CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP009483	Mycobacterium kansasii 824, complete genome	23 crisprs	WYL,cas4,DEDDh,csa3,DinG,cas3,PD-DExK	18	29	2	0

1. NZ_CP009483

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009483_1

• CRISPR_ID: NZ_CP009483_1
• CRISPR_location: 465950-466063
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP009483_1

Consensus_repeat	Method
GGCTGACCGTATTGGCCGGGCTGG	CRISPRCasFinder

spacers of NZ_CP009483_1

>1.1|465974|21|NZ_CP009483|CRISPRCasFinder
CCGGGCGCCCCGTACTGGCCG
>1.2|466019|21|NZ_CP009483|CRISPRCasFinder
CCGTATTGGCCGGGCTGGGCC

CRISPR arrays and Neighbor proteins around NZ_CP009483_1

CRISPR arrays

The CRISPR arrays of NZ_CP009483_1

>merge|NZ_CP009483|1|465950-466063|CRISPRCasFinder
GGCTGACCGTATTGGCCGGGCTGGCCGGGCGCCCCGTACTGGCCGGGCTGGCCGTACTGTGCCGGCTGGCCGTATTGGCCGGGCTGGGCCGCCTGACCGTACTGCCCGGGCTGG

>NZ_CP009483|1|1|465950-466063|CRISPRCasFinder
GGCTGACCGTATTGGCCGGGCTGG	CCGGGCGCCCCGTACTGGCCG
GGCTGGCCGTACTGTGCCGGCTGG	CCGTATTGGCCGGGCTGGGCC
GCCTGACCGTACTGCCCGGGCTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_036395967.1|480872_482075_-|hypothetical-protein	unknown	unknown	gnl|CDD|380462
NZ_CP009483.1|WP_023364655.1|454518_454731_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036395964.1|466399_469126_-|RNA-helicase	unknown	unknown	gnl|CDD|226947
NZ_CP009483.1|WP_023364672.1|471442_472441_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP009483.1|WP_023364666.1|464587_465544_+|5'-3'-exonuclease	unknown	unknown	gnl|CDD|214682
NZ_CP009483.1|WP_052492268.1|475185_479139_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NZ_CP009483.1|WP_023364670.1|470143_470410_-|twin-arginine-translocase-TatA/TatE-family-subunit	unknown	unknown	gnl|CDD|234797
NZ_CP009483.1|WP_080673983.1|459799_460585_+|hypothetical-protein	unknown	unknown	gnl|CDD|283837
NZ_CP009483.1|WP_023364665.1|463419_464541_-|aminopeptidase-P-family-protein	unknown	unknown	gnl|CDD|223085
NZ_CP009483.1|WP_023364675.1|479481_480855_+|MFS-transporter	unknown	unknown	gnl|CDD|340887
NZ_CP009483.1|WP_023364677.1|482077_483859_-|SyrP	unknown	unknown	gnl|CDD|165707
NZ_CP009483.1|WP_080674188.1|453356_453743_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023364671.1|470477_471446_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP009483.1|WP_036396015.1|456202_456496_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023364660.1|459015_459474_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_080673985.1|469147_470101_-|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl|CDD|223876
NZ_CP009483.1|WP_080673984.1|460631_461123_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023364664.1|461150_463391_-|peptidase	unknown	unknown	gnl|CDD|273828
NZ_CP009483.1|WP_080673982.1|453805_454321_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023364673.1|472451_473795_-|Pup--protein-ligase	unknown	unknown	gnl|CDD|274725

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP009483.1|WP_023364671.1|470477_471446_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	1.6e-78	259.1	0.0
NZ_CP009483.1|WP_023364672.1|471442_472441_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	5.8e-69	227.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_036395967.1|480872_482075_-|hypothetical-protein	gnl|CDD|380462	cd19539, SgcC5_NRPS-like, SgcC5 is a non-ribosomal peptide synthetase (NRPS) condensation enzyme with ester- and amide- bond forming activity and similar C-domains of modular NRPSs. SgcC5 is a free-standing NRPS condensation enzyme (rather than a modular NRPS), which catalyzes the condensation between the SgcC2-tethered (S)-3-chloro-5-hydroxy-beta-tyrosine and (R)-1phenyl-1,2-ethanediol, forming an ester bond, during the synthesis of the chromoprotein enediyne antitumor antibiotic C-1027. It has some acceptor substrate promiscuity as it has been shown to also catalyze the formation of an amide bond between SgcC2-tethered (S)-3-chloro-5-hydroxy-beta-tyrosine and a mimic of the enediyne core acceptor substrate having an amine at its C-2 position. This subfamily also includes similar C-domains of modular NRPSs such as Penicillium chrysogenum N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase PCBAB. Condensation (C) domains of NRPSs normally catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). There are various subtypes of C-domains such as the LCL-type which catalyzes peptide bond formation between two L-amino acids, the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity.	1.60149e-16
NZ_CP009483.1|WP_080673985.1|469147_470101_-|twin-arginine-translocase-subunit-TatC	gnl|CDD|223876	COG0805, TatC, Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion].	1.44834e-77
NZ_CP009483.1|WP_036395964.1|466399_469126_-|RNA-helicase	gnl|CDD|226947	COG4581, COG4581, Superfamily II RNA helicase [DNA replication, recombination, and repair].	0
NZ_CP009483.1|WP_023364666.1|464587_465544_+|5'-3'-exonuclease	gnl|CDD|214682	smart00475, 53EXOc, 5'-3' exonuclease.	1.08496e-89
NZ_CP009483.1|WP_023364677.1|482077_483859_-|SyrP	gnl|CDD|165707	PLN00139, PLN00139, hypothetical protein; Provisional.	1.09816e-33
NZ_CP009483.1|WP_023364670.1|470143_470410_-|twin-arginine-translocase-TatA/TatE-family-subunit	gnl|CDD|234797	PRK00575, tatA, Sec-independent protein translocase subunit TatA.	4.7565e-39
NZ_CP009483.1|WP_080673983.1|459799_460585_+|hypothetical-protein	gnl|CDD|283837	pfam06259, Abhydrolase_8, Alpha/beta hydrolase. Members of this family are predicted to have an alpha/beta hydrolase fold. They contain a predicted Ser-His-Asp catalytic triad, in which the serine is likely to act as a nucleophile.	3.55063e-11
NZ_CP009483.1|WP_023364672.1|471442_472441_-|YafY-family-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	5.48143e-60
NZ_CP009483.1|WP_023364675.1|479481_480855_+|MFS-transporter	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.40989e-22
NZ_CP009483.1|WP_023364671.1|470477_471446_-|YafY-family-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.18156e-76
NZ_CP009483.1|WP_052492268.1|475185_479139_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP009483.1|WP_023364673.1|472451_473795_-|Pup--protein-ligase	gnl|CDD|274725	TIGR03686, pupylate_PafA, Pup--protein ligase. Members of this family are the Pup--protein ligase PafA (proteasome accessory factor A), a protein shown to regulate steady-state levels of certain proteasome targets in Mycobacterium tuberculosis. Iyer, et al (2008) first suggested that PafA is the ligase for Pup, a ubiquitin analog attached to an epsilon-amino group of a Lys side-chain to direct the target to the proteasome. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP009483.1|WP_023364664.1|461150_463391_-|peptidase	gnl|CDD|273828	TIGR01840, poly3-hydroxybutyrate_depolymerase_A_precursor, esterase, PHB depolymerase family. This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation].	3.14868e-07
NZ_CP009483.1|WP_023364665.1|463419_464541_-|aminopeptidase-P-family-protein	gnl|CDD|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	1.69806e-103

Protein sequences

>NZ_CP009483.1|WP_023364666.1|464587_465544_+|5'-3'-exonuclease
MSAPLLLLDGASMWFRSFFGVPSSITAPDGRPVNAVRGFIDSMAVVITQHRPGRLVVCLDLDWRPQFRVDLISSYKAHRVAETEPEGRPDIEEVPDELTPQVDMIMELLDAYGIPTAGAPGFEADDVIGTLAAQERHDPVVVVSGDRDLLQVVADDPVPVRVLYLGRGLSKATLFGPAEVAERYGLPADRAGSAYAELALLRGDPSDGLPGVPGVGEKTAAALLAAHGSLDQIMSAAHDPKSGMAKGLRAKVLGASDYIEVAGSVVRVATDSPVQLSTPTDALPLVAADPARTAELATRYGVGSSITRLQKALDALPA
>NZ_CP009483.1|WP_023364665.1|463419_464541_-|aminopeptidase-P-family-protein
MNSRRFDSAVYERRLAAAAANTADAGLAGLVITPGYDLRYLIGSRAETFERLAALVLPASGEPTLVVPRLELATFMESADALGLGVRTWVDGDDPYRLVSAALGGGPVATGVSDSMPALHLLPLAAALDVLPVLATDVLRELRMIKEEAEIDALRRAGSAIDRVHARVPELLVPGRTEADVAADIAEAIVAEGHSEVAFVIVGSGPHGADPHHRFSDRTLQAGDIVVVDIGGTVEPGYHSDCTRTYSIGEPEPVVAQHYSVLQRAQRAAFDAVRPGVPAAQVDAAARCLLAEAGLADYFVHRTGHGIGLCVHEEPYIVAGNDVALAAGMTFSIEPGIYFPGRWGARIEDIVVVTKDGALSVNQRPHELTVVPV
>NZ_CP009483.1|WP_023364664.1|461150_463391_-|peptidase
MSLLDLTLLPLRIARHVADVVVRPASPAPPAELVVVDGMPEGVPPAARKPEPKLPVPSGWPFGEEFPRTCGAARVAGGALFWTDFLYDDHGATGLPVGDLKVQAPPRGTYVYPAGPAAGNGADIFRVAIGLTETHTWWRVDWNTLVDATVPIALFTFDTDRGRAASADWPAGAGVRSAGIDMALLVSGRSARLIDLTTQVATPVEHSVDLPARSFLAQVPRSVLEPTGTWTVRLAAGLANAAGDGFADVPAEHGALPGQPNVYNVAFRTHDQEKPHLNFWSDAAQAAALTSGDVSEFAVAVQWDRLAARETAAEPVITGPSTRWYVSSVELGQGVADGTVLDTDPQFLGRVQPYSVCLPSTYAPGQALPLTLLLHSLALGQTQFAAIDPRLLHEVCETRGSVVVTPLGRGPSTWYFDAGELDVWEVWARVAEQLGTDPNRTVISGYSMGGYAAYKLGLSYPEVFAQAVVLAGPPTCGVRLLPNVDIPADLNLDSHCAREGDTWELLGNARWLPFVIAHGLIDELVPFASAAEQVLELDRLGYRYRFTVYPLEDHIAWVLQDKFDDPIAHMGTGLRQADPGHITFAWYPQLVRADLGIGPHQVWWLSELTADPAVTARRGATAEVDARSYARPDPMHSIRRHRGFVPHFDPTPGLYTELDWRVDGPAPVLPYLTLRLTGVASLTVDVERAGLASLPSSSIAVASDTAAQITLAGLPDGLQVRLDGQPVESIVAVPIGRHQISLVRTG
>NZ_CP009483.1|WP_080673984.1|460631_461123_+|hypothetical-protein
MVLLLGGCSPMYPFAHDADHPEHPLSDEQAMAQVIEPAKQITKVAGLRDVSGGFSWESCNDQGDPPYRGRVDMTFNVPPGIDHSAYFEQVAATMVAHGWSSGAPSGQHLFGTAIHNDGVMATIGVSPFLGADGASELSGECRDMNNHRTDSNGFSIKDQLRGQ
>NZ_CP009483.1|WP_080673983.1|459799_460585_+|hypothetical-protein
MGYDAPAFEFQSLEAAVTDPTKLQQVGTPWMARQGGAVLAADVNGLAVTHEGGTPSHVTVIGHSYGSTTVADAFANSGMRANDAVLIGCPGTDLAPSAADFHLNGGRVYVGAASTDAISWIAESGSAVPNWVNDALGAPLGPLAGLGTDPAHEGFGSVRFRAEVAGTHNVTPWFNDHSHYYNKGSEALHNITEITVGHGDHLAREGMLAPHRAEERISSPTQIRTPFGTIPLPHVEVTTPATVDPEWDRPGDSVTSDHDFK
>NZ_CP009483.1|WP_023364660.1|459015_459474_+|hypothetical-protein
MYPFAHDADRPEHPLSDEQAMAQVIEPAKQIAKVAGLQDVSGEFGWESCNDQGDPPYRSRVNVKFNVPAGMDRNAYFEQVAATMVAHGWLAGPPPGLRPFGTAIHKDGVMAIIGVSPFLGADGDVELSGECRNMGDHRHARWLNISDQLRGG
>NZ_CP009483.1|WP_036396015.1|456202_456496_-|hypothetical-protein
METGELRVDVYQLRASASQWRELSTRFSVLASPTPGRPCQPTTAAVGGAHTAVGLAAEVLTIRTQATTGAVKAGAEGYGSNEVTAAGEMAAVRPRMV
>NZ_CP009483.1|WP_023364655.1|454518_454731_-|hypothetical-protein
MPAIEKLTEYVLKFDWLSMSGLTARIYIGHVDGLDGAPPDMTELSDAEIIAGFPQWESVMEVREQYTYSP
>NZ_CP009483.1|WP_080673982.1|453805_454321_-|hypothetical-protein
MSPSTDPAEGQRQFASDVLQKLLRHIVIKNAENAGREAPGYYVFLVSHAWTEGPLMYLVYQASPSEITWGLVRDTRKSLIDPGPWTDSDDPALYYYLLDLEEGWSGPVCVEPQDDLDTIHWRGDQTEGLPERVSDIPNEYRHTPPPIPAPETPRNEASPAANEPRRYANPL
>NZ_CP009483.1|WP_080674188.1|453356_453743_+|hypothetical-protein
MIAVRYLLDRQPGEQLSYGPLGDGVRAAREPVYQRLVALWRARRAKTNTGREMRDLDALFIDLDSVVAQVSTIIAIEQAYARAERRAMAAAVVAEIRGDGPGVGSQLKAVQRAAADALGALEALSTTV
>NZ_CP009483.1|WP_036395964.1|466399_469126_-|RNA-helicase
MTDLPELTRFIAELPFSLDDFQRRACAALECGHGVLVCAPTGAGKTVVGEFAVHLALAAGGKCFYTTPLKALSNQKHTDLTARYGRDQIGLLTGDLSVNANAPVVVMTTEVLRNMLYADSPALQGLSHVVMDEVHFLADRMRGPVWEEVILQLPEEVRVVSLSATVSNAEEFGGWMQTVRGDTTVVVDEHRPVPLWQHILVGKRLFDLFAYDADAEQPRVNPDLVRHIAHRREADRMSDWQPRRQGGRGGQGRSRFYRPLPRPEVIAKLDSEGLLPAITFVFSRAGCDAAVQQCLRSPLRLTGEDERARIAEVIDHRCGDLADADLAVLGYYEWREGLQRGLAAHHAGMLPAFRHTVEELFAAGLIKAVFATETLALGINMPARTVVLERLVKFNGEQHLPLTPGEYTQLTGRAGRRGIDVEGHAVVIWHPSDNTSEPAEVAGLASTRTFPLRSSFVPSYNMTINLVHRMGPEQAHRLLEQSFAQYQADRSVVGLVRGIERGKRMLDEIAAELGGPNAPILNYARLRAQVSELERSQARASRLQRRQEANDALAALRKGDIITITHGRRGGLAVVLESARDSADPRPLVLTENRWAGRISSADYSGGAPPVGSMALPKRIEYRQPRVRRDLASALRSAAAGLPAPADRRGKKRTRQDPDLESLREQLRRHPCHHAGDVEVQVRQAERYLRIERDNTQLQRKVAAATNSLARTFDRIVGLLTERQFIHGPPTDPEVTDDGRLLARIYSESDLLVAECLRTGAWAGLKPPELAAVVSAVLYESRGSDEPSGVEAPTPGLRQALRQTARLSAQLRADEQTHRISQSREPDDGFVNVIYRWARTGDLGAALAAADVSGTGSPLSAGDFVRWCRQVLDLLDQVRNAAPDPEVRAVAKRAINDIRRGVVAVDAG
>NZ_CP009483.1|WP_080673985.1|469147_470101_-|twin-arginine-translocase-subunit-TatC
MGNGFRASARAATVLKRLNPRNRRSRVNPDATMSLVDHLTELRTRLLISLAAILITTIFGFIWYSHSVFGLQSLGEWLRHPYCSLPQSARADISADGQCRLLATAPFDQFMLRLKVGMTAGVVLACPVWFYELWAFITPGLYKKERRFAVAFVIPAAVLFVAGAVLAYLVLSKALGFLLTVGSDVQVTALSGDRYFGFLINLLVVFGVSFEFPLLIVMLNMTGMLTYERLKSWRRGLIFTMFVFAAVFTPGSDPFSMTALGVALTVLLELAIQIARLHDKRKAKREALIPDDEASAIDSPEPVPAPSVIGGSHDDVT
>NZ_CP009483.1|WP_023364670.1|470143_470410_-|twin-arginine-translocase-TatA/TatE-family-subunit
MGSLSPWHWAILAVVVIVLFGAKKLPDAARSLGKSMRIFKSEMREMQSETKNQPPALDTNPASPTPVQSQRVEPPASTEPGHTEARPA
>NZ_CP009483.1|WP_023364671.1|470477_471446_-|YafY-family-transcriptional-regulator
MTAVSTRLVRLLNMVPYFQANPRITRAEAATDLGVSAKQLEEDLNQLWMCGLPGYYPGDLIDFEFSGDTIEVTFSAGIDRPLKLTSPEATGLLVALRALADIPGVVDPRAARSAIAKISAAAGAAGPASTVSAADQPAPAEHAAAATVRAAVRDKRALTIDYYSASHDTLTTRTVDPIRVLLIGGHSYLEAWSREAEGVRLFRFDRIVEASELDEPAAPPEPALQAPPDTALFDADPSLPSATLRVAPSASWMLEYYPIRELRELPDGSCEVAMTYASEEWMTRLMLGFGSDVQVLAPDSLARRVRAAAEAALQAYRAAAQE
>NZ_CP009483.1|WP_023364672.1|471442_472441_-|YafY-family-transcriptional-regulator
MATSKVERLVNLVIALLSTRGYITAEKIRSSVAGYSDSPTAEAFSRMFERDKNELRDLGIPLEVGKVSNLDPTEGYRINRDAYALPPVDLTPDEATAVAVATQLWESPELVTATQGALLKLRAAGVDVDPVDSEAAVTIASPAGLTGLRGSENVLGILLSAIDSRQAVQFRHRSSRAEPYTTRTVEPWGVVTEKGRWYLVGHDRDRGATRVFRLSRISGEITPIGPAGAIAVPDDVDLRGIVAAKVTEAPTGMRATVWVAGGRATALRRAGQPVGPRRLAGRDGDVIELDIGSSDRLAREIAGYGADAIVLEPAILREDVLARLHAHAGAAR
>NZ_CP009483.1|WP_023364673.1|472451_473795_-|Pup--protein-ligase
MGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDSLVQLVTHDRAGEWVLEDLLIDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATFCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMCETTTMLKVGTAALVLEMIEAGVAFRDFSLDNPIRAIREVSHDVTGRRPVRLAGGRQASALDIQREYHARAVDHLQNREPNPQIEQVVDLWGRQLDAVESQDFAKVDTEIDWVIKRKLFQRYQDRYNMELSDPKIAQLDLAYHDIKRGRGVFDLLQRKGLAARVTTDEEIADAVDHPPQTTRARLRGEFISAAQAAGRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVKRLIASM
>NZ_CP009483.1|WP_052492268.1|475185_479139_-|non-ribosomal-peptide-synthetase
MAADGVQPLAAAAPPKLVPLSYAQRRLWFIDQLEGPSPIYNMALALRLCGPLDVEALRVAVTDVVGRHRSLRTVFPATDGIPEQRVIDATAADAGWQVTDAVAWPASRLPQAIAALVRYRFDLANQIPLRTELFSVGADEHVLVIVMHHIAADRWSLSPLLRDLATAYTARCAGAVPGWDELTLHYVDYCRWQRDQLGELDDTTSPICAGLAYWQQTLAGLPERLELPADRHYPQVARHEGAGVAVDWPVALRQSVARLAREHRATSFMVITAGVVALLARLSGNTDIAVGIPVAGRTEAAFEEMVGLFVNTVVLRISVAGNPNLTELITRVREASLDAYDHQDVPFEVVVERLNPTRSLTHHPLIQVMLAWQSPAPADELMLPGLCVSSIPADTYAAPLDLTLTFGDRFTPNGAHAGIGGEIIYRTDVFAAPSIERLRDRLERLLTAMTADPSAPLSSIDVLDAAEHAHLDAIGNRAALGKTFAPVSIPELFGAQVARTPRSVALTGVDRRLTYAQLERAANRLAHALIDAGVGPGAVVALLLARSVPATVAIIAVLKTGAAYLPIDTQHPSARIGFMLTDASPKAAITTTDLAPLLVAAGATDLAVIDVDDPRIDTYPSTAPPTPAADHVAYIMYTSGTTGTPKGVAITHRNVTQLFDVVPPFTATAGKAGAQCHSYSFDFSVWEMWGALLHGGRLVVVPDAVARSASDLHALLVREHVDVLTQTPSAIGMLPRRGLESAAVVLLGEVCPVELVDRWAPGRMMINTYGPTEATVWVSTSTPLVADSAPPPIGSPVPGAALFVLDGWLRPVPVGVVGERAGVGCGYWRRPALTAARFVACPYGVGQRMYRTGDLVRWRADGQLDYLGRADEQVKIRGYRIELGEVSTVLSEVAGGQQAVVIAREDRPGDRRLVGYVAGQLQVEQLRAQLSERLPDYMLPAAVVSVATLPLTVNGKLDKRALPAPDYADTTRYRAPTTAVEETLAGIYAEVLGLPRVGIDESFFDLGGNSLLAMRVVAGVRRSLKVDLPVRSLFDAPSVASLSQLLRRPTRSPEVTPVEVLRHAAGVPLFCIHTAVGLSWPYHALGAYLDCPIVGIQQVVDDDARPDSIRDMAQHYADTVQSLYPGGPYHLLGWSFGGIVVHELAVELRRRGCVVGRLIVLDATPRAEEADDAATAAAREGEILKYVLRANGIELPADDPGPFTYQQAEELIQQRQDANFGLPSAQLLQILITNSIANERYRSEHAPAVFDGDLILFAATRSGNGSTLLEDWRPYVRGHIVEYPVDATHNEMLNAESLRLFGAQLNAALVDGQVSGR
>NZ_CP009483.1|WP_023364675.1|479481_480855_+|MFS-transporter
MVGINRKGFSRGPAIRGGIHRLGAMLLPGSAAGRMLAISAGIDSLGTGLFFASFTLYFVGIVKIGAPQVALASTAAGILALFVPVPLGRLADRLGPGRLYIGLLVLRGLGYCCYAGVSGFKGFLVLTMVLTAADRASTPLQQSVVRALIGNQDGTRTMASIRGVRNVGLTAGFLVAAAAFATAAMSVFTVLFVANGVSFLVAAAMVWPTVSRTEAVAAPAPATAPTAGPTAGAAACPRSPFRDRWFVVFTIGNGVLWLHDSVLIVLLPIWVIKHTAVPAGWVPVFMAVNTVLTAVLQVYVARFANGAVAANRVLGLAGLLLISCCGFLAIGQAAPTAIAVVAVLTAVILLSVAENLHNVAAYELSAELSPEVASSRYLGAFSLAYTGQQVIGPAVMAVLMPVGLIGWPLLAGAFGAAVVVSRGAAGRCLAERAGAASRRPVGAHRFFRGLLSAACPA
>NZ_CP009483.1|WP_036395967.1|480872_482075_-|hypothetical-protein
MPGWLIGLREARSPLGADFAPLVFEASAIDLDMLVARLAVLASRHEALRLLWPDLSAAAPETVVDAVAGADTHAGDIGSFAAELALAGYRRAGKPLWRARLVATVQPQQQYVVMGLDRLISDPWSLHVLAQELCMLCQAGPPPDLGPAPAQFGAALAERAGGSDESDARTERLHWRRQLAGANFGADPRVPRAAATTARIRRVPLTVADEHAMVSLASAYRTTLLAPVVAAVHMVWRRQVDAAETVLLTEVGYRGTQALDGTVAPLMEPRPMRIVSDVGAGALISQARGALLDVLDNSCVPLAADPAPMQPFFDHPDRMTVLAEFDTANRPTVHESALNLLDEPSIWAVGPPRADIHVMVRGDHRAPSVYVADNPLAVTGRFADEFAHQLVWALREMSEV
>NZ_CP009483.1|WP_023364677.1|482077_483859_-|SyrP
MAGYQRQAAGFGLLCYGPADITDPHRSLLAFPHGGGSPHSFAKLSQELGPGYRVTAVDPPGRPRSRGPVLRELGELVEFYLEHLPAHLLGGVLVGHSVGAYVASALAARLEQQGRPARAVVMSAVVPPAYLDPARPLSKMTDAQRLDWCRTLGTFPVGDKDSAALFALFAEAIRADCEVYESAVCVSLDHTTPLLVLVGEADPACPVQQVAHWPDTHPQAVIRTLPGGGHMLPQDAAHSYAAEVAGFLRHGRNGSIATRPVAGHRRPWRREDMWLRARQGRRCLPVIFPRGRDTPAALHHVLVENDCLETFLTDHGALLARGWNVADARGLQLIVGSTGIEPTPYVGGNSPRTALGNGIYTSTEYPPEAPISPHNEMSYADHWPTRLYFCCQAPAAQGGETLLADGRALVTHPRLEEVVDCMQRKGIRYLRTMHSGSGPGKSWQQTFETADQETVAGLLRDSGAAATWLPGGALRIVECRPAFIHDSNSGRQVWFNQAEQWHHSALPVEIRNALLDEFGEDGLPHNAAYGDGEPIPERHLDAIRHVLEAVSVAHSWRHGDVLVVDNVTTLHGRAPYRGQRRVLVAMTDQVARG

Crispr_ID: NZ_CP009483_2

• CRISPR_ID: NZ_CP009483_2
• CRISPR_location: 536199-536307
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_2

Consensus_repeat	Method
AGCCCGGCGACTCAAACGTTACGAGCGGCCCGCGCAGCGGG	CRISPRCasFinder

spacers of NZ_CP009483_2

>2.1|536240|27|NZ_CP009483|CRISPRCasFinder
CCGTTGAGGAGCCGGGCAATCAGACCC

CRISPR arrays and Neighbor proteins around NZ_CP009483_2

CRISPR arrays

The CRISPR arrays of NZ_CP009483_2

>merge|NZ_CP009483|2|536199-536307|CRISPRCasFinder
AGCCCGGCGACTCAAACGTTACGAGCGGCCCGCGCAGCGGGCCGTTGAGGAGCCGGGCAATCAGACCCAGCCCGGCGACTCAAACGTTACGAGCGGCCCGCGCAGCGGG

>NZ_CP009483|2|2|536199-536307|CRISPRCasFinder
AGCCCGGCGACTCAAACGTTACGAGCGGCCCGCGCAGCGGG	CCGTTGAGGAGCCGGGCAATCAGACCC
AGCCCGGCGACTCAAACGTTACGAGCGGCCCGCGCAGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_042313224.1|531964_532819_+|PAC2-family-protein	unknown	unknown	gnl|CDD|378251
NZ_CP009483.1|WP_042313214.1|521616_522447_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP009483.1|WP_042311690.1|542493_542700_+|dihydroorotate-dehydrogenase	unknown	unknown	unknown
NZ_CP009483.1|WP_023364710.1|534940_536185_-|cysteine--1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside-ligase	unknown	unknown	gnl|CDD|183518
NZ_CP009483.1|WP_023364709.1|534022_534916_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235633
NZ_CP009483.1|WP_023364704.1|524248_526603_+|arylsulfatase	unknown	unknown	gnl|CDD|293749
NZ_CP009483.1|WP_036393495.1|541390_542440_+|lipoprotein	unknown	unknown	gnl|CDD|271320
NZ_CP009483.1|WP_036393185.1|522741_524229_+|arylsulfatase	unknown	unknown	gnl|CDD|293761
NZ_CP009483.1|WP_023364706.1|528266_531845_-|methionine-synthase	unknown	unknown	gnl|CDD|273959
NZ_CP009483.1|WP_023364715.1|540073_540904_-|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl|CDD|237134
NZ_CP009483.1|WP_080674189.1|532815_533994_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|169028
NZ_CP009483.1|WP_023364711.1|536606_537395_-|3'(2'),5'-bisphosphate-nucleotidase-CysQ	unknown	unknown	gnl|CDD|224139
NZ_CP009483.1|WP_042313221.1|526701_527949_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023364712.1|537899_538715_-|phosphatidylinositol-kinase	unknown	unknown	gnl|CDD|274813
NZ_CP009483.1|WP_023364714.1|539348_540077_-|phosphoglycerate-mutase	unknown	unknown	gnl|CDD|163560
NZ_CP009483.1|WP_080673987.1|549520_549979_+|PPE-domain-containing-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023364716.1|540965_541268_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023364701.1|521151_521433_-|phosphoribosyl-ATP-diphosphatase	unknown	unknown	gnl|CDD|212154
NZ_CP009483.1|WP_042313227.1|542726_543809_+|quinone-dependent-dihydroorotate-dehydrogenase	unknown	unknown	gnl|CDD|235388
NZ_CP009483.1|WP_023364713.1|538698_539286_-|DUF3090-domain-containing-protein	unknown	unknown	gnl|CDD|213872

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_042313224.1|531964_532819_+|PAC2-family-protein	gnl|CDD|378251	pfam09754, PAC2, PAC2 family. This PAC2 (Proteasome assembly chaperone) family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 247 and 307 amino acids in length. These proteins function as a chaperone for the 26S proteasome. The 26S proteasome mediates ubiquitin-dependent proteolysis in eukaryotic cells. A number of studies including very recent ones have revealed that assembly of its 20S catalytic core particle is an ordered process that involves several conserved proteasome assembly chaperones (PACs). Two heterodimeric chaperones, PAC1-PAC2 and PAC3-PAC4, promote the assembly of rings composed of seven alpha subunits.	5.13956e-54
NZ_CP009483.1|WP_042313214.1|521616_522447_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.55399e-12
NZ_CP009483.1|WP_023364710.1|534940_536185_-|cysteine--1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside-ligase	gnl|CDD|183518	PRK12418, PRK12418, cysteinyl-tRNA synthetase; Provisional.	0
NZ_CP009483.1|WP_023364709.1|534022_534916_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|235633	PRK05872, PRK05872, short chain dehydrogenase; Provisional.	5.87161e-158
NZ_CP009483.1|WP_023364704.1|524248_526603_+|arylsulfatase	gnl|CDD|293749	cd16025, PAS_like, Bacterial Arylsulfatase of Pseudomonas aeruginosa and related proteins. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	0
NZ_CP009483.1|WP_036393495.1|541390_542440_+|lipoprotein	gnl|CDD|271320	cd05819, NHL, NHL repeat unit of beta-propeller proteins. The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.	3.04721e-05
NZ_CP009483.1|WP_036393185.1|522741_524229_+|arylsulfatase	gnl|CDD|293761	cd16142, ARS_like, uncharacterized arylsulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	6.08173e-175
NZ_CP009483.1|WP_023364706.1|528266_531845_-|methionine-synthase	gnl|CDD|273959	TIGR02082, Methionine_synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase. This family represents 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), one of at least three different enzymes able to convert homocysteine to methionine by transferring a methyl group on to the sulfur atom. It is also called the vitamin B12(or cobalamine)-dependent methionine synthase. Other methionine synthases include 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (MetE, EC 2.1.1.14, the cobalamin-independent methionine synthase) and betaine-homocysteine methyltransferase. [Amino acid biosynthesis, Aspartate family].	0
NZ_CP009483.1|WP_023364715.1|540073_540904_-|undecaprenyl-diphosphate-phosphatase	gnl|CDD|237134	PRK12554, PRK12554, undecaprenyl pyrophosphate phosphatase; Reviewed.	2.70981e-109
NZ_CP009483.1|WP_080674189.1|532815_533994_-|FAD-dependent-oxidoreductase	gnl|CDD|169028	PRK07588, PRK07588, FAD-binding domain.	1.27258e-73
NZ_CP009483.1|WP_023364711.1|536606_537395_-|3'(2'),5'-bisphosphate-nucleotidase-CysQ	gnl|CDD|224139	COG1218, CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase [Inorganic ion transport and metabolism].	3.14032e-77
NZ_CP009483.1|WP_042313221.1|526701_527949_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.04013e-55
NZ_CP009483.1|WP_023364712.1|537899_538715_-|phosphatidylinositol-kinase	gnl|CDD|274813	TIGR03843, Phosphatidylinositol_3-_and_4-kinase, conserved hypothetical protein. This model represents a protein family largely restricted to the Actinobacteria (high-GC Gram-positives), although it is also found in the Chloroflexi. Distant similarity to the phosphatidylinositol 3- and 4-kinase is suggested by the matching of some members to pfam00454.	8.0075e-130
NZ_CP009483.1|WP_023364714.1|539348_540077_-|phosphoglycerate-mutase	gnl|CDD|163560	TIGR03848, MSMEG_4193, probable phosphomutase, MSMEG_4193 family. A three-gene system broadly conserved among the Actinobacteria includes MSMEG_4193 and homologs, a subgroup among the larger phosphoglycerate mutase family protein (pfam00300). Another member of the trio is a probable kinase, related to phosphatidylinositol kinases; that context supports the hypothesis that this protein acts as a phosphomutase.	4.17924e-121
NZ_CP009483.1|WP_080673987.1|549520_549979_+|PPE-domain-containing-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	0.000296234
NZ_CP009483.1|WP_023364701.1|521151_521433_-|phosphoribosyl-ATP-diphosphatase	gnl|CDD|212154	cd11547, NTP-PPase_HisE, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Mycobacterium tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs. This family includes M. tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs. M. tuberculosis HisE is encoded by the hisE gene, which is a separate gene presenting in many bacteria and archaea but is fused to hisI in other bacteria, fungi and plants. HisE is responsible for the second step in the histidine-biosynthetic pathway. It can irreversibly hydrolyze phosphoribosyl-ATP (PRATP) to phosphoribosyl-AMP (PRAMP) and pyrophosphate. HisE dimerizes into a four alpha-helix bundle, forming two inferred PRATP active sites on the outer faces. M. tuberculosis HisE has been found to be essential for growth in vitro, thus making it a potential drug target for tuberculosis.	2.30197e-44
NZ_CP009483.1|WP_042313227.1|542726_543809_+|quinone-dependent-dihydroorotate-dehydrogenase	gnl|CDD|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	0
NZ_CP009483.1|WP_023364713.1|538698_539286_-|DUF3090-domain-containing-protein	gnl|CDD|213872	TIGR03847, TIGR03847, conserved hypothetical protein. The conserved hypothetical protein described here occurs as part of the trio of uncharacterized proteins common in the Actinobacteria.	2.13336e-87

Protein sequences

>NZ_CP009483.1|WP_023364710.1|534940_536185_-|cysteine--1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside-ligase
MRSWSSAPVPNLPGRGPELRLYDTADRQVRPVTPGPKATMYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHDVQYVQNVTDVDDPLFERADRDGVDWRELADREVKLFRADMEALRVLPPHDYVAATEAVAEMVELIEKMLASGAAYTVDPEIGDYPDIYYRADATVQFGYESGCDRDTMLTLFEQRGGDPSRPGKTDQLDALLWRAARAGEPSWPSPFGPGRPGWHVECAAIALSRINSGLDIQGGGSDLIFPHHEFTAAHAECVTGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSTLRAQGVEPSAVRLGLLAGHYREDRFWTHQVLDEAAGRLQRWRTATALPAGPDAADVIARVRRYLADDLDTPKAIAALDGWATDALEYGGHDESAPTSVATAIDALLGVDL
>NZ_CP009483.1|WP_023364709.1|534022_534916_-|NAD(P)-dependent-oxidoreductase
MTSVQDKVVFITGGARGIGAEVARRLHNKGAKLVLTDIGTAELTTIAAELGGDGRVLTVVADVRDLSAMQAAADLAIEKFGGIDVVIANAGIASYGSVLQVDPEAFKRVLDVNVLGVFHTVRATLPAVIERRGYVLIVSSLAAFAASPGLAPYNATKAGVEIFANALRLEVAHHGVSVGSAHMSWIDTALVRDTKADLPAFDELLRRLPWPLNLTTSVNKCAAAFVKGIEGRKTRIFCPRWVGLFRWLKPVLSTSVGERPIRKITAELLPRMDAEAAALGRSTSAYTHALDNASEKQ
>NZ_CP009483.1|WP_080674189.1|532815_533994_-|FAD-dependent-oxidoreductase
MAICGAGTAGLSLAERLSALGAEVVVLERSSGPRTHGHMIDFYGAGYDAAEAIGVLPAIQRVGYPLGDSSLIDRHGRRRAALPYRQIARALDGRLCRVMRPDLEKVLLDNLPPQVELRFGATVSDVAQRDDRVTVTLQRGAQLDADLLVGADGIHSTVRTLVFGVEPQYLRYPGFRSASFVLDAPGVRGSAAEHVVFTDTADRQLGLHLLRDGRTAVTAVYRTVDASPPHDVRAALREEYAGMGGLVAEVLDRCPEDGAVEYDQVAQIQMPRWSSKRVVLIGDASFAVSALSRQGASLAVASAYVLSEQLRKTSSVERALAFYERLWRPVVEDKQQSGQAASGWLWPGPSQSAIRRAMLRLSWRPLVNRFIEATLAGEPTALITMLRLGSGD
>NZ_CP009483.1|WP_042313224.1|531964_532819_+|PAC2-family-protein
MLPELHNTVVVAAFEGWNDAGDAASDAVSHLADIWDARPIVEIDDEAYYDYQVNRPVIRQVDGVTRELEWPAMRISHCRPPGSDRDVVLMHGVEPNMRWRTFCAELLAIVDKLNVDTVVILGALLADTPHTRPVPVSGAAYSPESAQIFGLQETRYEGPTGIAGVFQYACVAAGIPAVTFWAAVPHYVSHPPNPKATVALLRRVEDVLDVEVPLGDLPTQAEAWAQEISEMAAEDDELAEYVQSLEQHGDAAVDVNDVLGTIDGDALAAEFERYLRRRRPGFGR
>NZ_CP009483.1|WP_023364706.1|528266_531845_-|methionine-synthase
MTAANKPRYDTDLLDVLAQRVVVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVLETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADKIRDLSEKGTTIARRVADELSTPERKRYVLGSMGPGTKLPTLGHTDYAVIRDAYTEAALGMLDGGADSILVETCQDLLQLKAAVLGSRRAMKQAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSEHLRYLSRHARIPVSVMPNAGLPVLGAKGAEYPLRPDELAEALSGFIAEFGLSLVGGCCGTTPAHIREVAAAVVGAPRPERQVSFEPSVSSLYSAVPFAQDASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDSTETPVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMELVAEHGAAVVALTIDEEGQARTAEKKVEIAERLINDITTNWGVDESSILIDTLTFTIATGQEESRKDGIETIEAIRELKKRHPDVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRTVALDLVYDRRRDGYDPLQELMRLFEGVSAASSKESRAAELAKLPLFERLAQRIVDGERNGLEADLDEAMTQKPPLEIINENLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKSADVVGMSGLLVKSTVVMKENLEEMNSRGVAEKFPVLLGGAALTRSYVENDLADIYEGEVHYARDAFEGLKLMDTIMSSKRGEAPDVDSPEAIQARKKEAERKARHERSKRIAAQRKAAEEPVEIPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGMLDERALFLGQWGLRGQRGADGPSYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGDEVVVLTEPAADAEERYRFRFPRQQRGRFLCIADFVRSREHARERGQVDVLPFQLVTMGQPIADFANELFAADSYRDYLEVHGIGVQLTEALAEYWHRRIREELRYSADRTMAAEDPDAVEDYFKLGYRGARFAFGYGACPDLEDRAKMMQLLEPDRIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
>NZ_CP009483.1|WP_042313221.1|526701_527949_-|PPE-family-protein
MSAPVWMAFPPEVHSALLSAGPGPASLIAAAQAWSSLSAEYGAVADELAPVVAALRTEAWRGTAAECCVAAYVPYLAWVMQESADCAQVAAVHEITAAAYQAALAAMPTLGELAANHATHAVLLATNFFGVNAIPIAFNEADYARMWMQAATIMNVYETTSSPAVASTPHTPPAPAIIKPGAGLVNAIETTITPFPIWQILQILLDAVVGVLHCIRESLVATVLALLFIPLCVLLAVIALLTGHVAMAEQFLGFIVNLAIIPFQFFLEAGWIFIVGLADICELVIAWFLGNLGFVGGPGLVTQLATTTALSGGAALGVGALKGTTVALELAPASFAAMAVGADGSLATAGSAVSPAELGGPVGFAGTITNGTVPQAGGLTTLSGHTCCDGVQVPMLPSGWAQHVCGDDSTSWVLG
>NZ_CP009483.1|WP_023364704.1|524248_526603_+|arylsulfatase
MAITEYRPGTTFPGVIGRTADESTPAWPALKRPAEGAPNVVFIVLDDTGYGHLGCFGSPISTPNIDALAADGLRYSNMHTTALCSPSRSCILNGRNHHSNHLACLTNGSTGFPGSDGYIPFENGFLSEILRAQGYNTYCVGKWHLAPEETMTAAGPYDRWPLGRGFERYYGFLGGDTHQYYPDLVRDNSQTEPEATPEQGYHLTPDLVNKAKAMIADAKQVAPDKPFFLYFAPGATHSPHHVPKQWADRYAGKFDAGWEAYRQRVFTRQRELGLLPATAELSAPDPDVADWETLPADERRLYARMMEVFAGFLEHTDHYIGELVQFLKDLHEYDNTVIMLVSDNGASAEGGPTGSVTEVRFFNNVADTVEEGLARIDEIGGPTVFNHFPWGWTHAGNTPFRRWKRETYRGGSSDPLIVTWPRGIAARGEVRSQYAHLIDMVPTVLEALRIDPPTSIGGVTQSPIEGVSFAHTFDDAAAPTRHLTQYFEMLGHRSIYHDGWRAVCPWPGTSFAESTHKFGDVITAEMLSQLDESGWELYHVAQDPAETTNLAGQERARLIAMITLWYSEAGRYNVLPIDSRGLARAFVERPQIAGANRTRYVLYPGTQAIPAAAAPKILNRPYSINAEVELTEESSGVLLSMGGNDGGITLYVKDGQLCYAHNYVAKEIFTIRSEQRVPPGRHFLSVEFTPTGPVDLKNGRGTPGDVTLFVDGAAVGRGEFPVTTPLRLAQGGAMLVGANTGSSVTPDYDPPFAFDGRIHRVIVDVSGEHVEDYQAQMKIALTKQ
>NZ_CP009483.1|WP_036393185.1|522741_524229_+|arylsulfatase
MAAETADAAARPNILVIWGDDVGMWNISAYHRGMMGGSTPNIDRIANEGMIFMDHYAQASCTAGRAAFITGQYPIRVGLSTVGLPGSDIGLQKEDPTLAEMVKPLGYTTGQFGKNHLGDRDEHLPTLHGFDEFFGILYHLNAGEYAEQYDFPTNPEIVEKFGFGQRGALHCWANPDGTQRIEDTGPYGRERQRTLDREFLTETKRFIRDAAAAETPFFVWHNSTRMHYRTNLAPEYDGKSGYGVYADGMMELDDHVGELLDLLDELGIADNTLVMWSTDNGAACNSWPDGGNHPFAREKGVGGYEGAFRVPALVRWPGVIPAGVASGEFMAMEDWIPTIMSMLGQPDLADSLKKGATIGGREYRVHLDGVDQTDLLTGRGKSKRMEFYYFTETSLHGLRYGDWKVLLKTQDRWFNGIQQKLTTPLITNLKLDPFERFHKARGFDEWQENHAWLYGPAALQVMRFLATLHEFPPRMRSFGIDVDELLNQLNPARHR
>NZ_CP009483.1|WP_042313214.1|521616_522447_+|alpha/beta-hydrolase
MQWTTSGLRLRRRASRAGDLNWLFLPGGPGIGSESLHELVDTVDVPGCSWMVDLPGDGSNVNAPGAPADPYDLWPQVLLEAAHAVAHPVFVGHSTGGEYLLSVPALDGCLAGLALVSTAPDASWIPVFEHMTRNNRLPGVEYATTRYLSDPTDDHLRRVAVESAPWNFAAHTVARGTEILARLPYNARAAQWSEANFDRGYRSAWWPSTLPTLIVSGSADRIVTQTLWHDKRFHTPNTTWRVIAGAGHFPWIEQPAAVHDAFAALVGQIDNRRTTD
>NZ_CP009483.1|WP_023364701.1|521151_521433_-|phosphoribosyl-ATP-diphosphatase
MKQSLAVKTFEDLFAELGDRARTRPAGSATVAALDAGVHWLGKKILEEAGEVWLAAEHEANDALAEEISQLLYWTQVLMISRGLSLDDVYRKL
>NZ_CP009483.1|WP_023364711.1|536606_537395_-|3'(2'),5'-bisphosphate-nucleotidase-CysQ
MSPAADDLTDAQLAADLAAEAGELLLALRDEVGFDHPWALGDAGDARANSLLVRRLRAARPGDAVLSEEAHDDLVRLKCDRVWIIDPLDGTREFSTRGRDDWAVHVALWQRTTNGRPQITDAAVSLPARGNIVYRSDTVTADAAPTGIPDVIRVAVSANRPPAILHYIQQTVDIELVRIGSAGAKAMAVIDGYADAYLHAGGQWEWDSAAPAGVVLAAGMHASRLDGSPLQYNQLDPYLPDFLMCRKELAPVLLGAMRRTWR
>NZ_CP009483.1|WP_023364712.1|537899_538715_-|phosphatidylinositol-kinase
MNPSNDECEVLRHGELTVLGRIRSASNATFLCESTLGGKTVHCVYKPVAGEQPLWDFPDGTLAGRELSAYLVSASLGWNIVPYTVIRDGPAGPGMLQLWVRQPGDSLDAEARPGPDLVDLFPTGKARPGYLPVLRAYDYAGDEVVLMHADDDQLRRMAVFDVLVNNADRKGGHILCGIDGRVYGVDHGVCMHVQDKLRTVLWGWAGKPIDEPTLEPIARLADDLRGSLADELRDHVTSAEIAALRRRVRALLDNPVMPGPNRHRPIPWPAF
>NZ_CP009483.1|WP_023364713.1|538698_539286_-|DUF3090-domain-containing-protein
MARAIHVFRTPDRFVAGTVGQPGNRTFYIQAAHDDRVVSVVLEKQQVAVLAERIGALLLEVNRRFGTPVPPEPAEVEDLNPLIMPVDAEFRVGTMGLGWDSEAQTVVVELLAVTDAEFDASVVLDDTDEGPDAVRVFLTPESARQFATRSNRVISAGRPPCPLCQEPLDPQGHICARTNGYRRDLLFGSDDEPEQ
>NZ_CP009483.1|WP_023364714.1|539348_540077_-|phosphoglycerate-mutase
MTVILLRHGRSTSNTAGILAGRSEGVGLDDKGREQATGLIDRFGDLPVRAVVASPLLRCRATVEPLADALCLEPLVDDRLAEVDYGDWTGRKIAELTNEPLWRVVQAHPSAAVFPGGEGLAQVQARAVTAVREHDRRLALEYGGDVLWLACTHGDVIKAVIADAYGMHLDSFQRITADPASASVIRYTELRPFVLHVNHTGARLSAGLRAAPPPKAEPGGEQPAAPDAEVPSGDAVVGGSTD
>NZ_CP009483.1|WP_023364715.1|540073_540904_-|undecaprenyl-diphosphate-phosphatase
MSWWQVISLAVVQGLTEFLPVSSSGHLAIMSRIFFSDDAGASFTAVTQLGTEAAVLVYFARDIVRILRAWVDGLVVKSHRNADYRLGWYVIIGTIPICILGLFFKDEIRSGVRNLWVVATAMVVFSGVIALAEYLGRQGRQVEQLNWRDAVVVGIAQTLALVPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSLPDAFHPVTEGMSATGPQLLVATLIAFVVGLSAVAWFLHFLLRHNMYWFVGYRIVVGVGVLVLLATGTVSAT
>NZ_CP009483.1|WP_023364716.1|540965_541268_-|hypothetical-protein
MTVTADRHVANKQFAIEDMSTGIFASGYGQVGDGRSFSFHIEHRSLVVEIYRPRLTAPVPQAEDVVARSVRSLVDIDVTDERSLAAAVRDSVAQAVPVSR
>NZ_CP009483.1|WP_036393495.1|541390_542440_+|lipoprotein
MLTATKQAVQRCLCAAAALLTLVTACSSNPLHTAPPTIQPAQPAVSPPVSQAPAGVIRPLSGHPQAALYDNGARRLVVLTPDADPSAPSGITVFDDAQTPSRVITLPGPATALTCDDHGTAYLAARGGYLVVDLSAGRIAQVSVADAAGTDFTAIARRADGKLVLGSADGAVYILDSESSGTARTANRIKIFARVDSLVTQGNTTVVLDRGQTSVTTIGADGRARQALRAGEGATTLAADPLGRVLVADTRGGQLLVYGVDPLILRQAYPVPQAPYGLAGSRELAWVSQTASNVVIGYDLSTGIPVEKVRYPTVQQPNSLAFDDASGTLYVVSGSGAGVQVIEHAAGIA
>NZ_CP009483.1|WP_042311690.1|542493_542700_+|dihydroorotate-dehydrogenase
MSDEYEWAPLRLPPEVTRLSASTRLSIEAEYRGWELTRVRLYTDGSRRVLLRRKKSRLDNASSDQPEP
>NZ_CP009483.1|WP_042313227.1|542726_543809_+|quinone-dependent-dihydroorotate-dehydrogenase
MYSLVRRLLFLLPPERAHTFVFALLRAVTAVAPARRMLSRWLGPTDPVLASTVFGVRFPGPLGLAAGFDKDGTGLDTWGALGFGYAEVGTVTARPQPGNPPPRMFRLPADRALLNRMGFNNHGAGALAIRLTRHRPRVPIGVNIGKSKATPAGEAVDDYRASARLVGPLAAYLVVNVSSPNTPGLRDLQAVESLRPILTAVLAETSTPVLVKIAPDLSDSDIDDIADLAVELGLAGIVATNTTVSRDGLATPGVDELGAGGISGPPVAARAVQVLRRLQHRVGDRLVLISVGGIETVDDAWERITAGATLLQGYTGFIYGGGLWAKHIHDGIARRLHDGGFAPLADAGGPAARKAGKPPG
>NZ_CP009483.1|WP_080673987.1|549520_549979_+|PPE-domain-containing-protein
MDFAGLPPEHNSARMFAGAGSAPMLATAAAWQGLAAELGSSAFAFASQTSALCHPASARHAAHSFTARGAAFTDCAAAARGTAQDTTCSAAAAASAHARGTARAASASITPEADLTTSATACAAVASVAARAAAASVAADPSGTANASTAGE

Crispr_ID: NZ_CP009483_3

• CRISPR_ID: NZ_CP009483_3
• CRISPR_location: 1061615-1061683
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP009483_3

Consensus_repeat	Method
CCGATATTGCCGCTGCCCACGTT	CRISPRCasFinder

spacers of NZ_CP009483_3

>3.1|1061638|22|NZ_CP009483|CRISPRCasFinder
ACCGAAGCTGGTGTTCGAGTTG

CRISPR arrays and Neighbor proteins around NZ_CP009483_3

CRISPR arrays

The CRISPR arrays of NZ_CP009483_3

>merge|NZ_CP009483|3|1061615-1061683|CRISPRCasFinder
CCGGTGTTGACGTTGCCCGAGTTACCGAAGCTGGTGTTCGAGTTGCCGGCATTGAAGCTGCCCGCGTTG

>NZ_CP009483|3|3|1061615-1061683|CRISPRCasFinder
CCGGTGTTGACGTTGCCCGAGTT	ACCGAAGCTGGTGTTCGAGTTG
CCGGCATTGAAGCTGCCCGCGTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_036393041.1|1051566_1051824_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase	unknown	unknown	gnl|CDD|235686
NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|377587
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase	unknown	unknown	gnl|CDD|173288
NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein	unknown	unknown	gnl|CDD|377378
NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO	unknown	unknown	gnl|CDD|234622
NZ_CP009483.1|WP_036393017.1|1071595_1071916_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase	unknown	unknown	gnl|CDD|235551
NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein	unknown	unknown	gnl|CDD|377587
NZ_CP009483.1|WP_023365627.1|1066958_1067408_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era	unknown	unknown	gnl|CDD|234624
NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein	unknown	unknown	gnl|CDD|378566
NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase	unknown	unknown	gnl|CDD|235240
NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|235098

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	4.4e-19	63.7	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein	gnl|CDD|377378	pfam04536, TPM_phosphatase, TPM domain. This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II.	1.67335e-20
NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase	gnl|CDD|235686	PRK06061, PRK06061, amidase; Provisional.	0
NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	3.26736e-11
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	1.22235e-18
NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase	gnl|CDD|173288	PRK14827, PRK14827, undecaprenyl pyrophosphate synthase; Provisional.	0
NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era	gnl|CDD|234624	PRK00089, era, GTPase Era; Reviewed.	3.57123e-165
NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase	gnl|CDD|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0
NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0
NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	5.70515e-10
NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO	gnl|CDD|234622	PRK00085, recO, DNA repair protein RecO; Reviewed.	6.40078e-88
NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	2.89137e-115
NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	8.06071e-47
NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein	gnl|CDD|378566	pfam11139, SfLAP, Sap, sulfolipid-1-addressing protein. SAP is a transmembrane transport protein with six predicted transmembrane helices, with a hydrophilic domain between helices 3 and 4. This hyrodphobic region is highly variable among identified Gap-like (GPL, peptidoglycolipid, addressing protein) proteins and may be involved in substrate recognition. SAP also belongs to the LysE protein superfamily (pfam01810), whose members have been implicated in small molecule transport in bacteria. Other Gap proteins export metabolites across the cell membrane so it is possible that Sap specifically may be involved in transport of sulfolipid-1 across the membrane.	5.72001e-23
NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0
NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0

Protein sequences

>NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein
MIGKPLSRPGFVIVVVVVASVAMWGTVLVLGLVATADPVRIGISVLLSSQPRAVGQLVAFWLGGIFTSVALATGVLFGLRGFALDVMHRVEVATASSTAGHIQIAMGVTALLIAALAIRLSPGQRIRLGMTGANPSQLQVRTSMTISRLSTRAQFALQARPLRVAFVLGVGMLADLRFLVALTAILASGAAVATQVTAAGVYTLVALTFVELPLASQLAAPAKTGQIMSVLQRWVKARRHQIFAVVIALLGAFLMTRGMGRV
>NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C
MSRREFFAKLTGAGAAALLMDFAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYFGTLSSTRGFNDPSPAYQQKGWNPMTQALDPAGITIPFRLDTTRGPILDGECVNDPDHAWIAMHNSWNNGGNDNWLPAQSATRTGPYVPMVMGYYTRQDIPIHHLLADTFTICDGYHCSLLGGTLPNRLYWMSATIDPAGTNGGPQLVEPGFLPEQQYSWRIMPENLEDAGISWKVYQSKDAGRFINTPISNNGLVQAFRQSANPRSNLARFGIAPTYPLDFAADVKGNRLPQVSWLVPPFIQSEHPALPVALGAVAMVNALRILLSNPAVWEKTALIISYDENGGFFDHVTPPTAPPGTPGEYVTVPDINAVTGSGGIRGPIGLGFRVPCLVISPFSRGGLMVHDTFDHTSQLKLIRARFGVPIPNLTAWRDGVVGDMTSAFNFATPPNPTRPNLSHPLLAAVPKLPQCIPNVVLGTTDGTLPAIPYRVPYPQIMPTQESSPTRGIPSGLC
>NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C
MTRRQFFAKAAAATTAGALTSLAAPIIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYFGTLSGTRGFNDPSPAFAQKGWNPATQAVDPAGTTIPFRFDTTRGPLLDGECVNDPDHGWIAMHNSWNGGANDGWLPAQAASSPLQGNVPVTMGYYTRRDLPIHYLLADTFTVCDAYYCSLLGGTTPNRLYWMSAWIDPDGTNGGPILIEPNIQPQQKLSWRIMPQNLEDAAVSWKVYQNKFLGPLNNTVVGYNGLINDFQQAADPRSNLARYGIAPTYPLDFAADVKNNALPKVSWVLPGFLLSEHPALPVSIGAVGIVDVLRILLSNPAVWEKTAVIVNYDENGGFFDHVTPPTPPPGTPGEYVTVPDINAVPGSGGIRGPIGLGFRTPCIVISPYSRGPLMVHDTFDHTSTLKLISARFGVPVPNLSAWRNGVVGDMTSTFNFAVPPNPSKPNLDHPLLKSVPKLPQCVPNAVLGTTTKTSIPYRVPFPQMMPTQETSPTRGIPSGVC
>NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C
MSRREFLAKATGAGAAAFLTDWAAPVIEKAYAAGPCSGHLTDIEHIVLCLQENRSFDHYFGTLSSVDGFDTPTPLFAQKGWNPQTQAVDPAGITLPYRIDTTRGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLAAQARTRSAANTPVVMGYYARPDIPIHYLLADTFTVCDHYHSSLLGGTMPNRLYWISGTVNPDGDQGGPQIVEPSIQPKLTFSWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKAAGDPRSDLARYGIAPTYPMDFVLDVINNRLPQVSWVVPLTVDSEHPSFPIAVGAVTIVNLIRTLLRNPAVWEKTALIIAYDEHGGFFDHVTPPTAPPGTPGEWIPNSVDINKVDGSGGIRGPIGLGYRVPCFVISPYSRGGLMVHDQFDHTSQLQLIGKRFGVPVPNLTPWRASLTGDMTSAFNFAAPPDPSRPNLDHPARQLPKVANCVPNVVLGFLNEGLPYRVPYPQTMPVQESGPVRGIPSGIC
>NZ_CP009483.1|WP_036393041.1|1051566_1051824_-|hypothetical-protein
MLGGLSVPLSWGTAVPPDDYDHWAKEDEAAEVAVVPGAVDPEPAESSTDEWDEWAEWNEWEAANAEPRFEVPRSSRVVPHSPAAG
>NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target
MATRFMTDPHAMRAMAGRFEVHAQTVEDEARRMWASSQNISGAGWSGLAEATSLDTMGQMNQAFRNIVNMLHGVRDGLIRDANNYEQQEQASQQILSS
>NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein
MTINYQFGDVDAHGATIRAQAASLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGSNMAQTDSAVGSSWA
>NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein
MRIARLLGVVLTVVTVGLAGGVLLAPPSAAQPPFRLPGYVTDNAGVLSGSDRAEVTSAINELYADRHIRLWVVYVDNFSGQSAMNWGQSTFRSSELGSYDALLAVATVARSYVFLVPSTVPDVSAGQVEELRRNQIEPALRSGDWGGAAVAAANGLNKSPSSSGRVTLLVALGVIVVAVVILLVVTRYRARRRRADALAAARRVDPTDQRALAAVPPDILDDLSRSMVVAVDNAVRTSSNELAVAIDEFGQERTAPFTRAVDNAKAALAQAFSVRQQLDDSVPETPAQRRELLTRVIVSAATADRELEAQTEAFEQLRDLVINAPSRLDMLTQQYVELTTRIAPSQQRLAELHDEFGETALTSVAGNVTAAQERLVFADRNIGMARELSTQAVSGGQSGLVDAVRAAESALGQARSLLDAVDSAAGDIRHAVTELPSVLADVTAGIKQADEQLQKTPGSTSAHTRELVAARDAAAQALEESRNTRGTGVADPLGTFARVSKAGADLDRVLTTVAQEQANAERLNRSFEQALFTAESRVRAVSDYIDTRRGSIGPEARTRLAEAKRQLHAARDKRSTNVTEAVGHANAASTLAANAQALANADVQAAQRAYTRQGGDNAGAILGGIIIGNLLSGGLRGGFGGWSPTSFGGSSSSSSGSSGGGFMGGGGRF
>NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase
MTTNQQDPYGDFDRQRRVAEPPKSAGLPGTEGQHRTDFARDRARVLHSAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDPDLVELAGLAHDIGHPPYGHNGERALDDVAACCGGFEGNAQNFRILTSLEPKVLDSQGLSAGLNLTRAALDAVTKYPWTRGDGRRKFGFYEEDQQPAAWVRTGAPADRPCLEAQVMDWADDVAYSVHDVEDGVVSERIDLRVLADHDDAAALARLGQSEFRRLGADELMAAARRLSALPVVAAVGKYDATLAASVALKRLTSELVGRFASAAIATTRAVAGSGPLTRYQAELQIPDLVRAEVAVLKILALQFIMSDPRHLEAQARQRERIHRVAQWLSSGAPRTLDPVFAAAYHTADDDAARMRVIVDQIASYTEGRLERIDAGQFPGRTTVLH
>NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase
MSSPAGRSRISDRDIAAIRDGARIEDVVGDYVQLRRAGADSLRGLCPFHNEKSPSFHVRPNHGHFHCFGCGEGGDVYAFIQKIEHVSFVEAVELLADRIGYTISYTGAATSVQRDRGSRSRLLAANAAAAEFYAVALESDEAAPARHYLTQRNFDAQAARRFGCGFAPSGWDSLTKHLQRKGFEFKELEAAGLSRQGRHGPMDRFHRRLLWPIRSSAGEVIGFGARRLFDDDPMEAKYVNTPETLLYKKSSVMFGIDLAKRDIAKGHQAVVVEGYTDVMAMHLAGVTTAVASCGTAFGDEHLAMLRRLMMDDSFFRGELIYVFDGDAAGRAAALKALDGEQNLAGQSFVAVAPDGMDPCDLRLASGDAALRDLVARRTPLFEFAIRSALAETDLNSAEGRVAALRRCVPMVGQIKDPMLRDEYARQLAGWVGWDDVAQVVDRVRSQAKTPAKVPGRGHPGSKAPRRATQQPPDAPSAEPAAARPDPRDPTLWPQREALKSALQYPALAGPVFDTLTVESFTHPGYCAVRAAIEAAGGTSAGVTGAQWMDMVARQTTSPLTTGLINELAVEAIAVDDDKLPRYIGGVLARLQEVWMGRQIAEVKSKLQRMSPIEHGDEYHALFGDLVAMEAYRRSLLEQASGNDLTA
>NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase
MASVIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVITSRDDVVGIDSSIILPREVWVASGHVEVFHDPLVESLITHKRYRADHLIEAYEAKHGHPPPNGLADIRDPDTGEPGQWTEPREFNMMLKTYLGPIETEEGLHYLRPETAQGIFINFANVVTTSRKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWYVELGIDPQNLRLWEHPKEKLSHYSDRTVDIEYKFGFLGNPWGELEGVANRTDFDLSTHSKHSGTDLNFYDQVNDTRYTPYVIEPAAGLTRSFMAFLIDAYSEDEAPNAKGVMEKRTVLRLDARLAPVKAAVLPLSRHADLSPKARDLAAELRTCWNIEFDDAGAIGRRYRRQDEIGTPYCVTVDFDSLEDNAVTVRERDAMTQERIAIDKVADYLAVRLKGCC
>NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator
MATSPATPVAVDDLVGHHEHGARSSSGHPASPAPPPREILDAAGELLRALAAPVRIAIVLQLRESQRCVHELVDALGVPQPLVSQHLKILKAAGVVTGERSGREVLYRLADHHLAHIVVDAVAHASEESP
>NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor
MTGPSVRSTRQRAAISTLLETVDDFRSAQELHDELRRRGENIGLTTVYRTLQSMAAAGVVDTLRTDTGESVYRRCSEHHHHHLVCRSCGSTIEVADHEVEAWAAEVAARHGFSDVSHTIEIFGNCADCRS
>NZ_CP009483.1|WP_023365627.1|1066958_1067408_-|hypothetical-protein
MPSLQQRLASILPDVLSVEQEPDGAMTVRHSGTFASLRVVSIAEGLELVSLTQILAWDLPLTRKIRERAAKQARDVNFGAVTVLEKSPDNGTAKGAAKTAAKTASKTGDVMLRYNFPGAGLSDDALRTLILLVLDTGVQVRDALIAGAR
>NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase
MAKKAERTLTSADFPQLPPAPDDYPTFPDTSTWPVVFPALPPSPDGGPRRPPQHISKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLRRTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSAEEVRFLMGFNRDVVRRRRENLKEMGVRIRWVGSRPRLWRSVINELAVAEQMTKYNDVITINYCVNYGGRTEIADATRQIAREVAAGRLNPERISESTISRYMQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGSA
>NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO
MRLYRDRAVVLRQHKLGEADRIVTLLTRDHGLVRAVAKGVRRTRSKFGARLEPFAHIDAQLHPGRNLDIVTQVVSVDAFATDIVNDYGRYTCGCAMLETAERLAGEERAPAPALHRLTVGALRAVADGRRPRDLLLDAYLLRAMGIAGWAPALTECARCATPGPHRAFHIAAGGSVCAHCRPAGATTPPLGVLELMSALHDGDWAAAEQAPQSHRGYVSGLVAAHLQWHLERQLKTLPLVERTYRIDHTIAERRAALTRQVGECG
>NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase
MVGASESASGAVSGSGNQRLPTLTDLLYQLANGSVTSVDLVRRSLREIQASQSTLNAFRVVFTESALADAAAADRRRAAGDTGPLLGIPIAVKDDVDVAGVPTAYGTEGYVAPATADSEVVRRLKAAGAVIVGKTNTCELGQWPFTSGPGFGHTRNPWARRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRVPAAWTHLVGIKPQRGRISTWPLPEAFNGITVNGVLARTVADAALVLDAASGNVEGDLHRPPPVTASDYVGIAPGPLKIALSTRAPFNGFRAKLHPEILAATRQVGEQLQLLGHTVVRGNPDYSVQMSWDFLARSTAGLWEWAQRLGDDVTLDPRTVSNLRTGHMLSQAILRSARRHEAAAHRRVGSIFDIVDVVLAPTTALPPPLARAFDQMGGLATDRAIIAACPYTWPWNLLGWPAINVPAGFTVEGLPIGVQLMGPANSEGMLISLAAELEAVSGWAAKQPTVWWNEGTDTPAPHSVRPPQRWQR
>NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era
MTAEFRSGFVCLVGRPNTGKSTLTNALVGAKVAITSMRPQTTRHTIRGIVHRENFQIILVDTPGLHRPRTLLGKRLNDLVRATYAEVDVIGLCIPADEAIGPGDRWILEQIRSVAPGTTLVVIVTKIDKVPKDRVAAQLVAVGELVENLPGSTEIVPVSAVTGAQVDVLVDVLAGALPPGPAYYPDGELTDEPEEVLMAEFIREAALEGVHDELPHSLAVVIDDVSPRDGRDDLIDVHAVVYVERDSQKGIVIGKGGARLRQVGTAARGQIEKLLGTKVYLDLRVKVAKNWQRDPKQLGRLGF
>NZ_CP009483.1|WP_036393017.1|1071595_1071916_-|hypothetical-protein
MAEPADPEDAKLVMLARAAMARAGADSGAAVRDHEGRTYVAVPVNLPALRLTGLQAAVAAAVSSGAIGLEAAALVAGSVDDPGIAALRELSPMAVVVVTDSTGTPL
>NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter
MTGLAQLLGAIVLIGLGGVFAALDAAFSTVSLARVQELVREARPGAVALLKVMVERPRYINLVVLLRIVCEITATAFLVVFFRHNLNLNGGLFVAAAVMVVTSFVVIGVGPRTLGRQHAYSIALATAVPLQVISWLLMPISRLLVLLGNALTPGRGFRNGPFASEVELREVVDLAQQRGVVAADERKMIESVFELGDTPAREVMVPRTEMIWIEGDKSPAQAMNLAVRSGHSRIPVIGENVDDILGVVYLKDLVRQTFFSPGGGRESTVADVMRPAVFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDEAEIAPVEDLGDKRFRVSARLPIEDVGELYGMDFDGDLDVDTVGGLLALELGRVPLPGAEVVSHGLRLQAEGGRDHRGRMRIGTVLVSPVELGETVATDCSGYRPDEGDSDG

Crispr_ID: NZ_CP009483_4

• CRISPR_ID: NZ_CP009483_4
• CRISPR_location: 1061765-1061878
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP009483_4

Consensus_repeat	Method
CCGATATTGCCGCTGCCCACGTT	CRISPRCasFinder

spacers of NZ_CP009483_4

>4.1|1061788|22|NZ_CP009483|CRISPRCasFinder
CCCGAAGCCCGTGTTCCCCACG
>4.2|1061833|22|NZ_CP009483|CRISPRCasFinder
GACGGTACCCGAGTTGAAGAAG

CRISPR arrays and Neighbor proteins around NZ_CP009483_4

CRISPR arrays

The CRISPR arrays of NZ_CP009483_4

>merge|NZ_CP009483|4|1061765-1061878|CRISPRCasFinder
CCGGTGTTGACACTGCCCGCGTTCCCGAAGCCCGTGTTCCCCACGCCAGAATTACCGAAGCCTACGTTGACGGTACCCGAGTTGAAGAAGCCCACGTTACCGCTGCCTGAGTTG

>NZ_CP009483|4|4|1061765-1061878|CRISPRCasFinder
CCGGTGTTGACACTGCCCGCGTT	CCCGAAGCCCGTGTTCCCCACG
CCAGAATTACCGAAGCCTACGTT	GACGGTACCCGAGTTGAAGAAG
CCCACGTTACCGCTGCCTGAGTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_036393041.1|1051566_1051824_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase	unknown	unknown	gnl|CDD|235686
NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|377587
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase	unknown	unknown	gnl|CDD|173288
NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein	unknown	unknown	gnl|CDD|377378
NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO	unknown	unknown	gnl|CDD|234622
NZ_CP009483.1|WP_036393017.1|1071595_1071916_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase	unknown	unknown	gnl|CDD|235551
NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein	unknown	unknown	gnl|CDD|377587
NZ_CP009483.1|WP_023365627.1|1066958_1067408_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era	unknown	unknown	gnl|CDD|234624
NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein	unknown	unknown	gnl|CDD|378566
NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase	unknown	unknown	gnl|CDD|235240
NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|235098

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	4.4e-19	63.7	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein	gnl|CDD|377378	pfam04536, TPM_phosphatase, TPM domain. This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II.	1.67335e-20
NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase	gnl|CDD|235686	PRK06061, PRK06061, amidase; Provisional.	0
NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	3.26736e-11
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	1.22235e-18
NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase	gnl|CDD|173288	PRK14827, PRK14827, undecaprenyl pyrophosphate synthase; Provisional.	0
NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era	gnl|CDD|234624	PRK00089, era, GTPase Era; Reviewed.	3.57123e-165
NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase	gnl|CDD|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0
NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0
NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	5.70515e-10
NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO	gnl|CDD|234622	PRK00085, recO, DNA repair protein RecO; Reviewed.	6.40078e-88
NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	2.89137e-115
NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	8.06071e-47
NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein	gnl|CDD|378566	pfam11139, SfLAP, Sap, sulfolipid-1-addressing protein. SAP is a transmembrane transport protein with six predicted transmembrane helices, with a hydrophilic domain between helices 3 and 4. This hyrodphobic region is highly variable among identified Gap-like (GPL, peptidoglycolipid, addressing protein) proteins and may be involved in substrate recognition. SAP also belongs to the LysE protein superfamily (pfam01810), whose members have been implicated in small molecule transport in bacteria. Other Gap proteins export metabolites across the cell membrane so it is possible that Sap specifically may be involved in transport of sulfolipid-1 across the membrane.	5.72001e-23
NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0
NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0

Protein sequences

>NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein
MIGKPLSRPGFVIVVVVVASVAMWGTVLVLGLVATADPVRIGISVLLSSQPRAVGQLVAFWLGGIFTSVALATGVLFGLRGFALDVMHRVEVATASSTAGHIQIAMGVTALLIAALAIRLSPGQRIRLGMTGANPSQLQVRTSMTISRLSTRAQFALQARPLRVAFVLGVGMLADLRFLVALTAILASGAAVATQVTAAGVYTLVALTFVELPLASQLAAPAKTGQIMSVLQRWVKARRHQIFAVVIALLGAFLMTRGMGRV
>NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C
MSRREFFAKLTGAGAAALLMDFAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYFGTLSSTRGFNDPSPAYQQKGWNPMTQALDPAGITIPFRLDTTRGPILDGECVNDPDHAWIAMHNSWNNGGNDNWLPAQSATRTGPYVPMVMGYYTRQDIPIHHLLADTFTICDGYHCSLLGGTLPNRLYWMSATIDPAGTNGGPQLVEPGFLPEQQYSWRIMPENLEDAGISWKVYQSKDAGRFINTPISNNGLVQAFRQSANPRSNLARFGIAPTYPLDFAADVKGNRLPQVSWLVPPFIQSEHPALPVALGAVAMVNALRILLSNPAVWEKTALIISYDENGGFFDHVTPPTAPPGTPGEYVTVPDINAVTGSGGIRGPIGLGFRVPCLVISPFSRGGLMVHDTFDHTSQLKLIRARFGVPIPNLTAWRDGVVGDMTSAFNFATPPNPTRPNLSHPLLAAVPKLPQCIPNVVLGTTDGTLPAIPYRVPYPQIMPTQESSPTRGIPSGLC
>NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C
MTRRQFFAKAAAATTAGALTSLAAPIIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYFGTLSGTRGFNDPSPAFAQKGWNPATQAVDPAGTTIPFRFDTTRGPLLDGECVNDPDHGWIAMHNSWNGGANDGWLPAQAASSPLQGNVPVTMGYYTRRDLPIHYLLADTFTVCDAYYCSLLGGTTPNRLYWMSAWIDPDGTNGGPILIEPNIQPQQKLSWRIMPQNLEDAAVSWKVYQNKFLGPLNNTVVGYNGLINDFQQAADPRSNLARYGIAPTYPLDFAADVKNNALPKVSWVLPGFLLSEHPALPVSIGAVGIVDVLRILLSNPAVWEKTAVIVNYDENGGFFDHVTPPTPPPGTPGEYVTVPDINAVPGSGGIRGPIGLGFRTPCIVISPYSRGPLMVHDTFDHTSTLKLISARFGVPVPNLSAWRNGVVGDMTSTFNFAVPPNPSKPNLDHPLLKSVPKLPQCVPNAVLGTTTKTSIPYRVPFPQMMPTQETSPTRGIPSGVC
>NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C
MSRREFLAKATGAGAAAFLTDWAAPVIEKAYAAGPCSGHLTDIEHIVLCLQENRSFDHYFGTLSSVDGFDTPTPLFAQKGWNPQTQAVDPAGITLPYRIDTTRGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLAAQARTRSAANTPVVMGYYARPDIPIHYLLADTFTVCDHYHSSLLGGTMPNRLYWISGTVNPDGDQGGPQIVEPSIQPKLTFSWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKAAGDPRSDLARYGIAPTYPMDFVLDVINNRLPQVSWVVPLTVDSEHPSFPIAVGAVTIVNLIRTLLRNPAVWEKTALIIAYDEHGGFFDHVTPPTAPPGTPGEWIPNSVDINKVDGSGGIRGPIGLGYRVPCFVISPYSRGGLMVHDQFDHTSQLQLIGKRFGVPVPNLTPWRASLTGDMTSAFNFAAPPDPSRPNLDHPARQLPKVANCVPNVVLGFLNEGLPYRVPYPQTMPVQESGPVRGIPSGIC
>NZ_CP009483.1|WP_036393041.1|1051566_1051824_-|hypothetical-protein
MLGGLSVPLSWGTAVPPDDYDHWAKEDEAAEVAVVPGAVDPEPAESSTDEWDEWAEWNEWEAANAEPRFEVPRSSRVVPHSPAAG
>NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target
MATRFMTDPHAMRAMAGRFEVHAQTVEDEARRMWASSQNISGAGWSGLAEATSLDTMGQMNQAFRNIVNMLHGVRDGLIRDANNYEQQEQASQQILSS
>NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein
MTINYQFGDVDAHGATIRAQAASLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGSNMAQTDSAVGSSWA
>NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein
MRIARLLGVVLTVVTVGLAGGVLLAPPSAAQPPFRLPGYVTDNAGVLSGSDRAEVTSAINELYADRHIRLWVVYVDNFSGQSAMNWGQSTFRSSELGSYDALLAVATVARSYVFLVPSTVPDVSAGQVEELRRNQIEPALRSGDWGGAAVAAANGLNKSPSSSGRVTLLVALGVIVVAVVILLVVTRYRARRRRADALAAARRVDPTDQRALAAVPPDILDDLSRSMVVAVDNAVRTSSNELAVAIDEFGQERTAPFTRAVDNAKAALAQAFSVRQQLDDSVPETPAQRRELLTRVIVSAATADRELEAQTEAFEQLRDLVINAPSRLDMLTQQYVELTTRIAPSQQRLAELHDEFGETALTSVAGNVTAAQERLVFADRNIGMARELSTQAVSGGQSGLVDAVRAAESALGQARSLLDAVDSAAGDIRHAVTELPSVLADVTAGIKQADEQLQKTPGSTSAHTRELVAARDAAAQALEESRNTRGTGVADPLGTFARVSKAGADLDRVLTTVAQEQANAERLNRSFEQALFTAESRVRAVSDYIDTRRGSIGPEARTRLAEAKRQLHAARDKRSTNVTEAVGHANAASTLAANAQALANADVQAAQRAYTRQGGDNAGAILGGIIIGNLLSGGLRGGFGGWSPTSFGGSSSSSSGSSGGGFMGGGGRF
>NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase
MTTNQQDPYGDFDRQRRVAEPPKSAGLPGTEGQHRTDFARDRARVLHSAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDPDLVELAGLAHDIGHPPYGHNGERALDDVAACCGGFEGNAQNFRILTSLEPKVLDSQGLSAGLNLTRAALDAVTKYPWTRGDGRRKFGFYEEDQQPAAWVRTGAPADRPCLEAQVMDWADDVAYSVHDVEDGVVSERIDLRVLADHDDAAALARLGQSEFRRLGADELMAAARRLSALPVVAAVGKYDATLAASVALKRLTSELVGRFASAAIATTRAVAGSGPLTRYQAELQIPDLVRAEVAVLKILALQFIMSDPRHLEAQARQRERIHRVAQWLSSGAPRTLDPVFAAAYHTADDDAARMRVIVDQIASYTEGRLERIDAGQFPGRTTVLH
>NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase
MSSPAGRSRISDRDIAAIRDGARIEDVVGDYVQLRRAGADSLRGLCPFHNEKSPSFHVRPNHGHFHCFGCGEGGDVYAFIQKIEHVSFVEAVELLADRIGYTISYTGAATSVQRDRGSRSRLLAANAAAAEFYAVALESDEAAPARHYLTQRNFDAQAARRFGCGFAPSGWDSLTKHLQRKGFEFKELEAAGLSRQGRHGPMDRFHRRLLWPIRSSAGEVIGFGARRLFDDDPMEAKYVNTPETLLYKKSSVMFGIDLAKRDIAKGHQAVVVEGYTDVMAMHLAGVTTAVASCGTAFGDEHLAMLRRLMMDDSFFRGELIYVFDGDAAGRAAALKALDGEQNLAGQSFVAVAPDGMDPCDLRLASGDAALRDLVARRTPLFEFAIRSALAETDLNSAEGRVAALRRCVPMVGQIKDPMLRDEYARQLAGWVGWDDVAQVVDRVRSQAKTPAKVPGRGHPGSKAPRRATQQPPDAPSAEPAAARPDPRDPTLWPQREALKSALQYPALAGPVFDTLTVESFTHPGYCAVRAAIEAAGGTSAGVTGAQWMDMVARQTTSPLTTGLINELAVEAIAVDDDKLPRYIGGVLARLQEVWMGRQIAEVKSKLQRMSPIEHGDEYHALFGDLVAMEAYRRSLLEQASGNDLTA
>NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase
MASVIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVITSRDDVVGIDSSIILPREVWVASGHVEVFHDPLVESLITHKRYRADHLIEAYEAKHGHPPPNGLADIRDPDTGEPGQWTEPREFNMMLKTYLGPIETEEGLHYLRPETAQGIFINFANVVTTSRKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWYVELGIDPQNLRLWEHPKEKLSHYSDRTVDIEYKFGFLGNPWGELEGVANRTDFDLSTHSKHSGTDLNFYDQVNDTRYTPYVIEPAAGLTRSFMAFLIDAYSEDEAPNAKGVMEKRTVLRLDARLAPVKAAVLPLSRHADLSPKARDLAAELRTCWNIEFDDAGAIGRRYRRQDEIGTPYCVTVDFDSLEDNAVTVRERDAMTQERIAIDKVADYLAVRLKGCC
>NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator
MATSPATPVAVDDLVGHHEHGARSSSGHPASPAPPPREILDAAGELLRALAAPVRIAIVLQLRESQRCVHELVDALGVPQPLVSQHLKILKAAGVVTGERSGREVLYRLADHHLAHIVVDAVAHASEESP
>NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor
MTGPSVRSTRQRAAISTLLETVDDFRSAQELHDELRRRGENIGLTTVYRTLQSMAAAGVVDTLRTDTGESVYRRCSEHHHHHLVCRSCGSTIEVADHEVEAWAAEVAARHGFSDVSHTIEIFGNCADCRS
>NZ_CP009483.1|WP_023365627.1|1066958_1067408_-|hypothetical-protein
MPSLQQRLASILPDVLSVEQEPDGAMTVRHSGTFASLRVVSIAEGLELVSLTQILAWDLPLTRKIRERAAKQARDVNFGAVTVLEKSPDNGTAKGAAKTAAKTASKTGDVMLRYNFPGAGLSDDALRTLILLVLDTGVQVRDALIAGAR
>NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase
MAKKAERTLTSADFPQLPPAPDDYPTFPDTSTWPVVFPALPPSPDGGPRRPPQHISKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLRRTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSAEEVRFLMGFNRDVVRRRRENLKEMGVRIRWVGSRPRLWRSVINELAVAEQMTKYNDVITINYCVNYGGRTEIADATRQIAREVAAGRLNPERISESTISRYMQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGSA
>NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO
MRLYRDRAVVLRQHKLGEADRIVTLLTRDHGLVRAVAKGVRRTRSKFGARLEPFAHIDAQLHPGRNLDIVTQVVSVDAFATDIVNDYGRYTCGCAMLETAERLAGEERAPAPALHRLTVGALRAVADGRRPRDLLLDAYLLRAMGIAGWAPALTECARCATPGPHRAFHIAAGGSVCAHCRPAGATTPPLGVLELMSALHDGDWAAAEQAPQSHRGYVSGLVAAHLQWHLERQLKTLPLVERTYRIDHTIAERRAALTRQVGECG
>NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase
MVGASESASGAVSGSGNQRLPTLTDLLYQLANGSVTSVDLVRRSLREIQASQSTLNAFRVVFTESALADAAAADRRRAAGDTGPLLGIPIAVKDDVDVAGVPTAYGTEGYVAPATADSEVVRRLKAAGAVIVGKTNTCELGQWPFTSGPGFGHTRNPWARRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRVPAAWTHLVGIKPQRGRISTWPLPEAFNGITVNGVLARTVADAALVLDAASGNVEGDLHRPPPVTASDYVGIAPGPLKIALSTRAPFNGFRAKLHPEILAATRQVGEQLQLLGHTVVRGNPDYSVQMSWDFLARSTAGLWEWAQRLGDDVTLDPRTVSNLRTGHMLSQAILRSARRHEAAAHRRVGSIFDIVDVVLAPTTALPPPLARAFDQMGGLATDRAIIAACPYTWPWNLLGWPAINVPAGFTVEGLPIGVQLMGPANSEGMLISLAAELEAVSGWAAKQPTVWWNEGTDTPAPHSVRPPQRWQR
>NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era
MTAEFRSGFVCLVGRPNTGKSTLTNALVGAKVAITSMRPQTTRHTIRGIVHRENFQIILVDTPGLHRPRTLLGKRLNDLVRATYAEVDVIGLCIPADEAIGPGDRWILEQIRSVAPGTTLVVIVTKIDKVPKDRVAAQLVAVGELVENLPGSTEIVPVSAVTGAQVDVLVDVLAGALPPGPAYYPDGELTDEPEEVLMAEFIREAALEGVHDELPHSLAVVIDDVSPRDGRDDLIDVHAVVYVERDSQKGIVIGKGGARLRQVGTAARGQIEKLLGTKVYLDLRVKVAKNWQRDPKQLGRLGF
>NZ_CP009483.1|WP_036393017.1|1071595_1071916_-|hypothetical-protein
MAEPADPEDAKLVMLARAAMARAGADSGAAVRDHEGRTYVAVPVNLPALRLTGLQAAVAAAVSSGAIGLEAAALVAGSVDDPGIAALRELSPMAVVVVTDSTGTPL
>NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter
MTGLAQLLGAIVLIGLGGVFAALDAAFSTVSLARVQELVREARPGAVALLKVMVERPRYINLVVLLRIVCEITATAFLVVFFRHNLNLNGGLFVAAAVMVVTSFVVIGVGPRTLGRQHAYSIALATAVPLQVISWLLMPISRLLVLLGNALTPGRGFRNGPFASEVELREVVDLAQQRGVVAADERKMIESVFELGDTPAREVMVPRTEMIWIEGDKSPAQAMNLAVRSGHSRIPVIGENVDDILGVVYLKDLVRQTFFSPGGGRESTVADVMRPAVFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDEAEIAPVEDLGDKRFRVSARLPIEDVGELYGMDFDGDLDVDTVGGLLALELGRVPLPGAEVVSHGLRLQAEGGRDHRGRMRIGTVLVSPVELGETVATDCSGYRPDEGDSDG

Crispr_ID: NZ_CP009483_5

• CRISPR_ID: NZ_CP009483_5
• CRISPR_location: 1061981-1062378
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP009483_5

Consensus_repeat	Method
CCGATATTGCCGCTGCCCACGTT	CRISPRCasFinder

spacers of NZ_CP009483_5

>5.1|1062004|22|NZ_CP009483|CRISPRCasFinder
ACCGAAGCCGACGTTGCTACTC
>5.2|1062049|37|NZ_CP009483|CRISPRCasFinder
GAAGTTACCACCATTACCGTTGCCGAAATTCGTGTCG
>5.3|1062109|37|NZ_CP009483|CRISPRCasFinder
GGTGTTGCCGATATTTCCACCACCCAGATTGGTGCTA
>5.4|1062169|22|NZ_CP009483|CRISPRCasFinder
CTGGCTGCCGAAGTTTCCGCTA
>5.5|1062214|37|NZ_CP009483|CRISPRCasFinder
GCCGCTGCCCAGGTTGATGTCGCCCCGGTTTCCGCCA
>5.6|1062274|22|NZ_CP009483|CRISPRCasFinder
GCCGCTGCCCAAGTTGAACGAG
>5.7|1062319|37|NZ_CP009483|CRISPRCasFinder
CGTGTCACCGATGTTGCCGCTACCCAGGTTGAGCGAG

CRISPR arrays and Neighbor proteins around NZ_CP009483_5

CRISPR arrays

The CRISPR arrays of NZ_CP009483_5

>merge|NZ_CP009483|5|1061981-1062378|CRISPRCasFinder
CCGAAATTGCCATTCCCGGTGTTACCGAAGCCGACGTTGCTACTCCCGGAATTTCCGCTGCCGAAATTGAAGTTACCACCATTACCGTTGCCGAAATTCGTGTCGCCGATATTGCCGCTGCCCACGTTGGTGTTGCCGATATTTCCACCACCCAGATTGGTGCTACCGATATTGCCGCTGCCCAGGTTCTGGCTGCCGAAGTTTCCGCTACCGACGTTGAAGTTGCCGACGTTGCCGCTGCCCAGGTTGATGTCGCCCCGGTTTCCGCCACCGATGTTGGTGCTGCCGATATTGCCGCTGCCCAAGTTGAACGAGCCGACGTTGCCGCTTCCGATGTTCGTGTCACCGATGTTGCCGCTACCCAGGTTGAGCGAGCCGATGTTGCCGAAACCGAAGTT

>NZ_CP009483|5|5|1061981-1062378|CRISPRCasFinder
CCGAAATTGCCATTCCCGGTGTT	ACCGAAGCCGACGTTGCTACTC
CCGGAATTTCCGCTGCCGAAATT	GAAGTTACCACCATTACCGTTGCCGAAATTCGTGTCG
CCGATATTGCCGCTGCCCACGTT	GGTGTTGCCGATATTTCCACCACCCAGATTGGTGCTA
CCGATATTGCCGCTGCCCAGGTT	CTGGCTGCCGAAGTTTCCGCTA
CCGACGTTGAAGTTGCCGACGTT	GCCGCTGCCCAGGTTGATGTCGCCCCGGTTTCCGCCA
CCGATGTTGGTGCTGCCGATATT	GCCGCTGCCCAAGTTGAACGAG
CCGACGTTGCCGCTTCCGATGTT	CGTGTCACCGATGTTGCCGCTACCCAGGTTGAGCGAG
CCGATGTTGCCGAAACCGAAGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_036393041.1|1051566_1051824_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase	unknown	unknown	gnl|CDD|235686
NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|377587
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase	unknown	unknown	gnl|CDD|173288
NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein	unknown	unknown	gnl|CDD|377378
NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO	unknown	unknown	gnl|CDD|234622
NZ_CP009483.1|WP_036393017.1|1071595_1071916_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase	unknown	unknown	gnl|CDD|235551
NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein	unknown	unknown	gnl|CDD|377587
NZ_CP009483.1|WP_023365627.1|1066958_1067408_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era	unknown	unknown	gnl|CDD|234624
NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein	unknown	unknown	gnl|CDD|378566
NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase	unknown	unknown	gnl|CDD|235240
NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|235098

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	4.4e-19	63.7	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein	gnl|CDD|377378	pfam04536, TPM_phosphatase, TPM domain. This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II.	1.67335e-20
NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase	gnl|CDD|235686	PRK06061, PRK06061, amidase; Provisional.	0
NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	3.26736e-11
NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	1.22235e-18
NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase	gnl|CDD|173288	PRK14827, PRK14827, undecaprenyl pyrophosphate synthase; Provisional.	0
NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era	gnl|CDD|234624	PRK00089, era, GTPase Era; Reviewed.	3.57123e-165
NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase	gnl|CDD|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0
NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0
NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	5.70515e-10
NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO	gnl|CDD|234622	PRK00085, recO, DNA repair protein RecO; Reviewed.	6.40078e-88
NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	2.89137e-115
NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	8.06071e-47
NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein	gnl|CDD|378566	pfam11139, SfLAP, Sap, sulfolipid-1-addressing protein. SAP is a transmembrane transport protein with six predicted transmembrane helices, with a hydrophilic domain between helices 3 and 4. This hyrodphobic region is highly variable among identified Gap-like (GPL, peptidoglycolipid, addressing protein) proteins and may be involved in substrate recognition. SAP also belongs to the LysE protein superfamily (pfam01810), whose members have been implicated in small molecule transport in bacteria. Other Gap proteins export metabolites across the cell membrane so it is possible that Sap specifically may be involved in transport of sulfolipid-1 across the membrane.	5.72001e-23
NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0
NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0

Protein sequences

>NZ_CP009483.1|WP_023365611.1|1057986_1058775_+|GAP-family-protein
MIGKPLSRPGFVIVVVVVASVAMWGTVLVLGLVATADPVRIGISVLLSSQPRAVGQLVAFWLGGIFTSVALATGVLFGLRGFALDVMHRVEVATASSTAGHIQIAMGVTALLIAALAIRLSPGQRIRLGMTGANPSQLQVRTSMTISRLSTRAQFALQARPLRVAFVLGVGMLADLRFLVALTAILASGAAVATQVTAAGVYTLVALTFVELPLASQLAAPAKTGQIMSVLQRWVKARRHQIFAVVIALLGAFLMTRGMGRV
>NZ_CP009483.1|WP_036393039.1|1055850_1057386_-|phospholipase-C
MSRREFFAKLTGAGAAALLMDFAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYFGTLSSTRGFNDPSPAYQQKGWNPMTQALDPAGITIPFRLDTTRGPILDGECVNDPDHAWIAMHNSWNNGGNDNWLPAQSATRTGPYVPMVMGYYTRQDIPIHHLLADTFTICDGYHCSLLGGTLPNRLYWMSATIDPAGTNGGPQLVEPGFLPEQQYSWRIMPENLEDAGISWKVYQSKDAGRFINTPISNNGLVQAFRQSANPRSNLARFGIAPTYPLDFAADVKGNRLPQVSWLVPPFIQSEHPALPVALGAVAMVNALRILLSNPAVWEKTALIISYDENGGFFDHVTPPTAPPGTPGEYVTVPDINAVTGSGGIRGPIGLGFRVPCLVISPFSRGGLMVHDTFDHTSQLKLIRARFGVPIPNLTAWRDGVVGDMTSAFNFATPPNPTRPNLSHPLLAAVPKLPQCIPNVVLGTTDGTLPAIPYRVPYPQIMPTQESSPTRGIPSGLC
>NZ_CP009483.1|WP_023365606.1|1054103_1055636_-|phospholipase-C
MTRRQFFAKAAAATTAGALTSLAAPIIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYFGTLSGTRGFNDPSPAFAQKGWNPATQAVDPAGTTIPFRFDTTRGPLLDGECVNDPDHGWIAMHNSWNGGANDGWLPAQAASSPLQGNVPVTMGYYTRRDLPIHYLLADTFTVCDAYYCSLLGGTTPNRLYWMSAWIDPDGTNGGPILIEPNIQPQQKLSWRIMPQNLEDAAVSWKVYQNKFLGPLNNTVVGYNGLINDFQQAADPRSNLARYGIAPTYPLDFAADVKNNALPKVSWVLPGFLLSEHPALPVSIGAVGIVDVLRILLSNPAVWEKTAVIVNYDENGGFFDHVTPPTPPPGTPGEYVTVPDINAVPGSGGIRGPIGLGFRTPCIVISPYSRGPLMVHDTFDHTSTLKLISARFGVPVPNLSAWRNGVVGDMTSTFNFAVPPNPSKPNLDHPLLKSVPKLPQCVPNAVLGTTTKTSIPYRVPFPQMMPTQETSPTRGIPSGVC
>NZ_CP009483.1|WP_036393202.1|1052184_1053711_-|phospholipase-C
MSRREFLAKATGAGAAAFLTDWAAPVIEKAYAAGPCSGHLTDIEHIVLCLQENRSFDHYFGTLSSVDGFDTPTPLFAQKGWNPQTQAVDPAGITLPYRIDTTRGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLAAQARTRSAANTPVVMGYYARPDIPIHYLLADTFTVCDHYHSSLLGGTMPNRLYWISGTVNPDGDQGGPQIVEPSIQPKLTFSWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKAAGDPRSDLARYGIAPTYPMDFVLDVINNRLPQVSWVVPLTVDSEHPSFPIAVGAVTIVNLIRTLLRNPAVWEKTALIIAYDEHGGFFDHVTPPTAPPGTPGEWIPNSVDINKVDGSGGIRGPIGLGYRVPCFVISPYSRGGLMVHDQFDHTSQLQLIGKRFGVPVPNLTPWRASLTGDMTSAFNFAAPPDPSRPNLDHPARQLPKVANCVPNVVLGFLNEGLPYRVPYPQTMPVQESGPVRGIPSGIC
>NZ_CP009483.1|WP_036393041.1|1051566_1051824_-|hypothetical-protein
MLGGLSVPLSWGTAVPPDDYDHWAKEDEAAEVAVVPGAVDPEPAESSTDEWDEWAEWNEWEAANAEPRFEVPRSSRVVPHSPAAG
>NZ_CP009483.1|WP_036393043.1|1051122_1051419_-|WXG100-family-type-VII-secretion-target
MATRFMTDPHAMRAMAGRFEVHAQTVEDEARRMWASSQNISGAGWSGLAEATSLDTMGQMNQAFRNIVNMLHGVRDGLIRDANNYEQQEQASQQILSS
>NZ_CP009483.1|WP_023363993.1|1050799_1051084_-|hypothetical-protein
MTINYQFGDVDAHGATIRAQAASLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGSNMAQTDSAVGSSWA
>NZ_CP009483.1|WP_023365598.1|1048594_1050604_+|TPM-domain-containing-protein
MRIARLLGVVLTVVTVGLAGGVLLAPPSAAQPPFRLPGYVTDNAGVLSGSDRAEVTSAINELYADRHIRLWVVYVDNFSGQSAMNWGQSTFRSSELGSYDALLAVATVARSYVFLVPSTVPDVSAGQVEELRRNQIEPALRSGDWGGAAVAAANGLNKSPSSSGRVTLLVALGVIVVAVVILLVVTRYRARRRRADALAAARRVDPTDQRALAAVPPDILDDLSRSMVVAVDNAVRTSSNELAVAIDEFGQERTAPFTRAVDNAKAALAQAFSVRQQLDDSVPETPAQRRELLTRVIVSAATADRELEAQTEAFEQLRDLVINAPSRLDMLTQQYVELTTRIAPSQQRLAELHDEFGETALTSVAGNVTAAQERLVFADRNIGMARELSTQAVSGGQSGLVDAVRAAESALGQARSLLDAVDSAAGDIRHAVTELPSVLADVTAGIKQADEQLQKTPGSTSAHTRELVAARDAAAQALEESRNTRGTGVADPLGTFARVSKAGADLDRVLTTVAQEQANAERLNRSFEQALFTAESRVRAVSDYIDTRRGSIGPEARTRLAEAKRQLHAARDKRSTNVTEAVGHANAASTLAANAQALANADVQAAQRAYTRQGGDNAGAILGGIIIGNLLSGGLRGGFGGWSPTSFGGSSSSSSGSSGGGFMGGGGRF
>NZ_CP009483.1|WP_023365596.1|1047188_1048472_-|deoxyguanosinetriphosphate-triphosphohydrolase
MTTNQQDPYGDFDRQRRVAEPPKSAGLPGTEGQHRTDFARDRARVLHSAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDPDLVELAGLAHDIGHPPYGHNGERALDDVAACCGGFEGNAQNFRILTSLEPKVLDSQGLSAGLNLTRAALDAVTKYPWTRGDGRRKFGFYEEDQQPAAWVRTGAPADRPCLEAQVMDWADDVAYSVHDVEDGVVSERIDLRVLADHDDAAALARLGQSEFRRLGADELMAAARRLSALPVVAAVGKYDATLAASVALKRLTSELVGRFASAAIATTRAVAGSGPLTRYQAELQIPDLVRAEVAVLKILALQFIMSDPRHLEAQARQRERIHRVAQWLSSGAPRTLDPVFAAAYHTADDDAARMRVIVDQIASYTEGRLERIDAGQFPGRTTVLH
>NZ_CP009483.1|WP_023365594.1|1045231_1047172_-|DNA-primase
MSSPAGRSRISDRDIAAIRDGARIEDVVGDYVQLRRAGADSLRGLCPFHNEKSPSFHVRPNHGHFHCFGCGEGGDVYAFIQKIEHVSFVEAVELLADRIGYTISYTGAATSVQRDRGSRSRLLAANAAAAEFYAVALESDEAAPARHYLTQRNFDAQAARRFGCGFAPSGWDSLTKHLQRKGFEFKELEAAGLSRQGRHGPMDRFHRRLLWPIRSSAGEVIGFGARRLFDDDPMEAKYVNTPETLLYKKSSVMFGIDLAKRDIAKGHQAVVVEGYTDVMAMHLAGVTTAVASCGTAFGDEHLAMLRRLMMDDSFFRGELIYVFDGDAAGRAAALKALDGEQNLAGQSFVAVAPDGMDPCDLRLASGDAALRDLVARRTPLFEFAIRSALAETDLNSAEGRVAALRRCVPMVGQIKDPMLRDEYARQLAGWVGWDDVAQVVDRVRSQAKTPAKVPGRGHPGSKAPRRATQQPPDAPSAEPAAARPDPRDPTLWPQREALKSALQYPALAGPVFDTLTVESFTHPGYCAVRAAIEAAGGTSAGVTGAQWMDMVARQTTSPLTTGLINELAVEAIAVDDDKLPRYIGGVLARLQEVWMGRQIAEVKSKLQRMSPIEHGDEYHALFGDLVAMEAYRRSLLEQASGNDLTA
>NZ_CP009483.1|WP_036393019.1|1064513_1065896_-|glycine--tRNA-ligase
MASVIDTVVNLAKRRGFVYPSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVITSRDDVVGIDSSIILPREVWVASGHVEVFHDPLVESLITHKRYRADHLIEAYEAKHGHPPPNGLADIRDPDTGEPGQWTEPREFNMMLKTYLGPIETEEGLHYLRPETAQGIFINFANVVTTSRKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDTRLQWYVELGIDPQNLRLWEHPKEKLSHYSDRTVDIEYKFGFLGNPWGELEGVANRTDFDLSTHSKHSGTDLNFYDQVNDTRYTPYVIEPAAGLTRSFMAFLIDAYSEDEAPNAKGVMEKRTVLRLDARLAPVKAAVLPLSRHADLSPKARDLAAELRTCWNIEFDDAGAIGRRYRRQDEIGTPYCVTVDFDSLEDNAVTVRERDAMTQERIAIDKVADYLAVRLKGCC
>NZ_CP009483.1|WP_023365623.1|1066099_1066492_+|ArsR-family-transcriptional-regulator
MATSPATPVAVDDLVGHHEHGARSSSGHPASPAPPPREILDAAGELLRALAAPVRIAIVLQLRESQRCVHELVDALGVPQPLVSQHLKILKAAGVVTGERSGREVLYRLADHHLAHIVVDAVAHASEESP
>NZ_CP009483.1|WP_023365625.1|1066488_1066881_+|transcriptional-repressor
MTGPSVRSTRQRAAISTLLETVDDFRSAQELHDELRRRGENIGLTTVYRTLQSMAAAGVVDTLRTDTGESVYRRCSEHHHHHLVCRSCGSTIEVADHEVEAWAAEVAARHGFSDVSHTIEIFGNCADCRS
>NZ_CP009483.1|WP_023365627.1|1066958_1067408_-|hypothetical-protein
MPSLQQRLASILPDVLSVEQEPDGAMTVRHSGTFASLRVVSIAEGLELVSLTQILAWDLPLTRKIRERAAKQARDVNFGAVTVLEKSPDNGTAKGAAKTAAKTASKTGDVMLRYNFPGAGLSDDALRTLILLVLDTGVQVRDALIAGAR
>NZ_CP009483.1|WP_036392649.1|1067407_1068301_-|decaprenyl-diphosphate-synthase
MAKKAERTLTSADFPQLPPAPDDYPTFPDTSTWPVVFPALPPSPDGGPRRPPQHISKAAAPRIPADRLPNHVAIVMDGNGRWATQRGLRRTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSAEEVRFLMGFNRDVVRRRRENLKEMGVRIRWVGSRPRLWRSVINELAVAEQMTKYNDVITINYCVNYGGRTEIADATRQIAREVAAGRLNPERISESTISRYMQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGSA
>NZ_CP009483.1|WP_036392645.1|1068293_1069091_-|DNA-repair-protein-RecO
MRLYRDRAVVLRQHKLGEADRIVTLLTRDHGLVRAVAKGVRRTRSKFGARLEPFAHIDAQLHPGRNLDIVTQVVSVDAFATDIVNDYGRYTCGCAMLETAERLAGEERAPAPALHRLTVGALRAVADGRRPRDLLLDAYLLRAMGIAGWAPALTECARCATPGPHRAFHIAAGGSVCAHCRPAGATTPPLGVLELMSALHDGDWAAAEQAPQSHRGYVSGLVAAHLQWHLERQLKTLPLVERTYRIDHTIAERRAALTRQVGECG
>NZ_CP009483.1|WP_036392642.1|1069152_1070661_+|amidase
MVGASESASGAVSGSGNQRLPTLTDLLYQLANGSVTSVDLVRRSLREIQASQSTLNAFRVVFTESALADAAAADRRRAAGDTGPLLGIPIAVKDDVDVAGVPTAYGTEGYVAPATADSEVVRRLKAAGAVIVGKTNTCELGQWPFTSGPGFGHTRNPWARRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRVPAAWTHLVGIKPQRGRISTWPLPEAFNGITVNGVLARTVADAALVLDAASGNVEGDLHRPPPVTASDYVGIAPGPLKIALSTRAPFNGFRAKLHPEILAATRQVGEQLQLLGHTVVRGNPDYSVQMSWDFLARSTAGLWEWAQRLGDDVTLDPRTVSNLRTGHMLSQAILRSARRHEAAAHRRVGSIFDIVDVVLAPTTALPPPLARAFDQMGGLATDRAIIAACPYTWPWNLLGWPAINVPAGFTVEGLPIGVQLMGPANSEGMLISLAAELEAVSGWAAKQPTVWWNEGTDTPAPHSVRPPQRWQR
>NZ_CP009483.1|WP_023365635.1|1070687_1071599_-|GTPase-Era
MTAEFRSGFVCLVGRPNTGKSTLTNALVGAKVAITSMRPQTTRHTIRGIVHRENFQIILVDTPGLHRPRTLLGKRLNDLVRATYAEVDVIGLCIPADEAIGPGDRWILEQIRSVAPGTTLVVIVTKIDKVPKDRVAAQLVAVGELVENLPGSTEIVPVSAVTGAQVDVLVDVLAGALPPGPAYYPDGELTDEPEEVLMAEFIREAALEGVHDELPHSLAVVIDDVSPRDGRDDLIDVHAVVYVERDSQKGIVIGKGGARLRQVGTAARGQIEKLLGTKVYLDLRVKVAKNWQRDPKQLGRLGF
>NZ_CP009483.1|WP_036393017.1|1071595_1071916_-|hypothetical-protein
MAEPADPEDAKLVMLARAAMARAGADSGAAVRDHEGRTYVAVPVNLPALRLTGLQAAVAAAVSSGAIGLEAAALVAGSVDDPGIAALRELSPMAVVVVTDSTGTPL
>NZ_CP009483.1|WP_023365639.1|1071908_1073240_-|HlyC/CorC-family-transporter
MTGLAQLLGAIVLIGLGGVFAALDAAFSTVSLARVQELVREARPGAVALLKVMVERPRYINLVVLLRIVCEITATAFLVVFFRHNLNLNGGLFVAAAVMVVTSFVVIGVGPRTLGRQHAYSIALATAVPLQVISWLLMPISRLLVLLGNALTPGRGFRNGPFASEVELREVVDLAQQRGVVAADERKMIESVFELGDTPAREVMVPRTEMIWIEGDKSPAQAMNLAVRSGHSRIPVIGENVDDILGVVYLKDLVRQTFFSPGGGRESTVADVMRPAVFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDEAEIAPVEDLGDKRFRVSARLPIEDVGELYGMDFDGDLDVDTVGGLLALELGRVPLPGAEVVSHGLRLQAEGGRDHRGRMRIGTVLVSPVELGETVATDCSGYRPDEGDSDG

Crispr_ID: NZ_CP009483_6

• CRISPR_ID: NZ_CP009483_6
• CRISPR_location: 1524793-1524913
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP009483_6

Consensus_repeat	Method
GGCGGCGCAGGCGGCAACGGCGGAG	CRISPRCasFinder

spacers of NZ_CP009483_6

>6.1|1524818|23|NZ_CP009483|CRISPRCasFinder
TACCGGCCGGCAACGGCGGCGCA
>6.2|1524866|23|NZ_CP009483|CRISPRCasFinder
AGGGTGCCGGCGACGGTATCCCG

CRISPR arrays and Neighbor proteins around NZ_CP009483_6

CRISPR arrays

The CRISPR arrays of NZ_CP009483_6

>merge|NZ_CP009483|6|1524793-1524913|CRISPRCasFinder
GATCCCCCTGGCGGCCACGGCGGACTACCGGCCGGCAACGGCGGCGCAGGCGGCAACGGCGGAGCCGGCGGCAAGGGTGCCGGCGACGGTATCCCGGGCGGCGCAGGCGGAAACGGCGGAG

>NZ_CP009483|6|6|1524793-1524913|CRISPRCasFinder
GATCCCCCTGGCGGCCACGGCGGAC	TACCGGCCGGCAACGGCGGCGCA
GGCGGCAACGGCGGAGCCGGCGGCA	AGGGTGCCGGCGACGGTATCCCG
GGCGGCGCAGGCGGAAACGGCGGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023366440.1|1537515_1538688_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl|CDD|236947
NZ_CP009483.1|WP_023366404.1|1512630_1513347_-|siderophore-interacting-protein	unknown	unknown	gnl|CDD|99790
NZ_CP009483.1|WP_023366414.1|1518601_1522006_+|nuclease	unknown	unknown	gnl|CDD|225160
NZ_CP009483.1|WP_023366436.1|1535027_1536017_-|malate-dehydrogenase	unknown	unknown	gnl|CDD|235468
NZ_CP009483.1|WP_023366397.1|1510726_1511308_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP009483.1|WP_023366408.1|1514564_1516277_-|cold-shock-protein	unknown	unknown	gnl|CDD|236941
NZ_CP009483.1|WP_080674206.1|1539521_1540373_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP009483.1|WP_023366430.1|1531069_1531921_-|hypothetical-protein	unknown	unknown	gnl|CDD|270324
NZ_CP009483.1|WP_023366424.1|1525421_1526177_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023366416.1|1522090_1522558_-|hypothetical-protein	unknown	unknown	gnl|CDD|119360
NZ_CP009483.1|WP_023366428.1|1530129_1530963_+|acetoin-dehydrogenase	unknown	unknown	gnl|CDD|235628
NZ_CP009483.1|WP_042311916.1|1511839_1512541_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023366420.1|1522759_1524541_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP009483.1|WP_036392488.1|1517827_1518424_+|LppP/LprE-family-lipoprotein	unknown	unknown	gnl|CDD|379436
NZ_CP009483.1|WP_023366432.1|1531917_1533135_-|NADP-dependent-malic-enzyme	unknown	unknown	gnl|CDD|223358
NZ_CP009483.1|WP_023366426.1|1526362_1530052_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	unknown	unknown	gnl|CDD|237030
NZ_CP009483.1|WP_023366438.1|1536223_1537324_+|magnesium-and-cobalt-transport-protein-CorA	unknown	unknown	gnl|CDD|213364
NZ_CP009483.1|WP_023366442.1|1538692_1539532_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP009483.1|WP_023366406.1|1513428_1514568_-|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_CP009483.1|WP_036392490.1|1516894_1517416_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023366440.1|1537515_1538688_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl|CDD|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
NZ_CP009483.1|WP_023366404.1|1512630_1513347_-|siderophore-interacting-protein	gnl|CDD|99790	cd06193, siderophore_interacting, Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from transferrin and lactoferrin for bacterial uptake, contributing to pathogen virulence. Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport mechanism of photosystem I. FNR transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) and then transfers a hydride ion to convert NADP+ to NADPH. FNR has since been shown to utilize a variety of electron acceptors and donors and has a variety of physiological functions including nitrogen assimilation, dinitrogen fixation, steroid hydroxylation, fatty acid metabolism, oxygenase activity, and methane assimilation in a variety of organisms. FNR has an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) flavin sub-domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal moeity may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Because flavins such as FAD can exist in oxidized, semiquinone (one-electron reduced), or fully reduced hydroquinone forms, FNR can interact with one and two electron carriers. FNR has a strong preference for NADP(H) vs NAD(H).	7.66149e-49
NZ_CP009483.1|WP_023366414.1|1518601_1522006_+|nuclease	gnl|CDD|225160	COG2251, COG2251, Predicted nuclease (RecB family) [General function prediction only].	1.48017e-155
NZ_CP009483.1|WP_023366436.1|1535027_1536017_-|malate-dehydrogenase	gnl|CDD|235468	PRK05442, PRK05442, malate dehydrogenase; Provisional.	0
NZ_CP009483.1|WP_023366397.1|1510726_1511308_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	5.18498e-09
NZ_CP009483.1|WP_023366408.1|1514564_1516277_-|cold-shock-protein	gnl|CDD|236941	PRK11634, PRK11634, ATP-dependent RNA helicase DeaD; Provisional.	2.44414e-174
NZ_CP009483.1|WP_080674206.1|1539521_1540373_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.03568e-72
NZ_CP009483.1|WP_023366430.1|1531069_1531921_-|hypothetical-protein	gnl|CDD|270324	cd13606, PBP2_ProX_like, Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold. This group includes periplasmic substrate-binding component of ABC transport systems from gram-negative and -positive bacteria that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.77685e-42
NZ_CP009483.1|WP_023366416.1|1522090_1522558_-|hypothetical-protein	gnl|CDD|119360	cd06543, GH18_PF-ChiA-like, PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in archaea but also in eukaryotes and prokaryotes. PF-ChiA exhibits hydrolytic activity toward both colloidal and crystalline (beta/alpha) chitins at high temperature.	4.4828e-61
NZ_CP009483.1|WP_023366426.1|1526362_1530052_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0
NZ_CP009483.1|WP_023366428.1|1530129_1530963_+|acetoin-dehydrogenase	gnl|CDD|235628	PRK05855, PRK05855, SDR family oxidoreductase.	2.66916e-58
NZ_CP009483.1|WP_042311916.1|1511839_1512541_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.5915e-57
NZ_CP009483.1|WP_023366420.1|1522759_1524541_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.99381e-80
NZ_CP009483.1|WP_036392488.1|1517827_1518424_+|LppP/LprE-family-lipoprotein	gnl|CDD|379436	pfam14041, Lipoprotein_21, LppP/LprE lipoprotein. The family includes putative lipoproteins LppP and LprE from species of Mycobacterium. LppP is required for optimal growth of M. tuberculosis.	1.97503e-12
NZ_CP009483.1|WP_023366432.1|1531917_1533135_-|NADP-dependent-malic-enzyme	gnl|CDD|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	2.76337e-163
NZ_CP009483.1|WP_023366438.1|1536223_1537324_+|magnesium-and-cobalt-transport-protein-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.41352e-164
NZ_CP009483.1|WP_023366442.1|1538692_1539532_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.31538e-75
NZ_CP009483.1|WP_023366406.1|1513428_1514568_-|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	3.77163e-51

Protein sequences

>NZ_CP009483.1|WP_023366420.1|1522759_1524541_-|MFS-transporter
MTTATSRMPAASYSGSPWNALWSMMIGFFMIMLDSTIVAIANPTIMAVLHVGYATVVWVTSAYLLGFAVVLLVAGRLGDRFGPKNLYLTGLAVFTAASMWCGLSGSAGALITARVVQGVGAGLLTPQTLSIITRTFPAARRGVAMSMWGATAGVASLVGPLAGGALVGGLGWEWIFFVNIPIGVLGLALAAWLVPVLPVRAQRFDLIGVALSGIGMFLLVFGLQEGPSAGWQPWIWAVLVAGLGFMSAFVYWQSLNRHAPLIPLEIFRDRDFSLCTVGVAITAFATTAMMLPLIFYAQSVCGLSPIRAALLIAPVAISSGVLAPFVGRIVDTSHPLPVVGFGFSALAIAMTWLSIEMEPDTPVWRLVLPFCAIGVGMAFVWSPLAATATRNLRPDQAGASSGVYNATRQIGAVLGSASMAAFMTSRISAEMPPPPDGAPGFGGEGGGLQLPEFVRAPFSAAMSQSMLLPAFIALFGIVAALFLVGGTGATASRRLLPQGDHGDDYQESDEDFDDDDYVEYILQPEPDRWHRSDGEIPWAYRQSCGEPVDVPSDVVRNGSHIDSSPQTSTPSLLGSGQSAYRAHYLDDPHGPAG
>NZ_CP009483.1|WP_023366416.1|1522090_1522558_-|hypothetical-protein
MQADGTAAGNPVRVSFTLTVLPTGLTADGLRVVQNAIANGVDIGQVDVMAMDYDDPAFDYSGKMGDLAIQAAQRVHDQLAPLYPSKSDTQVWAMVGVTPMIGVNDDPREVFTVADADKLTAFARQKGLGRLAMWSANRDSQCPAELRNRRTRAAV
>NZ_CP009483.1|WP_023366414.1|1518601_1522006_+|nuclease
MFLSDDTLVYSASDLASAARCEYALLRDFDAKLGRGPAAPVADELLARAAVLGNEHERRRLDRLRDEFGDGVAVIGRPAYTLAGLTAAAAATRHAIANHARVVYQAALFDGRFVGFADFLIRDGERYRIADTKLARSPQVTALLQLAAYADALAGCGVPVAPEAELELGDGTVVRYRISDLIPVYRSQRAVLQRLLDNHYASGTAVCWDDPGVRACFRCPLCTEQLRATDDLLLVAGMRVTQREKLLDAGITTIDKLAEHTQPVPGLAPSVLGKLTAQAKLQVRQRNTGEPQYEIVDPQPLALLPEPDAGDLFFDFEGDPLWTADGHEWGLEYLFGVLEAGPAGAFQPLWAHDRAQERQALKDFLALVAKRRRRHPNMHIYHYAPYEKTALLRLAGRYGVGEDDIDELLRNGVLVDLYPLVRKSLRAGAESFSLKALEPLYMGARLRAGEVTTAADSITCYARYCDLRAEGCTDEAAAVLKEIEDYNHYDCRSTRELRDWLLMRAWEAGVTPIGVQPVADSGRVEDHDELAAALATFVGDDAATNRTPEQNVVALLSAARGYHRREDKPFWWGHFDRLNYPLDEWSDSTDVFVADETSVVAAWHTPARARKPQRRVRLTGGLARGDLKTSVFALYNPPAPPGISDDPDRRAAGHAEVVGVDDPGLPTEVVILERTGSDGNTFEQLPFALTPGPPVPTTVLRKSIEATASAVAGGLPRLPRTALVDVLLRHPPRTRLPRGTDIVADITVAVLGLDASYVAVHGPPGTGKTHTAARVIKRLVVEHSWRIGVVAQSHAAVENLLDCVIDADLDPGCVAKKKYDRTAPRWQQIDEKHYPAFIADHAGCVIGGTAWDFANEQRVPRGSLDLLVIDEAGQFSLANTIAVAPAATNMLLLGDPQQLPQVSQGTHPEPVDASALDWLVDGQRTLPDERGYFLDRSYRMHPAVCAAVSMLSYEGRLQSHAACTTARRVAGYQPGVHALSVAHQGNSIECPEEAEAILAEILALLGRSWSDERGTRPLAASDLLVLAPYNAQVGLLRQRLRSAGLDGIRVGTVDKFQGGQAPVVFISMTASSADDVPRGMSFLLNRNRLNVAISRAQYAAVVVRSEILTQYLPTTPAGLIDLGAFLALTSRPPP
>NZ_CP009483.1|WP_036392488.1|1517827_1518424_+|LppP/LprE-family-lipoprotein
MWSLPRRAAPLIGVSATALVAATLTGCGSGDSTVAKTPQATTPPVAASSASSPTTPSSAAALPPTSSAAPADPCAVNLASPAIVRVVSELPRDPRSQQPWNPEPLAGNYNECAQLSAVIVKANTNDTNPTTRAVMFHLGQFIKQGVPDTYGFTGVDESQSTGDTVALTYSGGITGLNSLVKFRWNGSGVEVLGNTPGG
>NZ_CP009483.1|WP_036392490.1|1516894_1517416_+|hypothetical-protein
MVGLACGVIAMIRASKGVRAGKAMAIAGTLLCVLALILATFWIVVIANSFKDRGDSRKAITGQSTEDILRNDLDVQFGQFVTDDNPDRSGKMIVTLRNKSNKSASFSVDVEALDASGNRIAGDTAFVEVLAPGQATRKDMFVFVASDKHDAMKKATFRVVEASKYAPMPPPVK
>NZ_CP009483.1|WP_023366408.1|1514564_1516277_-|cold-shock-protein
MLTPDNMPVAPPDTFVDLQIHPSVLRAIAGVGYESPTAIQAATIPALMAGSDVVGLAQTGTGKTAAFAIPILSKIDVTSTATQALILAPTRELALQVAEAFSRYGAYLPKLNVLPIYGGSSYAVQLAGLRRGAQIIVGTPGRVIDHLERGTLDLSRVDYLVLDEADEMLAMGFAEDVERILSDTPEYKQVALFSATMPPAIRKITTKYLHDPLEVTSKAKTATAENISQRYIQVAGPRKMDALTRVLEVEPFEAMIVFVRTKQATEEVAEKLRARGFSAAAINGDIPQQQRERTITALREGGPNGIDILVATDVAARGLDVERISHVLNYDIPHDTESYVHRIGRTGRAGRPGAALLFVSPRERHLLKAIEKATRQTMTEAELPTVEDVNAQRVAKFSDSITDALAKPGVALFRKLVEDYEREHDVPMADIAAALALQSRDGEAFLLAPEPPPERRSETKKPASDQHAEKRRNGPALSTYRISVGKRHKIGPGAIVGAIANEGGLHRSEFGHISIGPDFSLVELPAKLPRATLKKLESTRISGVLINLRRDGPVKASRYDRGKPRRKRIG
>NZ_CP009483.1|WP_023366406.1|1513428_1514568_-|acyltransferase
MTLSKAEDDQGGLEQISHVDRVASLTGIRAVAALLVVGTHAAYSTGKYTHGYWGLVSSRMEIGVPIFFVLSGYLLFRPWVRSAATDGPPPSLSRYAWHRVRRIMPAYVVVVLIAYVIYHFRTAGPNPGHSWMGLVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEAAFYVALPFLAYVLLVLVSRRRWQPRLMVGALAGMATITPVWLVLIHTVGWFPDGARLWLPSYLAWFLGGMMLTVLQAMGVRCYAFAALPLAVICYFIASTPIAGAPTTSPSAVTEAVVKACFYAVIATLAVAPLALGDQGWYSRLLASRPMVWLGEISYEIFLVHLVTMEFAMVHVVRYRVYTGSMLNLFIATMVVTIPVAWLLHRFTRVKT
>NZ_CP009483.1|WP_023366404.1|1512630_1513347_-|siderophore-interacting-protein
MTEHKASRGWQGAVLKLMRAGDYRLTVTGWREISPHYLRLSFDDGGMLGEHAVHPTMWIRMWFSDGDKSHQRGYTLVDPDPAAGAFDVEFALHEGIASDWARNAQPGDTIDATVLGSKFAIPDPPPGGYVIVGDTASLPAINSLLESIGEAPARVFLEAGYDEDKSLPVARTDDVTWVDRKDDGNALLETVRGAAFDAGDHFGWVASSTRTTRSVAKALREDFGIPRKSIKAQAYWMA
>NZ_CP009483.1|WP_042311916.1|1511839_1512541_+|PPE-family-protein
MSYAMFPPEVNSALLCSGAGSGPMLTAATAWGELAGELRSAAASFASVTSDLACGAWQGAAAAKMTEAAAPYAAWLATAASHSEGAACQAGAVVAAFEAACAATVSPVIIAANRAITRALANTNIFGFNMPAIAAMEAEYEEMWARDVSAMFGYHVGVSQAWSQLFPIQQLLRGLPRIPIPPCPTTPPPTTPPVTPPPPPRPTPPPTPTPRPVPPIHRVPVEPRIPTVPVMRK
>NZ_CP009483.1|WP_023366397.1|1510726_1511308_+|TetR/AcrR-family-transcriptional-regulator
MAGTDWLAARRTEVAADRILDAAAQLYTVRDPASIGMNEIARAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMQQISGVEDPQERLVASIAATLRMVRESPALAAWFAATRPPIGGELAGQSEVIAALAAAFLQSLGSVGGAAVERRARWAVRVIISLLTFPGRDEADERAMIEDFVVPVVAPVSASP
>NZ_CP009483.1|WP_023366424.1|1525421_1526177_+|hypothetical-protein
MSARRTKRSDPDEQPAATGRPKASSRALAQVIERSAHVQAPAAEAYVARLRRAHPAAGPAEIVAKIEKRFVAAVTASGAAIGIVATLPGIGTLAALLAAAGETAVFLEATALLVLALASVYGIPLDHRERRRALVLAVLVGDNSKSAVAELMGSGRTSGGWVSESVASLPLPAVSKFNTRMFKYFAKRFALKRGALMFGKLLPAGIGAVIGAIGNRLVGKKLVRNARSAFGAPPARWPVTLYVLPTVRDAS
>NZ_CP009483.1|WP_023366426.1|1526362_1530052_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit
MANISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPAQSAPADNQQVATAPPPEPVRPAAEPVRPATKPAGAAGAGNGSPAAAPTKAAAPPPAEGDELQVLRGAAAAVVKNMSASLDVPTATSVRAVPAKLLIDNRIVINNQLKRNRGGKISFTHLLGYALVQAVKQFPNMNRHYTEVDGKPNVVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMAGQGAIIGVGAMEYPAEFQGASQERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHQMLLADDFWDEIFRELGIPYLPVRWRSDNPDSIVDKNPRVIELIAAYRNRGHLMADIDPLRLDKTRFRSHPDLDVCSHGLTLWDLDRLFKVDGCFGGSPYMKLRDVLSILRDAYCRHVGVEYTHILEPEQQQWLQQRVEAKHVKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGVYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDSDGEQRFSVVPMMLHGDAAFAGQGVVAETLNLTNLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACEWVARLAVDFRQEFHKDVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISLKEAEDALRDYQGQLERVFNEVRELEKHAVQPSMSVESEQQVPRGLATAVDKALLARIGDAFLAFPDGFTPHPRVQPVLEKRREMAYEGKIDWAFAELLALGSLVAEGKLVRLSGQDTRRGTFSQRHSVIIDRNTGKEFWPLQLLATNKDGTPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIAVPSTPSNYFHLLRRHALDGIMRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDGIGDRSKVRRILLTSGKIYYELAARKAKDNRDDIAIVRIEQLAPLPKRRLNETLDRYPNATEFFWVQEEPANQGAWPRFGLELPELLPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEILDTAFG
>NZ_CP009483.1|WP_023366428.1|1530129_1530963_+|acetoin-dehydrogenase
MEGFAGKVAVVTGAGSGIGRALALELGRSGASLAISDVDSDGLAQTEEMLKAIGAPVKADRLDVTEREAVLAYADAVNEHFGKVNQIYNNAGIGHTGDVEVCEFKDIDRVMDVDFGGVLNGTKAFLPYLIASGDGHVINISSVFGLFSCAGQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNATAAEGLDAAELAKLFDKRAARTSPERAAKVILDAVRKNKARVLVGPDAKVLDLVVRVTGSGYQRLFMPLFGKLIPAPHR
>NZ_CP009483.1|WP_023366430.1|1531069_1531921_-|hypothetical-protein
MRIGRLAPLLLAAVLAVAGCAAGAGKRPAELVVGSRPDTESMLLADIYVAALRSYGFAARGDTAADPMTNLDAGAFAVVPAFTGQVLQSLQPGASARSDKSVYQAMVAALPEGVAAGDYATAAEDKPALVVTPATSTAWGGSELDLLPRHCDGLVVGMLTGAHPPAAVGSCRLPTPREFADYPAMLTALRAGQLTAGWTTTANPANPADLVVLNDGKDALIQAENVVPLYRRNTLTDRQRLAINEVAGVLDTAALVEMRRQVAGGADPQAVAAAWLGEHPLGR
>NZ_CP009483.1|WP_023366432.1|1531917_1533135_-|NADP-dependent-malic-enzyme
MAVSNVEPLAAHSSSASGPQVAIRSDEIFAAHVGGKLSVALKSPLDTQRALSIAYTPGVAQVSRAIAADRTLTARYTWANRLVAVVSDGSAVLGLGDIGPAASLPVMEGKCALFQAYGGLNAIPIVLDTKDPDEIVETLVRLRPTFGAVNLEDISAPRCFEIERRLVEALDCPVMHDDQHGTAIVVLAALMGATKLLGRDMSSLRVAVSGAGAAGVACTNLLLAMGVSDITVLDSRGILHTGRDDMNSVKVEMAQRTNPDGRTGGLVEALDGADVFLGVSAGVVPEELIATMAADGIVFALSNPDPEIHPEVAAKYATVVATGRSDFPNQINNVLAFPGVFRGALDAGARQITEKMMVAAAEAIYSVVSDDLALDRIVPSPLDSRVGDAVAKAVALAVEPSDTAG
>NZ_CP009483.1|WP_023366436.1|1535027_1536017_-|malate-dehydrogenase
MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRSIELRLLEIEPALKALEGVVMELDDCAFPLLAGVEIGADANKIFDGVNLALLVGARPRTKGMERGDLLEANGAIFTAQGKALNEVAAADVRVGVTGNPANTNALIAMSNAPDIPRERFTALTRLDHNRAISQLAKKTGVKVTDIKKMTIWGNHSATQYPDVFHAEIGGKNAAEVVGDQAWIENDFIPTVAKRGAAVIEARGASSAASAASATIDAARDWLLGTPADDWVSMAVLSDGSYGVPEGLISSFPVTTKDGDWTIVSGLEIDEFSRGRIDKSTAELADERSAVTELKLI
>NZ_CP009483.1|WP_023366438.1|1536223_1537324_+|magnesium-and-cobalt-transport-protein-CorA
MFQGFDALPESLRTVARSRPQHVHPTPSSPAQALVDCGVYVDGRRMPGKYAYTDAVREVRERELEGEQAFVWIGLHEPNHHQMQDVADVFGLHPLAVEDAVHAHQRPKLERYDETLVLVLKTVNYVPHDSVVLAREIVETGEIMIFVGDDFVITVRHGEHGGLSDVRNRMDADPQHLRLGPYAVMHAIADYVVDHYLAVTSLIETDIDSIEEVAFAPGSKLDVEPIYLLKREVLELRRCVNPLSAAFQRMQTENKDLISKEVRRYLRDVADHQTEAAEQIASYDDMLNSLIQAALARVGMQQNMDMRKISAWAGIIAVPTMIAGIYGMNFHFMPELDSRWGYPAVISSMVLVCLFLYLSFRNRNWL
>NZ_CP009483.1|WP_023366440.1|1537515_1538688_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MAEIVLEHVSKSYPNGAAAVDDLSLTIADGEFLILVGPSGCGKTTTLNMIAGLEDISSGELRIDGQRVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLTLAKMKKADIAQKVSETAKILDLTDLLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVQMRGEIARLQKRLGTTTVYVTHDQTEAMTLGDRVVVMHGGVAQQIGTPTELYEHPANVFVAGFIGSPTMNFFPATLTSIGLTLPFGEVTLAPEVQQLIAARAKTENIIVGVRPEHLQDAALIDAYQRIKALTFQVGVDLVESLGADKYVYFTTSAPAVHSAQLDELEAQGEMRENQFAARVSAESKAAIGQSLELAFDTTKLAVFDADSGVNLTIPVVG
>NZ_CP009483.1|WP_023366442.1|1538692_1539532_-|carbohydrate-ABC-transporter-permease
MAAEPLSARRTMAWAIIDVLVVVYALLPVLWIFSLSLKPTSTVKDGKLIPASVTLDNYRGVFRGEFFSSALINSIGVGLITTVIAVLLGAMAAYAVARLAFPGKRVLIGATLLITMFPAISLVTPLFNIERAVGLFDTWPGLILPYITFALPLAIYTLSAFFREVPWDLEKAAKMDGATPGQAFRKVIAPLAAPGLVTAAILVFIFAWNDLLLALSLTATKAAITAPVAIANFTGSSQFEEPTGSIAAGAMVITVPIIVFVLVFQRRIVAGLTSGAVKG
>NZ_CP009483.1|WP_080674206.1|1539521_1540373_-|sugar-ABC-transporter-permease
MAFILVAPAALLMLAVTAYPIGYAVWLSLQRNNLATPDETAFIGLENYRTVLTDRYWWTALTVTLAITVVSVTLEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASYSWYYAWTPGTGYLANLLPHGSAPLTQQVPSLGVVVIAEVWKTTPFMSLLLLAGLALVPEDLLKAAQVDGAGAWRRLTKVILPIIKPAVVVALLFRTLDAFRIFDNIYVLTAGENNTESVSILGYDNLFKGFNVGLGSAISVLIFGCVGIIALTFIKLFGAAAPGSDADGR

Crispr_ID: NZ_CP009483_7

• CRISPR_ID: NZ_CP009483_7
• CRISPR_location: 1937364-1937688
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP009483_7

Consensus_repeat	Method
GCCGGCGGTCTGCCGGCGCTGCCGG	CRISPRCasFinder

spacers of NZ_CP009483_7

>7.1|1937389|32|NZ_CP009483|CRISPRCasFinder
GAGTGTCGCCCACCGATGTGGTGGCCCTGGCG
>7.2|1937446|17|NZ_CP009483|CRISPRCasFinder
CCGCTCTGCCCGGGCTG
>7.3|1937488|20|NZ_CP009483|CRISPRCasFinder
GCGTGGATCCAGCGATGCTG
>7.4|1937533|44|NZ_CP009483|CRISPRCasFinder
CAGGTCTACCGGGCGGCCTTCCGGCGGTTGACCCGGCGATGCTG
>7.5|1937602|20|NZ_CP009483|CRISPRCasFinder
CCGGCGGTCTGCCGGCGCTG
>7.6|1937647|17|NZ_CP009483|CRISPRCasFinder
GCGGGCTGCCGGCGCTG

CRISPR arrays and Neighbor proteins around NZ_CP009483_7

CRISPR arrays

The CRISPR arrays of NZ_CP009483_7

>merge|NZ_CP009483|7|1937364-1937688|CRISPRCasFinder
GCCGCCGGACTGCCCGGTCTGCCCGGAGTGTCGCCCACCGATGTGGTGGCCCTGGCGGCCGGTGGCTTGCCACAGCTGGCGTCCGCTCTGCCCGGGCTGCAGGCCGGTCTGCCGGCGCTGCCGGGCGTGGATCCAGCGATGCTGGCCGCGGCGTTGCCGGCGCTGGCGGCAGGTCTACCGGGCGGCCTTCCGGCGGTTGACCCGGCGATGCTGGCCGCGGCACTGCCCGCACTGACCGCCGGCGGTCTGCCGGCGCTGCCGGGTGGGCTGCCGGCGTTGCCGGGCGGGCTGCCGGCGCTGCCGGGCGGTCTGCCGGCGCTGCCGG

>NZ_CP009483|7|7|1937364-1937688|CRISPRCasFinder
GCCGCCGGACTGCCCGGTCTGCCCG	GAGTGTCGCCCACCGATGTGGTGGCCCTGGCG
GCCGGTGGCTTGCCACAGCTGGCGT	CCGCTCTGCCCGGGCTG
CAGGCCGGTCTGCCGGCGCTGCCGG	GCGTGGATCCAGCGATGCTG
GCCGCGGCGTTGCCGGCGCTGGCGG	CAGGTCTACCGGGCGGCCTTCCGGCGGTTGACCCGGCGATGCTG
GCCGCGGCACTGCCCGCACTGACCG	CCGGCGGTCTGCCGGCGCTG
CCGGGTGGGCTGCCGGCGTTGCCGG	GCGGGCTGCCGGCGCTG
CCGGGCGGTCTGCCGGCGCTGCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023367137.1|1941375_1942581_-|arginine-deiminase	unknown	unknown	gnl|CDD|234949
NZ_CP009483.1|WP_023367133.1|1938718_1940275_+|phospholipid-carrier-dependent-glycosyltransferase	unknown	unknown	gnl|CDD|224839
NZ_CP009483.1|WP_023367147.1|1945777_1946524_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|181382
NZ_CP009483.1|WP_080674043.1|1934151_1935069_+|RNA-polymerase-sigma-70-factor	unknown	unknown	gnl|CDD|132002
NZ_CP009483.1|WP_023367131.1|1937836_1938694_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl|CDD|223390
NZ_CP009483.1|WP_023367125.1|1932932_1934132_+|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl|CDD|224172
NZ_CP009483.1|WP_042312028.1|1926673_1927039_+|PAS-sensor-domain-containing-protein	unknown	unknown	gnl|CDD|379177
NZ_CP009483.1|WP_023367143.1|1943947_1944625_-|hypothetical-protein	unknown	unknown	gnl|CDD|376126
NZ_CP009483.1|WP_036393541.1|1928902_1930609_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023367139.1|1942639_1943257_+|alpha-ketoglutarate-dependent-dioxygenase-AlkB	unknown	unknown	gnl|CDD|225687
NZ_CP009483.1|WP_036393827.1|1943266_1943920_-|hypothetical-protein	unknown	unknown	gnl|CDD|376126
NZ_CP009483.1|WP_023367129.1|1935117_1936401_+|aminodeoxychorismate-synthase	unknown	unknown	gnl|CDD|235634
NZ_CP009483.1|WP_036393542.1|1930622_1932488_-|sensor-domain-containing-phosphodiesterase	unknown	unknown	gnl|CDD|236645
NZ_CP009483.1|WP_036393546.1|1944637_1945630_-|acetyltransferase	unknown	unknown	gnl|CDD|237999
NZ_CP009483.1|WP_036393816.1|1924310_1925864_+|methionine--tRNA-ligase	unknown	unknown	gnl|CDD|237012
NZ_CP009483.1|WP_036393531.1|1922099_1923188_-|resuscitation-promoting-factor-RpfB	unknown	unknown	gnl|CDD|226111
NZ_CP009483.1|WP_036393549.1|1946859_1948395_+|phospholipase-C	unknown	unknown	gnl|CDD|226042
NZ_CP009483.1|WP_023367117.1|1927095_1927761_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP009483.1|WP_036393534.1|1923399_1924269_-|YchF/TatD-family-DNA-exonuclease	unknown	unknown	gnl|CDD|272852
NZ_CP009483.1|WP_023367135.1|1940406_1940715_-|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023367137.1|1941375_1942581_-|arginine-deiminase	gnl|CDD|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_CP009483.1|WP_036393546.1|1944637_1945630_-|acetyltransferase	gnl|CDD|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	4.10297e-19
NZ_CP009483.1|WP_023367147.1|1945777_1946524_+|SAM-dependent-methyltransferase	gnl|CDD|181382	PRK08317, PRK08317, hypothetical protein; Provisional.	1.24975e-25
NZ_CP009483.1|WP_023367133.1|1938718_1940275_+|phospholipid-carrier-dependent-glycosyltransferase	gnl|CDD|224839	COG1928, PMT1, Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].	6.02573e-68
NZ_CP009483.1|WP_023367131.1|1937836_1938694_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl|CDD|223390	COG0313, COG0313, Predicted methyltransferases [General function prediction only].	2.98205e-115
NZ_CP009483.1|WP_023367117.1|1927095_1927761_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.12342e-12
NZ_CP009483.1|WP_042312028.1|1926673_1927039_+|PAS-sensor-domain-containing-protein	gnl|CDD|379177	pfam13426, PAS_9, PAS domain.	1.66476e-12
NZ_CP009483.1|WP_023367143.1|1943947_1944625_-|hypothetical-protein	gnl|CDD|376126	pfam18702, DUF5642, Domain of unknown function (DUF5642). This is a domain of unknown function found in actinobacteria.	2.69273e-71
NZ_CP009483.1|WP_023367139.1|1942639_1943257_+|alpha-ketoglutarate-dependent-dioxygenase-AlkB	gnl|CDD|225687	COG3145, AlkB, Alkylated DNA repair protein [DNA replication, recombination, and repair].	9.64266e-45
NZ_CP009483.1|WP_036393827.1|1943266_1943920_-|hypothetical-protein	gnl|CDD|376126	pfam18702, DUF5642, Domain of unknown function (DUF5642). This is a domain of unknown function found in actinobacteria.	2.08689e-74
NZ_CP009483.1|WP_023367129.1|1935117_1936401_+|aminodeoxychorismate-synthase	gnl|CDD|235634	PRK05877, PRK05877, aminodeoxychorismate synthase component I; Provisional.	0
NZ_CP009483.1|WP_036393542.1|1930622_1932488_-|sensor-domain-containing-phosphodiesterase	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	3.47013e-97
NZ_CP009483.1|WP_036393549.1|1946859_1948395_+|phospholipase-C	gnl|CDD|226042	COG3511, PlcC, Phospholipase C [Cell envelope biogenesis, outer membrane].	0
NZ_CP009483.1|WP_036393816.1|1924310_1925864_+|methionine--tRNA-ligase	gnl|CDD|237012	PRK11893, PRK11893, methionyl-tRNA synthetase; Reviewed.	0
NZ_CP009483.1|WP_036393531.1|1922099_1923188_-|resuscitation-promoting-factor-RpfB	gnl|CDD|226111	COG3583, COG3583, Uncharacterized protein conserved in bacteria [Function unknown].	6.06331e-116
NZ_CP009483.1|WP_023367135.1|1940406_1940715_-|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	1.53341e-21
NZ_CP009483.1|WP_023367125.1|1932932_1934132_+|pyridine-nucleotide-disulfide-oxidoreductase	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	4.43074e-68
NZ_CP009483.1|WP_036393534.1|1923399_1924269_-|YchF/TatD-family-DNA-exonuclease	gnl|CDD|272852	TIGR00010, Uncharacterized_deoxyribonuclease_MG009, hydrolase, TatD family. PSI-BLAST, starting with a urease alpha subunit, finds a large superfamily of proteins, including a number of different enzymes that act as hydrolases at C-N bonds other than peptide bonds (EC 3.5.-.-), many uncharacterized proteins, and the members of this family. Several genomes have multiple paralogs related to this family. However, a set of 17 proteins can be found, one each from 17 of the first 20 genomes, such that each member forms a bidirectional best hit across genomes with all other members of the set. This core set (and one other near-perfect member), but not the other paralogs, form the seed for this model. Additionally, members of the seed alignment and all trusted hits, but not all paralogs, have a conserved motif DxHxH near the amino end. The member from E. coli was recently shown to have DNase activity. [Unknown function, Enzymes of unknown specificity].	1.82178e-112
NZ_CP009483.1|WP_080674043.1|1934151_1935069_+|RNA-polymerase-sigma-70-factor	gnl|CDD|132002	TIGR02957, putative_sigma_factor, RNA polymerase sigma-70 factor, TIGR02957 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.	7.83364e-111

Protein sequences

>NZ_CP009483.1|WP_023367129.1|1935117_1936401_+|aminodeoxychorismate-synthase
MRIDRLGDLGGAPQVLRAVARATVRLGLAPPAALTGEWFGALAVIAPSVSVRPVDRGDAFPVREAPGEPVAPVSGAVGGGWVGYLSYPDPGADGRGSRIPEAAGGWTDCVLRRDRDGHWWYESLSDAPMPDWLVSALATTPAPAGRPVPGTCRIDWAAADREAHRGGVLACLAAITAGEVYQACVCTQFTGTVSGSALDFFIDFVDAAGTSPSRAAYVGGPWGAVASLSPELFLRRHGTGVASSPIKGTLPLEAWPSALRASPKEVAENIMIVDLVRNDLGRVAITGTVTVPELLVVRRAPGVWHLVSTVAAQVPADLPMSALLDAAFPPASVTGTPKLRARQLISQWEQHRRGIYCGTVGFASPIAGSELNVAIRTVEFDAAGNAVLGVGGGITADSDPDAEWQECLHKAAPIVGMAVPATATRVG
>NZ_CP009483.1|WP_080674043.1|1934151_1935069_+|RNA-polymerase-sigma-70-factor
MTPPMTQSPGEHAQRFTLLRPMLFTIAYEILGSATESEDVLQDSYVRWAGVDLETVRDTKSYLAQLVTRQALNALRAGARRREEYVGPWLPEPLLLDEQDPAADVVLAESVSMAMLVLLETLSPDERAVFVLREVFGFDYAEIADAVGKSGPAVRQIAHRAREHVQARRKRYGARPVDPQRHAQITAQFLETATSGDVEALMAMLAPDAAWMADSGGKVSAARRPVVGAERVARAITGLMRKAGALLRVEIATCNSAPAVLFYLGEHLEGVITLEIVDDKITNFYVMRNPEKLTALASPREISRG
>NZ_CP009483.1|WP_023367125.1|1932932_1934132_+|pyridine-nucleotide-disulfide-oxidoreductase
MFEPTPLTGPRTHVVVVGGGYAGTVAANHLRLNADIDITVVNSRPVFVERIRLHQLAAGSGTATVEYGTLLGEGIELIVDTVDRIDSADRRLRLASGAQLEYDYLIYAVGSTGATPAVPGAAEFAYSLADLDGATRLRHILMDLPAAAPVVVVGGGLTGIEAASELAEQGRPVTLVCGGPLGPSLSKRGRRSVARQLRRLGVAVLESVAVSQVRWDAVVLSDHTVLTSAVTVWTAGFEVPDLAARSGLRTDALGRLLTDETLTSADDERIVAAGDCAAPSGQPLRMSCQAAGPLGAQAANTVLSRIAGETPAMLSQAFVGQCISLGRSHGTVQLSRSDDTPVNVAVGGRTGAAIKEAICKGTVWSIRHEAAKPGSYFWFKGGKRAAQLPAEQQAAVKSR
>NZ_CP009483.1|WP_036393542.1|1930622_1932488_-|sensor-domain-containing-phosphodiesterase
MPRSLDLVVTSVATQLMEATASTATQVSQRVLAQLVEQFDVDASFLRHHDHEIRASVLVAEWPPRRDVADPDPEGVVHFTSADPVLTQCEHGRKPVVIRPHRNNRFFRRWLGGSIAAASPSVAAAPLVSGQATTGVLGFVKFGARKWRHEEINTLEAVAALFAQLQARIAAEEKLRYLAEHDDLTGLHNRRALLAHLSERLAAGTPGPVAVLYLDLDRLKSINDYLGHNAGDWFIRLFAQRLRGCVGGQSMIARLGGDEFVVIPDQAMSKGAAESFARRLSSMLRERLAIGGHQITRTVSIGLAVGMPGRDDGTDLLRRADEAVLTAKRAGGNQVALATDDMSLKSAFRNDIELHLQGDIDSDALVLHYLPEVDLWTGAVVAAEALVRWRHPIWGLLLPDSFIGVAESTNLAGELGRCVMRSACAEFSRWRKNGVGQSAVLRINVSPVQLITRGFVRSVADTIEEFGIDGGSVCLEITERAVVHDIEATRKTLSELKDVGVQVAIDDFGTGYAVLSHLKSLPVDMLKIDTGFVRDLGTNAGDLAIVRAIIGLAEAFGLQVVAEGVETPAAALTLMQHGCHRAQGFLLSRPVPGNAMEALLSARWMPMPFLADREALTLGAI
>NZ_CP009483.1|WP_036393541.1|1928902_1930609_-|hypothetical-protein
MVRAIRKSSIVAACAVLLPGGALTGCSSHQPDNSPLTAMVSPAIPSTVQEIPNPLRGQYEDLLEPLFPQRDPAQQRYPAWPASYDASLRVSWRQLQPTDPATLPPDAPDERKYDFSVIDDALSRLAERRMRMTLRVYAYNSCCNASYPNNTNIAIPDWERARPGTNTTYPGPANGAAAGVLQVVPNFNDPTYLNDFVQLLAALGRRYDGDERLSVFEFSGYGDFSENHIAYLRDSLNAAGPAPEDSVAALGYYSQFRDQNITKASIQRLVEANVSAFPRTQLVTSAANPEIIRELLADDVTKKLAAPVGMRSDCLGVYAPMPAWADGSAAHYVQTNDPVVAALRKRLSTALVITEWCQLPSGTTRQAYYEKGLRDIMRYHVSMTSSINFPDDDATSPMDPKLYVLWAQANATAGYRYSVEAKPGSQGLSKDGKVATISVVWTNYGSAAATEKWVPGYRLVDFTGQTVRTLPASVNLKSLVPEAPGDRTAQQPIPASASETVRVELADLPAGHYTLRASVDWQQHKPNGAHVVNYPPMQLARDGRDDSGFYPVATLDIPRDVQTATNGA
>NZ_CP009483.1|WP_023367117.1|1927095_1927761_-|TetR/AcrR-family-transcriptional-regulator
MARQVRSEITRRKILDAAVDVFGEAGYAAAGWGTIIDRTGMTKGALYHHFDSKEALASAIIEEGSEALLGAFRNVCGSASPALENMIHGTFAVAHLLSVDKVARAAEQLTAVLAGFNAAAAHFFSAGVGEMAEQARRAIAEGDLRDDVDPELVSESIVGATFGMRLQANALSGPGANGYGVESPAERLGQLWGLLLPGMTVETSLPYFREFLAREAMRSRQ
>NZ_CP009483.1|WP_042312028.1|1926673_1927039_+|PAS-sensor-domain-containing-protein
MIALQQLPALVVLERIPVPVLATGDDGSILFTNTAFAQMVGRDPDEVLSLRFHEIFHQCPDSASSTLSFVHALANMVVELAHKDGSVVRALMSRSAVRRADDNFALAVFQDLTEQLWEEER
>NZ_CP009483.1|WP_036393816.1|1924310_1925864_+|methionine--tRNA-ligase
MQPYYVTTAIAYPNAAPHVGHAYEYIATDAIARFKRLDGFDVRFLTGTDEHGLKVAQAAAAAGVPTAQLARRNSDVFQRMQEALNISFDRFIRTTDPDHYAASQEIWRRMEAAGDLYLDNYSGWYSVRDERFFVESETQLVDGTRIAIETGTPVTWTEEQTYFFRLSAYADKLLAHYHAHPDFIAPEVRRNEVISFVSGGLKDLSVSRTSFNWGVPVPEHPDHVMYVWVDALTNYLTGAGYPDTGSESFRRYWPADLHMIGKDIIRFHAVYWPAFLMSAGIELPRKVFAHGFLHNRGEKMSKSVGNVIDPVALIQAYGVDQVRYFLLREVPFGQDGSYSDEAIVTRINTDLANELGNLAQRSLSMVAKNLGGVVPEPGEFCDADTELLATADGLLDRVRAHFDRQAMHLALEAIWLMLGDANKYFSTQQPWVLRKSESEADQARFRTTLYTTCEVVRIAALLVQPVMPESAAKMLDLLGQPDDRRAFSAVGTRLAPGTQLPPPTGVFPRYQPPSEVE
>NZ_CP009483.1|WP_036393534.1|1923399_1924269_-|YchF/TatD-family-DNA-exonuclease
MRVSTNRPATPQAPPAPEPLAPLIDAHTHLDACGARDARDVAEVVDRAEAVGVRAVVTVADDLESARWVTRATEWDPRVYAAVALHPTRADALTDAARAEITELVAHPRVVAVGETGMDLYWPGRLDGCAQPVVQREAFAWHIDLAKRTGKPLMIHNRQADREVLDVLRAEGAPDTVIFHCFSSGSAMARECVAAGWLLSLSGTVTFRNARDLREAVPLIPLEHVLVETDAPFLTPHPYRGTANEPYCLPYTVRALAELVDRRPEEVAQITTSNAARAYELGHTAGGWP
>NZ_CP009483.1|WP_036393531.1|1922099_1923188_-|resuscitation-promoting-factor-RpfB
MLRLVVGALLLGLAFAGGYAVSAAKTVTLTVDGTAMRVTTMKSRVIEVVQENGFSVDARDDLYPAGDVVVHDSENIVLRRSRPLEISLDGHDVKKVWTTASTVDEALAQLAMTDTAPAAASRGSRVPLAGMALPVVSAKTVEINDGGVVRTVHLAAPNVAGLLDAAGVPLQGSDQVVPGATTPITDGMQIQVTRYRIERVTERLPLLPDALRIEDPEMNMSRKVVEDAGTPGEQDVTFAVAEVNGVVTGKLPIANVVLTPARDAVVRVGTKPGTDVPPVSDGDIWDAIAGCEAGGNWAINTGNGYYGGVQFDQGTWEANGGLRYAPRADLATREEQIAVAEVTRQRQGWGAWPVCSGRAGTR
>NZ_CP009483.1|WP_023367131.1|1937836_1938694_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MSSGRLLLGATPLGQPADASPRLIDALAGADVVAAEDTRRVKTLARALDVEISGRVVSLFDRVEALRVTALVDAMQAGATVLVVSDAGLPVINDPGYRLVAACIDAGITVTCLPGPSAVTTALVVSGLPSDKFCFEGFAPRKGAARRAWLASLADEQRTCVFFESPRRLAACLRDAVEQLGGARPAAVCRELTKVHEEVVRGSLDELADWATGGVLGEITVVLAGAGATPTADLQSLVEEVEHLVAAGIRVKDACSEVAAAHQGVRSRQLYDAVLLARRETDAAP
>NZ_CP009483.1|WP_023367133.1|1938718_1940275_+|phospholipid-carrier-dependent-glycosyltransferase
MTAPPQQTSGLAEERAAPVISPGPLVPIADFGPVDRMRGWIVTAVITLLAAVTRFLNLGSPTDAGTPIFDEKHYAPQAWQVLHNHGVEDNPGFGLVVHPPVGKQMIAIGEALFGYTGFGWRFSGAVLGVILVALVTRIVRRITRSTLVGGIAGVLLICDGVSFVAARTALLDGFLTFFVVAAFGALIVDRDQVRQRMHVALSENRVAETVWGPRLGVRWWRFGAGVLLGLAFATKWSGLYFIAFFGAMSLAFDVAARRQYQVPRPWLGTLRRDLLPTGYALALIPFAVYLASYAGWFASETAIDRHQVGQTIGPDSVLPLPDAVRSLWYYTAKAFHFHATLTNSAGNHHPWESKPWSWPMSLRPVLYAIDQQNVSGCGGQSCVKAEMLVGTPAMWWLAVPVLLYAAWRMFVRRDWRYAVVLVGYCAGWLPWFADIDRQMYFFYAATMAPFLVMAIALILGDVLYQPGQGRERRTLGLIVVSCYVALVVTNFAWLFPILTGLPISQQTWNMEIWLPSWR
>NZ_CP009483.1|WP_023367135.1|1940406_1940715_-|DUF732-domain-containing-protein
MGLLLSAFTTIGIAAPALADAGVDLGARDVGFLGALQDAGITYSNPGHAVESAHAMCRNLHHGESGLQAVQQVKIQNPPIDLDTASRFAVIAAKYYCPEQLY
>NZ_CP009483.1|WP_023367137.1|1941375_1942581_-|arginine-deiminase
MGVELGSNSEVGTLRVAILHRPGTELRRLTPRNSDQLLFDGLPWVSRAQEEHDEFAELLRSRGVTVLLLSELLTEALASGAARMQGVAAAVDARRLGLPLAQQLSAYLRSLDPVRLAHVLTAGMTFNELPSDIRTDVSLVVRMHQGGDFVIEPLPNLVFTRDSSIWIGPRVVIPSLALRARVREASLTDIIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAEALARSLFDDDLAHTVLAVPIAQKRAQMHLDTVCTMVDVDTVVMYAAVVDTLSAFTIRRCPNGATISDAAPFVQAAADAMGIEKLRVIGTGLDPVVAEREQWDDGNNTLALAPGVVVAYERNAQTNARLEAAGIEVLTIAGSELGTGRGGPRCMSCPAARDPL
>NZ_CP009483.1|WP_023367139.1|1942639_1943257_+|alpha-ketoglutarate-dependent-dioxygenase-AlkB
MCDKLAGVAFAVQGSLFEHNERRQLGNGAFIDIRAGWLHGGDDLLAALLAGVPWRSERRQMYDRVVDVPRLVSFHDLTVEDPPHPQLTRIRRRLNDIYGGELGEPFTTVGLCYYRDGSDSVAWHGDTIGRSSTEDTMVAIVSLGATRVFALRPRGGGTSLRFPLAHGDLLVMGGSCQRTWEHAVPKTTAPTGPRVSIQFRPRDVR
>NZ_CP009483.1|WP_036393827.1|1943266_1943920_-|hypothetical-protein
MSKVVLALVAVCLLVGCSPGASQSPKADIAKVIDVKASFGPGFTVNDVPPRAIDPQFFAARKLPDGLSFDPANCAKAALGPQMPSGVQGNMAAVTAEGNGNRFVVIAVETSQQLPFNDPGKECGRIAFSGAQVRGGIEMVAAPHIDGAQTLGVHRVLQALVDGSARTGELYDYSAQFGYYQVNVIANPLVIPNQPVAPVDVQRARDLLVKAVAAIRG
>NZ_CP009483.1|WP_023367143.1|1943947_1944625_-|hypothetical-protein
MRPLWIGVMATALAAACAQSPAPVTAPTHTSPSAHPTTVNPANIKRISRELPPGYEVTRDIPAGASPRLVFGLGANATAQPAPCATLADPGHGRDQSAQGVSGSGEGGIVGAVVVAVRPRPVAPGSDVVAGCAQWTMSDGHTSAAIRLIDPPHIDGAPTLAMVADVRTSVESGTEIDSRTYTFIAYLGDYYAFTTLTTDPGSMLPPLPPRFAADLLVKTVSTLRG
>NZ_CP009483.1|WP_036393546.1|1944637_1945630_-|acetyltransferase
MAELTGARTAELAGMDIFAGCPADDLLPLAARLAPLRAAAGQVLMRQGEQAVSFLLISSGSAEVIHVGDDGAVIVEQALPGMIVGEIALLRDIPRTATVTTVEPLTGWIGGTDALDRMVNIPGIMDRLVRTVRQRLAAFITPVPVRIRDGTQLLLRPVLPGDSERTVHGHIHFSSETIYRRFMSARVPDAAMMHYLSEVDYVDHFVWVMIDGIDPVADARFIRDEHDPTVAEIAFTVADAYQGRGIGSFLIGALSVAARVGGVERFSARMLSDNVPMRTIMDRHGAIWQREDIGVITTVIDVPGPRALDFGREMAEQIRRVARQVIEAVS
>NZ_CP009483.1|WP_023367147.1|1945777_1946524_+|SAM-dependent-methyltransferase
MNTSPDPRESTRGLLNTAAVLRHGFLDVLGESTSSPVPTLAQRAMNSRFVATVYERLWRPTSFYLASGITARAEQRRAAAALRLSTAHRLLDVACGPGNFTAPLARCLPAGALAVGFDISEPMLTRAVVDNDGPQTCYVRGDARVLPFDDETFDAVCCFGALYLMPEPFDITREMLRVLRPGGRIAILTSYAGQAAPIRKALTATANLIGLTMFDRSSFVDLFSSAGLVDIEQQTQRALQFVAATKPR
>NZ_CP009483.1|WP_036393549.1|1946859_1948395_+|phospholipase-C
MSRREFMARIATAGSAGALMSLAGPVIERAYGAGPCSGHLTDIEHFVLMLQENRSFDHFFGTLSGINGFDTPSPSFQQKGWNPQTQSIDPAGVTIPYRFDTTRGPVLNGACVNDPAHQWITIHKSWNNGANDNWLPAQAEQQTLQGNVPVSMGYYTRQDQPIHYLLADTFTICDGYYCSLLGGTSPNRLYWISAWIDPDGVAGGPLLIDPNIQPQAQFSWRTMPDNLSDAGISWKVYQNKLLGALNNTVIGYNGMLVDFKQAQDPRSNIARNGIAPTYPLDFVADVAANRLPQVSWVLPGFQVSEHPGLPVTPAVGGTAIVNILRILLSNPQVWEKTALIVSFDENGGFFDHVTPPTAPPGTPGEYVTVPDIDAVTGSGGIRGPIGLGYRVPCFIISPYSRGPLMVHDTFDHTSQLRLLEKRFGVPVPNLSAWRRSVTGDMTSTFNFAVPPNPAPPNLDHPALQAIPPQVQCVPDTVATFAKVTPPYRVPFPQVMPTQETTPARGIPSGPC

Crispr_ID: NZ_CP009483_9

• CRISPR_ID: NZ_CP009483_9
• CRISPR_location: 2785026-2785197
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas3

Consensus repeat of NZ_CP009483_9

Consensus_repeat	Method
TGTTCGGCAACGGCGGGGCCGGCGG	CRISPRCasFinder

spacers of NZ_CP009483_9

>9.1|2785051|20|NZ_CP009483|CRISPRCasFinder
GGCGGGCGGGGATGGCGGGC
>9.2|2785096|32|NZ_CP009483|CRISPRCasFinder
AGCCGGTGGCGGCACGTTGACCACGGGCAGCA
>9.3|2785153|20|NZ_CP009483|CRISPRCasFinder
GAAAGCCCCGCTGATCGGTA

CRISPR arrays and Neighbor proteins around NZ_CP009483_9

CRISPR arrays

The CRISPR arrays of NZ_CP009483_9

>merge|NZ_CP009483|9|2785026-2785197|CRISPRCasFinder
CGATCGGCATCGGCGGCGACGGCGGGGCGGGCGGGGATGGCGGGCTGATCGGCAATGGCGGCGACGGCGGAGCCGGTGGCGGCACGTTGACCACGGGCAGCACCGGCGGCAACGGTGGTAACGGCGGGAAAGCCCCGCTGATCGGTAGCGGCGGCAACGGCGGCAACGCCGG

>NZ_CP009483|9|9|2785026-2785197|CRISPRCasFinder
CGATCGGCATCGGCGGCGACGGCGG	GGCGGGCGGGGATGGCGGGC
TGATCGGCAATGGCGGCGACGGCGG	AGCCGGTGGCGGCACGTTGACCACGGGCAGCA
CCGGCGGCAACGGTGGTAACGGCGG	GAAAGCCCCGCTGATCGGTA
GCGGCGGCAACGGCGGCAACGCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023368573.1|2777878_2778916_+|hypothetical-protein	unknown	unknown	gnl|CDD|376047
NZ_CP009483.1|WP_052492301.1|2775612_2776191_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368575.1|2780362_2780935_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368576.1|2781058_2781370_-|ESX-1-secretion-associated-protein	unknown	unknown	gnl|CDD|371259
NZ_CP009483.1|WP_080674231.1|2791286_2791625_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368585.1|2788731_2789775_-|hypothetical-protein	unknown	unknown	gnl|CDD|274798
NZ_CP009483.1|WP_007772268.1|2772656_2772860_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP009483.1|WP_023368580.1|2785311_2785668_-|helicase	unknown	unknown	gnl|CDD|274799
NZ_CP009483.1|WP_023368568.1|2768843_2771639_-|type-I-DNA-topoisomerase	unknown	unknown	gnl|CDD|236048
NZ_CP009483.1|WP_023368586.1|2790278_2791136_+|HAD-IB-family-hydrolase	unknown	unknown	gnl|CDD|273654
NZ_CP009483.1|WP_036394444.1|2785962_2786166_-|DUF4244-domain-containing-protein	unknown	unknown	gnl|CDD|379429
NZ_CP009483.1|WP_080674230.1|2785639_2785888_-|pilus-biosynthesis-protein-TadE	unknown	unknown	unknown
NZ_CP009483.1|WP_023368569.1|2771833_2772412_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368587.1|2791621_2792380_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368570.1|2773109_2775434_+|DEAD/DEAH-box-helicase	cas3	mkCas0139_cas3_CAS-I	gnl|CDD|274800
NZ_CP009483.1|WP_042312237.1|2776434_2777754_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NZ_CP009483.1|WP_042312247.1|2787568_2788735_-|hypothetical-protein	unknown	unknown	gnl|CDD|200328
NZ_CP009483.1|WP_023368582.1|2786187_2786778_-|hypothetical-protein	unknown	unknown	gnl|CDD|224975
NZ_CP009483.1|WP_023368577.1|2781442_2782615_-|hypothetical-protein	unknown	unknown	gnl|CDD|237537
NZ_CP009483.1|WP_023368583.1|2786774_2787572_-|membrane-protein	unknown	unknown	gnl|CDD|227300

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP009483.1|WP_023368570.1|2773109_2775434_+|DEAD/DEAH-box-helicase	cas3	mkCas0139_cas3_CAS-I	1.5e-16	54.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023368573.1|2777878_2778916_+|hypothetical-protein	gnl|CDD|376047	pfam18621, DUF5628, Family of unknown function (DUF5628). This is a domain of unknown function found in Actinobacteria.	1.06774e-64
NZ_CP009483.1|WP_023368570.1|2773109_2775434_+|DEAD/DEAH-box-helicase	gnl|CDD|274800	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase. A conserved gene neighborhood widely spread in the Actinobacteria contains this uncharacterized DEAH-box family helicase encoded convergently towards an operon of genes for protein homologous to type II secretion and pilus formation proteins. The context suggests that this helicase may play a role in conjugal transfer of DNA.	0
NZ_CP009483.1|WP_023368585.1|2788731_2789775_-|hypothetical-protein	gnl|CDD|274798	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein. Members of this protein family belong to the MinD/ParA family of P-loop NTPases, and in particular show homology to the CpaE family of pilus assembly proteins (see ). Nearly all members are found, not only in a gene context consistent with pilus biogenesis or a pilus-like secretion apparatus, but also near a DEAD/DEAH-box helicase, suggesting an involvement in DNA transfer activity. The model describes a clade restricted to the Actinobacteria.	3.40357e-87
NZ_CP009483.1|WP_007772268.1|2772656_2772860_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	2.2582e-35
NZ_CP009483.1|WP_023368580.1|2785311_2785668_-|helicase	gnl|CDD|274799	TIGR03816, tadE_like_DECH, helicase/secretion neighborhood TadE-like protein. Members of this small, highly hydrophobic protein family occur in a pilus/secretion-like region that usually is next to an uncharacterized DEAH-box helicase, in Actinobacteria. Members show sequence similarity to the TadE-like family described by pfam07811. The function is unknown. [Unknown function, General].	1.92638e-08
NZ_CP009483.1|WP_023368568.1|2768843_2771639_-|type-I-DNA-topoisomerase	gnl|CDD|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0
NZ_CP009483.1|WP_036394444.1|2785962_2786166_-|DUF4244-domain-containing-protein	gnl|CDD|379429	pfam14029, DUF4244, Protein of unknown function (DUF4244). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 66 and 95 amino acids in length. There is a conserved EYA sequence motif.	4.36329e-16
NZ_CP009483.1|WP_023368582.1|2786187_2786778_-|hypothetical-protein	gnl|CDD|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	4.10416e-11
NZ_CP009483.1|WP_023368576.1|2781058_2781370_-|ESX-1-secretion-associated-protein	gnl|CDD|371259	pfam10824, T7SS_ESX_EspC, Excreted virulence factor EspC, type VII ESX diderm. T7SS_ESX-EspC is a family of exported virulence proteins from largely Acinetobacteria and a few Fimicutes, Gram-positive bacteria. It is exported in conjunction with EspA as an interacting pair.ED F8ADQ6.1/227-313; F8ADQ6.1/227-313;.	7.85434e-19
NZ_CP009483.1|WP_042312237.1|2776434_2777754_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.80968e-35
NZ_CP009483.1|WP_042312247.1|2787568_2788735_-|hypothetical-protein	gnl|CDD|200328	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase. Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.	7.82609e-163
NZ_CP009483.1|WP_023368586.1|2790278_2791136_+|HAD-IB-family-hydrolase	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	2.86106e-83
NZ_CP009483.1|WP_023368577.1|2781442_2782615_-|hypothetical-protein	gnl|CDD|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	0.00630879
NZ_CP009483.1|WP_023368583.1|2786774_2787572_-|membrane-protein	gnl|CDD|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	2.48548e-38

Protein sequences

>NZ_CP009483.1|WP_023368577.1|2781442_2782615_-|hypothetical-protein
MSRAFIIDPTIGFIDGMYVLLGIGVPDDGGIINSALSFFAKALDDLGSAFPGDSWQGSAAENYAGKNKDQLNFFQQLAELDRELQQLIADQANAVEKTRDVLAGVRKGLEFVRPVAVDLTYIPLVGWAMSASFQAPICAAGMAVVGGALAYLTVETLIHTAQLLGLLAKLASLLASVVVDIVSDVVDIIDDILVDVWDFITNPIGFLENLLGDLAQWAYALLSKWGSTLESFFMGVPGLAGMSGGLSQLTGFFSSPTASGSAGLASLDSLAGAGLPGLPGVGAGLGGLPNGLGGLTNVAQLRSAADRQDVRPHDDASAKPLSEQLGAQQQSPAAQGPQGLGGMHPAAGSAKGAPGKKYAEGAAAGTDGEERAPVEAGVGGGQLVSARRVV
>NZ_CP009483.1|WP_023368576.1|2781058_2781370_-|ESX-1-secretion-associated-protein
MTNILKVQPELLDVLASHQHNAAASASSGVAATAGLAESVAISHGSYCKQFNDTLKMYESAHNAFGSSLHAAGIALAKNLRTAARAYLDADETWRQAIESLNF
>NZ_CP009483.1|WP_023368575.1|2780362_2780935_-|hypothetical-protein
MDLCKNDFDDDDFDTVDSGGDPGAYGVAPPTIDPTVCFPSTASPDRRTGVNDAHGRAEDVAPEDIATFIVTNPERTISVSALMDGRIDDIQLSTRVASMSETRLASEILMIADLARQKAQAAQYTFILDRMAQLADGDGQHAAQLRESVSTLWNLPTPEQAAAAEAEAFATHYQRDCPEQSDGDDDWGFA
>NZ_CP009483.1|WP_023368573.1|2777878_2778916_+|hypothetical-protein
MTHDWLLVETLGDEPAVVAQGRQLKNLVPITTFLRRSPHLSAVRTAITESLQTGQSLSSITPKSDRVICTEPVVMSDGRVHGVQVWIGPAGAEPPERPIPGPLKWDLTLGVATDTRESLINSGKNPDVEVTYGRAFAEDLPSRELSPNETRVLAMVVKPEPGQTLCSTWDLTDWQGNPIRLGFTARSALEPGPDGREHLVARAINWRAELKGPLVPVDDLAQKILDGLAQAGVHRALVDLNTWTLLKWLDEPCPFYDWRVNEPDKPRVHPDDQELIAAMTKEFANGATSGVLRLPGNDTDWVPVHVTVNRIELEPETFAGLISLRLPTAAELADAGLPTAVPDST
>NZ_CP009483.1|WP_042312237.1|2776434_2777754_+|PE-family-protein
MSFVIAAPDTVAAAASDLATIGSTIGAATAAAATPTTNLLAAAEDEVSAAIAAFFGAHAQSYQTLSAQAQAFHQQFVRALGMGAASYASAEAANVSPLQQLLNAINAPVQNLTGRPLIGNGANGAPGTGQNGGDAGWLIGNGGAGGSGGMSGSGTGLPGGNGGAGGLLFGTGGAGGAGGYSSTNVDGGTGGMGGGGGLLFGAGGAGGAGGVGAGTGGIGGQGGLLFGNGGAGGTGGLGDTGGTGGVGGTGGLFATGGGGGTGGGGPPGGTGGAGGTALLVGNGGAGGTGGTTPEIANGGNGGGGGNAGRPAGNGGTGGDGGGTIGGVTGANGGNGGNGGMFFGSGGDGGNGSVSATDNGGNGGNGGNAGRVGNGGNGGAGADSEVDGGNGGNGGSAQLIGNGGNGGNGGASVGVGSNGTGGKAGTGGTLIGLDGLNGLP
>NZ_CP009483.1|WP_052492301.1|2775612_2776191_+|hypothetical-protein
MSLVIAAPEALAAAGRGWRVRGIGRRQRRARRDRGSAGIQRRCRRGGGGRNVHGGVGGTGGDALLLGNGGIGGAGGAAPAAGFAGPGGTGGQGGVFFGNGGTGGPGGIVLGADGINPQSDWRSTELVVSQADERRRASYLGIKGISGGWRPTPRRSTSTDLHVPAAEDVPSVARAGSNPSRQCTRATEATRM
>NZ_CP009483.1|WP_023368570.1|2773109_2775434_+|DEAD/DEAH-box-helicase
MPSFGSELLAAALAGTPSGESPLRHVAELPPRPGRPTGWPEWAAANVVRAFVERGITVPWSHQLEAAELAHDGRHVVVSTGTASGKSLAYQLPVLNALATDPRARVLYLSPTKALGHDQLRAAHALTAAVPLDDVAPTAYDGDSPAEVRRFARERSRWLFSNPDMVHLSILRNHARWAVLLRGLRFLVVDECHYYRGVFGSNVAMVLRRLLRLCARYSAEPGCGPTVIFASATTDSPGATAAELIGQPVAEVVDDGSPQGARTVALWEPALRTDLTGENGAPVRRSAGAEAARVMADLIAEGAQTLTFVRSRRAAELTALGARARLDDVAPELSGLVASYRAGYLAEDRTALEHALAEGRLRGLATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGRRGQGALVVLVARDDPLDTYLVHHPAALLGKPVERVVIDPGNPYLLGPQLLCAAVELPLDQAEVRSMDAVAVAQGLVDDGLLRRRGDKYFPAPGVEPHAAVDIRGSIGGQIVIVESDTGRLLGSVDTGRAPTCVHPGAVYLHQGESYVVDSLDFEEGIAFVHAEDPGYATFAREITDITVSGPGERSVFGAVTLGLVPVTVTHQVIGYLRRLLNGEVIDFVELDMPEQVLPTTAVMYTITPDALASNGIDTPRIPGSLHAAEHAAIGLLPLMASCDRGDIGGISSAIGPEGLPSVFVYDGYPGGAGFAERGFRRARTWLGATAAAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVLAELVAEGR
>NZ_CP009483.1|WP_007772268.1|2772656_2772860_-|cold-shock-protein
MPQGTVKWFNAEKGFGFIAPEDGSADVFVHYTEIQGSGFRTLEENQKVEFEIGHSPKGPQATGVRSL
>NZ_CP009483.1|WP_023368569.1|2771833_2772412_-|hypothetical-protein
MSQLSFFAAESVPPAVDDLSGVLAASGQIVIVGTGARLSVVVSELWRAVALAEMMRDAGLVAEIARTDEDTPLVRTAADPTLRPIAAAWTRGAVKTVPPRWLPGPRELRTWTLAAGSPEADRYLLGLDPHAPDTYSPLASALMRVGIAPTLIGTRGARPALRISGRRRLSRLVENVGEPPDSPDALAQWPRV
>NZ_CP009483.1|WP_023368568.1|2768843_2771639_-|type-I-DNA-topoisomerase
MAEPRSKRRDSGNGGGRRLVIVESPTKARKLAGYLGPRYIVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVDADFEPLYIISPEKKSTVSELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAILEAAANPRELDIDLVDAQETRRIMDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFRSASYWDIVATLDASVSDPKAQPPTFAARLTSVAGRRVAIGRDFDSLGALRKGASPSPEVTVLDEATATALAARLHGARLTVASAEEKPYTRRPYPPFMTSTLQQEAGRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVAAAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDSDEFRLYELVWQRTVASQMADARGTTLSLRIAGTAGDQDVVFSASGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDAIELTPDGHATNPPPRYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDAIAAGTERRTNWLNNFYFGGEHGVADSVARSGGLKKLVGINLEGIDAREVNSIKLFDDAIGRPVYVRVGKNGPYLERTVTGDNGEPAPQRANLDDSLTPDELTLEIAEQLFATPQEGRVLGVDPQTGHEIVAKDGRYGPYVTEVLPEPAAESGEPAKKAKKSTAAKPRTGSLLRSMDLQTVTLEDALKLLSLPRVVGVDPDSGEEITAQNGRYGPYLKRGKDSRSLATEDQIFTITLDEALKIYAQPKRLGRQSASAPPLRELGTDPASGNPMVIKDGRFGPYVTDGETNASLRKGDDVATITDQRAAELLADRRARGPVKRTAKKTTRKAPARKAVKRS
>NZ_CP009483.1|WP_023368580.1|2785311_2785668_-|helicase
MRWRLRSRDDGGSATVLAVAMVGVLLWVTGAGAYLGSVAVARHRAQAVADLAALAAAARLPDGGPVACARATAVAQAMGVGDAGCAVRDLDVVVTVEVPVAFAGVARAAARAGPAGSK
>NZ_CP009483.1|WP_080674230.1|2785639_2785888_-|pilus-biosynthesis-protein-TadE
MAGLTAVSMQLRCIDAAREAARLAARGDQRSAVDVARRIAPPAAQIELRRDGEFLVASVVARSKLLPTLDIAANAVAAAEPR
>NZ_CP009483.1|WP_036394444.1|2785962_2786166_-|DUF4244-domain-containing-protein
MVANIFHAISARISLLVTDESGMSTVEYAIGTVAAAAFGAILYSVVTGDSVVSALNHIIGRALSTKA
>NZ_CP009483.1|WP_023368582.1|2786187_2786778_-|hypothetical-protein
MSTAAVLLAAALLAGVGPTVVRARAGMPSRAPRVPSRPAQDRDPLAFSSSLDVLAVCLAAGMAVSAAAAATAPSAPPRLAQLLSRAADLLALGADPSVAWSLPPDWPPGSADAHLDALLRLARRSASSGAALADGVAALAAQSRHDATHTATAAAQRAGVLIAGPLGLCFLPAFVCLGLVPVVAGLAGKVLDSGLM
>NZ_CP009483.1|WP_023368583.1|2786774_2787572_-|membrane-protein
MNGLAVASLTLASALVVAPSSPRRWQVLRPHRRQDPLRARWVLWVGGGALVGAVVVLPLTTVLAVAVVGTTATQRYRRRRCGRRAIREAKSLEAAFDVLVGELRVGIHPVQAFGTAADETDGAVAASMRAVAARARLGADVTGGLRAVARMSALPTHWERLAGYWQLASDHGLAIATLMRAAQSDIVERQRFSASVASGLAGARATANILSGLPLLGVLLGQLIGARPVSFLLNGHAGGWLLVIGVALVCAGLLWSDRITDRVAP
>NZ_CP009483.1|WP_042312247.1|2787568_2788735_-|hypothetical-protein
MTGSLIERVRERLATEAAPLRPNVVAAAIRAESGGMLGDTEVLANIRVLQTELTGAGILEPLLCADATTDVLVTAPDAVWVDDGNGLRRSEIRFTDEAAVRRLAQRLALAAGRRLDDAQPWVDGQLSGIGAAGLTVRLHAVLPPVAVEGTCLSLRVLRPTTQDLPALAAAGAIAPQAADLVAQILAARLAFLVSGGTGAGKTTLLAAMLGAVSGAERIVCVEDAAELAPRHPHLVKLVARCANVEGAGEVTMRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHDGGAGTLHANNPGEVPVRLEALGALGGLDRSALHSQLTAAVQVLLHVTRDQAGRRRLSEIAILRRTDSGLVEAVPAWHAECGMTDGAAELRSLLQSRMAA
>NZ_CP009483.1|WP_023368585.1|2788731_2789775_-|hypothetical-protein
MMTAGELRDELDRIAAAVGVRVVHSGSVTRKTWSAAAAVVLDQAAAERCGRIALPRRAHVSVLTGSEPVTATWTVAIAVGAERVLRMPDQENELIRELADAAASARDEGIRGKVVAVIGGCGGAGASLFAVALAHSAAQALLVDLDPWGGGIDLLVGGESAPGVRWPDLALQGGRLHWSAVSEALPRHRGISMLSGTRRGCELDAAPVEAVVDAGRRGGVTVVCDLPRRVTDASHAALDCADLVVLVCPSDVRACAATAAIVPVLTAINPNLGLVVRGPSPGGLRAAEVADIAGVPLLASMRAQPRLAGQLEHGGLRLRRRSTLAAAARRVLAALGHPQGGLNGRAA
>NZ_CP009483.1|WP_023368586.1|2790278_2791136_+|HAD-IB-family-hydrolase
MTVPDPAAHQQTSPRSAGAPPPQVRTAAFFDLDKTIIAKSSTLAFSKPFFAQGLLNRRAVLKSSYAQFIFLLSGADHDQMDRMRVHMTNMCTGWDVEQVKSIVNETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVAPIARALGATHAMATRMVVVDGKYTGEVAFYCYGEGKVQAIRELASREGYPLEHCYAYSDSITDLPMLEAVGHPSVVNPDRGLRRLAIERGWQVLSFSRPVSLRDRIPAPSGAAIATTAAVGVSALAAGAVSYALLRRFAL
>NZ_CP009483.1|WP_080674231.1|2791286_2791625_-|hypothetical-protein
MAGGTTKANCSQKCEAGGDRRIRIAARQHGSRLPSVHFGAAWVGLGAFATLPAAAPPKGPSLPSALRNYAGPQHFCHYRGYDSAWVPGTVLGARVGRTNLLFRIDLGLTGLP
>NZ_CP009483.1|WP_023368587.1|2791621_2792380_-|hypothetical-protein
MTGDPLAALMELPGVTDASDRARAALGRAHRHRANLRGWPVTAAEAALRAARASAVLDGSPARLDDLAEAGTAGDPVFGGALRVAQALEGGGGQLVVVWQKAPLQALARLHTLAAAGLVDDDMLGRPRADSAIGPRLELLADVMTRPTRASAPVVASVAHGELLTLKPFGHADGVVARAVSRLVTIATGLDPHGLGVPEVSWMRQPARYRDTARRFAEGTPDGVAAWLVLCCRALTAGAQEALSIADALPRR

Crispr_ID: NZ_CP009483_8

• CRISPR_ID: NZ_CP009483_8
• CRISPR_location: 2784576-2784955
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: cas3

Consensus repeat of NZ_CP009483_8

Consensus_repeat	Method
TGTTCGGCAACGGCGGGGCCGGCGG	CRISPRCasFinder

spacers of NZ_CP009483_8

>8.1|2784601|38|NZ_CP009483|CRISPRCasFinder
CCCGGGGACCGGGCAAGACGGCGGGCCCGGCGGCCTCT
>8.2|2784664|20|NZ_CP009483|CRISPRCasFinder
GTCCGGCGCACCCGGCCACA
>8.3|2784709|56|NZ_CP009483|CRISPRCasFinder
CCTGTTCGGCAACGGCGGGGCCGGCGGTGCAGGCGGGGCCGGTGTCGACGGCCCAC
>8.4|2784790|23|NZ_CP009483|CRISPRCasFinder
AGCGGGCGGCGCCGGCGGCTGGC
>8.5|2784838|44|NZ_CP009483|CRISPRCasFinder
AGCAGGCGGAACCGCCCTCCCCGCCGGCGGCCACGCGGGCATAC
>8.6|2784907|23|NZ_CP009483|CRISPRCasFinder
CGACGCCGGCGCCAGCGGCACCT

CRISPR arrays and Neighbor proteins around NZ_CP009483_8

CRISPR arrays

The CRISPR arrays of NZ_CP009483_8

>merge|NZ_CP009483|8|2784576-2784955|CRISPRCasFinder
TTATCGGCAACGGGGCCAACGGCGCCCCGGGGACCGGGCAAGACGGCGGGCCCGGCGGCCTCTTGTTCGGCAACGGCGGGGCCGGCGGGTCCGGCGCACCCGGCCACAACGGCGGCAACGGCGGGGCAGCCGGCCTGTTCGGCAACGGCGGGGCCGGCGGTGCAGGCGGGGCCGGTGTCGACGGCCCACCGGGCGGGCCCGGGGGTGCCGGCGGAGCGGGCGGCGCCGGCGGCTGGCTGTACGGTTCCGGCGGTGCCGGCGGAGCAGGCGGAACCGCCCTCCCCGCCGGCGGCCACGCGGGCATACTTCAGGGCGACGGCGGCGCCGGCGGCGACGCCGGCGCCAGCGGCACCTACGGCGGCGCCGGCGGAGCCGGCGGC

>NZ_CP009483|8|8|2784576-2784955|CRISPRCasFinder
TTATCGGCAACGGGGCCAACGGCGC	CCCGGGGACCGGGCAAGACGGCGGGCCCGGCGGCCTCT
TGTTCGGCAACGGCGGGGCCGGCGG	GTCCGGCGCACCCGGCCACA
ACGGCGGCAACGGCGGGGCAGCCGG	CCTGTTCGGCAACGGCGGGGCCGGCGGTGCAGGCGGGGCCGGTGTCGACGGCCCAC
CGGGCGGGCCCGGGGGTGCCGGCGG	AGCGGGCGGCGCCGGCGGCTGGC
TGTACGGTTCCGGCGGTGCCGGCGG	AGCAGGCGGAACCGCCCTCCCCGCCGGCGGCCACGCGGGCATAC
TTCAGGGCGACGGCGGCGCCGGCGG	CGACGCCGGCGCCAGCGGCACCT
ACGGCGGCGCCGGCGGAGCCGGCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023368573.1|2777878_2778916_+|hypothetical-protein	unknown	unknown	gnl|CDD|376047
NZ_CP009483.1|WP_052492301.1|2775612_2776191_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368575.1|2780362_2780935_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368576.1|2781058_2781370_-|ESX-1-secretion-associated-protein	unknown	unknown	gnl|CDD|371259
NZ_CP009483.1|WP_080674231.1|2791286_2791625_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368585.1|2788731_2789775_-|hypothetical-protein	unknown	unknown	gnl|CDD|274798
NZ_CP009483.1|WP_007772268.1|2772656_2772860_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP009483.1|WP_023368580.1|2785311_2785668_-|helicase	unknown	unknown	gnl|CDD|274799
NZ_CP009483.1|WP_023368568.1|2768843_2771639_-|type-I-DNA-topoisomerase	unknown	unknown	gnl|CDD|236048
NZ_CP009483.1|WP_023368586.1|2790278_2791136_+|HAD-IB-family-hydrolase	unknown	unknown	gnl|CDD|273654
NZ_CP009483.1|WP_036394444.1|2785962_2786166_-|DUF4244-domain-containing-protein	unknown	unknown	gnl|CDD|379429
NZ_CP009483.1|WP_080674230.1|2785639_2785888_-|pilus-biosynthesis-protein-TadE	unknown	unknown	unknown
NZ_CP009483.1|WP_023368569.1|2771833_2772412_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368587.1|2791621_2792380_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023368570.1|2773109_2775434_+|DEAD/DEAH-box-helicase	cas3	mkCas0139_cas3_CAS-I	gnl|CDD|274800
NZ_CP009483.1|WP_042312237.1|2776434_2777754_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NZ_CP009483.1|WP_042312247.1|2787568_2788735_-|hypothetical-protein	unknown	unknown	gnl|CDD|200328
NZ_CP009483.1|WP_023368582.1|2786187_2786778_-|hypothetical-protein	unknown	unknown	gnl|CDD|224975
NZ_CP009483.1|WP_023368577.1|2781442_2782615_-|hypothetical-protein	unknown	unknown	gnl|CDD|237537
NZ_CP009483.1|WP_023368583.1|2786774_2787572_-|membrane-protein	unknown	unknown	gnl|CDD|227300

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP009483.1|WP_023368570.1|2773109_2775434_+|DEAD/DEAH-box-helicase	cas3	mkCas0139_cas3_CAS-I	1.5e-16	54.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023368573.1|2777878_2778916_+|hypothetical-protein	gnl|CDD|376047	pfam18621, DUF5628, Family of unknown function (DUF5628). This is a domain of unknown function found in Actinobacteria.	1.06774e-64
NZ_CP009483.1|WP_023368570.1|2773109_2775434_+|DEAD/DEAH-box-helicase	gnl|CDD|274800	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase. A conserved gene neighborhood widely spread in the Actinobacteria contains this uncharacterized DEAH-box family helicase encoded convergently towards an operon of genes for protein homologous to type II secretion and pilus formation proteins. The context suggests that this helicase may play a role in conjugal transfer of DNA.	0
NZ_CP009483.1|WP_023368585.1|2788731_2789775_-|hypothetical-protein	gnl|CDD|274798	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein. Members of this protein family belong to the MinD/ParA family of P-loop NTPases, and in particular show homology to the CpaE family of pilus assembly proteins (see ). Nearly all members are found, not only in a gene context consistent with pilus biogenesis or a pilus-like secretion apparatus, but also near a DEAD/DEAH-box helicase, suggesting an involvement in DNA transfer activity. The model describes a clade restricted to the Actinobacteria.	3.40357e-87
NZ_CP009483.1|WP_007772268.1|2772656_2772860_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	2.2582e-35
NZ_CP009483.1|WP_023368580.1|2785311_2785668_-|helicase	gnl|CDD|274799	TIGR03816, tadE_like_DECH, helicase/secretion neighborhood TadE-like protein. Members of this small, highly hydrophobic protein family occur in a pilus/secretion-like region that usually is next to an uncharacterized DEAH-box helicase, in Actinobacteria. Members show sequence similarity to the TadE-like family described by pfam07811. The function is unknown. [Unknown function, General].	1.92638e-08
NZ_CP009483.1|WP_023368568.1|2768843_2771639_-|type-I-DNA-topoisomerase	gnl|CDD|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0
NZ_CP009483.1|WP_036394444.1|2785962_2786166_-|DUF4244-domain-containing-protein	gnl|CDD|379429	pfam14029, DUF4244, Protein of unknown function (DUF4244). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 66 and 95 amino acids in length. There is a conserved EYA sequence motif.	4.36329e-16
NZ_CP009483.1|WP_023368582.1|2786187_2786778_-|hypothetical-protein	gnl|CDD|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	4.10416e-11
NZ_CP009483.1|WP_023368576.1|2781058_2781370_-|ESX-1-secretion-associated-protein	gnl|CDD|371259	pfam10824, T7SS_ESX_EspC, Excreted virulence factor EspC, type VII ESX diderm. T7SS_ESX-EspC is a family of exported virulence proteins from largely Acinetobacteria and a few Fimicutes, Gram-positive bacteria. It is exported in conjunction with EspA as an interacting pair.ED F8ADQ6.1/227-313; F8ADQ6.1/227-313;.	7.85434e-19
NZ_CP009483.1|WP_042312237.1|2776434_2777754_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.80968e-35
NZ_CP009483.1|WP_042312247.1|2787568_2788735_-|hypothetical-protein	gnl|CDD|200328	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase. Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.	7.82609e-163
NZ_CP009483.1|WP_023368586.1|2790278_2791136_+|HAD-IB-family-hydrolase	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	2.86106e-83
NZ_CP009483.1|WP_023368577.1|2781442_2782615_-|hypothetical-protein	gnl|CDD|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	0.00630879
NZ_CP009483.1|WP_023368583.1|2786774_2787572_-|membrane-protein	gnl|CDD|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	2.48548e-38

Protein sequences

>NZ_CP009483.1|WP_023368577.1|2781442_2782615_-|hypothetical-protein
MSRAFIIDPTIGFIDGMYVLLGIGVPDDGGIINSALSFFAKALDDLGSAFPGDSWQGSAAENYAGKNKDQLNFFQQLAELDRELQQLIADQANAVEKTRDVLAGVRKGLEFVRPVAVDLTYIPLVGWAMSASFQAPICAAGMAVVGGALAYLTVETLIHTAQLLGLLAKLASLLASVVVDIVSDVVDIIDDILVDVWDFITNPIGFLENLLGDLAQWAYALLSKWGSTLESFFMGVPGLAGMSGGLSQLTGFFSSPTASGSAGLASLDSLAGAGLPGLPGVGAGLGGLPNGLGGLTNVAQLRSAADRQDVRPHDDASAKPLSEQLGAQQQSPAAQGPQGLGGMHPAAGSAKGAPGKKYAEGAAAGTDGEERAPVEAGVGGGQLVSARRVV
>NZ_CP009483.1|WP_023368576.1|2781058_2781370_-|ESX-1-secretion-associated-protein
MTNILKVQPELLDVLASHQHNAAASASSGVAATAGLAESVAISHGSYCKQFNDTLKMYESAHNAFGSSLHAAGIALAKNLRTAARAYLDADETWRQAIESLNF
>NZ_CP009483.1|WP_023368575.1|2780362_2780935_-|hypothetical-protein
MDLCKNDFDDDDFDTVDSGGDPGAYGVAPPTIDPTVCFPSTASPDRRTGVNDAHGRAEDVAPEDIATFIVTNPERTISVSALMDGRIDDIQLSTRVASMSETRLASEILMIADLARQKAQAAQYTFILDRMAQLADGDGQHAAQLRESVSTLWNLPTPEQAAAAEAEAFATHYQRDCPEQSDGDDDWGFA
>NZ_CP009483.1|WP_023368573.1|2777878_2778916_+|hypothetical-protein
MTHDWLLVETLGDEPAVVAQGRQLKNLVPITTFLRRSPHLSAVRTAITESLQTGQSLSSITPKSDRVICTEPVVMSDGRVHGVQVWIGPAGAEPPERPIPGPLKWDLTLGVATDTRESLINSGKNPDVEVTYGRAFAEDLPSRELSPNETRVLAMVVKPEPGQTLCSTWDLTDWQGNPIRLGFTARSALEPGPDGREHLVARAINWRAELKGPLVPVDDLAQKILDGLAQAGVHRALVDLNTWTLLKWLDEPCPFYDWRVNEPDKPRVHPDDQELIAAMTKEFANGATSGVLRLPGNDTDWVPVHVTVNRIELEPETFAGLISLRLPTAAELADAGLPTAVPDST
>NZ_CP009483.1|WP_042312237.1|2776434_2777754_+|PE-family-protein
MSFVIAAPDTVAAAASDLATIGSTIGAATAAAATPTTNLLAAAEDEVSAAIAAFFGAHAQSYQTLSAQAQAFHQQFVRALGMGAASYASAEAANVSPLQQLLNAINAPVQNLTGRPLIGNGANGAPGTGQNGGDAGWLIGNGGAGGSGGMSGSGTGLPGGNGGAGGLLFGTGGAGGAGGYSSTNVDGGTGGMGGGGGLLFGAGGAGGAGGVGAGTGGIGGQGGLLFGNGGAGGTGGLGDTGGTGGVGGTGGLFATGGGGGTGGGGPPGGTGGAGGTALLVGNGGAGGTGGTTPEIANGGNGGGGGNAGRPAGNGGTGGDGGGTIGGVTGANGGNGGNGGMFFGSGGDGGNGSVSATDNGGNGGNGGNAGRVGNGGNGGAGADSEVDGGNGGNGGSAQLIGNGGNGGNGGASVGVGSNGTGGKAGTGGTLIGLDGLNGLP
>NZ_CP009483.1|WP_052492301.1|2775612_2776191_+|hypothetical-protein
MSLVIAAPEALAAAGRGWRVRGIGRRQRRARRDRGSAGIQRRCRRGGGGRNVHGGVGGTGGDALLLGNGGIGGAGGAAPAAGFAGPGGTGGQGGVFFGNGGTGGPGGIVLGADGINPQSDWRSTELVVSQADERRRASYLGIKGISGGWRPTPRRSTSTDLHVPAAEDVPSVARAGSNPSRQCTRATEATRM
>NZ_CP009483.1|WP_023368570.1|2773109_2775434_+|DEAD/DEAH-box-helicase
MPSFGSELLAAALAGTPSGESPLRHVAELPPRPGRPTGWPEWAAANVVRAFVERGITVPWSHQLEAAELAHDGRHVVVSTGTASGKSLAYQLPVLNALATDPRARVLYLSPTKALGHDQLRAAHALTAAVPLDDVAPTAYDGDSPAEVRRFARERSRWLFSNPDMVHLSILRNHARWAVLLRGLRFLVVDECHYYRGVFGSNVAMVLRRLLRLCARYSAEPGCGPTVIFASATTDSPGATAAELIGQPVAEVVDDGSPQGARTVALWEPALRTDLTGENGAPVRRSAGAEAARVMADLIAEGAQTLTFVRSRRAAELTALGARARLDDVAPELSGLVASYRAGYLAEDRTALEHALAEGRLRGLATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGRRGQGALVVLVARDDPLDTYLVHHPAALLGKPVERVVIDPGNPYLLGPQLLCAAVELPLDQAEVRSMDAVAVAQGLVDDGLLRRRGDKYFPAPGVEPHAAVDIRGSIGGQIVIVESDTGRLLGSVDTGRAPTCVHPGAVYLHQGESYVVDSLDFEEGIAFVHAEDPGYATFAREITDITVSGPGERSVFGAVTLGLVPVTVTHQVIGYLRRLLNGEVIDFVELDMPEQVLPTTAVMYTITPDALASNGIDTPRIPGSLHAAEHAAIGLLPLMASCDRGDIGGISSAIGPEGLPSVFVYDGYPGGAGFAERGFRRARTWLGATAAAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVLAELVAEGR
>NZ_CP009483.1|WP_007772268.1|2772656_2772860_-|cold-shock-protein
MPQGTVKWFNAEKGFGFIAPEDGSADVFVHYTEIQGSGFRTLEENQKVEFEIGHSPKGPQATGVRSL
>NZ_CP009483.1|WP_023368569.1|2771833_2772412_-|hypothetical-protein
MSQLSFFAAESVPPAVDDLSGVLAASGQIVIVGTGARLSVVVSELWRAVALAEMMRDAGLVAEIARTDEDTPLVRTAADPTLRPIAAAWTRGAVKTVPPRWLPGPRELRTWTLAAGSPEADRYLLGLDPHAPDTYSPLASALMRVGIAPTLIGTRGARPALRISGRRRLSRLVENVGEPPDSPDALAQWPRV
>NZ_CP009483.1|WP_023368568.1|2768843_2771639_-|type-I-DNA-topoisomerase
MAEPRSKRRDSGNGGGRRLVIVESPTKARKLAGYLGPRYIVESSRGHIRDLPRAAADVPAKYKSEPWARLGVNVDADFEPLYIISPEKKSTVSELKGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAILEAAANPRELDIDLVDAQETRRIMDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVQRERDRMAFRSASYWDIVATLDASVSDPKAQPPTFAARLTSVAGRRVAIGRDFDSLGALRKGASPSPEVTVLDEATATALAARLHGARLTVASAEEKPYTRRPYPPFMTSTLQQEAGRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGEEYVAAAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDSDEFRLYELVWQRTVASQMADARGTTLSLRIAGTAGDQDVVFSASGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDAIELTPDGHATNPPPRYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDAIAAGTERRTNWLNNFYFGGEHGVADSVARSGGLKKLVGINLEGIDAREVNSIKLFDDAIGRPVYVRVGKNGPYLERTVTGDNGEPAPQRANLDDSLTPDELTLEIAEQLFATPQEGRVLGVDPQTGHEIVAKDGRYGPYVTEVLPEPAAESGEPAKKAKKSTAAKPRTGSLLRSMDLQTVTLEDALKLLSLPRVVGVDPDSGEEITAQNGRYGPYLKRGKDSRSLATEDQIFTITLDEALKIYAQPKRLGRQSASAPPLRELGTDPASGNPMVIKDGRFGPYVTDGETNASLRKGDDVATITDQRAAELLADRRARGPVKRTAKKTTRKAPARKAVKRS
>NZ_CP009483.1|WP_023368580.1|2785311_2785668_-|helicase
MRWRLRSRDDGGSATVLAVAMVGVLLWVTGAGAYLGSVAVARHRAQAVADLAALAAAARLPDGGPVACARATAVAQAMGVGDAGCAVRDLDVVVTVEVPVAFAGVARAAARAGPAGSK
>NZ_CP009483.1|WP_080674230.1|2785639_2785888_-|pilus-biosynthesis-protein-TadE
MAGLTAVSMQLRCIDAAREAARLAARGDQRSAVDVARRIAPPAAQIELRRDGEFLVASVVARSKLLPTLDIAANAVAAAEPR
>NZ_CP009483.1|WP_036394444.1|2785962_2786166_-|DUF4244-domain-containing-protein
MVANIFHAISARISLLVTDESGMSTVEYAIGTVAAAAFGAILYSVVTGDSVVSALNHIIGRALSTKA
>NZ_CP009483.1|WP_023368582.1|2786187_2786778_-|hypothetical-protein
MSTAAVLLAAALLAGVGPTVVRARAGMPSRAPRVPSRPAQDRDPLAFSSSLDVLAVCLAAGMAVSAAAAATAPSAPPRLAQLLSRAADLLALGADPSVAWSLPPDWPPGSADAHLDALLRLARRSASSGAALADGVAALAAQSRHDATHTATAAAQRAGVLIAGPLGLCFLPAFVCLGLVPVVAGLAGKVLDSGLM
>NZ_CP009483.1|WP_023368583.1|2786774_2787572_-|membrane-protein
MNGLAVASLTLASALVVAPSSPRRWQVLRPHRRQDPLRARWVLWVGGGALVGAVVVLPLTTVLAVAVVGTTATQRYRRRRCGRRAIREAKSLEAAFDVLVGELRVGIHPVQAFGTAADETDGAVAASMRAVAARARLGADVTGGLRAVARMSALPTHWERLAGYWQLASDHGLAIATLMRAAQSDIVERQRFSASVASGLAGARATANILSGLPLLGVLLGQLIGARPVSFLLNGHAGGWLLVIGVALVCAGLLWSDRITDRVAP
>NZ_CP009483.1|WP_042312247.1|2787568_2788735_-|hypothetical-protein
MTGSLIERVRERLATEAAPLRPNVVAAAIRAESGGMLGDTEVLANIRVLQTELTGAGILEPLLCADATTDVLVTAPDAVWVDDGNGLRRSEIRFTDEAAVRRLAQRLALAAGRRLDDAQPWVDGQLSGIGAAGLTVRLHAVLPPVAVEGTCLSLRVLRPTTQDLPALAAAGAIAPQAADLVAQILAARLAFLVSGGTGAGKTTLLAAMLGAVSGAERIVCVEDAAELAPRHPHLVKLVARCANVEGAGEVTMRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHDGGAGTLHANNPGEVPVRLEALGALGGLDRSALHSQLTAAVQVLLHVTRDQAGRRRLSEIAILRRTDSGLVEAVPAWHAECGMTDGAAELRSLLQSRMAA
>NZ_CP009483.1|WP_023368585.1|2788731_2789775_-|hypothetical-protein
MMTAGELRDELDRIAAAVGVRVVHSGSVTRKTWSAAAAVVLDQAAAERCGRIALPRRAHVSVLTGSEPVTATWTVAIAVGAERVLRMPDQENELIRELADAAASARDEGIRGKVVAVIGGCGGAGASLFAVALAHSAAQALLVDLDPWGGGIDLLVGGESAPGVRWPDLALQGGRLHWSAVSEALPRHRGISMLSGTRRGCELDAAPVEAVVDAGRRGGVTVVCDLPRRVTDASHAALDCADLVVLVCPSDVRACAATAAIVPVLTAINPNLGLVVRGPSPGGLRAAEVADIAGVPLLASMRAQPRLAGQLEHGGLRLRRRSTLAAAARRVLAALGHPQGGLNGRAA
>NZ_CP009483.1|WP_023368586.1|2790278_2791136_+|HAD-IB-family-hydrolase
MTVPDPAAHQQTSPRSAGAPPPQVRTAAFFDLDKTIIAKSSTLAFSKPFFAQGLLNRRAVLKSSYAQFIFLLSGADHDQMDRMRVHMTNMCTGWDVEQVKSIVNETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVAPIARALGATHAMATRMVVVDGKYTGEVAFYCYGEGKVQAIRELASREGYPLEHCYAYSDSITDLPMLEAVGHPSVVNPDRGLRRLAIERGWQVLSFSRPVSLRDRIPAPSGAAIATTAAVGVSALAAGAVSYALLRRFAL
>NZ_CP009483.1|WP_080674231.1|2791286_2791625_-|hypothetical-protein
MAGGTTKANCSQKCEAGGDRRIRIAARQHGSRLPSVHFGAAWVGLGAFATLPAAAPPKGPSLPSALRNYAGPQHFCHYRGYDSAWVPGTVLGARVGRTNLLFRIDLGLTGLP
>NZ_CP009483.1|WP_023368587.1|2791621_2792380_-|hypothetical-protein
MTGDPLAALMELPGVTDASDRARAALGRAHRHRANLRGWPVTAAEAALRAARASAVLDGSPARLDDLAEAGTAGDPVFGGALRVAQALEGGGGQLVVVWQKAPLQALARLHTLAAAGLVDDDMLGRPRADSAIGPRLELLADVMTRPTRASAPVVASVAHGELLTLKPFGHADGVVARAVSRLVTIATGLDPHGLGVPEVSWMRQPARYRDTARRFAEGTPDGVAAWLVLCCRALTAGAQEALSIADALPRR

Crispr_ID: NZ_CP009483_10

• CRISPR_ID: NZ_CP009483_10
• CRISPR_location: 3268013-3268117
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_10

Consensus_repeat	Method
GCCCGGGCGCCTGACCGGTCGCCCCGGGA	CRISPRCasFinder

spacers of NZ_CP009483_10

>10.1|3268042|47|NZ_CP009483|CRISPRCasFinder
CGCCGGGGTGGGAGCTTGGGGAGCGGGCGCGGTCGCTGCTCCCCTGT

CRISPR arrays and Neighbor proteins around NZ_CP009483_10

CRISPR arrays

The CRISPR arrays of NZ_CP009483_10

>merge|NZ_CP009483|10|3268013-3268117|CRISPRCasFinder
GCCCGGGCGCCTGACCGGTCGCCCCGGGACGCCGGGGTGGGAGCTTGGGGAGCGGGCGCGGTCGCTGCTCCCCTGTGCCCGGGCGCCTGACCGGTCGCCCCGGGA

>NZ_CP009483|10|10|3268013-3268117|CRISPRCasFinder
GCCCGGGCGCCTGACCGGTCGCCCCGGGA	CGCCGGGGTGGGAGCTTGGGGAGCGGGCGCGGTCGCTGCTCCCCTGT
GCCCGGGCGCCTGACCGGTCGCCCCGGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023369120.1|3272145_3272811_-|short-chain-dehydrogenase	unknown	unknown	gnl|CDD|181298
NZ_CP009483.1|WP_036394844.1|3262621_3263854_+|hypothetical-protein	unknown	unknown	gnl|CDD|376071
NZ_CP009483.1|WP_080674240.1|3264393_3265278_-|TIGR03084-family-protein	unknown	unknown	gnl|CDD|274423
NZ_CP009483.1|WP_023369128.1|3276011_3276773_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP009483.1|WP_036394963.1|3269127_3272055_+|leucine--tRNA-ligase	unknown	unknown	gnl|CDD|234743
NZ_CP009483.1|WP_023369132.1|3277718_3278633_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP009483.1|WP_023369112.1|3266717_3267326_+|DUF179-domain-containing-protein	unknown	unknown	gnl|CDD|234694
NZ_CP009483.1|WP_023369114.1|3267404_3267755_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023369093.1|3260025_3260388_+|DUF4226-domain-containing-protein	unknown	unknown	gnl|CDD|371237
NZ_CP009483.1|WP_023369122.1|3272852_3273353_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP009483.1|WP_023369136.1|3280582_3281692_-|inositol-3-phosphate-synthase	unknown	unknown	gnl|CDD|132491
NZ_CP009483.1|WP_023369110.1|3265289_3266609_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP009483.1|WP_023369095.1|3260450_3261722_+|DUF4226-domain-containing-protein	unknown	unknown	gnl|CDD|371237
NZ_CP009483.1|WP_036394952.1|3263914_3264232_+|DUF2710-domain-containing-protein	unknown	unknown	gnl|CDD|287837
NZ_CP009483.1|WP_023369134.1|3278779_3280399_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_036394846.1|3274159_3275971_-|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP009483.1|WP_023369130.1|3276893_3277682_-|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|213873
NZ_CP009483.1|WP_023369097.1|3261762_3262080_+|ESX-1-secretion-associated-protein	unknown	unknown	gnl|CDD|371259
NZ_CP009483.1|WP_023369124.1|3273416_3274163_-|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224051
NZ_CP009483.1|WP_023369099.1|3262087_3262393_+|DUF2694-domain-containing-protein	unknown	unknown	gnl|CDD|287827

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023369099.1|3262087_3262393_+|DUF2694-domain-containing-protein	gnl|CDD|287827	pfam10904, DUF2694, Protein of unknown function (DUF2694). This family of proteins with unknown function appears to be restricted to Mycobacterium spp.	3.69608e-50
NZ_CP009483.1|WP_036394844.1|3262621_3263854_+|hypothetical-protein	gnl|CDD|376071	pfam18645, DUF5631, Family of unknown function (DUF5631). This is an alpha helical domain found at the C-terminal region of the hypothetical protein Rv3899c from Mycobacterium tuberculosis which is conserved across mycobacteria.	8.14447e-49
NZ_CP009483.1|WP_080674240.1|3264393_3265278_-|TIGR03084-family-protein	gnl|CDD|274423	TIGR03084, conserved_hypothetical_protein, TIGR03084 family protein. This family, like pfam07398, belongs to the larger set of probable enzymes modeled by TIGRFAMs family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized. [Hypothetical proteins, Conserved].	2.10622e-119
NZ_CP009483.1|WP_023369128.1|3276011_3276773_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	6.55555e-30
NZ_CP009483.1|WP_036394963.1|3269127_3272055_+|leucine--tRNA-ligase	gnl|CDD|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP009483.1|WP_023369132.1|3277718_3278633_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.24604e-21
NZ_CP009483.1|WP_023369112.1|3266717_3267326_+|DUF179-domain-containing-protein	gnl|CDD|234694	PRK00228, PRK00228, YqgE/AlgH family protein.	1.50881e-79
NZ_CP009483.1|WP_023369093.1|3260025_3260388_+|DUF4226-domain-containing-protein	gnl|CDD|371237	pfam10774, DUF4226, Domain of unknown function (DUF4226). This family of mycobacterial proteins are uncharacterized.	7.70906e-25
NZ_CP009483.1|WP_023369122.1|3272852_3273353_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.13714e-18
NZ_CP009483.1|WP_023369136.1|3280582_3281692_-|inositol-3-phosphate-synthase	gnl|CDD|132491	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type. This enzyme, inositol 1-phosphate synthase as found in Actinobacteria, produces an essential precursor for several different products, including mycothiol, which is a glutathione analog, and phosphatidylinositol, which is a phospholipid.	0
NZ_CP009483.1|WP_023369110.1|3265289_3266609_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.73151e-30
NZ_CP009483.1|WP_023369095.1|3260450_3261722_+|DUF4226-domain-containing-protein	gnl|CDD|371237	pfam10774, DUF4226, Domain of unknown function (DUF4226). This family of mycobacterial proteins are uncharacterized.	1.78004e-35
NZ_CP009483.1|WP_036394952.1|3263914_3264232_+|DUF2710-domain-containing-protein	gnl|CDD|287837	pfam10921, DUF2710, Protein of unknown function (DUF2710). This family of proteins with unknown function appears to be restricted to Mycobacteriaceae.	4.50432e-46
NZ_CP009483.1|WP_023369134.1|3278779_3280399_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	4.18143e-74
NZ_CP009483.1|WP_036394846.1|3274159_3275971_-|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	6.1636e-66
NZ_CP009483.1|WP_023369130.1|3276893_3277682_-|LLM-class-F420-dependent-oxidoreductase	gnl|CDD|213873	TIGR03856, F420_MSMEG_2906, probable F420-dependent oxidoreductase, MSMEG_2906 family. This model describes a small family of enzymes in the bacterial luciferase-like monooxygenase family, which includes F420-dependent enzymes such as N5,N10-methylenetetrahydromethanopterin reductase as well as FMN-dependent enzymes. All members of this family are from species that produce coenzyme F420; SIMBAL analysis suggests that members of this family bind F420 rather than FMN. [Unknown function, Enzymes of unknown specificity].	4.29588e-175
NZ_CP009483.1|WP_023369097.1|3261762_3262080_+|ESX-1-secretion-associated-protein	gnl|CDD|371259	pfam10824, T7SS_ESX_EspC, Excreted virulence factor EspC, type VII ESX diderm. T7SS_ESX-EspC is a family of exported virulence proteins from largely Acinetobacteria and a few Fimicutes, Gram-positive bacteria. It is exported in conjunction with EspA as an interacting pair.ED F8ADQ6.1/227-313; F8ADQ6.1/227-313;.	6.05332e-24
NZ_CP009483.1|WP_023369124.1|3273416_3274163_-|amino-acid-ABC-transporter-ATP-binding-protein	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.31443e-132
NZ_CP009483.1|WP_023369120.1|3272145_3272811_-|short-chain-dehydrogenase	gnl|CDD|181298	PRK08219, PRK08219, SDR family oxidoreductase.	4.27292e-113

Protein sequences

>NZ_CP009483.1|WP_023369114.1|3267404_3267755_-|hypothetical-protein
MLIAGVLCVCAAVASAVFGVWSLFHTRTADPTELALRAMAPTQLAAAVMLTAGGVVALVAAAPTALVVMVVCIAGAFGTLATGSWQSARYALRRGAATPKSADCGGDCAACTLSCR
>NZ_CP009483.1|WP_023369112.1|3266717_3267326_+|DUF179-domain-containing-protein
MVAPQEDPEDYMAPAAQRVRAGTLLLANTDLLEPTFRRSVIYIVEHNEGGTLGVVLNRPSETAVYNVLPQWAKLAAKPKTMFIGGPVKRDAALCLAVLRVGADPDGVPGLRHVAGRMAMVDLDADPDLLAPVVEGVRIFAGYSGWTIGQLEGEIERDDWIVLSALPSDVLVPPRADLWGQVLRRQPLPLSLLATHPIDLSRN
>NZ_CP009483.1|WP_023369110.1|3265289_3266609_-|MFS-transporter
MVEVGFVIRSQTQASAPVALWRSIRALPDFGRLLQLRIASQFGDGLFQAGLAGALLFNPDRATDPMAIARAFAVLFLPYSLLGPFAGALMDRWDRRLVLVGASIGRLAFIAGIGAILAFRGGDLLLLIGALLANGLARFVASGLSASLPHVVPREQVVTMNSVATASGAVAAFLGANFMLLPRWLAGGGDHGAAVVVFTAIVPVLIALLLSLRFAPRVLGPDDTKRAIHGSVVYAVITGWLHGVRTVVQQPTVAAALSGLAAHRMVVGINSLLILLLVHHMKDADVVGFGTALMFFAATGLGAFLANVLTPVLIRRWGRYATANGALIAASTIEIAGAGLVIPIMVACGFLLGVAGQVVKLCADSAMQIDVDDALRGHVFAVQDALFWVSFIASVTVAAALIPADGHAPAFVLFGSVIYLTGLVVHSIVGRRGQPVNGD
>NZ_CP009483.1|WP_080674240.1|3264393_3265278_-|TIGR03084-family-protein
MAGPGPIVADLRAESDDLDALVAPLPPQRWAEPTPAPGWTIAHQIGHLLWTDRVALTAVTDEAGFADVLTQAAADPAGFVDAGAEELAARPPGELLDDWRMTRGRLHDALLTVADGRKLPWFGPPMSAASMATARLMETWAHGLDVADALGISRPATNRLRSIAHLGVRTRDYAFFVNNLTPPAEPFRVELRGPDGDTWSWGPADAAQRVTGSAEDFCFLVTQRRALATLDIAAEGEDAQRWLTIAQAFAGPPAAGDERAPAREESRGPSTRQRAMSARQRAKRAAAHQPGSGR
>NZ_CP009483.1|WP_036394952.1|3263914_3264232_+|DUF2710-domain-containing-protein
MPGSGDRAELSDKDLVESVLRELSEAADKWEALVAQAETVTYSVDLGDIHAIANSDGRLLKLRLHPGVMTGYSHGELADRLNAAIAALREEAEAENQARYGGSLH
>NZ_CP009483.1|WP_036394844.1|3262621_3263854_+|hypothetical-protein
MAIFGRRSARQRLRRATEESLTIPAFSSPPDCTPWVIGGLWPAELSPNNAETAALAAYLKADLDRIVSSANDELRTLRSAVMLDSARRAAEAAVIDEARAWAVRRVESTLRQLRGQPAPPVVPRPSATAGSGGTDLERTRVLPAIKDEHPGAADDLASTRVLPVVEDAIGEEQPGAHEKEHVQLAAPPEAEIAVAESVAPARGVAAPESDDERLQRLLTFVARQEPRLNWAVGQRADGLTVLVTDLAHGWVPPGLMLPEGVQLLEPQRRSGGIAKLIGTTARLATYRPGDFLGWTSDFTPTTPSPKPRELPTSDNLASELSGVTRWRDGLPRIVHLLAQAAAAGGGVGEDEIDLLRVHLDTARHAVVAQYPNVDPALLLNCMLLAATESGVTGDPVSANYHFAWFRELNQ
>NZ_CP009483.1|WP_023369099.1|3262087_3262393_+|DUF2694-domain-containing-protein
MTDANPAFDTVHPSGHILVRSCRGGYMHSVTLSEGAMETDAETLAEGILRTADVSCLKALLEVRDEIIAAGHTPSASVPTDQDLDAAIEKLLAHQLRRRRR
>NZ_CP009483.1|WP_023369097.1|3261762_3262080_+|ESX-1-secretion-associated-protein
MADRIHVVPAHLREAAAHHQQTSEYLRTVPSSHAAILESLESLGPIFAELRGAGRELLELRRQCYEQQADDHADIAQSLRTSAAMWERHDQDAARDISRVFDPDR
>NZ_CP009483.1|WP_023369095.1|3260450_3261722_+|DUF4226-domain-containing-protein
MAGSRDRPQRGESASAPPDSGQATAADAIAGAEAALAHQNSVSSQLDLQVVSAILNAHLTAVEGRDALNQLQQETEAAVRTRSDLDTPAGARDFQRFLIGKLRDIREVVANASLDDTSKATLMAAWTSLYNASKNEAGAVGPGPATPARAAGDGGGQLADLLSDDPLLDSLLFDDPALPDGEAPMPGGSSPAPQMAPTTPGIPNLGGVPMPGLPTGATSPMPGLGWGGSPLSGLLRGSEPGLADRDERELDSGDPDHERAGHADDPTENREDRGDTDAQPSPDKPDSPPTGPTAVTLPNGETVTAANPQLAAAIKAAAGGVPIPDAFQQQGIALPPPGTPVTDPIDPARLEPGDIGFFVDRHTLALGRDKALLDGQIQQVSSIGGPSFLGWEHPPATATSTGPARAGVPTPTRPAAPSAASQY
>NZ_CP009483.1|WP_023369093.1|3260025_3260388_+|DUF4226-domain-containing-protein
MSEQAGSSPDAIAARQAVLGSQYQAITEADRVLAEALASAHATMRESIRRLDAIAADIERAVSDQAELAVDTPLGAREFQRFLLDKQREITTIVAGARELDHTKSAVLARLLAQYAGPAG
>NZ_CP009483.1|WP_036394963.1|3269127_3272055_+|leucine--tRNA-ligase
MTESPTTTPGSASGGTSSVRDAESDAPRYRYTAELAAGIERTWQDRWAREGTFNVPNPVGSLAAADGSPVPADKLFVQDMFPYPSGEGLHVGHPLGYIATDVFARYHRMKGNNVLHALGFDSFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLGHDSRRSFSTTDVEFYKWTQWIFLQIYNAWFDTAANKARPIAELCAEFDSGARTLDDGREWARLSAGEQADVIDSYRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAAALFSATIATGRRAGSRVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAVAWPDDVDPSWTYGAATPVDAVAAYRRAIAAKSDLERQESRDKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPVVEVIAGGDISQSAHTGDGVLVNSGYLDGMNVSDAKQAITARLESEARGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDDAALPVELPEVADHSPVLFDPDDADSEPSPPLAKATEWVHVELDLGDGLKRYSRDTNVMPQWAGSSWYELRYTDPHNSERFCARENEAYWMGPRPGEHGPEDPGGVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDARGSYVPADQVVERDGRFFYPDSGGETEVFQEFGKIGKSLKNSISPDEICDAYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLVVEEDTGETRVVDGTELDTDTLRALHRTIAGVSEDYAALRNNTAAAKLIEYTNHLTKEHRDAVPHAAVEPLVLMLAPLAPHLAEELWLRLGHAVSLAHGPFPEADPAYLVDETVEYPVQVNGKVRGRIVVGAEADNQAVEAAALADEKVQAFLGGATPRKVIVVPGRLINLVV
>NZ_CP009483.1|WP_023369120.1|3272145_3272811_-|short-chain-dehydrogenase
MPTALITGASRGIGSAIATALAPTHTLLLAGRPSERLDAIAERLGATTFPIELADDSTIEASCEVVDELDVLVHNAGLSIPGHVADSHVDEWRATFAVNVFGAVALTLALLPALRQTRGQVIFINSGAGRNVSPGMASYSASKFALRAFAESLRADEPDLRVTTIFPGRTDTDMQRELVEFEGGNYDPTRFLRAETVAAVVANVVATPPDGHVHEVVVRPR
>NZ_CP009483.1|WP_023369122.1|3272852_3273353_-|MarR-family-transcriptional-regulator
MADSESIAPEVTELAEGLHRALSKLFSILRRGDPNGAVAGELTLAQLSILVTLLDRGPIRMTDLAAHERVRTPTTTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRAVHAESLANRHAALAAMLSQLPHSDLDTLTNALAPLERLASGEPATATADDAARKQA
>NZ_CP009483.1|WP_023369124.1|3273416_3274163_-|amino-acid-ABC-transporter-ATP-binding-protein
MTGDARRAPVSLAARDIHQALGGNAVLRGVDLDVPAGTTAAVIGPSGSGKSTLLRTLNRLHEPDSGDILLDGRSVLRDNPNELRQRIGMVFQHFNLFPHRSVLANVALAPRRLRGLSGDAARDMALGHLERVGLKHKADARPGMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPEMVKDILALIADLGADGMTMVVVTHEMGFARSTSDAVVFMDHGKVVEAGPPEQIFEAAQTDRLQRFLAQVL
>NZ_CP009483.1|WP_036394846.1|3274159_3275971_-|amino-acid-ABC-transporter-permease
MSPRVGARTRSGHRLSAAAATILILASLATAAPAAADRHQCAPAGVDSATVLPANLSRAGVAGADDDTDTTATVVPLSSIDVNALGLGTPGVLTVGTLSDAPPNVCINSTGRFTGFDNELLRAIAAKLGLHARFVGTDFSGLLAQVASRRFDVGSASVKATDARRRTVAFTNGYDFGYYSLVVPPGSAITSFTDLAAGQRIGVVQGTVEESYVVDTLHLQPVKYPDFATVYASLKTHQIDAWVAPANQAAAAMRPGDPAVTVANTFSTEDFVAYAVARDNPALVDALNSGLDAVIADGTWAKLYSDWVPRTLPPGWKPGSKAVAAPTLPDFAAIAASQHRKPVQPAAPKSTLAQLRDSFFDWDMYRQAIPALFHTGLPNTLILTVSASAIGLAIGMALAVAGISHKRWLRWPARVYTDIFRGLPEVVIILIIGLGVGPIVGGLTNNNPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEAARALGFSYSAAMRLVVVPQGIRRVLPALVNQFIALLKASALVYFLGLVAKQRELFQIGRDLNAQTGNLSPLVAAGIFYLLLTIPLTHLVNYIDAKLRRGRARIDPQDPSEVVSSTIGQEMT
>NZ_CP009483.1|WP_023369128.1|3276011_3276773_-|GntR-family-transcriptional-regulator
MPKKYGIKEKDQVVSHILDLILTGKLRSGDRVDRNEIAQGLGVSRVPIQEALVQLEHDGVVSTRYHRGAFVERFDEATVLEHHELDGLLNGIASARAAANPTPRILGQLDALMRSLRMSKEPRTFSEVAHEYRRTVNDEYAGPRLRASIRASQNLIPRAFWLTYQNGRDDMLSFYEDEHSAIHRRDPEAARAACIGRSQLMAHTMLAELFRRRVFTPHGGIGPDQIPVRLAMAPEPSAVGALAGTREPSSIML
>NZ_CP009483.1|WP_023369130.1|3276893_3277682_-|LLM-class-F420-dependent-oxidoreductase
MTSAVHPDLPIRIGVQLQPQHAPHYGDIRDAVRRCEDIGVDIAFNWDHFFPLYGAPDGAHFECWTMLGAWAEQTSRIQIGALVTCNSYRNPELLADMARTVDHISDGRLVLGIGSGWKQKDYDEYGYEFGTAGSRLDDLAAALPRIKARLAKLNPPPTRDIPVLIGGGGERKTLRLVAEHADMWHSFTAADEFEAKAAVLNRHCADVGRDPAAIERSAAVTGGIADAEALVRLGVTLLTVGCDGPDYDLTAAEQLCRWRDGH
>NZ_CP009483.1|WP_023369132.1|3277718_3278633_-|alpha/beta-hydrolase
MTEISDDELTGLSEFDLLAENAEQAGATGPLPAVERVEADTAGGRISALRWGGSAPRVVFLHGGGQNAHTWDTVIVGLGEPALAVDLPGHGHSGWREDGDYSPQHNADALAPVLRGLAPAAEFVVGMSLGGLTAIRLGAVAPELVDELVVIDVTPSALQRHAEMTADQRGTVALMHGEREFPSFQAMLDVTTAAAPHREVKALRRGVFHNSRRLDNGNWTWRYDAIRSFPDFASLWDDVDALSAPITLVRGGNSGFVSDEDVAELARRATHFRGAHVVADSGHSVQSDQPRALVDILRGVLGRR
>NZ_CP009483.1|WP_023369134.1|3278779_3280399_-|PPE-family-protein
MSFLVLPPELNSALMFSGAGSGPLLDAAAAWEGLASDLGTAASSFSSVTSGLAGQAWQGPASQAMAAAAAPYSGWLNAAAVQAAGAAGQARAVVSAFEAAQAATVQPVMVALNRNSLVQMVLSNWFGLNAPAIAQLEADYEAMWAQDVSAMSGYYSGASAAAARLLPAQSLQDLLAALPNLGIGNIGSANLGNGNNGSVNAGNGNTGNQNLGSGNKGSFNIGSGNSGNANFGSGNIGNDNIGFGNTGDPSTSSNPGANFGIGNTGNGNFGVGNSGNLNVGGGNTGNGNLGFGLSGSNLIGFGNAYYNSATGQFTFAGLNSGVGNFGIGNSGTNNIGFFNSGHHNVGIFNSGTNPYSANAFTNIGFGNSGFFNFGFGNSGTGNTGVGNAGIVDTGFGNSGVQDTGFGNGGSFNTGFWNSGDTNTGIGNSGNTNTGFWNSGNVNTGLGATTDTGLTNSGFSNIGVGMSGFFNTAAGGTTNHNISGVFNTATGAITNGNSSGFGNTGVPGIIFGPALSGGNSGLFNNGTFKSGFFNLTGLFA
>NZ_CP009483.1|WP_023369136.1|3280582_3281692_-|inositol-3-phosphate-synthase
MSEYKPVRAPEAQPEVRVAIVGVGNCASSLVQGVQYYHNADENSTVPGLMHVRFGQYHVRDVKFVAAFDVDAKKVGFDLSEAIFASENNTIKIADVPPTDVVVQRGPTLDGIGKYYADTIELSDAEPVDVVQVLKDAKVDVLVSYLPVGSEEADKFYAQCAIDAGVAFVNALPVFIASDPVWAKKFADAGVPIVGDDIKSQVGATITHRVLAKLFEDRGVQLDRTMQLNVGGNMDFLNMLERERLESKKISKTQAVTSNLQREFKTKDVHIGPSDHVGWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGVGGPVIPASAYLMKSPPQQLPDDIARAQLEEFIIGPD

Crispr_ID: NZ_CP009483_11

• CRISPR_ID: NZ_CP009483_11
• CRISPR_location: 3373793-3373888
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_11

Consensus_repeat	Method
TGCCGTATCGAGCGTGCTTGCCGTATCGAGCGTGC	CRISPRCasFinder

spacers of NZ_CP009483_11

>11.1|3373828|26|NZ_CP009483|CRISPRCasFinder
TTGCCGTATCGAGCGTGCGGTGGTGC

CRISPR arrays and Neighbor proteins around NZ_CP009483_11

CRISPR arrays

The CRISPR arrays of NZ_CP009483_11

>merge|NZ_CP009483|11|3373793-3373888|CRISPRCasFinder
TGCCGTATCGAGCGTGCTTGCCGTATCGAGCGTGCTTGCCGTATCGAGCGTGCGGTGGTGCTGCTGTATCGAGCGTGCTTGCCGTATCGAGCGTGC

>NZ_CP009483|11|11|3373793-3373888|CRISPRCasFinder
TGCCGTATCGAGCGTGCTTGCCGTATCGAGCGTGC	TTGCCGTATCGAGCGTGCGGTGGTGC
TGCTGTATCGAGCGTGCTTGCCGTATCGAGCGTGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_080674085.1|3365140_3366364_-|cysteine-desulfurase	unknown	unknown	gnl|CDD|224029
NZ_CP009483.1|WP_080674086.1|3368681_3369443_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP009483.1|WP_023369316.1|3377182_3377512_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023369331.1|3382517_3382703_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023369291.1|3364037_3365144_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|378928
NZ_CP009483.1|WP_023369308.1|3371493_3373470_+|membrane-protein	unknown	unknown	gnl|CDD|225873
NZ_CP009483.1|WP_023369335.1|3385147_3386281_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023369313.1|3376011_3377040_+|glycosyl-transferase	unknown	unknown	gnl|CDD|366154
NZ_CP009483.1|WP_023369327.1|3381243_3381876_-|RES-domain-containing-protein	unknown	unknown	gnl|CDD|378053
NZ_CP009483.1|WP_023369300.1|3367916_3368579_-|peroxidase	unknown	unknown	gnl|CDD|239314
NZ_CP009483.1|WP_023369309.1|3374301_3375453_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_051480543.1|3378276_3379530_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023369297.1|3366742_3367888_-|acyl-protein-synthetase	unknown	unknown	gnl|CDD|282319
NZ_CP009483.1|WP_036394877.1|3381872_3382460_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036394872.1|3366341_3366740_-|iron-sulfur-cluster-assembly-scaffold-protein	unknown	unknown	gnl|CDD|143480
NZ_CP009483.1|WP_023369306.1|3370692_3371331_-|DUF5134-domain-containing-protein	unknown	unknown	gnl|CDD|375044
NZ_CP009483.1|WP_023369304.1|3369461_3370568_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226957
NZ_CP009483.1|WP_023369289.1|3363707_3364022_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|376348
NZ_CP009483.1|WP_023369333.1|3384000_3385092_+|cation-transporter	unknown	unknown	gnl|CDD|223131
NZ_CP009483.1|WP_023369337.1|3386588_3387869_-|MFS-transporter	unknown	unknown	gnl|CDD|340887

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_080674085.1|3365140_3366364_-|cysteine-desulfurase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	5.87349e-134
NZ_CP009483.1|WP_080674086.1|3368681_3369443_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	2.232e-100
NZ_CP009483.1|WP_023369291.1|3364037_3365144_-|ABC-transporter-permease	gnl|CDD|378928	pfam12704, MacB_PCD, MacB-like periplasmic core domain. This family represents the periplasmic core domain found in a variety of ABC transporters. The structure of this family has been solved for the MacB protein. Some structural similarity was found to the periplasmic domain of the AcrB multidrug efflux transporter.	2.18003e-12
NZ_CP009483.1|WP_023369308.1|3371493_3373470_+|membrane-protein	gnl|CDD|225873	COG3336, COG3336, Predicted membrane protein [Function unknown].	5.32145e-103
NZ_CP009483.1|WP_023369335.1|3385147_3386281_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	3.07063e-47
NZ_CP009483.1|WP_023369313.1|3376011_3377040_+|glycosyl-transferase	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	2.91065e-29
NZ_CP009483.1|WP_023369327.1|3381243_3381876_-|RES-domain-containing-protein	gnl|CDD|378053	pfam08808, RES, RES domain. This presumed domain contains 3 highly conserved polar groups that could form an active site. These are an arginine, glutamate and serine, hence the RES domain. The domain is found widely distributed in bacteria. The domain is about 150 residues in length.	1.45221e-08
NZ_CP009483.1|WP_023369300.1|3367916_3368579_-|peroxidase	gnl|CDD|239314	cd03016, PRX_1cys, Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by reducing and detoxifying hydrogen peroxide, peroxynitrite, and organic hydroperoxides. As with all other PRXs, a cysteine sulfenic acid intermediate is formed upon reaction of 1-cys PRX with its substrates. Having no resolving cysteine, the oxidized enzyme is resolved by an external small-molecule or protein reductant such as thioredoxin or glutaredoxin. Similar to typical 2-cys PRX, 1-cys PRX forms a functional dimeric unit with a B-type interface, as well as a decameric structure which is stabilized in the reduced form of the enzyme. Other oligomeric forms, tetramers and hexamers, have also been reported. Mammalian 1-cys PRX is localized cellularly in the cytosol and is expressed at high levels in brain, eye, testes and lung. The seed-specific plant 1-cys PRXs protect tissues from reactive oxygen species during desiccation and are also called rehydrins.	2.66805e-108
NZ_CP009483.1|WP_023369309.1|3374301_3375453_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	4.09274e-53
NZ_CP009483.1|WP_023369297.1|3366742_3367888_-|acyl-protein-synthetase	gnl|CDD|282319	pfam04443, LuxE, Acyl-protein synthetase, LuxE. LuxE is an acyl-protein synthetase found in bioluminescent bacteria. LuxE catalyzes the formation of an acyl-protein thioester from a fatty acid and a protein. This is the second step in the bioluminescent fatty acid reduction system, which converts tetradecanoic acid to the aldehyde substrate of the luciferase-catalyzed bioluminescence reaction A conserved cysteine found at position 364 in Photobacterium phosphoreum LuxE is thought to be acylated during the transfer of the acyl group from the synthetase subunit to the reductase. The carboxyl terminal of the synthetase is though to act as a flexible arm to transfer acyl groups between the sites of activation and reduction. This family also includes Vibrio cholerae RBFN protein, which is involved in the biosynthesis of the O-antigen component 3-deoxy-L-glycero-tetronic acid.	1.18725e-38
NZ_CP009483.1|WP_036394872.1|3366341_3366740_-|iron-sulfur-cluster-assembly-scaffold-protein	gnl|CDD|143480	cd06664, IscU_like, Iron-sulfur cluster scaffold-like proteins. IscU_like and NifU_like proteins. IscU and NifU function as a scaffold for the assembly of [2Fe-2S] clusters before they are transferred to apo target proteins. They are highly conserved and play vital roles in the ISC and NIF systems of Fe-S protein maturation. NIF genes participate in nitrogen fixation in several isolated bacterial species. The NifU domain, however, is also found in bacteria that do not fix nitrogen, so it may have wider significance in the cell. Human IscU interacts with frataxin, the Friedreich ataxia gene product, and incorrectly spliced IscU has been shown to disrupt iron homeostasis in skeletal muscle and cause myopathy.	5.07107e-32
NZ_CP009483.1|WP_023369306.1|3370692_3371331_-|DUF5134-domain-containing-protein	gnl|CDD|375044	pfam17197, DUF5134, Domain of unknown function (DUF5134). Proteins in this family are uncharacterized, but have been identified as members of a gene cluster for the synthesis of the tetramic-acid antibiotic streptolydigin, which inhibits bacterial RNA polymerase (RNAP).	4.65526e-25
NZ_CP009483.1|WP_023369304.1|3369461_3370568_-|ABC-transporter-permease	gnl|CDD|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	1.18283e-12
NZ_CP009483.1|WP_023369289.1|3363707_3364022_-|acyl-carrier-protein	gnl|CDD|376348	pfam00550, PP-binding, Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of the anguibactin system regulator AngR has the attachment serine replaced by an alanine.	2.58038e-05
NZ_CP009483.1|WP_023369333.1|3384000_3385092_+|cation-transporter	gnl|CDD|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	1.60794e-80
NZ_CP009483.1|WP_023369337.1|3386588_3387869_-|MFS-transporter	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.11264e-60

Protein sequences

>NZ_CP009483.1|WP_023369308.1|3371493_3373470_+|membrane-protein
MQTDVTADRSPSAVPASRSISWALAGLLLGLLGISGVLAGYGLASGARRYATAGNPYPGGFLCIAEPLGYFLASLATAVCLGALVYVVIASRPEHDGLIDAAAFRVHLVAERVSVAWLGLAVVMVVIQAAHDAGVAPSQLLGGGALLDAVGASEVARGWIVAAIGALVVAVTLRLITRWVGHFVLLIPTVIAVVATAVTGNAGQGPDHDYTTSAAIVFTLALATLTGLKTATAVATATPGRAVQVMQVACGALTLSYGAVLLYLLIPGWSFDSDFARLGLAAGLVVALVWLSDCWGLFVRPAGSGGARIAGALTMMAVMAAVAAMAIQTAPRYVTHQFSAWDVFLGYELPQPPNVVTLVTEWRFDSLVGTLGVVLAVGYVVAYVRLRKNGNAWPVGRLMAWLTGCVVLVFTSSSGLRAYGSAMFSVHMAEHMTLNMFVPVLLVLGGPVTLALRVLPAAGDGQPPGPREWLTWLLHSRVTAFLSHPITAFILFVASPYIVYFTPLFDILVRYHWGHEFMAVHFLIVGYLFYWAIIGIDPGPRRLPYPGRIGLLFAVMPFHAFFGIALMTTSSAIGSGFYQSVGLPWLPSIVADQHLGGGIAWGATELPIIIVIVALVAQWARQDRRVAAREDRHADSNYADDDLDAYNAMLRELSRMRR
>NZ_CP009483.1|WP_023369306.1|3370692_3371331_-|DUF5134-domain-containing-protein
MVDELLLRWLVTGLFVLSGANYVVAAIGQRGRWVYLVSNGLHLVMAIAMVVMIWPWGIHAPTTGPAAFFLLAAGWFIALTVVSAKTIAQWTAGSYHALMMLAMTWMYVVMNGHLLPGNPVTPHPASTAVSMPGMEMSAMPMPPESSQPGWVASVNWLWFLVFTIAAIVWTAVSLAGWRRGATECKRDILAQTGRISMALAMAIVFAALLSGG
>NZ_CP009483.1|WP_023369304.1|3369461_3370568_-|ABC-transporter-permease
MIVAVKNLVAERARLVFSVLGVGIAVLLVLVISGIFVGTTNRVTTYIDHYKGAVWVVQPGVSQMFKAVSWLPGDGRERLLTVPGVQSADPLLGSPSDFVHNGTHTAYFVLGYDTRTGVGGPWSLAQGRNVARSGEVVLDRVLATKNGIRLGDKVRIVDENFTVVGLSNQTAAVTNYYAFISLPDAARLLRAGNRVSYFLVRPRDGYTAEQVAAAIHRDMAGMDALTAASFAEKSRDIVVSMIGRPLKTMIAIAVLVGVALVGLTVLAVTNEQLRDFGVLRALGVRPIQLCRTVLAQAALIAGLGYLAGAAVAYGAQFLIADRLGDVTVEITPTMLATMAAATAVMAVLGSLIPVRRVVRIDPVTAFRH
>NZ_CP009483.1|WP_080674086.1|3368681_3369443_-|ABC-transporter-ATP-binding-protein
MRCPVCHHDASAPRCAQCRRPIPEDTSGPVLRLTDITVDYGGGATAVHALQGVDLSVERGEVVLVVGPSGGGKTTALLVMGLLLTPDGGTVQICGHDAGRLSERRRAELRLARLGYLFQDYNLLQSLTSVENVALPLRYAGVRKPAAIARARQLLHELDLGHRAHHRPAALSGGEKQRVAAARALAMGPDVILADEPTANLDSATGKKVSAQLASAAKAQDSAVVIVTHDARLEDIADRVLHLEDGRLLAATA
>NZ_CP009483.1|WP_023369300.1|3367916_3368579_-|peroxidase
MTLTIGSTAPDFEATTTDGPIKFHEWIGDSWAVLFSHPRDFTPVCTTELGYLATIKPEFDRRNVKIIGLSTDPLDSHAAWSKDIACTSGTAPNYPLIADTDYAVSKAYGMLPATIGGDPSDHPPAELATLRNVFVIDPNKTIMLVMIYPMTTGRNFDEVLRAIDSLQLLNNGLATPAQWRQGDDVIIAPWISDEQARHTYPDGWQGPLPYLRYVPSPQGL
>NZ_CP009483.1|WP_023369297.1|3366742_3367888_-|acyl-protein-synthetase
MDLVTMLGMPGDALRAPAYEARTSLTNALRKAFEHHFQHNGFYRAQCDAAGVTPADIHDYGDLHRIPLLPVGMFKQTGAHVLLTSGLEDIEMEIRSTGTSGVPSVARRDTLTVTRASVGLLGCYRDFFGISHGAGLFLCPSTAEIPEMGMVKVFNLLTGLLDDHSYLVRDYSFHPDEALARLRHWEGRMTRHIVGPPFIVARFMRYLELEAISLTLDPESLIIMLGGWKQYTGRSISRAEFNDKAERLLGIHRTRIRDMYGMIESNMLAIECEHQRKHVPPWCYVSIRDIADPTTELGTGQTGGIAILDALNTAYPGFLLSDDVGEVDEGTCRCGRTGQTVHFRRRRHGAELGCCAVSIEKYLDSREVVTECELAQTSRRA
>NZ_CP009483.1|WP_036394872.1|3366341_3366740_-|iron-sulfur-cluster-assembly-scaffold-protein
MSRYSPTVVDHFNNPRNCGRLANPDVSAFVGNPVCGDQILLTVRVEADAVSEVAFEAYGCSASLAVGSILTERLGGMTISDIAALDAARILQWSGGLGPDQHHVAVLGADAAHRLADNYRKGIHDDGTCFAG
>NZ_CP009483.1|WP_080674085.1|3365140_3366364_-|cysteine-desulfurase
MAPVSPVDGRAAVSVSPIHPGTDGVDGLYLDYAATAPLHPAAARAVHAGQQLLGNPSSGHAAGRAAADALRDARRSIARLLGVTPREVVLTSGGSEANALALWGTFAAHGFTGHLVTTSIEHSAVLENARALEKLDVAVTIVDPGPGGHVEAAAVAAAMRPDTVLVSVMHANNETGAIQPVHEIAALAAHAGVAFHMDAVHTAGKLSLDAVGASLISVSAHKFGGPRGVGALAVRNGHPLVPMVRGGPQENRLRAGTENVAGAMGMAAAVEVCLRRRSMGHRLGIRERREQLILGLAGTGGVHVNSTEPVLEETISVRFDGVRADTLADSLDMQGIYVSTGSACHAGHDAVSHVLTAMGLTERAARSTVRFSLGPEVTPDDIDRVVSVTTQAVQRLRGIAGTTGARQ
>NZ_CP009483.1|WP_023369291.1|3364037_3365144_-|ABC-transporter-permease
MIIAVKNLVVERARLMFSVLGVGIAVLLVLVISGIFVGTTNQVTTYIDHSKGAVWVVQPGVEQLFRAVSWLPADGRGRLLTVPGVQSADPILGQPSDFVHNGTQTAYFVVGYDTRTGAGGPWSLAQGRNVARSGEVVLDRVLASKNGIKLGDKVQIVDEDFTVVGLSNQTAALGNFYAFISLPDAARLLRAGNRVSYFLVQPRDGYTATQLAAAIHRDLPDMDALAAATFTDNSRAIIISMIGRPLKTMIAIAVLVGVALVGLTVLAVTNEQLRDFGVLRALGVRPIQLCRTVLAQAALIAGLGYLAGAAVAYGAQFLIADRLGDVTVEITPTMLATMAAATAVMAVLGSLIPVRRVVRIDPVTAFRH
>NZ_CP009483.1|WP_023369289.1|3363707_3364022_-|acyl-carrier-protein
MTENRSALILPEAGEVIGAFRDALEKVLAPEDLAQVDLVRVDSETPLLSLPIDSAVLMSLMTELEDRFAVFIDEEAAFAFETVADITDYVRRRLTDKAGRLAGA
>NZ_CP009483.1|WP_023369309.1|3374301_3375453_-|PPE-family-protein
MMDFGALPPEINSARMYAGPGAGSLLAAAAAWECLAADLYSLAAAYQSVISGLSVGSWLGPASMLMAAAAAPYVAWMNATAAQAEQAGIQAMAAVTAFNAVFSMTVPPPVIAENRAMLMTLVATDILGQNAAAIAATEAEYAEMWARDAAAMYGYAAASAAASTLTPFEEAPETTHADGLARQLALVGEVEAAAIRQLMSEVPRALRMLSEPAPWQWLVELWRGISPHLGTFRDIVSIGQNCVSVTNNTLAMTQMGAAMSRAVPAAVSEAAGAAAKAIAGGTTALGSASGGLGGSGLAAGLGRAASVGSLSVPQSWAAANHAINPAVRALPGTSLGSAAQSAPGHMLGGLPLGPTPSGGGSGVNGALRIPPRAYVMPRIPAAG
>NZ_CP009483.1|WP_023369313.1|3376011_3377040_+|glycosyl-transferase
MLLSGDNRRGLEEVFDHPRERHVSNPNALAGIRCTADAFASGRLGATLRSSAAIAMSQQLSVAIVIPAHNEERFIGKCLDACLSQTSAPDEIIVVNNKSSDNTVSIVRRYQEENPHIDIRLLNQNEHLGIAPTRNCGFDHARSQIIGRIDADSVVDTDWVETIRQCFQDSAIDAVTGPVHYYDIPLRGPIFRIDRMVRRNLHRTATDQRFLLGANMAIRTSAWQAVRHLTQLDLEDRLHEDIDLALTLFKNNFEIAYESTMVVGASGRRVECSPLDFFRYATRYTRTTKAHGVKSRSARITIAVLMLGYVPVRTLRFFYDAENNRFTRKRSGTGGGTKSTDY
>NZ_CP009483.1|WP_023369316.1|3377182_3377512_+|hypothetical-protein
MPANESSGLGMPVNWGIGTPDLPIPQLTGMPTLPNPFPAMPSLADLFCRPNGVPKLPATAELAALPDFSGTLAGLPTMAQLTAPLSQLTQLSGAAGGLNQPVNTASRHR
>NZ_CP009483.1|WP_051480543.1|3378276_3379530_+|hypothetical-protein
MLDALTEENVGTLFSNQGPPELVPELAPEPGPELPPEPDTSDISDNNPEQRLLRGSVVCFGTFSALAGMLGWLGHASPDPGDRLVASGSMFDDVSAHIAALGPDGGWQGSAAQAYLAQILAQSQRAKLMRDLDRRTRGLVSTQAQAVADTRAWLIHEMIIVAAVGISCLALEESGLPGGQQVSLAVAVVVCTAALGVAIYKLVWLKHTTSQNAHNLQGLTQRLTAIATTSPTLPDAIPGLPDVPAAPSPITGPPDDTGPLPKTPDISLALADLTGSPEFSVSDLPRPGFPDFGAPGLAIPEVAGLPHPATASELAALPDFSGALAAVPTMAQLTAALGQLTGLSGAAGGLSQLTTMAGQQAQMISALAQQGTQQHASLADQVTKDDDNAGAAAGATTAEHAPVDDASRSLQRRQRVL
>NZ_CP009483.1|WP_023369327.1|3381243_3381876_-|RES-domain-containing-protein
MSPRSKPKVPRTPPEKLTRQPDDSTSYTGTLWRIHRTEGEHVLPWNKLRTFGPLPSMRWDPHPDAEPSMRAEGVLYAAADVATGLAEVYQTTRVIDTRAGAPTLTAWKPQRKLRLLDLSGTWLLRNSASAALLAAPRSICRRWARAIYTTWPELDGLYVPSTMTGRPNIVLWTAAADSLPALPSFSRPLSHPLVWSITQAAASEIGYRIL
>NZ_CP009483.1|WP_036394877.1|3381872_3382460_-|hypothetical-protein
MKGSAAPALGALLAKHQIGLTVDEVLNELDSAFAAIPAAATLSAAEVDFLRKHAEPSMATAIDRWSADDERQARARVALRQLTSAVSGSVSIKEAAVLLGVDRSRVSRRITGKQLWAFDLQGTRRLPKWQFLGNELLPGLDLIVPAIPPGSTPAVLDVFMHTPQPDFDGRTPIEHLAAGGDASLVAGFIRDLGRW
>NZ_CP009483.1|WP_023369331.1|3382517_3382703_-|hypothetical-protein
MFLAVFASNLTVDGSRNDSHSNWRSWRPSSEGVNQHRGGWHLRAGKQLSCLAQSVVDALAG
>NZ_CP009483.1|WP_023369333.1|3384000_3385092_+|cation-transporter
MSDHHSETFSAAATYGGHNPSADDHGNHHHPKGWRAVVREIFAPHSHDAADSIDNALESSAAGIRAVKISLLVLGITAIAQIAVVTISGSIALAADTIHNFSDALTAVPLWIAFALSTKAATRRYTYGFGRVEDLAGLFVVAMITMSAIIAGYEAVVRLIHPQPVENVGWVALAGLIGFIGNEWVALYRIGVGRRIGSAALVADGLHARTDGFTSLAVLVAAGAVALGVPLADPIIGLVITVAILAVLRTAVRDVFHRLLDSVDPALIDTAEAVLATRPGVRSVRSLRMRWIGHRLHADAELDIDATLSLADAHRIAHDAEHGLIHAVPKLTTALIHAYPADHPNAAEQHRHGSEPPTEMSSF
>NZ_CP009483.1|WP_023369335.1|3385147_3386281_-|PPE-family-protein
MLDFAALPPEINSGRMYAGGGSGSLRAAAAAWEVLAADLYATAVEYLAVVSVLTEGPWRGSVSASMAAAAAPYVSWLATTASQAQHAAGQARAAAQAYEVAFQMTVPPAEVAANRTMLSWLVATNALGQNITAIATTESQYAEMWAQDAAAMYAYASASAAASQVAPFADPPPTTSEAGLTAQAAAVARAAESDAHLTTLSQLLSRVPLALQELASPMLSMDPPDWLDFIFVTAVPLILSSVSSCLGLTQSLASLSLVAGSAAQVAAGDAASLGSALAGGLGSAAGMSSAGAALSASLGGAGSIGGLSVPASWAALPAAGSAAAPLPTSWGVMPESTAGVPGMPGVPIAGTAGQGMGGAVPRYGFRPMVVPRPPAAG
>NZ_CP009483.1|WP_023369337.1|3386588_3387869_-|MFS-transporter
MGMVAQFRSFNRPSRVLMVNQFAINVGFYMLMPYLAGYLAGPLGLAAWAVGLVLGVRNFAQQGMFFVGGTLADRFGYKPMIVAGCLVRTGGFVLLVLAQSLPIVVIASAAMGFAGALFNPAARAYLAADAENRRIEAFAMFNVFYQSGILLGPLVGLALVAMDFRISVMAAAVVFAALSVAQLLALPPDKAGRAAGNARNSEKSSVIEDWRVVLGNRSVLWFAAAMIGAYVLEFQINLALPLHASRLAPQSQTSLVAVLFLISSLVTVAGQRHLTRWFGARWEPGRSLPVGVMLLTASFVPLAVVPNEQRFGIAAAVLALLLSASMLALAAAVVFPFELDRVVSLSGNRLVATHYGFYKTVVGIGLLIGNLATGALLSAAHRFNVDEFAWGALILVGLVAVAGLSRHGRHTAPVSGPGPALGVAAG

Crispr_ID: NZ_CP009483_12

• CRISPR_ID: NZ_CP009483_12
• CRISPR_location: 3550674-3551956
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 25 spacers

Consensus repeat of NZ_CP009483_12

Consensus_repeat	Method
GCCGCCGGTGCCGCCGATGCCGCC	CRISPRCasFinder

spacers of NZ_CP009483_12

>12.1|3550698|23|NZ_CP009483|CRISPRCasFinder
GGTTAGAGGCCGCCCCCCTCGCC
>12.2|3550745|39|NZ_CP009483|CRISPRCasFinder
GGAACCGCCGGCACCGCCGGCGCCGCCTCCCTGGCCGGG
>12.3|3550808|30|NZ_CP009483|CRISPRCasFinder
TTGGCCGCCTTGACCTCCGGGGCCGGCATT
>12.4|3550862|27|NZ_CP009483|CRISPRCasFinder
GGTGCCGCCGAGCCCGCCTTCGCCGCC
>12.5|3550913|27|NZ_CP009483|CRISPRCasFinder
GGCGCTACCCGCGCCGGTTCCGGGTTG
>12.6|3550964|15|NZ_CP009483|CRISPRCasFinder
GTTGCCTCCCAAGCC
>12.7|3551003|18|NZ_CP009483|CRISPRCasFinder
GCCGCTGTAGCCGCCGTA
>12.8|3551045|39|NZ_CP009483|CRISPRCasFinder
CTCGCCCCCGCCGCCGCCGTTGCCGTTGGCGGCCCCGAC
>12.9|3551108|45|NZ_CP009483|CRISPRCasFinder
GACACCGCCCTGGCCGCCGGCACCGCCGGCGTACCCGGCTGTTTC
>12.10|3551177|42|NZ_CP009483|CRISPRCasFinder
GGTGCCGCCGATGCCGCCCTGCCCCCCATTGCCGGCGGCACT
>12.11|3551243|45|NZ_CP009483|CRISPRCasFinder
GGTGCCGCCGGTGCCGCCGGTGCCGCCGGCGTAGCCCGGCGTTCC
>12.12|3551312|21|NZ_CP009483|CRISPRCasFinder
CGGACCACCGATACCGCCGTC
>12.13|3551357|21|NZ_CP009483|CRISPRCasFinder
AGGCCCTGGGGCGCCGCCGGT
>12.14|3551402|18|NZ_CP009483|CRISPRCasFinder
CATGGCGCCGGCCGATTC
>12.15|3551444|21|NZ_CP009483|CRISPRCasFinder
GCCACCGCCGACGCCGCCGGT
>12.16|3551489|21|NZ_CP009483|CRISPRCasFinder
ATTTCCGCCGGTGCCCGGGTT
>12.17|3551534|30|NZ_CP009483|CRISPRCasFinder
GGGCCCGCCCGCGAAGCCCGTTTCCTGGTA
>12.18|3551588|21|NZ_CP009483|CRISPRCasFinder
ACCGCCGCCGACGCCGCCCAC
>12.19|3551633|21|NZ_CP009483|CRISPRCasFinder
GGGGCCGCTGTCGCCGCCGGT
>12.20|3551678|21|NZ_CP009483|CRISPRCasFinder
AGCGGCGCCAGGCCGCTCGAG
>12.21|3551723|21|NZ_CP009483|CRISPRCasFinder
ACCGCCACCGCCGCCGCCGGT
>12.22|3551768|18|NZ_CP009483|CRISPRCasFinder
CACCCCAGCGCCGGACAG
>12.23|3551810|27|NZ_CP009483|CRISPRCasFinder
GGTCCCGCCGGCCCCGCCGATGCCACC
>12.24|3551861|21|NZ_CP009483|CRISPRCasFinder
GAAACCGCCGCCGCCGCCGTA
>12.25|3551906|27|NZ_CP009483|CRISPRCasFinder
GTAGTTGCCGGACCCTGAGATGGCGTC

CRISPR arrays and Neighbor proteins around NZ_CP009483_12

CRISPR arrays

The CRISPR arrays of NZ_CP009483_12

>merge|NZ_CP009483|12|3550674-3551956|CRISPRCasFinder
TCCGCCGGTGCCACCCTGGCAGCCGGTTAGAGGCCGCCCCCCTCGCCCGACGCGGTCCCGCCGGTGCCGCCGGAACCGCCGGCACCGCCGGCGCCGCCTCCCTGGCCGGGCGCACCGGCAGCGCCGCTGCCGCCTTGGCCGCCTTGACCTCCGGGGCCGGCATTGCCGCTGTAGTAGCCGGTGCCGCCGGTGCCGCCGAGCCCGCCTTCGCCGCCGACGCCGGCACCGCCCACGGTGCCGGCGCTACCCGCGCCGGTTCCGGGTTGGCCGCCGCCGCCGCCGCTGCCGCCGTTGCCTCCCAAGCCGCCGGCCGCGCCGGCGTAGGCGCCGCCGCTGTAGCCGCCGTACCCACCCTTGCCGCCCTGGCCGCCCTCGCCCCCGCCGCCGCCGTTGCCGTTGGCGGCCCCGACACCGGCCGCGCCGCCGGTGCCCCCGACACCGCCCTGGCCGCCGGCACCGCCGGCGTACCCGGCTGTTTCGTTGCCGCTGCCGCCGTAGCCGCCGGTGCCGCCGATGCCGCCCTGCCCCCCATTGCCGGCGGCACTGCCACCGGGACCGGGGGCGCCGCCGGTGCCGCCGGTGCCGCCGGTGCCGCCGGCGTAGCCCGGCGTTCCGATGCCGGTGTCGCCGTAGCCGCCCGGACCACCGATACCGCCGTCGCCGCCGTTGCCGCCGATGCCGCCAGGCCCTGGGGCGCCGCCGGTGCCGCCGGTGCCGCCGACGCCGCCCATGGCGCCGGCCGATTCGCGGCCGGCGCCGCCGTAGCCGCCGCCACCGCCGACGCCGCCGGTGCCGCCGTTGCCGCCGAGACCCGGATTTCCGCCGGTGCCCGGGTTGCCGCCGGTGCCGCCGGTGCCGCCGGGCCCGCCCGCGAAGCCCGTTTCCTGGTAGTCGCCCGGGCCGCCGTAGCCGCCACCGCCGCCGACGCCGCCCACGCCGCCGTTGCCGGCGGCTCCGCCGGGGCCGCTGTCGCCGCCGGTGCCGCCGGTGCCGCCGGAGCCGCCAGCGGCGCCAGGCCGCTCGAGTCTGCCGGCGCCGCCGAAGCCGCCACCGCCACCGCCGCCGCCGGTGCCGCCGGTGCCCCAGCTGTTGGGCACCCCAGCGCCGGACAGGCCACCGGCACCGGCCTTGCCGCCGGTCCCGCCGGCCCCGCCGATGCCACCCGGTCCGGTTTCGCCGTTGCCGCCGAAACCGCCGCCGCCGCCGTAGCCGCCGTCACCGCCGTAGCCGCCGTAGTTGCCGGACCCTGAGATGGCGTCAGCGCCGGTGCCGCCCGCCCCGCC

>NZ_CP009483|12|12|3550674-3551956|CRISPRCasFinder
TCCGCCGGTGCCACCCTGGCAGCC	GGTTAGAGGCCGCCCCCCTCGCC
CGACGCGGTCCCGCCGGTGCCGCC	GGAACCGCCGGCACCGCCGGCGCCGCCTCCCTGGCCGGG
CGCACCGGCAGCGCCGCTGCCGCC	TTGGCCGCCTTGACCTCCGGGGCCGGCATT
GCCGCTGTAGTAGCCGGTGCCGCC	GGTGCCGCCGAGCCCGCCTTCGCCGCC
GACGCCGGCACCGCCCACGGTGCC	GGCGCTACCCGCGCCGGTTCCGGGTTG
GCCGCCGCCGCCGCCGCTGCCGCC	GTTGCCTCCCAAGCC
GCCGGCCGCGCCGGCGTAGGCGCC	GCCGCTGTAGCCGCCGTA
CCCACCCTTGCCGCCCTGGCCGCC	CTCGCCCCCGCCGCCGCCGTTGCCGTTGGCGGCCCCGAC
ACCGGCCGCGCCGCCGGTGCCCCC	GACACCGCCCTGGCCGCCGGCACCGCCGGCGTACCCGGCTGTTTC
GTTGCCGCTGCCGCCGTAGCCGCC	GGTGCCGCCGATGCCGCCCTGCCCCCCATTGCCGGCGGCACT
GCCACCGGGACCGGGGGCGCCGCC	GGTGCCGCCGGTGCCGCCGGTGCCGCCGGCGTAGCCCGGCGTTCC
GATGCCGGTGTCGCCGTAGCCGCC	CGGACCACCGATACCGCCGTC
GCCGCCGTTGCCGCCGATGCCGCC	AGGCCCTGGGGCGCCGCCGGT
GCCGCCGGTGCCGCCGACGCCGCC	CATGGCGCCGGCCGATTC
GCGGCCGGCGCCGCCGTAGCCGCC	GCCACCGCCGACGCCGCCGGT
GCCGCCGTTGCCGCCGAGACCCGG	ATTTCCGCCGGTGCCCGGGTT
GCCGCCGGTGCCGCCGGTGCCGCC	GGGCCCGCCCGCGAAGCCCGTTTCCTGGTA
GTCGCCCGGGCCGCCGTAGCCGCC	ACCGCCGCCGACGCCGCCCAC
GCCGCCGTTGCCGGCGGCTCCGCC	GGGGCCGCTGTCGCCGCCGGT
GCCGCCGGTGCCGCCGGAGCCGCC	AGCGGCGCCAGGCCGCTCGAG
TCTGCCGGCGCCGCCGAAGCCGCC	ACCGCCACCGCCGCCGCCGGT
GCCGCCGGTGCCCCAGCTGTTGGG	CACCCCAGCGCCGGACAG
GCCACCGGCACCGGCCTTGCCGCC	GGTCCCGCCGGCCCCGCCGATGCCACC
CGGTCCGGTTTCGCCGTTGCCGCC	GAAACCGCCGCCGCCGCCGTA
GCCGCCGTCACCGCCGTAGCCGCC	GTAGTTGCCGGACCCTGAGATGGCGTC
AGCGCCGGTGCCGCCCGCCCCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_036395882.1|3557044_3558076_+|lipoprotein	unknown	unknown	gnl|CDD|240446
NZ_CP009483.1|WP_036395934.1|3546917_3548987_+|glycosyl-hydrolase	unknown	unknown	gnl|CDD|224389
NZ_CP009483.1|WP_023369651.1|3563693_3564545_-|nucleotide-diphosphate-sugar-epimerase	unknown	unknown	gnl|CDD|187578
NZ_CP009483.1|WP_023369621.1|3546360_3546882_+|TIGR04338-family-metallohydrolase	unknown	unknown	gnl|CDD|275137
NZ_CP009483.1|WP_023369617.1|3544737_3545577_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|378820
NZ_CP009483.1|WP_080674088.1|3558751_3559369_-|DUF5078-domain-containing-protein	unknown	unknown	gnl|CDD|374861
NZ_CP009483.1|WP_023369633.1|3553406_3555101_-|dihydroxy-acid-dehydratase	unknown	unknown	gnl|CDD|234861
NZ_CP009483.1|WP_036395926.1|3555656_3556925_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP009483.1|WP_036395887.1|3539015_3540098_-|lipoprotein	unknown	unknown	unknown
NZ_CP009483.1|WP_041803348.1|3549025_3549172_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023369641.1|3558221_3558704_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP009483.1|WP_036395929.1|3555223_3555514_+|hypothetical-protein	unknown	unknown	gnl|CDD|224848
NZ_CP009483.1|WP_036395938.1|3541633_3542362_-|pirin-family-protein	unknown	unknown	gnl|CDD|380375
NZ_CP009483.1|WP_023369607.1|3540203_3541586_-|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl|CDD|224428
NZ_CP009483.1|WP_023369645.1|3559365_3562236_-|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NZ_CP009483.1|WP_023369649.1|3563004_3563691_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP009483.1|WP_023369615.1|3543673_3544654_-|DNA-directed-RNA-polymerase-sigma-70-factor	unknown	unknown	gnl|CDD|236196
NZ_CP009483.1|WP_023369619.1|3545614_3546364_+|DUF2786-domain-containing-protein	unknown	unknown	gnl|CDD|378525
NZ_CP009483.1|WP_036395919.1|3562232_3562673_-|membrane-protein	unknown	unknown	gnl|CDD|283157
NZ_CP009483.1|WP_052492303.1|3542675_3543437_+|hypothetical-protein	unknown	unknown	gnl|CDD|237537

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_036395882.1|3557044_3558076_+|lipoprotein	gnl|CDD|240446	cd13431, LDT_IgD_like_1, IgD-like repeat domain of mycobacterial L,D-transpeptidases. Immunoglobulin-like domain found in actinobacterial L,D-transpeptidases, including Mycobacterium tuberculosis LdtMt2, which is a non-classical transpeptidase that generates 3->3 transpeptide linkages. LdtMt2 is associated with virulence and resistance to amoxicillin. This domain may occur in a tandem-repeat arrangement and is found N-terminal to the catalytic L,D-transpeptidase domain; this model represents the first (N-terminal) repeat in LdtMt2 and related proteins.	1.16604e-28
NZ_CP009483.1|WP_036395934.1|3546917_3548987_+|glycosyl-hydrolase	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	7.38576e-82
NZ_CP009483.1|WP_023369651.1|3563693_3564545_-|nucleotide-diphosphate-sugar-epimerase	gnl|CDD|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.23198e-46
NZ_CP009483.1|WP_023369621.1|3546360_3546882_+|TIGR04338-family-metallohydrolase	gnl|CDD|275137	TIGR04338, hypothetical_protein, putative metallohydrolase, TIGR04338 family. This protein family is restricted to the Actinomycetales, including Mycobacterium, Rhodococcus, Nocardia, Gordonii, and others. The invariant motif HEXXH, at the core of the best conserved region in the protein, suggests metallohydrolase activity, as does local sequence similarity in this region to other metallohydrolases.	1.39546e-75
NZ_CP009483.1|WP_023369617.1|3544737_3545577_+|alpha/beta-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	1.84743e-96
NZ_CP009483.1|WP_023369633.1|3553406_3555101_-|dihydroxy-acid-dehydratase	gnl|CDD|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NZ_CP009483.1|WP_036395926.1|3555656_3556925_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	2.20092e-72
NZ_CP009483.1|WP_023369641.1|3558221_3558704_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.27757e-16
NZ_CP009483.1|WP_080674088.1|3558751_3559369_-|DUF5078-domain-containing-protein	gnl|CDD|374861	pfam16877, DUF5078, Domain of unknown function (DUF5078). This family of unknown function is found in Mycobacterium spp.	2.27015e-72
NZ_CP009483.1|WP_036395929.1|3555223_3555514_+|hypothetical-protein	gnl|CDD|224848	COG1937, COG1937, Uncharacterized protein conserved in bacteria [Function unknown].	7.82314e-33
NZ_CP009483.1|WP_036395938.1|3541633_3542362_-|pirin-family-protein	gnl|CDD|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	1.46891e-73
NZ_CP009483.1|WP_023369607.1|3540203_3541586_-|YhgE/Pip-domain-containing-protein	gnl|CDD|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	1.59457e-65
NZ_CP009483.1|WP_023369645.1|3559365_3562236_-|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	0
NZ_CP009483.1|WP_023369649.1|3563004_3563691_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.00808e-18
NZ_CP009483.1|WP_023369615.1|3543673_3544654_-|DNA-directed-RNA-polymerase-sigma-70-factor	gnl|CDD|236196	PRK08241, PRK08241, RNA polymerase subunit sigma-70.	0
NZ_CP009483.1|WP_023369619.1|3545614_3546364_+|DUF2786-domain-containing-protein	gnl|CDD|378525	pfam10979, DUF2786, Protein of unknown function (DUF2786). This family of proteins has no known function.	5.17761e-09
NZ_CP009483.1|WP_036395919.1|3562232_3562673_-|membrane-protein	gnl|CDD|283157	pfam05423, Mycobact_memb, Mycobacterium membrane protein. This family contains several membrane proteins from Mycobacterium species.	2.154e-58
NZ_CP009483.1|WP_052492303.1|3542675_3543437_+|hypothetical-protein	gnl|CDD|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	0.00973912

Protein sequences

>NZ_CP009483.1|WP_041803348.1|3549025_3549172_-|hypothetical-protein
MATHEAGTELTCGHEGCGCRVRIEVPCHCSGAGEPYRCTCGDELVPVQ
>NZ_CP009483.1|WP_036395934.1|3546917_3548987_+|glycosyl-hydrolase
MTDDERFALLVGVMGAGDWWPLRDERIPPDVSMSAGYVPGIPRLGVPALRMSDAGLGVTNPGYRPGDSATALPAGLALAAGFDPALARATGEVIGRQARSRGFNVQLAGAINLTRDPRNGRNFEYLSEDPLLSAAMAAEQIIGIQRQGVISTTKHYSLNCNETNRHWLDAVIDPDAHRESDLLAFEIAIERAQPGAVMTAYNKVNGDYAAANAVLLNDVLKAAWGYRGWVMSDWGGTPGWECALAGLDQECGAQIDAVLWGAEAFGDRLRAAYSGGLLPKERLSDMVRRILRSMFAVGIDRWKPVPAPDMQAHNAIALQVARQGIVLLQNRGLLPLTLGSGVRIAVIGGYAQVGVAAGYGSSTVVPPGGYASVIPIGGSGLQAGLRNLYLVPPSPLDELRRQFPGVPIDFDPGISPVEAVMAARRAEVAIVFAIRPEGEGFDSADLSLPWGQDAVISAVAAANPNTVVVLETGNPVAMPWRDRVNAIVQAWYPGQAGATAIAEVLAGQVNPSGRLPITFPADLGQTPRPKLPDAAPGTPTTIDYHEGADVGYRWFARTGQAPMFAFGHGLSYTSFEYRDLAVTGGDTVTASFSVVNTGDRYGSDIAQLYLTTVPGAQRLRLLGFQRVDLEPGQVVRVSIAADPRLLGGYDGRAGCWRITAGRYAVAVGASAVALTLAAEVELAGRAFGR
>NZ_CP009483.1|WP_023369621.1|3546360_3546882_+|TIGR04338-family-metallohydrolase
MTRADSSGRDSQRARVYAAEEFVRTLFDRAVEHGSPGVDFFGTQLTLPPEGRFASVASVQRYVDDVLALPAVRRNWSSVSPLRVRARRAATAAHYENRDGAGTIAVPDRDTAGWAMRELVVLHEVAHHLCRVPPPHGPQFVATMCELAELVMGAEAGHILRVVYAKEGVRWTD
>NZ_CP009483.1|WP_023369619.1|3545614_3546364_+|DUF2786-domain-containing-protein
MTDDKMLARIAALLRQAEGTDNPHEADAFMAAAQRLATAASIDLAVARSHSATRSAAQSPTQRTITIGTAGVRGLRTYVQLFVLIAAANDVRCDVASNSTFLYAYGFPEDIDATHALYASLVVQMVRASDAYLASGAHRPTPTITARLNFQLAFGARVGQRLAEAREQARREVTADRGRAPRTAIALRDKEVELRDYYRGASRARGTWQAHRASAGYSSAARRAGDRAGRQARLGQSPELPGARTALDR
>NZ_CP009483.1|WP_023369617.1|3544737_3545577_+|alpha/beta-hydrolase
MNATRTERNFAGVGGVDIVYDVWTPDTAPNAVVVLAHGLGEHARRYDHVAQRFGEAGLVTYALDHRGHGRSGGKRVLVRDISEYTADFDTLVRIATRENPGLKCIVLGHSMGGGIVFAYGVERPDNYDLMVLSAPAVAAQDLVSPVVALAAKVLGVVLPGLPVQELDFTAISRDPQVVADYQNDPRVYHGRVPAGIGRALLQVGETMPRRAPALTAPLLVVHGTGDRLIPIEGSRRLVECVGSGDVELKEYPGLYHEVFNEPERNQVLDDVVGWITKRL
>NZ_CP009483.1|WP_023369615.1|3543673_3544654_-|DNA-directed-RNA-polymerase-sigma-70-factor
MGLLAQDNDLGGDFSARAEPYRRELLAHCYRMTGSLHDAEDLVQETLLRAWKAYDRFEGKSSIRTWLHRIATNTCLSALEGRQRRPLPTGLGTSSADPTAELVERGEVPWLEPLPEPTDDPADPSVIVGSRESVRLAFVAALQHLSPRQRAVLLLRDVLQWKSAEVAEAIGTTTVAVNSLLQRARSQLETVRPSAEDRLSAPDSPQAQDLLARYIAAFETYDIDRLVELFTAEAIWEMPPYVGWYRGAQDIITLIHQQCPAESPGDMRMLPLVANGQPAAAMYMRAGQRHVPFQLHVLDMVDGRVSHVVAFLDGSLFPKFGLPPSL
>NZ_CP009483.1|WP_052492303.1|3542675_3543437_+|hypothetical-protein
MGGAGGAAGLFGNGGAGGRGGMGGVGAAVPNSVAGDGGMGGAGGAAGLFGDGGAGGPGGDGGAAAAVPGSTAGKGGVGGIGGAGHLFGSGGAGGQGGHGGAGGLSSANTGGDGGDGGTGGRGGLWGNGGAGGSGGQAGAGLVGDGTSGMGGAGGAARLFGNGGAGGAGGGSGGGGTAGMGGAGGRGGLFIGDGGRGGNAGATGGFGGGANGGGGGDAIFFGNGGDGGNGTGGKPGGKGGSAGPFGHNGMNGLP
>NZ_CP009483.1|WP_036395938.1|3541633_3542362_-|pirin-family-protein
MPATVEIRRAAERAVTTTDWLESRHCFSFGDHYDPDNTHHGLLLVSNDDIVQPGTGFATHPHRDMEIVTWVLKGELTHRDSTGTHGVIYPGLAQRMSAGSGIRHSETNESATRPVHFVQMWIVPDQTGIAPSYQQHDIGDDLSNGALVTIASGINGHDDAAITLHNRSAALHAARLRPGDMVDVPAAPYLHLFVTRGRIDLDGAGELAEGDAVRCTDTGARRLTANCPAEVLVWEMHANLGS
>NZ_CP009483.1|WP_023369607.1|3540203_3541586_-|YhgE/Pip-domain-containing-protein
MSQSHPRHAAPNPKRSIKSVRTVRFWAAPILITLALMSALAALYLGGILNPATNLRHFPIAVVNQDAGPTGKQIVEGLVAGLDKDKYDLRVVSHDEAKRLLDRAEVYGSAVIPPTFSSALRDYAMSAVQPTHADRPTITISTNPRAGTLGSSIAAQTLTQAMAVVNSKVGQRLTADVAAQTGGAPLAGAAALGLTNPIDVKSTVYNPLPNGTGNGLSAFYYALLLLLAGFTGSIVVSTLVDSMLGYVPAEFGPVYRFGEQVRISRFRTLLLKWGLMTVLALLTSAVYLAIAHGLGMPVSLGWQLWLYGVFAIIAVGVTSSSLIAVLGSMGLLVSMLIFVIFGLPSAGATVPLEAVPPFFRWLATFEPMHQVFLGVRSLLYLDGHADAGLSHALAMTSIGLVIGLLLGGIITHLYDRKGFHRIPGAVELAIAAEHQAQHQARERARAGAVEGTSENPSEQT
>NZ_CP009483.1|WP_036395887.1|3539015_3540098_-|lipoprotein
MLTPSASLRRLAACLALVAACATLTATTGRPVAHAADGREMLEHAIATTKGSYLVYNFGGGHPMPLLNGDGGRYEMNNGGHLMIIKNASQRLQPHLLVDTHTGDQARCEHNAGARTNEGLWQASEIYAPLQAWQRMGQPTIAINANFFDVRPQKGGSWRSTGCSSPLGAFVDNTHGQGRANQAVTGTVAYAGKQGLSGGNETWTSLTTMIIPAGGAPYVLRPKGREDYDLATPVIQDLLNKNAKFVAVAGIGLLSPGNTGQLHDGGPSAARTALAYAKQKDEMYIFEGGNYTPDNIQDLFRGLGSDTAILLDGGGSSAIVLRRDTGGMWAGAGTPKGSCDTREVLCDSHERALPSWLAFN
>NZ_CP009483.1|WP_023369633.1|3553406_3555101_-|dihydroxy-acid-dehydratase
MPEADIKPRSRDVTDGLEKAAARGMLRAVGMGDEDFAKPQIGVASSWNEITPCNLSLDRLAKAVKEGVFAAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVETVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLAAVFLYAGSILPGLAKLSDGSEREVTIIDAFEAVGACARGLMSREDVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTREAFENAIAVVMAFGGSTNAVLHLLAIAHEAGVELALDDFNRIGSKVPHLADVKPFGRHVMSHVDHIGGVPVVMKALLDAGLLHGDCLTVTGQTVAENLAAIAPPDPDGKVLRALSNPIHPTGGITILRGSLAPEGAVVKTAGFDSEVFEGVARVFDGERAALDALEDGTITGGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGLCVGHIAPEAVDAGPIAFLRDGDRIRLDVTSRTLDVLADADEFADRQQDFAPPPPRYQTGVLAKYVKLVGSAAGGAVCG
>NZ_CP009483.1|WP_036395929.1|3555223_3555514_+|hypothetical-protein
MTTDYGYSQQKDNYAKRLRRIEGQVRGIARMIEEDKYCIDILTQISAINSALRSVALNLLDEHLNHCVTRAVAEGGTEADSKLAEASAAIARLVRS
>NZ_CP009483.1|WP_036395926.1|3555656_3556925_+|MFS-transporter
MTADTRTVAPAAGPWTPRIAAQLAVLAAAAFTYVTAEILPVGALSAIARNLNISIVLVGTLLSWYALVAALTTVPLVRWTAHWPRRRTLVVALVCLTVSQLISALAPNFAVLAAGRVLCAVTHGLLWSVIAPIATRLVPASHAGRATTSIYVGTSLALVVGSPLTAVMSLMWGWRLAAVCVTVAAAVVTVAARLLLPELVLSADQLQHVGPRSRHHRNRALIIVSLITMIGVTGHFVSYTYIVVVIRQVVGVHGPSQAWLLAAYGVAGVIAVALVARPLDRRPKGAVIFCVAGLTVAFVVLTGLAFGGDRAPVTTLVVGTGAIVLWGAAATAVSPMLQSAAMRSGADDPDGASGLYVTAFQLGIMAGSLAGGLLYERSVALMLTASAILMGVALVAVSAVRRVFEAADDAASNTGRATSHPN
>NZ_CP009483.1|WP_036395882.1|3557044_3558076_+|lipoprotein
MSRWTRARSRGSRVRRLRRVSLFAAVNVAGVVSVLLLGAGPALADPDQVPGDPDVVAPAEPADPAAPAPDPLALPPADPLAPPPPDPLAIPVAAGPVAGQDPTPFVGDPPFRPPTFNPVNGAMVGVAKPIIINFQVPIADRPMAESAIHISSIPPVPGKFYWMSPTQVRWRPLQFWPANTAVNIDAAGTRSSFRTGDALVATADDATHQMTITRNGVVQQTFPMSMGMSAGNHQTPNGTYYVLEKFPTVVMDSSTYGVPVNSAQGYKVTVSDAVRIDNSGNFVHSAPWSVGDQGKRNVSHGCINLSPTNAKWFYDNFGSGDPVVVKNSVGTYNKNDGAQDWQI
>NZ_CP009483.1|WP_023369641.1|3558221_3558704_+|MarR-family-transcriptional-regulator
MTGPPSGITALDERIAFLLSQLGSYSDGEFHRRLAPSGVEPRAYAVLMALAADDGQSQRQLSARLGIHRNVMVTVIDELERKRLVKRLRHPEDRRAFAITLTDKARRLLPALDESGQALDEEMSAPLSLVERDTLRKLLRRMAAGAGLIPGVHPRMSERG
>NZ_CP009483.1|WP_080674088.1|3558751_3559369_-|DUF5078-domain-containing-protein
MRTFLGHQRRSGLVIPGCRRHLLPTSGTWCASSQSAGRACRSQAGEDLSWTSGFRRNCPGAGIRATVAALAVSAGLAAAPGTASADGTDDYPIPHRMIVTTCTAEQIMAAARDVEPVYYQRYMIDYHNHSAEIQEATRHQMHWFYGLGVADRRAYSEQFVTHFADPLTLAWPNHAKLFFNNKGVAAHTTDICGQYPPDDPSVWNW
>NZ_CP009483.1|WP_023369645.1|3559365_3562236_-|MMPL-family-transporter
MSNRHSERPVLARAIRLLSVPIIVFWLALAAVTNTVVPQLEIVGRHHSVSLTPHDAPSSIAMKRMGAVFGEYDSDSAAMIVLEGDAPMGGAAHDYYDGLVRQLEQDTKHVQHVQNYWGDLITAAGSQSADGKSAYVQLNLAGDVGQPLGNESVEAVRDIVARSHPPAGVRAYVTGQAPLTTDLTDAGEKSMVKITVITLVVITVMLLIVYRSVGNLLPVLLVVVIEMCAARGVVAVIGNAGMLGLSTFATSLLTSLAIAAGTDYAIFLVGRYHEARQAGEDRETAYYTAYRGIAHVILGSGLTVAGAMLCLHFTRLNYFSSMGIPSAIGLAVVIAASLTLGPAVLTAGSRLGLLDPKRTINTRGWRRVGTAVVRWPVPILAGAIAVALVGLLALPGYRTNYNDRRYIPASLPTNIGYAAAERHFTAARMNPDMLLVETDHDLRNPSDMLVLDRIAKNIFRVPGIARVQSITRPLGTPIEHSSIPFQISMQSVSTTENLQFLKDRMADMKKMSDDFGVMVAAMERMMDLMRQLSDTTHHMVADTEEMKATTDEMRDHLADFDDFFRPLRSYFYWEQHCFNIPICWAMRSVFDGLDGVDKLTDNLDLLLDDLKNMDAVLPQLLDQLPPMIVVSKSMQTTLLTMYSSFDGMITQIERMTNTATAMGQAFDAAKNDDFFYLPPEAFQNPDFQRGLKLMVSPDNKSARIIITHDTDPATPEGISHVDAELQAAHEAVKGTPLAGAKFYLGGTAATYKDIQTGAKWDLMIAATAAITLIFIVMLVITRALFASFVIIGTVVLSLGASFGLSVLLWQYILGIELHWMTMAFSVIVLLAVGSDYNLLVVSRFKEEITAGLKTGIVRSMGATGGVVTAAGLVFAVTMAAMATSELRAIGQGGTTIGLGLLFDTLVVRSLMTPSIAAVLGRWFWWPLQVRSRPGHVAPLPAPARPNPVALQPVPAE
>NZ_CP009483.1|WP_036395919.1|3562232_3562673_-|membrane-protein
MTAILSALKRLWIPLVVSLTVATSGFTVYRLHGIFGAAGFSAISNGHADEIVPFNPKQVRYEVVGPPGTTGSISYLDENAAPQQARFTMLPWTHTFTTTIPAVFANLVAQGDSNAIGCRISVNGEIKEQQYATEVNAQTFCLVKSA
>NZ_CP009483.1|WP_023369649.1|3563004_3563691_-|class-I-SAM-dependent-methyltransferase
MTAPGDFTFESAYRGEVPSLGSGPKPPWSIGEPQPELAALIEQGKFHGDVLDAGCGEAAISLQLAELGYTTVGLDLSPTAIELARAEAAKRGLSNATFAVADISDFTGYPPGSEGRFGTIVDSTLFHSLPVEAREGYLQSVVRAAAPGASYFVLVFDRASMPEGPANAVTEDELRELVGRYWAIDEIKPARLHGNLPESFSALPLGDLRDEPNGRKSVPGWLLSAHLP
>NZ_CP009483.1|WP_023369651.1|3563693_3564545_-|nucleotide-diphosphate-sugar-epimerase
MTTILVTGATGNVGRPLVTALADAGVTVRAVSRHPDSAGLPAGVAVLTSAADGLRGADAVFLNSRALGDHLVAVVDRARDEGVTRLVVLSAINADDDFSVQPSRFRGDRNQEVEQLAVDSGLEWVSLRPTMFVSNLVGMWSTQLQAGDVVRGPYAAASCAPIVEEDISAVAAQALLTDRLVGRRIALTGPQSFTNAELVAEIGSVVHRRLRYQEVPPEQVRNKFVALGFSPGFADAYIGFLSATVDGPAAVTREVENILGRPAQSFAAWVADHRELFTRSQGG

Crispr_ID: NZ_CP009483_13

• CRISPR_ID: NZ_CP009483_13
• CRISPR_location: 3751265-3751372
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP009483_13

Consensus_repeat	Method
CCCTTTGGAGGCGGCGGCCACGGTGGTGGT	CRISPRCasFinder

spacers of NZ_CP009483_13

>13.1|3751295|48|NZ_CP009483|CRISPRCasFinder
GGCGGCCACGGTGGTGGTGGCCACGGCGGCTTCGGCGGTGGGCACGGA

CRISPR arrays and Neighbor proteins around NZ_CP009483_13

CRISPR arrays

The CRISPR arrays of NZ_CP009483_13

>merge|NZ_CP009483|13|3751265-3751372|CRISPRCasFinder
CCCGTCGGGGGCGGCGGCCCCTTTGGAGGCGGCGGCCACGGTGGTGGTGGCCACGGCGGCTTCGGCGGTGGGCACGGACCCTTGGGAGGCGGCGGCCACGGTGGTGGT

>NZ_CP009483|13|13|3751265-3751372|CRISPRCasFinder
CCCGTCGGGGGCGGCGGCCCCTTTGGAGGC	GGCGGCCACGGTGGTGGTGGCCACGGCGGCTTCGGCGGTGGGCACGGA
CCCTTGGGAGGCGGCGGCCACGGTGGTGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023369989.1|3758426_3759230_+|uridine-phosphorylase	unknown	unknown	gnl|CDD|350158
NZ_CP009483.1|WP_080674090.1|3744829_3745144_+|hypothetical-protein	unknown	unknown	gnl|CDD|222853
NZ_CP009483.1|WP_023369970.1|3747579_3748248_+|pyroglutamyl-peptidase-I	unknown	unknown	gnl|CDD|171894
NZ_CP009483.1|WP_023369985.1|3756307_3756976_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP009483.1|WP_042313723.1|3751615_3753031_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP009483.1|WP_036396187.1|3759784_3760540_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|274422
NZ_CP009483.1|WP_036396176.1|3746784_3747510_-|membrane-protein	unknown	unknown	gnl|CDD|223505
NZ_CP009483.1|WP_036448167.1|3741489_3742530_-|integrase	unknown	unknown	gnl|CDD|271183
NZ_CP009483.1|WP_023369974.1|3749110_3749683_+|dCTP-deaminase	unknown	unknown	gnl|CDD|234753
NZ_CP009483.1|WP_023369960.1|3742529_3743480_-|integrase	unknown	unknown	gnl|CDD|271178
NZ_CP009483.1|WP_080674250.1|3741066_3741213_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023369995.1|3760551_3760926_+|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NZ_CP009483.1|WP_036444000.1|3748365_3749022_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_036396191.1|3740535_3740850_-|DUF2563-domain-containing-protein	unknown	unknown	gnl|CDD|287754
NZ_CP009483.1|WP_023369991.1|3759450_3759696_+|DUF4190-domain-containing-protein	unknown	unknown	gnl|CDD|379388
NZ_CP009483.1|WP_023369980.1|3753107_3754457_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223936
NZ_CP009483.1|WP_023369987.1|3757248_3758430_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223523
NZ_CP009483.1|WP_023369982.1|3754594_3755272_+|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238089
NZ_CP009483.1|WP_036396178.1|3745193_3746249_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP009483.1|WP_023369984.1|3755295_3756075_-|membrane-protein	unknown	unknown	gnl|CDD|224931

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP009483.1|WP_023369982.1|3754594_3755272_+|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.5e-17	58.1	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023369989.1|3758426_3759230_+|uridine-phosphorylase	gnl|CDD|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	3.196e-73
NZ_CP009483.1|WP_080674090.1|3744829_3745144_+|hypothetical-protein	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.67461e-14
NZ_CP009483.1|WP_023369970.1|3747579_3748248_+|pyroglutamyl-peptidase-I	gnl|CDD|171894	PRK13195, PRK13195, pyrrolidone-carboxylate peptidase; Provisional.	5.70605e-125
NZ_CP009483.1|WP_023369985.1|3756307_3756976_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.68589e-20
NZ_CP009483.1|WP_042313723.1|3751615_3753031_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	9.05237e-15
NZ_CP009483.1|WP_036396187.1|3759784_3760540_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	3.83381e-19
NZ_CP009483.1|WP_036396176.1|3746784_3747510_-|membrane-protein	gnl|CDD|223505	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism].	1.28341e-23
NZ_CP009483.1|WP_036448167.1|3741489_3742530_-|integrase	gnl|CDD|271183	cd01182, INT_RitC_C_like, C-terminal catalytic domain of recombinase RitC, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	8.17395e-55
NZ_CP009483.1|WP_023369974.1|3749110_3749683_+|dCTP-deaminase	gnl|CDD|234753	PRK00416, dcd, deoxycytidine triphosphate deaminase; Reviewed.	1.01865e-98
NZ_CP009483.1|WP_023369995.1|3760551_3760926_+|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.000116581
NZ_CP009483.1|WP_023369960.1|3742529_3743480_-|integrase	gnl|CDD|271178	cd00797, INT_RitB_C_like, C-terminal catalytic domain of recombinase RitB, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	5.76037e-43
NZ_CP009483.1|WP_036396191.1|3740535_3740850_-|DUF2563-domain-containing-protein	gnl|CDD|287754	pfam10817, DUF2563, Protein of unknown function (DUF2563). This family of proteins with unknown function appears to be restricted to Mycobacterium.	3.38906e-38
NZ_CP009483.1|WP_023369991.1|3759450_3759696_+|DUF4190-domain-containing-protein	gnl|CDD|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	0.00187864
NZ_CP009483.1|WP_036396178.1|3745193_3746249_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.44934e-56
NZ_CP009483.1|WP_023369987.1|3757248_3758430_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	2.22293e-34
NZ_CP009483.1|WP_023369982.1|3754594_3755272_+|ArsR-family-transcriptional-regulator	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.16602e-21
NZ_CP009483.1|WP_023369980.1|3753107_3754457_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl|CDD|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_CP009483.1|WP_023369984.1|3755295_3756075_-|membrane-protein	gnl|CDD|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	2.02585e-09

Protein sequences

>NZ_CP009483.1|WP_023369974.1|3749110_3749683_+|dCTP-deaminase
MLLSDRDLRAEISAGRLGIDPFDDSLVQPSSVDVRLDCLFRVFNNTRYTHIDPARQQDELTSLVEPATGDPFVLHPGEFVLASTLELFTLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPIALWPGMKIGQLCILRLTSPAEHPYGSSGVGSKYQGQRGPTPSRSYVNFIRST
>NZ_CP009483.1|WP_036444000.1|3748365_3749022_+|hypothetical-protein
MGRHSLVRERRRSPAVLAAVLAPAAVFFAVAGDVGPLDARVVDQGDGPCCVEIVAATPLALVSRMPGSEAGMGLGGGQFAAASRWRVDTRSRALPPGAAPEQGLQVKTILVARSLSALFPEIHEIGGVRADALRWHPNGLALDVMIPDPGSADGIALGNQIVGYVLLNASRFGIQDAIWRGVYYTPEGARSTGAGHYDHVHITTTGGGYPTGEEIYLR
>NZ_CP009483.1|WP_023369970.1|3747579_3748248_+|pyroglutamyl-peptidase-I
MSQVLVTGFGAYGNTPANPAQLTAEALDGRIIAGATVTARIVPNVFFESIAVTQQAIADVRPDLVVMLGEYPGRAVITVERLAQNINDCGRYGLADNAGTVLVGEQTDPAGPVAYHATVPIRAMVVAMRKAGVPADISDAAGTFVCNHLMYGVLHHIAKNGLPIRAGWIHLPCLPSVAALEHNLGAPSMSVETAVAGVAAGIEAAVRQLSDIGKPVRSRLQI
>NZ_CP009483.1|WP_036396176.1|3746784_3747510_-|membrane-protein
MSIVTTAASLVAFPVVAGIIGGVVAVVRSPSPALVSGVQHFAAGVVTAAVAGEVLPDLRARGSLWLIVVGFSAGVAVLVGLRHFDGDEGSGGEGSGGALPVAFLAVVAVDLFIDGLLVATGATVSRRTALIIALALTVEVLFLGLSVALRLTGSGVPRVRAAVTTGGVSLVTAVGAVLGALLLGGASAAVLTLVLAFAAAALLWLVVEELLVEAHETPERPWMAVMFFAGFLILYCLGVME
>NZ_CP009483.1|WP_036396178.1|3745193_3746249_+|serine/threonine-protein-kinase
MTAATRAAGKIIAGRYEVRKALGSGAFGEVYEVFDHNLKQVCALKIHNRMVAGPWTEAQILRQLDGEYILKVLNADLAEGAPYVVTHLATNGTIADQIQPDVGVPITAAVRWARQACQGVARIHDQKLLHRDLKPENLFIDGRHDVLVGDLGLAQLQDENGLADAAGSIPTMAPEIARIGAPGQNPTTARVYSIAADVYSLGATLFWMLAGAQPVPGTSSYDDIWRASQPDLWEVAPHVPQGLRDIVNRSIAREPVKRYASAAGFDSALGGWSPPPRLWTRVKPHPGHEQCFSGTKGASLLAVCAIPTGVRTQLNIVAYHSASGRAVTKARRTVPRSGLSAGLRSAFHACN
>NZ_CP009483.1|WP_080674090.1|3744829_3745144_+|hypothetical-protein
MRLNSDRGCQYTSAQLARFAREHNLARSVGRTAVCWDNAQAESFWATLKVEFYDRCLWPTKAAAKLAVGDWIERVYNRRRRHSALAMMRPVEFEDRLIQTAQAA
>NZ_CP009483.1|WP_023369960.1|3742529_3743480_-|integrase
MSGHGLTSAFATELDAYLAFKAKMGFTGASRIWYLKRFDAYCAEHDRTVFDKDTVEGWVAVQLQHSGRYRSWMSYIRDVGRWMAMNEIPGAYVLSDRWKAPIVAAHPYLLSRREIELFFAAAARVQTPCPWRWQAAAFFTLMHSCGLRTGETRALQTGQVDLDAGHIDIIWSKGHRGRRLPLTAEVVEILDTCDRTSRDHFASRRTFFVSATGNQVSAATVGKIFGRIWDQAGLDRPVAGQQPRPYDLRHHFAYANIQRWMTAGDDVTAMLPYLSRYMGHATFDSTYYYVHTSPDFMAAYADITRDRQSLLPQVGF
>NZ_CP009483.1|WP_036448167.1|3741489_3742530_-|integrase
MRRDPHTGAPDFFGVARDYLHSYIPKTRGLSPKTVEAYRISLECFLDYLAEAEHIGREHLSFDRFDRPHLKGWLAWMTDQRHYTPKTVTLRLSAIKAFLAYAAYEDLTLVALSQAAKALKAPAGPRRPVEYLTEAQTRAILAAFTGQTAKSRRNRMLLILLYDTAARMGEITGLTLGDLRLTEPGHILLTGKGNKTRVVPLTDKTIGHLHVYLDEFHPNITKLPARRPLFYSLHRGRPAELSADTVAAVLKQAAESARTQCPSIPANIHCHLLRKTKAMDLYQQGIPLPIIMRLLGHENASTTAAFYAFATLDMMRQAINAATPAINTAATEPLTEDQLQTLYSLR
>NZ_CP009483.1|WP_080674250.1|3741066_3741213_-|hypothetical-protein
MWPTKAAAKLAVGDWIERVYNRRRRHSALAMMRPVEFEERLIQTAQAA
>NZ_CP009483.1|WP_036396191.1|3740535_3740850_-|DUF2563-domain-containing-protein
MFVDTDLLHSGGNQSHQAGGHAREGADQLAQGPLPSGTFGEFAAGETFHGVVSASLTKHVQTLQAHHEALSAIGDKAHHAAAGFTDMDERNAAKLRAVRCSSVT
>NZ_CP009483.1|WP_042313723.1|3751615_3753031_+|hypothetical-protein
MAPTAVRMVLVEGENGDGALVDQDQFDVSGDGDAATISAAQQVVSAILGTREGAYEGGYQLTSTGVTWRDPAQAAALREALANQKIEKVVLVSAFLAAAALAQAVGNETNYAHTALLFIEPETATLAVVDSADGSIADIQRQLLSDDDDTAVAQLTELVSAAESLETHPDAIFVVGSGIDIPMIKPALETATALPVTAAEEPDTALARGAALASANTPLFVSSTAALAYAQDPGTGALDPNRLDAAYFNDVSDSVQTGEGPLAYSAVPDSVVADSAVPDDQPERKPFPLLASIVTSIFVIGVAALALSLAVSIRSSTDVKPDPGHNVVTPSAPAPAAHAPAPKPQAPAPTPQAPTPQAPAPPEPAPAPQAPAPAPRAPAPAPQAPAPAPAPVPEAPAPAPAPAPVPAAPAPAPVPIPVPVQIPVPPIFGPGGGGGFPGGGDDGDDHGGGRGGGHGRGHGRGGFNIPFIPGL
>NZ_CP009483.1|WP_023369980.1|3753107_3754457_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MRCTVFGTGYLGATHAVGMAELGHEVLGVDIDPGKVAKLAGGDIPFYEPGLRKLLTDNLTAGRLQFTTDYDLAADFADVHFLGVGTPQKRGEYGADLRHVHSVIDALVPRLTRASVLIGKSTVPVGTAAELGRRAAALTPRNVTVEIAWNPEFLREGFAVRDTLHPDRIVLGVQDDSTRAEEAVRELYGPLLQAGVPFLVTDLQTAELVKVSANAFLATKISFINAISEVCESAGADVSLLADALGYDPRIGRQCLTAGLGFGGGCLPKDIRAFMARAGELGANQALTFLREVDSINMRRRSRMVELATIACGGSLLGANIAVLGAAFKPESDDVRDSPALNVAGQLQLNGAAVNVYDPKALDNAHRLFPTLNYAVSVAEACERADAVLVLTEWREFVDLDPDDLADRVRARVIVDGRNCLDVARWERSGWRVFRLGARAPVGDTQNRA
>NZ_CP009483.1|WP_023369982.1|3754594_3755272_+|ArsR-family-transcriptional-regulator
MAGQSNRKAALLEQISRVGKALGNGRRLQILDLLAQGERTVEAIATATGMNLTTASANLQALKSGGLVEARRDGTRQYYRLAGDDVARLFALVQVVADEHLADVAVAAAAVLGSPEDAITREELLRRQKSGEVTLVDVRPHEEYQAGHIPGAINIPVAELAGRLAELPADRDIVAYCRGAYCVMAPDAVHIARTAGRAAMRLDDGMLEWRLAGLPVHEGEAVRTP
>NZ_CP009483.1|WP_023369984.1|3755295_3756075_-|membrane-protein
MRRVLVVGYGAICYLIFVAAFLYAIGFVGNLLVPRTVDNGITASTSEAVVVNVVLLGLFAVQHSVMARPWFKSRWTRLVPATVERSTYVLLSSLLLFLLFWQWRTMPAVIWAVSWPPAKLLVLGLFWLGWIIVFTSTFMINHFDLFGLRQVYLAARARSYSHLEFRTTMLYRLVRHPIMLGFIVAFWATPTMTAGHLLFAVMTTGYILVALPLEEHDLSRALGDDYRRYRNRVPMLIPGLLLHRQRRTLHTGPAGTATK
>NZ_CP009483.1|WP_023369985.1|3756307_3756976_+|class-I-SAM-dependent-methyltransferase
MFSAGQSDLAVEQREHWQDTYRAHPAMYGPGPSLPAGYALEVFQAAGANRVLELAAGQGRDSLHFARAGLQVLATDFSDVAVAQLRRTAHSQRLGGRVRAIVHDLREPLPVEIGSFDAVFAHMALCMALSTKEIHAVVAEVRRALKPGGKFIYTVRHTRDEHYGMGQCHGDDIFECGGFAVHFFSRELVASLADDWVLEDVSAFAEGELPRRLWRVTVAKPT
>NZ_CP009483.1|WP_023369987.1|3757248_3758430_+|NAD(P)/FAD-dependent-oxidoreductase
MSKTIVILGAGVGGLTTADSLRQLLPPEDRIILVDRSFDGVLGLSLLWVLRGWRRPDEVRFRASPTSLPGVELVTATVGRIDVATRAVHTSNGVLGYDALVIALGATLDEAAVPGLAKALQAGVAGQFYTLDGAMELHTKVDALDRGRIAVLVAAVPFKCPAAPFEAAFLMAAQLGDRFASGAVRIDTFTPDPLPMPVAGPEVGQALVAMLEDRGIGFHGRKAVTAVDPADRTLHFGDGTTESFDLLAVVPPHVPSAAARSAGLGESGWIPVDPQALTTRVDGVWAIGDATVLTLPNAKPLPKAAVFAQSQAGVVAHGVARHLGYDVPERLFTGEGACYVETGDHQAAKGAGNFLRAPAPSVTLYPPSVAFHEEKVAQESAWLDRWNTRTSPP
>NZ_CP009483.1|WP_023369989.1|3758426_3759230_+|uridine-phosphorylase
MTDDQGRYPLVTPKAFDEPSVFRPANLLREARRQKSLPDKPVPAVCVLDPDGDVVRHLARAGTGYRHPGWACYHTEMWVVEVDGLEIGVVGMAVGAPFAVLVAEQLAVSGAALVVSITSAGRISGNETPPYFVLIERALRDEGTSAHYVAPGEWSYLAAGLKDKLRNAFGQNGIYVVTGSSWTTDAPYRETALAIKEAKRRGIACVEMEAAALYAYAAAAGRNVVCLAHITNTMAVDGDDFEKGSDNGVNVSLAVVSAVATAILGSP
>NZ_CP009483.1|WP_023369991.1|3759450_3759696_+|DUF4190-domain-containing-protein
MSSLAINGFAIAALAMSALGLLYVSIPLGIVALYQIARRRQQGREFAIAALVISAWWLSSLIAIAVAILLVWLTRPVRQPR
>NZ_CP009483.1|WP_036396187.1|3759784_3760540_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MDYTSAYLDQTREFGDLIRNADQSTPVPSCPGWNLGQLFRHVGRGDRWAAQIVRDRLDSFLDPRSVEEGKPPPDMDDAITWLRGGAQRLVDAVERTGTETPVWTFLGARPAGWWIRRRLHEVAVHRVDAAIAIGSEFTLEPDIAADGISEFLERIATQAGRDDADLPLQAGDTLHLHATDPGLGAAGEWTVGVDEGRITWSHEHGKGTVALRGSAAELLLAMVRRVPVADTGIEVFGDPAVWRKWLDGTPL
>NZ_CP009483.1|WP_023369995.1|3760551_3760926_+|nuclear-transport-factor-2-family-protein
MTTSEIATVLAWHDALNAGDVETLVSLSSDDIDIGDAHGAVQGHEALRRWAGSVMVAAELGQMYVHDGVVVVEQEITGRDDPGAVTTTASAFRVVRDHVTAVFRHDDLASALAATELTDDDLVD

Crispr_ID: NZ_CP009483_14

• CRISPR_ID: NZ_CP009483_14
• CRISPR_location: 3890540-3890647
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_14

Consensus_repeat	Method
TTGTGTGGCAGTGGTTTCCAGTGTGCAT	CRISPRCasFinder

spacers of NZ_CP009483_14

>14.1|3890568|52|NZ_CP009483|CRISPRCasFinder
TTATGGCGGTGTGACGTGTAGGGCGAGCATTTGCCGATGGAGTGCAGTTTGG

CRISPR arrays and Neighbor proteins around NZ_CP009483_14

CRISPR arrays

The CRISPR arrays of NZ_CP009483_14

>merge|NZ_CP009483|14|3890540-3890647|CRISPRCasFinder
TTGTGTGGCAGTGGTTTCCAGTGTGCATTTATGGCGGTGTGACGTGTAGGGCGAGCATTTGCCGATGGAGTGCAGTTTGGTTGTGTAGCAGTGGTTTCCAGTGTGCAT

>NZ_CP009483|14|14|3890540-3890647|CRISPRCasFinder
TTGTGTGGCAGTGGTTTCCAGTGTGCAT	TTATGGCGGTGTGACGTGTAGGGCGAGCATTTGCCGATGGAGTGCAGTTTGG
TTGTGTAGCAGTGGTTTCCAGTGTGCAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023370223.1|3897222_3898245_+|glycine-oxidase-ThiO	unknown	unknown	gnl|CDD|274092
NZ_CP009483.1|WP_023370231.1|3899975_3900497_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023370215.1|3893260_3894247_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NZ_CP009483.1|WP_036394680.1|3898440_3899196_+|thiazole-synthase	unknown	unknown	gnl|CDD|234687
NZ_CP009483.1|WP_080674251.1|3899234_3899972_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238861
NZ_CP009483.1|WP_036394677.1|3880835_3881519_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP009483.1|WP_023370201.1|3883657_3885748_+|phosphate-acetyltransferase	unknown	unknown	gnl|CDD|235537
NZ_CP009483.1|WP_023370197.1|3881649_3882414_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293807
NZ_CP009483.1|WP_023370203.1|3885737_3886910_+|acetate-kinase	unknown	unknown	gnl|CDD|234680
NZ_CP009483.1|WP_023370199.1|3882639_3883650_+|glucose-6-phosphate-dehydrogenase-(coenzyme-F420)	unknown	unknown	gnl|CDD|213827
NZ_CP009483.1|WP_023370205.1|3886871_3888053_-|DUF1501-domain-containing-protein	unknown	unknown	gnl|CDD|226587
NZ_CP009483.1|WP_023370213.1|3890876_3893261_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|319004
NZ_CP009483.1|WP_036394763.1|3896345_3897014_-|thiamine-phosphate-synthase	unknown	unknown	gnl|CDD|234590
NZ_CP009483.1|WP_023370189.1|3878286_3879402_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274646
NZ_CP009483.1|WP_023370191.1|3879398_3880733_+|FMNH2-utilizing-oxygenase	unknown	unknown	gnl|CDD|274819
NZ_CP009483.1|WP_023370209.1|3889576_3890434_+|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|380141
NZ_CP009483.1|WP_023370217.1|3894246_3895566_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023370207.1|3888049_3889360_-|DUF1800-domain-containing-protein	unknown	unknown	gnl|CDD|378055
NZ_CP009483.1|WP_023370219.1|3895750_3896374_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239217
NZ_CP009483.1|WP_023370225.1|3898241_3898439_+|thiamine-biosynthesis-protein-ThiS	unknown	unknown	gnl|CDD|135627

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023370223.1|3897222_3898245_+|glycine-oxidase-ThiO	gnl|CDD|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	3.19142e-105
NZ_CP009483.1|WP_023370215.1|3893260_3894247_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.79858e-106
NZ_CP009483.1|WP_080674251.1|3899234_3899972_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	2.89065e-46
NZ_CP009483.1|WP_036394677.1|3880835_3881519_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.53468e-18
NZ_CP009483.1|WP_023370201.1|3883657_3885748_+|phosphate-acetyltransferase	gnl|CDD|235537	PRK05632, PRK05632, phosphate acetyltransferase; Reviewed.	0
NZ_CP009483.1|WP_023370197.1|3881649_3882414_-|MBL-fold-metallo-hydrolase	gnl|CDD|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.15861e-48
NZ_CP009483.1|WP_023370203.1|3885737_3886910_+|acetate-kinase	gnl|CDD|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP009483.1|WP_023370199.1|3882639_3883650_+|glucose-6-phosphate-dehydrogenase-(coenzyme-F420)	gnl|CDD|213827	TIGR03554, F420_G6P_DH, glucose-6-phosphate dehydrogenase (coenzyme-F420). This family consists of the F420-dependent glucose-6-phosphate dehydrogenase of Mycobacterium and Nocardia. It shows homology to several other F420-dependent enzymes rather than to the NAD or NADP-dependent glucose-6-phosphate dehydrogenases. [Energy metabolism, Pentose phosphate pathway].	0
NZ_CP009483.1|WP_023370205.1|3886871_3888053_-|DUF1501-domain-containing-protein	gnl|CDD|226587	COG4102, COG4102, Uncharacterized protein conserved in bacteria [Function unknown].	1.43244e-45
NZ_CP009483.1|WP_023370213.1|3890876_3893261_-|serine/threonine-protein-kinase	gnl|CDD|319004	pfam16918, PknG_TPR, Protein kinase G tetratricopeptide repeat. This domain is found at the C-terminus of protein kinase G and contains a tetratricopeptide repeat (TPR).	0
NZ_CP009483.1|WP_036394763.1|3896345_3897014_-|thiamine-phosphate-synthase	gnl|CDD|234590	PRK00043, thiE, thiamine phosphate synthase.	7.94793e-81
NZ_CP009483.1|WP_023370189.1|3878286_3879402_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	5.76786e-107
NZ_CP009483.1|WP_023370191.1|3879398_3880733_+|FMNH2-utilizing-oxygenase	gnl|CDD|274819	TIGR03860, FMN_nitrolo, FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. This model represents a distinctive clade, in which all characterized members are FMN-binding, within the larger family of luciferase-like monooxygenases (LLM), among which there are both FMN- and F420-binding enzymes. A well-characterized member is nitrilotriacetate monooxygenase from Aminobacter aminovorans (Chelatobacter heintzii), where nitrilotriacetate is a chelating agent used in detergents. [Unknown function, Enzymes of unknown specificity].	2.36331e-161
NZ_CP009483.1|WP_023370209.1|3889576_3890434_+|DUF559-domain-containing-protein	gnl|CDD|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	2.62642e-07
NZ_CP009483.1|WP_036394680.1|3898440_3899196_+|thiazole-synthase	gnl|CDD|234687	PRK00208, thiG, thiazole synthase; Reviewed.	1.30704e-153
NZ_CP009483.1|WP_023370207.1|3888049_3889360_-|DUF1800-domain-containing-protein	gnl|CDD|378055	pfam08811, DUF1800, Protein of unknown function (DUF1800). This is a family of large bacterial proteins of unknown function.	4.08141e-108
NZ_CP009483.1|WP_023370219.1|3895750_3896374_+|NUDIX-hydrolase	gnl|CDD|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	4.48199e-15
NZ_CP009483.1|WP_023370225.1|3898241_3898439_+|thiamine-biosynthesis-protein-ThiS	gnl|CDD|135627	PRK05863, PRK05863, sulfur carrier protein ThiS; Provisional.	2.51372e-29

Protein sequences

>NZ_CP009483.1|WP_023370209.1|3889576_3890434_+|DUF559-domain-containing-protein
MWDSQAPFLGSEALACRALTRHQLRTHYRAVLPNVYLSRRAQVSLEQRIAAAWLWSRGSAVIAGAAAAALHGAKWIPDDFPVELICRNSRPPHGVLTRRDVLGDGEIQTVDGRAVTTPERTAFDIGRRGAVRSAVVRLDALARATGFKVDDVLCVAARHPGARGVRQLEIALELVDSGAQSPRESYLRLLLIDAGFPRPRSQIAVSGADGMPIAYLDLGWEDYMVAVEYDGDHHQRDRQQYVKDIRRIEMLEQLGWIVIRVVAEDRPADILRRVQAAMAERSSIV
>NZ_CP009483.1|WP_023370207.1|3888049_3889360_-|DUF1800-domain-containing-protein
MAGQSARWITTARVLRRAGFGASGREVDAVAGQDWPAHLDDILAADPDADPGARETPMPVLPTPRPRAKKATPAMREEFKRELAEQQAVLTGWWLRRMVAVRQPLREKLTLLWHNHFATSARKVRVPAYLAAQNQKLRTLALGDFRTLAYAMLTDAAMLRWLDGQSNTAKAANENLAREFMELFALGHGNGYTEDDVRAGARALTGWVIGTGGHTMMLPRRHDFTAKTLFGATGNFDAAGFCDAVLAQPKSAQHVAGRLWQQLAADEPPPPAVLDRLVSAYGPNRDLRALTRAVLTDEEFTGGRATVVTTPVEWLVGVIRSLRVPIDNHLKLIETTLKVLGQRPFFPPDVGGWPKGQVWLSTASAGTRLRTALHLANTADLSTVENTAAQDRIDAVGYLIGVGAWSDRSARALAPLVRRPPQLVAAAVNTPEYLTS
>NZ_CP009483.1|WP_023370205.1|3886871_3888053_-|DUF1501-domain-containing-protein
MINRRRFLIASAGAGAAGLLSGAVAVSWRDLQHAAHDRPLPDDAGVLVIVTLYGGNDGINTVIPYADNAYHDARPELAYTAGDVVQLDAQLGLNPGLRGLTQLWQQRQLAIVRGVGYPKPDHSHFRSMDIWQTASPAEPASTGWIGRWLDATGDDPLRAVNIGAVLPPLAVGEKHTAAALSTNPATQANDRFDATMQALSATDPDDTPAMAAVSRSYRDARTTDAAFASIKTDGSHNSLATQLNMVAAAVKGRVPARVYTVQLGGFDTHADERDTQQRLLQTFDEAVTGFLREMAGDRCGRNIVILAYSEFGRRVAANASQGTDHGTAGPVFVAGVPVNGGYYGDEPSLTDLDRGDLKSTTDFRDIYHELLVHTLATDPTPSVGTGRTSLGFL
>NZ_CP009483.1|WP_023370203.1|3885737_3886910_+|acetate-kinase
MTGSRLVLVLNSGSSSLKFQLIDPVSGMSRAAGNIERIGEASSSVRDHDAALRRAFDMLSEDGIDVATCGLMAVGHRVVHGGKDFHRPTVLDDAVVARLEELSVLAPLHNPPALLCIKVARTMLGDIPHVAVFDTAFFHDLPAAAATYAIDRELAEAWQIRRYGFHGTSHRNVSEQAAAFLGRPLETLNQIVLHLGNGASASAIAAGRPVDTSMGLTPLEGLVMGTRSGDVDPSIMWYLWRTANMGVDEIESMLNHRSGILGLAGERDFRRLHQLIEQGDLAARLAYDVFIHRLRKYIGAYLAVLGHTDALTFTAGIGEHDAAVRRDALAGLGELGLELDAGRNAAPAGGARQISTDDSPIAVLVIPTNEELAIARDCLQETQAGPAGSD
>NZ_CP009483.1|WP_023370201.1|3883657_3885748_+|phosphate-acetyltransferase
MSSSSPGTTAIYIAAPEPASGKATIALGILHRLTATVAKVGVFRPLTRASGARDYLLELLLEHTTAGLPYEQCVGVTYQYLHADTDTAITDIVAAYHAMAHKCDAVVIVGSDYTDVATPTELSVNARIAVNLGVPVLLAVNAKGRTADQVVSVVGVCLAELSAHHAHTAAVVANRCEPAELAAIREALRIVGPPSYALPEEPLLSAPTVAELERAVDGTAISGEAPLRNREVMDVLVAGMTADHVLERLGEGMAVITPGDRSDVVLAVASAHAAEGFPSLSCIVLNGGFDLHPSIAALVSGLRLRLPIIATTLGTYETASAAAAARGRLTATSQRKIDTALELMDRHVDTADLMTHLAIPIPTVTTPQMFTYGLQQRARSNRKHIVLPEGDDDRILKSAGRLLQRGIAELTILGDEARIRARAAELGVDLGQAKVLDPRTSPLCDHFAEQYAELRKSHGITAELAREIMCDVSYFGTMLVYNSHVDGMVSGAAHTTAHTVRPALEIIRTAPGISTVSSIFLMCLPDRVLAYGDCAIVPNPTPEQLADIAICSARTAAQFGIEPRVAMLSYSTGASGTGADVEKVREATELVRSREPQLLVEGPIQYDAAVDPAVAAAKMHDSPVAGRATVLIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLRKPVNDLSRGALIEDIVNTVAITAIQAQGIGDDR
>NZ_CP009483.1|WP_023370199.1|3882639_3883650_+|glucose-6-phosphate-dehydrogenase-(coenzyme-F420)
MAELKLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHKGGHAPFSLSWMTAVGERTKRVLLGTSVLTPTFRYNPAVIAQAFATMACLYPDRVFLGVGTGEALNEIATGYEGAWPDFKERFARLRESVRLMRELWRGDRVDFDGEYYRLKGASIYDVPEGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKGAELYTEKLIPGVLEGAAAANRNTDDIDKMIEIKISYDPDPELALQNTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQYVTWGLNHLVFHAPGHDQLRFLQLFETDLAPRLRRLG
>NZ_CP009483.1|WP_023370197.1|3881649_3882414_-|MBL-fold-metallo-hydrolase
MAHHLKTELVQVTDKVQLAHGQAVNWVLVTDDTGVMLIDAGYPGDREEVLASLRLLGYQPGDVRAILLTHAHIDHLGTAIWFAREHHTPVYCHADEVGHAKREYLEQVSLLDIALRIWRPRWAVWAAHVARSGGLVRDGIPTAQPLTAEVAAQLPGHPMAVFTPGHTNGHCSYLVDGVLASGDALITGHPLLRRDGPQLLPAIFSYSQQNCIRSLSALALLETEILAPGHGELWRGPIRGATDEALKRAGAFAR
>NZ_CP009483.1|WP_036394677.1|3880835_3881519_+|class-I-SAM-dependent-methyltransferase
MSSSTTVPGVSVVTQDGSAVEIYRRMPSLGEIEHIQSLLTPNSSVLELGAGTGRIADALAALGHRVTAVDDSPEMLAHIRRARAIQARIEDARLGEKFDAVLLVSNLINYPDAQLRRSMLATVAHHLRPGGQAIIEWVPPSMLASRQEGWTKTLTFDGAEAALTIHSNAGGIVTGEFTLTADGRRWHQSLVLQRVSPATVRDELTAAGLTLTTAAPNSTRWLLAKRR
>NZ_CP009483.1|WP_023370191.1|3879398_3880733_+|FMNH2-utilizing-oxygenase
MSRRPIHLAAHFPGVNNTTVWADPDAGSQIEFDSFVHLARTAERGLFDFFFLAEGLRLREHRGRIYDLDVVGRPDTFTVLAALAGVTDRIGLTGTINTTFNEPFEVARQFATLDHLSDGRAGWNIVTSSDAFTGANFRRGGFLDHGDRYARAEEFLTVARKFWDSWAPGAVLADVENGVYVDPGRIGSIEYSGTHFDVRGFATLPAGPQGHPVLLQAGDSAEGRAFAARHADAVFTLHASLQDAQRYYADMKGRARSYGRDPNRLKVFPAVTVVIGDTGTEAQDKARHIRRQQVSGATAIAMLEQVWGRDLSGYDPDGPLPDVEPIADSAVSQGRVRHVDTVALARRYRDKAAAENLSIRELVIAVTSRQQFVGTAAHIADEMDRYVQADACDGFILVPHLTPHGLDEFVDRVVPLLQARGAFRTEYAGATLREHLGLGPGARV
>NZ_CP009483.1|WP_023370189.1|3878286_3879402_+|LLM-class-flavin-dependent-oxidoreductase
MIPLSVLDLSPISAGSDAATALRNTVELAQQAERCGYRRFWIAEHHFVAVASAAPAVLIGQIAAATNRIRVGSAAVQLSHTTAAAVVESFGMLDAFYPGRIDLGLGRSAQRRGIKPRDPAKPRAPRPPVEWREVDGVVIPPPFDLRTLLASGRVQATMAILQQPEAVAPDFAEQVGDIIAMLAGTYRVDDFEVHAVPGEGAALTPWIFGSSKGRSAALAGAMGLPFVASYHLTPATALEAVDAYRAAFVPSVYLPQPYVVVSADVVVADDTATARHLAASYGHWVYSIRAGGGAIPYPDPADCAPLTEEQRAVVIDRLATQFVGNPDEVAQRLHALQRVTGADELVITSVTHRHQDRLRSHELIAHRWGLM
>NZ_CP009483.1|WP_023370213.1|3890876_3893261_-|serine/threonine-protein-kinase
MSPKPAHNDSAADDQEGRQDLAPGTQSADVQTGAAPGSRPLQSADVQTGAAPGSRPLQSADVQTGAAAGSRPPATQAIFRPDFDDDDDDLPISLGAMDTQPQERMSAATRALPPIRKLGGGLVEIPRVPDIDPLKALMTDPVVPESKRFCWNCGRPVGRSDAEGTGASEGWCPYCGSPYSFLPQLCAGDIIAGQYEVKGCIAHGGMGWVYLALDHNVNDRPVVLKGLVHSGDAEAQAIAMAERKFLAEVVHPSIVQIFNFVEHTDRQGDPVGYIVMEYIGGQSLRRGRGEKLPVAEAIAYILEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLNLPTRNGRYADGLPDDDPVLDKYDSFGRLLRRAIDPDPRRRFASTEEMSAQLTGVLREVVAADTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLDGQVHAEKLTAKEIVTALQVPLVDPTDVAAPVLQATVLSQPVQTLDSLRAARHGALDAEGVDLSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRWRLIWYKAVAELLTGDYDSAIKHFTEVLDTFPGELAPKLALGATAELAGYTDEHNFYQTVWQTNDGVISAAFGLARALSAKGDRAGAVRTLDEVPPSSRHFTTARLTSAVTLLSGRSQGEITEEQIRDAARRVESLPPTEPRVLQIRALVLGGAMDWLQDNQASTNHILGFPFTDHGLRLGVEAALRSLARIAPTQRHRYTLVDMANNVRPTSTF
>NZ_CP009483.1|WP_023370215.1|3893260_3894247_-|ABC-transporter-substrate-binding-protein
MKGLPSFSRAASPLALLAAAVLLAGCGHSESLKVETTPTLPYPTPVGMEVMPPEPPLPPDTASQDCNPTASLRPFRTKAEADAAVANIHERGRLIVGLDIGSNLFSFRDPITGDITGFDVDIAGEVARDIFGSPSHVEYRILSAAERITALQTSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILAPRDSSISKVSDLSGKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVAMQQRQIDAVSTDDSILAGLVEEDPYLHIVGPDMANQPYGIGINLDNTGLVRFVNGTLERIRTDGTWNTLYRKWLSVLGPAPVPPQPRYLD
>NZ_CP009483.1|WP_023370217.1|3894246_3895566_-|hypothetical-protein
MTVELAHPSTEPLGLRSPAEPAHPRWWFVSTTPGRILTIGIVLAALGVSSAFATSTTINHRQQVLTTVLEHTEPLSFAAGRLYTTLSVADAAAATAFIAQAEPRAVRLRYEQAITDAAVAVTRASSGLTDESLVQLLGRINAELAVYTGLIEIARTNNRAGNPVGSSYLSEASGLMQTTILPDAQQLYQATSERVDTETTASTQIPAPVILVVTTTVVFGAFSHRWLARRTRRRINPGLIVGALGILVMVVWVGTALTISTAASRSAKDTAAESLKTVTNLAITAQQARADETLSLIRRGDEEIRKQSFYQRIEAMHHQLDDYMARRDAVDKPDLQGADQLLVRWQQANDRINSYISVGNYRAAIQVALGKGEDDATPAFDKLDEALTKAMEQSRNRLRNDVLNARRGLAGAQVGGVVLSVGAAIAVALGLWPRLKEYR
>NZ_CP009483.1|WP_023370219.1|3895750_3896374_+|NUDIX-hydrolase
MQGDGDGWVVSDDGAHYWGRFGSAGLLLRAPLPDGGPAVLLQHRAVWSHQGGTWGLPGGARDSHETPEQTAVREAREEAGLAAQRLVVRSVLVTARPRGTAWTYTTVVADTDELLHTVPNRESAELRWVAEDDVTDLPLHPGFAASWQLLRTAPVTVPLHRGDERRRRLPCTVVIEDGVFVWCMPGDADLAPSQLSPRVSSLLEALT
>NZ_CP009483.1|WP_036394763.1|3896345_3897014_-|thiamine-phosphate-synthase
MARLARLAEARLYLCTDARRERGDLAEFADAALAGGVDIIQLRDKGSAAEQRLGPLEALDELAACEILVDAARRHGALFAVNDRADIAAAAGADVLHLGQRDLPSSIAREIVGPGVLIGRSTHDRDQVAAAAVGDADYFCAGPCWPTPTKPGRPAPGLDLVRAAAAIGGDKPWFAIGGIDAPRLPEVIAAGARRIVVVRAITAADDPKAAAQQLRSALPAAS
>NZ_CP009483.1|WP_023370223.1|3897222_3898245_+|glycine-oxidase-ThiO
MSAPTPAGSLAVIGGGVIGLSVARRAARAGWSVRVHRGGEHGASWVAGGMIAPHSEGWPGEERLLRLGLESLRLWHDGGFLDGLPSHVVTARESLVVAVDRADVADLRTVADWLSQQGHPVVWESAARDVEPLLAQGIRHGFRAPTELAVDNRALLDALTVDCERLGVAWAAPVTGLSDAEGDVVVIANGIDAPALWPGLPVRPVKGEVLRLRWRKGCMPLPRRVIRARVHGRQVYLVPRADGVVVGATQYEHGRDTAPVVSGVRDLLDDACAVLPVLGEYELAECSAGLRPMTPDNLPIVQRLDARTLVAAGHGRSGFLLAPWTAEQIMCELAAVGASA
>NZ_CP009483.1|WP_023370225.1|3898241_3898439_+|thiamine-biosynthesis-protein-ThiS
MIVVVNEQQVEVDEQTTVAALLQSLGFPDRGVAVALDCALLPRSDWATMLSEGDRLEVVTAVQGG
>NZ_CP009483.1|WP_036394680.1|3898440_3899196_+|thiazole-synthase
MGDKLTIGDRSFASRLIMGTGGASNLAVLQEALVASGTELTTVAIRRVDAEGGTGLLDLLNRLGITPLPNTAGCRSAAEAVLTAQLAREALDTNWVKLEVIADERTLLPDAIELVRAAEQLVDDGFVVLPYTNDDPVLARRLEDAGCAAVMPLGSPIGTGLGITNPHNIEMIVAQAGVPVVLDAGIGTASDAALAMELGCDAVLLATAVTRAADPPAMAAAMAAAVTAGHLARRAGRIPKRFWAQASSPEL
>NZ_CP009483.1|WP_080674251.1|3899234_3899972_+|SGNH/GDSL-hydrolase-family-protein
MAAGPGIRPRADGAPWRSGRSARNYPHLVAEQQRLKLVDVTYSGATTANVLGDHQHGAPPQITALDGSESLVTVTIGGNDVGYIPLLMAAALPRPARRLPLLGAWIAELLDRNSRDQALAQVFDSLCEVGRSLRRRAPRSRVLFVDYLTLLPPAGVPAPPLSAAHSELGRHVAATLERLTADAAALTGCEVVRAAAASRDHHAWSPEPWTEKPARFGVPLPARPAPLHPNAAGMRAVAKLVAAQL
>NZ_CP009483.1|WP_023370231.1|3899975_3900497_-|hypothetical-protein
MSHFTTALRAATAAALMASLACLGTATANADPTGTASDVNTLAGSVSKGYGLNNCAAQTITSGELAALSCGQNPDAAGPALAKYILFATPDDMNGSFKASIKDETLTACGDSGQSPTTWRQGSAGATAGQVACGTYQGAAEIIWTTDAKNVLSYIRAGNSDVPALYQWWRTNG

Crispr_ID: NZ_CP009483_15

• CRISPR_ID: NZ_CP009483_15
• CRISPR_location: 4461139-4461237
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_15

Consensus_repeat	Method
CTGCGCGGCGCCGACCTGAGCGGC	CRISPRCasFinder

spacers of NZ_CP009483_15

>15.1|4461163|51|NZ_CP009483|CRISPRCasFinder
GCCGACCTGAGCGGCTGCCGGCTGCGCGAGACCAGCCTGGTGGAGGCCGAC

CRISPR arrays and Neighbor proteins around NZ_CP009483_15

CRISPR arrays

The CRISPR arrays of NZ_CP009483_15

>merge|NZ_CP009483|15|4461139-4461237|CRISPRCasFinder
CTGGCGGGTAACGACCTGCGCGGCGCCGACCTGAGCGGCTGCCGGCTGCGCGAGACCAGCCTGGTGGAGGCCGACCTGCGCAAGGCCGTGCTGCGCGGG

>NZ_CP009483|15|15|4461139-4461237|CRISPRCasFinder
CTGGCGGGTAACGACCTGCGCGGC	GCCGACCTGAGCGGCTGCCGGCTGCGCGAGACCAGCCTGGTGGAGGCCGAC
CTGCGCAAGGCCGTGCTGCGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023371260.1|4459902_4460286_+|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NZ_CP009483.1|WP_023371282.1|4474442_4474736_+|DUF3017-domain-containing-protein	unknown	unknown	gnl|CDD|378602
NZ_CP009483.1|WP_036391037.1|4475360_4476803_+|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354
NZ_CP009483.1|WP_023371280.1|4473588_4474446_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	unknown	unknown	gnl|CDD|237637
NZ_CP009483.1|WP_023371284.1|4474760_4475153_-|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NZ_CP009483.1|WP_036391603.1|4447908_4451211_+|error-prone-DNA-polymerase	unknown	unknown	gnl|CDD|235553
NZ_CP009483.1|WP_023371278.1|4472364_4473549_-|NADH:flavin-oxidoreductase	unknown	unknown	gnl|CDD|239201
NZ_CP009483.1|WP_023371276.1|4470861_4472316_+|hypothetical-protein	unknown	unknown	gnl|CDD|226013
NZ_CP009483.1|WP_023371270.1|4466468_4469105_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP009483.1|WP_023371254.1|4455590_4456343_-|response-regulator-receiver	unknown	unknown	gnl|CDD|377145
NZ_CP009483.1|WP_036391606.1|4454546_4455563_+|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197666
NZ_CP009483.1|WP_023371250.1|4453865_4454330_-|tRNA-(cytidine(34)-2'-O)-methyltransferase	unknown	unknown	gnl|CDD|223297
NZ_CP009483.1|WP_023371262.1|4460266_4460857_+|ATP-binding-protein	unknown	unknown	gnl|CDD|225138
NZ_CP009483.1|WP_023371258.1|4459495_4459927_+|hypothetical-protein	unknown	unknown	gnl|CDD|224929
NZ_CP009483.1|WP_042312730.1|4451941_4453723_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NZ_CP009483.1|WP_023371246.1|4451296_4451941_+|nitroreductase	unknown	unknown	gnl|CDD|380311
NZ_CP009483.1|WP_042312735.1|4461412_4463920_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP009483.1|WP_036391034.1|4463978_4466441_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP009483.1|WP_023371274.1|4469614_4470865_+|hypothetical-protein	unknown	unknown	gnl|CDD|273224
NZ_CP009483.1|WP_036391609.1|4456796_4459499_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|340391

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023371260.1|4459902_4460286_+|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	7.98889e-29
NZ_CP009483.1|WP_023371282.1|4474442_4474736_+|DUF3017-domain-containing-protein	gnl|CDD|378602	pfam11222, DUF3017, Protein of unknown function (DUF3017). This bacterial family of proteins with unknown function appear to be restricted to Actinobacteria.	1.51988e-13
NZ_CP009483.1|WP_036391037.1|4475360_4476803_+|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	5.60764e-41
NZ_CP009483.1|WP_023371280.1|4473588_4474446_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase	gnl|CDD|237637	PRK14193, PRK14193, bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional.	0
NZ_CP009483.1|WP_023371284.1|4474760_4475153_-|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	3.33542e-22
NZ_CP009483.1|WP_036391603.1|4447908_4451211_+|error-prone-DNA-polymerase	gnl|CDD|235553	PRK05672, dnaE2, error-prone DNA polymerase; Validated.	0
NZ_CP009483.1|WP_023371278.1|4472364_4473549_-|NADH:flavin-oxidoreductase	gnl|CDD|239201	cd02803, OYE_like_FMN_family, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	5.82555e-112
NZ_CP009483.1|WP_023371276.1|4470861_4472316_+|hypothetical-protein	gnl|CDD|226013	COG3482, COG3482, Uncharacterized conserved protein [Function unknown].	4.67156e-70
NZ_CP009483.1|WP_023371270.1|4466468_4469105_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.38035e-67
NZ_CP009483.1|WP_023371254.1|4455590_4456343_-|response-regulator-receiver	gnl|CDD|377145	pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.	5.77195e-16
NZ_CP009483.1|WP_036391606.1|4454546_4455563_+|AraC-family-transcriptional-regulator	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	5.45565e-20
NZ_CP009483.1|WP_023371250.1|4453865_4454330_-|tRNA-(cytidine(34)-2'-O)-methyltransferase	gnl|CDD|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	3.32414e-77
NZ_CP009483.1|WP_023371262.1|4460266_4460857_+|ATP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	2.63673e-62
NZ_CP009483.1|WP_023371258.1|4459495_4459927_+|hypothetical-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	1.19979e-31
NZ_CP009483.1|WP_042312730.1|4451941_4453723_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.03789e-30
NZ_CP009483.1|WP_023371246.1|4451296_4451941_+|nitroreductase	gnl|CDD|380311	cd02062, Nitro_FMN_reductase, nitroreductase family protein. Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.	4.04745e-27
NZ_CP009483.1|WP_042312735.1|4461412_4463920_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.68978e-66
NZ_CP009483.1|WP_036391034.1|4463978_4466441_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.38103e-66
NZ_CP009483.1|WP_023371274.1|4469614_4470865_+|hypothetical-protein	gnl|CDD|273224	TIGR00702, Uncharacterized_protein_Rv1375/MT1419, YcaO-type kinase domain. This protein family includes YcaO and homologs that can phosphorylate a peptide amide backbone (rather than side chains), as during heterocycle-forming modifications during maturation of the TOMM class (Thiazole/Oxazole-Modified Microcins) of bacteriocins. However, YcaO domain proteins also occur in contexts that do not suggest peptide modification. [Hypothetical proteins, Conserved].	1.94166e-123
NZ_CP009483.1|WP_036391609.1|4456796_4459499_+|HAMP-domain-containing-protein	gnl|CDD|340391	cd00075, HATPase, Histidine kinase-like ATPase domain. This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.	9.66888e-17

Protein sequences

>NZ_CP009483.1|WP_023371262.1|4460266_4460857_+|ATP-binding-protein
MASKHSEAHLRDTAAHASTKIVIAGGFGAGKTTFVGAVSEIMPLRTEAMVTDASVGVDMLEVTPQKQTTTVAMDFGRITLGEDLVLYLFGTPGQRRFWFMWDDLVRGAIGAIVLVDCRRLEDSFAAVDFFEHRNLPFLVAVNEFDGAPRYPAAEVRQALTLPAHIPVINIDARSRRSATDALIAVSEYALASLTGS
>NZ_CP009483.1|WP_023371260.1|4459902_4460286_+|DUF742-domain-containing-protein
MDRREPPLARPGANLVRPYTLTAGRTGTDIDLPLEAAVQALPAGSAHRWPPHDMRGRIIRLCADSPSSPSVAEIAARLDLPVGVARVLVGDLVSSDYLRVQATLTDRSTSDERRELIGRTLRGLQAL
>NZ_CP009483.1|WP_023371258.1|4459495_4459927_+|hypothetical-protein
MNTRSLDSPLDWLVSKFAREVPGVAHALLVSVDGLPLAASEYLPRERADQLAAVASGLASLATGAAQLFEGGQVLQSVVEMQNGFLLLMRVGDGSHLATLAVTGCDIGQIGYEMAILVERVGSVVQSSRRAQPEPQWTDASRR
>NZ_CP009483.1|WP_036391609.1|4456796_4459499_+|HAMP-domain-containing-protein
MFARPTTPVAAVPPEVRGAQRRPARHRPAAWSLSNWPVGWKVVAIAVVPLLLATVFGVLRIDAAMANSGNLRLVAARANVIPAITKYMSALDVALLASSTGRDVEGAKKNFTARKYELQTRLADTDVIPDVRSGVNTLLNGGQALLDKVLENSIGLRDRITTYAPLLLTAEDAINASVRVDSEQIRAQVQGLSRAVGARGQMTMQEILVTRGADLPEPQLRTSMITLAGTEPSTLFGMSEVLGVGSPDAKNLQQQLLTRMAIMSDPASELVDNPELLRSIKVTDGIAEQVIKGATASVTNSVQAQATARRDAAVRDAVLVLAAIAIALVVVLLVARALVRPLRVLRDGALKVAHTDLEGEIARVRAGAEPQPQPLAVYTTEEIGQVAHAVDELHTQALLLAGDEARLRLLVNDMFETMSRRSRSLVDQQLSLIDRLERNEQDPDRLDSLFRLDHLAARLRRNSANLLVLAGAEISRERREPVPLPTVVSAAVSEVEDYRRVAVGGVADCKVIGGAAGSVIHLLAELIDNALSYSPPTTTVRVSAVRGSAGGVLLRVADCGLGMTDSDRRIANMRLQSGGEVTPDNARHMGLFVVGRLAARHGIRVGLRGPSTGEAGNGTTAEVYLPVAVLAGGESPASQAGAPAPTPRPFIIKPPTPEPAADPAATSSYQNGADKPVPPVTLLPRRKPGSSGITDIPAPPAGQQPRARRELKTPWWETRHDARHDAQRDAQQTPAQTPPTKQATASDTSAFFAQRSTAAAARPADPPPKPSVPAGPVDDDVIYQRMLSEMMGDPRELAASPDLDWRSVWDRGWSAAAQAQDKPVESRTDHGLPVRTPGARLVPGAAEPEPGVGPHPDRQPPAAAAVRDPDAVRASIGSHFGGVHTGRAHARTTSQEADQQ
>NZ_CP009483.1|WP_023371254.1|4455590_4456343_-|response-regulator-receiver
MRCGEGADSRPGDDSRRPETGLSPERQHMYTVLSEVDELQRRGETDFESALRDINAITVASVPGAQYLGVTVVDTSGTIETLAATHRYPALLDDVQRDVREGPCLSAAWEQHTIRIDDLTTDGRWPRYRTAALDRTPVRSIMSFRLFGSDKALAALNFYADSTRAFDDESVELGLVFAAHTTVVWNLIRRQQQFRSALASRDLIGQAKGILMERFDINAVAAFELLRRLSQESNTKIVEIAEKLIELKRR
>NZ_CP009483.1|WP_036391606.1|4454546_4455563_+|AraC-family-transcriptional-regulator
MSTGPAARSRPRPREPARESAPRELDFDSSDLAETEDFLVRTYTKMRISGEGRMCRARIQRRCLGSLSIDELSFSYDMGYDANPLGKILLCRVRRGRIEENFIGEPQHVLAAGELAMIGPPELPHSGRVRHAGYQLIGFDPALLDRVAPNAPDRAHEPVRLTGHRPVSVAAGNRLTALIDYLRDHILADPSAASAPLVIDTAAAHLAVATLNAFPHSALLDPTPTDRRDSAQPVLLRRAMAFIEENAHQDIALADIAAHVYVTPRALQYMFRQRLDCTPMQYLRRVRLDRAHRELLDSSRASATVKQIANRWGFIHIGRFAIYYRETYGRSPHATLRG
>NZ_CP009483.1|WP_023371250.1|4453865_4454330_-|tRNA-(cytidine(34)-2'-O)-methyltransferase
MFKLMFVSPCIAPNTGNAIRTAAATGCELHLVEPLGFDLSEPKLRRAGLDYHDLASVTVHASLTAAWDALLPARVFAFTAQATTPFSDVSYRAGDVLMFGPEPTGLDAATLADAHITEQVRIPMLAGRRSLNLSNAAAVAVYEAWRQHDYSGAL
>NZ_CP009483.1|WP_042312730.1|4451941_4453723_-|PE-family-protein
MSYLVAVPEAVSAAATKVAEFGAALRSANSSAAGATTGLLAAGGDEVSAAIASLFSTHGQAYQEVAAQMTAFHDRFVQALTAGAGAYAHAEAANASPLQTLEQDVFGAINAPTQALLGRPLIGDGAAGTATNPNGQDGGLLFGNGGAGYSQPAGSGLAGGNGGSAGLIGNGGIGGAGGAGAAGGAGGHGGWLTGNGGNGGVGGNAVLAGGSGGNGGAGGAAGLWGDGGTGGHGGAGLAGNNGVNPTPVTDPGLNGKPGDSNVPGPNGFETGTKGGDGTTGGAGINGGNGGDGGAANANFTTSFGAVGGAGGNGATGGYGGATGGAGGSGGPAASEFGPALGGNGGNGGDGGAGTNGQAGGAGGVGGAGGNGGWLVGNGGAGGAGGNGAIGGNGDIGGTGGAGGFNGVPGGNGAASTFAVASGGAGGNGGSGGTGGHGGHGGSGGTGGAGGAAGWLAGNGGSGGQGGSGGAGGVGGAGGTGIDGAPGATAFSEHYVTDGGDGGAGGNAGHGGTGGDGGDGGHGGAGGRGGLLSGQLGAAGIGGGGGIGGGGGTHGTPGNGGAGALGTDVSGFDGKAGLGGDAFNGVNGSNGKPG
>NZ_CP009483.1|WP_023371246.1|4451296_4451941_+|nitroreductase
MALNLTVDEVLTTTRSVRKRLDFDQPVPRDVLMECLELALQAPTGSNSQGWQWVFVEDAATKKAIADVYLTNARAYLSAPAPEYPEGDTRGERMGKVRNSATYLAEHMHEAPVLMIPCIQGREDQTPLGGVSFWASLFPAVWSFCLALRSRGLGSCWTTLHLLGDGERQVADLLGIPYDQYSQGGLFPIAYTKGTDFRPAKRLPTESLTHWNSW
>NZ_CP009483.1|WP_036391603.1|4447908_4451211_+|error-prone-DNA-polymerase
MGWGNGPPSWAEMERVLDGKPRHAGAPVAAEPADDAGLEGPWSRQRGTYQPPENARVRSSAAYAELHAHTAYSFLDGASTPEELVEEAARLDLCALALTDHNGLYGAVRFAEAAAELDMRTVFGAELSLGSEARTEQPDPPGPHLLVLARGPEGYRRLSRQLAAAHLAGGEKGKPRYDFDALTEAAGGHWHILTGCRKGHVRQALSEGGPDAAQRALADLVDRFGAYRVSIELTHHGHPLDDERNATLAGLAPRFGVGVVATTGAHFAHPSRSRLAMAMGAIRARQSLDSAAGWLAPLGGSHLRSGDEMARMFAWRPEAVTAAAELGGQCAFELALIAPQLPPFDVPGGHTEDSWLRQLVMAGARHRYGPPDGAPRAYAQIGHELKVIAQLKFPGYFLVVHDITQFCRRNNILCQGRGSAANSAVCYALGITAVDPVANELLFERFLSPARDGPPDIDIDIESDRREKVIQYVYDKYGRDYAAQVANVITYRGRSAVRDMARALGFSQGQQDAWSKQISHWNGQAAEVDGIPEQVVDLATQIRNLPRHMGIHSGGMVICDRPIADVCPVEWARMENRSVLQWDKDDCAAIGLVKFDLLGLGMLSALHYAMDLVAEHKGLEVDLAKLDLSEPAVYEMLARADSVGVFQVESRAQMATLPRLRPRVFYDLVVEVALIRPGPIQGGSVHPYIRRRNGIDPVVYEHPSMAPALRKTLGVPLFQEQLMQLAVDCAGFTAAEADQLRRAMGSKRSTERMQRLRGRFYDGMRALHGTRDEVIDRIYEKLEAFANFGFPESHALSFASLVFYSAWFKLHHPAAFCAALLRAQPMGFYSPQSLVADARRHGVVVHGPDVNASLAHATLENAGMEVRLGLGAVRHIGDDLAEKLVGERNANGPFASLLDLASRVQLSVPQTEALATAGALGCFGMSRREALWAAGAAATQRPDRLPGVGAQGADGSHIPVLPGMSELELAAADVWATGISPDSYPTQFLRADLDAMGVLPADALGSVPDGDRVLIAGAVTHRQRPGTAQGVTFINLEDETGMVNVLCTPGVWARHRKLANTAPALLIRGQVQNASGAITVVAERLGRISLAVGSRSRDFR
>NZ_CP009483.1|WP_042312735.1|4461412_4463920_-|ABC-transporter-ATP-binding-protein
MNTVAPPVLTVLGLGPQRTFAAGHDIIVGSDLRADMHVSHPSVSRAHLLLRFDHGRWMAIDNGSHEGTFVDHRRVHAVEIHPGQRINIGSPDGPCLTFEVGQPEVPAGRPPRTAPIPAAQLRPHPAARPVPPPAPGPMPAMEPAHPAPPTRLGRLGPYLAPDPAPPRPPSHPPVPPRDPSNLATKVIRSLWPESGRNRRLAGAVTVGRAQDNDIVVPDVLASRRHAFLVQTALGTEIRDARSVNGTYVNGVRIGSAVLSEGDVVTIGNVDMVFSAGTLTRQADAGTPAGGLEVNRVQFEIDGKQLLDNISLTARPGTLTAIIGGSGAGKTTLARLIAGYTRPSAGSITFEGHDIHAEYATLRSRIGMVPQDDVVHRQLTVNQALGYAAELRLPPDTSSADRAKVVARVLEELELTEHGDTRVDKLSGGQRKRASVALELLTGPSLLILDEPTTGLDPALDSQVMMMLRKLADAGRTVVVVTHSVSYLDLCDQLLLLAPGGKTAYFGPPDQVGSVMGTSNWAHIFIKVGADPDEAKRRFLAQRGSEPKLSARAEPGDLGEPVHVDVWRQFSTVARRQVRLVVSDRWYTVFLAALPFMLGLLTLTVPGHSGFGVADPNGKTPAEPAQILVLLCVGAVFMGTALTIRDLVGERPIFHREQAFGLSTQAYLLAKIAVFSMFATAQAAIVTTIAVIGKGAPTRGAVLLGNPTLELFVAVAATCFASAIVGMGMSALARSSDQILPLLVVAIMAQLVFSSGIIPVTNRVVLDQLSWLTPARWGFAASASTIDLNTVQPSPFSPKDSHWHHTTGAWLLDMAMLGLLSTVYAGFVLWRIRLKR
>NZ_CP009483.1|WP_036391034.1|4463978_4466441_-|ABC-transporter-ATP-binding-protein
MTRAQRPVLTVRSDRSQRSFAPGADAIVGSDLRADLRVAHPLVAQAHVVVRFEQGNWIAIDNSRTGMFVDGRRVPLVDIRDGLVVNLGRPDGPRISFEVGHHRGIIGLLPQTGFPPPGGPAAGTEQQQHRPPAQPPGPAPPAPGAPGYPGAQRTTVIPVSPPPPQAERTTTLNVAGAASGHAPTGAGISWIGRALDNDIVVADVLASRHHAFLTPTPVGTEINDAHSINGTFVNGIRVGSAILREGDVVTIGNVDLAFTGTTLVRRAEAATRTGGLEVTGISYTVNGAALLDNVSLTARPGTLTAVIGGSGAGKTTLSRLIAGYLSPTSGTVTFEGHNIHTEYASLRSRIGMVPQDDVVHRQLTINQALGYAAELRLPPDTSKQDRAQVVAGVLEELRLTEHADTRVDKLSGGQRKRASVALELLTGPSLLILDEPTSGLDPALDLQVMTMLRQLADAGRVVLVVTHSLTYLDVCDQVLLMAPGGKTAFLGPPDQIGQAMGTTNWAQIFAKVGADPDEANRRFLARNQPPAPAPIETPTDLGEPAHTSVRRQFSTIARRQVRLVVADRAYFTFLAALPFVLGALSLTVPGDTGFGMAQPTSQTPDEAAQILTLLSIAAVFMGTALTIRDLIGERAIFRREQAVGLSTRAYLGAKITVFCMFAITQAAITTGVVLLGKGVPTQQAVLLGNPSFELFTTVAATCVASAILGLLLSSVARSSEQIMPLLVVSLMLQLVLAGGLVPVTNRLFLDQLSWAVPARWGYAASAATVNLRELVPGSYSPEDSHWTHSRPAWLFDMAMLATLSVAYACLVWWRIRLRRH
>NZ_CP009483.1|WP_023371270.1|4466468_4469105_-|ABC-transporter-ATP-binding-protein
MPQSAPPALTVRYDGSARTFAPGHDVVVGRDLRADMRITHPLISRAHLLLRFDQGRWLAIDNNSLNGTFCNGRRVPMVDIQDGQSVNIGNPDGPLLTFEVGRHVGMAGRPPQTESMRVGTQSSPWPPAATQVAGHPGPPPPARQSNWTAPPSARPHPGPPPKSGQPMYPSSASRQPGFAPGPPRQPSNQPPNQPPNYAPAGPRPSPPTQMQPSAAKPPEVANLATKMIHALLPRTGSNEMPAGSVTIGRATDNDVVIQDVLASRHHAFLTMTPLGTEIRDAHSVNGTFVNGVRVGSAILSDGDVVTIGNVDLVFTGGTLIRRTEAATRTGGLEVKSVCFKADGKQLLDHISLTARPGTLTAIIGGSGAGKTTLSRLIAGYTSPSSGTVTFEGHNIHTEYASMRSRIGMVPQDDVVHRQLTVNQALGYAAELRLPPDTSKADRDQVVAQVLEELELTKHADTRVDKLSGGQRKRASVALELLTGPSLLILDEPTTGLDPALDRQVMMMLRQLADAGRVVLVVTHSVSYLDVCDQLLLVAPGGKTAFLGPPDQIGQAMGTTNWADIFAKVGADPDEANRRFLADKQAQPAFPSQASPAADLGEPVHTDVFRQFSTIARRQVRLVVSDRGYTVFLALLPFLIGVLSLTVRGKTGFGMSDPLGNNPAQPDQILVMLNVGAVFMGTALTIRDLIGERPIFRREQAVGLSTAAYMAAKIVVFSAFAIAQAAIATTICVIGWGKPLSDAVLLGDVRFELFVTVAATCVASAMLGMALSALAQSQDQIMPMLVFSIMSQLVFSGGMIWVTDRILLDQLSWATPARWGYAASASTIDTHRLVPGPTDPKDQHWDHKASAWLFDMAMLGVVSIAYTAIVWWRIRLRRR
>NZ_CP009483.1|WP_023371274.1|4469614_4470865_+|hypothetical-protein
MSESCAAATAASVGPDWSQWPTRVLGHANPTSIAHRAGTYRIMSPEQTWRAVQPMLELAGITRVADLTWLDDLGIPTVQAVRPASVTLSVSQGKAATYRAAQVSAVMESLETWHAENVTPDLFSMRTTDLAAALTYDPAHLLLSARSIYHPGAKLDWMTATTLLTGRQTWVPWEAVLVNAAVDNRWDPPMFSMDTTGLASGNSYWEASLHGLYEVMERHAMAAGEPGSTLFEVPVDDVADSGCAELVDMIYRAGSELKIARTDTWDGFPCFTAEICSPMLGVPFSGFGLHHDPNVALSRAITEAAQSRLTAISGAREDLSPALYHRFARVHAYGPLRPTMRHLPTAEPTPWHVPGTDSLSDLLASAATAVADRSGTEPLAVVCDLAGSCVPVVKVIAPGLTASHGSPMRTPLQESA
>NZ_CP009483.1|WP_023371276.1|4470861_4472316_+|hypothetical-protein
MRAARRIVVTAGPTIGVADVHTVVPNAEVVPPISFGDALRYGLKPGDTLLIVDGLFFQHPPVRHKELLTLIQDGVRVVGSSSMGALRAAELHPFGMEGYGWVFDNYRNGYLEADDEVAMVHGEPEDGYPVFVDALVNIRQTLARAVETGLLSAQLAADLVETAGRTPFTMRTWDRLLAALEVPERSCLAKQLTASRVDIKHADAVVALRNIVDGQDGVATRPGPPPTVWSVRWKQRWEPPVPVAITSGTDTDTGTTLGVRDTDVLSLLSICAADRWAYLPALEQVASWYWIVTHPGDHGDVRQHASRAVAQVAAGTRRRALETVAHRYAVAIGLADESGFPASVRSQWLTDEENATLGTDPIAVSALLVTRTLFVTRSLPAIEHFLDLLRADPRLPHWRSVTAQALARRDELARRKPHLNLHRPDPRQLKNLFAKRWGAEVDRIELARRGLMSEEAFYTAATLFAVAAADDRLPSIEVGALGPA
>NZ_CP009483.1|WP_023371278.1|4472364_4473549_-|NADH:flavin-oxidoreductase
MPDAPDVLGPAKLGPLTLRNRVIKAATFEARTPDALVTDDLIEYHRLPAAGGVGMTTVAYCAVSPGGRTSGDGMWMRPEAVPGLRRLTDAVHAEGAAVSAQIGHAGPVADARSNKATALAPVRFFNPIAMRFAKKATRDDIADVTAAHANAARLAVDAGFDAVEIHLGHNYLASSFLSPLINRRDDEFGGSLENRAKVARGLVLAVRHAVQQQIAVTAKLNMADGIRGGITTEEALTTAKWLQDDGGLDALELTAGSSLVNPMYLFRGDAPVKEFAGAFKPPLRWGIRMTGHKFLREYPYRDAYLLRDARLFRAELSMPLILLGGITNRETMDLAMAEGFDFVAMARALLAEPDLVNRIAAEGQRARSACTHCNLCMPTIYSRTRCVVTGAPDR
>NZ_CP009483.1|WP_023371280.1|4473588_4474446_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase
MGAIMLDGKATRDEIFVDLKRRVAALTSSGSASGRPPGLGTILVGDDPGSHAYVRGKHADCAKVGITSIRRDLPADISTATLNETIDELNANSDCTGYIVQLPLPKHLDENAALERVDPGKDADGLHPTNLGRLVLNTPAPLPCTPRGIVHLLRRYDVELAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLAALTRQADIIVAAVGVPHMLTADMVRPGAAVVDVGVSRTDDGLVGDVHPDVWEVAGHVSPNPGGVGPLTRAFLLTNVVELAEQR
>NZ_CP009483.1|WP_023371282.1|4474442_4474736_+|DUF3017-domain-containing-protein
MTARAILAHTFRAQWPILLVGLIFTVAFVLVGANFWRRGALLIGIGVGVAAALRLALSDELAGLLVVRSKGTDFTTMAVVGAAMVYIASTIDPLGTG
>NZ_CP009483.1|WP_023371284.1|4474760_4475153_-|DUF732-domain-containing-protein
MRTWRHQPLTIRLLAGSAVLLTAAAALAAPAEAGTIDDAFIGALNDAGVNYGDPASAVDLGHSVCSTLARPGGSFNSAAATVVAAGTGMPQPMAQIFTSIAISTYCPQAMTDVATGNLPGLPQIPGIPGF
>NZ_CP009483.1|WP_036391037.1|4475360_4476803_+|FAD-binding-oxidoreductase
MRPMISRQAFLRGAVGALATSAVFGHVRAAADPSSGWTGLASSIGGRVLLPDSGGSFTSGKQIFNSLYNGSNPAAVVTVTSQADVEKAVAFAAANKLKIAPRGGGHSYIGASAAAGAMVIDLRGLTGGVNFDSATGNVTMPAATDLYAVQQALAGAGRAIPTGSCPTVGVGGLTLGGGMGADSRHAGLTCDALRSATVVLPGGETVTASADDHPDLFWALRGGGGGNFGVTTSMTFATFPTADSDVVRVDFAPSSAAQVLTGWQTWLAAADRNTWGLVDMSVSASQANCHVLATCPAGSGPAVANAIKSAVGVQPTGVEHKTLSHMDLVMYLAGGSATSSPRSFVAGSDVIGTMNSAAAQSIVAALGKWPPASGRASVIVDTLSGAVGDVDPSGSAFPWRRQSAVAQWYVETPGSGQVAAANKWIGAAHQAVQQFSVGAYVNYLEPNTAPARYFGPNLARLTAIRQRYDPGQLMYSGIVF

Crispr_ID: NZ_CP009483_16

• CRISPR_ID: NZ_CP009483_16
• CRISPR_location: 4864293-4864540
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP009483_16

Consensus_repeat	Method
CGCCGACGGCGACACCAACATCGCCACCTTCGCCA	PILER-CR

spacers of NZ_CP009483_16

>16.1|4864328|41|NZ_CP009483|PILER-CR
AGCAACGTAATCGGCAACGCCAACAGCGGCATCGCAACCAG
>16.2|4864404|52|NZ_CP009483|PILER-CR
CCGTGGTCGGCAACGGCAACCATGGGGCTGGCGCCGATGCCGTCGGCCGCCT
>16.3|4864491|34|NZ_CP009483|PILER-CR
CTGCAGTCGGCGGCGGGAACGAGGTCGGCGCGAG

CRISPR arrays and Neighbor proteins around NZ_CP009483_16

CRISPR arrays

The CRISPR arrays of NZ_CP009483_16

>merge|NZ_CP009483|16|4864293-4864540|PILER-CR
CGCCGTCGGCAACACCAACATCGCCACGTTCAGCAACGTAATCGGCAACGCCAACAGCGGCATCGCAACCAGCACCGATGGCGATACCAACATCGCCACCTTCGCGACCGTGGTCGGCAACGGCAACCATGGGGCTGGCGCCGATGCCGTCGGCCGCCTCAACATCGCCACCTTCGGCACTGCAGTCGGCGGCGGGAACGAGGTCGGCGCGAGCGCCAACGGCGACACCAACATCGCTACCTTCGCCA

>NZ_CP009483|16|1|4864293-4864540|PILER-CR
CGCCGTCGGCAACACCAACATCGCCACGTTCAGCA	ACGTAATCGGCAACGCCAACAGCGGCATCGCAACCAGCACC
GATGGCGATACCAACATCGCCACCTTCGCGACCGT	GGTCGGCAACGGCAACCATGGGGCTGGCGCCGATGCCGTCGGCCGCCTCAAC
ATCGCCACCTTCGGCACTGCAGTCGGCGGCGGGAA	CGAGGTCGGCGCGAGCGCCAACGGCGACACCAAC
ATCGCTACCTTCGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein	unknown	unknown	gnl|CDD|377274
NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein	unknown	unknown	gnl|CDD|369775
NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein	unknown	unknown	gnl|CDD|223659
NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|176203
NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|226039
NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl|CDD|163676
NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase	unknown	unknown	gnl|CDD|378915
NZ_CP009483.1|WP_023371919.1|4870044_4870383_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|223816
NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein	unknown	unknown	gnl|CDD|270703
NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173838
NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl|CDD|235797
NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|226472
NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A	unknown	unknown	gnl|CDD|181171
NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl|CDD|181115

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	9.24652e-07
NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein	gnl|CDD|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	7.14033e-36
NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein	gnl|CDD|369775	pfam08237, PE-PPE, PE-PPE domain. This domain is found C terminal to the PE (pfam00934) and PPE (pfam00823) domains. The secondary structure of this domain is predicted to be a mixture of alpha helices and beta strands.	6.82461e-82
NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	7.48874e-27
NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	6.45138e-74
NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein	gnl|CDD|176203	cd08241, QOR1, Quinone oxidoreductase (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.5887e-132
NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase	gnl|CDD|226039	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	4.64335e-27
NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	4.63897e-152
NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase	gnl|CDD|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	1.49947e-120
NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.000216441
NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.3356e-15
NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	0.00136066
NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C	gnl|CDD|181115	PRK07785, PRK07785, NADH dehydrogenase subunit C; Provisional.	1.25775e-155
NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	3.94776e-102
NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B	gnl|CDD|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	7.87269e-101
NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.0117e-49
NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein	gnl|CDD|226472	COG3963, COG3963, Phospholipid N-methyltransferase [Lipid metabolism].	5.10399e-20
NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A	gnl|CDD|181171	PRK07928, PRK07928, NADH dehydrogenase subunit A; Validated.	7.35513e-73
NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	1.07571e-64

Protein sequences

>NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein
MNFSVLPPEINSVRIFAGAGPQPMLAAATAWDGLAGELAGAASSFSSVASGLVDGSWRGPASAAMAAAAAPYARWLSAAAGHASGAAAQARAVARAFDAARAATVHPLMVAINRNRFVQLVASNVLGLNAPAIASAEAQYEQMWAQDVVAMLGYHADTSAAAAALSPWGAGPQGNSAGSGQSGTSEMPASGRGPVASAISAGSSAAAGTNISLSNLGFGNTGNGNFGSGNAGDLNLGSGNNGNVNLGSGNNGNVNFGSGNTGNVNLGSGNAGSLNAGSGNAGNNNLGSGNNGDANLGHGNVGSNNFGSGNIGGGNLGFGNAGSNNFGSGNNGSGNLGSGNGGNLNVGFANTGNNNIGFANTGNNNIGIGLTGDNQIGFGGLNSGTGNVGLFNSGSGNTGIFNSGSNNLGWLNSGVGNWGGWNSGMGSTGFGNSGVTSTGFWNSGSYDTGFGNAGSGNAGAFNAGSHNTGWFNSGSGSTGDYNSGDGNFGSFNAGDVNTGSFNAGSVNTGLWNSGHTNTGALNSGTLNTGFGSSIIQTVANSGFGNTGTGNSGFNNFGDNNSGYGNAGVAGGPGQNNAGIGNQGTLHSGIGNTGSNNDSGFGNTGFYNVGFFNTGDNNSGFGNINDVASGFNSGIGNFGNSNSGGFNIGTGWAGFFGSNF
>NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase
MPSSTTEAIAEVADRLFTAIENSDRAAVARMWSDDIAVWRAGAHRDDDKARALRVIDWFVSATAERRYEVLDRQIFEDGSGRGFVQQHVLHAAGQTGQSIELRVCIVIKLDTEGLINRIDEYFDPAELAPLLG
>NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein
MTTLETLLSDPDAAGAWNLVPDRSAVTFKVKNMWGLLAVKGEFTKFVGRGNLTDQGTVSGYLEVDVASLRTGIRLRDKHLLSADFFEVERFPEIRVVVTALHPTKGKHAELQASFTIKGITDPVTLPVTVTEFSDGSVRIAGETEIDRVQFGLRWNKFGILAVTATASGEVCFVKAP
>NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein
MSFWVLPPEINSLRMFIGAGSAPMLQAATAWAGLADELGAAAQSFASVTSGLAGQAWQGPAAAAMAAAAAPYAAWLSAAAAQSAGAAGQARAMVSMFEAAQAATVLPAAVAANRDAFVQLVMSNLFGQNAPAIAFAESIYEEMWAADVSAMSGYYSGAAALASQLVPWQSILKGLPGMGSAGAAGTSAGSGAAGTTNVGGNGEGANVAGGDNAGGASGGPVGGETTNVVNSSTSAGLAQADPMYSNVGQGTAGSGNVGSASLLSGGTTSASGGVATPGMMGVPIPIPATGGNQTGSAGIGVGAGSAGNAAPTRVPEAAAPPAAEVEAAAPQLRVLPNADPEIAAKAAPVPVARVTQSTGSGIPESALRPSRTADVSHRSANTQDQASEAEEKVVSLRPEAEKGKLRPRAKQEPGIQMRGG
>NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein
METFILSHHSYLLLPLLTATGIPVPEEVVTVAAGALSSPSVGRLEPGLAILACLAGVLVGDCALYWIGRGLGQTHLGRYHWFARLVDSDRTGHVERILQQHGVKVFLLVRFLLGMRTPLYLAIGALKMDFRRFLVCDVVCATLAVGIFFLLSYLGAGWISGLIHRSEWAATAILLVTAVTGGLYYGVWKRWRVQLSAHGPRLQGKAQ
>NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein
MRDIGRRHFLLTQLSRRWMDQRTDSPVGMGGDCDLAGDGCDRRIVLRRLEALARAIERARAPITRKSTMTQQSPDTTLFFREFCGKFETTGSVMPSTRYLARAMTRHLRRRGPAPIRVLDCGPGTGAFTDRIVDHLRPGDRLDVVEINDSFVRVLQRRFATEPRWQAASNFTNIHEVPFQYFDAAEPYDFIISSLPHSNFPAITVAEILHSYTRLLKPGGVLTYVEYLYLRQIRRTLSRGTQRARIRSVEQLMLSHMSEHEVAHENVLRNVPPARVHHLIAPADGTGGNTGRDWNTLSA
>NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator
MPDSSDALRILVYSNNVQTRQQVMRALGKRLHPDLPELTYVEIATAPMVIQRMDEGGIDLAILDGEATPAGGMGIAKQLKDELSTCPPILVLTGRPDDSWLASWSRAEAAVSHPIDPIVLGRTALGLLRAPAL
>NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A
MNVYIPILVLAALAAAFAVFSVVIASLAGPSRFNRSKLAAYECGIEPTDSSVSSPHATAGQRFPIKYYLTAMLFIVFDIEIVFLYPWAVSFDALGTFALVEMLIFMLTVFVAYAYVWRRGGLTWD
>NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B
MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDLARFGMERFSATPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLHAILKLHEKIQEMPLGVNRERAIAEAEEAALLARPTIEMRGLLR
>NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C
MSSPDQDPREAIARADEEVIDVRRGMFGVSGTGDTSGYGRLVRQVTLPGSSPRPYGGYFDDIADRLAEALHGEGVEFDDAIEKVVVYPQGEGAELTLHVRRERLPQVAQRLRDEPELRFEMCLGVNGVHYPHETGRELHAVYPLQSITHNRRLRLEVSVPDSDPHIPSLYSVYPTNDWHERETYDFFGIVFDGHPSLTRIEMPDDWHGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
>NZ_CP009483.1|WP_023371919.1|4870044_4870383_-|hypothetical-protein
MTGLHGRPTAAELVAAVADFLEGDVRAATSGQVNFHARVAANALRMVERELLSSGDAEVRTALADLGFADEAALAAAIRAGELDGRDEEVMACLRALVRHRLAVAHPGYDSE
>NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein
MTLLEDLAALLDPLLGAEVAIENLRVLTGGASRTTWAFDAVVGAERRPLILRIGPPDDVHAGMELEARVQAAAAAAGAPVPHILLADDSPAALGNPFLICEEVKGETIVRRIQRQLDDPGRTRLLRQCARALAAIHRAEWNGLGLVREDPLGQWRDRLDSMGDTTATFEWAFRWLRARRPPPSTAVLVHGDFRMGNLIVDGSDLAAVLDWELVHVGEAYEDLAWFCVRAWRFGAPASLGAGGLGSIESLLQAYEEAGGATVDRAAFRWWLVLATLRWGVICRYQAERHLSGRTRSVELAAIGRRVCENEWDLLELLEAVGR
>NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase
MDFSLPEHLPGLLAEMDEFIESDIKPLERQHIQYFDHRREHARTDWDNGGVPRREWEDLLAEMRRRADQAGWLRYGLPSRFGGRDGTNVDMAVIREHLAHKGLGLHNDLQNESSIVGNFPQVIMMDRFGTEAQKKEWTEALITGERSMAFGLTEPSHGSDATWLETRAERDGNSWVINGAKRFNTGVHRATHDLVFARTSGEPGQARGITAFLVPTDTPGFTVPYYWWTLNMPTDHGEVALEDVRVSGDAVLGEVDRGLEVGQTFLHENRIRQAASSLGAAQYCIDRAVDYANERRVFGKPLSVNQAVQWPLVELQTEAQMVRLLVYYAADQLDRNHHMEVSDKVAMANYRANRLVCEAADRAMQVFGGMGYSRHEPFEHIYRHHRRYRITEGAEEIQIRRVAQRLFKFGKK
>NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator
MAAGVLTAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFSDKEDLLAALAESFLHDVVAPSGLSVHLPDTPDDDTFFTSVVTGYWNIFKQNIGIMIAVAQLAATQRRFAAVQNEFRRFGMDIVAASVRRAQEQGYGAELHPQHTAAAIALLFENFTTVFVGRSGPENLRLDISDEDAIKTLSMIWKKTLYGT
>NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase
MNQHVTIREVSLRDGLQIEKPIPLAAKLELLAAIAATGVREVEATAFVSPSKVPAMADAAELAAELHRYPDIEFSALVASPNGAKRAIAAGLRAIEYVVAASDSFSAANVGRSSAEATSQIGEILAIARGSGVIVEVIVATAWDCPFDGPTPSQRVLDIAAVARGLGVDRFSIADTIGTATPGRVSSLIAQLHPVIGDIALGGHFHNTRGAGLASAYAAVCSGVTRLDASVGGLGGCPFAPGATGNIATEDLVYLLADSGFEVHIDLPAAIAAAEVAKSVVGHDLPGALLRAGDRIRN
>NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase
MTAPTGPLDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEPPGAPDPLRTWGQAELNGHHVFWTVHARNKRAVTLDLRRPRGRELFLELVEKSDIAVENFRPGTLEKWNLGYDVLSERNPGIILVRVSGYGQTGPDAHKAGYASVAEAASGLRHLNGFPGGPPPRLALSLGDTLAGMFGAQGALAALYRRGVTGRGQVVDVALTESCLAVQESTIPDYDVGGVVRGPSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFARLCKAMGRPELVTDERFATHGARGRNQDELDAIIGAWAAERRPGEIIETLSAAGVIAGPINTVAEVVDDPQLRARGMLVEHYDERVERSVLGPGIVPVLSESPGRVRSAGPPHPGRHNDDVYIGLLGKTVEELTDLRAEGVL
>NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase
MTTRHDYQRIPYLVAFQNNSGVRDVYGGLAEITVLESYLLRPSDKPSDTALVFMHPIGGGAYLPMINALARAGHHVIYCNSRFRGTDSGLLMEKVVEDLGECIKDAKARLGYQKVVLAGWSGGGSLSMFYQQQAQHATVTSSPSGDGPDLTRLDLPAADGIMLLAAHISRHGTLTEWLDASILDETDPTKRDPELDLYHPDNPNQPPYSQEFLARYRQAQIDRNRRITAWVKDKLAELAARGRPDDEFCFVVHGTMADPRWLDPTVDPNERTPGTCYLGDPRVVNMSPVGLARFCSLRSWLSQWSYDDARGDGVACARDLAVPALVIGNLADDACTPSHTRRLFDAIGNSDKEMYEIPGATHYYAGPNQRDKLAHAVDVVTDWLIRHDFASTR
>NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase
MESFVHLRKGRTPRRLHADLDGLKDDELGRGGFTGRTANIYRRHDPTAYRAVGPLRPLDVLSDDLKPSDATDANGGPLLMFHNIDCRILLSRRHQAMPFYTRHVDGDLLCFVHRGSGMAETEFGPLRYREGDWVYIPKACTWRQIPDSETTLLMVEAADEFRVPAPGALGRHFPFDPSQITIPEPAPIDDDDRDQYEVRLIHRPLAEGVPTSLYYQHNPIDVEGWRGDNFPFTFNIGDYNVVTSNSVHLPPTVHLFMQATGVYVMNFLPKPAEGIPGTERTPWYHRNVDYDEIAFFHGGSLYGIPMPPGLISHAPQGVHHGAPEKARQRARRKFDEYSTVDWQVIAIDTRRRLTPCAEMLAHDLGQH
>NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein
MEFLTLPPEVNSARILRGPGPAPLRAAATAWATLSEDLASSATAVSSVMSEISGSAWQGPAAAAMAAAVAPYPGWLGAAATRAAAAGRHAATAAAAYETARTATVPLEMLAQNRSRLVSLVAADVLGLNAPAIAATEAHYEQLWAQDVGAMAGYYAGASAAVAQLTPWQTLLSTLESPVGGMKAAEAAVSASSPSASTAATGVTLVIGGSGYPIPSQSYVNTVVADYVTPTFPGFTTANAQSLYTPAQSYWITGVKTLTEDASWAQGLTILDNAIHAQLATGNNVAVQGFSQGAGIASLEMANLKAEGVPTSSVSFSLIGDPMNPNGGLYSRFDGLTLASMGKSFPGSTPANDYPTVIYTIEYDGFADFPQYPLNLVADANAMLGALYVHPQYPVLTPAQVVTAVQLPTQGPTTTTYYMIPTQNLPLLEPLRALPLGNTVADLIQPDLKVIVNLGYGNPDYGYSTGPANVPTPFGLFPDASPGVVVADLIDGTRQGIGAAAADLGTWHAPAGNPAPNPFALSDLTPPTVAATTIDGIIQGLQTGNTNLTNAVTSATSSAYATLLPTADMLSAILVSLPSYDVNLFLDGVRQALDGDPAGIINAIGYPIAADTGLLTFLSFFLAYAYYGAAKSIAGDFASLI
>NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein
MRAIRVTRLEGPGAVEISEIDEPAGEGVVVDVYAAGAAFPDALLTRGLYQYRPEPPFVLGAEIAGVVRSAPQDAHVCAGDRVVGLTMLTGGMAEVAVLSPDRVFKLPDNVSFEAGAGLLFNDLTVYFALRVRGRLQRGETVLVHGAAGGIGTSALRLAPVLGASRTIAVVSTEEKAAIATAAGATDVVLAEGFKDAVKALTDGRGVDVVVDPVGGDRFTDSLRSLAPAGRLLVIGFTGGEIPTVKVNRLLLNNIDVVGVGWGAWAGKHPGALSEQWAALEQLLSSGELPPPEPVVYPLEQAAAAVASLENRTAKGKVVLRVRD

Crispr_ID: NZ_CP009483_17

• CRISPR_ID: NZ_CP009483_17
• CRISPR_location: 4868284-4868673
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NZ_CP009483_17

Consensus_repeat	Method
ACGGCGGCGACGGTGGTGGGTGAT	PILER-CR

spacers of NZ_CP009483_17

>17.1|4868308|48|NZ_CP009483|PILER-CR
GCCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATGTGGCC
>17.2|4868380|48|NZ_CP009483|PILER-CR
GACAATGGTGGGGTTGTGGCGGGGTCGAGCGGTGACACGAATATTGCG
>17.3|4868452|48|NZ_CP009483|PILER-CR
CGTAATGCTGGGGTGTTGGCCAGTGCGCAGGGGGTGCGCAATATTGCG
>17.4|4868524|54|NZ_CP009483|PILER-CR
GACAATGTGATTGATGCGGCGAGTGCGATCGCGGTGGGGGAGACCAATGTTGGT
>17.5|4868602|48|NZ_CP009483|PILER-CR
GCCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATGTGGCC

CRISPR arrays and Neighbor proteins around NZ_CP009483_17

CRISPR arrays

The CRISPR arrays of NZ_CP009483_17

>merge|NZ_CP009483|17|4868284-4868673|PILER-CR
ACGGCGGCGACGGTGGTTGGTGATGCCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATGTGGCCACGGCGGCCACGGTGGTGGGTGCCGACAATGGTGGGGTTGTGGCGGGGTCGAGCGGTGACACGAATATTGCGACGGCGGCGGCGGTGGTGGGGGATCGTAATGCTGGGGTGTTGGCCAGTGCGCAGGGGGTGCGCAATATTGCGACGGCGGCGACGGTGGTGGGTAATGACAATGTGATTGATGCGGCGAGTGCGATCGCGGTGGGGGAGACCAATGTTGGTACGGCGGCGACGGTGGTTGGTGATGCCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATGTGGCCACGGCGGCGACGGTGGTTGGTGAT

>NZ_CP009483|17|2|4868284-4868673|PILER-CR
ACGGCGGCGACGGTGGTTGGTGAT	GCCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATGTGGCC
ACGGCGGCCACGGTGGTGGGTGCC	GACAATGGTGGGGTTGTGGCGGGGTCGAGCGGTGACACGAATATTGCG
ACGGCGGCGGCGGTGGTGGGGGAT	CGTAATGCTGGGGTGTTGGCCAGTGCGCAGGGGGTGCGCAATATTGCG
ACGGCGGCGACGGTGGTGGGTAAT	GACAATGTGATTGATGCGGCGAGTGCGATCGCGGTGGGGGAGACCAATGTTGGT
ACGGCGGCGACGGTGGTTGGTGAT	GCCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATGTGGCC
ACGGCGGCGACGGTGGTTGGTGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein	unknown	unknown	gnl|CDD|377274
NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein	unknown	unknown	gnl|CDD|369775
NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein	unknown	unknown	gnl|CDD|223659
NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|176203
NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|226039
NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl|CDD|163676
NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase	unknown	unknown	gnl|CDD|378915
NZ_CP009483.1|WP_023371919.1|4870044_4870383_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|223816
NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein	unknown	unknown	gnl|CDD|270703
NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173838
NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl|CDD|235797
NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|226472
NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A	unknown	unknown	gnl|CDD|181171
NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl|CDD|181115

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	9.24652e-07
NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein	gnl|CDD|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	7.14033e-36
NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein	gnl|CDD|369775	pfam08237, PE-PPE, PE-PPE domain. This domain is found C terminal to the PE (pfam00934) and PPE (pfam00823) domains. The secondary structure of this domain is predicted to be a mixture of alpha helices and beta strands.	6.82461e-82
NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	7.48874e-27
NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	6.45138e-74
NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein	gnl|CDD|176203	cd08241, QOR1, Quinone oxidoreductase (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.5887e-132
NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase	gnl|CDD|226039	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	4.64335e-27
NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	4.63897e-152
NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase	gnl|CDD|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	1.49947e-120
NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.000216441
NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.3356e-15
NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	0.00136066
NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C	gnl|CDD|181115	PRK07785, PRK07785, NADH dehydrogenase subunit C; Provisional.	1.25775e-155
NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	3.94776e-102
NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B	gnl|CDD|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	7.87269e-101
NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.0117e-49
NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein	gnl|CDD|226472	COG3963, COG3963, Phospholipid N-methyltransferase [Lipid metabolism].	5.10399e-20
NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A	gnl|CDD|181171	PRK07928, PRK07928, NADH dehydrogenase subunit A; Validated.	7.35513e-73
NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	1.07571e-64

Protein sequences

>NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein
MNFSVLPPEINSVRIFAGAGPQPMLAAATAWDGLAGELAGAASSFSSVASGLVDGSWRGPASAAMAAAAAPYARWLSAAAGHASGAAAQARAVARAFDAARAATVHPLMVAINRNRFVQLVASNVLGLNAPAIASAEAQYEQMWAQDVVAMLGYHADTSAAAAALSPWGAGPQGNSAGSGQSGTSEMPASGRGPVASAISAGSSAAAGTNISLSNLGFGNTGNGNFGSGNAGDLNLGSGNNGNVNLGSGNNGNVNFGSGNTGNVNLGSGNAGSLNAGSGNAGNNNLGSGNNGDANLGHGNVGSNNFGSGNIGGGNLGFGNAGSNNFGSGNNGSGNLGSGNGGNLNVGFANTGNNNIGFANTGNNNIGIGLTGDNQIGFGGLNSGTGNVGLFNSGSGNTGIFNSGSNNLGWLNSGVGNWGGWNSGMGSTGFGNSGVTSTGFWNSGSYDTGFGNAGSGNAGAFNAGSHNTGWFNSGSGSTGDYNSGDGNFGSFNAGDVNTGSFNAGSVNTGLWNSGHTNTGALNSGTLNTGFGSSIIQTVANSGFGNTGTGNSGFNNFGDNNSGYGNAGVAGGPGQNNAGIGNQGTLHSGIGNTGSNNDSGFGNTGFYNVGFFNTGDNNSGFGNINDVASGFNSGIGNFGNSNSGGFNIGTGWAGFFGSNF
>NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase
MPSSTTEAIAEVADRLFTAIENSDRAAVARMWSDDIAVWRAGAHRDDDKARALRVIDWFVSATAERRYEVLDRQIFEDGSGRGFVQQHVLHAAGQTGQSIELRVCIVIKLDTEGLINRIDEYFDPAELAPLLG
>NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein
MTTLETLLSDPDAAGAWNLVPDRSAVTFKVKNMWGLLAVKGEFTKFVGRGNLTDQGTVSGYLEVDVASLRTGIRLRDKHLLSADFFEVERFPEIRVVVTALHPTKGKHAELQASFTIKGITDPVTLPVTVTEFSDGSVRIAGETEIDRVQFGLRWNKFGILAVTATASGEVCFVKAP
>NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein
MSFWVLPPEINSLRMFIGAGSAPMLQAATAWAGLADELGAAAQSFASVTSGLAGQAWQGPAAAAMAAAAAPYAAWLSAAAAQSAGAAGQARAMVSMFEAAQAATVLPAAVAANRDAFVQLVMSNLFGQNAPAIAFAESIYEEMWAADVSAMSGYYSGAAALASQLVPWQSILKGLPGMGSAGAAGTSAGSGAAGTTNVGGNGEGANVAGGDNAGGASGGPVGGETTNVVNSSTSAGLAQADPMYSNVGQGTAGSGNVGSASLLSGGTTSASGGVATPGMMGVPIPIPATGGNQTGSAGIGVGAGSAGNAAPTRVPEAAAPPAAEVEAAAPQLRVLPNADPEIAAKAAPVPVARVTQSTGSGIPESALRPSRTADVSHRSANTQDQASEAEEKVVSLRPEAEKGKLRPRAKQEPGIQMRGG
>NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein
METFILSHHSYLLLPLLTATGIPVPEEVVTVAAGALSSPSVGRLEPGLAILACLAGVLVGDCALYWIGRGLGQTHLGRYHWFARLVDSDRTGHVERILQQHGVKVFLLVRFLLGMRTPLYLAIGALKMDFRRFLVCDVVCATLAVGIFFLLSYLGAGWISGLIHRSEWAATAILLVTAVTGGLYYGVWKRWRVQLSAHGPRLQGKAQ
>NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein
MRDIGRRHFLLTQLSRRWMDQRTDSPVGMGGDCDLAGDGCDRRIVLRRLEALARAIERARAPITRKSTMTQQSPDTTLFFREFCGKFETTGSVMPSTRYLARAMTRHLRRRGPAPIRVLDCGPGTGAFTDRIVDHLRPGDRLDVVEINDSFVRVLQRRFATEPRWQAASNFTNIHEVPFQYFDAAEPYDFIISSLPHSNFPAITVAEILHSYTRLLKPGGVLTYVEYLYLRQIRRTLSRGTQRARIRSVEQLMLSHMSEHEVAHENVLRNVPPARVHHLIAPADGTGGNTGRDWNTLSA
>NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator
MPDSSDALRILVYSNNVQTRQQVMRALGKRLHPDLPELTYVEIATAPMVIQRMDEGGIDLAILDGEATPAGGMGIAKQLKDELSTCPPILVLTGRPDDSWLASWSRAEAAVSHPIDPIVLGRTALGLLRAPAL
>NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A
MNVYIPILVLAALAAAFAVFSVVIASLAGPSRFNRSKLAAYECGIEPTDSSVSSPHATAGQRFPIKYYLTAMLFIVFDIEIVFLYPWAVSFDALGTFALVEMLIFMLTVFVAYAYVWRRGGLTWD
>NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B
MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDLARFGMERFSATPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLHAILKLHEKIQEMPLGVNRERAIAEAEEAALLARPTIEMRGLLR
>NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C
MSSPDQDPREAIARADEEVIDVRRGMFGVSGTGDTSGYGRLVRQVTLPGSSPRPYGGYFDDIADRLAEALHGEGVEFDDAIEKVVVYPQGEGAELTLHVRRERLPQVAQRLRDEPELRFEMCLGVNGVHYPHETGRELHAVYPLQSITHNRRLRLEVSVPDSDPHIPSLYSVYPTNDWHERETYDFFGIVFDGHPSLTRIEMPDDWHGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
>NZ_CP009483.1|WP_023371919.1|4870044_4870383_-|hypothetical-protein
MTGLHGRPTAAELVAAVADFLEGDVRAATSGQVNFHARVAANALRMVERELLSSGDAEVRTALADLGFADEAALAAAIRAGELDGRDEEVMACLRALVRHRLAVAHPGYDSE
>NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein
MTLLEDLAALLDPLLGAEVAIENLRVLTGGASRTTWAFDAVVGAERRPLILRIGPPDDVHAGMELEARVQAAAAAAGAPVPHILLADDSPAALGNPFLICEEVKGETIVRRIQRQLDDPGRTRLLRQCARALAAIHRAEWNGLGLVREDPLGQWRDRLDSMGDTTATFEWAFRWLRARRPPPSTAVLVHGDFRMGNLIVDGSDLAAVLDWELVHVGEAYEDLAWFCVRAWRFGAPASLGAGGLGSIESLLQAYEEAGGATVDRAAFRWWLVLATLRWGVICRYQAERHLSGRTRSVELAAIGRRVCENEWDLLELLEAVGR
>NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase
MDFSLPEHLPGLLAEMDEFIESDIKPLERQHIQYFDHRREHARTDWDNGGVPRREWEDLLAEMRRRADQAGWLRYGLPSRFGGRDGTNVDMAVIREHLAHKGLGLHNDLQNESSIVGNFPQVIMMDRFGTEAQKKEWTEALITGERSMAFGLTEPSHGSDATWLETRAERDGNSWVINGAKRFNTGVHRATHDLVFARTSGEPGQARGITAFLVPTDTPGFTVPYYWWTLNMPTDHGEVALEDVRVSGDAVLGEVDRGLEVGQTFLHENRIRQAASSLGAAQYCIDRAVDYANERRVFGKPLSVNQAVQWPLVELQTEAQMVRLLVYYAADQLDRNHHMEVSDKVAMANYRANRLVCEAADRAMQVFGGMGYSRHEPFEHIYRHHRRYRITEGAEEIQIRRVAQRLFKFGKK
>NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator
MAAGVLTAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFSDKEDLLAALAESFLHDVVAPSGLSVHLPDTPDDDTFFTSVVTGYWNIFKQNIGIMIAVAQLAATQRRFAAVQNEFRRFGMDIVAASVRRAQEQGYGAELHPQHTAAAIALLFENFTTVFVGRSGPENLRLDISDEDAIKTLSMIWKKTLYGT
>NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase
MNQHVTIREVSLRDGLQIEKPIPLAAKLELLAAIAATGVREVEATAFVSPSKVPAMADAAELAAELHRYPDIEFSALVASPNGAKRAIAAGLRAIEYVVAASDSFSAANVGRSSAEATSQIGEILAIARGSGVIVEVIVATAWDCPFDGPTPSQRVLDIAAVARGLGVDRFSIADTIGTATPGRVSSLIAQLHPVIGDIALGGHFHNTRGAGLASAYAAVCSGVTRLDASVGGLGGCPFAPGATGNIATEDLVYLLADSGFEVHIDLPAAIAAAEVAKSVVGHDLPGALLRAGDRIRN
>NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase
MTAPTGPLDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEPPGAPDPLRTWGQAELNGHHVFWTVHARNKRAVTLDLRRPRGRELFLELVEKSDIAVENFRPGTLEKWNLGYDVLSERNPGIILVRVSGYGQTGPDAHKAGYASVAEAASGLRHLNGFPGGPPPRLALSLGDTLAGMFGAQGALAALYRRGVTGRGQVVDVALTESCLAVQESTIPDYDVGGVVRGPSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFARLCKAMGRPELVTDERFATHGARGRNQDELDAIIGAWAAERRPGEIIETLSAAGVIAGPINTVAEVVDDPQLRARGMLVEHYDERVERSVLGPGIVPVLSESPGRVRSAGPPHPGRHNDDVYIGLLGKTVEELTDLRAEGVL
>NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase
MTTRHDYQRIPYLVAFQNNSGVRDVYGGLAEITVLESYLLRPSDKPSDTALVFMHPIGGGAYLPMINALARAGHHVIYCNSRFRGTDSGLLMEKVVEDLGECIKDAKARLGYQKVVLAGWSGGGSLSMFYQQQAQHATVTSSPSGDGPDLTRLDLPAADGIMLLAAHISRHGTLTEWLDASILDETDPTKRDPELDLYHPDNPNQPPYSQEFLARYRQAQIDRNRRITAWVKDKLAELAARGRPDDEFCFVVHGTMADPRWLDPTVDPNERTPGTCYLGDPRVVNMSPVGLARFCSLRSWLSQWSYDDARGDGVACARDLAVPALVIGNLADDACTPSHTRRLFDAIGNSDKEMYEIPGATHYYAGPNQRDKLAHAVDVVTDWLIRHDFASTR
>NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase
MESFVHLRKGRTPRRLHADLDGLKDDELGRGGFTGRTANIYRRHDPTAYRAVGPLRPLDVLSDDLKPSDATDANGGPLLMFHNIDCRILLSRRHQAMPFYTRHVDGDLLCFVHRGSGMAETEFGPLRYREGDWVYIPKACTWRQIPDSETTLLMVEAADEFRVPAPGALGRHFPFDPSQITIPEPAPIDDDDRDQYEVRLIHRPLAEGVPTSLYYQHNPIDVEGWRGDNFPFTFNIGDYNVVTSNSVHLPPTVHLFMQATGVYVMNFLPKPAEGIPGTERTPWYHRNVDYDEIAFFHGGSLYGIPMPPGLISHAPQGVHHGAPEKARQRARRKFDEYSTVDWQVIAIDTRRRLTPCAEMLAHDLGQH
>NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein
MEFLTLPPEVNSARILRGPGPAPLRAAATAWATLSEDLASSATAVSSVMSEISGSAWQGPAAAAMAAAVAPYPGWLGAAATRAAAAGRHAATAAAAYETARTATVPLEMLAQNRSRLVSLVAADVLGLNAPAIAATEAHYEQLWAQDVGAMAGYYAGASAAVAQLTPWQTLLSTLESPVGGMKAAEAAVSASSPSASTAATGVTLVIGGSGYPIPSQSYVNTVVADYVTPTFPGFTTANAQSLYTPAQSYWITGVKTLTEDASWAQGLTILDNAIHAQLATGNNVAVQGFSQGAGIASLEMANLKAEGVPTSSVSFSLIGDPMNPNGGLYSRFDGLTLASMGKSFPGSTPANDYPTVIYTIEYDGFADFPQYPLNLVADANAMLGALYVHPQYPVLTPAQVVTAVQLPTQGPTTTTYYMIPTQNLPLLEPLRALPLGNTVADLIQPDLKVIVNLGYGNPDYGYSTGPANVPTPFGLFPDASPGVVVADLIDGTRQGIGAAAADLGTWHAPAGNPAPNPFALSDLTPPTVAATTIDGIIQGLQTGNTNLTNAVTSATSSAYATLLPTADMLSAILVSLPSYDVNLFLDGVRQALDGDPAGIINAIGYPIAADTGLLTFLSFFLAYAYYGAAKSIAGDFASLI
>NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein
MRAIRVTRLEGPGAVEISEIDEPAGEGVVVDVYAAGAAFPDALLTRGLYQYRPEPPFVLGAEIAGVVRSAPQDAHVCAGDRVVGLTMLTGGMAEVAVLSPDRVFKLPDNVSFEAGAGLLFNDLTVYFALRVRGRLQRGETVLVHGAAGGIGTSALRLAPVLGASRTIAVVSTEEKAAIATAAGATDVVLAEGFKDAVKALTDGRGVDVVVDPVGGDRFTDSLRSLAPAGRLLVIGFTGGEIPTVKVNRLLLNNIDVVGVGWGAWAGKHPGALSEQWAALEQLLSSGELPPPEPVVYPLEQAAAAVASLENRTAKGKVVLRVRD

Crispr_ID: NZ_CP009483_18

• CRISPR_ID: NZ_CP009483_18
• CRISPR_location: 4868861-4869328
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP009483_18

Consensus_repeat	Method
TNGCNACGGCGGCNACGGTGGTNGGTGATG	CRT

spacers of NZ_CP009483_18

>18.1|4868891|42|NZ_CP009483|CRT
CCAACAATGGGGTGGCGGCCGGTGCGGATGGCAGCCTCAACA
>18.2|4868963|42|NZ_CP009483|CRT
ACAATGGTGGGGTTGTGGCGGGGGCGAGCGGTGACACGAACA
>18.3|4869035|42|NZ_CP009483|CRT
GTAATGCTGGGGTGTTGGCCAGTTCGCAGGGGGTGCGCAATA
>18.4|4869107|48|NZ_CP009483|CRT
ACAATGTGATTGATGCGGCGAGTGCGATCGCGGTGGGGGAGACCAATG
>18.5|4869185|42|NZ_CP009483|CRT
CCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATG
>18.6|4869257|42|NZ_CP009483|CRT
GCAATAGTGGAGTTACGGCGGATGCGGATGGCAGTGTCAATG

CRISPR arrays and Neighbor proteins around NZ_CP009483_18

CRISPR arrays

The CRISPR arrays of NZ_CP009483_18

>merge|NZ_CP009483|18|4868861-4869328|CRT
TTGCAACGGCGGCCACGGTGGTGGGCAACGCCAACAATGGGGTGGCGGCCGGTGCGGATGGCAGCCTCAACATCGCGACGGCGGCCACGGTGGTGGGTGCCGACAATGGTGGGGTTGTGGCGGGGGCGAGCGGTGACACGAACATTGCGACGGCGGCGACGGTGGTGGGGGATCGTAATGCTGGGGTGTTGGCCAGTTCGCAGGGGGTGCGCAATATTGCGACGGCCGCGACGGTGGTGGGTAATGACAATGTGATTGATGCGGCGAGTGCGATCGCGGTGGGGGAGACCAATGTTGGTACGGCGGCGACGGTGGTTGGTGATGCCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATGTGGCCACGGCGGCCACGGCGGTCGGTGATGGCAATAGTGGAGTTACGGCGGATGCGGATGGCAGTGTCAATGTGGTGACGGCGGCGACCGCGGTTTTTGATG

>NZ_CP009483|18|1|4868861-4869328|CRT
TTGCAACGGCGGCCACGGTGGTGGGCAACG	CCAACAATGGGGTGGCGGCCGGTGCGGATGGCAGCCTCAACA
TCGCGACGGCGGCCACGGTGGTGGGTGCCG	ACAATGGTGGGGTTGTGGCGGGGGCGAGCGGTGACACGAACA
TTGCGACGGCGGCGACGGTGGTGGGGGATC	GTAATGCTGGGGTGTTGGCCAGTTCGCAGGGGGTGCGCAATA
TTGCGACGGCCGCGACGGTGGTGGGTAATG	ACAATGTGATTGATGCGGCGAGTGCGATCGCGGTGGGGGAGACCAATG
TTGGTACGGCGGCGACGGTGGTTGGTGATG	CCAATAGTGGGGTGGCGGCTAGTGCGGATGGTCGTATCAATG
TGGCCACGGCGGCCACGGCGGTCGGTGATG	GCAATAGTGGAGTTACGGCGGATGCGGATGGCAGTGTCAATG
TGGTGACGGCGGCGACCGCGGTTTTTGATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein	unknown	unknown	gnl|CDD|377274
NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein	unknown	unknown	gnl|CDD|369775
NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein	unknown	unknown	gnl|CDD|223659
NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|176203
NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|226039
NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl|CDD|163676
NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase	unknown	unknown	gnl|CDD|378915
NZ_CP009483.1|WP_023371919.1|4870044_4870383_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator	unknown	unknown	gnl|CDD|223816
NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein	unknown	unknown	gnl|CDD|270703
NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173838
NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl|CDD|235797
NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|226472
NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A	unknown	unknown	gnl|CDD|181171
NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl|CDD|181115

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	9.24652e-07
NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein	gnl|CDD|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	7.14033e-36
NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein	gnl|CDD|369775	pfam08237, PE-PPE, PE-PPE domain. This domain is found C terminal to the PE (pfam00934) and PPE (pfam00823) domains. The secondary structure of this domain is predicted to be a mixture of alpha helices and beta strands.	6.82461e-82
NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	7.48874e-27
NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	6.45138e-74
NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein	gnl|CDD|176203	cd08241, QOR1, Quinone oxidoreductase (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.5887e-132
NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase	gnl|CDD|226039	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	4.64335e-27
NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	4.63897e-152
NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase	gnl|CDD|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	1.49947e-120
NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.000216441
NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.3356e-15
NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	0.00136066
NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C	gnl|CDD|181115	PRK07785, PRK07785, NADH dehydrogenase subunit C; Provisional.	1.25775e-155
NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	3.94776e-102
NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B	gnl|CDD|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	7.87269e-101
NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.0117e-49
NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein	gnl|CDD|226472	COG3963, COG3963, Phospholipid N-methyltransferase [Lipid metabolism].	5.10399e-20
NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A	gnl|CDD|181171	PRK07928, PRK07928, NADH dehydrogenase subunit A; Validated.	7.35513e-73
NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	1.07571e-64

Protein sequences

>NZ_CP009483.1|WP_036444274.1|4860334_4862314_+|PPE-family-protein
MNFSVLPPEINSVRIFAGAGPQPMLAAATAWDGLAGELAGAASSFSSVASGLVDGSWRGPASAAMAAAAAPYARWLSAAAGHASGAAAQARAVARAFDAARAATVHPLMVAINRNRFVQLVASNVLGLNAPAIASAEAQYEQMWAQDVVAMLGYHADTSAAAAALSPWGAGPQGNSAGSGQSGTSEMPASGRGPVASAISAGSSAAAGTNISLSNLGFGNTGNGNFGSGNAGDLNLGSGNNGNVNLGSGNNGNVNFGSGNTGNVNLGSGNAGSLNAGSGNAGNNNLGSGNNGDANLGHGNVGSNNFGSGNIGGGNLGFGNAGSNNFGSGNNGSGNLGSGNGGNLNVGFANTGNNNIGFANTGNNNIGIGLTGDNQIGFGGLNSGTGNVGLFNSGSGNTGIFNSGSNNLGWLNSGVGNWGGWNSGMGSTGFGNSGVTSTGFWNSGSYDTGFGNAGSGNAGAFNAGSHNTGWFNSGSGSTGDYNSGDGNFGSFNAGDVNTGSFNAGSVNTGLWNSGHTNTGALNSGTLNTGFGSSIIQTVANSGFGNTGTGNSGFNNFGDNNSGYGNAGVAGGPGQNNAGIGNQGTLHSGIGNTGSNNDSGFGNTGFYNVGFFNTGDNNSGFGNINDVASGFNSGIGNFGNSNSGGFNIGTGWAGFFGSNF
>NZ_CP009483.1|WP_036391794.1|4859490_4859892_-|ketosteroid-isomerase
MPSSTTEAIAEVADRLFTAIENSDRAAVARMWSDDIAVWRAGAHRDDDKARALRVIDWFVSATAERRYEVLDRQIFEDGSGRGFVQQHVLHAAGQTGQSIELRVCIVIKLDTEGLINRIDEYFDPAELAPLLG
>NZ_CP009483.1|WP_023371914.1|4858832_4859366_-|YceI-family-protein
MTTLETLLSDPDAAGAWNLVPDRSAVTFKVKNMWGLLAVKGEFTKFVGRGNLTDQGTVSGYLEVDVASLRTGIRLRDKHLLSADFFEVERFPEIRVVVTALHPTKGKHAELQASFTIKGITDPVTLPVTVTEFSDGSVRIAGETEIDRVQFGLRWNKFGILAVTATASGEVCFVKAP
>NZ_CP009483.1|WP_023371913.1|4857554_4858817_+|PPE-family-protein
MSFWVLPPEINSLRMFIGAGSAPMLQAATAWAGLADELGAAAQSFASVTSGLAGQAWQGPAAAAMAAAAAPYAAWLSAAAAQSAGAAGQARAMVSMFEAAQAATVLPAAVAANRDAFVQLVMSNLFGQNAPAIAFAESIYEEMWAADVSAMSGYYSGAAALASQLVPWQSILKGLPGMGSAGAAGTSAGSGAAGTTNVGGNGEGANVAGGDNAGGASGGPVGGETTNVVNSSTSAGLAQADPMYSNVGQGTAGSGNVGSASLLSGGTTSASGGVATPGMMGVPIPIPATGGNQTGSAGIGVGAGSAGNAAPTRVPEAAAPPAAEVEAAAPQLRVLPNADPEIAAKAAPVPVARVTQSTGSGIPESALRPSRTADVSHRSANTQDQASEAEEKVVSLRPEAEKGKLRPRAKQEPGIQMRGG
>NZ_CP009483.1|WP_023371912.1|4856344_4856968_-|DedA-family-protein
METFILSHHSYLLLPLLTATGIPVPEEVVTVAAGALSSPSVGRLEPGLAILACLAGVLVGDCALYWIGRGLGQTHLGRYHWFARLVDSDRTGHVERILQQHGVKVFLLVRFLLGMRTPLYLAIGALKMDFRRFLVCDVVCATLAVGIFFLLSYLGAGWISGLIHRSEWAATAILLVTAVTGGLYYGVWKRWRVQLSAHGPRLQGKAQ
>NZ_CP009483.1|WP_080674118.1|4855652_4856552_-|methyltransferase-domain-containing-protein
MRDIGRRHFLLTQLSRRWMDQRTDSPVGMGGDCDLAGDGCDRRIVLRRLEALARAIERARAPITRKSTMTQQSPDTTLFFREFCGKFETTGSVMPSTRYLARAMTRHLRRRGPAPIRVLDCGPGTGAFTDRIVDHLRPGDRLDVVEINDSFVRVLQRRFATEPRWQAASNFTNIHEVPFQYFDAAEPYDFIISSLPHSNFPAITVAEILHSYTRLLKPGGVLTYVEYLYLRQIRRTLSRGTQRARIRSVEQLMLSHMSEHEVAHENVLRNVPPARVHHLIAPADGTGGNTGRDWNTLSA
>NZ_CP009483.1|WP_023371910.1|4855121_4855523_-|DNA-binding-response-regulator
MPDSSDALRILVYSNNVQTRQQVMRALGKRLHPDLPELTYVEIATAPMVIQRMDEGGIDLAILDGEATPAGGMGIAKQLKDELSTCPPILVLTGRPDDSWLASWSRAEAAVSHPIDPIVLGRTALGLLRAPAL
>NZ_CP009483.1|WP_023371909.1|4854488_4854866_-|NADH-quinone-oxidoreductase-subunit-A
MNVYIPILVLAALAAAFAVFSVVIASLAGPSRFNRSKLAAYECGIEPTDSSVSSPHATAGQRFPIKYYLTAMLFIVFDIEIVFLYPWAVSFDALGTFALVEMLIFMLTVFVAYAYVWRRGGLTWD
>NZ_CP009483.1|WP_023371908.1|4853885_4854440_-|NADH-quinone-oxidoreductase-subunit-B
MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDLARFGMERFSATPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLHAILKLHEKIQEMPLGVNRERAIAEAEEAALLARPTIEMRGLLR
>NZ_CP009483.1|WP_023371907.1|4853169_4853889_-|NADH-quinone-oxidoreductase-subunit-C
MSSPDQDPREAIARADEEVIDVRRGMFGVSGTGDTSGYGRLVRQVTLPGSSPRPYGGYFDDIADRLAEALHGEGVEFDDAIEKVVVYPQGEGAELTLHVRRERLPQVAQRLRDEPELRFEMCLGVNGVHYPHETGRELHAVYPLQSITHNRRLRLEVSVPDSDPHIPSLYSVYPTNDWHERETYDFFGIVFDGHPSLTRIEMPDDWHGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
>NZ_CP009483.1|WP_023371919.1|4870044_4870383_-|hypothetical-protein
MTGLHGRPTAAELVAAVADFLEGDVRAATSGQVNFHARVAANALRMVERELLSSGDAEVRTALADLGFADEAALAAAIRAGELDGRDEEVMACLRALVRHRLAVAHPGYDSE
>NZ_CP009483.1|WP_023371920.1|4870379_4871345_-|phosphotransferase-family-protein
MTLLEDLAALLDPLLGAEVAIENLRVLTGGASRTTWAFDAVVGAERRPLILRIGPPDDVHAGMELEARVQAAAAAAGAPVPHILLADDSPAALGNPFLICEEVKGETIVRRIQRQLDDPGRTRLLRQCARALAAIHRAEWNGLGLVREDPLGQWRDRLDSMGDTTATFEWAFRWLRARRPPPSTAVLVHGDFRMGNLIVDGSDLAAVLDWELVHVGEAYEDLAWFCVRAWRFGAPASLGAGGLGSIESLLQAYEEAGGATVDRAAFRWWLVLATLRWGVICRYQAERHLSGRTRSVELAAIGRRVCENEWDLLELLEAVGR
>NZ_CP009483.1|WP_023371921.1|4871341_4872580_-|acyl-CoA-dehydrogenase
MDFSLPEHLPGLLAEMDEFIESDIKPLERQHIQYFDHRREHARTDWDNGGVPRREWEDLLAEMRRRADQAGWLRYGLPSRFGGRDGTNVDMAVIREHLAHKGLGLHNDLQNESSIVGNFPQVIMMDRFGTEAQKKEWTEALITGERSMAFGLTEPSHGSDATWLETRAERDGNSWVINGAKRFNTGVHRATHDLVFARTSGEPGQARGITAFLVPTDTPGFTVPYYWWTLNMPTDHGEVALEDVRVSGDAVLGEVDRGLEVGQTFLHENRIRQAASSLGAAQYCIDRAVDYANERRVFGKPLSVNQAVQWPLVELQTEAQMVRLLVYYAADQLDRNHHMEVSDKVAMANYRANRLVCEAADRAMQVFGGMGYSRHEPFEHIYRHHRRYRITEGAEEIQIRRVAQRLFKFGKK
>NZ_CP009483.1|WP_023371922.1|4872591_4873212_-|TetR/AcrR-family-transcriptional-regulator
MAAGVLTAKGRQTRQAIEQAARKLFAERGFHGTTLADITSAAGKSPAVFYRYFSDKEDLLAALAESFLHDVVAPSGLSVHLPDTPDDDTFFTSVVTGYWNIFKQNIGIMIAVAQLAATQRRFAAVQNEFRRFGMDIVAASVRRAQEQGYGAELHPQHTAAAIALLFENFTTVFVGRSGPENLRLDISDEDAIKTLSMIWKKTLYGT
>NZ_CP009483.1|WP_023371923.1|4873211_4874108_-|hydroxymethylglutaryl-CoA-lyase
MNQHVTIREVSLRDGLQIEKPIPLAAKLELLAAIAATGVREVEATAFVSPSKVPAMADAAELAAELHRYPDIEFSALVASPNGAKRAIAAGLRAIEYVVAASDSFSAANVGRSSAEATSQIGEILAIARGSGVIVEVIVATAWDCPFDGPTPSQRVLDIAAVARGLGVDRFSIADTIGTATPGRVSSLIAQLHPVIGDIALGGHFHNTRGAGLASAYAAVCSGVTRLDASVGGLGGCPFAPGATGNIATEDLVYLLADSGFEVHIDLPAAIAAAEVAKSVVGHDLPGALLRAGDRIRN
>NZ_CP009483.1|WP_023371924.1|4874104_4875313_-|CoA-transferase
MTAPTGPLDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEPPGAPDPLRTWGQAELNGHHVFWTVHARNKRAVTLDLRRPRGRELFLELVEKSDIAVENFRPGTLEKWNLGYDVLSERNPGIILVRVSGYGQTGPDAHKAGYASVAEAASGLRHLNGFPGGPPPRLALSLGDTLAGMFGAQGALAALYRRGVTGRGQVVDVALTESCLAVQESTIPDYDVGGVVRGPSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFARLCKAMGRPELVTDERFATHGARGRNQDELDAIIGAWAAERRPGEIIETLSAAGVIAGPINTVAEVVDDPQLRARGMLVEHYDERVERSVLGPGIVPVLSESPGRVRSAGPPHPGRHNDDVYIGLLGKTVEELTDLRAEGVL
>NZ_CP009483.1|WP_023371925.1|4875309_4876491_-|alpha/beta-hydrolase
MTTRHDYQRIPYLVAFQNNSGVRDVYGGLAEITVLESYLLRPSDKPSDTALVFMHPIGGGAYLPMINALARAGHHVIYCNSRFRGTDSGLLMEKVVEDLGECIKDAKARLGYQKVVLAGWSGGGSLSMFYQQQAQHATVTSSPSGDGPDLTRLDLPAADGIMLLAAHISRHGTLTEWLDASILDETDPTKRDPELDLYHPDNPNQPPYSQEFLARYRQAQIDRNRRITAWVKDKLAELAARGRPDDEFCFVVHGTMADPRWLDPTVDPNERTPGTCYLGDPRVVNMSPVGLARFCSLRSWLSQWSYDDARGDGVACARDLAVPALVIGNLADDACTPSHTRRLFDAIGNSDKEMYEIPGATHYYAGPNQRDKLAHAVDVVTDWLIRHDFASTR
>NZ_CP009483.1|WP_023371926.1|4876492_4877596_-|homogentisate-1,2-dioxygenase
MESFVHLRKGRTPRRLHADLDGLKDDELGRGGFTGRTANIYRRHDPTAYRAVGPLRPLDVLSDDLKPSDATDANGGPLLMFHNIDCRILLSRRHQAMPFYTRHVDGDLLCFVHRGSGMAETEFGPLRYREGDWVYIPKACTWRQIPDSETTLLMVEAADEFRVPAPGALGRHFPFDPSQITIPEPAPIDDDDRDQYEVRLIHRPLAEGVPTSLYYQHNPIDVEGWRGDNFPFTFNIGDYNVVTSNSVHLPPTVHLFMQATGVYVMNFLPKPAEGIPGTERTPWYHRNVDYDEIAFFHGGSLYGIPMPPGLISHAPQGVHHGAPEKARQRARRKFDEYSTVDWQVIAIDTRRRLTPCAEMLAHDLGQH
>NZ_CP009483.1|WP_023371927.1|4877948_4879874_+|PPE-family-protein
MEFLTLPPEVNSARILRGPGPAPLRAAATAWATLSEDLASSATAVSSVMSEISGSAWQGPAAAAMAAAVAPYPGWLGAAATRAAAAGRHAATAAAAYETARTATVPLEMLAQNRSRLVSLVAADVLGLNAPAIAATEAHYEQLWAQDVGAMAGYYAGASAAVAQLTPWQTLLSTLESPVGGMKAAEAAVSASSPSASTAATGVTLVIGGSGYPIPSQSYVNTVVADYVTPTFPGFTTANAQSLYTPAQSYWITGVKTLTEDASWAQGLTILDNAIHAQLATGNNVAVQGFSQGAGIASLEMANLKAEGVPTSSVSFSLIGDPMNPNGGLYSRFDGLTLASMGKSFPGSTPANDYPTVIYTIEYDGFADFPQYPLNLVADANAMLGALYVHPQYPVLTPAQVVTAVQLPTQGPTTTTYYMIPTQNLPLLEPLRALPLGNTVADLIQPDLKVIVNLGYGNPDYGYSTGPANVPTPFGLFPDASPGVVVADLIDGTRQGIGAAAADLGTWHAPAGNPAPNPFALSDLTPPTVAATTIDGIIQGLQTGNTNLTNAVTSATSSAYATLLPTADMLSAILVSLPSYDVNLFLDGVRQALDGDPAGIINAIGYPIAADTGLLTFLSFFLAYAYYGAAKSIAGDFASLI
>NZ_CP009483.1|WP_023371928.1|4879883_4880855_-|NADPH:quinone-oxidoreductase-family-protein
MRAIRVTRLEGPGAVEISEIDEPAGEGVVVDVYAAGAAFPDALLTRGLYQYRPEPPFVLGAEIAGVVRSAPQDAHVCAGDRVVGLTMLTGGMAEVAVLSPDRVFKLPDNVSFEAGAGLLFNDLTVYFALRVRGRLQRGETVLVHGAAGGIGTSALRLAPVLGASRTIAVVSTEEKAAIATAAGATDVVLAEGFKDAVKALTDGRGVDVVVDPVGGDRFTDSLRSLAPAGRLLVIGFTGGEIPTVKVNRLLLNNIDVVGVGWGAWAGKHPGALSEQWAALEQLLSSGELPPPEPVVYPLEQAAAAVASLENRTAKGKVVLRVRD

Crispr_ID: NZ_CP009483_19

• CRISPR_ID: NZ_CP009483_19
• CRISPR_location: 4933499-4933605
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_19

Consensus_repeat	Method
AACAGCCTGGCCATCGCTACCAGACATCCC	CRISPRCasFinder

spacers of NZ_CP009483_19

>19.1|4933529|47|NZ_CP009483|CRISPRCasFinder
ACCGCTCCGGAGGTTCTTCCTTATGTGAGCAGTGACCGCCTGAAGCG

CRISPR arrays and Neighbor proteins around NZ_CP009483_19

CRISPR arrays

The CRISPR arrays of NZ_CP009483_19

>merge|NZ_CP009483|19|4933499-4933605|CRISPRCasFinder
AACAGCCTGGCCATCGCTACCAGACATCCCACCGCTCCGGAGGTTCTTCCTTATGTGAGCAGTGACCGCCTGAAGCGAACAGCCTGGCCATCGCTACCAGACATCCC

>NZ_CP009483|19|16|4933499-4933605|CRISPRCasFinder
AACAGCCTGGCCATCGCTACCAGACATCCC	ACCGCTCCGGAGGTTCTTCCTTATGTGAGCAGTGACCGCCTGAAGCG
AACAGCCTGGCCATCGCTACCAGACATCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023371983.1|4939269_4939968_+|MspA-protein	unknown	unknown	gnl|CDD|370360
NZ_CP009483.1|WP_080674119.1|4928984_4929440_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP009483.1|WP_023371986.1|4942361_4943027_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP009483.1|WP_023371965.1|4923588_4923792_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_080674265.1|4933758_4934943_+|lipase	unknown	unknown	gnl|CDD|376422
NZ_CP009483.1|WP_036391809.1|4929484_4930174_+|cell-division-ATP-binding-protein-FtsE	unknown	unknown	gnl|CDD|225438
NZ_CP009483.1|WP_036391220.1|4927995_4928982_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NZ_CP009483.1|WP_023371968.1|4926878_4928009_+|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NZ_CP009483.1|WP_023371978.1|4935071_4935755_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023371979.1|4935795_4937583_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP009483.1|WP_023371988.1|4943270_4944077_+|spirocyclase,-AveC-family	unknown	unknown	gnl|CDD|379943
NZ_CP009483.1|WP_023371973.1|4931070_4931577_+|SsrA-binding-protein-SmpB	unknown	unknown	gnl|CDD|235455
NZ_CP009483.1|WP_023371982.1|4938746_4939022_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023371980.1|4937685_4938447_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|274729
NZ_CP009483.1|WP_036391816.1|4940230_4941865_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023371985.1|4941977_4942208_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023371972.1|4930174_4931068_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|225088
NZ_CP009483.1|WP_023371967.1|4925385_4926759_-|NADP-oxidoreductase	unknown	unknown	gnl|CDD|215457
NZ_CP009483.1|WP_023371974.1|4931684_4932530_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|274422
NZ_CP009483.1|WP_023371966.1|4923801_4925385_+|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023371983.1|4939269_4939968_+|MspA-protein	gnl|CDD|370360	pfam09203, MspA, MspA. MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel.	2.73135e-47
NZ_CP009483.1|WP_080674119.1|4928984_4929440_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.39515e-06
NZ_CP009483.1|WP_080674265.1|4933758_4934943_+|lipase	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.7373e-28
NZ_CP009483.1|WP_036391809.1|4929484_4930174_+|cell-division-ATP-binding-protein-FtsE	gnl|CDD|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	2.58522e-135
NZ_CP009483.1|WP_036391220.1|4927995_4928982_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	2.96996e-40
NZ_CP009483.1|WP_023371968.1|4926878_4928009_+|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP009483.1|WP_023371986.1|4942361_4943027_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.70851e-15
NZ_CP009483.1|WP_023371979.1|4935795_4937583_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.93177e-96
NZ_CP009483.1|WP_023371988.1|4943270_4944077_+|spirocyclase,-AveC-family	gnl|CDD|379943	pfam17198, AveC_like, Spirocyclase AveC-like. AveC catalyzes the stereospecific spiroketalization of a dihydroxy-ketone polyketide intermediate in the biosynthetic pathway of Avermectin, a potent antiparasitic agent. Additionally, it has a unique dehydration activity that serves to determine the regiospecific saturation pattern for spiroketal diversity. MeiC, the counterpart in the biosynthesis of AVE-like meilingmycin, also has spirocyclase activity, but lacks the dehydratase activity.	1.75548e-85
NZ_CP009483.1|WP_023371973.1|4931070_4931577_+|SsrA-binding-protein-SmpB	gnl|CDD|235455	PRK05422, smpB, SsrA-binding protein SmpB.	3.05424e-86
NZ_CP009483.1|WP_023371980.1|4937685_4938447_-|alpha/beta-hydrolase	gnl|CDD|274729	TIGR03695, menH_SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. This protein catalyzes the formation of SHCHC, or (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, by elmination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Note that SHCHC synthase activity previously was attributed to MenD, which in fact is SEPHCHC synthase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	3.47093e-33
NZ_CP009483.1|WP_036391816.1|4940230_4941865_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.31367e-61
NZ_CP009483.1|WP_023371972.1|4930174_4931068_+|ABC-transporter-permease	gnl|CDD|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	1.90971e-87
NZ_CP009483.1|WP_023371967.1|4925385_4926759_-|NADP-oxidoreductase	gnl|CDD|215457	PLN02852, PLN02852, ferredoxin-NADP+ reductase.	4.26634e-154
NZ_CP009483.1|WP_023371974.1|4931684_4932530_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	2.78315e-29
NZ_CP009483.1|WP_023371966.1|4923801_4925385_+|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	8.04027e-69

Protein sequences

>NZ_CP009483.1|WP_023371974.1|4931684_4932530_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MADRPLTQLDKSDVLAGLFAVWDSLDALLDGLPEADWQSASPLPGWNVKAVVSHIIGTESFLLGIGAPEADVDLSTLEHVRNPIGVMNESWVIHLSAESGASLLKRFREVTNKRRKALESMSDDDWNAATTTPAGPDTYGRFMRIRTFDCWMHEQDIRQAVQRPSSDDELGGRAGELSLDEMSSSMGFVVGKLAKAPDGSRVLFELTGPLARTMRVSVDGRAQVVDDFGGQEPTATIRMDGLQFTRLAGGRPMSPARSQDVELGGDEDLAGQIVKRLNFVI
>NZ_CP009483.1|WP_023371973.1|4931070_4931577_+|SsrA-binding-protein-SmpB
MAGQSKQAKAAGKKIGRKIIATNRKARHNYSIIEVFEAGMALQGTEVKSLREGHASLVDAFATIDDGEIWLRNLHIPEYQHGSWTNHEPRRNRKLLLHRRQIDTLIGKLREGNFALVPLSLYFTEGKVKVEIALARGKHAHDKRQDLARRDAQREVIRELGRRAKGMG
>NZ_CP009483.1|WP_023371972.1|4930174_4931068_+|ABC-transporter-permease
MRFGFLLNEVLTGLRRNVTMTIAMILTTAISIGLFGGGLLVVRLADNSRAIYLDRVETQVFLTDDVSANDPACDSDPCKALREKIEKRSDVKAVRFLNRQQAYDDAIRKFPQYKDVAGKDSFPASFIVKLENPEQHKDFDTAMQGQPGVLSVLNQKDLIDRLFAVLDGLSNAAFAVALVQAIGAVLLIANMVQVAAYTRRTEIGIMRLVGASRWYTQLPFLVEAMLAATVGVLIAIGGLIVVRAMFLENALNQFYQANLIARVDYADILYIAPWLLLLGVAMAGLTAYATLRIYVRR
>NZ_CP009483.1|WP_036391809.1|4929484_4930174_+|cell-division-ATP-binding-protein-FtsE
MITLDHVTKQYKSSARPALDDVNVKIDKGEFVFLIGPSGSGKSTFMRLLLAAETPTSGDVRVSKFHVNKLRGRNVPKLRQVIGCVFQDFRLLQQKTVYENVAFALEVIGKRTDAINRVVPEVLETVGLSGKANRLPDELSGGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDIMDLLERINRTGTTVVMATHDHHIVDSMRQRVVELSLGRLVRDEQRGVYGMDR
>NZ_CP009483.1|WP_080674119.1|4928984_4929440_+|hypothetical-protein
MNFWPNVLGKRDGNGARRTPSHLFGGRVRTSTVVLIVVFLAVWWTYDTYRPEPAPARPAQVVPPGFVPDPDYTWVPRERVQPPGTTSLRPTPTTVPTTEPTTTTTTPTPPPGSPPCLLPPPFCPASTTPSTPEPSPQPGPGPSPSSTPPAS
>NZ_CP009483.1|WP_036391220.1|4927995_4928982_+|mechanosensitive-ion-channel-family-protein
MTATNTTIRALSVAQRWHDFWRGHIGEWIITRGLRVVMLLIAAVLAARFVSWVAQRVTRRLDLGFAESDALVRSEATKHRQAVASVISWVSIVLIGIVVVMQIADVLQFSVGGLVAPATVVGAALGFGAQQLVRDLLAGFFIIVERQYGFGDLVKLTIMGSATDATGTVENVTLRVTRLRSADGEVFTVPNGQIVKSVNLSKDWARAVVDIPVSTNADLNRVNEVLHQECEHARDDAVLGELLLDSPTVMGVESIELDTVTLRLVARTLPGKQFEAGRQLRVLVIRALARAGIVTAADATVGLVEDPAVPAAEAAEAAEPSEVKGAVR
>NZ_CP009483.1|WP_023371968.1|4926878_4928009_+|peptide-chain-release-factor-2
MEPDRQADRRAEIAALDSTLTTVERVLDVDALRAKIDKLEHEASDPKLWDDQARAQRVTSELSHAQGELRRVEQLRSRLDDLPVLYELAAEEEGEAAAEALAEADAELKALHAEIEATEVRTLLSGEYDEREALVTIRSGAGGVDAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAYGTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVAAMRVLQAKLLERKRLEERAELDALKGEGGSSWGNQMRSYVLHPYQMVKDLRTEYEVGNPAAVLDGDIDGFLEAGIRWRNRKDDSN
>NZ_CP009483.1|WP_023371967.1|4925385_4926759_-|NADP-oxidoreductase
MRPHHRPYHVAIVGSGPSGFFAAASLLKAADGSDHIDVAVDMLEMLPTPWGLVRSGVAPDHPKIKSISKTFEKTAEDPRFRFFGNILVGEHVSPVELAERYDAVVYAVGAQSDKPLNIPGEDLPGSIAAVDFVGWYNAHPNFEHAAPDLSGARAVVVGNGNVAIDVARILVTDPEVLACTDIADHALESLRPCGVREVVLVGRRGPLQAAFTTLELRELGELEGVDVVVDPAQLAGISDEDAAAAGKTAKQNIKVLRDYAQRAPREGHRRIVFRFMTSPIEIRGDGRVEQIVLGRNELVADESGWVSARDTGEREELPAQLVVRSVGYRGVPTPGLPFDEKRGTIPNTAGRVEGSRNEYVVGWIKRGPTGVIGTNKKDSQDTVDTLIADLAATEALTEFPPDHGEQLAAWLASRQPQLVTTAQWKIIDRFERAAGEPHGRPRVKLPNLAELLRVGHG
>NZ_CP009483.1|WP_023371966.1|4923801_4925385_+|FAD-binding-oxidoreductase
MRSWWGWGDVEEALSDGETQALAARVATLLPGHDLTDHQPPDPGALGLAPPRITAPTSLAGLCSADFLDRAGHARGKAFRDVARNLQGRLDHVPDLIVRPRTERDVVDVLDWCTRERISVIPYGGGSSVVGGVEPRFDEPAVTLDLGALDAVLDIDRVSRAARIQAGALGPSIENQLRPYDLTLRHFPQSFGYSTLGGWLATRSGGHFATLYTHIDDLTASMRVVTAAGISESRRLPGSGAGPSPDRLFLGSEGTLGIITEAWMRLQDRPRWQLTASVAFDEWAAAVTATRTIAQAGLYPANCRLLDPAEAFLNAGTTVGGGLLVLAFESADHPVDAWLQRALDIAADHGGTVTARRGRENISDPTQNDASTNWRSAFLRMPYQRDALARRGVIAETFETACTWAGFDTLHAAVTDAARSAIESVCGAGLVTCRFTHVYPDGPAPYYGIYAAGRWGSLDAQWDDIKAAVSEAISTAGGTITHHHAVGRDHRPWYDRQRPDPFAAALRAAKSALDPAGILNPGVLVDF
>NZ_CP009483.1|WP_023371965.1|4923588_4923792_+|hypothetical-protein
MAGKEIDRVRATSALAVIKQHPGMVLFALSPVLALLAVIWWLAGTGWAIVTALVLLVVGGALVVVKR
>NZ_CP009483.1|WP_080674265.1|4933758_4934943_+|lipase
MSYVFAFPELMSGAATDVASIGSLVATANQGMAAATTAVVAAAEDEVSEAIAAIFSAHGEGYLALSAQAAAFHERFVQALAGAAGAYATAEAAGAAPLATFEQAVLGVQVEIQQIPTTIAAGFSSGLASLTSIPGNPLLMLLASDIPPLSWVLGNSPPPLLNLLLGQTVQYTTYQGMSVVQITPAAPTGEYVVALHGGAYILPASLFHWINYSVTAYQTGATFEVPIYPLLQQGGTAATVVPQTAGFISSLIAQHGAQNVSVVGDSAGGNLALGAVQYLVSQSEPVPSSMVLLSPWLDVGTGGLGAAWAGNLPANNYLVSPLYGSLDGLPPTYVYSGSLDPLAQQAAVLQHAALAQGAPMSFALEPGGIHDWVLLTPGGLLYWPQINQQLGIVA
>NZ_CP009483.1|WP_023371978.1|4935071_4935755_-|hypothetical-protein
MTYPHQFGVLQIVLAGVAVAAVVMLLSAVVGRRRTVHSSSAESAPRGRRLRFRPGRAAGGVVLLVVSILLLWFATLVQTYVGLTGEIKAAHVVATPVSNEAHRLNVDLTLYDDAGKAYAHQTYEVEGDMWVLQADIVELQHWVNILGMHSGYKVTRLFGQRLDGVSPTQHQIMLNGGDGDFFDDMRGGKWWTKPFVRAAYGNAVIAAPGAFDVYISQDAIKARASDG
>NZ_CP009483.1|WP_023371979.1|4935795_4937583_-|serine/threonine-protein-kinase
MPFDNGEVFAGYVIQRLLGTGGMGEVYLAQHPRLPRHDALKVLSLAATADQEFQARFKREAELAATLWHPHIVGVLDRGEFNGRLWISMEYVDGTDAGRLVRERYPHGMPEQDVAEIVTAVADALDFGHDRRLLHRDVKPENILVTAPDGHRRRVLLTDFGIARRIDDVSNLTDVNVAIGTISYVAPEQLLGKPLDGRADQYALAATTFYLLTGAPPFQDSNRAVVVSNHLNTPPPRISERRPELAHLDAVLARALAKDPNQRYPTCTAFALALTQHGPHRDAALAAGPAEDLRSGGRPATQRLERLVVQGIARAVAQSAVGAQSQVGILSFQVVPYEPLGNRRAPLPVEIQTDLVAGQLADGDEVEITGLWDGETLDADKIVNLSAGARPKRPRPEASATSPRDKSPKGRKLWIAALVAIVGVIVLTAAAVVYFTDSFGTRTRPGPIVKPVSATVFSPDGAPDNPQQASLAIDGNPNTAWSTVTYRDAVPFPKFIEGMGLLLHLAQPTALSEVTIDVSSTGTQVQIRSAPSQSPTKLADTTALTPNTPLQPGHNVIPVHDRAKTSNVLVWISTLGTTNGESRTSISEITLRAAG
>NZ_CP009483.1|WP_023371980.1|4937685_4938447_-|alpha/beta-hydrolase
MNRLQRDGVTLAVRVHNPLARGVPVLLTHGFGATAGMWEPNVDALSVDRPVIVWDQRGHGSSDAPDDIDAYSEQLSVADMAAILDAAGTDRAVLGGMSLGGYLSLAFHLVHPQRVAALVLVDTGPGYRNDEARAKWNAWVERRARQLERGGAPADVSPELTQAVHEHPEGLPRAARGVMAQKDARVITSLDSITVPTLVIVGAQDTDYLAAADYMARKIPTARKVVIENARHAANMDQPEAFNIAVREFLDHL
>NZ_CP009483.1|WP_023371982.1|4938746_4939022_-|hypothetical-protein
MPLQRFARAALAILMASGGIGLAALVGSSGVARADPDDDVTPQIIDDLLFTPIFAQDPRLLHPSSTAPTQDWGRIGMVCQNRNVKCQKNGF
>NZ_CP009483.1|WP_023371983.1|4939269_4939968_+|MspA-protein
MPISAVVRRAAVLALCLVVSVTAPSAGAQPDAEPPPGAAPPSDGSVPPGTPVRVNTPDGWVLALGGKDEKHVPVAPLTTALSSREYLSSGIFGASLTGPEPPRGVFEVGYEIGCGIDQSTSNGYVMANGSGISPSIAAELPLGPGQPPIVIPLASGQYNNVVSVGLKPGFVVIVPVVRKDFKGPSPWIMISDFHIKIDGCVGQSFIRSYATLTRITDESDVVLSYVGSTKAV
>NZ_CP009483.1|WP_036391816.1|4940230_4941865_+|PPE-family-protein
MWPPEVNSVLLLEGPGSGPMLEAAAAWDGIGTELSSAANAFGSITSDLGGQAWQGAASASMTTAASRYVDWLGRTAAQAEQSAAQARAAAIAYEAALAGIVHPELITANRGQLVSLVVANLFGQNAPAIAAAEAAYEQMWAQDVVAMGGYHSSASATVALLAPWEQALQNLPGLPGELAKAIGNGFALAEQEIQQTPTALAAAFTRVSDTVITGIFGSPANPPFPATEAGTFTGTPSLATRIEEAALWPVKPLLNLSGLETQISAPGSPLLALFASDIPPLSWFLGNSPPPFLNLLLGQTVQYTTYNGMSVVQITPAHPTGEYVVAIHGGAFIFPPSFLHWINYSVMAQQTGATVQVPIYPLLQQGGTAGTVVPTMAGFISTQIAQHQASNVSVIGDSAGGNLALAATQYLVDHGGPVPSSMVLVSPWLDVGMTNPNIALIQDPLLPVGPAQQIGKVWAGNLDVNDPLVSPLNGSLSGLPPTYVYSGNLDILAADVLVLQQAAATQGAPISFVLANGQIHDWILLTPDGFQYWPQINRELGIAA
>NZ_CP009483.1|WP_023371985.1|4941977_4942208_+|hypothetical-protein
MAVKSLTGFAGAVHEAVVAVLDAIVTAGDDRREHLEHAKRAIEKALHDSRSGAEWYLAEHLRQGIKDVEARTRDAA
>NZ_CP009483.1|WP_023371986.1|4942361_4943027_-|TetR/AcrR-family-transcriptional-regulator
MSQRLSPRKGPAAQAAVQPFRRPRGEPRRLLLDAARELFARQDYRSTTTREIAQAAGVSEYLLFRHFGSKAGLFREALVLPFTSFVDEFSRTWQSVVPEETDEEELARHFVEQLYDVLVDHRGLLLTLAASEAFGEEETEDTGIADMRRAIAVLGQISAEGMRLRGIRSSQPDLPAHSTVAMIVGMVALRSTFFGSVPPPREAIVDELVQAILHGFLHRRD
>NZ_CP009483.1|WP_023371988.1|4943270_4944077_+|spirocyclase,-AveC-family
MSTQLTPLLTAAVIFGWGSGIVFTATGGYLSVRRRRLHPLLLLCISAISFSWIEAPYDWAMYAQFPPALPRAPSWWPLNMTWGGLPSSVPVGYIGYFVLPAVIGATLGRRLSARFGWLAGNKRPITLLIVGLVVGFCWAFVFNAFVGARLGVFHYGYVIPGLAIFEGTKHQYPVYDSLALGVQMMVFTYLLGRTDSQGRNVIELWADKRSTSRLQSAVLSVVAVVVIGNLLYGAVFAPHLVTKLGGWVTAGPTEQLFPGVSNQPRQGG

Crispr_ID: NZ_CP009483_20

• CRISPR_ID: NZ_CP009483_20
• CRISPR_location: 5156747-5156834
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_20

Consensus_repeat	Method
CGCCCCCACAAGTGGGAGGTACCCC	CRISPRCasFinder

spacers of NZ_CP009483_20

>20.1|5156772|38|NZ_CP009483|CRISPRCasFinder
CACCCGCTTGCGGGCGACGAAGCGATGAGGCGGGGACG

CRISPR arrays and Neighbor proteins around NZ_CP009483_20

CRISPR arrays

The CRISPR arrays of NZ_CP009483_20

>merge|NZ_CP009483|20|5156747-5156834|CRISPRCasFinder
CGCCCCCACAAGTGGGAGGTACCCCCACCCGCTTGCGGGCGACGAAGCGATGAGGCGGGGACGCGCCCCCACAAGGGGGAGGTACCCC

>NZ_CP009483|20|17|5156747-5156834|CRISPRCasFinder
CGCCCCCACAAGTGGGAGGTACCCC	CACCCGCTTGCGGGCGACGAAGCGATGAGGCGGGGACG
CGCCCCCACAAGGGGGAGGTACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023372176.1|5152993_5153593_-|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl|CDD|179647
NZ_CP009483.1|WP_023372175.1|5151904_5152918_+|ketol-acid-reductoisomerase	unknown	unknown	gnl|CDD|235491
NZ_CP009483.1|WP_023372182.1|5159118_5160468_-|MFS-transporter	unknown	unknown	gnl|CDD|341028
NZ_CP009483.1|WP_023372177.1|5153589_5155020_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224154
NZ_CP009483.1|WP_042313923.1|5157869_5159027_-|MFS-transporter	unknown	unknown	gnl|CDD|341028
NZ_CP009483.1|WP_042313921.1|5146667_5147789_-|hypothetical-protein	unknown	unknown	gnl|CDD|225044
NZ_CP009483.1|WP_036391277.1|5163405_5164224_+|FAA-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
NZ_CP009483.1|WP_080674132.1|5162851_5163499_+|hypothetical-protein	unknown	unknown	gnl|CDD|283060
NZ_CP009483.1|WP_023372188.1|5166094_5166607_-|TIGR03618-family-F420-dependent-PPOX-class-oxidoreductase	unknown	unknown	gnl|CDD|274679
NZ_CP009483.1|WP_023372189.1|5166685_5167387_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP009483.1|WP_023372179.1|5155130_5156717_+|phosphoglycerate-dehydrogenase	unknown	unknown	gnl|CDD|237436
NZ_CP009483.1|WP_023372169.1|5145927_5146524_+|flavin-reductase-family-protein	unknown	unknown	gnl|CDD|376575
NZ_CP009483.1|WP_023372180.1|5156862_5157873_+|3-isopropylmalate-dehydrogenase	unknown	unknown	gnl|CDD|179579
NZ_CP009483.1|WP_036391914.1|5160522_5161212_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP009483.1|WP_023372173.1|5149520_5151365_+|acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|236098
NZ_CP009483.1|WP_080674133.1|5164220_5165708_+|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|234953
NZ_CP009483.1|WP_023372171.1|5147989_5148835_+|DoxX-family-protein	unknown	unknown	gnl|CDD|225168
NZ_CP009483.1|WP_023372174.1|5151364_5151883_+|acetolactate-synthase-small-subunit	unknown	unknown	gnl|CDD|183365
NZ_CP009483.1|WP_042312844.1|5148841_5149249_-|Low-molecular-weight-protein-antigen-6	unknown	unknown	gnl|CDD|371225
NZ_CP009483.1|WP_023372184.1|5161568_5162819_-|MFS-transporter	unknown	unknown	gnl|CDD|341028

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023372176.1|5152993_5153593_-|NAD(P)H:quinone-oxidoreductase	gnl|CDD|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	5.63477e-55
NZ_CP009483.1|WP_023372175.1|5151904_5152918_+|ketol-acid-reductoisomerase	gnl|CDD|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	0
NZ_CP009483.1|WP_023372182.1|5159118_5160468_-|MFS-transporter	gnl|CDD|341028	cd17475, MFS_MT3072_like, Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072 and similar transporters of the Major Facilitator Superfamily. This family includes the Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.93712e-97
NZ_CP009483.1|WP_023372177.1|5153589_5155020_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.37084e-78
NZ_CP009483.1|WP_042313923.1|5157869_5159027_-|MFS-transporter	gnl|CDD|341028	cd17475, MFS_MT3072_like, Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072 and similar transporters of the Major Facilitator Superfamily. This family includes the Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.5314e-77
NZ_CP009483.1|WP_042313921.1|5146667_5147789_-|hypothetical-protein	gnl|CDD|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	8.85692e-91
NZ_CP009483.1|WP_036391277.1|5163405_5164224_+|FAA-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	7.31847e-109
NZ_CP009483.1|WP_080674132.1|5162851_5163499_+|hypothetical-protein	gnl|CDD|283060	pfam05297, Herpes_LMP1, Herpesvirus latent membrane protein 1 (LMP1). This family consists of several latent membrane protein 1 or LMP1s mostly from Epstein-Barr virus. LMP1 of EBV is a 62-65 kDa plasma membrane protein possessing six membrane spanning regions, a short cytoplasmic N-terminus and a long cytoplasmic carboxy tail of 200 amino acids. EBV latent membrane protein 1 (LMP1) is essential for EBV-mediated transformation and has been associated with several cases of malignancies. EBV-like viruses in Cynomolgus monkeys (Macaca fascicularis) have been associated with high lymphoma rates in immunosuppressed monkeys.	1.07878e-07
NZ_CP009483.1|WP_023372188.1|5166094_5166607_-|TIGR03618-family-F420-dependent-PPOX-class-oxidoreductase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	9.57717e-34
NZ_CP009483.1|WP_023372189.1|5166685_5167387_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	8.50985e-55
NZ_CP009483.1|WP_023372179.1|5155130_5156717_+|phosphoglycerate-dehydrogenase	gnl|CDD|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0
NZ_CP009483.1|WP_023372169.1|5145927_5146524_+|flavin-reductase-family-protein	gnl|CDD|376575	pfam01613, Flavin_Reduct, Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. VlmR is a flavin reductase that functions in a two-component enzyme system to provide isobutylamine N-hydroxylase with reduced flavin and may be involved in the synthesis of valanimycin. SnaC is a flavin reductase that provides reduced flavin for the oxidation of pristinamycin IIB to pristinamycin IIA as catalyzed by SnaA, SnaB heterodimer. This flavin reductase region characterized by enzymes of the family is present in the C-terminus of potential FMN proteins from Synechocystis sp. suggesting it is a flavin reductase domain.	1.50107e-29
NZ_CP009483.1|WP_023372180.1|5156862_5157873_+|3-isopropylmalate-dehydrogenase	gnl|CDD|179579	PRK03437, PRK03437, 3-isopropylmalate dehydrogenase; Provisional.	0
NZ_CP009483.1|WP_036391914.1|5160522_5161212_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	6.95647e-18
NZ_CP009483.1|WP_023372173.1|5149520_5151365_+|acetolactate-synthase-large-subunit	gnl|CDD|236098	PRK07789, PRK07789, acetolactate synthase 1 catalytic subunit; Validated.	0
NZ_CP009483.1|WP_080674133.1|5164220_5165708_+|glutamate--tRNA-ligase	gnl|CDD|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP009483.1|WP_023372171.1|5147989_5148835_+|DoxX-family-protein	gnl|CDD|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	1.78642e-24
NZ_CP009483.1|WP_023372174.1|5151364_5151883_+|acetolactate-synthase-small-subunit	gnl|CDD|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	2.95825e-90
NZ_CP009483.1|WP_042312844.1|5148841_5149249_-|Low-molecular-weight-protein-antigen-6	gnl|CDD|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	6.81933e-17
NZ_CP009483.1|WP_023372184.1|5161568_5162819_-|MFS-transporter	gnl|CDD|341028	cd17475, MFS_MT3072_like, Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072 and similar transporters of the Major Facilitator Superfamily. This family includes the Mycobacterium tuberculosis uncharacterized MFS-type transporter MT3072. It belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19602e-78

Protein sequences

>NZ_CP009483.1|WP_023372179.1|5155130_5156717_+|phosphoglycerate-dehydrogenase
MNLPVVLIADKLAQSTVAALGDQVEVRWVDGPDRAKLLAAVPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHAIALLLAAARQIPAADATLRVRTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQRVAAFDAHVVAYDPYVSPARAAQLGIELLPLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAIGGGHVRAAGLDVFASEPCTDSPLFDLPQVVVTPHLGASTVEAQDRAGTDVAESVRLALAGEFVPDAVNVGAGVVSEEVAPWLDLVRKLGVLAAALSDGAPVSLSVQVRGELASEEVEVLRLSALRGLFSAVIDEPVTFVNAPALAAERGVSAEITKASESPNHRSVVDVRAVGADGSAVNVSGTLYGPQLTQKVVQINGRHFDMRAEGINLIVHYVDQPGALGKIGTLLGAAGVNIHAAQLSEDVEGPRATILLRLDQAVPDDVRSAMVAAVGANKIEVVDLS
>NZ_CP009483.1|WP_023372177.1|5153589_5155020_-|NAD(P)/FAD-dependent-oxidoreductase
MDVTVVGSGPNGLAAAVICARAGLKVNVIEAQPTFGGGARSAADVEFPGVLHDVCSAVHPLALASPFFAEFNLPARGVTLAVPEIAYANPLPGRPAAIAYHDLARTSTELDDGASWRRLLGPLVTNFAAVVDFMLGDKRSVPAALLPAMHLGLRMLAQGTPAWRSLAGEDSRALFTGVAAHAISRLPSLVSAGAGLMLATLAHSVGWPIPVGGSQVIADALIDDLRAHGGELTAGVEVTSPPGGVVVFDTAPTTLLHVYRDALPDRYAKALRRYRFGSGAAKVDFVLSDEIPWPDSRLSQAPTLHLGGTREQMARAEAEVAAGRHADWPMVLAASPHLADPGRVDGAGRRPFWTYAHVPSGSTVDATETVTRVVERLAPGFRDVVVAARSVPAARMVEHNANYVGGDISVGANSVWRAIAGPTPRLNPWRTPVPGVYLCSAATPPGPGVHGMSGYYAARTLLRHEFGITDMPKLSP
>NZ_CP009483.1|WP_023372176.1|5152993_5153593_-|NAD(P)H:quinone-oxidoreductase
MTKLAVIYYSATGHGTTMAQRIAAAAEAAGAEVRVRPVAETRDPASFAHNPAWTANYEATKDLPAATGEDIVWADAVIFGSPTRFGCVAAQLRNFLDSLGGLWAEGKLADKLYAAFTSSNTLHGGQETTLLTLYVTLMHFGGIIVPPGYTDPLKFVDGNPYGASLVSTHDNIHEFDEPTVNALDHLARRVVEVAGRLTS
>NZ_CP009483.1|WP_023372175.1|5151904_5152918_+|ketol-acid-reductoisomerase
MALEMFYDDDADLSIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKEGSKSRAKVEEQGLEVDTPAEVAKWADVIMLLAPDTAQAEIFSNDIEPNLKPGDALFFGHGLNIHFNLIKPPADVTVAMVAPKGPGHLVRRQFVDGKGVPCLIAVDQDPTGNGEALALSYAKAIGGTRAGVIKTTFKDETETDLFGEQAVLCGGTEELVKAGFDVMVEAGYPPEMAYFEVLHELKLIVDLMYEGGIARMNYSVSDTAEFGGYLSGPRVIDASTKDRMREILREIQDGTFVKKLVANVEGGNKELEQLRKENAEHPIEVTGKKLRDLMSWVDRPITETA
>NZ_CP009483.1|WP_023372174.1|5151364_5151883_+|acetolactate-synthase-small-subunit
MSSSSSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATEQKDMSRMTIVVACEETPLEQVTKQLNKLINVIKIIEQDEEQSVSRELALIKVRADAGTRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRGPRCIGTVK
>NZ_CP009483.1|WP_023372173.1|5149520_5151365_+|acetolactate-synthase-large-subunit
MSAPTKPHSPTSQGGENGAKPSLPQPRHVAPQQLTGAQAVIRSLEELDVDVIFGIPGGAVLPVYDPLFDSQKLRHVLVRHEQGAGHAASGYAHATGRVGVCMATSGPGATNLVTPLADAQMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKHNFLVRSGDEIPRVIAEAFHIAASGRPGAVLVDIPKDVLQGQCTFSWPPRMDLPGYKPNTKPHNRQIRAAAKLIAAARKPVLYVGGGVIRGEATQQLRELAELTGIPVVTTLMARGAFPDSHGQNLGMPGMHGTVAAVAALQRSDLLIALGTRFDDRVTGKLDSFAPEAKVIHADIDPAEIGKNRHADVPIVADVKAVIAELIAMLRHYDIPGTLELSEWWAYLEGVRKTYPLSYGPQSDGSLSPEYVIEKLGEIAGPDAVYVAGVGQHQMWAAQFIKYEKPRTWLNSGGLGTMGFAIPAAMGAKIALPDTEVWAIDGDGCFQMTNQELATCAIEGIPIKVALINNGNLGMVRQWQSLFYEERYSQTDLATHSHRIPDFVKLAEALGCVGLRCERAEDVVDVINQARAINDCPVVIDFIVGADAQVWPMVAAGTSNDEIQAARGIRPLFDDESEGHA
>NZ_CP009483.1|WP_042312844.1|5148841_5149249_-|Low-molecular-weight-protein-antigen-6
MACERWNDTRVVTGSPVVIRVSPIAHLAVGFATLGLLIPVLAWPPSAPLLLIPVLLSALIVRLRTVADDDGVTVRTLLGSRTVRWDDIDGLRFHRGSWARARLKDGTELRLPAVTFSTLPQLTEASSGRIPNPYR
>NZ_CP009483.1|WP_023372171.1|5147989_5148835_+|DoxX-family-protein
MTSSNDSHWQRPDGSPGPTAGRPVSASLVDPEDDLSPGGYSGDFGNTGTTTVIPPYDPANSGAVSSGYHLLDAQEPLPYAQPQPAGRPVPSAPAIDIDADDERVRAAGRRGTQHLGLLVLRVGLGAVLIAHGLQKLFGWWGGSGVTGFKNSLSDVGYQHADILAYVGAGGEIVAGVLLVLGLFTPLAAAGALAFLINGLLAMVSARPHSHFTYFLPDGNEYQISLVVMAVAVILSGPGRYGLDAGRGWAQRPFIGSFVALLAGIAAGIAVWVFLNGVNPLA
>NZ_CP009483.1|WP_042313921.1|5146667_5147789_-|hypothetical-protein
MRIRRSVRRALTVLCAAALVSSGCARFNDAQSQPFTTNPELRPQPSSTPPPPPPLPPTPFPKACPAPGVMQGCLESTSGLIMGIDSKTALVAERITGAVKEISISAEPKVKMVIPVDPAGDGGLMDIVLSPTYSQDRLMYAYISTPTDNRVIRIADGDVPKDILTGIPKGPAGNTGALIFTSPTTLVVMTGDAGNPAMAADPNSLAGKVLRIEQPTTIGQAPPTTALTGIGSGGGMCIDPVDGSLYVADRTPGADRLQRITKKSEVSTVWTWPDKPGVAGCAAMDGTVLVNLINTKLTVAVRLAPSTGAVTGEPDVVRKDTHAHAWALRMSPDGNVWGATVNKTAGDAEKLDDVVFPLFPQGGGFPRNNDDKT
>NZ_CP009483.1|WP_023372169.1|5145927_5146524_+|flavin-reductase-family-protein
MSKAVVAIHDVEVIDESFDDLMTMLDSPAFVVTTQADGHPSGCLVGFATQTSVQPPSFMIGMPRSNRTAEVAGRSDHVAVHLLAQHHRALAELFAGHTADDTDKFARCPWRAGPFGMPILDDAVAWFVGRTVSRSDVGDHVCYLLEPVSVWAPECSEELLYLSDIDDLDPGHEEPTRRFYEPTEVTRRYGVRFTLDVP
>NZ_CP009483.1|WP_023372180.1|5156862_5157873_+|3-isopropylmalate-dehydrogenase
MKLAIIAGDGIGPEVVAEAVKVLDAVLPGVQKTGYDLGASRFHATGELLPDTVLAELREHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSPLAGNPDIDFLVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGARRVVADAFERARRRRKHLTLVHKTNVLTFAGSLWWRTVQEIAKKYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHVGEDDAAGRVDRAVEKFLATRGNQRLTTTVIGDRIVAAL
>NZ_CP009483.1|WP_042313923.1|5157869_5159027_-|MFS-transporter
MLAVALVATLCATVFINGIAFLIPALNDVRGISLSEAALLSAMPSFGMVFTLIGWGYVLDLVGERIVLSVGLALTAAAAYGASLVPQSMLAEGIALFVGGMAAASANTASGRLVTGWFAAEQRGLAMGIRQTAQPLGIASAAVVLPELGERSISVALLFPATVCALAALLCAVWVRDPSRPARSVADHRELASPYRGTAVLWRIHLASALLMVPQTVVLTFMLVWLIHSHGWSIAAAGTLVSVSQLLGALGRIAAGRWSDHLGSRMRPIRMIAVAAALGMMLLAVADHLHSTVAVALMVVASVITVLDNGLAFTAIPEVAGRFWSGRAMGAQNTTQRLTAAVGPPVFGQVIEASGYPLAFAVCGLFPLLAWPIVPQHTRARVRTC
>NZ_CP009483.1|WP_023372182.1|5159118_5160468_-|MFS-transporter
MPRQPSDPGELSLFARWSIVVVSLLVTASSFLFINGVAFLIPRLEAARGTPLTQAGLLASMPSWGMVVTLVAWGYVLDRVGERLVMTVGSALTAAAAYAAASVHSLTLMGVYLFLGGMAAASCNSAGGRLVSGWFPPHQRGLAMGIRQTAQPLGIALGALVIPELAEQGAHAGLMFPAVACTVAAVASLIGVADAPRKSRKVATDEELASPYRGSSVLWRIHAVSALLMMPQTVTVTFMLVWLMNHHGWSVAAAGGLVTVSQLLGALGRIAVGRWSDYVGSRMRPVRIIAIAAASALFLLALTDNIGSRYDVLLMIAIAVIAVLDNGLEATAITEFAGPYWSGRALGTQNTTQRLMAAAGPPLFGALITTAAYPLAWALCGLFPLAAVPLVPTRLLPPGLETRARRQSVRRHRWRQAVRARELPTRPRLAGPPGSSRPGRRGRAPTPPT
>NZ_CP009483.1|WP_036391914.1|5160522_5161212_-|class-I-SAM-dependent-methyltransferase
MDWEAAYREHGVFGGPPPWNIGEPQPEIAALIRAGKIRSEVLDAGCGVAELSLALAALGHTVMGVDVSGTAIAKAKQAATDRGLSTVTFVQDDLTSLDGYDGRFNTIIDSTLFESLPVDSRDDYIRSVHRAAAPGASYYVLASTATALPADIELPPDAPAAPPNLVTETELREAVSRYWAIDEIRPAFIHVHLAEVLSRIPGVSLADYEVDERNRVKVSAFLLTAHKAG
>NZ_CP009483.1|WP_023372184.1|5161568_5162819_-|MFS-transporter
MATEPVSAALRWSMVAIALTVTASAFSFINAVPFMIPALEAARGTALAEAGLLSAMPSLGMVVTLIAWGYVADRIGERTVLATGSALTAVSAFAAASVNSLVAMGALLFLGGMAAASCNPACGRLVAGWFPAHQRGLAMGVRQTAQPLGIAMGALVIPRLAEHRPSLGLLFPASACAVSAVVGALIAHDPPRRTPPTASGTELVNPYRGNAVLWRIHMVSALMVMPQSMTVTFMLVWLTGNHGWSVRAAGALVTITQLLGALSRIAAGRWSDGVGSRMRPVRIVALATSVTLLMLSLANQLDSPLAVAFMVMVSVVTVMDNGLEATAITEFAGQFWSGRALGVQNTTQRLMTLAGPPAFGAMITVGGYPLAFALCGLFPLAAAPLVPVGLRPPDAEDREAEHSLGRLPRKPVQARD
>NZ_CP009483.1|WP_080674132.1|5162851_5163499_+|hypothetical-protein
MPAVVEQFPGDSWACVDQRSNRPGCTRPAAPGSRPSGSDDEGPQRPAAPGSRPSGSDDDGPQRPAAPGSRPSGSDDDGPQRPAAPGSRPSGSDDDGPQRPAAPGSRPSGSDDDGPQRPAAPGSRPSGSDDDGPQRPAAPGSRPSGSDDDGPQRPAAPGSRPSGSDDDGPQRPAAPGSRPSLGSSECALVESPVLTAHPADRPSSASKAHWTTPGG
>NZ_CP009483.1|WP_036391277.1|5163405_5164224_+|FAA-hydrolase-family-protein
MRLGRIASPDGPSGRSAFVSIEGSLDDPGGMTVREIAEHPFGTPTFTGRSWPLADVRLLAPILASKVVCVGKNYADHIAEMGGQTGPAQADPVIFLKPNTAIIGPNVPIRLPANASPVHFEGELAVVIGRPCKDVPAAQAADNILGYTVANDVSARDQQQSDGQWTRAKGHDTFCPVGPWIVTDLDPLDPTDLELRTEVNGEVKQHARTSLMIHDTGAIVEWISAVMTLLPGDLILTGTPAGVGPIEDGDTVSITVEGIGTLTNPIVRKGKS
>NZ_CP009483.1|WP_080674133.1|5164220_5165708_+|glutamate--tRNA-ligase
MTAAAPEEEATRVRVRFCPSPTGIPHVGMVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLNWDEGPEVGGPYGPYRQSQRREIYRDVIAQLLVADEAYYAFSTPEEVEARHIAAGRNPKLGYDNFDRHLTDSQRAAYLAEGRQPVVRLRMPDTDLSWSDLVRGPTTFAAGSVPDFALTRANGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALYQSLIRVGIAERVPEFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIADDRDLFSLDEMVAAFDVADVNSNPARFDQKKADALNAEHIRMLDVEDFTRRLRDYLDVHGHRIELDDAAFATAAELVQTRIVVLGDAWDLLKFLSDDQYAIDPKAAAKELGPDAAPVLDAAVAALQGVSDWIAAHIEEVLKAALIEGLELKPRKAFGPIRVAATGTTVSPPLFESLELLGRDRSLARLTSARDSVTK
>NZ_CP009483.1|WP_023372188.1|5166094_5166607_-|TIGR03618-family-F420-dependent-PPOX-class-oxidoreductase
MGSNQRAQIVMTEEEIADFVNKSRTGTLATIGPDGQPHLTAMWYAVVDGEIWLETKAKSQKAVNLKRDPRVSFLLEDGNTYDTLRGVSFEGVAEIIDEPDALFRVGVSVWERYTGPYSDELRPMVDQMMNKRVGVRIVSCRTRSWDHRKLGLPHMPVGGSTAPAVLGTGH
>NZ_CP009483.1|WP_023372189.1|5166685_5167387_-|IclR-family-transcriptional-regulator
MRQHSGIGVLDKAVGLLHAIAESPCGLAELCDRTGLPRATAYRLAAALEVHRLLGRDEEGRWRLGPAVSELAAHVNDSLLAASNAVLPKLRETTGESVQLYRREGTTRVCVAALEPAAGLRDTVPVGARLPMTAGSGAKVLLAYSDAAIQQAVLPNAKFGERVLAEVRRRGWAQSVAEREPGVASVSAPVRDRRGVVVAAISVSGPVDRMGRRPGARWAADLVAAAEEITGRL

Crispr_ID: NZ_CP009483_21

• CRISPR_ID: NZ_CP009483_21
• CRISPR_location: 5445903-5445989
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_21

Consensus_repeat	Method
CCGCGCCGGCCCGCATCGTCGCCCGGCTAGG	CRISPRCasFinder

spacers of NZ_CP009483_21

>21.1|5445934|25|NZ_CP009483|CRISPRCasFinder
TCTGATGGCCGGGCTCCTCACCGGG

CRISPR arrays and Neighbor proteins around NZ_CP009483_21

CRISPR arrays

The CRISPR arrays of NZ_CP009483_21

>merge|NZ_CP009483|21|5445903-5445989|CRISPRCasFinder
CCGCGCCGGCCCGCATCGTCGCCCGGCTAGGTCTGATGGCCGGGCTCCTCACCGGGCCGCGCCGGCCCGCATCGTCGCCCGGCTAGG

>NZ_CP009483|21|18|5445903-5445989|CRISPRCasFinder
CCGCGCCGGCCCGCATCGTCGCCCGGCTAGG	TCTGATGGCCGGGCTCCTCACCGGG
CCGCGCCGGCCCGCATCGTCGCCCGGCTAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023372419.1|5449526_5450570_+|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl|CDD|237061
NZ_CP009483.1|WP_036391352.1|5448233_5448770_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023372416.1|5447748_5448237_-|DUF4439-domain-containing-protein	unknown	unknown	gnl|CDD|373114
NZ_CP009483.1|WP_023372411.1|5439928_5441302_+|cobyrinate-a,c-diamide-synthase	unknown	unknown	gnl|CDD|234896
NZ_CP009483.1|WP_080674273.1|5450642_5450990_+|DUF448-domain-containing-protein	unknown	unknown	gnl|CDD|225350
NZ_CP009483.1|WP_036391350.1|5435471_5436956_+|malate-dehydrogenase-(quinone)	unknown	unknown	gnl|CDD|377591
NZ_CP009483.1|WP_023372408.1|5436952_5437423_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|225064
NZ_CP009483.1|WP_023372414.1|5444344_5445631_-|sterol-desaturase-family-protein	unknown	unknown	gnl|CDD|225546
NZ_CP009483.1|WP_023372415.1|5445999_5447748_+|proline--tRNA-ligase	unknown	unknown	gnl|CDD|236405
NZ_CP009483.1|WP_042312921.1|5451078_5453772_+|translation-initiation-factor-IF-2	unknown	unknown	gnl|CDD|235401
NZ_CP009483.1|WP_023372418.1|5448996_5449530_+|ribosome-maturation-factor-RimP	unknown	unknown	gnl|CDD|234627
NZ_CP009483.1|WP_023372412.1|5441481_5442717_+|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|381169
NZ_CP009483.1|WP_036444400.1|5455377_5456700_+|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240541
NZ_CP009483.1|WP_023372413.1|5442739_5444332_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP009483.1|WP_023372410.1|5439300_5439924_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl|CDD|235662
NZ_CP009483.1|WP_023372409.1|5437419_5439267_+|hypothetical-protein	unknown	unknown	gnl|CDD|274135
NZ_CP009483.1|WP_080674141.1|5454306_5455371_+|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA	unknown	unknown	gnl|CDD|223691
NZ_CP009483.1|WP_042313959.1|5433392_5435234_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NZ_CP009483.1|WP_023372405.1|5432804_5433212_+|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274925
NZ_CP009483.1|WP_023372422.1|5453885_5454383_+|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl|CDD|234787

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023372419.1|5449526_5450570_+|transcription-termination/antitermination-protein-NusA	gnl|CDD|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	0
NZ_CP009483.1|WP_042312921.1|5451078_5453772_+|translation-initiation-factor-IF-2	gnl|CDD|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NZ_CP009483.1|WP_023372416.1|5447748_5448237_-|DUF4439-domain-containing-protein	gnl|CDD|373114	pfam14530, DUF4439, Domain of unknown function (DUF4439). This domain has a ferritin-like fold.	4.0315e-36
NZ_CP009483.1|WP_023372411.1|5439928_5441302_+|cobyrinate-a,c-diamide-synthase	gnl|CDD|234896	PRK01077, PRK01077, cobyrinate a,c-diamide synthase.	0
NZ_CP009483.1|WP_080674273.1|5450642_5450990_+|DUF448-domain-containing-protein	gnl|CDD|225350	COG2740, COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription].	6.77167e-23
NZ_CP009483.1|WP_036391350.1|5435471_5436956_+|malate-dehydrogenase-(quinone)	gnl|CDD|377591	pfam06039, Mqo, Malate:quinone oxidoreductase (Mqo). This family consists of several bacterial Malate:quinone oxidoreductase (Mqo) proteins (EC:1.1.99.16). Mqo takes part in the citric acid cycle. It oxidizes L-malate to oxaloacetate and donates electrons to ubiquinone-1 and other artificial acceptors or, via the electron transfer chain, to oxygen. NAD is not an acceptor and the natural direct acceptor for the enzyme is most likely a quinone. The enzyme is therefore called malate:quinone oxidoreductase, abbreviated to Mqo. Mqo is a peripheral membrane protein and can be released from the membrane by addition of chelators.	0
NZ_CP009483.1|WP_023372408.1|5436952_5437423_+|GNAT-family-N-acetyltransferase	gnl|CDD|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	2.77483e-70
NZ_CP009483.1|WP_023372414.1|5444344_5445631_-|sterol-desaturase-family-protein	gnl|CDD|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	1.48494e-34
NZ_CP009483.1|WP_023372415.1|5445999_5447748_+|proline--tRNA-ligase	gnl|CDD|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NZ_CP009483.1|WP_023372418.1|5448996_5449530_+|ribosome-maturation-factor-RimP	gnl|CDD|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	7.08189e-48
NZ_CP009483.1|WP_023372412.1|5441481_5442717_+|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	1.84918e-101
NZ_CP009483.1|WP_036444400.1|5455377_5456700_+|MATE-family-efflux-transporter	gnl|CDD|240541	cd13136, MATE_DinF_like, DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	4.73532e-89
NZ_CP009483.1|WP_023372413.1|5442739_5444332_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	6.06232e-52
NZ_CP009483.1|WP_023372410.1|5439300_5439924_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl|CDD|235662	PRK05986, PRK05986, cob(I)yrinic acid a,c-diamide adenosyltransferase.	1.86067e-109
NZ_CP009483.1|WP_023372409.1|5437419_5439267_+|hypothetical-protein	gnl|CDD|274135	TIGR02442, Uncharacterized_protein_Rv2850c/MT2916, cobaltochelatase subunit. Cobaltochelatase is responsible for the insertion of cobalt into the corrin ring of coenzyme B12 during its biosynthesis. Two versions have been well described. CbiK/CbiX is a monomeric, anaerobic version which acts early in the biosynthesis (pfam06180). CobNST is a trimeric, ATP-dependent, aerobic version which acts late in the biosynthesis (TIGR02257/TIGR01650/TIGR01651). A number of genomes (actinobacteria, cyanobacteria, betaproteobacteria and pseudomonads) which apparently biosynthesize B12, encode a cobN gene but are demonstrably lacking cobS and cobT. These genomes do, however contain a homolog (modelled here) of the magnesium chelatase subunits BchI/BchD family. Aside from the cyanobacteria (which have a separate magnesium chelatase trimer), these species do not make chlorins, so do not have any use for a magnesium chelatase. Furthermore, in nearly all cases the members of this family are proximal to either CobN itself or other genes involved in cobalt transport or B12 biosynthesis.	0
NZ_CP009483.1|WP_080674141.1|5454306_5455371_+|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA	gnl|CDD|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	6.93942e-75
NZ_CP009483.1|WP_042313959.1|5433392_5435234_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.88213e-31
NZ_CP009483.1|WP_023372405.1|5432804_5433212_+|PPOX-class-F420-dependent-oxidoreductase	gnl|CDD|274925	TIGR04023, Pyridoxamine_5'-phosphate_oxidase, PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. This subfamily within the PPOX family occurs in at least 19 distinct species of F420 producers and is likely to bind F420 rather than FMN. The member OxyR was shown to use F420 to catalyze a C5a-C11a reduction in oxytetracycline biosynthesis. [Unknown function, Enzymes of unknown specificity].	1.04499e-56
NZ_CP009483.1|WP_023372422.1|5453885_5454383_+|30S-ribosome-binding-factor-RbfA	gnl|CDD|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	6.12872e-44

Protein sequences

>NZ_CP009483.1|WP_023372414.1|5444344_5445631_-|sterol-desaturase-family-protein
MNAALTRAEPEYRDGPVLAALGILYSAELIGLAGAAAFVTKGGHEHLDRGTTVLAVILVAAAAMAGWHAIRLLQGARVLKVTGLALQSALLITAIAIATVRPILGVPAVIVSAGVLVGWGRLARIGWRLAVADRPDLVASTATSASVGPAAARGSGGVSPGGIALVLVTSTLVLVALSMRGEMAVKLAILAIIFIPLERLFALRPLHVLRRGWRTDVVHYLVNGAARKVGLVGAVAVVGTVLQVLVPAAFRGNVAAASGWVQIVAALGITAVGGYAGHRAMHEVPVLWRFHRVHHSVREMDWLAAGHMHPLDQIAIRSAAVVPLYALGFGRVSLGAIVILLTVQDIFIHANLRMTCGPLRWLIATPQFHHWHHARQPQAYNTNYAAEFPIVDALFGTLYLPTGRWPAEYGIDDDQPDGYLRQLVWPLR
>NZ_CP009483.1|WP_023372413.1|5442739_5444332_+|MFS-transporter
MTALNDTERAAHNWTSGRQERPASARPARSAETASQRITRYYPTWLPSRRFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATMVIARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALRETNRERMKLDAAGAMLATLACTAAVFAFSMGPEKGWISVTTIGSGAVALAAVLAFIVVERTAENPVVPFHLFRDRNRLVTFIAIFLAGGVMFTLTVSIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGISSQLVSRFSPRVLTIAGGYLLVLAMLYGWLFMHRGVAYFPNLVVPIVVGGVGIGMAVVPLTLSAIAGVGFDQIGPVSAMTLMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLAALDHGYTYGLLWIAGAAVIVGGAAVLIGYTPAQVAHAQEVKEAIDAGEL
>NZ_CP009483.1|WP_023372412.1|5441481_5442717_+|uroporphyrinogen-III-C-methyltransferase
MTESPYLVGLRMAGKKVVVVGGGSVAQRRLPLLISSGADVHVITRSATRAVEAMEGITLSLREYRDGDLEGAWYAIAATDDAEVNATVVAEADSRQIFCVRADVAVEGSAVTPATFSYAGLSVGVLAGGEHRRSAAIRSAIREALQTGLITPESPEGPVSSDVVHGGVALVGGGPGDPELITVRGRRLLAHADVVIADRLAPPELLAELPPHVEVIDAAKIPYGRAMAQDAIHAAMIERAKSGSFVVRLKGGDPFVFARGYEEVLACADAGIPVTVVPGVTSAIAVPASAGVPVTHRATNHEFVVVSGHLPPGHPESLVNWNALAALSGTIVLLMAVERIELFVDALLKGGRPAKTPVLVVQQGTTPAQHTLRATLADTPEKVRAEGIRPPAIVVIGAVAGLGGVRGLNDS
>NZ_CP009483.1|WP_023372411.1|5439928_5441302_+|cobyrinate-a,c-diamide-synthase
MTSTPALVIAAPASGSGKTTVATGLMGALCQGGHRVAPFKVGPDFIDPGYHTLASRRVGRNLDPVLVGEQLIGPLYAHGTVGADIAVIEGVMGLFDGRIDEAVSGPAAGSTAHVAGLLGAPVVLVVDARGQSHSVAALLHGFTTFDSATRIAGVILNRVGTARHEHVLRQACEQAGVPVLGAIPRTAELELPTRYLGLVTAVEYGRRARLAVEAMTALVARHIDLSAIVAAAASRVGAPPWDPVTAVGGPVGGRPTVAMAAGKAFSFAYAEHAELLRAVGADVVEFDPLTQALPEGTNAVLLPGGFPEQFAAELSANELVRGQLQHMAAAGVPVHAECAGLIYLVSELDGYPMCGVLAGSARFTQRLTLGYRDAVAVADSPLYSVGRRVAGHEFHRTTVTFTDSYQPAWVYRSRGHDDHPLRDGVVHGGVHASYLHTHPAATPEAVARFVAHASARS
>NZ_CP009483.1|WP_023372410.1|5439300_5439924_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MPQGNPTYIPDDGLTTRARRNLPVLAIHTGDGKGKSTAAFGMALRAWNVGLDVAVFQFVKSAKWKVGEEAALHQLGRLHDEQGIGGAVEWHKMGAGWSWTRKSRKTGSEVDHAAAAADGWAEIARRLAEERHQFYVLDEFTYPLKWGWLDVDDVVEVLLARPGHQHVVITGRDAPPRLIEAADLVTEMTKVKHPMDVGRKGQQGIEW
>NZ_CP009483.1|WP_023372409.1|5437419_5439267_+|hypothetical-protein
MKPYPFSAIVGHDQMRLALLLCAVRPEIGGVLIRGEKGTAKSTAVRGLAALLSIVTGGGGAGLVEMPLGATEDRVVGSLDLQRVLREGEHAFSPGLLARAHGGVLYVDEVNLLHDHLVDILLDAAAMGRVHVERDGVSHSHDARFVLIGTMNPEEGELRPQLLDRFGLTVDVQASRDVDVRVEVIRQRMAYEADPDTFAERYASADAALANRIAAARGSVDDVLLPDNELRRIAALCAAFDVDGMRADLVVARTAAAHAAWRGAGVVEEQDIRVAAELALPHRRRRDPFDDHGLDRDQLNEALALGAPPAGGGAGSDPEPEPDPPGGGQSTNNSVFQSNSHAAPTPPKPSAPPSNMFRTRALTVPGVGEGAPGRRSRARNASGSVVAAAEAGAPAGHGLHLFATLLAAAEHASGAGPLRPQADDVRRAVREGREGNLVIFVVDASGSMAARDRLAAVSGATMSLLRDAYQRRDKVAVITFRQHEAGLLLPPTSSAHIAGRRLARFDTGGKTPLAEGLLAARELVIREKARDLARRALVVVLTDGRATSGPDPLGRSRIAASRLAAEGVAAVVVDCETSYVRLGLAGQLARQLGAPAVRLEQLHAEHLTRAVRNVA
>NZ_CP009483.1|WP_023372408.1|5436952_5437423_+|GNAT-family-N-acetyltransferase
MTEALRRVWAKDLDAAALYELLKLRVEVFVVEQACPYPELDGRDLLAETRHFWLENPDGEVICTLRLMEEHAGGEKTFRIGRLCTRRDARGQGHTTRLLRAALAEVGDYPCRIDAQVYLADMYAQHGFVRDGDDFIDDGIPHVPMLRPASGRTAHS
>NZ_CP009483.1|WP_036391350.1|5435471_5436956_+|malate-dehydrogenase-(quinone)
MSELTRTADVVLVGAGIMSATLAALLKRLEPDWSITVVERLDTVAAESSSPWNNAGTGHAALCELNYTPENFDGSINVSKAVRIAEQFQVTRQFWAYAVENAILGDVRSFLNPVPHVSFVHGADRVDYLRRRHAALASNPLFSAIELIDDPDEFVRRLPFMGAKRDFSEPVALNWASGGTDVDFGALSRQLIGFCVRNGATALFGHEVRQLSRQSDGSWTLTVTNRRAGQKHKLNAKFVFIGAGGDALPLLQKSGIREIKGFAGFPIGGRFLRTDNPVLTAAHRAKVYGVPSPGAPPLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKQGHFSDLPRSIKPNNVLSMLGVGFTQMTLLNYLVSQLRLSAPDRVDALREFAPSAVDSDWNLLVAGQRVQVIRRDKRKGGVLDFGTTIVGDADGSIVGLLGGSPGASTAVPIMLEVLERCFAHRYQSWLPTLKEMVPSLGARLSAEPALYNEVWSWTTKALQLDIP
>NZ_CP009483.1|WP_042313959.1|5433392_5435234_-|PE-family-protein
MLFVIATPEILTAASSDLAAVGSAVMAANTAAAVPTTRLLAAAQDEVSAAIAALFGAHAQEYQAISAQAAAFHDQFVRALTASGGSYAMAEAANASPFQTVLDAVNAPTQALLGRPLIGNGADGSAPGQAGAPGGLLYGNGGNGAAGGPNQAGGAGGNAGLIGHGGAGGVGGAGAVGGNGGPGGVLFGTGGAGGGGGPGVAGVNGGHAGQGGHGGNAYLFGDGGAGGQGGTGATGIAGSNPTPLGTAAPGSDGANQIMNTSSNLTGGAGEDGKAGGVTVAGGNGGNGGVARNVFGNGDVTGGAAGDGGNGAHGGNGGVGGEASTGGATAVSGSGGNGGNAEAAGGAGGNGGRGGFAQATSSVAGGNGGNGGNGHDTDVSGGAGGAGGVGGDVGRGGLVGGNGGGGGAGGVPGAWGGGGPPRGGGGGGGKADMGNSLGPNATVTAGDGGTGGDGGSALGTGGAGGAGGLGGHGGAGGLLFGNGGAGGAGGIGGAGGGGGAGGGGGAGGAGGGAIPGDVNTNSFGGDGGNGGSGGNGGSGGGGGAPGLGGTGGTGGWLIGQAGSTGAGGAGGAGGAGGAGGTAGDGGPAGGGGTSDGKAGLSGVDGFNGNTGQHG
>NZ_CP009483.1|WP_023372405.1|5432804_5433212_+|PPOX-class-F420-dependent-oxidoreductase
MTVFTDVEIEYLASQRLGRLATLAPKGSPQVRPVRFQYNAELDTIDIGGRAMAGSRKLRNVENDPRVSFVIDDLASIDPWRPRGIEIRGRAEALPVDGAQEGSGGALIRIHPRRIVVWGLDSESPALHARNVTKD
>NZ_CP009483.1|WP_023372415.1|5445999_5447748_+|proline--tRNA-ligase
MITRMSQLFLRTLRDDPADAEVPSHKLLIRAGYVRPIAPGLYSWLPLGLRVLRNIERVVREEMNAIGGQEILFPALLPRAPYETTNRWTEYGDSVFRLQDRRGNDYLLGPTHEELFTLTVKGEYNSYKDFPLVLYQIQNKYRDEARPRAGILRVREFVMKDSYSFDIDSAGLKAAYHAHREAYQRIFERLRVRYVIVSAVSGAMGGSASEEFLAESPVGEDTFVRCPESGYAANVEAVITARPETRPIDGQPEAVVHDTGDTPTIATLVEWANQADLGRTVTAADTLKNVLVKVRQPGKDWELLAIGVPGDREVDDKRLSAALEPAEYALLDDNDFARYPFLVKGYIGPKALHANNIRYLVDPRVVDGSSWITGADEPGRHVVGLVAGRDFTADGTIEAAEVREGDPSPDGAGSLVMARGIEIGHIFQLGQKYTDAFSADVLGEDGKPVRLTMGSYGIGVSRLVAVVAEQHHDELGLRWPPAIAPFDVHLVIANKDAEARTGAVALATELNQQGVEVLLDDRQASPGVKFKDAELLGMPWIVVVGRGWADGVVELRDRFSGQTRELAAGASLATDIAAVISG
>NZ_CP009483.1|WP_023372416.1|5447748_5448237_-|DUF4439-domain-containing-protein
MTSSEPSFGASPKRSPAGKDADTAALSDALAVEHATIYGYGIVSALSPPSVNDLVVEALNQHRQRRDDVIAMLAARKVTAPAAAPGYQLPNDVGSAADAARLAARMENDGATAWRAVVEHAETADDRAFASTALTQSAVMAARWNKVLGAWPITASFPGGNE
>NZ_CP009483.1|WP_036391352.1|5448233_5448770_-|hypothetical-protein
MPRAVPVVNRRGVLAGGAALAALGVVVSACGESTPKPPAVDELLAPLEQARRDSALASAAAAAIGNPPQIAAALTVVASQRGAHARALATEIARAAGKLVSATSETSSSSASPSPTDTEPPPPPPPVSDVVDSLRKSAEDASRLVATVSGYRAGLLASIAASCTASYTVALMPGGPSI
>NZ_CP009483.1|WP_023372418.1|5448996_5449530_+|ribosome-maturation-factor-RimP
MTTGLPSQTQVIELLGGAFACAGYEIEDVVIDTRAHPPRITVVADGDTALDLDTIAALSRSASALLDGLDAIRDKYVLEVSSPGVERPLTSEKHFRRARGRKIELTLADGSRLTGRVGELTGDTLALVIRQGRNWAVRQIPLAQVLKAVVQVEFSPPARAELELATAAGATGTEAES
>NZ_CP009483.1|WP_023372419.1|5449526_5450570_+|transcription-termination/antitermination-protein-NusA
MNIDMAALHAIEVDRGISVNELLETIKSALLSAYRHTQGHQTDARIEIDRKSGVVRVIARELDDEGNLISEWDDTPEGFGRIAATTARQVMLQRFRDAENERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRMGSETKASEGVIPAAEQVPGESYEHGNRLRCYVVGVSRGAREPLITLSRTHPNLVRKLFSLEVPEIADGSVEIVAVAREAGHRSKIAVRSNVPGLNAKGACIGPMGQRVRNVMSELSGEKIDIIDYDEDPARFVANALSPAKVVSVSVIDQNARAARVVVPDFQLSLAIGKEGQNARLAARLTGWRIDIRGDSPAHPAGQPEQGASRGMAHDR
>NZ_CP009483.1|WP_080674273.1|5450642_5450990_+|DUF448-domain-containing-protein
MIQREPSVAAHRCSDSPSGPVRTCVGCRKRELAVELLRVVAESTGNGNYAVIVDPSRRLQGRGAWLHPEPRCLQQAIRRRAFTRALRITGSPDTSAVVEHISGFSTEQQNRQQRT
>NZ_CP009483.1|WP_042312921.1|5451078_5453772_+|translation-initiation-factor-IF-2
MAGKARVHELAKELGVTSKEVLARLSEQGEFVKSASSTVEAPVARRLRESFGGAKPAPEQAPAKGPEKGPDRAAAKATAAAPGTDGGKAADQSLDQALDKAIAKAAGNGAPTAVAPDRAADSGKTATCPGPAPKPAVRTPRVGNNPPSSAQPAERPIPRPPAPRPGAPRPGAPRPGASPGSMPPRPGGAAGGPRPPRTGAPRPGGGRPGGPGGRSDGGGGNYRGGGAGVGAAPGTGFRGRPGGGGGGPGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLESFDLSYGEDTGDEADLQTRPPVVTVMGHVDHGKTRLLDTIRKANVREGEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRAQLTEYGLVAEDFGGDTMFVDISAKNGTNIEQLLEAVLLTADAALDLRANPDMEAQGVAIEAHLDRGRGPVATVLVQRGTLRVGDSVVAGDAYGRVRRMVDEHGDDIEAALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNAMAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELANREGVEIRYYSVIYQAIDEIEAALRGMLKPIYEEVELGRAEIRALFRSSKVGLIAGCMITSGVVRRNAKARLLRDNIVVAENLSIQSLRREKDDVTEVREGFECGLTLGYSDIKEGDVIESYELVQKERS
>NZ_CP009483.1|WP_023372422.1|5453885_5454383_+|30S-ribosome-binding-factor-RbfA
MADPARARRLAKRITTIVASAIEYEIKDPGLAGVTITDAKVTADLHDATVYYTVMGPTLDDEPDYAAAAAALDRAKGVLRTKVGAGTGVRFTPTLTFTRDTTSDTVHRMEELLARARAADADLARVRQGAKPAGDADPYRDGGASGELSDRIEAGDTGDHDRSRD
>NZ_CP009483.1|WP_080674141.1|5454306_5455371_+|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA
MAGLPGNLAIGSRLGTPVTTTDRETELAEVPTCPGARVDALGAVEMLSAAASVAVIAHVHPDADAIGAGLALALVLDKCGKQVEVSFGAPATLPESLASLPGCHLLVNPDAMRRDVDLAVTVDVPSVRRLGGLSDLAGPGRDVLVIDHHASNDAFGTANFIDLSADSTTMMIADLLDAWGKPIETDVAQCIYAGLTTDTGSFRWASARGYRLAARLVEIGVDNAAVSRTLMDTHPFEWLPMLSRVLGSAQLVPGAVAGRGLVYVVVDNREFLRARQEEVESIVDIVRTTQQAEVAAVLKEVEPRQWSVSMRAKRDMDLTPVAARFGGGGHRLAAGYSTSGSIDDVVASLLAALG
>NZ_CP009483.1|WP_036444400.1|5455377_5456700_+|MATE-family-efflux-transporter
MSGAGRSRVPGRRIAALALPALGVLAAEPLYLLFDTAVVGRLGALSLAGLAIGSLVLGLVGSQATFLSYGTTARSARHFGAGDRAAAVVEGVQATWLAAGLGVATIVVVEAAAVPLVSAIAGSSAITEAALPWLRIAILGVPAILVSLAGNGWMRGVQDTMRPLRYVVAGFGLSALLCPLLVYGWLGMPRLGLSGSAVANLVGQWLAALLFGGALLAERVLLRVDWPVLRAQLVMARDLIVRGLAFQACFVSAAAVAARFGAAALAAHQVVLQLWGFLALVLDSLAIAAQALVGAALGAGDVSHAKSVAWRVTVFSLLAAGVLAAALGVGAPLLPSLFTHDRSVLAAIAVPWWFLVAQLPFAGIVFALDGVLLGAGDAAFMRTATVVSALIGFLPLTWLSLVYGWGLAGIWSGLATFVALRLLFVGWRTISGRWALTGAA

Crispr_ID: NZ_CP009483_22

• CRISPR_ID: NZ_CP009483_22
• CRISPR_location: 5907468-5907544
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP009483_22

Consensus_repeat	Method
GATCATGTGCGCCGCTCCTTCTCA	CRISPRCasFinder

spacers of NZ_CP009483_22

>22.1|5907492|29|NZ_CP009483|CRISPRCasFinder
CTGCTTCGCAGTGCATCGTCGCCGGCGCG

CRISPR arrays and Neighbor proteins around NZ_CP009483_22

CRISPR arrays

The CRISPR arrays of NZ_CP009483_22

>merge|NZ_CP009483|22|5907468-5907544|CRISPRCasFinder
GATCATGTGCGCCGCTCCTTCTCACTGCTTCGCAGTGCATCGTCGCCGGCGCGGATCATGTGCGCCGCTCCTTTTCA

>NZ_CP009483|22|19|5907468-5907544|CRISPRCasFinder
GATCATGTGCGCCGCTCCTTCTCA	CTGCTTCGCAGTGCATCGTCGCCGGCGCG
GATCATGTGCGCCGCTCCTTTTCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023373281.1|5910255_5912346_-|transketolase	unknown	unknown	gnl|CDD|223100
NZ_CP009483.1|WP_036391473.1|5900752_5900986_-|preprotein-translocase-subunit-SecG	unknown	unknown	gnl|CDD|235881
NZ_CP009483.1|WP_023373271.1|5905376_5905775_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023373267.1|5901055_5903875_+|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl|CDD|234570
NZ_CP009483.1|WP_023373296.1|5921056_5921392_-|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|274862
NZ_CP009483.1|WP_023373288.1|5917594_5918230_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023373263.1|5898292_5900656_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl|CDD|224446
NZ_CP009483.1|WP_042313021.1|5913801_5917515_+|trehalose-phosphatase	unknown	unknown	gnl|CDD|224471
NZ_CP009483.1|WP_042313013.1|5893037_5894246_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_042313018.1|5912690_5913623_+|protoheme-IX-farnesyltransferase	unknown	unknown	gnl|CDD|235293
NZ_CP009483.1|WP_023373261.1|5897799_5898306_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|224991
NZ_CP009483.1|WP_023373273.1|5905824_5906565_-|6-phosphogluconolactonase	unknown	unknown	gnl|CDD|376480
NZ_CP009483.1|WP_023373294.1|5920763_5921054_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023373279.1|5909122_5910241_-|transaldolase	unknown	unknown	gnl|CDD|235117
NZ_CP009483.1|WP_023373277.1|5907575_5909126_-|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|235579
NZ_CP009483.1|WP_080674157.1|5919825_5920767_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_023373257.1|5895300_5897007_+|FUSC-family-protein	unknown	unknown	gnl|CDD|130728
NZ_CP009483.1|WP_023373259.1|5897020_5897803_-|carbon-monoxide-dehydrogenase	unknown	unknown	gnl|CDD|224238
NZ_CP009483.1|WP_036391476.1|5903888_5905241_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NZ_CP009483.1|WP_080691584.1|5918226_5919849_-|hypothetical-protein	unknown	unknown	gnl|CDD|373990

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023373281.1|5910255_5912346_-|transketolase	gnl|CDD|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NZ_CP009483.1|WP_036391473.1|5900752_5900986_-|preprotein-translocase-subunit-SecG	gnl|CDD|235881	PRK06870, secG, preprotein translocase subunit SecG; Reviewed.	6.59866e-13
NZ_CP009483.1|WP_023373267.1|5901055_5903875_+|phosphoenolpyruvate-carboxylase	gnl|CDD|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NZ_CP009483.1|WP_023373257.1|5895300_5897007_+|FUSC-family-protein	gnl|CDD|130728	TIGR01667, Uncharacterized_protein_HI_1680, integral membrane protein, YccS/YhfK family. This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane.	9.05953e-14
NZ_CP009483.1|WP_023373296.1|5921056_5921392_-|WXG100-family-type-VII-secretion-target	gnl|CDD|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	1.56415e-10
NZ_CP009483.1|WP_023373263.1|5898292_5900656_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl|CDD|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	1.22267e-146
NZ_CP009483.1|WP_042313021.1|5913801_5917515_+|trehalose-phosphatase	gnl|CDD|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	0
NZ_CP009483.1|WP_042313013.1|5893037_5894246_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.21537e-55
NZ_CP009483.1|WP_042313018.1|5912690_5913623_+|protoheme-IX-farnesyltransferase	gnl|CDD|235293	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional.	4.73787e-137
NZ_CP009483.1|WP_023373261.1|5897799_5898306_-|(2Fe-2S)-binding-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	3.44607e-62
NZ_CP009483.1|WP_023373273.1|5905824_5906565_-|6-phosphogluconolactonase	gnl|CDD|376480	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.	6.27508e-94
NZ_CP009483.1|WP_023373279.1|5909122_5910241_-|transaldolase	gnl|CDD|235117	PRK03343, PRK03343, transaldolase; Validated.	0
NZ_CP009483.1|WP_023373277.1|5907575_5909126_-|glucose-6-phosphate-dehydrogenase	gnl|CDD|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NZ_CP009483.1|WP_023373259.1|5897020_5897803_-|carbon-monoxide-dehydrogenase	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	7.99752e-55
NZ_CP009483.1|WP_036391476.1|5903888_5905241_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.38056e-31
NZ_CP009483.1|WP_080691584.1|5918226_5919849_-|hypothetical-protein	gnl|CDD|373990	pfam15649, Tox-REase-7, Restriction endonuclease fold toxin 7. A predicted toxin of the restriction endonuclease fold present in bacterial polymorphic toxin systems. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 5, type 6, or type 7 secretion system.	3.2505e-17

Protein sequences

>NZ_CP009483.1|WP_023373273.1|5905824_5906565_-|6-phosphogluconolactonase
MNLDVQTFPDSENLVEAAGQRLIQAIDNAVAARGQALIVLTGGGNGIALLRYLGASGPRIDWSKIHLFWGDERYVSEEDDERNDKQARAALLDHVDIPPGQVHPMAASDGEFGTDLDAAALAYEQVLAANAALGERAPNFDVHLLGMGPEGHVNSLFPHTAAVRETTRLVVPVEDSPKPPPQRITLTLPAIQRSREVWLIVSGRAKAEAVAAAIGGADPVAVPAAGAVGRESTLWLLDEEAAAKLG
>NZ_CP009483.1|WP_023373271.1|5905376_5905775_-|hypothetical-protein
MTIMADRSVRSGPERSRIKTLTQAALNADKTVEQVEDVLEGLDKTMKELNSSLTALNTTVERLEGGLDHLEGTLSSLDDLAKRLIVLVEPIEAIVDRIDYIVSLGETVMSPLSVTEHAVRGVLDRLRNRAVR
>NZ_CP009483.1|WP_036391476.1|5903888_5905241_-|PE-family-protein
MAGVLVAPEILTATAADLAGIGSTLEAANRAAAASTSRVLAAGADEVSEAIADLLSGYARQYQALSTSMAGFHQQFVQTLASGGGSYAAAETTNAAPLQTLEQQVLAVINAPTQTLLGRPLIGTGADGAPGRNGGDGGLLWGDGGNGGAGTADHPTGGNGGNAGLIGNGGNGGAGYSPAGVTGAAGGAGGVGGRGGWLFGNGGAGGNGGAGASGISGPPHATAGPGGDGGNGGAGGAAGLWGTGGAGGTGGQAGTGGRGFVGPVNGDGGNGGDGGNGGLGGAGGWLYGDGGAGGNGGMGGNGGPGGFSVVTGQPGDSGNGGNGGTGAGGGPGGWLYGNGGTGGAGGNGGAGGLPVRTGAGGDGGIGGDGATGGRGGFLTGNGGSGGAGGSGGHGNGDGTDGAGGDGGDGGDAVFIGNGGNGGPGGAGEPDGNGGAGGAGGQLFGGSGSPG
>NZ_CP009483.1|WP_023373267.1|5901055_5903875_+|phosphoenolpyruvate-carboxylase
MGNAADLVSDAALEPIGDVHRTRLGREATEPMRADIRLLGSILGDTVREQNGDEIFELVERARVEAFRVRRSEIDRTEMARMFDGIDIHRALPVIRAFSHFALLANVAEDIHRERRRAGHIAAGEPPQDSSLAATYLKLEAAELDSVTVADALKGALVSPVITAHPTEIRRRTIFITQHRITELMRLHAEGHSETDDGRSIELELRRQVLTLWQTALIRLSRLQISDEIAVGLRLYRSAFFKVVPQVNAEVRGALRDRWPDAELLSEPILKPGSWIGGDRDGNPNVTAEVVRLATGSAAYTALSHYLAELDQLEQELSMSSRLLTVTTELTALAGGCRDNARDDEPYRRALRVIRARLSATGAEILDQQPQHQLDLGLPPYATPGELRADLDVIDASLRTHGSALLADDRLALLREAVHVFGFHLCGLDLRQNSDVHEEVVGELLAWAGVHPDYGSLPEDERVALLVGELSTRRPLIGGRAQISDQARGELDIVAAAARAVRTYGAEAVPNYVISMCRSVSDMLEAAILLKEAGLLDASGPQPYCPVGISPLFETIDDLRNGATILQATLDLPLYRGLVKARGDMQEVMLGYSDSNKDGGYLAANWAVYRAELALVETARKSGIRLRLFHGRGGTVGRGGGPSYQAILAQPPGAVSGSLRLTEQGEVIAAKYAEPQMARRNLESLLAATLESTLLDVEGLGDTAAPAYAVLEEVAALSQRAYAELVHETPGFVEYFMASTPVSEIGSLNIGSRPTSRKPTSSIADLRAIPWVLAWSQSRVMLPGWYGAGTAFERWIAAGPEGEADKLDVLHDLYQRWPFFRSVLSNMAQVLAKSDLGLAAHYAELVADESLRRRVFDKIADEHHRTITMYKRITGHDDLLVDNPALARSVFNRFPYLEPLNHLQVELLRRYRSGEDDELVQRGILLTMNGLASALRNSG
>NZ_CP009483.1|WP_036391473.1|5900752_5900986_-|preprotein-translocase-subunit-SecG
MELALQITLVITSVLVVLLVLLHRAKGGGLSTLFGGGVQSSLSGSTVVEKNLDRLTLFITGIWVVCIVGVGLLIKYR
>NZ_CP009483.1|WP_023373263.1|5898292_5900656_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MRFTHPSGHGPGHDVAAGVPGPLARSEHDLVRGTGKYVDALRFDGEAHGCLVRSPLPHARIRRIDSSRAASAPGVLTVLTGHDIAATIRPLGCVIGLRSDDGTPRVDADRAVLAVDRVRHVGDGVAFVVAETANQAATAAALVDVGYEPLPYRSDADSPELEVPIWADAPDDVCFTWRFGDAPACRALFASAHHVVRITLASPRLVPYPIEPRAAVGIYDEQTDAMTLLANTQGVHFVRNVLARAFDRDPRRLRVLTPAVGGGFGAKIYAYPEHALVLESARRLRRPVRWTATRSESFLSDTQGRGHITDAAIALDKDGRFLALSVRPTVDLGAYLSQLAPLTATGVGAPVQAGAYRFQAVEINVRAMFTNNVPVDAFRGAGRPEANYVLERLIDRAARELGFDPALLRARNLPATQTRPLTAATGLVIDGGRFLDNQIRCLDVADRAGFEARRRESAARGRLRGFGFANYLEANGGLQVAEAMSAGAFPVECATLTFSGDGCLDIVVGTQSSGQDHAVPLQRLAAERLGMDPRHITVREGDSSVAPLGAGTGGSKSLLTSTAALDQALSDAVQRGKQVLADKWGVDAEAVSFADGRFLADAGAGEWFSSSIGEVATHWPGALDGQSEVSLRNGSFANGCHACELEIDPETGCVTVLRYVAVDDFGRVINEGAVRGQVQGAVAHGIAQALLERAPGCEELMRIAAGGAAAYTPPTACEIPDVEWVDNGLPSTTNVLGAKGCGESGTAAAPPAVMNAVADALRDYPAAAGIQMPARPAVIWKAIHEER
>NZ_CP009483.1|WP_023373261.1|5897799_5898306_-|(2Fe-2S)-binding-protein
MKNVEPAGTVRFTVNGAPAEVNVAAHERLVDVLRGPLELTGAAIGCDTAVCGACTVLLDGRTVKSCTVLAVQAADTDVVTVEGLATPDSLHVLQAAFLRHGAVQCGYCTAGMLVAAVDLLTRYGASLDEAIIRDGICGNLCRCTGYRSIVSAIAEAAAEMAADDGSAR
>NZ_CP009483.1|WP_023373259.1|5897020_5897803_-|carbon-monoxide-dehydrogenase
MSTRGYHRPTTVGEAVRMLSSVGAVVLAGGQTLVPALTRTPGRSVTLVDLGAVAGLRDIIAGGAEVRIGAMATHTQVATDALVRQAIPSLALLASQIADPQVRNRATIGGSLAYNDPAGDYPAACVGLGATVITDRRRIPAEEFFTGAFSTALAESEVIVSLAFPKPPELLRAAYVRLPDRAARSALVGVTVAETQSAFRVAISGLASGPTRWPDAEAALAKRPHPDALRDIAGPPAGTDPYRAHVARTLTIRAVRSLTT
>NZ_CP009483.1|WP_023373257.1|5895300_5897007_+|FUSC-family-protein
MNHIAALGRSVIAALRPAKAPWVVGPAVWAMATAASIGGVGVLVGDLQVAGVAFLGAACAVGFLATGSYRARWRAMMAQACGGALGIGAGALAPDSAAGLVLMAAIAGTISGLVGGIGASATAFGMMLTVGVAFGQFGGSSLPWWQQVLWYLAGSAVATVALLAAWVFQRGAQERRAVAGVFDAAADLCAAIGAEDAGAARARLAAASAIARSTREHRQADLVALAAAALYARGTPVPDPVIEAIRQAGKQVRAGDPVSVILPERDDPGLLALADALRPAPVRPGAAVPATGRSWASVRAACSRDTVANGVRIGLCLAVATGITVAMHERTHSFWLPLTTAVIVRPEYASVFVRTVNRIFGTLIGALLTTAFLAVWPCGLPVVAATALALGFVVLSAPKLYGLSVVGITSAALLSQSIGQADPNAPAIRLVDTLIGAAVAVVFGYLLWPGARRLPGSARFSSALAAARRYLTEAVKPAGRRRRWQPTRDEAYRLAHQVRAGAEAAVLEPPPVSALAAQAIPAAMELEDVVDAITAISVAVDGGYDAATLIDDVAHRLARLDQSALALR
>NZ_CP009483.1|WP_042313013.1|5893037_5894246_-|PPE-family-protein
MFTDFAFLPPEVISTRMYSGPGSGSLQAAAEGWQQLSAELHASAQTYRSVVSDLIAWHWVGPSSAAMAAAATSYAEWLEATAIQTGQTARQAATAASAFDEAFAMTVPPSIVFANREQLLLLIATNFFGQNTSAIAALELAYAEMWVTNSSVMQDYSVTSAAATKLTPFASPQQATTPAGLPGQAAAVAQATAGAAADGGNWLGNLLEQIGMALLPFAPELTPFFLEAGELINAIPFPSIVADDFTFLDGVMAWYATVSSINNISSLGTGIIGAEKNLGILPSLAAPAAEVVPSELAPLVNSVKNVADAVAKGGPGIGEVTAAFRGAGSIGPMSVPPTWTAPAVTTVKTFQGTPLTTLPAGDAGGAGMPGMPGIAPAGTRRGGVVPRYGLTPRVMTRPLSGG
>NZ_CP009483.1|WP_023373277.1|5907575_5909126_-|glucose-6-phosphate-dehydrogenase
MSAARNSAATQWHNPLRDKLDKRLPRIAGSCGMVIFGVTGDLARKKVMPAIYDLANRGLLPPTFALVGFARRDWDTQDFGQVVYQAVKEHCRTPFRQENWDRLAEGFRFVPGSFDDEQAFARLAETLDKLDAERGTGGNHAFYLAIPPKAFPVVSEQLHKSGLARPQSGRWSRVVIEKPFGHDLDSARELNRAVNAVFPEESVFRIDHYLGKETVQNILALRFANQFWDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFKPSALQAEKIKVLSATRLAEPLDETSSRGQYTAGWQGGEKVVGLLDEEGFAEDSTTETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFKRAPHLPFDATMTDELGANALVIRVQPDEGMTLRFGSKVPGSAMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPVLDYWAAHGKPDPYEAGTWGPDSAFQMLHRTGREWRRP
>NZ_CP009483.1|WP_023373279.1|5909122_5910241_-|transaldolase
MSQNPNLAALSAVGVSVWLDDLSRDRLNSGNLQELIDTKCVVGVTTNPSIFQKALAEGDAYNGQIAELAERGADVDATVRTATTDDVRRACDVFAPVWEASDGLDGRVSIEVDPRLAHDTDKTIQQAVELWKIVDRPNLFIKIPATKAGLPAITAVLAEGISVNVTLIFSVERYREVVDAYLAGIEKAREAGQDLSKIHSVASFFVSRVDTEIDKRLEKLGSQDAVALRGQAGVANARLAYAAYQEVFGGGDRFRALKTHGARVQRPLWASTGVKNPDYADTLYVTELAAPDTVNTMPEPTLDAVADHGVIKGDTVSGTASDAQQVFDKLQAAGVDLDDVFVVLEDEGVAKFEAAWTELLKETQAQLDSVTK
>NZ_CP009483.1|WP_023373281.1|5910255_5912346_-|transketolase
MTTLEEISTLTQPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMVHDPSDTTWLGRDRFVLSCGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTRGVEITTGPLGQGLASAVGMAMASRYERGLFDPDAEPGTSPFDHHIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDHNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGGENVVGIEEAIANAKAVTDRPSFISLRTIIGYPAPNLMNTGKAHGAALGDDEVAAVKKVLGFDPDKTFEVREDVLTHTRGLVARGKEAHDRWQVEFDAWAQREPERKALLDRLTAEQLPDGWDDDLPHWEPGSKALATRAASGEVLSALGPKLPELWGGSADLAGSNNTTMKGADSFGPPSISTKDYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAALMDIDTIYVWTHDSIGLGEDGPTHQPIEHLAALRAIPQLSVVRPGDANETAYAWRTILARGNGSGPVGLILTRQGLPILEGTSAEGVARGGYVLGDDSDDEPDVVIIATGSELQLAVEAQKLLADKDIIARVVSMPCVEWFESQPPDYRDSVLPPSVSARVAVEAGVAQCWHKLVGDTGEIISIEHYGESADYKTLFREFGFTAQAVAAAAERALDN
>NZ_CP009483.1|WP_042313018.1|5912690_5913623_+|protoheme-IX-farnesyltransferase
MARRHYAPGTATSKKSRALATALAYLALTKPRVIELLLVTAIPAMLLADRGSVHPLVILNTLIGGMMAAGGANTLNCVADADIDKVMKRTARRPLARAAVPTRSALAFGLALTVVSVLWLWWTTNLLSGLLALATVAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTLAWPALAMFAIVFFWTPPHTWALAMRYKEDYQEAGVPMLPAVATERQVTRQILIYTWLTVLATLALTPATGWLYAAVAVVAGAWFLAMAHQLDAGVRAGEPVKPLRLFLQSNNYLALVFCALAVDSALGLPTLL
>NZ_CP009483.1|WP_042313021.1|5913801_5917515_+|trehalose-phosphatase
MKSFTIDPRRHDGVIFVLDTPAVSTRPEPDNSVMESTLALAHRLRQAGLVTALYSPAGHSIRVLEATGIAEPFTARVERAPAGAPELPTKRYCIGLLAAAGKLGVAAERSAVVAGDSGGGAAARECGFAYVVGLDQEGHPDELLHCGADVVVADLSDVMVRTGDECMSRRPNALDSYGQVIGMVSGRQPFVCVNYDSTLSEIVPDPDLATLVDGAAEALADLSMQCPVAMLSGRDLADIRNRVGLPGIWYAGSHGFDLMAPDGTRYQHDAAAAAVPVMASAATTLQEELGPTSGAHVEHTRFGVRVHYGKVAHEQVPDVIAAAHRQSRRHGLRLITGRGVVELRPDVDWDKGTALAWIRDHVIESGVESGPQPGRVLPIYIGGDLTDEDAFDAVRFSGIGVVVRHDRDGDRPTAASFTLTSPTEARDFVRRGARWLAYDRETRARGWTFTWEGYDPPNEKLREALCTVGNGYFATRGAAPESKAGQVHYPGTYAAGVYNRLDDLVAGTRTAHESLVNLPNWLPLTFRIGDGDWLDLDAVTLLSYRQTLDLRGAVLTRELTYRDDAGRTTSITQHRFVAMNQVHVAALQTTVVAQDWEGTIEIRSTLDGDVRNSGVERYRDLASNHLQGLEKVALSENSVLMSVETTQSKIPVALAARTSVWHGDAPAPATYRLLDEEFEIGHQIFADLKPGQPLTVEKIVTLVTGRDVATSHPSTGAERRLARQGRFAETCAAHRLAWAHLWERVSIEFSNHTEELRVLRLHLLHLLQTVSYNSEELDVGVPARGLHGEAYRGHIFWDELFIFPVLNLRVPTVTRSLLRYRHRRLVEARGAAKLAGYRGAMYPWQSGSDGREESPEQHLNPRSGRWRPDASHRAHHIGIAVAYNVWNFYQVTGDLAYMIDYGTEMMAEIARFWVSRATYDRDRDRYTINGVIGPDEFHSGYPDRPYDGVDNNAYTNVMAVWVILRAIDALQLMPLPNRLDLCEELGLTDEELAHWDHVSRRMFVPFHDGVISQFEGYEQLLELDWDAYRRRYRNIQRLDRILEAEDDDVNRYRASKQADVLMLLYLLSADELRELLDRLDYHLDPRRIPEMVDYYLARTSHGSTLSAVVHGWVLARANRDRALEFFQQVLKSDIADIQGGTTSEGVHLAAMAGSVDFVQRCFTGLEIRGDRIVLSPLWPEYLGALGFPIHYRGNHLHLRVSGKGAEISVEPRDVPPVEIECRGRVELLVPGSVVRFT
>NZ_CP009483.1|WP_023373288.1|5917594_5918230_-|hypothetical-protein
MNQKYGDDPATWPEYRRAMKHELNAAGIPEDTIFQLVNSRYDYPQAVPIMVDWLQNLDERIPAEEDRRAWRVALIRNLITKNAKGNRVAADILFHQFDIDPPLSGLELEVTGFALAEVCDGSDFPRVAALLRSGKDFSTKFELVRWLGRFKTEEAKELVVSQLADPTTRADAMAALVRQRATGVRVTVARYLNDEVWRKEAQKTLDKLPPD
>NZ_CP009483.1|WP_080691584.1|5918226_5919849_-|hypothetical-protein
MRHHVVRHVLGLDLVRPEDGERVLFLLTAQHGHLMVTAIADRQPGDRCDDFFQLLVVDAGRGVDGQVIGQWGQPLLSSEFTRNHRTPGCHTIDPLAREVGGAAMTDVDPELFYDAAAAYKENSDHAGAALRKLAGVDAAGAAGTHGVGPQWASSYDAAAEEAGQVAYRLVNVFHNLGSLLRQNGINHDQTEEASTLNQRDAYGAPITPPGESAGTFIDAAVAVSSVAGGGDPEPPHWNLVADRIVDGWPDGHPDHALAASAAWETFGHDLVRIDDQPGPEEQRLIVDVEAAEIAPLVDRLEEARGVNTDIAGACGDLSRAAKDYGNKLKSVKDDMAFVVNQLHWLIIILDSYPPVLHRLTGPIKETFIAAAVTQINGLNAALRTIATASMTDLTAAGSAMGAALPAVKRLLDLVPRRVNPTPTHRVNDNRRKGRRAEDIAGIDQSKKVRIPVRNPKPGRPRFRIPDEIDDENHVVREVKNVKKLDTTQQIRDIAEWARDNGYKLVIVVDKGRTDAGSVEQTLERDFEGLDVVIDDSKNLS
>NZ_CP009483.1|WP_080674157.1|5919825_5920767_+|hypothetical-protein
MPDDVVPHVLDPTTSWQIVIEGSDPAEVRPARRFAKALARAAGGVAVDEQTEEILGAKRARQIASPGSELIRIVDLQWHSPESAPDAATLWLELARKFLPEALPRRFGNVYPLRYRLDRDGDDQFIATFASHGAWFKATLPCIDGGLYLEPWDGILIDTLKMVAQPLDDPPWRNTVQRFFVEYARRRGSVLATGEVLRNHKLSGPPDTSWDLSGSLRGPGGILGLPANPVWWTWLGNDYLPLVRDYLPPEHTTYYDEGALYAPTEEPTDRGQLAGLPDPFPASLRVTAIPSEYGPSNTPMNSPAAIRPRLNQG
>NZ_CP009483.1|WP_023373294.1|5920763_5921054_-|hypothetical-protein
MARRTVNEHDLVDAADAMRQFCLVMKDRLNEVATELRGLQHHWEGVAFDAFLERVQHWQGWADEMSEVVFDMHLNAHIAHRNYVHNAEVNTAMWGG
>NZ_CP009483.1|WP_023373296.1|5921056_5921392_-|WXG100-family-type-VII-secretion-target
MVSMAAEELRVYCAELAHASKTTTGAADEIDGLRDKLGGQTDGLAGTWTGQAASAYLDVWAEIDDECGQMLADLRWIGESLAAAAAGYAQMEHAAADAFGSIRPAGPVDGR

Crispr_ID: NZ_CP009483_23

• CRISPR_ID: NZ_CP009483_23
• CRISPR_location: 6349449-6350417
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 13 spacers

Consensus repeat of NZ_CP009483_23

Consensus_repeat	Method
CAACATCGCCACCGTGGCCACCGC	CRISPRCasFinder

spacers of NZ_CP009483_23

>23.1|6349473|48|NZ_CP009483|CRISPRCasFinder
GTTGTTCAGCAACAACAACACGCTCTCGGCCAGCTCGTTCGGCGTGGA
>23.2|6349545|51|NZ_CP009483|CRISPRCasFinder
GATCGGTGACAACAACGGGGTCTCGGCCACCAATTCACTGGGTGTCGGCGG
>23.3|6349620|57|NZ_CP009483|CRISPRCasFinder
GATCGGTTTCGGCCAGGGCGACAATCAGGTTGCCGCCGAATCCGGTGCCGGGGGCGG
>23.4|6349701|48|NZ_CP009483|CRISPRCasFinder
GTTGTTCGGTGGCAACAACACAGTTTCGGCCAGCGGGCTGGGTGCAGG
>23.5|6349773|48|NZ_CP009483|CRISPRCasFinder
GCTGTTCAGCAGCCACAGCACCGCCCACGCCAGCGCGTTGGGCGTGGA
>23.6|6349845|48|NZ_CP009483|CRISPRCasFinder
CTTGGGTGACGGCAACAACGTCTCGGCCAGCGCGCCCGGCATCGGGGG
>23.7|6349917|51|NZ_CP009483|CRISPRCasFinder
TCTCGGCCAGGGCAACACCGCGGTTGAGGCCGTGGCCGGCCCCGGCGGCGC
>23.8|6349992|45|NZ_CP009483|CRISPRCasFinder
CTTGGGTGACGGCAACAGCGTCACGAACAAGGCGCTGGGCGCGAC
>23.9|6350061|45|NZ_CP009483|CRISPRCasFinder
CATCGGGGACAACAACACCGCAGACGTCAATGTGATCGGCGTGGA
>23.10|6350130|48|NZ_CP009483|CRISPRCasFinder
AATCGGTGACAACAACGGAATTTCCGCCGGCGCACCGGGACTGGGCGC
>23.11|6350202|51|NZ_CP009483|CRISPRCasFinder
CATCGGCAGCGACAACAGTCAGGTCAGCGCCGTGTCCGGCGCCGGAGGCGG
>23.12|6350277|45|NZ_CP009483|CRISPRCasFinder
GATCGGAGACAAGAACTCGGCTTCCGCCAGCGCGCTGGGCGCCGG
>23.13|6350346|48|NZ_CP009483|CRISPRCasFinder
GTTGTTCAGCAGCAACAACACGTCCTCGGCCAGCGCTCTCGGCATCGA

CRISPR arrays and Neighbor proteins around NZ_CP009483_23

CRISPR arrays

The CRISPR arrays of NZ_CP009483_23

>merge|NZ_CP009483|23|6349449-6350417|CRISPRCasFinder
CAATATCGCCAACGTGTCCACCGCGTTGTTCAGCAACAACAACACGCTCTCGGCCAGCTCGTTCGGCGTGGAGAACATCGCCACGGTGGCCACCTCGATCGGTGACAACAACGGGGTCTCGGCCACCAATTCACTGGGTGTCGGCGGCAATATCGCCACCGTCGCCACCGCGATCGGTTTCGGCCAGGGCGACAATCAGGTTGCCGCCGAATCCGGTGCCGGGGGCGGCAATATCGCCTCGGTGGCCACGGTGTTGTTCGGTGGCAACAACACAGTTTCGGCCAGCGGGCTGGGTGCAGGAAATATCGCCGACGTGGCGACCGTGCTGTTCAGCAGCCACAGCACCGCCCACGCCAGCGCGTTGGGCGTGGAGAATATCGCCACCGTGGCCACCTCCTTGGGTGACGGCAACAACGTCTCGGCCAGCGCGCCCGGCATCGGGGGCAACATCGCCACCGTGGCCACCGCTCTCGGCCAGGGCAACACCGCGGTTGAGGCCGTGGCCGGCCCCGGCGGCGCCAACATCGCCACCGTGGCGACCGCCTTGGGTGACGGCAACAGCGTCACGAACAAGGCGCTGGGCGCGACCAATATCGCCAGCGTCGCCACCGTCATCGGGGACAACAACACCGCAGACGTCAATGTGATCGGCGTGGAAAACATCGCCACCGTGGCTACGGCAATCGGTGACAACAACGGAATTTCCGCCGGCGCACCGGGACTGGGCGCCAATATCGCCACCGTCGCCACCGCCATCGGCAGCGACAACAGTCAGGTCAGCGCCGTGTCCGGCGCCGGAGGCGGCAATATCGCCTCGGTGGCCACCGTGATCGGAGACAAGAACTCGGCTTCCGCCAGCGCGCTGGGCGCCGGTAACATCGCCACGGTGTCGACCGTGTTGTTCAGCAGCAACAACACGTCCTCGGCCAGCGCTCTCGGCATCGAGAACATCGCCACGGTGGCGACCTC

>NZ_CP009483|23|20|6349449-6350417|CRISPRCasFinder
CAATATCGCCAACGTGTCCACCGC	GTTGTTCAGCAACAACAACACGCTCTCGGCCAGCTCGTTCGGCGTGGA
GAACATCGCCACGGTGGCCACCTC	GATCGGTGACAACAACGGGGTCTCGGCCACCAATTCACTGGGTGTCGGCGG
CAATATCGCCACCGTCGCCACCGC	GATCGGTTTCGGCCAGGGCGACAATCAGGTTGCCGCCGAATCCGGTGCCGGGGGCGG
CAATATCGCCTCGGTGGCCACGGT	GTTGTTCGGTGGCAACAACACAGTTTCGGCCAGCGGGCTGGGTGCAGG
AAATATCGCCGACGTGGCGACCGT	GCTGTTCAGCAGCCACAGCACCGCCCACGCCAGCGCGTTGGGCGTGGA
GAATATCGCCACCGTGGCCACCTC	CTTGGGTGACGGCAACAACGTCTCGGCCAGCGCGCCCGGCATCGGGGG
CAACATCGCCACCGTGGCCACCGC	TCTCGGCCAGGGCAACACCGCGGTTGAGGCCGTGGCCGGCCCCGGCGGCGC
CAACATCGCCACCGTGGCGACCGC	CTTGGGTGACGGCAACAGCGTCACGAACAAGGCGCTGGGCGCGAC
CAATATCGCCAGCGTCGCCACCGT	CATCGGGGACAACAACACCGCAGACGTCAATGTGATCGGCGTGGA
AAACATCGCCACCGTGGCTACGGC	AATCGGTGACAACAACGGAATTTCCGCCGGCGCACCGGGACTGGGCGC
CAATATCGCCACCGTCGCCACCGC	CATCGGCAGCGACAACAGTCAGGTCAGCGCCGTGTCCGGCGCCGGAGGCGG
CAATATCGCCTCGGTGGCCACCGT	GATCGGAGACAAGAACTCGGCTTCCGCCAGCGCGCTGGGCGCCGG
TAACATCGCCACGGTGTCGACCGT	GTTGTTCAGCAGCAACAACACGTCCTCGGCCAGCGCTCTCGGCATCGA
GAACATCGCCACGGTGGCGACCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009483.1|WP_023374013.1|6345789_6347283_+|DUF4185-domain-containing-protein	unknown	unknown	gnl|CDD|379383
NZ_CP009483.1|WP_023374024.1|6355627_6357004_-|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354
NZ_CP009483.1|WP_023374011.1|6344964_6345486_-|ATP-binding-protein	unknown	unknown	gnl|CDD|214643
NZ_CP009483.1|WP_042314102.1|6335160_6335901_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP009483.1|WP_042313105.1|6363578_6364922_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NZ_CP009483.1|WP_023374003.1|6338952_6340293_+|acetyltransferase	unknown	unknown	gnl|CDD|376607
NZ_CP009483.1|WP_036394268.1|6354332_6355610_+|divalent-metal-cation-transporter	unknown	unknown	gnl|CDD|334596
NZ_CP009483.1|WP_023374001.1|6337992_6338856_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|367049
NZ_CP009483.1|WP_023373999.1|6336033_6337857_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP009483.1|WP_023374028.1|6360069_6360339_-|DUF4242-domain-containing-protein	unknown	unknown	gnl|CDD|379428
NZ_CP009483.1|WP_023374019.1|6353345_6354182_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235975
NZ_CP009483.1|WP_023373995.1|6333541_6335092_+|MFS-transporter	unknown	unknown	gnl|CDD|365860
NZ_CP009483.1|WP_036394260.1|6365380_6365686_-|hypothetical-protein	unknown	unknown	gnl|CDD|227505
NZ_CP009483.1|WP_023374026.1|6357159_6360066_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|226415
NZ_CP009483.1|WP_023374005.1|6340259_6341756_-|potassium/proton-antiporter	unknown	unknown	gnl|CDD|235410
NZ_CP009483.1|WP_036394264.1|6362067_6363510_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP009483.1|WP_023374030.1|6360707_6361739_+|esterase	unknown	unknown	gnl|CDD|369561
NZ_CP009483.1|WP_023374009.1|6342697_6345031_+|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl|CDD|225094
NZ_CP009483.1|WP_023374007.1|6341909_6342614_+|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|223643
NZ_CP009483.1|WP_036394270.1|6352789_6353272_-|flavin-reductase-family-protein	unknown	unknown	gnl|CDD|224766

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP009483.1|WP_023374013.1|6345789_6347283_+|DUF4185-domain-containing-protein	gnl|CDD|379383	pfam13810, DUF4185, Domain of unknown function (DUF4185).	2.72381e-154
NZ_CP009483.1|WP_023374024.1|6355627_6357004_-|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.50209e-44
NZ_CP009483.1|WP_023374011.1|6344964_6345486_-|ATP-binding-protein	gnl|CDD|214643	smart00387, HATPase_c, Histidine kinase-like ATPases. Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.	4.24835e-07
NZ_CP009483.1|WP_042313105.1|6363578_6364922_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.28246e-54
NZ_CP009483.1|WP_023374003.1|6338952_6340293_+|acetyltransferase	gnl|CDD|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	1.21924e-08
NZ_CP009483.1|WP_036394268.1|6354332_6355610_+|divalent-metal-cation-transporter	gnl|CDD|334596	pfam01566, Nramp, Natural resistance-associated macrophage protein. The natural resistance-associated macrophage protein (NRAMP) family consists of Nramp1, Nramp2, and yeast proteins Smf1 and Smf2. The NRAMP family is a novel family of functional related proteins defined by a conserved hydrophobic core of ten transmembrane domains. This family of membrane proteins are divalent cation transporters. Nramp1 is an integral membrane protein expressed exclusively in cells of the immune system and is recruited to the membrane of a phagosome upon phagocytosis. By controlling divalent cation concentrations Nramp1 may regulate the interphagosomal replication of bacteria. Mutations in Nramp1 may genetically predispose an individual to susceptibility to diseases including leprosy and tuberculosis conversely this might however provide protection form rheumatoid arthritis. Nramp2 is a multiple divalent cation transporter for Fe2+, Mn2+ and Zn2+ amongst others it is expressed at high levels in the intestine; and is major transferrin-independent iron uptake system in mammals. The yeast proteins Smf1 and Smf2 may also transport divalent cations.	1.71202e-62
NZ_CP009483.1|WP_023374001.1|6337992_6338856_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|367049	pfam02353, CMAS, Mycolic acid cyclopropane synthetase. This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.	1.33541e-166
NZ_CP009483.1|WP_023374019.1|6353345_6354182_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|235975	PRK07231, FabG-like, SDR family oxidoreductase.	4.37223e-74
NZ_CP009483.1|WP_023374028.1|6360069_6360339_-|DUF4242-domain-containing-protein	gnl|CDD|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	5.87399e-21
NZ_CP009483.1|WP_023373999.1|6336033_6337857_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.26757e-118
NZ_CP009483.1|WP_023373995.1|6333541_6335092_+|MFS-transporter	gnl|CDD|365860	pfam00083, Sugar_tr, Sugar (and other) transporter.	3.19722e-43
NZ_CP009483.1|WP_036394260.1|6365380_6365686_-|hypothetical-protein	gnl|CDD|227505	COG5178, PRP8, U5 snRNP spliceosome subunit [RNA processing and modification].	0.00573726
NZ_CP009483.1|WP_023374026.1|6357159_6360066_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	4.30032e-29
NZ_CP009483.1|WP_023374005.1|6340259_6341756_-|potassium/proton-antiporter	gnl|CDD|235410	PRK05326, PRK05326, potassium/proton antiporter.	0
NZ_CP009483.1|WP_036394264.1|6362067_6363510_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.17431e-107
NZ_CP009483.1|WP_023374030.1|6360707_6361739_+|esterase	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.964e-44
NZ_CP009483.1|WP_023374009.1|6342697_6345031_+|RNA-binding-transcriptional-accessory-protein	gnl|CDD|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NZ_CP009483.1|WP_023374007.1|6341909_6342614_+|TrkA-family-potassium-uptake-protein	gnl|CDD|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	1.22005e-43
NZ_CP009483.1|WP_036394270.1|6352789_6353272_-|flavin-reductase-family-protein	gnl|CDD|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	2.9614e-26

Protein sequences

>NZ_CP009483.1|WP_023374013.1|6345789_6347283_+|DUF4185-domain-containing-protein
MSAIHRVVSVSVASAAALGLISAVGLAPAATAVPCSGDAANAPPPPNAIVTNPGGTTLGPMTRGPRPRGANDRAPLPRLGPLSRLLNPAPRSAPLQQQAATPPHQAAVPPPAPPNPGNQPPNAAQLAPNAAPPPAPAPAAVPAPGAPDPGAALGGATTSLAEWVTGPDSPNKTLQQFGISGTDLGIIWDNGDPANHQVLMAFGDTFGYCAVNEHQWRYNTLFRSQDRDLGDGIHVAPGDAANRYSGSPVRQPGFSKQIISSIKWAPNETGIIPTSGVSVGKTQYVSFMSIRDWGRDGEWTTNYSGIAVSKDNGQNWGVYPGTIRASGPDSGRARFVPGNENFQMGAFVKSNDGYLYSFGTPPGRGGSAYLARVPQQFVPDLSKYQYWNGDSNSWVPGKPDAATPVIPGPVGEMSAQYNTYLKQYLVMYTNGMNDVVARTAPAPQGPWSPEQMLVSSWQMPGGIYAPMMHPWSTGKDVYFNLSLWSAYNVMLMHTTLG
>NZ_CP009483.1|WP_023374011.1|6344964_6345486_-|ATP-binding-protein
MLSHAFKFTFAGHVDVALRTLPKHVELTVHDTGIGEGRTAVSVPAVPPRPGSPATAPARAPASNWVRRRTGARPSEKLEATGRIRVASEVDTDTTFTVWIPLGRRRRDETVEGQPPRISEIAAALAEEAEQWDAQRDERAARGHTGPRRRPAHLPKPASRNARAIEPAGELAG
>NZ_CP009483.1|WP_023374009.1|6342697_6345031_+|RNA-binding-transcriptional-accessory-protein
MNPSTAIKSVTARLAEELAVEEAHVAAAVGLLDGGATVPFIARYRKEATGGLDDGQLRTLAERLQYLRELDERRAAVLASIREQGKLTDELRAALLSADTKSRVEDIYLPYKPKRRTKAQIAREAGLEPLADRLLSDPGLVPEAAAAAFVCADVGDAADVAAALEGARHIMVERAAEDAELVGAIREKFWAQGTLGSAPWSQDVAKSAAAQNFRDYFGFSESLQTMPSHRVLAVLRGEKEKILALTFDGGADDGYEAMVAASLGVDLSADVSAKAATPWLAATVRFAWRTRLMSSAAVDARIRLRQRAEQQAVAVFAKNLTHLLLAAPAGARTTLGLDPGFRTGVKVAVVDPTGKVVDTCAIYPHQPQRQWDLAKATLAALVARHSVELIAVGNGTASRETDTLAAELINDIRAAGGPALTKAMVSEAGASVYSASAYAARELPELDVTLRGAVSIARRLQDPLAELVKIDPKSIGVGQYQHDVTPAVLARSLDAVVEDAVNAVGVDLNTASIPLLSRVSGISESLAEAIVAYRDKTGAFASRRALLEVPRLGPKAFEQCAGFLRIRDGDDPLDASGVHPEAYPVVHRILDRTGLSLAEIIGDAGALRSLRPADFADDRFGIPTVIDILAELEKPGRDPRPTFTTATFAAGVQKIADLKVGMVLEGVVTNVAAFGAFVDIGVHQDGLVHVSAMAERFVADPHDVVRSGQVVRVKVIDVDVERRRIGLSLRLNDDPQRQPVSRPERRNSVHGKNFGRQPANSPAGSMARALRDAGFGR
>NZ_CP009483.1|WP_023374007.1|6341909_6342614_+|TrkA-family-potassium-uptake-protein
MRIAVAGAGKVGRSVAHELLDRGHKVLLIERQRNNFEPHTVPAADWLHADACELSTMHEAGVQTCDVLIAATGDDKANLVVGLLAKTEFGVPRVVARINDLHNEWLFGRSWGIDVAVSTPGAMIAGVEGAIDVGHLVRMMVLREGRAALTKLTLPEDNPLVGRRVCELDLPANTALVTVLRGDAVKVPQPGDVLRAGDEMLFIADSFLERSVWAAMYSTAPARASTRPGRPPSA
>NZ_CP009483.1|WP_023374005.1|6340259_6341756_-|potassium/proton-antiporter
MSLQQLYLALLIGGLVLLASIVGTRLATRVGFPSMLLFLLVGVAVGEDGLGLKFDDVQLARNVGTAALALILVEGGLTTRFTDIRTVLGPAATLATVGVLGSTAVTAVGAHLLLRVDWQVALLLGAIVSSTDAAAVFSVLRVLPLPRRVAGLLEAESGFNDAPAVILVLMFSAVPFAVEPGRAIADLLFELLAGAAVGVAIGYLGAFALRRIALPASGLYPIATFGLGLVAFAAAGASHASGFIAAYLAAVVLANTGLPHRSATRSFAEGVGWLAQIGLFVLLGLLVNPGEVAHDVVAAIVVGLLLLLIARPLSVVASLAAFRIPWHDQVFLSLAGLRGAVPIVLATFPVVAGVPDSYRLLNIVFMLVVVFTLVQGPSLRPIAHRLGLFSREATREIQVEAAPLDVLDAELLTMTVQPPSRLHNVTVLELRLPDPAVITLIIRNGHTFVPMPDTRIERGDELLIVTTSKTRAAAESRLRAVSRRGKLAYWFDEYGEPD
>NZ_CP009483.1|WP_023374003.1|6338952_6340293_+|acetyltransferase
MPATQFDAAATAHHTPADRDRAVDVARLGALVVVMFGHCALLLATIDSHGVRIANLLGELPALTPITWLVQVMPLFFLAGGAAGAYGWHAGAPWGTWLFTRAQRLCRPVFWYLACWVTALLAVRVTLGAESAVALGRECVALLWFLGVYLVVLAFVPVLTRLRTGRGVAAVVASLLAAATAVDQIRFAAGTPESGVANFLIVWLIPVVIGVGYARRLIGPRIALVAAGCAFTAQLKLALTSAYDVSLVVTGAERMSNVSPPTLLLALHCTWMSCAFVAAAGAIRRWAARPRVWHVVAVGNGGAMTLYLWHIPSIAVAAVALHAAGLDAYEVHAPGFWARLALRAIVFTIVMAGVFRLLAPLEHRRLPWWDGPVQATGVRSVAAGVLVVAAGVALVALAKNGLGGVEGWTALGCFLAALLAARTSSGPVSWPTPAGRQSGSPYSSNQ
>NZ_CP009483.1|WP_023374001.1|6337992_6338856_+|class-I-SAM-dependent-methyltransferase
MAGQLTPHFDDVQAHYDLSDDFFRLFLDPTQTYSCAYFERDDMTLEQAQLAKIDLSLGKLGLQPGMTLLDVGCGWGATMRRAIEKYGVNVVGLTLSKNQAAHVQKTFDELDSPRSRTVLLAGWEQFDEPVDRIVSIGAFEHFGHDRHADFFARAYQMLPADGAMLLHTITGLTMQQMVDAGLPLTLWLARFLKFIQTEIFPGGHPPTIEMVGEQSAKAGFTLTRRQSLRLHYARTLDLWAEALQAHQDEAIAIQSEEVYERYMKYLTGCAKLFRDGYIDVNQFTLQK
>NZ_CP009483.1|WP_023373999.1|6336033_6337857_+|serine/threonine-protein-kinase
MGDTTADSREGSQFGQYRLRRLVGRGAMGDVYEAEDTVRERVVALKLMSPTLSSDPVFRTRMQREARTAGRLHEPHVVPIHDYGEIDGQLYVDMRLIDGKDLAAILKRYGPLTPPRAVAVVRQIGSALDAAHAAGVTHRDVKPENILVSGDDFAYLVDFGIASATSDEKLTQLGSTVGTLYYMAPERFANTEVTYRADIYALACVLYECLTGSPPYRGDQLSVMGAHLSQAIPRPSAARPGIPAAFDQVIARGMAKDPADRYATCGDLSAAAYAALATPDQDRATDILQRSQVAQLPAAAVGQPAAGFAPPMPTPSTPAAQPAGWSPPTPPGSPVPTGAPQPTPWTGATGWGTGYPGTAGAPPWGQPPVQPSGGGGAPWLWVGVAVAVVVAVAAGLGIVVAKPWRSSAPRPGPTSPPAADAVELRVLNDGVFVGSSAAATTIDIFNEPICPPCGAFIRSYASDIETAVADKKLAVRYHLLNFLDDQSHTKNYSTRAVAASYCVADQNDPKVYSDFYAALFGSDFQPQEGAASDRTDAELAHLAQTVGANTTAISCIKSGSDRGTAQSKAAAASETLATFSANGTPFVWDGKKAVDLQNSSWLTRLTG
>NZ_CP009483.1|WP_042314102.1|6335160_6335901_+|hypothetical-protein
MTSTLLDEALEAHGGLQRWQSAAEIHSRVRSGGLLVRTRVPGNRFEDYRITVDVQEPRTVIDPFPVDGQRGVFDNGTVRIESHDGHVISSRANPRPAFFGRSGLRRNFRWDPLDSVYFAGYAMWNYLTTPYLLTRDGVEVDEAGTWREGGETWRRLNATFPAHIHTHSPRQSFYFDAGGRLRRHDYVAEVVGHWARAAHYCTEPVDAGGLVFQTRRRVYPIGPGNRPLPAPTLVSMQLSDLRVDTG
>NZ_CP009483.1|WP_023373995.1|6333541_6335092_+|MFS-transporter
MSASAQTGTITTQVPARLDRLPWGRFHWRVVIGLGGVWILDGLEVTMVGNVSSRLTEHGSGIELNAADIGLAASFYIAGACLGALFFGHLTDRFGRRNLFLLTLAVYLIATVATAFAFAPWYFFLTRFFTGSGIGGEYAAINSAIDELIPARVRGRVDLVINGTYWLGSAAGAAGALVVLDTSNFPPNIGWRLAFGVGAIFGIFVLLVRRNVPESPRWLFIHGREHEAERIVGEIEGEVERDTGQPLPEPQGRPLKVRQRHTISFWEIARVAFTLYPRRAVLGLALFIGQAFLYNGVTFNLGTLLSGFYGVASAHVPVFFIVWALSNFVGPLVLGRLFDTIGRKPMITFSYIGSAVVAVVLAALFVTGTGGVWTFIIVLAVAFFLASAGASAAYLTVSEIFPMETRALAIAFFYATGTAIGGISGPLLFGQLINSGQRSQVFWSFLIGAVVMAAAGLVELWLGVAAERRPLEELALPLTVADAEQDEEPTDARDRQRAGTAPVHDDDPHGGHAERP
>NZ_CP009483.1|WP_036394270.1|6352789_6353272_-|flavin-reductase-family-protein
MEAFDKLVSLLDYPIFVVTAAAGGAPAGCLVGFASQASIHPPRFLVGLSQQNHTFRVAAGADHLAVHLFDREHLDVVELFGSRSGDTVNKFDRCSWHLGPARTPILDDAAAWFVGRILDRFPLGDHVGYLLEPVDGSPPHQLEQWVSFRDVRGLPPGHEA
>NZ_CP009483.1|WP_023374019.1|6353345_6354182_-|NAD(P)-dependent-oxidoreductase
MNDPMHGRPLLADRVAVVTGGGGGIGAATSRLFAEHGARVVVADIDPDLAQQTVAEIGDPAFAVVTDVRDAGQVRALARTVLDRCGRADVLVNNVGHWLRHPGDFVDTHPELWDELYRVNLHHVLLATHAFLPAMIDRHAGAIVNVSSVEGLRGYPEDPVYAAFKAAVIHFTRSLAVQVGHHGVRVNAIAPDVTESLQVPYSQWLSDDEKAQWPQWVPVGRMGVPLDQARAILFLACDLSAFVTGHTIPTDGGTGAAGGWFRSSRRPDREWTNRPIAP
>NZ_CP009483.1|WP_036394268.1|6354332_6355610_+|divalent-metal-cation-transporter
MTGASRTSEERSSPRSVRSRGRWALLAVWGPGLVVMLADTDAGSLITAAQSGAQWGYRMVLPQLILMPILYVVQEMTVRLGIVTGRGHGALIRERFGRGWAWLSAFTLFASAIGALLTEFVGVAGVGELFGVSRWVSIPIATTMLLALALTGSYRRVERIGLAIGAAELAFLVAMVMARPQFDALLAGLSSMPLGNSSYLLLVAANVGAVIMPWMIFYQQGAVVDKHLSVATIRQARYDTATGAVLTQLIMIAVVLTVAATIGTHQEAAPLQTVGQIAGALTPYLGKLGGTVLFGLGMLGAALVAAIVASLAGAWGLSEVFGWQHTLNQRPTRATAKFYTTYALAHLVGAALVLGSVDLVNLAVDVEVMNALLLPIVLGLLLVLEARALPEQWRMSGVRKYTTRALCLVVIAFGLYMVPQALGWT
>NZ_CP009483.1|WP_023374024.1|6355627_6357004_-|FAD-binding-oxidoreductase
MSLTTETDELRTRLGAQLILPDDPGYDEARAVHNAMIDKRPAMIARCASAADVAAALEFARTSNLAVAIRGGGHNGPGFGTVDGGLVIDLSPMNRIDVDADRRTVRVQGGATWGQVDAATSAHGLATPSGIISTTGVGGLTLGGGHGYLSRKYGLTIDNLLEAELVLADGRMVTASESQHPDLFWALRGGGGNFGVATAFTFRLHPVPTVICGPTAWPASATADILSWYRDYLPAQDEDLYGFFAAMTVPPVAPFPEAFHLHKACAVVWCYTGDPAAAEEVFAPVRQMEPAFDGLGAAPYPALQTTFDALYPKGLQWYWRGDFFRTIPDGAVQAHARFTEELPTMHSTMHLYPIDGAVHRAGPTDTAWAYRDVNFSQVIAGVDPDPANAAALKRWTVDYWDATHPYSAGGAYVNFMMDEGQDRVRATYGPNYRRLSEVKATYDPHNVFHINQNIVPAR
>NZ_CP009483.1|WP_023374026.1|6357159_6360066_+|helix-turn-helix-transcriptional-regulator
MAQWVQPPLPAELIARRGGPMVGRDAELAVFEQAWERVESGNRQAVFVGGEPGAGKTRLVAEVAGTLAEHGVAVLVGGSTADAGVPYAPFTEALDRLLTTGPPGSMGELLADVAVQLRRLTTEVDRHLPGVAAEDDVGAPRRALFDALTGFLRRLSVDRPIALVLEDLHWAQLPTLAMLEHVLIGCADVRMLVVATFRTTEPDRTEELVTRLADLHRFDGVRRLDLEGLDTEAIAEFVRRTQQLPTPSLRSTAALLRDKTGGNPFFLNELCNHLEIRGGIAALGSQRTVPASIGDAIARRLGGLGATVREVVEQAAVLGQTFDLPALIATSQTDLTATLAAVDSAEAVGLVRAVPDSDGEFAFVHALTREAVLGGMAASRLRILHARAAEALQGRADPSVIPRLANHYLVAHVLGYHEQALRYAGQAARMAEQSLAYEDAAKWYERAASLAELKLADRAKLNLWAAANHMRAGDFARARAIYERISAIEDPLIRLEAAVGYEDASWRPGLADSKAADLLASALESCGLDTDDPRYIHALGSFGRALGFAGEAARAREISDRAIELARAVDDPTVVQHALMTSLWHLTPDMCAIQEERSTELLHAAQARRDYDALGSAAHFRAMVSYLTGRPEALAASAADMQRSVQACGQPFFGFISACVEQALAFLRGDFAGAERWADIALRTGNSFGADGTEGSHGVQMFMIRRETGGLDRFAGFVDGSERFAGRWVPGLLALYTELNCERGMARALNHLLNRNLGDHTDEAQWTMELVFMTEAALALGNREAVHALRPFIARYAGKNLLAGQFVALFGSADRYLARIAALGGDDQAAERLFGAALEMDRRMGSVVHVSETLARQALFEASRGRAEAARRLADEACAIAGPIGQVRVLGLVDSLLTGDLAGPDGLTDREIEVLRLLAAGLSNRAIGERLYISTNTAANHVRSILIKTGAANRTQAAMYAADHQLLG
>NZ_CP009483.1|WP_023374028.1|6360069_6360339_-|DUF4242-domain-containing-protein
MPIFMVERTYAEKLEPTFEVADGINRINAEEGVRWLYSFLSADKRKTYCLYEAPSPEAIRTAASRAGLPADVIVEVSERVLPDGASTDI
>NZ_CP009483.1|WP_023374030.1|6360707_6361739_+|esterase
MVMIKNPRHTRARKPDGRRIHHRHSPQSIAVSLASRLIVKNTVRAWAIQPNLRWPFDYIDSLAGLLPRFRSSVRIDPVRLDHCAAEWVRATGVSPTRAILYLHGGAFLTCGLNTHRSLVCRLSRAADAGVLTVGYRKLPSYQITDAIEDALSGLSWLQDHGFDGEQVVVAGDSAGGYLAFMTTLSAIRSHLAKPAGIATVSPFTDPDPARKLAHRNARRCSMFTCGALSMFARYLGEVQLPQDRPKSSRRVESPVDADLSPLPPVAIHASSDELLLADAELMAKRLTAAGIRCDLHLWDGQIHDFPLAADVLPEGRRAIRYLGDFVKEVTDGCAARTPAAAAG
>NZ_CP009483.1|WP_036394264.1|6362067_6363510_+|serine/threonine-protein-kinase
MPLAEGSTFAGYTIVRQLGSGGMGEVYLARHPRLPRQDALKVLRPEVSADTEYRERFNREADAAASLWHPHIVAVHDRGETDGQLWIDMDYVDGVDAVRLLRERYPNGMPGPEVTAIITAVAEALDYAHEHKLLHRDVKPANILIAKPDSPDRRIMLADFGIAGWVGEASGLTATNMTVGTVSYAAPEQLMGQDLDGRADQYALAATAFHLLTGTPPFQHSNPAVVISQHLSASPPPIGDRLPALADLDPVFAKALAKDPKDRYQRCIDFARALGHRLGGGGDADETIARPVAVPVPPAKRSLVRPAVLIPALLAILLVIATLVALREFQRADDERVVSATTSGSPATTTTSAPTTSTTTTSTTTPPTTPSTTAAAQTETTTSAAPAPVVVIGAVCAPQGSTGLTKTGATAYCSTLQGTNTTIWSLTPGTVASPTIPATAEPTESPLPTEQESPIRICMQQTGQTRRQCREEIRRSNGWP
>NZ_CP009483.1|WP_042313105.1|6363578_6364922_-|PPE-family-protein
MIAQIWMAWPPEAHSTTLSSGPGPGPLLAAADAWTSLSTEYADAAAELTVLLAGVQAADWQGPSAESYAAAHLPYVAWLTKASSDSLDAAAQHETVAAAYTSALAAMPTLGELAANHIAHAVLMATNFFGINAIPIALNEADYARMWVQAAVTMSVYAAVSGAALVAAPHPPPAPAIVKHHVGHVGSFPPPPKPPWWNIIWQLLETLAHVLTQALWELVSEVARFGVQMLFDLLQLVVAYVVLLAGYVLQMVKILNLLISDLLVLLLDQVQLVLIFLDITLRAAMAVVQQLAVFLGKVLGTLYWAVDNAAAAVAQAIRELLGGAAMAAEMVGVSPAVPQTGVATPLPMGGFATSPVALSAGIAPATGSAAHAAAAASSVAAQAGASGSSAGSEVLASESGAEISSIAGTAPDGAVLRPAGLTVLNSEFGGDVAVPMLPGTWDSSMAS
>NZ_CP009483.1|WP_036394260.1|6365380_6365686_-|hypothetical-protein
MRPWKRPAAVLATAVLAFTAVPEVFAIMAPSAQANADVCVNAGRRVSVSGCANIADAVAPYVPPPSEYAPLPEDYPPPPPPAPNINVCANVGRRISVSGCV

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP009483_11	11.1|3373828|26|NZ_CP009483|CRISPRCasFinder	3373828-3373853	26	NZ_CP009483.1	3373889-3373914	0	1.0
NZ_CP009483_17	17.1|4868308|48|NZ_CP009483|PILER-CR	4868308-4868355	48	NZ_CP009483.1	4866622-4866669	0	1.0
NZ_CP009483_17	17.1|4868308|48|NZ_CP009483|PILER-CR	4868308-4868355	48	NZ_CP009483.1	4866988-4867035	0	1.0
NZ_CP009483_17	17.1|4868308|48|NZ_CP009483|PILER-CR	4868308-4868355	48	NZ_CP009483.1	4867285-4867332	0	1.0
NZ_CP009483_17	17.1|4868308|48|NZ_CP009483|PILER-CR	4868308-4868355	48	NZ_CP009483.1	4867795-4867842	0	1.0
NZ_CP009483_17	17.1|4868308|48|NZ_CP009483|PILER-CR	4868308-4868355	48	NZ_CP009483.1	4868674-4868721	0	1.0
NZ_CP009483_17	17.3|4868452|48|NZ_CP009483|PILER-CR	4868452-4868499	48	NZ_CP009483.1	4866838-4866885	0	1.0
NZ_CP009483_17	17.3|4868452|48|NZ_CP009483|PILER-CR	4868452-4868499	48	NZ_CP009483.1	4867135-4867182	0	1.0
NZ_CP009483_17	17.3|4868452|48|NZ_CP009483|PILER-CR	4868452-4868499	48	NZ_CP009483.1	4867645-4867692	0	1.0
NZ_CP009483_17	17.3|4868452|48|NZ_CP009483|PILER-CR	4868452-4868499	48	NZ_CP009483.1	4868158-4868205	0	1.0
NZ_CP009483_17	17.4|4868524|54|NZ_CP009483|PILER-CR	4868524-4868577	54	NZ_CP009483.1	4866544-4866597	0	1.0
NZ_CP009483_17	17.4|4868524|54|NZ_CP009483|PILER-CR	4868524-4868577	54	NZ_CP009483.1	4867207-4867260	0	1.0
NZ_CP009483_17	17.4|4868524|54|NZ_CP009483|PILER-CR	4868524-4868577	54	NZ_CP009483.1	4868230-4868283	0	1.0
NZ_CP009483_17	17.5|4868602|48|NZ_CP009483|PILER-CR	4868602-4868649	48	NZ_CP009483.1	4866622-4866669	0	1.0
NZ_CP009483_17	17.5|4868602|48|NZ_CP009483|PILER-CR	4868602-4868649	48	NZ_CP009483.1	4866988-4867035	0	1.0
NZ_CP009483_17	17.5|4868602|48|NZ_CP009483|PILER-CR	4868602-4868649	48	NZ_CP009483.1	4867285-4867332	0	1.0
NZ_CP009483_17	17.5|4868602|48|NZ_CP009483|PILER-CR	4868602-4868649	48	NZ_CP009483.1	4867795-4867842	0	1.0
NZ_CP009483_17	17.5|4868602|48|NZ_CP009483|PILER-CR	4868602-4868649	48	NZ_CP009483.1	4868674-4868721	0	1.0
NZ_CP009483_18	18.1|4868891|42|NZ_CP009483|CRT	4868891-4868932	42	NZ_CP009483.1	4867502-4867543	0	1.0
NZ_CP009483_18	18.1|4868891|42|NZ_CP009483|CRT	4868891-4868932	42	NZ_CP009483.1	4868012-4868053	0	1.0
NZ_CP009483_18	18.1|4868891|42|NZ_CP009483|CRT	4868891-4868932	42	NZ_CP009483.1	4869401-4869442	0	1.0
NZ_CP009483_18	18.3|4869035|42|NZ_CP009483|CRT	4869035-4869076	42	NZ_CP009483.1	4866473-4866514	0	1.0
NZ_CP009483_18	18.4|4869107|48|NZ_CP009483|CRT	4869107-4869154	48	NZ_CP009483.1	4866545-4866592	0	1.0
NZ_CP009483_18	18.4|4869107|48|NZ_CP009483|CRT	4869107-4869154	48	NZ_CP009483.1	4867208-4867255	0	1.0
NZ_CP009483_18	18.4|4869107|48|NZ_CP009483|CRT	4869107-4869154	48	NZ_CP009483.1	4868231-4868278	0	1.0
NZ_CP009483_18	18.5|4869185|42|NZ_CP009483|CRT	4869185-4869226	42	NZ_CP009483.1	4866623-4866664	0	1.0
NZ_CP009483_18	18.5|4869185|42|NZ_CP009483|CRT	4869185-4869226	42	NZ_CP009483.1	4866989-4867030	0	1.0
NZ_CP009483_18	18.5|4869185|42|NZ_CP009483|CRT	4869185-4869226	42	NZ_CP009483.1	4867286-4867327	0	1.0
NZ_CP009483_18	18.5|4869185|42|NZ_CP009483|CRT	4869185-4869226	42	NZ_CP009483.1	4867796-4867837	0	1.0
NZ_CP009483_18	18.5|4869185|42|NZ_CP009483|CRT	4869185-4869226	42	NZ_CP009483.1	4868675-4868716	0	1.0
NZ_CP009483_18	18.6|4869257|42|NZ_CP009483|CRT	4869257-4869298	42	NZ_CP009483.1	4866695-4866736	0	1.0
NZ_CP009483_18	18.6|4869257|42|NZ_CP009483|CRT	4869257-4869298	42	NZ_CP009483.1	4867358-4867399	0	1.0
NZ_CP009483_18	18.6|4869257|42|NZ_CP009483|CRT	4869257-4869298	42	NZ_CP009483.1	4868747-4868788	0	1.0
NZ_CP009483_7	7.6|1937647|17|NZ_CP009483|CRISPRCasFinder	1937647-1937663	17	NZ_CP009483.1	5777165-5777181	1	0.941
NZ_CP009483_17	17.3|4868452|48|NZ_CP009483|PILER-CR	4868452-4868499	48	NZ_CP009483.1	4866472-4866519	1	0.979
NZ_CP009483_18	18.3|4869035|42|NZ_CP009483|CRT	4869035-4869076	42	NZ_CP009483.1	4866839-4866880	1	0.976
NZ_CP009483_18	18.3|4869035|42|NZ_CP009483|CRT	4869035-4869076	42	NZ_CP009483.1	4867136-4867177	1	0.976
NZ_CP009483_18	18.3|4869035|42|NZ_CP009483|CRT	4869035-4869076	42	NZ_CP009483.1	4867646-4867687	1	0.976
NZ_CP009483_18	18.3|4869035|42|NZ_CP009483|CRT	4869035-4869076	42	NZ_CP009483.1	4868159-4868200	1	0.976
NZ_CP009483_4	4.2|1061833|22|NZ_CP009483|CRISPRCasFinder	1061833-1061854	22	NZ_CP009483.1	3816744-3816765	2	0.909
NZ_CP009483_5	5.6|1062274|22|NZ_CP009483|CRISPRCasFinder	1062274-1062295	22	NZ_CP009483.1	2939459-2939480	2	0.909
NZ_CP009483_9	9.1|2785051|20|NZ_CP009483|CRISPRCasFinder	2785051-2785070	20	NZ_CP009483.1	6117051-6117070	2	0.9
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NZ_CP009483.1	2717721-2717741	2	0.905
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NZ_CP009483.1	5755828-5755848	2	0.905
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP009483.1	3557648-3557668	2	0.905
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP009483.1	4324327-4324347	2	0.905
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	NZ_CP009483.1	3113960-3113980	2	0.905
NZ_CP009483_17	17.4|4868524|54|NZ_CP009483|PILER-CR	4868524-4868577	54	NZ_CP009483.1	4867717-4867770	2	0.963
NZ_CP009483_18	18.2|4868963|42|NZ_CP009483|CRT	4868963-4869004	42	NZ_CP009483.1	4867574-4867615	2	0.952
NZ_CP009483_18	18.4|4869107|48|NZ_CP009483|CRT	4869107-4869154	48	NZ_CP009483.1	4867718-4867765	2	0.958

1. spacer 11.1|3373828|26|NZ_CP009483|CRISPRCasFinder matches to position: 3373889-3373914, mismatch: 0, identity: 1.0

ttgccgtatcgagcgtgcggtggtgc	CRISPR spacer
ttgccgtatcgagcgtgcggtggtgc	Protospacer
**************************

2. spacer 17.1|4868308|48|NZ_CP009483|PILER-CR matches to position: 4866622-4866669, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

3. spacer 17.1|4868308|48|NZ_CP009483|PILER-CR matches to position: 4866988-4867035, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

4. spacer 17.1|4868308|48|NZ_CP009483|PILER-CR matches to position: 4867285-4867332, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

5. spacer 17.1|4868308|48|NZ_CP009483|PILER-CR matches to position: 4867795-4867842, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

6. spacer 17.1|4868308|48|NZ_CP009483|PILER-CR matches to position: 4868674-4868721, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

7. spacer 17.3|4868452|48|NZ_CP009483|PILER-CR matches to position: 4866838-4866885, mismatch: 0, identity: 1.0

cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	CRISPR spacer
cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	Protospacer
************************************************

8. spacer 17.3|4868452|48|NZ_CP009483|PILER-CR matches to position: 4867135-4867182, mismatch: 0, identity: 1.0

cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	CRISPR spacer
cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	Protospacer
************************************************

9. spacer 17.3|4868452|48|NZ_CP009483|PILER-CR matches to position: 4867645-4867692, mismatch: 0, identity: 1.0

cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	CRISPR spacer
cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	Protospacer
************************************************

10. spacer 17.3|4868452|48|NZ_CP009483|PILER-CR matches to position: 4868158-4868205, mismatch: 0, identity: 1.0

cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	CRISPR spacer
cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	Protospacer
************************************************

11. spacer 17.4|4868524|54|NZ_CP009483|PILER-CR matches to position: 4866544-4866597, mismatch: 0, identity: 1.0

gacaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatgttggt	CRISPR spacer
gacaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatgttggt	Protospacer
******************************************************

12. spacer 17.4|4868524|54|NZ_CP009483|PILER-CR matches to position: 4867207-4867260, mismatch: 0, identity: 1.0

gacaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatgttggt	CRISPR spacer
gacaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatgttggt	Protospacer
******************************************************

13. spacer 17.4|4868524|54|NZ_CP009483|PILER-CR matches to position: 4868230-4868283, mismatch: 0, identity: 1.0

gacaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatgttggt	CRISPR spacer
gacaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatgttggt	Protospacer
******************************************************

14. spacer 17.5|4868602|48|NZ_CP009483|PILER-CR matches to position: 4866622-4866669, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

15. spacer 17.5|4868602|48|NZ_CP009483|PILER-CR matches to position: 4866988-4867035, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

16. spacer 17.5|4868602|48|NZ_CP009483|PILER-CR matches to position: 4867285-4867332, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

17. spacer 17.5|4868602|48|NZ_CP009483|PILER-CR matches to position: 4867795-4867842, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

18. spacer 17.5|4868602|48|NZ_CP009483|PILER-CR matches to position: 4868674-4868721, mismatch: 0, identity: 1.0

gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	CRISPR spacer
gccaatagtggggtggcggctagtgcggatggtcgtatcaatgtggcc	Protospacer
************************************************

19. spacer 18.1|4868891|42|NZ_CP009483|CRT matches to position: 4867502-4867543, mismatch: 0, identity: 1.0

ccaacaatggggtggcggccggtgcggatggcagcctcaaca	CRISPR spacer
ccaacaatggggtggcggccggtgcggatggcagcctcaaca	Protospacer
******************************************

20. spacer 18.1|4868891|42|NZ_CP009483|CRT matches to position: 4868012-4868053, mismatch: 0, identity: 1.0

ccaacaatggggtggcggccggtgcggatggcagcctcaaca	CRISPR spacer
ccaacaatggggtggcggccggtgcggatggcagcctcaaca	Protospacer
******************************************

21. spacer 18.1|4868891|42|NZ_CP009483|CRT matches to position: 4869401-4869442, mismatch: 0, identity: 1.0

ccaacaatggggtggcggccggtgcggatggcagcctcaaca	CRISPR spacer
ccaacaatggggtggcggccggtgcggatggcagcctcaaca	Protospacer
******************************************

22. spacer 18.3|4869035|42|NZ_CP009483|CRT matches to position: 4866473-4866514, mismatch: 0, identity: 1.0

gtaatgctggggtgttggccagttcgcagggggtgcgcaata	CRISPR spacer
gtaatgctggggtgttggccagttcgcagggggtgcgcaata	Protospacer
******************************************

23. spacer 18.4|4869107|48|NZ_CP009483|CRT matches to position: 4866545-4866592, mismatch: 0, identity: 1.0

acaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatg	CRISPR spacer
acaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatg	Protospacer
************************************************

24. spacer 18.4|4869107|48|NZ_CP009483|CRT matches to position: 4867208-4867255, mismatch: 0, identity: 1.0

acaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatg	CRISPR spacer
acaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatg	Protospacer
************************************************

25. spacer 18.4|4869107|48|NZ_CP009483|CRT matches to position: 4868231-4868278, mismatch: 0, identity: 1.0

acaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatg	CRISPR spacer
acaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatg	Protospacer
************************************************

26. spacer 18.5|4869185|42|NZ_CP009483|CRT matches to position: 4866623-4866664, mismatch: 0, identity: 1.0

ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	CRISPR spacer
ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	Protospacer
******************************************

27. spacer 18.5|4869185|42|NZ_CP009483|CRT matches to position: 4866989-4867030, mismatch: 0, identity: 1.0

ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	CRISPR spacer
ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	Protospacer
******************************************

28. spacer 18.5|4869185|42|NZ_CP009483|CRT matches to position: 4867286-4867327, mismatch: 0, identity: 1.0

ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	CRISPR spacer
ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	Protospacer
******************************************

29. spacer 18.5|4869185|42|NZ_CP009483|CRT matches to position: 4867796-4867837, mismatch: 0, identity: 1.0

ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	CRISPR spacer
ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	Protospacer
******************************************

30. spacer 18.5|4869185|42|NZ_CP009483|CRT matches to position: 4868675-4868716, mismatch: 0, identity: 1.0

ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	CRISPR spacer
ccaatagtggggtggcggctagtgcggatggtcgtatcaatg	Protospacer
******************************************

31. spacer 18.6|4869257|42|NZ_CP009483|CRT matches to position: 4866695-4866736, mismatch: 0, identity: 1.0

gcaatagtggagttacggcggatgcggatggcagtgtcaatg	CRISPR spacer
gcaatagtggagttacggcggatgcggatggcagtgtcaatg	Protospacer
******************************************

32. spacer 18.6|4869257|42|NZ_CP009483|CRT matches to position: 4867358-4867399, mismatch: 0, identity: 1.0

gcaatagtggagttacggcggatgcggatggcagtgtcaatg	CRISPR spacer
gcaatagtggagttacggcggatgcggatggcagtgtcaatg	Protospacer
******************************************

33. spacer 18.6|4869257|42|NZ_CP009483|CRT matches to position: 4868747-4868788, mismatch: 0, identity: 1.0

gcaatagtggagttacggcggatgcggatggcagtgtcaatg	CRISPR spacer
gcaatagtggagttacggcggatgcggatggcagtgtcaatg	Protospacer
******************************************

34. spacer 7.6|1937647|17|NZ_CP009483|CRISPRCasFinder matches to position: 5777165-5777181, mismatch: 1, identity: 0.941

gcgggctgccggcgctg	CRISPR spacer
gcggggtgccggcgctg	Protospacer
***** ***********

35. spacer 17.3|4868452|48|NZ_CP009483|PILER-CR matches to position: 4866472-4866519, mismatch: 1, identity: 0.979

cgtaatgctggggtgttggccagtgcgcagggggtgcgcaatattgcg	CRISPR spacer
cgtaatgctggggtgttggccagttcgcagggggtgcgcaatattgcg	Protospacer
************************ ***********************

36. spacer 18.3|4869035|42|NZ_CP009483|CRT matches to position: 4866839-4866880, mismatch: 1, identity: 0.976

gtaatgctggggtgttggccagttcgcagggggtgcgcaata	CRISPR spacer
gtaatgctggggtgttggccagtgcgcagggggtgcgcaata	Protospacer
*********************** ******************

37. spacer 18.3|4869035|42|NZ_CP009483|CRT matches to position: 4867136-4867177, mismatch: 1, identity: 0.976

gtaatgctggggtgttggccagttcgcagggggtgcgcaata	CRISPR spacer
gtaatgctggggtgttggccagtgcgcagggggtgcgcaata	Protospacer
*********************** ******************

38. spacer 18.3|4869035|42|NZ_CP009483|CRT matches to position: 4867646-4867687, mismatch: 1, identity: 0.976

gtaatgctggggtgttggccagttcgcagggggtgcgcaata	CRISPR spacer
gtaatgctggggtgttggccagtgcgcagggggtgcgcaata	Protospacer
*********************** ******************

39. spacer 18.3|4869035|42|NZ_CP009483|CRT matches to position: 4868159-4868200, mismatch: 1, identity: 0.976

gtaatgctggggtgttggccagttcgcagggggtgcgcaata	CRISPR spacer
gtaatgctggggtgttggccagtgcgcagggggtgcgcaata	Protospacer
*********************** ******************

40. spacer 4.2|1061833|22|NZ_CP009483|CRISPRCasFinder matches to position: 3816744-3816765, mismatch: 2, identity: 0.909

gacggtacccgagttgaagaag	CRISPR spacer
gacgacacccgagttgaagaag	Protospacer
****..****************

41. spacer 5.6|1062274|22|NZ_CP009483|CRISPRCasFinder matches to position: 2939459-2939480, mismatch: 2, identity: 0.909

gccgctgcccaagttgaacgag	CRISPR spacer
gccgctgcccatgttgagcgag	Protospacer
*********** *****.****

42. spacer 9.1|2785051|20|NZ_CP009483|CRISPRCasFinder matches to position: 6117051-6117070, mismatch: 2, identity: 0.9

ggcgggcggggatggcgggc	CRISPR spacer
ggcgggcggggctgccgggc	Protospacer
*********** ** *****

43. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to position: 2717721-2717741, mismatch: 2, identity: 0.905

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgccggtgccgccggt	Protospacer
**********..*********

44. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to position: 5755828-5755848, mismatch: 2, identity: 0.905

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgccggccccgccggt	Protospacer
**********.* ********

45. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to position: 3557648-3557668, mismatch: 2, identity: 0.905

accgccgccgacgccgcccac	CRISPR spacer
accgccgacgacgccacccac	Protospacer
******* *******.*****

46. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to position: 4324327-4324347, mismatch: 2, identity: 0.905

accgccgccgacgccgcccac	CRISPR spacer
accgcggccgccgccgcccac	Protospacer
***** **** **********

47. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to position: 3113960-3113980, mismatch: 2, identity: 0.905

ggggccgctgtcgccgccggt	CRISPR spacer
ggtgccgatgtcgccgccggt	Protospacer
** **** *************

48. spacer 17.4|4868524|54|NZ_CP009483|PILER-CR matches to position: 4867717-4867770, mismatch: 2, identity: 0.963

gacaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatgttggt	CRISPR spacer
gacaatgtgattgatgtggccagtgcgatcgcggtgggggagaccaatgttggt	Protospacer
****************.*** *********************************

49. spacer 18.2|4868963|42|NZ_CP009483|CRT matches to position: 4867574-4867615, mismatch: 2, identity: 0.952

acaatggtggggttgtggcgggggcgagcggtgacacgaaca	CRISPR spacer
acaatggtggggttgtggcgggggcgagcggggacgcgaaca	Protospacer
******************************* ***.******

50. spacer 18.4|4869107|48|NZ_CP009483|CRT matches to position: 4867718-4867765, mismatch: 2, identity: 0.958

acaatgtgattgatgcggcgagtgcgatcgcggtgggggagaccaatg	CRISPR spacer
acaatgtgattgatgtggccagtgcgatcgcggtgggggagaccaatg	Protospacer
***************.*** ****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP040723	Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence	81988-82008	0	1.0
NZ_CP009483_1	1.2|466019|21|NZ_CP009483|CRISPRCasFinder	466019-466039	21	NZ_AP018921	Pseudonocardia autotrophica strain NBRC 12743 plasmid pPA12743CP, complete sequence	160370-160390	1	0.952
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NC_019407	Caulobacter phage CcrMagneto, complete genome	37128-37150	1	0.957
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	429389-429409	1	0.952
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NZ_LR134447	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 5, complete sequence	187257-187277	1	0.952
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NC_008758	Polaromonas naphthalenivorans CJ2 plasmid pPNAP02, complete sequence	144171-144191	1	0.952
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	104232-104252	1	0.952
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	324770-324790	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2191434-2191454	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	82917-82937	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP016820	Rhodococcus sp. p52 plasmid pDF02, complete sequence	24644-24664	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	MN908693	Gordonia phage AnClar, complete genome	56524-56544	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	MK801725	Gordonia phage Yago84, complete genome	54815-54835	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1730210-1730230	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP020811	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed2, complete sequence	49511-49531	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP020811	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed2, complete sequence	135843-135863	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP023713	Rhodococcus ruber strain YC-YT1 plasmid unnamed2, complete sequence	31949-31969	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP053567	Pseudonocardia sp. Gen01 plasmid unnamed3, complete sequence	18044-18064	1	0.952
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	MH105773	Vibrio phage Rostov-6, complete genome	11348-11368	1	0.952
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	NZ_CP035092	Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence	112735-112755	1	0.952
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	NC_008688	Paracoccus denitrificans PD1222 plasmid 1, complete sequence	360082-360102	1	0.952
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	249847-249867	1	0.952
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	411237-411257	1	0.952
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	AF068845	Mycobacteriophage TM4, complete genome	36951-36971	1	0.952
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	KC787101	Mycobacterium phage 33D, partial genome	11443-11463	1	0.952
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	NC_003387	Mycobacterium phage TM4, complete genome	36951-36971	1	0.952
NZ_CP009483_12	12.20|3551678|21|NZ_CP009483|CRISPRCasFinder	3551678-3551698	21	NZ_CP024936	Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence	91781-91801	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	506512-506532	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5852042-5852062	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1862724-1862744	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2436384-2436404	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	396621-396641	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	402855-402875	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	CP021185	Sphingomonas wittichii DC-6 plasmid pDC04, complete sequence	22830-22850	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	392812-392832	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	48516-48536	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	402855-402875	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	402867-402887	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	402888-402908	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	402854-402874	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP018224	Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL3, complete sequence	18268-18288	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP013267	Sphingobium baderi strain DE-13 plasmid pDE3, complete sequence	48171-48191	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	396651-396671	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP041019	Sphingobium fuliginis ATCC 27551 plasmid pSF2, complete sequence	46381-46401	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	245922-245942	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	396651-396671	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	396644-396664	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KP027207	Mycobacterium phage Chandler, complete genome	32148-32168	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MN096360	Mycobacterium phage Rita1961, complete genome	31352-31372	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MG839014	Mycobacterium phage RagingRooster, complete genome	31369-31389	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KJ194581	Mycobacterium phage Audrey, complete genome	31365-31385	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KR080203	Mycobacterium phage OrangeOswald, complete genome	31368-31388	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MH513976	Mycobacterium phage Morty007, complete genome	32147-32167	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MH051265	Mycobacterium phage Yahalom, complete genome	31378-31398	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MH316565	Mycobacterium phage Mortcellus, complete genome	32003-32023	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MT310871	Mycobacterium phage Jackstina, complete genome	31288-31308	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MK359357	Mycobacterium phage RomaT, complete genome	32142-32162	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	JF704095	Mycobacterium phage Daisy, complete sequence	31392-31412	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	EU816589	Mycobacterium phage Phaedrus, complete genome	31284-31304	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MN096359	Mycobacterium phage Obutu, complete genome	31351-31371	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MK061414	Mycobacterium phage Marley1013, complete genome	32147-32167	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MT952851	Mycobacterium phage Gervas, complete genome	31346-31366	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MG925353	Mycobacterium phage Nozo, complete genome	32127-32147	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_019410	Caulobacter phage CcrKarma, complete genome	40011-40031	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KJ194584	Mycobacterium phage Heathcliff, complete genome	31330-31350	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MN444872	Mycobacterium phage SynergyX, complete genome	31369-31389	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MH576977	Mycobacterium phage Tydolla, complete genome	32103-32123	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MG925338	Mycobacterium phage ChaChing, complete genome	31380-31400	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_023742	Mycobacterium phage Akoma, complete genome	31369-31389	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MG920059	Mycobacterium phage Baloo, complete genome	31368-31388	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_019407	Caulobacter phage CcrMagneto, complete genome	39202-39222	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_023686	Mycobacterium phage Gadjet, complete genome	31375-31395	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KR080205	Mycobacterium phage Corofin, complete genome	31390-31410	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_041965	Mycobacterium phage Athena, complete genome	32116-32136	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MT310892	Mycobacterium phage Compostia, complete genome	31795-31815	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	JN699018	Mycobacterium phage Kamiyu, complete genome	31334-31354	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_012027	Mycobacterium phage Phlyer, complete genome	32103-32123	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MN444873	Mycobacterium phage Abinghost, complete genome	31365-31385	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_019411	Caulobacter phage CcrSwift, complete genome	39164-39184	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP013298	Arthrobacter sp. YC-RL1 plasmid unnamed 1, complete sequence	59009-59029	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP010955	Sphingobium sp. YBL2 plasmid 1pYBL2-1, complete sequence	4187-4207	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_017081	Phycisphaera mikurensis NBRC 102666 plasmid pPSMK1, complete sequence	63642-63662	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	585129-585149	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	482283-482303	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP054615	Azospirillum oryzae strain KACC 14407 plasmid unnamed1, complete sequence	269137-269157	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_014007	Sphingobium japonicum UT26S plasmid pCHQ1, complete sequence	18528-18548	1	0.952
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP047221	Sphingobium yanoikuyae strain YC-JY1 plasmid unnamed2, complete sequence	24542-24562	1	0.952
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP054025	Rhizobium sp. JKLM12A2 plasmid pPR12A204, complete sequence	197386-197406	1	0.952
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP054034	Rhizobium sp. JKLM13E plasmid pPR13E03, complete sequence	160826-160846	1	0.952
NZ_CP009483_5	5.1|1062004|22|NZ_CP009483|CRISPRCasFinder	1062004-1062025	22	NC_015595	Sphingobium chlorophenolicum L-1 plasmid pSPHCH01, complete sequence	87401-87422	2	0.909
NZ_CP009483_5	5.6|1062274|22|NZ_CP009483|CRISPRCasFinder	1062274-1062295	22	NC_022044	Paracoccus aminophilus JCM 7686 plasmid pAMI6, complete sequence	191530-191551	2	0.909
NZ_CP009483_6	6.2|1524866|23|NZ_CP009483|CRISPRCasFinder	1524866-1524888	23	NZ_CP031358	Erythrobacter aureus strain YH-07 plasmid unnamed, complete sequence	66249-66271	2	0.913
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NC_019410	Caulobacter phage CcrKarma, complete genome	37940-37962	2	0.913
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NC_019411	Caulobacter phage CcrSwift, complete genome	37093-37115	2	0.913
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_LR134459	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence	39832-39854	2	0.913
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	MH617140	Microviridae sp. isolate ctce707, complete genome	4378-4400	2	0.913
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	CP047389	Agrobacterium sp. CGMCC 11546 plasmid pA	134005-134027	2	0.913
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	CP047389	Agrobacterium sp. CGMCC 11546 plasmid pA	239275-239297	2	0.913
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_CP023738	Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence	149720-149742	2	0.913
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP051182	Thalassobius gelatinovorus strain NEB572 plasmid pAge77, complete sequence	61404-61430	2	0.926
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	56865-56885	2	0.905
NZ_CP009483_12	12.15|3551444|21|NZ_CP009483|CRISPRCasFinder	3551444-3551464	21	NZ_CP040765	Paracoccus sp. 2251 plasmid unnamed1, complete sequence	64889-64909	2	0.905
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	946350-946370	2	0.905
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NC_005307	Gordonia westfalica strain DSM44215T plasmid pKB1 complete genome	96003-96023	2	0.905
NZ_CP009483_12	12.18|3551588|21|NZ_CP009483|CRISPRCasFinder	3551588-3551608	21	NZ_AP014811	Methylorubrum populi strain P-1M plasmid pMPPM02, complete sequence	16108-16128	2	0.905
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	210376-210396	2	0.905
NZ_CP009483_12	12.19|3551633|21|NZ_CP009483|CRISPRCasFinder	3551633-3551653	21	MF324914	Mycobacterium phage Krueger, complete genome	7288-7308	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	AM261282	Uncultured bacterium IncP-1 plasmid pKJK5 complete sequence	13878-13898	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP045074	Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence	193741-193761	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP026382	Sphingopyxis sp. MG plasmid pCMS1, complete sequence	20343-20363	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP015279	Mycobacterium chimaera strain DSM 44623 plasmid unnamed 1, complete sequence	31992-32012	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP006570	Sodalis praecaptivus strain HS1 plasmid pHS1, complete sequence	285426-285446	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP028340	Thauera aromatica K172 plasmid pKJK172, complete sequence	13099-13119	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	296562-296582	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	324773-324793	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP007256	Rhodococcus erythropolis R138 plasmid pCRE138, complete sequence	25043-25063	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KC964605	Uncultured bacterium plasmid pMLUA1, complete sequence	13877-13897	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KC964606	Uncultured bacterium plasmid pMLUA3, complete sequence	13877-13897	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KC964607	Uncultured bacterium plasmid pMLUA4, complete sequence	13877-13897	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_MN366356	Bacterium plasmid pALTS27, complete sequence	12563-12583	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_MN366360	Bacterium plasmid pALTS32, complete sequence	12563-12583	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	291334-291354	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	AP014018	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C106A-MedDCM-OCT-S35-C77, *** SEQUENCING IN PROGRESS ***	19880-19900	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_028802	Mycobacterium phage UnionJack, complete genome	22749-22769	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MK524490	Mycobacterium phage Donny, complete genome	31923-31943	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MF919502	Mycobacterium phage Demsculpinboyz, complete genome	21897-21917	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KJ567044	Mycobacterium phage EmpTee, complete genome	61405-61425	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	AY129336	Mycobacteriophage Che9d, complete genome	21912-21932	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_028828	Mycobacterium phage TheloniousMonk, complete genome	29950-29970	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MH669014	Mycobacterium phage Spikelee, complete genome	24971-24991	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KR080198	Mycobacterium phage Cambiare, complete genome	25013-25033	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	AY848685	Enterobacteria phage PR3, complete genome	11288-11308	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MT889380	Mycobacterium phage Coco12, complete genome	22540-22560	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KR080206	Mycobacterium phage ShedlockHolmes, complete genome	24461-24481	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_023698	Mycobacterium phage Avani, complete genome	21904-21924	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	JN699007	Mycobacterium phage Acadian, complete genome	31918-31938	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	AY848684	Enterobacteria phage L17, complete genome	11287-11307	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MG812486	Mycobacterium phage Acme, complete genome	28558-28578	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_028791	Mycobacterium phage MOOREtheMARYer, complete genome	23160-23180	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_028791	Mycobacterium phage MOOREtheMARYer, complete genome	24455-24475	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MN693628	Marine virus AFVG_250M875, complete genome	19358-19378	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MG925349	Mycobacterium phage Mendokysei, complete genome	22301-22321	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MT889381	Mycobacterium phage Suigeneris, complete genome	31923-31943	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KJ194580	Mycobacterium phage Badfish, complete genome	61856-61876	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_042323	Mycobacterium virus Mozy, complete genome	24395-24415	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MT114167	Mycobacterium phage Phanphagia, complete genome	22195-22215	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	KM347889	Mycobacterium phage BuzzLyseyear, complete genome	25524-25544	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	JF712866	Vibrio phage phiVC8, complete genome	10448-10468	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MK061411	Mycobacterium phage Faze9, complete genome	40784-40804	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	541825-541845	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP015268	Mycobacterium chimaera strain ZUERICH-2 plasmid unnamed 1, complete sequence	48970-48990	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	104229-104249	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	476040-476060	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	94689-94709	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	59768-59788	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	JQ004406	Uncultured bacterium plasmid pHH128, complete sequence	4916-4936	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	JQ004407	Uncultured bacterium plasmid pHH3408, complete sequence	4918-4938	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	JQ004408	Uncultured bacterium plasmid pHH3414, complete sequence	4918-4938	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	JQ004409	Uncultured bacterium plasmid pKS77, complete sequence	4789-4809	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NZ_CP014311	Burkholderia sp. PAMC 26561 plasmid unnamed4, complete sequence	182688-182708	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	740403-740423	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	AP014019	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C106A-MedDCM-OCT-S39-C83, *** SEQUENCING IN PROGRESS ***	12158-12178	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MN694400	Marine virus AFVG_250M1011, complete genome	20549-20569	2	0.905
NZ_CP009483_12	12.21|3551723|21|NZ_CP009483|CRISPRCasFinder	3551723-3551743	21	MN994497	Phage NBEco003, complete genome	9280-9300	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	1085951-1085971	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	1054777-1054797	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	1152173-1152193	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	656687-656707	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	773571-773591	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	293028-293048	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	373943-373963	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1226530-1226550	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	999213-999233	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	1085956-1085976	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	MN103533	Mycobacterium phage Weirdo19, complete genome	22947-22967	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	JX100810	Caulobacter phage CcrColossus, complete genome	50739-50759	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	MH588547	Caulobacter phage CcrSC, complete genome	68578-68598	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	651049-651069	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	650816-650836	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	635894-635914	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	232857-232877	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	643875-643895	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	633684-633704	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1301612-1301632	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	895108-895128	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	557861-557881	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1422475-1422495	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	794416-794436	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	657489-657509	2	0.905
NZ_CP009483_12	12.24|3551861|21|NZ_CP009483|CRISPRCasFinder	3551861-3551881	21	NZ_CP004394	Celeribacter indicus strain P73 plasmid pP73A, complete sequence	97457-97477	2	0.905
NZ_CP009483_3	3.1|1061638|22|NZ_CP009483|CRISPRCasFinder	1061638-1061659	22	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	386300-386321	3	0.864
NZ_CP009483_4	4.1|1061788|22|NZ_CP009483|CRISPRCasFinder	1061788-1061809	22	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	105479-105500	3	0.864
NZ_CP009483_6	6.1|1524818|23|NZ_CP009483|CRISPRCasFinder	1524818-1524840	23	NZ_CP033971	Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence	266829-266851	3	0.87
NZ_CP009483_6	6.1|1524818|23|NZ_CP009483|CRISPRCasFinder	1524818-1524840	23	NC_011758	Methylorubrum extorquens CM4 plasmid pCMU01, complete sequence	306629-306651	3	0.87
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_KM017071	Sphingomonas sp. JE1 plasmid pJE1, complete sequence	195333-195355	3	0.87
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	93604-93626	3	0.87
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_CP023524	Burkholderia gladioli pv. gladioli strain FDAARGOS_389 plasmid unnamed, complete sequence	113117-113139	3	0.87
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	CP000663	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence	20057-20079	3	0.87
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_CP053345	Herbiconiux sp. SALV-R1 plasmid unnamed1, complete sequence	33718-33740	3	0.87
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	MH588544	Caulobacter phage CcrBL10, complete genome	38137-38159	3	0.87
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NC_048047	Caulobacter phage CcrBL9, complete genome	68439-68461	3	0.87
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NC_048047	Caulobacter phage CcrBL9, complete genome	70176-70198	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443392	Rhodococcus hoagii strain PAM1340 plasmid pVAPA1340, complete sequence	44354-44376	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443389	Rhodococcus hoagii strain PAM1357 plasmid pVAPA1357, complete sequence	65280-65302	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443403	Rhodococcus hoagii strain PAM2288 plasmid pVAPA2288, complete sequence	65267-65289	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443388	Rhodococcus hoagii strain PAM1216 plasmid pVAPA1216, complete sequence	38473-38495	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443393	Rhodococcus hoagii strain PAM1637 plasmid pVAPA1637, complete sequence	65287-65309	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443402	Rhodococcus hoagii strain PAM2285 plasmid pVAPA2285, complete sequence	44329-44351	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443390	Rhodococcus hoagii strain PAM1422 plasmid pVAPA1422, complete sequence	37845-37867	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443395	Rhodococcus hoagii strain PAM2282 plasmid pVAPA2282, complete sequence	65270-65292	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443404	Rhodococcus hoagii strain PAM2287 plasmid pVAPA2287, complete sequence	63387-63409	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443405	Rhodococcus hoagii strain PAM2279 plasmid pVAPA2279, complete sequence	65285-65307	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443391	Rhodococcus hoagii strain PAM1600 plasmid pVAPA1600, complete sequence	37845-37867	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443394	Rhodococcus hoagii strain PAM1643 plasmid pVAPA1643, complete sequence	44329-44351	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443396	Rhodococcus hoagii strain PAM1271 plasmid pVAPA1271, complete sequence	37847-37869	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443406	Rhodococcus hoagii strain PAM1413 plasmid pVAPB1413, complete sequence	38140-38162	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443397	Rhodococcus hoagii strain PAM1475 plasmid pVAPB1475, complete sequence	38161-38183	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_KX443407	Rhodococcus hoagii strain PAM1533 plasmid PVAPB1533, complete sequence	38140-38162	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_CP036456	Streptomonospora sp. M2 plasmid phiM2, complete sequence	2515-2537	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_CP027795	Rhodococcus hoagii strain DSSKP-R-001 plasmid plas2, complete sequence	938-960	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_CP041646	Rhodococcus hoagii strain WY plasmid pWY, complete sequence	43272-43294	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NC_014247	Rhodococcus equi plasmid pVAPAMBE116, complete sequence	38452-38474	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NC_002576	Rhodococcus equi 103 plasmid p103, complete sequence	62233-62255	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NC_011150	Rhodococcus equi plasmid pVAPB1593, complete sequence	38229-38251	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NC_011151	Rhodococcus equi plasmid pVAPA1037, complete sequence	37847-37869	3	0.87
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NC_004854	Rhodococcus equi ATCC33701 plasmid pREAT701, complete sequence	62234-62256	3	0.87
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	CP054934	Nocardiopsis flavescens strain NA01583 plasmid unnamed1, complete sequence	136893-136919	3	0.889
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP023977	Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.2, complete sequence	6529-6555	3	0.889
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NC_016588	Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence	222020-222046	3	0.889
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	86046-86072	3	0.889
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_CP003988	Streptomyces sp. 769 plasmid pSGZL, complete sequence	149702-149724	4	0.826
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2209734-2209756	4	0.826
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1511796-1511818	4	0.826
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	93013-93035	4	0.826
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	MT740738	Ralstonia phage Gamede, complete genome	47514-47536	4	0.826
NZ_CP009483_8	8.4|2784790|23|NZ_CP009483|CRISPRCasFinder	2784790-2784812	23	MT740739	Ralstonia phage Gerry, complete genome	38544-38566	4	0.826
NZ_CP009483_8	8.6|2784907|23|NZ_CP009483|CRISPRCasFinder	2784907-2784929	23	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	2322591-2322613	4	0.826
NZ_CP009483_11	11.1|3373828|26|NZ_CP009483|CRISPRCasFinder	3373828-3373853	26	NC_022536	Rhizobium sp. IRBG74 plasmid IRBL74_p, complete sequence	484086-484111	4	0.846
NZ_CP009483_11	11.1|3373828|26|NZ_CP009483|CRISPRCasFinder	3373828-3373853	26	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	974316-974341	4	0.846
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP014276	Martelella sp. AD-3 plasmid unnamed1, complete sequence	24611-24637	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP045411	Roseovarius sp. THAF8 plasmid pTHAF8_a, complete sequence	141585-141611	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP045394	Roseovarius sp. THAF27 plasmid pTHAF27_a, complete sequence	142872-142898	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP045405	Roseovarius sp. THAF9 plasmid pTHAF9_a, complete sequence	137275-137301	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_LN868941	Nocardia farcinica strain NCTC11134 plasmid 4, complete sequence	44467-44493	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_LR134469	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence	102527-102553	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP031419	Nocardia farcinica strain W6977 plasmid unnamed1, complete sequence	83057-83083	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	1109099-1109125	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	615925-615951	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	969012-969038	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP025188	Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence	150248-150274	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_009468	Acidiphilium cryptum JF-5 plasmid pACRY02, complete sequence	105044-105070	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KR080198	Mycobacterium phage Cambiare, complete genome	23655-23681	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	145692-145718	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	238856-238882	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	220057-220083	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP035000	Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence	147141-147167	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	362634-362660	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP053909	Hymenobacter sp. BRD128 plasmid unnamed1, complete sequence	9303-9329	4	0.852
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP035513	Haematobacter massiliensis strain OT1 plasmid pOT1-3, complete sequence	61341-61367	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP045329	Labrenzia sp. THAF191b plasmid pTHAF191b_a, complete sequence	44890-44916	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP045345	Labrenzia sp. THAF187b plasmid pTHAF187b_a, complete sequence	360705-360731	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP045335	Labrenzia sp. THAF191a plasmid pTHAF191a_b, complete sequence	335532-335558	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP045381	Labrenzia sp. THAF35 plasmid pTHAF35_a, complete sequence	257545-257571	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	KY783914	Mycobacterium phage GardenSalsa, complete genome	21492-21518	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	MT657341	Mycobacterium phage Estes, complete genome	21668-21694	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	KY223999	Mycobacterium phage MrMagoo, complete genome	21492-21518	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP010860	Marinovum algicola DG 898 plasmid pMaD5, complete sequence	111706-111732	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP025547	Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence	261168-261194	4	0.852
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	GU936714	Synechococcus phage S-CBS2, complete genome	40756-40782	4	0.852
NZ_CP009483_21	21.1|5445934|25|NZ_CP009483|CRISPRCasFinder	5445934-5445958	25	NZ_CP045074	Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence	373525-373549	4	0.84
NZ_CP009483_21	21.1|5445934|25|NZ_CP009483|CRISPRCasFinder	5445934-5445958	25	NZ_CP013528	Rhizobium phaseoli strain R723 plasmid pRphaR723a, complete sequence	46228-46252	4	0.84
NZ_CP009483_21	21.1|5445934|25|NZ_CP009483|CRISPRCasFinder	5445934-5445958	25	NZ_CP013538	Rhizobium phaseoli strain R630 plasmid pRphaR630a, complete sequence	46229-46253	4	0.84
NZ_CP009483_21	21.1|5445934|25|NZ_CP009483|CRISPRCasFinder	5445934-5445958	25	NZ_CP013581	Rhizobium phaseoli strain N261 plasmid pRphaN261a, complete sequence	46228-46252	4	0.84
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP023738	Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence	97007-97033	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP011515	Mitsuaria sp. 7 plasmid, complete sequence	139456-139482	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	146268-146294	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	310925-310951	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	151034-151060	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	279007-279033	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	301152-301178	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_047891	Gordonia phage BENtherdunthat, complete genome	22574-22600	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5296946-5296972	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP014769	Hymenobacter sp. PAMC 26554 plasmid unnamed1, complete sequence	155147-155173	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1502146-1502172	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	CP000663	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence	118325-118351	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	228668-228694	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP031752	Rhodobacter sphaeroides strain EBL0706 plasmid p.A, complete sequence	64484-64510	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	267115-267141	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	283429-283455	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_LR134454	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence	109696-109722	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_LR134456	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence	83617-83643	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	199260-199286	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP045217	Pantoea dispersa strain BJQ0007 plasmid unnamed1, complete sequence	31233-31259	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1149354-1149380	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1440785-1440811	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1139263-1139289	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1040030-1040056	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1669754-1669780	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP033873	Caulobacter sp. FWC26 plasmid p1, complete sequence	78931-78957	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	296749-296775	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1040134-1040160	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	693562-693588	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1039831-1039857	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1039777-1039803	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KY092482	Streptomyces phage Mojorita, complete genome	33252-33278	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	JX182371	Streptomyces phage SV1, complete genome	31980-32006	5	0.815
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KY092480	Streptomyces phage Picard, complete genome	33444-33470	5	0.815
NZ_CP009483_12	12.5|3550913|27|NZ_CP009483|CRISPRCasFinder	3550913-3550939	27	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	156965-156991	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	350893-350919	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2209591-2209617	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP013503	Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence	168509-168535	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP013509	Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence	168509-168535	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP013520	Rhizobium sp. N113 plasmid pRspN113c, complete sequence	168509-168535	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP013493	Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence	168509-168535	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	303677-303703	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_KY349138	Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence	151813-151839	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NC_012529	Deinococcus deserti VCD115 plasmid 2, complete sequence	11878-11904	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP014276	Martelella sp. AD-3 plasmid unnamed1, complete sequence	24296-24322	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NC_008759	Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence	143192-143218	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	569848-569874	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	MT658802	Mycobacterium phage Aziz, complete genome	21537-21563	5	0.815
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	MF319184	Mycobacterium phage GenevaB15, complete genome	21537-21563	5	0.815
NZ_CP009483_12	12.25|3551906|27|NZ_CP009483|CRISPRCasFinder	3551906-3551932	27	NZ_CP014942	Rhodococcus sp. BH4 plasmid, complete sequence	210212-210238	5	0.815
NZ_CP009483_11	11.1|3373828|26|NZ_CP009483|CRISPRCasFinder	3373828-3373853	26	NZ_CP021405	Celeribacter manganoxidans strain DY25 plasmid pDY25-A, complete sequence	95507-95532	6	0.769
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	2013-2042	6	0.8
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	17612-17641	6	0.8
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	33212-33241	6	0.8
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP019461	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed4, complete sequence	9506-9535	6	0.8
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP019462	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed5, complete sequence	9496-9525	6	0.8
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP019463	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed6, complete sequence	9114-9143	6	0.8
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP019464	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed7, complete sequence	12263-12292	6	0.8
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	86048-86074	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	416723-416749	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP045122	Rubrobacter sp. SCSIO 52915 plasmid unnamed1, complete sequence	46169-46195	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP020948	Rhizobium sp. CIAT894 plasmid pRheCIAT894a, complete sequence	168127-168153	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP018233	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence	123014-123040	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	CP054924	Verrucosispora sp. NA02020 plasmid unnamed, complete sequence	52418-52444	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	584189-584215	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	LN907801	unidentified phage genome assembly 2P1, chromosome : 2P1	33235-33261	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KM389262	UNVERIFIED: Pseudomonas phage F_ET2439sp/Pa1651 clone ctg7180000000624 genomic sequence	5924-5950	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KM389278	UNVERIFIED: Pseudomonas phage Phi05_1400 B clone contig00006 genomic sequence	24767-24793	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	MH643778	Pseudomonas phage YMC12/01/R24, complete genome	33348-33374	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KT968832	Pseudomonas phage YMC11/11/R1836, complete genome	33447-33473	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	JF412297	EBPR siphovirus 2, partial sequence	38780-38806	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_041851	Pseudomonas phage F_HA0480sp/Pa1651, complete genome	33471-33497	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KJ477077	Pseudomonas phage JD024, complete genome	32450-32476	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	LT608331	Pseudomonas phage vB_PaeS_PcyII-40_PfII40a isolate PfII40A_reads genome assembly, chromosome: PFII40A	33187-33213	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	JX434030	Pseudomonas phage JBD5, complete genome	33892-33918	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_030918	Pseudomonas phage JBD93, complete genome	32776-32802	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	MH719192	Pseudomonas phage Ps56, complete genome	35973-35999	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	EU272037	Pseudomonas phage MP38, complete genome	33043-33069	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KM389459	UNVERIFIED: Pseudomonas phage F_ET309sp/Pa1651 clone contig00001 genomic sequence	33558-33584	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_023700	Pseudomonas phage PA1/KOR/2010, complete genome	30698-30724	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_024782	Pseudomonas phage MP48, complete genome	32987-33013	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	EU272036	Pseudomonas phage MP29, complete genome	32780-32806	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1231081-1231107	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP009293	Novosphingobium pentaromativorans US6-1 plasmid pLA4, complete sequence	328970-328996	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_LR134448	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 6, complete sequence	5342-5368	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_018746	Pseudomonas putida ND6 plasmid pND6-2, complete sequence	109093-109119	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP024895	Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence	103986-104012	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP025506	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence	73260-73286	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_011371	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG204, complete sequence	207302-207328	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_012852	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132504, complete sequence	161069-161095	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	1594882-1594908	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	141722-141748	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP022668	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence	526008-526034	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	190836-190862	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	324776-324802	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	MN961671	Pseudomonas aeruginosa strain 201330 plasmid p201330-IMP, complete sequence	17801-17827	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	MN961672	Pseudomonas aeruginosa strain PA15W plasmid pPA15W-NR, complete sequence	17799-17825	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP050088	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence	207628-207654	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KM389460	UNVERIFIED: Pseudomonas phage F_MX560sp/Pa1651 clone contig00001 genomic sequence	4918-4944	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KM389461	UNVERIFIED: Pseudomonas phage F_TK432sp/Pa1651 clone ctg7180000000005 genomic sequence	3820-3846	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KM389462	UNVERIFIED: Pseudomonas phage JBD23 clone contig00001 genomic sequence	3831-3857	6	0.778
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	KM389464	UNVERIFIED: Pseudomonas phage JBDs5 clone contig00001 genomic sequence	3840-3866	6	0.778
NZ_CP009483_12	12.17|3551534|30|NZ_CP009483|CRISPRCasFinder	3551534-3551563	30	MT952845	Microbacterium phage GardenState, complete genome	14650-14679	6	0.8
NZ_CP009483_12	12.17|3551534|30|NZ_CP009483|CRISPRCasFinder	3551534-3551563	30	MK880124	Microbacterium phage IAmGroot, complete genome	15312-15341	6	0.8
NZ_CP009483_12	12.17|3551534|30|NZ_CP009483|CRISPRCasFinder	3551534-3551563	30	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	561444-561473	6	0.8
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1210930-1210956	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1239754-1239780	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1422555-1422581	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1551738-1551764	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	647210-647236	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	4443-4469	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	396614-396640	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1173520-1173546	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1496500-1496526	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1407783-1407809	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1500378-1500404	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1674499-1674525	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1241849-1241875	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1799803-1799829	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1419988-1420014	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1242108-1242134	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	498963-498989	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1940177-1940203	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1503950-1503976	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	968697-968723	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP021373	Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence	97053-97079	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1213607-1213633	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1428802-1428828	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1460728-1460754	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1425530-1425556	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1604958-1604984	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	581155-581181	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NC_011893	Methylobacterium nodulans ORS 2060 plasmid pMNOD03, complete sequence	1007-1033	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1613118-1613144	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1389514-1389540	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	564093-564119	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NC_019957	Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence	283705-283731	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1515431-1515457	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1604925-1604951	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1479162-1479188	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1514134-1514160	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1603719-1603745	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1414266-1414292	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1479474-1479500	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1514134-1514160	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1603755-1603781	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1479162-1479188	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1414912-1414938	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1478365-1478391	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1514134-1514160	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1514134-1514160	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1514134-1514160	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1603755-1603781	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1479800-1479826	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP025513	Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence	307989-308015	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	537329-537355	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1603744-1603770	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1414288-1414314	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1421549-1421575	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1402202-1402228	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1455146-1455172	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1494336-1494362	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1511449-1511475	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1603744-1603770	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1414288-1414314	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1479473-1479499	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1481207-1481233	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1604745-1604771	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1414288-1414314	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1414288-1414314	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1603755-1603781	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1514137-1514163	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	531974-532000	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1603766-1603792	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1603567-1603593	6	0.778
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	531974-532000	6	0.778
NZ_CP009483_16	16.3|4864491|34|NZ_CP009483|PILER-CR	4864491-4864524	34	NC_042345	Phage Salvo, complete genome	21600-21633	6	0.824
NZ_CP009483_22	22.1|5907492|29|NZ_CP009483|CRISPRCasFinder	5907492-5907520	29	MN693744	Marine virus AFVG_250M180, complete genome	6920-6948	6	0.793
NZ_CP009483_22	22.1|5907492|29|NZ_CP009483|CRISPRCasFinder	5907492-5907520	29	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	1167856-1167884	6	0.793
NZ_CP009483_9	9.2|2785096|32|NZ_CP009483|CRISPRCasFinder	2785096-2785127	32	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	127147-127178	7	0.781
NZ_CP009483_9	9.2|2785096|32|NZ_CP009483|CRISPRCasFinder	2785096-2785127	32	NC_014149	Planctopirus limnophila DSM 3776 plasmid pPLIM01, complete sequence	15820-15851	7	0.781
NZ_CP009483_9	9.2|2785096|32|NZ_CP009483|CRISPRCasFinder	2785096-2785127	32	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	249425-249456	7	0.781
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	50607-50633	7	0.741
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP035002	Rhizobium acidisoli strain FH23 plasmid pRapFH23d, complete sequence	244973-244999	7	0.741
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP007050	Rhizobium leguminosarum bv. trifolii WSM1689 plasmid unnamed, complete sequence	190734-190760	7	0.741
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2040515-2040541	7	0.741
NZ_CP009483_12	12.4|3550862|27|NZ_CP009483|CRISPRCasFinder	3550862-3550888	27	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	119654-119680	7	0.741
NZ_CP009483_12	12.5|3550913|27|NZ_CP009483|CRISPRCasFinder	3550913-3550939	27	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1725853-1725879	7	0.741
NZ_CP009483_12	12.17|3551534|30|NZ_CP009483|CRISPRCasFinder	3551534-3551563	30	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	119239-119268	7	0.767
NZ_CP009483_12	12.23|3551810|27|NZ_CP009483|CRISPRCasFinder	3551810-3551836	27	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	182013-182039	7	0.741
NZ_CP009483_12	12.25|3551906|27|NZ_CP009483|CRISPRCasFinder	3551906-3551932	27	NZ_CP032828	Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence	34903-34929	7	0.741
NZ_CP009483_22	22.1|5907492|29|NZ_CP009483|CRISPRCasFinder	5907492-5907520	29	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	1260561-1260589	7	0.759
NZ_CP009483_22	22.1|5907492|29|NZ_CP009483|CRISPRCasFinder	5907492-5907520	29	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1112779-1112807	7	0.759
NZ_CP009483_22	22.1|5907492|29|NZ_CP009483|CRISPRCasFinder	5907492-5907520	29	NC_013193	Candidatus Accumulibacter phosphatis clade IIA str. UW-1 plasmid pAph01, complete sequence	160941-160969	7	0.759
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	1035884-1035915	8	0.75
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2401522-2401553	8	0.75
NZ_CP009483_9	9.2|2785096|32|NZ_CP009483|CRISPRCasFinder	2785096-2785127	32	FJ937737	Burkholderia cenocepacia phage BcepIL02, complete genome	8225-8256	8	0.75
NZ_CP009483_9	9.2|2785096|32|NZ_CP009483|CRISPRCasFinder	2785096-2785127	32	NC_012743	Burkholderia phage BcepIL02, complete genome	8225-8256	8	0.75
NZ_CP009483_12	12.17|3551534|30|NZ_CP009483|CRISPRCasFinder	3551534-3551563	30	NZ_CP020333	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM170, complete sequence	64494-64523	8	0.733
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP045296	Paenibacillus cellulositrophicus strain KACC 16577 plasmid unnamed1, complete sequence	213670-213701	9	0.719
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	441605-441636	9	0.719
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	523667-523698	9	0.719
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP047899	Pseudarthrobacter sp. YJ56 plasmid unnamed1, complete sequence	8361-8390	9	0.7
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	284321-284350	9	0.7
NZ_CP009483_12	12.3|3550808|30|NZ_CP009483|CRISPRCasFinder	3550808-3550837	30	NZ_CP015735	Arthrobacter sp. U41 plasmid unnamed3, complete sequence	12268-12297	9	0.7
NZ_CP009483_5	5.3|1062109|37|NZ_CP009483|CRISPRCasFinder	1062109-1062145	37	KJ025957	Serratia phage PS2, complete genome	153545-153581	10	0.73
NZ_CP009483_5	5.5|1062214|37|NZ_CP009483|CRISPRCasFinder	1062214-1062250	37	NZ_CP014361	Methylomonas sp. DH-1 plasmid, complete sequence	11851-11887	10	0.73
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1609319-1609350	10	0.688
NZ_CP009483_9	9.2|2785096|32|NZ_CP009483|CRISPRCasFinder	2785096-2785127	32	NZ_CP027239	Dietzia sp. oral taxon 368 strain W5195 plasmid unnamed1, complete sequence	160242-160273	10	0.688
NZ_CP009483_16	16.3|4864491|34|NZ_CP009483|PILER-CR	4864491-4864524	34	NZ_CP019438	Thioclava nitratireducens strain 25B10_4 plasmid unnamed1, complete sequence	66318-66351	10	0.706
NZ_CP009483_16	16.3|4864491|34|NZ_CP009483|PILER-CR	4864491-4864524	34	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	595297-595330	10	0.706
NZ_CP009483_16	16.3|4864491|34|NZ_CP009483|PILER-CR	4864491-4864524	34	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1537087-1537120	10	0.706
NZ_CP009483_16	16.3|4864491|34|NZ_CP009483|PILER-CR	4864491-4864524	34	NC_047910	Faecalibacterium phage FP_Epona, complete genome	18320-18353	10	0.706
NZ_CP009483_5	5.5|1062214|37|NZ_CP009483|CRISPRCasFinder	1062214-1062250	37	NZ_CP014361	Methylomonas sp. DH-1 plasmid, complete sequence	14306-14342	11	0.703
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	76896-76927	11	0.656
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1056098-1056129	11	0.656
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1525045-1525076	11	0.656
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	68158-68189	11	0.656
NZ_CP009483_7	7.1|1937389|32|NZ_CP009483|CRISPRCasFinder	1937389-1937420	32	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	607322-607353	11	0.656

1. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP040723 (Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgacgccgcccac	Protospacer
*********************

2. spacer 1.2|466019|21|NZ_CP009483|CRISPRCasFinder matches to NZ_AP018921 (Pseudonocardia autotrophica strain NBRC 12743 plasmid pPA12743CP, complete sequence) position: , mismatch: 1, identity: 0.952

ccgtattggccgggctgggcc	CRISPR spacer
ccgtactggccgggctgggcc	Protospacer
*****.***************

3. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NC_019407 (Caulobacter phage CcrMagneto, complete genome) position: , mismatch: 1, identity: 0.957

agcgggcggcgccggcggctggc	CRISPR spacer
ggcgggcggcgccggcggctggc	Protospacer
.**********************

4. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 1, identity: 0.952

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgccgacgccgccggg	Protospacer
******************** 

5. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to NZ_LR134447 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 5, complete sequence) position: , mismatch: 1, identity: 0.952

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgcctacgccgccggt	Protospacer
********* ***********

6. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to NC_008758 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP02, complete sequence) position: , mismatch: 1, identity: 0.952

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgccgaagccgccggt	Protospacer
*********** *********

7. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 1, identity: 0.952

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgccgccgccgccggt	Protospacer
********** **********

8. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 1, identity: 0.952

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgccgccgccgccggt	Protospacer
********** **********

9. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
gccgccgccgacgccgcccac	Protospacer
.********************

10. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgacgccgccgac	Protospacer
****************** **

11. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP016820 (Rhodococcus sp. p52 plasmid pDF02, complete sequence) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
actgccgccgacgccgcccac	Protospacer
**.******************

12. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to MN908693 (Gordonia phage AnClar, complete genome) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgacgccgccgac	Protospacer
****************** **

13. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to MK801725 (Gordonia phage Yago84, complete genome) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgacgccgccgac	Protospacer
****************** **

14. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgacgccgccgac	Protospacer
****************** **

15. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP020811 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgacgccgaccac	Protospacer
**************** ****

16. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP020811 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgacgccgaccac	Protospacer
**************** ****

17. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP023713 (Rhodococcus ruber strain YC-YT1 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgacgccgacgccgcccac	Protospacer
**** ****************

18. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP053567 (Pseudonocardia sp. Gen01 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgccgccgcccac	Protospacer
********** **********

19. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to MH105773 (Vibrio phage Rostov-6, complete genome) position: , mismatch: 1, identity: 0.952

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgccgccgcccac	Protospacer
********** **********

20. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP035092 (Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.952

ggggccgctgtcgccgccggt	CRISPR spacer
ggggctgctgtcgccgccggt	Protospacer
*****.***************

21. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to NC_008688 (Paracoccus denitrificans PD1222 plasmid 1, complete sequence) position: , mismatch: 1, identity: 0.952

ggggccgctgtcgccgccggt	CRISPR spacer
ggggctgctgtcgccgccggt	Protospacer
*****.***************

22. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 1, identity: 0.952

ggggccgctgtcgccgccggt	CRISPR spacer
ggggctgctgtcgccgccggt	Protospacer
*****.***************

23. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 1, identity: 0.952

ggggccgctgtcgccgccggt	CRISPR spacer
ggggccgctgtcggcgccggt	Protospacer
************* *******

24. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to AF068845 (Mycobacteriophage TM4, complete genome) position: , mismatch: 1, identity: 0.952

ggggccgctgtcgccgccggt	CRISPR spacer
ggtgccgctgtcgccgccggt	Protospacer
** ******************

25. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to KC787101 (Mycobacterium phage 33D, partial genome) position: , mismatch: 1, identity: 0.952

ggggccgctgtcgccgccggt	CRISPR spacer
ggtgccgctgtcgccgccggt	Protospacer
** ******************

26. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to NC_003387 (Mycobacterium phage TM4, complete genome) position: , mismatch: 1, identity: 0.952

ggggccgctgtcgccgccggt	CRISPR spacer
ggtgccgctgtcgccgccggt	Protospacer
** ******************

27. spacer 12.20|3551678|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP024936 (Paraburkholderia graminis strain PHS1 plasmid pPHS1_P, complete sequence) position: , mismatch: 1, identity: 0.952

agcggcgccaggccgctcgag	CRISPR spacer
agcggcgccacgccgctcgag	Protospacer
********** **********

28. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
tccgccaccgccgccgccggt	Protospacer
 ********************

29. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgga	Protospacer
******************** 

30. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgcgggt	Protospacer
***************** ***

31. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgacggt	Protospacer
**************** ****

32. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

33. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

34. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to CP021185 (Sphingomonas wittichii DC-6 plasmid pDC04, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

35. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

36. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgcccgt	Protospacer
****************** **

37. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

38. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

39. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

40. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

41. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP018224 (Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL3, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

42. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013267 (Sphingobium baderi strain DE-13 plasmid pDE3, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

43. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

44. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP041019 (Sphingobium fuliginis ATCC 27551 plasmid pSF2, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

45. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccacctccgccgccggt	Protospacer
********* ***********

46. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

47. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccactgccgccgccggt	Protospacer
********.************

48. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KP027207 (Mycobacterium phage Chandler, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

49. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MN096360 (Mycobacterium phage Rita1961, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

50. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MG839014 (Mycobacterium phage RagingRooster, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

51. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KJ194581 (Mycobacterium phage Audrey, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

52. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KR080203 (Mycobacterium phage OrangeOswald, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

53. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MH513976 (Mycobacterium phage Morty007, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

54. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MH051265 (Mycobacterium phage Yahalom, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

55. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MH316565 (Mycobacterium phage Mortcellus, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

56. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MT310871 (Mycobacterium phage Jackstina, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

57. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MK359357 (Mycobacterium phage RomaT, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

58. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to JF704095 (Mycobacterium phage Daisy, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

59. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to EU816589 (Mycobacterium phage Phaedrus, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

60. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MN096359 (Mycobacterium phage Obutu, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

61. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MK061414 (Mycobacterium phage Marley1013, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

62. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MT952851 (Mycobacterium phage Gervas, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

63. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MG925353 (Mycobacterium phage Nozo, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

64. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_019410 (Caulobacter phage CcrKarma, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccgccgccgccgccggt	Protospacer
******.**************

65. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KJ194584 (Mycobacterium phage Heathcliff, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

66. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MN444872 (Mycobacterium phage SynergyX, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

67. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MH576977 (Mycobacterium phage Tydolla, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

68. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MG925338 (Mycobacterium phage ChaChing, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

69. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_023742 (Mycobacterium phage Akoma, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

70. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MG920059 (Mycobacterium phage Baloo, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

71. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_019407 (Caulobacter phage CcrMagneto, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccgccgccgccgccggt	Protospacer
******.**************

72. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_023686 (Mycobacterium phage Gadjet, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

73. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KR080205 (Mycobacterium phage Corofin, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

74. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_041965 (Mycobacterium phage Athena, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

75. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MT310892 (Mycobacterium phage Compostia, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

76. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to JN699018 (Mycobacterium phage Kamiyu, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

77. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_012027 (Mycobacterium phage Phlyer, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

78. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MN444873 (Mycobacterium phage Abinghost, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

79. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_019411 (Caulobacter phage CcrSwift, complete genome) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccgccgccgccgccggt	Protospacer
******.**************

80. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013298 (Arthrobacter sp. YC-RL1 plasmid unnamed 1, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgcggccggt	Protospacer
************** ******

81. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP010955 (Sphingobium sp. YBL2 plasmid 1pYBL2-1, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

82. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_017081 (Phycisphaera mikurensis NBRC 102666 plasmid pPSMK1, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccaccggt	Protospacer
***************.*****

83. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccaccgccggt	Protospacer
************.********

84. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccacctccgccgccggt	Protospacer
********* ***********

85. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP054615 (Azospirillum oryzae strain KACC 14407 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgcccccggt	Protospacer
*************** *****

86. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_014007 (Sphingobium japonicum UT26S plasmid pCHQ1, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

87. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP047221 (Sphingobium yanoikuyae strain YC-JY1 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.952

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtt	Protospacer
******************* *

88. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP054025 (Rhizobium sp. JKLM12A2 plasmid pPR12A204, complete sequence) position: , mismatch: 1, identity: 0.952

gaaaccgccgccgccgccgta	CRISPR spacer
gaagccgccgccgccgccgta	Protospacer
***.*****************

89. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP054034 (Rhizobium sp. JKLM13E plasmid pPR13E03, complete sequence) position: , mismatch: 1, identity: 0.952

gaaaccgccgccgccgccgta	CRISPR spacer
gaagccgccgccgccgccgta	Protospacer
***.*****************

90. spacer 5.1|1062004|22|NZ_CP009483|CRISPRCasFinder matches to NC_015595 (Sphingobium chlorophenolicum L-1 plasmid pSPHCH01, complete sequence) position: , mismatch: 2, identity: 0.909

accgaagccgacgttgctactc	CRISPR spacer
tccgaagccgacgttgcgactc	Protospacer
 **************** ****

91. spacer 5.6|1062274|22|NZ_CP009483|CRISPRCasFinder matches to NC_022044 (Paracoccus aminophilus JCM 7686 plasmid pAMI6, complete sequence) position: , mismatch: 2, identity: 0.909

gccgctgcccaagttgaacgag	CRISPR spacer
accgctgcccaaattgaacgag	Protospacer
.***********.*********

92. spacer 6.2|1524866|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP031358 (Erythrobacter aureus strain YH-07 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.913

agggtgccggcgacggtatcccg	CRISPR spacer
agcgtgccggcgacgttatcccg	Protospacer
** ************ *******

93. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NC_019410 (Caulobacter phage CcrKarma, complete genome) position: , mismatch: 2, identity: 0.913

agcgggcggcgccggcggctggc	CRISPR spacer
ggcgggcggctccggcggctggc	Protospacer
.********* ************

94. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NC_019411 (Caulobacter phage CcrSwift, complete genome) position: , mismatch: 2, identity: 0.913

agcgggcggcgccggcggctggc	CRISPR spacer
ggcgggcggctccggcggctggc	Protospacer
.********* ************

95. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_LR134459 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 17, complete sequence) position: , mismatch: 2, identity: 0.913

agcgggcggcgccggcggctggc	CRISPR spacer
agcgggcggcgcctgctgctggc	Protospacer
************* ** ******

96. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to MH617140 (Microviridae sp. isolate ctce707, complete genome) position: , mismatch: 2, identity: 0.913

agcgggcggcgccggcggctggc	CRISPR spacer
agcgggcggcgccggccgccggc	Protospacer
**************** **.***

97. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to CP047389 (Agrobacterium sp. CGMCC 11546 plasmid pA) position: , mismatch: 2, identity: 0.913

cgacgccggcgccagcggcacct	CRISPR spacer
cgacgccggcgccagccgctcct	Protospacer
**************** ** ***

98. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to CP047389 (Agrobacterium sp. CGMCC 11546 plasmid pA) position: , mismatch: 2, identity: 0.913

cgacgccggcgccagcggcacct	CRISPR spacer
cgacgccggcgccagccgctcct	Protospacer
**************** ** ***

99. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP023738 (Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence) position: , mismatch: 2, identity: 0.913

cgacgccggcgccagcggcacct	CRISPR spacer
cgacggcggcgcgagcggcacct	Protospacer
***** ****** **********

100. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP051182 (Thalassobius gelatinovorus strain NEB572 plasmid pAge77, complete sequence) position: , mismatch: 2, identity: 0.926

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggtgccgcccagcccgtcttcgccgcc	Protospacer
********* ******.**********

101. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 2, identity: 0.905

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgccgacgccgccgtg	Protospacer
*******************  

102. spacer 12.15|3551444|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP040765 (Paracoccus sp. 2251 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.905

gccaccgccgacgccgccggt	CRISPR spacer
gccaccgccgacgccgccgag	Protospacer
*******************. 

103. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccgccgacgccgcccac	CRISPR spacer
cacgccgccgacgccgcccac	Protospacer
  *******************

104. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NC_005307 (Gordonia westfalica strain DSM44215T plasmid pKB1 complete genome) position: , mismatch: 2, identity: 0.905

accgccgccgacgccgcccac	CRISPR spacer
accgccgccgacgccgccctg	Protospacer
*******************  

105. spacer 12.18|3551588|21|NZ_CP009483|CRISPRCasFinder matches to NZ_AP014811 (Methylorubrum populi strain P-1M plasmid pMPPM02, complete sequence) position: , mismatch: 2, identity: 0.905

accgccgccgacgccgcccac	CRISPR spacer
gccgccgccgacgccgcccat	Protospacer
.*******************.

106. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 2, identity: 0.905

ggggccgctgtcgccgccggt	CRISPR spacer
cgggccgctgtcgccgccggc	Protospacer
 *******************.

107. spacer 12.19|3551633|21|NZ_CP009483|CRISPRCasFinder matches to MF324914 (Mycobacterium phage Krueger, complete genome) position: , mismatch: 2, identity: 0.905

ggggccgctgtcgccgccggt	CRISPR spacer
ccggccgctgtcgccgccggt	Protospacer
  *******************

108. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to AM261282 (Uncultured bacterium IncP-1 plasmid pKJK5 complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

109. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045074 (Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccgga	Protospacer
.******************* 

110. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP026382 (Sphingopyxis sp. MG plasmid pCMS1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

111. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP015279 (Mycobacterium chimaera strain DSM 44623 plasmid unnamed 1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

112. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP006570 (Sodalis praecaptivus strain HS1 plasmid pHS1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

113. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP028340 (Thauera aromatica K172 plasmid pKJK172, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

114. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
cccgccaccgccgccgccggc	Protospacer
 *******************.

115. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

116. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP007256 (Rhodococcus erythropolis R138 plasmid pCRE138, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

117. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KC964605 (Uncultured bacterium plasmid pMLUA1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

118. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KC964606 (Uncultured bacterium plasmid pMLUA3, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

119. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KC964607 (Uncultured bacterium plasmid pMLUA4, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

120. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_MN366356 (Bacterium plasmid pALTS27, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

121. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_MN366360 (Bacterium plasmid pALTS32, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

122. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgac	Protospacer
*******************..

123. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to AP014018 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C106A-MedDCM-OCT-S35-C77, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

124. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_028802 (Mycobacterium phage UnionJack, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

125. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MK524490 (Mycobacterium phage Donny, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccgga	Protospacer
.******************* 

126. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MF919502 (Mycobacterium phage Demsculpinboyz, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgta	Protospacer
*******************  

127. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KJ567044 (Mycobacterium phage EmpTee, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

128. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to AY129336 (Mycobacteriophage Che9d, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgta	Protospacer
*******************  

129. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_028828 (Mycobacterium phage TheloniousMonk, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgta	Protospacer
*******************  

130. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MH669014 (Mycobacterium phage Spikelee, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgta	Protospacer
*******************  

131. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KR080198 (Mycobacterium phage Cambiare, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccggc	Protospacer
.*******************.

132. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to AY848685 (Enterobacteria phage PR3, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

133. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MT889380 (Mycobacterium phage Coco12, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgta	Protospacer
*******************  

134. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KR080206 (Mycobacterium phage ShedlockHolmes, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgag	Protospacer
*******************. 

135. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_023698 (Mycobacterium phage Avani, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgta	Protospacer
*******************  

136. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to JN699007 (Mycobacterium phage Acadian, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccgga	Protospacer
.******************* 

137. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to AY848684 (Enterobacteria phage L17, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

138. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MG812486 (Mycobacterium phage Acme, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

139. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_028791 (Mycobacterium phage MOOREtheMARYer, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccggc	Protospacer
.*******************.

140. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_028791 (Mycobacterium phage MOOREtheMARYer, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

141. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MN693628 (Marine virus AFVG_250M875, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccggg	Protospacer
.******************* 

142. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MG925349 (Mycobacterium phage Mendokysei, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccggg	Protospacer
.******************* 

143. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MT889381 (Mycobacterium phage Suigeneris, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccgga	Protospacer
.******************* 

144. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KJ194580 (Mycobacterium phage Badfish, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

145. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_042323 (Mycobacterium virus Mozy, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

146. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MT114167 (Mycobacterium phage Phanphagia, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgta	Protospacer
*******************  

147. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to KM347889 (Mycobacterium phage BuzzLyseyear, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgta	Protospacer
*******************  

148. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to JF712866 (Vibrio phage phiVC8, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

149. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MK061411 (Mycobacterium phage Faze9, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgca	Protospacer
*******************  

150. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

151. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP015268 (Mycobacterium chimaera strain ZUERICH-2 plasmid unnamed 1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

152. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

153. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

154. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgac	Protospacer
*******************..

155. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccggc	Protospacer
.*******************.

156. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to JQ004406 (Uncultured bacterium plasmid pHH128, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

157. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to JQ004407 (Uncultured bacterium plasmid pHH3408, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

158. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to JQ004408 (Uncultured bacterium plasmid pHH3414, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

159. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to JQ004409 (Uncultured bacterium plasmid pKS77, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

160. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP014311 (Burkholderia sp. PAMC 26561 plasmid unnamed4, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

161. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgtc	Protospacer
******************* .

162. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to AP014019 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C106A-MedDCM-OCT-S39-C83, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
accgccaccgccgccgccgcc	Protospacer
******************* .

163. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MN694400 (Marine virus AFVG_250M1011, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccggg	Protospacer
.******************* 

164. spacer 12.21|3551723|21|NZ_CP009483|CRISPRCasFinder matches to MN994497 (Phage NBEco003, complete genome) position: , mismatch: 2, identity: 0.905

accgccaccgccgccgccggt	CRISPR spacer
gccgccaccgccgccgccggc	Protospacer
.*******************.

165. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

166. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

167. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

168. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

169. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

170. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

171. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

172. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

173. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

174. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

175. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to MN103533 (Mycobacterium phage Weirdo19, complete genome) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgcc	Protospacer
*******************. 

176. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to JX100810 (Caulobacter phage CcrColossus, complete genome) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgcg	Protospacer
*******************..

177. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to MH588547 (Caulobacter phage CcrSC, complete genome) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgcg	Protospacer
*******************..

178. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgcc	Protospacer
*******************. 

179. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

180. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

181. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

182. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

183. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

184. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

185. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

186. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

187. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

188. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

189. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgat	Protospacer
*******************  

190. spacer 12.24|3551861|21|NZ_CP009483|CRISPRCasFinder matches to NZ_CP004394 (Celeribacter indicus strain P73 plasmid pP73A, complete sequence) position: , mismatch: 2, identity: 0.905

gaaaccgccgccgccgccgta	CRISPR spacer
gaaaccgccgccgccgccgcg	Protospacer
*******************..

191. spacer 3.1|1061638|22|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 3, identity: 0.864

accgaagctggtgttcgagttg	CRISPR spacer
gccgaagctggtgttcgagtct	Protospacer
.*******************. 

192. spacer 4.1|1061788|22|NZ_CP009483|CRISPRCasFinder matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.864

cccgaagcccgtgttccccacg	CRISPR spacer
tgtgaagcccgtgttccccacg	Protospacer
. .*******************

193. spacer 6.1|1524818|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP033971 (Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.87

taccggccggcaacggcggcgca	CRISPR spacer
caccggccggcaacggctgcgcg	Protospacer
.**************** ****.

194. spacer 6.1|1524818|23|NZ_CP009483|CRISPRCasFinder matches to NC_011758 (Methylorubrum extorquens CM4 plasmid pCMU01, complete sequence) position: , mismatch: 3, identity: 0.87

taccggccggcaacggcggcgca	CRISPR spacer
gaccggccggctacggcggcgcg	Protospacer
 ********** **********.

195. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KM017071 (Sphingomonas sp. JE1 plasmid pJE1, complete sequence) position: , mismatch: 3, identity: 0.87

agcgggcggcgccggcggctggc	CRISPR spacer
agccggcggcgccggcggctgtg	Protospacer
*** *****************  

196. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 3, identity: 0.87

agcgggcggcgccggcggctggc	CRISPR spacer
agcgggcggcgccggcggatgag	Protospacer
****************** **. 

197. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP023524 (Burkholderia gladioli pv. gladioli strain FDAARGOS_389 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.87

agcgggcggcgccggcggctggc	CRISPR spacer
cgcgcgcggcgccggcggctggg	Protospacer
 *** ***************** 

198. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to CP000663 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence) position: , mismatch: 3, identity: 0.87

agcgggcggcgccggcggctggc	CRISPR spacer
tgcgggcggcgccggcggctcgg	Protospacer
 ******************* * 

199. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP053345 (Herbiconiux sp. SALV-R1 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.87

agcgggcggcgccggcggctggc	CRISPR spacer
ggcgggcggagccggcggctggg	Protospacer
.******** ************ 

200. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to MH588544 (Caulobacter phage CcrBL10, complete genome) position: , mismatch: 3, identity: 0.87

agcgggcggcgccggcggctggc	CRISPR spacer
gacgggcggcgcgggcggctggc	Protospacer
..********** **********

201. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NC_048047 (Caulobacter phage CcrBL9, complete genome) position: , mismatch: 3, identity: 0.87

agcgggcggcgccggcggctggc	CRISPR spacer
gacgggcggcgcgggcggctggc	Protospacer
..********** **********

202. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NC_048047 (Caulobacter phage CcrBL9, complete genome) position: , mismatch: 3, identity: 0.87

agcgggcggcgccggcggctggc	CRISPR spacer
ctcgggcggcgcgggcggctggc	Protospacer
  ********** **********

203. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443392 (Rhodococcus hoagii strain PAM1340 plasmid pVAPA1340, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

204. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443389 (Rhodococcus hoagii strain PAM1357 plasmid pVAPA1357, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

205. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443403 (Rhodococcus hoagii strain PAM2288 plasmid pVAPA2288, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

206. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443388 (Rhodococcus hoagii strain PAM1216 plasmid pVAPA1216, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

207. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443393 (Rhodococcus hoagii strain PAM1637 plasmid pVAPA1637, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

208. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443402 (Rhodococcus hoagii strain PAM2285 plasmid pVAPA2285, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

209. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443390 (Rhodococcus hoagii strain PAM1422 plasmid pVAPA1422, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

210. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443395 (Rhodococcus hoagii strain PAM2282 plasmid pVAPA2282, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

211. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443404 (Rhodococcus hoagii strain PAM2287 plasmid pVAPA2287, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

212. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443405 (Rhodococcus hoagii strain PAM2279 plasmid pVAPA2279, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

213. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443391 (Rhodococcus hoagii strain PAM1600 plasmid pVAPA1600, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

214. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443394 (Rhodococcus hoagii strain PAM1643 plasmid pVAPA1643, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

215. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443396 (Rhodococcus hoagii strain PAM1271 plasmid pVAPA1271, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

216. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443406 (Rhodococcus hoagii strain PAM1413 plasmid pVAPB1413, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

217. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443397 (Rhodococcus hoagii strain PAM1475 plasmid pVAPB1475, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

218. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_KX443407 (Rhodococcus hoagii strain PAM1533 plasmid PVAPB1533, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

219. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP036456 (Streptomonospora sp. M2 plasmid phiM2, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
cgccgccggcgccagcggcacgc	Protospacer
** ****************** .

220. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP027795 (Rhodococcus hoagii strain DSSKP-R-001 plasmid plas2, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

221. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP041646 (Rhodococcus hoagii strain WY plasmid pWY, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

222. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NC_014247 (Rhodococcus equi plasmid pVAPAMBE116, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

223. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NC_002576 (Rhodococcus equi 103 plasmid p103, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

224. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NC_011150 (Rhodococcus equi plasmid pVAPB1593, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

225. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NC_011151 (Rhodococcus equi plasmid pVAPA1037, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

226. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NC_004854 (Rhodococcus equi ATCC33701 plasmid pREAT701, complete sequence) position: , mismatch: 3, identity: 0.87

cgacgccggcgccagcggcacct	CRISPR spacer
tgacgccggcgccaacggcaccc	Protospacer
.*************.*******.

227. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to CP054934 (Nocardiopsis flavescens strain NA01583 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.889

--ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ccggtg--gccgagctcgccttcgccgcc	Protospacer
  ****  *******.*************

228. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP023977 (Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.2, complete sequence) position: , mismatch: 3, identity: 0.889

ggtcccgccggccccgccgatgccacc	CRISPR spacer
gatcccgtcggccccgccgatgccccc	Protospacer
*.*****.**************** **

229. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NC_016588 (Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence) position: , mismatch: 3, identity: 0.889

ggtcccgccggccccgccgatgccacc	CRISPR spacer
gctcccgccgcccccgccgatgccgcc	Protospacer
* ******** *************.**

230. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 3, identity: 0.889

ggtcccgccggccccgccgatgccacc-	CRISPR spacer
ggacccgccggccccgccgat-ccgccg	Protospacer
** ****************** **.** 

231. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP003988 (Streptomyces sp. 769 plasmid pSGZL, complete sequence) position: , mismatch: 4, identity: 0.826

agcgggcggcgccggcggctggc	CRISPR spacer
ccggggcggcgccggcggctggt	Protospacer
   *******************.

232. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.826

agcgggcggcgccggcggctggc	CRISPR spacer
agcgggcggcgccggcggcgatg	Protospacer
******************* .  

233. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 4, identity: 0.826

agcgggcggcgccggcggctggc	CRISPR spacer
cgcgggcggcgccggcggcttcg	Protospacer
 *******************   

234. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.826

agcgggcggcgccggcggctggc	CRISPR spacer
gttgggcggcgccggcggctgga	Protospacer
. .******************* 

235. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to MT740738 (Ralstonia phage Gamede, complete genome) position: , mismatch: 4, identity: 0.826

agcgggcggcgccggcggctggc	CRISPR spacer
cgcgggcggcgccggcggctccg	Protospacer
 *******************   

236. spacer 8.4|2784790|23|NZ_CP009483|CRISPRCasFinder matches to MT740739 (Ralstonia phage Gerry, complete genome) position: , mismatch: 4, identity: 0.826

agcgggcggcgccggcggctggc	CRISPR spacer
cgcgggcggcgccggcggctccg	Protospacer
 *******************   

237. spacer 8.6|2784907|23|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 4, identity: 0.826

cgacgccggcgccagcggcacct	CRISPR spacer
cgacgccggcgccagcggctggc	Protospacer
*******************   .

238. spacer 11.1|3373828|26|NZ_CP009483|CRISPRCasFinder matches to NC_022536 (Rhizobium sp. IRBG74 plasmid IRBL74_p, complete sequence) position: , mismatch: 4, identity: 0.846

ttgccgtatcgagcgtgcggtggtgc	CRISPR spacer
cggccgtttcgagcgtgcggcggtgc	Protospacer
. ***** ************.*****

239. spacer 11.1|3373828|26|NZ_CP009483|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 4, identity: 0.846

ttgccgtatcgagcgtgcggtggtgc	CRISPR spacer
attccctatcgagcgtgcggtggtcc	Protospacer
 * ** ****************** *

240. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP014276 (Martelella sp. AD-3 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
attgccgccggccccgccttcgccgcc	Protospacer
. ********. ***************

241. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045411 (Roseovarius sp. THAF8 plasmid pTHAF8_a, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgtgccgccaaggccgccttcgccgca	Protospacer
 ********.** ************* 

242. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045394 (Roseovarius sp. THAF27 plasmid pTHAF27_a, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgtgccgccaaggccgccttcgccgca	Protospacer
 ********.** ************* 

243. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045405 (Roseovarius sp. THAF9 plasmid pTHAF9_a, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgtgccgccaaggccgccttcgccgca	Protospacer
 ********.** ************* 

244. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_LN868941 (Nocardia farcinica strain NCTC11134 plasmid 4, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gccgccgccgagaacgccttcgccgcc	Protospacer
* .*********  *************

245. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_LR134469 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gtggccggcgagcccgcctccgccgcc	Protospacer
*  **** ***********.*******

246. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP031419 (Nocardia farcinica strain W6977 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gccgccgccgagaacgccttcgccgcc	Protospacer
* .*********  *************

247. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gacgccgtcgagcccgccgtcgccgcc	Protospacer
*..****.********** ********

248. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gctgccgtagagcccgccttcgccgca	Protospacer
* *****. ***************** 

249. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gaggccgccaagcgcgccttcgccgcc	Protospacer
*. ******.*** *************

250. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP025188 (Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcggcggccgaggccgccttcgccgcc	Protospacer
*  ** ****** **************

251. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_009468 (Acidiphilium cryptum JF-5 plasmid pACRY02, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
agggccgccgaggccgctttcgccgcc	Protospacer
.* ********* ****.*********

252. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KR080198 (Mycobacterium phage Cambiare, complete genome) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gccgccgccgcgcccgccatcgccgcc	Protospacer
* .******* ******* ********

253. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
agcgccgccgcgcccgcctacgccgcc	Protospacer
.*.******* ******** *******

254. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgcgccgccgagccggacttcgccgcc	Protospacer
 *.*********** * **********

255. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gccgccgacgagcccgcctccgccgcc	Protospacer
* .**** ***********.*******

256. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP035000 (Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gacgccgtcgagcccgccgtcgccgcc	Protospacer
*..****.********** ********

257. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggcgatgtcgagcccgccttcgccgcc	Protospacer
**.* .*.*******************

258. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP053909 (Hymenobacter sp. BRD128 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggccccgccgagcccgcccgcgccgcc	Protospacer
**. **************. *******

259. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP035513 (Haematobacter massiliensis strain OT1 plasmid pOT1-3, complete sequence) position: , mismatch: 4, identity: 0.852

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggtgccgccgaaaccgccttcgcgggc	Protospacer
***********. ********** * *

260. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045329 (Labrenzia sp. THAF191b plasmid pTHAF191b_a, complete sequence) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
attcccgccggacccgccggtgccacc	Protospacer
. ********* *******.*******

261. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045345 (Labrenzia sp. THAF187b plasmid pTHAF187b_a, complete sequence) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
attcccgccggacccgccggtgccacc	Protospacer
. ********* *******.*******

262. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045335 (Labrenzia sp. THAF191a plasmid pTHAF191a_b, complete sequence) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
attcccgccggacccgccggtgccacc	Protospacer
. ********* *******.*******

263. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045381 (Labrenzia sp. THAF35 plasmid pTHAF35_a, complete sequence) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
attcccgccggacccgccggtgccacc	Protospacer
. ********* *******.*******

264. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to KY783914 (Mycobacterium phage GardenSalsa, complete genome) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acttccgccagccccgccgatgccacc	Protospacer
. *.*****.*****************

265. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to MT657341 (Mycobacterium phage Estes, complete genome) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acttccgccagccccgccgatgccacc	Protospacer
. *.*****.*****************

266. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to KY223999 (Mycobacterium phage MrMagoo, complete genome) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acttccgccagccccgccgatgccacc	Protospacer
. *.*****.*****************

267. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP010860 (Marinovum algicola DG 898 plasmid pMaD5, complete sequence) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ggtcacgccggcccggccgatgccgct	Protospacer
**** ********* *********.*.

268. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP025547 (Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
gctaccgccggccccgccgttgccgcc	Protospacer
* * *************** ****.**

269. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to GU936714 (Synechococcus phage S-CBS2, complete genome) position: , mismatch: 4, identity: 0.852

ggtcccgccggccccgccgatgccacc	CRISPR spacer
gtttccgccggcaccgccgttgccacc	Protospacer
* *.******** ****** *******

270. spacer 21.1|5445934|25|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045074 (Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

tctgatggccgggctcctcaccggg	CRISPR spacer
gctgctggccgggatcctcaccggc	Protospacer
 *** ******** ********** 

271. spacer 21.1|5445934|25|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013528 (Rhizobium phaseoli strain R723 plasmid pRphaR723a, complete sequence) position: , mismatch: 4, identity: 0.84

tctgatggccgggctcctcaccggg	CRISPR spacer
gctgctggccgtgctcctcaccggc	Protospacer
 *** ****** ************ 

272. spacer 21.1|5445934|25|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013538 (Rhizobium phaseoli strain R630 plasmid pRphaR630a, complete sequence) position: , mismatch: 4, identity: 0.84

tctgatggccgggctcctcaccggg	CRISPR spacer
gctgctggccgtgctcctcaccggc	Protospacer
 *** ****** ************ 

273. spacer 21.1|5445934|25|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013581 (Rhizobium phaseoli strain N261 plasmid pRphaN261a, complete sequence) position: , mismatch: 4, identity: 0.84

tctgatggccgggctcctcaccggg	CRISPR spacer
gctgctggccgtgctcctcaccggc	Protospacer
 *** ****** ************ 

274. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP023738 (Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ttatccgccgagccggccttcgccgcc	Protospacer
    ********** ************

275. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP011515 (Mitsuaria sp. 7 plasmid, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctcgccgccctgcccgccttcgccgcc	Protospacer
  .******  ****************

276. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctcgccgccgagccggccttcgccggc	Protospacer
  .*********** ********** *

277. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
tacgccgcctaccccgccttcgccgcc	Protospacer
 ..****** * ***************

278. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
acagccgccgttcccgccttcgccgcc	Protospacer
.  *******  ***************

279. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctggccgccgggccggccttcgccgcc	Protospacer
   *******.*** ************

280. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cccgccgccgagcccggcttcgtcgcc	Protospacer
  .************* *****.****

281. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_047891 (Gordonia phage BENtherdunthat, complete genome) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
tccgccaccgagcccgcctgcgccgcc	Protospacer
  .***.************ *******

282. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
atcgccgccgaccccgccctcgccgcc	Protospacer
. .******** ******.********

283. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP014769 (Hymenobacter sp. PAMC 26554 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gccctcgctgagcccgccttcgccgcc	Protospacer
* . .***.******************

284. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
tacgccgcctaccccgccttcgccgcc	Protospacer
 ..****** * ***************

285. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to CP000663 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctggcggccgagcccgccatcgccgcc	Protospacer
   ** ************ ********

286. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gactacgccgagcccgtcttcgccgcc	Protospacer
*..  ***********.**********

287. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP031752 (Rhodobacter sphaeroides strain EBL0706 plasmid p.A, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctggcggccgagcccgccatcgccgcc	Protospacer
   ** ************ ********

288. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cccggcgccgggcccgccttcgccgcc	Protospacer
  .* *****.****************

289. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgacccgccgagcccggcctcgccgcc	Protospacer
 *  ************ *.********

290. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_LR134454 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
tgggccgccgaggccgccgtcgccgcg	Protospacer
 * ********* ***** ******* 

291. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_LR134456 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gacgccgccgagccggcctacgccgcg	Protospacer
*..*********** **** ****** 

292. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gagaccgacgagcccgacttcgccgcc	Protospacer
*. .*** ******** **********

293. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045217 (Pantoea dispersa strain BJQ0007 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcggccgccgagcccgcctgcgcggcg	Protospacer
*  **************** *** ** 

294. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcagccggcgagcacgccttcgccgcg	Protospacer
*  **** ***** ************ 

295. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgcgccgccgagcccgccttcggccca	Protospacer
 *.******************* * * 

296. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcagccggcgagcacgccttcgccgcg	Protospacer
*  **** ***** ************ 

297. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcagccggcgagcacgccttcgccgcg	Protospacer
*  **** ***** ************ 

298. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcgaccgccctgcccgccttcgccgcc	Protospacer
*  .*****  ****************

299. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP033873 (Caulobacter sp. FWC26 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gttctggctgagcccgccttcgccgcc	Protospacer
* * . **.******************

300. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
aatgccgccgcgcccgcctacgccgac	Protospacer
..******** ******** ***** *

301. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcagccggcgagcacgccttcgccgcg	Protospacer
*  **** ***** ************ 

302. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcagccggcgagcacgccttcgccgcg	Protospacer
*  **** ***** ************ 

303. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcagccggcgagcacgccttcgccgcg	Protospacer
*  **** ***** ************ 

304. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gcagccggcgagcacgccttcgccgcg	Protospacer
*  **** ***** ************ 

305. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KY092482 (Streptomyces phage Mojorita, complete genome) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgcaccgccgaggccgccctcgccgcc	Protospacer
 *..******** *****.********

306. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to JX182371 (Streptomyces phage SV1, complete genome) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgcaccgccgaggccgccctcgccgcc	Protospacer
 *..******** *****.********

307. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KY092480 (Streptomyces phage Picard, complete genome) position: , mismatch: 5, identity: 0.815

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgcaccgccgaggccgccctcgccgcc	Protospacer
 *..******** *****.********

308. spacer 12.5|3550913|27|NZ_CP009483|CRISPRCasFinder matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 5, identity: 0.815

ggcgctacccgcgccggttccgggttg	CRISPR spacer
ggcgctacctgcgccggtgccgggact	Protospacer
*********.******** ***** . 

309. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ggccccgccggccccgccgttgccgat	Protospacer
**.**************** ****. .

310. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
tgcgccgccagccccgccgttgccacc	Protospacer
 *. *****.********* *******

311. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013503 (Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acccgcgccggccccgccgatcccacc	Protospacer
. .* **************** *****

312. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013509 (Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acccgcgccggccccgccgatcccacc	Protospacer
. .* **************** *****

313. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013520 (Rhizobium sp. N113 plasmid pRspN113c, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acccgcgccggccccgccgatcccacc	Protospacer
. .* **************** *****

314. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP013493 (Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acccgcgccggccccgccgatcccacc	Protospacer
. .* **************** *****

315. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ggacccgccggccccgccgacgcccga	Protospacer
** *****************.***   

316. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_KY349138 (Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ggtcccgccggccccgccgccggcgcg	Protospacer
******************* .* *.* 

317. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NC_012529 (Deinococcus deserti VCD115 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
gtccccgccgtcccggccgatgccact	Protospacer
* .******* *** ***********.

318. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP014276 (Martelella sp. AD-3 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
cgcgccgccggccccgccgacgccgcc	Protospacer
 *. ****************.***.**

319. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NC_008759 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ggtccagccggccgcgccgatgcgcgc	Protospacer
***** ******* *********   *

320. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
gaggctgccgggcccgccgatgccacc	Protospacer
*.  *.***** ***************

321. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to MT658802 (Mycobacterium phage Aziz, complete genome) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acttccgccagccccaccgatgccacc	Protospacer
. *.*****.*****.***********

322. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to MF319184 (Mycobacterium phage GenevaB15, complete genome) position: , mismatch: 5, identity: 0.815

ggtcccgccggccccgccgatgccacc	CRISPR spacer
acttccgccagccccaccgatgccacc	Protospacer
. *.*****.*****.***********

323. spacer 12.25|3551906|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP014942 (Rhodococcus sp. BH4 plasmid, complete sequence) position: , mismatch: 5, identity: 0.815

gtagttgccggaccctgagatggcgtc	CRISPR spacer
cgagttgccggaccctgagagcgcgcc	Protospacer
  ******************  ***.*

324. spacer 11.1|3373828|26|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021405 (Celeribacter manganoxidans strain DY25 plasmid pDY25-A, complete sequence) position: , mismatch: 6, identity: 0.769

ttgccgtatcgagcgtgcggtggtgc	CRISPR spacer
acgccgtgtcgagcgtgcggtgggaa	Protospacer
 .*****.*************** . 

325. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

ttggccgccttgacctccggggccggcatt	CRISPR spacer
tcggccgcctcgacctccggggcctgctcc	Protospacer
*.********.************* ** ..

326. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

ttggccgccttgacctccggggccggcatt	CRISPR spacer
tcggccgcctcgacctccggggcctgctcc	Protospacer
*.********.************* ** ..

327. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

ttggccgccttgacctccggggccggcatt	CRISPR spacer
tcggccgcctcgacctccggggcctgctcc	Protospacer
*.********.************* ** ..

328. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019461 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.8

ttggccgccttgacctccggggccggcatt	CRISPR spacer
tcggccgcctcgacctccggggcctgctcc	Protospacer
*.********.************* ** ..

329. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019462 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed5, complete sequence) position: , mismatch: 6, identity: 0.8

ttggccgccttgacctccggggccggcatt	CRISPR spacer
tcggccgcctcgacctccggggcctgctcc	Protospacer
*.********.************* ** ..

330. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019463 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed6, complete sequence) position: , mismatch: 6, identity: 0.8

ttggccgccttgacctccggggccggcatt	CRISPR spacer
tcggccgcctcgacctccggggcctgctcc	Protospacer
*.********.************* ** ..

331. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP019464 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed7, complete sequence) position: , mismatch: 6, identity: 0.8

ttggccgccttgacctccggggccggcatt	CRISPR spacer
tcggccgcctcgacctccggggcctgctcc	Protospacer
*.********.************* ** ..

332. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
taccacgccgagcgcgccttcgccgcc	Protospacer
 ..  ******** *************

333. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctcctcgcccagcccgccttcgccgcc	Protospacer
  . .**** *****************

334. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045122 (Rubrobacter sp. SCSIO 52915 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
gtctctgccgagcccgccttcgccggt	Protospacer
* . *.******************* .

335. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP020948 (Rhizobium sp. CIAT894 plasmid pRheCIAT894a, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

336. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP018233 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

337. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to CP054924 (Verrucosispora sp. NA02020 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ccagccgccgaggccgccctcgccgca	Protospacer
   ********* *****.******* 

338. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ttcgaggccgagctcgccttcgccgcc	Protospacer
  .*  *******.*************

339. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to LN907801 (unidentified phage genome assembly 2P1, chromosome : 2P1) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

340. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KM389262 (UNVERIFIED: Pseudomonas phage F_ET2439sp/Pa1651 clone ctg7180000000624 genomic sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

341. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KM389278 (UNVERIFIED: Pseudomonas phage Phi05_1400 B clone contig00006 genomic sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

342. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to MH643778 (Pseudomonas phage YMC12/01/R24, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

343. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KT968832 (Pseudomonas phage YMC11/11/R1836, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

344. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to JF412297 (EBPR siphovirus 2, partial sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctagccgccgcgccggccttcgccgct	Protospacer
   ******* *** ***********.

345. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_041851 (Pseudomonas phage F_HA0480sp/Pa1651, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

346. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KJ477077 (Pseudomonas phage JD024, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

347. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to LT608331 (Pseudomonas phage vB_PaeS_PcyII-40_PfII40a isolate PfII40A_reads genome assembly, chromosome: PFII40A) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgtcccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

348. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to JX434030 (Pseudomonas phage JBD5, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

349. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_030918 (Pseudomonas phage JBD93, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgtcccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

350. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to MH719192 (Pseudomonas phage Ps56, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

351. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to EU272037 (Pseudomonas phage MP38, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

352. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KM389459 (UNVERIFIED: Pseudomonas phage F_ET309sp/Pa1651 clone contig00001 genomic sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgtcccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

353. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_023700 (Pseudomonas phage PA1/KOR/2010, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

354. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_024782 (Pseudomonas phage MP48, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

355. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to EU272036 (Pseudomonas phage MP29, complete genome) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

356. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctccccgccgagcaggccttcgccgcc	Protospacer
  . *********  ************

357. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP009293 (Novosphingobium pentaromativorans US6-1 plasmid pLA4, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cttcttgccgagcgcgccttcgccgcc	Protospacer
  * ..******* *************

358. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_LR134448 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 6, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctcgccgccgaaaccgccttcgccgcg	Protospacer
  .********. ************* 

359. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_018746 (Pseudomonas putida ND6 plasmid pND6-2, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cctgccgccgagcccgccttcttcgaa	Protospacer
  ******************* .**  

360. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP024895 (Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
tcgaccgtcgagcccgccgtcgccgcc	Protospacer
   .***.********** ********

361. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP025506 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

362. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_011371 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG204, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

363. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_012852 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132504, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

364. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

365. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ctcgccgccgagccggccttcgacgcg	Protospacer
  .*********** ******* *** 

366. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022668 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

367. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
acccccggcgtgcccgccttcgccgcc	Protospacer
. . *** ** ****************

368. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

369. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to MN961671 (Pseudomonas aeruginosa strain 201330 plasmid p201330-IMP, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cctgccgccgagcccgccttcttcgaa	Protospacer
  ******************* .**  

370. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to MN961672 (Pseudomonas aeruginosa strain PA15W plasmid pPA15W-NR, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cctgccgccgagcccgccttcttcgaa	Protospacer
  ******************* .**  

371. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP050088 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ggaaaggccgagcccgccttcgccgag	Protospacer
** .  *******************  

372. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KM389460 (UNVERIFIED: Pseudomonas phage F_MX560sp/Pa1651 clone contig00001 genomic sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

373. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KM389461 (UNVERIFIED: Pseudomonas phage F_TK432sp/Pa1651 clone ctg7180000000005 genomic sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgtcccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

374. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KM389462 (UNVERIFIED: Pseudomonas phage JBD23 clone contig00001 genomic sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

375. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to KM389464 (UNVERIFIED: Pseudomonas phage JBDs5 clone contig00001 genomic sequence) position: , mismatch: 6, identity: 0.778

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgttccgtcgagcccgccttcgccctt	Protospacer
 ** ***.**************** ..

376. spacer 12.17|3551534|30|NZ_CP009483|CRISPRCasFinder matches to MT952845 (Microbacterium phage GardenState, complete genome) position: , mismatch: 6, identity: 0.8

gggcccgcccgcgaagcccgtttcctggta	CRISPR spacer
gacgccgcccgcgaagccgatttcctggca	Protospacer
*.  ************** .********.*

377. spacer 12.17|3551534|30|NZ_CP009483|CRISPRCasFinder matches to MK880124 (Microbacterium phage IAmGroot, complete genome) position: , mismatch: 6, identity: 0.8

gggcccgcccgcgaagcccgtttcctggta	CRISPR spacer
gacgccgcccgcgaagccgatttcctggca	Protospacer
*.  ************** .********.*

378. spacer 12.17|3551534|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 6, identity: 0.8

gggcccgcccgcgaagcccgtttcctggta	CRISPR spacer
gggcgaaggcgcgaagccggtttcctggta	Protospacer
****  .  ********* ***********

379. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

380. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

381. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

382. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
cggcccgccggccccgccgttgccgag	Protospacer
 * **************** ****.  

383. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

384. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

385. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

386. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
cggcccgccggccccgccgttgccgag	Protospacer
 * **************** ****.  

387. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

388. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

389. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

390. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

391. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

392. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

393. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

394. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

395. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

396. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

397. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

398. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

399. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP021373 (Rhizobium sp. ACO-34A plasmid pRACO34Ac, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
gattgcgccggccccgccgatgccgtg	Protospacer
*.*. *******************.. 

400. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

401. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

402. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

403. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

404. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

405. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
accaccgccgggcccgccgatgccagc	Protospacer
. . ******* ************* *

406. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NC_011893 (Methylobacterium nodulans ORS 2060 plasmid pMNOD03, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctgtccgccggccccaccgacgccacc	Protospacer
   .***********.****.******

407. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

408. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

409. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

410. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NC_019957 (Mycobacterium sp. JS623 plasmid pMYCSM01, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ttgtccgccggccccgccgctgccgcc	Protospacer
   .*************** ****.**

411. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

412. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

413. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

414. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

415. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

416. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

417. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

418. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

419. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

420. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

421. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

422. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

423. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

424. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

425. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

426. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

427. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
cggcccgccggccccgccgttgcccag	Protospacer
 * **************** ****   

428. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP025513 (Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
accgccgccggcgccgccgctgccacc	Protospacer
. . ******** ****** *******

429. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

430. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

431. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

432. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

433. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

434. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

435. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

436. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

437. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

438. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

439. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

440. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

441. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

442. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

443. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

444. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

445. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

446. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

447. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

448. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

449. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ctcgcctccggccccgacgatgccacc	Protospacer
  . ** ********* **********

450. spacer 16.3|4864491|34|NZ_CP009483|PILER-CR matches to NC_042345 (Phage Salvo, complete genome) position: , mismatch: 6, identity: 0.824

-ctgcagtcggcggcgggaacgaggtcggcgcgag	CRISPR spacer
tctgc-gtcggcgtcgggaacgaagtcggcgtgcc	Protospacer
 **** ******* *********.*******.*  

451. spacer 22.1|5907492|29|NZ_CP009483|CRISPRCasFinder matches to MN693744 (Marine virus AFVG_250M180, complete genome) position: , mismatch: 6, identity: 0.793

ctgcttcgcagtgcatcgtcgccggcgcg-	CRISPR spacer
atgcttcgcagtccatcgtcg-cgtcccac	Protospacer
 *********** ******** ** * *. 

452. spacer 22.1|5907492|29|NZ_CP009483|CRISPRCasFinder matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 6, identity: 0.793

ctgcttcgcagtgcatcgtcgccggcgcg	CRISPR spacer
ccgagacgcacggcatcgtcgccggcgcg	Protospacer
*.*   ****  *****************

453. spacer 9.2|2785096|32|NZ_CP009483|CRISPRCasFinder matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 7, identity: 0.781

agccggtggcggcacgttgaccacgggcagca	CRISPR spacer
ctcgcggggcggcacgttgacctcggccagca	Protospacer
  *  * *************** *** *****

454. spacer 9.2|2785096|32|NZ_CP009483|CRISPRCasFinder matches to NC_014149 (Planctopirus limnophila DSM 3776 plasmid pPLIM01, complete sequence) position: , mismatch: 7, identity: 0.781

agccggtggcggcacgttgaccacgggcagca	CRISPR spacer
agttggcgtcggcacgttgaccacgggcactc	Protospacer
**..**.* ******************** . 

455. spacer 9.2|2785096|32|NZ_CP009483|CRISPRCasFinder matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 7, identity: 0.781

agccggt-ggcggcacgttgaccacgggcagca	CRISPR spacer
-gtaggtgggcggcacgttgacgacggtcaggc	Protospacer
 *. *** ************** **** ***  

456. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 7, identity: 0.741

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
atccaggccgaggccgccttcgccgcc	Protospacer
. .   ****** **************

457. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP035002 (Rhizobium acidisoli strain FH23 plasmid pRapFH23d, complete sequence) position: , mismatch: 7, identity: 0.741

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgaaaggccgagcccgccttcgccgag	Protospacer
 * .  *******************  

458. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP007050 (Rhizobium leguminosarum bv. trifolii WSM1689 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.741

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
cgaaaggccgagcccgccttcgccgag	Protospacer
 * .  *******************  

459. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.741

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
accaatgtcgagcccgccttcgccgcc	Protospacer
. .. .*.*******************

460. spacer 12.4|3550862|27|NZ_CP009483|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 7, identity: 0.741

ggtgccgccgagcccgccttcgccgcc	CRISPR spacer
ttcttcgccgagcccgccctcgccgcg	Protospacer
  . .*************.******* 

461. spacer 12.5|3550913|27|NZ_CP009483|CRISPRCasFinder matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 7, identity: 0.741

ggcgctacccgcgccggttccgggttg	CRISPR spacer
acggctacccgtgccggttccgggggc	Protospacer
.  ********.************   

462. spacer 12.17|3551534|30|NZ_CP009483|CRISPRCasFinder matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gggcccgcccgcgaagcccgtttcctggta	CRISPR spacer
gaccgtgcccgcgaagcccgtgacctggtc	Protospacer
*. * .***************  ****** 

463. spacer 12.23|3551810|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 7, identity: 0.741

ggtcccgccggccccgccgatgccacc	CRISPR spacer
ggtcccgccggccccgccggccatggc	Protospacer
*******************..  .. *

464. spacer 12.25|3551906|27|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032828 (Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.741

gtagttgccggaccctgagatggcgtc	CRISPR spacer
acttttgccggaccctgcgatggcgcg	Protospacer
..  ************* *******. 

465. spacer 22.1|5907492|29|NZ_CP009483|CRISPRCasFinder matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.759

ctgcttcgcagtgcatcgtcgccggcgcg	CRISPR spacer
cgcgcaggcggtgcatcgtcgccggcgcg	Protospacer
*   .  **.*******************

466. spacer 22.1|5907492|29|NZ_CP009483|CRISPRCasFinder matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 7, identity: 0.759

ctgcttcgcagtgcatcgtcgccggcgcg	CRISPR spacer
cgcgcaggcggtgcatcgtcgccggcgcg	Protospacer
*   .  **.*******************

467. spacer 22.1|5907492|29|NZ_CP009483|CRISPRCasFinder matches to NC_013193 (Candidatus Accumulibacter phosphatis clade IIA str. UW-1 plasmid pAph01, complete sequence) position: , mismatch: 7, identity: 0.759

ctgcttcgcagtgcatcgtcgccggcgcg	CRISPR spacer
gggtgacgcagtgcatcagcgccggcgcg	Protospacer
  *.  ***********. **********

468. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
cggcgccaaccgccgaagtggtggccctggcg	Protospacer
 .*.*.*. **.**** ***************

469. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 8, identity: 0.75

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
cggcgccaaccgccgaagtggtggccctggcg	Protospacer
 .*.*.*. **.**** ***************

470. spacer 9.2|2785096|32|NZ_CP009483|CRISPRCasFinder matches to FJ937737 (Burkholderia cenocepacia phage BcepIL02, complete genome) position: , mismatch: 8, identity: 0.75

agccggtggcggcacgttgaccacgggcagca	CRISPR spacer
ggcggccggcggcacgttgacgtcgggcaggt	Protospacer
.** * .**************  *******  

471. spacer 9.2|2785096|32|NZ_CP009483|CRISPRCasFinder matches to NC_012743 (Burkholderia phage BcepIL02, complete genome) position: , mismatch: 8, identity: 0.75

agccggtggcggcacgttgaccacgggcagca	CRISPR spacer
ggcggccggcggcacgttgacgtcgggcaggt	Protospacer
.** * .**************  *******  

472. spacer 12.17|3551534|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP020333 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM170, complete sequence) position: , mismatch: 8, identity: 0.733

gggcccgcccgcgaagcccgtttcctggta	CRISPR spacer
gccgccgcgcgcgaagccggtttcctgaac	Protospacer
*   **** ********* ********.  

473. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP045296 (Paenibacillus cellulositrophicus strain KACC 16577 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
ttctgtcgccgaccgatgcggtggccgtcggt	Protospacer
   ******* *******.******* * *  

474. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 9, identity: 0.719

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
gctgctatcccaccgatctggtggacctggct	Protospacer
*    *  ********* ****** ****** 

475. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 9, identity: 0.719

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
gctgctatcccaccgatctggtggacctggct	Protospacer
*    *  ********* ****** ****** 

476. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP047899 (Pseudarthrobacter sp. YJ56 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

ttggccgccttgacctccggggccggcatt	CRISPR spacer
cgtgccgccttgatctccggggcgggggga	Protospacer
.  **********.********* ** .  

477. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 9, identity: 0.7

ttggccgccttgacctccggggccggcatt	CRISPR spacer
accagcgccttgacctccgccgccggcagc	Protospacer
 . . **************  ******* .

478. spacer 12.3|3550808|30|NZ_CP009483|CRISPRCasFinder matches to NZ_CP015735 (Arthrobacter sp. U41 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.7

ttggccgccttgacctccggggccggcatt	CRISPR spacer
cgtgccgccttgatctccggggcgggggga	Protospacer
.  **********.********* ** .  

479. spacer 5.3|1062109|37|NZ_CP009483|CRISPRCasFinder matches to KJ025957 (Serratia phage PS2, complete genome) position: , mismatch: 10, identity: 0.73

ggtgttgccgatatttccaccacccagattggtgcta	CRISPR spacer
aatgttgccgatatttccatcacctagaacaatgaca	Protospacer
..*****************.****.*** ...** .*

480. spacer 5.5|1062214|37|NZ_CP009483|CRISPRCasFinder matches to NZ_CP014361 (Methylomonas sp. DH-1 plasmid, complete sequence) position: , mismatch: 10, identity: 0.73

gccgctgcccaggttgatgtcgccccggtttccgcca	CRISPR spacer
atcctggatcaggttgatgtcgcccaggttgccgccg	Protospacer
..* . * .**************** **** *****.

481. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 10, identity: 0.688

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
atccacagcccaccgatgtggtcgcgctggtg	Protospacer
.  ... *************** ** ****.*

482. spacer 9.2|2785096|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP027239 (Dietzia sp. oral taxon 368 strain W5195 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

agccggtggcggcacgttgaccacgggcagca	CRISPR spacer
cacctgaggcggcacgttgaccacgatcgagc	Protospacer
 .** * ******************. *..  

483. spacer 16.3|4864491|34|NZ_CP009483|PILER-CR matches to NZ_CP019438 (Thioclava nitratireducens strain 25B10_4 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ctgcagtcggcggcgggaacgaggtcggcgcgag	CRISPR spacer
aagccgtccgcggcgggaacgaggtcgaacccga	Protospacer
  ** *** ******************.  * ..

484. spacer 16.3|4864491|34|NZ_CP009483|PILER-CR matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.706

ctgcagtcggcggcgggaacgaggtcggcgcgag	CRISPR spacer
ccccgtccggcggtgggaacgaggtcggtgccga	Protospacer
*. *. .******.**************.** ..

485. spacer 16.3|4864491|34|NZ_CP009483|PILER-CR matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 10, identity: 0.706

ctgcagtcggcggcgggaacgaggtcggcgcgag	CRISPR spacer
ccccgtccggcggtgggaacgaggtcggtgccga	Protospacer
*. *. .******.**************.** ..

486. spacer 16.3|4864491|34|NZ_CP009483|PILER-CR matches to NC_047910 (Faecalibacterium phage FP_Epona, complete genome) position: , mismatch: 10, identity: 0.706

ctgcagtcggcggcgggaacgaggtcggcgcgag	CRISPR spacer
gggttgtaggcggcgggaatgaggtcggccagtc	Protospacer
  *. ** ***********.*********  *  

487. spacer 5.5|1062214|37|NZ_CP009483|CRISPRCasFinder matches to NZ_CP014361 (Methylomonas sp. DH-1 plasmid, complete sequence) position: , mismatch: 11, identity: 0.703

gccgctgcccaggttgatgtcgccccggtttccgcca	CRISPR spacer
atcctggatcaggttgatgtcgcccaggttgccgctg	Protospacer
..* . * .**************** **** ****..

488. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 11, identity: 0.656

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
atccccagcccaccgacgtggtggcgctggtc	Protospacer
.  . . *********.******** ****. 

489. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 11, identity: 0.656

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
atcctcagcccaccgacgtggtggcgctggtc	Protospacer
.  . . *********.******** ****. 

490. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 11, identity: 0.656

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
acccccagcccaccgacgtggtggcgctggtc	Protospacer
.  . . *********.******** ****. 

491. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 11, identity: 0.656

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
acccccagcccaccgacgtggtggcgctggtc	Protospacer
.  . . *********.******** ****. 

492. spacer 7.1|1937389|32|NZ_CP009483|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 11, identity: 0.656

gagtgtcgcccaccgatgtggtggccctggcg	CRISPR spacer
acccccagcccaccgacgtggtggcgctggtc	Protospacer
.  . . *********.******** ****. 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	515358 : 592647	52	Gordonia_phage(22.22%)	tRNA,integrase,transposase	attL 591306:591365|attR 594672:594762
DBSCAN-SWA_2	2361670 : 2392391	24	Bacillus_phage(33.33%)	tRNA,integrase,transposase	attL 2381028:2381087|attR 2392656:2392979

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP009483|515358:592647|DBSCAN-SWA
ACTAACCGTCACGCCCGGGGCGCTTGCGACCAAGCGGCGCGGGAGCGACGGCTCCGGGCGCCAGCCGGCGTGCGGTCACCAGGAATGCGGTGTGGCCGCGCATCGCATGCTGCGGCCGCACGGCCAGCCCGACGACATTCCAGCCGCGCTGCAACGTCTCCCACGATCGTGGCTCGGTCCAACGTTGTTGGGCCCGCAGCGCCTCCACGACCGTCGAAAGTTGGGTGACGGTGGCGACGTAGATCACCAGCACCCCGCCCGCCGACACCAGCCGCGACACCGAGTCCAGAACTTCCCAGGGAGCCAGCATGTCCAGCACGGCCCGGTCGACCGAGCCGTCGGGCAGGTCGGAGTCGGCGACGTCGCCCACGATCAGCCGCCAGTTCTGCGGAGCCGCACCATAGAAGTTCGTCACGTTGCGACAGGCATGCTCGGCATGGTCGGCGCGCTGCTCGTAGGAGATCACCCGGCCCTCGGGCCCGACCGCCCGCAACAGCGACAGGGTCAGCGCGCCGGACCCGGCTCCGGCTTCAAGCACCCGGGCGCCCGGAAAGATGTCGCCCTCATGCACGATCTGAGCGGCATCTTTCGGGTAGATCACCTGTGGCCCACGCGGCATTGACATCACGTAGTCGACCAGCAACGGGCGCAGCACCAGAAACGGCGCACCGTTACTGGATTTGACCACGCTGCCCTGCTGGAGCCCGATCACCGCATCGTGGGCGATCGAACCTCGGTGGGTGTGGAACTCGTTGCCCGGGGTGAGCACCATCGTGTAGTGGCGGCCCTTCGCGTCGGTCAGCTGCACGCGTTCGCCAGCGGCGAAGGGACCGGTTGCTGACACGCCGTCTAGCGTGCCAGCCGGCTCACCGGAGCAGGTCTTCGGGGTTGTCGGTGTCCGGCCCTAGGCTGCGAGCATGGCCGACCAGCTGATACCCGAAGCGGACCTGCGCATCCGGCCGGCGCTGTCACCGTCGCGGGCGACCGATTTCAAGCAGTGCCCGCTGCTGTACCGGTTCCGGGCGATCGACCGGTTGCCCGAGGCACCGTCGGCGCCGCAGTTGCGCGGATCGGTGGTGCACGCCGCACTCGAGCAGCTCTATGCCCTGCCCGCGGTGCAGCGCGGCCCGGAGACCGCGCGGTCGCTCGTGGAGGCCGCCTGGGAGCAGGTGATCGCCGGTGAGCCCGCGCTGGCCGATGAACTGCAGCCACAAGCACTGCTCGACGAGGCGCGCGCCTTGCTGTCGGGGTATTACCGGCTGGAAGACCCGACGCGGTTCGACCCGCAGTGCTGCGAGCACCGTGTGGAGGTGGAGCTGGCCGACGGCACGCTGTTGCGCGGCTACATCGACCGGATCGACGTCGCCGCGACCGGCGAGTTGCGGGTGGTCGACTACAAGACGGGTAAGGCGCCGCCGGCCGCGCGGGCGCTGGCCGAGTTCAAAGCCTTGTTCCAAATGAAGTTCTACGGGGTGGCGCTGTTTCGGTCGCGTGGCGTGCTGCCCACCCGGTTGCGACTCATCTACCTGGCCGACAGCCAGGTGCTGGATTACTCGCCGGACCGTGACGAACTGCTGCGTTTCGAGAAGACGTTGATGGCGATCTGGCGTGCGATCCAATCCGCGGGCAGGTCAGGAGATTTCCGTCCGAATCCGTCGCGGCTGTGCGATTGGTGCCCGCACCAGGCGCATTGCCCGGCCTTCGGCGGGACGCCGCCGCCATACCCCGGGTGGCCCAATTACGCCGGCGCCGACACCGTTGTGCGCCCGACCGAACCGGCGGCATGAACGGTTGCTTCTACCGTCGGCTCGGCGACGACGGTGACTATCAGGTCTTTGACTCCACCGATTACACGCGAAGCAACTGGAATCCCGAAATCCAGCATGGCTCACCGCCGTTAGCCCTGCTGACCAAGCTTATCGAAGAGCTGTCGGCGGGCTCGAGCCTGCGGATCGGCAGGCTCAACCTCGACATCCTCGGGGCGATCCCGGTGGCCCCGGTGCGAGCCAGGGCCTGGGTGGAACGCCCGGGGTCGCGGGTCTGCTTGATGGTCGCCGAACTGCACGCCGATCGCGAGGGCGGACCCGCGCGGGCGGTGGCCCGGGTGACGGCATGGCTGTTGGCGGTCGGTGACACCGCAGACGTCGAATCAGCGCGGTACCCGGCGGTGGTGGAAGGACCCGCCGAGCCCCTTCCGGCCGTCTTCGCCGACGCCGGCGGCTACTTCGATGCGATTAGCTGGCGCCCACAACAGTCCGCCGGCCATTCGGGCGCCGTGTCCTGGTTCACCCCGATCGCACACATCGTCGACACCGACCCCACCACGGCGCTGCAACGGCTTGCGGTCGTCGTGGACTGCGCCAACGGTGTCGGTGCGGTCCTGGATCCGAATCAGTTCGTGTTCATGAACACCGACACCGTGGTGCACCTGCATCGGCTTCCGACCGGCGACGATTTCGCGCTGCGGGCTCGGGCATCGGTCGGGCCGGACGGCGTGGGAGTCACCACCGCGGAGGTCTACGACAAGGCCGGTTTCATCGGCACCTCGGCCCAGACACTCCTCGTCCAACGCCGGGCGCGCAGCTAGTTCGATCGTGGCGACCCGCCGCGCCCGGCTACGCCGGGCTTGCGATCGCCACTAGTCCGATGGTGGCGACCCGCCGCGCCCGGCTAGGCCGGGCTTGCGATCGCCACTAGTCCGATGGTGCTGATTCAGTCACCGCGCTCAGCCGAGTCCTGGGCCCGGCAATCACATCTGTCACATAGGCCGCTGGCTGCCCGATGCGCAATTTGCCCGCCACGTGTCGACAACACGTCGTGGCCTGCCGCGCTGGCGTCAAAGTCGCTGAAAGACGGACACAACCAACAGCTCACACCCGAGCATCCCTGATGTGGCTGATGGAAAGCCGCAGCTACGTCCTACAATTCGGGTTACCAGATCAGCGCCGTCCTAGTCCAGTGGCTCCATCTCCTGCAGCATCGTGGGAACGAGCTCGCTGACCGTGGGGTGGATGTGCATGGTGCGCGACAGCGTGGTGTAGGGCGCTCTTGCCGACATGACATCCAAAATGGCGTGGATGACCTCGTCTCCCCCGACGCCGAGGATGGCCGCACCGAGGATCTCGTGAGTGTCCGCGTCGACCACGATCTTCATAAACCCTTGCGTCTCACCCTTTTCCACGGCTCTGCCGACTTTGGTCATCGGTCGCTTGCCGACCAGCGCCTTGCGACCTGACGCACGAACCTGAGCGACGGTCATCCCGGCGCGCCCCAGCGGCGGGTCGATATAGAGGGCGTAGGTGAGAATGCGGTCGCTCACCCGACGCGGATCCCCGTCGAGCAAGTTGGCGGCGACGATCTCGTAGTCGTTGAACGACGTATGGGTGAAGGCGCCCTTGCCGTTACAGTCGCCCAGCGCCCAGATGTGGTCGACGGTGGTCTTGAGCTGGTCATCGACCACGACGTAGCCGCGGGCGTCGGTCTGCACACCGGCCGCCTCCAGACCCAAGTCGTCGGTGTTGGGTCGGCGTCCCACCGCCAGCAGCAGATGGCTGCCCGCAATGGCGGGCGCACCGACGCTGGGAGTCAGCTCGAAGCCCCCGAAACCATTGTCCCGCTTGGCAAGTCGCACATCGTCGGCATTGACGACGACATCGATCCCTTCGGCTTCGAGGATCTCCCTGATACTCGCCGAGACATCCTCGTCCTCGCGGGACGCCAGCCGTGGGCCGCGCTCCACGACGGTGACCTGGGCTCCGAAGCGGCGATACATCTGGGCGAACTCCAGCGCGATGTAGCTGCCGCCGACGATCACGAGATGCTGCGGCAGCGTGTCGAGTTCGAGGATGGAGACGTTGGTGAGGTAATCGACGTCGGAAAGCCCGGGAATGTTGGGCGCGACGGCGCGGCCCCCGACGTTGAGGAAGATCTGGTCGGCTTGCAGCAGCTGATCGCCGACTCGCAGCGTGTGTGGATCCTCGAATCGGGCGTGGCCGCGCACCACGGTGCAGCCATCCATGCCTTCCAGCCAGTCCTCGACGGCCTTGCGATCATTGAGCATGACGCCGTCTTTGCGGGCCTTCACTTTCGCCATGTCCACGCTGACCGATCCGGTGCCGACGCCGTATTCGGCAGCGCGGCGGGCCACATGGGCCGCGTGGGCGCTGGCCACCAGCGTCTTGGTCGGAATGCAGCCGTTGTTGACGCAGGTACCGCCGATCAGCTTGCGCTCCACAACGGCGACCCGCTGACCAGCGCCGGTCAGGCGGCTCGCCAGCGAAGGCCCGGCCTGGCCGGCGCCGACGATGATCGAGTCGAACCGCTGTGTCATAGTGCAGCCGCCGATGCGACGACGGCGAATCCGCCTAACACGGCGACGGAATCCTCGAGCAGTGCGATCGGCAGGTCGCGGCCGCCGCTGGCGGCCACCAGCCGGCGACGCGCGTGATAGCCGCCCAAGGTGCCCAATACCGCTCCGACAACCCCGGCACCGAGCCCGCCGAACTTGTAGCCCCAGGCGGTGCCGATCACCGCGCCGGCGAACCCGCCCAAGATGATCCGGACCGCGAACACCGGCGCGGCGGTGCGCGGCGGCGTCTTGGGAAGCTTGTCGTTGACCAGTTCGGCGACCGCAAGGGCGCTCAGGGTCACCACCGTCACGATGTTGCCCACCCAGGATGCCCAGGTGTGCTGCAACGTTGGGAACCAGCCGAGGTAGCCGGCCCAGGAGACTGCCGCGGGAGCGGTCACCGATCGCAACCCGGCGACCACGCCGATCAACAAAGCTAGGACGAGGACAAGTACGTGCGTCACAGCGATCCCTTCCGGGGACAGAAGAACAGCCTGGCGACGATACGGAGACGGCCCATGGATGACCACCGGCAATCAGCCCACCGCGGACGCTAACACAGCGGCCGCCCGCCCGGGCATTACCGCGGTCAGAATCGGCAGAACCTGATATCCGACGCCAGAATCGCTTTGGCCCCGATGGCGGCAAGCTGGTCCATGACGCCGTTGACGCCGCGGCGCGGGACCAGCGCACGGACTGCGACCCATTCCGGGTCGGCCAGCGGGGCGATCGTCGGCGACTCCAATCCGGGCGTGATTGTGGTGGCCTGGTGCAGCACTGCGCGCGGACAGTCGTAGTCCAACATCAGATACTGCTGGCCGAACACCACACCTTGTACCCGGGCGACCAACTGGTCGCGCGCCTCGCTGTGCTCCGCGCCGTCGCGGTCGGCGCCTTCGATGAGCACCGCCTCCGAATCACACAGCGGCTCGCCGAATGCCACCAGGTTGTGCAGGCTCAGGGTGCGACCGGAGCCCACCACGTCGGCGATGGCGTCGGCCACGCCGAGTTGCACCGAAATCTCCACAGCGCCGTCGAGCCGGATCACGGTTGCCTCGATGCCCTTGGCGGCCAAGTCTTTTCGGACGAGGTTCGGATAGGCGGTGGCGATCCGCTTTCCGGCCAGGTCGGCCGTCGTCCAATCCCGCCCGGCGGGACCGGCGTACCGGAAGCTCGACGACCCGAAGCCCAGAGCCAAACGTTCCCGTACCGGGGCGTCGGAATCGCAGACCAGGTCGCGCCCGGTGATCCCGAAGTCGAGTTGCCCCGAACCCACGTAGATGGCTATGTCTTTGGGCCGCAGGAAGAAGAACTCGACGTTGTTGGCCGGGTCGATGACGGTCAGGTCTTTGGGGTCGGTGCGGCGCCGGTAGCCGGCCTCGGCCAGGATTTCGGTGGCCGGTTCGCTCAACGCACCCTTGTTGGGAACGGCCACGCGCAACATGCTCACAGCTTCCGGTAGACGTCGTCGAGCGACAGTCCGCGGGAGATCATCAGCACCTGCGTCCAGTACAGCAATTGGCTGATCTCCTCGGCCAGGGCGTCGTTGGCTTCGTGCTCGGCGGCCAGCCACACCTCGCCGGCCTCCTCCAGGATCTTCTTGCCCAGCCAATGCACCCCGGCGTCCAGCGCAGCTACGGTAGCGCTGCCGGCGGGCCGGGTGCGGGCACGATCGCCGAGTTCGGCGAACAGATCCTCGAAGGTCTTCACGGCCAGCGATTGTTTCATGCGCCGGCGAGCGACGTCACGGCGGTTTCGTTGGCTCTTGTTCTGCGGTGGTCGAGGGCCTGCCGCGCCGGCGTTGTCCTAGCAGCAATGGTCTTGGCACTATCTTCACGTTCTGGCCTGACCGCAGGATTTCGTTTGACGACTGTCGTTACCGCGGAGCAGGGTCCGATAGTGCGCCGAGATATTCAGTGGACAACGTCCGGGCTGCGGTTGCGCCGACGGGCCAGTCGCGCGGGGGATTTGAACTGGCTGTTTCTTCCCGGTGGACCGGGAATCGGTTCGGAGAGCCTGCATGAACTGGTCGACACCGTCGATGTACCCGGCTGCTCGTGGATGGTCGACCTGCCTGGCGATGGCTCCAACGTCAACGCTCCGGGAGCACCCGCCGATCCCTACGACCTATGGCCGCAAGTTCTGCTTGAAGCCGCCCACGCCGTTGCACATCCTGTTTTCGTGGGGCACTCCACCGGGGGCGAATACCTGCTGTCCGTTCCGGCATTGGATGGATGTTTGGCAGGGCTGGCGCTCGTCAGCACCGCCCCTGACGCATCGTGGATACCGGTGTTCGAGCACATGACACGGAACAATCGGTTACCCGGCGTCGAATACGCCACCACCCGTTACCTGTCCGATCCCACCGACGACCACCTTCGCCGCGTTGCTGTGGAATCTGCGCCGTGGAACTTCGCCGCCCACACCGTTGCCCGCGGGACGGAGATCCTTGCGCGATTGCCCTATAACGCTCGGGCTGCGCAATGGTCGGAGGCCAATTTCGATCGCGGTTACCGATCAGCCTGGTGGCCAAGCACGCTGCCCACACTCATCGTGAGCGGCTCGGCAGACCGCATCGTGACCCAAACATTGTGGCACGACAAGCGATTCCACACGCCAAACACAACCTGGCGCGTCATCGCCGGCGCCGGCCATTTTCCCTGGATCGAACAACCAGCCGCCGTGCACGACGCCTTCGCAGCGCTCGTCGGGCAGATCGACAACCGCCGTACCACCGACTGAATGGCACCCCGACTGTGTCACAGGTGAACGCTGATGCCGGCGCAATGGTGCAACGCGATCACTATCGCGTCGATGATCGGTTGGATCCGGCGGTCGTGGCCGCGATTGGATTTCGCAAGCGCTGCAGCAGTTTGAGGCGGACACGGCGGCCCGGGCTAGATAACCCGGCGTGCCCCTGGGCCGCCGCACCCCGGACCAGTACGCTGCCCATCCAGACCCACCGACATCCACTGACCTGCGAAATCAACCAAATCCGGAACACCCACGGACTTGGCATCGCTGGAGAGGTTCAACATGGCAGCCGAAACGGCAGACGCAGCCGCACGTCCCAACATTCTGGTGATCTGGGGCGACGACGTCGGGATGTGGAACATCTCCGCCTACCACCGCGGGATGATGGGCGGCTCGACGCCCAACATCGACCGGATCGCCAACGAGGGCATGATCTTCATGGACCACTACGCGCAGGCATCCTGCACGGCGGGCCGCGCCGCCTTCATCACCGGGCAGTACCCGATCCGGGTGGGTTTATCCACGGTCGGTCTCCCGGGGTCGGATATCGGTCTGCAGAAGGAAGATCCGACACTGGCCGAGATGGTCAAACCATTGGGCTACACGACCGGACAGTTCGGCAAGAACCACCTCGGCGATCGCGACGAGCACTTGCCGACCCTGCACGGTTTCGACGAGTTCTTCGGGATCCTGTACCACCTCAACGCCGGCGAGTACGCCGAACAGTACGACTTCCCGACCAATCCGGAGATCGTGGAGAAGTTCGGCTTCGGTCAGCGCGGTGCGTTGCACTGCTGGGCCAATCCCGACGGGACCCAGCGTATCGAGGACACCGGACCGTACGGCCGTGAGCGACAACGCACCCTCGACCGTGAATTCCTCACCGAGACAAAGCGGTTCATCCGCGATGCGGCGGCTGCAGAAACGCCGTTCTTTGTGTGGCACAACTCGACTCGGATGCACTATCGCACCAACCTGGCACCGGAGTACGACGGCAAGAGCGGCTACGGCGTCTATGCCGACGGGATGATGGAACTCGACGATCACGTGGGCGAACTGCTCGATCTGCTCGACGAACTCGGCATCGCCGACAACACCCTGGTGATGTGGTCGACCGACAACGGAGCCGCCTGCAACAGCTGGCCCGACGGCGGCAACCATCCCTTCGCGCGGGAGAAGGGCGTCGGCGGCTACGAGGGCGCGTTCCGGGTGCCGGCGCTGGTGCGCTGGCCCGGCGTGATCCCGGCCGGCGTCGCCAGCGGGGAGTTCATGGCGATGGAGGACTGGATTCCCACCATCATGTCGATGCTGGGCCAGCCGGATCTCGCGGACTCGCTCAAGAAGGGCGCCACCATCGGTGGGCGGGAGTACCGCGTACACCTTGACGGGGTCGACCAGACCGACCTGCTCACCGGCCGCGGCAAATCCAAGCGCATGGAGTTCTACTACTTCACCGAGACATCGCTGCACGGATTGCGTTACGGCGACTGGAAAGTGCTGTTGAAGACCCAGGACCGGTGGTTTAACGGCATCCAGCAGAAGCTGACCACCCCACTGATCACCAACCTCAAGCTCGACCCGTTCGAACGTTTCCACAAAGCGCGGGGATTCGACGAATGGCAGGAGAATCACGCTTGGCTCTACGGCCCCGCCGCCCTGCAAGTGATGCGGTTCCTGGCGACGTTGCACGAATTCCCGCCGCGGATGCGCAGTTTCGGCATCGACGTCGACGAGTTGTTGAACCAACTCAACCCGGCTCGACACCGATAGCCGAAGCGAGGACAAAGTCATGGCAATCACCGAATATCGGCCCGGTACAACGTTTCCCGGTGTGATCGGCCGCACCGCCGACGAGTCGACGCCGGCCTGGCCCGCCCTGAAGCGGCCTGCCGAGGGCGCACCGAATGTGGTGTTCATCGTGCTCGACGACACCGGATACGGGCACCTGGGCTGCTTCGGCAGCCCGATCTCGACACCGAACATCGACGCGTTGGCCGCCGACGGCCTGCGGTATTCCAACATGCACACCACCGCCCTGTGCTCGCCGTCGCGGTCCTGCATCCTCAACGGCCGTAACCATCACTCCAACCACCTGGCGTGTCTGACCAACGGGTCGACCGGATTCCCCGGCTCCGACGGTTACATACCGTTCGAGAACGGTTTCCTGTCTGAAATTCTGCGGGCACAGGGCTACAACACCTACTGCGTCGGCAAATGGCATCTGGCGCCGGAGGAAACGATGACCGCGGCCGGGCCCTACGACCGGTGGCCGCTGGGACGCGGGTTCGAGCGCTACTACGGCTTCCTGGGCGGCGACACCCACCAGTACTACCCGGATCTGGTACGAGACAACTCCCAAACCGAACCCGAAGCCACCCCGGAGCAGGGCTATCACCTCACGCCCGATCTGGTGAACAAAGCCAAGGCAATGATTGCCGACGCCAAGCAGGTCGCCCCGGACAAGCCCTTCTTCCTCTACTTCGCCCCCGGCGCGACACACTCACCCCACCATGTGCCCAAACAGTGGGCCGACCGCTACGCCGGCAAGTTCGACGCCGGCTGGGAAGCCTACCGCCAGCGGGTGTTCACGCGACAGCGAGAACTCGGGCTCTTGCCGGCAACGGCCGAGCTGTCGGCACCCGATCCCGATGTCGCGGACTGGGAGACGCTGCCGGCCGACGAACGCCGGCTCTACGCCCGCATGATGGAGGTGTTCGCCGGCTTCCTCGAGCACACCGACCACTACATCGGCGAACTCGTGCAGTTCCTCAAAGACCTGCACGAATACGACAACACGGTGATCATGCTGGTCTCTGACAACGGGGCCAGCGCCGAGGGAGGCCCCACCGGCTCGGTCACCGAGGTCCGTTTCTTCAACAACGTCGCCGATACCGTCGAGGAGGGACTGGCCCGCATCGACGAGATCGGCGGCCCCACGGTGTTCAACCACTTCCCGTGGGGCTGGACGCACGCCGGCAACACCCCGTTTCGGCGGTGGAAGCGCGAGACCTACCGCGGCGGCTCGAGCGACCCGTTGATCGTCACCTGGCCGCGCGGTATTGCCGCGCGGGGCGAGGTGCGATCCCAATACGCCCATCTGATCGACATGGTCCCGACCGTGCTCGAGGCGCTGCGCATTGACCCACCGACATCGATCGGCGGGGTCACCCAGTCGCCGATCGAAGGGGTCAGCTTCGCGCACACCTTCGACGACGCCGCCGCCCCCACCCGGCACCTCACCCAGTACTTCGAGATGCTGGGCCACCGCTCGATCTACCACGACGGGTGGCGCGCCGTATGTCCTTGGCCGGGAACGTCGTTCGCCGAATCCACTCACAAGTTCGGCGACGTGATCACCGCGGAGATGCTCAGCCAGCTCGATGAATCCGGGTGGGAGCTCTACCACGTCGCCCAGGATCCCGCCGAGACCACCAACCTGGCCGGGCAGGAGCGTGCGCGGCTGATCGCGATGATCACACTCTGGTACAGCGAAGCGGGAAGGTACAACGTGTTACCCATCGACAGCCGCGGCCTGGCCCGCGCTTTCGTCGAGCGTCCGCAGATTGCCGGCGCGAACCGCACTCGATACGTGCTCTATCCGGGCACCCAGGCCATTCCCGCGGCCGCCGCACCGAAGATCCTCAACCGGCCATACTCGATCAACGCCGAGGTTGAGCTCACCGAGGAATCGTCGGGCGTCCTACTGTCCATGGGCGGCAATGACGGGGGAATCACCTTGTACGTCAAGGACGGTCAGCTCTGCTATGCGCACAACTACGTCGCCAAGGAGATCTTCACGATTCGCTCGGAGCAACGGGTCCCGCCGGGGCGGCACTTCCTCAGCGTGGAATTCACCCCGACAGGTCCGGTGGACCTCAAGAACGGCAGAGGCACTCCGGGCGACGTGACACTGTTCGTCGACGGCGCTGCGGTCGGCCGCGGCGAATTTCCGGTGACCACGCCGCTGCGGCTGGCCCAGGGCGGAGCCATGTTGGTCGGCGCCAACACCGGCTCCTCGGTAACCCCCGACTACGACCCGCCGTTTGCCTTCGACGGCCGAATCCACCGCGTGATCGTCGACGTCAGCGGCGAGCATGTCGAGGACTATCAGGCGCAGATGAAGATCGCGCTCACCAAGCAGTAGCTGCGTGGACAGCCGTCGTCCACCAAGGGTTCGGGTTCCTTGGCGACATAACCGTCAGAGGCGGAAAGCCCGCACGTTGGCCTGGGCAAGCGCAACTTTCAGCCGAGCACCCAACTGGTGGAGTCATCACCGCACACATGCTGCGCCCAACCGCTTGGCAACATGGGCACTTGCACACCGTCACAACACGTGTGGCCACTCAGCGTGGTCAGCCCCCCGGCCTGCGGGACGGTCCCGTTGGTGATGGTTCCGGCAAAGCCCACGGGCCCGCCCAACTCAGCGGGCGAAACCGCGCTGCCAGCAGTGGCAAGCGACCCGTCGGCACCAACAGCCATAGCGGCAAACGACGCCGGCGCCAGCTCCAGCGCCACCGTCGTGCCCTTCAACGCGCCGACGCCCAGAGCGGCACCGCCGGACAGCGCCGTCGTCGTCGCCAACTGAGTCACCAAGCCCGGACCGCCGACAAATCCCAGATTCCCCAAAAACCACGCAATCACTAATTCGCAAATATCGGCCAGACCCACGATGAAAATCCATCCGGCCTCAAGGAAGAATTGGAAAGGAATAATCGCCAAATTCACTATGAAGCCAAGAAATTGTTCGGCCATGGCGACATGTCCGGTTAATAGCGCAATCACCGCGAGCAGAACACATAACGGAATGAACAGCAATGCAAGAACAGTAGCCACTAACGATTCTCTGATGCAATGCAACACCCCCACGACGGCATCGAGCAATATTTGGAGAATCTGCCAAATGGGAAATGGTGTGATGGTTGTTTCAATGGCGTTCACGAGGCCGGCGCCAGGTTTGATGATGGCTGGCGCCGGTGGGGTGTGCGGTGTCGAAGCAACCGCCGGCGAAGAAGTCGTCTCGTAGACATTCATGATGGTGGCGGCCTGCATCCACATGCGCGCATAGTCGGCCTCATTGAACGCGATCGGTATCGCGTTGACACCAAAGAAGTTTGTCGCCAGCAACACCGCATGCGTGGCGTGGTTGGCAGCCAACTCCCCCAGCGTCGGCATTGCAGCCAACGCTGCCTGGTACGCCGCCGCCGTGATCTCATGGACAGCAGCGACCTGAGCGCAATCGGCACTTTCCTGCATCACCCATGCCAGATAGGGCACGTAGGCTGCGACACAACATTCCGCGGCAGTACCCCGCCACGCCTCGGTCCGCAACGCCGCTACCACCGGAGCCAGTTCGTCTGCCACCGCGCCGTACTCGGCGCTCAACGATGACCACGCCTGGGCCGCGGCAATCAAGGACGCGGGTCCGGGTCCGGCGCTCAGCAGCGCCGAATGCACTTCCGGCGGGAACGCCATCCATACCGGCGCGCTCACCGGCACAACTTTTTTGTGCCCGCGCTCGCTGCTGGGCGATCCCGGCCGCCGTCGCCGCCGCCAATCCACCGCGCCGAACACAACGCCACTTCAAGCCCCTCAGACACCTGCACCGCCGCTACAGCCATCGCCAAACCGGCCGCTTCGATTTCGCGCCGTAAAAATCCTGGTGAATTAAAGGAATTGTTTCGATTAACAATGACAGGCGGTATCCACCGGTATACGGAATTCGACTGTCCCCCGATCGGCGGACAGACAGCGCGTCGTCGAACTGATATCAGGTCGATCGCGACCAGCCGCCGTTACCGGTGGCCGAGTCAGACGTTGAAGTACTTGGCCTCGGGATGGTGCAGGACGAACGCGTCGGTCGACTGCTCGGGATGCAGCTGCAACTCCTCGGACAGCGTCACGCCGATACGGTCGGGCTCCAGCAGCTGCATCATCTTGGCGCGGTCCTCGAGGTCCGGACATGCCCCGTACCCGAAGGCGAACCGGGCACCCCGGTAACCCAACTTGAAATAGTCCTCGACGGCGTCGGGGTCCTCGGCGGCCATCGTGCGGTCGGCCGAGTACCTGAGCTCCTCCCGGATACGCCGGTGCCAGTACTCGGCCAGCGCTTCGGTGAGCTGCACGCCGATACCGTGGACTTCGAGATAGTCGCGGTAGGAGTCGGCGGCGAACAACTCGTTGGCGAAGTCGGCGATCGGCTGGCCCATGGTCACCAGCTGGAACGGCAGCACATCCACCTGACCCCGCTCGCGGGCGTGCTCGCGTGACCGGACGAAATCGGCGATGCACAAGAACCGGCCGCGCTGCTGGCGCGGGAACCTGAAGCGGTAGCGTTCCTCGGCGTCGGCTGCGGGTTCGGTGAGGACCACGACCTCGTCACCTTCGGACACAGCCGGGAAGTAGCCGTACACCACCGCGGCGTGCGCCAGGATGCCGTCGGTGGACAACCGGTCCAGCCAGTAGCGCAGCCGCGGCCGCCCTTCGGTCTCGACCAGGTCTTCGTATGACGGTCCGTCAGCCCCACGCTGACCACGTAATCCCCACTGGCCCAGGAATAATGCGCGCTCGTCGAGCATGCCGGTGTAGTCGGCGACAGCCAGGCCCTTGACGATCCGCGAACCCCAGAACGGCGGGGCGGGCACCTCGATATCGGCGGCGACATCGGAGCGTTCCGGGATTTCGACCGGCTCCTCGGCGGCTTTGCGCTGTGCCGCAATGCGTTTGGAGCGTTCGTGACGAGCCTTGCGCTCGGCTTCCTTCTTGCGGGCTTGGATGGCTTCCGGACTGTCGACGTCCGGTGCTTCGCCTCGCTTGGAGCTCATGATGGTGTCCATCAGCTTGAGGCCCTCGAAAGCGTCACGCGCATAGTGCACTTCGCCTTCGTAGATGTCGGCGAGGTCGTTTTCGACATAGCTGCGGGTCAGCGCGGCACCCCCGAGCAGCACCGGGAATTTTTCGGCGACGCCCCTCGAGTTCATCTCCTCGAGGTTCTCCTTCATCACCACCGTGGATTTCACCAGCAGCCCCGACATTCCCACCACGTCGGCGCTCTTGTCCTCGGCCACTTCGAGAATGGTGGCGATGGGCTGCTTGATGCCGATGTTGACCACCTCGTAGCCGTTGTTGCTCAAGATGATGTCGACCAGGTTCTTGCCGATGTCGTGCACGTCGCCCTTGACGGTGGCCAGGACGATGCGACCCTTACCCGAATCGTCATCGGATTTCTCCATATGCGGTTCGAGATACGCGACGGCGGTCTTCATCACCTCGGCCGACTGCAGCACGAACGGCAGTTGCATCTGGCCCGAGCCGAACAGCTCACCGACCGTCTTCATGCCGGCCAGCAGGTTCTCGTTGATGATCTCCAGCGGCGGCTTCTGAGTCATCGCCTCGTCGAGATCGGCTTCCAGGCCGTTACGTTCGCCGTCGACGATGCGTTGGGCCAGCCGCTCGAACAGCGGCAGCTTGGCTAGTTCGGCCGCGCGCGATTCCTTCGACGACGCCGCCGACACACCTTCGAAGAGGCGCATCAGCTCCTGCAGCGGGTCGTAGCCGTCGCGGCGGCGGTCATAGACCAGATCGAGCGCCACCGTGCGTTGTTCCTCGGGGATCCGGTTCATCGGCAGGATCTTCGAGGCGTGCACGATCGCCGAATCCAAGCCGGCCTCCTGACATTCGTGCAGGAACACCGAGTTGAGCACTTGGCGCGCAGCAGGATTGAGGCCGAAAGAGATGTTGGACAGCCCGAGCGTGGTCTGCACGTCCGGGTGGCGTTTCTTGAGTTCCCGGATGGCCTCGATGGTTTCGATGCCGTCTTTGCGAGACTCCTCCTGACCGGTGGCGATGGTGAAGGTCAACGTGTCGATGAGAATCGACGATTCGTCCACACCCCAGTTGGTGGTGATGTCGTTGATCAGCCGCTCGGCGATTTCGACCTTCTTCTCGGCGGTGCGCGCCTGGCCCTCTTCGTCGATGGTCAGCGCGACCACCGCCGCGCCGTGTTCGGCGACCAGCTCCATGGTCTTGGCAAAGCGCGATTCCGGGCCGTCGCCGTCCTCGTAGTTCACCGAGTTGATGGCGCAGCGACCGCCGAGGTGCTCCAAACCGGCTTGCAGCACCGGGGTTTCGGTGGAGTCCAGCATGATCGGCAAGGTCGACGACGTGGCCAGCCGGCTGGCCAGGGCCTTCATGTCGGCGACGCCGTCACGGCCGACGTAGTCGACGCACAGGTCCAGCAGATGCGCGCCGTCGCGGGTCTGGTCCTTGGCGATGTCCAGGCATTTCTGGTAGTCCTCGGCGATCATCGCCTCGCGAAAACCCTTGGAGCCGTTGGCGTTGGTGCGCTCGCCGATCACCAGGACCGAGGCGTCCTGGGCGAACGGAACGGCGCTGTACAGCGACGACACCGAGGGCTCGAAACTCACCTGGCGTTCTGGGCGTGGGGCGCCGACGACCGCGGCGGCGACTTCGCGGATGTGGGCCGGCGTGGTGCCACAGCAGCCACCGACCAGCGACAGGCCGAACTCGGCGATGAATCCGGACAGCGCCTCGGCCAGCTCGTCGGGCCGCAACGGATACTCTGCGCCCTTGGCGCCCAGCACCGGCAGGCCGGCGTTGGGCATCACCGACACCGGGATGCGGGCGTGCCGGGACAGGTAGCGCAGGTGCTCGCTCATCTCGGCGGGGCCCGTCGCACAGTTCAAGCCGATCATGTCCACACCCAGCGGCTCGACCGCGGTCAGCGCCGCGCCGATCTCACTGCCCAGCAGCATGGTGCCGGTGGTTTCCACGGTGACGTGGGCGAACACCGGAATGTGGCGGCCGGCCTGCTTCATCGCCCGCCGCGACCCCAGCACCGCGGCCTTGAGCTGCAGCAGGTCCTGGCAGGTCTCCACCAGAATGGAGTCGGCCCCGCCGTCCAGCATGCCGAGTGCAGCCTCGGTGTAGGCGTCTCGGATCACCGCGTAGTCGGTGTGCCCCAAGGTCGGCAGCTTGGTGCCCGGCCCCATCGACCCCAGCACGTAGCGCTTGCGCTCGGGGGTAGATAGCTCGTCGGCGACCCGGCGCGCGATGGTGGTGCCCTTTTCCGACAGGTCGCGGATCTTGTCGGCGATGTCGTAGTCGCCCAGGTTGGACAGGTTGCAGCCGAAGGTGTTGGTTTCCACCGCGTCCGCGCCGGCCTCGAAATAGTTGCGATGGATGGTTTCCAGCACGTCAGGGCGGGTTTCGTTGAGGATCTCGTTGCAGCCCTCCAGGCCGCGGAAGTCATCCAGCGTCAGATCGGCGGCCTGCAGCTGGGTGCCCATCGCGCCATCGCCCACCACCACGCGCTGCGCCAAAACGTCAAGGAGATCAGTGTCGTAGCGGGGCTTGTTAGCGGCAGTCACATGGCAAGAATAGTCGGCCTATGGATTTGCCTCAGTCGTTGACAGCGCTCTGACAGGTCAGGCCCAGGCCGTACGCTGATCGTGTGACCCTGCCGGATGCTGAGCCCGACGGCGGCCAAATGCTGCCCGAACTGCACAACACCGTCGTCGTGGCGGCGTTCGAGGGCTGGAACGACGCCGGTGACGCGGCCAGCGACGCCGTCTCGCACCTGGCCGACATCTGGGATGCGCGTCCCATCGTGGAGATCGACGACGAGGCCTACTACGACTACCAGGTGAACCGCCCGGTCATCCGTCAGGTCGACGGGGTCACCCGGGAACTGGAGTGGCCGGCCATGCGCATCTCGCACTGCCGCCCGCCAGGTAGTGACCGCGACGTCGTCTTGATGCACGGGGTGGAGCCGAACATGCGCTGGCGCACCTTCTGCGCCGAGCTGCTGGCCATCGTCGACAAACTCAATGTCGACACCGTCGTCATCCTCGGAGCGCTGCTGGCCGATACCCCGCACACTCGCCCCGTGCCGGTCTCGGGCGCGGCCTACTCCCCCGAATCGGCGCAGATCTTCGGGCTGCAGGAAACCCGCTACGAGGGACCGACCGGCATCGCCGGGGTGTTTCAGTATGCGTGCGTGGCAGCCGGCATCCCGGCGGTGACGTTCTGGGCGGCGGTGCCGCACTACGTGTCGCACCCACCGAACCCGAAAGCCACGGTGGCCCTGCTGCGCCGGGTTGAAGACGTGCTCGACGTCGAGGTCCCGCTGGGCGACTTGCCGACCCAAGCCGAAGCCTGGGCGCAGGAGATCAGCGAGATGGCCGCCGAAGACGACGAGCTGGCCGAGTATGTGCAGTCGCTCGAACAGCACGGCGACGCCGCCGTCGACGTCAACGACGTTTTGGGCACGATCGACGGCGACGCGCTGGCCGCCGAGTTCGAGCGCTATCTGCGCCGGCGCCGCCCGGGGTTTGGGCGTTAGTCGCCAGATCCGAGCCGAAGCATCGTGATCAGCGCCGTCGGCTCGCCTGCCAGGGTGGCCTCGATGAATCGGTTGACCAGCGGGCGCCAGCTGAGCCGCAGCATGGCACGGCGGATCGCCGACTGCGACGGCCCCGGCCACAGCCAGCCGGAGGCAGCCTGGCCGCTCTGTTGCTTGTCTTCCACCACCGGACGCCAAAGCCGTTCGTAGAAGGCCAGCGCGCGCTCCACCGATGACGTCTTGCGCAGCTGTTCGGACAGCACATAGGCGCTGGCCACGGCCAGCGAAGCGCCCTGCCGGCTCAGCGCCGAGACCGCGAAGCTGGCGTCACCGATCAGCACCACCCGCTTGCTGCTCCAGCGCGGCATCTGGATCTGCGCGACCTGGTCGTATTCGACCGCGCCGTCTTCCGGGCATCGATCGAGCACTTCGGCTACCAGCCCGCCCATCCCGGCATACTCCTCGCGCAGGGCGGCCCGAACGTCGTGCGGTGGGCTTGCGTCGACCGTGCGGTACACCGCCGTCACCGCGGTCCGGCCGTCTCGCAGCAGGTGGAGGCCGAGTTGGCGATCGGCCGTATCGGTGAAAACGACATGCTCGGCGGCTGACCCCCGAACGCCGGGAGCGTCCAGCACGAAGGAGGCGGAGCGGAATCCCGGGTATCGCAGATATTGCGGCTCCACACCGAATACCAGGGTCCGAACGGTCGAGTGGATGCCGTCGGCGCCGACCAGGAGGTCGGCATCCAGTTGTGCACCGCGTTGCAGTGTGACAGTCACCCGATCGTCTCGTTGCGCCACGTCGGACACCGTTGCGCCGAAGCGCAGCTCCACCTGTGGCGGAAGGTTGTCCAGCAACACCTTTTCCAGATCCGGGCGCATTACCCGGCACAGCCGGCCGTCGAGCGCCCTAGCGATCTGCCGGTAGGGCAGCGCCGCCCTTCGCCGACCGTGCCGGTCGATCAGGCTGGAATCGCCGAGGGGATAGCCGACCCGTTGGATCGCGGGCAAGACTCCGATGGCCTCCGCGGCGTCGTAACCGGCGCCATAGAAGTCGATCATGTGGCCGTGGGTGCGGGGACCGGAGGAGCGTTCGAGAACGACGACCTCGGCTCCGAGCGCCGACAACCGCTCCGCCAAGCTCAGCCCGGCGGTTCCGGCGCCGCAGATGGCCACTTTCACGGGGTCACCCGGGCGGATTCGACTACTGCTTCTCCGAAGCGTTGTCCAGAGCGTGGGTATACGCGCTGGTGGACCGACCGAGCGCGGCCGCCTCGGCGTCCATCCGGGGCAACAGCTCGGCGGTGATCTTGCGGATGGGACGTTCCCCGACCGACGTCGACAGCACCGGCTTGAGCCAGCGGAACAGGCCCACCCATCGCGGGCAGAAGATGCGCGTCTTGCGGCCCTCGATGCCCTTGACGAACGCTGCCGCGCACTTGTTGACCGACGTGGTGAGGTTCAGCGGCCAGGGCAGCCTCCTCAGAAGCTCGTCGAACGCGGGCAAGTCGGCCTTGGTGTCGCGGACCAGCGCGGTGTCGATCCAGGACATGTGGGCCGAGCCGACACTGACGCCGTGGTGGGCAACTTCCAGTCGAAGCGCATTGGCGAATATCTCGACTCCGGCCTTGGTTGCGTTGTAGGGCGCCAGACCCGGAGAGGCCGCGAACGCGGCCAGCGACGACACGATCAGCACGTAGCCACGGCGCTCGATCACCGCCGGCAAGGTGGCCCGCACGGTGTGAAAAACGCCGAGCACATTGACGTCCAGTACTCGCTTGAATGCCTCCGGATCGACCTGGAGCACAGACCCGTAGCTGGCTATTCCGGCGTTGGCGATGACGACGTCGATGCCGCCGAACTTTTCGATCGCCAGATCGGCCGCGGCCTGCATCGCGGACAGATCGCGGACGTCGGCCACGACGGTCAGCACCCGACCGTCGCCGCCCAGTTCGGCGGCAATGGTGGTCAGCTCCGCTGTGCCGATATCCGTGAGCACCAGTTTGGCGCCCTTGTTGTGCAGCCGGCGGGCGACCTCGGCCCCGATTCCGCGAGCACCGCCAGTGATGAAGACGACCTTGTCCTGCACCGATGTCATGGCCGAAAACGTACCATTGCGGGCCTAGAGGTCCACTCCTAACAGGGCGTCGATGGCGGTCGCCACCGATGTCGGCGCGCTCTCGTCGTGGCCACCGTATTCGAGGGCGTCGGTAGCCCAACCATCAAGTGCCGCAATCGCTTTGGGCGTGTCGAGGTCGTCGGCCAGGTAGCGGCGCACCCGTGCGATGACGTCGGCGGCGTCCGGACCGGCGGGCAGTGCGGTGGCGGTGCGCCAGCGTTGTAGCCGGCCTGCGGCCTCGTCGAGCACCTGGTGCGTCCAGAAGCGGTCTTCGCGGTAATGCCCGGCCAGCAGACCCAGCCGCACCGCCGACGGTTCGACGCCCTGCGCGCGCAGCGTCGACACCAGCACCAGGTTTCCGCGACTCTTGGACATCTTGTGGCCGTCCCAGCCGATCATCCCGGCGTGCACATAGTGTCTGGCGAATCGACGCTCACCGGTGACGCATTCGGCGTGGGCGGCGGTGAACTCGTGGTGCGGAAAGATCAGGTCGCTGCCGCCGCCCTGGATATCCAGCCCGCTGTTGATGCGGCTGAGGGCGATAGCGGCGCATTCGACGTGCCAGCCGGGTCGGCCGGGCCCGAATGGCGACGGCCAACTGGGTTCGCCGGCGCGGGCGGCGCGCCACAGTAAGGCGTCGAGTTGATCCGTCTTGCCGGGCCGGCTCGGGTCGCCGCCGCGCTGCTCGAACAGGGTCAGCATCGTGTCGCGGTCACAACCGGATTCGTAGCCGAACTGCACGGTGGCGTCGGCCCGGTAGTAGATGTCGGGGTAGTCCCCTATTTCCGGGTCGACCGTGTACGCGGCTCCGGACGCCAACATTTTTTCGATGAGCTCGACCATTTCGGCTACAGCCTCGGTGGCGGCGACGTAATCGTGGGGCGGCAGCACCCGCAACGCCTCCATGTCGGCGCGGAACAGCTTGACCTCGCGGTCAGCGAGCTCGCGCCAGTCAACGCCGTCGCGGTCGGCGCGCTCGAATAACGGATCGTCGACGTCGGTGACATTCTGCACGTACTGCACGTCATGGCCCAGGTCCAGCCACAGCCGATGGATCAGGTCGAACGCAAGATATGTTGCGGCGTGGCCCAGATGCGTGGCGTCGTAGGGGGTGATCCCGCAGACGTACATGGTCGCCTTGGGTCCGGGTGTCACTGGGCGCACCTGACGATCGGCGGTGTCGTATAGTCGCAGCTCCGGCCCGCGCCCCGGCAGGTTCGGAACCGGGGCAGAAGACCACGATCGCATGCCCTCGACTTTAAGCCCGGCGACTCAAACGTTACGAGCGGCCCGCGCAGCGGGCCGTTGAGGAGCCGGGCAATCAGACCCAGCCCGGCGACTCAAACGTTACGAGCGGCCCGCGCAGCGGGGCGCTCGGAGTGGCCAGCCGACGATGCGGGCGCGTAGCGGCGTTGTCACGAGCCGCGGCTTGGATGTTGGGCCGGGTTGGCTTGGGGGGCTTGGGGGGCGACCAGTTTGGGCCCGACGATGTCGCGGTCAGCACAGCGGCCTTGGCTGCAACGAGTGTGAACGTCGGGCTTTGATTGTGCAGCTATGGCGACCGATCTTGCGTGTCGACCGCCCTGCACGCACATTCGACGCCACCAGCTCACACTCGACGCCACGAGCTCACACTCGACGCCACGAGAAACGACAACTGTTCGACGGCCTACCGCCACGTTCGCCGCATAGCACCAAGCAGGACGGGTGCCAGCTCCTTTCGGCACATCAAGAAGTCGGGCAAGTAGGGGTCGAGTTGGTTGTACTGCAACGGCGAGCCGTCCAAGCGTGACGCGTGCATTCCCGCAGCGAGCACCACTCCGGCCGGCGCCGCAGAATCCCATTCCCATTGGCCTCCGGCGTGCAGGTAGGCGTCGGCGTAGCCGTCGATCACGGCCATCGCCTTGGCTCCCGCCGAGCCGATCCGCACCAATTCGATATCCACCGTCTGCTGGATGTAGTGCAGGATCGCCGGCGGTCGGTTAGCGCTGACGGCGACTCTGATGACGTCTGGAATGCCGGTGGGCGCGGCGTCGGCAGTGACGGTGTCGCTGCGGTACACGATGTTCCCGCGGGCCGGCAGTGAAACCGCCGCGTCGGTGATCTGCGGTCTGCCATTGGTAGTGCGCTGCCACAAGGCGACATGAACCGCCCAGTCGTCGCGGCCTCGGGTCGAGAACTCGCGAGTACCGTCCAACGGGTCGATGATCCACACCCGGTCGCACTTCAGCCGGACCAAATCGTCGTGGGCTTCCTCGCTGAGCACCGCATCACCGGGCCGTGCAGCTCGTAGCCGCCGCACCAACAGTGAGTTGGCCCGGGCGTCGCCGGCATCGCCGAGGGCCCACGGGTGGTCGAAGCCGACCTCGTCGCGCAGCGCCAGCAACAACTCCCCGGCTTCAGCCGCAAGATCGGCAGCTAGCTGCGCGTCAGTCAGGTCATCCGCAGCAGGACTCACCGATTCAGTATCGCGGAGCTAGGCGTATGCCCGGCAAACGGGACCGGACGCACCGAATCAGTCAGCCGAACACGTCGTCGACCACGAGCTCATCGGCGAGCCCACCGCGCGCGCTGCCGGATCACCGATCCCCGGCGCACCGAGGTCCCCGCACAGACTGGGCGCTGACACCGAAACCCTGAGCGCCCTGCCGAATACACCCCTTCACCCCCGCGGTTCAGCGGCATATGGGCCAATCCCCGATGACGGTGGTCAGCCCACACTCGCGTCGTCACACGGCCGCCCGGAGGACTCGGCGACCGCGGCGTGCGGGAGGCCCAGCTCGGCGACCAGCCGAAAATCCGGCGATTCGGTACGCGATAATTTCACGCATCCCGATGGGGCGAGCACGCTTTCACCCCGACGGCCGCCCCGGCCGGCGCCGACCCCGCAAACAGATGCTGTTCGGCGGCTATCCGGTGCGCATCGCGGACGAGCGCCCGAAAACCCTGGGCAAGAGACCCGCTAGAACGCCGGCCACGGAATCGGACGATGCCGGTTAGGTCCGGGCATCACCGGATTGTCCAGCAGGGCGCGCACCCGCCGCCGCAGCGCGGCGATTTCGGCGCTGGTGACGTGGTCGCGCAGCTCATCGGCGAGCGACCCGCGCAGGTCATCGGCAAGCCTGGCAATGGGCTCGAGCGTTGGTTCGTCGATTGGCTTGCCCGCCCACCCCCACAGCACGGTGCGCAGCTTGTCCTGGACATGCATGCACACGCCATGGTCGACGCCATACACCCGGCCGTCGATGCCACACAGGATGTGGCCGCCCTTACGGTCGGCGTTGTTGACCAGGACATCGAACACCGCCATCCGCCGCAACTGGTCGTCGTCGGCGTGCATCAAAACGACCTCGTCGCCGGCGTAGTCATAGGCGCGCAGCACGGGCAGATAACCCGGCCGCGCCTTGCCCGTCGGAAACAGGTCCACCAAATCCGGTCCGGGACGCGCCTCGGCGTCCAGGGAATCACCAGGTTGCCGCACCCACAGCTGCAACATGCCCGGCCCCGCCGGTCCGTCACGAATTACGGTGTAGGGCACGATGTTCCAGCCCAACGATGCCGACACCAGATAGGCGCTGAGTTCCCGACCGGCCAACGTCCCGTCGGGAAAATCCCACAGCGGTTGCTCGCCTGCCACCGGCTTGTAGACGCAGTGGACGGTCTTGCCGCCCAGCGTCGACTCGCACAGAAATGTCGCGTTGCTCGCCGAGCGGATGCGTCCCAGAACGGTCAGCTCGCCGTGGCGCAATACCTCACATTCGTCATTGCTCGGGTTCATCGTCAGACCCGAACAACAGGTCGCGCCGGTAGCCGTTGGTCCGCGCACAGATATGTCCCTGCGGATCCAGCGGTTCCTGACACAGCGGGCATGGCGGTCGGCCCGCCGAGATGACCCGGTTGGACCTGGTAGCAAACTGCCGCGCCGACTCCGGTGTCAGGAACACCCGTACCGCGTCGGGGCCCTCGTCGGTGTCGTCGAGTACCACGGACGCGTCGAACTCCGCGTCGGTGACGGCCAACAGCTCGACGACCACCGTCTGCGCCTCCGAATCCCAGCCGAGTCCCATCGTCCCGACCCGAAATTCGGCGTCCACGGGCATGATCAACGGGTTGAGGTCCTCAACCTCGGCGGGCTCCGGGGGCACCGGCGTGCCGAACCGGCGGTTCACCTCCAGCAACAGCGCGCCGATGCGTTCGGCAAGCACCGCGACTTGCTGCTTCTCCAGGACCACCGACACCACGCGGTCGTCATGAGCCGCCTGAATGTAAAACGTGCGGTTTCCGGGCTGGCCAACGGTCCCGGCGACGAAGCGGTCGGGTGTGCGGAATACGTGAATTGCGCGCGCCATGGCACCTCCAAAATACCGTGCAGACGCCGCCCGATCGACCGGGCCGGCGCAGGCCGGCCGGGCTAATCGGTAGACCCGCCGACCACCGCATCGCCGGAAGGCACCTCAGCGTCCGGCGCCGCCGGCTGCTCGCCGCCAGGCTCCGCCTTGGGCGGAGGTGCCGCACGCAGCCCCGCCGACAACCGCGCCCCGGTGTGGTTGACGTGCAGCACGAAGGGCCGCAACTCGGTGTAGCGGATCACACTTGCCGAGGCGGGGTCGGCGGTGATCCGTTGAAAGCTGTCCAGATGCATCCCGTAGGCATCGGCGATCACCGCCTTGATGACGTCGCCGTGGGTGCAGGCCAGCCATAACACGTCGCCCCCATATTCCAAGGCCAGCCGCCGGTCGTGCTCGCGCACCGCGGTCACCGCGCGGGCCTGCACCTGCGCCAAACCTTCGCCGCCGGGAAACACCGCCGCGCTGGGATGCGCCTGAACCACCCGCCACAACGGCTCGTTGGTCAGCTCGGCGATCTTGCGGCCGGTCCAGTCGCCGTAGTCGACCTCGGCGAGCCGGTCATCGACGAGCGGTTCCAGACACAGCGCGTCAGCCAGCGGTTCGACGGTGGCGCGGCACCGCAGCAGCGGCGACGCCACCACCGCCCGGACCGGTAAGTCACCGAACCGGTCGATCAGCCCGGTCGCCTGCTCCCGCCCCTTGTCGTCAAGGCCGACGCCCTCGGAGCGACCGGCCAGGATGCCGGCGGTGTTCGAGGTGGAACGGCCGTGGCGCAACAGGATGACGGTCATGTCGCGGACACCGTCCCGGTTGCCAATAACACGAGCACTCCCACGCCGACCACGATCCGATAACCCACGAACCAATACATGTTGTGCCGCAACAGGAAATGCAGGAACCAGGCCACCGCCGACAGGCCCACCACGAACGCGATCAGGGTGGCCACCAGCAGCTGCGGCCCGGTGGCGCTCATGCCCTCGGTCACCGGGTGGAAGGCATCAGGCAAGGAGAACAGCCCGGAGGCGAACACCGCAGGGATGGCCAGCAGGAAGCCGAATCGGGCGGCTAACTCGCGGTCGAGCCCCAGAAACAGGCCCGCACTGATGGTCGACCCGGACCGCGAGACGCCGGGGACCAGCGCCAGCGTCTGGGCGATGCCGACCACCACAGCGTCGCGCCAGTTCAGCTGCTCGACCTGACGGCCCTGCCGACCCAGGTATTCGGCGAGCGCGATCACCCCCGAAAAGACCACCATGGCCGTCGCCACCACCCACAGGTTGCGGACCCCGGAACGAATTTCGTCTTTGAAGAACAAGCCCAGAATGCAGATCGGGATGGTCCCGATGATGACGTACCAGCCCAGCCGATAGTCGGCGTTGCGATGCGACTTGACCACCAGCCCGTCCACCCAAGCGCGCAGGATCCGCACGATATCGCGGGCGAAGTACACCAGGACTGCGGCTTCGGTGCCCAGCTGGGTGACCGCGGTGAACGAGGCGCCGGCGTCGTCGCTGAAGAAGATTCGCGACATGATTGCCAGATGCCCCGAGGATGACACCGGCAGGAACTCGGTCAAACCCTGCACCACCGCCAATGAAATGACTTGCCACCAGGACATCGCCGCAACCGCAGACACGACGACGACCGTACCTGGTACGGCACACGGGTATCGGGTGCGACTAGCGCGAAACAGGTACCGCTTGGGCGACCGAATCGCGCACCGCGGCGGCCAGGCTGCGCTCGTCGGTGACATCGATGTCGACCAGACTGCGCACCGACCGCGCGACGACGTCTTCGGCCTGCGGGACCGGCGCGGTCAGGCGCGGCCGGTAGATTTCGACGACAAGTGACCGGTGTTCGATGTGGAAGGAAAAACTACGTCCGTCGCCGACCTGTCCATAGCCGCTGGCGAAGATGCCCGTCGACATGTCTTCGATAGCAAACTGTTTGTTTGCAACATGCCGGTCAGCGGTGACGGTCATGCCGCGACAATACCTCTCCAGTACCACTTTTCGTGGGCAACATGACGAGATCGGACGCGACTTGGATAGGCGAAATTCCTTGAGTTGTGGGACCCATGCTCGACGTTCGGAGGACCGGGCAGTTGCTGACAGCTACTAAGCAAGCAGTTCAACGCTGCCTTTGTGCCGCTGCCGCTTTGCTGACATTGGTGACGGCTTGTTCGTCGAACCCGCTGCACACCGCGCCGCCCACGATCCAGCCCGCGCAGCCCGCCGTGTCTCCGCCGGTTTCCCAGGCGCCGGCGGGGGTGATCCGGCCGTTGAGCGGCCATCCGCAGGCGGCGCTGTACGACAACGGCGCACGCCGGCTGGTGGTTCTTACCCCGGACGCCGATCCGTCGGCGCCATCGGGCATCACCGTGTTCGATGATGCGCAGACTCCATCGCGCGTGATCACCCTGCCCGGACCCGCGACCGCGTTGACCTGCGACGACCACGGCACCGCCTACCTGGCCGCCCGGGGTGGTTACCTCGTGGTCGACCTGTCCGCCGGCCGCATCGCACAGGTCAGCGTCGCCGACGCCGCGGGCACCGACTTCACCGCGATCGCCCGGCGCGCCGACGGCAAGCTGGTGCTGGGCAGCGCCGACGGCGCCGTGTACATCCTGGATTCCGAGAGCTCCGGCACTGCCCGGACAGCCAACCGCATCAAGATCTTCGCACGCGTCGATTCCCTTGTGACACAGGGAAATACCACCGTCGTCCTGGACCGCGGGCAGACGTCGGTGACGACGATCGGCGCCGACGGTCGCGCCCGGCAGGCACTGCGCGCCGGAGAGGGCGCCACTACCCTGGCCGCCGATCCGCTGGGCCGGGTGCTGGTGGCCGACACTCGCGGCGGCCAACTGCTGGTATACGGCGTCGACCCGCTGATCCTGCGCCAGGCCTACCCCGTGCCGCAGGCCCCGTATGGGCTGGCCGGCTCCCGCGAACTGGCCTGGGTATCCCAAACCGCATCCAACGTCGTCATTGGTTACGATCTCAGCACCGGAATACCCGTGGAAAAGGTGCGTTACCCAACCGTGCAGCAACCCAACTCGCTGGCCTTCGACGATGCGTCGGGCACCTTGTACGTGGTGTCGGGGTCGGGTGCCGGGGTCCAGGTCATCGAGCATGCGGCGGGTATCGCGTGACGGGCCGGCCCGCGTCGAGACGGAGCCGGCTGCCCGTGGGTTGGGATACCGATATGTCGGACGAATATGAGTGGGCGCCATTGCGCCTGCCACCGGAAGTGACCAGGCTCAGCGCGTCCACCCGGTTGTCCATCGAGGCCGAGTACCGTGGCTGGGAGCTGACACGGGTGCGGCTCTACACAGACGGCAGCAGACGGGTGTTGTTGCGCCGCAAGAAGTCTCGCCTGGACAACGCGTCGTCCGACCAGCCGGAACCGTGACGGCCGGCGACTGGCGCCAGGGCTGGATATACAGCCTGGTGCGGCGGCTGCTATTCCTCCTCCCGCCCGAGCGTGCCCACACATTCGTGTTCGCCCTGCTGCGTGCCGTCACCGCCGTCGCGCCGGCACGCCGGATGCTGAGCCGATGGCTGGGCCCGACCGATCCGGTGCTGGCCAGCACCGTGTTCGGGGTGCGCTTTCCCGGACCGCTGGGGCTGGCCGCGGGGTTCGACAAGGACGGCACCGGGCTGGACACCTGGGGCGCGTTGGGATTCGGCTATGCCGAGGTGGGCACCGTCACCGCGCGTCCACAACCCGGAAACCCGCCGCCGCGCATGTTCCGGCTGCCCGCCGACCGCGCCCTGCTCAACCGAATGGGATTCAACAACCACGGCGCCGGGGCGCTCGCGATTCGGCTCACCCGGCACCGACCCCGGGTGCCGATCGGGGTCAACATCGGCAAGAGCAAGGCGACGCCGGCCGGCGAAGCGGTTGACGACTACCGGGCCAGTGCCCGGCTGGTCGGTCCGCTGGCCGCCTACCTTGTGGTCAACGTCAGTTCGCCGAACACACCCGGGCTGCGGGATTTGCAGGCGGTGGAGTCACTTCGGCCCATCCTGACCGCCGTGCTGGCCGAAACCTCGACCCCAGTGCTGGTCAAGATCGCGCCGGATCTCTCCGACTCCGACATCGACGACATTGCGGACCTGGCGGTCGAGTTGGGTCTTGCCGGGATCGTCGCGACCAACACCACGGTGTCACGAGACGGCCTGGCGACCCCCGGGGTCGACGAGCTGGGCGCCGGCGGCATTTCCGGACCGCCGGTGGCAGCGCGCGCTGTCCAGGTGTTGCGGCGGCTTCAACACCGGGTCGGTGATCGCCTGGTGTTGATCAGCGTGGGCGGTATCGAGACCGTCGACGATGCATGGGAACGCATCACTGCCGGCGCGACACTGCTGCAGGGCTATACCGGGTTCATCTACGGCGGTGGCTTGTGGGCCAAGCACATTCACGACGGCATCGCCCGCCGGCTGCATGACGGCGGGTTCGCCCCGCTGGCGGACGCCGGGGGCCCGGCGGCCCGGAAGGCCGGGAAACCGCCCGGTTAGGCCCGGCCCCCCCCGTGCGCGGCAAACAGCGACGGCCCGGCGCCGTTTCAGCCGCTGCCAGCGGCGACCAGAAGGGGGAGCGGGCGGGAGCACCCCCCCCGCCGCGGGGCCGGCGGGGAGCCCCCACCCCCACCCCCCCCCCCCGTGGAACCCAGCGGCCCCGCCCCCGCCCTCCCCCCGCCCCCACTGGTGCCGACGCTTCCGAACCCCCCCCCGCCGTCACCGCCGGTGCCACCATTGCCGCCGGTGCCACCAGTGCCGCCGGTACCGCCGACGCCGATCACTGCATTGCCGCCGACTCCGCCGACGCCGCCGACAGCGGCGTCGCCGCCCTTGCCGCCTGCGCCCGCGCTGTTCTTGGTGCCGTTTCCGAACCCACCGTGGCCGCCGGTGCCGCCAGTGCCGCCCGTCCCACCGGTGCCGCCGTTGCCGGCGTTGCCGATGCCGTTGGAGGCGCCGGCCCCGCCGACCCCGCCGGTGCCCCCGGCGCCACCGGCACCCCCGCCACCCCCGGTACCGCCGACGGTTCCGGGGGTCCCAGTGCCGGTGGGGGGCCCGGCCCCCGCTCGCCCCCGCCGGTGCCCCCGGGGCCGCCGCCGTCGCCGCCGACCCCTCCGGTTCCGGCGGTTCCGCCACTACCGCCCCGGCCACCGGCTGCTCCGTTGGCGGTACTGCTGCTGGTGTTGTTGCCGCCGGCGCCACCGGTGCCGCCTTGGCCACCGGCGCCCCCGGTGCCGCCTTGGCCGCCGCCGATGCCGCCGATGATGCCCGCGCCGCCGTCACCGCCCACCGGCGGCGCCGCCATCGGTTCCGGAGCCCGCAGCTCCGGCGACGCCACCCGTGCCGCCCTTGCCGCCGTCGGCGCCGGCGGCGTTGAGCCCCGTCCCGGCGTTGTTGCCGCCCGCCCCGCCGGTACCGCCTTTGCCGCCGATGCCGCCCTGGCCACCCTCACCGCCGCCGACTCCCCCGATGCCCGCACCGCCGTCACCGCCCTGGCCGCCGGCGCCGCCACGGCCGCCCTGACCGCCGGCGGGCGGGGCGCGGCCGGAACTGCCGGCCCCGCCGCCGCCCCCGCTACCGCCGGCCCCCCCGGCGCCGCCCCTGCCCCCCGCGCCGACCACCCCCGCCCCCCCCCCATCGGGCCCCGCCCCCCCAGCCCCAGCCGCCCCCCCCCCGCCCCACTATCAACCAACTCGCCCCTCCCGGTACCGGTGTTCGTGCCACCGGCGCCACCGGTGCCGCCGTTGCCACCCACCCCGCCTTGGCCTCCTTGACCACCGCCGACCCCGCCGATGCCCGCACCGCCGGCACCGCCCTGGCCGCCGGCGCCGCCGCCACCGCCCTGGCCACCGGCGGTAGGAACGCTGCCGGACGTGCCGGCCTGACCGGTGCCGCCGTTGCCACCGGCGCCGCCGGTGCCGCCCCTGCCGCCGGTGCCGATCGCCCCGTGCGCGCCGTTACCGCTCCCACCGCCGCCGGCGCCCGCGGCGCCGCCCGCCCCGCCTTGACCACCGTCGGCCCCAGAGCCACCGCTGGCTCCGGTGTTCGTGCCGCCGGCGCCACCGGCGCCGCCTTGGCCGCCGACGCCGCCCTGACCACCTTGCCCGCCGAAGAGGTTCCCGGGAGCCGCGCCGCCGTCCCCGCCCTGCCCGCCGGCGCCACCCCTACCGCCCGTCTCGCCGACGGTCGGAACGCTGCCCGATGTGCCGGCCTGACCGGTGCCGCCGTTGCCGCCGGCACCCCCGGTGCCGCCCTTGCCGCCGATGCCGTCCGCACCGTTCAGACCGCCATCGGTCCCGGAGCCGCCGCTGCCGGAGAGGCCTCCGGTTCCGCCTTTACCGCCGCCGGCGCCGTCACCGCCACTGGTCCCGGTGTCGGTGCCGCCGGTGCCGCCGACGCCCCCTTGGCCGCCGGCGCCGCCCCGGCCCCCCTGGCCCCCCCCCCCCCCCGCCGACCCCCCCCCCGCCGTCCCCGCCCCGACCACCGGTGCCGCCGGCGCCGCCCCGGCCACCGGCGGGAGGCGAGGCGCCGGAGGTGCCGGCTTGGCCGCCTCCGCCGTTGCCGCCGGCGCCGCCGGCTCCGCCCTTGCCGCCGGCACCGTTCGCGCCGATGGCGCCGCCGTCGGTGGCAGAGCCGCCCGCGCCGGCCGCCCCGCCGACGCCGCCCTGGCCGCCGTTGGCGCCGTCGCCGCCGCTGGTTCCGGTGTTGGTGCCGCCGGCACCGCCGACGCCCCCTTGGCCGCCGGCGCCGCCCTGGCCACCTTGGCCGCCGCCGACCCCGGCGACACCTGCACCGCCGGCGCCGCCCTGACCGCCCGCGCCGCCCTGGCCCCCCGGCCTGCCGTCGGTAGGCGAGGTACCCGACGCGCCGGATTGACCGGCGCCACCCTTGCCACCGGCACCCCCGTCCCCGCCGTCCCCGGCAGTGCCGTACGCGCCGGCCGCGCCGCCGTCGGCACCGGCACCGCCGGCACCCGCGGCGCCACCGGTACCTCCTTGACCGCCCGCGCCGCCGGTACCGCTGCTGGTTCCGGTGTTGTTGCCGCCGGCGCCACCGGCGCCACCGTGTCCACCGACGCCGCCCTGCCCGCCTTGGCCGCCACCGACTCCGCCCACGCCCGCCCCTCCCCGCACCCCCCCGTCCGCCGGCCCCGCCCGCCCCGCCCCACCCACGCCCGCCGGAACGGCCACCCCCCGCCGCGGGCCCCCCTCCCCTGCCCCCCCCCCCCCCCCCGCCGCCCCCGGTGCCACCGGTGCCCGCGGCGCCCGCCGCGCCACCGGTGCCGCCCATACCCGCTGCACCCCCGGCGCCGCCCTGGCCGCCGGTACCTCCGGCACCGCCGTCGGTGGCGTCGTAGCCACCGTCGTCGTTGTAGCCGGCGCCTCCGGTGCCGCCGCGACCGCCCTGACCGCCGTGGCCGCCGCTGCCATTGGTCGCTCCGGCGACGGCGCTGCCGCCGTCGCCGCCCTGGCCGCCGGCACCGCCTTGACCGCCCAGGCCGCCGGTGTTGGCGACGTTGGGCCGCACGCCATTGGCCCCGTCGCCGCCTTGGCCACCCTGTCCGCCCTGCCCGCCGGCGCCGGCGGCGTGACCACCGATGGCGGTGGCCCCTCCCCGGCCTCCTTGGCCGCCGGCGCCGCAGTGGCCGCCCCTGCCGACACTCTGTCCCGGGAGGCCGCCGGTGCCCGTCGTGCCGCCGGCACCCCCTTGTCCCCCTGCCCCGCCGGTGCCGCCGGTGCCGGCGTTGTCGGCGCCGTCGTCGTGGTAGCCCGACCCGCCGGTGCCACCGGCGCCGCCGTCACCGCCCCGGCCGCCGGCGCCGTTGTTGGCGCCGTTGGCGGCGTTACCGCCCTGGCCGCCTTGGCCGCCCTGGCCACCCTGGCCGCCGGTGTGGCCGACGCCCGACGCCGGACCGAGCGCGCCCTGGCCACCCTGGCCGCCTTGACCGCCCTGGCCCCCTTGACCGGCGGTGTCGCCGAGGGTGGTGCTGACGCCGCCCTGACCACCCCGGCCGCCGTCGCCGCCGTCGCCGGCCGCACCCGCGCTGCCGCCGCCGCCCCCCGCCCCCGCCCCACCGCCCGCCCCGCCCGCGCCACCGGCACCACCCGTACCGCCGGCGGTGGCGCCGTTGGTTCCGTCGTCGGCGAACCCGGTGCCGCCCTGGCCCCCGCGGCCGCCGCCGCCACCGGCTCCCCCGGGGCCGTTGATACCCCCGTTCCCCCCGCCCCCCCGGCCCCCGGCACCCCCGTGGCCGCCGCGCCCCCCTGCGGCGCGGGTGCCGGAGCGGGTCGCGGCGGGTGCGCGGGTGCCGCCGCCGCCCCCGGTACCACCGGCCCCGCCCTCCCCGCCGGTGCCGGCCGCGCCGGCCGCCCCGCCGTCGGTCCCGGAACCGGCTGCCCCCGCCGCGCCACCGATGGCGACGCCTTGGCCACCGTCGCCGCCTTGGCCGCCCTGGCCACCGCCGGGGGGCGAGACGCCGGAGGCGCCGGCCAGACCGCTCGCCCCGCGGCCACCGGCGCCGCCGGCGCCGCCTTGTCCACCGGTGCCGGTCGCCCCGGCCCCCCCGCCGCCGGTCCCGGAGCCACCAGCCCCGGCAGCACCGCCGGTACCGCCCTCGCCACCTGCGGCGCCGCTGCCGGCGCTGCTTCCGGTATTGGCCCCGCCGGCACCGCCGTGGCCGCCCGCTCCGCCAACACCGCCCTGCCCGCCGGCGCCGCCGCCGACCCCGCCAACACCCGCACCGCCGGCGCCGCCTAGACCGCCGTCGCCGCCTTGACCACCCTGCAGGCCGGCGGTGGGCGCGCTCGGGTCGCTGGCGCCGGCTTGGCCGGCGCCTCCGGTGCCGCCGGTGCCGCCGTGGCCGCCGACACCGCCTTTGCCGGTGCTGCCCGCGCTGCCGCCGAATCCTCCGGCCGCACCACCCGCGCCGGCCAAAAGCCCCCACAAGGGACCGCGGCCCCCCCCCCCCCCCCCGATACCCCCGGCCCCCCCGGAGCCCCCGTGCCCCCCGCCGCCGGCGAGTCCGATGACCGCGCGCCCCCCGCCCCCCCCCGCCCCGGCGCCCCCCCCGCGGGCCCCCATCCCCCCCTGCTCCCCGGCGAGACCCCCCCCCCCCGCGCCACCGGCGCCGCCGCCGCCGCCGGCACCGCCGTGACCGCCGAACCCGAAGACGCCACCGGGGACGCGGTTGCCGGCACCCCCCGCCCCCCCGGGGGCCATACCGCTGGTGCCGTCGCCGCCGGCACCACCGGCACCCGCCGTTGCCGATCAGCCCGGCCGACCCGCCGGCGCCCAGCGCCGCTCCGGGAGCGCCGCTGTTACCACCGTTTCCGCCATCGCCGTACAAGATCCCGCCCGACTGGCCCGGCTGCCCCACCGGCCCGCTGGCCCCGTCGGCGCCGTTACCGACCAACGGACGTCCCAGCAACGCCTCGGTGGGCGCATTGATCAGGTTGAGCAGACCCTGCCCCGCGCTTTGCAAAGGCGCCGCGTTGGCGGCTTCGGCACCGGCATAGGCGTCCGCACTCGACTGGAGGGTCCGCACGAACTGGTCGTGATACGCCGTCAGGTGAGCGCTCAGGCGCTGGTAGGCCTGGCCATGCCCGGCAAACAGCGACGCCACCGCCGCCGAGACTTCATCGGCACCCGGGGCCGACACCGCGATCGTCGGGGTCGCCGCCGCCGCATTTGCTGAACGCAGCACCGAACCGATCCGTACCACGTCAGCCGCTGCCGCGGCCAATACCTCCGGGCTAGCCAACACGAACGACATCACTTCGATCCCCTTTGTCCGAGCGCCTTTGGCCACCGAGCCAGTACTCCACCGATCACCATCGCCCGATTCGGGCCGCAGTGCCCTCGGCCGAAAGGCGGATTCGGGGGTTGAAATTTTCTCCCCCTATTGGGGGAGGACAGCGCAGCCGCGACTCCCGGCAAGGGATTCGACGAGACGGCGCCGATCATCGAAACATATTGTGGCGCTGCATTGTTCAAGACACGTACCAGTCCGGACGCGACGCCGTAATCAGCACCGCACCAGGCGGCGGTCGAACGAGGGGCCAGTTGCAGATTGCCCGATATTCACTATGAATTGCGGTGATACCGCCCGGCGCCGCTGACCAATCTCGGCCAAGACACCACCGGCCCGCAGAGATACCACCAGACCACCCGCCGGTGCGGCGCCGCCATCTGCTTCGGCTTAAGGAGATGTGATGGATTTCGCGGGGCTACCGCCGGAGCACAATTCCGCGCGGATGTTTGCCGGCGCGGGATCGGCGCCGATGCTGGCGACAGCGGCGGCCTGGCAAGGGTTAGCCGCCGAGCTGGGCTCATCGGCATTCGCATTCGCATCGCAGACCTCCGCGCTATGCCACCCGGCCAGCGCCCGGCATGCCGCGCATTCCTTCACCGCCCGCGGTGCCGCTTTCACCGACTGCGCCGCCGCTGCCCGCGGCACCGCTCAGGACACCACCTGTTCCGCCGCTGCCGCCGCTTCCGCCCATGCCCGAGGCACCGCCCGTGCCGCCAGCGCCTCCATCACCCCTGAGGCCGACCTGACCACCAGTGCCACCGCTTGCGCCGCCGTCGCCTCCGTTGCCGCCCGTGCCGCCGCCGCCTCCGTCGCCGCCGACCCCTCCGGCACCGCCAACGCCTCCACTGCCGGCGAGTAGCCCGCCGGCGCCGCCGTTACCGCCGCTGCCCCCGATCCCGCCGGCCCCGCCGATTCCGCCGGTTCCGCCGTCGCCGGCGTCGCCGCCATTACCGGCAGTCGCGGTATTGCTCGCGCCCCCGCCGCCCCCGTTACCGCCGACGCCGCCGAAGCCCCCGACCCCGCCGGTGCCGCCTGCCCCGCCGGCGCCGCCGCTGCCGCCGTTGCCGCCCAACCGCCCGCCGTGCCCCCCGTTGCCGCCGGTGCCGCCAGCCCCGCCCGCGCCACCGGTAGCGCCGATCGCGCCGTCCCCGCCGTTGCCGCCTCTGCCGCCGATGGCCCTGTTGATATCGACCGATTGGGTGCTGGAAGTTGCGTTGCCGCCGGGTCCGCCGCTGCCTCCCGCGCCGCCTGGCGCTCCGCCGGCGGCTCCATTACCGCCTTTGCCGCCGGTGGCTTCGACGGTGTTAGGCAGGTTGTTGGTGTTGCTGCTCGTGGCGGTCGCGGCTCCGCCGGCCCCGCCGGCTCCGCCGGCTCCGCCGGCCCCTGCGATGCCTCCTTGACCACCGTTGCCGCCTTGGGCGCTGACGCTGTTTTGGCCGCCGTGGGTGTCGGTGCTGCTGGCATGAGCGTTGCCACCTTGGCCACCAGTGCCACCCGCCCAGCCGGTACCACCGATGCCCCCCGTTCCGCCGTCCGTACCGGTGGCCCAGGCATCTGTAGGGTTGGTGACGCTCACAGACGTGCCGGCAGTTCCACCGGACGCCGCAGCGCCATTGGCGCTGGGATTGGCTCCGTTCATCCCGGTTGCACCCGCTCCGCCATGCCCGCCATTGCCGCCGTTACCCCATAGACCGGCGTAGCCGCCATCGCCTCCGCGCCCGGCATTGCCGCCGTTGATGCCAGCAGCAGCCGCGCCGCCCGCACCGCCATCACCACCACTACCCAGTAGCAGAGCGTTACCGCCGGCGCCTCCTGCGCCACCAGCTCCGCCGGCCCCTCCCGCTCCGCCGTTACCCAGCAGCAGTGCGGCACCACCGGCACCACCAACAGCACCGGTTCCGCCGCCTCCACCGGGCCCGCCATTGCCATAAATCAGACCGCCGTTGCCGCCATTTCCACCCAAGGCCCCGGCCCCGCCAGTGCCGCCCGCGCCGCCGTTGCCGATCAGCCCGGCCGACCCGCCGGCGCCCCCCGCCGCTCCGGGAGCGCCGCTGTTACCACCGTTTCCGCCATCGCCGTACAAGATCCCGCCCGACTGGCCCGGCTGCCCCACCGGCCCGCTGGCCCCGTCGGCGCCGTTACCGACCAACGGACGTCCCAGCAACGCCTCGGTGGGCGCATTGATCAGGTTGAGCAGACCCTGCCCCGCGCTTTGCAAAGGCGCCGCGTTGGCGGCTTCGGCACCGGCATAGGCGTCCGCACTCGACTGGAGGGTCCGCACGAACTGGTCGTGATACGCCGTCAGGTGAGCGCTCAGGCGCTGGTAGGCCTGGCCATGCCCGGCAAACAGCGACGCCACCGCCGCCGAGACTTCATCGGCACCCGGGGCCGACACCGCGATCGTCGGGGTCGCCGCCGCCGCATTTGCTGAACGCAGCACCGAACCGATCCGTACCACGTCAGCCGCTGCCGCGGCCAATACCTCCGGGCTAGCCAACACGAACGACATCACTTCGATCCCCTTTGTCCGAGCGCCTTTGGCCACCGAGCCAGTACTCCACCGATCACCATCGCCCGATTCGGGCCGCAGTGCCCTCGGCCGAAAGGCGGATTCGGGGGTTGAAATTTTCTCCCCCTATTGGGGGAGGACAGCGCAGCCGCGACTCCCGGCAAGGGATTCGACGAGACGGCGCCGATCATCGAAACATATTGTGGCGCTGCATTGTTCAAGACACGTACCAGTCCGGACGCGACGCCGTAATCAGCACCGCACCAGGCGGCGGTCGAACGAGGGGCCAGTTGCAGATTGCCCGATATTCACTATGAATTGCGGTGATACCGCCCGACGCCGCTGACCAATCTCGGCCAAGACACCACCGGCCCGCAGAGATACCACCAGACCACCCGCCGGTGCGGCGCCGCCATCTGCTTCGGCTTAAGGAGATGTGATGGATTTCGCGGGGCTACCGCCGGAGCACAATTCCGCGCGGATGTTTGCCGGCGCGGGATCGGCGCCGATGCTGGCGACAGCGGCGGCCTGGCAAGGGTTAGCCGCCGAGCTGGGCTCATCGGCATTCGCATTCGCATCGCAGACCTCCGCGCTGGCCGGTTCGGCGTGGCAGGGCCCGGCGTCGGCGGCGATGGCCGACGCGGCCGCGACCTATGTGGGCTGGTTGAACGCGGCGGCAGTGCAGGCCGAGCAGGCAGCCTCTCAAGCCCGGTTAGCGGCGGCCGCGTTCGAGGCTGCGCGAGCGGCGACGGTGCATCCGGCCATCATCTCGGTCAACAGGGCCCGGCTGCTACGGCTCGTGGCCTGGAACGTGTTGGGCCAAAGCGCCCCGGCGATCGCAGCCGCCGAGGCCGAGTATGAGCAGATGTGGGCCCAGGATGTAGCCGCAATGTTCGGCTACCACGCCGAGGCGTCGGCGGTCGCCGCGGTGCTGACCCCATTTCCCTCGACGCTGCAGGCGCTGGCGGGCCTGCCCGGACCAGGGGCCGGAGCGGGGTTGGCCGGTACGAGCTTCGCCGGCCCGGCCCAGGCCGTCGTCGACCCGCTCGGTAGGGCGGGCTTGAACCTGGGATTCGCCAATGCGGGCAGCGGAAACGTCGGCAATGGGAACATCGGCAGCTTCAATATCGGTTCGGCAAACATCGGCAGCGCCAATATCGGCAGCGGAAATGTCGGCAGCACCAACCTCGGGTTCGGCAACACCGGTCCATCGCTGACCGCGGCCAGCCGCAATATCGGGTGGGGCAATACGGGCAGCACCAACATCGGCTTCGGCAACACGGGTAACGCAAACATCGGCTTCGGCAACACCGGCGACGGAAATATCGGTATCGGGCTGACCGGGGACGGCCGGGCCGGTCTCGGCGGGCTGAACTCGGGCACCGGCAACGTCGGCCTGTTCAACTCGGGCACCGGAAACGTCGGCATCGGAAACTCGGGCACCGGAAACTGGGGCATTGGCAACTCGGGCAACAGCTACAACACCGGCATCGGCAACTCGGGTGAAGCAAACACCGGCGTGTTCAACTCGGGTGTAGCCAATACCGGTGTCGCGAACGCAGGCAACTACAACACGGGTAGCTACAACCCGGGTAGCACCAATACAGGCGGGTACAACGGCGGCAGCTACAACACCGGCTTGTTGAACAGGGGCAACTACAACACCGGTGTGGCGAATACTGGCAACGCCGACACCGGCGCATTGATCTCGGGCGATTACAGCAACGGCCTGTTGTGGCGAGGAAATTATCAGGGCCTGATGGCTCCGGGTTTCGGCAACTCCACCGACATGCCGTCGTCGGGCTTTTTCAACACCGGTTCCGGTAGCGCATCGGGTATCGCCAATTCCGGCGCCAACAATTCGGGCTTCTTCAACGCATCGGACGTCGGGATCTCGGGCTATTACAACACCGGCGCGCTGGAATCGGGCGTGGTGAACTCGGGCAACACTGTCTCAGGCGTGTTCAACGAAAGCCTGCTGGATGTCGCCGTGCCGGCCGTTGTCTCCGGTGTCCTCAACACCGGCAGCGACCTGTCGGGCTTGCGCGGCGGCCCGTCGTCGCTGAACCTCGGCTTCGCCAACCACGGGGGCGCGAACATCGGCAACGCCAACATCGGCGACTCCAACTTCGGCAGCGGCAACGTCGGCAACAGCAACATCGGCAGGGGAAATGTCGGCGACACCAACCTCGGCAGCGGCAACATTGGTAGCACCAACATCGGCAACGGCAACATCGGCGACGGCAATCTCGGCTTCGCAAGCATCGGTATCGACAACTTCGGCTCCGGAAATCTGGGCGACTACAACATCGGCCCGGGAAACATCGGCGCCCACAATCGGGGCTTCTGGAACGCCGGTAGCTCCAATATTGGCTTCGCCAACGCCGGCGACTTCAATGTCGGTTTTGCCAATACCGGAAGCAACAACATCGGAGTCGGGCTGTCCGGAAACGGCGAAGTCGGGTTCGGTGCGCTCAACTCGGGCAGCGCCAACATCGGTTTGTTCAACTCGGGCACCGGCAATATCGGCCTGTTCAACTCGGGCACCGGCAATATCGGCATCGGAAACTCGGGCACCGGAAATTGGGGCATCGGGAACACCGGCACCGGAAATACCGGCATCGACAACAGCGGCAGCTTGAACACGGGTGTCGTCAACGCGGGCAGCACCAACACGGGTGTGAGCAACGCGGGCAGCTATAACACCGGTTTCGTCAACGCGGGCAGCACCAATACCGGCAGCTACAACACGGGTCAGCACAATACGGGCGGATTCAATCCCGGCAATTACGACACCGGCTACTTCAACTCGGGAAATGTCGACACCGGCGCTTTCAACACCGGAAACTACAGTAACGGCTTATTCGTTACCGGCGACAACCAGGGCCAGATCAGCGCCCATCTGGCCATCGATATTCCCACCGTCCCCATCGACGTCGAGTCCGTTAATCCCATCAATCAAACAATGGTCGTCGGCGGCCAGGAATACACCATCCCGGGCTACACCTATCCCAAGACATACTTCCTCGACGGCGACTTCTATCTGGGACCTGTCAGCATCTCGTCATCCACGGTGACCGGTCCCACGGTGACCATCGACATCGGCGGGCCGGCTACGTCCATCGATGCCACGGTCATCGGCGCCTTACAGGGCGGGACGATCCAGATCATCGACATCCCGGCGGCCCCGGGTTTCGGAAACTCGACAGCCAGCCCGTCGTCGGGGTTCTTCAACTCCGGCACCGGCAGCGCATCGGGCTTCGGCAACGCCGGCGCCGACACGTCGGGGTTCCGCAACCTGTCGGTCGGCAGCGGGGGCGTCTCGGGTTACCGCAATGTCGGCTCCCTGGAATCGGGCCTGGCCAATTGGGGCAACACCATCTCGGGCGTCTATAACACCGGCACCCAAGGGCTCACAGCACCGGGCAACCTTTCCGGCTACGCCAACACCGGCACCAATCTGGCCGGTGTGCTGCGCGACAGCGCGACCGGGACGGTGTTCAACGCAGGCCTGGCAAACATCGGAGCGTTGAACGTCGGCTTCGGCAATACCGGGGACTACAACCTGGGCAGCGGCAACGTCGGCAACCTGAACCTGGGCAGCGGCAACCTCGGCAGCACCAACCTCGGTAGCGGCAATATCGGCAACGGCAATATCGGCTTCGCCCACAACGGTGACGGCAATCTCGGCCTCGGCAACACCGGCAGCCACAACATCGGCGCGGGCAACACCGGCGACGGCAACATCGGCTTCGGCAACACCGGCAACGGCAACATCGGCATCGGGCTCAGCGGCGACGGCCAGACCGGGTTCGGCGCGCTGAACTCCGGCAGCGGCAACACCGGCCTGTTCAACTCCGGCACCGACAACGTCGGCATCGCCAACTCCGGCACCGGCAACTGGGGCATCGCCAACTCCGGCAACCACAACACCGGCCTGGCCAACGCCGGCAACACCAACACCGGCTGGTTCAACACCGGCCTGGCCAACACCGGCATCGCCAACACCGGCAACTACAACACCGGCAGCTACAACACCGGCGCCACCAACACCGGCAGCTTCAACCCCGGCAACACCAACACCGGCCTGTTCAACCCCGGCAGCTACAACACCGGCCTCGCCAACACCGGCAACATCAACACCGGCGCCTTCAACACCGGCAACATGGACAACGGCTGGTGGTGGCGCGGCGACAGCCAGGGCCTGATCGGCGCTTACTACGCGATCACCGTTCCCGAAATCCCGCTGAACGTGGTCGCAACCATTCCGATCGACATCCCCATCAAGGCGAGTTTCACCACCACCGTCTACCACGGGATAACGATCGACGACATCCCGTTCGGCACCACCGTCACACTCGGTCCCATCCCGGTCTTGCAGGGCACGGTCAATTCGCTGACCATTCCGCCGATTTCGGCCACCGGCCCCGCGCCGGCAATCCAGATCGGGAGTCCCGACGGTTCGACGGCGATCGTCATCCCCGTGTCCGCCAGCCTCGGCCCCGCCGACTGGACGATCATCGACATCGGCGGCGCCCCGGGATTCGGCAACTCGACCACCAGCCCGTCGTCGGGGTTCTTCAATGCCGGCACGGGCACCGCATCGGGCTTCGCCAACTTCGGCGCCGACAACTCGGGTTTGCTCAACGCCTCCTCGGGCAGCTCGGGTTACAAGAACGTCGGCGACCTGGTATCGGGCATGGCGAACCTGGGCAACACGGTGTCGGGCTTGCTGAACACGAGCACCCTGGACCTCGCGACGCCGGCAAATGTCTCGGGCGTGGCCAATATCGGCGCCAACCTCTCCGGGCTCTACCGCGACAGCGCGGCCGCGATGTCGACCTTCAACGTGGGGTTCGGCAACGTCGGTACGTTGAACGTGGGCTTCGGAAACATCGGCGACTACAACCTCGGCAGCGGAAACGTCGGGGACCTCAACGTCGGCAGCGCCAACGTCGGCAACCACAACGTCGGAGGCGCAAATATCGGCAACGTCAACGTCGGTTTCGGCAGCCACGGCCTGCATAACATCGGCTCCGCAAACCTCGGCAACGACAACTTCGGCCCGGCAAACTTCGGCGACGACAACCGCGGTTTCGCGAACGCCGGCAACGCCAATATCGGCCTTGCCAACACCGGCGACGGCAATATCGGTCTTGCCAACACCGGCAGCAACAACATCGGCATCGGGCTCACCGGCAACGGCAAAGTCGGGATCGGCGCGCTGAACTCGGGCAGCGGCAACACCGGCTTGTTCAACTCCGGCACCGACAATGCCGGCCTGTTCAACTCCGGCACCGGAAACGTCGGCATCGCCAACTCGGGCACCGGGAACTGGGGCATCGGTAACAGCGGCAGCACCAACACAGGCTTCGGCAATTCCGGAATGGTCAATACGGGGCTCTGGAATGCGGGCAACGTCAACTCGGGTATCGGCAACACGGGCGACTACAATTCGGGCAGCTTCAACGCCGGCAGCTTCAACACCGCCGGCTTCAACCCGGGCTCCTACAACACGGGTTACTCGAACACCGGTAGCTACAACACGGGATTGGCCAACTCGGGCAATGTCGACACCGGCTTGTTCAATTCCGGAAGTTACGACAACGGCATCCTCTGGCGGGGCGATTACCAGGGCCTGCTCGGCTACAACTACACGATCTATATTCCCGACACCGCCATTCCGGTGAACCTTGACGTGGAAATCCCCATCGATATTCCGATCAGCGCGACATTCGGCATCCTGACCATTGAGGGTTTCACCATTCCCAAGTACACCGCCGACATCACCGTGCTGGATGCCGGAACCACCCAGGCCATCAGCGTTGGCCCCCTCACGGTCTCGGATATCGTCGTCTCCCTGCCGCCATTAGCGACCACCATCGGCGGTCCGACCACCGCGATCGACATCACCGGTACCGGCGGCATCGGCCCCATCGCGATTCCGGTCATCGACATTCCGCCAGCGCCGGGCTTCGGGAACTCGACCGTGCTCCCGTCGTCGGGGTTCTTCAACTCCGGTGCCGGCAGCTCGTCGGGATTGGCCAACGTCGGCCCCAACAACTCCGGCTTCTTCAACGCCTCCGGAAACTCGGGGATCTCGGGCTACAAGAATGTGGGCGACCTGGTCTCGGGCATGGCGAACTTTGGCAACACCGTGTCGGGTTTGCTCAATACCAGCACCCTGGACCTCGGGACACCGGCCAATGTCTCCGGCGTCGCCAATGTCGGCTCCGACGTCGCGGGTTTCTTCGGCAATTCCGCCGTCTCCAACCTTGGGTTCGCCAACGACGGCAGCCTCAACGTGGGCAGCGGAAACGTCGGCAACCTCAACGTGGGCAGCGGAAACGTCGGCACCCACAACGTCGGTGGCGCAAACATCGGCAGCTTCAATGTCGGCTTCGGCAGCCATGGGCTGGACAATTTCGGCTCCGGAAATCTGGGCAACGACAACGTGGGCCCGGCCAACGTGGGCGATCACAACCTGGGCGTTGCGAACGCGGGCGACGGAAATGCCGGCTTCGCGAACACCGGCGACCTCAATATCGGCTTTGCGAACACCGGCAGCAACAACATCGGCATCGGGCTCACCGGCAATGGCAAGGTCGGGATCGGCGCGCTGAACTCGGGCAGCGACAACATCGGCTTGTTCAACTCCGGCACCGGAAATGTCGGCCTGTTGAACTCCGGAAACGGAAACATCGGCATCGCAAACTCGGGCACCGGCAACATCGGCATCGGGAATTCCGGCACCGCCAACACCGGCGTCGCCAACGCCGGCCGCCACGACACCGGTCTTTGGAATCCGGGCACCGGCAACACCGGCATTGCCAACGCCGGCGCCGACAACTCGGGCGCCTACAACACCGGCAGCACCAACACGGGTATCGCGAACCCCGGCAGCTACAACACCGGCAGCTACAACACCGGCAGCACCAACACCGGCCTGGCGAATACCGGCGACTACAACACCGGTGTGGCGAACACCGGCGACTACAACACCGGCCTGGCCAACACCGGCAATGTCGACACCGGCGCCTTCATCGCCGGCAATTACAGCAACGGCTTTTTCTGGCGTGGCGATTACCAGGGTCTATATGGCTTCCACGCCGGGATCTATATCCCCGAATTCCCGGTCCTGAATATGGGTATAGATATTCCGATCAATATTCCGATAAACTTGGATGCGGCGAATATTCTCGTCAACCCGTTCGCCATTCAACCGATTACCGTCAGCGTCCTGGGCTCGTCCTATCTCAGCATCACCTTCGGCACCATATCCATTCCGGCCCTCAGCGGTAATGGGCTCGCGGTCGACGCCCTCATCGGCGGGCCCGACACGTCGATACCCATCACCATCACCAGCGCCCTGGGCCCCATCGATATCACGTTCATCGACATCCCGGCGGCCCCGGGTTTCGGAAACTCGACAGCCAGCCCGTCGTCGGGGTTCTTCAACTCCGGCACCGGCAGCGCATCGGGCTTCGGCAACGCCGGCGCCGACACGTCGGGCTTGCGAAACCTCGGCGGCGCGGGCGTCTCGGGTTACCGCAACGTCGGCTCCCTTGAATCGGGCCTGGCCAATTGGGGCAACACCGTCTCAGGTGTCTACAACACCAGCACCCAGGGGCTCACGGCGCCGGGCAACCTCTCCGGCTACGCCAACACCGGCACCAACCTGGCCGGCGTGTTCCACAACAGCACGATCCCGGCCGGGCGCGTCCTCAATCTGGGCATGGCAAATGCGGGCCAACTCAACATGGGCTTCGGCAACACCGGCAACATCAACCTGGGTGGCGGCAACGTCGGTGACCTCAACGTCGGCAGCGGCAACCTCGGCAGCACCAACCTCGGTAGCGGCAATATCGGCAACGGCAATATCGGCTTCGCCCACAACGGTGACGGCAATCTCGGCCTCGGCAACACCGGCAGCCATAACATTGGCGCGGGCAACACCGGCGACGGCAACATCGGCTTCGGCAACACCGGCAACGGCAACATCGGCATCGGGCTCAGCGGCGACGGCCAGACCGGGTTCGGCGCGCTGAACTCCGGCAGCGGCAACACCGGCCTGTTCAACTCCGGCACCGACAACGTCGGCATCGCCAACTCCGGCACCGGCAACTGGGGCATCGCCAACTCCGGCACCGGCAACTGGGGCATCGCCAACTCCGGCAACCACAACACCGGCCTGGCCAACGCCGGCAACACCAACACCGGCTGGTTCAACACCGGCCTGGCCAACACCGGCATCGCCAACACCGGCAACTACAACACCGGCAGCTACAACACCGGCGCCACCAACACCGGCAGCTTCAACCCCGGCAACACCAACACCGGCCTGTTCAACCCCGGCAGCTACAACACCGGCCTCGCCAACACCGGCAACATCAACACCGGCGCCTTCAACACCGGCAACATGGACAACGGCTGGTGGTGGCGCGGCGACAGCCAGGGCCTGATCGGCGCTTACTACGCGATCACCGTTCCCGAAATCCCCGCATTCTTCAATGTTGCGATCCCCGTCGACGTACCGATCACCATCAGCATCACCGACATCGAGATCAATGCGGTCACCATTCCCAAGGTCTCGTTCAGCGGCTTGGACGACGGCATCGGCGGCAAAGTCGTCGGCTCCATCGGCCCCGTCAGTGTCTACGGTGCGCAGACCGGAGACCCCATCGTGATTAGCTTCGGCGACCAACCGGCGGTGGCGCTCAACGTGGGTAACCCCGACGGCACGACGGTGATCAACATCACTGGCACCGGCGGTCTGGGCCCCATCAGCATCCCGATCGTCGACGTGCCCGCGGCGCCCGGGTTCGGAAACTCGACCACCAGCCCGTCGTCGGGCTTCTTCAACGCCGGAGCCGGCAGCGCATCGGGCTTCGCCAACTTCGGCGCCAACAATTCCGGCCTATGGAACGTCTCGAACGCAATCGCGGGAAACTCGGGCTACCTCAACTACGGGTCACTGCAGTCGGGCGTGGCTAACTTCGGCAACACCATCTCCGGCCTGTACAACACCGGCACCGTGGGCCTCGAATCGCCGGCCAATGTCTCCGGTATTGCCAGCATCGGCACCGACCTCGCCGGGGTGCTTCGTGACGGCCCCACCGCGACGGCCTTCAACGCGGGCCTGGCAAACATTGGCGCCGGGAACGTGGGCTTCGCCAACATCGGCGACGTCAATCTGGGCAGCGCCAACATCGGCGGCTACAACCTGGGCAGCGGAAATGTCGGCGACCTCAACGTCGGCAGCGGCAACCTCGGCGGTACCAACCTCGGCAGCGGCAATATCGGCAGCGCCAATATCGGGTTCGCCAACACCGGCCCCTCGCTAACGCCCGCCGTCCACAACGTCGGTCTCGCCAACACCGGCAACCACAACGTCGGCGCGGGCAACACCGGCGACGGCAACATCGGCTTCGGCAACACCGGCAACGGCAACATCGGCATCGGGCTCAGTGGCGACGGCCAGGTCGGGTTCGGCGCGCTGAACTCCGGCAGCGGCAACATCGGCCTGTTCAACTCCGGCGCCGACAACGTCGGCATCGCCAACTCCGGCACCGGCAACTGGGGCATCGGCAACTCCGGCAGCTACAACACCGGCATCGGCAACACGGGCAGCACCAACACCGGCTGGTTCAACGCCGGCCTAGCCAACACCGGCATCGCCAACGCGGGCAGCATCAACACCGGCAGCTACAACACCGGCGCCAACAACACCGGCAGCTTCAACCCGGGCAACGCCAACACCGGCCTGTTCAACCCGGGCAGCTACAACACCGGCCTGGCCAACATCGGCAACTCCAACACGGGCATTGCGAACTCGGGCAACGTCGACACCGGCGCCTTCATTTCGGGCAACTACAGCAACGGCTTCTTGTGGCGGGGCGATTACCAGGGCTTGATTACCATTTCCTACTCGTCGACCATTCCCGAAATCCCGTGGCACTACGACGTGACTGCGCCCATCGAGATACCGATTAGCGGCAACGTCAACGAAATTACCCAAGAGGAGTTCCACATTTCCAGCATCCCCATAAAGGTCCAACTGCAGCAGACCATCTGCTTCCTGGGGTACTGCACCACCATCACCACAACCGTGTACGACGGCAGCGTGGGCGGTTGGGCACTCGGTCCGTACACGTTGCTCACGCCAACCGCCATAGACGACACCATCACCCAAACATTTGATCTGCCCGGCAGCGGAACGCTGGGTCCCTACACCTTCGGCTTCGCTTACCAGCAGAGTCCGGGGTTCTTCAATTCGACCACCGACCCGTCGTCGGGCTTCTTCAACTCCGGCGGGGGCGGCGCCTCGGGACTTTTCAATTCCGCACCCGGGGCGGTGTCGGGGCTGGCAAACGCTGTCGCGGACTCGTCAGGCCTGGGCAACGCCGGGGGAACCGGAAACTCGGGCTACCTCAACTACGGCGGGCTGGTATCGGGTTTTGCGAACCTGGGCAACACCATGTCCGGCTTTTTCAACACGAGCACCGTGGATCTGACACAGGCCGCATTCGACTCGGGCATCGGAAATGTTGGCATCAACCTCTCGGGAGTTTTCAACGACATCTTTGTGCCGTAACGGCGGGGGCTGGACCCGCGGAGCCAAGGGCGACGGGTGCCGCCTCAGCGGGCGTAGTCGGCACGCATCCGGTCACCCAATGCATTCGCGGCATGGACGCTATCCGATCCGCAGCATCCGGCAATAAGGTAAAGCGCTAACGGCCCCAACGATCCGAACGATTAAGCCCAGGTCGCCGATGAACAACACAGATATCGAGAAGGTTCTGCGCAAACAACGGTTGCGCTCATTGCAGGGCGGGTCGATACTCCGCGTCGGCGTCGCCGTCATCATGTTCAGCGCAATGCCGAGCGTCACCGATCCGGCTCGATTGCCCGAGCAGGCCGTGCTGCTGGGCGTCTATGCCGTCGTGACGATCGGCGCGCTGCTGCTGACCTATGCCGGCACGAGTCAGCTGCTCAACGACGACCGGGCCCTGTTGACCCTCGCGCTGACGGACGTCGCCGCGGTGTTCGGTTTCAAACTGCTCTCACCCGGCGGATTTATTCCGCTGTTGGTGATGGCGCTGCTGCCGCGCATGGTGGCTGTCGAGTTGTCGCTGCGGCGCGCCGGCGTCGTACTGGCCTGCGCCTTCGCGGTCTTTACCGCATCGGTTCTTCAAGATCCCATGATCATGCGCCGGATTGGCCCGTGGGAGACCGCGGTGATAGTGCTGGTGTACGGATTCATTTGCGGCACAGCCTTGTTGGTGGTGATTTTCCGGTTGCGCAACATCGACGAACTGGCCGAACTCACGACCTCGCGCGAAGCGCTACTTGCCGAGACCATGAACGCCTCGCAGGCCGAGCGCCGGCAGATTTCGGAGTTCATCCATGACGGACCCTTGCAGGACGTGCTCGCGGCCCGCCGCGACATCGCCGGATTCCTCAAGAGGTCCCCGGATGCACCCCTCGAACAGGCACTGGCCAGCCTGCAGGACGCTTCCCGGCTGCTGCGCGAGGCGACCTTCGAGCTACACCCGGCGCTACTCGACCAGGTCGGCCTGGCGGCCGCGGTGGAGAAACTGGTCGCCGTCACGGCAGCCCGCTCGGGCATGGCGATCACGACGGAGATCGATTACCCCGAGCCGAATGCGATCGACCCGATCCTGTTCGGGGTGATCCGCGAATTGGTGTCCAACGTGGCCCGTCATTCGCAGGCCAGCTCGGCGACTGTGAAACTGACAGTCGACGGCGAGGTCGCCCGCATCGACGTGGCCGATGACGGAATCGGGATAACCGGTGACGTCGCAGCGCGTCGTCTCGCTCAGGGACACATCGGTCTTGCCTCACACCGGGCGCGGGTCCAAGCCGCCGGCGGCACGTTGACCATCCTCGAGGAACCCGTCGGCGCGCGCCTGCGCGTGGAAGTGCCGCTTCGACGCCCGGCGGCGACCAGCGGCCCGGCGACGGTACCGCACGGAACCGATCGGCAGTCTCAACGGTGCTGAACGCCAGCCCGAGCGGTGACGCTCAGCCGTCTCGCCTTCGCCAGCGACCCGAAGGCCAAGACCCCGCCCATGCCGCGGGCCCCGACGCCGATGGCTATTCGAGCAGTCGACGCCGCATCGCCTCGGCGACGGCCGCTCCCCGATCAGAAACGCCAAGTTTTTCGTAAAGGCTGTGCACGTGCGTCTTGATCGTGCTGCGCGCCAAGTGAAGTCGCGACGCGATCTGCGGAACCGAGAGCCCGTCGGCCATCATCGTGATCACCTGGGCCTCACGCTCGGTCAGCAAGGTCGTCGCTCCCCGGCCCCGCCGTGTCACCTCACCAGCCAGCCCGCCGGCTATCCCGGCCGGCAGGTACGAGGCTCCTTCGGCGCATCTGACCACGGCGTTCACGATCTCGTCGCTGTCGGATTCCTTGGTCAAGAATCCCGAGGCGCCCTCGGCCAGAGCCTTGTATACGACGGGACTGTCATCAAACGCGCTCAGCAGCACCACGCGGGTGGGCAGTCTGTCGCGGGCTATCGCGTGGGTGACCTCGAGACCATCCAGCTCGGGCATCTTGTAGTCGAGAAGTGCGACCGCAGGCCGCAGTTGCCGGATGGCATCCAGCGCCGCGCGGCCGTCGGCCACCTGGGCGACGACTTCCACCCGCCCGCTGGACTTGAGGGCGCGCACGACCCCTTGGCGCATTACCGGGTGATCGTCGGCTACCACGACGGTGACTCGGTCAGCGGAATCTGCCATGCGATGCTCCAAGCGCTCTCGGCGACGCTATTCGGGCCCGGCCGAGTGCCGGACGGGCACCTCAACATTGTTGCTCCCGTGACAAGCAGACGCGACGATTTACCGGCACGGGTCACGCAGATGCGCCTCCGCGGTACGTCCGCGAAGCCCGTCTCGCCATTCAGCTCGACGGGCGCAAGTGAGCACAACAGGACTCACTTCGTGGTCCAACCTCCTGGCCCGGCGGCATCGTCGAAAGTTGGGATCGGTAGCAACGCCACCGAGGTGTTATTTCCGGCAACAGCGATGCCTAGCCGACAGAAACGAACATTCATGAAAATCACAGCGATAGCGGCAGCCGGCCTGATGGCCGGCATGCTGCTGACAGCAAGCCCGGCGCACGCCGAGCTAACGGCGAAACCACAGGCGAGCGGCGTCCGTCCGCTGCAGCCGGCCCCCCGTATGGAACCCGACCCCAGGTCGGAGGTGCAAGAGCTGCTGCAGCAAATCTCCGACCTGGACGATAGTTGGGACAGCCTCACGCCGCAGCAGCGCGTAGCCCAGTTACAGCAGCAGGTCACCGTCGTGGACCGGGGTACCCGTAATCTGCCTGCGGATCAGCAGCCGGAGGTGCAAGCGATGCTGAGCATGGCCGTTGTCAAGCTGGTCGATCTGGTCATGAAGGCTCAGCCTCCGGGTAGCCCCTGCTATTTCCCGTTCTGCTTGCCCGGGCTGTAGCGCCGCCCGTCCGACAGATAGTCGGCAACGAAATCCGTTGTGCGCCAATGCCACTCACTCCAATAGCGCACCATGTAATGACCTGCCCCGTGGATTCCCACCCACTGGGCATCCACCCCGCGGCGGCGTGCTCGAGTGGCCTGAGTACACGAACTGCCCGGGTCGGTCCACGTGTCGGCGGTGCCGTGCAGGACCAGGAGCCGGGTCCGCGCAGGGATCACGTCGCCGTCACCGCCTATCCACCACGGCGCCAGGGCCACCACTGCCCCGACGTCGCCTCGACCGGACAGCTGCGCGGCAACGCGGCCGCCCATCGAGTGGCCTACCAACACCACGTGTTGGGGTGCAAGCCGCTGTCGCACATCGTCGAGCGCCGCCAAGCCGTCGCGAACGGCATCCAAGCGCGGACTGTTCCAGCCGCGCACGCGGTATTGAACGCGTCGCACGTGCACGTCGCGCCCCAGCCGACGCCGCAACGCCCGGGTGAGGAACATCATCCTCAGGTTGGCCAGCTGCCACCACCTGGATGCGCCGTCGCTGCGGACCTTGCCGCCCGGCAGGACGAGAACACAGGCACGCGCGGCGCGACGATGTGGGGGCACATGTGTCATTCGGAGCCGAGGGCGGGGACGGACCGCGACGTCCCTGCCTTAATTCTCAGGTCTGTTGGTAGGTGCCGTAGATGACCGCCCGTGCGATCGCGTGCTGGAACAGGTTGAAGCCGAGAAACGCCGGGCTGGCGTCTTCGCTCAAGTCCAGTTTCTCGACGTCCACCGCATGCACCGCCACGTAGTAGCGGTGCACACCGTGCCCGGGCGGCGGCGCGGCGCCGACATAGCGGCGCATACCGGCGTCGTTGACCAGTGTCAGTGCGCCGCCGGGCAGCTCTTTGCCGGCGCCGGCGTCTTCGGGCAGCTCGGTCACCTCGGCCGGCAGGTTGGCCACTGCCCAGTGCCAGAACCCGGACAGCGTCGGGGCGTCGGGGTCATAGACGGTGACCGCGAAGCTGCGGGTCTCCTTCGGAAAACCCGACCAGCTCAGTTGTGGGCTGGCGTCCTGTCCGCCCGCGCCCATGATCCCGCTGACCTGTGCGGTGCGCAGTGGCTGGCCGTTGGTCACCGAGTCCGAGGTCAGGCTGAAGGACGGCAGCTCGGGTAGTGCGGCGTACGGGTCGGGCGGTGTTGTCATGCTCGGTCCTTTCGGGTTGTCGGCTCACTCAACATCAGCAGTGGGTCAAGAAATGTGTCAGCACCTCAGTGCCGAACTTCAGCGCATCCACGGGTACCCGTTCGTCGACACCGTGGAACAGCGAGGTGAAATCCAGGTCCGGCGGCAGCCGCAGTGGGCTGAAGCCGAAACAGCGAATGCCTAACCGCGCGAAGGCCTTTGCGTCGGTACCGCCGGAAAGCATGTACGGCACAATGCGGGCGTCGGGATCGACCGCCAGCACCGCAGCGTTCATGGCGTCGACCAGGTCGCCGTCGAAGCTGGTCTCATACGACGGCAGGTCCCGGATCCATTCCCGGGTGACGTCCGGCCCGATCAGCTCGTCCACCTCGGCTTCGAACGCCGCCTGCCGGCCGGGCAGCACGCGGCAGTCCACCACCGCCTCCGCGGTCGCGGGGACGACGTTGGCCTTGTATCCGGCCTTGAGCATGGTCGGGTTGGCGGTGTCGTGCAGGACCGCCTTGAGCATGCGGGCCATCGGGCCGAGTTTGTCGATCGCCCCGTCCAGGTCCGGCGAGTTGGTGTCGAAGGTGAGGCCGGTCTCCTCGCTGACGGCGGCCAGGAACTCGGCGACGGTGTCGGTGCACACCAGCGGGAATTGGTGCCGGCCCAGCCGGGCGACGGCTTCGGCGACGGCAGTGACCGCATTGTGGTCGTGCACCATCGAGCCGTGCCCGGCGCGGCCCCGTGCCGTCAGGCGCATCCACTGGATGCCCTTCTCGGCCGTCTCGATCAGATACAGGCGGCGGTCGCCGCCGTCGCGGCTCGGCACGGTCAGCGAAAACCCGCCGACTTCACCGATCGCCTCGCTGACACCGTCGAACAGATCGGGGCGGTTGTCCACCAGCCACTGCGCACCATACTTGCCGCCGTGCTCCTCGTCGGCGACGAACGCGAAGACCAGGTCCCGCGGCGGCACGATGCCGGCGCGCCGGAAATGCCGGGCGACCACGATCATCATGCCGATCATGTCCTTCATGTCGACCGCGCCGCGACCCCACACATAACCGTCTTCGATCGCGCCGGAAAACGGGTGCACGCTCCAATCGGCCGGTTCGGCCGGCACCACGTCCAGATGCCCGTGGATGAGCAACGCACCCCGGGAACCGGCTTGGCCTTTGGCGCCGGCCAGCCGGGCGAACACGTTGCCGCGGCCGGGCGCACCGGATTCCACATATTCCGGCTGGTAGCCGGCCTCGGCGAGCTGTTCGGCCACCCAGTGCGCGCACTCGGCCTCGCCTTTGGTGGTTTCCGGTTCGCCGGTGTTGGTGGTGTCGAACCGGATCAACCTGCTGACCACCTCGGCAACGTCGTCGCCCACACCTGTCACAGTCACCTTTCCTACCACTCTCGGGCACTCCCGGCCGCCTCTGAGGTGCCCCGCCCATCCGGATCCTCCGGCTGGAGGCGCGAGCCCGGTTGGGCTGAGGCGAGCCGATCGGATAGCCTTAGCTGCCAACTCATGCGAGTGGTTTTGTCCGAGTGGCGGAATGGCAGACGCGCTAGCTTGAGGTGCTAGTGCCCTACTAATGGGCGTGGGGGTTCAAGTCCCCCCTCGGACACGTCCGGCGACACGACTCAGGTCGGCCGTCGCCTTCACCTCCCGCAGCTGCGGATCGTAATCAAGGCGGAGCCCCAGACTCGCGTACACCTCGGCGCGTTCCGCCCCGGTCGCCGCACCGAGCACGGCTGACAGCCCACCCAGTTCCTCGACCAATTCGCTCATCTGTGCGGCAGACATGACGCGGGGCCGCTCCGCTTGCTCAAGACGGGCCTTCAGCTCGTCGCGCTCGGCGGTGCGGCGACGTAATGCGGCGGTCAAGTCCTCCACAGCCACGCCAGACTCGACAGCGGTAACCAAGGCGGCGATCTTGGCATTCACTTCGCGAAGCTGGCGCTGCAGGGCGGCGTAGCCAGTACCGGCTACCGGGTCCACGTCCTGCCCGCGTGCCAGGTCTTCCGGATCGGCCAGGGTGGCGATCCATTCGTCAAGTCGCGCAGTCACCTCGTCTTCACGGAGATAGACGGTGCGCGGATGATCACTCAGGTCCACAGGTATAGAACGCGACTTACCCAGCTCACAACGGTAGAGGATGCGGGTCGTTCGTTTCCCGACGCGAGCGGCGCCCTGCATCCGCCGTCCACACGCGGCACAGAACAGGAGCCCGCGCAGCGCATACGGCACGGTCGATTCTCTGCTGCACACGAGACCGGGACCACGCCGTGCCTGCGTCCGACGACGAACAGCCTCCACCAGTTCATCGGGAATCAGCGCTTCATGCGTGCGGCGGTCTGGTGCGATCCAGTCGGCCTGATCACGCCACCGCATACGAGTCTCGTACCCCGCCGCGACATCGTCGGGGCTGACCAGGACCTCGTATTTCTCCTGCTTGCCCCAAACACGGATACCGCGGTACGCCGGGTTGTCGAGTATCGCGCGGATCGCCGAATGGGACCAGCCTCGCGGGTCACGATGACGATTCCGCGCCGGGTCGTACTGGCTCGGTGACGGCACGCCATCGTCGGTGAGCTGTTGCGCAATGTAGCGCAGGCCCGCTCCGTCGGCGTACATGCGGTAGATCCGCTCGATGACCGGCGACGTCGCGGGGTCAGGTTCGAGGCGGTGAAGCCGCTGCCCAAGATTTGCCTTGGCAGGGTTTGGGTGCGGGCCGGCATCGACGAGCCGGTAACCGTAGGGTGGTCGACCACCGAGGTATCTCGACGTGTCCTGCGCGAGTGCTGACATCGCCGTACGGACGCGCACCTGGATTCGCGCGCGCTCTCCCTTGCTCATGCCGCCGAACAAAGTCATCACCAGGTCGTGTGCCTCAGAGCCGGGATCGACTGCACCGCCGACCTCGGGTACCCATAGGCCAACGCCGTAGTGCGTCAGGATAGGGAATGTGAGCGCGAACTGCGGCCCGTAGAACGCACGGGCGGGTTCCCCGATCACCACGGCATCAAAGTTATGGTCCGGACAAGCGACATCAGCAAGGAGACGTGATGCCTCCGGCCTGCGCTTCCATGGCAACGAACGGCTCTGTCCCACATCGAAGTAGTCAGCGGCAAGGACTCCGCCGTGCGGAGCGATCAGGTCTATGGCACGCCGCTTCTGCCAGCTGCGGCTCGCCTCCGGGTCTTGAGCGTCCTCCGTGCTCACTCGGCCATAGAAGGCGAACCTCAGGCTCACTCCACTCCCCTCCCTGATTCGAGCATCCGGTCCCGCACAGCTATTATCACGTGTATCAGCGCGCTGTTGGCCTCGTGCGGAAGTTGATAGTGGTTGGGCACGACAATTTCAACACCCCCCTCTGACATCGTCGGCGCATCGATTCGAGCGTCACGCTCAGACCGGGCGTGTGCTGTTCGGGATCCGTCAGCCATCGCTTCCCCCTGGCGAATCCCATCGTTGGTTGCGTGTTAGGCCACGGACTTCCATCTCGTCCGATCCGGCGGATTTCCATGCGTCGGAGGGCCGCGGAGTTCACGAGGGTACGGTCGCCGAGACTGGTGAGGCCGCCACGGTCAAACTCAAACACGATCGGACCATCGCCATCGGTGAGGTTGACGAAATCCTGGTGCGCAATGCTTTTCAGACGTTGTTCACGTGTCCACGTGGCGCGACGTTCGCGCAGCGCGGTCATCGTGGTGGAATAGCTGCGGGATTTGCTGGTTATGTGGCCCCGGTAGCCCAGGGTGTGCAGCCACCGGCCGACACCGGCCAGTCCCCTATCGGCGAGTTGGCTGATGGTGGTCAGGATCGCCCGGACGTGATCGGACACATCCAGGTCGGCGATGGCCTCGGTGCAGATGCGTCGTGCGCTGATCCCGACGTCAGCTAACGATTTGGTGACGTATTTCGCGAGGTAACGAGCTACGCCGCGGCCTGGCACCACTCGGCCGTGTGATGAATCCTCCTGCACAGCAGGGCTGTCCGTGCCAACGTGCCGGTTCTCGATGGGTTGGGTGTCGACTTGTTTGCCGAACCTGATCACCCGTGTCGCGCTATCTGAGGATGGGTCCCTGACTGTCATGGCTACGGTTCGAGCCGCCTGTTGGATGATGGTGGCCAGTTCAGTGGCCGAGAGGGGCGCTTGCCACTCTGGACCACCGCAGTTATCGCTGTCGCTCGGGTCGAGACGGATCAGGGCATGAATATGTGGAACGAGCCGGGCTTGCAGCTCGACGACTTTGATGAAGCTGACCTGCACCGCATCCGGGTCGGCGCCCAAGGCGCGTAGCTCGCGGCGCAGCGTGCGTCGCAGGGTGATGGTGAAGCGTCGCCACAGTTCTGGCATGTTCCAGGTGAACAGCACGTGCCCGATGTAGTCATAGCAGTCCGCGCAGATCGGCTGTCCCACAGGAATGTCACCTTCTCCGTGGCTTGTGCTGCACCACAGTGGTTTTCCATGCTGACAGCGGCGATAGCCGCCAGTCCCGTGGTGGTCGCGGCACAAACGGAGGCGCTTGTCGCCTGCACATGAGGTGGTGTGGACCGGCCCGTAGCTGGGTGCGGTCAGAGTAACGAACACCTGCGGGCGATCCGCCACTGCTTCTGGGATGTCGTGGTGCCCGCCGGCGGTGCCAGCGTGCACGAGTTGCCACGTGTCGCGCGCGTAGAGATCCGAGCACGACGGGCAGATCTGGGCGCGGCGGTTGTTGCATCGTGTCCACACCACCCGATCTCGGCCGTATTCGTCGGTGCCCGCGAGTTGGATGGGGTGGGCGCAGAAGCCGACGGACTCTGCACGCCGCCACCATGATTCGAAACCCACCGACGAAGCGCGGCGCACCATCTGATCCACCACCGCGGTCGTGTCGACCGTGGGCGGGATACCCGGCAGGGCGACCTGTCCCGGTGGTGTGGCGCTATGCACCGCTGGCTCCGCCGGAAGTCGGGCCACTGCCAGTGTTTCGGCCTTGATCACCTCCGCGATGACTGATTGGTGGCCGAAATATTCTGGCGAGGGTAATGATGTCGTGGTCGGTGACGTGAAAGGCCCGTGCCCGCACGGGTTCGGCGGTACCGTCGATCATCATGTAGCCCACACCGGGAGTGGTGTCGGGGATGTGGTCGCATTCCGCGCCGGCGTCACGGGCGCCTTGGCCCAGGACCATCGTTGTCTGACTGGCTTCGGTCAGCCGCAAACCGATGCGCGCGGTGAAGAGTTGCCGCACGGGCAGGGTGTCTTTGGCCGGATCTTGCACCGCGGCGACCACCGAAATGCCGACCGCGCGTCCTTGGGACAACAGCAGGCCCAGTAGCTGTTCGATTTCGGTGCGCACCTTGCGGTCGGTGACATAGGCAGTCAGGGCGGCGATCTCGTCAATTACGACAACGAACAGTGGCTCTGCCATCGTGGGAGTGTGCAGGCGCGTCTGGCCGCGCAGCCGGTTAGCGCGGGCGTGCATCACCTTCACCAGTTGGCGCAGCAGCTGCAGGGTGGTATCAGTGGCGTCGTGGGTGAACACCGTGAACATCGGCGCTCCGGCCCCCAGTTCCATGCCGCCTTTAGGGTCAATGACACACAGCCGCACTTGTCCGGTTTTCACCGCGGGGGCGATGCCGGCGATCAGCGACCACAACACCGAGCCCTTGCCCGCGCCGGTCGCGCCAGCCACGAGCACATGGTGACCGAGCAGAGGCAGGTGCCACCAGTGACGGGTTTCGGTCATCCCGACCCGCACCGACCCCACATCCACCGGGGTCGCCGCCGTGGGCATGGGCAGGGCAATCGGGTCGGCCAGCACGTCGTGGCGCATCAGGGTAATGCGTAATTCTCCGGGTCCGGTCGCGCGGATGGTGATCCGGTCCGCATGCCACGCCGCAGCCAGCGCCTCGGACTGCTTGTGCCAGTCGGTCAAAGACTGGCCGGTCACCACCCGCAGGTGCAGAACGTCGGTGGTCTTGCCGATGCGCGCCGACCGCAACGTCGGCACCAAACTGCGTTCACCCAGGCGGGCGTTAAGACCGTGCAGGGCGCACACCGATTCCCAGGTGCGGGTGTAGCGCCACCAGGTCAGCCATCGTCGCCGCACCGGCTCAGTCACCCAGTCGCGAAACGACCGCGGGTCCAGCCACGCCCACCCCGCATACGTAGCAGCGAAAGCAATACCGATGATCAGGCCGGGGCGTGGGCCATGGGTGATCGCTGTCGCCGCACTGGCGATGATCGGGATGCTGACGGCTGGAAACAGCACCGCCCACCACAGCAGATATCCCAGCGCCTTGCACAGTGAGAAGATGGGGTCGATAATCCAGTCGTCATTGTTCGCCCCAGAGTTGTTGCTGTTCTTGTTGTTTGATGCCATGACAGGCGTCCTCCTGTGAGTGAATGGTCGGCAGCGGCCCCAGTGCTGGGGCGCGACACCGATGAGTGCCGCGGCCCCAGCATTGGTGTTATTTCTGCGTGCGAGACGCCTGGTCACTTGACGCAGCCGTGGGGGTGATGGCGTCGGCTCGGAACGCCACACCACTGCGATCGCCTTGTGCCCATGGGATGGCCACCAACCCCGACACTGAGACTGGTTGCGTGACTGTCACTTTCGGGTCACCTGCGACGGTGACGTTGAGGACTTCACCGCCGGTGTCATCCAACGCCAGCACCTGGGTGGCAAACAGCGGCACCCCGGTGGCGGTGTCGACTTTCGGGCTGCCGGTCTCGAAGTTCAGCCTTGGCTCAGCCGCACGGGTGACGATGAACCGGGTTCCTGACGTATCGATTCTCAAACGCATTGCGTTACTGTCCTTTCTGGGGTTGTGCGCGACCGGACGTGGCGCAAATTCAGGACAGCGCCTGGCTTGTGGTCGTCGAAAGTGACAGCCAGCAACAACCAGTAACACCCAGACACGCGCACGCCCCGGCTGAGCTGCGCCGATGTGTCGGGCATGATCGAAGAGATGGCCGCAGTTGATCCGAATCGTGCGCTCAACGCGCAGCGGCTGCGGCATGCGCGCGAAGAGTATGGGTTCAGCCTTAATGAGCTGGCCGTTGAGGTCGAAAAACGTTCGCCGGCTACGCGGGGATGTCGAGATACCGGCGCGCGAGTCGTTGCGTCAGATGATCATCAGCATCGAGCGCGGCGGCGCGTTCGGCGATATGTGGCGCTCCGACCTCGCCGCGGCCTTTGGCCGCGAACCTGATGAGTTGTTTAGCGTGCCGATCGCCTCACCACTACCGCACCCTTTGCTGCTCCGTGTGCCAGTCGATGAGGACGTGTTGTCGGTGATCACCGCCCAGCGCGCAGCACATATACAGGCTGAGCACGCCTTTGGCCCTCAGCATGCGCGACCGTTGGTGGAGCGCGATCTCGATACTGTCGAAGCACTGATCAAGGCGGCGCCGCGGCGGCTCAAACTTGCTGTGGCCGAGGCGGCAGGAACGATCGCCGAAGTGGCCGGCTGGATCGCTCAAGACCTCGGTGATCATTCCGCAGCCCAAAATTTGACCCACAAAGCGTTTCTGCACCTTCGCATGGCCAGCCCCGAGGTCCAGGCGATGATCTTGATGCGGCAATCCAACATTCTGGCCCACAGCGAACCCGGGCTGGCCGTCGACCTCGCCGCTGATGCCGCCGACCTCATCGATGGCCGCGATCCGGGACGCCTCGCAGCGAGTGTCGCCCGCCAGCAAGCCCTGGCAGCTCTGCACAATGGTGACGAACGCAGCTTCTACCGCCACGCCGCCCACGCCCTCGACCTGGGCGATATCGAACCCGTGGAGGACGATCGGGCACCCTACGCCCACGCAGCATACGTAGCCAGTGATGTCGCATCGGGCTACTTGCGGCTCGGCAACCCAGACAGGGCTCTTGAGCTGCTCACCGACCACCACGCCCAATGGACATCTCAGCAGCACCGCGACCGCGCCGTCGCCGACATGCGACTGCTGCATGCCTACATCGCGGTCCGCGAATACCGTCTCGCCCTGGTGTTGGCCGACACCGCTATCCCCGCCTATTTGTCGGCACCCTCGCAGCGCGCGCGGCGCCACCTCGCCCGCGCGGGCACCCTCGTGCGGCAGCGCCGCCGCAGCGACTCCAATTCCGTACTGCAAGAACTCGCCGGACGCATCAAAAACGCCACCCAAGGAGTCATAGCGTGACCCGCGACATCATCCCCGACCTCACAACCACCGCCCCCGCCGCAACCAGCAAGATCGCGGTGCTGCCGGTCGGGGCTTTCGAACAGCACGGCCCCTACCTGCCGCTGGGCACTGACACTCTCATCGCCTGTGCCGTCACCACAGCAATCACCAAGCATCACAGGGTCCTTCAGCTGCCCCCAGTTACCTTCGGCTGCTCGCATGAACACGCCGCCTATCCCGGCACCGTCAGCATCGGCGCCGCCACCCTCACCGCCATCGTCACCGACATCACCCAGTCCCTCACCCACCAACAGATACGAGGGTTGATCGTCGTCAACGCCCACGGCGGCAACGCCGTACTCACCAATGTCGTCCAGCATGCCAACCAGTCCGCCCACCAACTCAAACTGGGGCTGTATCCGAGTCGCGAGGACTGGGCCGAAGCCCGTACCGCTGCCGGTGTCACCAGCAGCAATCACGACGACATGCACGCCGGCGAACTCGAAACTTCCATCCTGCTCGCCGCCCACCCCGACTACCTGCGCGACGGGTGGGCCAGCTCCGACCACAGCGCCACCGATCGGCGCTACCTGACCACCCTCGGCATCGGCCCCTACACCCCTACCGGCGTCATTGGCTACCCCTCACAAGCCACCGCAGCCAAAGGCCGCGCCGCCCTCGACCACCTCGGCCGTAACGTCGCCACTCTCATCGACCTCCTGGCACCGCCGCCTCAGCCCGAGCCGACCCCGTGAGGGCTTGGCCACCGTAGCGGACCGGCTATTCCACCGGGCATCAACATGCCGGACCTCGCAGGTGTGCACCCATTCCTCGCGGCTACCTGCGGGCTTCACTTCGCTCCCTCTGCTCCCGTCCGCTCGCGCTCCCGTCCGCGCCGGTCACTCTGCTTCGCCCTCCGTCCGCCGCCACCAACCGCCACTTGCCGCGACCGACTGCTTCAGCGCCGAACATCACACGACACCGCAGCGTCCATCGCTCCACGGCTACCTAAGCTGAGCAGCCCCAGCGTCACCGTCACCGCGAAACGGCACCTAGCGGGTGACTGACCTGCGATGTGAGAACTTTCTCTACTGGTATCAAGCCAAGGACGTTGAATAGCTTGGGCCGCAGCGTGACGCATTCGCATCGTGACATGAGCGCCGGCCTCCGCCGCATGAGGAATTTTGTCGCCCATCTGATTAGGATCTTGCAGTCCGGTTGGCGAAGCTTGGTGGAGCGATTCCCAGCACACAGATAAGACGCGCCAATTTTTGAGTGCTGATTTGCGTGAGAATTGTGAGTCTGACGCGGGCCATTCCAAGAGTAGTTAGCCTACTAGATACCTAGATGTCTCCCAAATTCGGCAGACACCCGGCGATTGTGGACGATGGTTATAATCGTTTAAATCCGTATTCCATCTTTGTCCCCTCGTACGGCTGTGGACCGGGTAGTCGGAGCACAAGCCGGGTCCCGCCGAACGGGCTGTCCTCCAGCGAAGCGGTGCCCCCGTGCAGTTCTGCTTGCTGGGCTACCAACGCTAACCCCAGGCCTGAGCCTGAATGTGACGTTTTTGATCCCCTTGTGAAGCGTTCGAACATCGCGGTGCGCTCTCCCTCCGGTATACCGGTGCCGTTGTCATCTATGACGATCTCTACCCCGTGACGGGAAGTGATCGCTGACAGCTGCACCTGCGTGGCCTGACCGTGTTTTACGGCATTGGCGACGGCGTTGTCGATCACCAATCGCAGCCCGGTCGGCAGACCCAGCATCAACACAGCGGGCGAAGGTCGCAACGTCACGTTGAGATCCGGGTAGACCCGCACTGCGTCATGAGCTGCGCGGTCGAGCAGCTCGGTGATGTCGAGCGGTACATGGTCGTCCGAGGTGCTTAGTTCGCCCTGTGCGAGCCTTTCCAAGGCGGTGAGGGTGGCTTCGATTCTGCTTTGGGTGCGCATAGTGTCTTCGGTGATCTCCTTGCGTTGCTCGGGTGGGAGATCGAGTGTGTGCAGTACTTCCAGATTGGTGCGCATCGCGGTAAGTGGGGTACGCAGCTCGTGGGAGGCAACTGCAGCGAAGTCACGGGCGGACTCTAGTGCGGCTTTGGTGCGCTGTTGTTCGGTGCCAATCCGGGCAAGCATGCCTTCGACCGCTTCAGCGATTTCGACAGCCTCCCACACGCCATCGACCTGAACCTCTTCCGGGCTGGATTGAGCATTGATGGCGCGGGCATGTTGGGCGAGTAGCCGGAAGGGTTTAATCATAATCGACCACATCCACGACCCGACGAGGAAGGTGCCGACGACGAAGCCGCCGCAGATCAACAGGACCCGCAGGTGAAGTTGCTTGATGGCTTGGCGGGCTTCTGTGATGGGAGCGCCAATTGCGATGGAGGCCCCGCCCGTGATGAAGGTGTGCACCCGGTACGGGATGCCGTTAACAGTGGCGGTGGTGTAGCCGTTGCCGAACTCCGGCAAGGTGACATTGCTCGGCTTGGATACCGTTATGCCGCCACTTCGGACGGTGCGTACCATGCCGTCGGGCATCGGCTCATCGACGTTGCCCTGATGTGTGCCGCCTAGCGCGCTGACATCGCCCAAAGTGCTTAACGAGTCCAGCTGACGATCCAGCTGGCTGTATTGATTGTTGGTGATGCCGACCCATACCCAGGCGCCAAGAAAAATGACGACAGCGACGACTGATAGCGCCGCGACGATAACAATGGTGCGCAAAGAGGCCACTGGCGTCGGCAGCCGCAGCACCCGCTGAAGGCGGTCGGGAATCGTCACTGTTGAACCCGCAAGACGAAACCCGCGCTCGGCACGGTATGTAGCAGTCTGGGTCCGCATACCAGATCGAGCTTGGAACGGACGCTGTCAATAAATGCATCGACGACGCGAGTGTCGGCGGCGAAATGACTATTACCCCACACCAGCTCCAGCAATCGTGCGCGCGACAGGATTTCGGTCGCATGTTGCGCGAGCACGGCCAGCAGGTCAAACTCACGTCTAGTGAGCTGTATCTCGATACCGTTGATGCTTGCGCGGCGCCTGCCAGTTTCCACCATGAGGGGACCGACGCTGATCGTCTCAGTCGAGAAATTAGTCACCAACACAGGTGGGCACAAAAGACCCCGCACACGAGTGACCAGCTCGCTCAATCTGTAAGGTTTGTACATAAAATCATCGGCGCCTTCCGCAAGTCCGGGAACGCGATCGCTGATCGCGCTGCGCCCACTCAGTACACAGACTGGTATCCGGTTATCCACAGACCGTACGGCGGAGACGACGCTGACGCCCCGCAGCGTCGGCTGATCAATGTCGACCACAACGGCTTGGGGTCGCGCCTCCGCGAGGACGCCCAGCGCATCAGGGCCGGTCTTCGCGCTTGTCATATCAAAGCCAGACAACCGCAGCCCACGTTCCAAGGAAGTCAATACATCCTCGTCATCGGCTACTACCAAGAGGCTTGGTGTGGGTTCATCGTCCATGAGGACATTTTGCCCGATCGTCAACCTTTTGAGCGCACATGCTCCTTACAGTTGAGCGATTGGTTTCTAGGTCCGCAAGGCTGTCGGGACGCCCGGTAATCGCCGCATACGAGCGTAGGTAACCTGGCTGCAGGGTTCATGGTCGGCCGGTAGCGTGCAGCCTCGTGGCTTGCTGTGCCTACTCCGCGTCTTACCGCGTCCTTGGCAGACAAAATTTGACCAGTGGTCGCAGTCACCCGCTCGGCATTTCACTGTACCGACGCACAGCTATGAAGTAGCAAGGGGTCAAGTCCAGGGACGTGGTGTACGACGTCGATCGTGTGATTCTTCGATTTTGTGATTTAGGCGGTCAGTGCTGTGGGGGTGTTCTCCTGTTCTGTCGGTGTGGTGGTGGTCGGGCGGGATTTGCTGAGGACGTCGAGGCCGAGGTAGCGGCGTGATTCGGCCCATTCATCGTGTTGTTCGGCCAGCACGGCGCCGACTAGGCGGATCAGGGCGTCACGGTCGGGGAAGATGCCGACAACGTCGGTGCGACGCCGAATTTCCTTGTTGAGCCGCTCTTTTATCCGGCCCTCAGGGTGGAGGTCAACCCGGTGTGGGTTCGGCTTCAACGATCGAGGCGTTGGAGATGGTCGGTGAGGGCATGGGCTACGCGGTCGTGGCGGGCTGCTTCGTCGGTCCAGCCGCGGTTCTCCGCGTCGGATTTGAGGGCTTGGACGTCGGCGAGTTGGTTAGTGAGGGCGCCGCGGAATTCGGGCGCGGTGATGTAGTTGTCGCAGGTTTCGCAGATGTTGGCATATGGGCAGGCGCCGGCGGTTGGGTGGCGCGCGCAGTAGCCGTGCCCGACACGGGTTTTCAGCATCTCACTGTGTAGCCAGCTGACCTTGTCGGGCAAGATGGGTCGACCGACCGGGGTGAGAGTGAACTGGCGACGCATCTTGCCCATGGCGTCGTCGTAGGCGGCGCGCAGGGTTGGCGAGGCAAGGGTGGCGTAGCGGATCGTCATCTGCGGTGTGACATGTCCGAGCAGCGCCATCAACGCTTGCATACTCATTCCGGCGTTGGCGAGTTCGGTGGCCCAGGTATGACGCAGCTGATGAGGCGTGACGACGAGGATGCCGCCGTCGGGTCCGCGTAGCCCTGAGGATTGGGCCGCGGCCAGCAGCCCGTTGCGCAGTCGGGTGTAGCCCAGGCGGCGGCCGTACTGGGTGAACAGGAAGTCGGTGAGCACGCCGGTGCGTGGATGGGCCAGTGGCCGGTGTGCGTCACGGTGGGTGACCCATTCGTCGAGCGCAGCGGTAGTGGCCGCCGATAGCGGCACCATGCGTTCGGTAGCCAGCTTGCCCAGCGGTACCTTTAGCCAGGTGCCAGCCGCCCCGTAGTCGATGATGCTGCCCAGTTCCAGGTCGAGCAGCTCACCCACCCGCAGCCCCGCTCCGCGCAGCACGGTCAGCCCGATACGAGCGAATGAATCATCTAGACGGGCAACAGCATTCATCACCGCCGCATCGATGTCAGGGGCCAGTGCCCGCGGCAGCGGCTGGTCAAGCTTGGGAACGTCGGCGGCGAAGACCAGTCGCCGCGGCGGTGCTTCTTCCCAGCCCCAGGCGGTGATGTCATCGAGCAGGTTGCGCAGGCTTAGCACCGCCGACTGGGCAACCGCAGCCGAGACGGTGCGCCCGGCGCCGGCGGCGGCACGTTGCCCGCGCCAGCCGCGGGTGCGGTTCCAGGTCAGATAGTCCTCGATGCAGGCGCGGTCGAGCTCGCGCAGGCTGGTCAGCTTCGAGTGGTGGGCGGTGAGGTATTCGACGAACGGCAGCAGGTCATTGATCAGCGATTCCACCGATTTGGGCCGCAACACCGCGGCTCGGACCCGGATATAGCGCAGCAGGGTGTCGAGGATCGGGGCAGCCATAGCCACGTCGGTGAAACGTTGCTCGAGGCTGCGTGCCCACGGTCGTCGTCGCGGAGCGGCGTCGAGGACCCGGACCTCGTAGAGCAGCTGGCGCAAGCTGGCCAACCGCGCCCGGTAGGCGCGCCGTGACGATCGCGGGATTGAACTCGCCGACAACGCACTGTCGAATTCATCGATCGCCTGCTCGGTGAGGTCAGCGACCAGCCCACCATGGCAAGCCACCAGCACCGCCAAGCACTCGCCGAGCACAGTTTCAATCCAGGAACTGCTCCAGCCCAACCGGTTTCCCGCTTCACGCATCGCGGAGAACCCGGCCGAATCACGCATCTCCACCGCGGCACCGAGCCCGGTCAGCTGCTTAATGACGGCCAGCTCAACATCCAGCCGCAACCGGCCGGCACCGATCGCATAGCACAGCAGGGGCCATGCCCCACTCGACCGAAGCTCGCCAGCCCGCTCAACCGCCGGCAGAGCCATCCACGCCGCCAGATCCGGGTGACGAGCAAGAAATTCCCGTGCGGTTCGGATCCGGTCCCGAATCGCCCGATCACTCAAGCGCAGGCGAGCGACGTGGTCGAGGTAGTCACTCAACAAAGTGCCGGCGTCAATGGAGTCCTGAACCGTAGCGACGGTCATCGCCGTGCTCCGGCCAAGGAGGCGCGGGCGGCACCATATTCGGCGGCGAGCTGCTCCAGTGACAGGTGCACGTAGCGGGCCGTGGTCTCCGGTGAGGCGTGTCCCATCAACGCCCGTAATGCAAGCAGATCAATTCCCGCAGAAGCCAATTCGGTACCATAGGTATGGCGCAGCCGATGCGGACGCACCCGGATGGACCCGGAGAGTTCACGGTGACGGCGAAACAAGCTGCGCAGCCCTGCCTCACTAACCGGCGCCCCCGTCGTCGGACCGCGCAGCACCACGAAGCACTGCGGTGTCGACAGCCCAGCCGGGCGCTCCAACCGCAGATAGGCAGCAACCTCAGTGAAGAATGCCGCATCGACCGGCACGTAGCGTTCCTTGCCGCCCTTGCCGATCACCCGCAGCCGCCGCCGCCCCATGTCCACATCGGCCAGCAGCAGACCGCGCGCTTCCGCCGACCGCAACCCGCCCAGCAGCATCGCCAGCACCATGGCCCGATCCCGATGTGACCCCAGCGTTGCGACAAATGCATCGATGTCGCTGGCCGGCAACGATTCCGGAAGCAGCTGCGGTTGGCGCACCAACCTGCCGCCAGGACGGGCACGCCCAGGACCCAGATGACCTAGCAGGCCGCGCTCCGAGCGGCGCAGCCCTTGCCCACGCCGCGGCGACGGGACCGGGTTGTTCCCACGGCGACCGGTCATCGCCAGGTACTCGAACAAGGCGCGTACCGCCGCCACCCGACGGTTCACCGTCGAGGCTGCAGCTGAGCCCGGCTGGGGCCGACCGGTGCGGCGTACCCCTTGCCAATCGATCCAGTCGAATACCAGTGGAGCCTGCACTTCGGACAGCGTCACATCGCGCTCAGTGAGGAACCGCGCCAGATTCGCCACGTCGAAGGCATACGCCCGAACCGTCGCCGCGCTAAATCCCCGTCCGGCCAAATGCGTGAGAAACGCATTGGCCGAATCCAACCCCTCCCAATCCCCACCGAGCCGATACCCCTCATCGACGCGCTGCACCCGCACCGTCATCACTCGACCTCCTGATCTCGGGGCCGCCCTCAGCATCTACCCGGCTCTGGGAACGGTCCCGGATCTCACGCCGCAGTCAGATTCGTGTCTCCTGAGGGCCGGTTAACGGATAGGGGGTTGTTGGACCAGATTTGGCGCCAGATCTGCTTGGGAAAAGCAGTGAACGCCAGCAAGTCCGATCGGGCGGCTTCGAGGTGATCGGCGACCTTGGGCAGCTTGTCGGCCAGGGCGTCGATGATCCGATCATATTGCGCAGCAACGGATGTGGCGTCGGGCTGATCGAACACCGAATGCAGCAGCGTCTTGACCCAGGGCCAGGAGCTCTTGGGGGTAATGGCCATCAAGTTGGTGGCGTAGTGGGTGCGACACCGCTGCCAGGATGCTCCGGGCAGGGTTGCCCCGATCGCGGAAAGCAACCCAGCATGGGCGTCACTGGTGACCAATGCCACCCCCGATAGGCCGCGGGCGGTCAACGAGCGCAGAAACGTCAACCAGCCGGCGCCGTCTTCGGCGGTGCTGACATCGATGCCTAAAATTTCGCGGTAACCCTCGGCGTTGACCCCCACCGCGATCAGCGCGTGCACGTTGACCACGCGGCCGGCCTCACGGACTTTAAGCACCAGGGCATCGGCGGCCATGAACGTGTACGGGCCAGCATCGAGGGGACGAGTCCGGAAGGCTTCCACGGCGGTGTCGAGCTCTTTGGCCATCACCGACACCTGCGACTTCGACAGGCCGGTGATCCCGAGAGTTTCGACGAGTTTGTCCATCCGCCGCGTGGACACCCCGAGCAGATAGCAGGTCGCCACCACGGTAGTCAGGGCCCGTTCGGCGCGTTTGCGGCGTTCCAGCAGCCAGTCCGGGAAGTAGGAGCCCTGGCGCAGCTTGGGGATCGCCAAATCCAAACTTCCTGCCCGGGTATCGAATTGGCGATGCCGGTAGCCGTTGCGGGAGTTGGTGCGCTCACTACTGCGTTGGCCATAGCCTGCGCCGCACAGCGCGTCGGCCTCGGCGCCCATCAGCGTGTGGATGAACGTGGCCAGCAGTTCGCGCAGCACATCAGGATGGGTGGTGGTGAGTCGTTCGGCCAGCACTGCAGGCAGGTCGATATCGTGGGCAGCGGTCATCGCGTCGATTCCTTTGCTTGAGTGACTTTGGACGGTCTCTCGAAGAATCACGCGATGACCCTCATCTACCCGGCTACGACACGCCGGTCCTCAACTCACGGCCCGACTCGTACACCACCTTGGTGGACGCAACCTAGCAAGGACACTGAGATGGCGCGCCGACCCACCTATAGGCTGCCCTGTACGCTAGGCCACCCGTTTGAGCCACCACGGGCGGCGAAGGGAGGTCAGTGGGCGAGGTAGGTGAACGAGCAGTCGTTTGCGGGGCCGGTATGGCGGGGTTGCTCGCCGCTCGCGTGCTATCTGAGTACTACGCCAGAGTGACGCTTGTCGAACGAGACAAGTTGCAGGCAGGTCCCGTCCAACGTGACGGAGTGCCTCAAGGAAGGCATTTCCACACGCTCTTAAGTGCTGGTTCTCAAGCACTCGGTGCTTTGCTCCCCGGATTGCTTGACGAGCTTGTTGCTGCTGGCGCGACTGTCTGCGACGAGGGCGACTTTTCACGTGTGTCCATACGGATCGGGGGGCATGAGCTCAATCGGTCTGGTAAATTTGCCGACCCTGCCTCGGTTGTCATTTACCTTGCCAGCCGCCCGTTCCTGGAATCCCACCTCCGACGCAGGATTCGCGCCATCAGTAACATTGAGGTCGTTGATGGCCATGACGCCGTTCAGCCAATTGTAGGTCAAACGAACCGCATCATCGGCACGCGAATTGCTAACCGCGACACCGGCGTTCAAAGAGTTCTTTCGGCCGACCTGGTGGTTGACGCGATGGGCCGCGGCGCACGTACACCAGCATTTCTCGATGGCTTGGGTTGTCAGCGGCCGCCCGAGCAGCGCTCCATTATGCAGGGGAGCTCCTCGAGTCAGTTCCTTTGCATTCCGCCCGACCTAGTTGGCGAGAAAATGACCATGGTTTTCCCAAGACCAGAGCAGCCGACCGGCGGGGGGCTCCTGGCCTACGAAAACGGCACATGGATATTGACCATTGGCAGGCTGGCAGGACGTGAACCACCCACTAACCTAGCCGGCTTGATCGAATGCGCTGAACAATTTGCGCCCCGCCCGTTGGTAGAAGCATTGAAGGCCGCAGAACCACTCAGCGAAGTGTCGGTCTACCGCTACCGGGGAAGTGTCTGGCGACGCTACGACAAGATGCGCCGGTTGCCGAACGGGCTCCTAGTGACAGGGGACGCGCTATGCAGCTTCAACCCCATCTATGGACAGGGTATGACTATGGCCGCGCTTGAAGCGGTTACGCTTCGCGATTGTCTATCCCACCCAAATGGTGACCTAGGCCGCCAGTTCTTCCGTGCAATGGCACAGCAGATAAGGCCAATTTGGGCGACCAACCAAATTAATGACCTCTACATGTCCGAGCCAGGCGGTGGGCGATCGACGCTGATGCGAGTATGGAACTGGAGCAACGATAAGGTGCTGACTGCGGCTGAGCGCGACCCCATCCTCACCGAAAGACTATTTCGCGCGACGAATCTCATCGACCCACCGACCCGCCTTCTCGACCCCTTCTTAATGAGCCGCGTCTGCTTAAATCTGTGGCGGCAAAGACAGTCACAACGAGCGACTTACGCCATCAATCACCGCTAGGACGCCACCATCTCCAGGTCCCAGGCCCCTTTTTTCACCCGGCCGGATGCTTTAATCCCTTCGGCCGCCCCCCGCGCCGGGCGACCTGCCTACTCGGATGCCTCAAGCTCTCCGTTTGCTGAAGTGCTGCTGCAACAGCACAAGTACGAACAGGCCGTCTCGATCTGGGCTCGCCTCGTCATTTGTTACCCGGAGACGCCGCAGGCAGTGCAGGCGAATTGCCCCGCAGCTTCCATCTTGATCGGATGCGACATCCCGCGTCGAAAGCCCAAGAGCACAGCGAAGAATTTGCGGGCAGCGGCTGCACTCAAGAAGCACGGAGCCTTGCGACTAACAGTCGGCGACTGCGCTTACCTACGGCCTGCTCGTCTTGAAGCGGCCTCGAAGTGAAGCCCCACGGGGAAATGTGTGGGACCTCACGCGCGTAACCAGCATAGCGGTCGCCGAAAACACGCTTCAGTCGCCGATCCTCCAATTCGTTGTAAACGATGCCATACCCAGCGTTCAACATTGCGATCGCAGCTGCCGTCATGGTAGGACCCGACAAAATTGCGCACGCCCATGAGAGCCCTATGCCTGACCAAAACAGCGGATGACGCACTCGAGCGTAAGGTCCACGCTGTATAGGAACAAAAGATACAGGATTGCAGAATTCACAAACGAAACCCACGCGCGCCGTTCCGAGGGTCCGCCAAGCCGACACGAATAATGCGAACGCCCCGATAGCCACCAAGATACCTAGTGCGTCTTCCGCAATGTCAAGAACCGACCTAGGAAGCTTAGGGAATGTTTCATTGCACGACATATTAATGCCGTTGAAGGATGGGCGCAACATCTGCGAAAATCCAATAGTGACTCCAGGAAAAATATCTACAATAAATGCCCGCCTGTATCCATCTCCATGCGAGAGGAATCGCTTGCGATGCCACTCAAAAATCACGCTATGCCAAAAAGTCCACAGCAGCCAGACGACCGTGACATTCAGCAACACCAACCACATCGATAACTCAAAAGCTGATTCAAAGACGGCCTGACAGCCGGCCACCCCTACCATTGCAAGTGGGAACCCAATCCAAATCGCGTAACGCATGAACTTTCGGTCAAATTCATCTTTGACTCGTAACGCATCGAGCAGATCGTCCACGGTGGACCCTCACGCACGTGATCGAAGGGCTAGGCCAACAGCCTGATCGCTGCGTCGATAACACGCACGCAGTGACAGCCAGGTGGGAGCTTAACATGCGACCGATGGCGCGTCATCAGTTTTGCCCAACAGGCACAGTCGATCCAAGCCGATGATCATCAAGCAGGTCAAATTGCACCGAACAACTTCGCGTTTAGGCGGCATGGGCGTGCACATCCCGAGGTAGCGTTGAAGCCAACGTGGCGCTCTACCCCGTGCAATCGCTGAAGCTGCTCGAGTGATTCGTGGTGTTGCTCATCCCACTGCCACTGCCCCATCACAGTGTAGGCAACCACTCAAGGAGGTTCCCTGAGGAACGTTGCGTCAGTGGCGAAGTGACCCTAGTTGCATCCAGCACGTGTACCCCGGCTGCTATGCGTATACCCGCCGGTCCCGACCTTAACGCTGCTAACAAGCTGGCTAAAATAGTCAGAAACAAAATTGACCAGAACGGAGGAGATATGGGACGCGAAGACACGAAACTAATCCAGTATCTTTCAATTTGGCTAGTGATAATTGCTCTGCTAAGTCATGCGGTAGGTTTTATTTTCTTAGCTCGCTTCCTGCCGCCGACACCGCCGTCACGCGACGCGTCGTATGTCGCATCTTTCTATCACGAAAATACCACCGGGATCATGGTTACGTGCGTGCTGGTGACGTTCGTCGGTCCCCTAATTATTCCATTCTTCGGCGTTATTTCCGTGCAGCTGAAACGAATCCAAAGAAATAACTCATCCTTAGCTTATACTCAGCTGATGAGTGGAGCAATCGGAGCCTCGATGTTTGCTCTCTCCGCCATGCTCTGGGCAGCCGCGGCCTTTCGGCCAGACCGCACAGCGCAAGAGATTCTGCTTCTTAGTGACATGGGCTGGATATTCTTTATGATGCCGGGCCCCTTCGCCATCACCCAGCTGGGTGCGATTGGTCTAGGGATCCTAATGGATCGAAGCCACGATCCGATTTACCCTCGCTGGTTGGGCTACCAGAACCTGGGTACAGCGCTGCTATTGGTGCCGACCGCCTGCGTTGCAATGTTCAGGACCGGCCCGTTCGCCTGGAATGGCCTCATCGCTTTCTGGGTTCCTGCTGCCCTCTTCCATATATGGTTTATAAGCATGCTGGTGTTCACCTTTAAGGCCATTCGCAAACCGCACGCCGCTGTTCTGGAACCGGAATCGTGATCTAGCACGCCACTCGAGCGGCTGCGATTACGAAGCCTTCAGATTGCCGTAACAACTATCCGAAGGACCGTATAGACAGGCGGTTTTTCGCTTACATAAGCACTGGTTCGCGCAATGGCTGCATCTAGCAACGACTCTTTGTCTCACTGGACCACGATCCTTACACCAGCCACGCATTCGCCGCGCCATCCATCTGACCAGCCCAGGGCCAATGAGCTCACGCATCCACTGACCCGTGGCAATCTGGACGAAATGTCGCACACCTATTTTCGGCTGGAGTCCTTTCTGACGGTTAGCGTGGCAGGCAACCCGCCCTCCACAGCGATCGAGAATTTTGGCGAATGGCGTGGCTGCCAACCAATCGGGAAGTTCACACAGTATCGCTGATGAATAATTGCGAGTAAGAACTGTGCGTTCATGTACCCAAGAGCCGACCCAATGCACCGATGTGGCCCGAATCCGAATGGTAAGAACGAAGTCGCCGGCCGCGATTGCACCTGAGCAGGGTTGGCGAAGCGGTTCGGATCATAACTGTCTGGGTTCTGCCACCACCGCGTATCACGATGCAGTGTGTACATTGGAACGCCGATTAACGTGCCCCGCGGGATGAAATAGCCGTCGATCCAGTCATCCCGCATGGCGAACCTAGGATTCATCGGGTGCCCTTGAAGGCGTTGTCCTTCGTCGAAACACGCCTTCGCCCACGTCAAGGACTGAAGATCATTGTACGTCGGTTGTCGTCCGTCCAGCGCATCGACCTCTTCATATAATTTGACGCGCGCCTCGCGGTTCCCATCGAGTAGCGCCAACGTCCATGACAGGGCCGCTACCACCGTTTCGTAGCCGCCGGCGATCAGCATCGCGGTCTCCTGGATCAAATCCTTTCGCCTGATCGCCGACCCATCATCGTATTGTGCATTGAGCAGGGTCTCGAATAGATCTTGACGCTCGATCGGGTGCCCAATACGGTAATCGATCTGCTGGGAAACCCACTTTCGCAAACGGAACCACGATTTGGGAAAGCTGTCAACTCCCGGAGCCGGGATTAAATTCGGTGGAGTACAGATGAAACACACCGCGGCAGCTGCACGCAGAACTGCATGCAGATCGACGTCAAGATCACATACCTCACGATCGGTCACTTTGATCGAAAACATCGCGCGCATGAAGGCGGGGAGGGTCACTTTTGCGATTTCGTATTGCAGATCAATTACCGCCCCCGTCTCGGCATAGATTTCCCACCTGTCGATGCGGCCGACGAACTCGTTGGCGATGCCGTCGGCCATCGTTGACAGGCTTCGGGCGCCGAAGAGCGGCGCAATCAACTTGCGCCGCTGTCGGAACACGTCGCCTTCCAACGTTGCTACTGAGGCGCCGATAACCTTGTTTAGACGCGCGCCAACGTTACCTCCCATGCTGTAAGCATTGCATGGATTATTCATCACATGCTTGACATGATCCGGGTGGCACACAAACACTGTCTCTCGCAAGGGAAATGGTAGCCGAAACACATCACCATATATTTGCTGACATTCTCGGACATACTCGAATGGATCTCGGAGAAACTCCGGCAATATCCCGACCCCGGGCCTTCCTCGTGGCCCTGGCGGGCGACGGTCTACGGGATGGCGAACACCACGAAAGAACCCGACCGGGTTCCTAGTAGGCCAGTACGGATCATCCGCTAGCGCCCTGACCATCGCCGTCCAATGGTCACGAGCTTTCCTCCCACGCCCACCTTGACTCATGCCACTACGATAGCTGCGACTCGCGCGGAACAGGTCTCGGCAGTTTTGCGGAGTTCTCCGACGTATCGGCTCAAGAAGGTGCTTGGCTGCACGAGGTTTCGAGCAACCCTAGGCGACGTGGACGTTTGACGTAAGCTGTGCGACAGTTGCCGACCGTTCCGCACGCTTGTGCGTTAGCATGATGAACGCCTGTAGGCAAAGCGCCACAGACTGGATCGACCACCTCGCCAGCGAGCACAGATACGAGCGCCATCCGACTGAAAGCGAAGAGCACGATGACCATTTGCCAGCATATCTCCCGAGAAGCAATGCTCCCTCTTAAGTTTTTATGTCTGGGGCACAATTGGAAGTAGGGAACGCCGAAGAAGTCCATTCCGACACCGATTTCGAGGTACTTATCGTCGGCGCGGGTTTTGGCGGTATCGGTGCGGCCATCGAGCTCATCAGGAAAGGCGTTGAGAACTTTTTGATTCTCGACAAAAACGATGGTGTCGGTGGAGTGTGGCGCGTCAACACTTATCCGGGTGTCGCAGCCGATCTGCCGTTCCTCTTGTATAGCTATTCCTACGCCCCGCCACGCAAGTGCACACGGTTCTTCCCGACGGGCGCCGAGGTTAGGGAATATATCGAGCAGATCGTAGATGATTATCGGCTCACCGATCGAATCCTACTTAATACAAACGTTGCGGAAGCTGTTTGGGAAGAGCGTTCGCACAAGTGGACAGTACATCTCGCTTCCGGCGAGACCCTCGTTAGCCGGTTCCTGATCTGTGGAATAGGTCCCTTTTCGACGGCCAAGATGCCTGACATTCCAGGTATCGAGGACTATCAGGGTAAGGTAATCCACACTGCCCAATGGGATCACGACTTCAATTATAGTGGAAATCGTATTGCTGTTATTGGCAATGGCGCAAGTGGTCTTCAGTTGATACCCGAGCTTGCCGATATTGCTACAAGCCTAGTTGTGTTTCAGCGCCGCCCGACCTGGGTGGCACCTAAACCCGACTTTGCAGTCCCGCAGTTTATGTCGTCGCTGGTACGGCACGCGCCTCTAACGCGAGTATTCATGCGCGCTGTCATCGCGGGGATGGTCGATCTGCTGATTACAGGACTGAGCGTCTTCCACAAGCGAGTACCCTTTATGATTCCGCTGATGCAGCGCATCGGCTCACAAGCCTACTTCCTTTCGGTGCGAGACCGTGAGCTAAGTAAGCGCCTAACGCCGGAATATGCACCGTATTGCAAGGCTGTCTCCATCTCGAACCGTTACTTGCGCACCTTCACACGCGACCACGTAGAACTGGTCACTGTTCCGATCGAGAAGCTAACTGCCAGGGATGTCGTCACCAGGGATGGCACGCTTTATGAAGTTGACGTTTTAGTGTGTGCTACAGGATTCAAGGTTATGGATGATGGCGCGATCCCATCATTTCCCACACGAGGGCGTAACAACACAGACTTACATCGCTTTTGGCAAGAGCATCGCTTTCAAGCGTACCAAGGCGTCTCTGTCCCGAATTTCCCCAATCTGTTCCTAATAACTGGGCCATATGCCTATCCTGGCGGGTCTTGGATCACCATGATCGAATGCACCAGCAAGCACGCTGCGCGGGCAATTGCTGCCGCACGGGCGCGCGGGGCCACTGCAGTCGAGATACGGAGCGGACCTCATGACCGATACTGGCGCAAATGCCTACGGCGAGCGAGGGATACGATTTGGCTATCAAAGCGCTGTGCAGGATCGAATTCCTACGTCGTTGACAATCATGGCGATCCCGTTCTTATCCGGCCGAGCTTGCATTGCGAGATGTGGTGGGGAAACAAGCGGTTCCCCCTCGGCCACTATGCATACAGCACTACGCCAGCAAGTTGTTAAAGAAGCAACCGGTGCTGTCCGATGCAGTGCCATTGCCGCGATTTTCTTATTCAGCGAAACAAGACCTCCACCTAGACAATCGGGTGGCAAATGACGATGGTGACCGAGCGACATTATTTCTGATTTCCGTCAAGGACATTTGGGACGTTGGGTCTGCTGCACGGATAAGTGACACCGAGCTCGCTTGCCCAGACTGGGTGGGCTGAGAGGATGTCATCATGGCACGGCCGTATCCCCAGGAGTTCCGCGACGATGTTGTGCGGGTTGCCCGCAATCGTGAGAACGGTGTGACGATCGAGCAGATTGCCGCCGATTTCGGGGTGCATCCGATCACGCTGTCGAAGTGGATGCGCCAGGCCGATGTCGATGATGGGGCTAAGCCGGGCACGACGACGAATGAGTCGGCGGAGTTGCGGGAGGCCCGGCGGCGGATCAAGCTGCTCGAGCAGGAGAACGAGGTGCTGCGTCGGGCCGCGGCATATTTGTCGCAGTCGAACCTGCCGGGAAAAGGATTTACCCGCTCGTGAAAGAGCTCGCCGCCAACGGGATTCCGGTGGTGGTGACGTGCCGGGTCCTCAAGCTCGCCCGCCAGCCCTACTATCGCTGGCTGACCGATCCGGTCACCGACGCCGAATACGTTGCAGCGCAGCGGGCCAACGCGTTGTTCGACGCCCACCGCGACGACCCGGAGTTCGGTTATCGGTTCCTGGTCGAGGAGGCCCGAGACGCCGGCCACCCGATGGCCGAGCGCACCGCCTGGCGGATCTGCTCGGGCAACGGCTGGTGGAGTGCCTTCGGTAAGCGCAAGCGGGGTAAGAACGGCAAGGTTGGCCCGCCGGTTCACGATGATCTGGTCGGTCGTCGTTTCACCGCTGACGCGCCAAATCGATTGTGGCTAGCCGATATCACCGAACATCGCACCGGTGAGGGCAAGCTCTATGTGTGTGCGATCAAGGATGTGTTCTCCAACCGCATCGTCGGCTACTCGATTGACTCGCGGATGAAGTCACGGCTGGCCACCCAAGCGTTGGCCAGCGCGGTCGCTCGTCGTGGCGATGTTGCCGGCTGCATCGTCCACAGCGATTATGCCGAGGTCTGTGTTAAGCCGAGGATCTGCGGAGATGTCCTGCGCTCGTGGGGGGTGCTGGCGGATTTCTCGGCTTAACGTTTCGGGTGGTGGTTAGCGTCCGTCGTATCTCTACGTCTGTGGAAGGAGACGGTGATGGATACGACGGTCAGTGGGATCGGCGCGGTTGTCGTGGCGGAGTTGCGGGCGGCCGGCTATATGGAATCGACGGTTGGTCAGTACGCCAAGACGATCAAGGCGCTGACTGAGTTTGCCTCGGGGCGTGAGTATTCCACCGGCTTGGGTGTGGAGTTCGCCTCGATGACGACCAGTGTACGCACCGGCCGGTTCAGCGCGCAGCGCCGGTTCGATTACCGGCGTCTTGTTACGGTGTTCGACTCCTATGTGCAGACCGGGCGGGTGGACCTGGCGGTTCGTGGCCGCGGCGGCGGAGGCCCACGGCCGGTGGGCGGCGACTTCGTTGCGCTGGACGCCACGTGGGAGGCCGAGATGGGCCGGCGCGGTCTGGCACCGGCCACCCGCGAGGCCTATGGAAGGGTGGCGCGAAGCTACCTGGTGTTCGTAGAAAGACGCGGGATCGCCGTGCTGGACGGCGCGGATGGTGCCAGTGTCTTGGCGTTTTTGGAATCCATACTGGATCGGTGGGCCAGGTCATCGCTGTTTTGGGTGGTGTCGAACTTTCGTCCGTTCCTGAAGTTCACCGGCCGCGCCGATCTGGTTAATGCGCTGAATCTGGCTGGCGTCAAACGCTTTCACGCGATAGTCCCCCTCTTGGGCGACGCCGATGAAGAGCTGGTTGTTCGTGCGTGTGCGTCGGGGGTGGTCAGCGCGCGAGACGCCGCGATCACTTTGCTCGCATTGACGACGGGATTGCGGGCCTGTGACATCGTGGCGCTGCGGATCGGTGATGTCGACTGGCGTGGGCACACGATCGGGATCGTGCAGCAGAAGACGGGCAACCCGCTGACGCTGCCGTTGCCGGCGCTGCTGCTGGGCAAGCTGGCTTCTTATGTGCTCGACGAGCGTCCCAGCTCCGGCGATGATCACCTATTCCTGCGTATGAAAGCGCCACACACCCGGCTCAACGACCACGCGACGGTGCACCGGGTGACCGTCGAGACATTCCGGAAAGCGGGGGTGGCCGAGGCGAAGGCGGGAACCCGGTTGCTGCGCCACAACGCCGCATCCCGGCTGCTGGCCGCAGCGGTTCCACTGCCGACGATCGCGGCAGTGCTGGGCCACGCCAGCGAAGAATCGACGAACCTCTACATGAGCGTCGACCGGCGACGTCTGCTCGATTGCGTTCTGCCGGTCCCAGAAGCTGTGCGGTCATGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP009483|515358:592647|578519_580463_-|WP_023364740.1|integrase|DBSCAN-SWA
MTVATVQDSIDAGTLLSDYLDHVARLRLSDRAIRDRIRTAREFLARHPDLAAWMALPAVERAGELRSSGAWPLLCYAIGAGRLRLDVELAVIKQLTGLGAAVEMRDSAGFSAMREAGNRLGWSSSWIETVLGECLAVLVACHGGLVADLTEQAIDEFDSALSASSIPRSSRRAYRARLASLRQLLYEVRVLDAAPRRRPWARSLEQRFTDVAMAAPILDTLLRYIRVRAAVLRPKSVESLINDLLPFVEYLTAHHSKLTSLRELDRACIEDYLTWNRTRGWRGQRAAAGAGRTVSAAVAQSAVLSLRNLLDDITAWGWEEAPPRRLVFAADVPKLDQPLPRALAPDIDAAVMNAVARLDDSFARIGLTVLRGAGLRVGELLDLELGSIIDYGAAGTWLKVPLGKLATERMVPLSAATTAALDEWVTHRDAHRPLAHPRTGVLTDFLFTQYGRRLGYTRLRNGLLAAAQSSGLRGPDGGILVVTPHQLRHTWATELANAGMSMQALMALLGHVTPQMTIRYATLASPTLRAAYDDAMGKMRRQFTLTPVGRPILPDKVSWLHSEMLKTRVGHGYCARHPTAGACPYANICETCDNYITAPEFRGALTNQLADVQALKSDAENRGWTDEAARHDRVAHALTDHLQRLDR
>NZ_CP009483|515358:592647|571207_572650_-|WP_042311693.1|DBSCAN-SWA
MASNNKNSNNSGANNDDWIIDPIFSLCKALGYLLWWAVLFPAVSIPIIASAATAITHGPRPGLIIGIAFAATYAGWAWLDPRSFRDWVTEPVRRRWLTWWRYTRTWESVCALHGLNARLGERSLVPTLRSARIGKTTDVLHLRVVTGQSLTDWHKQSEALAAAWHADRITIRATGPGELRITLMRHDVLADPIALPMPTAATPVDVGSVRVGMTETRHWWHLPLLGHHVLVAGATGAGKGSVLWSLIAGIAPAVKTGQVRLCVIDPKGGMELGAGAPMFTVFTHDATDTTLQLLRQLVKVMHARANRLRGQTRLHTPTMAEPLFVVVIDEIAALTAYVTDRKVRTEIEQLLGLLLSQGRAVGISVVAAVQDPAKDTLPVRQLFTARIGLRLTEASQTTMVLGQGARDAGAECDHIPDTTPGVGYMMIDGTAEPVRARAFHVTDHDIITLARIFRPPISHRGGDQGRNTGSGPTSGGASGA
>NZ_CP009483|515358:592647|519683_520169_-|WP_036395983.1|DBSCAN-SWA
MTHVLVLVLALLIGVVAGLRSVTAPAAVSWAGYLGWFPTLQHTWASWVGNIVTVVTLSALAVAELVNDKLPKTPPRTAAPVFAVRIILGGFAGAVIGTAWGYKFGGLGAGVVGAVLGTLGGYHARRRLVAASGGRDLPIALLEDSVAVLGGFAVVASAAAL
>NZ_CP009483|515358:592647|584544_585381_-|WP_080673988.1|DBSCAN-SWA
MDDLLDALRVKDEFDRKFMRYAIWIGFPLAMVGVAGCQAVFESAFELSMWLVLLNVTVVWLLWTFWHSVIFEWHRKRFLSHGDGYRRAFIVDIFPGVTIGFSQMLRPSFNGINMSCNETFPKLPRSVLDIAEDALGILVAIGAFALFVSAWRTLGTARVGFVCEFCNPVSFVPIQRGPYARVRHPLFWSGIGLSWACAILSGPTMTAAAIAMLNAGYGIVYNELEDRRLKRVFGDRYAGYAREVPHISPWGFTSRPLQDEQAVGKRSRRLLVARLRAS
>NZ_CP009483|515358:592647|583127_583367_-|WP_036393171.1|DBSCAN-SWA
MNAGVAVSNSRADDAVRLTYNWLNGVMAINDLNVTDGANPASEVGFQERAAGKVNDNRGRVGKFTRPIELMPPDPYGHT
>NZ_CP009483|515358:592647|517140_517944_+|WP_023364697.1|DBSCAN-SWA
MNGCFYRRLGDDGDYQVFDSTDYTRSNWNPEIQHGSPPLALLTKLIEELSAGSSLRIGRLNLDILGAIPVAPVRARAWVERPGSRVCLMVAELHADREGGPARAVARVTAWLLAVGDTADVESARYPAVVEGPAEPLPAVFADAGGYFDAISWRPQQSAGHSGAVSWFTPIAHIVDTDPTTALQRLAVVVDCANGVGAVLDPNQFVFMNTDTVVHLHRLPTGDDFALRARASVGPDGVGVTTAEVYDKAGFIGTSAQTLLVQRRARS
>NZ_CP009483|515358:592647|524248_526603_+|WP_023364704.1|DBSCAN-SWA
MAITEYRPGTTFPGVIGRTADESTPAWPALKRPAEGAPNVVFIVLDDTGYGHLGCFGSPISTPNIDALAADGLRYSNMHTTALCSPSRSCILNGRNHHSNHLACLTNGSTGFPGSDGYIPFENGFLSEILRAQGYNTYCVGKWHLAPEETMTAAGPYDRWPLGRGFERYYGFLGGDTHQYYPDLVRDNSQTEPEATPEQGYHLTPDLVNKAKAMIADAKQVAPDKPFFLYFAPGATHSPHHVPKQWADRYAGKFDAGWEAYRQRVFTRQRELGLLPATAELSAPDPDVADWETLPADERRLYARMMEVFAGFLEHTDHYIGELVQFLKDLHEYDNTVIMLVSDNGASAEGGPTGSVTEVRFFNNVADTVEEGLARIDEIGGPTVFNHFPWGWTHAGNTPFRRWKRETYRGGSSDPLIVTWPRGIAARGEVRSQYAHLIDMVPTVLEALRIDPPTSIGGVTQSPIEGVSFAHTFDDAAAPTRHLTQYFEMLGHRSIYHDGWRAVCPWPGTSFAESTHKFGDVITAEMLSQLDESGWELYHVAQDPAETTNLAGQERARLIAMITLWYSEAGRYNVLPIDSRGLARAFVERPQIAGANRTRYVLYPGTQAIPAAAAPKILNRPYSINAEVELTEESSGVLLSMGGNDGGITLYVKDGQLCYAHNYVAKEIFTIRSEQRVPPGRHFLSVEFTPTGPVDLKNGRGTPGDVTLFVDGAAVGRGEFPVTTPLRLAQGGAMLVGANTGSSVTPDYDPPFAFDGRIHRVIVDVSGEHVEDYQAQMKIALTKQ
>NZ_CP009483|515358:592647|581565_582627_-|WP_023364744.1|transposase|DBSCAN-SWA
MTAAHDIDLPAVLAERLTTTHPDVLRELLATFIHTLMGAEADALCGAGYGQRSSERTNSRNGYRHRQFDTRAGSLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLLGVSTRRMDKLVETLGITGLSKSQVSVMAKELDTAVEAFRTRPLDAGPYTFMAADALVLKVREAGRVVNVHALIAVGVNAEGYREILGIDVSTAEDGAGWLTFLRSLTARGLSGVALVTSDAHAGLLSAIGATLPGASWQRCRTHYATNLMAITPKSSWPWVKTLLHSVFDQPDATSVAAQYDRIIDALADKLPKVADHLEAARSDLLAFTAFPKQIWRQIWSNNPLSVNRPSGDTNLTAA
>NZ_CP009483|515358:592647|567881_569528_-|WP_023364729.1|DBSCAN-SWA
MSLRFAFYGRVSTEDAQDPEASRSWQKRRAIDLIAPHGGVLAADYFDVGQSRSLPWKRRPEASRLLADVACPDHNFDAVVIGEPARAFYGPQFALTFPILTHYGVGLWVPEVGGAVDPGSEAHDLVMTLFGGMSKGERARIQVRVRTAMSALAQDTSRYLGGRPPYGYRLVDAGPHPNPAKANLGQRLHRLEPDPATSPVIERIYRMYADGAGLRYIAQQLTDDGVPSPSQYDPARNRHRDPRGWSHSAIRAILDNPAYRGIRVWGKQEKYEVLVSPDDVAAGYETRMRWRDQADWIAPDRRTHEALIPDELVEAVRRRTQARRGPGLVCSRESTVPYALRGLLFCAACGRRMQGAARVGKRTTRILYRCELGKSRSIPVDLSDHPRTVYLREDEVTARLDEWIATLADPEDLARGQDVDPVAGTGYAALQRQLREVNAKIAALVTAVESGVAVEDLTAALRRRTAERDELKARLEQAERPRVMSAAQMSELVEELGGLSAVLGAATGAERAEVYASLGLRLDYDPQLREVKATADLSRVAGRVRGGT
>NZ_CP009483|515358:592647|532815_533994_-|WP_080674189.1|DBSCAN-SWA
MAICGAGTAGLSLAERLSALGAEVVVLERSSGPRTHGHMIDFYGAGYDAAEAIGVLPAIQRVGYPLGDSSLIDRHGRRRAALPYRQIARALDGRLCRVMRPDLEKVLLDNLPPQVELRFGATVSDVAQRDDRVTVTLQRGAQLDADLLVGADGIHSTVRTLVFGVEPQYLRYPGFRSASFVLDAPGVRGSAAEHVVFTDTADRQLGLHLLRDGRTAVTAVYRTVDASPPHDVRAALREEYAGMGGLVAEVLDRCPEDGAVEYDQVAQIQMPRWSSKRVVLIGDASFAVSALSRQGASLAVASAYVLSEQLRKTSSVERALAFYERLWRPVVEDKQQSGQAASGWLWPGPSQSAIRRAMLRLSWRPLVNRFIEATLAGEPTALITMLRLGSGD
>NZ_CP009483|515358:592647|537899_538715_-|WP_023364712.1|DBSCAN-SWA
MNPSNDECEVLRHGELTVLGRIRSASNATFLCESTLGGKTVHCVYKPVAGEQPLWDFPDGTLAGRELSAYLVSASLGWNIVPYTVIRDGPAGPGMLQLWVRQPGDSLDAEARPGPDLVDLFPTGKARPGYLPVLRAYDYAGDEVVLMHADDDQLRRMAVFDVLVNNADRKGGHILCGIDGRVYGVDHGVCMHVQDKLRTVLWGWAGKPIDEPTLEPIARLADDLRGSLADELRDHVTSAEIAALRRRVRALLDNPVMPGPNRHRPIPWPAF
>NZ_CP009483|515358:592647|520294_521149_-|WP_036393190.1|DBSCAN-SWA
MLRVAVPNKGALSEPATEILAEAGYRRRTDPKDLTVIDPANNVEFFFLRPKDIAIYVGSGQLDFGITGRDLVCDSDAPVRERLALGFGSSSFRYAGPAGRDWTTADLAGKRIATAYPNLVRKDLAAKGIEATVIRLDGAVEISVQLGVADAIADVVGSGRTLSLHNLVAFGEPLCDSEAVLIEGADRDGAEHSEARDQLVARVQGVVFGQQYLMLDYDCPRAVLHQATTITPGLESPTIAPLADPEWVAVRALVPRRGVNGVMDQLAAIGAKAILASDIRFCRF
>NZ_CP009483|515358:592647|515358_516201_-|WP_023364695.1|tRNA|DBSCAN-SWA
MSATGPFAAGERVQLTDAKGRHYTMVLTPGNEFHTHRGSIAHDAVIGLQQGSVVKSSNGAPFLVLRPLLVDYVMSMPRGPQVIYPKDAAQIVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPEGRVISYEQRADHAEHACRNVTNFYGAAPQNWRLIVGDVADSDLPDGSVDRAVLDMLAPWEVLDSVSRLVSAGGVLVIYVATVTQLSTVVEALRAQQRWTEPRSWETLQRGWNVVGLAVRPQHAMRGHTAFLVTARRLAPGAVAPAPLGRKRPGRDG
>NZ_CP009483|515358:592647|590443_590752_+|WP_023364752.1|transposase|DBSCAN-SWA
MARPYPQEFRDDVVRVARNRENGVTIEQIAADFGVHPITLSKWMRQADVDDGAKPGTTTNESAELREARRRIKLLEQENEVLRRAAAYLSQSNLPGKGFTRS
>NZ_CP009483|515358:592647|534022_534916_-|WP_023364709.1|DBSCAN-SWA
MTSVQDKVVFITGGARGIGAEVARRLHNKGAKLVLTDIGTAELTTIAAELGGDGRVLTVVADVRDLSAMQAAADLAIEKFGGIDVVIANAGIASYGSVLQVDPEAFKRVLDVNVLGVFHTVRATLPAVIERRGYVLIVSSLAAFAASPGLAPYNATKAGVEIFANALRLEVAHHGVSVGSAHMSWIDTALVRDTKADLPAFDELLRRLPWPLNLTTSVNKCAAAFVKGIEGRKTRIFCPRWVGLFRWLKPVLSTSVGERPIRKITAELLPRMDAEAAALGRSTSAYTHALDNASEKQ
>NZ_CP009483|515358:592647|526701_527949_-|WP_042313221.1|DBSCAN-SWA
MSAPVWMAFPPEVHSALLSAGPGPASLIAAAQAWSSLSAEYGAVADELAPVVAALRTEAWRGTAAECCVAAYVPYLAWVMQESADCAQVAAVHEITAAAYQAALAAMPTLGELAANHATHAVLLATNFFGVNAIPIAFNEADYARMWMQAATIMNVYETTSSPAVASTPHTPPAPAIIKPGAGLVNAIETTITPFPIWQILQILLDAVVGVLHCIRESLVATVLALLFIPLCVLLAVIALLTGHVAMAEQFLGFIVNLAIIPFQFFLEAGWIFIVGLADICELVIAWFLGNLGFVGGPGLVTQLATTTALSGGAALGVGALKGTTVALELAPASFAAMAVGADGSLATAGSAVSPAELGGPVGFAGTITNGTVPQAGGLTTLSGHTCCDGVQVPMLPSGWAQHVCGDDSTSWVLG
>NZ_CP009483|515358:592647|580459_581494_-|WP_036393475.1|integrase|DBSCAN-SWA
MRVQRVDEGYRLGGDWEGLDSANAFLTHLAGRGFSAATVRAYAFDVANLARFLTERDVTLSEVQAPLVFDWIDWQGVRRTGRPQPGSAAASTVNRRVAAVRALFEYLAMTGRRGNNPVPSPRRGQGLRRSERGLLGHLGPGRARPGGRLVRQPQLLPESLPASDIDAFVATLGSHRDRAMVLAMLLGGLRSAEARGLLLADVDMGRRRLRVIGKGGKERYVPVDAAFFTEVAAYLRLERPAGLSTPQCFVVLRGPTTGAPVSEAGLRSLFRRHRELSGSIRVRPHRLRHTYGTELASAGIDLLALRALMGHASPETTARYVHLSLEQLAAEYGAARASLAGARR
>NZ_CP009483|515358:592647|574439_575180_+|WP_042311696.1|DBSCAN-SWA
MTRDIIPDLTTTAPAATSKIAVLPVGAFEQHGPYLPLGTDTLIACAVTTAITKHHRVLQLPPVTFGCSHEHAAYPGTVSIGAATLTAIVTDITQSLTHQQIRGLIVVNAHGGNAVLTNVVQHANQSAHQLKLGLYPSREDWAEARTAAGVTSSNHDDMHAGELETSILLAAHPDYLRDGWASSDHSATDRRYLTTLGIGPYTPTGVIGYPSQATAAKGRAALDHLGRNVATLIDLLAPPPQPEPTP
>NZ_CP009483|515358:592647|549520_549979_+|WP_080673987.1|DBSCAN-SWA
MDFAGLPPEHNSARMFAGAGSAPMLATAAAWQGLAAELGSSAFAFASQTSALCHPASARHAAHSFTARGAAFTDCAAAARGTAQDTTCSAAAAASAHARGTARAASASITPEADLTTSATACAAVASVAARAAAASVAADPSGTANASTAGE
>NZ_CP009483|515358:592647|563746_564394_-|WP_023364724.1|DBSCAN-SWA
MADSADRVTVVVADDHPVMRQGVVRALKSSGRVEVVAQVADGRAALDAIRQLRPAVALLDYKMPELDGLEVTHAIARDRLPTRVVLLSAFDDSPVVYKALAEGASGFLTKESDSDEIVNAVVRCAEGASYLPAGIAGGLAGEVTRRGRGATTLLTEREAQVITMMADGLSVPQIASRLHLARSTIKTHVHSLYEKLGVSDRGAAVAEAMRRRLLE
>NZ_CP009483|515358:592647|531964_532819_+|WP_042313224.1|DBSCAN-SWA
MLPELHNTVVVAAFEGWNDAGDAASDAVSHLADIWDARPIVEIDDEAYYDYQVNRPVIRQVDGVTRELEWPAMRISHCRPPGSDRDVVLMHGVEPNMRWRTFCAELLAIVDKLNVDTVVILGALLADTPHTRPVPVSGAAYSPESAQIFGLQETRYEGPTGIAGVFQYACVAAGIPAVTFWAAVPHYVSHPPNPKATVALLRRVEDVLDVEVPLGDLPTQAEAWAQEISEMAAEDDELAEYVQSLEQHGDAAVDVNDVLGTIDGDALAAEFERYLRRRRPGFGR
>NZ_CP009483|515358:592647|516274_517144_+|WP_023364696.1|DBSCAN-SWA
MADQLIPEADLRIRPALSPSRATDFKQCPLLYRFRAIDRLPEAPSAPQLRGSVVHAALEQLYALPAVQRGPETARSLVEAAWEQVIAGEPALADELQPQALLDEARALLSGYYRLEDPTRFDPQCCEHRVEVELADGTLLRGYIDRIDVAATGELRVVDYKTGKAPPAARALAEFKALFQMKFYGVALFRSRGVLPTRLRLIYLADSQVLDYSPDRDELLRFEKTLMAIWRAIQSAGRSGDFRPNPSRLCDWCPHQAHCPAFGGTPPPYPGWPNYAGADTVVRPTEPAA
>NZ_CP009483|515358:592647|585881_586601_+|WP_023364748.1|DBSCAN-SWA
MGREDTKLIQYLSIWLVIIALLSHAVGFIFLARFLPPTPPSRDASYVASFYHENTTGIMVTCVLVTFVGPLIIPFFGVISVQLKRIQRNNSSLAYTQLMSGAIGASMFALSAMLWAAAAFRPDRTAQEILLLSDMGWIFFMMPGPFAITQLGAIGLGILMDRSHDPIYPRWLGYQNLGTALLLVPTACVAMFRTGPFAWNGLIAFWVPAALFHIWFISMLVFTFKAIRKPHAAVLEPES
>NZ_CP009483|515358:592647|572738_573074_-|WP_041327080.1|DBSCAN-SWA
MRLRIDTSGTRFIVTRAAEPRLNFETGSPKVDTATGVPLFATQVLALDDTGGEVLNVTVAGDPKVTVTQPVSVSGLVAIPWAQGDRSGVAFRADAITPTAASSDQASRTQK
>NZ_CP009483|515358:592647|575816_577211_-|WP_023364735.1|DBSCAN-SWA
MTIPDRLQRVLRLPTPVASLRTIVIVAALSVVAVVIFLGAWVWVGITNNQYSQLDRQLDSLSTLGDVSALGGTHQGNVDEPMPDGMVRTVRSGGITVSKPSNVTLPEFGNGYTTATVNGIPYRVHTFITGGASIAIGAPITEARQAIKQLHLRVLLICGGFVVGTFLVGSWMWSIMIKPFRLLAQHARAINAQSSPEEVQVDGVWEAVEIAEAVEGMLARIGTEQQRTKAALESARDFAAVASHELRTPLTAMRTNLEVLHTLDLPPEQRKEITEDTMRTQSRIEATLTALERLAQGELSTSDDHVPLDITELLDRAAHDAVRVYPDLNVTLRPSPAVLMLGLPTGLRLVIDNAVANAVKHGQATQVQLSAITSRHGVEIVIDDNGTGIPEGERTAMFERFTRGSKTSHSGSGLGLALVAQQAELHGGTASLEDSPFGGTRLVLRLPGPQPYEGTKMEYGFKRL
>NZ_CP009483|515358:592647|539348_540077_-|WP_023364714.1|DBSCAN-SWA
MTVILLRHGRSTSNTAGILAGRSEGVGLDDKGREQATGLIDRFGDLPVRAVVASPLLRCRATVEPLADALCLEPLVDDRLAEVDYGDWTGRKIAELTNEPLWRVVQAHPSAAVFPGGEGLAQVQARAVTAVREHDRRLALEYGGDVLWLACTHGDVIKAVIADAYGMHLDSFQRITADPASASVIRYTELRPFVLHVNHTGARLSAGLRAAPPPKAEPGGEQPAAPDAEVPSGDAVVGGSTD
>NZ_CP009483|515358:592647|541390_542440_+|WP_036393495.1|DBSCAN-SWA
MLTATKQAVQRCLCAAAALLTLVTACSSNPLHTAPPTIQPAQPAVSPPVSQAPAGVIRPLSGHPQAALYDNGARRLVVLTPDADPSAPSGITVFDDAQTPSRVITLPGPATALTCDDHGTAYLAARGGYLVVDLSAGRIAQVSVADAAGTDFTAIARRADGKLVLGSADGAVYILDSESSGTARTANRIKIFARVDSLVTQGNTTVVLDRGQTSVTTIGADGRARQALRAGEGATTLAADPLGRVLVADTRGGQLLVYGVDPLILRQAYPVPQAPYGLAGSRELAWVSQTASNVVIGYDLSTGIPVEKVRYPTVQQPNSLAFDDASGTLYVVSGSGAGVQVIEHAAGIA
>NZ_CP009483|515358:592647|566333_567686_-|WP_036393176.1|DBSCAN-SWA
MVGKVTVTGVGDDVAEVVSRLIRFDTTNTGEPETTKGEAECAHWVAEQLAEAGYQPEYVESGAPGRGNVFARLAGAKGQAGSRGALLIHGHLDVVPAEPADWSVHPFSGAIEDGYVWGRGAVDMKDMIGMMIVVARHFRRAGIVPPRDLVFAFVADEEHGGKYGAQWLVDNRPDLFDGVSEAIGEVGGFSLTVPSRDGGDRRLYLIETAEKGIQWMRLTARGRAGHGSMVHDHNAVTAVAEAVARLGRHQFPLVCTDTVAEFLAAVSEETGLTFDTNSPDLDGAIDKLGPMARMLKAVLHDTANPTMLKAGYKANVVPATAEAVVDCRVLPGRQAAFEAEVDELIGPDVTREWIRDLPSYETSFDGDLVDAMNAAVLAVDPDARIVPYMLSGGTDAKAFARLGIRCFGFSPLRLPPDLDFTSLFHGVDERVPVDALKFGTEVLTHFLTHC
>NZ_CP009483|515358:592647|534940_536185_-|WP_023364710.1|DBSCAN-SWA
MRSWSSAPVPNLPGRGPELRLYDTADRQVRPVTPGPKATMYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHDVQYVQNVTDVDDPLFERADRDGVDWRELADREVKLFRADMEALRVLPPHDYVAATEAVAEMVELIEKMLASGAAYTVDPEIGDYPDIYYRADATVQFGYESGCDRDTMLTLFEQRGGDPSRPGKTDQLDALLWRAARAGEPSWPSPFGPGRPGWHVECAAIALSRINSGLDIQGGGSDLIFPHHEFTAAHAECVTGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSTLRAQGVEPSAVRLGLLAGHYREDRFWTHQVLDEAAGRLQRWRTATALPAGPDAADVIARVRRYLADDLDTPKAIAALDGWATDALEYGGHDESAPTSVATAIDALLGVDL
>NZ_CP009483|515358:592647|522741_524229_+|WP_036393185.1|DBSCAN-SWA
MAAETADAAARPNILVIWGDDVGMWNISAYHRGMMGGSTPNIDRIANEGMIFMDHYAQASCTAGRAAFITGQYPIRVGLSTVGLPGSDIGLQKEDPTLAEMVKPLGYTTGQFGKNHLGDRDEHLPTLHGFDEFFGILYHLNAGEYAEQYDFPTNPEIVEKFGFGQRGALHCWANPDGTQRIEDTGPYGRERQRTLDREFLTETKRFIRDAAAAETPFFVWHNSTRMHYRTNLAPEYDGKSGYGVYADGMMELDDHVGELLDLLDELGIADNTLVMWSTDNGAACNSWPDGGNHPFAREKGVGGYEGAFRVPALVRWPGVIPAGVASGEFMAMEDWIPTIMSMLGQPDLADSLKKGATIGGREYRVHLDGVDQTDLLTGRGKSKRMEFYYFTETSLHGLRYGDWKVLLKTQDRWFNGIQQKLTTPLITNLKLDPFERFHKARGFDEWQENHAWLYGPAALQVMRFLATLHEFPPRMRSFGIDVDELLNQLNPARHR
>NZ_CP009483|515358:592647|565080_565722_-|WP_023364726.1|DBSCAN-SWA
MTHVPPHRRAARACVLVLPGGKVRSDGASRWWQLANLRMMFLTRALRRRLGRDVHVRRVQYRVRGWNSPRLDAVRDGLAALDDVRQRLAPQHVVLVGHSMGGRVAAQLSGRGDVGAVVALAPWWIGGDGDVIPARTRLLVLHGTADTWTDPGSSCTQATRARRRGVDAQWVGIHGAGHYMVRYWSEWHWRTTDFVADYLSDGRRYSPGKQNGK
>NZ_CP009483|515358:592647|577207_577912_-|WP_036393174.1|DBSCAN-SWA
MDDEPTPSLLVVADDEDVLTSLERGLRLSGFDMTSAKTGPDALGVLAEARPQAVVVDIDQPTLRGVSVVSAVRSVDNRIPVCVLSGRSAISDRVPGLAEGADDFMYKPYRLSELVTRVRGLLCPPVLVTNFSTETISVGPLMVETGRRRASINGIEIQLTRREFDLLAVLAQHATEILSRARLLELVWGNSHFAADTRVVDAFIDSVRSKLDLVCGPRLLHTVPSAGFVLRVQQ
>NZ_CP009483|515358:592647|590748_591390_+|WP_023364754.1|transposase|DBSCAN-SWA
MKELAANGIPVVVTCRVLKLARQPYYRWLTDPVTDAEYVAAQRANALFDAHRDDPEFGYRFLVEEARDAGHPMAERTAWRICSGNGWWSAFGKRKRGKNGKVGPPVHDDLVGRRFTADAPNRLWLADITEHRTGEGKLYVCAIKDVFSNRIVGYSIDSRMKSRLATQALASAVARRGDVAGCIVHSDYAEVCVKPRICGDVLRSWGVLADFSA
>NZ_CP009483|515358:592647|586864_588301_-|WP_080673989.1|DBSCAN-SWA
MVRALADDPYWPTRNPVGFFRGVRHPVDRRPPGPRGRPGVGILPEFLRDPFEYVRECQQIYGDVFRLPFPLRETVFVCHPDHVKHVMNNPCNAYSMGGNVGARLNKVIGASVATLEGDVFRQRRKLIAPLFGARSLSTMADGIANEFVGRIDRWEIYAETGAVIDLQYEIAKVTLPAFMRAMFSIKVTDREVCDLDVDLHAVLRAAAAVCFICTPPNLIPAPGVDSFPKSWFRLRKWVSQQIDYRIGHPIERQDLFETLLNAQYDDGSAIRRKDLIQETAMLIAGGYETVVAALSWTLALLDGNREARVKLYEEVDALDGRQPTYNDLQSLTWAKACFDEGQRLQGHPMNPRFAMRDDWIDGYFIPRGTLIGVPMYTLHRDTRWWQNPDSYDPNRFANPAQVQSRPATSFLPFGFGPHRCIGSALGYMNAQFLLAIIHQRYCVNFPIGWQPRHSPKFSIAVEGGLPATLTVRKDSSRK
>NZ_CP009483|515358:592647|518307_519687_-|WP_023364698.1|DBSCAN-SWA
MTQRFDSIIVGAGQAGPSLASRLTGAGQRVAVVERKLIGGTCVNNGCIPTKTLVASAHAAHVARRAAEYGVGTGSVSVDMAKVKARKDGVMLNDRKAVEDWLEGMDGCTVVRGHARFEDPHTLRVGDQLLQADQIFLNVGGRAVAPNIPGLSDVDYLTNVSILELDTLPQHLVIVGGSYIALEFAQMYRRFGAQVTVVERGPRLASREDEDVSASIREILEAEGIDVVVNADDVRLAKRDNGFGGFELTPSVGAPAIAGSHLLLAVGRRPNTDDLGLEAAGVQTDARGYVVVDDQLKTTVDHIWALGDCNGKGAFTHTSFNDYEIVAANLLDGDPRRVSDRILTYALYIDPPLGRAGMTVAQVRASGRKALVGKRPMTKVGRAVEKGETQGFMKIVVDADTHEILGAAILGVGGDEVIHAILDVMSARAPYTTLSRTMHIHPTVSELVPTMLQEMEPLD
>NZ_CP009483|515358:592647|542726_543809_+|WP_042313227.1|DBSCAN-SWA
MYSLVRRLLFLLPPERAHTFVFALLRAVTAVAPARRMLSRWLGPTDPVLASTVFGVRFPGPLGLAAGFDKDGTGLDTWGALGFGYAEVGTVTARPQPGNPPPRMFRLPADRALLNRMGFNNHGAGALAIRLTRHRPRVPIGVNIGKSKATPAGEAVDDYRASARLVGPLAAYLVVNVSSPNTPGLRDLQAVESLRPILTAVLAETSTPVLVKIAPDLSDSDIDDIADLAVELGLAGIVATNTTVSRDGLATPGVDELGAGGISGPPVAARAVQVLRRLQHRVGDRLVLISVGGIETVDDAWERITAGATLLQGYTGFIYGGGLWAKHIHDGIARRLHDGGFAPLADAGGPAARKAGKPPG
>NZ_CP009483|515358:592647|588677_590225_+|WP_080673990.1|DBSCAN-SWA
MSGAQLEVGNAEEVHSDTDFEVLIVGAGFGGIGAAIELIRKGVENFLILDKNDGVGGVWRVNTYPGVAADLPFLLYSYSYAPPRKCTRFFPTGAEVREYIEQIVDDYRLTDRILLNTNVAEAVWEERSHKWTVHLASGETLVSRFLICGIGPFSTAKMPDIPGIEDYQGKVIHTAQWDHDFNYSGNRIAVIGNGASGLQLIPELADIATSLVVFQRRPTWVAPKPDFAVPQFMSSLVRHAPLTRVFMRAVIAGMVDLLITGLSVFHKRVPFMIPLMQRIGSQAYFLSVRDRELSKRLTPEYAPYCKAVSISNRYLRTFTRDHVELVTVPIEKLTARDVVTRDGTLYEVDVLVCATGFKVMDDGAIPSFPTRGRNNTDLHRFWQEHRFQAYQGVSVPNFPNLFLITGPYAYPGGSWITMIECTSKHAARAIAAARARGATAVEIRSGPHDRYWRKCLRRARDTIWLSKRCAGSNSYVVDNHGDPVLIRPSLHCEMWWGNKRFPLGHYAYSTTPASC
>NZ_CP009483|515358:592647|540965_541268_-|WP_023364716.1|DBSCAN-SWA
MTVTADRHVANKQFAIEDMSTGIFASGYGQVGDGRSFSFHIEHRSLVVEIYRPRLTAPVPQAEDVVARSVRSLVDIDVTDERSLAAAVRDSVAQAVPVSR
>NZ_CP009483|515358:592647|540073_540904_-|WP_023364715.1|DBSCAN-SWA
MSWWQVISLAVVQGLTEFLPVSSSGHLAIMSRIFFSDDAGASFTAVTQLGTEAAVLVYFARDIVRILRAWVDGLVVKSHRNADYRLGWYVIIGTIPICILGLFFKDEIRSGVRNLWVVATAMVVFSGVIALAEYLGRQGRQVEQLNWRDAVVVGIAQTLALVPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSLPDAFHPVTEGMSATGPQLLVATLIAFVVGLSAVAWFLHFLLRHNMYWFVGYRIVVGVGVLVLLATGTVSAT
>NZ_CP009483|515358:592647|521151_521433_-|WP_023364701.1|DBSCAN-SWA
MKQSLAVKTFEDLFAELGDRARTRPAGSATVAALDAGVHWLGKKILEEAGEVWLAAEHEANDALAEEISQLLYWTQVLMISRGLSLDDVYRKL
>NZ_CP009483|515358:592647|521616_522447_+|WP_042313214.1|DBSCAN-SWA
MQWTTSGLRLRRRASRAGDLNWLFLPGGPGIGSESLHELVDTVDVPGCSWMVDLPGDGSNVNAPGAPADPYDLWPQVLLEAAHAVAHPVFVGHSTGGEYLLSVPALDGCLAGLALVSTAPDASWIPVFEHMTRNNRLPGVEYATTRYLSDPTDDHLRRVAVESAPWNFAAHTVARGTEILARLPYNARAAQWSEANFDRGYRSAWWPSTLPTLIVSGSADRIVTQTLWHDKRFHTPNTTWRVIAGAGHFPWIEQPAAVHDAFAALVGQIDNRRTTD
>NZ_CP009483|515358:592647|565768_566299_-|WP_023364727.1|DBSCAN-SWA
MTTPPDPYAALPELPSFSLTSDSVTNGQPLRTAQVSGIMGAGGQDASPQLSWSGFPKETRSFAVTVYDPDAPTLSGFWHWAVANLPAEVTELPEDAGAGKELPGGALTLVNDAGMRRYVGAAPPPGHGVHRYYVAVHAVDVEKLDLSEDASPAFLGFNLFQHAIARAVIYGTYQQT
>NZ_CP009483|515358:592647|528266_531845_-|WP_023364706.1|DBSCAN-SWA
MTAANKPRYDTDLLDVLAQRVVVGDGAMGTQLQAADLTLDDFRGLEGCNEILNETRPDVLETIHRNYFEAGADAVETNTFGCNLSNLGDYDIADKIRDLSEKGTTIARRVADELSTPERKRYVLGSMGPGTKLPTLGHTDYAVIRDAYTEAALGMLDGGADSILVETCQDLLQLKAAVLGSRRAMKQAGRHIPVFAHVTVETTGTMLLGSEIGAALTAVEPLGVDMIGLNCATGPAEMSEHLRYLSRHARIPVSVMPNAGLPVLGAKGAEYPLRPDELAEALSGFIAEFGLSLVGGCCGTTPAHIREVAAAVVGAPRPERQVSFEPSVSSLYSAVPFAQDASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDSTETPVLQAGLEHLGGRCAINSVNYEDGDGPESRFAKTMELVAEHGAAVVALTIDEEGQARTAEKKVEIAERLINDITTNWGVDESSILIDTLTFTIATGQEESRKDGIETIEAIRELKKRHPDVQTTLGLSNISFGLNPAARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEEQRTVALDLVYDRRRDGYDPLQELMRLFEGVSAASSKESRAAELAKLPLFERLAQRIVDGERNGLEADLDEAMTQKPPLEIINENLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKSDDDSGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVVNIGIKQPIATILEVAEDKSADVVGMSGLLVKSTVVMKENLEEMNSRGVAEKFPVLLGGAALTRSYVENDLADIYEGEVHYARDAFEGLKLMDTIMSSKRGEAPDVDSPEAIQARKKEAERKARHERSKRIAAQRKAAEEPVEIPERSDVAADIEVPAPPFWGSRIVKGLAVADYTGMLDERALFLGQWGLRGQRGADGPSYEDLVETEGRPRLRYWLDRLSTDGILAHAAVVYGYFPAVSEGDEVVVLTEPAADAEERYRFRFPRQQRGRFLCIADFVRSREHARERGQVDVLPFQLVTMGQPIADFANELFAADSYRDYLEVHGIGVQLTEALAEYWHRRIREELRYSADRTMAAEDPDAVEDYFKLGYRGARFAFGYGACPDLEDRAKMMQLLEPDRIGVTLSEELQLHPEQSTDAFVLHHPEAKYFNV
>NZ_CP009483|515358:592647|538698_539286_-|WP_023364713.1|DBSCAN-SWA
MARAIHVFRTPDRFVAGTVGQPGNRTFYIQAAHDDRVVSVVLEKQQVAVLAERIGALLLEVNRRFGTPVPPEPAEVEDLNPLIMPVDAEFRVGTMGLGWDSEAQTVVVELLAVTDAEFDASVVLDDTDEGPDAVRVFLTPESARQFATRSNRVISAGRPPCPLCQEPLDPQGHICARTNGYRRDLLFGSDDEPEQ
>NZ_CP009483|515358:592647|536606_537395_-|WP_023364711.1|DBSCAN-SWA
MSPAADDLTDAQLAADLAAEAGELLLALRDEVGFDHPWALGDAGDARANSLLVRRLRAARPGDAVLSEEAHDDLVRLKCDRVWIIDPLDGTREFSTRGRDDWAVHVALWQRTTNGRPQITDAAVSLPARGNIVYRSDTVTADAAPTGIPDVIRVAVSANRPPAILHYIQQTVDIELVRIGSAGAKAMAVIDGYADAYLHAGGQWEWDSAAPAGVVLAAGMHASRLDGSPLQYNQLDPYLPDFLMCRKELAPVLLGAMRRTWR
>NZ_CP009483|515358:592647|552068_562223_+|WP_023364722.1|DBSCAN-SWA
MDFAGLPPEHNSARMFAGAGSAPMLATAAAWQGLAAELGSSAFAFASQTSALAGSAWQGPASAAMADAAATYVGWLNAAAVQAEQAASQARLAAAAFEAARAATVHPAIISVNRARLLRLVAWNVLGQSAPAIAAAEAEYEQMWAQDVAAMFGYHAEASAVAAVLTPFPSTLQALAGLPGPGAGAGLAGTSFAGPAQAVVDPLGRAGLNLGFANAGSGNVGNGNIGSFNIGSANIGSANIGSGNVGSTNLGFGNTGPSLTAASRNIGWGNTGSTNIGFGNTGNANIGFGNTGDGNIGIGLTGDGRAGLGGLNSGTGNVGLFNSGTGNVGIGNSGTGNWGIGNSGNSYNTGIGNSGEANTGVFNSGVANTGVANAGNYNTGSYNPGSTNTGGYNGGSYNTGLLNRGNYNTGVANTGNADTGALISGDYSNGLLWRGNYQGLMAPGFGNSTDMPSSGFFNTGSGSASGIANSGANNSGFFNASDVGISGYYNTGALESGVVNSGNTVSGVFNESLLDVAVPAVVSGVLNTGSDLSGLRGGPSSLNLGFANHGGANIGNANIGDSNFGSGNVGNSNIGRGNVGDTNLGSGNIGSTNIGNGNIGDGNLGFASIGIDNFGSGNLGDYNIGPGNIGAHNRGFWNAGSSNIGFANAGDFNVGFANTGSNNIGVGLSGNGEVGFGALNSGSANIGLFNSGTGNIGLFNSGTGNIGIGNSGTGNWGIGNTGTGNTGIDNSGSLNTGVVNAGSTNTGVSNAGSYNTGFVNAGSTNTGSYNTGQHNTGGFNPGNYDTGYFNSGNVDTGAFNTGNYSNGLFVTGDNQGQISAHLAIDIPTVPIDVESVNPINQTMVVGGQEYTIPGYTYPKTYFLDGDFYLGPVSISSSTVTGPTVTIDIGGPATSIDATVIGALQGGTIQIIDIPAAPGFGNSTASPSSGFFNSGTGSASGFGNAGADTSGFRNLSVGSGGVSGYRNVGSLESGLANWGNTISGVYNTGTQGLTAPGNLSGYANTGTNLAGVLRDSATGTVFNAGLANIGALNVGFGNTGDYNLGSGNVGNLNLGSGNLGSTNLGSGNIGNGNIGFAHNGDGNLGLGNTGSHNIGAGNTGDGNIGFGNTGNGNIGIGLSGDGQTGFGALNSGSGNTGLFNSGTDNVGIANSGTGNWGIANSGNHNTGLANAGNTNTGWFNTGLANTGIANTGNYNTGSYNTGATNTGSFNPGNTNTGLFNPGSYNTGLANTGNINTGAFNTGNMDNGWWWRGDSQGLIGAYYAITVPEIPLNVVATIPIDIPIKASFTTTVYHGITIDDIPFGTTVTLGPIPVLQGTVNSLTIPPISATGPAPAIQIGSPDGSTAIVIPVSASLGPADWTIIDIGGAPGFGNSTTSPSSGFFNAGTGTASGFANFGADNSGLLNASSGSSGYKNVGDLVSGMANLGNTVSGLLNTSTLDLATPANVSGVANIGANLSGLYRDSAAAMSTFNVGFGNVGTLNVGFGNIGDYNLGSGNVGDLNVGSANVGNHNVGGANIGNVNVGFGSHGLHNIGSANLGNDNFGPANFGDDNRGFANAGNANIGLANTGDGNIGLANTGSNNIGIGLTGNGKVGIGALNSGSGNTGLFNSGTDNAGLFNSGTGNVGIANSGTGNWGIGNSGSTNTGFGNSGMVNTGLWNAGNVNSGIGNTGDYNSGSFNAGSFNTAGFNPGSYNTGYSNTGSYNTGLANSGNVDTGLFNSGSYDNGILWRGDYQGLLGYNYTIYIPDTAIPVNLDVEIPIDIPISATFGILTIEGFTIPKYTADITVLDAGTTQAISVGPLTVSDIVVSLPPLATTIGGPTTAIDITGTGGIGPIAIPVIDIPPAPGFGNSTVLPSSGFFNSGAGSSSGLANVGPNNSGFFNASGNSGISGYKNVGDLVSGMANFGNTVSGLLNTSTLDLGTPANVSGVANVGSDVAGFFGNSAVSNLGFANDGSLNVGSGNVGNLNVGSGNVGTHNVGGANIGSFNVGFGSHGLDNFGSGNLGNDNVGPANVGDHNLGVANAGDGNAGFANTGDLNIGFANTGSNNIGIGLTGNGKVGIGALNSGSDNIGLFNSGTGNVGLLNSGNGNIGIANSGTGNIGIGNSGTANTGVANAGRHDTGLWNPGTGNTGIANAGADNSGAYNTGSTNTGIANPGSYNTGSYNTGSTNTGLANTGDYNTGVANTGDYNTGLANTGNVDTGAFIAGNYSNGFFWRGDYQGLYGFHAGIYIPEFPVLNMGIDIPINIPINLDAANILVNPFAIQPITVSVLGSSYLSITFGTISIPALSGNGLAVDALIGGPDTSIPITITSALGPIDITFIDIPAAPGFGNSTASPSSGFFNSGTGSASGFGNAGADTSGLRNLGGAGVSGYRNVGSLESGLANWGNTVSGVYNTSTQGLTAPGNLSGYANTGTNLAGVFHNSTIPAGRVLNLGMANAGQLNMGFGNTGNINLGGGNVGDLNVGSGNLGSTNLGSGNIGNGNIGFAHNGDGNLGLGNTGSHNIGAGNTGDGNIGFGNTGNGNIGIGLSGDGQTGFGALNSGSGNTGLFNSGTDNVGIANSGTGNWGIANSGTGNWGIANSGNHNTGLANAGNTNTGWFNTGLANTGIANTGNYNTGSYNTGATNTGSFNPGNTNTGLFNPGSYNTGLANTGNINTGAFNTGNMDNGWWWRGDSQGLIGAYYAITVPEIPAFFNVAIPVDVPITISITDIEINAVTIPKVSFSGLDDGIGGKVVGSIGPVSVYGAQTGDPIVISFGDQPAVALNVGNPDGTTVINITGTGGLGPISIPIVDVPAAPGFGNSTTSPSSGFFNAGAGSASGFANFGANNSGLWNVSNAIAGNSGYLNYGSLQSGVANFGNTISGLYNTGTVGLESPANVSGIASIGTDLAGVLRDGPTATAFNAGLANIGAGNVGFANIGDVNLGSANIGGYNLGSGNVGDLNVGSGNLGGTNLGSGNIGSANIGFANTGPSLTPAVHNVGLANTGNHNVGAGNTGDGNIGFGNTGNGNIGIGLSGDGQVGFGALNSGSGNIGLFNSGADNVGIANSGTGNWGIGNSGSYNTGIGNTGSTNTGWFNAGLANTGIANAGSINTGSYNTGANNTGSFNPGNANTGLFNPGSYNTGLANIGNSNTGIANSGNVDTGAFISGNYSNGFLWRGDYQGLITISYSSTIPEIPWHYDVTAPIEIPISGNVNEITQEEFHISSIPIKVQLQQTICFLGYCTTITTTVYDGSVGGWALGPYTLLTPTAIDDTITQTFDLPGSGTLGPYTFGFAYQQSPGFFNSTTDPSSGFFNSGGGGASGLFNSAPGAVSGLANAVADSSGLGNAGGTGNSGYLNYGGLVSGFANLGNTMSGFFNTSTVDLTQAAFDSGIGNVGINLSGVFNDIFVP
>NZ_CP009483|515358:592647|583736_584237_+|WP_080773665.1|DBSCAN-SWA
MSVYRYRGSVWRRYDKMRRLPNGLLVTGDALCSFNPIYGQGMTMAALEAVTLRDCLSHPNGDLGRQFFRAMAQQIRPIWATNQINDLYMSEPGGGRSTLMRVWNWSNDKVLTAAERDPILTERLFRATNLIDPPTRLLDPFLMSRVCLNLWRQRQSQRATYAINHR
>NZ_CP009483|515358:592647|591447_592647_+|WP_023364757.1|integrase|DBSCAN-SWA
MDTTVSGIGAVVVAELRAAGYMESTVGQYAKTIKALTEFASGREYSTGLGVEFASMTTSVRTGRFSAQRRFDYRRLVTVFDSYVQTGRVDLAVRGRGGGGPRPVGGDFVALDATWEAEMGRRGLAPATREAYGRVARSYLVFVERRGIAVLDGADGASVLAFLESILDRWARSSLFWVVSNFRPFLKFTGRADLVNALNLAGVKRFHAIVPLLGDADEELVVRACASGVVSARDAAITLLALTTGLRACDIVALRIGDVDWRGHTIGIVQQKTGNPLTLPLPALLLGKLASYVLDERPSSGDDHLFLRMKAPHTRLNDHATVHRVTVETFRKAGVAEAKAGTRLLRHNAASRLLAAAVPLPTIAAVLGHASEESTNLYMSVDRRRLLDCVLPVPEAVRS
>NZ_CP009483|515358:592647|562401_563652_+|WP_023364723.1|DBSCAN-SWA
MNNTDIEKVLRKQRLRSLQGGSILRVGVAVIMFSAMPSVTDPARLPEQAVLLGVYAVVTIGALLLTYAGTSQLLNDDRALLTLALTDVAAVFGFKLLSPGGFIPLLVMALLPRMVAVELSLRRAGVVLACAFAVFTASVLQDPMIMRRIGPWETAVIVLVYGFICGTALLVVIFRLRNIDELAELTTSREALLAETMNASQAERRQISEFIHDGPLQDVLAARRDIAGFLKRSPDAPLEQALASLQDASRLLREATFELHPALLDQVGLAAAVEKLVAVTAARSGMAITTEIDYPEPNAIDPILFGVIRELVSNVARHSQASSATVKLTVDGEVARIDVADDGIGITGDVAARRLAQGHIGLASHRARVQAAGGTLTILEEPVGARLRVEVPLRRPAATSGPATVPHGTDRQSQRC
>NZ_CP009483|515358:592647|564706_565111_+|WP_023364725.1|DBSCAN-SWA
MKITAIAAAGLMAGMLLTASPAHAELTAKPQASGVRPLQPAPRMEPDPRSEVQELLQQISDLDDSWDSLTPQQRVAQLQQQVTVVDRGTRNLPADQQPEVQAMLSMAVVKLVDLVMKAQPPGSPCYFPFCLPGL
>NZ_CP009483|515358:592647|542493_542700_+|WP_042311690.1|DBSCAN-SWA
MSDEYEWAPLRLPPEVTRLSASTRLSIEAEYRGWELTRVRLYTDGSRRVLLRRKKSRLDNASSDQPEP
>NZ_CP009483|515358:592647|549673_551629_-|WP_080773664.1|DBSCAN-SWA
MSFVLASPEVLAAAAADVVRIGSVLRSANAAAATPTIAVSAPGADEVSAAVASLFAGHGQAYQRLSAHLTAYHDQFVRTLQSSADAYAGAEAANAAPLQSAGQGLLNLINAPTEALLGRPLVGNGADGASGPVGQPGQSGGILYGDGGNGGNSGAPGAAGGAGGSAGLIGNGGAGGTGGAGALGGNGGNGGLIYGNGGPGGGGGTGAVGGAGGAALLLGNGGAGGAGGAGGAGGAGGNALLLGSGGDGGAGGAAAAGINGGNAGRGGDGGYAGLWGNGGNGGHGGAGATGMNGANPSANGAAASGGTAGTSVSVTNPTDAWATGTDGGTGGIGGTGWAGGTGGQGGNAHASSTDTHGGQNSVSAQGGNGGQGGIAGAGGAGGAGGAGGAATATSSNTNNLPNTVEATGGKGGNGAAGGAPGGAGGSGGPGGNATSSTQSVDINRAIGGRGGNGGDGAIGATGGAGGAGGTGGNGGHGGRLGGNGGSGGAGGAGGTGGVGGFGGVGGNGGGGGASNTATAGNGGDAGDGGTGGIGGAGGIGGSGGNGGAGGLLAGSGGVGGAGGVGGDGGGGGTGGNGGDGGASGGTGGQVGLRGDGGAGGTGGASGMGGSGGSGGTGGVLSGAAGSGGAVGESGTAGGEGMRGMPGAGRVA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023364695.1|515358_516201_-|tRNA	tRNA (adenine-N1)-methyltransferase	NA	NA	NA	NA
WP_023364696.1|516274_517144_+	RecB family exonuclease	NA	NA	NA	NA
WP_023364697.1|517140_517944_+	thioesterase family protein	NA	NA	NA	NA
WP_023364698.1|518307_519687_-	mercuric reductase	A0A2K5B2C5	Erysipelothrix_phage	1.5e-60	33.3
WP_036395983.1|519683_520169_-	membrane protein	NA	NA	NA	NA
WP_036393190.1|520294_521149_-	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_023364701.1|521151_521433_-	phosphoribosyl-ATP diphosphatase	NA	NA	NA	NA
WP_042313214.1|521616_522447_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_036393185.1|522741_524229_+	arylsulfatase	A0A2P0VMN7	Tetraselmis_virus	5.1e-107	42.8
WP_023364704.1|524248_526603_+	arylsulfatase	NA	NA	NA	NA
WP_042313221.1|526701_527949_-	PPE family protein	NA	NA	NA	NA
WP_023364706.1|528266_531845_-	methionine synthase	NA	NA	NA	NA
WP_042313224.1|531964_532819_+	PAC2 family protein	NA	NA	NA	NA
WP_080674189.1|532815_533994_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_023364709.1|534022_534916_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_023364710.1|534940_536185_-	cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	A0A1V0SAQ2	Catovirus	1.5e-27	25.4
WP_023364711.1|536606_537395_-	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_023364712.1|537899_538715_-	phosphatidylinositol kinase	NA	NA	NA	NA
WP_023364713.1|538698_539286_-	DUF3090 domain-containing protein	NA	NA	NA	NA
WP_023364714.1|539348_540077_-	phosphoglycerate mutase	NA	NA	NA	NA
WP_023364715.1|540073_540904_-	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_023364716.1|540965_541268_-	hypothetical protein	NA	NA	NA	NA
WP_036393495.1|541390_542440_+	lipoprotein	NA	NA	NA	NA
WP_042311690.1|542493_542700_+	dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_042313227.1|542726_543809_+	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_080673987.1|549520_549979_+	PPE domain-containing protein	NA	NA	NA	NA
WP_080773664.1|549673_551629_-	PE family protein	NA	NA	NA	NA
WP_023364722.1|552068_562223_+	PPE family protein	NA	NA	NA	NA
WP_023364723.1|562401_563652_+	ATP-binding protein	NA	NA	NA	NA
WP_023364724.1|563746_564394_-	DNA-binding response regulator	NA	NA	NA	NA
WP_023364725.1|564706_565111_+	hypothetical protein	NA	NA	NA	NA
WP_023364726.1|565080_565722_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_023364727.1|565768_566299_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_036393176.1|566333_567686_-	hypothetical protein	NA	NA	NA	NA
WP_023364729.1|567881_569528_-	serine recombinase	NA	NA	NA	NA
WP_042311693.1|571207_572650_-	cell division protein FtsK	NA	NA	NA	NA
WP_041327080.1|572738_573074_-	hypothetical protein	NA	NA	NA	NA
WP_042311696.1|574439_575180_+	creatininase	NA	NA	NA	NA
WP_023364735.1|575816_577211_-	sensor histidine kinase	NA	NA	NA	NA
WP_036393174.1|577207_577912_-	DNA-binding response regulator	NA	NA	NA	NA
WP_023364740.1|578519_580463_-|integrase	integrase	A0A1B1P7C7	Bacillus_phage	4.3e-05	24.4
WP_036393475.1|580459_581494_-|integrase	integrase	A0A166YH27	Gordonia_phage	4.9e-08	26.3
WP_023364744.1|581565_582627_-|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.3e-66	43.8
WP_036393171.1|583127_583367_-	hypothetical protein	NA	NA	NA	NA
WP_080773665.1|583736_584237_+	hypothetical protein	NA	NA	NA	NA
WP_080673988.1|584544_585381_-	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_023364748.1|585881_586601_+	hypothetical protein	NA	NA	NA	NA
WP_080673989.1|586864_588301_-	cytochrome P450	A0A2I2L481	Orpheovirus	8.5e-27	22.4
WP_080673990.1|588677_590225_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_023364752.1|590443_590752_+|transposase	transposase	A0A1B3AZF8	Gordonia_phage	4.2e-08	38.5
WP_023364754.1|590748_591390_+|transposase	IS3 family transposase	U5P429	Shigella_phage	1.1e-13	31.3
591306:591365	attL	NA	NA	NA	NA
WP_023364757.1|591447_592647_+|integrase	integrase	NA	NA	NA	NA
WP_023364757.1|591447_592647_+|integrase	integrase	NA	NA	NA	NA
594672:594762	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP009483|2361670:2392391|DBSCAN-SWA
GTTGCGTATCGGCTCAATCGAGCTTGCCAGCCCGGTTGTGTTGGCACCGATGGCCGGTGTGACGAATGTCGCGTTCCGCACCCTGTGCCGTGACTTCGGTTCGATGCGTGGCGACCCGCTGCGTCCGGCTTCACCGCCCTTGCGATCGCCACGAGAACAGGCGAAGGTCGGCACGGTCGGCGGACTCTACGTCTGCGAGATGGTGACGGCCCGCGCGCTGGTCGAGCGGCATCCGGTCACCATGCACATGACGACGTTCGCCCCGGACGAATCGCCTCGCTCGCTGCAGCTCTACACCGTCGACCCCGACACCACTTACGCGGCGGCGCGAATGATCGCCGACGAAGGCCTGGCCGACCACATCGACATGAATTTTGGGTGCCCGGTGCCCAAGGTCACCAAGCGCGGTGGCGGGGCGGCCCTGCCGTTCAAGCGACGGCTGTTCGGCCGGATCGTGGCTGCGGCGGTGCGTGCCGCCGAAGGCACCGGGATACCTGTGACGGTCAAGTTCCGCATCGGCATCGACGACGCTCACCACACCCATCTGGACGCCGGCCGCATCGCGGAGGCCGAAGGTGCCGCCGCGGTCGCTCTGCACGCCCGGACGGCCGCGCAACGGTACTCCGGCACCGCCGACTGGGACCAGATCTCCCGGCTCAAGCAGCAGGTCACGACCATCCCGGTGCTGGGCAACGGGGACATCTACGATGCCAGCGACGCGCTAGCCATGATGGCCACCACAGGATGTGACGGCGTTGTCATCGGCCGCGGTTGCCTGGGCCGACCATGGCTGTTCGCCGAGTTGTCGGCCGCCTTTACCGGCCGCCCGGCTCCCACCCCGCCCACACTCGGTGAGGTCGCCGACGTCATCCGCCGCCACGGAGCCCTACTGGCGGCACACTTCGGTGAGGACAAGGGCATGCGCGATATCCGCAAGCACATCGCCTGGTACCTGCATGGGTTCCCGGCCGGATCAGACGTCCGGCGAGCGTTAGCGCTGGTCAAAACGTTGAGCGAACTCGACGACCTGCTGAACCGGTTGGACGGCAGCGTCCCGTTCCCGAGTGCCGGCAACGGCCCCCGCGGCCGGCAGGGCTCACCCGCCCGGGTGGCCCTTCCCGACGGTTGGCTGGACGATGCCGACGACTGCCGGGTGCCCGACGGAGCCGACGTCATGCATTCTGGTGGTTGAACCGAAACTCTTCCGAGATCGCGTCTGCGACCACAAGTCAGTACGATGTGGGCTTTATGCATGGCGCGGCGCCGATCGGCTCGGCGCTGCGCTGACGTGTGCGCACGGACAACCCAGATGTCCGGATCATATTTTTCGGAGGCCGATGGGACATGAGTGACGGCGACAAAGACGCCACTCCTGACCTTCGGCGCGTGTCCGGCTCCCGCGACGACGCCCAACCGGTCACCCTGAACCCGCCGGCGACACCGGGCGCCGCGCCGTGGGAGCGGTTGTTCGCGCCGCCGCCCGAGGACAGCTTGCTCCGCTGGTCGGGAGTGTCATCCGGCGATGCGGCCGGACATCACGGCGGCCCGGACCACGCAGAGCCCGCAGAGGTCGGCTGTCACGTCAACGGCGGAGTCAGCGTCGCGGAGCTGATCGCCAAACTCGGCGCACCTGCGCCCGCCCACCCATCGCCACAGCGCGCCGGACCCCGATCCCGTCGCGGAGCCGTCGCAACCATCCCGGATGGACGTGGAGGTCCCCGACGACGACGCGGACCAACTGGACACCCAGGTCATCGCCATTCCGGCCTACTCTTCAGAACTCCTCTCCGAGCTGCCCGACCTCGGGTCGGCCGCCTTCGCACCGGATACCGTCGCCGCCGAGCCACCCGAGGGCGAGCCGGCCGCGTCGTCGCGGGCGCCTGTCGTCAAGCGCTCAAAAACCCCGAAGCGCCGGGAGAACCGGGCAAAGAAACGGCGTTCGCGCCGGCGGCCGATGCTGCTGGCCGGGCGGTCACTGGCGGCCATGTTCGCCGTGCTGGCGCTGGTCCTGACCGGCGGGGCGTGGCAGTGGAGCGCATCGAAAAACGAACGGCTGAACACGGTAAGCGCGCTCGACCCGAACTCCGGCGATATCGTCGACCCCAACGGGCAGTACGGCGACGAAAACTTCCTGATCGTCGGCATGGACTCGCGCGCCGGCGCGAATTCCGAGATCGGTGCCGGTGACACCGAGGACGCCGGCGGTGCCCGGTCGGACACCGTCATGCTGGTCAACATCCCGGCGAACCGGAAGCGGGTGGTGGCGGTGTCGTTCCCCCGCGACCTGGCGATCACCCCGATCCAGTGCGAGGCCTGGAACCCCGACACCGGCAAGTACGGGCCCATCTATGACGAGAAGAAGGGGACGTGGGGTCCCCGGATGGTCTACACCGAGACGAAGCTGAACTCGGCGTTTTCTTTCGGCGGCCCGAAGTGCCTGGTGAAGGTCATCCAGAAGCTGTCCGGCCTGAGCATCAACCGCTTCATCGCCATCGACTTCGTCGGTTTCGCGCGAATGGTCGAAGCCCTCGGCGGCGTCGAGGTGTGTAGCACCACTGCGCTGCGCGACTACGAATTGGGTACGGTGCTCGAACACGCCGGACGTCAGATCATCGACGGGCCGACCGCGTTGAACTATGTGCGAGCCCGCCAAGTCACCACCGAGAGCAATGGCGACTACGGTCGCATCAAACGTCAGCAATTGTTCTTGTCGTCACTGCTGCGTTCGCTGATCTCCGAGGACACGTTGATGAACCTCAACAAGCTCAACAACGTCGTCAACATGTTCATCGGCAACAGCTACGTGGACAACGTCAAGACCAAGGACCTGGTACAGCTGGGCCAGTCGTTGCAGCACATGGCGGCCGGCCACGTCACGTTCGTCACCGTGCCGACCGGCGTGACGGACCAGAACGGCGACGAACCGCCCCGGACGGCCGACATGAAAGCGCTGTTCGCCGCCATCATCAACGACGATCCGCTGCCGCTGGAGAACGACCACAACGCGCAGACGCTGGGGAACTCGCCGACGACGGCGCCGACCACGACGAAGAAGACGCCCCCGCCGAACGGCACCGGCGAGGTCCAGCGCGAACAGGTGATCACCACGTCGCCGCAGGAAATCACGGTGCAGGTCTCCAACGGGACCAGCACCGCCGGCCTGGCGACCACCGCAGCCAACCAGCTCAAGCGAAACGGCTTCAACGTGATGACGCCGGACGACTACCCGAGTTCGTTGAAGGCCACCACGGTGTTCTTTTCCCCGGGCAATGAGCAGGCCGCAGCAACCGTGGCCGCGGCGTTCGGCAATTCGAAAGTCGAGCGGGTCACCGGGATCGGACACGTGGTTCAGGTAGTCCTCGGCCCGGATTTCAGTTCGGTGACCACCCCGCCGCCCAGCGGCTCGTCGGTCAGCATGCAGATCAACCGGAATTCCAGCACTCCGCCGACCAAGCTGCCCGAGGATCTGACCGTCACCAACGCCGCCGACACCACCTGCGAGTAAGCGCTTCACGGCGTATCCGGCGTCGAGAACGTAGGCTTTATCACATGCGAACCGCTTACCACGAGCAACTCTCGGAATTGTCCGAGCGGCTCGGTGAGATGTGCGGGCTGGCAGGCATCGCCATGGAGCGGGCGACCCAGGCCTTGCTGCAGGCCGATCTGGTGTTGGCCGAACAGGTGATCTCCGACCACGAAAAGATCGCAACGCTGAGCGCCCGGGCCGAGGAAAGCGCGTTCGTCCTGCTGGCACTGCAGGCCCCGGTCGCCGGTGATCTCCGGGCAATCGTGAGCGCGATCCAGATGGTGGCCGATATCGACCGGATGGGCGCACTTGCCCTGCACGTCGCCAAGATCGCCCGCCGGCGGCATCCGCAGCATGCGTTACCCGAAGAGGTCAAAGGATACTTTGCCGAAATGGGCAGAGTCGCAGTCGAATTGGGAAACAGCGCGCAGGAGGTCGTGTTGTCCCGCGACCCGGAGAAAGCGGCCCGGATCCGCGAGGAAGACGACGCGATGGACGATCTGCACCGGCATTTGTTCAGCGTTCTGATGGACCGGGAATGGAAGCACGGCGTGGCAGCGGCGGTCGACGTGACGTTGCTGGGCCGGTTCTACGAACGCTTCGCCGACCATGCCGTCGAAGTGGCGCGACGCGTGATCTTCCAGGCGACCGGGAGGTTTCCCGAAGACGAAACGACGCCTCACTCGCGCTAATTCGACCGCGCTAGCCGAATCGGCCGGAGATGTAGTCCTCGGTGGATTTCTGGCTCGGGTTGGAGAAGATCTTCTCGGTGTCGTCGATTTCTATCAGGCGGCCCGGCTTGCCCACGGCCTCCAAATTGAAGAACGCCGTCTGATCGCTCACTCGGGCGGCCTGCTGCATGTTGTGCGTGACGATGACGATCGTGTAGTCCTGCTTCAATTCACTGATCAGGTCTTCGATTGCCATCGTGGAGATGGGATCCAGCGCCGAGCACGGCTCGTCCATCAGCAACACATCGGGCTGGACGGCGATGGCCCGCGCGATACACAACCGCTGTTGCTGGCCGCCGGACAACCCGCCGCCGGGTTTGTCCAGCCTGTCTTTGACCTCATCCCATAGGTTGGCGCCGCGCAGCGAATATTCGGCGGTTTCGTCGAGCACCTTGCGGTTGCGCAGGCCCTGCAACTTCAGGCCGGCGACCACGTTGTCGCGAATCGACATCGCGGGGAACGGGTTGGGCCGCTGGAAAACCATTCCGATCGCCCGCCGCACCCCGACCGGGTCGATGCCGGGCCCGTAGATGTTTTCGTCGTCGAGCAGCACGGTGCCTTCGACGCGCCCGCCGGGCACCACTTCGTGCATCCGGTTCAGCGTGCGCAACACCGTGGTCTTGCCGCACCCCGACGGGCCTATGAATGCCGTCACGCTGCGAGGCAGAATCGACAAGGACACATCGGCGACGGCCTGAAACGCCCCGTAGTAGATGTTGACGTCCTTGAGGTCCAACCGCTTGGCCACTGAGTGCTCCTGCCTACGACTTCTTGGGGACGAGGATGGCGGCGACCACCCTGGCGCCGATATTGATCATCGCGATCAGCAACATCAGCGTCAGCGCGGCGCCCCACAGCCGCTCTGTGGGGACCGGGCTGATGCCGGCGCCCGCCGTCGCCTGGTCATACATCATGCCCGGCAGCGACCCCATGAACCCGCTGAATATGTCGAAGTTCATTGTCTGTGCATAACCAACCAGGATCAGCAGCGGCGCCGTCTCGCCCATCACCCTGGCCAAGGCCAGCAGGATGCCGGTCACGATGCCGGACAACCCGGTCGGGATCACGATCTTGGCGATGGTCTTCCACTTGGGCGCTCCCAGCGCGTAACTCGCCTCTCGCAGATCTACCGGGACGATACGCAGCATCTCTTCGGTCGAGCGCACGATCACCGGCAGCATCAACAACACCAGCGCCAGTGACACCGCAAGTTGGGAGCGGGGGAAGCCCAGGACCGCGACCCACAGCGCATAGATGAACAGGGCCGCCACGATCGACGGCACGCCGGTCAGGATGTCCACCATGAAGGAGACCACCCTGCGCAGCGCGCTAGCGCCACCGTATTCGACCAGATAGATGGCCACCAGGACGCCGATCGGGATGGATATCGCCGCACACACCACACCCTGCAACACCGTGCCGACGATTGCGTGGTAGGCACCACCGCCGGCTTTCAACGACGTCATCCCGGCCTGTGAATGCGTCCACCAGGTGCTCGACAGGACCGTCCGGAGGCCGTTGACCAGCACCGAGCACAGGACCCACGCCAGGGGTGTCAGCGCGATCGCCATCGATAGCGTCACCAGCACGGCGGCCATGTTGTCGGTGACTCGACGGCGCCGGCCTAACGCGGGCAGTGCACGCGCTTTGACGGGCCGGTCCAGCATCGAGGTCATCGGGTGGCCCTTCCCGCTCCGGCCAGAGCCGCGCGTGCCGCGGCGTTGACCACGAATGTGAGCAGGTAGAGCATCAGTCCCGCGGCCAGGTAGGCACCGGCTTGGTAGGGGTTGTCGAGGCCCGATGCGGCGGCGGCGATCTTGGTGGCGAAGGTCGAACCACCATCGAACAGTGACCAGCCGAAGGCTTGCTGGGTACCGTGCAAGATGATCAACAGCGCGACCGTTTCTCCCAGTGCCCGTCCCAGGCCCAGCATCGCGCCGCTGATGTATCCGGACCGTCCGAACGGCAACACCGTTGTCGTGACAACCTCCCAGCGGGTGGCGCCGAGCGCCAGCGCCGCCTCTATCTGGCCGTGCGGGGTCTGGGCGAACACTTCGCGCGTGACCGCGGTGATGATCGGCAGGATCATCACCGCCAGGACGATGCCGCCGGTGAAGACGTTGCCCCCGCCCCCAATTGAGGTATTGCCGCCGGCGAACAGGAAACAGTGACCCAGGGTGTGGTTGAGCGAGGTCGCGACGGGTCGCAGGTGTGGCGCCAGCACGTGCAAACCCCATACGCCGTAGATGATCGACGGCACCGCGGCCAGCAGATCGACCAGGTGGGCCAGCGGCATGGCGAACCGTCGCGGCGCATACTGCGTTAGGAATATGGCGACACCCAGCGCGACGGGCATGGCCAGCACCAGTGCGAACAGCGATACGAACGTGGTCACTCGCAACAGATCGAGGATTCCGAAGTGCATCGCCGAGGGGTCGGCGGTCTTCCAGGTTCCGCCGTAGGTCAAGAAGTTTTCTTTGTTGCGCGCCAGCGCCGGTATCGCACGCCACAGCAGAAACGCGCCGATCGCGGCGATCAGAACGATGATCAAGACGCCGGAACCCTGCGATAGCCCGCGAAACACCCGGTCCCCCAGACCCGGTTTGCCGGTACCCCAAGGGTTGATGGAGGTTGCCGGCGGCTCCGGAAAAGGCGCAGCAACGATCGCACCCGCCTCGGCTGGGTCGGGCACTGTCACTGCGATCCCGTCGATCCTGTCACTGCGGTGCTTGTTGGCTCCTCTTTTATCAGCGTCGTCCGTGGTCAAGCAGTCATTGCAGGGCGTTTATGGCGGTGACCAGGCGTTCTTCCACCTTATCTGGCACCGGAACGTAGCCGGCCGACGGAAGGCCGGTCTGACCGTTGTGGACGGCAGTGGTGAGAAACGCCTTGACCGCGGCACCGATGTCGCGCGGGTATCCCTTCGAGCACACAATCTCGTAGGTCGCCAGTACCAACGGGTAGGCGCCCGGGTCCTGGATGGCGAAGATCGAATTCAGGTCCAGAACGAGGTCGTTTCCGTTGGCCGCAAAAGTGACGGAGTCGATTGCCTTGCGAGCCGTTTCCTCGGTGAGCGGTACGACGTTGTTGCCGGTGTCGATCTGGGCGAACGGTATGCCGGCGCGGTCAGCGAAACCTTTCTCGACATAACCGATCGAACCTGGCGTGACCTGTACGGCTTGGATCACACCTGCCGACCTTTCGACGCCTTCCCCGACACCGCCGTGAAACTCGCCGCCGACACCTCGGCTCCAGCTTTGTGGCGCGGCGGCGGTCAGGTACTTCTGAAAGTTGTCCGTGGTTCCCGACGAATCCTTCCGGTACACCGGGATGATTTTGATATTAGGAAGTGCCACACCAGGATTGAGGGCCGCAAGGATCGGGTCGTTCCAGGTCCGAATGGACCCGCTGAAGATCTTTGCCATCGCATCGGCGTCGAGAACCAGGTTCGTTACGCCAGCGAGGTTGTACACCAACGCAATTGGCCCGAATACCAGTGGCAGGTCCCAGGCCGGGTTTCCTTTGCAGCGGTCGGCCGCCGGACCGATCTGCTCGGCGACCAGGGGCGAGTCCGATCCCGCGAAGTCGACATGACCGGCGATGAACTGCTCGCGACCGGCCCCTGACCCGGTCGGGTTGTACGACACTTTCTTACCCGGACACGCCTGGCCCCATGCCTGGTTGAACAACGCCATGGCATTCTGCTGGGCAGTCGATCCCTCTGCCGTCAGCGCATCTCGGCCGCTGCAGTCGGCCTTTGGCAACGGCGCTGCGGAGCCATTCGCCGAGGAAATACCGGGGTTTTGATCGCTACCGCATGCGGTGAGGGTCCCACCGCAAGCGGTGATCACCGCCACCGCCGCCGCGAATGCCCTGACCACCGTATCGAGCCTCATCGATCTCGCTCCCTGAATGCATTTACGACGATTGCGGCGCTGCACGGCCGTCTTCAGGACGAATTGCCAAGTCAACCATTAACTATGCGTCGTGCCGGAACTTGCCGGTTGGCGATCGTCAGCCGAGTGCCGGATCTGAGCAGGCCAGCGCGTAGGCCGTGTCGACGCTATGGGTGACAAATCCCAGGCTGTGATAGGTCCGCATGGCCGCGACGTTGTCCGATTCCACATACAGCATGACGGTGGGTTCTTCGGCAGGGTTCACGCCGGCCAGCCGCCGCGCCAACGAGCTGAGACCAATCAACGTCAACGCCTTGCCGAGCCCACGCCCTTGCGCTACCGGATCGACGCCGAGAACGTAGACCTCGCCAAGGTCAGGCTGGTGGTGAATCTTGGTCCAGTGGAAACCCAGCAGCTTCGCCTCGTGGCCCGGGGAAGCGTCGAACGCCAGGATGAGGCCCGCCGGATCAAACCAAGGTTCGCCGCGCCGCTCGGCCAGCTGTTGTTGGGTCCAGCCACCTTGTTCGGGGTGGTATGAGAACGCGGCGTTGTTGACCCGAAGCAGTTCGGCGTCATCGGTCGGGCCGGCGTAGGTGCGGATCCGCAGCCCGTCGGGGATTGTCGGCTCGGGGATATCGCGCAACGAGCGGCGCATCTGCACCAGTTCGCGCACCGGGGCCAGACCCAGCGCGGCGGCCGTGGCCCGGGCGGCTTCCAGGGTGCCGTGCGCCCAGAATTGGTTTTTCCCATGGGTTTTTGTCAGCGCGGCGCGCGCCATGGCGGTGCCGACACCGCGACGCCGGGATTGCGGGTGCACGACCAACTCGGCCATTGCGGAATCGGCATCGCGCGCCGGGCTGAGGTTGAGATAGCCGACGATCGCGTTGCCCGCTCGGGGATCAGTGGCCACCAGATGGTGCGTGCGCCGCTGTCCCAATTCTCGCAGCACCTGCTCGCCCACCGGCGCCACACCGTCGAATTCTGTTGCCGCCGAGATTATTTCGTGTACTTCCTGCTGCTGACCGGCTGTCAGCGCCGAGCGCCACTCCCCCGGCGTCACTGACTGCGCAGCGGGTCGACCAGCGGGTCCTGGAAATCTGCGGAATCGGGCCCCGATCCTTCGTCGTCGGGCTCGGCGACTGCGGTTCGGCCCCGCGCAGGCCGCACCGCCTTGTAACCGACGTTGCGGACGGTGCCGATCAGGGCTTCGTGCTCGGGGCCGAGTTTGGCGCGCAATCGCCGGACGTGCACATCGACCGTGCGGGTGCCGCCGAAGAAGTCGTATCCCCATACCTCGTGGAGTAGCTGCGCACGCGTGAACACCCGTCCGGCATGCTGGGCGAGGTATTTCAGGAGTTCGAATTCCTTGTAGGTGAGGTCGAGCGGTCGGCCCCGCAGTCGCGCGGTGTAGGTGCCTTCGTCGATCACCAGTTCCCCCAGGCTGACCTTGCCGACGCCTTCTTGGTCGGACAGACCGCCTCGCCGGCCAACCACCAGGCGCAGTCGGGCGTCGATCTCGGCCGGGCCGGTACTGGGCAGCAGGATCTCGTCCAGCCCCCAGTCAGCGCTGACTGCCACCAGCCCGCCCTCGGTCACCACGGCCAATACCGGCGCGGACCGACCCGCGGTGCTCAGCAGACGGCACAGACCGCGCGCGGCCGACAGGTCGTTGCGCGCGTCGACAAGCACCGCATCCGCGTTACCGGCCTCCAGCAGCGACGAAGCCTCCGGCGGCGCCGTCCGCACGTTATGCGAAAGCAGCGACAGCGACGGCAGGACTGGGTCGGGATACAGCTCCGAGGTCAGTAGTAGTAATTCCAACGATCCCCTCCAGCGTCGGGGGAAGGCATCTCCCTGAGTCAGCGCAACCGGTGAACTTTAGCGGCCGGATCGTCTAACGATAACCTGCCACCTGGTCTTTGGCCCGGTGACAATGCAGGCACCGCCTGCTGAGGAGCCGGGCAAATCCGACGACAGCCCGGTGACAATGCAGGCACCGCCTGCTGAGGAGCCGGGCAAATCCGACGACAGCCCGGTGACGATGCAGGCACCGCCTGCTGAGGAGCCGGGCAAATCCGACGACAGCCCGGTGACGATGCAGGCACCGCCTGCTGAGGAGCCGGGCAATCGACGACAGCCCGGTGACGATGCAGGCACCGCCTGCTGAGGAGCCGGGCAAATCCGACGACAGCCCGGTGACGATGCAGGCACCGCCTGCTGAGGAGCCGGGCAATCGACGACGCGGCCTGCGAAGTTGGCACCGGGCGCCGCGTCATGTCACATTCGCCCCATCTGCCCCAGCCGGTGCGGGGGATCTGCGTGTGTGCCCAGGTCACGAGAAAATTCAATCGTTGACCAGCACCTAGGAAACCCACGAAACCTTGGCCCAATTTTCGGCACGCCGATACGGCACCTCCGCTCGAACCTCTTGTGAGGGCGGGCGTTCGGGAGATACCTCACGTACTCACTGAATCGGCGGCCATGCCGCCGTATCGAGTGTGCGGTGACGGCTTTGAGGGTGCATGCAGGGCGGGGTCTGCCCACGATCGGCCGCCCTGACGGCACACTCGGCGCCATCAGCGCACAGTCGGCGCCATCAGCGCACAGTCGACGCCGCCAGCGCACAGTCGACGCCGCCAGCGCACAGTCGACGCCGCCAGCCGTCGACCCAACCGCACCAGCCCACGACCTTCATCTCTTCACGCCGGGGTGTGGCGCCCGCATCGCTCGCAGCGACAACGGGTGCGCAGCCGAGCGCGGCGGTTGTCGCTCCAAGCCGGGCACTCTTGGTGAGTCAGCGCGTACCGGCGGATCCGGAGGCACATGTGGCAGCTATGTCGGCGGCACTTGGAAACCCCGGCGCTGCAGCCGGCTTCAACCGCAGCTTCGGACCTGCCGCCAGCGGGTCAAGATTCAGATCCGGCCATGAAACGCCGTGGACGGCGACGCCCGGGAGCTCAGCCAGGGATAGCGCCGGGGCGATAGGCCACAATATGCGGATGCGCAAGGTGCTGATCGGTGTCGCCGCCGTGGCCGTCGTCGTCCTCGGCGCCGTCGGCGTCGACTTCGGCGCCAGCATTTACGCCGAATATCGGCTTTCGACCAGTGTGCGCAAGGCAGCCAACCTGGGCTCTGATCCCTTCGTCGCCATCCTCGGTTTTCCGTTCATCCCGCAGGCGATGCGAGATCGCTACGGCGAGCTGGAGATCAAGGCGTACGCCATCGAGCACTCGACGGTGGGCACAGCCACGCTCGAAGCCACCATGCATTCCATCGATCTGTCTCACGCATCCTGGCTGATACAGCCCGACGCGAGGTTGTCGGTGCACGAGCTGGAAAGCCGCATCATCATCGACTCCATGCACCTGGGCCGTTATCTGGGGATGGCCGATCTGATGGTGCAGGCGCCTCTCCAGGAAAGCAACGATGCCACCGGCGGCACCACCGAATCGGGGATATCGGGCAGTCACGGGCTCGTTTTCAGCGGGACACCGAAGTCAGCCGACTTCGATCGTCGGGTCAGCGTCGCGGTGGATCTGTCCATCGATCCCCACAGCCAGGAGACCTTGGTGATCACACCGACAGGGGTGGTGACCGGCCCGGACACCGCGGACCAGCCCGTTCCGGACGACAAACGGGAGGCGGTACTGCACGCCTTCAGTAGCAGGCTGCCCAACCAGAAGCTGCCGTTCGGGGTGGCGCCGAACACTGTGGGCGCACGCGGGTCGGACGTCATCATCGAGGGCATCACCTACGACGTGACCGTTGCGCTCACCGGATTCAGGCAGTCATGATCACCGGATCGACGCCCCACGGAAGCTCAACGCCGGCCGCCCCGGCCCCGACGATGCTGTTGGCTTGATCACTACGTCATTGGGTAAGCTGACCGACGTGTCAGCCCGCCTTGAGCTCAAGCTCACCAAGCGACGCGCAGTTGATCTGTGCCGCACCACGGGCTGTTGCTGTTGCTGTTGCTGTAGCTGCTGAGTAGCCGCGTCGTCCACGCAGCGCTCGGAGCAGCCTCGGAGACCCACCGCGGCGTATCTCCCACCTTTTCCGTGCAATCGGCGTATCTAGGAGTAATTCGTGTCGAGTAATAGCACCCCCGCCCAAGTGGGTGTCGACGTCCGCGGGCCGCGATTCGCCGCGTGGCTGACGACGGGGGTTCTGGGGCTCGTCCTGATCGTTTCCGCCTTCAGTTCGGCAGCTGCCGCAGTTGCCTTGAGCATCCAGGCGGTCGTGTTCGCTGTCGGTGCCGCATTCGGGCCTCGCCGGCATCCCTATGGGCTGCTGTACTCGACGTTTGTGTCGCCCCGCCTGGGACCGGTGCGAGAACGGGAACCTGCGCCACCGCTGAAGTTCGCCCAACTGGTCGGATTTGTGTTCGCTATCTGCGGGATCATCGGCTTCGCTGTCGGCCCGGTTGTGGTGGGCGTCGTTGCGACTTCGTTCGCGCTGGCGGCCGCCCTCCTCAACGCGGCCTTCGGCATCTGCCTGGGCTGCCAGCTTTACCCGCTGCTGGCCCGCCTGCGGCGCGGCGCCATTCCCGCCTGACTGCTGTTTATCTGACGCAAATCGAAAGGATCCCCACCATGGCACGCTCCGACGTCCTGGTCTCTGCCGACTGGGCTGAGAGCAATCTCAGCAATCCGGAAGCGGCCAACATCGTCTTCGTCGAAGTCGACGAGGACACCAGCGCATACGACGACGGCCACATCCCCGGCGCCATCAAGCTGGACTGGCGCACCGATCTGCAGGACCCGGTCAAACGCGACTTCGTCGACGCCCAGCAATTCTCGAAATTGCTCAGCGACCGCGGCATCTCCAACGACGACACCGTGGTCCTCTACGGCGGCAACAACAACTGGTTCGCCGCCTACGCCTACTGGTATTTCAAGCTGTACGGCCACGAGAAGGTCAAGCTGCTCGACGGCGGCCGCAAGAAGTGGGAACTCGACGGCCGCCCGCTGTCCACCGACACCGTCACCAGGCCCGCGACCTCCTACAGCGCGGCCCCGCCGGACAATGCCATCCGTGCATTCCGTGACGAGGTGATCGCGGCCATCGGCGCCAAGAACCTGGTCGACGTGCGATCCCCCGACGAGTTCTCCGGAAAGATCCTGGCGCCGGCGCATTTGCCGCAGGAACAGAGCCAGCGGCCCGGCCATATTCCCGGGGCGATCAACGTGCCGTGGAGCAAGGCCGCCAACGAGGACGGCACCTTCAAGTCCGACGAGCAACTGGCCCAGTTGTACGCCGGCGCCGGTCTGGACGGCACCAAGGAAACGATCGCGTACTGCCGGATCGGGGAACGGTCCTCGCACACCTGGTTTGTCTTGCACGAATTGCTCGGGCACAAGAACGTCAAGAACTACGACGGCAGTTGGACGGAATACGGCTCCCTGGTGGGTGCCCCGATCGAGTTGGGAAACTGATATGTGCACTGCGCCGAAGCAAGGACTGACGCTGCCTGCCAGTGTCGACCTGGAGAAGGAAACAGTGATCACCGGTCGTGTCGTGGACCGCGACGGCCAAGCCGTGGGCGGCGCCTTCGTCCGGCTGCTGGACTCGTCCGACGAGTTCACGGCGGAGGTGGTCGCGTCGGCCACCGGCGACTTCCGGTTCTTCGCCGCGCCGGGCTCCTGGACGGTGCGCGCACTGTCGAAAGTCGGCAATGGTGACGCGGTGGTCAGACCGTCGGGCGCGGGCATTCACGAGGTCGACGTCAAGATCGCCTGACAGCCGCTCCAGGCTGATCCCGGATAGACTCATCCGCGTGGTGCTGTTCTTCGAGATCATGCTGGTCCTGGCGACCGTGGTCATCTCCTGGTTCGCGCTGTATGCGCTGTATCGGCTGATCACCGACGAATCGTGACCTCCGACGACGGCCATCACGGGCCGGGTGCGGGCTCCGGCGACCGCGCCGTCGCCGGAATGTTTCAAGCGGCGGAACGTGCCAAGCTGACCGCGACCCGCAATATTCCCGTCTTCGACGATTTGCCACTACCCGCCGACACCGCCAACCTGCGCCAAGGCGCCAGCTTGCACGACGCGCTGCTGGCACTGCTGCCGCTGGTCGGTGTGTGGCGCGGCGAGGGAGAGGGCCGCGGACACGACGGTGACTACCGCTTCGGCCAGCAGATCGTCGTGTCGCACGACGGCGGAGACTATTTGAATTGGGAAGCCCGGTCGTGGCGTCTCACCGACACCGGTGAGTACCTCGAACCGGGTTTACGCGAGACGGGCTTCTGGCGTTTTGTCAGCGATCCCGACGACCCGAGCGAGTCGCAGGCGATCGAGCTGCTACTGGCGCACTCCGCCGGTTACGTCGAGTTGTTCTACGGCCGCCCGCGCAACCAGTCGTCCTGGGAGTTGGTCACCGACGCGTTGGCCCGGAGCCGCTCCGGCGTGCTGGTCGGCGGGGCCAAGCGGCTCTACGGCATCGTCGAGGGCGGCGACCTCGCCTATGTCGAGGAGCGGGTGGACGCCGACGGCGGGTTGGTGCCGCATCTGTCGGCGCGCTTGTCCAGATTCGTCGGCTGAGAGTTGCCCCCCGGGCCTGAGCCGCCCGAAGCTAACCGACCCATTTGTTGCCTTCGCCCGCTGGTTCTGCGTGTACTGTTCGACGTCCGAGCAGCCGATACACGAACGAAAGGAGCCGGCGGATGGCGCGCAGCAGGACACCCTCGCCGGTGGCTCGCTGGGTGGTGTCGGTCATCGGGGTGCTGTTGATCGCCTATCTCGCCGCGGTAGCCCTGCAACCAGCGATTCTCGATGTGCTGCCGTCCTGGCTGAGCTGGTTCGGCCGCCCGGGGTCGATGGCGACCATCGCGGTCGTGGTGTCGGTTTTGATCGCTGTCTCGGTGCTGAACTTCCGGGGAAACGGCAGCCACCGGCTGGTGGGTGTTTCGTTCACCGTGATTGCATTGCTCATCACGATGAGCGCCGTGTTGGGCCTCAGTTCGTACTGGGGCTGTCATGACGCCAACCATCCGGCTGTCTTCACCCCGTTGATGTGGACCGCCCAACTGGTCAAAGGCAGCACCGGGGACACCTCGCTGAGTGGGCGCACCTGCCCCAATCCCACGCCTGTCGGCCTGGAACTGGCCCGCATCGCGGCGCTGTCGGCGATCTTCACCGGCTTGGGCGGCGTCGTGGTCGGTGTCTTCCGCTCCCAGGTGGACCGGCTGCGGGCCAATCTCGCCGATTCGGTCACCGCGATCGTGGGTGTCGACGACGACACCGAATCGATGGTCAGCGCGATCGCGCGGACGTTGGATCGGCGCAGCACCCTGGTGGTGATCACCAACGCCGGCGACGACCGGGTGCAGCGGGTCCGAAGGCTGGGCGCCCGGGTGGTGCTGGTCGACCTCAACGCCCCGTCCACCCTGGTGTCGCTGCGACTGTGGCGCCATCTCGGGCGGCTCTATCTGATGTCGCCCGATCCGGCGACCAACCTGATGTGGCTGGACCTGATCGGTCGTCGGCTCGCCGAGATCGGCGACAAGCAGCGGTTGCCGCTCATCGTTCGCATCGACGACCCGTGGCTGGCCGAGGCGTGGCGGGCCCAGCAGTTCGGCGGCTCCGACACCAGATGGGCCGCCGACGTCGTCGGCCGGTACGAGGTCACCGCCGGCCGACTACTCGACGGCATCATCGCGACGCCCAACATACAACGCGTATTTATCTGCGGCACTTCACAATTGACGCTGGCACTGTGCGCCGACCTGACCCGGCGAGCGCTCGAACGCGACTTCTACACCCCGCCCGGGGTGCCACCTCTCCCGGCGCTCACGCTGGTGGAACGAGACGCCGAGGACTACCTCAAAGACCACCAGTTCTACCGCCAGCAGGCCGGCTTCTTGTCGGACGGACCGGCAATCGACGCGGTGCCCGAGGCGCCGACGGTACCGACCCTGCTGCGTCTCATCGGTGACGCCGACCCGGCAACGTGCGCAGTGATTCTGGTCGACACACATTCCGCGGCCACCGGAACCAGGCTGGGCGCGCGCCTGCCCGCGATGCCCGTCTACGCCTGGGACCCCAATGCCCGGGGCACCGAGGATTCCTCGCAGATCGTCGGCCTGCTGCAGACCTACAGCCTGGCGCTGGACACCCGTCAGGGTCAGGTACAGGACGCCTGGGAACGCGCGGCCAGGCTGATCCACGAGCGCTATGTCGCCACCATCGACCCGAACGCGCCGAGATCCCCGGCGGTGATGCCGTGGGCCCAACTCGACGAGTTCTACCGCGGGTCCAACCGTCGCCAGGTGCGCAACGCGCTATGGATGGTCGAACGGATCGCCGGACACACCTGGAACACCTGGGGCAGCCCGCCGGCCCAGCTGTCCGGCCGGGACATGGCCGATCTGCCGCCGCTAGAACAGCTCGCCCTGATGGGCTTCGACCGCTACTCGGCGCTGAGCATGGCCAAGGCAGAACATGAGGACTGGTGTCGCTACTACCGTCGCAACGGCTGGAAATACGGAACCCCCCGCGACGATTCCCGCCGAATCCACGACAAGCTGGTCGACTGGTCGGAGGTGGAAAGCAACCCCGACCTGCTCAACGCCGCGGTGCGCAGCCTGGCGGCCACCCTCTGGAGCCTGCGCCAGCTGGGCTACCGGTCACGCCCGCTGTGGCGATCTTTCACTCGTGTCGGGACGGTCACCGCTGAGCAGCGGGGCAGCCCGTGGACCTGGAAGTCGGATTCGGGACAGACCATGCGCGCGGCCGCGGGAGACTGGGCCGTCCAAGCCGACGGTAAGACCTGGTCGGTGCGCGACGACATCTTCCGGGCCACCTATGAGGACGTCGGCGACGGACAATGGCGCAGGAAGGGGCAGGTGCAGGGTCGGCCCGCGCATGCGGGCGAGACGATCAACACCCTGGAAGGGCCGACGATCGCCGCGGACGGAGACTGGGTGGTACGCGGCAGTGACGGCGAGCAATGGCCAGTCCCGGGGGACGAGTTCGCCCGCCGCTATGTCGAACTTCGTCCGCCGGAGGAAGAGGACGCCCACGAGGGACCGGATAGTAGTACCCATCGGCGCCAACCGGCGTCATGATGCAGCGCACGTTTGCCAAAGCCAGATTGCTGTGCTCAATGCCATGCGCTACCGTCGCTTGACGGATTCGCCGTGTTAGCTCCCCGCGCCCCCTCAATCGGAGACTGCTATGGCCATATTTATCAGCTACTCGAGCCAAGACCGGTCGTCGCTGGAAGCCCTGACGGCGGCGCTTCGGCGTGCCCAGCAGCAAGTTTGGTTCGATCAAGAGCTCGGCGGCGGCGACGCTTGGTGGAACAAGATACTGGAGCAGATTCGCGCATCCGACGTGTTCATCGTCGCGCTGTCGAATCACTGGCTGCAGTCCAAGCCCAGTCAGGCCGAGTTGCGCTACGCCCAAGCCCTGCAGCGGCCAATCCTTCCGGTACAGGTCGGGCCCGTCGACAGTGTGCGGGTAAATCCCGTCTCGACATTGCAGATCATCAACTACCAGAACCCGACCGTTGATGCCGGCATTCAATTGGTGACGGCAATACACGCGTTGCGCGAAAAGGCCCCGGCGCTGCCGTCGCCGCTGCCCGAGGAGCCACCTGTACCGTTCGGCTACCTGATGCGGCTCGGCGACACCCTGGCCGAAAAGGAACTCAGTCCCCAGCAACAGCTTCAGCTGCTGGTGGAGCTGCGATCCGGGCTCGACGAGGACGGCGACGATCCGAGCGCTCGCAGCGACATCGCCCAGCTGCTGCGCATGCTGCGGATGCGACACGACGTCACGTACCGCACCCGCACCGAAATCGACAATGTGCTCGCTGAAATCGGCGCCGTCGAAGCGGGTCCGGCCGGTGCATCGTCAACACCGCAAGCCAAACCGCAACCGAGTCCGGTGCCGGCAGCCGAGGCGGCGTCCGCGCCCAGCACCCAGTCTCGGCCGTCACCGGCGCAAGTCGCGCCAAGCGGTGCCAATGGCCAGTCGAACAAGCGGCTGCTCGTCATCGGCGGCGCCGTCGTGGCCGTCGTCGTCGCGGTCGCGTTGATTGCGGTGTTCGCCACCCAGGGAGGCAACCGGAAACCGGCGGCCAGGCCGGGCAGCTCCACGGCTCCGGCTGCTCCGGCGGCCGCATCCCGCATCGAACCGATGCTGCTCGGCGCCGCAGAAGTCGGACAGATTCTCGGCGACCAGAACATGATGGTCTCTGCGCACGGCGATCAACTGCGCGCCCCGCAGGGGACGCTGTCGGAACCGGCATGTCTGGCGGCCTACGAGCCCTTCCAGGAGTCGGTGTATCGGCCCCATGCCCCTACCGAGGTGCGCAGCCAGGTCCTGCACACCCAAGGCGAGAACCCGGCGCACCGAGTGATCGAAGCCGCAGCAACCTTCCCGTCGGCCGAGAAGGCTCGGGCATTCGTCCAGGCATCCGCAGACAAATGGGCGACCTGCGCGAACCAGACCGTCAAGTTCACCAGTTCGACCAAAGCCAGCGAATGGACCTTCGGGGATGTGACCGGGGCTTCCCCTAAAATTGCCCAGGTACGCACTGAGACCAACGGCAGCGGGAAGGCCTGCCAGCATGTGCTGAGGGCGGTATCGGATGTCGTCATCGAGGTGGAGGCCTGCGGTACGGACATCGCTGACGGAGCCGGCCAGATCGCGGAACAGATGAGTACCAAAGCGGCGAAGTAACACCGGCTACATATGGAGCGGCCCCCGAGCGCTTTTCCGGTTGGACAGACCGGAAGCTCGAGGGCCGGGTGGCTACGTGGGATTCGCCAGCGTGCGTAGAACGCCGGCTCTTCCGAGCCATTGCAGCTAGCGCGCAGCCACCTCACATGTCCATGAAGCTATCAATTTCGCGGACCACCTCCTTTCCTGTGTGTCTCGACCATAGCATTCAGGTCCCTTCCCGCACGTCGGCGACCGTTTTCGGGCTGACTAGAGTACGACCGCGGTACGGCGCCGGTACGCCTACAAATTGCCCGCTGTCGCCGGGGTAACGCCGGGGCGACGCCCAGGGTCAGTTAGGGCGTCGGAGCGACTCGCTAGTTTGCACGGCATCCTGACACCCCCAACCCCGACGCTCGTGTGAGAATGCCGCCGCCGATGTCCCCCTACTTCGTTTCAGGGGGCTGGCTGGGGAACGGGTGGTATCGCCGGATCGGGTGCTCGCGGTAAAAGATGCGATGCACGGTCATGCAGTGAGGTCAAGTCCAGGGACGTGGTGTACGACGTCGATCGTGTGATTCTTCGATTTTGTGATTTAGGCGGTCAGTGCTGTGGGGGTGTTCTCCTGTTCTGTCGGTGTGGTGGTGGTCGGGCGGGATTTGCTGAGGACGTCGAGGCCGAGGTAGCGGCGTGATTCGGCCCATTCATCGTGTTGTTCGGCCAGCACGGCGCCGACTAGGCGGATCAGGGCGTCACGGTCGGGGAAGATGCCGACAACGTCGGTGCGACGCCGAATTTCCTTGTTGAGCCGCTCTTTTATCCGGCCCTCAGGGTGGAGGTCAACCCGGTGTGGGTTCGGCTTCAACGATCGAGGCGTTGGAGATGGTCGGTGAGGGCATGGGCTACGCGGTCGTGGCGGGCTGCTTCGTCGGTCCAGCCGCGGTTCTCCGCGTCGGATTTGAGGGCTTGGACGTCGGCGAGTTGGTTAGTGAGGGCGCCGCGGAATTCGGGCGCGGTGATGTAGTTGTCGCAGGTTTCGCAGATGTTGGCATATGGGCAGGCGCCGGCGGTTGGGTGGCGCGCGCAGTAGCCGTGCCCGACACGGGTTTTCAGCATCTCACTGTGTAGCCAGCTGACCTTGTCGGGCAAGATGGGTCGACCGACCGGGGTGAGAGTGAACTGGCGACGCATCTTGCCCATGGCGTCGTCGTAGGCGGCGCGCAGGGTTGGCGAGGCAAGGGTGGCGTAGCGGATCGTCATCTGCGGTGTGACATGTCCGAGCAGCGCCATCAACGCTTGCATACTCATTCCGGCGTTGGCGAGTTCGGTGGCCCAGGTATGACGCAGCTGATGAGGCGTGACGACGAGGATGCCGCCGTCGGGTCCGCGTAGCCCTGAGGATTGGGCCGCGGCCAGCAGCCCGTTGCGCAGTCGGGTGTAGCCCAGGCGGCGGCCGTACTGGGTGAACAGGAAGTCGGTGAGCACGCCGGTGCGTGGATGGGCCAGTGGCCGGTGTGCGTCACGGTGGGTGACCCATTCGTCGAGCGCAGCGGTAGTGGCCGCCGATAGCGGCACCATGCGTTCGGTAGCCAGCTTGCCCAGCGGTACCTTTAGCCAGGTGCCAGCCGCCCCGTAGTCGATGATGCTGCCCAGTTCCAGGTCGAGCAGCTCACCCACCCGCAGCCCCGCTCCGCGCAGCACGGTCAGCCCGATACGAGCGAATGAATCATCTAGACGGGCAACAGCATTCATCACCGCCGCATCGATGTCAGGGGCCAGTGCCCGCGGCAGCGGCTGGTCAAGCTTGGGAACGTCGGCGGCGAAGACCAGTCGCCGCGGCGGTGCTTCTTCCCAGCCCCAGGCGGTGATGTCATCGAGCAGGTTGCGCAGGCTTAGCACCGCCGACTGGGCAACCGCAGCCGAGACGGTGCGCCCGGCGCCGGCGGCGGCACGTTGCCCGCGCCAGCCGCGGGTGCGGTTCCAGGTCAGATAGTCCTCGATGCAGGCGCGGTCGAGCTCGCGCAGGCTGGTCAGCTTCGAGTGGTGGGCGGTGAGGTATTCGACGAACGGCAGCAGGTCATTGATCAGCGATTCCACCGATTTGGGCCGCAACACCGCGGCTCGGACCCGGATATAGCGCAGCAGGGTGTCGAGGATCGGGGCAGCCATAGCCACGTCGGTGAAACGTTGCTCGAGGCTGCGTGCCCACGGTCGTCGTCGCGGAGCGGCGTCGAGGACCCGGACCTCGTAGAGCAGCTGGCGCAAGCTGGCCAACCGCGCCCGGTAGGCGCGCCGTGACGATCGCGGGATTGAACTCGCCGACAACGCACTGTCGAATTCATCGATCGCCTGCTCGGTGAGGTCAGCGACCAGCCCACCATGGCAAGCCACCAGCACCGCCAAGCACTCGCCGAGCACAGTTTCAATCCAGGAACTGCTCCAGCCCAACCGGTTTCCCGCTTCACGCATCGCGGAGAACCCGGCCGAATCACGCATCTCCACCGCGGCACCGAGCCCGGTCAGCTGCTTAATGACGGCCAGCTCAACATCCAGCCGCAACCGGCCGGCACCGATCGCATAGCACAGCAGGGGCCATGCCCCACTCGACCGAAGCTCGCCAGCCCGCTCAACCGCCGGCAGAGCCATCCACGCCGCCAGATCCGGGTGACGAGCAAGAAATTCCCGTGCGGTTCGGATCCGGTCCCGAATCGCCCGATCACTCAAGCGCAGGCGAGCGACGTGGTCGAGGTAGTCACTCAACAAAGTGCCGGCGTCAATGGAGTCCTGAACCGTAGCGACGGTCATCGCCGTGCTCCGGCCAAGGAGGCGCGGGCGGCACCATATTCGGCGGCGAGCTGCTCCAGTGACAGGTGCACGTAGCGGGCCGTGGTCTCCGGTGAGGCGTGTCCCATCAACGCCCGTAATGCAAGCAGATCAATTCCCGCAGAAGCCAATTCGGTACCATAGGTATGGCGCAGCCGATGCGGACGCACCCGGATGGACCCGGAGAGTTCACGGTGACGGCGAAACAAGCTGCGCAGCCCTGCCTCACTAACCGGCGCCCCCGTCGTCGGACCGCGCAGCACCACGAAGCACTGCGGTGTCGACAGCCCAGCCGGGCGCTCCAACCGCAGATAGGCAGCAACCTCAGTGAAGAATGCCGCATCGACCGGCACGTAGCGTTCCTTGCCGCCCTTGCCGATCACCCGCAGCCGCCGCCGCCCCATGTCCACATCGGCCAGCAGCAGACCGCGCGCTTCCGCCGACCGCAACCCGCCCAGCAGCATCGCCAGCACCATGGCCCGATCCCGATGTGACCCCAGCGTTGCGACAAATGCATCGATGTCGCTGGCCGGCAACGATTCCGGAAGCAGCTGCGGTTGGCGCACCAACCTGCCGCCAGGACGGGCACGCCCAGGACCCAGATGACCTAGCAGGCCGCGCTCCGAGCGGCGCAGCCCTTGCCCACGCCGCGGCGACGGGACCGGGTTGTTCCCACGGCGACCGGTCATCGCCAGGTACTCGAACAAGGCGCGTACCGCCGCCACCCGACGGTTCACCGTCGAGGCTGCAGCTGAGCCCGGCTGGGGCCGACCGGTGCGGCGTACCCCTTGCCAATCGATCCAGTCGAATACCAGTGGAGCCTGCACTTCGGACAGCGTCACATCGCGCTCAGTGAGGAACCGCGCCAGATTCGCCACGTCGAAGGCATACGCCCGAACCGTCGCCGCGCTAAATCCCCGTCCGGCCAAATGCGTGAGAAACGCATTGGCCGAATCCAACCCCTCCCAATCCCCACCGAGCCGATACCCCTCATCGACGCGCTGCACCCGCACCGTCATCACTCGACCTCCTGATCTCGGGGCCGCCCTCAGCATCTACCCGGCTCTGGGAACGGTCCCGGATCTCACGCCGCAGTCAGATTCGTGTCTCCTGAGGGCCGGTTAACGGATAGGGGGTTGTTGGACCAGATTTGGCGCCAGATCTGCTTGGGAAAAGCAGTGAACGCCAGCAAGTCCGATCGGGCGGCTTCGAGGTGATCGGCGACCTTGGGCAGCTTGTCGGCCAGGGCGTCGATGATCCGATCATATTGCGCAGCAACGGATGTGGCGTCGGGCTGATCGAACACCGAATGCAGCAGCGTCTTGACCCAGGGCCAGGAGCTCTTGGGGGTAATGGCCATCAAGTTGGTGGCGTAGTGGGTGCGACACCGCTGCCAGGATGCTCCGGGCAGGGTTGCCCCGATCGCGGAAAGCAACCCAGCATGGGCGTCACTGGTGACCAATGCCACCCCCGATAGGCCGCGGGCGGTCAACGAGCGCAGAAACGTCAACCAGCCGGCGCCGTCTTCGGCGGTGCTGACATCGATGCCTAAAATTTCGCGGTAACCCTCGGCGTTGACCCCCACCGCGATCAGCGCGTGCACGTTGACCACGCGGCCGGCCTCACGGACTTTAAGCACCAGGGCATCGGCGGCCATGAACGTGTACGGGCCAGCATCGAGGGGACGAGTCCGGAAGGCTTCCACGGCGGTGTCGAGCTCTTTGGCCATCACCGACACCTGCGACTTCGACAGGCCGGTGATCCCGAGAGTTTCGACGAGTTTGTCCATCCGCCGCGTGGACACCCCGAGCAGATAGCAGGTCGCCACCACGGTAGTCAGGGCCCGTTCGGCGCGTTTGCGGCGTTCCAGCAGCCAGTCCGGGAAGTAGGAGCCCTGGCGCAGCTTGGGGATCGCCAAATCCAAACTTCCTGCCCGGGTATCGAATTGGCGATGCCGGTAGCCGTTGCGGGAGTTGGTGCGCTCACTACTGCGTTGGCCATAGCCTGCGCCGCACAGCGCGTCGGCCTCGGCGCCCATCAGCGTGTGGATGAACGTGGCCAGCAGTTCGCGCAGCACATCAGGATGGGTGGTGGTGAGTCGTTCGGCCAGCACTGCAGGCAGGTCGATATCGTGGGCAGCGGTCATCGCGTCGATTCCTTTGCTTGAGTGACTTTGGACGGTCTCTCGAAGAATCACGCGATGACCCTCATCTACCCGGCTACGACACGCCGGTCCTCAACTCACGGCCCGACTCGTACACCACCTTGGTGGACGCAACCTGCAGTGAGTCCAGAGCATCTGTACAAGCGAGGGAAGTTCGTCAGCCAGAACAAAGCCTCGGCGCTCTAATGGTGACACCCTCTGGGCCCCGTCGTTGTTGCCGATATTGACGGCTGCCCAGCCATCCAGCACGAAGATTCCATCGGCCTGCTCGTGCCATGGGCTGTCTTTGAACTCGTCTCTTATGAGCTTGATCGCAGCTTCACCAGAGATGTTCGTTGTGTACGCGAAGATGAAAAAAGGAATGCGTTCGACGAATCGAGGGACATCCGTGGGTGCTGCGAAGACCTCACCGCCCTTGCCTGGGCGCCGATAGAGCTGCTTTACCGACCGCGCGTTCTTCATCGCTCGACGCAGTTCTTCGGTACTGAGCCGAGCCTTGACTTGGTATGCGGCTTCCACGGCGTGTGCAATCAACATCGATTGGCTGTCACCGGTCCAAAGTGGTTGAAACTCGTTGACGACCGCCACATCGACCTCGTCGGATTGACGGCCCTCGGGGTCGATGATGGATGAGCTGACAGCTACCCGGTGAGCCCCGAGGTTTTCTTTGAGAAAGTCCGCGAGTGCTCGCTCGTTCGCGCCACCTTTGATGTGGGAGTCCCTTTGCGTTTGGCGCGTTCGCTCGAAGTTTGCACGTAATTGGGCGGCACCTGTCGCCCAGAAGTCACTGATCGCATTCACGTGCCCCATTGTGATCCGATGGGCCGCACGACGGGCTACACCCCCTCCAGCGCTCCGTGCCCTCTTCCGCTACTTGCCGCACTTGCGTTTTGGCGCGGCGCTGCCCTTGGCGCGTCGCCTAATCGCCGACAGGGAATGCCCTACCCGGCAGCTTGGCGAGAAAAGTACGGGTTGATTCGTCGTAGGTCACAGGCGCACGCACCTGCCAAAACACGCTGGCGTCGGCATTAAACTCGACAGGAACACGAGTAATCATGGCGTACATACGAGCACACAACACGACCATCAAGCGCAAGGGCAAGGTGGTGAAGCGGTACGAGGTGGTGTGGCGCGAGCCCGCCTGCGACCCAACAACGGGCCTGCCCACCGGCAAGACCCGCGCCCGCCAGGAGAGCTGCCCAACCCGTGAGGCGGCTGAGGCGCGCCGCGACGAACTGAACAACGCCAAGCACCACCTCGGCGGCACAGCGGCTTTGGCCGACGCGAAGTGAAGGCGGCGCGGACGTTCGGCGACTACGCGGCGAAATGGCTGGCGGCGCAGCAGCTTAAGGTGGCCAACGGGCGGCTCAAGCAGGGCAGCTACGACAGCTATAGCGGCTGGCCTGACCCCGATCGGTTGGTCCATGGCTTATGAGAGTCTTGCAGCCCACGCTGTGGGCAGGAAGGCTCAACAAGATCATGGCAACAAGGAAGCGGCATAGCCCCGAGCAGATCGTGCGCAAGCTGACGCTGGCGGATCGGCTGTTGTCCGAGGGCAAGGACACAGCGGCAGTGTGCCGCGAGCTGGGTGTGTCGGAGGCGACGTATCACCGATGGCGCAATCAGTTCGGTGGTTTGAAGGCCGAGGATGCCAAGCGCCTGAAGGACCTCGAGCGCGAGAACGCAACGCTGAAGCGGCTCTTGGCAGATGCCGAGTTAGAGAAGGCTGCACTCAAGGAGATCGCGCGGGGAAACTTCTAGGCCCGGAGCGTCGGCGGGCAGCCGTTCGTCACCTCCAGCGTGTGCTGGGGGTCAGCGAACGGTTCGCCTGCCGCGTGACCGGGCAGCATCGGGCCACCCAACGCCACGAACCCGCCGCCGAGACTGCCCAGGACCCCGATGCCGGCTTGCGGGCCTGGCTGCGCCGCTACGCCAAAGACCATCCGCGGCGTGGGTTTCGGCCCGCTTATCACGATGCCCGCGCTGAAGGTTGGCAAGTCAATCACAAGAAGGTGCAACGGCTCTGGCGTGAGGAAGGCTTGCGCGTGCCGCAGCGGCGGCGCCGTAAACGACGCGGTAGCTCCACCGCCCGGCCCGAGGTATGCGCCGATGCCCCCAACCGGGTCTGGGCCGTGGACTTTCAGTTCGATTCCACTACCGATGGGCGCCCGTTCAAGATCGTCTCGATCATCGACGAGCACACCCGCGAATGTCTCGGCGACAAGGTAGACCGCAGCATCACCGGCGAGGACCTCATCGACGAACTTGACCGCATCGCCGCTCAACGCGGTACCTATCCGAACGTGCTCAGATGTGACAACGGACCCGAATTAGCCTGTGCGGCAATGGCAGACTGGGCCGACGGTCACGTCGGGCTGCACTTTATCCCGCCCGGTGAACCTTGGCGAAACGGCTACGTCGAATCATTTAACTCCCGCATCCGCGACGAATGCCTCAACATCAACAGCTTCTGGTCTCTAGCCCAGGCCCGCGTGGTCATCAGCGACTGGAAACATGACTACAACCATCACCGGCGGCACTCTGCCTTGGGCTACCAAGCCCCCGCCCACTACGCTGCCACCTGCACCCACCAATGAACGACTCTCGTTCGCCGTGGACCAGTTCACGGGGTCCGGTCACGGCTATCTGAGCCGATACGCGCTGAAATCGTTGGTTGCGTCCACCAAGGTGGTGTACGAGTCGGGCCGTGAGTTGAGGACCGGCGTGTCGTAGCCGGGTAGATGAGGGTCATCGCGTGATTCTTCGAGAGACCGTCCAAAGTCACTCAAGCAAAGGAATCGACGCGATGACCGCTGCCCACGATATCGACCTGCCTGCAGTGCTGGCCGAACGACTCACCACCACCCATCCTGATGTGCTGCGCGAACTGCTGGCCACGTTCATCCACACGCTGATGGGCGCCGAGGCCGACGCGCTGTGCGGCGCAGGCTATGGCCAACGCAGTAGTGAGCGCACCAACTCCCGCAACGGCTACCGGCATCGCCAATTCGATACCCGGGCAGGAAGTTTGGATTTGGCGATCCCCAAGCTGCGCCAGGGCTCCTACTTCCCGGACTGGCTGCTGGAACGCCGCAAACGCGCCGAACGGGCCCTGACTACCGTGGTGGCGACCTGCTATCTGCTCGGGGTGTCCACGCGGCGGATGGACAAACTCGTCGAAACTCTCGGGATCACCGGCCTGTCGAAGTCGCAGGTGTCGGTGATGGCCAAAGAGCTCGACACCGCCGTGGAAGCCTTCCGGACTCGTCCCCTCGATGCTGGCCCGTACACGTTCATGGCCGCCGATGCCCTGGTGCTTAAAGTCCGTGAGGCCGGCCGCGTGGTCAACGTGCACGCGCTGATCGCGGTGGGGGTCAACGCCGAGGGTTACCGCGAAATTTTAGGCATCGATGTCAGCACCGCCGAAGACGGCGCCGGCTGGTTGACGTTTCTGCGCTCGTTGACCGCCCGCGGCCTATCGGGGGTGGCATTGGTCACCAGTGACGCCCATGCTGGGTTGCTTTCCGCGATCGGGGCAACCCTGCCCGGAGCATCCTGGCAGCGGTGTCGCACCCACTACGCCACCAACTTGATGGCCATTACCCCCAAGAGCTCCTGGCCCTGGGTCAAGACGCTGCTGCATTCGGTGTTCGATCAGCCCGACGCCACATCCGTTGCTGCGCAATATGATCGGATCATCGACGCCCTGGCCGACAAGCTGCCCAAGGTCGCCGATCACCTCGAAGCCGCCCGATCGGACTTGCTGGCGTTCACTGCTTTTCCCAAGCAGATCTGGCGCCAAATCTGGTCCAACAACCCCCTATCCGTTAACCGGCCCTCAGGAGACACGAATCTGACTGCGGCGTGAGATCCGGGACCGTTCCCAGAGCCGGGTAGATGCTGAGGGCGGCCCCGAGATCAGGAGGTCGAGTGATGACGGTGCGGGTGCAGCGCGTCGATGAGGGGTATCGGCTCGGTGGGGATTGGGAGGGGTTGGATTCGGCCAATGCGTTTCTCACGCATTTGGCCGGACGGGGATTTAGCGCGGCGACGGTTCGGGCGTATGCCTTCGACGTGGCGAATCTGGCGCGGTTCCTCACTGAGCGCGATGTGACGCTGTCCGAAGTGCAGGCTCCACTGGTATTCGACTGGATCGATTGGCAAGGGGTACGCCGCACCGGTCGGCCCCAGCCGGGCTCAGCTGCAGCCTCGACGGTGAACCGTCGGGTGGCGGCGGTACGCGCCTTGTTCGAGTACCTGGCGATGACCGGTCGCCGTGGGAACAACCCGGTCCCGTCGCCGCGGCGTGGGCAAGGGCTGCGCCGCTCGGAGCGCGGCCTGCTAGGTCATCTGGGTCCTGGGCGTGCCCGTCCTGGCGGCAGGTTGGTGCGCCAACCGCAGCTGCTTCCGGAATCGTTGCCGGCCAGCGACATCGATGCATTTGTCGCAACGCTGGGGTCACATCGGGATCGGGCCATGGTGCTGGCGATGCTGCTGGGCGGGTTGCGGTCGGCGGAAGCGCGCGGTCTGCTGCTGGCCGATGTGGACATGGGGCGGCGGCGGCTGCGGGTGATCGGCAAGGGCGGCAAGGAACGCTACGTGCCGGTCGATGCGGCATTCTTCACTGAGGTTGCTGCCTATCTGCGGTTGGAGCGCCCGGCTGGGCTGTCGACACCGCAGTGCTTCGTGGTGCTGCGCGGTCCGACGACGGGGGCGCCGGTTAGTGAGGCAGGGCTGCGCAGCTTGTTTCGCCGTCACCGTGAACTCTCCGGGTCCATCCGGGTGCGTCCGCATCGGCTGCGCCATACCTATGGTACCGAATTGGCTTCTGCGGGAATTGATCTGCTTGCATTACGGGCGTTGATGGGACACGCCTCACCGGAGACCACGGCCCGCTACGTGCACCTGTCACTGGAGCAGCTCGCCGCCGAATATGGTGCCGCCCGCGCCTCCTTGGCCGGAGCACGGCGATGACCGTCGCTACGGTTCAGGACTCCATTGACGCCGGCACTTTGTTGAGTGACTACCTCGACCACGTCGCTCGCCTGCGCTTGAGTGATCGGGCGATTCGGGACCGGATCCGAACCGCACGGGAATTTCTTGCTCGTCACCCGGATCTGGCGGCGTGGATGGCTCTGCCGGCGGTTGAGCGGGCTGGCGAGCTTCGGTCGAGTGGGGCATGGCCCCTGCTGTGCTATGCGATCGGTGCCGGCCGGTTGCGGCTGGATGTTGAGCTGGCCGTCATTAAGCAGCTGACCGGGCTCGGTGCCGCGGTGGAGATGCGTGATTCGGCCGGGTTCTCCGCGATGCGTGAAGCGGGAAACCGGTTGGGCTGGAGCAGTTCCTGGATTGAAACTGTGCTCGGCGAGTGCTTGGCGGTGCTGGTGGCTTGCCATGGTGGGCTGGTCGCTGACCTCACCGAGCAGGCGATCGATGAATTCGACAGTGCGTTGTCGGCGAGTTCAATCCCGCGATCGTCACGGCGCGCCTACCGGGCGCGGTTGGCCAGCTTGCGCCAGCTGCTCTACGAGGTCCGGGTCCTCGACGCCGCTCCGCGACGACGACCGTGGGCACGCAGCCTCGAGCAACGTTTCACCGACGTGGCTATGGCTGCCCCGATCCTCGACACCCTGCTGCGCTATATCCGGGTCCGAGCCGCGGTGTTGCGGCCCAAATCGGTGGAATCGCTGATCAATGACCTGCTGCCGTTCGTCGAATACCTCACCGCCCACCACTCGAAGCTGACCAGCCTGCGCGAGCTCGACCGCGCCTGCATCGAGGACTATCTGACCTGGAACCGCACCCGCGGCTGGCGCGGGCAACGTGCCGCCGCCGGCGCCGGGCGCACCGTCTCGGCTGCGGTTGCCCAGTCGGCGGTGCTAAGCCTGCGCAACCTGCTCGATGACATCACCGCCTGGGGCTGGGAAGAAGCACCGCCGCGGCGACTGGTCTTCGCCGCCGACGTTCCCAAGCTTGACCAGCCGCTGCCGCGGGCACTGGCCCCTGACATCGATGCGGCGGTGATGAATGCTGTTGCCCGTCTAGATGATTCATTCGCTCGTATCGGGCTGACCGTGCTGCGCGGAGCGGGGCTGCGGGTGGGTGAGCTGCTCGACCTGGAACTGGGCAGCATCATCGACTACGGGGCGGCTGGCACCTGGCTAAAGGTACCGCTGGGCAAGCTGGCTACCGAACGCATGGTGCCGCTATCGGCGGCCACTACCGCTGCGCTCGACGAATGGGTCACCCACCGTGACGCACACCGGCCACTGGCCCATCCACGCACCGGCGTGCTCACCGACTTCCTGTTCACCCAGTACGGCCGCCGCCTGGGCTACACCCGACTGCGCAACGGGCTGCTGGCCGCGGCCCAATCCTCAGGGCTACGCGGACCCGACGGCGGCATCCTCGTCGTCACGCCTCATCAGCTGCGTCATACCTGGGCCACCGAACTCGCCAACGCCGGAATGAGTATGCAAGCGTTGATGGCGCTGCTCGGACATGTCACACCGCAGATGACGATCCGCTACGCCACCCTTGCCTCGCCAACCCTGCGCGCCGCCTACGACGACGCCATGGGCAAGATGCGTCGCCAGTTCACTCTCACCCCGGTCGGTCGACCCATCTTGCCCGACAAGGTCAGCTGGCTACACAGTGAGATGCTGAAAACCCGTGTCGGGCACGGCTACTGCGCGCGCCACCCAACCGCCGGCGCCTGCCCATATGCCAACATCTGCGAAACCTGCGACAACTACATCACCGCGCCCGAATTCCGCGGCGCCCTCACTAACCAACTCGCCGACGTCCAAGCCCTCAAATCCGACGCGGAGAACCGCGGCTGGACCGACGAAGCAGCCCGCCACGACCGCGTAGCCCATGCCCTCACCGACCATCTCCAACGCCTCGATCGTTGA

Protein sequences of DBSCAN-SWA_2

>NZ_CP009483|2361670:2392391|2385549_2386287_-|WP_023367992.1|DBSCAN-SWA
MGHVNAISDFWATGAAQLRANFERTRQTQRDSHIKGGANERALADFLKENLGAHRVAVSSSIIDPEGRQSDEVDVAVVNEFQPLWTGDSQSMLIAHAVEAAYQVKARLSTEELRRAMKNARSVKQLYRRPGKGGEVFAAPTDVPRFVERIPFFIFAYTTNISGEAAIKLIRDEFKDSPWHEQADGIFVLDGWAAVNIGNNDGAQRVSPLERRGFVLADELPSLVQMLWTHCRLRPPRWCTSRAVS
>NZ_CP009483|2361670:2392391|2378999_2380511_+|WP_023367989.1|DBSCAN-SWA
MAIFISYSSQDRSSLEALTAALRRAQQQVWFDQELGGGDAWWNKILEQIRASDVFIVALSNHWLQSKPSQAELRYAQALQRPILPVQVGPVDSVRVNPVSTLQIINYQNPTVDAGIQLVTAIHALREKAPALPSPLPEEPPVPFGYLMRLGDTLAEKELSPQQQLQLLVELRSGLDEDGDDPSARSDIAQLLRMLRMRHDVTYRTRTEIDNVLAEIGAVEAGPAGASSTPQAKPQPSPVPAAEAASAPSTQSRPSPAQVAPSGANGQSNKRLLVIGGAVVAVVVAVALIAVFATQGGNRKPAARPGSSTAPAAPAAASRIEPMLLGAAEVGQILGDQNMMVSAHGDQLRAPQGTLSEPACLAAYEPFQESVYRPHAPTEVRSQVLHTQGENPAHRVIEAAATFPSAEKARAFVQASADKWATCANQTVKFTSSTKASEWTFGDVTGASPKIAQVRTETNGSGKACQHVLRAVSDVVIEVEACGTDIADGAGQIAEQMSTKAAK
>NZ_CP009483|2361670:2392391|2367598_2368591_-|WP_080674221.1|DBSCAN-SWA
MVAAPFPEPPATSINPWGTGKPGLGDRVFRGLSQGSGVLIIVLIAAIGAFLLWRAIPALARNKENFLTYGGTWKTADPSAMHFGILDLLRVTTFVSLFALVLAMPVALGVAIFLTQYAPRRFAMPLAHLVDLLAAVPSIIYGVWGLHVLAPHLRPVATSLNHTLGHCFLFAGGNTSIGGGGNVFTGGIVLAVMILPIITAVTREVFAQTPHGQIEAALALGATRWEVVTTTVLPFGRSGYISGAMLGLGRALGETVALLIILHGTQQAFGWSLFDGGSTFATKIAAAASGLDNPYQAGAYLAAGLMLYLLTFVVNAAARAALAGAGRATR
>NZ_CP009483|2361670:2392391|2370878_2371643_-|WP_023367969.1|DBSCAN-SWA
MELLLLTSELYPDPVLPSLSLLSHNVRTAPPEASSLLEAGNADAVLVDARNDLSAARGLCRLLSTAGRSAPVLAVVTEGGLVAVSADWGLDEILLPSTGPAEIDARLRLVVGRRGGLSDQEGVGKVSLGELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLHEVWGYDFFGGTRTVDVHVRRLRAKLGPEHEALIGTVRNVGYKAVRPARGRTAVAEPDDEGSGPDSADFQDPLVDPLRSQ
>NZ_CP009483|2361670:2392391|2389416_2390451_+|WP_036393475.1|integrase|DBSCAN-SWA
MRVQRVDEGYRLGGDWEGLDSANAFLTHLAGRGFSAATVRAYAFDVANLARFLTERDVTLSEVQAPLVFDWIDWQGVRRTGRPQPGSAAASTVNRRVAAVRALFEYLAMTGRRGNNPVPSPRRGQGLRRSERGLLGHLGPGRARPGGRLVRQPQLLPESLPASDIDAFVATLGSHRDRAMVLAMLLGGLRSAEARGLLLADVDMGRRRLRVIGKGGKERYVPVDAAFFTEVAAYLRLERPAGLSTPQCFVVLRGPTTGAPVSEAGLRSLFRRHRELSGSIRVRPHRLRHTYGTELASAGIDLLALRALMGHASPETTARYVHLSLEQLAAEYGAARASLAGARR
>NZ_CP009483|2361670:2392391|2369940_2370882_-|WP_023367967.1|DBSCAN-SWA
MTPGEWRSALTAGQQQEVHEIISAATEFDGVAPVGEQVLRELGQRRTHHLVATDPRAGNAIVGYLNLSPARDADSAMAELVVHPQSRRRGVGTAMARAALTKTHGKNQFWAHGTLEAARATAAALGLAPVRELVQMRRSLRDIPEPTIPDGLRIRTYAGPTDDAELLRVNNAAFSYHPEQGGWTQQQLAERRGEPWFDPAGLILAFDASPGHEAKLLGFHWTKIHHQPDLGEVYVLGVDPVAQGRGLGKALTLIGLSSLARRLAGVNPAEEPTVMLYVESDNVAAMRTYHSLGFVTHSVDTAYALACSDPALG
>NZ_CP009483|2361670:2392391|2368697_2369822_-|WP_023367965.1|DBSCAN-SWA
MRLDTVVRAFAAAVAVITACGGTLTACGSDQNPGISSANGSAAPLPKADCSGRDALTAEGSTAQQNAMALFNQAWGQACPGKKVSYNPTGSGAGREQFIAGHVDFAGSDSPLVAEQIGPAADRCKGNPAWDLPLVFGPIALVYNLAGVTNLVLDADAMAKIFSGSIRTWNDPILAALNPGVALPNIKIIPVYRKDSSGTTDNFQKYLTAAAPQSWSRGVGGEFHGGVGEGVERSAGVIQAVQVTPGSIGYVEKGFADRAGIPFAQIDTGNNVVPLTEETARKAIDSVTFAANGNDLVLDLNSIFAIQDPGAYPLVLATYEIVCSKGYPRDIGAAVKAFLTTAVHNGQTGLPSAGYVPVPDKVEERLVTAINALQ
>NZ_CP009483|2361670:2392391|2371755_2371989_+|WP_023367971.1|DBSCAN-SWA
MQAPPAEEPGKSDDSPVTMQAPPAEEPGKSDDSPVTMQAPPAEEPGKSDDSPVTMQAPPAEEPGNRRQPGDDAGTAC
>NZ_CP009483|2361670:2392391|2388283_2389345_+|WP_023364744.1|transposase|DBSCAN-SWA
MTAAHDIDLPAVLAERLTTTHPDVLRELLATFIHTLMGAEADALCGAGYGQRSSERTNSRNGYRHRQFDTRAGSLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLLGVSTRRMDKLVETLGITGLSKSQVSVMAKELDTAVEAFRTRPLDAGPYTFMAADALVLKVREAGRVVNVHALIAVGVNAEGYREILGIDVSTAEDGAGWLTFLRSLTARGLSGVALVTSDAHAGLLSAIGATLPGASWQRCRTHYATNLMAITPKSSWPWVKTLLHSVFDQPDATSVAAQYDRIIDALADKLPKVADHLEAARSDLLAFTAFPKQIWRQIWSNNPLSVNRPSGDTNLTAA
>NZ_CP009483|2361670:2392391|2390447_2392391_+|WP_023364740.1|integrase|DBSCAN-SWA
MTVATVQDSIDAGTLLSDYLDHVARLRLSDRAIRDRIRTAREFLARHPDLAAWMALPAVERAGELRSSGAWPLLCYAIGAGRLRLDVELAVIKQLTGLGAAVEMRDSAGFSAMREAGNRLGWSSSWIETVLGECLAVLVACHGGLVADLTEQAIDEFDSALSASSIPRSSRRAYRARLASLRQLLYEVRVLDAAPRRRPWARSLEQRFTDVAMAAPILDTLLRYIRVRAAVLRPKSVESLINDLLPFVEYLTAHHSKLTSLRELDRACIEDYLTWNRTRGWRGQRAAAGAGRTVSAAVAQSAVLSLRNLLDDITAWGWEEAPPRRLVFAADVPKLDQPLPRALAPDIDAAVMNAVARLDDSFARIGLTVLRGAGLRVGELLDLELGSIIDYGAAGTWLKVPLGKLATERMVPLSAATTAALDEWVTHRDAHRPLAHPRTGVLTDFLFTQYGRRLGYTRLRNGLLAAAQSSGLRGPDGGILVVTPHQLRHTWATELANAGMSMQALMALLGHVTPQMTIRYATLASPTLRAAYDDAMGKMRRQFTLTPVGRPILPDKVSWLHSEMLKTRVGHGYCARHPTAGACPYANICETCDNYITAPEFRGALTNQLADVQALKSDAENRGWTDEAARHDRVAHALTDHLQRLDR
>NZ_CP009483|2361670:2392391|2375693_2376365_+|WP_023367983.1|DBSCAN-SWA
MTSDDGHHGPGAGSGDRAVAGMFQAAERAKLTATRNIPVFDDLPLPADTANLRQGASLHDALLALLPLVGVWRGEGEGRGHDGDYRFGQQIVVSHDGGDYLNWEARSWRLTDTGEYLEPGLRETGFWRFVSDPDDPSESQAIELLLAHSAGYVELFYGRPRNQSSWELVTDALARSRSGVLVGGAKRLYGIVEGGDLAYVEERVDADGGLVPHLSARLSRFVG
>NZ_CP009483|2361670:2392391|2375258_2375561_+|WP_023367979.1|DBSCAN-SWA
MCTAPKQGLTLPASVDLEKETVITGRVVDRDGQAVGGAFVRLLDSSDEFTAEVVASATGDFRFFAAPGSWTVRALSKVGNGDAVVRPSGAGIHEVDVKIA
>NZ_CP009483|2361670:2392391|2376487_2378890_+|WP_042312135.1|DBSCAN-SWA
MARSRTPSPVARWVVSVIGVLLIAYLAAVALQPAILDVLPSWLSWFGRPGSMATIAVVVSVLIAVSVLNFRGNGSHRLVGVSFTVIALLITMSAVLGLSSYWGCHDANHPAVFTPLMWTAQLVKGSTGDTSLSGRTCPNPTPVGLELARIAALSAIFTGLGGVVVGVFRSQVDRLRANLADSVTAIVGVDDDTESMVSAIARTLDRRSTLVVITNAGDDRVQRVRRLGARVVLVDLNAPSTLVSLRLWRHLGRLYLMSPDPATNLMWLDLIGRRLAEIGDKQRLPLIVRIDDPWLAEAWRAQQFGGSDTRWAADVVGRYEVTAGRLLDGIIATPNIQRVFICGTSQLTLALCADLTRRALERDFYTPPGVPPLPALTLVERDAEDYLKDHQFYRQQAGFLSDGPAIDAVPEAPTVPTLLRLIGDADPATCAVILVDTHSAATGTRLGARLPAMPVYAWDPNARGTEDSSQIVGLLQTYSLALDTRQGQVQDAWERAARLIHERYVATIDPNAPRSPAVMPWAQLDEFYRGSNRRQVRNALWMVERIAGHTWNTWGSPPAQLSGRDMADLPPLEQLALMGFDRYSALSMAKAEHEDWCRYYRRNGWKYGTPRDDSRRIHDKLVDWSEVESNPDLLNAAVRSLAATLWSLRQLGYRSRPLWRSFTRVGTVTAEQRGSPWTWKSDSGQTMRAAAGDWAVQADGKTWSVRDDIFRATYEDVGDGQWRRKGQVQGRPAHAGETINTLEGPTIAADGDWVVRGSDGEQWPVPGDEFARRYVELRPPEEEDAHEGPDSSTHRRQPAS
>NZ_CP009483|2361670:2392391|2381351_2383295_-|WP_023364740.1|integrase|DBSCAN-SWA
MTVATVQDSIDAGTLLSDYLDHVARLRLSDRAIRDRIRTAREFLARHPDLAAWMALPAVERAGELRSSGAWPLLCYAIGAGRLRLDVELAVIKQLTGLGAAVEMRDSAGFSAMREAGNRLGWSSSWIETVLGECLAVLVACHGGLVADLTEQAIDEFDSALSASSIPRSSRRAYRARLASLRQLLYEVRVLDAAPRRRPWARSLEQRFTDVAMAAPILDTLLRYIRVRAAVLRPKSVESLINDLLPFVEYLTAHHSKLTSLRELDRACIEDYLTWNRTRGWRGQRAAAGAGRTVSAAVAQSAVLSLRNLLDDITAWGWEEAPPRRLVFAADVPKLDQPLPRALAPDIDAAVMNAVARLDDSFARIGLTVLRGAGLRVGELLDLELGSIIDYGAAGTWLKVPLGKLATERMVPLSAATTAALDEWVTHRDAHRPLAHPRTGVLTDFLFTQYGRRLGYTRLRNGLLAAAQSSGLRGPDGGILVVTPHQLRHTWATELANAGMSMQALMALLGHVTPQMTIRYATLASPTLRAAYDDAMGKMRRQFTLTPVGRPILPDKVSWLHSEMLKTRVGHGYCARHPTAGACPYANICETCDNYITAPEFRGALTNQLADVQALKSDAENRGWTDEAARHDRVAHALTDHLQRLDR
>NZ_CP009483|2361670:2392391|2366687_2367602_-|WP_023367961.1|DBSCAN-SWA
MTSMLDRPVKARALPALGRRRRVTDNMAAVLVTLSMAIALTPLAWVLCSVLVNGLRTVLSSTWWTHSQAGMTSLKAGGGAYHAIVGTVLQGVVCAAISIPIGVLVAIYLVEYGGASALRRVVSFMVDILTGVPSIVAALFIYALWVAVLGFPRSQLAVSLALVLLMLPVIVRSTEEMLRIVPVDLREASYALGAPKWKTIAKIVIPTGLSGIVTGILLALARVMGETAPLLILVGYAQTMNFDIFSGFMGSLPGMMYDQATAGAGISPVPTERLWGAALTLMLLIAMINIGARVVAAILVPKKS
>NZ_CP009483|2361670:2392391|2373908_2374376_+|WP_036393799.1|DBSCAN-SWA
MSSNSTPAQVGVDVRGPRFAAWLTTGVLGLVLIVSAFSSAAAAVALSIQAVVFAVGAAFGPRRHPYGLLYSTFVSPRLGPVREREPAPPLKFAQLVGFVFAICGIIGFAVGPVVVGVVATSFALAAALLNAAFGICLGCQLYPLLARLRRGAIPA
>NZ_CP009483|2361670:2392391|2383291_2384326_-|WP_036393475.1|integrase|DBSCAN-SWA
MRVQRVDEGYRLGGDWEGLDSANAFLTHLAGRGFSAATVRAYAFDVANLARFLTERDVTLSEVQAPLVFDWIDWQGVRRTGRPQPGSAAASTVNRRVAAVRALFEYLAMTGRRGNNPVPSPRRGQGLRRSERGLLGHLGPGRARPGGRLVRQPQLLPESLPASDIDAFVATLGSHRDRAMVLAMLLGGLRSAEARGLLLADVDMGRRRLRVIGKGGKERYVPVDAAFFTEVAAYLRLERPAGLSTPQCFVVLRGPTTGAPVSEAGLRSLFRRHRELSGSIRVRPHRLRHTYGTELASAGIDLLALRALMGHASPETTARYVHLSLEQLAAEYGAARASLAGARR
>NZ_CP009483|2361670:2392391|2361670_2362861_+|WP_023367953.1|tRNA|DBSCAN-SWA
MRIGSIELASPVVLAPMAGVTNVAFRTLCRDFGSMRGDPLRPASPPLRSPREQAKVGTVGGLYVCEMVTARALVERHPVTMHMTTFAPDESPRSLQLYTVDPDTTYAAARMIADEGLADHIDMNFGCPVPKVTKRGGGAALPFKRRLFGRIVAAAVRAAEGTGIPVTVKFRIGIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWDQISRLKQQVTTIPVLGNGDIYDASDALAMMATTGCDGVVIGRGCLGRPWLFAELSAAFTGRPAPTPPTLGEVADVIRRHGALLAAHFGEDKGMRDIRKHIAWYLHGFPAGSDVRRALALVKTLSELDDLLNRLDGSVPFPSAGNGPRGRQGSPARVALPDGWLDDADDCRVPDGADVMHSGG
>NZ_CP009483|2361670:2392391|2365218_2365887_+|WP_023367957.1|DBSCAN-SWA
MRTAYHEQLSELSERLGEMCGLAGIAMERATQALLQADLVLAEQVISDHEKIATLSARAEESAFVLLALQAPVAGDLRAIVSAIQMVADIDRMGALALHVAKIARRRHPQHALPEEVKGYFAEMGRVAVELGNSAQEVVLSRDPEKAARIREEDDAMDDLHRHLFSVLMDREWKHGVAAAVDVTLLGRFYERFADHAVEVARRVIFQATGRFPEDETTPHSR
>NZ_CP009483|2361670:2392391|2386532_2386769_+|WP_023367994.1|DBSCAN-SWA
MAYIRAHNTTIKRKGKVVKRYEVVWREPACDPTTGLPTGKTRARQESCPTREAAEARRDELNNAKHHLGGTAALADAK
>NZ_CP009483|2361670:2392391|2374414_2375257_+|WP_023367977.1|DBSCAN-SWA
MARSDVLVSADWAESNLSNPEAANIVFVEVDEDTSAYDDGHIPGAIKLDWRTDLQDPVKRDFVDAQQFSKLLSDRGISNDDTVVLYGGNNNWFAAYAYWYFKLYGHEKVKLLDGGRKKWELDGRPLSTDTVTRPATSYSAAPPDNAIRAFRDEVIAAIGAKNLVDVRSPDEFSGKILAPAHLPQEQSQRPGHIPGAINVPWSKAANEDGTFKSDEQLAQLYAGAGLDGTKETIAYCRIGERSSHTWFVLHELLGHKNVKNYDGSWTEYGSLVGAPIELGN
>NZ_CP009483|2361670:2392391|2384397_2385459_-|WP_023364744.1|transposase|DBSCAN-SWA
MTAAHDIDLPAVLAERLTTTHPDVLRELLATFIHTLMGAEADALCGAGYGQRSSERTNSRNGYRHRQFDTRAGSLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLLGVSTRRMDKLVETLGITGLSKSQVSVMAKELDTAVEAFRTRPLDAGPYTFMAADALVLKVREAGRVVNVHALIAVGVNAEGYREILGIDVSTAEDGAGWLTFLRSLTARGLSGVALVTSDAHAGLLSAIGATLPGASWQRCRTHYATNLMAITPKSSWPWVKTLLHSVFDQPDATSVAAQYDRIIDALADKLPKVADHLEAARSDLLAFTAFPKQIWRQIWSNNPLSVNRPSGDTNLTAA
>NZ_CP009483|2361670:2392391|2365897_2366674_-|WP_023367959.1|DBSCAN-SWA
MAKRLDLKDVNIYYGAFQAVADVSLSILPRSVTAFIGPSGCGKTTVLRTLNRMHEVVPGGRVEGTVLLDDENIYGPGIDPVGVRRAIGMVFQRPNPFPAMSIRDNVVAGLKLQGLRNRKVLDETAEYSLRGANLWDEVKDRLDKPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSALDPISTMAIEDLISELKQDYTIVIVTHNMQQAARVSDQTAFFNLEAVGKPGRLIEIDDTEKIFSNPSQKSTEDYISGRFG
>NZ_CP009483|2361670:2392391|2372815_2373616_+|WP_023367973.1|DBSCAN-SWA
MRMRKVLIGVAAVAVVVLGAVGVDFGASIYAEYRLSTSVRKAANLGSDPFVAILGFPFIPQAMRDRYGELEIKAYAIEHSTVGTATLEATMHSIDLSHASWLIQPDARLSVHELESRIIIDSMHLGRYLGMADLMVQAPLQESNDATGGTTESGISGSHGLVFSGTPKSADFDRRVSVAVDLSIDPHSQETLVITPTGVVTGPDTADQPVPDDKREAVLHAFSSRLPNQKLPFGVAPNTVGARGSDVIIEGITYDVTVALTGFRQS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023367953.1|2361670_2362861_+|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_023367957.1|2365218_2365887_+	phosphate transport system regulatory protein PhoU	NA	NA	NA	NA
WP_023367959.1|2365897_2366674_-	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-17	34.6
WP_023367961.1|2366687_2367602_-	phosphate ABC transporter, permease protein PstA	NA	NA	NA	NA
WP_080674221.1|2367598_2368591_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_023367965.1|2368697_2369822_-	phosphate ABC transporter substrate-binding protein PstS	A0A2R8FEI2	Cedratvirus	5.5e-05	41.5
WP_023367967.1|2369940_2370882_-	mycothiol synthase	NA	NA	NA	NA
WP_023367969.1|2370878_2371643_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	8.9e-15	34.6
WP_023367971.1|2371755_2371989_+	hypothetical protein	NA	NA	NA	NA
WP_023367973.1|2372815_2373616_+	DUF2993 domain-containing protein	NA	NA	NA	NA
WP_036393799.1|2373908_2374376_+	DUF4395 domain-containing protein	NA	NA	NA	NA
WP_023367977.1|2374414_2375257_+	sulfurtransferase	NA	NA	NA	NA
WP_023367979.1|2375258_2375561_+	DUF1416 domain-containing protein	NA	NA	NA	NA
WP_023367983.1|2375693_2376365_+	FABP family protein	NA	NA	NA	NA
WP_042312135.1|2376487_2378890_+	hypothetical protein	NA	NA	NA	NA
WP_023367989.1|2378999_2380511_+	serine/threonine protein kinase	NA	NA	NA	NA
2381028:2381087	attL	NA	NA	NA	NA
WP_023364740.1|2381351_2383295_-|integrase	integrase	A0A1B1P7C7	Bacillus_phage	4.3e-05	24.4
WP_036393475.1|2383291_2384326_-|integrase	integrase	A0A166YH27	Gordonia_phage	4.9e-08	26.3
WP_023364744.1|2384397_2385459_-|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.3e-66	43.8
WP_023367992.1|2385549_2386287_-	hypothetical protein	NA	NA	NA	NA
WP_023367994.1|2386532_2386769_+	hypothetical protein	NA	NA	NA	NA
WP_023364744.1|2388283_2389345_+|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.3e-66	43.8
WP_036393475.1|2389416_2390451_+|integrase	integrase	A0A166YH27	Gordonia_phage	4.9e-08	26.3
WP_023364740.1|2390447_2392391_+|integrase	integrase	A0A1B1P7C7	Bacillus_phage	4.3e-05	24.4
2392656:2392979	attR	NA	NA	NA	NA