CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012559	Lactobacillus heilongjiangensis strain DSM 28069 chromosome, complete genome	2 crisprs	WYL,DinG,RT,cas3,DEDDh,cas14j,csa3,PrimPol,cas9,cas1,cas2,csn2	0	10	2	0

1. NZ_CP012559

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012559_1

• CRISPR_ID: NZ_CP012559_1
• CRISPR_location: 2238390-2238491
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP012559_1

Consensus_repeat	Method
AAACATATAAGACATATTAGTAACATT	CRISPRCasFinder

spacers of NZ_CP012559_1

>1.1|2238417|48|NZ_CP012559|CRISPRCasFinder
ACTAGTATCAAAAGAACTTAGATCAAGCGCCTGAACTGACGCATTATT

CRISPR arrays and Neighbor proteins around NZ_CP012559_1

CRISPR arrays

The CRISPR arrays of NZ_CP012559_1

>merge|NZ_CP012559|1|2238390-2238491|CRISPRCasFinder
AAACATATAAGACATATTAGTAACATTACTAGTATCAAAAGAACTTAGATCAAGCGCCTGAACTGACGCATTATTAAACATATAAGACATATCAGTAACATT

>NZ_CP012559|1|1|2238390-2238491|CRISPRCasFinder
AAACATATAAGACATATTAGTAACATT	ACTAGTATCAAAAGAACTTAGATCAAGCGCCTGAACTGACGCATTATT
AAACATATAAGACATATCAGTAACATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012559.1|WP_041501207.1|2245508_2246324_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224054
NZ_CP012559.1|WP_041501203.1|2248607_2249720_-|glycerate-kinase	unknown	unknown	gnl|CDD|376844
NZ_CP012559.1|WP_041501213.1|2235548_2236913_-|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl|CDD|308794
NZ_CP012559.1|WP_041501204.1|2248036_2248528_-|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_CP012559.1|WP_041501214.1|2233221_2233686_-|universal-stress-protein	unknown	unknown	gnl|CDD|238182
NZ_CP012559.1|WP_041501215.1|2228126_2230073_-|peptidase-M13	unknown	unknown	gnl|CDD|341056
NZ_CP012559.1|WP_041501219.1|2221199_2221646_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133384
NZ_CP012559.1|WP_041501202.1|2249785_2250589_+|tyrosine-protein-phosphatase	unknown	unknown	gnl|CDD|379135
NZ_CP012559.1|WP_041501210.1|2241904_2243074_-|metallophosphoesterase	unknown	unknown	gnl|CDD|277347
NZ_CP012559.1|WP_041501206.1|2246326_2246815_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012559.1|WP_048699129.1|2233703_2234924_-|carboxylate--amine-ligase	unknown	unknown	gnl|CDD|226433
NZ_CP012559.1|WP_041501205.1|2247051_2247600_-|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl|CDD|377025
NZ_CP012559.1|WP_041501208.1|2244832_2245507_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012559.1|WP_041501217.1|2224945_2225647_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NZ_CP012559.1|WP_082330690.1|2221690_2222395_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235914
NZ_CP012559.1|WP_041501259.1|2220238_2220562_-|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|223672
NZ_CP012559.1|WP_041501211.1|2239979_2241890_-|asparagine-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl|CDD|223444
NZ_CP012559.1|WP_041501209.1|2243476_2244001_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP012559.1|WP_041501216.1|2226313_2227564_-|MFS-transporter	unknown	unknown	gnl|CDD|162098
NZ_CP012559.1|WP_082330691.1|2230676_2232620_-|peptidase-M13	unknown	unknown	gnl|CDD|341056

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012559.1|WP_041501207.1|2245508_2246324_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.90284e-31
NZ_CP012559.1|WP_041501203.1|2248607_2249720_-|glycerate-kinase	gnl|CDD|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	2.25969e-50
NZ_CP012559.1|WP_041501213.1|2235548_2236913_-|BspA-family-leucine-rich-repeat-surface-protein	gnl|CDD|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.01213e-27
NZ_CP012559.1|WP_041501204.1|2248036_2248528_-|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.39776e-31
NZ_CP012559.1|WP_041501214.1|2233221_2233686_-|universal-stress-protein	gnl|CDD|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	6.21666e-17
NZ_CP012559.1|WP_041501215.1|2228126_2230073_-|peptidase-M13	gnl|CDD|341056	cd08662, M13, Peptidase family M13 includes neprilysin and endothelin-converting enzyme I. The M13 family of metallopeptidases includes neprilysin (neutral endopeptidase, NEP, enkephalinase, CD10, CALLA, EC 3.4.24.11), endothelin-converting enzyme I (ECE-1, EC 3.4.24.71), erythrocyte surface antigen KELL (ECE-3), phosphate-regulating gene on the X chromosome (PHEX), soluble secreted endopeptidase (SEP), and damage-induced neuronal endopeptidase (DINE)/X-converting enzyme (XCE). Proteins in this family fulfill a broad range of physiological roles due to the greater variation in the active site's S2' subsite allowing substrate specificity. NEP is expressed in a variety of tissues including kidney and brain, and is involved in many physiological and pathological processes, including blood pressure and inflammatory response. It degrades a wide array of substrates such as substance P, enkephalins, cholecystokinin, neurotensin and somatostatin. It is an important enzyme in the regulation of amyloid-beta (Abeta) protein that forms amyloid plaques that are associated with Alzeimers disease (AD). ECE-1 catalyzes the final rate-limiting step in the biosynthesis of endothelins via post-translational conversion of the biologically inactive big endothelins. Like NEP, it also hydrolyzes bradykinin, substance P, neurotensin, and Abeta. Endothelin-1 overproduction has been implicated in various diseases including stroke, asthma, hypertension, and cardiac and renal failure. Kell is a homolog of NEP and constitutes a major antigen on human erythrocytes; it preferentially cleaves big endothelin-3 to produce bioactive endothelin-3, but is also known to cleave substance P and neurokinin A. PHEX forms a complex interaction with fibroblast growth factor 23 (FGF23) and matrix extracellular phosphoglycoprotein, causing bone mineralization. A loss-of-function mutation in PHEX disrupts this interaction leading to hypophosphatemic rickets; X-linked hypophosphatemic (XLH) rickets is the most common form of metabolic rickets. ECEL1 is a brain metalloprotease which plays a critical role in the nervous regulation of the respiratory system, while DINE is abundantly expressed in the hypothalamus and its expression responds to nerve injury. A majority of these M13 proteases are prime therapeutic targets for selective inhibition.	0
NZ_CP012559.1|WP_041501219.1|2221199_2221646_-|MerR-family-transcriptional-regulator	gnl|CDD|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.77557e-43
NZ_CP012559.1|WP_041501202.1|2249785_2250589_+|tyrosine-protein-phosphatase	gnl|CDD|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	1.0773e-89
NZ_CP012559.1|WP_041501210.1|2241904_2243074_-|metallophosphoesterase	gnl|CDD|277347	cd07402, MPP_GpdQ, Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain. GpdQ (glycerophosphodiesterase Q, also known as Rv0805 in Mycobacterium tuberculosis) is a binuclear metallophosphoesterase from Enterobacter aerogenes that catalyzes the hydrolysis of mono-, di-, and triester substrates, including some organophosphate pesticides and products of the degradation of nerve agents. The GpdQ homolog, Rv0805, has 2',3'-cyclic nucleotide phosphodiesterase activity. GpdQ and Rv0805 belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	5.2007e-05
NZ_CP012559.1|WP_048699129.1|2233703_2234924_-|carboxylate--amine-ligase	gnl|CDD|226433	COG3919, COG3919, Predicted ATP-grasp enzyme [General function prediction only].	7.48212e-98
NZ_CP012559.1|WP_041501205.1|2247051_2247600_-|DNA-3-methyladenine-glycosylase-I	gnl|CDD|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	2.2109e-114
NZ_CP012559.1|WP_041501217.1|2224945_2225647_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.56089e-104
NZ_CP012559.1|WP_082330690.1|2221690_2222395_-|SDR-family-oxidoreductase	gnl|CDD|235914	PRK07041, PRK07041, SDR family oxidoreductase.	1.12351e-42
NZ_CP012559.1|WP_041501259.1|2220238_2220562_-|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	6.24e-28
NZ_CP012559.1|WP_041501211.1|2239979_2241890_-|asparagine-synthase-(glutamine-hydrolyzing)	gnl|CDD|223444	COG0367, AsnB, Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism].	4.36175e-148
NZ_CP012559.1|WP_041501209.1|2243476_2244001_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.00846e-06
NZ_CP012559.1|WP_041501216.1|2226313_2227564_-|MFS-transporter	gnl|CDD|162098	TIGR00900, multidrug_transporter, H+ Antiporter protein. [Transport and binding proteins, Cations and iron carrying compounds].	5.1342e-86
NZ_CP012559.1|WP_082330691.1|2230676_2232620_-|peptidase-M13	gnl|CDD|341056	cd08662, M13, Peptidase family M13 includes neprilysin and endothelin-converting enzyme I. The M13 family of metallopeptidases includes neprilysin (neutral endopeptidase, NEP, enkephalinase, CD10, CALLA, EC 3.4.24.11), endothelin-converting enzyme I (ECE-1, EC 3.4.24.71), erythrocyte surface antigen KELL (ECE-3), phosphate-regulating gene on the X chromosome (PHEX), soluble secreted endopeptidase (SEP), and damage-induced neuronal endopeptidase (DINE)/X-converting enzyme (XCE). Proteins in this family fulfill a broad range of physiological roles due to the greater variation in the active site's S2' subsite allowing substrate specificity. NEP is expressed in a variety of tissues including kidney and brain, and is involved in many physiological and pathological processes, including blood pressure and inflammatory response. It degrades a wide array of substrates such as substance P, enkephalins, cholecystokinin, neurotensin and somatostatin. It is an important enzyme in the regulation of amyloid-beta (Abeta) protein that forms amyloid plaques that are associated with Alzeimers disease (AD). ECE-1 catalyzes the final rate-limiting step in the biosynthesis of endothelins via post-translational conversion of the biologically inactive big endothelins. Like NEP, it also hydrolyzes bradykinin, substance P, neurotensin, and Abeta. Endothelin-1 overproduction has been implicated in various diseases including stroke, asthma, hypertension, and cardiac and renal failure. Kell is a homolog of NEP and constitutes a major antigen on human erythrocytes; it preferentially cleaves big endothelin-3 to produce bioactive endothelin-3, but is also known to cleave substance P and neurokinin A. PHEX forms a complex interaction with fibroblast growth factor 23 (FGF23) and matrix extracellular phosphoglycoprotein, causing bone mineralization. A loss-of-function mutation in PHEX disrupts this interaction leading to hypophosphatemic rickets; X-linked hypophosphatemic (XLH) rickets is the most common form of metabolic rickets. ECEL1 is a brain metalloprotease which plays a critical role in the nervous regulation of the respiratory system, while DINE is abundantly expressed in the hypothalamus and its expression responds to nerve injury. A majority of these M13 proteases are prime therapeutic targets for selective inhibition.	0

Protein sequences

>NZ_CP012559.1|WP_041501213.1|2235548_2236913_-|BspA-family-leucine-rich-repeat-surface-protein
MDTSNVTNMSQMFLNCRSLKELNLSSFNTNSVQDMSQMFSGCSDLRMLNITNFDTKKVTNMNGMFAGCETLEELDLSNFDTKNVKSMDNMFQSSDALKSLKLGEKFVVPKNKEHNLKLVNRTWVDVGTGTIKNPKPTNKEGISSVELLKHHDKGNWVVKPEKAYQGDFKLIIANNLNKDIVMDVPEDIRPEYIGSSFEMMVPQIIGYNADKKILHVTATDKGLISDDKVNYTKIESEVDPRTVTFDKPVEAVKPAEPVTPKVQPTSSVQLAEKVAPKPEKKVEVQPAEKTETKVETKPEEKEKPAEKAEPTKPTVAGKVSKFMHYVTVHPDIQSAQTYNTNGQINKGDQLRQNYSWFSDKQLQIGSQKYYHVVGDSWIKAEDVYRYQEFQNIVKTKDVVMTHLVNSRAEELTNRGLGALSTWQTSKEALIGDHKYYQITTNEFVDADSVDLMNA
>NZ_CP012559.1|WP_048699129.1|2233703_2234924_-|carboxylate--amine-ligase
MNVYGMARAFHELYGGTVKAYADIQLAPTRYTKILNLTLHPGFSEDPVFIEKMREIAKVYQNHEEPVILIGCGDGYAELISKHKEELSKTFVCPYVDYDLLKSLNNKESFYNVADKHGLPHPLTKIITKDMYESKQDMDVPFDFPVALKPANSVEWLDIHFEGRKKAFTIHSQEEYMSIVGKIYGNGYKSDLILQDFIPGDDSNMRVLNAYVDQDHHVKMMCLGHPILEDPTPQSIGNYVAIVPEFNQDVYDRVQKFLEDIEFTGYANFDMKYDSRDDTFKFFEINLRQGRSSFFVTLNGYNLAKYVVEDYVEGSLENEPTVYANKNKAQHKLWLGVPVKVFNKYAAKNDATKYADELIKQDRVGTTVFYDKDRSFRRWMLLTYMFHNYVKRFDEYFEENKGRDFK
>NZ_CP012559.1|WP_041501214.1|2233221_2233686_-|universal-stress-protein
MDEIKGYKVKKVDYSKILICVDSDDFVSSKNAFNYACSLARHHNAELGIVSVLETGDLNIFQSLDPEVLKERREEIKELLAMYGEKAEDYGVKNIHLMVTEGTPGTTIVDKVIPSFKPDLVIVGVEEKNRTRNTIGSQAAKIVNNSRCSVSVIR
>NZ_CP012559.1|WP_082330691.1|2230676_2232620_-|peptidase-M13
MLMSKVVGGAGDMVNAKPADFKDNLYLAVNGAWQEKAEIPSDKSRTGGFMDLDEGVEKKLMKEFHEFADGEKELDDELMEQAVKLYRLTNNVDHLSKFHQQPILKDMQRISDLNNLQDLSENMAQLSKDGFPLPIDGEVDADMKDTAKNALYIGGASLILPDKSYYDKDNESGKKLLAKYAEIAGRLLSMIGYKLDDAKEIVDKALAFDKALLPIVKSSEEWADYTKVYNPMDFTEFITKSDKLDLKSLVTDLINDTPEKVIITEPRYLDNLNKLVNDDTFEDIKAWMMVKFLTGNASILDEEFRQTIGEYQLAKSGAKELQNRTKYAYHFASGMFSEVVGAYYGKKYFGEKAKANVREMVKKMISIYEQRLSNNDWLSEDTKKKAIVKLDKIVIKVGYPDKIQDIYSKFQINENDSLYDNVSRIKKIITQDSLDQFHKPVDREKWLMPGHMVNACYDPSRNDITFPAAILQAPFYSLDQTSSQNFGGIGAVIAHEISHAFDNNGAQFDEYGNMNNWWTKEDYAKFQELTKKVIDEFDGIPYAGSKVNGTLVVSENVADVGGLRCALEAAKEDADFDVKAFFTNWAKVWRNKSTKQLTEMFLSVDVHSPAPLRANVMAQNMDEFYDAFDVKPGDGMWLDPDKRVNIW
>NZ_CP012559.1|WP_041501215.1|2228126_2230073_-|peptidase-M13
MRINKIIGGAGDLALDTKPTDYKDNLYLAVNGKWQEKAEIPADKSSAGASVDLELEIEKNLMQEFHDFAKDDSSINDSELLQAIKLYRVANNEETSQMVQNNSILKDIDRIKALSSVNDLSKNFASLSKDNFILPLEMFVEADMKNTAKNVVFVNGADLFLPDKSYYDEDNEFGHKLLAKYVDVATKLLEKLGYSDADAKDTVKKASAFDNLLVPVVKTAEEWAEYTEIYNPYEFNDFGAKSDTLDLKTWVTDEIKATPEKVIVVQPRYMDNLNKLVNDDNFENIKAWMIVRYLMDNAEFVSEDFRQIYGEFKLARSGAKELPTRTKYAYHLAERTFSEVVGVYYGKKYFGEKAKADVREMIKKMINIYEQRINDNDWLGEDTKKKAIVKLEKIVLKVGYPDKVEAIYKKLKVDENATLYDNMVQLNKVLVQDNLDDYHKPVDRTKWAMPGHMVNACYDPTRNDITFPAAILQAPFYSLKQTSSENYGGIGATIAHEISHAFDNNGAQFDEYGNMHNWWTKEDYAHFKGLTQEMIDQFQGIVYAGGKVNGKLVVSENIADVGGMRCGIEAAKSEPDYDPKQFFIQWAKSWRFKATQEYNEDLLATDVHAPQPMRANVMSQDLDEFFEAFDVKEGDGMWLATDKRINIW
>NZ_CP012559.1|WP_041501216.1|2226313_2227564_-|MFS-transporter
MEQETFAIKNWRRNIYLFLTGQFLSGITSMIVQYAIIWYLTKQTGSATVLSMATLLGMLPMILLSPFVGPYVDRTNKKALLIIPDIIAALVAIVLAMVGFLTHEFPIWLVFISLVIRAIVQTFQMPTIQSILPTMVPQDQLTKINGQLGMVQSANYIIAPALGAFLFAIISMPVLILFDVLGAIIGVTIILFVKIPEYPKTDEKVRVLADAKFGLDLLRSKKGLWYMTLMGTVFTLLFMPAVSMYPLMTMSYFKGTVAQAGIIEMIYSVGALIGGTIIGFLGNWSDRIRPLIWSMFIMGITMGMSGFLPQNYTGFLWFFALNAISGIATPFFNTLLMAMIQQSYPPEQLGRVLGIMNSLMSLAGPVGLIFAGPLADKIGVNNLFVIAGLGTIVCGIFVFMNATTRNYDKELQKEID
>NZ_CP012559.1|WP_041501217.1|2224945_2225647_-|ABC-transporter-ATP-binding-protein
MAYIEVRNESKRYHMGETTIIANNNLNFNVDKGKLTVILGPSGAGKSTILNILGGMDTPTEGQVIIDGTDIAQFSERELTTYRRNDVGFIFQFYNLIPNLTTKENVELASAIVKDALDATRILQAVGLGDRVDNFPSQLSGGEQQRVAIARALAKNPKLLLCDEPTGALDYETGKQVLTLLQNASHIDNKTVIVITHNSALAKMADRVIRIHDAKVQSIEDNPYPTPVQDIEW
>NZ_CP012559.1|WP_082330690.1|2221690_2222395_-|SDR-family-oxidoreductase
MSLENDKVLIIGGTSGFGKEVAIMAKHKKADVYVIGRDQERVNQLRYEENIQGSSLDAQNKEQLNHFFDKYGSFDHIVSMLGGAMGGGFLDSPMAEIREAIEDKFFANLQLVQIASKHLRNKGSIILTSGSGGHPYDASGAIIGNQAINTMVEGTAVELAPDHRINAVSPTWTPTGLWRDMNSKQLAQQKDNVAENVPLGRVARIDEVASAYIYLMENDFITGQVLRVDGGVDL
>NZ_CP012559.1|WP_041501219.1|2221199_2221646_-|MerR-family-transcriptional-regulator
MPVEIEKRYRIGDFSELVGLNSPTLRYYEKEGLIKPHRTDNGVRYYTDMDARWVRFLLHLKSTGMTIEQLKLYVKLRAEGDSTINQRIELLEEVRKNFEVEFQQLQDSWTILNDKLDWYKGKMGGHIEDSEQFSEYLESLNHGYLQDR
>NZ_CP012559.1|WP_041501259.1|2220238_2220562_-|carboxymuconolactone-decarboxylase-family-protein
MAKQTAGHDLLGDFAPQFAELNDDVLFGEVWSKESELSAHDRSLITIASIISAGNLEQLDAHLKIGKKNGITKEEIVAEITHLSFYAGWPKAWSAFNRAKEIWKDEK
>NZ_CP012559.1|WP_041501211.1|2239979_2241890_-|asparagine-synthase-(glutamine-hydrolyzing)
MCGIVGFVDKNIADKKPVIEAMMDTIKHRGPNSSGELLEGDTALGFRRLSIIDINSGMQPIYNEDRSKAVIFNGEIYNYQDVRKELKKAGHIFTTDTDTEVLLHGFEEWGIEGLLKKIRGMFAFVIYDLKTGDITGARDFFGIKPLYYYNREGTFIFGSEIKSFLKEPNFKKELNKAALKPYLTFQYSAMNETFFKNVFKIPEGHYFTFKNGKLSIKKYWDMEFKENNLSFEETVKRIDKSLRDSVEEHSISDVPVGSLLSSGVDSSYVTAILKPQHTYSIDFDTSTYEEGTAAKELADKLGLENTRGIVTKEEAIKSLPLIQYYMDEPDANPSSVPLYFLTKLASRDVTVILSGEGADELFAGYANYGFHSHSKAIRVVAEDLKKLPKGVKYKLARGLKKMPNFPGRLHLYESTAKAEEFFIGQAKIFTEKEAADLVKPEFEKSRSVHDIVMRSYNKVRDYNDEVKKMQYLDLHQFMANDIILKADRMSMANSMELRVPFLDKEVAKVAAGVPTKYLLNSKDSKYALRVAAERALPKEWAKREKLGFPVPIRDWIRTKEVYEDFRKLFSADFAGEFFDQDAILKMLDGCYRGENDDRRKVWTIYTFLIWYKVYFIDGGKKPDVDPKVFVPEDEEK
>NZ_CP012559.1|WP_041501210.1|2241904_2243074_-|metallophosphoesterase
MKIKNIARSVLTPRPSEFISTQTDNFLRRLKPRPFVVDYIEGVYKNNVLPNVNDDTVTISVLTDTHAKAVVSSSYYGINGMRHIIEANYVSDHLGVDLNVHLGDLMDGSDKPEISRGILKFAVENYQASKAPFFIIEGNHDENDKYDEHRFFKTASFHRDDYDSLVTKYDYEQSEIQRLNPVSRVGWFDKGSIRIVFIDTSDIPYILSNGSKKYDFKKVRGVREQQLEDLTTVLERTVDKHVVVMGHANIISPSGRSALNFNGDLVQQLLVAFNNKASGQLKNELTGDFGVNIRYDFSSTGISKVTTYICGHMHYEKNYKVSEINHIILNCSALMGKKHGLTTDYNKKWDRRYNEISELAGYFINIDPNKLRLQIYGYGAATRYVSFEI
>NZ_CP012559.1|WP_041501209.1|2243476_2244001_-|GNAT-family-N-acetyltransferase
MSNIYLRQSTLDDLPRIIKIIDSAKKTLRNRGVNQWQNGYPNDEILEQDIQEDISYVLILNGRVVGVAALQQGYDQNYQDMTSGSWASNSDVTYSVIHRIAIEADHQGEHLSSALIQQLLTMSYHLGYCDVRIDTHPDNLVMQHIIESSGFEEKGTITMDEDLGVRKAYQILLK
>NZ_CP012559.1|WP_041501208.1|2244832_2245507_-|hypothetical-protein
MKVRIFLKSYLQLIFQDFWYLTMLFAIIVFGLTADHLLGIDSIKKYSLLLIGSFFLSLFATMNLYHNDSRQNKYLKQKVASYWADTLSQFLVALIVNIFSGSLIFIFSLILNRNILLDTVGILTLIAVGFLGSSIATLFKTQWGRHSSLGQVGVLVFVYLALSGSVISLLDYVEWLLPPLSKIIVTLQSKPFIPQLLPITGQTFLYGLVLFIISSLIYRPKKMH
>NZ_CP012559.1|WP_041501207.1|2245508_2246324_-|ATP-binding-cassette-domain-containing-protein
MKLISVNDLSLQNNGYFAFKHVAFSLSQNEIIGINGDNGSGKTQLLEAIANYQTPDSGTIEYTPGVRIGYLPQDNPQVVDQTVAKYLENIRRISKDLAVRKEQLQGMITFLGVSPYLNQPVRQLSLGLRRRIDFLAAVAGHPNVLLLDEPFAFQSKKTIKNMLSLMQDLKKNGSGIILSATSFDKEVSQYLDTGYLLAENKLTKIESTTNKELKCRLIFSVHPNSVAVTSDIERYITSNLNNVVKLDIPLALKNAMVEKMTRLNYHLEEVL
>NZ_CP012559.1|WP_041501206.1|2246326_2246815_-|hypothetical-protein
MNSETISKLAEKLYEDRNKIEEKSQTFEAQAVYDILDSLEVLRKPIKEYFDMTEDDYYQNESDHRLTLQSPTHKLSELHDRVQVNHVDGSLDAHEINFTYNHEDPYAGGDYKVKTDLNLVSFAFTVIGAVYDNTIVADVRNSLSKDAVLSIGLAAHAIEAWQ
>NZ_CP012559.1|WP_041501205.1|2247051_2247600_-|DNA-3-methyladenine-glycosylase-I
MRCEWANSSEEMQSYHDNEWGTPNHDERYFFEMLTLEAAQAGLSWATIIKRRETYRKAYDNFDIDKVAAFDQAKRDVLLQDKGIIRNRLKVDSSINNAKLIQEMHQHGENFFEYIWNFVDNKPIINHYSDMSEVPAQTELSQRISKDLKKRGFRFVGPTIIYSYLQAVGVINDHVDACDFKY
>NZ_CP012559.1|WP_041501204.1|2248036_2248528_-|universal-stress-protein
MEQDYKRILVPVDGSNEAEMAFKKAVTVAKMNGGHIDVLTVLDTKQFIGLHGGMLNGDVIYQLSEDAQKYLNELKEGAVKDGFKEDDIDIHVRFGEPKTVISQEFIEEYKNDLIMIGSTGMNAVTRLLVGSVSEYVTRNARTDVIIVRTDIDNKKLVDKKHKK
>NZ_CP012559.1|WP_041501203.1|2248607_2249720_-|glycerate-kinase
MKFIIAPGKYSNHVSSEKIGQAIYSGILRALPNAEIATMPVTDSKDGMPALVEHTIGGHWSELPFFDAFWTSKTGRYLVTNIDSQDTAIIDSEQVVGVDLAKNKSRDQLFHATSYGIGELIVDAVTSGIRNIVLCLGKTAVADGGLGVLQALGAKIYDESGSLIPEGENPLINVNRIDLEDVYELLGKRTRINVLLNFSSSYRLSDTVEYLNEAQESFLEDNLVYITEKMNQKYNLDIHPMPHSDSIKTLAGALAMINARISRSSFEWVAKVTGMNDTIRSADILITATDKISGDSMHDDILYHLSRVAGSEKIPTFVLCNNFVDNFNNYEQLFTGIFSTQMTEYDDEITIFENYESVANQLARTLLAFK
>NZ_CP012559.1|WP_041501202.1|2249785_2250589_+|tyrosine-protein-phosphatase
MANDNERVLNLEKGVNFRELGGYQTTDGRTVKYHKILRSAGLADLTDADLQYLKDYGLKIDVDFRSKQEIDKKPDKRPAGVRYVWAPVFEEDETKSSEVQSDSYIPEIDGDPTDGYAHMVDVYRDIITKDSSKAAYRKFFNQLLLNKNDNEVLIFHCSAGKDRTGMGAVFLLTALGVPFETIKEDYLLTNVANKEFVTDLLGLLDSKGYKDPDVINSVKDLMTVHYNYLATAIKTINKTYGNIDKYIKNELKVSPSEIESLKKIYLE

Crispr_ID: NZ_CP012559_2

• CRISPR_ID: NZ_CP012559_2
• CRISPR_location: 2539093-2540580
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 22 spacers
• Cas_protein_info: csn2,cas2,cas1,cas9

Consensus repeat of NZ_CP012559_2

Consensus_repeat	Method
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	PILER-CR
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CRISPRCasFinder
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CRT

spacers of NZ_CP012559_2

>2.1|2539129|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
TAAAACACATGACAACATGCTGCACGATCA
>2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
CATGAAATCTTGAATCAATAGCTATAGTTT
>2.3|2539261|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
GATCCTAACAACAATGGAAAAGATCTCTAT
>2.4|2539327|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
CACCAGTATCGTAAGCCAACTGATACAGGC
>2.5|2539393|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
GAGAGAGGATCTCAGTCAAAGCAGCGAAAT
>2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
TATTTTATGGTGATAAGAAATTACGAATGT
>2.7|2539525|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
TTGATGAAGAAGCGCGTGTTAGTACTGATA
>2.8|2539591|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
ATATTGACAAGTAATCGTTAATGTCTACTT
>2.9|2539657|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
CCCGTATTTAGTTCACGTGGTCATAGTAAA
>2.10|2539723|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
AGATGAACTTTTGTCCAAGCGAAAACCTCA
>2.11|2539789|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
AATTGTTCTGTATGAATACTTATTTTTGAG
>2.12|2539855|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
CATGTATTTGACTTCGTTAACGATAGCGTT
>2.13|2539921|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
TGAATACACGTCCATCAGGTCGTTCATCAT
>2.14|2539987|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
TGTTATACGTGTCACAGGCGCAAGACTGAG
>2.15|2540053|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
TTTACTATGCCTGATGACAAAGCTGATGTT
>2.16|2540119|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
AAATCTTACACAGCCTTTGTTAAATGCCAT
>2.17|2540185|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
GTTCAATCTATTAATAACTCTTCAACTTCT
>2.18|2540251|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
TGATATTGATACAGCTAAACGTTCAATGAG
>2.19|2540317|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
GTTGCCTTTAGTCCGAAATGCTGATTTAAA
>2.20|2540383|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
GAATACTATCATCCGGTTCACTGACCTCTT
>2.21|2540449|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT
GAACAGGCAGCCATTGAGTTAATCGCTGCT
>2.22|2540515|30|NZ_CP012559|CRISPRCasFinder,CRT
AAAATGTATTGACCCCCCACTTCTAACAGG

CRISPR arrays and Neighbor proteins around NZ_CP012559_2

CRISPR arrays

The CRISPR arrays of NZ_CP012559_2

>merge|NZ_CP012559|2|2539093-2540580|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCTAAAACACATGACAACATGCTGCACGATCAGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCCATGAAATCTTGAATCAATAGCTATAGTTTGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCGATCCTAACAACAATGGAAAAGATCTCTATGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCCACCAGTATCGTAAGCCAACTGATACAGGCGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCGAGAGAGGATCTCAGTCAAAGCAGCGAAATGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCTATTTTATGGTGATAAGAAATTACGAATGTGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCTTGATGAAGAAGCGCGTGTTAGTACTGATAGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCATATTGACAAGTAATCGTTAATGTCTACTTGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCCCCGTATTTAGTTCACGTGGTCATAGTAAAGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCAGATGAACTTTTGTCCAAGCGAAAACCTCAGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCAATTGTTCTGTATGAATACTTATTTTTGAGGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCCATGTATTTGACTTCGTTAACGATAGCGTTGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCTGAATACACGTCCATCAGGTCGTTCATCATGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCTGTTATACGTGTCACAGGCGCAAGACTGAGGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCTTTACTATGCCTGATGACAAAGCTGATGTTGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCAAATCTTACACAGCCTTTGTTAAATGCCATGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCGTTCAATCTATTAATAACTCTTCAACTTCTGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCTGATATTGATACAGCTAAACGTTCAATGAGGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCGTTGCCTTTAGTCCGAAATGCTGATTTAAAGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCGAATACTATCATCCGGTTCACTGACCTCTTGTTTTAGAAGTATGTCATCTCAATTACTTAAGAACCGAACAGGCAGCCATTGAGTTAATCGCTGCTGTTTTAGAAGTATGTCATCTCATTTACTTATGAAACAAAATGTATTGACCCCCCACTTCTAACAGGGTTTTAGAAGTATGTCATCTCAATTATTTATGATCC

>NZ_CP012559|2|1|2539093-2540514|PILER-CR
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TAAAACACATGACAACATGCTGCACGATCA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CATGAAATCTTGAATCAATAGCTATAGTTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GATCCTAACAACAATGGAAAAGATCTCTAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CACCAGTATCGTAAGCCAACTGATACAGGC
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAGAGAGGATCTCAGTCAAAGCAGCGAAAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TATTTTATGGTGATAAGAAATTACGAATGT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TTGATGAAGAAGCGCGTGTTAGTACTGATA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	ATATTGACAAGTAATCGTTAATGTCTACTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CCCGTATTTAGTTCACGTGGTCATAGTAAA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AGATGAACTTTTGTCCAAGCGAAAACCTCA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AATTGTTCTGTATGAATACTTATTTTTGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CATGTATTTGACTTCGTTAACGATAGCGTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGAATACACGTCCATCAGGTCGTTCATCAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGTTATACGTGTCACAGGCGCAAGACTGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TTTACTATGCCTGATGACAAAGCTGATGTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AAATCTTACACAGCCTTTGTTAAATGCCAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GTTCAATCTATTAATAACTCTTCAACTTCT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGATATTGATACAGCTAAACGTTCAATGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GTTGCCTTTAGTCCGAAATGCTGATTTAAA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAATACTATCATCCGGTTCACTGACCTCTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAACAGGCAGCCATTGAGTTAATCGCTGCT
GTTTTAGAAGTATGTCATCTCATTTACTTATGAAAC

>NZ_CP012559|2|2|2539093-2540580|CRISPRCasFinder
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TAAAACACATGACAACATGCTGCACGATCA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CATGAAATCTTGAATCAATAGCTATAGTTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GATCCTAACAACAATGGAAAAGATCTCTAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CACCAGTATCGTAAGCCAACTGATACAGGC
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAGAGAGGATCTCAGTCAAAGCAGCGAAAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TATTTTATGGTGATAAGAAATTACGAATGT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TTGATGAAGAAGCGCGTGTTAGTACTGATA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	ATATTGACAAGTAATCGTTAATGTCTACTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CCCGTATTTAGTTCACGTGGTCATAGTAAA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AGATGAACTTTTGTCCAAGCGAAAACCTCA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AATTGTTCTGTATGAATACTTATTTTTGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CATGTATTTGACTTCGTTAACGATAGCGTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGAATACACGTCCATCAGGTCGTTCATCAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGTTATACGTGTCACAGGCGCAAGACTGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TTTACTATGCCTGATGACAAAGCTGATGTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AAATCTTACACAGCCTTTGTTAAATGCCAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GTTCAATCTATTAATAACTCTTCAACTTCT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGATATTGATACAGCTAAACGTTCAATGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GTTGCCTTTAGTCCGAAATGCTGATTTAAA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAATACTATCATCCGGTTCACTGACCTCTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAACAGGCAGCCATTGAGTTAATCGCTGCT
GTTTTAGAAGTATGTCATCTCATTTACTTATGAAAC	AAAATGTATTGACCCCCCACTTCTAACAGG
GTTTTAGAAGTATGTCATCTCAATTATTTATGATCC

>NZ_CP012559|2|1|2539093-2540580|CRT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TAAAACACATGACAACATGCTGCACGATCA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CATGAAATCTTGAATCAATAGCTATAGTTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GATCCTAACAACAATGGAAAAGATCTCTAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CACCAGTATCGTAAGCCAACTGATACAGGC
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAGAGAGGATCTCAGTCAAAGCAGCGAAAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TATTTTATGGTGATAAGAAATTACGAATGT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TTGATGAAGAAGCGCGTGTTAGTACTGATA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	ATATTGACAAGTAATCGTTAATGTCTACTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CCCGTATTTAGTTCACGTGGTCATAGTAAA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AGATGAACTTTTGTCCAAGCGAAAACCTCA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AATTGTTCTGTATGAATACTTATTTTTGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	CATGTATTTGACTTCGTTAACGATAGCGTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGAATACACGTCCATCAGGTCGTTCATCAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGTTATACGTGTCACAGGCGCAAGACTGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TTTACTATGCCTGATGACAAAGCTGATGTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	AAATCTTACACAGCCTTTGTTAAATGCCAT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GTTCAATCTATTAATAACTCTTCAACTTCT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	TGATATTGATACAGCTAAACGTTCAATGAG
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GTTGCCTTTAGTCCGAAATGCTGATTTAAA
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAATACTATCATCCGGTTCACTGACCTCTT
GTTTTAGAAGTATGTCATCTCAATTACTTAAGAACC	GAACAGGCAGCCATTGAGTTAATCGCTGCT
GTTTTAGAAGTATGTCATCTCATTTACTTATGAAAC	AAAATGTATTGACCCCCCACTTCTAACAGG
GTTTTAGAAGTATGTCATCTCAATTATTTATGATCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012559.1|WP_041499991.1|2532962_2537033_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|374653
NZ_CP012559.1|WP_041499995.1|2529905_2530220_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP012559.1|WP_041499983.1|2541085_2541706_-|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|225462
NZ_CP012559.1|WP_053085060.1|2532108_2532792_-|hypothetical-protein	unknown	unknown	gnl|CDD|226809
NZ_CP012559.1|WP_041499977.1|2546395_2548087_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|163244
NZ_CP012559.1|WP_041499998.1|2527540_2528485_+|hexose-kinase	unknown	unknown	gnl|CDD|237405
NZ_CP012559.1|WP_041499982.1|2541818_2542469_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP012559.1|WP_041499981.1|2542605_2543265_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP012559.1|WP_041499992.1|2531272_2532109_-|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl|CDD|372824
NZ_CP012559.1|WP_041499974.1|2549232_2549685_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012559.1|WP_041499978.1|2545532_2546297_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012559.1|WP_041499994.1|2530834_2531236_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133384
NZ_CP012559.1|WP_041499979.1|2543758_2545453_+|hypothetical-protein	unknown	unknown	gnl|CDD|238899
NZ_CP012559.1|WP_041499989.1|2537185_2538061_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|187851
NZ_CP012559.1|WP_041499972.1|2549693_2550845_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|182528
NZ_CP012559.1|WP_041499975.1|2548422_2548911_-|prolyl-tRNA-synthetase-associated-domain-containing-protein	unknown	unknown	gnl|CDD|239827
NZ_CP012559.1|WP_041499987.1|2538065_2538371_+|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|226043
NZ_CP012559.1|WP_041499996.1|2528512_2529508_+|tagatose-bisphosphate-aldolase	unknown	unknown	gnl|CDD|183502
NZ_CP012559.1|WP_041499986.1|2538367_2539072_+|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl|CDD|213411
NZ_CP012559.1|WP_041499984.1|2540640_2541081_-|flavodoxin-domain-containing-protein	unknown	unknown	gnl|CDD|235854

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP012559.1|WP_041499991.1|2532962_2537033_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	0	1054.8	70.6
NZ_CP012559.1|WP_041499987.1|2538065_2538371_+|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	2.5e-40	131.6	0.8
NZ_CP012559.1|WP_041499989.1|2537185_2538061_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	5.6e-87	286.1	8.8
NZ_CP012559.1|WP_041499986.1|2538367_2539072_+|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	3.6e-56	184.9	11.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012559.1|WP_041499991.1|2532962_2537033_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl|CDD|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	6.08774e-139
NZ_CP012559.1|WP_041499983.1|2541085_2541706_-|NAD(P)H-binding-protein	gnl|CDD|225462	COG2910, COG2910, Putative NADH-flavin reductase [General function prediction only].	1.15809e-63
NZ_CP012559.1|WP_053085060.1|2532108_2532792_-|hypothetical-protein	gnl|CDD|226809	COG4372, COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain [Function unknown].	0.000776798
NZ_CP012559.1|WP_041499998.1|2527540_2528485_+|hexose-kinase	gnl|CDD|237405	PRK13508, PRK13508, tagatose-6-phosphate kinase; Provisional.	1.07207e-133
NZ_CP012559.1|WP_041499982.1|2541818_2542469_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	8.67124e-40
NZ_CP012559.1|WP_041499981.1|2542605_2543265_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	2.14822e-36
NZ_CP012559.1|WP_041499992.1|2531272_2532109_-|DNA/RNA-non-specific-endonuclease	gnl|CDD|372824	pfam13930, Endonuclea_NS_2, DNA/RNA non-specific endonuclease.	4.17453e-54
NZ_CP012559.1|WP_041499977.1|2546395_2548087_-|FAD-dependent-oxidoreductase	gnl|CDD|163244	TIGR03385, Coenzyme_A_disulfide_reductase, CoA-disulfide reductase. Members of this protein family are CoA-disulfide reductase (EC 1.8.1.14), as characterized in Staphylococcus aureus, Pyrococcus horikoshii, and Borrelia burgdorferi, and inferred in several other species on the basis of high levels of CoA and an absence of glutathione as a protective thiol. [Cellular processes, Detoxification].	1.95466e-124
NZ_CP012559.1|WP_041499994.1|2530834_2531236_+|MerR-family-transcriptional-regulator	gnl|CDD|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.13723e-28
NZ_CP012559.1|WP_041499979.1|2543758_2545453_+|hypothetical-protein	gnl|CDD|238899	cd01918, HprK_C, HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent phosphorylation of Ser-46 of HPr and its dephosphorylation by phosphorolysis. The latter reaction uses inorganic phosphate as substrate and produces pyrophosphate. Phosphoenolpyruvate carboxykinase (PEPCK) and the C-terminal catalytic domain of HprK/P are structurally similar with conserved active site residues suggesting these two phosphotransferases have related functions. The HprK/P N-terminal domain is structurally similar to the N-terminal domains of the MurE and MurF amino acid ligases.	0.00186574
NZ_CP012559.1|WP_041499989.1|2537185_2538061_+|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	8.30766e-92
NZ_CP012559.1|WP_041499972.1|2549693_2550845_-|ABC-transporter-permease	gnl|CDD|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	1.34424e-39
NZ_CP012559.1|WP_041499975.1|2548422_2548911_-|prolyl-tRNA-synthetase-associated-domain-containing-protein	gnl|CDD|239827	cd04335, PrdX_deacylase, This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the YbaK and ProX proteins, and the prolyl-tRNA synthetase-editing domain (ProRS-INS), specifically hydrolyzes Ala-tRNA(Pro). In this CD, many of the eukaryotic editing domains are N-terminal and cis-acting, expressed from a multidomain ProRS, however, similar to the bacterial PrdX, the mammalian, amphibian, and echinoderm PrdX-like proteins are trans-acting, single-domain proteins.	4.71121e-61
NZ_CP012559.1|WP_041499987.1|2538065_2538371_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.904e-23
NZ_CP012559.1|WP_041499996.1|2528512_2529508_+|tagatose-bisphosphate-aldolase	gnl|CDD|183502	PRK12399, PRK12399, tagatose 1,6-diphosphate aldolase; Reviewed.	0
NZ_CP012559.1|WP_041499986.1|2538367_2539072_+|type-II-A-CRISPR-associated-protein-Csn2	gnl|CDD|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.33453e-51
NZ_CP012559.1|WP_041499984.1|2540640_2541081_-|flavodoxin-domain-containing-protein	gnl|CDD|235854	PRK06703, PRK06703, flavodoxin; Provisional.	2.71138e-29

Protein sequences

>NZ_CP012559.1|WP_041499986.1|2538367_2539072_+|type-II-A-CRISPR-associated-protein-Csn2
MTNSITIFPYQPFEIGSGLTLFNFQNKSEFSQLIFRLHNLKKHTTLTDDTNRILHFYTDPKNPFDENIKDVELLGDLNSFDINSATQLKIILKKVVANSTIIKDEIEGANSELNNLVFEAITQYTVPLSMDFYANFEKILKAKGVFVDTSKWQNYCDKIMDVISFYSEFSSKKLLVFYGLERLLSLDQLNEIDEYLKSVDLTIISLESYPMLLKEKGLNIKVYSIDNDHVRFDY
>NZ_CP012559.1|WP_041499987.1|2538065_2538371_+|CRISPR-associated-endonuclease-Cas2
MRLMIMFDLPTLTAMDRRNYRQFRKKLLQDGFTMMQESIYTCILIDRQAANLLNNKISLYAPKKGLVQSLIVTEKQFASMNFLTGEKDNSEENTFERLTVI
>NZ_CP012559.1|WP_041499989.1|2537185_2538061_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTIYITQKAKLSYKANHLLIQTDMDLKQIPFHQINCIVIATTQSVITGYLVSELIENNIKVVFCSPDHNPCAELNGYYNNIQRNQNIEDQISWSIPAKQELWTDIVKNKIENQIALMEKDNLDTSDIVTEYSSIQANDSTNREAVIARKYFPALFNEDFTRGSDSKVNAMLNYGYTILLSATNQEVAAQGYLTQLGIHHHSLRNCFNLSSDLMEPFRQFVDSKVLERIDYDFDEYVKLELVDVLNHEITYNDKTFILKNALSQYIHDCFSFLNSQRDTIGKVGFKNEV
>NZ_CP012559.1|WP_041499991.1|2532962_2537033_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MSKKDSEYYIGLDIGTNSVGWAVTNGKYDLLNIKKKNLWGVRLFEAAESAAGRRINRSTRRRYRRRRNRINWLNEIFADELSKVDPSFLTRLNSSWISKKDSSRTRDKYNLFMDADYTDKNYHHKYPTIYHLRRDLMFDDKQFDIRLVYLALHNIIKYRGNFTYDHRKFNVSEMSSNLTKALENFNQELMEFEDAFPDNTDYSAISEVLLKSNNVSTKIDEIISNLELDKDTKKYLKEVLKLILGNSANLNTIFHTSLDKDDEKLSLSAKDIELKLNNLDSLLSDEQIHFISSANELYSSITLNDILDGKTYLSLAKIKQYDTHCSDLQELKEMWYKTTNPDLIKKSRKAYKEYVHGSYNTEDFYKAISPFLKIAIPEDLAKDALKKIDANTYLPKQRTSNNGVIPFQLNLIELEKIIDNQSKYYPFLKENREKIISILSFRIPYYVGPIQAPTDKNFSWMVKKIQAKARPWNFDEVIDREKSSNNFIKRMTTTDTYLVGEPVLPKNSLIYQKFEVLNELNNIRISKNLSQDPLGSKLSVEVKQQIFEELFKRYKTVKSDQLKKWLIRNSYFTDPTIIGLSKPSEFNSSLSTFIDMKAIFGMDFVNNPRNSSQLEELAEWLTVFEDKQILSEKIRHSNYPYSDQQIRKISNMRYRGWGRISKKLLCDIKVESTIYKSHQLHPYSILDLMWSTNNNFYSILHKDKYNFESILEDYNLGTDDKTDINELVDNIHTSPALKRGIIQSINIVKELVKFMGHAPQHIFLEFTREDKTSTLSESRKKRLKKLYNNLSEDTKKFKLDLRDYLVPDKSIQKELESHDKDLSKERLMLYFLQNGKSLYSDEALDINRLSEYQVDHILPRTYIKDDSLENKALVLAKENQRKADDLLLQPSIINKNMERWIYMKDHGMISPKKFKNLTRTTITEDDKVHFINRQLVQTSQIIKNVANILDNMYKEQGTTCVETKANLSSAFRTAFSEQDDKYHFKHPEFIKNRDVNDFHHAQDAYLACLLGLYRIQRFPSDEMLLIKKEYRKFFAQAQNSVKNHGKIPDSQKNGFILAPLVNGETLINNKTMETIWNMDYKRKVIKIFNYKQYNITKRTEIKTGEFYKQTLYSPHDENVKNPIPQKKNLDPKIYGGYSGVQSSYLAIIKVDQKKPTMVSVPIRFSKMIDDGKLSLQSWLENNIKHKKTIEVLKTKIPIGQLTYNPKNGYLSVQSEKEIANAQQLFLPFEHVALLTLLHAPTSEYDQILSFYDTDILLEIFDEITNKIKTFFPFYIDEQEYLVSIRENFQSATVIEKVNVLQQLLIMLHANSSRISIKLGEVSKKDLGRKKKRIPLENTDLVYQSVTGLYQTKFHID
>NZ_CP012559.1|WP_053085060.1|2532108_2532792_-|hypothetical-protein
MTRIVGVVAFGFIIYFIVKMFKTRKLDKTIQTKAIRKHYRNGLLLSILIMIITLGFGGGGTSEQTDSKQTGSAETTKVVKKQKYIGKDKYQIAKKENVALLAKKKKLQEQADSLQSQKDKIASDEAAAKQKEQEQQAAAQKQQAEQAKQQQEQAAAAQKQQQSQQSASQTQTKGDMNTSDSGSIVGNVNSHIYHVPGQAGYNMNSSNAVYFHNEQEAINAGYRRAKR
>NZ_CP012559.1|WP_041499992.1|2531272_2532109_-|DNA/RNA-non-specific-endonuclease
MKKLVRFLVLLALVPATATVTTQSQAASKSNVKTEYVKNYSYQKKTKKLVSKNKQLKKSISKLQQEIADNQKFLDDHNNKPTQTAANTDLANMNYNGTQEIVVNNNNPSFNQDDLSTAKGAWQQYGDLDNLNRVTAANALLNISLMPSAKREPLHWNPTGWHNKKINGGWLYNRSHLIGYQLTGQNNNPKNLMTGTRSLNSPEMLAHEMDIAYYLKQSSSHYIRYRVTPVFRGDELLPRGVQMEAQSIGDNAVHFNVYIFNVQSGVTLNYADGTSQIG
>NZ_CP012559.1|WP_041499994.1|2530834_2531236_+|MerR-family-transcriptional-regulator
MKISEVSKTVGLSIPTIRYYCDLGLVPSIQRDLDGERVFDDESITWLKGIKFQRDLGLSLSEIQTYLQLSQKTGPAALKKRHALLLEQRKKAQSDLDAATERLNCLDEKIRLEEAIIKGTKKDSLSAARRFSQ
>NZ_CP012559.1|WP_041499995.1|2529905_2530220_+|hypothetical-protein
MVPANFELARNAITSMVAVLLIVIYIIYMISKYSHRDKEKVWTGDTILLTFIAIYCVYITLMNFVKLPASLDYINTIVTFVFMAVVIIFIISSIFKKTTNKSKK
>NZ_CP012559.1|WP_041499996.1|2528512_2529508_+|tagatose-bisphosphate-aldolase
MYMTTAKKYAALEKMSDKNGVIAALAIDQRGSLKKMLAAAANKPANEEDIVEFKKAIASELTPYASAILLDPEYGLPASKVRAAGSGLLVSYEKTGYDATEPGRLPDLISVWSVRRLKEAGADSIKFLLYIDPDEDKSIIDQKEAFVERIGDECVAEDIPFFVELVTYDDSIGDVKSAEYAKVKPHKVIEAMKEFSKPKYNIDVLKVEVPINLDYVEGFNGDNPVVYTKDEAIKYFKEQSDATNLPYIFLSAGVTAKAFRDELHLAKDADAKFNGVLCGRATWRGAIEPFAKDGEEAGKKWMNDQGKKNIEELNEVLAETATSWKEKVSKD
>NZ_CP012559.1|WP_041499998.1|2527540_2528485_+|hexose-kinase
MSNSVLTITMNPSVDISYPLEHLNIDTVNRVKDVSKTAGGKGLNVTRVLKQLSVDVTASGIIGGTIGQYITNQLDENDIDHAFMKISQESRNCIAILHDNGDQTEILEAGPILSKDDENAFLEHFDDQVSSFNLVTISGSLPQGLSKALYSKMVNVAAKHNVPVILDSSNEALRLALESDVKPFMIKPNQDEIAQLIGKEISDLNDLKDKLATEEIFQGIPWVVVSLGSQGAFVKYQNNFFKVNIPKIHAVNPVGSGDSTVAGLAAGIVKDEKPEDIMKRAMTVGILNTLQEKTGNIDISQYEDYFEKVDIVKY
>NZ_CP012559.1|WP_041499984.1|2540640_2541081_-|flavodoxin-domain-containing-protein
MKVLLTYTSMTGRNEKIANYLADYLKEKGADVDLEEIIDTDAFGLTDYDAVIVESYTYHDGEVPDEAQDFYEDLADVDLERTKFAVLGSSSKKHIHFGRAVDYFTMQLNSSNGEQVSDSVKIDQDPDEDDFKRVRDLGDRVLKSLK
>NZ_CP012559.1|WP_041499983.1|2541085_2541706_-|NAD(P)H-binding-protein
MKIAVIGANGKEGSLIVKEALSRNLDVTSIVRDAKKSPTDKYLVRDVYSLKAEDIKDFDVLVDALGFFGPSVKEYVPAMEHLIEIIGNAKTRLLVVGGAGSLYVDKAHTTKLYQQADFPDAIKPLSEEMAKSLDILRDSKIDWTFISPAADFQAKAERTGKYVLAGEELTFNDEGKSEISYADFALAMVDEILADKHSKERISVRW
>NZ_CP012559.1|WP_041499982.1|2541818_2542469_+|histidine-phosphatase-family-protein
MAYQIYLVRHGKTWYNEYEKMQGWSDTPLTDEGVAVAQKAAESLRTVDFAAAVTSDMKRAVDTTRIITRRNINNLVPQELSEFREQFYGYFEGRSIDESWFAIGKPHQARTFTDIVKKYGFDATMDFVKEADPLHDAESAQEYWSRIDRGFKKIDQIAHDGDKILLVTHSITILGLAVRYKTPELEINDIPANASLTLMERDNGVNKLTKYNQSLI
>NZ_CP012559.1|WP_041499981.1|2542605_2543265_+|histidine-phosphatase-family-protein
MAKYQIYLVRHGRTWFNKYNKMQGWSDTPLAPEGVEVAKKAAHALKDVDFAAAFSSDARRAIDTCKLIVDENINHDKITPQKLMEFREEFYGYYEGMNSPEAWFMVGEPHGAKSFAEIIAKYGMDATKDFMKEADPFHDAENAEEYWNRVNKGFEKLDEIAKDGDKILLVSHGTTIRSITDRYNDGNFDVTVSPRNSSLTMMTRDNGENKVTSYNQLLD
>NZ_CP012559.1|WP_041499979.1|2543758_2545453_+|hypothetical-protein
MSNSLQAIESKAFYINPNRSVAVINYNEEYVQDIFQLINSKGFHNLVDLYLEESQLAVTNKVEGLQADTYIGILKAVLIDDKPTYEKYGNEQILKSIEDFYSYYRSYFRVSLINKHSSAIVKGNFMNIDNRFNEVVLHLYRAIEEKIQGFSNRTYRQINAGTNACVLTQSVKWAAPQNYQALESIRFLDTIMLRPPMMMHTKSNKREGVFSAVKDNPIDKFDGDQKDWYCFPAKIGESLAFIYFHRDYFVSGIALANLFEVADADSIAGQKPDEIILFGLKKTEGDVSHYYHDEENDIWVGEVPYNDKTTYFGYMKKMCLTVHNLHMIYESRLPIHGSMVNISFSNGKTKSVVFFGDSGAGKSESIEALQEVADDKIINIETIFDDMGSFAFDEKGNVYAQGTETGAFVRLDDLSSSVAFNNMDRGIYLNPELKNARVILPANTYKHVVEHHSIDMWVYANNYDSEIGLHQFPDEDHAKATFIAGKRKALGTTDEVGMSTTFFANPFGPVQEEEKTRPIIDKVFNKLYQDKVYVGEIYTHLGYDKSKDSLQESAKELLSELMNN
>NZ_CP012559.1|WP_041499978.1|2545532_2546297_-|hypothetical-protein
MKKTLMIIVSLLVFVLPLSAYSVNALNSSNAQEIKREESARLISRNQKIWQKHIAKADVIHSDEFSTRKAFISTSLEQLQNHSQTVIEGTVYNLQKMSSPEEMSYTKATIYVNRVISGDTSLKDKQIYLALDGGLVSFDRWYSHSGRPKDQNREMLIKNDEFPLPKIGSKIIVGLIPNHLDEPTEYNVALKRSGFTINNSYAIENPRYNVWVKAPDSSKYQLNNPKMRRQTNAQQTQDLQKLTQQINQKYNKKY
>NZ_CP012559.1|WP_041499977.1|2546395_2548087_-|FAD-dependent-oxidoreductase
MANKKIVIVGGVGGGASAAARARRLDESAEITMYEKGPNVSFSNCSLPYHLSGLIPDADSIVMKTPEQFHKQYNINAEVNSEVIDVDAQQKTVQVKDVNTGEIRTSAYDELVLSPGANPIMPKSIKGIDKSNVFSVRNVVDIKALQAYLTDNQVSDVAVIGGGFIGLEVVENIAQTGKKLTLVEAADHVLGTIDDDFAQLVHKNLYDNGVQVILNDGLAEISDQHITLTSGKEIKAQAVVMAIGVSPDTTLAKNAGCRIGVTGGIEVNQQFETSIPDIYAVGDAIEVTNMITRQKTRLALAFPAQMEARDAVDHMYGRPVQNQGVIGSQVIHLFDLNVASTGLTEAACKQNGFDHRSVTVIPQNRVGVMPDTSPIFLKLVFSYPGGEVLGAQAIGKSGVDKQIDVIATMISMHGNISNLTHLELAYSPWFSTAKNAVNIAALVAENILNGEYQQVSISKVRGLVESGAFIIDAREPNEYAAGHITTSINIPLSQFRQRLDEIPTDKPVYIHCQSSQRSYNMVRALNNLGYTNVTNISGSFLELKQYEYFKDQTTDRKSILTNY
>NZ_CP012559.1|WP_041499975.1|2548422_2548911_-|prolyl-tRNA-synthetase-associated-domain-containing-protein
MSPFEQVKAELAKLNISYDIVEHPAVFTTDVADEYIKGKVGVRTKSLFLTNKKKKAFYLVFMDDDKRLDMNHFAEIVGEKHIKFASEASLMEKLGLKPGVVSIFGLLNNKEKDVQVYFEKDIVGDIPLTFHPNDNTKTIFVKMDDLVKFLNDLGFEYNVIEL
>NZ_CP012559.1|WP_041499974.1|2549232_2549685_-|hypothetical-protein
MKNLYKLDRLSVLGTVLISILIQVIQMILTDPNVSEMPQMGKWLKLLIYVIGAVLAFAIAYWLFNLLLKNNDNYKAKLIINMAIGLTIEACLMIIVFLIAGKTNIWIKGIVGVIGFGSMAGLNWKFLEVSQSDKIKISVLTAIWFILTLF
>NZ_CP012559.1|WP_041499972.1|2549693_2550845_-|ABC-transporter-permease
MTDKIMIALKSIGKNKNRNFLTMLGIIIGIASVICILAIGDGFTHTVTKGMGSHDTRNKVTLQWQSTSDYNTDGGFTPNDASVLSKVPGVDHVKLTSSIVEAGAKVQYKTKNISIGLNKQPKHLKLVKGTYFNMTGASNGVYISEDLAHRLFKENAINRLISIDGTVFVVQGIYHISDMNYRPDAYVSKQIFKDLFANQISKDQAKLYVQPDANKKQVGKTAVKRMKKMGEQKHTGDYSVSNPDAISKQFTRVLNDITYFIAFIAGISLLIAGIGVMNVMYITVSERRKEIGIRRAFGATSSDIRNQFLIESVVLCVIGGIIGIIFGYIFVSIINAFLPFKAVITVYAIILSLSVSTAVGLIFGFIPSNKAAKSELVGLLKEE

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP025475	Lactobacillus curvatus strain IRG2 plasmid pIRG201, complete sequence	20051-20080	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP037436	Lactobacillus plantarum strain EM plasmid pEM7, complete sequence	20164-20193	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP037436	Lactobacillus plantarum strain EM plasmid pEM7, complete sequence	31552-31581	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP042372	Lactobacillus malefermentans strain CBA3618 plasmid unnamed1, complete sequence	17291-17320	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NC_014386	Lactobacillus helveticus R0052 plasmid pIR52-1, complete sequence	5144-5173	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP021482	Lactobacillus brevis strain SRCM101174 plasmid pLB1174-4 sequence	6441-6470	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP021482	Lactobacillus brevis strain SRCM101174 plasmid pLB1174-4 sequence	16681-16710	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP021482	Lactobacillus brevis strain SRCM101174 plasmid pLB1174-4 sequence	26917-26946	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP021502	Lactobacillus plantarum strain SRCM102022 plasmid pPL2022-1, complete sequence	20937-20966	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP021458	Lactobacillus brevis strain ZLB004 plasmid p2, complete sequence	11861-11890	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP021477	Pediococcus pentosaceus strain SRCM100892 plasmid pPC892-6	1666-1695	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP016271	Lactobacillus plantarum subsp. plantarum strain CGMCC 1.557 plasmid pLp1, complete sequence	31255-31284	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP031213	Lactobacillus brevis strain UCCLB521 plasmid pUCCLB521_E, complete sequence	2700-2729	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP014882	Lactobacillus backii strain TMW 1.1991 plasmid pL11991-1, complete sequence	118-147	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP014875	Lactobacillus backii strain TMW 1.1989 plasmid pL11989-2, complete sequence	10863-10892	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP014631	Lactobacillus backii strain TMW 1.1988 plasmid L11988-7, complete sequence	14090-14119	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP014632	Lactobacillus backii strain TMW 1.1988 plasmid L11988-8, complete sequence	17791-17820	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP018764	Pediococcus acidilactici strain BCC1 plasmid pbcp1, complete sequence	5830-5859	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP015340	Lactobacillus brevis strain 100D8 plasmid unnamed2, complete sequence	1132-1161	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP015340	Lactobacillus brevis strain 100D8 plasmid unnamed2, complete sequence	28608-28637	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP019582	Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence	17715-17744	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP019583	Lactobacillus helveticus strain LH5 plasmid pCBTLH5_2, complete sequence	1242-1271	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP042397	Leuconostoc citreum strain CBA3623 plasmid unnamed4, complete sequence	13093-13122	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP016493	Lactobacillus pentosus strain BGM48 plasmid pBGM48-2, complete sequence	6054-6083	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP016493	Lactobacillus pentosus strain BGM48 plasmid pBGM48-2, complete sequence	8567-8596	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP027191	Lactobacillus sp. CBA3605 plasmid pCBA3605-1, complete sequence	18982-19011	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP019983	Pediococcus inopinatus strain DSM 20285 plasmid pLDW-13, complete sequence	7431-7460	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP019983	Pediococcus inopinatus strain DSM 20285 plasmid pLDW-13, complete sequence	37900-37929	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP017959	Lactobacillus plantarum strain C410L1 plasmid unnamed5, complete sequence	25889-25918	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_AP018406	Lactobacillus plantarum strain SN35N plasmid pSN35N-1, complete sequence	15808-15837	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_LN898145	Lactobacillus oligofermentans DSM 15707 = LMG 22743 isolate LACOL plasmid II, complete sequence	10651-10680	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP033892	Lactobacillus plantarum strain LMT1-48 plasmid p_4, complete sequence	5463-5492	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP031200	Lactobacillus brevis strain UCCLBBS449 plasmid pUCCLBBS449_B, complete sequence	3344-3373	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP031201	Lactobacillus brevis strain UCCLBBS449 plasmid pUCCLBBS449_C, complete sequence	2822-2851	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP017698	Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-4, complete sequence	25699-25728	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP017701	Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-7, complete sequence	7728-7757	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP035308	Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence	4153-4182	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP035146	Lactobacillus plantarum strain SRCM103357 plasmid unnamed3	56041-56070	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP028262	Lactobacillus plantarum strain SRCM102737 plasmid unnamed1, complete sequence	1037-1066	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP014901	Lactobacillus backii strain TMW 1.2002 plasmid pL12002-2, complete sequence	767-796	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP028223	Lactobacillus plantarum strain SRCM101105 plasmid unnamed1, complete sequence	18878-18907	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NC_020824	Lactobacillus brevis KB290 plasmid pKB290-7, complete sequence	9064-9093	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP014892	Lactobacillus backii strain TMW 1.1992 plasmid pL11992-2, complete sequence	38802-38831	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP013166	Lactobacillus plantarum strain MF1298 plasmid pMF1298-10, complete sequence	2815-2844	0	1.0
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_LN898145	Lactobacillus oligofermentans DSM 15707 = LMG 22743 isolate LACOL plasmid II, complete sequence	25113-25142	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP022131	Lactobacillus pentosus strain SLC13 plasmid pSLC13, complete sequence	8806-8835	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP015859	Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence	91944-91973	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP012296	Pediococcus damnosus strain TMW 2.1536 plasmid pL21536-2, complete sequence	6816-6845	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP046039	Lactobacillus sakei strain CBA3614 plasmid unnamed2, complete sequence	3923-3952	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP040737	Lactobacillus futsaii strain Y97 plasmid p1, complete sequence	8757-8786	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP040737	Lactobacillus futsaii strain Y97 plasmid p1, complete sequence	21384-21413	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP040737	Lactobacillus futsaii strain Y97 plasmid p1, complete sequence	34011-34040	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP040739	Lactobacillus futsaii strain Y97 plasmid p3, complete sequence	12275-12304	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP040739	Lactobacillus futsaii strain Y97 plasmid p3, complete sequence	25067-25096	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_AP014681	Lactobacillus hokkaidonensis JCM 18461 strain LOOC260 plasmid pLOOC260-1, complete sequence	4274-4303	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP032661	Lactobacillus pentosus strain ZFM94 plasmid unnamed2, complete sequence	876-905	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP032661	Lactobacillus pentosus strain ZFM94 plasmid unnamed2, complete sequence	14729-14758	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP032657	Lactobacillus pentosus strain ZFM222 plasmid unnamed3, complete sequence	2457-2486	1	0.967
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	NZ_CP017262	Lactobacillus paracasei strain FAM18149 plasmid pFAM18149.21, complete sequence	28491-28520	4	0.867
NZ_CP012559_2	2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539459-2539488	30	NZ_CP007740	Bacillus methanolicus MGA3 plasmid pBM69, complete sequence	42041-42070	5	0.833
NZ_CP012559_2	2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539195-2539224	30	MK448661	Streptococcus satellite phage Javan96, complete genome	5974-6003	6	0.8
NZ_CP012559_2	2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539459-2539488	30	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	642989-643018	6	0.8
NZ_CP012559_2	2.18|2540251|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2540251-2540280	30	AB812987	Uncultured Myoviridae nrdA, nblA, g04, g03, nrdB genes for ribonucleoside-diphosphate reductase alpha subunit, phycobilisome degradation protein NblA, hypothetical protein, putative RNA ligase, ribonucleoside-diphosphate reductase beta subunit, partial and complete cds, clone: LS201114	19-48	6	0.8
NZ_CP012559_2	2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539459-2539488	30	MK054208	Sulfolobus spindle-shaped virus strain SSV17, complete genome	12383-12412	7	0.767
NZ_CP012559_2	2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539459-2539488	30	MK054205	Sulfolobus spindle-shaped virus strain SSV13, complete genome	3446-3475	7	0.767
NZ_CP012559_2	2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539459-2539488	30	MK054213	Sulfolobus spindle-shaped virus strain M.03.0.42.SSV, complete genome	3171-3200	7	0.767
NZ_CP012559_2	2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539459-2539488	30	MK054219	Sulfolobus spindle-shaped virus strain M.06.0.8v2.SSV, complete genome	2845-2874	7	0.767
NZ_CP012559_2	2.15|2540053|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2540053-2540082	30	NZ_CP038011	Acinetobacter haemolyticus strain TJR01 plasmid pAHTJR2, complete sequence	3562-3591	7	0.767
NZ_CP012559_2	2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539459-2539488	30	MK448953	Streptococcus phage Javan474, complete genome	23796-23825	8	0.733
NZ_CP012559_2	2.16|2540119|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2540119-2540148	30	MN693374	Marine virus AFVG_25M38, complete genome	1633-1662	8	0.733
NZ_CP012559_2	2.17|2540185|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2540185-2540214	30	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	246542-246571	8	0.733
NZ_CP012559_2	2.3|2539261|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539261-2539290	30	MW084976	Bacillus phage Kirov, complete genome	148131-148160	9	0.7
NZ_CP012559_2	2.7|2539525|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539525-2539554	30	NZ_CP021816	Sinorhizobium meliloti strain M270 plasmid accessoryB, complete sequence	166942-166971	9	0.7
NZ_CP012559_2	2.13|2539921|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539921-2539950	30	NZ_CP013369	Burkholderia ubonensis strain RF23-BP41 plasmid pRF23, complete sequence	89597-89626	9	0.7
NZ_CP012559_2	2.13|2539921|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2539921-2539950	30	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	128399-128428	9	0.7
NZ_CP012559_2	2.21|2540449|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2540449-2540478	30	KU726251	Enterobacteria phage SEGD1, complete genome	164463-164492	9	0.7
NZ_CP012559_2	2.21|2540449|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2540449-2540478	30	MT679221	Proteus phage 7, complete genome	166585-166614	9	0.7
NZ_CP012559_2	2.21|2540449|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT	2540449-2540478	30	NC_027402	Salmonella phage SPN3US, complete genome	165711-165740	9	0.7

1. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025475 (Lactobacillus curvatus strain IRG2 plasmid pIRG201, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

2. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037436 (Lactobacillus plantarum strain EM plasmid pEM7, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

3. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037436 (Lactobacillus plantarum strain EM plasmid pEM7, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

4. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042372 (Lactobacillus malefermentans strain CBA3618 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

5. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NC_014386 (Lactobacillus helveticus R0052 plasmid pIR52-1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

6. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021482 (Lactobacillus brevis strain SRCM101174 plasmid pLB1174-4 sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

7. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021482 (Lactobacillus brevis strain SRCM101174 plasmid pLB1174-4 sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

8. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021482 (Lactobacillus brevis strain SRCM101174 plasmid pLB1174-4 sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

9. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021502 (Lactobacillus plantarum strain SRCM102022 plasmid pPL2022-1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

10. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021458 (Lactobacillus brevis strain ZLB004 plasmid p2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

11. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021477 (Pediococcus pentosaceus strain SRCM100892 plasmid pPC892-6) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

12. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016271 (Lactobacillus plantarum subsp. plantarum strain CGMCC 1.557 plasmid pLp1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

13. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031213 (Lactobacillus brevis strain UCCLB521 plasmid pUCCLB521_E, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

14. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014882 (Lactobacillus backii strain TMW 1.1991 plasmid pL11991-1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

15. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014875 (Lactobacillus backii strain TMW 1.1989 plasmid pL11989-2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

16. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014631 (Lactobacillus backii strain TMW 1.1988 plasmid L11988-7, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

17. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014632 (Lactobacillus backii strain TMW 1.1988 plasmid L11988-8, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

18. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018764 (Pediococcus acidilactici strain BCC1 plasmid pbcp1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

19. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015340 (Lactobacillus brevis strain 100D8 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

20. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015340 (Lactobacillus brevis strain 100D8 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

21. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019582 (Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

22. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019583 (Lactobacillus helveticus strain LH5 plasmid pCBTLH5_2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

23. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042397 (Leuconostoc citreum strain CBA3623 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

24. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016493 (Lactobacillus pentosus strain BGM48 plasmid pBGM48-2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

25. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016493 (Lactobacillus pentosus strain BGM48 plasmid pBGM48-2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

26. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027191 (Lactobacillus sp. CBA3605 plasmid pCBA3605-1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

27. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019983 (Pediococcus inopinatus strain DSM 20285 plasmid pLDW-13, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

28. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019983 (Pediococcus inopinatus strain DSM 20285 plasmid pLDW-13, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

29. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017959 (Lactobacillus plantarum strain C410L1 plasmid unnamed5, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

30. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018406 (Lactobacillus plantarum strain SN35N plasmid pSN35N-1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

31. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN898145 (Lactobacillus oligofermentans DSM 15707 = LMG 22743 isolate LACOL plasmid II, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

32. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033892 (Lactobacillus plantarum strain LMT1-48 plasmid p_4, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

33. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031200 (Lactobacillus brevis strain UCCLBBS449 plasmid pUCCLBBS449_B, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

34. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031201 (Lactobacillus brevis strain UCCLBBS449 plasmid pUCCLBBS449_C, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

35. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017698 (Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-4, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

36. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017701 (Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-7, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

37. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035308 (Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

38. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035146 (Lactobacillus plantarum strain SRCM103357 plasmid unnamed3) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

39. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028262 (Lactobacillus plantarum strain SRCM102737 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

40. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014901 (Lactobacillus backii strain TMW 1.2002 plasmid pL12002-2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

41. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028223 (Lactobacillus plantarum strain SRCM101105 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

42. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NC_020824 (Lactobacillus brevis KB290 plasmid pKB290-7, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

43. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014892 (Lactobacillus backii strain TMW 1.1992 plasmid pL11992-2, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

44. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013166 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-10, complete sequence) position: , mismatch: 0, identity: 1.0

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagttt	Protospacer
******************************

45. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN898145 (Lactobacillus oligofermentans DSM 15707 = LMG 22743 isolate LACOL plasmid II, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcctgaatcaatagctatagttt	Protospacer
*********.********************

46. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022131 (Lactobacillus pentosus strain SLC13 plasmid pSLC13, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctataggtt	Protospacer
*************************** **

47. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015859 (Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaattttgaatcaatagctatagttt	Protospacer
********.*********************

48. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012296 (Pediococcus damnosus strain TMW 2.1536 plasmid pL21536-2, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaataactatagttt	Protospacer
********************.*********

49. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046039 (Lactobacillus sakei strain CBA3614 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaattttgaatcaatagctatagttt	Protospacer
********.*********************

50. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040737 (Lactobacillus futsaii strain Y97 plasmid p1, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctataggtt	Protospacer
*************************** **

51. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040737 (Lactobacillus futsaii strain Y97 plasmid p1, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctataggtt	Protospacer
*************************** **

52. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040737 (Lactobacillus futsaii strain Y97 plasmid p1, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctataggtt	Protospacer
*************************** **

53. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040739 (Lactobacillus futsaii strain Y97 plasmid p3, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagatt	Protospacer
*************************** **

54. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040739 (Lactobacillus futsaii strain Y97 plasmid p3, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctatagatt	Protospacer
*************************** **

55. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014681 (Lactobacillus hokkaidonensis JCM 18461 strain LOOC260 plasmid pLOOC260-1, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctataggtt	Protospacer
*************************** **

56. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032661 (Lactobacillus pentosus strain ZFM94 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagccatagttt	Protospacer
**********************.*******

57. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032661 (Lactobacillus pentosus strain ZFM94 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagccatagttt	Protospacer
**********************.*******

58. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032657 (Lactobacillus pentosus strain ZFM222 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.967

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagccatagttt	Protospacer
**********************.*******

59. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017262 (Lactobacillus paracasei strain FAM18149 plasmid pFAM18149.21, complete sequence) position: , mismatch: 4, identity: 0.867

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
catgaaatcttgaatcaatagctagtggct	Protospacer
************************  * .*

60. spacer 2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007740 (Bacillus methanolicus MGA3 plasmid pBM69, complete sequence) position: , mismatch: 5, identity: 0.833

-tattttatggtgataagaaattacgaatgt	CRISPR spacer
atatttt-tggtgataagaaattacatgagt	Protospacer
 ****** *****************. . **

61. spacer 2.2|2539195|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MK448661 (Streptococcus satellite phage Javan96, complete genome) position: , mismatch: 6, identity: 0.8

catgaaatcttgaatcaatagctatagttt	CRISPR spacer
cttgaaatcttgaatcaatggcttttgagt	Protospacer
* *****************.*** * *  *

62. spacer 2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 6, identity: 0.8

tattttatggtgataagaaattacgaatgt	CRISPR spacer
aattttatgttgatgagaaattacccttgt	Protospacer
 ******** ****.*********   ***

63. spacer 2.18|2540251|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to AB812987 (Uncultured Myoviridae nrdA, nblA, g04, g03, nrdB genes for ribonucleoside-diphosphate reductase alpha subunit, phycobilisome degradation protein NblA, hypothetical protein, putative RNA ligase, ribonucleoside-diphosphate reductase beta subunit, partial and complete cds, clone: LS201114) position: , mismatch: 6, identity: 0.8

tgata-ttgatacagctaaacgttcaatgag	CRISPR spacer
-aatacccgatacagctaaacgctccatgag	Protospacer
 .*** ..**************.** *****

64. spacer 2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MK054208 (Sulfolobus spindle-shaped virus strain SSV17, complete genome) position: , mismatch: 7, identity: 0.767

tattttatggtgataagaaattacgaatgt	CRISPR spacer
cattttatggtgctaagaaattcttaatac	Protospacer
.*********** ********* . ***..

65. spacer 2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MK054205 (Sulfolobus spindle-shaped virus strain SSV13, complete genome) position: , mismatch: 7, identity: 0.767

tattttatggtgataagaaattacgaatgt	CRISPR spacer
cattttatggtgctaagaaattcttaatac	Protospacer
.*********** ********* . ***..

66. spacer 2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MK054213 (Sulfolobus spindle-shaped virus strain M.03.0.42.SSV, complete genome) position: , mismatch: 7, identity: 0.767

tattttatggtgataagaaattacgaatgt	CRISPR spacer
cattttatggtgctaagaaattcttaatac	Protospacer
.*********** ********* . ***..

67. spacer 2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MK054219 (Sulfolobus spindle-shaped virus strain M.06.0.8v2.SSV, complete genome) position: , mismatch: 7, identity: 0.767

tattttatggtgataagaaattacgaatgt	CRISPR spacer
cattttatggtgctaagaaattcttaatac	Protospacer
.*********** ********* . ***..

68. spacer 2.15|2540053|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038011 (Acinetobacter haemolyticus strain TJR01 plasmid pAHTJR2, complete sequence) position: , mismatch: 7, identity: 0.767

tttactatgcctgatgacaaagctgatgtt	CRISPR spacer
tggattatgcctaataacaaagctgatgga	Protospacer
*  *.*******.**.************  

69. spacer 2.6|2539459|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 8, identity: 0.733

tattttatggtgataagaaattacgaatgt	CRISPR spacer
gtttttatgttgataataaattacgctttc	Protospacer
  ******* ****** ********  * .

70. spacer 2.16|2540119|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MN693374 (Marine virus AFVG_25M38, complete genome) position: , mismatch: 8, identity: 0.733

aaatcttacacagcctttgttaaatgccat	CRISPR spacer
tgaaactacacagcctttgataaatgcttt	Protospacer
 .*  .************* *******. *

71. spacer 2.17|2540185|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

gttcaatctattaataactcttcaacttct	CRISPR spacer
ggatgttgcattaatacctcttcaacttct	Protospacer
*  .. * .******* *************

72. spacer 2.3|2539261|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MW084976 (Bacillus phage Kirov, complete genome) position: , mismatch: 9, identity: 0.7

gatcctaacaacaatggaaaagatctctat	CRISPR spacer
tgagataacaacaatggaaaaggtctatga	Protospacer
 .   *****************.*** *. 

73. spacer 2.7|2539525|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021816 (Sinorhizobium meliloti strain M270 plasmid accessoryB, complete sequence) position: , mismatch: 9, identity: 0.7

ttgatgaagaagcgcgtgttagtactgata	CRISPR spacer
ttgatgaacaagcgcgtgctagtctccggc	Protospacer
******** *********.**** .. .  

74. spacer 2.13|2539921|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013369 (Burkholderia ubonensis strain RF23-BP41 plasmid pRF23, complete sequence) position: , mismatch: 9, identity: 0.7

tgaatacacgtccatcaggtcgttcatcat	CRISPR spacer
gtcgtcgacgtcgatcaggtcgttcatcgc	Protospacer
   .*  ***** ***************..

75. spacer 2.13|2539921|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.7

tgaatacacgtccatcaggtcgttcatcat	CRISPR spacer
cgtcaggtcgtccatcaggtcgtccatcag	Protospacer
.*   .  ***************.***** 

76. spacer 2.21|2540449|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to KU726251 (Enterobacteria phage SEGD1, complete genome) position: , mismatch: 9, identity: 0.7

gaacaggcagccattgagttaatcgctgct	CRISPR spacer
ccgaaggtagccattgagttaatctcttaa	Protospacer
  . ***.**************** **   

77. spacer 2.21|2540449|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to MT679221 (Proteus phage 7, complete genome) position: , mismatch: 9, identity: 0.7

gaacaggcagccattgagttaatcgctgct	CRISPR spacer
ccgaaggtagccattgagttaatctcttaa	Protospacer
  . ***.**************** **   

78. spacer 2.21|2540449|30|NZ_CP012559|PILER-CR,CRISPRCasFinder,CRT matches to NC_027402 (Salmonella phage SPN3US, complete genome) position: , mismatch: 9, identity: 0.7

gaacaggcagccattgagttaatcgctgct	CRISPR spacer
ccgaaggtagccattgagttaatctcttaa	Protospacer
  . ***.**************** **   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1471235 : 1481237	10	Prochlorococcus_phage(33.33%)	NA	NA
DBSCAN-SWA_2	2593909 : 2604117	10	Enterococcus_phage(42.86%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP012559|1471235:1481237|DBSCAN-SWA
TCTAGTGTTTAAAGTGTCTTCTACCAGTGAAGACCATTGCAATTCCAAATTTATCAGCCATGTCGATTGAATCTTGATCCTTGATTGAACCACCTGGTTGAACAATTGCAGTGATGCCATGTTCAGCAGCGTATTGCACACAGTCGTCCATTGGGAAGAAAGCATCTGAAGCCATGATAAGTGGTGAATGTGTTTCAGCCTTTTCTTCTTGTTCGATAGCAATTTTAACTGAACCAATACGATTCATTTGACCAGCACCGATACCTAAAGTCTTGTCAGTTGTTGTAATAACGATGGCATTACTCTTAACATGCTTAACAACTTGTTGACCGAATAATAGAGCTTTCATTTCTTCGTCAGTTGGAGCTTTCTTAGTAACAACCTTGAATTCATCCATTTGATCAACTGTTGTATCACGTTCTTGAACTAACAAGCCACCCATAACTGAAACGTATTCGTGTTTGTCAGCTGCTTTTGCTTGTGAAAAGTCGAGTGTCAATAGACGGATATTCTTCTTAGCTTCCAAAATTTCCAAAGCTTCATCAGTAAAACTAGGAGCAATAACAATTTCAAGGAAGATCTTGTGCATTTCTTCAGCAATTTCTTTAGTTACTTCACGGTTAACCGCAACGATACCACCGAAAATTGACATTGTATCGGCTGTATAGGCTTTGTGCCAAGCTTTGTAGATACATTCATCATCAACACCGACACCACATGGATTCATGTGCTTCAAGGCAGCAACACAAGGTTGGTCGAAGTCAGCAACGATTCTCAAGGCAGCATCTGCGTCTTTGATATTGTTGAATGAAAGTTCCTTACCATGCAATTGTTTAGCTGAGGCGATTGAATAAGCTGAAGGCATTGCACTTTGATAGAAGGCAGCCTTTTGATGTGAATTTTCACCATAACGTAATTCTTGATGATAGTCGTAACCAAGTACTTCAACGTCAGGGAATTCATCGCCATTAAGATCTGTCAAATAGTGAGCAATGATACTGTCATATTCAGCTGTGTGACGGAAAGCTTTAGCAGCCAAACGACGTCTGAGAACTGTGTCATCTTCATCAGATTTGATGCTTTCCAAAACTGTTTCATAATCACTAGCATCGATAACAACGTAAACGCTCTTGAAATTCTTTGAAGCGGAACGAATCATTGATGGACCACCGATATCAATTTGTTCGATTGCTTCGGCAGGTGTTACGCCATCTTTAGAAATAGTTTCTTTAAATGGATATAAGTTAACACAGACAAGGTCGATAGTTTGAATATTGAGTTTTTCCAAAGTTTGCATGTGTTCAGGATTATCACGTTTTGCTAATAGTCCAGCGTGAACCATTGGGTGCAATGTCTTAACACGGCCATCAAGAATTTCAGGGAACTTAGTAACTTCGTCAATTTCAGTAACTTTAACGCCGTTTTCTTGTAGCTTCTTGTATGTACCACCAGTTGAGATAATTTCAAAATCGTTAGCAATTAAACCTTTAGCAAATTCAACAACACCTGTTTTATCTGAAACACTGATCAAAGCTCTTTTCATTTTTTATCTACCCCATTAGTTTTATTTAGTAAATCAAGAATTACTTGGCGATACATTTGATGCTCAGTTTGGTGAATCCTAGCTTCCAAACTCTCTTCAGTATCATTGGTCAAACGAACAACTTTTTCTTGCTTGATGATTGGACCAGTATCGACCCCTTCGTCAATATAGTGAATCGTTACACCTGTCACCGCATCCCCAGCTTCAAAAGCTCGTTCAATCGCTTCGAGACCAGAAAACTTAGGCAAAAGCGATGGATGAATATTGATAATATGATTTGGATAAGCTGCCAACAAGACAGGCGTAACAACACGCATATAACCTGCTAATAAAATGTATTCAATTTGAAGCGGCTTTAACTTTTCAATAATAGCTTGTTCATACGCACCACGATTAGGATAATCACTCAACTGATTAATAAAAACGGGAATATCATATTTTGCTGCCCGTTCAATCACGTGAGCTTCCTTTTGATCACAAACGACCAATTCGATTTCCAAACCGACGTTGTGCAATTCATCTGACTTGGCAATAGCTTCAAAGTTACTACCGTTTCCCGAGGCAAAGATTGCTACTTTCATAGCTGATCCCCTTTCAAAATCAAACTTTCTTTCGACTTAGGAACGACTTCCCCAATCGTATATGCAACAGTTTCTTTCTCATTCAATAACTCTAAAACTTCCAATTCTTTAGAAGCGTCAACGGTAATTACCATTCCGATACCCATGTTGAAAATATGATACATATCGGCTGTTTCTAATTGACCATACTTTTGTAACAAACCAAATATTGGTAACTTAGGCCAAATATCAACATTGATTTTTGCAGCTAGATTGTCTGGCAACATCCGTGGAATATTCTCATAGAAACCGCCACCGGTGATGTGTGAAATGCCCTTGATCAAACGTTCATCAAGTAATGGCACAATATCTTGCACATAAATCTTAGTTGGTGTCAGTAGTAGCGCACCTAGTGTTTGCTCGGTATATTCTGGCAAAACACTATCGACAGTCAATTTATGTTCTTGGAAGAAAATCTTACGAACTAGTGAATAGCCATTAGAATGAATTCCACTCGACTTCAAGCCAATTAAAACATTGCCGGCTTGAATATTTTCTTTCTTCAATAAATCATCTTTTTCACAGATACCCACTGAGAAACCAGCAATATCATAATCTTTAGCTTCATAAACTCCGGGCATTTCCGCAGTCTCGCCACCAATTAAATTGACATTAGCTTGATTACAACCGGCGATAACTCCCTTGAGGATTTCTTCAATTTTGTCATCAACCTTACCAGTTGAAATATAATCCAAGAAATATTGTGGTGTTGCACCCTGAGCCAAAATATCGTTGACACACATGGCTACACAGTCGATTCCGATGGTATCCCACTTCTTAGCTTCCGTTGTTAACAGCAATTTAGTTCCCACACCGTCATCACTCGAAACTAAAACGGGGTGCTTATAACCTTCGGGAATCTCATAAACACCACCGAAATTTCCGATATTACTGTTATGTGTATTCTGTTTCACAAATTTAGAAATTTTATAACCTGATTCGACGTTAACGCCCGCATCTTGATAGGGATTAGACATTGAATGCCTCCTTATTTTCTAGATTCATAATCGTAAAGATAAGTTGGATAGTCACCATTGAAATATGACATATCTAAACCGGAATATGGTGCATCGGACTTCAAACCGATTGCATCGATCAAGCCTTCTTCACTCAAGAATTTCAACGAATCGGATCCGAATATTTCATTCATTTCTGGAATTGACTTGTGAGCTGCAATCAATTCGCTTTTTTCTTGAATATCGATTCCGTAGAAACAAGGATGCATAAATCTTGGTGACGCGATACGCAAGTGAACTTCCGTTGCTCCAGCATCCCTCAATAGTTGCACGATGTATGCACAAGTTGTCCCACGCACGATTGAATCGTCAACTAAGATAACTCGTTTGCCTTGAACAACACCTTTAACAGCAGCCAACTTTTGACGAACACTCTTTTCACGTAGTTCTTGAGTTGGTTGAATAAATTCACGGCCCATATATTGGTTCTTAATCAAGCCCATTTCATATGGCAAGCCACTTGCTTCAGCGTAGCCACTAGCTGCAGATAATGAGGAGTTCGGTACACCAACGACAATATCGCCAAGTGCTGGAAATTCTTTAGCCAAGTTAGCTCCCATACGTTTTCTAGCCGAGTGAACGTTAACGCCCAAAATATCTGAATCCGGACGAGCAAAGTAGATGAATTCCATTGAACAAATAGCCAATTTCGTATCAGTTGTCCATTGATCAATTTTCATTCCATCATTGTCGATCGTAATCAATTCACCAGGTTGTACGTTGCGAACCAATTTGGCTCCGACAGCGTCCAGTGCACAAGTCTCACTAGCCACAACATATGCTCCATTATCTAATTGACCGATTGAAAGTGGACGGAAACCATGTGAATCCAATGCCACAAGCATGGCATCTTTCGTCAAAAGTAAATATGCAAAACCACCTTGAATCTTATTCAATGCTTCAACAATTTTTTCATGGAAAGTTGGTGCGTTGGAAACTTTAATCAAGTGAACTAATACTTCAGAATCAGAACTAGATTTGAAGATGTGACCTTTTTCTTCTAATTCCTTTTTCAAAGTCACAGCGTTAGTTAGATTACCGTTGTGAGCTAAAGCAATTTGACTGTCCGTAAAATCGAACAAGAGTGGTTGCACATTCTCAATCTTATTTTCACCAGCTGTCGAGTAACGAACGTGTCCAATTGCTGAATCACCAACTAAAGAATTCAAATATTCTGGTTTAGAAAAGACTTGTGTCAACAATCCTAAATTACGATAAGCACGAAGTTTTTTGCCATCATTAGCAACAATTCCGGCACCTTCTTGACCACGATGTTGCAGACTGTGGAGTCCTAAATACGTTAGATAATTAGCATTTTCAGCGCCCCAAACACCAAAGACACCACATTCTTCATTTAAACTTCTTACTTCATTAGGCACGCAATGGCCTCCTTCCAGTTTTTACCGGCTGTTAATCCGTTGATTTCCACAGATTCATCAGCAGTAGTAACTTTGAATTCTGGTGCTGCAGTAACTGTTCCTAAACATTCAATATCAGTAGCTACGAGTTCTTCAAACACAGTTTGATTTTCTGGAGCAACTGTTACTAAGAAACGAGATTGTGTTTCTGAGAACATTTGAGCTGAAGTTAAACTTGTATTGATTTCAAAACCTAATTCATTTTCGAAAGCTGATTTTGACAAGGCAACTGCCAATCCACCTTCTGATAAATCGTGACAACTCATAATTAGCTTTTGAGAAATTGCTTGGCGGATAATATCTTGATGTAATTTTTCTTGGTCTAAATCTAAATTACGCAAGTTTCCTTTTAATTTTCCAGATTGAGCCATTTGTAATTCTGACCCGTTGAAATCGTCTTGAGTTTGACCAACTACATAGATCAAATCACCGGCTTCTTTGAATGCAGTAGTTGTGACATTATCGATATCGGAAATCAAACCGACCATCCCAACCATGGGACTTGGATAAATTGCAACATCGTTGTATTCGTTGTAAAGCGAAACATTACCAGAAATTACTGGTGTATTGATTTTTTCACAGGCACTAGCAATCCCTTCAACACTCTTGTCTAATTCCCAGAAAGCTTCAGGATTTTCAGGATTACCATAATTCAAGCAGTCAGTAACACCAATTGGTTCACCACCACTGGCAACAATATTTCTAGCTGCTTCCATGACGGCAATTTGACCACCAACATATGGATTCAAGTAAACGTATTTCGAGTTGCTATCGTTAGTCATGGCGATAGCTTTTCTTGTACCACGGATTCTAACAACACCACTGTCGCTACCAGGACGAACTAATGTATTAGCTCTAACTTGTGAATCATAAGTTTGGTAGAAATGTTTCTTACTAGCAATATTGGGACGTTGCAACATTTCATTCCAAGTTTTTTCTAGCGAATCAATTACAGGCACAAATTGATAATCTTTGTCATCAATCATGCGTTGTGGTTGAGTTTCTTCACGGTCATATTCAGGAACATCTTCAGTCAAACTGTCGACGGGAATATCGGTTACTAATTCATCATGGTGATAAATCTTATATTGCTTATCAGTTGTAACTTGACCAATCACGACTGCATCAAGTTCAAAGTGCTTGAAGAAAGCCAACACATCATCAACGAATTCTGGTTTAACACAGAGAACCATTCGTTCTTGAGATTCAGATAACATCATTTCGTAGGCGTTCATTTCAGTTTCACGTTGGGGAACTTTATCCAAGTTCAACACGAGACCAGAGCCAGCTTTTGAAGCCATTTCGGCAGTTGATGAAACTAAACCAGCGGCACCCATATCTTGAATACCTAAGATCCATTCAGGATGCTTTTCAATAATTTCAACACAAGCATCCATCAATAGCTTTTCAATAAACGGATTACCAACTTGAACGGCTGAACGTTGTTTGTTCTTAGTATCCGTAAATTCGTCAGAAGCAAATGTTGCACCGTGGATACCATCACGACCAGTTTTAGCACCGACATAGACGATTAAATTCTTATCGCCACTAGCTGTACCGTGCTTGAAATCAGTATTATTCAATAAGCCGACACACATCGCATTTACGAGTGGATTGTGTTCGTAGCAATCTTCAAAGGCAATCTCGCCACCAACTGTTGGCAAACCAATACAGTTACCGTAACCACCGATACCAGCAACAACTTCATTAACTAGGTGCTTTGTTTGACCATCTTTTAAAGGACCAAATTTCAAACTATTCAAAAGTGCAATCGGTTGCGCACCCATTGAAAAAATATCTCTAATGATTCCGCCGACACCTGTTGCTGCACCTTGATAGGGTTCAACCGCAGAAGGATGATTGTGACTTTCAGCTTTAAAGACAACTGCCTGATTATCACCAATATCCAAAATTCCGGCATCTTCACCAGGACCCGCAATCACGCGTTCACTCTTGTTAGGCATCTTGCGAAGAACTTTTTTAGAATTCTTATAAGAACAATGTTCACTCCACATTACTGAATAAAGACCCGTTTCAGTGTAGTTTGGCAAACGTTTGAGAATCTTTGTGCTGATCAAATCATATTCGGAATCTGTTAAACCCCATTGTTGATAAATTTTTTCATCTTTAATTTGTTTTGCCGTAGGTTCAGTCATTAATTATTCACCTTTACTTGATAATTGATTATTGATTGAAATAGTTTCAGTCCATCGTCAGAACCGAGAATTTCTTCAATTGCACGTTCTGGGTGGGGCATCATGCCTAGGACATTCTTTTGTTTGTTAGTTACGCCAGCGATATGTTCCACACTGCCGTTAACATTTTCAAGATATTGGAAAGCAATTTGATCATTGGCTTTTAATTCAGCTAAAGTCTTGTCATCACAATAATAACGACCCTCACCATGAGCGATTGGAATATTGATTACTTCATCTTTTTCATAGCCATTTGTAAAGGCAGTCTGATTATTGACAACTTTTAGAGCAACTGTTTCACAGATAAAGCGACCTTGCTCATTTTTAATCAAGGCACCTGGCAATAAACCAAGCTCTGTTAAAATTTGGAATCCATTACAAATCCCGAGGACAATTTTGCCTTCGTTAGCGAAACGAATAATTTCTTTTACAATTGGGGCATGAACGGCAATCGCACCACTACGCAAGTAGTCACCGTAAGAAAAGCCACCAGGAATCAACACACCATCAAAACCAGCTAAACTTTCAGCTCGATAGTCGACAAGTTCAACTTGTTGTTCAATACCATCACGAATGGCGTAATACAAGTCCATATCGCAGTTAGAACCAGGAAAATTGATTACGGCAAACTTCATCTATTCTGCCTCCGCAATTTCATAACGATAAGTTTCAATATTGGGGTTGGCTAAAAGGTCATCACAGATAGAGTCAACATCTTTTTCCAAGTCAGCATAATCATCGGCAAACTTTAATTCGAAATATTTACCCATGCCCACATTTTCAACTTTGTTGTAACCCATAGAATGGACAGCTGATTTAATAGCTTCTCCTTGAGCGTCTAATACGGAATCCTTTAGAGTGACATACACTTTAACTAATTTCATAATTCTCTCCTATTTGTCTTGTAGTCGTTGCAAAACTGTTTGATAAGTTTCTACTAAATTGCCTTCATGCTTGCGGAAAACATCTTTATCCATTGAATGATGATCATTCTTGTTCCAAATTCGACAATTATCTGGTGAAAATTCATCGACAAGGATAATTTCACCGTTGTATTTACCAAATTCCAACTTGAAATCAACTAAGTCGAAATCAGCTTTAGCAAAGAATGGAATCAACAATTGATTGATTTTCAAAGTCTCTTGTTTGATATATTCAATGTCTTCGTTGTCAGCAATGCCTAGCGCGTGAATTTGAGATTGATTAATCACAGGATCATCCAAAGCATCGCTCTTGTAATAAAATTCAATGATCGGTTCTTTTAACTTTTGGCCTTCTTCAATTTGGAACTTACGTACCAAAGACCCGGAAGTAATATTTCTTAAAACAACTTCCAATGGAAATACTTGAGTTTTCTTAACTAATTGTTCATGGTCAGAAAGATTCTTAACCAAGTGTGTTTTGATACCATTTTCGATTAAATAATTAAAAACAATTTGTGAAATCTGACAATCCAGAACACCCTTACCTGGTAAAATTTCTTTCTTCTTACCATTCAATGCTGTGGCTTGGTCTTTATAAACAATCAAAACTTCGTCGTCATTTTCTGCTTGGTAGACATTTTTAGCCTTACCTGTATAAAGCAACTTATCTTCTGTCATAAATTTACACATCCCAAATTGAATTATTTTCAATAGCTTGCTTTGTAGCTTGTAAATCATCACTCAAAATCGTGATATGACCCATTTTGCGGTTATTTTTAACACTATCTTTGCCATAATCGTGGAAATGCCATTCTGGATGTTCAACTAACTCATTCTTAGCATTTTCCAAGTGTTGTCCGAGCAAGTTGACCATTGCGGCAGGTTTTAATAGCTCGACTTTTGGCATGGCAAGATTACAAACACCACGGATATGTGCATCGAACTGTGAAATGTTGCAGGCCTCAATCGTCAAGTGACCGGAATTATGTGGGCGTGGCGCAATTTCATTAACGAAAACTTCATCCGATTCTGAAATAAAGAATTCGATACACATTGTTCCGACCAACTCGAGATTATGAGCCAGCGTCTCACCAACTTGATAAATATGTTGCTCAGCTTTTTCGCTGATATCAGCTGGACAAGTACTGAGATGCAAGATGTTGTGACGGTGAACATTCTCAATAACAGGGAAAATTGATGTTTCACCACGAATGTTAGCAGATACGATAACTGAAACTTCTTTTTTCAGATCAATCTTCTTTTCCAACATACATGGTCCATGCATCAATAACTTTTCAATTTCGGCAAAATGAGCTTTCTCAGGGTCCTCAATCAAAATTTGACCTTTACCGTCATAACCACCACGAATTGTCTTCAAGATTACCGGAGCACCTAACTTTTCAACGCCTCGGTGATATTCAAAGATATTAGTAATTTCGATATGTGGCACCACTTTAAAACCGCTGGCTTCGATAAAGTTCTTTTCGGACACACGATTCTGAGTGGCTTTCAAAGCTTTGGTACCCTGTGGGACTTGAGTATATTTCTTAACTTCATTGATAGCATCAGCGTCGACATTTTCAAACTCATAAGTCAAAACATCACATTGCTTAGCCAACTCAATCAATTTATCAAGATCATCATATTCAGCGACAATTTGTCCATCTGACACTTGAGCAGCTGAACAATTTTCTTGCGGATCCAAAATGATGACTTTATAACCCATCTCTTTAGCTGAAAATGACATCATCTGGCCTAATTGACCACCACCGATAATGCCGATTGTTGCTCCTGGCAGTAACGTATTATCCAAGGTCTTTCCCACTTTCTACTGACTTATCGTGCATGGCTTGAACATATGCTGATAGATTATTTTGATAAGTTGGATTATTTAAAGCACAAATTTTTGTGGCGAGAATGGCTGCATTCTTTGCACCAGCCTCACCGATGGAAACTGTCGCAACTGGCACACCAGCTGGCATTTGAACAATTGATAGCAACGAATCCATTCCCTTGAGATATTTGGAAGGAACTGGAACGCCAATGACTGGCAAAGTTGTTGAAGAAGCAATCATTCCTGGTAAATGAGCTGCACCTCCAGCTCCAGCTATGATAACTTGATAATTTTCATGAGCATGATTGGCAAAGTCCAACATCTCATGTGGCATCCGATGTGCCGAAATTACTTTCGTTTCAAAACTAACTCCCAGTTCATTCAAAACATCGATTGTGTTCTGCATGATCTTCAAATCAGAAATTGAACCCATAACTATTGCTACGTCGTGCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP012559|1471235:1481237|1475776_1477987_-|WP_041499696.1|DBSCAN-SWA
MTEPTAKQIKDEKIYQQWGLTDSEYDLISTKILKRLPNYTETGLYSVMWSEHCSYKNSKKVLRKMPNKSERVIAGPGEDAGILDIGDNQAVVFKAESHNHPSAVEPYQGAATGVGGIIRDIFSMGAQPIALLNSLKFGPLKDGQTKHLVNEVVAGIGGYGNCIGLPTVGGEIAFEDCYEHNPLVNAMCVGLLNNTDFKHGTASGDKNLIVYVGAKTGRDGIHGATFASDEFTDTKNKQRSAVQVGNPFIEKLLMDACVEIIEKHPEWILGIQDMGAAGLVSSTAEMASKAGSGLVLNLDKVPQRETEMNAYEMMLSESQERMVLCVKPEFVDDVLAFFKHFELDAVVIGQVTTDKQYKIYHHDELVTDIPVDSLTEDVPEYDREETQPQRMIDDKDYQFVPVIDSLEKTWNEMLQRPNIASKKHFYQTYDSQVRANTLVRPGSDSGVVRIRGTRKAIAMTNDSNSKYVYLNPYVGGQIAVMEAARNIVASGGEPIGVTDCLNYGNPENPEAFWELDKSVEGIASACEKINTPVISGNVSLYNEYNDVAIYPSPMVGMVGLISDIDNVTTTAFKEAGDLIYVVGQTQDDFNGSELQMAQSGKLKGNLRNLDLDQEKLHQDIIRQAISQKLIMSCHDLSEGGLAVALSKSAFENELGFEINTSLTSAQMFSETQSRFLVTVAPENQTVFEELVATDIECLGTVTAAPEFKVTTADESVEINGLTAGKNWKEAIACLMK
>NZ_CP012559|1471235:1481237|1473354_1474374_-|WP_041499699.1|DBSCAN-SWA
MSNPYQDAGVNVESGYKISKFVKQNTHNSNIGNFGGVYEIPEGYKHPVLVSSDDGVGTKLLLTTEAKKWDTIGIDCVAMCVNDILAQGATPQYFLDYISTGKVDDKIEEILKGVIAGCNQANVNLIGGETAEMPGVYEAKDYDIAGFSVGICEKDDLLKKENIQAGNVLIGLKSSGIHSNGYSLVRKIFFQEHKLTVDSVLPEYTEQTLGALLLTPTKIYVQDIVPLLDERLIKGISHITGGGFYENIPRMLPDNLAAKINVDIWPKLPIFGLLQKYGQLETADMYHIFNMGIGMVITVDASKELEVLELLNEKETVAYTIGEVVPKSKESLILKGDQL
>NZ_CP012559|1471235:1481237|1480754_1481237_-|WP_041499688.1|DBSCAN-SWA
MHDVAIVMGSISDLKIMQNTIDVLNELGVSFETKVISAHRMPHEMLDFANHAHENYQVIIAGAGGAAHLPGMIASSTTLPVIGVPVPSKYLKGMDSLLSIVQMPAGVPVATVSIGEAGAKNAAILATKICALNNPTYQNNLSAYVQAMHDKSVESGKDLG
>NZ_CP012559|1471235:1481237|1474385_1475792_-|WP_041499698.1|DBSCAN-SWA
MPNEVRSLNEECGVFGVWGAENANYLTYLGLHSLQHRGQEGAGIVANDGKKLRAYRNLGLLTQVFSKPEYLNSLVGDSAIGHVRYSTAGENKIENVQPLLFDFTDSQIALAHNGNLTNAVTLKKELEEKGHIFKSSSDSEVLVHLIKVSNAPTFHEKIVEALNKIQGGFAYLLLTKDAMLVALDSHGFRPLSIGQLDNGAYVVASETCALDAVGAKLVRNVQPGELITIDNDGMKIDQWTTDTKLAICSMEFIYFARPDSDILGVNVHSARKRMGANLAKEFPALGDIVVGVPNSSLSAASGYAEASGLPYEMGLIKNQYMGREFIQPTQELREKSVRQKLAAVKGVVQGKRVILVDDSIVRGTTCAYIVQLLRDAGATEVHLRIASPRFMHPCFYGIDIQEKSELIAAHKSIPEMNEIFGSDSLKFLSEEGLIDAIGLKSDAPYSGLDMSYFNGDYPTYLYDYESRK
>NZ_CP012559|1471235:1481237|1478661_1478910_-|WP_041499693.1|DBSCAN-SWA
MKLVKVYVTLKDSVLDAQGEAIKSAVHSMGYNKVENVGMGKYFELKFADDYADLEKDVDSICDDLLANPNIETYRYEIAEAE
>NZ_CP012559|1471235:1481237|1477986_1478661_-|WP_041499694.1|DBSCAN-SWA
MKFAVINFPGSNCDMDLYYAIRDGIEQQVELVDYRAESLAGFDGVLIPGGFSYGDYLRSGAIAVHAPIVKEIIRFANEGKIVLGICNGFQILTELGLLPGALIKNEQGRFICETVALKVVNNQTAFTNGYEKDEVINIPIAHGEGRYYCDDKTLAELKANDQIAFQYLENVNGSVEHIAGVTNKQKNVLGMMPHPERAIEEILGSDDGLKLFQSIINYQVKVNN
>NZ_CP012559|1471235:1481237|1471235_1472777_-|WP_041499702.1|DBSCAN-SWA
MKRALISVSDKTGVVEFAKGLIANDFEIISTGGTYKKLQENGVKVTEIDEVTKFPEILDGRVKTLHPMVHAGLLAKRDNPEHMQTLEKLNIQTIDLVCVNLYPFKETISKDGVTPAEAIEQIDIGGPSMIRSASKNFKSVYVVIDASDYETVLESIKSDEDDTVLRRRLAAKAFRHTAEYDSIIAHYLTDLNGDEFPDVEVLGYDYHQELRYGENSHQKAAFYQSAMPSAYSIASAKQLHGKELSFNNIKDADAALRIVADFDQPCVAALKHMNPCGVGVDDECIYKAWHKAYTADTMSIFGGIVAVNREVTKEIAEEMHKIFLEIVIAPSFTDEALEILEAKKNIRLLTLDFSQAKAADKHEYVSVMGGLLVQERDTTVDQMDEFKVVTKKAPTDEEMKALLFGQQVVKHVKSNAIVITTTDKTLGIGAGQMNRIGSVKIAIEQEEKAETHSPLIMASDAFFPMDDCVQYAAEHGITAIVQPGGSIKDQDSIDMADKFGIAMVFTGRRHFKH
>NZ_CP012559|1471235:1481237|1478919_1479627_-|WP_041499691.1|DBSCAN-SWA
MTEDKLLYTGKAKNVYQAENDDEVLIVYKDQATALNGKKKEILPGKGVLDCQISQIVFNYLIENGIKTHLVKNLSDHEQLVKKTQVFPLEVVLRNITSGSLVRKFQIEEGQKLKEPIIEFYYKSDALDDPVINQSQIHALGIADNEDIEYIKQETLKINQLLIPFFAKADFDLVDFKLEFGKYNGEIILVDEFSPDNCRIWNKNDHHSMDKDVFRKHEGNLVETYQTVLQRLQDK
>NZ_CP012559|1471235:1481237|1479631_1480762_-|WP_041499689.1|DBSCAN-SWA
MDNTLLPGATIGIIGGGQLGQMMSFSAKEMGYKVIILDPQENCSAAQVSDGQIVAEYDDLDKLIELAKQCDVLTYEFENVDADAINEVKKYTQVPQGTKALKATQNRVSEKNFIEASGFKVVPHIEITNIFEYHRGVEKLGAPVILKTIRGGYDGKGQILIEDPEKAHFAEIEKLLMHGPCMLEKKIDLKKEVSVIVSANIRGETSIFPVIENVHRHNILHLSTCPADISEKAEQHIYQVGETLAHNLELVGTMCIEFFISESDEVFVNEIAPRPHNSGHLTIEACNISQFDAHIRGVCNLAMPKVELLKPAAMVNLLGQHLENAKNELVEHPEWHFHDYGKDSVKNNRKMGHITILSDDLQATKQAIENNSIWDV
>NZ_CP012559|1471235:1481237|1472773_1473358_-|WP_041499701.1|DBSCAN-SWA
MKVAIFASGNGSNFEAIAKSDELHNVGLEIELVVCDQKEAHVIERAAKYDIPVFINQLSDYPNRGAYEQAIIEKLKPLQIEYILLAGYMRVVTPVLLAAYPNHIINIHPSLLPKFSGLEAIERAFEAGDAVTGVTIHYIDEGVDTGPIIKQEKVVRLTNDTEESLEARIHQTEHQMYRQVILDLLNKTNGVDKK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041499702.1|1471235_1472777_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.8e-70	46.2
WP_041499701.1|1472773_1473358_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.9e-31	39.2
WP_041499699.1|1473354_1474374_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.1e-65	42.8
WP_041499698.1|1474385_1475792_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.1e-50	29.8
WP_041499696.1|1475776_1477987_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.2e-142	39.6
WP_041499694.1|1477986_1478661_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_041499693.1|1478661_1478910_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_041499691.1|1478919_1479627_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
WP_041499689.1|1479631_1480762_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_041499688.1|1480754_1481237_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.1e-22	43.7

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP012559|2593909:2604117|DBSCAN-SWA
AATGCAACAAGAATCACTTTTCGCAAGTCAAAATAAAGACGACAATTCACCTCTAGCCAATCGGGTTCGTCCCAAAACGCTAGAGGATTTTGTCGGTCAGCAACATTTAATCGGTGACAATAAAATTCTCCGTGACATCATTGATCAGGATAATATCCCCTCATTAATTTTTTGGGGACCTCCCGGGGTTGGTAAAACTACTCTCGCAGAAATTATTGCCAAGAAAACTGAAGCCAATTTCATCACCTTTAGTGCTGTCACTAGCGGTATCAATGATATTAAAAAAGTCATGAAAGAAGCTGAAATGAATCGTGAAATGGGACAAAAGACAATTGTCTTCATTGATGAAATCCATCGGTTCAATAAAGCCCAACAGGACGCTTTTTTGCCATTCGTTGAAAAAGGCAGCATCACCTTAATTGGAGCAACTACAGAGAATCCATCATTTGAAATCAATTCCGCTCTGTTATCACGTTGTAAAGTCTTTGTACTCAAATCTTTAACCACTGCCGACTTAGTCCAGTTACTACAAAATACGTTAAAGAATCCCAAAGTCTTTCCAAAATTAAAAGTTGAACTCGATTCCGATACTTTGGAATTAATCGCTGCTTATGCCAATGGTGATGCTCGAGTAGCCTTGAATACGCTAGAAATGGCCGTTATCAACTCTGAAACCAAGGACAAAGTTGCTTCAGTTAAAGCTGACGACGTCCGCCAATTGTTGAATACTAAGTCGCTTCGTTACGATAAAAATGGTGAAGAACATTACAACATCATCTCGGCTTTACACAAATCCATGCGTAACAGTGATACCGATTCAGCTATCTATTGGGTTATGCGTATGCTCGATGGCGGTGAAGATCCACTCTATATCGCCCGTCGGCTAGTCAGATTTGCCAGTGAAGACATCGGTTTGGCAGACACTAACGCTTTAAACGTGGCCATCAATGCCTTCCAAGCTTGCCAATTCCTAGGAATGCCTGAATGTAACGTTCATTTGGTAGAAACTGTGATCTATTTATCAGTCGCACCTAAATCAAATGCCGTTTATAAATCAGTTTTAGCCGCTGAAAAAGATATTAAGAAATATGGTAACTTGCCAGTTCCATTGCAGATTAGAAATGTACCAACTAAGCTAATGAAGAATCTCGGTTATGGTAAAGATTATGAATTAGCCCACAACTATCAAGACAAATTAACAACCATGCAAACTGTTCCTGATGAAATCAAGGATAGTCAATATTACCACCCTACCGAACAAGGTAAGGAGCGACTATTCAAGCAACGTTTGGAATATGTCAAACAATGGCACCAAGAACACGATGATAAATAACAAAAAACGACCAAGTAATCAAATTTACAGATTACTTGGTCGTTTTTTGTTCAAATTATAAATCTTCTTTTTTAATATGTTTTACATTATCGCCGCTTGCTAAAAGAGCATCAGTCACAACATCTTTAAAATATGATGTTCCCAAAACTCCTGCCATTACTGCTAATTTACTATTAATCGAGTCAATTTCGGACCAATCTTTAAAATGACAGTCAACTAAGCCATTGCCATTAGGTGTTCGTACCATTCCAGCCATATCTTGAGATTGACGAACTTCTGCTTCTCCACCCAACTGAGAAACTGTATCTATAACTTGTGGGATAGCCATTTCTAGCACTTCCAACGTCAATTGCACATCAGGATTCAATGCTTCAGCAAATCGCTCCTGTGGCGCCATAATAACGTATCGGTCAGCCAAATTAGCATATAAGCGTTCCAAAGTATGGATGCCACCGCCACTTTTCAAAACATTCAGGTTTTGGTCGATACTATCGCAACCGTCAAAGGCTAAATCAAATTTCGTTACTTGTTCCAAAGGTACAACCGGAATATTCAATTCCAGACAAAGCTTTCGAGTTTGTTCTGAAGGACTAGCCACTTTAATTGTTGATGCATCCAAAGCGTGAATCAAGCGTCCTACCGTGCGACCGCCACCAAAACTAACAGTCATACCAGGCTTGATCATTGTTAAAGCCGATTCGATTAATTTTTCCATGTTTACATCCTCGTAAGAAATATATTTTGCATGCATTTAATTCAACACTTATTCTATCAAAAATTCTGCAGCAAAAAAGCCTGCTAATAAGCAGGCCATCATGATATTCAATAGTAGGATAAATATCAACTTCTTTCTTTTGAAGATTAACTACGGGGGAATAGTAATCTTGAATTTAACTTCTTTATCTATTAGGGGGAGATATCTGAAGTTTAAGTTTATTTATAGGAGATTAAATTTTTATTCGTATATATATGTTTTAAGGGGGTTATTTCTATTCATTAATTGTTTTCAATAATTGTTTTTTAAAGGGTTTGTTCTATTTGAAGCTTTATCTAATCATCCGTTCACCTCTTCCTCTATTTGACTATGTTTAAATAATAACGTTTAAATACGAATAAATTTATAACAAAATATGAAGAATTGGTGAATTATTTTCCGTCTCCAGAGCTAAGAAGTATTCATCTGCTATGCGGACCGGGCCGAGCCAAGGTCTCGTCCCTCGGTTTGAAGGCTTTCCAAAGACCGGAAAGTCTCCAAACTCGCCCGGTGGTGTAAGAGCTAAAGCTCTAACGCCACACCCACAGCGGGTGAATACTTCTTAGCTCTTCCGTCTCTTTTGTTACTGCAGTGGATATGAAATAGTCTGTATATCTTATCAAATTGATTAAATCCTCTGATCTTCCTAGCTTTTATAGGAATTCAAAGATATATAGAAACACCTCTAAATTCCATCATATATATCGAAGAAAATAGAAGAGCAAAATTCTTTTTAAAACCCTAGCTTCCGGTTTCCAGTTATGGAGGCTGCTGTGGAAGTGGAGTTAGGACGAGCGTTCTTCTCGTTCTTACTCCACAGGACGACTTTTGAGACGCGGTTTTCGGCTCAAAATCGAGGGTCGAGACCGCACTTCGGCTCGAGCCGGTCCCATAGCTGAACTCCATAACTGGAAACCGGAAGTGGCATCCTTCAATAACATACAAAAAAAGGACTGCCCTTTCTTTCGGACAGTCCAACGTGAATGATTTTAATTTTGAATGTGTATTATAGAACTTTAACAGCGAATGAAGGCATGAAGTAGCCTGAGATTGTTGAAATCTTAACTGATTCGCCTGGTTGTGGTGCGGCGATGTATTGGTTGTTACCTAAGTAGATACCTACGTGGTAAGTTGAACCTTTGCCACCCCAGAATAATAGATCTCCAGCTGATGCTTGAGAAACTGCTTCTTGTGTACCGGCACTTTCTTGAGCTACTGTATATGAACCAATGCTCTTACCAGTTGCTTGTTGGTATACGTATGATGTGAAACCTGAACAGTCGAAACCTGAAGGTGTCTTACCACCCCATACATATGGTGTACCGATATATTTCTTAGCAGTATTTACAACACTGTCAGAAGTTGAAGCTTTGTCTGATGATGAAGCTGATTCTGTAACAGCAGCCATATCAGTAACGTCACTAGCGTTAACCCATTCACTTGCGCCTACTAGGTACCATGTGTTTCCTTGATCGTCTTTAACAGCTTGACCAACGGCCCAGGCTGTATTAGCTTGCAATGCACGGCCAGAACTCTTGCCATTTGATGATGGTGTTGTGTAAAGTGCTGACATTGTCTTTGTACGTACAGCAGAAGGTGCATCAGATAGAACTTGTGAAGCAGCCTTTGTTGTAGAAGCATTTGATAGGCCTAAACCTGTAACTGCTAAAGCGGCAGCAGCTGTAAATGAAATAAGACTCTTTTTAACGTTAGTATTCAAAATTGAAATCCCCCGTAATGGTTTGTTTTTTTTATTTTTTAAGTTTTTCTTAATTATTAATTTCTTATCACTCAACGTTGACTATAATACGCTCTGAATATTGCAGAAATGTTACAGCAATTGTATAAGAATGTTACACTTTGTTGTTCACAAAGTAATAAAGCTGTAACCACATACATATCAGTGGTTACAGCTTTATTGTGAAAAACTCATTTACTTGATTTTTTCGATATTCAGTATTTTGTTAACGCTTTCCTTAGTTATTTCTATGTTATTATTAGTAATTTTATAACATTTACCCCTTAATTCACTCGGAATATTCAAATCTCGATGGAATTCGTCACTATTAATTCGCGCCTTTAATCGATTAATATCATCCCCGCGACCAGCCAAACGTTTCGTCACAGTATCCAAATCTACTTCAAGAAAAATGACGACTGCCTGATTGCCATACTTCTCTTTATAGGAAATTGCACCTTTAGTATCGACCACAATACTGGCCGCATCATACTTTTCCCAAGTTTTATTGAGACTTTCTTCAGAAGATCCATACCAATTGCCACTAAATTCGACTCTTTCGAGATAATGATTCTTCAAAAAGCTATCTTTCGTCTCAAAATGATAGTCTATGCCGTCTTTTTCGCCCACACGTGGTAATCTAGTAGTATGAGTTATGACACTCGGTATATGATAGGTATCTTGCAAATATTTACTAATTGTTGTTTTCCCAGTTCCACTTGCTCCAGTGATAACAATAATTTTTTTATCCATTATAGGACTCCTATGTTTGAAATATTTCTTCTACTATATTATTATACTAGTCTGTTAAGTAATTAATCCGAGGAGAATTAGATATGAAAATAGAAGACTTAAAAGTTGGCACTGTTTACGATTGCTCCGTTGATGAAGATATGGATTACCCATTCCAAGGAAAAGTTGAGAAAGTTTACGAGCACTCAGCTTTGATGGAGATTGTTAAGAATGATCCTAAGGACAATACTAATAAAACGGAATTAAATAACAAGATTGTTGTAAGTATCAAGAAAATCAAAAAAGCTAAATAATTAATCTCATAAAAAGAAGCCGGTCATTAAGTTGATCAGCTTCTTTTTTTTACTCTTCGTTATATTAGTCTGCCGTTTCCAGAGCTGAGAGTATTCATCTGTTGCGCGGCACGGTCCGAGCCAAAGTGCGGTCTCGGGCCTCGGTTGAAGACTTTCCAAAAATCGGAAAGTCTCCAACACGTCCGGTGGTGTAATTGCTAAAGCAATAACGCCACTTTCGCTACGGATAAATACTCTCAGCTCTTCCAACTAATTTAATTTTTTAATTTAAAAACATCCCTTAATTTGCGGCTAGATTTTTTTGATTATGGTTTAATTATTTACATCATTGATGTAATGAATAGAGAAGACAATTATCAGACTCTCTGAACCATCCGTATTCAATTAAATATCGAATAATCGGATTCCTACCTTCAATTACACATCAATAAACTAAAACCCTAGCCTCCGGTCGTCAGTGATTTTTGCCTGCCATGGAGGTGGCGTTATTGCTTTAGCAATTACACCACGGGACGAGCTTGGAGACTTGCGGTTTTTGCAAGTCCTCAAATCGAGGTTCGAGACCGCCCTTTGGCTCGGACCGGTCCCCATAGCGGCAAAAAATCACTGACGGCCGGGGCGGCCGCCTTTACAAACATCTATTTTTCAACATTAATAAATGAACGTGCAGGAACTCGTAATACTCGATATTCCATTGCATAACGGTTAGCTTTTAGACCTAAGCCGTTGATGAAGTTGTTCTTATACTTGGCACGAACGGTAATAACGTATGCGTCTTGATACTTACTATCGGCCTTCTTGATTTTCTTCATTGGCCAATCCAAATGCATGCCTGATACGGTGAATGGCAATGTTGCATCTGAGATTGTGGCATTTCGACTGGAAACTGTGAATGTCGAATTATTGATCCAATATTGGTAGACATCTGTTGCGGTATTGGATTCTTTCTTATCGATCTTGACGTAATATCCTTGACCATCATTGGTTGTCTGCACAATCATCGGATCGTACTTATATGAAACGGCGACTTCACTTTTATCAGTCAAATCAACTTTTGTAAACAAACTCGTGTACAACATACCACTGACAGCAAAAATAACGACCAGGATTTCAACAAAGTCCATCAAAATCGTTGCTCCAGTAATTTTTCCCTTTTTAACTACTAAAATTTTTAAATGGCGATTTCTAATATTAAATACTACAAAGATTAATAGCGCGATGACAATAATCCATGCAATAATTCCCACAAAATTCCAAGAACTCATAGTTTTCTCCCAACTAAAATTGATTGTTTTACACACTTCATAACTCTATAATAGTCATTACGCTAATTTTACCACGAATCGAAAAATTATTTGAAATTGAGATGCGAAACGCTAAAAAATGTGTGGGTACACACGTTTGCCGACTTTTTATAATGGTAGCATAACCACGCTATATCGTGTGTTCACCGTTATGTCGAATACAATATATTGTGTTTCGTATTTCAAATGATTATACTAATTGAGAATAGCACTTGAGAGGAAGTAATAACATGAACAACACAATCGTATATAGTAAAAATAACTGCATGCAATGCAAAATGACTAAGAGATATCTTAAAGAACACAACGTTCCTTTTGAAGAAAGAAACATCAATCAAGACCCTGAATTTTTAGCCACTCTTAAACAACAGGGATTCCAAAGTGTTCCTGTCGTAATGAACTCAGCTATGGACCCAATCGTCGGTTTCCGTCCAGATAGCCTAAAGGAGCTCGTGGACTAATGAAAGAGCTAGCTTATTATTCAATTACAGGTCAAACAAAGCGTTTTGTTAATAAGCTGGGAATAGATGGATATGAAATTACCGATGCCGATCCGTTTTATCAAATGGGTCGGCCATTTATTCTTATTGTGCCTGCTTATGACGACGATATGATGGACCCTGTAATCGATTTTCTCCAATATGAAGACAATGCCAAGAACTGTGTCGGTGTCGCCGGTGGTGGCAATCGTAACTTCAATACGCTCTACAATCATACGGCTAAGGATATCGCCGCTGGTTTAAATGTGCCCGTTGTCTTCCAATTTGAATTCAATGGTACCCAAAAAGATGTCGAAAACTTTCAGAAAGTAGTGAATGAAATTGGGATTAAATAACCTCGATGCAACTAAGCTTAGTTATTTCAAATTAAATAACGAAATCAACATCCCCGTAGATGGCAAAATTCCACTAAACAAGGATAAAGAAGCTGTTGCAGCCTTCTTTGCCGAAAATGTGAAACCTAATACGATGAAGTTTGATACTTTCCAAGACCACCTAGATTACCTAATCAAAGGTGACTTCATCGAAAAATCAGTTATCGATAAGTACTCAGTTGAATTTATCGAAAATCTTTACCAATACTTGTTGGATCAACATTTTGAGTTCCAATCATTTATGGCAGCCTATAAGTTTTACAATCAATATGCCCTAAAGACTAACGATGGTAACTATTATCTTGAAAATTATGAGATGAGAATTCTTTTTAATGCCCTTTTATATGCCAATGGCGACCAAGATCTCGCAAAGAGTTTGGCAACTGAGATGATTGCTCAGCGTTATCAACCCGCTACACCGTCATTTTTAAATGCTGGTCGTAAGCGCCGTGGTGAATACGTTTCTTGTTTCTTACTACAAGTTACTGACGATATGAACAGTATCGGTCGAACAATCAACAGTGCCTTACAACTATCACGTATCGGTGGTGGTGTTGGTATTACCCTATCGAACTTGCGTGAGTCAGGTTCTCCTATTAAAGGTGTCGACAATTCATCATCCGGTGTTTTGCCCGTTATGAAGTTATTGGAAGACAGTTTCAGTTACAGTAACCAACTCGGTCAAAGACAAGGTGCTGGTGCCGTTTATTTGAACGTTTTCCATCCTGATATTATTGAGTTTCTATCTGCTAAAAAAGAAAACGCTGACGAAAAGGTTCGTGTTAAGACTCTTTCACTCGGCGTTATCGTACCTGATAAATATTATGAATTAGTTCGCAACAACGAACCGATGTATCTCTTCAGCCCTTATTCAGTTGAGCGCGTCTATGGCAAACCATTCTCATATATCGACATCACTAAAGAATATGACAACCTGGTTAAAGACGACCGCATTAAGAAATATAAAATTGATGCGCGTGAGCTTGAAGATGAAATTAGTAAACTTCAACAAGAATCTGGTTACCCATACGTCCTAAATATCGACACCGTTAACCGTACAAATCCTATCGACGGTAAGATTATCATGAGTAATCTTTGTACTGAAATTCAACAAGTCCAAATCCCTTCTGAATTAAATGATGCTCAAGAATATACTAAATTGGGAACAGATGTCAGCTGTAACCTTGGTTCAACTAACATCTTGAATATGATGCAAAGTCCTGACTTCGGTCAATCGATTCGTTCAATGACTAGAGCTTTGACATTTGTCAGTGATGCTTCAAATATCACATCTGTTCCACCAGTTGCTAATGGTAACAAGATGAGCCATGCCATCGGATTGGGCGCTATGGGATTACATACCTTTTTAGCTTGCCATCATCTCGAATATGGCTCACCAGAAGCAATTGAGTTCATCAACGTTTACTTCATGTTGCTAAATTACTGGACTTTAGTTGAAAGTAACAACATTGCTAAAGAACGTCATGAAACTTTCGCTAACTTTGACAAATCTAAATACGCTGACGGAACTTACTTCGATAAATATGTCGAAAATAACTACGCTCCAAAATTAGATAACGTTAAAGAACTCTTCGCCGGTATCTTTATTCCTGAAGAAAAAGACTGGGCTGCATTAAAAGACAGCGTTATGACGGATGGTATCTATAACGCCTACCGTATGGCAGTTGCCCCTACTGGCTCAATTTCTTACATCAATAACACTAGTGCCAGTTTGCAACCCGTTACACGTCTAGTTGAAGAGAGACAAGAAAAGAAGAACGGTAAGTTATACTTCCCAGCTCCTTTCTTGAGTAACGATACAATCAAATATTACAAGTCAGCCTATGACACCGATATGCGTAAAGTTATCGATACATACGCTTCAGCCCAAGAACACATCGATCAAGGTATGAGTTTGACCCTATTCATGCGTTCCGAAATCCCAGCAGGACTATATGAATGGAAAGCTGCTGACGATACTAAACAGACAACACGTGACCTAAGTATTTTGCGTAACTACGCTTACTACAAGGGTATCAAGTCACTTTATTATGTGAGAACATTTACCGAGAACAATGATGAAATCGGCAGTAACGAGTGTGAAAGCTGCTCAATCTAGGAGGAATTTTTTATAATGGTTGATACATATTACAAATCAATGAACTGGAATAAACTTGAAGACCAAATCGACAAGGAAACTTGGGAAAAGTTAACTTCTCAATTTTGGTTGGATACTAGAATCCCTCTTTCAAACGATTTAGACGATTGGCGCACCTTGAATTCCGCTGAACATACCGTTGTCGGACACGTCTTTGGTGGTTTAACACTCTTAGATACATTACAGTCACAAGATGGTATCCAAGCAATGTTAAAGGACACTCGTACTCAAGCCGAAACTGCCGTTTTCAATAACATTGAATTTATGGAATCAGTTCATGCCAAGAGTTACTCATCAATCTTCAGTACTTTAAACAGTGCCGAAGAAATTGAGGAAATTTTCGACTGGACTGATCACAACGAATATCTTCAAAAGAAAGCTAAGTTTATCAACGATATTTATCAAAATGGTGAACCATTGCAGAAAAAAGTTGCCAGTGTCTTTCTAGAAAGCTTCTTATTCTATTCTGGTTTCTACACACCACTTTACTATCTTGGTAACAACAAATTAGCTAACGTTGCAGAAATCATCAAGTTGATCATTCGTGACGAATCGGTCCACGGAACTTATATCGGTTATAAATTCCAACTCGGTTTTAACGAATTGAGCGATGATAAAAAGGCTGAATTGAAAGACTGGATGTACGATTTGCTCTATACTCTCTATGATAATGAAGAGAAATATACTCGTGAATTGTACAAAGAGGTTGGTTGGGTCGATGAAGTTCTAGTATTCCTTCGTTATAACGCTAACAAAGCATTGATGAACCTCGGTCAAGAGCCACTATTTCCAGATGGCAATGCCGAAGATGTCAATCCTATCGTTATGAACGGTATCTCGACTGGTACAAGTAATCATGATTTCTTCTCACAAGTTGGTAATGGTTATTTGATGGGTAAAGTTGAAGCCATGCGAGATTCTGATTACGATATTGGGCGTACTGGCGACAATAAGACACCTGATGGTAATTCATTGTTTGATAAGGTTAAAAAATTAAAATAA

Protein sequences of DBSCAN-SWA_2

>NZ_CP012559|2593909:2604117|2600313_2600544_+|WP_041500351.1|DBSCAN-SWA
MNNTIVYSKNNCMQCKMTKRYLKEHNVPFEERNINQDPEFLATLKQQGFQSVPVVMNSAMDPIVGFRPDSLKELVD
>NZ_CP012559|2593909:2604117|2598569_2598779_+|WP_041500347.1|DBSCAN-SWA
MKIEDLKVGTVYDCSVDEDMDYPFQGKVEKVYEHSALMEIVKNDPKDNTNKTELNNKIVVSIKKIKKAK
>NZ_CP012559|2593909:2604117|2600543_2600918_+|WP_041500353.1|DBSCAN-SWA
MKELAYYSITGQTKRFVNKLGIDGYEITDADPFYQMGRPFILIVPAYDDDMMDPVIDFLQYEDNAKNCVGVAGGGNRNFNTLYNHTAKDIAAGLNVPVVFQFEFNGTQKDVENFQKVVNEIGIK
>NZ_CP012559|2593909:2604117|2597001_2597568_-|WP_082330719.1|DBSCAN-SWA
MSALYTTPSSNGKSSGRALQANTAWAVGQAVKDDQGNTWYLVGASEWVNASDVTDMAAVTESASSSDKASTSDSVVNTAKKYIGTPYVWGGKTPSGFDCSGFTSYVYQQATGKSIGSYTVAQESAGTQEAVSQASAGDLLFWGGKGSTYHVGIYLGNNQYIAAPQPGESVKISTISGYFMPSFAVKVL
>NZ_CP012559|2593909:2604117|2600898_2603076_+|WP_169751891.1|DBSCAN-SWA
MKLGLNNLDATKLSYFKLNNEINIPVDGKIPLNKDKEAVAAFFAENVKPNTMKFDTFQDHLDYLIKGDFIEKSVIDKYSVEFIENLYQYLLDQHFEFQSFMAAYKFYNQYALKTNDGNYYLENYEMRILFNALLYANGDQDLAKSLATEMIAQRYQPATPSFLNAGRKRRGEYVSCFLLQVTDDMNSIGRTINSALQLSRIGGGVGITLSNLRESGSPIKGVDNSSSGVLPVMKLLEDSFSYSNQLGQRQGAGAVYLNVFHPDIIEFLSAKKENADEKVRVKTLSLGVIVPDKYYELVRNNEPMYLFSPYSVERVYGKPFSYIDITKEYDNLVKDDRIKKYKIDARELEDEISKLQQESGYPYVLNIDTVNRTNPIDGKIIMSNLCTEIQQVQIPSELNDAQEYTKLGTDVSCNLGSTNILNMMQSPDFGQSIRSMTRALTFVSDASNITSVPPVANGNKMSHAIGLGAMGLHTFLACHHLEYGSPEAIEFINVYFMLLNYWTLVESNNIAKERHETFANFDKSKYADGTYFDKYVENNYAPKLDNVKELFAGIFIPEEKDWAALKDSVMTDGIYNAYRMAVAPTGSISYINNTSASLQPVTRLVEERQEKKNGKLYFPAPFLSNDTIKYYKSAYDTDMRKVIDTYASAQEHIDQGMSLTLFMRSEIPAGLYEWKAADDTKQTTRDLSILRNYAYYKGIKSLYYVRTFTENNDEIGSNECESCSI
>NZ_CP012559|2593909:2604117|2595296_2595956_-|WP_041500343.1|DBSCAN-SWA
MEKLIESALTMIKPGMTVSFGGGRTVGRLIHALDASTIKVASPSEQTRKLCLELNIPVVPLEQVTKFDLAFDGCDSIDQNLNVLKSGGGIHTLERLYANLADRYVIMAPQERFAEALNPDVQLTLEVLEMAIPQVIDTVSQLGGEAEVRQSQDMAGMVRTPNGNGLVDCHFKDWSEIDSINSKLAVMAGVLGTSYFKDVVTDALLASGDNVKHIKKEDL
>NZ_CP012559|2593909:2604117|2597928_2598486_-|WP_041500346.1|DBSCAN-SWA
MDKKIIVITGASGTGKTTISKYLQDTYHIPSVITHTTRLPRVGEKDGIDYHFETKDSFLKNHYLERVEFSGNWYGSSEESLNKTWEKYDAASIVVDTKGAISYKEKYGNQAVVIFLEVDLDTVTKRLAGRGDDINRLKARINSDEFHRDLNIPSELRGKCYKITNNNIEITKESVNKILNIEKIK
>NZ_CP012559|2593909:2604117|2599417_2600044_-|WP_041500349.1|DBSCAN-SWA
MSSWNFVGIIAWIIVIALLIFVVFNIRNRHLKILVVKKGKITGATILMDFVEILVVIFAVSGMLYTSLFTKVDLTDKSEVAVSYKYDPMIVQTTNDGQGYYVKIDKKESNTATDVYQYWINNSTFTVSSRNATISDATLPFTVSGMHLDWPMKKIKKADSKYQDAYVITVRAKYKNNFINGLGLKANRYAMEYRVLRVPARSFINVEK
>NZ_CP012559|2593909:2604117|2603091_2604117_+|WP_041500354.1|DBSCAN-SWA
MVDTYYKSMNWNKLEDQIDKETWEKLTSQFWLDTRIPLSNDLDDWRTLNSAEHTVVGHVFGGLTLLDTLQSQDGIQAMLKDTRTQAETAVFNNIEFMESVHAKSYSSIFSTLNSAEEIEEIFDWTDHNEYLQKKAKFINDIYQNGEPLQKKVASVFLESFLFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSDDKKAELKDWMYDLLYTLYDNEEKYTRELYKEVGWVDEVLVFLRYNANKALMNLGQEPLFPDGNAEDVNPIVMNGISTGTSNHDFFSQVGNGYLMGKVEAMRDSDYDIGRTGDNKTPDGNSLFDKVKKLK
>NZ_CP012559|2593909:2604117|2593909_2595241_+|WP_041500341.1|DBSCAN-SWA
MQQESLFASQNKDDNSPLANRVRPKTLEDFVGQQHLIGDNKILRDIIDQDNIPSLIFWGPPGVGKTTLAEIIAKKTEANFITFSAVTSGINDIKKVMKEAEMNREMGQKTIVFIDEIHRFNKAQQDAFLPFVEKGSITLIGATTENPSFEINSALLSRCKVFVLKSLTTADLVQLLQNTLKNPKVFPKLKVELDSDTLELIAAYANGDARVALNTLEMAVINSETKDKVASVKADDVRQLLNTKSLRYDKNGEEHYNIISALHKSMRNSDTDSAIYWVMRMLDGGEDPLYIARRLVRFASEDIGLADTNALNVAINAFQACQFLGMPECNVHLVETVIYLSVAPKSNAVYKSVLAAEKDIKKYGNLPVPLQIRNVPTKLMKNLGYGKDYELAHNYQDKLTTMQTVPDEIKDSQYYHPTEQGKERLFKQRLEYVKQWHQEHDDK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041500341.1|2593909_2595241_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	6.6e-90	42.5
WP_041500343.1|2595296_2595956_-	ribose-5-phosphate isomerase A	NA	NA	NA	NA
WP_082330719.1|2597001_2597568_-	C40 family peptidase	A0A0A8WIF2	Clostridium_phage	4.5e-16	39.8
WP_041500346.1|2597928_2598486_-	AAA family ATPase	A0A212Q4J6	Cowpox_virus	1.9e-11	33.1
WP_041500347.1|2598569_2598779_+	hypothetical protein	NA	NA	NA	NA
WP_041500349.1|2599417_2600044_-	hypothetical protein	NA	NA	NA	NA
WP_041500351.1|2600313_2600544_+	glutaredoxin-like protein NrdH	X2KRY7	Enterococcus_phage	4.0e-11	45.9
WP_041500353.1|2600543_2600918_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	2.2e-11	34.2
WP_169751891.1|2600898_2603076_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	7.6e-253	59.4
WP_041500354.1|2603091_2604117_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	2.6e-118	64.9