CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP010849	Streptomyces cyaneogriseus subsp. noncyanogenus strain NMWT 1 chromosome, complete genome	21 crisprs	csa3,DEDDh,WYL,cas4,Cas9_archaeal,cas3,DinG	11	11	5	1

1. NZ_CP010849

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP010849_1

• CRISPR_ID: NZ_CP010849_1
• CRISPR_location: 238093-238171
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_1

Consensus_repeat	Method
GGGGCCGGGGGCGGGGCGAGCGCC	CRISPRCasFinder

spacers of NZ_CP010849_1

>1.1|238117|31|NZ_CP010849|CRISPRCasFinder
AGGGGCAGGGCGGGCGCCCGGGGGCAGGGTG

CRISPR arrays and Neighbor proteins around NZ_CP010849_1

CRISPR arrays

The CRISPR arrays of NZ_CP010849_1

>merge|NZ_CP010849|1|238093-238171|CRISPRCasFinder
GGGGCCGGGGGCGGGGCGAGCGCCAGGGGCAGGGCGGGCGCCCGGGGGCAGGGTGGGCGCCGGGGGCAGGGTGGGCGCC

>NZ_CP010849|1|1|238093-238171|CRISPRCasFinder
GGGGCCGGGGGCGGGGCGAGCGCC	AGGGGCAGGGCGGGCGCCCGGGGGCAGGGTG
GGCGCCGGGGGCAGGGTGGGCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044378243.1|234739_235420_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP010849.1|WP_044378236.1|225831_226941_+|AfsR/SARP-family-transcriptional-regulator	unknown	unknown	gnl|CDD|276938
NZ_CP010849.1|WP_044378247.1|237255_237489_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044378264.1|251897_252176_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044378261.1|247582_248590_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NZ_CP010849.1|WP_044378256.1|243589_245593_+|acyl-CoA-oxidase	unknown	unknown	gnl|CDD|173839
NZ_CP010849.1|WP_044378251.1|239299_240535_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP010849.1|WP_044378263.1|250326_251547_+|amidohydrolase	unknown	unknown	gnl|CDD|349882
NZ_CP010849.1|WP_107071132.1|228134_229436_-|hypothetical-protein	unknown	unknown	gnl|CDD|380465
NZ_CP010849.1|WP_044378258.1|245637_246261_-|DUF998-domain-containing-protein	unknown	unknown	gnl|CDD|377627
NZ_CP010849.1|WP_044378249.1|238536_238827_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044378245.1|235514_237107_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_CP010849.1|WP_044378238.1|231717_232539_-|AfsR/SARP-family-transcriptional-regulator	unknown	unknown	gnl|CDD|276938
NZ_CP010849.1|WP_078968997.1|227124_228336_-|hypothetical-protein	unknown	unknown	gnl|CDD|380465
NZ_CP010849.1|WP_044378241.1|233663_234485_-|AfsR/SARP-family-transcriptional-regulator	unknown	unknown	gnl|CDD|276938
NZ_CP010849.1|WP_044378259.1|246448_247411_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044387236.1|230199_231156_-|cyclase	unknown	unknown	gnl|CDD|176870
NZ_CP010849.1|WP_044378253.1|241534_242236_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP010849.1|WP_044378234.1|224983_225730_+|thioesterase	unknown	unknown	gnl|CDD|225749
NZ_CP010849.1|WP_044378262.1|248733_250161_+|MFS-transporter	unknown	unknown	gnl|CDD|129794

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044378243.1|234739_235420_-|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.20626e-09
NZ_CP010849.1|WP_044378236.1|225831_226941_+|AfsR/SARP-family-transcriptional-regulator	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	2.019e-48
NZ_CP010849.1|WP_044378261.1|247582_248590_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	2.15161e-20
NZ_CP010849.1|WP_044378256.1|243589_245593_+|acyl-CoA-oxidase	gnl|CDD|173839	cd01150, AXO, Peroxisomal acyl-CoA oxidase. Peroxisomal acyl-CoA oxidases (AXO) catalyze the first set in the peroxisomal fatty acid beta-oxidation, the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. In a second oxidative half-reaction, the reduced FAD is reoxidized by molecular oxygen. AXO is generally a homodimer, but it has been reported to form a different type of oligomer in yeast. There are several subtypes of AXO's, based on substrate specificity. Palmitoyl-CoA oxidase acts on straight-chain fatty acids and prostanoids; whereas, the closely related Trihydroxycoprostanoly-CoA oxidase has the greatest activity for 2-methyl branched side chains of bile precursors. Pristanoyl-CoA oxidase, acts on 2-methyl branched fatty acids. AXO has an additional domain, C-terminal to the region with similarity to acyl-CoA dehydrogenases, which is included in this alignment.	1.88844e-55
NZ_CP010849.1|WP_044378234.1|224983_225730_+|thioesterase	gnl|CDD|225749	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	9.90161e-50
NZ_CP010849.1|WP_044378263.1|250326_251547_+|amidohydrolase	gnl|CDD|349882	cd03886, M20_Acy1, M20 Peptidase Aminoacylase 1 family. Peptidase M20 family, Aminoacylase 1 (ACY1; hippuricase; acylase I; amido acid deacylase; IAA-amino acid hydrolase; dehydropeptidase II; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14) subfamily. ACY1 is the most abundant of the aminoacylases, a class of zinc binding homodimeric enzymes involved in the hydrolysis of N-acetylated proteins. It is encoded by the aminoacylase 1 gene (Acy1) on chromosome 3p21 that comprises 15 exons. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney, suggest a role of the enzyme in amino acid metabolism of these organs. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D), resulting in a metabolic disorder manifesting encephalopathy and psychomotor delay.	8.54052e-129
NZ_CP010849.1|WP_107071132.1|228134_229436_-|hypothetical-protein	gnl|CDD|380465	cd19543, DCL_NRPS, DCL-type Condensation domain of nonribosomal peptide synthetases (NRPSs), which catalyzes the condensation between a D-aminoacyl/peptidyl-PCP donor and a L-aminoacyl-PCP acceptor. The DCL-type Condensation (C) domain catalyzes the condensation between a D-aminoacyl/peptidyl-PCP donor and a L-aminoacyl-PCP acceptor. This domain is D-specific for the peptidyl donor and L-specific for the aminoacyl acceptor ((D)C(L)); this is in contrast with the standard LCL domains which catalyze peptide bond formation between two L-amino acids, and the restriction of ribosomes to use only L-amino acids. C domains of nonribosomal peptide synthetases (NRPSs) catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). There are various subtypes of C-domains in addition to the LCL- and DCL-types such as starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity.	4.08767e-34
NZ_CP010849.1|WP_044378258.1|245637_246261_-|DUF998-domain-containing-protein	gnl|CDD|377627	pfam06197, DUF998, Protein of unknown function (DUF998). Family of conserved archaeal proteins.	1.39167e-13
NZ_CP010849.1|WP_044378253.1|241534_242236_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.53301e-13
NZ_CP010849.1|WP_044378245.1|235514_237107_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP010849.1|WP_044378238.1|231717_232539_-|AfsR/SARP-family-transcriptional-regulator	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	1.04241e-60
NZ_CP010849.1|WP_078968997.1|227124_228336_-|hypothetical-protein	gnl|CDD|380465	cd19543, DCL_NRPS, DCL-type Condensation domain of nonribosomal peptide synthetases (NRPSs), which catalyzes the condensation between a D-aminoacyl/peptidyl-PCP donor and a L-aminoacyl-PCP acceptor. The DCL-type Condensation (C) domain catalyzes the condensation between a D-aminoacyl/peptidyl-PCP donor and a L-aminoacyl-PCP acceptor. This domain is D-specific for the peptidyl donor and L-specific for the aminoacyl acceptor ((D)C(L)); this is in contrast with the standard LCL domains which catalyze peptide bond formation between two L-amino acids, and the restriction of ribosomes to use only L-amino acids. C domains of nonribosomal peptide synthetases (NRPSs) catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). There are various subtypes of C-domains in addition to the LCL- and DCL-types such as starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity.	2.47895e-25
NZ_CP010849.1|WP_044378241.1|233663_234485_-|AfsR/SARP-family-transcriptional-regulator	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	5.8895e-53
NZ_CP010849.1|WP_044387236.1|230199_231156_-|cyclase	gnl|CDD|176870	cd08861, OtcD1_ARO-CYC_like, N-terminal and C-terminal aromatase/cyclase domains of Streptomyces rimosus OtcD1 and related domains. This family includes the N- and C- terminal aromatase/cyclase (ARO/CYC) domains of Streptomyces rimosus OtcD1 and related domains. It belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. ARO/CYC domains participate in the diversification of aromatic polyketides by promoting polyketide cyclization. They occur in two architectural forms, didomain and monodomain. Didomain aromatase/cyclases (ARO/CYCs), contain two ARO/CYC domains, and are associated with C7-C12 first ring cyclized polyketides. Streptomyces rimosus OtcD1 is a didomain ARO/CYC. The polyketide Oxytetracycline (OTC) is a broad spectrum antibiotic made by Streptomyces rimosus. The gene encoding OtcD1 is part of oxytetracycline (OTC) gene cluster. Disruption of this gene results in the production of novel polyketides having shorter chain lengths (by up to 10 carbons) than OTC. Monodomain ARO/CYCs have a single ARO/CYC domain, and are often associated with C9-C14 first ring cyclizations, these latter domains belong to a different subfamily in the SRPBCC superfamily.	3.9169e-45
NZ_CP010849.1|WP_044378262.1|248733_250161_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.00425e-22
NZ_CP010849.1|WP_044378251.1|239299_240535_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.91451e-69

Protein sequences

>NZ_CP010849.1|WP_044378247.1|237255_237489_-|hypothetical-protein
MDGVGGRAAWLRIERGRATDEEVAAVAVTLLSLLARCAGGAEGAVDGAAGAGGGQDGAVLWERGERAGGYRAPGSWR
>NZ_CP010849.1|WP_044378245.1|235514_237107_-|acyl-CoA-carboxylase-subunit-beta
MATVLEPSAGLAGPSDARGRLAELEAARALALAGPGRKATQAQHGKGKLTVRERIGLLLDEGSFREVEQFRRHRASGFGLEGNRPYTDGVVTGWGTVEGRTVFVYAHDFRIFGGALGEAHAQKIHKIMDMALAAGAPLVSLNDGAGARIQEGVGALAGYGGIFRRNTRASGVIPQISVMLGPCAGGAAYSPALTDFVFMVRRSAQMFITGPDVVRTVTGEEITHNGLGGADVHAETSGVAHFVYDDEETCLAEVRYLLSMLPSNNRTAPPAVPSADPPGRRSPALLELVPAEGSRPYDMHEVIAELVDDGEFMEVHERWARNIVCALARLDGSVVGVVASQPQVLAGVLDIEASEKAARFVQMCDAFNIPIVTLLDVPGFLPGVGQEHGGIIRHGAKLLYAYCNATVPRISVILRKAYGGAYIVMDSQSIGADLSFAWPTNEIAVMGAEGAAGVIFRKQIAAAADPEAARARLVKEYKAELMHPYYAAERGLVDDVIDPAATREVLIASLAMLRSKHADLPSRKHGNPPQ
>NZ_CP010849.1|WP_044378243.1|234739_235420_-|TetR-family-transcriptional-regulator
MVQQERAERTRQSLMRAAAEAFAEDGFVSTTLSTISKRAGVSNGALHFHFANKHVLAQAVEAAAVDTLRRITRDAEQCQDSALQRLVDATHGLLGSLERDVVVRAGFELTGTAPRRDQAADLYREWQRWVRRVLHTAQQQGELADGVSPAQASAAVVAATVGFEVLGAKDPAWVSRRVLGQYWDLMLPRLAAPGRLPALAPHGSAPHRTDPPRHPHPANRSSCFGA
>NZ_CP010849.1|WP_044378241.1|233663_234485_-|AfsR/SARP-family-transcriptional-regulator
MDIDVLGALAVQENQVSITPTAPKPRQVLALLALHADRVVPVSALMEELWGTTPPRSARTTLQTYVLQLRELITTALKNDPAGRTAKDVLVTTPGGYLLCGGGGRSDVREFERLAGAGYRCMDAGDFPGAARQLSEALLLWSGTPFADVQAGTQLEMEIKRLDESRLCALDQRIEADLRLGRHREVLAELTVLVNRYRTHESLHAQFMLALHRSGRRGEALSVYQGLRSTLVRELGLEPSAALRRLQRSILMAGPESMATAPDSVTERLAPTS
>NZ_CP010849.1|WP_044378238.1|231717_232539_-|AfsR/SARP-family-transcriptional-regulator
MKIQVLGPLSAEVNGGSIVPTAGKPRQILSLLALYPGRVMPVPMLMEEIWGTEPPPSALTTLQTYILQLRRRLGTAMGPDAPGAAKEVLATRHGGYLMQIPAESVDVHEYERMITEGRSAFESGDDNGSADCFRRALSLWRGPALVDVRVGPILEIEVMRLEESRLGTVERRIDADLRLGRHSELIAELTELTARYPQHEGLHSQAMVALYRSGRQASALDIYRRLRIRLIEELGVEPSPQVQRLHQAMLAVDPQLDVAAGPRRSSTFDLYAA
>NZ_CP010849.1|WP_044387236.1|230199_231156_-|cyclase
MPGERVRRLSHAVDVAAPAGVVYGLIADAERWPLYFPPNVYVERLDFDGVRERLRMWCLADGQVKSWTSGRVQDSARRRISFHQDQIMEPAESMGGVWSVQPLGPDRCRLTVEHEFTAVGDRPEDVAWLEQATIANAHSDLRSLRFLAERWARLDELVLSFEESVRVKGPAELVYGFLYDVADWPGQVPHVRRVDLAEPQVGVQKVTMGLAAADGGTHTVESVRVCFPHAGRIVHKDTATRKLVAAHCGEWSLVPDERGVTVVSQHHVVLREKDIARTLGAGATLEDARHHVRAQLGYESLQTLRLARQHAESAVRVL
>NZ_CP010849.1|WP_107071132.1|228134_229436_-|hypothetical-protein
MTVERNVDVSLTAVLALNGTAPGAPSTLELRGPLRTALLEAALARIAADRPELRDIRPRTLRSEPGHHVLELDAPYPSGVLADLLTAATAEPAGRPGAVTPRAPAPRPPAPALPEALALTPLQRELLARTAHRPHQQVAQLAWRWHGPLDTGRFTAAWQSVFDHETVLRAAFAFDPQPQAALHARAHPEVVRHAHGTLTRQALMDQERGRGFDLARPGLLRAALLDGEPQQHPAGHIPPTDVVLTYHRALLDSFSVRLLLQEFHRAYLAAGLAHGGERRPDLRDYRRWLATQDAAPARDFFARTGGDLGAGLPRARPAAVTGRHGPGRTLARLTPAEATRLAHWAARWGPTESSALQAVCRITSYNVCYTKLLRAPAATSAPACPAPAPAPSPAGTAPAAPWPASPTPKPPAWPTGPPAGARPRAAHCRPSGR
>NZ_CP010849.1|WP_078968997.1|227124_228336_-|hypothetical-protein
MLYEVITRTGGDLGAGLPRARPGAVTGRHGTGRTLARLTHAEATRLAHWAARWGATESSALQAVWAMILLRAGGTARGPAPVSFSVTVSGRGIPMEGIARVPGPFDNPLPVSLDIDPAATVPALLRTVRDRVLDLGAYEWVTAGQIKQWLGYDADADAPHTLLSFEHRPRPAKDLAADLAAQGIHVEDADPAGLQTTFPISVLAHRDGMGGLVLTSLHDRGRLHDDQVARMLDHSARLLRRLPARAEETTTVAQMLSELDDTAAPRLYDHPPASAERRLTRLRGPSRPGAKTVCLIAPPGTPEGCHRELARRYQGPEALTALRADAAGLPESLTALRPLLAAGEHLILGGFSGSGALACELARHIAADTGTAPLVVLGAGHDAGEDRVRDLARALGAAARRPG
>NZ_CP010849.1|WP_044378236.1|225831_226941_+|AfsR/SARP-family-transcriptional-regulator
MQFRILGPVEIQDERTGLRILPTGAKQRALLGALVVKAGREVSVHRLIDELWGDDPPANAANALQAHVARLRRRLPGPHAPHAPDGPDGREGAGRWGGAGSPGSPGGAGGAGGPGGLPREWIATRSLGYVLHLGPAGTDAQRFHALAAQGRQAAAHDPARAVELLRESLSLWRGPALEGSTHGDICAAEAAQLEEHRITALETMYDASLRAGRHGEVTGELEELTTDHPMRERFHDLLMVALYRCGRQAEALNIYDRVRRRLVRELGVEPGPALRGRMEAILRQDPVLALSGPPARARLRPLPDSPGQDHGQGQGQGQGQGEAEATVLSLGSEIASLHHRIEGLRLQQEQLVRRFEQLTATAGDRVAGL
>NZ_CP010849.1|WP_044378234.1|224983_225730_+|thioesterase
MDGTPPALRLFVFHHAGGSHVTYRHWPGLLPERWDVRLLDAPGRGRLGDLPQLDDAGRLADFFLRRLEDELQQGPCAFFGHSMGALVAYEMTVRLAAKGGRLPVWLGLSARGAPLARGEERQHHHLPDAELQTHLELLGGTPDEVFDNPDLWALYGPLIRGDMRLVETWRPRPGTPALPVAMSVFGGREDRSVPPERLAGWARHTERFLGLRVLDGDHFYFQDDPGPLLEWVCRDVAAALDSTAAVSW
>NZ_CP010849.1|WP_044378249.1|238536_238827_-|hypothetical-protein
MRPWSTSAVRDLRCLLNEWDPVGVADAVPDEYDCMLAPLLGRLHGGAGQEEIAAFLRYELEDHFGLDALGVRCDAVAARVTAWWACAGPGGGAADA
>NZ_CP010849.1|WP_044378251.1|239299_240535_-|cytochrome-P450
MEAVACPYALDVLGRDLAGEAAVLREGGPAVRVELPGGVMAWAVVRPGYVRRLLRDRRVSKDARQHWPAFVEGRITQEWPLFPWVAVENMLFTYGERHARLRRLVAGAFTVRRTQALRPGVERNVAGLLGSLAGVPAGQVVDLRAVFCERLPMQVICDLFGVEEEPGRRLCEAMQTVFSTSVSAQEMTAAQARVFGMLAELVAAKQEVPGDDLTSALIAVRDRGEGLSGQELLGTLNLMIAAGQETTSTLLTNAVAALLAHPEQLGHVRAGRAGWEDVIAETMRTRAAAAYSPMRFAVEDIELDGVLIEKGDPILVSFAAAGLDPEQHGEDAAVFDVLRADRRDGLGFGHGVHFCLGAPLARMEAGVALAALFERFPGMALARPVEEIDPVPSFIINGYSSLPVVLQPSAA
>NZ_CP010849.1|WP_044378253.1|241534_242236_-|TetR/AcrR-family-transcriptional-regulator
MARQERATRTRQAILVAAGEVFDEVGYEAATIAEILKRSGVTKGALYFHFPSKAELAQSVLAEQVHALPVVPRRELCLQRSLDEALLLAYLLQRDTGDAIVRGSVRLTVDQGAPRDELDRRMPMQAWEGHTLQVLEEAKAAGEVLAHVDLVRVTKVLVGGMTGVQVLSNIMTGREDMPERVADLYRHVLPAVAVPAVLAQMDFAPERAGRVYEEAVGAQDGARSGGLAPAVTG
>NZ_CP010849.1|WP_044378256.1|243589_245593_+|acyl-CoA-oxidase
MIATTFEAGPVATGTPRAGELSRLLFDTDGPDHSHDTWRALVSRDEFRYNPHLTRTERIAQSYRRLRLVNDTLDNPQDLARNPGRLAALHEWIGFTDGGLCTVASIHYNLFLGSLLDHPHPTRDLTPYTTLENTGTFLCTELDHGNDAAALETTAHYNPTTNDFTLHTPTPGARKFMPNTSLTGGPKTALVAARLITGTKDHGVYLFLTPLHTHNQPHPGITIQPLPPTNGPTVDHCLTAFDHVRLPREALLEGVHGRLAPDGTLTSFLGNRRKRFLRSIGRVTAGKLCMSAGTLGITRAALTIAVRYAHSRLVSASRAGERVPLAAHRSHHGRLLEGLATAYAMTFLHRTVVDRWAGRTEEDQADAERLTAVAKGWITWQARAITTECRERCGAQGLFPVNGLADLASNIEGGITAEGDNLVIWLKAASEMLFGHDTTARTRAGATGVPNSSPALSALDGPAAPATPSAPGGTVTPGAPGAPGAPGAPGAPGAPGAPGAPGATLTDPRFLHDLLADAEGIWRERARADLRDGPSGDPLGRWNGASSAAVEMVSAHAVLQAAGTLIAAAGHADGPTARQLLRSLSRLFLLRHLAPHTGDLLAEGRMTADHVRALPGSVDSVYEGLAPHLMTLVEAFDLPGEMLSAIPIANAAHETRFDQIVDTLLSA
>NZ_CP010849.1|WP_044378258.1|245637_246261_-|DUF998-domain-containing-protein
MQLVPRWVLLSSGSAPVLLIAGWSIAAALRGPDYDPVTQTISVLAAYGTPGFWVMTGALLALGVCHLLTAWGLRAAATAGRVALGAGGVSAWAVVLLPAPSSGGSLRHGTVAVVGFVLLAVWPVLAVDGVGTAPWCLRPVPCVVVTVFMGVGGAWFLVEMHRQGVVGVAERVVTAVQSVWPFVVAASCSRGSRERGRQAVGQEAGGG
>NZ_CP010849.1|WP_044378259.1|246448_247411_+|hypothetical-protein
MNHSFDRRTLLRAGGGVGLAALGLGYGAGAASAAVPTSKRFELSSVDSHDLYRNRALQDGTVQQSFAFDQTNRRLFVAQLRQGSDSKSGDLCITELEWSTWNAIGHMYLTGFGHAVSIGAQAVGTSTYLWTDVDADTSGYGKRLARFKYVNGTTLAASSSAVTKRTPVSTAVRHTCAIDPTHDRLIVRYLPSGSSVHRYAAYDLTAATNGDFTTRLVDFVEPSAIEAANFQGYTAYGQYLYCLSGHSNTDDATLWSVDMNTGGVTERFVTGAGSTLSFREPEGMAVYTTAAGEPRLFFGFASGDTTNQRLSNVFYKNVLV
>NZ_CP010849.1|WP_044378261.1|247582_248590_-|Lrp/AsnC-family-transcriptional-regulator
MESVTVSETDLQLLHALQISPRLPWNVLGDVLGISPTTAARHWARLSGEGLAWVTAYRPDLAGQLGDPVNALITAVCAPGRLSTIAQTLATHPQMLSVEIVSGDGDLHLTVAAPDRQALADYLLGPFAAVDGLLQSSTCWVTRLHKEGSKWRLRALSPAQVRRLRELTEPARAVVSPVPRRPLDAADERILAALSTDGRASYAALAEAAAVSEPTLRRRLRRLMDTGRVAVRCDVAWEAAGWPVQTILALRVPVDRLEETARALTARSETRLVATCVGESDLVVTAWLPSLADAHPFATMLAERFPGVRVVRWLTGLRAVKRMGQPLDERGRALR
>NZ_CP010849.1|WP_044378262.1|248733_250161_+|MFS-transporter
MTVSPPPPKAAAGQSAAPARIGAVVGFMAFVELTSGIFQGFVPPLLPSIATLHHVSAGDIALVTSLQLLAAAVCVPVLTKLGDMYGHRRMLRLALGVVVLGSLLVAWAPSYEVLLVGRLLTGPLSAWLPLEIAITRDKVQGETGRRAIGLLVGCLTGGVALGSLLAGPVEDLLGGVRPALLVLTVLAALALGCAVFLIPETSTRAARRIDAAGFVGLAVALLLLQYGLSQTSKLGWGSSAVLGCLLGGIAVLAVWTWWELRIEQPAVDLRVIGNRSMWPVQLAAMLFAIALFGSQSPNSTFLATDPDETSYGFGLDTTGIALITLPSQIVSVIGASLHSRLAARIGLHRTIATGAALLAVGYGALCVAHSHPASFALTTTLVGCGVGLMSGGFPSLVAERAPAGQTGIAAGIYNTLRTLAGGIAGGLFAVVLSNVLLAGSSLPSAEAYRVVWLTCAVSGLLAAWLVLFARRRTTA
>NZ_CP010849.1|WP_044378263.1|250326_251547_+|amidohydrolase
MPTEPTTPAPSFRERAEALAPGLTALRHALHREPEIGLELPLTQAKVLAALDGLPLEITTGKSLSSVVAVLHGGRPGPAVLLRGDMDALPLQELADVPYRSRFDGVMHACGHDQHVAMLVGAARLLCERGEELPGSVVFMFQPGEESYDGARHMVEEGLLEAAGKPLVGAYSVHVSSNGPECGTFHGRVGTQTAGNAELKVVVRGKGGHGSTPHTAADPVPVAAEMVLALQNLVTRTTSVFDPVMLTVGLFQAGTKLNIIPGTAEFEATVRATSPAAMADFLPRAVRLVEGIAEGWGMTAEIDAHEVYPAMIAAEEAVALGRRVVGDLYGQAAWFTAEHPIMASEDFSRVTAVVPGVQLGLSARPADVDEATAPFNHSPYSVFDDAALPRGAAVLAEMAARRLAAG
>NZ_CP010849.1|WP_044378264.1|251897_252176_+|hypothetical-protein
MSLRRSLASALGVVLLGLGLPLATPSGAAADPCGFYKTGSDAFYNHCTSDGSNVVIEVEVRGPNYERCVGPGRSWLGSSGRINGAFYTGRTC

Crispr_ID: NZ_CP010849_2

• CRISPR_ID: NZ_CP010849_2
• CRISPR_location: 762093-762342
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP010849_2

Consensus_repeat	Method
GGCGGACGCCGGGGATTCGGCGGGCGCC	CRISPRCasFinder

spacers of NZ_CP010849_2

>2.1|762121|41|NZ_CP010849|CRISPRCasFinder
GCGGGCGCGCCGGGACGAGCGGGCTCCGCGACGGCCGGAGC
>2.2|762190|29|NZ_CP010849|CRISPRCasFinder
GTCGGGGCGGACCCGGCGGGTTCCACGGC
>2.3|762247|23|NZ_CP010849|CRISPRCasFinder
ACGGCGGCCGGTGCGGCGGAGGT
>2.4|762298|17|NZ_CP010849|CRISPRCasFinder
GGGGATTCGGCGGGCGC

CRISPR arrays and Neighbor proteins around NZ_CP010849_2

CRISPR arrays

The CRISPR arrays of NZ_CP010849_2

>merge|NZ_CP010849|2|762093-762342|CRISPRCasFinder
ACGCGCCGCCGGGGGCACGGCGGGCGCGGCGGGCGCGCCGGGACGAGCGGGCTCCGCGACGGCCGGAGCGGCGGACGGAGCGGACCCGGCGGATGAGGTCGGGGCGGACCCGGCGGGTTCCACGGCGGCGGTCACGACGGAGGCGGCGGGCGCCACGGCGGCCGGTGCGGCGGAGGTGACGGGGGCCGCGGTCGCGGCGGACGCCGGGGATTCGGCGGGCGCCCCGGACGCCGGGGACCCGGTGGGCTCC

>NZ_CP010849|2|2|762093-762342|CRISPRCasFinder
ACGCGCCGCCGGGGGCACGGCGGGCGCG	GCGGGCGCGCCGGGACGAGCGGGCTCCGCGACGGCCGGAGC
GGCGGACGGAGCGGACCCGGCGGATGAG	GTCGGGGCGGACCCGGCGGGTTCCACGGC
GGCGGTCACGACGGAGGCGGCGGGCGCC	ACGGCGGCCGGTGCGGCGGAGGT
GACGGGGGCCGCGGTCGCGGCGGACGCC	GGGGATTCGGCGGGCGC
CCCGGACGCCGGGGACCCGGTGGGCTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_078969035.1|740066_741374_-|peptidoglycan-recognition-protein	unknown	unknown	gnl|CDD|128941
NZ_CP010849.1|WP_044378971.1|798259_799021_+|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|187629
NZ_CP010849.1|WP_078969036.1|788806_797416_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|238429
NZ_CP010849.1|WP_044378968.1|779582_788792_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NZ_CP010849.1|WP_044387367.1|800732_801281_+|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl|CDD|237597
NZ_CP010849.1|WP_044378949.1|738385_738793_+|four-helix-bundle-copper-binding-protein	unknown	unknown	gnl|CDD|153434
NZ_CP010849.1|WP_044378947.1|736759_738184_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP010849.1|WP_044378951.1|738893_739769_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238861
NZ_CP010849.1|WP_044378943.1|734657_735017_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP010849.1|WP_044378966.1|771249_779541_-|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NZ_CP010849.1|WP_044378961.1|744742_745966_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP010849.1|WP_044378946.1|735148_736552_+|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl|CDD|379355
NZ_CP010849.1|WP_052808553.1|804829_806092_+|hypothetical-protein	unknown	unknown	gnl|CDD|225306
NZ_CP010849.1|WP_052808550.1|799297_800461_+|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_CP010849.1|WP_044387361.1|746073_749364_-|ACP-S-malonyltransferase	unknown	unknown	gnl|CDD|240093
NZ_CP010849.1|WP_044378973.1|803187_804510_-|acyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|214838
NZ_CP010849.1|WP_044378958.1|743396_744584_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP010849.1|WP_052808554.1|806088_807567_+|hypothetical-protein	unknown	unknown	gnl|CDD|238429
NZ_CP010849.1|WP_159392861.1|801713_802826_+|acyltransferase-family-protein	unknown	unknown	gnl|CDD|224748
NZ_CP010849.1|WP_044378954.1|741547_742867_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|224567

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP010849.1|WP_044378943.1|734657_735017_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2e-22	74.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_078969035.1|740066_741374_-|peptidoglycan-recognition-protein	gnl|CDD|128941	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.	9.60099e-42
NZ_CP010849.1|WP_044378971.1|798259_799021_+|3-hydroxyacyl-CoA-dehydrogenase	gnl|CDD|187629	cd05371, HSD10-like_SDR_c, 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs. HSD10, also known as amyloid-peptide-binding alcohol dehydrogenase (ABAD), was previously identified as a L-3-hydroxyacyl-CoA dehydrogenase, HADH2. In fatty acid metabolism, HADH2 catalyzes the third step of beta-oxidation, the conversion of a hydroxyl to a keto group in the NAD-dependent oxidation of L-3-hydroxyacyl CoA. In addition to alcohol dehydrogenase and HADH2 activites, HSD10 has steroid dehydrogenase activity. Although the mechanism is unclear, HSD10 is implicated in the formation of amyloid beta-petide in the brain (which is linked to the development of Alzheimer's disease). Although HSD10 is normally concentrated in the mitochondria, in the presence of amyloid beta-peptide it translocates into the plasma membrane, where it's action may generate cytotoxic aldehydes and may lower estrogen levels through its use of 17-beta-estradiol as a substrate. HSD10 is a member of the SRD family, but differs from other SDRs by the presence of two insertions of unknown function. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	6.16183e-128
NZ_CP010849.1|WP_078969036.1|788806_797416_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	0
NZ_CP010849.1|WP_044378968.1|779582_788792_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP010849.1|WP_044387367.1|800732_801281_+|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl|CDD|237597	PRK14054, PRK14054, peptide-methionine (S)-S-oxide reductase.	1.05873e-48
NZ_CP010849.1|WP_044378949.1|738385_738793_+|four-helix-bundle-copper-binding-protein	gnl|CDD|153434	cd08026, DUF326, Cysteine-rich 4 helical bundle widely conserved in bacteria. This functionally uncharacterized protein forms a 4-helical bundle with a bromodomain-like topology. It is present in major bacterial lineages and contains highly conserved cysteines in a repeated pattern, whose sidechains appear buried. Some family members have been (mis)annotated as putative ferredoxins.	6.44914e-22
NZ_CP010849.1|WP_044378947.1|736759_738184_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	9.68514e-21
NZ_CP010849.1|WP_044378951.1|738893_739769_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	9.12879e-64
NZ_CP010849.1|WP_044378943.1|734657_735017_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.67085e-21
NZ_CP010849.1|WP_044378966.1|771249_779541_-|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP010849.1|WP_044378961.1|744742_745966_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	6.6652e-89
NZ_CP010849.1|WP_044378946.1|735148_736552_+|NAD(P)-binding-domain-containing-protein	gnl|CDD|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	5.34397e-20
NZ_CP010849.1|WP_052808553.1|804829_806092_+|hypothetical-protein	gnl|CDD|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.94782e-19
NZ_CP010849.1|WP_052808550.1|799297_800461_+|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	2.26464e-27
NZ_CP010849.1|WP_044387361.1|746073_749364_-|ACP-S-malonyltransferase	gnl|CDD|240093	cd04742, NPD_FabD, 2-Nitropropane dioxygenase (NPD)-like domain, associated with the (acyl-carrier-protein) S-malonyltransferase FabD. NPD is part of the nitroalkaneoxidizing enzyme family, that catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDPs are members of the NAD(P)H-dependent flavin oxidoreductase family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN.	8.70657e-145
NZ_CP010849.1|WP_044378973.1|803187_804510_-|acyltransferase-domain-containing-protein	gnl|CDD|214838	smart00827, PKS_AT, Acyl transferase domain in polyketide synthase (PKS) enzymes.	1.72309e-121
NZ_CP010849.1|WP_044378958.1|743396_744584_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	9.11092e-76
NZ_CP010849.1|WP_052808554.1|806088_807567_+|hypothetical-protein	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	0
NZ_CP010849.1|WP_159392861.1|801713_802826_+|acyltransferase-family-protein	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	6.96195e-25
NZ_CP010849.1|WP_044378954.1|741547_742867_-|extracellular-solute-binding-protein	gnl|CDD|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	4.57927e-22

Protein sequences

>NZ_CP010849.1|WP_044387361.1|746073_749364_-|ACP-S-malonyltransferase
MFSGQGSQYYHMGRELFDRNEVFRTTLRGYDAVVAEELGESVLARIYDPARSKADLLIDTRITHPGIVMFELALARTLRELGVEPDYLLGSSLGEYAAAVVAGSLDAADCLRLLVRQAEALRGSPPGGMLAVLAGPRVLDRVPALRACEIAARNAPGHFVVAGTREALARAEAELRAADVLHQRVPVEYGFHSRLVDGVLEAGRATFEGVPLAPPRIPWVSCVDGGLVERPTPEHFRRVAREPIEFERTMARMRDRGDFRYLDLGPSGTLHAFVRNNLPAGTGSESLPLLSPFGNDTDLLEQTRIRAANTPRKAHGMKVYGFPGQGAQRRRMGAGLFEKYPEQTALADRVLGYSIEELCLADPERRLGRTEFTQAALYVVGALSYLDHTERDLVPPDYLVGHSLGEYAALFAAGVFDFETGLRLVQRRGQLMAAADGGAMAAVVGVDEAAVTRMLADPTFHGLDLANHNALDQFVLSGPGEQLDAACAAFDAAGARTVRLHVSAPLHSRYMRGAAEEFARFLDGFTLRPPRIPVLANVDALPYTAESLKERLAAQIASPVRWTETVRRLMGHGDFTFVELGPGQVLTKLVARIRAAAEPIPPTAPAPAAAPASPATSPAPATVPAPPATVPAPPATVPAAPATVPAAPATVPAAPATVAAPPAAGIPEGRRERAIDAESLGARTFRERYGLRRAYLLGSLYGGVSGPDMLRSAAKAGLLGFLGAGGLTVDETERHLRALTDDLGLGGSFGVNVLYRHGAPEQEAALVDLLLRRGVDLIEASGFPMMTEGLVRFRLKGGRILAKVSRTDVAAEFLAPPPTALVERLLAAGAVTEAEARAAAGRPMADDLCVEAAGGWLHTTADALTLLPAVLRLRDETALPGRRVHVGCAGGIGTPEAAAAAFLLGADFVMTGSVNQCSVEAATSDAVKDLLQEAGEYDIDTAPWGEMFELGVQARYLKRGLFFPARASRLHELWRRHPSLDAFDDDTRAQVLDRYLGGEPPLPVPPDAGPRAELAALLRRYFERGFRLAVTGDERSRVDYLIHCGPAMGAFNQAVATSDLRDWRARTVAAVADTLMDGAAAHITGRLRSLHETRTE
>NZ_CP010849.1|WP_044378961.1|744742_745966_-|cytochrome-P450
MTTETPSEPLIFNPFTPDFMSDPYPHYAELRRHVPVHEHPGGFWMLSRYEDVSALMRSGLSVEQRHVAPGPFRDAYARAGVTDEPRLKGLALLDRDAPDHTRLRKLVTMAFTARAVNAMEGEIRSLVDEALDRIAADGGGDLVEALAFPLPFTVISRMLGMPPTDTVRMRTLTHTLMRSVEPTTDPEVMRAVEAADAELFDIVGEAVDWKRQNPADDLLTALITAEDHGDVLSRDELIAQVTMLYVAGHETTVNLISGGTLALLRNPGQLRLLRDKPELEQNAIEELLRYDAPVHNSRRITLEPYEVGGHEIPPGSFILANLAGANRDESYFGPDAEELRLDRENARRHVSFGGGMHLCLGAALARIEGRVAIGGLVRRFPGLELAGEVEWNGLLSLRGAARLPIRV
>NZ_CP010849.1|WP_044378958.1|743396_744584_-|cytochrome-P450
MTSVDHSTASTVADLPVAERRDDAWRTLSDRGEVVPLADGLAVTSLAVVKAVLREPGRFSIQKVFEAVETGYPLIPLAFDPPEQTRYRRILQPFFSPRRIRPLEESLRAQAVALVEAVKARGACDFVADIAGPFPAQALLTLLGLPLEDRDRFIGWKDAALRLTADAAGEVPLTDEERAAEVAQTMAMGGYLAELIRTRREEPGDDVLSEILALRGEDRLSDDEALGVCLMLVLAGLETVTDALGLGMERLATHPERQQELVRDLSLVPAAVEELLRLDPPAPFLPRMTTEDVEIAGCPVPAGTLINAHLNTANRDEACWPRAHEIDFHRAENPHTSFGLGVHRCLGTHLARLEMRLVFEEWHRRIPHYAITEGTSHRARLVRANLGLESLHLTF
>NZ_CP010849.1|WP_044378954.1|741547_742867_-|extracellular-solute-binding-protein
MGKRKALTGALLATAILTVAGCSGTGTASGETAKAPADPADATGTIKVLTSRTDLVQDGTMDEYAAEFNKTYPKVKVEFEALTDYEGEVKIRMNTDDYGDVLMIPGVVTKNDYPKFFAPLGTAEEMRAKYRFSDSTEVGGKVYGIAQFGAANGFVYNKAVWKKAGITEWPASPEEFLDDLRTIEARTDSLPYYTNFKDAWPLTGWTNNVGSAGCDAEANNKLAGAVSPWKQGGDLRMIDTLLYDIVKNGLSEKDPSTTNWEASKGMIAKGEIATMQLGSWAVKQMREAAEKAGTDPEEIGYMPFPVQKDGTFCTMVASDYQQAVNIHSEHKAAARAWIDWFTHESGYSANEGAVPAVKTSPMPRTLKDLVDNDVSFVERSDAKAAQVNAIDNAAEIGLNKPDYRRQLIDLARGARKGSLEDFFADLDKRWNEAAATAGS
>NZ_CP010849.1|WP_078969035.1|740066_741374_-|peptidoglycan-recognition-protein
MIRPTPGGCHTRVRSCSAGRRGSRHVWSRARWAAGAAAGTLVLDIFWGAGAHGYGGQGAGAPLKGLDRSRTAPIPAVRDGAVLSGTDTRPFRLLGVTWDDPDAHLAATVEVRTRAMGTARWSGWLKLDGDDAHGEETALRGGTAPVWVGPSDGVEVRVGPAPDGSFTLPAGLRLDLVDPGPGGPAGSAGPAPLAEPVTASQAAAAPRPAIVSRAGWGADESLSPEAPAYLPDGKVKAVVVHHTAGSNTYTCAEAPAVLRGIHAYHVQQLGWKDIGYNFLVDKCGTLYEGRKGGVDRAVLAAHAYGFNTETSGIAVLGDYTDVTPAGAVLDSVAKLAAWKLGQYGVSPTGTTTLTAGAAGRNHAGATWAKGAKLSFPTIHGHRDGYNTECPGERLYAELPTIRTRAAAFAAGTSAESSRGGAVPAAEGNVLTAPRT
>NZ_CP010849.1|WP_044378951.1|738893_739769_-|SGNH/GDSL-hydrolase-family-protein
MPRRALRRALAAMATAVSAVAVGLAAPTAHAAEPLTYVALGDSYSAGSGILPTDPRAPLLCLRSALNYPNVIAGRTGAALTDVTCGGAQTKDFSAAQYPGVPPQLDAVGSGTRLVTLTIGGNDNNTFIGALLACGTAGIATGGQGSPCETLYGSTFEDRIEGNTYPAVKAALQRIRAKAPAAQVAVLGYPWILPPTADPSCYAKMPIASGDVPYVRGIQARLNAVIARAARETGTTYVDFSRTSEGHDACRAAGTRWVEPLLFGTNVVPVHPNALGERRMAEQTLTALGLG
>NZ_CP010849.1|WP_044378949.1|738385_738793_+|four-helix-bundle-copper-binding-protein
MTTVKDMLATYPADLGGIDRDRLARCVEECIACAQACTACADACLSEGMVGQLTKCIRTDMDCADICEATAAVLSRHTGYDANVTRAILTACATACKACADECSTHADMHEHCRLCAEACRSCEQACNELVQALG
>NZ_CP010849.1|WP_044378947.1|736759_738184_+|Gfo/Idh/MocA-family-oxidoreductase
MSETPAVSRRLLLGGAVATGALAAGIAGSAQTASAATEQAPRRRPGQKSMIGVPFDAHRTVRVGVIGLGNRGAGMITGWAAVPGCTVTAVCDIRADRAKRAADRLVSRGEPRPAEFGGSADAYTEMLKRDDIDLVYIATPWEFHHEQGRAALLSGRHAMVELPVATELRELWDLVDTSERTRRHLMLAENCCYGRNELAVLKMAHDGLFGDITNGHGGYLHDLRELLFSDTYYTDSWRRLWHTRSTASLYPMHGLAPIAGAMDINRGDRMTTLRATSTAAKGLADYRERFVPRGHPSWKETYINGDLVTCLIETEKGRTIRAEHDVSSPRPYSRINSLAGSRGIVEDYAGPAPTGARVYLEPDHGGHTWRDFAGYRTEFDHWLWRTVGDDAANNGGHGGMDYVMQWRTVQLMRLGLAPDIDVYDSAAWCAPVPLSAASLARDGRPVEIPDFTRGGWAGARAGLDSRAVEMPPAS
>NZ_CP010849.1|WP_044378946.1|735148_736552_+|NAD(P)-binding-domain-containing-protein
MTASAFSDLPVAVIGAGPIGLAAAAHLAGRGLDPLVLEAGPAAGAAVREWGHVRLFSPWSEVVDPAAEKLLAPTGWTRPDGASYPTGGEWAERYLRPLAAVLDDRVRFRTTVTGVSRAGRDRIVDAGREDQPFVLHVRYEDGREGRVAARAVIDASGTWSGPGPAGGNGLPALGERAAADRVAYRVPDLADPAARARYAGRRTAVIGSGASAFTALAALAELARARDGAGTRAVWILRRGLSATTFGGGSADQLPARGALGLAAKAAVEDGHADAVTGFRTEAIERDGSGRLVLVGDDGRRLDAVDEVIALTGFRPDLSFLSEIRLRLDERLQAPAALAPLIDPNVHSCGTVHPHGHAELSHPEPGIYLAGMKSYGRAPTFLAMTGYEQVRSVASALAGDTDAADRVELTLPETGVCGGSGLYDSPEPGRTGADGCCAAPAPQTLPLISGSTGSTGSGETSGGCCGG
>NZ_CP010849.1|WP_044378943.1|734657_735017_-|winged-helix-turn-helix-transcriptional-regulator
MSKPEEKWTVPPAQPCCPALTERELTAEEAEATAAMFKALGDPVRLRLFSKVASHPDREACVCDIADVGVSQPTVSHHLKKLKEAGLLVSERRGTWVYYRVEPSVLAAMGRLLTVPAAA
>NZ_CP010849.1|WP_044378966.1|771249_779541_-|type-I-polyketide-synthase
MATSRPGERAIAVVGMSCRVPGADGIDAFWRLLRVGVDAITEVPAGRWDPDGVPDGPEPPGLRRGGFLDGVADFDPAFFGISPREAEAMDPRQRLALELSWTALEHARILPRTLRGGGAAVFLGATGDDYAALVHRHGGDAVSHHSMAGLSRGVIANRVSYHLGLRGPSLTVDAAQSSSLVAVHLACEALLSGATGLALAGGVHLNLTPDGTLAFARAGALSPDGRCHTFDARANGTVRGEGGGMVVLKRLADAVADGDPVHCLLLGSAVNNDGGGQGLTVPDEDAQRELLRDAYARAGTEPARVGYVELHGTGTRAGDPVEAAALGAVLGADRPAGQPLLVGSVKTNIGHLDGAAGVVGLIKVALSLKHGAVPASLNFAEPHPAIPMERLRLRVNDTTGPWPQGPRLAGVSSFGVGGTNCHVVVADAPAAGAEDRAGAPSAAPVPVPVVVSGRTEAALRAQARRLRERVASDAGLSPADVGYSTVTTRTAMEHRGVVVAADRDELLAGLAALAAGEPSPHVVEAVAGSVSGVVWAFPGQGPQWAGMALELWDTSPVFAARMDECARLLDGMVDWSLREVLGDEDALKRMDVMQPALFAVQVSLAEVWRSVGLAPSAVVGHSQGEITAACAAGSVPLADALRLMAERSRVITARLSGRGAMALLALPAEEADFDGVTIGAVNGPRSVVVSGPVEAVHEAVAACKARGVRAWTVPIDYASHSAQVEEIRDEVLRAAADVPARDAGVAFYSTVTGGRLDADRLDAGYWYRNLRERVRLEETVRALAADGHQVFVEASPHPVLTLAIQDTLDDARTPAVVQGTLRRDEGGLRRLLLSMAELHAQGVTLDWRPMFEGTGARTVDLPPYAFQRSPYWLTPTAAATTAPAAPATETEARPEPAAPAAEGRATAGEADLMTLVRAQAAAVLGHPDADTVDTDRSFKELGFDSVTAVELGKRLSRATGLRLPATLVFDHPTPTALAGHLRAELAGPALPDGSPAAAGRTAAADDDPIAIVGMGCRLPGGVSSPEELWRLVAGGVDAVSPFPEDRGWDPDPAVTGHVRAGGFLTDPFGFDADFFRINPREARAMDPQQRLLLEVSWEALERAGADPALLRGSRTAVFMGVMDQDYVPRLHETTDSFGGYALTGGATSVASGRIAYALGFTGPAVTVDTACSSSLVSLHLAAQSLRAGECSLALAGGATVMSTPGMFAEFARQNGLSPDGRCKAFSDTADGTGWAEGVGVVVLERLSDARRNGHPVLAVVRGSAINQDGASNGLSAPNGPSQQRVIRDALARAGLSPADVDAVEAHGTGTALGDPIEAQALLATYGRDRTEPLWLGSLKSNVGHTQAAAGISGVIKMVLAMRHGELPRTLHAHEPSRHVDWSSGAVELLTERRPWPRADGPRRAGVSSFGISGTNAHVILEDPGPGPDGAPGGAPAGDRPALAGPVPVVLSGQSEAALRAQARRLRERIESDPGLRPADVGWSQAASRTAFERRAAVLAADREELMAALAALARGERARGTVQGTAERARGRVVFVFPGQGSQWAGMAVELLDSSPVFADSLRACGAALAAFVDWDLEGVLRQVPGEPTLERVDVVQPASWAVMVSLAALWRSCGVEPAAVVGHSQGEIAAACVSGALSLEDAARVVALRSQAIAKGLAGLGGMMSLALPLAEAETRLAPWQGRLEVAALNGPSVTVVAGDAQALEELRAACEAEDVRARRIPVDYASHTSHVERIEEDLAELLAELRPAPARVPFYSTVERDWLGDRLVDAAYWYRNLRRTVHFQSAVEALAEQGHDTFIEVSPHPVLTIGIQEILESRTGEAAEVITGTLRRHEGGPDRFLISLAGAWTRGVAVDWAGAFAGSGASLVELPTYAFQHRHHRVDAAADQPLLGRALDLADGDGTVLTERLSLRTRPWFADHRVLGQAVVPGTALLEMAFRVGGAVGELTLHTPLVVPDHGEVEVQLTAAAPDGDGRRAFRIHGRTPGGADTGWRLHATGVAGPAEPGDAVAALAEWPPPGAAPVDLTDAYDELARRGLEYGPRFRNLRGVWRHGEDLLADVALPDGAGPFSVHPALLDAVLHPLVLEYGPGPVVPFSWADVRLARAGAAQLRVRVSPAGEHRASLTVMDGSGAEVMTVGSLSLRPLDARRFDPRLFQVAWREAAATGPAEPAPSAVVLPVAPATAPLPEAVRTTAESVLREVQRHLARHTEHTEPTGDAGDAGDAGGPARLVVVTRRGAAVTPDASVDLAAATVGGLLRSAQTEHPGRIVLLDTDGDDEPTAEEVNRALATGEPQIALRAGRMLVPRLERGSVPAPRPDREGTAPDGTTLITGGTGGLGAAAARHLVARHGVRDLLLVSRSGPAARGARELVAELTAQGARVSVAACDVADRSALAEVVASVPASAPLRCVVHAAGVLDDAALLSQTPRHLRAVLSAKADAAWHLHELTRGLDLTAFVLFSSVSATLGLAGQANYAAGNAFLDALAHHRHRLGLPALSLGWGLWEETTGLTGRLGDADRQRMLRMGLRPLPTDAGLALLDLALEADRPHLVPAWLDPAGPGGAGTPAVLRGLVRTPAAPGAGARDDSRPPRDRLPALSGPDGALAMRRLVQTEVATVLGRSGPGDVPPDRGFGDLGFDSLTALELRNRLGALLGTTLSATVIFDHPSPAKLARHLLERLAPDRPAAPPPPPVLAELERLEASVADADDDLRSAVADRLWELLAAVSAPGGTAEAEPDEEVDTASADELYALIDDELGGSDHE
>NZ_CP010849.1|WP_044378968.1|779582_788792_-|non-ribosomal-peptide-synthetase
MGTIPHDHERAALAHKVRSLSAKRRRALFALLRKEGVDLSALDVMAPPPRTADEPVPLSFTQQRLWFLAQLDGASAAYNIPAAVRLRGHLDRTALVRALEAVVQRHEALRTRFADHDGVPYQHVGDGRDIEVRLEELADPADLPVICAGEAATPFDLERGPLFRARLLRASDQEHVLLVTMHHGVSDGWSVGVLFGDLVALYEAYCAGRPSPLEPLPVQYPDYALWQRQWLADGVQERQLGYWKKQLTGVDPRLTLPADRERPAVKTYHGAREVFRCPADLLERLRTVGARYDATLYMTLLAAYTVVLHRCTQQTDIAVGTVVANRGRSEVEGLIGFFANTLVMRTDLSDDPAFCELLTQVRKTALEAYDHQDVPFEAVVDALQAERSLAHSPVFQTMFVLQEARTGREDRLGELEVLPVEFDVDTTKFDLTLDLRETPEGLAGTVEYNTDLYDRETIQRFVGHYTTLLASVAADPEERVSLLPLLPEAERRRVLVEWNERPAVVAGGGRCVHEWFEEVAAARPGAVAVECEGRSLSYGELNARANRLAGHLRGLGVGRDVLVAVCVPRSEHMVVALLAVLKAGGAYVPLDPAVPVERLDHVLRDSGPRVLLVDGGVPEGLDPAGVPVVDVRADAGVWADLPGEDLSGVVGSSSGDLAYVIYTSGSTGTPKGVMVEHRNVTRLFTATEGWFGFGADDVWTLFHSFAFDFSVWEIWGALLHGGRLVVVPQAVSRNPREFYELLCASGVTVLNQTPSAFRQLIAAQGEEGAAHRLRVVVFGGEALDVAALKPWMRRGVNRGTRLVNMYGITETTVHVTYRELSWGDLEGSASPIGVRIPDLRVYVLDGRGGPVPVGAVGELYVGGEGVARGYLNRAELSRERFLPDPFCGQEGARMYRSGDLVRQLPDGSLEYVGRNDDQVKIRGFRIELGEIESTLAQHDAVRSCVVVAREDRPGDKRLVAYLVPEDGHTAGDLRAELARHAGRTLPDYMVPSAFVTLDGLPLTANGKLDRRALPAPGIDAYAQRAYVAPSTATERALAAVWAELLGFDETRIGAEDNFFQMGGHSLLITVLVARLKERGFDVPVRSVFSSPTLARLAAEIDGGARGPAYEAPPNLIPAGCERITPAMLPLIDLDQDRIDAVVATVPGGAPNVQDVYPLASAQEGILFHHLLDPDSDPYLVSILLAADDETVCTRFTEALQALIDRHDVLRTAVLTKDLPEPVQVVHRTARLVVERTRLDRGRDAEEQARALLARPRRMKVDEAPLLRLLIAEAPDSERRYLLLSAHHLIEDASTLRLVLEELAVHMAGRTELLAPAPPYRDFVGQTLHQTATDDAETYFRAALGDVTESTTPFGLTNVRGDGHAYPHLRRALPAGLTGELRAQARRLGISPACLFHAAWACVAAAASGSDDVVFGTVLSGRLQGVPGVERMLGNFINTLPLRVRLAGKTVQELVREVDGALRGLIAREQSPLSLAQRCSGLEGDTPLFSSVINFRHFEPRHGQDAPSLEETGIHWLAETDAINYPLTVSLDDFGGELSLDLRVDDAVACEAVADYVETALTGIVTALAADDGATTPALGIAVLPEAERRRVLVEWNERPAVVAGGGRCVHEWFEEVAAARPGAVAVECEGRSLSYGELNARANRLAGHLRGLGVGRDVLVAVCVPRSEHMVVALLAVLKAGGAYVPLDPAVPVERLDHVLRDSGPRVLLVDGGVPEGLDPAGVPVVDVRADAGVWADLPGEDLSGVVGSSSGDLAYVIYTSGSTGTPKGVMVEHRNVTRLFTATEGWFGFGADDVWTLFHSFAFDFSVWEIWGALLHGGRLVVVPQAVSRNPREFYELLCASGVTVLNQTPSAFRQLIAAQGEEGAAHRLRVVVFGGEALDVAALKPWMRRGVNRGTRLVNMYGITETTVHVTYRELSWGDLEGSASPIGVRIPDLRVYVLDGRGGPVPVGAVGELYVGGEGVARGYLNRAELSRERFLPDPFCGQEGARMYRSGDLVRQLPDGSLEYVGRNDDQVKIRGFRIELGEIESTLAQHDAVAHGVVLARASGDSRALVAYVHPTPQWFDSAAREQNAHLLDQWQRVFEDQYAGSQGEDVPDDLNLTGWDSSYTGEPIPESDMREWIDGTVRHIEELRPRRLLEIGCGTGLLLFRYAPACASVHALDLSPSALADVRRGVAERGWTHVTLEQGDALSVADLPEGGFDTIVLNSVAQYFPNRVYLEEALTRMLPLLEDGGRVLIGDVRNLDLLPAHLGAVERSRAGARTTAGELAARVRRRRRQESELLLSPTYFTRLPELFPELGAVDLVVKRGVGDNEMLAYRYDVILTKKAATTAEPLPWLEAGTPKALRELLDAGTPDRFGVSGLRNPRVADDVRISDGLARWSPSHEVDPLPGNGRLTARDAQETRELEAVLRHAETLGYRVAATWSQDRPDALDLVLGKGDLPPVRARAPYRAAHLANFPRIGDLGPSMARTLKEHLSARLPDYMVPGVFVLLEELPVTPNGKVDKRALPAPDEDALAKEEYVAPRTGTERILCRVLAEMLGLGRVGVQDSFIALGGHSLLAVRLNLRVRQETGRELPLQLILTGATVAEMAAEIDKEPAGAEDVPLLPAVPTRDGEEAPLSLQQRDLWFLNHPQHLENSYDNAQLAYRLTGRLDRDAFARAVRALAERHPVLRTGYVRRDGTVTQRVHADCDLELHVPAPVTGDDALAQWLRQERTRPFAPEDRHMVRVHLVPVADDEHVFVLTRPWGVFDGWSLTIVLPELMALYRALLRGTEAELPPVPLRYADYARWQRQVIGEAELDRQRAYWRRRLDGLPARAALRTDRPRGPVQSYRGAKVGLDVPLPVLARLRELGQDSGGTLYMTLLSAFAVLVGGHCDDRELAIGTPVTNRPKAELEQLVGYFVNTVVIRLDVTAERGFTDLLAQTRQVTAEAHEHKDLPFADLVRELVPYPDPAHSPLFQVMFNLVPMPRLTADGGDGTGGTGDGLDIAPVDADPGPAKYDLNLTVRETDSGLLGHLEYSTDLFTGETATRMARAYERLLAEIAADPGADLARLRARTARTSTDETA
>NZ_CP010849.1|WP_078969036.1|788806_797416_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTDSSILAETFTETFTVTTDNPLLRGHVVHGRHLLPGVGYVDLVLQVLARHGAVTPEVELRNLTILAPLVAEPGERVLATVEGRPAPAGGQRIEVRSRRPQDATDVLHAVVTAHPCPPAPFPERLPLPLGTADRVTTLADIYTWLRGNQLVHSGLMKSEGVVHRRGDDWLVELELAPPYHDSADSFLFHPALFEAGLLGGSVGNHMLHGGGASEGLYLPLVFESFRATARLGTRCYVRVPAGSSRRDDELMRLSVEFYDADGGKVAEVGGLVAKRVRDVSLLDVRESHAAQAPPAAAPPTAPDRSGGPDAPDVAGTVRALVAEQLKVPVTAVEAERGFYELGLVSVDLVSLVPALEDRLGLSLSPTIMFEYPSVAALTAWLEERVAERRETGPAGAVPPRPPAPPSPTDAPAPRSEAAPSTTTAPDVLGALLDETAALLKVPAAEIDPDGEFTEFGLDWAALARLSARLGDRYGPALTPALLSDRRTVRAVAEHIAAAASGPATGTGASGTRPEPEPTHPMLHHAEPDGDGLLFRTRFDGTEPFLRDHRVRDARVLPAVAQLEMARTAVERLLGEGHRGRVRLDDVVWLRPATCGPDGLELSLRVRPLPGQGWEYEIHSVTGDGEPALCSQGRASLTEEGERPPVDLAGLRARCAEHTVAAGAVYELYARAGMDYGPAQQSLAELRVGADEDGRPQVLAELRLPGAAAGLDGCLLHPSLVDGALQATIGLRLPARPDGERQARPALPFAVRHVDAVAATPSTAYVWVRHRPGGGRDAATAPLDVTVVDATGRVCAELTGLNTRALADAPEAQAPAPPEVRGAARPREEVPAAFTPGTGDIAVIGVSGRYPQAADLDAFWRNLREGRDCIREVPPERWDHRRYADAGGSSSGAWGGFLDEIDRFDPLFFQISLHEAELLDPQERLFLQCAHHTLEDAGYAAGPGGKVGVFVGVMYEEYQLYGAQAQYAGRPVALSGSAASIANRVSYFYDFTGPSMTVDTMCSSSLTAIHLACEAIKSGQCETALAGGVNLHSHPNKFLMLSQRRFLSSDGRCRSFGEGGDGYVPGEGVGAVLLKPLERAVADGDHIHGVIKGTALNHGGRTSGYSVPSPAAQAAVITEALTGAGVDPRRLSYLEAHGTGTALGDPIEIAGLKKALHSLGSVPQDLPIGSVKSNIGHAEGAAGIAGVTKVLLQMRHGELAPSLHSATPNPHLALDGTPVRVQQRLEPWHRPVLEADGVRRAVPRIAGVSGFGAGGSNAHVVIAEYEPPAGPPAPPAAPRRTALLVLSARSEEQLVEQSRRLRTRLAELPDDALPDVAWTLQTGRMALEERLALAVTSMADARARLAAFADAPRQPGAWTRGTARRGRDASAGTEAAEVRTAAAEWTGHGTPDRLLRLWADGAAVDWATLDPSAAPVRRVSLPGYPFARERCWFDLEPRDASAAPLSPASAPGAAPPATAEDTGRRDEMILLRPTWTVEEDTPAGEAPAGTFAAHHVVLVGRLTDPERDAVRAALPDGVTCHAADLADGPLERQYTETAQRVLALVRRILADGPRRPVLLQVALVGDAPSGTERERLACFGALAGLLRTASLENPLLHTQYVESLDGASPATVAARLRADAVPGPEPEVRHRDGRRQVGRWEETAPGLAAAAPWRDGGVYLITGGAGGLGLIVAGDIAASVRHATVVLTGRSPLSDDRRRRLEELRAAGLTVDHQRADVGDRESVARVLAHVADRYGPLTGIVHSAGVTDDGLLLRKTPETLARVLAPKVAGLVNLDELTREQPLETFVCFSSIAAAFGNPGQADYAAANAFMDAYAVYRNRLVEAGLRHGRTVSVDWPLWDEGGMGGDTVRENLRAAGLGTLDTPRGLRALRQALAPADGPADGRLLVAVGRRETLPARLFGNAVRASGPADGTPAAAAAADPGRPGVTGAAAADSEQPATLAAAAAPDPEHPGATDAGTARALEERAVGHLRRLLASSLKLGPERLAPDTPLEQYGMDSVIAVHAVTRLEESFGPLSRTLLFEFPTIRDLAEYFVSDHPQALRTLLGEPTAPLPVPATPAAPADPAGAPPPGDTASAPGSGPAVAARDRAAGPGTHRAGGDGDIAVIAVSGRYPQAADLDELWANLRDGKDCVTEVPADRWDPGTADAATDAGEGARSRAWGGFLDGIDRFDPLHFGISPREAAAMDPQLRLFLETVWHLLEESGTTQEVIERRYGRSVGVYVGAAYHLYRADDTDPALAALTSAASYNMIANRVSHFFGLEGPSLAVDGMCASSALAIHLACADLRRGETELAVAGGVNLTVHPDKYLALDELRLLGSHPGSRSFRDGDGYLPAEAVGAVLLKPLEAAVRDGDRILAVVKGTASVHSGRSNGFMMPSHRAQTKAMRRALEQAAVTADSIGYVEAAAGGTTLSDAVEFRALREVFDGVTEPVALGSVKSNLGHPEAASGIAQLTKVVLQLRHGQLAPLVEVGAPNPDLDFDGTALTLCDRLTDWAPRGADGAGGAPAPRRALINSVAAGGSHVSLVVEAPPRTGTATEGAPDNGPQVVVVSARNARRLRTAVRRLHDFLERDGSVTLADVAYGSQLGREALPERLAVVARSLDELKAALAHHLADDPGTDDAPAAVTVHRGNAEEDAGPLGTVLSGLRGEQFVAGLVADRDLDHLAELWVRGVTVPWGGLHAGRRPLVPLPPTEFERGSYWVGRRPGPARPTAAGTAPTDTAAPAGPERAGHGEEAEHAERTELPERAGRLRDRALTDTERTVVAAWSELLEIDTGELDAASNFLSLGGNSLLATRLINLLERHTGVHLPVQAVFDAPRVAELARELERRRPSVPTGSPDTEQILKSIALIEDMSDEELDALLVENVEN
>NZ_CP010849.1|WP_044378971.1|798259_799021_+|3-hydroxyacyl-CoA-dehydrogenase
MRIEGSVALVTGGASGLGLATVRALAERGASVVILGRSARGKEAAQELGERVVFSPGDVTSEEDVTAAIDLASSLGPLRIAVSCAGVGNAFKTVGRKGPFPLAAFDKVIRVNLIGTFNVVRLAAARMDQAEDDGEEERGVIVNTSSAAAYDGQIGQAAYAASKAGIVGMTLPIARDLAPSRIRVVTVAPGLFHTPMFDSFPDSALEALGRQVPHPARLGDPGEFASLVTHIVENPMLNGETIRLDGALRMAPR
>NZ_CP010849.1|WP_052808550.1|799297_800461_+|acyltransferase
MSDEPSAGSRLPSLTSLRFFLALVVVWYHMSFVSGLFDGSLQQSLGIASPFASGAVSGFFVLSGFVLTWAHRPDDRLRAFWRRRWWKIFPNHLLAWTAVLVFFAVTATEVPMPSPPGDGTGAAVANLLLVQGWIPDMSVFSGFNTPAWSIACEAFFYALFPALFVVLRKVPAQRLRRVWVALAVLIVLVPLAASAFPGPDLYDWLPLSERGLWFVYVFPPVRLLEFVLGIVTARLVLTGTWPRVGRLAVTAFFLVFFFMLPGLPAQYAMGSAMAPALAAIIARTALADIEGRARRLPRPALIALGEASYALYITHFPLMLAVRHLIGPDPDLAPGTGFAIVFGLIGLAVALSLVVYRYFESPLMRRWSGGRPPSRPQPAASAAAPAS
>NZ_CP010849.1|WP_044387367.1|800732_801281_+|peptide-methionine-(S)-S-oxide-reductase-MsrA
MTEAQSVNGGTETLTLGPGCFWSFDAVARRTPGITSSVVGFAGDHGPPPDYEAYQRYGLNPQKFVEAVQVTFRPDEISLEEILALFFQSHDPTTPNQSGADHGTVYHSTIFYADEDQRVRSEQVMRRVRRDIGKDIVTDLRPCQQFFEADPEQQDFYGKNPSQPYCRVVIEPKLRTLGLDAG
>NZ_CP010849.1|WP_159392861.1|801713_802826_+|acyltransferase-family-protein
MVFATHVVWYTQLVPGDAGKELREAFALSGSYGVGFFFILSGFVLTWTARSDDTARSFWRRRLAKIGPMHLVTFGLAAILVLSTARPTRAVDWLASLTLQQAWFPSIQTSSAVNGVAWSLACEFFFYLAFPALLPLLRRIRVEWLWPAAGAVLALIAAMFLVATYVVTDQPRLVAFSVSGEVSFTQVWFVYFFPPVRALEFVLGIVLARIVAAGRWPRIGLVPAFALAVAGYVLALYLPYLAGTAGLATVWTAPLIAAAAVADRERAASVFRRPAMVYLGELSFAFYMVHWIVIMTAAELIGPTRTFSLTTGALLVLVLLVVALVASYVLYRCVETPLVRRFGRHRPGTSGTDLPAAPTPLRAEGHRVPE
>NZ_CP010849.1|WP_044378973.1|803187_804510_-|acyltransferase-domain-containing-protein
MTKPATEDVRIGSGAGAVPWVLSGRSAAGLRAQAARLAARLETDSAASVVDEVTEVGRSLVAAGTAHEHRAVVLGRDRADLLLGVRALAEERAAANVVRGRADRRAGAQVRPVFVFPGQGTQWAGMAVGLLDTSPLFAREIRACERALSPYVDWSLEDVLRGVPGTPPLDRVDVVQPVLFSMMVSLARLWHGFGVEPGAAVGHSQGEIAAAHVAGALSLEDAARIVALRSQALTEIRGRGEMLTVLAPNDQVRTMLAAWDGTLSVAAVNGPATMTVSGDLAAMSEFGAALSAAGMMRWRVPGVDFAAHSAHVESLRKTLLDLAAGIGPRPGEVPFYSTVTGRRIDTAELDAEYWYRNLRQTVRFDEAVRALLADGHKVFIECSAQPVLTVGMQDTVEQLGGSAVLMATLRNEDGGTDRFLAALAEAYVNGVAVDWTPAFA
>NZ_CP010849.1|WP_052808553.1|804829_806092_+|hypothetical-protein
MVEEAVVRVGSGATGWAIENSRQLLAELTGEPFARFDRTAGSETRLVEATALWVVLRLSGVKAITGLLSAELTHVIRERISDDMTVDLLLRYVRATHASFTRELFERCEVLVPTEDRPAVMRSISADLFEGMETLSAAVAEKFAAERTRWFAGSVGERFELVSDILKGEPVDTRKTMRRLRYELTLHHLALVLWQDEIGVGGTRELETTAVRLLNQAGCSSALLLPAGPGRLWAWGGRASDHPGELRRVDDPVDLPAHVHVASGLPGHGVAGFRRSHQQAITAERIGRITGPGPSALCDYGDLELVILLGNDAEATADFVRRELGPLAADNRTMAALRETVRCLLDNERAVAVTAKHLHIAKNTVVYRVKKAEQLLGRSLHEDHLRLHLALYLAERLGSSVLGEQGPATGLENSIRAVSR
>NZ_CP010849.1|WP_052808554.1|806088_807567_+|hypothetical-protein
MSDGQTNKNEKLLDYLKWVTADLQKARARVEELESSRSEPIAVLGMGCRYPGDVSTPEELWRVAADGVDAITGFPTDRGWDVEGMYDPDPDAVGKFSAREGGFLSDIKGFDAAFFGISPREALAMDPQQRLLLETTWEAVERARMDPRSLRGSDTGVFVGVMYTGYASMVDAASTGTEGYAMTGMLTSVASGRISYVLGLEGPTVSMDTACSSSLVSIHHAVTALRNGECSLALAGGAMAIPVPDGFVEFSRQRGLAPDGRCKAFAAAADGTGWSEGVGMLVLARLSEARRRGLPVLAVIRGSAVNSDGASNGLTAPNGPSQQRVIRQALANAGLSPAEVDVVDAHGTGTRLGDPIEAQALLATYGQSRPEGQPLLLGSLKSNIGHTQAAAGVAGVIKLVMAMRHGVVPATLHVDEPTPAVDWSAGSVERVTEARPWPETGRPRRAAVSSFGVITSYSIHYTKVYEYEVFPVFASAFDRITSYNVCYTKLLW

Crispr_ID: NZ_CP010849_3

• CRISPR_ID: NZ_CP010849_3
• CRISPR_location: 811259-811375
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_3

Consensus_repeat	Method
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAC	CRISPRCasFinder

spacers of NZ_CP010849_3

>3.1|811302|31|NZ_CP010849|CRISPRCasFinder
GTCGTCGGCTCGCCGGGGCAGGCCAACTACT

CRISPR arrays and Neighbor proteins around NZ_CP010849_3

CRISPR arrays

The CRISPR arrays of NZ_CP010849_3

>merge|NZ_CP010849|3|811259-811375|CRISPRCasFinder
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGACGTCGTCGGCTCGCCGGGGCAGGCCAACTACTCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAC

>NZ_CP010849|3|3|811259-811375|CRISPRCasFinder
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAC	GTCGTCGGCTCGCCGGGGCAGGCCAACTACT
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044378973.1|803187_804510_-|acyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|214838
NZ_CP010849.1|WP_044378971.1|798259_799021_+|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|187629
NZ_CP010849.1|WP_052808550.1|799297_800461_+|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_CP010849.1|WP_044378984.1|829327_830833_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP010849.1|WP_044387367.1|800732_801281_+|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl|CDD|237597
NZ_CP010849.1|WP_052808553.1|804829_806092_+|hypothetical-protein	unknown	unknown	gnl|CDD|225306
NZ_CP010849.1|WP_078969041.1|842396_844475_-|hypothetical-protein	unknown	unknown	gnl|CDD|238429
NZ_CP010849.1|WP_044378988.1|852880_853972_-|HAD-IIIC-family-phosphatase	unknown	unknown	gnl|CDD|273757
NZ_CP010849.1|WP_078969040.1|840012_842721_-|acyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|214838
NZ_CP010849.1|WP_159392865.1|827922_829125_-|hypothetical-protein	unknown	unknown	gnl|CDD|173848
NZ_CP010849.1|WP_159392863.1|808433_810956_+|acyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|214838
NZ_CP010849.1|WP_052808558.1|833776_839860_-|KR-domain-containing-protein	unknown	unknown	gnl|CDD|225858
NZ_CP010849.1|WP_159392861.1|801713_802826_+|acyltransferase-family-protein	unknown	unknown	gnl|CDD|224748
NZ_CP010849.1|WP_052808554.1|806088_807567_+|hypothetical-protein	unknown	unknown	gnl|CDD|238429
NZ_CP010849.1|WP_052808560.1|850930_852793_-|hypothetical-protein	unknown	unknown	gnl|CDD|276938
NZ_CP010849.1|WP_159392862.1|807542_807857_+|hypothetical-protein	unknown	unknown	gnl|CDD|214836
NZ_CP010849.1|WP_159392862.1|807832_808147_+|hypothetical-protein	unknown	unknown	gnl|CDD|214836
NZ_CP010849.1|WP_044387377.1|830902_833719_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|227325
NZ_CP010849.1|WP_063856789.1|819416_827672_-|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NZ_CP010849.1|WP_052808556.1|811466_813350_+|KR-domain-containing-protein	unknown	unknown	gnl|CDD|273787

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044378973.1|803187_804510_-|acyltransferase-domain-containing-protein	gnl|CDD|214838	smart00827, PKS_AT, Acyl transferase domain in polyketide synthase (PKS) enzymes.	1.72309e-121
NZ_CP010849.1|WP_044378971.1|798259_799021_+|3-hydroxyacyl-CoA-dehydrogenase	gnl|CDD|187629	cd05371, HSD10-like_SDR_c, 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs. HSD10, also known as amyloid-peptide-binding alcohol dehydrogenase (ABAD), was previously identified as a L-3-hydroxyacyl-CoA dehydrogenase, HADH2. In fatty acid metabolism, HADH2 catalyzes the third step of beta-oxidation, the conversion of a hydroxyl to a keto group in the NAD-dependent oxidation of L-3-hydroxyacyl CoA. In addition to alcohol dehydrogenase and HADH2 activites, HSD10 has steroid dehydrogenase activity. Although the mechanism is unclear, HSD10 is implicated in the formation of amyloid beta-petide in the brain (which is linked to the development of Alzheimer's disease). Although HSD10 is normally concentrated in the mitochondria, in the presence of amyloid beta-peptide it translocates into the plasma membrane, where it's action may generate cytotoxic aldehydes and may lower estrogen levels through its use of 17-beta-estradiol as a substrate. HSD10 is a member of the SRD family, but differs from other SDRs by the presence of two insertions of unknown function. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	6.16183e-128
NZ_CP010849.1|WP_052808550.1|799297_800461_+|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	2.26464e-27
NZ_CP010849.1|WP_044378984.1|829327_830833_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.23191e-60
NZ_CP010849.1|WP_044387367.1|800732_801281_+|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl|CDD|237597	PRK14054, PRK14054, peptide-methionine (S)-S-oxide reductase.	1.05873e-48
NZ_CP010849.1|WP_052808553.1|804829_806092_+|hypothetical-protein	gnl|CDD|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.94782e-19
NZ_CP010849.1|WP_078969041.1|842396_844475_-|hypothetical-protein	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	0
NZ_CP010849.1|WP_044378988.1|852880_853972_-|HAD-IIIC-family-phosphatase	gnl|CDD|273757	TIGR01686, modular_polyketide_synthase, FkbH-like domain. This model describes a domain of a family of proteins of unknown overall function. One of these, however, is a modular polyketide synthase 4800 amino acids in length from Streptomyces avermilitis in which this domain is the C-terminal segment. By contrast, the FkbH protein from Streptomyces hygroscopicus aparently contains only this domain. The remaining members of the family all contain an additional N-terminal domain of between 200 and 275 amino acids which show less than 20% identity to one another. It seems likely then that these proteins are involved in disparate functions, probably the biosynthesis of different natural products. For instance, the FkbH gene is found in a gene cluster believed to be responsible for the biosynthesis of unususal "PKS extender units" in the ascomycin pathway. This domain is composed of two parts, the first of which is a member of subfamily IIIC (TIGR01681) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. All of the characterized enzymes within subfamily III are phosphatases, and all of the active site residues characteristic of HAD-superfamily phosphatases are present in this domain. The C-terminal portion of this domain is unique to this family (by BLAST).	7.59985e-122
NZ_CP010849.1|WP_078969040.1|840012_842721_-|acyltransferase-domain-containing-protein	gnl|CDD|214838	smart00827, PKS_AT, Acyl transferase domain in polyketide synthase (PKS) enzymes.	2.30343e-113
NZ_CP010849.1|WP_159392865.1|827922_829125_-|hypothetical-protein	gnl|CDD|173848	cd01159, NcnH, Naphthocyclinone hydroxylase. Naphthocyclinone is an aromatic polyketide and an antibiotic, which is active against Gram-positive bacteria. Polyketides are secondary metabolites, which have important biological functions such as antitumor, immunosupressive or antibiotic activities. NcnH is a hydroxylase involved in the biosynthesis of naphthocyclinone and possibly other polyketides.	2.94011e-77
NZ_CP010849.1|WP_159392863.1|808433_810956_+|acyltransferase-domain-containing-protein	gnl|CDD|214838	smart00827, PKS_AT, Acyl transferase domain in polyketide synthase (PKS) enzymes.	3.62808e-93
NZ_CP010849.1|WP_052808558.1|833776_839860_-|KR-domain-containing-protein	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP010849.1|WP_159392861.1|801713_802826_+|acyltransferase-family-protein	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	6.96195e-25
NZ_CP010849.1|WP_052808554.1|806088_807567_+|hypothetical-protein	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	0
NZ_CP010849.1|WP_052808560.1|850930_852793_-|hypothetical-protein	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	6.59641e-47
NZ_CP010849.1|WP_159392862.1|807542_807857_+|hypothetical-protein	gnl|CDD|214836	smart00825, PKS_KS, Beta-ketoacyl synthase. The structure of beta-ketoacyl synthase is similar to that of the thiolase family and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.	1.00664e-27
NZ_CP010849.1|WP_159392862.1|807832_808147_+|hypothetical-protein	gnl|CDD|214836	smart00825, PKS_KS, Beta-ketoacyl synthase. The structure of beta-ketoacyl synthase is similar to that of the thiolase family and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.	1.00664e-27
NZ_CP010849.1|WP_044387377.1|830902_833719_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|227325	COG4992, ArgD, Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism].	1.81065e-56
NZ_CP010849.1|WP_063856789.1|819416_827672_-|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP010849.1|WP_052808556.1|811466_813350_+|KR-domain-containing-protein	gnl|CDD|273787	TIGR01746, L-aminoadipate-semialdehyde_dehydrogenase, thioester reductase domain. This model includes the terminal domain from the fungal alpha aminoadipate reductase enzyme (also known as aminoadipate semialdehyde dehydrogenase) which is involved in the biosynthesis of lysine, as well as the reductase-containing component of the myxochelin biosynthetic gene cluster, MxcG. The mechanism of reduction involves activation of the substrate by adenylation and transfer to a covalently-linked pantetheine cofactor as a thioester. This thioester is then reduced to give an aldehyde (thus releasing the product) and a regenerated pantetheine thiol. (In myxochelin biosynthesis this aldehyde is further reduced to an alcohol or converted to an amine by an aminotransferase.) This is a fundamentally different reaction than beta-ketoreductase domains of polyketide synthases which act at a carbonyl two carbons removed from the thioester and forms an alcohol as a product. This domain is invariably found at the C-terminus of the proteins which contain it (presumably because it results in the release of the product). The majority of hits to this model are non-ribosomal peptide synthetases in which this domain is similarly located proximal to a thiolation domain (pfam00550). In some cases this domain is found at the end of a polyketide synthetase enzyme, but is unlike ketoreductase domains which are found before the thiolase domains. Exceptions to this observed relationship with the thiolase domain include three proteins which consist of stand-alone reductase domains (GP|466833 from M. leprae, GP|435954 from Anabaena and OMNI|NTL02SC1199 from Strep. coelicolor) and one protein (OMNI|NTL01NS2636 from Nostoc) which contains N-terminal homology with a small group of hypothetical proteins but no evidence of a thiolation domain next to the putative reductase domain. Below the noise cutoff to this model are proteins containing more distantly related ketoreductase and dehydratase/epimerase domains. It has been suggested that a NADP-binding motif can be found in the N-terminal portion of this domain that may form a Rossman-type fold.	5.20974e-103

Protein sequences

>NZ_CP010849.1|WP_159392863.1|808433_810956_+|acyltransferase-domain-containing-protein
MFGGRGLDETGWTQPGLFAVEVALFRLVESWGVRPDFVTGHSVGELAAAHVAGVLSLGDACRVVAARGRLMQALPSGGVMVAVEAGEAEVAQVLRGRESLVGIAAVNGPSSVVVSGAAGVVEEVVAVLRRRGCRTRRLSVSHAFHSPLMDPVVEEFASVVGAVELAEPVIAMAGGEGVCSARYWAEHVRRPVRFADHVVWLRERGVTRFVEVGPEGVLSALGPQSAPDAVFVALQQREGSQVRGVLTGLARLHTVGHTVDWSRLFTGTDAALVDLPTYPFQHQPYWLDSTSPGARNAAGLGLAAPGHPLLTTAVELAGDDGAVFTGRLALHTHPWLADHRVDGAVTLPSAALAELAVRAGDETGRSHLADLTIDTPLTVPDGGAVHVRVTVGAAGEDQYRRFTIASRPDRDDPAAWEVHATGLLAEQPPAPEVRFESWPPPGAAPAGLDGFYDRLAGKGHTHGPVFQGLRALWQRGEELFAEVRLPDETEPDTFGIHPALLDSALHPLLADGQDTTGLSWHGFSLYATGSRTLRVWVRPKGQDAFRLWLADESGEPVAEVRALRPRPVAPVGRSGGVRDQSLFHVAWSPVTLPDPEDLAPTRWAALRHTPPDGPAHRVENVADAAGQTLVARLGEAAGDDTAGAAHRTALRALELVQDALACGTSRLVLVTENAVATHDGEDVELGSAPVWGLVRSAQAENPGRITLIDLDGSPASAERLTAAIASGHDQLAIRAGRASTPRLARVRTAAAAGPEPDPDGTVLVTGGTGALGALFARHLVTHHGVTRLLLTSRRGPDAPGAQDLAAELTALGATVRIAACAAADRTALAALLDTVSYNFV
>NZ_CP010849.1|WP_159392862.1|807832_808147_+|hypothetical-protein
MLYEVIMVIKLVMAMRHGVVPATLHVDGPTPAVDWSAGSVERVTEARPWPETGRPRRAAVSSFGVITSYSIHYTKVYEYEVFPVFASAFDRITSYNVCYTKLLW
>NZ_CP010849.1|WP_159392862.1|807542_807857_+|hypothetical-protein
MLYEVIMVIKLVMAMRHGVVPATLHVDGPTPAVDWSAGSVERVTEARPWPETGRPRRAAVSSFGVITSYSIHYTKVYEYEVFPVFASAFDRITSYNVCYTKLLW
>NZ_CP010849.1|WP_052808554.1|806088_807567_+|hypothetical-protein
MSDGQTNKNEKLLDYLKWVTADLQKARARVEELESSRSEPIAVLGMGCRYPGDVSTPEELWRVAADGVDAITGFPTDRGWDVEGMYDPDPDAVGKFSAREGGFLSDIKGFDAAFFGISPREALAMDPQQRLLLETTWEAVERARMDPRSLRGSDTGVFVGVMYTGYASMVDAASTGTEGYAMTGMLTSVASGRISYVLGLEGPTVSMDTACSSSLVSIHHAVTALRNGECSLALAGGAMAIPVPDGFVEFSRQRGLAPDGRCKAFAAAADGTGWSEGVGMLVLARLSEARRRGLPVLAVIRGSAVNSDGASNGLTAPNGPSQQRVIRQALANAGLSPAEVDVVDAHGTGTRLGDPIEAQALLATYGQSRPEGQPLLLGSLKSNIGHTQAAAGVAGVIKLVMAMRHGVVPATLHVDEPTPAVDWSAGSVERVTEARPWPETGRPRRAAVSSFGVITSYSIHYTKVYEYEVFPVFASAFDRITSYNVCYTKLLW
>NZ_CP010849.1|WP_052808553.1|804829_806092_+|hypothetical-protein
MVEEAVVRVGSGATGWAIENSRQLLAELTGEPFARFDRTAGSETRLVEATALWVVLRLSGVKAITGLLSAELTHVIRERISDDMTVDLLLRYVRATHASFTRELFERCEVLVPTEDRPAVMRSISADLFEGMETLSAAVAEKFAAERTRWFAGSVGERFELVSDILKGEPVDTRKTMRRLRYELTLHHLALVLWQDEIGVGGTRELETTAVRLLNQAGCSSALLLPAGPGRLWAWGGRASDHPGELRRVDDPVDLPAHVHVASGLPGHGVAGFRRSHQQAITAERIGRITGPGPSALCDYGDLELVILLGNDAEATADFVRRELGPLAADNRTMAALRETVRCLLDNERAVAVTAKHLHIAKNTVVYRVKKAEQLLGRSLHEDHLRLHLALYLAERLGSSVLGEQGPATGLENSIRAVSR
>NZ_CP010849.1|WP_044378973.1|803187_804510_-|acyltransferase-domain-containing-protein
MTKPATEDVRIGSGAGAVPWVLSGRSAAGLRAQAARLAARLETDSAASVVDEVTEVGRSLVAAGTAHEHRAVVLGRDRADLLLGVRALAEERAAANVVRGRADRRAGAQVRPVFVFPGQGTQWAGMAVGLLDTSPLFAREIRACERALSPYVDWSLEDVLRGVPGTPPLDRVDVVQPVLFSMMVSLARLWHGFGVEPGAAVGHSQGEIAAAHVAGALSLEDAARIVALRSQALTEIRGRGEMLTVLAPNDQVRTMLAAWDGTLSVAAVNGPATMTVSGDLAAMSEFGAALSAAGMMRWRVPGVDFAAHSAHVESLRKTLLDLAAGIGPRPGEVPFYSTVTGRRIDTAELDAEYWYRNLRQTVRFDEAVRALLADGHKVFIECSAQPVLTVGMQDTVEQLGGSAVLMATLRNEDGGTDRFLAALAEAYVNGVAVDWTPAFA
>NZ_CP010849.1|WP_159392861.1|801713_802826_+|acyltransferase-family-protein
MVFATHVVWYTQLVPGDAGKELREAFALSGSYGVGFFFILSGFVLTWTARSDDTARSFWRRRLAKIGPMHLVTFGLAAILVLSTARPTRAVDWLASLTLQQAWFPSIQTSSAVNGVAWSLACEFFFYLAFPALLPLLRRIRVEWLWPAAGAVLALIAAMFLVATYVVTDQPRLVAFSVSGEVSFTQVWFVYFFPPVRALEFVLGIVLARIVAAGRWPRIGLVPAFALAVAGYVLALYLPYLAGTAGLATVWTAPLIAAAAVADRERAASVFRRPAMVYLGELSFAFYMVHWIVIMTAAELIGPTRTFSLTTGALLVLVLLVVALVASYVLYRCVETPLVRRFGRHRPGTSGTDLPAAPTPLRAEGHRVPE
>NZ_CP010849.1|WP_044387367.1|800732_801281_+|peptide-methionine-(S)-S-oxide-reductase-MsrA
MTEAQSVNGGTETLTLGPGCFWSFDAVARRTPGITSSVVGFAGDHGPPPDYEAYQRYGLNPQKFVEAVQVTFRPDEISLEEILALFFQSHDPTTPNQSGADHGTVYHSTIFYADEDQRVRSEQVMRRVRRDIGKDIVTDLRPCQQFFEADPEQQDFYGKNPSQPYCRVVIEPKLRTLGLDAG
>NZ_CP010849.1|WP_052808550.1|799297_800461_+|acyltransferase
MSDEPSAGSRLPSLTSLRFFLALVVVWYHMSFVSGLFDGSLQQSLGIASPFASGAVSGFFVLSGFVLTWAHRPDDRLRAFWRRRWWKIFPNHLLAWTAVLVFFAVTATEVPMPSPPGDGTGAAVANLLLVQGWIPDMSVFSGFNTPAWSIACEAFFYALFPALFVVLRKVPAQRLRRVWVALAVLIVLVPLAASAFPGPDLYDWLPLSERGLWFVYVFPPVRLLEFVLGIVTARLVLTGTWPRVGRLAVTAFFLVFFFMLPGLPAQYAMGSAMAPALAAIIARTALADIEGRARRLPRPALIALGEASYALYITHFPLMLAVRHLIGPDPDLAPGTGFAIVFGLIGLAVALSLVVYRYFESPLMRRWSGGRPPSRPQPAASAAAPAS
>NZ_CP010849.1|WP_044378971.1|798259_799021_+|3-hydroxyacyl-CoA-dehydrogenase
MRIEGSVALVTGGASGLGLATVRALAERGASVVILGRSARGKEAAQELGERVVFSPGDVTSEEDVTAAIDLASSLGPLRIAVSCAGVGNAFKTVGRKGPFPLAAFDKVIRVNLIGTFNVVRLAAARMDQAEDDGEEERGVIVNTSSAAAYDGQIGQAAYAASKAGIVGMTLPIARDLAPSRIRVVTVAPGLFHTPMFDSFPDSALEALGRQVPHPARLGDPGEFASLVTHIVENPMLNGETIRLDGALRMAPR
>NZ_CP010849.1|WP_052808556.1|811466_813350_+|KR-domain-containing-protein
MFVLFSSVAGVVGSPGQANYSAANHFLDALAQHRRANGLPAHSLAWAAWAQRHGMASRLSDVDWNRATQSGLRPIEPAEGPELFDAALACGHPTTVPMHLDVALIERQPGPVLPVLRGLVRRPARRVVTAAAEHTGLLAERLAPLDVSGRRELLLDLVRTAAAAVLGHSGTDGIAATTAFSALGFDSLTAVELRNRLEAETGLRLPPTLLFDHDSPAALIEYLGTELASRAEPPAPAAVDFAAEVRLAEDVVPARDVTTVVTDPGQVFLTGATGFVGAFLLRDLMRSTRATVHCLVRGADEATALDRLRANLTWYGIWDEIDRERLSVLTGDLAAPRFGLGAERFDRLAREIDVVYHAGATVNWLHPYTSLKAANVTGTEEALRLAALHRTVPLHYVSSTGVFAKPAPGGRGLAPQDPTGPPEELTNGYRQSKYVAEKIIDLARERGLPVSVYRADVVSGAQTNGACQTRDFVWLSLKGSLQAGAVPAGADALFPMVPVDYVSAAVVALSRTADGETFHLFNPVAVGFAEMVARLRASGHVLDEVPWDDFVATVRADRDNALFPVIDIFRSYMTAGEALYMRMDVSATEAALAGTGITCPEIDADLFGRYARFFTDSGYFPAPVEPA
>NZ_CP010849.1|WP_063856789.1|819416_827672_-|type-I-polyketide-synthase
MRRIAVVGLACRFPGAGDGPAFWRLLRDGTDAVREAPQDRWQGAGLPHRLGGFVDGIDRFDAAFFGISPREAAAMDPQQRLMLELAWEALEDARIVPARLAGGDTGVFVGVMWDDYAALQDRLGAAGVGRHTMTGTRRGIIANRVSHHLGLRGPSLTVDTAQSSSLVAVQLACESLRRGECDVAIAGGVNLNILAEPTLGAVRFGGLSPDGRCHTFDARANGFVRGEGGGAVVLKPLAAALADGDDIYCVLSGGAVNNDGAGEGEHTGLTVPSRSAQEQVVRRAYRRAGVAARDVQYVELHGSGTTVGDPIEAAALGAALGRARQPGAPLPVGSVKTNIGHLEGAGGIAGLLKVALSIRHRMLPPSLHFATPHPDIPLDELRLRVQTELTPWPEPDRPLVAGVSSFGMGGTNCHLVVAEPPAPAPPAGGAREPGASAWPLSGRTGEALRAQAARLLSFVDERAEPAADIGLSLATTRTAFRHRAVVIGADRAGLRRRLADFAAGGAVAGVVEGQATVTGKVVFVFPGQGAQWAGMAAGLLDAVPEFAASMRACEEAFAPYVDWSLAEVLRDPAALERVDVVQPALFAVMVSLAALWRSCGVEPAAVVGHSQGEIAAACVAGALSLKDAARVVTLRSRALSALSGRGGMVSVLRPAGEVRDRIAEWEGAVSLAAANGPSSVVLAGDPGALDELVARWTREGVETRRIAVDYASHSPQVEQIRERLHTVLDGIGPRTSPVPFYSTVTGDVLDTAGLDAAYWYRNLRQTVELERAAGALVRDGHAVFVECSPHPVLLPALRETLERAGLESAAVTGSLRRGEGGPERFLASLAELHVRGVAVDWSRVFALRGARTVGLPTYAFQRERHWLTGTGVPAAAPATPPPVAAPAQDTPRAGNPAATPAGPGMLGLVRSALAVVLGHAGGDAVDPGTTFKELGVDSLSAVELRDRLSAATGLTLPAGVLFGHPTPAELSDHLRELASGGEQSTAPAATAASDEPVAIVGMACRLPGGVASPEDLWRLVVDGTDAISEFPANRGWDIGRLYDPDPDRAGTTYTRHGGFLHDADQFDAEFFGISPREALAMDPQQRLLLETSWEALERAGIDPVGRRGTPVGVFVGAMAQDYGPRLHAAHTESDGYRLTGSTISVASGRIAYTLGLQGPAVTVDTACSSSLVALHLAARSLRAGECSLALAGGVAVMSGPGMFVEFSRQRGLAEDGRCKAFSAAADGTGWAEGAGIVVLERLSEARRNGHRVLAVVRGSAINQDGASNGLTAPNGAAQERVIRQALAAAGVSAGDVDVVEAHGTGTTLGDPIEAGALAAAYGRGRDPGRPLLLGSLKSNIGHAQAAAGVAGVIKTVQALRHGVVPGTLHADEPTPHVDWAAGALELVTGAREWPRTGRARRAGVSSFGISGTNAHVIIEQAPPEPGTGPEPRPESAPEPGPETGEQAGPVLPWVLSASSREALAAQAAALLSFADARPGLDRADTGFSLAAARSGLPHRAAVVGTDLSALRRGLTALAAGAEAPGVVRGTAGPTGGVVFVFPGQGSQWAGMAVDLLDSSPVFAASMLACAEALAPHVDWDLFQVLRDPAALERVDVVQPALFAVMVSLAALWRSYGVEPDAVVGHSQGEIAAACVAGALGLADAAKVVALRSKAILALSGAGGMVSVALSEDETAARLLRWDGRLSVAVVNGPGSVVVAGDPDALAELAAECESAGVRCKRLPVDYASHSAHVERIEDELARVLAGLTPRPSAIPFYSTVTAGVLDTTGLDGGYWYDNLRQKVRFAETVGLLAEQGHAVFIEVSPHPVLTAAVEDVREGAAAVGSLRRDDGGLARFTTSLAEAYVRGVAPDWRAVFPGARQTDVPASVFLRRRYWLDPVPDGGPADVEAAGLDAAGHPLLGAVVELPDSGGLVLTGRLSRAAQPWLADHGLGDLVLLPGAAFVELAVRAGDEVGCDRVAELTCEVPLVLPPHGAVAVRVTVGEEDASGRRELAVHARPDDGPGRWRRHASGVLASGPAEEFDLAAWPPPGAVPVEWDGGYDRWTELGYRYGPAFRGLRAWWRRGEEIFAEVALPPQTEADAGRFGLHPALLDAALHAAVADGPDPRLPFSWQGVTLRATGARALRVRISPDGADAVTLRLADTTGAPVASVESLALRPLPAGEPAAGPPDALFRVDWAEARLPDTRDAARPWAVLGADTFGIGGPCHAGLGALAAAGAVPQVVAAALTGPPTADGAHAVAGRALRLMQEWLADERFAGSRLVLLTRNAVVVDPAEADDSGLAGAGVWGMVRSAQREHPDRFVVADLDGHEASAAALPDALATGEPQLALRKGRAMAPRLARVTARPAARPALADGTVLVTGATGTLGGLFARHLVSRYGVSHLLLAGRRGPDAPGAAELAADLTGLGATVTVAACDVADRDALAALLASVPAEHPLTGVVHAAGLLDDSVLEAMRPEQLERVLRPKADAALHLHELTRGHDLALFVLFSSAAGILGLPGQANYAAANAFLDTLAQRRAARGLPAVSLAWGLWARASGMTGHLADADLSRMRRAGLAPLSSAEGLALFDAAVSCGEALLVPARLEPAAVRAGGAVPALLRGVVRARVRRAEAAGEPGGPAPLGDRLAGMSAADREEALLGLVREHTATVLAHGTPGAVEPGRTFKELGFDSLTAVELRNRLGAATGLRLRATLVFDYPTPSALAAHLAAALGPAGPAPAASLAEPPGRPAGELDGLELDELFHLIDGELGTS
>NZ_CP010849.1|WP_159392865.1|827922_829125_-|hypothetical-protein
MTAVTGERAGETTGPAVGPAELVARARELAPLIREHAVKTEQDRRLAEEVVVALREAGMFRLTTPARFGGYELRMPDLISIIVEVGKACGSAGWNLSIDTASTRFALNAMPETALSDMFEGNPDAYVISTAHLSTTKAYRAEGGYRVTGTFPWSSGCEIADWAYIPVVHIHDGDEQTADLVGVVVPMSDLRIERTWHSAGLAGSGTHTVVAEDVFVPERRATAFSLTDLVGEDERDSMLIQGSVQSLAAIVGAAQGAVEVTRQALDKKRPITYVNYEAAADAPSVQMWFAEATHLIETAQLHLREIGTVLDGVPETQPMPWVERARLRMHERSAQEKSRAGVEKLLDVVGGSAFALSNPLQRLWRDISVMSRHTALNAPIIVEDYSRAVLDVHPSVTLLY
>NZ_CP010849.1|WP_044378984.1|829327_830833_-|MFS-transporter
MSESADTGSKVAAEGPPDPHYANRWRILAVIGVAQLTIFLDTTVVNIALPSAQADLGFGDGDRQWVVTAYALAFGSLLLLGGRVVDLVGAKRSLMISIIGFGVTSVLGGAANGFAMLVTARALQGAFAALVAPAALSFLLTVFKDPKERVKAFGVYGALGSGGLALGLVLGGALTDWLDWRWCLYVNVFFTAAVFVGALVTMRNRQSDHRPDKLDLPGTVTASVGLFCLAYGLSNADDGKWGGADVWGFLLASGVLLVAFVLFELRSRTPLLPIRIVLHRNRGSAYLAMFLLGIGLFVQFLFLTYYLQLILDFSAIQSGLAFLPMIVGIAIGATTIPPVLEPKLGTRVLVPAGLVLAAVGSFWLARLTTESSYAGGVLAPSLIAGVGFGLVVSLGAAVATVGVEPQDAGAASALVNTVQQVGGSIGTALLSTLAITAANTFVEGKSPTPHLAAEAAVESYTTAFFWGAVVFLGGAVVCGLLFDRHVTAQADPEVGAPAAVV
>NZ_CP010849.1|WP_044387377.1|830902_833719_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme
MLGTFGLDVEYVRAEKNTLYHLDDSGAEVPVLDLVGGWGSLMLGHNHPEITAYAKELLDTGWPVHSQHSAHPVADRVGAVLNGILAREFPGAEPYSVIFANSGAEAVEAAVKHCEFDRALRVKSLFEEIEWHAGTALTAVRAGTAALPDDTSLLPGDVPAPATADEFQALLGAVAAHNMGRAATSPVFFALERAFHGKLVGSTQFTYNPLFRAAFATLGPAVRFVPPNDAAAFEKAVAEERVTVLDVEVADGRVTLVERAFPVVAGLIVEPIQGEGGIQELTGEFAARVRRICDEIQCPVVVDEIQTGMGRTGKFFASSHIGLLGDYYLLGKSLGGGIGKTSAMLVRQSRYRPEFELVHSSTFAKDGFSTAIALRTLELLEAEDGAAYDRAAERGERILAMLRELAREFPDVVADVRGKGLLIGFEFADQSQASSPVIREKALAGLLVFQLGSYLQLAHRIRTGPTASVPTMLRIEPSIHISDEEIAQLRTGLTEVCRILRHQDALPLVLPLTGAAQARSPRAEIRDFRPAAGEAVAPAEPAARKAGLVSYPLTPDLLREFDPSLADLDDERLLAYARRSELLRDLPACTPVRFDSPQGTSVELTVYPLLVSQEQLREYQVLGQTFLIGLDLDRRVRAAKADGCDSVGLGFGLGAVSGHGRALRVSGVTVSTGSALAVGSALAAVRGAADERFGGLDGLTLAVVGGGGHIGSALGAIGAGQASRIVLVGSGRAGSAERLRAAERRIYQEAWARIAAGGELAGIPAALAAEPLVAGWLAEGRAGDEPSGEAIAAYLDEAYPANPFVVATDDLLSVRNAQVVFSAHSSPVPVLDEKLLADGAVLCDMSFFGTGAESATVISREDLRYVRGGVLSVPERGILLRGFGASPGAGELSAGAAEAITLALSGSDGTMGNGPLTRERVDAIVDLAKQHGFETIST
>NZ_CP010849.1|WP_052808558.1|833776_839860_-|KR-domain-containing-protein
MYAIRSYYDHGVTRLLLTSRRAPAAPGAQDLAAALTALGAPVRIAACDAPARTALAALLDAVPPQHPLTGVVHPAGVLHAGIVTALTPDRLAAVLRPKADAAWHLHELTRDHPLTMFVLFSSLAGTLGNPGQANYAAANHVLDALAQHRHAHGLPAVSLGWGLWAAEGGMQTGATEAGHLRHTGVRPLDAQAGTALFDRALALGRPVTLPARLDLRTLRAGPAPVPAMLRGPAGRPARRVVRPGAGDAGPLAERLAALPRHERQEQIADLVRAEVAAVLGFGAGERISETLPFRELGFDSLTAVELRNRLAETTGLRLSPGVVFDHPTVPALADHLLSELSGDLPDPAAAAPAAGPAGADEPVAIVGMACRFPGGAGTPEALWRLVADGVDAISEMPDDRGWDIERLWDPDPDKPGTFYPRAGGFVYDAAEFDAGFFGISPREALAMDPQQRLLLETSWEALENGGIDPVSLRGSDTGVYTGLTAQEYGTGADAAEAGAEGYLLTGSTTSFGSGRISYTLGLEGPTMSIDTACSSALVSVHLAAGALRGGECSLALAGGATVMAQPIGFIEFSRQRTLAPDSRSKAFAESADGTGWSEGVGVFVLERLSDARRNGHPVLAVLRGSAVNSDGASNGLTAPNGPSQQRVIRQALANAGLAPSEVDLLEAHGTGTRLGDPIEAEALMATYGRDRPAGRPLWLGSVKSNIGHTQHAAGAGGLIKAVMALRHGLMPKTLHVDQPTSAVDWSSGAVELLTEARPWPELDRPRRAAVSAFGMSGTNAHVIVEEAPDEPAPAPAAVSLPVVPWVLSAKSPQALRAQATRLLALVDSGTAPDPLDIGYSLATRTVFDHRAVLVTGGGAQASAGLRAIAEGEAPAAADGRTAFLFTGRSADGFHRDLYAASPVYAEAFDELLAGLGTQGEEATALAAEVALFRLLESWGVAFGCVAGTGIGEAAAAYVAGALPAADAGRLVTAGERAGVTCAAPRIPVVSLRTGRPLAAGDPLGTAGTEGTAAAERWMAEHRVTRFAESGTGRLLDGSVLLRQDGRPGLHAVLDGVGELFVAGAAVDWAAVFTGTGARRTALPTYPFQRERYWPAGPGDTGPRGRDATEHALLGAPVAVAGRDELVFTSHLSLTTHPWLAEHVVGGVPVLSGPALVDLAIRAGDTAACPELAELTVTEPLVLPGEGGLRLQVVTGAPGEAGRRTVAIYTRPADGPDDGAAGEWTCHATGTLAPGTARPEADPAVWPPAGAAPVDWGYEDLADAGHRYGPLFQGLKSVLRRGEELFAEVRLPERAAAGAGGFGIHPALLEAAVQPLLLGAADVAPDGTARLPLAWEGVALHAGEATVLRVRLTPAGPDAFRLDAVDEAGMPVLTAESVRPAPVRLTRREGTAPASSAAASLFTLRWTPVAPVDEDEPESLLALLGEDTGGLAALAPLRFGGIEEAVASYTPWDVLLAQPSRPGTAGDRAAEAHRAVRSALDAAQSWLAQENLPDNRLVVVTRGAMAVEAEDDVLDPAGAAVWGLLRSAQAENPDRIVLVDLDDDPASAELLFVAAQTREPQLAIRAGRMLAPRLAAAAPPAREPAVPPVPVVAGGTVVVTGADGPLGALFARHLVTAHGVRHLVLACPQGTDSPAARLAEELAALGATARVAACDPADRAAVREMLADIPPGHPLTGIVHTENALDDGVFTALTAERVARVLRPKADGAWHLHELTADAPPPLFVLFSSVVGMLGSPGQANFAAANAFLDALAAHRRAGGLPAVSVAWGRMVDGGQSGLRMIAGDEACELFDAALATGHAVVAPAPLDLAALRRGTAQVPAVLRALVPRGERRRASAGRPADRFAQLTRAEAETRLRELVRAEAAGVLGHATPENLQWEVSFRDSGFDSLSAVQFRNRLSEQTGLSLPTTLVFDYASPGVLVDHLLERLAVTDGVSHRSALAELDKLEAVLMSVPADRAGRTDQEDSADTEIAARLTAILSRWNKTRTPARPDAGDGTGETDLADATESEVLDFIDRELGRSSVHPTR
>NZ_CP010849.1|WP_078969040.1|840012_842721_-|acyltransferase-domain-containing-protein
MGRELYAAFPVFAAAFDEVFAGLDGHLDGPLREVLFEETPAARPLDRTGWTQPALFAVEVALFRLLGSWGVRPDFVAGHSIGEVAAAYVAGVFGPEDACRVVAARGRLMQRLPSGGSMVAVEASEDDVLPLLAYGVSVAAVNGPSSVVVSGAAGVVEEVVAVLRRRGCRTRRLSVSHAFHSPLMDPVVEEFASVVGAVELAEPVIAMAGGEGVCSARYWAEHVRRPVRFADHVVWLRERGVTRFVEVGPEGVLSALGPQSAPDAVFVALQQREGSQVRGVLTGLARLHTVGHTVDWSRLFTGTGAALVDLPTYPFQHQPYWLAQASSGDVVAAGQTAASHPMLDAVVRVAGADEVVFTGRLTARTHTWITEHELGGRALVPGTALIDMALRAGDETGCAGVSEMVVTAPLVIPGTGGVRIQLVVKEAEDTGHRPFAIHSCRDDEQEWTCHATGTLAPSAPQPRFDLSQWPPPGARPVPTDGFYDRLAEHGYVYGPTFRGLRTLWRRDGSAGAEFFAEVALPDDTDTARFGIHPALFDAAIHPRVVAAIADAGDDFTLLLPFVWNGISLYATGASSLRVRVLIGDESEGGTSCEVQLADDRGRPVAEVRSVEARPVSAAPQETAGSLFAVDWTPVEVGPQGPAGRWALLGTHDPALGEALGADHRETLAEAAGADVLVVHPTAQRDCGVLAAVHDTAAETLELVRAWLADDRFLSSRLLAVTRGAVATGEHGSDPDLAGAAVWGLLRSAQSEHPGRIVLADIDDDPASLAVLPAVPVSGHDQVAVRAGAVLVPRLAPLPASDTAGPEPDPDGTVLVTGGTGALGALFARHLVTHHGVITSYSIHYTKLYDRERGGVVVDGGQHDPAGVLRNNFVKHTLYEVIRPRARRGRRRWRPARSGRGAP
>NZ_CP010849.1|WP_078969041.1|842396_844475_-|hypothetical-protein
MSNEQKLREYLRRVTTDLQRAQRELRDAEAVAREPIAIVGMAGRFPGGAGTPEGLWELVRDGREALTDFPADRGWDLDRLSDPDPATPGTTYLTRGGFLPDAGHFDAEFFGISPREALAMDPQQRLLLEASWEALESARIDPASLRGSSAGVFVGVIPQEYMPRAGETPEELEGFVLTGGTTSVASGRIAYVLGLLGPAVTLDTACSSSLVSVHLAEQSLRSGECDLALAGGATVMAGPSVFVEFSRQRGLARDGRCKAFAAGADGTGFSEGVGVLVLARLSEARRRGLPVLAVIRGSAVNSDGASNGLTAPNGPSQQRVIRQALANAALAPADIDVVEGHGTGTRLGDPIEAQALLATYGQSRPEGRPLLLGSLKSNIGHTQAAAGVAGVIKLVMAMRHGVVPATLHVDEPTPAVDWSAGSVELVTEARPWPETGRPRRAAVSSFGISGTNAHLILEQAPEPTPGPAREPGPGPAPESVPEPAAVPVPVVVSGRSVGALRDVAGRLVSVVEGGVPLGDVGLSSAVSRSVFEHRGVVVAAGREELTAGCGWWRRASRRAKRWRVWREPAAGSLRCSPAREPSGWAWAGSCTRRSRCSRRRSTRCSRGWTGTSTGRCGRCCSRRRRRRGRWTARVGPSRRCSRWRWRCSGCSDRGACGRISWPGTRSVRWRRRTSPGCSVPRTRAGWWRRGAG
>NZ_CP010849.1|WP_052808560.1|850930_852793_-|hypothetical-protein
MDDEKPIALGGDRRRATLGLLLLNANREVATSKLLDGLWDIEETPTTARKILQNAVRGLRVMFAEHTRGDARPPALLTCAHGYQLQVDPEQVDMFRFHRLARTGRAELAAGRPAAAAATLREVLSLWRGRALADLVESGHSWSELTALQNARLDVMEDYYEAELANGRHQAVLGELEAMVAAEPLRERACHQLMLALYRSGRQADALAVYRRVRSRLAEQLGLEPGRELRLLQHAILVHDPSIAAPTGSGRPVVILGRRPEAEHRVRPVPRPVQLVPPAAAGGRSRVSAVLIRADFGGGGRGSDVGEALERTATTVREEVERFGGMVAGSTGSVTLALFRPASPQEDGADRSAERAVHAAMSLRQRISPDLPGGERPALRMAVTTGEISVRPRESFLEPLPVDGALLADCEWLLQLAEDREIVVCDRTRTLTRSAIRYGREGGPRRRWTAQGRCRPAPAEPFDRGPELDVLSSLLERVRHRARPHLVLVLGAPGIGKSPLLAEFERRVENAATVRLGPGRPVTTPDLAGLTEHRPLVVFADDLHLADNAVLELVEDLLDPPAPMPLLVVAAARPELFRRRPGWGAAQRHASRMTLEPVALDPLVEAPEGHELPRLCHAAG
>NZ_CP010849.1|WP_044378988.1|852880_853972_-|HAD-IIIC-family-phosphatase
MSEAQSIVKCLVWDLDNTLWQGTLVEDGHVEVDDAIRKVVMELDARGVLQAVASRNDHDEAWARLEELGLAEYVVLPHIGWGPKSESVRRIAERLNFSLKTIAFIDDLPTERAEVAYHLPDVRCYPAEQAGTLLGLPEFSPPVVTVDARRRRRMYQAGFERDQEREKYQGADEDFLRSLDLEMRIGKARDEEITRVEELTLRTSQMNATGVHYSDAALRSLLSDEDHEVLVVSMTDRFGPHGAVGVMLIEKTPLAWRIKLLATSCRVVSFGAGAVLLRWLTDAAARAGVHLAADFRRTDRNRMMEVAYRFAGFTTARCACLASFSPPESTECLHLEPVRQDPPATMRVIAPEPLVGGPVTRWR

Crispr_ID: NZ_CP010849_4

• CRISPR_ID: NZ_CP010849_4
• CRISPR_location: 1626684-1626889
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP010849_4

Consensus_repeat	Method
GGCGCACGAGGAGGCGCTCGCCGAGGGGCTGGCGGACGGGG	PILER-CR

spacers of NZ_CP010849_4

>4.1|1626725|47|NZ_CP010849|PILER-CR
TCGGCTCGGCCTTCAGGGCGTCGGTGACCGCGCGGCCCTGGGTGGTC
>4.2|1626813|54|NZ_CP010849|PILER-CR
GGCGGACGGCGACGAGCTCGCCTTCTCGCCGTCCGTGGCCTTGTCCGAGGCCGA

CRISPR arrays and Neighbor proteins around NZ_CP010849_4

CRISPR arrays

The CRISPR arrays of NZ_CP010849_4

>merge|NZ_CP010849|4|1626684-1626889|PILER-CR
GGGGGACGAGGAGGCGCTCGCCGAGCCGCTGCCGGACGGGGTCGGCTCGGCCTTCAGGGCGTCGGTGACCGCGCGGCCCTGGGTGGTCGCGCTCGCCGTGGGGCTGGCGGAGGCGGACGGCGACGAGCTCGCCTTCTCGCCGTCCGTGGCCTTGTCCGAGGCCGAGGCGCCCGGGGAGGCGCTCGCCGAGGGGCTGGCCGTCGGGG

>NZ_CP010849|4|1|1626684-1626889|PILER-CR
GGGGGACGAGGAGGCGCTCGCCGAGCCGCTGCCGGACGGGG	TCGGCTCGGCCTTCAGGGCGTCGGTGACCGCGCGGCCCTGGGTGGTC
GCGCTCGCCGTGGGGCTGGCGGAGGCGGACGGCGACGAGCT	CGCCTTCTCGCCGTCCGTGGCCTTGTCCGAGGCCGAGGCGCCCGGGGAGGCGCT
CGCCGAGGGGCTGGCCGTCGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044380129.1|1624358_1625516_-|protein-translocase-subunit-SecF	unknown	unknown	gnl|CDD|237275
NZ_CP010849.1|WP_044380118.1|1615795_1616458_-|vitamin-K-epoxide-reductase-family-protein	unknown	unknown	gnl|CDD|240605
NZ_CP010849.1|WP_044380142.1|1630618_1631371_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|234640
NZ_CP010849.1|WP_044380150.1|1633856_1635020_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP010849.1|WP_044380116.1|1614393_1615752_-|replication-associated-recombination-protein-A	unknown	unknown	gnl|CDD|237355
NZ_CP010849.1|WP_044380114.1|1613445_1614060_-|30S-ribosomal-protein-S4	unknown	unknown	gnl|CDD|235411
NZ_CP010849.1|WP_029383096.1|1632060_1632975_-|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	unknown	unknown	gnl|CDD|179769
NZ_CP010849.1|WP_044380125.1|1619797_1621027_+|DUF349-domain-containing-protein	unknown	unknown	gnl|CDD|377186
NZ_CP010849.1|WP_029383109.1|1617945_1618653_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293792
NZ_CP010849.1|WP_044380134.1|1628157_1629261_-|Holliday-junction-branch-migration-DNA-helicase-RuvB	unknown	unknown	gnl|CDD|234619
NZ_CP010849.1|WP_044380131.1|1627435_1627930_-|preprotein-translocase-subunit-YajC	unknown	unknown	gnl|CDD|376903
NZ_CP010849.1|WP_044380137.1|1629288_1629894_-|Holliday-junction-branch-migration-protein-RuvA	unknown	unknown	gnl|CDD|234645
NZ_CP010849.1|WP_044380152.1|1635016_1635937_-|phosphatidylinositol-mannoside-acyltransferase	unknown	unknown	gnl|CDD|236131
NZ_CP010849.1|WP_044380147.1|1633097_1633640_-|membrane-protein	unknown	unknown	gnl|CDD|224618
NZ_CP010849.1|WP_044380140.1|1629890_1630505_-|crossover-junction-endodeoxyribonuclease-RuvC	unknown	unknown	gnl|CDD|234587
NZ_CP010849.1|WP_044380120.1|1616669_1617932_-|histidine--tRNA-ligase	unknown	unknown	gnl|CDD|234586
NZ_CP010849.1|WP_044380145.1|1631447_1632056_-|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	unknown	unknown	gnl|CDD|237411
NZ_CP010849.1|WP_044380123.1|1618843_1619662_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NZ_CP010849.1|WP_044380127.1|1621113_1623651_-|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl|CDD|223394
NZ_CP010849.1|WP_029383105.1|1623822_1624362_-|adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|235028

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044380129.1|1624358_1625516_-|protein-translocase-subunit-SecF	gnl|CDD|237275	PRK13022, secF, protein translocase subunit SecF.	9.16526e-114
NZ_CP010849.1|WP_044380118.1|1615795_1616458_-|vitamin-K-epoxide-reductase-family-protein	gnl|CDD|240605	cd12922, VKOR_5, Vitamin K epoxide reductase family in bacteria. This family includes vitamin K epoxide reductase (VKOR) mostly present in actinobacteria. VKOR (also named VKORC1) is an integral membrane protein that catalyzes the reduction of vitamin K 2,3-epoxide and vitamin K to vitamin K hydroquinone, an essential co-factor subsequently used in the gamma-carboxylation of glutamic acid residues in blood coagulation enzymes. All homologs of VKOR contain an active site CXXC motif, which is switched between reduced and disulfide-bonded states during the reaction cycle. In some bacterial homologs, the VKOR domain is fused with domains of the thioredoxin family of oxidoreductases which may function as redox partners in initiating the reduction cascade.	1.32663e-57
NZ_CP010849.1|WP_044380142.1|1630618_1631371_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl|CDD|234640	PRK00110, PRK00110, YebC/PmpR family DNA-binding transcriptional regulator.	1.90067e-148
NZ_CP010849.1|WP_044380150.1|1633856_1635020_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	8.56312e-74
NZ_CP010849.1|WP_044380116.1|1614393_1615752_-|replication-associated-recombination-protein-A	gnl|CDD|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP010849.1|WP_044380114.1|1613445_1614060_-|30S-ribosomal-protein-S4	gnl|CDD|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	1.11197e-90
NZ_CP010849.1|WP_029383096.1|1632060_1632975_-|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	gnl|CDD|179769	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS.	0
NZ_CP010849.1|WP_044380125.1|1619797_1621027_+|DUF349-domain-containing-protein	gnl|CDD|377186	pfam03993, DUF349, Domain of Unknown Function (DUF349). This domain is found singly or as up to five tandem repeats in a small set of bacterial proteins. There are two or three alpha-helices, and possibly a beta-strand.	2.73481e-16
NZ_CP010849.1|WP_029383109.1|1617945_1618653_-|MBL-fold-metallo-hydrolase	gnl|CDD|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	1.43442e-65
NZ_CP010849.1|WP_044380134.1|1628157_1629261_-|Holliday-junction-branch-migration-DNA-helicase-RuvB	gnl|CDD|234619	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.	0
NZ_CP010849.1|WP_044380131.1|1627435_1627930_-|preprotein-translocase-subunit-YajC	gnl|CDD|376903	pfam02699, YajC, Preprotein translocase subunit. See.	2.90288e-24
NZ_CP010849.1|WP_044380137.1|1629288_1629894_-|Holliday-junction-branch-migration-protein-RuvA	gnl|CDD|234645	PRK00116, ruvA, Holliday junction branch migration protein RuvA.	2.10332e-74
NZ_CP010849.1|WP_044380152.1|1635016_1635937_-|phosphatidylinositol-mannoside-acyltransferase	gnl|CDD|236131	PRK07920, PRK07920, lipid A biosynthesis lauroyl acyltransferase; Provisional.	1.28339e-155
NZ_CP010849.1|WP_044380147.1|1633097_1633640_-|membrane-protein	gnl|CDD|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	0.000241691
NZ_CP010849.1|WP_044380140.1|1629890_1630505_-|crossover-junction-endodeoxyribonuclease-RuvC	gnl|CDD|234587	PRK00039, ruvC, Holliday junction resolvase; Reviewed.	9.92376e-82
NZ_CP010849.1|WP_044380120.1|1616669_1617932_-|histidine--tRNA-ligase	gnl|CDD|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	0
NZ_CP010849.1|WP_044380145.1|1631447_1632056_-|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	gnl|CDD|237411	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT.	1.52614e-116
NZ_CP010849.1|WP_044380123.1|1618843_1619662_+|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	3.90043e-43
NZ_CP010849.1|WP_044380127.1|1621113_1623651_-|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl|CDD|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_CP010849.1|WP_029383105.1|1623822_1624362_-|adenine-phosphoribosyltransferase	gnl|CDD|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	4.91604e-85

Protein sequences

>NZ_CP010849.1|WP_044380129.1|1624358_1625516_-|protein-translocase-subunit-SecF
MSKLGNLGARLHRGEVGYDFVKNRKIWYGISILITITAIVGLAVRGLNMGIEFQGGAVFTTPKNTAVSVAQAEEHAEEASGHDAIVQKLGDGSLRIQVAGIDTGKSDQIKEDLAEDLKVDAEQINADLVGPSWGDQIANKAWQGLGIFLILVVIYLAIAFEWRMALAAFVALIHDITITVGIYALVGFEVTPGTVIGLLTILGYSLYDTVVVFDSLKEQTRDIGKQTRWTYSDVANRSINSTLVRSVNTTVVALLPVAGLLFIGGGVLGAGMLNDISLSLFVGLAAGAYSSIFIATPLVADLKELEPQMKALKKRVLAKRAQAVAKGEPTEAELAEGGAYAEEAEDIEEAEDAMEPQDAAPAVVGPRNQPASRSRGRGRPSGKRR
>NZ_CP010849.1|WP_029383105.1|1623822_1624362_-|adenine-phosphoribosyltransferase
MTDIRELLLSRIRDVADYPEPGVMFKDITPLLADPGAFTALTDELARIAERHAATKIVGLEARGFILGAPVAVRAGLGFIPVRKAGKLPGATLRQSYDLEYGSAEIEVHAEDLSAGDRVLVVDDVLATGGTAEASLQLIRRAGAEVAGVAVLMELAFLGGRARLEPALEGAPLEALLTV
>NZ_CP010849.1|WP_044380127.1|1621113_1623651_-|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MPDEAQHLTAAKPEPASAPAAKPAPSEPQAKNDTRGPIQHAQSAPVDKPSGQPRPKPAPPERPHNAPVVRTPAGPPARSGSSNRVRARLARLGVQRANPYNPVLEPLLRIVRSNDPKIETSTLRQIERAYQVAERWHRGQKRKSGDPYITHPLAVTTILAELGMDPATLMAGLLHDTVEDTEYGLEDLRRDFGDVVALLVDGVTKLDKVKFGEAAQAETVRKMVVAMAKDPRVLVIKLADRLHNMRTMRYLKREKQEKKARETLEIYAPLAHRLGMNTIKWELEDLAFAILYPKMYDEIVRLVAERAPKRDEYLAIVTDEVQQDLRAARIKATVTGRPKHYYSVYQKMIVRGRDFAEIYDLVGIRVLVDTVRDCYAALGTVHARWNPVPGRFKDYIAMPKFNMYQSLHTTVIGPGGKPVELQIRTFDMHRRAEYGIAAHWKYKQEAVAGASKIRTDAPKSSGKDKDAINDMAWLRQLLDWQKETEDPSEFLESLRFDLSRNEVFVFTPKGDVIALPAGATPVDFAYAVHTEVGHRTIGARVNGRLVPLESTLDNGDLVEVFTSKAPGAGPSRDWLGFVKSPRARNKIRAWFSKERRDEAIEQGKDAIVRAMRKQNLPIQRILTGDSLVTLAHEMRYADISALYAAIGEGHVSAQNIVQKLVQALGGEEAATEEIDESVPPSRGRGRKRRTSADPGVVVKGVEDVWVKLARCCTPVPGDPIIGFVTRGSGVSVHRSDCVNVESLSREPERILDVEWAPTQSSVFLVAIQVEALDRSRLLSDVTRVLSDQHVNILSAAVQTSRDRVATSRFTFEMGDPKHLGHVLKAVRGVEGVYDVYRVTSARRPS
>NZ_CP010849.1|WP_044380125.1|1619797_1621027_+|DUF349-domain-containing-protein
MSSDPWGRVDETGTVYVRTADGEQVVGSWQAGSPDEALAYFERKYEGLVVEIGLLEKRVKTTDLSAKDALAAIEHLREQVDAHHAVGDLDALRARLDKLVELVEARREERKAQRARQTDEARHAKEALVAEAEELAQSDQWRAAGERLRALVDTWKGLPRLDRKSDDELWHRFSHARSAFSKRRKQHFAQLDAQREEARRIKERLVAEAESLSGSTDWGPTAARYRELMAEWKAAGRAQREHEEDLWNRFRGAQDVFFAARSSVFAERDAEQAENLKLKEELAEEAEKLLPVTDLKAARAAFRSINERWEAIGHVPRDARPKVEGRMHAVERAIQEAEEAEWRRTNPEARARAEGLTGQLQAAVDKLQRQIEQARAQGNNAKADKLQKELEGRQALLDQALKGLQEFGG
>NZ_CP010849.1|WP_044380123.1|1618843_1619662_+|peptidylprolyl-isomerase
MVSQEQRRRQLAREKFLRQQQRRTAARRKARARNAVIASVLGVVLVGSVGLYTTGVLKDDGDDKANANAEVSPSATSKAPDPCEKPAEGKAATATWKKEPAMTIDKSAKYTMRLDTTCGAIDIDLKASAAPHTVNSFSFLAGKGYFDHTKCHRLTTNGIYVLQCGDPTGQGTGGPGYTIPDENLKDKSLKDNVYPAGTVAMANTGQKNSGGSQFFLVYQDSPLPPSYTPFGTVSEAGMKVLKKIAGAGESTGAGDGAPNATVVIDKATVTKS
>NZ_CP010849.1|WP_029383109.1|1617945_1618653_-|MBL-fold-metallo-hydrolase
MLIAGFPAGAWGTNCYLVAPAAGEECVIIDPGHQAAQGVEEALKKHRLKPVAVVLTHGHIDHVASVVPVCGAHDVPAWIHPSDRYMMSDPEKALGRSIGMPLMGELTVGEPDDVKELTDGATLELAGFRFSVAHAPGHTKGSVTFGLPEAADIPPILFSGDLLFAGSIGRTDLPGGDMADMLDSLARVCLPLDDSTVVLSGHGPQTTIGQERATNPYLRQVAAGQGAAEAPRRGM
>NZ_CP010849.1|WP_044380120.1|1616669_1617932_-|histidine--tRNA-ligase
MSTFKAPKGTYDLIPPDSAKYLAVREAIAAPLRGSGYGYIETPGFENVELFARGVGESTDIVTKEMYAFETKGGDRLALRPEGTASVLRAALEASLHKAGNLPVKLWYSGSYYRYERPQKGRYRHFSQVGAEAIGAEDPALDAELIILADQAYRSLGLRNFRILLNSLGDKECRPVYREALQAFLRGLDLDEDTLRRAEINPLRVLDDKRPDVQKQLTDAPLLRDYLCDACKAYHEEVRSLITAAGVSFEDDPKLVRGLDYYTRTTFEFVHDGLGSQSAVGGGGRYDGLSEMIGGPALPSVGWALGVDRTVLALEAEGVELELPATTSVFAVPLGEEARRVLFAKVTELRKNGIAADFAYGGKGLKGAMKNANRSGARYAIVAGERDLAEGVVQLKDMESGEQTAVGVNEIVAELESRLG
>NZ_CP010849.1|WP_044380118.1|1615795_1616458_-|vitamin-K-epoxide-reductase-family-protein
MSKTTVKDVSTEPEPSPEGTAGTPRAEGGSRAFGLLLVITGAAGLLAAWVITLDKFKLLEAKVAGKTFTPGCSLNPVVSCGSVMESKQAAAFGFPNPMLGLVAYGIVVCVGMSLLARARFPRWYWLTFNAGTLFGVGFCAWLMFQSLYRINALCLWCCLAWVATIVMFWYVTSFNVRKGFLPAPAWLRGFFGEFTWVLPVLHIGIIGMLILTRWWDFWTS
>NZ_CP010849.1|WP_044380116.1|1614393_1615752_-|replication-associated-recombination-protein-A
MEPDLFTAAAEERQEKEPSSSPLAVRMRPRTLDEVVGQQHLLKPGSPLRRLVGEGTSGSPAGPSSVILWGPPGTGKTTLAYVVSKATNKRFVELSAITAGVKEVRAVIDGARRASGGYGKETLLFLDEIHRFSKAQQDSLLPAVENRWVTLIAATTENPYFSVISPLLSRSLLLTLEPLTDDDIRDLLRRALADERGLGGAVALPEDTEDHLLRIAGGDARRALTALEAAAGAALDKGETEIGLTTLEETVDRAAVKYDRDGDQHYDVASALIKSIRGSDVDAALHYLARMIEAGEDPRFIARRLMISASEDIGLADPNALPIAVAAAQAVAMIGFPEAALTLSHATIALALAPKSNAATTAIGAALDDVRKGLAGPVPPHLRDSHYKGAGKLGHGQGYVYPHDLPEGIAAQQYAPDALKDREYYTPTRHGAEARYADAVEWTRKHLGRRRS
>NZ_CP010849.1|WP_044380114.1|1613445_1614060_-|30S-ribosomal-protein-S4
MANQSRPKVKKSRALGIALTPKAVKYFEARPYPPGEHGRGRKQNSDYKVRLLEKQRLRAQYDISERQLVRAYERASKVQGKTGEALIVELEKRLDALVLRSGIARTIYQARQMVVHGHIQVNGKKVDKPSFVVRPDDVVQVRERSKEKTLFTIAREGGFAPDGETPRYLQVNLKALAFRLDREPNRKEIPVICDEQLVVEYYAR
>NZ_CP010849.1|WP_044380131.1|1627435_1627930_-|preprotein-translocase-subunit-YajC
MSLVTLLPFIVLIGAMFLMTRSAKKKQQQALDMRNQMQPGSGVRTIGGMYATVKEVNEDTVLLDAAPGVELVFAKNSIGAVLSDDEYNRIVHGIEHDLKNDADIVPDDASSLTESDDSAAGAPDDKPVDLGKKDQADEPADEPVAAEAKTDEEPKKTDGDTETK
>NZ_CP010849.1|WP_044380134.1|1628157_1629261_-|Holliday-junction-branch-migration-DNA-helicase-RuvB
MNWDDTTDSAAGQPAGPAGERLVGPVADGEDQAVEAALRPKDLDEFIGQEKVREQLDLVLRAARARGATADHVLLSGAPGLGKTTLSMIIAAEMGAPIRITSGPAIQHAGDLAAILSSLQEGEVLFLDEIHRMSRPAEEMLYMAMEDFRVDVIVGKGPGATAIPLELPPFTLVGATTRAGLLPPPLRDRFGFTAHMEFYEPAELERVVHRSASLLDVEIEPDGAAEIAGRSRGTPRIANRLLRRVRDYAQVKADGVITKEIAEAALAVYEVDARGLDRLDRAVLHALLKLFGGGPVGLSTLAVAVGEERETVEEVAEPFLVREGLLARTPRGRIATPAAWAHLGLTPPLQQTGGKTGGNGQGDLFGT
>NZ_CP010849.1|WP_044380137.1|1629288_1629894_-|Holliday-junction-branch-migration-protein-RuvA
MIAFVSGTVAALAPDTAVIEVGGVGMALQCTPNTLSTLRVGRSAKLATSLVVREDSLTLYGFADDDERQVFELLQTASGVGPRLAQAMLAVHTPDALRRAVSTADEKALTAVPGIGKKGAQKLLLELKDRLGEPVGAPAATTPAASGWRDQLHAALIGLGYATREADEAVAAVAPQAEAAGGTPQVGRLLKAALQTLNRAR
>NZ_CP010849.1|WP_044380140.1|1629890_1630505_-|crossover-junction-endodeoxyribonuclease-RuvC
MRVLGVDPGLTRCGVGVVEGVAGRPLTMLGVGVVRTPADAELGHRLVAIEQGIEDWLDEHRPEYVAVERVFSQHNVRTVMGTAQASAVALLCASRRGIPVALHTPSEVKAAVTGSGRADKAQVGAMVTRLLRLAAPPRPADAADALALAICHIWRAPAQNRLQQAVARHQGTAARSSPAPRASRAPGTPAAPSAVPHASKGRTA
>NZ_CP010849.1|WP_044380142.1|1630618_1631371_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MSGHSKWATTKHKKAVIDAKRGKLFAKLIKNIEVAARMGGADPDGNPTLYDAIQKAKKSSVPNKNIDSAVKRGAGLEAGGADYETIMYEGYGPNGVAVLIECLTDNRNRAASEVRVAMTRNGGSMADPGSVSYLFNRKGVVIVPKGELTEDDVLTAVLDAGAEEVNDLGETFEVISEPTDLVAVRTALQNAGIDYESADANFVPTMQVELDEEGAKKIFKLIDALEDSDDVQNVFANFDVSDEIMEKVDA
>NZ_CP010849.1|WP_044380145.1|1631447_1632056_-|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT
MSEAPVIGVLALQGDVREHLIALAAADAVARPVRRPGELAEVDGLVLPGGESTTISKLAVLFGVMEPLRARVRAGMPVYGTCAGMILLADKILDPRAGQETVGGIDMIVRRNAFGRQNESFEAAVDVKGVEGDPVEGVFIRAPWVESVGAGAEVLAEHDGHIVAVRQGNALATSFHPELTGDHRVHRLFTDMVRADRAAESL
>NZ_CP010849.1|WP_029383096.1|1632060_1632975_-|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS
MSTTTPNSAQTPETGTARVKRGMAEQLKGGVIMDVVTPEQAKIAEDAGAVAVMALERVPADIRKDGGVARMSDPDMIEGIIDAVSIPVMAKSRIGHFVEAQVLQSLGVDYIDESEVLTPADEVNHSDKWAFTTPFVCGATNLGEALRRIAEGAAMIRSKGEAGTGNVVEAVRHLRQIKNEIARLRGYDNNELYAAAKELRAPYELVKEVAELGKLPVVLFSAGGVATPADAALMRQLGAEGVFVGSGIFKSGDPAKRAAAIVKATTFYDDPKIIADASRNLGEAMVGINCDTLPETERYANRGW
>NZ_CP010849.1|WP_044380147.1|1633097_1633640_-|membrane-protein
MTATLIWILVVLVAIGLYLSWTAGRLDRLHARIDAARAALDAQLLRRASVAQELATSGVLDPAASIVLYEAAHAARQAEEEQREVAESELSQALRAVFADSRQVEGLREAPGGEEAARELAEAVRRVPMARRFHNDAVGAARRLREHRKVRWFRLAGHAPFPLAFEMDDEPPAALVERVA
>NZ_CP010849.1|WP_044380150.1|1633856_1635020_-|glycosyltransferase-family-4-protein
MRIGIVCPYSWDVPGGVQFHIRDLAEYFIRLGHEVSVLAPADDDTPLPPYVVSAGRAVPVPYNGSVARLNFGFLSAARVRRWLHEGAFDVIHIHEPTSPSLGLLACWAAQGPIVATFHTSNPRSRAMIAAYAILQAALEKISARIAVSEYARRTLVEHLGGDAVVIPNGVDVDFFAGAGPRPEWQGDTIGFIGRIDEPRKGLPVLMRALPKILAARPETRLLVAGRGDEEEAVASLPKELRPRVEFLGMISDEDKARLLRSVDLYVAPNTGGESFGIILVEAMSAGAPVLASDLDAFAQVLDRGAAGELFPNEDADALAEAAVRLLADPARRAELRARGSAHVRRFDWSTVGADIMSVYETVTAGAAAVATDDRATGLRARLGLARD
>NZ_CP010849.1|WP_044380152.1|1635016_1635937_-|phosphatidylinositol-mannoside-acyltransferase
MNPRDRLSDALYGLGWSTVKQLPEPVAVRLGRTIADLAWKQRGTGVRRLESNYARVVPGASPERLAELSRAGMRSYLRYWMESFRLPAWSAERIRGAFAGEDMHHLTDAMAEGRGAVLALPHLANWDLAGAWLTTELGLPFTTVAERLKPESLYDRFVAFREGLGMEVLPHTGGTAFGALARRLRGGGLVCLVADRDLSASGVEVTFFGETARMPAGPALLAQQTGAALLPVTLWYDDSPVMRGRVHPPVEVPGTGTRREKAAVMTQALADAFATGISAHPEDWHMLQRLWLADLDPAKAPEEGAS

Crispr_ID: NZ_CP010849_6

• CRISPR_ID: NZ_CP010849_6
• CRISPR_location: 1670633-1670744
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_6

Consensus_repeat	Method
CCGGAACCGGGGCGGGCTCGGAGACCTG	CRISPRCasFinder

spacers of NZ_CP010849_6

>6.1|1670661|56|NZ_CP010849|CRISPRCasFinder
GACCGCCTCCATGACCCCGGGCGCTTCCACGGCCGGGGCCACGGCCTCGGCGGATT

CRISPR arrays and Neighbor proteins around NZ_CP010849_6

CRISPR arrays

The CRISPR arrays of NZ_CP010849_6

>merge|NZ_CP010849|6|1670633-1670744|CRISPRCasFinder
CCGGCACCTGGGGCGCTTCCGGGACCTGGACCGCCTCCATGACCCCGGGCGCTTCCACGGCCGGGGCCACGGCCTCGGCGGATTCCTGCGCCGGGGCGGCATCGGCGGCCTC

>NZ_CP010849|6|5|1670633-1670744|CRISPRCasFinder
CCGGCACCTGGGGCGCTTCCGGGACCTG	GACCGCCTCCATGACCCCGGGCGCTTCCACGGCCGGGGCCACGGCCTCGGCGGATT
CCTGCGCCGGGGCGGCATCGGCGGCCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044380199.1|1659982_1661026_-|chloride-transporter	unknown	unknown	gnl|CDD|130883
NZ_CP010849.1|WP_044380227.1|1678306_1678666_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044380215.1|1672686_1673922_-|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE	unknown	unknown	gnl|CDD|381171
NZ_CP010849.1|WP_044380229.1|1678667_1679102_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_078969090.1|1657560_1658121_+|DsbA-family-protein	unknown	unknown	gnl|CDD|376526
NZ_CP010849.1|WP_044380218.1|1674046_1674682_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP010849.1|WP_044380206.1|1664122_1665580_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP010849.1|WP_078969091.1|1661719_1662004_-|zf-TFIIB-domain-containing-protein	unknown	unknown	gnl|CDD|379195
NZ_CP010849.1|WP_044380235.1|1680253_1681420_-|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176544
NZ_CP010849.1|WP_044380220.1|1674853_1675681_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270315
NZ_CP010849.1|WP_078969092.1|1662084_1663221_-|aminoglycoside-phosphotransferase-family-protein	unknown	unknown	gnl|CDD|366736
NZ_CP010849.1|WP_044380211.1|1666591_1667824_-|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|381169
NZ_CP010849.1|WP_044380233.1|1679683_1680178_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP010849.1|WP_044380231.1|1679128_1679626_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP010849.1|WP_044380194.1|1658287_1659112_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP010849.1|WP_044380196.1|1659164_1659986_-|aminodeoxychorismate-lyase	unknown	unknown	gnl|CDD|238800
NZ_CP010849.1|WP_029387714.1|1663269_1663479_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044380225.1|1676495_1677605_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|236863
NZ_CP010849.1|WP_044380209.1|1665644_1666463_-|RNA-methyltransferase	unknown	unknown	gnl|CDD|223640
NZ_CP010849.1|WP_044380222.1|1675761_1676499_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224922

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044380199.1|1659982_1661026_-|chloride-transporter	gnl|CDD|130883	TIGR01824, Anthranilate_synthase_component_I-like_protein, aminodeoxychorismate synthase, component I, clade 2. This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.	1.54304e-121
NZ_CP010849.1|WP_044380215.1|1672686_1673922_-|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE	gnl|CDD|381171	cd11644, Precorrin-6Y-MT, Precorrin-6Y methyltransferase (also named CbiE). CbiE (precorrin-6Y methyltransferase, also known as cobalt-precorrin-7 C(5)-methyltransferase, also known as cobalt-precorrin-6Y C(5)-methyltransferase) catalyzes the methylation of C-5 in cobalt-precorrin-7 to form cobalt-precorrin-8. It participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways in bacteria. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. CbiE functions in the anaerobic pathway, it is a subunit of precorrin-6Y C5,15-methyltransferase, a bifunctional enzyme: cobalt-precorrin-7 C(5)-methyltransferase (CbiE)/cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) (CbiT), that catalyzes two methylations (at C-5 and C-15) in precorrin-6Y, as well as the decarboxylation of the acetate side chain located in ring C, in order to generate precorrin-8X. CbiE and CbiT can be found fused (CbiET, also called CobL), or on separate protein chains (CbiE and CbiT). In the aerobic pathway, a single enzyme called CobL catalyzes the methylations at C-5 and C-15, and the decarboxylation of the C-12 acetate side chain of precorrin-6B.	5.37072e-46
NZ_CP010849.1|WP_044380233.1|1679683_1680178_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	1.28097e-12
NZ_CP010849.1|WP_078969090.1|1657560_1658121_+|DsbA-family-protein	gnl|CDD|376526	pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyze one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways. This family also contains members with functions other than HCCA isomerisation, such as Kappa family GSTs, whose similarity to HCCA isomerases was not previously recognized. Some members have been annotated as dioxygenases, dehydrogenases, or putative glycerol-3-phosphate transfer proteins, but are most likely HCCA isomerase enzymes.	3.35201e-25
NZ_CP010849.1|WP_044380206.1|1664122_1665580_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.03784e-87
NZ_CP010849.1|WP_078969091.1|1661719_1662004_-|zf-TFIIB-domain-containing-protein	gnl|CDD|379195	pfam13453, zf-TFIIB, Transcription factor zinc-finger.	9.3644e-17
NZ_CP010849.1|WP_044380220.1|1674853_1675681_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270315	cd13597, PBP2_lipoprotein_Tp32, The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum binds L-methionine; the type 2 periplasmic-binding protein fold. This group includes the lipoprotein Tp32, a periplasmic component of a methionine uptake transporter system, and its closely related homologs. The Tp32 has both structural and sequential homology to the MetQ family of substrate-binding protein, and thus it belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	3.53151e-126
NZ_CP010849.1|WP_078969092.1|1662084_1663221_-|aminoglycoside-phosphotransferase-family-protein	gnl|CDD|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	1.49059e-08
NZ_CP010849.1|WP_044380211.1|1666591_1667824_-|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	6.64343e-108
NZ_CP010849.1|WP_044380235.1|1680253_1681420_-|glycerophosphodiester-phosphodiesterase	gnl|CDD|176544	cd08602, GDPD_ScGlpQ1_like, Glycerophosphodiester phosphodiesterase domain of Streptomycin coelicolor (GlpQ1) and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in a group of putative bacterial and eukaryotic glycerophosphodiester phosphodiesterases (GP-GDE, EC 3.1.4.46) similar to Escherichia coli periplasmic phosphodiesterase GlpQ, as well as plant glycerophosphodiester phosphodiesterases (GP-PDEs), all of which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols. The prototypes of this family include putative secreted phosphodiesterase encoded by gene glpQ1 (SCO1565) from the pho regulon in Streptomyces coelicolor genome, and in plants, two distinct Arabidopsis thaliana genes, AT5G08030 and AT1G74210, coding putative GP-PDEs from the cell walls and vacuoles, respectively.	1.4773e-168
NZ_CP010849.1|WP_044380231.1|1679128_1679626_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.94411e-13
NZ_CP010849.1|WP_044380194.1|1658287_1659112_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.66263e-10
NZ_CP010849.1|WP_044380196.1|1659164_1659986_-|aminodeoxychorismate-lyase	gnl|CDD|238800	cd01559, ADCL_like, ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.	8.58413e-85
NZ_CP010849.1|WP_044380218.1|1674046_1674682_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.27539e-30
NZ_CP010849.1|WP_044380225.1|1676495_1677605_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|236863	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional.	5.22975e-169
NZ_CP010849.1|WP_044380209.1|1665644_1666463_-|RNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	1.25285e-60
NZ_CP010849.1|WP_044380222.1|1675761_1676499_-|ABC-transporter-permease	gnl|CDD|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	4.95306e-99

Protein sequences

>NZ_CP010849.1|WP_044380211.1|1666591_1667824_-|uroporphyrinogen-III-C-methyltransferase
MAEHPAYPVGLRLTGRRVVVLGGGQVAQRRLPALIAAGADIVLVSPEATPSVEAMADAGEITWRKRRYEDGDLADAWYALIATSDRPANEAASAEAERNRVWCVRSDDADAATAWTPATGHSEGVTVAVLTTDARGRDPRHTAAVRDAVVEGLRDGTLVAPHHRTRVPGVALVGGGPGDPDLITVRGRRLLAEADVVIADRLGPRDLLAELPPHVEVIDAAKIPYGRFMAQEAINNALIEHAKQGKSVVRLKGGDPFVFGRGMEEAQALAEAGIPCTVVPGISSSISVPGAAGIPVTHRGVAHEFTVVSGHVAPDDERSLVDWPSLAKLTGTLVILMGVDKIGRIAETLVAHGKAPDTPVALVQEGTTAAQRRVDATLATVAETVRAQEVKPPAVIVVGEVVHVGPRQTA
>NZ_CP010849.1|WP_044380209.1|1665644_1666463_-|RNA-methyltransferase
MAELITVEDPADPRLGDYTDLTDVELRRRREPAEGLFIAEGEKVIRRARDAGYAMRSMLLSAKWVDAMRDVIDASPAPVYVVDPRLAERVTGYHVHRGALASMQRRPLPEAAELVATARRVVVMESVNDHTNIGAIFRSAAALGMDAVLLSPDCADPLYRRSVKVSMGAVFSVPYARLDPWPRSLGTLREAGFTLLALTPDEKATALDEAAPHRMDRVALMLGAEGEGLSRRALAAADEWVRIPMSHGVDSLNVGAAAAVAFYAVATGRPGT
>NZ_CP010849.1|WP_044380206.1|1664122_1665580_+|serine/threonine-protein-kinase
MNMAMMRLRREDPRVVGSFRLHRRLGAGGMGVVYLGSDKKGQRVALKVIRPDLAEDQEFRSRFAREVSAARRIRGGCTARLVAADLEADRPWFATQYVPGPSLHDKVVDEGPLCAADVAAVGAALSEGLVAVHEAGVVHRDLKPSNILLSPKGPRIIDFGIAWATGASTLTHVGTAVGSPGFLAPEQVRGAAVTPATDVFSLGATLAYASMGDSPFGHGSSEVMLYRVVHEEPQLHGVPDALAPLIRACLAKDPEERPSTLQLSLRLKEIAAREAQGLADVRPPAPRAGETDRPTGRLGDSYPERTQRRPQERSGAPGTPVPRGASGARGGTPPRGTASPRGGSASRGGTGSRSERPGSRPRPTPASRNATGRNTGRNTGRNTTRSGGGRPGPRTGGGRPAPRGTGTGLRPANPRLLRQRLFVFVVVTLLVALGIAAAQGCQGPARGLGGDRQDVRQQQELVRPGHTPGEAGTPHAAEPAPGRTG
>NZ_CP010849.1|WP_029387714.1|1663269_1663479_-|hypothetical-protein
MAHTAPRTLIREEGRKAYAAAFRPRRQGRRHPLVATVMALPLAVLLLLVFDGWETVATQASSVGAMLGR
>NZ_CP010849.1|WP_078969092.1|1662084_1663221_-|aminoglycoside-phosphotransferase-family-protein
MKPRGDGGAADGTDAGAAGELRRHCPFPRPARAGAPCRSAAGRRPAARPPPRRGPPANAPYPHPVTTPPPLLPALAERATAAAHARAPGCACGATVTLADRPDATVVRHAATVAKAHAPDTDPDALAARLGAAARLPGILLPPLRPAPVRLRGRHVTFWPYGTPVDPDDPDAAPWEAAATLLARLHRSSLPGLRLPPMRGPVKAAHAVARLRAAAAHPGAVPVLRAWAGLPAWARGEAPPPKTAVVCHGDLHLGQLVRHPAPDGPWLLIDVDDLGVGVPAWDLARPAAWYACGVLPPEQWARFLAAYRSASGPAVPQDGDPWPALDVPARALTVQTAARAVTKAAAEERPLDEVERALVDACARMAALPADPAASGAT
>NZ_CP010849.1|WP_078969091.1|1661719_1662004_-|zf-TFIIB-domain-containing-protein
MQCPKCHGPMHTYNRNGVQIEQCSSCRGIFLDYGELEALTRLESQWAQPAPPPPPAPHAYPAPPVPPAAPAWGAPHGGHGHHRQRSFGRMLFSS
>NZ_CP010849.1|WP_044380199.1|1659982_1661026_-|chloride-transporter
MLELPPLARFGDRVATGLLDVTSDPAALDSSGFWAVCADFEGRLTCARFRDVRREPVPAPVPGGWRGPAVGDWTSSLDRSAYTAAVRRIRAHIAAGEVYQANLCRVLSAPVAPDADVDALTAVLARGNPAPYAGTIRLPEHGVETATASPELFLRRDGRIVESGPIKGTGRTEADLLEKDYAENVMIVDLVRNDIGRVCATGSVTVPDLCVVEKHPGLVHLVSTVRGELRTGAGWPELLDAAFPPGSVTGAPKESALRIIEALETAPRGPYCGGIGWVDADRGTGELAVGIRTFWIDRDEGLLRFGTGAGITWGSDPEGEWRETELKASRLLAVASGAYEVSEGTLR
>NZ_CP010849.1|WP_044380196.1|1659164_1659986_-|aminodeoxychorismate-lyase
MKIWLDGGLQDIESARVSVFDHGLTVGDGIFETVKAVDGRPFALTRHLDRLTRSARGLGLPAPDLDEVRRACAAVLEANPMPLGRLRITYTGGHGPLGSDRGDQGPTLVVALGETARRPDSTAVITVPWTRNERSALAGLKTTSYAENVVALARAHAHGASEALFGNTVGRLCEGTGSNVFVVLDGEIHTPPLASGCLAGITRALAVEWTGARETDLPLEVLERADEIFLTSTLRDIQAVHRVDDRELPGVPGPVTAKAMRVFEERSGDDLDP
>NZ_CP010849.1|WP_044380194.1|1658287_1659112_-|GNAT-family-N-acetyltransferase
MTTTLRPTEPLQRAADGTRSRRFQVCVNSRPVGAIHLGTSPSLGDSVARILDLRIDEPDRRRGRATVAVLAAEEVARSWGCRQVEALVPVTAEAALRLARALGYVPRNRAMSKRLGATPPDLPAGSSARPMTPAEFDAWQAHESERYARTWTERGLAEAAARAKARRDHETLLPRGLGTGDMLFSVLEHDGARVGTLWLALREDRAFVFDVETDAAHRGRGHGRSLMLLAEAQSIAAGRDVLGLNVFAGNTPAERLYESLGYETTQYSYCKTLL
>NZ_CP010849.1|WP_078969090.1|1657560_1658121_+|DsbA-family-protein
MGRRRGDWETGSMSDTSPDRPAAPVLDVWCELQCPDCRTALDDLGALRARYGDRLELRLRHFPLEKHKHAFAAAQAAEEAVAQGKGWEYVEAVLARVEELDRKGEPFLVEAARELGLDAEEFDTALIDGRHILIVDADQAEGKAIGVTGTPTYVIGGERLDGGKSQEGLRERIEEIADRLLGARES
>NZ_CP010849.1|WP_044380215.1|1672686_1673922_-|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE
MADRVTVIGWDGSPLTAAARAALGAATLVAGAAHHLALPEVPPAAERIRLGSVALAARRIAAHRGTAVVLADGDPGFFGVVRTLRAPEFGLEVEVVPAVSSVATAFARAGMPWDDAQVVVAHPRTLRRAVNVCRAHTKVAVLTAPGAGPAELGLLLDEVHRTFVICEELGTTHERVTVVTSDKAADHTWRDPNVVIVIGGPSGPGVAADGGGWIAGRDPAAGPRGWSLPAGAYGGDLGEGETDLLRTAQLARLGPRLGDLVWDIGCGSGAFATEAARGGAAVIAVDRDPDACARTEATARRFGVQLQTVCGTAPHVLEDLPEPDVVRVGGGGAAVVSAVADRRPQRIVTHAATRDAAELVGRDLTEHGYVVECALLQSVALDTRAWTEKERSVAFLLSGELPRREGGAPGR
>NZ_CP010849.1|WP_044380218.1|1674046_1674682_-|GNAT-family-N-acetyltransferase
MTSTFPGISISTERLVLRPLETDDVPALAAMMNDEQVGAWTDVPQPFTEDGARDWITERAPARRAAGRGLDLAVTEFLTQRLVGVIRLTRTNWRVRSTELSYIIAPWARGEGYASEAALATARWLFGDQKFERIELRTAADNTASQQVAQKIGCISEGVLRNACIAHVRAEDGTWTDVRTDFIVWSLLPEDLEGAGGHPADTGFTTFTDWN
>NZ_CP010849.1|WP_044380220.1|1674853_1675681_-|ABC-transporter-substrate-binding-protein
MRNTAKITTAVLAASALTLGLTACGSDKDSASDTSGPLVVAATPVPHAEILTYVKDNLAKKEGLDLEVKEFTDYVTPNTATEDGSVGANYFQTEPYLADFNKKNGTHLKSVASVHLEPLGLYSEKADKPGDLKNGATIAVPNDTVTEARALQLLAANGLLTLKDGVGTEATPADIVKNPKNLKFKELEAAQTPRSLGDVDAAVINGNYALEADLKPAEDALVLESAENNPNVNLLVVKEGNEDDPRVRKLAKLLTSPEVKKFIEDKYAGSVVASF
>NZ_CP010849.1|WP_044380222.1|1675761_1676499_-|ABC-transporter-permease
MTWAEMQPLLEQACRETLVMVGWSTLIAVVAGLPIGVLLVLTDKGGLLQNTLVNKVVGQIVNIGRSLPFIILMVALMNFTRWVTGTTIGSEAAIVPLAIGGIPFFARLVETAVREVDNGLVEAVQAMGGNTWTIVRKVLVPEALPSLIASTTTTIIALIGYSAMAGTVGGGGLGDLAVRYGYQRFETGLMWITVAVLAVVISVIQFAGDYAARSLHRRGGRSGPAPKLRLLKAKEPAAADIEKVA
>NZ_CP010849.1|WP_044380225.1|1676495_1677605_-|ATP-binding-cassette-domain-containing-protein
MITTTGLTKVYRSRGREVTALDGVDLHVREGEVYGVIGQSGAGKSSLIRCINLLERPTSGTVTVAGQDLTALAGRGPRAGRELRQARSRIGMVFQHFNLLSSRTVQDNVELPLEILGKSGKERSRKALELLDLVGLADKAKSYPAQLSGGQKQRVGIARALAGDPKVLLSDEATSALDPETTRSILQLLRDLNRQLGLTVLLITHEMDVVKSICDSAALMERGRIVESGTVGELLATPGSELAAALFPVGGEASADDRTVLDVTFHGEAATQPVISQLSRTYNIDISILGAAIDTVGGLQIGRMRIELPGRYEDNVVPVGFLREQGLQVDVVDVVDATDAADAARAGVTGDAGDTVDDKQSALVKEGAE
>NZ_CP010849.1|WP_044380227.1|1678306_1678666_+|hypothetical-protein
MLDVLMPATGVAALLLAAWCGWAAYRDQPTKDWHFIGMAVVTLLALVQLVVGVVRLAQGEKPDQGTVIFVAYLLGAFACVPAAGFMSLAERTRWGSVTVAAGGVVLAVLEVRLYDIWGG
>NZ_CP010849.1|WP_044380229.1|1678667_1679102_+|hypothetical-protein
MTAAQESASRTRLVGGPGMLLVWLYGVMVVGAVSRSAYQIATEFDRAPLAYSLSAVAGLVYGFITYSLVRGGETARKAALVCCAAELVGVLTVGTWTLIEPSAFPDATVWSDYGMGYVFIPVLLPLSALYWLRKAARAQRPDAG
>NZ_CP010849.1|WP_044380231.1|1679128_1679626_-|GNAT-family-N-acetyltransferase
MGMSVTISAATEQDAEQIFRLQYLCFQDEAALYGNYRIDPLVQTLDSVREEVARDCVFVARLGDEVVGSVRGRVTEDGAASIGRLCVHPRLQGHGIGARLLRAAESALAGERGATRFRLHTGHRGEGNLRLYRRVGYETVGTARGADGVPMVVLEKHAEEYATTA
>NZ_CP010849.1|WP_044380233.1|1679683_1680178_-|sigma-70-family-RNA-polymerase-sigma-factor
MTHELVTNLRPLLTAEVAAEAYASGAEPGDLEQAVWLRLLERLQTDGPPQDVHDWLRSAVRSEGRRTRRALRLERPYPAEPVDDTARDPETLALAAARHRAVREAVRRLPGRCPRLMEALLSPKDLTYREIAGELGISQGSLGPERSRCLGCLRRLLAPEVAAR
>NZ_CP010849.1|WP_044380235.1|1680253_1681420_-|glycerophosphodiester-phosphodiesterase
MGTRESNEQAGGAGRRALLGAAVLGAGGAVLGLPGGTASAAGTRPGGGLRSLPVPTVIGHRGASGYRPEHTLGAYQLALDMGADIVEAGDLVPTRDGHLVCRHEPEIGGTTDVADHPEFAGRKRTKSLDGVVTTGWFTEDFTLAELKTLRATERIPVNRPHNTLYDGRWEIPTFEEVLRWQDEQTRRRGKQVWIYPELKHPTYFRKLGLGLEERVARILRRHGKDGKNSPVILQSFEPTSIQRLDKLVGNPLVVLLSGAGSRPWDFVETGDDRTVADLVTPEGLREIASYAQGIGPTLDLIIPRDPAGRLKEPTTLVSDAHRAGLILHPYTLRNENPFLPADFRRGTDADAYGDVFGAYRAYFATGIDGIFTDHPDTGLLAREEFVNR

Crispr_ID: NZ_CP010849_5

• CRISPR_ID: NZ_CP010849_5
• CRISPR_location: 1670366-1670559
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP010849_5

Consensus_repeat	Method
CCGGAACCGGGGCGGGCTCGGAGACCTG	CRISPRCasFinder

spacers of NZ_CP010849_5

>5.1|1670394|53|NZ_CP010849|CRISPRCasFinder
GGGGCCGGGGACGGGCACGTCGGACGGCGGGGCGTCCTCAGGCACGACTTCCT
>5.2|1670475|56|NZ_CP010849|CRISPRCasFinder
CGGAACCGGGGCGGGCTCGGAGACCTGAGCGACACCCTCCGCGGGCCCGGCGGGCC

CRISPR arrays and Neighbor proteins around NZ_CP010849_5

CRISPR arrays

The CRISPR arrays of NZ_CP010849_5

>merge|NZ_CP010849|5|1670366-1670559|CRISPRCasFinder
CCGCGACCGGCGCGGGCTCGGCACCCTCGGGGCCGGGGACGGGCACGTCGGACGGCGGGGCGTCCTCAGGCACGACTTCCTGGGGGGCCGGAGCGGGCTCGCCGGCCTCCGGAACCGGGGCGGGCTCGGAGACCTGAGCGACACCCTCCGCGGGCCCGGCGGGCCCCGGAACCGGGGCGGCCTCGGAGACCTGG

>NZ_CP010849|5|4|1670366-1670559|CRISPRCasFinder
CCGCGACCGGCGCGGGCTCGGCACCCTC	GGGGCCGGGGACGGGCACGTCGGACGGCGGGGCGTCCTCAGGCACGACTTCCT
GGGGGGCCGGAGCGGGCTCGCCGGCCTC	CGGAACCGGGGCGGGCTCGGAGACCTGAGCGACACCCTCCGCGGGCCCGGCGGGCC
CCGGAACCGGGGCGGCCTCGGAGACCTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044380199.1|1659982_1661026_-|chloride-transporter	unknown	unknown	gnl|CDD|130883
NZ_CP010849.1|WP_044380227.1|1678306_1678666_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044380215.1|1672686_1673922_-|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE	unknown	unknown	gnl|CDD|381171
NZ_CP010849.1|WP_044380229.1|1678667_1679102_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_078969090.1|1657560_1658121_+|DsbA-family-protein	unknown	unknown	gnl|CDD|376526
NZ_CP010849.1|WP_044380218.1|1674046_1674682_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP010849.1|WP_044380206.1|1664122_1665580_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP010849.1|WP_078969091.1|1661719_1662004_-|zf-TFIIB-domain-containing-protein	unknown	unknown	gnl|CDD|379195
NZ_CP010849.1|WP_044380235.1|1680253_1681420_-|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176544
NZ_CP010849.1|WP_044380220.1|1674853_1675681_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270315
NZ_CP010849.1|WP_078969092.1|1662084_1663221_-|aminoglycoside-phosphotransferase-family-protein	unknown	unknown	gnl|CDD|366736
NZ_CP010849.1|WP_044380211.1|1666591_1667824_-|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|381169
NZ_CP010849.1|WP_044380233.1|1679683_1680178_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP010849.1|WP_044380231.1|1679128_1679626_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP010849.1|WP_044380194.1|1658287_1659112_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP010849.1|WP_044380196.1|1659164_1659986_-|aminodeoxychorismate-lyase	unknown	unknown	gnl|CDD|238800
NZ_CP010849.1|WP_029387714.1|1663269_1663479_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044380225.1|1676495_1677605_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|236863
NZ_CP010849.1|WP_044380209.1|1665644_1666463_-|RNA-methyltransferase	unknown	unknown	gnl|CDD|223640
NZ_CP010849.1|WP_044380222.1|1675761_1676499_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224922

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044380199.1|1659982_1661026_-|chloride-transporter	gnl|CDD|130883	TIGR01824, Anthranilate_synthase_component_I-like_protein, aminodeoxychorismate synthase, component I, clade 2. This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.	1.54304e-121
NZ_CP010849.1|WP_044380215.1|1672686_1673922_-|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE	gnl|CDD|381171	cd11644, Precorrin-6Y-MT, Precorrin-6Y methyltransferase (also named CbiE). CbiE (precorrin-6Y methyltransferase, also known as cobalt-precorrin-7 C(5)-methyltransferase, also known as cobalt-precorrin-6Y C(5)-methyltransferase) catalyzes the methylation of C-5 in cobalt-precorrin-7 to form cobalt-precorrin-8. It participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways in bacteria. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. CbiE functions in the anaerobic pathway, it is a subunit of precorrin-6Y C5,15-methyltransferase, a bifunctional enzyme: cobalt-precorrin-7 C(5)-methyltransferase (CbiE)/cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) (CbiT), that catalyzes two methylations (at C-5 and C-15) in precorrin-6Y, as well as the decarboxylation of the acetate side chain located in ring C, in order to generate precorrin-8X. CbiE and CbiT can be found fused (CbiET, also called CobL), or on separate protein chains (CbiE and CbiT). In the aerobic pathway, a single enzyme called CobL catalyzes the methylations at C-5 and C-15, and the decarboxylation of the C-12 acetate side chain of precorrin-6B.	5.37072e-46
NZ_CP010849.1|WP_044380233.1|1679683_1680178_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	1.28097e-12
NZ_CP010849.1|WP_078969090.1|1657560_1658121_+|DsbA-family-protein	gnl|CDD|376526	pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyze one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways. This family also contains members with functions other than HCCA isomerisation, such as Kappa family GSTs, whose similarity to HCCA isomerases was not previously recognized. Some members have been annotated as dioxygenases, dehydrogenases, or putative glycerol-3-phosphate transfer proteins, but are most likely HCCA isomerase enzymes.	3.35201e-25
NZ_CP010849.1|WP_044380206.1|1664122_1665580_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.03784e-87
NZ_CP010849.1|WP_078969091.1|1661719_1662004_-|zf-TFIIB-domain-containing-protein	gnl|CDD|379195	pfam13453, zf-TFIIB, Transcription factor zinc-finger.	9.3644e-17
NZ_CP010849.1|WP_044380220.1|1674853_1675681_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270315	cd13597, PBP2_lipoprotein_Tp32, The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum binds L-methionine; the type 2 periplasmic-binding protein fold. This group includes the lipoprotein Tp32, a periplasmic component of a methionine uptake transporter system, and its closely related homologs. The Tp32 has both structural and sequential homology to the MetQ family of substrate-binding protein, and thus it belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	3.53151e-126
NZ_CP010849.1|WP_078969092.1|1662084_1663221_-|aminoglycoside-phosphotransferase-family-protein	gnl|CDD|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	1.49059e-08
NZ_CP010849.1|WP_044380211.1|1666591_1667824_-|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	6.64343e-108
NZ_CP010849.1|WP_044380235.1|1680253_1681420_-|glycerophosphodiester-phosphodiesterase	gnl|CDD|176544	cd08602, GDPD_ScGlpQ1_like, Glycerophosphodiester phosphodiesterase domain of Streptomycin coelicolor (GlpQ1) and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in a group of putative bacterial and eukaryotic glycerophosphodiester phosphodiesterases (GP-GDE, EC 3.1.4.46) similar to Escherichia coli periplasmic phosphodiesterase GlpQ, as well as plant glycerophosphodiester phosphodiesterases (GP-PDEs), all of which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols. The prototypes of this family include putative secreted phosphodiesterase encoded by gene glpQ1 (SCO1565) from the pho regulon in Streptomyces coelicolor genome, and in plants, two distinct Arabidopsis thaliana genes, AT5G08030 and AT1G74210, coding putative GP-PDEs from the cell walls and vacuoles, respectively.	1.4773e-168
NZ_CP010849.1|WP_044380231.1|1679128_1679626_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.94411e-13
NZ_CP010849.1|WP_044380194.1|1658287_1659112_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.66263e-10
NZ_CP010849.1|WP_044380196.1|1659164_1659986_-|aminodeoxychorismate-lyase	gnl|CDD|238800	cd01559, ADCL_like, ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.	8.58413e-85
NZ_CP010849.1|WP_044380218.1|1674046_1674682_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.27539e-30
NZ_CP010849.1|WP_044380225.1|1676495_1677605_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|236863	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional.	5.22975e-169
NZ_CP010849.1|WP_044380209.1|1665644_1666463_-|RNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	1.25285e-60
NZ_CP010849.1|WP_044380222.1|1675761_1676499_-|ABC-transporter-permease	gnl|CDD|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	4.95306e-99

Protein sequences

>NZ_CP010849.1|WP_044380211.1|1666591_1667824_-|uroporphyrinogen-III-C-methyltransferase
MAEHPAYPVGLRLTGRRVVVLGGGQVAQRRLPALIAAGADIVLVSPEATPSVEAMADAGEITWRKRRYEDGDLADAWYALIATSDRPANEAASAEAERNRVWCVRSDDADAATAWTPATGHSEGVTVAVLTTDARGRDPRHTAAVRDAVVEGLRDGTLVAPHHRTRVPGVALVGGGPGDPDLITVRGRRLLAEADVVIADRLGPRDLLAELPPHVEVIDAAKIPYGRFMAQEAINNALIEHAKQGKSVVRLKGGDPFVFGRGMEEAQALAEAGIPCTVVPGISSSISVPGAAGIPVTHRGVAHEFTVVSGHVAPDDERSLVDWPSLAKLTGTLVILMGVDKIGRIAETLVAHGKAPDTPVALVQEGTTAAQRRVDATLATVAETVRAQEVKPPAVIVVGEVVHVGPRQTA
>NZ_CP010849.1|WP_044380209.1|1665644_1666463_-|RNA-methyltransferase
MAELITVEDPADPRLGDYTDLTDVELRRRREPAEGLFIAEGEKVIRRARDAGYAMRSMLLSAKWVDAMRDVIDASPAPVYVVDPRLAERVTGYHVHRGALASMQRRPLPEAAELVATARRVVVMESVNDHTNIGAIFRSAAALGMDAVLLSPDCADPLYRRSVKVSMGAVFSVPYARLDPWPRSLGTLREAGFTLLALTPDEKATALDEAAPHRMDRVALMLGAEGEGLSRRALAAADEWVRIPMSHGVDSLNVGAAAAVAFYAVATGRPGT
>NZ_CP010849.1|WP_044380206.1|1664122_1665580_+|serine/threonine-protein-kinase
MNMAMMRLRREDPRVVGSFRLHRRLGAGGMGVVYLGSDKKGQRVALKVIRPDLAEDQEFRSRFAREVSAARRIRGGCTARLVAADLEADRPWFATQYVPGPSLHDKVVDEGPLCAADVAAVGAALSEGLVAVHEAGVVHRDLKPSNILLSPKGPRIIDFGIAWATGASTLTHVGTAVGSPGFLAPEQVRGAAVTPATDVFSLGATLAYASMGDSPFGHGSSEVMLYRVVHEEPQLHGVPDALAPLIRACLAKDPEERPSTLQLSLRLKEIAAREAQGLADVRPPAPRAGETDRPTGRLGDSYPERTQRRPQERSGAPGTPVPRGASGARGGTPPRGTASPRGGSASRGGTGSRSERPGSRPRPTPASRNATGRNTGRNTGRNTTRSGGGRPGPRTGGGRPAPRGTGTGLRPANPRLLRQRLFVFVVVTLLVALGIAAAQGCQGPARGLGGDRQDVRQQQELVRPGHTPGEAGTPHAAEPAPGRTG
>NZ_CP010849.1|WP_029387714.1|1663269_1663479_-|hypothetical-protein
MAHTAPRTLIREEGRKAYAAAFRPRRQGRRHPLVATVMALPLAVLLLLVFDGWETVATQASSVGAMLGR
>NZ_CP010849.1|WP_078969092.1|1662084_1663221_-|aminoglycoside-phosphotransferase-family-protein
MKPRGDGGAADGTDAGAAGELRRHCPFPRPARAGAPCRSAAGRRPAARPPPRRGPPANAPYPHPVTTPPPLLPALAERATAAAHARAPGCACGATVTLADRPDATVVRHAATVAKAHAPDTDPDALAARLGAAARLPGILLPPLRPAPVRLRGRHVTFWPYGTPVDPDDPDAAPWEAAATLLARLHRSSLPGLRLPPMRGPVKAAHAVARLRAAAAHPGAVPVLRAWAGLPAWARGEAPPPKTAVVCHGDLHLGQLVRHPAPDGPWLLIDVDDLGVGVPAWDLARPAAWYACGVLPPEQWARFLAAYRSASGPAVPQDGDPWPALDVPARALTVQTAARAVTKAAAEERPLDEVERALVDACARMAALPADPAASGAT
>NZ_CP010849.1|WP_078969091.1|1661719_1662004_-|zf-TFIIB-domain-containing-protein
MQCPKCHGPMHTYNRNGVQIEQCSSCRGIFLDYGELEALTRLESQWAQPAPPPPPAPHAYPAPPVPPAAPAWGAPHGGHGHHRQRSFGRMLFSS
>NZ_CP010849.1|WP_044380199.1|1659982_1661026_-|chloride-transporter
MLELPPLARFGDRVATGLLDVTSDPAALDSSGFWAVCADFEGRLTCARFRDVRREPVPAPVPGGWRGPAVGDWTSSLDRSAYTAAVRRIRAHIAAGEVYQANLCRVLSAPVAPDADVDALTAVLARGNPAPYAGTIRLPEHGVETATASPELFLRRDGRIVESGPIKGTGRTEADLLEKDYAENVMIVDLVRNDIGRVCATGSVTVPDLCVVEKHPGLVHLVSTVRGELRTGAGWPELLDAAFPPGSVTGAPKESALRIIEALETAPRGPYCGGIGWVDADRGTGELAVGIRTFWIDRDEGLLRFGTGAGITWGSDPEGEWRETELKASRLLAVASGAYEVSEGTLR
>NZ_CP010849.1|WP_044380196.1|1659164_1659986_-|aminodeoxychorismate-lyase
MKIWLDGGLQDIESARVSVFDHGLTVGDGIFETVKAVDGRPFALTRHLDRLTRSARGLGLPAPDLDEVRRACAAVLEANPMPLGRLRITYTGGHGPLGSDRGDQGPTLVVALGETARRPDSTAVITVPWTRNERSALAGLKTTSYAENVVALARAHAHGASEALFGNTVGRLCEGTGSNVFVVLDGEIHTPPLASGCLAGITRALAVEWTGARETDLPLEVLERADEIFLTSTLRDIQAVHRVDDRELPGVPGPVTAKAMRVFEERSGDDLDP
>NZ_CP010849.1|WP_044380194.1|1658287_1659112_-|GNAT-family-N-acetyltransferase
MTTTLRPTEPLQRAADGTRSRRFQVCVNSRPVGAIHLGTSPSLGDSVARILDLRIDEPDRRRGRATVAVLAAEEVARSWGCRQVEALVPVTAEAALRLARALGYVPRNRAMSKRLGATPPDLPAGSSARPMTPAEFDAWQAHESERYARTWTERGLAEAAARAKARRDHETLLPRGLGTGDMLFSVLEHDGARVGTLWLALREDRAFVFDVETDAAHRGRGHGRSLMLLAEAQSIAAGRDVLGLNVFAGNTPAERLYESLGYETTQYSYCKTLL
>NZ_CP010849.1|WP_078969090.1|1657560_1658121_+|DsbA-family-protein
MGRRRGDWETGSMSDTSPDRPAAPVLDVWCELQCPDCRTALDDLGALRARYGDRLELRLRHFPLEKHKHAFAAAQAAEEAVAQGKGWEYVEAVLARVEELDRKGEPFLVEAARELGLDAEEFDTALIDGRHILIVDADQAEGKAIGVTGTPTYVIGGERLDGGKSQEGLRERIEEIADRLLGARES
>NZ_CP010849.1|WP_044380215.1|1672686_1673922_-|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE
MADRVTVIGWDGSPLTAAARAALGAATLVAGAAHHLALPEVPPAAERIRLGSVALAARRIAAHRGTAVVLADGDPGFFGVVRTLRAPEFGLEVEVVPAVSSVATAFARAGMPWDDAQVVVAHPRTLRRAVNVCRAHTKVAVLTAPGAGPAELGLLLDEVHRTFVICEELGTTHERVTVVTSDKAADHTWRDPNVVIVIGGPSGPGVAADGGGWIAGRDPAAGPRGWSLPAGAYGGDLGEGETDLLRTAQLARLGPRLGDLVWDIGCGSGAFATEAARGGAAVIAVDRDPDACARTEATARRFGVQLQTVCGTAPHVLEDLPEPDVVRVGGGGAAVVSAVADRRPQRIVTHAATRDAAELVGRDLTEHGYVVECALLQSVALDTRAWTEKERSVAFLLSGELPRREGGAPGR
>NZ_CP010849.1|WP_044380218.1|1674046_1674682_-|GNAT-family-N-acetyltransferase
MTSTFPGISISTERLVLRPLETDDVPALAAMMNDEQVGAWTDVPQPFTEDGARDWITERAPARRAAGRGLDLAVTEFLTQRLVGVIRLTRTNWRVRSTELSYIIAPWARGEGYASEAALATARWLFGDQKFERIELRTAADNTASQQVAQKIGCISEGVLRNACIAHVRAEDGTWTDVRTDFIVWSLLPEDLEGAGGHPADTGFTTFTDWN
>NZ_CP010849.1|WP_044380220.1|1674853_1675681_-|ABC-transporter-substrate-binding-protein
MRNTAKITTAVLAASALTLGLTACGSDKDSASDTSGPLVVAATPVPHAEILTYVKDNLAKKEGLDLEVKEFTDYVTPNTATEDGSVGANYFQTEPYLADFNKKNGTHLKSVASVHLEPLGLYSEKADKPGDLKNGATIAVPNDTVTEARALQLLAANGLLTLKDGVGTEATPADIVKNPKNLKFKELEAAQTPRSLGDVDAAVINGNYALEADLKPAEDALVLESAENNPNVNLLVVKEGNEDDPRVRKLAKLLTSPEVKKFIEDKYAGSVVASF
>NZ_CP010849.1|WP_044380222.1|1675761_1676499_-|ABC-transporter-permease
MTWAEMQPLLEQACRETLVMVGWSTLIAVVAGLPIGVLLVLTDKGGLLQNTLVNKVVGQIVNIGRSLPFIILMVALMNFTRWVTGTTIGSEAAIVPLAIGGIPFFARLVETAVREVDNGLVEAVQAMGGNTWTIVRKVLVPEALPSLIASTTTTIIALIGYSAMAGTVGGGGLGDLAVRYGYQRFETGLMWITVAVLAVVISVIQFAGDYAARSLHRRGGRSGPAPKLRLLKAKEPAAADIEKVA
>NZ_CP010849.1|WP_044380225.1|1676495_1677605_-|ATP-binding-cassette-domain-containing-protein
MITTTGLTKVYRSRGREVTALDGVDLHVREGEVYGVIGQSGAGKSSLIRCINLLERPTSGTVTVAGQDLTALAGRGPRAGRELRQARSRIGMVFQHFNLLSSRTVQDNVELPLEILGKSGKERSRKALELLDLVGLADKAKSYPAQLSGGQKQRVGIARALAGDPKVLLSDEATSALDPETTRSILQLLRDLNRQLGLTVLLITHEMDVVKSICDSAALMERGRIVESGTVGELLATPGSELAAALFPVGGEASADDRTVLDVTFHGEAATQPVISQLSRTYNIDISILGAAIDTVGGLQIGRMRIELPGRYEDNVVPVGFLREQGLQVDVVDVVDATDAADAARAGVTGDAGDTVDDKQSALVKEGAE
>NZ_CP010849.1|WP_044380227.1|1678306_1678666_+|hypothetical-protein
MLDVLMPATGVAALLLAAWCGWAAYRDQPTKDWHFIGMAVVTLLALVQLVVGVVRLAQGEKPDQGTVIFVAYLLGAFACVPAAGFMSLAERTRWGSVTVAAGGVVLAVLEVRLYDIWGG
>NZ_CP010849.1|WP_044380229.1|1678667_1679102_+|hypothetical-protein
MTAAQESASRTRLVGGPGMLLVWLYGVMVVGAVSRSAYQIATEFDRAPLAYSLSAVAGLVYGFITYSLVRGGETARKAALVCCAAELVGVLTVGTWTLIEPSAFPDATVWSDYGMGYVFIPVLLPLSALYWLRKAARAQRPDAG
>NZ_CP010849.1|WP_044380231.1|1679128_1679626_-|GNAT-family-N-acetyltransferase
MGMSVTISAATEQDAEQIFRLQYLCFQDEAALYGNYRIDPLVQTLDSVREEVARDCVFVARLGDEVVGSVRGRVTEDGAASIGRLCVHPRLQGHGIGARLLRAAESALAGERGATRFRLHTGHRGEGNLRLYRRVGYETVGTARGADGVPMVVLEKHAEEYATTA
>NZ_CP010849.1|WP_044380233.1|1679683_1680178_-|sigma-70-family-RNA-polymerase-sigma-factor
MTHELVTNLRPLLTAEVAAEAYASGAEPGDLEQAVWLRLLERLQTDGPPQDVHDWLRSAVRSEGRRTRRALRLERPYPAEPVDDTARDPETLALAAARHRAVREAVRRLPGRCPRLMEALLSPKDLTYREIAGELGISQGSLGPERSRCLGCLRRLLAPEVAAR
>NZ_CP010849.1|WP_044380235.1|1680253_1681420_-|glycerophosphodiester-phosphodiesterase
MGTRESNEQAGGAGRRALLGAAVLGAGGAVLGLPGGTASAAGTRPGGGLRSLPVPTVIGHRGASGYRPEHTLGAYQLALDMGADIVEAGDLVPTRDGHLVCRHEPEIGGTTDVADHPEFAGRKRTKSLDGVVTTGWFTEDFTLAELKTLRATERIPVNRPHNTLYDGRWEIPTFEEVLRWQDEQTRRRGKQVWIYPELKHPTYFRKLGLGLEERVARILRRHGKDGKNSPVILQSFEPTSIQRLDKLVGNPLVVLLSGAGSRPWDFVETGDDRTVADLVTPEGLREIASYAQGIGPTLDLIIPRDPAGRLKEPTTLVSDAHRAGLILHPYTLRNENPFLPADFRRGTDADAYGDVFGAYRAYFATGIDGIFTDHPDTGLLAREEFVNR

Crispr_ID: NZ_CP010849_7

• CRISPR_ID: NZ_CP010849_7
• CRISPR_location: 2228203-2228301
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_7

Consensus_repeat	Method
ACCCTGACCCATCGGACCGGGACC	CRISPRCasFinder

spacers of NZ_CP010849_7

>7.1|2228227|51|NZ_CP010849|CRISPRCasFinder
GCCCATGGGCCCGCCCATCGGACCGGGACCCATCTGGCCCTGCATCGGACC

CRISPR arrays and Neighbor proteins around NZ_CP010849_7

CRISPR arrays

The CRISPR arrays of NZ_CP010849_7

>merge|NZ_CP010849|7|2228203-2228301|CRISPRCasFinder
ACCCTGACCCATCGGACCGGGACCGCCCATGGGCCCGCCCATCGGACCGGGACCCATCTGGCCCTGCATCGGACCACCCTGACCCATCGGACCAGGACC

>NZ_CP010849|7|6|2228203-2228301|CRISPRCasFinder
ACCCTGACCCATCGGACCGGGACC	GCCCATGGGCCCGCCCATCGGACCGGGACCCATCTGGCCCTGCATCGGACC
ACCCTGACCCATCGGACCAGGACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_029386495.1|2233691_2234789_-|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl|CDD|234825
NZ_CP010849.1|WP_044381003.1|2224254_2227401_+|isoleucine--tRNA-ligase	unknown	unknown	gnl|CDD|235681
NZ_CP010849.1|WP_044381014.1|2236222_2237650_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	unknown	unknown	gnl|CDD|179297
NZ_CP010849.1|WP_044381007.1|2229909_2230629_-|YggS-family-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|223402
NZ_CP010849.1|WP_044380993.1|2217108_2218227_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NZ_CP010849.1|WP_044381001.1|2221507_2222287_-|signal-peptidase-II	unknown	unknown	gnl|CDD|237810
NZ_CP010849.1|WP_044381012.1|2234795_2236148_-|putative-lipid-II-flippase-FtsW	unknown	unknown	gnl|CDD|274232
NZ_CP010849.1|WP_007448661.1|2228792_2229077_-|YggT-family-protein	unknown	unknown	gnl|CDD|376765
NZ_CP010849.1|WP_044380995.1|2218325_2219912_-|Na+/H+-antiporter	unknown	unknown	gnl|CDD|129911
NZ_CP010849.1|WP_029386498.1|2237631_2238705_-|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl|CDD|234638
NZ_CP010849.1|WP_044380991.1|2214803_2216420_+|alkaline-phosphatase	unknown	unknown	gnl|CDD|226070
NZ_CP010849.1|WP_044380992.1|2216404_2217001_-|dienelactone-hydrolase	unknown	unknown	gnl|CDD|223489
NZ_CP010849.1|WP_044381006.1|2229138_2229780_-|cell-division-protein-SepF	unknown	unknown	gnl|CDD|377370
NZ_CP010849.1|WP_044381002.1|2222375_2223509_-|TraR/DksA-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224648
NZ_CP010849.1|WP_044380997.1|2220053_2220524_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|225064
NZ_CP010849.1|WP_044380998.1|2220520_2221465_-|RluA-family-pseudouridine-synthase	unknown	unknown	gnl|CDD|161659
NZ_CP010849.1|WP_044381008.1|2230635_2231364_-|peptidoglycan-editing-factor-PgeF	unknown	unknown	gnl|CDD|376831
NZ_CP010849.1|WP_044381010.1|2231360_2232581_-|cell-division-protein-FtsZ	unknown	unknown	gnl|CDD|236468
NZ_CP010849.1|WP_044387670.1|2213769_2214615_+|DsbA-family-protein	unknown	unknown	gnl|CDD|372611
NZ_CP010849.1|WP_044381011.1|2232871_2233666_-|FtsQ-type-POTRA-domain-containing-protein	unknown	unknown	gnl|CDD|135428

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_029386495.1|2233691_2234789_-|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	gnl|CDD|234825	PRK00726, murG, undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional.	2.4921e-140
NZ_CP010849.1|WP_044381003.1|2224254_2227401_+|isoleucine--tRNA-ligase	gnl|CDD|235681	PRK06039, ileS, isoleucyl-tRNA synthetase; Reviewed.	0
NZ_CP010849.1|WP_044381014.1|2236222_2237650_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	gnl|CDD|179297	PRK01438, murD, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional.	0
NZ_CP010849.1|WP_044381007.1|2229909_2230629_-|YggS-family-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|223402	COG0325, COG0325, Predicted enzyme with a TIM-barrel fold [General function prediction only].	3.24567e-80
NZ_CP010849.1|WP_044380993.1|2217108_2218227_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	5.15474e-28
NZ_CP010849.1|WP_044381001.1|2221507_2222287_-|signal-peptidase-II	gnl|CDD|237810	PRK14764, PRK14764, lipoprotein signal peptidase; Provisional.	3.18446e-90
NZ_CP010849.1|WP_044381012.1|2234795_2236148_-|putative-lipid-II-flippase-FtsW	gnl|CDD|274232	TIGR02614, Putative_lipid_II_flippase_FtsW, cell division protein FtsW. This family consists of FtsW, an integral membrane protein with ten transmembrane segments. In general, it is one of two paralogs involved in peptidoglycan biosynthesis, the other being RodA, and is essential for cell division. All members of the seed alignment for this model are encoded in operons for the biosynthesis of UDP-N-acetylmuramoyl-pentapeptide, a precursor of murein (peptidoglycan). The FtsW designation is not used in endospore-forming bacterial (e.g. Bacillus subtilis), where the member of this family is designated SpoVE and three or more RodA/FtsW/SpoVE family paralogs are present. SpoVE acts in spore cortex formation and is dispensible for growth. Biological rolls for FtsW in cell division include recruitment of penicillin-binding protein 3 to the division site. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	3.86043e-137
NZ_CP010849.1|WP_007448661.1|2228792_2229077_-|YggT-family-protein	gnl|CDD|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	0.000237172
NZ_CP010849.1|WP_044380995.1|2218325_2219912_-|Na+/H+-antiporter	gnl|CDD|129911	TIGR00831, Putative_Na+/H+_exchanger_Rv2287/MT2345/Mb2309., Na+/H+ antiporter, bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria, blue green bacteria, yeast, plants and animals. Transporters from eukaryotes have been functionally characterized, and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation, extruding the H+ generated during metabolism, and (2) salt tolerance (in plants), due to Na+ uptake into vacuoles. This model is specific for the bacterial members of this family. [Transport and binding proteins, Cations and iron carrying compounds].	4.32204e-83
NZ_CP010849.1|WP_029386498.1|2237631_2238705_-|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl|CDD|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	5.95319e-165
NZ_CP010849.1|WP_044380991.1|2214803_2216420_+|alkaline-phosphatase	gnl|CDD|226070	COG3540, PhoD, Phosphodiesterase/alkaline phosphatase D [Inorganic ion transport and metabolism].	6.43198e-141
NZ_CP010849.1|WP_044380992.1|2216404_2217001_-|dienelactone-hydrolase	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	1.20408e-20
NZ_CP010849.1|WP_044381006.1|2229138_2229780_-|cell-division-protein-SepF	gnl|CDD|377370	pfam04472, SepF, Cell division protein SepF. SepF accumulates at the cell division site in an FtsZ-dependent manner and is required for proper septum formation. Mutants are viable but the formation of the septum is much slower and occurs with a very abnormal morphology. This family also includes archaeal related proteins of unknown function.	5.95027e-31
NZ_CP010849.1|WP_044381002.1|2222375_2223509_-|TraR/DksA-family-transcriptional-regulator	gnl|CDD|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.5669e-21
NZ_CP010849.1|WP_044380997.1|2220053_2220524_-|GNAT-family-N-acetyltransferase	gnl|CDD|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	2.71081e-20
NZ_CP010849.1|WP_044380998.1|2220520_2221465_-|RluA-family-pseudouridine-synthase	gnl|CDD|161659	TIGR00005, Ribosomal_large_subunit_pseudouridine_synthase_D, pseudouridine synthase, RluA family. In E. coli, RluD (SfhB) modifies uridine to pseudouridine at 23S RNA U1911, 1915, and 1917, RluC modifies 955, 2504 and 2580, and RluA modifies U746 and tRNA U32. An additional homolog from E. coli outside this family, TruC (SP|Q46918), modifies uracil-65 in transfer RNAs to pseudouridine. [Protein synthesis, tRNA and rRNA base modification].	2.11422e-102
NZ_CP010849.1|WP_044381008.1|2230635_2231364_-|peptidoglycan-editing-factor-PgeF	gnl|CDD|376831	pfam02578, Cu-oxidase_4, Multi-copper polyphenol oxidoreductase laccase. Laccases are multi-copper oxidoreductases able to oxidize a wide variety of phenolic and non-phenolic compounds and are widely distributed among both prokaryotes and eukaryotes. There are two main active catalytic sites with conserved histidines that are capable of binding four copper atoms.	3.94938e-84
NZ_CP010849.1|WP_044381010.1|2231360_2232581_-|cell-division-protein-FtsZ	gnl|CDD|236468	PRK09330, PRK09330, cell division protein FtsZ; Validated.	0
NZ_CP010849.1|WP_044387670.1|2213769_2214615_+|DsbA-family-protein	gnl|CDD|372611	pfam13462, Thioredoxin_4, Thioredoxin.	6.63723e-35
NZ_CP010849.1|WP_044381011.1|2232871_2233666_-|FtsQ-type-POTRA-domain-containing-protein	gnl|CDD|135428	PRK05529, PRK05529, cell division protein FtsQ; Provisional.	7.51188e-25

Protein sequences

>NZ_CP010849.1|WP_044381003.1|2224254_2227401_+|isoleucine--tRNA-ligase
MNTPPQYRQVPAQVDLPALEHAVLDFWREQKIFAKSLEQSQGRPEWVFYEGPPTANGMPGAHHIEARVFKDVFPRFRTMRGYHVARKAGWDCHGLPVELAVEKELGFSGKQDIEAYGIAEFNARCRESVTRHTDAFAELTTRMGYWVDLDDAYRTMDPEYVESVWWSLKEIFNKGLLVQDHRVAPWCPRCGTGLSDHELAQGYETVVDPSVYVRFPLTSGPLAGEAALLVWTTTPWTLVSNTAVAAHPEVTYVVATDGEEKLVVAEPLVAKALGEGWETTGQTFTGAEMERWSYQRPFELVDFPAEAHFVVNADYVTTEDGTGLVHQSPAFGEDDLRVCRSYGLPLVNPIRQDGTFEEGLPLVGGVFFKKADEKLTEDLGDRGLLFKHLAYEHSYPHCWRCHTALLYYAQPSWYIRTTAIKDRLLQENEKTNWFPDTVKHGRFGDWLNNNIDWALSRNRYWGTPLPIWRCEEGHLTCVGSRAELTQLTGTDQSGLDPHRPYIDDVTFPCTHEGCSLEAVRVPEVIDAWYDSGSMPFAQWGYPYKNKELFESRYPAQFISEAIDQTRGWFYTLMAVGTLVFDKSSYENVVCLGHILAEDGRKMSKHLGNILQPIPLMDQHGADAVRWFMAAGGSPWAARRVGHGTIQEVVRKTLLTYWNTVAFQALYARTSGWAPSEADPAPAERPLLDRWLLSELHALTDQVTQALEGYDTQRAGKLLSAFVDDLSNWYVRRSRRRFWQGDKAALRTLHEVVETVTKLMAPLTPFITERVWQDLIVPVTPGAPESVHLSSWPEADLDAVDPELSRQMVLVRRLVELGRATRAESGVKTRQPLRRALIAAAGFDSLDPELHTQITEELNVESLASLSEVGGSLVDTTAKANFRALGKRFGKRVQDVAKAIAHTDAAALSLALREGTASVEVDGETITLAPDEVIITETPREGWSVASDSGATVALDLEITEELRRAGLARDAIRLIQEARKNSGLDVADRIALRWTATDAATLAALTEHSALIADEVLATDFAQGEADDTYGETFTDEGLSLTFRLRKA
>NZ_CP010849.1|WP_044381002.1|2222375_2223509_-|TraR/DksA-family-transcriptional-regulator
MAGKTAGKAAAGEVLGEAAARKTAGLKAVAGKDAAGKAAGDRAGAARTPAGKAPAKKTAVRKTAAKKDAAKKDAAKKEAEEKATVKTATVKTATVKTAAAKKAAGRKAAVPEEPPGKAAVAAEPPGKATTVTGTGPAEGTGAGQPAGTSGPAGMSGPTGTAGPAGASGTGAAGGGAAAAGRGDGTPEGGSGPDGAVGSKKSTAKKAGAAQAAEQTGATTVVAKKTPGTATAAKNAVPKARVAAAEPGDLAVRPGEDPWTPEEVEAARGELQSEEARLRAEITSSERSLAGLMRDSGDGAGDDQADTGTKNITREHELALAANAREMLTQTERALERLDAGTYGLCENCGNPIGKARMQAFPRATLCVECKQKQERRY
>NZ_CP010849.1|WP_044381001.1|2221507_2222287_-|signal-peptidase-II
MAEAERIIGTPDIPDGSRAAQERPDGAAAPGGPSGAGKARTPAGGPGAAGTEGSGGTEGSGGAGRADGSEAARPAEPAAPAQEGRAGETEGGAVGRPRGKRRIAVLFAVAAFAYALDLISKMIVVAKLEHHEPIEIVGDWLRFEAIRNAGAAFGFGEAFTVIFTVIAAVVIVVIARLARKLYSLPWAIALGLLLGGALGNLTDRIFRSPGVFQGAVVDFIAPKHFAVFNLADSAIVCGGILIVLLSFRGLDPDGTVHKD
>NZ_CP010849.1|WP_044380998.1|2220520_2221465_-|RluA-family-pseudouridine-synthase
MSTIPEIRTLPVPDGLEGERVDAAISRMFGFSRTKAAELAAAGKVTVDGSVVGKSERVHGGAWLEVEMPQAPAPVQVVAEPVEGMEIVHDDEDVVVIVKPVGVAAHPSPGWTGPTVIGGLAAAGYRISTSGAAERQGIVHRLDVGTSGLMVVAKSERAYTSLKRQFKERTVDKRYHTLVQGHPDPTSGTIDAPIGRHPQHDYKWAVTAEGKPSVTHYDLIEAFRAASLLDVKLETGRTHQIRVHMAAHRHPCVGDLTYGADPTLAKRLRLTRQWLHAVRLGFEHPGSGEWAEFASDYPEDLQKALDQVREETWA
>NZ_CP010849.1|WP_044380997.1|2220053_2220524_-|GNAT-family-N-acetyltransferase
MSAAPYTVRVAEGLADLQACFAVRKEVFVAEQGVPEDIEYDAHDAGAVHVLAVREDGEPLGTGRLLYGEAAAGKTGDGPGTGSLGRLAVTRAARGLGVGAALVRAIEEAARARGLTAVDLHAQTHALGFYERLGYTAYGPIFPDAGIPHRAMRRAL
>NZ_CP010849.1|WP_044380995.1|2218325_2219912_-|Na+/H+-antiporter
MDQLALLFLLLLGALVSVPVGERLGLPAPVLMTVLGIVLALADFVPNVDIPPDLILPLLLPPLLYAAVRRTSWRQFAANKRPIFLLAVALVFVTMVCVAATAHAIVPGLPIAAAFALGALVAPPDPVAATAVAGQLGLPRRLVSILEGEGLFNDVTAIVLYHVAIAAAVGGTFSPWRAGLDLVLSAVVAVAVGLALGWGASKLLDLLGDATLQIGLTLLVPYMSYVLAEELHGSGVLAVLTTAMFLAEYAADADDVMTRLAGHTVWDVVDTLVTGVAFGLIGLELHNAVHTASGRWGELLGWAAAIVAVVVLVRLLWLLPATWLTKRLHARRDHDEDIPMSWRETVVMWWSGMRGVASVALALAIPLETDDGSPFPHREEIIFIAFGVIMGTLLVQGFTLPWLVGRLGVRADTEREKAFEKELALRAARAAKRRLKEIEAVEELPEELSEQMLRRAFDIGARISPDIGDEERREAHEQRVRRLKRIRRIQGELLSAARHEVLAARSEPGADPEIVDRVLRHLDVRSLR
>NZ_CP010849.1|WP_044380993.1|2217108_2218227_+|mechanosensitive-ion-channel-family-protein
MENILRPLIVVGGSVVLTLVIGWATDLLLRKADDRNHDTPLWGLLRRGRIPYQLVLCTALLRGSYVEAGLFPSHRAGIGRTLSLVLIGSAAWLVIRIASAVVETSYTRYANARAGRDPARVRRVRTQVTLIMRVVAAVVGVVAGASMLLTFPDMRTAGASLLASAGVLGIVAGIAAQSTLGNLFAGLQIAFGDMVRIGDTVVVDGEWGTVEEITLTFLTVRTWDERRITMPVSYFTSKPFENWSRGTPQMTGIVYWHLDHAAPLDAMRDKLRDILRTCPAWDGRAYDLTVTDTTPTTMQVRALVTAKDADDIWTVRVTVREQIIRWLAEAHPYALPRVAVGDAFPPPGHDGLRRSSPDGAARRLPEQSRQGR
>NZ_CP010849.1|WP_044380992.1|2216404_2217001_-|dienelactone-hydrolase
MNIMLFHSTYGLTPAVRSAADRLRDAGHQVWTPDLFEGRTFDSVEEGRAFKDEVGKDELLKRAVLAAAPYSERGLVYAGFSLGASIAQTLALGDDKARGLLLLHGTSDLAPNASVDGLPVQLHVAEPDPFEPDDWLSAWYLQMGRAGADVEVYRYAGAGHLYTDPALPDYDEEAAEATWRVALGFLASLEEETPQTGS
>NZ_CP010849.1|WP_044380991.1|2214803_2216420_+|alkaline-phosphatase
MPSRRTVVKAATAGAVLAAPLTAALPARAAAAPAFLHGVASGDPLPDGILLWTRVTPVPEAVPGSGLGPDTEVEWTVARDRAFTDIVAKGTVTATAASDHTVKADVRGLEPATDYWFRFLAGGTVSPAARTRTAPAPDAAVPGLRFGVVSCANWEAGHFAAYRHLAARGDLDAWLHLGDYLYEYGTGEYGTRGTVVRPHAPAHEIRTLADYRVRHGRHKTDPDLQALHAAAPVIAIWDDHEFADNAWPGGAENHTEGAEGSWAARLAAAKQSYFEWMPVRPAIAGTTYRRLRFGRLADLSLLDLRSFRSQQTGIGDGGVDDPDRTLTGRAQMDWLKAGLRTSDTTWRLVGNSVMIAPFAIGSLTADLLRPLAELLGLPREGLALNTDQWDGYTDDRRELLAHLRTHAIRNTVFLTGDIHMAWASDVPYDAGTYPLSDSAATEFVVTSVTSDNLDDIMKVREGTVSAVAAPLIRAANRHVHWVDTDRHGYGVLDVTAERAQMDYYVLSDRTRADATASWARSYRTRSGTQKVERVYDPV
>NZ_CP010849.1|WP_044387670.1|2213769_2214615_+|DsbA-family-protein
MSKRNSQAAKTAARERLRQERERQAKRDKVKRQIVVACSIVGVLAIAGGIGYAVVQANKPSHWESVADDKVVAPAHTSGKDGTTVTVGKSSAKKTLKIYEDPRCPVCAAFEQTVGSTVDKDVEEGKYKLQFIGGTFLDGDTEKDGKFETGSHGEGSKNAMSALGAALNVSPEAFLDYKAALYSAKWHPSESDDKFKDDDYLIEIADSVPALKGNAKFRDAVEKGTYDAWAVAMSQTFNNNKDGVTGTPSLVMDGKKLTGAGGNAPMTVDEFDKVIDAALKA
>NZ_CP010849.1|WP_007448661.1|2228792_2229077_-|YggT-family-protein
MSVVLDVVYIALMCFLIVLIFRLVMDYVFQFARSWQPGKAMVVVLEATYTVTDPPLKLLRRFIPPLRLGGVALDLSFFVLMIIVYILISIVSRL
>NZ_CP010849.1|WP_044381006.1|2229138_2229780_-|cell-division-protein-SepF
MAGAMRKMAVYLGLVEDDGYDGRGFDPDDDFEPELDPEPERDHRRHEPSHQSHGSHQPQRDEEVRVVQPPAPREPVSRAASLTAESARPARIAPVASITQERASLEKNAPVIMPKVVSEREPYRITTLHPRTYNEARTIGEHFREGTPVIMNLTEMDDTDAKRLVDFAAGLVFGLHGSIERVTQKVFLLSPANVDVTAEDKARIAEGGFFNQS
>NZ_CP010849.1|WP_044381007.1|2229909_2230629_-|YggS-family-pyridoxal-phosphate-dependent-enzyme
MTDRKDELAGNLAKVEERIAAACAAAGRPREDVTLIVVTKTYPAEDVRILAELGVRHVAENRDQDAAPKAAACADLPLTWHFVGQLQTNKVRSVVGYAHHVQSIDRSKLVTVLSREAVRAGREVGCLIQVALDAGESGRGERGGVAPGGIEELADLVARSPGLRLDGLMTVAPLTGEYAGRQRAAFERLMDLSTDLRRAHPAANMVSAGMSADLEQAVAAGATHVRVGTAVLGVRPRLG
>NZ_CP010849.1|WP_044381008.1|2230635_2231364_-|peptidoglycan-editing-factor-PgeF
MIGQRDTVNGAHFAFTDRWGGVSAVPYEELNLGGAVGDDPAAVTANRELAAKTLGVDPARVVWMNQVHGADVAVVDGPWGEDPAPRVDAIVTAERGLALAVLTADCVPVLLADPVAGVAAAAHAGRPGMVAGVVPAAVRAMTGLGADPSRIVARTGPAVCGRCYEVPEAMRAEVAAVEPAAYAETSWGTPALDVSAGVHAQLQRLGVHDRARSRVCTLESHDHFSYRRDRTTGRLAGYVWLD
>NZ_CP010849.1|WP_044381010.1|2231360_2232581_-|cell-division-protein-FtsZ
MAAPQNYLAVIKVIGVGGGGVNAINRMIEVGLKGVEFIAINTDAQALLMSDADVKLDVGRELTRGLGAGANPAVGRKAAEDHREEIEEVLKGADMVFVTAGEGGGTGTGGAPVVANIARSLGALTIGVVTRPFTFEGRRRANQAEDGIAELREEVDTLIVIPNDRLLSISDRQVSVLDAFKSADQVLLSGVQGITDLITTPGLINLDFADVKSVMSEAGSALMGIGSARGDDRAVAAAEMAISSPLLEASIDGARGVLLSISGGSDLGLFEINEAAQLVSEAAHPEANIIFGAVIDDALGDEVRVTVIAAGFDGGQPPARRDNVLGSASAPASSAPKREEPAPARQSESRPSFGSLGSVKPKEEPEPAAPEPVTELPPVAPPPPVPSSRTYTDSAAEELDVPDFLK
>NZ_CP010849.1|WP_044381011.1|2232871_2233666_-|FtsQ-type-POTRA-domain-containing-protein
MAGTTTAARGERQQGSSGPPRVRRPKAPRLRTIVVLAAASLVAALVAGWLVYGSDWLRVHEVSVSGTRVLTPDQVREAADVPVGEPLVSVDTEAIEGRLLSKTPRIDTVDVIRSWPDGIELKVTERTPVLLVQKGRNFIEVDDEGVRFAMVSHAPKDVPLLELALSRRGSSAASLRRFGEDRLVREAVRVAGRIPAAVARDTRVVKVRSYDDISLELRGGRTVAWGSGEKSEAKARALTALMKAEPGARHFDVSVPTAPASAGS
>NZ_CP010849.1|WP_029386495.1|2233691_2234789_-|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase
MHVVLAGGGTAGHIEPALALADALRRQDPTVGITALGTERGLETRLVPERGYELALIPAVPLPRKPTPELITVPGRLRGTIKAAEQILERTKADVVVGFGGYVALPGYLAAKRLGVPIVIHEANARPGLANKIGSRYAAQVAVSTPDSKLRGARYIGIPLRRTIATLDRAAVRPEARAAFGLDPNLPTLLVSGGSQGARRLNEVVQQVAPWLQQAGIQILHAVGPKNELPQVHQMPGMPPYIPVSYLDRMDLAYAAADMMLCRAGAMTVAELSAVGLPAAYVPLPIGNGEQRLNAQPVVKAGGGLLVDDADLTPEWVQQNVLPVLADPHRLYEMSRAASEFGRRDADELLVGMVYEAIAASRAHR
>NZ_CP010849.1|WP_044381012.1|2234795_2236148_-|putative-lipid-II-flippase-FtsW
MPGSRTGRPPVRRAPERPAAPGPAHENPLLRLHARARRAWDRPLTAYYLILGGSALITVLGLVMVYSASQITALQLSLPGSYFFRKQFLAALIGAALLFAASRMPVKLHRALAYPILAGAVFLMALVQVPGIGMSVNGNQNWISIGGPFQLQPSEFGKLALVLWGADLLARKQDKRLLTQWKHMLVPLVPVAFMLLGLIMLGGDMGTAIILTAILFGLLWLAGAPTRLFAGVLSVAALLGVILIKTSANRMARLACIGATDPGPNDSCWQAVHGIYALASGGLFGSGLGASVEKWGQLPEAHTDFIFAVTGEELGLAGTLSVLALFAALGYAGIRVAGRTEDPFVRYAAGGVTTWITAQAVINMGAVLGLLPIAGVPLPLFSYGGSALLPTMFAIGLLIAFARDEPAARAALAMRQPRFGKKRGARGPQGPRRWNTMRRRTSAVRTSGER
>NZ_CP010849.1|WP_044381014.1|2236222_2237650_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase
MGGRQVTEWQGKHVTVAGLGVSGIPAAKVLHGLGARVTVVNDGDDERARAQAAELEALGITVRLGDGATLPEGTELIVTAPGWKPDKPLFTAAERAGVPVWGDVELAWRLRGRDGREAAPWLAVTGTNGKTTTVQMLAAILKAAGLRTAAVGNIGVSLLDAVTGEERYDVLAVELSSYQLHWAPSVRAHSAAVLNLAPDHLDWHGSMEAYARAKGRIYEGNRVACVYNVADKATEDLVREADVEEGCRAVGFTLGTPGPSQLGVVDGILVDRAFVADRHKNAQELAEVGDVDPPAPHNIANALAAAALARAFGVPATAVRDGLRAFRPDAHRIAHVADVDGVAYVDDSKATNTHAAEASLAAYESVVWIAGGLAKGATFDELVAGAAKRLRGAVLIGADRALIREALARHAPEVPVVDLDRTDTGAMLQAVQEARRLARPGDTVLLAPACASMDMFANYNKRGDAFAQAVRELGA
>NZ_CP010849.1|WP_029386498.1|2237631_2238705_-|phospho-N-acetylmuramoyl-pentapeptide--transferase
MMNQILFAGVIGLFLTLVGTPLLIKLLARKGYGQYIRDDGPREHASKRGTPTMGGIAFILATVAAYFLSKVITGKPPTYSGLLVLGLMVGMGLVGFLDDYIKIVKRRSLGLRAKAKMAGQLIVGIAFAVLALQFSDSRGNTPASTKLSFITDFGWTIGPVLFVVWALFMILAMSNGVNLTDGLDGLATGASVLVFGAYTFIGVWQFQESCANALELTNPGACYEVRDPLDLAVVSSALMGACLGFLWWNTSPAKIFMGDTGSLALGGVLAGLAICSRTELLLAILGGLFVLITMSVVIQVGSFRLTGKRVFRMAPLQHHFELKGWSEVLVVVRFWIIQGICVIVGLGLFYAGWAADK

Crispr_ID: NZ_CP010849_8

• CRISPR_ID: NZ_CP010849_8
• CRISPR_location: 2586336-2586430
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_8

Consensus_repeat	Method
CCGTCCCAGGCCGAGGGCGACCG	CRISPRCasFinder

spacers of NZ_CP010849_8

>8.1|2586359|49|NZ_CP010849|CRISPRCasFinder
CGACGACGAGCGCGACACGCCCGACCGCCAGTCCCCGCCGCGCCCGACG

CRISPR arrays and Neighbor proteins around NZ_CP010849_8

CRISPR arrays

The CRISPR arrays of NZ_CP010849_8

>merge|NZ_CP010849|8|2586336-2586430|CRISPRCasFinder
CCGTCCCAGGCCGAGGGCGACCGCGACGACGAGCGCGACACGCCCGACCGCCAGTCCCCGCCGCGCCCGACGCCGTCCCAGGCGGAGGGCGACCG

>NZ_CP010849|8|7|2586336-2586430|CRISPRCasFinder
CCGTCCCAGGCCGAGGGCGACCG	CGACGACGAGCGCGACACGCCCGACCGCCAGTCCCCGCCGCGCCCGACG
CCGTCCCAGGCGGAGGGCGACCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044381382.1|2600984_2602277_-|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|235098
NZ_CP010849.1|WP_044381375.1|2592243_2593977_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP010849.1|WP_044381363.1|2579233_2580700_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|226951
NZ_CP010849.1|WP_044381361.1|2578170_2579208_+|rod-shape-determining-protein	unknown	unknown	gnl|CDD|336482
NZ_CP010849.1|WP_044381365.1|2581746_2582115_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP010849.1|WP_044381377.1|2593976_2595905_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP010849.1|WP_044381366.1|2582340_2583051_+|ANTAR-domain-containing-protein	unknown	unknown	gnl|CDD|198080
NZ_CP010849.1|WP_044381374.1|2590659_2592114_+|sugar-kinase	unknown	unknown	gnl|CDD|198375
NZ_CP010849.1|WP_078969131.1|2602359_2603166_-|sirohydrochlorin-chelatase	unknown	unknown	gnl|CDD|225049
NZ_CP010849.1|WP_044381369.1|2584371_2584941_+|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|213983
NZ_CP010849.1|WP_044381371.1|2584937_2585408_+|DUF2243-domain-containing-protein	unknown	unknown	gnl|CDD|370775
NZ_CP010849.1|WP_044381379.1|2597590_2599498_-|DNA-primase	unknown	unknown	gnl|CDD|235551
NZ_CP010849.1|WP_044381368.1|2583167_2584370_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044381385.1|2603478_2604060_+|DUF488-domain-containing-protein	unknown	unknown	gnl|CDD|377317
NZ_CP010849.1|WP_044381360.1|2574233_2577848_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173815
NZ_CP010849.1|WP_044381381.1|2599586_2600852_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|170080
NZ_CP010849.1|WP_078969129.1|2580736_2581750_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|379605
NZ_CP010849.1|WP_063856802.1|2585463_2586324_+|cytochrome-c-oxidase-assembly-protein	unknown	unknown	gnl|CDD|378238
NZ_CP010849.1|WP_078969130.1|2587154_2589404_-|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|368582
NZ_CP010849.1|WP_044381373.1|2590293_2590596_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044381382.1|2600984_2602277_-|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NZ_CP010849.1|WP_044381375.1|2592243_2593977_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.52253e-159
NZ_CP010849.1|WP_044381363.1|2579233_2580700_+|GAF-domain-containing-protein	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.82138e-13
NZ_CP010849.1|WP_044381361.1|2578170_2579208_+|rod-shape-determining-protein	gnl|CDD|336482	pfam06723, MreB_Mbl, MreB/Mbl protein. This family consists of bacterial MreB and Mbl proteins as well as two related archaeal sequences. MreB is known to be a rod shape-determining protein in bacteria and goes to make up the bacterial cytoskeleton. Genes coding for MreB/Mbl are only found in elongated bacteria, not in coccoid forms. It has been speculated that constituents of the eukaryotic cytoskeleton (tubulin, actin) may have evolved from prokaryotic precursor proteins closely related to today's bacterial proteins FtsZ and MreB/Mbl.	2.0347e-140
NZ_CP010849.1|WP_044381365.1|2581746_2582115_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	5.46345e-11
NZ_CP010849.1|WP_044381377.1|2593976_2595905_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP010849.1|WP_044381366.1|2582340_2583051_+|ANTAR-domain-containing-protein	gnl|CDD|198080	smart01012, ANTAR, ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.	3.36113e-15
NZ_CP010849.1|WP_078969131.1|2602359_2603166_-|sirohydrochlorin-chelatase	gnl|CDD|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	3.99442e-29
NZ_CP010849.1|WP_044381369.1|2584371_2584941_+|hemerythrin-domain-containing-protein	gnl|CDD|213983	cd12108, Hr-like, Hemerythrin-like domain. Hemerythrin (Hr) like domains have the same four alpha helix bundle and a similar, but slightly different active site structure than hemerythrin. They are non-heme diiron binding proteins mainly found in bacteria and eukaryotes. Like Hr, they may be involved in oxygen transport or like human FBXL5 (F-box and leucine-rich repeat protein 5), a member of this group, play a role in cellular iron homeostasis.	1.06036e-09
NZ_CP010849.1|WP_044381371.1|2584937_2585408_+|DUF2243-domain-containing-protein	gnl|CDD|370775	pfam10002, DUF2243, Predicted membrane protein (DUF2243). This domain, found in various hypothetical bacterial proteins, has no known function.	2.90178e-50
NZ_CP010849.1|WP_044381379.1|2597590_2599498_-|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP010849.1|WP_044381374.1|2590659_2592114_+|sugar-kinase	gnl|CDD|198375	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases. This subgroup is composed of D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17) from bacteria and eukaryota. They share high sequence similarity with Escherichia coli xylulokinase (EcXK), which catalyzes the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. Some uncharacterized sequences are also included in this subfamily. EcXK exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ might be required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	2.71816e-115
NZ_CP010849.1|WP_044381385.1|2603478_2604060_+|DUF488-domain-containing-protein	gnl|CDD|377317	pfam04343, DUF488, Protein of unknown function, DUF488. This family includes several proteins of uncharacterized function.	6.22755e-31
NZ_CP010849.1|WP_044381360.1|2574233_2577848_-|S8-family-serine-peptidase	gnl|CDD|173815	cd07490, Peptidases_S8_6, Peptidase S8 family domain, uncharacterized subfamily 6. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.34481e-83
NZ_CP010849.1|WP_078969129.1|2580736_2581750_-|sensor-histidine-kinase	gnl|CDD|379605	pfam14417, MEDS, MEDS: MEthanogen/methylotroph, DcmR Sensory domain. MEDS is prototyped by DcmR and is likely to function with the PocR domain in certain organisms in sensing hydrocarbon derivatives. The MEDS domain occurs fused to Histidine Kinase and as stand-alone version. Sequence analysis shows that it is a catalytically inactive version of the P-loop NTPase domain of the RecA superfamily.	3.09558e-43
NZ_CP010849.1|WP_063856802.1|2585463_2586324_+|cytochrome-c-oxidase-assembly-protein	gnl|CDD|378238	pfam09678, Caa3_CtaG, Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG). Members of this family are the CtaG protein required for assembly of active cytochrome c oxidase of the caa3 type, as found in Bacillus subtilis.	5.39959e-43
NZ_CP010849.1|WP_078969130.1|2587154_2589404_-|NACHT-domain-containing-protein	gnl|CDD|368582	pfam05729, NACHT, NACHT domain. This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.	1.80143e-11
NZ_CP010849.1|WP_044381381.1|2599586_2600852_-|FAD-dependent-oxidoreductase	gnl|CDD|170080	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional.	6.98554e-69

Protein sequences

>NZ_CP010849.1|WP_063856802.1|2585463_2586324_+|cytochrome-c-oxidase-assembly-protein
MTAAGPLLLTALLACTAYTAAAARLRRRGDAWPWWRQACCWLAGTVFVAGAALPWQSWLPPFTAHMAAHLAAGMAAPLPAVLARPVTLALRALPVPGRRALLAVLHSRPAAVLAFPPVAAALDIGGLWLLYRAPLPPQTHHSPWLYVHLFAAGWLFTFAVLAVDPLRRRAGLALRAGTLLAAAAAHAVLAKTLWAAGPPGTGYAPADLRRAAPLMYYGGDVVEIALAVALACQWYRAQGRALARRSLPARRHGPGRGGVPGPVPPERTPRPLRPSDHRPRHQEASP
>NZ_CP010849.1|WP_044381371.1|2584937_2585408_+|DUF2243-domain-containing-protein
MTYRRAVAGGALLGIGLAAFVDEAVFHQLLHWHHFYDRSTLGAGLVSDGVLHAGSWLATVAGLFLYADLRRRGGPPRPAWWAGVCLGAGGFQLFDGLVDHKLLRVHQIRYGVDVTPYDWAWNAAALLLLTAGLLLWRRARRTDRSRHRGRMAGLRG
>NZ_CP010849.1|WP_044381369.1|2584371_2584941_+|hemerythrin-domain-containing-protein
MAGITASDADVVALLMRQHGDIRNLFDEVERTGGDERRAAFRRLVHLLAVHETAEEEVVHPFTRASVPDGGKIVDDRLAEEREAKEVLSRLDGMDPDDPKFLPGLLALRLDVMAHARAEERYEFNHIRRSADQARLASMATALRAAEAMAPTHPHPGTESAARNMALGPIAAVMDRTRDAVRKAMGKDG
>NZ_CP010849.1|WP_044381368.1|2583167_2584370_+|hypothetical-protein
MGFNPLEHQGIPLERQLRNWRELNVEPVDPDHGDPYTKCRVITMNGIEVEAILFSHQFARHCPDPEVKRQLAEVRYIEHQQQKAVNWLLPGLASVLETTIAYEQVAVDLTGWVARHEPDPYLKQAYEFGVLEDFDHLYRYANLYEMIEHRKAETIVDGLTEVMPGRPTKFHHRDPVDNVREPYDRTRTDPISKLHALTIMSAEQQTMNFYMNVGPQYMEPIARQLYQEIGLIEEEHVTHYESLVDPGETWWEQLVNHEYNECYLYHSFMEQESDPKVKAVWELHLNMELEHLRIACDLMRRHDGREPAEILAPELPNVLTFEENKQFVRNLLDTQMDLTTLGTGYVRDAHERFERMQEQIHGGEEPPSERVMAQHREMFGREYRLETEGPHPDVASREKD
>NZ_CP010849.1|WP_044381366.1|2582340_2583051_+|ANTAR-domain-containing-protein
MTSAAPPRLAGKLTTLVIEARVDGRRALLAPRGELVHGCADTLAETLARLPAGIERVDLDMAGVAFTDTAGLQFLDVLNDHSHRRAVPVAATNWNGQPRRILELAGLDTTDPLHSTAHRPPCPRPGPGLAGVPAPARSAVALERSERLHDLEAEVEQLRHAIASRPVIDQARGILMATHGCTSDEAWHLLRETSQVSNTKLRTVAAAITSSAGTGGPPLPPALRAALRTALARLRR
>NZ_CP010849.1|WP_044381365.1|2581746_2582115_-|STAS-domain-containing-protein
MGETKVGTQHEAPSRAAVAAPGLTVSPLTGRAGVRMAGEVGLSTRGIWEDALEQAVLEGEDVYYLELSGVTFADVAGVGALVAAAQRLPAGARFVLHRPPHVVPRVLELFWPGQPAIEVSMS
>NZ_CP010849.1|WP_078969129.1|2580736_2581750_-|sensor-histidine-kinase
MSAVAEPAESAESAEPATAFGPVPYSGAPEPTDPFVHPALFYRDDEEYLRGTVPFVREGLAAGEPVAVAVPGERLALIRDALGDAADGVRMLDMREAGRNPGRIIPGVLRAFADAQPEGRRVRIIGEPIWAGRTDTEYPACVQHEALINAAFQGRAVTILCPYDAHRLDERVLADAHATHPTVIPAGPGPARGSGAYAPDDVVARYNEPLPPPARALSFSFDTDSLSQARHVATGEGERLGLTGVRLDDLALVSAELVTNSVVHGGGGGTLRVWDEDGYVVCEVRDRGRLADPLAGRRPAAREQRGGRGLLLVNLVSDLVRVHAGPDGTTVRCWFAR
>NZ_CP010849.1|WP_044381363.1|2579233_2580700_+|GAF-domain-containing-protein
MTDAPRSRLALLLEAVLGVGTDLDPRGTLLRLVDGAAELTGAAHAWLSTTGPEPDLLTGIGSPAAPPGVPDTPHHLRVPIHVEGEEFGALHLAGRAGGGPFTAADEQLLRFLAAQAGIAIANARLYGTARQRERWIEGAAAVTTALLTGDAAGDALTTVAERARRLADAAAGVVLQPTGEGGMVIVAVSAPDDPGGPAGAAIPPGSPVLERLFAGEPVFVEDAATDPRMTTPVRHRFGPSMMLPLRAGGRLIGTLALPRRRGDRPYTGVERALAVQFASQAAVALVLADARRGRERLAVYEDRDRIARDLHDLVVQRLFATGLMLESTQRRTGAGEVEELVDRAVDDLRSTVREVRAAILALQRHPPSPHAGEHPAAPARGPAPAATVRDRVLRETAAAAARLGFAPSTRFTGAVDSRVPDPVADRLLAALRRALAAACRRPGVGRVEVAVDATAALPDGRDAVRLTVRDDGEGGEGGGTTVTWECAV
>NZ_CP010849.1|WP_044381361.1|2578170_2579208_+|rod-shape-determining-protein
MTASLEQLRRCHFAVDLGAARTRVYVKGAGLVVDQPSAAAVNTRTGALIAVGEFAEKMTGRTPDFIRVVRPVSGGTVVDIEMAQRMLRHLLGDKIRRSLRRKPRLRAAACTPHDADPLARRAAVETLVGLGARRVELVDILIAAAVGCGLPVERPEATMIMVCGAHATQVAVLSLGSIVTAERIPVGGEAVDYAIVQHLRHAHELMLPSQSVRPLQLALSGNGLTSNGPASTEIHGRDVATGLARSVQVDTAAVRDAIQTPLTTVLDGIGKVLRDCPPDLVADLADRGIMMVGGSALLPGFDQMLRQATGMPVHIAERPDICAVQGLGTMLEGKIEPLALDPLAG
>NZ_CP010849.1|WP_044381360.1|2574233_2577848_-|S8-family-serine-peptidase
MSRGPVGRTAALLSAGLLAGLLPVTPAAAREAPAGTSGTTPSAAHTVTLVTGDRVTVTELGGGKRAVTVERPEGATGAVRTREADGRLSVVPDEALPHLRAGTLDERLFDVGALMEQGLADSRTGELPLIVTYDEGAPALTPRGAERTRALPSVRGAAVRADKGREFWRAFTRQDGIDGVWLDGRVTARMAESNAQIGTPRAWEAGLTGKGVTVAVLDTGVDADHPDLAGRVAESRSFIEGEQVADRNGHGTHVASTVGGSGAASGGGERGVAPGARLAVGKVLGDQGSGSESQIIAGMEWAAREVKADVVSMSLGSSEASDGTDPMAQAVNTLSRETGALFVVAAGNTGTPSSIGSPGAADAALTVGAVDSADEAAYFTSAGPRFGDNALKPDLSAPGVGILAARSGLSEGSGDYTAMSGTSMATPHVAGVAALLAERHPDWTGAQLKDALMSTSKPLAASAYTLGAGRVSVPDAIGAEVTATGSADFGFFSWPHEANEPVARTVTYTNHSGRDVELSLAVRGAPEGVVTLADTTLTVPAHGTAATTVTGDGTGAPVGETSGRIVASVGGTPVAHTAFGLVKEEERYTLTVHVKDRDGAATAAGLTVQKLAAGADPAPARVGGSGTLKLRLTPGTYSLASFLDVRGSHGADSLGLGFLAAPEVVLDRDREVTLDGRALREIEAEPGRRTETRQLLMEYDRTANGSALFEAVQVPLTYDSVFAAPTGKVTEGTFEYRTVWRLGKPLLEVKGVGEATVQAGGTLAEGRTRLPLVDAGDGPITGARGKAVLARLTDGTDPAALAQDAQDAGAEALFVTDDAPGRLMDWWGTDDNADRPLTIATVNVADAARLREAGRVDMTGTRNTPYVYDLSEGHPGAIPDRDLTYRPGTRQLAVLDTKYHAARPAAGGEFRYSLTDTFRLAIGFKERIDFPAERTEYVSTGTGQRWYESVDLAGGALEQRRGVARYEGGTHAELNWFKPVWHPYLGTGLGWGQQRSGSTLRFNVPGWGDSGPDHTGFGDVYSEDSGMSQTTAIHRDGELLGRSADSTAYVWDAPAGEHTYRLVTDTALDADRWGTGTTGHAEWTFRSAATPEDRWTSLPLINLSFDVGTDLAGEVRGGHRLGIGLAAQYTAGATDTGILGGGRLEVSYDDGTTWKSVRLTGENASWRGTLDVPRGARHVSLRASARDDRGGSVTQEIVRAVGVR
>NZ_CP010849.1|WP_078969130.1|2587154_2589404_-|NACHT-domain-containing-protein
MRRENRRTRLPLWVLGFAVAIPVVVALLWTAWTLGNGKLGAGDQAGVLGFGAAAVGVLLSVASLAVAWLGYRADRRESATATGTAAIADAFAFAVRDEWEAEARLRRLNDPYALPVSWMAADEELVEPWADLIARSDAREVSVTDPADLSGRDDEIGDLFQRRLPIRRLVVLGEPGSGKSMLLVRLLLDLCARRNSGDPVPVLFSLSVWDPAADELIPWLEQQLCTHYPALAAEHDGSTRARALLEHRLVLPLLDGFDEMAPAAQAVALDAINRALPVGHPFLLSSRTAEYRRALTPRSGVPVRLNGAAAIVLEPLGPDTTAAYLARDAGGSRSASAARWSPVLARLGTHSPVGQALDTPLTLFLARTIYNPRPGDGADDLPDPARLCNERDFPDADAVRTHLFEAYIAAAYRPHPGKPCRWTADQAQRYLSFLARHLQARDGGTDITWWTLASGLPRGVMTLLQMATAAAMWLLVVAVAGTAALVYAGGVGSDSFFALLAVPLVVFLLASAAVLLARTRRRVGPAVRLHWRPNRFSAGCTVFAGCGAGLGVGAITEDVSLMAPAALIVGVVTAALMGWRVAPTDLTAKTSPARVLSEDRRALLAFAARMTLYGLVGGPSLAFLAQVADALTSPGYDVRKLGDISAEGVAALAGVGLAVGTMLMVTVVLRTASASWFLARHYYAARRLLPRDLLAFLQDAHENRSVLRQVGAVYQFRHLHLQQQLGTSHRCRAENGSSRQAGMAGGTSG
>NZ_CP010849.1|WP_044381373.1|2590293_2590596_+|hypothetical-protein
MRYRLTFVVGLAVGYVLGTRAGRERYEQLKKSARRVSQNPAVRNTAESAAQQGRQFADKAYHVVSDKVGDRMPDSVTQRVRSLRERGGNGRADDWGTSDT
>NZ_CP010849.1|WP_044381374.1|2590659_2592114_+|sugar-kinase
MGIVAGLDSSPDFTRIVVCDTDTGAVLRQGYAPHPVESPEGGGRPSDIDPQAWLLSLGEAAAGGLLEGVQAIGVSAQANAVVPLDAQGNTVRPAMIGGDKRAQVAAADLVDALGGREAWAQAVGCVPQAAHPVTKLRWLARTEPEAAAHAAVLLQAHDWLVWQLLGRPLRRTTDRGGASGTGYWSAATGAWRPDLVELALGHQAALPEVIGPSDAAGTTPEGLLISAGTGETMAAAFGLGVGLGDAVVSLGASGSVMAVHSEPLVDHSGMITALADATGLHLPVVTTLNAVRALRGTAELLGLPDLESLSELAMKSTPGAHGLVLLPYLEGERTPALPHTAGTLAGLRRESMKPEHLARAAFEGMLCGLADALDVLRGRGVEVRRIFLLGPAAELPAVQAAAPALFGTQVVVPQPADYAAIGAARQAAWALGVSQGTLDPRTPPAWQGAAAQVLEPGEELAAGQAVRQQYVSVREQTHPGAFRA
>NZ_CP010849.1|WP_044381375.1|2592243_2593977_+|ABC-transporter-ATP-binding-protein
MLIRLLRTCLRPYKNTIALLVALQFLQTCATLYLPTLNADIIDHGVVQGDTGYILAYGALMIGISLVQVVCNIGAVYYGARTASALGRDMRAAVFDRVQSFSAREVGHFGAPSLITRTTNDVQQVQMLALMTFTLMVSAPIMCVGGIVMALGLDVPLSGVLVAVVPVLGICVTLIVRRLRPLFRAMQERLDTVNRVLREQITGNRVIRAFVRDEYEQRRFGKANADLTEVALGSGNLLALMFPVVMTVVNVSSIAVVWFGAHRIDSGRMEIGDLTAFLAYLMQIVMSVMMATFMFMMVPRAEVCAERIQEVLDTSSSVVPPTAPVTRLRQRGHLEIRDAGFRYPGAEEPVLRGVRLVARPGETTAVIGSTGSGKSTLLGLVPRLFDATEGEVLVDGVDVRTVEPALLARTVGLVPQKPYLFAGTVATNLRYGNPDATDEELWHALEVAQAREFVERLEGRLDAPIAQGGTNVSGGQRQRLAIARTLVQRPEIYLFDDSFSALDYATDAALRAALARETAESTVVIVAQRVATIRDADRIIVLDEGRVVGTGRHEDLMAGNDTYREIVLSQLTEAEAA
>NZ_CP010849.1|WP_044381377.1|2593976_2595905_+|ABC-transporter-ATP-binding-protein
MAGPAARMMAGGGPDQRTMDFKGSGKRLLAQFKPERVTLWALLLCLVVSVGLSVVGPKILGRATDLVFAGIVGRDMPSGATKEQVLEGMRERGDDGVADMLRSTDFTPGQGIDFTAVGNVLLLALGTFLAAGLLMAVATRLVNRAVNRTVYRLREDVQTKLSRLPLSYFDKRQRGEVLSRATNDIDNMGQTLQQSMGQLINSLLTIIGVLAMMFYVSWILALVSLVTVPLSFVVATRVGKRSQPQFVQQWRTTGTLNAHIEEMYTGHTLVKVFGRQEESAQQFAEQNEALYEAGFKAQFNSGIMQPLMMFVSNLNYVLIAVVGGLRVATGSLSIGDVQAFIQYSRQFSMPLTQVASMANLVQSGVASAERIFELLDAEEQGPDPVPAEKPAELHGRVELERVSFRYDPDKPLIENLSLKVEPGHTVAIVGPTGAGKTTLVNLLMRFYEVSGGRITLDGVDIARMSRDELRAGIGMVLQDTWLFGGTIAENIAYGAAREVTRGEIEEAARAAHADRFIRTLPDGYDTVIDDEGSGVSAGEKQLITIARAFLSDPVILVLDEATSSVDTRTEVLIQKAMAKLAAGRTSFVIAHRLSTIRDADTILVMENGSIVEQGTHHDLLAAGGAYARLYQAQFAQAVVEVD
>NZ_CP010849.1|WP_044381379.1|2597590_2599498_-|DNA-primase
MAGRINDEDVKAVRDAVPIDAVVSEYLQLRNAGGGNLKGLCPFHDEKSPSFQVSPAKGLFHCFGCQEGGDTITFVMKIDHLSFSEAVERLAAQAGITLRYEEGGYNPAHQRGERIRLVEAHKIAAEWYAEQLATSPEAETGRLFLAERGFDQAAALHFGVGYSPQGWDHLTRYLRGKGFSDKELILSGLSQEGRRGPIDRFRGRLMWPIRDIGGEVVGFGARKLYEADTGPKYLNTPDTAIYKKSQVLYGIDLAKKEIAKSSRAVVVEGYTDVMACHLAGVRTAIATCGTAFGGDHIKILRRLLMDNGSARVIFTFDGDAAGQKAALRAFEDDQKFAAETYIAIAPDGMDPCDLRLAKGDEAVADLVEPRTPLFEFALRQIVGRYDLDTPAGRAAALDEAAPVVARIKNSGAQHEVAVQLAGMLGILDTQFVVKRVAQLARWARDRGGKGPAPAPAPRQQYAAAPGRPAPRGPALNLRNPVYATERELLKLALQRPELVSPAFDAYGVDEFTAPPYAAVRQAILDAGGAEPGVRDPQGYLVRVREAAPDDTVRAMVTELAVEAIMLRKEVDETYAGAQLVTVRRRAVERRIRDIQSQLTRLGTHGDPAQSAAVQNELWVLQQYDQALREHGAAAL
>NZ_CP010849.1|WP_044381381.1|2599586_2600852_-|FAD-dependent-oxidoreductase
MVDADQTFVIVGGGLAGAKAAETLRAEGFTGRVILICDERDHPYERPALSKGYLLGKEERDSLFVHEPAWYARHDIELHLGQTVAAIDRAARTVRFGEDGTVVRYDKLLLATGAEPRRLDVPGTDLAGVHHLRRLTHAERLRGVLAALGRDNGHLVVAGAGWIGLEVAAAAREYGAEVTVVEPAPTPLHGVLGPELGELFTELHREHGVRLHFGVRLTEIVGQDGAVLAARTDDGEEHPAHSVLVAIGAAPRTALAEAAGLELADPAHGGGIAVDERLRTSDPDIHAAGDVASFPHALFGTRLRVEHWANALNGGPAAARAMLGRDVVHDRVPYFFTDQYDLGMEYSGWAPPGSYDEVVIRGDAGRREFIAFWVRQGRVLAGMNVNVWDVTDTVQRLIRSRAQVDTEALADPHVPLDSLVP
>NZ_CP010849.1|WP_044381382.1|2600984_2602277_-|deoxyguanosinetriphosphate-triphosphohydrolase
MEGIAPPTAYDPASVARWAPEPDKRPGRTAFQRDRARVLHSAALRRLAGKTQVVTPGSMGTAWDASPRTRLTHSLECAQVGRELGAALGCDPDLVEAACLSHDLGHPPFGHNGEEALNEFAHDCGGFEGNAQSLRLLTRIEPKRFVAGHGTGDLVSVGLNLTRATLDAATKYPWPRGAHPTDPASPKFGVYDDDRPVFAWVREGAPAGRACFEAQVMDWSDDVAYSVHDVEDGLHAGHIDPNCLLADPERQAVFEVAIGRYAPPGTDPEELAEALDRLLDQEWWPHGYDGSAVAQARLKDATSQLIGRFCLAAEGATRQAYGGGRLTRYGAELVVPRPARMECAVLKAIADRYVMQRDEQTRLRADQRIVVAELAEALTARAPDGLDPQFRALFARAGDDRARKRVIVDQIASLTDASARSLHARLTGHL
>NZ_CP010849.1|WP_078969131.1|2602359_2603166_-|sirohydrochlorin-chelatase
MNRTSSGTRTAGGTRTGGGLRPDRPALVLVAHGSRDPRALSTVRALLDRVRALRPGLPVRLGHIELNEPLLPATLAALGDRDAVLVPLLLSRGYHVRRDIPEMAAAAPARTRVAAPLGPHPLLAEALHDRLTEAGWHTPGDPAARRASAVVLAAAGSRDPDARTDTGHTAALLAERLGVPVVPAYASAAAPTVPEAVRALAARGRNRVAVASYFTAPGRFAAECAAAAPWIAAAPLATHPAMPRLVLHRYDEALTAAPATAAPALAPA
>NZ_CP010849.1|WP_044381385.1|2603478_2604060_+|DUF488-domain-containing-protein
MDHDRTDPAGGPPASRPELITFGHGTADREVLARLLREAGVVAVVDVRSAPGSRRNPDMARQRLARWMPDEGFAYRWERRLGGWRKASPDSPDTVWRNASFRGYAAHTRTPEFVAAMDELMDQAGRLRTAVMCGEAVWWRCHRRLIADFAVLARGTGVRHLLHDGRLTAHTPTPGVRLRGDGLLVYDGGDPPP

Crispr_ID: NZ_CP010849_9

• CRISPR_ID: NZ_CP010849_9
• CRISPR_location: 2927023-2927458
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of NZ_CP010849_9

Consensus_repeat	Method
GGCTGCCGCCGGGGCGGGGGCGG	CRISPRCasFinder

spacers of NZ_CP010849_9

>9.1|2927046|38|NZ_CP010849|CRISPRCasFinder
TTGATGGTGCGGGGGTCGACGGGGGTGCCGCGAGGTGC
>9.2|2927107|34|NZ_CP010849|CRISPRCasFinder
ACTCCGCGGGGTCGGCTGCCGCCGGGGCGGGGGC
>9.3|2927164|15|NZ_CP010849|CRISPRCasFinder
TCGCTGGGTGGGATT
>9.4|2927202|18|NZ_CP010849|CRISPRCasFinder
CTCCCGCCGGGTCCCGGT
>9.5|2927243|53|NZ_CP010849|CRISPRCasFinder
CTGACGCCGGACGCGGCGACCTCCGGTCGGGCCGGATTCCGCCGGGCGAGGAC
>9.6|2927319|37|NZ_CP010849|CRISPRCasFinder
TCCGCCCGAACGGGGTCGCCCGACGCCCGGTCGAGCC
>9.7|2927379|15|NZ_CP010849|CRISPRCasFinder
CCGCCAAGACGCGGT
>9.8|2927417|19|NZ_CP010849|CRISPRCasFinder
CCGCCGCCCGGTCGGACCG

CRISPR arrays and Neighbor proteins around NZ_CP010849_9

CRISPR arrays

The CRISPR arrays of NZ_CP010849_9

>merge|NZ_CP010849|9|2927023-2927458|CRISPRCasFinder
GGATCGCGACGGTGCGGGGGGAGTTGATGGTGCGGGGGTCGACGGGGGTGCCGCGAGGTGCGGGGGAGGCCGGGCGGGGGGCGGACTCCGCGGGGTCGGCTGCCGCCGGGGCGGGGGCGGATTCCGCCGGGGCGGGGTGACTCGCTGGGTGGGATTGGCTGCCGCCGGGGCGGGGACGGCTCCCGCCGGGTCCCGGTGACTTCCGCCGGAACGGGGTTGGCTGACGCCGGACGCGGCGACCTCCGGTCGGGCCGGATTCCGCCGGGCGAGGACGGCTCCCGCCGGGGGCGGCGACTTCCGCCCGAACGGGGTCGCCCGACGCCCGGTCGAGCCGGCCCCAGCCGAGGCGGGGACGCCCGCCAAGACGCGGTGACTCCCGCCCGAACCGGGTCGGCCGCCGCCCGGTCGGACCGGACCCCCGCCAGGCCGGGGACGG

>NZ_CP010849|9|8|2927023-2927458|CRISPRCasFinder
GGATCGCGACGGTGCGGGGGGAG	TTGATGGTGCGGGGGTCGACGGGGGTGCCGCGAGGTGC
GGGGGAGGCCGGGCGGGGGGCGG	ACTCCGCGGGGTCGGCTGCCGCCGGGGCGGGGGC
GGATTCCGCCGGGGCGGGGTGAC	TCGCTGGGTGGGATT
GGCTGCCGCCGGGGCGGGGACGG	CTCCCGCCGGGTCCCGGT
GACTTCCGCCGGAACGGGGTTGG	CTGACGCCGGACGCGGCGACCTCCGGTCGGGCCGGATTCCGCCGGGCGAGGAC
GGCTCCCGCCGGGGGCGGCGACT	TCCGCCCGAACGGGGTCGCCCGACGCCCGGTCGAGCC
GGCCCCAGCCGAGGCGGGGACGC	CCGCCAAGACGCGGT
GACTCCCGCCCGAACCGGGTCGG	CCGCCGCCCGGTCGGACCG
GACCCCCGCCAGGCCGGGGACGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044381664.1|2916328_2917867_+|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
NZ_CP010849.1|WP_044381665.1|2917856_2919806_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380546
NZ_CP010849.1|WP_044381674.1|2929179_2929782_+|deaminase/reductase	unknown	unknown	gnl|CDD|334719
NZ_CP010849.1|WP_044381677.1|2931589_2932819_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP010849.1|WP_078969151.1|2932837_2933737_-|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NZ_CP010849.1|WP_044381681.1|2938702_2940127_-|tripeptidyl-aminopeptidase	unknown	unknown	gnl|CDD|283275
NZ_CP010849.1|WP_044381666.1|2920801_2921191_+|D-ribose-pyranase	unknown	unknown	gnl|CDD|183318
NZ_CP010849.1|WP_044381676.1|2930892_2931585_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP010849.1|WP_044387839.1|2919863_2920805_+|ribokinase	unknown	unknown	gnl|CDD|238579
NZ_CP010849.1|WP_029384581.1|2929896_2930700_+|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|366542
NZ_CP010849.1|WP_044381669.1|2923422_2924574_-|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl|CDD|368783
NZ_CP010849.1|WP_044381667.1|2922589_2923426_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|224007
NZ_CP010849.1|WP_052808616.1|2913586_2915152_+|hypothetical-protein	unknown	unknown	gnl|CDD|214361
NZ_CP010849.1|WP_044381680.1|2936538_2938374_+|beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|366376
NZ_CP010849.1|WP_044381679.1|2933991_2934945_-|EamA-family-transporter	unknown	unknown	gnl|CDD|183142
NZ_CP010849.1|WP_044381662.1|2915297_2916332_+|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP010849.1|WP_052808615.1|2912270_2913590_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|226700
NZ_CP010849.1|WP_044381672.1|2928560_2928950_-|tautomerase-family-protein	unknown	unknown	gnl|CDD|379645
NZ_CP010849.1|WP_044387841.1|2924570_2925722_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP010849.1|WP_044381671.1|2927626_2928457_-|ammonia-dependent-NAD(+)-synthetase	unknown	unknown	gnl|CDD|234831

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044381664.1|2916328_2917867_+|sugar-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP010849.1|WP_044381665.1|2917856_2919806_+|substrate-binding-domain-containing-protein	gnl|CDD|380546	cd06323, PBP1_ribose_binding, periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs. Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis D-ribose binding protein (ttRBP) and its mesophilic homologs. Members of this group belong to the type 1 periplasmic binding protein superfamily, whose members are involved in chemotaxis, ATP-binding cassette transport, and intercellular communication in central nervous system. The thermophilic and mesophilic ribose-binding proteins are structurally very similar, but differ substantially in thermal stability.	5.84005e-116
NZ_CP010849.1|WP_044381674.1|2929179_2929782_+|deaminase/reductase	gnl|CDD|334719	pfam01872, RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis. This domain is found in the C-terminus of RibD/RibG, in combination with pfam00383, as well as in isolation in some archaebacterial proteins. This family appears to be related to pfam00186.	3.36948e-23
NZ_CP010849.1|WP_044381677.1|2931589_2932819_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	4.35589e-27
NZ_CP010849.1|WP_078969151.1|2932837_2933737_-|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.1966e-14
NZ_CP010849.1|WP_044381681.1|2938702_2940127_-|tripeptidyl-aminopeptidase	gnl|CDD|283275	pfam05576, Peptidase_S37, PS-10 peptidase S37. These serine proteases have been found in Streptomyces species.	0
NZ_CP010849.1|WP_044381666.1|2920801_2921191_+|D-ribose-pyranase	gnl|CDD|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	2.34439e-66
NZ_CP010849.1|WP_044381676.1|2930892_2931585_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.94372e-73
NZ_CP010849.1|WP_044387839.1|2919863_2920805_+|ribokinase	gnl|CDD|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	3.08201e-114
NZ_CP010849.1|WP_029384581.1|2929896_2930700_+|sugar-phosphate-isomerase/epimerase	gnl|CDD|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	5.81501e-35
NZ_CP010849.1|WP_044381669.1|2923422_2924574_-|dihydrodipicolinate-synthase-family-protein	gnl|CDD|368783	pfam06187, DUF993, Protein of unknown function (DUF993). This family consists of several hypothetical bacterial proteins of unknown function.	0
NZ_CP010849.1|WP_044381667.1|2922589_2923426_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	3.61798e-37
NZ_CP010849.1|WP_052808616.1|2913586_2915152_+|hypothetical-protein	gnl|CDD|214361	CHL00095, clpC, Clp protease ATP binding subunit.	3.46957e-128
NZ_CP010849.1|WP_044381680.1|2936538_2938374_+|beta-N-acetylhexosaminidase	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	2.71226e-128
NZ_CP010849.1|WP_044381679.1|2933991_2934945_-|EamA-family-transporter	gnl|CDD|183142	PRK11453, PRK11453, O-acetylserine/cysteine exporter.	2.18958e-60
NZ_CP010849.1|WP_044381662.1|2915297_2916332_+|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	6.1045e-122
NZ_CP010849.1|WP_052808615.1|2912270_2913590_+|tetratricopeptide-repeat-protein	gnl|CDD|226700	COG4249, COG4249, Uncharacterized protein containing caspase domain [General function prediction only].	0.000583728
NZ_CP010849.1|WP_044381672.1|2928560_2928950_-|tautomerase-family-protein	gnl|CDD|379645	pfam14552, Tautomerase_2, Tautomerase enzyme.	8.85242e-25
NZ_CP010849.1|WP_044387841.1|2924570_2925722_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.46393e-52
NZ_CP010849.1|WP_044381671.1|2927626_2928457_-|ammonia-dependent-NAD(+)-synthetase	gnl|CDD|234831	PRK00768, nadE, ammonia-dependent NAD(+) synthetase.	1.84034e-164

Protein sequences

>NZ_CP010849.1|WP_044387841.1|2924570_2925722_-|Gfo/Idh/MocA-family-oxidoreductase
MTRKTVRIAMNGVTGRMGYRQHLVRSILAIREQGGLDLGDGAVLWPEPILVGRREHALRALAERHGLEHVSTDVDAVLADESVDIYFDAQVTSAREDAIKKAIAAGKHIYTEKPTATGFEGALELARLAAAKGVKHGVVQDKLFLPGLLKLKRLIDGGFFGRVLSVRGEFGYWVFEGDWQEAQRPSWNYRAEDGGGIVVDMFPHWEYVLHELFGRVKSVQALAATHIPQRWDENGKPYDATADDAAYGLFELDGGAIAQINSSWAVRVNRDELVEFQVDGTEGSAVAGLRNCRVQHRSATPKPVWNPDIPATYSFRDQWQEVPDNQEFDNGFKAQWELFLKHVYADAPYHWDLLAGARGVQLAELGLKSSAEGRRVDVPEVAL
>NZ_CP010849.1|WP_044381669.1|2923422_2924574_-|dihydrodipicolinate-synthase-family-protein
MTLRLPDAHGALRAYEPRSEPLALNPGSAFTSRTVFSAAHVVADPYADTTPDGPAAVDWDATLAFRRHLWAHGLGVAEAMDTAQRGMGLDWAGAAELIRRSAAEAKAVGGRIACGVGTDQLATGTLDEVRRAYEEQLAVVEESGAQAILMASRALAATARGPEDYLEVYGHLLRQAAEPVVLHWLGPMFDPALEGYWGSSDLDAATGTFLEVIAAHPDKVDGVKISLLDARREIDLRRRLPQGVRCYTGDDFHYPELIAGDEQGFSHALLGIFDPLGPLAAEAVRVLDTGNTEGFRALLDPTVALSRHLFQAPTRFYKTGVVFLAWLAGHQDHFAMVGGLQSARSLPHFARAYELADGLGLFPDPKLAEERMRTLLSLYGVSQ
>NZ_CP010849.1|WP_044381667.1|2922589_2923426_-|sugar-phosphate-isomerase/epimerase
MTDLLSRFSINQMTVKQLSLPELTAACAESGIRNVGLWREPVRSYGVEAAAKLVRDAGLTVTTLCRGGFLTAIDPGERARALEDNRRAVDEAATLGTDTLVLVSGGLPAGSRDLRGARERIADALAELGPYAEEHGVRLAIEPLHPMYASDRCVVSTLAQALDIAEHFPARQVGVTVDTYHIWWDDTAPAQIARAGADGRIHTFQLADWTTPLPEGVLNGRGQIGDGAVDMREWKGYVEAAGYTGPIEVELFNDALWARDGREVLAETAARFVEHAGG
>NZ_CP010849.1|WP_044381666.1|2920801_2921191_+|D-ribose-pyranase
MKKGGILNRHLSGALAELGHGDGVLVCDAGMPVPDGPRVVDLAFRAGVPSFAEVLDGLLAELVVEGATAAAEVREANPGAAALLGGLFPALRLVPHERLKELSRGARLVVRTGEARPYANVLLRCGVFF
>NZ_CP010849.1|WP_044387839.1|2919863_2920805_+|ribokinase
MNDYDLLVVGSANADLVIGVERRPGPGETVLGSDLAVHPGGKGANQAVAAARLGARTALLARVGADDHGRLLLESQRAAGVDTVGVLVGEDPTGVALITVDPSGDNSIVVSPGANARLGPEDVRAAGSLLHASRVVSAQLEIPLETVVEVVRNLPPGSRFVLNPSPPRPLPGEVLAACDPLIVNEHEARVILGDACVSGEPADWARILLAKGPRSVVVTLGDQGALVASSEGISRVPSVRVDAVDTTGAGDAFTAALAWRLGTGWDLVRAAAYAARVGAAAVTRPGAQASYPTAAEVDALDGGRPGDAAEGAR
>NZ_CP010849.1|WP_044381665.1|2917856_2919806_+|substrate-binding-domain-containing-protein
MATDTLKSRPGASGGLRRLLLDNGALTALVVLVIAMSALSGDFLTADNLLNVGVQAAVTAILAFGVTFVIVSAGIDLSVGSVAALSATVLAWSATEAGVPVALAVVLAVVTGVACGLVNGFLVSYGKLPPFIATLAMLSVGRGLSLVISQGSPIAFPDSVSHLGDTLGGWLPVPVLVMVVMGLITALVLGRTYIGRSMYAIGGNEEAARLSGLRVKRQKLAIYALSGLFAAAAGIVLAARLSSAQPQAAQGYELDAIAAVVIGGASLAGGTGKASGTLIGALILAVLRNGLNLLSVSAFWQQVVIGVVIALAVLLDTVRRKAGATPVAAGTAQGGKGRQAATYVLAAVVAVAVAVVGATSLLHGGDSTGKERKVGLSLSTLNNPFFVQIRAGAEQEAEKRGVDLTVTDAQNDASQQANQLQNFTSEGLGAIVVNPVDSDAAGPAVRSANKADIPVIAVDRGVGKADTAALVASDNVEGGRLGARALAEKLGGKGTIVILQGQAGTSASRERGAGFAEGLRAYPGIKVVAKQPADFDRTKGLDVMTNLLQAHPDIDGVFAENDEMALGAIKALGAKAGRSVQVVGFDGTPDGLKAVEAGTLYASVAQVPKELGRIAVDNALRAADGKRVEELVKVPVKVVTKENVAGFGG
>NZ_CP010849.1|WP_044381664.1|2916328_2917867_+|sugar-ABC-transporter-ATP-binding-protein
MSNADELLRIEGIRKTFPGVVALDGVDFDLRRGEVHVLLGENGAGKSTLIKMLSGAYTPDAGRILAGGEEVRINGAQDSERLGIATIYQEFNLVPDLTVAENIFLGRQPRRFGMIDRKRMEADAAVLLERVGVHVSPRARVRELGIARLQMVEIAKALSLDARVLIMDEPTAVLTSEEVERLFAIVRRLRADGVGIVFITHHLEEIAALGDRVTVIRDGRSVGQVPASTPEDELVRLMVGRSIEQQYPRERPATGTALLKVEGLTRDGVFHDVSFEVRAGEVVGIAGLVGAGRTEVVRAVFGADPYDAGSVRVGDVPLRRHDVNAAMAAGIGLVPEDRKGQGLVLDASVEENLGLVTLRSATRAGLVDLKRQHAAAARVAGQLGVRMAGLGQHVRTLSGGNQQKVVIGKWLLADTRVLILDEPTRGIDVGAKVEIYQLVNELTAQGAAVLMISSDLPEVLGMSDRVLVMAQGRIAGELTAEEATQDAVMALALTTPTSSTDHSNGTEAPGGH
>NZ_CP010849.1|WP_044381662.1|2915297_2916332_+|LacI-family-transcriptional-regulator
MASIKDVAAAAGVSVATVSRALNGHPSVSAAARARVLAAVEELGYRPNAVARSLRTDTTRTLGLVISDVMNPYFTELARSVEEEARALGYSVIIGNADERPDLQDHHVTTLLDRRIDGLLVSPTDGGSPRMLEAARAGTPMVFVDRWIPGVDVPVVRSDGRAAVRDLVAHLHGLGHRRLAIIAGPAATTTGRERVDAFREALAAFGLELPAAYIGQGDFQAASGRRVTEGFLDLPEPPEVVFAADNLMALGALDAVRARGLRVPGDLALAAFDDIPWFVHTDPPVTAVAQPTGELGRAAVRALVDRIEGRTAESVTLPARLVVRRSCGEPDTPQSPSPVQRSTT
>NZ_CP010849.1|WP_052808616.1|2913586_2915152_+|hypothetical-protein
MTEKFNAGARRTLVLAQEEARLLNHHHIGTEHILLGLIHEGESVATTALESLGISLEALRQQVEESIGRGQQAPSGPIPFTPRAKKVLELALREALQLGHSYIGTEHILLGLIREGESVTAQVLVKLGADLNRVRRQVMELLAGRAPSTGEPVAVGAPPRSWPLLDQCGRDLTAAARQSRLDPVVGRDKEIERVVQILARRHRNVPMLVGEPGVGKTAVAFGLARSIAAGDVPSVLQHQTVRSLDLGALLADPQYRGRGTDLLTELLGEVRSHGDLVLFLGGALSPLHLSDGTTNALTLFRSLLGTPGVLFVGSCTTLEFGRRGLEPAIDRSIQAVPVAEPAADDVLEILKSVRGRLEEHHRVSLTDEALKAAASLARDHVPDQRLPGSAIDLLDEASAQVRVREARTDEQRAHAAVQQYAAQIAEVRQAKEEAIDQQDFERAMTLRVREKALIAERRHAEQSAREPADDLPLEITEADVVNALAVYSGTHSPEPPRATPRARQVRPAQPVEHDPYVWSMS
>NZ_CP010849.1|WP_052808615.1|2912270_2913590_+|tetratricopeptide-repeat-protein
MRLPDPHRSRVVLIGAGQYADPGLPDLPAVHRTITDLAGLLTDPYSGVVPEAHCTVLLDEGDLRTVGQRLRAAVSEAEDLLLIYYAGHGLTSEPRHDLYLALPDSEYAYPEFNSLEYDKLRHAVLHSTAANKLVILDCCFSGRAITDTMAGGDGAEIGQLEVAGTYVLTSAARDQLALALAGEDHTAFSGRLMRLLREGIVGGPELLTIEDLYRRLRKTMAAEGLPVPLNRGAGTAGGIALGVNRAFAATAGPELRKQQVAAVQQGKDGDWKGASDVLQKVLDEQVRVLGPEHVDTLRTRQSYAHSLGGAGDTMTAAQMLRRLLADHLRLLGPDHEDTLRTRQFLAVNLGEAGHREEAVGMLRVLLADRGRVLGAEHPHTLRTRHLLARNLLLLGAQDEAVALLRQLVTERERLLGGEHPHTRRAAEDLAEAEGGESGR
>NZ_CP010849.1|WP_044381671.1|2927626_2928457_-|ammonia-dependent-NAD(+)-synthetase
MSEPASIALQQEIARELEVAETFEAEREIERRVAFLAERLTSTGLRCLVLGISGGIDSTAAGRLCQLAVERARAAGHEARFYAMRLPYGVQADEHDAQLALSFIRADEVLTVDIKPASDAALEAVRAGGVSFRDARHEDFVHGNIKARQRMIAQYAVAGARDGLVVGTDHAAEAVSGFFTKFGDGAADLVPLTGLTKRRVRAVAEALGAPAELVWKTPTADLESLDPGKADEEALGVGYDDIDDFLEGKPVDEQVFEKIVGRYRLTDHKRRLPIGP
>NZ_CP010849.1|WP_044381672.1|2928560_2928950_-|tautomerase-family-protein
MPFVRIDALGAGPERLDALGRAVHDALVETLGIPPGDLFQVLTSHDGTTGTLRVGDYLGIHRDEGIVYVAITLRAGRPPERKRALYRRIAELAHGYAGTEPRNVFVSLTENTPADWSLGNGEAQYLADR
>NZ_CP010849.1|WP_044381674.1|2929179_2929782_+|deaminase/reductase
MPIVISEFISLDGVVQAPGGPQEDTDGGFAHGGWSHAFFDPEVVGGAFDAAVAEADALLFGRRTWQAMAGAWPERAGDPFADRMNALPKYVVSRTLREDDLTWNNTTLVPGDDEPVARLRELRASEGRGLLVMGSPTLARTLLSEGLVDELRLIVMPVILGGGKTIFPDDGALRAFEPVSTARAATGAQVCVYRAAAPGS
>NZ_CP010849.1|WP_029384581.1|2929896_2930700_+|sugar-phosphate-isomerase/epimerase
MKLAFSTLGVPGLPLPDVLRLATAHGYHGIELRTHPEEPVHPGLTLAERADVAAAFKAAGVEILGLAGYTRVAAPGDDGPVLAEIRTLLDLARDLGAPYVRVFPGGGEDGQSPEEADATAARRLGTAAEHAADRGVRILLETHDSHRTGAAAMRVLGLVGHRHVGALWDVMHTWLGGEQPSETFAALSPHLGYVQVKDIASADDTTPLPLGTGVLPLTECVEVLSRHGWDGWLCWEYEKRWYEAAAPLPGLLDAGRDHLARLLNESA
>NZ_CP010849.1|WP_044381676.1|2930892_2931585_-|response-regulator-transcription-factor
MSDAPPPIRVLVCDDQALVRTGYVTIFSAQPDMEVVGEAENGHEAVRAAGRLRPDVVVMDIRMPLLDGIQATRQLAGPDAEAPPKVLVVTTFNVDAYVYDALRAGASGFLLKDAPPAELVNGIRTVARGEALLAPAVTRHLIGQFAEHLRPADTSRPARQDVVRALTPRELEVLRQIAEGLSNAEIAAELFITPETVKTYVSRILAKLGLRDRVQAVVLAYRIGLVSSTG
>NZ_CP010849.1|WP_044381677.1|2931589_2932819_-|sensor-histidine-kinase
MSPQLPWDRALLRAPLDWWEERGAFLKDGVLALVLALLAFVPTLSNIGAQIGDLPERSASVLSVGLIVAQTLPLAARRRWPAGCLAVVAGAFAAYQALGFATTFGSLGLYLALYSAGAHEVRFRHGLVGVVSAGYAVLALVLDRLGSPQGIADYLAFYLTLAAFWLVGSTVRTRRAGEEQRRRLAAEVAAAAERARIAGELHDVVTHHVTAMVVQADAAQFQLTSAPDKAGEGLSAVSDTGRRALTELRYLLGVLEATGESASADPARADRAPTLGRLGDLVEQARRSGQPVEFSEQGERRAQSVDVELAAYRVVQEALTNAMKHAAGQTTRVLVRHGEERIEIKVTTDGPTASPGAAPAVRKPDPAGGRGLAGLRARARMVDGELEAGPRPEGGFEVHATIPSKPASE
>NZ_CP010849.1|WP_078969151.1|2932837_2933737_-|CPBP-family-intramembrane-metalloprotease
MSTTSTARHAGGPGPDTGPDGHDARGDRLDRIVRSPLGWMLTGLVGVGLVSGLTATGPGPVPVLGAVAAVAVYWLVMRRVARRSTPEIARRGAGREVLLGGAIGLGFVLVSALLITAFGGYSFSWAGHGFMAVVWPAVMVQIGTAATEELLFRGLALQALEQLWGSRAAIVITGLFFGIAHLGAPGATAWSALAIASEAGVMLGAAFLWRRNIWFVAGLHFAWNTTEQLLGIPVSGHTSKGLFTVDVHGSAVLTGGGFGLEAALVPVVIGVLLAVRMFVLARRGGRLLPRRSARHTQAG
>NZ_CP010849.1|WP_044381679.1|2933991_2934945_-|EamA-family-transporter
MRPSHLALAVLVAAVWGVNFTVIEVGLDHFPPLLFSALRFLVAALPAVFFVGRPKVAWKWIVAVGLALGVAKFGLVFVGMDAGMPAGLSSLVLQIQAVFTAVIAWAALGERPTGLRVTGMLIALAGIGVAAVDEGASGPLGAFALVVAAAACWGVSNVLTRKAAPPDALNFMVWVSTVPVLPLLGLSLLTEGPSRDLAALRALDWAGAGTVVFVAWVATVFGFGAWGWLLRRHPASTVAPFSLLVPVFGVSSAAVFLGESVSPLRWCAAALLVGGVVLTSVPARRLGRGRADRGAEGAGTAVPAVRPVPAAAEEYVR
>NZ_CP010849.1|WP_044381680.1|2936538_2938374_+|beta-N-acetylhexosaminidase
MPDSSTGSSAQPSRRTLLAATAGVTAALAASGTASARTARTGDDALRALLSRMTLEEKVGQLFVTRVYGHSATAPDQADIDANLKEIGVRTAAELIARYRVGGIIYFAWAHNTRDPHQIAVLSDGIQKASLELPRGLPVLVSTDQEHGIVARVGEPATLFPGAMAVGAGGSRSDARTLGRIAGAELRALGIRQDYAPVADVNVNPANPVIGVRSFGSDPRAVAELVAAEVTGYQRAGVAACAKHFPGHGDTAVDSHTGFPVITHTRAQWEELDAPPFRAAIEAGIDSIMTAHLMFPALDASGDPATLSRPILTGILREELGYDGVVVTDSLGMEGVRTKYGDERVPVLALKAGVDQLLNPPRLDLAWNAVLKAVQEGELTEARLDESILRILRLKARLGLFREPYTDPDGVDRVVGTRAHLAAADRIAERTTTLLVNEGDLLPLSRRRTPKLLVVGADPASPSGTTGPPTAVLAGALTELGFTATALSTGTSPSTSTVARAVAAAREADAVVVGTYNVTASSTQKTLVRELLATGKPVVAVAVRNPYDVAHLPDVPAFLAAYSWTDVELRAAARVIAGRAAPRGRLPVPVMRAGDPASVLYPVGHGLRYRR
>NZ_CP010849.1|WP_044381681.1|2938702_2940127_-|tripeptidyl-aminopeptidase
MRKALRWLLALVVLIGTVGTAGAATAAQPEATDIKDRLLAVPGMSLIEEKPYPGYRFFVLYYTQPVDHRDPSKGTFRQRVTVLHKDVSRPTVFYTGGYNVSTTPSRREPTQIVDGNQISMEYRFFTPSRPDPADWTKLDIWQAASDQHRIFEALKPIYTENWISTGGSKGGMTATYYERFYPRDMDGVVAYVAPNDVVNKEDSAYDRFFATVGTKECRDRLNGVQREALVRREPLKEKYAAFAADNGYTFDTVGSLDRAYEAVVLDYVWGFWQYSTLKECDAIPADAPNATDEEIWDSVDTISGFSAYTDQGLSTYTPYYYQAGTQLGAPTIRFPHIEKRYIRYGYQPPRNYVPRSIPMTFQPSAMRDIDTWVRHNAHHMLFVYGGNDPWGAEPFRLGRGARDSYVFTAPGMNHGANVAGLVPEQKALATARILQWAGVASPAVQEDPAAARPLAAFDARLDRRTAEREPALRP

Crispr_ID: NZ_CP010849_10

• CRISPR_ID: NZ_CP010849_10
• CRISPR_location: 3145627-3145741
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_10

Consensus_repeat	Method
GACCCGACCGCCTGGACCGGCGGAACGCTCA	CRISPRCasFinder

spacers of NZ_CP010849_10

>10.1|3145658|53|NZ_CP010849|CRISPRCasFinder
GCGCCTCCGGACACCCCCGCGCGACCGGCGCCCCCAGCCCGGCCGCCGGGGCC

CRISPR arrays and Neighbor proteins around NZ_CP010849_10

CRISPR arrays

The CRISPR arrays of NZ_CP010849_10

>merge|NZ_CP010849|10|3145627-3145741|CRISPRCasFinder
GACCCGACCGCCTGGACCGGCGGAACGCTCAGCGCCTCCGGACACCCCCGCGCGACCGGCGCCCCCAGCCCGGCCGCCGGGGCCGACCCGACCGCCTGGACCAGCGGAACGCTCA

>NZ_CP010849|10|9|3145627-3145741|CRISPRCasFinder
GACCCGACCGCCTGGACCGGCGGAACGCTCA	GCGCCTCCGGACACCCCCGCGCGACCGGCGCCCCCAGCCCGGCCGCCGGGGCC
GACCCGACCGCCTGGACCAGCGGAACGCTCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_029385711.1|3136040_3136730_-|cell-division-ATP-binding-protein-FtsE	unknown	unknown	gnl|CDD|225438
NZ_CP010849.1|WP_044381891.1|3159782_3160256_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP010849.1|WP_029385714.1|3138301_3139408_-|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NZ_CP010849.1|WP_044381878.1|3141239_3142976_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP010849.1|WP_044381886.1|3156279_3157548_+|hypothetical-protein	unknown	unknown	gnl|CDD|370724
NZ_CP010849.1|WP_044381883.1|3151344_3151668_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044381871.1|3137261_3137996_-|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NZ_CP010849.1|WP_044381889.1|3159246_3159660_-|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl|CDD|274649
NZ_CP010849.1|WP_044381887.1|3157665_3159222_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044381881.1|3150285_3151200_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP010849.1|WP_044381876.1|3139505_3140750_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP010849.1|WP_044381870.1|3136975_3137167_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044381884.1|3151819_3154024_+|glycosyltransferase	unknown	unknown	gnl|CDD|367953
NZ_CP010849.1|WP_044381885.1|3154030_3156283_+|bifunctional-glycosyltransferase-family-2-protein/CDP-glycerol:glycerophosphate-glycerophosphotransferase	unknown	unknown	gnl|CDD|367953
NZ_CP010849.1|WP_078969164.1|3148942_3150289_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP010849.1|WP_044381880.1|3147540_3148938_+|carbohydrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224567
NZ_CP010849.1|WP_044381861.1|3131615_3132587_-|PHB-depolymerase-family-esterase	unknown	unknown	gnl|CDD|273828
NZ_CP010849.1|WP_044381864.1|3133823_3134957_-|PDZ-domain-containing-protein	unknown	unknown	gnl|CDD|223864
NZ_CP010849.1|WP_044381863.1|3133296_3133776_-|SsrA-binding-protein-SmpB	unknown	unknown	gnl|CDD|376590
NZ_CP010849.1|WP_029385710.1|3135088_3136006_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|225088

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044381891.1|3159782_3160256_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.19021e-24
NZ_CP010849.1|WP_029385714.1|3138301_3139408_-|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP010849.1|WP_029385711.1|3136040_3136730_-|cell-division-ATP-binding-protein-FtsE	gnl|CDD|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	1.2877e-123
NZ_CP010849.1|WP_044381886.1|3156279_3157548_+|hypothetical-protein	gnl|CDD|370724	pfam09852, DUF2079, Predicted membrane protein (DUF2079). This domain, found in various hypothetical prokaryotic proteins, has no known function.	0.00437777
NZ_CP010849.1|WP_044381878.1|3141239_3142976_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.78139e-104
NZ_CP010849.1|WP_044381863.1|3133296_3133776_-|SsrA-binding-protein-SmpB	gnl|CDD|376590	pfam01668, SmpB, SmpB protein.	3.23826e-87
NZ_CP010849.1|WP_044381889.1|3159246_3159660_-|organic-hydroperoxide-resistance-protein	gnl|CDD|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	1.11319e-70
NZ_CP010849.1|WP_044381881.1|3150285_3151200_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.19203e-74
NZ_CP010849.1|WP_044381876.1|3139505_3140750_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.45106e-84
NZ_CP010849.1|WP_044381871.1|3137261_3137996_-|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	6.87519e-06
NZ_CP010849.1|WP_044381884.1|3151819_3154024_+|glycosyltransferase	gnl|CDD|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	8.57647e-163
NZ_CP010849.1|WP_044381885.1|3154030_3156283_+|bifunctional-glycosyltransferase-family-2-protein/CDP-glycerol:glycerophosphate-glycerophosphotransferase	gnl|CDD|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.44423e-141
NZ_CP010849.1|WP_078969164.1|3148942_3150289_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.91853e-41
NZ_CP010849.1|WP_044381880.1|3147540_3148938_+|carbohydrate-ABC-transporter-substrate-binding-protein	gnl|CDD|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	1.19495e-28
NZ_CP010849.1|WP_044381861.1|3131615_3132587_-|PHB-depolymerase-family-esterase	gnl|CDD|273828	TIGR01840, poly3-hydroxybutyrate_depolymerase_A_precursor, esterase, PHB depolymerase family. This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation].	7.76101e-73
NZ_CP010849.1|WP_044381864.1|3133823_3134957_-|PDZ-domain-containing-protein	gnl|CDD|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	9.35187e-66
NZ_CP010849.1|WP_029385710.1|3135088_3136006_-|ABC-transporter-permease	gnl|CDD|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	1.77062e-54

Protein sequences

>NZ_CP010849.1|WP_044381878.1|3141239_3142976_-|serine/threonine-protein-kinase
MRPVGSKYLLEEPLGRGATGTVWRARQRETAGAEAAVPGQPGETVAIKVLKEELANDADVVMRFLRERSVLLRLTHPNIVRVRDLVVEGDLLALVMDLVDGPDLHRHLRENGPFTPVAAALLTAQIADALAASHADGVVHRDLKPANVLLKQDGDLLHPMLTDFGIARLADSPGLTRTHEFVGTPAYVAPESAEGRPQTSAVDIYGAGILLYELVTGRPPFSGGSALEVLHQHLSAEPRRPSTVPDPLWTVIERCLRKNPDERPSAENLARALRVVAEGVGVHANAARIAAAENVGALLAPDPAPAPVPGTPGAPGDADPTQVLPHSADGAYDPNAATSVLPHTGGPGSDADPTAVLPQRGAADPTAVMPPVPPGQAGGPGQGGQPGQPDEPHPWQNQLRAARDRNEQTQIQYLDPGEDPLRRRPQRQVARPQQPPQPQQPPGPAQQRPRQGYGRPQPYVTPQPPQPQPQRPPQPQPQRYAPPPAPEPRRPAREPRPPRRSANPMRIPGLGCLKGCLFTLVVLFVAGWLVWELSPLQEWIGTGKSYWQQISDWAGDVTGWIQDLGGGSDGGGTGTGTG
>NZ_CP010849.1|WP_044381876.1|3139505_3140750_-|serine/threonine-protein-kinase
MARKIGSRYTAHQILGRGSAGTVWLGEGPEGPVAIKLLREDLASDQELVGRFVQERTALLGLEHPHVVSVRDLVVDGNDLALVMDLVRGTDLRTRLDRERRLPPEAAVAIVADVADGLAAAHAAGVVHRDVKPENILLDMEGPPGPGGSHPALLTDFGVAKLIDTPRRTRATKIIGTPDYLAPEIVEGLPPRASVDIYALATVLYELLAGFTPFGGGHPGAVLRRHVTETVVPLPGIPDELWQLIVQCLAKAPASRLRASELGARLRELLPMLAGMPPLDVDEPGTETVEEAPEEPLAGPPPAGEPAPRRGAVPLVPGAKPADANRDTHTSMRVPGPDELAGGARGTARAPRAAGAPRPGSARNRAAARRRRAALGAGTLVLLAAIGIGTWAATGGDDADAGPRDTGDSAPASP
>NZ_CP010849.1|WP_029385714.1|3138301_3139408_-|peptide-chain-release-factor-2
MAVVDVSEELKSLSSTMESIEAVLDLDKMRADIAVLEEQAAAPSLWDNPDEAQKITSRLSHLQAEVRKAEALRGRIDDLAVLFEMAEEEDDPDTRAEAEVELASVRKALDEMEVRTLLSGEYDAREALVNIRAEAGGVDAADFAEKLQRMYLRWAEQRGYKTEIYETSYAEEAGIKSTTFAVQAPYAYGTLSVEQGTHRLVRISPFDNQGRRQTSFAGVEVLPVVEQSDHVEIDESELRIDVYRSSGPGGQGVNTTDSAVRITHLPTGIVVSCQNERSQIQNRATAMNVLQAKLLERRRQEEQAKMDALKGDGGNSWGNQMRSYVLHPYQMVKDLRTEHEVGNPEAVFNGEIDGFLEAGIRWRKQQEK
>NZ_CP010849.1|WP_044381871.1|3137261_3137996_-|hypothetical-protein
MTKKTRIRVARIAAGAVIAAGASLTAAGAASALEIGVSVGADSDGLDAGVNLDLGDDPETPPTSIPSEPSTEEPPTEEPPTEEPPTEEPPTEEPPTEEPPTEEPPTEEPPTEQPPTDDPGDGGDNGGGPGNGGGNGGGGDNGNGNGGGNGGGDNGNGGGNTGGDNTDTDGGSNPSTQEQGSSALTDTGAEAIPAANANGSGKELAETGAAETTFLLVGAATMIAGGIGFRLLPRLVGGRGGATA
>NZ_CP010849.1|WP_044381870.1|3136975_3137167_+|hypothetical-protein
MTYDRLVCANCAAPVSEGRCPVCRANRERLQQENFFSGLNPMALVALLAILVAAVALLAHQTA
>NZ_CP010849.1|WP_029385711.1|3136040_3136730_-|cell-division-ATP-binding-protein-FtsE
MIRFDNVSKVYPKQNRPALRDVSLEVEKGEFVFLVGSSGSGKSTFLRLILREERASHGQVHVLGKDLARLSNWKVPQMRRQLGTVFQDFRLLPNKTVAENVAFAQEVIGKSRGEIRKSVPQVLDLVGLGGKEDRMPGELSGGEQQRVAIARAFVNRPKLLIADEPTGNLDPQTSVGIMKLLDRINRTGTTVVMATHDQNIVDQMRKRVIELEKGRLVRDQARGVYGYQH
>NZ_CP010849.1|WP_029385710.1|3135088_3136006_-|ABC-transporter-permease
MRAQFVFQEIGVGLRRNLTMTFAVIVSVGLSLALFGGSLLMSDQVNQMKGYWYDKVNVSIFLCNKSDAESDPNCAKGAVTTEQKQQIKTDLDKMSVVAEVLYESQDEAYKHYKEQFGDSPLASSLTPDQMQESYRIKLKDPEKYQVIATAFNGRAGVQSVQDQKGILDNLFKLLGYLNWAARGVMLVMLVVALLLIVNTVRVSAFSRRRETGIMRLVGASGFYIQAPFIMEAAVAGLVGGTIACSFLVLGQYFVIDNGMALSEKLPLINFVGWDAVLTKLPLILAASFLMPALAAFFALRKYLKV
>NZ_CP010849.1|WP_044381864.1|3133823_3134957_-|PDZ-domain-containing-protein
MFAGVLVAGAATGSLPRTDGEDRNSAVTGARSAVLAGGRQEVARAAAEALADGKSPVEAAERAVSRSGDRWAAVYSRGEYEELEEALDGRYTGVGLGARRERDGRIEVTRVRAGSPAETAGIRAGDRLRSIDGEPVDGRPVTEVVSLLRGDATGESAGTAVRLGLQRGTRAWSLTLHRARLSTDSVTVRELSGGATVVKVTAFPRGTGEKVRAAVRRAPAGDGIVLDLRGNSGGLVAEAVTAASAFLDGGLVATYDVDGEQRVLHAESGGDTARPLVALVDGGTMSAAELLAGALKDRGRAVVVGSRTFGKGSVQMPSRLPGGSVAELTVGHYRTPSGRGVDGTGITPDLEVDPDAPAALQRARTVLGGLGQQPPPA
>NZ_CP010849.1|WP_044381863.1|3133296_3133776_-|SsrA-binding-protein-SmpB
MAKEKGRKLIAQNKKARHDYHILDTYEAGLVLTGTEVKSLRQGRASLADGFVQLDGHEAWLHNVHVPEYSQGTWTNHSARRKRKLLLHRVEIDKLESKSQETGHTIVPLALYFKDGRAKIEIALARGKKEYDKRQTLREKQDRREAERAMSAVRRRQRA
>NZ_CP010849.1|WP_044381861.1|3131615_3132587_-|PHB-depolymerase-family-esterase
MTQTRAARRVTVLATLLAALLAAPGRASAASLQEVTGFGTNPGALRMFRYVPDGLPAGRPVVLALHGCTQNAAGYGTGSGWPELADRWGFSVVLPQQQSANNPSSCLNWFQSGDTQRGQGEAASLAQMVDRQLADTGADPSRVYVTGLSAGGGMTAVMMAAYPEKFAAAGIVAGLPYGCAQAAGSPYVCMYVGATQTPRQWGDRVRAARPGYGGPWPTLTVLHGSADYTVRPANMTDLVEQWTDVHGADQTADTTDTVAGYPHQLFRDPSGRVVVETYGITGMGHGQPVDPGTGGEHCGTAGAYALDVGLCAAYRLGRAWGLG
>NZ_CP010849.1|WP_044381880.1|3147540_3148938_+|carbohydrate-ABC-transporter-substrate-binding-protein
MRTTSRTIGTRRTAGKTTRAVTALAAGALAFSLTACGGGDDGDKDKEDGPSGGTEAAPSVTLPKLDGASLEVAAVWTGTEQANFKKVLAEFEKRTGAKVTFVPAQDPIINFLGSKIAGGQPPDVAMLPQPGAIKQAVDKGWAKPLGAEAVKELGENYSRGWQDIGKVGGKQYGVYYKAANKSLIWYNAQVFENAGASEPTTWDELLTTARTVYDSGVTPFSIGGADGWTLTDWFENVYLSQAGPEKYDRLAKHEIKWTDPSVKEALTTLAEIWGEKDYLAGGARGALQTEFPGSVTQTFTGGDQPKAGMVYEGDFVQVNIGETEAEVGTDAKVFPFPAVGDTAPVVSGGDAAVVLKDSKAAQALATFLASPDAATIQAKLGGYLSPNKNVKASAYPNDVQRKIAEALVAAGDDFRFDMSDQAPQAFGGTPGKGEWKVLQDFLKNPKDVAGAQRKLEAEAAAAYGG
>NZ_CP010849.1|WP_078969164.1|3148942_3150289_+|sugar-ABC-transporter-permease
MPPASAAGAPPVPAAPTSHKSVTGTRKTVAALFLLPALVLLGALVVYPIGYSVVRSFYDQSGDGFAGVDNYRALFTDDGIRTALKNNIVWVVFAPAVSTALGLIFAVLTERVRWGTAFKLVVFMPMAISMLAAGIIFRLVYDQDPDKGVANAVWVGVHDTFAQSSAFPKAHPGRESPLEAAGGGAFVTREPVRAGEPVTLPLVGVAPDVMPDDAERAAAPVAEPGKVTGTTWQDFTRGKGVGTPGGVDASELGYAGMRIEAVKDGRVVASTTAADDGTFTLPAAADGAVLRLPADNFKEPYNGLEWLGPSLVTPAIIGAYVWMWAGFAMVLIAAGLASVPRELLEAARVDGAGEWQVFRRVTVPLLAPVLAVVAVTLMINVLKVFDLVFIIAPGSSQDDANVLALELYRKGFAADQPGIASAIAVFLLLLVIPVMWFNIRRLRREVRR
>NZ_CP010849.1|WP_044381881.1|3150285_3151200_+|carbohydrate-ABC-transporter-permease
MTARSEAVAKAAVPSAAVPARRSSLGARLAQGVSGGLVRVFLVVVGLFWLVPTFGLLLSSLRTPRDMAASGWWEVFTEPAQLTFASYEQLLENGDITGSLVNTVLITVPATVLVVVIGSLAGYAFAWMEFPGRDWWFLAVVGLLVVPVQVALIPIAELFGEIGLFGSIIGVILFHVGFGLPFAVFLLRNFFAEIPKELLEAARLDGAGELRLFARVVMPLGGPAIASLGIFQFLWVWNDMLVALIFTDSGSQPITVALQTQVRQFGNNIDVLAPGAFISMVIPLAVFFAFQRQFVSGVMAGAVK
>NZ_CP010849.1|WP_044381883.1|3151344_3151668_+|hypothetical-protein
MPRFRVTAPAYRVQAYPHTCPGPVPARPWSGPEFRERLRRYGDGHAAAHATECAVARAVRRAVPGESGPPPPVPPGERRPAPGATAARAARATVEQPAGPRTVTESL
>NZ_CP010849.1|WP_044381884.1|3151819_3154024_+|glycosyltransferase
MPRFSIIVPSHGVAGRLSQALDSVLAQSFGDFELIPVCDAPDCAAADVAAALAERDPRVTPVHSPPSAGLAGARNAGMRAATGAYLLFLDGDDALVPGALAALDARLAETGEVDVLYFEHERLPWWEGEPANPAAPLLAKTPDGAFSPDAAPRLTGVRLPAWSAAYRRAFLTAHDLRFPAGHFTDIAFCGLAAAGAARMGVLRSVVVRHLVRRQGNRLHLPGAHHTELLDQAESLLTRAAGLDLSPARRTALFEDLFAAILRTATHPRRLPEGRRAFFRRACALHRRHRPAGFRPPAGRLGVQHRLLATGSYAAFRALRGANRAAARVLRGLPRPHGLRTRLLYRWHLCRPLDPELVVYCAYWGRGYACNPAAVHAKARELAPRLRGVFLVEPGQEHTVPEGVDHAVVGSRRYWRVLARAKYLVNNANFAEGVVKRPGSVHLQTQHGTPLKTMGVDQSTYPVVAAASGSFTKLLGRVDRWDYNLSANRHSTQVWERAFPGSYEHLEYGYPRNDVYYTATADDVARIRRELGVPEGRTAVLYAPTHRDHRTGFDTGGLDLEAFCEAAGEDVVVLLRAHYFYDGGGRRGSGRVIDVTAHRSAEDVCLAADALITDYSSIMFDYANLDRPIVVYADDWDVYRETRGVYFDLTAAPPGPVARTPEELARVFRDGSYAGRESAALRAAFRERFCEFDDGRAAERVVRRVLLGEPPEAIPPVTPLAERVPAPAAATLVRS
>NZ_CP010849.1|WP_044381885.1|3154030_3156283_+|bifunctional-glycosyltransferase-family-2-protein/CDP-glycerol:glycerophosphate-glycerophosphotransferase
MPRFSIILPCFKVQGFLRECLDSVLGQCYRDIEVIAVNDCSPDGCGAILDAYAARDSRLRVLHLEENVGLGRARNAGMPHATGDYLFFLDSDDTLTPGALRAMADRLEETGDPDVLVFDYARTYWWGGTRRNVLAHILAETQDGSGDGTFTAAERPEILDLLMVVWNKVYRRDFVEREGFTFPPGYYEDTPWTFPVMLTAGRIATLDRICLNYRQRRQGNILSTTSRKHFDIHEQYARVFAYVDAHPSLARWRPYLHAKMGEHCLDILAKPDRLPPSDKAEFFRRTAEMFRAHRPEGTPVPDGLRVLERGYAGWVLWRQSGRARRELGRRAQRARAAAGARLGRARSAVGPRRPLDPHLVVYSAFSHRGVLGDPAAIYHKAREIAPHLRGVWVLRDEEQAELAERTGLLPPGTDHVILGSASYRRVVGRAAFFVNNVNWPGTLHKRPGSVHIHTHQGTPLKYMGADLLGKPGARLGVDVPQMLRRADRWDYSLVANRHSERVWERAYPCHFTSLRTGSPRNDVLVGAGPDAGREVRARLGVPDGHTVVLYAPTRRDYRRGGLVERLDPARFARDLGAGHTLIVRLHPSLASGPARGLGLSELHRRGIVIDATDEPHVEEVMLASDVLVTDYSALMFDYANLDRPLVVHADDWGAFAASRGAYFDITAEAPGPVTRSYDELVRLFASGAWRDEEAARARAAFRERFCEYDDGRAAERVVRTLMLGEPMTGPAGVPRARRVPAADRDQPASL
>NZ_CP010849.1|WP_044381886.1|3156279_3157548_+|hypothetical-protein
MRPRAWVLVLAAVFALLQLANVTGRDTPDTKNYLAYALSLSGRDKRATAEATIDYVCDGKASLARRAQSVHVVRFHRPDPTARVTTGCREREWRTVETRLRAGQTGGHTVPFMPERFMRIFEVRPGYPAFLVPFVAAFGVTWGLWAASVVVAAAGGVLAFLVLRTLSVPVPLALTGQALYYVLPCGTTAMRPMTEGLLLALTLAALWGCALAVRGRRAGLALAGGSLAALFTVKHSQALFLGVCLAAAGALIAVRRRRRGRPPGRAVPALGLIGLGAALATVVLARLLHYPSESDSLQDLLTGHFARPDRERPWPEFWQLQGNFWGEWLRRQAWQPLFAAALGAGVWGALRRPVFGGFLVAAAATGFLTQAAHPDINIWGERLIVLAWLLPVVGIPLLLEPVVRARVPVPAQGHVSRTEPVR
>NZ_CP010849.1|WP_044381887.1|3157665_3159222_+|hypothetical-protein
MSAGVLVRRTVRGATALPGGRFRRPTPYQVAGLLFWLVMTVAYWRVPLCCDAGQHAAVVERLKADLLHPRHPMADLPGAGSAYYSPLAVAQGAFARLTGLDGWAVLRLAGPLNLLVLLSGLGRFVRVLTPRPWAPVLALAAMTLLWGTERAWWSGYLGLMSMTGNLGYPSAFAIGLAFWAWALTGSRARDAARLRYVGPSGLPGCAGYAGLGLLYGLILLVHPITSVAAALGAVALVAGWQRGWRPAVVGRWALTAGAAVAVAVCWPYFDVLALAGDDSVDAMHRTLYLHLPGQFWLALLGLPALWLRGRRSARDPLVLMFVLECAVVAYGWFSGHYTYGRILGLTLVPPQFALAVELAAPRPWGLRRRLLGLAAAAGACAGFLTVHAGAVVPPALDPVGFAQPPRWPAYDWAARHIRPGEVVITDGYYAVHAIAGYGPNLAAPAWPDPALDERERRRRAADVRAYLAPGSTRAERAAVVRRYHVRWLLLTRWHPVPEEAVVVAWSRRTGEVLARVGG
>NZ_CP010849.1|WP_044381889.1|3159246_3159660_-|organic-hydroperoxide-resistance-protein
MDALYTAAATATHGRDGRAVSSDGKLDLALSAPVELGGDGQGTNPEQLFAAGYAACFGSALGLVGRQAKVDVSDAAVTAEVGIGKQGEGFALAVTLRVELPEGVDEATGRKLVEQAHQVCPYSNATRGNIPVDLVVE
>NZ_CP010849.1|WP_044381891.1|3159782_3160256_+|MarR-family-transcriptional-regulator
MTTPAADWLRLDQQICFSLNAASRAFGGIYRGLLKDLGLTYPQYLVMLVLWEHGELPVKKLGEHLRLDSGTLSPLLKRLEAAGLVRRERSAHDERSVRVRLTGEGEALRERALEVPRRIAAATGFDLDEIRDLRARLDRLTGALDAAAALPQEPVGP

Crispr_ID: NZ_CP010849_11

• CRISPR_ID: NZ_CP010849_11
• CRISPR_location: 3219394-3219469
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_11

Consensus_repeat	Method
CGGGCGCGCGGCCCGGCGCTGAAC	CRISPRCasFinder

spacers of NZ_CP010849_11

>11.1|3219418|28|NZ_CP010849|CRISPRCasFinder
GGGTGCCGCGTCACGGCGGCCCCCGGGC

CRISPR arrays and Neighbor proteins around NZ_CP010849_11

CRISPR arrays

The CRISPR arrays of NZ_CP010849_11

>merge|NZ_CP010849|11|3219394-3219469|CRISPRCasFinder
CGGGCGCGCGGCCCGGCGCTGAACGGGTGCCGCGTCACGGCGGCCCCCGGGCCGGGCGCGCGGCCCGGCGCTGAAC

>NZ_CP010849|11|10|3219394-3219469|CRISPRCasFinder
CGGGCGCGCGGCCCGGCGCTGAAC	GGGTGCCGCGTCACGGCGGCCCCCGGGC
CGGGCGCGCGGCCCGGCGCTGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044381948.1|3226930_3227890_+|2-phospho-L-lactate-transferase	unknown	unknown	gnl|CDD|237443
NZ_CP010849.1|WP_078969168.1|3221045_3224903_-|glycosyltransferase	unknown	unknown	gnl|CDD|224137
NZ_CP010849.1|WP_078648257.1|3218142_3218568_-|DUF3499-domain-containing-protein	unknown	unknown	gnl|CDD|378788
NZ_CP010849.1|WP_044381951.1|3229255_3230233_+|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl|CDD|223200
NZ_CP010849.1|WP_044381933.1|3213324_3214458_-|mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|378434
NZ_CP010849.1|WP_029384338.1|3233085_3233841_+|TIGR03089-family-protein	unknown	unknown	gnl|CDD|274426
NZ_CP010849.1|WP_044381931.1|3210903_3211884_-|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl|CDD|223131
NZ_CP010849.1|WP_044381932.1|3212024_3213176_-|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl|CDD|380414
NZ_CP010849.1|WP_044381945.1|3226314_3226830_+|cysteine-dioxygenase	unknown	unknown	gnl|CDD|380416
NZ_CP010849.1|WP_044381930.1|3208312_3208927_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044381939.1|3219558_3221049_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_078969166.1|3214646_3214817_-|Trm112-family-protein	unknown	unknown	gnl|CDD|225391
NZ_CP010849.1|WP_044381934.1|3214944_3216309_-|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl|CDD|236557
NZ_CP010849.1|WP_078969167.1|3218861_3219311_+|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240574
NZ_CP010849.1|WP_003975777.1|3225268_3225532_-|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP010849.1|WP_044381935.1|3216413_3218030_-|L-lactate-permease	unknown	unknown	gnl|CDD|224535
NZ_CP010849.1|WP_044381949.1|3227886_3229197_+|coenzyme-F420-0:L-glutamate-ligase	unknown	unknown	gnl|CDD|183957
NZ_CP010849.1|WP_078969169.1|3231533_3232964_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|128941
NZ_CP010849.1|WP_029384937.1|3209078_3210536_-|adenosylhomocysteinase	unknown	unknown	gnl|CDD|377487
NZ_CP010849.1|WP_044381953.1|3230295_3231378_-|NDP-sugar-synthase	unknown	unknown	gnl|CDD|224129

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044381948.1|3226930_3227890_+|2-phospho-L-lactate-transferase	gnl|CDD|237443	PRK13606, PRK13606, LPPG:FO 2-phospho-L-lactate transferase; Provisional.	1.02214e-176
NZ_CP010849.1|WP_078969168.1|3221045_3224903_-|glycosyltransferase	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	2.58064e-32
NZ_CP010849.1|WP_078648257.1|3218142_3218568_-|DUF3499-domain-containing-protein	gnl|CDD|378788	pfam12005, DUF3499, Protein of unknown function (DUF3499). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.	6.33696e-58
NZ_CP010849.1|WP_044381933.1|3213324_3214458_-|mannose-6-phosphate-isomerase	gnl|CDD|378434	pfam10432, bact-PGI_C, Bacterial phospho-glucose isomerase C-terminal SIS domain. This is the C-terminal SIS domain of a bacterial phospho-glucose isomerase EC:5.3.1.9 protein which is similar to eukaryote homologs to the extent that the sequence includes the cluster of threonines and serines that forms the sugar phosphate-binding site in conventional PGI. This domain contributes a good proportion of the active catalytic site residues. This PGI uses the same catalytic mechanisms for both glucose ring-opening and isomerisation for the interconversion of glucose 6-phosphate to fructose 6-phosphate. It is associated with family SIS, pfam01380.	9.15504e-19
NZ_CP010849.1|WP_029384338.1|3233085_3233841_+|TIGR03089-family-protein	gnl|CDD|274426	TIGR03089, conserved_hypothetical_protein, TIGR03089 family protein. This protein family is found, so far, only in the Actinobacteria (Streptomyces, Mycobacterium, Corynebacterium, Nocardia, Propionibacterium, etc.) and never more than one to a genome. Members show twilight-level sequence similarity to family of AMP-binding enzymes described by pfam00501.	2.59956e-81
NZ_CP010849.1|WP_044381931.1|3210903_3211884_-|cation-diffusion-facilitator-family-transporter	gnl|CDD|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	4.07316e-39
NZ_CP010849.1|WP_044381932.1|3212024_3213176_-|mannose-6-phosphate-isomerase,-class-I	gnl|CDD|380414	cd07011, cupin_PMI_type_I_N, type I phosphomannose isomerase in eukaryotes and bacteria, N-terminal cupin domain. This subfamily contains type I phosphomannose isomerase (PMI; E.C. 5.3.1.8; also known as mannose-6-phosphate isomerase) found in eukaryotes and some bacteria such as Salmonella enterica. PMI catalyzes the reversible isomerization of fructose-6-phosphate (F6P) and mannose-6-phosphate (M6P), the first committed step in the synthesis of mannosylated glycoproteins. The active site, located within the N-terminal jelly roll-like beta-barrel cupin fold, contains a single essential zinc atom and forms a deep, open cavity large enough to contain M6P or F6P. PMI type I also has a C-terminal beta-barrel fold which has diverged considerably from the N-terminal domain and is not included here. This subfamily contains an alpha helical domain that is found in eukaryotic and some prokaryotic PMIs but is not present in their archaeal counterparts. F6P is a substrate for glycolysis and gluconeogenesis, while M6P is a substrate for production of activated mannose donor guanosine 5'-diphosphate D-mannose, an important precursor of mannosylated biomolecules such as glycoproteins, bacterial exopolysaccharides and fungal cell wall components. PMI is also essential for survival, virulence and possibly pathogenicity of some bacteria and protozoan parasites, as well as for cell wall integrity of certain yeasts. Thus, PMI is a potential target against fungal infections causing serious illness or death.	1.89633e-108
NZ_CP010849.1|WP_044381945.1|3226314_3226830_+|cysteine-dioxygenase	gnl|CDD|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.90991e-24
NZ_CP010849.1|WP_029384937.1|3209078_3210536_-|adenosylhomocysteinase	gnl|CDD|377487	pfam05221, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.	0
NZ_CP010849.1|WP_078969166.1|3214646_3214817_-|Trm112-family-protein	gnl|CDD|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	8.65739e-15
NZ_CP010849.1|WP_044381934.1|3214944_3216309_-|phosphomannomutase/phosphoglucomutase	gnl|CDD|236557	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed.	0
NZ_CP010849.1|WP_078969167.1|3218861_3219311_+|metallopeptidase-family-protein	gnl|CDD|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	6.01016e-27
NZ_CP010849.1|WP_003975777.1|3225268_3225532_-|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.95518e-28
NZ_CP010849.1|WP_044381935.1|3216413_3218030_-|L-lactate-permease	gnl|CDD|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	1.03229e-138
NZ_CP010849.1|WP_044381949.1|3227886_3229197_+|coenzyme-F420-0:L-glutamate-ligase	gnl|CDD|183957	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional.	0
NZ_CP010849.1|WP_078969169.1|3231533_3232964_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|128941	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.	1.16257e-51
NZ_CP010849.1|WP_044381951.1|3229255_3230233_+|DNA-3-methyladenine-glycosylase-2-family-protein	gnl|CDD|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	3.84791e-26
NZ_CP010849.1|WP_044381953.1|3230295_3231378_-|NDP-sugar-synthase	gnl|CDD|224129	COG1208, GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis].	2.23148e-96

Protein sequences

>NZ_CP010849.1|WP_078969167.1|3218861_3219311_+|metallopeptidase-family-protein
MDNPVTPRAAGNGPRRRDRHGRGMRGPIAPPQVPLAMSRAEAFADLVQDSVERLERRWPQLADIDFLVLDVPYLDGPGRVWDDDAVPLGGTVSARDGQRARVVVYRRPVEIRTKGREERAALVHEIVVEQVAELLGLTPETVDPRYDEE
>NZ_CP010849.1|WP_078648257.1|3218142_3218568_-|DUF3499-domain-containing-protein
MVQSRRGPLKSAVPSNVVSPVRRCSRTACGRPAVATLTYVYADSTAVLGPLATYAEPHCYDLCAEHSERLTAPRGWEVVRLLDGSAPARPSGDDLEALANAVREAARPQERAAGAGGGARAADPMEVARRGHLRVLRSPDN
>NZ_CP010849.1|WP_044381935.1|3216413_3218030_-|L-lactate-permease
MYVQELEPVAGSLGLSALVAALPLVLVLVLLGGVRMKAHRAGLTGLLAAVLVAWLAYGMPLDQTLSSAAQGAVFGLFPILWIVVNALWVYRMTVRTRHFDVLRRSFGRLSDDPRIQALVIAFCFGALLEALAGFGAPVAICSVMLVALGFDPVRAAVVALVANTAPVAFGAMGTPVVTLAQVTGLPLDDVASVVGRQTPLLALVVPLVLVGLVDGRRGLRETWVPALACGVAFAVAQFVASNHVSAQLADIGAALAGAGALVAVPHARVPAAEAVRASVLTGVRSEELDEEDPRREVLRAYAPYALIVAIFSVAQIPAVKDWLAGATRTFDWPFLDVAGADGRPVGGNVFTWPIVSTGGTLVLIAGVGTAAVLGVHARVAVEEWLATVRELRFAILTVTSVLALAYVMNLSGQAATIGHFVAAAGAGLAFLSPVLGWFGVAVSGSDTSANALFGALQVTAARESGLSPELLAAANSSGGVLGKMISPQNLTIACAAVGLAGREGDLLRKVLPWSLGLLLVMCLIVVGQSSPVLGWMLP
>NZ_CP010849.1|WP_044381934.1|3214944_3216309_-|phosphomannomutase/phosphoglucomutase
MAADLSQIVKAYDVRGVVPDQWDEALAELFGAAFVEVTGASAVVTGHDMRPSSPGLAGAFARGAAARGADVTEIGLCSTDQLYYASGALDLPGAMFTASHNPARYNGIKLCRAGAAPVGQDSGLADIRALVERWSESGAPQPAAAPGTVTRRDTLADYAAHLRSLVDLASIRPLKVVVDAGNGMGGHTVPSVFAGLPVDVVPMYFELDGTFPNHEANPLDPANLVDLQKRVREEGADLGLAFDGDADRCFVVDEQGDPVSPSAITALVARRELARNGGKGTVIHNLITSWSVPEVVKEHGGTPVRTRVGHSFIKAEMARTGAIFGGEHSAHYYFRAFWNADTGMLAALHVLAALGGQDAPLSALVAEYDRYAGSGEINSTVDDQAARLAAIRAAYEGRPGVTLDELDGLTVTSADWWFNVRPSNTEPLLRLNAEARDEATMAEVRDEALALIRG
>NZ_CP010849.1|WP_078969166.1|3214646_3214817_-|Trm112-family-protein
MPLEAGLLEILACPACHAPLEEQDDELICTGQDCGLAYPVRDGIPVLLVDEARRPA
>NZ_CP010849.1|WP_044381933.1|3213324_3214458_-|mannose-6-phosphate-isomerase
MLDEALLDNPEGLAEADRRGLLRGAAEAGARVRTAARHAAEAGVHALKPDGRPRAVLIAGPGAAATHTADLLGTLAGAGSPVTRLAPTGVAPASGALRWELPGWAGSVDLLLIATPDGTEPGLSLLAEQAYRRGCTVVGVAPARSPLAEAVDGAHGLFLPMATAPYDVEEPLAASAPGVLWALLTPLLALLDRTGLLTAPPDALDKVADRLDRVAERCGPAIATYANPAKTLAAELADALPVVWTEGTSAGPAGRRFAAALAELSGVPAVVAELPEALAAHGALLAGPLAAGADPDDFFRDRVEEPPALHARVVLLRDRPIGSLTAAPAARDVALDHDTPISELEPEEGGELETLAELIAMTDFAAVYLALASKAAS
>NZ_CP010849.1|WP_044381932.1|3212024_3213176_-|mannose-6-phosphate-isomerase,-class-I
MDRLDNTVRPYAWGSPTAIPELLGVEPTGEPQAEMWMGAHPGAPSRTARGTLPEVIESDPRRELGARTVERFGPRLPFLLKILAAGAPLSLQVHPDLDQARRGYEDEERRGVPADAPHRNYKDANHKPELICALTDFDGLCGFRPPAEAARLLDGLGVASLKPYADLLRAHPEDAALREVLTAVLTADPQEMTRTVAEASAACARLGGAYAPYAGIAHHHPGDPGVLAAMLLNHVRLHPGEALYLGAGIPHAYLSGLGVEIMANSDNVLRCGLTPKHVDVPELLRVVRFEAGDPGVLRPEASPDGEEVYETPIDEFRLSRYVLPEGTAAHDLTLPAPQILLCTAGAVRAGEHALTPGASVFVPAGEKAEVSGTGTVFRATVRV
>NZ_CP010849.1|WP_044381931.1|3210903_3211884_-|cation-diffusion-facilitator-family-transporter
MSASGGTKAIVAALLANLSIAVAKFVAFLFSNSSSMLAESVHSLADSGNQALLLLGGKRAQREATPQHPFGYGRERYVYAFLVSIVLFSVGGMFALYEGYEKIKHPHELTHWYWPVGVLVFAIIAEAFSFRTAIKESNVLRGRKSWKEFVRHAKAPELPVVLLEDLGALVGLVLALGGVGLALLTGNGVWDGVGTLCIGVLLILIALILAVETKSLLLGESAGAEEVGKIEAAVVDGDTVTGIIHMRTLHLGPEELLVAAKIAVSHDGTATEIAAAIDAAEARIRDAVPIARVIYLEPDIYSETEAAKGPDREATPGGPVPHGSGH
>NZ_CP010849.1|WP_029384937.1|3209078_3210536_-|adenosylhomocysteinase
MTTVDNRQDFKVADLSLAEFGRKEITLAEHEMPGLMAIREEYAEAQPLKGARITGSLHMTVQTAVLIETLVALGARVRWASCNIFSTQDHAAAAIAVGPNGTPDNPQGVPVFAWKGETLQEYWWCTEQALTWPDSPTGGPNMILDDGGDATLLVHKGVEYEKDGKVPSPDTAESDEHRVILELLTRTLGENPQKWTQLSSEIRGVTEETTTGVHRLYEMQREGTLLFPAINVNDAVTKSKFDNKYGCRHSLIDGINRATDTLIGGKTAVVCGYGDVGKGCAESLRGQGARVIVTEIDPICALQAAMDGYQVTTLDEVVETADIFITTTGNRDIIMADDMAKMKHQAIVGNIGHFDNEIDMAGLARIPGIVKDEVKPQVHTWTFPDGKKIIVLSEGRLLNLGNATGHPSFVMSNSFADQTLAQIELFTKPDAYPTGVYVLPKHLDEKVARLHLDALGVKLTTLRPEQAEYIGVQVEGPYKPDHYRY
>NZ_CP010849.1|WP_044381930.1|3208312_3208927_-|hypothetical-protein
MPRGRYSLHDPHDHTPLAQEHFQCATGPSGWRYVSRLTTPSGDHRGSVDLTLDDLGRPIRLELHAAHWQVRGAALDGVTWVRTDPTGTQATEGNVRAHAFTGTSPAFLVATARLLRLTPSAAATRVRLVAFTDPVLAPRTVDQSWALVDSETHTTDNGPLTVDAYQVTALDTGEQHVVHLAGDVVLAAPGVELEDLESPPSVFS
>NZ_CP010849.1|WP_044381939.1|3219558_3221049_-|hypothetical-protein
MNRTTLSFIAGVTALAAVTGFAALGAPDASGGDAPTGAAARLPVERTSLVCPAPSMSDLAETTYTSFTPVTEGAAGSGGRAELRAAPDKPGGAGGGKDTEVPEVKQEAPGTPVTGTTSGADVPALVGTAEGRLAPGWTVQQTTEVAAGTGRGLLGVTCAEADTDFWFPGASTASDRTDYVHLTNPDDSAAVVDIELYGKDGALKSTVGEGITVQPHTSEPILLSTLGDTEQNDLTVHVNVRSGRVGAAVQALDDRLGGDWLAPSTAPAGTLVVPGIPKDAAAVRLVLFTPGDIDADLKLRLASRSGTITPAGHETVHVKAGLTTTVELGDVTRGEAGSLVLTPTGQSVPVVAAVRVVRGKDSKQETAFIPATAPVGERATSVDNRAGGTTLSLSAPEKTAKVRITASAGSEGGTAVSKTVTVKGGTTQDVEAPVPGGLKGTYALTVEPLSGGPVYAARLLTATEDDTPGFTIQSLPDDRGMVAVPVAEENLTILQE
>NZ_CP010849.1|WP_078969168.1|3221045_3224903_-|glycosyltransferase
MSVHSHTAARQDTAALPEYPRHVVTAVLVSHDGARWLPDALAALLGQERPVQYAVAADTGSADASAHLVTEALGDDRVLHLARRTGFGQAVEEALRAAPVLTPQDLPYLKRPSGWDPATRTWHDDAYDLPDLPHGEPVQWLWLLHDDCAPEPDALAQMLRVVENEYELGRDDVAVVGPKLRGWYDRRQLLEVGVSIANSGRRWTGLDRREQDQGQHDHIRSVLSVSTAGMLIRRDVFERLGGFDRRLPLMRDDVDLCWRVHAAGLRVLVAPEAVVRHAEAASRERRTVDCDGRTTASPHKVDKAGAVYTLLVNTRTATLPWVLLRLVLGTLLRTLAYLVGKVPGQALDEIRGLLSVVLRPERIVAARRLRGRPQIDRAELRALFPPPGATIRATVEQVAGNLVGRSDPESAAGAGRHGGAIESGPGTDDADFLEVEQFARLKRIARKPGPVLFLVLLFFSLVACRGLLGGGALAGGALLPAPAGAGELWSRYADSWHAVGLGGTSSAPPYLAILATLASLLLGSTGLAVTVLLVGSVPLAGVTAYFASRPLVTSRLLRAWAAIAYAFLPAVTGALAGGRIGTAVLAVLLPLLARAGITAGGLAHPSGARGSWRATWAYALLLTLTTAFTPIVWPIAFVLGAGLLVLRHSDITAYGLRFLAQLGTPLLVLAPWSLTLLPFGFFQEAGIDYGPSAASALDLLGTSPGGPGTAHGLMLIGIVLAALAALLRSERRTGIWTAWAVALVGFVFAVLSNGSAWAGPATLVHGIALLGAAALGADGARARVAEQSFGWRQPVAALIAFASAAGPLLLAVGWTVRGADGPLERRDPVQVPAFVAEEGGTRDQARTLVLDSDSAARVRYLLVRGSGVRLGDAEFAAADGGSGRLDKVVANLVAGSGADQADQLGGFAVRYVLVHKGAPRQVARVLDATPGLSRLSEQDGIALWRVDQQVARATIVPGPQKSGAGSGTGSAAPQPVAAGPVEIHTTVPAGPEGRVLRLADAAAEGWTATLDGKPLTPTTVDGWAQGFRLPAAGGRLDVTYDDPFTHTAWLWAQGALAVVLVVLALPGRRRDIDDDLPEEPVAPAPAATGDGRRARRLRAQAEAAEAAGTTDGTEAVTAPAADARSGGGASGDGGLPVPPPGAPPAPVPQQARYGEWDTAASHPEAGYGTYGYPEGSQYGTEAYGQPYHADQGQAGAYQDDQGQTDAYQADPYQTAAYPAGSYQAGPPQPGGYPADPYQQGQYDPYAYDGTASPGTYGQAYPQGYDPEQSPDPHGTGSERPDGSQQ
>NZ_CP010849.1|WP_003975777.1|3225268_3225532_-|WhiB-family-transcriptional-regulator
MTELVQQLLVDDADEELGWQERALCAQTDPESFFPEKGGSTREAKKVCLACEVRSECLEYALANDERFGIWGGLSERERRRLKKAAV
>NZ_CP010849.1|WP_044381945.1|3226314_3226830_+|cysteine-dioxygenase
MNSDSDLQIAGDILEVPHLLQPPREHPSTVAEFAGLARSIAADRSQWEPLVRYDATTRWYHRLRTGPGYEVWLLSWVPGQGSGPHDHGPSSGVLTVLDGTLTERTRRGTRALRPGAQRVFAPGYVHEVVNDALEPAVSLHVYHPGLTEMTMYSARCAPRAVHDASAAPTTA
>NZ_CP010849.1|WP_044381948.1|3226930_3227890_+|2-phospho-L-lactate-transferase
MRIVVLAGGIGGARFLRGLKRAVPDAEITVIGNTGDDIHLFGLKVCPDLDTVMYTLGGGINEEQGWGRADETFHLKEELAAYGIGPEWFGLGDRDFATHIVRTQMMGAGYPLSAVTEALCDRWQPGVRLIPMTDDRVETHVAVEIDGERKAIHFQEYWVRLRASVPAEAVVPVGADQAKPAPGVLEAIAEADVILFPPSNPVVSVGTILAVPGIREAIADAGVPVVGLSPIVGDAPVRGMADKVLAAVGVESTAAAVAEHYGSGLLDGWLVDTVDAAAVERVEAAGIRCRAVPLMMTDLEAAARMAREALALAEEVRAA
>NZ_CP010849.1|WP_044381949.1|3227886_3229197_+|coenzyme-F420-0:L-glutamate-ligase
MTGAPADGYRVWAVPGIPEVREGDDLAKLIASAEPGLADGDVLLVTSKIVSKAEGRLVRAADREAAIDRETVRVVARRGPLRIVENRQGLVMAAAGVDASNTPAGTVLLLPEDPDASARTIRDGLRDALGVTVGVVITDTFGRPWRSGLTDVAIGAAGLRVLDDLRGGTDAHGNPLGATVVATADELAAAGDLVKGKAAGLPVAVVRGLPHVLAEDDGPGARAMVRGARDDMFRLGTSEAVRLAVTQRRTVRSFTDEPVDPGAVRRAVAAAVTAPAPHHTTPWRFVLLESPEIRTRLLDAMRDAWIADLRRDGRSEESIARRIRRGDVLRDAPCLVVPCLVMDGSHTYGDARRDGAEREMFVVAAGAGVQNFLVALAGERLGSAWVSSTMFCRDVVREVLDLPPDWDPMGAVAVGHPAGEPRPRPERNADAFIAVR
>NZ_CP010849.1|WP_044381951.1|3229255_3230233_+|DNA-3-methyladenine-glycosylase-2-family-protein
MAGRFAPRPVRGTPAAVPRQAGAPARTRTWTPDGPLDLALVLGPLRRGPGDPTFRALPDGSVWRASRTPAGPGTLRVTAHGAQVRGEAWGPGAEWLLHHLPSLLGADDDPSAFAPRHRLLATVRHRRPGLRLGRTGLVLESLIPSVLEQKVTTDEAYRAWRLLVRRYGEPAPGPAPERMYVMPAPRTWALIPSWEWHRAGVDDKRASTILRAVRVAARLEEAAGMEPAAAQARLEVVPGIGPWTSAETVQRSHGAPDAVTVGDVHLPGIVGWALAGDRHADDAAMLRLLRPYAGQRHRAARLILLSGRVPPRRAPRMPVGDIARW
>NZ_CP010849.1|WP_044381953.1|3230295_3231378_-|NDP-sugar-synthase
MTEAILLVGGKGTRLRPLTVHTPKPMVRAAGVPFLTHQLARARAAGVEHIVLATSYLAEVFEPYFGDGSSLGLHLEYVTEEEPLGTGGAIRNAAARLRSGPDEPVLVFNGDILTGLDIGALVRTHGTSGADVSLHLTKVSDPRAYGLVPTDETGRVLAFLEKPQTPEEIVTDQINAGAYVFRRSVIDTIPAGRPVSVERETFPGLLSAGAHLQGMVDSTYWLDLGTPAAFVRGSADLVLGRAPSPAVPGRCGDRLVLPTATVAPDAKLAGGTVVGEGAFVAEGARVFGSTILPGAVIEPGAVVTDSLIGSRARVGERSVLTGTVVGDGAVVGADNELREGVRVWCDARIPAGAVRFSSDQ
>NZ_CP010849.1|WP_078969169.1|3231533_3232964_-|N-acetylmuramoyl-L-alanine-amidase
MSRIGGMRGYLGSSIGVTCAAALALPLAPPAAAATARPAPPAEAPATGGAGRTGQPAPAAGRSYAPGGTQSLPLQPLPGDRAPGVAEQGLPARDVQRFSLVGVVWDEPDTELHGRVQVRTRATATGAWSPWQDLETHHADHGADPGTAERASGRVRGATAPLWVGESDGVQVRVRAEGGDGVRAGGVPAAGGLPTGLRLELVDPGADTAPAQGAPTAERSRSGAPGARPAEATAATASGAGPAPRGAAEIPALSRAETERELRAGALTGQQQTKPYIGPRPAIVTRSGWKADETLREKTFVYTKKVKAAFVHHTASGNNYTCAQAPSVIRSIYRYHVGSMGWRDIGYNFLVDKCGKIYEGRAGGVAKPVLGAHTLGFNTNSMGVAVIGTYSSTKPSSSAVKAIAQLAAWKLGLHGMNPKGKTSLTSGGGNLYPKGKSVRLNVISGHRDGFLTACPGGKLYGKLGTARSTAAKYQGR
>NZ_CP010849.1|WP_029384338.1|3233085_3233841_+|TIGR03089-family-protein
MNASDRTPADLLSSALAADPGRPLVTFYDDATGERVELSVATFANWVAKTANLLQDELSVEPGDRVTLLLPAHWQTAVWLLACASVGVVADVAGDPAAADVVVSGPDTLEAARACSGARIALALRPLGGRFPQPPEGFADYAVEVPGQGDRFVPYAPVDPEEPALIVAGREFSGAEVVERARAEATGLGLTGPGSRLLSGLPYDTWEGLNAGLYAPLATGGSVVLCRHLDRLGAEALDKRIEAERVTATAR

Crispr_ID: NZ_CP010849_12

• CRISPR_ID: NZ_CP010849_12
• CRISPR_location: 3284608-3284684
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_12

Consensus_repeat	Method
CGTCCTGCTGGGCGTACGGGTTC	CRISPRCasFinder

spacers of NZ_CP010849_12

>12.1|3284631|31|NZ_CP010849|CRISPRCasFinder
TGGGCGTACGGATTCTGCGCGTAGGGGGCGC

CRISPR arrays and Neighbor proteins around NZ_CP010849_12

CRISPR arrays

The CRISPR arrays of NZ_CP010849_12

>merge|NZ_CP010849|12|3284608-3284684|CRISPRCasFinder
CGTCCTGCTGGGCGTACGGGTTCTGGGCGTACGGATTCTGCGCGTAGGGGGCGCCGGCCTGCTGGGCGTACGGGTTC

>NZ_CP010849|12|11|3284608-3284684|CRISPRCasFinder
CGTCCTGCTGGGCGTACGGGTTC	TGGGCGTACGGATTCTGCGCGTAGGGGGCGC
CGGCCTGCTGGGCGTACGGGTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044382015.1|3296438_3296978_-|DUF501-domain-containing-protein	unknown	unknown	gnl|CDD|224424
NZ_CP010849.1|WP_044381998.1|3277954_3279343_-|cystathionine-beta-synthase	unknown	unknown	gnl|CDD|273464
NZ_CP010849.1|WP_044381994.1|3274930_3275515_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044382016.1|3297091_3297568_-|septum-formation-initiator-family-protein	unknown	unknown	gnl|CDD|368217
NZ_CP010849.1|WP_078969179.1|3294171_3295428_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP010849.1|WP_044382001.1|3280684_3281905_+|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|181146
NZ_CP010849.1|WP_029382944.1|3297670_3298951_-|phosphopyruvate-hydratase	unknown	unknown	gnl|CDD|234617
NZ_CP010849.1|WP_044382010.1|3287879_3290408_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223650
NZ_CP010849.1|WP_044382000.1|3279502_3280528_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238874
NZ_CP010849.1|WP_044382013.1|3292259_3293642_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224172
NZ_CP010849.1|WP_044381997.1|3277116_3277557_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044382009.1|3287022_3287820_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NZ_CP010849.1|WP_044382011.1|3290532_3291837_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|225139
NZ_CP010849.1|WP_029382933.1|3283441_3283669_+|DUF4287-domain-containing-protein	unknown	unknown	gnl|CDD|379478
NZ_CP010849.1|WP_044381995.1|3275626_3276469_-|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224651
NZ_CP010849.1|WP_044382008.1|3284961_3286137_-|4-hydroxybenzoate-3-monooxygenase	unknown	unknown	gnl|CDD|236198
NZ_CP010849.1|WP_078969178.1|3273050_3274571_+|diaminopimelate-decarboxylase	unknown	unknown	gnl|CDD|143505
NZ_CP010849.1|WP_044382005.1|3283028_3283310_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044382003.1|3282208_3282991_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044382014.1|3295500_3296442_-|Ppx/GppA-family-phosphatase	unknown	unknown	gnl|CDD|223326

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044382015.1|3296438_3296978_-|DUF501-domain-containing-protein	gnl|CDD|224424	COG1507, COG1507, Uncharacterized conserved protein [Function unknown].	6.75464e-63
NZ_CP010849.1|WP_044381998.1|3277954_3279343_-|cystathionine-beta-synthase	gnl|CDD|273464	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase. Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family].	0
NZ_CP010849.1|WP_078969179.1|3294171_3295428_+|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	1.5105e-33
NZ_CP010849.1|WP_044382001.1|3280684_3281905_+|acetyl-CoA-C-acetyltransferase	gnl|CDD|181146	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase.	0
NZ_CP010849.1|WP_029382944.1|3297670_3298951_-|phosphopyruvate-hydratase	gnl|CDD|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP010849.1|WP_044382010.1|3287879_3290408_+|ABC-transporter-permease	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	3.01515e-25
NZ_CP010849.1|WP_044382000.1|3279502_3280528_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238874	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it turn are loaded onto the acyl carrier protein FeeL. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	3.67187e-52
NZ_CP010849.1|WP_044382013.1|3292259_3293642_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	4.2671e-105
NZ_CP010849.1|WP_044382016.1|3297091_3297568_-|septum-formation-initiator-family-protein	gnl|CDD|368217	pfam04977, DivIC, Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.	3.09593e-12
NZ_CP010849.1|WP_044382009.1|3287022_3287820_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.40219e-109
NZ_CP010849.1|WP_044382011.1|3290532_3291837_-|methyltransferase-domain-containing-protein	gnl|CDD|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	6.1308e-116
NZ_CP010849.1|WP_029382933.1|3283441_3283669_+|DUF4287-domain-containing-protein	gnl|CDD|379478	pfam14117, DUF4287, Domain of unknown function (DUF4287). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 70 and 180 amino acids in length.	5.84531e-21
NZ_CP010849.1|WP_044381995.1|3275626_3276469_-|MurR/RpiR-family-transcriptional-regulator	gnl|CDD|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	6.51698e-31
NZ_CP010849.1|WP_044382008.1|3284961_3286137_-|4-hydroxybenzoate-3-monooxygenase	gnl|CDD|236198	PRK08243, PRK08243, 4-hydroxybenzoate 3-monooxygenase; Validated.	0
NZ_CP010849.1|WP_078969178.1|3273050_3274571_+|diaminopimelate-decarboxylase	gnl|CDD|143505	cd06836, PLPDE_III_ODC_DapDC_like_1, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Uncharacterized Proteins with similarity to Ornithine and Diaminopimelate Decarboxylases. This subfamily contains uncharacterized proteins with similarity to ornithine decarboxylase (ODC) and diaminopimelate decarboxylase (DapDC). ODC and DapDC are fold type III PLP-dependent enzymes that contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain, similar to bacterial alanine racemases. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. ODC participates in the formation of putrescine by catalyzing the decarboxylation of ornithine, the first step in polyamine biosynthesis. DapDC participates in the last step of lysine biosynthesis, the conversion of meso-2,6-diaminoheptanedioate to L-lysine. Proteins in this subfamily may function as PLP-dependent decarboxylases. Homodimer formation and the presence of the PLP cofactor may be required for catalytic activity.	0
NZ_CP010849.1|WP_044382014.1|3295500_3296442_-|Ppx/GppA-family-phosphatase	gnl|CDD|223326	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism].	1.33478e-88

Protein sequences

>NZ_CP010849.1|WP_029382933.1|3283441_3283669_+|DUF4287-domain-containing-protein
MSQVFSEETHRNLLARIPHCTGREISDWLRTVEEGPALRFEEKVSWLRHEHNLAYGHAKAIIHEYDLRRAARRLL
>NZ_CP010849.1|WP_044382005.1|3283028_3283310_-|hypothetical-protein
MDHFADRLRAAPQSRLQRGAAAEALALARELARRAQLAEEPGAQPREMPDAGMFAAADQITVAAHDLALVLGSEAEVAEAVRLVTEAQKRAGV
>NZ_CP010849.1|WP_044382003.1|3282208_3282991_+|hypothetical-protein
MSAMPIALLLTTAATGAVGVAVLRSIQVLRRQVAALHTELAESRAVAARGLVPAARTTADAAEIRAAVAEALAEERERELAEARAFWAAQEARDASDAPLLLGLPDSELYLPRQADFVGLEPVAEPGADADEPAGDSAELAAARRRHPSHPDFVPAPSPVVNDHERTAATLEELAAARVELTDVRPGPLGTLDVYVFADGTTLCMTPGHRETADRLAAALRAGDVPVLLGGSGVSGAYALTFACGGETVYVLADRVIASL
>NZ_CP010849.1|WP_044382001.1|3280684_3281905_+|acetyl-CoA-C-acetyltransferase
MPEAVIVSAARSPIGRAFKGSLKDLRPDDLTATIVQAALAKVPELDPRDIDDLMLGCGLPGGEQGSNLGRIVAVQMGMDHLPGCTVTRYCSSSLQTSRMALHAIKAGEGDVFISAGVETVSRYTKGNSDNLPDTHNPLFAQAEARTAAVAEQEGTTWHDPREDGLLPDPYIAMGQTAENLARLKGVTRQEMDEFGVRSQNLAEEAIKNGFWEREITPVTLPDGTVISKDDGPRPGVTMEGVAGLKPVFRPDGLVTAGNCCPLNDGAAALVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGPVEASRQALKRAGLTIDDIDLVEINEAFAAQVIPSYRDLGIPLEKLNVNGGAIAVGHPFGMTGARITTTLINSLQWHDKQFGLETMCVGGGQGMAMVIERLS
>NZ_CP010849.1|WP_044382000.1|3279502_3280528_+|SGNH/GDSL-hydrolase-family-protein
MTSMARARVARRIAAGAAYGGGGLGLAGAAAVGLLLAEMHLARRRVGIGTPPRVPNAEGLYGGTEHSAGQPPLRLVMLGDSTAAGQGVHRAGQTPGALLASGLAAVAERPVSLRSVALPGARSDDLDRQVSLVLADPARAPDICVIMVGANDVTHRMPATRSVRCLATAVRRLRTAGAEVVVGTCPDLGTIEPVRQPLRWLARRVSRQLAAAQTIGVVEQGGRTVSLGDLLGPEFAANPRELFGPDNYHPSAEGYATAAMAVLPTVCAALGLWPAEEERPDVSRREGFLPVARAAAEAASEAGTEVAAAMPAGPRGPWALLKRRRRRRVTEAEPAPSAQPS
>NZ_CP010849.1|WP_044381998.1|3277954_3279343_-|cystathionine-beta-synthase
MQFHDSMISLVGNTPLVRLNSVTKGIRATVLAKVEYFNPGGSVKDRIALRMIEAAEQSGELKPGGTIVEPTSGNTGVGLAIVAQQKGYKCVFVCPDKVSTDKINVLRAYGAEVVVCPTAVDPEHPDSYYNVSDRLVRETPGAWKPDQYSNPNNPLSHYHSTGPELWEQTEGRITHFVAGVGTGGTISGTGRYLKEASDGRVKVIGADPEGSVYSGGSGRPYLVEGVGEDFWPTAYDRTVADEIVAVSDKDSFQMTRRLAKEEGLLVGGSCGMAVVAALRVAERLTEDDVVVVLLPDSGRGYLSKIFNDEWMADYGFLDDAGPSARVGDVLEHKEGGSIPSLVHMHPDETVGQAIDVLREYGVSQMPIVKPGAGHPDVMAAEVVGSVVERELLDALFTQRAALDDPLERHMSAPLPQVGSGEPVEDLMTVLGTADAAIVLVEGKPTGVVSRQDLLAFLAEGGK
>NZ_CP010849.1|WP_044381997.1|3277116_3277557_+|hypothetical-protein
MYAIRSYYARESDLKKDLDATLRARGELGEEYEAALIESFLEKVDQRIDDAVERRVRRQLAERQMAAARDDRSAAPTDSWGERFGFGIVSLVLAIPLSAIGGGTGRLPGLLAAWAGIVGVNVVQAVRTDPDIFRRRKPSPDDDREE
>NZ_CP010849.1|WP_044381995.1|3275626_3276469_-|MurR/RpiR-family-transcriptional-regulator
MSVTDSPAARLQALFEGHRLTPTQRRIAHSMVRRAADVPFLSSVELAELAGVSQPSVTRFAVALGFDGYPALRRHLREVAPAEPAAEAGTPNEYQQAVEAEIENLRHLAEVLADPRPVREAGRVLAASRPLPVLGLRAAASQAYGFAYFAAKVHPDVRPLHEGGTMLQDRIDGAVRAGATALLCFALPRHPREVVDTLAYAKEAGLTVVTVADSAFAPVAKVSDLLLPAAVGTGLVFDTACAPMLLGRVLLEAMCDDLPDAQARLEEFDAKAAARGLFVE
>NZ_CP010849.1|WP_044381994.1|3274930_3275515_-|hypothetical-protein
MARGGHGLARVAVVVRAGAAPLWWLGVLAAGVGVCVPGLTGRRIGVTAGAALFVVALAVVVYARRKRYAALARSAARAGKHDVLQDRAVTARNWRHGHRWWLLLAFLAAVGSAFAAPAAGGMLLAGCGAGLWLKAAWVGRLERDADVLLWVRVDWLGRNAGGAVGKAVKGYRSTGIAAGDAAPGGAPRKMAALV
>NZ_CP010849.1|WP_078969178.1|3273050_3274571_+|diaminopimelate-decarboxylase
MNRASQYGGAPTRTCRGCLAGRGGAGSAGTGDGEGVDTNIGHLDGTDGTEGTGAERAARRDAAVRAAVERGLLGPGAPLAGLLDVVGIRESAAALRAAFDAVVAPGTPVLHAFAVKAAPLVPVVRLLHALGLGAEVASPGELALARAAGVPPEHTVLDSPAKTPQELREALELGIAVNADNPQELERIDGLMRTTGSRSPLGVRVNPQVGGGSIEALSTATATSKFGVALRDEGAREWVVRAFLDRPWLTRLHTHTGSQGIPPALMAEGVAAAYALAEEINERAGRRQVDTVDIGGGLPVNFTSDETSPTYAAYARELRAAVPGLFDGRYGLVTEFGRSLLAKHGTLVARVEYAKSAGGRPVAVTHAGVQVATRTVYAPGAWPLRIAAYDAEGRPKDGPDVVQDVAGPACFAGDLLATGRALPLLRQGDYAAALDTGAYYFAHHYGYNSLARPGVYGFAPDGEGGVAFAVVRDPQPVQEIVAEAGGAHADALTSALAPRETRPARG
>NZ_CP010849.1|WP_044382008.1|3284961_3286137_-|4-hydroxybenzoate-3-monooxygenase
MRTTVGIIGAGPAGLLLARLLHNAGIDSVVLESRDRAYVERRQRAGILEQGTVDVLRAAGAGERMDREGLRHDGIELRFDRTRHRVDFPALTGGKSVMVYAQTEVCKDLIALQIEEGGPLLFEAEALAVEGADTDTPRIRFRHQGAEDVLECDYVVGCDGFWGVARRAIPAELSRTFERTYPFGWLGILADAAPSHDELVYARHDRGFALLSMRSPSVSRLYLQVPEGTDAEAWSDEEIWDELERRFETADDWRLERGPITQKSVTPMRSFVHEPMRHGRLFLAGDAAHIVPPTGAKGLNLAVGDVVTFARALVHRRETGSAELLDAYSATCLRRVWQAERFSYDMTTLLHRAPDATPFDDRLQVARLRRIASSRAAETDLAEAYTGFPVG
>NZ_CP010849.1|WP_044382009.1|3287022_3287820_+|ABC-transporter-ATP-binding-protein
MTTASSPGLRPGGPPAGRSTAVAARATELSKIYGAGETQVVALDRVSVEFRQAEFTAIMGPSGSGKSTLMHCVAGLDTFSSGSVRLGDTELGSLKDKQLTTLRRDKIGFIFQAFNLLPTLTALENITLPMDIAGRKPDRQWLDTVIEMVGLSGRLSHRPSQLSGGQQQRVAVARALASKPEIIFGDEPTGNLDSRSGAEVLGFLRNSVRELGQTVVMVTHDPVAAAYADRVVFLADGRIVDELYGPTADAVLDRMKRFDAKGRTS
>NZ_CP010849.1|WP_044382010.1|3287879_3290408_+|ABC-transporter-permease
MFRTALRNVLAHKARLLMTVLAVMLGVAFVSGTLVFTNTISGALQDSSAKGFDHVDVAVQPKFQDAEGDRVGKAPELTQAVLDRSAKVPGAASAVGVVGGFTAVADRDGKLIGNGFSTLGGNYWGTEDPRYPLVSGHAPKGPGEVLIDSETAERTGYRVGDTVRLSVDGPVLTPTVTGVFTTDDGNVAAGGSLTLFDTATAQKLFGKPGTYDEIAVEAKPGVTQAALKDRLDRALPAGLVETTTGEQLAEDQAEAIASSMSGMRQGLLVFAGIALFVGTFIIANTFTMLVAQRTKELALLRAVGASRRQITRSVLVEAFVVGLAAAVAGLAAGIGIGAGLRALMGSLDATVPNGPLVVSPGTVVSAFAVGVLVTMLAAWLPGRRAAKIPPVAAMSSVHAKASAKSLVLRNTLGALFSAAGVAVVLAATTMGGSDGQAPMGLGAVLLITGVFILTPLLSRPLIAAASPVLRLFGVAGKLARQNSVRNPRRTAATASALMIGLTLITGMTVMAGSLQKSIDKMAASAIEADYVVSMANGNLLSTDVEEKLKRAGDVTATSPLRNSPSRIGGQTEYLTGVDGSAIGELTELKVADGSFTVDGTRVAVDDTTAEQHGWKAGSAFTVAYEDGRKQKLTVAGVYEGNEMMRGIMIDTATLTPHQSDPADMQVMVKTAGGASDAAKDRLEKALGSNPAIKVQDKKDLSREIAQMFTLMLNMLYGLLAMAVIVAVLGVVNTLAMSVFERSQEIGMLRAIGLDRRGIKRMVRLESLVISLFGGVLGIGLGVFFGWAAGRLLGASMPTYELVLPWGRMAVFLLLAAAVGVLAALWPARRAARLNTLQAIKAE
>NZ_CP010849.1|WP_044382011.1|3290532_3291837_-|methyltransferase-domain-containing-protein
MADAAPRLKGLVEQVLGTPLPVRIRAWDGSQAGPPGAPVLVVRDRRALRRLLWKPGELGLARAWVAGELEIEGDLYAALDLLSGLIWERGEDARSLGQALRDPEVRAAVRGLLRLAGPVPPPAPPREEVRRVRGHLHTRRTDRRAISHHYDVGNDFYELVLGPSMVYSCAYWRAPEAEGGTLEEAQRDKLELVCRKLGLKPGQRLLDVGCGWGSMAIHAAREHGVSVVGVTLSQEQAAYARKRVADEGLTDRVEIRVQDYRDVADGPYDAISSIGMAEHVGADRYLEYAQDLYALLKPGGRLLNHQIARRPERDESAYRVDEFIDAYVFPDGELAPIGTTVTQLERAGFEVRDVESIREHYALTLRRWVANLETHWERAVRLTSPGRARVWRLYMAASALSFERNRIGVNQVLAVKTPEPGGSGMPLRSRTWNG
>NZ_CP010849.1|WP_044382013.1|3292259_3293642_-|NAD(P)/FAD-dependent-oxidoreductase
MSTTERPRILVVGGGYVGLYAARRILKKMRYGEATVTVVDPRSYMTYQPFLPEAAAGNISPRHVVVPLRRVLPKAEVLTGRVTTIDQDRKVATIAPLVGEAYELPFDYLVIAMGAVSRTFPIPGLAEQGIGMKGIEEAIGLRNHVLEQLDKADSTTDEEIRRKALTFVFIGGGFAGAETVGEVEDMVRDAAKYYKNVSREDMRFILVDAADKILPEVGPKLGTYGKEHLEGRGVEVYLSTSMESCVDGHVVLKNGLEVDSNTIVWTAGVKPNPVLSRFGLPLGPRGHVDCEPTLQVKGMDYVWAAGDNAQVPDLVGRKNGNPNAWCPPNAQHALRQARVLGDNVLSGMRGFPQKEYSHANKGAVAGLGLHKGVAMIVMGKMKIKLKGRLAWYMHRGYHGMAMPTWNRKIRVFADWTLGMFLKREVVSLGAIESPREEFYEAAKPAPAPVAAKTEEKAKAS
>NZ_CP010849.1|WP_078969179.1|3294171_3295428_+|serine/threonine-protein-phosphatase
MSPHRRTTGLVSHAAESETLPLPRWARWLPLALVGVALAVDLPTPGAFSGDVFLVLSAMTAAYVHTLRPVILMALLNSAAGLLLLFAEHLESDGGHAVVDYFALLLLAWASVPLCLLRMWLDRRLQGARRTAESAQRAVLPPVRAWLGTTWIAVRYEAASDAAAVGGDLYAAEETPYGVRLLIGDVRGKGTDAIPGVAALVGSFREAAHHTETLPLLARHLDEAVARHVRDLAAVRVQEGTRGEQFVTAAIAEFPPGGGEVRLISRGHCPAYLAGAEGVRMWKPAEPGLPLGLGELDPGPWEYESRPFAPGDLLLMCTDGLLEARDAGGSFFTPEEGLCGCWRQGPPAVVDTVARLVHRHAGGVLADDLVLMAATVTETPYRPPRAMTPHGPGGTGDSGGDGEGCATPPDPTGPSAEH
>NZ_CP010849.1|WP_044382014.1|3295500_3296442_-|Ppx/GppA-family-phosphatase
MTRVAAVDCGTNSIRLLVADADPATGELVELDRRMTIVRLGQGVDRTGRLAPEALERTFAACREYAGIIKAHGAERLRFVATSASRDASNRDDFVRGVLDILGVEPEVISGDQEAEFSFTGATKELTGRTDLHRPFLVVDIGGGSTEFVVGDDHVRAARSVDVGCVRMTERHLLRDGAVTDPPTEEQVAAMRADIEAALDLAERTVPLREARTLVGLAGSVTTVSAIAQELPAYDSTAIHHSRVTLDRVREITGHLLRSTHAERAAIPSLHPGRVDVIGAGALVLLSIMERIGAEEVVVSEHDILDGIAWSVA
>NZ_CP010849.1|WP_044382015.1|3296438_3296978_-|DUF501-domain-containing-protein
METPPPPTPRTEPTDADVAAFKQQLGRPPRGLRAIAHRCPCGQPDVVETAPRLPDGTPFPTLYYLTCPRANSAIGTLEAEGVMKEMTERLATDPELAAAYRAAHEDYIRRRDEIEELKNFPSAGGMPDRVKCLHVLVAHSLAAGPGVNPLGDEALAMLPEWWRKGPCVTASESCGEDEK
>NZ_CP010849.1|WP_044382016.1|3297091_3297568_-|septum-formation-initiator-family-protein
MAVKDRDRFSTATRIRLLGEQTAARVYRSQTKRQARRSRLTGRAALLAMVVCSLVVALAYPIRQYVAQRGEIADLRRQKQQTQERVERLRDEKARWQDDAYAEQQIRKRLHYVMPGETGYIVVDPGAGKQSRTDLGAADRPWYRNIWDEVDTSDASGG
>NZ_CP010849.1|WP_029382944.1|3297670_3298951_-|phosphopyruvate-hydratase
MPSIDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGAFEAIELRDGDTNRYQGKGVEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKGSLGANAILGVSLAVAHAASEASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFSEALRWGAEVYHTLKKVLKNRGLSTGLGDEGGFAPNLGSNREALDLILEAVKEAGYTPGEQIALALDVAASEFYKDGVYVFEGKERTAAEMTEYYAELVEAYPLVSIEDPLFEDDWEGWKTITAKLGDKVQLVGDDLFVTNPERLAKGIEEGAANALLVKVNQIGSLTETLDAVELAQRNGYKCMMSHRSGETEDVTIADLAVATNCGQIKTGAPARSERVAKYNQLLRIEEILDDAAVYAGRSAFPRFKG

Crispr_ID: NZ_CP010849_13

• CRISPR_ID: NZ_CP010849_13
• CRISPR_location: 3327602-3327733
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3

Consensus repeat of NZ_CP010849_13

Consensus_repeat	Method
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA	CRISPRCasFinder

spacers of NZ_CP010849_13

>13.1|3327644|48|NZ_CP010849|CRISPRCasFinder
GTCGGCGTCGTCGGCGCGGTTGCCGTCGGGTGGGAACGGCCTGGTGGG

CRISPR arrays and Neighbor proteins around NZ_CP010849_13

CRISPR arrays

The CRISPR arrays of NZ_CP010849_13

>merge|NZ_CP010849|13|3327602-3327733|CRISPRCasFinder
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAGTCGGCGTCGTCGGCGCGGTTGCCGTCGGGTGGGAACGGCCTGGTGGGCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA

>NZ_CP010849|13|12|3327602-3327733|CRISPRCasFinder
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA	GTCGGCGTCGTCGGCGCGGTTGCCGTCGGGTGGGAACGGCCTGGTGGG
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044382053.1|3330533_3331982_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl|CDD|184641
NZ_CP010849.1|WP_044382057.1|3333992_3334595_+|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|235457
NZ_CP010849.1|WP_044382031.1|3310049_3310730_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044382034.1|3311689_3311872_+|antitoxin	unknown	unknown	gnl|CDD|379416
NZ_CP010849.1|WP_044382058.1|3335282_3336062_+|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl|CDD|237030
NZ_CP010849.1|WP_044382040.1|3319810_3321304_+|MFS-transporter	unknown	unknown	gnl|CDD|341045
NZ_CP010849.1|WP_044382051.1|3329559_3330312_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044382045.1|3325014_3326058_-|cell-wall-assembly-protein	unknown	unknown	gnl|CDD|379604
NZ_CP010849.1|WP_044382035.1|3311983_3315517_-|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl|CDD|224118
NZ_CP010849.1|WP_044382059.1|3336146_3338888_-|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl|CDD|366019
NZ_CP010849.1|WP_078969182.1|3322490_3325007_-|hypothetical-protein	unknown	unknown	gnl|CDD|373070
NZ_CP010849.1|WP_044382060.1|3339179_3340190_+|acyl-CoA-desaturase	unknown	unknown	gnl|CDD|224316
NZ_CP010849.1|WP_044387923.1|3334659_3335151_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044382042.1|3321421_3322306_-|cellulose-binding-protein	unknown	unknown	gnl|CDD|173412
NZ_CP010849.1|WP_078969181.1|3310811_3311645_-|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP010849.1|WP_044382037.1|3315845_3318410_-|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|226957
NZ_CP010849.1|WP_044382054.1|3332117_3333092_+|ribose-phosphate-diphosphokinase	unknown	unknown	gnl|CDD|179535
NZ_CP010849.1|WP_044382055.1|3333307_3333895_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl|CDD|235534
NZ_CP010849.1|WP_044382039.1|3318406_3319195_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP010849.1|WP_044382049.1|3328082_3329393_-|histidine-kinase	unknown	unknown	gnl|CDD|226951

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP010849.1|WP_044382035.1|3311983_3315517_-|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	1.4e-11	38.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044382053.1|3330533_3331982_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl|CDD|184641	PRK14352, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_CP010849.1|WP_044382057.1|3333992_3334595_+|aminoacyl-tRNA-hydrolase	gnl|CDD|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	1.9934e-93
NZ_CP010849.1|WP_044382034.1|3311689_3311872_+|antitoxin	gnl|CDD|379416	pfam14013, MT0933_antitox, MT0933-like antitoxin protein. This family of proteins contains the MT0933 protein, which has been identified as an antitoxin to /protein MT0934. This family of proteins is found in bacteria. Proteins in this family are typically between 61 and 90 amino acids in length.	1.50606e-06
NZ_CP010849.1|WP_044382058.1|3335282_3336062_+|LPXTG-cell-wall-anchor-domain-containing-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.06372e-05
NZ_CP010849.1|WP_044382040.1|3319810_3321304_+|MFS-transporter	gnl|CDD|341045	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including various Saccharomyces cerevisiae proteins such as azole resistance protein 1 (Azr1p), vacuolar basic amino acid transporter 1 (Vba1p), vacuolar basic amino acid transporter 5 (Vba5p), and Sge1p (also known as Nor1p, 10-N-nonyl acridine orange resistance protein, and crystal violet resistance protein). MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.353e-61
NZ_CP010849.1|WP_044382045.1|3325014_3326058_-|cell-wall-assembly-protein	gnl|CDD|379604	pfam14414, WHH, A nuclease of the HNH/ENDO VII superfamily with conserved WHH. WHH is a predicted nuclease of the HNH/ENDO VII superfamily of the treble clef fold. The name is derived from the conserved motif WHH. It is found in bacterial polymorphic toxin systems and functions as a toxin module. WHH is the shortest version of HNH nuclease families. Like AHH and LHH, the WHH nuclease contains 4 conserved histidines of which the first one is predicted to bind a metal-ion and other three ones are involved in activation of water molecule for hydrolysis.	2.52738e-12
NZ_CP010849.1|WP_044382035.1|3311983_3315517_-|transcription-repair-coupling-factor	gnl|CDD|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_CP010849.1|WP_044382059.1|3336146_3338888_-|phosphoenolpyruvate-carboxylase	gnl|CDD|366019	pfam00311, PEPcase, Phosphoenolpyruvate carboxylase.	0
NZ_CP010849.1|WP_078969182.1|3322490_3325007_-|hypothetical-protein	gnl|CDD|373070	pfam14440, XOO_2897-deam, Xanthomonas XOO_2897-like deaminase. A member of the nucleic acid/nucleotide deaminase superfamily prototyped by Xanthomonas XOO_2897. Members of this family are present in a wide phyletic range of bacteria and are predicted to function as toxins in bacterial polymorphic toxin systems. The Xanthomonas XOO_2897 lack an immunity protein and is predicted to be deployed against its eukaryotic host.	1.79687e-33
NZ_CP010849.1|WP_044382060.1|3339179_3340190_+|acyl-CoA-desaturase	gnl|CDD|224316	COG1398, OLE1, Fatty-acid desaturase [Lipid metabolism].	1.05828e-68
NZ_CP010849.1|WP_044382042.1|3321421_3322306_-|cellulose-binding-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	5.04989e-05
NZ_CP010849.1|WP_078969181.1|3310811_3311645_-|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	7.08592e-33
NZ_CP010849.1|WP_044382037.1|3315845_3318410_-|FtsX-like-permease-family-protein	gnl|CDD|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	6.64183e-27
NZ_CP010849.1|WP_044382054.1|3332117_3333092_+|ribose-phosphate-diphosphokinase	gnl|CDD|179535	PRK03092, PRK03092, ribose-phosphate diphosphokinase.	0
NZ_CP010849.1|WP_044382055.1|3333307_3333895_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl|CDD|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.9164e-67
NZ_CP010849.1|WP_044382039.1|3318406_3319195_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	6.2804e-111
NZ_CP010849.1|WP_044382049.1|3328082_3329393_-|histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	5.30127e-34

Protein sequences

>NZ_CP010849.1|WP_044382045.1|3325014_3326058_-|cell-wall-assembly-protein
MTTGRLGLGAAPGSQAGGQAVPPNAAYAGQVVHFPDPVRAARHPRGVRVDERGYPDFSPYARAAVEIADPPAGFGVDELRLTDYVSANAALSAAGHELWDTVPAVATPHGWTWHHVAGTRRLELVPVEVKALLRHHGGIATAAVDQGKRGTRPLQETRPAHFGLPKSGVAVTESQVQGVEEDLGYRLPGAYRSFLKAAGGCAPVGTALDAELGLLVDQPFFTVREEAAVNDLVYVNKCLRDHLTKDYLGVAFVQGGLLAVKVKGDRVGSVWFCAYDDARDVDPAWSPAERVERLLLPCGEDFDAFLTRLAGSPPELETVANLMVDGGFARVVSPTGPAAASAASAGE
>NZ_CP010849.1|WP_078969182.1|3322490_3325007_-|hypothetical-protein
MVTFAQAQERAEEWINGDVPSSGHREVRVREFELGFVVWPEDPADGPRSDGGAQRLVIARDSGEATLWPALPVGEVIRRYEEEYGRPDPVDEPAPVPAARVDLNQTSFLLTPPEWLQEAADRMGGPERRGAGAGDGSGAGVPSAAARGASGASEGPAGGAGAPGVPVGATPWTGTDTSADAGEDRSVPLPDTVSAPPLSGADDDPEPGVPPQAPPRPPAGPGTPPYGSGPGAGAPTPPPPGAMPPGAPGAAPPPVPPVPPVLSVPSGAPLPQEAPMPLPQERLGGPGGAGGAGSGAAGAGAAAPGVVGTPEAAGTAGVAGVPHPAAPPGGSGVPGAPVPQPPVPPGAPRPPGASQFPGVPGAPGVPGVPGMPASTAPAAPPAGGPGAPAVGGPGAPGPGVPPVGGPGVPPPSAPGVPLPPAAPGTPPPVQGPGAPVPPVPGAPLPPPGPGTSAPPHPGAPFPPPAPGASPVPPVPGAPAGHGAPAPVPPGAVPPPGGPVPGPPPAYGYPPQPTGLPTVGPGYQAVLRYRAQDGSEQQLIRRSAPGMPHPEWQIFHELRAMNVPPDQVLELHTELESCELPGAYCARMIREQWPQARLASIAPYGTDHASRQQGMRQLLAHQKELHQVADGPARPAPVRAPLPPVQALPPVPPEAVAQELAAAFGPGLFRFEQAAVDRQGVPPVVAHTLVVAGLPVDMGPFFWAQAQPGRPVPTLAELAAERGVRPASDAGSYLVVGSDFGKAICVQYGTANIVAVPVEAGPGGAPVPPQFVNTGLPEFARCLALLGRMWRLRYGLNQEQAGRWTVDFQAQLAALDPAALGSPESWWSVLLEQMWDGLL
>NZ_CP010849.1|WP_044382042.1|3321421_3322306_-|cellulose-binding-protein
MSSASGSPHGFVAVRGRGYRPEQVDARVAALSAERDAAWERAARLTVLAREMEAETTRLREAVERLAPQTYEALGGRARRVFRLVREEAAALVEGARRAGERAMEEARAHANGVRKDAQAYADAVRAEADERARQRLLAARAEAEGIRVAARRAVKESRREGLAVLREARRSASETLAGQSREHAERWAGEERAEAARAAALNRHRAELLKRAEDALAEAERELAGAREAARRRQEEARARAAEVIAEARVHEERVASETERVLHEHQERWDVVRAEMDQARSRLEALSARVAR
>NZ_CP010849.1|WP_044382040.1|3319810_3321304_+|MFS-transporter
MDSTRPAIRDTERPTAHRRGAVVAALMLAMALAALDSTIVSTAVPQIVGDLGGFSVFSWLFSGYLLAVTVTLPVYGKLSDTFGRKPVLVAGAALFLLGSLLCALAWNMAALIAFRVVQGLGGGALQGTVQTLAADLYPLEERPRIQARLSTVWAVSAVAGPGLGGVLAAYADWRWIFLVNLPIGAVALWLIVRHLREPQREPSAARPRVDWAGALAVFACGGALLTALVQGGVAWPWLSPPSLALFGAGLLLLVAVVVIERRAAEPIIPGWVWRRRTIAAVNLALGALGLLMVAPTVFLPTYAQSVLGLAPVAAGFVLSVWTLSWPVSAALSQHVYRRIGFRNTAMLGIGTATLILFAFPFLPYPGEPWQPALLMLLLGAALGLFQLPLIVGVQSTVVWSERGTATASVLFCRQTGQTAGAAVFGAIANGVLAARLGGSGDLDSVTRALDAGTAPEATRRAIADAVHAVYLGAAGAAALAFLVLLVLAPRVFPVLKD
>NZ_CP010849.1|WP_044382039.1|3318406_3319195_-|ABC-transporter-ATP-binding-protein
MTSAVTIPRHGSTGGRTAVAARARQVVKAYGAGETRVVALDHVDVDIARGQFTAIMGPSGSGKSTLMHCLAGLDTVTSGHIHLDETEITGLKDKKLTQLRRDRIGFIFQAFNLLPTLNALENITLPMDIAGRKPDREWLARVVDTVGLAGRLKHRPTQLSGGQQQRVAVARALAARPEIIFGDEPTGNLDSRAGAEVLGFLRRSVDELGQTIVMVTHDPVAASYADRVLYLADGRIVDEMYQPTAEQVLDRMKDFDARGRTS
>NZ_CP010849.1|WP_044382037.1|3315845_3318410_-|FtsX-like-permease-family-protein
MTVLKTSLRNFLAHKGRMALSAVAVLLSVAFVSGTLVFTDTMNTTFDKLFASTSSDVTVTPKDAKDGETPQSGVPQSLPASVLERARAAEGVKSAEGGVSATNVTVVDSRNDNVGASNGAPTIAGNWTKNELKSMEITSGHAPRGPTEVMVDADTADKHGLNLGDELRTIAQSGDIRARIVGIAAFQVTNPGAAIVYFDTATAQRELLGGTGRYTHILVTAAAGVSDAQVKENVTRALGGTYKIQTAAETADENRKEVGEFLDVIKYAMLGFAGIAFLVGIFLIINTFSMLVAQRTREIGLMRAIGSSRRQVNRSVLVEALLLGVVGSVLGVAAGVGIAIGLMEVMSAAGMNLSTDDLTVKATTPVAGVILGVVVTVLAAYLPARRAGKISPMAALRDAGTPADGKAGRIRAAVGLVLTGAGALALYTAGTADKAGDGALMLGAGVVLSLIGFVVIGPLLAGSVVRVIGAVLLRAFGPVGRMAERNALRNPRRTGATGAALMIGLALVACLSVVGSSMVASATGELDKSVGADFIVQGSQRIVPQAERAMQKTPHLEHVTRYKTLDATLTSPDGAKDDSGVTAADPTYAEDLRRPTTAGSLADAYAADAMSVGSDYAAEHGVRVGDTLTVAFEGGETAKLKVAAITDDDTAIDQGARYISITTMRKYLPADKIPPNTILFAKARDGQEEQAYAALKKALDPYPQYQVRDQTDYKQELKDQIGQLLNLVYGLLALAIIVAVLGVVNTLALSVVERTREIGLMRAIGLSRRQLRRMIRLESVVIALFGALLGLGLGMGWGTTAQKLLALEGLNVLDIPWPTIIGVFIGSAFVGLFAALIPAFRAGRMNVLNAIATE
>NZ_CP010849.1|WP_044382035.1|3311983_3315517_-|transcription-repair-coupling-factor
MSLHGLLDAVVKDAALAEAITAAADGNRPHVDLVGPPAARPFAVAALARETGRPVLAVTATGREAEDLAAALRSLLPPEGVVEYPSWETLPHERLSPRSDTVGRRLAVLRRLAHPRPDDPETGPVSVVVAPVRSVLQPQVKGLGDLEPVALRTGQSADLNDIVEALAAAAYARVELVEKRGEFAVRGGILDVFPPTEEHPLRIEFWGDDVEEIRYFKVADQRSLEVAEHGLWAPPCRELLLTDEVRERARALAEDHPELGELLGKIAEGIAVEGMESLAPVLVDDMELLLDVLPKGAMALVCDPERVRTRAADLVATSQEFLQASWAATAGGGEAPIDVDAASLWSLADVRERARELDMMWWSVSPFAADEELGTDTLKLGMHAPDTYRGDTAKALADTKGWLADGWRTVFVTEGHGPAARTVEVLGGEGIAARLDADLGEMSPSVVHVACGCIDHGFVDPVLKLAVLTETDLTGQKAAGRDGTRMPARRRKTIDPLTLEPGDYIVHEQHGVGRYIEMVQRTVQGATREYLVVEYAPAKRGQPGDRLYIPTDQLEQITKYVGGEAPTLHRLGGADWTKTKARAKKAVKEIAADLIKLYSARMAAPGHSFAPDTPWQRELEDAFPYAETPDQLTTIAEVKEDMEKSVPMDRLICGDVGYGKTEIAVRAAFKAVQDGKQVAVLVPTTLLVQQHYGTFSERYAQFPVNVRALSRFQTETEAKAVLEGLRDGSVDVVIGTHRLFSSDTKFKDLGLVIVDEEQRFGVEHKEQLKKLRANVDVLTMSATPIPRTLEMAVTGIREMSTITTPPEERHPVLTFVGPYEEKQIGAAIRRELLREGQVFYIHNRVESIDRAAARLRDIVPEARIATAHGQMSEQALEQVVVDFWEKKFDVLVSTTIVESGIDISNANTLIVERGDTFGLSQLHQLRGRVGRGRERGYAYFLYPPEKPLTETAHERLATIAQHTEMGAGMYVAMKDLEIRGAGNLLGGEQSGHIAGVGFDLYMRMVGEAVADYRRQLETGEVEEEQPLEVKIELPVDAHVPHDYAPGERLRLQAYRAIASANTEEDIKAVREELVDRYGKLPEPVENLLLVAGLRMLARACGVGEIVLQGANIRFAPVELRESQELRLKRLYPGSILKPTAHQVLVPRPKTAKVGGKPLVGRELLAWVGEFLASVLDS
>NZ_CP010849.1|WP_044382034.1|3311689_3311872_+|antitoxin
MGIFDKLKNKMSPDKTKGMSDAAEKQVNERTGHKYEDQVDTAQQKAEERFGVDRDRPDRP
>NZ_CP010849.1|WP_078969181.1|3310811_3311645_-|HNH-endonuclease
MVKECRICGDVVWTSRRLPLRQATVPDGADRRAGEGGRTVRWRRGGAVTAVAVALLAVAGCTEGTTGDGGPEGTARAGTALAAVDSLTVKGRAPRTGYDRDKFGTPWADTDANRCDTRDDILRRDLEDVEFSDGRCKVASGVLEPDPYTGRRIAFTRGRSRVDIDHVVALSDAWQKGAGQWDAAKRIALANDPLNLLAVDASTNRAKGDGDTATWLPPDKSYRCPYVAAQVAVKKKYGLWVTAAEKAAMKRVLTRCPDQPLPTGGNPTRAPGRFHAD
>NZ_CP010849.1|WP_044382031.1|3310049_3310730_+|hypothetical-protein
MGMKGKIALGAVVGIAVIGAVSANAGGGDGGGSETGKGASASAQGKSGGEKDAGKAAGEKKVAFEGDGDFQVGTDVEPGTYRTTGNADGMCYWERAKDASGELDSLLANDNVSGTGYVTVKPTDKVFKSSGCGDWEAVDPRAKGSPAATMAGDGGMFRVGADIAPGTYKSTGNTDDSCYWERAKDAEHSIDSIIANDNVSGTAVVRISSSDAYFKTSGCQDWKKTG
>NZ_CP010849.1|WP_044382049.1|3328082_3329393_-|histidine-kinase
MTTTGEDHVPARGGPWWWARRRGAALDAALAAVSALECAVEGVPFARDAGIPVAAGVVFGLLAGSVLLVRRQWPIAVVLVAIAITPAQMGSLMAIVGLYTLAASELPRRIIGALAGMSLLGTLIVMFVRLKQDMARGDLDLGDWFVPFASITASLGLTAPPVLLGMYVGARRRLMESLRERADSLERELQLLAERAEERAEWARSEERTRIAREMHDVVAHRVSLMVVHAAALQAVARKDPEKAVRNAALVGDMGRQALTELREMLGVLRSGGSERRERAVSAAPLAAVGAAAAAAASRAAAEEGGPCLAELEELVGQSAAAGMAVDLSVEGEPRSCAAEVEQTAFRVVQEALTNVHKHAAGAKTRVRLAYRASEIAMQVENGPPPEGSSASSARLPSGGNGLVGMKERVTALGGVFVSGPTEAGGFRVSAVIPES
>NZ_CP010849.1|WP_044382051.1|3329559_3330312_+|hypothetical-protein
MAHPPGTPTDFDALRDRAPSRRPNAKDDLRERARELRLKGWTYDRIEAELGCSRSSVSLWVRDLPRPQPRYTPEEQQALMQAGLARLRDARNEERKRIKNDAAQEIGELTDRELFMTGLALYWAEGSKSKPYDRRERAVFVNSDPGVIQVYLAWLDLLDVSRDRLGFRVLIHESADVDAACRYWAQLAGVEVSAFAKPTLKRHNPKTVRKNTGGAYHGCLVVTAARSADLYNRIEGWWNGIVTHAQARLR
>NZ_CP010849.1|WP_044382053.1|3330533_3331982_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSANRPAAVVVLAAGEGTRMKSATPKVLHDICGRSLVGHVLAAAGELEPENLVVVVGHAREKVTAHLAEVAPDVRTAVQAQQNGTGHAVRMALEELGGAVDGTVVVVCGDTPLLTAETLGSLASTHAGDGNAVTVLTAEVPDATGYGRIVRDEATGAVTAIVEHKDATDAQRAIREINSGVFAFDGRLLADALGKVRTDNSQGEEYLTDVLGILREAGHRVGACVAGDHREIAGINNRVQLAEARRILNDRLLTRAMLSGVTVVDPATTWVDVTVTFERDVLVHPGTQLHGTTHLAEGCEVGPNARLTDTRVGAGARVDNTVALAAEIGPEATVGPYAYLRPGTRLGAKGKIGTYVETKNATIGEGTKVPHLSYVGDATIGEYTNIGAASVFVNYDGQDKHHTTVGSHCRTGSDNMFVAPVTIGDGAYTAAGSVITKDVPPGSLAVARGQQRNIEGWVARKRPGSAAAKAAEAASREPDGEG
>NZ_CP010849.1|WP_044382054.1|3332117_3333092_+|ribose-phosphate-diphosphokinase
MTGIKTTGEKKMMFFSGRAHPELAEEVAHELGVGVVPTKAFDFANGEIYVRYQESARGADCFLIQSHTAPINKWIMEQLIMIDALKRASARSITVIVPFYGYARQDKKHRGREPISARLIADLMKTAGADRILAVDLHTDQIQGFFDGPVDHLFALPLLADYVGAKVDRQKLTVVSPDAGRVRVADRWCDRLGAPLAIVHKRRDKDVANQVTVHEVVGDVKGRICVLVDDMIDTGGTICAAADALFAHGAEDVIVTATHGVLSGPAADRLKNSKVSEFVFTNTLPTPNELELDKITVLSIAPTIARAVREVFEDGSVTSLFDEQ
>NZ_CP010849.1|WP_044382055.1|3333307_3333895_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MSEVKIAAETRTEFGKGAARRIRRDNKVPGVLYGHGSDPLHLTFPGHELLLALRTPNVLIALDIDGKSNELAIPKAVQRDPLKGFLEHVDLQLVQRGETVTVEIVVQTEGELAPGGNLLEHLLDTVTVEAEATHIPESVTVSIEGLSAGDTIHAKDIPLPKGTKLAVDGETPVLQIVNSQVEASAEGEGEEAAEA
>NZ_CP010849.1|WP_044382057.1|3333992_3334595_+|aminoacyl-tRNA-hydrolase
MDVTTDAGAPWLIAGLGNPGPEYAMNRHNVGFMVADLLAERMGGRFKRHGKAQAQVVEGRIGPPGPASRRVVLAKPMSYMNLSGGPVNALRDFYKVPVAHVVAVHDELDIDYGVLRLKLGGGDNGHNGLKSLTKAMGAEYHRVRCGIGRPPGRMPVADFVLKDFSSVERKELDWFVDRAADAVECLVTEGLERAQSAYNS
>NZ_CP010849.1|WP_044387923.1|3334659_3335151_+|hypothetical-protein
MPASAPRSRQAPAAVLRFGRVAAMGTVSVLILIAGVWASWGTAQHVMLTKGRERGTVEVARCGGGACSGPYRPVSAGSQARSRVVLADTVAVAEGRTYAVVVKPGGVEAVPSGVAGILYAWVPLGGALLLASVVVAGGLRRTGAAWVLAGSGVALLTAAFATV
>NZ_CP010849.1|WP_044382058.1|3335282_3336062_+|LPXTG-cell-wall-anchor-domain-containing-protein
MRTLTRAGVLACASSAALLLAPAAHATAPGDNGTVKIHDAATGEELRRNEPHVCTFYLDAFGFDGGQRVDWHIESWAPTAGVKGETVKSGSLTLDGEGHGRTNDLSLPDGHYKLFWNFAGEKGSAKHKVFWTDCAESEEPGTAPGGSAAPPSSPPATADAPPVSPAPSESVPSDSVPSDSASSGASAPSGSAAPSGSSTSSAAPVPSGAPSASAQGGVVEGDLAETGSGIPAGLLSAAAAVLVAAGGFLVFRRRRAARG
>NZ_CP010849.1|WP_044382059.1|3336146_3338888_-|phosphoenolpyruvate-carboxylase
MSSADDLTTRSTTTSSELRADIRRLGDLLGETLVRQEGPELLDLVEKVRRLTREDGEAAAELLRGTELETAAKLVRAFSTYFHLANITEQVHRGRELRARRAAEGGLIARTADRLKDADPEHLREAVANLNVRPVFTAHPTEAARRSVLNKLRRVAALLDTPVLESDRRRHDTRLAENIDLVWQTDELRVVRPEPADEARNAIYYLDELHAGAVGDVLEDLTAELERVGVKLPDGTRPLTFGTWIGGDRDGNPNVTPQVTWDVLILQHEHGINDALETIDELRGLLSNSIRYTGATRELLDSLQADLERLPEISPRYKRLNAEEPYRLKATCIRQKLENTKKRLADGTPHQPGRDYLGTSELLADLRIIQTSLREHRGGLFADGRLARTIRTLGAFGLQLATMDVREHADAHHHALGQLFDRLGEESWRYADMPREYRAKLLAKELRSRRPLAPSPAPVDAAGEKTLGVFQTVKRALEVFGPEVIESYIISMCQGADDVFAAAVLAREAGLIDLHAGWAKIGIVPLLETTDELKAADTILEDMLSDPSYRRLVALRGDVQEVMLGYSDSSKFGGITTSQWEIHRAQRRLRDVAHRYGVRLRLFHGRGGTVGRGGGPTHDAILAQPWGTLEGEIKVTEQGEVISDKYLIPSLARENLELTVAATLQASALHTAPRQSQEALARWDAAMDVVSDAAHAAYRRLVEDPDLPAYFFASTPVDQLADLHLGSRPSRRPDSGAGLDGLRAIPWVFGWTQSRQIVPGWFGVGSGLKALREAGLDTVLEEMYGQWHFFRNFISNVEMTLAKTDLRIAAHYVDTLVPDELRHVFDTIRAEHELTVREVLRVTGEEELLDAQPVLKQTFAIRDAYLDPISYLQVALLKRQRDAAAAGEQPDPLLSRALLLTVNGVAAGLRNTG
>NZ_CP010849.1|WP_044382060.1|3339179_3340190_+|acyl-CoA-desaturase
MTTSSDVIAQAPKAPDDTTTPSATLGGEQKRSIEQITLLLFITVPFLALLAAVPLAWGWGVSWLDLGLLVFFYFLGCHGITIGFHRHFTHGSFKAKRPLKIALAIMGSMAVEGPLVRWVADHRKHHKYSDHEGDPHSPWRYGETVPALMKGLWWAHIGWMFDEEQTPQDKYAPDLIKDRTLRAISRQFALWTAVSLLLPPLIGGLVTMSWWGAFTAFFWGSLVRVALLHHVTWSINSICHAVGKRPFKSRDRSGNVWWLAILSCGESWHNLHHADPTSARHGVERGQLDSSARLIRWFEQLGWAYDVRWPSRSRIDARRNDGEGGSRRGKESVKAA

Crispr_ID: NZ_CP010849_14

• CRISPR_ID: NZ_CP010849_14
• CRISPR_location: 3984695-3984897
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP010849_14

Consensus_repeat	Method
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAC	CRISPRCasFinder

spacers of NZ_CP010849_14

>14.1|3984738|37|NZ_CP010849|CRISPRCasFinder
GCGATCCTGCGCAAGAAGGCGGTGCAGGAGCAGCTCA
>14.2|3984818|37|NZ_CP010849|CRISPRCasFinder
GCTGGAGAGCACGATCTGCTTGTTGGCGTTGTGGAGG

CRISPR arrays and Neighbor proteins around NZ_CP010849_14

CRISPR arrays

The CRISPR arrays of NZ_CP010849_14

>merge|NZ_CP010849|14|3984695-3984897|CRISPRCasFinder
TCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGCGCGATCCTGCGCAAGAAGGCGGTGCAGGAGCAGCTCACGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGACGCTGGAGAGCACGATCTGCTTGTTGGCGTTGTGGAGGCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAC

>NZ_CP010849|14|13|3984695-3984897|CRISPRCasFinder
TCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGC	GCGATCCTGCGCAAGAAGGCGGTGCAGGAGCAGCTCA
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAC	GCTGGAGAGCACGATCTGCTTGTTGGCGTTGTGGAGG
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_003956500.1|3986332_3986470_+|50S-ribosomal-protein-L34	unknown	unknown	gnl|CDD|366117
NZ_CP010849.1|WP_078969220.1|3986491_3986863_+|ribonuclease-P-protein-component	unknown	unknown	gnl|CDD|376392
NZ_CP010849.1|WP_078969221.1|3986859_3987243_+|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl|CDD|184650
NZ_CP010849.1|WP_044382716.1|3978597_3979134_-|DUF721-domain-containing-protein	unknown	unknown	gnl|CDD|179552
NZ_CP010849.1|WP_044382706.1|3970924_3971326_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378956
NZ_CP010849.1|WP_029383828.1|3989178_3989898_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl|CDD|234637
NZ_CP010849.1|WP_044382726.1|3991373_3992471_+|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl|CDD|275105
NZ_CP010849.1|WP_044382720.1|3980309_3981185_-|decarboxylating-6-phosphogluconate-dehydrogenase	unknown	unknown	gnl|CDD|236582
NZ_CP010849.1|WP_029383832.1|3993510_3993843_-|thioredoxin	unknown	unknown	gnl|CDD|200072
NZ_CP010849.1|WP_044382724.1|3988539_3989052_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|224760
NZ_CP010849.1|WP_044382727.1|3992799_3993417_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP010849.1|WP_159392897.1|3970421_3970712_-|anti-sigma-factor-antagonist	unknown	unknown	gnl|CDD|132914
NZ_CP010849.1|WP_044382718.1|3979130_3980273_-|DNA-replication/repair-protein-RecF	unknown	unknown	gnl|CDD|234608
NZ_CP010849.1|WP_044382723.1|3987246_3988524_+|membrane-protein-insertase-YidC	unknown	unknown	gnl|CDD|234941
NZ_CP010849.1|WP_078648219.1|3990303_3991377_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NZ_CP010849.1|WP_029383015.1|3981404_3982535_-|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl|CDD|236089
NZ_CP010849.1|WP_044382715.1|3976033_3978127_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl|CDD|235542
NZ_CP010849.1|WP_078969219.1|3972638_3973379_-|DUF3566-domain-containing-protein	unknown	unknown	gnl|CDD|378809
NZ_CP010849.1|WP_044382709.1|3971588_3972173_-|hypothetical-protein	unknown	unknown	gnl|CDD|367636
NZ_CP010849.1|WP_044382713.1|3973396_3975991_-|DNA-gyrase-subunit-A	unknown	unknown	gnl|CDD|235502

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_003956500.1|3986332_3986470_+|50S-ribosomal-protein-L34	gnl|CDD|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	1.05121e-08
NZ_CP010849.1|WP_078969220.1|3986491_3986863_+|ribonuclease-P-protein-component	gnl|CDD|376392	pfam00825, Ribonuclease_P, Ribonuclease P.	5.1834e-28
NZ_CP010849.1|WP_078969221.1|3986859_3987243_+|membrane-protein-insertion-efficiency-factor-YidD	gnl|CDD|184650	PRK14369, PRK14369, membrane protein insertion efficiency factor YidD.	1.08323e-68
NZ_CP010849.1|WP_044382716.1|3978597_3979134_-|DUF721-domain-containing-protein	gnl|CDD|179552	PRK03195, PRK03195, DUF721 family protein.	1.95518e-35
NZ_CP010849.1|WP_044382706.1|3970924_3971326_+|MarR-family-transcriptional-regulator	gnl|CDD|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	0.000114737
NZ_CP010849.1|WP_029383828.1|3989178_3989898_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl|CDD|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	7.55455e-71
NZ_CP010849.1|WP_044382726.1|3991373_3992471_+|ParB/RepB/Spo0J-family-partition-protein	gnl|CDD|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	4.00156e-70
NZ_CP010849.1|WP_044382720.1|3980309_3981185_-|decarboxylating-6-phosphogluconate-dehydrogenase	gnl|CDD|236582	PRK09599, PRK09599, NADP-dependent phosphogluconate dehydrogenase.	0
NZ_CP010849.1|WP_029383832.1|3993510_3993843_-|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	7.94481e-47
NZ_CP010849.1|WP_044382724.1|3988539_3989052_+|single-stranded-DNA-binding-protein	gnl|CDD|224760	COG1847, Jag, Predicted RNA-binding protein [General function prediction only].	2.82642e-43
NZ_CP010849.1|WP_044382727.1|3992799_3993417_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.21583e-05
NZ_CP010849.1|WP_159392897.1|3970421_3970712_-|anti-sigma-factor-antagonist	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.69142e-25
NZ_CP010849.1|WP_044382718.1|3979130_3980273_-|DNA-replication/repair-protein-RecF	gnl|CDD|234608	PRK00064, recF, recombination protein F; Reviewed.	7.75069e-157
NZ_CP010849.1|WP_044382723.1|3987246_3988524_+|membrane-protein-insertase-YidC	gnl|CDD|234941	PRK01315, PRK01315, putative inner membrane protein translocase component YidC; Provisional.	0
NZ_CP010849.1|WP_078648219.1|3990303_3991377_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	1.43703e-89
NZ_CP010849.1|WP_029383015.1|3981404_3982535_-|DNA-polymerase-III-subunit-beta	gnl|CDD|236089	PRK07761, PRK07761, DNA polymerase III subunit beta; Validated.	0
NZ_CP010849.1|WP_044382715.1|3976033_3978127_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl|CDD|235542	PRK05644, gyrB, DNA gyrase subunit B; Validated.	0
NZ_CP010849.1|WP_078969219.1|3972638_3973379_-|DUF3566-domain-containing-protein	gnl|CDD|378809	pfam12089, DUF3566, Transmembrane domain of unknown function (DUF3566). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 136 to 304 amino acids in length. This region represents a transmembrane region found at the C-terminus of the proteins.	5.88026e-54
NZ_CP010849.1|WP_044382709.1|3971588_3972173_-|hypothetical-protein	gnl|CDD|367636	pfam03752, ALF, Short repeats of unknown function. This set of repeats is found in a small family of secreted proteins of no known function, though they are possibly involved in signal transduction. ALF stands for Alanine-rich (AL) - conserved Phenylalanine (F).	1.34931e-06
NZ_CP010849.1|WP_044382713.1|3973396_3975991_-|DNA-gyrase-subunit-A	gnl|CDD|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0

Protein sequences

>NZ_CP010849.1|WP_029383015.1|3981404_3982535_-|DNA-polymerase-III-subunit-beta
MKIRVERDVLAEAVAWAARSLPARPPAPVLAGLLLKAEDGQLSLSSFDYEVSARVSVEAEVEEEGTVLVSGRLLADISRALPNRPVEISTDGVRATVVCGTSRFTLHTLPVEEYPALPQMPNATGTVPGEVFSSAVQQVAIAAGRDDTLPVLTGVRIEIEGDTVTLASTDRYRFAVREFLWKPENPDASAVALVPAKTLLDTAKSLTSGDNVILALSGSGAGEGLIGFEGAGRRTTTRLLEGDLPKYRTLFPTEFNSVAVIETAPFVEAVKRVALVAERNTPVRLSFEQGVLILEAGSSDDAQAVERVDAQLEGDDISIAFNPTFLLDGLSAIDSPVAQLSFTTSTKPALLSGKPAVDAEADEAYKYLIMPVRLSG
>NZ_CP010849.1|WP_044382720.1|3980309_3981185_-|decarboxylating-6-phosphogluconate-dehydrogenase
MELGLVGLGKMGGNMRERIRRAGHTVIGYDRNPDVADVHSLEELVGKLKGPRVVWVMVPAGEPTQSTIDQLAELLEPGDVVVDGGNSRWTDDEKHAEELAAKGIGFVDCGVSGGVWGLENGYALMYGGDAENVAKVQPVFDALKPEGDFGSVHAGKVGAGHFAKMVHNGIEYAMMQAYAEGWELLEKVDSVENVREVFRSWQEGTVIRSWLLDLAVNALDDDEHLEGLRGYAQDSGEGRWTVEAAIDNAVPLPAITASLFARFASRQEDSPQMKMIAALRNQFGGHAVEKK
>NZ_CP010849.1|WP_044382718.1|3979130_3980273_-|DNA-replication/repair-protein-RecF
MHVTHLSLADFRSYARVEVPLDPGVTAFVGPNGQGKTNLVEAVGYLATLGSHRVSSDAPLVRMGADRAVIRAQVRQGERQQLIELELNPGRANRARINRSSQVRPRDVLGIVRTVLFAPEDLALVKGDPGERRRFLDELITARSPRMAGVRSDYDRVLKQRNTLLKSAALARRHGGRTLDLSTLDVWDQHLARAGAELLAQRLDLIAAIGPLADKAYEQLAPGGGPVVLEYKPSAPGEAHTREDLYEQLMAALADTRKQEIERGVTLVGPHRDDLLLKLGELPAKGYASHGESWSCALALRLASYDLLRAEGNEPVLVLDDVFAELDARRRERLAELVAPGEQVLVTAAVEDDVPHVLSGTRFAVSGGTVEPVRKEGERG
>NZ_CP010849.1|WP_044382716.1|3978597_3979134_-|DUF721-domain-containing-protein
MTTDGPPPGKAAPQPSGVDLARVALRAAREAARARGDAAQQKKQARRGGLRSGARADGRDPMRLGSAINRLITERGWETPAAVGGVMGRWPQIVGDDVAKHCVPEKYDEDERVLVVRCDSTAWATNLRLLAPTLVARLNEDLGHGSVRMLRVQGPGGPARRYGPLRAPGSTGPGDTYG
>NZ_CP010849.1|WP_044382715.1|3976033_3978127_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MLCQKGRFVADSGNPNENIPSTDAGADDAASTSSGEVTASYDASAITVLEGLDAVRKRPGMYIGSTGERGLHHLVYEVVDNSVDEALAGHADTIDVTILADGGVRVVDNGRGIPVGIVPSEGKPAVEVVLTVLHAGGKFGGGGYAVSGGLHGVGVSVVNALSSKVSVEVRTDGHRWTQDYKLGVPTAPLAKHEATEETGTSVTFWADPDIFETTEYSFETLSRRFQEMAFLNKGLTIKLTDERESAKATAGADEAGADELAEEQKVKSVTYHYEGGIVDFVKYLNSRKGDVVHPTVIDLEAEDKDKSLSLEVAMQWNSGYSEGVYSFANIIHTHEGGTHEEGFRAALTSLINKYARDKKLLREKDDNLTGDDIREGLTAIISVKLSEPQFEGQTKTKLGNTEAKTFVQKAVYEHLNDWLDRNPNEAADIIRKGIQAATARVAARKARDLTRRKGLLETASLPGKLSDCQSNDPTKCEIFIVEGDSAGGSAKSGRNPEYQAILPIRGKILNVEKARIDKILQNQEIQALISAFGTGVHEDFDIEKLRYHKIILMADADVDGQHINTLLLTFLFRFMRPLVEAGHVFLSRPPLYKIKWGKDDIEYAYSDRERDALLELGRQRGKRIREDSIQRFKGLGEMNAEELRVTTMDQEHRVLGQVTLDDAAQADDLFSVLMGEDVEARRAFIQRNAKDVRFLDI
>NZ_CP010849.1|WP_044382713.1|3973396_3975991_-|DNA-gyrase-subunit-A
MTDENTPVTTSEGDALAMRVEPVGLETEMQRSYLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMYDGGYRPERGFYKCARVVGDVMGNYHPHGDSSIYDALVRLAQPWAMRMPLVDSNGNFGSPGNDPAAAMRYTECKMAPLSMEMVRDIDEETVDFTDNYDGRSQEPTVLPARFPNLLINGSAGIAVGMATNIPPHNLREVAAGAQWYLENPEASHEELLDALIERIKGPDFPTGALVVGRKGIEEAYRTGRGSITMRAVVEVEEIQNRQCLVVTELPYQVNPDNLAQKIADLVKDGRIGGIADVRDETSSRTGQRLVIVLKRDAVAKVVLNNLYKHTDLQTNFGANMLALVDGVPRTLSLDAFIRHWVTHQIEVIVRRTRFRLRKAEERAHILRGLLKALDAIDEVIALIRRSDTVEIARGGLMGLLDIDEIQANAILEMQLRRLAALERQKIVQEHDELQAKINEYNEILASPVRQRGIVSEELAAIVEKYGDDRKTKLIPYEGDMSIEDLIAEEDIVVTVTRGGYIKRTKTDDYRAQKRGGKGVRGTKLKEDDIVDHFFVSTTHHWLLFFTNKGRVYRAKAYELPEAGRDARGQHVANLLAFQPDEAIAEILAIRDYEAAPYLVLATKSGLVKKTPLKDYDSPRSGGVIAINLRAREDGTDDELIGAELVSADDDLLLISKKAQSIRFTASDDTLRPMGRATSGVKGMSFREGDELLSMNVVRPGTFVFTATDGGYAKRTPVDEYRVQGRGGLGIKAAKIVEDRGSLVGALVVEETDEILAITLSGGVIRTRVNEVRETGRDTMGVQLINLGKRDAVVGIARNAEAGREAEEVDGDIAVDETAEGTVDTGTDEGEAPSAE
>NZ_CP010849.1|WP_078969219.1|3972638_3973379_-|DUF3566-domain-containing-protein
MSGATGAGSAGTSPGTQTDGGRGSAAHAPETSSSSSSSSSSYDTHGSQGGTVTDTRGPHTQQYAAGAGPAAPGAGAAQQPASPLPGERQPQQPAGPYHPPQAYQTPTAAAGVRRPRTGAGTTPRVRKARLRVAKADPWSVMKVSFLLSIALGICTIVAAAVLWMVMDAMGVFSTVGGTISEATGSNESNGFDLQSFLSLPNVLLFTSIIAVIDVVLATALATLGAFIYNLSAGFVGGVELTLAEDE
>NZ_CP010849.1|WP_044382709.1|3971588_3972173_-|hypothetical-protein
MRSTRVILAVAAGALAPALLLATPSMAASLAPAATVATAGSPYDEMSADDLRVAISRILADPDSGKRVIREANALLDSGTVEEMRAWLETGYALAQAEDDRVALVRILADPDSGKRVIAEVNQLLDDDDPQQTRAWLETGYRLAQAEDDRVAIARLLADPDISDALRAAAGAALDDNTPEALRHFLEVGQYEVG
>NZ_CP010849.1|WP_044382706.1|3970924_3971326_+|MarR-family-transcriptional-regulator
MRGAVPEPHTGWTFLTNHARVLAAIADDPDSRIRDIAAYCRLTERAVQKIISDLEREGYLSHTRRGRSNTYRIEPGVPLRHPAEVEAGVTVANLLSALARHDAQRSQNTTDETPQPQPQPQQPQQRPEPSLTT
>NZ_CP010849.1|WP_159392897.1|3970421_3970712_-|anti-sigma-factor-antagonist
MSLRGDIDMTAEAEVRQALLAPPDADAPRTVVDLSQVSFMDSTGFNALISAHAHATAHSGWVRVATPPPMVKRMFQMLGIDEVISSYPTVKDALTG
>NZ_CP010849.1|WP_003956500.1|3986332_3986470_+|50S-ribosomal-protein-L34
MSKRTFQPNNRRRAKTHGFRLRMRTRAGRAILASRRSKGRARLSA
>NZ_CP010849.1|WP_078969220.1|3986491_3986863_+|ribonuclease-P-protein-component
MLPTENRLRRREDFATAVRRGRRAGRPNLVVHLRSGATDPHAPGESAPPTRAGFVVSKAVGGAVVRNKVKRRLRHLMRERIALFPPGSLVVVRALPGAGDADHAQLARDLDAALQRLLGGGAR
>NZ_CP010849.1|WP_078969221.1|3986859_3987243_+|membrane-protein-insertion-efficiency-factor-YidD
MKYPLLALIKLYQWTISPLLGPVCKYYPSCSHYGYTAIDRHGALKGTALTAWRILRCNPWSLGGVDHVPPRKRPRWHEMLRDAWRARRGGPSAAAPATEGQTSQASSSSPSSPSGPAAETSSHAQGA
>NZ_CP010849.1|WP_044382723.1|3987246_3988524_+|membrane-protein-insertase-YidC
MDTIASLFSFITTPVSWVIVQFHKVYGELFGPDTGWAWGLSIVSLVILIRICLIPLFVKQIKATRAMQTLQPEMKKIQERYKNDRQRQSEEMMKLYKETGTNPLSSCLPILAQSPFFFALYHVLNSIASNDTIGVINTRLLDSAQKAHIFGAPLAAKFTDSASKVEALGATLTDVRVITAIMIVLMSASQFFTQRQLMTKNVDTTVKTPFMQQQKMLMYIFPIMFAVFGINFPVGVLVYWLTTNVWTMGQQMYVIHNNPTPGSKAQAAYLERLYKRVTHHGKTRGRGERAIVKAIVAKGRDRNEFERKFINGLNKAGLAAQADGTVVKSEPTATAQAADGEATATAAAAGKRQQPKRQTKAQRQGGAKAAGEPETKTSLIKSDQPQDSQSAGGKKGGQKPAAGTRSKAQSGQRKGPQRPKSPSKK
>NZ_CP010849.1|WP_044382724.1|3988539_3989052_+|single-stranded-DNA-binding-protein
MTEGTTSAAAEGADTLTRLEQEGEIAADYLEGLLDIADLDGDIDMDVEADRASVSIISDTGSRDLQKLVGRDGEVLEALQELTRLAVHRETGDRSRLMLDIAGYRARKRSELSELGAKAAAEVKSSGEPVRLDPMTPFERKVVHDAIKAAGLRSESEGEEPQRFVVVLPA
>NZ_CP010849.1|WP_029383828.1|3989178_3989898_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MTEAAELPPAPEQAREVFGDRFADAVRYAELLAEAGVQRGLIGPREVPRLWERHLLNCAVLAEAVPEGVTVCDVGSGAGLPGIPLALVREDLKITLLEPLLRRTNFLTEVVELLGLDHVTVVRGRAEEVMGKLPPVHVVTARAVAPLDRLATWGIPLLRPYGEMLALKGDTAEEELKSAATALSKLGAVETSILHVGEGVVDPMSTVVRVEVGESPGGVRFAAKRAKAARTGRTRRRRG
>NZ_CP010849.1|WP_078648219.1|3990303_3991377_+|ParA-family-protein
MGGSVHCEPEVEESESLRSDANIAGPMTDPVPGPRTESMGADVSRETPPPMDDTPIGRSAQLAVEALGRAGEGMPRPEQTRIIVVANQKGGVGKTTTTVNLAASLALHGGRVLVIDLDPQGNASTALGIDHHAEVPSIYDVLVESKPLSEVVQPVPDVEGLFCAPATIDLAGAEIELVSLVARESRLQRAIQAYEQPLDYILIDCPPSLGLLTVNALVAGQEVLIPIQCEYYALEGLGQLLRNVDLVRGHLNPTLHVSTILLTMYDGRTRLASQVADEVRNHFGDEVLRTSIPRSVRISEAPSYGQTVLTYDPGSSGALSYLEAAREIALRGVGVSYDPTHAHIGAQNNPNMVEGMQ
>NZ_CP010849.1|WP_044382726.1|3991373_3992471_+|ParB/RepB/Spo0J-family-partition-protein
MSERRRGLGRGLGALIPPAPTEKTVASAALGGTASTSPAVVPGLTTDRGVAAAKVATLPRVSRETEESAGASAEMPATPIGAHFAEIPLDAITPNPRQPRVVFDEDALAELVTSIKEVGLLQPVVVRQVGPASYELIMGERRWRACREAGLKAIPAIVRATEDEKLLLDALLENLHRAQLNPLEEAAAYDQLLNEFNCTHDQLADRIGRSRPQVSNTLRLLKLSSAVQRRVAAGVLSAGHARALLSVEDPEEQDRLAYRIVAEGLSVRAVEEIVTLMGSRPQKPQRAKGPRAGSRVSPALTDLATRLSDRFETRVKVDLGQKKGKITVEFASLEDLERILGTLAPGEGPVLQQKLEKGDSEESDS
>NZ_CP010849.1|WP_044382727.1|3992799_3993417_+|GNAT-family-N-acetyltransferase
MGRRLVPLTLDNLQDLPKRCRSCVFWELDPVSGEAAVKAGTPALEKEAWISAVLLDWGSCGRVVYVDDVPVGFVLYAPPAYVPRSTAFPTSPVSPDAVQLMTAFIMPGYQGQGLGRVMVQTVAKDLLRRGFKAIEAFGDARWKEPACLLPADHLLAVGFKTVRPHPVHPRLRLELRSTLSWKEDVEMALDRLLGAVQKEPALRPL
>NZ_CP010849.1|WP_029383832.1|3993510_3993843_-|thioredoxin
MAGTLKNVTDASFEQDVLKSDKPVLVDFWAAWCGPCRQIAPSLEAIAAEYGDKIEVVKLNIDENPGTAAKYGVMSIPTLNVYQSGDVVKTIVGAKPKAAIVRDLEEFIAD

Crispr_ID: NZ_CP010849_15

• CRISPR_ID: NZ_CP010849_15
• CRISPR_location: 4829330-4829446
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_15

Consensus_repeat	Method
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA	CRISPRCasFinder

spacers of NZ_CP010849_15

>15.1|4829372|33|NZ_CP010849|CRISPRCasFinder
CTGCTGCAGAGCGCGCTGTTCTCGACGTACAAG

CRISPR arrays and Neighbor proteins around NZ_CP010849_15

CRISPR arrays

The CRISPR arrays of NZ_CP010849_15

>merge|NZ_CP010849|15|4829330-4829446|CRISPRCasFinder
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGACTGCTGCAGAGCGCGCTGTTCTCGACGTACAAGCGTAATAACTTCGTATAGTATACATTATACGAAGTTATACGA

>NZ_CP010849|15|14|4829330-4829446|CRISPRCasFinder
CGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA	CTGCTGCAGAGCGCGCTGTTCTCGACGTACAAG
CGTAATAACTTCGTATAGTATACATTATACGAAGTTATACGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_052808648.1|4835542_4836760_-|hypothetical-protein	unknown	unknown	gnl|CDD|227829
NZ_CP010849.1|WP_044383385.1|4822015_4823134_+|adenosine-deaminase	unknown	unknown	gnl|CDD|236480
NZ_CP010849.1|WP_044383394.1|4828350_4829172_+|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NZ_CP010849.1|WP_044383387.1|4823725_4823929_-|PspC-domain-containing-protein	unknown	unknown	gnl|CDD|377200
NZ_CP010849.1|WP_044383397.1|4831112_4832003_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|365919
NZ_CP010849.1|WP_044383391.1|4825647_4827384_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP010849.1|WP_078969268.1|4829848_4830553_-|uridine-kinase	unknown	unknown	gnl|CDD|223645
NZ_CP010849.1|WP_029383417.1|4839044_4839869_-|purine-nucleoside-phosphorylase	unknown	unknown	gnl|CDD|236183
NZ_CP010849.1|WP_044383396.1|4830634_4831039_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044388248.1|4834707_4835397_+|PH-domain-containing-protein	unknown	unknown	gnl|CDD|371225
NZ_CP010849.1|WP_044383399.1|4836925_4838572_-|phospho-sugar-mutase	unknown	unknown	gnl|CDD|100092
NZ_CP010849.1|WP_044383383.1|4821094_4821856_-|dienelactone-hydrolase	unknown	unknown	gnl|CDD|223477
NZ_CP010849.1|WP_044383390.1|4825051_4825648_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044383393.1|4827380_4828067_-|two-component-system-response-regulator-AfsQ1	unknown	unknown	gnl|CDD|223816
NZ_CP010849.1|WP_044383388.1|4824083_4824635_-|VanZ-family-protein	unknown	unknown	gnl|CDD|377417
NZ_CP010849.1|WP_044383398.1|4833453_4834416_-|deoxyribose-phosphate-aldolase	unknown	unknown	gnl|CDD|188646
NZ_CP010849.1|WP_044388246.1|4831995_4833441_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143429
NZ_CP010849.1|WP_029383416.1|4839961_4840399_-|gamma-glutamylcyclotransferase	unknown	unknown	gnl|CDD|372719
NZ_CP010849.1|WP_044383386.1|4823310_4823643_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044383381.1|4820069_4821023_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176125

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_052808648.1|4835542_4836760_-|hypothetical-protein	gnl|CDD|227829	COG5542, COG5542, Predicted integral membrane protein [Function unknown].	1.15332e-07
NZ_CP010849.1|WP_044383394.1|4828350_4829172_+|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	1.24384e-61
NZ_CP010849.1|WP_044383387.1|4823725_4823929_-|PspC-domain-containing-protein	gnl|CDD|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	3.87365e-20
NZ_CP010849.1|WP_044383397.1|4831112_4832003_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|365919	pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3. Succinate-semialdehyde dehydrogenase EC:1.2.1.16. Lactaldehyde dehydrogenase EC:1.2.1.22. Benzaldehyde dehydrogenase EC:1.2.1.28. Methylmalonate-semialdehyde dehydrogenase EC:1.2.1.27. Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.9. Delta-1-pyrroline-5-carboxylate dehydrogenase EC: 1.5.1.12. Acetaldehyde dehydrogenase EC:1.2.1.10. Glutamate-5-semialdehyde dehydrogenase EC:1.2.1.41. This family also includes omega crystallin, an eye lens protein from squid and octopus that has little aldehyde dehydrogenase activity.	3.49589e-41
NZ_CP010849.1|WP_044383391.1|4825647_4827384_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.30645e-46
NZ_CP010849.1|WP_044388246.1|4831995_4833441_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143429	cd07111, ALDH_F16, Aldehyde dehydrogenase family 16A1-like. Uncharacterized aldehyde dehydrogenase family 16 member A1 (ALDH16A1) and other related sequences are present in this CD. The active site cysteine and glutamate residues are not conserved in the human ALDH16A1 protein sequence.	0
NZ_CP010849.1|WP_029383417.1|4839044_4839869_-|purine-nucleoside-phosphorylase	gnl|CDD|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	3.53054e-134
NZ_CP010849.1|WP_044388248.1|4834707_4835397_+|PH-domain-containing-protein	gnl|CDD|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	4.06808e-05
NZ_CP010849.1|WP_044383399.1|4836925_4838572_-|phospho-sugar-mutase	gnl|CDD|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NZ_CP010849.1|WP_044383383.1|4821094_4821856_-|dienelactone-hydrolase	gnl|CDD|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	0.00115705
NZ_CP010849.1|WP_078969268.1|4829848_4830553_-|uridine-kinase	gnl|CDD|223645	COG0572, Udk, Uridine kinase [Nucleotide transport and metabolism].	5.7483e-15
NZ_CP010849.1|WP_044383393.1|4827380_4828067_-|two-component-system-response-regulator-AfsQ1	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.95889e-81
NZ_CP010849.1|WP_044383388.1|4824083_4824635_-|VanZ-family-protein	gnl|CDD|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	2.8874e-22
NZ_CP010849.1|WP_044383398.1|4833453_4834416_-|deoxyribose-phosphate-aldolase	gnl|CDD|188646	cd00959, DeoC, 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family. 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family. DERA belongs to the class I aldolases and catalyzes a reversible aldol reaction between acetaldehyde and glyceraldehyde 3-phosphate to generate 2-deoxyribose 5-phosphate. DERA is unique in catalyzing the aldol reaction between two aldehydes, and its broad substrate specificity confers considerable utility as a biocatalyst, offering an environmentally benign alternative to chiral transition metal catalysis of the asymmetric aldol reaction.	1.23043e-78
NZ_CP010849.1|WP_029383416.1|4839961_4840399_-|gamma-glutamylcyclotransferase	gnl|CDD|372719	pfam13772, AIG2_2, AIG2-like family. This family is found in bacteria and metazoa.	8.17053e-22
NZ_CP010849.1|WP_044383385.1|4822015_4823134_+|adenosine-deaminase	gnl|CDD|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	5.55237e-157
NZ_CP010849.1|WP_044383381.1|4820069_4821023_+|LysR-family-transcriptional-regulator	gnl|CDD|176125	cd08434, PBP2_GltC_like, The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold. GltC, a member of the LysR family of bacterial transcriptional factors, activates the expression of gltA gene of glutamate synthase operon and is essential for cell growth in the absence of glutamate. Glutamate synthase is a heterodimeric protein that encoded by gltA and gltB, whose expression is subject to nutritional regulation. GltC also negatively auto-regulates its own expression. This substrate-binding domain has strong homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.08715e-85

Protein sequences

>NZ_CP010849.1|WP_044383394.1|4828350_4829172_+|SigE-family-RNA-polymerase-sigma-factor
MNTLHGTITSGAVVTRLHDMHAHRGSEKPGGGAGTALLERGREPGAGRGCVRGAGRQHTAYGPQGLQPRAVADAHTGETQGGAAYGEAPGERRSPARAVDAEAAFTAYVRERRASLYATAYHLTGDRFEAEDLLQSALFSTYKAWDRISDKAAVGGYLRRTMTNLHISAWRRRKLNEYPTEELPETPGDTDAMRGTELRAVLWQALARLPETQRTMLVLRYYEGRTDPEIADILGISVGTVKSSIWRSLRRLRDDEALSFGRDQEDAFGELVA
>NZ_CP010849.1|WP_044383393.1|4827380_4828067_-|two-component-system-response-regulator-AfsQ1
MRPVPSLLLIEDDDAIRTALELSLTRQGHRVATAASGEDGLKLLREQRPDLIVLDVMLPGIDGFEVCRRIRRTDQLPIILLTARSDDIDVVVGLESGADDYVVKPVQGRVLDARIRAVLRRGERESSDSATFGSLVIDRAAMTVTKNGEDLQLTPTELRLLLELSRRPGQALSRQQLLRLVWEHDYLGDSRLVDACVQRLRAKVEDVPSSPTLIRTVRGVGYRLDPPQ
>NZ_CP010849.1|WP_044383391.1|4825647_4827384_-|HAMP-domain-containing-histidine-kinase
MTREHQGGSRGWAAARKGVWSRLRLTSLRLRLVVVFGLVALTAAVSASGIAYWLNREAVLTRAQDAVLRDFEREMQNRAGALPEHPTQEELQRTAGQMADSERQFSVLLVAEGREGGTVYGTSGDLGGFTPADVPASLREAVDKRQKITAANKHAYHLYWQRIVHGDTPYLVAGTKVIGGGPTGYMLQSLEPEAKDLGSLAWSLGIATGLALIGSALLAQAAASTVLKPVQRLGVAARRLGEGKLDTRLRVSGTDELADLSRTFNSAAEALEKRVADMAAREAASRRFVADMSHELRTPLTAITAVTEVLEEELEFEGGGIDPMIEPAVRLVVSETRRLNDLVENLMEVTRFDAGTARLVLDDVDVADQITACIDARAWLDAVELDAERGIHARLDPRRLDVILANLIGNALKHGGSPVRVSVTESDGPATAGPAGTAGAEDPVNAEHAETSAGTEGTEGAQYAEGAEVVIRVRDHGPGIPEDVLPHVFDRFYKASASRPRSEGSGLGLSIALENAHIHGGRITAGNHPEGGAVFTLRLPRDASNLTVDGADGAGVAGGAGDGGAEGKGMGKDAKGRG
>NZ_CP010849.1|WP_044383390.1|4825051_4825648_-|hypothetical-protein
MTVRRLLGLPVLAVLLAGCGIRPTEVPTDFGPAPSRVRCSPPDTAAPAAPGTPVQVFLVCGASLVAVDRTVRVPDGATGPQRRLLVAQGLLDQLAEPPSDTEKAAGYGTDVRGGTTVTGPRPGDPEDTLRLDDSPADLSAYALSQIVCTFSDSAAAEGDGSVVLGGPGDRPPRRYTCTDEVRVRPGGSGPPSSALTGG
>NZ_CP010849.1|WP_044383388.1|4824083_4824635_-|VanZ-family-protein
MQRQGSIGGSAAIRIRVTGGALLVAHLALVAWCTLRPLDVPWVMPANVHPLDGIRADLALGWPEAARRIGEGLALLAPLGVLLPMAGGRLSVSPLASLFRTVAAGALLSLGIELLQTGVPGRVVDIDSLLLNTAGVALVHLLVVPAGRAWIRRRSARRSGADLLREERSQGRTPTIPRVGIAP
>NZ_CP010849.1|WP_044383387.1|4823725_4823929_-|PspC-domain-containing-protein
MSRLARPTDGRMIAGVCAALARRFGTSVTTMRAIFLLSCLLPGPQFLLYIALWVLLPSEEKTARTAW
>NZ_CP010849.1|WP_044383386.1|4823310_4823643_+|hypothetical-protein
MKQSAAKTLGVAALGVAFAAAGAGTAGAVNGVPDPGQALDPITRTLPAESLTRSLPGAGEALSQGETAAEGGLRAVQPTAQQLPQSPTDPLAGLLGGLPVDRLPVTLPLL
>NZ_CP010849.1|WP_044383385.1|4822015_4823134_+|adenosine-deaminase
MTSQSTAKSPTPDQIRRAPKVLLHDHLDGGLRPATIVELARATGYSKLPHTDPGKLGLWFREAADSGSLERYLETFSHTVAVMQTREALVRVAAECAEDLARDGVVYAEVRYAPEQHLEGGLTLEEVVEAVDEGFREGERRAREAGHRIRVGALLTAMRHAARSLEIAELANRYRDAGVVGFDIAGAEAGHPPTRHLDAFEFLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDIEVREDGSVALGRLASYVRDKRIPLELCPSSNLQTGAASSYAEHPIGLLRRLHFRATVNTDNRLMSHTSMSREFEHLVEAFGYTLDDMQWFSVNAMKSAFIPFDERLAMINDVIKPGYAELKSEWLFR
>NZ_CP010849.1|WP_044383383.1|4821094_4821856_-|dienelactone-hydrolase
MAQQATPARTARLGRALGPEPTPVSGVVLLLPGGDEVSGRRPAPLLATASMRALGRRLSRAGRPEGLVAHVVHYRYRGWNGGEAHLARDASWAADEVVRRYGDVPVCLAGVGMGGRAALRAGGHDAVEAVVALAPWLPEEDVAASPEPVKQLAGRHVLIVHGTNDTRTDPELSFRLAARAKKANRDVCRFEVHSDGHGLHHYRDEVLALVEDFVMGVLFGRAFSRPVADALAAPPPLGLRMPLAAGFGTSLRR
>NZ_CP010849.1|WP_044383381.1|4820069_4821023_+|LysR-family-transcriptional-regulator
MVHQQRSQGRLSPSGDTEDIVALLAPRLAHFAGVARTEHVTRAAQEMNVPQSTLSRALVRLEQDLGVDLFARHGRTVSLTPAGRTFLASVERALAEIERAAEEVRADADPATGKVAFGFLHTMGAETVPGLLHAFRADHPRIRFSLVQNYGEAMLERLRAGELDLCLTSPVPDAPDLVARRLDEQKLRLVVPADHRLAARRRVRLAEAADEMFVTLEPGYGLRRITDALCQEAGFRPRVAFEGEEAETLRGLVAAGLGVALLPPPAVPRPGVVELTVTAPRAAREIGVAWLAGRPDTPPVAAFKRFLLSRRGHLLPD
>NZ_CP010849.1|WP_078969268.1|4829848_4830553_-|uridine-kinase
MTRAAKPFRRVVRWPPDTAHWCPVSSQPPIPTRVVLLCGPSGSGKSLLAARSGLPVLRLDDFYKEGTDPSLPLVAGSSDIDWDHPGSWDADAAVAAITELCRTGRTRIPVYDIALSARTGEEAVDIGRTPLFIAEGIFAAEIVTRCRDLGVLADALCLSRGPVTTFRRRFLRDLKEGRKSVPFLVRRGWRLMRQERTIIARQTALGAHACDRDEALGRLAAAAAGRCPAARTPA
>NZ_CP010849.1|WP_044383396.1|4830634_4831039_+|hypothetical-protein
MTRHASPRTHFARRALVALATAGAALGAGPATAAAGPAAPAGAAPPPPAAADDRGARTALSATTGTVRHAAGPVAALRPNPLAGTGVDPLANGVGTQVADFKPLSTRAVTDPVTQAPSVGGVPVAGRAAGLLGG
>NZ_CP010849.1|WP_044383397.1|4831112_4832003_-|aldehyde-dehydrogenase-family-protein
MSDARLSVFKTYKLYVGGKFPRSESGRVYEVTDTKGTWLANAPLSSRKDARDAVVAARKAFGGWSGATAYNRGQVLYRVAEMLEGRRDQFVREVAAAEGLSKSKAAEQVDATIDRWVWYAGWTDKIAQVTGGGNPVAGPFFNLSSPEPTGVVAVLAPQESSFLGLVSVVAPVIATGNTAVVVASERSPLPALSLAEVLATSDVPGGVVNILSGRTAEIAAPLAAHQDVNAIDLAGADAELAKELEIAAADNLKRVLRPQPVDDWTATPGIERMTAFLETKTVWHPTGSLGASGSSY
>NZ_CP010849.1|WP_044388246.1|4831995_4833441_-|aldehyde-dehydrogenase-family-protein
MEKQTPVFEYAPAPESRAVVDIAPSYGLFIDGEFAEAADGKVFKTVSPSTEEVLSEVAEAGEADVDRAVRAARKAFETWSALPGSERAKYLFRIARIIQERSRELAVLETLDNGKPIRETRDADLPLVAAHFFYYAGWADKLDHAGFGANPRPLGVAGQVIPWNFPLLMLAWKIAPALATGNTVVLKPAETTPLSALFFADICRQAGLPRGVVNIVTGDGRAGAALVAHPGVDKVAFTGSTAVGKEIARTVAGTRKKLTLELGGKGANIVFDDAPIDQAVEGIVSGIFFNQGQVCCAGSRLLVQESIHDELLDSLKRRLSTLRLGDPLDKNTDIGAINSAEQLARITALADQGEAEGAERWSPACELPQNGFWFAPTLFTNVTQAHTIARDEIFGPVLSVLTFRTPDEAVAKANNTPYGLSAGIWTEKGSRILAVANKLRAGVVWSNTFNKFDPTSPFGGYKESGFGREGGRHGLEAYLDV
>NZ_CP010849.1|WP_044383398.1|4833453_4834416_-|deoxyribose-phosphate-aldolase
MSTNAPTAVHALSDVAASDSTLRRFLHGLPGVDAVGLEARAASLGTRSIKTTAKAYALDLAISMVDLTTLEGADTPGKVRALGAKAVRPDPTDRTAPSTAAVCVYPDMVATAKEAVAGSGVKVASVATAFPAGRAPLSVKLADVREAVAAGADEIDMVIDRGAFLAGNYRKVYDEIVAVKEACGTSARLKVIFETGELSTYDNIRRASWLGMLAGADFIKTSTGKVAVNATPANTLLMLEAVRDFRAQTGVQVGVKPAGGIRTAKDAIKFLVLVNETAGQDWLDNHWFRFGASSLLNDLLMQRQKLATGRYSGPDYVTVD
>NZ_CP010849.1|WP_044388248.1|4834707_4835397_+|PH-domain-containing-protein
MTTPEHQSSAPQPPVPATRDRVYRSPGGIAGGVLLLAVIGWLGIDAVVSGEGRTPWLALAVLLLLVPLVVAFTLRPAVFAGEDRLRVRNPLRVVVLPWGQVASLRSGYTNEVVAASGTKYQLWAIPVSLRARKKAARQEARRAAGGGRGRGGVLGGMGQGAFGGAGAAAVQDGPVRAETDQAMDDLRALRDAREKARSAQGEVTVRWAYEIAGPAVAGAVLLAVLLAVG
>NZ_CP010849.1|WP_052808648.1|4835542_4836760_-|hypothetical-protein
MSSTAPGTKQSGRIPGTRRPHAPRAVAPAARRALVRRVAHALRRAAPALAAYVAVRATGLLVLALWAHRQRRELWPILAAQWDADWYLGIAEHGYAHELGTAYNANNLAFFPLYPFLVKAVAVLTPGSRASTGLGIAVLASLLAAWGIFAVGDRLYGRRTGVLLTTLWAAFPVGAVQWMGYTESLFTACAAWSLYAVLTGRWLWAGALAALAGLTRPTGVAVAVAVGVAALWSLRRRPRRRRALIAAGLAPLGWCAFVGWVGLRLGRWDGYFAVQRLWHNELDGGVRTLHQVRQFLAYDPTPHLFLVVVTLTLIGAVVLFGLSLWDRQPLPLLVFTGVLLVIVLASGGVYFPRARFLIPAFPLLLPLALHLSRASHRHRTLALAAAVLGSAYCGAHMLLVWPSAP
>NZ_CP010849.1|WP_044383399.1|4836925_4838572_-|phospho-sugar-mutase
MHDELIARAKAWLAEDPDADTREELARLIDAGDHAELAARFGGTLQFGTAGLRGELGAGPMRMNRAVVIRAAAGLAAYLKKQGTPHGDGTAGLVVIGYDARHKSADFARDTAAVMTGAGLRAAVLPRPLPTPVLAFAIRHLGAVAGVEVTASHNPPRDNGYKVYLGDGSQIVPPADTDIAAEIDAVGSLHDVPRPATGWDTLDDSVLDAYLARTDAVLDPGSPRTARTVYTAMHGVGKDVLLAAFARAGFPEPVLVAEQAEPDPDFPTVAFPNPEEPGAMDLAFAKARETDPDLVIANDPDADRCAVAVKDGDGWRMLRGDEVGALLAAHLVTRGARGTFAESIVSSALLGKIAAKAGLPHEETLTGFKWIARVDGLRYGYEEALGYCVDPDGVRDKDGITAALLVTELASVLKSRGRTLLDLLDDLAVEHGLHATDQLSVRVQDLSVIADAMRRLREQPPTRLAGLPVTKAEDLTRGTQTLPPTDGLRYTLDGARVIVRPSGTEPKLKCYLEVTVPVAAHDGLPAARAKAADLLTALKRDLSAAAGI
>NZ_CP010849.1|WP_029383417.1|4839044_4839869_-|purine-nucleoside-phosphorylase
MNASLLPDDIQGDPYAAADAAAARLRELTGADTHDVALVMGSGWAPAVDALGAPDAEFQVTDLPGFPPPAVAGHGGKIRSYTIGEKRALVFLGRTHYYEGRGVAAVAHGVRTAVSAGCKTVVLTNGCGGLREGMRPGQPVLISDHINLTATSPIVGANFVDLTDLYSPRLRALCKEVDPTLEEGVYAQFPGPHYETPAEIRMARVIGADLVGMSTVLEAIAAREAGAEVLGISLVTNLAAGMTGEPLNHEEVLQAGRDSATRMGSLLARVLVRL
>NZ_CP010849.1|WP_029383416.1|4839961_4840399_-|gamma-glutamylcyclotransferase
MSLYAAYAGNLDARLMSRRAPHSPLRATGWLNGWRLTFGGEDMGWEGALATIVEDPTAQVFVALYDIAPMDEEAMDRWVGVGLDIYRRTRVRAHTLEGEEHAWAYVLNAYEGGLPSARYLGELADAAESAGAPYDYVMDLRKRPC

Crispr_ID: NZ_CP010849_16

• CRISPR_ID: NZ_CP010849_16
• CRISPR_location: 4941658-4941959
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP010849_16

Consensus_repeat	Method
CGGTCTTCGGCAGCGTCGAGATC	CRISPRCasFinder

spacers of NZ_CP010849_16

>16.1|4941681|40|NZ_CP010849|CRISPRCasFinder
AAGGGCCGCTGGCGGGCGGGCCGCCGGATCCACGCCTGGG
>16.2|4941744|52|NZ_CP010849|CRISPRCasFinder
GACCTCAGCGAGGCGATCTTCGAGTACCAGCAGGTGGTGGTGAAGGCGTTCT
>16.3|4941819|40|NZ_CP010849|CRISPRCasFinder
CGCGTCCCGGAGAACGTGTCGCTGCGCGGCATGGGCGGCG
>16.4|4941882|55|NZ_CP010849|CRISPRCasFinder
GACACCCTCGACTCGGCCGACGCCGAGGCGCCCGTCGTCTACATCGACGGCTGGG

CRISPR arrays and Neighbor proteins around NZ_CP010849_16

CRISPR arrays

The CRISPR arrays of NZ_CP010849_16

>merge|NZ_CP010849|16|4941658-4941959|CRISPRCasFinder
CGGTCTTCAGCGGCGCCGTGCGCAAGGGCCGCTGGCGGGCGGGCCGCCGGATCCACGCCTGGGCGGTCTTCGGCAGCGTCGAGATCGACCTCAGCGAGGCGATCTTCGAGTACCAGCAGGTGGTGGTGAAGGCGTTCTCGGTCTTCGGCAGCGTCGAGGTCCGCGTCCCGGAGAACGTGTCGCTGCGCGGCATGGGCGGCGGCGTCCTGGGCAGCTTCGAGGTGGACACCCTCGACTCGGCCGACGCCGAGGCGCCCGTCGTCTACATCGACGGCTGGGCCGTGCTGGGCAGCGTCGAGGCG

>NZ_CP010849|16|15|4941658-4941959|CRISPRCasFinder
CGGTCTTCAGCGGCGCCGTGCGC	AAGGGCCGCTGGCGGGCGGGCCGCCGGATCCACGCCTGGG
CGGTCTTCGGCAGCGTCGAGATC	GACCTCAGCGAGGCGATCTTCGAGTACCAGCAGGTGGTGGTGAAGGCGTTCT
CGGTCTTCGGCAGCGTCGAGGTC	CGCGTCCCGGAGAACGTGTCGCTGCGCGGCATGGGCGGCG
GCGTCCTGGGCAGCTTCGAGGTG	GACACCCTCGACTCGGCCGACGCCGAGGCGCCCGTCGTCTACATCGACGGCTGGG
CCGTGCTGGGCAGCGTCGAGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044383491.1|4945553_4945817_-|exodeoxyribonuclease-VII-small-subunit	unknown	unknown	gnl|CDD|179195
NZ_CP010849.1|WP_078648063.1|4948621_4949632_+|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	unknown	unknown	gnl|CDD|234893
NZ_CP010849.1|WP_044383494.1|4949713_4950478_+|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP010849.1|WP_044383482.1|4934639_4936706_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP010849.1|WP_044383489.1|4944487_4945078_-|malonic-semialdehyde-reductase	unknown	unknown	gnl|CDD|180040
NZ_CP010849.1|WP_044383488.1|4943840_4944401_+|DUF4245-domain-containing-protein	unknown	unknown	gnl|CDD|379430
NZ_CP010849.1|WP_029381827.1|4942213_4942588_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP010849.1|WP_044383480.1|4930777_4931047_-|hypothetical-protein	unknown	unknown	gnl|CDD|227214
NZ_CP010849.1|WP_044383478.1|4929318_4930005_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP010849.1|WP_044383483.1|4936987_4937680_-|DUF402-domain-containing-protein	unknown	unknown	gnl|CDD|377233
NZ_CP010849.1|WP_044383492.1|4945826_4947035_-|exodeoxyribonuclease-VII-large-subunit	unknown	unknown	gnl|CDD|272979
NZ_CP010849.1|WP_044383493.1|4947083_4948484_-|APC-family-permease	unknown	unknown	gnl|CDD|223605
NZ_CP010849.1|WP_044383479.1|4930001_4930526_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP010849.1|WP_044383484.1|4937820_4939236_-|class-II-fumarate-hydratase	unknown	unknown	gnl|CDD|234779
NZ_CP010849.1|WP_044383485.1|4939313_4940990_-|fumarate-hydratase	unknown	unknown	gnl|CDD|237955
NZ_CP010849.1|WP_044383481.1|4931043_4931979_-|SPFH-domain-containing-protein	unknown	unknown	gnl|CDD|259800
NZ_CP010849.1|WP_044383477.1|4926988_4929322_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|376899
NZ_CP010849.1|WP_044388273.1|4932252_4934544_+|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NZ_CP010849.1|WP_044383490.1|4945303_4945549_+|DUF4287-domain-containing-protein	unknown	unknown	gnl|CDD|379478
NZ_CP010849.1|WP_044383487.1|4942678_4943713_-|class-II-fructose-bisphosphatase	unknown	unknown	gnl|CDD|236536

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044383491.1|4945553_4945817_-|exodeoxyribonuclease-VII-small-subunit	gnl|CDD|179195	PRK00977, PRK00977, exodeoxyribonuclease VII small subunit; Provisional.	2.84336e-17
NZ_CP010849.1|WP_078648063.1|4948621_4949632_+|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	gnl|CDD|234893	PRK01045, ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed.	0
NZ_CP010849.1|WP_044383494.1|4949713_4950478_+|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	9.30518e-35
NZ_CP010849.1|WP_044383482.1|4934639_4936706_-|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	3.12281e-52
NZ_CP010849.1|WP_044383489.1|4944487_4945078_-|malonic-semialdehyde-reductase	gnl|CDD|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	1.13638e-106
NZ_CP010849.1|WP_044383488.1|4943840_4944401_+|DUF4245-domain-containing-protein	gnl|CDD|379430	pfam14030, DUF4245, Protein of unknown function (DUF4245). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 188 and 235 amino acids in length.	2.80357e-52
NZ_CP010849.1|WP_029381827.1|4942213_4942588_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	5.2708e-20
NZ_CP010849.1|WP_044383480.1|4930777_4931047_-|hypothetical-protein	gnl|CDD|227214	COG4877, COG4877, Uncharacterized protein conserved in bacteria [Function unknown].	3.53591e-14
NZ_CP010849.1|WP_044383478.1|4929318_4930005_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	4.42583e-99
NZ_CP010849.1|WP_044383483.1|4936987_4937680_-|DUF402-domain-containing-protein	gnl|CDD|377233	pfam04167, DUF402, Protein of unknown function (DUF402). Family member FomD is a predicted protein from a fosfomycin biosynthesis gene cluster in Streptomyces wedmorensis. Its function is unknown.	9.17516e-18
NZ_CP010849.1|WP_044383492.1|4945826_4947035_-|exodeoxyribonuclease-VII-large-subunit	gnl|CDD|272979	TIGR00237, exodeoxyribonuclease_VII_large_subunit, exodeoxyribonuclease VII, large subunit. This family consist of exodeoxyribonuclease VII, large subunit XseA which catalyses exonucleolytic cleavage in either the 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. Exonuclease VII consists of one large subunit and four small subunits. [DNA metabolism, Degradation of DNA].	1.94964e-159
NZ_CP010849.1|WP_044383493.1|4947083_4948484_-|APC-family-permease	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	1.50416e-37
NZ_CP010849.1|WP_044383479.1|4930001_4930526_-|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	8.71637e-16
NZ_CP010849.1|WP_044383484.1|4937820_4939236_-|class-II-fumarate-hydratase	gnl|CDD|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP010849.1|WP_044383485.1|4939313_4940990_-|fumarate-hydratase	gnl|CDD|237955	PRK15389, PRK15389, fumarate hydratase; Provisional.	0
NZ_CP010849.1|WP_044383481.1|4931043_4931979_-|SPFH-domain-containing-protein	gnl|CDD|259800	cd03402, SPFH_like_u2, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease, and in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	2.65766e-128
NZ_CP010849.1|WP_044383477.1|4926988_4929322_-|ABC-transporter-permease	gnl|CDD|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	5.33077e-05
NZ_CP010849.1|WP_044388273.1|4932252_4934544_+|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	3.63567e-134
NZ_CP010849.1|WP_044383490.1|4945303_4945549_+|DUF4287-domain-containing-protein	gnl|CDD|379478	pfam14117, DUF4287, Domain of unknown function (DUF4287). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 70 and 180 amino acids in length.	5.03495e-27
NZ_CP010849.1|WP_044383487.1|4942678_4943713_-|class-II-fructose-bisphosphatase	gnl|CDD|236536	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed.	0

Protein sequences

>NZ_CP010849.1|WP_044383485.1|4939313_4940990_-|fumarate-hydratase
MGEMPEFAYTDLLPVGEDTTPYRLVTSEGVSTVEGPDGRTFLKVEPEALRKLAEEAIHDIQHYLRPAHLAQLRRIIDDPEASSNDKFVALDLLKNANIAAAGVLPMCQDTGTAIVMGKRGQNVLTAGRDEEALSRGIYDAYTRLNLRYSQMAPLTMWEEKNTGSNLPAQIELYATDGDAYKFLFMAKGGGSANKSFLYQETKAVLNETSMMKFLEEKIRSLGTAACPPYHLAIVVGGTSAEYALKTAKYASAHYLDDMPTEGSPLGHGFRDKELEEKVFELTQKIGIGAQFGGKYFCHDVRVIRLPRHGASCPVALAVSCSADRQAVAKITAEGVFLEQLETDPARFLPDTTDAQLDEGDVVRIDLNQPMEQILAELTKYPVKTRLSLTGPLVVARDIAHAKIKERLDAGEEMPQYLKDHPVYYAGPAKTPEGYASGSFGPTTAGRMDSYVEQFQAAGGSKVMLAKGNRSKQVTDACAAHGGFYLGSIGGPAARLAQDCIKKVEVLEYEELGMEAVWKIEVEDFPAFIVVDDKGNDFFQDPAPAPTFTSIPVRGPGLG
>NZ_CP010849.1|WP_044383484.1|4937820_4939236_-|class-II-fumarate-hydratase
MTDEGQDSADRTGYRIEHDSMGEVRVPAHAKWRAQTQRAVENFPVSGQRIERAHIEALARIKGAAAKVNAELGVLDREIAEAIQEAAAEVAAGRWDDHFPVDVFQTGSGTSSNMNANEVVATLASERLGRDVHPNDHVNASQSSNDVFPSSIHIAATAAVTRDLIPALEHLAAALERKAADFADVVKAGRTHLMDATPVTLGQEFGGYAAQVRYGVERLRASLPRLAELPLGGTAVGTGINTPPGFSAAVIAEVARATGLPLTEARDHFEAQGARDGIVETSGQLRTVAVGLTKIANDLRWMSSGPRTGLAEITLPDLQPGSSIMPGKVNPVIPEAVLMVCAQVIGNDATVATAGAAGNFELNVMLPVIAKNVLESIRLLANVSRLLADRTVDGVVAQRERAREYAESSPSVVTPLNRYIGYEEAAKVAKRALAERKTIRQIVLEGGYVDRGDLTEEQLDEALDVLRMTRP
>NZ_CP010849.1|WP_044383483.1|4936987_4937680_-|DUF402-domain-containing-protein
MTDGEAVTAAARADGTAFWKPGSQILWRYRENGGTRIHIARPVTVVRDDAEVLAAWMAPGTECVKPVLADGTPVHQEPLASRYTKPRTVLRDRWFGTGVLKLARPGEPWSVWLFWEPGWRFKNGYVNLEEPLARWSGGVDSEDHFLDITVQPDGSWHWRDEDEFAQAQRDGLMDARLAERVRRAGRSAVEVIRAWGPPFSDGWQDWRPDPSWPVPSLPKDWDRTPAHVSS
>NZ_CP010849.1|WP_044383482.1|4934639_4936706_-|SpoIIE-family-protein-phosphatase
MDSTRVTEYPTSFERPTAGVDPADPRGALLHTPAPAHTPGATALPAPSAQGRAGETPAGPTTGPDGVFEHSQPAAGQAAEPDHRPRPVPETIPAQPGGDTDPAAGPERRTGQVPAPGRPTPMRRDGDRLRFVGAATRRIARGMDLDEIVMGLCRATVPTFADAILVYLREPLPVGDERPSGPLVLRLRRTDRIPADRDTEGGFMPAVQPEPSELDTVGSELCEVRPGSALAEVLRGVRPVFTDAPAARAALPELLGEGGEFAVPGGQRAILAPLRGRRRVIGAALFLRGPERIAFETDDLLVAAQLATHSALGIDKAVLYGREAYIADELQRTMLPENLPRCTGVRLASRYLPAAETARVGGDWYDAIPLPGSRVALVVGDVMGHSMTSAAIMGQLRTTAQTLAGLDLPPQEVLHHLDEQAQRLGTDRMATCLYAVYDPVAHRITVANAGHPPPVLLHLGGRAEVLSVPAGAPIGVGGVDFEAVELDAPAGGTLLLYTDGLVESRLRDVWTGIEQLREKLEATAELTGADHAPPLEALCDEVLDMLGPGDRDDDIALLAARFDGIAPSDVAYWELEPEDAAPGRARRLARRELARWGLEDLTDSVELLVSEVVTNAVRYASRPVTLRLLRTDVLRCEVGDDVPQLPRLRQARATDEGGRGLYLVNRMARRWGATRLSTGKVVWFELNR
>NZ_CP010849.1|WP_044388273.1|4932252_4934544_+|penicillin-binding-protein
MGRAEERRARQRGGRRAAPKRRRSSGAAGKSGIGRLFTWKKILGTFFGLCLLGMGAFIVLYLVIDIPEGNADAKLQSNVYKYSDGSVMTRDGDRNREIVDLAKVPKDVQHTFVAAENKTFYKDAGVDLKGTARGVLNTLAGKGAQGGSTITQQYVKNYYLTQDQTVSRKLKELVISLKLDREKSKDYILAGYINTSYYGRGAYGIQAAAQAYYRVDAEDLTVEQGAYLAALLQAPNQYDWAIASDTGKKLVRERWNYVLDNMVEQDWLDAAERRAMTFPVPEEPKPDPGMGGQTGYLVDAANAALERQLVAQGSAEDMKQAQAMVDAGGWTLTLNIDKKKQAALERSVKTQLTGKLNPGENEADARVQAGAVSVDPRTGAVVAMYGGTDYLKHFTNNATRDDYQPASTFKPVILAAAVDEDATTQDGTPITANTLYDGTSKRPVVDHGRKVGFAPENEDDVDYGDITVQQAMNQSVNSVFAQMGVDVGMDEVVEVAGKLGMETEGMDAVPAQTLGSMGASPLEMAGVYATLDNHGKKVTPALVKSVEHNSRRVEFPDPVGEQVISREAADTVTSVLTGVVDDGTARTSVRENPLRGGQQVAGKTGTSDNNKSAWFTGYTPDLVTSVGLFGEDPKTYAQVPLYGAVGEERLNGGEYPAQIWAAYTFGVMDGISRFDLETKQGAAVQPTRTPTPTRQPSRTPTEEPTTREPTSAPPTSETPSPTPTTQSPSPTPTTQSPSPTPTTPSPTVEEPENPFFPEDDDER
>NZ_CP010849.1|WP_044383481.1|4931043_4931979_-|SPFH-domain-containing-protein
MSTHHAQAAADVPEMPAPRVREFPAHSIGGGLALLLGLVGLLAGVGMVVAATAVTAGGAKAVLIVAGVLVALAAFVAVCGLNMVAPGEARVVQLFGRYRGTIRQDGLRWVNPLTSRTKISTRVRNHETAVLKVNDAYGNPIELAAVVVWRVEDTAQATFEVDDYIEFVSTQTEAAVRHIAIEYPYDAHEEDGLSLRGNAEEITEKLAVELHARVEAAGVQIIESRFTHLAYAPEIASAMLQRQQAGAVVAARRQIVDGAVGMVEAALARIAQQDIVELDDDRKAAMVSNLMVVLCGDRSAQPVLNTGTLYQ
>NZ_CP010849.1|WP_044383480.1|4930777_4931047_-|hypothetical-protein
MTAPSGDPAPRRRPQQRKQVLLRLDPLVYEALARWAGDELRSANAQIEFLLRRALAEAGRLPGGTGPIPRRGRPPADPAAADRPAEPEG
>NZ_CP010849.1|WP_044383479.1|4930001_4930526_-|PadR-family-transcriptional-regulator
MSIGHTLLGLLESGPRHGYDLKRAFDEKFGHDRPLHYGQVYSTMSRLLKHGLVEVDGIEAGGGPERKRYAITDAGITDVEQWLATPEKPEPYLQSTLYTKVVLALLTRRDAAEILDTQRSEHLRGMRILTDRKRKGDLADQLICDHALFHLEADLRWLELTAARLDKLREAVTR
>NZ_CP010849.1|WP_044383478.1|4929318_4930005_-|ABC-transporter-ATP-binding-protein
MTPPGSLLAAERLHKAYGPTVALDGAGFSIHPGEIVAVMGPSGSGKSTLLHCLAGIVTPDSGTITYDGRELSAMNDAQRSALRRSEFGFVFQFGQLVPELTCVENVALPLRLNGTPRKEAERAALSWLERLEVDDLRKKRPGEVSGGQGQRVAVARALVTRPRVLFADEPTGALDSLNGERVMELLTEAARATNAAVVLVTHEARVAAYSDREIVVRDGRSRDMEHAI
>NZ_CP010849.1|WP_044383477.1|4926988_4929322_-|ABC-transporter-permease
MSARRWARDLAQGVRFAFAGGREGWVRALLTAVGVGLGVALLLLTTAIPNALAVRHDREMARSDDLVVDARIPPAADTVVVAHVDTDFGDRTVRGRALEPEGPRAPLPPGVDRFPAVGEMVVSPALKELLDADSGKLLRERLPDRVVGTIGESGLIGSAELAFYRGGEDLASYIDDARATRIDRFGFSGSPSEPMDPVLLLLVLVVFVVLLMPVAVFIAAAVRFGGERRDRRLAALRLVGADGRTTRRIAAGEALAGAALGLVFGAVFFLIGREVAGGVEVYRVSVFPSYLNPSPLLALLVAVAVPAAAVLVTLLALRGVVIEPLGVVRAAKPARRRLWWRLLLPLAGLVMLYPMVGKGRGNGEFNQYLVVGGVVLLLVGVTALLPWVVEAVVARLGAGTVSWQLAVRRLQLSSGTAARMVNGIAVAVAGAIALQMLFAGVDDDYTRDTGHDLTRAQMQVDVVRTVPLESAAEKLRRTEGVRAAYAYAEGMTGDRRTEPGATTWVTAGDCAALREVATLPSCRDGDVFAVSGVEYDTDTPKLAVPGRTLYLDPSYESGPKRATVAWRVPRDLKEARPRTWLTGSERGGFLVTWGALPAGAGAALYQEVYLALDPSAHDAQERVRNTAAALHPMTSTMTWAATERSGRFASLRTGLFAGAVCVLALIGASLLVSQLEQLRERRKLLSSLVAFGTRRRTLSLSVLWQTAVPIALGLLLASVVGLTLGAVLLKMTATPVRVDWTSVLSMTGIGAAVVLVVTLLSLPPLLRLMRPDGLRTE
>NZ_CP010849.1|WP_029381827.1|4942213_4942588_+|WhiB-family-transcriptional-regulator
MLQPPHSSLQVAAVPAQRVPVRDRDHDAPWHTEAVCRRDEAGLFFAPSKEPTAARLSREEAAKRVCARCPVMVECREHALLQPEPYGVWGGLTAAERRVVLARRRRRELELKKARAAGRIAAAG
>NZ_CP010849.1|WP_044383487.1|4942678_4943713_-|class-II-fructose-bisphosphatase
MTEHHHLPSELDVPSEAPDRNLAMELVRVTEAAAMAAGRWVGRGDKNGADGAAVRAMRTLVHTVSMNGVVVIGEGEKDEAPMLFNGEHVGDGTGPECDIAVDPIDGTTLTAKGMPNAIAVLAAAERGSMFDPSAVFYMDKLVTGPEAADFVDIDAPVAVNIRRVAKAKRSTPEDVTVCILDRPRHQELIDQVRQTGARIKLISDGDVAGSILALREGTGIDLLLGIGGTPEGIISACAVKCLGGTIQGKLWPKDDEERQRAIDAGHDLDRVLTTDDLVASDNVFFAATGITDGELLRGVRYRSETATTSSIVMRSKSGTVRRVDSEHRLSKLRAYSAIDFDRAK
>NZ_CP010849.1|WP_044383488.1|4943840_4944401_+|DUF4245-domain-containing-protein
MAGTNGKQKTARDMILSLAVIVLVGGVMWLFIPHDDDAEPDIKRVDYRVELLTARRAASYPVAAPEGLPEAWKPTSVRFRGDDFDRWHLGYHAPDGEYVAVEQSTEKASRFIDEASQGARETEVTQEIGGRTWVRYTGGRYDALVLKDTGGTGEADGENAGRATTVVAGTGSFGQLTKMAAALKME
>NZ_CP010849.1|WP_044383489.1|4944487_4945078_-|malonic-semialdehyde-reductase
MSLVLDPAAQDLLFREARTANTFTDEPVTDEQVQAIYDLVKYGPTAFNQSPLRITLVRSPEARERLVRHMAEGNQPKTATAPLVAILSADNEFHEELPELFPHFPQAKDVFFGERPVRENAAALNAALQAAYFIVGVRAAGLAAGPMTGFDYEGVRKEFLDDDHTPLMIVNIGKPGPDAWYPRSPRLAYDQVVTTV
>NZ_CP010849.1|WP_044383490.1|4945303_4945549_+|DUF4287-domain-containing-protein
MTDTAQPATPAAKSGVKGPAAYFPSIEKKYGRPVTEWKELVRASPLTRHMELVTWLKTEHGLGHGHANALVAHTLAEDSGK
>NZ_CP010849.1|WP_044383491.1|4945553_4945817_-|exodeoxyribonuclease-VII-small-subunit
MTSEVDETAARTEALGYEQARDELIEVVRRLEAGGTTLEESLALWERGEELAKICRRRLDGARARLDAALAEEDAERAGERDAPEAS
>NZ_CP010849.1|WP_044383492.1|4945826_4947035_-|exodeoxyribonuclease-VII-large-subunit
MAVNTTPESPLPVGEVSRLIGGWIDRLGAVWVEGQITQLSRRPGAGVVFLTLRDPSYDISVSVTCYRQVFDAVADVVGEGARVVVHAKPEWYAPRGQLSLRAAEIKPVGVGELLARLEQLKKSLAREGLFAPERKKPLPFLPHLVGLVCGRASAAERDVLENARHRWPAVRFEVRNVAVQGVHAVPQVVQAVKELDGIDEVDVIIVARGGGSVEDLLPFSDEQLVRAVAACRTPVVSAIGHEPDTPLLDYVADVRASTPTDAAKKVVPDVGEEYERVRLLRDRARRCVRALVEREERGLAHALARPSVQDPHRMIDERAEQVASLLDRGRRTLRHHLDRADSELTHTHARVVALSPAATLKRGYAVLQRADGHAVRDPGEVAAGEALRARVSEGEFSVRVDA
>NZ_CP010849.1|WP_044383493.1|4947083_4948484_-|APC-family-permease
MSERSGTSGTGTADRDGGDGQELRRNLGFRDLVVYGLLFIAPMAPVGVFGTLDAKSHGAVALVYVVATVAMAFTAFSYAQMVRVVPQAGSVFAYARAGLGEGAGFVAGWMAALDYVLIPAVAYLFSGIAMNELVPGVSRWVWTALAVVITTLLNLWGVRAAARVGFLVLAMEIAVLLVFVVAALVVLARDGAERGWLSPLTGDGSQGAFALSAVIGAVSVAVLSYLGFDAIATFAEEATGGSHRVARALLFCLALAGLLFVAQTYLVALLEPVPSARLAAEPERQGSAFYDAVEASVGTWLQDLVAVSKAIGAAFAALAGQAAAGRLLFAMGRDRRLPRALARTSSGVPRVALLCAALITLVAAVWAARRDDGLDHLVSVVDIGALTAFTLLHASVVGWFAVRRRGAAVSWWRHVLLPVVGALITVAVIVGASGTAQVVGALWLAAGLVVLVVQSRGRGRGPAGAG
>NZ_CP010849.1|WP_078648063.1|4948621_4949632_+|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase
MTASPGRRVLLAAPRGYCAGVDRAVIAVEKALEQYGAPIYVRHEIVHNKYVVQTLEKKGAVFVERTEEVPPGNIVMFSAHGVAPVVHEEAERGRLATIDATCPLVTKVHKEAVRFAKEDYDILLIGHEGHEEVIGTSGEAPDHIQLVDGPGDVAKVEVRDPSKVVWLSQTTLSVDETMETVDALKEKFPQLLSPPSDDICYATQNRQLAVKQMGAEADLVIVVGSRNSSNSKRLVEVAKQAGARAAYLVDFADEIDETWLEGVATVGVTSGASVPEVLVEQVLEWLARRGFEDVEIVKAAEESITFSLPKELRRDLRDEAAALVAERGGAGASGAE
>NZ_CP010849.1|WP_044383494.1|4949713_4950478_+|ROK-family-protein
MQIFGVDIGGSGIKGAPVDLDKGDLAQERCKVLTPHPATPDRVADGVKQVVDHFGWTGPVGLTFPGVVTGGATVRTAANVDSAWIDTDARALFGDRLGGLPVTVVNDADAAGVAEMHFGAGRGRRGTVIVLTFGTGIGSAVFTDGVLVPNTELGHLELDGHDAEKRASSKVKEDQDLSWEQWAHRVGRYLSHVEMLFSPELFIIGGGVSRKSRKFLHCIEGVKAEIVPAQLQNNAGIVGAAMRAAGAGETTAAG

Crispr_ID: NZ_CP010849_17

• CRISPR_ID: NZ_CP010849_17
• CRISPR_location: 5043666-5043765
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_17

Consensus_repeat	Method
CCGTCCGGTCCTGGCTCCTCCCCGG	CRISPRCasFinder

spacers of NZ_CP010849_17

>17.1|5043691|50|NZ_CP010849|CRISPRCasFinder
GTCGCTCCGGTGTTCCATTCGGTCCCGGCTCCCCGGACTGCCCCGTTGTT

CRISPR arrays and Neighbor proteins around NZ_CP010849_17

CRISPR arrays

The CRISPR arrays of NZ_CP010849_17

>merge|NZ_CP010849|17|5043666-5043765|CRISPRCasFinder
CCGTCCGGTCCTGGCTCCTCCCCGGGTCGCTCCGGTGTTCCATTCGGTCCCGGCTCCCCGGACTGCCCCGTTGTTCCGTCCGGTCCTGGCTCCTCCCCGG

>NZ_CP010849|17|16|5043666-5043765|CRISPRCasFinder
CCGTCCGGTCCTGGCTCCTCCCCGG	GTCGCTCCGGTGTTCCATTCGGTCCCGGCTCCCCGGACTGCCCCGTTGTT
CCGTCCGGTCCTGGCTCCTCCCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044383604.1|5046418_5047216_+|phage-related-protein,-tail-component	unknown	unknown	gnl|CDD|371915
NZ_CP010849.1|WP_044388290.1|5035703_5036459_+|hypothetical-protein	unknown	unknown	gnl|CDD|205967
NZ_CP010849.1|WP_044383602.1|5045339_5046431_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|366597
NZ_CP010849.1|WP_044383600.1|5043920_5044988_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044383598.1|5041893_5043597_+|DUF3492-domain-containing-protein	unknown	unknown	gnl|CDD|340841
NZ_CP010849.1|WP_044383616.1|5055657_5056044_+|DNA-binding-protein	unknown	unknown	gnl|CDD|226219
NZ_CP010849.1|WP_044383614.1|5052732_5055471_-|membrane-protein	unknown	unknown	gnl|CDD|377103
NZ_CP010849.1|WP_044383596.1|5039922_5041554_+|DUF3152-domain-containing-protein	unknown	unknown	gnl|CDD|371483
NZ_CP010849.1|WP_044383606.1|5047279_5048458_+|adenylyltransferase/sulfurtransferase-MoeZ	unknown	unknown	gnl|CDD|181156
NZ_CP010849.1|WP_044383594.1|5038891_5039914_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP010849.1|WP_044383610.1|5049378_5050953_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|312032
NZ_CP010849.1|WP_162487305.1|5032624_5035369_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NZ_CP010849.1|WP_078969274.1|5056319_5059673_+|ATP-dependent-helicase	unknown	unknown	gnl|CDD|223288
NZ_CP010849.1|WP_044383608.1|5048667_5048976_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_029386342.1|5037438_5038083_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP010849.1|WP_044383591.1|5038317_5038542_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_029386341.1|5037065_5037293_-|DUF3107-domain-containing-protein	unknown	unknown	gnl|CDD|378634
NZ_CP010849.1|WP_044383612.1|5051096_5052635_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|312032
NZ_CP010849.1|WP_044383582.1|5031618_5032527_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP010849.1|WP_044383587.1|5036560_5036830_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044383604.1|5046418_5047216_+|phage-related-protein,-tail-component	gnl|CDD|371915	pfam12138, Spherulin4, Spherulation-specific family 4. This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 250 and 398 amino acids in length. There is a conserved NPG sequence motif and there are two completely conserved G residues that may be functionally important. Starvation will often induce spherulation - the production of spores - and this process may involve DNA-methylation. Changes in the methylation of spherulin4 are associated with the formation of spherules, but these changes are probably transient. Methylation of the gene accompanies its transcriptional activation, and spherulin4 mRNA is only detectable in late spherulating cultures and mature spherules. It is a spherulation-specific protein.	9.07107e-27
NZ_CP010849.1|WP_044388290.1|5035703_5036459_+|hypothetical-protein	gnl|CDD|205967	pfam13794, MiaE_2, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like.	1.16545e-92
NZ_CP010849.1|WP_044383602.1|5045339_5046431_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|366597	pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilize NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.	1.73588e-39
NZ_CP010849.1|WP_044383598.1|5041893_5043597_+|DUF3492-domain-containing-protein	gnl|CDD|340841	cd03813, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.	3.04792e-165
NZ_CP010849.1|WP_044383616.1|5055657_5056044_+|DNA-binding-protein	gnl|CDD|226219	COG3695, COG3695, Predicted methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	2.22793e-18
NZ_CP010849.1|WP_044383614.1|5052732_5055471_-|membrane-protein	gnl|CDD|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	1.79025e-29
NZ_CP010849.1|WP_044383596.1|5039922_5041554_+|DUF3152-domain-containing-protein	gnl|CDD|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	3.53505e-70
NZ_CP010849.1|WP_044383606.1|5047279_5048458_+|adenylyltransferase/sulfurtransferase-MoeZ	gnl|CDD|181156	PRK07878, PRK07878, molybdopterin biosynthesis-like protein MoeZ; Validated.	0
NZ_CP010849.1|WP_044383594.1|5038891_5039914_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	8.30585e-28
NZ_CP010849.1|WP_044383610.1|5049378_5050953_-|alpha/beta-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	7.15842e-35
NZ_CP010849.1|WP_162487305.1|5032624_5035369_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	7.66197e-145
NZ_CP010849.1|WP_078969274.1|5056319_5059673_+|ATP-dependent-helicase	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.4294e-99
NZ_CP010849.1|WP_029386342.1|5037438_5038083_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.81353e-17
NZ_CP010849.1|WP_029386341.1|5037065_5037293_-|DUF3107-domain-containing-protein	gnl|CDD|378634	pfam11305, DUF3107, Protein of unknown function (DUF3107). Some members in this family of proteins are annotated as ATP-binding proteins however this cannot be confirmed. Currently no function is known.	3.19829e-36
NZ_CP010849.1|WP_044383612.1|5051096_5052635_-|alpha/beta-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	2.61969e-36
NZ_CP010849.1|WP_044383582.1|5031618_5032527_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.52506e-15

Protein sequences

>NZ_CP010849.1|WP_044383598.1|5041893_5043597_+|DUF3492-domain-containing-protein
MRIGLLTEGGYPYVSGDAGLWCDRLVRGLAQHEFDIYALCAGEHQENEGRVPLPPQVGRVRTAPLWGTEDDGVSYGRRARRRFAECYGELAAVLCADAPQEPSGAPRTSPLAQADRFANALYGLAELAREEGGPARALRSEQAVRALERACRAPGATRLARQARVADLLTTAAHLERILRPLSLDWYGQDGLGAVDLCHAASGGAAAVPGLLARHFSGVPLLVTEYGVRLRTHYLTAAGSSPAVRSLLAAFHGRLAAETYRQAALITPGNAHARRWQERCGADRARIRTVYPGMDASPFAEVGEAPERADPDTLVWAGPIEPAKDLVSLLHAFAEIRAHEPKARLRIVGTPAGPEGETYLHHCRELAELLFPDAARGPLAPGGPPVSFERTGGPEVPTSADAYAGGAVVVLSSAVEGFPSVLVEAMLCGRATVSTDVGAVREVIGGTGLVVPPDDPRALAEACVTLLRDPQRRARLGAAARARALELFTVEQNIAAFHGIYLEIVSRVPVRRVLLDDAGRPLPFAAPAEAHLPGHWSGTTSSAAARGGPRWATRPPVAVPAVTEGAR
>NZ_CP010849.1|WP_044383596.1|5039922_5041554_+|DUF3152-domain-containing-protein
MGRHSRRGPAPKGDTADTTGTAGSGPGAAQGTVPDGSPAPGAVPGPGTGRRRMTGPATPEQTPPPDGRTPPDGRTPPAGGPQGLAGARYPEGTAAHGLPRLADGTPARGVPRVRGGHPEQREVGGGWGELGRAGGPNMSPYGAPEGPGPLAEPGSPAEPDAPAGRRAPAGPGPGVVFPRQQQRHGRRQADPAGPRQAYLDAFDTADGGTPAPRSHRRPGMPAQAAGPDASVAGRDSGQGSGRGTVRGGATAAARGDDEPPTGAPAAAKDGKDAKGGKGRTFTGIAAAAVTTVLAVVVAGQAADGRGGQDARGQSAGDQARDARASASRADGRPTPSTSAGAAPLTYDQKMGRKYPLSATLDGPGTFQAVPGIAKAPGTGQKFTYRVDVEKGLGLDAELFAQAVQKTLNDDRSWAHNGARTFERIHSGRPDFVITLASPGTTADWCAKSGLDTTVDNVSCDSAATERVMINAYRWAQGSETYGDEIHAYRQMLINHEVGHRLGYSHVTCDKDGELAPVMQQQTKFLDPAEGIHCLPNAWPYPGR
>NZ_CP010849.1|WP_044383594.1|5038891_5039914_+|alpha/beta-hydrolase
MSSTELPFVPPADLLSKAAAVRVAEGERLRSVRLPGITLAVRSRPPAREGLPPALYVHGLGGSSQNWSALMPLLDDVTDNEAVDLPGFGDSPPPDDGNYSVTGHARAVIRYLDACGRGPVHLFGNSLGGAIVTRVAAVRPDLVRTLTLVSPALPEIRVQRTAVPTGLLAVPGVASLFTRFTREWTAEQRVRGVMALCYGDPGRVSPEGFRHAVEEMERRLGLPYFWDAMARSARGIVNAYTVGGQHGLWRQAERVLAPTLLVYGGRDRLVGYRMAQRAARAFRDSRLLTLPDAGHVAMMEYPETVATAFREFLADTGKSAAGTDTEGAADGVPANESTGG
>NZ_CP010849.1|WP_044383591.1|5038317_5038542_-|hypothetical-protein
MAVDPTDPETFEDEETREDQEFGVEAPEVDAAEQHADIAPHRDDPLTGVDPDRASEADLMEQTRIVTLDEDDYR
>NZ_CP010849.1|WP_029386342.1|5037438_5038083_-|TetR/AcrR-family-transcriptional-regulator
MTAIEQTEAVRPRGTRLPRRARRNQLLGAAQEVFVAQGYHAAAMDDIAERAGVSKPVLYQHFPGKLDLYLALLDQHCESLIQSVRNALASTSDNKQRVRATMDAYFAYVEDDGGAFRLVFESDLTNEPAVRERVDKVTNECAEAICDVIAEDTGLSRAESMLLASGLGGLAQVVARSWLHSDRSVPRDQAVQLLASLAWRGIAGFPLHGNDQHH
>NZ_CP010849.1|WP_029386341.1|5037065_5037293_-|DUF3107-domain-containing-protein
MEVKIGVQHAPREIVLESGQSAEEVERIVADALAGKAQLLSLVDEHGRKVLVPADRLAYVEIGEPAPRKVGFGAL
>NZ_CP010849.1|WP_044383587.1|5036560_5036830_-|hypothetical-protein
MLLEALSSFVLGLVLAGTAAHRLPHRLPARALVLPTGIAGSLFGAFVTHSALDAGSLPMVLLGAAAVSLAALSLLLRPAGRLGRRSATV
>NZ_CP010849.1|WP_044388290.1|5035703_5036459_+|hypothetical-protein
MTSSDKPGNAADAPAESTGATAVAALDWATAAADPQYRAAVVDLLGALAYGELAAFERLAEDAKLAPTLEDKAELAKMASAEFHHFERLRNRLAEIGEEPTGAMEPFVAAYEGFHKQTAPSDWLEGLVKAYVGDSIASDFYREVAARLDSDTRSLVLAVLDDTGHASFAVEKVRAAIDAEPRVGGRLALWARRLMGEALSQSQRVVADRDALSTMLVGGVADGFDLAEVGRMFSRITEAHTKRMAALGLAA
>NZ_CP010849.1|WP_162487305.1|5032624_5035369_-|DEAD/DEAH-box-helicase
MPTARPRGRPESPARSRDTTPALASRRTHRRGSTLTTTFRSLGILPETAEALEAVGIITPFPIQEMTLPVALSGSDVIGQAKTGTGKTLGFGLPLLERVTVPADVEAGRARPEALTDAPQALVVVPTRELCVQVTNDLLTAGKVRNVRVTAIYGGRAYEPQVEALKKGVDVVVGTPGRLLDLAGQKKLDLKHVKCLVLDEADEMLDLGFLPDVEKIIGMLPAKRQTMLFSATMPGAVIGLARRYMSRPTHIRATAPDDEGMTVANIKQFVYRAHSMDKPEMIARILQADGRGLAMIFCRTKRTAADIAEQLQRRGFAAGAVHGDLGQGAREQALRAFRNGKVDVLVCTDVAARGIDVEGVTHVINYQSPEDEKTYLHRVGRTGRAGAKGTAITFVDWDDIPRWQLINKALQLDFNDPVETYSSSPHLYSDLGIPEGTKGVLPRAARTRAGLDAEELEDLGEPGGRAGRGRGGRGDRDDRRDSRPDDRERSDRTPRRRRRTRGGTPLDAASPATTAPDAVTAGGTEGTAEEADKPGRTLRRRRRTRGGAVTRQPVTGATAEAAVTTAPPRETAPQATEAAPEAAPVASAEAPAQPRRRRTRKTAQPADAAAVTATEESPAAEIPASEATAAPAPLAEAATAPEAPAAKPRRRTRKAAATADAAVETAEATTETAEAKPRRTRKAAAKAETAETPEGAEAAEAKPRRTRKTAAKTETTADATAEATDTTEPKPRRTRKTAAKTETTADATAEATDTTEAKPRRTRKTAAKTETPETAEVAEVAEAKPRRTRKAAAKAETTDTAEATDTTEAKPRRTRKAAAKTETTGDTTAEATEAAETKPRRRARKATAEAEAVTAGIPAQATQEPEAAPRRRTRKAVAADAGESSGEAAEAKPKARRTRKATAAAAQPAESTEG
>NZ_CP010849.1|WP_044383582.1|5031618_5032527_-|alpha/beta-hydrolase
MSRNATFTPPPGARAYRLRTARGEFAVVDSPAAGGAEPKGLVLMLPGFTGSKEDFTLLHEPLAARGYRTVAVDGRGQYETDGPAHDESAYTQRELARDVLAQAAALDAPVHLLGHSLGGQIARAAVLLDHSPFRSLTLLSSGPAQISVSQQERVKLLRDALAVLTMEQVWETMQAMGPPEEVGGPLRGPGDEERLRLRWLGTRPAQLLATGRQLCTEPDRVAELAALPLPCHVVSGERDDTWPVPLLDDMALRLGARRTVIAGAEHSPNTDRPQPTARALAGFWDNLPPRPAEAEGRDAEKG
>NZ_CP010849.1|WP_044383600.1|5043920_5044988_+|hypothetical-protein
MKALMDRHRALCERAVDPLEIAAGLEAQGITDRTAAIRFRHRDVFSLAEEMYARTPRDGDARPSRRTAPPVPRARTAWVVPALLPGALCAAAVAGLRLTHGQPRLITAVAGVLAVFLATRAAVRRGPLATPGRKPTAGLPVWWLAGYALLGEGLLRTALAGGPDGPPNGTADGPWPVALAPFLALALACAPAAWTAHLFTTAARRRLTASRGLDDFAAAVRPLLLGAVALFLAALAALLAAAGAALGEPAAQPQALTLGALLLLARLLAVHGSARASSLVLSATALAQATALALLFAARLPGCGALAAPTEALVAAWGPAAVPTVTCGIGALTLLVHAARRLTKASAHARTEPAC
>NZ_CP010849.1|WP_044383602.1|5045339_5046431_+|NAD-dependent-epimerase/dehydratase-family-protein
MRVLLIGANGYIGRFVADRLLADPAVQLTALGRGDDADVRFDLATGSPGALTRFLDAVQPGVVINCAGATRGGARELTRHNTVAVATICEALRRSSCSARLVQIGCGSEYGPSQPGSSTAEDAVPRPGGPYGVSKLAATELVLGSGLDAVVLRVFSPAGPGTPAGSPLGRLAEAMRRAMQSGDGELRLGGLGVQRDFVDVRDVARAVHAASLSAAQGVINIGSGRAVRLRDVAATLARVAGYGGALHELDGPHGTPLRPAIGHPRTESLSHRAEALTHPRSELLSHLGHQGHAGPPGHPGHSVAARADADHPPAPPVAYPYPDGCGSWQQADVRTARDRLGWRPRINLEESLADIWMEAACRI
>NZ_CP010849.1|WP_044383604.1|5046418_5047216_+|phage-related-protein,-tail-component
MPYLTSAKAGTPKAGVGIGFGVPGLAHPLVAPGEWARLARPGTPLHWVVLDVAAGPGVRPDPLCREEAGRLRGAGTRVLGRLDTAYGARPLGELASEAHRYADWYRVDGFLLDRCPSGQAELDGIRHTVAAVRAIRDDAHIVLGHGIHPHPGYAESADQLVTFRGPWSDYRWSQAAEWTADHPPERFCHLVHGVPRAHLDEALLIARRQGAATVYFTDRTDGTARAGRSGGTGTTGGIEGLGDPWEAMPGYWDDIVSRIGTGVSE
>NZ_CP010849.1|WP_044383606.1|5047279_5048458_+|adenylyltransferase/sulfurtransferase-MoeZ
MSLPPLVEPAPELTVDEVRRYSRHLIIPDVGMDGQKRLKNAKVLCVGAGGLGSPALMYLAAAGVGTLGIVEFDEVDESNLQRQIIHSQSDIGRSKAESARDSVKGINPYVNVVLHEERLEADNVMDIFSQYDLIIDGTDNFATRYLVNDACVLLNKPYVWGSIYRFDGQASVFWSEHGPCYRCLYPEPPPPGMVPSCAEGGVLGVLCASIGSIQVNEAIKLLAGIGEPLVGRLMIYDALEMQYRQVKVRKDPDCAVCGENPTVTELIDYEAFCGVVSEEAQAAAADATITPKQLKEWIDEGENIEIIDVREQNEYEIVSIPGARLIPKNEFLMGTALETLPQDKKIVLHCKTGVRSAEVLAVLKNAGFSDAVHVGGGVIGWVNQIEPHKPVY
>NZ_CP010849.1|WP_044383608.1|5048667_5048976_-|hypothetical-protein
MTYLVRQVVMGAVIGVAVLVVAWVVVNRSESSAVDKDSYTAGYNAFGGAFMPTDDRSREQVEADCDSILRQRQLAAPEHGLVQKDWIQGCADAAQNKDSRFE
>NZ_CP010849.1|WP_044383610.1|5049378_5050953_-|alpha/beta-hydrolase
MARLIRWTAGVVAAALLVTGCGGGSPGHGAGGPDEGDDGSRSGRSAQRTRTPSVAPPGLPASLTSQKPDWGRCEAGADGEAPGRKWQCATLKVPLDWSKPGGETIGLALIRARARGEDRIGSLLFNFGGPGGSGLSTMPSYATTADRLRERYDLVSWDPRGVGASEGVRCRGDEEIQAAESVDATPDTPAEERRFAKDAADFGRGCQKAAGKLMAHVSTTDTARDMDLMRHVLGDAELHYFGISYGTELGGVYAHLFPKNVGRMILDAVADPTADTIGHAENQTRGFQRALDDYLESTGQDPRRGTRRIADLLRRIDGEPLPTSTPGRKLTQTLALIGIILPLYGEESRPLLTSALKAAERGDGSQLLALADGYNERDASGRYGTGSHAQRVISCLDDRQRPTLEEAKRLLPRFEKISPVFGAYLGWDTAGWCRDWPVPGQYETPEVSAPGAPPVLVVGNTGDPATPYEGARRMADELGEDVGVMLTWRGHGHVAYGKGSDCVDTAVNAYLLNGTLPKNGKVCS
>NZ_CP010849.1|WP_044383612.1|5051096_5052635_-|alpha/beta-hydrolase
MPHPSRLSAAALTATVVLSSLLAGCDDAGDEDLTRQRLDWKDCPPPSQAQGGGGVPSPLPDGGAWQCATMKAPLDWDRPDGETIGLELIRARASGPDSGRIGSLVFNFGGPGGSGVTTLPAFGQDYARLRTRYDLVSFDPRGVGRSAPVRCLDDRRLDAYFQQDTTPDDGAERAELLESTREFNAACEKNSARILPHVRTTDAARDMDLMRQVLGDRKLHYFGISYGTELGAVYAHLFPKNVGRAVFDAVVDPTQTSEQGSLGQAEGFQRALDNYAEDCTSKAEDCPVGDTPQDVKDRIARLLKDLDSRPIPGVFPRDLTQTAATSGIAQSLYSKDFWEYLTEGLERAYDGDGRVLMVLSDSLNGRSENGEYSNLAAANTAINCADDKPRYDTAYVRGRLPEFRRASALFGDFLAWGMLGCTDWPVAGAADHPDVRAPGAPPILVIGTTGDPATPYEGARRMAAALGKGVGVELTYEGEGHGAYTGESPCVREAVDRYLLDGKVPAGGTVCS
>NZ_CP010849.1|WP_044383614.1|5052732_5055471_-|membrane-protein
MKQQGEQPGDPGNTEGSSDASPRPATAGEAAGGGTAPDAGPANTTHIDEVEGDEPLLPARVHRPSDLMRLLIGVLAVAVLLGVAAFAHGTTSGLEQDITKGTGQAPDLLIKIAGLASSIAILLVPVAFAIERLIKRDGLRIADGVLAAVLAHGVTLATDLWVAKGAPGSIQDALTQPSPGDIHALTDPVHGYLAPVIAYMTAVGMSRRPRWRAVLWIVLLLDAFSMLVTGYTTPFSIILTVLIGWTVAYGTLYAVGSPNVRPTGRTLMAGLRTVGFHPVTASRVEAAPSDTAESGDRGRRYFVTLEDGPPLDVTVVDREQQAQGFFYRAWRNLTLRGFATRSSLQSLRQALEQEALLAYAAIAAGANAPKLIATSELGPDAVMLVYEHTGGRTLDSLADDEITDDLLRDTWHQVRSLQSRRIAHRRLVGDAILVDRSGTVILTDLRAGEIAAGDLLLRMDVSQLLVALGLRVGAERAVASAVSVLGPDAVADCLPMLQPIALSRSTRATLRRLARERAQRERDAVLEASRQAKQARLEAAGADAGAVSLEKPDKKAVRAEQRAEKRAIDEALEEAREEDLLTQIRHEVLRIRPQAPIEPARLERVRPRTLISFIAGAIGAYFLLTQLTHIEFGPLIANAEWGWVIAAVLFSAASYVAAAMALLGFVPERVPFLRTVAAQVAGSFVKIVAPAAVGGVALNTRFLQRAGVRPGLAVASVGASQLFGLGCHILMLLAFGYLTGTEKTPSLSPSRTVIAGLLTVAVLVLVATSVPFLRKFVVTRVRSLFAGVVPRMLDVLQRPQKLVTGIGGMLLLTACFVMCLDASIRAFGDESTSISIASVAVVFLAGNALGSAAPTPGGVGAVEATLTVGLIAVGLPKEVAAPAVLLFRLLTLWLPVLPGWLAFNHLTRKEAL
>NZ_CP010849.1|WP_044383616.1|5055657_5056044_+|DNA-binding-protein
MSEERLPDDARAEHADSLPDYAERVLEVTELIPPGRVMTYGDVAEWLGEGGPRQVGRVMALYGGAVPWWRVVRADGVLLPGHELEALDRYRAEGTPLREAGRAAEGHLPRLDLRRARWDGAACAEGHT
>NZ_CP010849.1|WP_078969274.1|5056319_5059673_+|ATP-dependent-helicase
MSSSSTTRRPPHPPVRQGSRGAYRLVRTPPARVAPPRLDAAQRAVVDHGSGPLLVLAGPGTGKTTTLVESVAARIDRGGDPERILVLTFSRKAAVELRDRMALRIGAARAPRATTFHSFGYALVRAHQGGDRPTEPLRLLSGPEQDVTVRGLLAGQADLERLGLAHVRWPDELRACLTTRGFADEVRAVLARSRELGLGPEALDAFARRIGRPDWRAAAAFLAEYLDVLDLQGVLDYAELVHRAVLLAGRPEVAERLAGQYDAVYVDEYQDTDPAQVRLLRALAGGGRTLVAFGDPDQSIYAFRGADVNGILDFPRTFPRGDGSPAPVQVLRTSRRSGATLLAATRRLAQRMPLPRLPADRVRAHREPAPVRDGGRVEVYTYPTSGAELDNIADILRRAHLEDGVPWSEMAVLVRAGSRSIPTLRRALTAAGVPLDVDGDDLPLRHEPAVAPLLTALRAVATAEAAEASRQRPGTDEPAPGTGGCWLDTETALTLLTSPLAGMDTADLRRLGRALREEERAAGDPLPPPSDELLARALAEPERLAVHDPAYARGAQRLGALLRRARERLAGGGTAEEALWDLWEGTPWPGRLERAARRGGAAGRNADRDLDAVCALFATAARAEERIGGRGALNFLEEIEAQDIAADTLTRRAVRPEAVRLMTAHRAKGLQWRLVVVAGVQEGLWPDLRRRGSLLEADRIGRDGLAEPLTPGALLAEERRLFYVAATRARERLVVTAVKAPADDGDQPSRFLTELGVEPKDVTGRPRRPLSVAALVAELRATTVDPQASDALREAAARRLARLAALADEDGRPLVPSAHPHRWWGMFEPTESKVPLRDRDKPVVLSGSALEQLAGTCALQWFLGREVKADAPATAAQGFGNVVHVLADEVASGHTPADLDVLMERLDSVWNALAFDAPWKSAQEKENARLALERFLKWHVDAHGARAGRTAVASEHDFDVTLRAGDYEVRIRGQMDRVETDGEGRAYVVDFKTGKQAPSAAEVARHPQLAVYQLAVREGAVDAVFDGARPEPGGAELVQLRLGAAKRDGGETLPKVQAQEPLDGTPGHPGEWIGELLATAAGKVLDERFTPTAGQHCTHCAFRASCSARPEGRHVVD

Crispr_ID: NZ_CP010849_18

• CRISPR_ID: NZ_CP010849_18
• CRISPR_location: 5122325-5122465
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_18

Consensus_repeat	Method
CTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGCACGGTG	CRISPRCasFinder

spacers of NZ_CP010849_18

>18.1|5122375|41|NZ_CP010849|CRISPRCasFinder
GTCGTCGACGAGGCCGCCGCGTCCAAGCTGAAGCTCGCCGG

CRISPR arrays and Neighbor proteins around NZ_CP010849_18

CRISPR arrays

The CRISPR arrays of NZ_CP010849_18

>merge|NZ_CP010849|18|5122325-5122465|CRISPRCasFinder
CTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGCACGGTGGTCGTCGACGAGGCCGCCGCGTCCAAGCTGAAGCTCGCCGGCTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGCCGGTGC

>NZ_CP010849|18|17|5122325-5122465|CRISPRCasFinder
CTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGCACGGTG	GTCGTCGACGAGGCCGCCGCGTCCAAGCTGAAGCTCGCCGG
CTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGCCGGTGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044388306.1|5118759_5119758_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP010849.1|WP_044383717.1|5119754_5120585_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP010849.1|WP_044383723.1|5123712_5124783_+|SIS-domain-containing-protein	unknown	unknown	gnl|CDD|225132
NZ_CP010849.1|WP_044383735.1|5128577_5128835_-|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP010849.1|WP_044383706.1|5113593_5114103_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP010849.1|WP_162487306.1|5125659_5126352_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP010849.1|WP_044383725.1|5124819_5125572_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187620
NZ_CP010849.1|WP_029383200.1|5116251_5117016_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP010849.1|WP_044383737.1|5129153_5130122_-|DeoR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224513
NZ_CP010849.1|WP_044383731.1|5126823_5128299_+|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl|CDD|378836
NZ_CP010849.1|WP_044383703.1|5110908_5113266_-|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|274170
NZ_CP010849.1|WP_078969281.1|5130823_5131930_-|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|274373
NZ_CP010849.1|WP_044383719.1|5120594_5122079_+|glycoside-hydrolase-family-3-protein	unknown	unknown	gnl|CDD|224389
NZ_CP010849.1|WP_044383709.1|5114185_5115814_-|sodium:solute-symporter-family-protein	unknown	unknown	gnl|CDD|271357
NZ_CP010849.1|WP_044383740.1|5130256_5130712_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044383700.1|5109850_5110909_-|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl|CDD|153108
NZ_CP010849.1|WP_078969280.1|5115810_5116068_-|DUF3311-domain-containing-protein	unknown	unknown	gnl|CDD|371707
NZ_CP010849.1|WP_044383721.1|5122613_5123399_-|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl|CDD|179028
NZ_CP010849.1|WP_044383715.1|5117412_5118672_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270450
NZ_CP010849.1|WP_004925829.1|5131947_5132361_-|anti-sigma-regulatory-factor	unknown	unknown	gnl|CDD|235217

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044388306.1|5118759_5119758_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	7.73135e-65
NZ_CP010849.1|WP_044383717.1|5119754_5120585_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.63862e-74
NZ_CP010849.1|WP_044383723.1|5123712_5124783_+|SIS-domain-containing-protein	gnl|CDD|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	7.49094e-78
NZ_CP010849.1|WP_044383735.1|5128577_5128835_-|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	8.61282e-29
NZ_CP010849.1|WP_044383706.1|5113593_5114103_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.62773e-14
NZ_CP010849.1|WP_162487306.1|5125659_5126352_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.72693e-08
NZ_CP010849.1|WP_044383725.1|5124819_5125572_-|SDR-family-oxidoreductase	gnl|CDD|187620	cd05362, THN_reductase-like_SDR_c, tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs. 1,3,6,8-tetrahydroxynaphthalene reductase (4HNR) of Magnaporthe grisea and the related 1,3,8-trihydroxynaphthalene reductase (3HNR) are typical members of the SDR family containing the canonical glycine rich NAD(P)-binding site and active site tetrad, and function in fungal melanin biosynthesis. This subgroup also includes an SDR from Norway spruce that may function to protect against both biotic and abitoic stress. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.12348e-86
NZ_CP010849.1|WP_029383200.1|5116251_5117016_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.47085e-75
NZ_CP010849.1|WP_044383737.1|5129153_5130122_-|DeoR-family-transcriptional-regulator	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	1.42069e-43
NZ_CP010849.1|WP_044383731.1|5126823_5128299_+|PAS-domain-containing-sensor-histidine-kinase	gnl|CDD|378836	pfam12282, H_kinase_N, Signal transduction histidine kinase. This domain is found in bacteria. This domain is about 150 amino acids in length. This domain is found associated with pfam07568, pfam08448, pfam02518. This domain has a single completely conserved residue P that may be functionally important. This family is mostly annotated as a histidine kinase involved in signal transduction but there is little published evidence to support this.	2.24948e-66
NZ_CP010849.1|WP_044383703.1|5110908_5113266_-|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl|CDD|274170	TIGR02506, Ribonucleoside-diphosphate_reductase_large_subunit, ribonucleoside-diphosphate reductase, alpha subunit. This model represents the alpha (large) chain of the class I ribonucleotide reductase (RNR). RNR's are responsible for the conversion of the ribose sugar of RNA into the deoxyribose sugar of DNA. This is the rate-limiting step of DNA biosynthesis. Class I RNR's generate the required radical (on tyrosine) via a "non-heme" iron cofactor which resides in the beta (small) subunit. The alpha subunit contains the catalytic and allosteric regulatory sites. The mechanism of this enzyme requires molecular oxygen. E. Coli contains two versions of this enzyme which are regulated independently (NrdAB and NrdEF, where NrdA and NrdE are the large chains). Most organisms contain only one, but the application of the gene symbols NrdA and NrdE are somewhat arbitrary. This model identifies RNR's in diverse clades of bacteria, eukaryotes as well as numerous DNA viruses and phage. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NZ_CP010849.1|WP_078969281.1|5130823_5131930_-|RNA-polymerase-sigma-factor-SigF	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	6.63164e-124
NZ_CP010849.1|WP_044383719.1|5120594_5122079_+|glycoside-hydrolase-family-3-protein	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	9.74494e-82
NZ_CP010849.1|WP_044383709.1|5114185_5115814_-|sodium:solute-symporter-family-protein	gnl|CDD|271357	cd10322, SLC5sbd, Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain. This family represents the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporter family or solute sodium symporter family) that co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. Family members include: the human glucose (SGLT1, 2, 4, 5), chiro-inositol (SGLT5), myo-inositol (SMIT), choline (CHT), iodide (NIS), multivitamin (SMVT), and monocarboxylate (SMCT) cotransporters, as well as Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) has 13 transmembrane helices (TMs): TM-1, an inverted topology repeat: TMs1-5 and TMs6-10, and TMs 11-12 (TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). One member of this family, human SGLT3, has been characterized as a glucose sensor and not a transporter. Members of this family are important in human physiology and disease.	6.32604e-63
NZ_CP010849.1|WP_044383700.1|5109850_5110909_-|ribonucleotide-diphosphate-reductase-subunit-beta	gnl|CDD|153108	cd01049, RNRR2, Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain. Ribonucleotide Reductase, R2/beta subunit (RNRR2) is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The RNR protein catalyzes the conversion of ribonucleotides to deoxyribonucleotides and is found in all eukaryotes, many prokaryotes, several viruses, and few archaea. The catalytically active form of RNR is a proposed alpha2-beta2 tetramer. The homodimeric alpha subunit (R1) contains the active site and redox active cysteines as well as the allosteric binding sites. The beta subunit (R2) contains a diiron cluster that, in its reduced state, reacts with dioxygen to form a stable tyrosyl radical and a diiron(III) cluster. This essential tyrosyl radical is proposed to generate a thiyl radical, located on a cysteine residue in the R1 active site that initiates ribonucleotide reduction. The beta subunit is composed of 10-13 helices, the 8 longest helices form an alpha-helical bundle; some have 2 addition beta strands. Yeast is unique in that it assembles both homodimers and heterodimers of RNRR2. The yeast heterodimer, Y2Y4, contains R2 (Y2) and a R2 homolog (Y4) that lacks the diiron center and is proposed to only assist in cofactor assembly, and perhaps stabilize R1 (Y1) in its active conformation.	1.45603e-110
NZ_CP010849.1|WP_078969280.1|5115810_5116068_-|DUF3311-domain-containing-protein	gnl|CDD|371707	pfam11755, DUF3311, Protein of unknown function (DUF3311). This is a family of short bacterial proteins of unknown function.	9.46246e-15
NZ_CP010849.1|WP_044383721.1|5122613_5123399_-|glucosamine-6-phosphate-deaminase	gnl|CDD|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	4.36745e-137
NZ_CP010849.1|WP_044383715.1|5117412_5118672_+|extracellular-solute-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.96487e-88
NZ_CP010849.1|WP_004925829.1|5131947_5132361_-|anti-sigma-regulatory-factor	gnl|CDD|235217	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional.	2.93233e-17

Protein sequences

>NZ_CP010849.1|WP_044383719.1|5120594_5122079_+|glycoside-hydrolase-family-3-protein
MTTFASGTDTLTRDALTVLQPGFTGTTAPDWLLRRLGEGLATVGLFGRNITTPEQLAALTAQLRAERDDVLVAIDEEGGDVTRLEVRTGSSFPGNHALGAVDDVELTREVAAELGRRLAACGVNFNWAPSADVNSNPGNPVIGVRSFGADPALVARHTAAYVTGLQSAGVAACTKHFPGHGDTAVDSHLDLPRIDADPEVLAERELVPFRAAIAAGTRAVMSAHILVPALDPDHPATLSRRILTDLLRGELGYDGLIVTDGMEMRAISATYGIERGSVLALAAGADAICVGGGLADEETVRRLRDALVAAVRSGDLAEERLADAAQRIRTLARTTADPLPAAAGAGDEAVGLRAARRALKATGADGFTPLTEAPYVAALTPVANIAVGDDTPWGVAAELARLLPGTETGGFTGADAGRGVLEAAGHRRIVAVVRDEHRHPWMAAALDTLLAARPDTVVVEMGVPQATPRGALHLATHGAARVCGRAAAEVIAGI
>NZ_CP010849.1|WP_044383717.1|5119754_5120585_+|carbohydrate-ABC-transporter-permease
MKRSLFGRLWPNLTAAVLFVGFVFPVYWMFATAFKPTGDIITEDPVWFPTDITFEHFKTATGVDHFWTYVTNSLIVTVLAVVFSLIIALAGSFALARMRFRGRRGFIIGFMLAQMAPWEVMVIAMYLIVRDASMLNSLVPLTVFYMMMILPFTILTLRGFVAAVPKELEEAAMVDGCTRVTAFRRVILPLLAPGLMSTSLFGFVTAWNEYALVLVLNKDAEAKTLPLWLSGFQTAFGDDWGATMAASSLFAVPILILFVFLQRRAVNGLTAGAVKG
>NZ_CP010849.1|WP_044388306.1|5118759_5119758_+|sugar-ABC-transporter-permease
MTVQTERPPSGPAEGPPDVRKPGGAGPGRTTPRAASRAGALAPYLLLLPACAATVLLLGWPLLKDVLLSFQNLNMAQLIQHVTEWNGFDNYREVLTGEDFWRVTLRSILFTAVNVALVMVLGGLIGLLLARLGKRMRLTLLIGLVLAWAMPVVAATTVYQWLFAQRFGVVNWVLDRLGWHSMADYSWTSSQMSTFFVVTVLIVWQSIPFVAINLYAATTTIPGELYEAAALDGASAWRSFTTVTMPFLRPFLYATTFLEIIWVFKAFVQVFTINGGGPDRLTEILPVYAYVEGVGNQHYGMGAAIAVLTILILLGLTAYYLRIVLKQEEDEA
>NZ_CP010849.1|WP_044383715.1|5117412_5118672_+|extracellular-solute-binding-protein
MKRKLTAAIGIAGMIFSIAACGGGDGGSESEGPQTLTVWMMDGSTPDQWQKDLAAEFEAKTKAKVKFETQTWNGIQQKLTTALSEENPPDVFEIGNTQTPAYAKTGGLADLSGLKSEIGADWTASLNKSAVYEGKQYAAPWFVVNRVVIYNKKVWADAGIKTPPKTRDEFHAALKKIGEKTDAEPIYLPGQNWYHFVGLVIGEGGELVKKDGDKYVSNLADPKVVAAAETYKKFQALSKAPKDKDEATPQQGEIFAKGNVGAIIGMGWEAGTAIKANPAIEKEIGYFTIPGETAAKPEGVFLGGSNLAVAAGSKKQDLAKEFLKIALSDKYEGRLAKLNGVIPNKEALQTNLEGNPAAEAAAPAVAGGDTTPLIPEWAAVENDPNPIKTYLTAVLNGKSPAEAARQVEGEFNKRLAQQQ
>NZ_CP010849.1|WP_029383200.1|5116251_5117016_-|GntR-family-transcriptional-regulator
MSTDVSSAENENGTGVRTARVPKYYRLKRHLLDMTRTLPPGTPVPPERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRAQGLEPTSQLLDIGYITADDRLAGLLDIAAGGRVLRIERLRMANGEPMAIETTHLSAKRFPALRRSLAKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRHSLDRDGQPVEWVRSVYRGDRYKFVARLKRPQD
>NZ_CP010849.1|WP_078969280.1|5115810_5116068_-|DUF3311-domain-containing-protein
MSQPPEVNRGPVVTPVRVVIALCLVAPFVAMLWVDSYAKVEPEFIGIPFFYWYQMAWVVVSTALTMIAYKLWQRDQRSRRGGAGR
>NZ_CP010849.1|WP_044383709.1|5114185_5115814_-|sodium:solute-symporter-family-protein
MKDGVNGVALAVFIFFFLLVTVMGFLAARWRKAENEHSLDEWGLGGRSFGTWITWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLWSVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGGEDTNWFIKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDALIYIVIAVAIIYIPIKLGGFDDIFAKAGDAFAQTNPATGQPRGALAPGEAGQWTYATLALGSALALFMYPHSITATLSSRSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGIKVSNGQLAIPQLFEDMFPDWFAGVAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATAEQETKVSKLVSLLVKVGALAFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTLAAYGVASPTQKHFGGSAKEIPGIGEIGYIGLTAFVLNLVVTVVLTVVLRAVKAPDGVDETSPEDYTADAGDPGVQTELPPATAGAAH
>NZ_CP010849.1|WP_044383706.1|5113593_5114103_-|GNAT-family-N-acetyltransferase
MDIVIRRAVPGDYAPLGEITAHAYLQDGLLDFGESDAYLGELRDVAGRAAAAEVLAAVEDERVVGGVTFVPSGGPMADIARPGEAEIRMLAVAHAARGRGVGEALVRACVERARAVEGCVRVVLSTQRAMRTAHRLYERLGFVRTPERDWNPLPELDDITLLTYALTLR
>NZ_CP010849.1|WP_044383703.1|5110908_5113266_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MTIAPADPASAIQPEHDGPGAALLRTLTELTADLPDADPGRVAAAALRGRSARADETELRELATEAAAGLIAEDPAYSKLAARLLTIGIRAEAASQGVTAFTESVATGHREGLIADRTAAFVRRHAERLDALADPHADDRFGYFGLRTLYSRYLLRHPITRKVIETPQHFLLRVAAGLAEDDTTRALDEVAALYGLMSRLDYLPSSPTLFNSGTRHPQMSSCYLLDSPKDELDSLYERYHQVARLSKHAGGIGIAYSRVRSRGSLIRGTNGHSNGIVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHADIEEFLELRDNTGEDARRTHNLNLAHWVPDEFMRRVAADEPWSLFSPSDVPELVDLWGEEFDAAYRAAEAKGLARKRLPARELYGRMMRTLAQTGNGWMTFKDAANRTANQTAEPGHVIHSSNLCTEILEVTDDGETAVCNLGSVNLGAFVDPAARDIDWERLDAAVRTAVTFLDRVVDINFYPTGQAARSNARWRPVGLGAMGLQDVFFKLRLPFDSAEAKGLSTRIAERIMLAAYEASADLAERNGPLPAWEKTRTARGVLHPDHYDTEPAWPERWAALRERLAAVGLRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRETLSGEFLQVNSYLVDDLKRLGVWDARTREALREASGSVQGLTWIPEDVRRLYRTAWEIPQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIARAARATVPVPAAADPEAVACSLENPESCEACQ
>NZ_CP010849.1|WP_044383700.1|5109850_5110909_-|ribonucleotide-diphosphate-reductase-subunit-beta
MTSTPAATTPGAATTGAGRTQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLHSDVADLAKLTPGEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAVHVQFYLTLLDTYLPDPEDRAAAFAAVENIPSIREKAEFCFRWMDSVEQIDRLESKADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDVVDTVRKEEPDLFDDGLRQQVTDMLREAVEAELQFARDLCGDGLPGMNTDSMRQYLECVADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVAGTVDLDEDF
>NZ_CP010849.1|WP_044383721.1|5122613_5123399_-|glucosamine-6-phosphate-deaminase
MEVVIVPDARAGGELIAEAMAKLLRRKPDALLGVATGSTPLPVYEALAARVRSGAVDTSRARIAQLDEYVGLPAEHPESYRSVLRREVLEPLGIGMDAFMGPDGTAEDVQGACEAYDRALAEAGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRVDNARFFDGDIGQVPHHVITQGIGTILEARHLVLLATGEGKADAVAASVEGPVAAVCPASALQLHPHATVVVDEAAASKLKLAGYFRHAYANKPAWQGI
>NZ_CP010849.1|WP_044383723.1|5123712_5124783_+|SIS-domain-containing-protein
MTATAPDDHRELPGRIMAREMAEQPAVLRRILAEGAPTIRQVAERIAARAPRFVLLTARGTSDNAALYAKYLLEIRLGLPCGLTSMSTVTAYGARPDLTDVLAVTVSQSGGSPDLVASTRAAREAGAITLAVTNNPDSPLAGVSEYHIDIMAGPEKALPATKTYTASLLALYLFTEGLRGGDGAPAQMLPGLAEQLLARHDEVRALAARYRFAERMVITSRGYGYPTAKEAALKLMETSYIPALSYSGADLLHGPLAMVDNVSPVIAVVTDGRGGEALQPVLDRLRGRGADLMVVGPGRYVEKASAGFVLPTEGVPEEIQTVLEIIPLQLLAYEVTIARGQDPDAPRALAKVTETH
>NZ_CP010849.1|WP_044383725.1|5124819_5125572_-|SDR-family-oxidoreductase
MGVLTGRTALVTGASRGIGRGIAERLGRDGARVAVHYGRNETAAKETVAAIEAAGGSAFAIGVELGVPGDAEALWEEFDRHADGLDILVNNAGIGSARPIGEITEDDFDRVFAVNVKAPFFLLKHGMTRLRDGGRVVNISSGLARTAVMPDNVAYAMTKGALDVFSRDLSKVLGARGITVNSVAPGIIDTDNTAELLHGSPDGWARAAAYSALGGVGTPADVADVVAFLVSDGGRWVTGSWVDATGGSLT
>NZ_CP010849.1|WP_162487306.1|5125659_5126352_+|TetR-family-transcriptional-regulator
MHPMVSGEEREGGRTAARTEAGAEPAAGAGARRASRPRGRPRSFDRATALEKALMAFWERGYEATSVSDLTGVMEIGAPSLYAAFGDKRSLFEEAVRVYGERYGAFGERALAEEPTARAAVERTLREAAAEYTAPGRPHGCMVIHAAANCSTPEVEESLRRRRNANIAAFERRIRADVDAGLLPPDTDAAALARHTGAMIQGMSQQARDGATREELQALAEIAMTVWPRS
>NZ_CP010849.1|WP_044383731.1|5126823_5128299_+|PAS-domain-containing-sensor-histidine-kinase
MPSMNELVRQHTALDDSDLEWLHLLVSEWQLLSDLSFADLVLWVPTRDGTRYVSVAQMRPNTGPTSYQDDMVGHLVPRGRRPMLDVALDEGRIVREGDPEWREEVPVRVESIPVRRQGRVLGVIARNTNLLTVRTPSRLELTYLQSASDLAQMIAAGAFPFENQQVDMDASPRVGDGLIRLDADGIVQYASPNALSAYHRLGLAADLVGHHLGRTTAELAPSRGPVDEALAKVASGWAPREFEIEAHDGVIQFRAIPLKPKGTRIGSLVLLRDVTELRRRERELITKDATIREIHHRVKNNLQTVAALLRLQARRIGSDRGREALEEAVRRVGSIAIVHETLSQNLDERVEFDDIADRVLAMVAEISPGKVTGRRTGRFGILDAEVATPLSMVLTEILQNALEHGFREGDTGTVEVAAVRGGTTKEARLLVTVQDDGVGLPEDFDPHRSGNLGLQIVRTLVEGELGGTFDMVPAPGHGTRVILDIPVRAQK
>NZ_CP010849.1|WP_044383735.1|5128577_5128835_-|WhiB-family-transcriptional-regulator
MDWRHRAVCREEDPELFFPIGSTGPALLQIEEAKAVCRRCPVIEQCLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA
>NZ_CP010849.1|WP_044383737.1|5129153_5130122_-|DeoR-family-transcriptional-regulator
MRALLVVNPAATTTSARTRDVLIRALASEMKLEAVTTEYRGHARDLGRQAAQSDDIDLVVALGGDGTVNEVVNGLLHAGPDPEHLPGLAVVPGGSTNVFARALGLPNHAVEATGALLDALREGSERTVGLGLTSGTPGSEDEAVPARWFTFNAGLGFDAGVVGRVEQHRERGKKSTHALYVRQVLRQLVGEPHRRSGTISLERAGEEPVTDLVLSIVSNTSPWTFLGNRPIYASPKATFDTGLDVFGLSRLSTAAVARYGTQLLTSSPERGPHGRHAVSLHDLTEFTLQSKVPLPLQMDGDHLGLRTSVTFTGVRRALRVIV
>NZ_CP010849.1|WP_044383740.1|5130256_5130712_+|hypothetical-protein
MSSEQTPAPEAAESTAAPGARPGRLTVAAGLNALEGLALVVGGVWMLVGGLTGHPDDRTSAVTGGVTLIVLSLLPLLAARGLLALRGWSRGPAVITQIMALPVAYNLLQADSIAIPAGIALAVVAVAALVLIVNPETTRALGIRGPGNAQE
>NZ_CP010849.1|WP_078969281.1|5130823_5131930_-|RNA-polymerase-sigma-factor-SigF
MRDEERGTRELPAEGTRSPNGAPRTANGIDGIPEQARPHPEDAPTGAGLPADGQRPGDEDGAVRSAPADGRIGGTPVRPVRARARARERATGGTMSEHERHSEDEAPAARGAQGTHDPQDRSGARALFAELRTLGKDSPEYAELRNRLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLSLTTATAELSQLHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE
>NZ_CP010849.1|WP_004925829.1|5131947_5132361_-|anti-sigma-regulatory-factor
MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDEIEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTVLSALAGKVSSAVDEDKTVSISLYKQRGAGPGPA

Crispr_ID: NZ_CP010849_19

• CRISPR_ID: NZ_CP010849_19
• CRISPR_location: 5349338-5349474
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_19

Consensus_repeat	Method
CTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACG	CRISPRCasFinder

spacers of NZ_CP010849_19

>19.1|5349381|51|NZ_CP010849|CRISPRCasFinder
GTGGTGAAGGTGACGCGCGCGAGGGCGGCGTCGCGGTCGGCGGCGGTGATC

CRISPR arrays and Neighbor proteins around NZ_CP010849_19

CRISPR arrays

The CRISPR arrays of NZ_CP010849_19

>merge|NZ_CP010849|19|5349338-5349474|CRISPRCasFinder
CTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGGTGGTGAAGGTGACGCGCGCGAGGGCGGCGTCGCGGTCGGCGGCGGTGATCCTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACG

>NZ_CP010849|19|18|5349338-5349474|CRISPRCasFinder
CTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACG	GTGGTGAAGGTGACGCGCGCGAGGGCGGCGTCGCGGTCGGCGGCGGTGATC
CTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_078648142.1|5352894_5353443_+|F0F1-ATP-synthase-subunit-B	unknown	unknown	gnl|CDD|180240
NZ_CP010849.1|WP_044383953.1|5353439_5354255_+|F0F1-ATP-synthase-subunit-delta	unknown	unknown	gnl|CDD|237387
NZ_CP010849.1|WP_044383948.1|5347816_5349163_+|crotonyl-CoA-carboxylase/reductase	unknown	unknown	gnl|CDD|188164
NZ_CP010849.1|WP_044383940.1|5289506_5301338_+|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NZ_CP010849.1|WP_052808665.1|5347273_5347774_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_107071056.1|5335788_5340423_-|acyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|225858
NZ_CP010849.1|WP_107071219.1|5340422_5341268_-|polyketide-synthase	unknown	unknown	gnl|CDD|238429
NZ_CP010849.1|WP_029382920.1|5351727_5352522_+|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl|CDD|235617
NZ_CP010849.1|WP_078969289.1|5322201_5326773_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187659
NZ_CP010849.1|WP_029382919.1|5352591_5352840_+|ATP-synthase-subunit-C	unknown	unknown	gnl|CDD|169138
NZ_CP010849.1|WP_159392916.1|5335262_5335466_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044383944.1|5326911_5328126_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP010849.1|WP_029382913.1|5358497_5358872_+|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl|CDD|184055
NZ_CP010849.1|WP_078969291.1|5349809_5350754_+|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|181133
NZ_CP010849.1|WP_029382916.1|5354391_5355999_+|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl|CDD|236448
NZ_CP010849.1|WP_044383956.1|5356937_5358386_+|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl|CDD|236447
NZ_CP010849.1|WP_029382915.1|5356020_5356938_+|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl|CDD|235535
NZ_CP010849.1|WP_078969290.1|5334374_5335307_-|KR-domain-containing-protein	unknown	unknown	gnl|CDD|187659
NZ_CP010849.1|WP_044383942.1|5301611_5315576_+|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NZ_CP010849.1|WP_029382921.1|5351076_5351490_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_078648142.1|5352894_5353443_+|F0F1-ATP-synthase-subunit-B	gnl|CDD|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	2.60723e-39
NZ_CP010849.1|WP_044383953.1|5353439_5354255_+|F0F1-ATP-synthase-subunit-delta	gnl|CDD|237387	PRK13430, PRK13430, F0F1 ATP synthase subunit delta; Provisional.	7.45844e-111
NZ_CP010849.1|WP_044383944.1|5326911_5328126_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	6.31214e-100
NZ_CP010849.1|WP_044383940.1|5289506_5301338_+|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP010849.1|WP_107071056.1|5335788_5340423_-|acyltransferase-domain-containing-protein	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP010849.1|WP_107071219.1|5340422_5341268_-|polyketide-synthase	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	8.27824e-134
NZ_CP010849.1|WP_029382920.1|5351727_5352522_+|F0F1-ATP-synthase-subunit-A	gnl|CDD|235617	PRK05815, PRK05815, F0F1 ATP synthase subunit A; Validated.	1.59406e-52
NZ_CP010849.1|WP_078969289.1|5322201_5326773_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187659	cd08956, KR_3_FAS_SDR_x, beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 3, complex (x). Ketoreductase, a module of the multidomain polyketide synthase (PKS), has 2 subdomains, each corresponding to a SDR family monomer. The C-terminal subdomain catalyzes the NADPH-dependent reduction of the beta-carbonyl of a polyketide to a hydroxyl group, a step in the biosynthesis of polyketides, such as erythromycin. The N-terminal subdomain, an interdomain linker, is a truncated Rossmann fold which acts to stabilizes the catalytic subdomain. Unlike typical SDRs, the isolated domain does not oligomerize but is composed of 2 subdomains, each resembling an SDR monomer. The active site resembles that of typical SDRs, except that the usual positions of the catalytic Asn and Tyr are swapped, so that the canonical YXXXK motif changes to YXXXN. Modular PKSs are multifunctional structures in which the makeup recapitulates that found in (and may have evolved from) FAS. In some instances, such as porcine FAS, an enoyl reductase (ER) module is inserted between the sub-domains. Fatty acid synthesis occurs via the stepwise elongation of a chain (which is attached to acyl carrier protein, ACP) with 2-carbon units. Eukaryotic systems consists of large, multifunctional synthases (type I) while bacterial, type II systems, use single function proteins. Fungal fatty acid synthesis uses a dodecamer of 6 alpha and 6 beta subunits. In mammalian type FAS cycles, ketoacyl synthase forms acetoacetyl-ACP which is reduced by the NADP-dependent beta-KR, forming beta-hydroxyacyl-ACP, which is in turn dehydrated by dehydratase to a beta-enoyl intermediate, which is reduced by NADP-dependent beta- ER. Polyketide synthesis also proceeds via the addition of 2-carbon units as in fatty acid synthesis. The complex SDR NADP-binding motif, GGXGXXG, is often present, but is not strictly conserved in each instance of the module. This subfamily includes KR domains found in many multidomain PKSs, including six of seven Sorangium cellulosum PKSs (encoded by spiDEFGHIJ) which participate in the synthesis of the polyketide scaffold of the cytotoxic spiroketal polyketide spirangien. These seven PKSs have either a single PKS module (SpiF), two PKR modules (SpiD,-E,-I,-J), or three PKS modules (SpiG,-H). This subfamily includes the second KR domains of SpiE,-G, I, and -J, both KR domains of SpiD, and the third KR domain of SpiH. The single KR domain of SpiF, the first and second KR domains of SpiH, the first KR domains of SpiE,-G,- I, and -J, and the third KR domain of SpiG, belong to a different KR_FAS_SDR subfamily. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type KRs have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.27666e-163
NZ_CP010849.1|WP_029382919.1|5352591_5352840_+|ATP-synthase-subunit-C	gnl|CDD|169138	PRK07874, PRK07874, ATP synthase F0 subunit C.	3.88938e-17
NZ_CP010849.1|WP_044383942.1|5301611_5315576_+|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP010849.1|WP_029382913.1|5358497_5358872_+|F0F1-ATP-synthase-subunit-epsilon	gnl|CDD|184055	PRK13442, atpC, F0F1 ATP synthase subunit epsilon; Provisional.	3.44328e-38
NZ_CP010849.1|WP_078969291.1|5349809_5350754_+|3-hydroxybutyryl-CoA-dehydrogenase	gnl|CDD|181133	PRK07819, PRK07819, 3-hydroxybutyryl-CoA dehydrogenase; Validated.	1.08514e-164
NZ_CP010849.1|WP_029382916.1|5354391_5355999_+|F0F1-ATP-synthase-subunit-alpha	gnl|CDD|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0
NZ_CP010849.1|WP_029382915.1|5356020_5356938_+|F0F1-ATP-synthase-subunit-gamma	gnl|CDD|235535	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated.	4.73207e-134
NZ_CP010849.1|WP_078969290.1|5334374_5335307_-|KR-domain-containing-protein	gnl|CDD|187659	cd08956, KR_3_FAS_SDR_x, beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 3, complex (x). Ketoreductase, a module of the multidomain polyketide synthase (PKS), has 2 subdomains, each corresponding to a SDR family monomer. The C-terminal subdomain catalyzes the NADPH-dependent reduction of the beta-carbonyl of a polyketide to a hydroxyl group, a step in the biosynthesis of polyketides, such as erythromycin. The N-terminal subdomain, an interdomain linker, is a truncated Rossmann fold which acts to stabilizes the catalytic subdomain. Unlike typical SDRs, the isolated domain does not oligomerize but is composed of 2 subdomains, each resembling an SDR monomer. The active site resembles that of typical SDRs, except that the usual positions of the catalytic Asn and Tyr are swapped, so that the canonical YXXXK motif changes to YXXXN. Modular PKSs are multifunctional structures in which the makeup recapitulates that found in (and may have evolved from) FAS. In some instances, such as porcine FAS, an enoyl reductase (ER) module is inserted between the sub-domains. Fatty acid synthesis occurs via the stepwise elongation of a chain (which is attached to acyl carrier protein, ACP) with 2-carbon units. Eukaryotic systems consists of large, multifunctional synthases (type I) while bacterial, type II systems, use single function proteins. Fungal fatty acid synthesis uses a dodecamer of 6 alpha and 6 beta subunits. In mammalian type FAS cycles, ketoacyl synthase forms acetoacetyl-ACP which is reduced by the NADP-dependent beta-KR, forming beta-hydroxyacyl-ACP, which is in turn dehydrated by dehydratase to a beta-enoyl intermediate, which is reduced by NADP-dependent beta- ER. Polyketide synthesis also proceeds via the addition of 2-carbon units as in fatty acid synthesis. The complex SDR NADP-binding motif, GGXGXXG, is often present, but is not strictly conserved in each instance of the module. This subfamily includes KR domains found in many multidomain PKSs, including six of seven Sorangium cellulosum PKSs (encoded by spiDEFGHIJ) which participate in the synthesis of the polyketide scaffold of the cytotoxic spiroketal polyketide spirangien. These seven PKSs have either a single PKS module (SpiF), two PKR modules (SpiD,-E,-I,-J), or three PKS modules (SpiG,-H). This subfamily includes the second KR domains of SpiE,-G, I, and -J, both KR domains of SpiD, and the third KR domain of SpiH. The single KR domain of SpiF, the first and second KR domains of SpiH, the first KR domains of SpiE,-G,- I, and -J, and the third KR domain of SpiG, belong to a different KR_FAS_SDR subfamily. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type KRs have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	6.71278e-32
NZ_CP010849.1|WP_044383956.1|5356937_5358386_+|F0F1-ATP-synthase-subunit-beta	gnl|CDD|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NZ_CP010849.1|WP_044383948.1|5347816_5349163_+|crotonyl-CoA-carboxylase/reductase	gnl|CDD|188164	TIGR01751, crotonyl_CoA_reductase, crotonyl-CoA carboxylase/reductase. The enzyme represented by this model can convert crotonyl-CoA to butyryl-CoA (crotonyl-CoA reductase activity), but more importantly, in the presence of CO2, generates (2S)-ethylmalonyl-CoA. In serine cycle methylotrophic bacteria this enzyme is involved in the process of acetyl-CoA to glyoxylate. In other bacteria the enzyme is used to produce extender units for incorporation into polyketides such as tylosin from Streptomyces fradiae and coronatine from Pseudomonas syringae.	0

Protein sequences

>NZ_CP010849.1|WP_044383948.1|5347816_5349163_+|crotonyl-CoA-carboxylase/reductase
MSLLSEAVVAGAPPEELERLPLPDEYTAAYLRAEDAEMFRGVADKDVRKSLRVGPVAMPEPAPDEVLVAVMASAVNYNTVWSAIFEPIPTFRFLRQFAAQGGWAARHDLPYHQVGSDGAGVVVRTGSAVRHWKTGDHVVVSCVQADDQEAATQADGMLGAEQRIWGFETNFGGLAHYALVRASQLIPKPAHLSWEEAACNPLCAGTAYRMLVGDRGARLKQGDVVLIWGAAGGLGAYAVQLVKNGGGIPVGVVSSPAKAEAARRLGCEVVIDRQEIGLDDRTGDDPRAVIETGKRLGRLIRERVGEDPHIVFEHVGRATFGVSVFVVRRGGTVVTCGSSTGYHHTYDNRYLWMKLKRIIGSHAANLQEQWELNRLLSLGHIVPTLSAVYPLAEIGEAARSVQENRHIGKVGVLCLATAPGQGVTDPALRARVGESRLNVLRELPDPRP
>NZ_CP010849.1|WP_052808665.1|5347273_5347774_+|hypothetical-protein
MSAPEVDTAAPEKPEFSKPSAPEKMRDLDFLLGDFRAEWTNLLADPADTGIAEWNTTATFSGHAYEMTQYVAQHDVNGRFVFQWDGVNEKFTGYYYDDWGNRATVECAGWEDGHLAFVGECFGFGKSFRLKERFEIVDENHYVKRGFVQLDGADWMPADEIHCYRV
>NZ_CP010849.1|WP_107071219.1|5340422_5341268_-|polyketide-synthase
MACRYPGGVATPEELWELVAGGRDAIAAMPGDRGWDVESLYDPEMSRPGTSCVREGGFLYDAADFDPEFFGISPREALAMDPQQRLLLETSWEALESAGVDPRSVRGSRTGVFTGVMYHDYASDQGTLPEEVQGLIGIGSAASVASGRVAFTLGLEGPAITIDTACSSSLVALHLAVQALRGGECDLALAGGVTVMSSPGVFVELSRQGGLSPDGRCKSFSDDADGTGWGEGAGLLLVERLSDARRNGHPVLAIVRGTAVNQDGASNGLTAPNGPSSYNFV
>NZ_CP010849.1|WP_107071056.1|5335788_5340423_-|acyltransferase-domain-containing-protein
MYAIRSYYVSDARRNGHPVLAIVRGTAVNQDGASNGLTAPNGPSQQRVIEQALANARLGTADVDAVEAHGTGTRLGDPIEAQALLATYGQGRDAERPLWLGSVKSNIGHTQAAAGAAGIIKMVMAMRHGRIPGTLHVGTPSTEVDWDAGAVRLLTEAQEWPAAGRPRRAAVSSFGISGTNAHVILEQPPAQAPSDTPAAPSAPAPFGAVPWVLSGHTPEALRAQAGKVAAHLAGRPEASAADVALSLAGRTRLPHRAVVLGADRAALLAGASALGAHDPRAAGALPPGIVEGTAAGDGRVVFVFPGQGAQWAGMAVDLLDGAPVFRDRLRECEETLRPHTGWSLTAVLRGEPGTPPWDRVDVVQPALWAVMVSLAALWRSYGVEPAAVIGHSQGEIAAACVSGALDLADGARVVALRARAIGARLAGKGGMVAVPLSAPAARELIGGWGERISVASVNGPATTVVAGEADALGELLAHCEERGVRARRIPVDYASHTAQVAEIESELAAELAGLSPRSSAIPFFSTLTGAALDTARLDGSYWYENLRHPVEFERAVGAALEQGFSLFAEMSPHPVLVPSVQDCAEAAGRSAGAVGSLRRDDGGPLRFLTSVAELHTLGAEVDWSPALASTGARPVPLPTYAFQRRRFWLQGSRDAGDVAAAGLDAAGHPLLGAAVSLAGGDGVLLTGRLSGRTRPWLLDHAVGGTVLLPGTAFVELAIRAGDHLGHPHLEELTLQAPLVLGPREEVTVQVRAVPEQSADGRCAVTVHSRAEGGEWTLHALGTLSRHTPAQPAAQAAWPPPGAEPVAVDGVYDLLAEGGYHYGPAFRGLRAVWRRGEELFAEIALPDEERAEAGRFGVHPALLDAALHAMAFAEGPQAGVRLPFAWTGVHLYASGAVSARVRLTRAQDRIGILLSDDTGRPLAAVESLVTRPADLPAAGAGAPEDAQFHLEWTPLPEPEAVPDWVLVGDDPFGLAGSAPRVAAGLDELGEVPATVVVCLAPQPPADPVAAAHDAAQETLERVRAWLAEDRFAAARLVFVTRGAVAAGDDEDVSDLPHAAGWGLVTSAYSEHPGRFGLVDLDGHEESREVFARALGHAEPRLAVRAGAVRAPRLSRTASHPALVPPGSGPWRLVSTGRGTIENLSLVPCPEVLDPLPPGRVRLAVHAVGLNFRDVIVALDMVAGQAGIGGDVAGTVLEVGAGVTNVAVGDRVLGLCPESFGPVAVTDHRFLTRMPDDWSFEQAAAVPITHTTAYYGLVDLAGVRPGESVLVHAAAGGVGIAAVQLARHLGAEVYGTASPGKWDTLRRHGLDDAHIASSRTLEFEEAFTRTSGGRGMDVVLDCLANEFVDAGLRLLPRGGRFLEMGKTDKRDPAQVAAACPGVAYQAYDIMEAGPDRIQEMLLAIMELYRDGALVPPPITTYDVRRAREALRDLSQAKLVGKAVLRVPQGIDREGTALITGGTGTLGAHLARHLVHHHGVTHLLLTSRQGPTAPGARELAAELTTAGAHVTLTACDTSDPRQLAHLLTTIPPDHPLTTVIHTAGTLV
>NZ_CP010849.1|WP_159392916.1|5335262_5335466_+|hypothetical-protein
MSGGAEFVITSYSIHYTKLYEWAPRVPVPPVISAVLSRSMPCGTRSTALPTSFAWLRSRSASRARLV
>NZ_CP010849.1|WP_078969290.1|5334374_5335307_-|KR-domain-containing-protein
MYAIRSYYELGTPGQANYAAANTYLDALAHHRRAHGQPATSLAWGLWSERSAMTAHVGDAEVERMGRAGAGALETAEGLALFDRACRTDVPLQVLSRIDTAALRAAPEQVAPLLRGLVRGASRRTAGPGGQGPDLGAQLAALPPVERQRRLLDLVRSHAATVLGHTSAAAIAPERAFKELGFDSLTAVEFRNRLGAATGLRLPATLVFEHPTPAALTELLLAELAPAGVSGVEAALAGLEGLGAALAAIGPDEAGRDRVTRRLRALLSQWGEAAVSPGAGAADPAPADDDLDAASTDDLFAAIDQGFGLT
>NZ_CP010849.1|WP_044383944.1|5326911_5328126_-|cytochrome-P450
MSDATTEPIAFPFPDPPSVCDLPPELAEVRDGRSVAEVRFPDGITGYLVTKHADVRKVLVDSRFSSKVMASAAAAMSETETGKLMNESLVGMDAPEHTRLRKLVSRGFTARRVESLRPRVRELVAELLDEMETKPRPVDLVKNFSLPLPVRVVCELLGVPAEDQDTFHAWSNALLGDWQQVVEKEAATVALVKYFGELLEAKRKAPADDLMSALIAAREDDDTLTEREIIALCIGILSAGHETTANQISMFLVQLLRHPEQFAALKADPAALPQAVDELLRYVPLTTTGGIIPRLTTAEVELGNGEVLPAGAVVLPAVATANRDPEVFEDGERLDLTRAVNPHLAFGAGIHYCLGAQLARIELQEALGALLERMPQVRLAVPESELRLKPASIIRGLESLPITW
>NZ_CP010849.1|WP_078969289.1|5322201_5326773_+|SDR-family-NAD(P)-dependent-oxidoreductase
MGRELCESFPVFAAAFDEVCGRLDGLLERPVKDVVFGDGEALGWTVFAQAGLFAVEVALFELLVSWGVRPDVVVGHSIGGLAAAYVAGVWSLDDACRIVAARGRLMQALPAGGAMVAVQVAEEDLGELPEGVSVAAVNGPRSLVLSGDEEPVVGLAGRLAERGCRTKRLAVSHAFHSARMEPMLGEFRKVLEQAEFRAPRLVLVSDVSGVVAGEEVLSPEYWVRHVRGTVRFADAVGCVLSRGVDKVLEVGPGGALVAMAEEVVDGAGTASVVCVPALRGGRGEAESLTRAVGRLHAHGTGVDWAAYWAGRGARRIDLPTYPFQHQRYWISSGGAAAGDPASIGLTAAAHPLLRAAVTVPDTDGALFTGRLSLTEQPWIADHAMLGTALLPGTAFVELALHAGGQLGCDTIDELTLEAPLILREHESRAVQVMVGGPDDTGRRPISLHSRSLAADGRTGDDPDGRPWTRHATGLLAPAGTTEPAGSATAPWPPAGADTYPVEDFYDNLATAGFTYGPVFQGLRALWRKDGDLFAEVCLPEAAGDDTGFTAHPALLDAALQPLALGILGHAPGRDAVPSGMPFAWNGVRLHATDAPVLRVHLAPAGRSEVSVLVTDDEGLPVASIGSLTLREPVLEQFAPAEAEAGQAAREREESGPLHTLTWTPLTTDARTAGGEWAMLGFDPLEIRPRFVAAGLVGTPYLDPQSLIDTVASGAPAPQVVAMSCHGGDQGGILAAGHDLAHRVLETLQHWLSAAPLAGSRLLLLTRGAVSASDGDPVQDIAAAPVWGLVRAAQSEHPGRIVLIDMDDDDASYRALPAVLATGEPQVMLRAGAATVPRLARHTDEPRGGAGFGPEGTVLVTGGTGALGAVVARHLVAEHGVRHLVLAGRRGAAAPGARELLAELREAGADVRAEACDVADREQLAALLARIPAEQPLSGVVHTAGVLDDGTVEALTPARFDEVLRAKADAAWHLHELTREAGLREFVLFSSAAGLLGSRGQANYAAANAFLDTLAAHRRDQGLPATSLAWGWWDQPGGMGAGLGRVERARMAGAGVSAFTAESGMAAFDAALAVRDRSLLVPIRLNTAVPAAGAEQVPPLLRELIRAPRRRPRRSGRRTATHLRDRLATLTPDELLAELTALVRTEVAQVLGHSDGDAIEEDRSFGEMGFDSLTSVELRNRLGDATGLRLASTAVFDHPTPAELARALAEQLPAAGAPGAPAPAAPAARAEQDGEEVGQAAVLGGVEALYRRAIQMGRIDISHAVLRMSVDLRETFSDPAEVRGGPEPVRLGAGDRHPMIIGFPSQSVWASNQELVSLAGPLKGLRDVWSLMLPGFVTGQPVADSVDTAVEYAVQRILALTDGRPFVLAGRSSGGRPAHEVTTRLERLGRPPQGLVLIDSYLAGYDATSYIVPVMERKALELEKDFGRITGTRLTAMQSYFGLFEFWEPQEITTPTLLVRATECYGVEPGEPQPPAEQWQASWPMPHDTVDVPGNHYTMLEGNGEVTAARIHEWLLKQEPQQRS
>NZ_CP010849.1|WP_044383942.1|5301611_5315576_+|type-I-polyketide-synthase
MGSSMDEVVDALRASLLENERLRQQNQRLTSASTEPLAIVGIGCRFPGGVHDPEDLWRLLVEGRDAMAGFPPDRGWDRWDVPTARSGAFLHDAGAFDPGFFRISPREAKAMDPQQRLLLETSWEALERAGIDPTTLKGSRTGVFVGGAPQEYGALVMNSREAAGGHVLTGAPGSILSGRISYVLGLEGPAVTIDTACSSSLVALHLAVKSLRTGECDLALVGGVLVMVTPQIFTEFESTGGSARDGRCKAFAASADGTGWGEGAGVLAVQRLSDARRDGHPVLAVIRGSAVNQDGASNGLSAPNGPAQQRVIREALANAGLAPADVDLVEAHGTGTTLGDPIEAEALLATYGQGRDAERPLWLGSFKSNIGHTQAAAGVAGVIKAVLSLRHGLMPKTLHVDEPTPQVDWSAGAVELLTEAREWPETDRPRRAGVSSFGISGTNAHVILEQAPEPDEPVTEPATGKDLPVLPWVLSGRTEAALRAQAGRLARHLRDHPDTAPADVALSLATTRAAFEHRAVVLGPDTHTLTTALDTLTTGTPGTGVITARATQTGSPAVFVFPGQGSQWAGMGRELWDTSPVFAETMAACERALAPWVEWSLRDVVSRPAEDALWQRVDVVQPVLWAVMVSLAALWRSYGVEPAAVIGHSQGEVAAACVAGGLSLEDGARVVAVRSRLVLERLSGKGGMMSVALPVGEVEELLAPWEGRVGVAAVNGPSSVVVSGDREGLDAVQGVCEEREIRARRIAVDYASHSAQVDALADDLLRELADIRPRSSSVAFYSTVTGGRLDTVGLDAGYWVRNLRERVAFEPVVRSLVERGSGVFVESSPHAVLTMAVAQTGDVVDRPVAVVGSLRRDEGGADRFVVSLAEAFVAGAAVDWSVLFAGSGARRVGLPTYAFQHERYWLDDVELPGAGSGEGVVDPVDAAFWGAVERADVEGVAALVEGAEAGVWEPVVPALSAWRRGRRARSTLDGWRYRTVWRSVSVPSSGALSGRWVVVARGEGEATTRVREALGSAGAEVTTVLADGEVDGEVFAGASGVVALLGLGDEDEAAAAVVRLVQAHARAGAEAPVWVLTRGAAAVGGADVVRPVAAQVWALGQVAGLELPGTWGGLVDVPEVWDERVAAHFVDVLAAGEGEDQVAVRASGVFGRRLVRAPLAGTAPSRSWSPRGTVLVTGGTGGLGAHLARWLAKEGAERLLLLSRSGDRAEGATELAREIEASGTAVELVACDVTDRDALAGVIGAVPAEQPLTAVFHAAGVSGYADLGDISPEHLDDVLSARVVGARHLDELTAGVELDAFVLFSSGAAVWGSAGNGANAAAGGYLDGLARERRTRGLTGTSVAFSGWRGTALERGETAAQLSRRGVRLLDAEPAGWALRRVLEADETSVTVADLDWSLFTPGYTLARRRPLIEDVPEAARALDDTDDASGAGDDGSAGAELRARLAALTETEQRSHLLGLVRGEAARVLAHASTTEITPARPFRDLGFDSLTAMELRNRLNRATGLRLPATLVFDYPDPQRLTGHLYEELVGGLAAPATDVTAATRAAADEPLAIVGMACRYPGGVRGADDLWRLLVENRDELSAFPTDRGWDGWGALTSGRAGFLHEAGDFDAGFFGISPREAAAMDPQQRLVLETSWEAVEAAGIDPQSLRTTATGVFVGGGPQDYPTVLAASAEAESGYAMTGALGSVISGRVSYALGLEGPAVTVDTACSSSLVALHLAAQALRNGECDLALAGGVTVMATPGAFAEFDTLGGMAGDGRCKAFSSDADGTGWGEGVGMLLVERLSDARRNGHEVLAVVRGTATNQDGASNGLSAPNGPSQQRVIRQALANAGLAPTDVDMVEAHGTGTKLGDPIEAQALLATYGQGRDADRPLWLGSIKSNLGHTGAAAGVAGVIKAVLSLRHGLMPKTLHVKEPTPQVDWSAGAVELLTENREWPATDRPHRAGVSSFGISGTNAHVILEQAPAGEPAADSERTGPAALSDAPVPWVVSGRTEAALRAQAERLRTHLADHPEATPLDVGHALVTARSGFEHRAIVLGTTAGELLDGLDTVARGTTTAHVIQGSGAASGLVFVFPGQGSQWAGMGRELWDTSPVFAESMAACERALAPWVEWSLRDVVSRPAEDALWRRVDVVQPVLWAVMVSLAALWRSFGVEPAAVIGHSQGEVAAACVAGGLSLEDGARVVAVRSRLVLERLSGKGGMMSVALPVGEVEELLAPWEGRVGVAAVNGPSSVVVSGDPEGLDAVQGVCEEREIRARRIAVDYASHSAQVDALAEDLLRELADIRPRSSSVAFYSTVTGGRLDTVGLDAGYWVRNLRERVAFEPVVRSLAEQEYGLFIETSPHPVVTMAVTETGDFIDTPVTAIGSLRRSEGGADRFLASLAEAYAAGAPVDWSVYFAHAAVKRVSLPTYAFQHRRYWLEDAAAPGTATTVDPVDAAFWGAVERADVEGVAALVEGAEAGVWEPVVPALSAWRRGRRAQSTLDGWRYRTVWRSVSVPSSGALSGRWVVVARGEDEATAEVREALESAGAEVTTVLADGEVDGEVFAGASGVVSLLALSGDEEAVSGTVSVVQAHARAGAEAPLWVLTRGAAAVGGADVVCPVAAQVWALGQVAGLEQADGWGGLVDLPGDWDQAAATGLTDVLAAGEGEDQVAVRSSGVFGRRLVRAPLAGAAPSRSWSPRGTVLITGGTGGIGAHLARWLAKEGAERLLLLSRSGERAEGATELAREIEALGTAVELVACDVTDRDALAGVIGAVPAEQPLTAVFHTAGIASYGTVRESGLTELAEQMAAKTLGARHLDELTAGVELDAFVLFSSGAAVWGSAGNAGYAAANGYLDGLARERRARGLAATAVSWGGWEATGMAGDGTAEQLSRRGVRAMDPELCLEALRQALEHDETALTVTDMDWEKFTPGYTLARRRPLIEDIPEVARVLREEADRTEDGDDSANSAFRSELTRLGEAEQHARLLDLVREEAAGILGHSSTAEITPQRPFKDLGFDSLTAMELRNRLNRATGLRLPATLVFDYPNPRQLAAQLRARLTGATAGETAAVVTVTRAVADEPLAVVGMACRYAGGVASPDDLWRVVVEGRDEMTDAPAHRGWDRWNVPSLRQAGFLHEAGDFDAGFFGISPREAAAMDPQQRLLLEASWEAVEHAGINPQSLQGSDTGVFVGGTAVEYGALLMNAPGSQGYAVTGSAGSVLSGRISYVLGLEGPAVSVDTACSSSLVALHLAAQALRGGECDLALTGGVGLMATPGAFAEFDTLGGLSVDGRSKAFAASADGIGWGEGVGMVVLERLSDARRNGHEVLAVIRGTAINQDGASNGLSAPNGPSQQRVIRQALANSGLTYADVDLLEAHGTGTKLGDPIEAQALLATYGQDRGTDRPLWLGSVKSNIGHTGAAAGVAGVIKAVLSLRHGLMPKTLHVDEPTPQVDWTAGAVELLTENREWPETDRPRRAGVSSFGVSGTNAHVIVEEAPQEGPAADAPAEPGDDDTTRAVPPLAPSLVPLVFSGRAAGALRGQAERLTAVLASDAAPGLTDVAFSLATTRATLEHRAVVLAASHPDGLDGLRAVARGETNPTALTGLADTGDHRVVFVFPGQGSQWAGMGRELWDSSPVFAESMAACERALAPWVEWSLRDVVSRPAEDALWQRVDVVQPVLWAVMVSLAALWRSFGVEPAAVIGHSQGEVAAACVAGGLSLEDGARVVAVRSRLVLERLSGKGGMMSVALPVGEVEELLAPWEGRVGVAAVNGPSSVVVSGDPEGLDAVQGVCEEREIRARRIAVDYASHSAQVDALADDLLRELADIAPRSSSVAFYSTVTGGRLDTVGLDAGYWVRNLRERVAFEPVVRSLVERGSGVFVESSPHAVLTMAVAQTGDVADRPVAVVGSLRRDEGGADRFVVSLAEAFVAGAAVDWSVLFAGSGARRVGLPTYAFQHERYWLDGVVIGDTSGGSADAVDAAFWDAVEREDLADLATVLETTGESAPGGTTGIDTWLPTLAAWRRGRRARSTLDGWRYRTAWRPVSVPAGGGLSGRWVIVTAAEDATAARVRKALTAAGAETETVATREPDLLAAEIAGASGVVSLLALGDRPVADTLTVVQAHADAGGEAPLWLLTRGAAGVTDEEAVRPEAAQVWALGQVAGLELAGAWGGLVDVPEEWDEAVATGLADVLAAGEGEDQVAVRASGVFGRRLVRAPLAGTAPSRSWSPRGTVLVTGGTGGLGAHLARWLAKEGAERLLLLSRSGERAEGATELAREIEASGTAVELVACDVTDRDALAGVIGAVPAEQPLTAVFHTAGAAAHGPLTELDPAALDEQLAARVAGARHLDELTAGVELDTFAVFSSGAAVWGSAGNGANAAAGGYLDGLARRRRARGLAAVSVSFSGWQGTALARGETAAQLSRRGVRLLPPELAGQALRQVLETDETSVTVADMDWSLFAPGYTLARRRPLIEDIPEVARVLQDAEREQEAAQDGSAGAELRARLAGLTEAERRSHLLGLVRGEAAQVLGHASTAEVTPARPFRDLGFDSLTAMELRNRLNRATGLRLPATLVFDHPSPQRITEHVLAELGKDGRGGLDDVLDIRRELGRIGEALDGVAADPGAREDIAGQLRDLLARLGAAERDATTDLDSASDDEIFDFIDRDLGVS
>NZ_CP010849.1|WP_044383940.1|5289506_5301338_+|type-I-polyketide-synthase
MANEQQLRDYLKKAGAELHRTRQRLSELEARTTEPIAIVGMACRYPGGVTTPEELWRLVADGVDAVGPFPTDRGWDLDTLYHPDPEHEGTCYAREGGFVEDIASFDAAFFGISPREAQSMDPQQRLMLETSWEALERAGIDIHALRGSRTGVFAGLNQQDYGTLLAAGPEGLDSYGSTGTSNSVLSGRVSYVLGLEGPAVTVDTACSSSLVALHLAAQALRAGECDLALAGGVTTLSTTAVHIALSGQRALAPDGRSKAFSADADGAGWSEGAGVVAVERLSDALRLGHPVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGVSPAEVDAVEAHGTGTSLGDPIEAEALLSAYGQARPADRPLWLGSLKSNIGHSGAAAGVGGVIKMVQALRHGVLPKTLHVTEPTPNVDWSAGAVELLTEAREWPETDRPRRAGVSSFGISGTNAHVILEQAPPPRPATAEDSTGEDATAGDATGADTAGREAAPGRSGAAVPARLPWLLSARGDTALRAQARALRERLLADPAPTDADVAYSLATTRTPLDRRAAVLAADREGFLRALRALAEGQDTDGVLLGDPAPGKVVFVFPGQGSQWTGMARELLDASPVFAGTAARCAEAIARYVDWDPMDVLRGAPGAASLERIEVIQPVLFTVMVSLAELWRSYGVRPDAVVGSSQGEIAAAHVAGALDLDDAARIIALRSRLLAETLVGKGAVAAVALPVAEVEERLARWPGRLSVSGVNGPRSVAVAGEGAALEEFVAACQEDDVRARVVAATVPTHCALVDPLRERLLELLAPVTPRRGGVPLYSTVTGGLIDTATMDAEYWYRNTREPVLFEPVVRALLADGHRAFVESSPHPVLSLGVEQTIDATGVHAVTLETLRRDEGGPDRMVASLARAHLGGVRVDWPAVFAGTGARRTDLPTYAFQRTRYWAETRGASGDVGSVGLASLNHPLLGALVRMAGGDGVVLTGRLSRHLQPWLAGHTVAGHTVFPGTGFLELAVLAGDQAGCDRIDRLTVHTPLVVPPTGALVVQVHLEAADDTGARPLSVHTRPEDAAVDGVWTRHATGVLRPAEAAEAPGTPGTWPPEGAEPVALDGLYERLAGAGQEHGPDFRGLHAVWRAGDDICADVHLPADRQAEAGRYGLHPALAAAALLAVPAAAGGDTAAVQPADWSGVRLHATGSGRLRARLTRRADDVYALLLADGTGRPVLTADSLTLRPVDAAGLRTARADALFAVDWPETPVTGDTPPCVVLGADPFGLTAALPGARPAADLDALAGPAGADGTPEVLLPLAGDGPHAAGDLVSRALTALQSWLERPGDGRLTVVTRGAVATAPGEDVTDLAAAGVWGLLRSAQNEHPGRFAVVDLDADPASLARLGAALACGEEQLALRTGTARVPRLRRFDREGALLPPAAPAWRLAATGPGTPPGPGLAEDLEASAPLGPREIRIAVRAAALTGADLDPAPGTGLGGGLAGTVTETGADVVGLAVGDRVFGPAPGAAATSAVTDERTVRPVPEGWSDARAAAVAATHPAAYHALVDLGGPTAGRRVLVHDAGSGVGAAAVRLARHLGAEVFATAHPDTWPALREAGLDGAHLADSRTAEYEAWFRDAAGDRGMDLVLTGPARDHTDADLRLLAPGGVLVRTGTDGADPADRPGEPDATAAPDAARRRGDLAAAGPDRTGELLDTVTALLTAGTLPPPPVTVRDAREAPSLLRRLAEGTLGAEAVLTVPAAPWPAHGTVLITGGTGMLGALVARHLVTEHGVRSLVLTSRRGADAPGAAELRDELTAAGAEVTLAACDVADRAQLADLLGRIPADRPLTGVVHTAGALDDGMIESLTPERVHGVMGPKVTGALNLHELTEGLELTAFVLFSSMAGTMGAPGQGNYAAANAVLDQLAAHRRARGLPGTSLAWGFWAQRSEMSGHLDDRDLRRMGRGGVLPLSTYEGLAVFDVSCRTGRAQLVPARLDPAALAGPGTPAHGAHPVPPVMRALVPAPVRRAAGRGTDTAGDTLRDRLTGLTRTEQSGALLHLVRTTAATVLGHADADAVASATPFRDLGFDSLTAVEFRNRLAAAAGTRLPATVVFDHPTPTALAAFLARELLGDLAAEEAPRARTAARTAPADDDPLVIVGMACRFPGGVGSPGHLWDLVLSETDAVAGFPADRGWDTEPPADGSAPRQGGFLDGVAEFDAGFFGISPREALTMDPQQRLLLETSWEALERAGIAPDSLRGSRTGVYVGAVSSGYTTLFPEGSESLAGYVVTGASTSVISGRVAYVLGLEGPAVTIDTACSSSLVALHTAAQALRSGECDLALASGVAVMTSPFLFDDFAKQGGLAPDGRCKAFADAADGTSWAEGAGTVVVERLSDARRNGHPVLAVVRGSAVNQDGASNGITAPNGPSQQRVIEQALANCGLGAADVDAVEAHGTGTTLGDPIEAQALLATYGQGRDAERPLWLGSFKSNIGHSQAAAGIAGVIKTVESLRHGVLPRTLHVDAPSSHVDWDAGHVALLTETRPWPETGRPRRAGVSAFGISGTNAHLILEQAPDEPVPAPAAPLPLTPWVLSAQDEPALRAQAARLLDHLTEHPHTDATDIAYGLATGRAALAERVGFPADDRAEALDVLAALAAGRTPPAAVRGTAGEGSLAFLFTGQGSQRPGMGSGLYAAFPAFAAAFDAVCAEVDPLLGRPLRATVFEGEAAGLDRTAITQPALFALEVALFRLLESLGIHPDYLLGHSVGEIAAAHVAGVLSLPDAARLVVARGRLMQDLPPGGAMLAVEATEEEARAALSEILDTDTDTDTDTDADDGASATVGLAAVNGPRAVVLSGAAEPVERLARHFGAEGRRTRRLDVSHAFHSPLTEPMLEEFAEVVAALSFAPPRIPVVSNVTGRVVGAAEIATPGYWVRHARQTVRFAQGVATLTEAGVTGFLELGPDGVLTALTESCLPAAPAGVCVPVLRRDRDEARTLLTAVTAAHTHGVRVDWEAVFAGTGAHRPGLPTYPFQHRSYWPPATRTGRGDLSAAGLDDTGHPLIGTMVRSAAGGDVLFTGEVSLAGQPWLADHAVWGSPLFPGTGFLELALWAGGHLGAGTVDELVVHSPLVLPERGRVTLQVVVSGTEEDRRTVTVHSRPAGTTAWTRHAEGVLIADTPAQPPAPAPVWPPEDAEPVELTGFYDDLLGTGMAYGPAFQGLARAWRRDGEVYAEAALPAGPDAAKEFGAHPALLDAALHTLAFLPSAQGADGPHLPFSWRGVSLHATGAGTCRIRLAPGETPQEVTATLWDDTGRPLVHVEGLTLRQTSRAQLGAASAVTSLYRTEWTALTGSAPAAPQAAWAVLGTDGPDLPGSPRHAGLDALGDADTAPDYALLTCPPATGSGPAAVREAVHHALGLLRDWTADDRFAATKLVLCTRGAAADVPDPAHAAVWGVARSAQLEHPGRLLLADLADDGQVAGLPRAVALAEAADEPQFALRDGTVLVPRVTRAAAPDRAAAPDWPTQGTTLVTGATGMIGSLIARHLVREHGVRDLLLISRSGERAPGAAELAAELTAAGATVRIAACDAADRSALAAVLAAQPADRPVTAVVHAAGVVDDGLLGSLTPEQVDRVLRAKVDAAAHLHDLTADGDLRAFVVCSALAGTLGGGGQAAYAAANASLDALCARRRAAGLPALALAWGPWESTGGMTAQLTAADLKRIARAGMHPLDAAEGLALFDAARAHGDAVLLPFRFDAAGLSEADRAALPPALRGLAPRPRRRTGRAATATAGLAERLRPLSAEDRLTTLENLVRAEVAAVVDLPSADAVPVTKAFKSLGFDSLMAVELRNRLSAVTAVRLPATLVFDHPNSRALAAHLLDGLALEEGTGESDPALLALRGLESAVRSLAPGAGDRTALATRLRVLLAAVEDPGTGPGAADGDDDTGDRDIEAASAEELVSLLGSEFGIS
>NZ_CP010849.1|WP_078969291.1|5349809_5350754_+|3-hydroxybutyryl-CoA-dehydrogenase
MAHPLRTTADAGPAGERPRPEDTDDAAAAARAILRVGVVGCGVMGAGLAEVCARAGRDVRVAGSGPEGLARGRARLERSLAAAVRKERITAADRDAALARVTFTTDLGDLRDRQLLLEATPEHEPTKLRVFAALDEIVEDPGAILATNTSALSIMRIAGATGRPGQVLGLHFFNPAPVLPLVEVIGSLLTAERTRRVAGEFVTSVLGKQAVHAADRSGFVVNALLIPYLLSAIRMYESGFAAAEDIDKAMTLGCSHPMGPLALSDLIGLDTVAAIADALYKEFAEPTHAVPPLLSRMVDAGLLGRKTGRGFFRY
>NZ_CP010849.1|WP_029382921.1|5351076_5351490_+|hypothetical-protein
MQSHDVRTLLHCSLPTVAAGAVGVAVSAAVAGGKGAIGAAAGTLLVVLFMTSGLVVLQRTARTLPHLFQMMGLLVYTTQILLLMVVLTTLRSTSAFNPKCFAFTLLAATLVWIGAQVRAHMKAKILYVEPDSARTTS
>NZ_CP010849.1|WP_029382920.1|5351727_5352522_+|F0F1-ATP-synthase-subunit-A
MLAFETDCHIFEGCGFPTPGLHSFLFKPMFTVAGIEFNKPILLALLSTVVVIGFFWAAFRKPQIIPGKLQMIGEAGYDFVRRGVVYETIGKREGEKYVPLMVSLFFFIWIMNLWAIIPLAQFPVTSVIAFPAGLAALVYILWVSLTFKRHGFVGGWKNITGYDKSLGPVFPMVMFFEFLSNLLIRPFTHAVRLFANMFAGHVLLLIFTIGTWYLLNGIGIAYSAVSFVMVIVMTVFELFIQALQAYVFILLSCSYIQGALAEHH
>NZ_CP010849.1|WP_029382919.1|5352591_5352840_+|ATP-synthase-subunit-C
MSALQTLAATNIQGNFAAIGYGLAAIGPGIGVGVIFGNGTQALARQPEAAGLIRQNQILGFVLCEALALIGLVMGFVYPVPS
>NZ_CP010849.1|WP_078648142.1|5352894_5353443_+|F0F1-ATP-synthase-subunit-B
MVQLAAEEEAQNPLIPAIPELVIGLIAFAIVFFVLGKKLLPNINKVLEQRREAIEGGIEQADAARTEAQSVLEQYKAQLAEARHEAARLRQEAQEQGAALIAEMRAEGQRQREEIIAAGHAQIEADRKAAASSLRQDVGKLATELAGKLVGESLEDHARQSRVIDRFLDELDDKATKAEATR
>NZ_CP010849.1|WP_044383953.1|5353439_5354255_+|F0F1-ATP-synthase-subunit-delta
MNGASREALAAARERLDALTDSTSVDAARLADELAAVTALLDREVSLRRVLTDPAQAGEAKAELVQRLLAAQVSGPAADLVSGMVRTRWSQSRDLVDALEELADTADLTAAQKDGTLDDVEDELFRFGRIVSGSTELRAALTDRTATASAKAALMHSLLGGRAKPGTERLVTRLVTAPRGRSLESGLESLSKLAADRRNRMVAVVTSAVPLSDIQKRRLGATLAKLYGRPMHLSLDVDPEVLGGIRVQVGDEVINGSIADRLEDAGRRMAS
>NZ_CP010849.1|WP_029382916.1|5354391_5355999_+|F0F1-ATP-synthase-subunit-alpha
MAELTIRPEEIRDALENFVQSYKPDAASREEVGTVTLAGDGIAKVEGLPSAMANELLKFEDGTLGLALNLEEREIGAIVLGEFSGIEEGQPVTRTGEVLSVAVGEGYLGRVVDPLGNPIDGLGEIETEGRRALELQAPTVMQRKSVHEPMETGYKAVDAMTPIGRGQRQLIIGDRQTGKTALAVDTIINQRDNWRTGDPKKQVRCIYVAIGQKGSTIASVRRALEENGALEYTTIVAAPASDPAGFKYLAPYTGSAIGQHWMYQGKHVLIIFDDLSKQADAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDMGAGSMTGLPIVETKANDVSAFIPTNVISITDGQCFLESDLFNAGQRPALNVGISVSRVGGSAQHKAMRQVSGRLRVDLAQFRELEAFAAFGSDLDAASKAQLERGQRMVELLKQNQYEPMATEDQVVSIWAGTTGRMDDVPVADVRRFEKELLDYLHRKEQGLMTSIREGAKMSDDTIQAIADAVAEFKKQFETSDGKLLGEEASAAPKATSASK
>NZ_CP010849.1|WP_029382915.1|5356020_5356938_+|F0F1-ATP-synthase-subunit-gamma
MGAQLRVYKRRIRSVTATKKITKAMEMIAASRVVKAQRKVAASTPYARELTRAVTAVGTGSNTRHALTTEAENPTRAAVLLLTSDRGLAGAFNSNAIKAAEQLTERLEREGKQVDTYIVGRRGVAHYNFRERKIAESFTGFTDEPTYADAKKIAAPLIEAIQQETADGGVDELHIVYTEFVSMMTQTAVDSRMLPLRLEEVAEETAPKGEILPLYDFEPSAEDVLDALLPRYVESRIYNALLQSAASKHAATRRAMKSATDNAGELINTLSRLANAARQAEITQEISEIVGGASALADATAGSDN
>NZ_CP010849.1|WP_044383956.1|5356937_5358386_+|F0F1-ATP-synthase-subunit-beta
MTTTVEPTAPAGVATGRVARVIGPVVDVEFPVDAMPEIYNALHVEVADPANAGELKTLTLEVAQHLGDGLVRTISMQPTDGLVRQAPVTDTGSAISVPVGDFTKGKVFNTLGEVLNVDESYDGERWPIHRKAPNFDELESKTEMFETGVKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMIYRVANNHDGVSVFAGVGERTREGNDLIDEMSESGVIDKTALVFGQMDEPPGTRLRVALAGLTMAEYFRDVQKQDVLFFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPNLADEMGLLQERITSTRGHSITSMQAIYVPADDLTDPAPATTFAHLDATTVLSRPISEKGIYPAVDPLDSTSRILDPRYISADHYNAAMRVKNILQKYKDLQDIIAILGIDELGEEDKLVVHRARRVERFLSQNTHVAKQFTGVDGSDVPLDESIAAFNAICDGEYDHFPEQAFFMCGGIEDLKKNAKELGVS
>NZ_CP010849.1|WP_029382913.1|5358497_5358872_+|F0F1-ATP-synthase-subunit-epsilon
MAAELHVALVAADREVWSGQATLVIARTTSGDIGVMPGHQPLLGVLESGPVTIRTSDGGTVVAAVHGGFISFADDKLSLLAEIAELSDEIDVQHAERELERAKAEGDTVAERRADVRLRAAAAR

Crispr_ID: NZ_CP010849_20

• CRISPR_ID: NZ_CP010849_20
• CRISPR_location: 5383042-5383248
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP010849_20

Consensus_repeat	Method
CAGCTGCTCGGCCTCCGCGCGGGC	CRISPRCasFinder

spacers of NZ_CP010849_20

>20.1|5383066|51|NZ_CP010849|CRISPRCasFinder
CTCGCGCAGCGCCGTGTCGGCCTCGGCCATGCGCTGCTCGGCGGCCCGGCT
>20.2|5383141|30|NZ_CP010849|CRISPRCasFinder
GGCCTCCGACTCGGTGGCGGTGGTGGTGCG
>20.3|5383195|30|NZ_CP010849|CRISPRCasFinder
CTCCTGGGCCTGCGCCGAGGCGGCGTTCAG

CRISPR arrays and Neighbor proteins around NZ_CP010849_20

CRISPR arrays

The CRISPR arrays of NZ_CP010849_20

>merge|NZ_CP010849|20|5383042-5383248|CRISPRCasFinder
CAGCTTCTCGGCCTCGGCGCGGGCCTCGCGCAGCGCCGTGTCGGCCTCGGCCATGCGCTGCTCGGCGGCCCGGCTCAGCTCCTGGGCCTGGCGGCGGGCGGCCTCCGACTCGGTGGCGGTGGTGGTGCGGAGCTGCTCGGCGTGGTCGGTGGCCTCCTGGGCCTGCGCCGAGGCGGCGTTCAGCAGCCGCTCGGCGTCCGCGCGGGC

>NZ_CP010849|20|19|5383042-5383248|CRISPRCasFinder
CAGCTTCTCGGCCTCGGCGCGGGC	CTCGCGCAGCGCCGTGTCGGCCTCGGCCATGCGCTGCTCGGCGGCCCGGCT
CAGCTCCTGGGCCTGGCGGCGGGC	GGCCTCCGACTCGGTGGCGGTGGTGGTGCG
GAGCTGCTCGGCGTGGTCGGTGGC	CTCCTGGGCCTGCGCCGAGGCGGCGTTCAG
CAGCCGCTCGGCGTCCGCGCGGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044383999.1|5384132_5384573_-|methylmalonyl-CoA-epimerase	unknown	unknown	gnl|CDD|213772
NZ_CP010849.1|WP_044384009.1|5390092_5390569_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP010849.1|WP_044383995.1|5375621_5376857_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213235
NZ_CP010849.1|WP_044383991.1|5374407_5374740_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044383988.1|5373129_5374158_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NZ_CP010849.1|WP_044384015.1|5392108_5392741_-|AIM24-family-protein	unknown	unknown	gnl|CDD|376704
NZ_CP010849.1|WP_044384003.1|5387168_5387846_-|peptidase	unknown	unknown	gnl|CDD|377032
NZ_CP010849.1|WP_044384005.1|5387963_5388686_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP010849.1|WP_029382898.1|5372656_5373049_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044383983.1|5368944_5371572_+|ATP-binding-protein	unknown	unknown	gnl|CDD|223021
NZ_CP010849.1|WP_029382887.1|5385978_5386935_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|224617
NZ_CP010849.1|WP_029382891.1|5378793_5379732_-|cellulose-binding-protein	unknown	unknown	gnl|CDD|274008
NZ_CP010849.1|WP_078969292.1|5384721_5385927_+|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|180261
NZ_CP010849.1|WP_044383986.1|5371693_5372365_-|endonuclease-NucS	unknown	unknown	gnl|CDD|235114
NZ_CP010849.1|WP_044388375.1|5376968_5377739_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|372253
NZ_CP010849.1|WP_044388377.1|5377741_5378707_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213235
NZ_CP010849.1|WP_044383993.1|5374755_5375625_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|372253
NZ_CP010849.1|WP_044384007.1|5388682_5390089_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP010849.1|WP_044384013.1|5391456_5392107_-|AIM24-family-protein	unknown	unknown	gnl|CDD|376704
NZ_CP010849.1|WP_044384011.1|5390662_5391454_-|Ser-or-Arg-related-nuclear-matrix-protein	unknown	unknown	gnl|CDD|376704

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044383999.1|5384132_5384573_-|methylmalonyl-CoA-epimerase	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	1.50595e-49
NZ_CP010849.1|WP_044384009.1|5390092_5390569_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	7.34017e-14
NZ_CP010849.1|WP_044383995.1|5375621_5376857_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	1.45903e-95
NZ_CP010849.1|WP_078969292.1|5384721_5385927_+|acetyl-CoA-C-acetyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP010849.1|WP_044383988.1|5373129_5374158_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	5.04612e-56
NZ_CP010849.1|WP_044384015.1|5392108_5392741_-|AIM24-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	3.36948e-38
NZ_CP010849.1|WP_044384003.1|5387168_5387846_-|peptidase	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	4.88781e-08
NZ_CP010849.1|WP_044384005.1|5387963_5388686_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.67979e-83
NZ_CP010849.1|WP_044383983.1|5368944_5371572_+|ATP-binding-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	1.40794e-09
NZ_CP010849.1|WP_029382887.1|5385978_5386935_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|224617	COG1703, ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism].	1.84621e-121
NZ_CP010849.1|WP_029382891.1|5378793_5379732_-|cellulose-binding-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	7.39942e-07
NZ_CP010849.1|WP_044383986.1|5371693_5372365_-|endonuclease-NucS	gnl|CDD|235114	PRK03298, PRK03298, endonuclease NucS.	3.76769e-178
NZ_CP010849.1|WP_044388375.1|5376968_5377739_-|ABC-transporter-permease-subunit	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	0.000139269
NZ_CP010849.1|WP_044388377.1|5377741_5378707_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	6.60201e-95
NZ_CP010849.1|WP_044383993.1|5374755_5375625_-|ABC-transporter-permease-subunit	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	0.00100402
NZ_CP010849.1|WP_044384007.1|5388682_5390089_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.26262e-45
NZ_CP010849.1|WP_044384013.1|5391456_5392107_-|AIM24-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	9.18627e-40
NZ_CP010849.1|WP_044384011.1|5390662_5391454_-|Ser-or-Arg-related-nuclear-matrix-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	1.47075e-07

Protein sequences

>NZ_CP010849.1|WP_029382891.1|5378793_5379732_-|cellulose-binding-protein
MSDTSPYGFELVRRGYDRAQVDERISKLVSDRDSALARITALEKRIEELHLETQNAQAQISEAEPSYAGLGARVEKILRLAEEEAKDLREEARRAAEQHRELAESAAQQVRNDAESYAAERKAKAEDEGVRIVEKAKSDAAQLRAEAQKDAQSKREEAEALFEETRAKAAQAAADFETNLAKRREQSERDLASRQAKAEKRLAEIEHRAEQLRLEAEKLRTDAERRARQTVETAQRQAEDIVADANAKADRIRSESERELAALTNRRDSINAQLTNVREMLATLTGAAVAAAGTPSTDDESTSRGVPAQQTR
>NZ_CP010849.1|WP_044388377.1|5377741_5378707_-|ABC-transporter-ATP-binding-protein
MIELEGLTKRYGEKVAVNNLTFAVRPGIITGFLGPNGAGKSTTMRMVLGLDRPTAGDVRIDGNHYDELKDPLKYIGALLDAKAVHGGRSAYHHLLCLAQANGIPAKRVHEVLDVVGLTAVAKKKAKGFSLGMGQRLGIAAALLGDPRILMFDEPVNGLDPEGIHWIRNLMKALAAQGRTVFVSSHLMSEMALTADHLVVIGQGRLLADTSMADFIAQNSRSYVRIRTPQREQLLDVLNEAGITVAGSGSEVLEVDGDKSERIGELAAQHQIVLHELSPQQASLEEAFMRLTAESVEYHAHGGQPAGQRQAQQEWGSEWRRG
>NZ_CP010849.1|WP_044388375.1|5376968_5377739_-|ABC-transporter-permease-subunit
MATAQVVRSEWTKIRSVASTVWTLSLAVVVTIALGMLISALSKSEYDNMSARDRLSFDPTFISFAGMSLGQLAMIVFGVLVVANEYSTGMIRTSLAAVPQRGAFLFGKISVATLLALAVGMATSFAAFFLGQAMLGDLKASLGDPGVLRAVFGGGLYMTLIAMFSMGVAAMLRSPMLSLGILMPFFFLISNILSAVDATQKVGRFLPDQAGSKIMQVVPPVGDDTPYGPWGGLGIMVLWVVAALIGGFLVLKRRDA
>NZ_CP010849.1|WP_044383995.1|5375621_5376857_-|ABC-transporter-ATP-binding-protein
MIEAVGLTKRYGDKTAVYNLSFQVRPGAVTGFLGPNGSGKSTTMRMILGLDNPTSGRVTIGGYPYRKLPNAPRQVGALIDAKAVHGGRSARNHLLSLAQLSGIPARRVDEVLGVVGLQDVARKRSKGFSLGMGQRLGIAAALLGDPQVLLFDEPVNGLDPEGILWVRNLMKALAAEGRTVFVSSHLMSEMALTADHLIVIGRGQLLADMSVKDFISANSADFARVRTPDTEPQLREKLTIALTEAGGQVLPEQDGALRVMGLALPRISDLAHEAGVRLWELSPHQASLEEAYMRMTQGVVDYRSTADQKAGLQQPLPPGAQPPMPVPGQGQPGWYAPPPPQHAAPHPGGTPANPYGGPGAAPRPPAGPALQGQAPGQPPSGAPAAPAAAPAASAAASPAPVTDPTTSEDAR
>NZ_CP010849.1|WP_044383993.1|5374755_5375625_-|ABC-transporter-permease-subunit
MSTPQPPMPQAAPDRQAAPGPSFPSYASPIPVVRTHLGHAIASEWTKMKSVRSTMWTLGVFVLLVVGIGLLAGAVVAGSPSDLSGENALSLGLFGLLLGSMCIITLGVLTTASEYGTGMVRTTMTACPSRGRVLAAKAVVFFLVAFVVTLVSSSLVAVAHVAMLEGNGAAEPTGGEWLKATVGISLYIALLGLLSLAVGSIVRHSAGAITVMIGTVLAPLVIALFMFARSLEGVRQALLEYSIPNQLSVFYTQSLSDSGPSGWDPLWIALGVTAVAFAGAYALLEKRDV
>NZ_CP010849.1|WP_044383991.1|5374407_5374740_+|hypothetical-protein
MSPRRNRPKGAGSSGRSAEDDRPGRYGGWQSSESWQGEEWSVRHVAGASARGKAYRCPGCDQLIPDNVPHVVAWAQHAGVDDRRHWHRSCWNAKDRRTTRVQRSRNAPRF
>NZ_CP010849.1|WP_044383988.1|5373129_5374158_-|LLM-class-flavin-dependent-oxidoreductase
MRVGSFVLAAQFPGQGQGEPLHRAVRSAEVAEEAGLDSVWLAEHHFVPYGTCPSAVTLAALLLGRTRRIRVGTAVSVLPATHPVALGEQAALLHLTSGGRFSLGVGRGGPWVDLEVFGAGLEAYERGFPESLDLLMRWLREPSVSADGERFRFREVPVVPRPSESLTDAPGPEVVVACTSPASVRLAAERGLPMLLGMHVGDEEKAEMVGLWQRHAQDCGRPWEEVYGAAHVSAGVCQIADRRADAAEALLKSMPGWLRQGLDAHVTVDGRARQMRDPLAYTELLCGLHPVGTPRLCADRLSATSERTGITRFALLAEGSGDLAATEDNLRRLGTEVLSQLR
>NZ_CP010849.1|WP_029382898.1|5372656_5373049_+|hypothetical-protein
MSLDVSPALLEQAERGEVDEADFVDCVRTSLPYAWEMISSLVAQLKVDGGAFADNQTPPPDEQARGQLLRALASDAIRGALQRHFGVRLAFQNCHRVAVFPLDSSVDETLARFTSIRGQLLNQSPELRDC
>NZ_CP010849.1|WP_044383986.1|5371693_5372365_-|endonuclease-NucS
MRLVIARCSVDYAGRLTAHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCTLKEGTGDDEGVWTVVNKAGEKLIITMEEILHDSTHELGVDPGLIKDGVEAHLQELLADRIETLGEGYTLIRREYPTAIGPVDILCRDADGQTVAVEIKRRGEIDGVEQLTRYLDLLNRDPHLAPVRGIFAAQEIKPQARVLATDRGIGCQVLDYDALRGIEDDKLRLF
>NZ_CP010849.1|WP_044383983.1|5368944_5371572_+|ATP-binding-protein
MDPNTRGPEDHGHDDGSTARSSGFDTGGGDAPRQRPPRESLMSDFGQHAPALARTVQLVSGEYLLTVNPVDGSEIELCPPGERPASPEKFTTAERAEADRASKPPVPAGPSRPALPLVARQDERERLVRLLARGRSVRLTGSAGAGRTSLLDLVAEDCADLAPDGVVRLSGFRRTADELLYDLFYAVHRASGHRPEREELLPHVREIGAVVVLDDIEFGGAALDELLDATPECAFLIGATPDVPAPSAGSAVEEVFLTGLERADSVELLERAAGRPLTEEEANWAGDLWFESEGLPLRFVQAGALLRQRDRLRAGAEAVDGDGAFADAAPRDAAGNDTVSLPSLGEAAGPAPLLASRLSSSARATLEFAVALGGEVPHQAHLPALVGDTHADAALGELADCGLVSPVGARYRLAAGVLAQLEAAGYADDVLGRALSAARHYAWWAGHPSVTPERVCAEADAVLAALAVLAPATTPPAEDAESPAVALARTAAPAFAAGLHWSAWERALRCGAEAARLAGDVAEQAYFHHELGVLALCQGHLDRARAELEASIGLRGALADKRGTVAGRRALALVADRSGDTPGLGIETTTPLPGVAAAGFASAGDEAPGAPREEPDPPTKVVPAAFPPLKPPTRSSAPATRPTASPGTSRAARGGIKGFARRNLVATGAGALLVAVLGTVVTLGATSDNEGGTPSDRVGVNPSASQGAGDDGQGVDRADDDGDGKGTGGDGPVARPTDPGPDGTLGTADDPTPTSSGRASDGPGGTREPDDPGDPTSGEPPASGKPPTSGKPPTSEEPPSSEPPASEEPPSSGPSTPEEPTTPEEPPTSEEPPSSEPPPPSTTDSASGPAPSASATTASAPGGGGAPGSASSTLI
>NZ_CP010849.1|WP_044383999.1|5384132_5384573_-|methylmalonyl-CoA-epimerase
MLTRIDHIGIACHDLDTTVEFYRATYGFEVFHTEVNEEQGVREAMLKINDTSDGGASYLQLLEPIREDSAVAKWLAKNGEGVHHIAFGTADVDGDAAAVRDKGVRVLYDEPRRGSMGSRITFLHPKDCHGVLTELVTSAPVEAPEH
>NZ_CP010849.1|WP_078969292.1|5384721_5385927_+|acetyl-CoA-C-acetyltransferase
MSSATNGTTSVIVAGARTPMGRLLGSLKSFSGADLGGFAIKAALDRAGIGGDQVQYVIMGQVLQAGAGQIPARQAAVKAGIPMNVPALTINKVCLSGLDAIALADQLIRAGEFDIVVAGGQESMTNAPHLLPKSREGFKYGAVQMLDAMAHDGLTDSFEGIAMGESTEKHNTRLGIGREEQDAVAALSHQRAAAAQKNGIFEAEITPVEIPQRKGDPVLFSKDEGIRADTTAESLGKLRPAFSKDGTITAGSSSQISDGAAAVVVMSKAKAQELGLDWIAEIGAHGNVAGPDNSLQSQPSNAIMHALKKEGLEVSDLDLIEINEAFAAVAVQSMKDLGVSSEKVNVNGGAIALGHPIGMSGARLVLHLALELKRRGGGVGAAALCGGGGQGDALIVRVPKA
>NZ_CP010849.1|WP_029382887.1|5385978_5386935_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MQDVSTLVAQAREGRPRAVARLISLVEGASPQLREVMAALAPLTGGAYVVGLTGSPGVGKSTSTSALVTAYRKQGKRVGVLAVDPSSPFSGGALLGDRVRMSEHASDPGVYIRSMATRGHLGGLAWAAPQAIRVLDAAGCDVILVETVGVGQSEVEIAAQADTSVVLLAPGMGDGIQAAKAGILEIGDVYVVNKADRDGADATARELNHMLGLGESRGPGDWRPPIVKTVAARGEGVDEVVEALEKHRAWMEERGVLAERRLARAAREVETIAVTALRERIGDLHGDRRLGALAERIVAGELDPYRAADELVTGLTRG
>NZ_CP010849.1|WP_044384003.1|5387168_5387846_-|peptidase
MKRNIVIAAVTAAALITGGTATALAVSGNDGGTARQGETRVSDDDAVRGEDARDDDRDERAVSSRVTAADAIAAALRHTPGTAVSAELEDADDADDGEKAAWDVDVLSGGGTWHSVRVDPATGKVLGSHADDDGDDDTAEVRAALKGTSVSAAEAARAAAVHGTVTSVDLDDDDRRSAAWDVETRSGAKAERDWTVDPGTGKVAADRSDDGADGADDDANDGDDD
>NZ_CP010849.1|WP_044384005.1|5387963_5388686_+|response-regulator-transcription-factor
MRPPVTHHHLAGGAPRRPSRILIVEDERRLALSLARGLTAEGYAVDVVHDGREGLHRAGEGVYDLVILDIMLPGLNGYRVCAALRAAGHDVPILMLTAKDGEYDEAEGLDTGADDYLTKPFSYVVLVARVKALLRRRAQGPGASPVVVHGDLRVDTAARRVFLGEDEVTLTAKEFAVLEQLVVRAGAVVSKSEILEHVWDFAYDGDPNIVEVYISALRRKLRHGLIGTVRGAGYRLETDR
>NZ_CP010849.1|WP_044384007.1|5388682_5390089_+|HAMP-domain-containing-histidine-kinase
MRRLFGSVRARATLAATLVVAVALVAAGTAVLLSLRSNLLGEAGTQAERSARAVASELAAGTPYDKLTLDDDDRPVQVVDEDGRLVAASEDLERISGTGVGAVTPRPEAAGRGDDEDDDSGEELEPGEIGELTTVGDGSATIDGDPADYRFVEVPVQTPDRGTLTVYAGAPLSAEHGAVRTALTVMLIGFPLLLAVVAVVTWLVTRRALRPVEGIRREMAEITRSEDLARRVPVPDTHDEVARLALTTNETLAALETSVERQRRFVADASHELRSPIASLRTQLEVGAAHPELLDLDGAVEDTVRLQRLAADLLLLARLDAGERPADARVDLAALAREEAGVRAGVRVRTEEGVAVAGSRGQLERVLANLLDNAQRHARSVVEVSVRREGAWAVVGVADDGEGVPVAERERIFERFVRLDAARSRDDGGAGLGLAIARDVAVRHGGTLTVRDAPAGGALFELRLPGSR
>NZ_CP010849.1|WP_044384009.1|5390092_5390569_-|MarR-family-transcriptional-regulator
METETAPRWLTDTEQCAWRTHLEVNKLLTYQLEKDLQPFGLTMNDYEILVNLSESEGVRMRMSDLASATLQSKSRLSHQITRMENANLVRRENCESDRRGLYAVLTEHGLETMKKVAPHHVASVRRHFIDLLSPEALTELDKALKPIAEHLRGQRGRP
>NZ_CP010849.1|WP_044384011.1|5390662_5391454_-|Ser-or-Arg-related-nuclear-matrix-protein
MYGTPGGPAVHDPATLPSDDSVDAYTFCVELDGSQWFLQKGKMIAYYGSIEFDGIGHGRLDRLIRTSFHSPLHAGDWVVARGSGKMLLADRAFDVNSYDLEDGNLTIRSGNLLAFQPSLALKQSIVPGFLTLIGTGKFVAASNGPVVFMEPPIRVDPQALVGWADCPSPCHHYDHGYMTGVLGGLRALTGLGGASGEEHQFEFVGAGTVLLQSSETLMSEQVTGAVPPDAGVPGGGGHGGPGQQSGAPRLPGQLGDLQRRFGL
>NZ_CP010849.1|WP_044384013.1|5391456_5392107_-|AIM24-family-protein
MGFREINPKMVEATVAPGRRLFSQRGAMLAYRGDVSFTPSVTGGQGGVMSMIGRRVADEDTPLMTVEGSGTVLFGHGGHHVQVIRLSGDTLYVEADRLLAFEGTLEQRTVFLGSQGGVMGMVRGQVSGQGLFTTALSGHGAVAVMAHGGVFEVPITPQRPVHVDPQAYVAHHGDVRNKLSTALGWRDMVGRGSGEAFQLELSGSGTVYVQASEEKL
>NZ_CP010849.1|WP_044384015.1|5392108_5392741_-|AIM24-family-protein
MFRLQSSKVLAVEMTGDAVKAKNGSMVAYDGEMAFKKLSGGGEGIRGMVTRRLTGEQMTMMEVKGHGTCWFADRASEINLVALQGDRLYVEASNLLAADASLRTGTGFTGMRGASQGNGLFTTTVEGHGQAAIMSDGPAVVLRVSARYPLTVDPGAYVAHQGDLRQSFQSGVTFRTALGEGGGEAFQIRFEGDGLVYVQPSERNTIAGDV

Crispr_ID: NZ_CP010849_21

• CRISPR_ID: NZ_CP010849_21
• CRISPR_location: 6767499-6767639
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP010849_21

Consensus_repeat	Method
GCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA	CRISPRCasFinder

spacers of NZ_CP010849_21

>21.1|6767542|55|NZ_CP010849|CRISPRCasFinder
GGCCACGGGTTTCTCGCGGCACGCAGCAGGCCCGCCGCGACGGGGGACGCGCGGC

CRISPR arrays and Neighbor proteins around NZ_CP010849_21

CRISPR arrays

The CRISPR arrays of NZ_CP010849_21

>merge|NZ_CP010849|21|6767499-6767639|CRISPRCasFinder
GCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAGGCCACGGGTTTCTCGCGGCACGCAGCAGGCCCGCCGCGACGGGGGACGCGCGGCGCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA

>NZ_CP010849|21|20|6767499-6767639|CRISPRCasFinder
GCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA	GGCCACGGGTTTCTCGCGGCACGCAGCAGGCCCGCCGCGACGGGGGACGCGCGGC
GCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010849.1|WP_044385926.1|6771989_6772655_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380064
NZ_CP010849.1|WP_044385918.1|6769180_6769375_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385928.1|6772997_6773873_+|shikimate-dehydrogenase	unknown	unknown	gnl|CDD|183586
NZ_CP010849.1|WP_044385930.1|6773885_6775691_+|sugar-phosphate-isomerase/epimerase-and-4-hydroxyphenylpyruvate-domain-containing-protein	unknown	unknown	gnl|CDD|225726
NZ_CP010849.1|WP_044385898.1|6762872_6763235_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385920.1|6769619_6769877_-|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|153418
NZ_CP010849.1|WP_044385906.1|6764284_6765118_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385908.1|6765170_6765428_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385910.1|6765459_6766002_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NZ_CP010849.1|WP_078969393.1|6770406_6771039_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP010849.1|WP_159392947.1|6767843_6768020_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385902.1|6763671_6764034_+|hypothetical-protein	unknown	unknown	gnl|CDD|373246
NZ_CP010849.1|WP_159392945.1|6764036_6764219_+|hypothetical-protein	unknown	unknown	gnl|CDD|182059
NZ_CP010849.1|WP_044385922.1|6770031_6770256_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385912.1|6766165_6766594_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385916.1|6768762_6769089_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_052808718.1|6761949_6762870_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP010849.1|WP_052808717.1|6761285_6761906_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385914.1|6768256_6768472_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP010849.1|WP_044385900.1|6763234_6763672_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP010849.1|WP_044385910.1|6765459_6766002_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.00211574
NZ_CP010849.1|WP_078969393.1|6770406_6771039_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	6.79885e-20
NZ_CP010849.1|WP_044385920.1|6769619_6769877_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|153418	cd07377, WHTH_GntR, Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators. This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.	3.07194e-20
NZ_CP010849.1|WP_044385902.1|6763671_6764034_+|hypothetical-protein	gnl|CDD|373246	pfam14722, KRAP_IP3R_bind, Ki-ras-induced actin-interacting protein-IP3R-interacting domain. This family includes the N-terminus of the actin-interacting protein sperm-specific antigen 2, or KRAP (Ki-ras-induced actin-interacting protein). This region is found to be the residues that interact with inositol 1,4,5-trisphosphate receptor (IP3R). KRAP was first localized as a membrane-bound form with extracellular regions suggesting it might be involved in the regulation of filamentous actin and signals from the outside of the cells. It has now been shown to be critical for the proper subcellular localization and function of IP3R. Inositol 1,4,5-trisphosphate receptor functions as the Ca2+ release channel on specialized endoplasmic reticulum membranes, so the subcellular localization of IP3R is crucial for its proper function.	0.00340196
NZ_CP010849.1|WP_044385928.1|6772997_6773873_+|shikimate-dehydrogenase	gnl|CDD|183586	PRK12549, PRK12549, shikimate 5-dehydrogenase; Reviewed.	1.13863e-160
NZ_CP010849.1|WP_159392945.1|6764036_6764219_+|hypothetical-protein	gnl|CDD|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	6.75224e-07
NZ_CP010849.1|WP_044385930.1|6773885_6775691_+|sugar-phosphate-isomerase/epimerase-and-4-hydroxyphenylpyruvate-domain-containing-protein	gnl|CDD|225726	COG3185, COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only].	5.73199e-84
NZ_CP010849.1|WP_052808718.1|6761949_6762870_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	3.05493e-13
NZ_CP010849.1|WP_044385926.1|6771989_6772655_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|380064	pfam17938, TetR_C_29, Tetracyclin repressor-like, C-terminal domain. This domain is found in the C-terminal region of putative TetR-family regulatory proteins.	3.63779e-58

Protein sequences

>NZ_CP010849.1|WP_044385912.1|6766165_6766594_+|hypothetical-protein
MVEDLAQWLRAQLNEDERIARAAGSGWYGYDPTEQIAFVPPEDTAHIATHSPARVLREIDAKRDLLDAHNGDCSPACRRDHTFSGSCALRWMGPVEEIDGMPWVRNEDGRQVPAPPVTTQWTLRLLALPYADRPGYREEWRP
>NZ_CP010849.1|WP_044385910.1|6765459_6766002_-|helix-turn-helix-domain-containing-protein
MNTTAAAIQANVTVATIRTWCRRGVIAAVKTAGRWVIDSASLAARIAIGAMKHPRRREATPVIDLTATYTFTHPGATRPTVVTPKIRHREIDGEHRIIIRGLAPLLASHLDAIADEGDRLHTLTVLASANIVISDTPGEYFTNLITTRDDGRLATTYTGTRALPTSVVLDLAEQLRTQLA
>NZ_CP010849.1|WP_044385908.1|6765170_6765428_-|hypothetical-protein
MSNPFDIDPRAMQEAHERRLAAMRQIKVGATYQHIHGDRDVVVTDLDEDTGYVWWRAASGPGPADSHRTLYCADFLTAYRLKPQR
>NZ_CP010849.1|WP_044385906.1|6764284_6765118_-|hypothetical-protein
MATIAKLDIRKASPPVDVDLDTLTPKARALAEAIHMSSGHQPLGVLCDTGRTKGERPNHHYVYGTGPEADRIGAEPDLRFMTNLEPLPRDAETTPEEWLEYNARQMPYDAWPIAGAKSRMEPLDERVPSADAAREDRCLTRDQALRYLGERGIVVSNDAWILLQKVGNAPQPRHYALNGRMPLWHVDDLDAYATRDYERWTISRVAEHLGYEGESATGSARKQLSRWGLHAVGRAPGRGGESLYAADQVQAAHSARPGKGRHGAIREGGRFTASSKP
>NZ_CP010849.1|WP_159392945.1|6764036_6764219_+|hypothetical-protein
MPDPIPVEPRPNDNEADTGSLIGIGEAEPEPTPGPAPAPEPSPAPTPEPSPEPPAPDETA
>NZ_CP010849.1|WP_044385902.1|6763671_6764034_+|hypothetical-protein
MNVAEWAAVVAAAGSVLGGGSWWISRATRDAAKATAAATEAAARANAAPAQQSANLAVLEATVKRVDEENGQLRGRMSRLEAMLRAFASTTDRWARQMHRAGIEPEPAHPLVDEYYRTGV
>NZ_CP010849.1|WP_044385900.1|6763234_6763672_+|hypothetical-protein
MPCRAARRLHRALGRRGVFLLILGVGKSCYGLSFLLTPPTDGGLQLLTRFGDLRQWSWLWIVCGLTTLGSAFLRIGRDKLGFLAALTPPTVWTIAYVYAVFAGGYSRGGFVALWYLTSHIGVICWAATVPEYSVPPAPRPQRGRA
>NZ_CP010849.1|WP_044385898.1|6762872_6763235_+|hypothetical-protein
MRIFGREPALVIAAVSAGLSLLVTFGFGLSAEQAGAIVAVISAVFAAATAAVTRPIAPSAFTGLVAAVAALLAAYGLELPTEQIGAINTVVLAGLALLTRGQVSPARPSAPATTEPPRAI
>NZ_CP010849.1|WP_052808718.1|6761949_6762870_+|N-acetylmuramoyl-L-alanine-amidase
MATPLSPDRFIAILRAEGVRVEEYPDWRTRERDDETGLAFGPVRMILNHHTAGRNSLGIVAKTGVPGLPPPLAHIHLAKDGVATMCSAGRANHAGPMAVNAYQSFRDEKTVHPAPSKASGTIDGNDISYGIETENLGDGKDPYPRAQYDAWVRINAAICREYGWGAESCGCHKETSVEGKVDPRGPVEGYGARGRFEFTPKQFRADVAERLKHPASWSPGATTPGKTTTKEPLVADKNDVKTLFTTDGVLSSPDGDKDKQGNRHWTAESYLRYGFLQDRETNSLVKNLAKQVAALQAAVDKLSKEA
>NZ_CP010849.1|WP_052808717.1|6761285_6761906_+|hypothetical-protein
MPDVDQYGQGIGIWQMTDAPSIPDAVKLLAAGVIPRGVMRFASASARSATLVGAQAPVDGMLTWLDDVKRLELRSEGAWVVVSVGTRAWTTVPLASGWAHNGNSQGTFQYRIVNFAGEDSIMLRGGISRDSYPSTIPGSFTLNTTTLPASARPSTLRTIVVPCSDVSSDRITMKLDITPAGQLILYGITSTAKPPWIGFNGCFASL
>NZ_CP010849.1|WP_159392947.1|6767843_6768020_+|hypothetical-protein
MTTTPFSEFMKNTKPGPQRRCIGCDTFSLRTYTEPANQEEKVICTNPACRDSPLYREQ
>NZ_CP010849.1|WP_044385914.1|6768256_6768472_-|hypothetical-protein
MATDRPVVVYPPDEEGGRRVHINGRIAGRAYSVRDIAAFMQEAGLQDWDEMDVVRSELIEWRGGGPDVWAR
>NZ_CP010849.1|WP_044385916.1|6768762_6769089_+|hypothetical-protein
MAYRPYPNVDRALSQLGRHYPGPPLVELECLRPMGDAFARLRESTRQALAAAEAAGAYVLSTRRSTENGPVVTLSPGSVSPEVASHFPAEFIEQVNRVRRPGAVSGPS
>NZ_CP010849.1|WP_044385918.1|6769180_6769375_-|hypothetical-protein
MSDFDFPDDLLELERAAWAAMQAGTLTVDQATAVQGRITAYAAEAGLDRYTVEMVLKKAVWHAG
>NZ_CP010849.1|WP_044385920.1|6769619_6769877_-|winged-helix-turn-helix-transcriptional-regulator
MGDDQRPVDPSRPVYVWQQAADWIARRIEAGELRPGARLEGERELAEQLGIAVGTVRRAVQDLRERGLVVTLPAKGTYVAERADS
>NZ_CP010849.1|WP_044385922.1|6770031_6770256_+|hypothetical-protein
MDEPRELQPGGTTRPPVVAAGVRLPPVWEAYGRYARHATQCWACRDVDQRCELGERLRRDWLDLADRAFDQLKA
>NZ_CP010849.1|WP_078969393.1|6770406_6771039_-|GntR-family-transcriptional-regulator
MPEKRARHRRIAADIRRRIAAGEWRPGDPLPSRAELAAELGVNPQTVRLAYVLLRRAGVLEGEERRAVYVAHPPVMRTLTDADADWPFFSEATDTSPRRATEELAERLDVPVGATLRHETVECLDPGGRSAMLVTTWWRGERQPHVSFTAELGVVSLGRGHAHALGLLVDALAFRVVRTRLDAQGRPLETADLILPMDRWLVRLAPTAQR
>NZ_CP010849.1|WP_044385926.1|6771989_6772655_-|TetR/AcrR-family-transcriptional-regulator
MTRVDEPARPGGRIRDAARTKAEILDVATQEFARAGYDGARVDEIAARTRTTKRMIYYYFGGKEQLFTAVLERAYGVIRQAEQQLDVDHLDPVAAIRRLAELTFDHHERHPDFIRLVSIENIHEAEHIAASEKLGRMGSPALEVIRRILAAGRESGLFTADVDAVDLHAMISSFCFFRVANRHTFGALFGRDLVDPAQREHYRTMLGDMVIAYLTAERAAD
>NZ_CP010849.1|WP_044385928.1|6772997_6773873_+|shikimate-dehydrogenase
MPKDSYLVGLIGSGIGPSLSPALHEREADRQGLRYLYRLIDIDTLGVPPEAVGDLVRAARDLGFDGLNITHPCKQLVLEHLDGLAPQAEALGAVNTVVFDGGRAIGHNTDVTGFAASFARGLPDAPLERVVQLGAGGAGAAVAHATLTLGAGRVTVVDALPGRAAALAASLERHFGEGRAAFAAPDRLAELTAAADGIVHATPTGMAAHPGLPLPAGLLHPGLWVAEVVYRPLETELLRTARALGCAVLDGGGMAAFQAVDAFRLFTGREPDGARMLADLAELAGAVTAPK
>NZ_CP010849.1|WP_044385930.1|6773885_6775691_+|sugar-phosphate-isomerase/epimerase-and-4-hydroxyphenylpyruvate-domain-containing-protein
MRTSIATVSLSGSLTEKLNAAARAGFDGVEIFENDLLASPLTPEEVRDRCADLGLTIDLYQPMRDVEALPAEEFARTLRRARHKFELMRRLGADTVLVCSSVSPLAVDDDALAAGQLARLADLAQDFGIRVAYEALAWGRHVSTYDHAWRIVEAAGHPALGTCLDSFHILSRGSDPRGIEGIPGEKIFFLQLADAPRLAMDVLQWSRHHRCFPGQGGFDVAGLVRHVLRTGYDGPLSLEVFNDVFRQSDAGATAVDAQRSLRLLQEQVGLTAPPAPVVPTGVAFAELVTPDAEPVAALLGALGFARTARHRGGKPVDLWQQGQARVLVNTGTAARREGTHLAAVGLESPDPAGAARRAEALLAPVLPRRRAPQDAPLEAVAAPDGTELFFCATGREALPDWRADFPAAGPGAPRATGVRRIDHLSLTQPWHHFDEAALFHRSVLGLRAQESVDVADPYGLLRSRAVTNADGSVRIVLTVGPAPADDTAHAQHIALATDDVVAAARRFRAAGGRLLPIPANYYDDLAARHEFADGELETYRELGILYDRDTHGGVFRHCYTHTVGRVFFELVQREGGYRGYGAQNAPVRLAAQHAVRALTGG

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP010849_2	2.4|762298|17|NZ_CP010849|CRISPRCasFinder	762298-762314	17	NZ_CP010849.1	762361-762377	0	1.0
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	NZ_CP010849.1	811497-811527	0	1.0
NZ_CP010849_13	13.1|3327644|48|NZ_CP010849|CRISPRCasFinder	3327644-3327691	48	NZ_CP010849.1	3328180-3328227	0	1.0
NZ_CP010849_14	14.1|3984738|37|NZ_CP010849|CRISPRCasFinder	3984738-3984774	37	NZ_CP010849.1	3984278-3984314	0	1.0
NZ_CP010849_14	14.2|3984818|37|NZ_CP010849|CRISPRCasFinder	3984818-3984854	37	NZ_CP010849.1	3984420-3984456	0	1.0
NZ_CP010849_15	15.1|4829372|33|NZ_CP010849|CRISPRCasFinder	4829372-4829404	33	NZ_CP010849.1	4828747-4828779	0	1.0
NZ_CP010849_18	18.1|5122375|41|NZ_CP010849|CRISPRCasFinder	5122375-5122415	41	NZ_CP010849.1	5122663-5122703	0	1.0
NZ_CP010849_19	19.1|5349381|51|NZ_CP010849|CRISPRCasFinder	5349381-5349431	51	NZ_CP010849.1	5350073-5350123	0	1.0
NZ_CP010849_21	21.1|6767542|55|NZ_CP010849|CRISPRCasFinder	6767542-6767596	55	NZ_CP010849.1	6768051-6768105	0	1.0
NZ_CP010849_2	2.4|762298|17|NZ_CP010849|CRISPRCasFinder	762298-762314	17	NZ_CP010849.1	5338954-5338970	1	0.941
NZ_CP010849_2	2.4|762298|17|NZ_CP010849|CRISPRCasFinder	762298-762314	17	NZ_CP010849.1	5265952-5265968	1	0.941
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	NZ_CP010849.1	811120-811150	1	0.968
NZ_CP010849_9	9.4|2927202|18|NZ_CP010849|CRISPRCasFinder	2927202-2927219	18	NZ_CP010849.1	6873553-6873570	1	0.944
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	337890-337908	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	1093055-1093073	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	2105152-2105170	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	2940884-2940902	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	3111224-3111242	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	4471606-4471624	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	4510556-4510574	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	6311905-6311923	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	7104308-7104326	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	637145-637163	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	816262-816280	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	2008695-2008713	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	5722634-5722652	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	5833740-5833758	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	7186849-7186867	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	7190249-7190267	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	7274793-7274811	2	0.895
NZ_CP010849_9	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	NZ_CP010849.1	1830597-1830615	9	0.526

1. spacer 2.4|762298|17|NZ_CP010849|CRISPRCasFinder matches to position: 762361-762377, mismatch: 0, identity: 1.0

ggggattcggcgggcgc	CRISPR spacer
ggggattcggcgggcgc	Protospacer
*****************

2. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to position: 811497-811527, mismatch: 0, identity: 1.0

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
gtcgtcggctcgccggggcaggccaactact	Protospacer
*******************************

3. spacer 13.1|3327644|48|NZ_CP010849|CRISPRCasFinder matches to position: 3328180-3328227, mismatch: 0, identity: 1.0

gtcggcgtcgtcggcgcggttgccgtcgggtgggaacggcctggtggg	CRISPR spacer
gtcggcgtcgtcggcgcggttgccgtcgggtgggaacggcctggtggg	Protospacer
************************************************

4. spacer 14.1|3984738|37|NZ_CP010849|CRISPRCasFinder matches to position: 3984278-3984314, mismatch: 0, identity: 1.0

gcgatcctgcgcaagaaggcggtgcaggagcagctca	CRISPR spacer
gcgatcctgcgcaagaaggcggtgcaggagcagctca	Protospacer
*************************************

5. spacer 14.2|3984818|37|NZ_CP010849|CRISPRCasFinder matches to position: 3984420-3984456, mismatch: 0, identity: 1.0

gctggagagcacgatctgcttgttggcgttgtggagg	CRISPR spacer
gctggagagcacgatctgcttgttggcgttgtggagg	Protospacer
*************************************

6. spacer 15.1|4829372|33|NZ_CP010849|CRISPRCasFinder matches to position: 4828747-4828779, mismatch: 0, identity: 1.0

ctgctgcagagcgcgctgttctcgacgtacaag	CRISPR spacer
ctgctgcagagcgcgctgttctcgacgtacaag	Protospacer
*********************************

7. spacer 18.1|5122375|41|NZ_CP010849|CRISPRCasFinder matches to position: 5122663-5122703, mismatch: 0, identity: 1.0

gtcgtcgacgaggccgccgcgtccaagctgaagctcgccgg	CRISPR spacer
gtcgtcgacgaggccgccgcgtccaagctgaagctcgccgg	Protospacer
*****************************************

8. spacer 19.1|5349381|51|NZ_CP010849|CRISPRCasFinder matches to position: 5350073-5350123, mismatch: 0, identity: 1.0

gtggtgaaggtgacgcgcgcgagggcggcgtcgcggtcggcggcggtgatc	CRISPR spacer
gtggtgaaggtgacgcgcgcgagggcggcgtcgcggtcggcggcggtgatc	Protospacer
***************************************************

9. spacer 21.1|6767542|55|NZ_CP010849|CRISPRCasFinder matches to position: 6768051-6768105, mismatch: 0, identity: 1.0

ggccacgggtttctcgcggcacgcagcaggcccgccgcgacgggggacgcgcggc	CRISPR spacer
ggccacgggtttctcgcggcacgcagcaggcccgccgcgacgggggacgcgcggc	Protospacer
*******************************************************

10. spacer 2.4|762298|17|NZ_CP010849|CRISPRCasFinder matches to position: 5338954-5338970, mismatch: 1, identity: 0.941

ggggattcggcgggcgc	CRISPR spacer
ggggatccggcgggcgc	Protospacer
******.**********

11. spacer 2.4|762298|17|NZ_CP010849|CRISPRCasFinder matches to position: 5265952-5265968, mismatch: 1, identity: 0.941

ggggattcggcgggcgc	CRISPR spacer
ggggatgcggcgggcgc	Protospacer
****** **********

12. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to position: 811120-811150, mismatch: 1, identity: 0.968

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
gtcgtccgctcgccggggcaggccaactact	Protospacer
****** ************************

13. spacer 9.4|2927202|18|NZ_CP010849|CRISPRCasFinder matches to position: 6873553-6873570, mismatch: 1, identity: 0.944

ctcccgccgggtcccggt	CRISPR spacer
ctcccggcgggtcccggt	Protospacer
****** ***********

14. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 337890-337908, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgtcgcccggccggaccg	Protospacer
***.*******.*******

15. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 1093055-1093073, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgcctcccggtcgggccg	Protospacer
***** *********.***

16. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 2105152-2105170, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccgcccggaccg	Protospacer
********** .*******

17. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 2940884-2940902, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccgcgcggaccg	Protospacer
**********  *******

18. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 3111224-3111242, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccgctcggcccg	Protospacer
********** **** ***

19. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 4471606-4471624, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccggccggccggaccg	Protospacer
****** ****.*******

20. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 4510556-4510574, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccggccggtcgggccg	Protospacer
****** ********.***

21. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 6311905-6311923, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccggccgggccg	Protospacer
***********.***.***

22. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 7104308-7104326, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccgggcggcccg	Protospacer
*********** *** ***

23. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 637145-637163, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccggtcgccccg	Protospacer
**************  ***

24. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 816262-816280, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgccgggtcggcccg	Protospacer
******** ****** ***

25. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 2008695-2008713, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgccgggtcgggccg	Protospacer
******** ******.***

26. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 5722634-5722652, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccgctcggcccg	Protospacer
********** **** ***

27. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 5833740-5833758, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccggcccgaccg	Protospacer
***********.* *****

28. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 7186849-7186867, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcacggtcggagcg	Protospacer
******* ******** **

29. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 7190249-7190267, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgccctggcggaccg	Protospacer
********* * *******

30. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 7274793-7274811, mismatch: 2, identity: 0.895

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccggacgggccg	Protospacer
*********** ***.***

31. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to position: 1830597-1830615, mismatch: 9, identity: 0.526

ccgccgcccggtcggaccg--------	CRISPR spacer
--------cggtcggacagggcggcgg	Protospacer
        ********* *        

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	305959-305981	2	0.913
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1631354-1631376	2	0.913
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	454653-454675	2	0.913
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	554062-554084	3	0.87
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	197435-197457	3	0.87
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NZ_CP030128	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence	301277-301299	3	0.87
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NC_015178	Acidiphilium multivorum AIU301 plasmid pACMV1, complete sequence	171695-171717	3	0.87
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NC_004808	Streptomyces rochei plasmid pSLA2-L DNA, complete sequence	3453-3475	3	0.87
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	2009170-2009192	3	0.87
NZ_CP010849_2	2.3|762247|23|NZ_CP010849|CRISPRCasFinder	762247-762269	23	NC_009469	Acidiphilium cryptum JF-5 plasmid pACRY03, complete sequence	79889-79911	3	0.87
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	LT635652	Aeromonas caviae plasmid 9789_1_13, strain 9789_1_13	558-587	4	0.867
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP026408	Aeromonas sp. ASNIH2 plasmid pAER-f133, complete sequence	13349-13378	4	0.867
NZ_CP010849_2	2.2|762190|29|NZ_CP010849|CRISPRCasFinder	762190-762218	29	NC_015314	Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence	49983-50011	5	0.828
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	497037-497067	5	0.839
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	239405-239435	5	0.839
NZ_CP010849_11	11.1|3219418|28|NZ_CP010849|CRISPRCasFinder	3219418-3219445	28	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	389573-389600	5	0.821
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	248203-248232	5	0.833
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NC_008757	Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence	317092-317122	6	0.806
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	136038-136068	6	0.806
NZ_CP010849_11	11.1|3219418|28|NZ_CP010849|CRISPRCasFinder	3219418-3219445	28	NZ_CP010861	Marinovum algicola DG 898 plasmid pMaD6, complete sequence	24936-24963	6	0.786
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	440666-440695	6	0.8
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	587559-587588	6	0.8
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	MN096358	Microbacterium phage LeeroyJenkins, complete genome	23711-23740	6	0.8
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	MN096357	Microbacterium phage WaterT, complete genome	22572-22601	6	0.8
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	MT818426	Microbacterium phage Lifes, complete genome	20483-20512	6	0.8
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	621000-621029	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	712723-712752	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1179075-1179104	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1207899-1207928	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	926925-926954	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	613596-613625	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	364759-364788	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP013941	Cronobacter malonaticus LMG 23826 plasmid pCMA1, complete sequence	34364-34393	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	927016-927045	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	581383-581412	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1208495-1208524	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	935077-935106	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	926783-926812	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1581263-1581292	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	532243-532272	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_023024	Cronobacter malonaticus plasmid p1, complete sequence	29009-29038	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	926738-926767	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	505474-505503	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	498352-498381	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	498352-498381	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1599604-1599633	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1454374-1454403	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1538077-1538106	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1510938-1510967	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	38054-38083	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1528352-1528381	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1533992-1534021	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1538044-1538073	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	194421-194450	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1706350-1706379	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1273701-1273730	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1261531-1261560	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1538075-1538104	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1833414-1833443	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1451840-1451869	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	530815-530844	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1973207-1973236	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1535802-1535831	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1245459-1245488	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1460652-1460681	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1492579-1492608	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1421620-1421649	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1421611-1421640	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1457382-1457411	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1636810-1636839	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_AP022320	Burkholderia sp. THE68 plasmid BTHE68_p2, complete sequence	172673-172702	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1421366-1421395	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1547282-1547311	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1636777-1636806	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1512778-1512807	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1545986-1546015	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1635571-1635600	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1533999-1534028	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1449061-1449090	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1513090-1513119	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1545986-1546015	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1445516-1445545	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1249967-1249996	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1635607-1635636	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1512778-1512807	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	1390776-1390805	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP012258	Cronobacter universalis NCTC 9529 plasmid pCUNV1, complete sequence	30009-30038	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1449707-1449736	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1511981-1512010	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1545986-1546015	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1545986-1546015	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1545986-1546015	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1635607-1635636	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1635596-1635625	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1449083-1449112	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1453401-1453430	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1434053-1434082	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1486998-1487027	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1526188-1526217	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1543301-1543330	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1635596-1635625	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1449083-1449112	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1513089-1513118	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1549803-1549832	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1636597-1636626	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1449083-1449112	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1449083-1449112	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1635607-1635636	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1545989-1546018	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1635618-1635647	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1635419-1635448	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	MH576962	Streptomyces phage Satis, complete genome	54730-54759	6	0.8
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	MK620894	Streptomyces phage Kradal, complete genome	54734-54763	6	0.8
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1975132-1975162	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	2071757-2071787	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1871173-1871203	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	2021684-2021714	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	218632-218662	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1870193-1870223	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1973036-1973066	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1973038-1973068	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1870517-1870547	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1870566-1870596	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1871153-1871183	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1975323-1975353	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1975321-1975351	7	0.774
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1975285-1975315	7	0.774
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	NZ_CP044217	Mesorhizobium sp. NIBRBAC000500504 plasmid unnamed, complete sequence	213988-214018	7	0.774
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	1091693-1091726	7	0.794
NZ_CP010849_11	11.1|3219418|28|NZ_CP010849|CRISPRCasFinder	3219418-3219445	28	NZ_CP023550	Rhodobacter sp. CZR27 plasmid unnamed2, complete sequence	95352-95379	7	0.75
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NZ_CP023713	Rhodococcus ruber strain YC-YT1 plasmid unnamed2, complete sequence	32922-32951	7	0.767
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	MK305889	Gordonia phage Mutzi, complete genome	24036-24065	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	202346-202375	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	283246-283275	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	401076-401105	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_019338	Arthrobacter sp. J3-37 plasmid pJ337-114, complete sequence	72207-72236	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP021919	Sagittula sp. P11 plasmid unnamed5, complete sequence	39220-39249	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1700361-1700390	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	901720-901749	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1419840-1419869	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	628244-628273	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	727200-727229	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	225795-225824	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	112758-112787	7	0.767
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	MN813686	Mycobacterium phage BirdsNest, complete genome	10758-10787	7	0.767
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	759758-759788	8	0.742
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	361527-361557	8	0.742
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	18784-18814	8	0.742
NZ_CP010849_2	2.2|762190|29|NZ_CP010849|CRISPRCasFinder	762190-762218	29	MK967384	Gordonia phage Sidious, complete genome	13055-13083	8	0.724
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	NZ_CP022194	Yangia pacifica strain YSBP01 plasmid unnamed4, complete sequence	75903-75933	8	0.742
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	138237-138270	8	0.765
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NZ_CP011277	Planctomyces sp. SH-PL62 plasmid pPL62-4, complete sequence	226-259	8	0.765
NZ_CP010849_15	15.1|4829372|33|NZ_CP010849|CRISPRCasFinder	4829372-4829404	33	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	2123381-2123413	8	0.758
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	MT771339	Gordonia phage Archimedes, complete genome	12733-12762	8	0.733
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NZ_CP017058	Citrobacter freundii strain SL151 plasmid unnamed1, complete sequence	49190-49219	8	0.733
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NZ_CP037902	Cupriavidus metallidurans strain BS1 plasmid p1, complete sequence	280231-280260	8	0.733
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NZ_CP026552	Citrobacter sp. SL156 plasmid unnamed3	54277-54306	8	0.733
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	MT522006	Gordonia phage BBQValindra, complete genome	14417-14446	8	0.733
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	MN583270	Pseudomonas aeruginosa strain NK546 plasmid pNK546b, complete sequence	200667-200696	8	0.733
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP024425	Paracoccus yeei strain TT13 plasmid pTT13-3, complete sequence	163098-163127	8	0.733
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_MN433457	Pseudomonas aeruginosa strain PAB546 plasmid pNK546-KPC, complete sequence	358396-358425	8	0.733
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	MF344569	Pseudomonas aeruginosa plasmid p12939-PER, complete sequence	330788-330817	8	0.733
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP035505	Kocuria indica strain CE7 plasmid pCE7, complete sequence	13166-13195	8	0.733
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_023136	Leisingera methylohalidivorans DSM 14336 plasmid unnamed, complete sequence	9350-9379	8	0.733
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	67591-67620	8	0.733
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP024423	Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence	132233-132263	9	0.71
NZ_CP010849_1	1.1|238117|31|NZ_CP010849|CRISPRCasFinder	238117-238147	31	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	225315-225345	9	0.71
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	213566-213596	9	0.71
NZ_CP010849_3	3.1|811302|31|NZ_CP010849|CRISPRCasFinder	811302-811332	31	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	152923-152953	9	0.71
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	248718-248751	9	0.735
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NC_010851	Streptomyces sp. FR1 plasmid pFRL1, complete sequence	11398-11431	9	0.735
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NZ_LN831789	Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 = NRRL B-24963) plasmid pSLE2	86559-86592	9	0.735
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	2093563-2093596	9	0.735
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1022421-1022454	9	0.735
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	MK878901	Gordonia phage HannahD, complete genome	36856-36889	9	0.735
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	MH479915	Gordonia phage GEazy, complete genome	37489-37522	9	0.735
NZ_CP010849_20	20.2|5383141|30|NZ_CP010849|CRISPRCasFinder	5383141-5383170	30	NZ_LT969519	Pseudomonas aeruginosa isolate RW109 genome assembly, plasmid: RW109 plasmid 1	18502-18531	9	0.7
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	211270-211299	9	0.7
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	529749-529778	9	0.7
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	314115-314144	9	0.7
NZ_CP010849_20	20.3|5383195|30|NZ_CP010849|CRISPRCasFinder	5383195-5383224	30	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1715364-1715393	9	0.7
NZ_CP010849_9	9.2|2927107|34|NZ_CP010849|CRISPRCasFinder	2927107-2927140	34	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	53934-53967	10	0.706
NZ_CP010849_14	14.2|3984818|37|NZ_CP010849|CRISPRCasFinder	3984818-3984854	37	JN700520	Staphylococcus phage StB12, complete genome	33166-33202	11	0.703
NZ_CP010849_14	14.1|3984738|37|NZ_CP010849|CRISPRCasFinder	3984738-3984774	37	NZ_CP053906	Hymenobacter sp. BRD67 plasmid unnamed2, complete sequence	53412-53448	12	0.676

1. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 2, identity: 0.913

acggcggccggtgcggcggaggt	CRISPR spacer
gcggcggccggggcggcggaggt	Protospacer
.********** ***********

2. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 2, identity: 0.913

acggcggccggtgcggcggaggt	CRISPR spacer
acggcggcgggtgcggcgaaggt	Protospacer
******** *********.****

3. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 2, identity: 0.913

acggcggccggtgcggcggaggt	CRISPR spacer
acggcggccggtgcggcggccgt	Protospacer
*******************  **

4. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 3, identity: 0.87

acggcggccggtgcggcggaggt	CRISPR spacer
cgagcggccggtgcggcggaggt	Protospacer
  .********************

5. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.87

acggcggccggtgcggcggaggt	CRISPR spacer
gcggcggccggtgcggcgcaggg	Protospacer
.***************** *** 

6. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NZ_CP030128 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.87

acggcggccggtgcggcggaggt	CRISPR spacer
acggcggccggtgcggcggcaat	Protospacer
******************* ..*

7. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NC_015178 (Acidiphilium multivorum AIU301 plasmid pACMV1, complete sequence) position: , mismatch: 3, identity: 0.87

acggcggccggtgcggcggaggt	CRISPR spacer
gtggcggccggtgcggcggtggt	Protospacer
..***************** ***

8. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NC_004808 (Streptomyces rochei plasmid pSLA2-L DNA, complete sequence) position: , mismatch: 3, identity: 0.87

acggcggccggtgcggcggaggt	CRISPR spacer
tcggcggccggtgcggcggtggg	Protospacer
 ****************** ** 

9. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 3, identity: 0.87

acggcggccggtgcggcggaggt	CRISPR spacer
acggcggcgggtgcggcggagag	Protospacer
******** ************. 

10. spacer 2.3|762247|23|NZ_CP010849|CRISPRCasFinder matches to NC_009469 (Acidiphilium cryptum JF-5 plasmid pACRY03, complete sequence) position: , mismatch: 3, identity: 0.87

acggcggccggtgcggcggaggt	CRISPR spacer
gtggcggccggtgcggcggtggt	Protospacer
..***************** ***

11. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to LT635652 (Aeromonas caviae plasmid 9789_1_13, strain 9789_1_13) position: , mismatch: 4, identity: 0.867

ctcctgggcctgcgccgaggcggc--gttcag	CRISPR spacer
ctccttggcctgcgccgtggcggcgagttc--	Protospacer
***** *********** ******  ****  

12. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP026408 (Aeromonas sp. ASNIH2 plasmid pAER-f133, complete sequence) position: , mismatch: 4, identity: 0.867

ctcctgggcctgcgccgaggcggc--gttcag	CRISPR spacer
ctccttggcctgcgccgtggcggcgagttc--	Protospacer
***** *********** ******  ****  

13. spacer 2.2|762190|29|NZ_CP010849|CRISPRCasFinder matches to NC_015314 (Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence) position: , mismatch: 5, identity: 0.828

gtcggggcggacccggcgggttccacggc	CRISPR spacer
ggctgggcggcgccggcgggttccacgac	Protospacer
* * ******  ***************.*

14. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 5, identity: 0.839

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
accctcggctcgccgggccaggccaactacg	Protospacer
..* ************* ************ 

15. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 5, identity: 0.839

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
gttctcggctcgccggggcaggcgaattacg	Protospacer
**. ******************* **.*** 

16. spacer 11.1|3219418|28|NZ_CP010849|CRISPRCasFinder matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 5, identity: 0.821

gggtgccgcgtcacggcggcccccgggc	CRISPR spacer
cgctgccgcgccacggctgcccccggcc	Protospacer
 * *******.****** ******** *

17. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 5, identity: 0.833

ggcctccga--ctcggtggcggtggtggtgcg	CRISPR spacer
--cccctgacgctcggtggcggtggcggtgcg	Protospacer
  **.*.**  **************.******

18. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NC_008757 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence) position: , mismatch: 6, identity: 0.806

aggggcagggcgggcgcccgggggcagggtg	CRISPR spacer
gggggcagggcgggcgccggcgggcgcgggg	Protospacer
.***************** * ****. ** *

19. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 6, identity: 0.806

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
acgctcggctcggcggggcaggccaactacg	Protospacer
..  ******** ***************** 

20. spacer 11.1|3219418|28|NZ_CP010849|CRISPRCasFinder matches to NZ_CP010861 (Marinovum algicola DG 898 plasmid pMaD6, complete sequence) position: , mismatch: 6, identity: 0.786

gggtgccgcgtcacggcggcccccgggc	CRISPR spacer
tagagccgcgtcacggcgggccgcgggg	Protospacer
 .* *************** ** **** 

21. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 6, identity: 0.8

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
cgcggccgacccggaggcggtggtggtgcc	Protospacer
 **  *****.*** ************** 

22. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 6, identity: 0.8

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
cgcggccgacccggaggcggtggtggtgcc	Protospacer
 **  *****.*** ************** 

23. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to MN096358 (Microbacterium phage LeeroyJenkins, complete genome) position: , mismatch: 6, identity: 0.8

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
gatttgcgactcggtggcggcagtggtgcg	Protospacer
*...* **************..********

24. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to MN096357 (Microbacterium phage WaterT, complete genome) position: , mismatch: 6, identity: 0.8

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
gatttgcgactcggtggcggcagtggtgcg	Protospacer
*...* **************..********

25. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to MT818426 (Microbacterium phage Lifes, complete genome) position: , mismatch: 6, identity: 0.8

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
gatttgcgactcggtggcggcagtggtgcg	Protospacer
*...* **************..********

26. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 6, identity: 0.8

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
gccgtacgactcggtggcggaggtggcgca	Protospacer
* * * ************** *****.**.

27. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cccgtgggcctgggccgaggcggcgatcgc	Protospacer
*.* ******** ************ **. 

28. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

29. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

30. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cgactgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

31. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

32. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

33. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP013941 (Cronobacter malonaticus LMG 23826 plasmid pCMA1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cgccgtggcctgcgccgcgtcggcgttcat	Protospacer
* **  *********** * ********* 

34. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cgactgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

35. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

36. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

37. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

38. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

39. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

40. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

41. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_023024 (Cronobacter malonaticus plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cgccgtggcctgcgccgcgtcggcgttcat	Protospacer
* **  *********** * ********* 

42. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

43. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

44. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

45. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

46. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

47. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

48. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

49. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

50. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

51. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

52. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

53. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cgactgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

54. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgag---gcggcgttcag	CRISPR spacer
cgccagggcctgcgccgaggccgcggcgtc---	Protospacer
* ** **************   *******.   

55. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

56. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

57. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

58. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

59. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

60. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

61. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

62. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

63. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

64. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

65. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

66. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

67. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

68. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

69. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

70. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

71. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_AP022320 (Burkholderia sp. THE68 plasmid BTHE68_p2, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ctcggccgcctgcgcccacgcggcgttcag	Protospacer
***    ********* * ***********

72. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

73. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

74. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

75. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

76. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

77. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

78. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

79. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

80. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

81. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

82. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

83. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

84. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

85. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

86. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgcccgggcggcgtgctg	Protospacer
*  ************* .******** * *

87. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP012258 (Cronobacter universalis NCTC 9529 plasmid pCUNV1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cgccgtggcctgcgccgcgtcggcgttcat	Protospacer
* **  *********** * ********* 

88. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

89. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

90. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

91. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

92. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

93. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

94. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

95. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

96. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

97. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

98. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

99. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

100. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

101. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

102. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

103. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

104. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

105. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

106. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

107. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

108. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

109. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

110. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

111. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgggcctgcgccccggcggcgtgctg	Protospacer
*  *************  ******** * *

112. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to MH576962 (Streptomyces phage Satis, complete genome) position: , mismatch: 6, identity: 0.8

ctcctgggc---ctgcgccgaggcggcgttcag	CRISPR spacer
---gggggcctgctgcgccgaggaggcgttcag	Protospacer
     ****   *********** *********

113. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to MK620894 (Streptomyces phage Kradal, complete genome) position: , mismatch: 6, identity: 0.8

ctcctgggc---ctgcgccgaggcggcgttcag	CRISPR spacer
---gggggcctgctgcgccgaggaggcgttcag	Protospacer
     ****   *********** *********

114. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

115. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

116. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

117. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

118. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg	CRISPR spacer
cggggcagggcgggcttccggggggcccgtg	Protospacer
 ************** .*******    ***

119. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

120. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

121. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

122. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

123. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

124. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

125. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

126. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

127. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

aggggcagggcgggcgcccgggggcagggtg-	CRISPR spacer
gggggcagggcaggcgcccggtggt-gactgc	Protospacer
.**********.********* **. *. ** 

128. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP044217 (Mesorhizobium sp. NIBRBAC000500504 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
gtgatcggctcgccggggcagggcaagtcgc	Protospacer
** .****************** *** *  .

129. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

-actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
caatgc-cgatgtcggctgccgcaagggcgggggc	Protospacer
 * * * **. ************ .**********

130. spacer 11.1|3219418|28|NZ_CP010849|CRISPRCasFinder matches to NZ_CP023550 (Rhodobacter sp. CZR27 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.75

gggtgccgcgtcacggcggcccccgggc	CRISPR spacer
gggtgcagcgtcacggcggccaggagct	Protospacer
****** **************   .* .

131. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP023713 (Rhodococcus ruber strain YC-YT1 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

ggcctc----cgactcggtggcggtggtggtgcg	CRISPR spacer
----tcggggtggctcggtggcggtggtggagcg	Protospacer
    **    .*.***************** ***

132. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to MK305889 (Gordonia phage Mutzi, complete genome) position: , mismatch: 7, identity: 0.767

ggcctcc-----gactcggtggcggtggtggtgcg	CRISPR spacer
-----ccgggtggactcggcggcggtggcggtgcg	Protospacer
     **     *******.********.******

133. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ggtttgggcgtgcgccgaggcggcgatcat	Protospacer
  ..***** *************** *** 

134. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cggctgcgcctgcgccgaggcggcgcagaa	Protospacer
*  *** ******************.  *.

135. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
tccgtgggcctgggccgaggcggcgatcgc	Protospacer
..* ******** ************ **. 

136. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_019338 (Arthrobacter sp. J3-37 plasmid pJ337-114, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ggcaatggcctgcgccgcgtcggcgttcag	Protospacer
  *   *********** * **********

137. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP021919 (Sagittula sp. P11 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgg-----gcctgcgccgaggcggcgttcag	CRISPR spacer
-----ggacatcgcctgcgccgaggcggcgatccg	Protospacer
     **     ****************** ** *

138. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ttcggcggcgtgcgccggggcggcgttcac	Protospacer
.**   *** *******.*********** 

139. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
tgcctcggcctgcgccaaggcggcgcgcaa	Protospacer
. *** **********.********. **.

140. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
tgcctcggcctgcgccaaggcggcgcgcaa	Protospacer
. *** **********.********. **.

141. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
tgcctcggcctgcgccaaggcggcgcgcaa	Protospacer
. *** **********.********. **.

142. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
tgcctcggcctgcgccaaggcggcgcgcaa	Protospacer
. *** **********.********. **.

143. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
tgcctcggcctgcgccaaggcggcgcgcaa	Protospacer
. *** **********.********. **.

144. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ttcggcggcgtgcgccggggcggcgttcac	Protospacer
.**   *** *******.*********** 

145. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to MN813686 (Mycobacterium phage BirdsNest, complete genome) position: , mismatch: 7, identity: 0.767

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
cacctcggcccgcgccgaggcggcgaccgc	Protospacer
* *** ****.************** .*. 

146. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 8, identity: 0.742

aggggcagggcgggcgcccgggggcagggtg	CRISPR spacer
aggggcgcggcgggcgcccggggtgcccctg	Protospacer
******. ***************      **

147. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 8, identity: 0.742

aggggcagggcgggcgcccgggggcagggtg	CRISPR spacer
aggggcgcggcgggcgcccggggtgcccctg	Protospacer
******. ***************      **

148. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 8, identity: 0.742

aggggcagggcgggcgcccgggggcagggtg	CRISPR spacer
aggggcgcggcgggcgcccggggtgcccctg	Protospacer
******. ***************      **

149. spacer 2.2|762190|29|NZ_CP010849|CRISPRCasFinder matches to MK967384 (Gordonia phage Sidious, complete genome) position: , mismatch: 8, identity: 0.724

gtcggggcggacccggcgggttccacggc	CRISPR spacer
gtcggggcggccccggcgggtggtggcga	Protospacer
********** **********  ..  * 

150. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022194 (Yangia pacifica strain YSBP01 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.742

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
gagggcgacgcgccggggcaggccaactgga	Protospacer
*  * **.* ******************.  

151. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 8, identity: 0.765

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
gcaagccggggtcggctgccgccgtgccggggtc	Protospacer
.*    ****************** * ***** *

152. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NZ_CP011277 (Planctomyces sp. SH-PL62 plasmid pPL62-4, complete sequence) position: , mismatch: 8, identity: 0.765

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
gctccccgggggcggctgccgccggaaggcggac	Protospacer
.**** ***** *************.. * **.*

153. spacer 15.1|4829372|33|NZ_CP010849|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

ctgctgcagagcgcgctgttctcgacgtacaag	CRISPR spacer
ccgctggagagcgcgctgttctcgactgccgct	Protospacer
*.**** *******************   *.  

154. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to MT771339 (Gordonia phage Archimedes, complete genome) position: , mismatch: 8, identity: 0.733

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
cttgtccgactcggtgccggtggtagtggt	Protospacer
  . ************ *******.***  

155. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP017058 (Citrobacter freundii strain SL151 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
gtttaccgactcgatggcgttggtggtgta	Protospacer
* .. ********.***** ********..

156. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP037902 (Cupriavidus metallidurans strain BS1 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
gttgaccgactcgatggcgttggtggtgta	Protospacer
* .  ********.***** ********..

157. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP026552 (Citrobacter sp. SL156 plasmid unnamed3) position: , mismatch: 8, identity: 0.733

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
gtttaccgactcgatggcgttggtggtgta	Protospacer
* .. ********.***** ********..

158. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to MT522006 (Gordonia phage BBQValindra, complete genome) position: , mismatch: 8, identity: 0.733

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
catcgccgactccggggcggtggtggtggc	Protospacer
 ..* ******* * *************  

159. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to MN583270 (Pseudomonas aeruginosa strain NK546 plasmid pNK546b, complete sequence) position: , mismatch: 8, identity: 0.733

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
gctgccggcctgcgccgaggcggcctgcag	Protospacer
 .. . ****************** * ***

160. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP024425 (Paracoccus yeei strain TT13 plasmid pTT13-3, complete sequence) position: , mismatch: 8, identity: 0.733

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ctcctgggcctgagccgagacggcacaggc	Protospacer
************ ******.****..  . 

161. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_MN433457 (Pseudomonas aeruginosa strain PAB546 plasmid pNK546-KPC, complete sequence) position: , mismatch: 8, identity: 0.733

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
gctgccggcctgcgccgaggcggcctgcag	Protospacer
 .. . ****************** * ***

162. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to MF344569 (Pseudomonas aeruginosa plasmid p12939-PER, complete sequence) position: , mismatch: 8, identity: 0.733

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
gctgccggcctgcgccgaggcggcctgcag	Protospacer
 .. . ****************** * ***

163. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP035505 (Kocuria indica strain CE7 plasmid pCE7, complete sequence) position: , mismatch: 8, identity: 0.733

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
gaactgcgcctgcaccgaggcggcgtcggg	Protospacer
   *** ******.************. .*

164. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_023136 (Leisingera methylohalidivorans DSM 14336 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
gttcgacagctgcgccgaggccgcgttcag	Protospacer
 *.* . . ************ ********

165. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

ctcctgggcctgcgccgag---gcggcgttcag	CRISPR spacer
ggcctgggcctgcgccgaggacgcggggcc---	Protospacer
  *****************   **** *..   

166. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP024423 (Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence) position: , mismatch: 9, identity: 0.71

aggggcagggcgggcgcccgggggcagggtg	CRISPR spacer
gccgctgacgcgggcgcccggggtcagggtg	Protospacer
.  * ... ************** *******

167. spacer 1.1|238117|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

aggggcagggcgggcgcccgggggcagggtg	CRISPR spacer
cggggcagggcgggcggccggggctcgcacc	Protospacer
 *************** ****** . * .. 

168. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.71

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
atcgtcggcgcgccggtgcaggccgcggaag	Protospacer
.******** ****** *******.   *  

169. spacer 3.1|811302|31|NZ_CP010849|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 9, identity: 0.71

gtcgtcggctcgccggggcaggccaactact	CRISPR spacer
ttcgtcggcgcgccggtgcaggccgcggaag	Protospacer
 ******** ****** *******.   *  

170. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 9, identity: 0.735

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
ggcggacggggtccgctgccgacggggcggggcc	Protospacer
. .  .******* ******* ********** *

171. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NC_010851 (Streptomyces sp. FR1 plasmid pFRL1, complete sequence) position: , mismatch: 9, identity: 0.735

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
gcgagaccgggtcggcggccgccgtggcggggcc	Protospacer
.*   .* ******** ******* ******* *

172. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NZ_LN831789 (Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 = NRRL B-24963) plasmid pSLE2) position: , mismatch: 9, identity: 0.735

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
gcggagtcgggtcggcggccgccgtggcggggcc	Protospacer
.*   *. ******** ******* ******* *

173. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 9, identity: 0.735

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
gcacgatgggctcggctgccgccggtgcgggcac	Protospacer
.* * ..*** ************** ***** .*

174. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
gcacgatgggctcggctgccgccggtgcgggcac	Protospacer
.* * ..*** ************** ***** .*

175. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to MK878901 (Gordonia phage HannahD, complete genome) position: , mismatch: 9, identity: 0.735

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
cggcagtgccgtcggcggccgccggggcgggtgc	Protospacer
   * *.*  ****** ************** **

176. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to MH479915 (Gordonia phage GEazy, complete genome) position: , mismatch: 9, identity: 0.735

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
cggcagtgccgtcggcggccgccggggcgggtgc	Protospacer
   * *.*  ****** ************** **

177. spacer 20.2|5383141|30|NZ_CP010849|CRISPRCasFinder matches to NZ_LT969519 (Pseudomonas aeruginosa isolate RW109 genome assembly, plasmid: RW109 plasmid 1) position: , mismatch: 9, identity: 0.7

ggcctccgactcggtggcggtggtggtgcg	CRISPR spacer
cctgctcgagtcggtggcgctggtggtgct	Protospacer
  . ..*** ********* ********* 

178. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 9, identity: 0.7

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
gaactgggcctgcgccggggcggcgaaggc	Protospacer
   **************.*******   . 

179. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 9, identity: 0.7

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ctcccgggccttcgccgaggcggtcgctgc	Protospacer
****.****** ***********.  ... 

180. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 9, identity: 0.7

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ttcctgggcctgcgccggggcgatgccgtt	Protospacer
.****************.****..*..   

181. spacer 20.3|5383195|30|NZ_CP010849|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 9, identity: 0.7

ctcctgggcctgcgccgaggcggcgttcag	CRISPR spacer
ggtgcgggcctgcgccgagccggccttccc	Protospacer
  . .************** **** ***  

182. spacer 9.2|2927107|34|NZ_CP010849|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.706

actccgcggggtcggctgccgccggggcgggggc	CRISPR spacer
gatttctcgagtcggccgccgcgggggcgggggc	Protospacer
. *.. . *.******.***** ***********

183. spacer 14.2|3984818|37|NZ_CP010849|CRISPRCasFinder matches to JN700520 (Staphylococcus phage StB12, complete genome) position: , mismatch: 11, identity: 0.703

gctggagagcacgatctgcttgttggcgttgtggagg	CRISPR spacer
ctttagtagcactatcttcttgttggcgttgtgtggt	Protospacer
 .* .. ***** **** *************** .* 

184. spacer 14.1|3984738|37|NZ_CP010849|CRISPRCasFinder matches to NZ_CP053906 (Hymenobacter sp. BRD67 plasmid unnamed2, complete sequence) position: , mismatch: 12, identity: 0.676

gcgatcctgcgcaagaaggcggtgcaggagcagctca	CRISPR spacer
tcccagctgcgccagcaggcggtgcaggagcaagcgc	Protospacer
 *    ****** ** ****************. .  

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	29167 : 104722	48	Gordonia_phage(40.0%)	protease,integrase,transposase	attL 29012:29071|attR 63046:63156
DBSCAN-SWA_2	5706444 : 5756901	42	Planktothrix_phage(40.0%)	protease,tRNA	NA
DBSCAN-SWA_3	6129052 : 6153047	20	Bacillus_phage(25.0%)	plate,protease,tail	NA
DBSCAN-SWA_4	6740493 : 6748843	10	Streptomyces_phage(42.86%)	terminase,capsid,portal	NA
DBSCAN-SWA_5	6753001 : 6763672	8	Streptomyces_phage(100.0%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP010849|29167:104722|DBSCAN-SWA
CATGATCGATGAACATGCGGACGCTGGCTGGGAACGAGAACTCGATGACCTTTTTCTCTGCATCGGTCACCGCTTTGGCCGTGCTGACCTGCGGCGCCGGATGCGGGACTATGTGCGGGGCCTGCTCGCCCCCGTCGGCCGCAAGAACGGCTGGCAGTTGGCGGAGTTTGCCGGGCACCGCACGCCCGACGGCCTCCAGCGGCTGCTGAACGGAGCGACCTGGGACGCTGACGACGTCCGCGACGACCTGCAGTCGTACGTCGCCAAGCACCTCGGCGACGACAACGGGGTACTCGTCATCGACGACACCGGCTTCCTCAAGAAGGGCACCACCTCGGCTGGGGTGCAGCGCCAGTACTCCGGCACCGCCGGCCGCACAGAGAACTGCCAGATCGGTGTCTTCGCCGCCTACACCTCCGCCGCCGGCCGCGCGTTGGTGGACCGGGAACTGTATCTGCCCAAGTCCTGGACGGATGACCGTGAGCGCTGCCGGGCGGCGAAGGTCCCCGACGAGCGCGGCTTCGCCACCAAGGGAGAGCTGGCCAAGCGCCTCGTACTGCGCGCCCTGGCTTCCGGTCTTCCCCTCGCCTGGGTGGCCGCGGACGCCGCCTATGGGCAGGAGGGGCGTTTCCGCCGCATGCTGGAGCAGTCCGGCCTTGGCTACGTGCTCGCGGTGCCCAAGTCCCAGCAGGTCTTCGGCCCACGGATCGACCACCTCTTCGCTCAGGCTCCCGTGGAGGCATGGGAGCCGATCTCGTGCGGCAACGGGGCCAAGGGGCCCCGGCTCTACCACTGGGCGGCACTGGAACTGCCCACGGTGGCCGAGTTCGACTACCAGGGCGATGTCCCGGTCCGTCGGCGGTGGGCGCTGGCCCGTCGCAGCTTGAGCAGGCCAGAGGAGATCGCCTACTTCCTCGCCTACGCACCACCCGAGAGTGCGGTGGCCGACCTGGTGCGGGTCGCCGGGATGCGCTGGCAGATCGAGGAGTGCTTCCAGGCCGCGAAGAACGAGTGTGGCCTGGACCAGTACGAGGTCCGTCGTTACGTCGGCTGGTATCGGCACATCACCCTGGCGATGCTCGCTCATGCCTATCTGGCGGTCATGGCGGCCGACGCGGCGGCAAAAGGGGATGCAGAAACGCTTTTGGCCCCTTGGCTCCGCTCACCGTGGCAGAAGTCCGGCGGCTGCTGGCGCCTCGCCTCGCCGGGCACCGCCGAGGTGGCCGGTCGCTTCGCGCGCACCTGCTGAGCTGGTCACGCTGGCGCCGCAGACGCCAGGTCGTCGCCCGCCACTGCCACTACCGGCGACGACTCCACTCGTTGGAGGGGCGGTCAGGCAAGACCGCCCCTGGCACACCACTAGCCCACTACACTCCGGACGACGCCTCTGACCAGGCCAGATAGCGAAACGCTGCTGGAGTACTAGCCCGAGACGGTAAGCCGTCGACCTGTGCACAGTCCGCCGCATGAACATGAATACGAACCCGCTCCACGGAGACCCCTGCCCGCTGTGCGACCGCCCGCTCACTCTGCGCACGACCGTCGTCGTCCGCTCGAACGTGCCGTACCCCACCCGGACCGACTCCCTGCCCCACTGCACCGTCTGTGCCAACGACCTGCCCAACCGGCAGAGGTGGTACGACCTGATGAACGACCGCTACGGCCTCTGACCCGGACCGTGCGAATGCTGCGCCCGGCCTCATCAGCACCACCCATCACGAAATTCGTCCCGAGCCGACTTCAACGCCATCCAACGCGCATCAACGCACCACTTTCCCGACCGCCTACCACCGCTGAGCGCACCGCGTCACCGACGCCCTTCCACACGAACAGCCATCACCGCCCCCGGTCACCGGCCGGGGGCTTCGTGCGTCCTGGAGGAGTTCGCCGTGCCCACCTACGAGGCCCTGCCGCGCTTCACCGCCTCGCCCCCGAACAGCGTCGCCGCTTCCGCCAGGCCGTCAACGCGTTCGTCGACGGCCTGCGCGCCCGTCGAGAACGGAGGGCAGGGGGCGTCAGCCGCTGGCGGGCTCGGCGCCCGCACCGAAGCGCGGGACGTCCGTGCCCGCAACGTCCGACCGGAGAGCTGGTACCGGGCACGTATTGGAAAAGGGCTGTATTCCTGCGCTCGACCGTAGCCCCTCACGCCGTCTTGTCTTGCAGTGTCTGAGTGAGTCACTCCTCGATGCGCCGTGTGTGCTGGGCGCGTAGAGCCGGGAGTCGAGTTCTTGGCCGAGCGCCGAGCGCCGAGCGGCGGGCCTGACCGATGCGGACGTGCACCCGGCAAGGTCCGGGTTGATCGTGTCAGGGAGTCGAGGTGCCGGGCCGGCGCGGCCGACCCTGGTCTGGGAACGTGGGCGAGCCTGCCACCAGATCGGATGATCTTAGGCAAATCACCTTGCGTATCTGATCGGGTACGTAATGTGCTTGCGCTGGGGTCGAAGGTCGGCCCCGCGAAGGGACGGCACATCATGGCGACACAGGTCTCCACCGACATCGCAGCCGTGCGCAACAGCGTCTGGGTCCGCTGGCTGCCGAACGCGCTGCCTGCCGCCGGCTACATCACCTTGAAGAACTCCGGCGACAAGGACCTCAAGGTAACCAAGATCAGCAGCCCCGACTACCAGAAGATCACGGTCTACCAGACCGTTGTCGACTCCGAGAGCTCAAAGATGGTCAAGGTCGACGACTTCACCATCCCCGCCAAAGGCGAGTTCGCGTTGGTCCCGGGCCAGTTCCACCTGATGCTCGAAAAGCCGACCCATCTGATCACCCCGGCGACAACGCCCGCGTCATGTTTTTCCTCGACCTCGACCCCCGGCAGGTCTTCAAGGTCAGGATGCCCGTCCGTACCTCGCCCGAGCTGTACTGAGCCCGCCCACGCCACCAGGAGTCCCGGACATGACCACGTACCACCTCGACCTCGGCGACAACCAGACGGAAGTACTCGCCTCCGTCACCAAACTCACCATCACCCACACCGAACTCGACATCGACGCCTTCCTGGCCGCCGACGCCAACGCCCCCGTGCCCCTCTGGGGCGACGTGGTCCTCACCCGCGGCAACGACCGCCACCCCGCCACCACCGCCTGGGTCGAAGACGTCGAGAACACCAGCACCCACCAGGACGTCGTTCTCATCGCCGGCGACCCCGCCGACCCGAAGGCCCGCCGCATCCGCCTCACCGACGCCTGGGCCAGCGCCAGCTACCACCTGGACGAGGACGACGACCCCGACGCCTTCGCCATCGCCTTCACCGACATCACCGTCGAGAAGTAACCCCGCCTCCCGAACGACACAGCTCGTCCGGTCCGGAACGCTGATGCCTCAGGACCGGACGACCACATCTGGGCCCTGCCCATCGGGCCCTCTCCTGCGGCCTCAGAACCACCGTCCTCGGATCCCTGAGTGCAGCCCGTTCACCGCCATCCCGGCCACCAGGGCAGGAGGATCGACTCGTCGTTGAGTCCGGGCTCGCCTTACCGGGATGTCAGATAGGCGTTCCAGTCGCGGGCGGCGCGGCGGGTCCAGTGCAGGGCGGAGGTGATGCTGATGCCGAGGAGGTCGCTGAGGACGGGGGCGGGCAGGTCGGTGGCCAGGGTGAGCAGGGCGGTGTTGCGGCTGGGGTGGGCGGGCATCTGGTGGCGGCGGAGTTTGGCCGCGAGGGCGGCAGGGGAGCGGTGGGTGCCGGGGGCGTAGCCGGGGACGATCCAGGTGGCGGGTGGGGTGGTGCGGCCGATGGCGGATTCTTGGTGAGCGTGGTCGGCTTGCCGGCGTAGCAGACGGTGGACGGCCGGAGGCAGATCGGTGGGGTGGTCGCCGAGGATCAGCACGGGCTGGTCGCCGTCGTGAAGACGGTCGCTGGTCAGTTCGGTGATCTTGGAGACCGGCATGCCGTACAGCAGCATCAGGGCTTTTGCCGCCCGCACGTCCAGGGGCAGCGTGTCGTCGTGGAGGCAGCGTTGCAGGTGGGCCCAGTGTTCGGTGTCGCTGAACCAGGTCGGGGCCTCGCCTCGGGGCCGGGGGCGGACATCGTGGAGGCCGGTCAGGCGGCGTTGGTGGGCCCAGCGCAGGAAGGGGCGGACGTGGCGGCGTTCGAGCGGGCCGGTCAGCCACAGGTCGACCTGGTGTTGGGTGAGGTCGGCCAGGGCCGTGTGGTGTTCATCCAGCCAGAGGAGGAAGGCGCCGGCGCAGCGGATGGTGTTGCGGGCGCGGGTGGCGCTGGCGGAGGTGAAGCGGCGGCGTGCGGCGCGGCGGCGGGCCTGGCGCAGGACGGACCATTGGGCGTAGGTGCGCAGGAGGTTGCGGTGCTGGGGCGGCAGGGTGGCGAGGGTGCGTTCGAGCCAGGGCTGGAGGGCGCGTAATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGCATAACTTCGTATAGCATACATTATACGAAGTTATACGAGGTGCGTGGCGGGGCGGGAGGATGCCGAGATGGACGAGGGTGGCACGCAGGTGCGCCTGGCCGTGTCCGGGGCCGAGGGCGTCAAGGGCTTCATGGGTGACGGGAGCGCCGGAGGCGAGGAGGTTGCGCAGCAGGGCCGCTCCGCCGTGGGGTTTGTCCAGCCACACCAGGGCCGAGTAGGCGCGCGGTACGCGCAGTAGGGCCTGGTTCAGCGGCTCCAGAGCGGCGGGGACGGTGCCGTCAGGCCCGGTGAACTCGATGGTGAGACGGCGTCGCAGCACGCAGCGGGAACAGCAAGGACCGCGGTCGGTCTCCCGGCCGCTGCCGCAGATCAGGCACAGGTAAGGGTTGGCGGCGCCCGAGCACACACCGCATACCGGGCTGCCGTGATCATCGGTGCCGATCAGCGGCCGGGTACGGCCGCAGCTCGTACAGGGTCTGGGGTGGGAACGGATGTAGCGATAGCAGGCAGGGCACACGCCGCCCATCGGCCAGCGGGCCTGGTACCGACGGTCCGCTCCACAGCGTGCGCACCCCGCGGTGGCCACGGTTCGGCAGGCCCCGCACCGTGGACTGCCGGCGCGCACCCCCCGGCACGGCCGCTCACGGCCACAGCCGACACAGACGGCCAGCGGCCCCTGCCAGCAGCCGCGGCACAGATCCGGCCGGCCGTCACGGGCCCGGACATAGACGGGCCGCACCCGGCCACAGCGGCCACAGGGCTGGCGGGCGCGCCGTTTCTCCTGGCAGGGCGAGCACAGCGCCCGTCCGTCGGGCAGGCGGGCGGCCACGGCCCGGGTGTGGCCGCACCGCGCACAGGGCTCCGGCGGCGGGGCGCCGCACCGGCCGCACAGCCCGCTTCCGTCGGGCAGACGGCGCCGGACCCGTGCCCGGCGCCCGCAACTGGAACAGGGCTCGTGCCGGGCCGGGTCGGCAGCGTAACAACTCCCGCACACCGGCCCGCGGGCGTCGATGGCTGCCACGACGCCCTCACATCCGCAACGCGTACACGGGCGCTTGCGGTCTTGTGCGCCGCAGGAGCCGCACACCCTTCCCTCGGCTCGTTGTTCGGGCAGCGGGCGGAGCCGGCCGCAGCGCGCGCACCCCGGGACCTGCACCGGGTGCCCGGCCTTCTTCAGGTATTCAAGGAGGCGCAGCAGCGAGGGCGGGATGTCCGCGTTGCCGGCGGTCAGGGCGTCGGGGTGCCGGCGAAGGTGGGCGTCGAGGCGGTGCAGCCCGGCGGATGGTGCTGCGGCGTACCGGCGCCGGTACCGCCCCTGCCGCCCCTGCCGTCGGCGGCGGTCTTGCGGACCTGGGTGTTGGTCACCCTCACCTCGACCAGATCGTTCGGGGTGCAGCCGAGGATGTCGCACAAGGCGGCGAGCGTGTCCATCGACAGCCGCTGGGGTGGATGGGTCACCAGGCGGTAGACCTGCTCACGGGAGAGGTCGATGCCCCGCTCGGCCAGCAGCGGCATCAGTTCCGTGGTCTGGAACATGCCCTGCTCGGCCATCCGTAGCCGCAGATTCCACACGATGCCCATCTTCTTGTTCACGAGGTTGGCTCCCACAGCTCCGTGTGACGCGCCTGCAGAGAACGGTTCAGCAGGCGGTTGCGGTACTCCAGCGACACCCCGGTATACACCGCTGTCGTCGACCCGTACCGGTGACCGACCTGGTCCTGCACGAACCGCTCCGGATACCCGAACTCGATCAGATGGGTGATGTAGGAGTGCCGCAGGCAGTGCAGGTCCAACTCCTCGTCCAGACCCGCCACTGCCCGCACATGCGCGAACACCTCGTCCATGCGCCTGCACGACATCCGCCCCCGCCGCTCGGTCACCCACCACGCCGGATGCTCCCCCGGCGAGAACCGCGGACGCAGCTCACACTCCCAGTGATCCAGCACCGGAACCGCCCAGTCCATCTCCGGCACCAGCAACACCGTGCGCCGCTTGGGCGGACCGCCCCGCGAGGACTTCCCCCACCGCACCTGCGCCACCCCGAACCGGCCCAAGGCCGGCATCTGGGGATTGCGCCGCCAGTCCACCCGGTCCATCCCCCACGCCTCGCGGCGCCGCAGCCCGAAGGCATAGAAGGTCTTCAGCAGCGCGGCGTCCCGCTGGGCCGCCAACGCGCCCTTGCGGCGCCGGGCCCGGATCTCCTCGGCCAGACCGTCCGCCGCATCGAACAGGACCTGGACCTCGTCGTAGGTGAACGGCCTTCGTCCTGGGCGGCCCTCGTAGTCGTCGGTGTGCGCGATCGTGTTCCACTCGCCCAGGACCTGCTGCGGAACCTCGCCGAACCGCTCGCGACAGACCGCCGTCCACCCGTAGCGGGGGTCGGTGACGAACTCCAGGAACATCCGCAGGTTCCCGAGGTGACCGCGGGCCGTGGACACCGCGAACGAGCGCGAGGTTGAGCGGAGGTGGTCGATGAACGCCTCGATCTCGGCGGCGTTCCACTGCCATGGGTACTGGCCGGAGAAGCGGGCCAGCCGCTGTACCAGGGCCAGGCGGCGGTTGATCGTGTCGTCCTTTAAGAACCGCACCCGCTGCTGCCTTGCCCAACCTTCGAGTATCGCCTCAAAGACCGTCGGCTCGGGGTCCAGCGGCACCACGTGCTTGACCAGCACCAGATGCGACGCACCCGGCAGGTCGACTCGCCCTTCCATAAGATGCATTCAATGCATCATGGATGCGTCGTGCCGGGTGAAGAGGTAGAAGACCATCTCGACGCAGTAATCGCTATATGTTCGGATCGTCCTGACCAGGGTTTTCACCGAGTTCCTCGAACTTCGGCAGTTGCATCGGATGCATCTCCGCCCGGATCCGGGCCAAGCGCACCGGGTGCCTCCACGAGCCGCGCTCCAACGCGGTGTCCACCATGATCTCGGCCACCAGCACCGGCTCCACCAGCACGACGTCCAGCGGTGTCCGCGACCTCCAGTAGGTCGTGAACCGCACGCCGTCCCAGGGGTGACCGGACCTTGGCGGTGTCAGCCGCTCGGCCAGGTCGCGGGCCGCGTTAGGCCTCAGCGGCGTACTGCGGCCGACCGGCCGGAGCACGCCCTCCTCGTCGAGGCGGCCCAGCACAAGCGTCTGCGGCCGGCGCACAGTACCGGTGATAGCGCCGATGACCGCCTCGGTGGTGTCCCGGCGGCGCACCTTGTAGAACGCACGGGCGCCTGGCACATCTGCTGTCCACTCCCCCGGATCACCAGCCCTTCGACGCCGGGCACCTGCGTCCAGGACGTCAGCCACTCGGTGGCCATCGCCGGGTCAGTCGTCTCCGGACACAGCGTCCACGGAGCGGTCAGCCCGCGGTCGGTGAACAGCCGCTCCAGCCGTGCGCGCCGCTCGCCGTACGGGACGTGCAGCAGCTCCTGGCCGTCGAGCTGAAGGAGGTCGAAGACGATGTAGTGCGCCGGCCTCTCCTGGGCGAGCCGGGCGGCGGTCCGGCCGCCGGAGACCGCGCGCCGCTGAAGCGCCTCGAACGACATCCGGCCCCCGGCCCACACGACCAGCTCACCGTCGAGGACCAAGCCGCCGTCGGGCAGGTCCGCGGCTGCGCGCACGAGGTCCGGGAAGCGGCTCTGCATGAGGCTGCCGTGACGGGACTGCAGCAGCAGCGGGCCGGGCGCCGGCCACGACGTGCGGGCGGTGGTGACGAGCTGGGCGGCGGAGAGAAGGCGGAACCGGAGACGGCGGGGCTCCCACCTGCGGATTCCGCCGGTCAAATGAGGCGAAATACTTGGCCGCCTTGCGCAGGATGTCCCGCTTGGTGGCCAGCTTCCGCTCGCTCGCCTCAAGCTCGGCCACCTGGGCCTCCAGCTGCCGGATTCACTCGTCCGGGTCAGCGGACTGTACCGGTTGTCCTGCTCTGGCCGGCGCTGCCCCACCTGCCCCGGCGGCCTCGGGGGCGACGCCGCGACGTTCCCGGTCCCGCAGCACCCACTCACGCAGCGTCGCCCTGTTGATGCCCAGGTCAGCGGCGATGCTCTAGTAGGTCGCCCCGGGCGTGGACTCGTACAGGGCCACGGCATCGGCCTTGAACTCGTCCGAATGAACCTCACTCGCACACCACCCTGATTGCTTCAACTCCGTCGGCCTGAGGTAGTGACTCAAGCAGCCGCATCAGCTCAGACTGAGACAAGGCCATCGTGTGCTCTCCGGTTGAACTGCCCGTTTACCAGGGAGACTTGCGCGATGGCCTGCCCTTGTTCAGGGAGCACTCACCGTGAGCGGCTGCACGCCCCGGGCAGACACCCGCGCATTCCAGACGCTCGACCGACGACACCACCCAGCGGGACACCATCCACCTCCGGCCGACCGATCGCCGAACTCGAGCTCCGCCACCGGCTGCGGGCCCGGGCCGAGGACCGCATCCGGGCCGCCCGCGCCACCGGGCCTGAGGAACCTGCCCCTGCACCGCACCGCCCAGAACCGGATCTGGCTGGAGATCGTGCAGATCGCGCTGGACCTGCCAGCCTGGATGCCGATGCTCGCACTGACCGGCAAGGCCAGACTCTGGGAGCCCCGCCGTCTGCGACTCCGCCTTTTCACCACGGCCGGACAACTCGTGACCACCGGCCGCCGGCGAATCCTCCGCCTGGCCCGGCACTGGCCCTGGACCAGCCACATCACCACCGCTCTCGAACAGCTCGCACTCCTGCCGAACCCCGGCTGACCGACGGATTCCCCGTCGCTACGACAGCAGCTCGACACCCGGAGCAGTGGAACCCGGAGCCGCCCCAAGGTGACACTCGGGCCCCGGGCCTGCACAACCTCGGCCCACAACGCAAAAACGGTCCACCGACTCCGTCGGCGGACCGTCACGCAAAGATCGAGGCTAGCGGCCGCTCACGACCACCCCCTGTAGTCAATCTCGCCAAACCAGACGTCTTGCCAGTCAGTCTCGAAGGTGCCCTCGTACTGGCGGGAGTTCCAGTAGAAGCAGTCGCCTGGATAGATGCCCATGCCTTCCGGCGCGCCGTGTCCGTCGAAGTACACGTCGCGGTAGACGGTGCCACCGCCCTGGGCCGAAGTCGGCTTGTGGCGCATGTCGTCGCCGTCCGGGTAGCTGTCCATTAGGAAAGACACTGTGCGCTGCGCACAGCGCTTGGTCGAGTAGTGCGACCAGCCGTCATCGTAAACCGTCCCAGAGATGCCCTCGTAAGAGGCCGACGCAGGACTTATCGCAGCGATACCCGCGAAGGCAGCGGTCGCGGCGACCACTCCTAAGCGACGCATCATCGTCATGCTTTCCCCTAACTCACACCAGTTCAGGCATGCCGCAGAGGGAAGACCTGGCTCCCCCCAGTGCCGACGGTCAATGTAACCGCCGCCCCAAGTGTCACTCCACGCATAAGGATGATCGACGATGTGACATGCATCATGTGCAATACGTGTTTGAATGGTGACTCTGCGTTCGAGAGTGTCCGAACGACGTCGACCCTCAGACCGCACCGCCCCGACGACGTCCAGGAGGCGCGCGCCCTGCGCGGCGGGACCACCGCAGAGCTGGCCGCCGCGCATGCCCGCATCACTCAGGAGTCGGCCGAGAGATGCGCACCGGCTCTGGGTGATGCCGTTCTCTCGGCAGATGCGCTCGTCCAGCACCTCGACCGGCTGAGGGTGAGCTTGACTCTGAAGCTTCTATAGATCGTCAAGCTGTAGGAGACGACCCGGGTGCCTTGCTGAATGCGCTGGTGAGGTGGTGGTAGACCGCTCGCGCGACGAAGCGCTTGAGGCATCTGAAGATGTCCTTCGTCTTGAGTCCTTGGCGGGTGCGTCGTGCGACGTAGTCGCGGGTGCGCGGGTCGTGACGTATGCGGACCAGCACGATCGTGTGCAGTGCGCGGTTGGCCTGGCGGTCTCCGCCACGGTTGAGTCGGTGGCGGTCGGTGCGCCCGGAGGATGCCGGCACGGGTGCGGTAGCGCAGAGGTGGGCGAAGGAGGCCTCGGAGGCGAGTCTGTCGGGGTTGTCCCTGCGGTGACCAGCAGTTCGCCGGCGGTCTCGGTCCCGACGCCCAGCAGCGTGAGCAGTCCGGGTGCGGTGTGAGTGATCAGGGCGCGAAGCTCGGCGTCCGCGTCTGCTATCTCCTCGCTCAGGTACCGGTAGCGCCTGGCCAGATGCTTGAGGGCTGTGGCTTTATCGAGCAGTAGCGACGTCGCTTGTCGATGGGTTTGGGAGGCGCCCTGTTTCACGGATGGGTGATGTCGACGAGTTTGGGAGGCACCCGGGTTCTTGCCAGGGCAGCATCGACATGCTCCTGGTGAGGTGCTGGTCATGCTGCGGATGTCGAAGGTCGAGCTGTACGCGGCGATCCGGCGTGACCACCGTGGCGGCATGTCGATGCGGGAGCTTGAGCGCAAGCACGGTGTGACGTGGCGGACGGTGCGGAAGGCGTTGGACTCGTCGTGGCCAGAGCCGCGTAAGAAGCTGCCGCCGCGGGCGACCGGACTGGACCGCTACAAGCCGGTGATCGACGAGATCCTGCGGGCGGACCTGGACGCGCCGCGCAAGCAGCGGCACACGGTCACCCGGCTCTTCCACCGGCTGGTCAAGGAACACGGCGCCGACGTCTCCTACGGGATGGTCCGCTACTACGTCGCGGCCCGGAAGCCCGAGATCCTGGTCGAGTCGGGCAAGGCGCCGCTGGAGGCGTTCGTCCCCCAGACCCACCAGCCCGGTCACGAGGCGGAGGTCGACTTCGGCGACGTGACGATCCGCCTCGCCGGCGAGCTGGTGACCTGCTATCTGTCCTCCTTCCGCCTCTCGTATTCCGGCAAGGCGGTCCACCGAGTGTTCGCCTCCTGCGGCCAGGAGGTGTTCTTCGAAGGCCACGTCCACGCGCTGCGGACGCTGGGTGGGGTCCCGCGAACCAAGGTCCGCTACGACAACCTCAAGGCGGCTGTCGCCCGCGTGCTTGGGCTGAGCCGGGCAAGGGTGGAAGCGGATCGGTGGATCGCTTTCGAATCGCACTACGACATCGAGAGCTTCTACTGCCGCCCAGGCATAAAGGCGCCCACGAGAAGGGCGGCGTCGAGGGCCAGAACGGCTACTTCCGGCGCAACCACTTCGTCCCGGTTCCGAGGTGTCCTCGCTCGCCGAGCTGAACGAGATGGTCGAGCAGTGGGACCGGCAGGACGACGCCCGCAGGATCGGCTCAGGTCCCGGACCATCGCCGAGGAGTTCGCGCTCGAACGACCGCTGCTGATGCCGCTGCCCCAGGAGCCGTTCGAGACCGGGCAGCTGTTCACCCCGCGGGTCGACCGCTACGGCCAGATCCCGGTCCGCACGAACCGTTACTCGGTCCCCATCCGACTGATCGGCAAGCGGATGAGGGTCATCCTTCACGCCTCTCACCTAGGGGTTTACGACCAGAACGTGGAGGTGGCCCGGCACGAGCGCCTGATTGCCAAAGGGGCCGTCCGCCTGGACCTGGACCACTATCTGGAGGTCCTGGTCCGCAAGCCCGGCGCCTTTCCCGGTTCGACCGCTCTCGAACAGGCCCGCTCGGCCGACAAGTTCACCCCGGTCCACGACGCCTGGTGGACCCAGGCCATGAAGATCCACGGCGAGCGGGACGGCACCCGCGCGCTCATCGAGGTGCTGCTGCTCGGACGCCACATGACGCACGAACATGTCGTCGCCGGCCTGGCCGCAGCCCTGCGGGCCGGGGCCATGACCGCGGATGCGGTCGCGCTGGAGGCCCGCAAGGCCGCCCAGGCCGAGACCGAGCCCGCACCGGACGCCCGGACCCTCGGCCAGCCGCCGGCGACGGTGACGTCCCTGCACGAGTGGAGACTCGCGCATCTTCCGCCGGACACCAGGCCGCTGCCCTCGGTGTCTCACTACGACCAGTTACTCCGACGCCGCCGCACCAGCGGCAGCGGCCACCGTGTGCTCGCGGCGGCCGAGGTGGCGGGTCAGAGCTCGCCAGTTCTTCAGGTGAGCGATGCCGTGCTCGACGCGGATGCGTCGTGACGAATGTGCCTTGCGCTGCCGTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGTGCCGTTCATGCCACAACGGGCCCAGCTCGGCCACGCGTTCAGCGATCACGTCGGCCGACAGGCCCGTGATCCTTCGTCTACCTTCGTATAATGTATGCTATACGAAGTTATTACGTGCCGTTCATGCCACAACGGGCCCAGCTCGGCCACGCGTTCAGCGATCACGTCGGCCGACAGGCCCGTGATCCTTCGTCTACCTTCGTATAATGTATGCTATACGAAGTTATTACGTGCCGTTCATGCCACAACGGGCCCAGCTCGGCCACGCGTTCAGCGATCACGTCGGCCGACAGGCCCGTGATCCTTCGTCTACCTTCGTATAATGTATGCTATACGAAGTTATTACGTGCCGTTCATGCCACAACGGGCCCAGCTCGGCCACGCGTTCAGCGATCACGTCGGCCGACAGGCCCGTGATCCTTCGTCTACCTTCGTATAATGTATGCTATACGAAGTTATTACGTGCCGTTCATGCCACAACGGGCCCAGCTCGGCCACGCGTTCAGCGATCACGTCGGCCGACAGGCCCGTGATCCTTCGTCTACCTTCGTATAATGTATGCTATACGAAGTTATTACGTGCCGTTCATGCCACAACGGGCCCAGCTCGGCCACGCGTTCAGCGATCACGTCGGCCGACAGGCCCGTGATCCTTCGTCTACCTTCGTATAATGTATGCTATACGAAGTTATTACGTGCCGTTCATGCCACAACGGGCCCAGCTCGGCCACGCGTTCAGCGATCACGTCGGCCGACAGGCCCGTGATCCTTCGTCTACCTTCGTATAATGTATGCTATACGAAGTTATTACGTGCCGTTCATGCCACAACGGGCCCAGCTCGGCCACGCGTTCAGCGATCACGTCGGCCGACAGGCCCGTGATCCTCCGGTCGCTGATGATCGCTGCACGAGACACGTTCCCCACCACACGACCATGATCGACGATCAGGACCTCGACGCCTCACCGCCTACCGTGCACGAGCTCGCTAGAGGTGAACGAAGCCAGGTTCTGATGTAGGTGATGTCCGCGACCCACAGCTGGTTCGGCGCACTCGCGGTGAACTGCCGCTCGACCAGGTCAGCGGGCCGGTCGGTCTCGGGTGCGGGGCGGGTGGTGCGTGGGCTCTTGGCCCGGATCACCCCGCGCAGACCAGCCGCGCGCATGAGGCGCTCGACCGTGCAGCGGGCCACCTCAAGTCCCTCGCACAGGAGGGCGGCGTGGACCTTGCGGGCCCCGTAGAGGCCGTAGTTGGCCTTGTGGATCCGGCATATCTCCTTCGTGAGGTGCTCGTCTCGCAGACTGCGGGCCGAGGGCGGGCGGGTGCGTGCGGCGTAGTAGGTGCTCGGCGCGATCGGCGCGTCCGTCTCGGCGAGGATGTCGCAGATCGGCTGGACGCCGAACGTCTCCTTGTACTGGTCGATGTAGGCGACCTTCATCGCAGTGGACGGTCCAGCTCCGCGGCGAAGAAGGCCAAGGCGGACTTCAATATCGCCCTCGCCCGCCGCAGTTCCTTCACCTCCCGCTCCAGCTCCGCGATCCGTGCAGCGTCGGTGCTGGTGGTACCGGGCACGGTGCCCTCGTCGACCTCGGCGCGCTTGACCCAGCCGCGCAGGGCCTCGGGGTGCACGTCGAGCTGGTTGGCGATCCGCTTGATTGCACCGGCCCTGCCGCGGGGTCCTTGCGGGCCTCGATCGCCAGCCGCGTCGCACGCTCGCGCAGTTCGTCGGGGTACTTACGGGGAGCAGCCGTGATCGGCATCCTTCCGAGTCTTCGATGTCTCCGTCAAGCCCGGGGTGATTCACACTGATTGCCCAACCCGGCTATGCAGGCGTTGACTTCAGCCTCCAGTGCGGCTGCCAGCATCCGCCGTGCGCCCTCGCGGACGATGTCGTCGATCAGGGAGCCGGTCTCGGCCGCCCCATCGGCATTCATCACGCTCGGCACGGGCGTGCCTTCCCGACCGGCGGTGCAACGTCGGTCTACTCGATGACCAGAAGTCGATCACTCGGGAAGGTACGCCCTTCGCGTCCAACCCGAGGCCAATCCACAAGTCATGAGCATTGCTCCGCCCGCGCAGGGCGCGCGCCTCCTGGACGTCGTCGGGGCGGTGCGGTCTGAGGGTCAACCACGTTCGGACACTTTCGAACACATAGGCACTCTTTAAACACATATTGCACATGATGCATGTCACATCGTCGATCATCCTTATACGTGGAGTGACACTTGGGGCGGCGGTTACATTGACCGTCGACACTGGGGGGAGCCAGGTCTTCCCTCTGCGGCATGCCTGAACTGGTGTGAGTTAGGGGAAAGCATGACGATGATGCGTCGCTTAGGAGTGGTCGCCGCGACCGCTGCCTTCGCGGGGATTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGTATACGTGGAGTGACACTTGGGGCGGCGGTTACATTGACCGTCGCCACTGGGGGGAGCCAGGTCTTCCCTCTGCGGCATGCCTGAACTGGTGTGAGTTAGGGGAAAGCATGACGATGATGCGTCGCTTAGGAGTGGTCGCCGCGACCGCTGCCTTCGCGGGGATCGCTGCGATAAGTCCTGCGTCAGCCTATTGGGAGGGCATCTCTGGGACGGTTTACGATGACGGCTGGTCGCACTACTCGACCAAGCGCTGCTCGACCCACGAAGTGGGTTTCGCGGTGACCGGCTACCCGGACGGCGACGCCATGCGCCACAAGCCAACTTCGGCCCAGGGCGGTGGCGGCACTGTCTACTCCGACGTGTACTTCGGCGGAACCACCTCGTCGTCCGACATGGGCATCTCTTCGGGCCGGTGCTTCTACTGGAACGCCCGCCAGTACGAGGGCATCTTGGAGACCGACTGGGAAGACGTCTGGTTCGGCCAGATCAACTACAGGTACTGAGTGGCCGCTAGTGTGAGCATGTTCGGCGCCAGGGCCGTTGACGACTTGGCGCCGAACGCATGTTGGCAGACAATCAGCTGAGCAGGGGCAAGGGAGCAGCGTTCCGTATGGAGATGCGTGGGAAATGGGCATTAGCAGCTGCTGCCGCAGTGTTGCTGGTTGCCGGTTGCGGCCGTGACAAGGACAGCGAGATCCCTGAGGGCTGGAACACCAAGGCCGAGGTGCAGCAACAGCTCGCCGAGGAACGCCAGAAAGTTTCCATGCCGCTTGGGTGGCGCTGGCAGGACAAGGTCGAAGGCGCCGACAGGGATATCTACGAAAGCGGCGCTGCCCAGGCAATTGTGCTGGACGAGGCCACGTGTGCTTGGAGCATCACCTGGCTGAAGAGTGCCGAGAAGAACGACGAGCGCGGGCAGAAGCGCGCAGCGACTGAGCTGGAGACCTTGCGGGAACTGCCGGCGTACCAGAACAACGACAGCAGCTATCGCGACCTGGTCGAAGATGCTCAGAGCAAGTCAGAACTCGGTGACACCAGCGCCCTGCGCCGGTACGTCGACAACAACTGCGAGACTTATAAATGACGGGACGCAGCCACCGTTTCCCTCGCATCGCCGGTGCCGGCCTGCTGCTCCTTGTCGGCAGTTTCGCGGGGGGATGGGTAGGACAGCAGGCCAGTGCGGACGGCGATGCCGATCTTCGGACCCAGCAGCCTCTCTCCGTCCCGACAGCGCGCCACGTCACTGCCGAGCGCGGCTCAGTCCAGGCGGTCGTTGTTCTTGACGCCACTGTCGTCGCAGCCGACAGTGGGGCGAGTCAGTCGCTGAAGCAGTCGAGCCTCGTTGAGGCACAGATCCGGCCCGAGCAGTTGGCACGCTTCTCCAGCCTGCCGTCCACGGGAAAGGCTAAGGTCGACGGTGGCCCAGCGACCACGGACTGCCGTCTGTCCGCCCTGATCACAGGCGAGGGGTCGGATATCTTGCCGCGTATCCGTTGCACACTCCCGCAACCCGTCGCCTATCCCGGCGTACGCGCCCATCTGGCTCTGAGCGCAGGACAGGTGCACAATGTGGTCGTCCTGCCGCTCAGTGCGGTCGACGGCTCCTCTAAGCGGGGGATGGTCCATCTCGTGCAGGGCGGAACCAGCCGTCCACAGACGGTGGAGCTTGGTCTCCGCGATGGTGTGAACGTAGAAATCAGCTCCGGCTTGGAGGCCGGAGACACCGTCCTGGACCCGCCGCCCTCCCTGTTCGCCTCGGATGATCAAAAGTGATCGCTTTCGAAGGCGTCGGCAAGGACGTCGAACTCCACAACGGGCAGCGTCTGACCCTCCTCGACCGGGTAGACCTTGCCGTCGGCGCCGGTGAGTTCGTCGCGGTCGTCGGGCGCTCAGGATCCGGTAAGAGCACCATGCTGAATCTCATCGGCCTGCTCGACACCCCGACCCGCGGTCGCATCCTCCTCGACGGACGTGATGTGTCCGGCTGCAGTGACAGCGAGCTGTCCCGTCTGAGGGGCCAGCATCTGGGCTTCGTCTTCCAGCAGTTCAACCTCCTCGCCAAGCGAACCGCAATCGCCAACACCGCAGCCCCTTTGGTCTTCACTACTGCCTACGACGCCAAAGAACGCACCCGCCGTGCCGTCGAACAGCTCCGCCGCGTCGGCCTGGAGCACCGCATGGATGCGCTGCCCTCAACCATGTCAGGCGGAGAGCAACAGCGCGTTGCCATCGCACGCGCATTGGTCGGCAAACCCCGCATCGTGCTCGCCGACGAGCCCACCGGTTCCCTGGACGAGTCCACCGGCGCCCAGGTCATGCGGCTACTTATCGATGAGGTCCGCCACGCCGATGCCACCTTGTTGCTCGTCACCCACGACCTCGACTTGGCTCGCGAGGCCGACCGGGTAGTTCGACTTGAGAAGGGCAAGGTGCTCGAAGAGTCATGAGGTTCCGATCCCTGCTCATGGCGGTCCGCGACGAGCTCGCCGCCAACCCCACCCGCAGTTCCCTGGCCGCTGCCAGCGTCGTGGTCGGCATCACCTGTTTGGTCGTTGTCGTAGCCCTCACCGGTTTGGGAGAACAGGCCATCCGCTCCGAGATTGAGCGCACCGCCGGCCGTGCCGCTACCTACCAGATAGACGGCCTCAAGTCCGACGACCCTAAGCTGGTCAGGACTCTTACAGACGCCATGGACCAGCGCTTGGACCAGCTTGGTATCAGCGCACACAGCCGCTACGACGGTTACAGTGCCACCGCACCCGGCGAAACCAACGCAGAGCTCTTCGCCATCGATCGTTCCTACAGCCGCATCCGGACTACGGATGTTCTTCAGGGCCGCTGGCTCAACAGTGACGACGATCATCGCTACCCGATCTCTGTGGCGGCCAATGGCGCGGCCTGGGATGCGCTGCCCAACTCCCGGCCGGGAGCAGTGACTGTCCTGCACGTAGGCGGCAGCCGCATCACTGCCCGCCTCGTGGCGCACATCGATGACGGCCGCTCCGAAGCCACCCTCTACGTCTCCTCAACTGCGCTGCATGCTGCGCAGGTCGACCTGCCGACCCCACAACCGGGCTACCTTTACGCCGTCACTCCCTCTGACGCCACGCAGCTTGCACAGGACATCGCACGCATTCCGCAGAATCTGGGTGCCGAAGGCGTCAGTCTCCACCGCGTCGACGACAGTGATGCCTTTCAGCGCGTCTTCCGCATCGTGCAGGGATTCGGTGTCGGCGCAGCTGCCCTCGCCTTGGCCGCCGGCAGCCTGGGTTTCCTCAACCTCGGACTTGCTTCCGTCCAACAGCGAGTCCGTGATTTCGGAGTCCTGCGCTCCTTCGGCGCTACCCGCCGTGCCATCTTCGTCACGGTACTTCTGGAGTCCGTAGCCATCACCTTCGCAGCAGGCATCGCTGCAGTTGCGCTGTCGTGGATAGCGATGCAAGCTGTGCCCACCGTGGGTGGTATCAGCTTTGCTCACGCCGATCTGTCTGTCTCTGCCATCATCACCGGCCTGATCGTCTCCGTCGCCCTCGGTATCGCTGTTGGGCTCATCCCCGCCCGCCGCGCCACCCGGGTCAACGTCATCGAAGCCATCCGAACCGCCTGACCGAGGTTGCGGGTTGGCCGGAAAAGCAACCAAACAGCCCCTAGTCTCGCCGTTTCAGTTGGGGTTGCTGGGTGACTGGGCGAGATTGTTCGGGGCAGTGTCGGCTGGTGGGCATGGTGAGGGCCCGACGCGGGGTCGGTTCTCCGAGGTCCTTCAGTCGAGGGTCGGTGGGGACGGCGGGTCAGCCGGCGGGGCGGGGTAGTGCGGCCAGTCGGTGGAATGCGGCGGCGAGTTCATGTCGCCAGGGCCAGGTCGCCGATATCCGCAGGCGGAGGCGGCGGCCGCCCCGGGTGATCCGGGCGGCGACGTGGAGGATCCGGTAGCGGAGTTTCTTGGGTTCGGCAGCGGCGAGTTCGCCGTCCAGCAGGAGGACAAGGCACCGGCTTGCCGACGGCGACGATCAGGCGGGTGTCGGCGTCGATGACGACCTGGTGGTTGGTGGAGTAACGGTAGTTCTTGCTGGAGGCGGCCACGGTCCGGTCACGGGTGGGGACCAGCGTGCCGTCGACGATGAGCACGGTGTCCTTGCGGAACCGCCGCCGGGGCTGAAGAGCGAGAGTCGGCCCGAGGTGGTCGACGATCCGGTCGGCCGCCGACTTCGAGACGCCGAGCAGCGGGGCGAGTTGGCGCAGGGTGAGATTGGTGCGCCAGTACGCGGCAACCAGCAGCATCCGGTCCTCCAGCGGCAGCGACCACGGCCGGCCCCTGCGGACCGGATCGGCTCCCTCGCGCCGCAACGCGGTGATCAGCTTGTTGAACTGCCGAGGACTCAGCCCGGTGAACGGGCGTATCCACGAAGGCTCTGACGCCGTGATCACACCAGCCACGGCAAGATCATCTCACCTCTGACCAACAGTTACGGGACGTCCTCTACTGATCTTTTCGTAGGTTCGGTGGGTGTGGTGGGTGGATGGTCAGGCCGGTATGGGCGAGGAATGACCATGGAAGTCGGGGGTTGGTGTTGATGCGGTGGATGCCTTGCTCGGTGGCGTCGGCGACATCGGCGAGGTGGTTGCCGGCGAGGTTGGCGAGTTCACGCTTTTTGAGCGAAGACCACAGCAGTTCCACCGTTCAGCTCGGGAGCGTAGGCGGGTAATCGTTCCAGGGTGAGCCAGTCCTGTTCGGCGGCCCAGGCCCGCATCGCCCGGCTCCAGTGGGCGGACAGGCCGTCCCAGATCAGGACCACTCGCTCGCTGTGGTAGAACACCTTCATCTGCTTCAGGACCTCGATGAGTCCGGCGGTGTCGTAGCTGCCGGGCTTGAGGTGGAAGCACAGGCGGGCCCCGCGAGCGGGGTCGGTGGAGTGGTAGCCCAAGGCCCCGGCCATCGACGCACGCTTCCAGTTCAGGCGGTGCCGCAGGAGCGGAGTCCGCCCTCGGGGCGAGTAGGTGCGGCGGATCTGAGGGAGCAGGGAGACGCCTGATTCGTCGAGGAAGACGATCCAGGCACGTGTGTTCACGGCCCCTTTTTGATGCGCGGCCACTCGTGCGCGATCCAGCGGGCGATCTCCGATTCGTCCCGCTCGACCGCCCGCCGCTCGGGACGTTGCAGGCTCCATCCCAGCCGGCCGGTCAGCAGCCGCCATACCGACGCCCTCGACAACACCACCCCCGCTGTCCGGGTGACGACCGCGCCGACTCGTTCCAGGGTCCACAGATCGGCCTCGAAACCATGAGCCTGGGCACCTTGCTCCAACGCGGCCCGGACCATCCCGACCTGGGTGTCGTCCAGCTTGGGTGGGCGTCCGGTGGCTGCCCGTCGCCGCAGGGCCGAAGCACCGCCTTGCTCCCACACCCGCCGCCAACGCCGCACACTCTCGGCACACACCCCCACCGCCCTCGCGATCTCCGCATTCGAGACGCCGTCCTCGAACAACTCGACTGCCCGAACACGACGCGCCTCCGCCAACTGAGGCCGCGACAAAGGAGGAAGGGAGGAGCCGGCAACCGAAGGGGAAGGTTGATAAGCCACGCCGACAGCCTCCCACCCACACGGCCACCACACCCACCGAACTTACGAAAAGATCAGTAGGAGATAAGAGGCAATCTGCCTAGAACAAACGCCCTCTGAAGAGTGGGTCGTTGGCGTTTTACGCTTTGAAACAGTCTTTCGGCACCTATACATGGCGGCACTCCGCACCTCCACCCTCCAACTAGCCGAGAGCGTCACCCAGGTTCGTCAAATCAAGCCACCAGTGACGGCTCTGAACTCTTGGTCAACGCTCGCTCGGTAGTCCCTTGCTGCTGGTTGAGGTCTCACAACCTCTCAGCCGCACTGGGCCAACAGATGCCCATGACAGGAGCGTTCTCAGCCAGATCATCCGAGCACCGTCGTGTACATGACTCGGTGTGTCTATGGTGTGACGGCTCGTGTGTTGTGGATGGGGTTCGTGAGTTCGAGCGACCCTGTGGAGTGCTCTGGGGAGGGCGCATGCGGTCGCGGGGTAGGTTACTCCGGTCGGTCAGAGAAGGCCGGCATCGGCTGGTGACAGTAGGCACGCTCGTTCTCGCGCTGGCCGCAGGAGCGGTATCGGCCGAGGCACTACCGACGGAGCCCAAGCCTTCCAAGTCCTCCGCGCCGACCGCGTCTGCGGACGCACCATCGTTCTCGAGCAAAGCTAAGCCTGCGCCCCAGAAGACGGACACGGTCGATACTGCTGAGCCGACGACAGGCAACGCCGTCTACGCCTACGATGCGGCGAACCGCCTGGTCGGCGTGACCGACCCCGACGGTGAGACGGCCCGTTACCGCTACGACGCGGCAGGGAACCGGCTGGGTATTGACCGGTTCACCTCCAGCACATTGTCAGTGCTGTCAGTCGTGCCCGTTCGTGCGCCGGTCGGTGCGAAGTTGACTTTGTCTGGCACCGGCTTCTCCTCCAGGGCTGAAGGCAACACGGTGACCATCGGGGGCAAGAAGGTGGTTGTTGCCTCTGCCTCTGCAACTCGTCTTGTTGTCACGGTGCCTGCGGATGCGACCAGTGGCAGGGTGACTGTGAGTACGGGTGGTTCGACCGCTGAGGGCTTAGAACCGTTTACGTTGGCTTCCGCGCCCGCCGTCTCCAAGGTAGAGCCGGCCTCCGGTCCACCCGGCACAGAAGTCACCATCACAGGCGCTCATTTCGCCAAGGCCGCGTCGGACAACGTGGTGCGCTTCAACGGTGGAACGCTGGCCGAGACTATCCAGGCCACCGACGGCACTCTCACTGTGAAGGTCCCCGCGGCAGCGACCAGCGGGCGCATCACCGTGCAAACCCAGGATGGCAAAGCAACCTCTGCGAGTGACTTCCTGATACCGCTCTCAGAGGACGAGGAAACCTTCGAGACGACCATCCGCACAGCAATCAACGACGCCCCTTCGTCTGTCGCTGTCACTCAAGCCGGCAAGCGCGCGAGGTTGTTCTTCGATGCGGACCAGGGCCAGGATCTCTCCGTGGGATTCACCCAGGCCACGTTCACTCCCTCAGGGACCGCCGAGCTCATCGATCCACGCGGCGACGTGGTGGGCACCAGCAGCAACATCCTTCCGGGCTCCGACGACTGGGAGGTCCGCGACCTGCCTGTCTCCGGCACCTACACTCTGGTGGTCAACCCCTCTTCCACTACCACCGGCTCCGTGACGGTGACGTTGTCCGAACCGGTTGGCGGTGAGCTGAGTTTCGCCGGGAACCCCGCCGCCACCGTGATGAGCAGGGCGGGGCAGGACGGATTATGGACGTTCACCGCCTCGGTGGGCGAGTCGTTCAGCCTTGGCATCGACACCGCCTCGATGACCGACAGTCTCACTGCACGCTTGTACGCACCCGGTGGAGAGCAGGTTGATTCGCTGTCGGTGTCCAAGGCCTTCGACGGTTCTTTGGATCTCGACAAGCTGCCTGCCAGCGGTATCTACACGCTGTACCTGGATCCTGCGAATGGTGCGACCGGTACAGCCACGGTCACCATCTCGCACTTTGCGTCTGCTGCTTCGTTGGACCCTCAGGCAGATCCGAAACAGCTGGCTATTAGCCGCCCGGGGCAGGATGGCACTGCTGTCTTTACCGGTACCGCCGGCCAGAAGGTTTCGCTCGGGATTACCTCCGCCGGGTTCACGACCTTTGTTACCTACTACGTCTATGCCCCTGATGGCAGTAAGGTCGACAGCTTCACCGTCTCCGCAGCAGGTACGACGGACTGGGACAGCGCGGCTCTCCCTCAGTCGGGCACCTACCAGCTGCGGATGTCCCCCGCCCGCCTGGGTACGGGGGCCTTGACAACGACGCTCTCCACGCTGGTGGACGCCGGGCGTCTCAGCTCTACCGGCTCCTCGGAGTTTGTGGACATCAGTCGTCTCGGTCAGAACGCCGAAGCGACGTTCAACGCCTCCTCGGGAGACGACCTGTCGTTGGCCGTCACCGAGAACACCTTCACCACCGTCGCCTCGTTGACGGTGACAGCACCGTCCGGTGCCAAAGTTGCCCCTTCCGTGTCCGTAACGTCCGGGAAGGCGCATACCCAAGGGCTGTCGGACTTGCCGGAAGCCGGAACGTACACAGTGACCGTGGATCCCTTCAGTGGTGCACAGGGCAGTATGAAATTGACCCTGTCCACGGACATAACGGTCAATGCCGCTGTCGACGGTACTTCGGTGTCGGCCACCGCGGCTCGCCCCGGTCAGCGAATCCGAGCCCGTTTCAGCGCGGGCAGTGACTTGGTCAGCGTCGGTCTCACCAGCAACACCATCAACCAGAGCACCGACCTCACTTTGATCGGCCCGGCCGGGGGGAACGGCGACGCGGTAGGGGCCGTGGGCAAAAGCACCACTCAGGCCGCGCATCTGGGTCCCCTGTACGCCGGGTCCGCCTACACGCTGCTGCTGGAGCCGCAATTGGCTGGCACCGGGAGCGTAACGCTATGGTTGTCCGCCCCGGCCAAGGCGGGGGCGCTGTCAGCAACCGGTCGCACCGGGACGATCAACCGACCCGGACAACAGCTCGAGTACACCCTCGCCGCCCAGGCCGGAGACGGGACGTCCGCGCTGTTCACCGGCACCACCCTCACTGGAACTACCGCTGTCAAGATACTCAGTCCCGCATCGGCGGTGCCGAACAGCCTCGGCAACCTCACGACGTCCCCGACCGACGTCGACGTGAGGGCTCCCCTCGCGGCCGGCACCCACCGGATCCTGGTGCAGCCAAGCAAACCGGTGACCGGAAGCACCACCGCTACTGCCGTCGCGGACGTGGATGGCGGCGTGCTCACAGTCGACGGGAGCAGCCGGTCCGCCTCCATCGGTACCGCAGGCCAAAATGCCCGCTTCACCTTCACCGGAACGACCGGGCAAAAACTGACCCTGAATCTGGGTACCGCACCGCCGAGCGCCTGGTATCTGTCGATTTACGGGCCCAATGACAAATGGCTCGTCAATGAGAGACCGATGACCACGGCCACCTTGGCGTACGCCCTTGCCGCGTTGCCGACAAGCGGTACCTACACGCTCACTGTGGCTCCCGCCACGATGAAGACCGGTACCTACAGTTTGGGGCTGTCGACTACCGCGGCTGCGTCCACCGCTGATTCCGGCCGCAAGAAAGAGACCAAGAGTTCGGCGAAGAAGGCTAGCGACCATGCCGGTGTTGATCGAGAAGCCTCCGCTGGTGGCACGGTGCCCACCGGCGCAGACGCATGGCAGCCGGACAAGCACAATCTCAAGGGCCTGGACTGGCTGACCCGGCGCGGCGCCACCCCCAAGACTCCAGTCCGGCTGAGGGCTCCACCGGGCAAGACCGCGGTAAGTGGACATGTGCTCAGGCTGGACGGCAAGCCGTTGGCCGGCGTCAGCGTGCGGGTCGGCACGAAAAGAACACTCACGGACGCCAAAGGCCGCTTCCTGCTCGTCGGCATCAGCCCACAGGCCACCACTCTGATCATCGACGGTTCCACCGCCAACACCAAGAAGCGTGCTTACGGCCGGTTCGAAATCCGCATCCATCCCAAAGCCGGCATGTCTGTGGATCTCGGCTTCCCGGTGTGGATGGCGCCGCTGGACACCAAACACACCGTCACCTTCGAAGCTACGGCGAAGAAAGACGTGGTCCTGACGACGCCGAGCATTCCTGGGCTCGAGGTCCGTATTCCTGCCGGCTCGGTGGTACGTGACGAGGACGGCAAGCCCGTCACCGAACTCGGGATCACCGCGATCCCGATCGACAGGCCGCCGTTCCCCCTGCCCGAGGACGGCATCGTTCCGGTCTACTTCACCGTCCAGCCCGGCGGAACCTATGTCTTCCCCAAGGGCGCCCAGATCATCTACCCCAACTACACCCGCGAGCCGCCGGGCACCCGCGTGGACTTCATGGACTACGACCCGGACGGCAAGGGCTGGTACGTCTACGGGCACGGCGAGGTCAGCGCCGACGGCACCCAGGTCATCCCTGACGCTAAAACGCGGGTGTGGGCCTTCCACGGCGCCATGTTCAACGTCCCGTCACTGCCGAACTGGCTGACCGGCTGGATGGATGACACCCTCAGCTGGCTCTCCGGTGACCCGGTCGAGCTGTCCACCGGCCTACTCACCGATACCCATACCGACCTGGCCATCAACGACAGCCTGACTCCCATCGAGATCTCCCGAACCTACTGGCAGGGAGACACCTCCAAGCGAGCCTTCGGCATCGGACGCGACCTGATCTACAACGCGTTCCTGCACTCCGAGGAACAGTACAAGGAAGTCGACCTGTATCTGCCCGGCGGGCGCAAGGTGCACTACGTACGCACCTCTTCCGGCACCAGCTTCCGCGACGCTGTCTTCCAGCCCACCAGCGCCTCCGGCAGTTTCCGCAGCACGATGATCAAGTGGAACGCTGGCTGGGAGCTGTCCTTCCCCGACGGCACCGTCTGGGAGTTCCCCCAGTACTCCCCCCTCAACGAGATACGCGACCGCTACGGCAATACGCTCACGCTTACGCGTGCCAATCGTATTCGCGGACCGATTACCCGACTCGTCACTTCCAACGGCCGTTGGATCAACCTCACCTACGATGCCCAGAACCGGGTCACCCAGGCACGGGACAACACCGGCCGCACCACTGCCTACACCTACGACAGTGTGGGGCGGCTCGAGACGGTCACCGACCCGGCGGGGAAGGTGAGCTCCTTCACCTACGACGGCACTTCGAACCGGATCGCGACCGCGAAGGATGCCCGCGGCATCGTCTACATGACCAACACCTACGACACCGTGGGCCGGGTCAAGAAGCAGACGCTGACCGAGGGCCAGGAGTACACCTTCGCCTACACCCAGACCGGCACCGGCCAGATCACCGCCACCGAGGTGACCCAGCCGGGCGGGTCGGTCCGGAAGGTGGAGTTCGACACCAGCGGCTTCGGCATCTCGGACACCCAGGCCTACGGAACGGCTCTGGCCCGCACGACCGTCTACGAGCGCGGTACTAAGCACCGCATCAATGCCGTCATCGATCCCTACGGCCGCCGCACCGAACTCTCCTATGACAACGCGAACCACATAACAGGCGCCACCGAACTTGCCGGGACCGCCCAAGCACGCTCCGCCAGCACCGTGGTCTTCGATGGCCCCTACGACCAGCCCAGCAGCATCACCGATCCCCTCGGTCACACCACTCAACTCACGTACGAGCCCAACGGTGATCTGACGAAGGTCACCGATCCCGAGGGCCGTAAAACCACCTTCACCTACACCAGCACAGGCCAGGTTAAAACGGTCACCGACAACGCGAACGCCACCACCACCTACACCTACGACAACGGTGATCTAACCCAGGTGAAGGACGCGGAGGGGCGTGTCACCCAGCAGTTCACGGATGCGGCCGGCCGGGTCAGCGCCGTCACCGACGAGGCGGGCTCGCTGTCCGCGATCACCTACGACAAGCTCAACCAGAGCCGGGAGATCGCCGACCCGCTCGGTCACACCACCGCGCTGGGATATGACGCCAACGGCAACCTCACCACCCTGACCGATGCCCGCGGCAACACCACCACCTGGGCCTACGACAACGCCGACCGCCCCAAGACCGCTACCGACCCGCTCGGCGCCCAGGCCTCCTTCGAGTACGACACGGCCGGCCTGCTGAAGACGGCCACCAGCCTCTCCGGCAAGGCCGCCACCGCCGAGTACGACCTGCTCGGCCGACCCAAGACCACCAAGTACGGCGTCAACCCGCTCGGTCAGGCCGAGTCCACCGTCACCTACGGCTACGACGCCAAGGACCTGCTCAAGCAGATTACCGACAGCCAGAACGGCACCCAGTCCTTCACCTACGACGCCTACGACCGCCCGGCCACCAGCACCGGCCCCACCGGCACCGTCAGCTATGACTACGACAACGCCGACCGCCGCACCCTGATGACCGCCTCCGGCACAAGCACCACCTACGGCTACGACAAGTCCAGCATCCTGACCTCCGTCAAGACCGGCACCCAGGAGGTCACCTTGGGCCTGGACGCCGCAGGCCGGGAGAAGAGCGCCGCTCTGCCTGGCGGCATCACCCGCACCACCGGCTACGACACCACCGGCGTCATCGAATCTTTGACCTACGCTCAGGGCACCAAGGCCATCGGCGACCTGACCTACACCAGGGACGTGCGCGCCCTGCAGACTGGCCTGACCGGCTCCTTGGCGAAGATCGCCTTGCCCGCCGCGGAGAGCGGGACCGAGTTCGGCAAGGACAACCGGATCACCACCTACGCCGGCCGCACCTTCACCTACGACACCGACGGCCAGCTCAAGAACGACGGCATCCGCACCTACACCTGGAACGCCCGCGGCGAACTCACCAACCTCATCAAGGCAGGCACCGCCTCCTCCTTCGCCTACGATCCGCTCGGCGGCAGGATGTCCAAGACCACCGGCGGCACCACCAACCGCTACCTCACTGACGGCAACAATCCGCTGGTCGAGCAGGACAGTGCTGGGGCGACGAAGGCGACGGTGGCCACCTCCGGCCTGGACGAGTTCCTCACCCGCACCGAAGCCGGCAAAACCCAGATCTATCTCACTGACGCTCTCGGCACCGTGGTCGGTCTGGCCAACACCGATGGCACCATCGCCACCAGCTACGCCTACGACCCGAACGGCACCCCCACCGCCTCCGGCGCCACCTCGTCCAACCCCTACACCTTCACCGGCCGCGAAGACGACGGCACCGGACTGCTCTACTACCGCAACCGCTACTACGACCCTCAAACCGGCCGCTTCATCTCCCAGGACCCCATCGGCCACGCCGGAGGCACCAACCTCTACCAGTACGCCCTGTCCTCCCCCACCACCTACACCGACCCCACCGGCAACAACCCCATGATCGCTGGATGCGTCATCGGCGGCCTCTTCGACGGCGGCATGGACTGGCTCGCCCAACGTCTGTCCGGCCGCAAAGTCAACTGGGGCCAAGTCGGCCAATCCGCCGTCATCGGCTGCCTCAGCGGCACGCTCGGCGCCGGTATCGGGGCCAAGATAGGCAGCCGAGTCAACTGCACCTCCCCCAACAGCTTCACCGGCGACACCCCTGCCCTCATGGCCGACGGCACCCACAAGCCCATCAAGGACATCAAAATCGGCGACATCGTCCTCGCCACCGACCCCGAAACCGGAGAAACCGGACCACGCAAGGTCACCACCCTTATCAATGGCGAAGGCTACAAACAACTCGTCGACATCACACTCAAAACCGACGAGTCCAAAGACTCCTCAACAGAGAAGATAACCGCCACCAACGGGCATCCCTTCTGGGTCCCGACGCTCCACCGGTGGATAGAAGCCGACGATCTTAAGGCCGGACAGTGGCTGCAGACCAGCGCTGGTACCTGGGTCCAGATCACTTCCGTACGCCACCGGACACAGTCCGGCTCGGTCTACAACCTCACCGTTGACGATCTCCACACCTACCATGCCGTGGCTGGCGCCACACCAGTACTGGTTCACAACTGTGGCAGCAAAGCAGGCGAAGCAATCGTTCATCTTGACCGAACCGCTGGGCATGCGTCGATCACGGTGCGCCATGGGGATGACATCCTTCATACTGAACAGGCCGGTGTGCCTGGAACACGTGCAGTTCCGCAGAACTTCGTCGGCGAGCTGTCCGATTTCAGAGTCGATGTTCGCATTCCTCTCCCTAACGCGAGCCGTGCAAGGTCCTACCAAGACGTCACTCTCGGGCGGGACTTGGGCGCTTATGATGAAGCGACCAGAAGCTGCATCACCTACTGCGCCGAGGTACTGCGGGCGGGTGGAGTGCAAGGCATCCCCATAGAAGAGGGAAGTCTCGCAATTACGAGGTGGCTTATTAAAATGCACGGGTAGCGACTGCGAGAGCTCGGCAGAATGGAGAGTGGCAATGTCCTTGCCTGACGGTTGGGAGTGGCTGGACGAGACTCCGTCCGAGTGGTCTCCCCCCTCAGAGCTGCGCACCCCAACAGGGTTGCTCCGAGTTGACCTGCCGATCAAAATGCTATCGAGCAACACGCTGGGGAACGACCTCATCGAACTGGTGGGTCGCCTGCTGAGCGAGAGTGCCCGCTTCAACATCTGGTTCGGCTCGGAGGCTAAAGGTAAAGCGAATTCTCCGAAGCAGCTAGCGGTGCTGTCACAGACGATGAACAAACAACTGCACCACATCTACGAGGCTTGGAAGCCCTTCATCGGCGCCTATAAGGCATCCGGTGGGAGAGTGGGAACATTTAAGTCCGAGGAAAATGCACTGCGGCAGGCTTTGACCGACGCAATAAATATCCTTTCCGCAACCCGAAAAAGCTTCCGGGGTGGCGACTGAGAGGATTCCGCCACTCGCCTTCGAAGCGTATATCTGTGTAACGGGCAGTAATCCCTGCGGTATGCCCGCTGCGTGAAGTATGCGTAAGGGGCGGCGGGCTGCCCGACGAGCAACGGGCTCTTCGCGAGAGGCTGAGGGCGGAGGGGCAAAGCGGCCTTCCAGACAACTGTTTGACGCACATCGACCGACGACGCTTTTTCATCCATGCCATCAGTCAGCTACAAACCCGGTTGTTCTTCAACGCAGACCACGGTGAGGCACCTGCGCTCCCCTAGATGGGTTCTTAGGACGATGACCAGTAGACGCAAGCTGCTAACCGTCTCGGCGGCAACGGCCGCTGGAGCCGGCGGTCTTACCGCTGTCGGCGTCACATCCCTGCCTAACGGCTCGTCCAACCGACAGAAGAAGGCGCCAGCCCATCTGCGCGGAGTGGTGCCGCTGCCGTATGCGCAGTTCATCTCATTCGACATCACTGGGGAGAGCGAACGCGTCGACGCGTTGCGCGCCGCACATCAAGCCATCATGGCGATTGACGGTGGCAGCGTCGCCGCGTGGCTGGCACTGGGCGAAGGCGTATTTGCCTCTTCCACAAACAAGCCGCGGCACCTGAAGCGGATGCCATCGTTTGCAGGTGACGTACTGGACCCTGTTCGGTCACATGGCGACCTCATACTCCACATTACTGGATCCTCAGCCCGTGTTGTACAGCAGGCCGTCGAACAGACACTGCGTGCACTGCCACAACAGCAGGTGCGCTGGCGCGCGGACGGCACTCGTCCTGAAAACCGCATTGAAAACGGCCGAGGCCTCTCCCGTAACCCGTTCCACTTCACCGAAGGGCACGGAAACCCCGGCACCGCGGCCGAAATCACCGAACGCGCGACCGTCAGGGATTATCAGGGTGAGCCCTCTTGGGCCATCGGAGGCAGCTATGAGGTAATCCGGATCATCCGGCTCGCCACCGACTTCTGGGGCCGGGACACCATCGAGGAACAGGAACGCATCATCGGCCGACGCAAGGAAGGCCGGTGGCTGGACGGCACACCCAGCACCGAACGGGCCATATTCGCCGCCGATCCTCACGGTAAGACCACTCCACTCGATGCACACGTACGCAGAGCAGCACCCGACCGTCGCAATCCTCCCCCGACGGTCCGACGCAGCTACAACTACCACCGAGGCCCCGACGAGCAAGGGCTAATCTTTTCCTGCTTTCAAAGTGACTTGAAGAAGGGCTTTGAAGCGGTACAGCGCAGGCTGCAAGGCGAGGCCTTGGCCAAGTACACACTCACCGTCGGAGGCGGCTATTTCTTCGTCCCGCCACCCGGCGACGCATGGCTCCGTGCGACCGCAGATTGAAGTTTCCCCTGGTGGGCACCTGGAAGACTGAGTCGCGTCCGCTGGACTGGTGGTATCGACACCCCCTCGGTTACCTCATCTTTGAGGCTATGCGGTGAGTTCGGTGGGCAGGGTGGTCTCGTCAGACTTTAACGAGCTCGTGCACGGTAGGCGGTGAGGCGTCGAGGATGGCGGCGGGGCTCGGTGTTCACATCTGCCGCGCCGACGTCAGGTCCGCAGTCTGCTGGTGGGACAGCAGGGCGGCGACGGCCTGGACAGTGTCGCTCATGTGCTCGCGGCGGCCGAGGTGGCGGGTCAGAGCTCGCCAGTTCTTCAGGTGAGCGATGCCGTGCTCGACGCGGATGCGTCGTGACGAATGTGCCTTGCGCTGCCTCGTATAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCGCCAGTTCTTCAGGTGAGTGATGCCGTGCTCGACGCGGATGTCGTCTAACTTCGTATAATGTATCCTATACGAAGTTATTACGCTCGTTGGAGGGGCGGTCAGGCAAGACCGCCCCTGGCACACCACCAGCCCACTACACTCCGGACGACGCCTGTGACCAGGCCAGATAGCGAAACGCTGCTGGAGTACTAGCGCGTGTCTCTTTGATGGGTTGGTCAGTTGATCGGATGTGTCCGTCCGATTAGTGATCACCGATGCGATGTGGGACCGGATCGAGCCGCTGATGCCGGCGGATCCGGTCCGCGGGCGGCGGTGGGCCGACCACCGCCGCACTCTTGAGGCCATCGCGTGGAAGTACCGCACCAACTCGCCCTGGCGGGACCTCCCCGACGAGCTCGGCTCCTTCCAGACCGCTCACAAGCGGCTGATCAGATGGGCCGTCGACGGCACCTGGGAGATGATCCTCGCCGCCGTCCTGGCGGCGGCGGACGCCGACGACGACATCGACTGGACGGTGTCGGTGGACTCCACGGTCGTCCGGGCCCACCAGCACGCTGCCGGAGCGCTCAAAAGGGGGCGCCCTCCCGCGGCGAGCCCGCCGATCACGCGCTCGGACGCTCCCGCGGCGGGCTGAGCACCAAGGTCCACCTGGCCGCTGACGGCCGCGCGCGGCCCCTCGCCTTCACCGTCACCGCAGGCCAGGCAGGTGATGCACCCGCCTTCGAGACGGTGATGTCGCGGATCCGCGTGCCCCGCAGGGGCCCGGGCAGGCCACGGACCCGGCCCCTGGCCGTTCTGGCCGACCGCGCGTATTCCTCACGTGCCATCCGCGCCCATCTGCGGCGCCGGGGCATCCGTGCGGTCATCCCGCAGCCGTCCGACCAAGTCGGCCATCGTCTGCGGCGAGGCCGACTCGGCGGCCGTCCGCCCGGCTGCGACAGCGAGGCATACAAGCAGCGGAACAGCGTCGAGCGGTGCATCAACCGCCTCAAGCAGTGGCGCGGCCTGGCTACACGAACCGACAAGCTCGCGATCGCCTACCAGGCCGCACTCCATCTCGCGGGCATCCTCATATGGACCCGACGCTGACCAAAGAGACAGAACCTAAGTGAGCGTTTGATTCCCTTATGTAGGTATTTGAGGCAGGTCACGTCGGTGACTCGCCCGCCACATCACGCCCTGTTCATGTGGATAAGCCCCGAATAGCAGGAGTGAACCGCTTACGCGGCGCATGCCTTCGCCCAGGAATCCACCGTCTCATTTATTAATGCCCCGGCTTACCCCGGAGCCTCCACCGGCATCCCGTACGCTCTGCCACCCCTGGCGAAGGTCTTGTACTCCACCCATATGCAGCCCCGGCGACGCTACCCCAGCGACCTGTCCGACGCCCGATGGGAACTCATCCGCCCCACCCTCCAAGCCTGGCGAGACGCCCGAGCCGGCATTCGCCGCCCCACCCACAGCCTGCGCGACCTCATGGACGCCATCCTCTACGTCGACCGCACCGGCATCCCCTGGCGCTACCTCCCCCACGACTTCCCACCCCACCAGACCGTCTACGGCTACTTCGCCAAGTGGGAAGCCGACGGCATCTTCGACCAGCTCACCGGGCTCCTGCGCCGACTCGTCCGCGAAGACGAAGGACGCGACGCCCGCCCCAGCGCCTGCCTCCTCGACTCGCAGACCGTCAAGACCTCCGCCAACGTCCACCTCGCCGACCAGGGCTTCGACCCCGCCAAAAGGATCGCCGGACGCAAACGCCACGTCGTCACCGACACCCTCGGCCTCCTCCTCGCCGTCCTGGTTACATCCGCCGCCGTCCACGACTCCACCGCCGGCACCCACCTCCTGGACCACATCGCCACCCACCACCCCCGCGTCTCCAAAGCCTTGGCCGACTCCGGCTACAAGAACGCCGTCATCGAACACGCCGCCACCCGCGGCATCGACCTCGAAGTCGTCCACCGCACCCCAGGAAGCCACACCTTCACCGTCCAGCCCCGCCGCTGGGTCATCGAACGCACCCTCGGCTGGCTCATGCACCACCGCCGCCTCGCCCGCGACTACGAAACGCACCCACACCGATCAGCCGCCATGATCCATATCGCCGCCATCGACCTCATGAGCCGCCGACTCACCCACGAAGCCACCCCTAACTGGCGCGACACCTGACCCAAACCAAACGGACACCAACGAATCAAACGCTCACTGAGGTCGTGCGGGTCACGCTCGAGGGGCTCGTAGCCAAGAGCCAGGCTGAGCGCACCAAGCAGGGCAACTCCGTCTTCTACACCGCTCCCGCTCCGAAGCCGGCCCCTGCGGTCGAGACCGAGTCACAGCCTGAAGACGCTGACCGTTAGATGCGTGTGGGGGTTGGTGCACCCGCCTTCAGCGAGGACGCCAGGTGCGGACCTCGAGGTGGAGAATATGCGCGTCCGGACGGATGCGCCCGGTCTCGACCAGCCATCGGTGGACGGCGGTGGTGACATCACCGCCTGCGGCATCCACGCGGCGGGCGAAGTCGGCGGCATCGAAGCCGCCTGTCTGGGCGGAGCCGTAGGAGCGTTCTTCAGTGTGGTCGGCGCGTTGGATGACGTCGCGGCGGATGCCCGGTGAGTCGGTGCGGCTGCCGGCGGGGTGGAGATAGCCGGTCTTGGCAAGGCGGACGGTGAAAGCCAGACGCAGGCCCTGGCGGGCGGCTTCGGCGATCAAGGGACGCAGACGAGTGGATCCGGAGGCGATGGCCTGGGCACCGACGCGGCCTGTGCCGGTGCCTGTGGGCGTGATCAGAACGGCTTTGGTGCGCACACGGGCGCGGGTGCCAGAGGCCGTGGTGCGGCGGCGGGTGTGGCGGGCGGCGATGGCGGCGAGTTCGGTCAGGTCGGTGATGCCGCCGGTCTCGACGGCGGCGAGTACCTCGCGCAGGGCGGTGACGAAGGCGGCGCCTTTGTTCTTGGTGTAGAACTGCGAGACCAGGGAGGGGTCGCGGTCGATGATGCGGGCGATGTCGCGTTTGGTGTAGCCGACTGCCTGGAGCCGGTCGGCCAGTCGAGCCGCCTCGTTCAAGGACCTTTGGCTTGTGGCGTGGCGTCGGCGGCCGGGGGTCATCAGGGCTCCTGGCTGGTGGTGAGGGCGGTGCGTCCAGCGTCCCGCAGGGTGAGGAGTTCTTCCTCGCCGGTGGGGGCGGGCAGGGGGCCGGTGAGGTGGCCGCGCAGGAGGTAGTCACCGGGCTGGTGATGGTAGGGCCAGTTTTGCCTCTCGGTGAGGTAGAGGGCGTCGGTGCGGAAGGCGACGACGCTGCCAGGCGAGGTGTGCAGGGCTCCGGCGTAGGTGTTGTCGTCGCGGTGGCGTTGGGTGAGGAGGGCGGCGCGGGCGCCGGACCAGATCGTGGCTGCCCATTCAGGGTGGGCGTTGGGGTCCCGGGCGAACCCGGTGGGCTTTTGCCAGGTGATGTGCTTGTCGTCGAAGGCAATGATTTCAGCATCAGGGGGTACGTCGCGTTCCATATTGCGGGGGGTGGTGCCGGTGACCATGCGGGGGCGCTGGGCGAAGGCACCGATGCCGTACAGCAGGATGGAGCGCACGGCCCGGGAGGCGAGATGGGCGGCGCGTGCTTGCTGGGGGTCGCCGTGGTACTGAGCTTGGGCGGAGAGGTTGGTCCAGGTCTCTTTGAGTTTTTTGGCCCAGTCTTCGAGAGGTTTGCCATCCTCCCACAGGATGCCGTCGAGGATTTCGATCTTCCATGGCTGGATGGGGTTGGTCAGGGCAGTGTGGACCTCTGGGCCGCCGGCCCAGGTGGTGAAGGTGGTGCCGGGCGCGGCGGGGTAGTGCCAGGCGCGGTCGCCGGGGGCGGGGGCGGGCAGGAGGCCGACGTGGTTCCAGGTGTCGGGGACGGTGACGCGTACATGCCAGTGGCCGCAGCCGTACAGGGCGCGGATCTGTTCCTTCTCGCTCCAGGAGGCAAAGGTGGTGGCGGTGATACGGCGGGGGGTGCCGACCGGGGACTTCCAGGTGTGCTTGGCGTAGGCGAAGGTGCGGTCGTACTCGACAAGCCGGGGCAGCTGTTCGGGGACGCGGGGCGGGGTGATCAGTTCGTTGCGGCCCTGGCCCGCGGTGGCGTGCAGCAGGCCGCGCAGTTCCTCGGACAGGACGGGGAAGCCGTCGGCATGTTGGCCGCGGGTGGGGATGGTGCGCGTCCACAGGTCGCGGCCGGTCTGCGAGGGCGAGCCCATGATCACGGCGTCGTTCCAGTGGCGGCGCAGGGCCTGCCACAGTAGGACGAAGGCGTCGCGGATGGTGGCGGGATCATCGCCGTCGGTGTCGAACCACTCCCCCACCGAGCGGATCTCGACATGTTGGTCACTGTTTTCGCGCTGGTAGCGACCGACGGGGTTACGGGCGTGGACGAAGTGTCCGGCCATACGGTCGCGGCCGCGGCCTGTGTCGGTACGCCAGCCCGGAATCGGTGCGCTGAGCCAGGCGGCGACGGCATCACGGAGGTAGGGGTAGCGGTCGGCGTCACGGTGCCAGGGGTCGCCGGCGGTGATGTAGATCCGCTCCACGCCGTCGGGGATGGTGTGGAAGACGGCGGTGAGGATGGCTGCGGCCGACCGGTCGGCGAGGTCAAGGTGGTGGGTCTGGTTGCGGTGGACCAGCACGCCGGTGGTGGCGTCGAGGAAGACGGTGGAGCGGGCCTGCTGGGTGAAGTTCGGGCGGGTGGAGGCCAGACCAGCGGTGTGCGTGAACCAGGCGTCACCAGCCTCCCCCTCGGGAATGCCGGGCAGGGTGCGCGGCCCGGCAGGCGTCGCCGGGGCAGCGGCCGGAGGCGCGGAGGGCTCGGGGTGAGGGTGGGCGGGGAGGATGACGGGCGCCGTCGCACCAGGCTGCCCGGTCGGTCGCGGTTCGGTGGCACCGAGGGCCGGGGCCTGGGCCTCGGGCTGGGCAGCGGGCTCGTCGTCTTGGGCGAGGTGGTCGGGGGCCAGCGTGGGCGCCACGGCGACGACGTCGGCCACGCTCAGCCCGGCGGCCGGGGCGATCCGTTCCGCCTTGGCCTTGGCATAGGTGGCCAGGTGGGCGATCCGCTTGTCCCGGTTGGCCTCCAGCCTCGCCAGTTCCGCCCGGACCTTCTTGACCTGGTCCCGCACGGTGCGCAGCTCGGCGAGGCCGGCGTTGTAGCTCTGGGCGTCCATCGGTTGCTTCCTTGTCCGGGCTGGCAGGTCAGTCCGTGCTGGTCGTGGGGACATACGCGATCGCTCCACCGGAGTGGGAGGCGAGCCGTGTGCCCAGCAGGAGTTCAGCGAGTTTTCGGTCCCTGTTGGTGCGGGCAGTGATGGTGAGCCGGGGGGTGGCCAGGTCGGTGACGTAGCCAGCCAGGCGGGCATCGGGGAAGGCGTAGCGGCCCTCAGCGTTCCTCTCCCACCGCTCCAGACCCGTCAACACGGCCACGACATAGCCGGACAGGGTCACCGGCAGCACGCCTGCGGCTGCGACGCTGGCGGGATCACACCGCCACCAGCCTCGTAGTGCCTTGAGGAGGTCCTCGGGGCCAAGGGAAGCAGTGAAGCCGATCCACTCCCGCTCAGGGTCATCGACCGGCTTGGCGACGTCAACCCGCAGTACAGGGACCTCTTTGACGTCGAGCTGCTGCAGGGCAGCAGAGGGGCGTGCGCTGAGCGCCTGTACGACAGAGAGCGGAGTCATGACACGAACCCCGCGCCTGGAAAGCCCCGGCAGTAGCCCTGCCTGTACGAGGCGGCGAAACGTCGTAACAGCGCAACCGAGTTCCTCGGCTACCTGCCCGGTCGTCAGCAGCATCATCCCTCCCTCCGAATATGCGGACTCGAATATCAGATCAGGCACTGATGGTATCTACGAGGCTGAAGCGCGGTCAAAATCCCTGCCCGACCGCTCACCCGTCTCGGGCTGACCACGGCTAACAGGCCGGCTGGGAGCAGGAAGGCTCGTAGAGTGGCGCTCATGACCGATCGGCCCGGAAGCAGCACCATGACCATCGCCCTTGCAGCCCCGGGCGACGGGCGAGCGGCAGTAGCGCTGGGCGCCCTCGCCGTCAGCGGCCATGGAGCGGCTCCATCAGCCCTGGCCCAGGCCATCGACACGCACGGCGGGCAAGTGCCTCTGCCCTTCGGCCGTGGCCGCTGTCTGATCGCGCGCATCGGGGGCACCGTGGCGGGGATGGTGTACACGACGCCTGCCATCCGGTGGATCCAGGAGCATCCGCCCGCCCAGCGGGCCGCTCTGGTTCATTCACTCGTCGAGATCGAGCTCCTGGCCGTCGCTGAATCCCACCGCGGCCAGGGCATCGGCACCGAGCTGCTCGCCACGGCCGAGGAGACAGCCCGCAGCGCCGGCAGCCACCTGGCCCTCGCCAAGGTCCGGATCGGCGCCTTCGCCACGATGCGCTGGTACCGCAAACGCGGCTACACCATTGCCGCCCAAGCAGAACCGGTGATATTCCGCACCCGAGCGGGATTCGAGTCCTGCGACGACGGGTCGGACGGCTACCAGCTCGCAGTGAAGACTCTCCAGCCAGGCGTGGTCCTACGCCGCCGTTCGGAACGTGGCTCCTCCATGCTCGTCGCGGAACACGTTGCCTCAAACCCGGGCAACCGATGACGCCGCCGCGCACCAAGCCCTGGGGCCGGGCCGGACGCACTCCTGTGGCGCGGATAGCGAGGCCGGGAGTACGGACGGGTCTCGTTGGTAGGCATGGCCCCTATAGGCGCGAGGGAACGGTCGCGGCTGGTCTACGCCGGTCCGCGAGTACCACGGCCGCGGATATGAGCCGAAGAACTTCGGCTGACGCTTTTTGCAAAACCTGCTCGTCCGAACCCGCATCCAGCTTGGCGGCCTGATCGTGCTCGTCTGGAACAACATGCGCTTGCACCTGACCGCCGAGATGCGGGAGCGGGCCACCGCCCGACCCACGATCTCCTAATCCCGCGACTCGTTCTGCTGGCAGGCATTGCACACGTTGTCGTCGTTGTACTCGTACGGGGTCTCGGATGGACGAAGGTGTGCGTTTCGGCATGATGTGCACAGGTCTCCTCCGCAGGTGCGGCATCCTACGTAGCGGCCGCCCGCATACTCGTAACGCCGTTTCTCGAAGTCTGGGCTGTTGCAGGATGTTTGAGTGATTTGCTTGACTTCTGGGTAGATCATAGAAATAGGGTAGGTTTCTTTTAATTTCATCTGGTTCAGGTTTCGACCTTCGGGGAAGGTTCGCAGCCAGTCTCCTTGCAGGTGGAGTTCGTCAGTTCCGCATACGCGCACGAGGGTCAGGCCTTCGGCGTGTGCCTTGTACGCCTTGGACCACAGGTTGGCAAAGGCTTGCGAGCGGATGACGTGCATCCAGTCGGGGCGACGCAGTTCCCTGTTCTGCGTCGACTCCCCCAGGGTGGAGACGAACTTGGCGTACATGGCTTTGACGTACTCGAGCGTGACCTTGTCGTTCTCGTCGAGGGCGCGCGCTCGGGCGTCGCGCAGTGTGGTACGGAACTTTTCGAGCAGGTTTTCGGTAGCGCCGGACGTATAGGACTCATGGATGACAGGTGGATCGCATAGTGCGTGTCCGGGTCCTGACAGGCGCAGCAGGAGTCGCAGGGTGGGCTCGGTGACCCATACAGGGCCGGGTTCCTGTCGTGGGCCCATGGGGTTGGGCAGGTAGGCGTCGTGTTCCCAAGGCGGGGGTGTGATGAGGTGGATGCCGGCGCGGCGCCGGTCGTGGTGTTCGGGGTTGCTGGGTTCGAGACGACCGAGTGGTAAGTGGGTCTTGAGGGCGGACAGGAAGGCGCCGTTGATGTCGAGCGCTGCGACCGGGCTGGTGTGTTCTGGTGCCTCGGGGCGTTGCCAGTTGAGACGTGCTTCCCAGATGAGGTCGGGTTCGCGGGGGCCTGGTTTGCGGAGCATCCCTGGCAATGCAGGGTGGTGGACGATGTCGTATCGGCCTCCTACGCGGCAGGCGTTGAGCAGGGCCATGGCGTCGGGGATCGCACGGGCGGTGAGTGCTGCGGTTGCTTTGTGTGGGTCACCGTCGTGAGCGGCCAGTGCCGCGGTGACGTTCTGACTGATCAGATCCTGGCTGGTGCTTGATCGTTGTGGTGCGCTGCTGCGGGGCTTGGGGATGCGGTTGTCCGGTTTCACCTCGTACCGGGCAGGGCGCGGGGGTGCGGGGGCGGGGATAGCAGCCTCGGCGCATTCTGCGGCAGTCGCATGCCGATCGCAGTGAGGGCTCCGGCTGGCGCAGCGATCAGGTTGATTCTCATTCGGGCACCCTCAGGTAGCAGTGTGGAGCGATGACTTCGACGTGTGTGTGATTTGCTCAGCGTGGCAACCTGGGCAGCGAAGGGCCTCGTCTGCCTTGGTTCTGTGCGGTCGGCGACCGGTCCCTTCAGGGCGCTGAGGGCGGCAGTGTGGGGGTCTTGCGACGTGACCACGAACTGGGGCTCGGAAGGTTGCCGTTGACGACGATGACTGCGACGAGTGAAGGCGCCTCGGGGTTGGTCAGTCCGTGAAGCGCTGGCTGGAGGGTGAAGAGGTAGTTTTCCGGAACGCCGACGGGTGAGGCCTTACGGCTCATGTCCAGGATGCAGAGAATCGAGAGGCGTGCGCCGTCGGCGGCTGCGTACTGCGTTGGCTGCCCCATGTACTTGCGGGCTCTGTCTCGGGTGACCGGGGTGTTGCGCTCGACTTTCAGCTCGGCGGTGATGCCATCGTGCCGGACATCCAGGTAGCCCAGGGCGAGTGGGGTGCCTCGTTGCAAGCGCCCGCCGAGTTCCGGTTCTGCCTGGAGTTCCTTGTACAGGTCGTCATGAAATTTGCGCTCGGTTACGTGGCTTCCGCGCTTGTAGTGCTTGTTCCACGTCATGGTGAGGCCGGTGCGGCAGATGGCGGTGAAGAGGCGGCAGAAGGCTTGGAGCTGGTCCTCGTCGTAACCGGCCCGGTGCAGATTTTCGTAGAGGGCGAGCAGCCGCTCGTCGAAGACGGGGAAGTTGGTCAGGAAGTCGCGTGAGGCGTCGAAGGGCCGGAATCGGATTTCGCGGTGTCCGGCGGTGTCGAGGCTCTCGGTAACGGGTTTGCCGTCCCGGGTTCCGCGCCAGCGCAGCTTGACCGAGAACGGCGGGGCGGGACTGCCTGCGGGCAGAGCGAAGCGGAGGATGAGCGTGCCGGTGGCGCTCAGTGTGTCGGGGCCGTCCGCGCTCGGCGGGCGTGTCCAGAGGTAGGTGGGCGTTTCCGCTTCGTTGGGGGTGAAGTGGCTGAGGAGTTCGGCTTCGAGGGTCTCGGCCCACTCGGGCCAGGAGCCGGTGCGTACGTCCAGGCGGAGTTCGTATACGGTCGAGTGACGCAGGACCTGCGGGCCGGTGACAAGGCGTCCGTCCACGCTGGCCAGTACGACTGCAACGGTCGGCTGGTCCTCGACCAGCCGGGTGTCCGCCTCGTTGCCGAAGACGGTGTGGGAAGTGAGTGGCGTGCGGCGTGGGCCGCGCGCGATGACAAGTGGCAGGGGCAGGGCGGCCCACTCCGCCAGGAGGTCGGCCACGCCGCTGGCGTCTGCAACGGCTTGGACCTGCCGCAGAGCGGCTATCAGCGGTCCGGCCAGTGGGTCAGTGCCGTGGAATCGCTTCTCCAGTTCGGTTGCGGTCACTGCTGCGCGGCGGCGCGCTGCAGTGACCAGGGCGTTCATCTCGATGGTGTCGGCGTCCAGTTCCGCTGCGTCAAGTCGGATCAGGAAGGCGGCCACCTCGCACAGGGCGGCGAAGCACCGGCCGTAGGCGGCGGTCGCCGTTGCCTGCTGACACTGCTCTCTGAGCGTGGCTGCGGTGCTCTGCAAGTGGGCTGCGCGGCCGCGGAGCGCGACGGCCGGGTCGCTGTCGGAATGGCCCTGGCCTGCCCCGGCAGCCGGTACCAGCTCGTGGCCCGTGAGAAGGCTGCGGACTGTGACACGAGTGCGGGCTTGGTCCGCCAGGGCGCTCGCATCGTTGTCTGCTCCGATGGCTTGAGCAGCATGCGTCAGTGCAAGGGCGGTCGCACGCATATCTTCTCCGGCCACCGCGGCTGCATCAAAGGTGGCCGCGGCGGCGATCAGGGTGAGCAGGGCTCGGTGGAGGGTGAATGCAGGCTCGTCCGGGGTTGTCTTGAGGACACTGTTCAGGATGGTGGCGGCATCTCCGGGGCGGGCTGCCCGCCAGGCGACTTCGGCGTATTCGGCCGCACCGACCACCTGGTGTGGCCCGAGTTCGAGAGCGGCCGCCTGAAGATCCTCCACCGTCAGGCTGGCCAGGCCCGAGCCGCAGTTAAGCAGCGCGCACAGTTCCAGGTTGTCGTGGGCGTTGAGCCGGTCGTTGACGCGCGGGTCGCGCACTTGGCGCAGCCGTAGCTGGGCCATGGCCGGGGTGGTGGCGGTCTGCGGCAGCCAGTCACGGTTCAGGGCGTCGCGTAGGTCGTAGCCGTCGAGGTCGGCGGCGCGTCGGAGGATTTCCTGTTCCGTGTGGATCCTGAGGGCTTCATTGCCTCGGGAGTGCTTGGAGGCAGCCGCCATGGCCTTCTTGACGGTGTCCGGAAAGCGGGCGATGTCTACGTGTTCGCAGACCGACAGGGCGTAGGCCAGCAGAGAGGCGCTGTCCTCGGTGCTCCAGTCCAGACGCAGGGCGGTGTCGAGGACACCGTCGATGACGCCTAGGTAAGGGTCGGTGAGCAGCGCTGGCAGGAGGTCGGAGATGCTCGAGGGCAGCTGATGCGCGCGGCCGATGTCCGCCCAGGCGGTTAGCGCTGCCGACCGCGAGGCTACATCGGAGTCGACGATGTAAGTGTGCAGGAGCGGGATGATCATCCGCAGCAGGCCGGGGTGGTCGCCGTGGCGTCGTCCGATCGTCCCCAGGAGCGGCAGCAAGCGCGGCACGATGACGTGTTTGCGCTGGCTGTCGCGTTCGTCGGTGATGGTGTCGATGACCGCGCCGCATACTGCCGTTGCTTCGATGGTGGCGATGTGCTCCAAAGCGTCCAGGAGCCTGCCGATGCTGGATGCCAACGACTGCCGGTAGGCCATTCGCTCCAGGAACTGCAGCTCCGGCGGGGCCGGTTCCGGGGCCGCCAGGAGCGGGGTGGGGGTGGTATTCGCCGACTCCAGTGTGTCAATGGCTGTCAGGGCCGCACCCAGGAGGGCAGCAAGCTGCGGCTGCGTCCAGGCCGGATGGGTCTGGGCCAGCTGCTTGATCAAAGTCGCGGCCGGGAAGCGTACCTCGCCGCCCCAGTCACCCCCGACGCGGGTCAGACACGTGGAAAGCAGATACTCAAAGACCTCCTCTGCTGGCTCGCATCGAGCTGAGGATCACCCGCAGTGCGAAATCGGTACCCAGGGTCGATGAGGCGGCCGGCCTGCTCCAGCACACCGAACAGGCGCTCACGCACGGAGTCTCCGGCTGTGCGGCCGGTGTGCTCGAGCTGGGCAGGCACGTCACCCACCTCCAGGACGAGCAGGGTGGCGAGGGACCTTTGGACCGTGGCGATCGGTGCGGGATCGTTGTGGTGGTCGCCGTCCACCCCCAGGTTCAGGAGCATCTGCGGCACGAGCGCGCCTGCCGCATCCGGGTGGGTGAACGCCAGGGCTTGTACGGCGGTTGCGGCAGCACGCCGATCCATCTCCAGCTCTCGTCCTGATTGAGGAGCGGGCCGCACACCGGGCGGGACCACTAGCGGCTCGGATGGTCGCGGGGCCGGCAACATGCTGGTGAGCACACGGGCCACGGCCTGAGGGGCCGCTCCGGCTGCCACGCGAAGAGCGCTGGCGTCTCCGGTTCCGCCCTCGTAGACCCCGAAGCGTCGGCTTTGAGGCTCAGCGAGGTACACCAGGGACCGAACCACTGGCTCGTCCACCTGGCCCCCATCTTGGAGACTCAGCAGGTCGGCCACGCAGCGGCCGGCCTCGACAACAGGGCTGCGCCGCAGAGTGGCCAGAGCGGCTCGCAGGACGTTCGCTGCGTGCTCGCGGCGGACGCGAGCCACGTGCCGCAGCGGCGTCAGCAGCTCCGGGACGTGGACGTCGGTCACCAGGTCCAGGGCCAACGCGATCACAGGGGTGCTGAAGGTCTCCGGCGCCCGCTCGGCCAGCGCAGTCAATCGCCGCAGTGCAGCGTCGCAGACCTCTCGGTCCCGTTCCGTTCCGGGCTCCTGGTCCAGGACGCCGATGTCGTCCAGAGCACTGGCCATCGCTGGATCCGACGACGCCTGCGCGCCCCGACGGTCCTCCGCACGCTGCTCCCACGCGCGGTGCCGCTTCGCCGTTTCCGCTCGTTCGGCCTCCTCAGCTCTCGCTGCGGCCTCTTTACGTTCGTCCATGACCGTGGCAAGGTTCGGCACGTCGCCCGTCGGACGGCGGTGGGAGCAGCCCACGCAATGCTGTTCGTAGAACTCCCCGACAATCCAGTCCAGGTTCGCGCTGGCACCGCCATGCGCCACGAGGCAGCTCACCTGCCGCGTGTTGATCGGCAGGCCGGTGGCGGCTTCGGCCATCCCCTGGCCGCCGAACTCGGTGAACGTCATGTTCAGACAGTGACGGCGGGCCATCTCCATCGTGACGGCATTCTTACGGCCGGTTCTCACCGCATCATCGAAAAATCGCTCTGCCTGGCTGCTCACTCCACTACTGTCTCAGGCACCACTGACAACGCCGCCCGACCATCGCTCATTGCAGACTTCACGTTTCACAGCGTCGCCCGAGGTCCTGACTGGCTTCGAAGGTGGTGTCGCTGTCGCCCTGCGGGATTTGGGCCAGGGTGAGGCCCGCCTGGCGCAGGGACAGTTGGCTGGCCCGGGAGCAGAAGGACGACGAGGCACATGTACAGCGCTCCACCCGCTACTTCGACGAGTTCCGCGCCCGCCAGAAGAAGACCATCGCCCTGTTCCCCAGCAACGGGGTGTCCCTCAAAGCCGCGGAGCAGCTGCTCCATCTGCCTGACAGCGTGGTCGAAGGGCCACAAGCCATAGCGAAGGGGCGCAAGCCCTTGCCGCCGATCGACGAGCTGCTCCTGGCCATGGGCGAGCCCTTCCCCCAGCCGGGCTGGCTACCGGCGGCGTTCTCACTGCTGAGTCAGGTCACCCACAGCACTCCCACCGGGCGCGCGCACATGGCCCGCTACGTCGACGGCACACTGAGGGCCCACGACATCTCCCCCGAGATGCTGGCCCTGGCCCTCGACGTCGCCTGCCTGGGCAGCGCCCGGCTCATCGGCCTGTCGTACCTGCTTTTGACCCGCGGTGACGACACGGCAAAACAGTACGCGCTCGGTCTTGAGGAACGAGCCCTTGCCGTGCACAACACGGCGCGCCTGGTCCACTGGCTCGACTGACTCCCACCTCCCAGGACGGCGCACCATAGGTCCTGCCGATCAGTTGTCGCACCAGGCGCTCATGCGGTCGGCGACGTGAGCGGTGTGGAGCGCAAGGGTGTCGCCGAGCGATCGTGCTTCATCTGCTGGGAAGTAGGCGTCCAGGAGGCCGTAGAGCGGTGCGTCAAGAGACAGTCGTTCCCGCACGTCCCGCGTGGGGCGGTAGTGGACCAGAGTGTTCCTGAAGCCTCTGTGAGCCTGAAGGATCAGGTTGCTCATCGGGGCGTCGAGGATGTCCTTCAGCAGCGCTCGGTCCGGCGGGCGGAGTTCGGCTCCGTACTGGTCGTCGAGCTTGCCGAGGCTGGAGAGGACGTGATGAAGGGTGATATAGCGCAGCTTGAACAGCGTTGTCGCCGAGGAGGGGTTGGTGTCGTCGGCGAGGAGGACGGCAACGGTGTTCAGTGCACAGGTCATGGCTGTCAGGGATGCCTTGGTCTCCTCTCGGAGGGCGGGATCGAAGCTTCGTCGGTAGTGCTTTTCGGCACGCACCTCGTTCTCGGTCAGGTCCGTTTTCTGCACGGCGTCGAGGGCGGTCTGCCCCTGCCAGGGCAGGCCCTCTGCCGCCGCGGCGATGTAACTGCCCTGTTCCACCGCGACGGCATGCAGTCTGGGGCCGAGCTCATCCTGGTTTTTGAAGGCCTGCGGGGGAAAGGCGAGGAAGAAGCTGGCTGTGTGCGAGGTCGAGACGAGTCTGCCGCGGAAGCGCCACAGGACGAGATCCTTCTCCAGCGGCCGGGCCAGTGGCAGCCAGGTGTTGTCGAGGAATTCCTGACGGTGTTCCTCGATGATGCGCCGGAAGTCGGCGCCGACGTCGTCCAATTCCTTGTACTTGTCGTCGTAGAGCTTGACCGAGTGCCGAGCGCGCTCGATGGCGGGCGCGCAGTCGTAGGCGAGGGCGTCCGCGAGGTCAGGATCGACGTGGCGAAGTGCCCGATGGGACTCGTGGATGATCAGGCACATGTAGTTGTGCATGCAGAAGATCGGGATGACAGCCTGGTCGGGGGCGGCCGTGACGTTGTGGGCGAAGCGTCGCAGGAACATGATGTCCTGTGCGATCAGTGCCAGGGCGATGTCGTTGCCGGGGGCTGTTGTCGTCATGGCCGTGCTCTTCTTCGGGTGCCGGGGAGGGTGTCGCCTCCTGTCGTACGGGACCGGTCCTGGCTTGGTGTCGGCAAGGGGCCGGGCAGGTGCTCACGGCATCGTGTCAGCAATCGGTGCCAGGACACATCAGGTTTTGGCTCCGCAGACCAGTGCGGACCCGGGCATGCAGCCGGCGGCGAACGACCGCAGAGCTGGGGGCGGCGGTGGCGGTGACCGCTGTGGTGAGGTTGGGACACCCTTTCGAGAAGGTGGCTGCAGTACGCGACCCCGACGATCCCAATGCACGCGGGGCGGAGATTTCGAGCTCGAGGAGGAAGACGAGGCCGAAGCAGCGGAGTCCGGCTCGGTGCATCGCCCGGTCAGCCTGCCTGTTCTGCGTCCTGCGGGACCAATTCCTCCCAGTCGTATAACTTCGTATAATGTATGCTATACGAAGTTATTACGAGACGAGGCCGAAGCAGCGGAGTCCGGCTCGGTGCATCGCCCGGTCAGCCTGCCTGTTCTGCGTCCTGCGGGACCAATTCCTCCCAGAGTGAGCGCTGCAGGGACCATTGGGGGGAGGGCTGATCTTCCGCTTCGATGCCGTATCGGTAGTCGGAAGCGTTCCGGTCCATGCATTGCACGTACGTGTTGAAGGACCCCGCATGCAGGGCTCTTCGAGCAAGACGTGCGTTCTCCTCGGCAGCTCCGAGTCTGAGTAGCGCTCTGGACAGGCCGCTCACATCGTGGTGGCCGTAGAAAAAGACCTTGTCTGCCAGGCCCGTCGCGGCGAGGCGGGCAGCTTCGGCCGGGCCGGCGGCCTCAACCAACGCGTCGATGAGCTCCTCAGCATCGGAGGCTTGGTGCACTGTGACGCATTCGGACGGCTTCCGGGCGAGGAGCAAGGTGAGTGCGCCAGTGGCGTCCTGCTTGTGCATCAGCCGCAGCAGCCCAGTGACCGTCTGCGGGCTCTGCAGTCTGACATGGGCGGCGAGGGTCCTGAGGAACTTCTTCCGCAGCTGATCACGTGCGAGGTCCTCCAGGGAGACGTCGAGCAGCGGTTCCCAGTCAGTCATCCGTGAGCCGACCCGCTGCACGAGCCGGCTGGCCTCCTCGTTTCTGCCCAGGGAGTCGTAGAGGTTGATGAGGTCCACGGTTTTCCTCAGGCTGTCGGCGCAGACCGTGTCCACAGGAGCTCGTGTCAGCAGAGTCTCGGTCTCATCCACAGCGTCAAGTGCGAGGAAGACCCGGTACAGCCGAGCCACCCCTGCTGCGTCCGCGTCTGTCAGCTCAACGTGAGCAGCCGGCGAGCGGGAGATGAGCCGACTCGCTGATTCTCTGTCGCCGACAGCGTGCAGGCTTTCGAGCAGCATGGCAACGCCCATGGGATCTGTCAGCTCGACGCTGGAGGCGGGGTCGCGTCCAAGGAGTGCCTCCAGCGCTTCCTCGTGCCATTCCGCAACCGAGATCGTATTGATCAGGCGGGCCGCGGTACGTGCGTCGTCGAGCCTCACGTGATGCACCGGGCCTTGCTCCAGAAGGGCATGGAATGCGTCAACGCCCGCCATGGTGCCTTCGTTCAGCATCGCTGTCAGGAAGTTTGCAACTGCGCCCCCGTCGGTGACGGGGACCTCTCTGACGGCTCGATTGATCACCGTATCAATGTGCCTACTCGCCTTCACTTGGTCCAGTGCCGTCAGCAGGCGACCGAAGTCCCAGGGATCGTTCGCGGGAGCAAGCTTTGCGATGCGTCCGGCGAGAGCATCCGCTGCCTGATGGGCGCCTGCCTCGCCGAACAATTCAAGGAGGATGATCGCGTCGTAGGTGTCATCGTACGGCGCGCCGTAGATGTCGTAGGGCTCTTTTAGTCGGACCCTGGAAGCCGGGTCACGGCGCAGCAGAGTCTGCACGGCCTGGTGTGCGTCGGCTTCCAGGAGGGTTTCCAACAGGTAGGCGACGGCGCCGACATGCTCGAACGGTACGGACCGGGCTGCCCGCTCGGCCAGCTCGGAGACGGCTTGGGGCCTGTCGAGGGCCTTTAAGCTGTTCACCAGCAATGCGACGTAGTAGGGATTGTCGGCGGCCGCATGCAGCTCGGGTTCGCGCCGCAAGACGATGTCGATCGTATCCGAACGGCCTGCTTCCTTCAGCTCGTCCAGGAGGAAACTGACCGCATAGGGGTCAGTGAGCGGGGCCCTACGTGCGATCCAAGAGTAGGCGTGTGCCTCAGCTTCGAGCTGGCGGATGAAGGTCACCAGCCATCCGGCTGCGAAGGGCGCCTGCAGGATGAGTGCCTTGTGGCAGGTCAGGACTGCGCGCTTGCGCAGGCCCCTGCTCCATGCATGGCGGGCGAGCCAGGTCAAGCCTGCGCCGTCCGTCACATGATGCTCGGCGGCCTCCCAGAAGGTGGTGGGAAGCGGCTGGTCTGCTTGTTTCTCGCCCGCGTGCTGCTCCAGGTAGTCGGCCAGGGCGTAGACGCCGGGTGTGGCTCCCATGCCGGTGGGGAGCGCGACGGGCTGCAGGGCGCTGGCGACGCCTTTGATCGGCTGCTCACAGTACTGTGTGGCGCGCTCGAACCAGTCTGCCGGCGCTGCGGCCCGTTGATGGTCCGTGAGGTAGCCGGGGGCGGCGTCGTGGAGGAAGGCTTTCGTCAGGGGGGTGCGCACGCCCAGGCGTCGGGCGTCGATGGCTGCGGTCAGGACGGCTCGCCCGTAGGGACAGCGGGCGTGCTCCCAGCGATCGAGGAGGTCGGGGCCAGCGGCGAGTGTCTGGGCGACGGCTCCTGGCTCGGAGACTGTTTCCAGAGCGGCGCGCAGTGCGGAGTCGTGCTGTGCAAGGTCGTTGAGCTCCTCCAACGGACGGCCGTGGAAGCGGTTGGGGACGTCGATCGCAGAAAAGGGGCGCAGCAGCTCGCGTGTCTGCGGGTGTAGATCGTTTCCGGACGGGTCTGGGGTGACGAGGGCGTCGTAGTGCTGGGGCCACATGGTGGCTATCAGCAGTCCTGGACCTGGCCGTTCCAGGAGGTGCCGCAGGGCAGCCGCGGCGCTTTCACCGGCGGGCTCGTTGAACAGATGGTGGGCATCATCGAGCCACAGCACCGTCTGGCTGGACACGGTCTGTGCGTCGACAAGCGCGACCACGGCTTCGGCAGTCTTGGGGTGGATCAGCCGCCAGTGGGGCACAACGGCGCGGACGGCTTCGTAGGCGGTTCGCGTCTTGCCTGTGCAAGATGATCCGCGCACGACCAGGAACTCGAACTGGCTGCCGTCAGCGATCCTTTCAAGCCGTCGCCGGATCTCTGTGTCGTGAGGGCGAGGGACGTAGGCCGGCAGCACGAATCCGGGGGCTGGAAGGCGCTGGCCCGGACTCGGCGCTGCGGGGTGCACTCCCAGGAGCTGCGCGCCCCAGTCAGCTGTGGCCTTGCTCGTCTCGGGCACAGGGGTTGAGATCCGCTGGCGGGCAGTGGGCGGGTGACGGCAGAAGAGGGTTGCCCATGACGGCCCGAAGAACTCCTCGACGATATCCGGAAGGTCTCTCAGGCTTTCAGAGACCGATTCCAGGCCCCACGGGATGAAGGTGATGCTTGCTTCATCCAGCCGGTCGGCCTGTCTGAGGATCTCTTCGGCGAGCTGGGTCGGTTTCAGGGAGTGGGTGGTGGCGTATATGAAGGTCGCACTGCGCGCGGCCCATGTGCCGGCCAGGAAGTCATCGACCGCGGCCCGTATTTTCGCGGGTGTCAGATCCTTGACCCTGCGCGACTGGAGGGTCAGGTACCGGCGGCTGCTGCTGGACGCGTCGGAAGCGGCGAGGCGTACATAAAGGTCGATGCCGTCCTGCCTCTGGCCAGGAGTTCCGTACTGCTGCGCGTACTCGGCGGTACCTGAGCGCTCTGCCAGCCGCAAGAACAGCCGCTCCGTGTTTTGCCAGGTCACCTCGGCCAGCGGCAGAACTTCCGGAGACGTCTCAACCGGAGGCGGCACTGTTGTCGCCGTGGGGGCGTCGGTGAGACACGCTGGGAGGCGGCCGTCGTACCGGCCCTCGTCATCAAGCTCCACGCGCCCATCGTGACACGCGGCTATGACAGTTAGAGCCGCAGCTGGCCGCGGTGCAGTGATAGCACGGAGACGCCGACACCGCTTTCCCACCCCAGTCGGGAAGCATCCGAAGACGACAGCGGGCAGCACACGTGGCGTGCGCCCTGCCGTGATTTGCCTGATGGCCTGTGCTCCCGCGGTTTGAGGGCAGAGCGATCGCTGTGCCGGGCCAGTTTAGAAGGAGCTGCCAGACGGTGCAGGCCATACTCTCCGCAAGCGCGCTCGTCGACAACGGCGTCGAGGTGACGGGGCCCGGAACGCCGGAACCCACCCGGCCCTGTCAGTGGGGGACGCAAGAATGACGACGGCGCCGCAGTCCTGATGGGGTCCCGCGTCATACGGGTGCCTTTGTTGCGTACCGCACTCGCAGGCCAGCAGTCGTGCCGCGCGCATCCTCGCTGCTGCGCTGACTTCTGCCTTGCCTAATGCCCTTGTCCTGTCACGTCTTGTGCCGGAGGTTCCGCCATCATGGCCAGCATGCTTGTCAACCCGTTTCGTACCCGGCTCGCCCCCACGCCGCCCGGCGACGGTGAGAGCGAGGGCGAAGGGCCGCCGCAGGCAGGTGATTTCACTCATCGAGCGGCGGTACTGGTCCGGGTGCCTGCCGGCGCGGAGGAAGCCACCGCCCGTGAGCAGTGGGCGCGCTGCGGTCTGTTGTTCTCTCCTCTGGAAGCGGCCGGGGATGACGCGACGGCGGTGTACTGGGTGGAAGTGCGGCTGCAGGGAAGCCGCTGGGGTGCATTGACCGAGGCAGAGCGCCGGGTCACGGCGGCCCTGGCCGGCCGGGTGAGCGCGCACATCGCTGACGCGACCCTGCTGGAACCGGAAGTCACACCAACGGTCGTCAGTACCTGGCACATGCACCGCAAGACCGACTGGGGGCCGGGCTGGTGGCGCAGCAGGGCAGCACAGCTGTGGGTGCAGGTCGGGGCGGCGGATGTGCACCGCCGGGTGCGCCTGGACGGTCCGGGCACGAGGGAGGAAGCACTGGCGGCCCTGCAACGCGGGCCGGACGTGGGCGGAGTGCACTTTGACGAGAACCTGCATGACGTGCGGCCCGGTATCGCGTCGGCCCACGCTGTGCGCCCACAGGATCCGGCTCCCTGGCAGACCCGGGCGCTGGGACTTCCGGGCATGGCGGTGGGGGCCGTCGCGATGCTGTTCGGCTGGATGCTGGCGGGACTGGGCCTTGGGTGGCAGATGGCACTGGCGCCGCTGCTGGTCGTGGGGGCATGGTGGGTGGGCCCGTGGCTGGCCGACCGGGAACGGCACTCGGGGGTAGTCGTCTGGCTGTGCGGGTTGGCCGTGGTCGGCGGTACGGGGCTGTGCGGGTTTATGATCCGGGTGGTCTCGGCGGCACTGGGCGGTGTCGATGTGCGGGCGGTGGTGGTGATGCTGTGCGGGCTGCCGGTGCTGCGCGGCTGCCTGTACGCGTTGCGCCAGAGCTGGTTCTCCCGCAACGCCGCCACCGTGCTGTCGCTCGCCGTCCTGCCCCTGGCGTGGGTGCTGCCTTGGATGGGACGACTGGTGCAGGGCATCTACCTGACCGTATGCCTGGGCATCCCGCTGTCGGCCGTCAACGTCGATGCCCTGTGGACGTATCTCGCTGGGGTGAAGCCGACCGCCCTGTGCATTGCCGCCCTGTTGTGCGGGCTGGCAGCGCTCGGCTGGTGCCGGCACTTCTACTGGATCACCGGCTCAAGGACGTATTACCTGGCCGTCTTCGGCACCTTCACCGTGGTGATGATGGTGGTGGCCGTGCTCGTCGGTCTGTCTTCGGCCACCAACGGGGCCGATCGCACCGTCGCGCAGGCCGTGGCCGGACAGGACCCTTCACCGTTCTTCGGGATAAGCGCGCGGCGGGTCTGTGTGCGCCCGCTCGATGCGGCCAACACAGCAGTGCAGCCCGGTCCGTTGCCCACCGGCTATCCGGTCGTCGCGTTCGACGTCACCGGCGACGAGACCTGGCTGTGGGACTACCGGCGGGCCACGGCCTCGGCCGACCTCGCCAAGGGAGCACTGCGCGTACGCACCGATCAGGTCGTCACCCAGCCTGCCGCCCGCGGGGCCCGCACCTGTCCCCCGCTCTAGAGCTCTCGAAAGGTCGCTCGCAGGGCCTGGGCCGGGCCGGTCTGAGGGTGCTCCGTGATGACTTCGCGCAGCACCTGTCCGAACGTAGATACGCCGGACGTCCGCGACGTGCCTCCCTCGAAGCCGCCGTGCCCGGAACCGCAGAATGCAAGGATGGTCTGCGCGTGGATGGCAGGGTGTGGCTCGGGTTCGGCGACACTCAAGGCATGACGCCGACGGCTCATGCCCCACGAGAACCGTTACATCCGGCCAGGCTGCACTGGGGACCGAGTGGCACGGTCGGGTGTCTCTTGGGACCTTTCGCCGGCCGCGTCCGGCCCTGGGCCGGACCCGACGGGCAGGACGGCGGTTGTGGTCAGGGCCGAGGACGGCTGCGCGCTTCGAGGCGTGGTCGTGCCCGTTGTCAGCTGCGGGTTTATCGGCTGCCTCGTCGGCGCGGTGCGCGCCGGCTTGCTGCTCGGACCCACTCAGCGGCTTGCGCGATGGGCACGACGGGAACGTCTGACTGCAGGACGCGAGAGGCCATCAGGTCCCGGCTGGTGACGATGACGGGGATGACGGACCATCCTCGTGTGTCGCTGCTGCGCGTGTAGTGGTGGAGGGTTGCTGCCAGGTGGCTCTGGATCCACTGGGCCCGACGGCTGATCTTGTATCGGGCGCTTTTGTCCCCCCGGATCAAATGGTCTGCTTCATTGGCCAGTTCGGCGGGGTTGCGCGCCATCTCGAAGTCCTTGGCCTCGGCCACGAAGATCTTCTTGTGGGTGAGGCTGATCCCCAAGGCGTCGATGTCGCCGAGGTCGTGTCCGTCCGCGGTCAGTCTGCGGCCTTGGATTTTGGCGACGCCGCAGGCGGTGATCTGGCAGCCAGCTTGTTCGAGCGCAGTTTCGACCTGGCGCTCAAAGTCCTTGTTGTTGTCCTGTCTGATCGAGCCCAGCAGGGTTTTCATCGCCGGGGAGGTGGCTCTGAGCCTGCCGGAGTACACCAGGTTGCTCCAGTAGCCGCCGGTGGACCACAGGTGCCGTGGTGCCCATGCCAGGCAGGCTGTGTTGTCCTGCTGCACCTGGATGAGGGGTCTGCGGGCGTAGGACCATTCGCGGTTGAAGCGCCAGGGCCAGGCATCTGCCTTGACGGAGAGGAAGTCGGCTCGGGGCTGCAGGCTCAGCCGATGTAGGAAGGCTGTGGTCTTTCCCTCCGGCCAGCCGAGGGCGACGTTCAGGTGCTGTGTGACATCGGCAGCGGGCAACAGGACGGACTCGCTGGGGCTGTGCTCCTCTCCGAGAGCGATCAGGGTGCCGATTCCGTCGGCTAGTTCGGTCAGAGTGAAACCGAATTCGGCTCTCATGGCCTCCTCTACCGCGGAGGAGGGGGGCTTGGCCTGCGATCCGGCCGGGGTGATCGTGCGGGCGGCTGCTCCCTGCAGGGCGGCTTCGGCTCGGGCCAGCGCCAGGGTGTTGGTACCCGTCTCGAAGCGGTCCGCCCGGGACACGCCCAGCCGCCCGGAGTCGAGCAGAGACAGACTGACGTCGGAGAATTCGTGGCGGATTGCATCGGAGAGCATGGCTCGGCTGATCAGGTCTGCGGCGAGGGCCATGAGGCGGTCATACCTGTCCAGCGTCAGCTGCTGCTGACCGGACGGGGGGACGGCTGCCGCGTACTCGATGAGGAACCGGCTTGCCTGGGCGGCCTCGACCCGCCGCCGGCTGATGCGGGCGAGTTCCTGTGCAGTCTGGCTGGTGGGGCCGAAACAGGCGATCCGGGCGGGCATGCCTTGGTGGCTGACGGCGTCGGCGTTCAGGAGGGCTTCGTGTCGCTGCAGGAGCTGCCGGAGCAGCCCGTCGGGGCTGAGTTCGGCGAATGCGCTCTGCAGGAGATGGAAGTAGTAGGCGACTACTTGGTTGAGGACGCGCAGACGCTGATCCGGAGCGATGGCTCCCGGGGGCGTTCCTTCGCGGGTGAGCCACTGCCCGAGTTCGTCCAGGACAACCGCAGACACAGCGGGCTGGACCAGCCGGGGCGCCGGCAGGGAGTCCGACCGCAGCAGCAACTCCTGGCCGCTGACAACGTGCAGCATCTTCTTTGGGCCCAGCGGCGCAATGCGGTCGATCAAGTCGTCGAGGTCAGTGGTGGTGTCCGCGGCCACGGCGGCCGCCGTGGCCAGGGCGTGGATCAGGATGCGCTCAGCATCGTTGGTTTCCTGCTGCAGCAACGGCCAGCCAGCCGCGGACAGCTCGAGTCGGAGCTGGCCCGGTGCGCTGGTGTCGGCGCGGATCCACGGGTCGGTGCCGTCGGTGGCTTCCTTGCCGGCCAGGGCGGCTGCCCACGCTCGCGGGTCGTAGGACATTTCTACCGTGAGGCTGTCCTGGTCACCGGCCGCTGCCGGCAGCAGGCCCGGTGCGGCACCGGCAAGCTGCCAGATCCAGTAGGCGGCGGCCTCCAGGAAACAATCGTGAAGGGCGGCCGGAGCAGAAGTACTAACGCCTGGCGCGGTTACCCATACCTGGAGGCCCGCGAGCTCGACGAGCAGGTCCTGTCCACCCGTCGGTGCTTCGGTCCGATAGACCGGGGCCGTGTCCGTTCCGTAGACGGCGCTCACGGCTACGAGAGTGTCCCGGTCGGGGTGGGACACCTCGTGCCGGTCGAAGCGCCTGTGGGCCTCAGTACGCAGGTGTGTGCTGAAGTCGGAGTCGACGGTCACCAGTGTGGGCCGGCGCTCGTCCGTCAGGTAGAAGCTGTGGGCGTGCTCACGGTAGAGGCCGTAGGTGTCTAGCGTGCCAAACGAGATGACCTGAACGTCGTTCCGGAGAGCAGTTTCTGCCTGGGCAAACCGCCACAGGAACAGGGGATCACCACCGTCCAGATCGGCCATCACCTGCAGGTCGTCGGCAGTGAGCATCAAAAAGGGTCCGGGGCGGCGCAGGCTGCCGATGCCGAGAAACATGGTGCGGCCGAAGCTCTGGTTGATGACCATGCGCAGGGTGCGGGCATCGTGCTCGGTCGGTGTTCCGGGTGGGTCCAGCAGGTCCTGCACTCGCTGGCTGTGCGTTTGTGCGTTCCACTGTCCGTAGGGGTCTTCGTCGTCGTAGTCGGACAGGTCGTCCGTGATCACAAGGAGGTCGAGGAATGTGTCGTCGGCAACGGTGAACAGGCGGCGGCTGAGGGGTACGTCGCTGATGTGGGACTCGGGTCCTGCCGGACGGGCCCCGCACTGAGTGAGAGTGCGGGTGGTTGTCTGGAGTACTTCGCGGCGCAGCAGTTCTGCGAACTGGGGGCGGCAGTTGTAGGCGCCGGCGAGGACAAACAGCCGGTGGCGGAGAGCGGCGGCAAGTTCACCGGGATTAGCGACGATCATGCTGTCGTTGGCTGCCAGAACTGGTGTGAGGACGAGCGTTTCGTCCGGACCCGGCCCGGGCGGAAACGTGTGCTGGCCCGGTCGCACGGTGAGAGGAGCAAGCAGCTCGGCAACGGGGCCGGGGACGAGCTGTTGCCACGTCGGCTTGTCGAAGATCACCGCCTCGCACAGTCGGCTAAGTTCGCCTGCACCGGGCACGAAGACTTCCGTGTTCCGGGCCGTGGGCACCACGATGCCGCGGCCCAGGCCAGCACGGATGAGGACCGTGTGGCTCAATCGGAGCACGGCATCGGTGAGCGCGTGCGCTTCCTGCCGGAACGCACCGGGCAGCGTTGTCCCGTTCGGGCCGAAAATGCTGCGCAGTAGCAGGTTCAGAGTGAAAGCCGAGCGGGACGTCAATCCTTGCGCAACAAGGTACGGTCCGCCGTGGAAAGCTATTTCAGCGGTGTAGAGATCGTCGTAGGGGTCTTCCTGGGCGCGGACGTCGAGGCCTGCGATCACAGGGTTTTTGAGCAAAGTCCGCAGCCTGCTGGGAGATAGACGAGGAGCCTCGGGCCTGTGCGGCAGGCAGGCGGCCACGCCGGCCAGGCGCTGTAGACGGACCAGCCGGGGAACGTTCTGCGGAATGAGCTGCAACGCAGCCGCGGCCCGGGCAAGCGACGGACCGTCCACCGCACTCCAGGGTGTGCCGTCCAGCGCCGTCTGCGACATGTCATCTCCGTTCCGCGAGCCGGAGCATCCCGCACCACCCGCCCGTCACTCACACCACGTACCACCTGTCACCGTAGCCAGTGGGACTGGCATCCGGCCGCACCGAGCCGGTGGTCACAGACGTAGGGCTGCCCATCGGGCCTCATGGAGTGGGCGAACCGTCTGATCGCCTCTCAGCCGATGTCACTGCTGTTGGGCCGGCGTCACCCACATGGGACGGCTGCGCAGGGCAGGGCCAGGCGTTCCGGCCGGGACTCCGCCTTCAGCTCTGCCTGAAGTCACGGGCTAGGAGCTTCATCTCCTCGCCCCAGATGGTCACGTTGTCGCCTTTGCGTCCGAACTCCTCTCGGGCCAGGCGGTAGAAACCCGCTCCGGGCTCCCCCTTCTCCTTCAGCACCACCATGGCGGAGAGCATCGCCTTCTCGCGATCCGGGCTCTCCTGGTGGGAGACGTCGGCCAAGAGATGATCCATCTCCACGCTGTGTGCCGGGACGGTGTGGCCCTCGTCCTCCAGGAGTTTGCTCAGCTGCCCGTACTGGATCGGCCAGTCCCCGTTGCGGGCCCGCTCCAGCAGGATCTCCGCCATGGCCTCCTGGGCCGCCTCGTACTCCGATGTTCCTCGCCTCACGGCCTCCCCCTCAACATCGACAGGGACGCCAGAGTAGTGAGATCGAGCCGCCTGTTCACCTCCGCCCGCTCCTGACGGGATCGCAGCACGACAGCCATTAACGCGCCGAACACGCCGGCCAACCCATCAATGGCCTCCTCAATGCCCCGAGCTGCTGGGACGGCTGGTGAGAAGAATCAACCTTCGCTGCGATAGGTCAAGAGCTACGGCTCCTCGTCCGCTTCACCTCAGGGCTCAGCACGGCAGCATAGGAAGTGCCATCGATCTGTCCGGCAGGATGTCACTTGACGCCACCGACTGATGCCAGCAGCCGCCACCAAGGGCATCACACTCAACCGCAGGTCAGGGGATCTATCTCCGACACCCGACACTGACTCAGTGACGACATCTCCTCAGTGGCACTGCAACGGCACTTCACAGCCTCACGCACGGCATCCGCGTCGGGCGGAGGACCGGCGTGGCCGGACGGCAGACCGAGGGGGTGGAGAGCCGCGGCGGCCAGCGTGCGCACGGCCGGGATGTCCAGCATCAGCATGGCCGCGACACGCTGCAGATCCTCGGTGATCTGCTCGACCGTGCGGTCCAGGCCGTATCCCAGATCGTGGAGCAGCTCGCGCAGGTCGGCGGCCTCGGGCTCGCCGGCCTGCGCGCGGCGGAACACGGCCAGGACCTGCCAGAGGTAGTCCAGCTCCCATCCGGACAGGAACAGCACCCTGACGGTCTCGCCCTCGCCGTCGGCCAGCTCTTCCGTCTCGGCGGCCAGGCGGCCGATGACGGAAGCCGCTCCCTCCAGGACGCCGACGGACAGCACGAACCGGTCCCCGTCGAACCGGGCGGAGGCGACTGCGGCGGCTCTGGCGATGACACGGAGCACCCCTTCCGGCTCATCGAGCGTCTGCCCGCCTGACATCGTCACCCCGCCGGAGCTCCCCGGAGCCCCGGCGGGGCCCAGCTCGCCGAGCAGGAGGCCACACGCGAGGACGGCACGATCGCCGCCACGCCCTTTCAAGTCCGCTCGCTAGCAGGCGGCCACGGAGTCCCGGGCGGTGAGCTGACCGCGCTCCGCTCACGACCGACAAGCTCCCCACCGACCAGGTCCGACCACGTCGGCCGTCCATAGGCGAGCCGAGCGGAGCGGTGCGGTGGCCGGTCCCGGGATCGGCCACCGCACCGTCACCCCGGCGCACCACACCTACCGCCAGGCCATCGCGCCGCAGACACCGGAGCCACCGGGGCCCTGGGCGCCGAGCGCTGCCTCGCCACCCGTAGCGCGCAGAGACCGAGCCGGCGGTCCGCTGCCGTCCCGCCTGAGTGACAATCGACGCGAACCTGCGCCTGGAAGCCGCTGCCGGGCACACGCCGGGCAACTCCGTGCTGACTCTCACCTCCGGCACGGACCGCGCGGTGTTCGTCGGCGACATGCTGCACAGCCCGGTGCAGATCCTGGAGCCGGACGTCAACAGCTGCTTCTGCGAGGACCCGGCCGAAGCCCGCGCCACCCGCCGCAGGGTGCTGGGCTGGGCGGCCGACAACCATGCCCTGCTGATCCCGGCCCACCTCGGCGGCCACGGCGCCGCCGAAGTCGTACGCGAGGGGAGCGCCTTCGCCATCAAGGGCTGGGCGCCCTTCACCCCGGACACCGAGTACCCCGAGTACGCCGCGCAGGGCTGAAGTACGCGGGAAGGGAACCAGGGATGAGCCACCACTCCGGTCCCGTCGTGACCACCGCGCAGGGAGCCGTCCGCGGTCGGCGCCAGGACGAGGGCACCGCCGCCTTCCTGAACATCCCCTACGCCGCTCCTCCTCTGGGCGCCGGCCGGTTCGCGCCGCCGCAGCCGCACGAGCCGTGGGACGGCGTACGGGAGGCCACCGCGCCCGGCCCCAACGCGCCACAGGCCGAGCGCAGGCTCGGCAGCCTCGACATGGTCCCCTACTTCGGCACCGGCTGGAGCCGCGGCGGGGACTACCTCACCGTCAACGTGTGGGCGCCCGCTGCCGCACAGGGCGGCCTGCCGGTCATGGTGTTCGTGCACGGCGGCGGATTCGTCGCGGGCTCGGCACGGGCCGCGCTGTACGACGGCTCCGCCTTCGCCCGTGACGGCGTCGTCCTCGTCACCCTCAGCTACCGGCTCAGCATCGCCGGTTTCCTCGACCTGCCCGGGGCACCCGCCAACCGCGCCACCTCGGCCGCCGAGGACGTGGACGACACGGCGGCCCGCTCGCACCCCGACCCGGCGCGGCTCGTCGAGACGTACCGCAGGACACGCCCCAAGGCGTCCTACGGCGCACTGCGCTCCGCCATCATGACCGACGCGTTGTTCGGCGCGGACAGCAGGGCCCTGGCCACCGCTCACTCCAGCCACACCGGATCCTCGACCTTGGCCTACGAGTTCGCCTGGCGCTCGCATGCCCTGGACAGAGAACTTGGCGCCGCGCACGCGGTCGAGCTGCCCTTCGTCTTCGACCTCACCCACCTGCCGCAGCTGCTCGGCCCCGCCGCTCTGCTCGGCCCCGACAAGCCCCCCGCAGATCTCGCGGCCCGCATGCACGAGACCTGGATCCGGTTCGCCGCCACCGGCGACCCCGGCTGGGACCCGTACGACACCGAACGCAGGGCCACGATGCGCATCGACGCCGAGTGGTCCCAGGTCGACGACCCCCGCGGCGAGGAACGACAGGTCTGGAGCTGATGCCCGTACGAGTCGTCTCGGGCGGTGCCGGCGCACTATCGGCAATCGTCTGGTGCGGGGGCAGCGGTTGCCGTAGGGTGCCGGGCGGCCTCTATGGGAGCGCTCCCATAAAGTTCCACGCAATCCCTCCGACATCACCCGATGGAGACCTTCGCATGCGCTCTTCCCTCCCCTCCGTCCGGCGGCTGCCCCGGCTGCTCGCCGCCGTCGCCCTGGCCGGCGTCACGGTGGTGGCCGCCACCGGCGGCGCTCCGGCCCACGACCGCCACGGCGGCCGGCCGATTGGCGGCTGCGCCCCCGACCCGGCGTTACTGTTCTGCGAGGACTTCGAGGAGCTGCCGCGCGGCGCGGGCACCAGCCTGGACTGGGGCGTGGACACCCGGAACGGCGCGCTGTCCGTCGAACGCGAGCGGGGCCGCGGACACGGCGGGAAGCGCGGCGCGGACCAAGTGCTCCGGGTGCGTACCGAGGGCAACGGATACGCGTTCCTGGAGGTCGACGAGTTCTCCGCCCCGGACAACAGCTTCTTCGGCCGGATGCGGGTGAAGGTCGACGCCTTCCCCACCGCTCCGGACTGGGCCCACTTCACCCTGGTGGAAGCCGCCGGCCGGGGCGACGGCAGCGTGGTCCGACCGATCGGCGGCCAGTACGTACCAACCGTCGGCGACGGGGTGCAGCTGTGGGGCATCGGCTCCGACGGCGGCCCCACGGGCGACTGGACCGACTGGCGCGAGTCCGCCCCGGCCGAACCGGGGAAGTGGACGTGCCTGGAGTGGGAGATGGACGCCTCGGACAACCGCGTGGCAGTGTGGATCGACGGCGAGCCCCAGCCCGACATGACCGTCACCACCACCCGGCACGGCGGCAATCCGGTGGACTTCGTCTTCCCCACCTTCGACACCGTCCGCATCGGCTGGCAGCTCTACCAAGGCAATCCCACCCCGAACTCCTACGACCTGCGCCTGGACGACCTGGCGCTGTCCACGGAGCGCGTCGGATGCGGCCGCTGACCGGCACCACGGGCCGGCGCCCGCTCAGGGCACCGGCCGGCGGAGGCTGACGGCGAGCAGGGCGATGGCGGCCAGTACCACGGCGGCCGCCACCGCCATCGCCCGGCCCGGCGGGCAGCGCGGGCATCGCCGGACCAGGCGAGGGAGAACAGGCCGCCGGGCACGTGGACGGCGACGACGGCCGCCGCGCAGGGCAGGTCGTGGCCGGCGGTGCGGGCGGGGTCGGCGGCGTAGTGGTCGTACTCGGCGCGCAGCCCGGCCATCGCATCCGCGCTTCCGGCAGCGGCGCGGGCCAGACGGCGCGCGGCGGTACGGGTCCAGGAGCGGACAGCCGGGGTGTCACCGACACCGTCGAGCAGGGCGTAGGCGCGGGTGCCGTCCGGCATCGTGCACACGGCAGTGGCGTCGCACTGGAAGACCCGGTCACCAGGCCGCTGTGCGGTGGCGTACGACGTCACGGCCAGATCCTCGTCCACGTCCTCGCGCATGCGACAAACCTCCCAGAACACGGGCTCCGGGCGGAGCGCTTCGCGAGGGCGCCCGTGCCCGGGCGGGTGAATCCTTCCTCGCGCACGCGGACGCAGCCCTGCAGTACGGCCAACTTGCCTACTTTCAAAACGAATTGACAGCTCTGTAAGGTTCTGTCATGTTCTGTCCGCCGTTTCCGGTGAACGGGCGAGAGGTGATCTCATGCGACGAACCGAGTACGACGCGGGCCAGGCGGCCAAGCGCCTGAAGGTGCCCGCAGCGGCCTTCCGGTGGGCCCGGCACACCGGCCTCGTCCCCGCCCCCGACATGCCGCCGTCCCGCTGGTCCCGGGCCGCCGCGGAGGCGATGGACACCGACGCCATCCAGGCCGCCATGCCCTCCCCGCCGATTTCCGGCGGCGCGGCGGCGGACCGGATCGCCGACGCGCTCGGCACCCCGAACGTGATCGGTGAGAAGGCGGCCGTGACGGCGTTCGTGGTGCGCCGGTTCGTCGACCGCGGCCTCCTGGCCGACCTGAGCGCGAACCCGGACGGGACGCTGCACCACCCCGACCAGGTCGACCAGGTCTGCCGCCGCAAGGACCTGGCCGACCTGGTCGCCGCCGACACCCCGCTCGGCCCCGAGCAGGCCGCCGCCCGCCTTCGGGTCCGCCGTGCCGACTTCGACCACATGGTCCGCCTCGGCTGGGTCCGCTCCCCGCAGTCGATCGAGGTCCGCTTCGGCACCAGCCGGGCCGGGGCCGTCGACGTCGCGCTCTACACCACCGCCTCCGTCGACGCGATCCCCGCCGCACACCCCGAGGTCGACTGGGAGCAGTTGCGCGCGGTGGAGAAAGGCCGGCGCTCTCCGCTCGCGTCGCTGCGCCCGGCACCGGCACCCGCCTGAGCGCCCCCGCGCTGGAACAGCACTACGAGGGTGTTCCCCCGCCCGCCGCGTCCCAGCCGTCCAGAAAGGCGGCCAGGGCGCGGCGTTGCTCTTCCTCGCGGGCGATCTGCCGGGCGAGGACGTCGCGGTCGACGTACGAGTCGACGGCGGCGAGGACCAGGCGCCGGAGTTCGGCCGGCTCCAGCGCCTCCACCTCCCACTGCACGGGGTGTCGGGGGTCGAAGCCGTGGCGGCGGGCGAAGGCCGGCCACCTCGGATCGCCGTGCTTGCCCTCGGTCGAGGGCAGCTCGTAGGCGCGTACCTGCTCGTAGGTCAGCAGGACTGGGGAAGAGTCGGTATTCCAACCCTGCGCTATTCACCTCGGCGGGTGGAAAGCGAAGAGCAGGTCCTGATCACCTGCGGGTAGTCTCCGGCCATGACCGGTGACTGGCGTATGGACCGGATCGGGGCTGCTCTGCGGGGCCACAATCCGACTGTTCTGCGGCGGCTTGAGTCTGGCTTCGCCGTGATCGGCGACGTTCAGTTCCTGCCCGGATACTCGGTTCTCCTCGCGGACGAGCCAGATGTACAACGGCTATCTGACCTGCCTAGAGCCAAGCGACTGTCGTTTCTGTCCGATATGGACCAGCTCGGAGAAGCGGTTGAGCGGGCCTGCCAGCGGCTGGACTCCGACTTCCGCCGGGTCAACCTGGAGATCCTCGGCAATACAGACCCGTTCTTGCATGCCCATGTCTGGCCGCGGTTCGAATGGGAGCCGGCCGAGCTAGTGGGCAAGCCGGTGTGGCTGTATCCGCGTGACCGGTGGAGTGACGAGCGGTTCGGGCTCGGCCCGCAACATGATGTGCTGCGGGATGCGATCAGCAGTGAACTGGACCGTTTGACCCTCAGCTAACGACCTTGGGAGCGATTGGCCTGGGAAGGCGGGTGCCTGGATCGGTGGACGGGTGCGCATGAGATCTTTCTTTTCATGAGTACACCACCAGACGGATTGCCTATCTACCGAGTCTTGACCGGCCCGGACGACGTCGCGTTCTGCCATCGTGTGAGCGAAGCGATAGCTCTTGGCTACGAACTGCACGAGGGCCCTGCGGTCACTTTCAACGGTGAGAGGGTCATCGTCGCCCAAGCGGTGGTATGGCCAGCACAGCCGTAGGACTTATGGTCGCGGTCTGCCCGTGACACGAGAAGGACCGTACGGGTTAGGCGAGTGTGACGCTTGTCTGGGCCCGTGCGGCCTGTTCCCACCCTGCCCTGTCCGGGGTCTCCCGTGCGCACTTCGGCGAGTTACTCGAAGAACTTGCTCCGCGTTGGGAGGCTGCACGTGAGTCGGCGCTGCGCCAGCGGCGCGGCCAGGACCGGCGTCGGGCGGCAGGTGCCGGACCGAAGCGGCGGCTGGTCTTCGTGGACCGACTGCTGGTTACGCTGGTGCACCTGCGGCTCGGTTTGCCGCATGCGGCGCTCGCCGAGCTGTACGTGGTGGACCGCTCCACCATCTCGAACGCGGTCCGCGAGGTCCGGCCGCTGTTGGCGGCCCGCGGCTTCGCCGTCCCCGACCGCCCCGGCATCCGGTTGCGCACGCTGGAAGACCTGTTCGCCGACGCCGACGCCGAGGGCGTCGAGCTGCGGATCGACGGCACCGAGGTCCAGGTCCGCCGTCCGAAAGCCGGCCGTCCGGGCCGCAAGGCCTTCGTGTCCGGCAAGAAGAAGCAGAACACGATCAAGACCACGACCTTCAGCGACGGCCAGGGCCGCACCCTGTTCAGCGGTGTGGTCCGGCCCGGCCGCATGCACGACCAGACCGCCGTGCGCAGCGAGGGTATCGCCGAACAGCTCCGCCAGTACCCCGATGTCAAGGCCACGGTCGACGAGGGCTACCGCGGGCTGGCCAACGAGTTTCCTGACCAGGTCGACGCCCCACCGAAGAAGCCCAAGGACGACGCCCCGCTGGGCGAGCACCACGCATGGCGCGAGCGACGTCGCCATCAGTCCTCGGCACGGATCCATGTCGAGCACACCAACGCCGAGTACAAACAGTGGCGGCCCCTGCAGCGGTTCACCGGCCGCCGCGAGACCTACACGGAAACCCACCTCGCCATCGCCGGACTGGTCTCCGACCGCTCCGCCCGCAGGCCCACGCGACGCAAGCCCGGCACCGAACTCGTCGCCCCGGCCCGTCCCCTGGTCGTCGTCCGGCTCCGGTGGCGCGGCGGCCTGGCGCCGGGCGGCTTCGGCGGCGGCTGCCTCGCGGGCGACGTCGTCGGCGTGGCAGCTCCCGCACACGGACACGTCCCCGGCCTTCCAGGCCGTCCGGTACGCGGTGATCTCCTCCCAGCGCTGGTCGGTGAACTTCCTTCCGCACCGCTTGCACACCGGCCGCTGCGCCTCCCGCTCAGCGGCCCGGCGCCGCTTCTCCTCCGCGTCGGCGCAGGCCTCCTGGTCGCGGTAGAGGGCGTGGCCGTCGGGGTTGTCGAGCGCGTCTGTCAGCGTCTGCTCTCCGGTCCGTCCCAGCCGCCGCCACACCGCCGCGCCAGCGCCGTGCTCCTGGAGTTGCTCCAGGGTGGTGACGACGACGGGGACCGCCTGGCGGTAGTCCCGCGCGGTGACCGCCTTCGGGTAGAGGGTGTCGTACCGGCGCGGCGCCCAGTAGCGGCGGCCGGCCTCCTCCAGCACGGCGACCGTGTTGTCGACCTTCGCCTCGGTGGTGTCGGCGAATACGAACGCGAGTGGCACCAGGCCCTCCCGGCCGGTCGGCGGGTAGACCCGGCGCCACAGCCGCTTCTCGTGGTCGACGTCCTCGATCGCGCCCGGCCGGGAACGGACCAGGTCCACGGTGAGCTTGGCCGCATCCTTCGGGAGCAGCCGGCCCCACTCCCAGTACCGGCGCAGCTTGGTCACCAGATCGTGCGCGTCCTCGGTGCGGCGGTCGATCTCCAGCAGCAGCACTGGCACCCCGGCCGCTGGTGCCCGCACCACCAGGTCCGCCCGCTGTACGTACCCGTTTCCGAGCCGGTGCGGAATCTCGGTGGCGAAGCCGAGCCGGTGGCCGATCCCGGCGCGGTGGAGTTCGGCGGCCGTCGAGGTGACCGCCGCGGCATGGTCGTCGTAGCCAGTGCCGAGCGGCTGGCCCGTGACCGGGTCGTACTTCTCTTCGCGCAGCGCCGAGACCCGTATGCCCTTCGGCTCCAGCAGCCGTTTCGCCTCGCCGTGTCCTCGCCGGGTCAGCACCCACACCTGCCGCTGATCCTCCTGCACCGACTCGATCCTCACCAGGTGGTGGTCCTCCAGGTCCAGGAGGGTGTCCCGCGTGAGCTTGTCGTGCCGGTTGTCCGGGCGGGTCAGCTTCCAGGACTGGTCGGGCGTAGCCCGCTGGAAGATCCCGAGTGCTTGCAGGAGCTCCCGGCGTCGAGGCCCGGTCGAAGTCCTCCGGTGCTTCGGGCGTCTTGCTACATCTACATGAGGGTTGTCGGACCTGCGATGTCCCCCTGTCCGCCGGGCCTGACCGGCGTCCTCGTGGGGCTCGTAGGCGCCGTCGGAGGCGAGCAGCAGCCGGCCCGGCCGGGCCGGGCCGCGAAGGTACTCGATGGCCGGGTGGCCCCAGAGGCGTTCGGTCTCCTCGTCGCTGCGTACTTCCCCGAGGCAGGCGGTGATCACGTTGCGGTCCCCGCCGTCGTACACCCGGCGGGCGTTGTGGTCCTCGGTCAGCAGACGCAGGTGTCCGTCCAGGAGGAGACAGGCGCGGGCGTCGCCGGACCAGGCGACCGAGAACAGGCCGCCGGGCACGTGGACGGCGACGACGGCCGCCGCGCAGGGCAGGTCGTGGCCGGCGGTGCGGGCGGGGTCGGCGGCGTAGTGGTCTTACTCGGCGCGCAGGCCGGCCTCCGCATCCGCTGCCCGGCGGCGGCGCGGGCCAGGCGGCGTGCGGCGGCACGGGTCCAGGACGGACGGCCGGGGTGTCGCCGACGCCGTCGGGCAGGACGTAGGCGCGGGTGCCGTCCGGTGCCGTGCACACGGCGGTCGCGTCACACTGGAAGGCCCGGTCACCAGACCGTTGTGCGGTGGCGTACGACGTCACGGCCAGGTCCTCGTCCGCCTCCTCGCGCGTGCGGCATGCCTACCAGAACACGGGCTCCGGCCGGAGCGCTTCGCGAGGGCGCGCCCGTGCCCGGACGGGGGAATCTCTCCCTTGCACGGTCAGGCGGGGGTCGGGAGCGGACCCTGTCCACGGCCGCTGGGAAGCGTCTGCGGCGGCAGTCGGTCCCACTCCCGGTGTCGATGTCCTCGAACACCTCACATCAGCACCGCACCGCGAGTGTCCCCTGGCCTCCCCCCTTGCGGCGGGTCTCGACCGCCTCCGCGATCCGCTCGAACGGCAGGGCCATGGTTCGCAGGGCGAGTCGTCCGTGGGTCAGATCGCCAAGCAGCCGATCGAAAACCTCGGCGGGGACATGGCGGCGGACCATGTTCATCGGCAGCAGGGCGATGTCCCGGGCCATCAGCGCGGGCAGGTCGACCCGCAGGGTGGTGCCGGCCACATAGCCGATCAGGACAGCTCGCCCTCCGGGCCGCATGGCCTGCAGGAAGTCCGGGACGGTGTTCCCGCCTACGGTGTCGAGCAGGATGTCTACCTCCCCTTTCCCCGCGGCCTCATCGGAGGTCGGGCGGACCAGCACCTCGTGCGCGGCGTCGGGTACAGCACCGACCGCGCCGTCGTCGCGGACCACCGCGACGACGTGGGCCCCGGCCCGCGCGGCCAGCTGCACACAGAACGAACGCCCGCGGTGCCGGGGGTGAACGGCAGTGCGGGCCGGTGCGCGAAGGTACCGGTCATGACGGTGAGGTCCAGGTGGGTGACGGCGGCGGCCTCGACTTCCACGGTCACCTCGCCACCCCCTGGCAGCCGGGGATCCGCGATCTCTTCCAGGCCGGGCGCGGTGTTCCAGGTGTGCAGACGAGCGGCAAGCATGGCGTACTCCGAGAGTCGGTTGCGTTCGGTCGGGTGAGGCCTCAGAAGAGCACCACGACGACACCAACGGCCAGTACCGCATCGGACCGAAAAAGCCCGCGCCTGCAAGCACCGGGCCAAGATCGAACCCTGCACGTCGCGCCTGTGGTGGTTCGGTGTGGAAGGCATCACGACATCACCCATTTGGGGGATAGGGATGCGGGGGTGCAGTGGCGGTAGTCCAAGGCGGGTGCTCGCCTGGGAGGGATGGCGGCCGACTTCCCCGGCTGCGCCGGGATTCTGTCCTGCGCTGCGTGTGGGCGATTCTCCCATTACTGCCGGTTCCGAGTCGGCCAGCGAAGTGTGCGCTCTATGGGGAAGTTGCCATGACCACAGCACTGCGTACGGTTCCCGACACTTTTCTGTCTCACACGGGCCACCCTGTCGATCCGTTCGACCCGGTGGCCAGCGGAGCGAACAGTGGGGAAATCGCGAACAAAACTGCCAAGGGGATAACTCTCTGGGTAGTGGGACTGGTCCCGGGCGCTGGAGGTCTGCTCGGTGCGATGATCGGCCCGATGCTGGACGCTTGGTGGCCTGACGGAAAAAACGACGCGTGGGAGGCCGTCAAGAAGGACGTGGAGGCGCTCGTGGACGAGAAAATCCAGGATCTGTACGCGGACCTGGTCGAGAACAAATTGGCAGGCATCAAGAGAGTGGCCAAACTGTACACCGATGCGGCCAAGCGGGCCACCACCAGCGAACTGAAGAAGGTGGCCCGCGAAGAGTGGCGCGGGGTACGCAGGGCAATCGAACAGGACATAACCGCGTTCATGAACCAGAAATACGCCTGGAAGGTACTTCCCTACTTCACGACGCTCGCGAACATCCACGCTCTACTGCTGCAGGAATTGATCCGGAATGAGAAAGATCTGGAGTGGTGGAAGGAGAAGAGCGATACTTACGACCCTGTTGACGACGCGAAGAAGAAACTCAAAGAACTGCTCGATCCGCCGTCGGAGTGGTCCAAGTCAGGTACTGGCGGAGGTACGTACACACGGCACGTGAAGGAGACGTACGAGCAGGGCATCGACAAGTGCGCCCAGAAGGGCACTCACAAAGGGTACGACTATCAGCGGTCCATGCTTCTCATGGCCGTCGACTACGCCCGCGACCTTTGGCCCATGCTGAAAGAACCCGGCAAGCAGTGGCCGGACAAGCTAGATTACGACCGGGAAGTATGGCTTGGCCCCATCGGGAAGACGGGTGGTTCCGGCTGGGACAACTGGCACAAAGAAAACTGCTACTACCCCAAGACTCAAGAAAAAAACGCATTCCTCAGCGCCATACGCCTTTGGCGATCCTATAAAGACGACGAGGACACGGACTACCTGTGCGCCTTCCAGCGATACAACGCCCGCGACGGCTGGGCGCCGCCAGAGGGGGCCACAGACGGAAATTACAAGGAATACGATTTCGGCAGCTGCTCGCCCGTCAAGATATGGATCGCGGGGAATACAGACGATTCCCTGGGGGCTCTGGGCCTCTGGTGGCCGAAAGACAAACGCATCTTCTATTGCATCAATCGCCATCACTCCGGCAATTGCAAAGTGCGCTACGGTAACTACCAGATGGAAAACTCATGGTGGGTGACCGACATACGGAATCTAAATCCGTACCTGGAAAAATGGAAAAATTCAGCGAGAGCGGTGATGGTCGGCTTCCGCAGGTGGGATCCTTGGCGCCCTGAAAAGCCCACACTCAAGTCCGCACACTTCTACCGGTTTACCGCGCCCGACACCAGCCGCGTACTGGGGCTAAAGCAGTACAGCATCAATCCGGACACCGCGGTGCAGGCCTCGGCGCCCGACGGGTCGGCCAGCCAGGAATGGCAATTGCAGGCAGCCCCAGAAGGCCTTTGGATCCTGGTCAACCGTTACAGCGGCCAGTATCTCGTCCGCCAGCACGGCCGATGCGTCCAGGACGAGTACCCCGCAACCGATCCCAGGCAGGCCCTGTGGCGGCTCGACGAACCCGATGCCCACACCTGGACACTCTGCTCGCCAGATGGCACCGAGGGCGTGGATGCCGCAGGCCATCTGCAGGCCGATGCTTCGACGTTCGCCCACTGGTTCGCCCTTCCAGTACTGGACACCGACGAACCACCCGTCCTGCAAGTCCAGGAGCTCAGCTGCGATTCCCGCAACAGCGTCCGCCTGACCTTGACCAACCCGTTCCCAGACACCACCGTCTGCGACTGGTCACTGTCCTTCCATGTTCCCGCTGACGCCGGGGTAGACCCCCGCCTGACCACGGAGGACGGAGCAAGGCTGCAGTCTGCGACGGCCGACGGCCGAGGGCTGCTGATCCGCCTCACGCCAGGCGGAACAGACCGCGAGTTGGCACACGGAGAAACCCGGACCTTCACCCTGAGCACGGCACCGCCCGAGGACATCACCCCCTCCGCCCTCATCCCTGCCGATCCGCGCCTCGAAGGCGACTACCGGCACGCGTAGTTCCCCCATACCCCAGCCGCCATGAACCGGGCGCGCCGCGCCTTACGTCTGATGGGGCGCCGGGGTCTGTCTGAGAAGCCCTGGTTCCGAGTGGTGTTCCTCCTCCGCGGCGTTGAGGTCGCCGAGGACGTGCTGCGCCGGGACGAGGTCGGCCGCCGGGTCCTGTGTCGGGCCCGGGCGCTCGTACAGCGCAGGGAGGTCGGGGTCGACGCCGTTGGTGATGGCCATCTCGGGGTAACTGCCCTTGAGCTCGACACCGTCGGGCAGCTCGGGCCGGGGCAGGGCGCCGGTGCGGATCATCTCCAGGACCTGGTCGTTGCCGTCGGCGTCGGCCAGCAGGGCGCTCGTACAGCAGCGGGCGGGACGTGCTGCTGGAGTGGCAGCCGAACCAGCCGGCCGGACCGCCGAGCCGGTTGCCGGGAGCGGAGTGCTCGAAGACCTGCGGCGGGAACTGCCCGGCGGGCGCGTCACGGCGCCAGGGGCAGGCCTTCTCGCCGCTGCACGGCCGCGGCTGTGCAGCCAGCTCCGGGTCGGCCAGGCTGGTGACCGCCGCAGCGTGGTCGTCGTAGCCGGTGCCGAGCAGTTTCCCGGTGACCGGGTCGTACTCCTGCTTGCGCAGCACCGAGACCCGTATGCCCTCCGGCTCCAGCAGCTTCTTCGCCTCGCTGTGTCCGCGCGTGGTCAGCACCCACACCTGCCGCTGGTCCTCCTGCACCGACTCGATCCTCACCAGGCGGTGGTCCTGAACATCCAGGAGGTTGTCCCGCGTGAGCATGTCGTGCCGGTTGTCCGGACGGGTCAGTTTCCACGACTGATCGGCAGTCGCCCTCTGGAAGATCCCCAACGCATGCAGGAGCTCCCGGCGTCGAGGCCCGGTCGAAGTCCTCCAGTGCTTCGGACGCCTTGCTACACCTAGATGAGGGTTGTCGGACCTCCGACCGCCCCCTGTCCGCCGGGCCTGAGCTGCGCAAACGCCCGGTCCTTGGCGACGGGGCACGGAGGGGGCGATGGAGGGGCCTCTCCGGTCCGGTCAAAGGGCTGCTCGGGCTCGTCTGCGGTGCTCGCCACAGGGTGCCCCTGGAGGTGGGGCGGGCCGATCCCGCCATTCACCTCGTACAGGTGTGGGATTCGATCTCCGTGTGACACCGGTCTTGGAGGATCCCTCCGTCGTGACCGCATCGTGATCAAACCGGGTGTCCTCTGACAGTGCTGCTGGATCATTTGCCATTCGAAGTTGGACCGCTGGTGTCTGGGATGCCCCTGATGCCGAGCGGTAAGGGGGCGGGAGCTATGCGCGGAGACCGGGGATGAAGCGGACGAAGCCGGCGATGCGCGGGCTGAACGTGAGCACACACTGCTCGCTGAGCGCCGACCGCACGCCCGCTGCCACATCGGCGTCCGGTTCACCGAACACCTCGAAGCGCTCCACCTGGCAGTGCTTCATCACCTCTTGGATGTACGGGTCCGCCAGCTTCCAGTGGGTGCGGACCGCATCGGAGTCCTGATAGAGCTGGAAGCTGTGGGCGAGCATCCGCTCCTCGTCCACGAAGGTCTCCACCATCAGCTGCGGCCCGTGCTGTTCTGCGAACGCCACGGCCCCGGCAATCGCGTCGCGGAAGCTCTCCAGGTGGCCGTCGGTGATACGCATGGTGTTCCGAAAGAGAAGAATCGTCGAGTCGTGAGTGGTCATGACTCGACCATCGCCCCTCAACCATGGTTGAGGTCAAGCGTGGACGGGTCCCAACGCCCTCCTCGGCTTCGCCGGGGTCGCTCTGGTCAGCAAAGGTGCCAACAGTGGCGCCGCGGCTGTCGTCTCTCAGCTCCCGGCCCAACAGCGTTGGCTGGACCGGGCGCTGGCCCGACTTCGGTGGCAGACGGCCCAGGTTCGCTGTCACCGGACACCGGGAGGGGGAGAGTCTCCCCTTTCAACGGCCGGACTCTGTCCACAGGGCAACGGTTCGAGCATCGGGTTCGAGGCCGCCGCGATCAGCGGGGCGGCCCGTAACGTTCAGGAGCCGACATGCCCGGCACCACGCCGCTCACCCCGATGGCCCCGCACGCGGCCATCAGCGCCTTCAACTACCTCCGCGCCATCCAGGCCGACGACGCGGACGCCGCCCGTGAATTCGCCGGCGCCGAACCGCGGATGCCCGAGCTGCTCGTTGACGTCGCGACGCGGATCGTCGTCCCGGTCACCGCGCTGCCCGGCCCGGACGCGGGCGAGCCGTGCGAGGACGCCTTCGTCCTGGAGGCCCTCGGGCGCGTCTTCGTGACCTCGCCGCGGATCTGGGCCCAGGCCGGGCCGGACACGGCGGAGGGCATCGCCCGCGCGGTCATCGACTTCGCCGCGCAGTTCCTCACCGAGGAGCATGAGGACGTCGCCGACATCCTGCGCCAGTTGAAGGCCGTCGGTGTGGGCCAGGTCCTCGGTGCCCGCTCCGCACCGGCCGGCGCGCCCCGGTGCGCCCGACCACCGCGTGGCGCACCGGGAAGGTGGTGGTGCGGTGCGGCACGCATCGGGCCCGCGCCACCGCCGCGCACCGCACCGCCGCCCATCGTGGTGCGCTCACCGGCATCGCCGCATCGCACCGGGCGCGCGCCGCGGCCGGGCGGGCTCCTCTATCACACACCCCCTTGACTACGATCTGATCGTCAGCCGAATCGGGTTGTGTCAAGACATCTCAGGGGGCTGAGAAGTCAACTGGTCCCTCGACAGTCGGCTTGTGTGCCATGGAGCTGGCGATCTTGCGCGGGTCACTTCCCCCAACGTCCAGTTCGTTCAAGCCGACCTGTTCACCTGGCAGCCTCCGCGCCGCTACGACACCGTGTTCCTCGCCTTCTGGCTCTTCCACATTCCGCCATCCCGCCTACCGGGCTTCTGGGACACCGTCGCCGGCGCGCTCGCCCCCGAACGGCAAAGCCATCTTCATCGACGATGGCCCCGCAGAGGCCGCCCGCGAGGAAGTCCTCACCCAGCAGCGCCGACTCGACGACGGTAGCCCGTACCGCGTCGTGAAGGTCTTCCACAACGCTGACGAGCTCACTGACAGGCTCGCAGCGCTGGGGTGGTCCGCCGATGTCCGGACCGTGGGCGGCAGCTTCATCGTCGCACCTCGCTGTCCCGGAACCGAGAGTTCGCACCTGCGGCCCTGCTGAGAGGAATTCTGACGAGAATTCACCGTGACAGGTACATGACGGATGTGGAGGGAAGGGCATACCATCGCAACACCCCGGAGGGGCGGCCGGCGTGCGTCCGGCCCTCACCGGACCACCCGTGCCACTCCTTCGCGCATCCCCCGGCCCCGCCGAGGCCGGATCCCCCCACACCCAGATGAAGGAGCAGCAAATGCCCCTCGGTATGTGGCTCAAGGCAGGCACTTCCGCTACAGCGCTCGTCCTCGCCATGGCGGGCGGCGCGACCGCCGCCACCGCTCCTGCGAGCCAATCATCCACCGCGCGGGCGGCAGCGGTGACCCTTCGCTACGACGACAGCCGCGCCGCAGGCTGGGAGGCCGCGATCGCGGCCGGAGTCGCCTCATGGAACGCGAGCGTGAGCAACGTCCGTCTGGTGGAAGCAGCACCCGGCACCGCGGCCGAGATCGTGATCGTCGCCACCACGGGCTGGCCGCAGGCCACGCTCGGCCCGGTCCGTCCGGGCCGTCAGGTCCGCGTCGAGCTCGGCAGCCAGGCCGTGAGCCAGGGCTACAACAAGACCCGGATCGCCGCTCACGAGCTGGGGCACAGCCTCGGCCTGCCGGACACCAAGCCCGGCCCCTGCTCACAGCTGATGTCGGGGTCGAGCGCCGGCACGGCCTGCACCAACGCCACGCCAAACACCACGGAGCGCTCCCGCGTACAGTCCGCCTACGCGAGCGGAATCGCCGCGCTCGCGCCCACCAACCGGACCCTCATCGACGCGCCCTGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP010849|29167:104722|35116_35482_-|WP_063856844.1|DBSCAN-SWA
MNKKMGIVWNLRLRMAEQGMFQTTELMPLLAERGIDLSREQVYRLVTHPPQRLSMDTLAALCDILGCTPNDLVEVRVTNTQVRKTAADGRGGRGGTGAGTPQHHPPGCTASTPTFAGTPTP
>NZ_CP010849|29167:104722|76312_77410_-|WP_044378004.1|DBSCAN-SWA
MTTTAPGNDIALALIAQDIMFLRRFAHNVTAAPDQAVIPIFCMHNYMCLIIHESHRALRHVDPDLADALAYDCAPAIERARHSVKLYDDKYKELDDVGADFRRIIEEHRQEFLDNTWLPLARPLEKDLVLWRFRGRLVSTSHTASFFLAFPPQAFKNQDELGPRLHAVAVEQGSYIAAAAEGLPWQGQTALDAVQKTDLTENEVRAEKHYRRSFDPALREETKASLTAMTCALNTVAVLLADDTNPSSATTLFKLRYITLHHVLSSLGKLDDQYGAELRPPDRALLKDILDAPMSNLILQAHRGFRNTLVHYRPTRDVRERLSLDAPLYGLLDAYFPADEARSLGDTLALHTAHVADRMSAWCDN
>NZ_CP010849|29167:104722|64259_65084_+|WP_044377982.1|transposase|DBSCAN-SWA
MQPRRRYPSDLSDARWELIRPTLQAWRDARAGIRRPTHSLRDLMDAILYVDRTGIPWRYLPHDFPPHQTVYGYFAKWEADGIFDQLTGLLRRLVREDEGRDARPSACLLDSQTVKTSANVHLADQGFDPAKRIAGRKRHVVTDTLGLLLAVLVTSAAVHDSTAGTHLLDHIATHHPRVSKALADSGYKNAVIEHAATRGIDLEVVHRTPGSHTFTVQPRRWVIERTLGWLMHHRRLARDYETHPHRSAAMIHIAAIDLMSRRLTHEATPNWRDT
>NZ_CP010849|29167:104722|87899_88265_-|WP_044378012.1|DBSCAN-SWA
MRRGTSEYEAAQEAMAEILLERARNGDWPIQYGQLSKLLEDEGHTVPAHSVEMDHLLADVSHQESPDREKAMLSAMVVLKEKGEPGAGFYRLAREEFGRKGDNVTIWGEEMKLLARDFRQS
>NZ_CP010849|29167:104722|44502_44898_+|WP_044377961.1|DBSCAN-SWA
MTMMRRLGVVAATAAFAGIAAISPASAYWEGISGTVYDDGWSHYSTKRCSTHEVGFAVTGYPDGDAMRHKPTSAQGGGGTVYSDVYFGGTTSSSDMGISSGRCFYWNARQYEGILETDWEDVWFGQINYRY
>NZ_CP010849|29167:104722|38788_39187_-|WP_044377957.1|DBSCAN-SWA
MTMMRRLGVVAATAAFAGIAAISPASASYEGISGTVYDDGWSHYSTKRCAQRTVSFLMDSYPDGDDMRHKPTSAQGGGTVYRDVYFDGHGAPEGMGIYPGDCFYWNSRQYEGTFETDWQDVWFGEIDYRGWS
>NZ_CP010849|29167:104722|68888_69545_+|WP_159392847.1|DBSCAN-SWA
MTDRPGSSTMTIALAAPGDGRAAVALGALAVSGHGAAPSALAQAIDTHGGQVPLPFGRGRCLIARIGGTVAGMVYTTPAIRWIQEHPPAQRAALVHSLVEIELLAVAESHRGQGIGTELLATAEETARSAGSHLALAKVRIGAFATMRWYRKRGYTIAAQAEPVIFRTRAGFESCDDGSDGYQLAVKTLQPGVVLRRRSERGSSMLVAEHVASNPGNR
>NZ_CP010849|29167:104722|93361_93694_-|WP_052808517.1|DBSCAN-SWA
MAQGWNTDSSPVLLTYEQVRAYELPSTEGKHGDPRWPAFARRHGFDPRHPVQWEVEALEPAELRRLVLAAVDSYVDRDVLARQIAREEEQRRALAAFLDGWDAAGGGTPS
>NZ_CP010849|29167:104722|89959_90955_+|WP_044378018.1|DBSCAN-SWA
MSHHSGPVVTTAQGAVRGRRQDEGTAAFLNIPYAAPPLGAGRFAPPQPHEPWDGVREATAPGPNAPQAERRLGSLDMVPYFGTGWSRGGDYLTVNVWAPAAAQGGLPVMVFVHGGGFVAGSARAALYDGSAFARDGVVLVTLSYRLSIAGFLDLPGAPANRATSAAEDVDDTAARSHPDPARLVETYRRTRPKASYGALRSAIMTDALFGADSRALATAHSSHTGSSTLAYEFAWRSHALDRELGAAHAVELPFVFDLTHLPQLLGPAALLGPDKPPADLAARMHETWIRFAATGDPGWDPYDTERRATMRIDAEWSQVDDPRGEERQVWS
>NZ_CP010849|29167:104722|104143_104722_+|WP_044378032.1|protease|DBSCAN-SWA
MPLGMWLKAGTSATALVLAMAGGATAATAPASQSSTARAAAVTLRYDDSRAAGWEAAIAAGVASWNASVSNVRLVEAAPGTAAEIVIVATTGWPQATLGPVRPGRQVRVELGSQAVSQGYNKTRIAAHELGHSLGLPDTKPGPCSQLMSGSSAGTACTNATPNTTERSRVQSAYASGIAALAPTNRTLIDAP
>NZ_CP010849|29167:104722|32067_32445_+|WP_044377952.1|DBSCAN-SWA
MTTYHLDLGDNQTEVLASVTKLTITHTELDIDAFLAADANAPVPLWGDVVLTRGNDRHPATTAWVEDVENTSTHQDVVLIAGDPADPKARRIRLTDAWASASYHLDEDDDPDAFAIAFTDITVEK
>NZ_CP010849|29167:104722|43414_43609_-|WP_159392840.1|DBSCAN-SWA
MHPEALRGWVKRAEVDEGTVPGTTSTDAARIAELEREVKELRRARAILKSALAFFAAELDRPLR
>NZ_CP010849|29167:104722|74195_75563_-|WP_159392849.1|DBSCAN-SWA
MSSQAERFFDDAVRTGRKNAVTMEMARRHCLNMTFTEFGGQGMAEAATGLPINTRQVSCLVAHGGASANLDWIVGEFYEQHCVGCSHRRPTGDVPNLATVMDERKEAAARAEEAERAETAKRHRAWEQRAEDRRGAQASSDPAMASALDDIGVLDQEPGTERDREVCDAALRRLTALAERAPETFSTPVIALALDLVTDVHVPELLTPLRHVARVRREHAANVLRAALATLRRSPVVEAGRCVADLLSLQDGGQVDEPVVRSLVYLAEPQSRRFGVYEGGTGDASALRVAAGAAPQAVARVLTSMLPAPRPSEPLVVPPGVRPAPQSGRELEMDRRAAATAVQALAFTHPDAAGALVPQMLLNLGVDGDHHNDPAPIATVQRSLATLLVLEVGDVPAQLEHTGRTAGDSVRERLFGVLEQAGRLIDPGYRFRTAGDPQLDASQQRRSLSICFPRV
>NZ_CP010849|29167:104722|45005_45479_+|WP_159392842.1|DBSCAN-SWA
MEMRGKWALAAAAAVLLVAGCGRDKDSEIPEGWNTKAEVQQQLAEERQKVSMPLGWRWQDKVEGADRDIYESGAAQAIVLDEATCAWSITWLKSAEKNDERGQKRAATELETLRELPAYQNNDSSYRDLVEDAQSKSELGDTSALRRYVDNNCETYK
>NZ_CP010849|29167:104722|46164_46842_+|WP_044377967.1|DBSCAN-SWA
MIAFEGVGKDVELHNGQRLTLLDRVDLAVGAGEFVAVVGRSGSGKSTMLNLIGLLDTPTRGRILLDGRDVSGCSDSELSRLRGQHLGFVFQQFNLLAKRTAIANTAAPLVFTTAYDAKERTRRAVEQLRRVGLEHRMDALPSTMSGGEQQRVAIARALVGKPRIVLADEPTGSLDESTGAQVMRLLIDEVRHADATLLLVTHDLDLAREADRVVRLEKGKVLEES
>NZ_CP010849|29167:104722|30638_30836_+|WP_044387170.1|DBSCAN-SWA
MNTNPLHGDPCPLCDRPLTLRTTVVVRSNVPYPTRTDSLPHCTVCANDLPNRQRWYDLMNDRYGL
>NZ_CP010849|29167:104722|98667_100797_+|WP_078968990.1|DBSCAN-SWA
MTTALRTVPDTFLSHTGHPVDPFDPVASGANSGEIANKTAKGITLWVVGLVPGAGGLLGAMIGPMLDAWWPDGKNDAWEAVKKDVEALVDEKIQDLYADLVENKLAGIKRVAKLYTDAAKRATTSELKKVAREEWRGVRRAIEQDITAFMNQKYAWKVLPYFTTLANIHALLLQELIRNEKDLEWWKEKSDTYDPVDDAKKKLKELLDPPSEWSKSGTGGGTYTRHVKETYEQGIDKCAQKGTHKGYDYQRSMLLMAVDYARDLWPMLKEPGKQWPDKLDYDREVWLGPIGKTGGSGWDNWHKENCYYPKTQEKNAFLSAIRLWRSYKDDEDTDYLCAFQRYNARDGWAPPEGATDGNYKEYDFGSCSPVKIWIAGNTDDSLGALGLWWPKDKRIFYCINRHHSGNCKVRYGNYQMENSWWVTDIRNLNPYLEKWKNSARAVMVGFRRWDPWRPEKPTLKSAHFYRFTAPDTSRVLGLKQYSINPDTAVQASAPDGSASQEWQLQAAPEGLWILVNRYSGQYLVRQHGRCVQDEYPATDPRQALWRLDEPDAHTWTLCSPDGTEGVDAAGHLQADASTFAHWFALPVLDTDEPPVLQVQELSCDSRNSVRLTLTNPFPDTTVCDWSLSFHVPADAGVDPRLTTEDGARLQSATADGRGLLIRLTPGGTDRELAHGETRTFTLSTAPPEDITPSALIPADPRLEGDYRHA
>NZ_CP010849|29167:104722|65300_66020_-|WP_044377984.1|DBSCAN-SWA
MTPGRRRHATSQRSLNEAARLADRLQAVGYTKRDIARIIDRDPSLVSQFYTKNKGAAFVTALREVLAAVETGGITDLTELAAIAARHTRRRTTASGTRARVRTKAVLITPTGTGTGRVGAQAIASGSTRLRPLIAEAARQGLRLAFTVRLAKTGYLHPAGSRTDSPGIRRDVIQRADHTEERSYGSAQTGGFDAADFARRVDAAGGDVTTAVHRWLVETGRIRPDAHILHLEVRTWRPR
>NZ_CP010849|29167:104722|93754_94231_+|WP_044378023.1|DBSCAN-SWA
MTGDWRMDRIGAALRGHNPTVLRRLESGFAVIGDVQFLPGYSVLLADEPDVQRLSDLPRAKRLSFLSDMDQLGEAVERACQRLDSDFRRVNLEILGNTDPFLHAHVWPRFEWEPAELVGKPVWLYPRDRWSDERFGLGPQHDVLRDAISSELDRLTLS
>NZ_CP010849|29167:104722|42926_43418_-|WP_078968985.1|transposase|DBSCAN-SWA
MKVAYIDQYKETFGVQPICDILAETDAPIAPSTYYAARTRPPSARSLRDEHLTKEICRIHKANYGLYGARKVHAALLCEGLEVARCTVERLMRAAGLRGVIRAKSPRTTRPAPETDRPADLVERQFTASAPNQLWVADITYIRTWLRSPLASSCTVGGEASRS
>NZ_CP010849|29167:104722|88596_89181_-|WP_159392852.1|DBSCAN-SWA
MTMSGGQTLDEPEGVLRVIARAAAVASARFDGDRFVLSVGVLEGAASVIGRLAAETEELADGEGETVRVLFLSGWELDYLWQVLAVFRRAQAGEPEAADLRELLHDLGYGLDRTVEQITEDLQRVAAMLMLDIPAVRTLAAAALHPLGLPSGHAGPPPDADAVREAVKCRCSATEEMSSLSQCRVSEIDPLTCG
>NZ_CP010849|29167:104722|100839_101097_-|WP_044378028.1|DBSCAN-SWA
MIRTGALPRPELPDGVELKGSYPEMAITNGVDPDLPALYERPGPTQDPAADLVPAQHVLGDLNAAEEEHHSEPGLLRQTPAPHQT
>NZ_CP010849|29167:104722|92760_93339_+|WP_044387189.1|DBSCAN-SWA
MPPSRWSRAAAEAMDTDAIQAAMPSPPISGGAAADRIADALGTPNVIGEKAAVTAFVVRRFVDRGLLADLSANPDGTLHHPDQVDQVCRRKDLADLVAADTPLGPEQAAARLRVRRADFDHMVRLGWVRSPQSIEVRFGTSRAGAVDVALYTTASVDAIPAAHPEVDWEQLRAVEKGRRSPLASLRPAPAPA
>NZ_CP010849|29167:104722|102085_102487_-|WP_044378030.1|DBSCAN-SWA
MTTHDSTILLFRNTMRITDGHLESFRDAIAGAVAFAEQHGPQLMVETFVDEERMLAHSFQLYQDSDAVRTHWKLADPYIQEVMKHCQVERFEVFGEPDADVAAGVRSALSEQCVLTFSPRIAGFVRFIPGLRA
>NZ_CP010849|29167:104722|59076_60144_+|WP_107070897.1|DBSCAN-SWA
MTSRRKLLTVSAATAAGAGGLTAVGVTSLPNGSSNRQKKAPAHLRGVVPLPYAQFISFDITGESERVDALRAAHQAIMAIDGGSVAAWLALGEGVFASSTNKPRHLKRMPSFAGDVLDPVRSHGDLILHITGSSARVVQQAVEQTLRALPQQQVRWRADGTRPENRIENGRGLSRNPFHFTEGHGNPGTAAEITERATVRDYQGEPSWAIGGSYEVIRIIRLATDFWGRDTIEEQERIIGRRKEGRWLDGTPSTERAIFAADPHGKTTPLDAHVRRAAPDRRNPPPTVRRSYNYHRGPDEQGLIFSCFQSDLKKGFEAVQRRLQGEALAKYTLTVGGGYFFVPPPGDAWLRATAD
>NZ_CP010849|29167:104722|91110_91965_+|WP_052808515.1|DBSCAN-SWA
MRSSLPSVRRLPRLLAAVALAGVTVVAATGGAPAHDRHGGRPIGGCAPDPALLFCEDFEELPRGAGTSLDWGVDTRNGALSVERERGRGHGGKRGADQVLRVRTEGNGYAFLEVDEFSAPDNSFFGRMRVKVDAFPTAPDWAHFTLVEAAGRGDGSVVRPIGGQYVPTVGDGVQLWGIGSDGGPTGDWTDWRESAPAEPGKWTCLEWEMDASDNRVAVWIDGEPQPDMTVTTTRHGGNPVDFVFPTFDTVRIGWQLYQGNPTPNSYDLRLDDLALSTERVGCGR
>NZ_CP010849|29167:104722|77901_81447_-|WP_052808514.1|DBSCAN-SWA
MELDDEGRYDGRLPACLTDAPTATTVPPPVETSPEVLPLAEVTWQNTERLFLRLAERSGTAEYAQQYGTPGQRQDGIDLYVRLAASDASSSSRRYLTLQSRRVKDLTPAKIRAAVDDFLAGTWAARSATFIYATTHSLKPTQLAEEILRQADRLDEASITFIPWGLESVSESLRDLPDIVEEFFGPSWATLFCRHPPTARQRISTPVPETSKATADWGAQLLGVHPAAPSPGQRLPAPGFVLPAYVPRPHDTEIRRRLERIADGSQFEFLVVRGSSCTGKTRTAYEAVRAVVPHWRLIHPKTAEAVVALVDAQTVSSQTVLWLDDAHHLFNEPAGESAAAALRHLLERPGPGLLIATMWPQHYDALVTPDPSGNDLHPQTRELLRPFSAIDVPNRFHGRPLEELNDLAQHDSALRAALETVSEPGAVAQTLAAGPDLLDRWEHARCPYGRAVLTAAIDARRLGVRTPLTKAFLHDAAPGYLTDHQRAAAPADWFERATQYCEQPIKGVASALQPVALPTGMGATPGVYALADYLEQHAGEKQADQPLPTTFWEAAEHHVTDGAGLTWLARHAWSRGLRKRAVLTCHKALILQAPFAAGWLVTFIRQLEAEAHAYSWIARRAPLTDPYAVSFLLDELKEAGRSDTIDIVLRREPELHAAADNPYYVALLVNSLKALDRPQAVSELAERAARSVPFEHVGAVAYLLETLLEADAHQAVQTLLRRDPASRVRLKEPYDIYGAPYDDTYDAIILLELFGEAGAHQAADALAGRIAKLAPANDPWDFGRLLTALDQVKASRHIDTVINRAVREVPVTDGGAVANFLTAMLNEGTMAGVDAFHALLEQGPVHHVRLDDARTAARLINTISVAEWHEEALEALLGRDPASSVELTDPMGVAMLLESLHAVGDRESASRLISRSPAAHVELTDADAAGVARLYRVFLALDAVDETETLLTRAPVDTVCADSLRKTVDLINLYDSLGRNEEASRLVQRVGSRMTDWEPLLDVSLEDLARDQLRKKFLRTLAAHVRLQSPQTVTGLLRLMHKQDATGALTLLLARKPSECVTVHQASDAEELIDALVEAAGPAEAARLAATGLADKVFFYGHHDVSGLSRALLRLGAAEENARLARRALHAGSFNTYVQCMDRNASDYRYGIEAEDQPSPQWSLQRSLWEELVPQDAEQAG
>NZ_CP010849|29167:104722|58350_58785_+|WP_159392845.1|DBSCAN-SWA
MSLPDGWEWLDETPSEWSPPSELRTPTGLLRVDLPIKMLSSNTLGNDLIELVGRLLSESARFNIWFGSEAKGKANSPKQLAVLSQTMNKQLHHIYEAWKPFIGAYKASGGRVGTFKSEENALRQALTDAINILSATRKSFRGGD
>NZ_CP010849|29167:104722|49457_49877_-|WP_159392843.1|DBSCAN-SWA
MFEDGVSNAEIARAVGVCAESVRRWRRVWEQGGASALRRRAATGRPPKLDDTQVGMVRAALEQGAQAHGFEADLWTLERVGAVVTRTAGVVLSRASVWRLLTGRLGWSLQRPERRAVERDESEIARWIAHEWPRIKKGP
>NZ_CP010849|29167:104722|94306_94492_+|WP_078969453.1|DBSCAN-SWA
MSTPPDGLPIYRVLTGPDDVAFCHRVSEAIALGYELHEGPAVTFNGERVIVAQAVVWPAQP
>NZ_CP010849|29167:104722|97631_98384_-|WP_078968989.1|DBSCAN-SWA
MRYWPLVSSWCSSEASPDRTQPTLGVRHACRSSAHLEHRARPGRDRGSPAARGWRGDRGSRGRRRHPPGPHRHDRYLRAPARTAVHPRHRGRSFCVQLAARAGAHVVAVVRDDGAVGAVPDAAHEVLVRPTSDEAAGKGEVDILLDTVGGNTVPDFLQAMRPGGRAVLIGYVAGTTLRVDLPALMARDIALLPMNMVRRHVPAEVFDRLLGDLTHGRLALRTMALPFERIAEAVETRRKGGGQGTLAVRC
>NZ_CP010849|29167:104722|71319_74145_-|WP_044377997.1|DBSCAN-SWA
MIKQLAQTHPAWTQPQLAALLGAALTAIDTLESANTTPTPLLAAPEPAPPELQFLERMAYRQSLASSIGRLLDALEHIATIEATAVCGAVIDTITDERDSQRKHVIVPRLLPLLGTIGRRHGDHPGLLRMIIPLLHTYIVDSDVASRSAALTAWADIGRAHQLPSSISDLLPALLTDPYLGVIDGVLDTALRLDWSTEDSASLLAYALSVCEHVDIARFPDTVKKAMAAASKHSRGNEALRIHTEQEILRRAADLDGYDLRDALNRDWLPQTATTPAMAQLRLRQVRDPRVNDRLNAHDNLELCALLNCGSGLASLTVEDLQAAALELGPHQVVGAAEYAEVAWRAARPGDAATILNSVLKTTPDEPAFTLHRALLTLIAAAATFDAAAVAGEDMRATALALTHAAQAIGADNDASALADQARTRVTVRSLLTGHELVPAAGAGQGHSDSDPAVALRGRAAHLQSTAATLREQCQQATATAAYGRCFAALCEVAAFLIRLDAAELDADTIEMNALVTAARRRAAVTATELEKRFHGTDPLAGPLIAALRQVQAVADASGVADLLAEWAALPLPLVIARGPRRTPLTSHTVFGNEADTRLVEDQPTVAVVLASVDGRLVTGPQVLRHSTVYELRLDVRTGSWPEWAETLEAELLSHFTPNEAETPTYLWTRPPSADGPDTLSATGTLILRFALPAGSPAPPFSVKLRWRGTRDGKPVTESLDTAGHREIRFRPFDASRDFLTNFPVFDERLLALYENLHRAGYDEDQLQAFCRLFTAICRTGLTMTWNKHYKRGSHVTERKFHDDLYKELQAEPELGGRLQRGTPLALGYLDVRHDGITAELKVERNTPVTRDRARKYMGQPTQYAAADGARLSILCILDMSRKASPVGVPENYLFTLQPALHGLTNPEAPSLVAVIVVNGNLPSPSSWSRRKTPTLPPSAP
>NZ_CP010849|29167:104722|60272_63038_-|WP_159392846.1|DBSCAN-SWA
MVCQGRSCLTAPPTSVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLDDIRVEHGITHLKNWRVITSYRIHYTKLYEAAQGTFVTTHPRRARHRSPEELASSDPPPRPPRAHERHCPGRRRPAVPPADCGPDVGAADVNTEPRRHPRRLTAYRARAR
>NZ_CP010849|29167:104722|83992_87637_-|WP_044378010.1|DBSCAN-SWA
MSQTALDGTPWSAVDGPSLARAAAALQLIPQNVPRLVRLQRLAGVAACLPHRPEAPRLSPSRLRTLLKNPVIAGLDVRAQEDPYDDLYTAEIAFHGGPYLVAQGLTSRSAFTLNLLLRSIFGPNGTTLPGAFRQEAHALTDAVLRLSHTVLIRAGLGRGIVVPTARNTEVFVPGAGELSRLCEAVIFDKPTWQQLVPGPVAELLAPLTVRPGQHTFPPGPGPDETLVLTPVLAANDSMIVANPGELAAALRHRLFVLAGAYNCRPQFAELLRREVLQTTTRTLTQCGARPAGPESHISDVPLSRRLFTVADDTFLDLLVITDDLSDYDDEDPYGQWNAQTHSQRVQDLLDPPGTPTEHDARTLRMVINQSFGRTMFLGIGSLRRPGPFLMLTADDLQVMADLDGGDPLFLWRFAQAETALRNDVQVISFGTLDTYGLYREHAHSFYLTDERRPTLVTVDSDFSTHLRTEAHRRFDRHEVSHPDRDTLVAVSAVYGTDTAPVYRTEAPTGGQDLLVELAGLQVWVTAPGVSTSAPAALHDCFLEAAAYWIWQLAGAAPGLLPAAAGDQDSLTVEMSYDPRAWAAALAGKEATDGTDPWIRADTSAPGQLRLELSAAGWPLLQQETNDAERILIHALATAAAVAADTTTDLDDLIDRIAPLGPKKMLHVVSGQELLLRSDSLPAPRLVQPAVSAVVLDELGQWLTREGTPPGAIAPDQRLRVLNQVVAYYFHLLQSAFAELSPDGLLRQLLQRHEALLNADAVSHQGMPARIACFGPTSQTAQELARISRRRVEAAQASRFLIEYAAAVPPSGQQQLTLDRYDRLMALAADLISRAMLSDAIRHEFSDVSLSLLDSGRLGVSRADRFETGTNTLALARAEAALQGAAARTITPAGSQAKPPSSAVEEAMRAEFGFTLTELADGIGTLIALGEEHSPSESVLLPAADVTQHLNVALGWPEGKTTAFLHRLSLQPRADFLSVKADAWPWRFNREWSYARRPLIQVQQDNTACLAWAPRHLWSTGGYWSNLVYSGRLRATSPAMKTLLGSIRQDNNKDFERQVETALEQAGCQITACGVAKIQGRRLTADGHDLGDIDALGISLTHKKIFVAEAKDFEMARNPAELANEADHLIRGDKSARYKISRRAQWIQSHLAATLHHYTRSSDTRGWSVIPVIVTSRDLMASRVLQSDVPVVPIAQAAEWVRAASRRAPRRRGSR
>NZ_CP010849|29167:104722|40208_41918_+|WP_159392838.1|transposase|DBSCAN-SWA
MLVMLRMSKVELYAAIRRDHRGGMSMRELERKHGVTWRTVRKALDSSWPEPRKKLPPRATGLDRYKPVIDEILRADLDAPRKQRHTVTRLFHRLVKEHGADVSYGMVRYYVAARKPEILVESGKAPLEAFVPQTHQPGHEAEVDFGDVTIRLAGELVTCYLSSFRLSYSGKAVHRVFASCGQEVFFEGHVHALRTLGGVPRTKVRYDNLKAAVARVLGLSRARVEADRWIAFESHYDIESFYCRPGIKAPTRRAASRARTATSGATTSSRFRGVLARRAERDGRAVGPAGRRPQDRLRSRTIAEEFALERPLLMPLPQEPFETGQLFTPRVDRYGQIPVRTNRYSVPIRLIGKRMRVILHASHLGVYDQNVEVARHERLIAKGAVRLDLDHYLEVLVRKPGAFPGSTALEQARSADKFTPVHDAWWTQAMKIHGERDGTRALIEVLLLGRHMTHEHVVAGLAAALRAGAMTADAVALEARKAAQAETEPAPDARTLGQPPATVTSLHEWRLAHLPPDTRPLPSVSHYDQLLRRRRTSGSGHRVLAAAEVAGQSSPVLQVSDAVLDADAS
>NZ_CP010849|29167:104722|45475_46168_+|WP_044377966.1|DBSCAN-SWA
MTGRSHRFPRIAGAGLLLLVGSFAGGWVGQQASADGDADLRTQQPLSVPTARHVTAERGSVQAVVVLDATVVAADSGASQSLKQSSLVEAQIRPEQLARFSSLPSTGKAKVDGGPATTDCRLSALITGEGSDILPRIRCTLPQPVAYPGVRAHLALSAGQVHNVVVLPLSAVDGSSKRGMVHLVQGGTSRPQTVELGLRDGVNVEISSGLEAGDTVLDPPPSLFASDDQK
>NZ_CP010849|29167:104722|66019_68101_-|WP_044377986.1|DBSCAN-SWA
MDAQSYNAGLAELRTVRDQVKKVRAELARLEANRDKRIAHLATYAKAKAERIAPAAGLSVADVVAVAPTLAPDHLAQDDEPAAQPEAQAPALGATEPRPTGQPGATAPVILPAHPHPEPSAPPAAAPATPAGPRTLPGIPEGEAGDAWFTHTAGLASTRPNFTQQARSTVFLDATTGVLVHRNQTHHLDLADRSAAAILTAVFHTIPDGVERIYITAGDPWHRDADRYPYLRDAVAAWLSAPIPGWRTDTGRGRDRMAGHFVHARNPVGRYQRENSDQHVEIRSVGEWFDTDGDDPATIRDAFVLLWQALRRHWNDAVIMGSPSQTGRDLWTRTIPTRGQHADGFPVLSEELRGLLHATAGQGRNELITPPRVPEQLPRLVEYDRTFAYAKHTWKSPVGTPRRITATTFASWSEKEQIRALYGCGHWHVRVTVPDTWNHVGLLPAPAPGDRAWHYPAAPGTTFTTWAGGPEVHTALTNPIQPWKIEILDGILWEDGKPLEDWAKKLKETWTNLSAQAQYHGDPQQARAAHLASRAVRSILLYGIGAFAQRPRMVTGTTPRNMERDVPPDAEIIAFDDKHITWQKPTGFARDPNAHPEWAATIWSGARAALLTQRHRDDNTYAGALHTSPGSVVAFRTDALYLTERQNWPYHHQPGDYLLRGHLTGPLPAPTGEEELLTLRDAGRTALTTSQEP
>NZ_CP010849|29167:104722|35478_36600_-|WP_044387174.1|integrase|DBSCAN-SWA
MEGRVDLPGASHLVLVKHVVPLDPEPTVFEAILEGWARQQRVRFLKDDTINRRLALVQRLARFSGQYPWQWNAAEIEAFIDHLRSTSRSFAVSTARGHLGNLRMFLEFVTDPRYGWTAVCRERFGEVPQQVLGEWNTIAHTDDYEGRPGRRPFTYDEVQVLFDAADGLAEEIRARRRKGALAAQRDAALLKTFYAFGLRRREAWGMDRVDWRRNPQMPALGRFGVAQVRWGKSSRGGPPKRRTVLLVPEMDWAVPVLDHWECELRPRFSPGEHPAWWVTERRGRMSCRRMDEVFAHVRAVAGLDEELDLHCLRHSYITHLIEFGYPERFVQDQVGHRYGSTTAVYTGVSLEYRNRLLNRSLQARHTELWEPTS
>NZ_CP010849|29167:104722|69863_71072_-|WP_159392848.1|DBSCAN-SWA
MKPDNRIPKPRSSAPQRSSTSQDLISQNVTAALAAHDGDPHKATAALTARAIPDAMALLNACRVGGRYDIVHHPALPGMLRKPGPREPDLIWEARLNWQRPEAPEHTSPVAALDINGAFLSALKTHLPLGRLEPSNPEHHDRRRAGIHLITPPPWEHDAYLPNPMGPRQEPGPVWVTEPTLRLLLRLSGPGHALCDPPVIHESYTSGATENLLEKFRTTLRDARARALDENDKVTLEYVKAMYAKFVSTLGESTQNRELRRPDWMHVIRSQAFANLWSKAYKAHAEGLTLVRVCGTDELHLQGDWLRTFPEGRNLNQMKLKETYPISMIYPEVKQITQTSCNSPDFEKRRYEYAGGRYVGCRTCGGDLCTSCRNAHLRPSETPYEYNDDNVCNACQQNESRD
>NZ_CP010849|29167:104722|44296_44479_+|WP_159392841.1|DBSCAN-SWA
MTMMRRLGVVAATAAFAGIRITSYNVCYTKLLRIRGVTLGAAVTLTVATGGSQVFPLRHA
>NZ_CP010849|29167:104722|81954_83577_+|WP_159392851.1|DBSCAN-SWA
MASMLVNPFRTRLAPTPPGDGESEGEGPPQAGDFTHRAAVLVRVPAGAEEATAREQWARCGLLFSPLEAAGDDATAVYWVEVRLQGSRWGALTEAERRVTAALAGRVSAHIADATLLEPEVTPTVVSTWHMHRKTDWGPGWWRSRAAQLWVQVGAADVHRRVRLDGPGTREEALAALQRGPDVGGVHFDENLHDVRPGIASAHAVRPQDPAPWQTRALGLPGMAVGAVAMLFGWMLAGLGLGWQMALAPLLVVGAWWVGPWLADRERHSGVVVWLCGLAVVGGTGLCGFMIRVVSAALGGVDVRAVVVMLCGLPVLRGCLYALRQSWFSRNAATVLSLAVLPLAWVLPWMGRLVQGIYLTVCLGIPLSAVNVDALWTYLAGVKPTALCIAALLCGLAALGWCRHFYWITGSRTYYLAVFGTFTVVMMVVAVLVGLSSATNGADRTVAQAVAGQDPSPFFGISARRVCVRPLDAANTAVQPGPLPTGYPVVAFDVTGDETWLWDYRRATASADLAKGALRVRTDQVVTQPAARGARTCPPL
>NZ_CP010849|29167:104722|46838_48002_+|WP_044377969.1|DBSCAN-SWA
MRFRSLLMAVRDELAANPTRSSLAAASVVVGITCLVVVVALTGLGEQAIRSEIERTAGRAATYQIDGLKSDDPKLVRTLTDAMDQRLDQLGISAHSRYDGYSATAPGETNAELFAIDRSYSRIRTTDVLQGRWLNSDDDHRYPISVAANGAAWDALPNSRPGAVTVLHVGGSRITARLVAHIDDGRSEATLYVSSTALHAAQVDLPTPQPGYLYAVTPSDATQLAQDIARIPQNLGAEGVSLHRVDDSDAFQRVFRIVQGFGVGAAALALAAGSLGFLNLGLASVQQRVRDFGVLRSFGATRRAIFVTVLLESVAITFAAGIAAVALSWIAMQAVPTVGGISFAHADLSVSAIITGLIVSVALGIAVGLIPARRATRVNVIEAIRTA
>NZ_CP010849|29167:104722|41878_42031_-|WP_159392839.1|DBSCAN-SWA
MIAERVAELGPLWHERHVITSYSIHYTKLYDGSARHIRHDASASSTASLT
>NZ_CP010849|29167:104722|50486_58316_+|WP_159392844.1|DBSCAN-SWA
MTVGTLVLALAAGAVSAEALPTEPKPSKSSAPTASADAPSFSSKAKPAPQKTDTVDTAEPTTGNAVYAYDAANRLVGVTDPDGETARYRYDAAGNRLGIDRFTSSTLSVLSVVPVRAPVGAKLTLSGTGFSSRAEGNTVTIGGKKVVVASASATRLVVTVPADATSGRVTVSTGGSTAEGLEPFTLASAPAVSKVEPASGPPGTEVTITGAHFAKAASDNVVRFNGGTLAETIQATDGTLTVKVPAAATSGRITVQTQDGKATSASDFLIPLSEDEETFETTIRTAINDAPSSVAVTQAGKRARLFFDADQGQDLSVGFTQATFTPSGTAELIDPRGDVVGTSSNILPGSDDWEVRDLPVSGTYTLVVNPSSTTTGSVTVTLSEPVGGELSFAGNPAATVMSRAGQDGLWTFTASVGESFSLGIDTASMTDSLTARLYAPGGEQVDSLSVSKAFDGSLDLDKLPASGIYTLYLDPANGATGTATVTISHFASAASLDPQADPKQLAISRPGQDGTAVFTGTAGQKVSLGITSAGFTTFVTYYVYAPDGSKVDSFTVSAAGTTDWDSAALPQSGTYQLRMSPARLGTGALTTTLSTLVDAGRLSSTGSSEFVDISRLGQNAEATFNASSGDDLSLAVTENTFTTVASLTVTAPSGAKVAPSVSVTSGKAHTQGLSDLPEAGTYTVTVDPFSGAQGSMKLTLSTDITVNAAVDGTSVSATAARPGQRIRARFSAGSDLVSVGLTSNTINQSTDLTLIGPAGGNGDAVGAVGKSTTQAAHLGPLYAGSAYTLLLEPQLAGTGSVTLWLSAPAKAGALSATGRTGTINRPGQQLEYTLAAQAGDGTSALFTGTTLTGTTAVKILSPASAVPNSLGNLTTSPTDVDVRAPLAAGTHRILVQPSKPVTGSTTATAVADVDGGVLTVDGSSRSASIGTAGQNARFTFTGTTGQKLTLNLGTAPPSAWYLSIYGPNDKWLVNERPMTTATLAYALAALPTSGTYTLTVAPATMKTGTYSLGLSTTAAASTADSGRKKETKSSAKKASDHAGVDREASAGGTVPTGADAWQPDKHNLKGLDWLTRRGATPKTPVRLRAPPGKTAVSGHVLRLDGKPLAGVSVRVGTKRTLTDAKGRFLLVGISPQATTLIIDGSTANTKKRAYGRFEIRIHPKAGMSVDLGFPVWMAPLDTKHTVTFEATAKKDVVLTTPSIPGLEVRIPAGSVVRDEDGKPVTELGITAIPIDRPPFPLPEDGIVPVYFTVQPGGTYVFPKGAQIIYPNYTREPPGTRVDFMDYDPDGKGWYVYGHGEVSADGTQVIPDAKTRVWAFHGAMFNVPSLPNWLTGWMDDTLSWLSGDPVELSTGLLTDTHTDLAINDSLTPIEISRTYWQGDTSKRAFGIGRDLIYNAFLHSEEQYKEVDLYLPGGRKVHYVRTSSGTSFRDAVFQPTSASGSFRSTMIKWNAGWELSFPDGTVWEFPQYSPLNEIRDRYGNTLTLTRANRIRGPITRLVTSNGRWINLTYDAQNRVTQARDNTGRTTAYTYDSVGRLETVTDPAGKVSSFTYDGTSNRIATAKDARGIVYMTNTYDTVGRVKKQTLTEGQEYTFAYTQTGTGQITATEVTQPGGSVRKVEFDTSGFGISDTQAYGTALARTTVYERGTKHRINAVIDPYGRRTELSYDNANHITGATELAGTAQARSASTVVFDGPYDQPSSITDPLGHTTQLTYEPNGDLTKVTDPEGRKTTFTYTSTGQVKTVTDNANATTTYTYDNGDLTQVKDAEGRVTQQFTDAAGRVSAVTDEAGSLSAITYDKLNQSREIADPLGHTTALGYDANGNLTTLTDARGNTTTWAYDNADRPKTATDPLGAQASFEYDTAGLLKTATSLSGKAATAEYDLLGRPKTTKYGVNPLGQAESTVTYGYDAKDLLKQITDSQNGTQSFTYDAYDRPATSTGPTGTVSYDYDNADRRTLMTASGTSTTYGYDKSSILTSVKTGTQEVTLGLDAAGREKSAALPGGITRTTGYDTTGVIESLTYAQGTKAIGDLTYTRDVRALQTGLTGSLAKIALPAAESGTEFGKDNRITTYAGRTFTYDTDGQLKNDGIRTYTWNARGELTNLIKAGTASSFAYDPLGGRMSKTTGGTTNRYLTDGNNPLVEQDSAGATKATVATSGLDEFLTRTEAGKTQIYLTDALGTVVGLANTDGTIATSYAYDPNGTPTASGATSSNPYTFTGREDDGTGLLYYRNRYYDPQTGRFISQDPIGHAGGTNLYQYALSSPTTYTDPTGNNPMIAGCVIGGLFDGGMDWLAQRLSGRKVNWGQVGQSAVIGCLSGTLGAGIGAKIGSRVNCTSPNSFTGDTPALMADGTHKPIKDIKIGDIVLATDPETGETGPRKVTTLINGEGYKQLVDITLKTDESKDSSTEKITATNGHPFWVPTLHRWIEADDLKAGQWLQTSAGTWVQITSVRHRTQSGSVYNLTVDDLHTYHAVAGATPVLVHNCGSKAGEAIVHLDRTAGHASITVRHGDDILHTEQAGVPGTRAVPQNFVGELSDFRVDVRIPLPNASRARSYQDVTLGRDLGAYDEATRSCITYCAEVLRAGGVQGIPIEEGSLAITRWLIKMHG
>NZ_CP010849|29167:104722|68129_68726_-|WP_044387179.1|DBSCAN-SWA
MLLTTGQVAEELGCAVTTFRRLVQAGLLPGLSRRGVRVMTPLSVVQALSARPSAALQQLDVKEVPVLRVDVAKPVDDPEREWIGFTASLGPEDLLKALRGWWRCDPASVAAAGVLPVTLSGYVVAVLTGLERWERNAEGRYAFPDARLAGYVTDLATPRLTITARTNRDRKLAELLLGTRLASHSGGAIAYVPTTSTD
>NZ_CP010849|29167:104722|75700_76273_+|WP_162487300.1|DBSCAN-SWA
MRPAWRRDSWLAREQKDDEAHVQRSTRYFDEFRARQKKTIALFPSNGVSLKAAEQLLHLPDSVVEGPQAIAKGRKPLPPIDELLLAMGEPFPQPGWLPAAFSLLSQVTHSTPTGRAHMARYVDGTLRAHDISPEMLALALDVACLGSARLIGLSYLLLTRGDDTAKQYALGLEERALAVHNTARLVHWLD
>NZ_CP010849|29167:104722|32645_33590_-|WP_159392837.1|DBSCAN-SWA
MYAIRSYARITSYNVCYTKLLRALQPWLERTLATLPPQHRNLLRTYAQWSVLRQARRRAARRRFTSASATRARNTIRCAGAFLLWLDEHHTALADLTQHQVDLWLTGPLERRHVRPFLRWAHQRRLTGLHDVRPRPRGEAPTWFSDTEHWAHLQRCLHDDTLPLDVRAAKALMLLYGMPVSKITELTSDRLHDGDQPVLILGDHPTDLPPAVHRLLRRQADHAHQESAIGRTTPPATWIVPGYAPGTHRSPAALAAKLRRHQMPAHPSRNTALLTLATDLPAPVLSDLLGISITSALHWTRRAARDWNAYLTSR
>NZ_CP010849|29167:104722|29167_30415_+|WP_044377947.1|transposase|DBSCAN-SWA
MIDEHADAGWERELDDLFLCIGHRFGRADLRRRMRDYVRGLLAPVGRKNGWQLAEFAGHRTPDGLQRLLNGATWDADDVRDDLQSYVAKHLGDDNGVLVIDDTGFLKKGTTSAGVQRQYSGTAGRTENCQIGVFAAYTSAAGRALVDRELYLPKSWTDDRERCRAAKVPDERGFATKGELAKRLVLRALASGLPLAWVAADAAYGQEGRFRRMLEQSGLGYVLAVPKSQQVFGPRIDHLFAQAPVEAWEPISCGNGAKGPRLYHWAALELPTVAEFDYQGDVPVRRRWALARRSLSRPEEIAYFLAYAPPESAVADLVRVAGMRWQIEECFQAAKNECGLDQYEVRRYVGWYRHITLAMLAHAYLAVMAADAAAKGDAETLLAPWLRSPWQKSGGCWRLASPGTAEVAGRFARTC

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
29012:29071	attL	NA	NA	NA	NA
WP_044377947.1|29167_30415_+|transposase	IS701 family transposase	NA	NA	NA	NA
WP_044387170.1|30638_30836_+	hypothetical protein	NA	NA	NA	NA
WP_044377952.1|32067_32445_+	hypothetical protein	NA	NA	NA	NA
WP_159392837.1|32645_33590_-	hypothetical protein	NA	NA	NA	NA
WP_063856844.1|35116_35482_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_044387174.1|35478_36600_-|integrase	site-specific integrase	NA	NA	NA	NA
WP_044377957.1|38788_39187_-	hypothetical protein	NA	NA	NA	NA
WP_159392838.1|40208_41918_+|transposase	IS21 family transposase	NA	NA	NA	NA
WP_159392839.1|41878_42031_-	hypothetical protein	NA	NA	NA	NA
WP_078968985.1|42926_43418_-|transposase	IS3 family transposase	A0A1B3AZE5	Gordonia_phage	5.7e-31	51.7
WP_159392840.1|43414_43609_-	hypothetical protein	A0A1B3AZF8	Gordonia_phage	9.1e-17	70.3
WP_159392841.1|44296_44479_+	hypothetical protein	NA	NA	NA	NA
WP_044377961.1|44502_44898_+	hypothetical protein	NA	NA	NA	NA
WP_159392842.1|45005_45479_+	hypothetical protein	NA	NA	NA	NA
WP_044377966.1|45475_46168_+	hypothetical protein	NA	NA	NA	NA
WP_044377967.1|46164_46842_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-32	38.8
WP_044377969.1|46838_48002_+	ABC transporter permease	NA	NA	NA	NA
WP_159392843.1|49457_49877_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159392844.1|50486_58316_+	hypothetical protein	NA	NA	NA	NA
WP_159392845.1|58350_58785_+	hypothetical protein	NA	NA	NA	NA
WP_107070897.1|59076_60144_+	Dyp-type peroxidase	NA	NA	NA	NA
WP_159392846.1|60272_63038_-	hypothetical protein	NA	NA	NA	NA
WP_044377982.1|64259_65084_+|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	3.2e-10	39.1
63046:63156	attR	NA	NA	NA	NA
WP_044377984.1|65300_66020_-	hypothetical protein	NA	NA	NA	NA
WP_044377986.1|66019_68101_-	hypothetical protein	NA	NA	NA	NA
WP_044387179.1|68129_68726_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159392847.1|68888_69545_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_159392848.1|69863_71072_-	hypothetical protein	NA	NA	NA	NA
WP_044377997.1|71319_74145_-	hypothetical protein	NA	NA	NA	NA
WP_159392849.1|74195_75563_-	hypothetical protein	NA	NA	NA	NA
WP_162487300.1|75700_76273_+	hypothetical protein	NA	NA	NA	NA
WP_044378004.1|76312_77410_-	hypothetical protein	NA	NA	NA	NA
WP_052808514.1|77901_81447_-	hypothetical protein	NA	NA	NA	NA
WP_159392851.1|81954_83577_+	hypothetical protein	NA	NA	NA	NA
WP_044378010.1|83992_87637_-	hypothetical protein	NA	NA	NA	NA
WP_044378012.1|87899_88265_-	hypothetical protein	NA	NA	NA	NA
WP_159392852.1|88596_89181_-	hypothetical protein	NA	NA	NA	NA
WP_044378018.1|89959_90955_+	carboxylesterase/lipase family protein	A0A0M4JT58	Mollivirus	7.0e-12	36.3
WP_052808515.1|91110_91965_+	hypothetical protein	NA	NA	NA	NA
WP_044387189.1|92760_93339_+	hypothetical protein	NA	NA	NA	NA
WP_052808517.1|93361_93694_-	hypothetical protein	NA	NA	NA	NA
WP_044378023.1|93754_94231_+	diadenosine tetraphosphate hydrolase	NA	NA	NA	NA
WP_078969453.1|94306_94492_+	DUF1737 domain-containing protein	NA	NA	NA	NA
WP_078968989.1|97631_98384_-	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_078968990.1|98667_100797_+	hypothetical protein	NA	NA	NA	NA
WP_044378028.1|100839_101097_-	hypothetical protein	NA	NA	NA	NA
WP_044378030.1|102085_102487_-	hypothetical protein	NA	NA	NA	NA
WP_044378032.1|104143_104722_+|protease	snapalysin family zinc-dependent metalloprotease	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP010849|5706444:5756901|DBSCAN-SWA
CATGACGACCTTGATGTTCATCCTCGGCATAGTCGTCTTCGCGGTCGGCCTGCTCGTCTCGATCGCCTGGCACGAGCTGGGCCACCTCTCCACGGCGAAGATGTTCGGCATCCGCGTGCCGCAGTACATGGTCGGCTTCGGCCCGACCCTGTGGTCGCGGAAGAAGGGCGAGACCGAGTACGGCGTCAAGGCCATCCCGTTCGGCGGCTACATCCGCATGATCGGCATGTTCCCGCCCGGCGCCGACGGCCGGCTGGAGGCACGCTCCACCTCCCCGTGGCGCGGCATGATCGAAGACGCCCGATCGGCGGCGTTCGAGGAGCTGAAGCCGGGCGACGAGACGCGCCTGTTCTACACCCGTGCCCCGTGGAAGCGGGTCGTCGTGATGTTCGCCGGCCCGTTCATGAACCTGATCCTGGCGGTGGCGCTGTTCTTCACCGTCCTGATGGGCTTCGGCATCACCCAGCAGACCACCACCGTCGCCTCGGTCTCCCAGTGCGTCATCGCCCAGACCGAGAACCGCGACGACTGCAAGAAGACCGACCCGGCCTCCCCGGCCGCCGCCGCGGGCCTGGAACCCCGCGACAGGATCGTCTCCTTCGACGGCGTCCGCACCGACACCTGGGACGAGCTGTCCGACCTCATCCGCGCCAACCCGGGCGAGGAGGTGGCGATCGTCGTCGAACGCGACGGCCGCGAGGTGACCCTGCACGCGGAGATCGCCACCAACAAGGTCGCCAAGAAGGACGCCGCCGGGCAGATCGTCGAGGGCGAGTACGTCACCGCCGGCTTCCTCGGCTTCAGCTCCGCCACCGGCGTCGTCAAACAGGACTTCGGCGAGTCCGTGACGTGGATGGGCGACCGGATCGCCGAGGCCGCCGACTCCCTGGCCGCCCTGCCCGGCAAGATCCCCGCTCTGTGGGACGCGGCCTTCGGCGACGGGCCACGCGAACCCGACTCCCCGATGGGCGTGGTCGGCGCCGCCCGCGTGGGCGGCGAGATCGCCACCCTGGACATCCCGCCGACCCAGCAGCTCACCATGTTCATCATGCTGGTCGCCGGCTTCAACCTCTCGCTGTTCCTGTTCAACATGCTGCCGCTGCTGCCGCTGGACGGCGGCCACATCGCGGGCGCCCTGTGGGAGTCGCTGCGCCGCCACACGGCCCGGCTGCTGCGGCGCCCGGACCCGGGCCCCTTCGACGTCGCCAAGCTCATGCCGGTGGCGTACGTGGTGGCCGGGATCTTCGTCTGCTTCACGATCCTGGTGCTGATCGCGGACGTGGTGAATCCGGTGAGGATCTCCTAGCGCCGGGCACTGGACACCTCGCGTTCACGGCGGCCCGGCACACTACTGCGTCGGGCCGCCCGCCGTTGGAGGGGGTTCCCCGGGCGTGGTGTGCCCGCGCCGGGACACGTGCCGTAATCTCGAAGGCCGGAGCCCGCCCGCTGACGGGACCGGACCTTGATCCACGACTTGGGGTTGCACAGCAGATGACTGCGATTTCTCTCGGCATGCCGTCCGTTCCGACCAAGCTCGCCGAGCGCCGCAAGAGCCGGCAGATCCAGGTCGGGTCCGTGGCGGTCGGCGGGGACGCGCCCGTGTCGGTGCAGTCGATGACCACGACGCGTACGTCGGACATCGGGGCCACGCTCCAGCAGATCGCGGAGCTGACGGCGTCCGGCTGCCAGATCGTCCGGGTGGCCTGCCCCACGCAGGACGACGCCGACGCGCTCCCGGTCATCGCGCGCAAGTCCCAGATCCCGGTCATCGCGGACATCCACTTCCAGCCCAAGTACGTCTTCGCCGCGATCGAGGCGGGGTGCGCGGCGGTGCGGGTCAACCCGGGCAACATCAAGAAGTTCGACGACCAGGTCAGGGAGATCGCCAGGGCGGCCAAGGACCACGGCACCCCGATCCGTATCGGGGTCAACGCGGGCTCCCTGGACAAGCGGCTGCTGCAGAAGTACGGCAAGGCGACGCCCGAGGCGCTGGTCGAGTCGGCCCTGTGGGAGGCGTCCCTCTTCGAGGAGCACGACTTCCGCGACATCAAGATCTCCGTCAAGCACAACGACCCGGTCGTGATGATCGAGGCCTACCGGCAGCTCGCCGAGGCGTGCGACTACCCGCTCCACCTGGGCGTCACCGAGGCCGGTCCCGCCTTCCAGGGCACCATCAAGTCCGCGGTCGCCTTCGGCGCCCTGCTCTCCCAGGGCATCGGCGACACCATCCGCGTCTCGCTGTCGGCCCCGCCGGTGGAGGAGGTCAAGGTCGGCCTCCAGATCCTCCAGTCGCTGGGCCTGCGCCAGCGCGGCCTGGAGATCGTGTCCTGCCCGTCCTGCGGCCGGGCCCAGGTCGACGTCTACAAGCTGGCCGAGGAGGTCACCGCCGGCCTGACCGGCATGGACGTCCCGCTGCGCGTCGCCGTGATGGGCTGCGTCGTCAACGGCCCCGGCGAGGCCCGCGAGGCCGACCTGGGCGTCGCCTCCGGCAACGGCAAGGGCCAGATCTTCGTCAAGGGCGAGGTCATCAAGACCGTCCCCGAGTCCAAGATCGTCGAGACGCTCATCGAGGAGGCCATGAAGCTGGCCGAGCAGATGGAGAAGGACGGCGTGGCCTCCGGCGAGCCGTCGGTGTCCGTCGCCGGCTGACCCCTTCCGTCCCTCCCGCGCCGCCCCCTGGGGGCGGCGCCGCCGTTTTATGGCAGGTACAGTGCGGAAATCAGCGACCTTCGAGGTGAGGCCCCGCACCGTGTTGACGCAGACCACCTCCCGCGTGCTCGAACCGGCAGACCTGGACGCCGCGCTCGCCGTCCTCGACCGCGAGCCGGTCGCGAACGCTTTCGTGACCTCCCGTGTGCAGGTCGCCGGCCTCGACCCGTGGCGCCTGGGCGGCGAGATGTGGGGCTGGTACGAGGACGGCATACTGACGTCCCTGTGCTACGCGGGCGCCAATCTCGTCCCCCTCTGCGCCACCCCGCGTGCCGTCCGCGCCTTCGCGGGCCGGGCCCGCCGCGCCGGCCGCCGCTGTTCCTCCATCGTCGGCCCCGCCCGGCCCACCGCCGAGCTGTGGCGCCTGCTCGAACCCGGCTGGGGCCCCGCCCGCGAGGTCCGCCCCCACCAGCCCCTCATGATCACCGACCGGATGCCCGCCGGTGTCGCCCCGGACCCCTACGTCCGCCGCGTCCGCAAGGACGAGATGGAGACGATCATGCCGGCGTGCGTCGCGATGTTCACCGAGGAGGTCGGCGTCTCCCCGCTGGCCGGCGACGGCGGCCTGCTCTACCAGGCCCGGGTCGCCGAGCTGGTCGGCTCCGGCCGCTCCTTCGCCCGCTTCGACGCCGACGGCAAGGTCGTCTTCAAGGCCGAGATCGGCGCCGTGACCGACCGCGCCTGCCAGATCCAGGGCGTGTGGGTGGCCCCCGAGTACCGGGGACGGGGCCTCGCGGCCCCCGGCATGGCCGCCGTCCTGCGGTACGCGCTGACCGAGGTGGCCCCCGTTGTGAGCCTGTACGTGAACGACTTCAACACCCCCGCCCGCCGCACCTACCGCAAGGTCGGCTTCCAGGAGGCCGGCGCGTTCATGAGCGTGCTGTTCTGACGAGCGGGGACTTCGCCGCCATGCGCCCGGCGCACGCGGGTAGGCTCCCCGCCATGGACCTCGCGATCGGCCCCCTGGACCTGCCCGCCCACGTAGACGAAGCCCTCGCGGTCCAGGCCGCCGCCTTCGGTCTGGGTCCCGACGAGGTCGCCGTACGCCGTCAGATCGTCCTGCGCCACATGACCTACCCGGGCGCCCGCGCCCTCGGCGCCACCGTCGGAGGCGACCTCGTCGGCTTCGTCTACGGCATGCCCAACGACCGCACCCACTGGTGGTCCACCGTCGTCGAGCCCTACCTGCGCGCCCAGGACCACGAGGAGTGGCTCGACGACTCCTTCGTCATCACCGAGCTGCACGTCCACCCGCACCACCAGAACCGCGGCATCGGCCGCGCCCTGATCACCGCCATCACCGACGGCGCCGCCGAGCCCCGCTCCATCCTGTCGGCCATCGACACCGAGAGCCCGGCCCGCGCCCTGTACCGCTCCCTCGGCTACCGGGACCTCGCCCGCCAGGTCGTCTTCCCCAGCGCCGCCAAGCCCTACGCCGTGATGGGCGCCCCCCTCCCGCTGCGCAGGCGCTGACCTCCCGGCCGATTTCCGCCGCGCCGGACCGCCCGGCTAACCTCGTTTGCCATCACCCTCCCCCAGGCTCTCGGCGCCGCTCGAGCGAGGGGGACCCCCAGCAGCAGGAGATACGAGAACCATGGCGAACGCACCGGTCCAGCGCATGTCCCAGTTGTTGGCGAAGACGCTGCGCGACGACCCGGCGGACGCCGAGGTCCTCAGCCACAAGCTGCTGGTCCGCGCCGGCTACGTCCGCCGCACCGCCGCCGGCATCTGGACCTGGCTGCCGCTCGGCAGGAAGGTCCTCGCCAATGTCGAGCGGATCGTCCGCGAGGAGATGGACGCCATCGGCGCCCAGGAGGTGCTGCTCCCCGCCATCCTGCCCCGCGAGCCCTACGAGGCGACCGGCCGCTGGGACGAGTACGGCCCCGAGCTGTTCCGCCTGAAGGACCGCAAGGGCGGCGACTACCTCCTCGGCCCCACCCACGAGGAGATCTTCACCCTCCTGGTGAAGGACCAGGCGTCCTCCTACAAGGACCTGCCGGTCATCCTGTACCAGATCCAGAACAAGTACCGGGACGAGGCCCGCCCCCGGGCCGGCATCCTGCGCGGCCGGGAGTTCCTGATGAAGGACTCCTACTCCTTCGACGTCGCCGACGAGGGCCTCGCCGAGTCCTACGCCCTGCACCGCCAGGCGTACCAGCGCATCTTCGAGCGCCTCGGTCTCGACTACCGCATCTGCGCCGCCACCGCCGGAGCCATGGGCGGCTCCAAGTCGGAGGAGTTCCTCGCCCCGGCCGACGCCGGCGAGGACACCTTCGCCGACTGCCCGCACTGCGACTTCGCCGCCAACACCGAGGCGATCACGTACGAGCTGAAGCCGGTGGACGCCGCGGAGGTGCCCGCCGCCGAGGACATCCCGACCCCGGACACCCCCACCATCGAGACCCTCGCCGCAGCGCTCGGCGTCCCGGCCTCGGCGACCCTGAAGAACCTCCTGGTCAAGGTCGACGGCGAGATCGTCGCCGTCGGCGTCCCCGGCGACCGCGAGGTCGACATGGACAAGGTCGAGGCCCACTTCGCCCCGGCCGCCGTCGAGATGGTCACCGAGGTGGACTTCGCCGCCCGCCCCGACCTCGTCCGCGGCTACGTCGGCCCGCAGGGCCTGGAGAAGGTCCGCTACATCGCCGACCCGCGGGTGGCCCCGGGCACCGCCTGGATCACCGGCGCCAACAAGCCCGGCACGCACACCAGGAATGTCGTCGCGGGCCGCGACTTCGAGGTCGACGAGTACGTCGACGTCGTGGTCGTCCAGGAGGGCGACCCCTGCCCGAAGTGCGGCACCGGCCTCAAGCTGGACCGCGCCATCGAGATCGGCCACATCTTCCAGCTCGGCCGCAAGTACGCCGACGCCCTGAAGCTGGACGTCCTCGGCCAGAACGGCAAGCCGGTCCGCGTCACCATGGGCTCCTACGGCATCGGCGTCTCCCGCGCCGTCGCCGCCCTCGCCGAGCAGCACGCCGACGACAAGGGCCTGGTCTGGCCCAAGGAGGTCGCCCCGGCCGACGTCCACGTGGTCGCCGCCGGCAAGGCCCTCCAGACCGAGGTGGCGCTCGACGTCTCCGGCAAGCTGGCCGCCGCGGGCCTGCGCGTCCTGGTGGACGACCGGGCCGGAGTCTCCCCGGGCGTGAAGTTCACCGACGCCGAGCTGATCGGCGTGCCGGCCATCCTGGTCGCCGGACGGCGCGCGGGCGAGGGCGTCGTCGAGCTCAAGGACCGCCGCACCGGCGAGCGCGAGGAACTGCCGGTCGAGGAGGCCATCGCCCGCCTCACGGCCTGAGCGGACGCGACACGGGGGCCCGCCCGCGCCGTGCGGGCGGGCCCCCGTGTCGCGCTCCGGGACCCGTGGTGACGGCCCGTCGACTCTTCCCGGGCAGGCGGGGGCCGGACCTCCGCGGCGGGCCCCTACAGCCGGCCCGCGACTACAGCCGGCCCGCGACTAGAGCCAGCCCGCGAACTCCAGCAGCAGCTCCGCGTCCTTCTCCCGGCCGACCCTGCGGGCCCGTACGCCCGACTCCACCGCCCGGAACAGCGTCCAGCCGCGCAGCCGTTCCTGGTCGACCTCCAGCGACTCCGCGAGCCGCTTGATCCGCCGCCGCGTGGTCGCCGCGCCCGACGGCTGGGCGATCAGGTCCTCCACCCGGTCCCGCACCAGCCGCGCCAGGTCGAAGGCGCTCTCGCCGACCACCGGATCCGGCCCCACGGCCAGCCACGGCATCCGGTCCCCGGCCAGCACCTTGCTCTGCCGGAACGTGCCGTGCAGCAGGACCCCTTCGGGCGGCCGGACCAGCAGCTCCTCACGGATCGCGAGCGCCGCCTCCACCAGCGGCGCCACCTCCGGATCGGCCGCGGCCCCCGAGCGCATGGCCTCGGCCTGCCGCCCGGTCCGCTCCGCCACCGTCTCGAACCGGTGCCCGGCGGGCGGTTCCACCCACAGCCGCCGCAGCGTGCCCGCCGCCTCCAGCAGGGCCTTGGCCTCCGGGAGCGACCGCACCGACACGTCCGGGTGCAGCCGTTCCAGCAGCAGGACGCCCTCGGTCGGGTCCGCCTCGTCGAGCACCTGCACCGCGCCCCGGCCGCCCCAGTGCGCCAGCGCCACCCGCTCGCTCTCCGGACGCGCCCGCGGCGGGGCCAGCTTCAGCACGGCCGGCGACCCGTCCGCCCGTCGCACCAGCACGACCAGGCTGCTGCGCCCGCCGGGCACCTGCACCCGCTCGACGGTCAACTCGCGTAGCGCGACGGCCCGCCGCGCCAGCTCGGGCAGTCTCTCCAGCCAGCCGTCACCGTCCGGTGCCGTCTCACCGAGCGCCCTGACCAGGCGCCGCGGCGGTTCGAATGCCATGCGCGAGCCGTTCCCTTCCCGTACGTGTCCGTCCCGTCGGTGCCGTCCCGGGCCCCCGAGTCCCGCGGGGCCCGCCCCGTGGGCGTCCTCCCGTGTCCGTCACGCCGGCGGTGACGCCGGGGCCGACGGGCCGGCGGCACCGACCCGCTCGGCGAGACCAGGGAAGGCTACGCTCCCGCCCCGCCAGCCGACGGCACGGACCGCCGCCTCCCGCAGCGCGTCCGCCGCCGCGGCCCGCCGCTCACCGGCGGCGGCGCGCACCAGGTCGGAGTAGACACCGGCGACCCTGTCCTCCAGCTCGGCCGCCAGCCGCACCGCCGCGGCCGCGTCCGGCACCGGGAAGGGCAGCGCGTAGCCCGCGGCCGCGGCGACCGGCTCGCCACCCCGGGCCCGCACCTGCCGCACCAGCGCGTCCCGGCGCGCCCGGTGCGCGTCGAAGGCCGCGCGCGCCTGAGCGCGCCGCTCCGCGCCGATCCGGCCGCCCACGACTCCGTAGCCGTACACCGCCGCGTGCTCGGCCGCCAGCGCCGCCTGGAGGGCGTTCAGCTCCGGTTCCCTCGCCTCGCTCACCCGTGGTCCTCCGTCAGCAGATACACATGTGCCGCCCCGGCCGCCGCCACGGAGGCCAGCAGCCGCGCCAACTCGCCCGGTACGTCCGCCAGTGCCCCGGTCCGCCGCGCGGTCAGCTCCCGCTCGGCCGCGGCGAGCCCGGCGAGGGCGTCCTTCTCGTTCCCCGGCACGGCGGCCGGCGGGGAAACGGCGGGTGACGCCTGGGCCGGGGAGGTCCGCGGGGCGGGCGCGGTGCCGCCGCCGAACGCCTCCGCGTGCCGCACGACCTCCTCCCGCAACGGCCGCAGCCGCGCGGCGAGCCCGGGATGGGCGGCGATCACCGCGTCGTACCGGGCGGCCAGCCGCTCGCTGTCGCGGGCGGCACGCGCGCGTACCCGGGCGGCGGCCGACGGGCTGCCGCCCGTGCCGTCGGACCCGGGCCCGGCCGAGCAGCCCGCGAGCAGGGCGGCCCCGGCGGCGGAGGCGAGCAGGCTCCTTCTGCGCGGCCCCGGGCGGGTGCGCGGCGATGAGGTGAACGGCGGCACGGCGGACGTCCTCGGGAACTCGTACCAAACGAATAGCTGAAAATATGCGACTGAAAATACGAAGCGAACGCGAGAAAAGGGGAGTTGGCAGGGATCGAAAGACGGCAGGGAACGAACCGGAGCGACTCGAAGCGATCGGGACGCGAAACGGCCCGTCCGTGATCACGGTACCCGGGCACCCGCCCCGCACCACTCAGCGGCACCGCTCGCCGCGGCCGCGCTGCCCGGGTGGACGGCAAGGTGGACGGCAACACCCTCCCGGACCGGATACCCTTTGACCAGACACGCGACCATCCCACAACAGCACACGCGGCCGAGGAGTCACCCGGATGAGCACCACCCAGAGCGAGAGGCTGCGAGAACTGCTGGAACCGCTCGTCACCTCCCAGGGTCTGGATCTCGAGGAGATCGCGGTGGACTCGGTCGGACGCAAGCGGGTGCTGCGCGTCGTCGTCGACTCCGACACCGGTGCCGATCTGGACCGGATCGCCGATGTGAGCCGCGCGCTCTCGGCGAAGCTCGACGAGACGGACGCGATGGGCGAGGGCGAGTACACCCTCGAAGTGGGAACCCCGGGCGCGGAACGCCTCCTCACGGAACACCGGCACTACGTGCGCGCCACCGGCCGGCTGGTGAAGTTCCAGCTCACCGAGGGCGGCGAACTGGTGGCCAGAATCCTGACCGTCGACGGCGACGGTGTCGACGTCGAGGTCCCCGGGGTCAAGGGGCGCAAGCCCACCGCACGCAGACTCGCCTTCGGCGACATCGCCCGGGCGCGCGTGCAGGTCGAGTTCAACCGCAAGGACGACACGTCCCACAAGAAGGAAGAGGAGGCGTAGCCGTGGACATCGACATGAGCGCCCTGCGGGGCTTGGTACGGGAGAAAGAGATCTCCTTCGACCTGCTGGTCGAGGCGATCGAGTCGGCCCTCCTCATCGCCTACCACCGCACCGAGGGAAGCCGCCGGCACGCGCGCGTGGAGCTCAACCGGGAGACCGGGCATGTGACCGTGTGGGCGAAGGAGGACCCCGAGGACCTCGAAGAGGGCCAGGAGCCCCGCGAGTTCGACGACACCCCGTCCGGCTTCGGCCGTATCGCCGCCACCACCGCCAAGCAGGTCATCCTGCAGCGGCTGCGCGACGCCGAGGACGACGCGACGCTCGGCGAGTACGCCGGCCGCGAGGGCGACATCGTCACCGGCGTGGTCCAGCAGGGCCGCGACCCGAAGAACGTCCTCGTCGACATCGGCAAGCTGGAGGCCATCCTGCCCGTGCAGGAGCAGGTCCCCGGCGAGACCTACCCGCACGGTATGCGCCTGCGGTCGTACGTCGTACGGGTGGCCAAGGGCGTCCGCGGCCCGTCGGTGACCCTGTCCCGGACCCACCCCAACCTGGTGAAGAAGCTCTTCGCCCTGGAGGTGCCGGAGATCGCCGACGGGTCCGTCGAGATCGCCGCGATCGCCCGTGAGGCCGGTCACCGCACCAAGATCGCCGTCCGTTCCACCCGCTCCGGACTGAACGCCAAGGGCGCCTGCATCGGCCCCATGGGCGGCCGTGTGCGCAATGTCATGGGCGAGCTGAACGGTGAGAAGATCGACATCGTCGACTGGTCGGACGACCCGGCCGAGATGGTGGCGCACGCCCTCTCGCCCGCCCGCGTCTCCAAGGTGGAGATCGTGGACATGGCGTCCCGGTCCGCCCGCGTGACCGTGCCCGACTACCAGCTCTCGCTGGCGATCGGCAAGGAAGGGCAGAACGCCCGGCTGGCGGCCCGGCTGACCGGCTGGCGCATCGACATCCGCCCGGACACCGAGCAGCAGGCGGAATAGCCCGGCTGCCGGCCGGGAAAGAGATCGTTGGGCCGACCGGGGAATAGATCCGGGCCGTGGAGCGATGAGATCACGACAGCTTCCAGCGCGCCACGTGTTCGATTCGTCCCCCGAAGGGGTGAGGTCGGCCCGGGGAGGTAGACTGAGAAGTGTCTGGCCGGACGCCAGCCCGCGCATGCCCAGAACGCACCTGTGTGGGGTGCCGGGAGCGAGCGGTCAAGAACGAGCTGCTGCGGATCGTGGCGGTCGAGGGCGCATGCGTCCCCGATCCTCGCGGTACGCTGCCCGGCCGGGGTGCGTATGTGCACCCCGCCACGGTCTGTCTCGACCAGGCGGTACGCCGCCGGGCGTTCCCGCGGGCACTGCGCGTCCCGGGACCGCTCGACGCAAAGGCGTTGCGCCATCACGTCGAGCAGGCACAGGGTTGCTGAAGGCAACCTGGTAAGGAAGACGTGCCGCACGGAACCCCGTGCGGTCTGGTACCTCGCGAGTCGAAAGCAGGTCGAGATTGCGATGAGCACTCGATGAGTACGCGATGAGTACGCCCATGAACTAGCGACGGTCCGGCCGCAACCCGGACCTCAAAGGAGCGAAGTGGCTAAGGTCCGGGTATACGAACTCGCCAAGGAGTTCGGTGTGGAGAGCAAGGTCGTCATGGCCAAGCTCCAGGAACTCGGTGAATTCGTCCGTTCGGCGTCTTCGACGATCGAAGCGCCTGTGGTACGCAAACTGACTGACGCATTCCAGCAGGGTGGCAACGGCAAGTCCGCCGCCAAGCCCGCGGCCCCGAAGAAGGCCGCCCCCAAGCCCGCCGCGCCGGCCCCGGCGCAGGCGGCACGTCCGGCTGCCCCGCGGCCGGCAACCCCCAAGCCCGCGGCTGCCCAGCAGCCCGCGGCTCCGTCGGCGCCCGCGCCGGCCACCCCGGGTCCGCGCCCGACGCCGGGCCCCAAGCCCGCGCCGCGCCCGGCCCCCGCGGCTCCGGAGTTCACCGCTCCGCCGTCCGCCCCGGCTCCGGCAGCGCCGAAGCCCGCAGGCGCCCGTCCCGGCGCGCCCAAGCCCGGCGGCGCCCGTCCGGGTGCCGGTCAGGGCCAGCAGGGCGGCCAGGGCCGTCCCGGTGGCCAGGGCGGTGGACGCCCCGGCGCCTCCGCGCCGCGTCCGGGTGCCCGCCCGGCCGGTCCGCGCCCGGGCAACAACCCCTTCACCTCCGGTGGCAACGCCGGTATGGCGCGCCCCCAGTCGCCCCGCCCGCAGGCTCCGCGTCCGGCCGCGCCCGGCGGCGCCGCCGGTCCGCGTCCGCAGGGTCCGGGCGGTGCCCAGGGCGGCGGTCCCCGTCCCCAGGCTCCGGGCGGCTCCCGTCCGACCCCGGGTTCGATGCCGCGTCCGCAGGGTGGACCGCGTCCCGCCGGTCCCGGCGGCCCGCGTCCCAACCCCGGCATGATGCCGCAGCGTCCCGCTGCCGGCCCGCGTCCCGGTGGCGGCCCCGGTGGCCGTGGTCCGGGCGGTGCGGGCCGTCCCGGCGGTGCCGGTCGTCCCGGCGGTGGCGGCGGCTTCGCCGGCCGTCCCGGTGGCGGCGGCGGTGCCGGTCGTCCTGGTGGCGGCGGCGGTTTCGCCGGCCGTCCCGGTGGTGGCGGCGGCTTCGGCGGTGGCGGCGGTGGCCGTCCCGGCTTCGGCGGTCGTCCCGGTGGTCCCGGTGGCCGTGGTGGCACGCAGGGCGCCTTCGGCCGTCCCGGCGGTCCCGCGCGTCGCGGCCGCAAGTCGAAGCGGCAGCGCCGTCAGGAGTACGAGGCCATGCAGGCCCCGTCGGTCGGCGGCGTGATGCTGCCTCGCGGCAACGGCGAGACCATTCGCCTGTCGCGCGGTGCGTCGCTCACCGACTTCGCGGAGAAGATCAACGCCAACCCGGCGTCGCTCGTCGCGGTCATGATGAACCTCGGCGAGATGGTCACCGCGACCCAGTCCGTCTCCGACGAGACGCTGGAGCTCCTGGCCGGCGAGATGAACTACACCGTTCAGATCGTCAGCCCGGAGGAGGAGGACCGCGAGCTGCTCGAGTCCTTCGACATCGAGTTCGGCGAGGACGAGGGCTCCGAGGAGGACCTGGTCGTCCGTCCGCCGGTGGTGACCGTCATGGGTCACGTCGACCACGGTAAGACCCGGCTGCTCGACGCGATCCGCAAGACGAACGTCATCGCGGGCGAGGCCGGTGGCATCACCCAGCACATCGGTGCCTACCAGGTCGCGACCGAGGTCAACGACGAAGAGCGGAAGATCACCTTCATCGACACCCCGGGTCACGAGGCGTTCACCGCCATGCGTGCCCGCGGTGCGCGGTCGACGGACATCGCGATCCTCGTGGTCGCGGCCAACGACGGTGTGATGCCGCAGACGGTCGAGGCCCTGAACCACGCCAAGGCGGCCGACGTGCCGATCGTGGTCGCGGTCAACAAGATCGACGTCGAGGGCGCCGACCCGACCAAGGTGCGCGGCCAGCTCACCGAGTACGGTCTGGTGGCCGAGGAGTACGGCGGCGACACCATGTTCGTCGACATCTCCGCCAAGCAGGGGCTGCACATCGACTCCCTGCTGGAGGCCGTCGTCCTCACCGCCGACGCCTCGCTCGACCTGCGGGCCAACCCGAACCAGGACGCGCAGGGCATCGCGATCGAGTCCCGTCTGGACCGCGGCCGCGGTGCCGTGGCGACGGTCCTCGTCCAGCGAGGCACGCTGCGGGTCGGCGACACGATGGTGGTCGGCGACGCCTACGGCCGTGTCCGCGCCATGCTCGACGACAACGGCAACAACGTGGCCGAGGCCGGTCCGTCGATGCCGGTCCAGGTCCTGGGTCTGACCAACGTCCCGGGCGCCGGCGACAACTTCATCGTGGTCGAGGAGGACCGTACGGCCCGCCAGATCGCGGAGAAGCGTGCCGCCCGCGAGCGGAACGCCGCGTTCGCCAAGCGCACGCGCCGCGTCTCCCTGGAGGACCTGGACAAGGTGCTCAAGGCCGGCGAGGTCCAGCAGCTCAACCTGATCATCAAGGGTGACGCTTCCGGTTCCGTCGAGGCCCTGGAGTCCTCCCTGCTCCAGCTCGACGTCGGCGAAGAGGTCGACATCCGCGTCCTGCACCGCGGCGTCGGTGCGGTCACGGAGTCCGACATCGACCTGGCGATGGGCTCGGACGCCATCGTGATCGGCTTCAACGTGCGCGCCGCCGGGCGTGCCGCGCAGATGGCCGAGCGCGAGGGCGTGGACGTCCGGTACTACTCGGTCATCTACCAGGCGATCGAGGAGATCGAGGCGGCCCTCAAGGGCATGCTCAAGCCGGAGTACGAGGAGGTCGAGCTCGGCACGGCGGAGATCCGCGAGGTCTTCCGTTCGTCCAAGCTGGGCAACATCGCGGGTGTGCTCATCCGCTCCGGCGAGGTACGCCGCAACAGCAAGGCGCGCCTCATCCGCGACGGCAAGGTCATCGCGGAGAACCTCAACATCGAGGGTCTGCGTCGCTTCAAGGACGACGTCACCGAGATCCGCGAAGGCTTCGAGGGCGGTATCAACCTCGGAAACTTCAACGACATCAAGGTCGACGACGTCATCGCGACGTACGAGATGCGCGAGAAGCCGCGGGCGTAACCTCCGGCTGACGGTGGGCACTGGCCGACGGGACATCGTTCCCGTCGGCCAGTGCCGCGTCCCCGGGCGTGCGCGGGGCGGGCGGAAACTCCGTCGAGCCCCCGGACGCGTTCGGGGTACCGTTCTTGATGTCCCTGTCCATACGGATGGCAGGGCCATCGATCCCGTACCGGCGGGTGAACCGGTTGCACATGTATGTGGGGACGCTGTCCTTCGACCTCCTCCTCGGCGACGTACATTCGCTGAAGGAGAAGCGCTCCGTCGTCCGCCCGATCGTCGCCGAGCTCCAGCGGAAGTACGCGGTGAGCGTCGCCGAGGTCGACCATCTGGACCTCTACCGCAGGGCCGGCATCGGCCTCGCGGCGGTCTCCGCCGACGCGGGGCACCTGAGCGACGTACTGGACCGGTGCGAGCGGCTGGTCGCCGGCCGCCCCGAGGTGGAACTGTTGTCGGTCAGACGGCGCTTCCACGGCGACGACGACTGACGACCGAGCCGACCCAAGCACGAAACGAAGAGAAGAAAGAACGGGAGACGGACCAGTGGCCGACAACGCGCGGGCTAAGAGGCTGGCGGACCTCATCCGAGAGGTGGTGGCCCAGAAGCTGCAGCGCGGGATCAAGGACCCGCGGCTCGGCTCTCACGTCACCATCACGGACACCCGGGTCACGGGTGACCTCCGGGAGGCGACCGTCTTCTACACCGTCTACGGGGACGACGAGGAGCGCCAGGCCGCTGCCGCCGGTCTGGAGAGCGCCAAGGGCATCCTGCGCTCGGAGGTGGGCCGGGCGGCGGGCGTGAAGTTCACGCCGACCCTCACCTTCGTGATGGACGCCCTGCCGGACACCGCCCGGACCATCGAGGACCTCCTCGACAAGGCGCGGCAGTCCGACGAGAAGGTGCGCGAGGCGTCCGCGGGCGCCTCCTACGCCGGTGGGGCCGACCCGTACAAGAAGCCCGCAGACGAGACGGACGACACCGCCGAATGACCGCCAAGCACACCCCGCCCGACGGCCTTGTCATCGTCGACAAGCCGTCGGGCTTCACTTCGCACGACGTGGTCGCCAAGATGCGGGGCATCGCCCGGACGCGGCGCGTCGGGCACGCCGGCACCCTCGACCCGATGGCGACCGGTGTCCTCGTCCTCGGCGTGGAGAAGGCCACCAAGCTCCTCGGGCACCTCGCCCTCACCGAGAAGGAGTACCTCGGCACCGTCCGCCTCGGGCAGACGACGATCACGGACGACGCCGAGGGCGAGATCACCGCGTCCACCGACGCCTCGAAGGTCCGGCGCGAGGACATCGACGCCGGGGTCGCCAAGCTGACCGGCGACATCATGCAGGTGCCGTCCAAGGTCAGCGCCATCAAGATCGACGGCGTGCGGTCCTACAAGCGGGCCCGGGAGGGCGAGGAGTTCGACATCCCCGCCCGGCCCGTCACCGTCTCCTCCTTCGCCGTGCACGACGTCCGCGACGCCGTCGCCGAGGACGGCACGCCGGTGCTGGACCTCGTGGTGTCGGTGGTCTGCTCCTCCGGCACCTACATCCGCGCCCTCGCCCGCGACCTCGGCGCGGACCTGGGCGTCGGCGGCCACCTCACCGCCCTGCGCCGCACCCGCGTCGGCCCCTACAAGCTGGACGCGGCGCGCACCCTGGACCAGCTCCAGCAGGAGCTGACCATGCTGCCGCTCGCCGAGGCGGCCGACGCCGCGTTCCCGCGCTGGGACGTGGACGACCGCCGGGCCCGGCTGCTCGTCAACGGGGTGCGGCTGGAGATGCCCGACGCGTACGCGGGTGCCGGCGCCGTGGCCGTCTTCGGCCCCGAAGGCCGCTTCCTGGCCCTCGTCGAGCACCAGCGGGGCAAGGCCAAGAGCCTGGCCGTCTTCGGCTGAGGCGCACCCGCCCGCCGTCCTTCCCGTGGAGCGGCCACGGGGATGTCCCCGCCGCCGCTCCACGGCCCCCCTCGGTTCCCCCACCCTAGGGTGTATCCATCGCCCCCGTTCTGTTCACCCGTTCGGGCAGGCGCTCGGAGTGAACCGGGGGAGCGCAAGGGGGCGCGTTCGCCAGGTGATCTTTCCTGGCCGAGCACCGCCCGCCTAACGTCGACCCAGGGCACGGTGTGCGACGGTGTACGGCGGGGAGGTTCGGCGATGGCGTCGAGGAACCGGTCCCGGGACGCACGCGGCATCCGCGCCGCGGACCGGGAGCCCGAGGCCCACGCCCCCGACGACGTCCTGGTCCGCATCCACGACCCGGGCGGCCGCCTGCTGGGCACCGGCTTCGTCGCCGACCACCACGGCACGGTGATCACCAGCCATGAAGCGGTCCACGGCCTGACCCGCCTGATGGTGCGCACCGCCCGGGGCGGCGTCCGGGAGGTGTCCGCCGACGAGGTGATGCCGCTGCCCCACCGGGACCTGGCCCTGGTACGCACCAAGGGGCTGGGCGTCCCGCCCCTCCCGGTCACCGTCCGGGAGCGCATCGAGCCCGGCACCTATGTGCGGATCGCCGCGGGCGGCTGGCGCGAGGCGCGGATCCTCGGGACCACCGAGGTGACGTACGCCGCCGCCGACCGCCGCCGCCCGCTCGGCCCGGCCCTGGAACTGGCGGTCGGCACGGCGGGACGGGACGCGCTGGCGCCGGGCGGCGGCGCGGCCGGCGGGCCGGTGGTCGACGCCGCGACCGGCGCCGTCGTCGGCGTCCTCGGCACCGCCCTGCGCGCCGGGCGCCGCGAGGCGGGCTTCGCCGTGCCGCTGCTCGCCCGGACTCCCGGCGACACCGCGGCGGGGCACCGCGCCGACGGGCCGCTCGCCGACCTGCTCGCCGAGAACGCGGCGACGGTCCCGGCGCACGGCGCCGACCTCAATCCGGCGGGCGTCGTCGAACTGACGGCCACCTCGGTCGGCCAGGACAGCCCGCCCGGTCCCCTGGGCGCGGGCGCCCCCGCCGCCGAGCCGGTCGCGCGGGCCGCCGTGCTGCGCGAGCTGACCGCCTTCCTCGACGGCCCGGCGCCCGTCCTCGGACTCGTCGGGGCGCCCGGCAGCGGCCGTACGACCGCACTGGCCGCCCTCGCCGCCCGCCGCGCCCCGAACGCGGCACCGGTGCCCGCGCTGTGGCTGCGCGGTGCCGATCTGCGCGAGACCGACGCCTCGGTCGCCGACGCCGCGCGCCGGGCACTCGCCCGGGCCGCCCGCATCGTCGGCGCCTCGGAGCGCCCCTTCCCCGGCGGCCCGCAGGACGCCACCCCCGAACGGCTGGCCCGCGTCGCCCGCGCGGCCGGCTGCCCCCTGCTGCTCCTGCTCGACGGCCCCGAGGAGATGCCGCCGCTGCCCGCCCCGCGCCTGTCCGAGTGGGCCGAGGGGACGGCGAGGTGGCTGCGGGAGACGGGTGCACGGCTGGTGGTGGCCTGCGGGGTGGAGTACTGGGAGCGCGCGGGAGCGGAGTTCGGGCGGGGGACGCTGTACGGGGGCAGGGGCGGGGCTGAGCCCGAGGGCGGGATCGGCGGAGTGCCGGCGCCGACGTCGGGGGCGGGCGCCGGTGGGGGAGGACGGCCGGACGCGGACGGTGGGGACGGCGGCGGGGGAGAGCGGTCTTCGGCTGCCGGTGGGGAAGGGCCGCCGGAGACGGTGGACGCCGGCGGGCAGCGGCGGCCCCCGGCCGTCGCCGGTGGTGCTCGCGCCGCGCACGAGGGAGGCGCGAGAGCCGTGACCGCCGCCCTGCCGCCTTGGGTGGCGCTGCGCGCCCTGCCGCCCTGCGTCCCCCTCGGTGACCTGACGGAAGAGGAGGCCCGGCAGGCGCGCGCCCGGTACGGCGTCCCGGAGGACGCCCTGCCGGAGGCGGACGCACGGCACCCGCTCACGCTCCGGCTGCTGTCGGAGGTGTGCGCCGCCCTCCCCGGCGCCCCGGACCCGGCCCGCGTCGACCGGGACGAGGTGTTCGCGGCCTACCTCGACCTGGTCTGCCTGCGCATCGCGGTCCGCCTCGCCGCCCACAACGGCCTGCGCGGCACGGCCGTACGCCGTCTGGCGGCCAGGGTCGCCGGACAGGTCCACGAGGCCGCCCGGCGCAGCCTCGCCGCCGGGCAGGGCGCGCTGGACCGCACCGGCTTCGAAGCGGTGTTCCCCTGGGGGCAGGCGCCGGCGCGGCTCGGCGGCGGCACCGGCTGGGCCACGGCCGTCCTCGCCGAGGGCCTTCTCGTCCCCGCCGGCAACGGCTACCGGTTCGCCCACGAGGAGCTCGCCGACTGGCTCCAGGGCATCCACCTCGACCTGGACGAAGCGCTGGGCGCCCTGGTGCACACCGGCGCCCGCCCCGTTCCCGTACCGCACCACCGCATCGGCCCCGTCGTCCAGGCGATGCTGCACCTGGCCCGCCACCCGGGCAGCCGCCACCTCGCGGCCCGCCTGGGAGAGCTGGTGCACGCCCTGGAGGCCGACCCGCACTCCTGGTGGGCGGCGCGGCTGCTGGGCGAGGTGCTGCCGCGCGTGCCGGACGCGTCGCCGTACACGGAGGTCCTGCGGCTGCTCGCCGACCGGATCGCGGCCTGGCGCGGAGCGGGGCGCCCCGTGCCCCGGGAGTTGGGACCGGACTTCTGGACCGCCCTGGCCCTGCCCCGCGAGATCTGCGCGGACCTGCTGCGCCGGCTGATCCTCGCCGACGGGCCTCCGCACCGACCCGGGCCCCGCTACCTCGACACCGCGGCCCGGCTGCTCGACGACGACCCCGCGACCGTGCAGCCGCTCCTGGTCCGCTGGTTCGACGACGAACGGCCCCTGCCCGGGGCCCCGCACGCCACCGTCGCCACGGCCGCGCAGGCCCTGCTGCACACCCGGCGCCGCCTCGCCCCGGACGCTCTTGTCGAGGTGCTGGCCGACAGCACGCACCGGCGCTCCGGCGAACTGCTCACCGTCCTGGCCGAGGAGGAACCGTCCGCCGTCTGCCGGGCCGTCGGCCGGTGGGCACACGACGCGCGCCCGGCCCGGCGGATGGCGGCGGTGACGTACGGGCTGCGCGCCGCTCCGTACGTACACTCCGCCGCCGACCGCGACCTGCTGCGCCAGGCCGCCCTCCGCCTGCTCGGCGACCCCGGGGAGGCCGCCCCGCACGGCGGCGCGCTCGCCCTGCTCGTCCAGGACCCGGCCGTCCGCGGGCGGTACCTCGACCCGGCACTGCGGCTCTTCGCGGCCGGCGACCCCTGCCTTCCGCCGCGGGCGATGGCCGCCGCCCTGCCCACCCACCCGGAGCCCGTCCTCAACGCCTTCCGGGCGCGGCTGGCCGGCCCCGACGCGGGGGAGGCGCTGCGCAGACTCGCCGACGCGGCCCGGCCCGGGCTCGTCGGCCGGATCGCCGCCGTCATCGGGGAGGCCGTGACCGAGCGCCCCGGGATTCTCCGCCACCTGGCCGCCTACGTCGCACAGCGCCTCGATCGCGAGGAGACCGGCCAGGCCACCGCCGCCCGCGCCGCACTCCCGCCCCTGGTCACCGCCCTGCTGGACAGCGGCTCCGAGCCCGTACGGGCCGCCCTCGCCACCGTGCTCGGCGGTGCGGGCACCTCCGCCTCCCGTCCGCTGCGCGGCGAACTCCTGGAGTTCCTCCTCGCCCGTGAGCGCGACCCCGCCGTGCTGGACGCCCTGCTGCGCGCCGCCGCCCGGCGCGACGGTGACGACCTGCGCGGCCTGCTGCACCGCACCGCCTTCCTCCTCGTCCGCACCCCGGACGGCGCCGCCCGCTTCGACCGGGCCCTGGTCGACCTCGGCCGCCATGTCCCCGGCTTCGCCGCCCGGGTGACCGGCTGGCTGGCCGAGGTGCCGGGGGAGTGGGCGGTGCTGGTGGGGCCCGGCACCCGCCGGACCCTGGAGGACCTGGCGGACGCCCCCCTCCCCGCCTGACCGGACCCCTGGTCCGGTTGCGTGCACCCGGTCACACCACCCATGCCGGTGCGGGCGAGAGGGGCACGGCATGGCACCCTTAGACCTGCGTAGAGGCGTAATTCACGGACACGGGTTCGACGAGTACTCGACAAGGAGCAGTCACAGTGCAGCGCTGGCGTGGCTTGGAGGACATCCCCCAGGACTGGGGGCGCAGCGTCGTCACCATCGGCTCCTACGACGGAGTGCACCGCGGGCACCAGCTGATCATCCGGCATGCCGTGGACCGCGCCCGCGAGCTGGGCGTGCCCGCCGTCGTCGTGACCTTCGACCCGCACCCCAGCGAGGTCGTGCGCCCCGGCAGCCACCCGCCGCTGCTCGCCCCGCACCACCGCCGTGCGGAGCTGATGGCCGAGCTGGGGGTGGACGCCGTCCTCATCCTCCCCTTCACCACCGAGTTCTCCAAGCTGTCCCCGGCCGACTTCGTCGTCAAGGTGCTGGTCGACAAGTTGCACGCCAAGGCCGTCGTCGAGGGCCCCAACTTCCGCTTCGGCCACCGGGCCGCCGGGAACGTGGAGTTCCTCGCCGAGCAGGGCAAGACCTACGACTTCGAGGTCGAGGTCGTCGACCTGTACGTGACCGGCCGGGCGGGCGGCGGCGAGCCGTTCTCCTCGACGCTGACCCGGCGCCTGGTCGCCGAGGGCGACGTCGCGGGCGCCGCCGAGATCCTCGGCCGCCCGCACCGGGTCGAGGGCGTGGTCGTCCGCGGCGCCCAGCGGGGCCGCGAGCTCGGCTTCCCCACGGCCAACGTGGAGACCCTGCCGCACACCGCCATCCCGGCCGACGGCGTCTACGCCGGCTGGCTGCACGCGCAGGGCGAGGCGATGCCGGCCGCCATCTCGGTCGGCACCAACCCGCAGTTCGACGGCACCGAGCGCACGGTGGAGGCGTACGCCATCGACCGCGTGGGGCTCGACCTGTACGGGCTGCACGTCGCGGTCGACTTCCTGTCCTTCGTCCGGGGACAGGCGAAGTTCGACACGCTCGAGGCGCTGCTGGAGCAGATGGCCGCGGACGTCGAGCGCTGCCGCCGGTTGGTGGCCGAGGCCGGGAAGCCCGCCTAGGACCTCTCGTCCGGTCCCGCCGGGCCGGTCCGGCCCGGTCCGGACGACGGCGCTCGGCCACTCCCGGCGCGCGCCCAGTGGCACGCCACCTGGGCCGTCCCGCTTCCGTCGAGGATCTCCGGGTCCCGGTCGCGGCAGGCGCCCGCGACACCGGCCCGCTCGGCCGCGCCGCTCGCCAGGACCGGGCAGCGGACGTGGAAGCGGCAGCCGGCCGGGACGCGGGACGGGTCCGGGGGCTCACCGGTGAGGACCACCGGGTCGCCCGGGGCCTCCGGCAGGACCGACAGCAGGGCTTGGGTGTACGGGTGCCGGGGCGCCGTCAGCACCTGCTCCACCGCGCCCGTCTCCACGATCCGCCCCAGGTACATCACCGCGACCCGGTCGGCGATGTTCCACGCCAGCCCCAGATCGTGGGTGACCACCAGCGCGGAGAGCCCGAGTTCGGTGCGCAGCCGCAGCAGCAGGGCGAGGATCTCCCCGCGCACCGAGGCGTCGAGGGAGGCCACCGGCTCGTCGGCGACGAGGAGTTCGGGCTCCAGGACGAGCGCGCCCGCGATGACGACCCGCTGGCGCTGGCCGCCGGACAACTCGTGCGGGTAGCGCAGGAAGAAGCGCTCCGGGGGCCGCAGCCCGGCCCGGGCCAGGGCCCCGGCGACCGCCGCCCGCTCGTCACCGCCGTAGCCGTGGATGCGCAGGCCCTCGGCGACCGCGTCGTAGACCGTGTGCCGCGGGTTGAGCGAGCCGCTGGGGTCCTGCAGCACGAGCTGGACGCGCTTGCGGTAGCTCCTCAGCGACCGGGCGGAGTACTCCAGCGGGCGGCCCTCGAAGGTCACCTGGCCGCCGGTCGGCTCGACCAGGCCCAGCAGACAGCGGGCCAGCGTGGTCTTGCCGCAGCCCGACTCGCCGACCAGGGCGACGATCTCGCCGGGGCGGATGTCGAGGTCGACGCCGTCGACCGCGCGGGCCCGGGGGGCGCCGTGCCGGCCGGGGAAGGCGACGCGCAGGCCCCGGGCGCTGAGCAGGGCGGCGGTCTCGGTGCCGCCGGGCGCACCGGGGGCGGCGGGGGAGGTGGTCATGGGGCGGCGCGCCTCGCTTCCTCGAAGTCGTCCGGCTCCGGGGCCGGCTCCCCGGCCACCCGCACACACGCCGCCCGCCGGTGCGCCCCGGCGTCGCGCAGCACCTGGTCCTGGGTGGCGCACGACTCCAGCGCCACCGGGCACCGCGGGTGGAACGCGCACCCGGGCGGCACGGCCGCCGGGTCCGGCGGATCGCCCGCCAGCCCGCGCGGCGCGAACCGCGAGGCCGGATCGCCGATCCGCGGGAACGCGGCCGACAGGGCCTGCGCGTACGGGTGCCGGGCGTCCTCGTACACCTGCCGGGCCGGGCCCTCCTCGACCACCCGCCCCGCGTACATCACGGCGAGCCGGTCGCAGGTGTCGGCGAGGACGGCGAGGTCGTGGCTGATCATGATCAGGCCCAGGTCCTGCTCGGCGACGAGCTGTTCGATCAGCCGGAGGATCTGCGCCTGGACCATCACGTCGAGCGCGGTGGTCGGCTCGTCGGCGACGATCAGCCGCGGGTCGCAGGCCAGCGCCATCGCGATCATGACACGCTGGCGCTGCCCTCCGGACAGTTCGTGCGGGTAGGCGCCGGCGCGGGCGGCGGGCAGGCCGACCTGCTCCAGCAGTTCGCCGGTCTTCCTGCGGGCCCCGGCCGGGGTGGCCTTGCCGTGCAGCAGGATCGGCTCGGCGATCTGGTCGCCGACCCGGTGCACGGCGTTGAGGGAGTGCATCGCGCCCTGGAAGACGATGGAGGCCCCGGCCCAGCGGACCGCCCGCACCCGGCCCCACTTCATCGTCAGCACGTCCTCGCCGTCGAGCAGGATCTCCCCGGTGACCCGGGTCCCGGGCGGCAGCAGCCGCAGCAGCGCCAGCGCCAGGGTGGACTTGCCGCAGCCCGACTCCCCGGCGATCCCGAGCTTGCGGCCCGCCTCCAGGCGCAGGCCGACCCCCCGGACCGCGGCCGCGCCACCGGCGTACGTCACCGTCAGGTCCCTGACGTCGAGCAGGCTCACCGCCCCACCCCCAGCCGGGGGTTGAGGACGGACTCCACGGCCCGTCCGCACAGTGTGAACGCCAGCGCCACCAGCGCGATCGCGACGCCCGGCGGCACCAGATACCACCAGTGCCCGGCACTGACCGCGCCCGCCTCCCGCGCGTCCTGCAACAGCCCGCCCCACGAGACCACCGTCGGATCGCCGAGGCCGAGGAAGGCGAGGGTGGCCTCGGCGAGGATGGCCGAGGAGATGATCAGGGTGGTCTGGGCCAGCACCAGCGGCATGACATTGGGCAGGACGTGCCGGGTCATGATGTGCCGGTGCCCGCCGCCGAGCGCCTTGGCGCGTTCGATGTAGGGCCGTGTCTCCACCGCCAGCGTCTGCGCGCGCACCAGCCGGGCCGTCGTCGGCCAGGTCGTCACGCCGATCGCCACGACGATCGTGGTGAGCGAACGGGACATCACGGTGGCCAGCGCGATCGCCAGCACCAGCGTCGGCATCACCAGGAACCAGTCGGTGATCCGCATCATCACCGTCGCGTACCAGCCGCCGAAGTGCCCGGCCGTGACCCCGATCAGCGTGCCGATCGCGACCGAGAGCACCGCGGCGAGCAGCCCCACCAGCAGCGAGACGCGCGCACCCCACACCAGCAGCCCGAGCAGGTCACGGCCGAACTGGTCGGTGCCCAGCGGGAACGCGGCACTGGGACCCTGCAACGGGCGGCCCGGCGCGTCGGTCACGTTGCTCACGCCGGAGCCGACGAGCAGCGGCGCGGTCAGGGCCAGCAGCGCGAAGAGCACGAGGGCGGCCAGGCCGAAGAGACCGGCCCGGTGGGTGCGGTACTGCCGCCAGAAGCGCGCGGCGGAGGCGCGGCGCCGCCGCCGGGCGAGGGCGCGCGGACTCGTGGTGGTCGTCTCGGTCGTCATCGGCCCACCCGGGGGTCGAGCAGCGGATAGATCAGGTCGGCGAGCGTGTTCATCAGGATCACCGCGGCGGCGAAGACGAAGAACAGTCCCTGCACCAGCGGCAGATCGGGCACGCTCAGCGCCTGGTAGAACAGCCCGCCCAGGCCCGGCCAGGAGAAGACGGTCTCCACCAGGATCACGCCCGCCACGGTCCGGCCGAGGTTGATGAAGACCAGCGTCACGGTGGGCAGCAGGGCGTTGGGGACGGCGTGCCGCCGCCGCACCAGATCGTCCCGCAGCCCCTTGGCGCGCGCGGTCGTCAGATAGTCGCTGCCCATCTCGTCCAGCAGCGCCGACCGGGTCACCAGCAGCGTCTGCCCGTACTCCACCGCCACCAGCGTCATCACCGGCAGGACCAGGTGGTGCGCCACGTCCACCACGTACGCGAAGCCCTCTTCGCCGCCCGACTCCATGCCGCCGGTCGGGAAGAGACCGGGCAGCGGGCCGGCGCCCACCGACAGCACGATGATCAGCAGCAGCCCCAGCCAGAAGGAGGGGATGGAGTACAGCGTCAGCGCGAGGCCCGTGTGCAGCCGGTCGCCGAGCCGTCCGTGCCGCCAGGCCGACCGCGTGCCGAGGAAGACGCCCAGGGCGGTGTAGAGGACGAAGGCGGTGCCGGTCAGCAGCAGCGTGTTCGGCAGGGCCTCGGTGATCTTGTCGAGGACCGGGGTGTTGAACTGGTAGGACGTCCCGAGGTCGCCGGTGAGCGCCTTGCCGCAGTACTCGGCGAACTGCTGCCACAGCGGCAGATCGAGCCCGAACTGCTCGCGGTAGGCGGCCAGTTGCTCCGCCGACACCGGGCGTCCGCCCGTCATGTACTTCACCGGGTCGCCGGGGATCAGCCGGAACAGGAAGAAGCTGGTGACGAGGACGGCCAGCAGCGAGACGGCCGCGCCGGCCACCTTGCCCGCCACATACCGCGGATACGCCCCGCGCCCGCGCCCGCGGGACGCGGCCGTCTCCGTCCCCCCGGCCGGCGCGGGTGACGCGTCCGCGGTCACGAGTACCCGGTCGCCCGTCTGGTCGCGGTCCATCGCCGCTCTACTCGCGGTCCTCGGCGGTGGCCCGGCGGCGCATCGCCGCGAACCCCCCGAGCGCGGCCAGCACCACGAAACCCCCGGCCACCCCGAGGACCACACCCGTCGAGGACGAACCGCCGGAGGAGTCCCCGGACTCCGCGGGGACCGCCGACCACCAGCTCCAGTAACCGTCCTGGCCGTAGATGTTGCCCGCCTTCGCCGGCATGGTCGTGATCGACTCGATCTGGTCCGTGCGGTACGCCTCGACCGCGTTGGGGTAGGCCATGACGTTCATGTATCCGAGGTCGTACAGCCGCGCCTGCATCTGCTTGACGAGATCCGCCCGCGCGGCGGGGTCGTACTCGGCGAGCTGCCGGGCGTAGAGCTCGTCGTACCGCTTGTCGCAGATGAAGTTGTCGGTGGCCCCGGTGTCCTTGGGCGTGGCCGGGAGCGCCGCGCAGGTGTGGATGGACAGCACGAAGTCCGGGTCGGGGTTGACGGACCAGCCGTCGAAGGCGAGGTCGTACTTGCCGGCCAGCCACGGGTCGGTGACGTTGTCCAGGCAGTCCAGCCGGACGCCGATGCCGAGCTTGCCCCACCACTCCTGGAGGTACTTGCCGACCGCCTTGTCGTTCGGATCGGTGGCGTGGCACAGGACGCGGTAGGTGATCGGTTCGCCGTCCTTGCCGACGCGCCTGCCGTCGCCGTCGAGCCGGTACCCGGCCTGGTCGAGCAGCCGGGCCGCCTTCGCCGGGTCGTACGCCAGCTTCCGGCTCGCCGACGGCTTCCAGAAGTACTGCGAGAAGCGCGGCGGGATGTAGCCCTCGCCCTCGACGGCATGCCCCCGGAACACCTTGTCGATGATGGCCTCGCGGTCGACGGCCATGAACAGGGCGTGCCGCACCTGCTGGTCCAGCAGGGACGGGTGGCCGTCGCCGAACGTCCGGCCGTTCTTGGCCCTGGCGCCCGGATTGGTGGCCAGGGCGTAGAAGCGGCGGCCCGGGGCGTCGTTGACGCGGATGTTCCGCTCGCCCTCCAGGGAGGCGGCCTGGGCCGGGGTCAGGGAGGGCGACCCGGCGACGAAGGACACCTCGCCCTTGCGCAGGGCGGAGACGGCCGCGTCCTGGTCCTTGTAGTAGCGGAAGACCAGCTCGTCGAATTTGGGCGCGCCGCGCCAGAAGGTCTTGTTGGCCTTGAGGCGGACATAGCTGTCGGCCTTGTAGTCGGTGAGGACGAACGGCCCGTTGCCGACGACGGGGAAGCTCGAGTCGTTGTTGAACTTCGAGAAGTCGCCGACCTTCTCCCAGACGTGCTTCGGCACGATCGGCACGTCCAGCGCGGTCATCGTGGCCTGCGGCTTCTTCAGCTCGATGACCAGCTTGGTCGGGCTCGCGGCGGTCACCTTCCTGAAGTTGCCGACGAAGCTGCCGTTGGCGGTGGCCGCGCCCTGGTCGGTCATCATCTTGTTGAACGTCCAGGCCGCGTCCTCGGCGGTGACCCGCTTCCCGTCCGACCACGTGGAGCCGGAGCGGATCGTGTACGTCCAGGTCAGCTTGTCCGGCGACGACTCCCACTTGGTGGCCAGGCCCGGGACGGCCCGGGCGTCCTCGGGGTCGTAATTGGTCAGGAACTCGTACATCAGCCGCTGGATGCTGGTACTGAGCAGGCGCACCGCCAGGAACGGGCTGAGCGAGTCCACGCTCTGCGCCACCGCGACGGTCAGCACCTTCTCGCCGTCACCGGCCGCCCGTGCCTGCGCGGGGGACGGGTTCAGCGGAGTCGCGAGTGAGGCGGTGAGGGTGAGCGCCGCCGCCCCCGCGCCCGCGAGGAGCCGGACGCGGCCCGGAAGGCTGCGTGTCTGTGTGTCCATGGGGTCGGTGACCTCGCGTCATCGCTCGCAGGGGACGGACGGGTTGATCAGGTGCCGATGGATGATGAGTGTGTCTATCAGCGGCTTGTGCACGCGTCAATGGCGCGTCCACCCCGTGTGGCCTGCGAAAACAACGAATCGAGGACCATTTTTCAGCCATTGGTCGAGACCACTGACGCCGCGCTGGCCAGGGCCTGACGCCGACCGCCCCGGCCGCCCTCCCAAGACGGAGAAGGCCCGGGGCCCGTACCGCGGAAGGCGGTAGGGGCCCCGGGCCGAAGGGCACCGGTGATCCGGCGCGCGCTACTGCTGGGGCGGCAACTGCCCGGGCGGCATCCCCGCTCCCGGCTGCTCCCCTCCGGGCGGGCCGTAGGGGTTCGGGGCGTACCCGGGCTGAGGACCGGGCTGCCAGGGCTGGCCGGGCTGGGCCCCGGGGTGTCCCTGGAACGGCTGCCCGCCCGCGGACGGATACCCCGGCATGGGCGGAGCCATGGTGGGCGGCGGATTGCCGTCCGAGGTCCACAGCCCCTGCTCCTGCTGGGCCCGCACGAAGTCCTCGGCCACCTTCGCGGCCAGGTCGAAGTACGCCTCGCGCACCTTGGGCCGCATCATGTCGAGATCGACCTCGGCACCGGCCGCCAGATGCTCGTCGAACGGTACGACGATCACACCCCGGCAGCGCTGCTCGAAGTGGGTGACGATGTCCTCCACCTTGATCATCTTGCCGGTCTCGCGCACCCCCGAGATCACGGTGAGGGACCGCGAGACCAGGGACGCGTACCCGTGCGCGGACAGCCAGTCGAGCGTCGTACTGGCGCTGCTCGCCCCGTCCACCGACGGCGTGGAGATGATGATCAACTGGTCGGCGAGGTCGAGCACCCCGCGCATGGCGCTGTAGAGCAGTCCGGTACCCGAGTCGGTGAGGATGATCGGGTACTGCCTGCCCAGCACGTCGATCGCGCGCCGGTAGTCCTCGTCGTTGAACGTCGTCGACACGGCCGGGTCCACGTCGTTGGCGATGATCTCCAGACCGGAGGGCGCCTGCGACGTGAAACGGCGGATGTCCATGTACGAGTTGAGGTACGGGATCGCCTGGACGAGGTCACGGATGGTGGCACCGGTCTCCCGGCGCACCCGGCGGCCCAGCGTGCCGGCGTCCGGGTTGGCGTCGATGGCGAGGATCTTGTCCTGCCGCTCGCTGGCGAGCGTCGAGCCGAGAGCCGTCGTGGTGGTCGTCTTGCCGACGCCGCCCTTCAGGCTGATGACGGCGATCCGGTAGCAGGAGAGCACCGGCGTGCGGATGAGCTCGAGCTTGCGCTGCCTCTCCTGCTCCTCCTTCTTGCCGCCGAGCTTGAACCTCGACCCGCCGGGGGTGGGGCGGCTGCTCTTGGCCTTCTGCCTCTTGGTGTTCACCAGCCGGTCGGAGGTCAGCTCCACGGCGGCGTTGTAGCCGAGCGGCGCGCCCGGGCTGATCTGCTCCCGCTGGTCGTGCTGGACCGCCTGCGGCCAGGGGGCACCGGTACGGGGGTCCACACCGGGCTGGCCGGACGGCTGCGCGTACGGGTGCTGGGCGTGCGGCGGCTGCCCCGGCACCGGGGGCTGACCCGGCTGCGGCTGTGCCGGCTGCGGCTGTCCCTGCGCCGGGGGCGGCAGGGGCTGACCGGGCCGGCCGGGCTGCGCGGGCGGCTGCTGGGGCTGCTGGGGCTGGGCGAAGGGGGGCTGCTGCGGGTAGCCGTAGCCCGGCTGCGGCGGCTGGGGCACCGGCTGCTGCGGGTAGCCGTAACCCGGCTGGGGCGGTTGCGGGTAGCCGTACCCGGGCTGCGGGGGCTGGGGCACCGGCTGCTGCGGGTAGCCGTAACCGCCCTGCGGGGCCGACGGGGGGAAGCCGTAACCGCCCGGCGGAGCGGGGGGCTGCCCGGGAGCGGCCGGCCAGCCGCCCGGCGCGGGCTGCGGCGCCTGCGGCGGGGCCGCGGCGGCCGGTGGCTGAGCGGGCGCGGACGGGTCGGCGGGCTGTGCCATGGGCGGCTGCGGCTGTCCGGCCGCCGCCGGCCACCCCGGCGCGGCCGCCGGCGCCCCGCCGGTGGCCGCCGACGGGAACTGCGGCGGGAGCGGCGGAACGGCCCCCTGCGGCGCGGGCGGAGGCCGCCAGCCGGACGACGCGTCCTGCTGCGGGCTCTCGGTCTGCTCCGGTGCGCCGCTCGGCGCGGCCGGGGCGTCGCCCGCGGGCTCGGCGTCCTGGGCCTCGCCGTCGTCGCCCGGGTCGGCCGCCGGGCTCGCGCCGTCCTCCGGGCCTGGTGCGGCCGCCCCCTCGCCGTCCTGCGGCTCCGGCCGGGACGCGGCACCGTCGTCCGTGCCCTGCTCCGTCGTCTCCTGCTCGCCGGTGCCCGACGCGGCTTCCGCGCCGCCCGGGCCGGCGGACGGCTCCGCCTCGCCCGGCGCCTGCGCGCCGCCGGGGGCAGGAGCGGGCGCGGCCTCACCGGCGGACACCTCGCCCGCCGCCGGGGCGGTACCTTCCGGGGCACCGCTCGCCGCGGCGCCGGAGGCATCCGAGGCGGCGGAGGTGACGGGAGCCCCGGAGGGCGCGAGCGGGAAGGAGCCCGGCGGGGGCGGGGGAGCCGCGATGGGGCTGCCCGTGGGCGGAGGAGGCGTCACGCCGCCCGCACCCGTGGCCGGTCCGGACCCGGAGCCGGGCAGCGGACCCGGGGCGGGCACCTGACCCTGGCCGGGAACGTGACCGCCGGCAGCGGGAGCCTGAACCTGGCCGGGAACGTGACCGCCGGCACCCGGAGCCTGACCCGGACCGGGGACCTGTCCCTGGGCGGGAACGGGGCCGGGAGCCGGCGCGACGGCGGGCGGGGCCGCGGGCGCGGGCGGAGCCGCCGGGCCGGAGTCGCCGGACCCGGTCGTGTCGGTGGGACCAGGAGTGTGCGCAGGGGCGGGCGCGGGCGCGGCCTGCTCCCCGCCGGTCGACGCGCTCTGCGTGTACCAGGCGGGCGCGGCGTAGTCGATGGTGAACTCGCCCGTCGTCTCGACGGCGGCTTCCGCGTCGGACTGGTCATCGCTGGGCGTGGTCCAGCCCACGCGCATCCCGTCCCGATCGCTGTGCACAATTCCTCCTGGTGTGGTCGAGCACCCTCGTGCCGTACGGGCACTCATGTGCCGGGCTGGGGGCGACCGTTCCTGTTGTCCGATCGGTCTGGTTCGGCCCCGGACGCGAACAACCCACCCGTGGGTTCCGGCGTCGTACGCTCATCAAGCGTAAACGCCGCGGACCGCCGGGGGGCAGGCCCGTCCGCCGTGCGCTCGCCCCGTGCGACCGCCGCCCTCCCGGGCGCCGTCCGCCCCCGCTGCCGCAGGCCTTCCGAACCCCGGCGGTCCGGTCTCTCCGCGGCCCGAAGCCCGGCCGTCCCGCGCTACTTGGCGGCGAGCCCTCCGTTGTGCGGTGCGGGCTCCAGGTCGAACTCGCCGTCGCGCGCGCCGAGTACGAAGGCCCGCCACTCCGCCTCCGTGTAGCGCAGCACGGTGTCCGGATCCAGGGAGGACCGCATGGCCACCGCCCCGCCCGGAAGGTAGGCGATCTCGACGCGTTCCTCGTGCTCCTCGGTGCCGGGCGCGCTGTGCCACTCGACATCCGAGATGTCCAGTGCGTACAGCTCGTCCCGTTCCCTCTCCTTTCGAGCCCTGACGTCCTCGTCCTGCGTCCCCGCAGTGCTCTCCTGTACGTCAGCCATGGTCAACGGGCCCCTTCCGGTGAGCGAAACGACATGCACGGTCACCTTACTGGCCCCGGTCGGCGCGCACGGTCGAACCGGACCGCCGCCAAACCCCGCCCGGCGCCGCCGCGTTCGCCGTACCAAGAGCCCTGCCGCTCGCCGGGGGCCGGCGCGTCCACTCGCGGCCGTCACCGTTCATCCCTGAGAGTGGGCCGCCGCCGGTGACGGGTGCGCCACCGGGGCGGGGGCGACGGCGGCTCAGTCCATGCGGCGCGGGGCCCCGAGGAGACCGGTCTCCGCGTCGGTGGGCTGGGTCATCACGTACTGCCGGTGCTTCTGCGTGCACCACAGGGCCACGTTGTCGGAGAGGGACGGCAGGGAGACGATGTCGTCCCGGCCCAGCCGCATCACCTTGCCGACGATGTCGGCCTCCTGCGGGGAGATCCGCTGCACCCCGACGACGTCGGCGGTGGACAGCAGCCGCGGCGCGGTGGGGCCGAGGTAGGGGAGCAGGGTCAGCACCGACTGCCAGGGCGCCGTGGTCAGGCGGCTGCGCGGCGGGCGGATGCCCAGGTCGCGGATGATGAGCACCGGGCTGGCCGGGGACGGGCCCTGCGGGGCGATCCGCCCCACCTGGTGCACCGTCACGCACTGCTGGCCGCCGCCGGCCGCCTGCGCCATCGGCGACCACAGTTGCGGACGAGCCGTCTCCACGGCCACGCGGGCGCCGATCGCCGCCGCGCGCAGGGCGATGACCTGGGCGATCCAGGTGCCGCCGACCAGCACCACGTCCAGCCGGGTGGGCCGGCACAGGCCCAGCACCGCGGGCTGGTTGTCGGGGTCGATGCCGAGGACGAGGCCGTCGTCGCCCATGGGCAGGGTGAGCTGGGAGAGCACATCGGCGTCGACGAGGTGACGCTCACGCCGGGGGCCGAGCAGACCGAAGGCGGCGCGCATGCGTCGCTGCGGGCCGTGCCGGGAGGGTTCGGGGTTGCGGGGCAGATGACCGGGACGCTGCCCGGGGAAGCCCGGCGTCGAGGAGCCGAAGCCGGGGCGGCCGGTGGCCGGAGCGGTCGGGGCGGACATCAGCGAGTACCTCCCAGCGGCAGGGTGGCCAGAACTCCGGGCAGCTGCTCCCGGTCCAGCCGTACCAGACCGATCTTGAACGCGGAAGCCGCCCGCTCCAGATGCTGGACCGCCTCGTCCAGCCCGTTCTCACCGCGGCCGGTGAGACGCACATGCCCGGACAGGGCCAGCACCCTTCCCCTCCGCTTGCTGATGGTGAGCGAGAAGGTGCTGGCGAGGGCGGGGGAGGAGGTCAGCGCGCCGACGAGCTGGGGCAGCGCCGGGGCGCCGCCGCCGAGCTGCGGCCAGCGGGAGATCCAGTACGTGGTGTGCCAGCGGTCGTCGCACCGCCACGCGCGGGAGGTCTCGGCGGTACGGCGCGTGGAGCGGCTGCCGTCGAGCGCGGCGCCGCCCGTGGTGGCCAGCGGGTTGACACAGCTGGAGGTGGCGATGGCCGCGACGACCTCCGACTCGCTGAGCACCTTGGCCTGCAGGCCCGCCCCCATGAGACGGCTGGCCAGCTGGTCGGCGACGCGCAGCAGTGCCCGCCGGGCGCCCTGCATGCCCCCGCCGCGGGCCGCCACGGCCTCCGGGCACAGCTCCGGATCGAGCTTGAGCGCCACCCAGGTCAGCCGCAGCCCCGGCGTCATGCTCTGCGCCTGCAGCGGCCCGTAGGAACGGACCGCCATGGCCTGCGGCGGCAGATGCGGGGCCGGCGCGGGCTGGGTGTGCTGGACGACCTGGACCGAGGCGAGCCGGATGTCGTCCACCTCGAGCAGGCCCTGGATCAGATCGAGGGGGATGTCCCGGCTGCCGTGGGCGGGACGCAGGGGGATGTCCGCGGCCTGCACCTGCACCAGCGCGGTGAGGAAGGTGCCGTCGCCGACCATGCCGACCTCGCGCTGCTCACGGTCGTGGAAGGCGTAGGTGCGCAGCGCCGGGTCGCACTCGACGGCCGGGGCGAAGCCGGGGTCCGTGCCGGGCGGGACGGGCTCGGCGTTGCGCTTCCTGCGGTCCCGCAGGGCACGAGCCGTGGTGAACCACTCGGGCAGCGGCCGGCCGCGCCGGCGCAGCAGACCCGCCAGGACCAGTGGTACGGCCAGCACGATGCCGATCGTGAGACCGATGGGGCGCAGGAGCCAGCCGATCAGGACGACCGCGGCGGCCAGTTCGAAGCCGACCAGTTGCTGGACGCGGATGGGGCCGATGCTGCCGGGGCGCCGGGCGAGCGACGGCGCGGCCGGGCTCACACGAGCGGGGTTCGCGGACCGCTGTGCCGGTTCCGGTTGCCCTTGGTTCTCCTGCGTGCGACGGCTGCCGTTTCGGCGCCGGGACCTGGTCGCAGTGCTCATCCCCCGGTACAACCCCTTTGCATTGTCTGGCCGCGACTTGAGCTGGCGGCGCACCACGGTACCCCGTACCGTACGGTGCGATCGTCACACGGCATAGTAGGGGCCCCTGCAGGAGCAAACGCCGCGTAGTGCCGGGCGATCCTGGGGAGTTCCGACTACGGCAACAAAGCGAAAAAACGGGGAGTTGACCCATCGATGGCGACACGTCGGGATGAGCTGAACGCCTACTCCTTCGCGCGCAGGCGCACGGTGGCGGCGTTCCTCCAGCCGTCCCCGCACGGTTCGGAGGAGGCGGCCCCCCGCCCCTTCAAGACCGTCCTGCCGAGCCTCGGCCTGGCGACGCTGGTGGTCATCGGGTTCGGCGCGTGGGGCATGCTCAGCCCGACCGCGCCGAAGGGCTGGGACGAGGAGGGCAAGAACATCCTCGTCGGCAGCGAATCGACGACGCGCTATGTACTGGTGCGCACCAAGGGGGAGGAGAAGCCCAGCCTCCACCCCGTCCTCAACCTCGCTTCGGCCAAGCTGCTGCTGAAGGGCGAGAGCCCGAAGGTCATCAAGATCAAGGAATCGGTGCTCGACGAGAGCAAGTACCCGATGGGAGCCACCGTCGGCATCCCCTTCGCACCGGACCGGCTCCCCTCTTCCAAGGACGCGGAGACGGTCAAGATCTGGGCGTTGTGCGAGGCCCCGGGCAAGGGCCAGGACAACCAGCCCGTCCGGGCCACCTACGTGCTGGACCAGAGCGACTACGACACCCTGCTGCACAAGGGCGACAAGGAGCTGAACCAGCACGAGGCCCTGTACATCGAGGCCCCGGCCGCACCCGGCGGGACCGGGCCCCGGTACATGGTCACCGCGGACGGCCGCGCCTACCTGATGGGCGGCAAGGACTGGAAGCTGCGGTCCGAGTCGGCGCTGAAGACGCTGGAGCGCGCCGTGTTCGGTGACGGCGTGACGCCGCAGAAGGTCAGCGCGGAGTTCATCAAGACGCTGAACGTGGTCGGCGCCGTCGACTTCCCCAACCTCGGCTCCGGCGTGGGCGCACCCGCGCAGGTCGTGGGTCTCGATCCGAGCCTGTCCAAGGTGGGCCTCGTCCTGGAGGCGCCCTCCGGCCTCGGGAAGCAGAAGTACATCGTGCTGAAGGACCGGGTGCAGCCCGTCTCCGACTTCACGGCCCAGCTCTGGCTGCGCAGCCCCTGGGTGGAGGGGGTGTACGGGGGCAAGAACCCGGAGCCGGTGGAGGTCACCTTCAACGACATCCAGCCCGCCGACGGCGAGTGGCTGTCGGAGATGAACTGGCCCAAGGAGCCGGTGGCCCAGGCCAACACGCACTGGGAGGCCGGCGGCAACAAGGTCTCCTGCAGCATCTGGCACGGCAAGAAGGACCAGTACACCGGCCTGCCGCAGATGACCGTCTGGAGCGGCCGGGAGTACCCCAAGGACGTCTCCCAGAGCGGCTCCAGCACCTACGTCTCCCCGGGCAGCGGACTGCTGTTCAAGCGGCTGACCGGAACCAGCGCCGGCGGCGGCAACGTCTACCTGGTCACCGACACCGGCCTGCGCTACTCGGTGCCCGCGCGCAACGACAGCCAGGTGACCGGCGGCGAGAAGGCCGACGGGCAGCAGCAGACCAACACCGCGCAGGTCAGGCTGGGTTACGACAAGATCCGCCCGGTTTCGGTGCCGGCGGCCTGGGCGGACCTGCTCGCCGCGGGCCCGGAGCTGAGCAGCGGCAACGCGCAGCAGGCCCAGGGCTCCTGATTCCCGTCCCTGAAACCCGCTCCGCGGACCGCTCCAACTGACTTGTGAACGACCTGGGTTGGCTTCATCGCGATCCAGCTACAGAACCTTTCTGATGTTCGTTCTGTCAGTGGAAGCCACTAGAGTGGGACCCAGATCAGACTGGATACGACTGTCGCCGTGAGGCGGTGGTGTACCGAGTGTGGATCTACCCAGAACTCCTACGTCTCATGGGGGACACAGCATGGCTGGACAGCAGTTCACCATGACCGAGGAGGAGATGATCGCGTTCAGCGGTCGCATCTCCTCGGTCAACTCCTCGATTCAGTCCGAGATCCGTCGCCTGCAGACCGTGATCGACACCATCACGGGCGGCTGGAAGGGCTCGGCGGCCACCGCGTACAACAACCTGCAGTCGCAGGTCAACCAGGATGCGAACAAGATCAACCAGATCTTGAACGACATCAAGGAAGCGATCGACCAGAGCACCAAGGCTTACGCGGCTTCGGAAGAGGAGCAGCGCGCGTCCATCCAGAGCATCGCTGCTCAGTCCCCGTTCGGATGATCGGCCCCGTGCGCCTCGGCGCACGCCCGTGACCGACCATCGACACAACTGAGGAGACACAAGACATGTCCGGGCAGATCCTCGTCAATTTCCAGACGATCTCCCAGGCCGCCCAGGACGTCCGCTCGACCGCGAACAACATTCGCCGTCAGCTGGACGAACTCGAGGCCGGCGTTGCGAAGATCGCCACCAGCTGGGAAGGCCAGGCGCAGGAGGCCTACCGCGCCAAGCAGGCCGAGTGGGACCAGCGTGCCAACTCCATGCAGCAGACGCTCGAGGCCATCGCCAAGGCCCTCGACGGCGCCGCTCAGAACTACCAGGCCACCGAGCAGAAGAACGCCTCCATCTGGGGCGGCTGACGTGATCGCTTGATGGGGGCGGGTGCGCGACGGCGCGCTCGCCCCCATTGGCGGTTGACGGGACATGCGGAACATCCGGTTCGCCACCGGTCCGCACGCCCCGTGCCAGAACGAAACGGGAGGACGTAAGACAGTGGGATCCGGGGCATCGCGCACCGCGCGACGGAGCGCCGCAGGCACCGCCGCCCTGGCGGTCCTCGCCTGTGGGCTGCCCTTCGCGGGCGCCGCGCCGGCCGCCGCCGCGGAGCGCGTGCGGACCACTTTGGCCGACGGCGACGTGCGGTTCCAGATCGACGACACGAGCTGCTCGTTCCCGTCCGACCCCATCAAGGGAACCCCTTGGTCCCTGCAGCGCGTCGTCCTCGACCAGTTGTGGCAGGACACCAAGGGCAAGGGTGTCAAGGTCGCCGTCATCGACACCGGCGTCGACGCCGTGAACCCGCAGCTGAGGCCGGCCGTCGTCAACGGCAAGGACTTCCTGTCGAAGGGCGGCAACGGCAAGACCGACGAGGTCGGCCACGGCACCAAGGTGGCGGGCATCATCGCCGCCCGCAAGTCCGACGAGAGCGGATTCATCGGCATCGCCCCCGAAGCCACGATCATCCCGATCCGTCAGAACGACGACCAGGGCACCGGCAACGTCGGCACGATGATCCAGGCCATCAAGTACGCGGCCGACGCCGGCGCCGAGGTCATCAACATCTCGCAGGACACCGCGTCCAAGATGGACCCGACGGTCCACGCCGCCTTCCAGGCGGTCATCAGGTACGCCCAGGAGAAGGACGCCGTGATCGTCGCCGCGGCCGGCAACAACGGCGCGGACGGCAAGATCAAGGAGACCTACCCCGCGGCGTACCCGGGCGTCCTCGCGGTCGCGGCCTCCGACCGCAACAACGCCCGCGCCCCGTTCTCCCAGTCGGGCAGGTTCGTGGGCGTCGCGGCTCCGGGCATCGACATGATCTCGACGGTCCCCGTGGGCGGCCACTGCGTCGACCAGGGCACCAGCTTCGCGGCCCCGTACGTCTCGGGCGTCGCGGCCCTGATCCGCGCCAAGCACCCCGACTGGACCTACAAGCAGGTCATCACCCAGATCGAGCAGACGGCGGACCGCACCAAGCCGGGCCGCGACGACTTCGTCGGCTGGGGAGTCGTCGACCCGGCCGCCGCGGTCAACGAGGACACCACGGAACCCTCCGAGAAGGGTCCGACACCCGACCCGATCGGCCTCGCGGGCGACTCCGCCGACGTCCAGGCCGCCACCCTGGTCCTCGGCGAATCCCGCCAGGAGCGGATGGAACGGTACGCCCTGTACGTCCTGGCGACCGGCGCCGCCGTGGTGCTCCTGCTGTTCGGAGGCGGACGGGTCCTGAGCGACTGGCGACGCAAGCAGGGCGTGGGCAGCAATGTGGAATCAACGGGGAGTTGAGTATGGCTGAGCAGTACAAGGTCGATCTGAGTGAGATCGAGGGCACCATCACGAGGCTGAACCGTGTCCTGAAGGACATGGGGACGTCGGCTTCGAACTGCAAGAACACGACCTACTTGCCGGCCGGAGCGCTGGGCAAGAACTTCCGAGAGGCCGAGGCGTTGTACAGCGCCCACGAGCAGATGAAGGAACGCCTCTACGAGATCGTCGCCCACCTGGAATCGGTGCTCGACGACTTCGGACAGAAGACGAAGAGGACGCACGACGCGTTCGCCGACGCGGAGGCGCAGAACTACGCCGCCTTCAACAGGAAGTGACACGGTGTTCTGCTGCATGAAGAAGAGGGGGCTGTAGCCATGGGCGAAAAGGGCATCGACAACTTCCAGTACGTCGAGGCGAACCAGTGCTTCGCGGGCGAACACACCACAAAGTTCGGCCTGGAATACGACATGGACCAGATGAAGGACATGGTCCGAGACGCAGACCCGGGCACCGTGAAAAAGGTTGCGCAGGGGTGGGCAGCGCTCAACAAGGACCTCGTCGGAAGCGGCGGGATCAAGGAGACCTTCGACGCCGCCGTCGAGCACGTTCTGGCCCACTGGGAAGGCAAGAGCGCGGACCTGTTCAGGGAACGGGCGCGTATCGTCGGCCAGAAGATCACCGACAGCGCCAAGTACGCCCACTACGCGTCTCAGTCCCTCGAAGGCGCCGCTGAGACTCTTGCAAAGATCAAGCCCATCGTCTTGGCGATGGAGAAGCCGAGCAAGCTGTCGAGCGCGGGTGACTTCATCGGTGATCTGGGCGACCGGGACGCTTCGGGCGCGGACAACGCCCTGAAAAGCGGGGCCAGCTCGTCGGAGGCCCTGGCCAAGAACGAGGGCAGCCTGTCGGCCGGGCGTGAAGCCCAGCTGAAGATGGCCGAACAGATGGAAATTCTGGGGGCCGCCTATAACAGGCGGGCTATGGAGATGGGGTCGTGGAAGCGTACTGGGGGCGTTGAAGATGGGGAAAACTACCCTGGCGACCCCGGCGGCATCCCGCCTGCCGCAGTAGTTGTCCCAACCGGGAACGCGCGGGGGCCGCAGGGAGCTACGGGCGGCAGCCCTCGCGGTGGTCAGGCCGGTACCATCAGCCCGTCGAAGCCCGTCGCCCCGCCTGCGGGCATTACGGGCGGCGCACACAAGCCGATCGCGCCGCAGGCTCCCCAAGTAGGCACAGCGATTGACGGTGTCTCCGGCGGCCGTACTGGGGGACCGTCGGTTGGTGGTCCCAGTACGGCCGGCGGCGGAACCACTGGCGGCAGTGTGCCCGGTGGCAGCGGCGGAGGAATTGTGGGTGCTGTGCCGGGTGCGGCGGGAGCCGGTGCTGTTCGAGGCGGAGCGGGGGGCCGTGCCGGTGCGGGTGGCACGGTCGGTCGCGGTGCCACCGGTGCGGGTGCGGGCGGTATGGCTGGTCGAGGCGCTGCTGGTGCTGGGGCTGGTGCTGCCGGAGGCGCTGCCAAGGGCGGCACGGCGCGCGCGGGCGGCCTGGCTCGCCAGTCCGGTGGCGTTGTCGGTGGCACTCCAAGGACCGGGGCTGGGGCCGGCGCCGGTGCGGGCAGGGGCACTGCCGGCGGTTCGGGCTTGCACCGCAGCCGCGGAGCGGCGGGAGGAGCCAGCGCTGTCCGTAAGGGCGGCATGGTGGGCGTACCAGGAGCACGGAATGGTCGTCATCAGGACGAAGAGCGTCGTGAGGGCGAGCGGCCCGACTACCTTGTCGAGGACGAAGAGACCTGGACTCCGCAGACCAACGCAGCGCCGAGGGTCATCGAATAGTCGCTGACGCTGGATGCTCACCAGCACGTGACAGGATGCGTGGGCGTGGCTTTCGGGCCACGCCCACGTTCGGTAACGCGAGAGGGATGACGGAATGGCCTTCAGGCGAACGATGTGTGGACTGGGCGCCACGGCACTGAGCGGCGCGCTGATCATGGCGGCGGCTCCCATCGCATCTGCCGACCAGACCAGACGTGACCAGTGGGCGCTCGAGACACTTCAGGCAGAGTCCGCCTGGAACATTTCCAAGGGGGAAGGCGTCACGGTTGCCGTGATCGACACTGGCGTCAATGCCCAGCATATCGATCTGAGGCACAATGTTCTCAAGGGCAAGGATTTCATCGACGGTGACGATGACGCCTCGCCTGAGAGTACGGATGCGCAGCCTTCTCACGGTACGGGTATGGCCTCAGTCATCGCAGGGCATGGACATGGCCCGGGTGCTGCTGATGGAGTGATGGGACTGGCACCCGCAGCCAAAATCCTTCCCATCCGTGTGAATCTCGAAGGGAATTCCGGATTCGCGGACGAGATTCATTATGCTGTGGATAATGGAGCCTCGATCATTAATATCTCAATGATCCTCCAGGACTCACAGTATAAGGATGGAGCTTCGGCCGAGGATCTTGAAGCCGTCGCCTATGCCCTTGAAAAAGACGTCCTGATCGTGGCGGGTGCGGGGAACGATGGGAAGGGTGGGGATCTTCCGTTTCCCGCGAACACCCCGGGTGTTGTTGCTGTTGGTGGAGTCGACAGGACTGGGAGCTTCTGGGAGGACTCCAACTACGGTCCTGAGGTGTTGCTGACTGCTCCCGCTACTCGAATCGTGAGCGCAGGGTGGCCGGGAAACAAGCTACGTATCAGCGACGGAACCTCTGATTCGACTGCCTATGTGTCCGCGGCTGCGGCCTTGCTCCGGTCCAAGTTCCCCGACCTTACGGCAGGGCAAATCGCGAATCGTCTGGTGAGGACCGCCGCTCTGCCTGAATCTGCGAAAGGTCTCACCCTCCCTGACGAAAAGTACGGATACGGTGTCATTCGTCCGCTAGCTGCCCTGACAGAAGACATCCCCGTCGGCTCCAAATACGGTCCGCTCAAGGTCCCGGGGGCTGAGGGCTCCTCCGCTGCTCCAGGTACCGGCAAGTCCGACACCGATCACGCCGCGGAGAACAAAGAGGCGGATCAGAAGCAGTTGGTCTTCTTCGTTGTGCTTGGTCTTATCGCTTTGGCCGTGATCGGGCTCATCGTGTTCCTGATCGTCAAGCTGTCCCGGCGCAACAAGAACAAGACAGGTGGGTCTGGTGGCCCGGCCGGCTACCCACAGTATGGCCAGCATCCGGTCTCCCCGCAGCCGCATGCCTACCAGCAGCCCGTTTCGCCGCAGCAGAACCCGTATCAGCAGCAGTCCCCGCCGCCTCACGGCCAGTGGCCGCCGCAGCAGTAGACAAGGACAGCGACACACTCAACTGGTCACCCAGGGTGCAGCGTGGGGCACGGCCTCCCGAGCGGTTCGTGCGTGCCGAGCCCAGCGAGCGTCGGGAGGTCTTGTACCGGTTTCCATGGCGGGTGGGCTGGGCGCGGAAGCCGCAGGCACAGTTCGCGGCGGCGTGGTGGGCCGCCCGGTGCTGGAGGTGGGGTGGTACTGCGAGTGCAGGACCCGACGGTGAGGGGGGTGCTGCGTGTGCCGCAAGTATGGCTCGCCAGAGCGACGGCTAGCTGATGGCTCCCAGAGCTGGCGTCGGTGCGGGTCGAGGCACCGAAAGCGGGGCGGGTCTTCACAGCAGTCGCGGTGCTGCAGGACGCGGCGCCAGCGCGGTTCACAGAGGCGGCATTGCAGGTGCTCCCGACGCACGCACCGGCCGCCCCGAGGACCAAGAGCAGCGCGAAGGCGAGCGCCCCGACTACTTGGTCGAGGACGAGGAGATCTGGCAGCCGCTGCGTAACGTGGCGCCGCGAGTCACCGAGGAGTAGTCCGCGCGGCCATGCCGTGCGTATCCCCGCACCAACCTGAGAGAGGACATACGGATGGGCTTGGACCGGGTACTTCGCGCAGCCGGCTGCGGCGCATTGGCTGGTGTGCTGTTGTTTGCCGCCGCACCGTATGCGACTGCAGACCAGGTCAGAGAAGACCAATGGGCGCTTGAGGCACTCAACGCTGAATCCGTGTGGAAACTCTCCAAGGGAAGTGGCGTCACGGTTGCTGTTATCGACGACGGAGTAAACGCCAGTCATATTGACCTTCAAGGGAACATCCTTGAAGGTAAAGACTTCATGGACGGAGGCAGTGCATCTCCAAACCCGGGTGATAACCACGGCACAGCCATGGCCTCGATCATTGCTGCTCATGGACATGGCGCGAATGACGGTGTTATTGGGCTAGCGCCAGAGGCGAAAATCTTGCCCATCCGGGAATTCGGTACCGATGGGCCAGGGCTTCCTGTTTCCATTCGTTTTGCAGTTGACAACGGTGCATCCGTGATCAACGTATCGCAATGTTTCGGCTCCAACTCCAGTGAAGAAGTGGAGAAAGTATCAGACGCTGTTGCCTATGCGTTGAGCAAGGACGTACTGGTTGTTGGCGGTGCGGGAAACGACGGTAACGCAAGCAAATGTTATCCAGCCGCTTCCCCAGGGGCATTGGGCATTGGTGCTGTAGCGAACGACGGGCAGATCTGGGAAAACTCCAATTCTGGTGCACATGTTTCCTTAACGGCTCCGGGTAAAAACATTGTCGCCGCGAAGGGGACGGGTGACGGATATCGTACTGGCGCCGGTACTTCTGACGCTACTGCTTATGTCTCAGCGGCAGCTGCCCTTCTCCGGTCGCAATTTCCCGACCTGACGGCCGGGCAAATCGCAAACCGTCTCGTGAAGACGGCGGTGCTGCCTGAAGCGGAGAAAGGGCTCTCCCTCCCTGACGAAAGGTACGGCTACGGCATCATCCAGCCACTTGCCGCTCTGCAAGAAGACATCCCGGTCGGCTCGAAGTACGGCCCGCTCGCTGTTCCTGATTCTCTGAAGGCGAAAACTGCCACCCCCGAGATCGGCATGTCCGACGAGGAGCAGGAGAAAGCAGACCGGAAGGCGTTGATCATCTGGTCCGTGATCGGAGTTGTGGGTCTTGCCGTTGTCGGCCTGATCGTATTCCTGATCGTGAGACGGTCCAGGCGGAACCGGGGCAACGGCGGCGGCTACCCGCAATACGGCGGGCAGTCGAACCCGTACGGACAACCTGTTTCGGTGCAGCACAATCCGTATCAGCAGCAGCCCATGCCGCCGCACGGCCAATGGCCGCCTCGGCAGTAGGGAGAGCGTTTTCTGATGCATGTGCACTCGACTGCGGCAATCTGTAGCCGCAGTCGTCACGGAACTGGTCTCCCTCACCGGCACGTCGCGGGGGCGCGGCCGGTTGTTCGTACGGGGTGGGTGCGGGATGTGCGCAGGACGGCCGCAGATGAGGGTGGGGGAGCGGCGCGTTGCGTGAACGCTCCGGTCACGGCTCCCAGAGCGTGTCCAGTCGCAGCCGTACGGCATACAGGCCGTCGGGGCCCCCGACGACGAGTACGCCCCTCGATGTGAGGGCGAGGGCGTGGCAGGTGTGCAGCAGGGGCAGGGCGCGCATCCGGCCGGACGGTACGTGCCACAGATGGAGCTCGGCGTCGCTCCAGGCGACGGCGAGCACCGGGCCGGCGGGGGTGTCGGCCGCGGCGAGCGCGGTGGCCAGGTAGGAGCGCTGCTGCACGGGCACGGGCATCGGCTCGGTGGAGGTCTCCCACAGGCGCACCGAGCCGTCCAGCGCGGCGCTGAAGACGAAGGTCGGTCCGCCGGCGGCGATGCGCAGGCAGGTGGCGGCCCGGACCGGCTGCTCGTGTACGCGGTGCGAGCGCGGGGCGTCCTGGCCGTCGCCCAGGGACCACAGGTGGAGGGAGCCTCCTCGGTCGCCGACCACCGCGTAGGGGCTCCTCGGGTCGCCACCGAGCGCGGTGACCTGGGTTTCCTCCCTGGTGAGGGCGGCAGCGCCATGGTGTTCGGCGATGTGCCGGAGCCCGGCCGCGTCGTCCTCGGGCGCGACCGGCAGCAGGGTGCCGGTCTGGTCGAGCAGCAGCATCGAGTGGGCGTCGCGTGCGGCGACCGAGACCGGTCGTACGTAAGGGGGAGACCCGATCACTCCGGCCGGGGTGCCGGTGTTCATGTGGTGCGTCCGCAGCCGGCCCGTGGCATCGGCTGCCGCAAGCCGGTGCTCCTCGCCCGGTACGGTGGCCAGCGCGGCCACGGGGAGGTCGGGTTGGGCCCATACCGCGGTCCACCGGTGCTGCTGGGCGAGGGGACGCAGGTACTCCGCCAGGACCGGGTCGGTGCCCACGGCGGCGGCATGAAGCAGGGCGGCCCGCTCGACGCCGTCCGTGTGGTGCCCCGTCAGCTCCGGTGCGGCGCGCCGCCACACCCGGCGGAGGCTGCCGGGCGCGGGGACACGTTCGTCGGCGAGCAGGGCGGTGAGCGCGGTGGCCGAACCGTGCACCAGAAACCCGGGGTCCGCCAGCAGACCGCGTACGGCGGCCTCCGAGTCGTCGGCTCGCAGCGCCGCGTCGAGGATGTGGCGGCGGGCCGGGCCGGGCGCCCGGGACCAGTCCGGCCGGCCGTCGGGGGTGAACGGGACCGTCGCCAGAAGCTCCGCGAAGGTTGCCCGCGCGGGGGCCCGGCGGCCGGGAGGCGGCGCGGTGCGGCCGCCGAGATCGATGATCTCGGCACCGTCCGCGGGCAGCAGCCCGAGGTCGCCGGTCTCCACGGCGGCGCGTAGCTGGGGGAGCGACAGCAAGGGGTCCAGCAGGTCGGCGACGAGGGCCGCCGGGTCCGCGGCCGGCAGGTCCGCAGGGCCTGCTCCGGCCCGGTGCGCGTCGGGTACGAGCAGCAGCAGCGGCCGCTGGTCCCGACCGATCCGGTCGAGCAGACGCGCCGGGGGCAGCGGGCCGTAGCCGAGCTGGCGTCCCAGCTCCCAGGCGAAGGTCTCCGCCGTCAGCCCCTCGGCCGGGACGGTGGCGTGGACGGTCGTCCGCGGATGACCGGCCGCCCCGGCCAGGAACCAGGCGAGCAGACGGCTCTTGCCGCTGCCCTCCGCACCCCTCAGCAGGCAGAGCCGGGGCCGGTCCCCGCTGTCGTCGGCGGCCCAGTCGAGCAGTTGCTGCCCGAAGGCCCGCTTGTCGTCGTCGAGCGGCGGCCAGGAGGCGATGTCCGGCGTGGCGGCACCGACGGTCATGGCGTGCTGCTCCCCCTGTTCGTGTCTCCCGACGTCCTACCGCGGCGCCTGGTCCGCCGCCTCGCGTAGCTGCCGTATGCCCTCGGCGCGTGACTCGGCCGTCTCCCCGTAAGGGAAGTTGTGGGTCAGCTGCGCGTCGGGGAGGACCTGCCCGAGCCACATCGCGCAGTAGTGTCCCGGCATGAAGCAGGCTTCCAACTCGGTGTGAATCCGCAGTACTTGCTCCGGCCGGACACCTGCCGCCCGCAGCCGGGCCCACAGCCGCTCCTCCGGGTGGACGGCGATTCCGCCGGCCTGCGTGAGGATCTGCTTCTCGCCCCGGTCGTCGACGATCTCGAACGCGGTGAACCACTCCGCGCTCGCGGTGTCCCTAATGTCGTCCAGGACGAGGGGCCACCAGTTCTCGCGTCCCTCGAACGCCTGGGGGTCGATCGCCCGCAGGCTCCGCTCCAGCTCCGCGTAGGCGGCGGAGGCTTCCTGCGGCGAGTCGGTGCCCAGGATCACGCCGAGGGCCCGGTCGAGCGCGGCGAGCGACTGGGCGAAGGCCTCCGGAGCCGAGTTCACGAACCGCAGTTCCTCGGTCCAGTCGAGGAGTACGGCACGCACCACGCCCTGGTGGTCGCCGCAGATCTCGAAGCCCCGGTCCGAGCCGAGCCGCGCCCACGACCGGCACTCCTCCCGCACGACCGTGCGCCCTACGGACCGGGCGAACTCGTGCAGCGGTACGGGATCGGACTCGGCCGTCACGAAGTACGGGCCGACCTCCAGGGGGACGGCGATCCCCGCGAGCCGCCGCACGCTCTCGGGGGCGCCGGCCGGGTCGGTGGCCTCGGCCGTCGTACCGAAATGCCGAATATCGCCGCCGCTCATCGCTGCCCGCACCCCCTGGGAAGGACTCTCACCGTGCCGGGAAACTACCACATGCCGCCGGCGATATCGGCGACCACGCCTTCCCACCAACCGGGTCCCGCAAAAGGAAGCGGATCGATACCGGAAAGTTCCGCCTGGATCTCGTCGGCGATCCGTTCCGTCTCCTCCACGGGAAGCATCTCGTTCAGACCCTGGGGAGCGTAATCCGCCCGCCTTTTCTCGAGCAGCCACATGCCGTACACCATGGAAGAGAGGTCGGTGTGCATCGGCTGGATCGCGCGCACTTCATCGTTGATGTCATAAACGATGCCGGTTGTGCCGTCGAGAGCGATATCGCTGTAGACGGCCTTGCCGAGGTGGATCCAGTGACCGAAGTCGGCAGGCGCGCCTTCATATTCCGAGAAATCGGCCGCCGGGCGGTGGGAAAGAAGCGGTGTCAGGCCGTCGGCGAGGTCGTCCCTGATCTCGAACAGTACGCCTTCGGCCACGGGAATTCCGATGTCGGCCAGGAAGGCGCGCGATGCGGTGTGGCCGAGGATCGCGCTCTGCCGGTCCAGTGGTGTACGTGCAATCTGCTCTGCCGGGAAGACACCCCGCAGGAGCTCGGCGGTGACCGGAGCGATCATGACCCGTCCCTAGTGCGAGCTGTACGTGACATGGGCAGGCGTCAAGGTAGCACGGCTCTTGTCCGCTGCCGCTGCGCAGTCCTCAGGGGGCGAGGCGGGACAGGGAGCCGACATATTTGGCCATCTCTCTGTTCCCTCTCCTCTGGGATTCCTGCAGTGCCCCTGTCCGATCCTCCTCTTCTTGCCAGGTGGCGAGCTCGCCGTACTCGAAACTGTGCGACATTTTGGTGTTCGGGAAGTATTTCTCCATCCATTCGCCGCAGAAGTACTGGGGGGTCCGGCAGGGAGCCCGTTCGCTGTAGGCGTCGGTGACCAGATCGACCATCCCGCTGTTTTTCAGTGGGACCCCCACGATGCGTTCCGAGTGCGGCCCGTCGACCCGCCCGACCAGGATGAAACTGTTCTCCCCCTCTCCGACCCGGAACGCGGCATAATTCTTTCCGGCGTAGTATCCGTCGGAGTGCCGGGCCAGTTGGGTGGCGCGCGAGAGTTCCGTCGTGCCGGCGGCGACCGGCGTCGAGTTCTTGCGCGGCCCCTCCGTGCTCGCCTTGTCACGGCCGAGCGGAACGGCTTCCCGCCTGCTCTCCGGCATCGGATTTCCGTCGGACAGCAATCTGATCAGAGCGCTGTCCTTTTTCGGGTCGAGTGTGGCGGGATCCACCTCGACCTTTTTCCCGTCGGCCTGGAGAAGGCTGACCTTTCCCGATTTGTTGAGGAGGTAGACGGGGGTCTTGTCGCCGTATTTCGCGAGGTCGCCGAGGGAGTGGGCCCTGTGCAGGCCCTCCAGATCCCGAGCCGTTCGGCCATCGCTGTCGCGATAGTTTCGGCTCATCGTTTTCATGCCGCGCGTCATGTTGTCGTCGAGGTGCTTCGCGGCGGTCTTGGCGGCCTCCTCGATGCCGTCCAGCACGGTCTCGATGACGGGGTTCGCGGCATTCCCGATGGGGTCCCTGCCCTTGGTCCGGCCGTGCGCCGACTTGGCCCGGGAGAGCTTGCCGCCCGCCTTGTCGCGGACCTTGCCGCCGGCGTCCTTCAGCCCGGAGTCGGCCCGGTCGAAGGAGTCGGGGTCGTGGCTGAACTGCCCGCTGTCCACCCCGTCTCCGCCGCTGCTGTTGAGGCGCATGGAGGACTGAGCAGCGTCGACGCCCTGGGTGAGGCCCGCCCGGCCGGCCTGGGCGGTCCGGCCAAGGTCGACGCCGTCCTGGACCCCCAGGGCGTTGCCGCCGAGCTGCACGACCAGGTCACCCGTCATCGAGCCGAGGGCCTGGTAGACCGGGCCCATCGCCACGTTCACGACTTCCTCCGCGACCCGCTCGCAGACCTCCTGGAAGATCTTCTTGACCGCGATCCGGGTGGCCTGGGTCGCCGCGAGTCCGCCGAGTGCCGACAGGCCCAGCGTGACGGGTGACGCGGCTACCGCCGCCGCTATCTCCGCGGCCAGGATGCCGAGTTGCGCGATGGCCGCGAGCTTCGCCCCCTCGATCAGCACGGCGACCCCGTCCAGCGCGGTGGCCGCCATCCGGCCTGCCTCGGCGAGGTTCTGCAGGTGGGTGTCCTTGACCTTGCCCCAGTGCTTCTCGAGCGCCTGTATCGCCAGGCCCTCGTTCGCCCCGATCAGCTCGGTGACCGCCTTGTGGGCCTCCGCCGCTCCGTCGTCGATGTCGTCGGCGAACTCGCGCATGGCCTGGGCCATCTCGCGGTAGTCGTCCTCGTCGATGTTCGGCCAACTGACGCCGATCAGGTCAAGGGCCTCGTCCAGATAACTCGGTAGGGTGACACCCACAAGAACCCCCGTTCGAGAGTGACTTGAGAAAACGTAACTTCGAACGGTTCGGAGATACAAGGCTCCTTGCGGCGCTCCGGAGTCGTCCGGTGGAGGGTGGCGCCGGAGACTCCCGGCCCGGGAGCTGTACCCGGCCCACCGGGCTTCCGGGAGTCACGCCCGGCCCGCCTGGCTCCCGCAGTACGCGCGGCCCAACGGGCTCCCGGAAGCGGCCCCGCCGCCCGTGCGGCCCGGGCCCGGTGCCGGCCAAGCGCGGACGGTGGAACCGGGCGCCCGGAGGCGGACGCCCCGGCGAGTCGGCGCTCGTCTCAAGATCACCTGTCTGCCTCGTGGCTTGATAGGGTCACGCCAAGCAGTGACCGCGTGACAGTGCGGGCGCAGGAGATACGGGGGCCATGTGTCGACCTATTCGGTTGACTCGAGCGGGTATCAGCAGAACGTCCGGCACCTGGACGCCGCCGCCGAGGACGTCGGCACGGCCGCGTCGCAGATGCCCGGCGAGCAGTGTTCCGTCTACGACGTCTACGGCGGCGAGGACTCGGGCCCGGCCTTCGAGCGGTGCGTGACCGCCTGGCACGACGAGGCGGACGTACTGCGCTCCGCCCTCGATGAGATCGCGAACAAACTGCGGGTGACCAGCAACAACTACGGTCTCGCGGAGGACTACGCCGCCGGGCGGGTCCACGGGGCCGCGACGGTGACCGGAGGTCCGGCCCCGGCGCCGGCCGCCCACGCGTCCGACCCGTCACCGTTCGGCTGAGACGCGAGGTTCCTTCCGATGAGCACCGAAGAGCAGATCCTGCACCTCCATCTGCCCACCCTCCTGCGCCACGGCATCGGGGCCGGCGCCGCTCAGCGTCCCGCCCTCTTCGGTGAGGGCGCCGTCGCCGCGGCCGTCACCCTCGACCGGCTGGGGGTCCAGCCGCGGGCGGTGGCGTTTCTGGCCAAGACCGTACGCAGTGGCGGTGTCCGGTACGCGGCCGGTCTGGAGGAGCCGTTCCCGGGCGAGGAGGCGTCCCGTACCGCCCGGGAGTGGCTGACGGGCGCCGCCTCCGTCGCCGCGGACACGGACGACGACGAAACCGTCGCGCGCTGGTTCGAGGCCGTCGCCGAGATCCTCGCCCTGCGGCACCGCACGTCCGCCGCGCGGCGCTAGAGACGTACGTCCGCCGCGCGGCGCGAGAGGCACGCCCGCCGCGCGGCACGGAGACACCGGGCGCGGACGGCGGGCGGCCGCGTCACCTCTCCATCTGCACCACCTCCACAAGGACACGGAAGGGAACCCGGACATGGCGGGGGAGTCCACGACGTCCCGGCGTTCCGAGCTGGCCGGTCTCAAGGGCAGCATCCAGGGCGCCGACGACAAGAACGGCCTCATCGAGGCGATCAGGAAGTCGCTGGCCGTGAAGGCGCCGGTCGGCGACCCCGGCGCGATCGAGGCGGCGTCCCGGCAGTTCAAGCAGGCCGTCAGCACGGTCGACGAAGCGGCGGGACGCATCGGGAAGGCGGCCTCCGGGCTGCCCGCGGTGTGGACCGGGACGACCCAGGTCGCCGCCTCGGAGGTGGTCGCCGCCGCGCGCCGGGCCGCCGATCAGATGCGCGAGGCGTTCGAAGGGAGCGCCAAGGCGCTCACCGCGCTGGCGGACGGCGTCGAGGACGCCCAGCAGCGTGACCGGGTGGGGTGCGAGGTGCTCCGCGAGGCCCTGAGCTCGCTGGGCGGTGCGGACGGCTTCTTCGACGGCATGTGGGACAGCGACGAGGAGGACGTCGCCGTACAGCGGGCCAGGACGCAGGCCACCGACGGCGTCGAGCGGCGCCACCAGGCGGCGGTGATAGCCGACGACGCCGCGCGCAAGGCGGCCGGCGAGCTCAACCGGTGGGCCTCGGAGGCCCGTTCCGGAAAGCTGGAGGCGAAGGGGCTCACGGCGGCGGACAAGCTGATGCTGGCCGACACGAGCAGCGTGAGCGAGTCCGGCCCCGACCGTGAGTACAACGAGATCCTCAGCGCGAACGACCTCGAGCGCTCCGCCGCGTACATGGACAAGATGAGCCCCGCGGACCGCGCCGAGCTGGAACGGATGCTCAAGGACTCCAAGTCGCCCGAGGAACGGGCGTACCTGATGAAGACCGTCGCCGCCGGCTACGACATGGACGAGGTCCGGGAGTTCCGCCGGAAGATCCATCCGCACGGCGACGACGAGGCATGGCTGCGGCGGCACCTGTCGCCCGCGGTCACCGAGGCCGACAGCAAGAACCGGCCCGGTGCCTGGGACGACCTCACGTACAACGGGCAGAACTGGTCCCAGAAGGGCAACACCTGCGTGCCCGGCTCCACGATCGGCGCGCGTGCCATGGTCGACCCCGTCTACGCCCTGGAACTCACCGGCGGACCCTCCGGCCAGGAGGACGACGGCGCCGCCTTCCGCGGGCGGCTCGACGACGAGCTGATGCGGGTCCACGAGGAGGGCGACGGCAGCTACGACTCGGGCTTCTGGTGGGGAGCGCCGGACGGCATGGACAGCGACGGCCAGAACGAGGTCGCCAACGCCGAGATCAGCCCCCACACCGGCGCCGAGTACGAGTACCGCGAGATCCGTGAGGGCGCGGACGCCCGGCGCGACGTCCTGCCCGACATCGAGAGGGCGGTCGCGGAGGGGAAGCCGGTGCCCATCGAGGTGGAGGGCAAGGACGCCAACGGCGACCGGGTCGGCCACCAGATGATGATCATCGGCCAGGAGGGCGACATGCTCCAGGTGTACAACCCGTGGGGGCACACCACCTGGGTCAGCGAGGACGACTTCGTCAACGGCCACATGGACAAGGCGTCCGACGAGCGGTTGCCCAACGCCTTCGCCGTCCATGTCCCGAAGTGACCGAGGAAGGCACCCGATGACCAGCAAGGTCCTCTCCCGGCGGGGTCACGCCCGTCTCGTCCCGTCCCTGCTCGCGCTCGGCGCGGCCGGCGCGCTGGCGGCCTGCGGAGCGGCCGCCGGACCGAAGGAGTACGGGACCGACCGGCGCACCATCGAAGCCGAGGTCGGAGAGGAGTTCGCCCTGTCCCTCCCCATGCATCCGTCCCAGGGGGAGTGGTGGTACCGCGTCACTCCGCACCCCGACGCCGAGGTCGTCCGCAGCGAGGGCGACCGCGAGGACTACGAGGGATCGGACCTCGTGGGCGGCGGTGACGGCACCCAGTACTTCGATTTCAAGGCGGTGGGGCCGGGAACCACCGAGATCCGCGTCCTGCACTGCCCGGTGGGCACCTGCGTCGGCAAGGGCGAGTCGGCGTCCCCCAGGCCCGACGCGACGTCCACCGACTCCGACCAGGCCAACAAGGCCCGCTACTACACCTTCACCGTCTCCGTACGGCGCTGA

Protein sequences of DBSCAN-SWA_2

>NZ_CP010849|5706444:5756901|5709192_5710041_+|WP_044388450.1|DBSCAN-SWA
MLTQTTSRVLEPADLDAALAVLDREPVANAFVTSRVQVAGLDPWRLGGEMWGWYEDGILTSLCYAGANLVPLCATPRAVRAFAGRARRAGRRCSSIVGPARPTAELWRLLEPGWGPAREVRPHQPLMITDRMPAGVAPDPYVRRVRKDEMETIMPACVAMFTEEVGVSPLAGDGGLLYQARVAELVGSGRSFARFDADGKVVFKAEIGAVTDRACQIQGVWVAPEYRGRGLAAPGMAAVLRYALTEVAPVVSLYVNDFNTPARRTYRKVGFQEAGAFMSVLF
>NZ_CP010849|5706444:5756901|5712606_5713509_-|WP_044384483.1|DBSCAN-SWA
MAFEPPRRLVRALGETAPDGDGWLERLPELARRAVALRELTVERVQVPGGRSSLVVLVRRADGSPAVLKLAPPRARPESERVALAHWGGRGAVQVLDEADPTEGVLLLERLHPDVSVRSLPEAKALLEAAGTLRRLWVEPPAGHRFETVAERTGRQAEAMRSGAAADPEVAPLVEAALAIREELLVRPPEGVLLHGTFRQSKVLAGDRMPWLAVGPDPVVGESAFDLARLVRDRVEDLIAQPSGAATTRRRIKRLAESLEVDQERLRGWTLFRAVESGVRARRVGREKDAELLLEFAGWL
>NZ_CP010849|5706444:5756901|5741940_5743179_+|WP_107071224.1|protease|DBSCAN-SWA
MAVLACGLPFAGAAPAAAAERVRTTLADGDVRFQIDDTSCSFPSDPIKGTPWSLQRVVLDQLWQDTKGKGVKVAVIDTGVDAVNPQLRPAVVNGKDFLSKGGNGKTDEVGHGTKVAGIIAARKSDESGFIGIAPEATIIPIRQNDDQGTGNVGTMIQAIKYAADAGAEVINISQDTASKMDPTVHAAFQAVIRYAQEKDAVIVAAAGNNGADGKIKETYPAAYPGVLAVAASDRNNARAPFSQSGRFVGVAAPGIDMISTVPVGGHCVDQGTSFAAPYVSGVAALIRAKHPDWTYKQVITQIEQTADRTKPGRDDFVGWGVVDPAAAVNEDTTEPSEKGPTPDPIGLAGDSADVQAATLVLGESRQERMERYALYVLATGAAVVLLLFGGGRVLSDWRRKQGVGSNVESTGS
>NZ_CP010849|5706444:5756901|5721044_5721950_+|WP_044384498.1|tRNA|DBSCAN-SWA
MTAKHTPPDGLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLDPMATGVLVLGVEKATKLLGHLALTEKEYLGTVRLGQTTITDDAEGEITASTDASKVRREDIDAGVAKLTGDIMQVPSKVSAIKIDGVRSYKRAREGEEFDIPARPVTVSSFAVHDVRDAVAEDGTPVLDLVVSVVCSSGTYIRALARDLGADLGVGGHLTALRRTRVGPYKLDAARTLDQLQQELTMLPLAEAADAAFPRWDVDDRRARLLVNGVRLEMPDAYAGAGAVAVFGPEGRFLALVEHQRGKAKSLAVFG
>NZ_CP010849|5706444:5756901|5714932_5715442_+|WP_029380840.1|DBSCAN-SWA
MSTTQSERLRELLEPLVTSQGLDLEEIAVDSVGRKRVLRVVVDSDTGADLDRIADVSRALSAKLDETDAMGEGEYTLEVGTPGAERLLTEHRHYVRATGRLVKFQLTEGGELVARILTVDGDGVDVEVPGVKGRKPTARRLAFGDIARARVQVEFNRKDDTSHKKEEEA
>NZ_CP010849|5706444:5756901|5739284_5740850_+|WP_044384523.1|DBSCAN-SWA
MATRRDELNAYSFARRRTVAAFLQPSPHGSEEAAPRPFKTVLPSLGLATLVVIGFGAWGMLSPTAPKGWDEEGKNILVGSESTTRYVLVRTKGEEKPSLHPVLNLASAKLLLKGESPKVIKIKESVLDESKYPMGATVGIPFAPDRLPSSKDAETVKIWALCEAPGKGQDNQPVRATYVLDQSDYDTLLHKGDKELNQHEALYIEAPAAPGGTGPRYMVTADGRAYLMGGKDWKLRSESALKTLERAVFGDGVTPQKVSAEFIKTLNVVGAVDFPNLGSGVGAPAQVVGLDPSLSKVGLVLEAPSGLGKQKYIVLKDRVQPVSDFTAQLWLRSPWVEGVYGGKNPEPVEVTFNDIQPADGEWLSEMNWPKEPVAQANTHWEAGGNKVSCSIWHGKKDQYTGLPQMTVWSGREYPKDVSQSGSSTYVSPGSGLLFKRLTGTSAGGGNVYLVTDTGLRYSVPARNDSQVTGGEKADGQQQTNTAQVRLGYDKIRPVSVPAAWADLLAAGPELSSGNAQQAQGS
>NZ_CP010849|5706444:5756901|5729119_5730031_-|WP_044384509.1|DBSCAN-SWA
MTTETTTTSPRALARRRRRASAARFWRQYRTHRAGLFGLAALVLFALLALTAPLLVGSGVSNVTDAPGRPLQGPSAAFPLGTDQFGRDLLGLLVWGARVSLLVGLLAAVLSVAIGTLIGVTAGHFGGWYATVMMRITDWFLVMPTLVLAIALATVMSRSLTTIVVAIGVTTWPTTARLVRAQTLAVETRPYIERAKALGGGHRHIMTRHVLPNVMPLVLAQTTLIISSAILAEATLAFLGLGDPTVVSWGGLLQDAREAGAVSAGHWWYLVPPGVAIALVALAFTLCGRAVESVLNPRLGVGR
>NZ_CP010849|5706444:5756901|5706444_5707749_+|WP_044384475.1|protease|DBSCAN-SWA
MTTLMFILGIVVFAVGLLVSIAWHELGHLSTAKMFGIRVPQYMVGFGPTLWSRKKGETEYGVKAIPFGGYIRMIGMFPPGADGRLEARSTSPWRGMIEDARSAAFEELKPGDETRLFYTRAPWKRVVVMFAGPFMNLILAVALFFTVLMGFGITQQTTTVASVSQCVIAQTENRDDCKKTDPASPAAAAGLEPRDRIVSFDGVRTDTWDELSDLIRANPGEEVAIVVERDGREVTLHAEIATNKVAKKDAAGQIVEGEYVTAGFLGFSSATGVVKQDFGESVTWMGDRIAEAADSLAALPGKIPALWDAAFGDGPREPDSPMGVVGAARVGGEIATLDIPPTQQLTMFIMLVAGFNLSLFLFNMLPLLPLDGGHIAGALWESLRRHTARLLRRPDPGPFDVAKLMPVAYVVAGIFVCFTILVLIADVVNPVRIS
>NZ_CP010849|5706444:5756901|5750283_5751117_-|WP_044384542.1|DBSCAN-SWA
MSGGDIRHFGTTAEATDPAGAPESVRRLAGIAVPLEVGPYFVTAESDPVPLHEFARSVGRTVVREECRSWARLGSDRGFEICGDHQGVVRAVLLDWTEELRFVNSAPEAFAQSLAALDRALGVILGTDSPQEASAAYAELERSLRAIDPQAFEGRENWWPLVLDDIRDTASAEWFTAFEIVDDRGEKQILTQAGGIAVHPEERLWARLRAAGVRPEQVLRIHTELEACFMPGHYCAMWLGQVLPDAQLTHNFPYGETAESRAEGIRQLREAADQAPR
>NZ_CP010849|5706444:5756901|5741459_5741753_+|WP_044384527.1|DBSCAN-SWA
MSGQILVNFQTISQAAQDVRSTANNIRRQLDELEAGVAKIATSWEGQAQEAYRAKQAEWDQRANSMQQTLEAIAKALDGAAQNYQATEQKNASIWGG
>NZ_CP010849|5706444:5756901|5753923_5754286_+|WP_044384546.1|DBSCAN-SWA
MSTYSVDSSGYQQNVRHLDAAAEDVGTAASQMPGEQCSVYDVYGGEDSGPAFERCVTAWHDEADVLRSALDEIANKLRVTSNNYGLAEDYAAGRVHGAATVTGGPAPAPAAHASDPSPFG
>NZ_CP010849|5706444:5756901|5720601_5721048_+|WP_029386803.1|DBSCAN-SWA
MADNARAKRLADLIREVVAQKLQRGIKDPRLGSHVTITDTRVTGDLREATVFYTVYGDDEERQAAAAGLESAKGILRSEVGRAAGVKFTPTLTFVMDALPDTARTIEDLLDKARQSDEKVREASAGASYAGGADPYKKPADETDDTAE
>NZ_CP010849|5706444:5756901|5714075_5714603_-|WP_044384487.1|DBSCAN-SWA
MPPFTSSPRTRPGPRRRSLLASAAGAALLAGCSAGPGSDGTGGSPSAAARVRARAARDSERLAARYDAVIAAHPGLAARLRPLREEVVRHAEAFGGGTAPAPRTSPAQASPAVSPPAAVPGNEKDALAGLAAAERELTARRTGALADVPGELARLLASVAAAGAAHVYLLTEDHG
>NZ_CP010849|5706444:5756901|5754815_5756399_+|WP_044384550.1|DBSCAN-SWA
MAGESTTSRRSELAGLKGSIQGADDKNGLIEAIRKSLAVKAPVGDPGAIEAASRQFKQAVSTVDEAAGRIGKAASGLPAVWTGTTQVAASEVVAAARRAADQMREAFEGSAKALTALADGVEDAQQRDRVGCEVLREALSSLGGADGFFDGMWDSDEEDVAVQRARTQATDGVERRHQAAVIADDAARKAAGELNRWASEARSGKLEAKGLTAADKLMLADTSSVSESGPDREYNEILSANDLERSAAYMDKMSPADRAELERMLKDSKSPEERAYLMKTVAAGYDMDEVREFRRKIHPHGDDEAWLRRHLSPAVTEADSKNRPGAWDDLTYNGQNWSQKGNTCVPGSTIGARAMVDPVYALELTGGPSGQEDDGAAFRGRLDDELMRVHEEGDGSYDSGFWWGAPDGMDSDGQNEVANAEISPHTGAEYEYREIREGADARRDVLPDIERAVAEGKPVPIEVEGKDANGDRVGHQMMIIGQEGDMLQVYNPWGHTTWVSEDDFVNGHMDKASDERLPNAFAVHVPK
>NZ_CP010849|5706444:5756901|5710094_5710625_+|WP_044384479.1|DBSCAN-SWA
MDLAIGPLDLPAHVDEALAVQAAAFGLGPDEVAVRRQIVLRHMTYPGARALGATVGGDLVGFVYGMPNDRTHWWSTVVEPYLRAQDHEEWLDDSFVITELHVHPHHQNRGIGRALITAITDGAAEPRSILSAIDTESPARALYRSLGYRDLARQVVFPSAAKPYAVMGAPLPLRRR
>NZ_CP010849|5706444:5756901|5737757_5739089_-|WP_078969319.1|DBSCAN-SWA
MSTATRSRRRNGSRRTQENQGQPEPAQRSANPARVSPAAPSLARRPGSIGPIRVQQLVGFELAAAVVLIGWLLRPIGLTIGIVLAVPLVLAGLLRRRGRPLPEWFTTARALRDRRKRNAEPVPPGTDPGFAPAVECDPALRTYAFHDREQREVGMVGDGTFLTALVQVQAADIPLRPAHGSRDIPLDLIQGLLEVDDIRLASVQVVQHTQPAPAPHLPPQAMAVRSYGPLQAQSMTPGLRLTWVALKLDPELCPEAVAARGGGMQGARRALLRVADQLASRLMGAGLQAKVLSESEVVAAIATSSCVNPLATTGGAALDGSRSTRRTAETSRAWRCDDRWHTTYWISRWPQLGGGAPALPQLVGALTSSPALASTFSLTISKRRGRVLALSGHVRLTGRGENGLDEAVQHLERAASAFKIGLVRLDREQLPGVLATLPLGGTR
>NZ_CP010849|5706444:5756901|5728121_5729123_-|WP_044384507.1|DBSCAN-SWA
MSLLDVRDLTVTYAGGAAAVRGVGLRLEAGRKLGIAGESGCGKSTLALALLRLLPPGTRVTGEILLDGEDVLTMKWGRVRAVRWAGASIVFQGAMHSLNAVHRVGDQIAEPILLHGKATPAGARRKTGELLEQVGLPAARAGAYPHELSGGQRQRVMIAMALACDPRLIVADEPTTALDVMVQAQILRLIEQLVAEQDLGLIMISHDLAVLADTCDRLAVMYAGRVVEEGPARQVYEDARHPYAQALSAAFPRIGDPASRFAPRGLAGDPPDPAAVPPGCAFHPRCPVALESCATQDQVLRDAGAHRRAACVRVAGEPAPEPDDFEEARRAAP
>NZ_CP010849|5706444:5756901|5715444_5716431_+|WP_044384489.1|DBSCAN-SWA
MDIDMSALRGLVREKEISFDLLVEAIESALLIAYHRTEGSRRHARVELNRETGHVTVWAKEDPEDLEEGQEPREFDDTPSGFGRIAATTAKQVILQRLRDAEDDATLGEYAGREGDIVTGVVQQGRDPKNVLVDIGKLEAILPVQEQVPGETYPHGMRLRSYVVRVAKGVRGPSVTLSRTHPNLVKKLFALEVPEIADGSVEIAAIAREAGHRTKIAVRSTRSGLNAKGACIGPMGGRVRNVMGELNGEKIDIVDWSDDPAEMVAHALSPARVSKVEIVDMASRSARVTVPDYQLSLAIGKEGQNARLAARLTGWRIDIRPDTEQQAE
>NZ_CP010849|5706444:5756901|5731111_5732959_-|WP_044384511.1|DBSCAN-SWA
MDTQTRSLPGRVRLLAGAGAAALTLTASLATPLNPSPAQARAAGDGEKVLTVAVAQSVDSLSPFLAVRLLSTSIQRLMYEFLTNYDPEDARAVPGLATKWESSPDKLTWTYTIRSGSTWSDGKRVTAEDAAWTFNKMMTDQGAATANGSFVGNFRKVTAASPTKLVIELKKPQATMTALDVPIVPKHVWEKVGDFSKFNNDSSFPVVGNGPFVLTDYKADSYVRLKANKTFWRGAPKFDELVFRYYKDQDAAVSALRKGEVSFVAGSPSLTPAQAASLEGERNIRVNDAPGRRFYALATNPGARAKNGRTFGDGHPSLLDQQVRHALFMAVDREAIIDKVFRGHAVEGEGYIPPRFSQYFWKPSASRKLAYDPAKAARLLDQAGYRLDGDGRRVGKDGEPITYRVLCHATDPNDKAVGKYLQEWWGKLGIGVRLDCLDNVTDPWLAGKYDLAFDGWSVNPDPDFVLSIHTCAALPATPKDTGATDNFICDKRYDELYARQLAEYDPAARADLVKQMQARLYDLGYMNVMAYPNAVEAYRTDQIESITTMPAKAGNIYGQDGYWSWWSAVPAESGDSSGGSSSTGVVLGVAGGFVVLAALGGFAAMRRRATAEDRE
>NZ_CP010849|5706444:5756901|5756415_5756901_+|WP_052808676.1|protease|DBSCAN-SWA
MTSKVLSRRGHARLVPSLLALGAAGALAACGAAAGPKEYGTDRRTIEAEVGEEFALSLPMHPSQGEWWYRVTPHPDAEVVRSEGDREDYEGSDLVGGGDGTQYFDFKAVGPGTTEIRVLHCPVGTCVGKGESASPRPDATSTDSDQANKARYYTFTVSVRR
>NZ_CP010849|5706444:5756901|5751161_5751743_-|WP_044384544.1|DBSCAN-SWA
MIAPVTAELLRGVFPAEQIARTPLDRQSAILGHTASRAFLADIGIPVAEGVLFEIRDDLADGLTPLLSHRPAADFSEYEGAPADFGHWIHLGKAVYSDIALDGTTGIVYDINDEVRAIQPMHTDLSSMVYGMWLLEKRRADYAPQGLNEMLPVEETERIADEIQAELSGIDPLPFAGPGWWEGVVADIAGGMW
>NZ_CP010849|5706444:5756901|5727045_5728125_-|WP_044384505.1|DBSCAN-SWA
MTTSPAAPGAPGGTETAALLSARGLRVAFPGRHGAPRARAVDGVDLDIRPGEIVALVGESGCGKTTLARCLLGLVEPTGGQVTFEGRPLEYSARSLRSYRKRVQLVLQDPSGSLNPRHTVYDAVAEGLRIHGYGGDERAAVAGALARAGLRPPERFFLRYPHELSGGQRQRVVIAGALVLEPELLVADEPVASLDASVRGEILALLLRLRTELGLSALVVTHDLGLAWNIADRVAVMYLGRIVETGAVEQVLTAPRHPYTQALLSVLPEAPGDPVVLTGEPPDPSRVPAGCRFHVRCPVLASGAAERAGVAGACRDRDPEILDGSGTAQVACHWARAGSGRAPSSGPGRTGPAGPDERS
>NZ_CP010849|5706444:5756901|5736372_5736690_-|WP_044384514.1|DBSCAN-SWA
MADVQESTAGTQDEDVRARKERERDELYALDISDVEWHSAPGTEEHEERVEIAYLPGGAVAMRSSLDPDTVLRYTEAEWRAFVLGARDGEFDLEPAPHNGGLAAK
>NZ_CP010849|5706444:5756901|5720252_5720546_+|WP_029386804.1|DBSCAN-SWA
MYVGTLSFDLLLGDVHSLKEKRSVVRPIVAELQRKYAVSVAEVDHLDLYRRAGIGLAAVSADAGHLSDVLDRCERLVAGRPEVELLSVRRRFHGDDD
>NZ_CP010849|5706444:5756901|5736930_5737758_-|WP_044384517.1|DBSCAN-SWA
MSAPTAPATGRPGFGSSTPGFPGQRPGHLPRNPEPSRHGPQRRMRAAFGLLGPRRERHLVDADVLSQLTLPMGDDGLVLGIDPDNQPAVLGLCRPTRLDVVLVGGTWIAQVIALRAAAIGARVAVETARPQLWSPMAQAAGGGQQCVTVHQVGRIAPQGPSPASPVLIIRDLGIRPPRSRLTTAPWQSVLTLLPYLGPTAPRLLSTADVVGVQRISPQEADIVGKVMRLGRDDIVSLPSLSDNVALWCTQKHRQYVMTQPTDAETGLLGAPRRMD
>NZ_CP010849|5706444:5756901|5707934_5709092_+|WP_044384477.1|DBSCAN-SWA
MTAISLGMPSVPTKLAERRKSRQIQVGSVAVGGDAPVSVQSMTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALPVIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNIKKFDDQVREIARAAKDHGTPIRIGVNAGSLDKRLLQKYGKATPEALVESALWEASLFEEHDFRDIKISVKHNDPVVMIEAYRQLAEACDYPLHLGVTEAGPAFQGTIKSAVAFGALLSQGIGDTIRVSLSAPPVEEVKVGLQILQSLGLRQRGLEIVSCPSCGRAQVDVYKLAEEVTAGLTGMDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIEEAMKLAEQMEKDGVASGEPSVSVAG
>NZ_CP010849|5706444:5756901|5710746_5712447_+|WP_044384481.1|tRNA|DBSCAN-SWA
MANAPVQRMSQLLAKTLRDDPADAEVLSHKLLVRAGYVRRTAAGIWTWLPLGRKVLANVERIVREEMDAIGAQEVLLPAILPREPYEATGRWDEYGPELFRLKDRKGGDYLLGPTHEEIFTLLVKDQASSYKDLPVILYQIQNKYRDEARPRAGILRGREFLMKDSYSFDVADEGLAESYALHRQAYQRIFERLGLDYRICAATAGAMGGSKSEEFLAPADAGEDTFADCPHCDFAANTEAITYELKPVDAAEVPAAEDIPTPDTPTIETLAAALGVPASATLKNLLVKVDGEIVAVGVPGDREVDMDKVEAHFAPAAVEMVTEVDFAARPDLVRGYVGPQGLEKVRYIADPRVAPGTAWITGANKPGTHTRNVVAGRDFEVDEYVDVVVVQEGDPCPKCGTGLKLDRAIEIGHIFQLGRKYADALKLDVLGQNGKPVRVTMGSYGIGVSRAVAALAEQHADDKGLVWPKEVAPADVHVVAAGKALQTEVALDVSGKLAAAGLRVLVDDRAGVSPGVKFTDAELIGVPAILVAGRRAGEGVVELKDRRTGEREELPVEEAIARLTA
>NZ_CP010849|5706444:5756901|5741073_5741394_+|WP_044384525.1|DBSCAN-SWA
MAGQQFTMTEEEMIAFSGRISSVNSSIQSEIRRLQTVIDTITGGWKGSAATAYNNLQSQVNQDANKINQILNDIKEAIDQSTKAYAASEEEQRASIQSIAAQSPFG
>NZ_CP010849|5706444:5756901|5743181_5743496_+|WP_044384531.1|DBSCAN-SWA
MAEQYKVDLSEIEGTITRLNRVLKDMGTSASNCKNTTYLPAGALGKNFREAEALYSAHEQMKERLYEIVAHLESVLDDFGQKTKRTHDAFADAEAQNYAAFNRK
>NZ_CP010849|5706444:5756901|5722208_5725946_+|WP_044384500.1|protease|DBSCAN-SWA
MASRNRSRDARGIRAADREPEAHAPDDVLVRIHDPGGRLLGTGFVADHHGTVITSHEAVHGLTRLMVRTARGGVREVSADEVMPLPHRDLALVRTKGLGVPPLPVTVRERIEPGTYVRIAAGGWREARILGTTEVTYAAADRRRPLGPALELAVGTAGRDALAPGGGAAGGPVVDAATGAVVGVLGTALRAGRREAGFAVPLLARTPGDTAAGHRADGPLADLLAENAATVPAHGADLNPAGVVELTATSVGQDSPPGPLGAGAPAAEPVARAAVLRELTAFLDGPAPVLGLVGAPGSGRTTALAALAARRAPNAAPVPALWLRGADLRETDASVADAARRALARAARIVGASERPFPGGPQDATPERLARVARAAGCPLLLLLDGPEEMPPLPAPRLSEWAEGTARWLRETGARLVVACGVEYWERAGAEFGRGTLYGGRGGAEPEGGIGGVPAPTSGAGAGGGGRPDADGGDGGGGERSSAAGGEGPPETVDAGGQRRPPAVAGGARAAHEGGARAVTAALPPWVALRALPPCVPLGDLTEEEARQARARYGVPEDALPEADARHPLTLRLLSEVCAALPGAPDPARVDRDEVFAAYLDLVCLRIAVRLAAHNGLRGTAVRRLAARVAGQVHEAARRSLAAGQGALDRTGFEAVFPWGQAPARLGGGTGWATAVLAEGLLVPAGNGYRFAHEELADWLQGIHLDLDEALGALVHTGARPVPVPHHRIGPVVQAMLHLARHPGSRHLAARLGELVHALEADPHSWWAARLLGEVLPRVPDASPYTEVLRLLADRIAAWRGAGRPVPRELGPDFWTALALPREICADLLRRLILADGPPHRPGPRYLDTAARLLDDDPATVQPLLVRWFDDERPLPGAPHATVATAAQALLHTRRRLAPDALVEVLADSTHRRSGELLTVLAEEEPSAVCRAVGRWAHDARPARRMAAVTYGLRAAPYVHSAADRDLLRQAALRLLGDPGEAAPHGGALALLVQDPAVRGRYLDPALRLFAAGDPCLPPRAMAAALPTHPEPVLNAFRARLAGPDAGEALRRLADAARPGLVGRIAAVIGEAVTERPGILRHLAAYVAQRLDREETGQATAARAALPPLVTALLDSGSEPVRAALATVLGGAGTSASRPLRGELLEFLLARERDPAVLDALLRAAARRDGDDLRGLLHRTAFLLVRTPDGAARFDRALVDLGRHVPGFAARVTGWLAEVPGEWAVLVGPGTRRTLEDLADAPLPA
>NZ_CP010849|5706444:5756901|5751825_5753526_-|WP_063856826.1|DBSCAN-SWA
MGVTLPSYLDEALDLIGVSWPNIDEDDYREMAQAMREFADDIDDGAAEAHKAVTELIGANEGLAIQALEKHWGKVKDTHLQNLAEAGRMAATALDGVAVLIEGAKLAAIAQLGILAAEIAAAVAASPVTLGLSALGGLAATQATRIAVKKIFQEVCERVAEEVVNVAMGPVYQALGSMTGDLVVQLGGNALGVQDGVDLGRTAQAGRAGLTQGVDAAQSSMRLNSSGGDGVDSGQFSHDPDSFDRADSGLKDAGGKVRDKAGGKLSRAKSAHGRTKGRDPIGNAANPVIETVLDGIEEAAKTAAKHLDDNMTRGMKTMSRNYRDSDGRTARDLEGLHRAHSLGDLAKYGDKTPVYLLNKSGKVSLLQADGKKVEVDPATLDPKKDSALIRLLSDGNPMPESRREAVPLGRDKASTEGPRKNSTPVAAGTTELSRATQLARHSDGYYAGKNYAAFRVGEGENSFILVGRVDGPHSERIVGVPLKNSGMVDLVTDAYSERAPCRTPQYFCGEWMEKYFPNTKMSHSFEYGELATWQEEEDRTGALQESQRRGNREMAKYVGSLSRLAP
>NZ_CP010849|5706444:5756901|5717025_5720061_+|WP_078969318.1|DBSCAN-SWA
MAKVRVYELAKEFGVESKVVMAKLQELGEFVRSASSTIEAPVVRKLTDAFQQGGNGKSAAKPAAPKKAAPKPAAPAPAQAARPAAPRPATPKPAAAQQPAAPSAPAPATPGPRPTPGPKPAPRPAPAAPEFTAPPSAPAPAAPKPAGARPGAPKPGGARPGAGQGQQGGQGRPGGQGGGRPGASAPRPGARPAGPRPGNNPFTSGGNAGMARPQSPRPQAPRPAAPGGAAGPRPQGPGGAQGGGPRPQAPGGSRPTPGSMPRPQGGPRPAGPGGPRPNPGMMPQRPAAGPRPGGGPGGRGPGGAGRPGGAGRPGGGGGFAGRPGGGGGAGRPGGGGGFAGRPGGGGGFGGGGGGRPGFGGRPGGPGGRGGTQGAFGRPGGPARRGRKSKRQRRQEYEAMQAPSVGGVMLPRGNGETIRLSRGASLTDFAEKINANPASLVAVMMNLGEMVTATQSVSDETLELLAGEMNYTVQIVSPEEEDRELLESFDIEFGEDEGSEEDLVVRPPVVTVMGHVDHGKTRLLDAIRKTNVIAGEAGGITQHIGAYQVATEVNDEERKITFIDTPGHEAFTAMRARGARSTDIAILVVAANDGVMPQTVEALNHAKAADVPIVVAVNKIDVEGADPTKVRGQLTEYGLVAEEYGGDTMFVDISAKQGLHIDSLLEAVVLTADASLDLRANPNQDAQGIAIESRLDRGRGAVATVLVQRGTLRVGDTMVVGDAYGRVRAMLDDNGNNVAEAGPSMPVQVLGLTNVPGAGDNFIVVEEDRTARQIAEKRAARERNAAFAKRTRRVSLEDLDKVLKAGEVQQLNLIIKGDASGSVEALESSLLQLDVGEEVDIRVLHRGVGAVTESDIDLAMGSDAIVIGFNVRAAGRAAQMAEREGVDVRYYSVIYQAIEEIEAALKGMLKPEYEEVELGTAEIREVFRSSKLGNIAGVLIRSGEVRRNSKARLIRDGKVIAENLNIEGLRRFKDDVTEIREGFEGGINLGNFNDIKVDDVIATYEMREKPRA
>NZ_CP010849|5706444:5756901|5716580_5716862_+|WP_078969317.1|DBSCAN-SWA
MSGRTPARACPERTCVGCRERAVKNELLRIVAVEGACVPDPRGTLPGRGAYVHPATVCLDQAVRRRAFPRALRVPGPLDAKALRHHVEQAQGC
>NZ_CP010849|5706444:5756901|5748486_5750247_-|WP_044384539.1|DBSCAN-SWA
MTVGAATPDIASWPPLDDDKRAFGQQLLDWAADDSGDRPRLCLLRGAEGSGKSRLLAWFLAGAAGHPRTTVHATVPAEGLTAETFAWELGRQLGYGPLPPARLLDRIGRDQRPLLLLVPDAHRAGAGPADLPAADPAALVADLLDPLLSLPQLRAAVETGDLGLLPADGAEIIDLGGRTAPPPGRRAPARATFAELLATVPFTPDGRPDWSRAPGPARRHILDAALRADDSEAAVRGLLADPGFLVHGSATALTALLADERVPAPGSLRRVWRRAAPELTGHHTDGVERAALLHAAAVGTDPVLAEYLRPLAQQHRWTAVWAQPDLPVAALATVPGEEHRLAAADATGRLRTHHMNTGTPAGVIGSPPYVRPVSVAARDAHSMLLLDQTGTLLPVAPEDDAAGLRHIAEHHGAAALTREETQVTALGGDPRSPYAVVGDRGGSLHLWSLGDGQDAPRSHRVHEQPVRAATCLRIAAGGPTFVFSAALDGSVRLWETSTEPMPVPVQQRSYLATALAAADTPAGPVLAVAWSDAELHLWHVPSGRMRALPLLHTCHALALTSRGVLVVGGPDGLYAVRLRLDTLWEP
>NZ_CP010849|5706444:5756901|5713608_5714079_-|WP_044384485.1|DBSCAN-SWA
MSEAREPELNALQAALAAEHAAVYGYGVVGGRIGAERRAQARAAFDAHRARRDALVRQVRARGGEPVAAAAGYALPFPVPDAAAAVRLAAELEDRVAGVYSDLVRAAAGERRAAAADALREAAVRAVGWRGGSVAFPGLAERVGAAGPSAPASPPA
>NZ_CP010849|5706444:5756901|5743535_5744993_+|WP_078969321.1|DBSCAN-SWA
MGEKGIDNFQYVEANQCFAGEHTTKFGLEYDMDQMKDMVRDADPGTVKKVAQGWAALNKDLVGSGGIKETFDAAVEHVLAHWEGKSADLFRERARIVGQKITDSAKYAHYASQSLEGAAETLAKIKPIVLAMEKPSKLSSAGDFIGDLGDRDASGADNALKSGASSSEALAKNEGSLSAGREAQLKMAEQMEILGAAYNRRAMEMGSWKRTGGVEDGENYPGDPGGIPPAAVVVPTGNARGPQGATGGSPRGGQAGTISPSKPVAPPAGITGGAHKPIAPQAPQVGTAIDGVSGGRTGGPSVGGPSTAGGGTTGGSVPGGSGGGIVGAVPGAAGAGAVRGGAGGRAGAGGTVGRGATGAGAGGMAGRGAAGAGAGAAGGAAKGGTARAGGLARQSGGVVGGTPRTGAGAGAGAGRGTAGGSGLHRSRGAAGGASAVRKGGMVGVPGARNGRHQDEERREGERPDYLVEDEETWTPQTNAAPRVIE
>NZ_CP010849|5706444:5756901|5730027_5731071_-|WP_044388454.1|DBSCAN-SWA
MTADASPAPAGGTETAASRGRGRGAYPRYVAGKVAGAAVSLLAVLVTSFFLFRLIPGDPVKYMTGGRPVSAEQLAAYREQFGLDLPLWQQFAEYCGKALTGDLGTSYQFNTPVLDKITEALPNTLLLTGTAFVLYTALGVFLGTRSAWRHGRLGDRLHTGLALTLYSIPSFWLGLLLIIVLSVGAGPLPGLFPTGGMESGGEEGFAYVVDVAHHLVLPVMTLVAVEYGQTLLVTRSALLDEMGSDYLTTARAKGLRDDLVRRRHAVPNALLPTVTLVFINLGRTVAGVILVETVFSWPGLGGLFYQALSVPDLPLVQGLFFVFAAAVILMNTLADLIYPLLDPRVGR
>NZ_CP010849|5706444:5756901|5747075_5748299_+|WP_052808779.1|protease|DBSCAN-SWA
MFAAAPYATADQVREDQWALEALNAESVWKLSKGSGVTVAVIDDGVNASHIDLQGNILEGKDFMDGGSASPNPGDNHGTAMASIIAAHGHGANDGVIGLAPEAKILPIREFGTDGPGLPVSIRFAVDNGASVINVSQCFGSNSSEEVEKVSDAVAYALSKDVLVVGGAGNDGNASKCYPAASPGALGIGAVANDGQIWENSNSGAHVSLTAPGKNIVAAKGTGDGYRTGAGTSDATAYVSAAAALLRSQFPDLTAGQIANRLVKTAVLPEAEKGLSLPDERYGYGIIQPLAALQEDIPVGSKYGPLAVPDSLKAKTATPEIGMSDEEQEKADRKALIIWSVIGVVGLAVVGLIVFLIVRRSRRNRGNGGGYPQYGGQSNPYGQPVSVQHNPYQQQPMPPHGQWPPRQ
>NZ_CP010849|5706444:5756901|5754304_5754682_+|WP_044384548.1|DBSCAN-SWA
MSTEEQILHLHLPTLLRHGIGAGAAQRPALFGEGAVAAAVTLDRLGVQPRAVAFLAKTVRSGGVRYAAGLEEPFPGEEASRTAREWLTGAASVAADTDDDETVARWFEAVAEILALRHRTSAARR
>NZ_CP010849|5706444:5756901|5733262_5736067_-|WP_107071070.1|DBSCAN-SWA
MHSDRDGMRVGWTTPSDDQSDAEAAVETTGEFTIDYAAPAWYTQSASTGGEQAAPAPAPAHTPGPTDTTGSGDSGPAAPPAPAAPPAVAPAPGPVPAQGQVPGPGQAPGAGGHVPGQVQAPAAGGHVPGQGQVPAPGPLPGSGSGPATGAGGVTPPPPTGSPIAAPPPPPGSFPLAPSGAPVTSAASDASGAAASGAPEGTAPAAGEVSAGEAAPAPAPGGAQAPGEAEPSAGPGGAEAASGTGEQETTEQGTDDGAASRPEPQDGEGAAAPGPEDGASPAADPGDDGEAQDAEPAGDAPAAPSGAPEQTESPQQDASSGWRPPPAPQGAVPPLPPQFPSAATGGAPAAAPGWPAAAGQPQPPMAQPADPSAPAQPPAAAAPPQAPQPAPGGWPAAPGQPPAPPGGYGFPPSAPQGGYGYPQQPVPQPPQPGYGYPQPPQPGYGYPQQPVPQPPQPGYGYPQQPPFAQPQQPQQPPAQPGRPGQPLPPPAQGQPQPAQPQPGQPPVPGQPPHAQHPYAQPSGQPGVDPRTGAPWPQAVQHDQREQISPGAPLGYNAAVELTSDRLVNTKRQKAKSSRPTPGGSRFKLGGKKEEQERQRKLELIRTPVLSCYRIAVISLKGGVGKTTTTTALGSTLASERQDKILAIDANPDAGTLGRRVRRETGATIRDLVQAIPYLNSYMDIRRFTSQAPSGLEIIANDVDPAVSTTFNDEDYRRAIDVLGRQYPIILTDSGTGLLYSAMRGVLDLADQLIIISTPSVDGASSASTTLDWLSAHGYASLVSRSLTVISGVRETGKMIKVEDIVTHFEQRCRGVIVVPFDEHLAAGAEVDLDMMRPKVREAYFDLAAKVAEDFVRAQQEQGLWTSDGNPPPTMAPPMPGYPSAGGQPFQGHPGAQPGQPWQPGPQPGYAPNPYGPPGGEQPGAGMPPGQLPPQQ
>NZ_CP010849|5706444:5756901|5745147_5746437_+|WP_052808778.1|protease|DBSCAN-SWA
MAAAPIASADQTRRDQWALETLQAESAWNISKGEGVTVAVIDTGVNAQHIDLRHNVLKGKDFIDGDDDASPESTDAQPSHGTGMASVIAGHGHGPGAADGVMGLAPAAKILPIRVNLEGNSGFADEIHYAVDNGASIINISMILQDSQYKDGASAEDLEAVAYALEKDVLIVAGAGNDGKGGDLPFPANTPGVVAVGGVDRTGSFWEDSNYGPEVLLTAPATRIVSAGWPGNKLRISDGTSDSTAYVSAAAALLRSKFPDLTAGQIANRLVRTAALPESAKGLTLPDEKYGYGVIRPLAALTEDIPVGSKYGPLKVPGAEGSSAAPGTGKSDTDHAAENKEADQKQLVFFVVLGLIALAVIGLIVFLIVKLSRRNKNKTGGSGGPAGYPQYGQHPVSPQPHAYQQPVSPQQNPYQQQSPPPHGQWPPQQ
>NZ_CP010849|5706444:5756901|5726092_5727049_+|WP_044384502.1|DBSCAN-SWA
MQRWRGLEDIPQDWGRSVVTIGSYDGVHRGHQLIIRHAVDRARELGVPAVVVTFDPHPSEVVRPGSHPPLLAPHHRRAELMAELGVDAVLILPFTTEFSKLSPADFVVKVLVDKLHAKAVVEGPNFRFGHRAAGNVEFLAEQGKTYDFEVEVVDLYVTGRAGGGEPFSSTLTRRLVAEGDVAGAAEILGRPHRVEGVVVRGAQRGRELGFPTANVETLPHTAIPADGVYAGWLHAQGEAMPAAISVGTNPQFDGTERTVEAYAIDRVGLDLYGLHVAVDFLSFVRGQAKFDTLEALLEQMAADVERCRRLVAEAGKPA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044384475.1|5706444_5707749_+|protease	site-2 protease family protein	NA	NA	NA	NA
WP_044384477.1|5707934_5709092_+	flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA	NA	NA	NA
WP_044388450.1|5709192_5710041_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_044384479.1|5710094_5710625_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_044384481.1|5710746_5712447_+|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_044384483.1|5712606_5713509_-	kinase	NA	NA	NA	NA
WP_044384485.1|5713608_5714079_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_044384487.1|5714075_5714603_-	hypothetical protein	NA	NA	NA	NA
WP_029380840.1|5714932_5715442_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_044384489.1|5715444_5716431_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_078969317.1|5716580_5716862_+	YlxR family protein	NA	NA	NA	NA
WP_078969318.1|5717025_5720061_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	5.3e-18	23.2
WP_029386804.1|5720252_5720546_+	DUF503 domain-containing protein	NA	NA	NA	NA
WP_029386803.1|5720601_5721048_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_044384498.1|5721044_5721950_+|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_044384500.1|5722208_5725946_+|protease	serine protease	NA	NA	NA	NA
WP_044384502.1|5726092_5727049_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_044384505.1|5727045_5728125_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-17	36.8
WP_044384507.1|5728121_5729123_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.0e-15	32.2
WP_044384509.1|5729119_5730031_-	ABC transporter permease	NA	NA	NA	NA
WP_044388454.1|5730027_5731071_-	ABC transporter permease	NA	NA	NA	NA
WP_044384511.1|5731111_5732959_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_107071070.1|5733262_5736067_-	AAA family ATPase	NA	NA	NA	NA
WP_044384514.1|5736372_5736690_-	DUF397 domain-containing protein	NA	NA	NA	NA
WP_044384517.1|5736930_5737758_-	hypothetical protein	NA	NA	NA	NA
WP_078969319.1|5737757_5739089_-	type VII secretion protein EccE	NA	NA	NA	NA
WP_044384523.1|5739284_5740850_+	type VII secretion protein EccB	NA	NA	NA	NA
WP_044384525.1|5741073_5741394_+	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_044384527.1|5741459_5741753_+	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_107071224.1|5741940_5743179_+|protease	type VII secretion-associated serine protease mycosin	A0A217EQY2	Bacillus_phage	5.1e-36	37.1
WP_044384531.1|5743181_5743496_+	hypothetical protein	NA	NA	NA	NA
WP_078969321.1|5743535_5744993_+	hypothetical protein	NA	NA	NA	NA
WP_052808778.1|5745147_5746437_+|protease	type VII secretion-associated serine protease mycosin	A0A217EQY2	Bacillus_phage	1.9e-25	35.0
WP_052808779.1|5747075_5748299_+|protease	type VII secretion-associated serine protease mycosin	NA	NA	NA	NA
WP_044384539.1|5748486_5750247_-	hypothetical protein	NA	NA	NA	NA
WP_044384542.1|5750283_5751117_-	hypothetical protein	NA	NA	NA	NA
WP_044384544.1|5751161_5751743_-	hypothetical protein	NA	NA	NA	NA
WP_063856826.1|5751825_5753526_-	hypothetical protein	NA	NA	NA	NA
WP_044384546.1|5753923_5754286_+	ESX-1 secretion-associated protein	NA	NA	NA	NA
WP_044384548.1|5754304_5754682_+	hypothetical protein	NA	NA	NA	NA
WP_044384550.1|5754815_5756399_+	peptidoglycan-binding protein	NA	NA	NA	NA
WP_052808676.1|5756415_5756901_+|protease	protease inhibitor I42 family protein	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP010849|6129052:6153047|DBSCAN-SWA
CATGCCGACGTACCTCACCCCGGGTGTGTATGTGGAGGAGGTGCAGTCCGGTGCCCGGCCGATCGAAGGCGTGGGTACCGCGGTCGCCGCGTTCGTCGGATTCGCCGAGGCCGGGCCGTTCCACACGCCGACCCTGGTCACGAGCTGGGACCAGTACACCCAGCAGTTCGGTGGCTTCACCGAGGGCACCTACCTGGCCCACGCGGTCTACGGGTACTTCGCCAACGGCGGCGGCGCCGCCTACGTGGTGCGGATCGGGGGCTCCGCCGAGGACTCCTCGGCGCCGGCCGCCGACGGGACCGGCCGGGGGCAGCAGGCCGGTGCGCCGCGGCCGGTGGAGCTCGGCGGGTTCCTGGTCGCCGCCCGGCCCGGCGCCACCGGGGTGTCGGTGGAGATCGCCGACGCGCCCGGCGAGGAGCCGCCGGAGGACCGGTTCAGGTTCCTGGTGCGCCAGGGCGGCGAGGTGGTGGAGACCTACGAGGCCTCCACCCGCAAGAGCGTCAAGGGGTATCTGGTCAGCCAGGCCCGCAACTCCAAGCTGGTCGAGGTCACCGAGCGGCGCGACGCCCCCCAGGCCAGGCCCGCCGCCCAGACGGTGGCGCTGCCCGACGCCCCGGCCGCACCCGGTGCGGTGGCCCGCCTGGACCCGTCGGAGTACGTCGGCGACGCCGCGGCCCGCACCGGGTTCGGCGGCCTGGAGACCATCGACGAGATCACCATGGTCGCGGTGCCGGACCTGATGAGCGCCTACCAGCGCGGCGACATCGACGCCGAGGGCGTGCGCACCGTACAGCTCGCCGTGATCTCGCACTGCGAGCAGATGGGCGACCGGGTGGCCGTCCTGGACACCCCGCCCGGCCTCACCGCCCAGCAGGTGCGCACCTGGCGCAACGACGAGGCGGGCTACGACTCCCGGTACGCCACCCTCTACTACCCCTGGGTGCGGGTCTTCGACCCGGCCGCCGGACGCAACACCACCGTCCCGCCGAGCGGCCACGTCGCCGGCGTGTGGGCGCGCAGCGACGCCGAGCGCGGTGTGCACAAGGCGCCCGCCAACGAGGTGATCCGCGGCGCCGTGGACCTGGAGATCCGGCTCAGCAAGGGCGAGCAGGACCTGCTCAACCCCATCGGCGTGAACTGCGTACGGGCCTTCCCCGGCCGCGGCGTCCGCGTGTGGGGGGCCCGCACCCTCTCCTCCGACCCGGCCTGGCGCTACCTGAACGTGCGCCGCCTGTTCAACTACCTGGAGGAGTCGATCCTCCTGGGCACCCAGTGGGTGGTCTTCGAGCCGAACGACGACCGGCTGTGGTCGAGCATCCGGCGCAATGTCGCGGCCTTCCTCACCGAGGAGTGGCGCCGGGGAGCCCTGTTCGGCCGCACGGCCGAGGAGGCGTTCTACGTCAAGTGCGACCGTGACAACAACCCGCAGGAGTCCATCGACCAGGGCCGGGTCGTCTGCGAGATCGGCGTCGCGCCCGTCAAGCCCGCGGAGTTCGTGGTCTTCCGGCTGGCCCAGTTCTCCGACAGCACCAGCCTCATCGACGAGTGACCCGCGGGTCCGCAAGGAAAGGTGACAGACAGTCATGGCAGAGGGCGACGCTCTTTCCACCCACGTCTTCGGCGTGCAGCTCGGCGGCTATCTGGTCGAGTCGATCCAGGAGATCAGCGGGCTGACCGTCGAGGAGGAGGTCGTCGAGGTCCGCCAGGTCAGCGCGACGGGCAAGCAGATCATCCGCAAGCAGCCCGGCGCCCGGCAGGCCGGTGAGATCACGATCACCCGGGGACTCGACCAGAGCAGCGAGTTCACGAACTGGATCAAGGAGACCCTCAACAAGGGGGCCGTGAACTCCGCGCGGCAGAACCTCACCATCGAGATCAAGGACTCCGAGGGCACCACGGTCCGCCGTATCCAGCTCATGCAGGGCTGGGCCTCCAAGTGGGAGGGCCCCTCGCTGAAGGCGGGCGAGTCCTCCGCGGCCACCGAGACCGTCACCATCGTGTTCGAGGAGATCGTCGTCGAATGAGGCGCCGTACGGTGACGGCGGGCAATCTGGAGGAGATCCTCCAGTTGACGACGCCCGCCCCGCAGACGGAGCAGGAGGCGGTGGCCCCCGCGGCCCCGCCGCCGCCCCGGGAGGAGCACGGCCTGCGCACCGAGTTCGAGTTCGAGCTGCCGCGCGGGTACGTCGACGAGGCGGGCGTGCTGCACCGCGACGGCGCGATGCGCCTGGCCACCGCCCGCGACGAACTGCGGCCCCAGATCGACCTCAGGGTCAAGGAGAACCCGGCGTACCTGAGCGTGGTGCTGCTGAGCCAGGTGATCACCCGGATCGGCACCATCACCGACGTGCACGCCGGGATCGTGGAGCGGATGTACGCCACCGACGTGGCCTTCCTCCAGGACTTCTACCGTCGCGTCAACAGCGAGGGGCACACCCGCGCGGCGGTGACCTGCCCCCATTGCGAGGGCGGCTTCGAGGTCGACCTGTCGGGTGGGCGCCTGGGGGAATCGTGACGTACGCCCTTCCCCGGCTCCGGGAGGAGATCGCGTACATCGCGTACCACTTCCACTGGCAGCGCGAGGAGATCCTCGACCTCACCCACGGCGAACGCCGGCAGTGGGTGGCGGAGATCGCCCGCATCAACACCCGTATCAACGAGAGCGGTTAGCACATGGCATGGCGGGACAGGCTGCGCCGCCGGGCCGCCGGAGCGGGCGGTCCGTCCGGCTCCGGGGCCGGAGGCCGGGACAGGGGAGCCCCTGACGCCCGGGGCTCCGCCCTGCCCGGTCCCGCGTCGCCGTCCGGGCCGGATTCCGCCGGGGCCGGGTCCGGGTCCGGTGCCTCCGGGGCGGGTACTCCGGTGCCCGGTGCCGCCGCGTCGGCTCCCTCGGTTCCCGGCGACTGGGACGGCGGATGGCGGCGCACCACGGCGCCGGAACTCACCCTGTCCCGCGCGCCGTTGGGTGTCAGCGACGGCCTGTCCTTCCGGGCCGGCCTGACCGCCTGGCAGAACCCCTCCTTCGGCACCGGCCTGGGGCACGCCGTGCTGCCCACGGCCCCGGCGGGCGTGGTGCGGGGCGTCGTCGGCCCGGCCACCCCCCGCACCATCGGCACGGGCGGAGGCCCGCTGCTGCTCGGCGCGCCGCGCGGGCACGGCGCCGGGGAACCACTGCCCGCCGCCGAGACCAGGCAGGCCGCGGACGGCGGGGACCGGCGGGACCCGCCGCCCGCGACCCCGCGCGGGGCGCGTCAGGGAGGACGGGCGTCCGCCCGGCCCGGCCCGTCGTTCCGGCCCCGGCCGTCCCCCCAGCCCGCTCCGTCCGGCCCAGCCGGTTCGCCCGGTTCCACCGAGCCGGCCGGTACGTCCGGTCCGGCCGATGCGCTCACCGGCGGCCCGGGCGGCGCGCCGCGGTCCCGGGGCCTGCTGTCCACCGGCTCCGCCGGAACGCTGCCCTCGGCGCCCCCCGCCGTCCAGCGGGCGGAGCGGCCCGGCGGCGGACCGGCCCCGACCGCCGACATTCCGCTGGTCCGGCGGGTGGCGGCGGTCGCCCCCGGTCCGGGCCGGGACGAGCCGGTGGTCCAGCGTGCCGCCCGGCGTGCCTCCGACGGGCCGTACGCCCCACAGCCACAACCACAAGCCCAGGCACAGGAGCGGACCCAGACGCCGGCACGGCCAGGGACACCGGCCGCGCCGCGCACGCGTTCCACCGGGTCCGGGCCGGACCCGAAGCGCACCCCCGGGACGCCGTCCGGCTCCGGAGGCACACCGCCCGGCCGGGCCGCCCGGAGCGGCGGGCCGGAGCGGGCGGGCGCGTCCCGGACCTCTGACGCCTCGGCTGCTTCCGAGGAAGCAGCCGCCGGGGCCGGGGGCTCTTTCCCGGCCGCCCGTGTCCGCCCGCTGGGGGGCGCGCTGACCGTCGCCCGGCGCCCGGTCGGACCCGTGCGCCGGGTCCGCGCGGTGCCGCCCGCCATGCTGCCGGCGCCCGGCGACCGCGCCGACGGCGGCACCGCCCCGTCACCCGCCGAAGCTGCCGCACCTGCCACCGGTCCGGTGCAGCGCACCGCCCGGAGCGCGGAAGACCGCGCGCCCCTCGGCGCGCCGCTGAACGCCCTGCCCGCCACAGCCCTGCCCGCCACGGCGCTGCCCGCGGCGGACGGTCCCGCCCGCCCGTCCGCCTCCGCCGCCCGGTCGGCGACCGGCGACCCCGCCGCGTCCGGCCCGGCGCTGCCCGTCGTCCAGCGCCACGCCCAGGACGGCGCGGGAACGCCGGGGCCCCGCGATGTGGGGGAGGAGCGCACGGCCCACGGCGGTCCGGCGGCGCGGGCCGGTGCCACGGACCCGGCGCCCGGCACCGGCCGCGGCGGGGCCCGTGCCCGCGGCGGGCTCGGCGCGCCGCTGTCCGCGCTGCCGCCCAGCGCCGAACTGCCGCGTTCCGCCGCGTCGGGCCGCCCCGCTCCGCGTACCGGGTACGGCCCGGACGTCCAGCGTGCCCCGGCGCGCCCGGACCGCGGCGCGGACACCACGTCGGCGCCGTCCCGTGCGGACGGCGGCCGGACGGAGGCGCCGCGTACCGCCCCCGGTGCGGCCCCGCCGCCGTCGGCGGCAGCGGACTCGCCGCCGGGAGCCGCGGAGCAGACTCCGCTGCTGGGGACGCGGGAGGTCCAGCGCCTCGCGGCGCCTGCCGACGAGGGGGCCGCCCGACCCGGCGCCGCCGACCCCGGCCAGGCCCCCGCCAGGCCGCTGGTGAAGCCGTCGCCGGACGGCGCGGCCCGCGTATCCCGTGAGGCCAACGGCGCCGTCGCGGCGGCGGCCGACCCCCGCGGTGCCCGCCCGGCACCCCCCGGCCCGGGCGGGCAACCGCCCCGGGAACCCGTCGTCCCGGTCCGCCCGGTCTCCGCGGCCCGGCCCGCGCACGGCGGTGCGGGCGGTGCGGCCGGTGCGGGCGGCGCCACCGTACGGACCGGAGCCGGGACCGGCGCCGGGGCCGCCCCGTCCCCGGGCGCGGCCGGCCGAGGCGCGCTCACCGTGAGCCGAGCCGCCGTGCTCCCGGCCTCCCCGGCCTCCCCGGCACCTCGCACCCTGCCCCTGCTCGCCGCGCGCCCGCTGCGTACGGAGACCCGGCTCGCGGAAGGGGCGGCTCCGCCCGTCGCCTCCCGGCCCGGGGGCCGTCCCGTGGTGGCCGCGCGCTGGACCGGCGCACCGGCGGCGGTGAGCGACGCCTCCCGCAGCGGGGCCGCGCCGTCCCCGGCCCCGGTGCCGGGCGCGCCCGCACCGTCGGCGTCATCGGGCGTGCGGTCCGCGGCCGTGCGCCCCGGGCCGTCCGCACCCGGCACCGGCCGGGCCGCGAGCGACGGTTCCGGCCGGGGCGTCCCGGTCGTGCGTCCCGCACCGCACCGGGGAGGCGCACCCGGGACCACCGTCCAGCCCGCCACCGCACCGGCACGGTCCCTGCCGGTGGCCGGGGCCCGGACGCCCACGCCCGCGACGGGCCCGGCCGCCACGGTGCCACCGGCCCCGTCGGCCTCCGTCCCGGTGGTCCGTCCGCGTGCCGTTCCCGCGGGGCCCGGACCGGCGACGGGCGGCGAGAAGGGCCCGGTCGCGCCCGTGGTGCAGCGGAAGACCGCCGGTACCGCGCAGGCCGCCGGGGGAGCGCCCCCCGCCCGGCCGCGATCCGCCGCCCCGCCGTCCGCCTCCGGTACGACGGCCTCCGGCACCGCGCACCGGGCCGGGGCACCGCCGGACCCGGGCCGGGACCGGGACGACCTGGACGACCTGGCGCGCCGCCTGCTCGACCCGGTGTCCCGGCTGCTGCGCGCCGAACTGCGACGCGGCCGGGAACGCATGGGCCGCCCCCACGACCGCCGCCGCTGACGGCGACCAGAACCACGGACGACCCGGAAGCACGGACGGCAGGCACGTCCCGCACGGCACGGAAGTCCCCAGCAGCACGGAAAGCACGGAAAGCACGGAACGGATGACGGACCGATGACCGACAGCATCTTCGCGACGAGCGTGTTCTTCCGGCTCGCGATCGGCGGCAACGACCTGGGCGCCTTCCACACCTGCTCCGGCATGGGCGCCGAGGTCGAGATGGAGACCTACGCAGAGGGCGGCAACAACGGCTTCACCTGGAACCTGCCGGGCCGGGTGACGTGGTCCAACATCACGCTCACCCGGCCGGTCACCGCCGACACGGCGAAGATAGGCCGCTGGCTCGACGAGACGCTGCGGCGGGTGGAACCCAAGGACGGCGAGATCGTGGCCCTGAAGCCGGACCTGAGCCGGATCATCAGCTGGCAGGTGTTCGGGATCGTCCCGGTGCGCTGGCAGGGGCCCTCCTTCGACCCCGCCAGTTCCCAGGCCGCGGTGGAGACCCTGGAGATCGCCCACGAGGGCCTGAGGCCCCTGTGACCGGCCGCCGCGCGGTCCACCGCCCCGCTCACCGCCACGCGACGCCCGCCGGCGTCCACCGGCTCCCGCCACCTGTTCCCCTCACCCCCGCTGTTCCCCTCGACCCCGCCCCCGGGCACCGGCCCAGAAAGGAGGCTCCGGGATGTCCCCAGCGGTCCGCTCCAGCCGGGCCAGGGCCCAGCTGACCCTGAAGGAGCCGCCGGCCTCGGTCGGCGCCAAGCCCGGCGGCACGATCGCCCGGCTCGACCTCCAGTTCAACCCCTCCACCCTGGAGCTGCGCAAGACCACCGAGTGGCGGCGCTCCCCGTCCCGGATGGCGGAGGAGTCCGCGCTGCCCGAGTTCGTCGGCAGCGGCCCGCGCACGCTGAGCCTGGAGGTGTTCCTGGACGCCACCGCCACCCATGACAACTCCGTGGAACAGGCGGTGGAGAAGCTGATGAAGGCATGTGTGCCCACCCCGGCCAGCCTGGGCCGCAAGAAGCCCGCCAGCCCGTGGGTGCGGTTCGAGTGGGGCACCGCGCGGACGACGTCGTTCGACGGTGTGCTGTCGAGCCTGTCGGTCACCTACACGCTGTTCGACGTGGACGGCCGGCCGCTGCGGGCCACCTGCGCGCTGACCATCGAGGAGGCGAGCGTCGACACGCCGGGACAGAACCCGACCTCCGGCGCGCGCACCGCCCGCAGCACCCACACCGTGGTGGCCGGCGACAGCCTCGCCCTGCTGGCCTGGCGCGAGTACGGCGACGCGACGGCCTGGCGGGTCATCGCGGAGGCGAACGACATCGACGACCCGATGGCCCTCGCGCCCGGCACCGAACTGGTGGTGCCCGGGCTCAGGGACGAGGGCGCTGAGGAGGAGCGGTGAGCACAGCCGAGGCACAGGGCGGCCGGTCGTTCGCGGCCGACCCGGTCGTGGAGGCCCCCGCCGAACTGCCGAAGATCTGGGCGGCGCAACTGGTGAGCTGCGTGGTCGACGAGAACGTGGGCCTGCCCGACGCGGCGGTGCTCACCTTCCGCGATCCCGACCACGAGTTCCTGCGGACCACCGGCATCACCATCGGCACCCCGCTGCGGGTGTCGGTGGTGACCGTGTCGGGGCGGGCCCGCGAGCGGTTGTTCAACGGCGAGGTGACGGCGCTGGAGGTGGACCGGGACAGCACCGGCTCCTTCACGGTGGTGCGGGCCTACTCCAAGGCGCACCGCCTGCAACGGGGCCGCAAGGTGGTGGCGTACCGGAACATGACGGCCGCCGCGATCGTCCGCAAGGTGGCCGCCGGGGCCGGGCTGGCCTGCGGCACCGTCGAGGCGGCGCCGGTCAGCTACCGCCAGCTCTCGCAGGCGAACGTGTCCGACTGGGAGTTTTTGCAGTACCTGGCGGGCGAGAGCGGCGCGCAGGTCCGCGTCGACGACCAGGGGGTGCTCCAGTTCACCCGGCCCGAGAAGGCCGCCAAGGCGCCCGCGCCCTCGACCCCCGCGACCCGCGACCCGATGGTGCTGGAGTACGGGCGCAACCTGCTGGCGCTGCGCGCCGCGCTGTCGGCCGCGGACGGGGCCGCGTCGGTGGAGGTGCGCGGCTGGGACGTCACCACCAAGAAGCCGCTGGTGGCCCGGCAGCCGTCGGTGGTCAGCGACACGGTGGTGCCGGGCCTGAGCCCGCAGGCCGGCGCCCGGTTCGGCGCGTCGGCGAAGCTGGCCGTCACGGACACCCCGTACCGCACGCAGGCGGAGACCACGGCGGCCGCCGGCGCGATGGCCGCCCAGGTCAGCGCGGGCTTCGGGGAACTGGAGGCGGTGGCCGAGGGCAACCCCCGGCTGCGGGCGGGCAAGCCCGTGGCGCTCGGCAACGTGGGGCCGGCGTTCTCCGGCCGCTACACGGCCACGGCGGTGCGGCACGTCCTGGAACCGTACGGCGGCTACCGCACGACGGTGTGGGTGAGCGCCAGCCCCGACCGCTCCCTGACCGGCCTGGTGACCGGAGCCAACGCGCCGGGCCGCGGCCCGCGCATGCCGGGCCTGGCGATCGGCGTGGTGACCGACGTGCGCGAGCCCGGCGGCGCGGAACGCGGCGAGGTGCGCCTGCGGTTCCCCTGGCTGGACGACACCTACACGACCGACTGGGTCCGCACCGTGCAGTGGGGCGGCAAGGGCGGCGGGGGCGTGGTGAGCCCGGAGGTCAACGACGAGGTCCTGGTCGGTTTCGAACAGGGCCTGCTGGACAGCCCGTACGTCATCGGGGGGCTCTACAACGGCGTGGACCGGCCGTCGCCCCACGACGTCCCGCTCATCGACGCCACCAGCGGCCGGGTCAACCGCCGTTCGGTGGTGTCCCGTTCCGGGCACCGGGTGGAACTCCTGGACGCGAGGGCGCCCGGTCCTTCCGGGCTGCGGCTCACGACGGGCGACGAGCGTCTCGAAGTACGCCTGGACGACCGGCGCGACCGGATCGAGCTCACGGTGTACGCCGGGCGGGGCCGCCCCCTCACCTCCGTCCTGCTCGACAGGGACGGCATCACGCTGGACGCCGGGCGCGGTGACGTGACCGTACGCGGCCGCCGGGTGGAGATCGACGCCACCGAGACGGCGACGGTGGGCGGCCGTTCGGTGCGGGTCACCGGGCAGACGGAGGCCACCGTCGACGGCGGTCTGCTGGGCGTCCTCAAGGCCCGTCTCATCAAGATCAACTGAGGCCGCCCGTGTCCCTCGCGCACCAGCAGCCCGTCACCGCCGGGCCTTCCCCCGCCCGGCGGGCGGGCGCCCCGGCGCCCGCGCCCGCCCTCCCCGCAGACCACGACCGCCCCCCGGCCCTCGGGCCGGAGATCTTCCGCAAGGAGTGCCCCATGCCAGCCGCAGCCCGTACCGGCGACCCCACCAGCCACGGCGGCCTGATCAGCACCCCGCCGCCCGCCGCCGCGGCGGTGGTGGCCCGGGTGCTGATCGGCGGGCGTCCCGCCGCCGTCGTGGGCAGTCTCCACGCCTGCCCGATGCCCCCGCACGCGGCCATGGGACCGGCCAACGTGATCCTGCCGAACCCGGCCGCGCTCGCGGCGGGCACGGTACTCATCGGCGGGGTGCCCGCCGCGCGCATGGGCGACACCACCGCGTGCGGGGCCACCGTGCTGGCCGGCGCGCCGAACGTCCAGATCGGGGGCGGGCGATGAGCGACCGGTTCATCGGCCGGGGCTGGGCGTTCCCGATGCGGGTCGGGCCGACCGGCGGCATCGCCCTGGTCGAGCGCGAGCGCGAGATCGAGGAGGCGATCCGCCTGGTCCTGGCGACCGCGCCCGGCGAGCGCCCCATGCGCCCGGAGTTCGGCTGCGGCATCCACGACTACGTCTTCGCCCCCGGCGACGGCGCCACCGCCGGGCGGGTCGCCCAGCAGGTGCGCGAGGCCCTGGAGCGGTGGGAGCCGCGCATCGCGGTCGACGACGTGGTGGTCGCCTACGACACGGTCGAGGCGGGCACCCTCTACATCGACGTCCACTACACCGTGCGCTCCACCAACGACCGGCGCAATCTGGTCTTCCCCTTCTACACGATCCCCTCCGACGAGGGCGGCGGGGAACGGGGCGCCGCCTGATGGCCCTGCCCTCCCCCAACCTGGACGACCGGCGGTTCCAGGAACTCGTCGACGAGGCCAAGCGGTACGTCCAGCAGCGCGCACCGGAGTGGACCGACCACAACGTCTCCGACCCGGGCGTCACGCTGATCGAGACCTTCGCCTACCTCGTGGACCAACTGCTGTACCGGCTGAACCGGGTGCCGGACAAGAACTACACCGCCTTCCTCGACCTGCTGGGCATCCGCCTGTTCCCGCCGGCCGCCGCCTCGGCCGACGTCGACTTCTGGCTGTCGGCGCCGCAGCCCGACACCGTCGTCCTGCCCGCGGGCACCGAGGTGACCACCACGCGCGGCGAGACCGACGACGCCGTGGTGTTCACCACCACCGGCGAACTGCACATCGTGCCGAGCGAGTTGACGCGCCTGGTGACCGCTCCCCGGGCCGGCGAGCAGACCGACCGGACCCGCACGCTCGCCGAGGGCCGCGACATCCCCTGCTTCCAGGCGGCGCCGGAGCCGGGCGACGCGCTGCTGTTCGGCCTGCCCACCGCCGTGCCGCGGTGCATCGTCGCGGTACGGCTGGACAGCCGGGTGGAGGGCGTCGGCGTGGACCCCCGCCAGCCCCCGCTCGTGTGGGAGGCGTGGCACGGCAGCGGCTGGCAGGTGTGCGAGACGGGCCCGGACACCACCGGCGGACTGAACCGGCCGGGCGAGGTCATCGTGTACGTACCGGCCGGGCACCGCGCGTCCGTCATCGGCGGGACCCGGGCCGGCTGGCTGCGCTGCCGCGTCACCGAACCCGAGCCCGGCCAGCCGTTCTACTCGGAGTCCCCGACGGTGCGCGAGGCGTCGGTCTTCACCGTGGGCGGCACCATGTGCGCCGAGCACGCGGTGACCGTGACCGACGTGCCGCTCGGCACCTCGGAGGGGGTCGCGGGCCAGACGTTCCGGGTCGGCCGCCCGCCCGTCCTCCTCGACGGCGCGCCCCCCGTGGTGGAGGTGTCCTCGGCCGAAGGGTGGCAGCGCTGGGACGTGGTGGAGCACTTCGGCCGCTCCGGACCCGCCGACCGGCACGTCCGGGTGGACGCCACCACCGGGGAGTTCGCCTTTCCCCCGGCGCTGCGCGAGCCGGACGGCACCCTGCGGCAGTGCGGCGCGGTGCCCCCCAAGGGCGCCCAGGTGCGGGTGGCCCGCTACCGCACCGGCGGCGGCCCCGCGGGCAATGTCGCCCGCGGCGCCATCTCCGTGCTGCGCAGCTCCGTCCCGTACGTCGCCCGGGTCACCAACCGGGAGGCGGCGCGCGGCGGCGTGGCCGGCGAGACCGTCGCCAACGCCAAGCTGCGCGCCCCGGAGGCGCTGCGGATGCAGGAGCGCGCGGTGACCGCCGAGGACTACGAGATCCTCAGCCGCCAGGCGGCGCCCTCGGTGCGCCGGGTCCGCTGCCTGCCCGCCGCGGACGACCCGGGCGCGGTACGGGTGCTGGTGGTGCCGGACGCGGTGCCCGACGAGGGCGACCGGCTCCGCTTCGAGCAGCTCATCCCCTCCGACCGGGTCCTCCAGGCGATCACCTCCTGTCTGGACGAGCGGCGCCTGATCGGCACCCGCCTCGTGGTGGAGCCGCCGGTCTACCAGGGCGTCACGGTGGTGGTCCGCCTCACGGCGGCGCCGGGCGACGCCGACCGGGTGCGCGAGGCGGCGCTCGCCGCCCTGTTCGGCTACCTCGATCCGCTGCGCGGCGGCCCGGAGGGCACCGGCTGGCCGTTCGGGCGGCCGGTGCAGTACGGGGAGGTGTTCGGCGTGGTGCAACGCGCCACCGGCGACGCGCTCGTGGAGGAGATCCGGCTCTTTCCCGCCGACCCGATCACCGGGCGGCGCGGGGCTCCGTCGGACCGCATCGACGTGGGCGCGGGCGCGCTGGTCTTCTCCTACCAGCACCAGGTGGTCGTCACGGCCGCCGGGCCGGAGGAGCGGGGATGAGCCGTGCCGCCGTACCCGGGCTCCCCAGCCGGTACCCGATCGGCGGGCAACTGCCCGCCCTCTACGCCGAGGACGACCTCGCCCAGCGGTTCACCGCCGGACTCGACACCGTCCTCGCCCCGGTGTTCTCCACCCTCGACAACCTGCCCGCCTACCTCGATCCCCGGATCGCCCCGGCCGACTTCCTGGCCTGGCTGGCGTCCTGGGTCGGCGCCGCCGACGACCGGGCGTGGCCCGTGGAGGTACGCCGTGAGGCCGTCGTCCGCGCGGTGGAACTGCACCGGTGGCGCGGCACCCGGCGCGGACTGGTCGAGGCGCTCGGGCTGGCGCTCGGCGCGCACGCCGAGGTGACCGGGGACGGCGGGGCCCGCTGGTCCGGCACCCCCGGCGCCGAACTGCCGCCCGCGCCCGCCGCCGAGGTCCTGGTCCGGGTGTGGCCGGGCCGCGAGGAGCGGATCGACCCGGACCGGGCCCGGGAGATCGTCCGGGCCATGTGCCCGGTGCACACCGTCTGCCGGGTGGAGATCCTGCCCGGCCCGCCCGCCGGCGAAGGGAGGTGACGTTCATGCGCGCGTGTCCCGCCTGCGGGGCGTCCAACGGCCCGCAGGACGACTTCTGCGGCAACTGCGGGGCCTATCTGGGCTGGTCGGAGAGTGCCGCCGCGGCGCGGGGGAGCGCCGCGGAGCCACGGACCGACACGGCCGCGGACAGCGATCCCGCCCCGGTCACCGACCCGGCGCCACGGGGCGCGGCCCCGGGCAGCGGCACGACCCCGGCGGCCGTCCCGGCCCCGGACGCCGCTGCGGGCCCGCCCCCCGAGGCCGTGGAGAGCGCGGGGCGGACCGGGGAGAGCGCTGCCGCCCCGGGCACCTCCGCGCAGCCACCGCCCCGGCGCGGGGCCGCCCCCGCCCGGCCGGACTCCGCCGGGGACACGGCCCCGGCGACGGATACGGAAACGCAGCCGGAGCCGGAGCGGGCGGCGCCGACACAGCGGGAAACGGAGCCGGAGCGGGCGGCGCGGACGCAGCGGGAGACGCAGGCGGAGCGGGCGGCGGGGACGGAACCGGAGGCCCCGGCCTCCGCGCGACGGGAGACCGGCCGTGCCCGCAGGCGCTTGCCTTCGGCCCCCGGCCGGTCCGATCAGGCGGAGCCCCCGGCCCCCGGCCCGGCTCAATCCTCGGCCCGTCCCCCCGGGCAGCCACCGGCCCCGGTCGCCCCGGCCGCACCCGGCGACGCCCGGTCCGATCCCGCGCCCCGCCCGCCCTCGGCGCCCGCCGCCGACGCGTCGGCGCCGGGACCGGTGCTGCCCGTACGCCCCGGCAGGCCGGTGGCCCCGCGGCCGACGGTGCGACCGGTGGCCGTGCCGGACGACGTCACGGGGACGCCGTGCCCCGCCTGCGGCACGCCCAATCCGCCCGGCCGCCGGTTCTGCCGGCGGTGCGCCGCCGTACTGAACCCCGAGGAGAAGCCGCCGCCCCTGCCGTGGTGGCGCACCGTGTGGCCGTTCCGCCGCCGGGCGCGCGCGAGCTCCGGCCGGGCGGTCCGGCTCCTGGTGATCCTGGCCGTGGTGGCGGCCCTGTGCGCGGGAGGTCTCCTGCTGCTGCCGGCCGGGCGTGCCCTGATCGAGGACACCCGGGACAAGCTGGGCAAGCCCAAGCCGATCACGCCGGTGAGCGTGGAGGCGAGCGACGAGGTCCCCGGGCACCCGGCGCGGAACACCACCGACGGGCTGAGCAACCGCTACTGGGGAGCCTCCGCCGAGGGCGCCTCGGTGACGTACACCTTCCGCAGGCCGTTCCGGCTGGTGGACCTCCTCGTCACCAACGGCGCGTCCGCGTCCGCGCAGCCCTACGCCCGCCAGGCTCGCGCGCTGGAGCTGGAGCTGGAGGTGACCACTCAGGACGGCACACGGCACACCAGGAAGCTGACGCTCGGTGACAAGCCGGGTCCGCAGCCGGTCCCCACCGGCATCAGCGACGTGAAGACGGTACGCCTGGTGCTGCGTTCGCCCACGGGTCTGGCCCCGGGCCGTCATCTGGCCCTGGCGGAGGTGGAGTTCTTCCAGCGCTCCTGACCCGCGACCGGCGGCGGAACCGGAGCCCGTCCTCCCGGGGTCTCCGGTTCCGCCGCCGTCCACGTCGGGCCGCCGTCCGCCTACGCCGGGCCGGGCTGCGGCAACCGGTCGAACCCGGGGATGATCGCCCGCATGCGCTCCAGGGTCCGCCGGGCCGCGGGCAGCCCCGGATCGTCGGGCGTGAGCGCCATGCGCCAGTCGACGTAGCCGCAGGAGACCAGGGCACCTTCCAGGTACTGGGGGAAGGTGAGGTTCAGCGGGCTCAGGGACTCGCCGAAGTAGTGGAAGTGGACGTCGTCCCGGGGAGCGCCGCCGGGCTCCTGGAGGAAGGCCGCGCAGGCTTCCGGGGCGTAGACGTCGAAGGGCTTGACCGCCCGGAAGCGGTCGCCGCCCTCGAAGTCGTCGTACCAGGTGTCGCCCAGCCCCTCCGCGAAGACGTCCGCGAGGGGCCGGACATTGATCGATCCGAAGTCCGTGGGGGACCCGCCGCCTTCGGGGGCGGTGTACTCCCACTCCAGGCGGAACCCGTTCAGCTCGCCGTAGAACTCGGCCACCCCGACCGGAAGACGGCCCTGCACGGACGCGGTGACCGAGGCCAGCTCGGCGTCCGTGACGGGCGGCGCGACCTCGTAGGCGCGCACCGAGAACCCGGGTGTGGCGCCCAAGCGCGCCACGCGTTCGGCGATCCGCCGCCGGTAACCGGCCGTCATGCCTGCTCCTGTCCTGTCGTCACCGGTTGGCACCGGCGGCCGCCCGCCTGGGACGGTTGTCCCGGTATTCGATGGACCTGTCCTGGCTGTTGCGCCAGTTCCGGTACGCCGTCTTGTGCGCCTGGCTGATGCCGCTCGCCTCGATGAAACTCGTCTTGGCGTCCGAGGTGGCGTTGCCCCGGTACTCGGCCCAGTGGTCCAGCAGCGCGTTGCGCACGGCCGGCGTGTTCGCGGATTGCAGCAGCGCGCCGAGCGTGCCCCGGCTCTCCAGGGTGTTGAGAAGGATCACCTGATCGGGCTCGGAGTAGTACTTGACGAGTGCGTATCCCCTGTCGCCCAGGCGCTCTATCAGTTCGACTCCGGCCATGCCGATGGCCTGGAGCAGCTCCTCCCCGTAGTGGAAGACCATCTGCCGTTGTTCGTCGTCGCTCAGGCCCCAGGCGCGGAACACGCCCTCGGCCGCTGCCGCTGCCTGGGCCCCGGCCCGGTACAGCGGCTGGAGCGCCTGCGGGAAGAGCTCCTGCGCGGTGACGCCCACGCGCCCCAGGAACGCCACCCGGTCCGCCGCGGTCGGGTACAGCATGATGTACCGGGCCTGGTCGGCGCCCTCCGCGCCCCGGTAGAGGGCGGGGAAGTTGTTCAGCAACGCCAGCTTGAGCTGGTCGTTCGGTACGAGACCCAGGACCTGGGCGCGCATCTGGTCGCTGACGTTCGCCGCCCCCATCTCCTGGACCAGCTGACCGGCCGTGCCGGCATAGGTGCTGTACACGGCGACCTGAGCGGCGCTGAGGGGGTCGACGGGCAGGCTGATCGACGAGGACCACTGCCGGGCGGAGGCCGGGTCGCCCTCGACGCCCCATTCCATCGTGATGTGGTTCGGGACGACCGACGCGAAGTTCGCGCCGTTGGTGTTGTTGTCCTGGTAGCGGACCGTGGTCCTCAGCCACACCTTGTGGCCCAGCTCCACCAGGAGTTTCGCCGGGTCCTCGGCCTGCGCCGACATCTGGGAGTTGAGCTTTCCCGGGCCGGGAGCCAGGTTCAGCACATTGTGACCGGGTCCGCCGAGCCGTCCGTTGAACAGGTGCATGCGCACGGCACGGTAGGGCGCGCCGACCGGCTTCTCACCCCCCGGTGCCATCTTGGTGTAGCCCTCCTGCCTGAGCTGGGCCCAGCCGACCGGCTCGACGGAGGGGGAGTTGGCGGCCGCGCCCAGCGGCCGTCCGTGCAGGTTGTGCACCTCCACGCTCCCGGCGCGCCCGTTGTCCGCCTGGAACACCGGGTCGTCGCCCGACATGGTGCCGTCGGTCCACCGCTGGATCACCGGAAGGCCGGACCCGCCCGCCGCCGCGCGCTGCACCGGCGCCCCGGACGCCCGGCCGGCGCCCGTCTCCTGCCCGTGCGCCGGGGACGGTCCGTGCGCCGGGGACGGTCCCGACAGAGCCCGGCGCGCGGTCGCCTCGGCATCGCGTTCGAAACGGTCCGAGGGGTCCGAGACCCTGAACCCGCCGCCGTGGTCGGTGCCGGCGACGGGACCCCGCCGCTGCTGGATGACGTGGGTGAGCTCATGGGCGAGGGTGTGCGGGTCGCCGCCCCCGGCACCGAGGACGACGTGATTGCCGGAGGTGTAGGCCCGGGCGCCGATCTCGGCCGCGGACGCCCTGGCGGCGGCGTCGGTGTGGACACGGACGTCGGAGAAGTCCGCCCCCAGGCGGGTCTCCATGTCGGCCCGGGTCGCCTCGTCCAGCGGCCTGCCGGGTGCCCGCAGCACGTCGTGCACGGTGGAGCGCTGTACGGCGCGTGCCGCCTGTTCGCCCTGCCCGGGGCCGTGCGGGTCCTGGTCCCGGCCGTCGAGGTGCCCGGCCCGGCGCAGCCTCTGGACGACGGCGGCGTTCCCGGCCGCGGCCTGAAGGGCGAGCAGTCCCGCGGGGCGCTCACGCGGCGCGACCGCGGCCTTCCGGGCGGGCGCGCGGTCTCGACCGGTCCTGCCGGTCTCTCTCAGGGCCTGGTGATCGCTCAAGAACTGCTCCTGCGGCACAGGGGGTGTCAGATGCTCTGTCTACACGGTCGATCGGCGAGGATTCCAGGTACGCGAGGGCAGAGGGGGTGCCCGCACGGCCCCGAGCGCGTTCCGCCGCCCGGCAGGAACACCGCGGACACGGCCGACGGCGTCGTGCCCCCGCGGGTACGTGCGCGGCCCGACGCGTTCAACTGCGCCCGGGACCGTATCGGTTGCAGTCACCGACCGGCAGGTGTGTTCTGGAATGGCGGGTGCGGGGGCCCGTGCACGACGTTTCGCCGGAAGGAACCGTCATGATGAGCAATCGCCGTCCCGGCGGGGCGCTCGCCGCGGGCCTGATCGCAGCGGCAGCCACCTCGGCCTTCTCCCACCCCGCGCAGGCCGCTCCCGAGGCCGCGCCGAAGGCGCCCGCGCAAGCGCCGGTGACGTGCTACGCCACGTCCTGTCACGGGCTCGATCCGATCGAGACCCACTGCGTGGACGACGCGGTGACGATCGACGACGCCACCCTCGACGGACGCATCGTCCGGCTGCGGTACAGCGCGGAGTGCAGGGCGGCCTGGGCACAGCTCTGGTTCGGGAAGCCGGACGACCGGGCGTACGTGCGGACCGAGGAGGACGGACACCTCGTCGCCGTCACGAGCGTCACGGTCAGGCCGTGGGACGGGAACAGCGTCTACACGCCGATGGTGAACGACAAGGACCTCAAGGCCAAGGCGTGTCTGGAACTGCCGCCCGACTCCGACACGGCGTGCACGATCTTCTACTGAACCACCGTCAGACCGGTGAACCACCGTCAGACCGGTGAACCACCGTCAGCGGGTGTGATGAACGCCCGTCAGGCCGTGATGAAGACGTCCAGAGCCTGGGTGACGATGTCGATGGGATTGGCGTAACTCCTGGACCCGTCCATCTCCCCCGCGAAGACCATGGCCACCGGCTGACGGATCAGATCCAGGGTCCACACGATGGCGCCCGAGTCGCCCTTCAGGCTGAACGGACCGACATCCCCCTGGATGACGATCGAGCCGGAGAAGAACGCCTTGTCCCCCGAGGGATATACGACCCAGTGGGAGGCGCCCACCTCGCGGACCCGGCCCGTCGTCACCTCCGTCGTCCGGCCGCTCTTGCCGACGGCCATGTCCACCGTCGCCGCCGTGGTCGTCGCGCTGATGGGAATCTCGAGGTCGCCGAACGGGCTGGGCGTCAGCACCCTCGGGCTGACGTCGGTGGGGACCGCCCACGCCGTCGCGCAGTCGACGGTGTTGACCGGGCCGCCGAACTCCAGCCGTGCGAAGCGCTCCAGGACCGCCACCAGATCCGCCGGGCAGGAGCCGAAGTCACCGGTGGCGGGCTGGGCCACGCAGTCGCCGAGCGAGCCCAGGTTGCTGTTGGCGAGGACGTGGTTGCAGCCGATGATGAGCGTGCGCTGGTTGCGCGGCGCCGACCGCCCCGTGGACAGACAGCCCAAGGTGCCGAGATCCTCCGCGTTGGGCACGCTGACGAGAGAGATTCCACCCGGCGCCGGACGCCGCCTGGAGACGAACTTCTGCGTCACGATCGGGCCGGTGGTGACCGGGACGACGGGGACGTCCGACGTGCCGGCCGCGCGCGCTCCCATCCGCTCGACGAGTACCGAGGCGACGTCCTCGGCGTCGCGGGGCTGGTCCAGGTAGACGTGGAGCGTCCACTGCCCGGGCGCCGGCGTCTCGCGGCACGCCCAGGTGTCCGTCGGTCTGGCCCGCCCGATGCCGACGCCCTGGATGTTGGTCGTCTCGGTCAGCCGCTCGGGGGCCCCGGCGCCGCTGCGCTCATCGCCCTGGCCGCGCAGCACCTCTTCGATTCCGGCGCGCGCTTCCAGCAGGTCGGCCGGGAACAGACCGGGGTCGGGGGCCGCACGGTCGAGCAGGTCTCCCAGCTCCCTGATCTCCGCCTGTTCGCCCGAGTGGGCGAAGTCGTCGGGCGGCGGCTGAGTGGTCCGTGGCATGGCACACCTCCTGCCACCCCCACTTGCCCATGCTGGCACGGCCCGGCGCCCCGCGCGCGGCGGGCAGCGGCTCCCGGCCGGAACAGCCTGGTCGCGTCCAGTGCCCCACCCTCATCGAGGGGCCAGGCGCCATGACCACCTCTCACCTACGGCACACCCGGCCGTCGGCCCACCTACGGCACACCCGGCCGTCGGCCCCGGCGGCTACGGATTCACGCACGCGCGTGGCCAGGGCATCCCGTGGAGGCGCTCGATGTCGGAGTTGAAGCGCCGGAGGTAGCCGGCGAAGGCAGCGATGTCCTCCTCCGGCCAGTCGGCCATGATGCGGTCCAGGCTGGCGACCAGGCCCGCGCGTTCCTCGTCGAGGCGCCGTTCACCTTCTTCGGTGATGCGGAACTTGCGGGCCATCCCGCCGTCCGGGTCGGGAATGCGCTCGACCAGGCCGGCGCGCATGGCGGCCGCGGTCTGCCGGTTGAGGGTGGAGGCGTCCAGTCCGAAGGCGTCGCCCAGTTGGCCGATCGACATCGGGCCCTGCGCGCGGATCCGGCTGAGCAGGATGTAGGCGCTGCGGTCCAGGACACTGTCGGCGCGACGCCCCTTGCCCTTGTGCAGATGCATGTAGCGGCTCAGCAGCATCTGTTCGAACTCGACCTGAGCCGTGGCCCTGTCCGCGGTGTTCACGTGCCCTCTTCTCTGCGGTGCGACTCCTCGGAGCTCCCCCTTGCCATCATATGCATCAGACATGCCATGTGTTAGATACACATCGTGTGTATGATGCACAAGGCGCCCGCAGGGTGCCGCGCTCTCATCGACCGCAATAGAGGAGCCCCACCATGGACGGCCCCCAGCCGACCACCCGCTCAGGCGCTGTCGTCGCCACGCTCGCGCTGGCGGGTACCGTGGCCGCGATCATGCAGACCCTGGTGACCCCGCTGATCGCGGACATGCCGCAGATCCTGAACACCACACCCTCGAACGCGGCCTGGGTGGTCACGGTCACGCTGCTCGTCGCGGGCGTGTGCGTCCCTGTCTCGGGACGTCTCGGCGACCTGCTGGGCAAGCGGCGGATGCTGCTCGTCTGTGCCGTCCCGCTGGTGGTGGGCTCGGTGGTCTGCGCGCTCGCCTCGTCCGTCGTGCCGATGATCATCGGCCGCGGTCTGCAGGGCATGGGCATGGGCATGGTGCCCCTGGGCATCGCGCTGCTGCGCGACGTCGTCCCGCAGGAGAAGCTGAGCGGCTCCATCGCCCTGGTCAGCGCCTCCATGGGCATCGGCGGCGCGATCGGCCTCCCCCTGGCCGCCGCCGTGGCGCAGTACGCCGACTGGCGTGTGCTGTTCTGGGGGGCGGCCGTGCTCGCCCTGTCGGTCGGCACCCTGATCTTCTTCTTCGTCCCCGACGTGCCGGCCGGTGCCAAGGGACAGCGCTTCGACGCCCCCGGCGCCGTCGGTCTCGCCATCGGCCTGGTCTCGCTGCTGCTGGCGATCTCCAAGGGCGGCGACTGGGGCTGGACCTCCGGCACCACCCTGGGCCTCTTCGCCCTGGCCGTCGTCTCCCTCGCCGTGTGGGGCTTCTACGAGCTGCGCACCCGGGAACCCCTGGTCGACCTGCGCACCACCGCCCGGCCCCGCGTGCTCTTCACCAACGCGTCCTCGATCCTCATCGGCGTCGGCATGTACGCCTTCATGCTGATCGCCCCGCAGCTCCTCCAGTTCCCCGAGGCCACCGGCTACGGCCTGGGCCAGTCGATGCTGGCCGCCGGCCTGTACCTCGCGCCCGGCGGCGTCATGATGATGATCGTCTCCCCGCTCGGCGGAAAGCTGATCAACGCCCGCGGGCCCAAGTTCACCCTCATCTGCGGCGCACTGGTCATCGCCGTGGGATACGGGATCGCGCTCCCGCTGATGGGGACCGCCTGGGGCCTGATGCTCGTCGGCATCGTCATCAACAGCGGCGTCGGCCTCGCCTATGGTGCGATGCCCGCCCTGATCATGAGCGCTGTGCCGGTCTCCGAGACGGCCGCGGCCAACGGCTTCAACACCCTGATGCGCTCGCTCGGCACGACCATCGGGTCGGCGGTGATCGGTGTCGTCCTGGCGCAGATGACCATCACCATGGGCGGCCACACCCTCGCCTCCGAGGACGGTTTCCGCACCGGGCTGCTGATCGGCTGCGGCGTGGCCGTGGTCGCTGCCGCCGTCGCGCTGCTGATCCCCGCCGTACGGACCGGCACGGATGACTCCGCCGCCGCCAAGGCCCCGGCCGGACAGGAACCGGCCCGCGCCTGAGCGGGCCGGCGACGAAGCCGACCCCGTGGGCCACGTAGGCGAGCGTGCCGGCGTCGGAGACGCCCCGGCCGGCGTACGAGCGGGCCCGTCCACACCAAGGCGCGAGGTGTGCACGGGCCCGCTCGAGGAGCCGGGCCGCCGAGGGGCGGTCAGACGGTGGTCTTCGCCGACTCCTGGTCCGTGTCGTCCTCGGTGATGTCACCGGCGTCGCGGGCGCGGACGAACTCCAGGAAGGAGTTCAGCTCACGCTTGACGACGGGGGCGAGGAGGTACAGGCCGATGATGTTGATGACGGCGAGCATGAAGAGCACGGCATCGGCCATGTCGATCAGCGTCTGCAGCGTCAGCAGCGAACCGGCGATTGCGAACAGGGTGTAGACGACCTTGTAGACGAGCTCGCTCGTGCGGCTGCGGCCGAAGAGGTGGGTCCACGCCTTCAGGCCGTAGTAGCCCCAGGTCAGCACCGTGGAGATGGCGAAGAGCAGTACCGCGATCGTGAGGATGTACGGGAACCACGGCATCACGGTGGCGAAGGCGTCCGAGGTGATGGTGACGCCGCCGATGGACTCGCCCTTGCGGGCCTCGGCCCAGCTCGCGGGGTTGGCGATGACGATGGTGAGGGCGGTCATCGTGCAGATGACGACGGTGTCGATGAAGGGTTCGAGGAGCGCGACCAGGCCCTCGCTGGCGGGGTGCTTGGTCTTGACCGCGGAGTGCGCGATCGGGGCGGAGCCGAGACCGGCCTCGTTGGAGAACGCGGCACGCTTGAAGCCGATGATCAACGCTCCCAGCACACCACCGGCGACACCCTGCGGGTTGAAGGCGCCCTCGATGATGGTGACGATGCCGGCCGGCACCGAGGTGACGTGGACCAGGATCACGACCAGGCAAGCGGCGATGTAGATGCCGGCCATGGCCGGGACGAGCTTGCTGGTGACGTTGGCGATGGAGCGGATGCCGCCGAGCAGCACGACGCCGACGAGCGCGGCGACGAGGATGCCGAAGAACAGGGCGCCGGCGGAGGAGCCCGTCAGGCCGTCCTCGCCGCCGGTGACGGAGACCAGCTGCGCGTAGGACTGGTTGACCTGGAAGAGGTTGCCTCCGAAGAGACCGAAGAACAGCACGAAGAAGGATGCGAGGACCGCGAGGACCTTGCCGAGGGTCTTGCCGTTCTTGCCGAAGCGTTCCGCCAGGCCCTTGGGCAGGTAGTGCATCGGGCCGCCGGAGACGGTGCCGTCGGCGTGCACCTCCCGGTACTTCACGCCGAGCGTGACCTCGACGAACTTGGTGGCCATGCCGAGCAGGCCGCAGAGGATCATCCAGAAGGTGGCGCCGGGGCCGCCGATGGACACGGCGACGGCCACACCGGCGATGTTGCCGAGACCGACCGTGCCGGAGACGGCGGCGGTCAGGGCCTGGAAGTGGTTGACCTCACCGGCCGACCCCTTCTCGTCGTACTTTCCTCTCACCACGTCGACGGCCAGCTTGAACTTGCGGAGCTGGACGAACCCGAACCAGCCCGTGAACACCAGACCGGCGATCACCAGCCAGGCGACGATGAGCGGAAGGTCCGTACCACCGACGGGAATGGAGTAGAAGACGACGTCTACGAGCCAGGTGGCTATGGGCTCGAAGAATCCGCTGACGGCTTTGTCGACGGACGTGGTGATGGAGTCGAGTGACACTGTGGCTACCTCGATGGCGCAGTACCGACGCAGGAGAGTCTGCGTGGGGAAGATGTGCGGTCTCTGAGCGAACACCGTTGTCCGATCGGCGACCCCGGGTAACCGGTCCGTGGACTCGGACCGTGATCACCCTGGTCGTGCAGTCGACGTGTGTGCCGACTTTCCGCACTGCGGCGAGGGGTGGTGCCACCTGCGGAGTTGCGCAGTTCTACCACGACCTTTACGAAATCTTTAGTGATGTAAATCACATAACTGTAGGTGACCCGGCAAAGTCCCAGCGGGCGAGACAGGACCGTTATCCGGCCATCGATGTCCGTTCATCGGGCAACTATGACGGGGGAGACGCTCCCCGCAGGTGCTGAGTCCGAGCTTCGACGCCGTACGTATCGCGACGGGCCGCCTCGCGGTCCATGCCCGCGAGGCCGGCGGACGACTTCGGCCGGCTGTTCGTGGTCACCGCGGATGTGTTCGGCGGGACCCTAACGAGCCCGGCGGCCGAACAGGGCGCCGCGCGGTTGCGGCGGCGGGGGAGTGCCGGGCTTGAGGGGCCAGGCGAGGAGCAGGCCGGCGACGAAGCCGACCACGTGGGCCACGTAGGCGACGGTGCCGGCGTCGGAGACGCCCTGGCCGGCGGAGTAGAACGCCTGGAGGACGAACCACAGGCCCAGCACGATCCAGGCGGGCAGCCGCAGCGGCAGGAAGATCAGGAAGGGGACGAGGACCCAGACGCGGGCCCTCGGATACAGCACCAGATACGCGCCGAGGACACCGGCGATCGCCCCGGAGGCGCCGATCAGCGGATCGCCGGAGTCGGAGTTCGCCAGGGCGAAGCCGTAGGAGGCCGCGTAGCCGCACACACCGTAGAACAGCAGGAACCGCAGGTGCCCCATCCGCTCCTCGATGTTGTTGCCGAAGATCCACAGGAACAGCATGTTGCCCAGCAGGTGCAACCAGCTCCCGTGCAGGAACATCGCCGTCAGGACGCTCAGCTCGGGCGACTTGTCGTAGCCGGGCGGTGCGATCACACAGCCCGCTCCCTGCGGGCCCACCCCGACCTCGCCGGTGGGCACCAGGCGCGGCATCTCGTGGTGGATCAGCTCCTGCGGCACCGCCGCGTACTGGTCGAGGAAGGCCTGGAGATGGCACAGCTGGGCCAGGCTGCCGTCCCCCGTCAGGGAGCCGGCCATGCCGGGCGTGAACACGAACACCGCGATGTTCGCGACGATCAGCGCATACGTCACCCAGGGGGTGCCGCGCACCGGGTTCACGTCATGAACGGGAATGACCAC

Protein sequences of DBSCAN-SWA_3

>NZ_CP010849|6129052:6153047|6150222_6151758_-|WP_044385025.1|DBSCAN-SWA
MSLDSITTSVDKAVSGFFEPIATWLVDVVFYSIPVGGTDLPLIVAWLVIAGLVFTGWFGFVQLRKFKLAVDVVRGKYDEKGSAGEVNHFQALTAAVSGTVGLGNIAGVAVAVSIGGPGATFWMILCGLLGMATKFVEVTLGVKYREVHADGTVSGGPMHYLPKGLAERFGKNGKTLGKVLAVLASFFVLFFGLFGGNLFQVNQSYAQLVSVTGGEDGLTGSSAGALFFGILVAALVGVVLLGGIRSIANVTSKLVPAMAGIYIAACLVVILVHVTSVPAGIVTIIEGAFNPQGVAGGVLGALIIGFKRAAFSNEAGLGSAPIAHSAVKTKHPASEGLVALLEPFIDTVVICTMTALTIVIANPASWAEARKGESIGGVTITSDAFATVMPWFPYILTIAVLLFAISTVLTWGYYGLKAWTHLFGRSRTSELVYKVVYTLFAIAGSLLTLQTLIDMADAVLFMLAVINIIGLYLLAPVVKRELNSFLEFVRARDAGDITEDDTDQESAKTTV
>NZ_CP010849|6129052:6153047|6131071_6131566_+|WP_029386827.1|DBSCAN-SWA
MRRRTVTAGNLEEILQLTTPAPQTEQEAVAPAAPPPPREEHGLRTEFEFELPRGYVDEAGVLHRDGAMRLATARDELRPQIDLRVKENPAYLSVVLLSQVITRIGTITDVHAGIVERMYATDVAFLQDFYRRVNSEGHTRAAVTCPHCEGGFEVDLSGGRLGES
>NZ_CP010849|6129052:6153047|6146639_6147788_-|WP_052808688.1|DBSCAN-SWA
MPRTTQPPPDDFAHSGEQAEIRELGDLLDRAAPDPGLFPADLLEARAGIEEVLRGQGDERSGAGAPERLTETTNIQGVGIGRARPTDTWACRETPAPGQWTLHVYLDQPRDAEDVASVLVERMGARAAGTSDVPVVPVTTGPIVTQKFVSRRRPAPGGISLVSVPNAEDLGTLGCLSTGRSAPRNQRTLIIGCNHVLANSNLGSLGDCVAQPATGDFGSCPADLVAVLERFARLEFGGPVNTVDCATAWAVPTDVSPRVLTPSPFGDLEIPISATTTAATVDMAVGKSGRTTEVTTGRVREVGASHWVVYPSGDKAFFSGSIVIQGDVGPFSLKGDSGAIVWTLDLIRQPVAMVFAGEMDGSRSYANPIDIVTQALDVFITA
>NZ_CP010849|6129052:6153047|6135607_6136330_+|WP_044385013.1|DBSCAN-SWA
MSPAVRSSRARAQLTLKEPPASVGAKPGGTIARLDLQFNPSTLELRKTTEWRRSPSRMAEESALPEFVGSGPRTLSLEVFLDATATHDNSVEQAVEKLMKACVPTPASLGRKKPASPWVRFEWGTARTTSFDGVLSSLSVTYTLFDVDGRPLRATCALTIEEASVDTPGQNPTSGARTARSTHTVVAGDSLALLAWREYGDATAWRVIAEANDIDDPMALAPGTELVVPGLRDEGAEEER
>NZ_CP010849|6129052:6153047|6142327_6143074_+|WP_044388545.1|DBSCAN-SWA
MAPRPTVRPVAVPDDVTGTPCPACGTPNPPGRRFCRRCAAVLNPEEKPPPLPWWRTVWPFRRRARASSGRAVRLLVILAVVAALCAGGLLLLPAGRALIEDTRDKLGKPKPITPVSVEASDEVPGHPARNTTDGLSNRYWGASAEGASVTYTFRRPFRLVDLLVTNGASASAQPYARQARALELELEVTTQDGTRHTRKLTLGDKPGPQPVPTGISDVKTVRLVLRSPTGLAPGRHLALAEVEFFQRS
>NZ_CP010849|6129052:6153047|6139041_6141000_+|WP_044385017.1|plate|DBSCAN-SWA
MALPSPNLDDRRFQELVDEAKRYVQQRAPEWTDHNVSDPGVTLIETFAYLVDQLLYRLNRVPDKNYTAFLDLLGIRLFPPAAASADVDFWLSAPQPDTVVLPAGTEVTTTRGETDDAVVFTTTGELHIVPSELTRLVTAPRAGEQTDRTRTLAEGRDIPCFQAAPEPGDALLFGLPTAVPRCIVAVRLDSRVEGVGVDPRQPPLVWEAWHGSGWQVCETGPDTTGGLNRPGEVIVYVPAGHRASVIGGTRAGWLRCRVTEPEPGQPFYSESPTVREASVFTVGGTMCAEHAVTVTDVPLGTSEGVAGQTFRVGRPPVLLDGAPPVVEVSSAEGWQRWDVVEHFGRSGPADRHVRVDATTGEFAFPPALREPDGTLRQCGAVPPKGAQVRVARYRTGGGPAGNVARGAISVLRSSVPYVARVTNREAARGGVAGETVANAKLRAPEALRMQERAVTAEDYEILSRQAAPSVRRVRCLPAADDPGAVRVLVVPDAVPDEGDRLRFEQLIPSDRVLQAITSCLDERRLIGTRLVVEPPVYQGVTVVVRLTAAPGDADRVREAALAALFGYLDPLRGGPEGTGWPFGRPVQYGEVFGVVQRATGDALVEEIRLFPADPITGRRGAPSDRIDVGAGALVFSYQHQVVVTAAGPEERG
>NZ_CP010849|6129052:6153047|6140996_6141560_+|WP_044385019.1|tail|DBSCAN-SWA
MSRAAVPGLPSRYPIGGQLPALYAEDDLAQRFTAGLDTVLAPVFSTLDNLPAYLDPRIAPADFLAWLASWVGAADDRAWPVEVRREAVVRAVELHRWRGTRRGLVEALGLALGAHAEVTGDGGARWSGTPGAELPPAPAAEVLVRVWPGREERIDPDRAREIVRAMCPVHTVCRVEILPGPPAGEGR
>NZ_CP010849|6129052:6153047|6131913_6134925_+|WP_044385011.1|DBSCAN-SWA
MPGAAASAPSVPGDWDGGWRRTTAPELTLSRAPLGVSDGLSFRAGLTAWQNPSFGTGLGHAVLPTAPAGVVRGVVGPATPRTIGTGGGPLLLGAPRGHGAGEPLPAAETRQAADGGDRRDPPPATPRGARQGGRASARPGPSFRPRPSPQPAPSGPAGSPGSTEPAGTSGPADALTGGPGGAPRSRGLLSTGSAGTLPSAPPAVQRAERPGGGPAPTADIPLVRRVAAVAPGPGRDEPVVQRAARRASDGPYAPQPQPQAQAQERTQTPARPGTPAAPRTRSTGSGPDPKRTPGTPSGSGGTPPGRAARSGGPERAGASRTSDASAASEEAAAGAGGSFPAARVRPLGGALTVARRPVGPVRRVRAVPPAMLPAPGDRADGGTAPSPAEAAAPATGPVQRTARSAEDRAPLGAPLNALPATALPATALPAADGPARPSASAARSATGDPAASGPALPVVQRHAQDGAGTPGPRDVGEERTAHGGPAARAGATDPAPGTGRGGARARGGLGAPLSALPPSAELPRSAASGRPAPRTGYGPDVQRAPARPDRGADTTSAPSRADGGRTEAPRTAPGAAPPPSAAADSPPGAAEQTPLLGTREVQRLAAPADEGAARPGAADPGQAPARPLVKPSPDGAARVSREANGAVAAAADPRGARPAPPGPGGQPPREPVVPVRPVSAARPAHGGAGGAAGAGGATVRTGAGTGAGAAPSPGAAGRGALTVSRAAVLPASPASPAPRTLPLLAARPLRTETRLAEGAAPPVASRPGGRPVVAARWTGAPAAVSDASRSGAAPSPAPVPGAPAPSASSGVRSAAVRPGPSAPGTGRAASDGSGRGVPVVRPAPHRGGAPGTTVQPATAPARSLPVAGARTPTPATGPAATVPPAPSASVPVVRPRAVPAGPGPATGGEKGPVAPVVQRKTAGTAQAAGGAPPARPRSAAPPSASGTTASGTAHRAGAPPDPGRDRDDLDDLARRLLDPVSRLLRAELRRGRERMGRPHDRRR
>NZ_CP010849|6129052:6153047|6135039_6135465_+|WP_029386810.1|tail|DBSCAN-SWA
MTDSIFATSVFFRLAIGGNDLGAFHTCSGMGAEVEMETYAEGGNNGFTWNLPGRVTWSNITLTRPVTADTAKIGRWLDETLRRVEPKDGEIVALKPDLSRIISWQVFGIVPVRWQGPSFDPASSQAAVETLEIAHEGLRPL
>NZ_CP010849|6129052:6153047|6143803_6145801_-|WP_063856829.1|DBSCAN-SWA
MSDHQALRETGRTGRDRAPARKAAVAPRERPAGLLALQAAAGNAAVVQRLRRAGHLDGRDQDPHGPGQGEQAARAVQRSTVHDVLRAPGRPLDEATRADMETRLGADFSDVRVHTDAAARASAAEIGARAYTSGNHVVLGAGGGDPHTLAHELTHVIQQRRGPVAGTDHGGGFRVSDPSDRFERDAEATARRALSGPSPAHGPSPAHGQETGAGRASGAPVQRAAAGGSGLPVIQRWTDGTMSGDDPVFQADNGRAGSVEVHNLHGRPLGAAANSPSVEPVGWAQLRQEGYTKMAPGGEKPVGAPYRAVRMHLFNGRLGGPGHNVLNLAPGPGKLNSQMSAQAEDPAKLLVELGHKVWLRTTVRYQDNNTNGANFASVVPNHITMEWGVEGDPASARQWSSSISLPVDPLSAAQVAVYSTYAGTAGQLVQEMGAANVSDQMRAQVLGLVPNDQLKLALLNNFPALYRGAEGADQARYIMLYPTAADRVAFLGRVGVTAQELFPQALQPLYRAGAQAAAAAEGVFRAWGLSDDEQRQMVFHYGEELLQAIGMAGVELIERLGDRGYALVKYYSEPDQVILLNTLESRGTLGALLQSANTPAVRNALLDHWAEYRGNATSDAKTSFIEASGISQAHKTAYRNWRNSQDRSIEYRDNRPRRAAAGANR
>NZ_CP010849|6129052:6153047|6143154_6143784_-|WP_052808687.1|DBSCAN-SWA
MTAGYRRRIAERVARLGATPGFSVRAYEVAPPVTDAELASVTASVQGRLPVGVAEFYGELNGFRLEWEYTAPEGGGSPTDFGSINVRPLADVFAEGLGDTWYDDFEGGDRFRAVKPFDVYAPEACAAFLQEPGGAPRDDVHFHYFGESLSPLNLTFPQYLEGALVSCGYVDWRMALTPDDPGLPAARRTLERMRAIIPGFDRLPQPGPA
>NZ_CP010849|6129052:6153047|6129052_6130600_+|WP_044385007.1|tail|DBSCAN-SWA
MPTYLTPGVYVEEVQSGARPIEGVGTAVAAFVGFAEAGPFHTPTLVTSWDQYTQQFGGFTEGTYLAHAVYGYFANGGGAAYVVRIGGSAEDSSAPAADGTGRGQQAGAPRPVELGGFLVAARPGATGVSVEIADAPGEEPPEDRFRFLVRQGGEVVETYEASTRKSVKGYLVSQARNSKLVEVTERRDAPQARPAAQTVALPDAPAAPGAVARLDPSEYVGDAAARTGFGGLETIDEITMVAVPDLMSAYQRGDIDAEGVRTVQLAVISHCEQMGDRVAVLDTPPGLTAQQVRTWRNDEAGYDSRYATLYYPWVRVFDPAAGRNTTVPPSGHVAGVWARSDAERGVHKAPANEVIRGAVDLEIRLSKGEQDLLNPIGVNCVRAFPGRGVRVWGARTLSSDPAWRYLNVRRLFNYLEESILLGTQWVVFEPNDDRLWSSIRRNVAAFLTEEWRRGALFGRTAEEAFYVKCDRDNNPQESIDQGRVVCEIGVAPVKPAEFVVFRLAQFSDSTSLIDE
>NZ_CP010849|6129052:6153047|6130634_6131075_+|WP_029386828.1|tail|DBSCAN-SWA
MAEGDALSTHVFGVQLGGYLVESIQEISGLTVEEEVVEVRQVSATGKQIIRKQPGARQAGEITITRGLDQSSEFTNWIKETLNKGAVNSARQNLTIEIKDSEGTTVRRIQLMQGWASKWEGPSLKAGESSAATETVTIVFEEIVVE
>NZ_CP010849|6129052:6153047|6152237_6153047_-|WP_044385027.1|protease|DBSCAN-SWA
MVIPVHDVNPVRGTPWVTYALIVANIAVFVFTPGMAGSLTGDGSLAQLCHLQAFLDQYAAVPQELIHHEMPRLVPTGEVGVGPQGAGCVIAPPGYDKSPELSVLTAMFLHGSWLHLLGNMLFLWIFGNNIEERMGHLRFLLFYGVCGYAASYGFALANSDSGDPLIGASGAIAGVLGAYLVLYPRARVWVLVPFLIFLPLRLPAWIVLGLWFVLQAFYSAGQGVSDAGTVAYVAHVVGFVAGLLLAWPLKPGTPPPPQPRGALFGRRAR
>NZ_CP010849|6129052:6153047|6138619_6139042_+|WP_029386814.1|DBSCAN-SWA
MSDRFIGRGWAFPMRVGPTGGIALVEREREIEEAIRLVLATAPGERPMRPEFGCGIHDYVFAPGDGATAGRVAQQVREALERWEPRIAVDDVVVAYDTVEAGTLYIDVHYTVRSTNDRRNLVFPFYTIPSDEGGGERGAA
>NZ_CP010849|6129052:6153047|6148621_6150073_+|WP_044385023.1|DBSCAN-SWA
MDGPQPTTRSGAVVATLALAGTVAAIMQTLVTPLIADMPQILNTTPSNAAWVVTVTLLVAGVCVPVSGRLGDLLGKRRMLLVCAVPLVVGSVVCALASSVVPMIIGRGLQGMGMGMVPLGIALLRDVVPQEKLSGSIALVSASMGIGGAIGLPLAAAVAQYADWRVLFWGAAVLALSVGTLIFFFVPDVPAGAKGQRFDAPGAVGLAIGLVSLLLAISKGGDWGWTSGTTLGLFALAVVSLAVWGFYELRTREPLVDLRTTARPRVLFTNASSILIGVGMYAFMLIAPQLLQFPEATGYGLGQSMLAAGLYLAPGGVMMMIVSPLGGKLINARGPKFTLICGALVIAVGYGIALPLMGTAWGLMLVGIVINSGVGLAYGAMPALIMSAVPVSETAAANGFNTLMRSLGTTIGSAVIGVVLAQMTITMGGHTLASEDGFRTGLLIGCGVAVVAAAVALLIPAVRTGTDDSAAAKAPAGQEPARA
>NZ_CP010849|6129052:6153047|6138302_6138623_+|WP_044388543.1|DBSCAN-SWA
MPAAARTGDPTSHGGLISTPPPAAAAVVARVLIGGRPAAVVGSLHACPMPPHAAMGPANVILPNPAALAAGTVLIGGVPAARMGDTTACGATVLAGAPNVQIGGGR
>NZ_CP010849|6129052:6153047|6147992_6148532_-|WP_078969350.1|DBSCAN-SWA
MSDAYDGKGELRGVAPQRRGHVNTADRATAQVEFEQMLLSRYMHLHKGKGRRADSVLDRSAYILLSRIRAQGPMSIGQLGDAFGLDASTLNRQTAAAMRAGLVERIPDPDGGMARKFRITEEGERRLDEERAGLVASLDRIMADWPEEDIAAFAGYLRRFNSDIERLHGMPWPRACVNP
>NZ_CP010849|6129052:6153047|6146094_6146571_+|WP_044385021.1|DBSCAN-SWA
MMSNRRPGGALAAGLIAAAATSAFSHPAQAAPEAAPKAPAQAPVTCYATSCHGLDPIETHCVDDAVTIDDATLDGRIVRLRYSAECRAAWAQLWFGKPDDRAYVRTEEDGHLVAVTSVTVRPWDGNSVYTPMVNDKDLKAKACLELPPDSDTACTIFY
>NZ_CP010849|6129052:6153047|6136326_6138150_+|WP_044385015.1|DBSCAN-SWA
MSTAEAQGGRSFAADPVVEAPAELPKIWAAQLVSCVVDENVGLPDAAVLTFRDPDHEFLRTTGITIGTPLRVSVVTVSGRARERLFNGEVTALEVDRDSTGSFTVVRAYSKAHRLQRGRKVVAYRNMTAAAIVRKVAAGAGLACGTVEAAPVSYRQLSQANVSDWEFLQYLAGESGAQVRVDDQGVLQFTRPEKAAKAPAPSTPATRDPMVLEYGRNLLALRAALSAADGAASVEVRGWDVTTKKPLVARQPSVVSDTVVPGLSPQAGARFGASAKLAVTDTPYRTQAETTAAAGAMAAQVSAGFGELEAVAEGNPRLRAGKPVALGNVGPAFSGRYTATAVRHVLEPYGGYRTTVWVSASPDRSLTGLVTGANAPGRGPRMPGLAIGVVTDVREPGGAERGEVRLRFPWLDDTYTTDWVRTVQWGGKGGGGVVSPEVNDEVLVGFEQGLLDSPYVIGGLYNGVDRPSPHDVPLIDATSGRVNRRSVVSRSGHRVELLDARAPGPSGLRLTTGDERLEVRLDDRRDRIELTVYAGRGRPLTSVLLDRDGITLDAGRGDVTVRGRRVEIDATETATVGGRSVRVTGQTEATVDGGLLGVLKARLIKIN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044385007.1|6129052_6130600_+|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	9.7e-69	34.9
WP_029386828.1|6130634_6131075_+|tail	phage tail protein	NA	NA	NA	NA
WP_029386827.1|6131071_6131566_+	hypothetical protein	NA	NA	NA	NA
WP_044385011.1|6131913_6134925_+	hypothetical protein	NA	NA	NA	NA
WP_029386810.1|6135039_6135465_+|tail	phage tail protein	A0A059XEM3	uncultured_phage	4.6e-05	28.3
WP_044385013.1|6135607_6136330_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_044385015.1|6136326_6138150_+	VgrG-related protein	NA	NA	NA	NA
WP_044388543.1|6138302_6138623_+	PAAR repeat-containing protein	NA	NA	NA	NA
WP_029386814.1|6138619_6139042_+	GPW/gp25 family protein	A0A1D8KT65	Synechococcus_phage	9.9e-08	32.3
WP_044385017.1|6139041_6141000_+|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_044385019.1|6140996_6141560_+|tail	phage tail protein	NA	NA	NA	NA
WP_044388545.1|6142327_6143074_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_052808687.1|6143154_6143784_-	hypothetical protein	NA	NA	NA	NA
WP_063856829.1|6143803_6145801_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_044385021.1|6146094_6146571_+	YjfA family protein	NA	NA	NA	NA
WP_052808688.1|6146639_6147788_-	hypothetical protein	NA	NA	NA	NA
WP_078969350.1|6147992_6148532_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_044385023.1|6148621_6150073_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	4.6e-12	26.0
WP_044385025.1|6150222_6151758_-	alanine:cation symporter family protein	NA	NA	NA	NA
WP_044385027.1|6152237_6153047_-|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP010849|6740493:6748843|DBSCAN-SWA
CATGGCCCGCCTGCAGATCCTCGAACTCCCCGAAGGTATCGGTGATGACCGGCCGCCGTTCGTACTCGTCGTAGACCAGATGCCGAACGACGAACCCGGCTTCGAAGCGCTCCGCCGCGACCTCAACGACGGGAACCTCGCCGAACGCATCGGTGCCCGCGCCGTCCTCGTCTTCGAAGACACCATCGATATCCCCGCCAACGACGTTCCCATCAACCCCGACTCCGAGCAGTTCCGTGCGCTGACCCAGGACGAGATCCGCAAGGCGCAGGCCGAACTGGCACAACACCTCAACCACGATGCCTGACGTGACGGTGAAGCTGTCCGACGGCGTCCGAGAGATCACCGTCGAGATCAACGGCAGCGACGACGACCCGCTCACCCGCGCCGAAGACGCCGCCATCCGGCTCTACAACGTCGTCACCAGCAGCCCGCCCGACCGGCGCGCCGGCTTCGGAGGATGGTCCGTCAACAGCGATACCGAACGCAGCGGAGAGGAGTAACGATGAGCGAACTCCGAGGCGCAGACATCGAGATCATCGAGCGTCGCATCAACCCGGGCGACCGGAGCGGGTTCCTCGTCCCTAACGCCGTCCGCATCAACGGAACCGAAGTCGCCATCCCCGAAGATGCGCGCATCCAGATCCACGAGATCACTCCTGAGGATGTCGTGACCGTCACCCTCACCATCTTCGCCAGCAGCGTCACCATCCGGACGGAGACCTCGCCATGAGCGGCGGCTGGAAGGGCAGCACGAGACGCCGACGCCTCCCCCCGAACTGGGCCAGCGAGATCCGGCCCGCCGCACACGCCCGCAACCCCGACCACATCTGCCACCTCTGCGGACAACCAGGCGGCGACTACCTAGACCACAAAACCCCCGGCGACGACCACAGCCTCGACAACCTCGACTGGGCCCACGACCGAGTCCCGCCCCACTGCCACCGATACAAGAGCAGCAGAGAGGGCAACTCCGCTCGGTCAGGACGACGACGACCACCCGAGTCGCACCCCGGGCTGAGGTGAGCAGTGGCCGCCTACCTCATAGTGCATCCCAGGGACCAGCAGAAGGACGACGTACACCTCGAAGACCCTGCCCTAACCCTTGCGTTCGAAGGCGGATGGGCTGTCTTTCGTGACGGTGAAGGCGTTTGCTTCGCCGTCCCGTGCGGGCAAGGAGCGTCCATCCAGCGGGTAGACGTAGAGCAGCCCGCGCCGCAAGAGGAGTGATCCGCTGTGGCAAGGAATAGGGGCGGCAGTGCTGCCACGCTGAAGCGGTACTGGGGCCAAGGGCGAGGCGCGGCAAAGATCCGCTGGAACACCCCAGGCGACTACACCAGGTGCACGAGGCAGCTGCACAAGTACCTCGGCGCCCGAGCGAAAGGGTACTGCGCTCGCCTGCACCGCGAACGAACCGGCATCTGGCCAGGCGACCGGCGCAATGTAGGCCGGCGCCGCTGAAGGACCATGCTGTCAGTGGCAGTTGAGAAGATAGAACCCCGGCGAGTGCTACCAACACTCCCGGGGCTACGGCCGATCTGACGGAAGCAGACCGACATGACTGAGGCTACACGCCCCGCCTTCATCAACTGCGCTCACTGCGGAGCCGAGAAGAAGGTCGGCCGCAGTGGGCCGCTACCTACCTACTGCTCAGCATCCTGTCGCGCCGCGCTCGGATATCAACGCAGCAGGAGCGACGGACGGTACGCAGCCGCCCTACTCGCTAAGCGGCAGGAGACTGCTGAGCGGCAGGCGGCGAGCGCGCGGTCGTGCCCGTACTGCGGTACAGCAATGACGCACCCAAGGCGCGTGCAGTGCGGGAGCACCGAGTGCCAGAGGCGCTACTGCGCCGACCGTATGCGCGAGTGGAACCAGGCATACAAGGAACGCACAGGCGAGTGGTATCACCGTCTCTACGCGGAACAGCAGCGGGCATACAGCAAGCGTCGCTACCAGGAGACACCGCACTGGAGGATCCGATACCCAGAGGCTGGCGCTCGCGTTGACGCACGCAGGCGAATGAGGATCGAGCTGGCCAACCAGGCGGAGCCCATCGTGCCGGCCGACGTGCATGCCAGGGACCGATGGACATGCCAGCTGTGCGGTGGACCCATTGACCCTGAGGTCGCATGGCCAGACCCGAAGAGCGCATCAGTGGACCACATCATTCCGCTCGCGCTCGGCGGAGCGCACAGCATAGCCAACGTGCAGAGCGCACATCTGGGCTGCAACAGCGGCAAGCGTGACCGACTCTTCCAGGCCGAGCCGATCAGACCCTGATGATCACCCGGGGAGGGCCCCGCCCCCCGGCGATCTTCAGCTATCGGGCCGTATTGCCGTTGTCCTTCTGTACGGGTCTGGGATTCTGGGAGGTGGTCTGAATGGCAGGCGCCGGGCCGGCTCCGAAGGACCCCTCCCGCCGGGCGCGCCGGAACAAGGAGGCGCAGCCGCAGACGATCCTCCGCTTCGAGCGGGCCGAGGCTCCCGAGCTGCCGGACTTCCGGATCGAGAAGGACGGCGAGCTGGTCGAGTTCGTCTGGCCGGAGCGCACGCGTGAGTGGTGGCAGATGTGGGTGGACTCCCCGCAGGCGGAGCACTTCGGCTCTACGGACTGGGACTTCCTGCTCGACACGGCGCTCATTCACGCGCGGTTCTGGCGGGGCGACATGTCGGTGGCGGCCGAGCTGCGCCTGAGGGTGGCCAAGCACGGAGCCACGATGGAGGACCGGGCCCGGCTGCGGATGGCTTTCGCCGAGGCTGACGATGCGGATGGCGGCAAGGGGTCGTCAGGCACGGAGACGGCGAAAGCCCGGTACGCGAAGCTGCGAGTGGTCAAGCCCGGCGAGGAGGGCAAGCCGTCTGGGGGGTGATCCGATGCCATGGCGCGGGCCTACCTATCCCGGCGAGGTGCCGACTCTCGGCTATCAGGTGCTGGGCTGGATCGCCGACCATTTGATCGTTCCGGATGGTCCGGCGGCTGGTGAGCCGCTGGAGTTCACCGACGAGCAGGCGATGTTCGTCCTGCAGCTGTACGCGATCGACCCTCACTTCGAGGGCCCGGCGATCGGGGGGCGCGCTCTGCGGAACGGCCGCAAGATCCGCCGAGCAGTCCTGTCCCGCCCGAAGGGCTGGGGGAAGTCACCCTTGGTGGCGGCCCTGTGTCTGGCTGAGGCACTGGCGGACGTCGTGCCGGACGGCTGGGACGCGAACGGTGAACCCGTGGGGCGCCCCTGGACCTCTCTGGGCTTCAAGGCGAAGGTGCAGATCGTTGCCGTGTCGGAGGACCAGACGGCGAACACCTGGGATCCGCTCCTGGAGATGGCGCGAGGCGGCCCGGTCCTTGACGCCTATGACATCGAGCCGATGGAGACGTTCGTCAACGTGCCCCGTGGGCGGATCGAGTTCGTGACGAGCTCGGGCACCAGTCGTGAGGGGTTCCGGCCGGTGTTCTCGGCGATGGACCAGACGGAGTCGTGGATCCCCTCCAACGGCGGTCGGAAGCTGGCTGCGACGATCCGTCGAAACCTGGGCAAGGTGAACGGCTGCTCTGTCGAGACGCCGAACGCCTTCATCCCGGGCGAGGAGTCCGTAGCGGAGAGGTCGTTCGAGGCGTGGAAGAAGCAGCAGGAAGGCAAGCTGAAGCTCGACGAGGGCCTCCTCTTCGACCACCGTGAGGCGCCGGCCGAGACGGACCCGGCCGACGAGAGGTCGCTCCTGGACGGGCTGGCGGCGGCCTACGGCGACTCGGCGGACCGCAACGGCGGCTGGGTGAACCTTCGCCGCCTGCTGGCGGAGTACTGGGACCCGGATACGGACCCGCAGGACGCCCGCCGCTACTACCTGAACCAGGTCACGCACGCCACGGACAGCTGGATCAGTCAGCCAGAGTGGGCGGCCATGGCGGCGCCGGAGAAGGTCGTCGCGGACCGGGACGAGATCGTGCTCGGCTTCGACGGTTCTCGTCGCCGGTCGCGTGGGGTGACAGATGCGACGGCGTTGGTCGGCTGCCGGGTCTCGGACGGGCATCTGTTCCTGCTGGGCTGCTGGGAGCAGCCGGACGGCCCTTTCGGTGTGGACTGGCAGGTGCCCACTGTCGAGGTGCTGGCCGCGGTGGAGGACGCCTTCCGCAACTACCGGGTGGTCGGGATGTACGCCGACCCGGCGAAGTGGGAGTCGCACATCGCCGGCTGGGAGGCGAAACACGGGCGTCGGCTGAGGGTGAAGTCGTCGATGCAGCATCCGATTGAGTGGTGGATGACGGGCGGTCGGGCGGTGCAGATTGTCCGCGCGCTGGAGAAGTTCCGGTCGTCGGTGGTGGACGGCGAGTTGACGCACGACGGGTCGAGCGTGCTGACGAGGCACATTCTCAATGCCCGGCGGCGGGAGTCGAGGTCGGGCATTCAGATCGCCAAGGAGCATCCGGAGTCCCCGCGCAAGATCGATGCTGCGGTGGCCGCCGTGCTGGCGTGGCAGTGCCGTGTGGACGCCGTGGCCAAGGGGCTCGGTAAGAAGAAGGCGCGAGCCGGGAGGGTGGTGGTGCTGCGATGACCGCGATCATCCCTGAGCTGCCGTTGTTGACGCTGTCGCCGGACGAGCTGGATCTGCTGGGGGCTCTGCGGACGGACCTGCTGGGCTGCCGGATGCGATTGGAGCTGCTGGACGCGTATTTCAACGGCGAGCAGCTGATCCGGGACCTGGGCATCTCGATTCCGCCGCAGTTGAAGGGCCTGCATACGGTGATCGGCTGGCCGCGGATCGGTGTGGAGGCCCTGGAGCAGCGCCTGGACCTGGAGGCGTTCCGGTGGGCGGACGGGGCCGACGCCAGCGATCTGGAGGAGATCGCCGAGGCGAACGACCTTTTCGACGAGGCGAGTCTGGCGCATCTGGACGCGCTGACGTATGGCCGCGAGTACGTGACTGTGGGCTCTGGCGAGGCGGATCTTCCGCTGATCACGTTCGAGTCGCCGCTGGACATGACGATCTCCTGGGACGCGCGGCTGCGGGTTGCGAAGGCGGCCTTGCGGCTGTCGGCGGAGGACGGGGCGCAGTTGGCGACGCTCTACCTGCCGGACCAGACCGTGTATGCGGTGCAAGCGGGCGCGGGCTGGGAGGTCTACGACCGGGACCTGCACAACCTGGGCGTCGTTCCGGTCGTCAGGATGGCGAACCGGCAGCGGACCGCGGACCGGGTGGGCCGCTCGGAGATCACGCCCGAGGTCATGTCGATCACGGATGCGGCGTGCCGCAGGCTGATGGGTATTGAGGTTGGGGCGGAGTTCTTCCAAGCGCCGCAGCGGTACATCCTGGGTGTGTCGGAGGGCGCCTTCCAGGACGCCGAGGGCAACGCGAAGTCGGCCTGGGAGACGTACATCGGCCGCGTGCTGGCGCTGGAGCGGGACGAGGACGGTCAGGTCCCGACCGTCGGGCAGTTCGCTGCTCATGACCCGTCCGGCCAAACGAAGATCATCGACCTGTACGCCCGGATCATGTCGTCGCAGATTTCGGTGCCGCCGCACATGCTGGGCTACACCAGCGACAATCCGGCGAGCGCGGACGCGATCCGCTCGGCCGAGGGCGCGCTGGTGAAGAAGGCGGAGCGGCGCATCAGGCGGTTCAGCGCGACGCACCGCGGCTACATGAGGCTGGCGCTGTGGTTCCGGGACGGTGAGCCGCCGGACAAGTCGCGCCGGATCGAGTGCGTGTGGCGGAACCCGGCGACGCCGACGATCGCCGCGCAGACGGATGCGGCGGTGAAGATGGCGCAGGCCGGGATCCTGCCCGCCGACGGGGACGTGGTGCTGGAGATGGCCGGCCTGTCGGAGGATCAGCGGCGCCGGGTGGCAGCTGAGCGGCGGAGGAGCGCGGGCGCGGCGGCGAGCGGCCAGCTGATGGAGCGGCTGGCGCAGCTCGGTGACCAGTCGGCGCCGCTGCCGCCGGCCGCGGAGGTGACCGGTGGCGGCGGCGGTCTCTGACCGCGGGGAGGCGGCCGGCCGGTACCGGGCAGCTCAGGTCGGCCTGTCGCGCCTGCTGGTGCGGGATGTGCGCGGCCTGCGCCGGCTGATCCTTCCGCAGCGGCTGCGGGAGTCGGTGCCGGACTGGCTGGCGGCGATGAACGCGGTCGTCCAGCAGTACGCGCGCACGTCGGCCACGCTGGCGGCCGAGTTCTACGACGCGCAGCGGACCGCGGCCGGCGTGGTGGGGGCGCCGTTCACGGTGCCGCTCGCCGATCCGCCGCCGCGCGAGCAGGTGGACGAGTCGCTGCGGTGGGCGACGAAGGATCTGTGGCCGCGGCCGGCTGAGGAGGCCACTCCGGCGCAGCTGCAGCCGATGGAAGTCCGCCTGGTACAGGCGGAGAAGAAGGCGCAGGGCGTCGCGCAGAAGCTCGTCACCGACACTGGGCGGAGCACCGTGCAGGGTGCGGTGCGGCAGGACCGGCAGGCCACCGCGTGGGCCCGGGCGGCTGCGCTCGGCGCGTGCGCGTTCTGCAAGCTCCTCGCCTCCCGCGGCGCGGTGTACAAGCAGGACACGGCCGACTTCCGGGCGCACGACAACTGCCACTGCGGCGTGATCCCGGTGTTCAAGGGGCAGCGGTTCGAGCTGTCTCCGCAGGCCCGCGAGTGGGAGCGGATCTACCGCGAGTACGCGGCGCCCTACCCGGAGGACCAGCTCAGGCGGTTCCGCCTGGCGCTCGCCGAGCACGACAGCAACCCGCTGCCGGGCTCGAACTGACCGACCAACCCTACCGGCCGTCCTGGTGGCGGCCTTCTCAGCCCCTGGAGGGCGACTCACCATGCCCGAGAACGAGGAGACGACCGAGCAGGTCGCGACGGAGACGCAGCAGCCGGAGGCCGCCCCGGAGGCGGAGCAGGCGACGACGGACCCGTGGGCCGATCCCGACGCCGCGCGCAAGGAGATCGAGAAGCTGCGCCGGGAGGCGGCCAAGTACCGCACGAAGGCCGGCGAACTCGAGCCACTCGCCCGGAAGGCGCGGGAGCTGGAAGACGCGCAGAAGACCGAGCAGGAGCGGCTCGCCGAGCAGCTCCGCGCGGCTCAGGAGAAGGCCCAGGCGGTGCAGCAGCGCGCGGTGCGCGCGGAGGTGCGGGCCCTGGCAGCGGCCGAGTTCGCCGATCCGGACGACGCGCACGCCTTTCTCGACCTGACCGCCTACGTCGACGGCGAAGGCGACATCGACACGGTGGCGATCCAGCGGGACCTGAAGGATCTGCTGAAGCGGAAGCCGCACCTGGGCAAGCCGGCCGACAACTCGCCTCGTTCGCCCCGCCCGGACCGCACGCAGGGCTCCTCGGGCAACGGCAACCGTTCATCTTCCGATCCCGGCGTGATCTTCGCGGGGATCATGGACCAGGCCCTGAAGGGCCGCTGAGAGGAAGCCCTCCATGGCAACCAACCCGATCAAGCTGTCGGACGTCGACGCGACGTTCCTCCCGCCCCAGCTCACGGGGCCCATCTTCGAGAAGTCGGTCGAGCAGTCCGCGGTCATGTCGCTGGCCCGCCGGGTGCCGCTCTCCATGAGCGCCAACACGGCCGTGCCGGTGCCTCTGGACGTGCCGACCGCGGACTGGGTCGAGCAGGCCGGCCGTAAGCCGCTGGGCACGGGCGGCGTCGACATCAAGCAGATGACCGGCAAGAAGATCGCCGTTCTCATCCCGGTCGCGATGGAGGTCGTGCAGTCCAACGCTGCCGGTCTGTGGACGCAGCTGCAGAACGACCTGCCCACCGCGTTCTCCCGGGCGTTCGACCGGGCGGCGATCCACGGCCGCACGATGAAGGGCGCGGTCGGCCCCTTCCCGGACTACCTCGCCCAGACGACGAAGTCCGTCTCGCTGGGCACGACCACGCAGGCGAATGGCGGCATCTGGGGCGACTTCGTCACCGGCATGGGTGAGATCGTCGACGACGACTGGGACTACACCGGCACGGTCGCCGACCACCGCCTGAAGACGCGTCTGCTCGGGGCGACGGACACGACGGGACGGCCGATCCTCGTCGACACCACCCAGCCGGGCACTGGTGCGGCGCTGGCGGGCACCCTGGTGGGCGAGCCGATCGCCTACTCCCGCTCGGTGTCCGGGAAGCTGCGCCGCCAGTCGGGCACCGTGGACTCGGGTCTGCGGGCGATCGGCGGCGACTGGTCGCAGACCGCCTACGGCGTCGGCATGGACATCACCGTGCGGATCTCCAAGGAGGCCACCTACATCGACGAGGAGGGCGGTGTCCACTCCGCGTTCCAGGAGAACCTGGTGCTGCTCCTCGCGGAGGCGTACTACGGCTTCGTGCTGGGCGACGCTGAGGCATTCGTCAAGTTCACCGGCACGCCGTCGGGGTCCTGA

Protein sequences of DBSCAN-SWA_4

>NZ_CP010849|6740493:6748843|6747889_6748843_+|WP_044385875.1|capsid|DBSCAN-SWA
MATNPIKLSDVDATFLPPQLTGPIFEKSVEQSAVMSLARRVPLSMSANTAVPVPLDVPTADWVEQAGRKPLGTGGVDIKQMTGKKIAVLIPVAMEVVQSNAAGLWTQLQNDLPTAFSRAFDRAAIHGRTMKGAVGPFPDYLAQTTKSVSLGTTTQANGGIWGDFVTGMGEIVDDDWDYTGTVADHRLKTRLLGATDTTGRPILVDTTQPGTGAALAGTLVGEPIAYSRSVSGKLRRQSGTVDSGLRAIGGDWSQTAYGVGMDITVRISKEATYIDEEGGVHSAFQENLVLLLAEAYYGFVLGDAEAFVKFTGTPSGS
>NZ_CP010849|6740493:6748843|6742873_6743362_+|WP_044385865.1|DBSCAN-SWA
MAGAGPAPKDPSRRARRNKEAQPQTILRFERAEAPELPDFRIEKDGELVEFVWPERTREWWQMWVDSPQAEHFGSTDWDFLLDTALIHARFWRGDMSVAAELRLRVAKHGATMEDRARLRMAFAEADDADGGKGSSGTETAKARYAKLRVVKPGEEGKPSGG
>NZ_CP010849|6740493:6748843|6740997_6741225_+|WP_044385859.1|DBSCAN-SWA
MSELRGADIEIIERRINPGDRSGFLVPNAVRINGTEVAIPEDARIQIHEITPEDVVTVTLTIFASSVTIRTETSP
>NZ_CP010849|6740493:6748843|6747282_6747876_+|WP_044385873.1|DBSCAN-SWA
MPENEETTEQVATETQQPEAAPEAEQATTDPWADPDAARKEIEKLRREAAKYRTKAGELEPLARKARELEDAQKTEQERLAEQLRAAQEKAQAVQQRAVRAEVRALAAAEFADPDDAHAFLDLTAYVDGEGDIDTVAIQRDLKDLLKRKPHLGKPADNSPRSPRPDRTQGSSGNGNRSSSDPGVIFAGIMDQALKGR
>NZ_CP010849|6740493:6748843|6740800_6740995_+|WP_044385857.1|DBSCAN-SWA
MTVKLSDGVREITVEINGSDDDPLTRAEDAAIRLYNVVTSSPPDRRAGFGGWSVNSDTERSGEE
>NZ_CP010849|6740493:6748843|6743366_6745040_+|WP_044385867.1|terminase|DBSCAN-SWA
MPWRGPTYPGEVPTLGYQVLGWIADHLIVPDGPAAGEPLEFTDEQAMFVLQLYAIDPHFEGPAIGGRALRNGRKIRRAVLSRPKGWGKSPLVAALCLAEALADVVPDGWDANGEPVGRPWTSLGFKAKVQIVAVSEDQTANTWDPLLEMARGGPVLDAYDIEPMETFVNVPRGRIEFVTSSGTSREGFRPVFSAMDQTESWIPSNGGRKLAATIRRNLGKVNGCSVETPNAFIPGEESVAERSFEAWKKQQEGKLKLDEGLLFDHREAPAETDPADERSLLDGLAAAYGDSADRNGGWVNLRRLLAEYWDPDTDPQDARRYYLNQVTHATDSWISQPEWAAMAAPEKVVADRDEIVLGFDGSRRRSRGVTDATALVGCRVSDGHLFLLGCWEQPDGPFGVDWQVPTVEVLAAVEDAFRNYRVVGMYADPAKWESHIAGWEAKHGRRLRVKSSMQHPIEWWMTGGRAVQIVRALEKFRSSVVDGELTHDGSSVLTRHILNARRRESRSGIQIAKEHPESPRKIDAAVAAVLAWQCRVDAVAKGLGKKKARAGRVVVLR
>NZ_CP010849|6740493:6748843|6740493_6740799_+|WP_052808715.1|DBSCAN-SWA
MARLQILELPEGIGDDRPPFVLVVDQMPNDEPGFEALRRDLNDGNLAERIGARAVLVFEDTIDIPANDVPINPDSEQFRALTQDEIRKAQAELAQHLNHDA
>NZ_CP010849|6740493:6748843|6742511_6742772_+|WP_044388698.1|DBSCAN-SWA
MRIELANQAEPIVPADVHARDRWTCQLCGGPIDPEVAWPDPKSASVDHIIPLALGGAHSIANVQSAHLGCNSGKRDRLFQAEPIRP
>NZ_CP010849|6740493:6748843|6745036_6746464_+|WP_044385869.1|portal|DBSCAN-SWA
MTAIIPELPLLTLSPDELDLLGALRTDLLGCRMRLELLDAYFNGEQLIRDLGISIPPQLKGLHTVIGWPRIGVEALEQRLDLEAFRWADGADASDLEEIAEANDLFDEASLAHLDALTYGREYVTVGSGEADLPLITFESPLDMTISWDARLRVAKAALRLSAEDGAQLATLYLPDQTVYAVQAGAGWEVYDRDLHNLGVVPVVRMANRQRTADRVGRSEITPEVMSITDAACRRLMGIEVGAEFFQAPQRYILGVSEGAFQDAEGNAKSAWETYIGRVLALERDEDGQVPTVGQFAAHDPSGQTKIIDLYARIMSSQISVPPHMLGYTSDNPASADAIRSAEGALVKKAERRIRRFSATHRGYMRLALWFRDGEPPDKSRRIECVWRNPATPTIAAQTDAAVKMAQAGILPADGDVVLEMAGLSEDQRRRVAAERRRSAGAAASGQLMERLAQLGDQSAPLPPAAEVTGGGGGL
>NZ_CP010849|6740493:6748843|6746444_6747221_+|WP_044385871.1|DBSCAN-SWA
MAAAVSDRGEAAGRYRAAQVGLSRLLVRDVRGLRRLILPQRLRESVPDWLAAMNAVVQQYARTSATLAAEFYDAQRTAAGVVGAPFTVPLADPPPREQVDESLRWATKDLWPRPAEEATPAQLQPMEVRLVQAEKKAQGVAQKLVTDTGRSTVQGAVRQDRQATAWARAAALGACAFCKLLASRGAVYKQDTADFRAHDNCHCGVIPVFKGQRFELSPQAREWERIYREYAAPYPEDQLRRFRLALAEHDSNPLPGSN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052808715.1|6740493_6740799_+	hypothetical protein	Q6VY58	Streptomyces_phage	5.3e-11	41.0
WP_044385857.1|6740800_6740995_+	hypothetical protein	NA	NA	NA	NA
WP_044385859.1|6740997_6741225_+	hypothetical protein	NA	NA	NA	NA
WP_044388698.1|6742511_6742772_+	HNH endonuclease	A0A1L6BZD8	Pasteurella_phage	2.5e-14	53.6
WP_044385865.1|6742873_6743362_+	hypothetical protein	Q6VY56	Streptomyces_phage	2.9e-59	70.9
WP_044385867.1|6743366_6745040_+|terminase	terminase	A0A0K1Y5V8	Streptomyces_phage	2.4e-190	59.4
WP_044385869.1|6745036_6746464_+|portal	phage portal protein	A0A2H4JAT8	uncultured_Caudovirales_phage	5.1e-72	40.7
WP_044385871.1|6746444_6747221_+	hypothetical protein	G1BSM8	Mycobacterium_virus	6.7e-10	27.0
WP_044385873.1|6747282_6747876_+	hypothetical protein	NA	NA	NA	NA
WP_044385875.1|6747889_6748843_+|capsid	phage major capsid protein	V5R986	Arthrobacter_phage	4.9e-39	35.6

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NZ_CP010849|6753001:6763672|DBSCAN-SWA
CGTGGCCGCGATCAGCGTGGGGTCCGTCGAGGTCGATGTTGTCCCGAATGCGCGGGGGATCCGCCGGCGTCTGCAGGAGCAGGTGGTGCCCGCCGCCGACTCGGTGGGCGACGAGATCGGCCGCGTGATCGGCCGGCACGTCAGCACGCAGGTGGCGCAGGCGGTGCGCACGGGCGTAACGACCGGGTCCCGTACAGCAGTGCCGCCCGCTACGCGCGGCGGCGAGCAGACCGGCTCCGCCTTCGCCCGCGGCATGCGGACTCGCGTCGAGGCGGCGCTGCGCAGCCTGCCCGAGGTGGAGCTGACCGCGGACTCCTCGGCGGTGGACCGGGAGATCCACCAGATCCGCGCCCAGCTGGAGACGCTGCGAGACGTGGAGATCGGCGTCGACATCGACGCCGGTGAGGCGATGGCCCGCATCACCCAGCTGCAGTCGCGTCTGGCCGCGCTCGCCGCGTCCGACGCCGACGTCGACGTGCGGATCGACACCGGCGCCGCGGCGGCCGAGCTCGCAGCGGTGCAGGCGCAGGTGAACCGCCTGGATGGCGACGACGTGACCATCGACGTCGACACGCGGTCCGCTACGGCCAACCTGTCGATGCTGACGACGGCCGCGCTCGCGTTCGGTCCGGCTCTCCTGCCGGTGCTGCCAGTGGCGGCGGCCGGCCTGGGGGCGATGGCGGCTGCCGCCTCGGCGGCGGCCGTGGGGGTCGGCGCGCTGGCCGCTGTCGCCGTCCCCGCGTTCGTGCAGATGGGCAAGGTGCTGCAGGCGCAGAAGGCGGCCCAGGATGCGGCTACGACCGCGACTCTCAAGGGCGGGCAAGCCGCGGCGCAGGCGGCCTCCCGGTCTCTGCAGATGGCGTCCGCGCAGCAGGCCCTGGCCAGTGCCCACCGCAACGCGGCCCAGCAGATCCGGCAGGCGGAGCAGGGAGTCGCGGACGCGGTGCGGTCGGCGGCGGAGGCGAACCGGCGCGCAAAGGAGCAGCTCGCGGGAGCGGTGCAGCAGGCTGCGGACCGGCAACGACGGGCGGCCGAGCAGGTGCGGCAGGCCGAAGAGCAGCTCGCGGATGCGCAGCGCGTCGCGCAGCGGGCGCAGGAGGATCTGACCCAGGCTCGCCGTGACGCCGCCGCGGAGTTGGCTGAGCTTGGGGACCGGGTGGCGAACGCCCGGCTGTCGGAGCGGGATGCCGCTCTGTCGGTGCAGGAGGCGGAGGTCCGGCTGCGCGCGACGCAGGCGGAGGGCTCGAAGGCCACCCTGCTGGAGCGGGCGCGCGCGCAGCTCGCCTACGACCAGGCGGTTCAGCGTCTGCGGGAGTCCCAGGCCGAGACGAAGGCGCTGACCGCGGAGAAGTCGGCCGCGGACAAGGCCGGCGTGGAGGGATCGGAGACGGTCCGCACCGCGCAGGAACGGCTCCGGGAGGCCGAGAAGGGGGTCGCGCGGCAGCAGCGTGCGCTCGCGAAGGAGCGGGCGGACGCGGCGCGTCAGCAGATCGAGAGCCAAGAGGCTGTCGCCGAGGCGCAGCGGAACGTGGCCCGCACCCAGGAGGAGGGTGCGCAGTCGGTGGCCCGCGCGCAGGAGCAGCTCGCTTCGGCTCAGCAGTCGGCAGCCGATTCGATCGCGTCGGCGCAGCGGCAGATCGAGCAGGCATCGTTGTCGGCGGCCGGCGGCGTGGACCAGGCGGCGATTGCGCAGGCCAAGTACGAGGAAGAGCTGGCGAAGCTGACGCCCGCGGCCCGGGAGACGTTCGACGCGTTCCTCAACCTGCGGGACGCGTTCTCGCAGTGGTCGCGGTCGCTGCAGCCGGCCGTGATGCCGATTTTCACCCGCGCGCTGATCGGCCTGAAGAACGCCCTGCCGGGCTTGACGCCGTTCGTGCTGGAGGCGGCGGGCGCGATCGAGACGCTGATGGACAAGGCGTCGGCGGAGCTGAAGCGGCCGTTCTGGGCTGATTTCCGGTCCGATCTGCAGGGCTCGGTGAGGCCCGCGATCGAGGGTCTGGGTGTCTCGTTCGGGAACGTGTTCAAGGGTATGGCCGGGGTGATCTCTGCCTTCCTGCCGAAGGTGGACTCGGTGTCCGCGCGGATGCAGACACTCACCGGCCGGTTCGCCGCGTGGGGGCAGGGCCTGAAGGGCTCCCCGGAGTTCGAGCGGTTCCTCGGCTACTCCGCCGAGATGGCCCCGAGAATCTGGGAGGCGCTGCAGCGGATCTCAGGGGCTCTGCTGTCGATCGGCGTCGCCATGTCGCCGATCAGCAGCGTCGTCCTGACCGTGATCGGCGGCATCGCCCAGGGTGTCCAGTGGATCGCGGACAACGCGCCGTGGGCGGTGCAGGCGATCTACGGCATCGTGGTCGCGATGGGCGCTTGGCGCCTGGCGACGTTGCTGTGGACGGGCGTCACGTGGCTGGCGACGGCTGCCATGGCGGCTTTCAACCTGGCCATGAGGCTGAGTCCGTTGGGCTGGATTGTCCTGGGGATCACGGCGGTTGTCACCGCGATCTACCTGCTGTGGACGAAGTGCGATTGGTTCCGGAGCGCCGTCACGGTCATCTGGGAGGCCATCAAGATGGCCCTGGGCGCGGCATGGGATTGGATCAAGTCGAACGTCCTGGAGCCCATCGGGACGTTCTTCACCCGGATCGTGCCTAGCTGGGCTGAGACCCTGCGGGACAAAGTCCGTGTCGCCTGGGACGTCATGAAGGCGGCCCTCGCCCTCATCTGGGACTGGATCAAGCAGCATGTGCTGTACCCGATCCGGGACTTCTTCATCAAGACGATGCCGGGCTGGGCGGCCACGTTGCGGGGCCGGATCGTCGGCGTGTGGGACGGCATCCGCGCCGGGATCTCCGGTGCGTGGGACCTGATCAAGAAGTGGACCATCTATCCGATCCGGGACTTCTTCACGAAGACGATGCCGGGCTGGGCCACGAGCCTGAGGGACCGTTTCATCGGGGCCTTCGATGCGGCCCGCAAGGGCATCAAGGCAGCCTGGGACCGCATCAAGGGGATCGCCCGGGAGCCTGTGCAGTACGTCGTGGATGTGGTGTACAACCGGGGCGTCCGTGGCGTCTGGAACGCCGTAGCCAGCGCCTTCGGCGCCCCCAAGCTGGATGTCTTCAAGTTCGCCTCCGGTGGCGTCATGCCCGGCTACACCCCGGGCCGCGATGTGCACCGCTTCGTCTCCCCGACGGGCGGGGCGTTGGAGCTGTCCGGTGGCGAGGCCATCATGCGGCCCGAGTTCACGCGGGCCGTGGGCTCTGGGTTCGTGCACACCCTCAACGCGGTCGCCCGGTCCCGGGGCGCCCAGGGCGTCAAGGCGGCCTTGGCCCCGATGCTCGGCGGTAACCCGCGCACACCCACGGATACGTCCCTTCGGTACAGCACCGGCGGCATCTACCCGGTGCAGCGGTTCGCCAGCGGCGGGATCTTCGACTGGATCAAGTCCGCCGGGTCCGCTGCCCTCGGCGCCGGATCGGCAGCCTGGAACAAGATCAAGGAAGGGGCGTCATGGCTCACTGACACCCTGGAGGCGTCCGCGCGCGCGGGTGTGAAGAACGTCGTCGACCCGCTGCTCGCCTCGTTCCCCGGCATGGACACCGGCTTCGGGAAGATGATCCGCCGCATCCCGAGTCGGATCGTCGACGCCCTGTTCGGATACAGCAAGGAGGCGGACAAGCGGGGCGCCGGCGGCATCGGGGGCCCGCGCATCCAGAAGGCGCTGGCCTGGGCGCGCACCCAGAACGGCAAGCCCTACCAGTGGGGCGGCAACGGAAACCCGTCGTGGGACTGCTCCGGTTTCATGTCCGCGATCGAGTCCGTCATCCGCGGTCAGAAGCCGCACCGGCGCTGGGCGACGATGGCGTTCTCGGGCCGGACCGCCCCTCCCGGATGGAAGCTCCGCCAGAAGTCTCCGTTCATGATCGGCATCACGAACGCCGGGGTCGGCCACACCGCGGGCACCCTCGGCGGCGTCAACGTGGAGAGTCGCGGTGGGGACGGGGTGGTCGTCGGGCGGCGAGCCCGCGGCTACAACGATCGCCTGTTCACCGACTGGTACGGCTTCAAGCCGGGCAGCTACGACTCGGGCGGCTACCTGCAGCCGGGCTTCAACCTCGCGTACAACGGCACGGGTCGGCCGGAGCCCGTGTTCACGACGGCGCAGGCCAACGCGCTCACCTCGCTGGCGGCGCGTGGCGGCTCGTCCGGACCGACCACGCTCGAGGGCAGCCTCTACCTCGACTCGGGCGAGTTTCTCGGCCGGGTCCGCGGCGAGGCGCAGCAGGTCATGCAGCAGGGGCAGCGAGAGCTTATCTCCGTCATCAACGCGAGCTGAGGAGGTCACCTTGGCGATCCCCGGGAACTTCCTCTCCCCGACGACGGAGTCCATCGACCCGAACACGTCGGGCTGGGCACCGAAGTCGAACTGCACCCTCGCGAAGGGGGTGGGCGGCCGGAACGGAGACGGCTGCCTCGTCGTCAAGAGCGTGGCGTCCGGGGAGACGCAGGCCCGCACCGTCTCCTCCTACCCGATCACGCCCGGCACCGTGTACTACTGCTTCGCGGACGCGGCCGGGTCGGTGCCGGAGCGGATCGGGATCCGGTGGCTGACTGCGGCGGGCGCCGAGATCAGCGTGACGTGGTCGCTGACCACGATGGCGGCCTCGGCCAACTGGCACCGGGTCTCCGCGGCCGGCCCGGCGCCGGTGAACGCGGCCACTGCCCAGGTGCTGCTGTCGTCCACGGAGACCGCCGCCGGGGTCAACCACTACTGGGAGAACGTCTACCTCGGGTTGCCGATCAGGATCCTCGGCAACCTGTTCGACTTCAACACCGAGTCGGCTGAGATCGACTTGAGCGGCTGGGCAGCCGGGGCCAACGCCACGATCTCCCGGCAGGCGCCGACAATGGGTTGGACCGTCACCAACTACACCGCGGGCGGCCAAGTGCTGGCCGTCACCGCGTCCGCCGCAGGCACCGCGAGCGCGATGACCGTGAACCGCCCCGCGGTCACGCCGGGCACCGAGTACATCGCCTACGCCTACCTGCAACCCCCGACGACGTCCTCCACGGCCTGGATCGAGCTCCGCTTCTACGACTCTACCGGCGCCCAGGTGGGTGTCCAGAGGAGCACGCTTGCCCCGCCGGGCACGGGCATGTACCGGCAGCGGGCGAGCATGGTCGCGCCCGCGGCGGCGGCCACCTGCGCGGTGGCCGCGGGCCTGGACGGGGCGACTGCGGGGCAGGTGCTGCGGCTGGAGACGGTGGCCGTCACCGTGGCGCCGAAGCTGATGACGGGCAGCGTGCTGCCCTACGCAGACAGCTCCTTCGAGCAGGGCGTGGCCGATTGGGCGACGGCTGCTGGGGTAGCGACGCTCGCCCGCACCACCCCGTGGGGCAGCTCCTCCTACGAGGGCGCCTACGCCCTGGCGGTCACCTCGTCGACGGCGACCACGTCGACGGTGCGGTCGGCCCGGTGGCCGGTCACGCCCAACGTGAACTGGCGTGCGCAGGCGATCATGCGCACGGCGGGAGGCACGTGGGCGAGCGTGACCGTCCGGGTGCGGTGGTACGACGCCGGCGGCGCCGACCTCGGCGCCTCGACCGGTGTCGGGTATGTGCTGGCGGGCACCGGCTGGTACGCGTGCGCCGCGGATGCGGTCGCCCCTGAGGCCGCGGCGCAGGCTGCCGTCGAGCTGATGCCCGCGGCATCGGTGGCCGGCAGCGTCCTGCATGTGGACGCCGTCACCCTGTGGCAGGTGCTGCCGCAGACCGCGGTGGAGGCCCGCCCCGACGACGGGTATGTGCTGCTGACGCTGCGGGAGCTCCCGCTCGACTACCTGATCACCGTGTACCGGGTGACGCCGGACGGCAAGCGGGCCGCGGTCCGCGGGGCGGCCGGGCTGATCGTGCAGCAGGTCATCACCTCGGACGTGATGCTCATCGAGGACCACGAGGCGCCGCTCGGGCAGCCGGTGAACTACCGCATCGAGGTGTACACGACGGCCGGCGCTGTCGCCTTCACCCGGTCGTCGGAGCCGGTGACGCTGGCGCTCGACGACATCAACACGGCGTGGATCAAAGACCCGGGCAATCCGCAGCGGAACTGCCTGGTCATGGTGGAGCGGGCCCCTGATTGGCAGCGGCCCATCGAGCAGGCGGTGTACGTCGTCCGCGGGCGCCGCAACAAGGTCATCCTGTCCGGCCGCCGGCAGGGCCTGGAGGGCGACCTCGCCATCTGGACCCGGTCCGACGCCGAGCGGGAGGCTCTGCACCTGTTGCTCGACTCCGGAAACGTCCTGCTATGGCAGGCCGCGTCGGGCATGGGCGTCGCCGACATGTACGTCGCCGTCGGCGAGGTCACCGAGGCGCGCGTGAGCCCGCTCGCCCAGGAGGAGTGGCGGGCCTGGTCGCTACCGCTCGTCGAGCAGGACATGCCGGTCACCACCGGCGTGAACGGGGCGCGCGGCCGGACCTGGCAGGACGTCGTCACCGAGTTCGCGACGGCCGCCGACCTGCTGGAGGTCTACGCGACCAGCGAGGCGCTGCTGCTCGACCGCCGAACGGGGTGACGCCGTGTACCCCGTCAGCGATCGATTCCTGACCCGGCTCGCGGAGAGCCACCGGGTCGCGACCCAGGTGCAGCTGTTCCTGACGACGGGCGAGGTCGTCGAGCTCGAGCACACCGGCGGCTCGGTGACGGTGGACCGGGGGCAGGCGATCCGCCGCACCTGCACCGTCACCGTCGCCGACCCGTCCCTGATCCCGCGCACCCCGACCGACCAACTCGCGACCTACGGGGCTCGGCTGCGGATCTCGCGCGGCGTCGAGTACGGCGACGGGACGAGCGAGCTGGTGCCGCTCGGCGTGTTCCGGCTCGACAGCGTCGACGGCGACGTCGCCGAGGGCCCGGTATCGCTGCAGGGGAAAGACCTGTCGGCGATCGTCGCCGACGACAAGCTCACGGCCCCGTACTCCGCCAGCGGCACCGTCGTGGGCGCGGTCACCGCACTCATCCAGCGGTCGATCCCGGACGCCGACATCATCAGCCTGATCGACGACGCCCCGATCGGGCGCCGCACGTTCGACATCGAGGCCGATCCCTGGGCTGGTGCGCAGGAGATCGCCGCGGCGGCCGGCGCCGAGGTGTACTGCAATGCGGACGGCGTCTTCACCATCGGTCGGCTGCCGGACCTGCTCACGGCCGAGCCGGTGTGGGCGGTGGAGGCCACTGAAGGCGGCGTCTACATCAAGGCCAACCGGGCGATGTCCTCGGACAAGGTCTTCAACGGCGTGCTCGCCCGCGGCGAGAACACGAGCGAGAACACCCCGCCCGTCTCCTATCTGGCCGTCGATAACGACCCGGGCAGTCCCACGTACTGGGGAGGACCCTTCGGGCGACGCCCCAAGTTCATCTCCTCCAGCGCCTACACCACCACCAACGCGTGCGCGCAAGCAGCGAACCTGGAGCTTGCCAAGGGCAGAGCCCCCAACGCTTCGGGCGACATCTCGTCGCTGCCCAACTCGGCGCTCGAGCCGGGCGACATCATCCGCGTCATGCACCCCGACGGCGCCCGGGAACTCCACCAGGCCGCAGCCTTCACGGTCCCGCTCGACGAGGGGAGCGACTTCCCCATCAGCACCGTCTCAGCGAAGGAGGACGCGTGACCGCGCTGCCGAACCGACCCGCGCCCGCCGTGCACCGCGACCTCGCCTGGGCGCTCAAACAGCAGGCCACCCGCGCGGGGGAGGGAGCCCCCTCGGTGCGCGGCTCGGACTGGCGGCTTGCCACCGTGACCGCCGTCAACGCCGACGGCACCGTCGCGGTGGACGGCATCCCTGCGGTCCGATGCATGCCCACCTACACGCTGCCCGCCATCGACGACGTCATCGTCATCGACCAATCCAGCAGCGGCAACTGGCTCGCCTGGGGGCGCACGGCCACGACCGCGCAGACGTGGACGACGCTGGCGCTCGCCAGCGGGTTCCAGAACCCGGGCCACGGCCACACGCCCGCTTACCTACGGGAGGGGCGCCGCATCTGGCTCCGGGGGCGCATCGGGCCGACGTCCGGCTCGATCGCCGACGGCGCGACGCTGCTGACGCTGCCGGCCGCGATCCAGCCGGGGGTGTCCATGTCGTGGGCCGTGACCCGCGACTCGGGCACCTACCCGGCCGTCCTCCGCCTGGAGATCACCACCACCGGCACGATCCGCACCTTCCAGGCCACGAACCTGCCGACGTGGGTGTCCCTCGACGGCATCAGCTACACCATCTAGGAGGGGCGCGTGCCCGACGTCGACCAGTACGGACAGGGCATCGGCATCTGGCAGATGACCGACGCCCCCAGCATCCCCGACGCCGTGAAGCTGCTCGCCGCCGGCGTCATCCCGCGCGGCGTGATGCGTTTCGCCTCTGCGTCCGCTCGCAGCGCCACCCTCGTCGGCGCCCAGGCGCCCGTCGACGGCATGCTCACCTGGCTCGACGACGTGAAGCGCCTGGAGCTCCGGTCCGAGGGCGCCTGGGTCGTGGTGTCCGTTGGGACCCGGGCCTGGACCACGGTGCCGCTGGCCTCCGGGTGGGCCCACAACGGGAACTCGCAGGGCACGTTCCAGTACCGCATCGTCAACTTCGCGGGCGAGGACAGCATCATGCTCCGGGGCGGCATCAGCCGCGACTCCTACCCGAGCACGATCCCCGGGTCCTTCACCCTCAACACGACCACGCTGCCCGCCTCAGCCCGGCCCAGCACCCTGCGGACCATCGTCGTGCCCTGCTCCGACGTGAGCTCCGACCGCATCACGATGAAGTTGGACATCACCCCCGCCGGCCAGCTCATCCTCTACGGCATCACCAGCACGGCCAAGCCGCCGTGGATCGGCTTCAACGGGTGCTTCGCCAGCCTCTGACCGACCGGCCCCGGCAGGGGCCTTCCTCATTTCAGGAGCCTGTATGGCCACACCCCTGTCCCCGGACCGGTTCATCGCCATCCTGCGAGCGGAGGGCGTCCGCGTCGAGGAGTACCCGGACTGGCGCACCCGCGAGCGCGACGACGAGACCGGGCTCGCCTTCGGACCCGTCCGCATGATCCTCAACCACCACACCGCCGGCCGGAACTCCCTCGGCATCGTCGCCAAGACCGGCGTACCGGGCCTCCCACCGCCCCTCGCGCACATCCACCTGGCGAAGGACGGCGTCGCTACGATGTGCTCGGCCGGCCGCGCGAACCACGCCGGGCCGATGGCGGTCAACGCCTACCAGTCCTTCCGCGACGAGAAGACCGTCCACCCGGCGCCGTCCAAGGCGTCGGGCACGATCGACGGCAACGACATCTCCTACGGCATCGAGACCGAGAACCTCGGCGACGGCAAGGACCCGTACCCGCGCGCCCAGTACGACGCGTGGGTCCGCATCAACGCCGCGATCTGCCGCGAGTACGGCTGGGGCGCCGAGTCGTGCGGCTGCCACAAGGAGACCAGCGTCGAGGGCAAGGTGGACCCCCGCGGCCCGGTCGAGGGCTACGGCGCCCGCGGCCGGTTCGAGTTCACGCCGAAGCAGTTCCGCGCCGACGTCGCCGAGCGGCTCAAGCACCCAGCGTCCTGGAGCCCGGGCGCCACGACCCCCGGCAAGACCACCACCAAGGAGCCCCTCGTGGCCGACAAGAACGACGTGAAGACCCTGTTCACCACGGATGGCGTCCTCTCCTCGCCCGACGGCGACAAGGACAAGCAGGGCAACCGCCACTGGACCGCCGAGAGCTACCTCCGCTACGGCTTCCTCCAGGACCGCGAGACGAACTCCCTCGTGAAGAACCTCGCGAAGCAGGTCGCCGCCCTCCAGGCCGCCGTCGACAAGCTCAGCAAGGAGGCGTGACCGTGAGGATCTTCGGACGCGAGCCCGCGCTCGTCATCGCCGCCGTCTCGGCCGGCCTCAGTCTGCTCGTCACGTTCGGCTTCGGCCTGTCCGCCGAGCAGGCCGGGGCAATCGTCGCCGTCATCTCCGCTGTGTTCGCCGCCGCGACCGCGGCCGTCACGCGCCCGATCGCGCCGTCAGCGTTCACCGGGCTCGTCGCCGCGGTCGCTGCGCTCCTCGCCGCCTACGGCCTGGAACTGCCCACCGAGCAGATCGGCGCCATCAACACCGTCGTCCTCGCCGGGCTCGCCCTGCTGACCCGCGGGCAGGTCTCCCCGGCCCGACCCTCCGCGCCAGCCACCACCGAACCGCCGCGGGCGATCTGATGCCGTGCCGTGCCGCCCGGCGCCTGCACAGGGCCCTGGGCCGCCGCGGCGTCTTCCTCCTCATCCTCGGCGTCGGCAAGAGCTGCTATGGCCTGTCGTTCCTGCTGACACCCCCTACCGACGGCGGCCTGCAGCTCCTCACCCGGTTCGGCGACCTGCGGCAGTGGTCCTGGCTGTGGATCGTCTGCGGGCTCACCACCCTTGGATCCGCGTTCCTGCGGATCGGCCGCGACAAACTGGGCTTCCTCGCCGCACTGACTCCCCCCACGGTGTGGACGATCGCTTACGTCTACGCAGTCTTCGCTGGCGGCTACTCCCGCGGCGGGTTCGTCGCACTCTGGTACCTGACCTCACACATCGGGGTCATCTGTTGGGCGGCCACGGTGCCCGAGTACTCGGTCCCCCCAGCTCCGCGGCCCCAGAGAGGCAGGGCCTGA

Protein sequences of DBSCAN-SWA_5

>NZ_CP010849|6753001:6763672|6762872_6763235_+|WP_044385898.1|DBSCAN-SWA
MRIFGREPALVIAAVSAGLSLLVTFGFGLSAEQAGAIVAVISAVFAAATAAVTRPIAPSAFTGLVAAVAALLAAYGLELPTEQIGAINTVVLAGLALLTRGQVSPARPSAPATTEPPRAI
>NZ_CP010849|6753001:6763672|6753001_6757333_+|WP_044385890.1|DBSCAN-SWA
MAAISVGSVEVDVVPNARGIRRRLQEQVVPAADSVGDEIGRVIGRHVSTQVAQAVRTGVTTGSRTAVPPATRGGEQTGSAFARGMRTRVEAALRSLPEVELTADSSAVDREIHQIRAQLETLRDVEIGVDIDAGEAMARITQLQSRLAALAASDADVDVRIDTGAAAAELAAVQAQVNRLDGDDVTIDVDTRSATANLSMLTTAALAFGPALLPVLPVAAAGLGAMAAAASAAAVGVGALAAVAVPAFVQMGKVLQAQKAAQDAATTATLKGGQAAAQAASRSLQMASAQQALASAHRNAAQQIRQAEQGVADAVRSAAEANRRAKEQLAGAVQQAADRQRRAAEQVRQAEEQLADAQRVAQRAQEDLTQARRDAAAELAELGDRVANARLSERDAALSVQEAEVRLRATQAEGSKATLLERARAQLAYDQAVQRLRESQAETKALTAEKSAADKAGVEGSETVRTAQERLREAEKGVARQQRALAKERADAARQQIESQEAVAEAQRNVARTQEEGAQSVARAQEQLASAQQSAADSIASAQRQIEQASLSAAGGVDQAAIAQAKYEEELAKLTPAARETFDAFLNLRDAFSQWSRSLQPAVMPIFTRALIGLKNALPGLTPFVLEAAGAIETLMDKASAELKRPFWADFRSDLQGSVRPAIEGLGVSFGNVFKGMAGVISAFLPKVDSVSARMQTLTGRFAAWGQGLKGSPEFERFLGYSAEMAPRIWEALQRISGALLSIGVAMSPISSVVLTVIGGIAQGVQWIADNAPWAVQAIYGIVVAMGAWRLATLLWTGVTWLATAAMAAFNLAMRLSPLGWIVLGITAVVTAIYLLWTKCDWFRSAVTVIWEAIKMALGAAWDWIKSNVLEPIGTFFTRIVPSWAETLRDKVRVAWDVMKAALALIWDWIKQHVLYPIRDFFIKTMPGWAATLRGRIVGVWDGIRAGISGAWDLIKKWTIYPIRDFFTKTMPGWATSLRDRFIGAFDAARKGIKAAWDRIKGIAREPVQYVVDVVYNRGVRGVWNAVASAFGAPKLDVFKFASGGVMPGYTPGRDVHRFVSPTGGALELSGGEAIMRPEFTRAVGSGFVHTLNAVARSRGAQGVKAALAPMLGGNPRTPTDTSLRYSTGGIYPVQRFASGGIFDWIKSAGSAALGAGSAAWNKIKEGASWLTDTLEASARAGVKNVVDPLLASFPGMDTGFGKMIRRIPSRIVDALFGYSKEADKRGAGGIGGPRIQKALAWARTQNGKPYQWGGNGNPSWDCSGFMSAIESVIRGQKPHRRWATMAFSGRTAPPGWKLRQKSPFMIGITNAGVGHTAGTLGGVNVESRGGDGVVVGRRARGYNDRLFTDWYGFKPGSYDSGGYLQPGFNLAYNGTGRPEPVFTTAQANALTSLAARGGSSGPTTLEGSLYLDSGEFLGRVRGEAQQVMQQGQRELISVINAS
>NZ_CP010849|6753001:6763672|6757343_6759569_+|WP_044385892.1|DBSCAN-SWA
MAIPGNFLSPTTESIDPNTSGWAPKSNCTLAKGVGGRNGDGCLVVKSVASGETQARTVSSYPITPGTVYYCFADAAGSVPERIGIRWLTAAGAEISVTWSLTTMAASANWHRVSAAGPAPVNAATAQVLLSSTETAAGVNHYWENVYLGLPIRILGNLFDFNTESAEIDLSGWAAGANATISRQAPTMGWTVTNYTAGGQVLAVTASAAGTASAMTVNRPAVTPGTEYIAYAYLQPPTTSSTAWIELRFYDSTGAQVGVQRSTLAPPGTGMYRQRASMVAPAAAATCAVAAGLDGATAGQVLRLETVAVTVAPKLMTGSVLPYADSSFEQGVADWATAAGVATLARTTPWGSSSYEGAYALAVTSSTATTSTVRSARWPVTPNVNWRAQAIMRTAGGTWASVTVRVRWYDAGGADLGASTGVGYVLAGTGWYACAADAVAPEAAAQAAVELMPAASVAGSVLHVDAVTLWQVLPQTAVEARPDDGYVLLTLRELPLDYLITVYRVTPDGKRAAVRGAAGLIVQQVITSDVMLIEDHEAPLGQPVNYRIEVYTTAGAVAFTRSSEPVTLALDDINTAWIKDPGNPQRNCLVMVERAPDWQRPIEQAVYVVRGRRNKVILSGRRQGLEGDLAIWTRSDAEREALHLLLDSGNVLLWQAASGMGVADMYVAVGEVTEARVSPLAQEEWRAWSLPLVEQDMPVTTGVNGARGRTWQDVVTEFATAADLLEVYATSEALLLDRRTG
>NZ_CP010849|6753001:6763672|6760661_6761276_+|WP_044385896.1|DBSCAN-SWA
MTALPNRPAPAVHRDLAWALKQQATRAGEGAPSVRGSDWRLATVTAVNADGTVAVDGIPAVRCMPTYTLPAIDDVIVIDQSSSGNWLAWGRTATTAQTWTTLALASGFQNPGHGHTPAYLREGRRIWLRGRIGPTSGSIADGATLLTLPAAIQPGVSMSWAVTRDSGTYPAVLRLEITTTGTIRTFQATNLPTWVSLDGISYTI
>NZ_CP010849|6753001:6763672|6763234_6763672_+|WP_044385900.1|DBSCAN-SWA
MPCRAARRLHRALGRRGVFLLILGVGKSCYGLSFLLTPPTDGGLQLLTRFGDLRQWSWLWIVCGLTTLGSAFLRIGRDKLGFLAALTPPTVWTIAYVYAVFAGGYSRGGFVALWYLTSHIGVICWAATVPEYSVPPAPRPQRGRA
>NZ_CP010849|6753001:6763672|6761949_6762870_+|WP_052808718.1|DBSCAN-SWA
MATPLSPDRFIAILRAEGVRVEEYPDWRTRERDDETGLAFGPVRMILNHHTAGRNSLGIVAKTGVPGLPPPLAHIHLAKDGVATMCSAGRANHAGPMAVNAYQSFRDEKTVHPAPSKASGTIDGNDISYGIETENLGDGKDPYPRAQYDAWVRINAAICREYGWGAESCGCHKETSVEGKVDPRGPVEGYGARGRFEFTPKQFRADVAERLKHPASWSPGATTPGKTTTKEPLVADKNDVKTLFTTDGVLSSPDGDKDKQGNRHWTAESYLRYGFLQDRETNSLVKNLAKQVAALQAAVDKLSKEA
>NZ_CP010849|6753001:6763672|6759573_6760665_+|WP_044385894.1|DBSCAN-SWA
MYPVSDRFLTRLAESHRVATQVQLFLTTGEVVELEHTGGSVTVDRGQAIRRTCTVTVADPSLIPRTPTDQLATYGARLRISRGVEYGDGTSELVPLGVFRLDSVDGDVAEGPVSLQGKDLSAIVADDKLTAPYSASGTVVGAVTALIQRSIPDADIISLIDDAPIGRRTFDIEADPWAGAQEIAAAAGAEVYCNADGVFTIGRLPDLLTAEPVWAVEATEGGVYIKANRAMSSDKVFNGVLARGENTSENTPPVSYLAVDNDPGSPTYWGGPFGRRPKFISSSAYTTTNACAQAANLELAKGRAPNASGDISSLPNSALEPGDIIRVMHPDGARELHQAAAFTVPLDEGSDFPISTVSAKEDA
>NZ_CP010849|6753001:6763672|6761285_6761906_+|WP_052808717.1|DBSCAN-SWA
MPDVDQYGQGIGIWQMTDAPSIPDAVKLLAAGVIPRGVMRFASASARSATLVGAQAPVDGMLTWLDDVKRLELRSEGAWVVVSVGTRAWTTVPLASGWAHNGNSQGTFQYRIVNFAGEDSIMLRGGISRDSYPSTIPGSFTLNTTTLPASARPSTLRTIVVPCSDVSSDRITMKLDITPAGQLILYGITSTAKPPWIGFNGCFASL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044385890.1|6753001_6757333_+	hypothetical protein	A0A2H5BLS1	Streptomyces_phage	1.2e-100	50.8
WP_044385892.1|6757343_6759569_+	hypothetical protein	Q6VY41	Streptomyces_phage	1.8e-196	50.7
WP_044385894.1|6759573_6760665_+	DUF5047 domain-containing protein	Q6VY40	Streptomyces_phage	5.4e-106	54.0
WP_044385896.1|6760661_6761276_+	hypothetical protein	NA	NA	NA	NA
WP_052808717.1|6761285_6761906_+	hypothetical protein	A0A2H5BLW8	Streptomyces_phage	2.7e-62	58.7
WP_052808718.1|6761949_6762870_+	N-acetylmuramoyl-L-alanine amidase	A0A291LGZ3	Streptomyces_phage	4.4e-53	53.5
WP_044385898.1|6762872_6763235_+	hypothetical protein	NA	NA	NA	NA
WP_044385900.1|6763234_6763672_+	hypothetical protein	Q6VY36	Streptomyces_phage	1.4e-49	65.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NZ_CP010849.1|WP_044384527.1|5741459_5741753_+|WXG100-family-type-VII-secretion-target	5741459_5741753_+	97 aa aa	NA	NA	NA	5706444-5756901	yes

Protein sequences of NZ_CP010849.1|WP_044384527.1|5741459_5741753_+|WXG100-family-type-VII-secretion-target

>NZ_CP010849.1|WP_044384527.1|5741459_5741753_+|WXG100-family-type-VII-secretion-target
MSGQILVNFQTISQAAQDVRSTANNIRRQLDELEAGVAKIATSWEGQAQEAYRAKQAEWDQRANSMQQTLEAIAKALDGAAQNYQATEQKNASIWGG

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP010849_9	Orphan	9.8|2927417|19|NZ_CP010849|CRISPRCasFinder	2927417-2927435	19	5722634-5722652	2

1. spacer 9.8|2927417|19|NZ_CP010849|CRISPRCasFinder matches to NZ_CP010849 position: 5722634-5722652, mismatch: 2

ccgccgcccggtcggaccg	CRISPR spacer
ccgccgcccgctcggcccg	Protospacer
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