CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP010950	Aeromonas hydrophila strain AL06-06 isolate Goldfish plasmid pAH06-06-3, complete sequence	0 crisprs	NA	0	0
NZ_CP010947	Aeromonas hydrophila strain AL06-06 isolate Goldfish chromosome, complete genome	9 crisprs	WYL,csa3,DEDDh,DinG,cas3	1	5
NZ_CP010949	Aeromonas hydrophila strain AL06-06 isolate Goldfish plasmid pAH06-06-2, complete sequence	0 crisprs	NA	0	0
NZ_CP010948	Aeromonas hydrophila strain AL06-06 isolate Goldfish plasmid pAH06-06-1, complete sequence	0 crisprs	NA	0	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP010947_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_1

1100133-1100244

Orphan

Consensus_repeat	Method
AGCAGCCGCACTTGTTTGCCCTGTTACTTGGCGATGCGCTTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_1

>merge|NZ_CP010947|1|1100133-1100244|CRISPRCasFinder
AGCAGCCGCACTTGTTTGCCCTGTTACTTGGCGATGCGCTTGTCGTGGTGGAAACGGTGCGGCTGATGTAGCAGCCGTACTTGTTTGCCCTGTTACTTGGCGATGCGCTTGT

>NZ_CP010947|1|1|1100133-1100244|CRISPRCasFinder
AGCAGCCGCACTTGTTTGCCCTGTTACTTGGCGATGCGCTTGT	CGTGGTGGAAACGGTGCGGCTGATGT
AGCAGCCGTACTTGTTTGCCCTGTTACTTGGCGATGCGCTTGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_044799293.1\|1089691_1090519_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP010947.1\|WP_044799296.1\|1095439_1096450_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|225719
NZ_CP010947.1\|WP_044799301.1\|1103365_1104202_-\|5'-methylthioadenosine-nucleosidase	unknown	unknown	gnl\|CDD\|350170
NZ_CP010947.1\|WP_052508922.1\|1106061_1107000_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176140
NZ_CP010947.1\|WP_044801155.1\|1107330_1108158_+\|xanthosine-phosphorylase	unknown	unknown	gnl\|CDD\|236183
NZ_CP010947.1\|WP_044799300.1\|1102765_1103275_+\|YgjV-family-protein	unknown	unknown	gnl\|CDD\|378474
NZ_CP010947.1\|WP_011704885.1\|1097134_1097965_+\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP010947.1\|WP_044799294.1\|1090508_1091504_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP010947.1\|WP_044799299.1\|1102132_1102708_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_CP010947.1\|WP_029303826.1\|1104309_1105164_-\|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|381594
NZ_CP010947.1\|WP_043168429.1\|1091503_1092802_-\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP010947.1\|WP_044799303.1\|1108183_1109443_+\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NZ_CP010947.1\|WP_017410319.1\|1099659_1099992_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044799295.1\|1092832_1095265_-\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP010947.1\|WP_044799297.1\|1096446_1097115_+\|nucleotidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|133044
NZ_CP010947.1\|WP_044799305.1\|1110365_1111277_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP010947.1\|WP_017782097.1\|1105717_1105906_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044799298.1\|1098051_1099395_-\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP010947.1\|WP_044799292.1\|1089324_1089687_-\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP010947.1\|WP_044799304.1\|1109505_1110309_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|235387

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_044799293.1\|1089691_1090519_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	2.04685e-147
NZ_CP010947.1\|WP_044799296.1\|1095439_1096450_+\|phosphotransferase	gnl\|CDD\|225719	COG3178, COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only].	3.92152e-74
NZ_CP010947.1\|WP_044799301.1\|1103365_1104202_-\|5'-methylthioadenosine-nucleosidase	gnl\|CDD\|350170	cd17877, NP_MTAN-like, nucleoside phosphorylases similar to 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs), as well as futalosine nucleosidase and adenosylhopane nucleosidase. Bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	3.62259e-65
NZ_CP010947.1\|WP_052508922.1\|1106061_1107000_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176140	cd08449, PBP2_XapR, The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold. In Escherichia coli, XapR is a positive regulator for the expression of xapA gene, encoding xanthosine phosphorylase, and xapB gene, encoding a polypeptide similar to the nucleotide transport protein NupG. As an operon, the expression of both xapA and xapB is fully dependent on the presence of both XapR and the inducer xanthosine. Expression of the xapR is constitutive but not auto-regulated, unlike many other LysR family proteins. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.47718e-98
NZ_CP010947.1\|WP_044801155.1\|1107330_1108158_+\|xanthosine-phosphorylase	gnl\|CDD\|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	1.12051e-148
NZ_CP010947.1\|WP_044799300.1\|1102765_1103275_+\|YgjV-family-protein	gnl\|CDD\|378474	pfam10688, Imp-YgjV, Bacterial inner membrane protein. This is a family of inner membrane proteins. Many of the members are YgjV protein.	9.55339e-43
NZ_CP010947.1\|WP_044799294.1\|1090508_1091504_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP010947.1\|WP_044799299.1\|1102132_1102708_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	8.37551e-16
NZ_CP010947.1\|WP_029303826.1\|1104309_1105164_-\|lytic-transglycosylase-domain-containing-protein	gnl\|CDD\|381594	cd00254, LT-like, lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.45431e-39
NZ_CP010947.1\|WP_043168429.1\|1091503_1092802_-\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	6.70579e-163
NZ_CP010947.1\|WP_044799303.1\|1108183_1109443_+\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	9.28641e-156
NZ_CP010947.1\|WP_011704885.1\|1097134_1097965_+\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	5.81204e-143
NZ_CP010947.1\|WP_044799295.1\|1092832_1095265_-\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP010947.1\|WP_044799297.1\|1096446_1097115_+\|nucleotidyltransferase-family-protein	gnl\|CDD\|133044	cd06422, NTP_transferase_like_1, NTP_transferase_like_1 is a member of the nucleotidyl transferase family. This is a subfamily of nucleotidyl transferases. Nucleotidyl transferases transfer nucleotides onto phosphosugars. The activated sugars are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides. Other subfamilies of nucleotidyl transferases include Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase.	1.58311e-79
NZ_CP010947.1\|WP_044799305.1\|1110365_1111277_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	4.14921e-09
NZ_CP010947.1\|WP_044799304.1\|1109505_1110309_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|235387	PRK05283, PRK05283, deoxyribose-phosphate aldolase; Provisional.	1.67728e-133
NZ_CP010947.1\|WP_044799298.1\|1098051_1099395_-\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.14894e-172
NZ_CP010947.1\|WP_044799292.1\|1089324_1089687_-\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	3.6682e-63

>NZ_CP010947.1|WP_017410319.1|1099659_1099992_-|hypothetical-protein
MTTQPTEKKLTIQIRVEPGCLGPDGKAHIETFCTAAAKIFAAVEPELVNWTLLPRYDKQLPEQEFFIDGRKLTEEQASLFLRRLGRELGEVQETLDSVLAQLVERYFKTL
>NZ_CP010947.1|WP_044799298.1|1098051_1099395_-|NCS2-family-permease
MNQPHQAPAQAAGQGLLERLFALKGHGTNARTEVIAGITTFLTMVYIVFVNPQILSAAGMDTQAVFVTTCLIAGIGSILMGLLANLPIALAPAMGLNAFFAFVVVAGMGYSWQVGMGTIFWGAMGLLILTLLRVRYWLIANIPLTLRVGITAGIGLLIALLGLHNAGIVVASPATMVTVGNLTSLPCLLGLLGFFLICIFSARGVHSAVLIAIVVTTTLGWLFGDVTFKGFVSMPPSIEPVFGQLDLMGSLDISLAGIIFSFMLVNLFDSSGTLIGVTNRAKLADDKGHFPRMKQALLVDSASSVGGAFMGTSSVTAFIESSSGVAVGGRTGLTAIVVGLLFLLAIFFSPVAAMVPAYAAAGALIYVGVLMCSELTRVKWEDLTEAVPAFMTAVMMPFSFSITEGIAVGFISYCVMKAGTGRWREINPCVLVVALLFVLKFVWVDAH
>NZ_CP010947.1|WP_011704885.1|1097134_1097965_+|co-chaperone-DjlA
MRIWGKVLGAFFGFLLGNIFGALLGLWIGHRFDRGMGLNFRRAPTQQQQAVFFHATFAVMGHIAKASGQVTEQEIRVASNLMDRMRLAGEQRARAQESFRQGKEADFPLRETLAEFRRASQGQRDILRFFLEVQLQAAFADGKVEANERAILHTIADELGFSRIELARILAMAEAQMNFFNRAHGGQYQDGGHGGQQYRQEAPSRDRLKDAYQLLGVSESDSDQEIKRAYRKEMSKHHPDKLAAKGLPPEMMEMAKEKTQEIQQAWEWIREARGIR
>NZ_CP010947.1|WP_044799297.1|1096446_1097115_+|nucleotidyltransferase-family-protein
MKAMILAAGRGERMRPLTDSLPKPLLAVGGKPLIVHHIEKLKAAGVTDLVINHAWLGHKLVEALGDGRQFGVDIQWSAEESALETAGGIVQALPLLGAEPFLVINGDTWLDLDYRTLVSQPLGTDLAYLWLVPNPPQHPAGDFALQAGKVVDSPALTFSGVGLYDPAAFAGLTPGARKLAPLLREWMAQGRVGGSLLAGEWRDIGTVARLRALDDQLQGRTH
>NZ_CP010947.1|WP_044799296.1|1095439_1096450_+|phosphotransferase
MHDRDSLLLHWARRISGDASLQLTLISGDASFRRYHRGGGLIWVDANPKTEKNHEFVRNASALNAGGLLAPEVRAVDYEQGLLAVTDLGDTQLIGCLNADNVLAWYGKAIALLPRLGAVELDLEPFDAAFMVRENSIFPEWLLGHHLQLTLSDEEQQLLAETFACLTENNLAQPQGVMHRDFHSRNLMVCGGETPADSRLAVIDFQDMVIGPLSYDLVSLLKDCYVRWPDAVIEQGMRQGFDTLQQAKLLGELDYAAFRRAADLTGMQRHLKAAGIFTRLYHRDGKSGYLKDIPRTLGYVVDVCHSHGATYPVLARFGQWLAQVVLPGLARSGVTS
>NZ_CP010947.1|WP_044799295.1|1092832_1095265_-|LPS-assembly-protein-LptD
MTKRTLGYSYPIALTISLVPALTPAIVQAAPLTPPPATGILDGLCYDYVPKIEKLAPGKDANAQPVEVDADRLEAKQGGTAVYQGDVKVRQGVRKFDSDYAELDQKSRDVIAIGNIYYNDGQITVTSDKTLKSNLDTKNSELEEGKYQVHGSPVRGSADRVTMTNNNQNITLEGAQYTTCPPGQEVWTLKAGSIDIDQTEVFGEAWNASLWLYDYPVFYFPYINFPIKDERKTGLLYPGYTQSSKNGMDITQPFYWNIAPNYDATITSRFMDRRGLMEQVQFRYMPDPAHVGSLYFENLANDKQYDETPSLNQAMSDGHRYLLNANHTSLFADNAMRVSLDYTKVRDRDYNYFNDFSPKVGTQVENQLQQSLMAGYFQPNWNINTEVRTYQILLASAQQPHELMPRIDHNYYQQGSWYDLAWNTEITKFGYNNAQAIAQNQGGAYTGTRVYTAPTLTMPLINEAGYYLDSQYKLMYTRYDQEVPDNMSQTFVSRFTPENGNGVTLDEGIITRTLPSFRLKGGMTFERNQNWFGGDANQTLEPEFQYLYVPYKNQDNIGVYDSTSMRQDYYSLFSDRRYAGLDRISDSNRVSIGLTSRVYDEAGDERIRLAVAQAFDFVAPRVKLYPSETLTTNTRSPLSFEGDAKINEQWFAHAGAQYDVDQSRLSSANSAVEYRREKLISQLNHRFVRDANYDLENKGQVTDLNQIGLLLTTPLNDQWHLYGGYYQELNQSVKSDRKVGLKYDSCCWSINFNLEWVNTPDNVTMRPTSERSLGIQFEMKGLGSVGTGTKGTSLDTEALPYIRPFNLRDQ
>NZ_CP010947.1|WP_043168429.1|1091503_1092802_-|peptidylprolyl-isomerase-SurA
MKKTLISLLTAGLFGAMSQGAFAAPELMDKVLAVVNKDVVLASQQEALVQKVKASAQESGQSLPDDATLRKQALDRLIQESLQLQLADRQGLKISDTQLEQAIQSIAADNKMTLDQLRAQLAREGLTYAQYREEVRREILMNEVRRNQVRRRINISEQEVKQVVDILAKQGQQQQQYHVGHIQVALPDNPSAEQLNAAKSKIERILAALKQGADFRKMAIAESSGPKALEGGDWGWMSPQEMPTLMAEAVQGTKKGDIVGPLRSGAGLHIIKVFDSKGQQQVVQTEVRARHILIKPSIILSEEKAKGMLDGILHDIKSGKASFASLAEKYSEDPGSAVQGGELGWSDPNVYVPEFRDMVNRLQPGQISEPFRTTHGWHIVQLEERRSQDATNKAQEQRAYQLIYNRRFTEESQAWLDELRDEAYIQIEGAGS
>NZ_CP010947.1|WP_044799294.1|1090508_1091504_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MSCRRLAITPGEPAGIGPDLVLQIAQQAWPHQLVVIADPALLRERAALLGLPVELQPYDADQPARPQRAGTLTVCPVPLGAAVVPGMLDEGNGAYVLATLQRACDGNMSGEFAAVVTGPVHKGIINQAGVSFSGHTEFFAQQSGTADVVMLLATEGLRVALATTHIPLAYVAMAITEDRLGKVIRILDADLKSKFGIATPRIYVCGLNPHAGEGGHLGREEIDVIEPALAGLRQEGIDLVGPLPADTLFQDKYLKDADAVLAMYHDQGLPVLKYKGFGSSVNITLGLPFIRTSVDHGTALDLAGKGLADSGSLITAINHAIKMVEKKRYEQ
>NZ_CP010947.1|WP_044799293.1|1089691_1090519_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MSSKVQSNKVHMGHTARKRFGQNFLHDRYVIDQIVAAINPQPGQNLVEIGPGLAALTEPVASQMDKMTVVELDRDLAARLREHPTLKDKLTVIEADAMRFDFGTLMGEGKGPLRIFGNLPYNISTPLIFHLCEFADRVEDMHFMLQKEVVLRLAAGPGSKAYGRLSVMTQYYCQVVPVLEVGPGAFKPAPKVDSAVVRLIPHKNPTIVAKDIRCLNRVCTEGFGQRRKTIRNSFSNFITDAQLTELGIDGNLRPENLSLEQFVMIANWLADQQQA
>NZ_CP010947.1|WP_044799292.1|1089324_1089687_-|Co2+/Mg2+-efflux-protein-ApaG
MALPHIVIRPYPRYVADSKDPYQFHYLIEIENLGPGPVQLLHRRWLITDANGKMLEVEGPGVVGEQPVIAEGETFRYQSGVPLATPLGVMEGSYTLQDESGQQFEAPIAPFTLAVPHIIN
>NZ_CP010947.1|WP_044799299.1|1102132_1102708_+|Crp/Fnr-family-transcriptional-regulator
MTSLPSAPPLAATLAAMGLAPAIGEPLAGRLLRLTLQPGQPLLAQGAIQESAFYIERGIARACHYARDGQERCKEFYFEGELCLLYDSWLSGSPARYQLEAVTTLQLVRVPLALLDEPAWQPVCMALLRQQLCYKERKEAFLLLHSPEERYRELCRTFPHWPARLTQVQLANYIGISPVTLSRIRRRINTG
>NZ_CP010947.1|WP_044799300.1|1102765_1103275_+|YgjV-family-protein
MMSLFLWSQLVVSLALLLDLLSFQLRTRRAILACLALSCALNGAHFALLGQASAALLLWLASLRFVVSMLDTRRLLMWLFMGLSCLAVLATYQGPLALLGLLASLLQTRAAFCPDDRLLRRWMLLGTLCWLANNLLVGSPVAALMEGLFLVSNLVGYYRHYGRRACPGR
>NZ_CP010947.1|WP_044799301.1|1103365_1104202_-|5'-methylthioadenosine-nucleosidase
MNFIKRCSRLLTLFALFSSTVVAANPAPAPILIQGAMDVEVGTLVAALKDKQELTVGAWTYWQGTLSGYPVVVSRTEVGLANAAAATTLAMERFQPRLVINQGTAGGHDPALHRGDIVIGTKSFNMGAYRSDLTPAEQGVDPSKWHNFEVTMRLRDNGKLVEHTAFAGDPELVGRALGMADRYRHGRVVPGIIGTADEWNRQVARINWLHQTYQTAAEEMETSSAALVAEAYKVPFVGIRVLSNTDLHGEEFDPQTAIHCQQFIIDYAKALINGFNKA
>NZ_CP010947.1|WP_029303826.1|1104309_1105164_-|lytic-transglycosylase-domain-containing-protein
MSSSSENRLFLLLFLSLLLAGTGQAAAQSRDFRQAPKALSALKKGQQAQSQGNLTQAIHFYCAAATTGNPEGYFRIGRLLATGPGSVRNPRMANAYLAMAIRLGNQQAARYYNSRVGNAVMGDQCGSGVGGSGGYFAAIPTTPFNLEAYLARQSPAKQKLATMLRHAAKRHRIDERLVLAIAIAESNLDSRAVSPKNAQGLMQLIPETQQRFGVTRPFDPEQNIKGGVAYLKWLHTHFDGNWTLMSAAYNAGEKSVEQYGGIPPYQETQQYVRRVLYFAGHKQP
>NZ_CP010947.1|WP_017782097.1|1105717_1105906_-|hypothetical-protein
MIRILLLLGAALSAYGLQQSHTLAPLLSLLGLLSLWVASEIRLMYRQLPATEPDEQPYHLDV
>NZ_CP010947.1|WP_052508922.1|1106061_1107000_-|LysR-family-transcriptional-regulator
MALDSHWRDRVTLKMLRYFHAVASQGHFSRAALQLNVSKSPLSAQIKELASLLGLALFERHTRQVSLTATGRLLQAECALLFDVLESGLNRVVQAGRMERNQIRIGLVSSIFWAGFGEVIRQCHQRHPEFEITFTELSPERQKQALSRKEIDLGLARFADTVNIHPLLAETIYRESMVLVVSDEHPLRDRKLVSLPELAGEPFVLMSRANSSSTDLIINACLVEGFYPHLNQEVVEPNTLMAVVATSLQVALVPASYARQKWPHVRFIRLEQAIPADLCVLYAPPGDGQPAAVAIRHFIGTMSAQMNRPTAD
>NZ_CP010947.1|WP_044801155.1|1107330_1108158_+|xanthosine-phosphorylase
MQQDPVLNAVATILARKPGFAPRAAMILGSGLGVLADGLEEKVTIPYEELDGFPVSTVAGHSGELVLGKLRGVDVVCMKGRGHYYEHETMKVMTTPVRTFKRLGCELLLVTNAAGSLRPERIGVGSLVIFNDHINTMPGTPMTGANDEAYGPRFFSLANAYDKGLRGEALALAEREGIAVNQGVFVSYSGPCFETAAEIRMMQIIGGDVVGMSVVPEVVSAAHCALPVLAICAITNMAEGLGDVQLSHEQTLKCAKLAETDFIRLINAFIKHHFQ
>NZ_CP010947.1|WP_044799303.1|1108183_1109443_+|NupC/NupG-family-nucleoside-CNT-transporter
MFAAGFLGMAALILIAVIASTNRRAIRLRTVGLALALQVAIGALVLYVPLGRRALEGMAHGVDAVLASGKAGIHFLFGNLVNFSLDGIGFVFALNVLPLVVFFSALIAVLYYLGVMQLVIRFIGGAMARLLGTSQTESMSAVANVFVGQSEAPLVVKPYMPKMSDSEFFAVMCGGMASVSGTVLAGYAMMGVDMQYLLAASFMAAPGGILFAKLIIPETSQPDYVFDNSIQFDGKKPENVLAAAGEGASSGLKLAAAIGAMLIAMIGLVTLVNTLLGGVGEMVGMPLSLELILGWIFSPLAFLLGVPLADIGIAGAMIGKKLVVNEFVAYSDLSPYLKDASTVTAAGLQVLEDKSKVIISFALCGFANLASMGILIGGLGTLCPSRTDFIARYGLRTVLAATCSNLMSAAIAGIFFSLA
>NZ_CP010947.1|WP_044799304.1|1109505_1110309_+|deoxyribose-phosphate-aldolase
MIPATAFAPACAATEAASRAIHLMDLTSLNDDDHDARIIALCHQARTPVGNTAAVCIYPRFVGLARLTLAAQGTPEIKVATVVNFPHGDDELDVVLAETRAALLDGADEIDLVIPWRALKAGDEAPARALVRGCKALCGPRLLKVIIESGELQEPALIRAASLLAIEEGADFIKTSTGKVPVNAIPEACRTMLAAIAECGAQNRVGFKAAGGVRSAQEAGAYLAMAAALFGDEWLVAERFRFGASSLLGQLLATIEGKKPVAASSGY
>NZ_CP010947.1|WP_044799305.1|1110365_1111277_+|EamA-family-transporter
MSHPRFHFVQAHGKVLLFTLLISLSFPIGSSLTAVLDPLVVTWARYLLAALTFVILLACQRRLALPALRDLGRYTLISLPALCYFVAMFVALQETSALDASALYTTVPLISALASMLVLQRRIGWSMAFALLGGMVAAALIIFRGELSQLASLSLTPSNRIYLLGCVGMALNPILVKRYYRGESFAHLTCWTLICATLLLTLVAAPRLLTTDWQRVSLPLWLGLAYLALFATALSFFLFQQGSVVLQPEQVSAYTYLIPVLVLLIGMLSGEEVIWRQVGWGVLGVLLTMAVMVLVPARQARRA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP010947_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_2

1255403-1255513

Orphan

Consensus_repeat	Method
AGGTCAGTGGCAGCAGAGCCTGCAGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_2

>merge|NZ_CP010947|2|1255403-1255513|CRISPRCasFinder
AGGTCAGTGGCAGCAGAGCCTGCAGCCTGACTTTCATGCAAATGGCTCCGGTCCAAACATAGTTGGCGGTACAGTCAGTGCGGCAGGTCAGTGGCAACAGAGCCTGCAGCC

>NZ_CP010947|2|2|1255403-1255513|CRISPRCasFinder
AGGTCAGTGGCAGCAGAGCCTGCAGCC	TGACTTTCATGCAAATGGCTCCGGTCCAAACATAGTTGGCGGTACAGTCAGTGCGGC
AGGTCAGTGGCAACAGAGCCTGCAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_044799379.1\|1246546_1248313_+\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|368641
NZ_CP010947.1\|WP_044799387.1\|1267054_1267825_+\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377050
NZ_CP010947.1\|WP_052508926.1\|1263885_1265913_+\|VENN-motif-pre-toxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|368145
NZ_CP010947.1\|WP_024945707.1\|1243425_1244175_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|239321
NZ_CP010947.1\|WP_158319747.1\|1259598_1260006_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377410
NZ_CP010947.1\|WP_044799384.1\|1262810_1263041_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044799374.1\|1238002_1238560_+\|DUF3833-domain-containing-protein	unknown	unknown	gnl\|CDD\|378992
NZ_CP010947.1\|WP_144406118.1\|1261433_1262135_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044799375.1\|1238684_1239152_+\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP010947.1\|WP_158319746.1\|1245090_1246533_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP010947.1\|WP_144406119.1\|1263132_1263501_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372824
NZ_CP010947.1\|WP_044799380.1\|1248273_1254207_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293785
NZ_CP010947.1\|WP_080891252.1\|1260002_1261259_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377410
NZ_CP010947.1\|WP_044799377.1\|1242225_1243251_+\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|187558
NZ_CP010947.1\|WP_044799385.1\|1263497_1263800_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_144406117.1\|1259092_1259440_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_080891249.1\|1237511_1238003_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374318
NZ_CP010947.1\|WP_044799376.1\|1241121_1242141_+\|hybrid-cluster-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|99811
NZ_CP010947.1\|WP_080891253.1\|1265909_1266401_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379734
NZ_CP010947.1\|WP_044801161.1\|1239357_1241007_+\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_044799379.1\|1246546_1248313_+\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	2.29517e-31
NZ_CP010947.1\|WP_052508926.1\|1263885_1265913_+\|VENN-motif-pre-toxin-domain-containing-protein	gnl\|CDD\|368145	pfam04829, PT-VENN, Pre-toxin domain with VENN motif. This family represents a conserved region found in many bacterial porlymorphic toxins which is located before the C-terminal toxin modules.	8.90972e-14
NZ_CP010947.1\|WP_024945707.1\|1243425_1244175_-\|DsbA-family-protein	gnl\|CDD\|239321	cd03023, DsbA_Com1_like, DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC motif, assumed to be imbedded in a DsbA-like structure. Its homology to DsbA suggests that the protein is a protein disulfide oxidoreductase. The role of such a protein in pathogenesis is unknown.	6.40413e-63
NZ_CP010947.1\|WP_158319747.1\|1259598_1260006_+\|hypothetical-protein	gnl\|CDD\|377410	pfam04830, DUF637, Possible hemagglutinin (DUF637). This family represents a conserved region found in a bacterial protein which may be a hemagglutinin or hemolysin.	1.35098e-07
NZ_CP010947.1\|WP_044799374.1\|1238002_1238560_+\|DUF3833-domain-containing-protein	gnl\|CDD\|378992	pfam12915, DUF3833, Protein of unknown function (DUF3833). This is a family of uncharacterized proteins found in Proteobacteria.	8.6643e-88
NZ_CP010947.1\|WP_144406119.1\|1263132_1263501_+\|hypothetical-protein	gnl\|CDD\|372824	pfam13930, Endonuclea_NS_2, DNA/RNA non-specific endonuclease.	2.87323e-06
NZ_CP010947.1\|WP_044799375.1\|1238684_1239152_+\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	9.92337e-58
NZ_CP010947.1\|WP_158319746.1\|1245090_1246533_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	8.83462e-103
NZ_CP010947.1\|WP_044799380.1\|1248273_1254207_+\|hypothetical-protein	gnl\|CDD\|293785	sd00046, FHA_bHelix, beta-helical repeat found in filamentous hemagglutinin and related adhesins and CdiA family proteins. This model contains ten copies of an approximately 20-residue repeat found in two-partner secretion (TPS) proteins, including the filamentous hemagglutinin (FHA) family of adhesins and CdiA family proteins. These repeats form a right-handed beta-helical structure, and are found in large secreted proteins from a number of plant and animal pathogens. FHA family adhesins bind to various types of cells and may contribute to attachment, aggregation, and pathogenesis. CdiA proteins are involved in contact-dependent growth inhibition (CDI).	1.64807e-08
NZ_CP010947.1\|WP_080891252.1\|1260002_1261259_+\|hypothetical-protein	gnl\|CDD\|377410	pfam04830, DUF637, Possible hemagglutinin (DUF637). This family represents a conserved region found in a bacterial protein which may be a hemagglutinin or hemolysin.	5.59623e-12
NZ_CP010947.1\|WP_044799377.1\|1242225_1243251_+\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|187558	cd05247, UDP_G4E_1_SDR_e, UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NZ_CP010947.1\|WP_044799387.1\|1267054_1267825_+\|LuxR-family-transcriptional-regulator	gnl\|CDD\|377050	pfam03472, Autoind_bind, Autoinducer binding domain. This domain is found a a large family of transcriptional regulators. This domain specifically binds to autoinducer molecules.	7.01189e-38
NZ_CP010947.1\|WP_080891249.1\|1237511_1238003_+\|hypothetical-protein	gnl\|CDD\|374318	pfam16036, Chalcone_3, Chalcone isomerase-like. Chalcone_3 is a family of largely bacterial members.	4.38861e-05
NZ_CP010947.1\|WP_044799376.1\|1241121_1242141_+\|hybrid-cluster-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|99811	cd06215, FNR_iron_sulfur_binding_1, Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria in which they participate in a wide variety of redox metabolic pathways. The C-terminal portion of the FAD/NAD binding domain contains most of the NADP(H) binding residues and the N-terminal sub-domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap betweed the two domains. In this ferredoxin like sub-group, the FAD/NAD sub-domains is typically fused to a C-terminal iron-sulfur binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins which act as electron carriers in photosynthesis and ferredoxins which participate in redox chains from bacteria to mammals. Ferredoxin reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	9.8128e-118
NZ_CP010947.1\|WP_080891253.1\|1265909_1266401_+\|hypothetical-protein	gnl\|CDD\|379734	pfam15593, Imm42, Immunity protein 42. A predicted immunity protein with an alpha+beta fold. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Ntox18 family.	5.62276e-30
NZ_CP010947.1\|WP_044801161.1\|1239357_1241007_+\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0

>NZ_CP010947.1|WP_044799380.1|1248273_1254207_+|hypothetical-protein
MQNQGSLAGGDSLTLQADTLDNEGRIASQLATLTGRQLRSSGTLLGVSRLTLKGDELALTGQQLTDGELELGSRLLQLSGQSLVGGQARVTTETGNFDGVLKAQSLVLAVKDATSEGKLHSREGIAWEGQRLATGSASELLANRGVSLSGDQLALGGAVGAGQDMAIKGRQVTQHGRLISGQTLNVDTDGLLLEGETEAAAFNVHSNELTVAGKVKGNTVQLQAGVLTNRGEVQAGQTLNWQGSRLANSGTLQGDQQLVLKGDALQNQGSLAGGDSLTLQADTLDNEGRIASQLATLTGRQLRSSGTLLGVSRLTLKGDELALTGQQLTDGELELGSRLLQLSGQSLVGGQARVTTETGNFDGVLKAQSLVLAVKDATSEGKLHSREGIAWEGQRLATGSASELLANRGVSLSGDQLALGGAVGAGQDMAIKGRQVTQHGQLASGQVMKVDADELALAGEVQGRAITLTSERAAQQGRILATDTLNWHSKQLDGNGWLQAGQALNLNGERLTHSGTAVTAGKLALTFAELNSTGGLFADEVAVTGARLLLKGVLESKSSAQITADELQLGGELRTGADLALGATLLTLSGSQHVGGNLQLQAEQAEVSGELEVGKLLKLDAKTLASSGKLLANQADIAAVNWQQRSELTTDNALVWRGDKLTQEAGGALRAGGVLNLSGDDITLAGDVAAKGDVAVVANAYQQQGTMNAALGLCIDATRLQLDGTTQAKTAQLHSQVGSSRGQHLIGQQFNWQSDTLANQGWLQAGDSLALTGRTLDNEGTVIAGGDHQLNATERLTNQGNLAGKTLSLTTKALQNGGLLQGKQGITLQAKEATLTGRLVSQGAVQLGAKLLALGGNANIGGALTLQGETQQLAGVWRVGGLLQSTGKQLTLTGDWQAGQWQLQADTLTNKGRLASEQAANFEVTEWHNEQGATLVAAGPLSLTGQRLLQQGSWLGNGSQTLMVDEITQQGQWLGDGALQVKGSKLVNSGTLRAAGLDLTVNELENRSRMESGGELNWQGMQWRNLGALLAGHATLTGDTLLNSGDVGARQLTMKAATRLDNRGVLVGKEGINLTAATLDSQGDMLSNGSMQLGASLLSLNGLTQANGELVVTAEQATLAGNLAADQLQWRGKTLVMSGTAAARDATLNGEQVTLDGTLKGDHQQVTATTLTTGQQSQLLAKAGQQLTAGQMTLQGSAVAGGAQRIDATQLSQQGVLASGGSLSLQVADTLLNDGKVSAQAITLTAAHIDNGGALVSKDALNLKTGTLTNRGHWQSDQGITLTANRLLNSGQWVSGLGQTLTLDALDNSGTLLAGAGLTINAPQLSSSGKLLANKDLVLNTNEAMLGSGSTTASNGQLQLHAGTLTSQGTLSSAGDLSWQGANLVHSGSAVTNGALTLQGESVTLDGDLQGERVLLDTGTLTSRGKLTSRGDLAVNARGAVQHHGQLQGNQVVLRSASWQGSGGVGSGGALELRTGQLQLAGPWRIRGEAGIQADTMTLGGSLVSGGNLTLASRGALTSQAGSQLVSGGVLSLDGGTLTQQGLWQSARGMSLKSSRFEQQGDLLAGGDLLLRSGYWQQGGKTRANGGLNAELTEGATLAGTVQTDGNATLLAPALTLKGTLAAKGNVALSANTLISQLGNLLSGGELAMNAARIEQQGRVETTRLQSGGALQNDGVMLVTGQGSISGARLDNRGTLQGDGLTISSRQLDNRGALLGNTLTLTHDTLVNRGRVQGGTLNLTTQQLDNSQGAILRGQHAGDITATTLANAGELSSAGQLLLKGNHLDNSGLISANLLEASPLARLANSGTLFGQQLTLRSGELYAPGKILAGQKATLDAGRVTAIGEWLSGGDLALKTGSSLTSQGTLSAKGMLDLQVQGDWQHQGQWGAGQRFNAGVTGQLNNRGALVSNGVMQLGAQRLENSGSVQSGQGLTLNTQGELRNTGMLASQGDLGWQGESLFNGGTVFSGGSKRSPQIAI
>NZ_CP010947.1|WP_044799379.1|1246546_1248313_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MSTPKLPLTLRLLAYHLSALLALQPAHPAFAEGIAVATGSTTLNQAGNGVPVVDIATPNGAGVSHNLYQDFNVAQPGVILNNTTGQLTQTQLGGLIQNNPHLTGAPANVIINEVVGANPSQLQGYLEVAGQQAGVVVANPNGLTCDGCGFINTPNVTLSTGKPVLDAHGQLQMLDVKQGALTVGGKGLDGSRQASVDLIARAVQLNGALHGKEVNVIAGANTVNRQTGEIRAQQGDGTVPEVAIDTAAMGGMYAGKIRLVSTEQGVGVNLANAVATQGDLTLDANGKIRLRDSSSAGNLQVSSQGELAVTGAIHSGGAAKLAAGGELTAQDADIAAKGDATLQARAQQLQRTKVSSGGTLALQANDALVVREGELQGETLHATAQQLDTQSALTAKDVTLQAEQLRQAGHVQGTSVRLTAGVLRHEGTTQAAQNLTIDATTLDNQGTLKSGQAMSVALGERGHNAGELSAGDNLTIRAGTRWEQGEQGKSNAGQRLQLQAQQVSLAGEVGAPTLDINGNELTVAGKVKGNSVQLQAGVLTNRGEVQAGQSLNWQGVDWPTAAPCKGTNNWCSRGMPCRTRALWREATA
>NZ_CP010947.1|WP_158319746.1|1245090_1246533_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MVTAIRFEGADQLDADARTTLTRPFLHTCMGLPHINALIRDVSQWYLAQGFITSRAFLPEQDLASGTLTIAVLEGRVERIVVDGQPDRITRTLFPGLVGEVLNLRDLEQGVDQLSRLRTLSYQLDIQPGTAAGQSIVNLKGSRRLPLQGSLEFDNSGQQSTGEEQGRMSLSADNLWSLAEQWSLGGSRSTDGRAAHDATSWQSGLSLPYGYWLFDAGYQYSDYRNDLLSRGYVYDSRGNTRTSTGTLSRTLYRDGQSKVSAVLGITHRQSRNFIMEQLLESSSYRLSSLRGGLNLATRVDHHFFTLNPTLTLGTDWFGADSDRGRPVAAPRAQFEKWGLFGSYSTAWQQLGWLSTLYGQWSPDTLYSVERVSLGGDASVRGFKEQSLSGDVGGYLRNELSWQAQTPAWLGQWRGWLALDMGRVDLGNQGDRWRGMVGTALGWEQRYRHVAGNLSVGFPISAPAWLNADPYVVNYRLSINF
>NZ_CP010947.1|WP_024945707.1|1243425_1244175_-|DsbA-family-protein
MKIKHALLCALTGATLLAAPVQASELTKSDVEQIVRDYLVKNPEILVEMSNALRAKQESQQAANDKTLIKAHAKQLYSNQDPESGNPKGSLTVVEFFDYNCGYCKRAHPLIKQLLAEDKDIRYIYKQFPILSETSYFAARAALAVQLGQPDKYQAFHEKLYAHQGPLADEAQVKQLAEAAGVNWSKVEAKIKDGSIDQNLGTNRALAEAMSISGTPAFIIGDQILRGAPRDLASLKGFIKDVRAGKSIQ
>NZ_CP010947.1|WP_044799377.1|1242225_1243251_+|UDP-glucose-4-epimerase-GalE
MTILVTGGAGYIGSHTLVELLNVGQQVVVLDNLSNSSPESLKRVERITGKPVIFVEGDVLDRACLQQLFAAHQIESVIHFAGLKAVGESSQIPLTYYQNNITGTLVLCEEMAKAGVFRLVFSSSATVYGDPASVPLREDFPTSATNPYGRSKLMVEEILRDLAKSDPRWAIVLLRYFNPVGAHESGLIGEDPNGIPNNLLPYISQVGVGKLKELGVFGNDYPTPDGTGVRDYIHVVDLAIGHLKALARIASDTGVFTYNLGTGQGYSVLEMIKAFEAASGRTIPYQIKPRRPGDIAECWAEPHKARAELGWQAERGLERMMIDTWRWQSQNPNGYGPAAKP
>NZ_CP010947.1|WP_044799376.1|1241121_1242141_+|hybrid-cluster-NAD(P)-dependent-oxidoreductase
MTSTSLTLRCIGRRADTHDVASWQFVPQTGSLPAVLAGQCVTLHTEIDGKPHCRAYTLSSSPQDACWQVTIKDVGLVSHHLHQTLQVGDEIRVDGPFGDFNLTALPCERPLLLSAGSGITPMWAMLRDELAKRPDADIRFIHSARSPEDVIFADDLAALAAAHSGVRHALVLEQVGEEAPTAYPWVGRLTPEMLRELAPDLLARHVYLCGPAPYMTAVCTMLAELGLPAAQLHQESFGLPAGASSAAPVAAGSDHFWLTLKKSGKKVKILPGQTLLAALEGAGETMMAACRAGVCGACRCTTEGEIERQSVMTLSAQDLESGVALACSCTASGDVSVDY
>NZ_CP010947.1|WP_044801161.1|1239357_1241007_+|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCAYAQGMCGKTAETSDLQDVLIYTLQGLSAWALAAREHGIVDSEIDAFVPKAFFATLTNVNFDSARIVAYVNQALSYRQQLAAKLAPLAVQADALPAAARFEPGADLLAQLAQAPQTAVNRGKNEVNEDIMGLRLLCLYGLKGAAAYMEHARVLDQQDAGVAAEFHRIMSWLGTDPSDLDPLFKCAMDIGLLNFKIMEMLDLGETTAFGHPEPTQVRVTPVPGKCILVSGHDMVDLKLILEQTKGTGINVYTHGEMLPALAYPFFKQYPHLVGNYGSAWQNQQKEFANFPGAVVMTSNCIIDPNVGNYSDRIFTRSIVGWPGVTHLEGEDFSAVIAKAQALEGFKHVELEHFITIGFARNALMQAAPAVIDKVKAGEISHFFLVGGCDGDRAERAYYTEFAKAIPQDSLLLTLGCGKYKFNKLDFGDIGGIPRLLDVGQCNDAYSAIQLALALSEAFECGVNDLPLTLVLSWFEQKAIVILLTLLALGVKDIRTGPTAPAFLTPALLKVLEEQFGLKGTTTAEADLAEILVA
>NZ_CP010947.1|WP_044799375.1|1238684_1239152_+|DNA-starvation/stationary-phase-protection-protein
MKSPIGLDTVQSQALAAELNKLLASYQILYMNVRGFHWNIRGNQFFELHLKFEEIYNDLLLKVDALAERILTLDGVPLHSFSDYLKVSTIPELKGLHDGRACVESLLESFRELLVAQRRILGQAADAGDEGTASILSDYVQQQEKLVWMLRAYLA
>NZ_CP010947.1|WP_044799374.1|1238002_1238560_+|DUF3833-domain-containing-protein
MQKGFMKYIHAWRYLLLLPLMLLAGCGSSLEDYRCQGPEWDLARFFNGKLTAHGLVTDRSGEVTSRFRVEMRGHWQGDKGELFEQFYFDDGRQQTRTWFLSKGADGHWRGTAADVVGEAVGKTAGFALNWRYQLDLVLLDGSVVRVSFDDWMYLLDENRLLNRAAISKFGIQLGEVLLYIERQPE
>NZ_CP010947.1|WP_080891249.1|1237511_1238003_+|hypothetical-protein
MSLPLTPFAQTGQALVTPWQQLQPVGRGEMSWLWFKLYDATLYSENGRYRPGHYPQALSLTYARAIERDDLLSATAAEWQRLGLGSEQQRQGWLGQLAALWPNVQAGDRLTFYVDRGGAGHFWWRDKPLGTLADPQFSAAFLAIWLAQGSRDPALTRRLRGVR
>NZ_CP010947.1|WP_144406117.1|1259092_1259440_+|hypothetical-protein
MNKNIFEIADGLITINDKAVNLPYPVVEAITIGEVVVVRIEPAVGELCNANIYGFTINGCFKWKIEESPHGTEPDKPFTSIYISPNGKLIAGNWNGIDYAVDVKSGAISAVAFNK
>NZ_CP010947.1|WP_158319747.1|1259598_1260006_+|hypothetical-protein
MEAVQEAYEQWNYSQQSLSPIASAMIAIALAAATGGAGALAMGAAEGTATAAAMANAAFSTLVSQATISTINNGGNLGAVLKDMGSSASIKQLATSVAVRGCCKGWTMRWGGRKRLMQPANLRAPICSPEIPSTG
>NZ_CP010947.1|WP_080891252.1|1260002_1261259_+|hypothetical-protein
MTSHSVVTAGINTTINGSHFADAFKASLLSNIQGEVGKATANWIGAQGIQFDTANSPLAGARKIAAHGVTNGAIAEITGGKFAAGAAGGAMSEHASNWSSQVFSDTEHQVALNKVLGGLAAVAVTGDQNQFDTGAERAETVYRYNSLQHMFNLAAEAKMADVNRGVEPIIKKADEEAKKETLKETLKTSAYIVGAVYLGPAAAVESVLSGSSISTMANVAYQWYDLSQPGNENKSWNYLGSANTAVTGALAPGRGIKGNIGIAIGSSLVSDDFSIDKAGVSGGGAALVGAYGKYIPGLSNKILKGDKIPGFVFEITGSLSGEFFTGYSNKLLLERVEKKRGHEMKYYLGLWLYSCLFFVLLCFLIGGASSIAFYFKEGEFIVPKGEVERGVTFGFIAGTSISIYVFVVSLFKKSEKKE
>NZ_CP010947.1|WP_144406118.1|1261433_1262135_+|hypothetical-protein
MAVTGDQNQFDTGADRAETVERYNNHAYALAALKARYPEKYAKLMDEKQKEFKSCGESPECKNVAIAGFGLVGLPRLSSELLLAAGIGGSASTGFQLWDNNWDISKVDAREAVFSAYLSAGTVGWVFLLTVGSNGAGGAYMSYIKGEDPLNGGVSSGVGAGLGYGLGKLIEIPLDIKMNPSYKNYEWIDIGLGITKQPASNITPSTIGNVVSSVPSEWTSKVGEEKIKDEFKK
>NZ_CP010947.1|WP_044799384.1|1262810_1263041_+|hypothetical-protein
MTLGYIVVDRLEKTAVGGFDVFKISKEAFSIYQDPELSLTENLDMVLLSLIAMEDGPEFEMIEKEFWILLSEIRQM
>NZ_CP010947.1|WP_144406119.1|1263132_1263501_+|hypothetical-protein
MTIARSRQISLQMRLTTTWWAAVCDVGGHVQACSQGGTCDSYNLFPQDKNFNNSEYKVFYENEIKRALDDPSKTVGQTKVVFVRDNPESVRPTALTVTFKIDGVVTERTFLNEAGKSPGTSK
>NZ_CP010947.1|WP_044799385.1|1263497_1263800_+|hypothetical-protein
MITEDFTLANKLFAIVDEGIVDGYDFFSYKIDIGDGYIDAVLTVENEGVITTDAKRDVNNAEVLGIMMKLKGNSISRGDNWRTLIISYRHGEQVKLNFNQ
>NZ_CP010947.1|WP_052508926.1|1263885_1265913_+|VENN-motif-pre-toxin-domain-containing-protein
MLGDQVSGNKVDSDIGYNMALISQQDNDHYQSQQSSISAGGSFTFGSMTASGYVNASRQKINSDFESVVEQTGVFAGKQGFDVRVGEHTQLNGAVLAGSEDAGKNHLSTGTLGWNDLVNRAEYKVESQSVGISGSGDSTKGFSSIAAMTSLGGSNSSGSASSTTFASIGAGDIEIRNTAGQQQDLVSLHRDPTLAVNRLSPIFDKQKELARMQEAQLIGEVGKQATQMVVSHHLAAANEKAKDDPEYANSKEYKALQEKWGVGSDFQRGIQAATAALQGLAGGDLTQAAAGAAVPYLAQMVKQQTDDGPSRVMAHALVQGALAAAQNKNAMVSATGAATGELAGMMATELYHKEASQLTEGEKETVSTLATLAAGLAGGLTGDSTASALGSAQTGKTVVENNLLAKELVEGCAIASPCRTKVAEQIIEISIKAGIVGLAGVAIKNVADKMSSDELDHLITLSMMGNDEITEKYIISLQDKYGLHTGGNQLDGEFKLPQHTGRDPKVDSTLVLTHTGNDKPNADSITNTGNTDSKPDVGSSTTVTPLSEATSKDDLLYLSERVDNRLPIPEPIIASNGFKVESNTKHTPGAPGFRPNAGIELKNYMDLFEHSIATKDPKVRLSIDNDGNIHRFFNTSKDGTGTYHWSGSSGDGKNALGNRELGSFNKEIKELKGKG
>NZ_CP010947.1|WP_080891253.1|1265909_1266401_+|hypothetical-protein
MIFGQPFEFAVFYELLEKTDNGHWEFGIFIFFIEDEIYPSKGSNYTLSMAVNYLKDTHQEVIDSQDEGLDISITDHALLKLLAHSHGILLDCDPEDLDLPDSNKVGVFLSPPEVADAGFYLFYYLGSNESEFLIYSSDYGNTAKKTILNKGTVSRVLDELLYK
>NZ_CP010947.1|WP_044799387.1|1267054_1267825_+|LuxR-family-transcriptional-regulator
MNTLHALDLIGQFETAADERTIVTLLRELSGRMGFDYFRLALIFPSTIQRPDVIIFNGCPQAWVDTYTSSGFFAIDPIVKCAMTRSTPILWADVVKNEEHCDEQGREVMQLASEYGICDGITLPWHGANGHVGLLSFITSTPRTSQQWLSAVPFISWLSMHIFEAVARVCLAGLSPHDALSLRELEVCRWAAEGKQVSDIAQILGITPRTVTFHLNNVVSKLGASSKSQAISWALKQGMVRLNVEMALVANVDEKQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP010947_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_3

1378810-1378975

Orphan

Consensus_repeat	Method
GTCCTTGATATCCATCTGCTGCAGGGCGATGACCGCCTGGGGGCGGTTCTTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_3

>merge|NZ_CP010947|3|1378810-1378975|CRISPRCasFinder
GTCCTTGATATCCATCTGCTGCAGGGCGATGACCGCCTGGGGGCGGTTCTTGATGCCGAGTTTTCTGAAAGATGGGCGTGATGTGGGCCTTGATGGTGGCAAGAGGCTCAGTTGTCCTTGATATCCATCTGCTGCAGGGCGATGACCGCCTGGGTGCGGTTCTTGA

>NZ_CP010947|3|3|1378810-1378975|CRISPRCasFinder
GTCCTTGATATCCATCTGCTGCAGGGCGATGACCGCCTGGGGGCGGTTCTTGA	TGCCGAGTTTTCTGAAAGATGGGCGTGATGTGGGCCTTGATGGTGGCAAGAGGCTCAGTT
GTCCTTGATATCCATCTGCTGCAGGGCGATGACCGCCTGGGTGCGGTTCTTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_044799439.1\|1379719_1380346_+\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|198303
NZ_CP010947.1\|WP_044799440.1\|1380453_1382562_-\|alpha-amylase	unknown	unknown	gnl\|CDD\|236543
NZ_CP010947.1\|WP_044799433.1\|1366641_1368381_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP010947.1\|WP_005303379.1\|1383933_1384305_-\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|377229
NZ_CP010947.1\|WP_011705134.1\|1382770_1383934_-\|membrane-protein	unknown	unknown	gnl\|CDD\|227829
NZ_CP010947.1\|WP_016349890.1\|1368743_1369181_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374770
NZ_CP010947.1\|WP_044799442.1\|1387140_1388625_+\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|225536
NZ_CP010947.1\|WP_044799441.1\|1384301_1385360_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133030
NZ_CP010947.1\|WP_044799437.1\|1377189_1378059_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|378820
NZ_CP010947.1\|WP_044799436.1\|1375922_1377068_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132848
NZ_CP010947.1\|WP_044799435.1\|1371451_1372792_+\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|182626
NZ_CP010947.1\|WP_017408581.1\|1378130_1378712_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP010947.1\|WP_016349902.1\|1385416_1385962_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044799432.1\|1366018_1366558_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP010947.1\|WP_044799434.1\|1369292_1371323_-\|M13-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341056
NZ_CP010947.1\|WP_005303367.1\|1389413_1389665_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_029301559.1\|1388775_1389321_+\|DUF882-domain-containing-protein	unknown	unknown	gnl\|CDD\|283577
NZ_CP010947.1\|WP_139391831.1\|1372856_1373777_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NZ_CP010947.1\|WP_016349903.1\|1386288_1387059_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366132
NZ_CP010947.1\|WP_029301572.1\|1364697_1365978_+\|L-methionine/branched-chain-amino-acid-transporter	unknown	unknown	gnl\|CDD\|236823

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_044799439.1\|1379719_1380346_+\|glutathione-S-transferase	gnl\|CDD\|198303	cd03194, GST_C_3, C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 3; composed of uncharacterized proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain.	1.06124e-36
NZ_CP010947.1\|WP_044799440.1\|1380453_1382562_-\|alpha-amylase	gnl\|CDD\|236543	PRK09505, malS, alpha-amylase; Reviewed.	0
NZ_CP010947.1\|WP_044799433.1\|1366641_1368381_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	1.7715e-116
NZ_CP010947.1\|WP_005303379.1\|1383933_1384305_-\|GtrA-family-protein	gnl\|CDD\|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	7.48385e-12
NZ_CP010947.1\|WP_011705134.1\|1382770_1383934_-\|membrane-protein	gnl\|CDD\|227829	COG5542, COG5542, Predicted integral membrane protein [Function unknown].	0.00364418
NZ_CP010947.1\|WP_016349890.1\|1368743_1369181_-\|hypothetical-protein	gnl\|CDD\|374770	pfam16743, PliI, Periplasmic lysozyme inhibitor of I-type lysozyme.	8.47508e-61
NZ_CP010947.1\|WP_044799441.1\|1384301_1385360_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	3.29189e-90
NZ_CP010947.1\|WP_044799437.1\|1377189_1378059_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	2.82823e-12
NZ_CP010947.1\|WP_044799436.1\|1375922_1377068_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	4.53724e-42
NZ_CP010947.1\|WP_044799435.1\|1371451_1372792_+\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|182626	PRK10660, tilS, tRNA(Ile)-lysidine synthetase; Provisional.	4.36724e-152
NZ_CP010947.1\|WP_017408581.1\|1378130_1378712_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.08459e-10
NZ_CP010947.1\|WP_044799442.1\|1387140_1388625_+\|L,D-transpeptidase-family-protein	gnl\|CDD\|225536	COG2989, COG2989, Uncharacterized protein conserved in bacteria [Function unknown].	4.71242e-116
NZ_CP010947.1\|WP_044799432.1\|1366018_1366558_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	7.26267e-28
NZ_CP010947.1\|WP_044799434.1\|1369292_1371323_-\|M13-family-metallopeptidase	gnl\|CDD\|341056	cd08662, M13, Peptidase family M13 includes neprilysin and endothelin-converting enzyme I. The M13 family of metallopeptidases includes neprilysin (neutral endopeptidase, NEP, enkephalinase, CD10, CALLA, EC 3.4.24.11), endothelin-converting enzyme I (ECE-1, EC 3.4.24.71), erythrocyte surface antigen KELL (ECE-3), phosphate-regulating gene on the X chromosome (PHEX), soluble secreted endopeptidase (SEP), and damage-induced neuronal endopeptidase (DINE)/X-converting enzyme (XCE). Proteins in this family fulfill a broad range of physiological roles due to the greater variation in the active site's S2' subsite allowing substrate specificity. NEP is expressed in a variety of tissues including kidney and brain, and is involved in many physiological and pathological processes, including blood pressure and inflammatory response. It degrades a wide array of substrates such as substance P, enkephalins, cholecystokinin, neurotensin and somatostatin. It is an important enzyme in the regulation of amyloid-beta (Abeta) protein that forms amyloid plaques that are associated with Alzeimers disease (AD). ECE-1 catalyzes the final rate-limiting step in the biosynthesis of endothelins via post-translational conversion of the biologically inactive big endothelins. Like NEP, it also hydrolyzes bradykinin, substance P, neurotensin, and Abeta. Endothelin-1 overproduction has been implicated in various diseases including stroke, asthma, hypertension, and cardiac and renal failure. Kell is a homolog of NEP and constitutes a major antigen on human erythrocytes; it preferentially cleaves big endothelin-3 to produce bioactive endothelin-3, but is also known to cleave substance P and neurokinin A. PHEX forms a complex interaction with fibroblast growth factor 23 (FGF23) and matrix extracellular phosphoglycoprotein, causing bone mineralization. A loss-of-function mutation in PHEX disrupts this interaction leading to hypophosphatemic rickets; X-linked hypophosphatemic (XLH) rickets is the most common form of metabolic rickets. ECEL1 is a brain metalloprotease which plays a critical role in the nervous regulation of the respiratory system, while DINE is abundantly expressed in the hypothalamus and its expression responds to nerve injury. A majority of these M13 proteases are prime therapeutic targets for selective inhibition.	0
NZ_CP010947.1\|WP_029301559.1\|1388775_1389321_+\|DUF882-domain-containing-protein	gnl\|CDD\|283577	pfam05951, Peptidase_M15_2, Bacterial protein of unknown function (DUF882). This family consists of a series of hypothetical bacterial proteins of unknown function.	8.05542e-71
NZ_CP010947.1\|WP_139391831.1\|1372856_1373777_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.23212e-46
NZ_CP010947.1\|WP_016349903.1\|1386288_1387059_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|366132	pfam00497, SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.	2.03566e-28
NZ_CP010947.1\|WP_029301572.1\|1364697_1365978_+\|L-methionine/branched-chain-amino-acid-transporter	gnl\|CDD\|236823	PRK11021, PRK11021, putative transporter; Provisional.	0

>NZ_CP010947.1|WP_017408581.1|1378130_1378712_-|TetR/AcrR-family-transcriptional-regulator
MSKGRLTRDNILQTAFEQASQQGLESLTIGSLASACEMSKSGLFAHFQSRDNLQIAVLEYAAEVFRERVIQPVRQQQHGSQRAKLTALLQAWLAWNQCFAGRCMFLDAWTSAQEGEVQQAARQLVRFWLDYLARQVVQGQSEGEWRSDMDPWRAVYRLYGLYLADQVFNALDLCQDPARHFWPEVETLLDGWR
>NZ_CP010947.1|WP_044799437.1|1377189_1378059_-|alpha/beta-fold-hydrolase
MSSKIYFNTRRFSPSKWLLGLGTRLHHTLAPAHAKRTASKLLLTPQRNQRDDTAPAGLVKQAVHTSESTLMSYRLGQGPVWLLMHGWSGSAGQFYPLMSHIADQGFTAIAYDHPAHGHSAGHTGHLPRFVRAFDELVEKMTAEYGPLQGLIAHSMGGAVTLSSRRRELDALPLLLISPVLDYVPQLYGMVARSGYSIRLFDAVVKEIEQEYQHPLSTVDPLGRLAGRSGPAIIVHDEGDRFAPHGDSLRATQDGRTRLVSTRGLGHGRILTSAPAFAAFDQLSAVRRAN
>NZ_CP010947.1|WP_044799436.1|1375922_1377068_-|patatin-like-phospholipase-family-protein
MAKPNTALLLTGGGARAAYQVGALKAIAELYPRNLGIPFPILCGTSAGAINVTALACYASCFHLGVRKLEWVWRRFETHHIFDFHPGRLLWRLMYEGSAGLINPHTNHAFHLFDNAPLRRLLDQLIDYHRIDDNILYGSLEALAITASDYDDGLSTTFFQGRAEHLPWERARRRGLRTLLTSDHLLASSALPFVFPATHIGDKFYGDGSIHQLSPLSPAIHLGAERILLITLDPPAHTAPTFHHGHLTSSNIASHLLDTVFTDTLNSDLERLWRINQTLDLIPERERNRLKLKRVETCVLKPSQDLDLLALAYLRKLPVHLRRLLRVLGVTGDETSSLASFLMFYPGYCQQLIKLGYLDTLNERRRVEAFLGIEEMVPVEA
>NZ_CP010947.1|WP_139391831.1|1372856_1373777_-|GGDEF-domain-containing-protein
MFEGCTVENTSSLNGLGHGIEQWVRQMERLTPLASQDRNQLLELLLVQMDLGSLLATFADRAARIVRIHSLHFDCGQSHTLIQHPPQASLTLHSYPFELRGQHGQLIGQLHYTLEHALSGSQQRILQQYHQLLCLPLPLYLRLSQLELQVRLDHLTGLGNRSYFDEAIGRAVEQHSRESHGLVLVLLDLDNFKQINDTWGHPVGDLVLSRFAQLLTHCIRSTDQAFRLGGDEFALLLQPAEPEAWRPVWLRLQHMLLTHKELSTFSVGCSLGAASWQSGVDVHSLYEAADAHLYARKKAGKAGLLD
>NZ_CP010947.1|WP_044799435.1|1371451_1372792_+|tRNA-lysidine(34)-synthetase-TilS
MISRIYSRFCQTLPAPEGSRGLLVAFSGGLDSTVLLVLAARFARAHGLALRALHVHHGLSPNADEWVAHCETVCQQLAVPLLVERVQLQRDSGDSLEAQAREARYLRLAAQLGEGEWLLTAHHQDDQLETLLLALKRGAGLRGLAGMVPSQPFAGGLLLRPLLEVSRAELADAAASLPYGWVEDESNQDESYDRNFLRQRLIPQLKARWPAMAQTAARSMALCAEQEALLEDLAEADWRLAAAGEALQIAPLLALSGTRRNNLLRYWIRRQGGEMPSREQLGLLWQEVALAREDANPQLNWGGQSCRRFQGRLHLVRPGLLPRHEQLTLAVGETLSLPDGLGEVRLLPQVEGEGLRLPRADEPLSVRFGVAAGSMLKPVGRGGSRRLKKLLQEYGVPSWQRGRIPILYYGEQVAAVGELFLCDGFMTQGAGLAWHWLPVEACQPPL
>NZ_CP010947.1|WP_044799434.1|1369292_1371323_-|M13-family-metallopeptidase
MNNKKSILAALVGLALLAGCSQAPDGADKHSGLALANMDTSVKPGDDFFRYVNGHWLATAKIPDDRPADGAFYMLRDKSLADVRVLVEGLDGKAAAGTPAQQIHDLYQSYLDQTTRNAKGTAPLMPMLSEIEQIRTPQDLARAFAQSGRNGGGAPFGFWVDADAKAPDSYAVYLYQAGLGLPDRDYYLKTDAASQALRQKYEQHIATMLGRFGEADAGAKAKRILALESKLARIQWDNVTLRDREKNYNKGPQSELKRLAPAIDWNAYLTQADLAGQSSLIIGQPTYLAALNEVMQQTPVGDWQAYLKWHLITDFAPYLDSQTDAQNFAFFSTTLSGTPKQRAPWERALGVLDDHLGEAVGKLYVERYFPPQAKARMEQLVENLRTAYGQSIEELDWMSPATKAQAKEKLAKFRPKIGYPDKWKDYSAIAIRADDLVGNLQRARAFEYADNLARLGKPVDRDEWHMSPQTVNAYYNPSNNEIVFPAAILQPPFFDMTADDAVNYGAIGGVIGHEMGHGFDDQGAKSDGDGVMRDWWTPQDLKEFRFRTSRLVAQYNRFEPIKGQFVNGQFTLGENIGDLGGLTIAHKAYLLSLDGKEAPVLDGFTGEQRFFLGWAQVWKGMYRPELMQMLLASDPHSPPEYRVNGVVPNIPAFYEAFKIQPGDKLYLDPAKRVKIW
>NZ_CP010947.1|WP_016349890.1|1368743_1369181_-|hypothetical-protein
MKALLMTLGLLTLPLASQAADGFFKQLTLPSGQVVTVSEGRGEPASTGSYDVRLYSGANPQFPLDQFIDGKVLPRDGSIKELKLLDLNGDKQPELIVVVESAGSGSYLSADAFTINPQEGLDSFNHVEGLAPNEDVIQALKTPRD
>NZ_CP010947.1|WP_044799433.1|1366641_1368381_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MTTLMSTHSLQMSAGHLPLFDHLELGIRAGDRLGLVGANGCGKSTLLALLAGERAPQAGRVVQAAACRCEFVAQQLPARLSTLSTRAVLLDALGNDPSAEWQVDKLLAELQLEAQAALPVSALSGGQHSRLQIGRALLRQPNLLLLDEPSNHLDLPALLWLEQFLLGWRGAFVLVSHDGRLLDRVTEQTLILRDGQLHRFALPCSQARAALAAEDEQARLRRADEQKEIDRLSASSKRLAIWGREHDNEKLVRQAKSMEKRIARLQEQQSQVAALAPWRLELRGLSLPADTLLRLEALDVAPAPALPPLLRAEELWLRAGDRVALLGANGTGKSSLLRQCWRELAAQSPQAGWYCHPGASIAYYDQSLQQLADDATLCDALSPLAPLPEVTRRQALIRAGFPYARHGQQVHSLSGGERARLLFLALSLGSHHMLWLDEPTNHLDLAGKEQLAEAIAAFPGGVLLVSHDRELIERSCNRFWLIKDGRIQEAHSAERAYAELLGDAPSPAADKASLAAPAMGQAQAGPSNDEEALLARWYELDALLAADLARKPKHQTPRLQQQWRDELARLTDQLGLVGS
>NZ_CP010947.1|WP_044799432.1|1366018_1366558_-|GNAT-family-N-acetyltransferase
MTATQQPHIRLDPVSDADLPHIYRGLSDPRVVAYYGVSYDSLTACQAQMAWYAELTRTGRGAWHLIRDRHTGEPLGAIGYNDADPTHRRAELGYWLYPEHWGKGVMSAALRLWLPLTYRTSELHRLLAVVEEPNLPSARLLERTGFHYEGTARECERKGDGFISLRHYAILRSDLPANL
>NZ_CP010947.1|WP_029301572.1|1364697_1365978_+|L-methionine/branched-chain-amino-acid-transporter
MSGLKKDLGLWQGMGLLATSLLGTGIFVVPATAASLAGGASLWAWLLLIALVLPIAFTFARLGRRYPHAGGAPHLIGLAFGNGAERFSAFLFLAVLPVGLPAALMIAAGFWHALFDLGEWTLWGIQLLTLLGVFLLGLRGARSSGNLQLLIALAILGLTLLIWFKGDISWRDAARPLPTTDEWPAMATALAVMFWCFVGLEAFAHMGEEFKRPERDYPLALLGGVLLAGLIYWVHSLVVLKYGLYGDEATNATAIPALLSLLFGPTAKWLVAVLGYLSCFASINIYLQGFARLIWSMAREGKLPVSLARLTARGAPLRALSLVLAICLVCITLIIWLRLPLDELIRYANGNFVLVYLLCMAAGWRLLGGVGKGLAGVSVLLCALVLVALASQVLYAVVLSLGYGCFSLWRRRRRRSASDEGVCAIK
>NZ_CP010947.1|WP_044799439.1|1379719_1380346_+|glutathione-S-transferase
MGSLVLTVGTGSTWAMRAALVLAMSRLEWQEQVFDLEDAKELQRLKRLAPAGLVPWLDHDGVRIHDSLAIAEYLHELCPARRLYPEARAERALARSLCAELHAGFRQIRTLLPFFLGAPTRSEPPVEAIGELARLQTIWSQARGPFYFGEAGILDAFYAVMAYRLASYGIQLPGQAGAYQQALLAWPLWQQTLVKARLQWPAAAHQPQ
>NZ_CP010947.1|WP_044799440.1|1380453_1382562_-|alpha-amylase
MRRTPSVSSLWLALLASPLFLHQAMAAEVRLYVDDQPVGAPLALDKGAVQLTHPLTKGSHQIRISDAGNSCGTSFGPNEAKPLPFGTAQPMDKCSKGQHFNLRVMLAGDYQFTFNPDTPSLKVLRATKKSEFKRQPPVEPCISWDGGPVTVSLKGVWPDGTQLRDAYSGQQGVVKGGKLTLTPSKESGGLLLLEPVKAATAAPFSWDQASVYFLLTDRFNNGDPANDHSFGRQKDGQDEVATWHGGDFKGLTAKLDYIKQLGINAIWITPMVEQVHGFIGGGEQGNFPFYAYHGYWALDFTKIDPNYGDEESLKTLVDEAHKRGMRIILDVVMNHAGYATLADLQDLGLTDLTQNTGKLPARWNQWRPSGGLNWHGYNQFIDYQSPKWDQWWSGDWVRAGLPGYPQPGTDDVTGSVAGLPDFLTESTKPVGLPPLLAAKQDTRAKPLPNATVSDYLIAWHTDWVRRFGIDGFRADTVKHLEPEVWARLKQAGTAALKEWKAANPTKKLDDLPFYMVGEVWDHGVAKDFWYQNGFDSLINFDYQREFALPQAQCLASAEPTYAGYASRINQDPEFNVLSYISSHDTKLFFGDYQDVPLQRRVASSFMLLPGGIQIYYGDESGRGLAKDGGVFDQALRSDMNWQELAGGEKAELVKHWQRLGQFRAAHPAVAAGSHKKLADSPYAFVREKGDDKVVVVFAGRQP
>NZ_CP010947.1|WP_011705134.1|1382770_1383934_-|membrane-protein
MNDMTTSITPDNAGPYRPSLAISSRDWLMIIAAFVLSRAALYGMGYFGVQLYGSPDIGPLQAYCQFDCVWFQRIIENGYDLYPRWLSKGNAANWAFMPLYPMISGTISNLLNVESLIGLMLVANLAFFISLPLMLLVLRQLKLGDDTARFGVWLLAFSPFSAYFVSGYTESMFMALMLGMFLFAYRQQWLMVALLGVFISATRNLGVMMVFPVLILALQAYGWREFFRFTERAFKVVFTLWMIPLGLFAYMFYLYHLTGDALAFKHIQVAWGRYMDSPLDWWLSGFELGGRKSYLSIMVMFGWALNLYLFSQKRWAEATLMFICCTIPLMTGLNAMPRYMFGLYPTMLAIILLTHRWPAIRPAVLCLSGMVASFIAVAFVNFKFFTV
>NZ_CP010947.1|WP_005303379.1|1383933_1384305_-|GtrA-family-protein
MISREEFWRLVRFGFVGGGATLVDLGTSIALFHTWPTISEHLVTTLAFAIAFWFSFFGHRYITFQKQGAASKFLLVALFSLAVRNLILSGLLFAGLSGLLPVVIATLTVTVLTYLLSRIWVFA
>NZ_CP010947.1|WP_044799441.1|1384301_1385360_-|glycosyltransferase-family-2-protein
MSHADFRLSLIVPVYNEEESIDAFINAIDNELAPLKDQLEILFVNDGSRDRTREVVEQAIARDPRVTLVNLARNFGKEAAMTAGLHHAKGDAVVPMDVDLQDPPALILEFVKLWQTGDYDTVYGIRVDRSADTPMKRLTAGGFYRFFNALSTSTKLPENAGDFRLIDRKVVEAIKQLPERNRFMKGLFAWAGFRAVGVPYERPARHAGETKFNYWKLWNFALDGLMSFSSWPLRVWSYVGVGVSFVAFLYILKIVTQVVFFGIDVPGYASLMSVVLFLGGIQLLSLGIIGEYIGRMFVEVKQRPVYLIEGVYGQYAKQDEEPKQDATGSKKSASKKAAAAKAADDQQEQASQ
>NZ_CP010947.1|WP_016349902.1|1385416_1385962_-|hypothetical-protein
MTYKKFGFLTAIMALSGFYLYTLYLAAHPNVSLAYKLYYLEGKTRFWEHNSSMTYQPGNELNLTKPSRFLSSEGWAKKPSADGTELSGQGGLYFVLPKQQAQPEQLTIQARVNSPQAGALLKVALGHDFTTTVKLAKAGINEIRLSLPGESLTSDPKRPNFLALSAPTPLNVQSVRLTVAQ
>NZ_CP010947.1|WP_016349903.1|1386288_1387059_+|transporter-substrate-binding-domain-containing-protein
MKLKLCCWMLCLLAPLASANSLCPSPLRVGFDNWPPYHYYAGTAAGQKELRGFAVEALTAMLKRLDCKASYVEMPWKRVLHGLSLGSVDIAMEAYFNEDRARYAWFSDAYNPGRSALWIRKSSSYPETDLASWLASGHTLGITKDYYYGAEISELLRRYAAQVSVVNDEQNYGKLVLGRIDGFLGDVLATPWGLKEEGLSDLIVPHTMAVYEAPTFFMFSKKRLSPEFVSAFNRELAEFKATNEYDIIWRRYAPAS
>NZ_CP010947.1|WP_044799442.1|1387140_1388625_+|L,D-transpeptidase-family-protein
MGKKYWLALANLIWLGCWPAAMVQASEGQVVVSNAAMQHDWYQNSTAEQARRELELQLQEAVLAQLHPDFYTLWKKLQAKPADQRGALYDEAFGKLARFQQAWRAMDLVSREQMQTLKLNLSKPLAHEPAGDNLLEQVRQLRPQVAEYDAVREEVRKLLALPMAKKWPTLTMPTLRAGEVSPELGQIRSILNELGDTAPRHDDATYDAETLQAVKQFQRRHGLTADGIIGRQTRSWLNTGPEVRASLLLRNLWRRDLVDQLSGARYVLVNIPDYRLSVVESGNEVFTSRVIVGKEQRATPILASEIRSIVLNPAWHVPRSILSKDILPKLGRDPAYLNREQFEVIDGEGNPVQFTEEGWQQALASGFPFRLRQKPGDHNALGRYKFYLPNNEAIYLHSTPRKALFEQGARAFSSGCIRVEHADDLAELLLADSRYQPDKVASILKETQTKWLPLTTPIPVFTVYWSSWIDEDGRQQLRNDIYGFDRVSYQSRLL
>NZ_CP010947.1|WP_029301559.1|1388775_1389321_+|DUF882-domain-containing-protein
MLDQEISRRRLLLGAGCLLGGSLLSFPATASRSTAGRELSFFNLNTGERVRASYWEDGRYLKDGLAELNHIFRDYRRNEVFNIDRKLFDQLYLLQHKLGRHGEIQLISGYRSPVTNRQKRSRSRAVAKHSYHTLGQAVDVRIPGVQLAHLRKAALHLKVGGVGYYPSDNFVHLDTGPVRSW
>NZ_CP010947.1|WP_005303367.1|1389413_1389665_+|hypothetical-protein
MKHILLGGLIALLLTGCGKLNRENYDKLKMGISYAEASSILGKAERCDDALGTTSCIWGDEGKNIKIRFIADKATFFSSEGIN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP010947_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_4

1416871-1416952

Orphan

Consensus_repeat	Method
CGTGCCGTTTGTGAACAGGAGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_4

>merge|NZ_CP010947|4|1416871-1416952|CRISPRCasFinder
CGTGCCGTTTGTGAACAGGAGGCGTGATGAGGGAGTTATCCACATTTGCCGGCCCCATGCGTGCCGTTTGTGAGCAGGAGGC

>NZ_CP010947|4|4|1416871-1416952|CRISPRCasFinder
CGTGCCGTTTGTGAACAGGAGGC	GTGATGAGGGAGTTATCCACATTTGCCGGCCCCATG
CGTGCCGTTTGTGAGCAGGAGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_044799457.1\|1422385_1423681_+\|phosphate-regulon-sensor-histidine-kinase-PhoR	unknown	unknown	gnl\|CDD\|182895
NZ_CP010947.1\|WP_039216050.1\|1413270_1414170_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP010947.1\|WP_017408554.1\|1426605_1427508_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|183967
NZ_CP010947.1\|WP_044799448.1\|1405446_1406502_-\|HlyD-family-secretion-protein	unknown	unknown	gnl\|CDD\|224482
NZ_CP010947.1\|WP_044799453.1\|1416955_1418632_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225822
NZ_CP010947.1\|WP_011705170.1\|1424057_1425032_+\|phosphate-ABC-transporter-substrate-binding-protein-PstS-family-protein	unknown	unknown	gnl\|CDD\|273991
NZ_CP010947.1\|WP_010634735.1\|1406503_1406977_-\|transcriptional-regulator-SlyA	unknown	unknown	gnl\|CDD\|179596
NZ_CP010947.1\|WP_005298527.1\|1421687_1422377_+\|phosphate-regulon-transcriptional-regulatory-protein-PhoB	unknown	unknown	gnl\|CDD\|131209
NZ_CP010947.1\|WP_044799456.1\|1421174_1421585_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924
NZ_CP010947.1\|WP_039213362.1\|1408022_1409330_+\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP010947.1\|WP_044799455.1\|1419893_1421048_+\|CoA-transferase	unknown	unknown	gnl\|CDD\|367110
NZ_CP010947.1\|WP_044799450.1\|1410909_1412478_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP010947.1\|WP_073349272.1\|1407296_1407488_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044799449.1\|1409341_1410892_+\|NAD-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|237414
NZ_CP010947.1\|WP_044799454.1\|1418718_1419894_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173840
NZ_CP010947.1\|WP_044799451.1\|1414273_1415080_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380379
NZ_CP010947.1\|WP_044799458.1\|1425195_1426002_+\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|320690
NZ_CP010947.1\|WP_011705161.1\|1412481_1413174_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP010947.1\|WP_044799452.1\|1415142_1416660_-\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143434
NZ_CP010947.1\|WP_044799459.1\|1425989_1426496_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_044799457.1\|1422385_1423681_+\|phosphate-regulon-sensor-histidine-kinase-PhoR	gnl\|CDD\|182895	PRK11006, phoR, phosphate regulon sensor histidine kinase PhoR.	0
NZ_CP010947.1\|WP_039216050.1\|1413270_1414170_-\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	3.76896e-19
NZ_CP010947.1\|WP_017408554.1\|1426605_1427508_+\|ROK-family-protein	gnl\|CDD\|183967	PRK13310, PRK13310, N-acetyl-D-glucosamine kinase; Provisional.	3.13853e-109
NZ_CP010947.1\|WP_044799448.1\|1405446_1406502_-\|HlyD-family-secretion-protein	gnl\|CDD\|224482	COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms].	2.0883e-65
NZ_CP010947.1\|WP_011705170.1\|1424057_1425032_+\|phosphate-ABC-transporter-substrate-binding-protein-PstS-family-protein	gnl\|CDD\|273991	TIGR02136, ptsS_2, phosphate binding protein. Members of this family are phosphate-binding proteins. Most are found in phosphate ABC-transporter operons, but some are found in phosphate regulatory operons. This model separates members of the current family from the phosphate ABC transporter phosphate binding protein described by TIGRFAMs model TIGR00975. [Transport and binding proteins, Anions].	2.20214e-86
NZ_CP010947.1\|WP_010634735.1\|1406503_1406977_-\|transcriptional-regulator-SlyA	gnl\|CDD\|179596	PRK03573, PRK03573, transcriptional regulator SlyA; Provisional.	1.05279e-33
NZ_CP010947.1\|WP_005298527.1\|1421687_1422377_+\|phosphate-regulon-transcriptional-regulatory-protein-PhoB	gnl\|CDD\|131209	TIGR02154, PhoB, phosphate regulon transcriptional regulatory protein PhoB. PhoB is a DNA-binding response regulator protein acting with PhoR in a 2-component system responding to phosphate ion. PhoB acts as a positive regulator of gene expression for phosphate-related genes such as phoA, phoS, phoE and ugpAB as well as itself. It is often found proximal to genes for the high-affinity phosphate ABC transporter (pstSCAB; GenProp0190) and presumably regulates these as well. [Regulatory functions, DNA interactions, Signal transduction, Two-component systems].	1.37954e-135
NZ_CP010947.1\|WP_044799456.1\|1421174_1421585_+\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.87122e-36
NZ_CP010947.1\|WP_039213362.1\|1408022_1409330_+\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	1.9277e-159
NZ_CP010947.1\|WP_044799455.1\|1419893_1421048_+\|CoA-transferase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	2.95812e-159
NZ_CP010947.1\|WP_044799450.1\|1410909_1412478_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	4.52699e-113
NZ_CP010947.1\|WP_044799453.1\|1416955_1418632_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	3.25983e-124
NZ_CP010947.1\|WP_044799449.1\|1409341_1410892_+\|NAD-dependent-malic-enzyme	gnl\|CDD\|237414	PRK13529, PRK13529, oxaloacetate-decarboxylating malate dehydrogenase.	0
NZ_CP010947.1\|WP_044799454.1\|1418718_1419894_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173840	cd01151, GCD, Glutaryl-CoA dehydrogenase. Glutaryl-CoA dehydrogenase (GCD). GCD is an acyl-CoA dehydrogenase, which catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and carbon dioxide in the catabolism of lysine, hydroxylysine, and tryptophan. It uses electron transfer flavoprotein (ETF) as an electron acceptor. GCD is a homotetramer. GCD deficiency leads to a severe neurological disorder in humans.	0
NZ_CP010947.1\|WP_044799451.1\|1414273_1415080_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|380379	cd06124, cupin_NimR-like_N, AraC/XylS family transcriptional regulators similar to NimR, N-terminal cupin domain. This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is Escherichia coli HTH-type transcriptional regulator NimR (also called YeaM) that negatively regulates expression of the nimT operon and its own expression. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	6.34791e-27
NZ_CP010947.1\|WP_044799458.1\|1425195_1426002_+\|M48-family-metallopeptidase	gnl\|CDD\|320690	cd07331, M48C_Oma1_like, Peptidase M48C, integral membrane endopeptidase. This subfamily contains peptidase M48C Oma1 (also called mitochondrial metalloendopeptidase OMA1) protease homologs that are mostly uncharacterized. Oma1 is part of the quality control system in the inner membrane of mitochondria, with its catalytic site facing the matrix space. It cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins. Oma1 can cleave the misfolded multi-pass membrane protein Oxa1, thus exerting a function similar to the ATP-dependent m-AAA protease for quality control of inner membrane proteins; it cleaves a misfolded polytopic membrane protein at multiple sites. It has been proposed that in the absence of m-AAA protease, proteolysis of Oxa1 is mediated by Oma1 in an ATP-independent manner. Oma1 is part of highly conserved mitochondrial metallopeptidases, with homologs present in higher eukaryotes, eubacteria and archaebacteria, all containing the zinc binding motif (HEXXH). It forms a high molecular mass complex in the inner membrane, possibly a homo-hexamer.	1.80141e-86
NZ_CP010947.1\|WP_011705161.1\|1412481_1413174_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.67073e-63
NZ_CP010947.1\|WP_044799452.1\|1415142_1416660_-\|aldehyde-dehydrogenase	gnl\|CDD\|143434	cd07116, ALDH_ACDHII-AcoD, Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like. Included in this CD is the NAD+-dependent, acetaldehyde dehydrogenase II (AcDHII, AcoD, EC=1.2.1.3) from Ralstonia (Alcaligenes) eutrophus H16 involved in the catabolism of acetoin and ethanol, and similar proteins, such as, the dimeric dihydrolipoamide dehydrogenase of the acetoin dehydrogenase enzyme system of Klebsiella pneumonia. Also included are sequences similar to the NAD+-dependent chloroacetaldehyde dehydrogenases (AldA and AldB) of Xanthobacter autotrophicus GJ10 which are involved in the degradation of 1,2-dichloroethane. These proteins apparently require RpoN factors for expression.	0
NZ_CP010947.1\|WP_044799459.1\|1425989_1426496_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.22645e-12

>NZ_CP010947.1|WP_044799452.1|1415142_1416660_-|aldehyde-dehydrogenase
MIYTAPGQAGALVSFKSRYDNFIGGEWVAPRAGRYFENISPVDGKVFCEVARSDAADIELALDAAHKAFTSWSKTSVTERSNLLLRIADRIEQNIEVLAIAETWENGKAVRETLAADLPLVVDHFRYFAGCIRAQEGSAAELDQNTVSYHFKEPIGVVGQIIPWNFPLLMAAWKLAPVLAAGCCSVLKPAEQTPVTIMLMMDLIKDILPAGVVNVVNGFGAEAGQALATSNRIQKLAFTGSTEVGAHILRCAADKLIPSTVELGGKSPNIYFADVMQHESSYIDKAVEGMLMTFFNQGEVCTCPSRALVQASIYDDFMDKVLARARTIVQGNPLDTATQVGAQASREQFDKILSYMEIGRGEGAKMLIGGGPARVSGLEGGFYIQPTIFSGQNKMRVFQEEIFGPALGVTTFKDEADALAIANDTQYGLGAGLWTRDSNLAWRMGRGIQAGRVWVNCYHAYPAHAAFGGYKKSGIGRETHKMMLDHYQNTKNLLVSHDINPLGFF
>NZ_CP010947.1|WP_044799451.1|1414273_1415080_+|AraC-family-transcriptional-regulator
MAIRHYHPTDLHLPEPNPLYLRYQQIQAESACAPHSHPWGQLSLISLGVMEIVLDDHRLVAPADYLIWVPADLEHASYNQQALDYTSIYVNHALAARLPAEPRLLQMTPLIRAILADFCDRKLGHMADEWDVRQAELLVEKLTRTRCQDSYLPMSQDKLLAPMLAALYSDPADPRTLAQWAEQLHTTERTLARRCVRELGMNFGQWRARLKLLKALAWLKGELPVQEIGWRLGYGSTSAFIAMFNRELGCSPQRYRQQLGIGAGQAAL
>NZ_CP010947.1|WP_039216050.1|1413270_1414170_-|DMT-family-transporter
MRIFYPLMFPLLAVLIWATNTVVSKAAADVLDPAAISFYRWVIAALALTPFCLPQLWRRRGEIRPWLGKLLVLAALGMVLYQCLAYYAAHTTSATNMGVIGSLIPLLTLLQSALFFGQRPGKQALLGMSISLFGVFWLLSLGQPLALLHDGINQGDGLMLLGSASYALYGLLIRRWQLPFGPWLNLYLQILLAVLLLIPVALCAESLAVPAEGWGLVLFAGIASSLFAAYCWMRGLACMGAERTSVFMNLMPLCTALIAVISLGEPIHGYHLLGGGLILAGVMLSQFKPKARPALLEEA
>NZ_CP010947.1|WP_011705161.1|1412481_1413174_+|response-regulator
MEPIFTLVIEDDERIGSILAELVSSTPGFSLLGRAESLTQADLMMRAAQPQLLLVDISLPDGSGLEWVNRLRSHNREAYVIMVTASCDVETIQQALNQGVQDYIIKPLRLFRIQQSLDEILTLHRRICERGSLEQSDLDRLMGKVRPQGREVRDTPKGIDAITLRQVLELLAGEPDSAFSTDTVALRLSLSRTTARRYLEYLESEDRVDVDLNYGQRGRPERRYHWRRGS
>NZ_CP010947.1|WP_044799450.1|1410909_1412478_+|sensor-histidine-kinase
MKLRHQLVTLSLGLSLLLIVILGSLLALFIRHLLEVNLEEKGGDLARVLAADQRVVQALEWGSDPGLRDYVQGICSRTDAAYMVVTDEHARRLSHPSPELVGGLFRGEDIWPSLNERSSYCSKDVGTLGPAIRCFAPVIGADGRAIGAVVVGYLMQTVEGIYLDRIALLISAIGAVLGCGLLLALWIQHRLRRTLLDLEPETIVNRFVLQELVLEHISEGVIALDSQGHIRMLNSAAFYQLRLPGTGRHSLLGQPLAELSPPLAPALTQLETELGFTVHGESFIGRWQAVEGKIPGRLLIFSRPEVTGSLGMQVTHLRQYAEMLRMQTHEFANKLSSLSGLLQLGHVEQAVELIQQESEACQTMLHDLLRAIEDKPVAGLILGKFSRARELGVELVLDPDSALGEYPAAVSADLITLIGNLLDNGIRAAWARRKQCPPRVLISLNDFGRRLVIEVEDSGEGVDEALADHLFDYGISRQTGDHGVGLFLVKETVARRGGVIEWRRTAEQTTLFGIYLNKNQLV
>NZ_CP010947.1|WP_044799449.1|1409341_1410892_+|NAD-dependent-malic-enzyme
MNDIMMGTSLPYAERKRQGLMGRMPHKEESLAQQRRRIYRLVSAMQSPFDQHLLLRQLQEDNPVLFYELVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDRDELDDIFAAVEQEVDVIVISDGERVLGLGDLGIGGMGICIGKLALYSAAGGINPARTLPLCVDVGTNNPELLEDDSYLGWQAPRVDGEPYYQFMDKVVAAIRKRWPQVVLQFEDFAGKHAANLLARYRDELCMFNDDIQGTAAVASACVLAGLQQAGSALAETPVLIVGAGSAGCGIAAMLAQLAGSTERVQLFDQDGLVCQDRAGLTPAQQPFARPAAEACNSLSALIERLRPGVLIGVSGQGGLFDEAVLTAMGEVCERPVILPLSNPTRSAEATPAQVWQATGGRALLATGSPFPPVAVDGAPRVVSQCNNVYVFPGIGLGACAVKARRISDGMLRAAVQAVGAYPLAEGRLLPPIEQVGEVARTVARAVALCARAEGLADFAGDPAPLIDQTWWRPHYWSAS
>NZ_CP010947.1|WP_039213362.1|1408022_1409330_+|2-hydroxycarboxylate-transporter-family-protein
MKNLSTPQTRIALFGDRQIAGMPMMIFLGLATCVLFSGWNGSLPLGMVGALALMFVLGTLLTELGERITPIREYLGGGTILAIFGGAALFEYRILPVEAGQVIIGFMKEGGFLNFFIASLVTGSVFGMSGALLKNAAMRYLPVILGGVALALLSVGLVGALMGYGFKNAVLLIGLPIMGGGMGAGAVPLVEILSGPLQMSSADLLSRMVPAVVIANTLAILVGTLLARLGRRYPSLTGNGKLMIKESAAGVAEEKVQAPTLESLGLGLFISSSMFVLGSLLGNFIPMHPFALMILAVAVIKVSGLLPRRYEQAAADWYQFVVSNLTPSLLVGIGVAYTSIPELISAFSVSYFVLVLVTVVGGALGAALVGRMIGFYPIEAAITGGLCMANMGGTGDVAVLSAAQRMTLMPFAQISSRLGGAVMLILATLLISLLA
>NZ_CP010947.1|WP_073349272.1|1407296_1407488_+|hypothetical-protein
MMGQLNRETIAVERYESGDPHFSIESLLVEVEYVADGHYGLSLESTETCHEFDPANIPLLLAE
>NZ_CP010947.1|WP_010634735.1|1406503_1406977_-|transcriptional-regulator-SlyA
MMKDLEMLRELSLAERVGRLHRLWRTVADLELAPLGLTHPRWTALWKLSRLGGHLSQKTLAEALEIELPSLMRTLGQLEEQGLVERHCCSQDKRARIVTLTPAGKALLDQIEDRIMEIRRELLAGISQRELEQFEDIVHRICANALGKIGAQSEERE
>NZ_CP010947.1|WP_044799448.1|1405446_1406502_-|HlyD-family-secretion-protein
MTPDQQFKRWIKWAMGAFVLVFAYFLLADLKMPLTPQAMATRVVTKMAPQVSGKVVEVAVGNNQHVKQGDLLFVLDPAPFELAVEQARLALAQAEQQNRQLDATLNAASADFSSLQTQAALKLREAERIDALYRRHMVSEQQKDDADSAFRTAQANLLASKARMTQARVNRGLPGDDNLLLRQARNRLAQAELNLAYSRVHASQDGIITNLQLKPGSFAAAGAPLLALVSEQVDVIADFREKSLRHVNQDSQALVAFDGEPGRLYPARVTSLDAGVSAGQFDANGLLASPTESDRWVRDAQRLRLHLALEQLPAHLPAGARATVQLLPDNSLTGLLARAQIRLLSLLHYIY
>NZ_CP010947.1|WP_044799453.1|1416955_1418632_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MSELSQSSASPIERSWQRCLHQGLSRRQSAELDLLPQGELSARQEQHRVLIASFQRFVLPLFGQLLAGRPCRLLLCDGEGAILAASGDDGFARHAERIFLRSGARWGEASKGTNAIGTALAEQSEVQVLGNQHFFAQHSFLSCSACPLLGPDGQLLGVLDISTDAAHHDGDMLGTVRLLAMTLENALLARQPGWLVDLDPQSLWSARLLLGEEGELLGANRAGRLWLGQHPFDGKQLLRDRRGLRLVPEAHPVATLPGLPADAGGSHGRQVPLKMLERGISLLIEGETGSGKEHLVRELHGQSSRRAQPLVCVNCGALPADLVEAELFGYVGGAFSGARSQGSQGYLRAAHGGILMLDEIGELPLLAQTRLLRVLQERAVTPVGSHKPEAVDFWLVSASHRDLAAMVAAGTFREDLYYRICGWRQLLVPLRDWPTRERQALVRRLLAEMDPALHLTDEAECHLLAHPLPGNVRQLKQALEVACVLAEGQGWIEPAHLHLPTVAVAPLITTAVAGSTLRQQNRQRVQQTLTECDGNVSEAARRLGISRTTLYRALREAG
>NZ_CP010947.1|WP_044799454.1|1418718_1419894_+|acyl-CoA-dehydrogenase
MTRTRFDWQDPFFLDGQLSEEERLIRDAARDYCQARLMPRVLEANRREQFDRTIMNELGELGLLGATLPEQYGCAGVNHVAYGLIAREVERVDSGYRSAMSVQSSLVMHPIHAYGDEAQRQRWLPGLARGELVGCFGLTEPDAGSDPGSMKSRAERVDGGYLLTGNKMWITNSPIADLFVVWAKLDGEITGFVLEKGMAGLSAPKIEGKFSLRASITGEIVMERIFVPEANRLAGVSGLKGPFGCLNKARYGIAWGALGAAEFCWHAARQYGLDRQQFGRPLAATQLFQLKLANMQTEIALGLQGCLQAGRLMDEGRCPVELVSLIKRNSCGKALEIARVARDMHGGNGISDEFHVIRHVMNLESVNTYEGTHDIHALILGRAQTDLQAFE
>NZ_CP010947.1|WP_044799455.1|1419893_1421048_+|CoA-transferase
MGPLAGVRVLDLSRVLAGPWASQLLADLGADVVKVETPGRGDDTRHWGPPELVAGEAAYFHAANRGKRSIALDLARDRETLLALVDRADVVIENFKVGGLARYGLDYPSLKARRPELIYCSITGFGQDGPWAQRPGYDLLIQGLGGLMSITGQPDEAPGGGPVKVGVALVDILTGLYATIGIQAALRHRERTGEGQQIDLALLDVSVAVLANQAMNYLATGQTPGRLGNGHPNIVPYDVYPTRDGHLILAVGNDGQFAALAALLGEPGWATDSDFASNSARVRQRHRLNALIAERLLARSSAEWSAMLEAAGVPGGPILTLDALFALEQGAVRGWVQQVQRGEQPLPTLANPLHLSATPVRYGRASPVLDGDRDSVLRDWLGQG
>NZ_CP010947.1|WP_044799456.1|1421174_1421585_+|VOC-family-protein
MAQHIGALALLVADYDQAIAFFTQGLGFELLEDTPLDEPGKPGKRWVRVAPKGTPGSALLLARAATPEQRAAIGQQGGGRVFLFLETDDFWGDYQRMQAYGVHFCEQPRSEAYGTVVVFEDISGNRWDLLQLAAAN
>NZ_CP010947.1|WP_005298527.1|1421687_1422377_+|phosphate-regulon-transcriptional-regulatory-protein-PhoB
MAKRILVVEDEAPIREMLCFVLEQKGYETVEAEDFADGLAKVREPYPELIVLDWMMPGGSGIQFIKQLKQDEVTRQIPVVMLTARGEEEDKVRGLEAGADDYITKPFSPKELTARLHAVMRRVSPTSVDEVIEVQGLKLDPVSHRVSAEEKALDMGPTEFKLLHFFMTHPERVYSREQLLNNVWGTNVYVEDRTVDVHIRRLRKAIEETGHDRLIQTVRGAGYRFSTRL
>NZ_CP010947.1|WP_044799457.1|1422385_1423681_+|phosphate-regulon-sensor-histidine-kinase-PhoR
MLQPYAWRRQLWRIAFFYAPFALVGWLTNTLALCLLAATVLHLGWHYRFQKRLSDWLWHDRSLVPPNGSGSWEYIFNGIYKLQQRHRARRRELAGLIRRFREGAEALPDAAVVFRTDGSILWCNRLAEQLLGFRWPEDAGQHIGNLIRNPAFGAYLGKGQYDEPFEMTSPINEEKFLEFRIMPYAEDQAMLVVRDVTRLRSLEKTRKHFVSNVSHELRTPLTVLKGYLEMTEEPPPPAMWAKAHKVMMEQTIRMDNLVNQLLTLSRIEAAPTVDLSHLVDMPAMLGLLEQEARALSGERAHQIEFMVQPNLLVRGDQDQLRSAVSNLVYNAIHYTPAGRKITVEWRKQGAMALFAVQDEGEGIPPEHLARLTERFYRVDKARSRHTGGSGLGLAIVKHALSHHDCQLDIESRVGLGSRFSFLIPGRMVVVK
>NZ_CP010947.1|WP_011705170.1|1424057_1425032_+|phosphate-ABC-transporter-substrate-binding-protein-PstS-family-protein
MKLNKLAGVIGFTAATLFSVSTLAAGVDKNLPDYTPTSGISGNLSSVGSDTLANMMTLWAEEFKRMYPNVNVQIQAAGSSTAPTALTEGVAQFGPMSRAMKSGEEEAFEKRYGYKPTAIRVAVDALAVFVNKDNPIKGLTMPQLDAIFSSTLKCGEAKAATKWADLGLDGNWSSKDLQLFGRNSVSGTYGYFKEHALCNGDFKSGVNEQPGSASVVQSVSSSLNGIGYSGIGYVTSGVRAVPLSKDGKTFIEATSDNAITGKYPLSRFLYVYVNKHPNKPLSPMEQEFLKMVLSKAGQNIVAKDGYVPVPAKVVEADLKKLGIM
>NZ_CP010947.1|WP_044799458.1|1425195_1426002_+|M48-family-metallopeptidase
MTSPLFKLGLAALCSTLLASCAQSPTGRSQMLLFSPQQMSKLGADSFEEMKKQEKVSTDAKMNAYVSCVAKAVTAQVPSQYGITSWEVVVFDSKQVNAFALPGGKIGVYSGLLKVAKNQDQLATVIGHELTHVLAQHSNERLSRSQLTGLGLAAADIAMGSSEYRGATMAALGLGVEVGVMLPYGREQESEADRLGLDLMARAGFNPAEAIPLWQNMSAAAGGNVPPQLLSTHPSNENRIAELQAQQAEAVPLYEQARASGLVPQCKA
>NZ_CP010947.1|WP_044799459.1|1425989_1426496_+|GNAT-family-N-acetyltransferase
MQGISLRMARPDDAAAMTVMQRASWLAAYGGVLGADMLAQLAVTEHLQIWQRRLAETGPRPMLLCQDEVVIGLLYWQPETTGEYPTAWIRAFYLHPDHWRQGHGKRLWQAVAIQMRRAGCEGVRLWLLDGNHIGEGFYLRRGFMFDGQERTLMSLGQPCLQRQMFRLL
>NZ_CP010947.1|WP_017408554.1|1426605_1427508_+|ROK-family-protein
MYYGFDIGGTKIAFAVYDGALNLCHEERMSTPGNDYEGLQQLIRARVEQADARFGARGAVGIGFPGILNRHDHSIVAANLPSINGRHLGADLAELLERPVKVDNDANCFLWSEVHQGAAAGADSALGVTIGTGIGGAVYLAGKLIQGRNWLAGEIGHYPLPATMLMKYPDLPRPRCGCGRLVCFETYASGTGLERLYHHFHGQRASGHQIVGRFEAHEPHAVATVDCWLEIMAAGLATAISVVDPDVVVLGGGLSGLPALYEQLPLRLPGHLLPGVALPEIREARFGGAGGVRGAALLNL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP010947_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_5

1453399-1453509

Orphan

Consensus_repeat	Method
AGGTCAGTGGCAGCAGAGCCTGCAGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_5

>merge|NZ_CP010947|5|1453399-1453509|CRISPRCasFinder
AGGTCAGTGGCAGCAGAGCCTGCAGCCTGACTTTCATGCAAATGGCTCCGGTCCAAACATAGTTGGCGGTACAGTCAGTGCGGCAGGTCAGTGGCAACAGAGCCTGCAGCC

>NZ_CP010947|5|5|1453399-1453509|CRISPRCasFinder
AGGTCAGTGGCAGCAGAGCCTGCAGCC	TGACTTTCATGCAAATGGCTCCGGTCCAAACATAGTTGGCGGTACAGTCAGTGCGGC
AGGTCAGTGGCAACAGAGCCTGCAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_044799470.1\|1441985_1443356_+\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NZ_CP010947.1\|WP_044799475.1\|1464521_1465901_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240539
NZ_CP010947.1\|WP_016349932.1\|1436724_1437228_+\|NUDIX-hydrolase-YfcD	unknown	unknown	gnl\|CDD\|185291
NZ_CP010947.1\|WP_029301530.1\|1437290_1438217_-\|phenylacetate--CoA-ligase	unknown	unknown	gnl\|CDD\|341239
NZ_CP010947.1\|WP_024944726.1\|1466021_1466879_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP010947.1\|WP_044799468.1\|1438343_1438817_+\|redoxin-family-protein	unknown	unknown	gnl\|CDD\|223750
NZ_CP010947.1\|WP_144406120.1\|1459297_1459504_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_005298586.1\|1464122_1464371_-\|YciN-family-protein	unknown	unknown	gnl\|CDD\|182919
NZ_CP010947.1\|WP_044799467.1\|1435463_1436210_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP010947.1\|WP_044799474.1\|1461315_1462713_-\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP010947.1\|WP_144406117.1\|1457109_1457457_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044799473.1\|1460517_1461216_-\|protein-ligase	unknown	unknown	gnl\|CDD\|319742
NZ_CP010947.1\|WP_052508931.1\|1457615_1459301_+\|DUF637-domain-containing-protein	unknown	unknown	gnl\|CDD\|377410
NZ_CP010947.1\|WP_044799476.1\|1466947_1468642_+\|NAD-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|237414
NZ_CP010947.1\|WP_011705188.1\|1462958_1464098_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NZ_CP010947.1\|WP_011705184.1\|1439975_1441127_-\|type-III-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|143482
NZ_CP010947.1\|WP_016349931.1\|1436320_1436536_-\|DUF1107-domain-containing-protein	unknown	unknown	gnl\|CDD\|368954
NZ_CP010947.1\|WP_052508930.1\|1445307_1446975_+\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|368641
NZ_CP010947.1\|WP_158319748.1\|1443854_1445294_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP010947.1\|WP_044799469.1\|1438941_1439910_+\|calcium/sodium-antiporter	unknown	unknown	gnl\|CDD\|182684

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_044799470.1\|1441985_1443356_+\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NZ_CP010947.1\|WP_044799475.1\|1464521_1465901_-\|MATE-family-efflux-transporter	gnl\|CDD\|240539	cd13134, MATE_like_8, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.36514e-98
NZ_CP010947.1\|WP_016349932.1\|1436724_1437228_+\|NUDIX-hydrolase-YfcD	gnl\|CDD\|185291	PRK15393, PRK15393, NUDIX hydrolase YfcD; Provisional.	8.18976e-101
NZ_CP010947.1\|WP_029301530.1\|1437290_1438217_-\|phenylacetate--CoA-ligase	gnl\|CDD\|341239	cd05913, PaaK, Phenylacetate-CoA ligase (also known as PaaK). PaaK catalyzes the first step in the aromatic degradation pathway, by converting phenylacetic acid (PA) into phenylacetyl-CoA (PA-CoA). Phenylacetate-CoA ligase has been found in proteobacteria as well as gram positive prokaryotes. The enzyme is specifically induced after aerobic growth in a chemically defined medium containing PA or phenylalanine (Phe) as the sole carbon source. PaaKs are members of the adenylate-forming enzyme (AFE) family. However, sequence comparison reveals divergent features of PaaK with respect to the superfamily, including a novel N-terminal sequence.	5.0071e-30
NZ_CP010947.1\|WP_024944726.1\|1466021_1466879_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	5.38229e-28
NZ_CP010947.1\|WP_044799468.1\|1438343_1438817_+\|redoxin-family-protein	gnl\|CDD\|223750	COG0678, AHP1, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.67368e-66
NZ_CP010947.1\|WP_005298586.1\|1464122_1464371_-\|YciN-family-protein	gnl\|CDD\|182919	PRK11037, PRK11037, hypothetical protein; Provisional.	3.67973e-46
NZ_CP010947.1\|WP_044799467.1\|1435463_1436210_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.34365e-161
NZ_CP010947.1\|WP_044799474.1\|1461315_1462713_-\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	6.53234e-149
NZ_CP010947.1\|WP_044799473.1\|1460517_1461216_-\|protein-ligase	gnl\|CDD\|319742	cd16443, LplA, lipoate-protein ligase. Lipoate-protein ligase A (LplA) catalyzes the formation of an amide linkage between free lipoic acid and a specific lysine residue of the lipoyl domain in lipoate dependent enzymes, similar to the biotinylation reaction mediated by biotinyl protein ligase (BPL). The two step reaction includes activation of exogenously supplied lipoic acid at the expense of ATP to lipoyl-AMP and then transfer to the epsilon-amino group of a specific lysine residue of the lipoyl domain of the target protein.	5.23923e-32
NZ_CP010947.1\|WP_052508931.1\|1457615_1459301_+\|DUF637-domain-containing-protein	gnl\|CDD\|377410	pfam04830, DUF637, Possible hemagglutinin (DUF637). This family represents a conserved region found in a bacterial protein which may be a hemagglutinin or hemolysin.	4.43238e-29
NZ_CP010947.1\|WP_044799476.1\|1466947_1468642_+\|NAD-dependent-malic-enzyme	gnl\|CDD\|237414	PRK13529, PRK13529, oxaloacetate-decarboxylating malate dehydrogenase.	0
NZ_CP010947.1\|WP_011705188.1\|1462958_1464098_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.06979e-60
NZ_CP010947.1\|WP_011705184.1\|1439975_1441127_-\|type-III-PLP-dependent-enzyme	gnl\|CDD\|143482	cd00622, PLPDE_III_ODC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase. This subfamily is composed mainly of eukaryotic ornithine decarboxylases (ODC, EC 4.1.1.17) and ODC-like enzymes from prokaryotes represented by Vibrio vulnificus LysineOrnithine decarboxylase. These are fold type III PLP-dependent enzymes that differ from most bacterial ODCs which are fold type I PLP-dependent enzymes. ODC participates in the formation of putrescine by catalyzing the decarboxylation of ornithine, the first step in polyamine biosynthesis. Members of this subfamily contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain, similar to bacterial alanine racemases. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Homodimer formation and the presence of the PLP cofactor are required for catalytic activity. Also members of this subfamily are proteins with homology to ODC but do not possess any catalytic activity, the Antizyme inhibitor (AZI) and ODC-paralogue (ODC-p). AZI binds to the regulatory protein Antizyme with a higher affinity than ODC and prevents ODC degradation. ODC-p is a novel ODC-like protein, present only in mammals, that is specifically exressed in the brain and testes. ODC-p may function as a tissue-specific antizyme inhibitory protein.	1.45333e-159
NZ_CP010947.1\|WP_016349931.1\|1436320_1436536_-\|DUF1107-domain-containing-protein	gnl\|CDD\|368954	pfam06526, DUF1107, Protein of unknown function (DUF1107). This family consists of several short, hypothetical bacterial proteins of unknown function.	9.77419e-24
NZ_CP010947.1\|WP_052508930.1\|1445307_1446975_+\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|368641	pfam05860, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	2.60043e-31
NZ_CP010947.1\|WP_158319748.1\|1443854_1445294_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	9.4013e-105
NZ_CP010947.1\|WP_044799469.1\|1438941_1439910_+\|calcium/sodium-antiporter	gnl\|CDD\|182684	PRK10734, PRK10734, putative calcium/sodium:proton antiporter; Provisional.	3.12331e-86

>NZ_CP010947.1|WP_052508930.1|1445307_1446975_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MSTPKLPLTLRLLAYHLSALLALQPAHPAFAEGIAVATGSTTLNQAGNGVPVVDIATPNGAGVSHNLYQDFNVAQPGVILNNTTGQLTQTQLGGLIQNNPHLTGAPANVIINEVVGANPSQLQGYLEVAGQQAGVVVANPNGLTCDGCGFINTPNVTLSTGKPVLDAHGQLQMLDVKQGALTVGGKGLDGSRQASVDLIARAVQLNGALHGKEVNVIAGANTVNRQTGEIRAQQGDGTVPEVAIDTAAMGGMYAGKIRLVSTEQGVGVNLANAVATQGDLTLDANGKIRLRDSSSAGNLQVSSQGELAVTGAIHSGGAAKLAAGGELTAQDADIAAKGDATLQARAQQLQRTKVSSGGTLALQANDALVVREGELQGETLHATAQQLDTQSALTAKDVTLQAEQLRQAGHVQGTSVRLTAGVLRHEGTTQAAQNLTIDATTLDNQGTLKSGQAMSVALGERGHNAGELSAGDNLTIRAGTRWEQGEQGKSNAGQRLQLQAQQVSLAGEVGAPTLDINGNELTVAGKVKGKLGAVAGGCVDQPGRGCRQGRPELAG
>NZ_CP010947.1|WP_158319748.1|1443854_1445294_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MTAIRFEGAGQLDADARTTLTHPFLHTCMGLPHINALIRDVSQWYLAQGFITSRAFLPEQDLASGTLTIAVLEGRVERIVVDGQPDRITHTLFPGLVGEVLNLRDLEQGVDQLSRLRTLSYQLDIQPGTAAGQSIVNLKGSRELPLQGSLEFDNSGQQSTGEEQGRMSLSADNLWSLAEQWSLGGSRSTDGRAAHDATSWQAGLSLPYGYWLFDAGYQYSDYRNDLLSRGYVYDSRGNTRTSTGTLSRTLYRDGQSKVSAVLGITHRQSRNFIMEQLLESSSYRLSSLRSGLNLATRVDHHFFTLNPTLTLSTDWFGADSDRGRPVAAPRAQFEKWGLFGSYSTAWQQLGWLSTLYGQWSPDTLYSVERVSLGGDASVRGFKEQSLSGDVGGYLRNELSWQAQTPAWLGQWRGWLALDMGRVDLGNQGDRWRGMVGTALGWEQRYRHVAGNLSVGFPISAPAWLNADPYVVNYRLSINF
>NZ_CP010947.1|WP_044799470.1|1441985_1443356_+|sodium:alanine-symporter-family-protein
MSSIQSALAAIDSFIWGPPLLILLVGTGIYLTLRLGLLQVVRLPLALRLVFGRDQGQGKQGDVSSFGALCTALSATIGTGNIVGVATAIKLGGPGALFWMWMAALFGMATKYAECLLAVKYRQQDANGQMAGGPMYYLEKGLGSRPLAKLFALFGIGVAFFGIGTFPQVNAISDAMSLSFSVPREVTAVVLTLIVALVTLGGIQSISSVSSKVVPFMAIFYIVACLGVLVNNAAALPEAIALVIGSAFTGHAATGGFVGAGIMLAIQSGVARGVFSNESGLGSAPIAAAAAKTDSCVEQGLVSMTGTFIDTIIICTMTGLTLVVTGVWSGDVSGAAMTSLAFAQGLDAHVGQYLVSIGLLFFAFTTILGWNYYGERCTEYLFGVKAIKPYRLIYLVLVASGAFLHLDLIWLLADIVNGLMAVPNLIGLIGLRHVVIAETRAYFSRDRDTESEPQTA
>NZ_CP010947.1|WP_011705184.1|1439975_1441127_-|type-III-PLP-dependent-enzyme
MNETLVAQDYRQLVEQFGSPLLLLDKAAVRKQYRALAAALPDVRLHYALKPLPHEAVVSVLKEEGACFDLATNGEVDLVRSQGVRPGRCIHTHPIKRDSDIRYALEYGCTVFVYDNPLELEKFIPYKDEVKLLLRVSFPNPETKVDLSKKFGCTPEQALPLLQLAHAKGIKVMGLSFHVGSQVPHARRHVQAIDACREIMEQAWELGLKPWVLDIGGGFPVDYEGGEFDIDGFCAPIREALAKLPATVQKIAEPGRFISAPAMTSVSSVMGKAHRGDKIWYYLDDGLYGSYNGQLYDHVTYPVSTPLARGELHNSVLSGPTCDSVDVIRDGIMLPDLAIGELVVGRVMGAYTWASASTFNFFPKASILILDSSQKGQKLVAVA
>NZ_CP010947.1|WP_044799469.1|1438941_1439910_+|calcium/sodium-antiporter
MTLAFVALIAGLALLVWSADKFVDGAAATARYAGMPPLLIGMVIIGFGTSAPEMVVSALAASQGNPGLALGNAYGSNITNIALILGLTALISPIAVASQVVRKEIPILLGITLLSGALLLDGHLDRTDAVILGVVFVGLMGWSIRAGMRGKGDALDAETEESIDSEGMSLKAAIGWLIVGLVLLIAASRLLVWGAVTIAQALGISDLVIGLTIVAVGTSLPELASSLIAIRKNEHDLALGNVLGSNLFNTLAVVGIAAGIHPLDVAPEVLSRDWSVMMGLTLLLLVMCLGRKGLGRINRLEGGLLLACFVAYTGWLLASQFI
>NZ_CP010947.1|WP_044799468.1|1438343_1438817_+|redoxin-family-protein
MIAIGQTLPAGEFTFITAEGKQQRDSQSLFGGKRVVLFAVPGAFTPTCSNAHLPGYVVLADQLMAKGVDAICCLSVNDAFVMKAWQDAQNAEAITMLADGDGSWTRALGLAKETGAFGGVRAQRFALIASDGVVEQLFVEAPGKFEVSDAQSLLAVL
>NZ_CP010947.1|WP_029301530.1|1437290_1438217_-|phenylacetate--CoA-ligase
MQHYYDGLEIRPSALREQQQLDQLNHLLTHVGQYCAGYSSAYRQRRLQDLGELTSLPLLNASELFAAQQAHPPFAGLTGRPASQALRVFACPGQLAIPEYAGADWWGAARALFAAGFKAGEVLLNGHDYHISPTAFIFDNGARQLGAPVVPCGPHDTGRQLEALQRYEPTGFVGPLAVLLDLLEAAERADVPSDSLRCALLCESSHPDTRPLQAVHGIRALNCLLLQDAGVIAYESQPGQGFIVNESCLIEIIDLASGEPVIGDGVGQLVVTRLDLEYPLLRLVTEWQGHWLAGASPCGRTNRRLRLI
>NZ_CP010947.1|WP_016349932.1|1436724_1437228_+|NUDIX-hydrolase-YfcD
MNKKGLRVEWVDVVDGNNQVVGVAERAKVRRENLCHRASYILVLDEADRILVQRRTLSKDFCPGMLDACAGGVVTTGELMEPSARRELAEELGIRDVPLQAFGDFYAEGEGYRVWGGLFSCRYQGPLQLQAEEVSEVCWMSQAEIAARAAEFTPDSLLAIATWQARR
>NZ_CP010947.1|WP_016349931.1|1436320_1436536_-|DUF1107-domain-containing-protein
MKVFKNLSPRQIARYIKSFHHGSFMVEAHGRFEFSGGEINLESLTCRQTLSLARQINLEVRGLRHTTLLLG
>NZ_CP010947.1|WP_044799467.1|1435463_1436210_+|amino-acid-ABC-transporter-ATP-binding-protein
MDSTKAVVELKEVNKWYGEFHVLRNINLQVGKGEKIVICGPSGSGKSTMIRCINRLEEHQSGDILVKGTALTSDLKNIETVRREVGMVFQHFNLFPHLSVLENCCLAPIWVKQLPRKEAEEIAMNFLRRVRIPEQALKYPGQLSGGQQQRVAIARSLCMNPQVMLFDEPTSALDPEMVREVLDVMVELAHEGMTMLCVTHEMGFAKQVADRVIFMDRGQIIEENVPDQFFDHPQSERTKLFLSQILQH
>NZ_CP010947.1|WP_144406117.1|1457109_1457457_+|hypothetical-protein
MNKNIFEIADGLITINDKAVNLPYPVVEAITIGEVVVVRIEPAVGELCNANIYGFTINGCFKWKIEESPHGTEPDKPFTSIYISPNGKLIAGNWNGIDYAVDVKSGAISAVAFNK
>NZ_CP010947.1|WP_052508931.1|1457615_1459301_+|DUF637-domain-containing-protein
MEAVQEAYEQWNYSQQSLSPIASAMIAIALAAATGGAGALAMGAAEGTATAAAMANAAFSTLVSQATISTINNGGNLGAVLKELGSSASIKQLATSVATAGALQGLDQAMGVASAAPAASNAASQPAASNLFSWDTFNRVTSHSVVTAGINTTINGSNFADSFKASLLSNIQGEVGKATANWIGDQGIKFDAANSPLAEAGKIAAHGVTSGAIAEISGGKFAAGAAGGAMSELASSWSSQVFSDTEHQVALNKVLGGLAAVAVTGDQNQFDTGAARAETIYRYNYLSHKDKSEQTSLRRAAEKGELTAEQKTRLAELNLKDVLSNESLLKACMHGSASECQTARQDALAKADTYPNLGYQYPKESLAGYQQIDRLLAGTTEEAIQTQRMYDGLVASYERIGMSAENAKTLVGYQLGAIYVFGGVAGAKSMASVEKGIAQNKLPNAKESSGAENVVNQGALNSQLLAEEVSRGHAYQKHVMERKEFVDLGVTTQRQFQTFVESIVSNPSIDRRQSVDGTTYYLDHSTKTIVIRGQRGEATAFRPDQGGVGWDNYIKSQVPKK
>NZ_CP010947.1|WP_144406120.1|1459297_1459504_+|hypothetical-protein
MSDKEENVELISLTITQRELRYFIASGLALVQNIPESSLPTYCGFNKDEIIAMSIKLRDFADELGIDM
>NZ_CP010947.1|WP_044799473.1|1460517_1461216_-|protein-ligase
MPYTLLPSLPSSHTPDQILAEEQRWLRECAHDRQPRAHLWQAPQCLIVTRKDTRLPRYQAACEQLAAEGWPVHVRDSGGTAVPHGAGIFNLSLMLPRTTTDLAHYYRLLGAPLLALLGEYGLTGSYDFVPGSFCDGQYNLVIGGRKVTGTAQRWLAPGQDHSGAVLAQAMLLVAGNVDEGTRMASRFYELAGGELRFLPATSTTIAQAIAWQGSEGELVERVREQLKQGLEE
>NZ_CP010947.1|WP_044799474.1|1461315_1462713_-|purine-permease
MEQAAAVRATREAHPPRRAHSELVYGIEDVPPLPQTLFAALQHMLAMFVAIITPPLIIANALGLPAADTRYIVSMSLVMSGIASFIQTRRFGPLGSGLLSVQGTSFNFLGPIIASGLALKQAAMPTEDLLGTLFGTMLAAALTIVVMSRFLHLVKRIITPLVTGIVVLLIGLTLIKVGLISMGGGYGALADGSFASHTNLFLSLLVLGLIVLLQRSRNPWLRLSAIMIAMLVGYAVALLLGKVNAPTFDGPLLMVPIPLHYGLGFDWQLFVPLAIIFVVTALEAIGDMTATSDISGEPLEGPVYMERIKGGVLADGANSMLAAVFSTFPMSTFAQNNGVIQLTGVASRHVGLFIATMLALLGLFPAVASLVQQIPEPVLGGATIVMFGTIAAAGVRIISREELDRRALMMLAVSLAMGLGVAQVPEVLQHLPDLAKSVLSYGVATGGLTAIIMNLLLPKRTAAQV
>NZ_CP010947.1|WP_011705188.1|1462958_1464098_+|GGDEF-domain-containing-protein
MLKLSEFWSARAHSEDFTLTRMGFMTVRLRLLTCLLMVGLPAWAVVDWLTLPSAQFDELFQARIFCLLALSPLIPFSYLIHFRRERMKLALGYLMAVMMLFSLICLHSFGADQELQAGYMAFPYLLISLFAIFPIPLSLGLQLAGGILVTMLAGNWLLVGQPLWSVQTLNQIWLLGLFALASSWVQCGQLNMLLQLYRESTTDELTGMMNRRLLMKQLEKARMSMIRKQAPFAVLLLDLDRFKRINDTFGHLAGDAVLKEVAATLAEQLEPGMVLGRYGGEEFAILLPNCAELAQAKRVAERLRVAVEARLVKSPTSDELLEVTVSIGLTLALRGEGVEDLLNRADECLYMAKMAGRNCVVGELGGKPAQPAAIQTDAA
>NZ_CP010947.1|WP_005298586.1|1464122_1464371_-|YciN-family-protein
MQPQKELITETALLEMANKIIKEHEDFIHGMRADSVEQKGEILVFKGEFFLAEDGTPTGKTMAVFNMFKLLAQQLSGKYQLG
>NZ_CP010947.1|WP_044799475.1|1464521_1465901_-|MATE-family-efflux-transporter
MNYWQAILKQTTDREFMTRLWRLALPVSLQSMMFSLLGLIDIMMVSQLGTTAVAAVGLGNRVFFFNLLVIAGLSGGVSVLAAQYYGRGEMAGVRRSLALALVGALLVSLPFALIYVISPGSVLGFASQEPALHALADQFLMITGATILCTAVVVPLESALRSVGNAAAPTRIGIIAIIANVILNYALIFGHFGFEAMGVAGSAWGTTLSRLLQTTLLLLYVRRYEARLIPRKDDWLAAFKRKEVVRFTLIALPLLFHDGLWAFGMLLYGFLYAHLGTDSLAIMTTLGTLESILISLFFGLAVACSTLLGHRLGAEEYEVAWQHSQLFLLLAPIGALLVGIAVWLLQTHLLQWVGNLPGELMTEAGQVLAIMCLGMLLKVFNMVGIIGVLRSGGDVNYSIFIDIVGMWCIGLPLAWGAVNLLGWPLSWVVAVVLLEELSKVLLVQRRIRQRRWLRNLVLG
>NZ_CP010947.1|WP_024944726.1|1466021_1466879_+|helix-turn-helix-transcriptional-regulator
MPFVSECLEIAPACEERMLGREGLPLLGEAGIFLTGLSSIRDHYLIRRNRPEFHILMVSHDEGGALLTDGGEQPIPAGSLIFLPAAVPGGLKLVGAQWRTSWILLDDVPRWQHLHRLGHRIWQGEEGEQLYHLLSLMQGEGTRSPLQPQLLSLLLALLERTLQGEVRGTPELRLQALFRRVEARLDEPWSVALLADQMACSVPHLHRLCQQAFGMGPMAKVTELRMNKARQLLLYTNWPLGELAGRVGYSDGANFANRFRRLTGLTPGAFRRLGRKPFATDVQTL
>NZ_CP010947.1|WP_044799476.1|1466947_1468642_+|NAD-dependent-malic-enzyme
MFEDNNQKRPLYIPYAGPALLETPLLNKGSAFTSEERSNFNLEGLLPQNIETIEEQAERAYRQFMAFGNDMDKHIYLRNIQDTNETLFYRLLTNHLTEMLPVIYTPTVGKACEEFSNIYRRARGLFISYPDKDRIDDMLQNATKQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYCLPVVLDVGTNNQQLLNDPFYMGWRNSRISGEEYAEFVDAFIQAVKRRWPDILLQFEDFAQNNAMPLLNRYKNELCCFNDDIQGTAAVTLGSLIAACKASGAKLSEKRVAFLGAGSAGCGIAEQIVAQMKAEGLTDAQARSRVFMVDRFGLITDKIPNQLDFQRRLSQPVERIADWPVGDNISLLEVMEHGRPDILIGVSGQPGLFTEEVVKTMHKHCARPIIFPLSNPTSRVEATPADLIRWTDGQALVATGSPFAPVEYKGKRYVIAQCNNSFIFPGIGLGVIAAGATRVTDAMLMSASRALAECSPLVKGEEGSLLPDLADIHQVSRYIAKMVAKTAMLQGKAVQTPDEVIDQSIEANFWRPEYRRYRRTSF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP010947_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_6

3120850-3120943

Orphan

Consensus_repeat	Method
GCCATCCGGCGTTTCGCGCCATTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_6

>merge|NZ_CP010947|6|3120850-3120943|CRISPRCasFinder
GCCATCCGGCGTTTCGCGCCATTCTGGCGTTGATCAAATAGCCCTCCTGCCGCCCGGCCTCTCCGTCCGGCCATCCGACGTTTCGCGCCATTCT

>NZ_CP010947|6|6|3120850-3120943|CRISPRCasFinder
GCCATCCGGCGTTTCGCGCCATTCT	GGCGTTGATCAAATAGCCCTCCTGCCGCCCGGCCTCTCCGTCCG
GCCATCCGACGTTTCGCGCCATTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_010633582.1\|3132144_3133521_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182324
NZ_CP010947.1\|WP_044800294.1\|3124147_3126529_+\|glycoside-hydrolase-family-3-protein	unknown	unknown	gnl\|CDD\|185053
NZ_CP010947.1\|WP_044800286.1\|3111273_3113472_-\|pilus-assembly-protein-FimV	unknown	unknown	gnl\|CDD\|274615
NZ_CP010947.1\|WP_029302701.1\|3114906_3116037_-\|4-phosphoerythronate-dehydrogenase	unknown	unknown	gnl\|CDD\|240635
NZ_CP010947.1\|WP_044800287.1\|3113747_3114764_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_CP010947.1\|WP_011706493.1\|3109301_3110165_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_CP010947.1\|WP_010633583.1\|3131494_3131782_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044800298.1\|3134549_3135107_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044800293.1\|3123267_3123726_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375918
NZ_CP010947.1\|WP_044800297.1\|3130589_3131402_+\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|235419
NZ_CP010947.1\|WP_029300144.1\|3110284_3111094_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP010947.1\|WP_044800290.1\|3119960_3120335_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044800289.1\|3118898_3119489_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376158
NZ_CP010947.1\|WP_029302700.1\|3116383_3117106_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|182658
NZ_CP010947.1\|WP_044800288.1\|3118460_3118823_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NZ_CP010947.1\|WP_044800292.1\|3121375_3123250_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173789
NZ_CP010947.1\|WP_029302699.1\|3117185_3118016_-\|membrane-protein	unknown	unknown	gnl\|CDD\|270317
NZ_CP010947.1\|WP_044800296.1\|3127902_3130281_-\|phosphoenolpyruvate-synthase	unknown	unknown	gnl\|CDD\|235809
NZ_CP010947.1\|WP_026080064.1\|3133788_3134493_-\|SIMPL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236840
NZ_CP010947.1\|WP_044800295.1\|3126624_3127602_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_010633582.1\|3132144_3133521_+\|amino-acid-permease	gnl\|CDD\|182324	PRK10238, PRK10238, aromatic amino acid transporter AroP.	0
NZ_CP010947.1\|WP_044800288.1\|3118460_3118823_+\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.77308e-34
NZ_CP010947.1\|WP_044800294.1\|3124147_3126529_+\|glycoside-hydrolase-family-3-protein	gnl\|CDD\|185053	PRK15098, PRK15098, beta-glucosidase BglX.	1.84845e-65
NZ_CP010947.1\|WP_044800286.1\|3111273_3113472_-\|pilus-assembly-protein-FimV	gnl\|CDD\|274615	TIGR03505, FimV_core, FimV N-terminal domain. This region is found at, or about 200 amino acids from, the N-terminus of FimV from Pseudomonas aeruginosa, TspA of Neisseria meningitidis, and related proteins. Disruption of FimV blocks twitching motility from type IV pili; Semmler, et al. suggest a role for this family in peptidoglycan layer remodelling required by type IV fimbrial systems. Most but not all members of this protein family have a C-terminal region recognized by TIGR03504. In between is a highly variable, often repeat-filled region rich in the negatively charged amino acids Asp and Glu.	2.96486e-25
NZ_CP010947.1\|WP_029302701.1\|3114906_3116037_-\|4-phosphoerythronate-dehydrogenase	gnl\|CDD\|240635	cd12158, ErythrP_dh, D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains. D-Erythronate-4-phosphate Dehydrogenase (E. coli gene PdxB), a D-specific 2-hydroxyacid dehydrogenase family member, catalyzes the NAD-dependent oxidation of erythronate-4-phosphate, which is followed by transamination to form 4-hydroxy-L-threonine-4-phosphate within the de novo biosynthesis pathway of vitamin B6. D-Erythronate-4-phosphate dehydrogenase has the common architecture shared with D-isomer specific 2-hydroxyacid dehydrogenases but contains an additional C-terminal dimerization domain in addition to an NAD-binding domain and the "lid" domain. The lid domain corresponds to the catalytic domain of phosphoglycerate dehydrogenase and other proteins of the D-isomer specific 2-hydroxyacid dehydrogenase family, which include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence.	0
NZ_CP010947.1\|WP_044800287.1\|3113747_3114764_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NZ_CP010947.1\|WP_011706493.1\|3109301_3110165_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_CP010947.1\|WP_029300144.1\|3110284_3111094_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	2.7468e-151
NZ_CP010947.1\|WP_044800297.1\|3130589_3131402_+\|kinase/pyrophosphorylase	gnl\|CDD\|235419	PRK05339, PRK05339, pyruvate, phosphate dikinase/phosphoenolpyruvate synthase regulator.	1.03962e-125
NZ_CP010947.1\|WP_044800289.1\|3118898_3119489_+\|hypothetical-protein	gnl\|CDD\|376158	pfam18735, HEPN_RiboL-PSP, RiboL-PSP-HEPN. RiboL-PSP-HEPN. Fused to endoRNase L-PSP ; in operon with ParB.	5.35337e-18
NZ_CP010947.1\|WP_029302700.1\|3116383_3117106_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|182658	PRK10699, PRK10699, phosphatidylglycerophosphatase B; Provisional.	4.07239e-35
NZ_CP010947.1\|WP_044800293.1\|3123267_3123726_+\|hypothetical-protein	gnl\|CDD\|375918	pfam18492, ORF_2_N, Open reading frame 2 N-terminal domain. This is the N-terminal domain found in ORF 2 (open reading frame 2), a protein encoded just downstream of asp (A. sobria serine protease). The ORF 2 N-terminal domain is essential for proper ASP folding. This domain is intrinsically disordered but forms some degree of secondary structure upon binding ASP.	1.95029e-31
NZ_CP010947.1\|WP_044800292.1\|3121375_3123250_+\|S8-family-serine-peptidase	gnl\|CDD\|173789	cd04059, Peptidases_S8_Protein_convertases_Kexins_Furin-like, Peptidase S8 family domain in Protein convertases. Protein convertases, whose members include furins and kexins, are members of the peptidase S8 or Subtilase clan of proteases. They have an Asp/His/Ser catalytic triad that is not homologous to trypsin. Kexins are involved in the activation of peptide hormones, growth factors, and viral proteins. Furin cleaves cell surface vasoactive peptides and proteins involved in cardiovascular tissue remodeling in the TGN, at cell surface, or in endosomes but rarely in the ER. Furin also plays a key role in blood pressure regulation though the activation of transforming growth factor (TGF)-beta. High specificity is seen for cleavage after dibasic (Lys-Arg or Arg-Arg) or multiple basic residues in protein convertases. There is also strong sequence conservation.	7.07736e-93
NZ_CP010947.1\|WP_029302699.1\|3117185_3118016_-\|membrane-protein	gnl\|CDD\|270317	cd13599, PBP2_lipoprotein_Gna1946, The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 periplasmic binding protein fold. Gna1946 shares significant structural and sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	6.04789e-133
NZ_CP010947.1\|WP_044800296.1\|3127902_3130281_-\|phosphoenolpyruvate-synthase	gnl\|CDD\|235809	PRK06464, PRK06464, phosphoenolpyruvate synthase; Validated.	0
NZ_CP010947.1\|WP_026080064.1\|3133788_3134493_-\|SIMPL-domain-containing-protein	gnl\|CDD\|236840	PRK11087, PRK11087, oxidative stress defense protein; Provisional.	4.51267e-82
NZ_CP010947.1\|WP_044800295.1\|3126624_3127602_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.03019e-18

>NZ_CP010947.1|WP_044800290.1|3119960_3120335_+|hypothetical-protein
MTPKQHLLAKAIFVVATMLSLAMIAFVAWAVVTVSPLHPADMAPSQSLSLGLATAIALFVLAFNYVAYRGFTEQVTAFKVVFWCFVALQLFAFPIGTVIALTLIYLWNQSRASLARPLGATVSL
>NZ_CP010947.1|WP_044800289.1|3118898_3119489_+|hypothetical-protein
MSKAIQGFEYSIKDAEELLAHFDGINANPPPPSSEVLKRAGLVMALTAWETYVEDRLVEEMHKKLAIVQGSYLGDFILKKLHADLKSFHNPTSDKTKKIFMDYLGFDVTEGWRWSNYEPDKARSTLNQWIKKRGEAAHRSKPISTGVLAPHLIKRDELEKVIRFIRDLVKSTDCYINEKIDLHHAAVFERQNQLST
>NZ_CP010947.1|WP_044800288.1|3118460_3118823_+|VOC-family-protein
MIDHVEIKTMHFADCKHFYQTVLRPLHMELKWADDAAAGFGLIGHDKVSFLIEKFDRNTPCHLAFSATTSAQVDAFHLAGIQAGFRCNGQPGPRVHYSPDYYAAFLLDPDGNNVEAVVHI
>NZ_CP010947.1|WP_029302699.1|3117185_3118016_-|membrane-protein
MQRRSFFTLSALALLAGTLPLAALAADPAKQEIVIGTTVGDFADMVTDSIKPQLEAKGYQVKLVEFTDYVTPNIALADGSLDVNCFQHKPYLESFAKDRGLSLAPITQVPTGPMGLYAGKLGELKAVKEGSTVAIPNDPTNQARALLMLQDLGWLTLKEGINPLKASEFDVVKNPHNLKLVLLEAAQLPRSREDVDFSVINGNFAASSGIPFSSGLFLERSYNFINWVVVKSADADKPFAKDVAAAYNSAAFKAYAAKRFVGYKYPEGWQGASASN
>NZ_CP010947.1|WP_029302700.1|3116383_3117106_+|phosphatase-PAP2-family-protein
MPTHASSLPRRQVLCFSAALILPLLLLACLPWQPFMSQALHSDWLWWPYALTRMVDVPGIAVSILALLLLTRHKLTLSLPALLALGGALFAVLAGDWLIKSLIKHLTEEPRPYLLWLESQQLIPAIQQFYAGKVEVRSEQVHAASQLLALPEWLANHWQAEVNYAFPSGHSIAAMSLAQFFGLIWLARAPVGAWLLPLWAIGVGLSRMLIGMHWPLDVLASALLGSLTALFAARWWLRHY
>NZ_CP010947.1|WP_029302701.1|3114906_3116037_-|4-phosphoerythronate-dehydrogenase
MKIVVDENMPHARELFAEFGEVIPLPGRQMQAVDLQEADVLLVRSVTRVDAALLASCPRLSFVGTATIGTDHVDKGLLAERGTPFFSAPGCNKYSVGDYVLSALLVLAERHELNLSAMSLAVIGAGNTGECVAGKAEALGMRVLRCDPPRARAAEANEAAQFVDYQQALEADIVSFHVPITRQGPDATFHLLDAAQIAARPAGQILINASRGEVWDNRALLARQQSQAPLRLVMDVWEGEPEPLQALVPHTELATPHIAGYSLEGKARGTWMLYEALCRQLGRTPRQDLQSLLPTPEVREVTPGQPADQALIKQLVHLIYDVRRDDARFRNRLGVAGSFDEQRKHYPERRELSSLQLKGPFAGDALARLGFVCQPD
>NZ_CP010947.1|WP_044800287.1|3113747_3114764_-|aspartate-semialdehyde-dehydrogenase
MSQQFNVAVLGASGAVGEAMIEILEERVFPIATLYPLASSRSAGDTVRFAGKNVEILDVEEFDWSQVQIALFSAGAEVSAKWAPIAAEHGCIVIDNTSCFRYDEDIPLVIPEVNPDALADFRNRNIIANPNCSTIQMLVALKPLHDEVGVARINVATYQSVSGSGKEGVSELAGQTAHLLNGRPVEPSLYPQQIAFNLIPQIDSFTDNGYTREEMKMVWETQKILGDASIAVNPTCVRVPVFYGHAEAVHVELHQPLDAEQVKELLRNAPGVTLFDDENDYPTPVRDATGKDEVLVGRVRQDISHPCGINMWIVADNVRKGAATNSVQIAELLVRDYL
>NZ_CP010947.1|WP_044800286.1|3111273_3113472_-|pilus-assembly-protein-FimV
MGHSRITLATLLALGLLGTAQAEDSAREPFFVELKGPDEPAPPAVNSQPLAQPVAAPRATSQPSRATAQPIVRQVASNAGSYGPIRPTDTLWSLASKYRPSSSVSVYQTMVAIYEKNPRSFADGNINHILVGSRIQLPTTAEASVITDAEARAKFRSDNASWKGLSPKYLASKHTQPAKPVATKAAQTKAAEPAKPEVAKVAPAKAAPIPAPAPKVETPQPATEVKAVAKAPEPVASQAAATSAATASAPAPLPADVNQPVGKPSTEMALALEDANAQLGQVTEMNHRLKLRLQSLTEEVETLKAQLQDQTALQKEIAELKAKPVPPVAPAPEPKQNWLMDLLSSPLNLAMIILLPVLLVLALVTLWLRARARRELEEQEKSLSESTAMVMDQESSEFDELMTVGITDDEPVRPRPDLNTPDGYMAVEEPAAPADLVFSDDGEMDLASFDAEPTPPAKAAIRDPDLVPELDLAHDESITLDTEPDLDLASEFNPKPKAGNEIMSEEELQAALFAELDADLEADLALDGSDDGQPDGDPMVSDEDLASFDLSDFETAFAEPGADKAASATVDASADELLAELGLEPEPTKGKQEAAADLEWDPNELALADFEDAFAEVESHPGEVKPREQAQESGYVEIDKLLAEADATTTEQEPYQGFSLDVGLDGFPEVLPESTGFDVDADDGGVGAKLDLARAYLEIDDKDSARELLQEAAEQGTEHQRAEAEKLLKRLG
>NZ_CP010947.1|WP_029300144.1|3110284_3111094_-|tRNA-pseudouridine(38-40)-synthase-TruA
MRIALGIEYDGSRYFGWQRQREVISVQEELEKALSRIANHPVSIQCAGRTDAGVHATGQVIHFDTDANRAEGAWTLGLNSNLPPDIAVRWVKQVDEGFHARFSATARRYRYVIYNHNYRPAILGSGVSHYHETIDADLMHQAGQSLLGEHDFSTFRAVACQSNTPWRNVTHLCVSRSGPYIVLDIKANAFLHHMVRNITGSLLLVGQGLQPVEWIAEVLAARDRNLAGPTAKAGGLYLVDVDYPAELGLPRMPLGPLWLPDSAPGTTSF
>NZ_CP010947.1|WP_011706493.1|3109301_3110165_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MSWLEKILPKSKITTPRRHNIPEGVWTKCSACEQVLYRAELERNLEVCPKCDHHMRISARARLESFLDEQGRTEIGAELEPQDVLKFKDSKRYKDRLSAAQKETGEKDALVVMKGTLKGVPVVACSFEFSFIGGSMSSVVGARFVRAVEESIKEGRGLVCFSTSGGARMQEALFSLMQMAKTSAALDRLSKAGLPYISVLTDPTMGGVSASLAMLGDINVGEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLEKGAIDLIIDRREMRNRLASLLAKMLNTHVIEE
>NZ_CP010947.1|WP_044800292.1|3121375_3123250_+|S8-family-serine-peptidase
MRKTSLALAISALLSALPIASVQASESCTPLTGKEAGLDTGRSSAARCLPGINPLQEQQWHLLNSGQNAFSPRGGVAGNDLNLWWAHRTSVQGQGINVAVVDDGLAIAHPDLADNVRPGSKNVVTGSSDPTPTDPDSAHGTSVSGLIGAVDNRIGTLGVAPRVQLQGFNLLDERSKQLQKDWIYALGGSTATADNRVFNQSYGMSLVDPQSASGLDQVQLDRLFEQQTQQAQGAAYIKAAGNGFNRIAAGDYMFSRTGVLPKLPFENSNIDPSNSNFWNLVVSAINADGVRSSYSSVGSNVFLSAPGGEYGTDAPAMVTTDLPGCDMGYNRTDDPSTNRLHNNPQLDATCDYNGVMNGTSSATPNTSGAMALLMSAYPDLSVRDLRDLLARNATRIDAGQQPVQVSYTAANGQPRQVTGLEGWERNAAGLWYSPTYGFGLIDVNKTLTAAANHTPLPPLVQLPAQKVTVPRSEGSIADVGSSATRSSTQVAQALTVEAVQVTVSLDHQRLPDLLIELVSPSGTRSVLLNPNNSLVGQSLDRQQLGYVRTKGLRDMRMLSHKFYGEAAQGEWRLEVTDVSNSSRQLTLVDLNTNRRSTLTERNNSQPGQLLNWSLRVIGHDAARS
>NZ_CP010947.1|WP_044800293.1|3123267_3123726_+|hypothetical-protein
MKHSLLGLALAGLLASAGVHAADESVVIDGKQYRTIEVNGQTYLTPDNGSKQRVARSADGKAPRQTLRSGDVLLQGVASPQLTASGTLLVEADDSQASALASRHGLRFKQSSGGIALLEAKPGTDLNAVATALKQEGVKVQIELAGALKQPK
>NZ_CP010947.1|WP_044800294.1|3124147_3126529_+|glycoside-hydrolase-family-3-protein
MPITTKLKAVSLGVSLALAGLLVGCNQNDSDPLVKDDAYYRGQAEAMVAKLTLGEKLDLLSGPGYGSANGAINVKQDVPGVAGYINGVLRSADGIDIPALKLADGPAGVRINANRDGDSASYYATAWPIGSLLASSWDVKLVKAVGEAMGDEVRQYGVDILLAPGMNIQRNPLNGRNFEYYSEDPLLTGKIGAAMVNGVESNGVGTTIKHYFGNNSETNRNQINDIGEPRTFREIYLRGFQIAVDEAQPWAVMTSYNKVNGTYVNERRDAVTDLLRGEWKFDGLVMSDWFAGDVANNAYKQVLAGQDLIEPGNVKEQLQQSIEHGDLDEAKVNEAAIHILTQVMKSPSYSQLAISNSPDLTAHAKLARQAGAESMVLLRNNAAALPLAANSTLASFGINQINTYKGGTGSGDVNAASTTTIAQGLAARFPVNEALQSYYRDFYENNKVYHEGQFGAKGYYTCAEAPISGDLAALIANAATTQQAAVISIGRQAGEGADRSSGKGDYLLGDDERALIDAVSSAFHAQGKKVVVVLNVNGVIDTAQWSDKVDGILLAYMAGQETGHAVADVLSGAVNPSGKLAQSFPHSYASVPSAGTFPGEDTDGDGEPDDLYYNEGIYVGYRYYSTFEQAVSYPFGFGLSYTSFSYTSPAIASNTLEGGSAGNLVLTATITNTGAVAGKEAAQVYVTAPEVKLKKPLIELKAFAKTAQLAPGASEQLSFTIPASILASFDEASNQWIVEPGRYSAYISPSSDVSASTPVSFTVSKEIVVSNTTPGALALPAGVDPASVTTITR
>NZ_CP010947.1|WP_044800295.1|3126624_3127602_-|AraC-family-transcriptional-regulator
MLGACQQQGGDPDAILMAGGLTSFDIEREQGRLPAHSHYRMLQLMQPYLASFHETILSYDIGQLYQHYPPLISLCLNQPSPRAALEVLLAYRPIIGSCDELRVRRGAQASQYLYVNQGPASLGASQAIPNFIMLYRILRVYLADPRVSVGFTGRPPPRHQLLDQFFATRCRWEQGENTLTIDNAQLDCPSHCYNEPLGHLQLAQLAQICADIAERAPFAYLVGERIRHKIREGELESDESLLKEVCAAMNVSRWTLNRKLQGEGSSFSTLLREARVSEACRLLGEGDQPLQNISDRVGFSSQSAFNRFFKANTRMTPLAYRNARQ
>NZ_CP010947.1|WP_044800296.1|3127902_3130281_-|phosphoenolpyruvate-synthase
MQVQQYVLWYEQLGMQDVERVGGKNASLGEMISNLSGAGVSVPGGFATTAFAFNEFLESSGLNGKIHDLLDSLDVDDIAALNRAGQQIRDWVIEAPFQSALEQAIRVAYDKLSGGLDASFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMIAVKHVFASLFNDRAISYRVHQGYDHKGVALSAGIQRMVRSDLAASGVMFTLDTESGFNDVVFITGAQGLGEMVVQGAVNPDEFYVHKPTLKAGRPAVVRKTLGSKLIKMTYSGDASHGRQVQIVDTNEAERSRFCITDAEVMELAKQALIIEQHYGRPMDIEWAKDGQDGKLYIVQARPETVRSRQEANTLERFALKQAGKVLIEGRAIGHKIGAGPARVISSISQMDEVQPGDVLVTDMTDPDWEPIMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATKRIEPGQLITVSCAEGDTGFIYDGELDFDVAVTEVGNMPRLPIKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVHPKALLEFDSQSPELKATIGKMIAGYESPREFYIAKLTEGIATLAAAFWPERVIVRMSDFKSNEYANLVGGRDYEPHEENPMIGFRGASRYIADSFRPCFALECEAIKRVRDVMGLTNVEAMIPFVRTVGEAEQVIDILAENGLRRGERGLKVIMMCEIPSNALLADKFLEHVDGFSIGSNDMTQLTLGLDRDSGLIAHLFDERNEAVKALLAMAIAAARKAGKYVGICGQGPSDHPDFAAWLVEQGIDSVSLNPDTVVDTWLYLAEQHKTN
>NZ_CP010947.1|WP_044800297.1|3130589_3131402_+|kinase/pyrophosphorylase
MHTVFYVSDGTAITAEVFGHAVLSQFPLAFEQITIPFVETLEKARQVRMRIDEQFRQTGVHPILFHTIVDHQVREEVLKAQASSHDFLNTFVSPLEHELGVKAEPRLHRTHGMENRKLYDDRIEAVNFALANDDGITTKEYEEADIILIGVSRCGKTPTSLYLALQFGIRAANYPFIEQDMGVLDLPAALKANRHKLFGLTIAPQRLHEIRNQRRANSRYSSLEQCEQELASVERLFRQEAIRFLDTSSHSVEEISAKILEATGLRRQLY
>NZ_CP010947.1|WP_010633583.1|3131494_3131782_-|hypothetical-protein
MQRIIGSLLAVALWLTVWLSPLLLTMAAGCLLVWAVQGDDYLVMHLRTVLLIAGAIGLLPALWLTERVRRRHGVLNFYAMLMNNKELNRPGSQPR
>NZ_CP010947.1|WP_010633582.1|3132144_3133521_+|amino-acid-permease
MDLQQNGEELKRGLKNRHIQLIALGGAIGTGLFLGIAQTIKMAGPSVLLGYAIGGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGDFAGFASGWNYWVLYVLVSMAELTAVGIYVQYWWPEIPTWMSAAFFFVLINAINLSNVKAFGEMEFWFAIIKVVAIIGMIGFGGYLLASGNGGPDASVSNLWAQGGFFPNGISGLVMAMAVIMFSFGGLELVGITAAEADNPEKSIPKATNQVIYRILIFYIGALAVLMSLYPWGKVVEGGSPFVMIFHALDSNLVATVLNMVVLTAALSVYNSCVYCNSRMLFGLAKQGNGPRSLLKTNKSGVPVVAISVSAAATLLCVLINYLMPGKAFELLMALVVSALVINWAMISLAHLKFRKSKQAEGVVPKFKAFWYPFGNYLCLAFMAGILVIMYLTPGIQISVLLIPVWIIVLAIGYQFKQKRQARVAANLG
>NZ_CP010947.1|WP_026080064.1|3133788_3134493_-|SIMPL-domain-containing-protein
MWRPLLTLSALVISAPLFALEVPQAPHLVVSGYAEQKAEPDMLTLNVSVTALEKQGIKAKQQVDGKVAAFFGQLEGLGIKRSDVEAGNLVISPEYQYPQNKKPELVGYRAQRQLAVKLYQLDKLSELMDTALKAGLESVSQIEYGLKAPQTIKEQARLGAVEDAKNKAESLAKAFGMKLGKVYSVEYRNNSPMPIYSRALKAAAMAPAADMMENSYQQQQITITDNVEAVFLLE
>NZ_CP010947.1|WP_044800298.1|3134549_3135107_-|hypothetical-protein
MQSFNWVDIDGIRYSWDGQGSITCTGQFGYHATMAGDRIDALDLESDDGEVAGSLNVDFAAATISFTPAVDAAPPHMMVLVGHEQGQQEYTLQSLSDVCLQDLLGHSDNIDCAPLVTTTMTEPVAPLAGHVLSWDSFHFDDDVLLGSRSATSLAAAHQGLPGGEISINIDMTNQVLDQIPPLHDI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP010947_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_7

4115282-4115381

Orphan

Consensus_repeat	Method
CCAAAATGTCGAAACGAATGCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_7

>merge|NZ_CP010947|7|4115282-4115381|CRISPRCasFinder
CCAAAATGTCGAAACGAATGCGGCACCTTACCAACCCGCTTTCAACGCCATGGCCTGATAACGACTCATGTCACCGCCAACATGTCGAAACGAATGCGGC

>NZ_CP010947|7|7|4115282-4115381|CRISPRCasFinder
CCAAAATGTCGAAACGAATGCGGC	ACCTTACCAACCCGCTTTCAACGCCATGGCCTGATAACGACTCATGTCACCG
CCAACATGTCGAAACGAATGCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_044800764.1\|4111262_4112576_-\|sodium-dependent-transporter	unknown	unknown	gnl\|CDD\|271367
NZ_CP010947.1\|WP_044800767.1\|4115546_4116788_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340888
NZ_CP010947.1\|WP_044800760.1\|4104277_4106323_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044800759.1\|4103719_4104184_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044800763.1\|4110545_4111262_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270422
NZ_CP010947.1\|WP_044800761.1\|4106292_4107018_+\|DUF3142-domain-containing-protein	unknown	unknown	gnl\|CDD\|371478
NZ_CP010947.1\|WP_044800762.1\|4107128_4108754_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381139
NZ_CP010947.1\|WP_011707344.1\|4113838_4114402_+\|DUF2799-domain-containing-protein	unknown	unknown	gnl\|CDD\|378521
NZ_CP010947.1\|WP_044800768.1\|4116954_4117575_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225222
NZ_CP010947.1\|WP_005304871.1\|4117883_4118360_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP010947.1\|WP_044800766.1\|4114452_4115274_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|182523
NZ_CP010947.1\|WP_044800770.1\|4119730_4120177_+\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP010947.1\|WP_044800769.1\|4118899_4119127_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225562
NZ_CP010947.1\|WP_016351944.1\|4118436_4118754_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225653
NZ_CP010947.1\|WP_017411099.1\|4108777_4110091_-\|sodium-dependent-transporter	unknown	unknown	gnl\|CDD\|271367
NZ_CP010947.1\|WP_044800772.1\|4121371_4121815_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240034
NZ_CP010947.1\|WP_144406154.1\|4117550_4117766_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044800771.1\|4120259_4121264_+\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176190
NZ_CP010947.1\|WP_044800765.1\|4112790_4113630_-\|isopenicillin-N-synthase-family-oxygenase	unknown	unknown	gnl\|CDD\|226022
NZ_CP010947.1\|WP_016351946.1\|4119162_4119588_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_044800764.1\|4111262_4112576_-\|sodium-dependent-transporter	gnl\|CDD\|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	1.90486e-164
NZ_CP010947.1\|WP_044800767.1\|4115546_4116788_-\|MFS-transporter	gnl\|CDD\|340888	cd17330, MFS_SLC46_TetA_like, Eukaryotic Solute carrier 46 (SLC46) family, Bacterial Tetracycline resistance proteins, and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of the eukaryotic proteins MFSD9, MFSD10, MFSD14, and SLC46 family proteins, as well as bacterial multidrug resistance (MDR) transporters such as tetracycline resistance protein TetA and multidrug resistance protein MdtG. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. TetA proteins confer resistance to tetracycline while MdtG confers resistance to fosfomycin and deoxycholate. The Solute carrier 46 (SLC46) family is composed of three vertebrate members (SLC46A1, SLC46A2, and SLC46A3), the best-studied of which is SLC46A1, which functions both as an intestinal proton-coupled high-affinity folate transporter involved in the absorption of folates and as an intestinal heme transporter which mediates heme uptake. MFSD10 facilitates the uptake of organic anions such as some non-steroidal anti-inflammatory drugs (NSAIDs) and confers resistance to such NSAIDs. The SLC46/TetA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.15946e-40
NZ_CP010947.1\|WP_044800763.1\|4110545_4111262_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270422	cd13704, PBP2_HisK, The periplasmic sensor domain of histidine kinase receptors; the type 2 periplasmic binding fold protein. This subfamily includes the periplasmic sensor domain of the histidine kinase receptors (HisK) which are elements of the two-component signal transduction systems commonly found in bacteria and lower eukaryotes. Typically, the two-component system consists of a membrane-spanning histidine kinase sensor and a cytoplasmic response regulator. The two-component systems serve as a stimulus-response coupling mechanism to enable microorganisms to sense and respond to changes in environmental conditions. Extracellular stimuli such as small molecule ligands and ions are detected by the N-terminal periplasmic sensing domain of the sensor kinase receptor, which regulate the catalytic activity of the cytoplasmic kinase domain and promote ATP-dependent autophosphorylation of a conserved histidine residue. The phosphate is then transferred to a conserved aspartate in the response regulator through a phospho-transfer mechanism, and the activity of the response regulator is in turn regulated. The sensor domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space through their function as an initial high-affinity binding component. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.47218e-16
NZ_CP010947.1\|WP_044800761.1\|4106292_4107018_+\|DUF3142-domain-containing-protein	gnl\|CDD\|371478	pfam11340, DUF3142, Protein of unknown function (DUF3142). This bacterial family of proteins has no known function.	2.55484e-14
NZ_CP010947.1\|WP_044800762.1\|4107128_4108754_+\|hypothetical-protein	gnl\|CDD\|381139	cd17624, REC_OmpR_PmrA-like, phosphoacceptor receiver (REC) domain of PmrA-like OmpR family response regulators. This subfamily contains various OmpR family response regulators including PmrA, BasR, QseB, tctD, and RssB, which are components of two-component regulatory systems (TCSs). The PmrA/PmrB TCS controls transcription of genes that are involved in lipopolysaccharide modification in the outer membrane of bacteria, increasing bacterial resistance to host-derived antimicrobial peptides. The BasS/BasR TCS functions as an iron- and zinc-sensing transcription regulator. The QseB/QseC TCS activates the flagella regulon by activating transcription of FlhDC. The RssA/RssB TCS regulates swarming behavior in Serratia marcescens. OmpR family DNA-binding response regulators contain N-terminal receiver (REC) and C-terminal DNA-binding winged helix-turn-helix effector domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	0.000508103
NZ_CP010947.1\|WP_011707344.1\|4113838_4114402_+\|DUF2799-domain-containing-protein	gnl\|CDD\|378521	pfam10973, DUF2799, Protein of unknown function (DUF2799). Some members in this family of proteins are annotated as yfiL which has no known function.	5.77187e-28
NZ_CP010947.1\|WP_044800768.1\|4116954_4117575_+\|transcriptional-regulator	gnl\|CDD\|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	1.24484e-53
NZ_CP010947.1\|WP_005304871.1\|4117883_4118360_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	3.22775e-48
NZ_CP010947.1\|WP_044800766.1\|4114452_4115274_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	7.95035e-83
NZ_CP010947.1\|WP_044800770.1\|4119730_4120177_+\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	2.69075e-56
NZ_CP010947.1\|WP_044800769.1\|4118899_4119127_-\|hypothetical-protein	gnl\|CDD\|225562	COG3017, LolB, Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane].	0.00983786
NZ_CP010947.1\|WP_016351944.1\|4118436_4118754_-\|hypothetical-protein	gnl\|CDD\|225653	COG3111, COG3111, Periplasmic protein with OB-fold [Function unknown].	0.00680281
NZ_CP010947.1\|WP_017411099.1\|4108777_4110091_-\|sodium-dependent-transporter	gnl\|CDD\|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	1.22259e-166
NZ_CP010947.1\|WP_044800772.1\|4121371_4121815_+\|NUDIX-domain-containing-protein	gnl\|CDD\|240034	cd04678, Nudix_Hydrolase_19, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	7.03002e-52
NZ_CP010947.1\|WP_044800771.1\|4120259_4121264_+\|NADP-dependent-oxidoreductase	gnl\|CDD\|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	8.9022e-171
NZ_CP010947.1\|WP_044800765.1\|4112790_4113630_-\|isopenicillin-N-synthase-family-oxygenase	gnl\|CDD\|226022	COG3491, PcbC, Isopenicillin N synthase and related dioxygenases [General function prediction only].	6.66761e-38
NZ_CP010947.1\|WP_016351946.1\|4119162_4119588_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.50891e-20

>NZ_CP010947.1|WP_044800766.1|4114452_4115274_-|Cof-type-HAD-IIB-family-hydrolase
MSRFQAIALDMDGTLLTRDHKISSATRAALAQARAHGIKVLLVTGRHFMTARPFHHELALDTPIICSNGAYLYDPVQEKIQVGDPLAVAPLSRLLAEVQAHQMGALFHLDEGIGYLGCEEHVTRMRHWSATQPDHLKISLLPAEDLASWLSRPVWKLELFNQDPALLHHFMAEVVEQLPFTRDWAAPYAVELVQPGCSKGNRLAQWAASEGIAMENVVAFGDNNNDISMFEQVGLAVAMGNAASQIQALADRVTADHNEDGIALALQRWVLPA
>NZ_CP010947.1|WP_011707344.1|4113838_4114402_+|DUF2799-domain-containing-protein
MSPKILLLTLPFLLAGCSSLSEEECRTMSWYNLGYQDGEQGKTRAATRDYVSTCGEYGLKVDEAEWKRGYAKGLELYCIPELAYSKGKSGAEYQGVCPNDASFLTQYDRGRQEYLVEKQLSDLKSDMERTERDIETLERQIRNENDSKQRDYYRAQRERAIRHYEGLRRDYNRIRFPDRVIQFSFGN
>NZ_CP010947.1|WP_044800765.1|4112790_4113630_-|isopenicillin-N-synthase-family-oxygenase
MKVLTVDYRSPDAAQRFTESLRTTGFGVLTNHPIPKELVQSIYDNWYRFFMSEQKQDFLFNRETQDGYFPPSVSEVAKGHSQKDIKEYFHLYPWGQMPAELKEQAMEYYRLANNLAAELLGWVEQYTPSYIAAHYSCPLSSMIEESQKTLLRVLHYPPFDGTEEPGAIRAAAHEDINLLTILPAANEPGLQVKGSDDEWMDVPCDFGTLIINIGDMLQEASHGYYPSTTHRVINPTGGSAAKSRISLPLFLHPRPDVVLSERHTAHSYLMERLRELGVI
>NZ_CP010947.1|WP_044800764.1|4111262_4112576_-|sodium-dependent-transporter
MKQSQWSSRLGYILAAAGSAVGLGAIWKFPYVTAANGGGAFLLVFLLFSFTLGVAVLMGETLLGSLSRRGVVGAFGALMGKRWRWVGAMGLLSSLLIYSFYSVVGGWTLGYTGMALAGSLQHGDGAALTARFNDYVGDPLWPVLTHLLFAGLTWWFVQGGVQKGVERTLRWMMPALFIMILMLVAFGLTLPNAMAGVRHFLMPDFSKLGMSGVLDAMGLAFFSLSIGLGIHTTYGAYLPSSDGVGRSSLWVVLLASLIAVLAGLMIFPVLAATGIDPASGPGLTFMTMPAVFQQLPFGQGLAVVFFALLVVAALSSAISLLEHLQCFVSEGLGWSRRAACGLITALVMAGGIPVSLSFGPWAQVTLFGKNIFELLDFVTSNLMMPMFGLALTLLLGWKLGRQALPAGLALHWRTLVMGCWRWLAPLLIGGILVRGLM
>NZ_CP010947.1|WP_044800763.1|4110545_4111262_+|transporter-substrate-binding-domain-containing-protein
MKWLLPWLLLPTLAQATQPPLTLLSHELPPFTHTSDGKLGGLAVQLVQEAQQEMGVDYPIKIYPLKRALALTRVEPGFALFVILRTPQREPQFKWVGPLFLNRVVIYQTRGSQPLTDLAQLRQLARVGVLLGNADDELLTREGYTNLVRCQTIEDAIERLMLGKIDAFPMGEQIMPAILAKMKFSPRSVVNSGLLLQENWLYIVFSKSEDDAVIARWQTAIDKVRDRHPQAQQPIRQP
>NZ_CP010947.1|WP_017411099.1|4108777_4110091_-|sodium-dependent-transporter
MSQVQWSSRIGHVLAAAGSAIGLGAIWKFPYVTATNGGGAFLLMFLLFSFTLGVAVLVGETLLGSRSQRGVLGAFHKLVGPNWRWMGYMGILCGFFIYSFYSVVGGWTVGYAALAVSGQLNLSEGAALTALFNGYVSHPWWPVLTHLVFAGLTWWFVQGGLQKGVERALRWMMPALFVMMMLLVVTGLSMPGAMAGVRQFLLPDFSMLTGQGVLDALGLAFFSLSIGLGVHTTYGAYLPSSEGVLRSGVWVVTLASLISVLAGLMIFPVLASTGIDPTAGPGLTFMTMPAVFNHLPFGQGLAVVFFLLLLVAALSSSISMLEHLVRFTTEEWGWSRRGACRVLTLLIMASGIPVSLSFGPWSELTLFGKTIFDLLDYLTSNLMMPLFGLVLTLLLGWRLGESVLPAGLSPLLRGCLLWCWRLVAPLLIAGILVRGLL
>NZ_CP010947.1|WP_044800762.1|4107128_4108754_+|hypothetical-protein
MQILLIEDDAMLSTALSRGLNEQGITPAQLTHCKELATLPTLLRQQSFDVVICRQYHHQAREGVRLLQEAHYLGLLEPGCVLLLLDEDHDQLQFPPSDLYFPLLLPMPFTADQLTASLCELVQLTGLTRTLPAPMKLREWQVSCALCEDLLYQQQKYRELGPLLDRIKGYMLLQQQDHFHAAQHYAVCTTEHDAWWPRKGLIHALLGLNKLESARKDLARNRERLPAPLQLELALACLLHERQWEGAWDVLTLLLQKQAWQPEWRQAAILLALLLKDEGKALEQANALSLRFFGDHKFRVSIDNFILNASLAVLWHYPSAARISALQQEYRYLSQAVTLRAHEEALLKALMLSLDYRFDEALLLLAKHPPESARDHHLNQLLGFAVSQFCGLPHHAQRYLSQLSQYQARVAPAPLVQQLFKQVIGDFMKQLERRELRLTYLRQERQRASAAGQHQLAVQYALTLQEEFPALPGDAWQLLELLQLCWPAGMAAPRVALLVDRLERRLNHSASFMEHHAEEYHKTLLQIRSHLNPRLPTTPPN
>NZ_CP010947.1|WP_044800761.1|4106292_4107018_+|DUF3142-domain-containing-protein
MGQAAQILLVMLALLGAEANAAVEASHYSQFWLWAGVRPQPVLQQAERLYLHQGEIGPLDARQPVRFQGQGIAPSKLPVKELWLAYRVERLDWDEALLKNLTNQLAAWQRKGNEVRGVQIDFDARTHRLANYGDFLRQLRRQLPADCAISITGLLDWTRTGDVATLNALAGVVDELVVQTYRGRRTEPGYARYLQALTRLTLPFKVGLVQGGEWDPTWESRLADSAAYRGAVVFLINSPGA
>NZ_CP010947.1|WP_044800760.1|4104277_4106323_+|hypothetical-protein
MKLTPLWLALCSLPALACGPDGCETPLTLQLTAAQCHLNGLPFLSPDNDTRTNLALLLADEQAFSLPKAPLPLPFAIEDLLNPTQAEPAPAGPDPLLALAAGLGIEQSTTQAALERAAGWSEGRCISNNPVAAEAFLQALVDTPALGADERSQLAHQRLAMLGQCAQQAETTPEDKAAPLSAAGQGFADYLAASRLFYQGEFAQADTLFAALAGQDQPWLKETADYMRIRVALNQSQQSAFDDWGTLDRNQIDQTAVQRAEQFIADYRGRYPEGRYLDSATGLLRRLAWFKGDEAALAGLFQQASRQPGNPELLNEIDLKLLMQPGFTGSAAMPQLTLVQDLRRLRLHESWDEWQPLQSGELAQQTAQFASNPVWLAYLQQAERYYLAKDYAAVITAAPALGKGPLDNLAFSQQVLKGMALAASQALPEAEQQWRALLASQPTPLQDQLLQLALAMTLERAGRLEQVFTKESPIQSDHYRIPLLEYVAPAPLLRRMVQDEQASDTLRQRAGNTLRYKQLTHGDYRGFLQDLALAPLAAPFDWQGSQEYQCPALTAVVTTLADNPNSPKALNCLGEFFLSQGLDWDQLLQRPGADTLAGSRDLFAGQQRSRLDWYQQVIASPKAAKEEKAYALYRAINCYAPSGNNSCGSQEIPLSQRKGWFNTLKRQYGTSQWAKQLKYYW
>NZ_CP010947.1|WP_044800759.1|4103719_4104184_+|hypothetical-protein
MHPTRAPLLLFTLLLGGCATPGHQQLGAALSGLEGELQRLEEELAAMNGLHYQKAIDAPLSLRRRLSAPVPTAQGLLPSRSTLTDGPLLRYDYRLPAGMASLPLTEPCLRYEFELRHLGRLGQLALHWQGAAGSGEQLIQQRYCPFSAKGPGLQ
>NZ_CP010947.1|WP_044800767.1|4115546_4116788_-|MFS-transporter
MDGIKGQASLWVLVMTVTLAVAGFSLPSPVLAPLMLDPAQGMLTPAASDWSRKVWLGVIMGLYPLFQLVGAPWLGKLSDRHGRKPVLTLCLVGVLVGYALMALGIAWRSLPLLLLSRVVEGFFNGDIAIVQAMAADMSTAKTKARSFAWINIGMNLGWVVGPMIGGYAAVVSGDYSLAAWLAVAMTLVNLLLVLWLLPNRPAAARSEQPPPALSSRQLLLQPTLLPYFVLTLLSYGAVQLYFTYFNVWLVERLAWDPVQLAQAAVMVSVPMILGSWLGSRLARHWRGSSLGVVGHLVMAAGMLMFVLPGHWWGLALTFIPTGIGMSLGELATSVAVSNRSHAEQQGQAMGLYRGLAVGSEILAVVVGSLVLLAGTEWSFYLAALCSLLCAIGFYGLRRAAARRQRLDVQVEAG
>NZ_CP010947.1|WP_044800768.1|4116954_4117575_+|transcriptional-regulator
MNASTEKILFLLKSHGPQSAAELGEQLQMTSMGARQHLMTLEADGWVSFNDEARGRGRPVRLWHLTEQAWQRFPDSHSELTLQLIDNIQQLFGEVGMERLIAQREQQQLARYQAELTQPALADRLAALTAQRTREGYMADFRQEEDGSWLLWESHCPICAAARACRGFCRSELEMFRRLLAPAGVEREQYLLEGDHRCLYRIRPQP
>NZ_CP010947.1|WP_144406154.1|4117550_4117766_-|hypothetical-protein
MVTSSGGKTETQPGLCGEGPYRVTNPISRLTLSGNDGLEREHPLPEGNKAGIPAPALLFLAFADQGCGLMR
>NZ_CP010947.1|WP_005304871.1|4117883_4118360_+|Lrp/AsnC-family-transcriptional-regulator
MLKLDRIDRHILELMQENGRISNLELAELVGLSPSPCSRRVKALEDAGLIDTHVTLLNARQLGLTLTAYIHISMDRHTPERFENFDRAISELPEVLECDLITGNDADYQLKVVVRDMEHYQHFLLDKLTHIPGVTGVRSSFVLRRIKHKTALPLNHLG
>NZ_CP010947.1|WP_016351944.1|4118436_4118754_-|hypothetical-protein
MQSSLVGLSILWGLASFGVQGDFIESRDSVAPSWQAESRVEMEGYLIESLGEDRWLFDNGSESLLVSLPEGQWVPTGERLRVSGEPQQEQAGWLLQVQDVSQVAV
>NZ_CP010947.1|WP_044800769.1|4118899_4119127_-|hypothetical-protein
MKLLLPLFALLLTACSAGSHAPSMAIDDADAWQAICKDGTRVRAVVEEGICADHRGVAMWTNKPRAARMAEEAAK
>NZ_CP010947.1|WP_016351946.1|4119162_4119588_-|MarR-family-transcriptional-regulator
MSELKKQVCFALYSASNAVMRAYRPLLDKLDLTYTQYLVMLSLWARDEVSLKEIGQETGLDAGTLTPIVKRLESKGWLTRTVSSEDERQKCIGLTEAGRQLQQEVRECCLADNLRNQVDLADAELAQLKQLCDRISAQLGR
>NZ_CP010947.1|WP_044800770.1|4119730_4120177_+|organic-hydroperoxide-resistance-protein
MKTLYRTQAIAQAGRNGEVHTLDNSLQLALALPTALGGNGKGNNPEQLLAAGYAACFSNALIHVAHKLGAPLSSAPVTAGVELLAQADGRFNFAITLDVALAATQPEQAAQAEQIVRLAHQTCPFSNAMRGNVVTRLLLNGAPLDETA
>NZ_CP010947.1|WP_044800771.1|4120259_4121264_+|NADP-dependent-oxidoreductase
MNQSSHQIQLLRRPVGLPSLADFTLTEVALPELQEGEVRVANQWLSVDPYMRGRMSDAKSYVPPFPLNGPLDGGAIGVVEASRHPDFAVGDRVSSMLGWRDRFVANGAQLTRLPDTRLPPQLFLGALGMPGMTAWTGLNRIAKLQAGETVLVSAASGAVGSMVVQLAKRAGARVIGSTGSTDKVAYLKSLGADEVINYRETPDLDAELARLAPEGIHVDFENVGGAMLDAALNHMVVHGRIVMCGLIEQYNGQSEASGPRNLSQVIRKRLTMQGLIVFDHWQHYGEFLAEVTPAFDSGTLQAEETVYQGLASMPQAFIGLFEGRNTGKMLVKLT
>NZ_CP010947.1|WP_044800772.1|4121371_4121815_+|NUDIX-domain-containing-protein
MSTPYPRVGVGVILTNRQGQVLLGKRKGSHAPYWSIAGGHLELGETFESAAIREVAEETGFQISNPSVIAVTNNLETWRESGLHYVSVTLLAEVEGEPQLLEPEKCEGWVWCDPRNLPEPHFDASRQSIACWLAGRCYLPTPHQPTP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP010947_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_8

4654782-4654926

Orphan

Consensus_repeat	Method
CCCCAGACACTTACTCAGCAAGCCAGATAATCGAGGCCATGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_8

>merge|NZ_CP010947|8|4654782-4654926|CRISPRCasFinder
CCCCAGACACTTACTCAGCAAGCCAGATAATCGAGGCCATGCGACCGGTCTGGCCATTGCGACGACATGGGCAGTAGCACTGCTCGCGGTATGGGAGGACGCCCCCAGACACTTACTCAGCCAGCCAGATAATCGAGGCCATGCG

>NZ_CP010947|8|8|4654782-4654926|CRISPRCasFinder
CCCCAGACACTTACTCAGCAAGCCAGATAATCGAGGCCATGCG	ACCGGTCTGGCCATTGCGACGACATGGGCAGTAGCACTGCTCGCGGTATGGGAGGACGC
CCCCAGACACTTACTCAGCCAGCCAGATAATCGAGGCCATGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_029302296.1\|4662420_4663173_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270422
NZ_CP010947.1\|WP_026080327.1\|4666798_4667962_-\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|185092
NZ_CP010947.1\|WP_044801018.1\|4648379_4649144_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366132
NZ_CP010947.1\|WP_044801019.1\|4649853_4650846_+\|aspartate--ammonia-ligase	unknown	unknown	gnl\|CDD\|235456
NZ_CP010947.1\|WP_044801023.1\|4655816_4656797_-\|23S-rRNA-pseudouridine(1911/1915/1917)-synthase-RluD	unknown	unknown	gnl\|CDD\|183020
NZ_CP010947.1\|WP_011707730.1\|4649238_4649700_-\|transcriptional-regulator-AsnC	unknown	unknown	gnl\|CDD\|183019
NZ_CP010947.1\|WP_011707742.1\|4663268_4664753_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|236520
NZ_CP010947.1\|WP_011707725.1\|4646013_4646529_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|376515
NZ_CP010947.1\|WP_044801021.1\|4651941_4654515_-\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NZ_CP010947.1\|WP_041216793.1\|4646531_4647236_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180586
NZ_CP010947.1\|WP_077392317.1\|4656905_4657670_+\|outer-membrane-protein-assembly-factor-BamD	unknown	unknown	gnl\|CDD\|274513
NZ_CP010947.1\|WP_044801020.1\|4651056_4651881_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293799
NZ_CP010947.1\|WP_044801025.1\|4659235_4660636_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP010947.1\|WP_011707745.1\|4668108_4669011_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377694
NZ_CP010947.1\|WP_017409791.1\|4645791_4645884_-\|YnhF-family-membrane-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044801026.1\|4660801_4662109_-\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP010947.1\|WP_011707743.1\|4664764_4666291_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|236507
NZ_CP010947.1\|WP_044801017.1\|4647356_4647761_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341392
NZ_CP010947.1\|WP_041216795.1\|4647757_4648294_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227700
NZ_CP010947.1\|WP_044801024.1\|4657810_4659139_-\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|181958

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_026080327.1\|4666798_4667962_-\|alcohol-dehydrogenase	gnl\|CDD\|185092	PRK15138, PRK15138, alcohol dehydrogenase.	0
NZ_CP010947.1\|WP_044801018.1\|4648379_4649144_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|366132	pfam00497, SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.	3.11537e-23
NZ_CP010947.1\|WP_044801019.1\|4649853_4650846_+\|aspartate--ammonia-ligase	gnl\|CDD\|235456	PRK05425, PRK05425, asparagine synthetase AsnA; Provisional.	0
NZ_CP010947.1\|WP_044801023.1\|4655816_4656797_-\|23S-rRNA-pseudouridine(1911/1915/1917)-synthase-RluD	gnl\|CDD\|183020	PRK11180, rluD, 23S rRNA pseudouridine(1911/1915/1917) synthase RluD.	0
NZ_CP010947.1\|WP_011707730.1\|4649238_4649700_-\|transcriptional-regulator-AsnC	gnl\|CDD\|183019	PRK11179, PRK11179, DNA-binding transcriptional regulator AsnC; Provisional.	1.36867e-111
NZ_CP010947.1\|WP_011707742.1\|4663268_4664753_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta	gnl\|CDD\|236520	PRK09444, pntB, Re/Si-specific NAD(P)(+) transhydrogenase subunit beta.	0
NZ_CP010947.1\|WP_011707725.1\|4646013_4646529_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|376515	pfam01288, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK).	4.90755e-22
NZ_CP010947.1\|WP_044801021.1\|4651941_4654515_-\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_CP010947.1\|WP_041216793.1\|4646531_4647236_-\|SDR-family-oxidoreductase	gnl\|CDD\|180586	PRK06483, PRK06483, dihydromonapterin reductase; Provisional.	5.22098e-72
NZ_CP010947.1\|WP_077392317.1\|4656905_4657670_+\|outer-membrane-protein-assembly-factor-BamD	gnl\|CDD\|274513	TIGR03302, OM_YfiO, outer membrane assembly lipoprotein YfiO. Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking].	5.41351e-100
NZ_CP010947.1\|WP_044801020.1\|4651056_4651881_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293799	cd07713, DHPS-like_MBL-fold, Methanocaldococcus jannaschii dihydropteroate synthase, Thermoanaerobacter tengcongensis Tflp, and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase (EC 2.5.1.15), a folate biosynthetic enzyme also known as dihydropteroate synthase and 7,8 dihydropteroate synthase. Thermoanaerobacter tengcongensis Tflp is a ferredoxin-like member. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.38393e-78
NZ_CP010947.1\|WP_044801025.1\|4659235_4660636_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP010947.1\|WP_011707745.1\|4668108_4669011_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|377694	pfam06719, AraC_N, AraC-type transcriptional regulator N-terminus. This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.	2.77284e-49
NZ_CP010947.1\|WP_029302296.1\|4662420_4663173_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270422	cd13704, PBP2_HisK, The periplasmic sensor domain of histidine kinase receptors; the type 2 periplasmic binding fold protein. This subfamily includes the periplasmic sensor domain of the histidine kinase receptors (HisK) which are elements of the two-component signal transduction systems commonly found in bacteria and lower eukaryotes. Typically, the two-component system consists of a membrane-spanning histidine kinase sensor and a cytoplasmic response regulator. The two-component systems serve as a stimulus-response coupling mechanism to enable microorganisms to sense and respond to changes in environmental conditions. Extracellular stimuli such as small molecule ligands and ions are detected by the N-terminal periplasmic sensing domain of the sensor kinase receptor, which regulate the catalytic activity of the cytoplasmic kinase domain and promote ATP-dependent autophosphorylation of a conserved histidine residue. The phosphate is then transferred to a conserved aspartate in the response regulator through a phospho-transfer mechanism, and the activity of the response regulator is in turn regulated. The sensor domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space through their function as an initial high-affinity binding component. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.14256e-21
NZ_CP010947.1\|WP_044801026.1\|4660801_4662109_-\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	7.6601e-137
NZ_CP010947.1\|WP_011707743.1\|4664764_4666291_-\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	gnl\|CDD\|236507	PRK09424, pntA, Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha.	0
NZ_CP010947.1\|WP_044801017.1\|4647356_4647761_+\|CBS-domain-containing-protein	gnl\|CDD\|341392	cd04629, CBS_pair_bac, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	9.369e-57
NZ_CP010947.1\|WP_041216795.1\|4647757_4648294_-\|hypothetical-protein	gnl\|CDD\|227700	COG5413, COG5413, Uncharacterized integral membrane protein [Function unknown].	4.24078e-28
NZ_CP010947.1\|WP_044801024.1\|4657810_4659139_-\|CoA-disulfide-reductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	0

>NZ_CP010947.1|WP_044801021.1|4651941_4654515_-|ATP-dependent-chaperone-ClpB
MRLDRLTSKFQIAISDAQSLALGRDHQFIEPVHLMTALVNQDGGSIRPLLTLTGMDINSLRSRLGEELDRLPRVSGVEGDVQLSNGLGRLLNVCDKLAQQRKDQFISSELFVLAALDEKGALGELLRAQGLTKEKLEAAIDKVRGGKKVEDANAEENRQALEKYTIDLTERAEIGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGAPGVGKTAIVEGLAQRIINGEVPEGLKNKRVLSLDMGALVAGAKYRGEFEERLKAVLNDLAKEEGNVILFIDELHTMVGAGKGEGAMDAGNMLKPALARGDLHCVGATTLDEYRQYIEKDAALERRFQKVLVEEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAAQLSHRYIADRQLPDKAIDLIDEAAASIRLQIDSKPESLDRLERRIIQLKLEQQALMKEDDDASRKRLELINQEISEKDREYNELDEVWKAEKAALAGTQHIKAALEQARQDLDVARRAGDLGRMSELQYGRIPELEKQLDLATQAEMQETSLLRNRVTDVEIADVLARWTGIPVARMLEGERDKLLRMEDQLHSRVIGQEEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALAEFLFDTQDAMVRIDMSEFMEKHSVARLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNSVVIMTSNLGSDLIQEHHSEKDYDEMKGMLMEVLTRSFRPEFINRIDETVVFHPLGEEHIKSIARIQLKSLMGRLEAQGYEVEVSEALLEKLVHAGFDPVYGARPLKRAIQHKVENPLAQALLSGRIVPGKKLVLGADSNGLTMTQ
>NZ_CP010947.1|WP_044801020.1|4651056_4651881_-|MBL-fold-metallo-hydrolase
MLKFSVLVDDDVHLPGCLPERGLALLLECDGLRVLFDSGRGRALCHNAAVMGIDLASLTHVVLSHGHYDHVGGVGSLPVYPRPIPLIACPDVFCERGYFLSLPFWRRNLYRLSGELARESLPARGLLPHCSAEPVWLSERLVFLGSILRRDKAAPSLLGYIVRGGRVEKDLISDDSALAYKSEQGLIVFIGCGHAGVENIIERAKEVCGDERIHAVIGGLHLKFSGPERAVALGAYLREEAVDQLFACHCTGRRKAGLPRQRQIGAGFEHRFSV
>NZ_CP010947.1|WP_044801019.1|4649853_4650846_+|aspartate--ammonia-ligase
MKQHYIRSQQQISFVKEMFSRQLAQQLGLMEVQAPILSRVGDGTQDNLSGHENAVQVKVKTLPEHSYEVVHSLAKWKRQTLGRFGFGPGEGIYTHMKALRPDEDRLTPIHSVYVDQWDWEKVMPSERRDLAYLQETVRGIWAAIKATERAVCAEHELTPFLPAEIQFLHSEELLTRYPDLDAKGRERAITKELGAVFLIGIGGALSHGERHDVRAPDYDDWSSHSELGLAGLNGDILVWNPVLQDSFEISSMGIRVDAEALRRQLAITGDEDRLQYDWHQDLLAARMPQTIGGGIGQSRLAMLLLQKEHIGQVQVGVWPAEMKAAVQGML
>NZ_CP010947.1|WP_011707730.1|4649238_4649700_-|transcriptional-regulator-AsnC
MPENYRIDNLDQAILTALMENARIPYAELAKQLLVSPGTIHVRVEKMKQAGIIEGTRVQVNPKKLGYDVCCFIGINLKSAKDYPSALAKLQALDEVVEAYYTTGHYSIFMKVMTRSIDELQTVLIHKIQTIDEIQSTETLISLQNPILRDVKP
>NZ_CP010947.1|WP_044801018.1|4648379_4649144_+|transporter-substrate-binding-domain-containing-protein
MRRFILLCLLFPLWLQAKELIIGGTLEPPLKYLDAQGVPHGLDVDVVSTIFGKLRIPIRIELTDSGARLTRNAETGVYDLVMTHSYKPERERYLLYPQQAHLRHSWHFFVRKADLLKIRYDTLADLKPWRIGITKDFSYTPELTAALADPAYHFQEIPINQLQLRKLIAGRIDVVPMPLVTAFAQIKEEGLEGKLDYLPKPLKASPYYTVWTKAKADATTPALMAAYDAELLRMKRDGRLKAIYDHYGIPYIEP
>NZ_CP010947.1|WP_041216795.1|4647757_4648294_-|hypothetical-protein
MANPEIESELDGIDRVSVCLYRLGLSLAALLLLCRGASLLLGQDFLAPASWLVALAVASGVCGLCLHVYDKRIRFVLQGLGWGALLLSASGAPDVLVLGAALATLAGLAFKEQFCFAIPGIRAVPLLLPLLWLLELAGIGWAAALVALVCGLLLCLLSLAKWRMPLHFDIGDKGRYQI
>NZ_CP010947.1|WP_044801017.1|4647356_4647761_+|CBS-domain-containing-protein
MLQIRDHMSRSTHSLTPQLGLAEALDRLHDSGLSGLPVLDPQQRLIGFLSEQDCIPSLLTGSYHCDTRTQVEDLMSRTPLSVSPDDSILDLARQMTEARPKVYPVLEGNRVVGIISRRQVMQALNAQMKACLPT
>NZ_CP010947.1|WP_041216793.1|4646531_4647236_-|SDR-family-oxidoreductase
MRALVTGCGRRLGFYLCEQLVAAGWQVTGSYRSERPELARLRSIGVELVQADFAREEEVGTLIEALAVHQDLALVIHNASAFEPQAADPAAQLAQFDQFYRVHMAAPFQLNRALASQLARNANAGIIHITDIYIHAPAPQFASYVATKAGAHSLAMSFARELAPAVRVNTIEPGPILFLDEHGEAWRQQVLAKTPLAREGGLAPIWQAVQLLMQNDYMTGASIRVDGGRGLAVI
>NZ_CP010947.1|WP_011707725.1|4646013_4646529_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MFYLCSIGSNLDPHQHVSQAVGELLVHFGRLQLSSVIQTKPVGMHSSHDFLNCLFVAESELAPHQLKAHFVAMELAHGRDRSDPRCKVLDRPLDIDILASSQSDDFSTARVDAYLDELLAELYGRGQVHDRKVTLPLHTRLMAGKVIEERQVGLAPIALQQEMATPAALLR
>NZ_CP010947.1|WP_017409791.1|4645791_4645884_-|YnhF-family-membrane-protein
MSVELKWALLTASGALAMILIICVASVGLA
>NZ_CP010947.1|WP_044801023.1|4655816_4656797_-|23S-rRNA-pseudouridine(1911/1915/1917)-synthase-RluD
MSQHIELTGEFQDHQFGQRLDQALAELFPDYSRTRIKEWILQDRVTLDGQVANTPREKVLAGQKVHVDVELADDTRWDAQNIELNIVYEDEHILVIDKPAGLVVHPGAGTPDGTILNALLHRYPTIAEVPRAGIVHRLDKDTTGLMVVAKTIPAQTHLVEALQARQITREYEAIAIGHMTAGGTVDAPIGRHPTQRTHMAVVPNGRESVTHYRVHEKFRGHTRLRLRLETGRTHQIRVHMAHIKHPLVGDPAYGGRLRLLRNATPELTEALRGFHRQALHATMLKLAHPITGEVMEWHSPTPQDMLDLMEVLRADTLANPDDLVWN
>NZ_CP010947.1|WP_077392317.1|4656905_4657670_+|outer-membrane-protein-assembly-factor-BamD
MLLMGKKSHLLMSLALVATLITGCSSTKPKVPDEPPETLYQKARLKLDAGNYLNAIELLEALDSRYPFGAYSNQVQLDLIYAYYKQDDTAQAIANIDRFIRLNPAHKNIDYVFYMRGLTNMAGDYNFFQDFLGINRDDKDPSYARQAFQDFKTLLQNYPNSVYAADARARMIGLKNRLARYDLSVAEYYVKRDALIAAANRAKLIVETYPDTAETEKALEIMINSYDSLKMPTLAQHAREVLAKNYPDNRLGRG
>NZ_CP010947.1|WP_044801024.1|4657810_4659139_-|CoA-disulfide-reductase
MRIVIIGGEAAGMSAAAKARRLAKEAEIVVYEASEVISFGACGLPYFVGDEFQEPGYMAEFTPEQFAAKGIEVKTGHRVLGLDATAQTLTVEHKGDTFTDRYDRLMIATGAREVMPPIPGLQQEGVFGLRRMADGLALKAAVQDQANGRALVIGSGFIGLEVVEALVHQGKEVRLIELAERVIPDAFDGEITQHIETELREQGVSLHLGERVEALLGVGRVTGVRTSHGEYEADIVVVCTGVKPNTEFLADTGIERLGNGAIKVDRQGRSSLANVWSAGDCASVWHSVKQQQVYVPLATIANKLGRMVGENLAGAEQEFPGTLGSAALKVLGLEAGRTGLSEQEAKAMGIDYRTVVIKDKCHTNYCPGQSDIHVKLVYEAGSKRLLGGQILGRKGAVHRIDALAVAITMGVTTEQLGMLDFAYAPPFSRTWDVLNVAGNVAK
>NZ_CP010947.1|WP_044801025.1|4659235_4660636_-|L-cystine-transporter
MTLSVIGNLAILVMLLLFLYRLQQTHVSFTRRVFSGLGLGILFGAALQLLYGAGSDVLVQTGDYLDIVGSGYVKLLQMIITPLIMVSIIGAILKLNGGTALGKISAMTIGVLIFTTMIAAGAGILMSNLFGLTAEGLTAGSAETARGAALQTTLGSVESMSFAKMVLEFIPANPFLDMTGARKTSTIAVVIFSIFIGLSATGIARKKPEIFASFGHFMQVAHVIVMRMVTLVLRLTPYGVLALMTKVVSGSNYADILNLLSFVMASYGAIAIMFVVHLLLVSLVGINPARYLKKIMPVLAFAFTSRTSAGSIPMNVQTQTKALGIPEGIANFAASFGSTIGQNGCAGIYPAMLAVMIAPTVGVNPMDPGFIMTLIAIITVSSFGVAGIGGGATFAALIVLSALDFPVALAGLLISIEPLIDMGRTALNVSGSITAGTVTSRLLGETDMAVFNSEHEVCLDGEESTI
>NZ_CP010947.1|WP_044801026.1|4660801_4662109_-|serine-dehydratase-subunit-alpha-family-protein
MRHIAMKAQWTDFITLLKREVVPALGCTEPMSVALAAANCRKLLGQVPTRVSVWVSGNLFKNGMGVGVPGTGMIGLPVAAAVGITGGNPDAGLEVLKTLTPDQVEAAKALLPAIKVDVKDVPDVLYAEVLAEVEGHSARVVICTDHTRIILMERDGEVLMAQDSAPGVQIQAAPSSKPTMTLREIVEFALQVPLAEIDFIREAATMNQALADEGLQGYGLRIGKILTEQVERKLLSDDLMTLAMRLSSAASDARMDGAMLPAMSNSGSGNQGIAATMPVVAAARFLQASDEQLTRALVMSHLVAIYIKTYQNKLSALCAASTAAMGAGAAITWLLGGQFEQISHCINNMIGDVSGIICDGAGSACSMKVSTSTSAAVKSSLMAINNLHVPQSEGIVSDDVDETIANLGRLSKQGMLDTDIEIINIMRAKQQGKAE
>NZ_CP010947.1|WP_029302296.1|4662420_4663173_-|transporter-substrate-binding-domain-containing-protein
MVWRKGWILLCLWWGWAAQASEPPTLTLLTELWPPYVMRLDDGSLGGADLELARTVLKRMGYQTTVKVLPWKRVLQEARLQRGDAIVDAFFEERRLEWLHYPDEPLSQSGEVLFFPLARPVDFQGLASLKGLRIGTQTDYAYGEEFLTSALFTRVAMTGESNMIKQLHLMMAGRLDGVVMNQMVGRYLLKGQGLQDQVGHSEKLVSESNRNFLAFTHRPGNERLAYQFSLALKAFKQTPEYQSLLTRYGL
>NZ_CP010947.1|WP_011707742.1|4663268_4664753_-|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta
MSQGLVTASYIVAAVLFILSLAGLSKQETAKHGNLFGIAGMAIALLATVFNPETSGVHWIILAMVIGGAIGVRLALKVEMTEMPELVAVLHSFVGMAAVLVGFNSFIDLHPSAPAEVVVSVGSNLDATLAAARAAFEQAASVAQVEHLSGAMLNIHLVEIFLGVFIGAVTFTGSVVAFGKLRGLISSKPLMLPHRHKLNLLAVVASLALMVYFVNAGGSTFALLVMTLIAFAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGSDGVASTADQEMGEYRETSAEDVADLLKNSSSVIITPGYGMAVAQAQYPVAEITQKLRDRGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINEDFSDTDTVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKENTQMLFGDAKASVEAILKAL
>NZ_CP010947.1|WP_011707743.1|4664764_4666291_-|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha
MQIGIPRESLAGETRVAATPATVEQLKKLGFEVAIEAGAGLLASFDDAAFEAAGASVVPSVWQADLIFKVNAPTDAEIAQIKDGATLVSFIWPAQNPELVKKLSARNINVMAMDMVPRISRAQSLDALSSMANIGGYRAVVEAAHQFGRFFTGQITAAGKVPPAKVLVIGAGVAGLAAIGTAGSLGAIVRAFDTRLEVAEQIESMGGEFLKLDFGGEDGSSSDGYAKVMSEEFIAAEMALFAQQAKEVDIIITTALIPGKPAPKLITKEMVDSMKPGSVIVDMAAQAGGNCEYTVPGELHVTGNGVKVIGYTDLPGRLPAQSSQLYGTNLVNLMKLMCKEKDGNVAINFEDVVQRNMTVIQAGEVTFPPPAISVSAAPQKPAAAKPAAKKEAAKPSNKKFVFGALGIAAFGWVAAVAPAAFLSHFTVFILACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGQGSTLVTALAFVAVLIASINIFGGFTVTQRMLKMFRKD
>NZ_CP010947.1|WP_026080327.1|4666798_4667962_-|alcohol-dehydrogenase
MNNFTLHTPTKILFGKGQVAQLREQLPRDARILITYGGGSVVRSGLLAQIRSELAGMTLFEFGGIEPNPTYETLMGAVELARAERVDFLLAVGGGSVLDGTKFIAAAAHYDPARDPWHILETVGNEVRSAIPLGAVLTLPATGSEMNMGAVVTRRSSGDKVHFFSPFVMPRFAVLDPVLTYTLPARQVANGVVDAFIHILEQYLTYPVNAKVQDRFAEGLLLTLLEEGPKALVEPENYEVRANIMWSATLALNGLIGAGVPQDWATHMLGHEITALHGLDHAQTLAVVLPALLQAKRQQKHAKLLQYAERVWDLRSGSEAERIDGAIAATRDFFERMGVKTRLRDYGVADAGIDTLLGKLAEHGMTAIGEHGDIDLVQSQHIYEAAW
>NZ_CP010947.1|WP_011707745.1|4668108_4669011_+|AraC-family-transcriptional-regulator
MQTRYTDLAAKLARHVTAPGITPSPVDQVSLIYTTEYHGRTPVLYQPRMIVILQGHKVGYLADQVFRYDPNHYLLMTLPLPCECECFASPEQPLIGFSLEINLVTLQELLLELGDALPAPTPQKSGVHSVPLSEAMFCAAERLIDLMDKPHHARVLGPQTVREMLFYALHEGGGPALQALANRHNHVGQIARVLRMIESRYADNLTMEELAREVNMSVSAFHHHFKAVTATSPLQYIKSFRLHKARMMMLHDGIKAGTAATRVGYESNSQFSREYKRFFGSTPTDQASRFREGQLRIIEG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP010947_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010947_9

4778919-4779049

Orphan

Consensus_repeat	Method
GTCTATCTCAAGCGCAAGGCAGGTTGATGTCACAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010947_9

>merge|NZ_CP010947|9|4778919-4779049|CRISPRCasFinder
GTCTATCTCAAGCGCAAGGCAGGTTGATGTCACAGGGGAGAGCACGTCGCCCTGTCCGAACCACTTCCCCCTGGGTTCACGACATGGAAGCCGGCGTCTATCTCAAGCGCAAGGCAGGCTGATGTCACAGG

>NZ_CP010947|9|9|4778919-4779049|CRISPRCasFinder
GTCTATCTCAAGCGCAAGGCAGGTTGATGTCACAGG	GGAGAGCACGTCGCCCTGTCCGAACCACTTCCCCCTGGGTTCACGACATGGAAGCCGGC
GTCTATCTCAAGCGCAAGGCAGGCTGATGTCACAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010947.1\|WP_010635722.1\|4781392_4781575_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044801076.1\|4780012_4781338_+\|two-component-system-sensor-histidine-kinase-RstB	unknown	unknown	gnl\|CDD\|236724
NZ_CP010947.1\|WP_044801067.1\|4769087_4770383_+\|DUF115-domain-containing-protein	unknown	unknown	gnl\|CDD\|376693
NZ_CP010947.1\|WP_044801072.1\|4773119_4773884_-\|AAC(3)-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|376807
NZ_CP010947.1\|WP_044801253.1\|4779184_4779895_+\|two-component-system-response-regulator-RstA	unknown	unknown	gnl\|CDD\|236738
NZ_CP010947.1\|WP_044801078.1\|4787340_4788465_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_016352348.1\|4784690_4784906_-\|50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234576
NZ_CP010947.1\|WP_044801070.1\|4771367_4772729_-\|DUF4910-domain-containing-protein	unknown	unknown	gnl\|CDD\|381731
NZ_CP010947.1\|WP_044801073.1\|4774097_4775780_-\|HAD-IIIC-family-phosphatase	unknown	unknown	gnl\|CDD\|226399
NZ_CP010947.1\|WP_044801068.1\|4770379_4770640_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010947.1\|WP_044801071.1\|4772725_4773130_-\|glyoxalase	unknown	unknown	gnl\|CDD\|319912
NZ_CP010947.1\|WP_044801074.1\|4776498_4777641_-\|DUF5610-domain-containg-protein	unknown	unknown	gnl\|CDD\|375859
NZ_CP010947.1\|WP_029304963.1\|4775877_4776411_-\|ATP--cob(I)alamin-adenosyltransferase	unknown	unknown	gnl\|CDD\|213544
NZ_CP010947.1\|WP_043126011.1\|4783089_4784523_-\|DUF2867-domain-containing-protein	unknown	unknown	gnl\|CDD\|187556
NZ_CP010947.1\|WP_044801069.1\|4770639_4771386_+\|crotonobetainyl-CoA--carnitine-CoA-transferase	unknown	unknown	gnl\|CDD\|379276
NZ_CP010947.1\|WP_044801079.1\|4788517_4789072_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP010947.1\|WP_044801080.1\|4789152_4789602_+\|HPP-family-protein	unknown	unknown	gnl\|CDD\|377434
NZ_CP010947.1\|WP_024945539.1\|4773880_4774105_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|223314
NZ_CP010947.1\|WP_044801077.1\|4781651_4782908_-\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|235976
NZ_CP010947.1\|WP_080891488.1\|4785053_4787261_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514

Protein	Function_ID	Function_description	E-value
NZ_CP010947.1\|WP_044801073.1\|4774097_4775780_-\|HAD-IIIC-family-phosphatase	gnl\|CDD\|226399	COG3882, FkbH, Predicted enzyme involved in methoxymalonyl-ACP biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	9.8197e-85
NZ_CP010947.1\|WP_044801067.1\|4769087_4770383_+\|DUF115-domain-containing-protein	gnl\|CDD\|376693	pfam01973, MAF_flag10, Protein of unknown function DUF115. This family of archaebacterial proteins has no known function.	2.67143e-36
NZ_CP010947.1\|WP_044801072.1\|4773119_4773884_-\|AAC(3)-family-N-acetyltransferase	gnl\|CDD\|376807	pfam02522, Antibiotic_NAT, Aminoglycoside 3-N-acetyltransferase. This family consists of bacterial aminoglycoside 3-N-acetyltransferases EC:2.3.1.81, these catalyze the reaction: Acetyl-Co + a 2-deoxystreptamine antibiotic <=> CoA + N3'-acetyl-2-deoxystreptamine antibiotic. The enzyme can use a range of antibiotics with 2-deoxystreptamine rings as acceptor for its acetyltransferase activity, this inactivates and confers resistance to gentamicin, kanamycin, tobramycin, neomycin and apramycin amongst others.	1.86363e-44
NZ_CP010947.1\|WP_044801253.1\|4779184_4779895_+\|two-component-system-response-regulator-RstA	gnl\|CDD\|236738	PRK10701, PRK10701, DNA-binding transcriptional regulator RstA; Provisional.	8.51504e-157
NZ_CP010947.1\|WP_016352348.1\|4784690_4784906_-\|50S-ribosomal-protein-L31	gnl\|CDD\|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	2.31445e-38
NZ_CP010947.1\|WP_044801070.1\|4771367_4772729_-\|DUF4910-domain-containing-protein	gnl\|CDD\|381731	cd05644, M28_like, M28 Zn-peptidase-like, uncharacterized subfamily. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They typically have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. Proteins in this subfamily conserve some of the metal-coordinating residues of the typically co-catalytic M28 family, and appear to bind a single metal (Zn) ion.	0
NZ_CP010947.1\|WP_044801076.1\|4780012_4781338_+\|two-component-system-sensor-histidine-kinase-RstB	gnl\|CDD\|236724	PRK10604, PRK10604, sensor protein RstB; Provisional.	0
NZ_CP010947.1\|WP_044801071.1\|4772725_4773130_-\|glyoxalase	gnl\|CDD\|319912	cd07249, MMCE, Methylmalonyl-CoA epimerase (MMCE). MMCE, also called methylmalonyl-CoA racemase (EC 5.1.99.1) interconverts (2R)-methylmalonyl-CoA and (2S)-methylmalonyl-CoA. MMCE has been found in bacteria, archaea, and in animals. In eukaryotes, MMCE is an essential enzyme in a pathway that converts propionyl-CoA to succinyl-CoA, and is important in the breakdown of odd-chain length fatty acids, branched-chain amino acids, and other metabolites. In bacteria, MMCE participates in the reverse pathway for propionate fermentation, glyoxylate regeneration, and the biosynthesis of polyketide antibiotics. MMCE is closely related to glyoxalase I and type I extradiol dioxygenases.	4.64415e-21
NZ_CP010947.1\|WP_044801074.1\|4776498_4777641_-\|DUF5610-domain-containg-protein	gnl\|CDD\|375859	pfam18433, DUF5610, Domain of unknown function (DUF5610). This is a domain of unknown function found in bacterial proteins.	1.47687e-27
NZ_CP010947.1\|WP_029304963.1\|4775877_4776411_-\|ATP--cob(I)alamin-adenosyltransferase	gnl\|CDD\|213544	TIGR00636, PduO_Nterm, ATP:cob(I)alamin adenosyltransferase. This model represents as ATP:cob(I)alamin adenosyltransferase family corresponding to the N-terminal half of Salmonella PduO, a 1,2-propanediol utilization protein that probably is bifunctional. PduO represents one of at least three families of ATP:corrinoid adenosyltransferase: others are CobA (which partially complements PduO) and EutT. It was not clear originally whether ATP:cob(I)alamin adenosyltransferase activity resides in the N-terminal region of PduO, modeled here, but this has now become clear from the characterization of MeaD from Methylobacterium extorquens. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	1.78905e-16
NZ_CP010947.1\|WP_043126011.1\|4783089_4784523_-\|DUF2867-domain-containing-protein	gnl\|CDD\|187556	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2. This subgroup contains atypical SDRs, one member is identified as Escherichia coli protein ybjT, function unknown. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif consensus that generally matches the extended SDRs, TGXXGXXG, but lacks the characteristic active site residues of the SDRs. This subgroup has basic residues (HXXXR) in place of the active site motif YXXXK, these may have a catalytic role. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.51503e-109
NZ_CP010947.1\|WP_044801069.1\|4770639_4771386_+\|crotonobetainyl-CoA--carnitine-CoA-transferase	gnl\|CDD\|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	0.000107621
NZ_CP010947.1\|WP_044801079.1\|4788517_4789072_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	5.54187e-14
NZ_CP010947.1\|WP_044801080.1\|4789152_4789602_+\|HPP-family-protein	gnl\|CDD\|377434	pfam04982, HPP, HPP family. These proteins are integral membrane proteins with four transmembrane spanning helices. The most conserved region of the alignment is a motif HPP. The function of these proteins is uncertain but they may be transporters.	5.1205e-28
NZ_CP010947.1\|WP_024945539.1\|4773880_4774105_-\|acyl-carrier-protein	gnl\|CDD\|223314	COG0236, AcpP, Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	0.000303291
NZ_CP010947.1\|WP_044801077.1\|4781651_4782908_-\|malate-dehydrogenase	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NZ_CP010947.1\|WP_080891488.1\|4785053_4787261_+\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0

>NZ_CP010947.1|WP_044801074.1|4776498_4777641_-|DUF5610-domain-containg-protein
MQIDGVGAAQPKGVGVAPKSPQQADSKPVNNEDEVSLHKAPKWAQVLVQQALQFALEINGQGYKAPKAQDQPEAVTPDTLFDFQSVADNVLQFVTGRLGAARADGKSDDSLAGMMEQARKGVDKGFGDARKQLGDWADNSDIKTGMDQSYKLIQEGLDQFEKEFFGKVSTTDMGQAEMASRQQGSLEIQTKDGDKVVLRFNDSWQTKSQKDDSGSQFSLKSSQSFSFSLEGNLSSEEMDSIGKLVKGLDDLAGNFFSGNFDDLLKKAGELKLDDSQLASYSLKLKQSLKLSQTYQGAHSLQEMLKPLADYLPKLDQVQQQADSLLPASQQQALTPAVLAARGQSDPAQVGSFTSFNQRMLDALRMIGQFQPATDASSKSV
>NZ_CP010947.1|WP_029304963.1|4775877_4776411_-|ATP--cob(I)alamin-adenosyltransferase
MNPKKPRDKRELCYPFIFETQFQCDYEIATDELCCQVGAVLSHLAPDAEIAPMQADLAALQRLIYNLNGSVRGRLGIFEEDLAWLKGRYDHYNEASRGRVTGFVLPQGPQPIPTLHLCRCGSKKVVRLLVRLEESGVRFDPILYRFANLLANFFFVLTVYLKQLWQVDEVPYVSINY
>NZ_CP010947.1|WP_044801073.1|4774097_4775780_-|HAD-IIIC-family-phosphatase
MTMLHLSGSSFLMPGNLAWRPLAEYGEVQVAPHGQWLQTLMHQSADAAAGTHIIIWLWEDLVPARTLQEWGRLAQDDQQLAVAAFVDALCQPLLQHLQRRPQDHLLVGACSHAPLCVYGPAPAVLAALASAFEQQMARLRLQQPGLDDLHLPLWLQQHGRQHCFDRRNLYLMSCPFSMAGLASLAQWILPLLQRLQQPAHKVLVLDCDNTLWGGVVGEDGVGGVLLGQDGMGRLYQAFQQAASHWHGQGIVLALCSKNLADDVWRLFDEHPGMVLTRAQIAAAEIGWEPKSQGLRRLAARLNVGLDSLVFWDDSELERAEVRANCLEVMVMTPPADLWSWPDALLTLPALCSRHQSRDDGLRQHSYQAQAEAEAVRQQLGDEHAFLRQLALQADWQPLSPGNQLRAEQLSQKTNQFNLSGRRYQAAELARLASEGGDVWLAGLRDRFADHGMTALLVVRPLDEGRALLDTLAISCRVLGRGFDYWLLAQLANHLRAQGVTELVISLVATTRNQPARDFLASLPTRPITTPAGLLPLADEVFLSLDLCSLSLPFLEFYANE
>NZ_CP010947.1|WP_024945539.1|4773880_4774105_-|acyl-carrier-protein
MNDLIALAHQQFPQASVNAQSALGSFPEWDSLGHFNLLLLVEQHYAVRFEPHELAELKSLADIQQALLRKGVAV
>NZ_CP010947.1|WP_044801072.1|4773119_4773884_-|AAC(3)-family-N-acetyltransferase
MKQALEQALTELGIPRGGALMVHSDAMVVAQFAGMGNAEGIAAFWTCLEQWLGGHLLVPTFSYSPMAGECFDPAQTPSKVGLMTELFRQREGVVRTRDPVFSMAISGPQGPALVARECHDCFGQESPFGWLAEQDGWLLGLGCHPDRITFTHYVEQRLAVSYRYHKMFAGQVRVDCRVREWQADYYVRDLSLASEIDLSRLVALLQERGAWRQTQCQRVPVWAVSCRDFILAASELLAAAPYALIRAGGESHAV
>NZ_CP010947.1|WP_044801071.1|4772725_4773130_-|glyoxalase
MQFDHIGLVVPDLASGVAYCRDVLGLSRFSAAVEDPVQRVWVQFVHDEHGLCYELVAPAGEESPVAQVLKTRRNVINHLAYRVSNLQESAERLRTQRHLPLGASQPAIAFGGAHVQFFLSPLGHIVELIEAPTP
>NZ_CP010947.1|WP_044801070.1|4771367_4772729_-|DUF4910-domain-containing-protein
MSFLPKSGYLPTDWDDQAQIGEQLHRLLTLLFPLNRSLTGDGVRQSLALWREHCLPELQIHEVASGTECFDWTVPDEWNVREAYIVGPDGRRVVDFQDHNLHLVGYSEPVRCTLSLAELQPHLHSLPEQPDAIPYVTSYYKRRWGFCLPHRLREALPEGEYQVVIDATLAPGSLTYGDWVLPGESEQEILLSSYTCHPSMANNELSGPCVGVFLMAWLASLPTRRYSYRLMLVPETLGAIVYLSRHLEQLKQRTLAGFNLTCLGDDRSYSFLPSRQGNTLADRIGRHVLGHLAPGYQAYSFLERGSNERQLCAPGIDLPVTSVMRSRYGCYAEYHTSLDDLSLVTPAGLAGGFMALRRAIECLELDERCEVTVLGEPQLGKRGLYPDLSTRYSGWQVREMMNLLAYSDGKLTLFEIAETIGAPFWRVEPLARMLLDAGLLRRLSPQPDYSITR
>NZ_CP010947.1|WP_044801069.1|4770639_4771386_+|crotonobetainyl-CoA--carnitine-CoA-transferase
MIKAISNASEQELSRRQTFSELLHTSPLPAAELQNNLGLYLKRQSLSRILFMHELYQKIVPVHGVIMDFGTRWGQNLALFSSFRGMYEPYNYNRKLVGFDTFSGFPSHAPQDGSDAAIQPGAYGVTPGYEQHLTQLLAAHEAESPLDHIVKHELVKGDVTETLPAYLARQPETMVALAYFDFDLYEPTRRCLELIKPHLTKGSVLAFDELNWPAFPGETLALKEVLGLDRYAIRRTPHNPGPAYLVIE
>NZ_CP010947.1|WP_044801068.1|4770379_4770640_+|hypothetical-protein
MKNGQITRLTALAHQFRLGQSVAASQALPELLQAVLTEQGNLPPGLVAALLQCQERQDWLGLADYLEYEVVHYLSTPAGDTTTGDH
>NZ_CP010947.1|WP_044801067.1|4769087_4770383_+|DUF115-domain-containing-protein
MSDDLFNQHGRLISQRWPALWPRLLAQDVESLPAELTEGLGSTLSLHGIQLTSRHDRVKEAELQAASLPEQPVLHLYGTGLGDLPRALLGRSSLKRLEVKIMNGALFALVLRLLDQQDWLTDPRVELMMAGDEGEVRLPFFALPPELLLVENAAARIRDRLVSEIDLPFARARFDAEHPDVTRRLAENRDLLAGDGDVASLFGLAQGKQALIVASGPTLQHNLATLQAQLQRRRQDYLLISVDTALAFLLGHGIRPDIVVTIDDAIDGNRLPAAQSAQTTLVYYPTVPTAALLAWQGPRKTAYSRSPMYQQLRQTLPKGVLHSGGSVIHPAVDLAVQMGCRQVILLGTDFAFPGELTHSGWADGALGPSAALALSWALDGHGRRVKTNPNFSAYRTELERYIARHPEVQFWNCSREGAEIAGCRYHPEYVQ
>NZ_CP010947.1|WP_044801253.1|4779184_4779895_+|two-component-system-response-regulator-RstA
MQRILFVEDDPEIGQLISSWLARHDMEVLLEPRGDLALARVEAEQPDLVLLDIMLPGQDGLSLCRDLRPRFAGPIVMLTSLDSDMNQILSLELGANDYILKTTPPPVLLARLRVQFRQQGQQVPQPVVASTPPQRLQFGRLQIDGPGRDVRLDGDSIPLSTADFDLLWELACHAGQILGREALFRSLRGRDYDGQDRSMDVAISRLRRKLGDDTSNPTRIKTVRQKGYLLVPQAWE
>NZ_CP010947.1|WP_044801076.1|4780012_4781338_+|two-component-system-sensor-histidine-kinase-RstB
MRRLFIQFYLLLIGCFTLAILLVGMVYQVTAERAGDRYLERMMQGSLGLLTGELARLPPEHWPARMAEQSRQLTLPLQIGALANQPLANEDQAFLEAGNIVIVEEDDTFLQRIPGTDQVLIVGPVPYLSYLHELHWVDVGLLLVIGLSLGLPILLWLRPHWRGLQQLEQTARRVGDGDLSCRTRLPPGSSLGRVGRTFDQMTEQLQAMLASRKQLTDAIAHELRTPLVRLRYRLAMLDPAPSAEEQQGLERDLGALDALIEEMLTYARLDRPELPLQCSELELGSWAGSRLADWQALRPDKRLDFVRPAMALPWRGDTRLLDRALENLIGNALRHAASRVTLSMACQQDHYLLEVADDGVGIDPALAPQIFEPFVRLDQSRDRRTGGAGLGLAIVRSIARHHGGEVQLLPSSSGARFCLMLPVHLDTNRHQSLTEPQVEQP
>NZ_CP010947.1|WP_010635722.1|4781392_4781575_+|hypothetical-protein
MNKLIPLSLAAVFALTSGFTMAATPTKAAAPQATQTKVVKKHHKAAHAKAPAVKVAPKTK
>NZ_CP010947.1|WP_044801077.1|4781651_4782908_-|malate-dehydrogenase
MSDQRHDLRQQALDYHAQPVPGKIAIALTKPAETARDLALAYSPGVAEPVREIAANPADAYRYTGKGNLVAVISNGTAILGLGNLGPLASKPVMEGKALLFKRFAGIDAIDIEVKHETSAQFIDTVAAIADTFGGINLEDIKAPECFEIEQALIERCDIPVFHDDQHGTAIVTAAGLLNALEVQGKQIGDSRIVCMGAGAAATACMELLIKCGAKPHNIFMLDRQGVIHSGRTDLNQYKQRFANDTPLRTLMEVIDGADVFVGVSGPDVLPAEAVALMAPNPVIFACSNPDPEIKPALAHAVRKDLIMGTGRSDYPNQINNVLCFPFIFRGALDARASRINDAMKIAAVEAIRGLAKEPVPAEVLTAAGVGELAFGKDYVIPKPMDARLLPRVARAVALAAVESGVARIALPADYMLG
>NZ_CP010947.1|WP_043126011.1|4783089_4784523_-|DUF2867-domain-containing-protein
MRDCLVMGAAGYIGSYLVPHLQELGYRVIAGARRPCRLPPGVEFRLADSLKPITLLPALAGIDTVFYLVHAMGAGADFHRLEQQGVKNFAAAARAAGVRRIIYLGAIQPAQCNSRHLNSRRYCGELFRGAGVPTVELRAGIIVGPGSAAFEVMRDLVFNLPMMVTPKWVRSRTPPIALSNLLHYLGGLVEADGVDGQIFNAAGPELLSYQQQLQKFAAHIGKRCPIIPLPFLSPRLSAWWLQFVTSVPQPVAKALVGGLKHDIPADDGPLRALLPQTLLSFDEALAESLSLEQQLGAEQQGEETPLGLRWRHPEYGFYDRTASGDAICLASPEVVWQVLQQLGGEQRYFYMNQLWVVREWMDHLIGGPALTRGRTNPDRFVKGDMLDSWQILGVDEGRRLDLLFNMRAPGVGRLEFNILPEESGLTRLKVTAHWHPQGAWGLAYWLAMLPFHLFIFQGMTEAIARQAEAKAGIPVMG
>NZ_CP010947.1|WP_016352348.1|4784690_4784906_-|50S-ribosomal-protein-L31
MKAGIHPDYVAITAKCSCGNVINTFSTLGKDLNLDVCSECHPFYTGKQKEVSSGGRVDKFNKRFGAMTTKK
>NZ_CP010947.1|WP_080891488.1|4785053_4787261_+|primosomal-protein-N'
MNSSQTLDLVRVAVPVPLRRHFDYLSPLPLPAPGCRVEIPFGPQTLVGLVVDHPADSQVPRNKLKPIKRVLDSAPVLGPDILALMNWSASYYQHPLGEVLPHALPVLVRKGEPAAYRELEFWFATEAGMAVDLNELKRAAKQQQALALLRKGPQTPSALKQEEIQSAALTALEKKGLLEKRSLEPSHDGDWVARFEPGEGLRLNGEQALAVSAVTSQSDQFGAFLLDGITGSGKTEVYLSILEPLLKAGKQALVMVPEIGLTPQTINRFRRRFNVPVVAMNSAMNDRERLDAWLACRDGGAAILIGTRSAVFTPFHNLGIIIIDEEHDGSFKQQDGFRYHARDLAVMRAHRAGIPILLGSATPSLETLHNARSGKYHHLTLTRRAGNAQTARQVILDIKNVRLQAGLSPQLEQLMAEHLAAGNQVMLFLNRRGYAPALICHQCGWSAACERCDAWYTWHQAGRRLHCHHCDSVRPLPHHCPECGSNELIGSGVGTEQLEQLLGTVFPQYPVVRIDRDNTRRKGELETHLGDIKAGKYKILIGTQMLAKGHHFPDVTLVGLLDVDGALFSADFRAAEKLAQLYTQVAGRAGRASKPGLVVLQSHHPEHALLQDLTQNGYGHFADTALKERRLLGLPPFSYQGLFRAEANGRDEVQLFLSRLADTLRSARYPHVQVLGPISGFMERKAGKFRMQLLVQGPNRAPLAQLLDWAVKELEGWPETKRVRWSLDIDPTELN
>NZ_CP010947.1|WP_044801078.1|4787340_4788465_-|hypothetical-protein
MYGAEGEDMRIDHYDLQGEVQYLQQQAQSRKVRRLGPVPAASQAQSPATAPADSTPAAGGGSQLTFTRSSLLTLQMASRTATGPVPAAPTPTPAKPAETGKGEQDGIPNDGLDNRQRLIKLMIEAMLGHEIELPDPIKPADQSAEGVPVPTGEGTQPAAEPDQLVEVTDSLLQKEQLNVVAAANLQTQDGQTLQLDLGFVLDWRQLDISQRRTTLNALKDPLVLSLDGKIAGLTDARVNFDIDQDGKADSLPGLSEGSGFVALDRNGNGTIDDGGELFGARSGNGFGELATLDEDGNGVMDERDSQFSALQFWQPEQSPIALVELGIGAILLHPLDTPFNHLGESGNQGVLRQSGLYVTEQGKGGWVQQVDLRV
>NZ_CP010947.1|WP_044801079.1|4788517_4789072_-|TetR/AcrR-family-transcriptional-regulator
MSEKRQQLMETAYRLFNRHGFHATGIDRIWAEAGSTKRTLYRHFPTKDALIEEVLQSREREFFALLEERQQGLEGRESRLHALFDGFGEWFARSDFYGCNFINASAEFADPRHPVRKLVVAHKQALLDWVCTRLECDQTQATGICLLLEGAVVMAHSYQQPLALVQARSLALALLCANGEVTAP
>NZ_CP010947.1|WP_044801080.1|4789152_4789602_+|HPP-family-protein
MRRWYGPLWAGVGAALAIGVLGGLNISWHGALIMAPFGASCVLLFSLPTSPLARPWNVLGGHLLTTAVGLLVQGLPLPLVAQLALGVGLAIALMQGLNLIHPPAGANPLLVLMTGQQWPFLWHTVLPGALLLILLGYGFQRVKWRLGTG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP010947_1	1.1\|1100176\|26\|NZ_CP010947\|CRISPRCasFinder	1100176-1100201	26	NZ_AP014810	Methylorubrum populi strain P-1M plasmid pMPPM01, complete sequence	36214-36239	3	0.885
NZ_CP010947_1	1.1\|1100176\|26\|NZ_CP010947\|CRISPRCasFinder	1100176-1100201	26	NZ_CP049702	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2c, complete sequence	151819-151844	4	0.846
NZ_CP010947_1	1.1\|1100176\|26\|NZ_CP010947\|CRISPRCasFinder	1100176-1100201	26	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	106482-106507	4	0.846
NZ_CP010947_1	1.1\|1100176\|26\|NZ_CP010947\|CRISPRCasFinder	1100176-1100201	26	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	283431-283456	4	0.846
NZ_CP010947_1	1.1\|1100176\|26\|NZ_CP010947\|CRISPRCasFinder	1100176-1100201	26	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	435315-435340	4	0.846
NZ_CP010947_1	1.1\|1100176\|26\|NZ_CP010947\|CRISPRCasFinder	1100176-1100201	26	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	622106-622131	4	0.846
NZ_CP010947_1	1.1\|1100176\|26\|NZ_CP010947\|CRISPRCasFinder	1100176-1100201	26	NZ_CP035513	Haematobacter massiliensis strain OT1 plasmid pOT1-3, complete sequence	144139-144164	5	0.808

1. spacer 1.1|1100176|26|NZ_CP010947|CRISPRCasFinder matches to NZ_AP014810 (Methylorubrum populi strain P-1M plasmid pMPPM01, complete sequence) position: , mismatch: 3, identity: 0.885

cgtggtggaaacggtgcggctgatgt	CRISPR spacer
cggggtggaaacggtgcggctgagtt	Protospacer
** ********************  *

2. spacer 1.1|1100176|26|NZ_CP010947|CRISPRCasFinder matches to NZ_CP049702 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2c, complete sequence) position: , mismatch: 4, identity: 0.846

cgtggtggaaacggtgcggctgatgt	CRISPR spacer
cgccctggaaacggtgcggctgatga	Protospacer
**.  ********************

3. spacer 1.1|1100176|26|NZ_CP010947|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 4, identity: 0.846

cgtggtggaaacggtgcggctgatgt	CRISPR spacer
catggtggaggcggtgcggctgatgc	Protospacer
*.*******..**************.

4. spacer 1.1|1100176|26|NZ_CP010947|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 4, identity: 0.846

cgtggtggaaacggtgcggctgatgt	CRISPR spacer
catggtggaggcggtgcggctgatgc	Protospacer
*.*******..**************.

5. spacer 1.1|1100176|26|NZ_CP010947|CRISPRCasFinder matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 4, identity: 0.846

cgtggtggaaacggtgcggctgatgt	CRISPR spacer
catggtggaggcggtgcggctgatgc	Protospacer
*.*******..**************.

6. spacer 1.1|1100176|26|NZ_CP010947|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 4, identity: 0.846

cgtggtggaaacggtgcggctgatgt	CRISPR spacer
catggtggaggcggtgcggctgatgc	Protospacer
*.*******..**************.

7. spacer 1.1|1100176|26|NZ_CP010947|CRISPRCasFinder matches to NZ_CP035513 (Haematobacter massiliensis strain OT1 plasmid pOT1-3, complete sequence) position: , mismatch: 5, identity: 0.808

cgtggtggaaacggtgcggctgatgt	CRISPR spacer
gcgggcggaaacggtgcggctgatgg	Protospacer
   **.*******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

41222 : 114911

Salmonella_phage(20.51%)

portal,tail,capsid,plate,tRNA,head,lysis,terminase,integrase,holin

attL 80115:80135|attR 114975:114995

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026080420.1\|41222_41954_-\|tRNA	tRNA (guanosine(18)-2'-O)-methyltransferase TrmH	NA	NA	NA	NA
WP_011704079.1\|42178_44296_-	bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase	A0A291L9W9	Bordetella_phage	6.1e-13	37.6
WP_005307060.1\|44433_44709_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_016348898.1\|44788_45415_-	guanylate kinase	K4JYM5	Abalone_herpesvirus	1.1e-23	37.4
WP_044801127.1\|45686_46769_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_044798708.1\|46923_47637_+	3-deoxy-D-manno-octulosonic acid kinase	NA	NA	NA	NA
WP_044798709.1\|47707_48571_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_011704084.1\|48578_49433_-	DMT family transporter	NA	NA	NA	NA
WP_044798710.1\|49476_49935_+	hypothetical protein	NA	NA	NA	NA
WP_016348905.1\|50219_51119_-	EamA family transporter	NA	NA	NA	NA
WP_011704088.1\|51210_52185_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_044798711.1\|52163_53177_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_044798712.1\|53368_53809_-	universal stress protein	NA	NA	NA	NA
WP_044798716.1\|54275_55463_+	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_044798717.1\|55478_57269_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.1e-15	36.8
WP_016348910.1\|57478_58003_+	non-heme ferritin	NA	NA	NA	NA
WP_162484572.1\|58086_59271_+	aminoacetone oxidase family FAD-binding enzyme	NA	NA	NA	NA
WP_044798720.1\|59457_60678_-	MFS transporter	NA	NA	NA	NA
WP_044798721.1\|60953_61592_+	leucine efflux protein LeuE	NA	NA	NA	NA
WP_044798722.1\|61635_62322_-	molecular chaperone	NA	NA	NA	NA
WP_162484562.1\|62324_63950_-	hypothetical protein	NA	NA	NA	NA
WP_052508915.1\|63949_66427_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_044798724.1\|66478_67144_-	hypothetical protein	NA	NA	NA	NA
WP_044798725.1\|67203_67782_-	fimbrial protein	NA	NA	NA	NA
WP_044798726.1\|68382_69006_+	response regulator transcription factor	NA	NA	NA	NA
WP_044798727.1\|69008_72596_+	transporter substrate-binding domain-containing protein	A0A1V0SGX0	Hokovirus	7.8e-37	32.5
WP_024945882.1\|72631_73072_-	hypothetical protein	NA	NA	NA	NA
WP_044798728.1\|73244_74918_+	sensor histidine kinase	NA	NA	NA	NA
WP_044798729.1\|74964_75696_+	response regulator transcription factor	NA	NA	NA	NA
WP_044798730.1\|75805_76996_+	MFS transporter	NA	NA	NA	NA
WP_044798731.1\|77070_78195_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_011704108.1\|78191_78701_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.6e-18	40.0
WP_005306985.1\|78763_79066_-	hypothetical protein	NA	NA	NA	NA
WP_044798732.1\|79070_79997_-	sodium-dependent bicarbonate transport family permease	NA	NA	NA	NA
80115:80135	attL	NA	NA	NA	NA
WP_144406105.1\|80230_81343_-	phage late control D family protein	E5E3P7	Burkholderia_phage	7.9e-97	56.0
WP_044798736.1\|81378_81873_-\|tail	tail assembly protein	E5G6Q2	Salmonella_phage	2.7e-33	57.1
WP_044798737.1\|81885_84345_-\|tail	phage tail tape measure protein	A0A1S6L010	Salmonella_phage	7.0e-162	40.3
WP_044798738.1\|84341_84473_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_039214151.1\|84481_84766_-\|tail	phage tail assembly protein	E5FFG6	Burkholderia_phage	1.4e-10	45.3
WP_044798739.1\|84845_85364_-\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	4.2e-53	57.0
WP_044798740.1\|85373_86552_-\|tail	phage tail sheath protein	F1BUU3	Erwinia_phage	2.7e-135	62.0
WP_044798741.1\|86735_87143_-\|tail	tail fiber assembly protein	B0VK51	Azospirillum_phage	5.4e-11	50.0
WP_044798742.1\|87153_88182_-	DNA inversion product	A0A1I9KF43	Aeromonas_phage	1.1e-60	62.5
WP_044798743.1\|88178_88811_-\|tail	phage tail protein I	A0A0F7LA36	Escherichia_phage	1.6e-65	60.6
WP_044798744.1\|88807_89707_-\|plate	baseplate assembly protein	Q9ZXK8	Pseudomonas_virus	8.4e-89	57.5
WP_044798745.1\|89703_90063_-\|plate	baseplate assembly protein	A4PE42	Ralstonia_virus	1.2e-22	57.1
WP_044798746.1\|90059_90632_-\|plate	phage baseplate assembly protein V	F1BUP5	Erwinia_phage	6.0e-24	40.2
WP_080891176.1\|90773_91415_-	phage virion morphogenesis protein	F1BUP7	Erwinia_phage	8.0e-09	40.5
WP_044798748.1\|91396_91867_-\|tail	phage tail protein	F1BUP9	Erwinia_phage	1.7e-32	46.6
WP_044798749.1\|91977_92445_-\|lysis	phage lysis regulatory protein LysB	E5G6N2	Salmonella_phage	5.4e-07	34.5
WP_044798751.1\|92595_93414_-	DUF3380 domain-containing protein	A0A2H4JGJ9	uncultured_Caudovirales_phage	2.2e-67	53.3
WP_044798752.1\|93410_93719_-\|holin	phage holin family protein	G9L6E7	Escherichia_phage	7.9e-07	38.0
WP_044798753.1\|93720_93981_-	hypothetical protein	NA	NA	NA	NA
WP_044798755.1\|93982_94348_-	membrane protein	A0A1S5NRL1	Burkholderia_phage	1.6e-14	43.4
WP_049828121.1\|94363_94606_-	conjugal transfer protein TraR	A0A1S6L007	Salmonella_phage	3.4e-05	38.0
WP_017765313.1\|94596_94800_-\|tail	tail protein	A0A2H4J946	uncultured_Caudovirales_phage	2.8e-16	59.1
WP_005308743.1\|94799_95270_-\|head	head completion/stabilization protein	E5E3S2	Burkholderia_phage	1.2e-30	49.0
WP_044798756.1\|95379_96063_-\|terminase	terminase	A4PE31	Ralstonia_virus	6.6e-46	45.3
WP_044798757.1\|96072_97125_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	2.0e-110	56.8
WP_044798758.1\|97137_97968_-\|capsid	GPO family capsid scaffolding protein	E5FFI7	Burkholderia_phage	3.1e-53	46.1
WP_044798759.1\|98116_99886_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	4.4e-235	67.7
WP_080891177.1\|99882_100947_+\|portal	phage portal protein	A4PE27	Ralstonia_virus	1.2e-115	57.4
WP_052508916.1\|101793_102159_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_044798761.1\|102677_102866_-	DUF3283 family protein	NA	NA	NA	NA
WP_044798762.1\|103354_103696_-	hypothetical protein	A0A219YA08	Aeromonas_phage	1.8e-15	43.8
WP_044798763.1\|103692_104043_-	hypothetical protein	NA	NA	NA	NA
WP_044798764.1\|104035_104440_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	6.1e-15	54.8
WP_044801131.1\|104424_105081_-	hypothetical protein	Q1MVG0	Enterobacteria_phage	6.2e-25	35.2
WP_044798765.1\|105128_105356_-	hypothetical protein	NA	NA	NA	NA
WP_044798767.1\|105366_107769_-	replication endonuclease	A5X9G4	Aeromonas_virus	4.6e-102	35.4
WP_044798768.1\|107750_108122_-	hypothetical protein	NA	NA	NA	NA
WP_044798769.1\|108199_108445_-	hypothetical protein	NA	NA	NA	NA
WP_044798770.1\|108441_108663_-	hypothetical protein	NA	NA	NA	NA
WP_044798771.1\|108962_109145_-	hypothetical protein	NA	NA	NA	NA
WP_044798772.1\|109141_109432_-	hypothetical protein	NA	NA	NA	NA
WP_044798774.1\|109512_109812_-	hypothetical protein	NA	NA	NA	NA
WP_139726060.1\|109953_110115_-	DUF3927 family protein	NA	NA	NA	NA
WP_044798775.1\|110107_110542_-	tellurite resistance TerB family protein	Q1MVI3	Enterobacteria_phage	2.8e-42	61.5
WP_044798776.1\|110578_111022_-	hypothetical protein	NA	NA	NA	NA
WP_044798777.1\|111037_111256_-	hypothetical protein	NA	NA	NA	NA
WP_080891178.1\|111252_111570_-	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_044798778.1\|111582_112095_-	phage protein	A5X9F7	Aeromonas_virus	1.1e-29	44.5
WP_044798779.1\|112122_112332_-	regulator for prophage	NA	NA	NA	NA
WP_044798781.1\|112514_113294_+	helix-turn-helix transcriptional regulator	A5X9F5	Aeromonas_virus	9.5e-57	47.4
WP_044798782.1\|113304_113844_+	hypothetical protein	NA	NA	NA	NA
WP_044798783.1\|113840_114911_+\|integrase	tyrosine-type recombinase/integrase	A0A0M4S6G4	Salmonella_phage	7.6e-105	56.4
114975:114995	attR	NA	NA	NA	NA

DBSCAN-SWA_2

958901 : 968838

uncultured_Mediterranean_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044799243.1\|958901_959648_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	2.1e-69	54.1
WP_011704775.1\|959652_960270_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.0e-34	46.4
WP_016349540.1\|960266_960848_+	DedA family protein	NA	NA	NA	NA
WP_044799244.1\|960858_961899_+	peptidoglycan DD-metalloendopeptidase family protein	A0A0A7NU10	Lactobacillus_phage	4.3e-12	35.1
WP_044799245.1\|961946_962930_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	1.7e-34	34.1
WP_024946180.1\|963015_964029_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	9.1e-108	58.3
WP_005309452.1\|964208_964424_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_044799246.1\|964439_964883_+	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	2.9e-26	48.6
WP_024946181.1\|964971_966759_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	5.2e-74	41.1
WP_073348937.1\|966972_968838_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-34	32.6

DBSCAN-SWA_3

1643019 : 1679052

Aeromonas_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044799561.1\|1643019_1646553_-	type I restriction-modification system endonuclease	A0A2I7QZ21	Vibrio_phage	1.2e-05	22.0
WP_044799562.1\|1646555_1647494_-	restriction endonuclease	NA	NA	NA	NA
WP_080891284.1\|1647764_1648910_-	DUF3596 domain-containing protein	I6PDJ1	Cronobacter_phage	5.4e-125	60.5
WP_017411491.1\|1648906_1649104_-	hypothetical protein	I6PBM8	Cronobacter_phage	3.3e-14	57.4
WP_044799564.1\|1649096_1649537_-	hypothetical protein	A0A1I9KG69	Aeromonas_phage	5.8e-51	85.4
WP_044799565.1\|1649593_1649842_-	hypothetical protein	NA	NA	NA	NA
WP_044799566.1\|1649944_1650559_-	hypothetical protein	H2BD40	Pseudomonas_phage	8.7e-05	37.6
WP_044799567.1\|1650555_1650861_-	DUF4406 domain-containing protein	A0A1I9KFD3	Aeromonas_phage	6.4e-41	91.3
WP_144406123.1\|1650864_1651578_-	hypothetical protein	A0A1I9KF90	Aeromonas_phage	2.0e-125	91.6
WP_044799569.1\|1651651_1651879_-	hypothetical protein	NA	NA	NA	NA
WP_044799570.1\|1651950_1652169_-	hypothetical protein	A0A1I9KF77	Aeromonas_phage	7.0e-34	97.2
WP_080891285.1\|1652132_1653308_-	DUF3850 domain-containing protein	A0A059T7N3	Listeria_phage	5.5e-16	61.1
WP_052508935.1\|1653304_1653883_-	hypothetical protein	A0A1I9KF82	Aeromonas_phage	5.8e-27	45.2
WP_052508936.1\|1653879_1654152_-	hypothetical protein	NA	NA	NA	NA
WP_044799571.1\|1654148_1655060_-	recombination-associated protein RdgC	A0A1I9KF67	Aeromonas_phage	8.2e-84	51.5
WP_044799572.1\|1655315_1655894_-	phage N-6-adenine-methyltransferase	A0A1I9KF87	Aeromonas_phage	1.8e-105	95.3
WP_044799573.1\|1655886_1656501_-	hypothetical protein	A0A076G7C3	Sinorhizobium_phage	1.3e-29	37.9
WP_044799574.1\|1656497_1657715_-	hypothetical protein	A0A1I9KG78	Aeromonas_phage	8.7e-174	79.2
WP_080891286.1\|1657765_1658881_-	hypothetical protein	A0A1I9KFA0	Aeromonas_phage	2.9e-99	92.6
WP_052508937.1\|1658926_1659904_-	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	2.6e-168	90.9
WP_044799576.1\|1659900_1660746_-	exodeoxyribonuclease VIII	A0A1I9KFF5	Aeromonas_phage	2.2e-160	94.0
WP_044799577.1\|1660742_1661105_-	hypothetical protein	NA	NA	NA	NA
WP_044799578.1\|1661101_1661467_-	hypothetical protein	A0A1I9KFC9	Aeromonas_phage	1.4e-34	63.6
WP_044799579.1\|1661469_1661661_-	hypothetical protein	A0A1I9KG01	Aeromonas_phage	3.4e-24	93.5
WP_052508938.1\|1661736_1662423_-	hypothetical protein	A0A0P0ZGC2	Escherichia_phage	3.8e-25	50.0
WP_144406124.1\|1662753_1663029_+	hypothetical protein	NA	NA	NA	NA
WP_044799580.1\|1663300_1663546_-	hypothetical protein	A0A1I9KF98	Aeromonas_phage	2.4e-30	85.2
WP_044799581.1\|1663845_1664025_-	hypothetical protein	NA	NA	NA	NA
WP_052508955.1\|1664660_1665245_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_044799583.1\|1665411_1665618_+	hypothetical protein	NA	NA	NA	NA
WP_034283244.1\|1665659_1666049_+	hypothetical protein	A0A1I9KF96	Aeromonas_phage	1.2e-47	81.4
WP_017411466.1\|1666053_1666272_+	hypothetical protein	A0A1I9KFG0	Aeromonas_phage	9.8e-28	90.3
WP_044799585.1\|1667429_1668842_+	AAA family ATPase	Q716D2	Shigella_phage	1.8e-101	44.4
WP_044799586.1\|1668834_1669146_+	hypothetical protein	A0A1I9KFB1	Aeromonas_phage	1.4e-38	80.8
WP_044799587.1\|1669223_1669517_+	hypothetical protein	A0A1I9KG94	Aeromonas_phage	3.4e-47	91.8
WP_158319750.1\|1669525_1669687_+	hypothetical protein	NA	NA	NA	NA
WP_044799588.1\|1669689_1670133_+	recombination protein NinB	A0A1I9KFA6	Aeromonas_phage	6.0e-72	91.7
WP_044799589.1\|1670129_1670789_+	hypothetical protein	A0A1I9KFG5	Aeromonas_phage	1.9e-119	93.6
WP_044799590.1\|1670785_1671103_+	DUF968 domain-containing protein	A0A1I9KFA7	Aeromonas_phage	1.2e-50	91.4
WP_044799591.1\|1671099_1671339_+	hypothetical protein	NA	NA	NA	NA
WP_044799592.1\|1671335_1671758_+	hypothetical protein	A0A1I9KG18	Aeromonas_phage	2.4e-62	80.7
WP_044799593.1\|1671754_1672366_+	hypothetical protein	NA	NA	NA	NA
WP_044799594.1\|1672483_1672828_+	hypothetical protein	NA	NA	NA	NA
WP_044799595.1\|1672824_1673019_+	DUF3283 family protein	NA	NA	NA	NA
WP_044799596.1\|1673042_1673264_+	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_044801180.1\|1673408_1673615_+	hypothetical protein	NA	NA	NA	NA
WP_044799597.1\|1673611_1674160_+	hypothetical protein	A2I317	Vibrio_virus	1.4e-49	56.8
WP_044799598.1\|1674167_1674392_+	hypothetical protein	A0A1I9KFG6	Aeromonas_phage	4.5e-20	65.8
WP_044799599.1\|1674388_1674571_+	hypothetical protein	A0A1I9KFC5	Aeromonas_phage	7.2e-08	54.5
WP_044799600.1\|1674697_1675285_+	hypothetical protein	A0A2L1IV66	Escherichia_phage	4.7e-08	32.0
WP_044799601.1\|1675274_1676843_+	hypothetical protein	A0A096XUU0	Cronobacter_phage	5.4e-75	35.3
WP_052508939.1\|1676847_1679052_+	hypothetical protein	W8FP98	Vibrio_phage	8.7e-39	28.8

DBSCAN-SWA_4

3823776 : 3831285

Staphylococcus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016351731.1\|3823776_3824247_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	3.5e-30	48.7
WP_044800624.1\|3824444_3825656_+\|protease	serine protease	V5LS29	Emiliania_huxleyi_virus	5.2e-09	26.9
WP_016351734.1\|3825719_3826829_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	7.9e-65	39.0
WP_044800625.1\|3826970_3827624_-	riboflavin synthase	A0A2I2L4R9	Orpheovirus	1.6e-20	36.1
WP_044800626.1\|3827678_3828788_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.6e-49	35.5
WP_010675395.1\|3828884_3829334_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_080891423.1\|3829468_3829948_-	hypothetical protein	NA	NA	NA	NA
WP_011707102.1\|3830031_3831285_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	2.3e-100	53.5

DBSCAN-SWA_5

4167094 : 4257994

Aeromonas_virus(62.5%)

portal,tail,capsid,tRNA,head,terminase,transposase,integrase,holin

attL 4192638:4192655|attR 4236714:4236731

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044800793.1\|4167094_4167805_+\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_080891590.1\|4167995_4169303_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_080891591.1\|4169639_4170974_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_029304812.1\|4171044_4171275_-	hypothetical protein	NA	NA	NA	NA
WP_016351979.1\|4171279_4171741_-	chemotaxis protein CheX	NA	NA	NA	NA
WP_011707398.1\|4171730_4172189_-	zinc uptake transcriptional repressor Zur	NA	NA	NA	NA
WP_044800797.1\|4172327_4173314_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_010636148.1\|4173541_4173967_-	hypothetical protein	NA	NA	NA	NA
WP_005305063.1\|4174068_4174341_-	DNA-binding protein HU-alpha	A0A249Y2G7	Serratia_phage	3.6e-11	44.2
WP_011707403.1\|4174681_4175164_+	Rsd/AlgQ family anti-sigma factor	NA	NA	NA	NA
WP_011707404.1\|4175265_4175646_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_011707405.1\|4175717_4177082_-	DNA repair protein RadA	NA	NA	NA	NA
WP_044800798.1\|4177182_4179561_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_044800799.1\|4179687_4180593_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_044800800.1\|4180642_4181653_-	phosphoserine phosphatase SerB	NA	NA	NA	NA
WP_044800801.1\|4181773_4182382_+\|transposase	transposase	NA	NA	NA	NA
WP_044800802.1\|4182435_4184682_+	PAS domain S-box protein	G3MA91	Bacillus_virus	2.3e-18	32.1
WP_011707410.1\|4184751_4185468_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_044800803.1\|4185545_4186754_-	phosphopentomutase	NA	NA	NA	NA
WP_011707412.1\|4186768_4188100_-	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	1.2e-78	39.8
WP_044800804.1\|4188210_4188984_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_005305103.1\|4189375_4189546_-	DUF1427 family protein	R4TMJ4	Halovirus	6.3e-06	60.0
WP_044800805.1\|4189669_4190944_-	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_044800806.1\|4191157_4191946_-	TatD family hydrolase	NA	NA	NA	NA
WP_044800807.1\|4191986_4192604_+	type II secretion system protein	NA	NA	NA	NA
WP_080891444.1\|4192572_4192755_-	hypothetical protein	NA	NA	NA	NA
4192638:4192655	attL	NA	NA	NA	NA
WP_044800808.1\|4192958_4194311_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	9.0e-95	43.1
WP_016351995.1\|4194647_4196084_-	ammonium transporter	NA	NA	NA	NA
WP_044801234.1\|4196663_4197704_-\|integrase	site-specific integrase	A5X9F3	Aeromonas_virus	2.4e-156	78.5
WP_044800809.1\|4197958_4198741_+	TIGR04255 family protein	NA	NA	NA	NA
WP_144406155.1\|4198752_4199403_+	hypothetical protein	NA	NA	NA	NA
WP_044800810.1\|4199399_4200233_+	hypothetical protein	NA	NA	NA	NA
WP_024943320.1\|4200292_4200967_-	helix-turn-helix domain-containing protein	A0A1I9KG86	Aeromonas_phage	3.4e-42	43.4
WP_044800811.1\|4201100_4201286_+	Cro/Cl family transcriptional regulator	NA	NA	NA	NA
WP_044800812.1\|4201297_4201585_+	hypothetical protein	NA	NA	NA	NA
WP_080891445.1\|4201520_4202096_+	hypothetical protein	A5X9F7	Aeromonas_virus	2.5e-38	55.7
WP_044800813.1\|4202109_4202538_+	hypothetical protein	NA	NA	NA	NA
WP_044800814.1\|4202576_4202762_+	hypothetical protein	NA	NA	NA	NA
WP_044801236.1\|4202785_4203052_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_044800815.1\|4203765_4204050_+	hypothetical protein	NA	NA	NA	NA
WP_080891446.1\|4204049_4206815_+	replication endonuclease	A5X9G4	Aeromonas_virus	1.9e-123	36.7
WP_044800816.1\|4206952_4207333_-	hypothetical protein	NA	NA	NA	NA
WP_144406156.1\|4207640_4208174_+	hypothetical protein	NA	NA	NA	NA
WP_080741289.1\|4208208_4208463_-	ogr/Delta-like zinc finger family protein	A5X9H0	Aeromonas_virus	2.4e-25	66.2
WP_080891447.1\|4208520_4209336_-\|portal	phage portal protein	A5X9H1	Aeromonas_virus	8.0e-115	76.2
WP_080891448.1\|4209253_4211383_-\|terminase	terminase	A5X9H3	Aeromonas_virus	9.1e-243	66.9
WP_080891449.1\|4211560_4212478_+\|capsid	capsid protein	A5X9H4	Aeromonas_virus	1.5e-69	48.3
WP_044800819.1\|4212488_4213568_+\|capsid	phage major capsid protein, P2 family	A5X9H5	Aeromonas_virus	2.5e-140	69.6
WP_044800820.1\|4213570_4214296_+\|terminase	terminase	A5X9H6	Aeromonas_virus	1.0e-97	74.1
WP_044801242.1\|4214401_4214863_+\|head	head completion/stabilization protein	A5X9H7	Aeromonas_virus	7.4e-49	68.0
WP_044800821.1\|4214859_4215375_+	phage protein	A5X9H8	Aeromonas_virus	3.8e-54	57.0
WP_044800822.1\|4215400_4216537_+	DUF2586 family protein	A5X9I0	Aeromonas_virus	1.3e-190	87.8
WP_044800823.1\|4216540_4216996_+	DUF2597 family protein	A5X9I1	Aeromonas_virus	3.4e-70	86.0
WP_042064911.1\|4217006_4217216_+	TraR/DksA family transcriptional regulator	A5X9I2	Aeromonas_virus	1.0e-29	88.4
WP_044800824.1\|4217239_4217551_+\|holin	phage holin, lambda family	A5X9I3	Aeromonas_virus	4.5e-26	56.4
WP_044800825.1\|4217552_4218032_+	TIGR02594 family protein	A0A1I9KGA3	Aeromonas_phage	2.6e-65	70.7
WP_044800826.1\|4218028_4218463_+	hypothetical protein	NA	NA	NA	NA
WP_043122797.1\|4218586_4218853_+	hypothetical protein	A5X9I7	Aeromonas_virus	2.6e-22	63.4
WP_044800828.1\|4219041_4221099_+\|tail	phage tail tape measure protein	A5X9I9	Aeromonas_virus	1.8e-203	59.1
WP_044800829.1\|4221095_4221419_+	DUF2590 family protein	A5X9J0	Aeromonas_virus	7.2e-51	93.5
WP_044800830.1\|4221415_4222603_+	phage protein	A5X9J1	Aeromonas_virus	3.9e-203	90.4
WP_044800831.1\|4222595_4223198_+	phage protein	A5X9J2	Aeromonas_virus	1.7e-106	92.4
WP_044800832.1\|4223194_4225285_+\|tail	phage tail protein	A5X9J3	Aeromonas_virus	1.1e-298	73.7
WP_044800833.1\|4225300_4225726_+\|tail	tail protein	A5X9J5	Aeromonas_virus	8.3e-31	49.6
WP_044800834.1\|4225722_4226604_+	hypothetical protein	A5X9J6	Aeromonas_virus	8.4e-126	79.2
WP_044800835.1\|4226600_4227152_+	hypothetical protein	A5X9J7	Aeromonas_virus	2.1e-66	77.0
WP_044800836.1\|4227148_4228762_+	hypothetical protein	A5X9J8	Aeromonas_virus	6.6e-262	81.9
WP_052508950.1\|4228772_4229471_+	phage virion morphogenesis protein	NA	NA	NA	NA
WP_044800837.1\|4230085_4231456_+	Fic family protein	NA	NA	NA	NA
WP_016352039.1\|4231838_4232360_+	RDD family protein	NA	NA	NA	NA
WP_011707420.1\|4232517_4233588_-	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_005305138.1\|4233729_4234842_-	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_011707422.1\|4235014_4236523_+	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	4.4e-50	37.6
WP_044800838.1\|4236685_4237141_+	DNA polymerase III subunit chi	NA	NA	NA	NA
4236714:4236731	attR	NA	NA	NA	NA
WP_044800839.1\|4237206_4240059_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.4e-137	36.2
WP_029302168.1\|4240245_4241538_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_016352045.1\|4241556_4242222_+	DedA family protein	NA	NA	NA	NA
WP_011707427.1\|4242361_4243189_+	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_005305164.1\|4244426_4244615_-	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	2.9e-12	66.7
WP_011707428.1\|4244708_4245956_-	aspartate kinase	NA	NA	NA	NA
WP_043127213.1\|4245972_4248597_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	6.2e-76	37.9
WP_044800840.1\|4249069_4249570_-	regulatory protein RecX	NA	NA	NA	NA
WP_011707431.1\|4249611_4250676_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	1.5e-116	64.4
WP_044800841.1\|4250755_4251247_-	nicotinamide-nucleotide amidase	B5TK85	Pseudomonas_phage	1.1e-29	51.6
WP_044800842.1\|4251481_4254064_+	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	3.2e-32	23.9
WP_044800843.1\|4254157_4255756_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.4e-25	25.2
WP_011707435.1\|4255765_4256293_-	hypothetical protein	NA	NA	NA	NA
WP_011707436.1\|4256456_4256936_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_044798965.1\|4257031_4257994_+\|transposase	IS1595 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP010947

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection