CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LK936442	Burkholderia pseudomallei strain C1 chromosome 1	2 crisprs	DEDDh,DinG,csa3,cas3,WYL	0	2	8	0
NZ_LK936443	Burkholderia pseudomallei strain C1 chromosome 2	1 crisprs	cas3,DinG,csa3,PD-DExK	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LK936442_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LK936442_1

1122351-1122544

Orphan

Consensus_repeat	Method
CTTCGATGCCTTCGGTGCCTTCGGTGCCTTCG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_LK936442_1

>merge|NZ_LK936442|1|1122351-1122544|CRISPRCasFinder
CTTCGGTGGCTTCGACGGCTTCGGTGGCTTCGATGCCTTCGGCGGCTTCGATGCCTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCGACAATCTCACCGTCTTCGAAGTTTTCGCAGCCTCCGTCGCCTTCCTTTCCTTTG

>NZ_LK936442|1|1|1122351-1122544|CRISPRCasFinder
CTTCGGTGGCTTCGACGGCTTCGGTGGCTTCG	ATGCCTTCGGCGGCTTCGATGC
CTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCG	GTGCCTTCGGTGCCTTCGGTGC
CTTCGGTGCCTTCGGTGCCTTCGGTGCCTTCG	ACAATCTCACCGTCTTCGAAGT
TTTCGCAGCCTCCGTCGCCTTCCTTTCCTTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LK936442.1\|WP_004193161.1\|1130687_1131401_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|185029
NZ_LK936442.1\|WP_004191758.1\|1127902_1128991_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_LK936442.1\|WP_011325270.1\|1133468_1134167_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|380375
NZ_LK936442.1\|WP_004553878.1\|1132297_1133074_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270421
NZ_LK936442.1\|WP_024431985.1\|1119160_1119919_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235975
NZ_LK936442.1\|WP_004554524.1\|1114471_1116451_+\|fused-uroporphyrinogen-III-synthase-HemD/membrane-protein-HemX	unknown	unknown	gnl\|CDD\|235899
NZ_LK936442.1\|WP_004526333.1\|1116455_1117646_+\|heme-biosynthesis-protein-HemY	unknown	unknown	gnl\|CDD\|273126
NZ_LK936442.1\|WP_024431984.1\|1120005_1121445_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143427
NZ_LK936442.1\|WP_004538480.1\|1124045_1125224_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|377314
NZ_LK936442.1\|WP_004193185.1\|1113482_1114472_+\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NZ_LK936442.1\|WP_009929418.1\|1123024_1123414_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197666
NZ_LK936442.1\|WP_004191560.1\|1110175_1113160_-\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|234570
NZ_LK936442.1\|WP_009970280.1\|1109030_1109786_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_LK936442.1\|WP_004522540.1\|1108032_1108848_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375319
NZ_LK936442.1\|WP_004192356.1\|1121605_1122133_+\|inorganic-diphosphatase	unknown	unknown	gnl\|CDD\|179262
NZ_LK936442.1\|WP_038708144.1\|1129885_1130665_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226961
NZ_LK936442.1\|WP_004193987.1\|1127105_1127444_+\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|366157
NZ_LK936442.1\|WP_004522525.1\|1131397_1132087_-\|histidine-ABC-transporter-permease-HisQ	unknown	unknown	gnl\|CDD\|185089
NZ_LK936442.1\|WP_004192161.1\|1117814_1119122_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_LK936442.1\|WP_004526341.1\|1125344_1127045_+\|NAD+-synthase	unknown	unknown	gnl\|CDD\|237577

Protein	Function_ID	Function_description	E-value
NZ_LK936442.1\|WP_004193161.1\|1130687_1131401_-\|ABC-transporter-permease	gnl\|CDD\|185029	PRK15069, PRK15069, histidine ABC transporter permease HisM.	1.45713e-163
NZ_LK936442.1\|WP_004191758.1\|1127902_1128991_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	1.98369e-64
NZ_LK936442.1\|WP_011325270.1\|1133468_1134167_+\|pirin-family-protein	gnl\|CDD\|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	5.01337e-78
NZ_LK936442.1\|WP_004553878.1\|1132297_1133074_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270421	cd13703, PBP2_HisJ_LAO, Substrate binding domain of ABC-type histidine- and lysine/arginine/ornithine transporters; the type 2 periplasmic-binding protein fold. This subgroup includes the periplasmic-binding proteins, HisJ and LAO, that serve as initial receptors in the ABC transport of histidine and lysine-arginine-ornithine amino acids. They are belong to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.1024e-129
NZ_LK936442.1\|WP_024431985.1\|1119160_1119919_-\|SDR-family-oxidoreductase	gnl\|CDD\|235975	PRK07231, FabG-like, SDR family oxidoreductase.	2.07034e-136
NZ_LK936442.1\|WP_004554524.1\|1114471_1116451_+\|fused-uroporphyrinogen-III-synthase-HemD/membrane-protein-HemX	gnl\|CDD\|235899	PRK06975, PRK06975, bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed.	0
NZ_LK936442.1\|WP_004526333.1\|1116455_1117646_+\|heme-biosynthesis-protein-HemY	gnl\|CDD\|273126	TIGR00540, TPR_hemY_coli, heme biosynthesis-associated TPR protein. Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General].	4.7326e-120
NZ_LK936442.1\|WP_024431984.1\|1120005_1121445_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143427	cd07109, ALDH_AAS00426, Uncharacterized Saccharopolyspora spinosa aldehyde dehydrogenase (AAS00426)-like. Uncharacterized aldehyde dehydrogenase of Saccharopolyspora spinosa (AAS00426) and other similar sequences, are present in this CD.	0
NZ_LK936442.1\|WP_004538480.1\|1124045_1125224_-\|N-acetyltransferase	gnl\|CDD\|377314	pfam04339, FemAB_like, Peptidogalycan biosysnthesis/recognition. FemAB_like is a family of both baterial and Viridiplantae proteins with responsibility for building interpeptide bridges in peptidoglycan. Such a function is feasible for bacteria but less likely for the plant members of this family. Perhaps the plant-members are using homologous proteins to recognize bacterial peptidoglcans as part of their innate immune system.	0
NZ_LK936442.1\|WP_004193185.1\|1113482_1114472_+\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	3.39289e-158
NZ_LK936442.1\|WP_009929418.1\|1123024_1123414_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.4642e-07
NZ_LK936442.1\|WP_004191560.1\|1110175_1113160_-\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NZ_LK936442.1\|WP_009970280.1\|1109030_1109786_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.15347e-26
NZ_LK936442.1\|WP_004522540.1\|1108032_1108848_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	6.59944e-35
NZ_LK936442.1\|WP_004192356.1\|1121605_1122133_+\|inorganic-diphosphatase	gnl\|CDD\|179262	PRK01250, PRK01250, inorganic diphosphatase.	2.55902e-115
NZ_LK936442.1\|WP_038708144.1\|1129885_1130665_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226961	COG4598, HisP, ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism].	1.09879e-161
NZ_LK936442.1\|WP_004193987.1\|1127105_1127444_+\|P-II-family-nitrogen-regulator	gnl\|CDD\|366157	pfam00543, P-II, Nitrogen regulatory protein P-II. P-II modulates the activity of glutamine synthetase.	1.39283e-55
NZ_LK936442.1\|WP_004522525.1\|1131397_1132087_-\|histidine-ABC-transporter-permease-HisQ	gnl\|CDD\|185089	PRK15135, PRK15135, histidine ABC transporter permease HisQ.	4.18901e-109
NZ_LK936442.1\|WP_004192161.1\|1117814_1119122_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.9134e-100
NZ_LK936442.1\|WP_004526341.1\|1125344_1127045_+\|NAD+-synthase	gnl\|CDD\|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0

>NZ_LK936442.1|WP_004192356.1|1121605_1122133_+|inorganic-diphosphatase
MSFSNVPAGKDLPQDFNVIIEIPAQSEPVKYEADKELGLLVVDRFIGTGMRYPVNYGFIPQTLSGDGDPVDVLVITPFPLLAGSVVRARALGMLKMTDESGVDAKLVAVPHDKVCPMTANLKSIDDVPAYLKDQIKHFFEQYKALEKGKWVKVEGWDGIDAAHKEITDGVANFKK
>NZ_LK936442.1|WP_024431984.1|1120005_1121445_-|aldehyde-dehydrogenase-family-protein
MEEAKHFIAGAWTAPAGGGTIAVIDPSDGEPFARLARGTAPDVGAAVQAARAAFDGSWGALGAADRGRMLYRLSMLVAACREELALIESRDTGKPLTQARADADALARYLEFYAGAADKLHGETLPYRDGYTVLTLREPHGVTGHIVPWNYPMQILGRSVGAALAAGNACVVKPSEDACLSILRVATLAAEAGLPEGAFNVVTGYGHEAGAALARHPGVDHLSFTGSPDTGRLVAQMAAEHHASVTLELGGKSPQIVFADADLDAALPVLVSAIVQNAGQTCSAGSRVLIDKAVYEPLVERLAAAFNGLKVGPGRADLDCGPLINAKQQQRVWDFLSDAQHDGIAMAAHGQVVPDAPETGFYQAPALLRDVPHTHRLAQEEVFGPVLAAMPFADEDEALALANGTPFGLVAGIWTRDGARQMRLARKVRAGQVFVNNYGAGGGVELPFGGTGRSGYGREKGFEALYGFTVLKTIALRHG
>NZ_LK936442.1|WP_024431985.1|1119160_1119919_-|SDR-family-oxidoreductase
MRLSGKTAVVTGAGSGFGEGIAKTFAREGACVVVNDLHAAAAERVASEIALAGGRALAVAGDVSRGEDWQALRDAALAAFGSVQVVVNNAGTTHRNKPVLDITEAEYDRVYAINMKSLFWSVQTFVPYFRGAGGGAFVNIASTAAVRPRPGLVWYNSTKGAMLTASKTLAAELGADRIRVNCVNPVLGETGLTSEFMGVPDTSENRARFVATIPLGRLSTPQDIANAALYLASDEAAFVTGACLEVDGGRCV
>NZ_LK936442.1|WP_004192161.1|1117814_1119122_-|MFS-transporter
MASTLPATTPGAPSAFEAATYRKVSWRLAPLLLLCYVVAYLDRVNVGFAKLQMAADLHLSDAVYGLGAGIFFIGYFLFEVPSNVILHKVGARVWIARIMVTWGIISALTMFVSTPAMFYTMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTLFMTAVALSGVVGGPISGYILKTFDGMNGWRGWQWLFLLEGVPSVLVGILLLFALDDGIAKAKWLDGDEKALLSRNVAAEEARKEDLPLSAVFASPRVWLMGFIYFSFVMGLYGVGFWLPTIIKSTGVTDAFAIGLLSAVPYAAAVVAMLAVARSADRRRERRWHLAIPAAAGALGLVLSVVWAHDTLLAMLGLTIATMGILTTLPLFWSLPTAFLGGTAAAAGIAIINSVGNLAGFLSPYLVGWLKQASASNAAGMYMLAGFLVLGGLLALTVPKSLVDI
>NZ_LK936442.1|WP_004526333.1|1116455_1117646_+|heme-biosynthesis-protein-HemY
MTLRGIIWLAVLFAIAAALATVGRFDTGQVLIVYPPYRIDVSLNFFVLAIIVAFIVLYALMRIVRNVWRMPQRVAAYRARMRNERAQAALRDALANLYAGRFSRAEKAARDALAVDANQSAASLVAAAATHRMHEYARRDEWLAKVSGQEWQDARLLATADMRADGRDAEGALAALAEMQASGGKRIHAQQIALRAQQQNKNWAEVLKIAKALEKREALHPAAAVRLRQQAAEHLLRDRRHDADALLEVWQSLSAAERQSPRLADLAAELLIALERRQEARRIVEDALAHNWNARLLRRYPDTAGADALPLIQKAEGWRRERPDDADLLFALGRLCQQQQLWGKAQSFLESALKLADDEPLRIRAHRALARLFEHLGETDKAAQHYRESALAITVV
>NZ_LK936442.1|WP_004554524.1|1114471_1116451_+|fused-uroporphyrinogen-III-synthase-HemD/membrane-protein-HemX
MAGAPRTFTAVLTRPDGQSAALAAQLAAAGIDVLDFPLIDIAPLADDAPLAEAFARLDAYALVVFVSPNAVDHALARLGAIWPHPLPIGVVGPGSVAALARHGIAAPAHRVIAPSAPDDGGEPHYDSESLFAEIARAFNGEAKLAGKRVLIVRGDGGREWLAERLREAGAEVELVAAYRRVSPEPSIGAWERVHALLSGAPHAWLVTSSEGVRNLQELAHEHLNETEIDALKHARFVAPHSRIVETARALGFDRITLTGAGDERIVRAFRTLADQADQPATAAPMPSRMTDTNDTKDVSSKPAAAPVAPPNQPFTPFETKERRGAASAALWFLVVVIAAAAGVGGYALNRKVDRLDQHATERQKALDAQTAELRTKTEQALASVRQADSQLSQLEGKLADAQTAQTALQQQYQDLSRNRDAWMIEEVGQMLSSASQQLLLTGNTQLALIALQNADARLASSQSAQAVVVRKAIAQDIERLKAAPSADLTGLAIKLDDAIAKVDTLPLAGEVLAPHAQAKPDAAASARQAAAAAGEPRWKAWWRGFSAGIGEQLKSLVEVRRIDHADAMLASPEQGYFVRENVKLRLLSARLSLLARDDGAMKSDLHAAQAAVARYFDGASKDTRVVQDLLKQVDAASLTVAVPNLNTSLNAVQQFKSRG
>NZ_LK936442.1|WP_004193185.1|1113482_1114472_+|hydroxymethylbilane-synthase
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAERAVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRRVSDALERQGARAIVDALVAASAQAQKGGA
>NZ_LK936442.1|WP_004191560.1|1110175_1113160_-|phosphoenolpyruvate-carboxylase
MKSSGSARATRRNAVSSSSAPAHAEPPARRAAKPARKLDGAAARPLAPTNAASAKPQGRTREDKDRPLFEDIRYLGRLLGDVVREQEGDAVFDVVETIRQTAVKFRREDDKAAAQTLEKMLRKLTPEQTVSVVRAFSYFSHLANIAEDRHHNRRRRIHALAGSAAQAGTVAYALDKLKQAGDASSKTIKQFFEGALIVPVLTAHPTEVQRKSILDAQHDIARLLAERDQPLTARELAHNEALLRARVTTLWQTRMLRDARLTVADEIENALSYYRATFLDELPALYADIEEALAEHGLRARVPAFFQMGSWIGGDRDGNPNVTAATLDEAISRQAAVIFEHYLEQVHKLGAELSVSNLLVGASDALKALAAASPDQSPHRVDEPYRRALIGVYTRLAASARVRLGEGTVPVRSAGRGAAPVRATPYADAEEFAADLRVLTDSLALHHGESLATPRLAPLMRAAEVFGFHLASIDLRQSSDIHEAVVAELLARGGVEADYAALPEADKLRVLLAALADPRPLRSPYLDYSDLAKSELGVLERAHAIRAQFGARAVRNYIISHTETVSDLVEVLLLQKETGLFEGTLGTPHANARNGLMVIPLFETIADLRNASDIMRAFFALPGVGELLAHQGHEQEVMLGYSDSNKDGGFLTSNWELYRAELALVDLFDERGIKLRLFHGRGGTVGRGGGPTYQAILSQPPGTVNGQIRLTEQGEVIASKFANPEIGRRNLETVVAATLEATLAPHSNAPKQLPAFEAAMQTLSDAAMASYRALVYETPGFTDYFFSSTPITEIAELNIGSRPASRKLQDPKNRKIEDLRAIPWGFSWGQCRLLLTGWYGFGSAVAAYLDGAPDAAERGKRVALLKKMNKTWPFFANLLSNMDMVLAKTDLAVASRYAQLVADKKLRKHVFERIVAEWHRTADALAEITGAHARLAANPLLARSIKNRFPYLDPLNHLQVELIKRHRAGDTNARLRRGIHLTINGIAAGLRNTG
>NZ_LK936442.1|WP_009970280.1|1109030_1109786_+|class-I-SAM-dependent-methyltransferase
MKHHDRVADAFGTTASAYLTSAVHATGADLDTFAAEIGATPGARVLDLGCGAGHASFAAARGGAHEVIAYDLAPQMLATVEAAARERGLSNVRIEQGAAERLPFADASFDWIVSRMSAHHWHGVPRALAEARRVLKPGGRVLFVDVASADHPLADTHLQAVEVLRDASHVRDYRVDEWLAFFAQAGFAARVRERWRLSIGFDGWVARMRTPDVRAHAIRALWADAPDEVRAYFDVQPDGSFKLDVVMIDAR
>NZ_LK936442.1|WP_004522540.1|1108032_1108848_-|helix-turn-helix-domain-containing-protein
MSRQPVPPPSLDATPARALGEFIRAHRERLSPQAVGLPPGPRRRTPGLRREEVAQLCGVSPTWYTWIEQGREVSASADALARIAVALRLSRAERAYLFELAAQRDPAEPEFAASDVPDTLVAAVQLIATPAYVLDRQWNALAWNDAAAALFIGWLDGERDERNLLRFTFASPAARALIVDWETRARRLVAEFRADTIRHLNDAPTRALIDSLLAESDAFAHYWASQDVGEREGGERAFDHPREGRVVYQQMTLKPAHREDLKLVVLVREAA
>NZ_LK936442.1|WP_009929418.1|1123024_1123414_-|helix-turn-helix-domain-containing-protein
MRQVRRLPRERDRQLAGRVRVAGERFAISRGTLRRRLHHEALTFHALLARARIGEAERRRRHTRLPIGAIGARAGFGSASAFSRFFTRARRGVEPLSRRARRQMALSRTISATLAASRHAALSCPGICI
>NZ_LK936442.1|WP_004538480.1|1124045_1125224_-|N-acetyltransferase
MKHERRDYRMGILTSVLDASAAEWDALVARAPRPTPFLKHAFLSALHRAGCATDGTGWTPRFVTLADSATDALVAAAPVYAKRHSYGEYVFDWAWADAYQRNGLPYYPKLLCAVPFTPVQGSRLLAVDDDARRRLAATLVALAEQSDVSSLHVLFPTGDEARALADMGMMLREGVQFHWLNDGYRDFDAFLGTLEQKKRKNIRAERRKVADAGVTLRRVRGEDATDADWRFFARCYRQTYREHFSSPYLNLEFFREIGATMPENLLLVIAERDGRPIASALAVYQRGEAGGGTLYGRYWGALEHVPCLHFETAYYQLLEFCIEERLDTFEGGAQGEHKLARGFMPTVTHSAHWLAHPAFADAVGHFLAQETNQIHAYVDELREHNPFRAGER
>NZ_LK936442.1|WP_004526341.1|1125344_1127045_+|NAD+-synthase
MKTRIALAQLNVTVGDFAGNVAKIVAAAQAAHDAGAHLLIAPELALSGYPPEDLLLRPAFYAASDAALAALAAQLKPLAGLAVLVGHPLRAAGAGASSADGNANRPIERGAAPVDTYNAASLIVGGEVVGTYRKQDLPNTEVFDEKRYFATDAAPYVFELNGVRFGVVICEDVWHASAAQLAKAAGAQVLIVPNGSPYHMHKEAVRIDILRARIRETGLPMVYVNLVGGQDELVFDGGSFVLDGAGELVAKMPQFEEGHAIVEFDGARALPAPIAPALPVEAQVYRALVLGVRDYIGKNGFPGAIVGLSGGVDSALVLAVAVDALGAERVRAVMMPSRYTADISTTDAADMAKRVGVRYDEIAIAPMFDAFRASLAAEFAGLAEDATEENIQARIRGTLLMALSNKFGSIVLTTGNKSEMAVGYCTLYGDMAGGFAVIKDIAKTLVYRLCRYRNAAAEYGALDVIPERILTRAPSAELRENQTDQDSLPPYDVLDAIMRMYMEEDRPLAEIVAAGYAEADVKRVTRLIKINEYKRRQAPVGIRVTHRAFGRDWRYPITSRFIESID
>NZ_LK936442.1|WP_004193987.1|1127105_1127444_+|P-II-family-nitrogen-regulator
MKRITAIIKPFKLDEVREALAEVGLTGLTVTEVKGFGRQKGHTELYRGAEYVVDFLPKMKIEVVVANNLVDQVIDAVIGAARTGKIGDGKIFVSDVERVIRIRTGEENEAAV
>NZ_LK936442.1|WP_004191758.1|1127902_1128991_-|porin
MKKVMLAAVLATAGVAAHAQSSVTLYGRLDAGIEYMNGLPSANGGSTSRWRAESGNWGTSLWGLKGSEDIGGGNKIVFQLEGSFDTMNGNGPGAGSIWNRWATIGISNDTYGTLLLGRELAIANGVWDFDPFGQSSWSTASLVRGRNWNKTSNNISYQSPKFYGFDVYGQYALSNATNWNGNGSTSQGRSAGLQLTYTTSLFQIRGLYDEARDPANGKLDDVFNYSREYFAGVNVFLGQFKLQAAYQASHADGGPVVNNGITTTQQVWGGVTWQATPAAALIAAVYHVNANHGGGNANIFTVGGSYNLSKRTLLDVQVATVRNSKTANFGLNANPAGTDISTGNPKFGGSQTGVYAGIQHLF
>NZ_LK936442.1|WP_038708144.1|1129885_1130665_-|ABC-transporter-ATP-binding-protein
MNTQMHKLFVDDLHKRYGNNEVLKGVSLRANAGDVISVIGSSGSGKSTMLRCINFLEQPNAGRIFVDGEEVRTAQDRTGALKAADSKQLRRVRTKLAMVFQHFNLWAHMNVLENVMEAPVHVLGITKREAQERAREYLEKVGLAPRVETQYPSHLSGGQQQRVAIARALAMHPDVMLFDEPTSALDPELVGEVLKVMQKLAEEGRTMIVVTHEMGFARNVSNHVMFLHQGRVEEEGAPADVFGATKSERLKQFLSGSLK
>NZ_LK936442.1|WP_004193161.1|1130687_1131401_-|ABC-transporter-permease
MIELIQEYWRNYLYTDGYRFTGLAITMWLLVVSIGIGFCLSVPLAVARVSKKKWLAGAVWLYTYVFRGTPLYVQLLLCYTGLYSLQAVRGTPMLDAFFRDGMNCTLLAFTLNTCAYTTEIFAGAIKATSYGEIEAARAYGMSTFTLYRRIVLPSALRRALPLYSNEVILMLHATTVAFTATVPDILKIARDVNSATYMSFHAFGIAALLYLAISFTLVWLFRRAERRWLAYLRPQGK
>NZ_LK936442.1|WP_004522525.1|1131397_1132087_-|histidine-ABC-transporter-permease-HisQ
MFLQGYGPLILSGTWQTVKLAVLSLALSFLLGLVGAAAKLSRNRVSNGIGTLYTTLIRGVPDLVLMLLLFYSLQIWLNQLTDLMNWDQIDIDPFAAGVLVLGFIYGAYFTETFRGAFLSVPRGQLEAGSAYGMTNWQVFARVMFPQMMRFALPGIGNNWQVLVKSTALVSIIGLADVVKASQDAGKGTLRFFFFTLLAGAIYLAITTISNFVLMWLEKRYSTGVRKADL
>NZ_LK936442.1|WP_004553878.1|1132297_1133074_-|ABC-transporter-substrate-binding-protein
MKKLALCAALALAAGGAFAKEWKTVRIGVDASYPPFESTAPSGEIVGFDVDLAKEVCKRINAKCTWTPQDLDGIIPALKAKKFDVIVSSLTVTDKRREQIDFSDKLYDAPARMIAKAGSPLAPSVESLKGKRVGVEQGSTQETFAKAHWEPKGVTIVSYQNQDQVYADLGSGRLDATLQDELQADYGFLRTPRGKGFAWAGPAVKDPRTLGDGTAMGLRKEDADLKEAINRALASMHKDGTYDRLSRKYFPYSVYSAK
>NZ_LK936442.1|WP_011325270.1|1133468_1134167_+|pirin-family-protein
MFEIRRAGDRGHADHGWLDTHHSFSFADYRDPEHMYFGALRVLNDDRIAPTRGFGMHPHRDMEIVTYVLEGALAHRDSMGNGSIVRAGDVQRMSAGTGIVHSEYNASCDAPLHLLQIWLLPVEPGGRPGYQEARFTDADKRGRLRLVASPDGRDGAVTVRADASIYAGLVDGDERAEFAPPAGRRAYVHVARGCVVVNGEVLAAGDGARIAEVGRVVFERGERAEVLLFDLA

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Crispr_ID: NZ_LK936442_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LK936442_2

1446256-1446397

Orphan

Consensus_repeat	Method
CGCGTATGCGGCGAACGCCGGCGCGACAAGCGTTGCAGCGCGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LK936442_2

>merge|NZ_LK936442|2|1446256-1446397|CRISPRCasFinder
CGCGTATGCGGCGAACGCCGGCGCGACAAGCGTTGCAGCGCGGCGGACGAATGCCGTTCGCAAGTTCGCAGCGGTTCGCGCTGGAACGGCGTCTGCCGCGTATGCGGCGAACGCCGGCGCGACAAGCGTTGCAGCGCTGGCG

>NZ_LK936442|2|2|1446256-1446397|CRISPRCasFinder
CGCGTATGCGGCGAACGCCGGCGCGACAAGCGTTGCAGCGCGGCGG	ACGAATGCCGTTCGCAAGTTCGCAGCGGTTCGCGCTGGAACGGCGTCTGC
CGCGTATGCGGCGAACGCCGGCGCGACAAGCGTTGCAGCGCTGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LK936442.1\|WP_004193128.1\|1448277_1448490_-\|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl\|CDD\|182532
NZ_LK936442.1\|WP_009929716.1\|1444372_1445656_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_LK936442.1\|WP_004192284.1\|1455022_1455958_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|183067
NZ_LK936442.1\|WP_160974052.1\|1454806_1455019_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LK936442.1\|WP_045140991.1\|1452565_1453762_+\|cytochrome-b/b6-domain-containing-protein	unknown	unknown	gnl\|CDD\|226602
NZ_LK936442.1\|WP_004191983.1\|1447801_1448026_-\|lipoprotein	unknown	unknown	unknown
NZ_LK936442.1\|WP_004192878.1\|1430594_1430786_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LK936442.1\|WP_045140990.1\|1440861_1443534_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|236783
NZ_LK936442.1\|WP_045140988.1\|1433711_1437056_+\|exodeoxyribonuclease-V-subunit-gamma	unknown	unknown	gnl\|CDD\|335690
NZ_LK936442.1\|WP_004545149.1\|1446619_1447552_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|307170
NZ_LK936442.1\|WP_162187254.1\|1433115_1433703_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237171
NZ_LK936442.1\|WP_004193488.1\|1443530_1443935_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
NZ_LK936442.1\|WP_004526525.1\|1453777_1454569_+\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239026
NZ_LK936442.1\|WP_004521865.1\|1448713_1450645_-\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NZ_LK936442.1\|WP_004521871.1\|1430782_1433059_-\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|372320
NZ_LK936442.1\|WP_004526507.1\|1429233_1430598_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182566
NZ_LK936442.1\|WP_004193339.1\|1451284_1451590_+\|pentapeptide-MXKDX-repeat-protein	unknown	unknown	gnl\|CDD\|131998
NZ_LK936442.1\|WP_045140989.1\|1437052_1440865_+\|exodeoxyribonuclease-V-subunit-beta	unknown	unknown	gnl\|CDD\|236784
NZ_LK936442.1\|WP_004535481.1\|1451750_1452575_+\|DUF1223-domain-containing-protein	unknown	unknown	gnl\|CDD\|369071
NZ_LK936442.1\|WP_004193167.1\|1428912_1429092_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_LK936442.1\|WP_009929716.1\|1444372_1445656_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	7.96069e-53
NZ_LK936442.1\|WP_004192284.1\|1455022_1455958_+\|EamA-family-transporter	gnl\|CDD\|183067	PRK11272, PRK11272, putative DMT superfamily transporter inner membrane protein; Provisional.	4.46808e-57
NZ_LK936442.1\|WP_045140991.1\|1452565_1453762_+\|cytochrome-b/b6-domain-containing-protein	gnl\|CDD\|226602	COG4117, COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion].	1.11017e-55
NZ_LK936442.1\|WP_004526525.1\|1453777_1454569_+\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239026	cd02108, bact_SO_family_Moco, bacterial subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. This domain is found in a variety of oxidoreductases. Common features of all known members of this family, like sulfite oxidase and nitrite reductase, are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	1.21624e-90
NZ_LK936442.1\|WP_045140990.1\|1440861_1443534_+\|AAA-family-ATPase	gnl\|CDD\|236783	PRK10875, recD, exodeoxyribonuclease V subunit alpha.	1.4465e-72
NZ_LK936442.1\|WP_045140988.1\|1433711_1437056_+\|exodeoxyribonuclease-V-subunit-gamma	gnl\|CDD\|335690	pfam04257, Exonuc_V_gamma, Exodeoxyribonuclease V, gamma subunit. The Exodeoxyribonuclease V enzyme is a multi-subunit enzyme comprised of the proteins RecB, RecC (this family) and RecD. This enzyme plays an important role in homologous genetic recombination, repair of double strand DNA breaks resistance to UV irradiation and chemical DNA-damage. The enzyme (EC:3.1.11.5) catalyzes ssDNA or dsDNA-dependent ATP hydrolysis, hydrolysis of ssDNA or dsDNA and unwinding of dsDNA. This family consists of two AAA domains.	0
NZ_LK936442.1\|WP_004193128.1\|1448277_1448490_-\|glycine-zipper-2TM-domain-containing-protein	gnl\|CDD\|182532	PRK10540, PRK10540, osmotically-inducible lipoprotein OsmB.	5.81885e-06
NZ_LK936442.1\|WP_004545149.1\|1446619_1447552_-\|DMT-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	4.58404e-12
NZ_LK936442.1\|WP_004193488.1\|1443530_1443935_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	3.43394e-65
NZ_LK936442.1\|WP_162187254.1\|1433115_1433703_-\|hypothetical-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	6.86199e-06
NZ_LK936442.1\|WP_004521865.1\|1448713_1450645_-\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NZ_LK936442.1\|WP_004521871.1\|1430782_1433059_-\|FUSC-family-protein	gnl\|CDD\|372320	pfam12805, FUSC-like, FUSC-like inner membrane protein yccS. This family has similarities to the fusaric acid resistance protein family. The proteins are lodged in the inner membrane.	6.66104e-82
NZ_LK936442.1\|WP_004526507.1\|1429233_1430598_-\|amino-acid-permease	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
NZ_LK936442.1\|WP_004193339.1\|1451284_1451590_+\|pentapeptide-MXKDX-repeat-protein	gnl\|CDD\|131998	TIGR02953, conserved_hypothetical_protein, pentapeptide MXKDX repeat protein. Members of this protein family are small bacterial proteins, each with an N-terminal signal sequence followed by up to 11 imperfect repeats of a pentapeptide. The pentapeptide repeat usually follows the form Met-Xaa-Lys-Asp-Xaa.	0.000353246
NZ_LK936442.1\|WP_045140989.1\|1437052_1440865_+\|exodeoxyribonuclease-V-subunit-beta	gnl\|CDD\|236784	PRK10876, recB, exonuclease V subunit beta; Provisional.	0
NZ_LK936442.1\|WP_004535481.1\|1451750_1452575_+\|DUF1223-domain-containing-protein	gnl\|CDD\|369071	pfam06764, DUF1223, Protein of unknown function (DUF1223). This family consists of several hypothetical proteins of around 250 residues in length which are found in both plants and bacteria. The function of this family is unknown. Structurally it lies in the Thioredoxin-like superfamily.	4.25655e-68

>NZ_LK936442.1|WP_009929716.1|1444372_1445656_-|EAL-domain-containing-protein
MPKTQGFSPESLISQFTRCDAGWCVRYHDVTLASAFQPVISITHKRVVGYEALARATDANGAPISPDTLFARAQARGETILLDRLTRCLHVANFAAQDTGACWLFLNVLPQMFDAGIAPGAFIEALCAHFALPPTRVVLEVIEQPSRNEVALARTIDMIQHGDFLIAVDDFGTGFSNFDRIWQIKPDIVKLDRSILERSLAASDAHRIIHHLVTMLHHAGTMVLAEGVENEDALQILMDADVDFVQGFCFGRPASSLEHARRAAPARIEAAWRRFAERTKARCGDVVHPGFDTIERIMLTGAADYAQTRNLRDAAQRLLTSPIVRRVFVAEANGEQVEPSVAIETPEAPSATARRLAPLLPELHCNWSRRAYFQRAIAAPGRVALMGPHFSLTDGRDCYTAAVAIHLGTTLKVFCVDFDFSSYGDGR
>NZ_LK936442.1|WP_004193488.1|1443530_1443935_+|aminoacyl-tRNA-hydrolase
MTLRYAFSPDEVELTAVRAQGAGGQNVNKVSSAIHLRFDIRASSLPDDVKARLFARADQRITREGVIVIKAQEYRTQEKNRAAALARLDTLIRSAGVTPRKRVATRPTRASKERRLAEKGRRSEVKSGRGRVVE
>NZ_LK936442.1|WP_045140990.1|1440861_1443534_+|AAA-family-ATPase
MSVVDERFAWTGGLADRLPEPADFGLALAEGFARRIGMLSRRVGASAAAARWAARAAFAASRATAAGHVCVALRALAQRYDEPYDDVRAALAASGVTAFDGIVRGGECPLVVDRDGRLYLARYFEYETRLANALVERSRCGGAPAGGADALSPDALGERLVRYFGPQKERGVDWQRVAALIALTGRVTIVSGGPGTGKTTTVVGVIACLLDAHPDLRIALAAPTGKAAQRMQEALHARAGSLPAELAARLPRTSCTLHRLLGGGPGGRFAHHRDNPLPYDLVVVDEASMIDVALAAHLLAALAPNARLVLLGDKDQLAAVEAGAVFAELSARPAFSPATCATIARALGVGEAEFVAALPDGFVVQAAGAERVADARAAAADMDAAARGTAGAAAAAARATAAAAARMTTAAAAARGAAPAPHAGRRGGGRASNRTVDDAQGSLFAFDDDAFGVGTSGGEPGAGAQGAGRRDGGAPSLDGPHAGHRDGGASPGVAHSRRDAFDARARSGPADVSDLENAARAYAPAGAAGPADSPADASFVEPAAWIEADELAWLDNAVFSFSEGASANAEADGRRSAAATATDADARTAPPVAREATAPTPRETARSDGSAVAPLTDCVVWLERNYRFGLDSPIGRLSLAIRRGAVQDALDALSTQDDAAARFSDDGGATLSAATVEQLARGFAGYAAALRDALATPEPDALPLFDVLNRFRVLCATRTGARGAEEVNARMAAEVRRAVRVPLALGAHWFAGRPVMVTRNDYALGLFNGDIGIALPGARGALRVWFRGADGRARAVSPAALPPHDTAFALTVHKSQGSEFDDAALILPASFNRVLSRELVYTAITRARARVQVIGSRAVLALAIATRTARDSGLAARIADALRARQEGAR
>NZ_LK936442.1|WP_045140989.1|1437052_1440865_+|exodeoxyribonuclease-V-subunit-beta
MSHVAPSGPSASELDVFACPLDGVNQIEASAGTGKTWNICALYVRLLLEKDLGADEILVVTFTKAATAELHERIRARLAQLAHALDTGDDGSDPFIARLFETTLAPERGLDPQTAAKRVRRALRAFDQAAIHTIHAFCQRALQEAPFAAAMPFAFEMEADDGALRFELAADFWRTRVEPVAAAYPAFAEWLVEYGAGPAALDAQLARRLKKPLARLRWDGLHAADDGAESAARAHFDTAAAIWRDERGVLGTLLADAQPSLNQRSHKPEAVSEALDAWARYFEQASAVAALPRAALKLTQSALEKATKKGGATPRHAFFDVAQALEAAVAALEAAQRARWLSLVEQWLDAAPAELAQRKRTRRVVSFDDLLANLYRALDAHPWLRETLRARYPAALIDEFQDTDPLQFAIFDTIFAPAGPLFLVGDPKQAIYSFRAADLHTYLAARARASARYTLAVNQRSTPAIVDACNRVFGANPRAFVLDGLDYEPVRAGSRGRAPLVDATDPLAGAGDFRIWTLPAGDDVLTKRDAQRHAAHACAAEIARLMRGARERAVTLGGEPLAASGIAVLVQTHRQGSLVKRVLAAWGIGSVELAQASVFATIDAEQLERVLAAIDAPGDLRRLRSALASDWFGLDAAALWRLEQGDAEQDGIDAAARGASGNGGGARAASAGAPAPSPADADAMGWVERFSRYRLLWRERGFAVMWRTLAGELRIAERLMAGADGERRVTDVNHLAELTQARASAQPGIAPTLRWLAAQRLEGGGDDAQLRLESDRNLVQIVTVHKSKGLEYAIVFCPFLNDGGLREPAGSGLPDAREYHDESGCAVLHYGCDDEAAERASREAVREQAAERARLVYVALTRAVYRCYLVAGTYQSSRSTKEARRSVLNWLVAGAGRDFDAWLKEPPEDAELAERWQALAGGPVTLGALPVPAHREPLAAGHDAQAMRAARRATRGLRDAWRIASFSSLASAIARDESGIARAADDEMRPDHDALAAALGADALEPPDAAAAIAPAPAAAPRELAEDDILAFPRGAAAGECLHRLLELSNFADASTWPPAALRALHERPVEAELALAERLPAMMTRLVADLAATELVPGMRLAALDPARRLTEMEFLFPAPALDFNALRRLLAAHGYPDVALEAGTLAGFVKGFIDMIVEHDGRFWIVDWKSNHLGTTPEAYGERALDAAMAHHAYHLQALLYMVALHRYLRVRMRGYDYDAHIAGYLYVFVRGVRPDWRNGGASAGVHARRPARALIEALDALMREGDA
>NZ_LK936442.1|WP_045140988.1|1433711_1437056_+|exodeoxyribonuclease-V-subunit-gamma
MLHLFYSNRHETLADALLDDLAFASDGAGPWAAQQVIVPSAALRRRLELDLAKRHGVCANVRFSYLAQWLWAQIGEVLTVPAHSPFAPDRLVWRCYRLLSDHGAAPWRASPRLAAYLAAADAPMRHELAHRIATVFDHYLTYRPEWLAQWQDGESIFALEGAPRHGGEAARDDEAWQAALWRALLAELSDSGMPPAHRFLREARAFDPDVIARARVKWPDAVSVFALPTMPPLHIALLRELSRWIDVRIYALNPCREFWFDIVTAARAESLDAADRLDYQEVGHPLLAEWGRQTQAQLHMLHELTESAAASDASRYADNPAPTWLARVQNAILDLQPEAALGEPPAERGVEVHVCHSLARQLEVLHDRLLAWFDADPSLAPSDVLVAMPDLATAGPLIDAVFGTPAGADAARIPYRITGLPPSQANPVARVLLDWLALPERDVGAPELVEWLRADAVAARYGIDATALETVQTWLAASGARRGLAPDAAEPPNPAVPAPRHTFADALTRLFLGYAMPDGAAPVSTWLPIAGAEGGEAELLGRLARFTDDLDGFARRIARDLTPQGWGDVFADALARFFDSGPAFADALSGVRDALDAMLAAMAEGAAGAALPAAVVRAGLAAALDDPARGGVPWGGVTFSSLTSLRGLPYRIVCLIGMDDGVLPSLVRADEFDLMAVFAKLGDRQRRDDERNLFLDLLLAARERLLIAYTGRSIRDNAPLPPAALVDELLDHLAAASAGPDAPPDAVDAARRAFVIEHPLQPFSAEYFAPGGALFTYDASRATLARLLAEGARAQARPFFAAPLPAEPEQPVAFADFERFWRHPARSLLRARLGIVLLDAQAELVDTEPFELDYAGSDALAERVLPLLIETADAAAFEHALRVADASPEVPGGATGAVRRDHALDALAQLAGNVRRALADGATRVPFAFDVAPAWPAASDARWFGEHDAALAAAATREPLRLHGALARLTAAGQVIYRYARPGARDYLAAWLAHLVYCAIDPGGPRRTLWFGSGDTFEFAPVAAPLEQLAPLAALFRAGRRMPLAFFPRSAWALVSESESKAAGVWINDRVAGEADDASLALAWRGANPSLDEPFGALAHLVFDPLVEHLRRAS
>NZ_LK936442.1|WP_162187254.1|1433115_1433703_-|hypothetical-protein
MKDAGGARPVEKPRIAKGDGRENLADRPGARAPRSRGHRRDSRLVAAAGPRATGRARRRQRLPQPLARAASANGRIASFGSLRERHHAPQSRGPLAALNRRRARRSESERRTPNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPNAERRTPAPKHGFRDAEIR
>NZ_LK936442.1|WP_004521871.1|1430782_1433059_-|FUSC-family-protein
MRYSVEIRKFFYSQYFFGGLRIALGVSLPAVLSLAVLHDRELGFTIATGALGACVVDMPGPLKYKHNEMLACSVIGFFSALATGLATPNIFALWLTIVPLTFVLSLIVVYGNRWPQISFATLFMMVMTLEEKFTPLQALVNASWILAGGLWYTYWATIVSRWQARRIEQQALAESLFACASYLLARADFYDLDADLDECYRNLVARQITAVETQETARDIVLRNLPKLRRGKLDPGRTMMFNLFINSVDLHEMFVGAHTDYPLVRSTFGGSDLMIFYRDLIRKAAADLEEIGFAVLENRLPHSRISVKAELRAIEYEIELMRKKQFAATHPEAYAAVLATFRRIWSATRLIDKMRRNLSGSADAQRTELKIDKALTRFLQKRRMSPLLIFSNLNMGSPSLRHALRVTIAVAVGFWLGRLLPLTNAYWIVMTSIIILKPGYSLTKQRNAQRIVGTLIGCAASLALIYTVHEPHVLIAIMFGSMVMSYSLLLFNYAASVVFTSSYVLLLFHLLAPGNMRIIGERAIDTVVGCMIAIAASRLFPYWEYRAIGKLVADALATTRKYFEATWRAGRGKAAPAVPAADGAAAVPAVAAVVDAVAPGLDGDYQYRLARKNVHIAFANLGQAFQRMMLEPKAHQKFVPELNDLLVQTHVLGAQITAAAPLLRHACEQGNPPALERGMAAVREHLEQAEAGVPPPANQAETSKQLTRELDSMVVDAERSDAGADLTHDLKVLAHQCKQMLASSLLIRKDASVIRLPE
>NZ_LK936442.1|WP_004192878.1|1430594_1430786_-|hypothetical-protein
MSRPPPPFLSTVSRRARTQGFPDYCPRASIGMIYPAPSCLYNFSSASAGPHRPADDTNHSETR
>NZ_LK936442.1|WP_004526507.1|1429233_1430598_-|amino-acid-permease
MKNLQRHLSARHIRFLALGSAIGTGLFYGSASAIRLAGPAVILAYIVGGAAVYMVMRALGEMAVREPVPGSFGHYATENLGPFAGFVTGWTYTLEMVIVAIADITAFGIYMGFWFPHVPQWIWVLAIVAIICGLNLCHVKVFGELEFWLSIVKVGAIVAMIGGGAAILFTGMRLGSGGAPSLANLWSHGGFLPNGVGGLVASLSVVIFAYGGIEVIGMSAGEAKEPERAIPRAINAVPMRILLFYVLTMIVLMSIFPWTGVGANGSPFVQIFSALGVRSAAEILNLVVISAAISAINSDIFGAGRMMYAMALQGQAPRALAAMSARGVPWVTVLVMAGALLVGVVLNYLMPKDVFLMVAASATFATVWVWLMILLSQVAMRRRLGAAEVAALKFKVPFWPVGPALTIAFMAFVIAMLGYFDDTRVALFVGAAWLAILALVFYTRIRPRLAAVAR
>NZ_LK936442.1|WP_004193167.1|1428912_1429092_+|hypothetical-protein
MNDPRSKKNPVFGVAILIVVVIALVIGTILYNAISQKHEYDEAHPHAASAASAASAQHG
>NZ_LK936442.1|WP_004545149.1|1446619_1447552_-|DMT-family-transporter
MNLKNALLLIVLAALWGASFLFIRVGVAEFGVAPLMALRVGIGALFLVALMLTRYAPRELIALLRQHARPLFVVGLLNSAAPFCLFAFAELTLSAGVTSVINATTPLWGALVAYLWLKDSLSLPRALGLVIGFAGVLTLVWDQVFSPHGANPASPATAALAAAAALGATLLYGIAANFTKRKLTGVDPLVSATGSMVGATILLLPFALATWPAAPVSAHAWGSVLALGIACTGVAYFIFFHLIAHIGPARAITVTFVIPVFGILWGALFLGERVSFAMLEGCVIVLLGTALATGAIRRIPGVRPQRNEAA
>NZ_LK936442.1|WP_004191983.1|1447801_1448026_-|lipoprotein
MNKTLVAAALASVALAGCYYPYGYYPASGYYAAPVQTAPVYVAPAYPAYYYPAPSLSLNFGYWSGGGRGYWRHH
>NZ_LK936442.1|WP_004193128.1|1448277_1448490_-|glycine-zipper-2TM-domain-containing-protein
MKSIRRIGVCAMLIATMASLSACDTMTTRQRNAAIGAGIGGVAGAAIGGNALSTIGGAAAGGLVGSQVGK
>NZ_LK936442.1|WP_004521865.1|1448713_1450645_-|phosphomethylpyrimidine-synthase-ThiC
MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLAGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ
>NZ_LK936442.1|WP_004193339.1|1451284_1451590_+|pentapeptide-MXKDX-repeat-protein
MKRNLIAFACVAGFALAAPFAHAQNDAMSKDGMGMSKDAMSKGAMSGDAMSKDAMSKDAMSKDRMGKRHDHMAKGGMKAGPMSKDAMKEPMSSDKMSPMSN
>NZ_LK936442.1|WP_004535481.1|1451750_1452575_+|DUF1223-domain-containing-protein
MSTDMSISFSVSLRAVAAALSLAAAGAAQAAADGACMARSPDGRQALVELYTSEGCSSCPPADDWLARLAARRAALRVVPLALHVDYWDGLGWADRFAQHRFTERQHALAARGGGRFVYTPEVAVDGRELRDWRDADAFGRRVVATAAEPARVGIALAAKRRAGALDVALSVTPRVGAPRALDAYLALYENGVESQVSAGENRGATLRHERVVRQWIGPLAATADAHASLDVRRALPLPANLRAADAARYGVAAFVEDPATGDVLQALDLPLCG
>NZ_LK936442.1|WP_045140991.1|1452565_1453762_+|cytochrome-b/b6-domain-containing-protein
MRLNDARAIDQRTRVSPMSATPTTSASTTAMAGARASGAADAPARAPTGADVDAGATAWADATANATANATTDPTIDATADATTDAMANVTTDAATRVTANPPIHETANVPASTAAAATTEAVAGARAGAALDAAHPGATQTMSQTMSQTMAQTMAQTMAQTMAQTMTQTMTQTMTQAGTEAASPAGTDAAASGTCITRATRARRPIHPLWVRASHWLNALAAVTMALSGWRIYNASPIYAGFVFPRGATLGGWLGGALQWHFAAMWLLFFNGVFYLTMGVATRRFTRKLLPLSASGVARDLRDALRGRLSHDDLSVYNALQRAAYVAAIADLALLVLSGLVIWKSVQFPLLREWLGGYDRARVVHFWAMAFLVAFFVVHVAMAALVPRSLLAMLRGH
>NZ_LK936442.1|WP_004526525.1|1453777_1454569_+|molybdopterin-dependent-oxidoreductase
MSENDRKKRENDIARIDRASLLIDVRKSLALPSRRLFGKRMLTLGGLAMLTGCTLRDDASVDDFLEKVSRANDRVQAWLFGPTRLAPTYAEADITRPFPFNAFYGIDEVPRVDADGFRLAVSGLVTGQRSWSLPALYALPHAEQITRHICVEGWSAIGRWGGTPFREFLRRVGADTSAKYVGFKCADDYYESIDMATALHPQTLLAFEYDGKRLPPEYGFPMKLRMPTKLGYKNPKHIVEIFVTNAYPGGYWVDQGYNWFGGS
>NZ_LK936442.1|WP_160974052.1|1454806_1455019_+|hypothetical-protein
MLTKCGRHAAHVIIRVRLRVRSSPSVMFAAARSDLSFRTPPFPVIPVFPAPLAGGRIARRSTARRFTRAG
>NZ_LK936442.1|WP_004192284.1|1455022_1455958_+|EamA-family-transporter
MTPFDRFLAFVARHPPRLPQSRSGRVALALVFIYFAWGSTYLALHVALESFPPLLLSGLRNLLAGVGLFVFAMRRRPVRPTLVEIRNAALVGTMLVTMSSGLIALGMRTVSSGSAAVMVATVPLFATVIASVAGRRVTGGEWGAVALGMVGIVVLNSGGPSSPGSTLGSITVLAGALFWAGGAHLAARLALPHDLFLSTALQIGLGGAASTCIAWVLGERIGHVAWVPGAAFVYLMLAGTMAAYVAYGYLIRHTSPIIASSCMYVNPVVAVALGALLLGEPVTAATVIATIAILGSVGLSFVFDPARRRAQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LK936442_1	1.2\|1122437\|22\|NZ_LK936442\|CRISPRCasFinder	1122437-1122458	22	MF140416	Mycobacterium phage LastHope, complete genome	6359-6380	1	0.955
NZ_LK936442_1	1.2\|1122437\|22\|NZ_LK936442\|CRISPRCasFinder	1122437-1122458	22	MT114163	Mycobacterium phage Settecandela, complete genome	64638-64659	1	0.955
NZ_LK936442_1	1.2\|1122437\|22\|NZ_LK936442\|CRISPRCasFinder	1122437-1122458	22	MK937592	Mycobacterium phage Phrappuccino, complete genome	64638-64659	1	0.955
NZ_LK936442_1	1.1\|1122383\|22\|NZ_LK936442\|CRISPRCasFinder	1122383-1122404	22	NC_011758	Methylorubrum extorquens CM4 plasmid pCMU01, complete sequence	379897-379918	2	0.909
NZ_LK936442_1	1.2\|1122437\|22\|NZ_LK936442\|CRISPRCasFinder	1122437-1122458	22	NC_042031	Mycobacterium phage Anaya, complete sequence	7332-7353	2	0.909
NZ_LK936442_1	1.2\|1122437\|22\|NZ_LK936442\|CRISPRCasFinder	1122437-1122458	22	NC_042031	Mycobacterium phage Anaya, complete sequence	7341-7362	2	0.909
NZ_LK936442_1	1.2\|1122437\|22\|NZ_LK936442\|CRISPRCasFinder	1122437-1122458	22	MF347636	Streptomyces phage NootNoot, complete genome	102732-102753	3	0.864

1. spacer 1.2|1122437|22|NZ_LK936442|CRISPRCasFinder matches to MF140416 (Mycobacterium phage LastHope, complete genome) position: , mismatch: 1, identity: 0.955

gtgccttcggtgccttcggtgc	CRISPR spacer
gtgccttcggtgccgtcggtgc	Protospacer
************** *******

2. spacer 1.2|1122437|22|NZ_LK936442|CRISPRCasFinder matches to MT114163 (Mycobacterium phage Settecandela, complete genome) position: , mismatch: 1, identity: 0.955

gtgccttcggtgccttcggtgc	CRISPR spacer
gtgccttcggtgacttcggtgc	Protospacer
************ *********

3. spacer 1.2|1122437|22|NZ_LK936442|CRISPRCasFinder matches to MK937592 (Mycobacterium phage Phrappuccino, complete genome) position: , mismatch: 1, identity: 0.955

gtgccttcggtgccttcggtgc	CRISPR spacer
gtgccttcggtgacttcggtgc	Protospacer
************ *********

4. spacer 1.1|1122383|22|NZ_LK936442|CRISPRCasFinder matches to NC_011758 (Methylorubrum extorquens CM4 plasmid pCMU01, complete sequence) position: , mismatch: 2, identity: 0.909

atgccttcggcggcttcgatgc	CRISPR spacer
ttgcctccggcggcttcgatgc	Protospacer
 *****.***************

5. spacer 1.2|1122437|22|NZ_LK936442|CRISPRCasFinder matches to NC_042031 (Mycobacterium phage Anaya, complete sequence) position: , mismatch: 2, identity: 0.909

gtgccttcggtgccttcggtgc	CRISPR spacer
gtgccttcggtgccttcggtcg	Protospacer
********************

6. spacer 1.2|1122437|22|NZ_LK936442|CRISPRCasFinder matches to NC_042031 (Mycobacterium phage Anaya, complete sequence) position: , mismatch: 2, identity: 0.909

gtgccttcggtgccttcggtgc	CRISPR spacer
ccgccttcggtgccttcggtgc	Protospacer
 .********************

7. spacer 1.2|1122437|22|NZ_LK936442|CRISPRCasFinder matches to MF347636 (Streptomyces phage NootNoot, complete genome) position: , mismatch: 3, identity: 0.864

gtgccttcggtgccttcggtgc	CRISPR spacer
cgaccttcggtgccttcggtgc	Protospacer
  .*******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

155642 : 193232

Burkholderia_phage(70.0%)

portal,tail,holin,capsid,terminase,head,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015985037.1\|155642_158435_-	toprim domain-containing protein	A4JWQ8	Burkholderia_virus	0.0e+00	100.0
WP_004524471.1\|158446_158701_-	hypothetical protein	K4NZY7	Burkholderia_phage	4.5e-40	100.0
WP_004531070.1\|158697_159057_-	hypothetical protein	K4NXB4	Burkholderia_phage	1.1e-60	100.0
WP_004524469.1\|159059_159266_-	hypothetical protein	K4NZT3	Burkholderia_phage	2.7e-35	100.0
WP_004531069.1\|159434_159674_-	hypothetical protein	K4PAZ5	Burkholderia_phage	1.4e-35	100.0
WP_004524467.1\|159677_159872_-	hypothetical protein	K4NXL1	Burkholderia_phage	1.6e-26	100.0
WP_004524466.1\|159915_160113_-	hypothetical protein	K4NZY3	Burkholderia_phage	1.6e-29	100.0
WP_004549898.1\|160118_160337_-	hypothetical protein	K4NXB1	Burkholderia_phage	1.1e-34	100.0
WP_004524465.1\|160352_160898_-	Bro-N domain-containing protein	K4NZS9	Burkholderia_phage	7.8e-98	100.0
WP_004549899.1\|160983_161232_-	ogr/Delta-like zinc finger family protein	K4PAZ0	Burkholderia_phage	3.0e-41	100.0
WP_004549900.1\|161219_161516_-	phage DNA-binding protein	E5E3P2	Burkholderia_phage	5.4e-37	84.3
WP_004531068.1\|161519_161756_-	hypothetical protein	K4NZX7	Burkholderia_phage	2.4e-35	100.0
WP_004549901.1\|161839_162298_+	helix-turn-helix transcriptional regulator	K4NXA8	Burkholderia_phage	5.2e-79	100.0
WP_004549902.1\|162350_163073_+	hypothetical protein	K4NZS4	Burkholderia_phage	1.1e-126	100.0
WP_004549903.1\|163507_163939_+	hypothetical protein	A0A089FKT7	Burkholderia_phage	8.6e-76	100.0
WP_004552642.1\|163952_165053_-	phage late control D family protein	K4PAY4	Burkholderia_phage	3.6e-203	100.0
WP_009935906.1\|165052_165478_-\|tail	phage tail protein	A4JWS2	Burkholderia_virus	3.3e-72	99.3
WP_038773162.1\|165495_168456_-	hypothetical protein	A4JWX4	Burkholderia_virus	0.0e+00	99.9
WP_004552648.1\|168458_168572_-\|tail	GpE family phage tail protein	A0A089FGX3	Burkholderia_phage	5.4e-14	100.0
WP_004531064.1\|168580_168925_-\|tail	phage tail assembly protein	K4NXA3	Burkholderia_phage	1.0e-55	100.0
WP_004524455.1\|168982_169492_-\|tail	phage major tail tube protein	K4NZR9	Burkholderia_phage	4.9e-94	100.0
WP_038734274.1\|169507_170680_-\|tail	phage tail sheath protein	A4JWS7	Burkholderia_virus	3.4e-223	99.7
WP_004531062.1\|170735_171407_-\|tail	phage tail fiber assembly protein	K4NXJ9	Burkholderia_phage	3.0e-115	100.0
WP_009941338.1\|171423_173787_-	hypothetical protein	K4NZW8	Burkholderia_phage	0.0e+00	99.6
WP_009941339.1\|173797_174352_-\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	8.5e-100	99.5
WP_045140929.1\|174344_175250_-\|plate	baseplate assembly protein	A4JWY2	Burkholderia_virus	3.0e-163	99.7
WP_004531058.1\|175246_175609_-\|plate	bacteriophage baseplate assembly protein W	K4PAX6	Burkholderia_phage	1.7e-61	100.0
WP_045140930.1\|175605_176286_-\|plate	phage baseplate assembly protein V	K4NXJ5	Burkholderia_phage	1.4e-120	97.8
WP_004531056.1\|176459_177236_+	site-specific DNA-methyltransferase	K4NZW3	Burkholderia_phage	1.6e-149	100.0
WP_004534424.1\|177401_177905_-	hypothetical protein	K4NX96	Burkholderia_phage	2.8e-94	100.0
WP_045140931.1\|178058_178526_-	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	7.7e-78	98.7
WP_004531054.1\|178522_178939_-\|tail	phage tail protein	A4JWT7	Burkholderia_virus	3.3e-72	100.0
WP_009971799.1\|179043_179484_-	bacteriophage protein	K4NXJ2	Burkholderia_phage	3.8e-71	100.0
WP_009941345.1\|179480_180293_-	DUF3380 domain-containing protein	A4JWZ0	Burkholderia_virus	1.2e-150	100.0
WP_004524440.1\|180289_180562_-\|holin	phage holin family protein	K4NX91	Burkholderia_phage	8.8e-42	100.0
WP_004524439.1\|180563_180908_-	membrane protein	K4NZQ3	Burkholderia_phage	2.9e-50	100.0
WP_004524438.1\|180922_181129_-\|tail	tail protein X	K4PAW7	Burkholderia_phage	2.4e-31	100.0
WP_009971798.1\|181125_181377_-	hypothetical protein	A4JWZ4	Burkholderia_virus	7.6e-40	100.0
WP_004531050.1\|181376_181856_-\|head	head completion/stabilization protein	K4NZV5	Burkholderia_phage	5.8e-81	100.0
WP_004531049.1\|181955_182645_-\|terminase	terminase endonuclease subunit	K4NX86	Burkholderia_phage	2.5e-117	100.0
WP_004531048.1\|182641_183655_-\|capsid	phage major capsid protein, P2 family	K4NZP8	Burkholderia_phage	7.2e-190	100.0
WP_004532870.1\|183688_184498_-\|capsid	GPO family capsid scaffolding protein	A4JWU8	Burkholderia_virus	3.2e-148	100.0
WP_045140932.1\|184641_186411_+\|terminase	terminase ATPase subunit family protein	A4JWU9	Burkholderia_virus	0.0e+00	99.3
WP_015985030.1\|186407_187463_+\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	6.8e-207	100.0
WP_004524431.1\|187569_187842_+	BrnT family toxin	K4NX81	Burkholderia_phage	1.0e-45	100.0
WP_004524430.1\|187801_188074_+	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	6.3e-48	100.0
WP_076886789.1\|188878_189085_-	DUF2188 domain-containing protein	NA	NA	NA	NA
WP_045140935.1\|189488_190034_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_045141134.1\|190033_190402_-	helix-turn-helix transcriptional regulator	L7TKV7	Pseudomonas_virus	3.1e-18	50.0
WP_004190026.1\|191299_192034_+	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_004189241.1\|192127_192760_+	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004189793.1\|192779_193232_+	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8

DBSCAN-SWA_2

979283 : 990265

Streptococcus_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004526281.1\|979283_981398_-	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7
WP_004526282.1\|981707_982217_-	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	4.2e-13	42.2
WP_071810810.1\|982408_982627_-	hypothetical protein	NA	NA	NA	NA
WP_004189780.1\|982889_983468_-	pseudouridine synthase	NA	NA	NA	NA
WP_004189552.1\|983735_984995_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189626.1\|984967_985150_-	hypothetical protein	NA	NA	NA	NA
WP_004526283.1\|985162_986788_+	multicopper oxidase family protein	NA	NA	NA	NA
WP_004196460.1\|986917_987121_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|987653_987968_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196461.1\|987964_990265_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1

DBSCAN-SWA_3

1612707 : 1667563

uncultured_Caudovirales_phage(33.33%)

coat,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009970730.1\|1612707_1614558_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_045141004.1\|1614585_1616001_-	hypothetical protein	NA	NA	NA	NA
WP_004193592.1\|1616024_1616291_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_076848326.1\|1616550_1616778_-	hypothetical protein	NA	NA	NA	NA
WP_045141005.1\|1616811_1619628_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	5.7e-27	25.0
WP_004535790.1\|1619630_1620464_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_004538396.1\|1620600_1621164_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_009930792.1\|1621160_1621754_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_004546127.1\|1621750_1624159_+	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_045141006.1\|1624267_1627603_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004521767.1\|1627580_1628072_+	lipoprotein	NA	NA	NA	NA
WP_075018909.1\|1628388_1628928_+	hypothetical protein	NA	NA	NA	NA
WP_045141007.1\|1629160_1629403_+	hypothetical protein	NA	NA	NA	NA
WP_045141008.1\|1629420_1629726_+	hypothetical protein	NA	NA	NA	NA
WP_028359097.1\|1629738_1632579_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.4e-20	25.9
WP_004526759.1\|1632580_1633456_+	hypothetical protein	NA	NA	NA	NA
WP_004526760.1\|1633452_1636296_+	hypothetical protein	NA	NA	NA	NA
WP_004526762.1\|1637465_1637717_+	DUF1153 domain-containing protein	NA	NA	NA	NA
WP_111963064.1\|1637674_1638583_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_004526764.1\|1638626_1638872_+	hypothetical protein	NA	NA	NA	NA
WP_045141008.1\|1640822_1641128_+	hypothetical protein	NA	NA	NA	NA
WP_004526759.1\|1643963_1644839_+	hypothetical protein	NA	NA	NA	NA
WP_004526760.1\|1644835_1647679_+	hypothetical protein	NA	NA	NA	NA
WP_004526761.1\|1647796_1648717_+	hypothetical protein	NA	NA	NA	NA
WP_004526762.1\|1648847_1649099_+	DUF1153 domain-containing protein	NA	NA	NA	NA
WP_111963064.1\|1649056_1649965_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_004526764.1\|1650008_1650254_+	hypothetical protein	NA	NA	NA	NA
WP_076851599.1\|1650594_1650888_+	hypothetical protein	NA	NA	NA	NA
WP_076851597.1\|1651810_1652524_+	hypothetical protein	NA	NA	NA	NA
WP_009951519.1\|1653096_1653264_-	hypothetical protein	A0A0P0ZBS5	Stx2-converting_phage	9.5e-07	50.0
WP_009951521.1\|1653478_1653739_+	hypothetical protein	NA	NA	NA	NA
WP_004538387.1\|1654020_1654467_+	hypothetical protein	NA	NA	NA	NA
WP_009920905.1\|1655541_1656036_+	hypothetical protein	NA	NA	NA	NA
WP_004526772.1\|1656693_1657614_+	hypothetical protein	NA	NA	NA	NA
WP_004526773.1\|1657873_1659187_+	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_004191144.1\|1660080_1660350_+	hypothetical protein	NA	NA	NA	NA
WP_004193855.1\|1660613_1660895_-	H-NS histone family protein	NA	NA	NA	NA
WP_004526776.1\|1661362_1662346_-	amidohydrolase family protein	NA	NA	NA	NA
WP_004552892.1\|1662390_1663650_-	MFS transporter	NA	NA	NA	NA
WP_004196705.1\|1664093_1664987_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004531175.1\|1665324_1665546_+	hypothetical protein	NA	NA	NA	NA
WP_004526781.1\|1665803_1666349_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526782.1\|1666401_1666962_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526783.1\|1667038_1667563_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_4

2455519 : 2463707

Ralstonia_virus(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004527232.1\|2455519_2456629_+	class II histone deacetylase	A0A2K9L2T7	Tupanvirus	3.1e-37	31.6
WP_004193371.1\|2456823_2457447_+	phospholipase D family protein	NA	NA	NA	NA
WP_004527233.1\|2457573_2457756_-	hypothetical protein	NA	NA	NA	NA
WP_004550288.1\|2458691_2459153_+	avidin	NA	NA	NA	NA
WP_004521250.1\|2459213_2459462_+	immunity 52 family protein	A4PE26	Ralstonia_virus	4.6e-13	60.6
WP_004531416.1\|2459497_2459725_-	hypothetical protein	Q8W6S4	Burkholderia_virus	3.8e-22	75.8
WP_009937072.1\|2459978_2460374_+	hypothetical protein	NA	NA	NA	NA
WP_004527236.1\|2460654_2461080_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	3.8e-15	49.4
WP_004527237.1\|2461076_2461583_+	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	5.1e-19	40.1
WP_038763587.1\|2461924_2462527_+	hypothetical protein	NA	NA	NA	NA
WP_004534826.1\|2462533_2463259_+	immunity 52 family protein	A4PE26	Ralstonia_virus	1.7e-31	43.5
WP_004535518.1\|2463443_2463707_-	hypothetical protein	Q8W6S4	Burkholderia_virus	5.0e-26	85.5

DBSCAN-SWA_5

2981718 : 2990615

Tanapox_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004547474.1\|2981718_2982561_+	alpha/beta hydrolase	A7XCB7	Tanapox_virus	5.5e-18	27.0
WP_004188957.1\|2982903_2983827_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	8.4e-44	36.5
WP_045141079.1\|2984005_2985313_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004532363.1\|2985539_2986442_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_038720484.1\|2986453_2986696_-	hypothetical protein	NA	NA	NA	NA
WP_004189725.1\|2986819_2987137_-	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_004190173.1\|2987208_2988201_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_009921652.1\|2988259_2989183_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.3e-15	27.1
WP_004522358.1\|2989214_2990615_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.9e-79	38.5

DBSCAN-SWA_6

3327622 : 3336866

unidentified_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045141093.1\|3327622_3329170_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	9.5e-24	30.9
WP_004194373.1\|3329206_3329734_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004532195.1\|3329730_3330414_+	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.0e-05	26.0
WP_004194137.1\|3330478_3331294_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_045141094.1\|3331477_3333484_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	2.2e-52	34.8
WP_004533593.1\|3333517_3334648_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	3.8e-22	27.6
WP_004194034.1\|3334913_3336866_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2

DBSCAN-SWA_7

3621612 : 3675741

Burkholderia_phage(44.44%)

tail,tRNA,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004521984.1\|3621612_3622911_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_004527811.1\|3622977_3624060_+	peptide chain release factor 1	A0A0S4KWG0	Pseudomonas_phage	6.7e-08	46.6
WP_004534980.1\|3624103_3624961_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_004186955.1\|3625040_3625349_+	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_004521981.1\|3625363_3625960_+	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_004521980.1\|3626243_3627032_+	dioxygenase	NA	NA	NA	NA
WP_004527813.1\|3627397_3628999_-	APC family permease	NA	NA	NA	NA
WP_004196837.1\|3629432_3629636_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.3e-21	73.1
WP_004198058.1\|3629822_3631085_-	Hsp70 family protein	NA	NA	NA	NA
WP_004198059.1\|3631792_3632398_-	nitroreductase family protein	NA	NA	NA	NA
WP_004198060.1\|3632359_3632935_+	hypothetical protein	NA	NA	NA	NA
WP_004198061.1\|3632894_3634178_-	MFS transporter	NA	NA	NA	NA
WP_038729191.1\|3634336_3634981_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004527819.1\|3635318_3635942_+	DUF1415 domain-containing protein	NA	NA	NA	NA
WP_004527820.1\|3636026_3636929_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004527821.1\|3637056_3638193_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004198068.1\|3638361_3638475_+	hypothetical protein	NA	NA	NA	NA
WP_004521968.1\|3638549_3639668_-	acyltransferase	NA	NA	NA	NA
WP_004527823.1\|3639666_3640146_+	hypothetical protein	NA	NA	NA	NA
WP_004199982.1\|3640105_3640609_-	LEA type 2 family protein	NA	NA	NA	NA
WP_004204896.1\|3641212_3643378_+	peptidase	A0A0P0IY26	Acinetobacter_phage	1.9e-46	27.1
WP_004185238.1\|3644433_3644670_+	hypothetical protein	NA	NA	NA	NA
WP_004204906.1\|3644772_3645003_+	hypothetical protein	NA	NA	NA	NA
WP_004199991.1\|3645618_3646887_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004521963.1\|3646901_3649163_+	peptidase domain-containing ABC transporter	A0A2R8FG22	Brazilian_cedratvirus	2.3e-10	31.9
WP_004527831.1\|3649159_3650608_+	TolC family protein	NA	NA	NA	NA
WP_004521960.1\|3650817_3651786_-	hypothetical protein	NA	NA	NA	NA
WP_004199998.1\|3651911_3652763_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_009971107.1\|3653041_3656935_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004200003.1\|3656931_3657921_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004527834.1\|3657925_3658858_+	OmpA family protein	NA	NA	NA	NA
WP_004527835.1\|3659049_3660171_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004202807.1\|3660260_3662930_-	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	3.8e-89	32.0
WP_004200010.1\|3662963_3664064_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004527836.1\|3664027_3665866_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004204912.1\|3665945_3666428_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004527837.1\|3666485_3666989_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004521953.1\|3667061_3668552_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004521952.1\|3668568_3669087_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004531875.1\|3669123_3669795_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004521950.1\|3670168_3670783_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004521949.1\|3670891_3672238_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004521948.1\|3672234_3673020_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004527840.1\|3673121_3673487_+	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	2.5e-52	88.4
WP_038738600.1\|3674508_3674991_-	site-specific DNA-methyltransferase	K4NZW3	Burkholderia_phage	7.7e-73	87.6
WP_004527843.1\|3675008_3675422_-\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	8.0e-71	100.0
WP_004527844.1\|3675414_3675741_-\|plate	baseplate assembly protein	K4NZR5	Burkholderia_phage	6.6e-52	98.1

DBSCAN-SWA_8

3937933 : 3949162

Burkholderia_phage(22.22%)

integrase

attL 3935138:3935155|attR 3951741:3951758

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3935138:3935155	attL	NA	NA	NA	NA
WP_004195754.1\|3937933_3938578_-	lytic polysaccharide monooxygenase	A0A0K1Y848	Apis_mellifera_filamentous_virus	5.7e-07	30.4
WP_004525721.1\|3939478_3939727_-	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	4.0e-41	97.6
WP_004525722.1\|3939883_3940963_-	DUF3396 domain-containing protein	A9YX32	Burkholderia_phage	2.2e-160	99.0
WP_009932249.1\|3940962_3941415_-	VRR-NUC domain-containing protein	Q8W6S1	Burkholderia_virus	2.3e-31	58.8
WP_045141125.1\|3941672_3942215_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	1.4e-46	55.2
WP_050856610.1\|3942468_3943386_-	DUF4935 domain-containing protein	A4PE40	Ralstonia_virus	1.5e-45	40.2
WP_024430280.1\|3943385_3943703_-	helix-turn-helix transcriptional regulator	A0A088CD40	Shigella_phage	3.7e-15	57.0
WP_076841780.1\|3944082_3944670_-\|integrase	site-specific integrase	A0A0S2SYQ7	Pseudomonas_phage	3.8e-42	48.9
WP_004552489.1\|3945852_3946752_+	cytochrome	NA	NA	NA	NA
WP_045141127.1\|3947074_3949162_-	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	2.4e-99	35.8
3951741:3951758	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_LK936443

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_LK936443_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LK936443_1

3008582-3008727

Orphan

Consensus_repeat	Method
GCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCGAAG	PILER-CR
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_LK936443_1

>merge|NZ_LK936443|1|3008582-3008727|PILER-CR,CRISPRCasFinder
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCG

>NZ_LK936443|1|1|3008582-3008727|PILER-CR
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAA	TGCCCGAT
CATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAAT	ACCCGATCA
TCGGGATGCTCGATCGCCG

>NZ_LK936443|1|1|3008632-3008717|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LK936443.1\|WP_004548017.1\|3002309_3002900_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LK936443.1\|WP_004530666.1\|3015026_3016058_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|236122
NZ_LK936443.1\|WP_004530665.1\|3016054_3017887_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NZ_LK936443.1\|WP_162187268.1\|3020795_3021926_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_LK936443.1\|WP_004523292.1\|2996718_2997951_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NZ_LK936443.1\|WP_045141341.1\|3001358_3002294_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NZ_LK936443.1\|WP_004530670.1\|3005147_3007421_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NZ_LK936443.1\|WP_004523282.1\|3010774_3012616_+\|ribonucleotide-reductase	unknown	unknown	gnl\|CDD\|180772
NZ_LK936443.1\|WP_004547976.1\|3002959_3004858_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_LK936443.1\|WP_004529498.1\|3019955_3020390_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NZ_LK936443.1\|WP_004530664.1\|3018008_3018338_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LK936443.1\|WP_045141342.1\|3009294_3010572_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NZ_LK936443.1\|WP_004188282.1\|2995669_2996713_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_LK936443.1\|WP_004200705.1\|3019234_3019888_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NZ_LK936443.1\|WP_004545434.1\|3012690_3014502_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NZ_LK936443.1\|WP_004532554.1\|2994216_2995668_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001
NZ_LK936443.1\|WP_004187469.1\|3007553_3007949_-\|TraR/DksA-C4-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|224648
NZ_LK936443.1\|WP_004200700.1\|2999945_3001061_-\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|378454
NZ_LK936443.1\|WP_004530663.1\|3018341_3018791_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NZ_LK936443.1\|WP_004529483.1\|2999203_2999644_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863

Protein	Function_ID	Function_description	E-value
NZ_LK936443.1\|WP_004545434.1\|3012690_3014502_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	3.42956e-75
NZ_LK936443.1\|WP_004530666.1\|3015026_3016058_+\|nitroreductase-family-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	7.9992e-31
NZ_LK936443.1\|WP_004530665.1\|3016054_3017887_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.21999e-106
NZ_LK936443.1\|WP_162187268.1\|3020795_3021926_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	3.20506e-55
NZ_LK936443.1\|WP_004523292.1\|2996718_2997951_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	5.32689e-143
NZ_LK936443.1\|WP_045141341.1\|3001358_3002294_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.10899e-62
NZ_LK936443.1\|WP_004530670.1\|3005147_3007421_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	1.88074e-56
NZ_LK936443.1\|WP_004523282.1\|3010774_3012616_+\|ribonucleotide-reductase	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NZ_LK936443.1\|WP_004547976.1\|3002959_3004858_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	5.29917e-35
NZ_LK936443.1\|WP_004529498.1\|3019955_3020390_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	9.00264e-33
NZ_LK936443.1\|WP_004200705.1\|3019234_3019888_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	6.31252e-20
NZ_LK936443.1\|WP_045141342.1\|3009294_3010572_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	3.02118e-112
NZ_LK936443.1\|WP_004188282.1\|2995669_2996713_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NZ_LK936443.1\|WP_004532554.1\|2994216_2995668_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	2.41184e-132
NZ_LK936443.1\|WP_004187469.1\|3007553_3007949_-\|TraR/DksA-C4-type-zinc-finger-protein	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NZ_LK936443.1\|WP_004200700.1\|2999945_3001061_-\|SRPBCC-family-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11
NZ_LK936443.1\|WP_004530663.1\|3018341_3018791_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	3.14402e-50
NZ_LK936443.1\|WP_004529483.1\|2999203_2999644_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.19676e-25

>NZ_LK936443.1|WP_004187469.1|3007553_3007949_-|TraR/DksA-C4-type-zinc-finger-protein
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NZ_LK936443.1|WP_004530670.1|3005147_3007421_-|FAD-dependent-oxidoreductase
MREFDYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYVAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPDVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKTKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGCDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NZ_LK936443.1|WP_004547976.1|3002959_3004858_+|GMC-family-oxidoreductase
MLGATRSTLWGSRERPRIAAARAPGAAAIRMREEARECAGPRGAGRAPHRATAAGGKTGRRTVRAPSRARAGSNNQKVNRMKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLRGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPDKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWRMIDPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NZ_LK936443.1|WP_004548017.1|3002309_3002900_+|hypothetical-protein
MCRARGIGRQARGNATAPSPIAAAAIGARPRSAPRGPRISDAGRLAAARSAFAMHQERRKRNADRHGTHPYDADSRAAPREAPRFEHEPKKQRDAAQHEVDRDRAAREIRERIEHKARPDVRRAERPISQDVAQTPIGAAGAISPSTAHSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NZ_LK936443.1|WP_045141341.1|3001358_3002294_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYSLQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>NZ_LK936443.1|WP_004200700.1|2999945_3001061_-|SRPBCC-family-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NZ_LK936443.1|WP_004529483.1|2999203_2999644_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDEHRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NZ_LK936443.1|WP_004523292.1|2996718_2997951_-|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDEHGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHTLALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSISGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPTLIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAALEAEVLAAQKEAERYGTLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
>NZ_LK936443.1|WP_004188282.1|2995669_2996713_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTASKEGPAASPMTMIQALRSAMDVMLERDGNVVVFGQDVGYFGGVFRCTEGLQNKYGKSRVFDAPINEGGIVGAAVGMGAYGLRPVCEIQFADYFYPASDQIVSEAARLRYRSAAEFIAPLTIRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLISAIENDDPVIFLEPKRLYNGPFDGHHERPVTPWSKHPASLVPDGYYTVPLDSAAIVRAGGDVTVLTYGTTVHVSLAAAEETGIDAEVIDLRSLWPLDLDTIVESVRRTGRCVVVHEATRTCGFGAELIALVQEHCFHWLEAPVERVTGWDTPYPHAQEWAYFPGPNRVGDALRRAMEN
>NZ_LK936443.1|WP_004532554.1|2994216_2995668_-|2-oxo-acid-dehydrogenase-subunit-E2
MGVHVIKMPDIGEGIAEVELGLWHVKVGDRVKEDQAIADVMTDKASVEIPSPVTGVVVALGGKEGDVLAVGSELVRLEVEGDGNHKAEPDGGARAAAAQPERVADTAHAHASAAAKSARGEHGAGHGRDDARAASSGTSSGASHTQHAEREARGHRESSEYREDRSVSRGASQTDVERGPASPPPARRPGERPLASPAVRKRAWDLGVELRYVHGTGEAGRILHEDLDAYLQGRGAAAQRARGGQAAYVERHDEEAVPVIGLRRKIAQRMQDAKRRIPHFSYVEEIDVTELEALRAELNRKYGDTRGRLTVLPLLARAMVIALREFPQINARYDDEAGVVTRHGAVHLGIATQSKAGLMVPVVRHAEARDPWSIAAEVARLADAARAGRAERDELSGSTITITSLGALGGIASTPVINSPEVGIVGVNRIVERPMFRGGAVVARKLMNLSSSFDHRVIDGMDAAEFIQAVRGLLEQPALLFVE
>NZ_LK936443.1|WP_045141342.1|3009294_3010572_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRACQPWAGAAQRAGAGAGAGARPAGWPTWGPMARAADAVPAPPPFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPPEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWAAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPRRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NZ_LK936443.1|WP_004523282.1|3010774_3012616_+|ribonucleotide-reductase
MRTINKRTRTIAHADSFVRMIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIGATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NZ_LK936443.1|WP_004545434.1|3012690_3014502_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFSELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGTAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLERALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDHSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDALDAARVDAQATR
>NZ_LK936443.1|WP_004530666.1|3015026_3016058_+|nitroreductase-family-protein
METSPLKTTTPEAIPPFDPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGLAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVAAGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NZ_LK936443.1|WP_004530665.1|3016054_3017887_+|STAS-domain-containing-protein
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDCSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLVAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEADAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NZ_LK936443.1|WP_004530664.1|3018008_3018338_-|hypothetical-protein
MLSSRLVSSRLAPCCVYIDIQGEGDVDVDAEGNGNGNIDVIDSKRCEPSGVEPVERAVRRPRYRAQSGCLSGIHRNGIVMPDPMPPTNRFDRLRASAVIVDRMKPRRSP
>NZ_LK936443.1|WP_004530663.1|3018341_3018791_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKDVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NZ_LK936443.1|WP_004200705.1|3019234_3019888_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDIYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NZ_LK936443.1|WP_004529498.1|3019955_3020390_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFQGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NZ_LK936443.1|WP_162187268.1|3020795_3021926_-|porin
MMNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLSTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGASLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

83084 : 148999

Ralstonia_phage(28.57%)

holin,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024431811.1\|83084_85280_+\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA
WP_023358215.1\|87069_88239_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.9e-32	30.1
WP_080002191.1\|89590_89845_+	SET domain-containing protein-lysine N-methyltransferase	NA	NA	NA	NA
WP_045141157.1\|89841_90861_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004533753.1\|90880_91333_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_038736600.1\|91892_92738_+	ABC transporter permease	NA	NA	NA	NA
WP_023358505.1\|92724_93576_+	ABC transporter permease	NA	NA	NA	NA
WP_004552621.1\|93572_94604_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_004545027.1\|95191_95497_+	H-NS histone family protein	NA	NA	NA	NA
WP_038724231.1\|95817_98583_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.6e-88	34.8
WP_041223210.1\|98596_100837_+	DUF3274 domain-containing protein	A0A077K801	Ralstonia_phage	6.8e-23	27.4
WP_004537686.1\|100855_102514_+	DUF2875 family protein	NA	NA	NA	NA
WP_004523722.1\|102523_102787_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_004537437.1\|102937_103222_+	hypothetical protein	NA	NA	NA	NA
WP_004523721.1\|103201_103621_-	YjbQ family protein	NA	NA	NA	NA
WP_004523720.1\|103640_103967_-	thioredoxin family protein	NA	NA	NA	NA
WP_004531587.1\|104438_105131_+	hypothetical protein	NA	NA	NA	NA
WP_004531586.1\|105716_106448_-	DUF2244 domain-containing protein	NA	NA	NA	NA
WP_004523716.1\|106444_108040_-	cytochrome c oxidase subunit I	R9VX24	Flavobacterium_phage	1.9e-06	33.3
WP_024431977.1\|109189_110647_-	hypothetical protein	NA	NA	NA	NA
WP_153260193.1\|110991_111351_-	hypothetical protein	NA	NA	NA	NA
WP_050882081.1\|112199_114305_+	YadA-like family protein	A0A2C9CZG8	Yersinia_phage	4.9e-07	46.1
WP_009971259.1\|114371_115823_-	PhoPQ-regulated protein	NA	NA	NA	NA
WP_004523708.1\|115894_116110_+	hypothetical protein	NA	NA	NA	NA
WP_011326446.1\|116120_116675_-	membrane protein	NA	NA	NA	NA
WP_004533867.1\|117259_117805_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_004529635.1\|117884_118607_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_004538930.1\|118767_121464_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004529637.1\|121456_122029_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_004531579.1\|122060_122750_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004531578.1\|122752_124429_+	OmpA family protein	NA	NA	NA	NA
WP_004523700.1\|124818_125358_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004523699.1\|125391_126891_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004529642.1\|127090_127573_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004529643.1\|127700_128243_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004523698.1\|128248_129598_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004531577.1\|129594_130896_+	type VI secretion system protein TssL	NA	NA	NA	NA
WP_004529645.1\|130910_134819_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004553076.1\|135008_135578_+	hypothetical protein	NA	NA	NA	NA
WP_041281455.1\|135675_138288_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.1e-35	26.0
WP_004523693.1\|138362_138632_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_004529649.1\|138644_142097_+	RHS repeat protein	NA	NA	NA	NA
WP_004531572.1\|141989_143348_-	hypothetical protein	A0A292GJ55	Xanthomonas_phage	3.4e-110	45.2
WP_004529650.1\|143380_144409_-	fimbrial protein	NA	NA	NA	NA
WP_045141158.1\|144463_145534_-	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_004544916.1\|145552_146602_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_038718045.1\|146598_148479_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004523686.1\|148480_148999_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_2

687964 : 759407

Vibrio_phage(25.0%)

holin,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004525541.1\|687964_688732_-\|holin	phosphocholine cytidylyltransferase family protein	NA	NA	NA	NA
WP_004206084.1\|688770_689772_-	HpnL family protein	NA	NA	NA	NA
WP_004530788.1\|689768_690542_-	hypothetical protein	NA	NA	NA	NA
WP_004188272.1\|690538_691228_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_004188420.1\|691592_693107_+	acetyl-CoA hydrolase/transferase family protein	NA	NA	NA	NA
WP_004530037.1\|694816_695755_+	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_004202234.1\|695788_696337_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190846.1\|696339_697845_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004530039.1\|697988_698516_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004190879.1\|698595_699027_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_045141184.1\|699040_700903_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190851.1\|700899_701889_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004530040.1\|701891_704762_+	type VI secretion system ATPase TssH	A0A2I7REQ1	Vibrio_phage	2.4e-60	27.2
WP_004525548.1\|704752_707044_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004190563.1\|707209_709498_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004530041.1\|709501_711718_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004525550.1\|711717_712788_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004530790.1\|712790_713507_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004190606.1\|713549_713939_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004202226.1\|713944_714538_+	type VI secretion lipoprotein TssJ	NA	NA	NA	NA
WP_004525552.1\|714534_715896_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_045141185.1\|715978_717637_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004525554.1\|717633_721137_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190863.1\|721195_721555_+	hypothetical protein	NA	NA	NA	NA
WP_004190471.1\|721577_722003_+	hypothetical protein	NA	NA	NA	NA
WP_004536812.1\|722323_722599_+	hypothetical protein	NA	NA	NA	NA
WP_004528661.1\|723149_724049_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004542286.1\|724090_724381_-	hypothetical protein	NA	NA	NA	NA
WP_004524287.1\|724270_725590_+	glycosyltransferase	NA	NA	NA	NA
WP_004524286.1\|725586_727173_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_024431748.1\|727402_728398_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_038724161.1\|728523_728706_+	hypothetical protein	NA	NA	NA	NA
WP_011326084.1\|728702_730286_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004186853.1\|730766_732020_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004530050.1\|732532_734197_-	glycoside hydrolase family 32 protein	F8WPR5	Bacillus_phage	4.1e-57	31.6
WP_004186967.1\|734329_735814_-	glycoside hydrolase family 68 protein	NA	NA	NA	NA
WP_004530800.1\|736083_737100_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_004523135.1\|737561_738761_+	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	8.4e-12	27.2
WP_004198247.1\|738938_739964_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_160457400.1\|739977_740262_+	hypothetical protein	NA	NA	NA	NA
WP_004545861.1\|740397_741672_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	5.3e-105	54.1
WP_004186989.1\|741744_742716_+	membrane dipeptidase	NA	NA	NA	NA
WP_004186987.1\|742866_743400_+	4-vinyl reductase	NA	NA	NA	NA
WP_004186960.1\|743460_745524_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_004186901.1\|745526_747452_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004523138.1\|747456_748629_+	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004530055.1\|748625_749411_+	drug:proton antiporter	NA	NA	NA	NA
WP_004523139.1\|749435_750704_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004530056.1\|750724_751870_+	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004523141.1\|751979_752843_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004530057.1\|753023_754679_+	APC family permease	NA	NA	NA	NA
WP_004186920.1\|754765_755641_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_004554841.1\|755784_756657_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004537371.1\|756819_758373_+\|holin	choline-sulfatase	NA	NA	NA	NA
WP_004530058.1\|758369_759407_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

DBSCAN-SWA_3

2733888 : 2793172

Ralstonia_phage(22.22%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004539275.1\|2733888_2734617_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.2e-21	31.2
WP_162187271.1\|2735439_2737200_-	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_009941131.1\|2737720_2738050_-	hypothetical protein	NA	NA	NA	NA
WP_045141371.1\|2738056_2747059_-	hemagglutinin repeat-containing protein	NA	NA	NA	NA
WP_085952178.1\|2747101_2748212_+\|transposase	IS3-like element ISBp1 family transposase	NA	NA	NA	NA
WP_050858995.1\|2748160_2748580_-	hypothetical protein	NA	NA	NA	NA
WP_004546318.1\|2748731_2748929_-	hypothetical protein	NA	NA	NA	NA
WP_004529300.1\|2748929_2749193_-	putative Immunity protein 75	NA	NA	NA	NA
WP_045141328.1\|2749784_2754443_-	type IV secretion protein Rhs	A0A2H4JFP5	uncultured_Caudovirales_phage	8.3e-23	34.9
WP_004553667.1\|2754429_2755698_-	hypothetical protein	NA	NA	NA	NA
WP_009935222.1\|2755713_2757918_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.7e-42	28.0
WP_045141329.1\|2759374_2760364_-	DUF1016 family protein	A0A0U2BZN7	Salmonella_phage	3.9e-23	43.4
WP_024431044.1\|2761377_2761845_+	decarboxylase	NA	NA	NA	NA
WP_009972369.1\|2762000_2763026_+	hypothetical protein	NA	NA	NA	NA
WP_004539266.1\|2763589_2764189_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_004524853.1\|2764213_2764624_-	RidA family protein	NA	NA	NA	NA
WP_004530174.1\|2766053_2766401_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	72.0
WP_004539264.1\|2766397_2766805_-\|transposase	transposase	A0A0P0ZCV4	Stx2-converting_phage	2.4e-11	36.5
WP_045141330.1\|2767237_2769271_-	hypothetical protein	NA	NA	NA	NA
WP_004546333.1\|2769511_2771683_-	alpha-galactosidase	NA	NA	NA	NA
WP_004524829.1\|2771687_2772539_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_004524828.1\|2772539_2773463_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_004524827.1\|2773525_2774767_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_004524825.1\|2774802_2776047_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	7.1e-22	32.8
WP_024431041.1\|2776089_2776728_-	hypothetical protein	NA	NA	NA	NA
WP_143284288.1\|2777562_2778150_-	hypothetical protein	NA	NA	NA	NA
WP_011326322.1\|2778500_2779655_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_004524822.1\|2780997_2781738_+	hypothetical protein	NA	NA	NA	NA
WP_024431039.1\|2782469_2783729_-	DUF746 domain-containing protein	NA	NA	NA	NA
WP_004529319.1\|2783688_2784399_-	hypothetical protein	NA	NA	NA	NA
WP_004203275.1\|2784414_2786619_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004529320.1\|2786615_2789282_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	1.8e-78	30.7
WP_004529321.1\|2789260_2790739_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004529322.1\|2790735_2792607_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004196148.1\|2792611_2793172_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LK936442

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_LK936443

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection