CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LM997411	Methylacidiphilum fumariolicum SolV genome assembly MfumSolVChr1, chromosome : Strain_SolV_genome_(final)	2 crisprs	cas7,cas8u2,cas3,c2c9_V-U4,cas14k,DinG,csx3,Cas9_archaeal,cmr1gr7,csx1,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,cas1,cas2	0	1	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LM997411_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LM997411_1

261074-261396

Unclear

Consensus_repeat	Method
AGCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	CRISPRCasFinder
CTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	CRT
AACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	PILER-CR

4 spacers

csb2gr5,cas7,cas8u2,cas3

The CRISPR arrays of NZ_LM997411_1

>merge|NZ_LM997411|1|261074-261396|CRISPRCasFinder,CRT,PILER-CR
AGTTCCAATGAAGCCTCAGCTCTTCAGCTGAGGGAACCATCTTTCCTCCTTCCTGGCCACACATTGGCCAATCCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAACCATCCAGGTGGTATTCCTTCCAGCATGGCAGAAAACCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAACTGATTTTAGGCCTGGCATGGAAGTCAGTCATGGCAAGCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAACGATTAGAACTGATAACCATAAAATTCAATGACAGGAGCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC

>NZ_LM997411|1|1|261074-261396|CRISPRCasFinder
AGTTCCAATGAAGCCTCAGCTCTTCAGCTGAGGGAAC	CATCTTTCCTCCTTCCTGGCCACACATTGGCCAA
TCCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	CATCCAGGTGGTATTCCTTCCAGCATGGCAGAAA
ACCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	TGATTTTAGGCCTGGCATGGAAGTCAGTCATGGCA
AGCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	GATTAGAACTGATAACCATAAAATTCAATGACAGG
AGCTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC

>NZ_LM997411|1|1|261076-261396|CRT
TTCCAATGAAGCCTCAGCTCTTCAGCTGAGGGAAC	CATCTTTCCTCCTTCCTGGCCACACATTGGCCAATC
CTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	CATCCAGGTGGTATTCCTTCCAGCATGGCAGAAAAC
CTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	TGATTTTAGGCCTGGCATGGAAGTCAGTCATGGCAAG
CTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	GATTAGAACTGATAACCATAAAATTCAATGACAGGAG
CTTAAACGAAGCCTCAGCTCTTCAGCTGAGGGAAC

>NZ_LM997411|1|1|261080-261396|PILER-CR
AATGAAGCCTCAGCTCTTCAGCTGAGGGAAC	CATCTTTCCTCCTTCCTGGCCACACATTGGCCAATCCTTA
AACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	CATCCAGGTGGTATTCCTTCCAGCATGGCAGAAAACCTTA
AACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	TGATTTTAGGCCTGGCATGGAAGTCAGTCATGGCAAGCTTA
AACGAAGCCTCAGCTCTTCAGCTGAGGGAAC	GATTAGAACTGATAACCATAAAATTCAATGACAGGAGCTTA
AACGAAGCCTCAGCTCTTCAGCTGAGGGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LM997411.1\|WP_045086442.1\|258772_260392_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_LM997411.1\|WP_009062036.1\|264850_267346_-\|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl\|CDD\|274235
NZ_LM997411.1\|WP_045086441.1\|258326_258605_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LM997411.1\|WP_009062068.1\|247252_248431_-\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	unknown	unknown	gnl\|CDD\|235571
NZ_LM997411.1\|WP_009062038.1\|264074_264854_-\|hypothetical-protein	cas8u2	cd09765_cas8u2_CAS-I-U	gnl\|CDD\|187734
NZ_LM997411.1\|WP_009062062.1\|253507_254329_-\|GTP-cyclohydrolase-I-FolE2	unknown	unknown	gnl\|CDD\|376879
NZ_LM997411.1\|WP_009062057.1\|255825_256515_+\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|223710
NZ_LM997411.1\|WP_009062066.1\|248472_251241_-\|2-oxoglutarate-dehydrogenase-E1-component	unknown	unknown	gnl\|CDD\|236499
NZ_LM997411.1\|WP_009062024.1\|270415_271180_-\|Zn-finger-protein	unknown	unknown	unknown
NZ_LM997411.1\|WP_009062022.1\|271179_271422_-\|polymer-forming-cytoskeletal-protein	unknown	unknown	gnl\|CDD\|377376
NZ_LM997411.1\|WP_009062048.1\|260468_260837_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LM997411.1\|WP_045086438.1\|254538_255840_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133150
NZ_LM997411.1\|WP_079199499.1\|269945_270098_-\|small-basic-protein	unknown	unknown	gnl\|CDD\|275006
NZ_LM997411.1\|WP_045086443.1\|262954_263161_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LM997411.1\|WP_009062064.1\|251334_253257_-\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NZ_LM997411.1\|WP_009062029.1\|268556_268898_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LM997411.1\|WP_009062055.1\|256550_257444_+\|ChaN-family-lipoprotein	unknown	unknown	gnl\|CDD\|377239
NZ_LM997411.1\|WP_045086445.1\|267961_268336_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LM997411.1\|WP_009062043.1\|261576_262935_-\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl\|CDD\|274005
NZ_LM997411.1\|WP_009062039.1\|263294_264062_-\|type-I-U-CRISPR-associated-protein-Cas7	cas7	cd09738_cas7_CAS-I-U	gnl\|CDD\|187869

Protein	Function_ID	Function_description	E-value
NZ_LM997411.1\|WP_045086442.1\|258772_260392_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.18193e-20
NZ_LM997411.1\|WP_009062036.1\|264850_267346_-\|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|274235	TIGR02621, CRISPR-associated_helicase_Cas3, CRISPR-associated helicase Cas3, subtype Dpsyc. This model describes a CRISPR-associated putative DEAH-box helicase, or Cas3, of a subtype found in Actinomyces naeslundii MG1, Geobacter sulfurreducens PCA, Gemmata obscuriglobus UQM 2246, and Desulfotalea psychrophila. This protein includes both DEAH and HD motifs.	2.47033e-144
NZ_LM997411.1\|WP_009062068.1\|247252_248431_-\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	gnl\|CDD\|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	1.02518e-166
NZ_LM997411.1\|WP_009062062.1\|253507_254329_-\|GTP-cyclohydrolase-I-FolE2	gnl\|CDD\|376879	pfam02649, GCHY-1, Type I GTP cyclohydrolase folE2. This is a family of prokaryotic proteins with type I GTP cyclohydrolase activity. GTP cyclohydrolase I is the first enzyme of the de novo tetrahydrofolate biosynthetic pathway present in bacteria, fungi, and plants, and encoded in Escherichia coli by the folE gene; it is also the first enzyme of the biopterin (BH4) pathway in Homo sapiens. The invariate, highly conserved glutamate residue at position 216 in Neisseria gonorrhoeae FolE2 is likely to be the substrate ligand and the metal ligand is likely to be the cysteine at position 147. The enzyme is Zinc 2+ dependent.	2.22509e-127
NZ_LM997411.1\|WP_009062038.1\|264074_264854_-\|hypothetical-protein	gnl\|CDD\|187734	cd09765, Csx14_I-U, CRISPR/Cas system-associated protein Csx14. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein containing C-terminal alpha-helical domain resembling Cas8a2, also known as GSU0052.	2.31909e-13
NZ_LM997411.1\|WP_009062057.1\|255825_256515_+\|HAD-family-phosphatase	gnl\|CDD\|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	2.76929e-61
NZ_LM997411.1\|WP_009062066.1\|248472_251241_-\|2-oxoglutarate-dehydrogenase-E1-component	gnl\|CDD\|236499	PRK09404, sucA, 2-oxoglutarate dehydrogenase E1 component; Reviewed.	0
NZ_LM997411.1\|WP_009062022.1\|271179_271422_-\|polymer-forming-cytoskeletal-protein	gnl\|CDD\|377376	pfam04519, Bactofilin, Polymer-forming cytoskeletal. This is a family of bactofilins, a functionally diverse class of cytoskeletal, polymer-forming, proteins that is widely conserved among bacteria. In the example species C. crescentus, two bactofilins assemble into a membrane-associated laminar structure that shows cell-cycle-dependent polar localization and acts as a platform for the recruitment of a cell wall biosynthetic enzyme involved in polar morphogenesis. Bactofilins display distinct subcellular distributions and dynamics in different bacterial species, suggesting that they are versatile structural elements that have adopted a range of different cellular functions.	1.28659e-08
NZ_LM997411.1\|WP_045086438.1\|254538_255840_-\|hypothetical-protein	gnl\|CDD\|133150	cd05483, retropepsin_like_bacteria, Bacterial aspartate proteases, retropepsin-like protease family. This family of bacteria aspartate proteases is a subfamily of retropepsin-like protease family, which includes enzymes from retrovirus and retrotransposons. While fungal and mammalian pepsin-like aspartate proteases are bilobal proteins with structurally related N- and C-termini, this family of bacteria aspartate proteases is half as long as their fungal and mammalian counterparts. The monomers are structurally related to one lobe of the pepsin molecule and function as homodimers. The active site aspartate occurs within a motif (Asp-Thr/Ser-Gly), as it does in pepsin. In aspartate peptidases, Asp residues are ligands of an activated water molecule in all examples where catalytic residues have been identified. This group of aspartate proteases is classified by MEROPS as the peptidase family A2 (retropepsin family, clan AA), subfamily A2A.	3.96504e-17
NZ_LM997411.1\|WP_079199499.1\|269945_270098_-\|small-basic-protein	gnl\|CDD\|275006	TIGR04137, hypothetical_protein, Chlam_Verruc_Plancto small basic protein. Members of this protein family are commonly found next to markers of rRNA processing such as YbeY. They are extremely lineage-restricted, in the Planctomycetes and Chlamydiae/Verrucomicrobia group. Since classification is based on rRNA molecular phylogeny, this provides additional support for a role in rRNA metabolism. This small protein, about 50 amino acids in length, is rich in basic residues, a third line of support for rRNA interaction.	1.35289e-19
NZ_LM997411.1\|WP_009062064.1\|251334_253257_-\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NZ_LM997411.1\|WP_009062055.1\|256550_257444_+\|ChaN-family-lipoprotein	gnl\|CDD\|377239	pfam04187, Cofac_haem_bdg, Haem-binding uptake, Tiki superfamily, ChaN. This is a family of putative bacterial lipoproteins necessary for the uptake of haem-iron. The structure of UniProtKB:Q0PBW2, Structure 2g5g, comprises a large parallel beta-sheet with flanking alpha-helices and a smaller domain consisting of alpha-helices. Two cofacial haem groups (~3.5 Angstom apart with an inter-iron distance of 4.4 Angstrom) bind in a pocket formed by a dimer of two ChaN monomers.	6.486e-59
NZ_LM997411.1\|WP_009062043.1\|261576_262935_-\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl\|CDD\|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	2.74652e-40
NZ_LM997411.1\|WP_009062039.1\|263294_264062_-\|type-I-U-CRISPR-associated-protein-Cas7	gnl\|CDD\|187869	cd09738, Csb1_I-U, CRISPR/Cas system-associated protein Csb1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; Contains several motifs similar to Cas7 family; also known as GSU0053 family.	1.20061e-33

>NZ_LM997411.1|WP_009062048.1|260468_260837_+|hypothetical-protein
MVFVKLEETEGQSSAPSGAYREWSSKFFEESFQNHQQSPRGGAYRGFADQKHNPVSQVEERKSRKERAGEEPDEQIDPGPRVAYNLVQQSVPSEEVWATEHLLLKLIPNAFTVKLEDVANVV
>NZ_LM997411.1|WP_045086442.1|258772_260392_+|IS1634-family-transposase
MYLQEVRTRHKGKIYRSYIVRESYRVGKQVKTRRIANVTRLPEEAREVLAAALQKKRLVPVEGLEVQEALDYGGLAVLEEAWGRFGLDEVFARVGSERKRRLLKAMIFGRILFPSSKLVLREEARGTLLAKACGLEEKDLDEDELYRAMDELNGCWSGIEKKLYQGSQPQGASLVLYDLSSVYFEGEGPEGLAQYGYSRDHRQDRRQVLLAVATDGRGIPFHVEVLRGNRADRTTLTGLLVTLRRRFGIQEATFVFNGGMRSCWNLEILTGMELEYVTRSTRAKLQEILSRLPEDRQLWLTDRTRVLEIEQEGVRYVIAGGEWRAQRDRERRQSRIAQAEEVLRQITKAARRQVNPVNLGSRVGRALQRLQAHKYFQYGVDASGRFWWKLDQERVKEEEATDGWYLLETNLPATKASGQAVLTHYKQLAVVEAAFSELKSYLEVRPVYHWRPDRVRNHVRICFLAFWMSARLGVEWMAKGFTEEVPKVLRRLQTIRLVKLSLKGQPLIGLFSQIPPELNALLQKIDLLSLFASPPKWAM
>NZ_LM997411.1|WP_045086441.1|258326_258605_+|hypothetical-protein
MTRRDGMACRMFTSPKSGGGKKFCQSRTIEGTFGKLWNMTEWVLIVLFPDGDRRAEAFLPINVGCGERAGNGTFFCVVGRLVCLGTGMVPAG
>NZ_LM997411.1|WP_009062055.1|256550_257444_+|ChaN-family-lipoprotein
MKKILIILFILFLSFYRIGNAAEGIWIDLKSGAIVSQKELLEDLSKARIIYLGEVHTLHSHHKAQFELLKLLYNRHIPLALALESLEAKDQKIIDQFINGQLSFKQFSEAIQWKKKWPNYLDYKPLCLFAQKHHIPLIGIDTPHSIVSNVARKGYNSITKKEKAEFPLATITPLYRRFLTPYLSVHAFMDKKRIALAIEAQRLRESSMAKHILSFLNSPLGSQRTICVVTGEIHVRYGLGIPQLTQPFAQRILLFGSKEPLHLSKREKQISKQLVLDHQSFSFIPSTVADYFEVLAF
>NZ_LM997411.1|WP_009062057.1|255825_256515_+|HAD-family-phosphatase
MKKDHDTYQWAALFDWDGVIVDSVKQHEQSWRMLAAEQHKEVEQDFMNKTFGMKNEKIISEFLGWTQNPEEIMQLSKRKEELYKKIVQEEGLCLIDGLKEFLDCLKQKHIPMAICSSTTKTNIFFVLEKLGIKEYFSVIVGAEDVREGKPHPAPYLVTAKKLGYVPSCCVVFEDAPAGVESAKKAGMKVIALTTTRPKNNLENADLVISSWKELSLETIDVLFNAVSQQ
>NZ_LM997411.1|WP_045086438.1|254538_255840_-|hypothetical-protein
MVFFHIKLPGLKAYRSKRSILHAKNNKKELYRPNSNTFSRKVLFSWKVMTKVGIVILLFKISFSQNSFCKNLRVNQEQYKSLASKKELLKAYKARGFLALYRNRNSEARKFFQMCYSLSPEDAKLCELLAIASLRENDRRGVIFWMYQAHLNDLARFYLTIKQPFECSNPFQNATCPMLSTSYPVVPIEIDGHFFAFLIDTGASTSIVDKQVAEALGLKERGASELVLSNGERIQGALSTLPILRIGSLAIKNVPVILIEKLKPLSFDAKNCFHGVLGTDLLSRFNILIDYQTKKIVISKKAMELEAAFLSGSKLLAEIPFLFSPQGLLLVKGSMQSKEIFFIYDTGSGGYPLEFNQKYRNIFFGFSGTARSSLRFGPVAIKKISETFTQLPSDLEEREEIPIGGIIGNRLFSRYKVLLNFQKMVLQLYDQKN
>NZ_LM997411.1|WP_009062062.1|253507_254329_-|GTP-cyclohydrolase-I-FolE2
MPNVSTLMKNSLSASLADCQSQQDHRKIKIHRVGVKGLRYPIEVRDKNFESQHTVATVSLLVDLPHHFKGTHMSRFVEVLNAHGRMVHVCNVFSIVHELQKKLHAETAHVIMEFPYFIEKNAPVTGSKGLVDYQVRFEAAAYLDETDFVMWVTVPVTTLCPCSKAISDRGAHNQRGYVSVAIRFVQTIWIEDIIELVEASASSPIYSLLKRPDEKYVTELAFDNPVFVEDLVRNVALRLNANQDILWYRVEAENMESIHNHAAYACVEKELET
>NZ_LM997411.1|WP_009062064.1|251334_253257_-|phosphomethylpyrimidine-synthase-ThiC
MAQNSSRLTYLDIVSKGKELSSFLLSFFPNSKKVYIQGENRGVNVPFRQIKVAHNGSGEATDHSFFYAYDTSGPYTDPFAGVEIGSGLFPLRAEWIEQRGDCEPYEGRPIKPEDNGWVSVKDKAAILLKNGAQKLPLLKKRLPLRAKAGRRVTQLHYAKKGIITPEMEFVAIRENLGRKGSSLRQGKGPLYSQHSGLAWGASLPEEITPEFVRKEVASGRAIIPSNINHPELEPMIIGRNFRVKINANIGNSAISSSMDEEVAKLVWAILWGADTVMDLSTGKNIHEIRELIIRSSPVPIGTVPIYQALEKVGGIPEELSWEIYRDTLIEQAEQGVDYFTIHAGVLLRYIPYTANRLCGIVSRGGSIMAKWCLAHHQENFLYTHFDEICEILRSYDISVSLGDGLRPGAIADANDAAQLSELFTLGELTKKAWEHDVQVMIEGPGHIPMQLIKENMDLELKHCFEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGCAMLCYVTPKEHLGLPNLEDVKTGVIAYKIAAHAADLAKGFPGAQLQDNFLSYARFHFQWEDQFNLSLDPPTARLFHDENLPQPAAKHAHFCSMCGPKFCSMKITEEVLKYAEKNKLTTDDAFLEGMKEKAEEFRKIKNIYI
>NZ_LM997411.1|WP_009062066.1|248472_251241_-|2-oxoglutarate-dehydrogenase-E1-component
MRQKPSLSASSMVMSNRKSIGIENLALLEEYYQRWKKDPASVSADWSAFFEGFEFGYESLKNGQLGKKVERRAIADDLKKQRAVYELIHAYRTLGHYIANLDPLGFNQYEYDELKLERFGLNQKDLESYFDSGDLAGGGRKTLREILEILKKSYCSTLAVEFMHMDSFVQRKWISQRIEGKSFYAGFSKEHKKQILYDLLKAELFEAFLHTRYVGQKRFSLEGSCTLIPMMDALIEACPAHGIDRLVVGMAHRGRLNFVANVLQQDYKVIFDEFSENYIPEGVLGNGDVRYHLGFEAALKTKSGSIVTVGLTPNPSHLEAVNPVVEGKARAWERRLKDTEQRKKVLPLLIHGDASFMGQGVVQETLNLSRLEGYTTGGTLHIIVNNQIGFTTVPQDGRSTHHCTAVALMLGVPIFHVNSDDPLAAVFAVLLALEYRQVFGQDVVVDLVGYRKYGHNEGDEPSFTQPLLYKAIAQHPNISDVFLDQLIKSGEMTREEANEYRKIFVAELNQKMEESKEWIKQENPPTLRPRLACPRIFDPVKTAVPLEEFLYVGHALVREPPDFNLNPKIRKILEERKAMVEGKQPILLAFAETMAFGTLLYEGIPVRLSGQDSRRGTFSQRHAVLYDTKVSKKYVPLANIHPNQAIFCIYNSPLSEYAVLGFDYGYSLDYPEALIIWEAQYGDFANGAQVIIDLYLVSSESKWGVTSNIVLLLPHGYEGQGPEHSSARVERFLQACAEDNIVVANCTTPANYFHILRRQVLRGFSKPLILFTHKSLLRNPQCASSIPEFVQGAFEEVLADPQVNQPSSKVILCTGKVYYDLIDYRSRIGRMDIPIVRIEQLYPLHEKKLKEIVLRYQPQSLVWCQEEPKNMGAWSYMFPKLNDMFSLPVLYAGREASASTATGSMAYHRLEQQKLLSDAFGR
>NZ_LM997411.1|WP_009062068.1|247252_248431_-|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase
MDIKMPSVGESIESGLIGKWLKKEGERVQSGDALCEIETEKITTEIYAEKEGILHILVKEGSEVKVGQTIAQLEELPSGKMEQEPSASIKEEEEKEEKTVLEPQKELIEPVKKEEEEEKASVEAPLRRPGRITKEEALQLMEEEKEEKEEAKEVEAFALGPQEKRKPLSPIRKKIAQRLLEAHIGTAHLTTFNEVDMSTVLELRKNYGKRFEEKYGVKLGLMSFFVRAVVEALKKIPEVGARIEEDELVYPSTLDLGIAVATEKGLIVPVIRSAENLSFAQIEKTIQELAIKARGGKITLEDIEGGVFTITNGGVFGSMLSTPILNPPQSGILGMHAIKERPVAINGKVEIRPVMYLALTYDHRVIDGKEAVSFLVLVKEFIEQPASVLLEV
>NZ_LM997411.1|WP_009062043.1|261576_262935_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MMASGSHTETKTLCISVNFIHGCYNGIEWPPSPAKFFCALVAGNRTGCRKLEWGEEEKAAIRWLERLDPPEILVPPYRIGTPYIQYGVNNDEKQGKVEKWKYPHRIQEPLHFLWRFPSGEEEMARIICRMSRRIIALGHGSDSVWVSGKILEDDARPPGDAYKPAMRGERIKVPFPGYYDLLERRWRNGISNVRSSPSEERYVLYSWSNPKPWKWRVFLLTSPTSGTILSFPWSSASIIAAWVRHAAGEALGKLRDPAWIKRVVMGHCEISEIRHRWAYVPLPSVHPKHGDGLIRHVAVLVPDNENTDIVDVLDGCCLTNTGGEMMAVLEAEHKLSPMYGGKSKVWRTVTPVVFPGHWQRRGRNREGRLHTMLAAMLSEAGIEENSVEQCQVRREPFFKGCELAQQAKAPQHLLALPRMHLELVLKEEVQGPMLLGLGRFAGLGCLAGVNVL
>NZ_LM997411.1|WP_045086443.1|262954_263161_-|hypothetical-protein
MTEQAREPIVVPSTEALVEWTKRYLPSQPLKEETFVFETEMAKQFVEKSNEKKKKKADESTALEELNI
>NZ_LM997411.1|WP_009062039.1|263294_264062_-|type-I-U-CRISPR-associated-protein-Cas7
MNASNVRNVSVEEMENWITDENVIAVVVEEQLEPAGGWRFPVKPPTFGALDEEETTPPYCIDELPDGHNVCILDTPASANNRREPIFLREEFKDLVPKIQIIINEKKKSLLELPHRAADVMIKCSKGHSKIAEALSKYLNGNAWPLAEIAPTTLVFGAWDSRGENSNLKISGVLRSCTLAYDVKPIHMPFQYVPPVDYKSEIFGADKPQKKLSEMGFDGALGVGWGGRNDWWWNMHANRSKPLRFAGIWHSRGRR
>NZ_LM997411.1|WP_009062038.1|264074_264854_-|hypothetical-protein
MNMEKSIVGIDPNNPGHAWACCGLAELCGRIEPESLFRFELDEKDSRFVTNGPLDEALRRLLSDETRVQRVAKKNEKRKKEESGENEDESKDDPILLHIPGLEPLRLDWWLKWSEKGELKPFAPMKLWAGQRDGLEIFNGILRECRSQRNENWLKWKGDNPALGVDPSIAWTTRSTGHSIVPHGNKPGIELLASIGLLWSKLSTSYQDWRGRYMLWTRPLPLPSARLAMVRLLEVEGKRYWHEIEWRGSNKNWKYAREE
>NZ_LM997411.1|WP_009062036.1|264850_267346_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3
MKDFTSQFCHLTGHEPYYWQIRLYEKLVTGEWEGLRRIVLPTGTGKTSLIPCYLLALANSPIRLPRRLVWIVNRRVVVDQASDDARCLTEKLDKPELEEVRRQLVMLSGGRWPKQPVAVSTLRGQLADNREWYLDPSRPAIIVGTVDMLGSRLIFRGYGCGPWRRAHHAGLLGFDSLIVLDEAHLEPAFDALLDTIETLRTESEICGLAPSHWIRMSATQRNSENAFRLEEDDKQDPVLSKKLKRAKRLTFVKAKSNLAAELKDQAIKLGKKYPGSRIVVFAKSPEDAAKAAKLIRKESKCEVSLLTGEIRGWERDRMTDSDTNYRRFTRPDRHEIGSSAYLVATSAGEVGADLYADHGVCDATTAESMLQRFGRIGRSGVDEEALIVIVISTKDEKDERISKTLEYLQDTIACNACLERIAQTPPPDETFREPPSLLILDRIILDALAATSVQLPKRLINLDEYLHGIEPERAPECHVAWRADVPLLAEASPEKIEEILDFYPVEPRELLRTTVDRLRKAIGGAKPELKCIVQYLVGAVEVMNIADLLRTNLRGAMILLPVEAGGFDEEIGCLVYDGGDKTSNAILDVADNDESEKRRRYLIQEDSDGFFVSIRLGQEEKVGADSLEEFYRKIGAARAKRKVVRLSPEDDVSQQLLAYIVWADKTDASEKNGATTILLSEHQDRVAKECERVAKALGLDDALIEMMQRCGLRHDDGKKDERWQKAAGNSSEKSVAKFLTQHGKLPFGFRHELYSVSDAMSDLEAHIIAAHHGWSRPNFPSAAVEFNPKRAAEADARFARLQSKYGHWGLAYLESILRAADALVSMEEQQA
>NZ_LM997411.1|WP_045086445.1|267961_268336_+|hypothetical-protein
MTFQKKRKRTINPIDAEPYGHESIFPFPYFEGWEPDVYPALSMYRELPQPRNVVLLGLRSSIRCWYQRRKDYFTIYPNLPQRVGKTHDFFLVRVEVLKADHRVFINFGTALAPSLLEVCSGFRA
>NZ_LM997411.1|WP_009062029.1|268556_268898_+|hypothetical-protein
MFLLAKTDGLSTIQTETDWTTARFLALADRWSEECRHLSSIRDMVLHPAYQQIIGMGPSMLLYILDELERHPDHWFWALRAITGGNSIRSDNQGRVREMTLDWLEWAVQRRLR
>NZ_LM997411.1|WP_079199499.1|269945_270098_-|small-basic-protein
MSQHRSYRSGSMLAAKRNVLKRYERINILKKQGKWKEGDRVLGLPKTKPV
>NZ_LM997411.1|WP_009062024.1|270415_271180_-|Zn-finger-protein
MQPSSSKQLDSKTQLIRCPACGHSQVESRWALSTICKKCFHYIGLATKKNSVPFFPSVPSKTREITCPYCQNSQKIYAQALSVGCAFCGAYLYVENLCLKGKIKRKISTLGDIDFEAGSEYAGATVQGRKIRIRGIMQCSFKATEEVEFCSQSVVKGIVVAPRVIVNRFASAKVKEVIAYELTVKGQLECETIIARDFLKIESFGMITTKKMLTNRLVAELFSRLEADFETYSLLARDIQKNGIELGEERLFLT
>NZ_LM997411.1|WP_009062022.1|271179_271422_-|polymer-forming-cytoskeletal-protein
MQNKDEVTILSPCISLEGELWVRDKAIVNCHIQGKIRVGGKLEILSEAVIEGEVYAQAIEIDSGAIINGRIVIGKNKQNS

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Crispr_ID: NZ_LM997411_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LM997411_2

2369605-2371835

TypeIII

Consensus_repeat	Method
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	PILER-CR
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CRISPRCasFinder
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CRT

29 spacers

cas2,cas1,csx1,csx3,cmr1gr7,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5

The CRISPR arrays of NZ_LM997411_2

>merge|NZ_LM997411|2|2369605-2371835|PILER-CR,CRISPRCasFinder,CRT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTTCTTTTTCGGCTTTCAGTTGATGAAGCCTTCCTTTAAGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACCCCGTAAATCACCCCACCTTTTGTTAGCATATGAGCTCTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAATTTATCCCACTCATACTTCAGAGTAACTTCTTCTTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTGCCCATGATCTCATATGATATGTTATTGAAATAATACTTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACCTTCTAATCTTGATTGCTGACCGTTTTCCCCGCTTAAGGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAAGTTCAAAGTAAATCCCATCCAATTTTCGATAGATAGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACCAAGCCCTGAGGGTGAAGACTTTTTCCTGATAAAGTCGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACCTGCTATTTCACCTTCACCTTCTAACTTGAACCGCTTCTCGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACCCTCATCTAAAGCTCCCCATTCACGATACATAGCGTTAAGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTCAAGTCCCAGTCTCTTTTCGTCATATATCCTCCCTTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACATTCCTTTTCAAGTTTGCCTTTATTCTTCTCACTCACTCGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACATGTTGTTATGATAATATTTCATGGGGATTTTGTGTTCCCGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTTTCTCATCTTCTGGCCACTTCCATAAGTTTTTCCGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACACCTTCTCTTCCTTTAATAGTCGAATATAAGCCATTAGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTTAAATGTTTGGTACAGCAGGAGAAACTTCCTGCTGTAGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAACTCATTCCAGTTTTGGAACTCTGGCTTACCCTCTGGTAGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTTTCCTTTGTTACAGGGTCAAAATTCGACCACTGGCGAAGAAGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAAATAAATGCCAATACATATCCTCCCCTAAGGGAAGATATGGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTCGATTAATTCTTTCAACAAAGACTCCCAATTGTGGTCTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAAAACCAAATATTTCGACCTGCTATATTCCGGATACTCGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAGATAAACTTCTTGGCTCTAGGGGATTGAACCCTAAAGGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACATACCAGCGAGCATTTCTGGCCCGATAAGCATGACTTCTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAGACCATACACTATCACTTCCTCGTCAGAGTAGTTGACTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTTCAGGAGTGAGGTAGTATCTCTTCATATCCTCATCCCAAGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAATGTCTCGAATCATCTTAATTTCCCAGTCTGTTAACATGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACACCAAGAAGCTTCAGGCAAGGGGAATACATATAAAATGTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACAAAACTCAACCCCAATAGACTTCTTCAATGCTTCCTGGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACTACAATAAAGATAAAGGAGGTAAAAATGAGGGAAGATTGTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGACCCAGGAACTGGGGGCTCGTCACAATATTTTGGTAACTCATAGTCGGAATAATGGATGAAGCCGAAAGATGATTGAGAC

>NZ_LM997411|2|2|2369605-2371835|PILER-CR
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTCTTTTTCGGCTTTCAGTTGATGAAGCCTTCCTTTAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCCGTAAATCACCCCACCTTTTGTTAGCATATGAGCTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AATTTATCCCACTCATACTTCAGAGTAACTTCTTCTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TGCCCATGATCTCATATGATATGTTATTGAAATAATACTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CTTCTAATCTTGATTGCTGACCGTTTTCCCCGCTTAAG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAGTTCAAAGTAAATCCCATCCAATTTTCGATAGATA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CAAGCCCTGAGGGTGAAGACTTTTTCCTGATAAAGTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CTGCTATTTCACCTTCACCTTCTAACTTGAACCGCTTCTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCTCATCTAAAGCTCCCCATTCACGATACATAGCGTTAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TCAAGTCCCAGTCTCTTTTCGTCATATATCCTCCCTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATTCCTTTTCAAGTTTGCCTTTATTCTTCTCACTCACTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATGTTGTTATGATAATATTTCATGGGGATTTTGTGTTCCC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTTCTCATCTTCTGGCCACTTCCATAAGTTTTTCC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ACCTTCTCTTCCTTTAATAGTCGAATATAAGCCATTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTAAATGTTTGGTACAGCAGGAGAAACTTCCTGCTGTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AACTCATTCCAGTTTTGGAACTCTGGCTTACCCTCTGGTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTTCCTTTGTTACAGGGTCAAAATTCGACCACTGGCGAAGAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAATAAATGCCAATACATATCCTCCCCTAAGGGAAGATATG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TCGATTAATTCTTTCAACAAAGACTCCCAATTGTGGTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAAACCAAATATTTCGACCTGCTATATTCCGGATACTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AGATAAACTTCTTGGCTCTAGGGGATTGAACCCTAAAG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATACCAGCGAGCATTTCTGGCCCGATAAGCATGACTTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AGACCATACACTATCACTTCCTCGTCAGAGTAGTTGACT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTCAGGAGTGAGGTAGTATCTCTTCATATCCTCATCCCAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AATGTCTCGAATCATCTTAATTTCCCAGTCTGTTAACAT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ACCAAGAAGCTTCAGGCAAGGGGAATACATATAAAATGT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAAACTCAACCCCAATAGACTTCTTCAATGCTTCCTG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TACAATAAAGATAAAGGAGGTAAAAATGAGGGAAGATT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCAGGAACTGGGGGCTCGTCACAATATTTTGGTAACTCATA
GTCGGAATAATGGATGAAGCCGAAAGATGATTGAGAC

>NZ_LM997411|2|2|2369605-2371835|CRISPRCasFinder
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTCTTTTTCGGCTTTCAGTTGATGAAGCCTTCCTTTAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCCGTAAATCACCCCACCTTTTGTTAGCATATGAGCTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AATTTATCCCACTCATACTTCAGAGTAACTTCTTCTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TGCCCATGATCTCATATGATATGTTATTGAAATAATACTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CTTCTAATCTTGATTGCTGACCGTTTTCCCCGCTTAAG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAGTTCAAAGTAAATCCCATCCAATTTTCGATAGATA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CAAGCCCTGAGGGTGAAGACTTTTTCCTGATAAAGTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CTGCTATTTCACCTTCACCTTCTAACTTGAACCGCTTCTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCTCATCTAAAGCTCCCCATTCACGATACATAGCGTTAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TCAAGTCCCAGTCTCTTTTCGTCATATATCCTCCCTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATTCCTTTTCAAGTTTGCCTTTATTCTTCTCACTCACTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATGTTGTTATGATAATATTTCATGGGGATTTTGTGTTCCC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTTCTCATCTTCTGGCCACTTCCATAAGTTTTTCC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ACCTTCTCTTCCTTTAATAGTCGAATATAAGCCATTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTAAATGTTTGGTACAGCAGGAGAAACTTCCTGCTGTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AACTCATTCCAGTTTTGGAACTCTGGCTTACCCTCTGGTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTTCCTTTGTTACAGGGTCAAAATTCGACCACTGGCGAAGAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAATAAATGCCAATACATATCCTCCCCTAAGGGAAGATATG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TCGATTAATTCTTTCAACAAAGACTCCCAATTGTGGTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAAACCAAATATTTCGACCTGCTATATTCCGGATACTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AGATAAACTTCTTGGCTCTAGGGGATTGAACCCTAAAG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATACCAGCGAGCATTTCTGGCCCGATAAGCATGACTTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AGACCATACACTATCACTTCCTCGTCAGAGTAGTTGACT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTCAGGAGTGAGGTAGTATCTCTTCATATCCTCATCCCAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AATGTCTCGAATCATCTTAATTTCCCAGTCTGTTAACAT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ACCAAGAAGCTTCAGGCAAGGGGAATACATATAAAATGT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAAACTCAACCCCAATAGACTTCTTCAATGCTTCCTG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TACAATAAAGATAAAGGAGGTAAAAATGAGGGAAGATT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCAGGAACTGGGGGCTCGTCACAATATTTTGGTAACTCATA
GTCGGAATAATGGATGAAGCCGAAAGATGATTGAGAC

>NZ_LM997411|2|2|2369605-2371835|CRT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTCTTTTTCGGCTTTCAGTTGATGAAGCCTTCCTTTAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCCGTAAATCACCCCACCTTTTGTTAGCATATGAGCTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AATTTATCCCACTCATACTTCAGAGTAACTTCTTCTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TGCCCATGATCTCATATGATATGTTATTGAAATAATACTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CTTCTAATCTTGATTGCTGACCGTTTTCCCCGCTTAAG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAGTTCAAAGTAAATCCCATCCAATTTTCGATAGATA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CAAGCCCTGAGGGTGAAGACTTTTTCCTGATAAAGTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CTGCTATTTCACCTTCACCTTCTAACTTGAACCGCTTCTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCTCATCTAAAGCTCCCCATTCACGATACATAGCGTTAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TCAAGTCCCAGTCTCTTTTCGTCATATATCCTCCCTT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATTCCTTTTCAAGTTTGCCTTTATTCTTCTCACTCACTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATGTTGTTATGATAATATTTCATGGGGATTTTGTGTTCCC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTTCTCATCTTCTGGCCACTTCCATAAGTTTTTCC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ACCTTCTCTTCCTTTAATAGTCGAATATAAGCCATTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTAAATGTTTGGTACAGCAGGAGAAACTTCCTGCTGTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AACTCATTCCAGTTTTGGAACTCTGGCTTACCCTCTGGTA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTTCCTTTGTTACAGGGTCAAAATTCGACCACTGGCGAAGAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAATAAATGCCAATACATATCCTCCCCTAAGGGAAGATATG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TCGATTAATTCTTTCAACAAAGACTCCCAATTGTGGTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAAACCAAATATTTCGACCTGCTATATTCCGGATACTC
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AGATAAACTTCTTGGCTCTAGGGGATTGAACCCTAAAG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ATACCAGCGAGCATTTCTGGCCCGATAAGCATGACTTCT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AGACCATACACTATCACTTCCTCGTCAGAGTAGTTGACT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TTCAGGAGTGAGGTAGTATCTCTTCATATCCTCATCCCAA
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AATGTCTCGAATCATCTTAATTTCCCAGTCTGTTAACAT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	ACCAAGAAGCTTCAGGCAAGGGGAATACATATAAAATGT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	AAAACTCAACCCCAATAGACTTCTTCAATGCTTCCTG
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	TACAATAAAGATAAAGGAGGTAAAAATGAGGGAAGATT
GTCGGAATAATGGATGAAGCCGAAAGGCAATTGAGAC	CCAGGAACTGGGGGCTCGTCACAATATTTTGGTAACTCATA
GTCGGAATAATGGATGAAGCCGAAAGATGATTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LM997411.1\|WP_009060306.1\|2373216_2374866_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227708
NZ_LM997411.1\|WP_079199481.1\|2362249_2363671_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	cd09661_cmr6gr7_CAS-III-B	gnl\|CDD\|213662
NZ_LM997411.1\|WP_009060288.1\|2366673_2367786_+\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|187817
NZ_LM997411.1\|WP_009060308.1\|2375002_2375533_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379276
NZ_LM997411.1\|WP_009060278.1\|2360937_2361888_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|274210
NZ_LM997411.1\|WP_009060280.1\|2361880_2362246_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NZ_LM997411.1\|WP_009060318.1\|2378117_2379023_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
NZ_LM997411.1\|WP_009060321.1\|2379916_2380588_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl\|CDD\|153219
NZ_LM997411.1\|WP_009060316.1\|2377366_2378110_-\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
NZ_LM997411.1\|WP_009060276.1\|2359541_2360840_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NZ_LM997411.1\|WP_009060292.1\|2368927_2369305_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_LM997411.1\|WP_009060309.1\|2375587_2375959_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LM997411.1\|WP_009060290.1\|2367914_2368922_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NZ_LM997411.1\|WP_045086745.1\|2371929_2372166_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LM997411.1\|WP_009060323.1\|2380595_2381315_+\|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	unknown	unknown	gnl\|CDD\|240083
NZ_LM997411.1\|WP_009060283.1\|2363710_2364190_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	cd09657_cmr1gr7_CAS-III-C	gnl\|CDD\|273859
NZ_LM997411.1\|WP_009060285.1\|2364493_2365726_+\|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	gnl\|CDD\|378186
NZ_LM997411.1\|WP_009060315.1\|2376637_2377348_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225136
NZ_LM997411.1\|WP_009060319.1\|2379036_2379858_-\|diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|234768
NZ_LM997411.1\|WP_009060287.1\|2365718_2366672_+\|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	gnl\|CDD\|370583

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_LM997411.1\|WP_009060280.1\|2361880_2362246_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	3.3e-16	54.5	0.8
NZ_LM997411.1\|WP_009060276.1\|2359541_2360840_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	4e-62	205.6	0.1
NZ_LM997411.1\|WP_009060292.1\|2368927_2369305_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	1.5e-25	84.1	0.3
NZ_LM997411.1\|WP_079199481.1\|2362249_2363671_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	cd09661_cmr6gr7_CAS-III-B	2.8e-32	106.8	2.2
NZ_LM997411.1\|WP_009060290.1\|2367914_2368922_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	1.2e-88	292.0	0.0
NZ_LM997411.1\|WP_009060288.1\|2366673_2367786_+\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	9.1e-59	193.6	0.0
NZ_LM997411.1\|WP_009060283.1\|2363710_2364190_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	cd09657_cmr1gr7_CAS-III-C	8.4e-12	40.2	0.4
NZ_LM997411.1\|WP_009060278.1\|2360937_2361888_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	5.2e-58	191.6	0.0
NZ_LM997411.1\|WP_009060285.1\|2364493_2365726_+\|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	1.6e-75	249.3	11.7
NZ_LM997411.1\|WP_009060287.1\|2365718_2366672_+\|CRISPR-associated-protein-Csx3	csx3	mkCas0115_csx3_CAS-I:CAS-III	1.4e-98	324.1	0.0

Protein	Function_ID	Function_description	E-value
NZ_LM997411.1\|WP_009060306.1\|2373216_2374866_+\|hypothetical-protein	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	5.19472e-09
NZ_LM997411.1\|WP_079199481.1\|2362249_2363671_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	2.49815e-18
NZ_LM997411.1\|WP_009060288.1\|2366673_2367786_+\|TIGR02584-family-CRISPR-associated-protein	gnl\|CDD\|187817	cd09686, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	2.5427e-55
NZ_LM997411.1\|WP_009060308.1\|2375002_2375533_+\|hypothetical-protein	gnl\|CDD\|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	0.00165457
NZ_LM997411.1\|WP_009060278.1\|2360937_2361888_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	3.13594e-52
NZ_LM997411.1\|WP_009060280.1\|2361880_2362246_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	8.19942e-16
NZ_LM997411.1\|WP_009060318.1\|2378117_2379023_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	4.1672e-159
NZ_LM997411.1\|WP_009060321.1\|2379916_2380588_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl\|CDD\|153219	cd01748, GATase1_IGP_Synthase, Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS). Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS). IGPS incorporates ammonia derived from glutamine into N1-[(5'-phosphoribulosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide (PRFAR) to form 5'-(5-aminoimidazole-4-carboxamide) ribonucleotide (AICAR) and imidazole glycerol phosphate (IGP). The glutamine amidotransferase domain generates the ammonia nucleophile which is channeled from the glutaminase active site to the PRFAR active site. IGPS belong to the triad family of amidotransferases having a conserved Cys-His-Glu catalytic triad in the glutaminase active site.	1.57263e-92
NZ_LM997411.1\|WP_009060316.1\|2377366_2378110_-\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	2.854e-85
NZ_LM997411.1\|WP_009060276.1\|2359541_2360840_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	1.22092e-52
NZ_LM997411.1\|WP_009060292.1\|2368927_2369305_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.99578e-24
NZ_LM997411.1\|WP_009060290.1\|2367914_2368922_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	8.83608e-102
NZ_LM997411.1\|WP_009060323.1\|2380595_2381315_+\|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	gnl\|CDD\|240083	cd04732, HisA, HisA. Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-ribosyl)-4-imidazolecarboxamide). In bacteria and archaea, ProFAR isomerase is encoded by the HisA gene.	9.47494e-92
NZ_LM997411.1\|WP_009060283.1\|2363710_2364190_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|273859	TIGR01894, hypothetical_protein, CRISPR type III-B/RAMP module RAMP protein Cmr1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents the region of stongest conservation, the N-terminal half, of one such family, represented by TM1795 from Thermotoga maritima. This protein is the first of a set of six genes, mostly from the RAMP superfamily, that we designated the CRISPR-associated RAMP module.	3.49008e-07
NZ_LM997411.1\|WP_009060285.1\|2364493_2365726_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	2.1038e-59
NZ_LM997411.1\|WP_009060315.1\|2376637_2377348_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	3.42223e-18
NZ_LM997411.1\|WP_009060319.1\|2379036_2379858_-\|diaminopimelate-epimerase	gnl\|CDD\|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	2.65703e-93
NZ_LM997411.1\|WP_009060287.1\|2365718_2366672_+\|CRISPR-associated-protein-Csx3	gnl\|CDD\|370583	pfam09620, Cas_csx3, CRISPR-associated protein (Cas_csx3). This entry is encoded in CRISPR-associated (cas) gene clusters, near CRISPR repeats, in the genomes of several different thermophiles: Archaeoglobus fulgidus (archaeal), Aquifex aeolicus (Aquificae), Dictyoglomus thermophilum (Dictyoglomi), and a thermophilic Synechococcus (Cyanobacteria). It is not yet assigned to a specific CRISPR/cas subtype (hence the x designation csx3).	1.93071e-22

>NZ_LM997411.1|WP_009060292.1|2368927_2369305_+|CRISPR-associated-endonuclease-Cas2
MEKTTEKMNEDPSYWWYEAFAPAPREKKPPGDNKMLTVIAYDVCDDRRLHKIAKICEDFGIRVQFSVFECYLEESELEELWQKLLAEIDPKEDRIVAYKIDARLAKEIRTAGTMVCSEKVICFLV
>NZ_LM997411.1|WP_009060290.1|2367914_2368922_+|CRISPR-associated-endonuclease-Cas1
MPSAYILQTYAKVSLCSERLQVVSYNKENGTEELIREIPLRELERLVLDQTVSITTPALCELLLRNIPISFIGFNGQILGGFFPPPNSHGLWRLKQYQNCLDPKSVLAYSKQLVKAKIYNQRRSLQRLSSNRKINNENDIEWLNHLLFKVASAATVDEIRGYEGASTARYFQCWATFLPQEFPFERRSNRPPLNPVNACISFGATLLYNEMTALIHLHGLDPALGFLHAPENERWSLALDLIEPFRPVIVEALALDLFSHKILNKEHFEKKNGGCYLNELGRKKFLAQYETRLERQFQSEFSGSRTTLRAQLEGCVCSFKAALEDPSKFEPFLMN
>NZ_LM997411.1|WP_009060288.1|2366673_2367786_+|TIGR02584-family-CRISPR-associated-protein
MNQNKEIILLAVIGISPAVITETLWALAEENPPIYPKYIDIVTTAIGKKVIEKELLEPRGKCLWEEFRNWLIKEKNIPKDSHILREIKVIVSPFLDQGKCLELEDIRNIKDNEETADYILEEVRKITENPDTQLIASVAGGRKTMGILLYSAVSMLGRKGDRITHVLVNEPYDDPRLQPKFYFPQQKEQILKTITGNIVYAKDAKIELADIPFVKFRELFPKEFGRLPGRFTDLVWQYSKEIKELYPQVGFDSQTGEMIVNEKKIKLKGKELLFFAFLWDRLEKNLPPLGCHKEVDKPFKVFAVEWKKKNQQLSHLFPEHSNFDEDDSKKCLSNLRKKLNDRGLNKFVDLIFPLRSGVGLSNSIKMKDNS
>NZ_LM997411.1|WP_009060287.1|2365718_2366672_+|CRISPR-associated-protein-Csx3
MNNLKLKIIDTPDFQILKISITGNGILEASILKNIELPKVNYAKGVILYGRAPIWIYGFFVHQFHPCRWIAIFDPRMGGIIIEAHHIEAPQLGYVIPIEVIQPHVESNQNLLQDTVQSTAQSKTSSPPSTLIIALVGPPHSGKSVFLMLLQESLKRILPISFYQEKTYTIRACPDGEGNWFHEAYPYSKTLRFKNQWNQSFVDNICQHIKEISKTKRLLFVDCGGKIDRFNHQILGLCNSALIVSRDDLLAAEWRGATQILGLNLLAQIQSVQENISTVISSSPILTVKLGKLERGINPEEVVLPEELIKKIQSLIS
>NZ_LM997411.1|WP_009060285.1|2364493_2365726_+|TIGR02221-family-CRISPR-associated-protein
MNLLQLSFLGTGNYRSTKYSFSQRRHHETKFFPLALALEKHPKTIFMALTKKIENGDNWKELKEEFKAKNFKYEIICIPEGKEEQELWDIFESIAKMIPKQSELIIDITHGYRSLPLIALSTIVYLRQVKEVNIKGIFYGAYEANKNDITPVFDLSIFLDLIEWLGASKRFIDLGDSSEFAKLLNKIQNELYQEKDKEEKKPTHLKNLGSSLKDLSLALNLSRVLEIPKICKRVEDILKNQELREEINKWAKPLDLVIDEVKETYKATAFDGLHGQIELAKKYLQHGYVMQCATLLREWIISYVCEVIQDDSNDPEKRKEVENILNNLGHKIRNNRPEDSLQSREDKENIKNKLSSLDPKLIEAWSRIIQVRNDLAHCGMGRKKEILANELKNQVEKALDSIEELLQNHE
>NZ_LM997411.1|WP_009060283.1|2363710_2364190_+|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MRKKAELSRKAEVRVPFIRGQLRWWLRLLGGFNCLSEDACKLESNIFGSAVSSSLASKPIIKALSVHRSKRKSKENLGAGKPKNRQAIEQDSKFKLQVRWKGAPSPFSSLNDALSNMHTLINIWIHLRALGAKSSKEFGAMTFTTVSSSLAIEEGSQFF
>NZ_LM997411.1|WP_079199481.1|2362249_2363671_+|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MSMNDNVAKKDKLLLINDVESVLNTISIESRSLLLEKYIDPRIKKDERKAQFSTAINIKNPNITKYRLQSIWNSLYSKLKDASLLFAQLQSRMMVNMAGGVLENAGLCLDRFGIPYIPGSAAKGCARRMAIEKLLEASEHEKIQLLSQIALVFGWSELDWKNENNSDFYYGCSNTPPLVDDVVDQAAGLVLEAMSIPTKTDDKLRNQLIKTVPNYAGTIRFLPAYPIPENFYPTEEKKLVGNELELDVITCHHQKYYSHETGWEDAWDKEDPIPVFFPAVSPYLIFCFCIHPSTRRANGKVKDFALEWLKNGLESFGIGAKTAAGYGWFKDCTNKVEEKLEKIRKEEEIRQKEQEEKRKKEEEEERRKIEKEKKQQKFEEATKGMSPEEKEAFKLHSEKNDQQFKDKLINDFLKSDANQQLVFYLCIKKHKPGVWEEINKAAQQSPKKEVRKKWANISQKLKEIAKNRKERLP
>NZ_LM997411.1|WP_009060280.1|2361880_2362246_+|type-III-B-CRISPR-module-associated-protein-Cmr5
MDNLEILRAKHALKKAEGLKKESVNRLPGLIVSNGLLATLAFVCEEKPEREPLKIAMDAVAEYLSKRNILKDIKENNNAAKEMLHQLITKGSSLDLQQATYETLKYLAYLKRFSEKKSSSS
>NZ_LM997411.1|WP_009060278.1|2360937_2361888_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MATSESAIIYLFTRTSLHVGSGGSVGAIDLPIIRERHTAFPIIPGSALKGVFADEWIEINENTYQSNDAEIKEHIYQRNTEGKDLFGTEEKGGMLQFSEAKLLLFPIRSPKGCFGWITCPLILKRYCRDTGQTILDSIQLSDNKALFKKESCLCINEGGKEKVILEEYIFEKTQEDSEEIIKAFVNQLPVDLVSIDPIWKEIGNRLVIVSDSMMSFFTQSACEIAQHVKINDKTGTAESGALFNQENVPSETAFYSIVRKGPSRNENSFKPIEVLEKKIKEKNYLFQFGADAGTGLGYCTTYLTKTTHKEGESNNG
>NZ_LM997411.1|WP_009060276.1|2359541_2360840_+|type-III-B-CRISPR-module-associated-protein-Cmr3
MTTFDLIPFDTCFFRDSKPLAAGSSYGRGARWPLPLTIHSAIRSALLSLSGLTPTEKKNGYERRGKSQGKIGTEAYNWLHIKGPFPVDRKEHRLFFPTPLDISWCIHQENNRSLKPSKLLRPLKQTEMFNLSECKSNLPNPLRYPVVSQDPPSKVRPPSFVSSEFYKYYLEDKLNEINSSECSGDKELWDSEYRIGIGINPETQTVEESKLFAAEHLRLREGIRLCFSINDPPFYKLQNPDESPIECLNQETITVGGEDRFFKVEKVKEPLLFPSLDVNDLKTTRLKWVLLSPAIFSQGWLPGWIDPQKQKENVLLRAIDKEKRRVFRKQRRSDREWKYDPSKDEAPPIKATLVAARIGKPIIIGGWEVLEKGPRPTLLAVPPGSVYYFETEKEEDTKSLFQALHERCRSDYYGEKGFGLGLCGTWDYFEFT
>NZ_LM997411.1|WP_045086745.1|2371929_2372166_-|hypothetical-protein
MMVLVFSLLTPIGRAGASGDLKSSKATSGCTRAFDIGARSRLSRLDYKAKPETCEQYAGRGCLGRARNLPNQDPQHRD
>NZ_LM997411.1|WP_009060306.1|2373216_2374866_+|hypothetical-protein
MIYNSHVGGNICINVLTKSNGIWEKECVMCLREVKSQQRSKDYKSYFIQESYRNKKGLRAQTIYNVAALSEEIQELMRLDLHRKRISEIEDLRLEEQSNFRDLAVLRETWDWWGLEDVLASVKDPNKTKHLQALIFGRILFLCSKLFLKEEAWGTLLEQACSLEKSEGFEEEGFYREWMGSAGVWSRIEHELFRRASHGRVRLVLYDLSSTYFDGEDPNRLARYGYSRDYQEEQPTVILSMATDAEGIAVHVEVHRDNRSDSTTIPKLLVTLWRRLGIAKAVFVFDCGTRSLLSLEVLMGMERGSVARATWAQFQELMDKLSLDRQPELWDRTKRMDVEKDGLWYIIAEREWLAKRYLERQEARIGKTKLLLEEFKRNARKGEDAFCLDSRVGRMLERCKAHKYIRYGIDRKVRFWWKLHEEESAKEEATDDRYLLETNLLPTEYSAKKVLAHYKNLCEANQAFCRRFPAYWMTARLVAEWSKRGVFKHVPRLLRRLQTIRPSLLSVKGKPAACLLIKISRKLNRLLEKTASLPAFLPAAGLGNPGDSS
>NZ_LM997411.1|WP_009060308.1|2375002_2375533_+|hypothetical-protein
MKRQIRIFLKRALLYAYRAMRRLCGLHVVPVHYYCPLPDPIELEKTQKSWMRPSKMRGVEVDLESQVKNFRQICLPFVGEYAGNAVYKYASSMGFGPGYGYIEAQALHAMVRYLKPRRIIEVGSGVSTFCMREAARRNEENGGERVEITAIEPNPSPALRAMAGIRLLAQRVQDTG
>NZ_LM997411.1|WP_009060309.1|2375587_2375959_+|hypothetical-protein
MVKAGGDVNFLILEVLPRLREGVVVHFHDIYFPYDYPRDLLKTFFPSTESSLLHAFLAFNHRFRIIFCMSLLHYKCPKVLTEVFPEYIPQGGQDGLVEERVAAFTTPPGHFPSSIYLRVGVSE
>NZ_LM997411.1|WP_009060315.1|2376637_2377348_+|methyltransferase-domain-containing-protein
MNSLFLRAFCVLLCFLFYGFFQAGYATTSIREQDEYRFKEPALWAEQFDAPSRDKWQKPQAVIQALQLKPGQTVADIGAGTGYFAIKFARVVGPQGRVIALDRESSMVRYLKKRAKKESLNNLIVRKSPKNNPGLEKQSVDLIFFCNSYHHIHNPNYLKALAKALKKNGKVAVIDIKPNAPRLFPATARFKRHIKLSAQAVVADFKQAGFSLDKEFGFLPYQYFLEFKPTSIASSK
>NZ_LM997411.1|WP_009060316.1|2377366_2378110_-|4-hydroxy-tetrahydrodipicolinate-reductase
MNRQGRITRILLTGAQGKMGQTVVQAAALDPEVKIVGLIDKEDRLEEAFKIAADCIIDFSVHHFSQELVEAALSHSLPLVIGTTGHTPEELERIKEASQKIPIVMSPNFSLGVNLLELMVHTATVVLGKSYDKAIIDIHHNTKLDAPSGTAKRLLEVLMAAEKIIEEASKDFSSQEKLPQVHSIRAGTVVGVHTVLYCGPGEVIELTHRAENRFPFAHGSLKAAKWIVGKPPAIYSMRDVLGLGQLL
>NZ_LM997411.1|WP_009060318.1|2378117_2379023_-|4-hydroxy-tetrahydrodipicolinate-synthase
MKIQGTYTAIISPFHNGQIDRKALERLLEHQIENRIDGIVPVGTTGESPTLSYEEHIELVRLTAEIVEKRIKIFAGTGSNSTAEAIHLTKEAEKIGVDGVLLVSPYYNRPSQEGLFRHFSAIAASTSLPILLYNIPSRCGVDIAVDTVKRLVEKNKNIVGIKEAGGSVDRVSQLVEALPGEFSILSGDDALTLPFLSVGAVGVVSVASNLFPRPVSALVRLYLEGKPFEARQLHQTLYPLFRDLMIETNPVPVKTALAMEGLTDLELRLPLAPLQPQNLEKLKTTLSRTKEKLAKVEHLWA
>NZ_LM997411.1|WP_009060319.1|2379036_2379858_-|diaminopimelate-epimerase
MTLFFTKMNGAGNDFILLDNRQGLLSLDASSIAYLCDRHRGIGADGILLVEWAEKEGLRMVYFNADGSRASFCGNGARCFARFAWETEHKNVGCGRLSFLTDCGTVEAWVEGERVKITMPSAKNLRLDVPISLSDRTLNGHAIDTGVPHVVLFGDYEKWTEAALQDLGYEIRWHKAFQPEGTNVNFVWKAGEQAIKVRTYERGVEGETLACGSGVTASALISSVILGMEPPIDVYVRSGERLQVHFRRTEKGFEEVFLEGPAKKVFVGQIELP
>NZ_LM997411.1|WP_009060321.1|2379916_2380588_+|imidazole-glycerol-phosphate-synthase-subunit-HisH
MQNRFEQKSQPVLPVGIIDYGMGNLQSVEKAFESLSCKVERLFSPPNHYNFLAIVLPGVGAFGDGIKGLEAKGFLPFLENWISKDLPFLGICLGYQLLFEESLESKGAKGIGIFKGKVVRFPESKEKVPHIGWNSVEVLKKSAYLDGISSGDYFYFVHSYYPEVIQKEIILLQTTYCVPFASAIARGNLLATQFHPEKSHKKGIQLLKNFLIHSTIHRPLLSI
>NZ_LM997411.1|WP_009060323.1|2380595_2381315_+|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase
MKIYAAIDLYKGQVVRLRQGKLEALTVYSSDPLQTAQLWEDQGADGLHIVDLEGAFEGKPKQLSVLEKIAQQTHLPIQYGGGLRTEEDVFKAIENGAQRVVIGSRLLTDPSFLEKISGAVGSERIVAAIDAKDGQILMEGWTKESTYRMETFVKILEKSGAGFLLYTNVLTDGTLEGPDIQGTKKLVENSALPVFASGGIGCLRDVEELQKIKGLYGAILGKSLYEKKISIQTIKNISG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349325	Cyanophage S-RIM12 isolate W1_24_0910, complete genome	25763-25802	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349326	Cyanophage S-RIM12 isolate WH_05_0310, complete genome	25853-25892	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349327	Cyanophage S-RIM12 isolate WH_07_0310, complete genome	24905-24944	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349322	Cyanophage S-RIM12 isolate Sn_31_0910, complete genome	25766-25805	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349320	Cyanophage S-RIM12 isolate RW_29_1109, complete genome	25326-25365	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349310	Cyanophage S-RIM12 isolate RW_01_0310, complete genome	25659-25698	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349321	Cyanophage S-RIM12 isolate Sn_07_0910, complete genome	25659-25698	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349324	Cyanophage S-RIM12 isolate W1_12_0610, complete genome	25277-25316	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349314	Cyanophage S-RIM12 isolate RW_07_1112, complete genome	25326-25365	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349308	Cyanophage S-RIM12 isolate Np_15_0310, complete genome	25853-25892	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349316	Cyanophage S-RIM12 isolate RW_22_0110, complete genome	25326-25365	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349312	Cyanophage S-RIM12 isolate RW_04_0709, complete genome	25329-25368	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349315	Cyanophage S-RIM12 isolate RW_14_0101, complete genome	25332-25371	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349317	Cyanophage S-RIM12 isolate RW_25_0210, complete genome	25332-25371	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349311	Cyanophage S-RIM12 isolate RW_04_0310, complete genome	25853-25892	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349323	Cyanophage S-RIM12 isolate W1_08_0910, complete genome	25852-25891	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349313	Cyanophage S-RIM12 isolate RW_06_0310, complete genome	25852-25891	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	NC_015285	Prochlorococcus phage Syn33, complete genome	25325-25364	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349309	Cyanophage S-RIM12 isolate Np_22_1112, complete genome	25320-25359	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349319	Cyanophage S-RIM12 isolate RW_28_1109, complete genome	25311-25350	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349307	Cyanophage S-RIM12 isolate Np_14_0310, complete genome	25320-25359	11	0.725
NZ_LM997411_2	2.8\|2370167\|40\|NZ_LM997411\|PILER-CR,CRISPRCasFinder,CRT	2370167-2370206	40	KX349318	Cyanophage S-RIM12 isolate RW_27_0310, complete genome	25392-25431	11	0.725

1. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349325 (Cyanophage S-RIM12 isolate W1_24_0910, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

2. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349326 (Cyanophage S-RIM12 isolate WH_05_0310, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

3. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349327 (Cyanophage S-RIM12 isolate WH_07_0310, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

4. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349322 (Cyanophage S-RIM12 isolate Sn_31_0910, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

5. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349320 (Cyanophage S-RIM12 isolate RW_29_1109, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

6. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349310 (Cyanophage S-RIM12 isolate RW_01_0310, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

7. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349321 (Cyanophage S-RIM12 isolate Sn_07_0910, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

8. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349324 (Cyanophage S-RIM12 isolate W1_12_0610, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

9. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349314 (Cyanophage S-RIM12 isolate RW_07_1112, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

10. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349308 (Cyanophage S-RIM12 isolate Np_15_0310, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

11. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349316 (Cyanophage S-RIM12 isolate RW_22_0110, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

12. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349312 (Cyanophage S-RIM12 isolate RW_04_0709, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

13. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349315 (Cyanophage S-RIM12 isolate RW_14_0101, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

14. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349317 (Cyanophage S-RIM12 isolate RW_25_0210, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

15. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349311 (Cyanophage S-RIM12 isolate RW_04_0310, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

16. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349323 (Cyanophage S-RIM12 isolate W1_08_0910, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

17. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349313 (Cyanophage S-RIM12 isolate RW_06_0310, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

18. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to NC_015285 (Prochlorococcus phage Syn33, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

19. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349309 (Cyanophage S-RIM12 isolate Np_22_1112, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

20. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349319 (Cyanophage S-RIM12 isolate RW_28_1109, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

21. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349307 (Cyanophage S-RIM12 isolate Np_14_0310, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

22. spacer 2.8|2370167|40|NZ_LM997411|PILER-CR,CRISPRCasFinder,CRT matches to KX349318 (Cyanophage S-RIM12 isolate RW_27_0310, complete genome) position: , mismatch: 11, identity: 0.725

ctgctatttcaccttcaccttctaacttgaaccgcttctc	CRISPR spacer
catctatttcaccttcaacttctaactttaacgacaggaa	Protospacer
*  ************** ********** *** .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

550346 : 559171

Bacillus_virus(40.0%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009061548.1\|550346_551051_-	response regulator	W8CYM9	Bacillus_phage	2.7e-34	37.2
WP_009061545.1\|551367_553890_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	2.1e-12	45.1
WP_009061544.1\|553926_556533_+	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	3.5e-119	33.9
WP_045086469.1\|556800_557031_-	hypothetical protein	NA	NA	NA	NA
WP_009061542.1\|557068_558049_-	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	8.6e-39	34.1
WP_009061541.1\|558211_559171_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	4.8e-10	32.8

DBSCAN-SWA_2

789151 : 845364

Escherichia_phage(11.11%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079199581.1\|789151_789553_-\|transposase	transposase	NA	NA	NA	NA
WP_079199582.1\|789553_790087_-\|transposase	transposase	A0A077SL42	Escherichia_phage	3.5e-10	33.3
WP_079199583.1\|790371_790644_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_079199584.1\|790653_791109_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	1.1e-23	44.4
WP_009059447.1\|791431_791767_+	hypothetical protein	NA	NA	NA	NA
WP_009059446.1\|791759_792659_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_009059445.1\|792803_793250_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_009059444.1\|793501_794176_+	lipoate--protein ligase family protein	NA	NA	NA	NA
WP_009059443.1\|794186_795293_-	alanine dehydrogenase	NA	NA	NA	NA
WP_009059440.1\|795423_796044_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_045086506.1\|796654_796858_+	hypothetical protein	NA	NA	NA	NA
WP_009059438.1\|796854_797826_+	PhoH family protein	H6X2N1	Pseudomonas_phage	6.1e-45	49.5
WP_009059436.1\|797822_799442_+	HDIG domain-containing protein	NA	NA	NA	NA
WP_009059435.1\|799434_799767_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_009059434.1\|799770_800325_+	DNA repair protein RecO	NA	NA	NA	NA
WP_009059433.1\|800361_802530_-	AMP-binding protein	NA	NA	NA	NA
WP_009059431.1\|802612_803737_-	glycoside hydrolase family 3 protein	NA	NA	NA	NA
WP_009059427.1\|804143_804419_+	acylphosphatase	NA	NA	NA	NA
WP_009059426.1\|804668_805142_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_009059425.1\|805250_806279_+	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_009059424.1\|806307_807822_+	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	7.9e-07	35.4
WP_009059423.1\|807890_808103_-	hypothetical protein	NA	NA	NA	NA
WP_009059422.1\|808243_811027_-	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_048814672.1\|811184_811868_+	hypothetical protein	NA	NA	NA	NA
WP_009059418.1\|812315_813263_+	tyrosine recombinase XerC	A0A1I9SC88	Mycobacterium_phage	4.0e-09	26.9
WP_009059416.1\|813240_814653_+	glycosyltransferase	NA	NA	NA	NA
WP_009059415.1\|814695_815715_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	7.9e-19	28.8
WP_045086508.1\|815764_816166_+	hypothetical protein	NA	NA	NA	NA
WP_009059414.1\|816162_816957_+	ABC transporter permease	NA	NA	NA	NA
WP_009059413.1\|816953_817631_+	SCO family protein	NA	NA	NA	NA
WP_009059412.1\|817718_818144_+	DUF420 domain-containing protein	NA	NA	NA	NA
WP_009059410.1\|818457_819276_+	hypothetical protein	NA	NA	NA	NA
WP_009059409.1\|819326_820772_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_009059408.1\|820915_821821_-\|protease	protease HtpX	NA	NA	NA	NA
WP_009059407.1\|821906_823208_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_079199469.1\|823544_824411_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_009059403.1\|824657_825533_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_009059401.1\|825590_825866_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_009059399.1\|826071_828249_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	2.9e-79	33.1
WP_009059397.1\|828245_829511_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.7e-75	45.3
WP_009059396.1\|829807_831379_-	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_009059395.1\|831502_832684_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_009059393.1\|832686_834714_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_009059391.1\|834745_835294_-	hypothetical protein	NA	NA	NA	NA
WP_009059389.1\|835323_836235_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_045086835.1\|836270_837302_-	rod shape-determining protein	NA	NA	NA	NA
WP_009059385.1\|837576_838317_+	type I 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_009059383.1\|838362_839928_-	hypothetical protein	NA	NA	NA	NA
WP_009059381.1\|839954_840770_-	chorismate mutase	NA	NA	NA	NA
WP_009059379.1\|840783_841755_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_009059377.1\|841837_842305_-	pilus assembly protein CpaF	NA	NA	NA	NA
WP_009059375.1\|842675_844223_+\|protease	DegQ family serine endoprotease	W5SAB9	Pithovirus	5.1e-09	28.3
WP_009059373.1\|844260_845025_+	type III pantothenate kinase	NA	NA	NA	NA
WP_079199585.1\|844857_845364_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1883344 : 1933627

Catovirus(22.22%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009061339.1\|1883344_1883650_-\|protease	ATP-dependent Clp protease adapter ClpS	NA	NA	NA	NA
WP_009061341.1\|1884362_1885550_-	molybdopterin-synthase adenylyltransferase MoeB	A0A1V0SAV8	Catovirus	3.5e-10	28.8
WP_009061343.1\|1885729_1886866_+	ribonuclease D	NA	NA	NA	NA
WP_009061344.1\|1886973_1887720_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_009061345.1\|1887749_1890497_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	8.5e-84	38.4
WP_009061347.1\|1890583_1890796_+	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_079199491.1\|1890957_1891260_-\|transposase	transposase	NA	NA	NA	NA
WP_045086679.1\|1891644_1891953_-	hypothetical protein	NA	NA	NA	NA
WP_009061352.1\|1892698_1894084_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_009061354.1\|1894177_1894966_+	MBL fold metallo-hydrolase	A0A2H4J3R0	uncultured_Caudovirales_phage	4.1e-31	35.7
WP_009061356.1\|1894994_1895291_-	hypothetical protein	NA	NA	NA	NA
WP_009061357.1\|1895412_1896108_+	DsbA family protein	NA	NA	NA	NA
WP_045086680.1\|1896275_1896857_+	hypothetical protein	NA	NA	NA	NA
WP_009061367.1\|1897030_1898065_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_009061368.1\|1898278_1898659_+	DUF302 domain-containing protein	NA	NA	NA	NA
WP_009061369.1\|1898729_1900565_+	ribonucleoside triphosphate reductase	D9ZNH0	Clostridium_phage	2.1e-139	42.8
WP_009061370.1\|1900545_1901238_+	anaerobic ribonucleoside-triphosphate reductase activating protein	NA	NA	NA	NA
WP_009061371.1\|1901262_1901703_+	SRPBCC domain-containing protein	NA	NA	NA	NA
WP_009061372.1\|1901718_1901985_+	hypothetical protein	NA	NA	NA	NA
WP_045086681.1\|1902209_1902638_+	hypothetical protein	NA	NA	NA	NA
WP_009061375.1\|1902777_1903362_+	carbonic anhydrase	NA	NA	NA	NA
WP_009061376.1\|1903844_1904858_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_079199492.1\|1904983_1905271_-	hypothetical protein	NA	NA	NA	NA
WP_045086683.1\|1905811_1906003_-	hypothetical protein	NA	NA	NA	NA
WP_045086684.1\|1905992_1906229_-	hypothetical protein	NA	NA	NA	NA
WP_009060748.1\|1906899_1907202_-	GYD domain-containing protein	NA	NA	NA	NA
WP_009060746.1\|1907285_1907978_-	endonuclease V	NA	NA	NA	NA
WP_009060744.1\|1907980_1908322_-	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_009060742.1\|1908326_1908806_-\|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_009060740.1\|1908844_1910923_-	glucans biosynthesis glucosyltransferase MdoH	NA	NA	NA	NA
WP_009060738.1\|1910945_1911338_-	hypothetical protein	NA	NA	NA	NA
WP_009060734.1\|1911334_1912870_-	glucan biosynthesis protein D	NA	NA	NA	NA
WP_009060733.1\|1912853_1914383_-	glucan biosynthesis protein	NA	NA	NA	NA
WP_009060731.1\|1914532_1915342_-	hydrogenase	NA	NA	NA	NA
WP_009060729.1\|1915577_1916375_-	Mut7-C ubiquitin/RNAse domain-containing protein	NA	NA	NA	NA
WP_009060727.1\|1916371_1917511_-	DsbA family protein	NA	NA	NA	NA
WP_009060724.1\|1917548_1918166_-	hypothetical protein	NA	NA	NA	NA
WP_009060723.1\|1918320_1919619_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_009060720.1\|1919615_1921451_-	bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_009060717.1\|1921479_1922523_+	LOG family protein	F4YCQ1	Synechococcus_phage	9.0e-18	32.9
WP_009060713.1\|1922557_1923187_+	HAD family hydrolase	NA	NA	NA	NA
WP_009060712.1\|1923183_1924050_-	metal ABC transporter permease	NA	NA	NA	NA
WP_009060710.1\|1924057_1924819_-	metal ABC transporter ATP-binding protein	A0A1V0SBM3	Catovirus	3.4e-14	30.1
WP_009060708.1\|1924799_1925777_-	zinc ABC transporter solute-binding protein	NA	NA	NA	NA
WP_009060706.1\|1925885_1926326_-	hypothetical protein	NA	NA	NA	NA
WP_009060705.1\|1926418_1927234_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_009060704.1\|1927615_1928605_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_009060702.1\|1928612_1930550_-	UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase	NA	NA	NA	NA
WP_079199611.1\|1931224_1931590_+\|transposase	IS200/IS605 family transposase	A0A0H3UZM0	Geobacillus_virus	1.4e-15	44.7
WP_079199612.1\|1931542_1931998_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.6e-25	46.0
WP_079199613.1\|1932007_1933627_+\|transposase	transposase	A0A068A1P5	Thermus_phage	9.9e-32	29.8

DBSCAN-SWA_4

2015011 : 2077291

Escherichia_phage(14.29%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079199614.1\|2015011_2015476_-\|transposase	transposase	NA	NA	NA	NA
WP_079199615.1\|2015476_2016010_-\|transposase	transposase	A0A077SL42	Escherichia_phage	2.1e-10	33.3
WP_079199616.1\|2016022_2016433_+	hypothetical protein	NA	NA	NA	NA
WP_009060575.1\|2017578_2018259_+	response regulator transcription factor	NA	NA	NA	NA
WP_009060573.1\|2018274_2018463_-	hypothetical protein	NA	NA	NA	NA
WP_009060571.1\|2018566_2019340_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_009060564.1\|2020351_2021035_-	hydrolase	NA	NA	NA	NA
WP_009060562.1\|2021157_2022015_-	transglutaminase family protein	NA	NA	NA	NA
WP_009060560.1\|2022024_2024424_-	circularly permuted type 2 ATP-grasp protein	NA	NA	NA	NA
WP_009060558.1\|2024500_2025412_-	alpha-E domain-containing protein	NA	NA	NA	NA
WP_009060556.1\|2025417_2026935_-	hypothetical protein	NA	NA	NA	NA
WP_009060555.1\|2027269_2029441_-	peptidase M50	NA	NA	NA	NA
WP_009060553.1\|2029841_2030750_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_009060551.1\|2030833_2032963_-	biotin/lipoyl-binding protein	NA	NA	NA	NA
WP_009060549.1\|2033002_2033308_-	PqqD family protein	NA	NA	NA	NA
WP_009060548.1\|2033323_2034340_-	radical SAM protein	NA	NA	NA	NA
WP_009060546.1\|2034342_2034810_-	hypothetical protein	NA	NA	NA	NA
WP_009060544.1\|2034816_2035206_-	hypothetical protein	NA	NA	NA	NA
WP_009060542.1\|2035256_2035448_-	hypothetical protein	NA	NA	NA	NA
WP_009060541.1\|2035517_2035910_-	hypothetical protein	NA	NA	NA	NA
WP_009060539.1\|2036004_2036349_-	hypothetical protein	NA	NA	NA	NA
WP_009060537.1\|2036513_2037755_+	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_009060533.1\|2038959_2039496_-	NADH-quinone oxidoreductase subunit B family protein	NA	NA	NA	NA
WP_009060531.1\|2039485_2041018_-	hydrogenase expression protein HypE	NA	NA	NA	NA
WP_009060529.1\|2041022_2042501_-	hydrogenase 4 subunit F	NA	NA	NA	NA
WP_009060528.1\|2042454_2043117_-	hydrogenase-4 component E	NA	NA	NA	NA
WP_009060526.1\|2043113_2044064_-	formate hydrogenlyase	NA	NA	NA	NA
WP_009060524.1\|2044060_2046061_-	hydrogenase 4 subunit B	NA	NA	NA	NA
WP_009060522.1\|2046523_2047195_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_009060520.1\|2047209_2048346_-	alkene reductase	NA	NA	NA	NA
WP_045086695.1\|2048372_2048573_+	hypothetical protein	NA	NA	NA	NA
WP_009060518.1\|2048777_2050001_+	cation:proton antiporter	NA	NA	NA	NA
WP_079199617.1\|2050209_2051235_-\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	6.5e-13	32.1
WP_079199618.1\|2051389_2051587_-	hypothetical protein	NA	NA	NA	NA
WP_079199619.1\|2051586_2051793_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_079199620.1\|2051802_2052258_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.6e-25	46.0
WP_009060791.1\|2052408_2053605_-	L-2-hydroxyglutarate oxidase	NA	NA	NA	NA
WP_009060792.1\|2053819_2054752_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_009060793.1\|2054748_2055294_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	6.3e-23	37.6
WP_009060795.1\|2055304_2056300_-	NAD(P)-dependent oxidoreductase	A0A2D2W2J1	Stenotrophomonas_phage	2.0e-11	26.2
WP_009060797.1\|2056306_2057104_-	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_079199621.1\|2057167_2057572_-	hypothetical protein	NA	NA	NA	NA
WP_009060801.1\|2057853_2058201_-	hypothetical protein	NA	NA	NA	NA
WP_009060805.1\|2059706_2063585_+	hypothetical protein	A0A2H4PQV1	Staphylococcus_phage	4.2e-20	31.0
WP_045086697.1\|2064305_2065925_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_009060075.1\|2068569_2071047_-	glycosyltransferase	NA	NA	NA	NA
WP_045086700.1\|2072215_2072416_+	hypothetical protein	NA	NA	NA	NA
WP_079199477.1\|2072522_2072726_+	hypothetical protein	NA	NA	NA	NA
WP_009060068.1\|2073483_2074479_+	zinc-dependent alcohol dehydrogenase family protein	A0A2K9L7I1	Tupanvirus	1.7e-18	29.1
WP_009060067.1\|2074924_2075110_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_009060066.1\|2075190_2076117_-	OmpA family protein	NA	NA	NA	NA
WP_009060065.1\|2076172_2077291_-\|protease	serine protease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LM997411

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection