CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP004380	Burkholderia pseudomallei 1026b chromosome 2, complete sequence	4 crisprs	csa3,cas3,DinG	2	4	4	0
NZ_CP004379	Burkholderia pseudomallei 1026b chromosome 1, complete sequence	2 crisprs	WYL,DEDDh,DinG,csa3	1	2	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP004380_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004380_1

333415-333507

Orphan

Consensus_repeat	Method
TCGCCGCCGCGCGCGACGACGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP004380_1

>merge|NZ_CP004380|1|333415-333507|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGCTGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGATCGCCGCCGCGCGCGCCGACGCGC

>NZ_CP004380|1|1|333415-333507|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGC	TGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGA
TCGCCGCCGCGCGCGCCGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004380.1\|WP_004524985.1\|331944_332253_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NZ_CP004380.1\|WP_162130316.1\|322572_323964_+\|hexose-kinase	unknown	unknown	gnl\|CDD\|238570
NZ_CP004380.1\|WP_004553631.1\|338703_339213_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004553635.1\|333942_335961_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NZ_CP004380.1\|WP_004188221.1\|331010_331466_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NZ_CP004380.1\|WP_004553633.1\|337040_338066_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NZ_CP004380.1\|WP_004188840.1\|327280_329074_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|213656
NZ_CP004380.1\|WP_004187193.1\|332947_333196_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NZ_CP004380.1\|WP_004530245.1\|343653_344778_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NZ_CP004380.1\|WP_004524981.1\|329205_329463_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004524995.1\|348046_349120_-\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|235136
NZ_CP004380.1\|WP_004524980.1\|325866_327270_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NZ_CP004380.1\|WP_004187346.1\|332249_332951_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NZ_CP004380.1\|WP_045586909.1\|338142_338646_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004553629.1\|344780_348050_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP004380.1\|WP_004533337.1\|335957_336806_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NZ_CP004380.1\|WP_004529184.1\|324691_325870_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NZ_CP004380.1\|WP_004524990.1\|339753_341319_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NZ_CP004380.1\|WP_004529183.1\|329434_331021_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NZ_CP004380.1\|WP_004553630.1\|341668_343504_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425

Protein	Function_ID	Function_description	E-value
NZ_CP004380.1\|WP_004524985.1\|331944_332253_+\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	4.12229e-10
NZ_CP004380.1\|WP_162130316.1\|322572_323964_+\|hexose-kinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	2.65378e-109
NZ_CP004380.1\|WP_004553635.1\|333942_335961_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NZ_CP004380.1\|WP_004188221.1\|331010_331466_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63
NZ_CP004380.1\|WP_004553633.1\|337040_338066_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP004380.1\|WP_004188840.1\|327280_329074_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NZ_CP004380.1\|WP_004187193.1\|332947_333196_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	4.45015e-37
NZ_CP004380.1\|WP_004530245.1\|343653_344778_-\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	4.38049e-26
NZ_CP004380.1\|WP_004524995.1\|348046_349120_-\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	1.83012e-39
NZ_CP004380.1\|WP_004524980.1\|325866_327270_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NZ_CP004380.1\|WP_004187346.1\|332249_332951_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NZ_CP004380.1\|WP_004553629.1\|344780_348050_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.16978e-92
NZ_CP004380.1\|WP_004533337.1\|335957_336806_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	4.46992e-34
NZ_CP004380.1\|WP_004529184.1\|324691_325870_-\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NZ_CP004380.1\|WP_004524990.1\|339753_341319_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.47951e-79
NZ_CP004380.1\|WP_004529183.1\|329434_331021_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NZ_CP004380.1\|WP_004553630.1\|341668_343504_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	1.97454e-132

>NZ_CP004380.1|WP_004187193.1|332947_333196_+|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLFANPFVK
>NZ_CP004380.1|WP_004187346.1|332249_332951_+|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NZ_CP004380.1|WP_004524985.1|331944_332253_+|membrane-protein
MIEMWETARASFDGIAAAIGLALGFVAGACHFVSLGWNSRLFVAGRAGVALALQLARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NZ_CP004380.1|WP_004188221.1|331010_331466_+|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NZ_CP004380.1|WP_004529183.1|329434_331021_+|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAACAERDASDVGDARDEGAGRVVAVRGAVIDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
>NZ_CP004380.1|WP_004524981.1|329205_329463_-|hypothetical-protein
MPFVACGSATVAPVWLVRRWLHHNGARRPPADLGQETGNRQTKRGIAQSETIDASASGADTVRAASIVDSNQIPQTYAWLQWPCQ
>NZ_CP004380.1|WP_004188840.1|327280_329074_-|alpha/beta-fold-hydrolase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NZ_CP004380.1|WP_004524980.1|325866_327270_-|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGARLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NZ_CP004380.1|WP_004529184.1|324691_325870_-|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHLRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NZ_CP004380.1|WP_162130316.1|322572_323964_+|hexose-kinase
MRGACASRAMFDTGGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSSRPAPVLMVRRRIERKHCGACPPRSTREPRTRASRCVVFPSRIPTLKPNVTMSEIVTLTPNPAIDVATCVERVTDTRKLRCGPARRDPGGGGINVARVLTRLGADCSAVYLAGGGTGLALRGLLADEGVRAHGIDIAGETRENFSVLETSTGREFRFVLPGPALAAHEWPRCVEALGRLADASRYLVMSGSLPPGMPDDCYARLARRASARGVRTVVDTSGPALAAALDAGVYLVKPSLGELRALTGLPLEDDGARLAAARAIVAGGRAQIVALTLGDAGALVVSRDDAVRLPGVKVAVRSAIGAGDSFVAGLVAALNRGANVADAARHALAAASASLLSTGTALGTKEDIARIYRELPGMIDA
>NZ_CP004380.1|WP_004553635.1|333942_335961_+|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAAAADAATGAGWLARRRGALARVALAPVAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGALDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSCEVSHEADRDAAADAARVAGRAPGRAEPDRAAPRAMPDGPPRAQADGDRASASRPRPDARGDAARTAPSPQGGADANVDADANVDAEAEARHKR
>NZ_CP004380.1|WP_004533337.1|335957_336806_+|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGDTAAGARAAPRARLVVVLCSEQGFVGAYNAQLIEHATRPEPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NZ_CP004380.1|WP_004553633.1|337040_338066_+|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGAGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGATFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NZ_CP004380.1|WP_045586909.1|338142_338646_+|hypothetical-protein
MRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDTHPGDVTPVHVSRPVQFAVPADEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NZ_CP004380.1|WP_004553631.1|338703_339213_-|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAAGGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVGTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLDGTDPTIPAFP
>NZ_CP004380.1|WP_004524990.1|339753_341319_+|methyl-accepting-chemotaxis-protein
MPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NZ_CP004380.1|WP_004553630.1|341668_343504_-|response-regulator
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHRALGESVHVDADLREDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRKKTAAARVQR
>NZ_CP004380.1|WP_004530245.1|343653_344778_-|ABC-transporter-permease
MRRLAIVYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMDAGDFTFVLDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRQFLILAVIGTALFLLSLKRFRKTIGQMA
>NZ_CP004380.1|WP_004553629.1|344780_348050_-|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQDAQDAQGGAGERPGSSERAAGESLAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGPEVGPEVGPEVGSEVGSEVASEAGLAAGAESGSERGVAHGAERAREPAADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPPSHAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHDLYSQFWPLAACVPVILGATILLLKKQER
>NZ_CP004380.1|WP_004524995.1|348046_349120_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MIQVTRKQIVAAAAVVVVALGAYYGWTLLRHQGPGDGFASGNGRIEATEIDVATKLPGRIDAILVDEGDFVKAGQPLANMQIQVLRAQYDEATAQRQRALNTAAGVQSQVAQRKSDKAAAQAMVVLRESELDAAERRLARSQTLSREGASSLQELDDDRARARSAQAAVSAAAAQVAAAQAAIEATEAQLVAAHSAVTAADATVARVQADIDDSQLASPRDGRVQYRVAQPGEVLPAGGKVLNLVDLSDVYMTFFLPETVVGRVALGADARIILDAAPNYVIPATVSFVSSTAQFTPKTVETANERQKLMFRVKARIDRELLQKHLKLVKTGLPGVAWVRVDPSKPWPAQLMVKVPQ

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Crispr_ID: NZ_CP004380_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004380_2

1586392-1586494

Orphan

Consensus_repeat	Method
TGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTGGCCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP004380_2

>merge|NZ_CP004380|2|1586392-1586494|CRISPRCasFinder
TGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCG

>NZ_CP004380|2|2|1586392-1586494|CRISPRCasFinder
TGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGC	GGTGCTTGCGGTGCTTGCGGTGCT
TGCGGTGCTTGCGGTGCTTGCGGTGCTTGCGGTGCTTGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004380.1\|WP_004528251.1\|1615232_1616492_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NZ_CP004380.1\|WP_004553359.1\|1612653_1613838_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|272922
NZ_CP004380.1\|WP_080340281.1\|1562633_1578665_-\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|237108
NZ_CP004380.1\|WP_004553366.1\|1552142_1554014_+\|chloride-channel-protein	unknown	unknown	gnl\|CDD\|238233
NZ_CP004380.1\|WP_004546727.1\|1554683_1556126_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_CP004380.1\|WP_004524104.1\|1551694_1552108_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_CP004380.1\|WP_004553367.1\|1550360_1551554_+\|HPP-family-protein	unknown	unknown	gnl\|CDD\|225979
NZ_CP004380.1\|WP_004524106.1\|1547446_1548532_+\|ionic-transporter-y4hA	unknown	unknown	gnl\|CDD\|223464
NZ_CP004380.1\|WP_004531777.1\|1619604_1621284_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP004380.1\|WP_004198341.1\|1550035_1550299_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004524091.1\|1621449_1622454_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl\|CDD\|239607
NZ_CP004380.1\|WP_004553360.1\|1611036_1612269_+\|sodium/hydrogen-exchanger	unknown	unknown	gnl\|CDD\|215608
NZ_CP004380.1\|WP_004198264.1\|1618092_1618332_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180851
NZ_CP004380.1\|WP_004551645.1\|1557949_1562650_-\|DUF2156-domain-containing-protein	unknown	unknown	gnl\|CDD\|238429
NZ_CP004380.1\|WP_004198262.1\|1616485_1617256_+\|enoyl-CoA-hydratase/isomerase	unknown	unknown	gnl\|CDD\|235938
NZ_CP004380.1\|WP_004539120.1\|1618318_1619563_+\|polyketide-beta-ketoacyl:ACP-synthase	unknown	unknown	gnl\|CDD\|180839
NZ_CP004380.1\|WP_004198340.1\|1549043_1550015_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP004380.1\|WP_004549222.1\|1556208_1557867_-\|halogenase	unknown	unknown	gnl\|CDD\|223717
NZ_CP004380.1\|WP_004198258.1\|1614887_1615121_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004532917.1\|1617256_1618039_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|235936

Protein	Function_ID	Function_description	E-value
NZ_CP004380.1\|WP_004528251.1\|1615232_1616492_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	7.17071e-102
NZ_CP004380.1\|WP_080340281.1\|1562633_1578665_-\|non-ribosomal-peptide-synthetase	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP004380.1\|WP_004553366.1\|1552142_1554014_+\|chloride-channel-protein	gnl\|CDD\|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	7.50476e-100
NZ_CP004380.1\|WP_004546727.1\|1554683_1556126_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.18813e-61
NZ_CP004380.1\|WP_004553360.1\|1611036_1612269_+\|sodium/hydrogen-exchanger	gnl\|CDD\|215608	PLN03159, PLN03159, cation/H(+) antiporter 15; Provisional.	4.27436e-41
NZ_CP004380.1\|WP_004553367.1\|1550360_1551554_+\|HPP-family-protein	gnl\|CDD\|225979	COG3448, COG3448, CBS-domain-containing membrane protein [Signal transduction mechanisms].	4.83609e-133
NZ_CP004380.1\|WP_004524106.1\|1547446_1548532_+\|ionic-transporter-y4hA	gnl\|CDD\|223464	COG0387, ChaA, Ca2+/H+ antiporter [Inorganic ion transport and metabolism].	2.6957e-73
NZ_CP004380.1\|WP_004531777.1\|1619604_1621284_+\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00218866
NZ_CP004380.1\|WP_004524104.1\|1551694_1552108_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	2.14376e-10
NZ_CP004380.1\|WP_004524091.1\|1621449_1622454_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl\|CDD\|239607	cd03531, Rieske_RO_Alpha_KSH, The alignment model represents the N-terminal rieske iron-sulfur domain of KshA, the oxygenase component of 3-ketosteroid 9-alpha-hydroxylase (KSH). The terminal oxygenase component of KSH is a key enzyme in the microbial steroid degradation pathway, catalyzing the 9 alpha-hydroxylation of 4-androstene-3,17-dione (AD) and 1,4-androstadiene-3,17-dione (ADD). KSH is a two-component class IA monooxygenase, with terminal oxygenase (KshA) and oxygenase reductase (KshB) components. KSH activity has been found in many actino- and proteo- bacterial genera including Rhodococcus, Nocardia, Arthrobacter, Mycobacterium, and Burkholderia.	6.90109e-36
NZ_CP004380.1\|WP_004553359.1\|1612653_1613838_+\|ACP-S-malonyltransferase	gnl\|CDD\|272922	TIGR00128, Malonyl_CoA-acyl_carrier_protein_transacylase, malonyl CoA-acyl carrier protein transacylase. This enzyme of fatty acid biosynthesis transfers the malonyl moeity from coenzyme A to acyl-carrier protein. The seed alignment for this family of proteins contains a single member each from a number of bacterial species but also an additional pair of closely related, uncharacterized proteins from B. subtilis, one of which has a long C-terminal extension. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.08999e-102
NZ_CP004380.1\|WP_004198264.1\|1618092_1618332_+\|acyl-carrier-protein	gnl\|CDD\|180851	PRK07117, PRK07117, acyl carrier protein; Validated.	1.31913e-39
NZ_CP004380.1\|WP_004551645.1\|1557949_1562650_-\|DUF2156-domain-containing-protein	gnl\|CDD\|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	6.63996e-157
NZ_CP004380.1\|WP_004198262.1\|1616485_1617256_+\|enoyl-CoA-hydratase/isomerase	gnl\|CDD\|235938	PRK07112, PRK07112, enoyl-CoA hydratase/isomerase.	4.21258e-167
NZ_CP004380.1\|WP_004539120.1\|1618318_1619563_+\|polyketide-beta-ketoacyl:ACP-synthase	gnl\|CDD\|180839	PRK07103, PRK07103, polyketide beta-ketoacyl:acyl carrier protein synthase; Validated.	0
NZ_CP004380.1\|WP_004198340.1\|1549043_1550015_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.78138e-66
NZ_CP004380.1\|WP_004549222.1\|1556208_1557867_-\|halogenase	gnl\|CDD\|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	2.43201e-19
NZ_CP004380.1\|WP_004532917.1\|1617256_1618039_+\|enoyl-CoA-hydratase	gnl\|CDD\|235936	PRK07110, PRK07110, polyketide biosynthesis enoyl-CoA hydratase; Validated.	9.84342e-151

>NZ_CP004380.1|WP_080340281.1|1562633_1578665_-|non-ribosomal-peptide-synthetase
MNAIISDVIRAYREGKLTTADLASELRRGAGDGAGLPLSEGQRGIWALHALHEDRGAYNVPLCFAVRDLRADAFRRALRFVARQYPSLCAAIRVIDGEPRRVQPAGATLEPIEATLADTLGPDADEAAILAWLREQARQPFSLEDGPLCRVHLLDLAGWRARDAAAASRFGAAHTIVSLHVHHLVLDGQSLLLLIGTLLDAYRALVDGVEPAPRAPAATHDDFVAEERALLDSDEGARRIAYWRRQLDALPPALELPASAPAAAERAAGDAWHAVPLDAARSARVAAFVQSNHLGAAAFFLGMFKLLLHRYTGEPDIVVGMPADARPSQRYRDALGFFVNMLPLRTRLAGETAVVAMLERVQRELVDAMAMQYPFGALVRELGLQGAEDGAPMYRIAFMYQDFLARLRFGDDVEPIGEIRQAGEYELVLEVIEGAAPGGPARFALNWKYDGARYRAAAVEAMARHYLTLLDGVLAAPAARVADCPMLPAAERERLLALGRGPRADHARERRVHDLIDARAQQAPHAIAVSCGGRSLDYARLKADSDALAQRLRACGIGAGDFVAVRLDRSTALVVGLLAVLKAGAAYVPLDPDYPDDWAAQMLGDCRPAAILTRAALAAGAHALARRVAADGPPAVIALDDAADADTHAADGARAAAIAAARQAAASRAHAARAADLAYVIYTSGSTGAPKGVMVTHRALTNFLASMARRPGLHARDTLLAVTTYCFDIAALELFLPLVQGAHCVICDSASARDGGRLRELIDAARPTVMQATPSTWEMLLHAGWRNARRMRVLCGGDTLPDAVKARLLEDGGEVWNLYGPTETTIWSMVAPVTSERPTSIGAPIDNTRIRIVDAYGNPVPIGVPGELCIAGDGLAAGYLNRPDETAARFVDALPDVDGQARERHYRTGDLARWREDGEVEHLGRMDFQVKIRGHRVEVHDIERHLARHPAIRAAAVVARRHAGGDQLVAYYVRGDAAGHGGADDAPALAAELRGHLAGALPDYMIPALFLPIDALPMTHNGKLNRKALASRGIRLRVASSGERRAAPPRAPAAADIEARLLAICREVLKIDDIDRADGFFEVGGNSLSVALIASRVGAEFGLARLGAGAFFRYPTVAALAAHLGARLRGDAGAAEGADGADAGPAGADARASRPAQPRAAGPAARLPAALDDAIAIIGISCQFPGAQDHRAFWRNLRDGKSGARFYSEDELRAAGVPDTLIRDRHYVPMQQTIEGKDLFDRHFFRLTTKDAQLMDPQFRLLLQHAWKAIEDAGCTRERIADAGVYMSASNSYYQAMLRAAGTIDASDEYQAWLLAQGGTIPTRISYELGLTGPSLFIHSNCSSGLVSLSVAAKSLLQRESRCALVGAATVLPDADIGYVYQPGLNLSSDGRCRTFDENADGLTSGEGVAVLLVKRARDAIDDGDPIYALLRGIAVNNDGADKVGFYAPSVGGQADVIRKVLDATGIHPETIGYVEAHGTGTKLGDPVEVAALTDAYRRHTARTGFCAIGSVKPNIGHLDTVAGLSGCIKVALSLRHGEIAPSINYEKPNREIDFAHSPFYVVDRLTRWPAREPGAPRRAALSSFGIGGTNAHLILEAFERDEPPAGMRAPAARAARVIALSARTEERVRAQASQLLAFLEQEAGALPDFDGFAFTLQVGREAMRERVAFVADGYDALAAALARFLRGEPDAAACFTGARGGDSTLAALLDDTGDTGDTAAHGLIAAWCEQGKVAKIAALWAHGVNVDWRRLYGARAPVRVSLPTYPFAPERCEGVARRRAAAPAPRRAGVETAAARLHPLVHDDRSDGARRRFAATYSGEEFFLADHLIRGKRILPGVAYLEMARMAAVRAHGDGALSLHDVVWMTPIVVDGPCEVELSLEAAERAEAEGAAEAAAGVRTMRFNVTSGGGAGARRTNSQGTIRLAPGAAAPAAARVDVAALLARCTREIGAQRFYTFLDSGGGHYGPTFRSVAALHQGEREVLARLALPESVAHADAFVLHPSMMDAAFQIADSLILQPRANGGCLPFFVKELVVRRRPGRDAWVHVRLAGGDATLARYDIDLIDPDGTVCVSMREFSARAETAGGSGRPNTYRAAEWRAAERDGERDGNELSELNELNELNEGNEGNERRRAAPRVAVLDASPRLAHALRGIGVDALWLPADAAHAARGPALRDLDAALHAGAARDLLVLADERRELDDDALRAWLDGAPHAGGARRALVSIAGLADADARAVADIVERERHGRAADVRYDAGGARSVRGFADAAVARWLLDTDALRSGGVYWIAGANGPLGASLACHLATVERATVVLTDAHAIDAARLACLDGYRAGGARLEFIEGDAARDGAALAQRIRARHGRIDGVLHCAQHASAPTLAALAALDRATRADALDCFVACEARDADPDRDPAAALVARFVERRHARVQAGLGGGRTVAIAAHAALPWPDDAPLLRAGGIASQPALAIVQALHHALRSDEAMLAVGWGASAGGVDAGASKAANASNASNASNASNASDASDASNASNASNASNASNASNASNASNASNASNASNTSNTSNTSNTSNTSNAPSVAADLAAPAEPNARIPARARATPDTIAACLKAVIADVIRADVDEIDARQHFGEYGLDSLSLTSVSNRLNDAYRLDASPAGALNPTLFFEYPSVERMAAYLAEHHAARFADASAAPGADGAAECAPRPEAALNAEVEPGNGAAPAPEPEVGFRAGFEPVAPPMPRIEPTASTPPDQPAPQPGGAWHAGRGACPAADDDVAIIGISGRFPGARDVAEFGRNLFDGRDCIGEIPADRWDWRAYLGDPQHEAGKTNSKWGGFIDGIAEFDPLFFSLSPKEAYLLDPAHRLLLMHAWWAIEDAGYNPAALAGSRTALFAGIAQSGYADLRRQAGEGIEGNSFLGVVPSIALNRISHLLDLHGPSEPVETACSSSLVAMHRALVSLRCGDADMALVGGVQTILSPHAHIGFGKAGMLATDGRCKAFSSRADGFVRGEGIGMLFLKRLGDARRDGDAIYGVIRGSAVNHDGRSSSLTAPNPAAQRDVIVQAHMRAGVDPRSIGYIEAHGTGTKLGDPIEINALTQALDTLLRAQREEGAAYVPGACAIGSVKSNIGHLELAAGVSGVIKVLLQMANGRLAKSLHCDELNPYITLDGGPLRVVGANAAWPRPVDRDGREQPRRAGVSSFGIGGVNAHVVLEEYPEADARARDDGQPAAVLLSARDSQRLADYASALLAFVRERREAAAHAPPPRLSDLAYTLQVGREAMRERVGFVVTSLAQLEARLAAFVAGEPAGDGVYRGSVRPARGERAADADGLDRLVDIWLANRKHEALLGAWVKGAAIDWARLHAGGAPRRVHLPGYPFARERYWIAEPAPATGAPGEPAPPRMPTQPHGPTSDGRAESRHPLRRAADGRFLLDLDGDEAFLADHRVDGRRVLPGVAHLEIAYEAARRTFGPADAIRIRNLGWIRPIVADGALRIGVELSVTGAAEGAFRLYTTDPQHGRLTHSEGAIGRADVAQSARALDLGALRDAFATAERVDPAVWYDGFSRAGIDYGPSHRCLETCAVGPAGVLARVRLPAAEARAARPFTLHPGLMDAVLQAAIGLRKRAGGAPRGTPYLPFALDAVEILGGCGEAAWAWLRPSPRDAADASASRGDAGKPAAERIDIDVCDDAGRISVTLRGLTSRPLARRTAPAPEAGNPAGEVGEVADATDADAAEVREISDVSDVSNVSDVAPLADGDVGLLARTAVWSALTPAQWLADPASRPRAGARVFVLGGTAAQRREIARIHPGCEPLEENAADDGGDGADQQAHVDALRRRLAEGAPIDQLVWIAPPEPAADARAGLRGDAIVAAQEHGVLQLFRIVKLLLAAGYGGKPLDWTIVTRETHATSGIDEPSPTHAGVHGFVGSMAKEYRNWRVRLLDMPAREAWPIDAMFSTRFDPRGDALAYRRGRWLARELAAIDALPDGGCHVKTGGVYVVIGGAGGIGEVWSRWMMERYQARIVWIGRRDEDEQIRRKRERLARYGTPPVYLRADASERASLAAARERIAALRWDGRALPTSGVVHSAIVLADASLATMDEARFLAAWRSKADVGVRVAEVFGGDPLDFMLFFSSITSFGKTAGQANYAAGCAFKDAFAAHLGRTLPYPVKVMNWGYWGSVGVVSDETYRRRMASAGFGSIEPDEGMSALERLLASRVGQIAVLKTLRPNLVGDSRADRIRHYPGRDWPDAAPAPATAALQAALAARAGRWHAQASALALGNPELETLIARGLLAGVLPYLDAPGSVDARHARWFDESRAMLHGFGYLARDGAGDAPSWSLTDAGRAAAPHVWQDWERHALAWHDDERRVPMRLAHVCLRALPELLGGKRRATDVMFPGSSMALVEGLYKSNRKADLFNDVVHDAVLSYARALGRALDIVEVGAGTGGTTDGLLRKLVEQGIAVREYRYTDLSHAFLLHAREHYAPRAPFLTTGIFDVDKPIAAQRVPGGRYDVAVATNVLHATRDVRRALRNVKATLRAGGLLILNELSVKSLFSHVTFGLLDGWWMYEDADLRIPGSPGIDSSTWRRVLAEEGFEYVFFPAQGLHAHGQQVIVAQSDGVVRQPRAAAAPGAGAAASPSGGTQAAVPARRAAAASGAPRVEAIPPAAVAPAAFDAATAAPPGTAAAAATAVPADGRSALAHASSPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIEPDASFASYGVDSIMAMALIAALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTVPTEPTASPASSAPPAASPPQPGDAHALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIEPDASFASYGVDSIMAMALIAALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPAASPPQPGDAHALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGEYLLERQGQERACHASNV
>NZ_CP004380.1|WP_004551645.1|1557949_1562650_-|DUF2156-domain-containing-protein
MQATFNPDEVALAGDARRTDGDADRAAASPHGFRFVEKARIADEPGLSARLAARKGDAHQDGVFLDLWPSIFLSDEHGDHIHVLRDRGLLFVTRFVGAPQREAALLSALLDRARGEGRALCYLDMSNRRKPDIERECGLLSTPLGVVQTIDDIRRFTLDGPRMRKLRYLVSKFGRDPSCRVVEYTEPDPAVDGEIRAVMAAWSREKGVVNKVDAILADMRVGNLLKRYRVYLTYLGDRLQNVVVLSHIGEGYITDQEYFVPDMPLGGTEYAYATIIERLAAEGHRKFSLGLTWGLFEPEAGFSDAEGWALVNRTEGQLAQIFRRGVQNHQYKNKYCPAEYPLYLYRSADSRPQIIKQCMGQFFRNGVPYDEIARQIEADDARALAAAGAAPPRATHGGDEAEARSAPGGAPDDARADAPDDASFDAPDGAPIEVSDHAPGSTPPPRAARDERGGERDDGKGGQAGQADRSGKHDPADAHGRAASGTPDAARAPAPADIPDAFFDATQADPNAIRLDLVSDSWAHLGYPFIRERARRLLAGLASPHADPAAPCGLFGVDHCVLTTSGRNAERVFFNLFPAKRKTILQNIPFFSTRHNAAKAGFASVEIPDPRIFDPDCREIFRGGIDFARLREQLEARPDGVAMVLIELCNNASGGYPVPLAQIADVSALCRARGVPFVMDVTRIVRNAELIRRHEPGCANVGLWDTVARIVAHADVVFGSLCKDFGVSAGGIVAANDGRLIGKARRYAEIEGALLDHVQTQVVCASLGERDALERGVAAQLDVARRVSDALDARRIPALLPVVGHCALVRAADMPGYAGRRYPRESLLRALLERHGVRAGIHLAGSGAERVIDRCIRIALPIGLDDARLASGLADALAGTAPGATDAPAALPDLLHARAPGAADTADTVDTVDKVDTADTADTADTADTADTADTAAQAGVRRGEAHASRAPMRASDDDAIAIVGMAGRYPGADDLSAFWRNLVDGVNAITEIPAERWDWRAHYHPDPEQAARLRKSYGKWGGFLGEFDCFDPLFFWMAPRRIAMIDPQERLFLEECWKALEDAGYPPSRLGDALRERTGVFGGLSKHGFSLYASQYAGTQPHTSPASMVGRVSHFFDLKGPSVAIDNHCASSLVAVHEACEYLRRGDGDLAIAGGVSLCLHPSSYVQLSLVRMLSRDAHCAAFDEGGAGYVPGEGVGVVVLKRLAQARAHGDPIHAVIRSGAVNHNGRMRYYGQPDQAGQQAAIRAALARARIDPRSISYIEAAASGVETTDAVEMAALTEVFGDRAGAAGAYTIGTVKPAIGHGEAASGMSQLMRVALSLKHATLTPTRLPRRPSPLIDFDRLPFRLAAEAAPWAPVSVDGRPVPRRAGVTAIGNGVNAHLVLEEWPGAPADDSAAAPREPQVFVLSAQDGERLAAYVERWIAFLASGATPDFGRMLRTLQIAREPMPARLALVASDRDDLLRALRAWRDGGASSRVHRGDARRRAGQAALAEQACDPRACAPDEAAAAWVQGRTVRWEALHRGGPWRRVGGLPAYPFARERYRIADAASGAPAGREEASARPD
>NZ_CP004380.1|WP_004549222.1|1556208_1557867_-|halogenase
MSNNQVRKYDVVIIGTGIGGTTLGAILARHGLRVAMIDSGTHPRFAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPSCGVKRNFGFVYHREHTEQNPQEVNQALVVNEVHYFRQDIDAYMLHVAIRYGCDAYQNTVVDDIRIDAGGVTVTTRGGLTFEADFVADGAGYRSVLADKLGLRETPCRAKTHARGLFTHMIDVKPFDACREVPKALQQPVPWHQGTLHHLFDGGWMWVIPFNNTPESKNPLVSVGLMLDPRKHPKPDVRPEQEFADFIAKHPDMARQFADARAVREWVSSGRIQYSASECTGDRFCLLSHATGFIDPLFSRGLFNTMQTTNALAGLLIEAAKDRDFSKARFAPVEKLQQGLIDFNDRLVNCSYLSWGHYPLWNAWFRLWLLTGNYGQLHLQRVMMKYRQTGDARWLEPADALLPGAFTTLEPIMRLFEEAAVCVERYGAGELSGEAAERAIYALLEENAALLPPFFDFVSPAERITWPSTPEKIAALLLEWVERLPEDVRAEYFDYDVRALLQQPVVKDTITADVA
>NZ_CP004380.1|WP_004546727.1|1554683_1556126_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MTSEISGKRRWYALVVLCLGVLMIVLDTTIVNVALPSIAADLRFSENALVWVVNAYMLTFGGCLLLGGRLGDLYGHRRLFLAGVTVFTAASLACGLAQTQLVLIAARAAQGIGGAVVSSVALSLIMTLFVEPGDRAKAMGVYGFVYAGGGSLGVLLGGLLTSALSWHWVFLVNLPLGAVVYLLSSALLPKARAQATRASLDIAGAVTVTAALMLAVYAVVNGNAAGWLSARTLSWLGGAAALFAAFVAIEARVAHPLMPLALCMKRNVAIANLIGILWAAAMFAWFFLAALYLQRVLGYGPLQIGLAFLPANLIMGVFSLIVSALLVVRFGIRVPIAAGLLAAAAGLMLFARAPVGGDFVADVLPGMILLGTGAGIAFNPVLLAAMSGVDPADSGLASGIVNTSFMMGGALGLAVLASVATARTDALLAARTAVPAAMAGGYHAAFMLGAAFAIVAALIGMRLRAAPNPAAMQGLQGATQ
>NZ_CP004380.1|WP_004553366.1|1552142_1554014_+|chloride-channel-protein
MSIAAPHKRDFASNARLPRIALLALAIGVLSTFAAFALLSLIHLFTNLFFFQRFSFAEHSPALNTLGPWAAAVPVAGGIVVGLIARFGSEKIRGHGIPEAIEAILFGKSRMSPKVAVLKPLASGIVIGSGGPFGAEGPIIMTGGAIGSLIAQFVKVTAAERKTLLVAGATAGMTAVFGTPVAAVLLAVELLLFEWRPRSFLPVALACAVAGFARAAFFGVGPLFPVETAAPTAAALGSCALAGLLSGALACGLSVSLYKIEDRFGKLPVHWMWWPAIGGLAVGIGGLIEPRALGVGYDVIGDLLHGHIALQIALAILVVKAVIWVIALGSGTSGGVLAPLLMLGAGLGTLLGPVLPGGEPALWPLVCMAATLGATLGAPLTAIVFAFGLTHDANALLPLLTATLVAHGFATVAMKRSIMTEKIARRGYHIYREYGVDPLERHYVDEVMTRSAVTIDADLSVEVVRARYFGATQAHRAYPVVRDGVLIGMLDRATLDGSPAAHDGDGQADDARAAKMRAADVQMTDMRVADVRVADVLPRRAPLFSLADETCRLVATRLAVHQLERLPVVADPDTMRVVGIVSRSDLVKPALRHFDDEHKRERFRRAHPAAFVKRRFAPARKTG
>NZ_CP004380.1|WP_004524104.1|1551694_1552108_+|MarR-family-transcriptional-regulator
MTKPARELRKTDFEQLSEFRYQMRRFERFSERAAQSEGITPLQYLLLLHIKGYPERDWATVGELAERLQAQHHGVVALVTRCEALGLVRRRPSDADRRQVEVHLQAAGERVLARLAELHRAELKSLRGAFQVPQIDY
>NZ_CP004380.1|WP_004553367.1|1550360_1551554_+|HPP-family-protein
MSSSLAFAHRLARGLVRWLWRFVPIPVTLSRRERVRSCAGALVGIGCVGVTMRALPGRPGDVPLLVAPMGASAVLLFAVPASPLAQPWSLIGGNLVAATVGVACAQWIADPVLAASVAIAGAIGAMFALRCVHPPSGAVALTAVVGGPAVHALGFRFVAEPIALQSAALLGAALVYHALTGHRYPHGGAARPHADSNAHAAAAPLHARFVRADLEAALKNRSEWLDVAPEDLESLLRETELRAYARTFDELSCAEIMSRRPISIAPDTPLPAAMTLLERHRIKALPVVDADARVVGIVTRADLSKAAPYATPGFLRNLSARLPRSLVGPALVARAVMSTRVHTVRTTTPIAELVPLFADHGHHHIPVVDADHQLAGIVTQADLIAGLYRQSQVRLAA
>NZ_CP004380.1|WP_004198341.1|1550035_1550299_+|hypothetical-protein
MGNNGRREAASAAMRGRGRLIDRMRGPWDRLGAGIAGGKLCDSSRSDRANCTPMRAGALARAHFPHPETPTADRAIGGVGNLYHNDI
>NZ_CP004380.1|WP_004198340.1|1549043_1550015_-|LysR-family-transcriptional-regulator
MDMLDNMRLFVRVVEAGSFTAVAKEIDATTAQVSRAVSNLEAHVQTRLLHRTTRHLGLTESGQRYFERAKSILAEIDYANAEARNALLRPSGKLRIHAMTGLGQSHVVSSIVRYQEDNPDVSVELTLAQRMPNLVEEGYDVSIVSASHLPDSGYVAQTCGTSCSVLVASREYLARHGTPTTPDDLAKHVCLRLDTPASPGGEWRLERDDGDETVYALPPAPFQANVPDALSVAVRAGRGIGSIALYTALDDIREGRLVRVLPNYRLDTLSVYAVYATRRYLDAKIRTFLDHLRTTLAPALENDLKELNRLNGGVGKKALREVA
>NZ_CP004380.1|WP_004524106.1|1547446_1548532_+|ionic-transporter-y4hA
MPISSSALPRWTLVAPLAAWLVLALSRVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVGEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQDFQGRGATKALAVLASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLIDGSADESVHAVPPSGRTALTSIAFLFVSLVAVVLLAKLLSPAVERTVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAAVFIWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSITH
>NZ_CP004380.1|WP_004553360.1|1611036_1612269_+|sodium/hydrogen-exchanger
MNSIFVFLSQALLIVAVPPLLMNYLRVGAVVPLVVVQIVFGVVIGPSGLGRLSPETYTALFPPDSLTFLSHVSAIALFFFAIVTGLHLDATGLRGHGRKLGLISTASMLAPMSLGVLAGIAISARYPQALDPHASVAEFVAGIGICCGVTALPVLAAILRETNLTSRRLGQFSLALAAVNDGMLWILLAAFLSVTGANAANGGRLFITSALIVLYFVSILFVVRPLLLVLANRLRTSVDTQILIACAVAVASAAATDRLGLHYLLGAFIAGAIIPGAWRDALLERMQPVTVNVLTPFFFISTGLRVLIDVDAPGFLQITLIITLCTAIGKIAGTTLAARMTGESWGFCLGLGFLAQAKGLMELVVATILLDSHVISRTVFSALILMALISTAFAMPMLRLKPVRGAALSA
>NZ_CP004380.1|WP_004553359.1|1612653_1613838_+|ACP-S-malonyltransferase
MLNTFMFPGQGSQAKGMGGALFDRFADLTAQADAVLGYSIRALCVDDPRDELGRTQFTQPALYVVNALTYYAKCEDSGETPDFLAGHSLGEFNALLAAGCFDFEAGLKLVARRAELMSQARDGAMAAIVNASREQIERTLDEHGLVDTAIANDNTPSQLVISGPAHEIARAEALFQHDRVRYLRLNTSGAFHSKFMRPAQQAFAAHLQSFRLADPAIPVISNVSARPYENGRVSEGLAQQIASPVRWCESIRYLLALAAERGEAIEFTELGHGDVLTRLVHTIRRQTPAPAAAPAAAATSARARPTPPGEPERLAQQTAAAPRASDSASASLGAAERVAAWNRDYPVGTRVRSSLIHDDVLETRTPATVLFGHRAAVYMKGYNGYFDLAEVTPA
>NZ_CP004380.1|WP_004198258.1|1614887_1615121_+|hypothetical-protein
MRREAAWRARPLIPNEPRGPASGRHFSLQEPVLTDDTAAAPPSAFYICAEFFSIIEHSVFYDFLPPHFRLATEKSMM
>NZ_CP004380.1|WP_004528251.1|1615232_1616492_+|hydroxymethylglutaryl-CoA-synthase-family-protein
MTAVGIEALNVYAGVASLDVSRLAEHRKLDMARFQNLLMREKSVALPYEDPITYGVNAAKPIVDALTPDERDRIEMLITCTESAFDFGKSMSTYFHHHLGLKRNCRLFEVKNACYSGVAGLQTAINFILAQVSPGAKALVIATDLSRFIVEEGGEALSADWSFAEPSSGAGAVAMLVSDTPHVFRIDVGANGYYGYEVMDTCRPTTDSEAGNSDLSLLSYLDCCENAFLEYQKRVCDVDYASTFGFLAFHTPFGGMVKGAHRNLMRKASRCSTQEIEQDFQRRAGPGLVYCQRLGNIMGATAMLSVASTIDNGEYRAPQRVGVFSYGSGCCSEFFSGIVDEEGQRRLRGMRIGEQLDRRYALSIDEYEHVLKESRVVRFGTRNAKIDDGFIPAARRAHSRETLFLSRINEYHREYEWIC
>NZ_CP004380.1|WP_004198262.1|1616485_1617256_+|enoyl-CoA-hydratase/isomerase
MLSRPADYRTIRVRYDGDICFLQLHRPDAQNAINNRMIAECMDVLDRCEHAAKIVVLQGLPDVFCFGADFSDIAEKPDALIDSDAIYGLWHRLATGPYITIAHVQGKVNAGGIGFVAASDIAICDENVPFSLSELLFGLIPACVLPFLARRIGTPKAHYMTLMTQPVTAQQAFSWGLVDAIGANTDTLVRKHLLRLRCLNKASVARYKSYAATLDDTLAAARPGAVRVSIEMFADPENRRKIARYVDTGKFPWEAD
>NZ_CP004380.1|WP_004532917.1|1617256_1618039_+|enoyl-CoA-hydratase
MSAHERVVEIREVADCVVQVVMQDRENKNTFSDALIRGLGEAFDAIRQNGRCKAAILTGYGNYFASGGTQESLMYLSEGKGTFAEIAASASRNGANLYSLALNCPVPVIAAMQGHGIGGGFVMGLFADFVVLGKECLYTTNFMKYGFTPGMGATLVLPHKLGLPLAQNMLMTARSFYGDELQKLGVPFPVVPRAEVAACALEIAKNLAEKPRLSLVTLKDHLVAELRSRLPAVIEQELAMHEKTFGQPEVKERIRSLFGQ
>NZ_CP004380.1|WP_004198264.1|1618092_1618332_+|acyl-carrier-protein
MDLQQVFDIIVRHTKEVIPGLDRHAFRTTDALKDLGANSLDRSEIVIMTLESLSLRIPLVEFAGARNIGELAEVLYAKL
>NZ_CP004380.1|WP_004539120.1|1618318_1619563_+|polyketide-beta-ketoacyl:ACP-synthase
MRSSERDEILVTGVGVVSAIGQGRQPFIDALLDGRHAFGVMRRPGRQLPDDAGAGPAPAFFGAEIDSIALPPMLDAHRRTASYSAQAAVACVREAWDDAALGDVDPLRIGLVVGGSNVQQREQALVHDTYRGRYAFLRPSYGLSFMDSDLCGLCTELFGIRGVAFTVGGASASGQLAVLQACRLVESGSVDACIAVGALMDLSYWECQALRSLGAMGSDRFADEPDAACRPFDQDRDGFIYGECSGAIVVERAARMRRAHVSPYAKWLGGCIRMDGTREPAPSLDGEMAVIEGALRDAGIGADSIDYVNPHGSGSTLGDATELDALGRSGLAHARINTTKSLVGHGLSAAGIVELIATLLQMRARRLHPSRNLDQPIDERFDWVRSTCGSDIRRALKLSIGFGGINTALCLERC
>NZ_CP004380.1|WP_004531777.1|1619604_1621284_+|hypothetical-protein
MGDYLAQDARIERITVRDPEARTWFDRGLLWAYGFNFEAAVDCFQEAARIDPDCVLAYWGIAYASGCNYNKQWKVFHPRMIARCMKLARDAIRRAQACRAGASALEMALVRAIECRFQAEGAHDEALLRRWNDDYARAMRDVYLSCPDNLDVAALFADALINRTPWKLWDMSSGKTADGADTDEAIAVLERALAQVDANGLAPHPGLLHVYIHTIEMSPTPEKALRAADALRDLAPDVGHLLHMASHIDILCGHYHDAIVANDRAIAANQRVLDRHPQWLEFRLYCVHDIHFKIYAAMMLGRFSAAWQGVLELEALITEALLRVEQPPMAYLLEGFLSVRVHVLIRFGKWREILEQPFPANAALYCNTTAMLHYARGIAYANLKLAGPAAQARRAFSIAQAALHEHRYVTNNTCADLLKIAACVLDGEIAYHEDRFDEAFAHLRRAVELDDGLEYMEPWGWMMPTRHPLGALLLAQGHVEEAERVYRADLGLDSTIYRSLQHPGNVWSLQGYVSCLRRLGKHETADALQPALDVARARADVEIGVSCFCAAPSKRGCCH
>NZ_CP004380.1|WP_004524091.1|1621449_1622454_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MNGTQRFPMDIPFGWFCIGYSDEVAVGDVKPLRYFGKDLVMFRGESGEIGVLDAYCPHLGAHMGHGGTVEGDSLRCPFHHWAYRKDGFCTSIPYAKEMPLIAKREPIAVPYPVVERNGAIWVWHHPQQIAPTYEVLEHEEFVAPGWSKPVRRFWSFASNPQEIAENGVDTAHFKCIHHMDAMPEGEVSYEGHIRRSRTTGETSMIFPDGVTRTVETGTNVINSGAGQKISRFTGFVTISLMEMATPVEADQVELRFCFAFPECPEGSPEWQGAMNTIDYFSGQLGIEGGDIPIWSHKIHREKPILCDGDGAIMRFRRYFEQFYAPRVVPVTASA

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Crispr_ID: NZ_CP004380_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004380_3

1587149-1587440

Orphan

Consensus_repeat	Method
TGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTGGCCTGC	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_CP004380_3

>merge|NZ_CP004380|3|1587149-1587440|CRISPRCasFinder
GCGGCGGCCCGCGTGGCTTGTGAGGCTTGCGTGGCCTGCGTGGCTTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTGGCCTGCATAGCCTGCATAGCCTGCATAGCCTGCATAGCCTGCATAGCCTGCATAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGGCGACG

>NZ_CP004380|3|3|1587149-1587440|CRISPRCasFinder
GCGGCGGCCCGCGTGGCTTGTGAGGCTTGCGTGGCCTGC	GTGGCTTGCGTAGCCTGCGTAGCC
TGCGTAGCCTGCGTGGCCTGCATAGCCTGCATAGCCTGC	ATAGCCTGCATAGCCTGCATAGCC
TGCATAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGC	GTAGCCTGCGTAGCCTGCGTAGCC
TGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGCCTGC	GTAGCCTGCGTAGCCTGCGTAGCC
TGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTAGGCGACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004380.1\|WP_004528251.1\|1615232_1616492_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NZ_CP004380.1\|WP_004553359.1\|1612653_1613838_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|272922
NZ_CP004380.1\|WP_080340281.1\|1562633_1578665_-\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|237108
NZ_CP004380.1\|WP_004553366.1\|1552142_1554014_+\|chloride-channel-protein	unknown	unknown	gnl\|CDD\|238233
NZ_CP004380.1\|WP_004546727.1\|1554683_1556126_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_CP004380.1\|WP_004524104.1\|1551694_1552108_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_CP004380.1\|WP_004553367.1\|1550360_1551554_+\|HPP-family-protein	unknown	unknown	gnl\|CDD\|225979
NZ_CP004380.1\|WP_004524106.1\|1547446_1548532_+\|ionic-transporter-y4hA	unknown	unknown	gnl\|CDD\|223464
NZ_CP004380.1\|WP_004531777.1\|1619604_1621284_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP004380.1\|WP_004198341.1\|1550035_1550299_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004524091.1\|1621449_1622454_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl\|CDD\|239607
NZ_CP004380.1\|WP_004553360.1\|1611036_1612269_+\|sodium/hydrogen-exchanger	unknown	unknown	gnl\|CDD\|215608
NZ_CP004380.1\|WP_004198264.1\|1618092_1618332_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180851
NZ_CP004380.1\|WP_004551645.1\|1557949_1562650_-\|DUF2156-domain-containing-protein	unknown	unknown	gnl\|CDD\|238429
NZ_CP004380.1\|WP_004198262.1\|1616485_1617256_+\|enoyl-CoA-hydratase/isomerase	unknown	unknown	gnl\|CDD\|235938
NZ_CP004380.1\|WP_004539120.1\|1618318_1619563_+\|polyketide-beta-ketoacyl:ACP-synthase	unknown	unknown	gnl\|CDD\|180839
NZ_CP004380.1\|WP_004198340.1\|1549043_1550015_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP004380.1\|WP_004549222.1\|1556208_1557867_-\|halogenase	unknown	unknown	gnl\|CDD\|223717
NZ_CP004380.1\|WP_004198258.1\|1614887_1615121_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004532917.1\|1617256_1618039_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|235936

Protein	Function_ID	Function_description	E-value
NZ_CP004380.1\|WP_004528251.1\|1615232_1616492_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	7.17071e-102
NZ_CP004380.1\|WP_080340281.1\|1562633_1578665_-\|non-ribosomal-peptide-synthetase	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP004380.1\|WP_004553366.1\|1552142_1554014_+\|chloride-channel-protein	gnl\|CDD\|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	7.50476e-100
NZ_CP004380.1\|WP_004546727.1\|1554683_1556126_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.18813e-61
NZ_CP004380.1\|WP_004553360.1\|1611036_1612269_+\|sodium/hydrogen-exchanger	gnl\|CDD\|215608	PLN03159, PLN03159, cation/H(+) antiporter 15; Provisional.	4.27436e-41
NZ_CP004380.1\|WP_004553367.1\|1550360_1551554_+\|HPP-family-protein	gnl\|CDD\|225979	COG3448, COG3448, CBS-domain-containing membrane protein [Signal transduction mechanisms].	4.83609e-133
NZ_CP004380.1\|WP_004524106.1\|1547446_1548532_+\|ionic-transporter-y4hA	gnl\|CDD\|223464	COG0387, ChaA, Ca2+/H+ antiporter [Inorganic ion transport and metabolism].	2.6957e-73
NZ_CP004380.1\|WP_004531777.1\|1619604_1621284_+\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00218866
NZ_CP004380.1\|WP_004524104.1\|1551694_1552108_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	2.14376e-10
NZ_CP004380.1\|WP_004524091.1\|1621449_1622454_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl\|CDD\|239607	cd03531, Rieske_RO_Alpha_KSH, The alignment model represents the N-terminal rieske iron-sulfur domain of KshA, the oxygenase component of 3-ketosteroid 9-alpha-hydroxylase (KSH). The terminal oxygenase component of KSH is a key enzyme in the microbial steroid degradation pathway, catalyzing the 9 alpha-hydroxylation of 4-androstene-3,17-dione (AD) and 1,4-androstadiene-3,17-dione (ADD). KSH is a two-component class IA monooxygenase, with terminal oxygenase (KshA) and oxygenase reductase (KshB) components. KSH activity has been found in many actino- and proteo- bacterial genera including Rhodococcus, Nocardia, Arthrobacter, Mycobacterium, and Burkholderia.	6.90109e-36
NZ_CP004380.1\|WP_004553359.1\|1612653_1613838_+\|ACP-S-malonyltransferase	gnl\|CDD\|272922	TIGR00128, Malonyl_CoA-acyl_carrier_protein_transacylase, malonyl CoA-acyl carrier protein transacylase. This enzyme of fatty acid biosynthesis transfers the malonyl moeity from coenzyme A to acyl-carrier protein. The seed alignment for this family of proteins contains a single member each from a number of bacterial species but also an additional pair of closely related, uncharacterized proteins from B. subtilis, one of which has a long C-terminal extension. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.08999e-102
NZ_CP004380.1\|WP_004198264.1\|1618092_1618332_+\|acyl-carrier-protein	gnl\|CDD\|180851	PRK07117, PRK07117, acyl carrier protein; Validated.	1.31913e-39
NZ_CP004380.1\|WP_004551645.1\|1557949_1562650_-\|DUF2156-domain-containing-protein	gnl\|CDD\|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	6.63996e-157
NZ_CP004380.1\|WP_004198262.1\|1616485_1617256_+\|enoyl-CoA-hydratase/isomerase	gnl\|CDD\|235938	PRK07112, PRK07112, enoyl-CoA hydratase/isomerase.	4.21258e-167
NZ_CP004380.1\|WP_004539120.1\|1618318_1619563_+\|polyketide-beta-ketoacyl:ACP-synthase	gnl\|CDD\|180839	PRK07103, PRK07103, polyketide beta-ketoacyl:acyl carrier protein synthase; Validated.	0
NZ_CP004380.1\|WP_004198340.1\|1549043_1550015_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.78138e-66
NZ_CP004380.1\|WP_004549222.1\|1556208_1557867_-\|halogenase	gnl\|CDD\|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	2.43201e-19
NZ_CP004380.1\|WP_004532917.1\|1617256_1618039_+\|enoyl-CoA-hydratase	gnl\|CDD\|235936	PRK07110, PRK07110, polyketide biosynthesis enoyl-CoA hydratase; Validated.	9.84342e-151

>NZ_CP004380.1|WP_080340281.1|1562633_1578665_-|non-ribosomal-peptide-synthetase
MNAIISDVIRAYREGKLTTADLASELRRGAGDGAGLPLSEGQRGIWALHALHEDRGAYNVPLCFAVRDLRADAFRRALRFVARQYPSLCAAIRVIDGEPRRVQPAGATLEPIEATLADTLGPDADEAAILAWLREQARQPFSLEDGPLCRVHLLDLAGWRARDAAAASRFGAAHTIVSLHVHHLVLDGQSLLLLIGTLLDAYRALVDGVEPAPRAPAATHDDFVAEERALLDSDEGARRIAYWRRQLDALPPALELPASAPAAAERAAGDAWHAVPLDAARSARVAAFVQSNHLGAAAFFLGMFKLLLHRYTGEPDIVVGMPADARPSQRYRDALGFFVNMLPLRTRLAGETAVVAMLERVQRELVDAMAMQYPFGALVRELGLQGAEDGAPMYRIAFMYQDFLARLRFGDDVEPIGEIRQAGEYELVLEVIEGAAPGGPARFALNWKYDGARYRAAAVEAMARHYLTLLDGVLAAPAARVADCPMLPAAERERLLALGRGPRADHARERRVHDLIDARAQQAPHAIAVSCGGRSLDYARLKADSDALAQRLRACGIGAGDFVAVRLDRSTALVVGLLAVLKAGAAYVPLDPDYPDDWAAQMLGDCRPAAILTRAALAAGAHALARRVAADGPPAVIALDDAADADTHAADGARAAAIAAARQAAASRAHAARAADLAYVIYTSGSTGAPKGVMVTHRALTNFLASMARRPGLHARDTLLAVTTYCFDIAALELFLPLVQGAHCVICDSASARDGGRLRELIDAARPTVMQATPSTWEMLLHAGWRNARRMRVLCGGDTLPDAVKARLLEDGGEVWNLYGPTETTIWSMVAPVTSERPTSIGAPIDNTRIRIVDAYGNPVPIGVPGELCIAGDGLAAGYLNRPDETAARFVDALPDVDGQARERHYRTGDLARWREDGEVEHLGRMDFQVKIRGHRVEVHDIERHLARHPAIRAAAVVARRHAGGDQLVAYYVRGDAAGHGGADDAPALAAELRGHLAGALPDYMIPALFLPIDALPMTHNGKLNRKALASRGIRLRVASSGERRAAPPRAPAAADIEARLLAICREVLKIDDIDRADGFFEVGGNSLSVALIASRVGAEFGLARLGAGAFFRYPTVAALAAHLGARLRGDAGAAEGADGADAGPAGADARASRPAQPRAAGPAARLPAALDDAIAIIGISCQFPGAQDHRAFWRNLRDGKSGARFYSEDELRAAGVPDTLIRDRHYVPMQQTIEGKDLFDRHFFRLTTKDAQLMDPQFRLLLQHAWKAIEDAGCTRERIADAGVYMSASNSYYQAMLRAAGTIDASDEYQAWLLAQGGTIPTRISYELGLTGPSLFIHSNCSSGLVSLSVAAKSLLQRESRCALVGAATVLPDADIGYVYQPGLNLSSDGRCRTFDENADGLTSGEGVAVLLVKRARDAIDDGDPIYALLRGIAVNNDGADKVGFYAPSVGGQADVIRKVLDATGIHPETIGYVEAHGTGTKLGDPVEVAALTDAYRRHTARTGFCAIGSVKPNIGHLDTVAGLSGCIKVALSLRHGEIAPSINYEKPNREIDFAHSPFYVVDRLTRWPAREPGAPRRAALSSFGIGGTNAHLILEAFERDEPPAGMRAPAARAARVIALSARTEERVRAQASQLLAFLEQEAGALPDFDGFAFTLQVGREAMRERVAFVADGYDALAAALARFLRGEPDAAACFTGARGGDSTLAALLDDTGDTGDTAAHGLIAAWCEQGKVAKIAALWAHGVNVDWRRLYGARAPVRVSLPTYPFAPERCEGVARRRAAAPAPRRAGVETAAARLHPLVHDDRSDGARRRFAATYSGEEFFLADHLIRGKRILPGVAYLEMARMAAVRAHGDGALSLHDVVWMTPIVVDGPCEVELSLEAAERAEAEGAAEAAAGVRTMRFNVTSGGGAGARRTNSQGTIRLAPGAAAPAAARVDVAALLARCTREIGAQRFYTFLDSGGGHYGPTFRSVAALHQGEREVLARLALPESVAHADAFVLHPSMMDAAFQIADSLILQPRANGGCLPFFVKELVVRRRPGRDAWVHVRLAGGDATLARYDIDLIDPDGTVCVSMREFSARAETAGGSGRPNTYRAAEWRAAERDGERDGNELSELNELNELNEGNEGNERRRAAPRVAVLDASPRLAHALRGIGVDALWLPADAAHAARGPALRDLDAALHAGAARDLLVLADERRELDDDALRAWLDGAPHAGGARRALVSIAGLADADARAVADIVERERHGRAADVRYDAGGARSVRGFADAAVARWLLDTDALRSGGVYWIAGANGPLGASLACHLATVERATVVLTDAHAIDAARLACLDGYRAGGARLEFIEGDAARDGAALAQRIRARHGRIDGVLHCAQHASAPTLAALAALDRATRADALDCFVACEARDADPDRDPAAALVARFVERRHARVQAGLGGGRTVAIAAHAALPWPDDAPLLRAGGIASQPALAIVQALHHALRSDEAMLAVGWGASAGGVDAGASKAANASNASNASNASNASDASDASNASNASNASNASNASNASNASNASNASNASNTSNTSNTSNTSNTSNAPSVAADLAAPAEPNARIPARARATPDTIAACLKAVIADVIRADVDEIDARQHFGEYGLDSLSLTSVSNRLNDAYRLDASPAGALNPTLFFEYPSVERMAAYLAEHHAARFADASAAPGADGAAECAPRPEAALNAEVEPGNGAAPAPEPEVGFRAGFEPVAPPMPRIEPTASTPPDQPAPQPGGAWHAGRGACPAADDDVAIIGISGRFPGARDVAEFGRNLFDGRDCIGEIPADRWDWRAYLGDPQHEAGKTNSKWGGFIDGIAEFDPLFFSLSPKEAYLLDPAHRLLLMHAWWAIEDAGYNPAALAGSRTALFAGIAQSGYADLRRQAGEGIEGNSFLGVVPSIALNRISHLLDLHGPSEPVETACSSSLVAMHRALVSLRCGDADMALVGGVQTILSPHAHIGFGKAGMLATDGRCKAFSSRADGFVRGEGIGMLFLKRLGDARRDGDAIYGVIRGSAVNHDGRSSSLTAPNPAAQRDVIVQAHMRAGVDPRSIGYIEAHGTGTKLGDPIEINALTQALDTLLRAQREEGAAYVPGACAIGSVKSNIGHLELAAGVSGVIKVLLQMANGRLAKSLHCDELNPYITLDGGPLRVVGANAAWPRPVDRDGREQPRRAGVSSFGIGGVNAHVVLEEYPEADARARDDGQPAAVLLSARDSQRLADYASALLAFVRERREAAAHAPPPRLSDLAYTLQVGREAMRERVGFVVTSLAQLEARLAAFVAGEPAGDGVYRGSVRPARGERAADADGLDRLVDIWLANRKHEALLGAWVKGAAIDWARLHAGGAPRRVHLPGYPFARERYWIAEPAPATGAPGEPAPPRMPTQPHGPTSDGRAESRHPLRRAADGRFLLDLDGDEAFLADHRVDGRRVLPGVAHLEIAYEAARRTFGPADAIRIRNLGWIRPIVADGALRIGVELSVTGAAEGAFRLYTTDPQHGRLTHSEGAIGRADVAQSARALDLGALRDAFATAERVDPAVWYDGFSRAGIDYGPSHRCLETCAVGPAGVLARVRLPAAEARAARPFTLHPGLMDAVLQAAIGLRKRAGGAPRGTPYLPFALDAVEILGGCGEAAWAWLRPSPRDAADASASRGDAGKPAAERIDIDVCDDAGRISVTLRGLTSRPLARRTAPAPEAGNPAGEVGEVADATDADAAEVREISDVSDVSNVSDVAPLADGDVGLLARTAVWSALTPAQWLADPASRPRAGARVFVLGGTAAQRREIARIHPGCEPLEENAADDGGDGADQQAHVDALRRRLAEGAPIDQLVWIAPPEPAADARAGLRGDAIVAAQEHGVLQLFRIVKLLLAAGYGGKPLDWTIVTRETHATSGIDEPSPTHAGVHGFVGSMAKEYRNWRVRLLDMPAREAWPIDAMFSTRFDPRGDALAYRRGRWLARELAAIDALPDGGCHVKTGGVYVVIGGAGGIGEVWSRWMMERYQARIVWIGRRDEDEQIRRKRERLARYGTPPVYLRADASERASLAAARERIAALRWDGRALPTSGVVHSAIVLADASLATMDEARFLAAWRSKADVGVRVAEVFGGDPLDFMLFFSSITSFGKTAGQANYAAGCAFKDAFAAHLGRTLPYPVKVMNWGYWGSVGVVSDETYRRRMASAGFGSIEPDEGMSALERLLASRVGQIAVLKTLRPNLVGDSRADRIRHYPGRDWPDAAPAPATAALQAALAARAGRWHAQASALALGNPELETLIARGLLAGVLPYLDAPGSVDARHARWFDESRAMLHGFGYLARDGAGDAPSWSLTDAGRAAAPHVWQDWERHALAWHDDERRVPMRLAHVCLRALPELLGGKRRATDVMFPGSSMALVEGLYKSNRKADLFNDVVHDAVLSYARALGRALDIVEVGAGTGGTTDGLLRKLVEQGIAVREYRYTDLSHAFLLHAREHYAPRAPFLTTGIFDVDKPIAAQRVPGGRYDVAVATNVLHATRDVRRALRNVKATLRAGGLLILNELSVKSLFSHVTFGLLDGWWMYEDADLRIPGSPGIDSSTWRRVLAEEGFEYVFFPAQGLHAHGQQVIVAQSDGVVRQPRAAAAPGAGAAASPSGGTQAAVPARRAAAASGAPRVEAIPPAAVAPAAFDAATAAPPGTAAAAATAVPADGRSALAHASSPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIEPDASFASYGVDSIMAMALIAALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTVPTEPTASPASSAPPAASPPQPGDAHALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIEPDASFASYGVDSIMAMALIAALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPAASPPQPGDAHALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGEYLLERQGQERACHASNV
>NZ_CP004380.1|WP_004551645.1|1557949_1562650_-|DUF2156-domain-containing-protein
MQATFNPDEVALAGDARRTDGDADRAAASPHGFRFVEKARIADEPGLSARLAARKGDAHQDGVFLDLWPSIFLSDEHGDHIHVLRDRGLLFVTRFVGAPQREAALLSALLDRARGEGRALCYLDMSNRRKPDIERECGLLSTPLGVVQTIDDIRRFTLDGPRMRKLRYLVSKFGRDPSCRVVEYTEPDPAVDGEIRAVMAAWSREKGVVNKVDAILADMRVGNLLKRYRVYLTYLGDRLQNVVVLSHIGEGYITDQEYFVPDMPLGGTEYAYATIIERLAAEGHRKFSLGLTWGLFEPEAGFSDAEGWALVNRTEGQLAQIFRRGVQNHQYKNKYCPAEYPLYLYRSADSRPQIIKQCMGQFFRNGVPYDEIARQIEADDARALAAAGAAPPRATHGGDEAEARSAPGGAPDDARADAPDDASFDAPDGAPIEVSDHAPGSTPPPRAARDERGGERDDGKGGQAGQADRSGKHDPADAHGRAASGTPDAARAPAPADIPDAFFDATQADPNAIRLDLVSDSWAHLGYPFIRERARRLLAGLASPHADPAAPCGLFGVDHCVLTTSGRNAERVFFNLFPAKRKTILQNIPFFSTRHNAAKAGFASVEIPDPRIFDPDCREIFRGGIDFARLREQLEARPDGVAMVLIELCNNASGGYPVPLAQIADVSALCRARGVPFVMDVTRIVRNAELIRRHEPGCANVGLWDTVARIVAHADVVFGSLCKDFGVSAGGIVAANDGRLIGKARRYAEIEGALLDHVQTQVVCASLGERDALERGVAAQLDVARRVSDALDARRIPALLPVVGHCALVRAADMPGYAGRRYPRESLLRALLERHGVRAGIHLAGSGAERVIDRCIRIALPIGLDDARLASGLADALAGTAPGATDAPAALPDLLHARAPGAADTADTVDTVDKVDTADTADTADTADTADTADTAAQAGVRRGEAHASRAPMRASDDDAIAIVGMAGRYPGADDLSAFWRNLVDGVNAITEIPAERWDWRAHYHPDPEQAARLRKSYGKWGGFLGEFDCFDPLFFWMAPRRIAMIDPQERLFLEECWKALEDAGYPPSRLGDALRERTGVFGGLSKHGFSLYASQYAGTQPHTSPASMVGRVSHFFDLKGPSVAIDNHCASSLVAVHEACEYLRRGDGDLAIAGGVSLCLHPSSYVQLSLVRMLSRDAHCAAFDEGGAGYVPGEGVGVVVLKRLAQARAHGDPIHAVIRSGAVNHNGRMRYYGQPDQAGQQAAIRAALARARIDPRSISYIEAAASGVETTDAVEMAALTEVFGDRAGAAGAYTIGTVKPAIGHGEAASGMSQLMRVALSLKHATLTPTRLPRRPSPLIDFDRLPFRLAAEAAPWAPVSVDGRPVPRRAGVTAIGNGVNAHLVLEEWPGAPADDSAAAPREPQVFVLSAQDGERLAAYVERWIAFLASGATPDFGRMLRTLQIAREPMPARLALVASDRDDLLRALRAWRDGGASSRVHRGDARRRAGQAALAEQACDPRACAPDEAAAAWVQGRTVRWEALHRGGPWRRVGGLPAYPFARERYRIADAASGAPAGREEASARPD
>NZ_CP004380.1|WP_004549222.1|1556208_1557867_-|halogenase
MSNNQVRKYDVVIIGTGIGGTTLGAILARHGLRVAMIDSGTHPRFAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPSCGVKRNFGFVYHREHTEQNPQEVNQALVVNEVHYFRQDIDAYMLHVAIRYGCDAYQNTVVDDIRIDAGGVTVTTRGGLTFEADFVADGAGYRSVLADKLGLRETPCRAKTHARGLFTHMIDVKPFDACREVPKALQQPVPWHQGTLHHLFDGGWMWVIPFNNTPESKNPLVSVGLMLDPRKHPKPDVRPEQEFADFIAKHPDMARQFADARAVREWVSSGRIQYSASECTGDRFCLLSHATGFIDPLFSRGLFNTMQTTNALAGLLIEAAKDRDFSKARFAPVEKLQQGLIDFNDRLVNCSYLSWGHYPLWNAWFRLWLLTGNYGQLHLQRVMMKYRQTGDARWLEPADALLPGAFTTLEPIMRLFEEAAVCVERYGAGELSGEAAERAIYALLEENAALLPPFFDFVSPAERITWPSTPEKIAALLLEWVERLPEDVRAEYFDYDVRALLQQPVVKDTITADVA
>NZ_CP004380.1|WP_004546727.1|1554683_1556126_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MTSEISGKRRWYALVVLCLGVLMIVLDTTIVNVALPSIAADLRFSENALVWVVNAYMLTFGGCLLLGGRLGDLYGHRRLFLAGVTVFTAASLACGLAQTQLVLIAARAAQGIGGAVVSSVALSLIMTLFVEPGDRAKAMGVYGFVYAGGGSLGVLLGGLLTSALSWHWVFLVNLPLGAVVYLLSSALLPKARAQATRASLDIAGAVTVTAALMLAVYAVVNGNAAGWLSARTLSWLGGAAALFAAFVAIEARVAHPLMPLALCMKRNVAIANLIGILWAAAMFAWFFLAALYLQRVLGYGPLQIGLAFLPANLIMGVFSLIVSALLVVRFGIRVPIAAGLLAAAAGLMLFARAPVGGDFVADVLPGMILLGTGAGIAFNPVLLAAMSGVDPADSGLASGIVNTSFMMGGALGLAVLASVATARTDALLAARTAVPAAMAGGYHAAFMLGAAFAIVAALIGMRLRAAPNPAAMQGLQGATQ
>NZ_CP004380.1|WP_004553366.1|1552142_1554014_+|chloride-channel-protein
MSIAAPHKRDFASNARLPRIALLALAIGVLSTFAAFALLSLIHLFTNLFFFQRFSFAEHSPALNTLGPWAAAVPVAGGIVVGLIARFGSEKIRGHGIPEAIEAILFGKSRMSPKVAVLKPLASGIVIGSGGPFGAEGPIIMTGGAIGSLIAQFVKVTAAERKTLLVAGATAGMTAVFGTPVAAVLLAVELLLFEWRPRSFLPVALACAVAGFARAAFFGVGPLFPVETAAPTAAALGSCALAGLLSGALACGLSVSLYKIEDRFGKLPVHWMWWPAIGGLAVGIGGLIEPRALGVGYDVIGDLLHGHIALQIALAILVVKAVIWVIALGSGTSGGVLAPLLMLGAGLGTLLGPVLPGGEPALWPLVCMAATLGATLGAPLTAIVFAFGLTHDANALLPLLTATLVAHGFATVAMKRSIMTEKIARRGYHIYREYGVDPLERHYVDEVMTRSAVTIDADLSVEVVRARYFGATQAHRAYPVVRDGVLIGMLDRATLDGSPAAHDGDGQADDARAAKMRAADVQMTDMRVADVRVADVLPRRAPLFSLADETCRLVATRLAVHQLERLPVVADPDTMRVVGIVSRSDLVKPALRHFDDEHKRERFRRAHPAAFVKRRFAPARKTG
>NZ_CP004380.1|WP_004524104.1|1551694_1552108_+|MarR-family-transcriptional-regulator
MTKPARELRKTDFEQLSEFRYQMRRFERFSERAAQSEGITPLQYLLLLHIKGYPERDWATVGELAERLQAQHHGVVALVTRCEALGLVRRRPSDADRRQVEVHLQAAGERVLARLAELHRAELKSLRGAFQVPQIDY
>NZ_CP004380.1|WP_004553367.1|1550360_1551554_+|HPP-family-protein
MSSSLAFAHRLARGLVRWLWRFVPIPVTLSRRERVRSCAGALVGIGCVGVTMRALPGRPGDVPLLVAPMGASAVLLFAVPASPLAQPWSLIGGNLVAATVGVACAQWIADPVLAASVAIAGAIGAMFALRCVHPPSGAVALTAVVGGPAVHALGFRFVAEPIALQSAALLGAALVYHALTGHRYPHGGAARPHADSNAHAAAAPLHARFVRADLEAALKNRSEWLDVAPEDLESLLRETELRAYARTFDELSCAEIMSRRPISIAPDTPLPAAMTLLERHRIKALPVVDADARVVGIVTRADLSKAAPYATPGFLRNLSARLPRSLVGPALVARAVMSTRVHTVRTTTPIAELVPLFADHGHHHIPVVDADHQLAGIVTQADLIAGLYRQSQVRLAA
>NZ_CP004380.1|WP_004198341.1|1550035_1550299_+|hypothetical-protein
MGNNGRREAASAAMRGRGRLIDRMRGPWDRLGAGIAGGKLCDSSRSDRANCTPMRAGALARAHFPHPETPTADRAIGGVGNLYHNDI
>NZ_CP004380.1|WP_004198340.1|1549043_1550015_-|LysR-family-transcriptional-regulator
MDMLDNMRLFVRVVEAGSFTAVAKEIDATTAQVSRAVSNLEAHVQTRLLHRTTRHLGLTESGQRYFERAKSILAEIDYANAEARNALLRPSGKLRIHAMTGLGQSHVVSSIVRYQEDNPDVSVELTLAQRMPNLVEEGYDVSIVSASHLPDSGYVAQTCGTSCSVLVASREYLARHGTPTTPDDLAKHVCLRLDTPASPGGEWRLERDDGDETVYALPPAPFQANVPDALSVAVRAGRGIGSIALYTALDDIREGRLVRVLPNYRLDTLSVYAVYATRRYLDAKIRTFLDHLRTTLAPALENDLKELNRLNGGVGKKALREVA
>NZ_CP004380.1|WP_004524106.1|1547446_1548532_+|ionic-transporter-y4hA
MPISSSALPRWTLVAPLAAWLVLALSRVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVGEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQDFQGRGATKALAVLASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLIDGSADESVHAVPPSGRTALTSIAFLFVSLVAVVLLAKLLSPAVERTVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAAVFIWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSITH
>NZ_CP004380.1|WP_004553360.1|1611036_1612269_+|sodium/hydrogen-exchanger
MNSIFVFLSQALLIVAVPPLLMNYLRVGAVVPLVVVQIVFGVVIGPSGLGRLSPETYTALFPPDSLTFLSHVSAIALFFFAIVTGLHLDATGLRGHGRKLGLISTASMLAPMSLGVLAGIAISARYPQALDPHASVAEFVAGIGICCGVTALPVLAAILRETNLTSRRLGQFSLALAAVNDGMLWILLAAFLSVTGANAANGGRLFITSALIVLYFVSILFVVRPLLLVLANRLRTSVDTQILIACAVAVASAAATDRLGLHYLLGAFIAGAIIPGAWRDALLERMQPVTVNVLTPFFFISTGLRVLIDVDAPGFLQITLIITLCTAIGKIAGTTLAARMTGESWGFCLGLGFLAQAKGLMELVVATILLDSHVISRTVFSALILMALISTAFAMPMLRLKPVRGAALSA
>NZ_CP004380.1|WP_004553359.1|1612653_1613838_+|ACP-S-malonyltransferase
MLNTFMFPGQGSQAKGMGGALFDRFADLTAQADAVLGYSIRALCVDDPRDELGRTQFTQPALYVVNALTYYAKCEDSGETPDFLAGHSLGEFNALLAAGCFDFEAGLKLVARRAELMSQARDGAMAAIVNASREQIERTLDEHGLVDTAIANDNTPSQLVISGPAHEIARAEALFQHDRVRYLRLNTSGAFHSKFMRPAQQAFAAHLQSFRLADPAIPVISNVSARPYENGRVSEGLAQQIASPVRWCESIRYLLALAAERGEAIEFTELGHGDVLTRLVHTIRRQTPAPAAAPAAAATSARARPTPPGEPERLAQQTAAAPRASDSASASLGAAERVAAWNRDYPVGTRVRSSLIHDDVLETRTPATVLFGHRAAVYMKGYNGYFDLAEVTPA
>NZ_CP004380.1|WP_004198258.1|1614887_1615121_+|hypothetical-protein
MRREAAWRARPLIPNEPRGPASGRHFSLQEPVLTDDTAAAPPSAFYICAEFFSIIEHSVFYDFLPPHFRLATEKSMM
>NZ_CP004380.1|WP_004528251.1|1615232_1616492_+|hydroxymethylglutaryl-CoA-synthase-family-protein
MTAVGIEALNVYAGVASLDVSRLAEHRKLDMARFQNLLMREKSVALPYEDPITYGVNAAKPIVDALTPDERDRIEMLITCTESAFDFGKSMSTYFHHHLGLKRNCRLFEVKNACYSGVAGLQTAINFILAQVSPGAKALVIATDLSRFIVEEGGEALSADWSFAEPSSGAGAVAMLVSDTPHVFRIDVGANGYYGYEVMDTCRPTTDSEAGNSDLSLLSYLDCCENAFLEYQKRVCDVDYASTFGFLAFHTPFGGMVKGAHRNLMRKASRCSTQEIEQDFQRRAGPGLVYCQRLGNIMGATAMLSVASTIDNGEYRAPQRVGVFSYGSGCCSEFFSGIVDEEGQRRLRGMRIGEQLDRRYALSIDEYEHVLKESRVVRFGTRNAKIDDGFIPAARRAHSRETLFLSRINEYHREYEWIC
>NZ_CP004380.1|WP_004198262.1|1616485_1617256_+|enoyl-CoA-hydratase/isomerase
MLSRPADYRTIRVRYDGDICFLQLHRPDAQNAINNRMIAECMDVLDRCEHAAKIVVLQGLPDVFCFGADFSDIAEKPDALIDSDAIYGLWHRLATGPYITIAHVQGKVNAGGIGFVAASDIAICDENVPFSLSELLFGLIPACVLPFLARRIGTPKAHYMTLMTQPVTAQQAFSWGLVDAIGANTDTLVRKHLLRLRCLNKASVARYKSYAATLDDTLAAARPGAVRVSIEMFADPENRRKIARYVDTGKFPWEAD
>NZ_CP004380.1|WP_004532917.1|1617256_1618039_+|enoyl-CoA-hydratase
MSAHERVVEIREVADCVVQVVMQDRENKNTFSDALIRGLGEAFDAIRQNGRCKAAILTGYGNYFASGGTQESLMYLSEGKGTFAEIAASASRNGANLYSLALNCPVPVIAAMQGHGIGGGFVMGLFADFVVLGKECLYTTNFMKYGFTPGMGATLVLPHKLGLPLAQNMLMTARSFYGDELQKLGVPFPVVPRAEVAACALEIAKNLAEKPRLSLVTLKDHLVAELRSRLPAVIEQELAMHEKTFGQPEVKERIRSLFGQ
>NZ_CP004380.1|WP_004198264.1|1618092_1618332_+|acyl-carrier-protein
MDLQQVFDIIVRHTKEVIPGLDRHAFRTTDALKDLGANSLDRSEIVIMTLESLSLRIPLVEFAGARNIGELAEVLYAKL
>NZ_CP004380.1|WP_004539120.1|1618318_1619563_+|polyketide-beta-ketoacyl:ACP-synthase
MRSSERDEILVTGVGVVSAIGQGRQPFIDALLDGRHAFGVMRRPGRQLPDDAGAGPAPAFFGAEIDSIALPPMLDAHRRTASYSAQAAVACVREAWDDAALGDVDPLRIGLVVGGSNVQQREQALVHDTYRGRYAFLRPSYGLSFMDSDLCGLCTELFGIRGVAFTVGGASASGQLAVLQACRLVESGSVDACIAVGALMDLSYWECQALRSLGAMGSDRFADEPDAACRPFDQDRDGFIYGECSGAIVVERAARMRRAHVSPYAKWLGGCIRMDGTREPAPSLDGEMAVIEGALRDAGIGADSIDYVNPHGSGSTLGDATELDALGRSGLAHARINTTKSLVGHGLSAAGIVELIATLLQMRARRLHPSRNLDQPIDERFDWVRSTCGSDIRRALKLSIGFGGINTALCLERC
>NZ_CP004380.1|WP_004531777.1|1619604_1621284_+|hypothetical-protein
MGDYLAQDARIERITVRDPEARTWFDRGLLWAYGFNFEAAVDCFQEAARIDPDCVLAYWGIAYASGCNYNKQWKVFHPRMIARCMKLARDAIRRAQACRAGASALEMALVRAIECRFQAEGAHDEALLRRWNDDYARAMRDVYLSCPDNLDVAALFADALINRTPWKLWDMSSGKTADGADTDEAIAVLERALAQVDANGLAPHPGLLHVYIHTIEMSPTPEKALRAADALRDLAPDVGHLLHMASHIDILCGHYHDAIVANDRAIAANQRVLDRHPQWLEFRLYCVHDIHFKIYAAMMLGRFSAAWQGVLELEALITEALLRVEQPPMAYLLEGFLSVRVHVLIRFGKWREILEQPFPANAALYCNTTAMLHYARGIAYANLKLAGPAAQARRAFSIAQAALHEHRYVTNNTCADLLKIAACVLDGEIAYHEDRFDEAFAHLRRAVELDDGLEYMEPWGWMMPTRHPLGALLLAQGHVEEAERVYRADLGLDSTIYRSLQHPGNVWSLQGYVSCLRRLGKHETADALQPALDVARARADVEIGVSCFCAAPSKRGCCH
>NZ_CP004380.1|WP_004524091.1|1621449_1622454_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MNGTQRFPMDIPFGWFCIGYSDEVAVGDVKPLRYFGKDLVMFRGESGEIGVLDAYCPHLGAHMGHGGTVEGDSLRCPFHHWAYRKDGFCTSIPYAKEMPLIAKREPIAVPYPVVERNGAIWVWHHPQQIAPTYEVLEHEEFVAPGWSKPVRRFWSFASNPQEIAENGVDTAHFKCIHHMDAMPEGEVSYEGHIRRSRTTGETSMIFPDGVTRTVETGTNVINSGAGQKISRFTGFVTISLMEMATPVEADQVELRFCFAFPECPEGSPEWQGAMNTIDYFSGQLGIEGGDIPIWSHKIHREKPILCDGDGAIMRFRRYFEQFYAPRVVPVTASA

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Crispr_ID: NZ_CP004380_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004380_4

1588073-1588246

Orphan

Consensus_repeat	Method
TGCGTAGCCTGCGTAGCCTGCGTAGCCTGCGTGGCCTGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP004380_4

>merge|NZ_CP004380|4|1588073-1588246|CRISPRCasFinder
AGCGCGTCCTGCATGTCCTGCATGTCCTGCGTGTCATGCATGTCCTGCGTGTCGTGCATGTCATGCATGTCATGCATGTCGTGCGTGTCGTGCGTGTCGTGCGTGTCGTGCGTGTCGTGCGTGTCGTGCGTGTCGTGCGTGTCGTGCGTGTCGTGCGTGTCGTGCATGTCGTGC

>NZ_CP004380|4|4|1588073-1588246|CRISPRCasFinder
AGCGCGTCCTGCATGTCCTGCATGTCCTGCGTGTCATGC	ATGTCCTGCGTGTCGTGCATGTCATGCATGTCA
TGCATGTCGTGCGTGTCGTGCGTGTCGTGCGTGTCGTGC	GTGTCGTGCGTGTCGTGCGTGTCG
TGCGTGTCGTGCGTGTCGTGCGTGTCGTGCATGTCGTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004380.1\|WP_004528251.1\|1615232_1616492_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NZ_CP004380.1\|WP_004553359.1\|1612653_1613838_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|272922
NZ_CP004380.1\|WP_080340281.1\|1562633_1578665_-\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|237108
NZ_CP004380.1\|WP_004553366.1\|1552142_1554014_+\|chloride-channel-protein	unknown	unknown	gnl\|CDD\|238233
NZ_CP004380.1\|WP_004546727.1\|1554683_1556126_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_CP004380.1\|WP_004524104.1\|1551694_1552108_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_CP004380.1\|WP_004553367.1\|1550360_1551554_+\|HPP-family-protein	unknown	unknown	gnl\|CDD\|225979
NZ_CP004380.1\|WP_004524106.1\|1547446_1548532_+\|ionic-transporter-y4hA	unknown	unknown	gnl\|CDD\|223464
NZ_CP004380.1\|WP_004531777.1\|1619604_1621284_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP004380.1\|WP_004198341.1\|1550035_1550299_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004524091.1\|1621449_1622454_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl\|CDD\|239607
NZ_CP004380.1\|WP_004553360.1\|1611036_1612269_+\|sodium/hydrogen-exchanger	unknown	unknown	gnl\|CDD\|215608
NZ_CP004380.1\|WP_004198264.1\|1618092_1618332_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180851
NZ_CP004380.1\|WP_004551645.1\|1557949_1562650_-\|DUF2156-domain-containing-protein	unknown	unknown	gnl\|CDD\|238429
NZ_CP004380.1\|WP_004198262.1\|1616485_1617256_+\|enoyl-CoA-hydratase/isomerase	unknown	unknown	gnl\|CDD\|235938
NZ_CP004380.1\|WP_004539120.1\|1618318_1619563_+\|polyketide-beta-ketoacyl:ACP-synthase	unknown	unknown	gnl\|CDD\|180839
NZ_CP004380.1\|WP_004198340.1\|1549043_1550015_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP004380.1\|WP_004549222.1\|1556208_1557867_-\|halogenase	unknown	unknown	gnl\|CDD\|223717
NZ_CP004380.1\|WP_004198258.1\|1614887_1615121_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004380.1\|WP_004532917.1\|1617256_1618039_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|235936

Protein	Function_ID	Function_description	E-value
NZ_CP004380.1\|WP_004528251.1\|1615232_1616492_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	7.17071e-102
NZ_CP004380.1\|WP_080340281.1\|1562633_1578665_-\|non-ribosomal-peptide-synthetase	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP004380.1\|WP_004553366.1\|1552142_1554014_+\|chloride-channel-protein	gnl\|CDD\|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	7.50476e-100
NZ_CP004380.1\|WP_004546727.1\|1554683_1556126_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.18813e-61
NZ_CP004380.1\|WP_004553360.1\|1611036_1612269_+\|sodium/hydrogen-exchanger	gnl\|CDD\|215608	PLN03159, PLN03159, cation/H(+) antiporter 15; Provisional.	4.27436e-41
NZ_CP004380.1\|WP_004553367.1\|1550360_1551554_+\|HPP-family-protein	gnl\|CDD\|225979	COG3448, COG3448, CBS-domain-containing membrane protein [Signal transduction mechanisms].	4.83609e-133
NZ_CP004380.1\|WP_004524106.1\|1547446_1548532_+\|ionic-transporter-y4hA	gnl\|CDD\|223464	COG0387, ChaA, Ca2+/H+ antiporter [Inorganic ion transport and metabolism].	2.6957e-73
NZ_CP004380.1\|WP_004531777.1\|1619604_1621284_+\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00218866
NZ_CP004380.1\|WP_004524104.1\|1551694_1552108_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	2.14376e-10
NZ_CP004380.1\|WP_004524091.1\|1621449_1622454_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl\|CDD\|239607	cd03531, Rieske_RO_Alpha_KSH, The alignment model represents the N-terminal rieske iron-sulfur domain of KshA, the oxygenase component of 3-ketosteroid 9-alpha-hydroxylase (KSH). The terminal oxygenase component of KSH is a key enzyme in the microbial steroid degradation pathway, catalyzing the 9 alpha-hydroxylation of 4-androstene-3,17-dione (AD) and 1,4-androstadiene-3,17-dione (ADD). KSH is a two-component class IA monooxygenase, with terminal oxygenase (KshA) and oxygenase reductase (KshB) components. KSH activity has been found in many actino- and proteo- bacterial genera including Rhodococcus, Nocardia, Arthrobacter, Mycobacterium, and Burkholderia.	6.90109e-36
NZ_CP004380.1\|WP_004553359.1\|1612653_1613838_+\|ACP-S-malonyltransferase	gnl\|CDD\|272922	TIGR00128, Malonyl_CoA-acyl_carrier_protein_transacylase, malonyl CoA-acyl carrier protein transacylase. This enzyme of fatty acid biosynthesis transfers the malonyl moeity from coenzyme A to acyl-carrier protein. The seed alignment for this family of proteins contains a single member each from a number of bacterial species but also an additional pair of closely related, uncharacterized proteins from B. subtilis, one of which has a long C-terminal extension. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.08999e-102
NZ_CP004380.1\|WP_004198264.1\|1618092_1618332_+\|acyl-carrier-protein	gnl\|CDD\|180851	PRK07117, PRK07117, acyl carrier protein; Validated.	1.31913e-39
NZ_CP004380.1\|WP_004551645.1\|1557949_1562650_-\|DUF2156-domain-containing-protein	gnl\|CDD\|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	6.63996e-157
NZ_CP004380.1\|WP_004198262.1\|1616485_1617256_+\|enoyl-CoA-hydratase/isomerase	gnl\|CDD\|235938	PRK07112, PRK07112, enoyl-CoA hydratase/isomerase.	4.21258e-167
NZ_CP004380.1\|WP_004539120.1\|1618318_1619563_+\|polyketide-beta-ketoacyl:ACP-synthase	gnl\|CDD\|180839	PRK07103, PRK07103, polyketide beta-ketoacyl:acyl carrier protein synthase; Validated.	0
NZ_CP004380.1\|WP_004198340.1\|1549043_1550015_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.78138e-66
NZ_CP004380.1\|WP_004549222.1\|1556208_1557867_-\|halogenase	gnl\|CDD\|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	2.43201e-19
NZ_CP004380.1\|WP_004532917.1\|1617256_1618039_+\|enoyl-CoA-hydratase	gnl\|CDD\|235936	PRK07110, PRK07110, polyketide biosynthesis enoyl-CoA hydratase; Validated.	9.84342e-151

>NZ_CP004380.1|WP_080340281.1|1562633_1578665_-|non-ribosomal-peptide-synthetase
MNAIISDVIRAYREGKLTTADLASELRRGAGDGAGLPLSEGQRGIWALHALHEDRGAYNVPLCFAVRDLRADAFRRALRFVARQYPSLCAAIRVIDGEPRRVQPAGATLEPIEATLADTLGPDADEAAILAWLREQARQPFSLEDGPLCRVHLLDLAGWRARDAAAASRFGAAHTIVSLHVHHLVLDGQSLLLLIGTLLDAYRALVDGVEPAPRAPAATHDDFVAEERALLDSDEGARRIAYWRRQLDALPPALELPASAPAAAERAAGDAWHAVPLDAARSARVAAFVQSNHLGAAAFFLGMFKLLLHRYTGEPDIVVGMPADARPSQRYRDALGFFVNMLPLRTRLAGETAVVAMLERVQRELVDAMAMQYPFGALVRELGLQGAEDGAPMYRIAFMYQDFLARLRFGDDVEPIGEIRQAGEYELVLEVIEGAAPGGPARFALNWKYDGARYRAAAVEAMARHYLTLLDGVLAAPAARVADCPMLPAAERERLLALGRGPRADHARERRVHDLIDARAQQAPHAIAVSCGGRSLDYARLKADSDALAQRLRACGIGAGDFVAVRLDRSTALVVGLLAVLKAGAAYVPLDPDYPDDWAAQMLGDCRPAAILTRAALAAGAHALARRVAADGPPAVIALDDAADADTHAADGARAAAIAAARQAAASRAHAARAADLAYVIYTSGSTGAPKGVMVTHRALTNFLASMARRPGLHARDTLLAVTTYCFDIAALELFLPLVQGAHCVICDSASARDGGRLRELIDAARPTVMQATPSTWEMLLHAGWRNARRMRVLCGGDTLPDAVKARLLEDGGEVWNLYGPTETTIWSMVAPVTSERPTSIGAPIDNTRIRIVDAYGNPVPIGVPGELCIAGDGLAAGYLNRPDETAARFVDALPDVDGQARERHYRTGDLARWREDGEVEHLGRMDFQVKIRGHRVEVHDIERHLARHPAIRAAAVVARRHAGGDQLVAYYVRGDAAGHGGADDAPALAAELRGHLAGALPDYMIPALFLPIDALPMTHNGKLNRKALASRGIRLRVASSGERRAAPPRAPAAADIEARLLAICREVLKIDDIDRADGFFEVGGNSLSVALIASRVGAEFGLARLGAGAFFRYPTVAALAAHLGARLRGDAGAAEGADGADAGPAGADARASRPAQPRAAGPAARLPAALDDAIAIIGISCQFPGAQDHRAFWRNLRDGKSGARFYSEDELRAAGVPDTLIRDRHYVPMQQTIEGKDLFDRHFFRLTTKDAQLMDPQFRLLLQHAWKAIEDAGCTRERIADAGVYMSASNSYYQAMLRAAGTIDASDEYQAWLLAQGGTIPTRISYELGLTGPSLFIHSNCSSGLVSLSVAAKSLLQRESRCALVGAATVLPDADIGYVYQPGLNLSSDGRCRTFDENADGLTSGEGVAVLLVKRARDAIDDGDPIYALLRGIAVNNDGADKVGFYAPSVGGQADVIRKVLDATGIHPETIGYVEAHGTGTKLGDPVEVAALTDAYRRHTARTGFCAIGSVKPNIGHLDTVAGLSGCIKVALSLRHGEIAPSINYEKPNREIDFAHSPFYVVDRLTRWPAREPGAPRRAALSSFGIGGTNAHLILEAFERDEPPAGMRAPAARAARVIALSARTEERVRAQASQLLAFLEQEAGALPDFDGFAFTLQVGREAMRERVAFVADGYDALAAALARFLRGEPDAAACFTGARGGDSTLAALLDDTGDTGDTAAHGLIAAWCEQGKVAKIAALWAHGVNVDWRRLYGARAPVRVSLPTYPFAPERCEGVARRRAAAPAPRRAGVETAAARLHPLVHDDRSDGARRRFAATYSGEEFFLADHLIRGKRILPGVAYLEMARMAAVRAHGDGALSLHDVVWMTPIVVDGPCEVELSLEAAERAEAEGAAEAAAGVRTMRFNVTSGGGAGARRTNSQGTIRLAPGAAAPAAARVDVAALLARCTREIGAQRFYTFLDSGGGHYGPTFRSVAALHQGEREVLARLALPESVAHADAFVLHPSMMDAAFQIADSLILQPRANGGCLPFFVKELVVRRRPGRDAWVHVRLAGGDATLARYDIDLIDPDGTVCVSMREFSARAETAGGSGRPNTYRAAEWRAAERDGERDGNELSELNELNELNEGNEGNERRRAAPRVAVLDASPRLAHALRGIGVDALWLPADAAHAARGPALRDLDAALHAGAARDLLVLADERRELDDDALRAWLDGAPHAGGARRALVSIAGLADADARAVADIVERERHGRAADVRYDAGGARSVRGFADAAVARWLLDTDALRSGGVYWIAGANGPLGASLACHLATVERATVVLTDAHAIDAARLACLDGYRAGGARLEFIEGDAARDGAALAQRIRARHGRIDGVLHCAQHASAPTLAALAALDRATRADALDCFVACEARDADPDRDPAAALVARFVERRHARVQAGLGGGRTVAIAAHAALPWPDDAPLLRAGGIASQPALAIVQALHHALRSDEAMLAVGWGASAGGVDAGASKAANASNASNASNASNASDASDASNASNASNASNASNASNASNASNASNASNASNTSNTSNTSNTSNTSNAPSVAADLAAPAEPNARIPARARATPDTIAACLKAVIADVIRADVDEIDARQHFGEYGLDSLSLTSVSNRLNDAYRLDASPAGALNPTLFFEYPSVERMAAYLAEHHAARFADASAAPGADGAAECAPRPEAALNAEVEPGNGAAPAPEPEVGFRAGFEPVAPPMPRIEPTASTPPDQPAPQPGGAWHAGRGACPAADDDVAIIGISGRFPGARDVAEFGRNLFDGRDCIGEIPADRWDWRAYLGDPQHEAGKTNSKWGGFIDGIAEFDPLFFSLSPKEAYLLDPAHRLLLMHAWWAIEDAGYNPAALAGSRTALFAGIAQSGYADLRRQAGEGIEGNSFLGVVPSIALNRISHLLDLHGPSEPVETACSSSLVAMHRALVSLRCGDADMALVGGVQTILSPHAHIGFGKAGMLATDGRCKAFSSRADGFVRGEGIGMLFLKRLGDARRDGDAIYGVIRGSAVNHDGRSSSLTAPNPAAQRDVIVQAHMRAGVDPRSIGYIEAHGTGTKLGDPIEINALTQALDTLLRAQREEGAAYVPGACAIGSVKSNIGHLELAAGVSGVIKVLLQMANGRLAKSLHCDELNPYITLDGGPLRVVGANAAWPRPVDRDGREQPRRAGVSSFGIGGVNAHVVLEEYPEADARARDDGQPAAVLLSARDSQRLADYASALLAFVRERREAAAHAPPPRLSDLAYTLQVGREAMRERVGFVVTSLAQLEARLAAFVAGEPAGDGVYRGSVRPARGERAADADGLDRLVDIWLANRKHEALLGAWVKGAAIDWARLHAGGAPRRVHLPGYPFARERYWIAEPAPATGAPGEPAPPRMPTQPHGPTSDGRAESRHPLRRAADGRFLLDLDGDEAFLADHRVDGRRVLPGVAHLEIAYEAARRTFGPADAIRIRNLGWIRPIVADGALRIGVELSVTGAAEGAFRLYTTDPQHGRLTHSEGAIGRADVAQSARALDLGALRDAFATAERVDPAVWYDGFSRAGIDYGPSHRCLETCAVGPAGVLARVRLPAAEARAARPFTLHPGLMDAVLQAAIGLRKRAGGAPRGTPYLPFALDAVEILGGCGEAAWAWLRPSPRDAADASASRGDAGKPAAERIDIDVCDDAGRISVTLRGLTSRPLARRTAPAPEAGNPAGEVGEVADATDADAAEVREISDVSDVSNVSDVAPLADGDVGLLARTAVWSALTPAQWLADPASRPRAGARVFVLGGTAAQRREIARIHPGCEPLEENAADDGGDGADQQAHVDALRRRLAEGAPIDQLVWIAPPEPAADARAGLRGDAIVAAQEHGVLQLFRIVKLLLAAGYGGKPLDWTIVTRETHATSGIDEPSPTHAGVHGFVGSMAKEYRNWRVRLLDMPAREAWPIDAMFSTRFDPRGDALAYRRGRWLARELAAIDALPDGGCHVKTGGVYVVIGGAGGIGEVWSRWMMERYQARIVWIGRRDEDEQIRRKRERLARYGTPPVYLRADASERASLAAARERIAALRWDGRALPTSGVVHSAIVLADASLATMDEARFLAAWRSKADVGVRVAEVFGGDPLDFMLFFSSITSFGKTAGQANYAAGCAFKDAFAAHLGRTLPYPVKVMNWGYWGSVGVVSDETYRRRMASAGFGSIEPDEGMSALERLLASRVGQIAVLKTLRPNLVGDSRADRIRHYPGRDWPDAAPAPATAALQAALAARAGRWHAQASALALGNPELETLIARGLLAGVLPYLDAPGSVDARHARWFDESRAMLHGFGYLARDGAGDAPSWSLTDAGRAAAPHVWQDWERHALAWHDDERRVPMRLAHVCLRALPELLGGKRRATDVMFPGSSMALVEGLYKSNRKADLFNDVVHDAVLSYARALGRALDIVEVGAGTGGTTDGLLRKLVEQGIAVREYRYTDLSHAFLLHAREHYAPRAPFLTTGIFDVDKPIAAQRVPGGRYDVAVATNVLHATRDVRRALRNVKATLRAGGLLILNELSVKSLFSHVTFGLLDGWWMYEDADLRIPGSPGIDSSTWRRVLAEEGFEYVFFPAQGLHAHGQQVIVAQSDGVVRQPRAAAAPGAGAAASPSGGTQAAVPARRAAAASGAPRVEAIPPAAVAPAAFDAATAAPPGTAAAAATAVPADGRSALAHASSPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIEPDASFASYGVDSIMAMALIAALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTVPTEPTASPASSAPPAASPPQPGDAHALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPVASPPQPGDAPALERMHAYLRDKLSQVLKLPPERIEPDASFASYGVDSIMAMALIAALEKELGSLPKTLFFEHETIEELGAYLLERCEPMPSGVEPATVGADDRAAYSGARPHAWPASPTEPDEPTEPTASPASSASPAASPPQPGDAHALERMHAYLRDKLSQVLKLPPERIETDASFASYGVDSIMAMALITALEKELGSLPKTLFFEHETIEELGEYLLERQGQERACHASNV
>NZ_CP004380.1|WP_004551645.1|1557949_1562650_-|DUF2156-domain-containing-protein
MQATFNPDEVALAGDARRTDGDADRAAASPHGFRFVEKARIADEPGLSARLAARKGDAHQDGVFLDLWPSIFLSDEHGDHIHVLRDRGLLFVTRFVGAPQREAALLSALLDRARGEGRALCYLDMSNRRKPDIERECGLLSTPLGVVQTIDDIRRFTLDGPRMRKLRYLVSKFGRDPSCRVVEYTEPDPAVDGEIRAVMAAWSREKGVVNKVDAILADMRVGNLLKRYRVYLTYLGDRLQNVVVLSHIGEGYITDQEYFVPDMPLGGTEYAYATIIERLAAEGHRKFSLGLTWGLFEPEAGFSDAEGWALVNRTEGQLAQIFRRGVQNHQYKNKYCPAEYPLYLYRSADSRPQIIKQCMGQFFRNGVPYDEIARQIEADDARALAAAGAAPPRATHGGDEAEARSAPGGAPDDARADAPDDASFDAPDGAPIEVSDHAPGSTPPPRAARDERGGERDDGKGGQAGQADRSGKHDPADAHGRAASGTPDAARAPAPADIPDAFFDATQADPNAIRLDLVSDSWAHLGYPFIRERARRLLAGLASPHADPAAPCGLFGVDHCVLTTSGRNAERVFFNLFPAKRKTILQNIPFFSTRHNAAKAGFASVEIPDPRIFDPDCREIFRGGIDFARLREQLEARPDGVAMVLIELCNNASGGYPVPLAQIADVSALCRARGVPFVMDVTRIVRNAELIRRHEPGCANVGLWDTVARIVAHADVVFGSLCKDFGVSAGGIVAANDGRLIGKARRYAEIEGALLDHVQTQVVCASLGERDALERGVAAQLDVARRVSDALDARRIPALLPVVGHCALVRAADMPGYAGRRYPRESLLRALLERHGVRAGIHLAGSGAERVIDRCIRIALPIGLDDARLASGLADALAGTAPGATDAPAALPDLLHARAPGAADTADTVDTVDKVDTADTADTADTADTADTADTAAQAGVRRGEAHASRAPMRASDDDAIAIVGMAGRYPGADDLSAFWRNLVDGVNAITEIPAERWDWRAHYHPDPEQAARLRKSYGKWGGFLGEFDCFDPLFFWMAPRRIAMIDPQERLFLEECWKALEDAGYPPSRLGDALRERTGVFGGLSKHGFSLYASQYAGTQPHTSPASMVGRVSHFFDLKGPSVAIDNHCASSLVAVHEACEYLRRGDGDLAIAGGVSLCLHPSSYVQLSLVRMLSRDAHCAAFDEGGAGYVPGEGVGVVVLKRLAQARAHGDPIHAVIRSGAVNHNGRMRYYGQPDQAGQQAAIRAALARARIDPRSISYIEAAASGVETTDAVEMAALTEVFGDRAGAAGAYTIGTVKPAIGHGEAASGMSQLMRVALSLKHATLTPTRLPRRPSPLIDFDRLPFRLAAEAAPWAPVSVDGRPVPRRAGVTAIGNGVNAHLVLEEWPGAPADDSAAAPREPQVFVLSAQDGERLAAYVERWIAFLASGATPDFGRMLRTLQIAREPMPARLALVASDRDDLLRALRAWRDGGASSRVHRGDARRRAGQAALAEQACDPRACAPDEAAAAWVQGRTVRWEALHRGGPWRRVGGLPAYPFARERYRIADAASGAPAGREEASARPD
>NZ_CP004380.1|WP_004549222.1|1556208_1557867_-|halogenase
MSNNQVRKYDVVIIGTGIGGTTLGAILARHGLRVAMIDSGTHPRFAVGESTIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPSCGVKRNFGFVYHREHTEQNPQEVNQALVVNEVHYFRQDIDAYMLHVAIRYGCDAYQNTVVDDIRIDAGGVTVTTRGGLTFEADFVADGAGYRSVLADKLGLRETPCRAKTHARGLFTHMIDVKPFDACREVPKALQQPVPWHQGTLHHLFDGGWMWVIPFNNTPESKNPLVSVGLMLDPRKHPKPDVRPEQEFADFIAKHPDMARQFADARAVREWVSSGRIQYSASECTGDRFCLLSHATGFIDPLFSRGLFNTMQTTNALAGLLIEAAKDRDFSKARFAPVEKLQQGLIDFNDRLVNCSYLSWGHYPLWNAWFRLWLLTGNYGQLHLQRVMMKYRQTGDARWLEPADALLPGAFTTLEPIMRLFEEAAVCVERYGAGELSGEAAERAIYALLEENAALLPPFFDFVSPAERITWPSTPEKIAALLLEWVERLPEDVRAEYFDYDVRALLQQPVVKDTITADVA
>NZ_CP004380.1|WP_004546727.1|1554683_1556126_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MTSEISGKRRWYALVVLCLGVLMIVLDTTIVNVALPSIAADLRFSENALVWVVNAYMLTFGGCLLLGGRLGDLYGHRRLFLAGVTVFTAASLACGLAQTQLVLIAARAAQGIGGAVVSSVALSLIMTLFVEPGDRAKAMGVYGFVYAGGGSLGVLLGGLLTSALSWHWVFLVNLPLGAVVYLLSSALLPKARAQATRASLDIAGAVTVTAALMLAVYAVVNGNAAGWLSARTLSWLGGAAALFAAFVAIEARVAHPLMPLALCMKRNVAIANLIGILWAAAMFAWFFLAALYLQRVLGYGPLQIGLAFLPANLIMGVFSLIVSALLVVRFGIRVPIAAGLLAAAAGLMLFARAPVGGDFVADVLPGMILLGTGAGIAFNPVLLAAMSGVDPADSGLASGIVNTSFMMGGALGLAVLASVATARTDALLAARTAVPAAMAGGYHAAFMLGAAFAIVAALIGMRLRAAPNPAAMQGLQGATQ
>NZ_CP004380.1|WP_004553366.1|1552142_1554014_+|chloride-channel-protein
MSIAAPHKRDFASNARLPRIALLALAIGVLSTFAAFALLSLIHLFTNLFFFQRFSFAEHSPALNTLGPWAAAVPVAGGIVVGLIARFGSEKIRGHGIPEAIEAILFGKSRMSPKVAVLKPLASGIVIGSGGPFGAEGPIIMTGGAIGSLIAQFVKVTAAERKTLLVAGATAGMTAVFGTPVAAVLLAVELLLFEWRPRSFLPVALACAVAGFARAAFFGVGPLFPVETAAPTAAALGSCALAGLLSGALACGLSVSLYKIEDRFGKLPVHWMWWPAIGGLAVGIGGLIEPRALGVGYDVIGDLLHGHIALQIALAILVVKAVIWVIALGSGTSGGVLAPLLMLGAGLGTLLGPVLPGGEPALWPLVCMAATLGATLGAPLTAIVFAFGLTHDANALLPLLTATLVAHGFATVAMKRSIMTEKIARRGYHIYREYGVDPLERHYVDEVMTRSAVTIDADLSVEVVRARYFGATQAHRAYPVVRDGVLIGMLDRATLDGSPAAHDGDGQADDARAAKMRAADVQMTDMRVADVRVADVLPRRAPLFSLADETCRLVATRLAVHQLERLPVVADPDTMRVVGIVSRSDLVKPALRHFDDEHKRERFRRAHPAAFVKRRFAPARKTG
>NZ_CP004380.1|WP_004524104.1|1551694_1552108_+|MarR-family-transcriptional-regulator
MTKPARELRKTDFEQLSEFRYQMRRFERFSERAAQSEGITPLQYLLLLHIKGYPERDWATVGELAERLQAQHHGVVALVTRCEALGLVRRRPSDADRRQVEVHLQAAGERVLARLAELHRAELKSLRGAFQVPQIDY
>NZ_CP004380.1|WP_004553367.1|1550360_1551554_+|HPP-family-protein
MSSSLAFAHRLARGLVRWLWRFVPIPVTLSRRERVRSCAGALVGIGCVGVTMRALPGRPGDVPLLVAPMGASAVLLFAVPASPLAQPWSLIGGNLVAATVGVACAQWIADPVLAASVAIAGAIGAMFALRCVHPPSGAVALTAVVGGPAVHALGFRFVAEPIALQSAALLGAALVYHALTGHRYPHGGAARPHADSNAHAAAAPLHARFVRADLEAALKNRSEWLDVAPEDLESLLRETELRAYARTFDELSCAEIMSRRPISIAPDTPLPAAMTLLERHRIKALPVVDADARVVGIVTRADLSKAAPYATPGFLRNLSARLPRSLVGPALVARAVMSTRVHTVRTTTPIAELVPLFADHGHHHIPVVDADHQLAGIVTQADLIAGLYRQSQVRLAA
>NZ_CP004380.1|WP_004198341.1|1550035_1550299_+|hypothetical-protein
MGNNGRREAASAAMRGRGRLIDRMRGPWDRLGAGIAGGKLCDSSRSDRANCTPMRAGALARAHFPHPETPTADRAIGGVGNLYHNDI
>NZ_CP004380.1|WP_004198340.1|1549043_1550015_-|LysR-family-transcriptional-regulator
MDMLDNMRLFVRVVEAGSFTAVAKEIDATTAQVSRAVSNLEAHVQTRLLHRTTRHLGLTESGQRYFERAKSILAEIDYANAEARNALLRPSGKLRIHAMTGLGQSHVVSSIVRYQEDNPDVSVELTLAQRMPNLVEEGYDVSIVSASHLPDSGYVAQTCGTSCSVLVASREYLARHGTPTTPDDLAKHVCLRLDTPASPGGEWRLERDDGDETVYALPPAPFQANVPDALSVAVRAGRGIGSIALYTALDDIREGRLVRVLPNYRLDTLSVYAVYATRRYLDAKIRTFLDHLRTTLAPALENDLKELNRLNGGVGKKALREVA
>NZ_CP004380.1|WP_004524106.1|1547446_1548532_+|ionic-transporter-y4hA
MPISSSALPRWTLVAPLAAWLVLALSRVVPAEGFAIAFVAAALAGAVFSAVHHAEVVAHRVGEPFGTLVLAIAVTVIEVALIVSVMLSAGPEKAGLARDTVFAAVMIVCNGIVGLCLLVGGWRHGEQDFQGRGATKALAVLASLSVLSLVMPNYLSAAPGPRLSTSQLAFAGVSSLVLYGVFVFVQTVRHRDYFLIDGSADESVHAVPPSGRTALTSIAFLFVSLVAVVLLAKLLSPAVERTVLRLGAPEAAVGIVIAALVLLPEGLAAVGAARANRLQTSMNLALGSALASIGLTIPTVAAVFIWTGAPLTLGIGAMETVLLSLTLLVSTLTLSLGRTTVLHGVVHLSLFAAYLFLSITH
>NZ_CP004380.1|WP_004553360.1|1611036_1612269_+|sodium/hydrogen-exchanger
MNSIFVFLSQALLIVAVPPLLMNYLRVGAVVPLVVVQIVFGVVIGPSGLGRLSPETYTALFPPDSLTFLSHVSAIALFFFAIVTGLHLDATGLRGHGRKLGLISTASMLAPMSLGVLAGIAISARYPQALDPHASVAEFVAGIGICCGVTALPVLAAILRETNLTSRRLGQFSLALAAVNDGMLWILLAAFLSVTGANAANGGRLFITSALIVLYFVSILFVVRPLLLVLANRLRTSVDTQILIACAVAVASAAATDRLGLHYLLGAFIAGAIIPGAWRDALLERMQPVTVNVLTPFFFISTGLRVLIDVDAPGFLQITLIITLCTAIGKIAGTTLAARMTGESWGFCLGLGFLAQAKGLMELVVATILLDSHVISRTVFSALILMALISTAFAMPMLRLKPVRGAALSA
>NZ_CP004380.1|WP_004553359.1|1612653_1613838_+|ACP-S-malonyltransferase
MLNTFMFPGQGSQAKGMGGALFDRFADLTAQADAVLGYSIRALCVDDPRDELGRTQFTQPALYVVNALTYYAKCEDSGETPDFLAGHSLGEFNALLAAGCFDFEAGLKLVARRAELMSQARDGAMAAIVNASREQIERTLDEHGLVDTAIANDNTPSQLVISGPAHEIARAEALFQHDRVRYLRLNTSGAFHSKFMRPAQQAFAAHLQSFRLADPAIPVISNVSARPYENGRVSEGLAQQIASPVRWCESIRYLLALAAERGEAIEFTELGHGDVLTRLVHTIRRQTPAPAAAPAAAATSARARPTPPGEPERLAQQTAAAPRASDSASASLGAAERVAAWNRDYPVGTRVRSSLIHDDVLETRTPATVLFGHRAAVYMKGYNGYFDLAEVTPA
>NZ_CP004380.1|WP_004198258.1|1614887_1615121_+|hypothetical-protein
MRREAAWRARPLIPNEPRGPASGRHFSLQEPVLTDDTAAAPPSAFYICAEFFSIIEHSVFYDFLPPHFRLATEKSMM
>NZ_CP004380.1|WP_004528251.1|1615232_1616492_+|hydroxymethylglutaryl-CoA-synthase-family-protein
MTAVGIEALNVYAGVASLDVSRLAEHRKLDMARFQNLLMREKSVALPYEDPITYGVNAAKPIVDALTPDERDRIEMLITCTESAFDFGKSMSTYFHHHLGLKRNCRLFEVKNACYSGVAGLQTAINFILAQVSPGAKALVIATDLSRFIVEEGGEALSADWSFAEPSSGAGAVAMLVSDTPHVFRIDVGANGYYGYEVMDTCRPTTDSEAGNSDLSLLSYLDCCENAFLEYQKRVCDVDYASTFGFLAFHTPFGGMVKGAHRNLMRKASRCSTQEIEQDFQRRAGPGLVYCQRLGNIMGATAMLSVASTIDNGEYRAPQRVGVFSYGSGCCSEFFSGIVDEEGQRRLRGMRIGEQLDRRYALSIDEYEHVLKESRVVRFGTRNAKIDDGFIPAARRAHSRETLFLSRINEYHREYEWIC
>NZ_CP004380.1|WP_004198262.1|1616485_1617256_+|enoyl-CoA-hydratase/isomerase
MLSRPADYRTIRVRYDGDICFLQLHRPDAQNAINNRMIAECMDVLDRCEHAAKIVVLQGLPDVFCFGADFSDIAEKPDALIDSDAIYGLWHRLATGPYITIAHVQGKVNAGGIGFVAASDIAICDENVPFSLSELLFGLIPACVLPFLARRIGTPKAHYMTLMTQPVTAQQAFSWGLVDAIGANTDTLVRKHLLRLRCLNKASVARYKSYAATLDDTLAAARPGAVRVSIEMFADPENRRKIARYVDTGKFPWEAD
>NZ_CP004380.1|WP_004532917.1|1617256_1618039_+|enoyl-CoA-hydratase
MSAHERVVEIREVADCVVQVVMQDRENKNTFSDALIRGLGEAFDAIRQNGRCKAAILTGYGNYFASGGTQESLMYLSEGKGTFAEIAASASRNGANLYSLALNCPVPVIAAMQGHGIGGGFVMGLFADFVVLGKECLYTTNFMKYGFTPGMGATLVLPHKLGLPLAQNMLMTARSFYGDELQKLGVPFPVVPRAEVAACALEIAKNLAEKPRLSLVTLKDHLVAELRSRLPAVIEQELAMHEKTFGQPEVKERIRSLFGQ
>NZ_CP004380.1|WP_004198264.1|1618092_1618332_+|acyl-carrier-protein
MDLQQVFDIIVRHTKEVIPGLDRHAFRTTDALKDLGANSLDRSEIVIMTLESLSLRIPLVEFAGARNIGELAEVLYAKL
>NZ_CP004380.1|WP_004539120.1|1618318_1619563_+|polyketide-beta-ketoacyl:ACP-synthase
MRSSERDEILVTGVGVVSAIGQGRQPFIDALLDGRHAFGVMRRPGRQLPDDAGAGPAPAFFGAEIDSIALPPMLDAHRRTASYSAQAAVACVREAWDDAALGDVDPLRIGLVVGGSNVQQREQALVHDTYRGRYAFLRPSYGLSFMDSDLCGLCTELFGIRGVAFTVGGASASGQLAVLQACRLVESGSVDACIAVGALMDLSYWECQALRSLGAMGSDRFADEPDAACRPFDQDRDGFIYGECSGAIVVERAARMRRAHVSPYAKWLGGCIRMDGTREPAPSLDGEMAVIEGALRDAGIGADSIDYVNPHGSGSTLGDATELDALGRSGLAHARINTTKSLVGHGLSAAGIVELIATLLQMRARRLHPSRNLDQPIDERFDWVRSTCGSDIRRALKLSIGFGGINTALCLERC
>NZ_CP004380.1|WP_004531777.1|1619604_1621284_+|hypothetical-protein
MGDYLAQDARIERITVRDPEARTWFDRGLLWAYGFNFEAAVDCFQEAARIDPDCVLAYWGIAYASGCNYNKQWKVFHPRMIARCMKLARDAIRRAQACRAGASALEMALVRAIECRFQAEGAHDEALLRRWNDDYARAMRDVYLSCPDNLDVAALFADALINRTPWKLWDMSSGKTADGADTDEAIAVLERALAQVDANGLAPHPGLLHVYIHTIEMSPTPEKALRAADALRDLAPDVGHLLHMASHIDILCGHYHDAIVANDRAIAANQRVLDRHPQWLEFRLYCVHDIHFKIYAAMMLGRFSAAWQGVLELEALITEALLRVEQPPMAYLLEGFLSVRVHVLIRFGKWREILEQPFPANAALYCNTTAMLHYARGIAYANLKLAGPAAQARRAFSIAQAALHEHRYVTNNTCADLLKIAACVLDGEIAYHEDRFDEAFAHLRRAVELDDGLEYMEPWGWMMPTRHPLGALLLAQGHVEEAERVYRADLGLDSTIYRSLQHPGNVWSLQGYVSCLRRLGKHETADALQPALDVARARADVEIGVSCFCAAPSKRGCCH
>NZ_CP004380.1|WP_004524091.1|1621449_1622454_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MNGTQRFPMDIPFGWFCIGYSDEVAVGDVKPLRYFGKDLVMFRGESGEIGVLDAYCPHLGAHMGHGGTVEGDSLRCPFHHWAYRKDGFCTSIPYAKEMPLIAKREPIAVPYPVVERNGAIWVWHHPQQIAPTYEVLEHEEFVAPGWSKPVRRFWSFASNPQEIAENGVDTAHFKCIHHMDAMPEGEVSYEGHIRRSRTTGETSMIFPDGVTRTVETGTNVINSGAGQKISRFTGFVTISLMEMATPVEADQVELRFCFAFPECPEGSPEWQGAMNTIDYFSGQLGIEGGDIPIWSHKIHREKPILCDGDGAIMRFRRYFEQFYAPRVVPVTASA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP004380.1	1586476-1586499	0	1.0
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP004380.1	1586485-1586508	0	1.0
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP004380.1	1586494-1586517	0	1.0
NZ_CP004380_4	4.2\|1588184\|24\|NZ_CP004380\|CRISPRCasFinder	1588184-1588207	24	NZ_CP004380.1	1588229-1588252	2	0.917
NZ_CP004380_4	4.2\|1588184\|24\|NZ_CP004380\|CRISPRCasFinder	1588184-1588207	24	NZ_CP004380.1	1594586-1594609	2	0.917

1. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to position: 1586476-1586499, mismatch: 0, identity: 1.0

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgcttgcggtgcttgcggtgct	Protospacer
************************

2. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to position: 1586485-1586508, mismatch: 0, identity: 1.0

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgcttgcggtgcttgcggtgct	Protospacer
************************

3. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to position: 1586494-1586517, mismatch: 0, identity: 1.0

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgcttgcggtgcttgcggtgct	Protospacer
************************

4. spacer 4.2|1588184|24|NZ_CP004380|CRISPRCasFinder matches to position: 1588229-1588252, mismatch: 2, identity: 0.917

gtgtcgtgcgtgtcgtgcgtgtcg	CRISPR spacer
gtgtcgtgcatgtcgtgcatgtcg	Protospacer
*********.********.*****

5. spacer 4.2|1588184|24|NZ_CP004380|CRISPRCasFinder matches to position: 1594586-1594609, mismatch: 2, identity: 0.917

gtgtcgtgcgtgtcgtgcgtgtcg	CRISPR spacer
gtgtcgttcgtgtcgttcgtgtcg	Protospacer
******* ******** *******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1838872-1838895	2	0.917
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1005682-1005705	2	0.917
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	MG592671	Vibrio phage 2.275.O._10N.286.54.E11, partial genome	90209-90232	2	0.917
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP034347	Roseovarius sp. MME-070 plasmid pMME07001, complete sequence	10373-10396	2	0.917
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	728225-728248	2	0.917
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	728234-728257	2	0.917
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NC_003276	Nostoc sp. PCC 7120 = FACHB-418 plasmid pCC7120alpha, complete sequence	322483-322506	2	0.917
NZ_CP004380_3	3.2\|1587251\|24\|NZ_CP004380\|CRISPRCasFinder	1587251-1587274	24	NC_019691	Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence	56968-56991	2	0.917
NZ_CP004380_4	4.2\|1588184\|24\|NZ_CP004380\|CRISPRCasFinder	1588184-1588207	24	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	230907-230930	2	0.917
NZ_CP004380_4	4.2\|1588184\|24\|NZ_CP004380\|CRISPRCasFinder	1588184-1588207	24	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	682861-682884	2	0.917
NZ_CP004380_4	4.2\|1588184\|24\|NZ_CP004380\|CRISPRCasFinder	1588184-1588207	24	NC_012720	Burkholderia glumae BGR1 plasmid bglu_3p, complete sequence	66872-66895	2	0.917
NZ_CP004380_4	4.2\|1588184\|24\|NZ_CP004380\|CRISPRCasFinder	1588184-1588207	24	JX006077	Saccharomonospora phage PIS 136, complete genome	26223-26246	2	0.917
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP016082	Streptomyces sp. SAT1 plasmid unnamed2, complete sequence	223399-223422	3	0.875
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	974785-974808	3	0.875
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP049906	Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence	286680-286703	3	0.875
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP017565	Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence	266077-266100	3	0.875
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP017565	Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence	266086-266109	3	0.875
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP017565	Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence	266095-266118	3	0.875
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP017565	Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence	266104-266127	3	0.875
NZ_CP004380_4	4.2\|1588184\|24\|NZ_CP004380\|CRISPRCasFinder	1588184-1588207	24	MG592456	Vibrio phage 1.081.O._10N.286.52.C2, partial genome	47045-47068	3	0.875
NZ_CP004380_2	2.1\|1586431\|24\|NZ_CP004380\|CRISPRCasFinder	1586431-1586454	24	NZ_CP009431	Sphingopyxis macrogoltabida strain 203 plasmid unnamed, complete sequence	23053-23076	4	0.833
NZ_CP004380_4	4.1\|1588112\|33\|NZ_CP004380\|CRISPRCasFinder	1588112-1588144	33	NZ_CP034156	Rhodococcus sp. NJ-530 plasmid unnamed4, complete sequence	432484-432516	9	0.727
NZ_CP004380_4	4.1\|1588112\|33\|NZ_CP004380\|CRISPRCasFinder	1588112-1588144	33	NZ_CP014942	Rhodococcus sp. BH4 plasmid, complete sequence	339146-339178	10	0.697
NZ_CP004380_4	4.1\|1588112\|33\|NZ_CP004380\|CRISPRCasFinder	1588112-1588144	33	NZ_CP017303	Rhodococcus sp. YL-1 plasmid pYLL1 sequence	229899-229931	10	0.697

1. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 2, identity: 0.917

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgcttgcgatgcttgcggtgcc	Protospacer
**********.************.

2. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 2, identity: 0.917

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgctggcggtgctggcggtgct	Protospacer
****** ******** ********

3. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to MG592671 (Vibrio phage 2.275.O._10N.286.54.E11, partial genome) position: , mismatch: 2, identity: 0.917

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgcttggggtgcttggggtgct	Protospacer
******** ******** ******

4. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP034347 (Roseovarius sp. MME-070 plasmid pMME07001, complete sequence) position: , mismatch: 2, identity: 0.917

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgatcgcggtgcttgcggtgct	Protospacer
**** *.*****************

5. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 2, identity: 0.917

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgcttccggtgcttccggtgct	Protospacer
******* ******** *******

6. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 2, identity: 0.917

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgcttccggtgcttccggtgct	Protospacer
******* ******** *******

7. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NC_003276 (Nostoc sp. PCC 7120 = FACHB-418 plasmid pCC7120alpha, complete sequence) position: , mismatch: 2, identity: 0.917

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgctggcggtgctggcggtgct	Protospacer
****** ******** ********

8. spacer 3.2|1587251|24|NZ_CP004380|CRISPRCasFinder matches to NC_019691 (Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence) position: , mismatch: 2, identity: 0.917

atagcctgcatagcctgcatagcc	CRISPR spacer
atagcgtgcatagccttcatagcc	Protospacer
***** ********** *******

9. spacer 4.2|1588184|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gtgtcgtgcgtgtcgtgcgtgtcg	CRISPR spacer
gtgtcgtgcgcgtcgtgcgcgtcg	Protospacer
**********.********.****

10. spacer 4.2|1588184|24|NZ_CP004380|CRISPRCasFinder matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 2, identity: 0.917

gtgtcgtgcgtgtcgtgcgtgtcg	CRISPR spacer
gtgtcgtgcgtgtcgtacgcgtcg	Protospacer
****************.**.****

11. spacer 4.2|1588184|24|NZ_CP004380|CRISPRCasFinder matches to NC_012720 (Burkholderia glumae BGR1 plasmid bglu_3p, complete sequence) position: , mismatch: 2, identity: 0.917

gtgtcgtgcgtgtcgtgcgtgtcg	CRISPR spacer
gtgtcgtccgtgtcgtccgtgtcg	Protospacer
******* ******** *******

12. spacer 4.2|1588184|24|NZ_CP004380|CRISPRCasFinder matches to JX006077 (Saccharomonospora phage PIS 136, complete genome) position: , mismatch: 2, identity: 0.917

gtgtcgtgcgtgtcgtgcgtgtcg	CRISPR spacer
gtgtcgtgcgtgtcgtgcgggacg	Protospacer
******************* * **

13. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP016082 (Streptomyces sp. SAT1 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.875

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
agtgcttgcagtgcttgcagtgct	Protospacer
.********.********.*****

14. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.875

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgctggcggtgctggcggtgcc	Protospacer
****** ******** *******.

15. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP049906 (Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.875

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgctagcggtgctagcggtgcc	Protospacer
****** ******** *******.

16. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP017565 (Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence) position: , mismatch: 3, identity: 0.875

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
tgtgcttgctgtgcttgctgtgct	Protospacer
 ******** ******** *****

17. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP017565 (Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence) position: , mismatch: 3, identity: 0.875

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
tgtgcttgctgtgcttgctgtgct	Protospacer
 ******** ******** *****

18. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP017565 (Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence) position: , mismatch: 3, identity: 0.875

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
tgtgcttgctgtgcttgctgtgct	Protospacer
 ******** ******** *****

19. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP017565 (Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence) position: , mismatch: 3, identity: 0.875

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
tgtgcttgctgtgcttgctgtgct	Protospacer
 ******** ******** *****

20. spacer 4.2|1588184|24|NZ_CP004380|CRISPRCasFinder matches to MG592456 (Vibrio phage 1.081.O._10N.286.52.C2, partial genome) position: , mismatch: 3, identity: 0.875

gtgtcgtgcgtgtcgtgcgtgtcg	CRISPR spacer
gtgtcgtacgtgtcgtacgtgtca	Protospacer
*******.********.******.

21. spacer 2.1|1586431|24|NZ_CP004380|CRISPRCasFinder matches to NZ_CP009431 (Sphingopyxis macrogoltabida strain 203 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.833

ggtgcttgcggtgcttgcggtgct	CRISPR spacer
ggtgcttgcggtgcttgcgacgaa	Protospacer
*******************..*

22. spacer 4.1|1588112|33|NZ_CP004380|CRISPRCasFinder matches to NZ_CP034156 (Rhodococcus sp. NJ-530 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.727

atgtcctgcgtgtcgtgcatgtcatgcatgtca	CRISPR spacer
actctgtgcgtgtcgtgcatttcatgcatgctt	Protospacer
*. .. ************** *********..

23. spacer 4.1|1588112|33|NZ_CP004380|CRISPRCasFinder matches to NZ_CP014942 (Rhodococcus sp. BH4 plasmid, complete sequence) position: , mismatch: 10, identity: 0.697

atgtcctgcgtgtcgtgcatgtcatgcatgtca	CRISPR spacer
actctgtgcgtgtcgtgcatttcgtgcatgctt	Protospacer
*. .. ************** **.******..

24. spacer 4.1|1588112|33|NZ_CP004380|CRISPRCasFinder matches to NZ_CP017303 (Rhodococcus sp. YL-1 plasmid pYLL1 sequence) position: , mismatch: 10, identity: 0.697

atgtcctgcgtgtcgtgcatgtcatgcatgtca	CRISPR spacer
actctgtgcgtgtcgtgcatttcgtgcatgctt	Protospacer
*. .. ************** **.******..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

119423 : 149074

Acanthocystis_turfacea_Chlorella_virus(20.0%)

transposase,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190585.1\|119423_120827_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004190689.1\|120842_122159_+	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_004524806.1\|122161_125791_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_122985123.1\|125772_126729_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004529325.1\|126713_126941_-	hypothetical protein	NA	NA	NA	NA
WP_004552196.1\|126939_129549_+	serine/threonine protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	5.0e-09	26.6
WP_004190988.1\|129601_130681_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004524810.1\|130743_131322_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190849.1\|131314_132823_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004190698.1\|132882_133374_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_009935240.1\|133392_133941_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004553897.1\|133945_135817_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_100227576.1\|135813_137259_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004533146.1\|137271_139938_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	5.2e-78	30.6
WP_004203275.1\|139934_142139_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004539259.1\|142154_142865_+	hypothetical protein	NA	NA	NA	NA
WP_157726745.1\|144574_144808_+\|transposase	transposase	S5WIU1	Leptospira_phage	3.9e-14	58.6
WP_076823047.1\|145815_146106_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004546292.1\|146116_147268_-	hypothetical protein	NA	NA	NA	NA
WP_085965013.1\|147894_149074_+\|transposase	IS3-like element ISBps1 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.2e-60	42.9

DBSCAN-SWA_2

902916 : 931550

Acinetobacter_phage(33.33%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080015562.1\|902916_903501_-\|transposase	transposase	NA	NA	NA	NA
WP_004557777.1\|903818_904106_+\|transposase	transposase	NA	NA	NA	NA
WP_004553525.1\|904190_904634_+	hypothetical protein	NA	NA	NA	NA
WP_004533180.1\|904665_906195_+	type III secretion system effector BopC	NA	NA	NA	NA
WP_004528803.1\|907255_907888_-	GTP cyclohydrolase I	A0A0P0HSD2	Acinetobacter_phage	9.9e-20	30.6
WP_004551882.1\|907892_908186_-	hypothetical protein	NA	NA	NA	NA
WP_004528802.1\|908144_908390_+	hypothetical protein	NA	NA	NA	NA
WP_004553524.1\|908349_909573_-	peptidase	NA	NA	NA	NA
WP_045586959.1\|910281_914349_-	type VI secretion system protein ImpL	NA	NA	NA	NA
WP_004184888.1\|914360_915026_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004536933.1\|915022_916420_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004533362.1\|916452_917250_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004553521.1\|917259_917652_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004551877.1\|917680_918433_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004528797.1\|918429_919494_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004553520.1\|919511_922154_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_004553519.1\|922179_925203_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.2e-22	24.8
WP_014696879.1\|925229_928313_-	AAA domain-containing protein	A0A223W0B1	Agrobacterium_phage	7.1e-79	29.8
WP_004525341.1\|928299_929322_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004553517.1\|929309_931052_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004530572.1\|931088_931550_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_3

2165989 : 2233775

Aeromonas_phage(25.0%)

holin,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004535035.1\|2165989_2166940_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004523149.1\|2167207_2168152_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004530060.1\|2168623_2170327_+	thermolysin metallopeptidase	NA	NA	NA	NA
WP_004530059.1\|2170444_2171671_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_004200640.1\|2171725_2172868_-	porin	NA	NA	NA	NA
WP_004198249.1\|2172976_2173099_-	hypothetical protein	NA	NA	NA	NA
WP_004530058.1\|2173095_2174133_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004186939.1\|2174129_2175683_-\|holin	choline-sulfatase	NA	NA	NA	NA
WP_004551409.1\|2175845_2176718_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004186920.1\|2176861_2177737_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_004530057.1\|2177823_2179479_-	APC family permease	NA	NA	NA	NA
WP_004186918.1\|2179659_2180523_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004530056.1\|2180632_2181778_-	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004535147.1\|2181798_2183040_-	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004530055.1\|2183091_2183877_-	drug:proton antiporter	NA	NA	NA	NA
WP_004523138.1\|2183873_2185046_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004186901.1\|2185050_2186976_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004186960.1\|2186978_2189042_-	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_004186987.1\|2189102_2189636_-	4-vinyl reductase	NA	NA	NA	NA
WP_004535113.1\|2189786_2190758_-	membrane dipeptidase	NA	NA	NA	NA
WP_004523136.1\|2190830_2192105_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	5.3e-105	54.1
WP_009933096.1\|2192116_2192368_-	hypothetical protein	NA	NA	NA	NA
WP_004198247.1\|2192537_2193563_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004523135.1\|2193740_2194940_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	8.4e-12	27.2
WP_009971500.1\|2195387_2196404_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_023358579.1\|2196592_2198158_+	glycoside hydrolase 68 family protein	NA	NA	NA	NA
WP_009971496.1\|2198290_2199958_+	glycoside hydrolase family 32 protein	F8WPR5	Bacillus_phage	3.5e-56	31.4
WP_004547675.1\|2200481_2201735_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004528656.1\|2202461_2204045_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_038724161.1\|2204041_2204224_-	hypothetical protein	NA	NA	NA	NA
WP_004524284.1\|2204349_2205345_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_004528658.1\|2205633_2207220_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_024428512.1\|2207216_2208536_-	glycosyltransferase	NA	NA	NA	NA
WP_004547901.1\|2208425_2208728_+	hypothetical protein	NA	NA	NA	NA
WP_004528661.1\|2208769_2209669_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_004536812.1\|2210219_2210495_-	hypothetical protein	NA	NA	NA	NA
WP_004190471.1\|2210815_2211241_-	hypothetical protein	NA	NA	NA	NA
WP_004190863.1\|2211263_2211623_-	hypothetical protein	NA	NA	NA	NA
WP_004190265.1\|2211681_2215185_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004525553.1\|2215181_2216840_-	OmpA family protein	NA	NA	NA	NA
WP_004525552.1\|2216922_2218284_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004202226.1\|2218280_2218874_-	hypothetical protein	NA	NA	NA	NA
WP_004190606.1\|2218879_2219269_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004530790.1\|2219311_2220028_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004525550.1\|2220030_2221101_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004547074.1\|2221100_2223317_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_004190563.1\|2223320_2225609_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_014696850.1\|2225774_2228063_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004525547.1\|2228053_2230924_-	type VI secretion system ATPase TssH	A0A2I7REQ1	Vibrio_phage	2.4e-60	27.2
WP_004190851.1\|2230926_2231916_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004196180.1\|2231912_2233775_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_4

2390362 : 2418348

Leptospira_phage(33.33%)

integrase,transposase

attL 2367114:2367129|attR 2424610:2424625

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2367114:2367129	attL	NA	NA	NA	NA
WP_122802116.1\|2390362_2391052_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_004553178.1\|2391495_2392428_-	glycerophosphoryl diester phosphodiesterase	NA	NA	NA	NA
WP_004530738.1\|2392584_2393847_-	c-type cytochrome	NA	NA	NA	NA
WP_004538070.1\|2394005_2395466_-	ser/threonine protein phosphatase	NA	NA	NA	NA
WP_004525420.1\|2398734_2399019_-	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	1.4e-10	50.0
WP_009923450.1\|2399002_2399272_-	BrnT family toxin	NA	NA	NA	NA
WP_038802333.1\|2400020_2401141_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004553173.1\|2401653_2403357_-\|integrase	site-specific integrase	A0A059XK29	uncultured_phage	2.0e-19	33.5
WP_038742112.1\|2403659_2404847_+\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	2.1e-124	57.3
WP_080014899.1\|2405189_2405507_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_004553171.1\|2405507_2406617_+	DUF927 domain-containing protein	NA	NA	NA	NA
WP_038802950.1\|2406661_2407782_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004553168.1\|2407862_2408669_+	hypothetical protein	NA	NA	NA	NA
WP_004553167.1\|2408764_2409340_-	hypothetical protein	NA	NA	NA	NA
WP_004553166.1\|2409574_2409826_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004553165.1\|2409876_2410383_-	hypothetical protein	NA	NA	NA	NA
WP_004553164.1\|2410526_2410820_-	hypothetical protein	NA	NA	NA	NA
WP_129195150.1\|2411548_2411758_-	hypothetical protein	NA	NA	NA	NA
WP_080014896.1\|2412297_2413446_+	hypothetical protein	NA	NA	NA	NA
WP_076888374.1\|2413395_2414334_-	site-specific DNA-methyltransferase	A0A1D8KJ61	Synechococcus_phage	2.4e-14	48.9
WP_004553163.1\|2414330_2416514_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_076888373.1\|2416458_2416665_-	CopG family transcriptional regulator	NA	NA	NA	NA
WP_085952178.1\|2417236_2418348_-\|transposase	IS3-like element ISBp1 family transposase	NA	NA	NA	NA
2424610:2424625	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP004379

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP004379_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004379_1

427795-427874

Orphan

Consensus_repeat	Method
ACGGAATGGGCCCCGGCATGATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP004379_1

>merge|NZ_CP004379|1|427795-427874|CRISPRCasFinder
ACGGAATGGGCCCCGGCATGATGGGCGGCGGCTACGGGCGCGGAATGATGGGCGGCTACGGAATGGGGCCCGGCATGATG

>NZ_CP004379|1|1|427795-427874|CRISPRCasFinder
ACGGAATGGGCCCCGGCATGATG	GGCGGCGGCTACGGGCGCGGAATGATGGGCGGCT
ACGGAATGGGGCCCGGCATGATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004379.1\|WP_024428817.1\|422725_423190_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_004553742.1\|429609_431058_+\|RNA-polymerase-sigma-factor-RpoD/SigA	unknown	unknown	gnl\|CDD\|274108
NZ_CP004379.1\|WP_004536377.1\|426590_427559_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP004379.1\|WP_004553740.1\|433786_434881_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	unknown	unknown	gnl\|CDD\|185333
NZ_CP004379.1\|WP_004536006.1\|424212_425325_-\|histone-deacetylase	unknown	unknown	gnl\|CDD\|212521
NZ_CP004379.1\|WP_154218334.1\|418386_418755_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_038742490.1\|421235_422327_-\|phage-portal-protein	unknown	unknown	gnl\|CDD\|222860
NZ_CP004379.1\|WP_004553741.1\|432848_433790_-\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
NZ_CP004379.1\|WP_004197761.1\|435282_435699_+\|lactoylglutathione-lyase	unknown	unknown	gnl\|CDD\|319916
NZ_CP004379.1\|WP_004553737.1\|438924_440082_-\|DUF4382-domain-containing-protein	unknown	unknown	gnl\|CDD\|379555
NZ_CP004379.1\|WP_004553743.1\|425353_426448_-\|polyamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270377
NZ_CP004379.1\|WP_004189258.1\|423326_424202_-\|N-carbamoylputrescine-amidase	unknown	unknown	gnl\|CDD\|274553
NZ_CP004379.1\|WP_004530511.1\|435866_436421_-\|YaeQ-family-protein	unknown	unknown	gnl\|CDD\|377782
NZ_CP004379.1\|WP_004523107.1\|420877_421162_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_004525837.1\|428798_429347_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_004200731.1\|420398_420881_+\|DUF2778-domain-containing-protein	unknown	unknown	gnl\|CDD\|378506
NZ_CP004379.1\|WP_004545670.1\|431076_432690_-\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|235001
NZ_CP004379.1\|WP_004524603.1\|437470_438031_-\|spermidine-N1-acetyltransferase	unknown	unknown	gnl\|CDD\|237916
NZ_CP004379.1\|WP_004525830.1\|436636_436984_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_004553744.1\|418856_419861_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369676

Protein	Function_ID	Function_description	E-value
NZ_CP004379.1\|WP_004553740.1\|433786_434881_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	gnl\|CDD\|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	1.3927e-121
NZ_CP004379.1\|WP_004536377.1\|426590_427559_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.03052e-69
NZ_CP004379.1\|WP_004536006.1\|424212_425325_-\|histone-deacetylase	gnl\|CDD\|212521	cd09996, HDAC_classII_1, Histone deacetylases and histone-like deacetylases, classII. This subfamily includes bacterial as well as eukaryotic Class II histone deacetylase (HDAC) and related proteins. Deacetylases of class II are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. Included in this family is a bacterial HDAC-like amidohydrolase (Bordetella/Alcaligenes species FB18817, denoted as FB188 HDAH) shown to be most similar in sequence and function to class II HDAC6 domain 3 or b (HDAC6b). FB188 HDAH is able to remove the acetyl moiety from acetylated histones, and can be inhibited by common HDAC inhibitors such as SAHA (suberoylanilide hydroxamic acid) as well as class II-specific but not class I specific inhibitors.	5.49698e-171
NZ_CP004379.1\|WP_004553742.1\|429609_431058_+\|RNA-polymerase-sigma-factor-RpoD/SigA	gnl\|CDD\|274108	TIGR02393, RNA_polymerase_sigma_factor_RpoD, RNA polymerase sigma factor RpoD, C-terminal domain. This model represents the well-conserved C-terminal region of the major, essential sigma factor of most bacteria. Members of this clade show considerable variability in domain architecture and molecular weight, as well as in nomenclature: RpoD in E. coli and other Proteobacteria, SigA in Bacillus subtilis and many other Gram-positive bacteria, HrdB in Streptomyces, MysA in Mycobacterium smegmatis, etc. [Transcription, Transcription factors].	3.067e-88
NZ_CP004379.1\|WP_004553741.1\|432848_433790_-\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	9.45664e-54
NZ_CP004379.1\|WP_004197761.1\|435282_435699_+\|lactoylglutathione-lyase	gnl\|CDD\|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.46868e-30
NZ_CP004379.1\|WP_004553737.1\|438924_440082_-\|DUF4382-domain-containing-protein	gnl\|CDD\|379555	pfam14321, DUF4382, Domain of unknown function (DUF4382). This family is found in bacteria and archaea, and is typically between 142 and 161 amino acids in length.	8.1908e-48
NZ_CP004379.1\|WP_004553743.1\|425353_426448_-\|polyamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.40923e-149
NZ_CP004379.1\|WP_004189258.1\|423326_424202_-\|N-carbamoylputrescine-amidase	gnl\|CDD\|274553	TIGR03381, putative_carbon-nitrogen_hydrolase, N-carbamoylputrescine amidase. Members of this family are N-carbamoylputrescine amidase (3.5.1.53). Bacterial genes are designated AguB. The AguAB pathway replaces SpeB for conversion of agmatine to putrescine in two steps rather than one. [Central intermediary metabolism, Polyamine biosynthesis].	0
NZ_CP004379.1\|WP_004530511.1\|435866_436421_-\|YaeQ-family-protein	gnl\|CDD\|377782	pfam07152, YaeQ, YaeQ protein. This family consists of several hypothetical bacterial proteins of around 180 residues in length which are often known as YaeQ. YaeQ is homologous to RfaH, a specialized transcription elongation protein. YaeQ is known to compensate for loss of RfaH function.	1.52049e-103
NZ_CP004379.1\|WP_004553744.1\|418856_419861_+\|hypothetical-protein	gnl\|CDD\|369676	pfam08065, K167R, K167R (NUC007) repeat. This family represents the K167/Chmadrin repeat. The function of this repeat is unknown.	0.0060801
NZ_CP004379.1\|WP_004200731.1\|420398_420881_+\|DUF2778-domain-containing-protein	gnl\|CDD\|378506	pfam10908, DUF2778, Protein of unknown function (DUF2778). This is a bacterial family of uncharacterized proteins.	2.57059e-50
NZ_CP004379.1\|WP_004545670.1\|431076_432690_-\|glutamate--cysteine-ligase	gnl\|CDD\|235001	PRK02107, PRK02107, glutamate--cysteine ligase; Provisional.	0
NZ_CP004379.1\|WP_004524603.1\|437470_438031_-\|spermidine-N1-acetyltransferase	gnl\|CDD\|237916	PRK15130, PRK15130, spermidine N1-acetyltransferase; Provisional.	7.47948e-86
NZ_CP004379.1\|WP_038742490.1\|421235_422327_-\|phage-portal-protein	gnl\|CDD\|222860	PHA02536, Q, portal vertex protein; Provisional.	0

>NZ_CP004379.1|WP_004536377.1|426590_427559_+|LysR-family-transcriptional-regulator
MRRIDLLSALETFVCAVEEGSLSQAARRLAKTPSAVTKAIAGLEATLGVQLLERTTRRLALTESGRLYLATATDVLRRLADGARQLSERDDEPRGLLRVTAAHSFGHAILAPLCAPFAQAFPRVRIELSLSDHYVDIVGEGFDLALRMGNYDLPSQIVKPIGSNRGLPCASPGYLARRGRPTAPADLAQHDCVIYRHPTLANTWTFERGGVRARLEPKGPLVTDDYGLALAAALDGAGVLPCPQWSVVDALEAGRLVPLLIDWRFESASFGEDRICAAYPSSRRGSTKIRRLVERVQARLADSEARVAHVLGDALCADLARR
>NZ_CP004379.1|WP_004553743.1|425353_426448_-|polyamine-ABC-transporter-substrate-binding-protein
MKRIAWLAAVLASLACAAARAAGGNVLNIYNWAEYFAPDTIAGFEKETGIKVRLDVYDSNEALQTKLTTGNSGYDLVFPSNDFLARQIQAGLYRKLDKSRLPNLTNLDPAIVARAAEVDPGNQYSVPYMQGTFGLGLNVAKVKQALGGPLPANTLELIFNPAYAAKLERCGIAFNDAGSEVFPLALRYIGRDPNTTDPRDYEAALDMMKTIRPTIRQFIATPVMNDLATGDVCVVTGYSGAVLVAARRAAEAKNGQQIVYSLPSAGAPFWFDSMAIPKGAAHADHALRFIDYILRPDVVAKISNKVMYPNPNRVATPLVDRRLTANPAIYPDAATMRTLWVKRPMPPQAMRMQTRYWTRFKTGY
>NZ_CP004379.1|WP_004536006.1|424212_425325_-|histone-deacetylase
MIPTGLLFDPAFLSHRQGDLVYVVPHGTLNLGEHFDSSLRLAYTKQLLDAVGMTERLTRVAFARATDEQLLRVHRPEYLRQLAEACAVAGEQVVRLGDDAAGSASTEDVARLAAGAACAAVDAVMTGPLRQAYALIRPSGHHAGADFAMGYCYYNNVAIAARHAQAAHGVERVAIVDWDVHHGNGTQQTFYDDPSVLFVSLHEAANFPVDGGEARETGGGAGAGYNANVPLPSGTGDAGYRHAFDELVLPLVEAFAPQLILVSAGQDANAFDPLGRMRVQRDGFRHMARALRQAAGGACGGRIVMLQEGGYSLPYLPIATLGVLEGLVGWNAPFDDPHQFVQYPLGEGERAAVKAARAALAPYWPTLHRS
>NZ_CP004379.1|WP_004189258.1|423326_424202_-|N-carbamoylputrescine-amidase
MRKTTVAVTQMACDWNVDANLSRAERLVRDAAARGAQIVLLQELFETPYFCIDQHPAHLALAQPYEGHPWLMRFASLARELGVVLPVSFFERAGQTQFNSVAIFDADGRALGIYRKTHIPDGPGYTEKYYFTPGDTGFRVWDTAYGRIGVGICWDQWFPECARAMALAGAELLLYPSAIGSEPHDASIDSRAHWRNAQRGHAAANLMPVAASNRVGVERGASGEIVFYGSSFIAGADGEMIVECDRHGEAIATAEFDLDALAYRRRGWGVFRDRRPECYRALSEGAADRVR
>NZ_CP004379.1|WP_024428817.1|422725_423190_+|hypothetical-protein
MEFRPIKESDLGSTYDIRFSVTENRILPHQIHLLERDRVLEQLRSGFGVLAIEGDAAVGYCTAAGLGGPGKRSWRTAPKHCHAGPRRLRERAALAAAAPMAARSRPRGCVTCKAPSAERRSPSETSCASARTGRRAPFGRFSAFAAHRQAGRRH
>NZ_CP004379.1|WP_038742490.1|421235_422327_-|phage-portal-protein
MSSWRRRASTTAPSACSNVTSSAATTLRNRPRQIRAPARAEVFTFDDPTPVMNRAEILDYVECWSNGEWFEPPVSFAGLAKSFRASTHHSSALFFKANVLASTFRPHRWLSRHAFERWALDFLTFGNGYLERRRNMVGGTLRLEPALAKYVRRKADFSGFVYVNGWQERHEFEPDSVFQLVRPDINQEVYGLPEYLSSLHSAWLNESSTLFRRKYYENGSHAGFILYMTDAAQKQDDVDKMRDALKNAKGPGNFRNVFMYAPGGKKDGIQLIPVSEVAAKDEFFNIKNVTRDDLLAAHRVPPQLLGIVPSNSGGFGTPDTAARVFGRNEIRPLQARFAELNDWLGDEVVRFDDYEIPLAPVAA
>NZ_CP004379.1|WP_004523107.1|420877_421162_+|hypothetical-protein
MKTIGRILLALVLTWPLLTGISSLPLLTHWFANGGEGWNALSPVFRALGSDGGEQNEEIFVGILLVISFVLALVLSFALFGLVDRLRHSTDRRA
>NZ_CP004379.1|WP_004200731.1|420398_420881_+|DUF2778-domain-containing-protein
MPAECTFVLNRSRLSTLTCPGFGSVPAFSGNGRYINDPGSTAVADKGPLPAGVYYIIDRQSGGHLGWFRDTVMDAALNTYRAEWFALYRIDGQIDDWTIVNGIRRGHFRLHPVGRLGESDGCITLTSRGQFDKLRAFLKAQPTTQVPGTSFRAYGKVTVK
>NZ_CP004379.1|WP_004553744.1|418856_419861_+|hypothetical-protein
MAQKKKVVYFLGAGASFGAGAKATVQAGHQLPIPTQATFRPTFLRFCKSQKNRARIESFLFRYFLGYGKTPVRTPAAKRRHLLTSIDVEEVFTFLSERTRAPSTSTQLRTYALQVWGALAEEIGQVFSRFNANSATKAIYKDFLKHHFRRFDTVVSFNYDTIFENSLPARRSARYVGLRDSAGTIPLLKPHGSVNWVQADDGTITVGNPVGPAVIVAPTHLKFIADPDQKEVQHPGYLDQAHEIQKIWAEMEREMRFARSLVFIGYSFPVADLYFASVLRSVLADRDTTPNIVIVNPDAVAISERLLRRFPLVTVSRFFDLAQFIRAGRAVIAQ
>NZ_CP004379.1|WP_154218334.1|418386_418755_+|hypothetical-protein
MLLLPAANSDAPLPPEHCLRRFLYAPPPFKINALRDSQSANPRLIKVNPGHPSTPELSFHCTAQAATSSATCPTNPPRTAPLTRSFAAIDYKAPEIPSTFNNLDKYRVSKTIDCKGFGALSG
>NZ_CP004379.1|WP_004525837.1|428798_429347_+|hypothetical-protein
MEEAYARRALLLHLGSVLQILSRLEGAPDNQSIEALLAANGMLADVPLVEYVVQDMTVREFSARALRAFCLWPQLLLEDPLDCAALALPVRKHLFAGNDAGWKAYAATLREVSPGFDTARSYAAEPHEAEFDLADERDAETGDGPVERDDEADDDGRLRERAAASVESATPAGAPVRRESYE
>NZ_CP004379.1|WP_004553742.1|429609_431058_+|RNA-polymerase-sigma-factor-RpoD/SigA
MKVSARELRYEQGIDRLLELAGARDDTEYADVADEFASAPSSAFAHDLGEPDSLDHQASDESAGAGSFGDKPTRPAHGDTDVDTDWRDDDAPPSGSNDAAPVDTTASTDPLALFVRRMHAVPLLTHAQEIALAAEIEAGREQMLQALAEALDRLDLASLPADPALGRARAALQRARARGDEGARAFARARTAAYAALAAHGWPSAEVDAVRRAMRRLPTSPEKSDAGAQRAFADGEARISAATARMAEANLRLVLSIARKYASRGLDLADLLQEGNLGLLRAIEKFEHRRGFKFSTYATWWIRQAISRAIADRARTIRVPVHVGDEARRVRKAADRIERRSGVSASLAELSEATGLPAERLRAVLTLPREPRSLNAPLGDDDQAEFGDIVEDTSTPSLFDALAHGQMCDVVTSLLKTMSAQEADILRRRFGIGGDEPWSYEQIAARAGVSREQVRRIEKRALQTLRVTAEACNAHDFLDVQP
>NZ_CP004379.1|WP_004545670.1|431076_432690_-|glutamate--cysteine-ligase
MPNNMTSRQTDLLQQRLAVLSTSPTREQLPDGLRGIEKESLRVTRDGMIAFTPHPRALGSALTHPSLTTDYSEALVELITPAERDAATTLERLDELHRYVYASLGDEMLWTDSMPGLLPADDEIPIADYGTSNIGRLKTVYRRGLAYRYGRTMQCIAGIHYNYSLSEEVWRRLHAEEGSTAGIVDYQSERYLALIRNFRRTSWLLMYLFGASPALDAGFLRGRAHKLDTFDAATLYRPHATSLRMSDLGYSNTTAQAALQADYNTLSGYLDALSKAVSEPYPPYEAIGTHRDGEWIQINTNVLQIENEFYSTIRPKRVTYSGERPLHALASRGVQYIEVRCLDIDPFEPTGIALDTARFLDAYLLVCALDESAPLTCDAYRESNANFGRVTMEGRKPGLELTRDGAAVPMRAWADEIFAQIEAAGRVLDDIRGDDAHARAIAAQRAKLDDPELTSSARVLRAMRENGQSFLEFARAQSAAHAAYFHGRPLDEAATRDARALAERSLAEQAELEGKNAGSFDAFVAAYRAYTLNRFSV
>NZ_CP004379.1|WP_004553741.1|432848_433790_-|DNA-3-methyladenine-glycosylase-2-family-protein
MSAAVEPAAVRPDSVVLELPFKSPYDWPRVLRFFAGRAIPGVEAVGDGAYRRTVDHHGAIGTLTVRKHPRKRCLVALVEGDAARHADAAFAARLSTMFDLQADPAAIGAHLARDAWFAPLVGAAPGLRVPGAWSGFELIVRAIVGQQVSVKAATTIVGRLVERAGERLAPHAPGAIGWRFPEPAALAACDVSRIGMPGKRAAALQGVARAVASGDVPLEAYASDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVARDPALDRPASQRLRADAWRPWRAYAAMHLWNEIADRAGSARGG
>NZ_CP004379.1|WP_004553740.1|433786_434881_-|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada
MKQPPYPTDDARWAALVARDVDADGAFCYAVKTTGVFCRPSCASRLPRRENVSFFADTGAARAAGYRPCKRCRPEGLPRELDIVNRACAVLDAHRQDRFTLAQLSDAVHVSPFHLQRLFKRVVGVSPRQYQAAQRGAALRDALQSGAAVTRAAVDAGFNSPSRLYESVPRELGMSPSAFRRKGAGLKIDYATADTRLGVVLVAATSKGICKIAFGDAAAPLVDELRTGFANAQIAESPERIAPFIAQVDAYLNGTRRRFELPLDLAATEFQQRVWDALRRIPYGETRSYTQIAEALGAPRAVRAVASACASNPVALAIPCHRVVQKGGSLAGYRWGLPRKAALLDAEARRAAGESVESAVDHAA
>NZ_CP004379.1|WP_004197761.1|435282_435699_+|lactoylglutathione-lyase
MKFHIHEIDHVVLRAADLAAMTRFYCDVLGCHVEKEQRELGLVQLRAGRSLIDLLAVGAPIDRAGSGAPGKGRNMDHLCLRVEPFDAAALRTHLAAHGARPGDEARRYGADGYGPSLYLFDPEGNMVELKGPPEAVAP
>NZ_CP004379.1|WP_004530511.1|435866_436421_-|YaeQ-family-protein
MALKSTIYKAELQIADMDRHYYADHSLTVARHPSETDERMMVRIAAFALFAHERLEFCKGLSDTDEPDLWQKDLTGAIEVWVDVGQPDERRIAKASGRAGRVNVIAYGGRTSDIWWQGARGKVERLRNVQVTTLADGVAAALGGLAERTMRLQCTIQDGAAWLSSATHDPVAIEWTTLKAREDA
>NZ_CP004379.1|WP_004525830.1|436636_436984_-|hypothetical-protein
MLKRTGLFLALTGGIVAFSVAQANGDASLKPQQEIQLTKNAWGCLSKDNLDSVLNHERDGKAQAKQQYFDDYRCLSVPEGQRFRVVSVDKGDVQFVSAENSDQQGLWTDARFIKQ
>NZ_CP004379.1|WP_004524603.1|437470_438031_-|spermidine-N1-acetyltransferase
MQIQNEQHTLALRPLERQDLRFVHELNNDAKIMRYWFEEPYETFTELSQLYDQHVHDQRERRFVAFDSDGELVGLVELIELDYIHRRGEFQIIIAPNRQGRGFATRATRLAVEYAFKVLNLRKLYLIVDKSNVAAIRVYEKCGFKHEAELIEEFFGNGQYHNALRMCIFQRDYFAAQPGAELHARE
>NZ_CP004379.1|WP_004553737.1|438924_440082_-|DUF4382-domain-containing-protein
MKTIWKFFGLAAAVSVLLAGCGGGGDNSGQTGTLHVAMTDAPSCGFDHIYVTVAKVRVNMSAQAGDNDSGWTDVALAAPQKVDLLSLTNGVLADLGQNALPAGQYQQVRLVLAQNQGNTLANSIVPTDGTEQPLATPSATQSGYKIITPFTVQPNTLVDLVLDFNACKSIVQRGNGTYALKPVVTATPTVVSGAIDGYVSPTEAGATVYAEQNGHVIKGTLADSTGHFVLTPLVQSSTNGNYDIVITQNNVSTGIVRSVPVVVNTTTSVSTSSAPITLPASTMNMVSGTATASADAILRALQMVNSLPYEIASTNANLDTGAYALTLPTAAPIVGTYSGSLPVAMSAAPSAAGQYTIEADAANGATQQQPANITAGSVSNVNFGF

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Crispr_ID: NZ_CP004379_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP004379_2

1327796-1327948

Orphan

Consensus_repeat	Method
CGGCGGCGGTGGCGGCGG	CRT

3 spacers

The CRISPR arrays of NZ_CP004379_2

>merge|NZ_CP004379|2|1327796-1327948|CRT
GGGCGGCGGTGGCGGCGGCGGTGACGACGGCGGCTACGGTGGTGGCGGCGGCGGTTACGGCGGCGGCCGGGACATGGAGCGCGGCGGCGGTGGCGGCCGTGCGTCGGGTGGCGGCGGCGCGGGTGCGCGCAGCGGCGGCGGCGGTGGCGGCGC

>NZ_CP004379|2|1|1327796-1327948|CRT
GGGCGGCGGTGGCGGCGG	CGGTGACGACGGCGGCTACGGTGGTGG
CGGCGGCGGTTACGGCGG	CGGCCGGGACATGGAGCG
CGGCGGCGGTGGCGGCCG	TGCGTCGGGTGGCGGCGGCGCGGGTGCGCGCAGCGG
CGGCGGCGGTGGCGGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP004379.1\|WP_004522854.1\|1316320_1318330_+\|sodium/hydrogen-exchanger-family-protein	unknown	unknown	gnl\|CDD\|235131
NZ_CP004379.1\|WP_020850417.1\|1318413_1318977_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NZ_CP004379.1\|WP_004541081.1\|1319697_1320555_+\|DUF4743-domain-containing-protein	unknown	unknown	gnl\|CDD\|239648
NZ_CP004379.1\|WP_004530929.1\|1328123_1328855_-\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223489
NZ_CP004379.1\|WP_129195167.1\|1334239_1334692_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_004530934.1\|1319070_1319685_+\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NZ_CP004379.1\|WP_004522845.1\|1330967_1331219_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_004553790.1\|1326153_1327341_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341025
NZ_CP004379.1\|WP_004553788.1\|1329198_1330779_+\|hydrolase	unknown	unknown	gnl\|CDD\|293817
NZ_CP004379.1\|WP_004553787.1\|1332178_1333948_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_004200146.1\|1314670_1315210_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|224692
NZ_CP004379.1\|WP_004553786.1\|1335141_1336671_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379114
NZ_CP004379.1\|WP_004522850.1\|1320606_1321488_+\|formyltetrahydrofolate-deformylase	unknown	unknown	gnl\|CDD\|235676
NZ_CP004379.1\|WP_076851601.1\|1337182_1337404_-\|carboxymuconolactone-decarboxylase	unknown	unknown	unknown
NZ_CP004379.1\|WP_004195206.1\|1315209_1316193_-\|KpsF/GutQ-family-sugar-phosphate-isomerase	unknown	unknown	gnl\|CDD\|182814
NZ_CP004379.1\|WP_004522844.1\|1331391_1331709_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP004379.1\|WP_004553785.1\|1337400_1343487_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377060
NZ_CP004379.1\|WP_004526066.1\|1323072_1325940_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP004379.1\|WP_004535627.1\|1336780_1337131_-\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|367130
NZ_CP004379.1\|WP_004540904.1\|1321786_1322872_-\|membrane-protein	unknown	unknown	gnl\|CDD\|223701

Protein	Function_ID	Function_description	E-value
NZ_CP004379.1\|WP_004522854.1\|1316320_1318330_+\|sodium/hydrogen-exchanger-family-protein	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	1.57079e-95
NZ_CP004379.1\|WP_020850417.1\|1318413_1318977_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	3.50645e-93
NZ_CP004379.1\|WP_004541081.1\|1319697_1320555_+\|DUF4743-domain-containing-protein	gnl\|CDD\|239648	cd03676, Nudix_hydrolase_3, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	7.21652e-81
NZ_CP004379.1\|WP_004530929.1\|1328123_1328855_-\|dienelactone-hydrolase-family-protein	gnl\|CDD\|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	3.3452e-47
NZ_CP004379.1\|WP_004530934.1\|1319070_1319685_+\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	3.41893e-42
NZ_CP004379.1\|WP_004553790.1\|1326153_1327341_+\|MFS-transporter	gnl\|CDD\|341025	cd17472, MFS_YajR_like, Escherichia coli inner membrane transport protein YajR and similar multidrug-efflux transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli inner membrane transport protein YajR and some uncharacterized multidrug-efflux transporters. YajR is a putative proton-driven major facilitator superfamily (MFS) transporter found in many gram-negative bacteria. Unlike most MFS transporters, YajR contains a C-terminal, cytosolic YAM domain, which may play an essential role for the proper functioning of the transporter. YajR-like transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.72558e-122
NZ_CP004379.1\|WP_004553788.1\|1329198_1330779_+\|hydrolase	gnl\|CDD\|293817	cd07731, ComA-like_MBL-fold, Competence protein ComA, ComEC and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes proteins required for natural transformation competence including Neisseria gonorrhoeae ComA, Pseudomonas stutzeri ComA, Bacillus subtilis ComEC (also known as ComE operon protein 3) and Haemophilus influenza ORF2 encoded by the rec-2 gene, as well as Escherichia coli YcaI which does not mediate spontaneous plasmid transformation on nutrient-containing agar plates. It also includes the phosphorylcholine esterase (Pce) domain of choline-binding protein e from streptococcus pneumonia. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. .	1.84159e-05
NZ_CP004379.1\|WP_004200146.1\|1314670_1315210_-\|HAD-family-hydrolase	gnl\|CDD\|224692	COG1778, COG1778, Low specificity phosphatase (HAD superfamily) [General function prediction only].	1.33155e-78
NZ_CP004379.1\|WP_004553786.1\|1335141_1336671_+\|AAA-family-ATPase	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	1.18471e-08
NZ_CP004379.1\|WP_004522850.1\|1320606_1321488_+\|formyltetrahydrofolate-deformylase	gnl\|CDD\|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	0
NZ_CP004379.1\|WP_004195206.1\|1315209_1316193_-\|KpsF/GutQ-family-sugar-phosphate-isomerase	gnl\|CDD\|182814	PRK10892, PRK10892, arabinose-5-phosphate isomerase KdsD.	1.26452e-136
NZ_CP004379.1\|WP_004553785.1\|1337400_1343487_-\|hypothetical-protein	gnl\|CDD\|377060	pfam03534, SpvB, Salmonella virulence plasmid 65kDa B protein.	8.57854e-17
NZ_CP004379.1\|WP_004526066.1\|1323072_1325940_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP004379.1\|WP_004535627.1\|1336780_1337131_-\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|367130	pfam02627, CMD, Carboxymuconolactone decarboxylase family. Carboxymuconolactone decarboxylase (CMD) EC:4.1.1.44 is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins CMD represents the C-terminal domain, pfam00561 represents the N-terminal domain.	1.95582e-17
NZ_CP004379.1\|WP_004540904.1\|1321786_1322872_-\|membrane-protein	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	1.94626e-15

>NZ_CP004379.1|WP_004553790.1|1326153_1327341_+|MFS-transporter
MSNPSATSTRMSAPELRATTSLAAIFALRMLGLFMIMPVFSVYAKTIPGGENVVLVGIALGAYGVTQSLLYIFYGWASDKFGRKPVIAAGLLIFALGSFVAAFAHDIAWIIVGRVIQGMGAVSSAVLAFIADLTSEHNRTKAMAMVGGSIGMSFAVAIVGAPIVFHWVGMSGLFAIVGALSVAAIGVVLWVVPDAPRPVHVPAPFAEVLHNVELLRLNFGVLVLHATQTALFLVVPRLLVDGGLPVASHWQVYLPVMGLAFVMMVPAIIVAEKQGRMKPVLLGGIAAILIGQLLLGVATHTILIVAAILFVYFLGFNILEASQPSLVSKLAPGSRKGAATGVYNTTQSIGLALGGVVGGVLLKHGGPDTVFFACSALVAVWLIIAAGMKQPPRKA
>NZ_CP004379.1|WP_004526066.1|1323072_1325940_-|excinuclease-ABC-subunit-UvrA
MEQIRIRGARTHNLKNVNLDLPRHKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQLMEKPDVDLIEGLSPAISIEQKATSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPDHEIPLEAQSVSQMVDAALALPEETRLMILAPVVANRKGEHAELFDEMQAQGFVRFRVRSGGGAANEGAAKIYEVDSLPKLKKNDKHTIDVVVDRLKVRPDMKQRLAESFETALRLADGRAIALEMDTDREHLFSSKFACPICSYSLQELEPRLFSFNNPMGACPECDGLGQITFFDPKRVVAHPSLSLAAGAVKGWDRRNQFYFQMLQSLAAFYDFDIDTAFEDLPEKIRKILLYGSGKQTIPFSYINERGRTTIREHVFEGIIPNLERRYRETDSAAVREELAKYQNNQPCPSCDGTRLRREARFVRVGQGDYARAIFEVSSWPLRDALGYFDGLTLDGAKREIADKVIKEIVARLTFLNNVGLDYLSLERSAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLIGTLKHLRDLGNSVIVVEHDEDMIRTADYVVDMGPGAGEHGGMIVAEGTPKQVQANGDSLTGQYLVGKRTIEYPDERISPDPQRMLRIVDAHGNNLKHVDLDLPVGLLTCITGVSGSGKSTLINDTLYNAVARHLYGSATEPAPHESIEGLEHFDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPASKERGYDPGRFSFNVKGGRCESCQGDGVLKVEMHFLPDVYVPCDVCHGKRYNRETLEVQYKGRNISEVLDMTVEHAYEFFSAVPVVARKLKTLLDVGLGYIRLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIALLLEVIHRLRDQGNTVVIIEHNLDVIKTADWVIDLGPEGGAGGGQIIAQGTPEQVAKTKASFTGKYLAPLLKRKK
>NZ_CP004379.1|WP_004540904.1|1321786_1322872_-|membrane-protein
MEKPSEPTREPQAREPHLRSVRLTSDFSLPKLSAIEIGSYLLALFGLWLVLHLKLLGGLLAGLLVYQLVHMIAPAIERHMSSQRARWVAVVLLSTAIVGGLAGLTIAVIEHFEHTVPNAQNLLGQVMQIVDQARTRTPEWISNLLPVDAEQMRAKAAGLMNRHMDQLQQGGKSVARGFGHVLFGMIIGAMIAIGIDRHKLRQPLSTALVARISRFSDAFRRIVFAQIKISALNAFFTAIYLLVALPIFHQRLPLSKTLVLVTFIAGLLPVVGNLISNTLIVAVSLSVSMGTAIASLVFLVVIHKLEYFLNAKIIGGQIESRAWELLLAMLVMEAAFGVPGVIAAPIFYAYVKRELIYLRLI
>NZ_CP004379.1|WP_004522850.1|1320606_1321488_+|formyltetrahydrofolate-deformylase
MPADHSFILKLSCPDRRGIVHAVSGFLLERGSNILDSAQFGDSRTGEFFMRVHFEQAGACGAAAALDALRAEFAPLAEAFAMRWELHDAAVKPRVVILVSKIGHCLNDLLFRYRTGQLPIEISAIVSNHKDFYQLAASYDIPFHHLPLAAGASADAKAAQEARVLEVIDGHAADLVVLARYMQILSPALCERLAGRAINIHHSFLPSFKGAKPYYQAFDRGVKLIGATAHYVTTDLDEGPIIEQEVERVDHSMTPDELTAVGRDVECVTLARAVKWHVEHRIVLNGTKTVVFR
>NZ_CP004379.1|WP_004541081.1|1319697_1320555_+|DUF4743-domain-containing-protein
MTFACIAAARRFDAAAHVPFAIAGRQVGWLRRGDVARLARWPDVFEFPAGRVELAARYDSVDARSMALASPIGALAAEGAIVGWRDEIYAIRNRFDDPPLAYIERAASRFFGTMTYAVHLNGIVEYAPSAPLAMWLGRRSATKATDPGMLDNVVAGGIGWGLGIEDTIAKECWEEAGIAAELAARAIPGRVAHVLRSLPEGTQAEQIFVYDLPLPRDFVPHNQDGEVAEHLLAGVDEIVAWLRAGEATVDASLAMLDSLLRHRAIAPEDARGIDVLFAPPPPGLG
>NZ_CP004379.1|WP_004530934.1|1319070_1319685_+|LysE-family-translocator
MPNFMLFLATSIAITVAPGPDNLQVLARGISQGRAAGIVAALGFASGVLFHTTLAAFGVAALLRSSPVAFHLLKLAGGAYLIWIGIKALRSKGLATAHARAPQPLSTIFRQSVIGNLLNPKVTLFFVVFLPQFVDPHGAQPVALQMLELGALFMAQTAAVFSVFGVGAGAIGVWLKRRPRVGVWLDRLAGATFVALGLRVALKD
>NZ_CP004379.1|WP_020850417.1|1318413_1318977_+|adenine-phosphoribosyltransferase
MMSTSDAPLDPVEFIHSRIRTVPDWPQPGVMFRDITPLLQSAKALRVLVDLFVERYVDAKLDYIAGLDARGFIIAPIVAYELSVGFVPIRKVGKLPYATQRESYALEYGTATVEIHEDACKPGDRVVIVDDLIATGGTMMAGKNLLERLGAVVVEGAAIVDLPDLGGSALLREAGLPLYTVTEFPGH
>NZ_CP004379.1|WP_004522854.1|1316320_1318330_+|sodium/hydrogen-exchanger-family-protein
MISPLEMTLLLLLASVVGVVVFRSLNLPPMLGYLTVGILVGPHALGFAADLERAEHLAEFGVVFLMFSIGLEFSLSKLRAMRRLVFGLGLAQVLGTIAIALVLGALFERWMHITWEGSVALGGALAMSSTAIVSKMLAERLEIETEHGRNIFGVLLFQDLAVVPLLIVIAAFGGESSKDLAMSLGFAAVKIVVALALLLIVGQRFMTRWLNVVARRRSQELFVLNLLLVTLGAAFITDRFGLSLALGAFIAGMLISETPYRHQVEEDIKPFRDVLLGLFFVTTGMLLDPSVIWRHPLLVLAFFVGQVLLKSVMITGLARAFGATPGVAMRTGLGLAQAGEFGFVLLNLILDRHLVDATLLQSILASMLLSMLAAPFLIQNADRIVMRLSAAEWMQQSLQMTRIATQSIKQKGHVIICGYGRAGQNLARMLEQEGIAYVALDLDPDRVTAAAAAGESVVFGDAARRESLLAAGIHRAAAVAVTYANTPSALRVLHNVHELEPTLPAIVRTVDDADLEKLLAAGATEVIPEIVEGSLMLASHTLVLMGVPMRRVVRRVEEMRDARYSLLRGYFHGADDADDDDHEQVRLQSVPVDARADAVGRSLSELGLFALGLEVTAIRRHGIRGVEPDPETKLRASDIVVLRGLPEALAQAEERLSRHRREGGSAAVA
>NZ_CP004379.1|WP_004195206.1|1315209_1316193_-|KpsF/GutQ-family-sugar-phosphate-isomerase
MIAKINDDRALALARDVLDIEANAVRALAEQLDGEFVAAVGLLLNCRGRVVVSGIGKSGHIARKIAATLASTGTPAFFVHPAEASHGDLGMVTKDDVFVAISNSGESEELVAILPLIKRLGAKLIAMTGRPASSLATLSDVHLNAGVAKEACPLNLAPTASTTAALALGDALAVAVLDARGFGSDDFARSHPGGALGRRLLTYVRDVMRTGDEVPAVPLDATLSDALFQITAKRMGMTAVIDDANRVAGIFTDGDLRRVLERDGDFRRLPIVDVMTRHPRTIAPDHLAVEAVELMERHRINQMLVVDERGALIGALNMHDLFSKKVI
>NZ_CP004379.1|WP_004200146.1|1314670_1315210_-|HAD-family-hydrolase
MSAPPATAAERASRVKLMIFDVDGVLTDGGLHFTAAGDAMKSFNTLDGHGVKLLGEAGIATAIITGRRSEALAARAKEMRIAHLHEGVENKLAVFGELLRALGLEPGECGYMGDDWPDLAVMLRCGFAAAPANAHPDVIARAHWVAEARGGHGAVREVCDAILRAQHRYDALLAAACGA
>NZ_CP004379.1|WP_004530929.1|1328123_1328855_-|dienelactone-hydrolase-family-protein
METRSIAYDCGGARLTGYFADDAPNTKKPAVLIAHEAFGLNEHIRARARRLAELGYAAFALDMYGAEGFPMPEAIRRHIELMSTPGLMHARASAALSVLMEQPGVDRERVAAIGFCQGGISALELARGGAPIRCAVGFHPGLMRPAGSQDGPIRAKVLMMIGARDPDVPAADQAAFAAEMQEKQVDWQLHLFGGVGHAYTNPDADGWNKPGYGYSRAADQRAWMMMLALFDEVFGGAAAVGKA
>NZ_CP004379.1|WP_004553788.1|1329198_1330779_+|hydrolase
MNPFFGAQREWQDVPVPARAYARLDNLHLPHADAPDRRAALRFDLIDADWLDNQAGADNPLFDLGRPHRMRAAWKRWFAAARGGDADDPFRAAPLYVLEVSVPFDAREWRKRLGLTREAMANDAHGEILAAFRRRWYELTVLREADARAGAMLGLLHRGIADEGLRVCCFAALAPAAHAAGLTALGTLAGSPALTSASLKPLVRDVRATYLGVYDVGQANANALLGGIRGRDLHGVVRHGVFPTLYFDLGMPLQSQRHTAPSNVRFCFTAEPPIVLSHWHDDHLGGVALPTAAGCPTSQQMDWIVPDYSLATRHKALVTAIWAAGGSVHVFSASPAGRRLQAATASGHLLTLTRGTARDPNNGGIVMQVSSAQQQARRFADPPRSWLLPGDCDYKHFPSTFTPTNVIALVAPHHGADLGKGSVPVPPAAGGYLRLVYSFGRDNKYQHPRQGFVDAHHVAGWTHPVVPATGAITCVSGDDVRTTNVHSPWSAKPRGVLVGWSKAPHSVSACTLGGGATNCTLPLAKV
>NZ_CP004379.1|WP_004522845.1|1330967_1331219_-|hypothetical-protein
MRLIEPNEHAGYLAALHARGLSGNEFTLRETDTTDPKGDENIGQTGFVTITRHSTHATREYPLGDAGDWLQHFKKDLEAGAFD
>NZ_CP004379.1|WP_004522844.1|1331391_1331709_-|hypothetical-protein
MIAPDPESTFRGLPLTPEQNAEVMHYIKVRTQRGLPWDTPELEAMIRDMMLPPEDEAADSDFLSDEARAVAERAMSSVEDEMDPIEAREEWRAAMEAENMKGLRR
>NZ_CP004379.1|WP_004553787.1|1332178_1333948_+|hypothetical-protein
MNEAWILQASEIRRPFSRATWVPLRASLNDEKGSVTEVGYVSDVFACGSVAFPKRHRELAERLSWSDIGTGHTVAPYAYSDGHYSPIDVYQYNDKEPVGVNLVFEHPQPVVGGRQWILNPDLVVALRLIKEGPNWVRPEEDFVVVSRETVDSDGSHRLIEIKREFLIDYLAARGLFLRLSYYRQRVENVIDLKDSPYVGLNEIQEQREGGRYELRIRELNAVFGGSWASFRMWRTDVDEEEDAPVMGPETNDNTASESARGHRSGYPGVRVEGEFWRDEWIEHQEKSTRVRGDEDQNLPYFIADTDGSRKFSAELNDEDIGRWLWFRTSVVNELLSHRGFSLEWYTAETGAIKSTSGYSTHFGINASELITVYAYDIAKLPAWEQFLWAANNVAPEGKVSAELLASQVKAQPADTHAVEEMLFRGMRLLETDFRKTFGVSLYSHEIDDVASMQHVSRFSSKDQASLLRLAKELVRIFSDRLDVRSLRKLSNHPDKEKLGSNKLLQNILAQKAGEACAREVFAAIAGAYDMRLGDAHPTSSKIGEALRLAGIDTSVSYLRQGEQLIHNFGYALWCTGSLLFEGHEKSEEK
>NZ_CP004379.1|WP_129195167.1|1334239_1334692_+|hypothetical-protein
MDPNDLLSHQRQENKEIVRRELFYSSTEKTEDGWYNAEAGVGVQLNDGKTKGLNPNISDKPSRDAGLLKGPNVSAQAGVGDGKVGAFANAELFRLSAANSWAQGDIAFSLRTGAQFGAHNELKIAGTGLEIGKNGIGLSILRVGFKIKPW
>NZ_CP004379.1|WP_004553786.1|1335141_1336671_+|AAA-family-ATPase
MPNTIEINNLKHIHTLAFEVPPPGVHLLSGSNGAGKTSVLACLRRIGHPNAFAQHFRPSQISDALDSFDGAEIVYTVNGRRVTYAYAGERWVPRPRSANRLLQNFGYPTVVYVGATADRITPRPEDFRPARIRPAPQVLRDAANEILETNKFDALKVINLTPGGGNPAFVLQTKAPPQAKYVSERNLSLGELCVMKLIRSLLTCANNSLILIDELELALHPRAQIGLLRYLQTIAQDKQLTIIFSTHSVSLLKRVPRDRIIFLEADDGNVSAIKGCFPTYALGNIAYDEERGPDLVIYVEDEAALYATEALTQLAIGHRFRNDESLFPTVHVIPIGPFMSVVRFLDRSRALLPISCTSVALLDRDVKDETIANWEAERNHVALAEFQRHEQTIDYLPWTPEVAFVDFLRNHRQTALRLIQQYFHNVHLNYGNADIGDIPAAAGSEQRNRCKTAFRNVVARIAGALPNDSEADVRKALIRLFAQWYWDNERAAVLQLVGPHLAAAMRRQQ
>NZ_CP004379.1|WP_004535627.1|1336780_1337131_-|carboxymuconolactone-decarboxylase-family-protein
MALPQSYRELTSEVATQMRALRKTQPDLMSAFAALAAAGTKEGALGKKTRELVALGIAIASRCDDCIGFHVQTLVKLGTTREEFEDLLATAVYMGGGPSMMYAAHALRAVEEFGGE
>NZ_CP004379.1|WP_076851601.1|1337182_1337404_-|carboxymuconolactone-decarboxylase
MRIAADQIAADRLSYARRRVRSVSGACVWVSRGMARPHVKDRTESACRRGRFDPGQRRCRFDAPMRLRAERDS
>NZ_CP004379.1|WP_004553785.1|1337400_1343487_-|hypothetical-protein
MAKTSGTADEILNLPSGGGSVSGDGGDFSIDLNTGTATLKFDLTVPAGPNGITPPHTLQYSAGAGDGAFGIGWSLGLMTIRRRITPATGAAEPAPPGACSLVGVGELVDMGARRFRPIVDATGLLIEFTGASWTATDKTDTQYTLGTSANARIGGGALPAAWLVDRCADSAGNAIAYTWLDVGGARVPQAIAWGTYRLDFVYEARPDVLVDGSYGAPVTLDKRCARIELHATTEAPSLVRSWTLLYDDGGGRGRSLLATIREQGHAADGSILAAPERTFAYSSPGAPALVPVTGWTTPLSDPNTDLVDLNGDGLPDIVHLGHGMPTMHPNLGGGQFGAPRPLARTAAPLRLSAPSVAFADMSGNGSVDVLVLDAPFSGYYPLAAPGGSAPAGFGRPIVFERAPAVSPSDVRLRFVDLNGDGITDILLDTGRGWLAYLRDGPASWSDAPRVLPPARTPPVSLADPHVHLADMTGDGLMDIVRVTGSGLTYWPARADGGWDAAIAMTPSPAFGRDFDPHRLALYDVDGDGCADLVYVGLQSVTLWRNVGATRLAAPVAIPGTPVALPGSYRIVDLLGSGTAGVHFQLPSIAGASRQSYLDLGGGVKPYLLTDLAHGAAQSTHIGYRTSTEYARDDAHAGAPWRTYHPFPIQCVARTDQTDHGTGATTSTRYAYHDARYDPATRTFLGFGRVDSEQLGDASCPTLRVETTFHLGLDPARPLTGDEALKLGALRRKPLVTATYGLDGSPLEHRPYSITRHAYDALLVASTADNGKRIAVPYCTTSTEERWERQSAAVSARTVDYLAITSEGDVTSQRTRAQRAGIAAPDQDVTTTTTLATGGKNLRLPARVTQTAPGGDIVSESICFYDGDAFAGLPEGQATRGLVTRIEDRVFDDAFVASVWGDTPPDLTQYGYHRLPGEAGSWWKTRRAHARGANASGPTLATKGPLGALQTLQYDASGQRVVKVIDALGNAVAATTDARVFQTASLTDANGHRTADAFDALGRVVATIGPLDTPALPTIAFTYTVGAISTVTSATRGTHGGADAVPALTWIDGTGNVLGKGTPAAAPGEWTVTHAVRRNARGLVAASFLPYAATGANWQPPPADTGATTSTYDALGRLVQLTRPDGLVVTSRREGDTLITSETWPGGAALDVERQVYDAAGQLVSVSRNAGDHWVEQRYAYAPSGKVRDVTLPGGAHVAFTLDLLGRVFAQQSPDTGRTVFLLDASDNQRARTNAAGQIVRTEVDAMNRATNVYHDAEPAPRVRYEYADASGAPPADGIVANRYTRLWRITDEIGTVDFEYDEAGRKTATTRTVAATGQRFVTRRAYDALGRLARATLPASAPGGAARTIAYGYAADGRLVSASGVVKDAAYDRFGRLSSIDYENGASTLIDYAANAGGIARVRVLDAARNVLRDTTLTRGGGLVQTLASAHAGDDSVDFGYDPLRRLTSAHYRQGATAADAHDWTFDDAFNATAATDAGVLTYEPGTHRLASVGGAAVAFDAAGRMTSGRFGAATFDAADHLSAVTLPDATHIAHTYDYQGRRVRSTKNGAQTYFSPIEDIEFQGDTAIVWITFGRQRIAADIGGALTFVHPNALGVMDLITDSGGAYGTRVRQTPFGYARAADGAAPAGGVAAVALALGAADATGLVCHGLRWYDPRVGQFISPDPVVTSVYTVGAWNPYVYCLGNPILLADPNGCSFLSVLEIIGVAILAAACVVGAIFTGGATLVALGVLSANIGGWLLAGVALGSLGGAIAGELAAQKAGGNLWAGAFLGAFLGGATSLIGGALGGAAAAGIDTLIGGTKTFLSFVAAGAIQGTLAGAGTGLAIGYAGGKGNAESMLIAMAKGAAWGAVLGTLLGAGIGAIAGTGISGAAKPDNFLNIGAFGQKFADFTSTSTAINSADNAAGVTESLAQLSMPNGFNAGNLLGLLPNLVTTNEQAAGWFSIPIGWLGPGVLNDAGFAGLVDTSMALDQAGFSYAHQISLLLGAAPYFIDYAATMAQIVDANGVNNFEMAFNNAFGSGSPSNTG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP004379_2	2.2\|1327859\|18\|NZ_CP004379\|CRT	1327859-1327876	18	NZ_CP004380.1	1965540-1965557	1	0.944

1. spacer 2.2|1327859|18|NZ_CP004379|CRT matches to position: 1965540-1965557, mismatch: 1, identity: 0.944

cggccgggacatggagcg	CRISPR spacer
cggccgggacattgagcg	Protospacer
************ *****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP004379_2	2.1\|1327814\|27\|NZ_CP004379\|CRT	1327814-1327840	27	KT809302	Haloarcula californiae icosahedral virus 1, complete genome	11055-11081	4	0.852
NZ_CP004379_2	2.1\|1327814\|27\|NZ_CP004379\|CRT	1327814-1327840	27	NZ_CP053345	Herbiconiux sp. SALV-R1 plasmid unnamed1, complete sequence	7093-7119	4	0.852
NZ_CP004379_2	2.1\|1327814\|27\|NZ_CP004379\|CRT	1327814-1327840	27	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	620149-620175	5	0.815
NZ_CP004379_2	2.1\|1327814\|27\|NZ_CP004379\|CRT	1327814-1327840	27	NC_023549	Clavibacter phage CN1A, complete genome	23970-23996	5	0.815
NZ_CP004379_2	2.1\|1327814\|27\|NZ_CP004379\|CRT	1327814-1327840	27	NZ_CP041158	Leisingera aquaemixtae strain R2C4 plasmid unnamed4, complete sequence	2440-2466	5	0.815
NZ_CP004379_2	2.1\|1327814\|27\|NZ_CP004379\|CRT	1327814-1327840	27	NZ_CP027794	Rhodococcus hoagii strain DSSKP-R-001 plasmid plas1, complete sequence	76893-76919	6	0.778
NZ_CP004379_2	2.1\|1327814\|27\|NZ_CP004379\|CRT	1327814-1327840	27	NZ_CP014769	Hymenobacter sp. PAMC 26554 plasmid unnamed1, complete sequence	146043-146069	6	0.778
NZ_CP004379_2	2.1\|1327814\|27\|NZ_CP004379\|CRT	1327814-1327840	27	KX066068	Pseudomonas phage VSW-3, complete genome	19654-19680	6	0.778
NZ_CP004379_2	2.3\|1327895\|36\|NZ_CP004379\|CRT	1327895-1327930	36	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	201580-201615	9	0.75
NZ_CP004379_2	2.3\|1327895\|36\|NZ_CP004379\|CRT	1327895-1327930	36	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	384570-384605	10	0.722

1. spacer 2.1|1327814|27|NZ_CP004379|CRT matches to KT809302 (Haloarcula californiae icosahedral virus 1, complete genome) position: , mismatch: 4, identity: 0.852

cggtgacgacggcggctacggtggtgg	CRISPR spacer
cggtgacgacggcggcgacggtgacga	Protospacer
**************** ******..*.

2. spacer 2.1|1327814|27|NZ_CP004379|CRT matches to NZ_CP053345 (Herbiconiux sp. SALV-R1 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

cggtgacgacggcggctacggtggtgg	CRISPR spacer
tgatgatgacggcggctacggtggggg	Protospacer
.*.***.***************** **

3. spacer 2.1|1327814|27|NZ_CP004379|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 5, identity: 0.815

cggtgacgacggcggctacggtggtgg	CRISPR spacer
cggtggcgacggcggcgacggtggctt	Protospacer
*****.********** *******.

4. spacer 2.1|1327814|27|NZ_CP004379|CRT matches to NC_023549 (Clavibacter phage CN1A, complete genome) position: , mismatch: 5, identity: 0.815

cggtgacgacggcggctacggtggtgg	CRISPR spacer
ctacggggacggcggctacggtggtgg	Protospacer
* ..*. ********************

5. spacer 2.1|1327814|27|NZ_CP004379|CRT matches to NZ_CP041158 (Leisingera aquaemixtae strain R2C4 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

cggtgacgacggcggctacggtggtgg	CRISPR spacer
caaagccgacggcggcgacggtggtgg	Protospacer
*.. * ********** **********

6. spacer 2.1|1327814|27|NZ_CP004379|CRT matches to NZ_CP027794 (Rhodococcus hoagii strain DSSKP-R-001 plasmid plas1, complete sequence) position: , mismatch: 6, identity: 0.778

cggtgacgacggcggctacggtggtgg	CRISPR spacer
cggtgacgacggcggcgacggcccgcg	Protospacer
**************** ****.    *

7. spacer 2.1|1327814|27|NZ_CP004379|CRT matches to NZ_CP014769 (Hymenobacter sp. PAMC 26554 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

cggtgacgacggcggctacggtggtgg	CRISPR spacer
gggtgccgaaggcggctacggtggcct	Protospacer
 **** *** **************.

8. spacer 2.1|1327814|27|NZ_CP004379|CRT matches to KX066068 (Pseudomonas phage VSW-3, complete genome) position: , mismatch: 6, identity: 0.778

cggtgacgacggcggctacggtggtgg	CRISPR spacer
ctgtgacgacggcggcaacggtgactt	Protospacer
* ************** ******..

9. spacer 2.3|1327895|36|NZ_CP004379|CRT matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 9, identity: 0.75

tgcgtcgggtggcggcggcgcgggtgcgcgcagcgg	CRISPR spacer
gggcgcgggtggcggtggcgcgggcgcgcgcgtcgc	Protospacer
 *   **********.********.******. **

10. spacer 2.3|1327895|36|NZ_CP004379|CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 10, identity: 0.722

tgcgtcgggtggcggcggcgcgggtgcgcgcagcgg	CRISPR spacer
cgaaccccatggcggcggcgagggtgcgcgcatcga	Protospacer
.* ..*  .*********** *********** **.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

16045 : 25289

unidentified_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004522151.1\|16045_17593_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2
WP_004194373.1\|17629_18157_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004532195.1\|18153_18837_+	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.0e-05	26.0
WP_004194137.1\|18901_19717_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004538732.1\|19900_21907_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	8.2e-52	34.5
WP_004522147.1\|21940_23071_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.7e-22	27.6
WP_004194034.1\|23336_25289_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2

DBSCAN-SWA_2

308318 : 408607

107

Burkholderia_phage(80.7%)

tail,portal,tRNA,protease,holin,head,capsid,plate,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004521984.1\|308318_309617_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_004527811.1\|309683_310766_+	peptide chain release factor 1	A0A0S4KWG0	Pseudomonas_phage	6.7e-08	46.6
WP_004534980.1\|310809_311667_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_004186955.1\|311746_312055_+	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_004521981.1\|312069_312666_+	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_004521980.1\|312949_313738_+	dioxygenase	NA	NA	NA	NA
WP_004527813.1\|314089_315691_-	APC family permease	NA	NA	NA	NA
WP_004196837.1\|316124_316328_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.3e-21	73.1
WP_004198058.1\|316514_317777_-	Hsp70 family protein	NA	NA	NA	NA
WP_004198059.1\|318439_319045_-	nitroreductase family protein	NA	NA	NA	NA
WP_004198060.1\|319006_319582_+	hypothetical protein	NA	NA	NA	NA
WP_004198061.1\|319541_320825_-	MFS transporter	NA	NA	NA	NA
WP_004553840.1\|320983_321628_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004527819.1\|321965_322589_+	DUF1415 domain-containing protein	NA	NA	NA	NA
WP_004535010.1\|322680_323583_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004535007.1\|323710_324847_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004539229.1\|324823_325129_+	hypothetical protein	NA	NA	NA	NA
WP_004553841.1\|325203_326322_-	acyltransferase	NA	NA	NA	NA
WP_076811889.1\|326320_326800_+	hypothetical protein	NA	NA	NA	NA
WP_004199982.1\|326759_327263_-	lipoprotein	NA	NA	NA	NA
WP_004553842.1\|327866_330032_+	peptidase M1	A0A0P0IY26	Acinetobacter_phage	1.9e-46	27.1
WP_076873039.1\|330613_331012_+	hypothetical protein	NA	NA	NA	NA
WP_004185238.1\|331087_331324_+	hypothetical protein	NA	NA	NA	NA
WP_004204906.1\|331426_331657_+	hypothetical protein	NA	NA	NA	NA
WP_004521964.1\|331890_332247_-	hypothetical protein	NA	NA	NA	NA
WP_004199991.1\|332272_333541_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004521963.1\|333555_335817_+	peptidase domain-containing ABC transporter	A0A2R8FG22	Brazilian_cedratvirus	2.3e-10	31.9
WP_004199995.1\|335813_337262_+	TolC family protein	NA	NA	NA	NA
WP_004521960.1\|337471_338440_-	hypothetical protein	NA	NA	NA	NA
WP_004199998.1\|338565_339417_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_004200000.1\|339567_339681_+	hypothetical protein	NA	NA	NA	NA
WP_004553845.1\|339688_343582_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004200003.1\|343578_344568_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004527834.1\|344572_345505_+	OmpA family protein	NA	NA	NA	NA
WP_004521957.1\|345703_346825_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004549921.1\|346914_349584_-	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.7e-89	32.1
WP_004200010.1\|349617_350718_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004527836.1\|350681_352520_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004204912.1\|352599_353082_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004527837.1\|353139_353643_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004521953.1\|353715_355206_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004521952.1\|355222_355741_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004531875.1\|355777_356449_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004521950.1\|356823_357438_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004521949.1\|357546_358893_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004521948.1\|358889_359675_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004553848.1\|359776_360142_+	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	3.3e-52	87.6
WP_111963042.1\|360245_360836_-	hypothetical protein	NA	NA	NA	NA
WP_076880366.1\|361231_361834_-	site-specific DNA-methyltransferase	K4NZW3	Burkholderia_phage	5.6e-81	87.9
WP_004527843.1\|361731_362145_-\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	8.0e-71	100.0
WP_004552669.1\|362137_362464_-	hypothetical protein	A4JWY2	Burkholderia_virus	2.3e-52	99.1
WP_031313497.1\|363235_363853_-	DUF4276 family protein	NA	NA	NA	NA
WP_004552667.1\|363855_365112_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	3.6e-21	26.2
WP_006027262.1\|365779_366076_+	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	5.6e-50	99.0
WP_004202809.1\|366078_366435_+	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_004531045.1\|366478_367534_-\|portal	phage portal protein	K4NZV0	Burkholderia_phage	4.0e-207	100.0
WP_004531046.1\|367530_369300_-\|terminase	terminase ATPase subunit family protein	K4NXI4	Burkholderia_phage	0.0e+00	100.0
WP_004552664.1\|369443_370253_+\|capsid	GPO family capsid scaffolding protein	K4PAW2	Burkholderia_phage	4.2e-148	100.0
WP_004531048.1\|370286_371300_+\|capsid	phage major capsid protein, P2 family	K4NZP8	Burkholderia_phage	7.2e-190	100.0
WP_004531049.1\|371296_371986_+\|terminase	terminase endonuclease subunit	K4NX86	Burkholderia_phage	2.5e-117	100.0
WP_004531050.1\|372085_372565_+\|head	head completion/stabilization protein	K4NZV5	Burkholderia_phage	5.8e-81	100.0
WP_004524437.1\|372564_372816_+	hypothetical protein	K4NXI9	Burkholderia_phage	7.6e-40	100.0
WP_004524438.1\|372812_373019_+\|tail	tail protein	K4PAW7	Burkholderia_phage	2.4e-31	100.0
WP_004524439.1\|373033_373378_+	membrane protein	K4NZQ3	Burkholderia_phage	2.9e-50	100.0
WP_004524440.1\|373379_373652_+\|holin	phage holin family protein	K4NX91	Burkholderia_phage	8.8e-42	100.0
WP_004531051.1\|373648_374461_+	DUF3380 domain-containing protein	K4NZW0	Burkholderia_phage	1.2e-150	100.0
WP_038741668.1\|374457_374898_+	protein lysB	K4NXJ2	Burkholderia_phage	7.2e-70	99.3
WP_004531054.1\|375002_375419_+\|tail	phage tail protein	A4JWT7	Burkholderia_virus	3.3e-72	100.0
WP_004531055.1\|375415_375883_+	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	1.2e-78	100.0
WP_009897040.1\|376009_376540_+	hypothetical protein	K4NX96	Burkholderia_phage	3.0e-94	100.0
WP_004531056.1\|376705_377482_-	site-specific DNA-methyltransferase	K4NZW3	Burkholderia_phage	1.6e-149	100.0
WP_004531057.1\|377655_378336_+\|plate	phage baseplate assembly protein V	K4NXJ5	Burkholderia_phage	3.0e-123	100.0
WP_004531058.1\|378332_378695_+\|plate	bacteriophage baseplate assembly protein W	K4PAX6	Burkholderia_phage	1.7e-61	100.0
WP_014696810.1\|378691_379597_+\|plate	baseplate assembly protein	K4NZR5	Burkholderia_phage	8.8e-163	99.7
WP_004531060.1\|379589_380144_+\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	2.2e-100	100.0
WP_038803061.1\|380154_382518_+	phage Tail collar domain protein	K4NZW8	Burkholderia_phage	0.0e+00	100.0
WP_004531062.1\|382534_383206_+\|tail	phage tail fiber assembly protein	K4NXJ9	Burkholderia_phage	3.0e-115	100.0
WP_014696808.1\|383261_384434_+\|tail	phage tail sheath protein	K4PAY0	Burkholderia_phage	1.5e-223	100.0
WP_004524455.1\|384449_384959_+\|tail	phage major tail tube protein	K4NZR9	Burkholderia_phage	4.9e-94	100.0
WP_004531064.1\|385016_385361_+\|tail	phage tail assembly protein	K4NXA3	Burkholderia_phage	1.0e-55	100.0
WP_004552648.1\|385369_385483_+\|tail	GpE family phage tail protein	A0A089FGX3	Burkholderia_phage	5.4e-14	100.0
WP_004555835.1\|385485_388446_+	hypothetical protein	K4NZX3	Burkholderia_phage	0.0e+00	100.0
WP_009976644.1\|388463_388889_+\|tail	phage tail protein	K4NXK5	Burkholderia_phage	1.5e-72	99.3
WP_004552642.1\|388888_389989_+	phage late control D family protein	K4PAY4	Burkholderia_phage	3.6e-203	100.0
WP_004549903.1\|390002_390434_-	hypothetical protein	A0A089FKT7	Burkholderia_phage	8.6e-76	100.0
WP_004549902.1\|390868_391591_-	hypothetical protein	K4NZS4	Burkholderia_phage	1.1e-126	100.0
WP_004549901.1\|391643_392102_-	helix-turn-helix transcriptional regulator	K4NXA8	Burkholderia_phage	5.2e-79	100.0
WP_004531068.1\|392185_392422_+	hypothetical protein	K4NZX7	Burkholderia_phage	2.4e-35	100.0
WP_004549900.1\|392425_392722_+	phage DNA-binding protein	E5E3P2	Burkholderia_phage	5.4e-37	84.3
WP_004549899.1\|392709_392958_+	ogr/Delta-like zinc finger family protein	K4PAZ0	Burkholderia_phage	3.0e-41	100.0
WP_004524465.1\|393043_393589_+	Bro-N domain-containing protein	K4NZS9	Burkholderia_phage	7.8e-98	100.0
WP_004549898.1\|393604_393823_+	hypothetical protein	K4NXB1	Burkholderia_phage	1.1e-34	100.0
WP_004524466.1\|393828_394026_+	hypothetical protein	K4NZY3	Burkholderia_phage	1.6e-29	100.0
WP_045586665.1\|394069_394264_+	hypothetical protein	K4NXL1	Burkholderia_phage	4.8e-26	98.4
WP_004531069.1\|394267_394507_+	hypothetical protein	K4PAZ5	Burkholderia_phage	1.4e-35	100.0
WP_004524469.1\|394675_394882_+	hypothetical protein	K4NZT3	Burkholderia_phage	2.7e-35	100.0
WP_004531070.1\|394884_395244_+	hypothetical protein	K4NXB4	Burkholderia_phage	1.1e-60	100.0
WP_004524471.1\|395240_395495_+	hypothetical protein	K4NZY7	Burkholderia_phage	4.5e-40	100.0
WP_014696807.1\|395506_398299_+	hypothetical protein	K4NXL6	Burkholderia_phage	0.0e+00	100.0
WP_076836148.1\|398999_399341_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004189647.1\|400368_401052_-	response regulator	NA	NA	NA	NA
WP_004523096.1\|401052_403461_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004553747.1\|403462_404053_-	DUF4390 domain-containing protein	NA	NA	NA	NA
WP_004523097.1\|404049_405459_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_004189409.1\|405900_406758_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_004525854.1\|406867_407503_-	LysE family translocator	NA	NA	NA	NA
WP_004553746.1\|407623_408607_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0

DBSCAN-SWA_3

632237 : 677230

Burkholderia_phage(58.49%)

transposase,tail,portal,holin,integrase,head,capsid,plate,lysis,terminase

attL 625917:625934|attR 680009:680026

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
625917:625934	attL	NA	NA	NA	NA
WP_038742464.1\|632237_633347_-\|integrase	site-specific integrase	A0A1S5NNJ1	Burkholderia_phage	1.5e-167	79.6
WP_004556612.1\|633214_633550_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014696839.1\|634236_637029_-	hypothetical protein	K4NXL6	Burkholderia_phage	0.0e+00	99.6
WP_004524471.1\|637040_637295_-	hypothetical protein	K4NZY7	Burkholderia_phage	4.5e-40	100.0
WP_004531070.1\|637291_637651_-	hypothetical protein	K4NXB4	Burkholderia_phage	1.1e-60	100.0
WP_004524469.1\|637653_637860_-	hypothetical protein	K4NZT3	Burkholderia_phage	2.7e-35	100.0
WP_004531069.1\|638028_638268_-	hypothetical protein	K4PAZ5	Burkholderia_phage	1.4e-35	100.0
WP_004524467.1\|638271_638466_-	hypothetical protein	K4NXL1	Burkholderia_phage	1.6e-26	100.0
WP_004524466.1\|638509_638707_-	hypothetical protein	K4NZY3	Burkholderia_phage	1.6e-29	100.0
WP_004551086.1\|638712_638931_-	hypothetical protein	A4JWR5	Burkholderia_virus	8.3e-35	100.0
WP_004551085.1\|639015_639264_-	ogr/Delta-like zinc finger family protein	A4JWR6	Burkholderia_virus	6.8e-41	100.0
WP_004534427.1\|639251_639548_-	hypothetical protein	E5E3P2	Burkholderia_phage	8.4e-38	86.5
WP_004534406.1\|639551_639788_-	hypothetical protein	A4JWR7	Burkholderia_virus	3.1e-35	100.0
WP_004534376.1\|639870_640302_+	helix-turn-helix domain-containing protein	A4JWR8	Burkholderia_virus	9.9e-72	100.0
WP_004551084.1\|640351_641095_+	hypothetical protein	A4JWR9	Burkholderia_virus	1.8e-100	100.0
WP_004551083.1\|641134_642034_+	hypothetical protein	A4JWS0	Burkholderia_virus	2.1e-164	99.3
WP_004553037.1\|642041_643139_-	phage late control D family protein	A4JWX2	Burkholderia_virus	8.9e-202	99.5
WP_009914999.1\|643138_643564_-\|tail	phage tail protein	A4JWS2	Burkholderia_virus	3.3e-72	100.0
WP_009971807.1\|643581_646542_-	membrane protein	A4JWS3	Burkholderia_virus	0.0e+00	99.4
WP_004552648.1\|646544_646658_-\|tail	GpE family phage tail protein	A0A089FGX3	Burkholderia_phage	5.4e-14	100.0
WP_004531064.1\|646666_647011_-\|tail	phage tail assembly protein	K4NXA3	Burkholderia_phage	1.0e-55	100.0
WP_014696837.1\|647069_647579_-\|tail	phage major tail tube protein	K4NZR9	Burkholderia_phage	3.2e-93	98.8
WP_014696836.1\|647594_648767_-\|tail	phage tail sheath protein	A4JWS7	Burkholderia_virus	3.7e-222	99.5
WP_004552361.1\|648822_649494_-\|tail	tail assembly chaperone	A4JWS8	Burkholderia_virus	8.6e-115	98.7
WP_038803061.1\|649510_651874_-	phage Tail collar domain protein	K4NZW8	Burkholderia_phage	0.0e+00	100.0
WP_004531060.1\|651884_652439_-\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	2.2e-100	100.0
WP_014696810.1\|652431_653337_-\|plate	baseplate assembly protein	K4NZR5	Burkholderia_phage	8.8e-163	99.7
WP_004531058.1\|653333_653696_-\|plate	bacteriophage baseplate assembly protein W	K4PAX6	Burkholderia_phage	1.7e-61	100.0
WP_004531057.1\|653692_654373_-\|plate	phage baseplate assembly protein V	K4NXJ5	Burkholderia_phage	3.0e-123	100.0
WP_038742039.1\|654544_655303_+	site-specific DNA-methyltransferase	K4NZW3	Burkholderia_phage	1.5e-136	95.1
WP_004553024.1\|655702_656170_-	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	2.8e-72	92.3
WP_004553023.1\|656166_656583_-\|tail	phage tail protein	A4JWT7	Burkholderia_virus	1.3e-68	94.9
WP_045586530.1\|656687_657128_-\|lysis	LysB family phage lysis regulatory protein	K4NXJ2	Burkholderia_phage	1.1e-65	93.2
WP_004553022.1\|657124_657937_-	DUF3380 domain-containing protein	A4JWZ0	Burkholderia_virus	6.5e-149	98.9
WP_004524440.1\|657933_658206_-\|holin	phage holin family protein	K4NX91	Burkholderia_phage	8.8e-42	100.0
WP_004553021.1\|658207_658552_-	membrane protein	K4NZQ3	Burkholderia_phage	6.5e-50	99.1
WP_004553020.1\|658566_658773_-\|tail	tail protein	K4PAW7	Burkholderia_phage	1.7e-29	95.6
WP_004551072.1\|658769_659021_-	hypothetical protein	K4NXI9	Burkholderia_phage	9.2e-38	95.2
WP_004553019.1\|659020_659500_-\|head	head completion/stabilization protein	K4NZV5	Burkholderia_phage	9.3e-79	96.2
WP_014696834.1\|659599_660289_-\|terminase	terminase endonuclease subunit	K4NX86	Burkholderia_phage	2.6e-114	96.9
WP_014696833.1\|660285_661299_-\|capsid	phage major capsid protein, P2 family	K4NZP8	Burkholderia_phage	6.3e-186	97.0
WP_004553016.1\|661332_662142_-\|capsid	GPO family capsid scaffolding protein	K4PAW2	Burkholderia_phage	5.3e-135	90.7
WP_014696832.1\|662285_664055_+\|terminase	terminase ATPase subunit family protein	K4NXI4	Burkholderia_phage	0.0e+00	98.8
WP_004553015.1\|664051_665107_+\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	4.9e-205	98.9
WP_158331355.1\|665581_666142_+	DNA-directed RNA polymerase subunit beta	NA	NA	NA	NA
WP_038742020.1\|666511_667210_-	hypothetical protein	NA	NA	NA	NA
WP_038742018.1\|667212_668097_-	DNA-processing protein DprA	S6BFL3	Thermus_phage	1.1e-35	43.5
WP_014696831.1\|668336_668807_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085952178.1\|668854_669966_-\|transposase	IS3-like element ISBp1 family transposase	NA	NA	NA	NA
WP_076804979.1\|670142_670322_-	hypothetical protein	NA	NA	NA	NA
WP_004553012.1\|670493_671081_+\|integrase	site-specific integrase	A0A0S2SYQ7	Pseudomonas_phage	9.1e-44	50.0
WP_009932253.1\|671132_671453_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	1.0e-12	58.6
WP_009922658.1\|671460_671778_+	helix-turn-helix transcriptional regulator	A0A088CD40	Shigella_phage	6.2e-15	57.0
WP_004530410.1\|671777_672695_+	DUF4935 domain-containing protein	A4PE40	Ralstonia_virus	4.0e-46	40.6
WP_009932250.1\|672948_673491_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	8.1e-47	55.8
WP_009932249.1\|673748_674201_+	VRR-NUC domain-containing protein	Q8W6S1	Burkholderia_virus	2.3e-31	58.8
WP_004530408.1\|674200_675280_+	DUF3396 domain-containing protein	A9YX32	Burkholderia_phage	2.2e-160	99.0
WP_004525721.1\|675436_675685_+	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	4.0e-41	97.6
WP_004195754.1\|676585_677230_+	chitin-binding protein	A0A0K1Y848	Apis_mellifera_filamentous_virus	5.7e-07	30.4
680009:680026	attR	NA	NA	NA	NA

DBSCAN-SWA_4

899908 : 908347

Burkholderia_phage(50.0%)

protease,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004554066.1\|899908_900430_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0
WP_004554067.1\|901143_902199_+\|portal	phage portal protein	A4JWV0	Burkholderia_virus	7.5e-206	99.4
WP_004524431.1\|902305_902578_+	BrnT family toxin	K4NX81	Burkholderia_phage	1.0e-45	100.0
WP_004524430.1\|902537_902810_+	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	6.3e-48	100.0
WP_004554069.1\|903421_903778_-	hypothetical protein	A0A089GLD7	Burkholderia_phage	1.3e-37	100.0
WP_004531044.1\|904060_904762_-	hypothetical protein	A0A089FKS8	Burkholderia_phage	1.0e-134	100.0
WP_004554070.1\|905007_905481_-	DUF4065 domain-containing protein	K4NZT7	Burkholderia_phage	2.8e-88	100.0
WP_004190026.1\|906414_907149_+	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_004189241.1\|907242_907875_+	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004189793.1\|907894_908347_+	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8

DBSCAN-SWA_5

1685507 : 1696459

Streptococcus_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004197486.1\|1685507_1687622_-	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7
WP_004185496.1\|1687922_1688432_-	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_071810810.1\|1688623_1688842_-	hypothetical protein	NA	NA	NA	NA
WP_004189780.1\|1689104_1689683_-	pseudouridine synthase	NA	NA	NA	NA
WP_004189552.1\|1689950_1691210_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_009929279.1\|1691182_1691365_-	hypothetical protein	NA	NA	NA	NA
WP_004552979.1\|1691377_1692982_+	multicopper oxidase family protein	NA	NA	NA	NA
WP_004196460.1\|1693111_1693315_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|1693847_1694162_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196461.1\|1694158_1696459_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1

DBSCAN-SWA_6

2237230 : 2302631

Burkholderia_virus(95.95%)

tail,portal,protease,holin,integrase,head,capsid,terminase

attL 2281700:2281721|attR 2313256:2313277

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004526624.1\|2237230_2238331_-\|integrase	tyrosine-type recombinase/integrase	Q6JIJ8	Burkholderia_virus	5.4e-215	100.0
WP_004526625.1\|2238330_2238555_-	DUF4224 domain-containing protein	Q6JIJ7	Burkholderia_virus	2.9e-35	100.0
WP_004526626.1\|2238600_2238825_+	hypothetical protein	Q6JIJ6	Burkholderia_virus	1.8e-37	100.0
WP_004552963.1\|2238906_2239116_+	hypothetical protein	Q6JIJ5	Burkholderia_virus	1.8e-34	100.0
WP_004526628.1\|2239124_2239370_+	hypothetical protein	Q6JIJ4	Burkholderia_virus	1.5e-37	100.0
WP_004552962.1\|2239442_2240453_-	phage Gp37/Gp68 family protein	Q6JIJ3	Burkholderia_virus	7.7e-200	99.7
WP_004526630.1\|2240410_2240749_-	hypothetical protein	Q6JIJ2	Burkholderia_virus	3.1e-60	100.0
WP_015973597.1\|2240738_2240981_-	hypothetical protein	Q6JIJ1	Burkholderia_virus	1.9e-40	100.0
WP_004526632.1\|2240973_2241231_-	hypothetical protein	Q6JIJ0	Burkholderia_virus	1.7e-42	100.0
WP_004526633.1\|2241227_2243156_-	hypothetical protein	Q6JII8	Burkholderia_virus	9.4e-263	98.8
WP_004526634.1\|2243170_2243449_-	hypothetical protein	Q6JII7	Burkholderia_virus	3.0e-45	100.0
WP_004526635.1\|2243448_2243844_-	hypothetical protein	Q6JII6	Burkholderia_virus	9.4e-69	100.0
WP_004526636.1\|2243846_2244512_-	hypothetical protein	Q6JII5	Burkholderia_virus	2.0e-124	100.0
WP_004526637.1\|2244525_2245233_-	hypothetical protein	Q6JII4	Burkholderia_virus	7.7e-130	100.0
WP_004548444.1\|2245506_2246319_-	prohibitin family protein	Q6JII3	Burkholderia_virus	1.1e-145	100.0
WP_004537646.1\|2246315_2246465_-	bacteriophage protein Gp44	Q8W6Q6	Burkholderia_virus	3.3e-19	100.0
WP_004552960.1\|2246715_2247306_+	hypothetical protein	Q6JII1	Burkholderia_virus	6.4e-106	100.0
WP_004549687.1\|2247480_2247699_-	hypothetical protein	Q6JIH9	Burkholderia_virus	5.7e-36	100.0
WP_009946438.1\|2247746_2248094_-	hypothetical protein	Q6JIH8	Burkholderia_virus	3.8e-58	100.0
WP_004526640.1\|2248578_2248854_-	hypothetical protein	Q6JIH4	Burkholderia_virus	7.2e-44	100.0
WP_004552956.1\|2249355_2250249_+	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	4.3e-170	99.7
WP_004552955.1\|2250403_2251693_+	MFS transporter	Q6JIH2	Burkholderia_virus	1.5e-235	100.0
WP_015973603.1\|2252036_2252438_-	hypothetical protein	Q6JIH0	Burkholderia_virus	1.7e-65	100.0
WP_004552953.1\|2252501_2252816_+	transcriptional regulator	Q6JIG9	Burkholderia_virus	3.0e-54	100.0
WP_015973604.1\|2252932_2253265_+	hypothetical protein	Q6JIG8	Burkholderia_virus	1.4e-57	100.0
WP_004552951.1\|2253261_2253480_-	hypothetical protein	Q6JIG7	Burkholderia_virus	1.1e-31	100.0
WP_009896483.1\|2253694_2254135_+	hypothetical protein	Q6JIG6	Burkholderia_virus	2.9e-79	100.0
WP_004552950.1\|2254363_2255884_+	DNA cytosine methyltransferase	Q6JIG4	Burkholderia_virus	2.0e-252	99.8
WP_004552949.1\|2255885_2256707_+	hypothetical protein	Q6JIG3	Burkholderia_virus	2.8e-147	100.0
WP_004526650.1\|2256703_2256964_+	helix-turn-helix domain-containing protein	Q6JIG2	Burkholderia_virus	4.2e-41	100.0
WP_015973608.1\|2257117_2258110_+	hypothetical protein	Q6JIG0	Burkholderia_virus	5.3e-177	100.0
WP_004552947.1\|2258106_2258658_+	DUF1064 domain-containing protein	Q6JIF9	Burkholderia_virus	1.9e-96	100.0
WP_004549836.1\|2258654_2259029_+	hypothetical protein	Q6JIF8	Burkholderia_virus	8.6e-64	100.0
WP_004526654.1\|2259025_2259451_+	DUF1364 family protein	Q6JIF7	Burkholderia_virus	1.5e-80	100.0
WP_009910613.1\|2259761_2260022_+	hypothetical protein	Q6JIF5	Burkholderia_virus	6.2e-45	100.0
WP_004552943.1\|2260030_2260678_+	hypothetical protein	Q6JIF4	Burkholderia_virus	7.5e-116	100.0
WP_015973610.1\|2260751_2262146_+	ATP-binding protein	Q6JIF3	Burkholderia_virus	1.2e-267	100.0
WP_004552941.1\|2262486_2262873_-	helix-turn-helix transcriptional regulator	Q8W6N2	Burkholderia_virus	1.6e-65	100.0
WP_004549735.1\|2262869_2263127_-	type II toxin-antitoxin system RelE/ParE family toxin	Q8W6N1	Burkholderia_virus	2.4e-41	100.0
WP_004552939.1\|2263185_2263542_+	HNH endonuclease	Q6JIE9	Burkholderia_virus	3.3e-65	100.0
WP_015973592.1\|2263689_2264175_+\|terminase	phage terminase small subunit P27 family	Q6JIN1	Burkholderia_virus	5.9e-89	100.0
WP_004526664.1\|2264184_2265900_+\|terminase	terminase large subunit	Q6JIN0	Burkholderia_virus	0.0e+00	100.0
WP_004552937.1\|2265896_2267210_+\|portal	phage portal protein	Q6JIM9	Burkholderia_virus	1.2e-248	100.0
WP_004526666.1\|2267190_2267877_+\|head,protease	HK97 family phage prohead protease	Q6JIM8	Burkholderia_virus	7.7e-127	100.0
WP_004526667.1\|2267879_2269136_+\|capsid	phage major capsid protein	Q6JIM7	Burkholderia_virus	4.9e-228	100.0
WP_004526668.1\|2269427_2269790_+\|head,tail	phage gp6-like head-tail connector protein	Q6JIM5	Burkholderia_virus	4.4e-57	100.0
WP_015973594.1\|2269791_2270121_+\|head	phage head closure protein	Q6JIM4	Burkholderia_virus	1.2e-56	100.0
WP_004526670.1\|2270113_2270536_+	HK97 gp10 family phage protein	Q6JIM3	Burkholderia_virus	1.5e-69	100.0
WP_004526671.1\|2270532_2270880_+	DUF3168 domain-containing protein	Q6JIM2	Burkholderia_virus	4.5e-59	100.0
WP_004526672.1\|2270941_2271400_+	hypothetical protein	Q6JIM1	Burkholderia_virus	4.9e-61	100.0
WP_004526673.1\|2271427_2271892_+\|tail	tail assembly protein	Q6JIM0	Burkholderia_virus	9.3e-84	100.0
WP_004526674.1\|2271891_2272176_+	DUF4035 domain-containing protein	Q6JIL9	Burkholderia_virus	6.8e-45	100.0
WP_004552935.1\|2272189_2276254_+\|tail	phage tail tape measure protein	Q6JIL8	Burkholderia_virus	0.0e+00	100.0
WP_004548805.1\|2276250_2276589_+\|tail	phage tail protein	Q8W6T5	Burkholderia_virus	8.0e-61	100.0
WP_004552934.1\|2276597_2277986_+\|tail	tail fiber domain-containing protein	Q6JIL6	Burkholderia_virus	5.0e-274	100.0
WP_004526678.1\|2277982_2278666_+\|tail	phage minor tail protein L	Q6JIL5	Burkholderia_virus	1.3e-134	100.0
WP_004526679.1\|2278715_2279468_+	C40 family peptidase	Q6JIL4	Burkholderia_virus	7.1e-150	100.0
WP_004526680.1\|2279464_2280049_+\|tail	tail assembly protein	Q6JIL3	Burkholderia_virus	6.8e-100	99.5
WP_004552932.1\|2280045_2283351_+\|tail	phage tail protein	Q6JIL2	Burkholderia_virus	0.0e+00	100.0
2281700:2281721	attL	NA	NA	NA	NA
WP_004552931.1\|2283395_2283662_+	hypothetical protein	Q8W6S9	Burkholderia_virus	2.5e-49	100.0
WP_004552930.1\|2283661_2284396_+	hypothetical protein	Q8W6S8	Burkholderia_virus	1.2e-146	100.0
WP_004552929.1\|2284438_2284651_+\|holin	class II holin gp23	Q8W6S7	Burkholderia_virus	6.6e-29	100.0
WP_004552928.1\|2284643_2285135_+	lysozyme	Q6JIK8	Burkholderia_virus	7.8e-89	100.0
WP_004552927.1\|2285134_2285680_+	lysozyme	Q8W6S5	Burkholderia_virus	4.3e-88	100.0
WP_004526686.1\|2285822_2286611_+	DNA adenine methylase	Q8W6S4	Burkholderia_virus	6.9e-156	100.0
WP_004526687.1\|2286863_2287598_+	hypothetical protein	Q8W6S3	Burkholderia_virus	1.6e-130	100.0
WP_004552925.1\|2287779_2288340_+	PAAR domain-containing protein	Q8W6S2	Burkholderia_virus	7.5e-104	100.0
WP_004552924.1\|2288336_2289071_+	VRR-NUC domain-containing protein	Q8W6S1	Burkholderia_virus	3.6e-138	100.0
WP_004526688.1\|2289098_2290190_+	DUF3396 domain-containing protein	Q8W6S0	Burkholderia_virus	1.5e-212	100.0
WP_011325405.1\|2290322_2290964_-	hypothetical protein	Q8W6R9	Burkholderia_virus	1.2e-118	100.0
WP_015967370.1\|2291049_2291721_+	DUF159 family protein	Q8W6R8	Burkholderia_virus	6.8e-136	100.0
WP_004536460.1\|2292159_2292618_+	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_004266561.1\|2292769_2293588_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004191764.1\|2294259_2294451_+	lipoprotein	NA	NA	NA	NA
WP_004531119.1\|2294704_2296096_-	MATE family efflux transporter	NA	NA	NA	NA
WP_004531120.1\|2296103_2296421_-	DUF2288 domain-containing protein	NA	NA	NA	NA
WP_004193897.1\|2296685_2298311_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	2.3e-68	35.4
WP_004192280.1\|2298290_2298404_+	hypothetical protein	NA	NA	NA	NA
WP_004531123.1\|2298415_2298589_+	hypothetical protein	NA	NA	NA	NA
WP_004192768.1\|2298666_2299368_-	peptidoglycan DD-metalloendopeptidase family protein	A0A292GJG6	Xanthomonas_phage	9.9e-13	44.8
WP_004526695.1\|2299664_2300573_-	hypothetical protein	NA	NA	NA	NA
WP_004521810.1\|2301120_2301951_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_038741908.1\|2302244_2302631_-\|integrase	tyrosine-type recombinase/integrase	A0A0M4R586	Salmonella_phage	3.9e-19	52.2
2313256:2313277	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2353222 : 2400965

uncultured_Caudovirales_phage(33.33%)

transposase,plate,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004534956.1\|2353222_2355073_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004536269.1\|2355100_2356516_-	hypothetical protein	NA	NA	NA	NA
WP_004550614.1\|2356539_2356806_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_076830677.1\|2357065_2357293_-	hypothetical protein	NA	NA	NA	NA
WP_004552908.1\|2357326_2360125_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	5.2e-28	25.1
WP_004535790.1\|2360127_2360961_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_038741925.1\|2361097_2361655_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_004531151.1\|2361651_2362245_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_004546127.1\|2362241_2364650_+	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_004556888.1\|2364758_2368094_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004556889.1\|2369652_2369895_+	hypothetical protein	NA	NA	NA	NA
WP_004552903.1\|2369912_2370218_+	hypothetical protein	NA	NA	NA	NA
WP_004552902.1\|2370230_2373071_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.4e-20	25.9
WP_004526759.1\|2373072_2373948_+	hypothetical protein	NA	NA	NA	NA
WP_004531157.1\|2373944_2376788_+	hypothetical protein	NA	NA	NA	NA
WP_004531158.1\|2376905_2377826_+	hypothetical protein	NA	NA	NA	NA
WP_004526762.1\|2377956_2378208_+	DUF1153 domain-containing protein	NA	NA	NA	NA
WP_122657026.1\|2378165_2379074_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_004552900.1\|2379703_2379997_+	hypothetical protein	NA	NA	NA	NA
WP_080014833.1\|2380939_2381632_+	hypothetical protein	NA	NA	NA	NA
WP_009951519.1\|2382204_2382372_-	hypothetical protein	A0A0P0ZBS5	Stx2-converting_phage	9.5e-07	50.0
WP_004538387.1\|2383129_2383576_+	hypothetical protein	NA	NA	NA	NA
WP_153260188.1\|2384719_2385145_+	hypothetical protein	NA	NA	NA	NA
WP_038741900.1\|2385803_2386724_+	hypothetical protein	NA	NA	NA	NA
WP_004552896.1\|2386983_2388297_+	divalent metal cation transporter	NA	NA	NA	NA
WP_038728684.1\|2389189_2389459_+	hypothetical protein	NA	NA	NA	NA
WP_004193855.1\|2389721_2390003_-	H-NS histone family protein	NA	NA	NA	NA
WP_004552893.1\|2390470_2391454_-	amidohydrolase family protein	NA	NA	NA	NA
WP_004538381.1\|2391498_2392785_-	MFS transporter	NA	NA	NA	NA
WP_004196705.1\|2393201_2394095_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004531175.1\|2394432_2394654_+	hypothetical protein	NA	NA	NA	NA
WP_004526780.1\|2394739_2394925_+	hypothetical protein	NA	NA	NA	NA
WP_004526781.1\|2394911_2395457_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526782.1\|2395509_2396070_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526783.1\|2396146_2396671_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526784.1\|2396688_2397528_+	molecular chaperone	NA	NA	NA	NA
WP_004534736.1\|2397572_2399984_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004521738.1\|2399999_2400965_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_8

3202765 : 3208455

Ralstonia_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004527234.1\|3202765_3202999_+	hypothetical protein	A4PE26	Ralstonia_virus	4.3e-13	60.6
WP_004531416.1\|3203034_3203262_-	hypothetical protein	Q8W6S4	Burkholderia_virus	3.8e-22	75.8
WP_009937072.1\|3203515_3203911_+	hypothetical protein	NA	NA	NA	NA
WP_144434369.1\|3204121_3205231_+\|transposase	IS3-like element ISBp1 family transposase	NA	NA	NA	NA
WP_004527236.1\|3205402_3205828_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	3.8e-15	49.4
WP_004527237.1\|3205824_3206331_+	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	5.1e-19	40.1
WP_038763587.1\|3206672_3207275_+	hypothetical protein	NA	NA	NA	NA
WP_009920998.1\|3207281_3208007_+	hypothetical protein	A4PE26	Ralstonia_virus	5.8e-32	44.0
WP_076811937.1\|3208191_3208455_-	hypothetical protein	Q8W6S4	Burkholderia_virus	5.0e-26	85.5

DBSCAN-SWA_9

3406936 : 3475449

uncultured_Caudovirales_phage(26.32%)

tail,portal,tRNA,protease,integrase,head,capsid,plate,terminase

attL 3448328:3448345|attR 3464495:3464512

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004527342.1\|3406936_3408415_-\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_004193249.1\|3408458_3409430_-	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_004205123.1\|3409533_3410472_-	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004192752.1\|3410519_3411917_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	1.8e-42	33.8
WP_004195907.1\|3412148_3412871_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004191635.1\|3412927_3413503_+	peptidyl-prolyl cis-trans isomerase	A0A1V0SCU1	Indivirus	5.3e-12	39.3
WP_004193779.1\|3413583_3414075_+	peptidyl-prolyl cis-trans isomerase	A0A1V0SCU1	Indivirus	4.2e-10	33.3
WP_004550230.1\|3414099_3414900_+	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_004552789.1\|3415235_3416021_-	serine O-acetyltransferase	NA	NA	NA	NA
WP_004552788.1\|3416211_3417123_-	RNA methyltransferase	NA	NA	NA	NA
WP_004532151.1\|3417128_3417380_-	hypothetical protein	NA	NA	NA	NA
WP_004191664.1\|3417423_3418227_+	inositol monophosphatase	NA	NA	NA	NA
WP_004527347.1\|3418506_3418779_-	hypothetical protein	NA	NA	NA	NA
WP_004191077.1\|3418962_3419142_-	hypothetical protein	NA	NA	NA	NA
WP_004192883.1\|3419686_3419914_-	hypothetical protein	NA	NA	NA	NA
WP_004552787.1\|3420677_3421079_-	hypothetical protein	NA	NA	NA	NA
WP_004552786.1\|3421954_3422278_-	hypothetical protein	NA	NA	NA	NA
WP_004552785.1\|3422299_3422767_-	hypothetical protein	NA	NA	NA	NA
WP_004552784.1\|3423414_3424029_-	hypothetical protein	NA	NA	NA	NA
WP_009929444.1\|3424329_3425010_-	DUF159 family protein	Q8W6R8	Burkholderia_virus	9.1e-104	79.5
WP_009929443.1\|3425091_3425556_+	hypothetical protein	C7BGE3	Burkholderia_phage	7.4e-49	60.4
WP_004552781.1\|3425555_3425837_+	hypothetical protein	NA	NA	NA	NA
WP_004552780.1\|3425898_3426324_+	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	4.9e-15	48.3
WP_004552779.1\|3426320_3426827_+	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	8.7e-19	39.4
WP_004552778.1\|3426819_3427293_+	hypothetical protein	NA	NA	NA	NA
WP_004552777.1\|3427249_3427768_+	hypothetical protein	NA	NA	NA	NA
WP_004552776.1\|3427764_3428508_+	hypothetical protein	A4PE26	Ralstonia_virus	8.0e-37	42.9
WP_004552775.1\|3428543_3429332_-	DNA adenine methylase	Q8W6S4	Burkholderia_virus	4.4e-150	96.2
WP_004552774.1\|3429474_3429999_-	lysozyme	Q8W6S5	Burkholderia_virus	6.0e-79	93.4
WP_004552773.1\|3429998_3430496_-	lysozyme	A4JX20	Burkholderia_virus	2.9e-67	78.8
WP_004533694.1\|3430488_3430683_-	hypothetical protein	NA	NA	NA	NA
WP_004552772.1\|3430758_3431811_-	phage late control protein	A0A2H4JBF6	uncultured_Caudovirales_phage	2.7e-78	44.2
WP_004540041.1\|3431820_3432027_-\|tail	phage tail protein	A0A2H4J9Z9	uncultured_Caudovirales_phage	4.0e-15	61.2
WP_004552771.1\|3432001_3432883_-\|tail	phage tail protein	A0A2H4J875	uncultured_Caudovirales_phage	8.6e-30	37.0
WP_004552770.1\|3432891_3435306_-\|tail	phage tail tape measure protein	A0A2H4JG00	uncultured_Caudovirales_phage	9.5e-71	34.2
WP_004552769.1\|3435393_3435696_-\|tail	phage tail assembly protein	V5YST8	Pseudomonas_phage	1.5e-05	37.2
WP_004552768.1\|3435765_3436269_-\|tail	phage major tail tube protein	Q7M2A5	Pseudomonas_phage	4.3e-42	50.6
WP_004552767.1\|3436279_3437449_-\|tail	phage tail sheath family protein	A0A2H4J869	uncultured_Caudovirales_phage	3.4e-159	72.7
WP_004552766.1\|3437514_3437967_-\|tail	tail assembly chaperone	A4JWL9	Burkholderia_virus	2.7e-43	75.0
WP_004552413.1\|3437982_3439446_-	hypothetical protein	A4JWL8	Burkholderia_virus	1.6e-214	78.2
WP_004539949.1\|3439433_3440009_-\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	6.0e-32	47.7
WP_004533630.1\|3440001_3440895_-\|plate	baseplate J protein	D5LGZ3	Escherichia_phage	1.9e-48	40.7
WP_004552765.1\|3440891_3441236_-	hypothetical protein	A0A2H4JA09	uncultured_Caudovirales_phage	1.4e-23	50.9
WP_004552764.1\|3441232_3441439_-	hypothetical protein	NA	NA	NA	NA
WP_004552763.1\|3441503_3442184_-\|plate	phage baseplate assembly protein V	A0A1B2LRU5	Wolbachia_phage	2.4e-19	35.1
WP_009935706.1\|3442186_3442720_-	hypothetical protein	Q9JML9	Wolbachia_phage	3.6e-23	39.5
WP_004539763.1\|3442709_3443240_-\|tail	phage tail protein	A0A2H4JBV1	uncultured_Caudovirales_phage	9.2e-11	28.0
WP_004552761.1\|3443241_3443532_-	hypothetical protein	NA	NA	NA	NA
WP_004550216.1\|3443535_3444561_-\|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	1.7e-109	59.1
WP_004552760.1\|3444595_3444940_-\|head	head decoration protein	NA	NA	NA	NA
WP_004552759.1\|3444966_3446067_-\|protease	Clp protease ClpP	A0A2H4JDI2	uncultured_Caudovirales_phage	1.1e-47	36.1
WP_004552758.1\|3446063_3447557_-\|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	7.5e-135	51.2
WP_004552757.1\|3447553_3447760_-	hypothetical protein	NA	NA	NA	NA
WP_004552756.1\|3447770_3449756_-\|terminase	phage terminase large subunit family protein	A0A2D1GMT1	Marinobacter_phage	2.1e-180	53.4
3448328:3448345	attL	NA	NA	NA	NA
WP_004552755.1\|3449718_3450288_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_009935698.1\|3450652_3451027_-	hypothetical protein	NA	NA	NA	NA
WP_004533678.1\|3451374_3451962_-	hypothetical protein	NA	NA	NA	NA
WP_004552754.1\|3452179_3454672_-	virulence protein E	A0A2D1GN57	Marinobacter_phage	4.7e-97	41.8
WP_004552753.1\|3454791_3455262_-	hypothetical protein	NA	NA	NA	NA
WP_004552751.1\|3455568_3455922_-	hypothetical protein	NA	NA	NA	NA
WP_038741767.1\|3455935_3456463_-	hypothetical protein	C7BGG0	Burkholderia_phage	7.4e-29	46.5
WP_045586622.1\|3456551_3456821_-	hypothetical protein	NA	NA	NA	NA
WP_009909040.1\|3456929_3457415_+	helix-turn-helix transcriptional regulator	A0A193GYL7	Enterobacter_phage	4.4e-12	41.2
WP_128972304.1\|3457362_3457818_+	hypothetical protein	NA	NA	NA	NA
WP_004550209.1\|3457946_3458165_+	hypothetical protein	NA	NA	NA	NA
WP_004552748.1\|3458216_3458552_+	hypothetical protein	NA	NA	NA	NA
WP_004534172.1\|3458548_3459154_+	hypothetical protein	NA	NA	NA	NA
WP_004552747.1\|3459150_3459600_+	hypothetical protein	NA	NA	NA	NA
WP_004540046.1\|3459599_3460916_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_004552746.1\|3461029_3461359_+	hypothetical protein	NA	NA	NA	NA
WP_004552745.1\|3461367_3461841_+	hypothetical protein	B5TA88	Burkholderia_phage	3.0e-05	71.4
WP_009890227.1\|3461849_3462092_+	AlpA family phage regulatory protein	C7BGF0	Burkholderia_phage	9.3e-19	59.2
WP_004552744.1\|3462042_3463344_-\|integrase	integrase family protein	C7BGE7	Burkholderia_phage	1.4e-148	58.9
WP_038716247.1\|3463503_3466185_+	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	9.3e-27	24.3
3464495:3464512	attR	NA	NA	NA	NA
WP_038741765.1\|3466171_3467470_+	hypothetical protein	NA	NA	NA	NA
WP_004524740.1\|3467449_3467995_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_028359068.1\|3468063_3469251_+	cupin	NA	NA	NA	NA
WP_004193059.1\|3469977_3470754_-	MBL fold metallo-hydrolase	U5PVD0	Bacillus_phage	3.3e-09	26.6
WP_004524737.1\|3470758_3471901_-	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_004191516.1\|3472011_3472914_-	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_045586624.1\|3472958_3473576_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004191887.1\|3473572_3474775_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_004192745.1\|3474783_3475449_-\|protease	site-2 protease family protein	NA	NA	NA	NA

DBSCAN-SWA_10

3761960 : 3770803

Tanapox_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009955224.1\|3761960_3762803_+	alpha/beta hydrolase	A7XCB7	Tanapox_virus	1.6e-17	27.0
WP_004522362.1\|3763145_3764069_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	2.4e-43	36.2
WP_004552706.1\|3764247_3765543_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004550116.1\|3765769_3766672_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	3.3e-53	39.9
WP_004189725.1\|3767007_3767325_-	competence protein ComE	NA	NA	NA	NA
WP_004552705.1\|3767396_3768389_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	2.6e-27	30.6
WP_009921652.1\|3768447_3769371_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.3e-15	27.1
WP_004537711.1\|3769402_3770803_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	4.2e-79	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP004380

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP004379

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection