CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP006871	Streptomyces albulus ZPM, complete genome	11 crisprs	csa3,WYL,casR,DEDDh,cas4,cas1,DinG,cas3,c2c9_V-U4	2	6	3	0

1. NZ_CP006871

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP006871_1

• CRISPR_ID: NZ_CP006871_1
• CRISPR_location: 3636927-3637033
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP006871_1

Consensus_repeat	Method
TGCTCTGCCAATTGAGCTACAGGGGATTG	CRISPRCasFinder

spacers of NZ_CP006871_1

>1.1|3636956|49|NZ_CP006871|CRISPRCasFinder
AGCTCCCCCGACTGGACTCGAACCAGTAACCTGCCGGTTAACAGCCGGC

CRISPR arrays and Neighbor proteins around NZ_CP006871_1

CRISPR arrays

The CRISPR arrays of NZ_CP006871_1

>merge|NZ_CP006871|1|3636927-3637033|CRISPRCasFinder
TGCTCTGCCAATTGAGCTACAGGGGATTGAGCTCCCCCGACTGGACTCGAACCAGTAACCTGCCGGTTAACAGCCGGCTGCTCTGCCAATTGAGCTACAGGGGATTG

>NZ_CP006871|1|1|3636927-3637033|CRISPRCasFinder
TGCTCTGCCAATTGAGCTACAGGGGATTG	AGCTCCCCCGACTGGACTCGAACCAGTAACCTGCCGGTTAACAGCCGGC
TGCTCTGCCAATTGAGCTACAGGGGATTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_037683299.1|3630917_3631565_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016571863.1|3633782_3634196_-|thioredoxin	unknown	unknown	gnl|CDD|200072
NZ_CP006871.1|WP_063789840.1|3647426_3648410_-|hypothetical-protein	unknown	unknown	gnl|CDD|225049
NZ_CP006871.1|WP_037683297.1|3627392_3628121_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|369777
NZ_CP006871.1|WP_016575987.1|3629798_3630062_+|hypothetical-protein	unknown	unknown	gnl|CDD|225391
NZ_CP006871.1|WP_020930948.1|3630058_3630934_+|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
NZ_CP006871.1|WP_016574528.1|3651871_3652327_-|gamma-glutamylcyclotransferase	unknown	unknown	gnl|CDD|377602
NZ_CP006871.1|WP_020931364.1|3646032_3647400_-|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|235098
NZ_CP006871.1|WP_016571865.1|3635636_3636512_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP006871.1|WP_037637133.1|3650752_3651724_-|adenosine-deaminase	unknown	unknown	gnl|CDD|236480
NZ_CP006871.1|WP_016571864.1|3634672_3635473_+|hypothetical-protein	unknown	unknown	gnl|CDD|293795
NZ_CP006871.1|WP_016571866.1|3637246_3637546_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_020931365.1|3644546_3645809_-|ferredoxin	unknown	unknown	gnl|CDD|170080
NZ_CP006871.1|WP_016571862.1|3633162_3633777_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP006871.1|WP_016576178.1|3642562_3643582_-|threo-3-hydroxy-L-aspartate-ammonia-lyase	unknown	unknown	gnl|CDD|235918
NZ_CP006871.1|WP_037684295.1|3640568_3642485_-|DNA-primase	unknown	unknown	gnl|CDD|235551
NZ_CP006871.1|WP_107080239.1|3626493_3627396_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016575073.1|3648571_3650734_+|molybdopterin-oxidoreductase	unknown	unknown	gnl|CDD|239155
NZ_CP006871.1|WP_016571867.1|3637613_3639068_+|carbohydrate-kinase	unknown	unknown	gnl|CDD|198375
NZ_CP006871.1|WP_016571861.1|3632016_3633048_+|rod-shape-determining-protein	unknown	unknown	gnl|CDD|237564

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_016576178.1|3642562_3643582_-|threo-3-hydroxy-L-aspartate-ammonia-lyase	gnl|CDD|235918	PRK07048, PRK07048, threo-3-hydroxy-L-aspartate ammonia-lyase.	2.679e-158
NZ_CP006871.1|WP_016571863.1|3633782_3634196_-|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	4.11115e-36
NZ_CP006871.1|WP_063789840.1|3647426_3648410_-|hypothetical-protein	gnl|CDD|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	8.27587e-25
NZ_CP006871.1|WP_037683297.1|3627392_3628121_+|methyltransferase-domain-containing-protein	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.35968e-20
NZ_CP006871.1|WP_016575987.1|3629798_3630062_+|hypothetical-protein	gnl|CDD|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	1.0365e-15
NZ_CP006871.1|WP_020930948.1|3630058_3630934_+|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.42151e-21
NZ_CP006871.1|WP_016571865.1|3635636_3636512_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	2.22183e-20
NZ_CP006871.1|WP_037637133.1|3650752_3651724_-|adenosine-deaminase	gnl|CDD|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	6.83897e-155
NZ_CP006871.1|WP_016571864.1|3634672_3635473_+|hypothetical-protein	gnl|CDD|293795	cd07709, flavodiiron_proteins_MBL-fold, catalytic domain of flavodiiron proteins (FDPs) and related proteins; MBL-fold metallo-hydrolase domain. FDPs catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively. In addition to this N-terminal catalytic domain they contain a C-terminal flavin mononucleotide-binding flavodoxin-like domain. Although some FDPs are able to reduce NO or O2 with similar catalytic efficiencies others are selective for either NO or O2, such as Escherichia coli flavorubredoxin which is selective toward NO and G. intestinalis FDP which is selective toward O2. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. Some members of this subgroup are single domain.	1.41504e-36
NZ_CP006871.1|WP_020931364.1|3646032_3647400_-|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NZ_CP006871.1|WP_020931365.1|3644546_3645809_-|ferredoxin	gnl|CDD|170080	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional.	4.9884e-70
NZ_CP006871.1|WP_016571862.1|3633162_3633777_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	2.40638e-57
NZ_CP006871.1|WP_037684295.1|3640568_3642485_-|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP006871.1|WP_016574528.1|3651871_3652327_-|gamma-glutamylcyclotransferase	gnl|CDD|377602	pfam06094, GGACT, Gamma-glutamyl cyclotransferase, AIG2-like. GGACT, gamma-glutamylamine cyclotransferase, is a ubiquitous enzyme found in bacteria, plants, and metazoans from Dictyostelium through to humans. It converts gamma-glutamylamines to free amines and 5-oxoproline.	1.66609e-19
NZ_CP006871.1|WP_016575073.1|3648571_3650734_+|molybdopterin-oxidoreductase	gnl|CDD|239155	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol oxidation via a membrane-anchored tetraheme cytochrome. Members of the MopB_Nitrate-R-NapA CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_CP006871.1|WP_016571867.1|3637613_3639068_+|carbohydrate-kinase	gnl|CDD|198375	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases. This subgroup is composed of D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17) from bacteria and eukaryota. They share high sequence similarity with Escherichia coli xylulokinase (EcXK), which catalyzes the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. Some uncharacterized sequences are also included in this subfamily. EcXK exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ might be required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	4.83422e-113
NZ_CP006871.1|WP_016571861.1|3632016_3633048_+|rod-shape-determining-protein	gnl|CDD|237564	PRK13930, PRK13930, rod shape-determining protein MreB; Provisional.	3.22899e-129

Protein sequences

>NZ_CP006871.1|WP_016571865.1|3635636_3636512_+|glycosyltransferase-family-2-protein
MRQLRVGVAILTMGNRPAELQELLDSVAKQDLPATHIVVVGNGSPLPPLPEGVTGVSLSENLGVSGGRNVALDELRKLGDLDVVVDLDDDGLLISPDVFSRLAELYEQDPKLGIVSFRIADELGRTQRRHVPRLRVGDPQQGGLVTTFLGGGHALSVPMLDRTGGWPDEFFYAHEETDLAWRALDDGWHIRYAPEMVLQHPYTSPTRHAVYHRMVARNRVWLAKRHLPAVLVPVYLGVWAGLTAVRSPSAAGLRAWAAGFAEGVRTPCGRRRPMRWRTVWRMTRLGRPPVI
>NZ_CP006871.1|WP_016571864.1|3634672_3635473_+|hypothetical-protein
MDATDTRVDEIADGIYRISTFVPDVAAPAGFTFNQFLIDAEEPLLFHTGMRHLFPRVSEAVRRVVPLDQLRWLAFGHVEADECGAMNEFLAVAPRAQVAHGLQGCLVSLNDLADRPPRPLAHGETLDLGGKEVLRRRVLHLNTPHVPHNWEARVLFEETTGTLLCGDLFTHLGNGPPVTDHDLVEPALDAEEVFRQTSCLTAAVETLRSLARLSPSTLAVMHGSSYGGDGAAALRALADGYQERFGPEREFAARPSALAGASAPQG
>NZ_CP006871.1|WP_016571863.1|3633782_3634196_-|thioredoxin
MSTVELTKENFDEIVSGNDFVLIDFWAEWCGPCKQFGPVFERSSETHGDLVFAKVNTEKEPELAAAFDIRSIPTLMIVRQNIAVFAQPGALPEAALEDVIGQARALDMDEVRASVAEAQAQQAQQGQQGQAGNGEQA
>NZ_CP006871.1|WP_016571862.1|3633162_3633777_-|histidine-phosphatase-family-protein
MSELLLVRHGETEWSRDGRHTSWTDLPLTTDGEEQARALRPLLSGRKVARVYASPMQRALRTAELAGLPTPHVLDDLREWDYGGDEGITTAEIHRSRPDWYLFDDGVAPGPAEHPGESPEEVGARADRVLALIAPHLTGDEDDQGDEGDVALVGHAHFLRVLTARRLGLPASAGGLFTFGTGAVGVLGTEHDRPAVVAWNARSL
>NZ_CP006871.1|WP_016571861.1|3632016_3633048_+|rod-shape-determining-protein
MTISLAQLRRCSAAVDLGAARTRVYVKNQGLVVDEPTVAAVNTRTGSMLAVGAQAELMDGRTPDYIRVVRPVSNGTVVDIDMAQRLLRHLVGDKLRKTWRRRPTMRAAVCLPYGSEPLAQRAAVETLTGLGARRVELVDTLVAAAVGCGLPVEQPEATMIVVCGAGTTQVAVLSLGSIVAAETVPVGGNAIDHAVIQHLRLHHELMLPNQSVRPLHLMLSGDGELTPGSTEVHGRDVVSGLARSVHVDTERVRRAIITPLTAILDGIGAVLRRCPPDLVADLGERGIMLAGGSALIPGLEPMIHEATSMPVHIADQPGTCAVQGLGAMIEGKVQPLHLDPMAP
>NZ_CP006871.1|WP_037683299.1|3630917_3631565_+|hypothetical-protein
MTPATDNAPPAGSGAPSDLPGPLAFQLVLLRRMADHQPVLVEDALRQLGVTRAQMREANRRWQARMHNPRARAGLQPYRALLGTPEATAARRIGDLTCKALTWPVPLWPDLRFEVLTAPGGSVWNAWLVRAPGAPAPDLRTTADLAPWSCTVDEVARAFAPAHPMEGSAPTRWRLACTAPGPDGPPQDVIAEFTWGLYQRRAEPTSTGPTTTGTP
>NZ_CP006871.1|WP_020930948.1|3630058_3630934_+|FkbM-family-methyltransferase
MTLAARVGPWLPGRLVSALAAGLYPRFEPELGRLHDLCPAGGTAVDVGGWYGPWTRRLARHADRVVTIEPVPHLARVLASVTPAHVDIISAAATDHTGCATLWLPPGGRGDRGVSSLVRRDVHAATLDVPCLPLDALDLTTVTLIKIDVDGGELAVLRGAARTIERERPALFIELETRIQPLAPVLEWTAARGYRGWVLPHDRWLPLSDFDLPAHQSRTSHVAEHGLLRRSLAPHRRYVNSVLFLPDGLHPGPVRTPRTAHTSRTPRTPPAAAPAPPPAGIHDHVHHDPRH
>NZ_CP006871.1|WP_016575987.1|3629798_3630062_+|hypothetical-protein
MKADDALLRILACPIDKGPLALLAAEGALYNPRLRRRYPILDGIPQLLPSSGEQLSDADHERAVRQIEEAAEAEAEARAGQTEGAGS
>NZ_CP006871.1|WP_037683297.1|3627392_3628121_+|methyltransferase-domain-containing-protein
MTALRDFYENPAVPVASGDARTRRQARLLARALGPVRADAPPATVLDIGCGDGTAAATAADVLTGHRVVGVDWSQDALRRAATHLGHVVRGELTDGGLPFTTGSADAVLFSEVIEHLVDPDAALDELRRVLRPGGHLLLSTPNLAAWYNRGLLLAGVQPVFSEVSLRGIHGRPGTHVVGHLRLYTARALRAFLTASGFDVIRIAGAPYHDVPRPLRPLDRAACHTPSLSSILLAHARPRYAP
>NZ_CP006871.1|WP_107080239.1|3626493_3627396_+|hypothetical-protein
MATHPPPYPPGPLTRPARLAPDHTATTPHRSTPRSPRPGNGMLLAALPLPARPHHTHTTGHSPPSPHTVNDQLLVATHLMATHWNALHDRPAAPVIVTMPIDDRPRGPHMPIGNGTRLTPVAFPPTPTRSPFLPQAPTPTVTHLLHHTATRTRALKSATPGPQLGFPSTALTSLPLPVGARRALTRTLRSLAAPWTPTALLSNIGRVPYPLDFGDTGGRATAVWFSAPARMPRGLSITTATTRDGDRIHLALRWSRALLDDAAAARLLALFRTSLATTASATTPPPPVGAAPRTEGGGTP
>NZ_CP006871.1|WP_016571866.1|3637246_3637546_+|hypothetical-protein
MRYRLTFIAGLAVGYVLGTRAGRERYEQLRKSAQRIAQNPAVRNTAESAALTGRQAASKAFVTVSTKVEGRLPAPVAERVRSLREQRAADDDEWGTSNT
>NZ_CP006871.1|WP_016571867.1|3637613_3639068_+|carbohydrate-kinase
MGIVAGLDSSSESTRIVVCDADTGAVIRQGYAPHPVEKGPEVDPQAWLMSLGEAAGNGLLEGVQAIGVAAQQNGLVPLDAEGAPVRPALVGNDKRAQSAAADLVDALGGRMAWAQAVGSVPQAQHPVTKMRWLARAEAANAARIVEVMTPHDWLAWQLLGRPARRTTDRGGASATGYWSAASGAYRSDLVELALGHQVRLPEVLGPSGTAGFTPEGLLISAGTGETMAAAFGLGVGVGDAVVSLGASGSVFAVHEEALADPTGTITSLADATGRHLPVVHTTNAVRVLRGAAEMLGTDLAGLSELALASSPGAYGMVMLPYLEGERTPHLPHTAGSLHGMRRESMKPEHVARAAVEGMLCGLADALDVLRGRGVAVRRVFLLGAAAELGAVQAAAPGLFGAQVVVPQPAEYAALGAARQAAWAWQVAHGTAADGGGGYPEPPQWPAAASQVFEPGEELPVWQAVRQQFTAVRDEVHPGAFQREG
>NZ_CP006871.1|WP_037684295.1|3640568_3642485_-|DNA-primase
MAGRINDDDVKAVRDAVPIDAVVSEYLQLRNAGGGNLKGLCPFHDEKSPSFHVSPAKGLYHCFGCQEGGDTVDFVMKIDHLSFAETIERLAAQAGITLRYEEGGYTPGRQQGERTRLVEAHKAAAQYYTEQLESPEAVIARTFLADRGFDQDAAGHFSVGYSPAGWDHLTRFLRGRGFSDKELILSGLSQEGRRGPIDRFRGRLMWPIRDISGEVVGFGARKLRDDDNGPKYLNTPETPLYRKSQVLYGIDLAKKEIAKTNRAVVVEGYTDVMACHLAGITTAIATCGTAFGEGHIKILRRLLMDNSGSEVVFTFDGDAAGQKAALRAFEDDQKFAAETSIAITPGGMDPCDLRLAKGDQAVADLVESRTPLFEFALRHVVSRHNLDTPVGRAAALDEAAPIVARIKNSAIQHESAVQLAGILGILDTQFVVRRVSQLARWARERGRDGGPGQGRPQRREAPSAAEPQRPAPGAGGPALNLRSPAHRVERELLKLALQRPDLVSPAFDAYGADEFTAPPYAVVRQCIEEAGGATTGSADGDFLARVRDAAPDDTVRAMVTELAVEPLHTRRDPDEVYAGVQLVAVRLAAVNQRVMEIRGTLQRLGPRADPEQLTAVQNELWVLQQYGQSLRERGAAAL
>NZ_CP006871.1|WP_016576178.1|3642562_3643582_-|threo-3-hydroxy-L-aspartate-ammonia-lyase
MTSGPTSTNRSTGGADPDASGTPDVTLDDVREAARRLAGAAHRTPVLRSRTLDARTGTQAFLKCENFQRAGAFKFRGAYHALSRLTPEERAGGVVAYSSGNHAQAVALAARERGTRAVIVMPADAPRSKRDATAGYGAEIITYDRYTEDRVALGRRIAEERGLTLIPPYDHPHVIAGQGTTALELLDETGPLDALLVPVGGGGLMAGVATAATALAPGIRMIGVEPAAGDDTRRSLAAGHRVAVPVPRTIADGQAAETPGELTFAINRRLVDSVLLVTDDEIRTAMAFAFERLKIVVEPSGATALAALLAGHLEHPPARTGVIVSGGNIAPDRFRELLG
>NZ_CP006871.1|WP_020931365.1|3644546_3645809_-|ferredoxin
MVDTHQTFVIVGGGLAGAKAAETLRAEGFTGRVILICDERDHPYERPPLSKGYLLGKEERDSVFVHEPAFYAQARIELHLGQPAVHLDPAARTVRLGDGTLIAYDKLLLATGAEPRRLDVPGTGLAGVHHLRRLAHAERLRGVLASLGRENGHLVIAGAGWIGLEVAAAARSYGAEVTIIEPEPTPLHGILGPELGALFTDLHAEHGVRFHFGARLTEIVGQDGMVVSVRTDDGEEHPAHDVLAAIGAAPRTALAEQAGLDVVDRADGGGIAVDAALRTSDPFIHAAGDVAAADHPLLDTRLRVEHWANALNGGPAAARAMLGQDISYDRVPYFFSDQYDLGMEYSGYAPPGSYDQVVCRGDVGKREFIAFWLREGRVLAGMNVNVWDVAGDVQQLIRSGTPLDPEKLADPTVPLTSLLP
>NZ_CP006871.1|WP_020931364.1|3646032_3647400_-|deoxyguanosinetriphosphate-triphosphohydrolase
MTGTTRATPPSPGQEPHAAPPGYTAADTERWVPEPDKRPGRTAFQRDRARVLHSAALRRLAGKTQVVTPGSATQAWDASPRTRLTHSLECAQVGRELGAALGCDPDLVEVACLAHDLGHPPFGHNGEQALNEVAAPCGGFEGNAQSLRLLARLEPKRFVPSPDGAPVSVGLNLTRAALDAATKYPWPRGAHPDGPTLPKFGVYADDLPVFAWFRQGAPSAGRSFEAQVMDWSDDVAYSVHDVEDGLHAGHLDPNVLLADPERAEIFAVAAERYAPGAGAAELAAALDRLLEQEWWPHGYDGSALAQARLKDATSQLIGRFCQAAEEATRARWGHPPYRPGPGGGGTRLTRYAAELVVPAETRLECAVLKAVADRYVIQRPDQEALRADQRVVIAELAEALLARAPDGLDPQFRSLFDAAPDDSARMRAVIDQIAALTDASARTLHARLTRPPGNG
>NZ_CP006871.1|WP_063789840.1|3647426_3648410_-|hypothetical-protein
MTASTTNHPTPEPSPAAPPPPPDPRPRPADPLGAAGLACEITAELSSRLRTVRLHRFRRPTARPPALVAVAHGSRHPGAAPAVRALLARVRALRPGLPVHLGHLELDEPLLADTLAALRAAPAAPGSAVLVPLLFGHGHHVTRDLPAALAAAGHLNGRTASPLGPDTLLVEALHDRLLEAGFPTGPHRGHRPAVVLAAAGSRAARSARDTARTARLLSARLGGVPVLPGYAHPSPATVPDGDASRRPSSIAASLTVPEAVRALTDRGHRPRDIAVAACFAAPGRFADQCAALAPGPAAAPLGDHPALARLVLHRYDQALCARTGSGT
>NZ_CP006871.1|WP_016575073.1|3648571_3650734_+|molybdopterin-oxidoreductase
MDTVATAATATVETHCPYCALQCGMGLQPADGPDGPAVEVVPRPAFPVNRGALCGKGRTAPELLAPGARLTVPLVRDPVTGALVPADWDTALDRVAEGLRRTGAAYGRDAVGVFGGGGLTNEKAYALGKFARVVLGTSQIDYNGRFCMSSAAAAQGRAFGLDRGLPFPLADVARTGCVLLVGSNLAETMPPALRYLTELKENGGRLIVVDPRRTRTAEQADLHLAPRPGTDLALALGLLHLVVAEGRTDEEFVAARTRGWPAARAAAMAHWPELVERLTGVPVPQLREAVALFCDAPSSMVLTARGPEQQAKGTDTVGAWINLCLATGRAGRELSGYGCLTGQGNGQGGREHGQKADQLPGYRRLDDPAARHHVAGVWGVDPDALPGPGRSAYELLDALGGDVRALLLMGSNPVVSAPGAAHVEERIKALDFLVVADVVRSETAELADVVLPVAQWAEETGTTTNLEGRVLLRRRALDPPPGVRTDLEVLGGLAARLGHRTGFPADPEEVFEELRRASAGGPADYSGISYARIAAEDGVFWPCPAPPTRAVTGAQAARGEPAGVPDHPGTPRLFLDRFATPDGRARFVPVTHRPADEETDAGYPVVLTTGRVLAQYQSGAQTRRVTALNAAEPGPFVELHPRLADRLGVADGEPVAVVSRRGRAVAPARVSRAIRPDTVFMPFHWPGEGRANTLTNPALDPVSRMPEFKVCAVRIERLDG
>NZ_CP006871.1|WP_037637133.1|3650752_3651724_-|adenosine-deaminase
MPKAELHLHIEGTLEPGLAFALAERNGVTLPYATEDELRRAYSFADLQSFLNLYYALMEVLRTEDDFADLAHAYLARAKEQGVRHAEIFFDPQAHTARGIPLGTVINGLSRALDAAPETYGITTRLIMCFLRDESAESALATFEAARPYLDRITAVGLDSAEVGHPPAKFQEVFALAREAGLKCVAHAGEEGPAAYVWEALDLLGVDRVDHGVRCMEDERLVARLVAERIPLTVCPLSNVRLRVVDDLADHPLPAMLDAGLLVTINSDDPAYFGGYADDNFTAVRDALDLDEETLRTLARNSFLASFLDEETRAAYLKELDAS
>NZ_CP006871.1|WP_016574528.1|3651871_3652327_-|gamma-glutamylcyclotransferase
MTPEAEHLPFFVYGTLRPGEANYARTLRGRTAAEEPARIAGALLYEGPGYPYATAGPADAVVHGALVRPRDADYDAVRAALDLLEGYTPGAPAGAGNLYERVATEAVCTDGRAVRAWVYLAAEPLATRLRATGTPITGGQWTGRAAPRSPR

Crispr_ID: NZ_CP006871_2

• CRISPR_ID: NZ_CP006871_2
• CRISPR_location: 3723296-3723478
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP006871_2

Consensus_repeat	Method
CCCGCCGCTCCGGCGTGCGGAGCGGCGGGGCCGCGCGGGAG	PILER-CR
CGGACCGGCGGGGCCGCGCGGGAG	CRISPRCasFinder

spacers of NZ_CP006871_2

>2.1|3723337|41|NZ_CP006871|PILER-CR
CCGCCCGCCCCGTCTCCCGCTCGGGCCGGCCGCTCCGCACG
>2.2|3723419|42|NZ_CP006871|PILER-CR
GGGGGGGGAATTGGTTAGGGAAGGTGTCGGGAGGCGCGGGGC
>2.3|3723337|35|NZ_CP006871|CRISPRCasFinder
CCCCGTCTCCCGCTCGGGCCGGCCGCTCCGCACGC
>2.4|3723396|59|NZ_CP006871|CRISPRCasFinder
GGGGGGGGAATTGGTTAGGGAAGGTGTCGGGAGGCGCGGGGCCCCGCCGCTCCGGCGTG

CRISPR arrays and Neighbor proteins around NZ_CP006871_2

CRISPR arrays

The CRISPR arrays of NZ_CP006871_2

>merge|NZ_CP006871|2|3723296-3723478|PILER-CR,CRISPRCasFinder
CCCGCCGCTCCGGCGTGCGGAGCGGCGGGGCCGCCCGCCCGCCCCGTCTCCCGCTCGGGCCGGCCGCTCCGCACGCCGGACCGGCGGGGCCGCGCGGGAGGGGGGGGGAATTGGTTAGGGAAGGTGTCGGGAGGCGCGGGGCCCCGCCGCTCCGGCGTGCGGAGCGGCGGGGCCGCGCGGGAG

>NZ_CP006871|2|1|3723296-3723478|PILER-CR
CCCGCCGCTCCGGCGTGCGGAGCGGCGGGGCCGCCCGCCCG	CCCCGTCTCCCGCTCGGGCCGGCCGCTCCGCACGCCGGACC
GGCGGGGCCGCGCGGGAGGGGGGGGGAATTGGTTAGGGAAG	GTGTCGGGAGGCGCGGGGCCCCGCCGCTCCGGCGTGCGGAGC
GGCGGGGCCGCGCGGGAG

>NZ_CP006871|2|2|3723313-3723478|CRISPRCasFinder
CGGAGCGGCGGGGCCGCCCGCCCG	CCCCGTCTCCCGCTCGGGCCGGCCGCTCCGCACGC
CGGACCGGCGGGGCCGCGCGGGAG	GGGGGGGGAATTGGTTAGGGAAGGTGTCGGGAGGCGCGGGGCCCCGCCGCTCCGGCGTG
CGGAGCGGCGGGGCCGCGCGGGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_037632337.1|3730120_3730483_-|hypothetical-protein	unknown	unknown	gnl|CDD|273572
NZ_CP006871.1|WP_016574970.1|3731269_3732589_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NZ_CP006871.1|WP_016574969.1|3732600_3733098_-|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl|CDD|234575
NZ_CP006871.1|WP_016573759.1|3723494_3725252_-|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|235154
NZ_CP006871.1|WP_020929295.1|3733137_3734139_-|PhoH-family-protein	unknown	unknown	gnl|CDD|224616
NZ_CP006871.1|WP_016575337.1|3720974_3722207_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP006871.1|WP_020929294.1|3729076_3730015_-|GTPase-Era	unknown	unknown	gnl|CDD|234624
NZ_CP006871.1|WP_016575339.1|3719047_3719632_+|putative-ATP/GTP-binding-protein	unknown	unknown	gnl|CDD|225138
NZ_CP006871.1|WP_016575343.1|3715371_3716118_-|DNA-repair-protein-RecO	unknown	unknown	gnl|CDD|234622
NZ_CP006871.1|WP_020931091.1|3712756_3714379_+|amidohydrolase	unknown	unknown	gnl|CDD|238625
NZ_CP006871.1|WP_016575341.1|3718237_3718666_+|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|367422
NZ_CP006871.1|WP_016574967.1|3734323_3735520_-|carbohydrate-kinase	unknown	unknown	gnl|CDD|238917
NZ_CP006871.1|WP_016575342.1|3716759_3718241_+|kinase	unknown	unknown	gnl|CDD|340391
NZ_CP006871.1|WP_037636610.1|3714475_3715294_-|isoprenyl-transferase	unknown	unknown	gnl|CDD|237826
NZ_CP006871.1|WP_016578229.1|3722356_3723076_-|hypothetical-protein	unknown	unknown	gnl|CDD|377455
NZ_CP006871.1|WP_044375230.1|3725543_3726635_+|peptidase-M4-family-protein	unknown	unknown	gnl|CDD|341060
NZ_CP006871.1|WP_016575338.1|3719628_3721059_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP006871.1|WP_016577594.1|3726728_3726995_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016577562.1|3727092_3728463_+|beta-glucosidase	unknown	unknown	gnl|CDD|274539
NZ_CP006871.1|WP_016575340.1|3718662_3719025_+|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_037632337.1|3730120_3730483_-|hypothetical-protein	gnl|CDD|273572	TIGR01354, Cytidine_deaminase, cytidine deaminase, homotetrameric. This small, homotetrameric zinc metalloprotein is found in humans and most bacteria. A related, homodimeric form with a much larger subunit is found in E. coli and in Arabidopsis. Both types may act on deoxycytidine as well as cytidine. [Purines, pyrimidines, nucleosides, and nucleotides, Salvage of nucleosides and nucleotides].	7.15375e-06
NZ_CP006871.1|WP_016574970.1|3731269_3732589_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	6.01181e-91
NZ_CP006871.1|WP_016573759.1|3723494_3725252_-|2-isopropylmalate-synthase	gnl|CDD|235154	PRK03739, PRK03739, 2-isopropylmalate synthase; Validated.	0
NZ_CP006871.1|WP_020929295.1|3733137_3734139_-|PhoH-family-protein	gnl|CDD|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	4.95417e-139
NZ_CP006871.1|WP_016575337.1|3720974_3722207_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.39111e-80
NZ_CP006871.1|WP_020929294.1|3729076_3730015_-|GTPase-Era	gnl|CDD|234624	PRK00089, era, GTPase Era; Reviewed.	3.3877e-161
NZ_CP006871.1|WP_016575339.1|3719047_3719632_+|putative-ATP/GTP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	6.83487e-37
NZ_CP006871.1|WP_016575343.1|3715371_3716118_-|DNA-repair-protein-RecO	gnl|CDD|234622	PRK00085, recO, DNA repair protein RecO; Reviewed.	2.3838e-85
NZ_CP006871.1|WP_020931091.1|3712756_3714379_+|amidohydrolase	gnl|CDD|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	7.49253e-127
NZ_CP006871.1|WP_016575341.1|3718237_3718666_+|roadblock/LC7-domain-containing-protein	gnl|CDD|367422	pfam03259, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	3.24769e-15
NZ_CP006871.1|WP_016574967.1|3734323_3735520_-|carbohydrate-kinase	gnl|CDD|238917	cd01942, ribokinase_group_A, Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	4.78839e-49
NZ_CP006871.1|WP_016575342.1|3716759_3718241_+|kinase	gnl|CDD|340391	cd00075, HATPase, Histidine kinase-like ATPase domain. This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.	9.54189e-15
NZ_CP006871.1|WP_037636610.1|3714475_3715294_-|isoprenyl-transferase	gnl|CDD|237826	PRK14829, PRK14829, undecaprenyl pyrophosphate synthase; Provisional.	1.97501e-141
NZ_CP006871.1|WP_016578229.1|3722356_3723076_-|hypothetical-protein	gnl|CDD|377455	pfam05099, TerB, Tellurite resistance protein TerB. This family contains the TerB tellurite resistance proteins from a a number of bacteria.	0.00705353
NZ_CP006871.1|WP_044375230.1|3725543_3726635_+|peptidase-M4-family-protein	gnl|CDD|341060	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease. This peptidase M4 family includes several endopeptidases such as thermolysin (EC 3.4.24.27), aureolysin (the extracellular metalloproteinase from Staphylococcus aureus), neutral protease from Bacillus cereus, protealysin, and bacillolysin (EC 3.4.24.28). Typically, the M4 peptidases consist of a presequence (signal sequence), a propeptide sequence, and a peptidase unit. The presequence is cleaved off during export while the propeptide has inhibitory and chaperone functions and facilitates folding. The propeptide remains attached until the peptidase is secreted and can be safely activated. All peptidases in this family bind a single catalytic zinc ion which is tetrahedrally co-ordinated by three amino acid ligands and a water molecule that forms the nucleophile on activation during catalysis. The active site is found between two sub-domains; the N-terminal domain contains the HEXXH zinc-binding motif while the helical C-terminal domain, which is unique for the family, carries the third zinc ligand. These peptidases are secreted eubacterial endopeptidases from Gram-positive or Gram-negative sources that degrade extracellular proteins and peptides for bacterial nutrition. They are selectively inhibited by Steptomyces metalloproteinase inhibitor (SMPI) as well as by phosphoramidon from Streptomyces tanashiensis. A large number of these enzymes are implicated as key factors in the pathogenesis of various diseases, including gastritis, peptic ulcer, gastric carcinoma, cholera and several types of bacterial infections, and are therefore important drug targets. Some enzymes of the family can function at extremes of temperatures, while some function in organic solvents, thus rendering them novel targets for biotechnological applications. Thermolysin is widely used as a nonspecific protease to obtain fragments for peptide sequencing. It has also been used in production of the artificial sweetener aspartame.	1.17852e-129
NZ_CP006871.1|WP_016575338.1|3719628_3721059_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.79053e-38
NZ_CP006871.1|WP_016574969.1|3732600_3733098_-|rRNA-maturation-RNase-YbeY	gnl|CDD|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	2.46675e-69
NZ_CP006871.1|WP_016577562.1|3727092_3728463_+|beta-glucosidase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	0
NZ_CP006871.1|WP_016575340.1|3718662_3719025_+|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	1.07189e-20

Protein sequences

>NZ_CP006871.1|WP_016578229.1|3722356_3723076_-|hypothetical-protein
MRNVRVVGVRTSWRTVADGEFFCPDCGGDRNYLRRTGRRRLHVLGVPVLARGDAGPVLECSACRGRFGLDALDHPTTVRLSTMLRDAVHTLTLALLAAGGTASRTVRDAAVTAVRAAGSADCTEDQLLTLLAALAADTGRMTGTYEAATGDHCGHQGLDPCGTALAIELHEALEPLAPHLAPAGRESLLLQAARIALADGPCTPAEREVLSTAGAALTLRPEDVDRLLLAAARSSRYRG
>NZ_CP006871.1|WP_016575337.1|3720974_3722207_+|cytochrome-P450
MAEQRPQPVVIDPAGTDIHGEGDRLRALGPAARIELPGGIQAWGVTGHALLKELLTDDRISKNPRDHWPEWQRPEIRGSWLQSWIGVTNMFTAYGADHRRLRKLIAPAFTARRTDAMVPRVTQIVGDLLDGLAARPAGEVVDLRESFNHPLPMQVICELFGYPEGAPRGELARVVSEIMDTTATPEQATATQAAVAELLGSLVATKRAQPADDLTSLLVAARDDEGQGMTERELLDTLLLVIGAGHETTVDLLGNAVFALLTHPEQLKLVRDGAVSWHDVIEETLRWTPSIASLPLRFAVQDVALPHGEVIRKGEALLPMYAAAGRDPEQHGPAAATFDVQRASQDHLAFGHGVHHCIGAPLARLEARTALPALFERFPDMQLAVPAEELQPAGGFIAGGLASLPVRLTA
>NZ_CP006871.1|WP_016575338.1|3719628_3721059_+|cytochrome-P450
MTSPYEPGAAPPPSACPGQAVPPSEAAAPPPGCPAHAGPQRAAAHPEAHAPVKLYGPDFAADPHRIYARLRQYGAVAPVEIAPEVPALLVTDYRAALELLNDDATWSKDSRAWMQTVPADSPVMPMLHWRPNVFYSDGPAHVRYRDAIVDSFKLVEPHELRARVHHAADTLIRRFGDRGEADLIADYARLIPLLMFNTLFGLPDSYSDRLIAAIAGMMEGNSPEEATAANEAYTQYIMELVGAKKAQRGPDLTSWMMDHANDLSDEELIHNIILVMGAGNEPLANLIGNALARMLSDDRYYNTVSGGALTVHDAINEVLWNDPPMANYSAHFPVRDVFFHGTWVRAGQLVMVSYAAANSQFDSTGAHGPESGSGSHLAWAAGPHACPVKRHALLIAITAIERLTAWLSDIELAVAPAELTWRNGAFHRALAALPARFTPITPDQAGATPWQNSDRSPSSSTRPAPTSTAKETASAH
>NZ_CP006871.1|WP_016575339.1|3719047_3719632_+|putative-ATP/GTP-binding-protein
MYLRGEDQTLVKLLVAGPFGVGKTTLIRALSETPPLHTEEVMTQSGAMVDDLAGVRDKTTTTVAIDFGRLTLPGDLVLYLFGTPGQKRFRPLWQDIARGALGALVLADTRRLADSFEVMDIVEEAGLRYAVAVNTFPDAPQYDVAKMREALDLHPDTPLVLCDARDREQSVDALIALVRHVLDHTPQPEENPKP
>NZ_CP006871.1|WP_016575340.1|3718662_3719025_+|DUF742-domain-containing-protein
MTPRQSSGRRLVPAYLATGGRARPSRNTLDRLTVLIGVDMPITSEVRPEEHRILELLQPGALTLAEVAAHLHLPVSVVKVLVADLVDAGRLHARVPIPEAEQFDRQILERVLDGLRSLKS
>NZ_CP006871.1|WP_016575341.1|3718237_3718666_+|roadblock/LC7-domain-containing-protein
MNSPTRRRVTEDKSWVLAPLLELPHVVHAAVISGDGFIEGASPGLSREAAEGVAAMMSALQGAGRAVTAAFTEQDDARLRQTVIESDEGFVFAIPAGENTCLAVFADPEVNMGVVAHHMQIQVTTLGKKVMNSPARDTGSHA
>NZ_CP006871.1|WP_016575342.1|3716759_3718241_+|kinase
MTSIPQALLWCLSAGTVAAVVLAALLVRVRKERAGLRARLTAAEEHSSATLHGNTELSARLRATEAEVRHLAEARLPDLTLALAHPHVPVRGLLDQRFGGSETDEALDAVMAQVSEAITKERTRVDAAAQSTLRGATTTIQALLYQVQTSLQAMQHKYDDPQIAQDLLDADFLNEQALRRVQATGVVCGAWPGLTREDSYLAELVVGATSRLRGYERVQVSNQLRDPVAVVARAVEPIAITVTELLANALHHSHRELPVTVTLQQGNRGASVIIDDYGVGMHDDELKHAMELLASNDGLLLTQLGDPPRSGFAAAGQLVRQYGFGVHVEPSPYGGVRAVVYIPGDPLLTVLDEGARPISVMAPMPHRAPGGPRDRAAVPSAMPTGASAPATPAGALPTPRPAAEAHAVPVQPAPARPVAEPAPQQPPVEGELPRRRRRRPQAEQQPESHPDTLNLRSPEETGSRWAALQRGTESGRAAAHSEPPRSPEGNAQS
>NZ_CP006871.1|WP_016575343.1|3715371_3716118_-|DNA-repair-protein-RecO
MTLFRDDGIVLRTQKLGEADRIITLLTRGNGRVRAVARGVRRTKSKFGARLEPFSHVDVQFFARGGELIGRGLPLCTQSETIAAYGGAIVTDYARYTAGTAMLETAERFTDHEGEPAVQQYLLLVGGLRTLANGEHAPHLVLDAFLLRSLAVNGYAPSFDACARCGMPGPNRFFSVASGGVVCGDCRVPGSVVPSSEAIGLLGALLTGDWETADACEARHVREGSGLVAAYLHWHLERGLRSLRYVEK
>NZ_CP006871.1|WP_037636610.1|3714475_3715294_-|isoprenyl-transferase
MAVRGILGRNRREYQTPEPHPSGARPPRIPGELVPNHVAVVMDGNGRWAKERGLPRTEGHKVGEGVVLDVLKGCIEMGVKNLSLYAFSTENWKRSPDEVRFLMNFNRDVIRRRRDEMDALGIRIRWVGRMPKLWKSVVQELQVAQEQTKNNDAMTLYFCVNYGGRAEIADAAAAIAADVRAGKLDPSKVNEKTVAKYMYYPDMPDVDLFVRPSGEQRTSNYLIWQSAYAEMVFQDILWPDFDRRNLWDACFEYAKRDRRFGAAPLEDGEQAT
>NZ_CP006871.1|WP_020931091.1|3712756_3714379_+|amidohydrolase
MPAALVLLSARLLDPVTGTFLPQTALAAADGKITALGDDREIRALADTATTVIDLKGAVVTPGLTDGHLHPVSGAELTHGLDLSGCTDLDGVRAALAREVAALAPGAWLHGWGLDPNVFGDRPIESAALAPVLDGVPALLQLFDAHSMLASPRALELAGVDGPRTFDQAAEVVCDDAGRPTGLLLEDAACELVERAAPQPTREERRARLAAALRAMAAAGLTGGHAMDANGDSLAFYDELDAAGDLPLRLRVAPWCQPGTDADGVRALIAQQGTGGRLWRTAGVKLFMDGTIDNGTAWLERPDCHGESTHAFWPDPAAYTRVIGQLHAAGVPTATHAIGDAAVRHALDAVEQARRADPNGVRHRIEHIETVPDDTLRRFAELGVLASMQPTHCCDFTRADHTDNWSRRLGEERAGRAWRCRDLTDAGATVVLGSDWPIAPYPPLGVMAGARHRRPTRDLAQPPHGPEQALTALEALRGMTVHAAHAAGEEDRAGRIVPGHRADLTVLADDPLTTPATDLPRLPVLLTVLDGRPTHRDRSL
>NZ_CP006871.1|WP_016573759.1|3723494_3725252_-|2-isopropylmalate-synthase
MSQPVGRPTPITNATHAQTSSGMPIHKYRPFEAVDLSARTWPAKRITKAPRWLSTDLRDGNQALIDPMSPARKREMFDLLVRLGYKEIEVGFPSSGETDFAFVRSIIEEGAIPDDVTISVLTQAREELIERTVEALRGAPRATVHLYNATAPTFRRVVFRGSKEQVKQIAVDGTRLVMEYADKLLGDETAFGYQYSPEIFTDTELDFALEVCEAVMDVWQPEAGREIILNLPATVERSTPSTHADRFEWMSRNLSRREFVCLSTHPHNDRGTAVAAAELAVMAGADRVEGCLFGQGERTGNVDLVTLGMNLFSQGVDPQIDFSQIDEIRRTSEYCNQMEVHPRHPYAGDLVYTAFSGSHQDAIKKGFDALEADAAAQGKTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHKLDLPRRMQIEFSRIIQEKTDAEGGEVTPKAIWDTFRDEYLPNPQNPWGRIQVRTGQTTTDKDGVDTLTVEAEVDGVETVLTGSGNGPISAFFDALSGLGIDARLLDYQEHTMSEGASAQAASYIECAIDGKVLWGIGIDANTTRASLKAVVSAVNRSAR
>NZ_CP006871.1|WP_044375230.1|3725543_3726635_+|peptidase-M4-family-protein
MKETVTQKRTAPAPTTPVFCTIVPPHILGKLAESDDPGHHEPARRTLEHDALHRTRRTDLAAQSLIPQEARAAADKPNRTIYDAGHQQNLPGTKVHAESDAPSKDASVNRAHAGLGATFELYLKVYGRKSIDGAGLPLDATVHYGEKYDNAFWDGQRMVFGDGDGTLFKDFTIPVDVIGHELTHGVTQYTANLDYQGQSGALNESVSDVFGSLIKQYALGQSADQADWLIGADLLAPGVHGQALRSMKAPGTAYDDPQLGKDPQPATMAGYVQTSEDNGGVHLNSGIPNHAFYLVASALGGKAWERAGQIWYDVLTGGHLTKNAQFADFANLTVQAAQTRYGASGSEHEAVVKAWSTVGVTGK
>NZ_CP006871.1|WP_016577594.1|3726728_3726995_+|hypothetical-protein
MRIHIRRTGGFAGIERHAEIDTADRTDATDWHGLADRAMTAAHTAPPTGVPDGFRYALTVDDKTAYCTDPDLTDDQRELITRVLKEGE
>NZ_CP006871.1|WP_016577562.1|3727092_3728463_+|beta-glucosidase
MTPEPARAPAPPPAPLRFPRGFLWGVSTSAAQIEGAVDEDGRGPSSWDAFAAGAGRIKDGSDPRVTTDHYHRYQEDVALLKDLGVGAYRFSVAWPRVVPEGRGAVNAAGLDFYDRLVDALLAAGVAPVPTLFHWDTPQALEASGGWLQRETAEHFAAYADAVAARLGDRVTRWITLNEPAEVTLLGYGLGQHAPGRHLLFDALPAAHHQLLGHGLAVQALRARGATGIGIANSHGPTWPASDSPADTEAADLYDLLLNRLFAEPILLGRYPDDEIAALLPGPVTDDLTTISAPLDWYGINYYQPTKIGAPTTEETDFSGVRLPPGLPFTPREITDRPRTGFGWPVVPEALTELLLSFHDRYGADLPPVMITENGCAYDGIEDPERIAFLDGHLRALRTAMDAGVDVRGYFVWSLLDNFEWAEGFRQRFGLVHVDYTTLRRTPKASFRWLREVVAQT
>NZ_CP006871.1|WP_020929294.1|3729076_3730015_-|GTPase-Era
MSVRTESTAPHRAGFACFVGRPNAGKSTLTNALVGTKVAITSNRPQTTRHTVRGIVHRPDAQLVLVDTPGLHKPRTLLGERLNDVVRTTWSEVDVIGFCLPADQKLGPGDRYIASELAEIKKTPKIAIVTKTDLVDSKALATQLLAIDRLGKELGIEWAEIIPVSAVGDQQVSLLADLLVPLLPEGPALYPEGDLTDEPEQVMVAELIREAALEGVRDELPHSIAVVVEEMLPREDRPADKPLLDIHANVYIERPSQKGIIIGPKGKRLKEVGTKSRKHIEALLGTPVFLDLHVKVAKDWQRDPKQLRKLGF
>NZ_CP006871.1|WP_037632337.1|3730120_3730483_-|hypothetical-protein
MTEAAPLDPEDRKIITLARSARARNGVPEGAAVRDETGRTYVAGTVALDSLQLSALQTAVAMAVASGATSLEAAAVVTDADQAADADRAAVRDLGGPDTPVLVAAPDGTLRAATPAGPAA
>NZ_CP006871.1|WP_016574970.1|3731269_3732589_-|HlyC/CorC-family-transporter
MTTLIAVAVLLVVVAWLAACAEAGLTRTTSFRAEEAVRSGRRGSAKLAAVAADPTRYLNVALLVRVGCEMAAGALVTYACLRSFDTTWEALTVAIAVMVLVSYVAVGVSPRTIGRQHPLNTATAAAYVLLPLARVMGPVPQLLILLGNALTPGKGFRKGPFASEAELRSLVDLAEKESLIEDEERRMVHSVFQLGDTLVREVMVPRTDLISVERFKTIRQALTLALRSGFSRIPVTGENEDDVVGVVYLKDLARKVHISRDAETDLVSTAMRPAVFVPDTKNAGDLLREMQRDRNHVAVVIDEYGGTAGIITIEDILEEIVGEITDEYDRELPPVQDLGGGRYRVTARLDIGALGELYGLAELDDEDVETVGGLLAKQLGRVPIAGATVEIDLSEHASDPDLKALRLIAEAPAGRRNKIVTVLCEPVRAAEAEGDGAGG
>NZ_CP006871.1|WP_016574969.1|3732600_3733098_-|rRNA-maturation-RNase-YbeY
MSIDVNNESGTDIDEQAILDVARYALARMRIHPLSELSVIVVDAEAMEQLHIQWMDLPGPTDVMSFPMDELRPPAKDDEEPPQGLLGDIVLCPEVAEQQGKAAPTGHTMDEELQLLTVHGVLHLLGYDHEEPDEKAEMFGLQAAIVDGWRAERGMTGPSPAPTVT
>NZ_CP006871.1|WP_020929295.1|3733137_3734139_-|PhoH-family-protein
MTQTPTRAQASAHFTVPAKHPMVTVLGSGDSLLRVIEDAFPATDIHVRGNEISAVGDAREVALVQRLFDEMMLVLRTGQPMTEDAVERSIAMLRAAENGEGASETPAEVLTQNILSNRGRTIRPKTLNQKRYVDAIDKHTIVFGIGPAGTGKTYLAMAKAVQALQAKQVNRIILTRPAVEAGERLGFLPGTLYEKIDPYLRPLYDALHDMLDPDSIPRLMAAGTIEVAPLAYMRGRTLNDAFIILDEAQNTNPEQMKMFLTRLGFESKIVITGDVTQIDLPGGTKSGLRQVRDILTDVDDVHFSELTSRDVVRHKLVGRIVDAYEKYDSRNGK
>NZ_CP006871.1|WP_016574967.1|3734323_3735520_-|carbohydrate-kinase
MNTGRRDVQPPAGPATEPPGLDPLAAVRRAGDPPTDVYLTGTVFLDIIFTGLDSAPVRGTESWARGMGSSPGGVANMATALARLGLRTSLAAAFGDDMYGEYCWEALERGEGIDLELSRTVPGWHSPVTVSMAYEGERTMVSHGHEAPAPEHAFDGGHAPGCPPPTRACVASLVPGRREGWLGCAAGRGSRIFADVGWDDTGRWDPADLADLEHCEAFLPNAEEAMRYTRTDCPRAAARKLADLVPLAVVTLGSEGACAVDARTGESAEVPAIVVEALDPTGAGDVFVAGFVTGTLADWPLADRLSFAGLSAALSVQEFGGSLSAPGWAEIAAWWRRVRACDTGATAGLRRQYGFLDAVLPAPGVSLGSTGAAGPARAAAAASPLARAVPTIGFRPPA

Crispr_ID: NZ_CP006871_3

• CRISPR_ID: NZ_CP006871_3
• CRISPR_location: 3728483-3728581
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP006871_3

Consensus_repeat	Method
GTCGGCCGTCCCGCCGTGGGGGTT	CRISPRCasFinder

spacers of NZ_CP006871_3

>3.1|3728507|51|NZ_CP006871|CRISPRCasFinder
TCTGTTTGCGCCTGCGGCGCGTTGCCGCTGCGCGGGGCGTCGTCGTACGTC

CRISPR arrays and Neighbor proteins around NZ_CP006871_3

CRISPR arrays

The CRISPR arrays of NZ_CP006871_3

>merge|NZ_CP006871|3|3728483-3728581|CRISPRCasFinder
GTCGGCCGTCCCGCCGTGGGGGTTTCTGTTTGCGCCTGCGGCGCGTTGCCGCTGCGCGGGGCGTCGTCGTACGTCGTCGGCTGTCCCGCCGTGGGGGTT

>NZ_CP006871|3|3|3728483-3728581|CRISPRCasFinder
GTCGGCCGTCCCGCCGTGGGGGTT	TCTGTTTGCGCCTGCGGCGCGTTGCCGCTGCGCGGGGCGTCGTCGTACGTC
GTCGGCTGTCCCGCCGTGGGGGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_037632337.1|3730120_3730483_-|hypothetical-protein	unknown	unknown	gnl|CDD|273572
NZ_CP006871.1|WP_016574969.1|3732600_3733098_-|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl|CDD|234575
NZ_CP006871.1|WP_016573759.1|3723494_3725252_-|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|235154
NZ_CP006871.1|WP_020929295.1|3733137_3734139_-|PhoH-family-protein	unknown	unknown	gnl|CDD|224616
NZ_CP006871.1|WP_016574966.1|3735587_3736928_+|6-phospho-beta-glucosidase	unknown	unknown	gnl|CDD|133432
NZ_CP006871.1|WP_016575337.1|3720974_3722207_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP006871.1|WP_016574970.1|3731269_3732589_-|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NZ_CP006871.1|WP_016575339.1|3719047_3719632_+|putative-ATP/GTP-binding-protein	unknown	unknown	gnl|CDD|225138
NZ_CP006871.1|WP_016578229.1|3722356_3723076_-|hypothetical-protein	unknown	unknown	gnl|CDD|377455
NZ_CP006871.1|WP_016575341.1|3718237_3718666_+|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|367422
NZ_CP006871.1|WP_016574967.1|3734323_3735520_-|carbohydrate-kinase	unknown	unknown	gnl|CDD|238917
NZ_CP006871.1|WP_016573928.1|3737786_3738872_-|S-(hydroxymethyl)mycothiol-dehydrogenase	unknown	unknown	gnl|CDD|132492
NZ_CP006871.1|WP_016573927.1|3737157_3737787_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293792
NZ_CP006871.1|WP_016573929.1|3739055_3740363_-|mandelate-racemase	unknown	unknown	gnl|CDD|239439
NZ_CP006871.1|WP_020929294.1|3729076_3730015_-|GTPase-Era	unknown	unknown	gnl|CDD|234624
NZ_CP006871.1|WP_044375230.1|3725543_3726635_+|peptidase-M4-family-protein	unknown	unknown	gnl|CDD|341060
NZ_CP006871.1|WP_016575338.1|3719628_3721059_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP006871.1|WP_016577594.1|3726728_3726995_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016577562.1|3727092_3728463_+|beta-glucosidase	unknown	unknown	gnl|CDD|274539
NZ_CP006871.1|WP_016575340.1|3718662_3719025_+|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_037632337.1|3730120_3730483_-|hypothetical-protein	gnl|CDD|273572	TIGR01354, Cytidine_deaminase, cytidine deaminase, homotetrameric. This small, homotetrameric zinc metalloprotein is found in humans and most bacteria. A related, homodimeric form with a much larger subunit is found in E. coli and in Arabidopsis. Both types may act on deoxycytidine as well as cytidine. [Purines, pyrimidines, nucleosides, and nucleotides, Salvage of nucleosides and nucleotides].	7.15375e-06
NZ_CP006871.1|WP_016573759.1|3723494_3725252_-|2-isopropylmalate-synthase	gnl|CDD|235154	PRK03739, PRK03739, 2-isopropylmalate synthase; Validated.	0
NZ_CP006871.1|WP_020929295.1|3733137_3734139_-|PhoH-family-protein	gnl|CDD|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	4.95417e-139
NZ_CP006871.1|WP_016574966.1|3735587_3736928_+|6-phospho-beta-glucosidase	gnl|CDD|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	1.16476e-180
NZ_CP006871.1|WP_016575337.1|3720974_3722207_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.39111e-80
NZ_CP006871.1|WP_016574970.1|3731269_3732589_-|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	6.01181e-91
NZ_CP006871.1|WP_016575339.1|3719047_3719632_+|putative-ATP/GTP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	6.83487e-37
NZ_CP006871.1|WP_016578229.1|3722356_3723076_-|hypothetical-protein	gnl|CDD|377455	pfam05099, TerB, Tellurite resistance protein TerB. This family contains the TerB tellurite resistance proteins from a a number of bacteria.	0.00705353
NZ_CP006871.1|WP_016575341.1|3718237_3718666_+|roadblock/LC7-domain-containing-protein	gnl|CDD|367422	pfam03259, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	3.24769e-15
NZ_CP006871.1|WP_016574967.1|3734323_3735520_-|carbohydrate-kinase	gnl|CDD|238917	cd01942, ribokinase_group_A, Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	4.78839e-49
NZ_CP006871.1|WP_016573928.1|3737786_3738872_-|S-(hydroxymethyl)mycothiol-dehydrogenase	gnl|CDD|132492	TIGR03451, S-hydroxymethylmycothiol_dehydrogenase, S-(hydroxymethyl)mycothiol dehydrogenase. Members of this protein family are mycothiol-dependent formaldehyde dehydrogenase (EC 1.2.1.66). This protein is found, so far, only in the Actinobacteria (Mycobacterium sp., Streptomyces sp., Corynebacterium sp., and related species), where mycothione replaces glutathione. [Cellular processes, Detoxification].	0
NZ_CP006871.1|WP_016573927.1|3737157_3737787_-|MBL-fold-metallo-hydrolase	gnl|CDD|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	2.87858e-51
NZ_CP006871.1|WP_016573929.1|3739055_3740363_-|mandelate-racemase	gnl|CDD|239439	cd03323, D-glucarate_dehydratase, D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and that is stabilized by coordination to the essential Mg2+ ion.	0
NZ_CP006871.1|WP_020929294.1|3729076_3730015_-|GTPase-Era	gnl|CDD|234624	PRK00089, era, GTPase Era; Reviewed.	3.3877e-161
NZ_CP006871.1|WP_044375230.1|3725543_3726635_+|peptidase-M4-family-protein	gnl|CDD|341060	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease. This peptidase M4 family includes several endopeptidases such as thermolysin (EC 3.4.24.27), aureolysin (the extracellular metalloproteinase from Staphylococcus aureus), neutral protease from Bacillus cereus, protealysin, and bacillolysin (EC 3.4.24.28). Typically, the M4 peptidases consist of a presequence (signal sequence), a propeptide sequence, and a peptidase unit. The presequence is cleaved off during export while the propeptide has inhibitory and chaperone functions and facilitates folding. The propeptide remains attached until the peptidase is secreted and can be safely activated. All peptidases in this family bind a single catalytic zinc ion which is tetrahedrally co-ordinated by three amino acid ligands and a water molecule that forms the nucleophile on activation during catalysis. The active site is found between two sub-domains; the N-terminal domain contains the HEXXH zinc-binding motif while the helical C-terminal domain, which is unique for the family, carries the third zinc ligand. These peptidases are secreted eubacterial endopeptidases from Gram-positive or Gram-negative sources that degrade extracellular proteins and peptides for bacterial nutrition. They are selectively inhibited by Steptomyces metalloproteinase inhibitor (SMPI) as well as by phosphoramidon from Streptomyces tanashiensis. A large number of these enzymes are implicated as key factors in the pathogenesis of various diseases, including gastritis, peptic ulcer, gastric carcinoma, cholera and several types of bacterial infections, and are therefore important drug targets. Some enzymes of the family can function at extremes of temperatures, while some function in organic solvents, thus rendering them novel targets for biotechnological applications. Thermolysin is widely used as a nonspecific protease to obtain fragments for peptide sequencing. It has also been used in production of the artificial sweetener aspartame.	1.17852e-129
NZ_CP006871.1|WP_016575338.1|3719628_3721059_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.79053e-38
NZ_CP006871.1|WP_016574969.1|3732600_3733098_-|rRNA-maturation-RNase-YbeY	gnl|CDD|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	2.46675e-69
NZ_CP006871.1|WP_016577562.1|3727092_3728463_+|beta-glucosidase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	0
NZ_CP006871.1|WP_016575340.1|3718662_3719025_+|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	1.07189e-20

Protein sequences

>NZ_CP006871.1|WP_016577562.1|3727092_3728463_+|beta-glucosidase
MTPEPARAPAPPPAPLRFPRGFLWGVSTSAAQIEGAVDEDGRGPSSWDAFAAGAGRIKDGSDPRVTTDHYHRYQEDVALLKDLGVGAYRFSVAWPRVVPEGRGAVNAAGLDFYDRLVDALLAAGVAPVPTLFHWDTPQALEASGGWLQRETAEHFAAYADAVAARLGDRVTRWITLNEPAEVTLLGYGLGQHAPGRHLLFDALPAAHHQLLGHGLAVQALRARGATGIGIANSHGPTWPASDSPADTEAADLYDLLLNRLFAEPILLGRYPDDEIAALLPGPVTDDLTTISAPLDWYGINYYQPTKIGAPTTEETDFSGVRLPPGLPFTPREITDRPRTGFGWPVVPEALTELLLSFHDRYGADLPPVMITENGCAYDGIEDPERIAFLDGHLRALRTAMDAGVDVRGYFVWSLLDNFEWAEGFRQRFGLVHVDYTTLRRTPKASFRWLREVVAQT
>NZ_CP006871.1|WP_016577594.1|3726728_3726995_+|hypothetical-protein
MRIHIRRTGGFAGIERHAEIDTADRTDATDWHGLADRAMTAAHTAPPTGVPDGFRYALTVDDKTAYCTDPDLTDDQRELITRVLKEGE
>NZ_CP006871.1|WP_044375230.1|3725543_3726635_+|peptidase-M4-family-protein
MKETVTQKRTAPAPTTPVFCTIVPPHILGKLAESDDPGHHEPARRTLEHDALHRTRRTDLAAQSLIPQEARAAADKPNRTIYDAGHQQNLPGTKVHAESDAPSKDASVNRAHAGLGATFELYLKVYGRKSIDGAGLPLDATVHYGEKYDNAFWDGQRMVFGDGDGTLFKDFTIPVDVIGHELTHGVTQYTANLDYQGQSGALNESVSDVFGSLIKQYALGQSADQADWLIGADLLAPGVHGQALRSMKAPGTAYDDPQLGKDPQPATMAGYVQTSEDNGGVHLNSGIPNHAFYLVASALGGKAWERAGQIWYDVLTGGHLTKNAQFADFANLTVQAAQTRYGASGSEHEAVVKAWSTVGVTGK
>NZ_CP006871.1|WP_016573759.1|3723494_3725252_-|2-isopropylmalate-synthase
MSQPVGRPTPITNATHAQTSSGMPIHKYRPFEAVDLSARTWPAKRITKAPRWLSTDLRDGNQALIDPMSPARKREMFDLLVRLGYKEIEVGFPSSGETDFAFVRSIIEEGAIPDDVTISVLTQAREELIERTVEALRGAPRATVHLYNATAPTFRRVVFRGSKEQVKQIAVDGTRLVMEYADKLLGDETAFGYQYSPEIFTDTELDFALEVCEAVMDVWQPEAGREIILNLPATVERSTPSTHADRFEWMSRNLSRREFVCLSTHPHNDRGTAVAAAELAVMAGADRVEGCLFGQGERTGNVDLVTLGMNLFSQGVDPQIDFSQIDEIRRTSEYCNQMEVHPRHPYAGDLVYTAFSGSHQDAIKKGFDALEADAAAQGKTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLKNDHKLDLPRRMQIEFSRIIQEKTDAEGGEVTPKAIWDTFRDEYLPNPQNPWGRIQVRTGQTTTDKDGVDTLTVEAEVDGVETVLTGSGNGPISAFFDALSGLGIDARLLDYQEHTMSEGASAQAASYIECAIDGKVLWGIGIDANTTRASLKAVVSAVNRSAR
>NZ_CP006871.1|WP_016578229.1|3722356_3723076_-|hypothetical-protein
MRNVRVVGVRTSWRTVADGEFFCPDCGGDRNYLRRTGRRRLHVLGVPVLARGDAGPVLECSACRGRFGLDALDHPTTVRLSTMLRDAVHTLTLALLAAGGTASRTVRDAAVTAVRAAGSADCTEDQLLTLLAALAADTGRMTGTYEAATGDHCGHQGLDPCGTALAIELHEALEPLAPHLAPAGRESLLLQAARIALADGPCTPAEREVLSTAGAALTLRPEDVDRLLLAAARSSRYRG
>NZ_CP006871.1|WP_016575337.1|3720974_3722207_+|cytochrome-P450
MAEQRPQPVVIDPAGTDIHGEGDRLRALGPAARIELPGGIQAWGVTGHALLKELLTDDRISKNPRDHWPEWQRPEIRGSWLQSWIGVTNMFTAYGADHRRLRKLIAPAFTARRTDAMVPRVTQIVGDLLDGLAARPAGEVVDLRESFNHPLPMQVICELFGYPEGAPRGELARVVSEIMDTTATPEQATATQAAVAELLGSLVATKRAQPADDLTSLLVAARDDEGQGMTERELLDTLLLVIGAGHETTVDLLGNAVFALLTHPEQLKLVRDGAVSWHDVIEETLRWTPSIASLPLRFAVQDVALPHGEVIRKGEALLPMYAAAGRDPEQHGPAAATFDVQRASQDHLAFGHGVHHCIGAPLARLEARTALPALFERFPDMQLAVPAEELQPAGGFIAGGLASLPVRLTA
>NZ_CP006871.1|WP_016575338.1|3719628_3721059_+|cytochrome-P450
MTSPYEPGAAPPPSACPGQAVPPSEAAAPPPGCPAHAGPQRAAAHPEAHAPVKLYGPDFAADPHRIYARLRQYGAVAPVEIAPEVPALLVTDYRAALELLNDDATWSKDSRAWMQTVPADSPVMPMLHWRPNVFYSDGPAHVRYRDAIVDSFKLVEPHELRARVHHAADTLIRRFGDRGEADLIADYARLIPLLMFNTLFGLPDSYSDRLIAAIAGMMEGNSPEEATAANEAYTQYIMELVGAKKAQRGPDLTSWMMDHANDLSDEELIHNIILVMGAGNEPLANLIGNALARMLSDDRYYNTVSGGALTVHDAINEVLWNDPPMANYSAHFPVRDVFFHGTWVRAGQLVMVSYAAANSQFDSTGAHGPESGSGSHLAWAAGPHACPVKRHALLIAITAIERLTAWLSDIELAVAPAELTWRNGAFHRALAALPARFTPITPDQAGATPWQNSDRSPSSSTRPAPTSTAKETASAH
>NZ_CP006871.1|WP_016575339.1|3719047_3719632_+|putative-ATP/GTP-binding-protein
MYLRGEDQTLVKLLVAGPFGVGKTTLIRALSETPPLHTEEVMTQSGAMVDDLAGVRDKTTTTVAIDFGRLTLPGDLVLYLFGTPGQKRFRPLWQDIARGALGALVLADTRRLADSFEVMDIVEEAGLRYAVAVNTFPDAPQYDVAKMREALDLHPDTPLVLCDARDREQSVDALIALVRHVLDHTPQPEENPKP
>NZ_CP006871.1|WP_016575340.1|3718662_3719025_+|DUF742-domain-containing-protein
MTPRQSSGRRLVPAYLATGGRARPSRNTLDRLTVLIGVDMPITSEVRPEEHRILELLQPGALTLAEVAAHLHLPVSVVKVLVADLVDAGRLHARVPIPEAEQFDRQILERVLDGLRSLKS
>NZ_CP006871.1|WP_016575341.1|3718237_3718666_+|roadblock/LC7-domain-containing-protein
MNSPTRRRVTEDKSWVLAPLLELPHVVHAAVISGDGFIEGASPGLSREAAEGVAAMMSALQGAGRAVTAAFTEQDDARLRQTVIESDEGFVFAIPAGENTCLAVFADPEVNMGVVAHHMQIQVTTLGKKVMNSPARDTGSHA
>NZ_CP006871.1|WP_020929294.1|3729076_3730015_-|GTPase-Era
MSVRTESTAPHRAGFACFVGRPNAGKSTLTNALVGTKVAITSNRPQTTRHTVRGIVHRPDAQLVLVDTPGLHKPRTLLGERLNDVVRTTWSEVDVIGFCLPADQKLGPGDRYIASELAEIKKTPKIAIVTKTDLVDSKALATQLLAIDRLGKELGIEWAEIIPVSAVGDQQVSLLADLLVPLLPEGPALYPEGDLTDEPEQVMVAELIREAALEGVRDELPHSIAVVVEEMLPREDRPADKPLLDIHANVYIERPSQKGIIIGPKGKRLKEVGTKSRKHIEALLGTPVFLDLHVKVAKDWQRDPKQLRKLGF
>NZ_CP006871.1|WP_037632337.1|3730120_3730483_-|hypothetical-protein
MTEAAPLDPEDRKIITLARSARARNGVPEGAAVRDETGRTYVAGTVALDSLQLSALQTAVAMAVASGATSLEAAAVVTDADQAADADRAAVRDLGGPDTPVLVAAPDGTLRAATPAGPAA
>NZ_CP006871.1|WP_016574970.1|3731269_3732589_-|HlyC/CorC-family-transporter
MTTLIAVAVLLVVVAWLAACAEAGLTRTTSFRAEEAVRSGRRGSAKLAAVAADPTRYLNVALLVRVGCEMAAGALVTYACLRSFDTTWEALTVAIAVMVLVSYVAVGVSPRTIGRQHPLNTATAAAYVLLPLARVMGPVPQLLILLGNALTPGKGFRKGPFASEAELRSLVDLAEKESLIEDEERRMVHSVFQLGDTLVREVMVPRTDLISVERFKTIRQALTLALRSGFSRIPVTGENEDDVVGVVYLKDLARKVHISRDAETDLVSTAMRPAVFVPDTKNAGDLLREMQRDRNHVAVVIDEYGGTAGIITIEDILEEIVGEITDEYDRELPPVQDLGGGRYRVTARLDIGALGELYGLAELDDEDVETVGGLLAKQLGRVPIAGATVEIDLSEHASDPDLKALRLIAEAPAGRRNKIVTVLCEPVRAAEAEGDGAGG
>NZ_CP006871.1|WP_016574969.1|3732600_3733098_-|rRNA-maturation-RNase-YbeY
MSIDVNNESGTDIDEQAILDVARYALARMRIHPLSELSVIVVDAEAMEQLHIQWMDLPGPTDVMSFPMDELRPPAKDDEEPPQGLLGDIVLCPEVAEQQGKAAPTGHTMDEELQLLTVHGVLHLLGYDHEEPDEKAEMFGLQAAIVDGWRAERGMTGPSPAPTVT
>NZ_CP006871.1|WP_020929295.1|3733137_3734139_-|PhoH-family-protein
MTQTPTRAQASAHFTVPAKHPMVTVLGSGDSLLRVIEDAFPATDIHVRGNEISAVGDAREVALVQRLFDEMMLVLRTGQPMTEDAVERSIAMLRAAENGEGASETPAEVLTQNILSNRGRTIRPKTLNQKRYVDAIDKHTIVFGIGPAGTGKTYLAMAKAVQALQAKQVNRIILTRPAVEAGERLGFLPGTLYEKIDPYLRPLYDALHDMLDPDSIPRLMAAGTIEVAPLAYMRGRTLNDAFIILDEAQNTNPEQMKMFLTRLGFESKIVITGDVTQIDLPGGTKSGLRQVRDILTDVDDVHFSELTSRDVVRHKLVGRIVDAYEKYDSRNGK
>NZ_CP006871.1|WP_016574967.1|3734323_3735520_-|carbohydrate-kinase
MNTGRRDVQPPAGPATEPPGLDPLAAVRRAGDPPTDVYLTGTVFLDIIFTGLDSAPVRGTESWARGMGSSPGGVANMATALARLGLRTSLAAAFGDDMYGEYCWEALERGEGIDLELSRTVPGWHSPVTVSMAYEGERTMVSHGHEAPAPEHAFDGGHAPGCPPPTRACVASLVPGRREGWLGCAAGRGSRIFADVGWDDTGRWDPADLADLEHCEAFLPNAEEAMRYTRTDCPRAAARKLADLVPLAVVTLGSEGACAVDARTGESAEVPAIVVEALDPTGAGDVFVAGFVTGTLADWPLADRLSFAGLSAALSVQEFGGSLSAPGWAEIAAWWRRVRACDTGATAGLRRQYGFLDAVLPAPGVSLGSTGAAGPARAAAAASPLARAVPTIGFRPPA
>NZ_CP006871.1|WP_016574966.1|3735587_3736928_+|6-phospho-beta-glucosidase
MRLSILGGGGFRVPLVYRALLDDPTRSVSELTLYDTDPRRVAVISDVLAELARGRTQPVPVRVAETLDAALTGADFVFSAIRVGGTAGRIRDERIPLSEGVLGQETVGAGGVLYGLRTIPVALHVAERVAALAPGAWVINFTNPAGMVTEAMAQVLGDRVIGICDSPVGLVRRAARAAGADPTALEDPARSGYDYVGLNHLGWLRSLTVDGTDVLPGLLGDVAALGSFEEGRLFGPEWLRVLGALPNEYLHYYYFRRETLHSVQDTAQTRGEFLDRQQGGFFDRAAAAGSPDAVYALWERTRLEREQTYMAHSREATGGWQRDSDDLEGGGYDRVALALMHAIAGDSGRRLILNVRNGTTVPQLAPDAIVETVCEVTAKGARPLPCAPLREDQLGLMLQIKAVERATVAAALFKDRDAALRALALHPLVDSAAVAARILQRAGTQG
>NZ_CP006871.1|WP_016573927.1|3737157_3737787_-|MBL-fold-metallo-hydrolase
MGARIDHLVTSGTFSLDGGTWDVDNNVWIVGDGSEAVVIDAAHDADAILRALDGRTLRAIICTHAHNDHIDAAPALAARTGARILLHPDDLPLWKQTHPDTAPDGDLSDGQVLTIAGIDLTVLHTPGHAPGAVCLHAPDLNTVFTGDTLFQGGPGATGRSFSDFPTIIDSIRDRLLTLPPTTVVRTGHGDQTTIEREAPHLAEWVARGH
>NZ_CP006871.1|WP_016573928.1|3737786_3738872_-|S-(hydroxymethyl)mycothiol-dehydrogenase
MAQEVRGVVAPGKNEAVRLETVLVPDPGPGEAVVQVQACGVCHTDLHYKQGGINDDFPFLLGHEASGVVESVGEGVTDVAPGDFVILNWRAVCGSCRACLRGRPQYCFNTHNARQKMTLKDGTELTPALGIGAFADKTLVAAGQCTKVDPEVAPAVAGLLGCGVMAGIGAAINTGQVGRGDTVAVIGCGGVGDAAVVGARLAGAAKIIAVDIDDRKLETARTMGATHTVNSRSTDPVEAVRELTGGFGADVVIDAVGRPETYRQAFYARDLAGTVVLVGVPTPEMTLELPLLDVFGRGGALKSSWYGDCLPSRDFPMLIDLHQQGRIDLGGFVTETIGIDEVERAFDRMHAGDVLRSVVVL
>NZ_CP006871.1|WP_016573929.1|3739055_3740363_-|mandelate-racemase
MVAHHPADLVVTEVRLTPVLVADPPLLNTQGVHQPYTPRLIIELVTAGGATGLGETYGDAEYLALARPLATVLVGRKVTDLNALAALTDPGDGAAGTAGPDGVDAAGLRGVRTADKLRRSVRSGFEVACLDAWGHATGLPVHALLGGAVRDRVPYSAYLFYRWERHPDGPGEPDDWGAALDPAGIVAQARRFADRYGFTSFKLKGGVLPPDREAAAIRALAAAFPGRPLRLDPNGAWSVRTALKVADELADVLEYLEDPVSGTEAMAEVAAGTTVPLATNMCVTTFEELPEAIARDAVRIVLSDHHYWGGLLATRELAALCRTFGLGLAMHSNTHLGISLAAMTHVAATVPDLDHACDTHYPWQTEDVLTERLAFRDGHLDVGDAPGLGVTLDRDRLAALHHRWLADDGTYRNRDDAAAMRRVHPDWTTPPVPRW

Crispr_ID: NZ_CP006871_4

• CRISPR_ID: NZ_CP006871_4
• CRISPR_location: 3765517-3765596
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP006871_4

Consensus_repeat	Method
GCGACAGCGCCTCCCCTCCCCCCG	CRISPRCasFinder

spacers of NZ_CP006871_4

>4.1|3765541|32|NZ_CP006871|CRISPRCasFinder
GATCCGGGTGGACGGAACCACCCCCCGCCATT

CRISPR arrays and Neighbor proteins around NZ_CP006871_4

CRISPR arrays

The CRISPR arrays of NZ_CP006871_4

>merge|NZ_CP006871|4|3765517-3765596|CRISPRCasFinder
GCGACAGCGCCTCCCCTCCCCCCGGATCCGGGTGGACGGAACCACCCCCCGCCATTGCGACAGCGCCTCCCCTCGCCCCG

>NZ_CP006871|4|4|3765517-3765596|CRISPRCasFinder
GCGACAGCGCCTCCCCTCCCCCCG	GATCCGGGTGGACGGAACCACCCCCCGCCATT
GCGACAGCGCCTCCCCTCGCCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_045788036.1|3780079_3782104_-|membrane-protein	unknown	unknown	gnl|CDD|224235
NZ_CP006871.1|WP_016571903.1|3754607_3756497_-|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|223953
NZ_CP006871.1|WP_016573215.1|3768943_3769708_-|hypothetical-protein	unknown	unknown	gnl|CDD|376562
NZ_CP006871.1|WP_016573211.1|3777376_3777610_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016573216.1|3767807_3768653_-|DegV-family-protein	unknown	unknown	gnl|CDD|273257
NZ_CP006871.1|WP_016577213.1|3750951_3752184_-|coproporphyrinogen-III-oxidase	unknown	unknown	gnl|CDD|180172
NZ_CP006871.1|WP_037635120.1|3778791_3779445_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP006871.1|WP_020929299.1|3752294_3754412_-|hypothetical-protein	unknown	unknown	gnl|CDD|369272
NZ_CP006871.1|WP_016577822.1|3779441_3779876_-|ribosome-silencing-factor	unknown	unknown	gnl|CDD|376779
NZ_CP006871.1|WP_037635116.1|3769984_3772882_-|leucine--tRNA-ligase	unknown	unknown	gnl|CDD|234743
NZ_CP006871.1|WP_016571904.1|3756812_3758687_-|elongation-factor-4	unknown	unknown	gnl|CDD|235462
NZ_CP006871.1|WP_106966096.1|3760013_3760628_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016573213.1|3773203_3775162_-|serine-protease	unknown	unknown	gnl|CDD|173788
NZ_CP006871.1|WP_016577677.1|3761934_3762189_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016577676.1|3760836_3761820_-|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl|CDD|236130
NZ_CP006871.1|WP_078487405.1|3750630_3750915_+|DUF1876-domain-containing-protein	unknown	unknown	gnl|CDD|378103
NZ_CP006871.1|WP_079164315.1|3766265_3767453_-|ComEA-family-DNA-binding-protein	unknown	unknown	gnl|CDD|224472
NZ_CP006871.1|WP_016576187.1|3759098_3759365_+|30S-ribosomal-protein-S20	unknown	unknown	gnl|CDD|376586
NZ_CP006871.1|WP_016573094.1|3762304_3763078_-|arylamine-N-acetyltransferase	unknown	unknown	gnl|CDD|366312
NZ_CP006871.1|WP_037635115.1|3782128_3782740_-|nicotinate-nucleotide-adenylyltransferase	unknown	unknown	gnl|CDD|234611

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_016571903.1|3754607_3756497_-|long-chain-fatty-acid--CoA-ligase	gnl|CDD|223953	COG1022, FAA1, Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism].	0
NZ_CP006871.1|WP_016573215.1|3768943_3769708_-|hypothetical-protein	gnl|CDD|376562	pfam01544, CorA, CorA-like Mg2+ transporter protein. The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli. CorA is virtually ubiquitous in the Bacteria and Archaea. There are also eukaryotic relatives of this protein. The family includes the MRS2 protein from yeast that is thought to be an RNA splicing protein. However its membership of this family suggests that its effect on splicing is due to altered magnesium levels in the cell.	0.00736248
NZ_CP006871.1|WP_045788036.1|3780079_3782104_-|membrane-protein	gnl|CDD|224235	COG1316, LytR, Transcriptional regulator [Transcription].	3.85357e-12
NZ_CP006871.1|WP_016577213.1|3750951_3752184_-|coproporphyrinogen-III-oxidase	gnl|CDD|180172	PRK05628, PRK05628, coproporphyrinogen III oxidase; Validated.	0
NZ_CP006871.1|WP_037635120.1|3778791_3779445_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.06359e-59
NZ_CP006871.1|WP_016573216.1|3767807_3768653_-|DegV-family-protein	gnl|CDD|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	6.18195e-103
NZ_CP006871.1|WP_016577822.1|3779441_3779876_-|ribosome-silencing-factor	gnl|CDD|376779	pfam02410, RsfS, Ribosomal silencing factor during starvation. This family is expressed by almost all bacterial and eukaryotic genomes but not by archaea. Its function is to down-regulate protein synthesis under conditions of nutrient shortage, and it does this by binding to protein L14 of the large ribosomal subunit, thus acting as a ribosomal silencing factor (RsfS) by blocking the joining of the ribosomal subunits. This family is structurally homologous to nucleotidyltransferases.	2.86003e-40
NZ_CP006871.1|WP_037635116.1|3769984_3772882_-|leucine--tRNA-ligase	gnl|CDD|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP006871.1|WP_020929299.1|3752294_3754412_-|hypothetical-protein	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	1.60366e-41
NZ_CP006871.1|WP_016573213.1|3773203_3775162_-|serine-protease	gnl|CDD|173788	cd04056, Peptidases_S53, Peptidase domain in the S53 family. Members of the peptidases S53 (sedolisin) family include endopeptidases and exopeptidases sedolisin, kumamolysin, and (PSCP) Pepstatin-insensitive Carboxyl Proteinase. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of Asn in subtilisin. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values. Characterized sedolisins include Kumamolisin, an extracellular calcium-dependent thermostable endopeptidase from Bacillus. The enzyme is synthesized with a 188 amino acid N-terminal preprotein region which is cleaved after the extraction into the extracellular space with low pH. One kumamolysin paralog, kumamolisin-As, is believed to be a collagenase. TPP1 is a serine protease that functions as a tripeptidyl exopeptidase as well as an endopeptidase. Less is known about PSCP from Pseudomonas which is thought to be an aspartic proteinase.	1.00082e-74
NZ_CP006871.1|WP_016577676.1|3760836_3761820_-|DNA-polymerase-III-subunit-delta	gnl|CDD|236130	PRK07914, PRK07914, hypothetical protein; Reviewed.	1.1006e-85
NZ_CP006871.1|WP_016573094.1|3762304_3763078_-|arylamine-N-acetyltransferase	gnl|CDD|366312	pfam00797, Acetyltransf_2, N-acetyltransferase. Arylamine N-acetyltransferase (NAT) is a cytosolic enzyme of approximately 30kDa. It facilitates the transfer of an acetyl group from Acetyl Coenzyme A on to a wide range of arylamine, N-hydroxyarylamines and hydrazines. Acetylation of these compounds generally results in inactivation. NAT is found in many species from Mycobacteria (M. tuberculosis, M. smegmatis etc) to man. It was the first enzyme to be observed to have polymorphic activity amongst human individuals. NAT is responsible for the inactivation of Isoniazid (a drug used to treat Tuberculosis) in humans. The NAT protein has also been shown to be involved in the breakdown of folic acid.	7.02715e-81
NZ_CP006871.1|WP_079164315.1|3766265_3767453_-|ComEA-family-DNA-binding-protein	gnl|CDD|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	2.67567e-19
NZ_CP006871.1|WP_016576187.1|3759098_3759365_+|30S-ribosomal-protein-S20	gnl|CDD|376586	pfam01649, Ribosomal_S20p, Ribosomal protein S20. Bacterial ribosomal protein S20 interacts with 16S rRNA.	2.66446e-22
NZ_CP006871.1|WP_016571904.1|3756812_3758687_-|elongation-factor-4	gnl|CDD|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP006871.1|WP_037635115.1|3782128_3782740_-|nicotinate-nucleotide-adenylyltransferase	gnl|CDD|234611	PRK00071, nadD, nicotinate-nucleotide adenylyltransferase.	3.35896e-101
NZ_CP006871.1|WP_078487405.1|3750630_3750915_+|DUF1876-domain-containing-protein	gnl|CDD|378103	pfam08962, DUF1876, Domain of unknown function (DUF1876). This domain is found in a set of hypothetical bacterial proteins.	2.2388e-31

Protein sequences

>NZ_CP006871.1|WP_016573094.1|3762304_3763078_-|arylamine-N-acetyltransferase
MDEVTADAYLRRIAADRPAVPDADALRALQLSHLRAVPFENLAIHLGEEIVLAERPLLDKIVGARRGGFCYELNGAFAMLLGTLGYEVELLSARVFGPEGLGIPYDHLALRVHTPTGPWLTDVGFGRNSHRPLRLDSVADQHDPAGVFRIARTPEGDLDVHRNGEPQYRLEQRPRELADFEVGCWWQSTSPRSHFRQSLVCSQLTETGRVTLSGRTLVITGADGAREERELAADEVVPAYRTHFGITLDREPVLLGG
>NZ_CP006871.1|WP_016577677.1|3761934_3762189_+|hypothetical-protein
MNDTHHSRHVLVLPDRDAAEEVAEALTERFGVAEEPQLVRDALAGEDDAEDAQWLVVVEDPDAAYDAARLDALAGEYEGWRETE
>NZ_CP006871.1|WP_016577676.1|3760836_3761820_-|DNA-polymerase-III-subunit-delta
MARKTANDDPLAPVTIAVGQEELLLDRAMQQVVAAARAADADTDVRDLTPDHLQPGTLAELTSPSLFAERKVVVVRASQDLSADTIKDVKAYLGSPAEEITLVLLHAGGAKGKGLLDAARKAGAREVACPKMTKPADRLAFVRGEFRATGRSATPEACQALVDAIGSDLRELASACAQLAADVEGTIDDAVVARYYTGRAEASSFTVADRAVEGRAAEALEALRWAIATGVAPVMITSALAQGVRAIGKLASAPRGARPGDLARDLGMPPWKIDRVRQQMRGWSADGVAVALRAVAEADAGVKGGGDDPEYALEKAVVTIARAARSR
>NZ_CP006871.1|WP_106966096.1|3760013_3760628_+|hypothetical-protein
MFATGAFSSEPHPVLKGYAFRDDLCSVTSLMPFENAHYKTKPSAGTGSTGSSGPSSPPNPQHSGSRMGSMDSMWCNVSLTPEGAGTTDYSSSWVYSAATLHKKTDPAPEFADLYRAYETQQTSTTYKVEPVPGIGDEAFLVTRNDSGALNSSYVILAVRDGWMTYQTTWSSYTTSSSTVKPPGPAEIATMLESSARETLSRLHD
>NZ_CP006871.1|WP_016576187.1|3759098_3759365_+|30S-ribosomal-protein-S20
MANIKSQMKRIKTNEKARQRNKAVKSSLKTAIRRTREAIEAGDLQKATAAQALAAQKLDKAVSKGVLHKNNAANKKSALAKKVASLKG
>NZ_CP006871.1|WP_016571904.1|3756812_3758687_-|elongation-factor-4
MPATPTNVPEPSRTDPALLRNFCIIAHIDHGKSTLADRMLQLTGVVDQRQMRAQYLDRMDIERERGITIKSQAVRLPWSPSEGEEGSGTTHILNMIDTPGHVDFTYEVSRSLAACEGCILLVDAAQGIEAQTLANLYLAMENDLTIIPVLNKIDLPAAQPEKFAAELANLVGCEPEDVLKVSAKTGVGVPELLDKVVREVPAPVGVKDAPARAMIFDSVYDAYRGVVTYVKVVDGTLSKRERIKMMSTGAAHELLEIGTNSPEMTPADGLSVGEVGYLITGVKDVRQSKVGDTITQLSKGAQEPLGGYKDPKPMVFSGLYPLDGSDYPELRDALDKLQLNDAALVYEPETSAALGFGFRVGFLGLLHLEVIRERLEREFDLDLIATAPNVVYRVEMEDGVEHTVTNPSEFPTGKIDVVHEPVVRATILAPSEFIGAIMELCQTRRGALLGMDYLSEDRVEIRYTLPLAEVVFDFFDQLKSKTRGYASLDYEPTGEQTSDLVKVDILLHGDKVDAFSAITHKDKAYAYGVRLVGKLRELIPRQNFEVPIQAAIGSRVIARETVRAIRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKMVGSVEVPQDAFIAVLSSDSDGDSKAKK
>NZ_CP006871.1|WP_016571903.1|3754607_3756497_-|long-chain-fatty-acid--CoA-ligase
MTDTHTLIDNRPPSVATLFLERVAATPDVEAYRYPVPPAAGSGPDDWKTLTWSDAAERVLAAAAGLIALGVRPEERVALAANTRVEWILADLGVLCSGAATTTVYPSTNVDETAFILADSGSRVLIAEDAAQLAKAREKRAELPELSHVVVIDETAARPADDDPDDWVLSLAELEKRGTAYLEQHPECVKERVAALRADQLATLIYTSGTTGRPKGVRLPHDCWSYMARAIQATGMVTADDVQYLWLPLAHVFGKVLTAGQISVGHVIAVDGRVDKIIENLPVVRPTYMAAVPRIFEKVYNGVAAKAREGGGAKYKVFQWAAGVAREYAKASQDNFRRTGNASVPFALAAKHKVADALVYTKLREAFGGRLRAAISGSAALAPEIGYFFAGAGIHILEGYGLTESSAASFVNPGEAYRTGTVGKPLPGTEVRIAEDGEILLRGPGIMQGYHGLPDKTAEVLEEDGWFHTGDIGELSPDGYLRITDRKKDLIKTSGGKYIAPAEVEGQFKAVCPFVSNVIVHGANRNFCTALIALDEPTILKWAEEHGLGGKGYAEVVATDQVRALIDGYVERVNGELQRWQQIRKFRLLPRDLDIEHGEITPSLKIKRPVVERAFKDLLDEMYAGAREA
>NZ_CP006871.1|WP_020929299.1|3752294_3754412_-|hypothetical-protein
MTTSAGRNDVAGAAARSLRATLPGDPRAAAAARRFVRTAFADWTERRLPGADRLTDRLADEAVLLVSELVTNAVVHAGTTVELLCRLDPAEEHVPYPDDPPDAVPEEPPRPGLVVEVSDRHPTRPVRAGEDTGAPEGGGHGLRLISAVADAWGVTYRRAMKTVWFRLPVGAPDATWPEPETTDGAYGSYGSYDGYGTHDGYGAYDGPDAYAGHGARAAYDTFDDQRFRRELRASELLAPVPRRPAPPEDRPERDRGGVDSGALSFLAEASDLLSGQLDADQVASLACQLIVPRLADWCAVWLHDGDGGAPGRGLAEDGQAPRLARVWHLAEGRIDSLRTALEKEPPSRWTDGATDNRPVPVPWPWPPEPTGPEPGGAALACPLVAGGRRLGTLLLGRAGLRRFPGEVVALTEDLCGRAARAVATARAYSRQERISRVLQRRLLPQGRARVPGVASAVVYEPREGAWAGGDFWDLFDAGDGRWCFALGDVCGSGPEAAAVTGLARPVLRLLARDGFGVAEVLDRLNKTMAREAADSVAAVAAAVAAAGAGAEAPVEIREEGEQARFLSLLYGEIVPYRGGAGGARCTLASAGHPLPLVLGADGAVRVAAAPQMLLGVVEDAAYVSESFDLCPGETLVCVTDGVTERRCGRRLFDDEDGLASALAGAAGRSADAIAEHIRRTVHAFGPTPPDDDLALMVLQAAGCGG
>NZ_CP006871.1|WP_016577213.1|3750951_3752184_-|coproporphyrinogen-III-oxidase
MPSALPDGEPMPQDGALPRHALTGAAERPLGFYLHVPYCATRCGYCDFNTYTASELRGPGGALASRENYADTLVEEVRLARKVLGDDPRPVETVFVGGGTPTLLPAADLGRMLAALRDEFGLAPDAEITTEANPESVDPRYLAELRAAGFNRVSFGMQSARQHVLKVLDRTHTPGRPEACVAEARAAGFAHVNLDLIYGTPGESDDDWRASLEAATAAGPDHVSAYALIVEEGTQLARRIRRGEVPMTDDDVHADRYLIAEEHLTAAGFSWYEVSNWATTEAARCRHNELYWTGADWWGAGPGAHSHVGGVRWWNVKHPAAYAQALAEGRSPGAGRELLADEDRRVERILLELRLADGCPLDLLAPAGARAAARAVADGLLAPGPYEAGRAVLTLRGRLLADAVVRDLVD
>NZ_CP006871.1|WP_078487405.1|3750630_3750915_+|DUF1876-domain-containing-protein
MTAMLKTAVGWHVELEFEEDTHRTRAAALVRLPDGTEVRSHGYASRHPADGNQPRVGEEVAGARALNDLAMQLLTKAHGEIDSASGRTSFPLSH
>NZ_CP006871.1|WP_079164315.1|3766265_3767453_-|ComEA-family-DNA-binding-protein
MTSAAPFARWGKRERERARQWKRERMRARAAVIFGAGLEAGGRDGDEEGASGAGRDDPSGQDPGGGSGRPAQGDRADRPGAGEGEGEGPAPGAIGEGSRGRGAARDPHGPSGGPDPFDTRGEPSHAHRAPPRREHDPPAVRRVERWRSAVRERLPLWLQLRCGTDSKALAALALVLVVAVGFAVQHFWAATPERVSAPGAERPIAAPGPGARPPGPTWASADTSPRGPTTGGPPGGAVRMVVVDVAGKVRHPGIHRLPAGSRVTDALTAAGGALRGTELRGLNQARLLTDGEQILVGEPGAGTTGGVSGGGPTGGGGAGGGAGSGGPPGLASGPVSLSTATEQQLDALPGVGPVLARHIVEFRTQHGGFTSVDQLRQVTGIGARRLADLRPLVTP
>NZ_CP006871.1|WP_016573216.1|3767807_3768653_-|DegV-family-protein
MSRHVAIVTDSTAYLPRTAVERHRITAVPLTVVLGDQALEEGTEISARSVAQALQKRRPVTTSRPSPAVFADTYRTLAAAGAAGIVSLHLSSEFSGTYDAAVLAAKDAPVPVRVVDTGMVAMALGFCALAAADVVDAGGDVDDAVAAAEKRAAGTSTYFYVDTLDYLRRGGRIGAAQALLGSALAVKPILQLADGRIELLEKVRTASKAIARLEEIAAERAGEGQVDIAVHHLAAAERAEALAQRLRERVPGLNELLVSEVGAVIGAHTGPGLLGAVVSPR
>NZ_CP006871.1|WP_016573215.1|3768943_3769708_-|hypothetical-protein
MEAAVAIFGLLFVLFVVAGVFVAVKAAQAAKRGVDRKVAQARRTVEDTTLRARQFTQPGVVGELAQLRLSLRTSMRATQEILRDASPDDASLVEAGRLFERLSVHGRELDDDLRRLEREPNRATLADRLPELRERLARITHSAESLRWAARDRARKFADDDLAALSDQIDVEAGALRHWTDDAPGGERERGTAGGASGADAGPTGGGAYSWGAVEDEAPAIPARDPRTRPTYPWEKTPQPEPSRRAEGSGGVAG
>NZ_CP006871.1|WP_037635116.1|3769984_3772882_-|leucine--tRNA-ligase
MSETTNAAEVAAPHRYTAALAADIEARWQDFWEAEGTYEAPNPKGDLGGDAELVARPKKFIMDMFPYPSGAGLHVGHPLGFIATDVYARYHRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANIVNMRRQLRRLGLGHDQRRSVETIDPAYYKWTQWIFLQIFNSWYDPEADSARPIDTLVAQFEAGTRPTPDGRPWAELSGIERANVLGEYRLAYASDAPVNWCPGLGTVLANEEVTAEGRSERGNYPVFKAKLRQWNMRITAYADRLLRDLDALDWPEAIKLQQRNWIGRSEGARVDFPVGDTDKITVFTTRQDTLFGATYMVLAPEHPLIAGADNGGGSIVPDAWPEGTHEVWTGGHATPAEAVAAYRKQAAAKSDVERQAEAKDKTGVFTGVYATNPVSGEQVPVFIADYVLMGYGTGAIMAVPAHDVRDFAFARAFELPVRCVVEPTDGRGTDAATWDDAFASYDAKLVNSAGAAISLDGLGVTEAKAKITEWLSANGIGAGTVNYRLRDWLFSRQRYWGEPFPIVYDEDGVAHSLPESMLPLELPEVDDYSPRTFDADDADTQPETPLSRNEDWVNVELDLGDGRGVQRYRRETNTMPNWAGSCWYEMRYLDPNNDDALVDPAVEQYWMGPRDGQPHGGVDLYVGGAEHAVLHLLYARFWSKVLHDLGHVSSVEPFHKLYNQGMIQAYVYRDARGIAVPAAEVEEHDGGVFYYEGGKVSRLLGKMGKSLKNAVTPDEICAEYGADTLRLYEMAMGPLDVSRPWDTRAVVGQYRLLQRLWRNVVDEATGEVTVVDAEPDEATLRALHKAIDGVTQDMANLRFNTAIAKITELNNHLTKVGGPVSRTVAEQLVLLVAPLAPHIAEELWRKLGHADSVVHADFPVADPAYVVDETVTCVVQIKGKVKARLEVAPTISDADLEAAALAEPAVVAALDGAGIRKVIVRAPKLVNIVPA
>NZ_CP006871.1|WP_016573213.1|3773203_3775162_-|serine-protease
MRASRTRSPRVRVGLAWAAALPLVAGALALGAPAADAAGHDGGRHALQGTKPRWATDQADQGATSGATAVNARVYLAGRDAKGLADYAKAVSDPHSALYGKYLRPAQVQARYGATPDQIARVTAWLKKSGLTVTGTTDRYVTVTGDAAAAERAFATDLHNYRKNGHTYHAPSATASAPSTVSDAVLTVTGLDNAPRMARHHSTELPPPSAVFRNSGPFSTYYGSRTNQNLPSAYGGKAPYAIKGYTGKQLRAAYGAKGWTGKGVTVAITDAYASPTIAKDADTYAGRNGDPRYRKGQLSQVLPKDYTHIKECGAAGWYGEETLDVEAVHAVAPGADIVYVGAASCNDDDLLDSLGKVVDGRLADIVSNSWGDIEANETPDTAAAYDQLFQRGAVEGIGFYFSSGDNGDEVANTGTKQVDTPANSAWVTAVGGTSLAVGKGNSYQWETGWGTQKAVLSKDGNDWTDFPGAFNGGAGGGTSKTVAQPFYQRGVVPDALAKANGGGAMRTVPDIAAVADPNTGFLVGQTQTLPDGKLGYEEYRIGGTSLAAPVIAGVQALAQQARHGIAIGFANPAIYQRYGTSALHDVTDHPLGAGRDLAVVRVDFANGIDASKGTITSLRSLGKDSSLHATVGYDDVTGVGTPGAGYVSSYRP
>NZ_CP006871.1|WP_016573211.1|3777376_3777610_-|hypothetical-protein
MGAHSRKCDWCGSGTPIVRDMEPVNADYQYWCEECARALVIKGDPIETYRELEGEPIYGRLLEEHCTLKRFYSFATA
>NZ_CP006871.1|WP_037635120.1|3778791_3779445_-|histidine-phosphatase-family-protein
MNGTKGGRGRRVVLWRHGQTSWNLERRFQGSTDIELTETGVAQARRAARLLAALQPDAIVASDLRRAAATAGELAALTRLEVSHDAALRETYAGAWQGLTHEEILAQYGEQYSAWKRGEPVRRGGGELETEVADRAAPVVLHHADKLPDDGTLVVVSHGGTIRTTIGRLLGLEAHHWEGLGGLSNCCWSVLGEGARGWRLLEHNAGTLPEPVLGDDD
>NZ_CP006871.1|WP_016577822.1|3779441_3779876_-|ribosome-silencing-factor
MTATDRSLELINAAALAAADKLAHDIIAYDVSDVLSITDAFLLASAPSDRQVKAIVDEIEERLNKDLGAKPVRREGDREARWVLLDYVDIVVHVQHSEERVFYALERLWKDCPEIDLPEEAKATRGKAAEHSRATAVDEDGDLR
>NZ_CP006871.1|WP_045788036.1|3780079_3782104_-|membrane-protein
MSDRHDPYGPQDPHPQDPYAPQQGQHGQQGQGYTYDAYGRPVSHEAPQQYEAQQQYGQQPHDPYGQPAGPGAQPGYDPYDPYGTQGGQGPPAHQPYQGQPEYGYDGYGGQQVQQQPGYPQQYDPYAQPPQAPPQQSPQQADWIPQQAQQPPYEQFSYGEQQPHPGQEPHEPPQYARAPPQQSPQQADWIPQQAQQPPYEQFSYGEQQPHPGQEPHEQPQYARAPQGQAGSAPAAAPVEPPAPAGPKGAAAPGGGPDAEDYHTEQFSFVEEPDDDSEDVIDWLKFTESRTERREEAKRRGRSRLIALSVVLALLVVGGVGYLWWAGKLPGLAGAGGGAAAEASGQKRDVLVVNLRDTKTGNTSTALLVDNETTHKGTTLLLPNSLIVTKDDGTTTTLGKSVKDDGTDATREALNTLLGADLNASWRLDTPYLENLVETVGGITVDTDAAVPGAKKGDSPVVKQGTGQLLNGQAAVAYATYQGPGDTQAKQLARFGQVMQATLAKVSSDADGATATVKSLLQILDPPLTEAQLGSSLAQRAELAKTGKYSTEALPVQADGTISQSTAAGVVKDVLGGTVKKTSPGVTPRVAVRNASGNQAATGKAQVALLNGGYTFVDGGSGSTAATSQVTYADAPQRAKATEVAKTLGLPAGAVQQGKVAANADIVVVLGQDYKG
>NZ_CP006871.1|WP_037635115.1|3782128_3782740_-|nicotinate-nucleotide-adenylyltransferase
MGEHTGPVKRRLGVMGGTFDPIHHGHLVAASEVASQFHLDEVVFVPTGHPWQKSHKTVSPAEDRYLMTVIATASNPQFSVSRIDIDRGGKTYTIDTLRDLRAEHCDADLFFITGADALSQILTWHDAAELVSLAHFIGVTRPGHVLADPGLPEGAVSLVEVPALAISSTDCRARVAQGDPVWYLVPDGVVRYIDKKQLYRDDR

Crispr_ID: NZ_CP006871_5

• CRISPR_ID: NZ_CP006871_5
• CRISPR_location: 4827969-4828398
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 9 spacers

Consensus repeat of NZ_CP006871_5

Consensus_repeat	Method
GCGNTCGTCACGACGGTC	CRT

spacers of NZ_CP006871_5

>5.1|4827987|27|NZ_CP006871|CRT
GTCACGGCGGTCGAAGGAACGACCACC
>5.2|4828032|27|NZ_CP006871|CRT
GTCGCGACGGTCGAAGGAACGACCACC
>5.3|4828077|27|NZ_CP006871|CRT
CCGGTCACGGTCCCGACCGAAGCCACC
>5.4|4828122|27|NZ_CP006871|CRT
GTCACGACGGTCGAAGGAACGACCACC
>5.5|4828167|51|NZ_CP006871|CRT
CCGGCGCTCGAAGTTGCCGCGCTCGTCACGACGGTCACGACCGAAGCCGCC
>5.6|4828236|27|NZ_CP006871|CRT
GTCACGACGGTCGAAGGAACGACCGCT
>5.7|4828281|18|NZ_CP006871|CRT
CCGGCGCTCGAAGTTGCC
>5.8|4828317|27|NZ_CP006871|CRT
ACGACCGGCGCCACCGCGGTCGTCCCG
>5.9|4828362|19|NZ_CP006871|CRT
GCTCGGCCCGGCCTGCGCC

CRISPR arrays and Neighbor proteins around NZ_CP006871_5

CRISPR arrays

The CRISPR arrays of NZ_CP006871_5

>merge|NZ_CP006871|5|4827969-4828398|CRT
GCGGTCGTCACGACGGTCGTCACGGCGGTCGAAGGAACGACCACCACGGTCGTCACGACGGTCGTCGCGACGGTCGAAGGAACGACCACCACGGTCGTCACGACGGTCCCGGTCACGGTCCCGACCGAAGCCACCGCGCTCGTCACGACGGTCGTCACGACGGTCGAAGGAACGACCACCGCGGTCGTCACGACGGTCCCGGCGCTCGAAGTTGCCGCGCTCGTCACGACGGTCACGACCGAAGCCGCCCCGCTCGTCACGACGGTCGTCACGACGGTCGAAGGAACGACCGCTGCGGTCGTCACGACGGTCCCGGCGCTCGAAGTTGCCGCGCTCGTCACGACGGTCACGACCGGCGCCACCGCGGTCGTCCCGGCGCTCGGGGCGACGGTCGCTCGGCCCGGCCTGCGCCGGCACGGTGGCCTCGGTC

>NZ_CP006871|5|1|4827969-4828398|CRT
GCGGTCGTCACGACGGTC	GTCACGGCGGTCGAAGGAACGACCACC
ACGGTCGTCACGACGGTC	GTCGCGACGGTCGAAGGAACGACCACC
ACGGTCGTCACGACGGTC	CCGGTCACGGTCCCGACCGAAGCCACC
GCGCTCGTCACGACGGTC	GTCACGACGGTCGAAGGAACGACCACC
GCGGTCGTCACGACGGTC	CCGGCGCTCGAAGTTGCCGCGCTCGTCACGACGGTCACGACCGAAGCCGCC
CCGCTCGTCACGACGGTC	GTCACGACGGTCGAAGGAACGACCGCT
GCGGTCGTCACGACGGTC	CCGGCGCTCGAAGTTGCC
GCGCTCGTCACGACGGTC	ACGACCGGCGCCACCGCGGTCGTCCCG
GCGCTCGGGGCGACGGTC	GCTCGGCCCGGCCTGCGCC
GGCACGGTGGCCTCGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_016573658.1|4821465_4822431_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381307
NZ_CP006871.1|WP_045788070.1|4830196_4830745_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_CP006871.1|WP_016578803.1|4817299_4818547_+|L-2-hydroxyglutarate-oxidase	unknown	unknown	gnl|CDD|183292
NZ_CP006871.1|WP_016575268.1|4840739_4841576_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016578497.1|4830965_4831316_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240572
NZ_CP006871.1|WP_020929262.1|4834864_4838860_+|ATP-dependent-RNA-helicase-HrpA	unknown	unknown	gnl|CDD|182986
NZ_CP006871.1|WP_016571945.1|4815577_4817026_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_078487424.1|4841766_4842885_+|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl|CDD|223411
NZ_CP006871.1|WP_016575269.1|4839263_4839500_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_026247493.1|4821035_4821338_+|hypothetical-protein	unknown	unknown	gnl|CDD|240242
NZ_CP006871.1|WP_016572879.1|4824543_4825698_+|DUF2332-domain-containing-protein	unknown	unknown	gnl|CDD|378386
NZ_CP006871.1|WP_037632267.1|4833557_4834637_-|membrane-protein	unknown	unknown	gnl|CDD|274414
NZ_CP006871.1|WP_020929266.1|4822538_4823963_-|hypothetical-protein	unknown	unknown	gnl|CDD|366703
NZ_CP006871.1|WP_016578805.1|4819667_4820951_+|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|379143
NZ_CP006871.1|WP_016575266.1|4843195_4843444_+|DUF3073-domain-containing-protein	unknown	unknown	gnl|CDD|378620
NZ_CP006871.1|WP_016571944.1|4812800_4814873_-|asparagine-synthase	unknown	unknown	gnl|CDD|366273
NZ_CP006871.1|WP_016578804.1|4818721_4819579_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl|CDD|234649
NZ_CP006871.1|WP_106966098.1|4831612_4833046_+|metallophosphoesterase	unknown	unknown	gnl|CDD|365906
NZ_CP006871.1|WP_003980577.1|4840030_4840237_-|developmental-transcriptional-regulator-BldC	unknown	unknown	gnl|CDD|133390
NZ_CP006871.1|WP_016572878.1|4825732_4826872_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_016573658.1|4821465_4822431_-|aldo/keto-reductase	gnl|CDD|381307	cd19081, AKR_AKR9C1, AKR9C family of aldo-keto reductase (AKR). Haloferax volcanii aldo-keto reductase is a founding member of aldo-keto reductase family 9 member C1 (AKR9C1).	3.4081e-158
NZ_CP006871.1|WP_045788070.1|4830196_4830745_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	6.02897e-06
NZ_CP006871.1|WP_016578803.1|4817299_4818547_+|L-2-hydroxyglutarate-oxidase	gnl|CDD|183292	PRK11728, PRK11728, L-2-hydroxyglutarate oxidase.	0
NZ_CP006871.1|WP_016578497.1|4830965_4831316_-|metallopeptidase-family-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	1.37911e-46
NZ_CP006871.1|WP_020929262.1|4834864_4838860_+|ATP-dependent-RNA-helicase-HrpA	gnl|CDD|182986	PRK11131, PRK11131, ATP-dependent RNA helicase HrpA; Provisional.	0
NZ_CP006871.1|WP_078487424.1|4841766_4842885_+|Glu/Leu/Phe/Val-dehydrogenase	gnl|CDD|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	6.47349e-87
NZ_CP006871.1|WP_026247493.1|4821035_4821338_+|hypothetical-protein	gnl|CDD|240242	PTZ00046, PTZ00046, rifin; Provisional.	2.43641e-05
NZ_CP006871.1|WP_016572879.1|4824543_4825698_+|DUF2332-domain-containing-protein	gnl|CDD|378386	pfam10094, DUF2332, Uncharacterized protein conserved in bacteria (DUF2332). Members of this family of hypothetical bacterial proteins have no known function.	5.08108e-75
NZ_CP006871.1|WP_037632267.1|4833557_4834637_-|membrane-protein	gnl|CDD|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	0.000339984
NZ_CP006871.1|WP_020929266.1|4822538_4823963_-|hypothetical-protein	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	2.13459e-26
NZ_CP006871.1|WP_016578805.1|4819667_4820951_+|PrsW-family-intramembrane-metalloprotease	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	2.69682e-48
NZ_CP006871.1|WP_016575266.1|4843195_4843444_+|DUF3073-domain-containing-protein	gnl|CDD|378620	pfam11273, DUF3073, Protein of unknown function (DUF3073). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.33987e-19
NZ_CP006871.1|WP_016571944.1|4812800_4814873_-|asparagine-synthase	gnl|CDD|366273	pfam00733, Asn_synthase, Asparagine synthase. This family is always found associated with pfam00310. Members of this family catalyze the conversion of aspartate to asparagine.	0.00317189
NZ_CP006871.1|WP_016578804.1|4818721_4819579_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl|CDD|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.09772e-91
NZ_CP006871.1|WP_106966098.1|4831612_4833046_+|metallophosphoesterase	gnl|CDD|365906	pfam00149, Metallophos, Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD or yeast MRE11. The most conserved regions in this superfamily centre around the metal chelating residues.	2.70538e-11
NZ_CP006871.1|WP_003980577.1|4840030_4840237_-|developmental-transcriptional-regulator-BldC	gnl|CDD|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	3.29995e-14
NZ_CP006871.1|WP_016572878.1|4825732_4826872_-|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	2.58842e-40

Protein sequences

>NZ_CP006871.1|WP_016572878.1|4825732_4826872_-|serine/threonine-protein-phosphatase
MVRGGGNRTGDEERRARRNQMSSWGRPLARWLPAVLIGGGVLFDLVTPPQYTAAPFLSAAPLVAAPLYSLRATSGTALAAVVTEVLLATYHGVEDYYQSATEAITVVVVALMALGINRVVRRSDARLASVRDVSEAAQRAVLPAPPDTLAGLAVAARYVGARAGARIGGDLHAIQDTPHGVRMIVGDVRGKGLEAVEAAVVVVGAFREAAEQETTLEAVASRLERAIEREGGRRAGLDQDEGFTTAVLAEVPAGNQSVLRILNRGHPSPLLLTPDGGLRELPPSTAALPLGLGDVAGWPDRADETFFPAGALLLLFTDGVTEARDRAGRFYDPCARLRGSQFSGPGDLLDVVVEDVARHTGGGPADDMALLAVQRPLEA
>NZ_CP006871.1|WP_016572879.1|4824543_4825698_+|DUF2332-domain-containing-protein
MVVNVANTGSTGNAGNAGNAGSTVNTPRDVAVRYREFSWHEARGRSDAHEELSARIGQDDEICELLARSLPSGNKQQPNLLLAAVRYLDGPHAESGPRGEAAYGRWREWTVRHWDEVRAVIMRRATQTNEPARCAALLPLLARLPQPLALLEVGTSAGLCLHPDRYRYRYVPDGPPSPHGEPVEAGAPDSAVTFTCRTSGVAPWDDGATVPPGARPEVVWRGGIDLEPLDPVGTPDDLRWLHALVWPGDEARAARLAAAVEAVRASPRPTVVRGDLIDELPALAARAPAGATLVVFHSAVLHYLPPARREEFAGLVRSVLAERDGPGHWISQEHHGVLPWITAPEHRSLGPGDPMLLTLALDERPVALTGPHGQSVHWLRPPLP
>NZ_CP006871.1|WP_020929266.1|4822538_4823963_-|hypothetical-protein
MASNRPAPHAPSAYGLGGPADFGGPVGFGGPAGFTVPTTVGDPAGVPAPTAVSGPDDVSAFPAVGGPTDDAAPAGAPQVPSPYGQFPGQRPPGEVFSHDLLTPEPPPPGAPGGAEPSAGPAGDGWPPADESDAGDASARPVRGKHRVAKQRSGGLARGGTVLGVGVIAAVGASGVAAAEDRPPVPISVPDPGGVVDDATGALQDAGPRAADAGAAPVATPAGTDSATEGSAPSVGPDASRPQGDDATAGGAPGAGPAEALRHRILQQADGRPGATEAETGSDADAGPDAARDAGPDAGPADEAAPDAASDAASGTASDAAAEPAAPASPARPVASDDRPADEAGTAVAPVSSYTLTTGFGQAGDRWAADHTGQDFTAPTGTLVRAVHDGTLTQAGWAGGYGYRIVLTLDDGTQLWFCHLSSMVKTTGRVHAGDVIGRVGATGNATTPHLHLEVRPDAGAPTDPLPWLRDRGVTV
>NZ_CP006871.1|WP_016573658.1|4821465_4822431_-|aldo/keto-reductase
MTVTHAQSSAPTPKSLGSLSVSPLCLGGNVFGWTADEAESFAVLDAYVAGGGNFIDTADVYSAWVPGNKGGESETVLGNWLAARGNRDDVVIATKVGARPDLKGLSAATIKTAVDLSLTRLRTDHIDLYYTHYDDESVEVGEFLTALDDLVRAGKVREIAASNISARRLQESLDFSAREGVARYVALQPHYNLVSRDTYEGELADVAARNGVAAVPYYALASGFLTGKYRPGSSVDSARAGKAAEYLETDRGRRVLQALDTVAAAHEAEPSTVALAWLAAQPTVAAPIASARTLAQLPALLAVTELTLTDVELALLTEASA
>NZ_CP006871.1|WP_026247493.1|4821035_4821338_+|hypothetical-protein
MAGIPTSVVAATGLVGGYGVARWTKKRPLGGVALAAAGAVAARGWQQKAGTKAAAALSGAYVAAFAGSHPLAKKIGAWPSVFAVAGGVALASWAVADRRG
>NZ_CP006871.1|WP_016578805.1|4819667_4820951_+|PrsW-family-intramembrane-metalloprotease
MYPSPPPLPAHSAGPSSYTPAEVPDGPRRRSAPWRSKTVRAVALAALLALSGVLILGIVRRQTGTEGLLVGLGLAVFPVPLLIAAFCWLDRIEPEPWRNLAFAFAWGACAATLVAVLANGFATDWLANNIASASPTDAQAWGSTVVAPIVEEVMKAAAIVLLYRFRRRDFDGITDGIVIAGITATGFAFTENILYLGSAFGEDRSMGHTGLDSVTAGTFFVRIVVSPFAHPLFTILTGLAFGIAATRYPRRRAARAALVLLGLTTAVLLHGVWNAASSLGDAGFLTVYGVCMVPVLLTLTWLALWARRQELLSVRVYLAPYTAAGWLAPPEPTALASLRTRALARDLARRTHGPAAARAVTAYTTLATALSFHRRRAHLAGPSPDFAARERELLELLWQYRTWAGPALLQAWACGTGAPGQRAGDQR
>NZ_CP006871.1|WP_016578804.1|4818721_4819579_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MSENPATPETAAADDVTAAHAPVTAAPPTRPLGATAASAAVPRRGAPMFPDGTGPAADPAGSHHERRIRSFQPRRSRVTASQAEALRRLWPTWGMDIDGLSRLDLDAFFGGLPVVLEIGFGMGEATAQMAAADPGTGILGCDVHTPGQGNLLRLAERNGLSNVRVANGDAIILLREMLAPGSLAGLRVYFPDPWPKKRHHKRRLIQPEFVALAATRLAPGALVHCATDWEPYAEQMLEVLSAEPALENLHSGYAPRPEFRPLTRFEGQGLDKGHTVHDLLFRRRG
>NZ_CP006871.1|WP_016578803.1|4817299_4818547_+|L-2-hydroxyglutarate-oxidase
MAAYDCDVLVIGAGIVGLSTARALTRAAPGMRVVVLEKEPAAARHQTGRNSGVIHSGIYYPPGSLKARFALQGAAEMVKFCTAHAIPHEVTGKLIVATERSELPRLHGLIQRGREHGLPVRELGPAQIAEHEPEVRGLAAIHVGTTGICDFGAVARQLGRLAEEDGAHVVLGEEVTAIGRRPGRVAVRTAGGTVYRARALVNCAGLHCDRVARLAGDDPGMRIVPFRGEYYTLAPERAALVRGLVYPVPDPAFPFLGVHLTRGVDGSVHIGPNAVPALAREGYDWRTVRPAELAGTLAFPGSWRIARRHWRYGAGELHRSLSRGAFTDAVRRLLPDARAEDLLPAPAGVRAQAVLPDGTLVDDFLFAESPGMIHVLNAPSPAATASLPIGREVARRVTRLLGLPAREVGGEGAGE
>NZ_CP006871.1|WP_016571945.1|4815577_4817026_+|hypothetical-protein
MSRDTRGPNEKLGTVLALAGISNAGLARRVNDLGAQRGLTLRYDKTSVARWVSKGMVPQGAAPHLIASAIGSKLGRPVPLHEIGLADADPAPEVGLAFPRDVGAAVRSATELYRLDLAGRRGSGGGIWQSLAGSFAVSAYATPASRWLISPADSSVAREAAEARDKDAAAAGDAGAPQHVGHSDVTKLREAAEDARRWDSKYGGGDWRSSMVPECLRVDAAPLLLASYSDEVGRALFGATSELTRLAGWMAFDTGQQEAAQRYYIQALRLARAAADVPLGGYVLASMSLQATYRGFADEGVDLAQAALERNRGLATARTMSFFRLVEARAQAKAGEARACEVALKASEGWLERSRSGDPDPSWLDFYSYERFAADAAECYRDLRLPRQVRRFTEQALSRPTEEFVRSHGLRLVVSAVAELESGNLDAACAAGTRAVEVAGRISSARTTEYVRDLLHRLEPYGDEPRVVELRERARPLLAAPA
>NZ_CP006871.1|WP_016571944.1|4812800_4814873_-|asparagine-synthase
MRWLVGWSSAATTNKECRSLLPVGAQLLWGDPDPLWAVGDWRPHEVRVVQADPETRLAVFGVCGATDDQLKVGLFAARGGALRHLTAWPGSYTAVVQVGRRITITGDLAGARPVFHTRWAGGTAYATAALPLADLVEASLDVGHLAALLACPDAPEALGTGTPYDGVRRIPPGHALVLRTGSSEIASYEPPASLAVAAPQLAPEHAVEGVREALVEAVRARLAAPRFAPDPEGLDRLDPGPVPGMGPAERRAARGGPAPGIGADLSGGSASGTLALLAAGLPGQPGRINGHGERLLAVTFNDLAAHGSRAQHEAELDRARGIADNPRLHHVVVAAGDEALPFTGLDVLPLTDEPGPSLTLAARHRRRLLAGGADHFVGNGARHVLDAHPARLADLLMDRRRRHLLRPVTALARADGSSAHSVLVPFTVYRAARKLARTPYATGIAEAARRLMERQFADEPVAGGAVDASLAALAWCRPGPAARWLTGEALAEVSVRLGDAARRSPAAGRPGERRARAALARQAADHRIFEQAAEVRNQRLHAPFLDNQVVLACRALPDTLRVQPGARAAVLRSVLAGAGVRDLPAGWGAAAHHPHTAAARAGLRVTVDWLLQLFDAPLLADAGLIEARVVRKALRTAAEGAPLPLDGLAELVSTEMWLRRLLARRGSCWTGAEAPRQRALAGGVPRARLS
>NZ_CP006871.1|WP_045788070.1|4830196_4830745_-|hypothetical-protein
MARVTAAAVTVSALAASLAGCMSVSDPGQPTPSGSTARHGDEKGRPHRPGGLTVDGRGGGPHRAGHGGPARPADGGAGPAGEDDGPAQPSPSRSAHPSSPPSAPAPGAPSAPPAGPSGGPASPAGGAQASGPSPLSPKLSPKSSGSAGSSTAAASSGARSPVPGSGSASLSAGVSPQVEWDA
>NZ_CP006871.1|WP_016578497.1|4830965_4831316_-|metallopeptidase-family-protein
MLEMTREEFEELVAEALDRIPPELTRLMDNVAVFVEDEPPADDPDLLGLYEGTPLTDRGEWYAGVLPDRITIYRRPTLRMCDTREDVVAETEVTVVHEIAHHFGIDDARLHALGYG
>NZ_CP006871.1|WP_106966098.1|4831612_4833046_+|metallophosphoesterase
MLAVSVLGAWLGLLALGGVRAPVGPVDTSMALRPSLAGGTRITVPPLGDLELDSHAAPIRLDVDVDRLDPARSAELVDHPERFAGLQAQVTHDVLRGAAGLVVASCAAAVCGASALGLVVYRRPRRALAAGGLALALLTASGATAYATWNPQSVLEPRFSGLLSSAPSVVGNARSIVSEFDVYQKELARLVTNVSKLYDTASTLPAYQPDPTTLRVLHVSDIHLNPASWHLIASLVKQYRIDVIIDTGDTMDHGSAAENHFLDPASTLGAPYVWVRGNHDSRGTQRYLTARKHVTVLDGGRVAQVAGVRIAGVGDPQFTPDRSVAPAGDAAERTAGGRLADALRTQRLAGTPVDIALAHNPTAVAETDGLVPLALAGHVHHREITTLPQGTRLMVEGSTGGGGLRAVQDKQPAPVQASVLYLDRTTKRLQAWDEITLGGLGLTRAEVSRHLPRENQPAAPGGTPSAGPSATASDGPG
>NZ_CP006871.1|WP_037632267.1|4833557_4834637_-|membrane-protein
MRDHEEDAAPHGAHGRPRSWSQRWTAFTASPFLPAVVLMFILAAAAGLFAGSYTYAMANPAPRHIPTAVVTTPAAPQQRAFVAGMEQALNASLQLTDYATYADARNAVDEQREFAVLRAHGRGVGLDVSGASGASVAQLLSEAAAKVGPATGVSVTVRDVTPLQHGDPRGLALFYISLAAVIIGFVGAIQLSVHARALTPAERTAFTVANALLGGFAIAAVADWWLGALRLPFVESWMILALTMFTSGMVFTMFNTLMGRWAMIPTWGLMVLLGNPSSGGAVSWPLLPSALGQIGRWLPPGASVNAQHTAVYFGGHQHAFPFLVLAGWSALSCAVFWGWRHRHPGGREPSPPPAHAADA
>NZ_CP006871.1|WP_020929262.1|4834864_4838860_+|ATP-dependent-RNA-helicase-HrpA
MSSQPASAPSDGAASTLPSLLKRLPELMLRDQQRLGRRLDGARRIRKPEARAAVLTEIAAGLDEAELRVAQRREAMPAVSYPPELPVSQKKDEILAAIRDHQVVIVAGETGSGKTTQIPKICLELGRGVRGLIGHTQPRRIAARTVAERVAEELKTPLGEAVGWKVRFTDQVGGDTLVKLMTDGILLAEIQTDRELQQYDTIIIDEAHERSLNIDFILGYLAQLLPKRPDLKVVITSATIDPERFSRHFGDAPIVEVSGRTYPVEVRYRPLLEEGGQDPDRDQITAICDAVDELQAEGPGDVLVFLSGEREIRDTADALNKKNLPATEVLPLYARLSHAEQHRVFQRHSGRRIVLATNVAETSLTVPGIKYVIDPGMARISRYSFRTKVQRLPIEPVSQASANQRKGRCGRTSDGICIRLYSEDDFLTRPEFTDAEILRTNLASVILQMTAAGLGDIEKFPFIDAPDRRNIKDGIDLLRELGALDATQKDARKRLTPLGRKLSQLPVDPRLARMVLEADRNGCAREVMVIAAALSIQDPRERPSDKQQQADQQHARFKDETSDFLAFLNLWSYVREQQKALSSSAFRRMCRTEFLNYLRIREWQDIYTQLRTVAKGMGVHLNETDAAPDHIHTSLLAGLLSHIGLKDADAKNEYLGARSAKFAVFPGSALFKKPPRWVMSAELVETSRLWARVNARVEPEWIEPLAEHLVKRTHSEPHWEQKMAAVMAYERVTLYGVPIVAQRKVNYGRIDPEVSRDLFIRNALVEGDWRTHHQFFHDNRKLLGEVEELEHRARRRDILVDDETLFDFYDQRIPADVVSGAHFDAWWKKKHREEPELLNFEHSMLINESAEAVTKDDYPDSWRQGKLKFKVTYQFEPGADADGVTVHVPLQVLNQVAAEGFDWQIPGLREQLVTELIRSLPKPIRRNYVPAPNFAARFLDSTVPLQGALTTSLAAGLQRMVGVPVEAADFDLAKVPDHLKITFRVVDERRRKLAEAKDLEALRLQLKPKTRAAISRAFEQAAERPGKDRRGDRGETPPAGPEQRTGLTSWTIGTLPRTFETRRAGQPVKAYPALVDEGSSVAVRLFDTEAEQLTAMWAGTRRLILLNVPANPAKFAQDKLSNQQKLALSRNPHGSIAALFEDCVTAAADRLIAARGGPAWDEEAFRKLFDAVRADLVDATLKTIQQVQEVLAAWQACERRLKATSFASLLPSLADVKEQLAELIKPGFVTAHGAKRLPDLMRYLVAADRRLTQLPTNAERDRSRMAKVKEMQDEYAWLLEQFPQGRPVPAAAREIRWMIEELRVSYFAHALGTAYPVSDKRIMKAVDAAAP
>NZ_CP006871.1|WP_016575269.1|4839263_4839500_+|hypothetical-protein
MTTAVRHETRALLRAHLSAALRYGYRHLTRQCPVCHQLLRLAMEPHDARSGPVTPPSAPSPSRAACEPPAEDESPGLR
>NZ_CP006871.1|WP_003980577.1|4840030_4840237_-|developmental-transcriptional-regulator-BldC
MTARTPDAEPLLTPAEVATMFRVDPKTVTRWAKAGKLTSIRTLGGHRRYREAEVRALLAGIPQQRSES
>NZ_CP006871.1|WP_016575268.1|4840739_4841576_-|hypothetical-protein
MALASSVRVPYVAYLRVYEPLAAFPEPERSYWARYATREVTPTAEDEQRRALADLLPTPPVPVPVHESGDAFVAVVDDVTCVCPWRTRLRGWQALEALEELLPASVLDAALPPVVRRQAATDYERWRERNPDARPWIRAATWHVPVRWFVLFDDDEREYAKGDQVPALRYRTPMVQARRRVARGLRTLRDALEEGPLIDGLVDVGRWLEDFHPRSLVELDYGGLVHAVPEGQLVEDRSAAEVAEGLAALREGDGERAGAAYEKLSQRWSAVRERQFSS
>NZ_CP006871.1|WP_078487424.1|4841766_4842885_+|Glu/Leu/Phe/Val-dehydrogenase
MGVTTVTDVRPAAADATGGVLQTLFRTEQGGHEQVVLCQDRASGLKAVIALHSTALGPALGGTRFHPYASEEEAVLDALNLSRGMSYKNALAGLDHGGGKAVIIGDPELIKTDELLLAYGRFVASLGGRYVTACDVGTYVADMDVVARTNRWTTGRSPENGGAGDSSVLTAYGVFQGMRASAQHLWGDPSLRDRKVGVAGVGKVGHHLVEHLLKDGAEVVITDVRAESVDRILDRHPQVTAVADTAALIRTPGLDVYAPCALGGALDDVTVPVLTAKVVCGAANNQLAHPGVEKDLSDRGILYAPDYVVNAGGVIQVADELHGFDFDRCKAKAAKIFDTTLAIFAHAKADGIPPAAAADRLAEARMAEARRA
>NZ_CP006871.1|WP_016575266.1|4843195_4843444_+|DUF3073-domain-containing-protein
MGRGRAKAKQTKVARQLKYSSGGTDLSRLADELSTQSNQQPPNREPFEGEDEDDDPYAQYAERYNADDDEEEGHSSNQRRRA

Crispr_ID: NZ_CP006871_6

• CRISPR_ID: NZ_CP006871_6
• CRISPR_location: 5046720-5046899
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP006871_6

Consensus_repeat	Method
CGTTTCACGTGAAACCGC	CRT

spacers of NZ_CP006871_6

>6.1|5046738|39|NZ_CP006871|CRT
GGATTCTCGGCTGTTTCACGTGAAACCCTGGCCTTCTTA
>6.2|5046795|27|NZ_CP006871|CRT
TCCTAGAAAAACGTCGCGGCTCGGCGG
>6.3|5046840|42|NZ_CP006871|CRT
GGAGTGTGAAACCACGGAGAGCGACCGCCGCGCACCGCGGAC

CRISPR arrays and Neighbor proteins around NZ_CP006871_6

CRISPR arrays

The CRISPR arrays of NZ_CP006871_6

>merge|NZ_CP006871|6|5046720-5046899|CRT
CGTTTCACGTGAAACCACGGATTCTCGGCTGTTTCACGTGAAACCCTGGCCTTCTTACGTTTCACGGTGGAGCGCTCCTAGAAAAACGTCGCGGCTCGGCGGTGTTTCACGTGAAACCGCGGAGTGTGAAACCACGGAGAGCGACCGCCGCGCACCGCGGACCGTTTCACGTGAAACGGG

>NZ_CP006871|6|2|5046720-5046899|CRT
CGTTTCACGTGAAACCAC	GGATTCTCGGCTGTTTCACGTGAAACCCTGGCCTTCTTA
CGTTTCACGGTGGAGCGC	TCCTAGAAAAACGTCGCGGCTCGGCGG
TGTTTCACGTGAAACCGC	GGAGTGTGAAACCACGGAGAGCGACCGCCGCGCACCGCGGAC
CGTTTCACGTGAAACGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_016570496.1|5056570_5057089_+|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NZ_CP006871.1|WP_016579328.1|5041244_5042288_+|aminoglycoside-phosphotransferase	unknown	unknown	gnl|CDD|270702
NZ_CP006871.1|WP_037633584.1|5044302_5045949_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP006871.1|WP_020929882.1|5046902_5047703_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP006871.1|WP_016579323.1|5035971_5037438_-|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl|CDD|237001
NZ_CP006871.1|WP_016575321.1|5048965_5050105_-|TrkA-N-domain-containing-protein	unknown	unknown	gnl|CDD|367001
NZ_CP006871.1|WP_016575320.1|5047879_5048857_-|NAD(P)H-quinone-oxidoreductase	unknown	unknown	gnl|CDD|176180
NZ_CP006871.1|WP_016575323.1|5051669_5052581_-|molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl|CDD|133000
NZ_CP006871.1|WP_044377009.1|5046034_5046595_-|bacterial-proteasome-activator-family-protein	unknown	unknown	gnl|CDD|378489
NZ_CP006871.1|WP_016579326.1|5039988_5040648_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP006871.1|WP_016570495.1|5055123_5056323_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl|CDD|213783
NZ_CP006871.1|WP_016579327.1|5040775_5041192_+|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|378988
NZ_CP006871.1|WP_016579322.1|5034631_5035483_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|240046
NZ_CP006871.1|WP_016579324.1|5037459_5038443_-|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl|CDD|223101
NZ_CP006871.1|WP_020929883.1|5052635_5054093_-|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl|CDD|237001
NZ_CP006871.1|WP_016575322.1|5050101_5051673_-|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl|CDD|238452
NZ_CP006871.1|WP_016570494.1|5054092_5055127_-|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl|CDD|223101
NZ_CP006871.1|WP_016570497.1|5057186_5057777_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380061
NZ_CP006871.1|WP_020929879.1|5042321_5043989_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP006871.1|WP_016579325.1|5038445_5039663_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl|CDD|213783

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_016570496.1|5056570_5057089_+|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.61299e-29
NZ_CP006871.1|WP_016579328.1|5041244_5042288_+|aminoglycoside-phosphotransferase	gnl|CDD|270702	cd05153, HomoserineK_II, Type II Homoserine Kinase. This subfamily is composed of unusual homoserine kinases, from a subset of bacteria, which have a Protein Kinase fold. These proteins do not bear any similarity to the GHMP family homoserine kinases present in most bacteria and eukaryotes. Homoserine kinase catalyzes the transfer of the gamma-phosphoryl group from ATP to L-homoserine producing L-homoserine phosphate, an intermediate in the production of the amino acids threonine, methionine, and isoleucine. The Type II homoserine kinase subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	4.52156e-38
NZ_CP006871.1|WP_037633584.1|5044302_5045949_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.50195e-124
NZ_CP006871.1|WP_020929882.1|5046902_5047703_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	9.7715e-08
NZ_CP006871.1|WP_016579323.1|5035971_5037438_-|2-oxo-acid-dehydrogenase-subunit-E2	gnl|CDD|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	1.44517e-159
NZ_CP006871.1|WP_016575321.1|5048965_5050105_-|TrkA-N-domain-containing-protein	gnl|CDD|367001	pfam02254, TrkA_N, TrkA-N domain. This domain is found in a wide variety of proteins. These protein include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.	3.72659e-25
NZ_CP006871.1|WP_016575320.1|5047879_5048857_-|NAD(P)H-quinone-oxidoreductase	gnl|CDD|176180	cd05276, p53_inducible_oxidoreductase, PIG3 p53-inducible quinone oxidoreductase. PIG3 p53-inducible quinone oxidoreductase, a medium chain dehydrogenase/reductase family member, acts in the apoptotic pathway. PIG3 reduces ortho-quinones, but its apoptotic activity has been attributed to oxidative stress generation, since overexpression of PIG3 accumulates reactive oxygen species. PIG3 resembles the MDR family member quinone reductases, which catalyze the reduction of quinone to hydroxyquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_CP006871.1|WP_016575323.1|5051669_5052581_-|molybdenum-cofactor-guanylyltransferase	gnl|CDD|133000	cd02503, MobA, MobA catalyzes the formation of molybdopterin guanine dinucleotide. The prokaryotic enzyme molybdopterin-guanine dinucleotide biosynthesis protein A (MobA). All mononuclear molybdoenzymes bind molybdenum in complex with an organic cofactor termed molybdopterin (MPT). In many bacteria, including Escherichia coli, molybdopterin can be further modified by attachment of a GMP group to the terminal phosphate of molybdopterin to form molybdopterin guanine dinucleotide (MGD). This GMP attachment step is catalyzed by MobA, by linking a guanosine 5'-phosphate to MPT forming molybdopterin guanine dinucleotide. This reaction requires GTP, MgCl2, and the MPT form of the cofactor. It is a reaction unique to prokaryotes, and therefore may represent a potential drug target.	4.53461e-32
NZ_CP006871.1|WP_044377009.1|5046034_5046595_-|bacterial-proteasome-activator-family-protein	gnl|CDD|378489	pfam10759, DUF2587, Protein of unknown function (DUF2587). This is a bacterial family of proteins with no known function.	1.98313e-95
NZ_CP006871.1|WP_016579326.1|5039988_5040648_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.57432e-64
NZ_CP006871.1|WP_016570495.1|5055123_5056323_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl|CDD|213783	TIGR03181, PDH_E1_alph_x, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	2.55366e-165
NZ_CP006871.1|WP_016579327.1|5040775_5041192_+|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	3.45106e-09
NZ_CP006871.1|WP_016579322.1|5034631_5035483_-|GNAT-family-N-acetyltransferase	gnl|CDD|240046	cd04690, Nudix_Hydrolase_31, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	3.07117e-33
NZ_CP006871.1|WP_016579324.1|5037459_5038443_-|alpha-ketoacid-dehydrogenase-subunit-beta	gnl|CDD|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	8.08893e-158
NZ_CP006871.1|WP_020929883.1|5052635_5054093_-|2-oxo-acid-dehydrogenase-subunit-E2	gnl|CDD|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	3.04441e-150
NZ_CP006871.1|WP_016575322.1|5050101_5051673_-|molybdopterin-molybdotransferase-MoeA	gnl|CDD|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.1377e-100
NZ_CP006871.1|WP_016570494.1|5054092_5055127_-|alpha-ketoacid-dehydrogenase-subunit-beta	gnl|CDD|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	1.67263e-157
NZ_CP006871.1|WP_016570497.1|5057186_5057777_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	6.63609e-21
NZ_CP006871.1|WP_020929879.1|5042321_5043989_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.44887e-125
NZ_CP006871.1|WP_016579325.1|5038445_5039663_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl|CDD|213783	TIGR03181, PDH_E1_alph_x, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	0

Protein sequences

>NZ_CP006871.1|WP_044377009.1|5046034_5046595_-|bacterial-proteasome-activator-family-protein
MDMPMNERSQENQHVLVVGPDGMALGSAGSGDGDEGGEPRETPVTDMVEQPAKVMRIGSMIKQLLEEVKAAPLDEASRVRLKEIHASSVKELEDGLAPELVEELERLSLPFTDESVPTEAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLEQMRRALPPGLTAEGHPEHPGHDGARSGPYL
>NZ_CP006871.1|WP_037633584.1|5044302_5045949_+|serine/threonine-protein-kinase
MSQDGAQGQFEGRSVGGGRYQLRDLLGAGGMASVHLAYDSVLDREVAIKTLHTELGREQAFRERFRREAQSVAKLTHTNIVSVFDSGEDQLDGGMVPYIIMEYVAGQPLRSVLDSDIAQHGAMPTEKALKITADVLAALEASHEMGLVHRDIKPGNVMMTKRNVVKVMDFGIARAMQSGVTSMTQTGMVVGTPQYLSPEQALGRGVDARSDLYSVGIMLFELLTGHLPFDADSPLAIAYAHVQEEPPVPSTINRSLPPAVDALVARALRKNPNERFPTAEAMRDECLRIAGSGQSGATPLIISEGPRARTSGASVSSAVFPTASGNPHTPVPPSVQQPYQPTQAAFGPSTPPPVNSPYPTPAPAPAPTPPPFTGGFQAPPPFPGPPSPVTGAMPPARPRKNNSGVIVVAAVVGVVVVTAIAIGIGLSAGSGGSSTGGSDSPTFAYSPSPTASVRPEDKTATIQASQCTNPTPSYSQKGKVLFPSFKFKNLESVEACIKAAGWKYKIVKEENDAIWGKNTVTDQTPAAISWWDPRSNDTVELTISTGHN
>NZ_CP006871.1|WP_020929879.1|5042321_5043989_-|serine/threonine-protein-kinase
MAPTQRPQGPSDPDATGSNVSDAPELWGNGGLVGDGRYRLTRRLGRGGMAEVFAAEDVRLGRTVAVKLLRADLAEDPVSKARFTREAQSVAGLNHHAVVAVYDSGEDFVSGNTVPYIVMELVEGHTIRDLLLNAEAPPPDQALIIVSGVLEALAYSHQHGIVHRDIKPANVIITNSGAVKVMDFGIARALHGAQSTMTQTGMVMGTPQYLSPEQALGKTVDTRSDLYATGCLLYELLAQRPPFTGETPLSVVYQHVQDMPVPPSQVADAVPPELDGLVMRSLAKDPDDRFQSAEEMRGLVQYSLQMLHEQGGHTGTWNTGPVALHEGGHTMALRGGAAETSVMSHADAGKTTAQPILTPGMRDDDGGFEGGYRQAKGGRGKIWLIAVLALIAIAVGVAFALQNTNSNGHKPKTPVTQSPQPSQSDETTQPPTDEPSTTDTYPGSTSGGGNPYTHRPTHQPSTQPSSEPTPSSQPSSEPPTSTTGGTTTGGTTDGGTTNGGTTDGGTTNGGTTDGGTTNGGTSNGGTTNGGTTNGGTNNGGTTNGGTTPLGGATGG
>NZ_CP006871.1|WP_016579328.1|5041244_5042288_+|aminoglycoside-phosphotransferase
MLRSSVVRSASTPDRDTLGSLLRHYDGAGAPLSCEPVAEGLLNHGYFLATTRGRYFLKHHLDGDRAALTRQHRATRRLAGCGLPVVPPVTGTDGRTFTVLDGRHYALHPWRTGRHLSGTALTVGQSRRLGGLLGLVHTTLEQVMADEPAPPRPPGTDAAADPERTFETIDELLALARGARPRTSFDELAEHRLLERRALLERQAHRRPAPGAEPPAGWVHGDFHPLNVLYRGTEPGAIVDWDRLGVHPRAEEAVRAAVIFFVRPCGTLDLSKVAAYAAAYRSVCGAGADELAAAVHRVWWERLNDFWMLTWRYRLGDRRTDPQFPAAAALAVWWTREFPAVRRAFTG
>NZ_CP006871.1|WP_016579327.1|5040775_5041192_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MPTDVFRAIELLSSTPYGRVSASRRALPFTTVTRHVVVDGRVLLRLHRGYEYHRALDGSVVAYEADNVNSGARDTWSVQFTGTARVIEPTPVERELFGRTPRLADGVPYDAVFLRIEPEFVTLHHLTDVPVFGYAHPL
>NZ_CP006871.1|WP_016579326.1|5039988_5040648_+|response-regulator-transcription-factor
MREDGKITVFLLDDHEVVRRGVHEMLSVEDDIEVVGEAGTAADALVRIPATRPDVAVLDVRLPDGSGVEVCREIRAQDEEIKCLMLTSFADDEALFDAIMAGASGYVLKAIRGSELLSAVRDVAAGKSLLDPVATARVLERLRDGNAAKGDDRLANLTEQERKILDLIGEGLTNRAIGERLHLAEKTIKNYVSSLLSKLGMERRSQAAAYVARMQAERR
>NZ_CP006871.1|WP_016579325.1|5038445_5039663_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MTVEGTAERKTARGGSKRTTAKKTTPAKKATQSKAGNSAGPDQAEQDQLVQLLTPEGTRVEHPDYTIDLSPEELRGLYRDMVLTRRFDAEATTLQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNHGGWDPNSNNFHLYTIVIGSQTLHATGYAMGVQKDGADSAVIAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEKQTRVPLYQRAQGYGFPGVRVDGNDVLACLAVTKAALDRARTGQGPMLIEAFTYRMGAHTTSDDPTRYRPDEETLAWEAKDPILRLRKYLEAEGLVDDAYLAAIDEESDVLGKRVRDVVRAMPDPDHLAIFENVYADGHALVDEERAQFAAYQASFADADAAAEGN
>NZ_CP006871.1|WP_016579324.1|5037459_5038443_-|alpha-ketoacid-dehydrogenase-subunit-beta
MAVHEKITIAKAINASLRASMEADPKVLIMGEDVGKLGGVFRVTDGLQKDFGEDRVIDTPLAESGIVGTAIGLALRGYRPVVEIQFDGFVFPAYDQIVTQLAKMHARALGKVKVPVVIRIPYAGGIGAVEHHSESPEALFAHVAGLKIVSPSNSSDAYWMLQQAIAGDDPVIYFEPKRRYHDKSRLDTESIPDPLHKARVTRAGSDLTLVAYGPMVKVCEDVAKVAAEEGKSVEVVDLRSISPIDFDTVQSSVEKTGRLVVVHEAPVFFGSGAEIAARITERCFYHLEAPVLRVGGFHAPYPPSRLEDEYLPGLDRVLDAVDRALAY
>NZ_CP006871.1|WP_016579323.1|5035971_5037438_-|2-oxo-acid-dehydrogenase-subunit-E2
MTAGTAGAAHTQRIREFKMPDVGEGLTEAEILKWYVKAGDTVADGQVVCEVETAKAAVELPIPYDGVVHALHFDEGTTVDVGTVIIAVDTDPGAGPVGEAPGEAAAPAEEDDAEPQGRQAVLVGYGAAPSSTKRRARKQQPGVPAQSEPVTAGLQAELNGHSAPAPAATPVAVPVAPAAPAAVVPAAERPLAKPPVRKLAKDLGIDLATVVPTGPGGVVTRDDVYAAAAPAETAVPAAPEVAVPTAVAPVAAFDAARERRVPVKGVRKATAQAMVASAFTAPHVTEFITVDVTRTMKLVQELKQDPDLAGLRVNPLLLVAKAFLVAIKRHPEVNAAWDEATQEIVYKDYVNLGIAAATPRGLLVPNIKDAGAKTLPQLATELGELVATAREGKTSPAAMSGGTVTITNVGVFGVDTGTPILNPGESAILAVGAIKLQPWVHKGKVKPRHVTTLALSFDHRLIDGELGSKLLADIAAILERPKRLITWG
>NZ_CP006871.1|WP_016579322.1|5034631_5035483_-|GNAT-family-N-acetyltransferase
MSSHTVIRRYRDADQDAVCDLWSRASKQAHPFIEGEGEGERARILREVHLVRAENWVAERDGAVIGVLGLRAGDDAGAEIDGLFVAPEAQGAGTGRELVEHAAARYGALTLEVFEENARARRFSACLGFTERGRRIDDQTGHPLIAAEREAPLRSVSWLHVRDGRLLSVRTRGNDTFYLPGGKYEPGETAREALSRELSEELGLRIPAAELSEAFVVHDVAHGKNGRRLHMTCFTGGPQDIAPAPGREIAEYAWFDGHESSARCAPAHRQVVDRLVAQGRMSA
>NZ_CP006871.1|WP_020929882.1|5046902_5047703_-|hypothetical-protein
MASSLLVLAAALPVSLTAGPALATDRQATPAARPDATLDDFAAIPVLTGEFSTEQYPGRPGGLPDFPGTYDFRDFPDAFLGLSGALPGFPDHPGGPFRHEPRQHHHTHPFGLGFPWRSDPVPGLDEGAPDDSADADADVSEPPLPSAPPHAPAPEPTPPPTHRPKPHERTPSASADPSPHTSPAPRPHPARPHDLAVPPAPTPDRQAPTPAPEEDGDSTMAGPDPVASPYPLDAPGARVERVLPMGAGMALTGLGLAFLGLRLRRR
>NZ_CP006871.1|WP_016575320.1|5047879_5048857_-|NAD(P)H-quinone-oxidoreductase
MRAITIPEPGGPEALVWAEVPDPQPAEGEVLIEVAASAVNRADLLQRQGFYDPPPGASPYPGLECSGRIAAVGPGVHGWAVGDEVCALLSGGGYAEKVAVPAGQVLPLPPGVDLVTAAALPEVACTVWSNVFMIAHLRPGETLLVHGGASGIGTMAIQLAKAVGARVAVTAGGPEKLARCAELGADVLIDYREQDFVQEIRKATEGKGADVILDIIGAKYLQKNVKALAVAGRLAIIGLQGGVKAELNLAALIAKRAAITGTGLRARPISEKSAIVAAVREHVWPLIGNGQVRPIVDRALPMAEAAEAHRILDASGHVGKVVLTV
>NZ_CP006871.1|WP_016575321.1|5048965_5050105_-|TrkA-N-domain-containing-protein
MKLPSHDAAARETPEDRSHRVILPRRSPKAPIRQVARRLLMALLVLVATVFIVWIDREGYHDNAGGQLDLLDCVYYATVTLSTTGYGDIVPYSASARLLNILLVTPLRVLFLIILVGTTLEVLTERTREQWQLKRWRNALRDHTVIVGFGTKGRSAVQTLRATGLPRERIVIVDPSTKVVESAVAEGYAGVVGDATRSDVLLRAEIQRAHQIVIATQRDDTAVLVSLTARQLNKRANIVAAVREEENAPLLRQSGADAVITSASAAGRLLGLSVHSPSAGAVMEDLIQQGSGLDLVERPVVKAEVGKSVRETNDLVVSVLRGHRLLGYDDPQASPLQTADRLITIVRAAPAEESAVPGKPPAKPTLPGTAVSPMRPADD
>NZ_CP006871.1|WP_016575322.1|5050101_5051673_-|molybdopterin-molybdotransferase-MoeA
MTDGEHGDPFGDEFADALALVNGTASTRGRSGSADRPGPSGGAPAGHAAGCAGPPPTGGAPGSGHVEEEYSATCGDARGAGSARPATRSSGHAVTPWRTARDLAERAVPGPVGPGTAELADALGRTLAAPLKALTDLPSFDTSAMDGWAVAGPGPWRVDRAADDTGPGSDAGILAGHATTAVLPDGHALPIATGARIPTGATAVLRSEHGEVLELPDGRARLYAPRPVPPGQDIRPRGQECRCGDQLLPAGTLVTPAVLGLAAAAGYDELAVHPRPRVEVLVLGDELLRDGLPEGGRIRDALGPMLVPWLRALGAEAAPPRHLGDDAEALHEALAGSTADLVITTGGTASGPVDHVHPTLQRLGAELLVDGVAVRPGHPMLLARLAPRRHLVGLPGNPLAAVSGLLTLAEPLLRTLAARHPAAPYRVPLAAAVPGHPRDTRLVPVAYRDDDRHGLVAGPLHFHGPAMLRGIAAADAMAVIPSGGAERGTEVELLELPWPTGWSAGWPTPDTCYDPAAPTGGTA
>NZ_CP006871.1|WP_016575323.1|5051669_5052581_-|molybdenum-cofactor-guanylyltransferase
MSDHTDYDAIVLAGGAARRLGGADKPALAVGGRALLDRVLAVCRDAAATVVVGPARPTARPVVQTREDPPGGGPLAALDAGLRHTTAPTVLVLSADLPFLTAATVRALLDAATASAASPRDGALLRDADGRDQPLVAAYRSVPLRRALDRLRVERGTLTDLPLRPLLSALVLARVPDASATASFDCDTWEDLGTARARIRDPGHVLDEWITAVKAELGIDLDVDTAALLDLARDAAHGVARPAAPLTTFLIGYAAGQQGRDVAELAQRAAALAERWAAEAATEEAAAARTTGGAPAGETKPAE
>NZ_CP006871.1|WP_020929883.1|5052635_5054093_-|2-oxo-acid-dehydrogenase-subunit-E2
MAVVREFTLPDLGEGLTEAVIVQWLVEVGEVVAVDQPVVEVETAKAMVEVPCPYGGVVTARFGAAGTEVPVGAPLVTVAVGAAPEDSAGRGSAPGSANGSASVAVPADPAPGAEGAGTDAAGSGNVLVGYGTSGAAARRRRILPSSAEAPARRSATPAPPATTNGTATNGTATNGTATGDAAGTAVADGPRTVAVISPLVRRIAREHDLDLREVRGSGRDGLILRTDVESAVRALGERQSAAARTAGTADAAGPVPGEERIPLKGLRGAAAEKFSRSRREIPDATCWVDADATDLLATRRAMNVPGAPKVSLLALLARICTAALARYPELNATVDTAAQEIVRLPAVHLGFAAQTDRGLVVPVVRDAQGRTVEQLSAEIARLTDAARAGKLSPAELSRGTFTLNNYGVFGVDGSTPILNHPEAAMLGVGRIAAKPWVHDGELAVREVVQLSFTFDHRVCDGGIAGGFLRYVADCVEQPALLLRSL
>NZ_CP006871.1|WP_016570494.1|5054092_5055127_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTTAAPTARKPATMAQALTRALRDAMADDPTVHVMGEDVGALGGVFRITDGLAEEFGEDRCSDTPLAEAGILGTAVGMAMYGLRPVVEMQFDAFAYPAFEQLVSHVARMRNRTRGAVAMPLTIRIPYGGGIGGVEHHSDSSEAYYLATPGLQVVTPATVEDAYGLLRAAIASDDPVVFLEPKRLYWSKADWSPDAPTAVAPIGRAEVRRRGSSATLLTYGPSLPVCLEAAEAARAEGWDLEVVDLRTLVPFDDDTVCASVRRTGRAVVVHESNGFGGPGGEIAARITERCFHHLEAPVLRVAGFDVPYPPPMLERHHLPSVDRILDTVARLQWESRWTEGRGA
>NZ_CP006871.1|WP_016570495.1|5055123_5056323_-|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MTVLEQPGSSRHTSDLAGPPPAWRPRVDPAPLLPDAEPYRLLGTDAAGRLDPGLLKRLYTELVRGRRYNTQATALTRQGRLAVYPSSTGQEACQVAAALALQEQDWLFPSYRDTLAAVARGLDPVQALTLLRGDWHTGYDPYEHRIAPLCTPLATQLPHAVGLAHAARLKGDDVVALAMVGDGGTSEGDFHEALNFAAVWQAPVVFLVQNNGFAISVPLAKQSAAPTLAHKAVGYGMPGRLVDGNDAPALHEVLTDAVRRAREGGGPTLVEAVTYRLEAHTNADDATRYRTDAEVESWRAHDPIALLERALTDRALLDDAFATATRDGAERLAADLRERMHAEASLAPMDLFDHVFTQQTSQLRSQAAQLRAELDAEAEGAEAPESATGTVAPAQEARP
>NZ_CP006871.1|WP_016570496.1|5056570_5057089_+|Lrp/AsnC-family-transcriptional-regulator
MPEEQMANPGGQPSAAPAPAPPAARPLDQIDRAILRLLRTDGRASIRSVAEQVHVSRANAYARINRLLDDGVIRGFSALVDQERAGQGASAYITLKIVQNSWRTVRKQLTTLPGAAHIALVSGDFDVLLLVHTKDNRELRELVLTRIQSIPEVLSTRTLLVFEETDLGVEEG
>NZ_CP006871.1|WP_016570497.1|5057186_5057777_-|TetR/AcrR-family-transcriptional-regulator
MTMAKRDAYTPDSLLAVSVEVFIERGYDGTSMEHLSKAAGISKSSIYHHVRSKEELLRRAISRALDGLFGVLAEADAQEGRAIERLEHVTRRVAEVLMDELPYVTLLLRVRGNTDTERWAMERRREFDHRVADLLKEAAADGDLRDDVDIRLATRLLFGMINSIVEWYRPGRGGAASRDEVAEAVVRTAFSGLRKV

Crispr_ID: NZ_CP006871_7

• CRISPR_ID: NZ_CP006871_7
• CRISPR_location: 6641333-6641425
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP006871_7

Consensus_repeat	Method
GGCCGGCGGCTGCGCCTGGAGCATCATCGT	CRISPRCasFinder

spacers of NZ_CP006871_7

>7.1|6641363|33|NZ_CP006871|CRISPRCasFinder
GCCGGCCTCCTTGGCGGGCGCCGGCGGGGCCGG

CRISPR arrays and Neighbor proteins around NZ_CP006871_7

CRISPR arrays

The CRISPR arrays of NZ_CP006871_7

>merge|NZ_CP006871|7|6641333-6641425|CRISPRCasFinder
GGCCGGCGGCTGCGCCTGGAGCATCATCGTGCCGGCCTCCTTGGCGGGCGCCGGCGGGGCCGGGGCCGGCGGCTGGGCCTGGAGCATCATCGT

>NZ_CP006871|7|5|6641333-6641425|CRISPRCasFinder
GGCCGGCGGCTGCGCCTGGAGCATCATCGT	GCCGGCCTCCTTGGCGGGCGCCGGCGGGGCCGG
GGCCGGCGGCTGGGCCTGGAGCATCATCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_016570486.1|6652530_6653490_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|224617
NZ_CP006871.1|WP_016575627.1|6631371_6631956_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016575395.1|6638710_6639760_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NZ_CP006871.1|WP_103377498.1|6637276_6638050_-|endonuclease-NucS	unknown	unknown	gnl|CDD|235114
NZ_CP006871.1|WP_016575625.1|6632853_6633702_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|224170
NZ_CP006871.1|WP_020931165.1|6634449_6637137_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_CP006871.1|WP_016570488.1|6650651_6651092_-|methylmalonyl-CoA-epimerase	unknown	unknown	gnl|CDD|213772
NZ_CP006871.1|WP_016570484.1|6654115_6654889_-|Ser-or-Arg-related-nuclear-matrix-protein	unknown	unknown	gnl|CDD|224924
NZ_CP006871.1|WP_016575626.1|6631975_6632548_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl|CDD|376665
NZ_CP006871.1|WP_037636828.1|6643770_6644793_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213235
NZ_CP006871.1|WP_016575394.1|6639987_6640311_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_037682847.1|6645995_6650444_-|hypothetical-protein	unknown	unknown	gnl|CDD|173412
NZ_CP006871.1|WP_016575396.1|6638191_6638584_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016577859.1|6644942_6645881_-|cellulose-binding-protein	unknown	unknown	gnl|CDD|274008
NZ_CP006871.1|WP_078486849.1|6640330_6641272_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|237030
NZ_CP006871.1|WP_016570485.1|6653515_6653992_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP006871.1|WP_016570487.1|6651256_6652432_+|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|180261
NZ_CP006871.1|WP_016575624.1|6633847_6634171_+|anti-sigma-factor-antagonist	unknown	unknown	gnl|CDD|132914
NZ_CP006871.1|WP_020931167.1|6641577_6642867_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213235
NZ_CP006871.1|WP_016577861.1|6642993_6643767_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|372253

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_016570486.1|6652530_6653490_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|224617	COG1703, ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism].	6.44027e-121
NZ_CP006871.1|WP_016575626.1|6631975_6632548_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl|CDD|376665	pfam01923, Cob_adeno_trans, Cobalamin adenosyltransferase. Cobalamin adenosyltransferase This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation.The EutT enzyme appears to be an adenosyl transferase, converting CNB12 to AdoB12.	1.28302e-78
NZ_CP006871.1|WP_016575395.1|6638710_6639760_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	2.56104e-51
NZ_CP006871.1|WP_103377498.1|6637276_6638050_-|endonuclease-NucS	gnl|CDD|235114	PRK03298, PRK03298, endonuclease NucS.	9.58219e-177
NZ_CP006871.1|WP_016575625.1|6632853_6633702_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein	gnl|CDD|224170	COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism].	1.5574e-124
NZ_CP006871.1|WP_020931165.1|6634449_6637137_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	9.22742e-13
NZ_CP006871.1|WP_016570484.1|6654115_6654889_-|Ser-or-Arg-related-nuclear-matrix-protein	gnl|CDD|224924	COG2013, COG2013, Uncharacterized conserved protein [Function unknown].	4.25639e-10
NZ_CP006871.1|WP_037636828.1|6643770_6644793_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	1.01023e-84
NZ_CP006871.1|WP_016570488.1|6650651_6651092_-|methylmalonyl-CoA-epimerase	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	2.14638e-51
NZ_CP006871.1|WP_037682847.1|6645995_6650444_-|hypothetical-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	4.72681e-24
NZ_CP006871.1|WP_016570485.1|6653515_6653992_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.95331e-13
NZ_CP006871.1|WP_016577859.1|6644942_6645881_-|cellulose-binding-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	2.34311e-06
NZ_CP006871.1|WP_078486849.1|6640330_6641272_-|ABC-transporter-permease	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	5.85151e-05
NZ_CP006871.1|WP_016570487.1|6651256_6652432_+|acetyl-CoA-C-acetyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP006871.1|WP_016575624.1|6633847_6634171_+|anti-sigma-factor-antagonist	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	6.74957e-21
NZ_CP006871.1|WP_020931167.1|6641577_6642867_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	1.83869e-95
NZ_CP006871.1|WP_016577861.1|6642993_6643767_-|ABC-transporter-permease	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	0.00387751

Protein sequences

>NZ_CP006871.1|WP_078486849.1|6640330_6641272_-|ABC-transporter-permease
MLLTAAAQPPAPPHPGPAPQHASVPQQQAPAPAPAPAPAANWQAATPGYVSPIPVRPTHLGHALAAEWTKIRSVRSTVWTLGVMTVLVLGIGVLVAVSVASMSTVGDTSPLFFGLFGMLLGVLCVLPLGVLVTSSEYGTGMIRTTLAACPNRGRVLTAKALVFFALTFVVTTVVTGLVALTDNAMISDISRVHVGAGEWLRSTVGIGLYVSFLGLLALAVGSLIRHSAGAITLMVGVVLLPFVLSMFMFADSLEGVRNFLMGYSIPNQLTVMYGNKFPFVDGGPSGWQPLWIVMGLAAVALGAAYATMRQRDV
>NZ_CP006871.1|WP_016575394.1|6639987_6640311_+|hypothetical-protein
MSPRRNRQRGANPPDRADHPGVGRYGFETTEEWHGEDWVVRPVGGAGAAKHYRCPGCDQEIPPGVPHVVTWPRHGDVDDRRHWHKACWNARNRRSARLQRSRNAPRY
>NZ_CP006871.1|WP_016575395.1|6638710_6639760_-|LLM-class-flavin-dependent-oxidoreductase
MRVGAFILAAQFPGQGQGEALHRAVRSAQIAEEAGLDEVWLAEHHFVPYGVCPQAATLAALLLGRTRRIGVGTAVSVLPTQHPVALGEQAALLHLASEGRFTLGVGRGGPWVDLEVFGAGLAAYEHGFPESLDLLLRWLREPRVGAAGERYAFREVAVVPRAAEALVDPDDPQGLTDGPPVVVACTSPSSVRLAAARGLPMLLGMHCDDEEKAEMVALWRSAALAAGRDPGEVAAAEHVSAGVVQVADGRPAAVETLTKAMPGWFRQGLGAHVTVDGRYRSMRDPLAYTELLCALHPVGPPELCADRLAATSERTGIRRFALMVEGSGDLAATEENVRRLGTEVLPQLV
>NZ_CP006871.1|WP_016575396.1|6638191_6638584_+|hypothetical-protein
MSLDVSPALLEQAERGEVDEAAFVDCVRTSLPYAWGMISSLVDRLKADGGEFADNQTPPPNEQARGQLLRALASDAIRGSLERHFGVRLAFQNCHRVAVFPLDPAVDQRLVRFTSVRGQLLNQSPELRDC
>NZ_CP006871.1|WP_103377498.1|6637276_6638050_-|endonuclease-NucS
MQPAKDPRRGCGGFRRKGTPGRGRIASAAPVRVAWRTMRLVIARCSVDYAGRLTAHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCSLKEGDGNVWTVVNKGGEKLIITLEEVMHDSSHELGVDPGLIKDGVEAHLQELLADRIETLGEGYSLIRREYPTAIGPVDILCRDADGQTVAVEIKRRGEIDGVEQLTRYLELLNRDPHLAPVKGVFAAQEIKPQARVLATDRGIGCVVLDYDALRGIEDDKLRLF
>NZ_CP006871.1|WP_020931165.1|6634449_6637137_+|hypothetical-protein
MDPNTTPGPEEHGQQDGPAGPPPPEATGRQGGSGGLARVVRLVSGNYLVTVNPVDGCEIQPCPPGERPAPPVKLDPQERAAAARAAQPPAPSGPLSFAGHEILLEERSEDIARLVRLLTRGRSVRVTGPAGSGRTRLLDAVAGSVADLAPDGVVRLSGYHRSVTDVLHALFAAVYRAPQHRPERPELLRLLGGVGAVVVLDDLEFGGAALDELLEATPECAFLFAATPDVPAPSADAHVEEVFVGGLSKDAGLRLLERAVDRPLTRDEKTWTTDLWFESEGLPLRFVQAAALLRQRDRARTAPGALDDGYGLFPEDGPADAADPEQRPGAPLPAVGEAAAPAPLLAERLGAAAQETLRFALALGGELPHQAHLPALTQDTHADAALGELLGCGLISPVGGHYRLAATVQEQLTEAGYAEGAAARAHAAAQHYAWWAGHPSVTPERAAAESDAVLAAMAVLTGSRENGHPAAAVLLARTAAPAFAAALHWSAWERSLRHGQEAARLAGEVAQEAYFHHDLGVLALCSGNVDRARAELEASIGLRGVLSDRDGAVAGRRALALVIDRSRAAAADAPTTLLASVGPAVAAGGTAGGQGAAEPHDPAAEASPDAVSTAKLQAVARPEGPASTVTARPAAGAARPAPSSGETTAALPAAKAAKTAAAAASAKSGGAAGGLGRGIRRTGRRNLIAAGAAVLVAAALGTALTLGMSSDTSSPHDDKVTTDQSPAAGGDSQEPAQDPGTGAGLPPTGSGTTRPGTPSAPGHRPTTAPTAPGTTGAPTTPTGDPTSGTTGPTGGPTSPTGRPTPPTHSPTSSPTDPTPTHKPTGTPTDPTPTQKPTDTPTGQPPTTSGGSSGGNPSGSNSAVAPSTSNGGAATASDTPPAPSDPSASSQGTPAG
>NZ_CP006871.1|WP_016575624.1|6633847_6634171_+|anti-sigma-factor-antagonist
MHIRGDHAELVVGGRLDVRSAADARTVLHAAVDSGRGDLVLDLTELDSWDATGLGVIMGAHRRAGRNNRRLVLRGVPPQMQRLLVATRLHRILAIEGGIEAESLPRV
>NZ_CP006871.1|WP_016575625.1|6632853_6633702_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein
MAKKLAVIGAGLMGSGIAQVSAQAGWDVVLRDVTDEALARGKGGIASSFEKFVAKGKLAAAAAEEALGRITTTTDLDAVADADIVVEAVFEKIEVKREIFQALDKLAKDDAVLASNTSAIPITKIAAATSRPERVVGTHFFSPVPMMQLCELVRGYKTSDETLATAREFAESVGKTCVVVNRDVAGFVTTRLISALVVEAAKLYESGVASAEDIDVACKLGFGHAMGPLATADLTGVDILLHATENIYTESQDEKFAPPEIMRRMVDAGDIGRKSGQGFYAH
>NZ_CP006871.1|WP_016575626.1|6631975_6632548_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MVNLTRIYTRTGDKGTTALGDMSRTAKTDSRIAAYADANEANAAIGVALALGALPEEVAAVLLRVQNDLFDVGADLSTPIVEDPKFPPLRVEQSYVDKLEADCDRFLAELEKLRSFILPGGTPGAALLHQACTVVRRAERATWAAMEEHGDTMNPLTATYLNRLSDLLFILARTANKEVGDVLWVPGGER
>NZ_CP006871.1|WP_016575627.1|6631371_6631956_+|hypothetical-protein
MVVTLIIACEVGFWVLLVVGLALRYLARMPRTGAAVLLLEPLLELALLIVTAIDLKNGSAADWKHGLAAVYIGYTVAYGHTTLTWADRLVAHRFAGGPPPVKRYGMDRFRHEARLWLRTVLMAAVAAALLQCAVWYVGGDGDVTSLREWQGMTVRLVVIHGVIALTYLIWQKKAPEDRAAPQEAPTRPRQKTLG
>NZ_CP006871.1|WP_020931167.1|6641577_6642867_-|ABC-transporter-ATP-binding-protein
MIEAVGLTKRYGPKTAVHNLSFQVRPGTVTGFLGPNGSGKSTTMRMILGLDAPTAGHATIGGRPFRQTPNAARQVGALLDAKAVHGGRSARAHLLSLAQLSGIPAQRVDEVLGVVGLQDVAHRRSKGFSLGMGQRLGIAAALLGDPQVLLFDEPVNGLDPEGILWVRNLMRQLAAEGRTVFVSSHLMSEMALTAEHLIVIGRGQLLADMAVKDFISANSADFARVRTPDGAPEQREKLTAALAEAGGQAAPEADGALRVTGLPLPRISELAHAADVRLWELSPHQASLEEAYMRMTQGAVDYRSTADQRAGLQPVAGYPPQGAAAPQGFVPGQPGAPGQVPPGMPGPPPNPYAPQDPYARPAPVPGGPVPPQQGHPYGAPTAYGAPHPYGQQPPAPVPAAPYAPAGPPAPPAPPAAPTDQPAPHTQDAR
>NZ_CP006871.1|WP_016577861.1|6642993_6643767_-|ABC-transporter-permease
MAVVGQVLRAEWVKIRSVRSTVWTLGTAVVVTVVLGVVICTLTRKDFDGMPEERRLAFDPTNMSFAGMGLGQLAMIVFGVLVVSNEYGTGMIRTSLAAVPQRGVFLFCKMLVATSLVFAVGLATSFAAFFAGQAALGGHRAHLGDPGVLRAVVGGALYMTMIALFSMAVATMLRSPMLSLGILMPFFFLISNILGNVSATRRIGRYLPDQAGSKIMQVVAPVNDETPYGPWGGFGIMAVWTVAALLVGYLLLDKRDA
>NZ_CP006871.1|WP_037636828.1|6643770_6644793_-|ATP-binding-cassette-domain-containing-protein
MIELMGLTKHYGDKVAVDGLTFTVRPGIVTGFLGPNGAGKSTTMRMVLGLDNPTAGAVRIYGRHYRQLKDPLRYVGALLDAKAMHGGRSAANHLLCLARSNGIPRTRVDEVLHLVGLTSVARKRSKGFSLGMGQRLGIAAALLGDPRILMFDEPVNGLDPEGIHWIRHLMKNLAAQGRTVFVSSHLMSEMALTAEHLVVIGQGRLLADTSMAEFIRQNSRSYVRLRSPDRERLLDVLHRAGVRAVAGRGGVLEVDGVPAERLGELAAAQQVVLHELSPQQASLEEAFMQLTAGAVEYHAHNGGRPGPGRGMPPRPVVPERALSGGAPPGGWGAGWQRKRS
>NZ_CP006871.1|WP_016577859.1|6644942_6645881_-|cellulose-binding-protein
MSDTSSPFGFELVRRGYDRGQVDDRITKLVADRDSALARITSLEKRIEELHLETQNAQAQVTDAEPSYAGLGARVEKILRLAEEEAKELREEARRAAEQHRELAESAAQQVRNDAEAFAVERKSKAEDEGARIVEKAKGEASTLRAEAQKDAQSKREEADALFEETRAKAAQAAADFETNLAKRREQSERDLASRQAKAEKRLAEIEHRAEQLRLEAEKLRTDAERRARQTVETAQRQAEDIVADANAKADRIRSESERELAALTNRRDSINAQLTNVREMLATLTGAAVAAAGAPGDDESVSRGVPAQQSR
>NZ_CP006871.1|WP_037682847.1|6645995_6650444_-|hypothetical-protein
MRGNERQERQRAETDHLSQFEAEMERLKTERDKAVQHADDLGYQVEVLRAKLHEARRNLASRPAYDNLSHQAEQLLRNAQIQADQLRSDAEREVREARAQTQRLLQEAAERQARLDADLHAEAVTRRQRLDEELNERRQTVESHVNENVAWAEQLRARTESQARRLMEETRAESEQALATARTEAQRLADRARERLGTAAEEARSEAESILRRARTDAERLLNAASSQAQEATDQAEQLRTTAGAESEESRRQAAELTRTAEARVQEADTALREARAEAEKLVEEAQQAAGKRLSATESENEQRSRTAKAEVARLVAEATKEAEALRADAEQLRADARAESERLLSEAQESARSKAAEDSAAQLAKAARAAEEMVTKASEDAKATTKAAAAEAERLRREAEAEADRLREQAHDTAEQLKGAAKNDTKEYRAKTAELQEEARRLRGEAEQLRADAVAEGERIRSEARREAVQQIEEAAGTAEELLSKAKSDAEETRSGAVAESERVRTEAIERAASLRRQAEEALERARTEGEQLLLEGTQAAEELTREAEESAERLRGEAEEAAEERRAEAQTELDRLRGEAEEKLAAAEESLREARSEAERLRRETQEEAARLKAEAAERRRSLQQQAEEEAERLRSEASKDASTARSEAEAAAARLRGEAAAEAERLKAEAQETADRVRAEAAAAAERTGTEAAEALAEAQEEAGRRRREAEQLLGEAREESHQERTTAREQSEELLASARTRVSEAQAEAERLVEEADRRAAELVAAAEQTAQQVRDAVAGLHEQANEEIAGLRSAAEHAAERTTTEAQQEADRVRSDAYAERERASQDAARVRAEAQEATDAANALAERTVAEAIDEGERLRSEAAGVLDGARRDANTARSEAAEQADRLVSEATAEAERLVAEATAKAEELRAEAAEVLDGARRDANTARSEAAEQADRLVSEATAEAERLVAEATAKAEKAVGDATAKAQQLRTDASDALASAEQDAARARAEARDDANRMRSEAAEQCDRLLTEARAEAERIVTEAAELTSSAQDDAERAVREGQEAAERLRAEGEQRAQRLVAEATEAAEGLRAEAGEALEGARSEAERVADEARSAANKTRADAATQADELVAEAAGEAERLRSEAAERSAEAERAADRARADAREQADRMLATATADADRLRAEAAETVTAAQEHATRTRAEAAKVREEAEAAAERQRAEAQAESDRLLDETRKDAAKRRGDAAEQADQLIAKAQEEALKTATGAEEQADMMVGAARKEADRIVREATSEGNARVEKARTDADTLLGEARRDATAIRDRSEELRVRVESDVEELHERARRESAEAMKNAGERVDKLIAQATAQQTEAEEKAEKLMADANSEASKVRIAAVKKAEGLIKEAENKKGAAVRDADKMRADAKEEAARIVAEGKRELEVLARRRKDINTEISRVQDVLEALESFEVPTQGGDGKEGAAKAAAGAGTTRSSGKQSEG
>NZ_CP006871.1|WP_016570488.1|6650651_6651092_-|methylmalonyl-CoA-epimerase
MLTRIDHIGIACFDLDKTVEFYRATYGFEVFHTEVNEEQGVREAMLKINETSDGGASYLQLLEPTREDSAVGKWLAKNGEGVHHIAFGTADVDGVAADVRSKGVRVLYDEPRRGSMGSRITFLHPKDCHGVLTELVTAAAPEATDH
>NZ_CP006871.1|WP_016570487.1|6651256_6652432_+|acetyl-CoA-C-acetyltransferase
MIVAGARTPMGRLLGSLRSFSGADLGGVAIKAALDRAGIGGDQVQYVIMGQVLQAGAGQIPARQAAVKAGIPMSVPALTVNKVCLSGLDAIALADQLIRAGEFDVVVAGGQESMTNAPHLLPKSREGFKYGAVEMLDAMAHDGLTDAFENIAMGESTEKHNTRLGLGRAEQDEVAARSHQRAAAAQKNGLFEAEITPVEIPQRKGDPVLFSKDEGIRGETTTETLGKLRPAFAKDGTITAGSSSQISDGAAAVVVMSKAKAEELGLEWIAEIGAHGNVAGPDNSLQSQPSNAINHALAKDGLSVQDLDLIEINEAFAAVAVQSMKDLGVSPEKVNVNGGAIALGHPIGMSGARIVLHLALELRRRGGGTGAAALCGGGGQGDALIIRVPGK
>NZ_CP006871.1|WP_016570486.1|6652530_6653490_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MVDVPQLVAQAREGRPRAVARLISLVEGAAPELREVMAALAPLTGGAYVVGLTGSPGVGKSTTTSALVTAYRKAGKRVGVLAVDPSSPFSGGALLGDRVRMSDHASDPGVYIRSMATRGHLGGLAWAAPQAIRVLDAAGCEVILVETVGVGQSEVEIASQADTSVVLLAPGMGDGIQAAKAGILEIGDVYVVNKADRDGADATARELNHMLGLGESRAPGDWRPPIVKTVAARGEGVDEVVEALEKHRAWMEERGVLARRRLARASREVETIAVTTLRSRIGDLSGDRHLGALAERIVAGETDPYRAADELVAGLTNGG
>NZ_CP006871.1|WP_016570485.1|6653515_6653992_-|MarR-family-transcriptional-regulator
MTTDSDTPWLTDQEQRAWRTHLDVSRLLMHQLERDLQPFGLTNNDYEILVNLSEAEDHRLRMSDLAASTLQSKSRLSHQITRMENGGLVRRESCESDRRGLYAVLTDEGWETMRRVAPHHVASVRRHFIDLFAPESLDSLESSLAPVADHLRRHRGNP
>NZ_CP006871.1|WP_016570484.1|6654115_6654889_-|Ser-or-Arg-related-nuclear-matrix-protein
MTGPVIHDVHTLPVDDNVNPYAFSVDLDGQWFLQKGKMIAYYGQIDFHGIGHGRLDHLIAGSFHSPLHAADWVVAEGRGKMLLADRSFDINSYDLDEGNLTIRSGNVLAFQPSLSLKQSIIPGFLTLIGTGKFVAASNGPVVFVEPPVRVDPQALVGWADCPSPCHHYDHQYLRGFLGGLRAHTGFGGASGEEHQFEFTGAGTVLLQSSEQLMPERATGALPAEEGVPGGGVPTPESGSQVPQLPGGLGGLQRRFGL

Crispr_ID: NZ_CP006871_8

• CRISPR_ID: NZ_CP006871_8
• CRISPR_location: 6673085-6673177
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP006871_8

Consensus_repeat	Method
CAAGCCGTCGGCGGACCCGTCCGC	CRISPRCasFinder

spacers of NZ_CP006871_8

>8.1|6673109|45|NZ_CP006871|CRISPRCasFinder
TTCACCCTCGCCGTCGCCGTCCGCCAGCAAGGACGCGAGCACCAC

CRISPR arrays and Neighbor proteins around NZ_CP006871_8

CRISPR arrays

The CRISPR arrays of NZ_CP006871_8

>merge|NZ_CP006871|8|6673085-6673177|CRISPRCasFinder
CAAGCCGTCGGCGGACCCGTCCGCTTCACCCTCGCCGTCGCCGTCCGCCAGCAAGGACGCGAGCACCACCAAGCCGTCGGCGGACCCGTCCGC

>NZ_CP006871|8|6|6673085-6673177|CRISPRCasFinder
CAAGCCGTCGGCGGACCCGTCCGC	TTCACCCTCGCCGTCGCCGTCCGCCAGCAAGGACGCGAGCACCAC
CAAGCCGTCGGCGGACCCGTCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_079164288.1|6673941_6674331_-|hypothetical-protein	unknown	unknown	gnl|CDD|180487
NZ_CP006871.1|WP_016571406.1|6664231_6664969_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP006871.1|WP_020930552.1|6668689_6669340_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379883
NZ_CP006871.1|WP_020930554.1|6683373_6684162_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NZ_CP006871.1|WP_016578698.1|6677172_6679266_-|phosphate-acetyltransferase	unknown	unknown	gnl|CDD|235537
NZ_CP006871.1|WP_020930555.1|6685543_6686224_-|response-regulator	unknown	unknown	gnl|CDD|226931
NZ_CP006871.1|WP_016578697.1|6675909_6677145_-|acetate-kinase	unknown	unknown	gnl|CDD|234680
NZ_CP006871.1|WP_016578696.1|6674357_6675785_-|pyruvate-kinase	unknown	unknown	gnl|CDD|180487
NZ_CP006871.1|WP_016578699.1|6679528_6680554_+|6-phosphofructokinase	unknown	unknown	gnl|CDD|235111
NZ_CP006871.1|WP_016571411.1|6671313_6671931_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016571407.1|6666474_6667635_+|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase	unknown	unknown	gnl|CDD|234825
NZ_CP006871.1|WP_044370983.1|6684380_6685091_-|DNA-binding-protein	unknown	unknown	gnl|CDD|376540
NZ_CP006871.1|WP_016571410.1|6669646_6670615_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|225660
NZ_CP006871.1|WP_016571408.1|6667631_6668663_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|275033
NZ_CP006871.1|WP_016571404.1|6660971_6662672_+|isobutyryl-CoA-mutase-A	unknown	unknown	gnl|CDD|239652
NZ_CP006871.1|WP_037682845.1|6662718_6664143_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP006871.1|WP_016570347.1|6686220_6687879_-|GHKL-domain-containing-protein	unknown	unknown	gnl|CDD|225827
NZ_CP006871.1|WP_016571412.1|6672166_6672727_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016578700.1|6680670_6683244_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226957
NZ_CP006871.1|WP_016571406.1|6665674_6666412_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_079164288.1|6673941_6674331_-|hypothetical-protein	gnl|CDD|180487	PRK06247, PRK06247, pyruvate kinase; Provisional.	1.63853e-29
NZ_CP006871.1|WP_016571406.1|6664231_6664969_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.72949e-90
NZ_CP006871.1|WP_020930552.1|6668689_6669340_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|379883	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal. This family of bacterial transcriptional repressors is characterized by the short approximately 50 amino acid stretch of residues constituting the helix-turn-helix DNA binding motif, around the YRFhY motif. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. Another target protein is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	6.52387e-15
NZ_CP006871.1|WP_020930554.1|6683373_6684162_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	5.55364e-107
NZ_CP006871.1|WP_016578698.1|6677172_6679266_-|phosphate-acetyltransferase	gnl|CDD|235537	PRK05632, PRK05632, phosphate acetyltransferase; Reviewed.	0
NZ_CP006871.1|WP_020930555.1|6685543_6686224_-|response-regulator	gnl|CDD|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	2.99296e-67
NZ_CP006871.1|WP_016578697.1|6675909_6677145_-|acetate-kinase	gnl|CDD|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP006871.1|WP_016578696.1|6674357_6675785_-|pyruvate-kinase	gnl|CDD|180487	PRK06247, PRK06247, pyruvate kinase; Provisional.	0
NZ_CP006871.1|WP_016578699.1|6679528_6680554_+|6-phosphofructokinase	gnl|CDD|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	4.2682e-175
NZ_CP006871.1|WP_016571407.1|6666474_6667635_+|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase	gnl|CDD|234825	PRK00726, murG, undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional.	3.16264e-112
NZ_CP006871.1|WP_044370983.1|6684380_6685091_-|DNA-binding-protein	gnl|CDD|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	0.000205697
NZ_CP006871.1|WP_016571410.1|6669646_6670615_+|tetratricopeptide-repeat-protein	gnl|CDD|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	8.88616e-61
NZ_CP006871.1|WP_016571408.1|6667631_6668663_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|275033	TIGR04180, NAD-dependent_epimerase/dehydratase, NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family. This clade within the NAD dependent epimerase/dehydratase superfamily (pfam01370) is characterized by inclusion of its members within a cassette of seven distinctive enzymes. These include four genes homologous to the elements of the neuraminic (sialic) acid biosynthesis cluster (NeuABCD), an aminotransferase and a nucleotidyltransferase in addition to the epimerase/dehydratase. Together it is very likely that these enzymes direct the biosynthesis of a nine-carbon sugar analagous to CMP-neuraminic acid. These seven genes form the core of the cassette, although they are often accompanied by additional genes that may further modify the product sugar. Although this cassette is widely distributed in bacteria, the family nomenclature arises from the instance in Leptospira interrogans serovar Lai, str. 56601, where it appears as the 30th gene in the 91-gene lipopolysaccharide biosynthesis cluster.	7.16252e-165
NZ_CP006871.1|WP_016571404.1|6660971_6662672_+|isobutyryl-CoA-mutase-A	gnl|CDD|239652	cd03680, MM_CoA_mutase_ICM_like, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM. ICM from S. cinnamonensis is comprised of a large and a small subunit. The holoenzyme appears to be an alpha2beta2 heterotetramer with up to 2 molecules of coenzyme B12 bound. The small subunit binds coenzyme B12. ICM catalyzes the reversible rearrangement of n-butyryl-CoA to isobutyryl-CoA, intermediates in fatty acid and valine catabolism, which in S. cinnamonensis can be converted to methylmalonyl-CoA and used in polyketide synthesis.	0
NZ_CP006871.1|WP_037682845.1|6662718_6664143_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.42918e-56
NZ_CP006871.1|WP_016570347.1|6686220_6687879_-|GHKL-domain-containing-protein	gnl|CDD|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	2.59085e-124
NZ_CP006871.1|WP_016578700.1|6680670_6683244_-|ABC-transporter-permease	gnl|CDD|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	2.41624e-27
NZ_CP006871.1|WP_016571406.1|6665674_6666412_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.72949e-90

Protein sequences

>NZ_CP006871.1|WP_016571412.1|6672166_6672727_+|hypothetical-protein
MSAERPQLNETLGRKRQAFREWRGQRPFWGGLLTLLAGAPIMYIPYANLTIGSLTVRMATTAGAGSLIIGVLLVVLGLTMWFQPVSRVFAGVAAILLSLVSLVVSNFGAFLIGFLLGLIGGALGVSWAPGKPVQGEDGSDEPDRVVGPVVATNPAPAVGGPGLGNGLDNLSGTSPTNGRNGRHRAG
>NZ_CP006871.1|WP_016571411.1|6671313_6671931_+|hypothetical-protein
MESLTRGGTRWKRFAVVMVPSVAATAAIGVALSQGALAASFSVSGQQFKVSTDRLDGTGFVQYGAVDAQKDGKNVPVAVSAFSTAKIRNLCQSVVVPVPVFGDVSMQLRAGGGETPVVAKNLYIDLDQLSADATFRNINIGVAAGSSTKGPGIKEGDKADPGSFAQEADTAVLTGVKQRAWATTAGTFKLSGLKMSVTKGKNECY
>NZ_CP006871.1|WP_016571410.1|6669646_6670615_+|tetratricopeptide-repeat-protein
MQPRNMSMSGVVDLAAVKAAGEAKQKAEQARAEAARTGAAPAGATRLVFDVDEAGFQEDVLQRSTEVPVVIDFWAEWCEPCKQLGPLLENLAAEYAGKFVLAKIDVDANQMLFQQFGVQGIPAVFAVVAGQPIPLFQGAVPEGQLRQVLDQLVQVAEQQFGIVGVPVDPAAAEQAEAAAPPPVGPYDAALTAAADALDAGDLDGAIRAYRNVLADDPTNPEAKLGLAQAELLKRVQGLNPQTVRQEAADRPTDVQAQITAADLDLVGGHVEDAFGRLVDAVQRTAGDDREAARVRLLELFEVIGADDPRVTKARTALARVLF
>NZ_CP006871.1|WP_020930552.1|6668689_6669340_-|TetR/AcrR-family-transcriptional-regulator
MVARMHQSAHPSKGRPGRPRSVETDHAILDATRAALVDVGWGGLTMGEVAARAGVAKTTLYRRWANKSELVVDAVAVLFDELELPDRGCLQSDIEGVVLQFGRLLARPETKTALMAVVAESTTDDALRERIRSAIVERQKRLVLLGRSRAQQRGELPPDAGGPEGERAAEHTVGLIFDVIAGAVVHRLLVSAEPVDTGWARQFTTLLLAGLAGLGH
>NZ_CP006871.1|WP_016571408.1|6667631_6668663_+|NAD-dependent-epimerase/dehydratase-family-protein
MTTSSTSSTNSTASRSWAGRKVLVTGAEGFIGSTLVDLLVAAGAEVRAFVHYKPYAEKGNLARYLEPGGPVEMLAGDVRDAGRVMDAVAGCDTVFHLAALIGIPYSYDSPGAYVQTNVMGTENVAEACRRHGVRRMVHTSTSEVYGTARTAPIGEDHPLQPQSPYSASKIGADMMALSHWHAFELPVTVVRPFNTYGPRQSARAVIPTILAQLHAGARQIKLGSLTPTRDFTYVTDTAAGFLALADCDRAVGQVVNLGSGQEITIGALAEALIAASGRDAEVVVDAARLRPSGSEVERLLSDNSRAREWASWQPEVTLKEGLARTSEWVAEHLHLFRADRYQV
>NZ_CP006871.1|WP_016571407.1|6666474_6667635_+|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase
MRTPLSVVIGAGGTGGHIYPGLALADALRRAVPDAEISFVGTDRGLETRLIPQAGYRLHTVDMIPFDPALGARRYLLPAALLRSGAQCRAILRDQRAQVAVGMGGYPSAPVIVGARMAGLPSLIHESNAVPGRANKFAARLTPHIALAFDRSRPHLAGGERAETVGMPLSGPLAALDRAALRPVARRALGVPEEARLVVVNGGSLGAARLTEAAVDLAGRYLTRTGLRLLIKTGPAALDAARAALEANGGAAVARAVPYLDRMDLAYAAADLVLCRAGSATVAELATIGMPAVLVPYPHAPGDHQTHNARVLSDAGAALLLPDAEVTGARLDALLTPLLADPARLAAMGAAADPGTHARAADLLAARTLALAGHPHHLVTTQKESA
>NZ_CP006871.1|WP_016571406.1|6665674_6666412_-|response-regulator-transcription-factor
MTAPPAPAPVPGTPPPVAARILVVDDEPEVRAAVADGLAVEGYAVRGAADGLAALSEIATWQPDALVLDVMMPVLDGLAVCRRLRALDDRTPILVLTALDSVSDRVDGLDAGADDYLVKPFALDELIARVRALLRRAAAGTADARLAFADLVVDPATRSGHRGGRPLEFSRTEYALLELLLQHPGQVLPRETILERVWGRDFGPDSNSLAVYVGYLRRKLEAGGEPRLVHTVHGVGYRLDRPEGA
>NZ_CP006871.1|WP_016571406.1|6664231_6664969_-|response-regulator-transcription-factor
MTAPPAPAPVPGTPPPVAARILVVDDEPEVRAAVADGLAVEGYAVRGAADGLAALSEIATWQPDALVLDVMMPVLDGLAVCRRLRALDDRTPILVLTALDSVSDRVDGLDAGADDYLVKPFALDELIARVRALLRRAAAGTADARLAFADLVVDPATRSGHRGGRPLEFSRTEYALLELLLQHPGQVLPRETILERVWGRDFGPDSNSLAVYVGYLRRKLEAGGEPRLVHTVHGVGYRLDRPEGA
>NZ_CP006871.1|WP_037682845.1|6662718_6664143_-|HAMP-domain-containing-histidine-kinase
MTGRRRLGGRWVRRRPLRTRLALAASAAVALVAVGVCAAAFLVLRVQMTRQLDLNLAQTATQLAQRTRNWGPTAGDTSCRYQAVPCVQIIPADPARDAHGRSPALPVSPATREVAAGRRAPYYTNLTVAGYPVRLYIVRLHGKDEALQVALRSDTVERGVRQAAWALAAVGGTGVLLAAALGYWVSRTGLAPVARLTATAERIATTRDPRHRIDLPTGPAAHEDEITRLATSFNTMLGELEQSVTAQRRLVADASHELRTPLTALRTNAELLARADRLTDEQRNRASGALARQLREVTTLVNDLIELARDEEPRPLLEQVRPAELLEHAVAAAREHWPEVGFTVRIAPGAADATRPGVPARLTRLLSNLLDNAAKFSPPGGPVETELDVVADALDLTVRDHGPGIATDDLPYVFDRFYRAQAARALPGSGLGLAMARQIARAHGAELTAERAPGGGALFRLRMPLTPPPEEGAG
>NZ_CP006871.1|WP_016571404.1|6660971_6662672_+|isobutyryl-CoA-mutase-A
MDADAIEEGRRRWQARYDSARKREADFTTLSGDPVEPVYGPRPGDAVEGFERIGWPGEYPFTRGLYPTGYRGRTWTIRQFAGFGNAQQTNERYKMILKAGGGGLSVAFDMPTLMGRDSDEPRSLGEVGHCGVAIDSAADMEVLFKDIPLGDVTTSMTISGPAVPVFCMYLVAAERQGVDPGVLNGTLQTDIFKEYIAQKEWLFQPEPHLRLIGDLMEHCAHGIPAYKPLSVSGYHIREAGATAAQELAYTLADGFGYVELGLSRGLDVDTFAPGLSFFFDAHVDFFEEIAKFRAARRIWARWMRDVYGARSEKAQWLRFHTQTAGVSLTAQQPYNNVVRTAVEALAAVLGGTNSLHTNALDETLALPSEQAAEIALRTQQVLMEETGVGNVADPLGGSWYVEALTDRIEADAEKIFAQITERGARAVPNGQHPVGPITSGILRGIEDGWFTGEIAESAFRYQQALEKGDKRVVGVNCHDGSVTGDLEILRVSHEVEREQVRVLAERKAARDDARVQATLKELLAAARSDRNMIEPMLAAVRAEATLGEICGALRDEWGTYTEPAGF
>NZ_CP006871.1|WP_079164288.1|6673941_6674331_-|hypothetical-protein
MADFLDGKALVAFTKSGDTARRLSRYRAAQPILAFTTDVATRNQLTLSWGVDSFVVPHVDNTDAMVDLVDAELLKLKRYSEGDTMIITAVFRCRTVGTGAGRVSPRWTPACRGCAGCRRTGPPGPASPC
>NZ_CP006871.1|WP_016578696.1|6674357_6675785_-|pyruvate-kinase
MRRSKIVCTLGPAVDSYEKLKTLIEAGMNVARFNMSHGTHSEHEERYHRLRKAAEETGRAVGVLADLQGPKIRLETFAEGPVELVRGDEFVITTEDVPGDKHICGTTYKGLPGDVSKGDPVLINDGNVALQVVEIDGPRVRTIVIEGGVISDHKGINLPGAAVNVPALSEKDIDDLKFALHMGCDMVALSFVRDAKDVQDVHRVMDEVGRRVPVIAKVEKPQAVANMQEVVMAFDAVMVARGDLAVEYPLEKVPMVQKRLVEMCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGQYPIETVKTMSKIVEAAEEELLSKGLQPLVPGKKPRTQGGAVARAACEMADFLDGKALVAFTKSGDTARRLSRYRAAQPILAFTTDVATRNQLTLSWGVDSFVVPHVDNTDAMVDLVDAELLKLKRYSEGDTMIITAGSPPGVPGTTNMVRVHHLGGQRA
>NZ_CP006871.1|WP_016578697.1|6675909_6677145_-|acetate-kinase
MTANATRVLVLNSGSSSVKYQLLDMEKAADGDSAGARLAVGLVERIGEGTSRLAHTPLAAGGATRETTGPIADHQAALKAVADELAADGLGLDSPELAAIGHRVVHGGLKFTAPTVIDAAVLKEIERLVPVAPLHNPANIIGIRTAQALRPDLPQVAVFDTAFHTTMPESAARYAIDVETADAHRIRRYGFHGTSHAYVSRRTAELLGKAPEEVNVIVLHLGNGASASAVRGGRCVDTSMGLTPLEGLVMGTRSGDIDPAVTFHLKRVAGMSADEIDELLNKKSGLLGLCGDNDMREIRRRIDEGDERAALAFDIYIHRLKKYLGAYTAVLGKVDAVAFTAGVGENAAPVRAAAVAGLEELGMAVDASLNAVRSDEPRLISPDYARVAVAVVPTDEELEIARQTYALVTAS
>NZ_CP006871.1|WP_016578698.1|6677172_6679266_-|phosphate-acetyltransferase
MTRSVYVTGIDRGDGRQVIELGVMELLTRHVDRVGVFRPLVHDGPDRLYELLRARYRLTQPADSVYGISYAEAAALQAERGTDELVSRLVDRFHAVAREYEYVLVLGSDYADTSLPDELALNARLANEFGAAVIPVVGGQGQDAESVRAEARNAHRAYTTLGCDVVALVVNRVAPEQRTAVVERLAARLPVPCYALPEEGSLSAPTVGQIVQALGAEILLGDDSGLARDARDFVFGGAMLPTFLKALTPGCMVITPGDRADLVIGSLAAHSAGAPPIAGVVLTLDERPGPDIMALAARLAPGTPVVSVPGGSFPTAAELFAVEGKLNAASPRKAETALGLFERHVDTGELTDRISVARSGRVTPMMFEHELIERSRSGRRRVVLPEGAEERVLRAADVLLRRDVCDLTLLGEEDAVRKRAADLAIDLADAQVIDPQTSPLRERFAELYATLRSHKGVSYELAYDVVADVSYFGTLMVQEGLADGMVSGAVHSTAATIRPAFEIIKTKPGAQIVSSVFFMCLADRVLVYGDCAVNPDPNAEQLADIAIQSATTAAQFGVEPRIAMLSYSTGTSGSGADVDKVRKATELVRERRPDLLVEGPIQYDAAVDAAVARTKLPDSEVAGKATVLIFPDLNTGNNTYKAVQRSAGAVAVGPVLQGLRKPVNDLSRGALVQDIVNTVAITAIQAQGAQPGAGPTA
>NZ_CP006871.1|WP_016578699.1|6679528_6680554_+|6-phosphofructokinase
MRIGVLTAGGDCPGLNAVIRSVVHRALAGHGDEVIGFEDGFKGLLDGRFRKLDLDAVSGILARGGTILGSARLERARLREACESAKDFSREYGIDVLIPIGGEGTLTAARMLADAGMPVVGVPKTIDNDISSTDRTFGFDTAVGVATEAIDRLKTTAESHQRVMVVEVMGRHAGWIALESGMAGGAHGICLPEREFDVNDLVKMVEERFARGKKFAVVCVAEGAHPLAGTMDYKKGAIDQFGHERFSGIGTALARELERRLGKEARPVILGHVQRGGTPTAYDRVLATRFGWHAVEAAHRGDFGKMTALRGTDIVMAPLADAITELKRVPESRMDEAESVF
>NZ_CP006871.1|WP_016578700.1|6680670_6683244_-|ABC-transporter-permease
MFTTALRNVLAHKARLLMTALAVLLGVAFVAGTLIFSDSVGEAIKNASAKNLKDVAVSVQATSPPGTGPEPAKDGKRATALDQRLADRIRALPGVTSVRSDVTGEATLAGRDGEPIGNGWQNRAANYQPDADGKDLRYPLVQGRGPASDGEIALAETTAKAAGVRVGDSVRFATDGPVLTKKLVGIVATDDPAVTAGGSLALFDTATAQKLYLHPGQFDELVVAAAPGTDQQALTAKVRALLPAERAEATSGSALAAEQSRLIADQNRALSSTLLTFAGIALFVGVFIIANTFTMLISQRSREIALLRAVGASRRQVVRSVLVEAALLGLVSSVVGFALGAGIAVGLRAALDANGAGFPNGPVVISPTTVLASLAVGVLVTVLAAWLPSRRAARIAPVEALSTVEAPPTPRSLVVRNVLGALIGGAGVAVMLWVSTLTSGDDLPIAMIGSMLTLTGAIILAPLLSRPLVSLAGLVTSRFFGVSGKLAKENALRNPRRTAATGSALMIGLTLITGMTVAGHSAQVAMDKMAGSGLIADYKVETNTYVGLDPKLSAKVAEVPGVAAMAPLRGTGFSTAPGPGPDSNFGFLRGTDVDQIGKVTRLSVVQGSLDAVKAGGIAISESGAKEHGWHAGDTVKVTFYDKKKAELKVGAVYADNEVLGASFAPTAVVDPHLDRLRNDELLVKTANGTSPALVKEIRKALGDSPLLKIQDRDDLRKETAGQIDTIVNMVYGLLAMAVIIAVVGVVNTLAMSVFERTREIGMLRAIGLARSGIKQMVRLESVVISLFGAVLGMVLGIFLAWAGGSLVGSSFPTYEMLLPWGRLGLFLLIALVVGVLAAVWPARRAARLNVLESIGAQ
>NZ_CP006871.1|WP_020930554.1|6683373_6684162_-|ABC-transporter-ATP-binding-protein
MPHAAVPRPAFPSRTTAAVAARATDLSKVYGQGETRVVALDSVDVEFGRARFTAIMGPSGSGKSTLMHCMAGLDSVTSGSARIGDVELAALNDKQLTRLRRDKIGFIFQAFNLLPTLTAQENITLPMDIAGRRVDQEWVGRVVETVGLSGRLSHRPAQLSGGQQQRVAVARALAAQPEIIFADEPTGNLDSRSGAEVLGFLRESVRAMDQTVVMVTHDPVAAAYADRVVFLADGRIVDELAEPTADSVLDRMRRFETAGRTS
>NZ_CP006871.1|WP_044370983.1|6684380_6685091_-|DNA-binding-protein
MAVNTHDGDARRPPFNAAAARRLREALGMTHAHVAYGIWAAYGIRLEPAAVASWELGESAPTEAELTALAGALWCAPAELLGAPGTLREFRLALGLAAADLALRVGMDQAAYERLEAGGRWTGTDRQAAALAAELRLPLPALIRFTGQEERLAELLISAATTRWQGYVRPVGKLAPLPKERLQQALQELHEEYHATMTASLSWTGGDASDEAGKAGRDFLDGIVVEFWRRVGEPAP
>NZ_CP006871.1|WP_020930555.1|6685543_6686224_-|response-regulator
MSAGTIRVLVVEDDPVAAAAHALYVGRVPGFAVSGTVHSGAGARRHLDQHPVDLVLLDLFLPDGHGLQLLRTLRAAGQSADIIAVTSARDLAMVREGVSLGVVQYVLKPFTFATLRDRLLRYAEFRATSGEASGQDEVDRALAALRAPQPAALPKGLTPATLRAVTEVLRAAADGLTATEAAADVGISRITARRYLEHLVAGGRAARAPQYGQVGRPELRYRWSGR
>NZ_CP006871.1|WP_016570347.1|6686220_6687879_-|GHKL-domain-containing-protein
MHLPRSRPPRRLRGPRSLAGQLFAMQVVLVAVVVLGCAVFAYVSAERQAEETARRQATAAATAVADSPAVVAAARTKDPTAALQPYSERLRRDAGVDFVVVMAPDGTRWTHPEPSAIGGKYLGHIGPALRGEVFPETHMGVLGPSVRVVAPVRDPERGGAITALVSSGITIATISEQLRDQVLALVGVAAAALALGGLGTYVVNARLRRHTHGMNTAELARMYDYHEAALHAVREGLLMLDGAGRVALINDGGRELLGLTGDAVGRPVDGLGLPEPLTAALLAAGPRVDELHLTGERVLVVNSSPVSGGQHRGSVVTLRDHTELQALSGELDSVRGFAEALRSQAHEAANRLHAVVSLIELGRAEEAVEFATAELELAQALTDRVVGAVAEPVLAALLLGKAAQANEHGVELVLTEDSRIDDGVIPPDLPARDLVTVLGNLIDNALDAAAPPQEHDAPPQVRVTARADGGELLLCVADNGPGVAAETTEEVFRRGWSTKEHAGGGARGLGLALVRQAVHRHGGTVGLARGPQGGARFTVRLPLRAAEGTGVR

Crispr_ID: NZ_CP006871_9

• CRISPR_ID: NZ_CP006871_9
• CRISPR_location: 6769612-6769695
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP006871_9

Consensus_repeat	Method
GGCCACTTCGAGGCAGTTGCCGCC	CRISPRCasFinder

spacers of NZ_CP006871_9

>9.1|6769636|36|NZ_CP006871|CRISPRCasFinder
CTCGCTGGCGCTGTAGCTCGACTTGCGCCAGGTGTA

CRISPR arrays and Neighbor proteins around NZ_CP006871_9

CRISPR arrays

The CRISPR arrays of NZ_CP006871_9

>merge|NZ_CP006871|9|6769612-6769695|CRISPRCasFinder
GGCCACTTCGAGGCAGTTGCCGCCCTCGCTGGCGCTGTAGCTCGACTTGCGCCAGGTGTAGGCGACTTCGAGGCAGTTGCCGCC

>NZ_CP006871|9|7|6769612-6769695|CRISPRCasFinder
GGCCACTTCGAGGCAGTTGCCGCC	CTCGCTGGCGCTGTAGCTCGACTTGCGCCAGGTGTA
GGCGACTTCGAGGCAGTTGCCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_020930690.1|6780599_6781775_-|glucose-sorbosone-dehydrogenase	unknown	unknown	gnl|CDD|369642
NZ_CP006871.1|WP_016573602.1|6768481_6769486_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381302
NZ_CP006871.1|WP_037635631.1|6771252_6773370_+|phospholipase-C,-phosphocholine-specific	unknown	unknown	gnl|CDD|274561
NZ_CP006871.1|WP_016573610.1|6777215_6780314_+|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|274846
NZ_CP006871.1|WP_016573601.1|6767554_6768460_+|TIGR03620-family-F420-dependent-LLM-class-oxidoreductase	unknown	unknown	gnl|CDD|274681
NZ_CP006871.1|WP_016571830.1|6758555_6760772_+|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NZ_CP006871.1|WP_016573611.1|6780328_6780523_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016573608.1|6775983_6776670_+|hypothetical-protein	unknown	unknown	gnl|CDD|225962
NZ_CP006871.1|WP_016573604.1|6769736_6770558_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP006871.1|WP_020930688.1|6757510_6758524_+|vitamin-B12-independent-methionine-synthase	unknown	unknown	gnl|CDD|239426
NZ_CP006871.1|WP_016573597.1|6763760_6764057_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl|CDD|178810
NZ_CP006871.1|WP_016571829.1|6760928_6763037_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NZ_CP006871.1|WP_020930689.1|6773697_6775893_+|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NZ_CP006871.1|WP_016573599.1|6765590_6765833_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016573609.1|6776924_6777113_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016573598.1|6764062_6765556_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl|CDD|234572
NZ_CP006871.1|WP_016573600.1|6765864_6767373_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl|CDD|235489
NZ_CP006871.1|WP_016575315.1|6781941_6782982_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381302
NZ_CP006871.1|WP_016573605.1|6770670_6771105_+|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NZ_CP006871.1|WP_016571832.1|6755999_6757400_+|MFS-transporter	unknown	unknown	gnl|CDD|129794

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_016573602.1|6768481_6769486_-|aldo/keto-reductase	gnl|CDD|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	7.55535e-163
NZ_CP006871.1|WP_037635631.1|6771252_6773370_+|phospholipase-C,-phosphocholine-specific	gnl|CDD|274561	TIGR03396, PC_PLC, phospholipase C, phosphocholine-specific, Pseudomonas-type. Members of this protein family are bacterial, phosphatidylcholine-hydrolyzing phospholipase C enzymes, with a characteristic domain architecture as found in hemolytyic (PlcH) and nonhemolytic (PlcN) secreted enzymes of Pseudomonas aeruginosa. PlcH hydrolyzes phosphatidylcholine to diacylglycerol and phosphocholine, but unlike PlcN can also hydrolyze sphingomyelin to ceramide ((N-acylsphingosine)) and phosphocholine. Members of this family share the twin-arginine signal sequence for Sec-independent transport across the plasma membrane. PlcH is secreted as a heterodimer with a small chaperone, PlcR, encoded immediately downstream. [Cellular processes, Pathogenesis].	0
NZ_CP006871.1|WP_016573610.1|6777215_6780314_+|LuxR-family-transcriptional-regulator	gnl|CDD|274846	TIGR03903, TOMM_kin_cyc, TOMM system kinase/cyclase fusion protein. This model represents proteins of 1350 in length, in multiple species of Burkholderia, in Acidovorax avenae subsp. citrulli AAC00-1 and Delftia acidovorans SPH-1, and in multiple copies in Sorangium cellulosum, in genomic neighborhoods that include a cyclodehydratase/docking scaffold fusion protein (TIGR03882) and a member of the thiazole/oxazole modified metabolite (TOMM) precursor family TIGR03795. It has a kinase domain in the N-terminal 300 amino acids, followed by a cyclase homology domain, followed by regions without named domain definitions. It is a probable bacteriocin-like metabolite biosynthesis protein. [Cellular processes, Toxin production and resistance].	7.51082e-39
NZ_CP006871.1|WP_016573601.1|6767554_6768460_+|TIGR03620-family-F420-dependent-LLM-class-oxidoreductase	gnl|CDD|274681	TIGR03620, F420_MSMEG_4141, probable F420-dependent oxidoreductase, MSMEG_4141 family. Members of this protein family, related to F420-dependent oxidoreductases within the larger family of a bacterial luciferase (an FMN-dependent enzyme), occurs only within the small subset of species that synthesize F420. Most such proteins are from members of the Actinobacteria, but at least one species, Sphingomonas wittichii, belongs to the Alphaproteobacteria. [Unknown function, Enzymes of unknown specificity].	6.17397e-106
NZ_CP006871.1|WP_016571830.1|6758555_6760772_+|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP006871.1|WP_016573608.1|6775983_6776670_+|hypothetical-protein	gnl|CDD|225962	COG3428, COG3428, Predicted membrane protein [Function unknown].	0.000782158
NZ_CP006871.1|WP_016573604.1|6769736_6770558_-|XRE-family-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.29681e-08
NZ_CP006871.1|WP_020930688.1|6757510_6758524_+|vitamin-B12-independent-methionine-synthase	gnl|CDD|239426	cd03310, CIMS_like, CIMS - Cobalamine-independent methonine synthase, or MetE. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme catalyses the last step in the production of methionine by transferring a methyl group from 5-methyltetrahydrofolate to L-homocysteine without using an intermediate methyl carrier. The active enzyme has a dual (beta-alpha)8-barrel structure, and this model covers both the N-and C-terminal barrel, and some single-barrel sequences, mostly from Archaea. It is assumed that the homologous N-terminal barrel has evolved from the C-terminus via gene duplication and has subsequently lost binding sites, and it seems as if the two barrels forming the active enzyme may sometimes reside on different polypeptides. The C-terminal domain incorporates the Zinc ion, which binds and activates homocysteine. Side chains from both barrels contribute to the binding of the folate substrate.	1.72018e-72
NZ_CP006871.1|WP_016573597.1|6763760_6764057_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl|CDD|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	6.70928e-39
NZ_CP006871.1|WP_016571829.1|6760928_6763037_+|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	3.79739e-104
NZ_CP006871.1|WP_020930689.1|6773697_6775893_+|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	4.34375e-91
NZ_CP006871.1|WP_020930690.1|6780599_6781775_-|glucose-sorbosone-dehydrogenase	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	7.48718e-91
NZ_CP006871.1|WP_016573605.1|6770670_6771105_+|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	2.03014e-21
NZ_CP006871.1|WP_016573600.1|6765864_6767373_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl|CDD|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NZ_CP006871.1|WP_016575315.1|6781941_6782982_-|aldo/keto-reductase	gnl|CDD|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	1.23946e-125
NZ_CP006871.1|WP_016573598.1|6764062_6765556_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl|CDD|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NZ_CP006871.1|WP_016571832.1|6755999_6757400_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	8.27514e-59

Protein sequences

>NZ_CP006871.1|WP_016573602.1|6768481_6769486_-|aldo/keto-reductase
MRRRRLGAHGPVVSALGLGCMGMSTSYGVPDDAESVRTLDRAVELGVTLLDTADAYGRGANEEFLGRWWGSRPGSVRDGLVVSTKFGLRHDAATGRVNAVDASAAWVRTACHASLRRLATDRIDLYYLHRRDPAVPIEETVGAMAELVAEGSVRHLGLSEVSPETLRRAHAVHPISAVQLEHSLFTRDVLEGEMLAACRELGVGVVAYAPLGRGMLTGALASRDDLTADDARRRWPRFADENIARNLALVRAIRATADSLGCTPAQAVLAWLLAQGEDVVPIPGTKHRTYLEENAAAAGLALDPEQADRLRAAVPDGAVAGERYPLAALARLGH
>NZ_CP006871.1|WP_016573601.1|6767554_6768460_+|TIGR03620-family-F420-dependent-LLM-class-oxidoreductase
MDQHALASRIGRVGVWHGGLGRVPAATARRAAVEIEQLGYGALWFGEGPASKEAFSHAGLLLAATGRITVATGIANIWGRDAAAANSAARTLAEAYDGRFLLGLGASHAPIVNVRGHTYAKPLAAMRDYLDAMDGASYEGPTSEPAPARVLAALGPKMLELARDRAAGAHPYFVPVEHTARAREVLGTGPLLAPELAVLLETDPAQARALAREQYVRHYLELPNYVGNLRRFGFEDDDFAGGGSDRLIDALVAWGDVDAIRRRVRAHLDAGADHVAVQPLAADRGLGLDQLRALAPALLAD
>NZ_CP006871.1|WP_016573600.1|6765864_6767373_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MTVTDLVPYEDALATYDPVMGLEVHVELGTHTKMFCGCATTLGAEPNSQTCPTCLGLPGSLPVVNATGVESAIKIGLALNCTIAEWCRFARKNYFYPDMPKNFQTSQYDEPIAFDGYLDVQLEDGEVFRVQIERAHMEEDTGKSTHIGGATGRIHGAQHSLLDYNRAGIPLIEIVTKPIEGAGERAPEVAKAYVAELRELIKALGVSEARMEMGQMRCDVNLSLRPLGTEKFGTRSETKNVNSLRSVERAARYEIQRHAAVLSSGGTIIQETRHFHEDDGSTTSGRVKEEAEDYRYFPEPDLVPVAPAREWVEELRATLPELPRVRRNRLREEWGVSALDMQSILNAGAVDLIVATTDAGADAASARKWWMGELARRANEDGVELGALPITAEQVARVAALVAEGSLNDKLARQAIEGVLAGEGDPDAVVEKRGLKVVSDEGALGTAVDEAIAANAAIADKIRGGKVAAAGALVGAVMKATRGQADAARVRELILEKLGVEG
>NZ_CP006871.1|WP_016573599.1|6765590_6765833_+|hypothetical-protein
MSGKLAKAKNFKKSKPGTYLSIGTTLFGAVSVVKQAKKAKGEHDTLQLVDAVVSAAAIVTGVALLVRELRRLNDDDVLAG
>NZ_CP006871.1|WP_016573598.1|6764062_6765556_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MADLIKLTAAEIAAKIAAGEVTAVEVTEAHLARIEAVDEKVHAFLHVDREGALAQARAIDDKRARGEKLGPLAGVPLALKDIFTTQDMPTTVGSKILEGWMAPYDATLTKKLKDADVVILGKTNMDEFAMGSSTENSAYGPTGNPWDLTKIPGGSGGGSSAALASFQAPLAIGTDTGGSIRQPAAVTGTVGVKPTYGGVSRYGMVAFSSSLDQGGPCARTVLDAALLHEAIAGHDPLDSTSIDAPVPAVVEAARNGSVDGMRVGVVKQFRGEGYQAGVLQRFDESVALLTELGAEIVELDCPSFDLALAAYYLIAPSECSSNLARFDAMRYGLRVGDDGTKSAEEVTALTREAGFGPEVKRRIMLGTYALSSGYYDAYYGSAQKVRTLITRDFERAFEQVDVIISPTTPTTAFPIGERTDDPMAMYLADVCTIPANLAGNAAMSLPCGLAPEDGLPVGLQIIAPALADDRLYKVGAAVESALTEKWGHPLIEEAPAL
>NZ_CP006871.1|WP_016573597.1|6763760_6764057_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MPGITREEVAHLARLARLELKDEELDHFAGQLDDIIGAVARVSEVAGQDVPPTSHPLPLTNVMRPDEVRPSLTPEQALSGAPAQEQQRFKVPQILGEE
>NZ_CP006871.1|WP_016571829.1|6760928_6763037_+|EAL-domain-containing-protein
MKPTDSAAPASRLRRLVVPALPAALVMAAGVTLAAGVLYTLGGGEPLFPSGPVGWALAVLTGVLVGHLVALGRDRWWGGTGSGAALALAVLLLYGWVPAVLVSLSVVILVGAARRQRWRQALVHGAVDVLGIGAAALGLAVCGVHPGVRQPWTPEAWDLSVLPEVVVTAGGYLLVSRGLLWCSRLPLDGGLPAIARTAVVRQALVGVALLGISPLIAVCAVGAPLLLPLFAVPLIALDSTLWIARARAEEQLRDPLTGLPNRQWLLERTWTALDEAERAGTRAALVLIDLDRFRSVNDTLGHLAGDRLLLQIADRLRHALPRGAEAARLGGDEFAVLLPATDSLTSSQRVARNLVAALSSPLDLDGLTLVLEASAGVAVYPEHALDAEGLLRRADVAMYQAKRDRSGVELYEAKRDGNTPDRLGLLGDLRRALDAGDVELHYQPKVRFDGHVSGLEALVRWVHPDRGRVPPDEFIAIAESSGLMPRLTEYVLETALAQVARWRAMGLEVPVAVNVSPRDVHSPGFAGAVAARLARHRVPPGALQLEITEHVLLEDPQRAADTLAGLTAHGVKMSLDDFGTGYSSLVHLRRLPVSELKIDRSFVARLAVDTEDAEIVRCTLDLAHSLGLLVVAEGVEDDETWERLRDLGCDAVQGWLVAAAMPPDETTAWLRARGEHGWRRASETTALAAEKAAERPSGQVVN
>NZ_CP006871.1|WP_016571830.1|6758555_6760772_+|NAD-dependent-DNA-ligase-LigA
MAGEQHAAASEVPAAAREEHAQLAEQIEEHRFRYYVKDAPVVSDTEFDKLLRALEALEETHPGLRTPDSPTQKVAGSYATEFTEVAHRERMLSLDNAFDDEELSAWAERIAGELGGDPKGAGYHFLCELKVDGLAVNLTYEHGRLTRAATRGDGRTGEDITPNVRTIAEIPHRLTGDRVPALVEVRGEVYFPMEKFLELNERLVADGKPPFANPRNAAAGSLRQKDPKVTATRPLHMVVHGLGARDGLEIDRLSEAYDLLQEWGLPTASHNRVVDSLAAVREFIAHYGDPETRRTAVEHEIDGVVVKLDEIRLQGRLGATSRAPRWAIAWKYPPEEVNTKLVDVRVGVGRTGRVTPYAVVEPITVAGSEVEFATLHNQDVVKAKGVLIGDTVVIRKAGDVIPEILGPVVDLRDGTEREFVMPAECPECGSALQPAKEGDIDLRCPNARSCPAQIRERLFYLAGRKCLDIENFGYVAATALSQPLEPAEPPLTDEGGLFDLSVERLLPIKSHVLDPDTGLPKRDPKTGEEKVVTFFANQKGEPKKNTLAMLENIQAAKERPLARILTGLSIRHVGPVAAQALAREFRSIDRIRDASEEELAAVDGVGGTIAASLKQWFAVDWHQEIIERWRAAGVRMEEEQTGDAGPRPLEGVTVVVTGTLQSHTRDGAKEALQALGAKVTGSVSKKTGFVVVGDNPGSKYDKAMQLKVPVLDDDGFAVLLEQGPEAARAVAVTPPEEE
>NZ_CP006871.1|WP_020930688.1|6757510_6758524_+|vitamin-B12-independent-methionine-synthase
MSENTRHKWAAGAATGIGSMPGGDAREAAKTVTGSLEDFPHLPELPARGPGADMIGRTLGLLVELYAHVEPSGWRISDRPGRDTRRSRSWLGEDLDALEEFTQGYTGPLKVSAVGPWTLAAALELRNGEVALGDPGACRDLTESLAEGLRGHLAEVRRRVPGAEVVLQLDEPSLTAVLQGRVRTASGYRTHRAVDRAVVEGALRDLVGVADGAPVVVHSCAPEVPFALLRRAGATGISFDAALLTEREDEALGEAVEGGTALFAGVVPGVDGRLSDPAGSVMGVRTLWRRLGLAPGLLAESVVVTPSCGLAGASPAYAREVLAHCVRAARSLADNPE
>NZ_CP006871.1|WP_016571832.1|6755999_6757400_+|MFS-transporter
MITETAAPRGTASTPTRPAPARGGVQLVVLALGFVMASLDTGIMNVAAHDLQARLGLTMSGLTWVVDGYVLSFAALLLLAGSLAKRFGARRTYLAGLAVFTVASLLGAAAPGGGALVAARLAQGAGAALFMPSSLSLLMNAFPEPARRAKVLGIWSAIVSTSVGLAPTLGGLLVGTLGWRSIFLVNLPIGILGLLLTRRVITPVPGTGAPLGGSGHVLGLLALGALSYALIEGPATGWTAPAVLAAFTVTVLAAAGFVLRERTARTPVLPVALFADSRFSAANAVGFLFNFAFYGALFVLGLFLQTGRGASAVTAGLQMLPAVLVLPLGNVLYTRIAPRTGNRTALTASLAFSAAGYLLLFLVLSPSLPYGVIAAVLAVANLASGISSPAMTGVLMEAAGREHADIGSATLNANRQVGSLVGIAGMGAVLTGAGGAYQGTGYAFALTALALAAAALLGRLGLRRWS
>NZ_CP006871.1|WP_016573604.1|6769736_6770558_-|XRE-family-transcriptional-regulator
MHQANKPKRITSWHVIGAQLSHFRKAARLTQPALAEAVGVHEDTIGSIEQGRRALKIDLAEAFDEILGTKGALAVAVEKVPDKERFPAFVQDFVEYEADAISLLSYENHVMPGLLQTPDYAQAVFSCLFPPISEADAAERLSARLDRQQLLQRDPPPVLNFILEEVVLRRPIGDAEVLREQIRHLRSCAELPFVGLQIMSTSRRKHAGLDGPLVLLETPDHGQLAYVEGQRVSFLVDDPDEVSVLQQKYGMLRSQALTPEDSVSLLDQLAGEA
>NZ_CP006871.1|WP_016573605.1|6770670_6771105_+|ATP-binding-protein
MQEEIQAVRVRTAFYRRERRSVSLAREFARSALADWDRKRGADEVVLCVSELATNAVLHGVPPGRGYRLWLALGAEDGVLRVEVHDSGDGEPRVPERGGAEDAEWGRGLLLVSALADAWGVEERVPGKIVWCEWRPAGGARGLP
>NZ_CP006871.1|WP_037635631.1|6771252_6773370_+|phospholipase-C,-phosphocholine-specific
MAPEVSRRRVLGVGAAAAGAAVAGSLLPPSLQQALAQDAAHPAWHRGGGLRDIKHVVVLMQENRSFDHYFGMLRGVRGFGDRNAVELRGGRGVFEQPGPLGVRHVLPFPVREAAAAQKKDLQYIGNLDHSWAGGHRAWNDGWMDNWIAAKSSATMAHYDRQDVPLHYELADTFTVCDAYHSSIHSSTSPNRNHLVSGWTGFEPGSGERAVGNDAYDEDKHTGYTWTTYPERLQEAGRTWQVYQEWDNFTDNNLEFYASFKAVAHKALAKVDGVHNMTAYYGKLAGAGDAERTRLAGLLEEGVRSLSRAERSLFERALRRGEPHSTAAAFAADVAGGKLPEVSYIVPSAADSEHPGSSSPIESATLVYKVLDALGSHPEVWRHTALFLTYDENDGFFDHVPPPVPPAGTAGEFWDGKPVGLGMRVPMLVISPWTVGGYACSQVFDHTSITRFLERWTGVEEPNISAWRRTVCGDLTTAFDFSRGRRQPAVHQPGPIPAFSGRWRPLPPLHQALPQQEHGSRPARALPYQPDADGGFEPDAGTFRLAVRNAGSASAHLALYPYAEEFDVPQHRDVRTAAEWAVPVKGGAYRFTVTGPNGFRREFAGSAKGAAAGVRISSRIDAARRELHLTLVNPGATDLTVTLAPLAYADASPRTLTVRAGATRTVAHAAGDAHGWYDLELTAAEDASFRRRLMGHVENGKESVTG
>NZ_CP006871.1|WP_020930689.1|6773697_6775893_+|MMPL-family-transporter
MTALARWCLRRRLLVILLWLAALTGTAVAAGVAGSAYSTDYAVPGTESGQAGALLAKAFPDRAGDADTVVWHTPDGTVHATAVRTTMTRTLAKVARLPGVADVQGPYGPGGAGQISHDGRTAYATVTFRSSPDDLPEAQARAVVSTARAAAGKGLQVESGGSGAALTQTPHERLPELIGLAVAAVVLFLAFGSLAATLLPLVTALAAVGTAASGISLLGHVMTVADFAPMLGMLIGLGVGIDYALFIVTRHRKGLRAGLGVQESAERALAVSGRAVVFAGATVCIALLGMLTLRLDFLNGVALAASLTVVLTVAAAVTLLPALLGVIGTRALGRRERRRLAAEGPRPDPGTGPAVRWAGFVERHPRLLGAVAAAVMLTLALPTLGLRLGTSDQGNDPATATTRKAYDLLADGFGPGFNGPLTLVGSLDGATDRLAFDELPHTLRDTPGVARVSGPEFGAGHATGVITVVPDSAPQSERTSDLVDRLRTTVLPAAADGTTLKVRVGGVTAGYDDFAAVIVGKLPLFVGAVIGLGSVLLLLAFRSIGIPLKAALMNLAAVAASFGIVVAVFQWGWGTEALGLGSAGPIEPFLPVIMVSVLFGLSMDYQVFLVSRMYEEWRRTGDNRRSVRVGLAETSRVINSAAVIMIAVFGAFVLSGDRIIAMFGIGLAAAVALDAFVLRTLLVPALMHLLGGANWWLPAWLDRRLPRLSIEPPDEPTPAAPRMDGRPRVEV
>NZ_CP006871.1|WP_016573608.1|6775983_6776670_+|hypothetical-protein
MGTTTDKRTDDATNDDAAATVVKTTAVEGDGAPETTTDGTEETGKAKGEAGKAPAGGEGSDTAPATTTDADADAASDTDAESDADADADAEDATPEEPAAAGAAAGAGAVVAAGLGLASVTGTWLSTLLAERQTLLGQIKLQSGKATDQIAAVYGAPWHTTALVNGVFAVLAMLVAAVVLTGRRPAWVRAVAWGGLVLGLLGLVISAGMYLDLFASMPSLPKGAGGGA
>NZ_CP006871.1|WP_016573609.1|6776924_6777113_+|hypothetical-protein
MYASELEIRIRYEELRREADRRRLVREATQGARGAADLASDDPEGRVRPSRARRWRVRRAAA
>NZ_CP006871.1|WP_016573610.1|6777215_6780314_+|LuxR-family-transcriptional-regulator
MLGTVESRPISPVFVGRAPELTELGDALARAGASREPQALLIGGEAGVGKTRLIEEFCETARGSGAQVALGGCIEIGSEGLPFAPFSSILHTLNAHLRDELAAAVAGQEGELARILPELGETAGEIRDEEIGRARLFELTARLLERLAAHRTLVIVVEDLHWADRSTRELLAYLLRALHDAGIVLIATYRSDDIHRRHPLRPFLAEIDRMRTVRRIELGRFNRDEVRSQIAGIRGSEPAEDTVDRVFKRSEGNAFFVEELARGLADGCLYGLSDPLRDLLLVRVEALPEDAQRVVRIAAEAGSTVEHELLAAVCQMPEDDLIEALRAAVGSNTLVPTQDGTGYRFRHALVREAVVDDLLPGERTRLNRRYAQALEADPGLVRAEVGATRLASYWYKAHDAAKALPAVLAASVQARRRHAYAEQLRLLDRALELWDDAPPEVRRGVRPLDYAEGYPACGCDDDALRFLDLLAEIAVAARLSGDSERAFMITKRALRRLRTENDPLRTAWFLMQRSRLCQGTGRGDGWEDLGRAQELMRGLPPSSVHATVTAAVASWQMLHEPGPGTFTTAERAVELARLVGDEEAELNSRVTLAGLSVDAGDVEAGLTEFRTALDRAVERGYFAVIGRGHVNLPGTLEGVGRSREAVEVTDQGTELTTRYGLKNSTSWVLSNRSESLQSLGRWPEAGQAATEARRLAQNSLALALAASRLTVLALDTGDLTAAERELAFAQEHYGTHDPQPQHALPMVRHALRLAARQGRILDARTLLVRSALDAGFAPGLHRYAWPLLWSAVTAEADARGLPAADPGRPEILARIRDAAKRLARLSPVWDAYGTAVEAELRRAEGRDSPDAWAEAVAAFTPVERPHELAWCCRRWAESLLHGTERATAGLDGRTPREVAVLLLGQAHTAAVDLGARPLVGELELLAQRARIPLAGRPAPGTARAAAGAPPPAPAESLGLTPRERDVLRLVADGRSNRQIADTLFISPKTASVHVSNILAKLGVSGRGEAGAVAHRLRLFAEPAPEKDPAPTA
>NZ_CP006871.1|WP_016573611.1|6780328_6780523_-|hypothetical-protein
MFNVVEELFAPGRKHTDEERQRMSLVLDDVGDGEPGTGPIDLASGVVVVRSRPQPPAPEGGAGG
>NZ_CP006871.1|WP_020930690.1|6780599_6781775_-|glucose-sorbosone-dehydrogenase
MQRRSHKAVLAAACLLLVAGCSSGGGPAAGGAGSVGPAHRPGSPAPSPSASAVVPPAKGTVRVTGTLATGLKSPWGVAVLPGGDLLVGERDTGRIVRVAAHGGKVTEVGSVPGAAPGGEGGLLGLAVAPSFGTDHQVYAYFTTASDNRIARMIYDERRDPGNQLGAPNTVFKGIPKGRFHNGGRLAFGPDRMLYASTGETGDKALAQDKKSTAGKILRMTPDGEPEHGNPEPDSVVYDYGHRNVEGLAWDADRRLWASEFGQDAWDELNLIEPGRNYGWPQVEGKRKGGAVPPGYADPVLVWKPADASPSGLAYAKGSLWMASLRGERLWRIPLDGTKPVAAPQAFLTGAYGRLRTVVAADDGALWLVTSNTDGRGRPRSGDDRILRLVVS
>NZ_CP006871.1|WP_016575315.1|6781941_6782982_-|aldo/keto-reductase
MERRTIGAAALEVGAIGLGCMPMSWGYSESQRSGEGSVRALHAALDRGCSLLDTADMYGPFTNELLVGRVLKERRQDAFVSTKCGLLAGDQHIVANGRPGYIKRACDASLRRLQTDHIDLYQLHRADPEVPVEETWGAMAELVAAGKVRALGLCAVGARAARTPRALRDGRLVPGGRGLRGSGLHAGTLRQLERVQQVFPVSSVQAELSVWSPEALVELLPWCESRGVGLLAAMPLGNGFLTGTLTPGQGFEPEDIRARHPRFTAEMMAANQPVVAGLRRVGARYGATPGQVALAWVLAQGSHVVPVPGTKKERWVAQNANAAELALAPEDLREIAALPRARESWY

Crispr_ID: NZ_CP006871_10

• CRISPR_ID: NZ_CP006871_10
• CRISPR_location: 7378567-7378667
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP006871_10

Consensus_repeat	Method
CCGCTGCGCGGGGCGTCGTCGTACGT	CRISPRCasFinder

spacers of NZ_CP006871_10

>10.1|7378593|49|NZ_CP006871|CRISPRCasFinder
CTCCGGCGTTCCCGCCGTGGGGGTTTCTGTTTGCGCCTGCGGCGCGTTG

CRISPR arrays and Neighbor proteins around NZ_CP006871_10

CRISPR arrays

The CRISPR arrays of NZ_CP006871_10

>merge|NZ_CP006871|10|7378567-7378667|CRISPRCasFinder
CCGCTGCGCGGGGCGTCGTCGTACGTCTCCGGCGTTCCCGCCGTGGGGGTTTCTGTTTGCGCCTGCGGCGCGTTGCCGCTGCGCGGGGCGTCGTCGTACGT

>NZ_CP006871|10|8|7378567-7378667|CRISPRCasFinder
CCGCTGCGCGGGGCGTCGTCGTACGT	CTCCGGCGTTCCCGCCGTGGGGGTTTCTGTTTGCGCCTGCGGCGCGTTG
CCGCTGCGCGGGGCGTCGTCGTACGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_037683385.1|7379215_7381141_-|beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|369423
NZ_CP006871.1|WP_016573510.1|7376070_7377411_+|allantoinase-AllB	unknown	unknown	gnl|CDD|238640
NZ_CP006871.1|WP_016577436.1|7381293_7381488_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016578997.1|7371364_7371595_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016576300.1|7383642_7384311_+|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl|CDD|180618
NZ_CP006871.1|WP_106966072.1|7367413_7368463_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP006871.1|WP_020930886.1|7368642_7370283_-|malate-synthase-A	unknown	unknown	gnl|CDD|236432
NZ_CP006871.1|WP_016576298.1|7385330_7386224_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|182137
NZ_CP006871.1|WP_016577434.1|7382260_7382644_-|VOC-family-virulence-protein	unknown	unknown	gnl|CDD|319916
NZ_CP006871.1|WP_078487227.1|7386210_7387641_+|MFS-transporter	unknown	unknown	gnl|CDD|369468
NZ_CP006871.1|WP_016578998.1|7370652_7371231_-|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|133025
NZ_CP006871.1|WP_016578995.1|7372426_7373230_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP006871.1|WP_020930890.1|7377407_7378538_+|allantoicase	unknown	unknown	gnl|CDD|237319
NZ_CP006871.1|WP_016578994.1|7373490_7374297_+|hydantoin-racemase	unknown	unknown	gnl|CDD|226611
NZ_CP006871.1|WP_016576299.1|7384445_7385282_+|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|270231
NZ_CP006871.1|WP_106966070.1|7382642_7382873_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_020930888.1|7374339_7375893_+|NCS1-family-nucleobase:cation-symporter-1	unknown	unknown	gnl|CDD|271404
NZ_CP006871.1|WP_016577435.1|7381545_7382178_-|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380339
NZ_CP006871.1|WP_016578996.1|7372107_7372395_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_037636072.1|7382869_7383301_+|ribonuclease	unknown	unknown	gnl|CDD|238340

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_037683385.1|7379215_7381141_-|beta-N-acetylhexosaminidase	gnl|CDD|369423	pfam07555, NAGidase, beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.	1.00323e-157
NZ_CP006871.1|WP_016573510.1|7376070_7377411_+|allantoinase-AllB	gnl|CDD|238640	cd01315, L-HYD_ALN, L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in biotechnology). But L-HYDs differ by having an L-enantio specificity and by lacking activity on possible natural substrates such as dihydropyrimidines. Allantoinase catalyzes the hydrolytic cleavage of the five-member ring of allantoin (5-ureidohydantoin) to form allantoic acid.	0
NZ_CP006871.1|WP_037636072.1|7382869_7383301_+|ribonuclease	gnl|CDD|238340	cd00607, RNase_Sa, RNase_Sa. Ribonucleases first isolated from Streptomyces aureofaciens. In general, ribonucleases cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. RNAse Sa is a guanylate specific endoribonuclease which belongs to the superfamily of microbial ribonucleases. Typical of this sub-family, the enzyme hydrolyses the phosphodiester bonds of RNA at the 3' oxygen end of guanosine residues to yield oligonucleotides with the guanosine-2',3'-cyclophosphate at the 3' end and the hydroxyl group at the 5' end. The terminal guanosine-2,3'-cyclophosphate is hydrolysed by guanyl RNAses to give guanosine-3'-phosphate.	1.20272e-45
NZ_CP006871.1|WP_106966072.1|7367413_7368463_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.1505e-06
NZ_CP006871.1|WP_020930886.1|7368642_7370283_-|malate-synthase-A	gnl|CDD|236432	PRK09255, PRK09255, malate synthase; Validated.	0
NZ_CP006871.1|WP_016576298.1|7385330_7386224_-|LysR-family-transcriptional-regulator	gnl|CDD|182137	PRK09906, PRK09906, DNA-binding transcriptional regulator HcaR; Provisional.	3.81757e-39
NZ_CP006871.1|WP_016577434.1|7382260_7382644_-|VOC-family-virulence-protein	gnl|CDD|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	6.68417e-25
NZ_CP006871.1|WP_078487227.1|7386210_7387641_+|MFS-transporter	gnl|CDD|369468	pfam07690, MFS_1, Major Facilitator Superfamily.	5.07231e-17
NZ_CP006871.1|WP_016578998.1|7370652_7371231_-|nucleotidyltransferase-family-protein	gnl|CDD|133025	cd04182, GT_2_like_f, GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.86383e-53
NZ_CP006871.1|WP_016578995.1|7372426_7373230_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	5.68831e-73
NZ_CP006871.1|WP_020930890.1|7377407_7378538_+|allantoicase	gnl|CDD|237319	PRK13257, PRK13257, allantoicase; Provisional.	3.84061e-176
NZ_CP006871.1|WP_016578994.1|7373490_7374297_+|hydantoin-racemase	gnl|CDD|226611	COG4126, COG4126, Hydantoin racemase [Amino acid transport and metabolism].	6.26447e-60
NZ_CP006871.1|WP_016576299.1|7384445_7385282_+|transporter-substrate-binding-domain-containing-protein	gnl|CDD|270231	cd01069, PBP2_PheC, Cyclohexadienyl dehydratase, a member of the type 2 periplasmic binding fold protein superfamily. This subfamily includes cyclohexadienyl dehydratase PheC. These proteins catalyze the decarboxylation of prephenate to phenylpyruvate in the alternative phenylalanine biosynthesis pathway in some proteobacteria and archaea. The PheC proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. Since they the PheC proteins are so similar to periplasmic binding proteins, (PBP), it is evolutionarily plausible that several pre-existing PBP proteins might have been recruited to perform the enzymatic function.	1.32929e-120
NZ_CP006871.1|WP_020930888.1|7374339_7375893_+|NCS1-family-nucleobase:cation-symporter-1	gnl|CDD|271404	cd11555, SLC-NCS1sbd_u1, uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	0
NZ_CP006871.1|WP_016577435.1|7381545_7382178_-|XRE-family-transcriptional-regulator	gnl|CDD|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.50172e-23
NZ_CP006871.1|WP_016576300.1|7383642_7384311_+|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl|CDD|180618	PRK06552, PRK06552, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional.	1.63992e-60

Protein sequences

>NZ_CP006871.1|WP_020930890.1|7377407_7378538_+|allantoicase
MTTGEPPRYTGDASPYGGGDPYADYRTPGPAGFPFSHLPDLADRRLGAGVLAANDEFFAERENLLKPEAAHFDPEAFGHKGKVMDGWETRRRRGTDGAHPFPTEEDHDWALIRLGAPGVIRGIVVDTAHFRGNYPQSVSVEGTCVEGSPSPAELLGADVTWTPLVQRTAIGGHAANGFAVHIEQRFTHLRLNQHPDGGVARLRVHGEVVPAPRWLAALGTFDLAALENGGQVEDASDRFYSSPTNTIQPGRSRKMDDGWETRRRRGTGNDWVRYRLTEQSAIRAVEIDTGYLKGNAAGWAALSGRDGEQGDWVELLPRTRLQPDTVHRFLLDDAPAVTHVQLDIFPDGGIARLRLHGSLTDDGAARLTARHRELGG
>NZ_CP006871.1|WP_016573510.1|7376070_7377411_+|allantoinase-AllB
MSEIELVLRSTRVVTPEGTRAASVTVQDGKIVAVLPHDAEAPAGARVEDFGDDVLLPGLVDTHVHVNDPGRTEWEGFWTATRAAAAGGITTLVDMPLNSLPPTTTVDNLDTKRAVARSKAHIDVGFWGGAIPGNVKDLRPLHEAGVFGFKCFLSPSGVDEFPQVDQEQLAAALGEIAAFDGLLIVHAEDPGHLDAAPEPHGPKYADFLASRPRVSENDAIAGLIELARKLDARVHVLHLSSSDALPTIAAARADGVKITVETCPHFLTLTAEEIPDGATEFKCCPPIREAGNQDALWQGLADGTIDCIVSDHSPSTTDLKTPDFGTAWGGISSLQLGLPAIWTAARERGHSLEDVVRWMSAAPAELVGLGSKGGIAPGRDADFAVLAPDATFTVDPAELQHRNKITAYAGKTLYGVVRSTWLRGRKINDGATLAEPTGELLERPRA
>NZ_CP006871.1|WP_020930888.1|7374339_7375893_+|NCS1-family-nucleobase:cation-symporter-1
MSTSPQHRPGPPDPRLFNEDLAPAAKRTWGTYSVFALWMSDTHAISNYAFAASLFVLGLPAWEVFLALLVGITIVYWLMNRMGHAGHRTGVPYPVLARASWGVYGANIPALLRAVMAVAWYGIQTWLASTAVVLLTLQIAPGLDAYNHNSVLGLSTLGWIAFMVMWGLQAALLTRGMEFIRKVQDFATGPVVWLVVLALAVYLVIAAHGDISLTRSLTGLSGTAQVRQSLIAVSLTVATFLTLVLNYADFARFTPDHRSYRRGNLVGLPVNFTAFAVVAVLVTAGTIAVFGEAIYDPVKVIQKIDNPVVTVIGALAFIVATIGINVVANFVSPAYDFANLLPKYLDFKRGGMITAVLAVLVMPWKLYSSALVIQYFLGALGAFLGPLVAILLVDYYLVRRGRIDVDALFSADAAGAYFYRRGYNPKAVIAFLPAAAVSASVALIPALDAVAPFSWIFGMGISGLLYAFVSRRERAAAGAGPIPQDIIASQVRGEMVTSVEEPERSGAIAGPAAASGS
>NZ_CP006871.1|WP_016578994.1|7373490_7374297_+|hydantoin-racemase
MRILVMNPNTTASMTASIRATATAVAAPGTEILATEPLWGPESIEGHFEGYLSAAAVLDRLATLDTPFDALVMAGFGEPGREGAQELLDVPVLDITECAAQMALMLGHSYGIVTTLDRAVPQIRDRLLTAGLLQRCAGVRGTGLGVLELEEDPERTVEVILQTARAVVRDGAEVICLGCGGMAGLQERVAAELGVPVVDGVAAAVKFAEAVVGLGLTTSAQRSFAPPRPKAIGSWPLSRHLARTAAGERYRMHDSARHTDFSSETSGI
>NZ_CP006871.1|WP_016578995.1|7372426_7373230_-|IclR-family-transcriptional-regulator
MPPSSASTSAAHAKPAGASGGVQSLERAFDLLERMADAGGEVGLSELSASSGLPLPTIHRLMRTLVACGYVRQQPNRRYALGPRLIRLGESASRLLGTWARPFLARLVEETGETANMALLDGDEIVYVAQVPSRHAVRMFTEVGRRVLPHSTGVGKALLANHPPEEVRALLGRTGMPAATEKTITDPEHFLDALADVRRLGYAVDDNEQEIGVRCLAVPVPNSPTSAAISISGPTGRVTEAATDKIIPVLQEVAAELSVALANQTPA
>NZ_CP006871.1|WP_016578996.1|7372107_7372395_+|hypothetical-protein
MTGDRNDPRVRALRVAVGRLRRQLAVLPGELPDRAAADDELAALDAMVSHGAPEVIRLRRSLLLIAGAVGSVSALSPALSEVRERIDGFGGLPGG
>NZ_CP006871.1|WP_016578997.1|7371364_7371595_-|hypothetical-protein
MEPNPGPNPGPHPDSRHLSVVQLICRAYGLADASEITEEHIHRYVSERRDADERTARLRDRLRPWIPRQRTSGDAA
>NZ_CP006871.1|WP_016578998.1|7370652_7371231_-|nucleotidyltransferase-family-protein
MAGLLLAAGGGRRLGGRPKALLDHRGRPLVEHAARVLRDAGCGPVHIVLGAAAETVRARAELAGYGVSVNPDWAEGMGSSLRVGLAALAGSGADAVVVSLVDQPGIGAAAVSRVVAACTGRDALAAAAYGGERGHPVLFGAARWAAIAASATGDRGARDYLRQHAGALTLVECGDVAEAYDIDTPEDLRRLQ
>NZ_CP006871.1|WP_020930886.1|7368642_7370283_-|malate-synthase-A
MSAPAPSPLAIVEVDPAHTPERQGEVLTDAALAFVAELHRRFTPRRDELLARRAERRAEIARTSTLDFRPETAQIRADDSWKVAAAPAALNDRRVEITGPTDRKMTINALNSGAKVWLADFEDASAPTWENVVNGQLNLIDAYERRIDFTDARSGKSYALKPAEELATVVMRPRGWHLEERHLQFEGRPVPGALVDFGLYFFHNAQRLLDLGKGPYFYLPKTESHLEARLWNEIFVFAQDYVGIPQGTVRATVLIETITAAYEMEEILYELRDHASGLNAGRWDYLFSIVKNFRDGGAKFVLPDRNAVTMTAPFMRAYTELLVRTCHKRGAHAIGGMAAFIPNRRDPEANERALAKVKNDKDREAGDGFDGSWVAHPDLVPIARASFDAVLGEKPNQKDRLREDVSVAAADLIAIDSLDAKPTYQGLVDAVQVGTRYIEAWLRGLGAVAIFGLMEDAATAEISRSQIWQWVDAGVVFAEEGHAGTKVTADLVRTIAAEELAAIRAEVGDEAFTGGKWQQAHDLLLKVSLDADYADFLTLPAYELLV
>NZ_CP006871.1|WP_106966072.1|7367413_7368463_+|GNAT-family-N-acetyltransferase
MRQPVAAQPKGRLDSAGRPRSRGPTPSTRRCGAHAHECPSARPAHRPSPPPHDGDTLSLRLTALTDPAHGPHGRRLAWLASDADSHPVGTAFLRLFTDPGREHLAELALHVHPVERRRRVGSRLLDAAVATAREHGRRRVISQAEAGSPGDRFLAARGFRTVLTLRYTRLPLADVDTGALDRIVERPHPGYRLASWRGTVPDHLVQTFVASRHAMDDMPMGDPDRATVSWDEDRVRAAAQAVEGRGDHLHTVAAVDTRDGSIAGFTELVVPGSGTGDGQHYGTGVLPEHRGHGLGRWMKAASIRQALADHPDLAGLLTDTAVGNAPMRRINDALGYAPTHLTHQHQREL
>NZ_CP006871.1|WP_037683385.1|7379215_7381141_-|beta-N-acetylhexosaminidase
MHRTRTAAVTGLAVTLAVIPLAGMAGPSGAAPARGTDGSRARPATATLSPAPQSVHDRSDHLTVTGTVTLVAGPKADAPALALVTTSLKAAGAQRVVRTDRVAPQAGRLTVYVDGPGAARALTALGARGTAGLPAEGYALAVGRGRITLAGKDATGTYYAAQTLAHLLPHRDRPGAQVPGAVVRDWPATPLRGVIEGFYGTPWSHAARLDQLDFAARHKMNIYVYSPKDDAYLREKWRDRYPADQLDRIKELVDRARARHVEFTYALSPGLSVCYSSAADVKALTAKFATLWDIGVRTFAVPLDDISYTKWNCAADKEKFGTGGAAAGTAQAQLLNQVNREFIARHPGARPLQMVPTEYYDLKATPYKAALATKLDANVLVEWTGVGVIAPTMTAAQAQQARELFGHPILLWDNYPVNDYVSKRLMLGPYNGRAPGVPGRLAGITANPMIQPSASKLALATVADYAWNDRAYDARDSWSTAIEELAGGDARAARALRAFADVNYTSAINPKQAPELSAALDRFRKGGEARRLDAVLHDLQDAPGVLRDRLPDRGVAREATPWLDATHAWAVAARDALRLIEADRSGDTAKAKQLRAQIPELVTKAKSYVYVDLKGKRIPVVVGDGVLDTFVADALAGRGGH
>NZ_CP006871.1|WP_016577436.1|7381293_7381488_-|hypothetical-protein
MPDHTTPDPATPPTAGGAPDAAAPRRYVENKPPRGLYVRVFIYVVATHVLLAFMSVLVLVAKSR
>NZ_CP006871.1|WP_016577435.1|7381545_7382178_-|XRE-family-transcriptional-regulator
MIELPDPPSDPAPEELSTAVAPRLRELRRHSALTLETAARRVGLSPAHLSRLETGQRQPSLPMLLSLARTYGTTVSDLLGETAPEHDPIVRAARAEPSEAGGWTYRTVGGAGRAMQALRVHVPERAQGDLVRVHPGEEWLYVLTGRLRLTLGEAVHVLEPGDAAHFDSLTPHRLAAAARGGTELLFVHTLLQSGAAELCLGDRTPHRRGG
>NZ_CP006871.1|WP_016577434.1|7382260_7382644_-|VOC-family-virulence-protein
MHVKDFDHLVLTVQDVERSLEFYCGPLGLEPVRVDAWRAGEAPFPSVRVSPTTIIDLVTGDRAGTNVDHICLVVDPLDWQEVIDSGAFTVLEGPVGRYGARGDAQSIYVADPDGNTVELRWYPQDVR
>NZ_CP006871.1|WP_106966070.1|7382642_7382873_+|hypothetical-protein
MGVPPVGVGVGLGVGVAGGVVGVWVMRGAGVVGVGVAAAEHSGRLGVTLRGPCELPGNIGSLGLTGPCLRASCWFA
>NZ_CP006871.1|WP_037636072.1|7382869_7383301_+|ribonuclease
MRIPPRMTRIGAAGALASALLLGGTAVAATPAAPTHHAAVHTATVHVKSVGSVCYSKLPSQAHDTLDLIDKGGPFPYPKDGTVFDNREGILPSQSSGYYHEYTVVTPGSPDRGARRIVAGQKQQEDYYTADHYATFNLVNFGC
>NZ_CP006871.1|WP_016576300.1|7383642_7384311_+|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MYRWEITRAALAQRVFAIVRSKTYDEASATADTLLSAGITSLEISLTTPFALEAVTTLSRELGDDAVIGAGTVLDAASARMAVDAGARFLVSPSLDASVISAGHRYGVPVFAGVSTPTEIVRGLELGADALKLFPAAGHHPSWVSDVRAALPQAPLVPTGGVTTETAPEWIAAGAVAVGMGSALSEGDRDTVAKRAADLLARLADAVPEQPGQAGALDPYGA
>NZ_CP006871.1|WP_016576299.1|7384445_7385282_+|transporter-substrate-binding-domain-containing-protein
MKRAATLPALACLLVATAAAPAASSAPAAGSAAAAAAQRDRRPATLLDEVPRRGVLRVCTTGDYRPFSYRDPATGDYRGVDIDMARDLAKSLDATPRYVPTTWSGLVGDLTAGRCDIGMGGVSITLARARSVAFSEPTRTDGKTPVVRCADQDAYRTLDQIDRPGVRVVVNPGGTNEQFARAHVKRATLTVHPDNTTIFDEIIAGRQDVMMTDASETRYQAKIHPELCAVHPDQPFTFSEKAYALPRGDAEFTAYVNQWVHLATHDGTYRRYEDAWMK
>NZ_CP006871.1|WP_016576298.1|7385330_7386224_-|LysR-family-transcriptional-regulator
MDAHIRDLRYFLATAEELHFTRAAERLFVSQPALSKQIRQLEEGLRVRLFHRDRRTVTLTAAGTALLPRARELVGLWDEAQRAVSDAAAAEAAELTLGVSTSVGRGLLPAIRARFAERRPNWRIRVRQITWDDGTAGLADGTADLALLWLPCPGQEALAVEVVATEPRWVALPAGHRLADAAEIPFAELLDEPFLALPESAGALRDHWLAASERDGRPVRVGAVVAGADETFEAVAEGLGVVLLAAGNAAIYRRPGVVTRPVSGLSPSRLALAWRADDHRTVLRDVLEAVRQARPAA
>NZ_CP006871.1|WP_078487227.1|7386210_7387641_+|MFS-transporter
MWASITPGYQKGSWTGNGRRRHDRPMDSSSPHQLPARKPPLGRRPVSAPPSAGSGAAGGGSRWGRLVATVVVTVGAVTPGLMVPALAAPVPGAPPLSATAYGAAVTCFFACTAAGAPLARRIVPRMPVRAVLGAVGLLTVGVFAGLAVAGRAWQLCLLLALAGLGNAFTQPVAARVIAADIAPGRHSFAGGLFGASLGAGPFLPGLLVTLVGAPYGWRPALWTAAGLALLTLVAAALARPAADGRAVPEQGRAVTAVGAPAAVAAPTPRTVGRVVVAWSAAAALATIGNNVGAAYFIQIGSASGFSAATAGTLQMVASVLGIAVRLASGGLADRAPHRIPRTVAVMMLTGTVGLAVIVVGTPVAFVAGALLAVAGGWGWTGLLLAATMRLLPGESARAGAAMQGGLFAGAAVGPLSFGVLSGQLGIPTTVGIAAVGPLLGALLLGVGIRALARDGAGRAAPAAPPASAAVRADEAR

Crispr_ID: NZ_CP006871_11

• CRISPR_ID: NZ_CP006871_11
• CRISPR_location: 9042557-9043273
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 16 spacers

Consensus repeat of NZ_CP006871_11

Consensus_repeat	Method
CCGTCGTGCTGTTGCGGNGTGGGG	CRT

spacers of NZ_CP006871_11

>11.1|9042581|39|NZ_CP006871|CRT
TCGTGTTGTTGGGGGGTGGGGTTGTTTCCCTGTGCTGGT
>11.2|9042644|18|NZ_CP006871|CRT
TTGTGGTTTTGTGTCGGG
>11.3|9042686|18|NZ_CP006871|CRT
CTGTGGTCCTGTGTCGGG
>11.4|9042728|18|NZ_CP006871|CRT
TTGTTTCCCTGTGCCGGG
>11.5|9042770|18|NZ_CP006871|CRT
CTGTGGTCCTGTGTCGGG
>11.6|9042812|18|NZ_CP006871|CRT
TTGTTTCCCTGTGTCGGG
>11.7|9042854|18|NZ_CP006871|CRT
TTGTTTCCCTGTGCTGGC
>11.8|9042896|18|NZ_CP006871|CRT
TTGTTTCCCTGTGCTGGC
>11.9|9042938|18|NZ_CP006871|CRT
CTGTGGTCCTGTGCCGGC
>11.10|9042980|18|NZ_CP006871|CRT
TTGTTCCCCTGCGCTGGC
>11.11|9043022|18|NZ_CP006871|CRT
TTGTTTCCCTGTGCCGGC
>11.12|9043064|18|NZ_CP006871|CRT
TTGGTTCCCTGCGTTGGC
>11.13|9043106|18|NZ_CP006871|CRT
CTGTGGTCCTGTGCCGGC
>11.14|9043148|18|NZ_CP006871|CRT
TTGTTCCCCTGCGCTAGC
>11.15|9043190|18|NZ_CP006871|CRT
CTGTGGTCCTGTGCCGGC
>11.16|9043232|18|NZ_CP006871|CRT
TTGTTCCCCTGCGCTGGC

CRISPR arrays and Neighbor proteins around NZ_CP006871_11

CRISPR arrays

The CRISPR arrays of NZ_CP006871_11

>merge|NZ_CP006871|11|9042557-9043273|CRT
CCACCGTGCTGCTGCGGTGTCGTGTCGTGTTGTTGGGGGGTGGGGTTGTTTCCCTGTGCTGGTCCGTCGTGCTGTTGCGGTGTGGGGTTGTGGTTTTGTGTCGGGCCGTCGTGTTGCTGCGGTGTGGGGCTGTGGTCCTGTGTCGGGCCGTCGTGCTGTTGGGGGGTGGGGTTGTTTCCCTGTGCCGGGCCGTCGTGCTGTTGCGGTGTGGGGCTGTGGTCCTGTGTCGGGCCGTCGTGCTGCTGTGGAGTGGGGTTGTTTCCCTGTGTCGGGCCGTCGTGCTGTTGTGGGGTGGGGTTGTTTCCCTGTGCTGGCCCGTCGTGCTGTTGTGGGGTGGGGTTGTTTCCCTGTGCTGGCCCGTCGTGCTGTTGCGGAGTGGGGCTGTGGTCCTGTGCCGGCCCGTCGTGCTGTTGCGGAGTGGGGTTGTTCCCCTGCGCTGGCCCGTCGTGCTGTTGCGGAGTGGGGTTGTTTCCCTGTGCCGGCCCGTCGTGCTGTTGTGGGGTGGGGTTGGTTCCCTGCGTTGGCCCGTCGTGCTGTTGCGGCGTGGGGCTGTGGTCCTGTGCCGGCCCGTCCTGCTGTTGCGGAGTGGGGTTGTTCCCCTGCGCTAGCCCGTCGTGCTGTTGCGGAGTGGGGCTGTGGTCCTGTGCCGGCCCGTCGTGCTGTTGCGGAGTGGGGTTGTTCCCCTGCGCTGGCCCGTCGTGCTGCTGCGGAGTGGAG

>NZ_CP006871|11|3|9042557-9043273|CRT
CCACCGTGCTGCTGCGGTGTCGTG	TCGTGTTGTTGGGGGGTGGGGTTGTTTCCCTGTGCTGGT
CCGTCGTGCTGTTGCGGTGTGGGG	TTGTGGTTTTGTGTCGGG
CCGTCGTGTTGCTGCGGTGTGGGG	CTGTGGTCCTGTGTCGGG
CCGTCGTGCTGTTGGGGGGTGGGG	TTGTTTCCCTGTGCCGGG
CCGTCGTGCTGTTGCGGTGTGGGG	CTGTGGTCCTGTGTCGGG
CCGTCGTGCTGCTGTGGAGTGGGG	TTGTTTCCCTGTGTCGGG
CCGTCGTGCTGTTGTGGGGTGGGG	TTGTTTCCCTGTGCTGGC
CCGTCGTGCTGTTGTGGGGTGGGG	TTGTTTCCCTGTGCTGGC
CCGTCGTGCTGTTGCGGAGTGGGG	CTGTGGTCCTGTGCCGGC
CCGTCGTGCTGTTGCGGAGTGGGG	TTGTTCCCCTGCGCTGGC
CCGTCGTGCTGTTGCGGAGTGGGG	TTGTTTCCCTGTGCCGGC
CCGTCGTGCTGTTGTGGGGTGGGG	TTGGTTCCCTGCGTTGGC
CCGTCGTGCTGTTGCGGCGTGGGG	CTGTGGTCCTGTGCCGGC
CCGTCCTGCTGTTGCGGAGTGGGG	TTGTTCCCCTGCGCTAGC
CCGTCGTGCTGTTGCGGAGTGGGG	CTGTGGTCCTGTGCCGGC
CCGTCGTGCTGTTGCGGAGTGGGG	TTGTTCCCCTGCGCTGGC
CCGTCGTGCTGCTGCGGAGTGGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006871.1|WP_016577068.1|9045034_9045415_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016576890.1|9048170_9050942_+|sensor-histidine-kinase-KdpD	unknown	unknown	gnl|CDD|225115
NZ_CP006871.1|WP_016577361.1|9036267_9036726_-|SRPBCC-domain-containing-protein	unknown	unknown	gnl|CDD|176856
NZ_CP006871.1|WP_016576889.1|9051002_9051272_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016574632.1|9037365_9038361_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016574633.1|9036839_9037172_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_016576896.1|9028745_9029537_-|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl|CDD|224268
NZ_CP006871.1|WP_045788641.1|9056975_9058079_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_020930390.1|9030125_9031175_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP006871.1|WP_020930393.1|9035100_9036000_-|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|274373
NZ_CP006871.1|WP_016577342.1|9032143_9033694_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187556
NZ_CP006871.1|WP_020930392.1|9031571_9032003_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP006871.1|WP_020930174.1|9052266_9053313_-|hypothetical-protein	unknown	unknown	gnl|CDD|366359
NZ_CP006871.1|WP_051273446.1|9045746_9047960_+|mannosyltransferase	unknown	unknown	gnl|CDD|224720
NZ_CP006871.1|WP_020930391.1|9031247_9031583_-|hypothetical-protein	unknown	unknown	gnl|CDD|274699
NZ_CP006871.1|WP_020930173.1|9054434_9056087_-|multicopper-oxidase-family-protein	unknown	unknown	gnl|CDD|225043
NZ_CP006871.1|WP_016577341.1|9033690_9035064_+|deoxyribodipyrimidine-photo-lyase	unknown	unknown	gnl|CDD|223492
NZ_CP006871.1|WP_016577289.1|9053655_9054321_-|dimethylmenaquinone-methyltransferase	unknown	unknown	gnl|CDD|180465
NZ_CP006871.1|WP_020930175.1|9051281_9052226_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187540
NZ_CP006871.1|WP_016576859.1|9056194_9056644_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP006871.1|WP_016576890.1|9048170_9050942_+|sensor-histidine-kinase-KdpD	gnl|CDD|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NZ_CP006871.1|WP_016577361.1|9036267_9036726_-|SRPBCC-domain-containing-protein	gnl|CDD|176856	cd07814, SRPBCC_CalC_Aha1-like, Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Micromonospora echinospora CalC, human Aha1, and related proteins. Proteins in this group belong to the SRPBCC domain superfamily of proteins, which bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. MeCalC confers resistance to the enediyne, calicheamicin gamma 1 (CLM), by a self sacrificing mechanism which results in inactivation of both CalC and the highly reactive diradical enediyne species. MeCalC can also inactivate two other enediynes, shishijimicin and namenamicin. A crucial Gly of the MeCalC CLM resistance mechanism is not conserved in this subgroup. This family also includes the C-terminal, Bet v1-like domain of Aha1, one of several co-chaperones, which regulate the dimeric chaperone Hsp90. Aha1 promotes dimerization of the N-terminal domains of Hsp90, and stimulates its low intrinsic ATPase activity, and may regulate the dwell time of Hsp90 with client proteins. Aha1 can act as either a positive or negative regulator of chaperone-dependent activation, depending on the client protein, but the mechanisms by which these opposing functions are achieved are unclear. Aha1 is upregulated in a number of tumor lines co-incident with the activation of several signaling kinases.	8.14671e-27
NZ_CP006871.1|WP_020930390.1|9030125_9031175_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	5.3353e-12
NZ_CP006871.1|WP_016576896.1|9028745_9029537_-|DeoR/GlpR-transcriptional-regulator	gnl|CDD|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.86472e-63
NZ_CP006871.1|WP_051273446.1|9045746_9047960_+|mannosyltransferase	gnl|CDD|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	2.93293e-25
NZ_CP006871.1|WP_020930393.1|9035100_9036000_-|RNA-polymerase-sigma-factor-SigF	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	1.79613e-107
NZ_CP006871.1|WP_016577342.1|9032143_9033694_+|SDR-family-oxidoreductase	gnl|CDD|187556	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2. This subgroup contains atypical SDRs, one member is identified as Escherichia coli protein ybjT, function unknown. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif consensus that generally matches the extended SDRs, TGXXGXXG, but lacks the characteristic active site residues of the SDRs. This subgroup has basic residues (HXXXR) in place of the active site motif YXXXK, these may have a catalytic role. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.91008e-148
NZ_CP006871.1|WP_020930174.1|9052266_9053313_-|hypothetical-protein	gnl|CDD|366359	pfam00891, Methyltransf_2, O-methyltransferase. This family includes a range of O-methyltransferases. These enzymes utilize S-adenosyl methionine.	6.82818e-31
NZ_CP006871.1|WP_020930173.1|9054434_9056087_-|multicopper-oxidase-family-protein	gnl|CDD|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	3.13723e-78
NZ_CP006871.1|WP_020930391.1|9031247_9031583_-|hypothetical-protein	gnl|CDD|274699	TIGR03649, ergot_alkaloid_biosynthetic_protein_A, ergot alkaloid biosynthesis protein, AFUA_2G17970 family. This family consists of fungal proteins of unknown function associated with secondary metabolite biosynthesis, such as of the ergot alkaloids such as ergovaline. Nomenclature differs because gene order differs - this is EasG in Neotyphodium lolii but is designated ergot alkaloid biosynthetic protein A in several other fungi.	2.08497e-30
NZ_CP006871.1|WP_020930175.1|9051281_9052226_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187540	cd05229, SDR_a3, atypical (a) SDRs, subgroup 3. These atypical SDR family members of unknown function have a glycine-rich NAD(P)-binding motif consensus that is very similar to the extended SDRs, GXXGXXG. Generally, this group has poor conservation of the active site tetrad, However, individual sequences do contain matches to the YXXXK active site motif, and generally Tyr or Asn in place of the upstream Ser found in most SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.28742e-92
NZ_CP006871.1|WP_016577289.1|9053655_9054321_-|dimethylmenaquinone-methyltransferase	gnl|CDD|180465	PRK06201, PRK06201, hypothetical protein; Validated.	5.21315e-50
NZ_CP006871.1|WP_016577341.1|9033690_9035064_+|deoxyribodipyrimidine-photo-lyase	gnl|CDD|223492	COG0415, PhrB, Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair].	2.53575e-119

Protein sequences

>NZ_CP006871.1|WP_016574632.1|9037365_9038361_+|hypothetical-protein
MSEEIAALVRRLAAESRDDRAAAQDALTALGAPVVPYLLPLLKNDGTPGGTAAELCLEDIGSAALAPLREVRAHGPGALRATALRMLAELGGGDALSDADRAAVERLVRIKLPDEQPGDLPADRWVAVPKAEVADIVDALDLHDARPVTTAMGLSAAVHHENSLSRPADDGSDATSYRVFITPEFEGWRLVYGADYLNENWAEVVTRLSAHCGEAHFYAVDEYDGAWVWWVSENGQDRRGYRTYGDPQWIGEPMEFERDLMPDEDADPDSEDYDAEAAEEYAEGVRDPEEVASSISVQPTVVEVLDRVGHGWLAVTDPEVGHGRFRGALDI
>NZ_CP006871.1|WP_016574633.1|9036839_9037172_-|hypothetical-protein
MTPDHDSPTGPQSVPTNSDEALEIVRTAFGEPRSFDGSPAPLQVREFDLGYLVYATYAKPVDASGRPLPTPPGGSSFVVAKGTGTISTLPNYPPDQAIALYRKQRNEKDK
>NZ_CP006871.1|WP_016577361.1|9036267_9036726_-|SRPBCC-domain-containing-protein
MSNNEAIRVPDLSSRPHELSVERLMGAPPAALYRAWTEQVDRWFAAPGSVLMQGRPNTAFFFETEHEGARHPHYGRFLRLEPDRLIQLTWVTGAGGTEGAETVVTVECAAEGTGTRLRLTHAGFADEAARDRHREAWPHVLEQLDRRIDASG
>NZ_CP006871.1|WP_020930393.1|9035100_9036000_-|RNA-polymerase-sigma-factor-SigF
MTTAVSTHTGIRHGHVQGPEHRTVSSGTGGLPYVADASKVAPKSAKALSRPFFERLAELEEGTHAYQYVRNTLVEMNLSLVRYVAARFRNRGGDPSEMEDIVQVGTIGLIKAIDRFDLSREVEFTTFAVPYIMGEIKRFFRDATWAVHVPRRLQELRIELAQAKERLFARLDRDPTVAELAQHLGIGEDQVIDGLIAGNGYTAGSLDQPTDPADDDSARTLADALGDEDPRLQLAEDLHALTPLVQKLDRRDRRILTLRFVHEKTQSEIGEELGVSQMHVSRLLARILGRLRTGLVGQS
>NZ_CP006871.1|WP_016577341.1|9033690_9035064_+|deoxyribodipyrimidine-photo-lyase
MTVAVVLYTSDLRLHDHPPLRAALRSADAVVPLFVHDDALAATGFATPNRRAFLADCLTQLDAGLRERGGRLVIRTGDVVEEVCRVATEADATEVHLAAGVSGYATRREEKLRNALEAARRRLCVHDAVITAVPPGAVAPAAKDHFAVFTPYFRHWSQQHLRDPLAAPRKVPVPDHLDSADLPSTEDRSGVSEGLAEGGETVGRKRLTAWLRSGAAEYADRHDDLAGDATSRLSPHLHFGTLSPVELVQRARSQGGAGADAFVRQLAWRDFHHQVLAARPAASTADYRTRHDHWRSEEAAAEEIAAWKAGRTGYPMIDAAMRQLSHEGWMHNRGRLLTACFLTKTLYVDWRVGARHFLDLLVDGDVANNQLNWQWVAGTGTDTRPNRVLNPLLQAKRYDPDGAYVRRWVPELAGLAAPAVHQPWRLRAEERAGYDYPEPVVQLDDALARFKRARGRD
>NZ_CP006871.1|WP_016577342.1|9032143_9033694_+|SDR-family-oxidoreductase
MNDRETAPEEHRGRACLVTGATGYIGGRLVPELLAAGHTVRCLARSPDRLRDHPWAGDVEAVRGDVTDAASVGAAMHGIDVAYYLVHALGTGKGFEETDRRAARIFGEQARAAGVRRIVYLGGLTPSGVPEDELSPHLRSRAEVGRVLMDSGVPTAVLRAAVIIGSGSASFEMLRYLTERLPVMVTPSWVHTRTQPIAVRDVLRILVGCAGLPTDVNRTFDIGGPEVLSYREMMRRYALIAELPRRLILPVPVLTPRLSSHWVGLVTPVPSKIARPLTESLRNEVVCREHDITRSVPDPPGHPFGFDTAVSLALQRIREAQVTTRWSSASVPGAPSDPLPTDPDWAGGSLYSDCRELDVDAPCDALWRVIEGVGGVHGWYSFPLAWVIRGWLDRLVGGVGLRRGRRDASRLRVGDSLDFWRVEEIEPGRLLRLRAEMRLPGLAWLEMSCRATDDGRSHYRQRAVFHPHGLLGHAYWWSVSPFHAVVFGGMARNIARAAADTAPTDQSDQSDKGVTP
>NZ_CP006871.1|WP_020930392.1|9031571_9032003_+|hypothetical-protein
MRGHRGDVLGVDERRTAPLRRAVAEGPAPLGPDTPPHQRVPAVFDALARFKLDNQSLYLVLEEAGASSPYESPSYAWWHTTPRDSLAQCTDAERAGFLAHVLLAAVRADLIAHLVTVERLSVEEIRTRLAAHVHSVLPADARR
>NZ_CP006871.1|WP_020930391.1|9031247_9031583_-|hypothetical-protein
MAAHALTDPTPPNTDWILTGPQALSYDAVAAVLTEVTGRPVRHRSVSVEEMRARHARVMPPEFATVLADVDRRIADGAEDRTTDAVARLTGRPPRSFTTYAEDNSDALTTS
>NZ_CP006871.1|WP_020930390.1|9030125_9031175_+|cytochrome-P450
MPQRSTASRGGRQVRFAPRIDALLRQHTGQDLFRLEPTTVGVGGADLMDALLRSRPANAEERPTFKPVLGRHVSRADAATYMQAVAADVRKALQRPLEAPVDLTGPWPQVPHAYLRDLVFGRELLRFRVLVDRRLELTPKLTWSAVTSGAALLRRPDSTEPLSKLAALVLGATGFPDRRYAMYLYRRVAAPICFTVAALVTNAVWLGAPFDDSVPNRHLLAEALRLLPPSWNILRMASPEFTVLDTRIGPADDVLLLPLLSHRDPALWEEPDAFRPERWADLDPDDHPGYLPFGHANERCWGRHMVLPLAERLLDLVRRDGLTVRPAQTVGRVELDGLMEVAEVRVMRG
>NZ_CP006871.1|WP_016576896.1|9028745_9029537_-|DeoR/GlpR-transcriptional-regulator
MRPSRGSEAEVEERRQAVLRLVAQDGEIRIAALAERMRVSLMTMHRDLDNLHQRQLLRKGRGVATAFPDVTMESALRFREHAHADVKTAFAEALVGEVAPGDTVLIDCGSTLFPLARRLAAVDGLRVITNSLRVTALLAGSAVEVTVLGDRYYEDFESCAGPQARRQLQDLRADLAFVTATSVREGRLFHPVHAYAESKHAYLRAADRAVLVVDHSKFGRTATHPYGDVGGYDLMVTDAATPESEVRAVRDLGVEVRTVDPGT
>NZ_CP006871.1|WP_016577068.1|9045034_9045415_-|hypothetical-protein
MGDGFKADVPSLRTGGSDFDQIGKDYQSLVDKLESALTSLEGSDTPPWGDDDLGEKFGIVYEGLRDGMYESMAHLAKKLQEIGGGLTNMAKNHEADEESTDAVMQRHLSEAKTESQAVGRLKSPNL
>NZ_CP006871.1|WP_051273446.1|9045746_9047960_+|mannosyltransferase
MASTTSAGSVSAGEHASPAGDASPPGAPTVPANATSPASTPPAAPTPTGRTGRGGLLARVRASRTDAAPRPAYARPALLAILALAAVLFAWDIQHSAFHTFYAETARSMAESWHAFLFGSFDPGGSITIDKLPGFLWPQALAVRIFGFHPWALTLPQVIEGVLSVAVLYRAVRRWAGEHPALLAAAAFAVTPAIAGLFRTPVEDPAFTLCVLLAADATLRAARLGRLRPLVAAGVWVGLGFQAKMLEAWGVLPALGLLYAFSAPTALRRRLAHLSVAGAVCLAVSASWVLLVTFTPAKDRPYVDGTTNNSAVSQVVGYNFLNRFSSVNVSAAHTGSVAVSTMAGTAPAPPTGRSRPTAAQWLKMFAPSLVSQIGWLYPAAALAAVCGLVWRRGRPRTDPLRAGFVLWAVWLATYFLVFSAGAIGGHTYYMGVLAVPLAALFGAGTVQFWRAWLRGGRRRAWALPTVVVATVAWSAALARLFPTFLPWLAPVAVALGVGALVLMARARPGRTAGTGAVRRRTAVLGLVTGLVAMLLPSAAWASSVLDPEYGHSGMGSTGPVANWHRLAAERAAAARLAAHRPRRPDGATPNPNEGGAAAEPSPGRSPAKSADASPDGSGLTAVQQQLLAYTRAHQGGARYLFATTSWRTASPYILHAGAAVLPMGGFTGTAPTPTAAGFRELVATGQLRYVVLGGPATDPGRAIAPWVRAHCDRVPGQAHRLYRCAPEPATARPAPGR
>NZ_CP006871.1|WP_016576890.1|9048170_9050942_+|sensor-histidine-kinase-KdpD
MRWATEGTGTAEEPRPGRLKVFLGAAPGVGKTYRMLDEGRRRAARGTDVLVAFAECHGRPATEAMLDGLTVLPRLIRRHRDAERAELDLDRVLERRPAVALIDELAHTNVPGGRRTKRWQDVEELLAAGIDVVATLNIQHLESLTDVVEKITGVPQFETVPDEVVRRAHEIELVDLPAEGLRRRMAHGNVYPPEKVDAALSHYFRLGNLNALRELALLWVAGRVGEALCAYRHDHRIGPVWETRERVVVALTGGPEGTTLIRRAARIVNLPRSRHPDRAAETALSAGDLLAVHIARSDGPAGSSAAALAGQRQLVESLGGSYHAVVADDVPAALLDFARAQNATQLVVGASRRGRLRRFLAPRGVGETVVELSGDIDVHTVSHERAGQGRGWPVAGSGLPRSRRVAGPIAGLVLPLLLTLVLRAVSGPLSLNLTSEALLFLLTVLGVACIGGVVSALLASVTTSLLLNYYFLPPVGEFTFAGANVVVAQAAFTTVAVTVAAIVDRSLRLGRRAARATAEAETLTSLAGGILRGDRAVPALLERTRETFGMDRIELRPRVQTGEPSWPSRVADTVATGATVATGATGAADPVRGPAAADGAGADHRTEVAIGDDSVLVLTGRRLPASEHRVLTTFAAHLTAAVERARLAETAAEVEVVKAANRMRTALLAAVGHDLRTPLAGSWAAISSLRSRDVEFSAEDRDELLATAEESLAKLSRLVDNLLDMSRLQAGALAPHREPVALADVLAAALDTLPDSPPQASGRVVARGLEEAPDALADPPLLERVIANLVSNAVRHSPAGRPVTIGASALAGRVELRIIDRGPGIQLPDRERAFEPFQRLGDTDNTTGLGLGLALSRGLTEAMGGTLVPEETPGGGLTMVVSLPAAPAPIVTAAPAVPGSGALPVAGVGAGATELGIRRHRGR
>NZ_CP006871.1|WP_016576889.1|9051002_9051272_+|hypothetical-protein
MWSGTHDDDLEQTVRALAGEIARRRSVQRARAAARAREWVAQSRRTARATEDTELQRRAVLGQIPAAEYKARTVARAAGVEVGRNPFAR
>NZ_CP006871.1|WP_020930175.1|9051281_9052226_+|NAD-dependent-epimerase/dehydratase-family-protein
MSHHVVMGFGPAGAATARLLVARGHVVRVVTTSGRSPEPGIEHVACDARDRERLTEIVRGAVALHGCAAPPYHRWAEDWPPLVSSLCAVAEETGAVLVMLGNLYGYGPVDGPLTEDLPLAATGVKGRVRASGWEQVLRRHEEGRLRAVEVRAADFFGPGVTDGGHLAAQVVPRLLRGKPVSVLGDPDAPHSWSYLPDVAAALVEVAGEERAWGRAWHVPTEPALSARQMIDRLAARAGTGPVAVRTLPPVALGVAGLFSPLIRELKEIRYQFDRPFVMDARAYEAAFAVRATPVDEQVDATVDWWRARSTTGTA
>NZ_CP006871.1|WP_020930174.1|9052266_9053313_-|hypothetical-protein
MNTPNPTDHPDLTEATAHAGAAHLIDQSLGHLYSAALRMAAVHHLADHLAGGPRTAAELARLTGTDAAFLRRCMRYLASRGIFREDANGAFHLTPAAQFLRAGVPGSLRDAVLLLTDALFVRASSALDATIRTGRPGFPQVVGAPFFEYLKEDATARELFDTGMAAFSEPLDALVAGAYPFPERGTVVDVGGGRGGLLRQVLRRHPGLTGVLLDRAPALADHVLDEPGLAGRWRAEPGDVFTAVPDGGDVYVLQRVLHAWDDDAAVRVLTACRRGLAPDGRVLVVDVVPVPGNAPPPGEALDVAMMTLVTGRRRGPKELDGLFARAGLRRTRILRTPAFASLVEAVAA
>NZ_CP006871.1|WP_016577289.1|9053655_9054321_-|dimethylmenaquinone-methyltransferase
MNDHAGSPAPDGFREIPPTTLADVLGRGQVMDIGIRPLWSPTPRVAGPAFTVRCPPGDNLMVHAAIHRAAPGSVIVVESGDLDHALAGGNVCAVAQRRGIAAFVADGLIRDLAEVRAMGFPVFARGVVPFPGGKAAVRPHNVDVRCGGVDVRAGDVVVADEEGIVVVPRDRQEQVLRAAQTKLAKEAEESLDAWEAAHRARIDAILRDGGVEGGLDGALDG
>NZ_CP006871.1|WP_020930173.1|9054434_9056087_-|multicopper-oxidase-family-protein
MKTIDRRAVLLAGLGAAGSGLLAGCSADAAGPAARGGSGPTLVSPSGAAVAAAEKKRHHSGRERRVKLTATAGAVDLGAGKTVRTWSFDGRLPGRELRVTAGDTLVAELANHLPQPTSIHWHGLALRNDMDGVPPVTQRAVAAGRAFTYRFVAETPGTYWFHPHVGVQLDRGLYGPLIVEDPHEPLGYDDEWVVVLDDWLDGVTGTPEQALAALRRGMGPDHGATPHDGKDGSPGGTGGMGGMGGMGGMGGMQGMGSSADLPGMPGMAGTDDPFILMGATSTLLGGDAGDVKYPYYLVNGRVPAAPATYRGKPGRRLRLRIVNAGGDTAFRVALGGHRLTVTHTDGYPVAHEPADALLIGPGERYDALVTLGDGVFPLVALAEGKGAAGLALVRTGSGRAPSAAVRPAELNGRIPVAGALRAVEGVRLASRRPDVTHRIALTGGMAKYDWALNGRRFAMNAADAHPFTVGSGQRVRLRFVNTTDMWHPMHLHGHTYQLGAAGPRKDTVIVLPGSTVTCDFDADNPGRWLIHCHNAYHGESGMMGLLAYDA
>NZ_CP006871.1|WP_016576859.1|9056194_9056644_-|hypothetical-protein
MRTHHRKPTARTGHRRPAALLALLWLVLSVIAHHDLPETAPATAFAPAAVAAHPHAPSGLVPAVHAPSGHRMTGPAHAGGAGHLHDDGAPCSSGAHCSSYDVRSEHVVGPPPLLGTARTARTAAPPAPGPRPVGGPSPPDPATLSVLRI
>NZ_CP006871.1|WP_045788641.1|9056975_9058079_+|hypothetical-protein
MTHPVRERQAAALAARLGLGGLALDPDPTGPPSALRTALVAWAARADDAGHHLVVQDDVAAPPELVELVAGSVTRFPDEALIFYTNWHARNGAAARLAALAGAGWVRAVPEEFAPTLAICLPVRTADAFRAFAAGTAERHDDEVMATFLRTEARPGLLAVPTVVEHIGTSSINGHAAQGIRLAVCPVGAAEARPLLDRGWVLEEWGWLPYMRYGEGYVRPVGHEHDADPRRHLRWTEALPTTGLTEGQVRDVVRRHRAEDAAASVGRLFGRGFADELWIHCLLLGRQAEDVARRHAARRAAAGPVGEAAARVRAAALSTVGPAGLPPERRPELTPEHTALMAAYAEGAVRCGGRLLGPVEGQPTEVR

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP006871_10	10.1|7378593|49|NZ_CP006871|CRISPRCasFinder	7378593-7378641	49	NZ_CP006871.1	8691862-8691910	1	0.98
NZ_CP006871_5	5.9|4828362|19|NZ_CP006871|CRT	4828362-4828380	19	NZ_CP006871.1	3364799-3364817	2	0.895
NZ_CP006871_5	5.9|4828362|19|NZ_CP006871|CRT	4828362-4828380	19	NZ_CP006871.1	3923227-3923245	2	0.895
NZ_CP006871_5	5.9|4828362|19|NZ_CP006871|CRT	4828362-4828380	19	NZ_CP006871.1	6651937-6651955	2	0.895
NZ_CP006871_5	5.9|4828362|19|NZ_CP006871|CRT	4828362-4828380	19	NZ_CP006871.1	8417047-8417065	2	0.895
NZ_CP006871_5	5.9|4828362|19|NZ_CP006871|CRT	4828362-4828380	19	NZ_CP006871.1	2423526-2423544	2	0.895
NZ_CP006871_5	5.9|4828362|19|NZ_CP006871|CRT	4828362-4828380	19	NZ_CP006871.1	3086991-3087009	2	0.895
NZ_CP006871_5	5.9|4828362|19|NZ_CP006871|CRT	4828362-4828380	19	NZ_CP006871.1	4110934-4110952	2	0.895
NZ_CP006871_5	5.9|4828362|19|NZ_CP006871|CRT	4828362-4828380	19	NZ_CP006871.1	7109306-7109324	2	0.895

1. spacer 10.1|7378593|49|NZ_CP006871|CRISPRCasFinder matches to position: 8691862-8691910, mismatch: 1, identity: 0.98

ctccggcgttcccgccgtgggggtttctgtttgcgcctgcggcgcgttg	CRISPR spacer
ctccggctttcccgccgtgggggtttctgtttgcgcctgcggcgcgttg	Protospacer
******* *****************************************

2. spacer 5.9|4828362|19|NZ_CP006871|CRT matches to position: 3364799-3364817, mismatch: 2, identity: 0.895

gctcggcccggcctgcgcc	CRISPR spacer
gcccggcccggcccgcgcc	Protospacer
**.**********.*****

3. spacer 5.9|4828362|19|NZ_CP006871|CRT matches to position: 3923227-3923245, mismatch: 2, identity: 0.895

gctcggcccggcctgcgcc	CRISPR spacer
gctcggcccgacgtgcgcc	Protospacer
**********.* ******

4. spacer 5.9|4828362|19|NZ_CP006871|CRT matches to position: 6651937-6651955, mismatch: 2, identity: 0.895

gctcggcccggcctgcgcc	CRISPR spacer
gctccgcccggccttcgcc	Protospacer
**** ********* ****

5. spacer 5.9|4828362|19|NZ_CP006871|CRT matches to position: 8417047-8417065, mismatch: 2, identity: 0.895

gctcggcccggcctgcgcc	CRISPR spacer
gcccggcccggccggcgcc	Protospacer
**.********** *****

6. spacer 5.9|4828362|19|NZ_CP006871|CRT matches to position: 2423526-2423544, mismatch: 2, identity: 0.895

gctcggcccggcctgcgcc	CRISPR spacer
gctcgtcgcggcctgcgcc	Protospacer
***** * ***********

7. spacer 5.9|4828362|19|NZ_CP006871|CRT matches to position: 3086991-3087009, mismatch: 2, identity: 0.895

gctcggcccggcctgcgcc	CRISPR spacer
gctgggcgcggcctgcgcc	Protospacer
*** *** ***********

8. spacer 5.9|4828362|19|NZ_CP006871|CRT matches to position: 4110934-4110952, mismatch: 2, identity: 0.895

gctcggcccggcctgcgcc	CRISPR spacer
gctcggcctggccggcgcc	Protospacer
********.**** *****

9. spacer 5.9|4828362|19|NZ_CP006871|CRT matches to position: 7109306-7109324, mismatch: 2, identity: 0.895

gctcggcccggcctgcgcc	CRISPR spacer
gctcgtccgggcctgcgcc	Protospacer
***** ** **********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	635772-635798	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NC_013545	Sinorhizobium meliloti plasmid pSmeSM11a, complete sequence	127230-127256	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	917333-917359	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NZ_CP019483	Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence	530580-530606	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NZ_CP019486	Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence	500122-500148	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	635439-635465	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	846616-846642	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	80094-80120	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NZ_CP021796	Sinorhizobium meliloti strain USDA1157 plasmid accessoryA, complete sequence	48887-48913	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NZ_CP021215	Sinorhizobium meliloti RU11/001 plasmid pSmeRU11c, complete sequence	39104-39130	4	0.852
NZ_CP006871_5	5.2|4828032|27|NZ_CP006871|CRT	4828032-4828058	27	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	400909-400935	4	0.852
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	443234-443260	5	0.815
NZ_CP006871_5	5.1|4827987|27|NZ_CP006871|CRT	4827987-4828013	27	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1209135-1209161	5	0.815
NZ_CP006871_5	5.3|4828077|27|NZ_CP006871|CRT	4828077-4828103	27	NZ_CP022999	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence	1061668-1061694	5	0.815
NZ_CP006871_5	5.3|4828077|27|NZ_CP006871|CRT	4828077-4828103	27	NZ_CP022999	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence	1063690-1063716	5	0.815
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	2863-2889	5	0.815
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	558802-558828	5	0.815
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NZ_CP032676	Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence	275559-275585	5	0.815
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NZ_CP013415	Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence	7414-7440	5	0.815
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4764015-4764041	5	0.815
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NC_013531	Xylanimonas cellulosilytica DSM 15894 plasmid pXCEL01, complete sequence	47209-47235	5	0.815
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NZ_CP026489	Streptomyces sp. 604F plasmid unnamed, complete sequence	40531-40557	5	0.815
NZ_CP006871_7	7.1|6641363|33|NZ_CP006871|CRISPRCasFinder	6641363-6641395	33	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	538427-538459	5	0.848
NZ_CP006871_7	7.1|6641363|33|NZ_CP006871|CRISPRCasFinder	6641363-6641395	33	KU958700	Streptomyces phage Chymera, complete genome	16890-16922	5	0.848
NZ_CP006871_5	5.3|4828077|27|NZ_CP006871|CRT	4828077-4828103	27	NC_022235	Sphingomonas sp. ERG5 plasmid pCADAB1, complete sequence	57296-57322	6	0.778
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NC_020894	Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence	6446-6472	6	0.778
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NC_017766	Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence	6446-6472	6	0.778
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NZ_CP023738	Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence	166819-166845	6	0.778
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NZ_LR134468	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 26, complete sequence	84046-84072	6	0.778
NZ_CP006871_5	5.8|4828317|27|NZ_CP006871|CRT	4828317-4828343	27	NC_008242	Chelativorans sp. BNC1 plasmid 1, complete sequence	53202-53228	7	0.741
NZ_CP006871_2	2.3|3723337|35|NZ_CP006871|CRISPRCasFinder	3723337-3723371	35	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	416850-416884	8	0.771
NZ_CP006871_7	7.1|6641363|33|NZ_CP006871|CRISPRCasFinder	6641363-6641395	33	NZ_CP023000	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence	606592-606624	9	0.727
NZ_CP006871_2	2.3|3723337|35|NZ_CP006871|CRISPRCasFinder	3723337-3723371	35	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	141768-141802	10	0.714
NZ_CP006871_2	2.3|3723337|35|NZ_CP006871|CRISPRCasFinder	3723337-3723371	35	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	141768-141802	10	0.714
NZ_CP006871_2	2.3|3723337|35|NZ_CP006871|CRISPRCasFinder	3723337-3723371	35	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	538808-538842	10	0.714
NZ_CP006871_2	2.3|3723337|35|NZ_CP006871|CRISPRCasFinder	3723337-3723371	35	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	99275-99309	10	0.714
NZ_CP006871_2	2.3|3723337|35|NZ_CP006871|CRISPRCasFinder	3723337-3723371	35	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	194829-194863	10	0.714

1. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

2. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NC_013545 (Sinorhizobium meliloti plasmid pSmeSM11a, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

3. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

4. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NZ_CP019483 (Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

5. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NZ_CP019486 (Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

6. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

7. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

8. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

9. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NZ_CP021796 (Sinorhizobium meliloti strain USDA1157 plasmid accessoryA, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

10. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NZ_CP021215 (Sinorhizobium meliloti RU11/001 plasmid pSmeRU11c, complete sequence) position: , mismatch: 4, identity: 0.852

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggtcgatgaaacgaccgcg	Protospacer
************** *.*******.* 

11. spacer 5.2|4828032|27|NZ_CP006871|CRT matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 4, identity: 0.852

gtcgcgacggtcgaaggaacgaccacc	CRISPR spacer
gtgacgacggtcgagggatcgaccacc	Protospacer
** .**********.*** ********

12. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 5, identity: 0.815

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
gtcacggcggacgaaggaacgatccgg	Protospacer
********** ***********.*   

13. spacer 5.1|4827987|27|NZ_CP006871|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.815

gtcacggcggtcgaaggaacgaccacc	CRISPR spacer
ggccttgcggtcgaaggaacgacctcc	Protospacer
* * . ****************** **

14. spacer 5.3|4828077|27|NZ_CP006871|CRT matches to NZ_CP022999 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence) position: , mismatch: 5, identity: 0.815

ccggtcacggtcccgaccgaagccacc	CRISPR spacer
accgtcacggtcgcgaccgaagccggc	Protospacer
 * ********* ***********. *

15. spacer 5.3|4828077|27|NZ_CP006871|CRT matches to NZ_CP022999 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-A, complete sequence) position: , mismatch: 5, identity: 0.815

ccggtcacggtcccgaccgaagccacc	CRISPR spacer
accgtcacggtcgcgaccgaagccggc	Protospacer
 * ********* ***********. *

16. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.815

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
ccggccggcgtcaccgcggtcgtcctc	Protospacer
 **.******.**************. 

17. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.815

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
ccggccggcgtcaccgcggtcgtcctc	Protospacer
 **.******.**************. 

18. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NZ_CP032676 (Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence) position: , mismatch: 5, identity: 0.815

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
acgaccggcgccaccgtggtcatcggc	Protospacer
****************.****.**   

19. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NZ_CP013415 (Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence) position: , mismatch: 5, identity: 0.815

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
gcgtccggcgcctccgcggtcgtcgct	Protospacer
.** ******** *********** * 

20. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
accgccggcgccaccgcggtcgttctc	Protospacer
** .*******************.*. 

21. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NC_013531 (Xylanimonas cellulosilytica DSM 15894 plasmid pXCEL01, complete sequence) position: , mismatch: 5, identity: 0.815

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
ctgcccggcgccgccgcggtcgtccag	Protospacer
 .* ********.************ *

22. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NZ_CP026489 (Streptomyces sp. 604F plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
gagcccggcgcccccgcggtcgtcgcg	Protospacer
. * ******** *********** **

23. spacer 7.1|6641363|33|NZ_CP006871|CRISPRCasFinder matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.848

gccggc--ctccttggcgggcgccggcggggccgg	CRISPR spacer
--cggcagcccctcggcgggcggcggcggggccgg	Protospacer
  ****  *.***.******** ************

24. spacer 7.1|6641363|33|NZ_CP006871|CRISPRCasFinder matches to KU958700 (Streptomyces phage Chymera, complete genome) position: , mismatch: 5, identity: 0.848

-gccggcctccttggcgggcgccggcggggccgg	CRISPR spacer
cggcggcc-gcttggcgggcgcgggcggggtcgg	Protospacer
 * *****  ************ *******.***

25. spacer 5.3|4828077|27|NZ_CP006871|CRT matches to NC_022235 (Sphingomonas sp. ERG5 plasmid pCADAB1, complete sequence) position: , mismatch: 6, identity: 0.778

ccggtcacggtcccgaccgaagccacc	CRISPR spacer
ccggtcacgctcccgaccaaagcgctg	Protospacer
********* ********.****  . 

26. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NC_020894 (Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence) position: , mismatch: 6, identity: 0.778

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
acgaccggcgccaccgcggtgacggcc	Protospacer
******************** ..  * 

27. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NC_017766 (Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence) position: , mismatch: 6, identity: 0.778

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
acgaccggcgccaccgcggtgacggcc	Protospacer
******************** ..  * 

28. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NZ_CP023738 (Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence) position: , mismatch: 6, identity: 0.778

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
gcgatcggcgccaccggggtcgtcaac	Protospacer
.***.*********** *******   

29. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NZ_LR134468 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 26, complete sequence) position: , mismatch: 6, identity: 0.778

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
gtgaccagcgccgccgcggtcgtccgc	Protospacer
..****.*****.************  

30. spacer 5.8|4828317|27|NZ_CP006871|CRT matches to NC_008242 (Chelativorans sp. BNC1 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.741

acgaccggcgccaccgcggtcgtcccg	CRISPR spacer
gcgaccggcgccaccgcggtggagaac	Protospacer
.******************* *     

31. spacer 2.3|3723337|35|NZ_CP006871|CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 8, identity: 0.771

ccccgtctcccgctcgggccggccg-----ctccgcacgc	CRISPR spacer
ccccgcctcccgctcggcccggccggcttcctcca-----	Protospacer
*****.*********** *******     ****.     

32. spacer 7.1|6641363|33|NZ_CP006871|CRISPRCasFinder matches to NZ_CP023000 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence) position: , mismatch: 9, identity: 0.727

gccggcctccttggcgggcgccggcggggccgg	CRISPR spacer
tccggcctccttcgcggccgccggcgcctcgct	Protospacer
 *********** **** ********   *   

33. spacer 2.3|3723337|35|NZ_CP006871|CRISPRCasFinder matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.714

ccccgtctcccgctcgggccggccgctccgcacgc	CRISPR spacer
cgcgccggcccgctcgggccggcagatccgcacca	Protospacer
* *  .  *************** * *******  

34. spacer 2.3|3723337|35|NZ_CP006871|CRISPRCasFinder matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.714

ccccgtctcccgctcgggccggccgctccgcacgc	CRISPR spacer
cgcgccggcccgctcgggccggcagatccgcacca	Protospacer
* *  .  *************** * *******  

35. spacer 2.3|3723337|35|NZ_CP006871|CRISPRCasFinder matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 10, identity: 0.714

ccccgtctcccgctcgggccggccg---ctccgcacgc	CRISPR spacer
ccccgtctcccgctccagccggccgagatcgagta---	Protospacer
*************** .********   ..  *.*   

36. spacer 2.3|3723337|35|NZ_CP006871|CRISPRCasFinder matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.714

ccccgtctcccgctcgggccggccgctccgcacgc	CRISPR spacer
cgcgccggcccgctcgggccggcagatccgcacca	Protospacer
* *  .  *************** * *******  

37. spacer 2.3|3723337|35|NZ_CP006871|CRISPRCasFinder matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 10, identity: 0.714

ccccgtctcccgctcgggccggccgctccgcacgc	CRISPR spacer
ccccgtctcccgctccagccggccgaggtcgagga	Protospacer
*************** .********   .  * * 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	4911719 : 4918481	8	Mycobacterium_phage(100.0%)	integrase,transposase	attL 4909119:4909133|attR 4925341:4925355
DBSCAN-SWA_2	5941542 : 5966853	28	Streptomyces_phage(100.0%)	tail,portal	NA
DBSCAN-SWA_3	7874777 : 7881696	8	Mycobacterium_phage(16.67%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP006871|4911719:4918481|DBSCAN-SWA
CTCACGTGGTGAGTTTCGCAAGCTTCTTGTAGCAGGCCAAGGCAGCCGCGAGGCCGAGGAACGCGAGAAAGTGGTTGCCCTTTCGCTCGAATCGGACGGTGAGCCGGCGGTAGCCGAACAGCCAGGAGATCGACCGCTCGATCTTCCAGCGGTGGCGGCCGAGCCGTTCGCCGGACTCGATTCCCGGGCGCGCGATCCGCGCGACGAGCCGCCTGCCGCGGAGCCATGTGAGGTGATCGGCGGAGTAGTAGGCCTTGTCCGCGCGGATCTTGGCCGGCCGTCTTCGGCGCAGTCCGCGCCTTCTCACCTTCCCAACTTGCCCCACCGGGTGGGTTGGCCGACGGGCGTCAGGTCACCTCATGACCTCAGGTGACAAGGCACCTTCCCCAGCCGCGAGGGATGGGGGCTCTATCGTGCCGTCGGCTGGTGGAGCCAGGGCGCGCTGGTGGCCCAGAAGATGACGTCGGCTCCGAGGGTGTTCGTGCCGAAGTCGGTGAACTCCTTCCGGGTGTACGGCTTCTTCGTCTTGGGGTTCTCGTACTGGAAGTCGGGTTCCTGTACGGCCATGGCCACCACGGGGAGCTGCCCCCGGTACTTCTTGAAGAAGGGGTACGAGTTCTCCATCTGCGCCGGGCGGTCCGGCAGGATGTCCGGTCCCCCCAGGCCGATTCCGTGCGCCTTGGCAAACTCGAAGGTGCGGCTCATGTACTTGCGGCTGTTGTTCCATTCACCGGGCCAGAAGTTGACGTACTGGATGAACGGCGTCTTGGTGAAGACCTTCTTGCCGTAGGCCATGTTGTCGAGTTCTGCCTTGAAGTAGGCGTCGTCGCTGTAGCCGGTGTGGTCCTTCTTGGTGTCCACCTCGGTAGCGGTTTCCGGCAGGTTCACCCCAGCGAGGCGACCGTCGAACCGCTGTGACATCGCCTTCAGCAGCTGCTGGAAACGACCCCGCACCTGCGGGTTCCATTGCGCCGCGACCGCCCCGGGCTCACCGGGGCCGAGGCCGTTCTCGTTCTTTGTCGGAGCCGCGCCTCCCTTGTACTCCGGATCCTTCAACAGATAGTCCGGGAGCCTCGCCGGCAGCGCGAAGAACCGGTCCTGGACCTGGATGAACAGCTTCTTGTGGCGGGACTGCAGAACGTTCAGCGCCCGGTCGATCTCAGAGAAGTCGTACTGATTCCTCTCCCGCTCCAGCGCCTTCCACGGCACCACCAGCTGCACGCCGGCGACATCGGGGCGATCGATCAATGGCATCACATTTGCGTTCCATCAAGTCCCTCTCCCAACTGCGTGGACAACAAAAGCCACATTAGGGGATGAACTGGGTGCACTCGCAGGCGGCACTCCGATGCCCCACCGTACGCCTCAACTCCCGTGCCGCGCACCCGCGTACCGCCCCGCGGAGCCCGCCCAACCACCTCCCCGGCGCCCCCTCCGAGGCACCCCACCCACCACCCGGACATGCCAAATGCACCGCGGCACGGCGATGGGGTAGAGTGTGCGACGAAGCTCCGCCTCCAGACTGGTTCACTCCAGCCCGGCGGTGTTACGCGGGTGTAGTTTAATGGTAGAACATGAGCTTCCCAAGCTCAGAGCGCGGGTTCGATTCCCGTCACCCGCTCCATAACGAAGGCCCAGGTCAGAGACTTGGGCCTTCATTGCTGTCTAGACCATTCTCGGGCCAACCAGCCCCCCACCAGCCCCATCTGCCAGCCGAGGCGTAAGCTTCACCCACTCCCACACCGAGCCAGGCACCTTGAGAGTCGACCTTCTCAAATAGCGAGACGCATTTTCTGTGACTTGGGTCACTCACTCCTGAGGTGTCGCGAGATTACGGATGCAAAATGGGCTCTTGGCAAGGGAGTTCGTCTGGCCCCTGCCCGCGCTCCGGACGGCGAACGCACTCCGCTTAAAACACAGCGCAGTGTAGGCAGGACCGTTCAGCTACTGAACGGTCCTGCCTACACTGCGCATTGCCCTCTGGGTTGGGGAAAACCGACGCCTTAGAGGGTGTCTCACGTGGTGAGTTTCGCAAGCTTCTTGTAGCAGGCCAAGGCAGCCGCGAGGCCGAGGAACGCGAGAAAGTGGTTGCCCTTTCGCTCGAATCGGACGGTGAGCCGGCGGTAGCCGAACAGCCAGGAGATCGACCGCTCGATCTTCCAGCGGTGGCGGCCGAGCCGTTCGCCGGACTCGATTCCCGGGCGCGCGATCCGCGCGACGAGCCGCCTGCCGCGGAGCCATGTGAGGTGATCGGCGGAGTAGTAGGCCTTGTCCGCGCGGATCTTGGCCGGCCGTCTTCGGCGCAGTCCGCGCCTTCTCACCTTCCCAACTTGCCCCACCGGGTGGGTTGGCCGACGGGCGTCAGGTCACCTCATGACCTCAGGTGACAAGGCACCTTCCCCAGCCGCGAGGGATGGGGGCTCTATCGTGCCGTCGGCTGGTGGAGCCAGGGCGCGCTGGTGGCCCAGAAGATGACGTCGGCTCCGAGGGTGTTCGTGCCGAAGTCGGTGAACTCCTTCCGGGTGTACGGCTTCTTCGTCTTGGGGTTCTCGTACTGGAAGTCGGGTTCCTGTACGGCCATGGCCACCACGGGGAGCTGCCCCCGGTACTTCTTGAAGAAGGGGTACGAGTTCTCCATCTGCGCCGGGCGGTCCGGCAGGATGTCCGGTCCCCCCAGGCCGATTCCGTGCGCCTTGGCAAACTCGAAGGTGCGGCTCATGTACTTGCGGCTGTTGTTCCATTCACCGGGCCAGAAGTTGACGTACTGGATGAACGGCGTCTTGGTGAAGACCTTCTTGCCGTAGGCCATGTTGTCGAGTTCTGCCTTGAAGTAGGCGTCGTCGCTGTAGCCGGTGTGGTCCTTCTTGGTGTCCACCTCGGTAGCGGTTTCCGGCAGGTTCACCCCAGCGAGGCGACCGTCGAACCGCTGTGACATCGCCTTCAGCAGCTGCTGGAAACGACCCCGCACCTGCGGGTTCCATTGCGCCGCGACCGCCCCGGGCTCACCGGGGCCGAGGCCGTTCTCGTTCTTTGTCGGAGCCGCGCCTCCCTTGTACTCCGGATCCTTCAACAGATAGTCCGGGAGCCTCGCCGGCAGCGCGAAGAACCGGTCCTGGACCTGGATGAACAGCTTCTTGTGGCGGGACTGCAGAACGTTCAGCGCCCGGTCGATCTCAGAGAAGTCGTACTGATTCCTCTCCCGCTCCAGCGCCTTCCACGGCACCACCAGCTGCACGCCGGCGACATCGGGGCGATCGATCAATGGCATCACATTTGCGTCGAAATCACCGATGGAGGCGTAAAGATAGTTCTTCGCCTTCTTTCCGGGCACTGCGGCGGAAGCCTTACCGGACACCGGAGCGGGAGCCCCAGAGGCCACCGCGGCCACGCCCGTCAGGCCCATCGCCACGAGAATTCCGACACCGACAGCAATTCGCTTGGTCGCCATGAACCCCACGGTGCAGCACAGTTGTGAGAGGAATGTAAGAAGGCCGGACATTCCTCCTGACCAAGAGGACGTCTCACGTGGCGAGTTGCTGATGCGGGATGATGCTGCACTGTGGCTGTTGATCTGTCCCGCCGGCTTGTGCCGTACGGGTTGTGGGAGTTGGCGGCACCGCTGCTGCCGAAGTTCACGTCCCGCCCGCAGGGCGGGGGTACGAGTCCGGTGGACGAGCGGGCGCTGTTCACGGCGGTGGTGTACGTGCCGACCAGCGGTTGCGCCTGGCGCCGTCTTCCGCCGACGTTCGGCGTCTCCCCGGCAACAGCGCACCGCCGGTTCACGGCGTGGACCGAGGCCGGGCTGTGGCGCCGACTGCACCGGGCAGTCCTGGATGAACTCGGCGCCCGGGGCGAGCTGGACTGGACCTCAGCAATCATCGACGCAGCCTCCGTCCGCGCGAAAAGGGGGGTTTGCTGACCGGGCCGAACCCGGTCGATCGCAGCAAGAAGGGCAGCAAATTACATGTCCTGTCCGAAGCTCAGGGCGTCCCACTGGCCCTCGCGGTCTCCGGCGCGAACATGCACGACAGCCAGGCGTTCAAGCCACTGATCCTCGGCATACCCGCCATCCGCTCACGGCGCGGACTGCGCCGAAGACGGCCGGTCAAGATTCGCGCGGACAAGGCGTACTACTCTGCCGATCACCTCACATGGCTCCGCGGCAGGCGGCTCGTCGCGCGGATCGCGCGCCCGGGAATCGAGTCCGGCGAACGGCTCGGCCGCCACCGCTGGAAGATCGAGCGGTCGATCTCCTGGCTGTTCGGCTACCGCCGGCTCACCGTCCGATTCGAGCGAAAGGGCAGCCACTTTCTCGCGTTCCTCGACCTCGCGGCAGCACTGACCTGCTTCAAGAAGCTTGCGAAACCCACCACGTGAGACACCCTCTTAGCCGGAGTGCTTCCGCTCCTCCGCCTGAAGTTGCTCGGCTGCCTCCCGACGCTGCTGGCGCACCTCGGCGTCGATGCTCTTCGCAAGCTTGCGCTGGTGCTTCTTCTTGGAGTGCTGGTAGATCAGCTGAGCCTTGGGGCTGGACTGGCCCGCGCGGACCATGAGGTCCTTGAGCTTCGCGCCGGAGTCGGCCGCGAGGGTGTTACCGGTGTGGCGCAGATCGTAGAAGCGGAAGTTGTCCGGCAGTCCCACCGCGATGCGTGCCTTGCGCCACTTGCGCCCGAAGGAGGACCGTCGCAGAGCAGCCCCGCGCTCGCCCACGATGAGGAGTCCGTCCGGTTCCTTCTCGGCGAACCACTGAAGGTGGCGACGCAGCTCGGGCACCAGGAAATCGGGCAGGTACACCGCACGCTTGCCCGCTCGCGACTTCGGATCGCCGATCACCTTCTTGCCGTTGGTCAGCTCCGGCGCGGCGCGCCTGATCCACACCACGCCCTCGTCGACGTCGATGTCGCTGCGGCGCAGCTCGGCGAGTTCTTCGGGACGCAGGGACGCGAAGGCCCCGAGGAAGATCATGATGCGCCAGCGTGGTCCGATGGCTTCGGCCAGGGCATAGACCTGTTCGACCTCGGCGACGTCGCGTTCGTCGGCCTCCTCCTTGCCGGCGCCCTTGATACGGCACGGGTTGCTCTTGAGGAGATCGTCGTCGACCGCGGTCTGAAGGATGGCCTTCAGCAGGCGGTAGGACTTGGCCACTGTCGTCTTCGCACCGTTGGTCGCCTTCAGCCGCTCGGCTCGCGCTCAGGGCGTCCCACTGGCCCTCGCGGTCTCCGGCGCGAACATGCACGACAGCCAGGCGTTCAAGCCACTGATCCTCGGCATACCCGCCATCCGCTCACGGCGCGGACTGCGCCGAAGACGGCCGGTCAAGATTCGCGCGGACAAGGCGTACTACTCTGCCGATCACCTCACATGGCTCCGCGGCAGGCGGCTCGTCGCGCGGATCGCGCGCCCGGGAATCGAGTCCGGCGAACGGCTCGGCCGCCACCGCTGGAAGATCGAGCGGTCGATCTCCTGGCTGTTCGGCTACCGCCGGCTCACCGTCCGATTCGAGCGAAAGGGCAGCCACTTTCTCGCGTTCCTCGACCTCGCGGCAGCACTGACCTGCTTCAAGAAGCTTGCGAAACCCACCACGTGAGACACCCTCTTAGCCGGAGTGCTTCCGCTCCTCCGCCTGAAGTTGCTCGGCTGCCTCCCGACGCTGCTGGCGCACCTCGGCGTCGATGCTCTTCGCAAGCTTGCGCTGGTGCTTCTTCTTGGAGTGCTGGTAGATCAGCTGAGCCTTGGGGCTGGACTGGCCCGCGCGGACCATGAGGTCCTTGAGCTTCGCGCCGGAGTCGGCCGCGAGGGTGTTACCGGTGTGGCGCAGATCGTAGAAGCGGAAGTTGTCCGGCAGTCCCACCGCGATGCGTGCCTTGCGCCACTTGCGCCCGAAGGAGGACCGTCGCAGAGCAGCCCCGCGCTCGCCCACGATGAGGAGTCCGTCCGGTTCCTTCTCGGCGAACCACTGAAGGTGGCGACGCAGCTCGGGCACCAGGAAATCGGGCAGGTACACCGCACGCTTGCCCGCTCGCGACTTCGGATCGCCGATCACCTTCTTGCCGTTGGTCAGCTCCGGCGCGGCGCGCCTGATCCACACCACGCCCTCGTCGACGTCGATGTCGCTGCGGCGCAGCTCGGCGAGTTCTTCGGGACGCAGGGACGCGAAGGCCCCGAGGAAGATCATGATGCGCCAGCGTGGTCCGATGGCTTCGGCCAGGGCATAGACCTGTTCGACCTCGGCGACGTCGCGTTCGTCGGCCTCCTCCTTGCCGGCGCCCTTGATACGGCACGGGTTGCTCTTGAGGAGATCGTCGTCGACCGCGGTCTGAAGGATGGCCTTCAGCAGGCGGTAGGACTTGGCCACTGTCGTCTTCGCACCGTTGGTCGCCTTCAGCCGCTCGGCTCGCCAGACGCGCACATCCGCCGGTTGGATCTCGTCCAGGTCCCATGTGCCGAACGTGGGCGCGATGTGCCTGGTGAGCAAGCGTGTGTACAGGTCCTCGGTGGTCGCTGCGAGGCCGCGCTCGTTGACCCACTTCCTCGCGAAGTCCTCGAAGTTGACGGCGCCGGCGTCGGGGTCGGCCCAGTGCTTGCGCTCGATATCGGCCTGGGTCAGTGCGAGCCAGGTCGTTGCCTCCGTCTTGGTCTCGAACGTCTTCGGCGCATAGCGCCGCTTGCCGTCCGGAGCCCAGTAACGGGCCTGGAAGCGCCCCGACTCGGTCTGGCGCACACTGCCGAATTCACGCCGCCGCTGCGGCTTTCGCGCCATCAG

Protein sequences of DBSCAN-SWA_1

>NZ_CP006871|4911719:4918481|4912126_4912975_-|WP_063789844.1|DBSCAN-SWA
MMPLIDRPDVAGVQLVVPWKALERERNQYDFSEIDRALNVLQSRHKKLFIQVQDRFFALPARLPDYLLKDPEYKGGAAPTKNENGLGPGEPGAVAAQWNPQVRGRFQQLLKAMSQRFDGRLAGVNLPETATEVDTKKDHTGYSDDAYFKAELDNMAYGKKVFTKTPFIQYVNFWPGEWNNSRKYMSRTFEFAKAHGIGLGGPDILPDRPAQMENSYPFFKKYRGQLPVVAMAVQEPDFQYENPKTKKPYTRKEFTDFGTNTLGADVIFWATSAPWLHQPTAR
>NZ_CP006871|4911719:4918481|4916104_4916893_-|WP_079164278.1|integrase|DBSCAN-SWA
MKATNGAKTTVAKSYRLLKAILQTAVDDDLLKSNPCRIKGAGKEEADERDVAEVEQVYALAEAIGPRWRIMIFLGAFASLRPEELAELRRSDIDVDEGVVWIRRAAPELTNGKKVIGDPKSRAGKRAVYLPDFLVPELRRHLQWFAEKEPDGLLIVGERGAALRRSSFGRKWRKARIAVGLPDNFRFYDLRHTGNTLAADSGAKLKDLMVRAGQSSPKAQLIYQHSKKKHQRKLAKSIDAEVRQQRREAAEQLQAEERKHSG
>NZ_CP006871|4911719:4918481|4917314_4918481_-|WP_037633555.1|integrase|DBSCAN-SWA
MMARKPQRRREFGSVRQTESGRFQARYWAPDGKRRYAPKTFETKTEATTWLALTQADIERKHWADPDAGAVNFEDFARKWVNERGLAATTEDLYTRLLTRHIAPTFGTWDLDEIQPADVRVWRAERLKATNGAKTTVAKSYRLLKAILQTAVDDDLLKSNPCRIKGAGKEEADERDVAEVEQVYALAEAIGPRWRIMIFLGAFASLRPEELAELRRSDIDVDEGVVWIRRAAPELTNGKKVIGDPKSRAGKRAVYLPDFLVPELRRHLQWFAEKEPDGLLIVGERGAALRRSSFGRKWRKARIAVGLPDNFRFYDLRHTGNTLAADSGAKLKDLMVRAGQSSPKAQLIYQHSKKKHQRKLAKSIDAEVRQQRREAAEQLQAEERKHSG
>NZ_CP006871|4911719:4918481|4911719_4912043_-|WP_063745822.1|transposase|DBSCAN-SWA
MGQVGKVRRRGLRRRRPAKIRADKAYYSADHLTWLRGRRLVARIARPGIESGERLGRHRWKIERSISWLFGYRRLTVRFERKGNHFLAFLGLAAALACYKKLAKLTT
>NZ_CP006871|4911719:4918481|4914140_4915166_-|WP_063745823.1|DBSCAN-SWA
MATKRIAVGVGILVAMGLTGVAAVASGAPAPVSGKASAAVPGKKAKNYLYASIGDFDANVMPLIDRPDVAGVQLVVPWKALERERNQYDFSEIDRALNVLQSRHKKLFIQVQDRFFALPARLPDYLLKDPEYKGGAAPTKNENGLGPGEPGAVAAQWNPQVRGRFQQLLKAMSQRFDGRLAGVNLPETATEVDTKKDHTGYSDDAYFKAELDNMAYGKKVFTKTPFIQYVNFWPGEWNNSRKYMSRTFEFAKAHGIGLGGPDILPDRPAQMENSYPFFKKYRGQLPVVAMAVQEPDFQYENPKTKKPYTRKEFTDFGTNTLGADVIFWATSAPWLHQPTAR
>NZ_CP006871|4911719:4918481|4916855_4917305_+|WP_045788075.1|transposase|DBSCAN-SWA
MATVVFAPLVAFSRSARAQGVPLALAVSGANMHDSQAFKPLILGIPAIRSRRGLRRRRPVKIRADKAYYSADHLTWLRGRRLVARIARPGIESGERLGRHRWKIERSISWLFGYRRLTVRFERKGSHFLAFLDLAAALTCFKKLAKPTT
>NZ_CP006871|4911719:4918481|4913733_4914057_-|WP_063745822.1|transposase|DBSCAN-SWA
MGQVGKVRRRGLRRRRPAKIRADKAYYSADHLTWLRGRRLVARIARPGIESGERLGRHRWKIERSISWLFGYRRLTVRFERKGNHFLAFLGLAAALACYKKLAKLTT
>NZ_CP006871|4911719:4918481|4915277_4916094_+|WP_106966019.1|transposase|DBSCAN-SWA
MAVDLSRRLVPYGLWELAAPLLPKFTSRPQGGGTSPVDERALFTAVVYVPTSGCAWRRLPPTFGVSPATAHRRFTAWTEAGLWRRLHRAVLDELGARGELDWTSAIIDAASVRAKKGGLLTGPNPVDRSKKGSKLHVLSEAQGVPLALAVSGANMHDSQAFKPLILGIPAIRSRRGLRRRRPVKIRADKAYYSADHLTWLRGRRLVARIARPGIESGERLGRHRWKIERSISWLFGYRRLTVRFERKGSHFLAFLDLAAALTCFKKLAKPTT

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4909119:4909133	attL	NA	NA	NA	NA
WP_063745822.1|4911719_4912043_-|transposase	transposase	NA	NA	NA	NA
WP_063789844.1|4912126_4912975_-	hypothetical protein	NA	NA	NA	NA
WP_063745822.1|4913733_4914057_-|transposase	transposase	NA	NA	NA	NA
WP_063745823.1|4914140_4915166_-	hypothetical protein	NA	NA	NA	NA
WP_106966019.1|4915277_4916094_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_079164278.1|4916104_4916893_-|integrase	site-specific integrase	A0A1D8EZV4	Mycobacterium_phage	3.2e-28	35.5
WP_045788075.1|4916855_4917305_+|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
WP_037633555.1|4917314_4918481_-|integrase	site-specific integrase	A0A097BXY4	Mycobacterium_phage	4.5e-50	35.3
4925341:4925355	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP006871|5941542:5966853|DBSCAN-SWA
CTCACGGGGTCTTCGGGGCCCAGTCGGCAGGGAGGCCGTATCCCCCGGCCCAGGTCTTTCCGTAGACCTCTGCATCGGTGCCGATGGGTACACCGAATAGATCCATGCGGACCGTCTTCGCGACTTCCCGGGCAATGTCGGCTGCCTCTGCCGCCGGGGCCGTGCCCAGCACCTCGTCATGCACCCACAAATTCAGATACTGCGTCAGACCCTTCGCGTGGAGATCCAAGAGCGCCTGACCCATGGTGTCCCGGGCTGTGGACTGGCAAAGGTAGGCCACACCCTTATAGAGCGCATTCCGATCGAGAACCAGCCTTCGCCCAGAAGGAGTTCGGATCTCGCACTCATTGCTCAGGGCGTGGCGCTGAAGGCCGCGGGCCCATCGGCGAATTCCCGGGTAGGCCCGCACATAGCGGGCCAGAGTATCCCGCATGACTGAAACGGGAAGTCCGGTCTGCCTCGCCAGTGTCGCCGCGCCGCCCTGGTACGACGTTCCCAGGCCCGCGATTTTCGCCAGACCTCGTTGGTGCTTGGTGAACGCGGGCCCGAACATGAGCGTGGCCGTGTGGTCGTGGAGGTTGCGGCCGTCACGGATGGCCTGGCACATGCGCGGTTCCTGCGACAGGGCCGCCAAGACAACCAATTCCACACTGGATTGATCCACGCTGAAGTAGGCGGCACCGGATTCCGCCACGACGCTCCGGCGGATTTCCCAACCCTTGGAGGGAAGTTGTTGGAGCGGCGGGTCCGACACGGAGGCCCGCCCCGTCTTCGCCCCAAGGGTGTTGATCTTCGGGTGGATACGGTCCTGGGCGTCTCGGTTCGCGAGCATGGCCACGGCGTACGACGTGCGCCACTTGGACGCCCGCTTGGCGCGAAGGACCGCGTCCGCCAACGGGTTGGGCGTGCGGACCTGCAACCGCTCCCACTTGTCGCTCAGGTCCGCCAGGGGCAATAGCACCTCCTTGGCCACCGACGGGGCCCCGGAACCGGTCGTCTCCTCCCAGCTCTCTCCCATGCCCTGGAGCGCAGCCACCACCTGGCGATCGGAGTTGACGTTCTCGACGCCGTACCGGGCCGCCCTCGCGGAGTGCGTGGCCGCCTGCTCCTGAAGTCGGTTCACCAGGCCCTCCGTGTACGGAACGTCCAGGAGCATGCCGCGACGCTCCATGGCCGCACAGATGGCCATGAGCTGGTGCTCGTACTCCACCAGCGTGTCCGGAATGCCGTGGCGGACCAGCTCCTGTTCCAGGTGGGGGCGAAGGCGGGCGGCCAGGAGGACGTCCAGGCCGGCGTAGCGCTGGTAGACCTCGTCCTGGTAGGGGACCTGAGCCCAGCCGGTTTCCTTGGTCAGGCCGTAGGACCGGAACACCCGGGTAAGGCCGGCCTGCGTGTCCGGCGCTGCCGGGTCCACGTACCAGGCGGACAATGGCTTGAGGCTGACGCCTACTCCCCCTTCGAAATCCTGCCTGCTATCGGAGAGATGGGCCAGGATCTTGGTGTCCCGCACACGCGGTGCGACGGTCTCCAGCGGTGAGACGCCGTGGCGGTCCAACACCAACAGGTCGTAGGCCGCGTTGTGGATCACCAGCTCCGGGCATCGAGTCACCACTGTGCGGGCCAAGTCCATGAAGGCCGGCCCGCGTTCGACCGGAACGACAAACGCCGTGTCCGCGGTGCCGTACTGGACGGTGCGGAGTCGGTGACCGGTGCTGAACGTATCCAGACCAGTGGTCTCGGTATCCATGGCGAGTGACCGTGGCTGGTGTGTGGTCAGCCAGTCCCGGGCCTGGCGTACGTCGTCCTCCGTCTCCAGGGCATGGATGGTGGTCTGGTCGCCGGCCAGTTGGTGGCGGTGGGTGATCAACGCGGGCTCCATGGTGGTGCGTCGGCCGCCGGGGCACCCGCTCCGTGGCATGCGAAGGGGGCCGCCCGGTCGGGACGGGCCCCTGTACGCGCTTACGCGGCGCTTCTGGGCTGGCCGAAGATGTCTGCGGTGCCCGCATCCACTGGGGCCCGTGACACCGAACGGCAGTCCGCCAAGTTCGCCAGGACCGGCGTCCCGTTCACCTTGGACTCCCGCACACCGGGGAAGGTGCGAAGCGCGTCGTAGAACTTGTTGCGGGTCATGGGATGGCGGATGCCGCACTCCTCCACCCACGTTCGGTAGCGCTCCCACGTGGCCGTGCGGGGAACGTGCGCGCCCTCCTGGGCCACGTACTCCTCCCCGATGAACCCGGCCAGGGGGTGGCTGGTGTCGCGGTAGTGGGCGGTACGCCGCTCCACCGCATCCGGGAAGGCCAGGCCCCGGCCGGCGGTGTGCTCCCGATACCAGGCCACGGCCCCGCGTACCGCCCACGCCGCGATGCCCTCGCGCTCCGACGCCAGCGTCGCCTTCAGCCGTTTGTCCTCCCGCCCGCGGAAATCTTGCATCCAGGGGACGACCCGAACGCGCTGCCACAGCGCTTGGTCGGTCGCGTCCACGTCCGGCGCGTAGTTGGTGTCCACCTGGACCAGGCACACCGGCCGAAACGTCAGCTCCTCCCGGGCGTAAACGCCCCGGGCCGTGATCGTCTGGTCTCCGGTGACCGCTTTCATCAGCGCCTGATCAAGCGGCATGTTCGCTGGCCACTCGGAGGAGATCACCAGGCGCCGGCCGCGCAGGCTGACCACGTCCGCTCGGGGCCCGCCCGACTCCCGCCGCTTCTGGAAGAGCGCGGGGTCAGCCCGCTTCGTGATCCCCCGGAATACCCGCTCCAGGGTCTCCGTGAACGTGGTCTTGCCGTTCGTTGTGGGGCCGACGTGCATCACAAAGCAGCGTTCGACGCCATACCCGGTGATCCCATAACCGGTGAGCACCTGAAGGAAGTTGGGCATGCCGGGCGCGTGAGGGTGGCACTCCGCCAAGAACCTTTCCCAGCGGGGCGCTTGGGCGTCCGGGCGGTAGTCCACGTCCAGGACGGCCGTGTTCATGTCCGCCGGATCGTGCGGCCGGGTCTGGCCCGTGCGCAGATCCACCACCGTGTTCTTGAACGCCAACAGGTTCGGGTCTGCGTCGAACCGGTCGGCCGTGGCGTACACGCCGGGGATGGAAGCCAGCATCTCCACCATGGCCTTGACCCGCCCGGAGTCCTGCGACTTCAGCGCCCACCGGGCGCGCTTCTCCGGATCATGGCCGGTCTCACCCTCCAGTGCGTGAATCACCGCCCGCACGTCCGCGTACAACGCTTCCTTCGGAATGAGTTGCCAGTGCGTCCCATGCCACTTGTAGACGCCGATGCCGGGCACCATGCGCACGTGGCCGCCGAGTTGGCGGTACAGCCTTGTGGCGTTGCCCAGATCAGTAAGCGGCATGGGCCTGGGCTCGTCCGTGCCGACGGCGGACGTGTCCGGTTCGGGCCCCACGTCCAGGACGTGGAGCGGTGCCCGGCGGACGGCCGCGTGGAGGTGGCCGGGGAATGCCTCCGGGTCGCGAGCCCGCCAGTCGGTCAGGTCGTCCCCGGGCGTCGGGATCTCCAGTTTCCGGACCATGACCCCGGCCTGGACCAAGGCGTCCGCCAAGGCATCGGTGAAGGCGGCCCCGGCGGTGTCCCGGTCACCGGCCAGCACCACGTCTCGGTCTCCCAGCCCCGCAGCCAGCTCTGCGACGAGCGCGGCGTTGCGGGCCAGGCCCGCACCCCGGACCATCACCACGTCATATCCGACGGCAACGCCTGTCAGGCCGTCGCCGGGGCCTTCGGTGATCAGCACCGTGGCATAGCCGGAATTGGCGCGTAGGACGCCGTACTTGGCCCACGCCGAGCCATCCGGGGAGACGATGGACAGCCACCGGGCCGGGCAGTGCCCGGTCAGGTCCCGGCCCTGGAGGCCCCGGGGCCTGCCGTTGAAGTCGCACAGCGGGACCGTCAGGCGAGGGTGGCGCAGGTAGCCGGTGGAGCGGTAGGGGAACCGGTCGTCCAGGCCCGGGTAGTCCAGGCCCAGGCCGAGGTCCACCGCGCGCTCCGCGTCGAGGCCGAAGCGTTCGGCCACGTAGTCCCGGGCTTCCGAGTGCTCCGGGTCCAGGAACGCCACGTTCGTGGTGTCCACGTACTGGGCCAGAGCCGCCAGGGCTCCGGCGTCCAGGACACCGGGCACCGGCTTGGCCGACGCCTTCACGCCCGCTCCCGGGGTCCAGTCGAACAGGTCCGCCGGCCTCATGCCCAGCGCCGCCAGGATGACGTCACGGGGGCATCCAGCCCAGCAGCGCACCAGGAGCCGCCCGTCCTCCTTGAGACGAAAGAACAGGCTGGGTCGCTGGTCGTCATGGACGGGGCAGGGAACGCCGTACTCCCCGCGCTCCTCCACCACTTCCGAGAAGCGGACCAGAAACTGGGCCAAGTCCTTCGTGCGCAACGTCTCTCCTCCAACGCAAAGCGGGCGTGTCCGGCCCCATGCACTGGGGTCCGTGACACGCCCGCTTCCGGGAGGTCAGTCGAGATGGCGGAGGGCTTGGAGGACGCGCCCGAACGTGATCAGGTCCATGACCGCGTAGGCGTCCTCTACGCGTCGACGCGGGGCCTTCACCACGGCCACGCCGTACGGGAAACCGGCGTGTTCCGCCTCTCGGTTTGCCTGGCGTACGTAGTCGGCCAGACGGATGGAACGCTCCGCCTTGCACTCGATGACGAACGGCTGGGCGTGGAGGTCTCCCACGTCCTTGGCGCCGGTCTGTGCCGGCCGGGTGATGTTGTCCGGGTCGTGCGGGTCCTTCCAGGGGTAGGTCACGTCTTTCCAGTGGTCCACGTACTGGCCAAGGGCCGTGTTCAGGTAGTGCCGGACCTCTCGCTCCCACCGGGTCCCCTTGGCCTTCGCCGCGTTGCTCACCGGCGGCTCCGTCGAACAGCCGCCAGACCGACACCCAAGGTCAGCAGGAACCAGACGGCGCGACCGGCGATGGCCATTGCCAGGGCGATGACCGCCAGGACCAGGAGCACGTCAGACACCGGCTGGCACCTCCGCCGGGACTGTCACGGCGACGTGTTCGGCCGCCACCGTCTCCACGCGGAACGTGGCGCGCTTGACCCAGCCGCTCTCGTTGCCGGTCGGCTTCACCTTCAGCATGGGCAGAACGCGGCCCTTGTAGTTCTCGGTGTAGGTCCGTAGGACGACGGCCTCCACCATGCGCACACTGTTGCCGCGTCGTGCCGCGTACACCAGGGTGTCCCCCTCGCGGATTTCCTGGCCGGTGAAGTCATGGATATGGCCCCTCTTGGCCACCGTGCTCTCCTTTGGTTCATGTCCGGTCGGCCGCGCGCGGCATCGGGCGCACAGTCGGCCGAAGTTCGTTGGTCTGAAGGGTGTGATCAGAACGGTGCGGAATCCGCGGTGACCTTGGACAGGGAGGGAACGGCCGGGCCAGCCTCCGTCGAGGCGGGGCCGTGCACGGTCAGGACCGGCTTTCGGTACGCCACGTCCACACCGGCCTTGGTGGTGAACTCGACCAGCTCCAGGCCGAGCGAACACAGGGCCGGACCGCCGACGACCTCCAGCTCCCGCCAGAGCGTTTCGAGGCTCTTCATGAAGTCCCAGGAGCCGGTCATGAGCCGGAAGCGGCCGAGCTCCGGAGCGTCGGCCAGGCGGAAGTCCATCCGCTGGTCTGGCTTCGGCCCGTGACCGGCCTTGGCTGCGGCCTTGCGCTCCTGGAGCGTCGTGGGGCAGCCGCACGGCTGGCCGTAGCGCGGGTCCTCCGGGTCGGTGAACTCCACGCCGTCGCAGGCATGGATCGGCTTGCCGGTCATGCCGTACAGCGCCATCCGGAACGTCACAGCGTCCGGGCCGTCCACAATGACCTTGACGGTGTCCGTGTCGGTCAGCACCTCCACGCAGTCTTCCTTGGAGGTCTCCCATGGTTCGGGAGTCCCGCCGTACAGTGCAGCCACGGTCTTGCTCACCTCCGGGTCACCGGTCGTGATGCGCCACGCCTTCAGTGCGACGGGGCGGCCGTTGAGCTGCTGCCCGGCACGGAATCGGCCCACGTAGTCCGAAGTGAAGACCTTCGGGCGGGCGTTGGGGTCGGTGTCGAACACGCGGAGGGTGCGGGCCACTGTGCTGGCTCTCCTTGGGAGTGCTGGGAATGAGACAGCGCAAAGGCCCGGCGCGCGGGCCGGGCCTCTCGCTACTTCCATGCACTGGGGTCCGTGACACCCACGGTCGGCCTACGCCGCGCGCCGCTGGGTGCCCGTCTCCGCCTCCCCGCCGGAAGCCACCGGCCGGCCGATCACCCCGCGCTTGCCCTCCCGCTCCCAGTCGAACACCGCCCGCAGATGAAGGAAGGTGGCGAACAGCTCCGGCGTGTGCCGCACGGGCACCAACTTCCAGCCCTCCGGCCGGACGTGGAGAACGGCCGCCGCGTCGATCTCCGGCAAGGGGACGGACTCCCCGGTGTCCGCCTTCACGATGCGGTCCGCGTTCGCGTACGCGGAAAGCTGCAACGCCACCTCCTCATGAACCCCGGACCGGGTCGTCTTCCAGTCCAAGACCACCGTCTCCCCACCTATCCGCGCGATGGCGTCGAAACTGCCGGCGTAGGTGTGCTGGTCCGACCAGACCGCGTCCTCCAGGAACAGGAACTCCGGCTGCACGGCGTCCAGAAACTCCCGAAAGTGCTCCGCGTAGGGGCGGAGGTCCGGGTGGACGCGGGTCACTGCCTCACCACGGGCCAGGCGCTCGAACACATCATGCGCCGCGCTGCCAATGTCGGCCGCCGCCTTCGTCACCCGCCGGGGCGCGCCCTTCAAGTAGTCGATGGCGCCGGCCCGGTCGTTCATCGCCAGGCCCACCAGGGAGCCGAGGTTGTCCACGGCCGCCGTCGCCACCTCCTTGGCCGCCCAGAACGGCAAGAAGCCCTTTGGGAGCATGGACAGGACGCTGGTCACGCCGGGCGCCTTGGCGCCGGTCTCCGGGTCCACGTAGAACCGCGATCCGGACCGGCTGATGGTGTTGATTGCTGCCACAGGAATCTCCGCTTGCTCACCGGCCCGCAACGGCCGTGCTCAGTCGCTTATGGCGCAATCCACTGGGGGGCGTGACCAGCACCAGCACTCCAGATACGGCGAAGGGCTCGAACGGAACGCTGTCCGTTCGAGCCCCACTTTCACCGGCCGGTGCCGTCGCCCACCGACTCCTCCGGCACAGGAGCCGGGTTGTACTTCGCCGCCACCTTCCGCGACGCGCCCTCACCCAGGACCAGGATCACCAGGAACGTGATCGCGTCCATGGCCTGGTCATTGACGGCCACGTCAGCCACAGCGGGAACGTAGTGGCCCAGCAGGACCAGGAGCGCGCCCAGGGCCGTGCGAACCCGGACGGGGTTGTCACGGATGGCCTGGCGGATCAGATCGAACATTCAGTCTCCCAACTTGTTGAACAATGCGCGGACGCTGTCGCGGAGTTCGGACAGCGTCCCGGTGTTGTGGAGCACGTGGTCCGGCGTGATGCCGTCCAGCTCCAGTTCTGAGGGGTGCGTTCCGGCGTCACCGTCCAGGCCGGCGCCCGGCCGCTCCACCCGGACGACCACGGCGCCCTCCGCGCGGAGCGCGTCCAGCTCATTGGCGTAGCGGGCATCCGCCACGACGCACGGCATGTGCCACTCGCTGCCGTGGCGGACCTGGGCCAGGACCGGCCGGACCCAGAAATCCGGATCGCGGTCGCGCACTGCCTGGCCGCACTGCTGAAGGAGCCGCCGGACCTCCCCCAGGGCCTTGGCGCCCTCCCACCCGCCGTGGTCCTCCAGAGCGTCCTTCAGCCGGTGCTCCTTGTAGCAACAGCACGAGACAACCAGCGGGTTCAGGCGAACAAGGGCCGCTTTCAGTTCGTCGGCGAACGCCAGCCGGGTGAAACTGGCGTGGCGGACCAGGAGCTGGGCCACGGTGTCCTTTCCAGACCGGGCCTTGCCGACGAGAGCGATGTGCGGATGGGGCATGAGTCCTCCAGGACAAGGGGCGGGTGCGCGCCCGGATGCACTGGGGGGCGTTACGCCCCGGCCGCCTTGACCAGGGCCGCGATCAGCGTGCCCAGGGAGGTGACTGCTGCCAGGGGCAGGGCGTAACGCCACCGCTCCAGGCCCCGCAGCCGGCTCTCATGGTCCGCGAGGGTCTGGGTGACCGCTTCGTGGGTCTGGGTCAGGCTCCGCACGTCGCCGCGCAGCGCCACCAGCTCGTCGTAGATCTCACGGGCTCCGATCATCACGGCGCCCAGCTCGTCGCGGTCGCTCACCTCTACCCCTTCACGGTGAACCCGTGCTTCGCGCCCAGCAGGCGCAGCGAGGCAATACCGGGGATGCCGTCCGGGGGGCCGCCGACGCGGGCCCGCTTCTGCCAGTTCGCGTACGCGATGCGGGTCATGGACCCGAACGAGCCGTCGCACCAGCGGGCGTCCAACAGGCCCTCCGCCTTCAGTGCCGACTCCACGTGCCGTACATCGGCCGGGTAGGTGGTGCCGCCCTGGCCCCGGTCCGGGTCACGGACGGCCGCCGCGCGGATGCGGACCAGGGACACCCCCGGCGTGACCTTGGTCGGAGGCTTGGCGCCCTTCTCCGGCACGGTGATCTGGTCGCCGGGGTGGATCACGTCCGGATTCTTCACCTGCGGGTTGACCGCCAGGAGCGCGGCCAGGGAGACACCAGCGGATGCGGCGATCGCGCCCAGGGTCTGGCCGGCCTTCACCACCACCGCCTTGCCCTTCGACGATCCGGCGTGCGAGCCGGACGTAGCCGGCCCGGAGGCCACCGCCTTGTAGACGAACCCGGCCTTCCCCTTCAGGGCTGGGTCCGCGGTGGTCACGCCCTCCGCATACTGCGGCAGGCCGTACCCGTGGACGTAGGCGTCCCGGCGGTTGCGGCGCTTGAGGTAGACGCCGTCCCCCTCCGCGCTGCCGCTCGTGTTCGTGTTGCCCTCAACGGTGGTGATCGTGTTCGCGTCGTACGCCACCACGATGCCGGTGTGCGAGTTTGCCGACCGGCCGTAGATCACCTGGGCGCCGATGGCGGGGTACGCGGAGTACCGGCCCCGGGACTTGAACCAGTTGTACGCGGTCCACACCGACGCGGTCACCGGGAACAGCGACGCCGCGCCGGCCTCCCGGGCGCTCCAGGAGACGAACGTGGCGCACCACGCCTGGTTCTGGCTCCACTCCAGGCCCGGCACGGCCGGGCTGTAGCGCTGGTGGTTGTTCCAGTGGCCTCCGCTGTATCCCTCGCGGTAGCCGATCTCTCCGCGTGCTGTGCGGATTACGTCTGCGGCCTTCGCCAAGCCGCCTCCTTCTGTCGTGCGTGGAAGGCCCCGCCGGTAGTGCCCGGCGGGCCGTGTGGTCGTGGGTGGGTCAGGACGCGACGCCGTACAGCCGTTGAACGCATGCCCATACCGTCGAGTTGGCCTTGGCGCGGGCTTGGAGCTTGATTTCCGGATGCGCGCCGAAGGTGTAATTGGGGATCTTGAACGTTGCCTGGACGGCCTTGTTGGTGGAGCCGGAGGCCACGGTCTGACCGTCCACGGTGATGCGGATATCTCCACCGGCCCCGTTGGCCAGGGCCTGGGCGAAGACCTCCATGCGGGGGTGTTGGACCTCGGGCCAGGCCACTTGGAGGTCCGTCCAGTCGGTGGCCTTGGTGGAGGGCCAGTCAGCCCCCTGGGCCGGGGTCATCACGACGGGCAGGTGTGGGCGGGCCAGGCCGCCGGCCACCACGTCCTCCGAGAGGAGTTCGTTGCCCTGGGCGTCCTTGATGCGCAGGGCCTGGGCCTGGCCTTCGGCCGTGGTGCCGTTCCACACCGACAGCGCTTCGCTGCCGTCTCGACGGCGGACGACCAAGGCGTGTTCGCCCGCGACAGGGCCCACCTCGCCGACCCGGAACGTCTCCCTGCCGCCGGGCTGCCGAACGGAGAGGCTGCCGCCTTCCCCGATCTTCACGTCTCCGTGAAGTACCTGATTCATGGCCGGCCGCCGGTTCGCGGCCGTGGTCAGCATCCGCAGCTCCGCCTCCAGGCGCCGGATGCGGTCGGTCAGATCCTGCGGGATGATCGCCACTAGGTCGCCTCCAAGAACAGCTCTGCGGCCTCCTGTTGGCCGCGTTGGTCTGGGGTAACGCTCAGCCCGACGACCCGGAACGTGGCGTCCAGGCCATCGGAGAACCAGGTGTCGCGGATGCGAAGCCGGACGGTTGCGCCGATGAGCGCGGGCGTCACTTCTCCGTCCAGACGAACCTGAATCGACGGGATCACCACCGGCTCCTTGGCACGGGCCAGGTCGGCCTTGGCGTGCTCGTCCAACGTGGTCAGCCGCTCCACGGTGGTGTAGTCGCTGTGCCCGTCCAGGCGGGGCCACCCCTCCGTCAGCTTCTCGGGGTAGGACCACTCCGTGGACAGCAGGGGGTTCGACTGTTCGGCCTGGTTCTGGTTGTCGGTCGCGCCCCGGCTCTGCCAGGTGTTGGCCATGCCGGTGGCGTCCTGCGGCCAGGAGTAGGCCAGGACGTTGCCCGGGTACGTCAGCATCACCGGCACCGCGCCAGAGCGGATCTTCGGGTATCCGAGCTGGAGTCGCTTCACGCGCTCGCCGGTCTCCGCCTCCCGGTAGACCTGGACGCGCCACTCAAAGCCACCGTCGACGGCCGCCAGCCGATCCAGGGCCTCCCGTACCGGCGTCGCGTCGTACCGGGAGTACGTCCGGTCCCGCCGGACACCGGCCGTGCCTGTGTAGTCGATGCGGATGCCGATGTCTCCGCCGGCCTTGGTCGCGGCGTAGGTGGCCAGGTTCCGGGCGATGTCGAGCTGGTCCGCCTGCTGTGCCTCCAGGGTGTCCCGGATTTCGCGGTGGTCCCAGTAGGAGTCGAACGTGGCCGCCTGGAGGGCGACGGTCACCGCGCCCCGGTCGTTCGTGGCCGGCGTGGCGGTCCAGATGATGCCGCCCCACCACAGGTCTCGGCCGCGCTCCACCCACAGTGCGGTCCGGCCCGGCGTCACGGCGGCCTTGATCCGTGCGGCCGTCGCCTCATCGGGCGCCGCGAGGGTTCCCCGCAGGGTCCCGGCCTTGCCGATGTAGTCGTCGAAGGTGACCTGTTGGACGGGGAGCACGTCCAGGAGCTGGTCGGTGCGCAGGTCTGTGAACAGGAACCGGTAGCCGGCCGGGGGTAGGGCGGCGGTTGTCATGCTGGGCCTTCCCACCGCAGCGTGGCGTAGCTGTACCGCCCGGGGACGTTGTCCAGGGCAGTCGCTGAGTAGACGTTCACCTCGATGAAGTCGCCGGCCTGGAGCACGAGGGGGAGGGCGGTGGCGTGGCCTTGCCCACCGTTGGACCGGGCGACGAACGACATGTGCCATTCCCCGACGCCGGCGTTCTTGGTGACGGTGACGCGTGCCTGTTCGGCACCACCGGGCCATGTCTGCTGGGCGTACACGGTGTAGAGCCCCCCGACGGGGGCCACGAGGCGCGTGGGGTTCGTCGGCGTCCACATCGATGCGTCGGTACGCGCATCGACGCTGCTCCAGCGAACGGGGGTGTAGCGGTTCGCCGCCAGGTTGTAGGCGTCGGTCTTGCGGACGGCGACGTAGTGGCGCTCCGCCACACTGCGCCAGCTCTCGCCGTCCCAGCGTTCCAGGCCACGGTTGTTGTCGCGGTACTGGCCGGGGTAGGCGCCGCCGTAGTTCAGGCTCCAGCCACCGGCCTGGATGCCGCCCAGGGACACGGTGGTCCGGCGACGGTCGGAGACGGCGGTGGCCCAGTCGATCCCGCCTGTGCCGGCTGAAGTGCCGGCGGGCACCGTGATCTCGTACAGCTTCTCTGCCGTGCCGGAGGCCGCGGGAGCCTCCGGCGTGGCGGACGGGGTGCCCCGCGCGACGACCAGGGCGGCCGTGGACTGGTCCGACCCGTCGTAGGCGGAGTCGTCGACCCGCAGGAGGACGCTGTCCTTCCGCGGATACTGCGCGTCTCCGTCCGCGATCGTCAGCGTCTCCGGCTCCGTGACCGCCACCGGATACGCCCCCTGTACGGAACTGCCGCTGATCAGGGCCCGGCCGGTGCCGATCGTGCATTGCATCGCGCCGGCCGCAGTCAACGCGAACGGGTTCCCGCCGGGGACCACGCCGCCGCGCGAGGTGAGTTCGCCCTGCGGCGTCCAGGTGCCGACGGGGACCAGCCGGGTGTCCGCCCGGGTCTGCCCGCCACCCGGGGAGTCCCGGTTGACCAGCCAGCCACTACGTACAGTCAATGTTGCCTCTCACCAGAAAGCCGACCGCCACCGCACGGTGACGGACGCCAAGGGGTCGTAGAAACCGGGCGCCGCCCGGAAGGCCAGGACGGAAACCCCGGGGTCGAACGTGAACGTCTGCTCCGGCACGCTGGACGCGGTCACGGTGTAGAGCCGTGACGCGGTGTCGTTGAGGACGGCGGTCCCCTCGGCGCAGTCGATACGCAGGACGTCGGACTCCGTGAGGGTGATGTCGTACTCCAGGCGCCAACCGGTGTGGAGCTGGAGCAGCGAGGGACGTACCACCGGGCCCCGGAACTCCACCACCGGATGCGTCGGGGCCTCGCCGAGGTTGGGCGCCACGAGAGTGCCGGTGGACCCGGTGATGCCCCACTCCAGGGGGTAGTCCAGGCCGTCCGTCCAGTCCAGGCCGGGTTCCGGGGCCGGTAGCCCGCAGGTCACGCGGTTCTCCTGCGGTTCGTACCGGCGGGGGTCGGAGCACTCCCACACCACCGACCCGTACGGCTCCCCTCGGGTGTATCGACGGTCCGCAGGCAGGGCCCGCCGGGTCACCCGCCCCCGCATCAGCCGCCGGGCTCCGGCGAGTTGAACCACCAGGTCCTGTTCCCGCTGGGTCGGAGCGGTCGCCCGGCGCAGATCCGCCAAGAGCGCGGGGTAACGCTCCATGCTGTCCGGCAGAACCATGAAGTCGAACTGAAGGGTGCGGGTGCCGGCCAGGAGCTGGCCGGGCCAGCCCCCGTGTTGGGTGGGGCGGAGCACGGTGGTCGACTCCACGTCGGGGAGGTCGTCCCATCCGGTCAGTTGCTCGCCCACGTACTCCGTGGTCTCGCCCATGAGCAGACCCGCGAACTCGATCTGCCCGTCTTGGGTGACCTGGTCACCCGATGCGTCCAGTAGTTGTGGCACGTCACCCCCTGGCCTTCATGAGCCAATCCAGTTCACGCGCGACCTGGGCAGGCTGCATGTCGCCAGCGTGAAAGTTCTCGATCGTGATTGCGGTCGAGGCGCGGCCGCTCGTCGGACCGGGCCGGACCTGTTCGGCCCGGGGCAGTACCGGCCGGGTCCCGACCATGGCCGGGATGTCCGCGGTAATGCCGCCCAACTGCCTTTTGAGTTCGGGGACCTGGTCCTGGATGCCCTTCATGAAGCCCGTCAGCAGGAGGCGGCCGTTCGGGGTCAGGATCCGGGCGTCCAACGCGGCCGGGCCCTTCCAGTCCGGCAGCATGGACGTGATGCTCCCCAGCTTGTTCTTCAGGCTGGTGATCATGGACGAGATGCCGTCGATGAAGCCGCGGATCAGCGAAGCGCCGGCGTTCCAGAGAGTGGAGCCCAGGTTGCCCAGGGCGTCCCGGGCCCGGCCGGGAAGGCTGCGGAGGGTCGCCACGGCGGACGAGATTCCGGAGGAGATCCGGTCACCCATGGACGACAGGCCGGAGCGGGCCGCCGAGACGATGTTGGAGCCCATGGTCTTGACCTGCGCCCACGCCCGTGACGCCAGGTCCGCGAAGTAGCCGACCACGGCGGAAACTCCGGACAGGACGACGGAGCCGATCTTGGTGAAGATGCTCCCGAAGAACGAAGCCAGCCCCGACAGTGCCGACTTGGCCGCGTCCAGCGCTCCGGAAAAGTCGCCACGCAGCAACGCCACAATGGCATTGATCGCCGGAACCACGATGGTGGTGATGTACTTCGACGCCAGTTCGGCCAGGACACCGGCCACCTTGCCCACCAGCGTGATCACCGGAGTAATGACCGGAACGAGGGCCTTCAGAGCACCGGCCAGCAACGTGCCCAGGGCGGTGATCAGCGGGCCGCAGGCGACCAGGAGTTCGCCCAGTGCCTTTCCGATCGTCGCCAGGGCAGGCGCCAGGGCGCTGATCAGCTGGCCCACCAGGTCACCCAGGATCGGCGCCAGCTCTCCGATCACCGAAAGGATCGGGCCCAGGATGCTCGGAAGCTGGGCCAGGATCGGCTTCAAGGCCGTCAGCAGCGCCCCAGCGATCTTCGCCACCAGGCCGCCGACGATCTCCAACACCGGCCCCAAGGCCCCGGCCAGTTGGCTGATGAGCTGGGCCGCGATCGGCAGGATCGCGGCCAGGGCCTGGGCGACCACCTTGACCACCGGGGCCAGGCCGGCCCCCAGGCTCTGGGCCAGTTGAACGAAGACCGGGGCCAGGGTCCCGGCCGCGCTCTGCACCGGCCCGGCCAGAGTCGTGACCAGCGTGTTCAACAGCGGCATGACCGCCTTCAACGCACCACCCAAGATCGTGGAGACGGCCTTGCCGACCGCCGAAACGGTCTCGAACAGGGCCCGGAACGTCTCCTGGGCCTCCGGAGTCGCGGTGACCTTGGCGGCCGTGGCCGCAAGCTCCGAGAGAACCTGAAGGGCCCCGCCGCCGGCGTCGGCCGCCGCGCCCAGGACGTTGCCCAGGGTCCGGCCGATGTTGGCCAGAGTGCTACCGAACTCCTTCGCCACGCCTACGGCCGCCTCGATGCCGCGTTGCATGGCGCCGGACTCAAACGACCGGTCCATCTTGGCCCGGAGGCGGTCCAGGCCCTGGCCCATGGAGGTCGTCATCCGCTCCCAGGTCGGAGCCGCCGCCGCGCCGAGCTGGACCAGGCCCTGAAGGACCGTTCCGGGAAGGCTCTTCATGTTCTGAAGGCCCCGGGTAGCCCCGCTGAGGGCCTGGCCCAGTGCGCCGTCCTGGGCCAGCGTGCGGGCCGTGGCCAGGGTGTCCTTGCCCATGGCGTTCAGTGCGGAGGCGGTGCCGGAAAGCTCCGTCCGCAGCACGGGCAGGACCGCGTTCGCGGTCCGGGTGAGGGTGTCGCCCAGGCCCTGGAACAGGGAGCCTTGGACGGACCGCTTCACCTCGTCCCACGCCGGCCCCAGGGCCTTGGCCTGCGTGACGAAGTCCTGCGCAGCGGGCGCTAGTTCGGCCATGGCCTCCGCGTCGCCGGCCAAAGCGTCGCCCAGGCCGGACATGCCGACCTTCAGGGCCACGCCCGCCGATGCCAGGGCCAGGACGGCCGGCGCGGCGACCCCGGCCGCTGGAGCCATGGACGCGATGGAGGACGACAGTCCCGCCACCGCCGGAATGCTGGAGGCGGCCGTGGACAGCTTCCCCAGCGTCCCCACCAGGGACAGCACCTTGCGGCCGGCACCGCCGGAGCTGTCCCCGACGTGGGACACGTCCCGGGCCAGCGTGGCCAGCCGGTCCCGGTCCGCTTCGACGCGGGCGGGAATCGTCATCGGCGGCCGGATGCGCGCCAGCTCACGACGCAGCCTGGCGACTTCCCGTTCGGAGACCTCCAGGCGGACGCCAAGGCCGGCGTTCGCGCCCTGGAGGCGTTCACGCAGTCGTGAACGGAACTCCGAAAGGTCCGGGTCGACGTTCACGCGGACACGGGCGCGGACCCGCGCCAACTTGGCGTTCAGCCGCTCTCGGAACCCTTCCAGGTCCGGGACGGCCTGGACCTGGACGCGGGCCCGCCGCTCGACGCGGTCAAGGTAGCGCTGGAGGCTGACGGCGAAGTTCGACGTGTCGGGAAGGACACGGATCGAAAGGCGCCCTACCTCGCGGCCTCCGGGGCCGGCCATGAATTACCCCCTGGTGCAATGGGCTTGGCCAAGGGGTGCGTGGACAGGTCGAGGCGTGGCCGCTCGTGCTTGTCCGCCTTGACCTGTGGAACGTTGACGGGAACCGGGTCCCGTTTGAGGCGTCCGCCGGAGACGCGGACGTTGTTGGCGTCGGCGAAGCGCACGGCGTCCAACAGGGCAGCCAACAGGTGCGTTTGCACTGTCCAGCCGCGATGTTCGGGCCCGCCGGCCAGCGATGCGGCCAGGGCGGAGCCCGGGGGCAGGTGCTCGGACAGGTGCCAGGCCCGGCGCGGCGTCAGGGCGCCCCGCCACACGTCGACCAGGTCCAGGCCGTAGTAGCGCTGGAGGTCCGCTCGGAGCGCCGCGCCGTGGCCCTGGGCTATCAGCTGTCCGAGCGCGGAGCTTCCCCCACCTGGGTCTCCTCCTGCCACTCACCGACGGTGCGGACGAACACGGCCAGCGGCCAGTCCTGCATCTCCGTCTTCAGCGCGGCAGGGTCGTCGGCCACCAGGAGGAGCAGGTCACGGATCTTGGGGACCAGCTCCTCCAGCTCCTCCGATCCGGTCTCACCGAAGCGCGCGAGGATGGCGCGGGCCGCCTTCAGGCCGTCGTCGGGAAGCATGAGGATGTTGCGGAGCTGGATCGTTTCGCCGGCCCGTGTCTCCAGCGGAAGAGCCTCGTACTCCGCCGCAGCTTCCGCCATCATGTCCGCGCAAGAAAGTGCCAAGGGTCGTCCCCACAGTCGGTGTTGGTGGTCCCTGGGAAGAGGTCTTCCGCCTGGAGGGACGGGCCAGGCGGAGGGGGTTCGCGGGGCGCTAGGCCGGCGCCGCGCTACGTCACTCCTTGTCGTGGTGCGGCGGAGGCTCCGGAGCTGCAACCTGGGCCCATTCACCGATGGCGCCGCCCAGCTTCGACGACCCCAGGAAGGTTCCCTTGATCGGGAACGACACGAAGTCGTCCGACGACATGCCCACCGCGTCGGAGCCCAACAGGGAGACGCGCGGGTGGTACAGCGGCAGGTAGTTGGTGCCGTCCACCAGGACCACCAGGAGCGCCTTGGTCTGCGGGGTGGGCGTGGCCGGGATGCGGAACGACTTGTCCGCCTGGATGGCCGCCGGGCCCGCACCGAAGTAGAGCTGATAGGTCAGGGCCGTGGCCTGGATGGACTGGAAGGTGACGGAGTACGTCACGTCCGGGGTCGTCGCGCGGAGTTTGGCGTTCTGCCAACTGCCCTTGATCTCCGGGTCGTCACCGTCCCGGCCGAACTCCGGCAGGGCGTCAAGCTTGGTGTGCCCGATGCTCTCCCACGCGCCGCCCGGCTTGGTCGGGTCGGCCAGGTCGGCGGGCTTCTCGGTATCGGGGTCAGCGATGAAGATGTAGCCGCCGGCCGGGACGATGGCGGCGTTGTCGATCAGAGCCAAACTGTTCTCCAGGGGTAGGTCATAGGGGCCGCGCGGTCACGCGGTAGGCGGCTTGGAACCGGAACAGGTCCGGCCCGGCTGGCGGGTCGCCCACGCGGATCTCCGCCGGCCCCGACACGTCCTCGAACCGGCTCAGGTAGCCGTCGGCACCGCGGAATTGCGCTCTGCACGCCTCCGCCAGGGCGACCCGGACCGTGCGGGCCAGCCGGGAAGCGTCGCGCCGGTCGACGGCGGCGCACTGCACGTCGATCAGGGCCACGTCGATGCCCTGCGGGGTGGCCGTGCCGCCCGGCACGCGGCGGGCCACCACCAGAGGTAGCCAGTCGGCCCAGTCGGCGGGCCAGCCCACGCGCACCGTGGCACCGCTCAGGACCTGGCGGAGGGCGTCGGTCACCAGGGCATCCACGTCGGGTAGTACCGGCCTCATAGGCCCGCCTCGATGGCGTGGATACCGGGCACCCAGCGGCCGTTCGGCGTGAGGTGGCCGTAGTTGATTGCGTACACGGCCGGGTCCTCCAGGGTCACCGTGGAGTCCGTCCGGTTCGTGCGGACCCGGGTGTGGGCCGCCAAGGCCCCGGTGTGCCGGTGCGCCTCGACCACGGCTCGGACCCGGTCGGCCCGCTGGTCCAGTTCGTCCGCGACCGCGTCCCGGACGCCCCGCAGGTGCGCCACGATGCTGTCCGTGTTGGGCTTCACCGTCGCCATGGGCTCACCCTCGTTTCCGTATCGTCGCCACGTCGTGGGCCAGGCGCAGGGAGCCGCCAAAGCGCTGGGGTTCCCCGACCACGGTCCAGACCTGTCCGGCCCACTCGACGCGGGACCAGGGCCCGGCCGGCAGCGACCGGGCGTACACCCGGTACTCCGTGCCGGTCAGGTAGCCGGCCTCGCCGCTCTCGTCGGTGGTCGTCGGAAGGACGCGGGCCCGGATCGTCACCGGGGCGCCGGGGCCGGGCTTGGTGCCGCCGTACCCGTCGTCCACGTCCGCCGTCGGGTAGACCGTGACCTGGTCGGGGCCGGAGTCCAGCAGGCTCACAGCGCACCCCCCAGGGACTCCACGGGCACGGCGAAGAGGCCGGAGGCGCCAACGGCCGCGCGGATCATGCGGGCCTCGCCATCGGTCAGGCCGCCCCCGGTCGGGAGCGAAGCGGGAAGCTGGTACTGGTATCCGCCGACTACCTCTGACCGGTACCCCTCCGGGTTACGGACCCGCACGCGGATCTCCGCCGGCCCCGACACGTCCTCGAACCGGCTCAGGTAGCCGTCGGCACCGCGGAATTGCGCTCTGCACGCCTCCGCCAGGGCGACCCGGACCGTGCGGGCCAGCCGGGAAGCGTCGCGCCGGTCGACGGCGGCGCACTGCACGTCGATCAGGGCCACGTCGATGCCCTGCGGGGTGGCCGTGCCGCCCGGCACGCGGCGGGCCACCACCAGAGGTAGCCAGTCGGCCCAGTCGGCGGGCCAGCCCACGCGCACCGTGGCACCGCTCAGGACCTGGCGGAGGGCGTCGGTCACCAGGGCATCCACGTCGGGTAGTACCGGCCTCATAGGCCCGCCTCGATGGCGTGGATACCGGGCACCCAGCGGCCGTTCGGCGTGAGGTGGCCGTAGTTGATTGCGTACACGGCCGGGTCCTCCAGGGTCACCGTGGAGTCCGTCCGGTTCGTGCGGACCCGGGTGTGGGCCGCCAAGGCCCCGGTGTGCCGGTGCGCCTCGACCACGGCTCGGACCCGGTCGGCCCGCTGGTCCAGTTCGTCCGCGACCGCGTCCCGGACGCCCCGCAGGTGCGCCACGATGCTGTCCGTGTTGGGCTTCACCGTCGCCATGGGCTCACCCTCGTTTCCGTATCGTCGCCACGTCGTGGGCCAGGCGCAGGGAGCCGCCAAAGCGCTGGGGTTCCCCGACCACGGTCCAGACCTGTCCGGCCCACTCGACGCGGGACCAGGGCCCGGCCGGCAGCGACCGGGCGTACACCCGGTACTCCGTGCCGGTCAGGTAGCCGGCCTCGCCGCTCTCGTCGGTGGTCGTCGGAAGGACGCGGGCCCGGATCGTCACCGGGGCGCCGGGGCCGGGCTTGGTGCCGCCGTACCCGTCGTCCACGTCCGCCGTCGGGTAGACCGTGACCTGGTCGGGGCCGGAGTCCAGCAGGCTCACAGCGCACCCCCCAGGGACTCCACGGGCACGGCGAAGAGGCCGGAGGCGCCAACGGCCGCGCGGATCATGCGGGCCTCGCCATCGGTCAGGCCGCCCCCGGTCGGGAGCGAAGCGGGAAGCTGGTACTGGTATCCGCCGACTACCTCTGACCGGTACCCCTCCGGGTTACGGACCCGCCGCTCCGCAGCCGCCAGGGTGATGGCCACCGCGACGGCCGGGGCCCGGCCCGGATCAGGCCAGGCATCCCCGTACGCCCGCACGAGGGCGGAGGCGTCCGCTAGAGCCGCCTCCGCCTGCGCTCGCTCCTCCCCGACCAGCTCACGGCCCAGCCGCTGTTCCAAGGCCGCCATGTCTGCCAGGGGCTTCACGCGGCCTACTTGTCGGCCGGGGGCTTGGACGCGGTGGGCATGTCCAGCTTCACGGCGCGCACCAGGCGCTTGGTGGGGTTCTTGCCTCCGCCCACCGGGTCCGTCATGACGTTGAATCCGGCGAAGAGGTTCACGATGGAGCGGTCGCGCAGTTTGGCCGCGTCGTAGTCGCGCACCCAGCGCATGGCCAGGCCGTTGTAGGACTGGCTGGAGCCGCTGGTCACGCCCGCCGGAATGGCCGGCGCGCGGGTGGCCAGGACGAACGCGGACGGGACGAACGCATACGCGGAGCGCGGGTTGATCGCGTTGGAGGTCACGAGGTTGAAGCCGGCCAGGTTGCCGACCATGGCCTGTCGGAGGGCAGAGTCCGAGCCGGACTTGGACACGTCGTTCAGGCGCCCGGACTTCAGCAGCGCGGTTTCCACGTCGGCACCGATCAGAAGCGTCCGGTCGTTGGTCGGCACCTCGTTCTTGTTCAGGGCCGCGCGGGCGTCGATGAAGGCCGGGAACGGGTCCTTCTCATCGACGACGATCGCCGGGACGCTGTACGTCGCGGTCTCGATCATGTTGGCCACACCCGCGTCAATGGCCTTGGCCACGGCGTTGACCTGAGGCTGGAGCACCTGGGAACCGAAATCCCGGATATCCAGGGTCAGTTCCTCGTCCGTGACCGCCACGGCTGAGTAGATGTCCTTGTTGAGCTGGACGGTGAGGGAGTCCTCCGCCAGCTCGTCCAGGACGATGTCCGACGACCGGTCGTTTCGCCAGTCGTACTCACGGGCGTTGAGCTGGGCCGGAATCCGGACCGTGACCGAGTCGGCCTTGGCGCCGGTGAAATCAAACCCGGCGTTCGACCAGACCAGGTTGGCCAGGACCAGTTCCCGTTCCAGCAGTCCGAGGGACGTCGCTGCGATGGTCTCCGACTTCAGAAATGCGTTTGCCATGTGCTCCGCTCAGCTGGGCCCCGAGCCAGCACGCAGCACACCCAGGGCCTTGGACATGAACCCTTGGTTTTGGTGCTGCGGTGAAATGCCTACCGGCGGGCACGCGGGATGCTGGCCGCCAGCTCTCCCGGATCGCTGGGAGCCGACGTGACCGACGGATCAAGACCGCCCCGGCCCATGCCGCCGGCCTTGCTGTGGAACAGCTCCGCCAAGGTCTTGGCGTCGGCCTCGCGGGCGTCCTCGTCGGCCCCGGCGATCCGGACGGCCAAGGCGTCCGGCAGGCGGTAGCGGCGGGCCAGGCGCTCCCGGTGCAGCTCCGTCTCCAACTCCGTGGCCCGCTCCGCCACCGCCTGGAACTCCTCCGGCGACCGGGCCGCCTTCAGCGCCTCCGCCGTCTCCCGCGCCTTGGTGCGGTACCGGGCCGCCTCCGCCCGTACGGCCTTCAGCTCCACGCGCAGCGCGTCGGTGTCCAGTTCCTGGCCGTCGCCCTGTTCCTCCGGCCGGGCCGGTTCCTCGGGGCCGTTCGCGGCCTCGGTCCGAGCCTGCCCGTCGTCGGCAGGCTCGGAGGTGGTGGGTGTGGTCTCCATGCGGAGCCTCTCCTCAGTTTCGTGATGATTCGATGTGGCGACGCCAGGCCCGCCGGGCTTCCGCGCCGGTCATTCCGCGGGTGACCTCTTGCCATTGGCGGTCGTAGTCGCGGGCCTGCGGGGTCATGAAGTCGTTGCGGGAGTAGATGGGGACCGTCTGGCAGTGGCACCCGTTGTGGTAGCGGGTCAGGTCCTCCAGGGCGACCGGAGGCCGTCGGTTCGCGCGGACCCGACCGTCGGGGGCGCCCTTGGGCTTGCGCCGGCCGCCACCGGCCGCCGTGGACTGGGACGTGTACATGGCGCCCCGGCTGGCGAGCATGGCGCAGAACGCGCACGGGGTGCCGTCGGTCACCCGGGCCCAGCCGACCACCCGCCGGTCCTGCTTCGACGCCTGGTCGATCAGGTCCCGTCCGCCCCGCAAAACCTCGCGGTCGGCTGCTCCGGCGGAAGACCGGCCGGCGGTGTCCACCGCGTCCTCCAGCTCCTGAAGGAACCAGCGTCCGGTCGTTGGTCGGCACCTCGTTCTTGTTCAGGGCCGCGCGGGCGTCGATGAAGGCCGGGAACGGGTCCTTCTCATCGACGACGATCGCCGGGACGCTGTACGTCGCGGTCTCGATCATGTTGGCCACACCCGCGTCAATGGCCTTGGCCACGGCGTTGACCTGAGGCTGGAGCACCTGGGAACCGAAATCCCGGATATCCAGGGTCAGTTCCTCGTCCGTGACCGCCACGGCTGAGTAGATGTCCTTGTTGAGCTGGACGGTGAGGGAGTCCTCCGCCAGCTCGTCCAGGACGATGTCCGACGACCGGTCGTTTCGCCAGTCGTACTCACGGGCGTTGAGCTGGGCCGGAATCCGGACCGTGACCGAGTCGGCCTTGGCGCCGGTGAAATCAAACCCGGCGTTCGACCAGACCAGGTTGGCCAGGACCAGTTCCCGTTCCAGCAGTCCGAGGGACGTCGCTGCGATGGTCTCCGACTTCAGAAATGCGTTTGCCATGTGCTCCGCTCAGCTGGGCCCCGAGCCAGCACGCAGCACACCCAGGGCCTTGGACATGAACCCTTGGTTTTGGTGCTGCGGTGAAATGCCTACCGGCGGGCACGCGGGATGCTGGCCGCCAGCTCTCCCGGATCGCTGGGAGCCGACGTGACCGACGGATCAAGACCGCCCCGGCCCATGCCGCCGGCCTTGCTGTGGAACAGCTCCGCCAAGGTCTTGGCGTCGGCCTCGCGGGCGTCCTCGTCGGCCCCGGCGATCCGGACGGCCAAGGCGTCCGGCAGGCGGTAGCGGCGGGCCAGGCGCTCCCGGTGCAGCTCCGTCTCCAACTCCGTGGCCCGCTCCGCCACCGCCTGGAACTCCTCCGGCGACCGGGCCGCCTTCAGCGCCTCCGCCGTCTCCCGCGCCTTGGTGCGGTACCGGGCCGCCTCCGCCCGTACGGCCTTCAGCTCCACGCGCAGCGCGTCGGTGTCCAGTTCCTGGCCGTCGCCCTGTTCCTCCGGCCGGGCCGGTTCCTCGGGGCCGTTCGCGGCCTCGGTCCGAGCCTGCCCGTCGTCGGCAGGCTCGGAGGTGGTGGGTGTGGTCTCCATGCGGAGCCTCTCCTCAGTTTCGTGATGATTCGATGTGGCGACGCCAGGCCCGCCGGGCTTCCGCGCCGGTCATTCCGCGGGTGACCTCTTGCCATTGGCGGTCGTAGTCGCGGGCCTGCGGGGTCATGAAGTCGTTGCGGGAGTAGATGGGGACCGTCTGGCAGTGGCACCCGTTGTGGTAGCGGGTCAGGTCCTCCAGGGCGACCGGAGGCCGTCGGTTCGCGCGGACCCGACCGTCGGGGGCGCCCTTGGGCTTGCGCCGGCCGCCACCGGCCGCCGTGGACTGGGACGTGTACATGGCGCCCCGGCTGGCGAGCATGGCGCAGAACGCGCACGGGGTGCCGTCGGTCACCCGGGCCCAGCCGACCACCCGCCGGTCCTGCTTCGACGCCTGGTCGATCAGGTCCCGTCCGCCCCGCAAAACCTCGCGGTCGGCTGCTCCGGCGGAAGACCGGCCGGCGGTGTCCACCGCGTCCTCCAGCTCCTGAAGGAACCCGCCGTCGTCCAGCCGCCCCCGGGCCTCGTCGGTGTCCGCCTGGTCCAGGTGCTGGCGGACCTTGGCTGGCCCTTGGGATATGAGGGACGCCACGGCCGCCCGGTCATGATGCTCCTCTGGCTCCTCTGGCCAGTCGAACCCGTCCAACCGGATCTCCTCGCCGTCGTCCGGCTCCGGCGTGCGGATCGTGTCCGCCTGGTCCGCCCAGTCCTCCCGCAGTTCCCCCAAGGTCGTGGTCTCCCCCACGTACTCCCCGGACAGCGGCGGGACCGTGTGCCCGGTCTCCAGGGCCCGGTAAAGGCGGTAGAACGCTGCTGCCTGGTCGCGGGAGCGCCGACGCTCACGGCGGACCAGGGCCAGCATCCAGGCCAGCCACGCAGCTCCGCTCTCCTCCAGGGAGTGCGGGTTCACCCGTGACCAGTGGGCCAGGGCCTGGGACGCGACCTGGGCCCCGATGCGCTCCTGGGCCTGCCAGTGCTCCTCAACGAGGGCGGCCGTGGCCCTACGCAACGCGGGCCCCGGCCGGCTCGGCGGCCACCACGGCGGAGGCCATGCGATCAGCCATCCTCAGGCCGGGGTCGTCGGCCTCCTGAATCTGCGCCCACTCCTCCACGTCCCGTGCCGTCACGCCAGGGATACGCGACCACATCGCACGCGGCGGAACCTGGAGCATCTGCACCGCCTTCCCCAGCGCGTCCACCGTCTGAGACAGGGAGCGCGATTCGGCGTCCTTCCAGAGCACTTCGGCCCGGGGGTCCGGGGCGACGCCGATGACGGTTGAGCACAGGGCCAGCACCTGTTCCCAGGACTCCCCAAGGGAGTGCTGGAACTCGTTGACGGCCCGGGACAGCGCCATCTCGGTGGCGGCCATGGCCTCCGCCGAGAGGTTCGTCAACGACCCGACGCCCAGGTACATCGGCGGGAGCTGGGACAGGGCGGCCATGTGCTTCGTCGCCAGCTCGATGGCGTCCAGGAATCCCGACAGCGGAGTTTCGTCGAGCTGGGAGAACTTGGTGTCCGCGTCCGGGGCGACGAGGAAACGGGAGGCGTCCGCCTGGATCGGGACGACCTGGGGACGCCCGTCCCGGTCGTAAAGGATCTCCCCGGTGTCCGGGTCCCGCCGGAACTCCGGCGCCATGCCGCTGATCGTTCGCACCTTGAACGACCCGAACGTCTGGGCCACCAACAGGTCGAAGACCGTCTGGTTGACCCGGTCCTGGATCGGGATCATCGGCTCCACCACGCCCGTGACCCGGCCCTCCAGGTCGAGGTCCGGCGCGAACCGCACCACCGGGCACACGGTGAAGCCGTGCGGCCGGGACTCCAGCAGCCGAGGCCCCGCCTTGCCACCGACGTAGAGGTCATGAACATGGGTGGCGTCGTACAGCCAGGCCCGCGTCTCCACGCCCTCCCCGTCGGGGACGGTCTCCACCTGAAGCGCCCACAACGGCAGCGCGTCGGCGGCCGGGTCGTCGTACGCCGCGAACAGCATCCGTGGGGACACACCCCGGATCACCGGCCGGTCCGGGGCCGCCGGCTCCGGCAGGACCGTGACGAACGCTTGCCCGTAGGTCAGCGCGGCCCGGTGGACAGGGGTCTGGCGCGAGTCCATTCGCTGGTCCTGCCATACCCGCCACTCCGCAGGCGTCTCCTCCGACAACCCCGGCCCGTCAGCCCCGTCCGTGCTTCGCCGGTACCCGTCCACGGCCATGGCCTGGCTGGGTGTCTTCACCAGCAGCGGGAGCCAATTGGATATCGCCCGCTTCGCCAGCAGCTTGTACTCCTCCGTGGCCGTCCGCGGCGTATACGGGCCGTCGTGCTCCCCACGCATGTACCGGTCGATGCGGTCCAGCCGCTCCCGGTCCGCGCGAAGCCGCGTGAACCCGCGCTCCGCTCGCTCCGTCGGGGAGACGGTGGTGTCGTGCAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP006871|5941542:5966853|5957346_5957688_-|WP_016571207.1|DBSCAN-SWA
MWRGALTPRRAWHLSEHLPPGSALAASLAGGPEHRGWTVQTHLLAALLDAVRFADANNVRVSGGRLKRDPVPVNVPQVKADKHERPRLDLSTHPLAKPIAPGGNSWPAPEAAR
>NZ_CP006871|5941542:5966853|5951599_5952718_-|WP_016571211.1|DBSCAN-SWA
MTTAALPPAGYRFLFTDLRTDQLLDVLPVQQVTFDDYIGKAGTLRGTLAAPDEATAARIKAAVTPGRTALWVERGRDLWWGGIIWTATPATNDRGAVTVALQAATFDSYWDHREIRDTLEAQQADQLDIARNLATYAATKAGGDIGIRIDYTGTAGVRRDRTYSRYDATPVREALDRLAAVDGGFEWRVQVYREAETGERVKRLQLGYPKIRSGAVPVMLTYPGNVLAYSWPQDATGMANTWQSRGATDNQNQAEQSNPLLSTEWSYPEKLTEGWPRLDGHSDYTTVERLTTLDEHAKADLARAKEPVVIPSIQVRLDGEVTPALIGATVRLRIRDTWFSDGLDATFRVVGLSVTPDQRGQQEAAELFLEAT
>NZ_CP006871|5941542:5966853|5949551_5949764_-|WP_045788487.1|DBSCAN-SWA
MIGAREIYDELVALRGDVRSLTQTHEAVTQTLADHESRLRGLERWRYALPLAAVTSLGTLIAALVKAAGA
>NZ_CP006871|5941542:5966853|5960336_5960618_-|WP_016571203.1|DBSCAN-SWA
MATVKPNTDSIVAHLRGVRDAVADELDQRADRVRAVVEAHRHTGALAAHTRVRTNRTDSTVTLEDPAVYAINYGHLTPNGRWVPGIHAIEAGL
>NZ_CP006871|5941542:5966853|5948925_5949501_-|WP_016571215.1|DBSCAN-SWA
MPHPHIALVGKARSGKDTVAQLLVRHASFTRLAFADELKAALVRLNPLVVSCCCYKEHRLKDALEDHGGWEGAKALGEVRRLLQQCGQAVRDRDPDFWVRPVLAQVRHGSEWHMPCVVADARYANELDALRAEGAVVVRVERPGAGLDGDAGTHPSELELDGITPDHVLHNTGTLSELRDSVRALFNKLGD
>NZ_CP006871|5941542:5966853|5962347_5962845_-|WP_016571199.1|DBSCAN-SWA
METTPTTSEPADDGQARTEAANGPEEPARPEEQGDGQELDTDALRVELKAVRAEAARYRTKARETAEALKAARSPEEFQAVAERATELETELHRERLARRYRLPDALAVRIAGADEDAREADAKTLAELFHSKAGGMGRGGLDPSVTSAPSDPGELAASIPRARR
>NZ_CP006871|5941542:5966853|5943500_5945933_-|WP_016571221.1|DBSCAN-SWA
MRTKDLAQFLVRFSEVVEERGEYGVPCPVHDDQRPSLFFRLKEDGRLLVRCWAGCPRDVILAALGMRPADLFDWTPGAGVKASAKPVPGVLDAGALAALAQYVDTTNVAFLDPEHSEARDYVAERFGLDAERAVDLGLGLDYPGLDDRFPYRSTGYLRHPRLTVPLCDFNGRPRGLQGRDLTGHCPARWLSIVSPDGSAWAKYGVLRANSGYATVLITEGPGDGLTGVAVGYDVVMVRGAGLARNAALVAELAAGLGDRDVVLAGDRDTAGAAFTDALADALVQAGVMVRKLEIPTPGDDLTDWRARDPEAFPGHLHAAVRRAPLHVLDVGPEPDTSAVGTDEPRPMPLTDLGNATRLYRQLGGHVRMVPGIGVYKWHGTHWQLIPKEALYADVRAVIHALEGETGHDPEKRARWALKSQDSGRVKAMVEMLASIPGVYATADRFDADPNLLAFKNTVVDLRTGQTRPHDPADMNTAVLDVDYRPDAQAPRWERFLAECHPHAPGMPNFLQVLTGYGITGYGVERCFVMHVGPTTNGKTTFTETLERVFRGITKRADPALFQKRRESGGPRADVVSLRGRRLVISSEWPANMPLDQALMKAVTGDQTITARGVYAREELTFRPVCLVQVDTNYAPDVDATDQALWQRVRVVPWMQDFRGREDKRLKATLASEREGIAAWAVRGAVAWYREHTAGRGLAFPDAVERRTAHYRDTSHPLAGFIGEEYVAQEGAHVPRTATWERYRTWVEECGIRHPMTRNKFYDALRTFPGVRESKVNGTPVLANLADCRSVSRAPVDAGTADIFGQPRSAA
>NZ_CP006871|5941542:5966853|5950898_5951600_-|WP_016571212.1|DBSCAN-SWA
MAIIPQDLTDRIRRLEAELRMLTTAANRRPAMNQVLHGDVKIGEGGSLSVRQPGGRETFRVGEVGPVAGEHALVVRRRDGSEALSVWNGTTAEGQAQALRIKDAQGNELLSEDVVAGGLARPHLPVVMTPAQGADWPSTKATDWTDLQVAWPEVQHPRMEVFAQALANGAGGDIRITVDGQTVASGSTNKAVQATFKIPNYTFGAHPEIKLQARAKANSTVWACVQRLYGVAS
>NZ_CP006871|5941542:5966853|5946883_5947624_-|WP_016571218.1|DBSCAN-SWA
MARTLRVFDTDPNARPKVFTSDYVGRFRAGQQLNGRPVALKAWRITTGDPEVSKTVAALYGGTPEPWETSKEDCVEVLTDTDTVKVIVDGPDAVTFRMALYGMTGKPIHACDGVEFTDPEDPRYGQPCGCPTTLQERKAAAKAGHGPKPDQRMDFRLADAPELGRFRLMTGSWDFMKSLETLWRELEVVGGPALCSLGLELVEFTTKAGVDVAYRKPVLTVHGPASTEAGPAVPSLSKVTADSAPF
>NZ_CP006871|5941542:5966853|5957756_5958080_-|WP_020930424.1|DBSCAN-SWA
MMAEAAAEYEALPLETRAGETIQLRNILMLPDDGLKAARAILARFGETGSEELEELVPKIRDLLLLVADDPAALKTEMQDWPLAVFVRTVGEWQEETQVGEAPRSDS
>NZ_CP006871|5941542:5966853|5958814_5959222_-|WP_037634988.1|DBSCAN-SWA
MRPVLPDVDALVTDALRQVLSGATVRVGWPADWADWLPLVVARRVPGGTATPQGIDVALIDVQCAAVDRRDASRLARTVRVALAEACRAQFRGADGYLSRFEDVSGPAEIRVGDPPAGPDLFRFQAAYRVTARPL
>NZ_CP006871|5941542:5966853|5953785_5954610_-|WP_106966002.1|tail|DBSCAN-SWA
MGETTEYVGEQLTGWDDLPDVESTTVLRPTQHGGWPGQLLAGTRTLQFDFMVLPDSMERYPALLADLRRATAPTQREQDLVVQLAGARRLMRGRVTRRALPADRRYTRGEPYGSVVWECSDPRRYEPQENRVTCGLPAPEPGLDWTDGLDYPLEWGITGSTGTLVAPNLGEAPTHPVVEFRGPVVRPSLLQLHTGWRLEYDITLTESDVLRIDCAEGTAVLNDTASRLYTVTASSVPEQTFTFDPGVSVLAFRAAPGFYDPLASVTVRWRSAFW
>NZ_CP006871|5941542:5966853|5960942_5961296_-|WP_106966383.1|DBSCAN-SWA
MAALEQRLGRELVGEERAQAEAALADASALVRAYGDAWPDPGRAPAVAVAITLAAAERRVRNPEGYRSEVVGGYQYQLPASLPTGGGLTDGEARMIRAAVGASGLFAVPVESLGGAL
>NZ_CP006871|5941542:5966853|5961319_5962258_-|WP_016571200.1|DBSCAN-SWA
MANAFLKSETIAATSLGLLERELVLANLVWSNAGFDFTGAKADSVTVRIPAQLNAREYDWRNDRSSDIVLDELAEDSLTVQLNKDIYSAVAVTDEELTLDIRDFGSQVLQPQVNAVAKAIDAGVANMIETATYSVPAIVVDEKDPFPAFIDARAALNKNEVPTNDRTLLIGADVETALLKSGRLNDVSKSGSDSALRQAMVGNLAGFNLVTSNAINPRSAYAFVPSAFVLATRAPAIPAGVTSGSSQSYNGLAMRWVRDYDAAKLRDRSIVNLFAGFNVMTDPVGGGKNPTKRLVRAVKLDMPTASKPPADK
>NZ_CP006871|5941542:5966853|5960622_5960946_-|WP_016571202.1|DBSCAN-SWA
MSLLDSGPDQVTVYPTADVDDGYGGTKPGPGAPVTIRARVLPTTTDESGEAGYLTGTEYRVYARSLPAGPWSRVEWAGQVWTVVGEPQRFGGSLRLAHDVATIRKRG
>NZ_CP006871|5941542:5966853|5946515_5946779_-|WP_106966004.1|DBSCAN-SWA
MHDFTGQEIREGDTLVYAARRGNSVRMVEAVVLRTYTENYKGRVLPMLKVKPTGNESGWVKRATFRVETVAAEHVAVTVPAEVPAGV
>NZ_CP006871|5941542:5966853|5959218_5959500_-|WP_016571203.1|DBSCAN-SWA
MATVKPNTDSIVAHLRGVRDAVADELDQRADRVRAVVEAHRHTGALAAHTRVRTNRTDSTVTLEDPAVYAINYGHLTPNGRWVPGIHAIEAGL
>NZ_CP006871|5941542:5966853|5946008_5946404_-|WP_016571220.1|DBSCAN-SWA
MSNAAKAKGTRWEREVRHYLNTALGQYVDHWKDVTYPWKDPHDPDNITRPAQTGAKDVGDLHAQPFVIECKAERSIRLADYVRQANREAEHAGFPYGVAVVKAPRRRVEDAYAVMDLITFGRVLQALRHLD
>NZ_CP006871|5941542:5966853|5958210_5958795_-|WP_016571205.1|DBSCAN-SWA
MALIDNAAIVPAGGYIFIADPDTEKPADLADPTKPGGAWESIGHTKLDALPEFGRDGDDPEIKGSWQNAKLRATTPDVTYSVTFQSIQATALTYQLYFGAGPAAIQADKSFRIPATPTPQTKALLVVLVDGTNYLPLYHPRVSLLGSDAVGMSSDDFVSFPIKGTFLGSSKLGGAIGEWAQVAAPEPPPHHDKE
>NZ_CP006871|5941542:5966853|5952714_5953776_-|WP_016571210.1|DBSCAN-SWA
MTVRSGWLVNRDSPGGGQTRADTRLVPVGTWTPQGELTSRGGVVPGGNPFALTAAGAMQCTIGTGRALISGSSVQGAYPVAVTEPETLTIADGDAQYPRKDSVLLRVDDSAYDGSDQSTAALVVARGTPSATPEAPAASGTAEKLYEITVPAGTSAGTGGIDWATAVSDRRRTTVSLGGIQAGGWSLNYGGAYPGQYRDNNRGLERWDGESWRSVAERHYVAVRKTDAYNLAANRYTPVRWSSVDARTDASMWTPTNPTRLVAPVGGLYTVYAQQTWPGGAEQARVTVTKNAGVGEWHMSFVARSNGGQGHATALPLVLQAGDFIEVNVYSATALDNVPGRYSYATLRWEGPA
>NZ_CP006871|5941542:5966853|5954683_5957374_-|WP_016571208.1|DBSCAN-SWA
MAGPGGREVGRLSIRVLPDTSNFAVSLQRYLDRVERRARVQVQAVPDLEGFRERLNAKLARVRARVRVNVDPDLSEFRSRLRERLQGANAGLGVRLEVSEREVARLRRELARIRPPMTIPARVEADRDRLATLARDVSHVGDSSGGAGRKVLSLVGTLGKLSTAASSIPAVAGLSSSIASMAPAAGVAAPAVLALASAGVALKVGMSGLGDALAGDAEAMAELAPAAQDFVTQAKALGPAWDEVKRSVQGSLFQGLGDTLTRTANAVLPVLRTELSGTASALNAMGKDTLATARTLAQDGALGQALSGATRGLQNMKSLPGTVLQGLVQLGAAAAPTWERMTTSMGQGLDRLRAKMDRSFESGAMQRGIEAAVGVAKEFGSTLANIGRTLGNVLGAAADAGGGALQVLSELAATAAKVTATPEAQETFRALFETVSAVGKAVSTILGGALKAVMPLLNTLVTTLAGPVQSAAGTLAPVFVQLAQSLGAGLAPVVKVVAQALAAILPIAAQLISQLAGALGPVLEIVGGLVAKIAGALLTALKPILAQLPSILGPILSVIGELAPILGDLVGQLISALAPALATIGKALGELLVACGPLITALGTLLAGALKALVPVITPVITLVGKVAGVLAELASKYITTIVVPAINAIVALLRGDFSGALDAAKSALSGLASFFGSIFTKIGSVVLSGVSAVVGYFADLASRAWAQVKTMGSNIVSAARSGLSSMGDRISSGISSAVATLRSLPGRARDALGNLGSTLWNAGASLIRGFIDGISSMITSLKNKLGSITSMLPDWKGPAALDARILTPNGRLLLTGFMKGIQDQVPELKRQLGGITADIPAMVGTRPVLPRAEQVRPGPTSGRASTAITIENFHAGDMQPAQVARELDWLMKARG
>NZ_CP006871|5941542:5966853|5947735_5948455_-|WP_106966003.1|DBSCAN-SWA
MTSVLSMLPKGFLPFWAAKEVATAAVDNLGSLVGLAMNDRAGAIDYLKGAPRRVTKAAADIGSAAHDVFERLARGEAVTRVHPDLRPYAEHFREFLDAVQPEFLFLEDAVWSDQHTYAGSFDAIARIGGETVVLDWKTTRSGVHEEVALQLSAYANADRIVKADTGESVPLPEIDAAAVLHVRPEGWKLVPVRHTPELFATFLHLRAVFDWEREGKRGVIGRPVASGGEAETGTQRRAA
>NZ_CP006871|5941542:5966853|5965428_5966853_-|WP_016571197.1|portal|DBSCAN-SWA
MHDTTVSPTERAERGFTRLRADRERLDRIDRYMRGEHDGPYTPRTATEEYKLLAKRAISNWLPLLVKTPSQAMAVDGYRRSTDGADGPGLSEETPAEWRVWQDQRMDSRQTPVHRAALTYGQAFVTVLPEPAAPDRPVIRGVSPRMLFAAYDDPAADALPLWALQVETVPDGEGVETRAWLYDATHVHDLYVGGKAGPRLLESRPHGFTVCPVVRFAPDLDLEGRVTGVVEPMIPIQDRVNQTVFDLLVAQTFGSFKVRTISGMAPEFRRDPDTGEILYDRDGRPQVVPIQADASRFLVAPDADTKFSQLDETPLSGFLDAIELATKHMAALSQLPPMYLGVGSLTNLSAEAMAATEMALSRAVNEFQHSLGESWEQVLALCSTVIGVAPDPRAEVLWKDAESRSLSQTVDALGKAVQMLQVPPRAMWSRIPGVTARDVEEWAQIQEADDPGLRMADRMASAVVAAEPAGARVA
>NZ_CP006871|5941542:5966853|5963932_5964430_-|WP_016571199.1|DBSCAN-SWA
METTPTTSEPADDGQARTEAANGPEEPARPEEQGDGQELDTDALRVELKAVRAEAARYRTKARETAEALKAARSPEEFQAVAERATELETELHRERLARRYRLPDALAVRIAGADEDAREADAKTLAELFHSKAGGMGRGGLDPSVTSAPSDPGELAASIPRARR
>NZ_CP006871|5941542:5966853|5959504_5959828_-|WP_016571202.1|DBSCAN-SWA
MSLLDSGPDQVTVYPTADVDDGYGGTKPGPGAPVTIRARVLPTTTDESGEAGYLTGTEYRVYARSLPAGPWSRVEWAGQVWTVVGEPQRFGGSLRLAHDVATIRKRG
>NZ_CP006871|5941542:5966853|5948673_5948925_-|WP_016571216.1|DBSCAN-SWA
MFDLIRQAIRDNPVRVRTALGALLVLLGHYVPAVADVAVNDQAMDAITFLVILVLGEGASRKVAAKYNPAPVPEESVGDGTGR
>NZ_CP006871|5941542:5966853|5964443_5965436_-|WP_016571198.1|DBSCAN-SWA
MRRATAALVEEHWQAQERIGAQVASQALAHWSRVNPHSLEESGAAWLAWMLALVRRERRRSRDQAAAFYRLYRALETGHTVPPLSGEYVGETTTLGELREDWADQADTIRTPEPDDGEEIRLDGFDWPEEPEEHHDRAAVASLISQGPAKVRQHLDQADTDEARGRLDDGGFLQELEDAVDTAGRSSAGAADREVLRGGRDLIDQASKQDRRVVGWARVTDGTPCAFCAMLASRGAMYTSQSTAAGGGRRKPKGAPDGRVRANRRPPVALEDLTRYHNGCHCQTVPIYSRNDFMTPQARDYDRQWQEVTRGMTGAEARRAWRRHIESSRN
>NZ_CP006871|5941542:5966853|5941542_5943408_-|WP_037635015.1|DBSCAN-SWA
MITHRHQLAGDQTTIHALETEDDVRQARDWLTTHQPRSLAMDTETTGLDTFSTGHRLRTVQYGTADTAFVVPVERGPAFMDLARTVVTRCPELVIHNAAYDLLVLDRHGVSPLETVAPRVRDTKILAHLSDSRQDFEGGVGVSLKPLSAWYVDPAAPDTQAGLTRVFRSYGLTKETGWAQVPYQDEVYQRYAGLDVLLAARLRPHLEQELVRHGIPDTLVEYEHQLMAICAAMERRGMLLDVPYTEGLVNRLQEQAATHSARAARYGVENVNSDRQVVAALQGMGESWEETTGSGAPSVAKEVLLPLADLSDKWERLQVRTPNPLADAVLRAKRASKWRTSYAVAMLANRDAQDRIHPKINTLGAKTGRASVSDPPLQQLPSKGWEIRRSVVAESGAAYFSVDQSSVELVVLAALSQEPRMCQAIRDGRNLHDHTATLMFGPAFTKHQRGLAKIAGLGTSYQGGAATLARQTGLPVSVMRDTLARYVRAYPGIRRWARGLQRHALSNECEIRTPSGRRLVLDRNALYKGVAYLCQSTARDTMGQALLDLHAKGLTQYLNLWVHDEVLGTAPAAEAADIAREVAKTVRMDLFGVPIGTDAEVYGKTWAGGYGLPADWAPKTP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_037635015.1|5941542_5943408_-	DNA polymerase I	A0A2H5BLF8	Streptomyces_phage	3.1e-303	83.1
WP_016571221.1|5943500_5945933_-	primase	A0A2H5BLM3	Streptomyces_phage	0.0e+00	78.4
WP_016571220.1|5946008_5946404_-	hypothetical protein	A0A2H5BLK6	Streptomyces_phage	1.2e-52	75.8
WP_106966004.1|5946515_5946779_-	hypothetical protein	A0A2H5BLF1	Streptomyces_phage	1.4e-31	77.0
WP_016571218.1|5946883_5947624_-	hypothetical protein	A0A2H5BLF0	Streptomyces_phage	3.7e-111	77.2
WP_106966003.1|5947735_5948455_-	hypothetical protein	A0A2H5BLE4	Streptomyces_phage	7.3e-112	82.8
WP_016571216.1|5948673_5948925_-	hypothetical protein	A0A2H5BLL6	Streptomyces_phage	7.6e-16	57.1
WP_016571215.1|5948925_5949501_-	adenylate kinase	A0A2H5BLJ7	Streptomyces_phage	3.4e-59	59.9
WP_045788487.1|5949551_5949764_-	hypothetical protein	A0A2H5BLH6	Streptomyces_phage	1.7e-21	77.9
WP_016571212.1|5950898_5951600_-	hypothetical protein	A0A1J0MC85	Streptomyces_phage	1.3e-44	45.0
WP_016571211.1|5951599_5952718_-	hypothetical protein	A0A2H5BLE2	Streptomyces_phage	1.0e-128	64.1
WP_016571210.1|5952714_5953776_-	hypothetical protein	A0A1J0MCA6	Streptomyces_phage	1.2e-91	49.4
WP_106966002.1|5953785_5954610_-|tail	phage tail protein	A0A2H5BLD4	Streptomyces_phage	3.6e-86	43.8
WP_016571208.1|5954683_5957374_-	hypothetical protein	A0A2H5BLG0	Streptomyces_phage	7.8e-82	65.2
WP_016571207.1|5957346_5957688_-	hypothetical protein	A0A2H5BLD8	Streptomyces_phage	1.3e-34	66.4
WP_020930424.1|5957756_5958080_-	hypothetical protein	A0A2H5BLK7	Streptomyces_phage	3.4e-32	63.6
WP_016571205.1|5958210_5958795_-	hypothetical protein	A0A2H5BLI6	Streptomyces_phage	1.9e-86	80.3
WP_037634988.1|5958814_5959222_-	hypothetical protein	A0A2H5BLG7	Streptomyces_phage	1.0e-49	74.8
WP_016571203.1|5959218_5959500_-	hypothetical protein	A0A2H5BLF7	Streptomyces_phage	9.7e-20	57.4
WP_016571202.1|5959504_5959828_-	hypothetical protein	A0A2H5BLI1	Streptomyces_phage	3.2e-43	79.2
WP_016571203.1|5960336_5960618_-	hypothetical protein	A0A2H5BLF7	Streptomyces_phage	9.7e-20	57.4
WP_016571202.1|5960622_5960946_-	hypothetical protein	A0A2H5BLI1	Streptomyces_phage	3.2e-43	79.2
WP_106966383.1|5960942_5961296_-	hypothetical protein	A0A2H5BLD2	Streptomyces_phage	2.4e-31	63.2
WP_016571200.1|5961319_5962258_-	hypothetical protein	A0A2H5BLD0	Streptomyces_phage	1.3e-129	77.3
WP_016571199.1|5962347_5962845_-	hypothetical protein	A0A2H5BLC4	Streptomyces_phage	1.8e-40	72.2
WP_016571199.1|5963932_5964430_-	hypothetical protein	A0A2H5BLC4	Streptomyces_phage	1.8e-40	72.2
WP_016571198.1|5964443_5965436_-	hypothetical protein	A0A2H5BLE7	Streptomyces_phage	1.9e-134	72.2
WP_016571197.1|5965428_5966853_-|portal	phage portal protein	A0A2H5BLC8	Streptomyces_phage	3.4e-209	78.1

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP006871|7874777:7881696|DBSCAN-SWA
CGTGCAGGGAGAGGGCCCCTCGGCCGGGCAGCGGTGCGCCTTCGTGCGGTTGGGCGGCTGCAACCTGTCCTGCCGCTGGTGCGACACCCCGTACACCTGGGACTGGACCGGAGTGGGCGACTCCGGGGTCGCCTACGACCCCAAGCGGGAACTGCGGCCGATGCCGTGGACCGACGTGCTGCGCGCGCTGCTCGCCTACGAGGTCCCGCTGATCGTGGTCTCCGGGGGCGAACCCCTCAGCCAGCAGCGCCGGTTGCTGCCGCTGCTGCGCGCGCTGACGGAGGCCGGCCGCAAGGTCGAGATCGAGACGAACGGCACCGTGGTGCCGCAGGACGACCTGGTGGCACTCGGCGTGCGGTTCAACGTCTCGCCCAAGCTGTCGCACTCGGGCGATCCGCAGGCGCGGCGGATCGTGCCGGACGCGTTGCGGGCGTTCGCGGCCGTCCCGGGGACCGCCTTCAAATTCGTCTGCCGCACCACGAGCGACCTCGACGAAGTGGCGCAGCTCGTCGACCGGTACGGGACCCGCCCGGTGTGGATCATGCCCGAGGGGCAGGTACCCGCCGAGGTCGGCCAACACCTGTCCGCGCTGGGGGACGACGTCGTGGCACGCGGCTGGAACCTGACCACTCGATTGCATGTTGCCGTCTGGGGCGACAGGAGAGGCGTGTGAGCACAGTGAGCGGAGCCCCCGAACTGGACGTCCTCGACGACTCCGGGCCGCAGGTCCCGGACCCGCTGGAGGATGTCGCGCGCAAGCTGCTGATCGAGATCGGCGAGGACCCGGAACGCGACGGGCTCAAGGAGACGCCGGCCCGCTTCGCCCGCTGGTGGCGGGAGTTCTCCCGCTACGACGCGGGGGCGGTCGACACGCTGTTCCCCCTCCAGACGGAGGGACAACTGGTCATGGTCTCGGACATCAACGTGTGGTCGCTGTGCGAGCACCACCTGCTGCCCTTCTCCTGCTCCCTGACCATCGCCTACCGGCCCAAGGGCGACGTGCTCGGACTGTCGAAGTTCGCCCGGATCGCCCATCGCCACGCGCACCGGCTCCAGGTGCAGGAGCGCCTGGTCCGCGACATCGCGGAGGAGGTCACCAAGGTGACCGGTTCGGTCGACGTCGCGGTCATCGCCACCGGCGAGCACCTGTGCATGAGCATGCGCGGCATCCGTACCCCGGCGGTCATGACGTCCACGGCCTACTCCGGGGTCTTCGAGGAGTACGGGCCGGCCCGTCAGGAGCTCGTGGCGACGGTGTTCCCGTCGCGCAGGTGACCCGCCCCCCGTCCACGATCGACAGGAGTACGCACGTGGCAGTTCGCGACATACGCACCGGGCTCAGCCTGGACGACGTCCTGCTGGTGCCCCGCCGCACCTCGGTGGTGAGCCGCTCGGCGACCGACACCAGCACCGAGCTGGCCGGGATCACCCTGCGGGTGCCGGTCCTCTCCGCCAACACCCCCTGGTGCACCGGCCGGCAGATGGCCGTCGCCATGGCGGTGGCCGGCGGGCTCGGGATCGTCCACCGCATGCAGACCGCCGAGGACCAGGCCGCGGAGGTGGCCGCGGTCAAGGCGACGCCGGTGCCCGAGGGCACGGAGCGGGCCACCGTCGACGCGCAGGGCCGGCTGCGCGCCGGGGCGGCCGTGGGGGTGACCGACGACTATCTGGAGCGGGCCGCCCGGCTCGTCGAGGCGGGAGCGGACGTCCTGGTCACCGACGTCGCGCACGGCCACGCGGACTACGTCCTGGCCTCCGTCGAGAAGCTGCGGGCCCGTTTCCCCGACACGCCGCTGATCGCCGGGAACGTCGCCACCGCCGCCGGCACGAGGGACCTGATCGAGGCCGGCGCCCACGCCGTGAAGGTGGGCATCGGCCCCGGCGGCATCTGCACCACCCGGCTCGTCGCGGGCAGCGGGGTGCCGCAGCTGACCGCGGTCCTCGACTGCGCCGAGGAGGCGGCCGGTTCCGGCGTCCCGGTGATCGCGGACGGCGGGATCAAGGCGCCGGGCGACGTCGTCAAGGCGCTGGCCGCCGGCGGCCACGCGGTGATGCTGGGCAGCGCCCTGGCCGGCGCCGACGAGAGCGCGGCCCGCCTGGTGGAACGCGACGGCGTCCCCGTGAAGGTCAGCACCGGCTTCGTCACGTTCGGCATGCAGCTGACCCTGAAGCGGGCCCGCGGCGAAGAGGTCAGCCGCGAGGAGCTGGACGCGTACACCCCCGAGGGCGTCGAGGCCACCTTCGCCCACACCGGGCCGCTGGCCGCCACCCTGCGGCCGTTCGTCGGCGGACTGCGGTCGGGCATGAGCTACTCCGGGGCGCACACCCTGGCCGAACTGCGCGCGCAGGCCGAGTTCATCCGGGTCACGCCGGCCGGACTGTCGGAGAGCCGCCCGCACGCCCTGGAGCGGACCCAGCAGGTGGCCCTGGACTACGCCCGGGAGGCCACCGGATGACGAACCCTTGGGAGGACGGCCGCTACGGCAGCCCGGAGATGCGTCTGCTGGTCAGTGACCGCAACCGCTACCAGCTCTTCGTACGGGTGGAGGGGGCGTTGGCCGCGGAGCAGGGCCAGTTGGGGGTGATCCCGTCCGAGGCCGCCGGGGCGATCGCCGCCCGGGCCCGCGACCACCGGTGCGACCTGGCGCGGATCGCCGAGATCGAGACGGTGAGCCGGCACGAGCTCTACGCCGTCGTCCAGCAGTTCGCCGAGACCTGCGCGCCCCACGGCCGCTACGTGCACCACGGGGTGACCAGCAGCGACGTCATCGACACCGCGCTGGCGCTCCAACTGGACGCGGCGATCGGCCTCCTGGGCGAACGGCTCGGCGTCCTGATGGCCGCGCTGTGCCGGCAGATCGCCGAGGAGGGCGGGCGGGTGATGATCGGCCGGACCCACGGCCAGCACGCCCAGCCCGTCACCCTGGGGTTCAAACTCGCGGTGTTCCTCGACCAGTTGACCCGCTGCCTGGCGCGGCTGGCGGAGCTGCGCGAGCGCGCCGTGCGGGGCAAGGTCGCCGGTGCGGTCGGTTCGCTGGGCGGACTGGGACCGCAGGGCATGGCGGTGCAGCGGGCGGTGTTGGCCCGGCTGGGCCTGCCGGAGCCGCAGATCTGCGCCCAGGCGGTGGCGCGGGACCGGATCGCGGAGTTCGTCTCCTGGGCCGCGCTGACCGCGGCCTGCCTGGAGAACCTCGCGACCGAGATCCGCAACCTCCAGCGGACGGAGATCGGCGAACTCGCCGAGTCCTTCGCCGAGGGGGACCAGATCGGCAGCTCCGCCATGCCGCACAAGCGCAACCCGGTGCGCAGCGAACGCATCTGCAGCCTGGCCCGGCTGCTGCGGTCGCTGGTCGGCCCCGCGTTGGAGAACGTGGTGACCTGGCACGAACGGGACCTGGCCAACTCCGCCAACGAACGCTTCACCCTGCCGCAGGCGTGCGTGCTGCTCGACGAGATGCTCCTCACCACCACCGCCGTGGTGGACGACCTGAGGGTCTTCCCCGAGCGGATGCGGGAGAACCTCGACCGGTCGCGCCACAGTCACCTCAGCGAGGCGGTGCTGCTGGCCATGGTCGACCGCGGGACGGACCGGCTCGACGCCTACCGGGCCCTGCAACGGGCCAGCGCGCTCGCCGCCCGGGACGACCGCGACCTGGTGGCGGTGCTGGCGGACGACGCGTCGGTGACCGCGGTGCTGCCCGCACCGGACCTCGCGGCCCTGGCCGAGGCGGCCGCGGACACCGGCTTCTGCGACACCCTGGCGCAGGAGACCGTGCGCCGGGCCGAGGAAGCGCTCGCAAAGACGACGGAAGGAGCTCGGACATGCCCGGCACGGTGATCGTCGGTGGCCAGTGGGGTGACGAGGCCAAGGGGAAGATCTCCAGCTATCTGGCGATCCGGGACGAGCCCGCGGTGGCGGTGCGCGCCGGACTGGGGCCCGGCGCCGGCCACACCGTGGTGCACGCCGGACGCACCATGAAACTGCGCCAGTTGCCCAGTGCGGTGATCCGCCCGGCCACCCGCCTCCTGCTGGGCGCCGGCGTGTTGATCCGCCCGGAGGTCCTGTTGCGGGAGATCGCGGAGTTCTCCGCCGAGTCCCGGGTCGGCGTGGACTTCCGCGCCACCGTCATCGACCCCGAGCACGTCGCCGCGGAGGCGGCCGACGCGGGGCTGACCGAACGGGTGCGCAGCACCGGCAGCGGCCACGGCCCGGCCCTGGCCGCCCGCGCCATGCGTGCGGCGCGCCGCGCCGAGGACGTCCCGGAACTCGCCCCCTACCTCACGGACACCGTGCGGGTGGTGAACGACGCGGTCGACGCCGGGGACCGGGTGCACGTCGAAGGCACCAACGGCTTCGGCCTGTCGGTGCTGTACGGCACCTATCCCTACACCGTCGGCAAGGACAGCACGGCGAGCACCGCGGCGGCGGACGCCGGACTGGGCCCCACCGCGATCGACGAGGTGGTGTTGGTCTTCCGGGCCTACCCCACCCGGGTGGGCGCGGGGCCGTTCCGCACCGAGATGACCGAGGCGGAGGCCGAGCGGCTGGGCATCGTCGAGTACGGCACGGTGACCGGGCGGCGGCGCCGGGCCGGCACGTTCGACCTGGACCAGGCACGCGAGGCGGTGCGCGTCAACCGGCCCACCCGGATCGCGCTGACCTTCCTGGACCACGTGGACGCGTCCTGCCGCGCGGTGCGCGCCGGGGAGTTGCCCGAGGCGGCGGCGGCGTTCGTGGCCCGGGTCGAGGAGGGCCTGGGCCGGCCGGTCGACCTGCTCGGGACCGGTCCGGGCACCGCCGACGTGGTGGACCGGTGGAACGGCCGGCCCGCCGGCACGGCCCGCAACGTGACGAGCGGCCAGGGAGGCGACCGATGAGCGGCACACCGATGTGGCGGCGGGACCGGCTGTTGACGATCAGTTGGGAGGCGATGGGCCGGATGCTGGCCGGACTGGCGGACGACGTCCGGGCCAGCGGCTTCGCCCCGACCGTGGTGGCGGGCATCGCCCGCGGCGGGCTGCCGCCGGCCATCGCCCTGGCGAACCTGCTGGCGATCGAGGACTTCCGCATCCTGGGCATCCCCCGCAACACCTCCAACTCCCGGTACAGCGAGCGGGGGGCGGCGGTGCTCAAGTACGTCGTCCCGGAGCGGGAGTTCGGCGGCGCGCGGGTGCTGCTGGTCGACGACATCATGGGCGACGGCGGCACCATGGCCCTGGCCAAGCGCACCGTGGAGGAGCTCGGCGCCGCGGAGGTCCGCACGGTCGCGGTGGTGCGCAACCTGGGCGCCGCCCGACGGGCCGACTTCCAGGCGGTCGAGGTGGACGACTGGACGGTCTTCCCGTGGGAAGCACCGCCCGGGGACAACGAACTCGCCGTACCGTTGCGGGTGTGAGCGACATGGTTGAGGAAATGGGTCGGACAGGGCGGACCACGGTCGTGCTGGACCGGGACGGCACCCTGTTGGACTTCTACGAGATGTTCCACCGCTTCGTCCTGGACCTCCACCGGCAGGAGGGGGTGATTCCGCCACCCCGCGAGGAGATCCTCGGCTTCGGCTACTGGTCCTCGATCACCAGCGGGGCGCTGCACATCGGGTCGGTGCGGGTGCGGGACCGGGTCGACGAGGTGGCCCACCGGTACATGGCGCACGGCACGCTCTACCCCGGGGTGGTGCCGATGCTGTCGGCGCTGTCCGGGGCCGGGGTGCGTCTCGCGCTGGTCAGCTCCTGGGTCGGCACCGAGGCCACCGTGGCCCTGCTGGAGCGCTACGCGGTCCGTCCGTGCTTCGGGCCGATCCTGACCCGGGACGACCTGGACGCGGGGGACGGCCCGGTCTCCGACGCCGACTGCAAGACCGCGTTGGCGCGGCGGGCGTTGGACGGGCTCGGCCACGCGCCCGACCACCGGCTCTACGTCGTCGGCGACACCCCGTCGGACATCGCGTTGGGCCGCCGGTTGGGGGCCGTCGTGGTCGGGGTGCGCACCGGCAACGGCGGCGGACTGCCGGCCGAGGGCACGCCGGAGGGGCCGGACGTCCTGCTCCCGTCGGCCGCGGACCTGGGCCGCCTGATCCTCCAGGCGGAACCGGTGGGGTGAGCCCCCGCCGCCCGCCGAGGGCGTGCCGACGGGCCGGACTCCGTGCGGAGTCCGGCCCGTCGCGGTGCTCGGCCCGTGGGCGGGGCCGGGCGCGCCCGGGGCGTCAGGGCGCCGGGTACGCCGTCACGTCGTCGAGGTAGCCGGTCGGGTCGGCCAACCCGGCGTTGCGGAACGCCTCCCGCCGCTCGTAGCAGGTCCCGCACGTCCCGCAGTGCCGGTCCCCGCCCTTGTAGCAGGACCAGCTGAGTTCCAGCGGGGCGCCCAGCCGGACGCCGTGCGTGGCGATGTCGGTCTTGGCCCAGGAGAGGAACGGTGCCTCGACCTGCGGGACCGCGAAGCCCTCGTTGGCCGTCGCGACCAGTTCGCGCAGCGCGGCGACGAACTCCGGCCGGCAGTCCGGGTAGATGAAGTGGTCGCCGGCGTGCATGCCCAGCGCCACCACCGACGCGCGGTGCGCCACCCCGATCGACACCGCGACGTTCGCCAGCACCGCGTTGCGGTTGGGCACGACGGTGGCCCGCATGGACTGTTCCGCGTAGTGCCCGTCGGGGACGCTGACCCGGTCGTCGGTCAGTGCGGAGCCGCGCAGCAGCGCCCCGTAACCGCGCAGGTCGACCACGTGGTGCTCGGCGCCGAAGTGGGCCGCCACCGCCCGGGCCGCGTCGATCTCGCGGTGGTGGCGCTGCCCGTAGTCGACGGTGACGGCGATCAGCCGGTACTGGAGGGCGGCGTAGTGCGCCATCAGCGTCGTGGAGTCCAGACCTCCGGACAGCACCACCACGGCGGTGAACGGGTCGGTGCGGCTGTCGTCTTCGTCCAT

Protein sequences of DBSCAN-SWA_3

>NZ_CP006871|7874777:7881696|7875472_7876051_+|WP_037634046.1|DBSCAN-SWA
MDVLDDSGPQVPDPLEDVARKLLIEIGEDPERDGLKETPARFARWWREFSRYDAGAVDTLFPLQTEGQLVMVSDINVWSLCEHHLLPFSCSLTIAYRPKGDVLGLSKFARIAHRHAHRLQVQERLVRDIAEEVTKVTGSVDVAVIATGEHLCMSMRGIRTPAVMTSTAYSGVFEEYGPARQELVATVFPSRR
>NZ_CP006871|7874777:7881696|7880168_7880876_+|WP_078486614.1|DBSCAN-SWA
MSDMVEEMGRTGRTTVVLDRDGTLLDFYEMFHRFVLDLHRQEGVIPPPREEILGFGYWSSITSGALHIGSVRVRDRVDEVAHRYMAHGTLYPGVVPMLSALSGAGVRLALVSSWVGTEATVALLERYAVRPCFGPILTRDDLDAGDGPVSDADCKTALARRALDGLGHAPDHRLYVVGDTPSDIALGRRLGAVVVGVRTGNGGGLPAEGTPEGPDVLLPSAADLGRLILQAEPVG
>NZ_CP006871|7874777:7881696|7874777_7875449_+|WP_016577817.1|DBSCAN-SWA
MQGEGPSAGQRCAFVRLGGCNLSCRWCDTPYTWDWTGVGDSGVAYDPKRELRPMPWTDVLRALLAYEVPLIVVSGGEPLSQQRRLLPLLRALTEAGRKVEIETNGTVVPQDDLVALGVRFNVSPKLSHSGDPQARRIVPDALRAFAAVPGTAFKFVCRTTSDLDEVAQLVDRYGTRPVWIMPEGQVPAEVGQHLSALGDDVVARGWNLTTRLHVAVWGDRRGV
>NZ_CP006871|7874777:7881696|7877228_7878614_+|WP_016570262.1|DBSCAN-SWA
MTNPWEDGRYGSPEMRLLVSDRNRYQLFVRVEGALAAEQGQLGVIPSEAAGAIAARARDHRCDLARIAEIETVSRHELYAVVQQFAETCAPHGRYVHHGVTSSDVIDTALALQLDAAIGLLGERLGVLMAALCRQIAEEGGRVMIGRTHGQHAQPVTLGFKLAVFLDQLTRCLARLAELRERAVRGKVAGAVGSLGGLGPQGMAVQRAVLARLGLPEPQICAQAVARDRIAEFVSWAALTAACLENLATEIRNLQRTEIGELAESFAEGDQIGSSAMPHKRNPVRSERICSLARLLRSLVGPALENVVTWHERDLANSANERFTLPQACVLLDEMLLTTTAVVDDLRVFPERMRENLDRSRHSHLSEAVLLAMVDRGTDRLDAYRALQRASALAARDDRDLVAVLADDASVTAVLPAPDLAALAEAAADTGFCDTLAQETVRRAEEALAKTTEGARTCPAR
>NZ_CP006871|7874777:7881696|7879650_7880172_+|WP_016570260.1|DBSCAN-SWA
MSGTPMWRRDRLLTISWEAMGRMLAGLADDVRASGFAPTVVAGIARGGLPPAIALANLLAIEDFRILGIPRNTSNSRYSERGAAVLKYVVPEREFGGARVLLVDDIMGDGGTMALAKRTVEELGAAEVRTVAVVRNLGAARRADFQAVEVDDWTVFPWEAPPGDNELAVPLRV
>NZ_CP006871|7874777:7881696|7880979_7881696_-|WP_016570258.1|DBSCAN-SWA
MDEDDSRTDPFTAVVVLSGGLDSTTLMAHYAALQYRLIAVTVDYGQRHHREIDAARAVAAHFGAEHHVVDLRGYGALLRGSALTDDRVSVPDGHYAEQSMRATVVPNRNAVLANVAVSIGVAHRASVVALGMHAGDHFIYPDCRPEFVAALRELVATANEGFAVPQVEAPFLSWAKTDIATHGVRLGAPLELSWSCYKGGDRHCGTCGTCYERREAFRNAGLADPTGYLDDVTAYPAP
>NZ_CP006871|7874777:7881696|7878598_7879654_+|WP_016570261.1|DBSCAN-SWA
MPGTVIVGGQWGDEAKGKISSYLAIRDEPAVAVRAGLGPGAGHTVVHAGRTMKLRQLPSAVIRPATRLLLGAGVLIRPEVLLREIAEFSAESRVGVDFRATVIDPEHVAAEAADAGLTERVRSTGSGHGPALAARAMRAARRAEDVPELAPYLTDTVRVVNDAVDAGDRVHVEGTNGFGLSVLYGTYPYTVGKDSTASTAAADAGLGPTAIDEVVLVFRAYPTRVGAGPFRTEMTEAEAERLGIVEYGTVTGRRRRAGTFDLDQAREAVRVNRPTRIALTFLDHVDASCRAVRAGELPEAAAAFVARVEEGLGRPVDLLGTGPGTADVVDRWNGRPAGTARNVTSGQGGDR
>NZ_CP006871|7874777:7881696|7876086_7877232_+|WP_020930023.1|DBSCAN-SWA
MAVRDIRTGLSLDDVLLVPRRTSVVSRSATDTSTELAGITLRVPVLSANTPWCTGRQMAVAMAVAGGLGIVHRMQTAEDQAAEVAAVKATPVPEGTERATVDAQGRLRAGAAVGVTDDYLERAARLVEAGADVLVTDVAHGHADYVLASVEKLRARFPDTPLIAGNVATAAGTRDLIEAGAHAVKVGIGPGGICTTRLVAGSGVPQLTAVLDCAEEAAGSGVPVIADGGIKAPGDVVKALAAGGHAVMLGSALAGADESAARLVERDGVPVKVSTGFVTFGMQLTLKRARGEEVSREELDAYTPEGVEATFAHTGPLAATLRPFVGGLRSGMSYSGAHTLAELRAQAEFIRVTPAGLSESRPHALERTQQVALDYAREATG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016577817.1|7874777_7875449_+	7-carboxy-7-deazaguanine synthase QueE	A0A142F2D5	Mycobacterium_phage	5.7e-34	39.4
WP_037634046.1|7875472_7876051_+	GTP cyclohydrolase I	A0A0P0HSD2	Acinetobacter_phage	3.1e-28	44.0
WP_020930023.1|7876086_7877232_+	guanosine monophosphate reductase	A0A1V0SHK8	Klosneuvirus	9.7e-58	34.7
WP_016570262.1|7877228_7878614_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	9.4e-07	24.8
WP_016570261.1|7878598_7879654_+	adenylosuccinate synthetase	A0A0U4IJU7	Arthrobacter_phage	2.6e-25	34.1
WP_016570260.1|7879650_7880172_+	phosphoribosyltransferase	NA	NA	NA	NA
WP_078486614.1|7880168_7880876_+	HAD family hydrolase	NA	NA	NA	NA
WP_016570258.1|7880979_7881696_-	7-cyano-7-deazaguanine synthase QueC	A0A2P1JXV3	Rhodococcus_phage	6.3e-47	45.0