CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP009042	Vibrio cholerae O1 biovar El Tor strain FJ147 chromosome I, complete sequence	0 crisprs	DEDDh,WYL,DinG,csa3,cas3,csx1,RT	0	0	4	0
NZ_CP009041	Vibrio cholerae O1 biovar El Tor strain FJ147 chromosome II, complete sequence	0 crisprs	csa3,cas3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

657633 : 729609

Bacillus_phage(20.0%)

transposase,protease,integrase,tRNA

attL 651649:651664|attR 712990:713005

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
651649:651664	attL	NA	NA	NA	NA
WP_000146472.1\|657633_658821_+\|tRNA	tyrosine--tRNA ligase	NA	NA	NA	NA
WP_000898882.1\|658888_660334_-	serine-type D-Ala-D-Ala carboxypeptidase	NA	NA	NA	NA
WP_001044323.1\|660431_661457_-	porin OmpU	NA	NA	NA	NA
WP_001883448.1\|662011_662485_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_001054291.1\|662561_662858_-	ribosome assembly RNA-binding protein YhbY	NA	NA	NA	NA
WP_000043220.1\|662977_663607_+	23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE	NA	NA	NA	NA
WP_001107450.1\|663716_665663_+\|protease	ATP-dependent zinc metalloprotease FtsH	A0A0P0BXI2	Ostreococcus_lucimarinus_virus	2.3e-120	44.4
WP_000913082.1\|665729_666566_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	3.2e-18	32.6
WP_001281065.1\|666591_667932_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_000495557.1\|668188_668524_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_000147148.1\|668954_669410_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_000031601.1\|669428_670916_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_000192207.1\|670940_673637_+	translation initiation factor IF-2	NA	NA	NA	NA
WP_001123656.1\|673738_674137_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_000124044.1\|674136_675075_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_000055654.1\|675216_675486_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_000462070.1\|675848_677978_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_001883460.1\|678093_679005_+	lipoprotein NlpI	NA	NA	NA	NA
WP_000887847.1\|679103_679511_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000981941.1\|679557_680895_+	sodium-coupled multidrug efflux MATE transporter VcrM	NA	NA	NA	NA
WP_000872504.1\|680947_681826_-	U32 family peptidase	NA	NA	NA	NA
WP_000421327.1\|681837_682851_-	U32 family peptidase	NA	NA	NA	NA
WP_045788694.1\|682958_685013_-	bifunctional diguanylate cyclase/phosphodiesterase	NA	NA	NA	NA
WP_000932672.1\|685245_685773_+	SCP2 domain-containing protein	NA	NA	NA	NA
WP_000908540.1\|685756_686260_+	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	1.7e-19	32.2
WP_000953212.1\|686370_686778_+	DNA polymerase III subunit psi	NA	NA	NA	NA
WP_000214238.1\|686774_687224_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_000160066.1\|687212_689270_-	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	6.9e-14	34.3
WP_000127615.1\|690010_690199_+	hypothetical protein	NA	NA	NA	NA
WP_000211147.1\|690344_692363_+	ATP-binding protein	NA	NA	NA	NA
WP_001218618.1\|692492_693734_-\|integrase	integrase family protein	A0A291AWU1	Escherichia_phage	1.3e-76	39.8
WP_001995600.1\|693735_694005_-	hypothetical protein	NA	NA	NA	NA
WP_000497807.1\|694007_694982_-	ParM/StbA family protein	NA	NA	NA	NA
WP_000348524.1\|695446_695890_+	hypothetical protein	NA	NA	NA	NA
WP_000985631.1\|698063_701042_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_001120888.1\|701459_702953_+\|transposase	IS91-like element ISVsa3 family transposase	NA	NA	NA	NA
WP_001447541.1\|702983_703868_+	DUF3363 domain-containing protein	NA	NA	NA	NA
WP_000214119.1\|704084_705299_+	chloramphenicol/florfenicol efflux MFS transporter FloR	S4TR35	Salmonella_phage	4.2e-19	28.7
WP_001255015.1\|705326_705632_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000480968.1\|706254_707091_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001082316.1\|707090_707894_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	Q75ZG1	Hepacivirus	3.8e-24	34.3
WP_001043260.1\|707954_708770_-	sulfonamide-resistant dihydropteroate synthase Sul2	NA	NA	NA	NA
WP_001122813.1\|710584_711796_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.2e-51	51.4
WP_000116661.1\|712786_713236_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A218MND2	uncultured_virus	4.1e-36	57.1
712990:713005	attR	NA	NA	NA	NA
WP_000182836.1\|713234_713492_+	hypothetical protein	NA	NA	NA	NA
WP_000196209.1\|713875_714781_+	DNA polymerase III subunit epsilon	A0A2H4P6W5	Pseudomonas_phage	3.1e-06	26.4
WP_000284114.1\|714868_715168_+	hypothetical protein	NA	NA	NA	NA
WP_000180270.1\|715485_716406_+	WYL domain-containing protein	NA	NA	NA	NA
WP_000653856.1\|716423_717224_+	DUF1819 family protein	NA	NA	NA	NA
WP_001115853.1\|717207_717756_+	hypothetical protein	NA	NA	NA	NA
WP_000152592.1\|717768_721458_+	BREX system P-loop protein BrxC	NA	NA	NA	NA
WP_000779609.1\|721462_725203_+	BREX-1 system adenine-specific DNA-methyltransferase PglX	NA	NA	NA	NA
WP_000567536.1\|725215_727519_+	PglZ domain-containing protein	NA	NA	NA	NA
WP_000279702.1\|727557_729609_+\|protease	protease Lon-related BREX system protein BrxL	NA	NA	NA	NA

DBSCAN-SWA_2

884635 : 891828

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000775253.1\|884635_885850_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5
WP_000331703.1\|885886_886270_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_000301571.1\|886330_886654_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_001105747.1\|886702_887218_+	co-chaperone HscB	NA	NA	NA	NA
WP_001196560.1\|887241_889092_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.3e-106	41.1
WP_001124187.1\|889105_889444_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_000872176.1\|889492_889687_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_000107237.1\|889906_891196_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
WP_001162850.1\|891399_891828_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_3

1647438 : 1662653

Vibrio_phage(58.82%)

coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000053920.1\|1647438_1647663_-	RstC protein	U5TMI6	Satellite_phage	1.1e-34	100.0
WP_001911551.1\|1647756_1648107_-	hypothetical protein	U5TMH5	Satellite_phage	1.0e-63	100.0
WP_000743997.1\|1648108_1649188_-	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000693566.1\|1649313_1649652_+	helix-turn-helix transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
WP_000593519.1\|1650253_1650628_-	cholera enterotoxin binding subunit CtxB	A0A142I6Y1	Vibrio_phage	5.9e-65	100.0
WP_001881225.1\|1650624_1651401_-	cholera enterotoxin catalytic subunit CtxA	A0A142I6Y0	Vibrio_phage	1.3e-151	100.0
WP_000021616.1\|1651499_1652699_-	zonula occludens toxin ZOT	A0A142I6Z1	Vibrio_phage	5.3e-240	100.0
WP_000979342.1\|1652695_1652989_-	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
WP_001268534.1\|1652985_1654173_-\|coat	minor coat protein pIII	A0A142I701	Vibrio_phage	1.4e-200	100.0
WP_000493022.1\|1654279_1654528_-	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
WP_001911548.1\|1654663_1655023_-	hypothetical protein	A0A0N9HE73	Vibrio_phage	4.4e-65	100.0
WP_000743997.1\|1655024_1656104_-	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000693566.1\|1656229_1656568_+	helix-turn-helix transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
WP_000170634.1\|1657057_1657642_-	DNA-binding protein	E3U9I9	Vibrio_phage	6.4e-114	100.0
WP_001161489.1\|1657634_1657802_-	hypothetical protein	E3U9J0	Vibrio_phage	2.3e-13	100.0
WP_001052672.1\|1657879_1658572_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000512956.1\|1658701_1658971_-	hypothetical protein	NA	NA	NA	NA
WP_001881266.1\|1658990_1660559_-	replication protein	A7BJY2	Enterobacteria_phage	2.7e-58	32.3
WP_000005769.1\|1660735_1661287_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001161489.1\|1662485_1662653_-	hypothetical protein	E3U9J0	Vibrio_phage	2.3e-13	100.0

DBSCAN-SWA_4

2506071 : 2512688

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864130.1\|2506071_2506542_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7
WP_045788700.1\|2506806_2507916_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	8.8e-64	39.8
WP_000493874.1\|2507956_2508610_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001131994.1\|2508614_2509718_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	33.1
WP_000543544.1\|2509743_2510193_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_000366574.1\|2510292_2511543_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
WP_000210573.1\|2511554_2512688_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage