CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016112	Methylomicrobium alcaliphilum 20Z, complete genome	5 crisprs	csa3,WYL,DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,cas6,RT,DinG,cas6e,cse2gr11,cas8e	1	32	6	0
NC_016108	Methylomicrobium alcaliphilum 20Z plasmid MEALZ_p, complete sequence	0 crisprs	DEDDh	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_016112_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016112_1

1109992-1110086

Orphan

Consensus_repeat	Method
TTCCTCGTTCCCAAGCTCCGGCTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_016112_1

>merge|NC_016112|1|1109992-1110086|CRISPRCasFinder
TTCCTCGTTCCCAAGCTCCGGCTTGAGAACGCCTACAGGAAAAAGGGGTCAGGTCTAGAATGAATGCGTTTTCCTCGTTCCCAAGCTCTGGCTTG

>NC_016112|1|1|1109992-1110086|CRISPRCasFinder
TTCCTCGTTCCCAAGCTCCGGCTTG	AGAACGCCTACAGGAAAAAGGGGTCAGGTCTAGAATGAATGCGTT
TTCCTCGTTCCCAAGCTCTGGCTTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_016112.1\|WP_014147474.1\|1118408_1119071_-\|Fe2+-dependent-dioxygenase	unknown	unknown	gnl\|CDD\|235483
NC_016112.1\|WP_014147458.1\|1088297_1090289_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372673
NC_016112.1\|WP_014147463.1\|1100021_1100261_-\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014147461.1\|1094352_1095915_+\|TolC-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|236529
NC_016112.1\|WP_014146713.1\|1111999_1112746_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|181681
NC_016112.1\|WP_014147467.1\|1109020_1109893_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237864
NC_016112.1\|WP_014147479.1\|1123966_1124275_-\|flagellar-biosynthesis-anti-sigma-factor-FlgM	unknown	unknown	gnl\|CDD\|274802
NC_016112.1\|WP_014147459.1\|1091339_1093043_+\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969
NC_016112.1\|WP_014147472.1\|1116578_1117805_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NC_016112.1\|WP_014146712.1\|1110453_1112013_+\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NC_016112.1\|WP_014147478.1\|1123469_1123970_-\|flagellar-protein-FlgN	unknown	unknown	gnl\|CDD\|377465
NC_016112.1\|WP_014147470.1\|1115243_1115741_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237177
NC_016112.1\|WP_046060990.1\|1082755_1086673_+\|FAD/FMN-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|378859
NC_016112.1\|WP_014147464.1\|1100486_1101308_-\|SapC-family-protein	unknown	unknown	gnl\|CDD\|377801
NC_016112.1\|WP_014147460.1\|1093058_1094384_+\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902
NC_016112.1\|WP_162472919.1\|1120863_1121895_+\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014147473.1\|1117885_1118323_-\|transposase	unknown	unknown	gnl\|CDD\|226192
NC_016112.1\|WP_014147466.1\|1102327_1108873_+\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014147462.1\|1096362_1099050_-\|calcium-binding-protein	unknown	unknown	gnl\|CDD\|225483
NC_016112.1\|WP_014147471.1\|1116027_1116399_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_016112.1\|WP_014147474.1\|1118408_1119071_-\|Fe2+-dependent-dioxygenase	gnl\|CDD\|235483	PRK05467, PRK05467, Fe(II)-dependent oxygenase superfamily protein; Provisional.	5.94435e-85
NC_016112.1\|WP_014147458.1\|1088297_1090289_-\|hypothetical-protein	gnl\|CDD\|372673	pfam13688, Reprolysin_5, Metallo-peptidase family M12.	5.64187e-13
NC_016112.1\|WP_014147461.1\|1094352_1095915_+\|TolC-family-outer-membrane-protein	gnl\|CDD\|236529	PRK09465, tolC, outer membrane channel protein; Reviewed.	8.67399e-68
NC_016112.1\|WP_014146713.1\|1111999_1112746_+\|ATP-binding-protein	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	6.35141e-67
NC_016112.1\|WP_014147467.1\|1109020_1109893_+\|hypothetical-protein	gnl\|CDD\|237864	PRK14950, PRK14950, DNA polymerase III subunits gamma and tau; Provisional.	0.00106747
NC_016112.1\|WP_014147479.1\|1123966_1124275_-\|flagellar-biosynthesis-anti-sigma-factor-FlgM	gnl\|CDD\|274802	TIGR03824, FlgM_jcvi, flagellar biosynthesis anti-sigma factor FlgM. FlgM interacts with and inhibits the alternative sigma factor sigma(28) FliA. The C-terminus of FlgM contains the sigma(28)-binding domain.	2.27742e-14
NC_016112.1\|WP_014147459.1\|1091339_1093043_+\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NC_016112.1\|WP_014147472.1\|1116578_1117805_-\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	5.77943e-87
NC_016112.1\|WP_014146712.1\|1110453_1112013_+\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.51264e-24
NC_016112.1\|WP_014147478.1\|1123469_1123970_-\|flagellar-protein-FlgN	gnl\|CDD\|377465	pfam05130, FlgN, FlgN protein. This family includes the FlgN protein and export chaperone involved in flagellar synthesis.	4.81849e-17
NC_016112.1\|WP_014147470.1\|1115243_1115741_+\|hypothetical-protein	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	1.72336e-05
NC_016112.1\|WP_046060990.1\|1082755_1086673_+\|FAD/FMN-binding-oxidoreductase	gnl\|CDD\|378859	pfam12447, DUF3683, Protein of unknown function (DUF3683). This domain family is found in bacteria, and is approximately 120 amino acids in length. The family is found in association with pfam02754, pfam01565, pfam02913.	1.04427e-64
NC_016112.1\|WP_014147464.1\|1100486_1101308_-\|SapC-family-protein	gnl\|CDD\|377801	pfam07277, SapC, SapC. This family contains a number of bacterial SapC proteins approximately 250 residues long. In Campylobacter fetus, SapC forms part of a paracrystalline surface layer (S-layer) that confers serum resistance.	4.28851e-69
NC_016112.1\|WP_014147460.1\|1093058_1094384_+\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	6.56284e-120
NC_016112.1\|WP_014147473.1\|1117885_1118323_-\|transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.06326e-08
NC_016112.1\|WP_014147462.1\|1096362_1099050_-\|calcium-binding-protein	gnl\|CDD\|225483	COG2931, COG2931, RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism].	6.13307e-12

>NC_016112.1|WP_014147467.1|1109020_1109893_+|hypothetical-protein
MAFFGNSPTIASSSNFGSAPQKAAPSFGPAPEKAVPSFGPAPEKAAPSFGPPPVKSDAPSFGPPPEKAAPSFGPAPQVGDSYMADDPVKGGSYWQTQTQTHYIFDFTSIPAELESLGQFSLIAEGADVDIPLDTQGRSFGLLQSRNVQAAEIDIFLGLDAGTLNSLTPSTATNGAVIKFTVPSAKDLEMIRFDWNFVNNESGTYDDFAFYYISDGQIGVLSSSSQINFASSTGWQQMLVDDLEIDGPVSVAFGVLNVLDTAVDAYLGVDQVELIGVSFAPDISVGTSFWG
>NC_016112.1|WP_014147466.1|1102327_1108873_+|hypothetical-protein
MATLSVDIAQSYMETLRSYGLEFNIRQTNNLTNRIINRLENRGHTPEQVADWLMSRVAVKQQLRKLVKQGELAEFDLDGNGRLNRSELLNAMSALSETAVEEAPVEDPTTPKPPADPSITTLTLTEIPTQRTATLKWNNVDADLAIDFMQDVLKLDLNRLGWMEDGQLTVNIDNIAISDSDSNSDINIGMVDGEEFLFSVNTPVALYTNIIFDLKQNDDVIQTGIVLTPTENNGGSFENGITSDADNHIIAGRPELLHGAYIDGGGGYNTLEVDMKGFFAQPFQLLNIQEIHVQNLPNVYSFDQTIFSDTEGDYFANFPIPTNLDGDDSILDLSRATSLERLVINEARFPGSANALGDLYLVGIKADAVARLEGNFTEDVNLFYGRGLGNAINLEFANVTMSDSEGGGELVLGHNAGTVNLLSEGRLNVLESVDFGSFLRELTITGTGELVIDDALAFAFGEVHIDASANTGGIRLKVDSVADGSSLSNEIGFSAVLDEVTIKGSQGRDVIEISGTAAGVLLDIDTGAGRDTVFLTDDTLSAGAGSVITGDNLTVVVTATADLRKADVVGVDRFVLNAGPAAAGNLVLTQTQVEAMDAGVFTAAHNTIAVLSVEITEAGTVLSDLIDLSALSSDVKLAFNVVKGASLEMTAEELHKYVAFEGIDATMAGHLVITGAGLGFDPEDQSDYDTGGTIANYGLTPDQNISIIRDPNGFERPAPDTNTDILTIDTTGGITIGANALSDDDAFSTNATTLIIEGAGDITFNAPLEMLLDNYTIDFSGLTGNLNGLTILDFQNITDGNDPSDWGQIIGNPDVNTRINVVIEDGKEVGDDSLGNANGGLKSSGVETYVVLGTVGETYTFNVCDTTQGLEVLGFRGLGDVTFNQINWGTNLLLEGDGFENFGDIPKAFANPNQSNIGSIEANYFFDGATVDVAINNQGQALGTTSTGAARPLVVESIVVNGAETVNLAIEDGSAWIKSVDGSVLEDLTVTSDFHVTLSLIAANSDLESIDGSGVVGVMALEISDVDGAGDPTALTVDLSSTELSGIDQIDLGPLADLTLNIDQIEDIGTANIAFTGTAAQAQNDPATLNIGQFAEQEFDITTVGLEAGVELGTVTFVANAGEITMHPDTNLSGATAIVIPEGTTVNMTAAQYEQIVDGGNGSSFSGLGVLNITDLLGEPELDTNGDPIPGAFASDINLSGVPVEMMGSISLAAGVDSMRLTGNIGIAQFEEREIADPDNTDFVSVQTSHNFHELTGETQGFSFVLAEDQNLIFTTEAQAHNRVVEGDGSKVTLAFAVLLDSQVNFNTLGGTLAVDGLNLAYYSDLTDLEVLQALVAGTNVEQILGNLDENTVVQISEFIAGANFANPTFRDVEVLEGVTVAGGLVFENLNDELPDSLKLTELSLSLLGDATITGTVDISGAPLLDQGFETLTINSLGDDPNTINNVVATGNDLIDVVINAEQDLSVQTITLSFVPKTPGQTSDATLTVNGDADVTIKTLDSTDPDINVVNIDNNLTGGATLTFTGGSAAFEGDDTDSLILTGAGNTVFDTEGASTGGIDSDSLSLIDASEHTGDLDLGRIISVDEANFSLLTSAGNASATLQATMNDQGFNAAVLAYNAALAADPVVPGNVTAALTALTTAAGLLGFVDANEDPLAFTQANAADLIAEFRPEWNFELGANTELTIDGDDIVGADFVAGALVISGGKLIIEGEVDLRDLAVLDISDVEIELAAGARILMTDEQFDALDNVTFSGPGQTLEVDDALLAELSIVNDITDIRGVTEIQLEEGLVEDITMTAEQARIATVVDADGNPVLVDFDVDPTVIDAAGDPVEAGDFRTLTGSVVTVEVTGNDDLTDLAGLNRIEIVSDDLVDLKVALDLDGANNQVAALQTAAGGAFDGTFFDVLSNFTVEASFEVLSQFDPETTLFVANPIVEDVNFDIVRDVNGDVTSVSVSGGSSLGFAQSDAGFQELLEAGQVTEVVFENVGSLNSILVSGNFVGSYDAGGIFYESTFEFGANAGSVAEGVGTDGNIFTIAEFTAGAAASDILDFTAMPVDNTNTAPATGHEFIAVGTEASIGDDATIIVFTAGVAADAATIVTQFADGAGDFRSADATARNADFAIDSQLIFLIDDGAGNTGVWYWDDTVGAVGDGIVDADELSQIAQLTGVVTAELTVDNFVLA
>NC_016112.1|WP_014147464.1|1100486_1101308_-|SapC-family-protein
MNRWQLLDTKAHSQAGWQKFTHYAFASQDVYCPILMAELTQTLPYYSLAFLPVSSTEPVKFQLVALLGLRPNRNVYLDKHGKWLAPYVPSYFRGYPFSLLPDEHGKAALAVDITSPLLHNPAQPEDTLLYQESGELTEAAGQILNFLTQRLQNQQVTQVLTDALQQAELIQPWTISWQPNSNDADPEKAKKQQNLGGFYQIDEERLRSLSPETYQSLAKNSALGLAYAQLFSQARLQDLRYREHKALSDAQPTPSLDFDALFGTKDDTLKFNF
>NC_016112.1|WP_014147463.1|1100021_1100261_-|hypothetical-protein
MSEANKQIVTINGIEYDLNDLSENAKNQINNLRVTDAEIQRLNTLLGIAQTARAAYARVLNDELAKDGKEIYPASGMAN
>NC_016112.1|WP_014147462.1|1096362_1099050_-|calcium-binding-protein
MSTIPTDGRDIFYVTPGNQTIDGKAGLDVVFFNGSSTDYTIEVNEKEVIVTHINGNDGSNRLINIEKIHFYGDNKQILLSQETLVNTLTAGTQQASTVLAYPDGGFINFWQGPDGYYFRKFDTNGRGIGIEQRILSGIGEGANVSPALFSDGSIVLAWSAPDADGSGVYVQLFDADGKSPSNIFRANDTITDDQDLPAIAVLQNDRFVVAWSSSNQGDSLQNGVSMGSTPNQTGVFSQLFDKFGNPLGWETKISDSGGSDAFVTALADGGYVIGYEAISAISEQMLIFAKRFDNDGQFKNFLTADDSGIAINATFETTDPLVGNPDFNELASAQKFPTAAQLNNGNIVVVWQAPRDVYPILDDPLDAHDFSIVARIYNANGQVLTDEIEVNTFTTYDQTHPTVAALTGGGFVVVWQSMLQDESYWGVYGQRFNANGTKVSGEFQVNTTAHDSQQQPTVIGLSDGGFVVSWEAEYQDGHQQGVFQDGDAATEIVMQRYNAQGIPLGRSLSGGSGDDTIIVNGAIGVDLSGAAGNDELIGGDGNDVIRGGRGNNILNGGAGDDILIGGPGNDIFIGSPGNNTIIGGGGSNILKLEGSVNDYELSGAPGNYTLLGENQTYTIRGVGLLEFSSGEIIPLVGDVDQGGSPGIGITVEDRDTTTANVLTGTDFDDILIGGNIRGEPDILQGGLGNDLYIALGNRLVIFDTGGNNTLEVASGIDLSQPHRGPIKGLEYIDNVTLTGNRNLKLVGNDDNNILKGNDGNNRIFGGGGDDIIYGGLGRNRLSGGPGTDTFVFDTQPGRQNRDFIIDFSNDILKFSSAIYSGLDPNEDGNINFISAPGLNRAHTNTASFLVYNTKTGILYYDAENSTRAEPIVKVGIVDEGTFTAANLTVADFEFF
>NC_016112.1|WP_014147461.1|1094352_1095915_+|TolC-family-outer-membrane-protein
MPLRAHSLKINPMNKLKHGLLCLLTASTYNAGAEDLLTIYRQALEADPQLRSARLQAEIGSAQKGQALGQMLPQINGTANWSKNEQKIFAQGGAINNSYPGTRYFLSLNQTLVDFAKFWDWRRASKVEDQYAAEAIEAQNELMYKVVERYFDWLQANDELNFTRSEKQSTKKQLEQVRKQYAKQMLKITDVYALEARLDQLAAEEIMAESELVKAEESLRELTGVRPDQPYGLQDDVEFKKIEGDLKDWIAMAQSQNPAMMAKTIAIEAAENNVAVQKSKYMPVVDLQLNYFDTDTGFQSTQTPQIQTQVAAININVPIFSGGTTTHQLFEAQHRLEQSKNDNEATLRALVKETSDAFLSSNASVRHIKAAQKALESSVKSRESMERGLFYGVVTVSDLIQAQQSEYMSKRDLSIARYTYIKNRIRFLRSIGSVNENNIFEINEWLDVTEQEVNAQPMSTVALPHANGEKLNATQPSRHDAPPQEMAQIPQDEQQMEWDDETMEKVLREIKNSRNMQGTE
>NC_016112.1|WP_014147460.1|1093058_1094384_+|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MSENSALINAEPTALHTDDKPIRLIGAIIVLATFGVFGGWAFLAPLDSSALATGVVVVKSYKKTVQHLDGGIVDRILAQDGDLVQAGQLLVILDDTQIKAQLGIAYSQKIALAAQVARLEAERDLLPEIVFPDFLETPVDPRAIEATQAERNVFRARKNAYQGEIAVLEQRIGQIKSKINGLRSQIASKQILVKSYAEEIKDLQELLAEGFADRQRLRDLERSHAQQTGEIAQLQSEVATNEIQISETRLQILQTQKQFQQDVVTKLSEAKAALNDAEERVTANRDKLDRIAIKAPATGMVLGLSVHTEGGVIVPGDPILDIVPKDVELIIEARVSPLDIDRVSVGLQSEVRFSAFKQATTPKMEGKVIHLSADSFIDERTGESYYQAHIELTPESQIDLGELQLLPGMPVEVLINTGERTLVEYLSQPITNAIARSFIED
>NC_016112.1|WP_014147459.1|1091339_1093043_+|type-I-secretion-system-permease/ATPase
MKVTEKSDLEDALKLCKSAFLSAAGFSMLINFLMITPSIYMLQVYDRVVSTGNKSTLVMLTLIVLGLYVTLAALEWVRSQILVRVSTRLETLLNQRLFQVAFKQALLSGGQRATTQPLDDLTGLRQFLTGNGLFAFFDAPWMPFYLGLLFLFHPLYGWFSVVTAILLCLVALANEKVTSKTLSEANTTNIATRGMLQKNLRNAEVIESMGMLGNIRRRWMSGAVKMLDLQAVASSRAGILTSLSKFIRISSQSLILGLGAYLVIEREISPGLMIAGSILMGRALAPIDLMIGTWKGFINARDQYGRLNAILLQIPADSERMQLPDPKGNIQLENAVVVPPGSKTPALKGINVTIDSGDIVGIIGPSGAGKSTMARAVLGIWPTANGAIRLDGAEVFQWDREHLGGFIGYLPQDIELFEGTISENIARFGEIDSQKVVEAAKMADVHELILQLPEGYDTVIGAGGGTLSGGQRQRIGLARAIYGNPVLVVLDEPNSNLDDQGESALEKALMQLKQKNTTVLIITHRKNVLDKADKLLILKDGVLAAYGPKNQVLAHLQQQASSAAAKS
>NC_016112.1|WP_014147458.1|1088297_1090289_-|hypothetical-protein
MTDPVIKEEPHEIYHVIKHKTLHESASAIANRSGIVFKIDDAIKDDIITKKLAADHWQIAVEQLLQNYNYVIEFDQGNVKTVIISGRNGSEVADDDVTFSEPLVIEPVFAEKLPNKYRHYNPGSVMPIDLPMAKLNAMSIGGRLTLDLPIGQYDIEHDNKIEHQNGPLTWIGHLAEEGKGYRFFVSQGEAGIIGNVYTPDGEYLIDSVEGLTVLVDLERSGLQKARQHEHDTMLPPPESLIPVMNNQPLLRVEGLKESAELARARADQLASEAESALAEYEQQRDYVEQTTRQVEVLRDSFNQAKENRLAARLTLNQSRANNASREEIRLARLTLRAARVELRAARRELRKTLAEHRKATRIANRLHRIYLRKQSLADNAEADAKNAEAAYAEYLAALDSPNDTPLDKPIDPPNETSNTVVDLMVLYTTGKQTAEYARQRIQFLVDLSNQALLDSGIKMELRLVHTRATSYIESNSNSRALTDLAFDRGAFSGTAALRNQYGADVVLLFRPLYGQTSGSCGEAYIGFANGGGGIPNFAFATVSDGQSKDANTRSYCGTETFPHEVGHSFGLVHDREFSNVAGKFPYSYAWGIDRRFGTVMSYYGPSLPLFATPLLPRACDSSPCGFPEHHPNASDQTRTVNHTAPIVADYRPTTVLLPIIDPD
>NC_016112.1|WP_046060990.1|1082755_1086673_+|FAD/FMN-binding-oxidoreductase
MSVDSELSPFVADAPSERLREIPYNYTSFSDREIVIRLLGEENWQIIESLRGERMTGRSARMLFEVLGDIWAVQRNPYLEDDLLNNRKRRKALLDALRHRLRQMEKRHAEYENEYPDRARRVALLIEATHQAVNEFEAHFDRTREMRRKALALFSKHTHKDNIGFDGFARVSHVTDATDWRVEYPFVVLYPTSEKEVGQLVRDCIKLGLTIIPRGGGTGYTGGAVPLTPYSAVINTEKLLDMGPIEPQSQLPGVEQTYATIHTGAGVVTRRVMDMAENAGLVFACDPTSADASCIGGNVAMNAGGKKAVLWGTALDNLVSWRMVTPDGNWLEVERIHHNFGKIHDQELVTFALKRFDAKAKELLSEERLEIPGAKFRRDGLGKDVTDKFLGGLPGIQKEGCDGIITSARWILHKMPAYTRTFCLEFFGQVRDSVPAIVEIRDFLEALPKSGNDRVMLAGLEHLDERYVKAVGYAGKAKHRGRPKMVLIGDIVGDDDHQVALAASEVVRLCNARGAEGFVAVSPESRRTFWLDRARTAAIAKHTNAFKINEDVVIPLPRMGDYCDGIERINIELSLRNKLRLCDALIDLFEGDLPLRSYEDGVDKTDLIGERRGHALMVVAEVRERWQWLYDNLDLPLPQAEALFSQYGIVAGELTNLTEQPTLFHRLQDYSLMVSWKQELLPRLKEIFVGDNFRPVVERIEATHKDVLRGRVFVALHMHAGDGNVHTNLPVNSDNYEMLQEANAAVARIMALARSLGGVISGEHGIGITKYEFLTDEELAGFHDYKQRIDPEGRFNRGKLMPGSDLSSAYTTSFNLMGFESLIMQQSDIGAISDSVKDCLRCGKCKPVCSTHVPRANLLYSPRNKILATSLLIEAFLYEEQTRRGISITHWKEFEDVSDHCTVCHKCFNPCPVDIDFGDVSMNMRNLLRKMGKQSFNPVKTAAIAFLSTGRPSSVKLMRKLLIEWSYKAQRLGNFFLRPWGRAQLKRPPSSTGKPAMKEYVIHFTNRKMPGKLPSKTSRALLGIESDQIVPIIRDPNKTRTDSEAVFYFPGCGSERLFSQVGLATQAMLYEIGVQTVLPPGYLCCGFPQRAAGQFDKAQQITTDNRVLFHRVATTLNYLDIKTVVVSCGTCLDQLVDYEFDKIFPGCRMIDIHEYLLEKGVKLEGVNGRRYLYHDPCHSPMQQQDAMKTVNGLLGAPVNKSERCCGESGTLAVARPDISTQVRYRKSVELHRDTAKLRADDYDGPVKMLTSCPSCLQGLQRYKGDVDQLEVDYIVVEIARHVLGEDWMKSYIKQAAKGGIERVLV
>NC_016112.1|WP_014146712.1|1110453_1112013_+|IS21-family-transposase
MIHQIKALYNDGNGLSERQIASQLGISRNTVSKYLKLSAADISALQEEISRGKKLDDYRDYIIQLLQTYPGLSAVKVLRKLKAKVDDLAVSDRSVRRYIQALKQEISFKQARYYEPVLDMVPGEQCQVDGGELRDVMIGGVATTVYFMVFVLSYSRLMHVSICAKPIDTEMLIRQHDAAFRYFGGMPQECVYDQTKLVVISEVFRELRLNQRFHQYATAAGFTIRACEGYDPESKGKVEAGVKYVKQNALYGETFTDWDALKAHMTDWLDGIANQRRHGTTGQQPAIHYAANEQGHMRAYLTPSCVDATASQARITRKADKTGLIAWQSNKYSVPMAYQCARVAVHEANGVIQISDLSTHKVIAEHAVCLEKGQIIKNRHHYRDMSLRIETLEKDLHELLPSPAVVTQLCALLKASSPKIYKDQLAGAKQVLTEQIKQQGAIPEAVLTRLIDTPRLTASGLKERLEAWRQSVGRSDDSDALSMPPSEQATAAIKQECPLARYRALNGHSAGQGESHAIH
>NC_016112.1|WP_014146713.1|1111999_1112746_+|ATP-binding-protein
MPSIDQIARQYRSLCLTAIAEHLPTLLGQAETHESSYLQFAESLVEHEQRQRNAKRIEQNRKRAGFPLLKSLEEFDYRFQTTISKREVNSLLDFGFIDNRDNVVFIGPPGVGKTHLAIGIGLKAIDAGYKVSFNTALGLMEVLELAELKGELKKKINQLLKFDVLIIDELGYLPMNKQGMHNLFQLINALYEYRSVILTTNKEFTNWGEFFIDDNVAVPIVDRIIHHSHIFMLGGESYRLKSKLNQAS
>NC_016112.1|WP_014147470.1|1115243_1115741_+|hypothetical-protein
MALAAQDIEQIEAIVLRVLAERTESKSGTVRYDLELRERFVRVEEELKHQRELMLEGFKQMEKRFEQVDKRFEQVDKRFEQVDKRFEQVDKRFEQVDKRFEQLDKRFEVMQLEMNKRFEQVDKRFEQQHHEIMVLHQEIKVLMRWGFGALIGLSGLIVGLFRLMV
>NC_016112.1|WP_014147471.1|1116027_1116399_+|hypothetical-protein
MALAQDDIDHIQWLIKKAISEASEISNANVRYELDLRERTIRVEEELKHQRELMIESFKQVEKRFEQVDKRFEQVHKRFEAIQTSMDKRFDELLKRHDQQFFWLLGFIATGVGLVIASLRYLK
>NC_016112.1|WP_014147472.1|1116578_1117805_-|ISL3-family-transposase
MNSETLFSMALGLQPPWQVKAVTFSTDELARSELHLHIDFVTGSRFLDDANNLCPVHDTVERQWQHLSFFEHTCYLHCAVPRITTTDGKVRTVDVPWHGRQWFYPVIRSLSASLIEREMPVNRVAEILKVNPQRIWTIFNHWISKAKAADDPSTITKLGVDETSTKKGHHYVTLGVDLDEARVIHVTEGKGKATLQSIQQHLEDKGVDKEQVEQISMDLSPSFIAGAAESFPSAQITFDRFHVVKLLNEAMNQVRIAERKEHDALKGHKYTFLKNRENLSDKKEKELDELIQLYPTLGEVNRLKVLFNDLWEMPDKPTAEAFLRQWCDAVDAAKIPAFIKFANTVRGHWSGIVHFVESLISNGILEGINSKIQLAKRRARAYRNINNFINMIYFLCGKLKFDYPLYFT
>NC_016112.1|WP_014147473.1|1117885_1118323_-|transposase
MLLPLCIDDYVSQNNPVRAIDAYVDTLELYALGFKNTEPVIGAGQPAYGPAALLKLYLYDYLQGISSSRKLDERPPAITPVRGEFSLMMLTYNLTRLLTIPGADTLRDYYAQIPGNILKNVEIWIKDDGFLLVSLNKNDAIGSKT
>NC_016112.1|WP_014147474.1|1118408_1119071_-|Fe2+-dependent-dioxygenase
MDSVFVIKDILTTEQVASICNNLKQVEFDDGKVTAAGMAKAVKNNQQVMVDKVPDLMPLLSKVIMANPLFNAVTMPRAIVNVMLSRYQPGMEYGTHTDSAIMPGGNRADISFTLFLSSPDAYEGGDLVLETALGEQRIRLNAGSLILYPTGELHRVSPVTRGERIVIVGWIQSRIRDSRKRQILLDLDSARKQYLEKVGHDRTVDIMLKTSMNLRRMWDE
>NC_016112.1|WP_162472919.1|1120863_1121895_+|hypothetical-protein
MAVDLLPDDAISPLGLHLTLVSNSWATIGDWPPSLPLAESDGLFDERAVECSTMVFSGSMAPDDAASGATGQEAVTYTLHKIDHVMLSSDMPWLRLLHSAGKSQSPACAKLTSLPSGEASLPLADALRQTLLDWLYSQQLTYREGLVNWIATGPIGHFGSVETRVLERTGQADLQVDVTCLAQVRQANNPDIPETCLTLYGERLGTWLLHRNQPKVTKVVNKESQQLLVNEHQEVLIADRLEDLIQQTGLGPLEKRLFKQAKLLPPERLWHTPSLETNQTPEHTCVKRQPEEATLNLSGLDARSRSSLTQLFKWAQQGQLTYLNLDLLYKVARQLSKANRSSF
>NC_016112.1|WP_014147478.1|1123469_1123970_-|flagellar-protein-FlgN
MSLISQTFPIAEKLIANGLSLTEQLYQALQQESTTLKQSALTETLDEITRQKQPLAQELNLFAKQLAQILETEKLPNTPAGLSDYLERAIQAGFDTSKTAENWTTLIKTTEKCQLLNEQNGASVEILLRHTRQSLNILKGKPQTTNTYGPDGNTKSDLFSGTLFSV
>NC_016112.1|WP_014147479.1|1123966_1124275_-|flagellar-biosynthesis-anti-sigma-factor-FlgM
MAIDPIASRIPSATTTKSPAKPGIETGAAKVQAKPNNDRIEITANSGQIKRALDTAASLPVVDNERVASIKQALAEGTYAIDPERIAQKISQFELLSTEDSP

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Crispr_ID: NC_016112_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016112_2

1516465-1519654

TypeI

I-C

Consensus_repeat	Method
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	PILER-CR
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CRISPRCasFinder
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CRT

44 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3,WYL

The CRISPR arrays of NC_016112_2

>merge|NC_016112|2|1516465-1519654|PILER-CR,CRISPRCasFinder,CRT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGAAAATATAAAGCCTAAACTGCTGGCCCTATCGGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATGACAACTCAAACAGCAAATCAAGTAAAACCGCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTTTTATCGCCACGCCCAGTTGCGGAGGACACGGAGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCCAATTTCCCTGCGCCATGTATGAAATTGAAAATGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTCACCTAACCAATGCGACATCGTTCGAAGAATCGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAAAGTATCAGCATGAGCGCCCCCGGAAGCGAGAAGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATGCCATCGACGATGCCGGGGAGGTTACGCATTTTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGTGCCAATTTTGACAATTTTGTGCATCAAGCGGTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTAGTTAGTGGCGTTGTGAGTTACTGAAATGGAGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATTCAAAAGCCTGTGCGAGCTGCCGGAATTCGAACGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATAGTTCGCGGTTTTGGTTTGAAAATGAACGGGCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCTTGGATTGGCATGATTTGTCCTATTGCATTGTTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGTCCATGACCTGGCTTTCTACGAATACGATGTTCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCTTTCCATGGGTTGCCTTGAGGATCGATTCCGTTTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAGGCTGGAAGTCGAAGTATTGAGAGAAAAGACCGGTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACCTGTTGTCGTGTAGCGTCAGGCATCGCTGCATTGTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACGCGGGGAATTTTGAATCTTTGTGCGCGTTTTCCAGGTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACCTGTTGTCGTGTAGCGTCCGTTCATCGCTGCATTGTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACGCGGGGAATTTTGAATCTTTGTGCGCGTTTTCCAGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATTCGTGGCTTGCATAGAGTTGGCACGGAATCAAGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCGAAAAGTTGCCGGATTGATAGCTGTAGCGCTTCTGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATTTACAAGATTTCATCGTAGTTAAAGGCATTTGTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAATAAATCGAGCTGGGCGAACTGCCCGATTGCCTGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCCCAGGGATGCGGACTAGATTTAACTATCTAATTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCACCGATCGTCCCCTCTCCGCGCGCGTGGATGATCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACACACCATGCCGATTGTGTGTTATTACATTGAAGAGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTTCTAACAGCGGTTCATAAATATTTTCAGAAACAGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATCAATATTTCTGCTAGATTTTAATCTGTGTGGCTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGATCCGGCACCGTCACGCATTTGCAACAGCGTATCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGCTGGTGATATCCGGGCGTTTGTCCGGAGCGTTGCTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAACCTTAAAGCCTGCGCGGCGACTGAGCGCATCAAAGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAGGTGAAGGAGGCTGAAGATGCCAGGGTTTATGAGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGAATATACGGATCCGCTCACTTTCGAGCAGAAATCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGGCAATGTTGGCGTCGGTCAGCACCGAGTCGATGCGTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGTGTCGGACCCGTTCAATGCCGACGTATTGCCGCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTTTCGCGGACCGTCGACAGCGCCGCAATCTACGCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTAAGTATCGTCGGCGTTTTGATTGATAAAATATCGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAAATCGGGGCGACGTATTATTTCGCGTTTGAAGCGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACACCTCGCCCAGCAACGCGACGGTCTATTTCGAGGGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATTTCAACCCTCCAGCTTAAAGCGTAAAAATACCGTGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCTTCCGGTTTTTGCACGATATGCGCTAACCAATGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAATAAAGGCGATACGAACGAAAACCGGCCAGCGGCGGGGGGAGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAAGCGCGTTCGGCGAGGCCGCCGGCAGTATCCTGGGTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCAGGTGGTCAGGCGCGGATTGACGGCAGCGCGGAGTATCTCCCGGCCAAACAACCGGAAAAATATAGTTAA

>NC_016112|2|1|1516465-1519583|PILER-CR
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GAAAATATAAAGCCTAAACTGCTGGCCCTATCGG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATGACAACTCAAACAGCAAATCAAGTAAAACCGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TTTTATCGCCACGCCCAGTTGCGGAGGACACGGA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CCAATTTCCCTGCGCCATGTATGAAATTGAAAAT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TCACCTAACCAATGCGACATCGTTCGAAGAATCG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AAAGTATCAGCATGAGCGCCCCCGGAAGCGAGAA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATGCCATCGACGATGCCGGGGAGGTTACGCATTTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GTGCCAATTTTGACAATTTTGTGCATCAAGCGGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TAGTTAGTGGCGTTGTGAGTTACTGAAATGGAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTCAAAAGCCTGTGCGAGCTGCCGGAATTCGAAC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATAGTTCGCGGTTTTGGTTTGAAAATGAACGGGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CTTGGATTGGCATGATTTGTCCTATTGCATTGTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GTCCATGACCTGGCTTTCTACGAATACGATGTTC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CTTTCCATGGGTTGCCTTGAGGATCGATTCCGTTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AGGCTGGAAGTCGAAGTATTGAGAGAAAAGACCG
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACC	TGTTGTCGTGTAGCGTCAGGCATCGCTGCATTG
TATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACGC	GGGGAATTTTGAATCTTTGTGCGCGTTTTCCAGGT
ATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACCTG	TTGTCGTGTAGCGTCCGTTCATCGCTGCATTGTA
TCTCCCGGCCAAACAGCCGGAGCGGATTGAAACGCGG	GGAATTTTGAATCTTTGTGCGCGTTTTCCAGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATTC	GTGGCTTGCATAGAGTTGGCACGGAATCAAGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCGAA	AAGTTGCCGGATTGATAGCTGTAGCGCTTCTGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATTT	ACAAGATTTCATCGTAGTTAAAGGCATTTGTGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAATA	AATCGAGCTGGGCGAACTGCCCGATTGCCTGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCCCA	GGGATGCGGACTAGATTTAACTATCTAATTGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCACC	GATCGTCCCCTCTCCGCGCGCGTGGATGATCGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACACAC	CATGCCGATTGTGTGTTATTACATTGAAGAGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTTCT	AACAGCGGTTCATAAATATTTTCAGAAACAGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATCA	ATATTTCTGCTAGATTTTAATCTGTGTGGCTGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGATC	CGGCACCGTCACGCATTTGCAACAGCGTATCGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGCTG	GTGATATCCGGGCGTTTGTCCGGAGCGTTGCTGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAACC	TTAAAGCCTGCGCGGCGACTGAGCGCATCAAAGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAGGT	GAAGGAGGCTGAAGATGCCAGGGTTTATGAGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGAAT	ATACGGATCCGCTCACTTTCGAGCAGAAATCGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGGCA	ATGTTGGCGTCGGTCAGCACCGAGTCGATGCGTGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACGTGT	CGGACCCGTTCAATGCCGACGTATTGCCGCGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTTTC	GCGGACCGTCGACAGCGCCGCAATCTACGCGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACTAAG	TATCGTCGGCGTTTTGATTGATAAAATATCGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAAAT	CGGGGCGACGTATTATTTCGCGTTTGAAGCGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACACCT	CGCCCAGCAACGCGACGGTCTATTTCGAGGGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACATTT	CAACCCTCCAGCTTAAAGCGTAAAAATACCGTGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACCTTC	CGGTTTTTGCACGATATGCGCTAACCAATGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAATA	AAGGCGATACGAACGAAAACCGGCCAGCGGCGGGGGGAGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAACAAGC	GCGTTCGGCGAGGCCGCCGGCAGTATCCTGGGTAT
CTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC

>NC_016112|2|2|1516465-1519654|CRISPRCasFinder
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GAAAATATAAAGCCTAAACTGCTGGCCCTATCGG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATGACAACTCAAACAGCAAATCAAGTAAAACCGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TTTTATCGCCACGCCCAGTTGCGGAGGACACGGA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CCAATTTCCCTGCGCCATGTATGAAATTGAAAAT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TCACCTAACCAATGCGACATCGTTCGAAGAATCG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AAAGTATCAGCATGAGCGCCCCCGGAAGCGAGAA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATGCCATCGACGATGCCGGGGAGGTTACGCATTTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GTGCCAATTTTGACAATTTTGTGCATCAAGCGGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TAGTTAGTGGCGTTGTGAGTTACTGAAATGGAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTCAAAAGCCTGTGCGAGCTGCCGGAATTCGAAC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATAGTTCGCGGTTTTGGTTTGAAAATGAACGGGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CTTGGATTGGCATGATTTGTCCTATTGCATTGTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GTCCATGACCTGGCTTTCTACGAATACGATGTTC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CTTTCCATGGGTTGCCTTGAGGATCGATTCCGTTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AGGCTGGAAGTCGAAGTATTGAGAGAAAAGACCG
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACC	TGTTGTCGTGTAGCGTCAGGCATCGCTGCATT
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACG	CGGGGAATTTTGAATCTTTGTGCGCGTTTTCCAG
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACC	TGTTGTCGTGTAGCGTCCGTTCATCGCTGCATT
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACG	CGGGGAATTTTGAATCTTTGTGCGCGTTTTCCAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTCGTGGCTTGCATAGAGTTGGCACGGAATCAAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CGAAAAGTTGCCGGATTGATAGCTGTAGCGCTTCTG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTTACAAGATTTCATCGTAGTTAAAGGCATTTGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AATAAATCGAGCTGGGCGAACTGCCCGATTGCCTG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CCCAGGGATGCGGACTAGATTTAACTATCTAATT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CACCGATCGTCCCCTCTCCGCGCGCGTGGATGATC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ACACCATGCCGATTGTGTGTTATTACATTGAAGA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TTCTAACAGCGGTTCATAAATATTTTCAGAAACAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATCAATATTTCTGCTAGATTTTAATCTGTGTGGCT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GATCCGGCACCGTCACGCATTTGCAACAGCGTATC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GCTGGTGATATCCGGGCGTTTGTCCGGAGCGTTGCT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AACCTTAAAGCCTGCGCGGCGACTGAGCGCATCAAA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AGGTGAAGGAGGCTGAAGATGCCAGGGTTTATGA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GAATATACGGATCCGCTCACTTTCGAGCAGAAATC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GGCAATGTTGGCGTCGGTCAGCACCGAGTCGATGCGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GTGTCGGACCCGTTCAATGCCGACGTATTGCCGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TTTCGCGGACCGTCGACAGCGCCGCAATCTACGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TAAGTATCGTCGGCGTTTTGATTGATAAAATATC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AAATCGGGGCGACGTATTATTTCGCGTTTGAAGCG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ACCTCGCCCAGCAACGCGACGGTCTATTTCGAGGG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTTCAACCCTCCAGCTTAAAGCGTAAAAATACCGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CTTCCGGTTTTTGCACGATATGCGCTAACCAAT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AATAAAGGCGATACGAACGAAAACCGGCCAGCGGCGGGGGGAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AAGCGCGTTCGGCGAGGCCGCCGGCAGTATCCTGG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CAGGTGGTCAGGCGCGGATTGACGGCAGCGCGGA
GTATCTCCCGGCCAAACAACCGGAAAAATATAGTTAA

>NC_016112|2|1|1516465-1519654|CRT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GAAAATATAAAGCCTAAACTGCTGGCCCTATCGG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATGACAACTCAAACAGCAAATCAAGTAAAACCGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TTTTATCGCCACGCCCAGTTGCGGAGGACACGGA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CCAATTTCCCTGCGCCATGTATGAAATTGAAAAT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TCACCTAACCAATGCGACATCGTTCGAAGAATCG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AAAGTATCAGCATGAGCGCCCCCGGAAGCGAGAA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATGCCATCGACGATGCCGGGGAGGTTACGCATTTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GTGCCAATTTTGACAATTTTGTGCATCAAGCGGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TAGTTAGTGGCGTTGTGAGTTACTGAAATGGAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTCAAAAGCCTGTGCGAGCTGCCGGAATTCGAAC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATAGTTCGCGGTTTTGGTTTGAAAATGAACGGGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CTTGGATTGGCATGATTTGTCCTATTGCATTGTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GTCCATGACCTGGCTTTCTACGAATACGATGTTC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CTTTCCATGGGTTGCCTTGAGGATCGATTCCGTTT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AGGCTGGAAGTCGAAGTATTGAGAGAAAAGACCG
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACC	TGTTGTCGTGTAGCGTCAGGCATCGCTGCATT
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACG	CGGGGAATTTTGAATCTTTGTGCGCGTTTTCCAG
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACC	TGTTGTCGTGTAGCGTCCGTTCATCGCTGCATT
GTATCTCCCGGCCAAACAGCCGGAGCGGATTGAAACG	CGGGGAATTTTGAATCTTTGTGCGCGTTTTCCAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTCGTGGCTTGCATAGAGTTGGCACGGAATCAAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CGAAAAGTTGCCGGATTGATAGCTGTAGCGCTTCTG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTTACAAGATTTCATCGTAGTTAAAGGCATTTGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AATAAATCGAGCTGGGCGAACTGCCCGATTGCCTG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CCCAGGGATGCGGACTAGATTTAACTATCTAATT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CACCGATCGTCCCCTCTCCGCGCGCGTGGATGATC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ACACCATGCCGATTGTGTGTTATTACATTGAAGA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TTCTAACAGCGGTTCATAAATATTTTCAGAAACAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATCAATATTTCTGCTAGATTTTAATCTGTGTGGCT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GATCCGGCACCGTCACGCATTTGCAACAGCGTATC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GCTGGTGATATCCGGGCGTTTGTCCGGAGCGTTGCT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AACCTTAAAGCCTGCGCGGCGACTGAGCGCATCAAA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AGGTGAAGGAGGCTGAAGATGCCAGGGTTTATGA
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GAATATACGGATCCGCTCACTTTCGAGCAGAAATC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GGCAATGTTGGCGTCGGTCAGCACCGAGTCGATGCGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	GTGTCGGACCCGTTCAATGCCGACGTATTGCCGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TTTCGCGGACCGTCGACAGCGCCGCAATCTACGC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	TAAGTATCGTCGGCGTTTTGATTGATAAAATATC
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AAATCGGGGCGACGTATTATTTCGCGTTTGAAGCG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ACCTCGCCCAGCAACGCGACGGTCTATTTCGAGGG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	ATTTCAACCCTCCAGCTTAAAGCGTAAAAATACCGT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CTTCCGGTTTTTGCACGATATGCGCTAACCAAT
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AATAAAGGCGATACGAACGAAAACCGGCCAGCGGCGGGGGGAG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	AAGCGCGTTCGGCGAGGCCGCCGGCAGTATCCTGG
GTATCTCCCGGCCAAACAGCCGGGAGCGGATTGAAAC	CAGGTGGTCAGGCGCGGATTGACGGCAGCGCGGA
GTATCTCCCGGCCAAACAACCGGAAAAATATAGTTAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_016112.1\|WP_014147831.1\|1508367_1510671_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_016112.1\|WP_014147848.1\|1531288_1533109_-\|phosphogluconate-dehydratase	unknown	unknown	gnl\|CDD\|181628
NC_016112.1\|WP_014147830.1\|1507402_1508269_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NC_016112.1\|WP_014147838.1\|1519919_1520933_+\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|182341
NC_016112.1\|WP_046061418.1\|1510822_1511491_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NC_016112.1\|WP_014147841.1\|1521716_1522301_-\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|187714
NC_016112.1\|WP_014147842.1\|1522485_1523925_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|180579
NC_016112.1\|WP_014147847.1\|1530582_1531233_-\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl\|CDD\|235577
NC_016112.1\|WP_014147836.1\|1514946_1515981_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_016112.1\|WP_014147828.1\|1505473_1506340_+\|RNA-polymerase-sigma-factor-RpoH	unknown	unknown	gnl\|CDD\|235838
NC_016112.1\|WP_014147843.1\|1524025_1525339_-\|dihydrolipoyllysine-residue-acetyltransferase	unknown	unknown	gnl\|CDD\|237000
NC_016112.1\|WP_014147849.1\|1533656_1534151_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|223119
NC_016112.1\|WP_014147829.1\|1506784_1507357_-\|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl\|CDD\|377025
NC_016112.1\|WP_014147840.1\|1521169_1521373_-\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014147837.1\|1515993_1516284_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_016112.1\|WP_014147844.1\|1525355_1528034_-\|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	unknown	unknown	gnl\|CDD\|236500
NC_016112.1\|WP_014147835.1\|1514293_1514950_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_016112.1\|WP_014147834.1\|1513246_1514194_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
NC_016112.1\|WP_014147845.1\|1528449_1529748_-\|citrate-(Si)-synthase	unknown	unknown	gnl\|CDD\|180164
NC_016112.1\|WP_014147833.1\|1511480_1513247_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245

Protein	Function_ID	Function_description	E-value
NC_016112.1\|WP_014147831.1\|1508367_1510671_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.27039e-50
NC_016112.1\|WP_014147848.1\|1531288_1533109_-\|phosphogluconate-dehydratase	gnl\|CDD\|181628	PRK09054, PRK09054, phosphogluconate dehydratase; Validated.	0
NC_016112.1\|WP_014147830.1\|1507402_1508269_-\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	4.32589e-12
NC_016112.1\|WP_014147838.1\|1519919_1520933_+\|L,D-transpeptidase-family-protein	gnl\|CDD\|182341	PRK10260, PRK10260, L,D-transpeptidase; Provisional.	1.61531e-52
NC_016112.1\|WP_046061418.1\|1510822_1511491_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.725e-53
NC_016112.1\|WP_014147841.1\|1521716_1522301_-\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|187714	cd08645, FMT_core_GART, Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART). Phosphoribosylglycinamide formyltransferase, also known as GAR transformylase or GART, is an essential enzyme that catalyzes the third step in de novo purine biosynthesis. This enzyme uses formyl tetrahydrofolate as a formyl group donor to produce 5'-phosphoribosyl-N-formylglycinamide. In prokaryotes, GART is a single domain protein but in most eukaryotes it is the C-terminal portion of a large multifunctional protein which also contains GAR synthetase and aminoimidazole ribonucleotide synthetase activities.	3.47428e-74
NC_016112.1\|WP_014147842.1\|1522485_1523925_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|180579	PRK06467, PRK06467, dihydrolipoamide dehydrogenase; Reviewed.	0
NC_016112.1\|WP_014147847.1\|1530582_1531233_-\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl\|CDD\|235577	PRK05718, PRK05718, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional.	9.24367e-114
NC_016112.1\|WP_014147836.1\|1514946_1515981_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NC_016112.1\|WP_014147828.1\|1505473_1506340_+\|RNA-polymerase-sigma-factor-RpoH	gnl\|CDD\|235838	PRK06596, PRK06596, RNA polymerase factor sigma-32; Reviewed.	5.73806e-166
NC_016112.1\|WP_014147843.1\|1524025_1525339_-\|dihydrolipoyllysine-residue-acetyltransferase	gnl\|CDD\|237000	PRK11855, PRK11855, dihydrolipoamide acetyltransferase; Reviewed.	0
NC_016112.1\|WP_014147849.1\|1533656_1534151_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|223119	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism].	1.62515e-85
NC_016112.1\|WP_014147829.1\|1506784_1507357_-\|DNA-3-methyladenine-glycosylase-I	gnl\|CDD\|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	3.55652e-129
NC_016112.1\|WP_014147837.1\|1515993_1516284_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.20032e-27
NC_016112.1\|WP_014147844.1\|1525355_1528034_-\|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	gnl\|CDD\|236500	PRK09405, aceE, pyruvate dehydrogenase subunit E1; Reviewed.	0
NC_016112.1\|WP_014147835.1\|1514293_1514950_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.57708e-43
NC_016112.1\|WP_014147834.1\|1513246_1514194_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	6.16524e-138
NC_016112.1\|WP_014147845.1\|1528449_1529748_-\|citrate-(Si)-synthase	gnl\|CDD\|180164	PRK05614, gltA, citrate synthase.	0
NC_016112.1\|WP_014147833.1\|1511480_1513247_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	2.18308e-85

>NC_016112.1|WP_014147837.1|1515993_1516284_+|CRISPR-associated-endonuclease-Cas2
MLVLITYDVSTETSEGRRRLRRVAKTCLNYGQRVQKSVFECRVNTMEMKRLKDQLLDIIDLEEDSLRFYRIIEPLEKNREEFGNSKAIDFENTLIV
>NC_016112.1|WP_014147836.1|1514946_1515981_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKQALNTLYVTTPEAYLRLEGETVCVMIEKQKKMQVPLHHLGAFVLFDNVMLSPALLGRCAEDGLSVVWLNRSGRFRARLEGPVNGNVLLRQAQYRAADDRDKSIKLAKRFIAGKIRNSRQILMRGARENKSEAEKSNLVHASRLLAGNLKKLPTVQTHDELRGVEGDSARIYFDALPKIIKPSARETFNFTTRNRRPPRDPFNALASFLYALVLSDCRSALETVGLDPQLGFLHAVRPGRQSLALDMLEEFRAPLCDRLALTLINREQLNAKDFDKREGGSVLLNDKGRKTVIGAFQTRKQEELNHPVLDQSLPIGLLAQIQARLLARFLREDSEDYIPYLQR
>NC_016112.1|WP_014147835.1|1514293_1514950_+|CRISPR-associated-protein-Cas4
MVNNIADSIEKIPLSALNQYVYCPRRCYLIHAEGEFTDNVHTESGSREHERVDTLLHEIKQDVRIEFALPVWSDRLGLTGRCDVVEFRSDGIVYPVEYKHGKRKKWLNDDLQLTAQALCLEEMLNVSVSFGAIYHIQSRRRREVEIDSDLRKTTESLIIEIRSLLDQSRCPSPIADKKRCPDCSLNSLCQPELINEIRRIKYWSDQLFDVSEEEWDSL
>NC_016112.1|WP_014147834.1|1513246_1514194_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MNIENRYEFLFLFDCENGNPNGDPDAGNAPRIDPEDMYGLVSDVALKRRVRNYVQIARHNMRPHAIFIEHATNLNRPIAESHLEANGEIPEKGKASKDKVRLAKEWMCKNFYDVRTFGAVMSTGANAGQVRGPVQFSFARSLDKVLPLDISVTRMAVAEDVKGAKDIASYKAWEDAQPEDQLRTMGRKSLIPYGLYAAKGFISANLAQETGFSEADLELLWEALLNMYDHDRSASKGMMSCRGLYIFKHTGTDSDLEQRKKQAMLGCAPAHKLLDLGGIIDIKKREGIETPRKFADYEVTVNKDRLPDGIELIAK
>NC_016112.1|WP_014147833.1|1511480_1513247_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLNEVLAHAERAGIKTEPGFSVKSAKWAIVIGKQAEITGLIPLGDGKTGLEFACCPDLSQSEMITGSLTRSQFLLESLAVVALYYKESTDEKEVDKYRSKHEYFVGLLEQASANCYELARAATALNNPEELQKLTRFLNNYQPKPKPTDSATLLIEDSFPLCSTAWHDWWRNQRASGNINDFDKAENKESMRCLLTGNAIVPVDTHPKIKGLSSVGGLGTGDVFIGFDKEAFQSYGLNKSANAATDEITAKIYAETFNQLIHRQSIRLINGLAVYWFGRELANRDDDLFAELENPAEPLSGQPTKPKQLLNAIKDGQRPDLLENYYYVMTVSGQSGRVMVRDWQQGRLIEMLENVNAWFDDLQIIARDGGKLAPPPKFLAVVGSLFRELKDAPAPLINDLWRTALNKNKPVSNSAFAQALMATRKAVINEEAQNHARMGLLKAYHIRNKGDRYMNTQLNPGHPSPAYQCGRLLAVLADLQYAALGDVGAGVVQRYYTATSQAPALRIGQLMSNAKNHLNKVGGGLAFEFENRIGEIMSAMTQIPKTLDLEQQSLFALGYYQQLADNRARMAENKAKKQAKLNQAEGEN
>NC_016112.1|WP_046061418.1|1510822_1511491_+|type-I-C-CRISPR-associated-protein-Cas5
MKVERYSYPIITPSAARGIFDAIYFKKEYDFYWQIERIELLKPPKYIALRRNEVKDKISASEVQKWMKGTKAITPLWADGTRDELGTDQKGRTQRQTMALKNVRYRLHARIQSRDTKANLNAMNAQFERRASQGKCFYQPYFGCREFPAFFELVQNNPETKPVDLDLDLGWMLYDVFDLSRSNDSQAKPAISVFHAELKSGVMRVPDYESEAVRKTEHDNVE
>NC_016112.1|WP_014147831.1|1508367_1510671_+|CRISPR-associated-helicase-Cas3'
MKKYFAHSGNDFGSWHLLNEHLESVSKLAHSYSEGWRGGEEAALAGLLHDLGKYGDRFQNRLHGQDQGLDHWSQGAFLALTKYGSIVSAIAIQGHHIGLQSLQKEDLKKLMPGNLAKHHPQHLQLSDLDIERLESRLHQDELTAQKPASRLFSGWLGQSQARIDTMLDVRRVFSALVDADFIDTESHFNGDANGKIYRKPGLKLNDDGIASAALKKLCDYIDAKSALADQASVLQQVRRQLLNCCLTNAQKSTSIFTLTAPTGSGKTLSMLSFALQHAIHNNLERIILVIPYLSIIEQTAQIYREIFAEFGPDFVLEHHSMSGLGEETAQSDAEGCEDRERQLRRQRLLSENWDAPVVVTTSVQFLESLFSNRPSACRKIHRIANSVILFDEVQTLPTDLAIPTLAALSHIGHSWQSSVVFATATQPAFDHLHAAVQKQCAFGWQPTILVNEHGSMSNALRRVDYDWLDENPTWTELAAMLNEQTQVLCIVNLKRHTQALWEAFETTDELFHLSTNLCPLHRQQVLNEVRQRLKDDLPCRLIATQCIEAGVDVDFPLVYRAFGPLDAIIQAAGRCNREGKLNKGKIVVFTPDCDGRLYPDKTYEQASSVTASLKHDYGEAFDPYDSKIIEQYYRRLYTVAAPEQLGKRLNEAVQDLNFVDVAKHYRLINNDTINLVVPYDRELYEKLREQAATEGLTSKWVKQARCLSISLFRPKPDDVIWDSLVPVQVFRNGRHSRQEDWFIVNNLEDYDANLGYIKPEHLNLYIA
>NC_016112.1|WP_014147830.1|1507402_1508269_-|WYL-domain-containing-protein
MGNLLQPNLKWEQRHRLTLLEATVFWSGEISTGTLINYFGISRVQASKDLTLYQSLCPGNIRYDKYLKRYVVDDSFKPGFMDGTTGELLQVLKLQQQNGYETLIALVGNLPTVEIVNPLARQIDTRVLRGIVQAVRFKFELEISYQSLSSPEPKTLQINPHTLVFDGLRWHVRSFSVTHNDYRDFVLARIHRVSILGKADEPSFTDTLWNKWLTVEIGPHPGLNDAQKSVIERDFGMVDGKCVTQIRAALLSYFLLSMRIGKDDLHREAMEQQIVLLNRDEIKDFIFF
>NC_016112.1|WP_014147829.1|1506784_1507357_-|DNA-3-methyladenine-glycosylase-I
MNKCRWALSSPLEEDYHDREWGVPVHDDRLLFEFLVLEGAQAGLSWSTILKKRDHFRAAFDNFDPVSVAGYDEAKISELLENPGIIRNRLKVNAAVTNARAFLNVKEEAGSFDAFLWDFVDGRPIQHAWRTHAELPANTPLSDRLSKELKIRGFKFVGSTICYAFMQAVGMVNDHTVDCFRYGEIARISD
>NC_016112.1|WP_014147828.1|1505473_1506340_+|RNA-polymerase-sigma-factor-RpoH
MSNALAFALPTNLSVGTFDTYLNAVAQTPTLSHEQERKLALRYRDEGDLEAAKELVMSNLRFVVHVARGYSGYGLPLPDIIQEGNVGLMKAVKRFDPDVGVRLVTFAVHWIRAEIHEYVIKNWRIVKIATTKAQRKLFFNLRKSKNNLGWLSHDEAKAVANDLGVDLKTVYEMEKRMDSSDMAFDMPHDEPSEESTYAFPVSYLEQHNSDPADLLENEQWQGYEENMLSEAMAELDERSLDILNSRWLSEEKATLHDLAARYNVSAERIRQLEKNAMNKLKAAFVLEA
>NC_016112.1|WP_014147838.1|1519919_1520933_+|L,D-transpeptidase-family-protein
MNTRVLFALLVVGFLGSAHAVTYSWPEDPNDNVVTEHADDFPFTRTNQDETLLDIARRFSLGQVEIVRLNQDVDRWSVKQDEVVRLPNRRVLPDTPHEGIVLNIAEYRMYYYPPAQAGMPRTVMSFAHGVGRQDWQTPLGLTKVVKKVKDPSWYPPESIRREHAAMGDPLPTVVPPGPHNPLGAYALHLALKGEYRIHGTDVDKIYGIGMQITHGCVRMYPEDIEQLYHSVSVGTPVRIVQQQIKMGWLDNQLYIEAHPDLEGVETTFEQRLDTAMQLIAKANNGVIPELNEAVLIKALTVLDGDPVPIFERLPDMPDFEEEIGLREAAVESTYRLQ
>NC_016112.1|WP_014147840.1|1521169_1521373_-|hypothetical-protein
MYVFPEMGRIIIVALMIVIPAMLIYRKAGFHPAWALLVFLPGFGLLLIFLQLALLPWPNQKTNDRSS
>NC_016112.1|WP_014147841.1|1521716_1522301_-|phosphoribosylglycinamide-formyltransferase
MKISFLASHGGSSARKIIETIEQGGLPGFEIGILITNNKDSAIYDWCLTHGIEVFHISSKTHSDNEDQAIKKALQSAGTELIVLSGYMKKIGPQTLSAYSGKILNIHPSLLPKFGGRGMYGDFVHAAVLEAGETVSGATVHFVTDAYDEGPLLLQKEVPVLSGDTVESLGQRVRAIEGDLYINALKRLLTTTDI
>NC_016112.1|WP_014147842.1|1522485_1523925_-|dihydrolipoyl-dehydrogenase
MTANAAANESNLHAEVLVLGGGPGGYTAAFRAADLGKQVVIVERYPVLGGVCLNVGCIPSKALLHMAQIVHEAQEFSGHGVDFGAPKFDLDKIRSWKDSVTKGLNNGLDGLVKQRKITRIQGNGSFVSENQLQVDNENGTQLISFDQAIIAAGSEPTKIPAFPNDDPRLWDSTGALQLREIPEKLLIVGGGIIGLEMATVYHALGSKISVVELMDQIIPGCDKDLVRPLHNRIKKQYEAIWTETRVTAIEALEEGLKVSFEGDKAPESEIFDAVLVAVGRRPNGKKLGAENAGIQVTEQGFIEVDKQQRTNIPHIYAIGDIVGNPMLAHKAAYEGKIAAEVIAGHKAAFDALTIPSVAYTDPEIAWMGLTENQAKEQGIEIDKGVFPWAASGRSLSMGRSEGMTKVICDKETGRILGAGIVGPHAGDLIAEAVLALEMGADAEDVALTIHPHPTLSETFAFASEVVAGTITDLYLGKKR
>NC_016112.1|WP_014147843.1|1524025_1525339_-|dihydrolipoyllysine-residue-acetyltransferase
MSELIEIKVPDLGGSSEVDVVEILVQPGDTIEIEQPLVVLETDKATMDMPSTIAGTIRELKIKVGDKVSQGVTIATVEASEPSEPEQKPPVSEPEPATEATDKQDKPIEEKPAESAASAPAASPAPTPAATIDTELSGQHLPHATPAIRLFARELGVDLSLIRQGSGRKGRILKEDVKAYVKQTLSEGVKSSGAGIPPIPAVDFTQFGETEVLPLSKIKRLTGQNMTRVWLNLPLVTHHDEADITELEAFRKQINAENSQNGKVTGLIFIIKALANALKQFPNFNASLSPDGESLILKKYCHIGIAVDTPNGLVVPVLRDVDRKSIYELSAELATLSEKARAGKLMPNEMQGGSMTISSLGGIGGTAFTPIVNAPEVAILGVTRAKMQPVWDGKEFQPRLMLPLDMTYDHRVIDGAEAARFMVKLTDFLTDIRRLIL
>NC_016112.1|WP_014147844.1|1525355_1528034_-|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type
MKNNKSPAVVEQEDVDPIETQEWIDALKAVMEIEGETRAQFLIEKLVSVARQSGSDIPFSATTDYINTISVDQQIQFPGNTTIEQRIRSYVRWNAMMMVLRANRDTNVGGHIASFASAATLYDVGQNHFWRAPSEQHDGDLLFVQGHSAPGDYARAFLLDRLTEEQMDNFRQEVDGNGLSSYPHPWLMPEFWQFPTVSMGLGPIMAIYQARFMRYLKDRSLADTSNRKVWCFLGDGETDEPESLGEIGMAGREKLDNLIFVVNCNLQRLDGPVRGNGKIIQELEGTFRGAGWNVIKLVWGRHWDKLLARDHQGLLVKRMTECVDGDYQTFKAKDGAYVREHFFNTPELKAMVADLSDLDIWLLNRGGHDPAKIYAAFHAAVNHKGQPTVVLAKTIKGYSMGESGEGQNTSHQQKKMSINSLTRFRDRYELPVTNEQIQELPYLKFPEDSKELAYMKERRAELGGYLPNRRAKSYALNVPVLSDFKSLLQATGEGREISTTMAFVKMLNILVKDKNIGKRIVPIVPDESRTFGMEGMFRQLGIWSQVGQLYTPQDADQLMFYKEDKNGQVLQEGINEAGGMCDWIAAGTSYSTHNVPMIPFFIFYSMFGFQRVADLIWAAADQRTRGFLLGGTAGRTTLNGEGLQHEDGHSHIFAGTVPNCISYDPTFSYEIAVIIQDGLRRMYVDQEDIFYYITVMNENYEHPAMPKGIEESILKGMYSFKKGDGRAKTRVQLLGSGTIFREAIAAAELLQNDWNVTADLWSCTSFTELARDGHSCERWNRLHPTETPKKPHVTECLENAKGPIIAATDYVRLYAEQIRPYLSAPYTVLGTDGFGRSDTREALRRFFEVNRYHIAVAALKSLADIGEFELAKVETAIAKYGINPETVAPWRL
>NC_016112.1|WP_014147845.1|1528449_1529748_-|citrate-(Si)-synthase
MTNHNQVTIRNEDDRISCDLPVLQGTIGPDVIDIRTLYRDTGVFTYDPGFTSTASCSSKITFIDGDKGILLYRGYPIEQLAEKCDFMEVCYLLLHDELPNGRQMQEFVNDITYHTMVHDQLTDFYKGFRRDAHPMATIVAVVGALSAFYHHELDIRCPIDRNLSAIRLIAKMPTIVAMSHKYSSGMPFMYPQNKLGYVENFMYMMHATPCEDYVQNPILVRAMDRILILHADHEQNASTSTVRLAGSSGANPYACITSGIACLWGAAHGGANEAVLRMLLEIGDVSRIGEFIDKAKDKNDPFRLMGFGHRVYKNYDPRAKLMRETCHEVLNELGLHDDPLFKLALELERIALEDEYFIEKKLYPNVDFYSGIVMRALGIPTVMFTAIFAMARSIGWIAHWDEMISDDEQKIGRPRQLYKGHTQRDVVSISAR
>NC_016112.1|WP_014147847.1|1530582_1531233_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MTQNNWKLHPSAVLNAGPVMPVMVIKNIEDAVPLAQALIEGGIKVLEITLRTPVALDAIKLISEQVKDAIVGVGTVTTPEQLQAAENAGAVFAISPGLTPTLLKAATKSNIALIPGISTISELMLGMEYGLDHFKFFPAAAAGGVNMLKGIAGPIPSVTFCPTGGISASNYNEYLSLPNVACVGGSWLAPDDAVAAKDWPRITELAKTAIENAVKK
>NC_016112.1|WP_014147848.1|1531288_1533109_-|phosphogluconate-dehydratase
MHPILNSVTEEIIERSRESRALYLARVDSASKKGPHRSVLGCGNLAHGFAACAATEKADLAGDQKANVAIVSAYNDMLSAHEPYKDFPNLIKDAAKEAGGVAQFAGGVPAMCDGVTQGQPGMELSLFSRDVIAMSTAISLSHNMFDAALYLGVCDKIVPGLLIGALSFGHLPAIFVPAGPMTSGITNKEKARTRQKYAEGKIGRKELLESESKAYHGPGTCTFYGTANSNQMMVEIMGLHLPGSSFINPYTPLRDELTKAATKQVLKFTALGNDFRPIGHVVDEKAIVNAIVGLLATGGSTNHTMHLVAIARTAGIVINWDDFDNLSKVVPLIAKIYPNGPADVNHFQAAGGMGVLIGELLRNGLLHEDTITVADEQGMQHYTQEPKLIDGQLTWEPSPAASLDPEVLSTVEKPFAKSGGLHVMHGNLGRGISKVSAVKEEHQIVEAPAIVFDDQDDLMEAFKRGELEKDFIAVIRFQGPKSNGMPELHKLTPPLGLLQDKGFKVALVTDGRMSGASGKVPSAIHMCPECADGGPLAKVRNGDMIRLNAQTGEINVLVDNTEFNARRPAANHAKDHHHGMGRELFAGFRLNASSAETGATNVFIND
>NC_016112.1|WP_014147849.1|1533656_1534151_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MTVLVGIIMGSTSDWETMQFAAEKLEQFGIAHEVEVVSAHRTPDKLFAYADAAESRGLEVIIAGAGGAAHLPGMVAAKTAVPVLGVPIQSKALNGMDSLLSIVQMPAGIPVGTLAIGKAGAINAALLAAAIVGNKYPEYREAVRHFRQQQTDAVLANADPRSVE

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Crispr_ID: NC_016112_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016112_3

2435093-2437273

TypeI

I-C

Consensus_repeat	Method
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	PILER-CR
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CRISPRCasFinder
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CRT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	PILER-CR

33 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3,RT

The CRISPR arrays of NC_016112_3

>merge|NC_016112|3|2435093-2437273|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTTCAATCCACGCGCCCGCACGGGGCGCGACGTACTCGATGCCCAGTTTCGTGTTCGCGTCGGGGTTTCAATCCACGCGCCCGCACGGGGCGCGACCGCTGGAGCAATCGCAGCAATTGGGATGGCAGGTTTCAATCCACGCGCCCGCACGGGGCGCGACCAGTCGACTCCTTGCGTCGATGCTCCTGTGTCGTTTCAATCCACGCGCCCGCACGGGGCGCGACAGCGTTTCCTCGTTCTCTTGACCCGTATTTGCGTTTCAATCCACGCGCCCGCACGGGGCGCGACGTATCTCCTATGTATGGATACCCATCAGTCAGGTTTCAATCCACGCGCCCGCACGGGGCGCGACGATCGCCCTGTGATCTGTGTTAACGTCAAATTGTTTCAATCCACGCGCCCGCACGGGGCGCGACCAGCGATTCGGCGCGTGTCGCAGATGTCTTGACGTTTCAATCCACGCGCCCGCACGGGGCGCGACGTAATATAACTTCTACTGCTGTCAATTACGCTAGTTTCAATCCACGCGCCCGCACGGGGCGCGACGGCTACGACTGGCACATGATCGTCGACAACTGGGTTTCAATCCACGCGCCCGCACGGGGCGCGACTTCGGCGCTTGGCCGAAAAGCACGGTATTACAGTTTCAATCCACGCGCCCGCACGGGGGGCGCCGTTTGGATTAACGCCGTTTCGGCTTTTTTGTTTCAATCCACGCGCCCGCACGGGGCGCGACGCCGTGGTGTTCATATTTACTGCGGAGGATTTAGTTTCAATCCACGCGCCCGCACGGGGCGCGACGCGAGAGGATCCGATGTATCAGGCGGTATTGGTGTTTCAATCCACGCGCCCGCACGGGGCGCGACCAATGAACCGTTGCCGAAAAACGCATTGGCCAGTTTCAATCCACGCGCCCGCACGGGGCGCGACAAAATTGGGAGCAAGCAAAAGTGGTTGGATTCGTTTCAATCCACGCGCCCGCACGGGGCGCGACTTGACGCGCTTCGTCACGGGGTCAGCGCATTTGTTTCAATCCACGCGCCCGCACGGGGCGCGACTTGATGTCGAGGTTCTTTTTGTTGCGATCTAGGTTTCAATCCACGCGCCCGCACGGGGCGCGACCGAGAGCCGCCCGGATGCCAGCGCAAATTGGATTGTTTCAATCCACGCGCCCGCACGGGGCGCGACACGATTAAAGCTATCTATCGGATGGCGGTTGAGTTTCAATCCACGCGCCCGCACGGGGCGCGACGAACTGAGCTCAGAACAAACTTATTGGATAGCAGGTTGAGTTTCAATCCACGCGCCCGCACGGGGCGCGACCTGATTGTTTTGTTCTCATACCGATACGAAAAATTCGTTGTTTCAATCCACGCGCCCGCACGGGGCGCGACATTTTTGAATCCGACGCCTCGCTATTTTCCAGGTTTCAATCCACGCGCCCGCACGGGGCGCGACCACATGAACGCTGAAAACGCCCTATTGCAATACGTTTCAATCCACGCGCCCGCACGGGGCGCGACGCCCGCTAAGATTTCGACATTGCAGGGCGGTTGTTTCAATCCACGCGCCCGCACGGGGCGCGACATGAGCGATCGGCCTCGGTGATGACCCAAAACTTGGTTGTTTCAATCCACGCGCCCGCACGGGGCGCGACTGCCCGTGCGCCTTCGTCGCTGCGGATTGTGTTGTTTCAATCCACGCGCCCGCACGGGGCGCGACCCGTAGCGCCAAATGCATTCAACCTCAATCTGGTTTCAATCCACGCGCCCGCACGGGGCGCGACTCGAAAGGCCTGGAATTCGTCAAAGACTCGGTCGTTTCAATCCACGCGCCCGCACGGGGCGCGACCCGATAAAGCAGGATTCGTCGGCGGTAGTGAGCTGTTTCAATCCACGCGCCCGCACGGGGCGCGACCGCTATTTAATCGATACAGTGCTAGAGGGCGGGTTTCAATCCACGCGCCCGCACGGGGCGCGACGATCGTTTTTGATTGGTGTGCCCTGGTGTAGCGTTTCAATCCACGCGCCCGCACGGGGCGCGACGTCAGTTCGTTTTGCGTCATTCGGCCCTCCGGGTTTCAATCCACGCGCCCGCACGGGGCGCGACTCGTTCGATAAAAGTGAGCGTCGCCGGTCACGACTCCGGGTTTCAATCCACGCGCCCGCACGGGGCGCGAC

>NC_016112|3|2|2435093-2435704|PILER-CR
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTACTCGATGCCCAGTTTCGTGTTCGCGTCGGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGCTGGAGCAATCGCAGCAATTGGGATGGCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAGTCGACTCCTTGCGTCGATGCTCCTGTGTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	AGCGTTTCCTCGTTCTCTTGACCCGTATTTGC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTATCTCCTATGTATGGATACCCATCAGTCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GATCGCCCTGTGATCTGTGTTAACGTCAAATT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAGCGATTCGGCGCGTGTCGCAGATGTCTTGAC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTAATATAACTTCTACTGCTGTCAATTACGCTA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GGCTACGACTGGCACATGATCGTCGACAACTGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGACTTCGGCGCTTGGCCGAAAAGCACGGTATTACAGTTTCAATCCACGCGCCCGCACGGGGGGCGCCGTTTGGATTAACGCCGTTTCGGCTTTTTTGTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCCGTGGTGTTCATATTTACTGCGGAGGATTTA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCGAGAGGATCCGATGTATCAGGCGGTATTGGT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAATGAACCGTTGCCGAAAAACGCATTGGCCA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	AAAATTGGGAGCAAGCAAAAGTGGTTGGATTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTGACGCGCTTCGTCACGGGGTCAGCGCATTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTGATGTCGAGGTTCTTTTTGTTGCGATCTAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGAGAGCCGCCCGGATGCCAGCGCAAATTGGATT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ACGATTAAAGCTATCTATCGGATGGCGGTTGA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GAACTGAGCTCAGAACAAACTTATTGGATAGCAGGTTGA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CTGATTGTTTTGTTCTCATACCGATACGAAAAATTCGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ATTTTTGAATCCGACGCCTCGCTATTTTCCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CACATGAACGCTGAAAACGCCCTATTGCAATAC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCCCGCTAAGATTTCGACATTGCAGGGCGGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ATGAGCGATCGGCCTCGGTGATGACCCAAAACTTGGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TGCCCGTGCGCCTTCGTCGCTGCGGATTGTGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CCGTAGCGCCAAATGCATTCAACCTCAATCTG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TCGAAAGGCCTGGAATTCGTCAAAGACTCGGTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CCGATAAAGCAGGATTCGTCGGCGGTAGTGAGCT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGCTATTTAATCGATACAGTGCTAGAGGGCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GATCGTTTTTGATTGGTGTGCCCTGGTGTAGC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTCAGTTCGTTTTGCGTCATTCGGCCCTCCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TCGTTCGATAAAAGTGAGCGTCGCCGGTCACGACTCCGG


>NC_016112|3|3|2435093-2437273|CRISPRCasFinder
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTACTCGATGCCCAGTTTCGTGTTCGCGTCGGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGCTGGAGCAATCGCAGCAATTGGGATGGCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAGTCGACTCCTTGCGTCGATGCTCCTGTGTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	AGCGTTTCCTCGTTCTCTTGACCCGTATTTGC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTATCTCCTATGTATGGATACCCATCAGTCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GATCGCCCTGTGATCTGTGTTAACGTCAAATT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAGCGATTCGGCGCGTGTCGCAGATGTCTTGAC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTAATATAACTTCTACTGCTGTCAATTACGCTA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GGCTACGACTGGCACATGATCGTCGACAACTGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTCGGCGCTTGGCCGAAAAGCACGGTATTACA
GTTTCAATCCACGCGCCCGCACGGGGGGCGCC	GTTTGGATTAACGCCGTTTCGGCTTTTTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCCGTGGTGTTCATATTTACTGCGGAGGATTTA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCGAGAGGATCCGATGTATCAGGCGGTATTGGT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAATGAACCGTTGCCGAAAAACGCATTGGCCA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	AAAATTGGGAGCAAGCAAAAGTGGTTGGATTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTGACGCGCTTCGTCACGGGGTCAGCGCATTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTGATGTCGAGGTTCTTTTTGTTGCGATCTAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGAGAGCCGCCCGGATGCCAGCGCAAATTGGATT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ACGATTAAAGCTATCTATCGGATGGCGGTTGA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GAACTGAGCTCAGAACAAACTTATTGGATAGCAGGTTGA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CTGATTGTTTTGTTCTCATACCGATACGAAAAATTCGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ATTTTTGAATCCGACGCCTCGCTATTTTCCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CACATGAACGCTGAAAACGCCCTATTGCAATAC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCCCGCTAAGATTTCGACATTGCAGGGCGGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ATGAGCGATCGGCCTCGGTGATGACCCAAAACTTGGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TGCCCGTGCGCCTTCGTCGCTGCGGATTGTGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CCGTAGCGCCAAATGCATTCAACCTCAATCTG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TCGAAAGGCCTGGAATTCGTCAAAGACTCGGTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CCGATAAAGCAGGATTCGTCGGCGGTAGTGAGCT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGCTATTTAATCGATACAGTGCTAGAGGGCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GATCGTTTTTGATTGGTGTGCCCTGGTGTAGC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTCAGTTCGTTTTGCGTCATTCGGCCCTCCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TCGTTCGATAAAAGTGAGCGTCGCCGGTCACGACTCCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC

>NC_016112|3|2|2435093-2437273|CRT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTACTCGATGCCCAGTTTCGTGTTCGCGTCGGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGCTGGAGCAATCGCAGCAATTGGGATGGCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAGTCGACTCCTTGCGTCGATGCTCCTGTGTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	AGCGTTTCCTCGTTCTCTTGACCCGTATTTGC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTATCTCCTATGTATGGATACCCATCAGTCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GATCGCCCTGTGATCTGTGTTAACGTCAAATT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAGCGATTCGGCGCGTGTCGCAGATGTCTTGAC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTAATATAACTTCTACTGCTGTCAATTACGCTA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GGCTACGACTGGCACATGATCGTCGACAACTGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTCGGCGCTTGGCCGAAAAGCACGGTATTACA
GTTTCAATCCACGCGCCCGCACGGGGGGCGCC	GTTTGGATTAACGCCGTTTCGGCTTTTTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCCGTGGTGTTCATATTTACTGCGGAGGATTTA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCGAGAGGATCCGATGTATCAGGCGGTATTGGT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAATGAACCGTTGCCGAAAAACGCATTGGCCA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	AAAATTGGGAGCAAGCAAAAGTGGTTGGATTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTGACGCGCTTCGTCACGGGGTCAGCGCATTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTGATGTCGAGGTTCTTTTTGTTGCGATCTAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGAGAGCCGCCCGGATGCCAGCGCAAATTGGATT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ACGATTAAAGCTATCTATCGGATGGCGGTTGA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GAACTGAGCTCAGAACAAACTTATTGGATAGCAGGTTGA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CTGATTGTTTTGTTCTCATACCGATACGAAAAATTCGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ATTTTTGAATCCGACGCCTCGCTATTTTCCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CACATGAACGCTGAAAACGCCCTATTGCAATAC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCCCGCTAAGATTTCGACATTGCAGGGCGGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ATGAGCGATCGGCCTCGGTGATGACCCAAAACTTGGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TGCCCGTGCGCCTTCGTCGCTGCGGATTGTGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CCGTAGCGCCAAATGCATTCAACCTCAATCTG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TCGAAAGGCCTGGAATTCGTCAAAGACTCGGTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CCGATAAAGCAGGATTCGTCGGCGGTAGTGAGCT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGCTATTTAATCGATACAGTGCTAGAGGGCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GATCGTTTTTGATTGGTGTGCCCTGGTGTAGC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTCAGTTCGTTTTGCGTCATTCGGCCCTCCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TCGTTCGATAAAAGTGAGCGTCGCCGGTCACGACTCCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC

>NC_016112|3|3|2435798-2437273|PILER-CR
	GTACTCGATGCCCAGTTTCGTGTTCGCGTCGGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGCTGGAGCAATCGCAGCAATTGGGATGGCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAGTCGACTCCTTGCGTCGATGCTCCTGTGTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	AGCGTTTCCTCGTTCTCTTGACCCGTATTTGC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTATCTCCTATGTATGGATACCCATCAGTCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GATCGCCCTGTGATCTGTGTTAACGTCAAATT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAGCGATTCGGCGCGTGTCGCAGATGTCTTGAC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTAATATAACTTCTACTGCTGTCAATTACGCTA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GGCTACGACTGGCACATGATCGTCGACAACTGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGACTTCGGCGCTTGGCCGAAAAGCACGGTATTACAGTTTCAATCCACGCGCCCGCACGGGGGGCGCCGTTTGGATTAACGCCGTTTCGGCTTTTTTGTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCCGTGGTGTTCATATTTACTGCGGAGGATTTA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCGAGAGGATCCGATGTATCAGGCGGTATTGGT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CAATGAACCGTTGCCGAAAAACGCATTGGCCA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	AAAATTGGGAGCAAGCAAAAGTGGTTGGATTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTGACGCGCTTCGTCACGGGGTCAGCGCATTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TTGATGTCGAGGTTCTTTTTGTTGCGATCTAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGAGAGCCGCCCGGATGCCAGCGCAAATTGGATT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ACGATTAAAGCTATCTATCGGATGGCGGTTGA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GAACTGAGCTCAGAACAAACTTATTGGATAGCAGGTTGA
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CTGATTGTTTTGTTCTCATACCGATACGAAAAATTCGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ATTTTTGAATCCGACGCCTCGCTATTTTCCAG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CACATGAACGCTGAAAACGCCCTATTGCAATAC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GCCCGCTAAGATTTCGACATTGCAGGGCGGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	ATGAGCGATCGGCCTCGGTGATGACCCAAAACTTGGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TGCCCGTGCGCCTTCGTCGCTGCGGATTGTGTT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CCGTAGCGCCAAATGCATTCAACCTCAATCTG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TCGAAAGGCCTGGAATTCGTCAAAGACTCGGTC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CCGATAAAGCAGGATTCGTCGGCGGTAGTGAGCT
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	CGCTATTTAATCGATACAGTGCTAGAGGGCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GATCGTTTTTGATTGGTGTGCCCTGGTGTAGC
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	GTCAGTTCGTTTTGCGTCATTCGGCCCTCCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC	TCGTTCGATAAAAGTGAGCGTCGCCGGTCACGACTCCGG
GTTTCAATCCACGCGCCCGCACGGGGCGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016112.1\|WP_014148623.1\|2430349_2431819_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|273830
NC_016112.1\|WP_014148621.1\|2425946_2427161_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_016112.1\|WP_014148632.1\|2438793_2439420_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_016112.1\|WP_014148624.1\|2432062_2432671_-\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014148620.1\|2425227_2425842_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379522
NC_016112.1\|WP_014148633.1\|2439480_2440344_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|187820
NC_016112.1\|WP_014148622.1\|2427167_2430353_+\|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|273335
NC_016112.1\|WP_046061106.1\|2442367_2443072_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187782
NC_016112.1\|WP_014148639.1\|2449108_2450434_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223540
NC_016112.1\|WP_026130023.1\|2437451_2437742_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_016112.1\|WP_014148638.1\|2448015_2448285_-\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014148619.1\|2424038_2424491_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|238612
NC_016112.1\|WP_014148634.1\|2440340_2442371_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NC_016112.1\|WP_162472945.1\|2432923_2433094_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223683
NC_016112.1\|WP_046061527.1\|2433086_2434094_-\|virulence-protein-RhuM/Fic/DOC-family-protein	unknown	unknown	gnl\|CDD\|379118
NC_016112.1\|WP_014148631.1\|2437756_2438791_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_016112.1\|WP_014148628.1\|2434475_2434670_-\|type-II-toxin-antitoxin-system-VapB-family-antitoxin	unknown	unknown	gnl\|CDD\|378324
NC_016112.1\|WP_014148627.1\|2434104_2434473_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|224404
NC_016112.1\|WP_014148637.1\|2445981_2447232_-\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_016112.1\|WP_046061528.1\|2443081_2445538_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688

Protein	Function_ID	Function_description	E-value
NC_016112.1\|WP_014148623.1\|2430349_2431819_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|273830	TIGR01845, Outer_membrane_protein_OprM, efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. Members of this model comprise a subfamily of the Outer Membrane Factor (TCDB 1.B.17) porins. OMF proteins operate in conjunction with a primary transporter of the RND, MFS, ABC, or PET systems, and a MFP (membrane fusion protein) to tranport substrates across membranes. The complex thus formed allows transport (export) of various solutes (heavy metal cations; drugs, oligosaccharides, proteins, etc.) across the two envelopes of the Gram-negative bacterial cell envelope in a single energy-coupled step. Current data suggest that the OMF (and not the MFP) is largely responsible for the formation of both the trans-outer membrane and trans-periplasmic channels. The roles played by the MFP have yet to be determined. [Cellular processes, Detoxification, Transport and binding proteins, Porins].	2.52136e-91
NC_016112.1\|WP_014148621.1\|2425946_2427161_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	6.88235e-81
NC_016112.1\|WP_014148632.1\|2438793_2439420_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	6.82683e-37
NC_016112.1\|WP_014148634.1\|2440340_2442371_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	5.03931e-167
NC_016112.1\|WP_014148620.1\|2425227_2425842_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379522	pfam14246, TetR_C_7, AefR-like transcriptional repressor, C-terminal region. This family comprises the C-terminal domain of transcriptional regulators of the TetR family. It includes the AefR transcriptional regulator from P. syringae. It is found in association with pfam00440.	1.09283e-21
NC_016112.1\|WP_014148633.1\|2439480_2440344_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	2.03518e-113
NC_016112.1\|WP_014148622.1\|2427167_2430353_+\|multidrug-efflux-RND-transporter-permease-subunit	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NC_016112.1\|WP_046061106.1\|2442367_2443072_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.79936e-94
NC_016112.1\|WP_014148639.1\|2449108_2450434_-\|ATP-binding-protein	gnl\|CDD\|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	3.86744e-38
NC_016112.1\|WP_026130023.1\|2437451_2437742_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.32256e-29
NC_016112.1\|WP_014148619.1\|2424038_2424491_-\|nucleoside-deaminase	gnl\|CDD\|238612	cd01285, nucleoside_deaminase, Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on the substrate. The functional enzyme is a homodimer. Cytosine deaminase catalyzes the deamination of cytosine to uracil and ammonia and is a member of the pyrimidine salvage pathway. Cytosine deaminase is found in bacteria and fungi but is not present in mammals; for this reason, the enzyme is currently of interest for antimicrobial drug design and gene therapy applications against tumors. Some members of this family are tRNA-specific adenosine deaminases that generate inosine at the first position of their anticodon (position 34) of specific tRNAs; this modification is thought to enlarge the codon recognition capacity during protein synthesis. Other members of the family are guanine deaminases which deaminate guanine to xanthine as part of the utilization of guanine as a nitrogen source.	1.28099e-37
NC_016112.1\|WP_162472945.1\|2432923_2433094_-\|hypothetical-protein	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	4.35594e-09
NC_016112.1\|WP_046061527.1\|2433086_2434094_-\|virulence-protein-RhuM/Fic/DOC-family-protein	gnl\|CDD\|379118	pfam13310, Virulence_RhuM, Virulence protein RhuM family. There are currently no experimental data for members of this group or their homologs. However, these proteins are implicated in virulence/pathogenicity because RhuM is encoded in the SPI-3 pathogenicity island in Salmonella typhimurium.	1.76403e-36
NC_016112.1\|WP_014148631.1\|2437756_2438791_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	7.38224e-179
NC_016112.1\|WP_014148628.1\|2434475_2434670_-\|type-II-toxin-antitoxin-system-VapB-family-antitoxin	gnl\|CDD\|378324	pfam09957, VapB_antitoxin, Bacterial antitoxin of type II TA system, VapB. VapB is the antitoxin of a bacterial toxin-antitoxin gene pair. The cognate toxin is VapC, pfam05016. The family contains several related antitoxins from Cyanobacteria and Actinobacterial families. Antitoxins of this class carry an N-terminal ribbon-helix-helix domain, RHH, that is highly conserved across all type II bacterial antitoxins, which dimerizes with the RHH domain of a second VapB molecule. A hinge section follows the RHH, with an additional pair of flexible alpha helices at the C-terminus. This C-terminus is the Toxin-binding region of the dimer, and so is specific to the cognate toxin, whereas the RHH domain has the specific function of lying across the RNA-binding groove of the toxin dimer and inactivating the active-site - a more general function of all antitoxins.	5.26948e-10
NC_016112.1\|WP_014148627.1\|2434104_2434473_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|224404	COG1487, VapC, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	4.5284e-09
NC_016112.1\|WP_014148637.1\|2445981_2447232_-\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	6.70222e-176
NC_016112.1\|WP_046061528.1\|2443081_2445538_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.0595e-52

>NC_016112.1|WP_014148628.1|2434475_2434670_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin
MRTTVVLDDELLEKAQALTNLKEKSSLIKEALKALIERESAKRLASLGGIAPDLQPIPRRQTEL
>NC_016112.1|WP_014148627.1|2434104_2434473_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MPVLVDTSVWIDHFRKKEPALVALLESAQVLGHPFVRGELALGNLPQRHTLLELLDNLPQTPVAFGEEINRFIEANTLFGLGIGFVDVHLLASAKLALNATLWTRDNRLLAVATQLNVGYQP
>NC_016112.1|WP_046061527.1|2433086_2434094_-|virulence-protein-RhuM/Fic/DOC-family-protein
MTSTNQPQQIAIYQNEDGSIRIDVHLEQDTVWLNQRQLSALFDKDVRTINEHIRNILAEQELEAEATIRKFRIVQQEGKRQVSRDVEHYNLDMIISVGYRVNSKKGTQFRIWANTILKQYLLQGYALNEQKLRDSREKLADLQQAIALSSRLVHHKALSASESQGILAILEQYSHALTVLDDYDHQRLVIAGTQKATQTPIGYEEAIAQIRLWREQEQLSGLFGNEKDDSFKSSLATIYQTFGGEELYPSIEEKAANLLYFIVKNHSFSDGNKRIAAAIFAWFLQRHDYLYNANGEKRIADNALVAFTLLIAESKPEEKDTIVKVIINLINGNNG
>NC_016112.1|WP_162472945.1|2432923_2433094_-|hypothetical-protein
MDDSLDGSELAKHHTTKQQRKALAERMKDNNDEVKLVIVRNMWLTGFDAASIVEVQ
>NC_016112.1|WP_014148624.1|2432062_2432671_-|hypothetical-protein
METVSYKELLSIVAIVLTFLATAPYIYSVLKGATKPHVFSWVIWGTTTFVVFLAQLKNQGGVGAWPIGVSGILTIFIAILAFAKRGDVTIAKTDWVFLITALSSLPLWYFTSDPLWAVVILTTVDVLGFGPTIRKAYHQPTSEPLNFYALFAIRNLLVVMALEHHSLTTVLFPAVLGLTCVFIMILMMYRRLAIIVVSQGEQ
>NC_016112.1|WP_014148623.1|2430349_2431819_+|efflux-transporter-outer-membrane-subunit
MMKQVIFTNSSRAWSNLGLGLTSLCLTLLSACAVGPDYRLPFIETPQEFGQAVHPEFSKEGIELNWWTLFEDSQLNDLVEQAVEHNYDLKTAYANLEEARALYLESGLDLVPVINSRAGYTDQKRSFGAMNNRTFAPRELKLYNIGFDAFWELDLFGRVRRSVEASDDEVDAQEAILRDLSVSLIAEVARNYFELRGLQNQLAVAQKNAENQAETAEITQSRLVNGRGTELDTSRALAQLEATKAGIPPLKSAIQKTIHRLSVLTGQFPGALTERLSRPAPLPKLPETIQIGSPAELLRRRPDIRIAERTLASSTARIGVATADLFPRVTFVGSIALEASSLSGLATGGSDAFSAGPRITWAALDLGRVLARIDAADAHAEADLAQYEQTVLNALEETENALINYNQERARRKLLAAAAEASQRAQELAHLRFNAGLSDFLTVLDIESRLLQDQSSLAQSETATATALAALYKALGGGWETTLETNDDD
>NC_016112.1|WP_014148622.1|2427167_2430353_+|multidrug-efflux-RND-transporter-permease-subunit
MYRFTHFFIDRPIFASVLSILIVMVGGLALIALPIAQYPEIAPPTVMVSTVYPGANAAVVAETVATPIEQEVNGVEDMLYLSSQSTNSGNMALTITFKPGTDLDKAQVQVQNRVALAEPKLPEEVRRQGISVKKRSPDLSLVVNLISPDQRYDSVYLSNYALLQIKDTLARLPGVGEILVFGARDYSMRLWLDPEKIAARNMTASDVVNAVREQNIQVAAGVVGQQPSPEATDYQYTVSTLGRLTDPEQFADIVIKQGSDGKITRLKDVARIELGAKDYNSSLYLDGEQTVGLAVFQLPGSNALDTKKAIEAEMEKMKTHFPEGLDYTLVYDTVVFIQQSIDAVVKTLFEALLLVVIVVIVFLQNWRAAIIPLLAVPVSLIGTFAVMAGMGLSLNTLSLFGLVLAIGIVVDDAIVVVENVERHIAEGMSSRDATRKAMEEVIGPIIATTLVLVAVFIPTAFITGVSGAFYKQFALTIAVSTLISTLNSLTLSPAMCALLLDRAHGNNDAFTRLLDRLFGWFFAGFNRFFDRFGEGYARLVGRLIRMTVLVLTLYVGLNGLNWLAFEKVPTGFIPQQDQGYLILYTQLPDAASLSRTQDVVKEATRIILDTEGVAHVIAYSGWSVLTGANQSNVATMFTPLDKFKDRAGKPELHANEIIKKLQQRLAQIPDAHIAVFAPPPVRGMGSVGGFKLQIQDRTSAGIDALQDVANEMIAEGNQQPGLTGLFTTFRASVPQLFLDVDRTRAKAMDVPLKEVFETLQIYLGSMYVNDFNSFGRTYQVVAQADADYRMHPEDITELKTRNAAGGIVPLGSLIDVKKITGPDKITRYNMYPAAEINGGTLPGISSGQAIDIMSRLLDQQLPPGFGYEWTELSLQQVLAGNVAFLVFPLSVVFVFLVLAAQYESWSLPLAIILIVPMCILSSMTGIWLSGMDNNIFTQIGFIVLVALASKNAILIVEFAKQRQESGLDRFAAVMDASRVRLRPILMTSFAFIMGVLPLVLAQGAGAESRRLLGTAVFSGMIGVTLFGLLLTPVFYVSVQGLVQRLTSSRKQKPQHSTSDSE
>NC_016112.1|WP_014148621.1|2425946_2427161_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MNPKTEPALAIYRPSVNEVSLTSGGNIPSLSPSLLAFWVITVIAIALTGCGDTAEIQAPPAAKVKIAHPLSRDVTEWDEFTGRIEAIEAVEVRARVGGHLEKVNFFAGEKVKKGDLLFTIDPKPYQAQLNLAQAELERAKSKRELAQNDLERAENLLKAKAISIEEYDGRSKGLREASASVQAAEANVYRAKLDLEYTRIHAQIDGRVGRELITTGNLVNGGGAATLLTHIVSIDPVYVYIDADERSVLKYKRQLSGRENLQGMPMQLNLTDESDFPHRGTLDYIAPSADTDTGTVTLRGVFENTHNLLSPGFFARVRIQGGAPYPALLLPDRAIGTDQAQRFVWVLNQDDQAEYRKVIPGARIDGLRVISEGLTAEDKVVIEGQQKVRPGAKVAPELVTFGGE
>NC_016112.1|WP_014148620.1|2425227_2425842_-|TetR/AcrR-family-transcriptional-regulator
MVKCGRPPKGQECESRERLLDSALQLFLEHGYGDLNMETIAKDAHVSMRTIYSRFGNKAGLFGAVIKRCSDQFVDRLPENLEPGEALGVFAKHYVHLITRPDAVRIRTILIGESLRFPELAAKFYEQGPQRARDTLVDYFVKKQQEGHFSDVSPRVLADYFLSCLRNEHFQKLQLGLASTPEEAEIDLWVRQTVDLFLHGCLKK
>NC_016112.1|WP_014148619.1|2424038_2424491_-|nucleoside-deaminase
MNYSNMLTVAFEEARTGFDEGGVPVGAALFDCEGRVLGRGRNRRVQDGDPSVHGETDAFRKAGRQTNYRDKILVTTLAPCWYCSGLIRQFNIGTVVVGESVNFSGHLDWLREAGVNVIELNDADCIELMRRFIEQSPHIWFEDIGECDNA
>NC_016112.1|WP_026130023.1|2437451_2437742_-|CRISPR-associated-endonuclease-Cas2
MMILVTYDVSFKTETGPKRLRKIARLCQVFGQRVQYSVFEIEVDMAQWTQLKNDLINVMDPEEDSLRFYYLGNNWERKVEHVGAKKVLDLNGLLLM
>NC_016112.1|WP_014148631.1|2437756_2438791_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRPLRNVIYIQTQNSWLHKDNENLVLKVDKELKARVPIHKLQGLVCFGQVSISPYLMAHCAENGITITYLNQFGKFLARVEGPVSGNVLLRRTQHLTGADTAKSVAIARTMLTGKLYNQRSVLRRYLRDYGNQAEQQNMTHDLAAAEKRLSRCMQQLADCNGIDTLMGREGEAAQVYFGVFQHLIRQPGFEFDARRRRPPTDPVNALLSFCYTLLTHDCRSALETVGLDPASGFLHQLRSGRPSLALDLVEEFRPMVERFVLSLINKRQLALNDFETWPNGSVTLKEEPRKTLLAAWQDRKQDTLMHPWFEETVPVGLLPWLQAQILARFLRGDCDSYVPFLWK
>NC_016112.1|WP_014148632.1|2438793_2439420_-|CRISPR-associated-protein-Cas4
MNDLEPIYLSRLQHYLYCPRQFALIELEDVWLENRFTAEGQVLHQRVNQPDRETRGDIRTVRALRLSHAELGIEGVADVVEYHRQSDGTEVPFPIEYKRGRPKAHRADEVQLCAQALCLEDMENVEVPEGALFYGEVRRRHAVVFDQTLRELTLETITGCREIIRSKETPKADYQAKKCRNCSLLEQCHPQIFGKSASAWLARQLAQD
>NC_016112.1|WP_014148633.1|2439480_2440344_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSELDRNTLSHKIDFAVIFSVDHANPNGDPLNGNRPRTDYDGYGEMTDVCLKRKIRDRLQSESFSIFVQSDEKKTDGMTSLKNRAEAEPPIGLGKDAFNPKKQSKDQTAQMACAKWFDVRAFGQVFAFGKDGDAAGVSIPIRGPVTIQSAFSVEPVSITSTQITKSVNSEGDGSKKGADTMGMKHRVDHAVYVAYGAITPQLAEKTGFSDDDAEAIKKVLPRLFEGDASSARPEGSMAVKKVIWWQHNSRSGQYSSAKVHGSLTVNADGSYELETLPGLQPEEKEGF
>NC_016112.1|WP_014148634.1|2440340_2442371_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWMEKLYQTYEAAILLDLPIEQRLMPISHTNQNAHINIVINGEGNFKRATVLEKTQIVLPATEQSAGRTGTKPPPHPLADKLQYVAKDYSEFITYKPSFFEEYYKLLKSWCDSKFSHPKANAVLEYVKKGRVISDLVENKILFLDQEKKYLLRQWTSDSSDEMPLIFKVLPKEKKQVDQGAALVCWSVEIENQPDSDTWKDISLQNSWNTFISANEGVGGLCFVTGNFTALASNHPAKIRHTGDKAKLISFNDFNGFTVLGKFTDTKESFKKNGSQSVGVGLLTTQKAHNALRWLISRQGYRNGDQVYVAWAVSGKPIPEPLADTWSFLNTGDFDLEEVDQAEAPEQTDDTVDHSIDLGQSYAQQLSKKMAGYRAELTANEQIVVMGIDSATPGRMGILYYRELFRDDFFNRLESWHTEFSWPQRHTLEIPNDTGRKPKTKVIWPVSSPVPIAIAKAAYGEKVTDNLKKKVIERLVPCIVDGQPFPWDLVDNCIRKATNRNAYASDGQWLWEKNLAIACALFKGYYRRHPNSNQRRNYAMALEENNRSRDYLYGRLLAIAERIEEVALNVGGENRSTTAARLMQRFADRPYETWRSIELALQPYIQRLRVSRAGFLTNRQKELDAVIALFNGEDFRSKAPLSGEFLLAYHCQRQKFKTKTDTHEPNETEAQGDSE
>NC_016112.1|WP_046061106.1|2442367_2443072_-|type-I-C-CRISPR-associated-protein-Cas5
MKNSISFRLWGRHALFTDPVTRIGGEKCSYHLPTYEAIKGVLKSIYWKPTLIWYVDKVRVIKPLRTQTKGTKPLVWNGGNTLAIYTFLRDVEYQVQAHFEWNEHRPELAKDRIDGKHYSIVQRMLERGGRQDIFLGTRDCQAYVEPCEFGSIEGAYDEIDELAFGLMFHSFAYPDETGIDELHSRFWHATMKKGILEFPRPENCPVSRFVRPMRRKPFGIGSNLLAVEDEENRR
>NC_016112.1|WP_046061528.1|2443081_2445538_-|CRISPR-associated-helicase/endonuclease-Cas3
MKIKDTLYVAHVRSNDKKIQTLEEHLIDVAEIAKKLATKINLPEAGELIGLLHDFGKYSTEFQNYLQSATGLIDPDIDNEAVDAKALKGKIDHSSAGAQWIWQELSRYGNNGEGRLCGQIMAVCIASHHSGLIDCLKPDGSNGFNVRMQKDDVRTHLAECKENADSQILERAKKLMDKPLLKAMLEQIRVMMMSGSKQSTTIREFYLGFWTRFLFSCLIDADRIDSADFETPGNACYRNKNDLQLTVAIERLELFLAGFSNKPTESNTPIDGIRREISEVCKNRAHEPQGIYTLTVPTGGGKTYASLRYALHHAQKHKLERIIYVIPYTSIIEQNAAAIRSALERESDAYPWVLEQHSNLEPERQTWHSKLAAENWDAPIVLTTMVQFLETLFGGGTRGVRRLHQLANSVVIFDEIQTLPIQCTHLFCNALNFLADHAGMTAVLCTATQPVLDRLRASDKGQLSLPQNSELMPDISGLFDQLKRVVISDKTKPEGWSEDEIAELALTELDTKGNCLVIVNTKAWAQALYLKCAETVDIESLFHLSTGQCAAHRKALFKLMRQRLADGLPVLCISTQLIEAGVDIDFAGVVRFLAGLDSIAQAAGRCNRNGHLSTATVHIVNPARETISQLIDIKVGQEKTKRVLSEIEDEDLLSPEAMRRYFQYYFYDRADDMSYPLSAKQVGRDDSLLNLLSQNKYNVGVGAALHLKQSFMTAGNVFKAIDAPTHSVIVPYLEGKQLLVELGGIAKRFEARRFRECLQRAQQYSVNVFPNVWRRLVEQQAVYEIQPGEGIYGLDERYYSEAFGLSTEPVSKAEAIIL
>NC_016112.1|WP_014148637.1|2445981_2447232_-|group-II-intron-reverse-transcriptase/maturase
MSEAKPFVISKWQVMRAFELVKANAGAAGVDRQSLADFERNLKDNLYKLWNRLSSGSYFPPPVKAVAIPKKAGGERILGIPTVSDRIAQMVVKLEFEPQVEPHFLPDSYGYRPNKSALDAVGVTRERCWRYDWVLEFDIKGLFDNIPHDLLLKAVYKHTDTAWVRLYIERWLTVPMQMPNGELSSRGKGTPQGGVVSPVLSNLFLHYVFDKWLQKHYSDTPWCRYADDGLVHCRSEAEAKHMLEALKQRFQSCGLELHPVKTKIVYCKDGSRKGRYKHTSFDFLGYTFRRRLCRNRKRNSVFVNFTPAVSKAALKSMRGKVRKLRVRTRTELSLGQIAQWLNPIIRGWIGYYGCYTRSALYGMCRHVNMTLVRWVRRKFKPLRQHKIKAMLFLEKIADQHPNLFAHWRAGMIGAFA
>NC_016112.1|WP_014148638.1|2448015_2448285_-|hypothetical-protein
MKAKDFDKKFDQGKKDIIDDLDLSTARRVNQEQKRINVDFPSWVVDSLDREAARIGVTRQLIIKVWLVERLKAEAANKALNGDASNGAH
>NC_016112.1|WP_014148639.1|2449108_2450434_-|ATP-binding-protein
MNVDIVNLEIALNWLKSFIEDCLYSRLRKPSEIEIKSLSFYSSESWLTEFIEKYNPSLEEFVVLLLAIVPHLQPHFFNKLISEFLPEGGDFPEFGGVKGTNHRGILPTGETAQFILAGDDLEKRLEIQKIFNDDHWFAKQKILRLDPVPEGEPIMSGRLVLDPEIVEWLTLGTISKPRFSIDFPAEYIETEMAWDDLVLPPSTFKQIREIEHWIEYNDTLLQDWGMKKKIKPGYRALFYGPPGTGKTLTATLLGKQTGKDVFRIDLSRVVSKYIGETEKNLSRLFDKAENKDWILFFDEADALFGKRTDIRDAHDKYANQEVAYLLQRIENYNGLVILASNQRANIDEAFVRRFQAIIHFPMPGADERYEIWRKTIPEQLEVHLDIDWRQVANRYELSGASILNVTHYCAVEIMAAQSVKLDLKRLETAIQREFIKEGKVV

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Crispr_ID: NC_016112_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016112_4

3711360-3711431

Orphan

Consensus_repeat	Method
CTGCATTCACGCCATCCATGGCG	CRISPRCasFinder

1 spacers

DinG

The CRISPR arrays of NC_016112_4

>merge|NC_016112|4|3711360-3711431|CRISPRCasFinder
CTGCATTCACGCCATCCATGGCGTTTGCAGATTTTTGCTCCTGCAAAATCTGCATTCACGCCATCCATGGCA

>NC_016112|4|4|3711360-3711431|CRISPRCasFinder
CTGCATTCACGCCATCCATGGCG	TTTGCAGATTTTTGCTCCTGCAAAAT
CTGCATTCACGCCATCCATGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_016112.1\|WP_014149630.1\|3713143_3713617_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|224146
NC_016112.1\|WP_014149625.1\|3705692_3706727_-\|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	unknown	unknown	gnl\|CDD\|234858
NC_016112.1\|WP_014149624.1\|3703763_3705683_-\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NC_016112.1\|WP_014149629.1\|3712609_3713134_+\|glycine-cleavage-system-regulatory-protein	unknown	unknown	gnl\|CDD\|225337
NC_016112.1\|WP_014149628.1\|3711896_3712514_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|377516
NC_016112.1\|WP_046061636.1\|3702423_3703044_-\|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl\|CDD\|183245
NC_016112.1\|WP_014149638.1\|3723180_3723699_-\|ATP-dependent-zinc-protease	unknown	unknown	gnl\|CDD\|226553
NC_016112.1\|WP_014149620.1\|3700896_3701712_-\|segregation/condensation-protein-A	unknown	unknown	gnl\|CDD\|224273
NC_016112.1\|WP_014149636.1\|3719755_3721210_+\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|227122
NC_016112.1\|WP_014149637.1\|3721986_3723141_-\|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|369642
NC_016112.1\|WP_014149626.1\|3707082_3709167_+\|elongation-factor-G	unknown	unknown	gnl\|CDD\|234569
NC_016112.1\|WP_014149639.1\|3724388_3725147_-\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014149619.1\|3699770_3700430_-\|SMC-Scp-complex-subunit-ScpB	unknown	unknown	gnl\|CDD\|377219
NC_016112.1\|WP_014149621.1\|3701751_3702408_-\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100079
NC_016112.1\|WP_014149623.1\|3703083_3703767_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl\|CDD\|274750
NC_016112.1\|WP_014149631.1\|3713716_3715129_+\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224787
NC_016112.1\|WP_014149634.1\|3717049_3719161_-\|glycogen-debranching-protein-GlgX	unknown	unknown	gnl\|CDD\|200465
NC_016112.1\|WP_014149627.1\|3709900_3711232_+\|flavohemoglobin-expression-modulating-QEGLA-motif-protein	unknown	unknown	gnl\|CDD\|369651
NC_016112.1\|WP_014149618.1\|3698911_3699751_-\|pseudouridine-synthase	unknown	unknown	gnl\|CDD\|182659
NC_016112.1\|WP_014149633.1\|3715720_3716821_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701

Protein	Function_ID	Function_description	E-value
NC_016112.1\|WP_014149630.1\|3713143_3713617_+\|peroxiredoxin	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	4.88654e-76
NC_016112.1\|WP_014149625.1\|3705692_3706727_-\|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	gnl\|CDD\|234858	PRK00892, lpxD, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional.	1.01229e-134
NC_016112.1\|WP_014149624.1\|3703763_3705683_-\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	7.61052e-162
NC_016112.1\|WP_014149629.1\|3712609_3713134_+\|glycine-cleavage-system-regulatory-protein	gnl\|CDD\|225337	COG2716, GcvR, Glycine cleavage system regulatory protein [Amino acid transport and metabolism].	7.11159e-32
NC_016112.1\|WP_014149628.1\|3711896_3712514_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|377516	pfam05494, MlaC, MlaC protein. MlaC is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. This family of proteins is involved in toluene tolerance, which is mediated by increased cell membrane rigidity resulting from changes in fatty acid and phospholipid compositions, exclusion of toluene from the cell membrane, and removal of intracellular toluene by degradation. Many proteins are involved in these processes.	7.17873e-59
NC_016112.1\|WP_046061636.1\|3702423_3703044_-\|threonylcarbamoyl-AMP-synthase	gnl\|CDD\|183245	PRK11630, PRK11630, threonylcarbamoyl-AMP synthase.	2.87685e-88
NC_016112.1\|WP_014149638.1\|3723180_3723699_-\|ATP-dependent-zinc-protease	gnl\|CDD\|226553	COG4067, COG4067, Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones].	2.38196e-28
NC_016112.1\|WP_014149620.1\|3700896_3701712_-\|segregation/condensation-protein-A	gnl\|CDD\|224273	COG1354, scpA, Rec8/ScpA/Scc1-like protein (kleisin family) [Replication, recombination, and repair].	4.03091e-59
NC_016112.1\|WP_014149636.1\|3719755_3721210_+\|M48-family-metallopeptidase	gnl\|CDD\|227122	COG4783, COG4783, Putative Zn-dependent protease, contains TPR repeats [General function prediction only].	8.98118e-112
NC_016112.1\|WP_014149637.1\|3721986_3723141_-\|PQQ-dependent-sugar-dehydrogenase	gnl\|CDD\|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	8.05533e-172
NC_016112.1\|WP_014149626.1\|3707082_3709167_+\|elongation-factor-G	gnl\|CDD\|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NC_016112.1\|WP_014149619.1\|3699770_3700430_-\|SMC-Scp-complex-subunit-ScpB	gnl\|CDD\|377219	pfam04079, SMC_ScpB, Segregation and condensation complex subunit ScpB. This is a family of prokaryotic proteins that form one of the subunits, ScpB, of the segregation and condensation complex, condensin, that plays a key role in the maintenance of the chromosome. In prokaryotes the complex consists of three proteins, SMC, ScpA (kleisin) and ScpB. ScpB dimerizes and binds to ScpA. As originally predicted, ScpB is structurally a winged-helix at both its N- and C-terminal halves. IN Bacillus subtilis,one Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complex ring-shaped assemblies.	8.84415e-64
NC_016112.1\|WP_014149621.1\|3701751_3702408_-\|site-2-protease-family-protein	gnl\|CDD\|100079	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with a minimal core protein and no PDZ domains.	6.30563e-72
NC_016112.1\|WP_014149623.1\|3703083_3703767_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl\|CDD\|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	3.34435e-70
NC_016112.1\|WP_014149631.1\|3713716_3715129_+\|PhoH-family-protein	gnl\|CDD\|224787	COG1875, COG1875, NYN ribonuclease and ATPase of PhoH family domains [General function prediction only].	0
NC_016112.1\|WP_014149634.1\|3717049_3719161_-\|glycogen-debranching-protein-GlgX	gnl\|CDD\|200465	cd11326, AmyAc_Glg_debranch, Alpha amylase catalytic domain found in glycogen debranching enzymes. Debranching enzymes facilitate the breakdown of glycogen through glucosyltransferase and glucosidase activity. These activities are performed by a single enzyme in mammals, yeast, and some bacteria, but by two distinct enzymes in Escherichia coli and other bacteria. Debranching enzymes perform two activities: 4-alpha-D-glucanotransferase (EC 2.4.1.25) and amylo-1,6-glucosidase (EC 3.2.1.33). 4-alpha-D-glucanotransferase catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. Amylo-alpha-1,6-glucosidase catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. In Escherichia coli, GlgX is the debranching enzyme and malQ is the 4-alpha-glucanotransferase. TreX, an archaeal glycogen-debranching enzyme has dual activities like mammals and yeast, but is structurally similar to GlgX. TreX exists in two oligomeric states, a dimer and tetramer. Isoamylase (EC 3.2.1.68) is one of the starch-debranching enzymes that catalyzes the hydrolysis of alpha-1,6-glucosidic linkages specific in alpha-glucans such as amylopectin or glycogen and their beta-limit dextrins. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_016112.1\|WP_014149627.1\|3709900_3711232_+\|flavohemoglobin-expression-modulating-QEGLA-motif-protein	gnl\|CDD\|369651	pfam08014, DUF1704, Domain of unknown function (DUF1704). This family contains many hypothetical proteins.	2.61302e-175
NC_016112.1\|WP_014149618.1\|3698911_3699751_-\|pseudouridine-synthase	gnl\|CDD\|182659	PRK10700, PRK10700, 23S rRNA pseudouridine(2605) synthase RluB.	4.5972e-104
NC_016112.1\|WP_014149633.1\|3715720_3716821_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	7.31471e-49

>NC_016112.1|WP_014149627.1|3709900_3711232_+|flavohemoglobin-expression-modulating-QEGLA-motif-protein
MAHSSYRERLLALSDRLIQIQKPIQILDSIKWPRNFREQFFAGDSQFLPPADREFYQHQALSFDAVSVYAALKDLSRDITKNLGYNDSLGSILQDTVSQYMRVIDLLHSRGTPDFLIHSHALYGSARDHLLGDNKTLLELGERLCAIFSLPGAKHLNRAHPKEINAETAVVSLRQRLSSHFDDGALSVVLSDGIVSDASAGGDKIKINNNAWFSELDLKVLEVHEGWVHVGTTLNGRLQPWATWLSVGSPRITATQEGLAVLIETLTFSSFPDRARRISDRVIAIDLAEQGADFIEVYRYFLERDVSPHDSYTIAQRVFRGGMVEGGACFTKDLSYVRGFIELVNFIRSATLEGVPELLPMLFAGKVTLDDIPILYEHYLDGLIAEPKYLPPMFRDLNGLYVWFGFASGIAQINIENVQAHFNQLFQNLPRTPNQASEDTEID
>NC_016112.1|WP_014149626.1|3707082_3709167_+|elongation-factor-G
MTDLSHYRNIGIFAHVDAGKTTTTERILKLTGKIHKLGEVHEGESTMDFMDQEAERGITIQSAATTCFWKDHRFNIIDTPGHVDFTIEVYRSLKVLDGGVGVFCGSGGVEPQSETNWRYANDSKVARVIYVNKLDRIGADFYRVVKQVENVLGANPIVMTLPIGTEDKFVGVVDLLTEKAWIWDNSGDPLNYEIQDIPSDMVEDVKQWRAELIEKAVEQDDDVMEKYLEGEEPDIDTLKRCIRKGTIELKLFPTYCGSSFKNKGVQLVLDAVVDYLPSPTEVNPQPEVDLEGNETGNFAVVDPNRPLRALAFKIMDDRYGALTFIRIYSGQLGKGTNVLNTFTGKTERIGRIVEMHADSREEVESAQAGDIVAVLGMKNVQTGHTLCDPKDPATLEPMVFPDPVISMAVAPKDKGASEKLGVALGKMIQEDPSFRVETDIDSGETILKGMGELHLDIKVDILRRTHGVDVIVGKPQVAYRETITQRVEDSYTHKKQSGGSGQYGKIDYFIEPGEPGSGFVFESKVVGGNVPKEYWPAIQKGFELSMAKGVLAGYPCLDFKVTLVDGAFHAVDSSAIAFEIAAKAAYRQSIPKAGPQLIEPIMKIDVFTPEDHVGDVIGDLNRRRGMIKSQEAGVTGVRIKAEAPLSEMFGYIGDLRTMTSGRGQFSMEFSHYLPCPKNVADEVIKETLERNAKK
>NC_016112.1|WP_014149625.1|3705692_3706727_-|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase
MTLILEELAKHCDAEIVGGDKQCSITSAADIKAAAAGQITILNDPKYAQYFSNSQAAACFIKREALHDDPPEHMALLVCKDPEISFIKAIHLLYPATEFPKQISKHACIADSAMIAHDVYIAPFVSIGEGCLIGEGCEILNGAYIGKDVMLGTNCRIHPNAVIYDRSRIGNNVVIHAGAVIGADGFGYKQRNEQHIKVPHVGNIIIEDDVEIGANTCIDRGTLGSTVIGSGSKIDNLVQIGHNNTIGNNVIICGQTGISGSCTIEDNAILAGSAGIADHVKIGHHAVVMARSGVSNDIAPATQVFGSPAKDRKVAWKELAALTKLPELLKKIKDIEIRLGKLEQ
>NC_016112.1|WP_014149624.1|3703763_3705683_-|ATP-dependent-DNA-helicase
MSELEAFFTSSGPLSKVIPGYLPRAAQVEMACAVSDAIEQERHLIAEAGTGTGKTFAYLVPAILSGRKAIVSTGTKNLQDQLFNNDIPVIRKAMSVPFAAALLKGRSNYLCIYRLGNALNSSLGFSKEDAASLTKIKSWSNRTKSGDVAEMPDVPESDPVWFQATSTADNCLGQDCPDYEKCFLVKARKKAQEADILVINHHLLCADWSIREIGFGELLPDAEIVIIDEAHQLADTASNFLGITVGARQLSDLAKDALVEYFKDATDLPELRTACDDLEHQIKDLRLAFGIELKRGEWREIETHPKISSGLSELQEQLQRLTVQLELASVKTKGLESCFKRAEELGHQLRAILEENDGKWIRWYETHKKTFTLSRTPIDIASEFRAFMQQHKATWIFTSATLSVANKFEHFAKSLGLANAEGVSWESPFDYAEQSLFYHPKGLPKPADPNFTRTIVEFALPVLEASRGRAFFLFTSHRALKEAESLLRPKIKYPLLVQGSRPKAILLDEFKRAGNAILLGTASFWEGVDVRGEALSCVIIDKLPFASPSDPVLKARLGAMERQGLNPFLEYQIPAAVIALRQGVGRLIRDVSDRGVLLVCDPRLLKRAYGQMFLDSVPPMRRTRDIEDVRAFFQNERNT
>NC_016112.1|WP_014149623.1|3703083_3703767_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MKLLAVDTATEACSAALYIDGEILERFELAPRTHTQLILPMIDSLMAEAGLVPQDLDGLAFGRGPGSFTGVRIATGVIQGIALGLDLPVAPVSTLAALAQNYFERAGRDVVFACMDARMGEVFWGVYRKNDQGFAELLGSESVGPAENVDFPEIKGYGIGSGWKTYREALDERLNAWLAGVDDTPLPKASAIALLGARSFNLGQAVPVEQAMPVYLRDKVAKKESER
>NC_016112.1|WP_046061636.1|3702423_3703044_-|threonylcarbamoyl-AMP-synthase
MAQFFQIHPENPQQRLINRAVEILQHGGVIAYPNDSSYAIACQMDDKQALDKIRRIRQLDDKHNFTLICQDLTQVSNFAKIDNDAYRLIKALTPGPFTFILNATREVPRRLQHPKKKTIGIRVPDHAIASLLVETIGEPLFSSTLVMPGESSALSDPYEIRDRLEHELDLVIDAGIVPDEPTTIIECSGKNLEIIRQGKGQAPMLD
>NC_016112.1|WP_014149621.1|3701751_3702408_-|site-2-protease-family-protein
MMNELSLIQRIIVWVIPVIFAITVHEAAHGWVAKKYGDNTAKMLGRLTLNPLKHIDPVGTILLPGILLLTGTGFIFGWAKPVPVDARNFKNPRQDMAVVALAGPVSNLLMAVGWALIARAGVMINVDFMTLPMIYWGIAGISINLVLALINLIPIPPLDGSRVVSGILPNRWAWQYNKLERYGFLILLLMLFTGTLNVILGYPMFLAQNMFFSLAGLG
>NC_016112.1|WP_014149620.1|3700896_3701712_-|segregation/condensation-protein-A
MQVAQAEDLPPVEEVLAIVQGAPFMKFPEDLYIPPDALRVFLDTFEGPLDLLLYLIRRQNLDILNIPIAQITRQYIGYIDMMTELRLELAAEYLVMAALLAEIKSRMLLPRQVAEEEDDEDPRALLIRRLQEYEVIKKAAEDIDGMSRLERDLFIAKADVSMIEIERPLPDIQLREMLLALQDVLKRADQLSHHHIVKEPLSVRERMSSVLERLKGGEGVIFNRLFLTQEGRHGVVVTFLAILELSKEGLIEIIQHEPLTEIVVRAVAASA
>NC_016112.1|WP_014149619.1|3699770_3700430_-|SMC-Scp-complex-subunit-ScpB
MDIKRIVEALLFASDKPMTVKQLQQTFPELEQPEIETLQKAVDEIVEDYATRPVALKKVASGYRFQVKPELSFWVGRLFEEKPPRYSRALLETLAIIAYRQPVTRGDIEDIRGVAVSSNIIRTLLEREWIRIIAHKEVPGRPALYGTTKQFLDYFDLSSLHELPTLQEIKELDLSVASNQQLMQEQSEQQENNRPEVAEQGQDTEFKAEAETFVQSTEE
>NC_016112.1|WP_014149618.1|3698911_3699751_-|pseudouridine-synthase
MKKTLTKPQDETGERIQKILARGGMGSRREIERWIEEGRVRLNGVQAKLGDRIQNGDHLQLNGRVVHWEKFAHQTTRVLIYHKPVGEVVTRQDPEGRPVVFTQLPKLQVGRWISVGRLDINTSGLLLLTNNGELANRLMHPSMQVDREYAVRILGEVSDEVFERLKQGVELDDGPAKFDDIKFHGGEGANKWYHVVVSEGRNRLVRRLWESQGVTVSRLMRVRYGLLMMPEGLKSHAFHELESKTLDVLLESVGLPKEKPLAPGKQGVKKHGFYKKNKE
>NC_016112.1|WP_014149628.1|3711896_3712514_+|ABC-transporter-substrate-binding-protein
MHNRRPLSLLFLLFCLVTTLYPLNAAANLTPPQQIIQNSSDRIQQALSQPIYHNDFAKATQFVDGVVGDFVDMERVAILVLGRHIRQATPAQRQQFIKEFRTLLVRTYTKAFQEYTDWQITFAPQISGEDPTRTIVRTIVNQPGQQPININYRMMKDRSGEWKVFDILIEGVSLVTNYRSTFNREITQTGSIDGVIKMLVDRNRR
>NC_016112.1|WP_014149629.1|3712609_3713134_+|glycine-cleavage-system-regulatory-protein
MQLAITVLGKRQSQYIEPILAAVSRCKCSIAEIRSTDLAESTAAYMLIEGNWNHIAKLENLLEVLQKQLKIHIHKARQEKSGTPKSGLPYTLEAMSLDQNDIILSIVTFLMERNIAIEEIKAYRYPAAYIQTPVFSTQLIIIIPSEQRLLQLREDFLDFCDQLNLDAILEPIKR
>NC_016112.1|WP_014149630.1|3713143_3713617_+|peroxiredoxin
MTTLSIGTAVPDFEAASTGDKTITLSDFLGKNVVIYFYPKDNTPGCTQEGIAFRDHIDEFNAFNTVILGVSRDSVKVHEGFKCKQAFPFDLLSDKDETLCNLFGVIKMKNMYGKQVRGIERSTFLIDEQGILRHEWRGVKVKNHVAEVLQELKILTQ
>NC_016112.1|WP_014149631.1|3713716_3715129_+|PhoH-family-protein
MNIQSSPKLKLFVLDTNVLMHDPAAIFRFQEHNIFIPMVVLEELDHSKRGLSEVARNVRQVSRFLDELIQGATSESIEDGFPLSRIEHAPDSDIQFGRLYFQTRQLTSMLPDSMPGHIADNSILVVVLALTQKYPDTNITLVSKDINMRIKAAALGLHAEDYHNDQTLDDIELLYRGSAALESDFWDIHGSKMESWQENDRTFYKLQGPLVSEWYPNQYLYMDNDSDFEAIVRSCDGKSAVLELAHDYRTPHNNVWGITAKNREQNFALNVLLDPEIDFVTLLGTAGTGKTLLALAAGLELTLEEKLYNEIIMTRETIPVGEDIGFLPGTEEEKMAPWMGALMDNLELLGSRSGHNEWQQGATSNLVMNRIKIRSLNFMRGRTFLNRYLIIDEAQNLTSKQMKTLITRAGPGTKIICIGNLGQIDTPYLTATTSGLTYIVDRFKTWPHAAHITLKQGERSRLADYASEIL
>NC_016112.1|WP_014149633.1|3715720_3716821_-|AI-2E-family-transporter
MTSQADFSYFDFLKNSLKRILPNSQAMALLIIILLSLVLVVSLSDFLMPVFAAVVIAYLLEGLVQKAVSLKMPRLVAVHMVFIGFIAVFGFLIFILIPMLSEQAFAFVNHLPEIIKRIQREIIRMLELYPQLLSKERVKEITLIIQEKLLSYGQDLVTMSAASLVGIMTAIVYLFLVPMMVFFFLKDKSVIVGWIGQFMPRDRLLTQNVWMEVNSQIGNYIRGKFAEIIILMSACYITFSSMNLNYAVLLSFLVGLSVIIPYVGATLVTIPVLGVAFFQWGVTTDEFMYVLIAYAVIQTLDGVVLVPLLFSEAVNLHPVAIIVAILFFGGLWGFWGVFFAIPLATVVKAVIRAWPKVGDSGLNTAF
>NC_016112.1|WP_014149634.1|3717049_3719161_-|glycogen-debranching-protein-GlgX
MDSSIALTESYCFRSGVRFPPGATPMNGGINFSVFSRHASRVELLLYKAADSPEPFQIISLDSKSHRAYFYWHVFVEELPLGTHYTWRTDGANDTAESGRRFNIRKELLDPWARAVTDAMWNRSLACDPNEAGHHSFRAVVTDSRFDWEGEQTIKRGLEGAIIYELHVGGFTKDKSSKTSHPGTFSALIEKIPYLKALGITHVELLPVMAFDEQHVPPGVQAKGLKNYWGYSTHSFYSPHPGFCITPELGTHEEEFKTLVKAMHAADIGVILDVVFNHTAEGNEEGPLINFKGLANDIFYHLDAEDRRRYLDFSGCGNSLNCNHPMVTAFIVHCLEYWVEQMHVDGFRFDLASVFARGDNGVPMDHPPLPWRIESSRLLSELPLIAEAWDAEGLYQVGAFPGMTWSEWNGRYRDVIRRFVRGDPGLIGAVATNIAGSSDLYADGDRLPVNSINFVTCHDGFTLHDWVTYEHKHNEANGEGNRDGTDDNLSWNCGVEGETFNRKINELRRQQAKNVLSLLMLSQGVPMLNAGDEVLRTQDGNNNAWCQDNEISWFDWHLVEKNSDMLRFVKELIALRRRHASLNRSSFLTGEIIPARNLPDIVWHDADLGEPAWDDEQVRFLAFMLAGLTVDEEDLYVLLNMSDHKIAAQLPPVSDRFWHLAIDTGQASPLDVVEKSDQSVWVGLACAVEARSVMVFEARSKLV
>NC_016112.1|WP_014149636.1|3719755_3721210_+|M48-family-metallopeptidase
MTKKPALFLILSLFLQGNRPFSPDITKIELPDMGDSSGTLISPAQEQQLGAAFYRSLHSQIAISQDAEIQQYIEGIGRKLVANSDTPGNPFHFFVVMDNAINAFAGPGGYIGINSGLILTSEAESELASVMAHEIAHVTQRHLYRAFEAASRLSIPTAAATLAAILIGTQSPELAQAAIMAVQAGSIQFQIDFTRDNEQEADRVGMQTLAASNFDPRSMPIFFERLQQSSRYYGRGVPEFLRTHPVTSSRISDTRGRAEKYPYQQYPDSMGYLLTRAKLRVLSANDYTPVLNYFKPRLSQGTQQQRAVARYGTGLVHLNTRNFQEAERIFKALTQEYREQPQFATAYARSALEAQNFSNALARYQAAMQQFPGNQAIKLETLSALLKSGNPEQARQILQMLDASTKRQPVYFKLLAQIYSDLKQPAESHRYLAEYYYAMGQTDAAITQIKLAQKSPGINYYLSAILNERLVFFIREEEQRKRNQ
>NC_016112.1|WP_014149637.1|3721986_3723141_-|PQQ-dependent-sugar-dehydrogenase
MKLWIIAFSYLLASCKPISDTIAKEPYLFQSDDVELEAVAIYQGKDAIWGFDFLPDGKILFTERKGRLRVFDPKTMNASDVSGVPGVAARNQGGLLDVYLHPRFSENRLVYLTYSADVGSGMTTRLARAELDADTLVNLTVLFSAEPPNNNDHHFGSRVVMSRAGNLYLSVGDRGERDQAQNMGSHYGKILRLKQDGSVPDDNPFLTEPGAKPEIWSYGHRNVQGLTIHPRTGEIWAQEHGPRGGDEINLIKKGRNYGWPVVTHGREYWGPTIGEGVEKKGMKSPIHYWVPSIAPSGLTFYNGKKIPHWQGSLFSGSLALTHLNRLVVDNHAVIKEERLLSALNKRVRAVRQGPDELLYFSTDDGSLIQIRPVDSEADSLVEEH
>NC_016112.1|WP_014149638.1|3723180_3723699_-|ATP-dependent-zinc-protease
MRIYPFALAFMMYMTTAVAEQEASVLAANMNNYTVYGHVEEVALIPGDIEIKARLDTGASKSSLNAQEIELIESDEQTMVSFIFDDRNGNRYPMTLPLVETITIKQASGRQNRYVVEMGLCVGEHYEESLFTLSDRSRMTYPVLVGRNFLKNSVLVSSKHKMTAKPTCEIGA
>NC_016112.1|WP_014149639.1|3724388_3725147_-|hypothetical-protein
MKQSMIYALDFDGVICDSAVETAITGWKAAGRLWPDMTEDRLSEQLIDRFRRVRPAIETGYEAILAMRMIDREEDDDAVLNHFEPSKQKLLDEAGVDVEFLKKLFGDTRDNWIAADLSNWISVNPLFPNVADKLKQLNEWATWYVVTTKQERFVSQILNANEIDLSGGNIFGLERNRSKADTLIEILEGHPNEQIYFVEDRLPALLSVTTNPKLQSLKLQLVDWGYNTIQDRQEAVRKGIELLCIEDFLKAK

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Crispr_ID: NC_016112_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016112_5

4283753-4285859

TypeI-E

I-E

Consensus_repeat	Method
CGGTTCATCCCCACGGGCGTGGGGAACGC	CRISPRCasFinder
CGGTTCATCCCCACGGGCGTGGGGAACGC	CRT
CGGTTCATCCCCACGGGCGTGGGGAACGC	PILER-CR
CGGTTCATCCCCACGGGCGTGGGGAACGC	PILER-CR

34 spacers

cas2,cas1,cas6e,cas5,cas7

The CRISPR arrays of NC_016112_5

>merge|NC_016112|5|4283753-4285859|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
TAATATATCCCCACAGGTGTGGGGATCGCTTGGTCTTTGTTTCTGTCTTGATGCTGAAATTGCGGTTCATCCCCACGGGCGTGGGGAACGCGCCAGGTTGTTTTGGTGCGTGCGCTGCGCTTCTGGTTCATCCCCACGGGCGTGGGGAACGCCGATTTTGAGGCTTAGGCTTGTCTTAGTATTACGGTTCATCCCCACGGGCGTGGGGAACGCATAGCTAGTCCCGGCTGGATTTCGGTCGCCGACGGTTCATCCCCACGGGCGTGGGGAACGCTTGTTGGCTTCTTCGGACGCGCGCTGTAGCACCGGTTCATCCCCACGGGCGTGGGGAACGCCTGCAGCCGCTTTCGCGCTCTCGTCATCCTGGCGGTTCATCCCCACGGGCGTGGGGAACGCGTCATGTTCGCGAACGAACAAGGCCCCTTTTCCCGGTTCATCCCCACGGGCGTGGGGAACGCACGCGAGGTGCTCGAATGAAAGGCGTTGGGTCCGGTTCATCCCCACGGGCGTGGGGAACGCCACTAATACTGATTTCGGCAATTTGATCGGGACGGTTCATCCCCACGGGCGTGGGGAACGCAAGTTGCGTCTGATCATTTGGGTGCCGACGAGCGGTTCATCCCCACGGGGGGGGGGGAACGCACTAACTCAGTCGTAGCCCTGGAAATAACCTGCGGTTCATCCCCACGGGCGTGGGGAACGCGCCAGCGCGCGGAAAACAAAAACGCACGATCGCGGTTCATCCCCACGGGCGTGGGGAACGCTTAATAATAGAAATGGCCCGCGTCCGTGAAATACGGTTCATCCCCACGGGCGTGGGGAACGCTGCTAAAAACAGAAGCTGAAAACCGAAAAGAACGGTTCATCCCCACGGGCGTGGGGAACGCCGTCCAGAACCGATCGCACGACCGCAGCCGGACGGTTCATCCCCACGGGCGTGGGGAACGCTTGGCTACGGGCATAACCTAGACTCAAAGCCACGGTTCATCCCCACGGGCGTGGGGAACGCCTCAGCGGTCGAATCCCAAGACTGGTATCAAGCGGTTCATCCCCACGGGCGTGGGGAACGCCTTGCTAGTGTCCTCGACCGCGTCCGCCAACGCGGTTCATCCCCACGGGCGTGGGGAACGCTTCCTCTTGTGCGGCCGGATTTGCCGGGATGACGGTTCATCCCCACGGGCGTGGGGAACGCTTCTGCAAATACTCCAACCGCTCCAACAACCGCGGTTCATCCCCACGGGCGTGGGGAACGCAAGAATGGTACTACATCGATCAAGCGGTAAGGCGGTTCATCCCCACGGGCGTGGGGAACGCGCGACCAATGCCGTCTAAATACCAATCCCCACCGGTTCATCCCCACGGGCGTGGGGAACGCAAATCAAACGCACATGAATTCGTCATTTACAACGGTTCATCCCCACGGGCGTGGGGAACGCGGAGATGAACCGCAAGAGCAAGGCGCTGGACCTGGTTCATCCCCACGGGCGTGGGGAACGCTTTTTATAATGTTTGTTCATGATTCGGTTTGTCGGTTCATCCCCACGGGCGTGGGGAACGCGATAGCGATTAACACTGCATTGAGCGCTGCCGCGGTTCATCCCCACGGGCGTGGGGAACGCGACGACGGGTATCGAGCGGACGAATGCGTATACGGTTCATCCCCACGGGCGTGGGGAACGCTCTGTATGCCGGTATATTTTCGGGGATAACAACGGTTCATCCCCACGGGCGTGGGGAACGCCGTGTACTTTCAGCCGTATCTGATGCAAATGGCGGTTCATCCCCACGGGCGTGGGGAACGCGTGGTGTCGTCCAGATCAACATACCAAAGTAGCGGTTCATCCCCACGGGCGTGGGGAACGCTAGGAAAGCGGCACCCATGCCCACAATAGCAGCGGTTCATCCCCACGGGCGTGGGGAACGCCGCTGATGTTCAATCCAGTCGAGGCGTTGATCCGGTTCATCCCCACGGGCGTGGGGAACGCCCCCAACAGCATGCCAAGCCCTTCTTGAGAAGCGGTTCATCCCCACGGGCGTGGGGAACGCTTGACACCCGTACCGGCAGCAAAGGCCGTATCTGGTTCATCCCCACGGGCGTGGGGAACGC

>NC_016112|5|5|4283753-4285859|CRISPRCasFinder
TAATATATCCCCACAGGTGTGGGGATCGC	TTGGTCTTTGTTTCTGTCTTGATGCTGAAATTG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCCAGGTTGTTTTGGTGCGTGCGCTGCGCTTC
TGGTTCATCCCCACGGGCGTGGGGAACGC	CGATTTTGAGGCTTAGGCTTGTCTTAGTATTA
CGGTTCATCCCCACGGGCGTGGGGAACGC	ATAGCTAGTCCCGGCTGGATTTCGGTCGCCGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGTTGGCTTCTTCGGACGCGCGCTGTAGCAC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTGCAGCCGCTTTCGCGCTCTCGTCATCCTGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GTCATGTTCGCGAACGAACAAGGCCCCTTTTCC
CGGTTCATCCCCACGGGCGTGGGGAACGC	ACGCGAGGTGCTCGAATGAAAGGCGTTGGGTC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CACTAATACTGATTTCGGCAATTTGATCGGGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAGTTGCGTCTGATCATTTGGGTGCCGACGAG
CGGTTCATCCCCACGGGGGGGGGGGAACG	CACTAACTCAGTCGTAGCCCTGGAAATAACCTG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCCAGCGCGCGGAAAACAAAAACGCACGATCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTAATAATAGAAATGGCCCGCGTCCGTGAAATA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TGCTAAAAACAGAAGCTGAAAACCGAAAAGAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGTCCAGAACCGATCGCACGACCGCAGCCGGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGGCTACGGGCATAACCTAGACTCAAAGCCA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTCAGCGGTCGAATCCCAAGACTGGTATCAAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTTGCTAGTGTCCTCGACCGCGTCCGCCAACG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTCCTCTTGTGCGGCCGGATTTGCCGGGATGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTCTGCAAATACTCCAACCGCTCCAACAACCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAGAATGGTACTACATCGATCAAGCGGTAAGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCGACCAATGCCGTCTAAATACCAATCCCCAC
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAATCAAACGCACATGAATTCGTCATTTACAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	GGAGATGAACCGCAAGAGCAAGGCGCTGGACC
TGGTTCATCCCCACGGGCGTGGGGAACGC	TTTTTATAATGTTTGTTCATGATTCGGTTTGT
CGGTTCATCCCCACGGGCGTGGGGAACGC	GATAGCGATTAACACTGCATTGAGCGCTGCCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GACGACGGGTATCGAGCGGACGAATGCGTATA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TCTGTATGCCGGTATATTTTCGGGGATAACAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGTGTACTTTCAGCCGTATCTGATGCAAATGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GTGGTGTCGTCCAGATCAACATACCAAAGTAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TAGGAAAGCGGCACCCATGCCCACAATAGCAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGCTGATGTTCAATCCAGTCGAGGCGTTGATC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CCCCAACAGCATGCCAAGCCCTTCTTGAGAAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGACACCCGTACCGGCAGCAAAGGCCGTATC
TGGTTCATCCCCACGGGCGTGGGGAACGC

>NC_016112|5|3|4283753-4285859|CRT
TAATATATCCCCACAGGTGTGGGGATCGC	TTGGTCTTTGTTTCTGTCTTGATGCTGAAATTG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCCAGGTTGTTTTGGTGCGTGCGCTGCGCTTC
TGGTTCATCCCCACGGGCGTGGGGAACGC	CGATTTTGAGGCTTAGGCTTGTCTTAGTATTA
CGGTTCATCCCCACGGGCGTGGGGAACGC	ATAGCTAGTCCCGGCTGGATTTCGGTCGCCGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGTTGGCTTCTTCGGACGCGCGCTGTAGCAC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTGCAGCCGCTTTCGCGCTCTCGTCATCCTGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GTCATGTTCGCGAACGAACAAGGCCCCTTTTCC
CGGTTCATCCCCACGGGCGTGGGGAACGC	ACGCGAGGTGCTCGAATGAAAGGCGTTGGGTC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CACTAATACTGATTTCGGCAATTTGATCGGGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAGTTGCGTCTGATCATTTGGGTGCCGACGAG
CGGTTCATCCCCACGGGGGGGGGGGAACG	CACTAACTCAGTCGTAGCCCTGGAAATAACCTG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCCAGCGCGCGGAAAACAAAAACGCACGATCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTAATAATAGAAATGGCCCGCGTCCGTGAAATA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TGCTAAAAACAGAAGCTGAAAACCGAAAAGAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGTCCAGAACCGATCGCACGACCGCAGCCGGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGGCTACGGGCATAACCTAGACTCAAAGCCA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTCAGCGGTCGAATCCCAAGACTGGTATCAAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTTGCTAGTGTCCTCGACCGCGTCCGCCAACG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTCCTCTTGTGCGGCCGGATTTGCCGGGATGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTCTGCAAATACTCCAACCGCTCCAACAACCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAGAATGGTACTACATCGATCAAGCGGTAAGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCGACCAATGCCGTCTAAATACCAATCCCCAC
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAATCAAACGCACATGAATTCGTCATTTACAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	GGAGATGAACCGCAAGAGCAAGGCGCTGGACC
TGGTTCATCCCCACGGGCGTGGGGAACGC	TTTTTATAATGTTTGTTCATGATTCGGTTTGT
CGGTTCATCCCCACGGGCGTGGGGAACGC	GATAGCGATTAACACTGCATTGAGCGCTGCCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GACGACGGGTATCGAGCGGACGAATGCGTATA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TCTGTATGCCGGTATATTTTCGGGGATAACAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGTGTACTTTCAGCCGTATCTGATGCAAATGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GTGGTGTCGTCCAGATCAACATACCAAAGTAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TAGGAAAGCGGCACCCATGCCCACAATAGCAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGCTGATGTTCAATCCAGTCGAGGCGTTGATC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CCCCAACAGCATGCCAAGCCCTTCTTGAGAAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGACACCCGTACCGGCAGCAAAGGCCGTATC
TGGTTCATCCCCACGGGCGTGGGGAACGC

>NC_016112|5|4|4283815-4284271|PILER-CR
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCCAGGTTGTTTTGGTGCGTGCGCTGCGCTTC
TGGTTCATCCCCACGGGCGTGGGGAACGC	CGATTTTGAGGCTTAGGCTTGTCTTAGTATTA
CGGTTCATCCCCACGGGCGTGGGGAACGC	ATAGCTAGTCCCGGCTGGATTTCGGTCGCCGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGTTGGCTTCTTCGGACGCGCGCTGTAGCAC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTGCAGCCGCTTTCGCGCTCTCGTCATCCTGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GTCATGTTCGCGAACGAACAAGGCCCCTTTTCC
CGGTTCATCCCCACGGGCGTGGGGAACGC	ACGCGAGGTGCTCGAATGAAAGGCGTTGGGTC
CGGTTCATCCCCACGGGCGTGGGGAACGCCACTAATACTGATTTCGGCAATTTGATCGGGACGGTTCATCCCCACGGGCGTGGGGAACGCAAGTTGCGTCTGATCATTTGGGTGCCGACGAGCGGTTCATCCCCACGGGGGGGGGGGAACGCACTAACTCAGTCGTAGCCCTGGAAATAACCTGCGGTTCATCCCCACGGGCGTGGGGAACGC	GCCAGCGCGCGGAAAACAAAAACGCACGATCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTAATAATAGAAATGGCCCGCGTCCGTGAAATA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TGCTAAAAACAGAAGCTGAAAACCGAAAAGAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGTCCAGAACCGATCGCACGACCGCAGCCGGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGGCTACGGGCATAACCTAGACTCAAAGCCA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTCAGCGGTCGAATCCCAAGACTGGTATCAAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTTGCTAGTGTCCTCGACCGCGTCCGCCAACG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTCCTCTTGTGCGGCCGGATTTGCCGGGATGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTCTGCAAATACTCCAACCGCTCCAACAACCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAGAATGGTACTACATCGATCAAGCGGTAAGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCGACCAATGCCGTCTAAATACCAATCCCCAC
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAATCAAACGCACATGAATTCGTCATTTACAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	GGAGATGAACCGCAAGAGCAAGGCGCTGGACC
TGGTTCATCCCCACGGGCGTGGGGAACGC	TTTTTATAATGTTTGTTCATGATTCGGTTTGT
CGGTTCATCCCCACGGGCGTGGGGAACGC	GATAGCGATTAACACTGCATTGAGCGCTGCCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GACGACGGGTATCGAGCGGACGAATGCGTATA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TCTGTATGCCGGTATATTTTCGGGGATAACAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGTGTACTTTCAGCCGTATCTGATGCAAATGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GTGGTGTCGTCCAGATCAACATACCAAAGTAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TAGGAAAGCGGCACCCATGCCCACAATAGCAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGCTGATGTTCAATCCAGTCGAGGCGTTGATC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CCCCAACAGCATGCCAAGCCCTTCTTGAGAAG


>NC_016112|5|5|4284427-4285798|PILER-CR
	GCCAGGTTGTTTTGGTGCGTGCGCTGCGCTTC
TGGTTCATCCCCACGGGCGTGGGGAACGC	CGATTTTGAGGCTTAGGCTTGTCTTAGTATTA
CGGTTCATCCCCACGGGCGTGGGGAACGC	ATAGCTAGTCCCGGCTGGATTTCGGTCGCCGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGTTGGCTTCTTCGGACGCGCGCTGTAGCAC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTGCAGCCGCTTTCGCGCTCTCGTCATCCTGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GTCATGTTCGCGAACGAACAAGGCCCCTTTTCC
CGGTTCATCCCCACGGGCGTGGGGAACGC	ACGCGAGGTGCTCGAATGAAAGGCGTTGGGTC
CGGTTCATCCCCACGGGCGTGGGGAACGCCACTAATACTGATTTCGGCAATTTGATCGGGACGGTTCATCCCCACGGGCGTGGGGAACGCAAGTTGCGTCTGATCATTTGGGTGCCGACGAGCGGTTCATCCCCACGGGGGGGGGGGAACGCACTAACTCAGTCGTAGCCCTGGAAATAACCTGCGGTTCATCCCCACGGGCGTGGGGAACGC	GCCAGCGCGCGGAAAACAAAAACGCACGATCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTAATAATAGAAATGGCCCGCGTCCGTGAAATA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TGCTAAAAACAGAAGCTGAAAACCGAAAAGAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGTCCAGAACCGATCGCACGACCGCAGCCGGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTGGCTACGGGCATAACCTAGACTCAAAGCCA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTCAGCGGTCGAATCCCAAGACTGGTATCAAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	CTTGCTAGTGTCCTCGACCGCGTCCGCCAACG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTCCTCTTGTGCGGCCGGATTTGCCGGGATGA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TTCTGCAAATACTCCAACCGCTCCAACAACCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAGAATGGTACTACATCGATCAAGCGGTAAGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GCGACCAATGCCGTCTAAATACCAATCCCCAC
CGGTTCATCCCCACGGGCGTGGGGAACGC	AAATCAAACGCACATGAATTCGTCATTTACAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	GGAGATGAACCGCAAGAGCAAGGCGCTGGACC
TGGTTCATCCCCACGGGCGTGGGGAACGC	TTTTTATAATGTTTGTTCATGATTCGGTTTGT
CGGTTCATCCCCACGGGCGTGGGGAACGC	GATAGCGATTAACACTGCATTGAGCGCTGCCG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GACGACGGGTATCGAGCGGACGAATGCGTATA
CGGTTCATCCCCACGGGCGTGGGGAACGC	TCTGTATGCCGGTATATTTTCGGGGATAACAA
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGTGTACTTTCAGCCGTATCTGATGCAAATGG
CGGTTCATCCCCACGGGCGTGGGGAACGC	GTGGTGTCGTCCAGATCAACATACCAAAGTAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	TAGGAAAGCGGCACCCATGCCCACAATAGCAG
CGGTTCATCCCCACGGGCGTGGGGAACGC	CGCTGATGTTCAATCCAGTCGAGGCGTTGATC
CGGTTCATCCCCACGGGCGTGGGGAACGC	CCCCAACAGCATGCCAAGCCCTTCTTGAGAAG
CGGTTCATCCCCACGGGCGTGGGGAACGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016112.1\|WP_014150127.1\|4290992_4292243_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NC_016112.1\|WP_068794399.1\|4277657_4278224_+\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014150125.1\|4289689_4290310_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09727_cas6e_CAS-I-E	gnl\|CDD\|378050
NC_016112.1\|WP_014150117.1\|4286409_4287321_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_016112.1\|WP_014150107.1\|4270020_4271739_+\|retention-module-containing-protein	unknown	unknown	gnl\|CDD\|380149
NC_016112.1\|WP_014146713.1\|4271759_4272506_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|181681
NC_016112.1\|WP_046061244.1\|4288541_4288973_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|350263
NC_016112.1\|WP_014150120.1\|4288016_4288292_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NC_016112.1\|WP_014150126.1\|4290296_4290989_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
NC_016112.1\|WP_014150118.1\|4287324_4287627_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368240
NC_016112.1\|WP_014150115.1\|4282859_4283642_-\|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl\|CDD\|378959
NC_016112.1\|WP_026130291.1\|4287627_4287897_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NC_016112.1\|WP_014150114.1\|4281299_4282766_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|226428
NC_016112.1\|WP_014150112.1\|4278410_4280252_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271199
NC_016112.1\|WP_014150109.1\|4272492_4274052_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NC_016112.1\|WP_014150116.1\|4285974_4286277_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|236930
NC_016112.1\|WP_014150110.1\|4274471_4277423_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380149
NC_016112.1\|WP_176564468.1\|4274176_4274323_-\|hypothetical-protein	unknown	unknown	unknown
NC_016112.1\|WP_014150113.1\|4280416_4280935_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|226975
NC_016112.1\|WP_014150123.1\|4288950_4289208_-\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|289422

Protein	Function_ID	Function_description	E-value
NC_016112.1\|WP_014150127.1\|4290992_4292243_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.63043e-127
NC_016112.1\|WP_014150125.1\|4289689_4290310_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	3.94906e-56
NC_016112.1\|WP_014150117.1\|4286409_4287321_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.74562e-151
NC_016112.1\|WP_014150107.1\|4270020_4271739_+\|retention-module-containing-protein	gnl\|CDD\|380149	NF012181, MSCRAMM_SdrD, MSCRAMM family adhesin SdrD. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	7.24309e-21
NC_016112.1\|WP_014146713.1\|4271759_4272506_-\|ATP-binding-protein	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	6.35141e-67
NC_016112.1\|WP_046061244.1\|4288541_4288973_-\|DNA-binding-protein	gnl\|CDD\|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	8.81998e-32
NC_016112.1\|WP_014150120.1\|4288016_4288292_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	2.54789e-13
NC_016112.1\|WP_014150126.1\|4290296_4290989_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	1.26249e-46
NC_016112.1\|WP_014150118.1\|4287324_4287627_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	1.81582e-08
NC_016112.1\|WP_014150115.1\|4282859_4283642_-\|Bax-inhibitor-1/YccA-family-protein	gnl\|CDD\|378959	pfam12811, BaxI_1, Bax inhibitor 1 like. The Bax-inhibitor-1 region of the receptor molecules is conserved from bacteria to humans.	1.11192e-57
NC_016112.1\|WP_026130291.1\|4287627_4287897_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	1.65834e-11
NC_016112.1\|WP_014150114.1\|4281299_4282766_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|226428	COG3914, Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones].	4.99461e-93
NC_016112.1\|WP_014150112.1\|4278410_4280252_+\|hypothetical-protein	gnl\|CDD\|271199	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.	2.36429e-06
NC_016112.1\|WP_014150109.1\|4272492_4274052_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.07438e-24
NC_016112.1\|WP_014150116.1\|4285974_4286277_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.7927e-60
NC_016112.1\|WP_014150110.1\|4274471_4277423_+\|hypothetical-protein	gnl\|CDD\|380149	NF012181, MSCRAMM_SdrD, MSCRAMM family adhesin SdrD. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	6.19286e-18
NC_016112.1\|WP_014150113.1\|4280416_4280935_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|226975	COG4627, COG4627, Uncharacterized protein conserved in bacteria [Function unknown].	7.69825e-29
NC_016112.1\|WP_014150123.1\|4288950_4289208_-\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|289422	pfam12651, RHH_3, Ribbon-helix-helix domain. This short bacterial protein contains a ribbon-helix-helix domain that is likely to be DNA-binding.	0.00585418

>NC_016112.1|WP_014150115.1|4282859_4283642_-|Bax-inhibitor-1/YccA-family-protein
MALPRTLGLGSPLLNLPRSFKPISSPTEQPVFRLSLRQQMFSLGLLFTLSLLAALAMAAYFYPSIASNDKVVANIVRNIGFGGGVFGFSLVLLTAFYRHWASVTAPLYALAGGVFMSGLALSLEQRFPGIAVQSLVVTFSIALVMYALYATGVIKVTRKLFVLIYAATATIALVYLVGFTALLAGVPLPFLHGAGVGGMLWFGFIVVTASLNLLVDFRRIDNAIQRAQPSWMRWYLGLGMLVTLVWMYISVLRLIANARR
>NC_016112.1|WP_014150114.1|4281299_4282766_+|tetratricopeptide-repeat-protein
MSDSFKNVFAQGVAAFEQGNYDEAAAFLKEAKSMNTDDSRVFRVLGNCLRLLGKVDEAISVYREGLQIKYDLNTHQRLINTLNYSDEPPSLVALEHKKWAEAYTNHYVLKYKLSLKPRSKHLKIRIGYVSPDFNAHPVAYFLLPIIQNHNKDIFEIFCYANINQEDGVTHQFKLAADRWIDIRHMSTVQLFDQIQQDAIDILIDVAGLTSGNRLDVFALRAAPVQVTYLGYPGTTGLKTMDYRLVDSISDPQNVSDEWHSEKLYRLPDCFLCFRLPPENLKINDAPCQSKSFVTFGTFNKISKITDRTIALWVQILQAVPDSKFVLKGRGFEKKVEQNRIKKRFASAGLEQIDRLVLYGFSPKRSEHLLLYNELDIALDTFPYNGTTTTMQAIFMGVPVIALDGKSHVARVSQSILSAIGANELVAMDEEDYFLKAVHLANDKERIAHYKKELRSMLEDSPIRNEMNFIANLEEAYRRMLREKQLRIW
>NC_016112.1|WP_014150113.1|4280416_4280935_+|methyltransferase-domain-containing-protein
MASKLHIGGTKRKAGWEIFNIVKTDHVDHVGNANDLSRFADNTFSAIYASHILEHFSYISDLQEVLKEWFRVLLPGGKIYLSVPDLDTLATLLVDKSLSFKDRFYVMRMLYGGQTNAYDFHMVGLNEDFLRFYLTKAGFKSITRVERFGIFNDTSNKQFLNRPISLNMTALK
>NC_016112.1|WP_014150112.1|4278410_4280252_+|hypothetical-protein
MADQNRAFHSKTDFSAEHRLLNDIRQALISGESAFSTTDLDLPFDPAISQIYISLFQRGLKSIRWGARRATIEATLQRIVEKLKTNPALSDFAVQDANQCRILFEMVTEERPCPLKSLTGSTFCDSRFEPGITGIKYEFKGVLRYFMPTDAVVHSIMSVSQLLRFLAKKTGIAKQSNRFSVREKLMRSEPISSSLIKSIAFISYTDREILPLYRGYPISKVRFDKETLLESTLKSIDWLVANMNDDGSFLYFYDAYQDTKVDFDHPKMADPLYNNILRHCGGTISLLRGYELTGRNDYLEAAGHSMQYLFSTLREHEWQGRYACYPFDNKKSKLGGAGVALVALMHYYRHTGDEAYRLTIDGLVRHILSRIADDGEMIGYYIHPLFNQGQPIIDPPDDIKRQLFSFYYPGEALLGLALYYQWIDRIDDDLKKEIAEKSEKALDFLVDIRPVKYKELFLELPADAWLMQATEEWVKVEGFRKNSYIDFVFNDANAMIEHSYTDENSPYLDYAGGFYYYYGDHVYHDGSRCEGLIAAYYLSTYLGEQKRADKIMAAMIASAKGLMYTRHTAESTYAHLYPEKSINSFRFKLTRQWVRVDSVQHTACFYSRLYFVM
>NC_016112.1|WP_068794399.1|4277657_4278224_+|hypothetical-protein
MLLIFMVIMPAKAALISDFTGPYSLNNWTETIGGNGAIDLDGFSSVTLTGSDRETPLDYPNESPIVVDFTIEAVASGFVSFQWFYETLDKDEWFGGSQWDPFGYLLNDVFFQLTDDNGAFEQTGQTHFFVNAGDIFGFRQKTIDDQFGAGITTISQFSVQVPEPHISFLLSLGLACFLLTYSRRLKRS
>NC_016112.1|WP_014150110.1|4274471_4277423_+|hypothetical-protein
MDTDTDTDTDSDTDSDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDLDTDTDTDTDSDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDSDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDLDTDTDTDTDTDTDTDTDTDTDLDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDSDTDTDSDTDTDTDTDTDTDTDTDTDTDSDTDTDTDLDTDTDTDTDTDTDTDTDTDTDTDTDTDTDSDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDLDTDTDTDTDTDTDTDTDTDTDTDSDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDSDTDTDTDTDSDTDTDTDTDTDSDTDTDTDTDTDTDTDTDTDTDTDTDTDTDTDDDCEIPHAISYIAFKLEGRTGGVIKVEFPSSPEFTNVAIAVSLAEFIENNNGSNVLDIIIKAGPGHYDQTGQSTTTDGWTTNPGGLVIGRTYSLQDFIDQGFEADPDSSCITEYAAVSMSAETITTYEFDEENIVNAEETSFEEEFSDEEIDTSTEDEDSTEEKEESTDDEDVTEDEQSDEVDQDLSDGEDTTDNEEPDNSDHTPDDHEPDQDEESKMPEEGSTSDETDESAKTQNVINNEEPDNGDEEDSDQDNNGNRQGNNGHGNGDQDAPANSGDNNNAENSDNSGQGNSGGNRQGNNGHGNGDQDAPGNSEDNNNAENSNNFDQGNSGKTLSLEDLLDDGDDLFMSDNDPRTSGADMDDPLNPFENGFDLPDSLEPDPE
>NC_016112.1|WP_176564468.1|4274176_4274323_-|hypothetical-protein
MSESVSVSVSVSVSVSVSVSVSVSESVSVSVSVSVSVSVSVSVSVSEC
>NC_016112.1|WP_014150109.1|4272492_4274052_-|IS21-family-transposase
MIHQIKALYNDGNGLSERQIASQLGISRNTVSKYLKLSAADISALQEEISRGKKLDDYRDYIIQLLQTYPGLSAVKVLRKLKAKVDDLAVSDRSVRRYIQALKQEISFKQARYYEPVLDMVPGEQCQVDGGELRDVMIGGVATTVYFIVFVLSYSRLMHVSICAKPIDTEMLIRQHDAAFRYFGGMPQECVYDQTKLVVISEVFRELRLNQRFHQYATAAGFTIRACEGYDPESKGKVEAGVKYVKQNALYGETFTDWDALKAHMTDWLDGIANQRRHGTTGQQPAIHYAANEQGHMRAYLTPSCVDATASQARITRKADKTGLIAWQSNKYSVPMAYQCARVAVHEANGVIQISDLSTHKVIAEHAVCLEKGQIIKNRHHYRDMSLRIETLEKDLHELLPSPAVVTQLCALLKASSPKIYKDQLAGAKQVLTEQIKQQGAIPEAVLTRLIDTPRLTASGLKERLEAWRQSVGRSDDSDALSMPPSEQATAAIKQECPLARYRALNGHSAGQGESHAIH
>NC_016112.1|WP_014146713.1|4271759_4272506_-|ATP-binding-protein
MPSIDQIARQYRSLCLTAIAEHLPTLLGQAETHESSYLQFAESLVEHEQRQRNAKRIEQNRKRAGFPLLKSLEEFDYRFQTTISKREVNSLLDFGFIDNRDNVVFIGPPGVGKTHLAIGIGLKAIDAGYKVSFNTALGLMEVLELAELKGELKKKINQLLKFDVLIIDELGYLPMNKQGMHNLFQLINALYEYRSVILTTNKEFTNWGEFFIDDNVAVPIVDRIIHHSHIFMLGGESYRLKSKLNQAS
>NC_016112.1|WP_014150107.1|4270020_4271739_+|retention-module-containing-protein
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
>NC_016112.1|WP_014150116.1|4285974_4286277_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MLVIVVENVPPRLRGRLAVWLIEIRAGVYVGDLSVKVREMIWQQIEAGIEDGNAVMVWSTNTESGFDFMTLGKNRRLPVELDGLKLVSFYPIEDDEAKAL
>NC_016112.1|WP_014150117.1|4286409_4287321_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MLPPLKPIAMKERVSMVFIQKGQIDVKDGAFVVIDETGIRTHIPVGSIACIMLEPGTRISHHAAALAARAGTLLVWVGDAGVRLYASGQPGGARSDRLLYQAKLALDDTARLKVVRKMYEIRFGEKPPERRSVEQLRGIEGARVKKTYQLLAKQVGVEWKGRKYDPSQWDKSDMPNRCISSATACLYGICEAAVLAAGYAPAIGFIHTGKPLSFVYDIADLFKFDDIIPHAFKIAAKNYHDPEREVRLMCRDIFRQTKILKKIIPTIEDVLAAGELEIPKPAEENIEPAIPNPENIGDVGHRS
>NC_016112.1|WP_014150118.1|4287324_4287627_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKLLFADSAINDLMDIKTYYREQGIEHIGEKFVSGIIAHLEVLIKHPEIGRIVPEFAEPKIRELIHPPFRVVYWLDNPQIHVVRVWRSERLLQLPDLNQS
>NC_016112.1|WP_026130291.1|4287627_4287897_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MQTKFSEDVISLSDLKINPAKVINQVKDTHRPILLTSRGRGVAVVQNLDDYEKDQEERAFMKAVAQGLMDVKNGRVMELAEVKTKLAID
>NC_016112.1|WP_014150120.1|4288016_4288292_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MKLSENIKPISYLKANAAEVIEKLKTDHQPPVITQNGEAAMVIQSVADYEQTQETLALLKLLTQSQQAAVEGKTVSSQEAFARLRQRRGLI
>NC_016112.1|WP_046061244.1|4288541_4288973_-|DNA-binding-protein
MKNWVIADTGFWYALLNKDDSYHLKAVDMLGRIDAGLVSTWPVITETSYFLQSRLGQNQACAFLSTYDEGLFDIYELRPAHLKRMIVLMQKYADLPMDLADASLVILAEELGHGRILSTDMRDFQTYRWKNRKPFQNLLFPDS
>NC_016112.1|WP_014150123.1|4288950_4289208_-|ribbon-helix-helix-protein,-CopG-family
MRITARIDEDYEQKLKAIQRKTNLNTTEIIKIALDLLYEKTELSGAEKNRMLIDKLAGIGHGPSDGSVRYKEYVAEYIDEKLGHR
>NC_016112.1|WP_014150125.1|4289689_4290310_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSKVFIDFKKPKNIYQIHQDLWKLFPGQDDKVRSFLFRVEQQQVGVGASILMQSEIAPSVGNKQVNLLATRELPLIIIKNQRLRFLLVANPVRTIKDEQERKNKKGEIKSNRVPLIKDEDRQNWLERKLQSWAQLDSLVIRPCPPLYFYKKDEENPKGHSGKIVPVTFEGVLIVQEPDKFIGQVQQGIGPAKAFGCGLLSVAKV
>NC_016112.1|WP_014150126.1|4290296_4290989_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MQDYLIIKLQGAMQAWGGHTYEDYRPSLIFPTRSAIVGLLGACLGIEREEIKSLKKLDKSFQLTVRVNKRKIAQRKGAEDKLVSMQKITDFHTVQHARKVDGKARPEAIVSRREYLCDAEFTVALAFSENTDYDLERIKQAIKKPVYTPFLGRRSCPIQSPLYETVVSAHNVQAALSLIEPYQGTLYSEIALDGGTPMMVRDQPLFATNVRQFNNRKIYILGSGDKYVPE
>NC_016112.1|WP_014150127.1|4290992_4292243_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSDKNFVNYHILISHNSSCLNRDDMGMQKTAVFGGTRRVRISSQSLKREMRKPRLQEHSNNYWQQNLGEPSIRTRDLSKLNEKFIEELSDEFEPAFVSEAIDRFVKTAKATAGEADASDNGDDPAEKGAAKKASKKIAVAPWVSNEIREICRVIKAVKNEGLSADEMKKIEDTKKKKENLEDLIEKAINKKIEKQLKEKAEAINNALASAVDIALFGRMTTDGLMSKVDGAMAVAHAITTHTVDGDIDWFTAVDDLIQDSGETGSGHLDTQEFSAGVFYRYASLNLSLLQKNLGVDRARALEIAKHFLHLLATTIPSAKQNSFAAFNLTDFACVSLSDMPISLANAFEEPVARGQKGGFRKPSIDAFCEYKQKTDDIYGFKDMTVFFSSENCALPSTQRMKTLAELEQWLQNDGKV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_016112_4	4.1\|3711383\|26\|NC_016112\|CRISPRCasFinder	3711383-3711408	26	NC_016112.1	429885-429910	0	1.0
NC_016112_4	4.1\|3711383\|26\|NC_016112\|CRISPRCasFinder	3711383-3711408	26	NC_016112.1	2837175-2837200	0	1.0
NC_016112_4	4.1\|3711383\|26\|NC_016112\|CRISPRCasFinder	3711383-3711408	26	NC_016112.1	2837224-2837249	0	1.0
NC_016112_4	4.1\|3711383\|26\|NC_016112\|CRISPRCasFinder	3711383-3711408	26	NC_016112.1	3393894-3393919	0	1.0
NC_016112_4	4.1\|3711383\|26\|NC_016112\|CRISPRCasFinder	3711383-3711408	26	NC_016112.1	75039-75064	1	0.962
NC_016112_4	4.1\|3711383\|26\|NC_016112\|CRISPRCasFinder	3711383-3711408	26	NC_016112.1	3895993-3896018	1	0.962

1. spacer 4.1|3711383|26|NC_016112|CRISPRCasFinder matches to position: 429885-429910, mismatch: 0, identity: 1.0

tttgcagatttttgctcctgcaaaat	CRISPR spacer
tttgcagatttttgctcctgcaaaat	Protospacer
**************************

2. spacer 4.1|3711383|26|NC_016112|CRISPRCasFinder matches to position: 2837175-2837200, mismatch: 0, identity: 1.0

tttgcagatttttgctcctgcaaaat	CRISPR spacer
tttgcagatttttgctcctgcaaaat	Protospacer
**************************

3. spacer 4.1|3711383|26|NC_016112|CRISPRCasFinder matches to position: 2837224-2837249, mismatch: 0, identity: 1.0

tttgcagatttttgctcctgcaaaat	CRISPR spacer
tttgcagatttttgctcctgcaaaat	Protospacer
**************************

4. spacer 4.1|3711383|26|NC_016112|CRISPRCasFinder matches to position: 3393894-3393919, mismatch: 0, identity: 1.0

tttgcagatttttgctcctgcaaaat	CRISPR spacer
tttgcagatttttgctcctgcaaaat	Protospacer
**************************

5. spacer 4.1|3711383|26|NC_016112|CRISPRCasFinder matches to position: 75039-75064, mismatch: 1, identity: 0.962

tttgcagatttttgctcctgcaaaat	CRISPR spacer
tttgcagatttttgctcctgcacaat	Protospacer
********************** ***

6. spacer 4.1|3711383|26|NC_016112|CRISPRCasFinder matches to position: 3895993-3896018, mismatch: 1, identity: 0.962

tttgcagatttttgctcctgcaaaat	CRISPR spacer
tttgcagatttttgctccagcaaaat	Protospacer
****************** *******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_016112_4	4.1\|3711383\|26\|NC_016112\|CRISPRCasFinder	3711383-3711408	26	MN693855	Marine virus AFVG_250M616, complete genome	13191-13216	4	0.846
NC_016112_4	4.1\|3711383\|26\|NC_016112\|CRISPRCasFinder	3711383-3711408	26	NZ_CP024167	Salmonella enterica subsp. enterica serovar Gaminara strain CFSAN070644 plasmid pCFSAN024441_02, complete sequence	37652-37677	4	0.846
NC_016112_5	5.25\|4285250\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285250-4285281	32	NZ_CP029460	Clostridium novyi strain 150557 plasmid pCN2, complete sequence	21488-21519	5	0.844
NC_016112_2	2.2\|1516573\|34\|NC_016112\|PILER-CR,CRISPRCasFinder,CRT	1516573-1516606	34	MK241539	Alteromonas phage P24, complete genome	26467-26500	6	0.824
NC_016112_2	2.43\|1519516\|35\|NC_016112\|PILER-CR	1519516-1519550	35	NZ_CP050100	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b3, complete sequence	217297-217331	6	0.829
NC_016112_2	2.71\|1519512\|35\|NC_016112\|CRISPRCasFinder,CRT	1519512-1519546	35	NZ_CP050100	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b3, complete sequence	217297-217331	6	0.829
NC_016112_5	5.15\|4284640\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284640-4284671	32	NZ_CP014803	Salipiger profundus strain JLT2016 plasmid pTPRO7, complete sequence	59066-59097	6	0.812
NC_016112_5	5.23\|4285128\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285128-4285159	32	MN693592	Marine virus AFVG_25M471, complete genome	2461-2492	6	0.812
NC_016112_5	5.23\|4285128\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285128-4285159	32	MN693131	Marine virus AFVG_25M472, complete genome	2460-2491	6	0.812
NC_016112_3	3.26\|2436751\|33\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	2436751-2436783	33	NZ_CP025432	Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence	168189-168221	7	0.788
NC_016112_3	3.28\|2436880\|33\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	2436880-2436912	33	NZ_CP011481	Hoeflea sp. IMCC20628 plasmid, complete sequence	6155-6187	7	0.788
NC_016112_5	5.6\|4284088\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284088-4284119	32	NZ_CP023000	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence	849105-849136	7	0.781
NC_016112_5	5.14\|4284579\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284579-4284610	32	MK448487	Streptococcus satellite phage Javan419, complete genome	12427-12458	7	0.781
NC_016112_5	5.14\|4284579\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284579-4284610	32	NC_048182	Edwardsiella virus pEt-SU, complete genome	197627-197658	7	0.781
NC_016112_5	5.20\|4284945\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284945-4284976	32	NZ_CP043622	Rhodobacteraceae bacterium SH-1 plasmid p4, complete sequence	14753-14784	7	0.781
NC_016112_5	5.29\|4285494\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285494-4285525	32	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1060595-1060626	7	0.781
NC_016112_3	3.16\|2436088\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	2436088-2436119	32	NZ_CP047177	Rathayibacter sp. VKM Ac-2759 plasmid unnamed1, complete sequence	99239-99270	8	0.75
NC_016112_5	5.5\|4284027\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284027-4284058	32	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	497442-497473	8	0.75
NC_016112_5	5.6\|4284088\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284088-4284119	32	NZ_CP035502	Sphingosinicella sp. BN140058 plasmid p1, complete sequence	130668-130699	8	0.75
NC_016112_5	5.16\|4284701\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284701-4284732	32	NC_010632	Nostoc punctiforme PCC 73102 plasmid pNPUN02, complete sequence	166470-166501	8	0.75
NC_016112_5	5.23\|4285128\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285128-4285159	32	CP008937	Candidatus Caedibacter acanthamoebae plasmid Plasmid_00001, complete sequence	5969-6000	8	0.75
NC_016112_5	5.23\|4285128\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285128-4285159	32	CP008940	Candidatus Caedibacter acanthamoebae plasmid Plasmid_00004, complete sequence	6106-6137	8	0.75
NC_016112_5	5.33\|4285738\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285738-4285769	32	NC_011143	Phenylobacterium zucineum HLK1 plasmid, complete sequence	3460-3491	8	0.75
NC_016112_5	5.33\|4285738\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285738-4285769	32	NZ_CP015042	Rhodovulum sp. P5 plasmid pRGUI03, complete sequence	25652-25683	8	0.75
NC_016112_3	3.26\|2436751\|33\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	2436751-2436783	33	MH248138	Erwinia phage vB_EamM_Alexandra, complete genome	126479-126511	9	0.727
NC_016112_3	3.28\|2436880\|33\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	2436880-2436912	33	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	1296090-1296122	9	0.727
NC_016112_3	3.32\|2437139\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	2437139-2437170	32	NC_014534	Gloeothece verrucosa PCC 7822 plasmid Cy782202, complete sequence	372534-372565	9	0.719
NC_016112_5	5.4\|4283966\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4283966-4283997	32	NC_017805	Deinococcus gobiensis I-0 plasmid P1, complete sequence	186808-186839	9	0.719
NC_016112_5	5.20\|4284945\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284945-4284976	32	NZ_CP013276	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-1-360K, complete sequence	262626-262657	9	0.719
NC_016112_5	5.20\|4284945\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284945-4284976	32	NZ_CP039722	Bacillus thuringiensis strain BT-59 plasmid p1, complete sequence	40415-40446	9	0.719
NC_016112_5	5.20\|4284945\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284945-4284976	32	NZ_CP023246	Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence	460781-460812	9	0.719
NC_016112_5	5.20\|4284945\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284945-4284976	32	NZ_CP009349	Bacillus thuringiensis HD1002 plasmid 1, complete sequence	338698-338729	9	0.719
NC_016112_5	5.20\|4284945\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284945-4284976	32	NZ_CP045023	Bacillus thuringiensis strain JW-1 plasmid p1, complete sequence	262627-262658	9	0.719
NC_016112_5	5.24\|4285189\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285189-4285220	32	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	123710-123741	9	0.719
NC_016112_5	5.24\|4285189\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285189-4285220	32	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	314605-314636	9	0.719
NC_016112_5	5.24\|4285189\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285189-4285220	32	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	1617991-1618022	9	0.719
NC_016112_5	5.24\|4285189\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285189-4285220	32	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	625104-625135	9	0.719
NC_016112_5	5.24\|4285189\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285189-4285220	32	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	818062-818093	9	0.719
NC_016112_5	5.24\|4285189\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285189-4285220	32	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	1575144-1575175	9	0.719
NC_016112_5	5.34\|4285799\|32\|NC_016112\|CRISPRCasFinder,CRT	4285799-4285830	32	NC_048182	Edwardsiella virus pEt-SU, complete genome	201278-201309	9	0.719
NC_016112_2	2.2\|1516573\|34\|NC_016112\|PILER-CR,CRISPRCasFinder,CRT	1516573-1516606	34	NZ_CP016362	Bacillus cereus strain M13 plasmid pBCM1302, complete sequence	9528-9561	10	0.706
NC_016112_2	2.7\|1516928\|35\|NC_016112\|PILER-CR,CRISPRCasFinder,CRT	1516928-1516962	35	KR053195	Gordonia phage GMA1, complete genome	23902-23936	10	0.714
NC_016112_2	2.8\|1517000\|34\|NC_016112\|PILER-CR,CRISPRCasFinder,CRT	1517000-1517033	34	NC_022876	Bacillus thuringiensis YBT-1518 plasmid pBMB0231, complete sequence	102607-102640	10	0.706
NC_016112_2	2.41\|1519366\|33\|NC_016112\|PILER-CR	1519366-1519398	33	NC_048791	Corynebacterium phage Adelaide, complete genome	19812-19844	10	0.697
NC_016112_2	2.69\|1519362\|33\|NC_016112\|CRISPRCasFinder,CRT	1519362-1519394	33	NC_048791	Corynebacterium phage Adelaide, complete genome	19812-19844	10	0.697
NC_016112_3	3.8\|2435575\|33\|NC_016112\|PILER-CR,CRISPRCasFinder,CRT	2435575-2435607	33	MG945597	UNVERIFIED: Microviridae sp. isolate 4321-1602, complete genome	3254-3286	10	0.697
NC_016112_5	5.8\|4284211\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284211-4284242	32	NZ_CP035502	Sphingosinicella sp. BN140058 plasmid p1, complete sequence	345643-345674	10	0.688
NC_016112_5	5.15\|4284640\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284640-4284671	32	NZ_CP044550	Hydrogenophaga sp. BPS33 plasmid pBPS33-1, complete sequence	43727-43758	10	0.688
NC_016112_5	5.17\|4284762\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284762-4284793	32	MK919481	Gordonia phage Newt, complete genome	62413-62444	10	0.688
NC_016112_5	5.17\|4284762\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4284762-4284793	32	MK878903	Gordonia phage Teal, complete genome	62390-62421	10	0.688
NC_016112_5	5.24\|4285189\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285189-4285220	32	NZ_CP031947	Ruegeria sp. AD91A plasmid unnamed1, complete sequence	395778-395809	10	0.688
NC_016112_5	5.31\|4285616\|32\|NC_016112\|CRISPRCasFinder,CRT,PILER-CR	4285616-4285647	32	NZ_CP021071	Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence	64441-64472	10	0.688
NC_016112_2	2.35\|1518936\|34\|NC_016112\|PILER-CR	1518936-1518969	34	NZ_CP021025	Rhizobium sp. TAL182 plasmid pRetTAL182a, complete sequence	18034-18067	11	0.676
NC_016112_2	2.35\|1518936\|34\|NC_016112\|PILER-CR	1518936-1518969	34	NZ_CP013512	Rhizobium sp. N1314 plasmid pRspN1314a, complete sequence	18035-18068	11	0.676
NC_016112_2	2.63\|1518932\|34\|NC_016112\|CRISPRCasFinder,CRT	1518932-1518965	34	NZ_CP021025	Rhizobium sp. TAL182 plasmid pRetTAL182a, complete sequence	18034-18067	11	0.676
NC_016112_2	2.63\|1518932\|34\|NC_016112\|CRISPRCasFinder,CRT	1518932-1518965	34	NZ_CP013512	Rhizobium sp. N1314 plasmid pRspN1314a, complete sequence	18035-18068	11	0.676
NC_016112_3	3.9\|2435640\|33\|NC_016112\|PILER-CR,CRISPRCasFinder,CRT	2435640-2435672	33	NZ_CP011453	Altererythrobacter atlanticus strain 26DY36 plasmid unnamed, complete sequence	88130-88162	11	0.667

1. spacer 4.1|3711383|26|NC_016112|CRISPRCasFinder matches to MN693855 (Marine virus AFVG_250M616, complete genome) position: , mismatch: 4, identity: 0.846

tttgcagatttttgctcctgcaaaat	CRISPR spacer
tttgcagatttttggacctgcaaacg	Protospacer
**************  ********

2. spacer 4.1|3711383|26|NC_016112|CRISPRCasFinder matches to NZ_CP024167 (Salmonella enterica subsp. enterica serovar Gaminara strain CFSAN070644 plasmid pCFSAN024441_02, complete sequence) position: , mismatch: 4, identity: 0.846

tttgcagatttttgctcctgcaaaat	CRISPR spacer
gtggcagatttttgcttcagcaaaat	Protospacer
 * *************.* *******

3. spacer 5.25|4285250|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029460 (Clostridium novyi strain 150557 plasmid pCN2, complete sequence) position: , mismatch: 5, identity: 0.844

tttttataatgtttgttcatgattcggtttgt	CRISPR spacer
tatacataatgtttgttcataattaggtttgt	Protospacer
* * .***************.*** *******

4. spacer 2.2|1516573|34|NC_016112|PILER-CR,CRISPRCasFinder,CRT matches to MK241539 (Alteromonas phage P24, complete genome) position: , mismatch: 6, identity: 0.824

atgacaactcaaacagcaaatcaagtaaaaccgc--	CRISPR spacer
atgacagctcaaacagcaaagcaa--aaagcggcag	Protospacer
******.************* ***  ***.* **

5. spacer 2.43|1519516|35|NC_016112|PILER-CR matches to NZ_CP050100 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b3, complete sequence) position: , mismatch: 6, identity: 0.829

-aagcgcgttcggcgaggccgccggcagtatcctgg	CRISPR spacer
gaagggcg-acggcgaggccgcccgcaggatcctgc	Protospacer
 *** ***  ************* **** ******

6. spacer 2.71|1519512|35|NC_016112|CRISPRCasFinder,CRT matches to NZ_CP050100 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b3, complete sequence) position: , mismatch: 6, identity: 0.829

-aagcgcgttcggcgaggccgccggcagtatcctgg	CRISPR spacer
gaagggcg-acggcgaggccgcccgcaggatcctgc	Protospacer
 *** ***  ************* **** ******

7. spacer 5.15|4284640|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014803 (Salipiger profundus strain JLT2016 plasmid pTPRO7, complete sequence) position: , mismatch: 6, identity: 0.812

cgtccagaaccgatcgcacgaccg--cagccgga	CRISPR spacer
cgtccagaaccgatcgcaagatcgatgagctg--	Protospacer
****************** **.**   ***.*

8. spacer 5.23|4285128|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to MN693592 (Marine virus AFVG_25M471, complete genome) position: , mismatch: 6, identity: 0.812

aaatcaa--acgcacatgaattcgtcatttacaa	CRISPR spacer
--ttcaattgcgcacaggaaatcgtcatttacaa	Protospacer
   ****  .****** *** *************

9. spacer 5.23|4285128|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to MN693131 (Marine virus AFVG_25M472, complete genome) position: , mismatch: 6, identity: 0.812

aaatcaa--acgcacatgaattcgtcatttacaa	CRISPR spacer
--ttcaattgcgcacaggaaatcgtcatttacaa	Protospacer
   ****  .****** *** *************

10. spacer 3.26|2436751|33|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025432 (Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence) position: , mismatch: 7, identity: 0.788

-tgcccgtgcgccttcgtcgctgcggattgtgtt	CRISPR spacer
gcacccat-cgccttcgtcgctgaggatcgtgtg	Protospacer
 ..***.* ************** ****.****

11. spacer 3.28|2436880|33|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011481 (Hoeflea sp. IMCC20628 plasmid, complete sequence) position: , mismatch: 7, identity: 0.788

tcgaaaggcctggaattcgtcaaagactcggtc---	CRISPR spacer
gagaaccgcctggaattcgtcaaaga---ggtcaag	Protospacer
  ***  *******************   ****

12. spacer 5.6|4284088|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023000 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence) position: , mismatch: 7, identity: 0.781

ctgcagccgctttcgcgctctcgtcatcctgg	CRISPR spacer
cctcagccgcttgcgggctctcgtcatcgagt	Protospacer
*. ********* ** ************  *

13. spacer 5.14|4284579|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to MK448487 (Streptococcus satellite phage Javan419, complete genome) position: , mismatch: 7, identity: 0.781

tgctaaaaacagaagctgaaaaccgaaaagaa	CRISPR spacer
ctaaagaaaaagaagctgaaaaacgaaaagaa	Protospacer
.   *.*** ************ *********

14. spacer 5.14|4284579|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NC_048182 (Edwardsiella virus pEt-SU, complete genome) position: , mismatch: 7, identity: 0.781

-tgctaaaaacagaagctgaaaaccgaaaagaa	CRISPR spacer
atgcctgaag-agaagctgaaaactgaaaagga	Protospacer
 ***. .**. *************.******.*

15. spacer 5.20|4284945|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043622 (Rhodobacteraceae bacterium SH-1 plasmid p4, complete sequence) position: , mismatch: 7, identity: 0.781

ttctgcaaatactccaaccgctccaacaaccg	CRISPR spacer
tcctgcaaaaactccaaccggtccagaagtcg	Protospacer
*.******* ********** ****. *..**

16. spacer 5.29|4285494|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

cgtgtactttcagccgtatctgatgcaaatgg	CRISPR spacer
gatgatttttcagacgtatctgatgcaaatcg	Protospacer
 .**  .****** **************** *

17. spacer 3.16|2436088|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047177 (Rathayibacter sp. VKM Ac-2759 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ttgacgcgcttcgtcacggggtcagcgcattt	CRISPR spacer
acggcccgcctcgtcacggcgtcagcgcacgt	Protospacer
 .*.* ***.********* *********. *

18. spacer 5.5|4284027|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

ttgttggcttcttcggacgcgcgctgtagcac	CRISPR spacer
gcaatcccgtcttcggacgcgcgctggagcac	Protospacer
 .. *  * ***************** *****

19. spacer 5.6|4284088|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035502 (Sphingosinicella sp. BN140058 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

ctgcagccgctttcgcgctctcgtcatcctgg	CRISPR spacer
tcgcgaccgcgttcgcgcgctcgtcatccgcg	Protospacer
..**..**** ******* **********  *

20. spacer 5.16|4284701|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NC_010632 (Nostoc punctiforme PCC 73102 plasmid pNPUN02, complete sequence) position: , mismatch: 8, identity: 0.75

--ttggctacgggcataacctagactcaaagcca	CRISPR spacer
tgctgatt--gggcataacctagcttcaaagcct	Protospacer
  .**..*  ************* .********

21. spacer 5.23|4285128|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to CP008937 (Candidatus Caedibacter acanthamoebae plasmid Plasmid_00001, complete sequence) position: , mismatch: 8, identity: 0.75

aaatca-aacgcacatgaattcgtcatttacaa	CRISPR spacer
-cttcataagggacatgaattcgtcatttaatt	Protospacer
   *** ** * ******************

22. spacer 5.23|4285128|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to CP008940 (Candidatus Caedibacter acanthamoebae plasmid Plasmid_00004, complete sequence) position: , mismatch: 8, identity: 0.75

aaatca-aacgcacatgaattcgtcatttacaa	CRISPR spacer
-cttcataagggacatgaattcgtcatttaatt	Protospacer
   *** ** * ******************

23. spacer 5.33|4285738|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NC_011143 (Phenylobacterium zucineum HLK1 plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

-----ccccaacagcatgccaagcccttcttgagaag	CRISPR spacer
agatgccct-----catgccaagccctccttgcgaag	Protospacer
     ***.     *************.**** ****

24. spacer 5.33|4285738|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015042 (Rhodovulum sp. P5 plasmid pRGUI03, complete sequence) position: , mismatch: 8, identity: 0.75

-ccccaacagcatgccaagcccttcttgagaag	CRISPR spacer
aatccgat-gcatgcccagcccttcttgggaac	Protospacer
  .**.*. ******* ***********.***

25. spacer 3.26|2436751|33|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to MH248138 (Erwinia phage vB_EamM_Alexandra, complete genome) position: , mismatch: 9, identity: 0.727

tgcccgtgcgccttcgtcgctgcggattgtgtt	CRISPR spacer
atagttcgcgctttcttcgctgcggattgtgtt	Protospacer
    . .****.*** *****************

26. spacer 3.28|2436880|33|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 9, identity: 0.727

tcgaaaggcctggaattcgtcaaagactcggtc	CRISPR spacer
ctcgattgcctggacttcgtcaaagacccggac	Protospacer
.. .*  ******* ************.*** *

27. spacer 3.32|2437139|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NC_014534 (Gloeothece verrucosa PCC 7822 plasmid Cy782202, complete sequence) position: , mismatch: 9, identity: 0.719

gtcagttcgttttgcgtcattcggccctccgg	CRISPR spacer
tcgttttcgttttgcgtcattggtccctcaag	Protospacer
 .   **************** * ***** .*

28. spacer 5.4|4283966|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NC_017805 (Deinococcus gobiensis I-0 plasmid P1, complete sequence) position: , mismatch: 9, identity: 0.719

atagctagtcccggctggatttcggtcgccga	CRISPR spacer
gccgctgctcccggctggatttcggtaggcct	Protospacer
.. ***. ****************** * *

29. spacer 5.20|4284945|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013276 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-1-360K, complete sequence) position: , mismatch: 9, identity: 0.719

ttctgcaaatactccaaccgctccaacaaccg	CRISPR spacer
tgctgcaaatactccaactgatccagagaata	Protospacer
* ****************.* ****. .* ..

30. spacer 5.20|4284945|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039722 (Bacillus thuringiensis strain BT-59 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttctgcaaatactccaaccgctccaacaaccg	CRISPR spacer
tgctgcaaatactccaactgatccagagaata	Protospacer
* ****************.* ****. .* ..

31. spacer 5.20|4284945|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023246 (Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ttctgcaaatactccaaccgctccaacaaccg	CRISPR spacer
tgctgcaaatactccaactgatccagagaata	Protospacer
* ****************.* ****. .* ..

32. spacer 5.20|4284945|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009349 (Bacillus thuringiensis HD1002 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

ttctgcaaatactccaaccgctccaacaaccg	CRISPR spacer
tgctgcaaatactccaactgatccagagaata	Protospacer
* ****************.* ****. .* ..

33. spacer 5.20|4284945|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045023 (Bacillus thuringiensis strain JW-1 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttctgcaaatactccaaccgctccaacaaccg	CRISPR spacer
tgctgcaaatactccaactgatccagagaata	Protospacer
* ****************.* ****. .* ..

34. spacer 5.24|4285189|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 9, identity: 0.719

ggagatgaaccgcaagagcaaggcgctggacc	CRISPR spacer
ccgcaagaaccgcacgagcaaggtgctggtca	Protospacer
  . * ******** ********.***** *

35. spacer 5.24|4285189|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 9, identity: 0.719

ggagatgaaccgcaagagcaaggcgctggacc	CRISPR spacer
ccgcaagaaccgcacgagcaaggtgctggtca	Protospacer
  . * ******** ********.***** *

36. spacer 5.24|4285189|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 9, identity: 0.719

ggagatgaaccgcaagagcaaggcgctggacc	CRISPR spacer
ccgcaagaaccgcacgagcaaggtgctggtca	Protospacer
  . * ******** ********.***** *

37. spacer 5.24|4285189|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

ggagatgaaccgcaagagcaaggcgctggacc	CRISPR spacer
ccgcaagaaccgcacgagcaaggtgctggtca	Protospacer
  . * ******** ********.***** *

38. spacer 5.24|4285189|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

ggagatgaaccgcaagagcaaggcgctggacc	CRISPR spacer
ccgcaagaaccgcacgagcaaggtgctggtca	Protospacer
  . * ******** ********.***** *

39. spacer 5.24|4285189|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

ggagatgaaccgcaagagcaaggcgctggacc	CRISPR spacer
ccgcaagaaccgcacgagcaaggtgctggtca	Protospacer
  . * ******** ********.***** *

40. spacer 5.34|4285799|32|NC_016112|CRISPRCasFinder,CRT matches to NC_048182 (Edwardsiella virus pEt-SU, complete genome) position: , mismatch: 9, identity: 0.719

ttgacacccgtaccggcagcaaaggccgtatc	CRISPR spacer
cgagaacccgtaccggcagcaaagccagtgtt	Protospacer
. .. ******************* * **.*.

41. spacer 2.2|1516573|34|NC_016112|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016362 (Bacillus cereus strain M13 plasmid pBCM1302, complete sequence) position: , mismatch: 10, identity: 0.706

atgacaactcaaacagcaaatcaagtaaaaccgc	CRISPR spacer
atgacaacccaaacaacaaatcaaaatcctacac	Protospacer
********.******.********.      *.*

42. spacer 2.7|1516928|35|NC_016112|PILER-CR,CRISPRCasFinder,CRT matches to KR053195 (Gordonia phage GMA1, complete genome) position: , mismatch: 10, identity: 0.714

atgccatcgacgatgccggggaggttacgcatttt	CRISPR spacer
gtgccttcgatgatgccggggaggttgtcaacgtg	Protospacer
.**** ****.***************..  *. *

43. spacer 2.8|1517000|34|NC_016112|PILER-CR,CRISPRCasFinder,CRT matches to NC_022876 (Bacillus thuringiensis YBT-1518 plasmid pBMB0231, complete sequence) position: , mismatch: 10, identity: 0.706

gtgccaattttgacaattttgtgcatcaagcggt	CRISPR spacer
ttctaaatttttacaattttatgcatcaaaaaga	Protospacer
 * . ****** ********.********. .*

44. spacer 2.41|1519366|33|NC_016112|PILER-CR matches to NC_048791 (Corynebacterium phage Adelaide, complete genome) position: , mismatch: 10, identity: 0.697

cttccggtttttgcacgatatgcgctaaccaat	CRISPR spacer
gttccggtttttgcgcgatttgcgcagggtcaa	Protospacer
 *************.**** ***** .. . *

45. spacer 2.69|1519362|33|NC_016112|CRISPRCasFinder,CRT matches to NC_048791 (Corynebacterium phage Adelaide, complete genome) position: , mismatch: 10, identity: 0.697

cttccggtttttgcacgatatgcgctaaccaat	CRISPR spacer
gttccggtttttgcgcgatttgcgcagggtcaa	Protospacer
 *************.**** ***** .. . *

46. spacer 3.8|2435575|33|NC_016112|PILER-CR,CRISPRCasFinder,CRT matches to MG945597 (UNVERIFIED: Microviridae sp. isolate 4321-1602, complete genome) position: , mismatch: 10, identity: 0.697

gtaatataacttctactgctgtcaattacgcta	CRISPR spacer
tggttgccacttctactgctggtaattacgctg	Protospacer
  . *.. ************* .*********.

47. spacer 5.8|4284211|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035502 (Sphingosinicella sp. BN140058 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

acgcgaggtgctcgaatgaaaggcgttgggtc	CRISPR spacer
cccttgaacgctcgaatgaacggcgtggggtc	Protospacer
 * . ....*********** ***** *****

48. spacer 5.15|4284640|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044550 (Hydrogenophaga sp. BPS33 plasmid pBPS33-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgtccagaaccgatcgcacgaccgcagccgga	CRISPR spacer
acgatagaaccgatcgaactaccgcagctgat	Protospacer
    .*********** ** ********.*.

49. spacer 5.17|4284762|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to MK919481 (Gordonia phage Newt, complete genome) position: , mismatch: 10, identity: 0.688

ctcagcggtcgaatcccaagactggtatcaag	CRISPR spacer
tcgagcggaagaatcccaagactggtcggtac	Protospacer
.. *****  ****************    *

50. spacer 5.17|4284762|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to MK878903 (Gordonia phage Teal, complete genome) position: , mismatch: 10, identity: 0.688

ctcagcggtcgaatcccaagactggtatcaag	CRISPR spacer
tcgagcggaagaatcccaagactggtcggtac	Protospacer
.. *****  ****************    *

51. spacer 5.24|4285189|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031947 (Ruegeria sp. AD91A plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ggagatgaaccgcaagagcaaggcgctggacc	CRISPR spacer
caagatgatccgcaagatcaaggcgtccaaag	Protospacer
 .****** ******** *******.. .*

52. spacer 5.31|4285616|32|NC_016112|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021071 (Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence) position: , mismatch: 10, identity: 0.688

taggaaagcggcacccatgcccacaatagcag	CRISPR spacer
aggcggcccggcacccttgccgacaatagcaa	Protospacer
 .* ..  ******** **** *********.

53. spacer 2.35|1518936|34|NC_016112|PILER-CR matches to NZ_CP021025 (Rhizobium sp. TAL182 plasmid pRetTAL182a, complete sequence) position: , mismatch: 11, identity: 0.676

gtgtcggacccgttcaatgccgacgtattgccgc	CRISPR spacer
acccggccttcgttcaatgtcgccgtattgccgc	Protospacer
.. . *  ..*********.** ***********

54. spacer 2.35|1518936|34|NC_016112|PILER-CR matches to NZ_CP013512 (Rhizobium sp. N1314 plasmid pRspN1314a, complete sequence) position: , mismatch: 11, identity: 0.676

gtgtcggacccgttcaatgccgacgtattgccgc	CRISPR spacer
acccggccttcgttcaatgtcgccgtattgccgc	Protospacer
.. . *  ..*********.** ***********

55. spacer 2.63|1518932|34|NC_016112|CRISPRCasFinder,CRT matches to NZ_CP021025 (Rhizobium sp. TAL182 plasmid pRetTAL182a, complete sequence) position: , mismatch: 11, identity: 0.676

gtgtcggacccgttcaatgccgacgtattgccgc	CRISPR spacer
acccggccttcgttcaatgtcgccgtattgccgc	Protospacer
.. . *  ..*********.** ***********

56. spacer 2.63|1518932|34|NC_016112|CRISPRCasFinder,CRT matches to NZ_CP013512 (Rhizobium sp. N1314 plasmid pRspN1314a, complete sequence) position: , mismatch: 11, identity: 0.676

gtgtcggacccgttcaatgccgacgtattgccgc	CRISPR spacer
acccggccttcgttcaatgtcgccgtattgccgc	Protospacer
.. . *  ..*********.** ***********

57. spacer 3.9|2435640|33|NC_016112|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011453 (Altererythrobacter atlanticus strain 26DY36 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.667

ggctacgactggcacatgatcgtcgacaactgg	CRISPR spacer
aaggccgactggcagctgatcgtcgacaatatc	Protospacer
..   *********  *************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

97232 : 105340

Moraxella_phage(16.67%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046060912.1\|97232_98243_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.1e-100	56.6
WP_014146611.1\|98348_98582_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_014146612.1\|98604_99054_+	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	2.7e-27	50.4
WP_014146613.1\|99095_100820_+	DNA primase	A0A1S5RFN0	Helicobacter_phage	1.6e-43	33.1
WP_014146614.1\|100907_102719_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	2.8e-35	33.7
WP_014146615.1\|102867_104028_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.0e-127	60.9
WP_014146616.1\|104047_105340_+	adenosylhomocysteinase	S4VPF6	Pandoravirus	5.5e-49	32.1

DBSCAN-SWA_2

160388 : 215682

Acinetobacter_phage(27.27%)

tRNA,integrase,transposase

attL 206238:206286|attR 211627:211675

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014146661.1\|160388_162149_+\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_048481356.1\|162237_162744_+	SPOR domain-containing protein	NA	NA	NA	NA
WP_014146663.1\|164922_165726_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	1.3e-69	53.1
WP_014146664.1\|165722_166757_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	6.2e-88	49.7
WP_014146665.1\|166845_167436_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.3e-74	65.8
WP_046061296.1\|167432_168920_-	anthranilate synthase component I	NA	NA	NA	NA
WP_014146667.1\|169367_170240_+	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_014146668.1\|170248_171703_-	two-component sensor histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	5.4e-05	22.7
WP_014146669.1\|171702_172362_-	response regulator	NA	NA	NA	NA
WP_014146670.1\|172734_173883_+	radical SAM family heme chaperone HemW	NA	NA	NA	NA
WP_014146671.1\|174234_174876_+	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_014146672.1\|175020_176961_+	dynamin family protein	NA	NA	NA	NA
WP_014146673.1\|177244_177934_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_014146674.1\|178523_179501_-	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_014146675.1\|179515_180586_-	3-deoxy-7-phosphoheptulonate synthase AroG	A0A0U2D9U5	Escherichia_phage	8.2e-83	46.8
WP_014146676.1\|180835_182650_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.3e-35	26.6
WP_014146677.1\|182671_184612_-	DUF389 domain-containing protein	NA	NA	NA	NA
WP_014146678.1\|184809_185121_+	DUF3301 domain-containing protein	NA	NA	NA	NA
WP_014146679.1\|185205_185520_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_014146680.1\|185516_185717_+	DUF1289 domain-containing protein	NA	NA	NA	NA
WP_014146681.1\|186020_186395_-	hypothetical protein	NA	NA	NA	NA
WP_014146682.1\|186808_187843_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_014146683.1\|188560_188791_+	hypothetical protein	NA	NA	NA	NA
WP_017841309.1\|189052_189223_+	heavy metal translocating P-type ATPase metal-binding domain-containing protein	NA	NA	NA	NA
WP_138767261.1\|189312_189558_+	hypothetical protein	NA	NA	NA	NA
WP_014146686.1\|189808_190417_+	hypothetical protein	NA	NA	NA	NA
WP_014146687.1\|190509_192960_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.8e-101	34.6
WP_014146688.1\|192968_193796_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_014146689.1\|194348_195185_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_014146690.1\|195207_196098_+	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_014146691.1\|196252_196909_+	thiopurine S-methyltransferase	NA	NA	NA	NA
WP_162472897.1\|199569_199743_+	hypothetical protein	NA	NA	NA	NA
WP_014146694.1\|199739_200156_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_014146695.1\|200327_200510_-	PLDc N-terminal domain-containing protein	NA	NA	NA	NA
WP_014146696.1\|200829_201150_-	hypothetical protein	NA	NA	NA	NA
WP_014146701.1\|204417_205659_-	hypothetical protein	NA	NA	NA	NA
WP_014146702.1\|205742_205943_-	hypothetical protein	NA	NA	NA	NA
206238:206286	attL	NA	NA	NA	NA
WP_014146703.1\|206458_206905_+	DUF4102 domain-containing protein	NA	NA	NA	NA
WP_014146704.1\|206871_207672_+\|integrase	tyrosine-type recombinase/integrase	A0A0R6PGY7	Moraxella_phage	1.6e-14	27.0
WP_014146705.1\|207649_207877_+	type II toxin-antitoxin system VapB family antitoxin	NA	NA	NA	NA
WP_014146706.1\|207860_208127_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5S8E8	Streptococcus_phage	9.5e-17	41.9
WP_014146707.1\|208227_209061_+	hypothetical protein	NA	NA	NA	NA
WP_014146708.1\|209259_209580_+	hypothetical protein	NA	NA	NA	NA
WP_046060919.1\|209637_210936_+\|transposase	transposase	NA	NA	NA	NA
WP_014146710.1\|210986_211421_+	hypothetical protein	NA	NA	NA	NA
WP_162472999.1\|212009_212753_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
211627:211675	attR	NA	NA	NA	NA
WP_014146712.1\|212877_214437_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-24	30.3
WP_014146713.1\|214423_215170_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.5e-46	42.7
WP_162472898.1\|215265_215682_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

2171762 : 2247735

Ralstonia_phage(20.0%)

tRNA,protease,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014148372.1\|2171762_2172638_-\|protease	protease HtpX	NA	NA	NA	NA
WP_014148373.1\|2172755_2173862_+	sorbosone dehydrogenase family protein	NA	NA	NA	NA
WP_014148374.1\|2174042_2174645_+	NUDIX domain-containing protein	A0A1S6L1P8	Vibrio_phage	4.1e-23	33.3
WP_014148375.1\|2174655_2175030_-	membrane protein	NA	NA	NA	NA
WP_014148376.1\|2175699_2176971_+	Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB	A0A218MKK1	uncultured_virus	1.2e-11	24.3
WP_014148377.1\|2176974_2177982_+	NAD-dependent epimerase	M1NML0	Moumouvirus	5.6e-33	28.4
WP_014148378.1\|2178057_2178447_+	four helix bundle protein	NA	NA	NA	NA
WP_014148379.1\|2178604_2179747_+	TIGR03088 family PEP-CTERM/XrtA system glycosyltransferase	NA	NA	NA	NA
WP_014148380.1\|2180002_2181886_+	amidotransferase 1, exosortase A system-associated	A0A2K9L714	Tupanvirus	4.2e-26	25.5
WP_014148381.1\|2181980_2182562_+	hypothetical protein	NA	NA	NA	NA
WP_014148382.1\|2182608_2182902_+	HPr-rel-A system PqqD family peptide chaperone	NA	NA	NA	NA
WP_046061488.1\|2182930_2183797_+	HprK-related kinase A	NA	NA	NA	NA
WP_014148384.1\|2183801_2184932_+	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_014148385.1\|2184994_2185264_-	PilZ domain-containing protein	NA	NA	NA	NA
WP_014148386.1\|2185349_2186657_-	YihY family inner membrane protein	NA	NA	NA	NA
WP_014148387.1\|2187115_2189698_+	response regulator	A0A1V0SGX0	Hokovirus	3.5e-47	34.6
WP_014148388.1\|2189690_2190485_+	cytochrome c	NA	NA	NA	NA
WP_014148389.1\|2191005_2194200_-	EAL domain-containing protein	NA	NA	NA	NA
WP_014148390.1\|2194346_2196056_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_017839390.1\|2196328_2196517_+	hypothetical protein	NA	NA	NA	NA
WP_014148391.1\|2196768_2197944_+	3-hexulose-6-phosphate synthase	NA	NA	NA	NA
WP_046061080.1\|2198843_2200223_+	MFS transporter	NA	NA	NA	NA
WP_014148393.1\|2200477_2200960_+	single-stranded DNA-binding protein	F8TUL2	EBPR_podovirus	4.5e-41	55.2
WP_014148394.1\|2201110_2201869_+	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_014148395.1\|2201876_2202707_+	flagellar motor protein MotB	NA	NA	NA	NA
WP_014148396.1\|2202766_2203348_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_014148397.1\|2203423_2204413_+	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor	NA	NA	NA	NA
WP_014148398.1\|2204417_2205329_+	type III pantothenate kinase	NA	NA	NA	NA
WP_014148399.1\|2205332_2206355_+	hypothetical protein	NA	NA	NA	NA
WP_014148400.1\|2206638_2207487_+	serine hydrolase	NA	NA	NA	NA
WP_046061492.1\|2208265_2209546_+	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_014148402.1\|2209817_2210531_-	DUF2490 domain-containing protein	NA	NA	NA	NA
WP_014148403.1\|2210992_2211712_-	SIMPL domain-containing protein	NA	NA	NA	NA
WP_014148404.1\|2212254_2213724_+	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_014148405.1\|2214106_2215444_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_048481331.1\|2215422_2216811_+	type VI secretion system protein TssL	NA	NA	NA	NA
WP_014148407.1\|2216807_2220371_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_014148408.1\|2220370_2221969_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_046061081.1\|2222005_2223049_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_014148410.1\|2223096_2223627_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_014148411.1\|2223630_2225130_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_014148412.1\|2225250_2225742_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_026130017.1\|2226111_2226915_+	virulence protein SciE type	NA	NA	NA	NA
WP_014148414.1\|2226918_2227419_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_014148415.1\|2227422_2229303_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_046061495.1\|2229266_2230283_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_014148417.1\|2230617_2233335_+	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	7.4e-80	29.4
WP_014148418.1\|2233404_2233935_+	hypothetical protein	NA	NA	NA	NA
WP_014148419.1\|2234048_2234663_+	hypothetical protein	NA	NA	NA	NA
WP_014148420.1\|2234947_2236891_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	5.1e-51	31.1
WP_014148421.1\|2236901_2237489_+	hypothetical protein	NA	NA	NA	NA
WP_014148422.1\|2237821_2238115_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_014148423.1\|2238897_2241030_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.1e-51	30.8
WP_014148424.1\|2241262_2241748_+	hypothetical protein	NA	NA	NA	NA
WP_014148425.1\|2241749_2242865_+	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_014148426.1\|2242904_2243117_+	hypothetical protein	NA	NA	NA	NA
WP_014148427.1\|2243158_2244196_+	3-oxoacyl-ACP synthase	NA	NA	NA	NA
WP_014148428.1\|2244195_2245326_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_014148429.1\|2245344_2246184_+	hypothetical protein	NA	NA	NA	NA
WP_162473010.1\|2246312_2247735_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.5e-11	25.7

DBSCAN-SWA_4

2399386 : 2474576

uncultured_phage(22.22%)

plate,integrase,tail,transposase

attL 2405486:2405515|attR 2424600:2424629

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046061100.1\|2399386_2400685_+\|transposase	transposase	NA	NA	NA	NA
WP_014148594.1\|2400713_2401712_-	serine/threonine protein kinase	A7IWR3	Paramecium_bursaria_Chlorella_virus	2.8e-08	26.6
WP_014148595.1\|2401716_2402265_-	FHA domain-containing protein	NA	NA	NA	NA
WP_014148596.1\|2402310_2403066_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_014148598.1\|2403964_2404387_+	putative toxin-antitoxin system toxin component, PIN family	NA	NA	NA	NA
WP_014148599.1\|2404383_2404593_+	hypothetical protein	NA	NA	NA	NA
WP_046061520.1\|2405138_2405390_+	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
2405486:2405515	attL	NA	NA	NA	NA
WP_046061101.1\|2405566_2405824_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_162472943.1\|2406198_2407083_-	DUF3262 family protein	A0A1B4XX13	Tenacibaculum_phage	5.3e-19	37.6
WP_014148603.1\|2407086_2407539_-	hypothetical protein	NA	NA	NA	NA
WP_014148604.1\|2407549_2408092_-	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_162472944.1\|2408132_2408903_-	TIGR03759 family integrating conjugative element protein	NA	NA	NA	NA
WP_014148606.1\|2408933_2409485_-	hypothetical protein	NA	NA	NA	NA
WP_014148607.1\|2409504_2410218_-	hypothetical protein	NA	NA	NA	NA
WP_162473003.1\|2410481_2411904_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.5e-11	25.7
WP_014148609.1\|2412474_2413758_+	DUF429 domain-containing protein	NA	NA	NA	NA
WP_046061102.1\|2414040_2414601_-	recombinase family protein	M9Q1K0	Clostridium_phage	3.2e-38	51.4
WP_014148612.1\|2416802_2417336_-	hypothetical protein	NA	NA	NA	NA
WP_014148613.1\|2417429_2418518_-\|integrase	site-specific integrase	D6PIF1	uncultured_phage	3.3e-15	28.3
WP_014148614.1\|2418789_2419881_-	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_014148615.1\|2420048_2420474_-	hypothetical protein	NA	NA	NA	NA
WP_014148616.1\|2420722_2421712_+	folate-binding protein YgfZ	NA	NA	NA	NA
WP_014148617.1\|2422000_2422843_+	HDOD domain-containing protein	A0A1C3NFB0	Phage_NCTB	4.1e-21	30.1
WP_014148618.1\|2422938_2423910_+	COX15/CtaA family protein	NA	NA	NA	NA
WP_014148619.1\|2424038_2424491_-	nucleoside deaminase	NA	NA	NA	NA
WP_014148620.1\|2425227_2425842_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
2424600:2424629	attR	NA	NA	NA	NA
WP_014148621.1\|2425946_2427161_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_014148622.1\|2427167_2430353_+	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_014148623.1\|2430349_2431819_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_014148624.1\|2432062_2432671_-	hypothetical protein	NA	NA	NA	NA
WP_162472945.1\|2432923_2433094_-	hypothetical protein	NA	NA	NA	NA
WP_046061527.1\|2433086_2434094_-	virulence protein RhuM/Fic/DOC family protein	Q9JMN3	Wolbachia_phage	4.9e-21	37.3
WP_014148627.1\|2434104_2434473_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_014148628.1\|2434475_2434670_-	type II toxin-antitoxin system VapB family antitoxin	NA	NA	NA	NA
WP_026130023.1\|2437451_2437742_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_014148631.1\|2437756_2438791_-	type I-C CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_014148632.1\|2438793_2439420_-	CRISPR-associated protein Cas4	NA	NA	NA	NA
WP_014148633.1\|2439480_2440344_-	type I-C CRISPR-associated protein Cas7/Csd2	NA	NA	NA	NA
WP_014148634.1\|2440340_2442371_-	type I-C CRISPR-associated protein Cas8c/Csd1	NA	NA	NA	NA
WP_046061106.1\|2442367_2443072_-	type I-C CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_046061528.1\|2443081_2445538_-	CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
WP_014148637.1\|2445981_2447232_-	group II intron reverse transcriptase/maturase	NA	NA	NA	NA
WP_014148638.1\|2448015_2448285_-	hypothetical protein	NA	NA	NA	NA
WP_014148639.1\|2449108_2450434_-	ATP-binding protein	K9MCS8	Sulfolobus_virus	1.3e-10	33.6
WP_014146701.1\|2451343_2452585_+	hypothetical protein	NA	NA	NA	NA
WP_014148641.1\|2453513_2457017_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_014148642.1\|2457013_2458438_-	hypothetical protein	NA	NA	NA	NA
WP_046061531.1\|2458434_2462220_-	hypothetical protein	NA	NA	NA	NA
WP_014148644.1\|2462236_2465908_-	hypothetical protein	NA	NA	NA	NA
WP_084685595.1\|2465904_2468940_-\|plate	baseplate J/gp47 family protein	NA	NA	NA	NA
WP_014148646.1\|2470305_2470743_-	GPW/gp25 family protein	NA	NA	NA	NA
WP_014148647.1\|2470744_2471014_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_014148648.1\|2471026_2472793_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_014148649.1\|2472789_2473497_-	hypothetical protein	NA	NA	NA	NA
WP_014148650.1\|2473496_2473685_-	hypothetical protein	NA	NA	NA	NA
WP_014148651.1\|2473692_2474133_-\|tail	phage tail protein	NA	NA	NA	NA
WP_014148652.1\|2474138_2474576_-\|tail	phage tail protein	A0A059XEM3	uncultured_phage	1.1e-59	88.0

DBSCAN-SWA_5

3069322 : 3110483

Shigella_phage(14.29%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162473003.1\|3069322_3070745_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.5e-11	25.7
WP_014149117.1\|3071037_3071340_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_014149118.1\|3071341_3072295_-	DnaJ domain-containing protein	K7YGN1	Megavirus	2.1e-13	53.8
WP_014149119.1\|3072804_3073053_-	succinate dehydrogenase assembly factor 2	NA	NA	NA	NA
WP_014149120.1\|3073052_3073838_-	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_014149121.1\|3073837_3075622_-	succinate dehydrogenase flavoprotein subunit	M1HTN0	Paramecium_bursaria_Chlorella_virus	4.9e-16	25.2
WP_014149122.1\|3075624_3076005_-	succinate dehydrogenase, hydrophobic membrane anchor protein	NA	NA	NA	NA
WP_014149123.1\|3076014_3076395_-	succinate dehydrogenase, cytochrome b556 subunit	NA	NA	NA	NA
WP_014149124.1\|3076455_3076626_-	DUF1674 domain-containing protein	NA	NA	NA	NA
WP_014149125.1\|3077116_3078001_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	4.9e-25	40.8
WP_014149126.1\|3078209_3078743_-	hypothetical protein	NA	NA	NA	NA
WP_014149127.1\|3078853_3080653_-	asparagine synthase	A0A1V0SHV8	Klosneuvirus	6.5e-08	30.8
WP_014149128.1\|3080838_3082044_-	glycosyltransferase, exosortase A system-associated	NA	NA	NA	NA
WP_014149131.1\|3084048_3084996_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	1.1e-06	30.2
WP_014149132.1\|3085480_3086386_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_014149133.1\|3086949_3087618_+	hypothetical protein	NA	NA	NA	NA
WP_014149134.1\|3087667_3088258_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_014149135.1\|3088667_3089210_+	hypothetical protein	NA	NA	NA	NA
WP_014149136.1\|3089771_3090692_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_014149137.1\|3090929_3091109_+	hypothetical protein	NA	NA	NA	NA
WP_162472959.1\|3091688_3091991_+	hypothetical protein	NA	NA	NA	NA
WP_014149138.1\|3092232_3092535_+	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_014149140.1\|3093760_3094672_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_014149141.1\|3094867_3095047_-\|transposase	transposase	NA	NA	NA	NA
WP_162472960.1\|3095059_3095236_-	hypothetical protein	NA	NA	NA	NA
WP_014149143.1\|3095655_3096858_+	terpene cyclase/mutase family protein	NA	NA	NA	NA
WP_014149144.1\|3096862_3097675_+	formyl transferase	NA	NA	NA	NA
WP_162472961.1\|3097918_3098257_+	hypothetical protein	NA	NA	NA	NA
WP_014149146.1\|3098776_3100120_-	phenylacetate--CoA ligase family protein	NA	NA	NA	NA
WP_046061583.1\|3101975_3103556_+	acyl-CoA ligase (AMP-forming), exosortase A system-associated	A0A2K9KZV5	Tupanvirus	1.7e-36	25.4
WP_014149148.1\|3103715_3104951_+	pyridoxal-dependent decarboxylase, exosortase A system-associated	NA	NA	NA	NA
WP_014149149.1\|3105021_3106575_+	lipopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_046061156.1\|3106543_3107782_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_162472962.1\|3107838_3108606_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_014149152.1\|3108615_3109383_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014149153.1\|3109470_3109755_+\|transposase	transposase	NA	NA	NA	NA
WP_014149154.1\|3109946_3110483_+\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

3477434 : 3560027

Planktothrix_phage(13.33%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_084685487.1\|3477434_3478601_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_014147681.1\|3478747_3480250_+\|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_014149432.1\|3480574_3481309_+	DUF1538 domain-containing protein	NA	NA	NA	NA
WP_014149433.1\|3481305_3482097_+	DUF1538 domain-containing protein	NA	NA	NA	NA
WP_014149434.1\|3482109_3482460_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_014149435.1\|3482456_3482864_+	CBS domain-containing protein	NA	NA	NA	NA
WP_014149436.1\|3483013_3483217_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	1.2e-16	61.9
WP_014149437.1\|3484576_3486496_-	hypothetical protein	NA	NA	NA	NA
WP_014149438.1\|3486859_3489079_-	TonB-dependent receptor	NA	NA	NA	NA
WP_014149439.1\|3489082_3491641_-	fused MFS/spermidine synthase	NA	NA	NA	NA
WP_014149440.1\|3492243_3493557_-	hypothetical protein	NA	NA	NA	NA
WP_014149441.1\|3494147_3494357_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.2e-14	59.1
WP_014149442.1\|3494726_3495266_+	DUF2796 domain-containing protein	NA	NA	NA	NA
WP_014149443.1\|3495274_3495856_-	DUF3299 domain-containing protein	NA	NA	NA	NA
WP_014149444.1\|3495921_3496611_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.7e-21	31.2
WP_014149445.1\|3496607_3497864_+	ABC transporter permease	NA	NA	NA	NA
WP_162531689.1\|3498124_3498475_-	hypothetical protein	NA	NA	NA	NA
WP_014149446.1\|3498440_3499706_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_014149447.1\|3499705_3500419_-	energy transducer TonB	NA	NA	NA	NA
WP_014149448.1\|3500415_3500823_-	biopolymer transporter ExbD	NA	NA	NA	NA
WP_014149449.1\|3500836_3501337_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_014149450.1\|3501342_3502686_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_162473018.1\|3502682_3503408_-	DUF3450 family protein	NA	NA	NA	NA
WP_014149452.1\|3503975_3505241_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_014149453.1\|3506458_3507766_-	citrate synthase	NA	NA	NA	NA
WP_014149454.1\|3507969_3510540_-	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_014149455.1\|3511105_3512116_-	isocitrate dehydrogenase	NA	NA	NA	NA
WP_014149456.1\|3512281_3512872_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_014149457.1\|3512880_3513645_-	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_014149458.1\|3513764_3514748_-	hydrolase	NA	NA	NA	NA
WP_014149459.1\|3515195_3515600_+	hypothetical protein	NA	NA	NA	NA
WP_014149460.1\|3515850_3517587_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.3e-58	36.2
WP_014149461.1\|3517815_3518535_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.6e-42	40.8
WP_014149462.1\|3518534_3519218_-	carboxylesterase	NA	NA	NA	NA
WP_014147191.1\|3519407_3520637_+\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.2e-13	24.0
WP_014149463.1\|3520670_3524024_-	EAL domain-containing protein	G3MA91	Bacillus_virus	1.3e-22	40.2
WP_014149464.1\|3524020_3524464_-	ribonuclease HI	J9Q745	Salmonella_phage	3.5e-40	54.4
WP_014149465.1\|3524456_3525173_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_014149466.1\|3525262_3526879_+	LysM peptidoglycan-binding domain-containing protein	A0A2H4J9N7	uncultured_Caudovirales_phage	2.1e-13	41.3
WP_014149467.1\|3526933_3528547_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.4e-17	30.4
WP_014149468.1\|3528543_3529875_-	ABC transporter permease	NA	NA	NA	NA
WP_014149469.1\|3529874_3530855_-	ABC transporter permease	NA	NA	NA	NA
WP_046061620.1\|3530890_3533029_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014149471.1\|3533403_3534186_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_014149472.1\|3534601_3536464_-	SurA N-terminal domain-containing protein	NA	NA	NA	NA
WP_014149474.1\|3537427_3537700_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	3.8e-21	55.1
WP_014149475.1\|3537882_3540300_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	9.4e-220	52.7
WP_014149476.1\|3540613_3541885_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.7e-133	57.3
WP_014149477.1\|3541968_3542616_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.6e-57	56.5
WP_014149478.1\|3542634_3543930_-	trigger factor	NA	NA	NA	NA
WP_014149479.1\|3544403_3546104_+	hypothetical protein	NA	NA	NA	NA
WP_014149481.1\|3546639_3548163_-	nitric oxide reductase transcriptional regulator NorR	NA	NA	NA	NA
WP_014149482.1\|3548527_3549526_+	hypothetical protein	NA	NA	NA	NA
WP_014149483.1\|3549810_3551391_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_014149484.1\|3551387_3552842_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_014149485.1\|3552838_3554029_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_014149486.1\|3555383_3556682_-	adenylosuccinate synthase	A0A285PX35	Cedratvirus	4.8e-69	37.0
WP_014149487.1\|3556695_3557886_-	ATP phosphoribosyltransferase regulatory subunit	NA	NA	NA	NA
WP_014149488.1\|3557985_3558843_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_014149489.1\|3558842_3560027_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_016112

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection