CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP011095	Corynebacterium ulcerans strain 131002, complete genome	2 crisprs	cas1,cas3,cas6e,cas8e,cse2gr11,cas7,cas5,DEDDh,csa3,WYL,DinG	1	15	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011095_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011095_1

27310-27524

TypeI-E

I-C,I-E,II-B

Consensus_repeat	Method
GGAACTACCTCCGCATACGCGGAGAAAAGGT	PILER-CR
GGAACTACCTCCGCATACGCGGAGAAAAG	CRISPRCasFinder
GGAACTACCTCCGCATACGCGGAGAAAAG	CRT

3 spacers

cas2,cas1,cas3,cas6e,cas8e,cse2gr11,cas7,cas5

The CRISPR arrays of NZ_CP011095_1

>merge|NZ_CP011095|1|27310-27524|PILER-CR,CRISPRCasFinder,CRT
GGAACTACCTCCGCATACGCGGAGAAAAGGTGATATCGGCAGCACCTGACAAGGTGAATCCGGGAACTACCTCCGCATACGCGGAGAAAAGGTCGCATCGGTGCGATTGAGACGTGTGAGAGCGGAACTACCTCCGCATACGCGGAGAAAAGATTTCAATTTCCACGCGGTCGGTGAAGATGCCGGAACTACCTCCGCATACGCGGAGAAAAGCT

>NZ_CP011095|1|1|27310-27524|PILER-CR
GGAACTACCTCCGCATACGCGGAGAAAAGGT	GATATCGGCAGCACCTGACAAGGTGAATCCG
GGAACTACCTCCGCATACGCGGAGAAAAGGT	CGCATCGGTGCGATTGAGACGTGTGAGAGC
GGAACTACCTCCGCATACGCGGAGAAAAGAT	TTCAATTTCCACGCGGTCGGTGAAGATGCC
GGAACTACCTCCGCATACGCGGAGAAAAGCT

>NZ_CP011095|1|1|27310-27522|CRISPRCasFinder
GGAACTACCTCCGCATACGCGGAGAAAAG	GTGATATCGGCAGCACCTGACAAGGTGAATCCG
GGAACTACCTCCGCATACGCGGAGAAAAG	GTCGCATCGGTGCGATTGAGACGTGTGAGAGC
GGAACTACCTCCGCATACGCGGAGAAAAG	ATTTCAATTTCCACGCGGTCGGTGAAGATGCC
GGAACTACCTCCGCATACGCGGAGAAAAG

>NZ_CP011095|1|1|27310-27522|CRT
GGAACTACCTCCGCATACGCGGAGAAAAG	GTGATATCGGCAGCACCTGACAAGGTGAATCCG
GGAACTACCTCCGCATACGCGGAGAAAAG	GTCGCATCGGTGCGATTGAGACGTGTGAGAGC
GGAACTACCTCCGCATACGCGGAGAAAAG	ATTTCAATTTCCACGCGGTCGGTGAAGATGCC
GGAACTACCTCCGCATACGCGGAGAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011095.1\|WP_046095323.1\|36547_37582_-\|transposase	unknown	unknown	gnl\|CDD\|226202
NZ_CP011095.1\|WP_052716810.1\|27014_27281_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011095.1\|WP_023634795.1\|32500_34111_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cls000721_cas8e_CAS-I-E	unknown
NZ_CP011095.1\|WP_023634788.1\|23422_23734_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011095.1\|WP_014525091.1\|27911_28865_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP011095.1\|WP_046095319.1\|28861_31555_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP011095.1\|WP_046095322.1\|34700_35768_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP011095.1\|WP_046095320.1\|31575_32286_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09727_cas6e_CAS-I-E	gnl\|CDD\|187858
NZ_CP011095.1\|WP_046095318.1\|27539_27911_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
NZ_CP011095.1\|WP_013910428.1\|18467_19004_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223725
NZ_CP011095.1\|WP_046095316.1\|24387_25461_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368892
NZ_CP011095.1\|WP_023634787.1\|22889_23276_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011095.1\|WP_046095315.1\|23828_24401_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011095.1\|WP_046095321.1\|34107_34701_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0096_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP011095.1\|WP_013910437.1\|25691_25919_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375921
NZ_CP011095.1\|WP_046095312.1\|17686_18391_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011095.1\|WP_080940674.1\|35779_36472_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP011095.1\|WP_046095324.1\|37997_38921_+\|phospholipase-D	unknown	unknown	gnl\|CDD\|176518
NZ_CP011095.1\|WP_046095313.1\|19087_19828_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NZ_CP011095.1\|WP_046095314.1\|20881_22810_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380076

Protein	Function_ID	Function_description	E-value
NZ_CP011095.1\|WP_046095323.1\|36547_37582_-\|transposase	gnl\|CDD\|226202	COG3677, COG3677, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00365436
NZ_CP011095.1\|WP_046095316.1\|24387_25461_-\|hypothetical-protein	gnl\|CDD\|368892	pfam06414, Zeta_toxin, Zeta toxin. This family consists of several bacterial zeta toxin proteins. Zeta toxin is thought to be part of a postregulational killing system in bacteria. It relies on antitoxin/toxin systems that secure stable inheritance of low and medium copy number plasmids during cell division and kill cells that have lost the plasmid.	0.000171248
NZ_CP011095.1\|WP_046095324.1\|37997_38921_+\|phospholipase-D	gnl\|CDD\|176518	cd08576, GDPD_like_SMaseD_PLD, Glycerophosphodiester phosphodiesterase-like domain of spider venom sphingomyelinases D, bacterial phospholipase D, and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase-like domain (GDPD-like) present in sphingomyelinases D (SMases D) (sphingomyelin phosphodiesterase D, EC 3.1.4.4) from spider venom, the Corynebacterium pseudotuberculosis Phospholipase D (PLD)-like protein from pathogenic bacteria, and the Ajellomyces capsulatus H143 PLD-like protein from ascomycetes. Spider SMases D and bacterial PLD proteins catalyze the Mg2+-dependent hydrolysis of sphingomyelin producing choline and ceramide 1-phosphate (C1P), which possess a number of biological functions, such as regulating cell proliferation and apoptosis, participating in inflammatory responses, and playing a key role in phagocytosis. In the presence of Mg2+, SMases D can function as lysophospholipase D and hydrolyze lysophosphatidylcholine (LPC) to choline and lysophosphatidic acid (LPA), which is a multifunctional phospholipid involved in platelet aggregation, endothelial hyperpermeability, and pro-inflammatory responses. Loxosceles spider venoms' SMases D are the principal toxins responsible for dermonecrosis and complement dependent haemolysis induced by spider venom. Due to amino acid substitutions at the entrance to the active-site pocket, some members lack activity. The typical GDPD domain consists of a TIM barrel and a small insertion domain named as the GDPD-insertion (GDPD-I) domain, which is specific for GDPD proteins. Although proteins in this family contain a non-typical GDPD domain which lacks the GDPD-I, their catalytic mechanisms are based on Mg2+-dependent acid-base reactions similar to GDPD proteins. They might be divergent members of the GDPD family. Moreover, this family does not belong to phospholipase D (PLD) superfamily, since it lacks the conserved HKD sequence motif that characterizes the catalytic center of the PLD superfamily. It belongs to the superfamily of PLC-like phosphodiesterases.	1.43029e-84
NZ_CP011095.1\|WP_014525091.1\|27911_28865_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.07933e-71
NZ_CP011095.1\|WP_046095319.1\|28861_31555_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	4.25424e-54
NZ_CP011095.1\|WP_046095322.1\|34700_35768_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	8.12809e-81
NZ_CP011095.1\|WP_046095320.1\|31575_32286_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	1.06394e-34
NZ_CP011095.1\|WP_046095318.1\|27539_27911_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	7.87367e-22
NZ_CP011095.1\|WP_013910428.1\|18467_19004_+\|peptidylprolyl-isomerase	gnl\|CDD\|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	6.99746e-66
NZ_CP011095.1\|WP_080940674.1\|35779_36472_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.28176e-26
NZ_CP011095.1\|WP_046095321.1\|34107_34701_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	7.27671e-08
NZ_CP011095.1\|WP_013910437.1\|25691_25919_-\|hypothetical-protein	gnl\|CDD\|375921	pfam18495, VbhA, Antitoxin VbhA. VbhT is a bacterial Fic protein of the mammalian pathogen B. schoenbuchensis7,8. It is composed of an N-terminal FIC domain and a C-terminal BID domain. FIC domains are known to catalyse adenylylation (also called AMPylation). This entry represents VbhA, an antitoxin that binds FIC domain (filamentation induced by cyclic AMP) of VbhT and inhibits its activity. It inhibits the adenylylation activity of VbhT by positioning close to the putative ATP-binding site, hence competing with ATP binding.	0.000240551
NZ_CP011095.1\|WP_046095313.1\|19087_19828_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	8.69582e-22
NZ_CP011095.1\|WP_046095314.1\|20881_22810_+\|hypothetical-protein	gnl\|CDD\|380076	pfam17961, Big_8, Bacterial Ig domain. This entry represents a bacterial Ig-fold domain that is found in a wide range of bacterial cell surface adherence proteins.	3.80617e-10

>NZ_CP011095.1|WP_052716810.1|27014_27281_-|hypothetical-protein
MQDYTDRFNTNAFIEPSTTKIYQSRSGAKARADLLESFGYKAIVQRSAPLVWPEGDNTTVKTTKINEVFAAIKTLVNHGVVKSADELL
>NZ_CP011095.1|WP_013910437.1|25691_25919_-|hypothetical-protein
MDMMNPTERISEDQLRQIRNDLASAEIEGQPRTPEDEKILAAYYLGEISEQESFESLLKAAGVHPPYPSINHDLD
>NZ_CP011095.1|WP_046095316.1|24387_25461_-|hypothetical-protein
MGMVDAPEGMSPMEAAGLIHAESGDIADVVTKMALADGKNVIFDITMTTSGSVTGRIKKAKAHGYDEFTGVYVDVPLEVSLKSAQERYIRGAQEYTDGVGYGGRYVPESAIMRAQVPGSDKTRNRQVFEELTASKVFTATEIWDNNRQDENGNRQPAALIERTTINGKEHHPAVRSGGSDDGRRETSTRQRTTESENKLRRDPSDRGRSLPGRSTDQDSGSGNVREITEKDAERNVQPHTGNEHLNQTPLAAQTSPVVPTTGHYKGKTVHNIDNTDDILKGHDLPEGMTAVIGEYGEIALKFPNKESEREYRKKHGKNFLNVTTGAQAALHDAVKNNDAIPASFFTYTEVTVPVGWV
>NZ_CP011095.1|WP_046095315.1|23828_24401_-|hypothetical-protein
MDGCKDFTCLIPMRTVWVVAEFFRLIFSFLTAENVIFSFLSKENVVFSSSYRQRKRLEHLKFLDEALEREWEKDDEESIKKQIKEIEGKFSGKHWARQPSWMEVAIAGAMITSLTLIVSGAIFFVSHILSEYILRENGWEQGGVLALELRVLIIGILLFLIIVLSAPILLDWPGSKAPDTRKKKKKWGKH
>NZ_CP011095.1|WP_023634788.1|23422_23734_-|hypothetical-protein
MISDSIYKRIKRATGGKVFYGVGVSPENQDNIALDAGYVEALLEYGYLDISLKQEFLELWLTDDEYEDLEALDYVQDLTYKMLLKYADMAPHVDVSHFLKEKS
>NZ_CP011095.1|WP_023634787.1|22889_23276_-|hypothetical-protein
MTNTFTALTERGEGWWVIQLKEDPGLLTQTRRLDQIPDMVRDALELFPELTDDPENAIVNIEFREGESIADIANQAVQANQKAKQAQEEASQLMRQAAAELSKKGLSYRDIGTLLGISFQRAQKLATT
>NZ_CP011095.1|WP_046095314.1|20881_22810_+|hypothetical-protein
MENMSFPARSQRAGKLLCVVACVIALVSSLMVLATGQPLARAEAVCSGGNWSDLAWKDEHSNPSLRDNTYHGPGSHAEVQFEWKAKADAKQGDKITFTLPPQLQGVDTGSILLQDSKNELVARGSWDSGRKSFVITLEQFANTHFNVQGTAFVSVKWNRDGINGDPKKFDGSLSFNGCGHGSLNGKYEEGSEGDSHETVKIGEYRGYDSENKVHKVQWTVGLSGKTGNGQRVLVTDNAPAGWHFACDGKYNDGYAPVYVSSFIKGDPSGEKRHQIFNAQNFDTGGVRYGFGDSIKNDDGFLAGHSYKLNCTPQQVSVELPYGISPNSSPLISLLTISTEKPALGSTVYNTAEVNGKNISGSVTFPSAGGQGRGSKGGFTIEKIVSGEHTSKQFSFEWSCTSQGKETKSGTIKLANGDVHHEKQLDKGASCVIKEEDADAASEKKHSLKWSVDGEDKEGESVTISIRQPEEQAVQVVATNIYYQEEPEIPPAPPTTTSSSSPSTTTSTETTTKTTTTTTTATKTTEPSATTTTSTPPSSPRTTEPTRAPRNPLLPIPIPIPIPLPPAPPVTTTVTPHAPAPVPPPATPSIASNKPADAAPKPPAKRLLARTGASVAGLVIPALFLMIGGVGLLMIIRRKRNSE
>NZ_CP011095.1|WP_046095313.1|19087_19828_+|rhomboid-family-intramembrane-serine-protease
MSAQRTFRAAYNQAPATVILSLSTLIIFLITAVQSRSITDNLYDSWLGDHWILYTPQMHDPLGMLRAIGSMFLHIGPAHLAINLFLLFFLGREVEQFMGSAFFSAAYFISGLGASLTIMILDPLSPTAGASGAIYGLMAIMVAIAITRKTDIRAPLILVAVNVGYSLITDNVSLWGHIGGLIAGAIVALPLMAAHRSHFVAGGFLAYATPRTRRHSPRGQLITWLIVALIAVCEVIGIWVAGTRLL
>NZ_CP011095.1|WP_013910428.1|18467_19004_+|peptidylprolyl-isomerase
MMVRMTLKTATAILHTNRGDVAIELFGNHAPKTVENFVTLADGSADYKTENASGNAEGPFYDGAVFHRVIDGFMIQGGDPTGTGRGGPGYMFADEFHPELQFDRPFLLAMANAGPGTNGSQFFITVVPTPHLNNHHTIFGEVTDPASQKVVMDIAQTATDRMDRPVEPVVIESVEITE
>NZ_CP011095.1|WP_046095312.1|17686_18391_-|hypothetical-protein
MNSSTIRGAVLVTKAAYDKYANYRDRKTREAYDALLNAADSYDDVRKDVKSNVADLYDQSQERVSSLTAQARKRLDSAIADAAAAKDDTVKTVNKQASKASKSLSKQSKKAQKAARKAAQSAKKSATPKKQPSCGKRLFNFSLFTTLLAAVGAVVYYFLSKRDVVSTEPPRVEDFGADSVNTEESRLVYSTHTPVDGEDEHVASPEEGATERDEELLGSLEDQLKQHTDSQEDK
>NZ_CP011095.1|WP_046095318.1|27539_27911_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MFAVIQGHNLPNHLNGYLSRFLSEVDAGLYVGVLSRAVMENLWEKCQSVDLAGSLTLIHPQYDAEQGFRIRTTGKQRRPVVDIDGLFLSARGLIEDVRFTDPLDEADAIIPDEVLEDFCPESE
>NZ_CP011095.1|WP_014525091.1|27911_28865_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MSYSNEALAFSTIPASEQIRLEDRVSFLYLEYCLIRQDRTGVIAVSRGDEKAPAELKDLPIKARIQLPVGGLAVLMLGPGTSISQPAATSCARAGVSVLFTGGGGVQAYSLSTPLTSSARWAIAQARLASNEAKQRTAARILYKRQLGIEEIEADSIAVMRGIEGRTIRNLYKRLSAQHKIKNFKRDTNATDPVNTNLNLGNSILYGCAASACAALGINPALGIIHRGDIRSLLFDLADLYKPTLTIPAAFKCANNDDDGSEFRRLVRSEIVNQDLLKNMIHIMMEILTPHLPERTDDRLIGGRNHEVPGHTQYGGK
>NZ_CP011095.1|WP_046095319.1|28861_31555_-|CRISPR-associated-helicase/endonuclease-Cas3
MTNAGTNHHVLWAKFDNVSEPYPLLAHLLDTATAATCLFNHWLRKGLRDRLSTELGPDAEKILGFVAGIHDLGKANPYFQAQRRNKKEEWITLRDAIQKAGFPLSNGTSALFEETKEKRRHENITLSILGWEITKFLQVKDVWPQLAIIGHHGNFSAPGFLSDEDDLEDIEDIFDDNGWSPTHELLVSSLLQAVGLEKQPEIRHISPASAILISGLVVLADRIASQSEMADNGLQALQKEELFFHQPEKWIANRKAFCCEIIENTVGTYHPWESETAGIRAVLGDYEPRFTQKAALNAGDGLFNVMETTGAGKTEAALLRHVKRKERLLFFLPTQATTNAIMERIGKIFDGTPNVASLAHGLAVTEDFYAHPIVPVRGSSDDANYKDNGGLYPTEFVRSAGTPRLLAPVCVGTIDQALMGALPSKFNHLRLLALANAHVVVDEVHTMDQYQSELMSGLLEWWSATDTPVTLLTATMPAWQREKFHLSYTGKDPHFKGVFPSLEDWSTPSKNTETSQENIPTEAFTIPIRIDKIAHNEIVDSHVQWVIEQRKLFPQARIGIICNTVGRAQSIAEALAHESPIVLHSRMTAGHRKEAATKLEQAIGKKGTATATLVIGTQAIEASLDIDLDLLRTELCPAPSLIQRAGRLWRRLDPQREVRVPGMVGKKLTIAVVDSPSTGQTLPYLRSQLYRVESWLKQRDRIEFPADIQDFIDATTPGLQELFQKVSLPEDCGSAEERETLADDYLNEVASWVTKQRQAGTSRIDFAKHGKPRQVLASDCVVEDFLQITSAKDLEERATRLIDYPTISAILCDPTGTIPGAWTDSVEKLIAISAKDSESLRRALRASISIPHSKKFLPITSREIPLSEAKTLLSGYSAVHIQPDEYDLQSGLKGPQK
>NZ_CP011095.1|WP_046095320.1|31575_32286_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MPNTIYWTSFPAHIALNKSLVLGDSATKDSKTKPRWDVDDPVFRHRAVMALFPEHQSDNARADSNILFRLEALPGQPPYFFVQSSIEPSNHNLDNHIKIRQVDLVSPEAGTPIEFRLSINAVRRKTIDATENTKRKIKTTCLSLKALDSDPTETAAGQWVKEKLSPALENIDIVRHGRQVLGANRNGEKTSNRTVQVDTIDGFAHVKDPAELQKILIHGIGRAKSYGCGMLTFRPI
>NZ_CP011095.1|WP_023634795.1|32500_34111_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MKSNVFKDFPFVKTNKGPMTVEEFFHSSHEESLHLDLSIPGYEYGAIWRLLASLTAVIVQRDPSLLERGESGSELRIDPEFISQILDDLGSKISLTEGKNLFFQRPLLEGENPKDTARYVGPGKDPAWKLSPTAPSEKSQIYWNLEKLKPESLEAVDAIVALMVFSMYSFTGNSKYDGAKCLNGSPGIRFLGGGNTATEFIIESKTPLLSLLKSTPLEWCEPSGLPAWLDRTGAESRKPNGEMHPLWRATWSSNTAACCWDGETLIGVGIGGIPPEWYALEMGSKPEARKEWWDQRNTEDPFYFYQPDKGGALKAKRLDLSRDLTELAVEWVAEDLSTALAERVRGRALRVDFKEDSLLFIRHQIGGNASSAMIRESVVSQARKQQWVFDPTGALQKQVRGKADFILSLRNIVLSPFRRENKSDRDRGRRVLDNLASERPKMNETFWREIAPIYEEFILYFTEQVSGDETRKEVRAQAKKTLKELEKDAVRTAQKAFDMVLEPYLLQNPSQAYEVRRRIHSYLASKIAEANEGDQK
>NZ_CP011095.1|WP_046095321.1|34107_34701_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTTNRPKQPWTPLVAEFAQRKKDKEFRAKRSALRAGSGIYTEFRAYSYVLPFLGEKASEAQRTALLRCMAALAEYPDIVSSGEKATASSVGQWVNSVAFDGKQGQSEPDSMVASRIKYLHTQDLEEAISSLRRIMAFADRKNMAIKLNPYQFVELFWYWGNGFTDASTKHRLSVLRDFYSTKQEENTDPQISSEGEK
>NZ_CP011095.1|WP_046095322.1|34700_35768_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSRHLTIHVVASVPYSNLNRDDSGTPKNVRRGGVTCALLSSQSIKKGIRTKYEDASLDTSVRSGRIADDVLERAKVLAPEADTKALEKAVKKIIGTLTKVAEANESEGESDRSIWLSAEELEAAAVSVVEQAEKKDFIEDGRTGSLAIAAFGRMFAAAPQKGTEAALSVSPAVTTHGVTIATDYFSTVDDIRERNRDTGATYLGVSQYTTGVFYRTVTIDKEQLRESWTGLDREDAKENLAALVNAIIYGLPRGKQHSTAPFVQPALILAEEQSYRCAYDFESPVQADTREGGYLKPTLEELKRQYDSARAFDADNFGETQVVSGTYPEVSEFFACAKYADKNGFIDEVVAWIQR
>NZ_CP011095.1|WP_080940674.1|35779_36472_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTTTSVYLRLAGPLQSWAGPAVTGNFVRTKPIPTHSALVGLIAGAFGYRRDEWPDWLNRLNFRVRVDHPGKFVDDFQTVSAHEEEMLFRERLILATGKRPSAKTTRLTPDGRGMTSIIQRTYLAEAEFIVEVASDTHGELLRDALRAPKFSTYLGRKAFAPAFPFYLGATTDVDVLHRIPACDLSGAKRDTARVQIHHCSAELHTSAEHINVPAVQERSDWLEKTKALFA
>NZ_CP011095.1|WP_046095323.1|36547_37582_-|transposase
MASHPYGHHCDICGSVVKKNGKTSAGKTRYRCTGCGASSTAMRSGTLHQRQMKAFISWILGGKPRDKSDVSRTQRRLMSWCWQVPVPQPSMEDKACILVMNEGTFFQSWCLVVAYNSTHVLGWQWVRKDDKTTCAQVYTYFPRPSAAVISGDESTAQAIQSLWPGIPMRRCLSSIKESVDQKISHTPHTQPAIEIKNLTDSLSYVYTSEQAQLWLDRYNTWETTWKELLKHRTASPNPNHNENSCGWQWTYKELRSIRLMYRTLIKKEELFFQFTAPAIPLSDAALPCQTSLLGDDLSADIKKLFHTHRGINHEHARRMVEWYLNSKTESPFIPERIIKHDHWE
>NZ_CP011095.1|WP_046095324.1|37997_38921_+|phospholipase-D
MKKKVVLFLSIIMGILLPVGNAVATPVSHDAASTGNRPVYAIAHRVLTTQGVDDAVAIGANALEIDFTAWRGGWWADHDGIPTSAGATAEAIFKHIAEKRKQGANITFTWLDIKNPDYCTDPDSVCSINALRDLARKYLEPAGVRVLYGFYKTVGGPGWKTITSDLRHNEAVALSGPTRDVLNDFAKAGDKILTKQKIADYGYYDINQGFGDCYGDGNKTCDQLRKSSEARDQGKLGKTFGWKITTGQDDRVNDLLGKAHVDGMIFGFKVTHFYRHADTENSFKAIKTWVDKHSDTHHLATAADNPW

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Crispr_ID: NZ_CP011095_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011095_2

1891938-1893066

Orphan

I-C,I-E,II-B

Consensus_repeat	Method
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	CRISPRCasFinder
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	CRT
GAACTACCTCCGCATACGCGGAGAAAA	PILER-CR

18 spacers

DinG

The CRISPR arrays of NZ_CP011095_2

>merge|NZ_CP011095|2|1891938-1893066|CRISPRCasFinder,CRT,PILER-CR
ATTTTCTCCGCGTATGCGGAGGTAGTTCATATGGACGTGCCAATCAACCTCAAACCAATTCCTTTTCTCCGCGTATGCGGAGGTAGTTCACTTCCATCCATGCTCTGCCCGTGCGCACGAGGCTTTTCTCCGCGTATGCGGAGGTAGTTCCTTTTAATGCCGAGCTAGTTATGCGTGATCTTTCTTTTCTCCGCGTATGCGGAGGTAGTTCCCCCAGGAAACCCCACAAAAACACGACTCAAATCTTTTCTCCGCGTATGCGGAGGTAGTTCACGGCACCCTAGGTGAAAGCGAAGAGCTGGCGCCCTTTTCTCCGCGTATGCGGAGGTAGTTCCGCTGTCTTTTGCGAAATCCAAAAGCGCTGACGCTTTTCTCCGCGTATGCGGAGGTAGTTCCCTACCCACTGTGTTAAGTAGGTGGGAGCCGTGCTTTTCTCCGCGTATGCGGAGGTAGTTCCTGCCCCGCTAGGGGCGTGGGTGGCTGGGTGCTCTTTTCTCCGCGTATGCGGAGGTAGTTCCAATCCCGGTGGTATATAAGCTCGTCTAGCTCGCTTTTCTCCGCGTATGCGGAGGTAGTTCCAAAGGCAATGCACGGATACCCCGCGCTCCGGTCTTTTCTCCGCGTATGCGGAGGTAGTTCCGCCTACAGCTTCCACGGCTGCGTTAGCCGTGTCTTTTCTCCGCGTATGCGGAGGTAGTTCCTACCTCAGGGGCGACTTTAGTGACGCGGAGTCCTTTTCTCCGCGTATGCGGAGGTAGTTCCGAGGTTGTCGGTGTCGCGGCGTCGGTTATCGCCTTTTCTCCGCGTATGTGGAGGTAGTTCCAACACGGGAGTTCCACTCAGTCAGCGTCACCTCTTTTCTCCGCGTATGCGGAGGTAGTTCCGAGACTGACGCGCTCGTATATATGACTAAGCGCTTTTCTCCGCGTATGCGGAGGTAGTTCCGACGACACCAATTGAGGTTGATTCCACCGCTGCTTTTCTCCGCGTATGCGGAGGTAGTTCCAACGTCAGGGGTGGTTTTCCTAGTCCAATCGCCTTTTTCTCCGCGTATGCGGAGGTAGTTCCAGCGGCCCCCTCACCCTGCAAGGCGGTGGAGCCTTTTCTCCGCGTATGCGGAGGTAGCTCA

>NZ_CP011095|2|2|1891938-1893066|CRISPRCasFinder
ATTTTCTCCGCGTATGCGGAGGTAGTTCA	TATGGACGTGCCAATCAACCTCAAACCAATTC
CTTTTCTCCGCGTATGCGGAGGTAGTTCA	CTTCCATCCATGCTCTGCCCGTGCGCACGAGG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	TTTTAATGCCGAGCTAGTTATGCGTGATCTTT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	CCCAGGAAACCCCACAAAAACACGACTCAAAT
CTTTTCTCCGCGTATGCGGAGGTAGTTCA	CGGCACCCTAGGTGAAAGCGAAGAGCTGGCGCC
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GCTGTCTTTTGCGAAATCCAAAAGCGCTGACG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	CTACCCACTGTGTTAAGTAGGTGGGAGCCGTG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	TGCCCCGCTAGGGGCGTGGGTGGCTGGGTGCT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	AATCCCGGTGGTATATAAGCTCGTCTAGCTCG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	AAAGGCAATGCACGGATACCCCGCGCTCCGGT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GCCTACAGCTTCCACGGCTGCGTTAGCCGTGT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	TACCTCAGGGGCGACTTTAGTGACGCGGAGTC
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GAGGTTGTCGGTGTCGCGGCGTCGGTTATCGC
CTTTTCTCCGCGTATGTGGAGGTAGTTCC	AACACGGGAGTTCCACTCAGTCAGCGTCACCT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GAGACTGACGCGCTCGTATATATGACTAAGCG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GACGACACCAATTGAGGTTGATTCCACCGCTG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	AACGTCAGGGGTGGTTTTCCTAGTCCAATCGCC
TTTTTCTCCGCGTATGCGGAGGTAGTTCC	AGCGGCCCCCTCACCCTGCAAGGCGGTGGAGC
CTTTTCTCCGCGTATGCGGAGGTAGCTCA

>NZ_CP011095|2|2|1891938-1893066|CRT
ATTTTCTCCGCGTATGCGGAGGTAGTTCA	TATGGACGTGCCAATCAACCTCAAACCAATTC
CTTTTCTCCGCGTATGCGGAGGTAGTTCA	CTTCCATCCATGCTCTGCCCGTGCGCACGAGG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	TTTTAATGCCGAGCTAGTTATGCGTGATCTTT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	CCCAGGAAACCCCACAAAAACACGACTCAAAT
CTTTTCTCCGCGTATGCGGAGGTAGTTCA	CGGCACCCTAGGTGAAAGCGAAGAGCTGGCGCC
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GCTGTCTTTTGCGAAATCCAAAAGCGCTGACG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	CTACCCACTGTGTTAAGTAGGTGGGAGCCGTG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	TGCCCCGCTAGGGGCGTGGGTGGCTGGGTGCT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	AATCCCGGTGGTATATAAGCTCGTCTAGCTCG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	AAAGGCAATGCACGGATACCCCGCGCTCCGGT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GCCTACAGCTTCCACGGCTGCGTTAGCCGTGT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	TACCTCAGGGGCGACTTTAGTGACGCGGAGTC
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GAGGTTGTCGGTGTCGCGGCGTCGGTTATCGC
CTTTTCTCCGCGTATGTGGAGGTAGTTCC	AACACGGGAGTTCCACTCAGTCAGCGTCACCT
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GAGACTGACGCGCTCGTATATATGACTAAGCG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	GACGACACCAATTGAGGTTGATTCCACCGCTG
CTTTTCTCCGCGTATGCGGAGGTAGTTCC	AACGTCAGGGGTGGTTTTCCTAGTCCAATCGCC
TTTTTCTCCGCGTATGCGGAGGTAGTTCC	AGCGGCCCCCTCACCCTGCAAGGCGGTGGAGC
CTTTTCTCCGCGTATGCGGAGGTAGCTCA

>NZ_CP011095|2|2|1891939-1893004|PILER-CR
TTTTCTCCGCGTATGCGGAGGTAGTTC	ATATGGACGTGCCAATCAACCTCAAACCAATTCC
TTTTCTCCGCGTATGCGGAGGTAGTTC	ACTTCCATCCATGCTCTGCCCGTGCGCACGAGGC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CTTTTAATGCCGAGCTAGTTATGCGTGATCTTTC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CCCCAGGAAACCCCACAAAAACACGACTCAAATC
TTTTCTCCGCGTATGCGGAGGTAGTTC	ACGGCACCCTAGGTGAAAGCGAAGAGCTGGCGCCC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CGCTGTCTTTTGCGAAATCCAAAAGCGCTGACGC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CCTACCCACTGTGTTAAGTAGGTGGGAGCCGTGC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CTGCCCCGCTAGGGGCGTGGGTGGCTGGGTGCTC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CAATCCCGGTGGTATATAAGCTCGTCTAGCTCGC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CAAAGGCAATGCACGGATACCCCGCGCTCCGGTC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CGCCTACAGCTTCCACGGCTGCGTTAGCCGTGTC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CTACCTCAGGGGCGACTTTAGTGACGCGGAGTCC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CGAGGTTGTCGGTGTCGCGGCGTCGGTTATCGCC
TTTTCTCCGCGTATGTGGAGGTAGTTC	CAACACGGGAGTTCCACTCAGTCAGCGTCACCTC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CGAGACTGACGCGCTCGTATATATGACTAAGCGC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CGACGACACCAATTGAGGTTGATTCCACCGCTGC
TTTTCTCCGCGTATGCGGAGGTAGTTC	CAACGTCAGGGGTGGTTTTCCTAGTCCAATCGCCT
TTTTCTCCGCGTATGCGGAGGTAGTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011095.1\|WP_013912192.1\|1895339_1897061_-\|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|238832
NZ_CP011095.1\|WP_052716831.1\|1893116_1893614_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|259851
NZ_CP011095.1\|WP_046096243.1\|1882592_1883360_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293802
NZ_CP011095.1\|WP_023636163.1\|1883432_1884326_-\|glutamate-racemase	unknown	unknown	gnl\|CDD\|234851
NZ_CP011095.1\|WP_155392581.1\|1894129_1894285_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011095.1\|WP_032802901.1\|1885941_1886241_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP011095.1\|WP_014836727.1\|1898954_1899440_+\|ferritin	unknown	unknown	gnl\|CDD\|153113
NZ_CP011095.1\|WP_046096244.1\|1884392_1885211_-\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NZ_CP011095.1\|WP_023636175.1\|1901815_1902253_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|179603
NZ_CP011095.1\|WP_046096247.1\|1889854_1890355_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP011095.1\|WP_046096250.1\|1899506_1901666_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236179
NZ_CP011095.1\|WP_046096248.1\|1890351_1891629_-\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NZ_CP011095.1\|WP_046096245.1\|1886446_1887802_+\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236426
NZ_CP011095.1\|WP_046096249.1\|1894852_1895197_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011095.1\|WP_038620771.1\|1885296_1885833_-\|DUF2017-domain-containing-protein	unknown	unknown	gnl\|CDD\|378185
NZ_CP011095.1\|WP_046096246.1\|1887868_1889833_+\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NZ_CP011095.1\|WP_003852698.1\|1903087_1903210_-\|50S-ribosomal-protein-L36	unknown	unknown	gnl\|CDD\|179138
NZ_CP011095.1\|WP_013242528.1\|1902379_1902613_-\|glutaredoxin-like-protein-NrdH	unknown	unknown	gnl\|CDD\|131249
NZ_CP011095.1\|WP_046096242.1\|1881819_1882554_-\|ribonuclease-PH	unknown	unknown	gnl\|CDD\|178914
NZ_CP011095.1\|WP_013912194.1\|1897528_1898515_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027

Protein	Function_ID	Function_description	E-value
NZ_CP011095.1\|WP_013912192.1\|1895339_1897061_-\|cytochrome-c-oxidase-subunit-I	gnl\|CDD\|238832	cd01662, Ubiquinol_Oxidase_I, Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits in ubiquinol oxidase varies from two to five. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme and a copper ion. It also contains a low-spin heme, believed to participate in the transfer of electrons from ubiquinol to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from ubiquinol on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. It is generally believed that the channels contain water molecules that act as 'proton wires' to transfer the protons. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are believed to be transferred directly from ubiquinol (the electron donor) to the low-spin heme, and directly from the low-spin heme to the binuclear center.	0
NZ_CP011095.1\|WP_052716831.1\|1893116_1893614_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|259851	cd00569, HTH_Hin_like, Helix-turn-helix domain of Hin and related proteins. This domain model summarizes a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed helical bundle. The principal DNA-protein interface is formed by the third helix, the recognition helix, inserting itself into the major groove of the DNA. A diverse array of HTH domains participate in a variety of functions that depend on their DNA-binding properties. HTH_Hin represents one of the simplest versions of the HTH domains; the characterization of homologous relationships between various sequence-diverse HTH domain families remains difficult. The Hin recombinase induces the site-specific inversion of a chromosomal DNA segment containing a promoter, which controls the alternate expression of two genes by reversibly switching orientation. The Hin recombinase consists of a single polypeptide chain containing a C-terminal DNA-binding domain (HTH_Hin) and a catalytic domain.	0.000435743
NZ_CP011095.1\|WP_046096243.1\|1882592_1883360_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293802	cd07716, RNaseZ_short-form-like_MBL-fold, uncharacterized bacterial subgroup of Ribonuclease Z, short form; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. Members of this bacterial subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	5.97988e-76
NZ_CP011095.1\|WP_023636163.1\|1883432_1884326_-\|glutamate-racemase	gnl\|CDD\|234851	PRK00865, PRK00865, glutamate racemase; Provisional.	3.90227e-133
NZ_CP011095.1\|WP_032802901.1\|1885941_1886241_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	7.46567e-37
NZ_CP011095.1\|WP_014836727.1\|1898954_1899440_+\|ferritin	gnl\|CDD\|153113	cd01055, Nonheme_Ferritin, nonheme-containing ferritins. Nonheme Ferritin domain, found in archaea and bacteria, is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The ferritin protein shell is composed of 24 protein subunits arranged in 432 symmetry. Each protein subunit, a four-helix bundle with a fifth short terminal helix, contains a dinuclear ferroxidase center (H type). Unique to this group of proteins is a third metal site in the ferroxidase center. Iron storage involves the uptake of iron (II) at the protein shell, its oxidation by molecular oxygen at the ferroxidase centers, and the movement of iron (III) into the cavity for deposition as ferrihydrite.	9.84725e-59
NZ_CP011095.1\|WP_046096244.1\|1884392_1885211_-\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	1.59074e-22
NZ_CP011095.1\|WP_023636175.1\|1901815_1902253_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|179603	PRK03600, nrdI, class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI.	2.7764e-75
NZ_CP011095.1\|WP_046096247.1\|1889854_1890355_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.59839e-27
NZ_CP011095.1\|WP_046096250.1\|1899506_1901666_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236179	PRK08188, PRK08188, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_CP011095.1\|WP_046096248.1\|1890351_1891629_-\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.02844e-95
NZ_CP011095.1\|WP_046096245.1\|1886446_1887802_+\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
NZ_CP011095.1\|WP_038620771.1\|1885296_1885833_-\|DUF2017-domain-containing-protein	gnl\|CDD\|378185	pfam09438, DUF2017, Domain of unknown function (DUF2017). This is an alpha-helical domain found in gene neighborhoods that contain genes encoding ubiquitin, cysteine synthases and JAB peptidases.	1.83085e-72
NZ_CP011095.1\|WP_046096246.1\|1887868_1889833_+\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	2.57189e-152
NZ_CP011095.1\|WP_003852698.1\|1903087_1903210_-\|50S-ribosomal-protein-L36	gnl\|CDD\|179138	PRK00831, rpmJ, 50S ribosomal protein L36; Validated.	1.69298e-09
NZ_CP011095.1\|WP_013242528.1\|1902379_1902613_-\|glutaredoxin-like-protein-NrdH	gnl\|CDD\|131249	TIGR02194, Glutaredoxin-like_protein_NrdH, Glutaredoxin-like protein NrdH. NrdH-redoxin is a representative of a class of small redox proteins that contain a conserved CXXC motif and are characterized by a glutaredoxin-like amino acid sequence and thioredoxin-like activity profile. Unlike other the glutaredoxins to which it is most closely related, NrdH aparrently does not interact with glutathione/glutathione reductase, but rather with thioredoxin reductase to catalyze the reduction of ribonucleotide reductase.	1.51252e-32
NZ_CP011095.1\|WP_046096242.1\|1881819_1882554_-\|ribonuclease-PH	gnl\|CDD\|178914	PRK00173, rph, ribonuclease PH; Reviewed.	1.29549e-163
NZ_CP011095.1\|WP_013912194.1\|1897528_1898515_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0

>NZ_CP011095.1|WP_046096248.1|1890351_1891629_-|phosphoserine-phosphatase-SerB
MIELDQPQVTVSLRPELTPAVITISGQDRQGVSAAAFRVLAANGVQILDVEQSQFRGFLGLAVFAGVEAAGVETLEIGLKETLKTYGQSVKIELQEVAQSSRPRSTHEVVILGDPVEAHDLSRIAQTLANFDANIDTIRGISDYPVTGLELKITVANREPGAAMPLRKALAELTTELGVDIAIERAGLLRRSKRLICFDCDSTLITGEVIEMLAAHAGREKEVAEVTERAMRGELDFEESLRERVKALAGLDASVIDEVADSIELTPGARTTIRTLKRLGYKTAVVSGGFIQVLEGLAEDLGLDYVRANTLEIVDGKLTGRVIGKVVDRAAKAEFLEEFARESGIEMHQTVAVGDGANDIDMISAAGLGIAFNAKPALREIADTSVNSPFLDEVVHMLGITRADIDAADDSDGKIRRVPLPQQKN
>NZ_CP011095.1|WP_046096247.1|1889854_1890355_+|GNAT-family-N-acetyltransferase
MAHIPTLRNESIRLRPLLLSDAHDLTATCVDPLTQKYTTIPAGYTLANAEEFITTEHDNLRWVITTRTSDRFCGQIELRPLAGEHNAMDVGYMTAPWARGQGLMTSALLLAVDYALSLGVHRIELRTDPQNKASQRVAEKAGFLYQGLHNDFTVYSLLADDYRSSY
>NZ_CP011095.1|WP_046096246.1|1887868_1889833_+|ATP-dependent-DNA-helicase
MSDSPLALSTDELLDAAVAALGGSRRNGQVSMANAVTKALESERHLAVQAGTGTGKSLAYLVPALRHAQATDSTIIVSTATIALQRQLVERDLPRLADALEPHMSRRPTFAIMKGRANYVCMNKIAAAEEPEDALIDEEDLSWLGKHVARIYEWANETEVGDRDSLDPGVPDLAWRQVSVSAQECIGASRCPHGEDCFAEIARKKTHDVDVIVTNHALLAIDALSDVNVLPEHEVVIVDEAHELDGRITAVATNEIGVTALTMSSRRAGKLGAGDKDQKLIDISKEWEDAMLAVEPGRLTSLPESLKQQTTALRDAIWSLREHVSRVPEGEAANDPERHAERMSLSNHLGDQHDSVVRILSVFEEEDAASQEDVVWVLHDDRRGVMIKVAPLSIAGLLHTRLFSENTVVLASATLNIGGNFNAMAASWGLPKGSWDSLDAGTPFDPAKSGILYTPNSLPDPGRDGLSPEVIEEIYDLIMAAGGRTLGLFSSRRAAQQATEAMRTRLPFDVLCQGDDTTGALVEKFSKQENTCLFGTLSLWQGVDVPGKACSLVIIDRIPFPRPDDPLLQARKDAADAEGRNGFMEVAATHAALLIAQGAGRLLRSVTDRGVVAILDRRIVTKRYGAFFIKSLPAFWRTNDPQVVRGALARLVAK
>NZ_CP011095.1|WP_046096245.1|1886446_1887802_+|nicotinate-phosphoribosyltransferase
MTCASALIVFKAKLVCVTEFESTALLTDMYELTMLQSALADGTAYRNCTFEVFSRRLPNERRYGVVAGTARVLEAVKRYRFTEKQLASLTFLDATTIDFLRSYEFKGQIDGYREGELYFPSSPILTIRGTFAECVILETLILSIMNADSAVASAAARMVTAADGRPIFEMGSRRTHEYAAVTAARAAYLAGFVGTSNLEAVYRYGIPGSGTAAHAWTLLHVNDDGTPNEPAAFQSQINVLGVGTTLLVDTYDIAKGVKTAIEIAGPQLGAVRIDSGDLGVMTRKVRQELDSLGAHNTGIVVSSDLDEYAIAGLRGNPVDAFGVGTSVVTGSGAPTAGMVYKLVEVDGHPVAKRSRGKAMVGGTKRAVRTHRATGTAVEEIVFPYDHDAPQIGQLNSYELTIPLMRNGIVVDNLPTLEESRAYLAEQLITLPWEGLALSKDEPVLSTRFVGF
>NZ_CP011095.1|WP_032802901.1|1885941_1886241_-|ATP-dependent-Clp-protease-adapter-ClpS
MSSPMATPELDEDLSVDVASSENLPWMCIVWDDPVNLMSYVTYVFQTILGYSKRRAIELMMQVHTEGKAVVSSGERDKVEGDVKKLHTAGLWATMQQGG
>NZ_CP011095.1|WP_038620771.1|1885296_1885833_-|DUF2017-domain-containing-protein
MQPWKKKKGLMRGAHFVCVFEPMEREVLGNLASTVSEALIHRAQTAPKDELAELTGMPSGHKEAPTDPALARLLPDFEKEGDEEFEGDNSLLRCLHETDITRAKVEHLQVLGQALGPDGGVHVDITEPEAHAWVAALNDIRLYVASGEVFGEEAEQDRDSLVEWLAYNQESLLNAMMG
>NZ_CP011095.1|WP_046096244.1|1884392_1885211_-|rhomboid-family-intramembrane-serine-protease
MELRDFFIRLCLIMTNRFNPYAQSDRNTYGGVSTSGGYLPHEYGAQYLPTPGYSANRVTHRGVSTSSWRSMGRKRLVDATVLALGYVIVIWAVHIVNTVFFGGTLAQGLGVHPLDGASIWHIFTSPLVHGNYMHLSANTLPGLIFVFLIGLSGRRAFWEVTIIAAVVGGMGTWIFGGIGTTHIGASGLIYGWLAYLVVRGIFNRSFSQVLLGMVLAFIYGGLIWGVLPGDVGVSWQAHLFGAIGGLIAGATITSDDPPALKARREQRALERS
>NZ_CP011095.1|WP_023636163.1|1883432_1884326_-|glutamate-racemase
MDYVIQDHMSDSLKADVPGVEPSIVYKGTIDASSPIGIFDSGVGGLTVARAIMEQLPQESVIYIGDTAHSPYGPKPIAQVRELSMRIGDELVARGCKMIVIACNTATSAALRDLRERYSIPVVGVILPAVRRAVATTRNGKIGVLGTQGTIASGAYQELFAASPGVDVYAQACPSFVSFVERGITSGRQILGVAQGYTEGLQAAGVDTLVLGCTHYPLLTGVIQLAVGDNVTLISSSEECVKDVLKTLSRNDMLADATTDKQPIRSFESTGDPALFEQLAMRFLGPHVTHVEKLREV
>NZ_CP011095.1|WP_046096243.1|1882592_1883360_-|MBL-fold-metallo-hydrolase
MKLTILGSSGSLGAPDNAASGYLIQMDNAPSILMDMGPGVLAQLERVQNPSDAHVVFSHLHADHCVDFPSLLVWRRYHPTAAAKGRNLCFGPSDTPIRMGRLSADSVDNIDDMSDTFAFTPWENAREELVGAVSITPYSVVHPIETFALRVEHKRSGKIIAYSGDSSYTENLIECARNADVFLCEATWGETSEGKAPNMHMSGAEAGRIARLAGAKRLILVHIPPWGNAEAALEKARSEYDGPIDISYQGMEINI
>NZ_CP011095.1|WP_046096242.1|1881819_1882554_-|ribonuclease-PH
MTTSNFKRADGRAVDQMRTVKITRGFTTNPAGSVLVEFGNTRVMCTASAEIGVPRFKRDSGEGWLTAEYAMLPAATLDRNPRESMRGKVKGRTHEISRLIGRSLRAAVDLSELGENTINIDCDVLQADGGTRTASITGAYVALADAIAHLQKQGVVPGNPLKDPVAAVSVGVIDGTVCLDLPYEEDSRADVDMNVIMQSGCFVEIQGTGEHNTFDRDELARILDFAEKGCAELVEAQKAVLGIA
>NZ_CP011095.1|WP_052716831.1|1893116_1893614_+|helix-turn-helix-domain-containing-protein
MSIPPEQVMQLLGEGMTQSQIAREYGVTRQYIFILAKRAGHEAAEQEYIKDDLPWADIDETHKDNTIFKALRMHARYMERGQKSLRGSSCVKLLGMYRKLVRFNQVIDYDESYPPVKGLSNTGGFMYVPRSPEDGNLIIKMKPGVRITKRGARIWQLPKKFPEKE
>NZ_CP011095.1|WP_155392581.1|1894129_1894285_-|hypothetical-protein
MKNNIHLAILGLLAASVALGAPRVITYGIAALLFAVLTVKTWSLARAWVKQ
>NZ_CP011095.1|WP_046096249.1|1894852_1895197_+|hypothetical-protein
MQLQTTVTRVLITTTVALSFALASTSTLAHAETKPIPTACQELQADVEAWTEQLKEAESSHDQLSKNGHSKDSIKRYLERSQQYLQECISSPPKPLHFELSSAPPMFMSNLSSS
>NZ_CP011095.1|WP_013912192.1|1895339_1897061_-|cytochrome-c-oxidase-subunit-I
MTAVAPRLENYSEPTRPAPTGGARKGTLAWKMLTTTDHKQLGIMYIIMSFVFFFLGGLMALLIRAELFSPGLQYLSNEQFNQLFTMHGTVMLLLFGTPIVWGFANYILPLQIGAPDVAFPRLNAFGFWVTMIGAAAMLSGFLTPGGAADFGWTMYLPLADSIHSPGIGSDMWIVGVGATGVGTISSAINMITTILCMRAPGMTMFRMPIFCWNIFVASVLVLMIFPLLTAAALGVLYDRKLGGHLFDPGNGGAIMWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFARKPMFGYIGLVFATLSIGSLSMAVWAHHMFVTGAILLPFFSFMTFLISVPTGVKFFNWLGTMWKGHVSWETPMTWTMGFLVTFLFGGLTGIMLASPPLDFHISDTYFVVAHFHYTLFGTVVFASFAGVYFWFPKMTGRMLDERLGKIHFWITFVGFHGTFLVQHWLGNEGMPRRYADYLDSDGFTTLNQISTIFSFLLGMSVLPFIWNVIKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTSLPRIRSERPAFELHYPHMVERMRREAHVGHHAEPVTKKTS
>NZ_CP011095.1|WP_013912194.1|1897528_1898515_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MESYDSYLESHKKPVSAINWNSIPDEKDLEVWDRLTGNFWLPEKVPVSNDLKSWGTLNDLEKTTTMRVFTGLTMLDTIQGTVGAVSMIPDAITPHEEAVYTNIAFMESVHAKSYSNIFMTLASTKEINEAFRWSEENENLQKKAKIVLSYYEGADPLKRKVASTLLESFLFYSGFYLPMYWSSHAKLTNTADIIRLIIRDEAVHGYYIGYKYQQAVRQQTPERQAELKEYTFDLLYDLYDNEIQYTEDLYDDLGWTEDVKRFLRYNANKALNNLGYEGLFPADECKVSPAILSALSPNADENHDFFSGSGSSYVIGKAENTTDDDWDF
>NZ_CP011095.1|WP_014836727.1|1898954_1899440_+|ferritin
MSINEKLAAALNNQITAELEASMVYLQLSYILDDLSLTGMRNWMQAQHKEELDHAAQFSKHLLDRDYRPQIGDIAPPKLDANSAIEAFEASLAHEQKVTAMIRELAEIADSVKDYDSRPLIDRFLEEQIEEEATVKEILDRLRIADTGSGILRIDAELAAR
>NZ_CP011095.1|WP_046096250.1|1899506_1901666_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MSQSLGKHVAEPVSRTEQLDYHALNALLNLYNADGKIQFDKDREAANQFFLQHVNQNTVFFHDLEEKIEYLVENNYYEPEIIQQYEFVFIKDLFKQAYAHKFRFKSFLGAYKYYTSYTLKTFDGRRYLERFEDRVCMVALTLADGDQDLARNLVDEIMTGRFQPATPTFLNSGKAQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNLREAGAPIKKIENQSSGVIPVMKLLEDSFSYANQLGARQGAGAVYLNAHHPDILNFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGKAFADISVSEHYAEMVEDPRIRKSKINAREFFQTIAEIQFESGYPYIMFEDTVNKANPIEGRVNMSNLCSEILQVNTPSLFNDDLTYEEVGEDISCNLGSLNIAMTMDSPDFAKTIETAIRGLTAVSEQTAINSVPSIRKGNDAAHAIGLGQMNLHGYLGREHIYYGSEEGLDFTNAYFAAVLYQCLVASNKLARERGRTFAGFETSKYATGEYFDDFDPADFAPKTEKVAKIFADSSIYTPTAADWADLKDAVAAHGLYNRYLQAVPPTGSISYINHSTSSIHPIASKIEIRKEGKIGRVYYPAPHMDNENLDYFADAYEIGFEKVIDTYAVATKYVDQGLSLTLFFKDSATTRDINRAQIYAWRKGIKTLYYIRLRQVALMGTEVEGCVSCML
>NZ_CP011095.1|WP_023636175.1|1901815_1902253_-|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MLVVYFSSATENTKRFVRKLGFPAKRIPLHKSSPELVVDEPYVLVCPTYGGGASISGGNTRPVPAQVIRFLNNEHNRGLLRAVIAGGNSNFGLDFGKAGDMIAAKCQVPYVYRFELLGTDEDVRLVRDGLLSNAAALGLLPEPVA
>NZ_CP011095.1|WP_013242528.1|1902379_1902613_-|glutaredoxin-like-protein-NrdH
MSITVYTKPACVQCNATKKALDRAGLDYTLVDISIDDEARDYVMALGYLQAPVVEVNGEHWSGFRPERISSLVAQVA
>NZ_CP011095.1|WP_003852698.1|1903087_1903210_-|50S-ribosomal-protein-L36
MKVRKSLRSLKNKPGAQVVRRRGKVYVINKKDPRFKARQG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP011095_2	2.1\|1891967\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1891967-1891998	32	NZ_CP011095.1	972128-972159	0	1.0

1. spacer 2.1|1891967|32|NZ_CP011095|CRISPRCasFinder,CRT matches to position: 972128-972159, mismatch: 0, identity: 1.0

tatggacgtgccaatcaacctcaaaccaattc	CRISPR spacer
tatggacgtgccaatcaacctcaaaccaattc	Protospacer
********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011095_1	1.1\|27341\|31\|NZ_CP011095\|PILER-CR	27341-27371	31	L04258	Corynebacteriophage beta immunity-specific proteins Beta241, Beta201, Beta286, and Beta371 genes, complete coding regions	2394-2424	3	0.903
NZ_CP011095_1	1.2\|27403\|30\|NZ_CP011095\|PILER-CR	27403-27432	30	NZ_CP011543	Corynebacterium mustelae strain DSM 45274 plasmid pCmus45274, complete sequence	16064-16093	5	0.833
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP011543	Corynebacterium mustelae strain DSM 45274 plasmid pCmus45274, complete sequence	16062-16093	5	0.844
NZ_CP011095_2	2.18\|1893006\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1893006-1893037	32	NZ_CP016462	Blastomonas sp. RAC04 plasmid pBSY18_1, complete sequence	132555-132586	5	0.844
NZ_CP011095_1	1.3\|27464\|30\|NZ_CP011095\|PILER-CR	27464-27493	30	NZ_CP054842	Acidovorax sp. 16-35-5 plasmid unnamed2, complete sequence	51136-51165	6	0.8
NZ_CP011095_1	1.3\|27464\|30\|NZ_CP011095\|PILER-CR	27464-27493	30	NZ_CP025613	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence	351865-351894	7	0.767
NZ_CP011095_2	2.11\|1892578\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892578-1892609	32	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	2474290-2474321	7	0.781
NZ_CP011095_2	2.13\|1892700\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892700-1892731	32	NZ_CP032928	Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence	297350-297381	7	0.781
NZ_CP011095_1	1.3\|27464\|30\|NZ_CP011095\|PILER-CR	27464-27493	30	NZ_CP032676	Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence	65159-65188	8	0.733
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	255429-255460	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	275419-275450	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	250767-250798	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	257970-258001	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	255602-255633	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	255972-256003	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	269768-269799	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	255972-256003	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	259037-259068	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	255967-255998	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	275419-275450	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	269768-269799	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	255602-255633	8	0.75
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NC_010998	Rhizobium etli CIAT 652 plasmid pA, complete sequence	261606-261637	8	0.75
NZ_CP011095_2	2.1\|1891967\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1891967-1891998	32	NZ_AP014708	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_4p, complete sequence	34614-34645	8	0.75
NZ_CP011095_2	2.12\|1892639\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892639-1892670	32	NZ_CP049734	Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence	228326-228357	8	0.75
NZ_CP011095_2	2.12\|1892639\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892639-1892670	32	NZ_CP016288	Rhizobium leguminosarum strain Vaf10 plasmid unnamed7, complete sequence	156431-156462	8	0.75
NZ_CP011095_2	2.12\|1892639\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892639-1892670	32	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	921457-921488	8	0.75
NZ_CP011095_2	2.12\|1892639\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892639-1892670	32	CP049734	Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence	17058-17089	8	0.75
NZ_CP011095_2	2.12\|1892639\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892639-1892670	32	NZ_CP030762	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence	258342-258373	8	0.75
NZ_CP011095_2	2.12\|1892639\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892639-1892670	32	NZ_CP050089	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b2, complete sequence	177382-177413	8	0.75
NZ_CP011095_2	2.13\|1892700\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892700-1892731	32	NZ_CP007515	Rubrobacter radiotolerans strain RSPS-4 plasmid 1, complete sequence	59572-59603	8	0.75
NZ_CP011095_2	2.18\|1893006\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1893006-1893037	32	NZ_CP049359	Deinococcus wulumuqiensis R12 plasmid unnamed2, complete sequence	222175-222206	8	0.75
NZ_CP011095_2	2.31\|1892699\|34\|NZ_CP011095\|PILER-CR	1892699-1892732	34	NZ_CP032928	Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence	297349-297382	8	0.765
NZ_CP011095_1	1.5\|27401\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	27401-27432	32	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	274270-274301	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_KP975076	Pseudomonas aeruginosa strain MRSN17623 plasmid pMRVIM0713, complete sequence	11397-11428	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP010958	Sphingobium sp. YBL2 plasmid 4pYBL2-4, complete sequence	39971-40002	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP015373	Pandoraea pnomenusa strain MCB032 plasmid unnamed 2, complete sequence	67720-67751	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	MN336501	Pseudomonas aeruginosa strain 164130 plasmid p4130-KPC, complete sequence	4133-4164	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	73580-73611	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	320338-320369	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP010801	Ralstonia mannitolilytica strain SN82F48 plasmid pRMAN01, complete sequence	103569-103600	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NC_017908	Mycobacterium abscessus subsp. bolletii F1725 plasmid BRA100, complete sequence	50367-50398	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_MN433457	Pseudomonas aeruginosa strain PAB546 plasmid pNK546-KPC, complete sequence	335286-335317	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP046330	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed1, complete sequence	136474-136505	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP046332	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed2	62360-62391	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP026545	Cupriavidus metallidurans strain Ni-2 plasmid unnamed1	12530-12561	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_KU237244	Sphingomonas sp. SH plasmid pSH, complete sequence	34064-34095	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP026974	Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence	64750-64781	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	KM659090	Achromobacter sp. LM16 plasmid pLM16A1, complete sequence	20828-20859	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JX469831	Uncultured bacterium plasmid pKSP212, complete sequence	50070-50101	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	MF344569	Pseudomonas aeruginosa plasmid p12939-PER, complete sequence	307678-307709	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JN106172	Uncultured bacterium plasmid pAKD29, complete sequence	50749-50780	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JN106173	Uncultured bacterium plasmid pAKD31, complete sequence	49868-49899	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JN106174	Uncultured bacterium plasmid pAKD33, complete sequence	53702-53733	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	5312-5343	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	73799-73830	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	561892-561923	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NC_002698	Shigella flexneri 5a virulence plasmid pWR501, complete sequence	202955-202986	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JN106165	Uncultured bacterium plasmid pAKD14, complete sequence	44352-44383	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JN106166	Uncultured bacterium plasmid pAKD15, complete sequence	62278-62309	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JN106168	Uncultured bacterium plasmid pAKD17, complete sequence	47483-47514	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JN106169	Uncultured bacterium plasmid pAKD18, complete sequence	63026-63057	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP026230	Aeromonas sp. ASNIH1 plasmid pKPC-038c, complete sequence	49122-49153	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	MN583270	Pseudomonas aeruginosa strain NK546 plasmid pNK546b, complete sequence	223775-223806	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NC_016978	Comamonas testosteroni plasmid pI2, complete sequence	79932-79963	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP017451	Klebsiella sp. LTGPAF-6F plasmid unnamed1, complete sequence	345472-345503	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP027173	Pseudomonas aeruginosa strain AR_0353 plasmid unnamed1, complete sequence	4006-4037	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	KF743817	Proteus mirabilis plasmid R772, complete sequence	55616-55647	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	KF743818	Bordetella bronchiseptica plasmid R906, complete sequence	52372-52403	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NC_006525	Cupriavidus metallidurans CH34 plasmid pMOL28, complete sequence	141673-141704	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NC_019906	Pseudomonas putida HB3267 plasmid pPC9, complete sequence	68856-68887	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	JX194160	Uncultured bacterium plasmid pM02_c6 clone c6, complete sequence	14221-14252	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NC_009739	Pseudomonas aeruginosa plasmid pMATVIM-7, complete sequence	4133-4164	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NC_006466	Cupriavidus metallidurans CH34 plasmid pMOL30, complete sequence	126664-126695	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NC_021077	Comamonas sp. 7D-2 plasmid pBHB, complete sequence	5463-5494	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP043439	Cupriavidus campinensis strain MJ1 plasmid unnamed2, complete sequence	232326-232357	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_LT882698	Klebsiella pneumoniae strain Klebsiella pneumoniae KLPN57 isolate KLPN57 plasmid I, complete sequence	34476-34507	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_MK851048	Morganella morganii strain MM1L5 plasmid pMM1L5, complete sequence	23430-23461	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_MK851047	Actinobacillus pleuropneumoniae strain APP1L5 plasmid pAPP1L5, complete sequence	40393-40424	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP033834	Pseudomonas aeruginosa strain FDAARGOS_570 plasmid unnamed, complete sequence	23870-23901	9	0.719
NZ_CP011095_2	2.2\|1892028\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892028-1892059	32	NZ_CP048383	Citrobacter freundii strain 62 plasmid p6_A, complete sequence	42901-42932	9	0.719
NZ_CP011095_2	2.8\|1892395\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892395-1892426	32	NZ_CP009295	Novosphingobium pentaromativorans US6-1 plasmid pLA5, complete sequence	10409-10440	9	0.719
NZ_CP011095_2	2.8\|1892395\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892395-1892426	32	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	133051-133082	9	0.719
NZ_CP011095_2	2.10\|1892517\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1892517-1892548	32	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	998759-998790	9	0.719
NZ_CP011095_2	2.31\|1892699\|34\|NZ_CP011095\|PILER-CR	1892699-1892732	34	NZ_CP007515	Rubrobacter radiotolerans strain RSPS-4 plasmid 1, complete sequence	59571-59604	9	0.735
NZ_CP011095_2	2.18\|1893006\|32\|NZ_CP011095\|CRISPRCasFinder,CRT	1893006-1893037	32	NC_041927	Sphingobium phage Lacusarx, complete genome	47407-47438	10	0.688
NZ_CP011095_2	2.30\|1892638\|34\|NZ_CP011095\|PILER-CR	1892638-1892671	34	NZ_CP049734	Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence	228325-228358	10	0.706
NZ_CP011095_2	2.30\|1892638\|34\|NZ_CP011095\|PILER-CR	1892638-1892671	34	CP049734	Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence	17057-17090	10	0.706
NZ_CP011095_2	2.30\|1892638\|34\|NZ_CP011095\|PILER-CR	1892638-1892671	34	NZ_CP030762	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence	258341-258374	10	0.706
NZ_CP011095_2	2.30\|1892638\|34\|NZ_CP011095\|PILER-CR	1892638-1892671	34	NZ_CP016288	Rhizobium leguminosarum strain Vaf10 plasmid unnamed7, complete sequence	156430-156463	10	0.706
NZ_CP011095_2	2.30\|1892638\|34\|NZ_CP011095\|PILER-CR	1892638-1892671	34	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	921456-921489	10	0.706
NZ_CP011095_2	2.30\|1892638\|34\|NZ_CP011095\|PILER-CR	1892638-1892671	34	NZ_CP050089	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b2, complete sequence	177381-177414	10	0.706
NZ_CP011095_2	2.19\|1891966\|34\|NZ_CP011095\|PILER-CR	1891966-1891999	34	NZ_AP014708	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_4p, complete sequence	34613-34646	11	0.676

1. spacer 1.1|27341|31|NZ_CP011095|PILER-CR matches to L04258 (Corynebacteriophage beta immunity-specific proteins Beta241, Beta201, Beta286, and Beta371 genes, complete coding regions) position: , mismatch: 3, identity: 0.903

gatatcggcagcacctgacaaggtgaatccg	CRISPR spacer
ggtgtcggcagcccctgacaaggtgaatccg	Protospacer
*.*.******** ******************

2. spacer 1.2|27403|30|NZ_CP011095|PILER-CR matches to NZ_CP011543 (Corynebacterium mustelae strain DSM 45274 plasmid pCmus45274, complete sequence) position: , mismatch: 5, identity: 0.833

cgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
cgcatccgtacgattgagacgtgttaacgc	Protospacer
****** **.************** *. **

3. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP011543 (Corynebacterium mustelae strain DSM 45274 plasmid pCmus45274, complete sequence) position: , mismatch: 5, identity: 0.844

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatccgtacgattgagacgtgttaacgc	Protospacer
******** **.************** *. **

4. spacer 2.18|1893006|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP016462 (Blastomonas sp. RAC04 plasmid pBSY18_1, complete sequence) position: , mismatch: 5, identity: 0.844

agcggccccctcaccctgcaaggcggtggagc-	CRISPR spacer
atcggcgcgctcaccctgcaaggcgg-ggcgcg	Protospacer
* **** * ***************** ** **

5. spacer 1.3|27464|30|NZ_CP011095|PILER-CR matches to NZ_CP054842 (Acidovorax sp. 16-35-5 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

ttcaatttccacgcggtcggt---gaagatgcc	CRISPR spacer
ttcaatgtccacgcggtcggtttccaggat---	Protospacer
****** **************    *.***

6. spacer 1.3|27464|30|NZ_CP011095|PILER-CR matches to NZ_CP025613 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

ttcaatttc----cacgcggtcggtgaagatgcc	CRISPR spacer
----atccccgaacacccggtcggtgaagatgcc	Protospacer
    **..*    *** *****************

7. spacer 2.11|1892578|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 7, identity: 0.781

gcctacagcttccacggctgcgt----tagccgtgt	CRISPR spacer
gccaacagcttccacggccgcgtccagtagct----	Protospacer
*** **************.****    ****.

8. spacer 2.13|1892700|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP032928 (Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence) position: , mismatch: 7, identity: 0.781

gaggttgtcggtgtcgcggcgtcggttatcgc	CRISPR spacer
aaggttggcggtgtcacggcgtcggacggcgc	Protospacer
.****** *******.********* .. ***

9. spacer 1.3|27464|30|NZ_CP011095|PILER-CR matches to NZ_CP032676 (Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence) position: , mismatch: 8, identity: 0.733

ttcaatttccacgcggtcggtgaagatgcc	CRISPR spacer
tggggcggccacgcggtcggtgaagctgcc	Protospacer
*  ...  ***************** ****

10. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

11. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

12. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

13. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

14. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

15. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

16. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

17. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

18. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

19. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

20. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

21. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

22. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

23. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_010998 (Rhizobium etli CIAT 652 plasmid pA, complete sequence) position: , mismatch: 8, identity: 0.75

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcaaccaagc	Protospacer
**************.***** **..   .***

24. spacer 2.1|1891967|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_AP014708 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_4p, complete sequence) position: , mismatch: 8, identity: 0.75

tatggacgtgccaatcaacctcaa-accaattc	CRISPR spacer
tatcgacgtgccgatcaacctcaacgtcgagg-	Protospacer
*** ********.*********** ..*.*

25. spacer 2.12|1892639|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP049734 (Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcaggggcgactttagtgacgcggagtc	CRISPR spacer
gacctcaggggcgacgtaagtgacgcctctcc	Protospacer
 ************** * ********    .*

26. spacer 2.12|1892639|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP016288 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed7, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcaggggcgactttagtgacgcggagtc	CRISPR spacer
gacctcaggggcgacgtaagtgacgcctctcc	Protospacer
 ************** * ********    .*

27. spacer 2.12|1892639|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcaggggcgactttagtgacgcggagtc	CRISPR spacer
gacctcaggggcgacgtaagtgacgcctctcc	Protospacer
 ************** * ********    .*

28. spacer 2.12|1892639|32|NZ_CP011095|CRISPRCasFinder,CRT matches to CP049734 (Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcaggggcgactttagtgacgcggagtc	CRISPR spacer
gacctcaggggcgacgtaagtgacgcctctcc	Protospacer
 ************** * ********    .*

29. spacer 2.12|1892639|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP030762 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcaggggcgactttagtgacgcggagtc	CRISPR spacer
gacctcaggggcgacgtgagtgacgcctctcc	Protospacer
 ************** * ********    .*

30. spacer 2.12|1892639|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP050089 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b2, complete sequence) position: , mismatch: 8, identity: 0.75

tacctcaggggcgactttagtgacgcggagtc	CRISPR spacer
gacctcaggggcgacgtgagtgacgcctctcc	Protospacer
 ************** * ********    .*

31. spacer 2.13|1892700|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP007515 (Rubrobacter radiotolerans strain RSPS-4 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

gaggttgtcggtgtcgcggcgtcggttatcgc	CRISPR spacer
gtctttgtgggtgtcgcggcgtcggctacctt	Protospacer
*   **** ****************.**.* .

32. spacer 2.18|1893006|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP049359 (Deinococcus wulumuqiensis R12 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

agcggccccctcaccctgcaaggcggtggagc	CRISPR spacer
cccggcccccagaccctgcaaggcgcgtgcgc	Protospacer
  ********  *************   * **

33. spacer 2.31|1892699|34|NZ_CP011095|PILER-CR matches to NZ_CP032928 (Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence) position: , mismatch: 8, identity: 0.765

cgaggttgtcggtgtcgcggcgtcggttatcgcc	CRISPR spacer
caaggttggcggtgtcacggcgtcggacggcgct	Protospacer
*.****** *******.********* .. ***.

34. spacer 1.5|27401|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 9, identity: 0.719

gtcgcatcggtgcgattgagacgtgtgagagc	CRISPR spacer
gtcgcatcggtgcggttgagccgcagccaggc	Protospacer
**************.***** **..   ..**

35. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_KP975076 (Pseudomonas aeruginosa strain MRSN17623 plasmid pMRVIM0713, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

36. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP010958 (Sphingobium sp. YBL2 plasmid 4pYBL2-4, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

37. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP015373 (Pandoraea pnomenusa strain MCB032 plasmid unnamed 2, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

38. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to MN336501 (Pseudomonas aeruginosa strain 164130 plasmid p4130-KPC, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

39. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

40. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

41. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP010801 (Ralstonia mannitolilytica strain SN82F48 plasmid pRMAN01, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

42. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_017908 (Mycobacterium abscessus subsp. bolletii F1725 plasmid BRA100, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

43. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_MN433457 (Pseudomonas aeruginosa strain PAB546 plasmid pNK546-KPC, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

44. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP046330 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

45. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP046332 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed2) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

46. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP026545 (Cupriavidus metallidurans strain Ni-2 plasmid unnamed1) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

47. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_KU237244 (Sphingomonas sp. SH plasmid pSH, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

48. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP026974 (Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

49. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to KM659090 (Achromobacter sp. LM16 plasmid pLM16A1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

50. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JX469831 (Uncultured bacterium plasmid pKSP212, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

51. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to MF344569 (Pseudomonas aeruginosa plasmid p12939-PER, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

52. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JN106172 (Uncultured bacterium plasmid pAKD29, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

53. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JN106173 (Uncultured bacterium plasmid pAKD31, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

54. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JN106174 (Uncultured bacterium plasmid pAKD33, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

55. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

56. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

57. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

58. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_002698 (Shigella flexneri 5a virulence plasmid pWR501, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

59. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JN106165 (Uncultured bacterium plasmid pAKD14, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

60. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JN106166 (Uncultured bacterium plasmid pAKD15, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

61. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JN106168 (Uncultured bacterium plasmid pAKD17, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

62. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JN106169 (Uncultured bacterium plasmid pAKD18, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

63. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP026230 (Aeromonas sp. ASNIH1 plasmid pKPC-038c, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

64. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to MN583270 (Pseudomonas aeruginosa strain NK546 plasmid pNK546b, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

65. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_016978 (Comamonas testosteroni plasmid pI2, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

66. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP017451 (Klebsiella sp. LTGPAF-6F plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

67. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP027173 (Pseudomonas aeruginosa strain AR_0353 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

68. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to KF743817 (Proteus mirabilis plasmid R772, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

69. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to KF743818 (Bordetella bronchiseptica plasmid R906, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

70. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_006525 (Cupriavidus metallidurans CH34 plasmid pMOL28, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

71. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_019906 (Pseudomonas putida HB3267 plasmid pPC9, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

72. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to JX194160 (Uncultured bacterium plasmid pM02_c6 clone c6, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

73. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_009739 (Pseudomonas aeruginosa plasmid pMATVIM-7, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

74. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_006466 (Cupriavidus metallidurans CH34 plasmid pMOL30, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

75. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_021077 (Comamonas sp. 7D-2 plasmid pBHB, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

76. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP043439 (Cupriavidus campinensis strain MJ1 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

77. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_LT882698 (Klebsiella pneumoniae strain Klebsiella pneumoniae KLPN57 isolate KLPN57 plasmid I, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

78. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_MK851048 (Morganella morganii strain MM1L5 plasmid pMM1L5, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

79. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_MK851047 (Actinobacillus pleuropneumoniae strain APP1L5 plasmid pAPP1L5, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

80. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP033834 (Pseudomonas aeruginosa strain FDAARGOS_570 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

81. spacer 2.2|1892028|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP048383 (Citrobacter freundii strain 62 plasmid p6_A, complete sequence) position: , mismatch: 9, identity: 0.719

cttccatccatgctctgcccgtgcgcacgagg	CRISPR spacer
accacatccatgcccagcccgtgcgcaagctg	Protospacer
 .. *********.* *********** *  *

82. spacer 2.8|1892395|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NZ_CP009295 (Novosphingobium pentaromativorans US6-1 plasmid pLA5, complete sequence) position: , mismatch: 9, identity: 0.719

tgccccgctaggggcgtgggtggctgggtgct	CRISPR spacer
ctcgccaccaggggcgtgggtggctggccgga	Protospacer
. * **.*.****************** .*

83. spacer 2.8|1892395|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 9, identity: 0.719

tgccccgctaggggcgtgggtggctgggtgct	CRISPR spacer
ctcgccaccaggggcgtgggtggctggccgga	Protospacer
. * **.*.****************** .*

84. spacer 2.10|1892517|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 9, identity: 0.719

aaaggcaatgcacggataccccgcgctccggt	CRISPR spacer
atcggcactgcgcggataccccgcgcctgcgg	Protospacer
*  **** ***.**************..  *

85. spacer 2.31|1892699|34|NZ_CP011095|PILER-CR matches to NZ_CP007515 (Rubrobacter radiotolerans strain RSPS-4 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.735

cgaggttgtcggtgtcgcggcgtcggttatcgcc	CRISPR spacer
ggtctttgtgggtgtcgcggcgtcggctaccttc	Protospacer
 *   **** ****************.**.* .*

86. spacer 2.18|1893006|32|NZ_CP011095|CRISPRCasFinder,CRT matches to NC_041927 (Sphingobium phage Lacusarx, complete genome) position: , mismatch: 10, identity: 0.688

agcggccccctcaccctgcaaggcggtggagc	CRISPR spacer
ccacttcttctcaccctgcgaggcggtgaagc	Protospacer
     .*..**********.********.***

87. spacer 2.30|1892638|34|NZ_CP011095|PILER-CR matches to NZ_CP049734 (Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ctacctcaggggcgactttagtgacgcggagtcc	CRISPR spacer
ggacctcaggggcgacgtaagtgacgcctctccg	Protospacer
  ************** * ********    .*

88. spacer 2.30|1892638|34|NZ_CP011095|PILER-CR matches to CP049734 (Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence) position: , mismatch: 10, identity: 0.706

ctacctcaggggcgactttagtgacgcggagtcc	CRISPR spacer
ggacctcaggggcgacgtaagtgacgcctctccg	Protospacer
  ************** * ********    .*

89. spacer 2.30|1892638|34|NZ_CP011095|PILER-CR matches to NZ_CP030762 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

ctacctcaggggcgactttagtgacgcggagtcc	CRISPR spacer
ggacctcaggggcgacgtgagtgacgcctctccg	Protospacer
  ************** * ********    .*

90. spacer 2.30|1892638|34|NZ_CP011095|PILER-CR matches to NZ_CP016288 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed7, complete sequence) position: , mismatch: 10, identity: 0.706

ctacctcaggggcgactttagtgacgcggagtcc	CRISPR spacer
ggacctcaggggcgacgtaagtgacgcctctccg	Protospacer
  ************** * ********    .*

91. spacer 2.30|1892638|34|NZ_CP011095|PILER-CR matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 10, identity: 0.706

ctacctcaggggcgactttagtgacgcggagtcc	CRISPR spacer
ggacctcaggggcgacgtaagtgacgcctctccg	Protospacer
  ************** * ********    .*

92. spacer 2.30|1892638|34|NZ_CP011095|PILER-CR matches to NZ_CP050089 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b2, complete sequence) position: , mismatch: 10, identity: 0.706

ctacctcaggggcgactttagtgacgcggagtcc	CRISPR spacer
ggacctcaggggcgacgtgagtgacgcctctccg	Protospacer
  ************** * ********    .*

93. spacer 2.19|1891966|34|NZ_CP011095|PILER-CR matches to NZ_AP014708 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_4p, complete sequence) position: , mismatch: 11, identity: 0.676

atatggacgtgccaatcaacctcaaaccaattcc--------	CRISPR spacer
gtatcgacgtgccgatcaacctcaa--------cgtcgaggg	Protospacer
.*** ********.***********        *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1814339 : 1886241

Tupanvirus(27.27%)

protease,bacteriocin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038620741.1\|1814339_1815626_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	3.0e-132	55.6
WP_046096204.1\|1815788_1818590_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	1.3e-84	33.4
WP_013912108.1\|1818666_1819296_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	1.4e-37	43.5
WP_013912109.1\|1819311_1819911_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	1.3e-42	48.3
WP_046096205.1\|1820262_1821615_-	trigger factor	NA	NA	NA	NA
WP_023636123.1\|1822489_1822732_+	hypothetical protein	A0A1W6JRB8	Corynebacterium_phage	3.9e-09	48.4
WP_023636124.1\|1822866_1823670_+	hypothetical protein	NA	NA	NA	NA
WP_046096206.1\|1823756_1824767_-	pirin family protein	NA	NA	NA	NA
WP_046096645.1\|1824881_1825355_-	ribose-5-phosphate isomerase	NA	NA	NA	NA
WP_046096207.1\|1825546_1826167_-	DSBA oxidoreductase	NA	NA	NA	NA
WP_046096208.1\|1826465_1829081_+	aminopeptidase N	A0A2K9L1R3	Tupanvirus	2.2e-41	32.3
WP_038622769.1\|1829498_1830173_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_046096209.1\|1830198_1830591_+	globin	NA	NA	NA	NA
WP_046096210.1\|1830602_1831499_+	DMT family transporter	NA	NA	NA	NA
WP_046096211.1\|1831509_1832118_-	hypothetical protein	NA	NA	NA	NA
WP_046096212.1\|1832123_1832552_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_014526132.1\|1832753_1834424_-	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	2.3e-47	27.6
WP_046096213.1\|1834592_1835159_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_046096214.1\|1835693_1837418_+	hypothetical protein	NA	NA	NA	NA
WP_046096215.1\|1837414_1838965_+	YcaO-like family protein	NA	NA	NA	NA
WP_046096216.1\|1839000_1840485_+	nitroreductase	NA	NA	NA	NA
WP_046096217.1\|1840481_1843082_+	lantibiotic dehydratase	NA	NA	NA	NA
WP_046096218.1\|1843081_1844095_+	hypothetical protein	NA	NA	NA	NA
WP_046096219.1\|1844091_1845069_+	hypothetical protein	NA	NA	NA	NA
WP_101507658.1\|1845107_1845284_+\|bacteriocin	thiazolylpeptide-type bacteriocin	NA	NA	NA	NA
WP_046096646.1\|1845358_1846810_+	hypothetical protein	NA	NA	NA	NA
WP_046096220.1\|1846843_1847602_-	permease	NA	NA	NA	NA
WP_046096221.1\|1847598_1848522_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.1e-19	26.1
WP_046096222.1\|1848659_1850705_-	bifunctional copper resistance protein CopD/cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_046096223.1\|1851305_1853591_+	carbon starvation protein A	NA	NA	NA	NA
WP_013912136.1\|1853610_1853811_+	YbdD/YjiX family protein	NA	NA	NA	NA
WP_046096224.1\|1854362_1855052_+	hypothetical protein	NA	NA	NA	NA
WP_046096225.1\|1855145_1856987_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	3.3e-31	33.2
WP_046096226.1\|1857260_1858256_+	oxidoreductase	NA	NA	NA	NA
WP_080940725.1\|1858394_1859198_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_155392580.1\|1859263_1859923_+	oligoribonuclease	M4M9I5	Vibrio_phage	3.8e-22	35.1
WP_046096647.1\|1860102_1860930_+	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_080940726.1\|1860992_1862180_-	L,D-transpeptidase	NA	NA	NA	NA
WP_046096230.1\|1862853_1863849_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_046096231.1\|1864059_1864614_+	isochorismatase family protein	A0A2K9L2K0	Tupanvirus	1.3e-15	31.7
WP_046096232.1\|1864623_1864968_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_013912165.1\|1865081_1865357_-	DUF3618 domain-containing protein	NA	NA	NA	NA
WP_046096233.1\|1865445_1865925_+	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_023636151.1\|1865965_1866619_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_046096234.1\|1866622_1867018_-	holo-ACP synthase	NA	NA	NA	NA
WP_046096235.1\|1867152_1876251_-	type I polyketide synthase	NA	NA	NA	NA
WP_046096236.1\|1876472_1876721_-	hypothetical protein	NA	NA	NA	NA
WP_046096648.1\|1877098_1878055_+	two-component sensor histidine kinase	NA	NA	NA	NA
WP_046096237.1\|1878051_1878678_+	response regulator transcription factor	NA	NA	NA	NA
WP_046096238.1\|1878724_1879768_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_046096240.1\|1880247_1880694_+	hypothetical protein	NA	NA	NA	NA
WP_023636159.1\|1880770_1881130_+	DUF3817 domain-containing protein	NA	NA	NA	NA
WP_046096241.1\|1881199_1881823_-	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	NA	NA	NA	NA
WP_046096242.1\|1881819_1882554_-	ribonuclease PH	NA	NA	NA	NA
WP_046096243.1\|1882592_1883360_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_023636163.1\|1883432_1884326_-	glutamate racemase	NA	NA	NA	NA
WP_046096244.1\|1884392_1885211_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_038620771.1\|1885296_1885833_-	DUF2017 domain-containing protein	NA	NA	NA	NA
WP_032802901.1\|1885941_1886241_-\|protease	ATP-dependent Clp protease adapter ClpS	NA	NA	NA	NA

DBSCAN-SWA_2

2026750 : 2035214

Pandoravirus(33.33%)

holin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046096311.1\|2026750_2028499_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	5.8e-62	32.1
WP_046096312.1\|2028476_2029145_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
WP_046096313.1\|2029152_2029539_-	hypothetical protein	NA	NA	NA	NA
WP_029974149.1\|2029535_2030051_-	hypothetical protein	NA	NA	NA	NA
WP_046096314.1\|2030061_2030508_-	DUF3180 domain-containing protein	NA	NA	NA	NA
WP_046096315.1\|2030504_2030960_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	S4VNV0	Pandoravirus	6.7e-10	35.0
WP_046096316.1\|2030961_2031303_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_046096317.1\|2031289_2032072_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	1.1e-20	32.2
WP_013912364.1\|2032073_2032637_-	GTP cyclohydrolase I FolE	A0A1W7AF02	Streptococcus_virus	8.2e-50	58.2
WP_155392590.1\|2032629_2034588_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	2.0e-111	50.7
WP_014836795.1\|2034632_2035214_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	3.9e-15	31.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011095

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection