CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014222	Janthinobacterium sp. B9-8, complete genome	2 crisprs	csa3,DEDDh,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DinG,WYL,RT	3	16	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014222_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014222_1

171777-173574

TypeI-E

I-E

Consensus_repeat	Method
GCGTTCCCCGCACCAGCGGGGCTGAACCG	PILER-CR
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CRISPRCasFinder
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CRT

29 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP014222_1

>merge|NZ_CP014222|1|171777-173574|PILER-CR,CRISPRCasFinder,CRT
GCGTTCCCCGCACCAGCGGGGCTGAACCGACGGTGATTTTTTGGTATTAAACGCCAATAATGCGTTCCCCGCACCAGCGGGGCTGAACCGGCCATCCACGCTAGCAAGTCGTGACTGCTTAAGCGTTCCCCGCACCAGCGGGGCTGAACCGGCTGGAAACAAATTGTCATCGCTGGCCCCGGCGCGTTCCCCGCACCAGCGGGGCTGAACCGCTGGCATCAACGAATCTGGCACCATTGAAGCTGCGTTCCCCGCACCAGCGGGGCTGAACCGACTCGCTAGTTATGCGGCCTGTTGTTGAGGATGCGTTCCCCGCACCAGCGGGGCTGAACCGCCATGTGTGATCGTATTTTTCCATTTTTAACAGCGTTCCCCGCACCAGCGGGGCTGAACCGCGACAACAAGAACTACAACATCCGCGCCCTAAGCGTTCCCCGCACCAGCGGGGCTGAACCGCCTTTCAATTGGTGGTACACATTCGCCAACTGGCGTTCCCCGCACCAGCGGGGCTGAACCGTTCTGCCCACGCGAGGCAAGCATTGCAGCAGCGCGTTCCCCGCACCAGCGGGGCTGAACCGACGCGATGTTGATGCGGTTTGCCCAGTCCAAAGCGTTCCCCGCACCAGCGGGGCTGAACCGGTAAATACACACCTGATTTAACAATATTTTCGGCGTTCCCCGCACCAGCGGGGCTGAACCGCGTAATCGGCATAATCAACAACCAGATTAATTGCGTTCCCCGCACCAGCGGGGCTGAACCGCCAAAACCCCAGATAGAATCAGGGTCAACAACGCGTTCCCCGCACCAGCGGGGCTGAACCGTAAAAATATGGCAACATACCCATAAATAAACAGCGTTCCCCGCACCAGCGGGGCTGAACCGTATCAACTTCTAAAACACCCAAAACTTCAATTGCGTTCCCCGCACCAGCGGGGCTGAACCGCCAGCTTCTGAAAATGCGTCTGGCCCAGGTGAGCGTTCCCCGCACCAGCGGGGCTGAACCGGCGTCGGATTTTCTACCCAGTGCAAAAACTCAGCGTTCCCCGCACCAGCGGGGCTGAACCTTGCCTGAGGCGTCGAGCGGCGTCGGCCTGACCGCGTTCCCCGCACCAGCGGGGCTGAACCGGCCCGCCCCAGCCAGAGCACCGCACGGCCAACGCGTTCCCCGCACCAGCGGGGCTGAACCGGTTGTTTCTAAATCAACCGTGGCTGAAGTAGAGCGTTCCCCGCACCAGCGGGGCTGAACCGCGAGTGTCAACGAAGCTAGTGTCAACGAAGCGGCGTTCCCCGCACCAGCGGGGCTGAACCGATATCATCGTTGTGGAATTAAATGGCGGCATAGCGTTCCCCGCACCAGCGGGGCTGAACCGGCCCAATTTGAATGTATGGGCAGGCTATCATCGCGTTCCCCGCATCAGCGGGGCTGAACCGCGCCCAGCCCAAGGTGGCGCACTCATACGCCAGCGTTCCCCGCACCAGCGGGGCTGAACCGCAGGTAATTTGGCTATGTCAGGGGAGGGGATGGCGTTCCCCGCACCAGCGGGGCTGAACCGTCAGGCGAGCGCCTTAAAGGAGTTTCGGCTTGGCGTTCCCCGCACCAGCGGGGCTGAACCGTCGTCAGGTAGTGCGCTTGGTAAATCAATCACGCGTTCCCCGCACCAGCGGGGCTGAACCGTCGTCAGGTAGTGCGCTTGGTAAATCAATCACGCGTTCCCCGCACCAGCGGGGCTGAACCGGTCGGCAGCTATATCGTGCCGATCGATATCATGCGTTCCCCGCACCAGCGGGGCGGAGTCA

>NZ_CP014222|1|1|171777-173513|PILER-CR
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACGGTGATTTTTTGGTATTAAACGCCAATAAT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCATCCACGCTAGCAAGTCGTGACTGCTTAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCTGGAAACAAATTGTCATCGCTGGCCCCGGC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CTGGCATCAACGAATCTGGCACCATTGAAGCT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACTCGCTAGTTATGCGGCCTGTTGTTGAGGAT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCATGTGTGATCGTATTTTTCCATTTTTAACA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGACAACAAGAACTACAACATCCGCGCCCTAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCTTTCAATTGGTGGTACACATTCGCCAACTG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TTCTGCCCACGCGAGGCAAGCATTGCAGCAGC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACGCGATGTTGATGCGGTTTGCCCAGTCCAAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GTAAATACACACCTGATTTAACAATATTTTCG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGTAATCGGCATAATCAACAACCAGATTAATT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCAAAACCCCAGATAGAATCAGGGTCAACAAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TAAAAATATGGCAACATACCCATAAATAAACA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TATCAACTTCTAAAACACCCAAAACTTCAATT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCAGCTTCTGAAAATGCGTCTGGCCCAGGTGA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCGTCGGATTTTCTACCCAGTGCAAAAACTCA
GCGTTCCCCGCACCAGCGGGGCTGAACCT	TGCCTGAGGCGTCGAGCGGCGTCGGCCTGACC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCCGCCCCAGCCAGAGCACCGCACGGCCAAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GTTGTTTCTAAATCAACCGTGGCTGAAGTAGA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGAGTGTCAACGAAGCTAGTGTCAACGAAGCG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ATATCATCGTTGTGGAATTAAATGGCGGCATA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCCAATTTGAATGTATGGGCAGGCTATCATC
GCGTTCCCCGCATCAGCGGGGCTGAACCG	CGCCCAGCCCAAGGTGGCGCACTCATACGCCA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CAGGTAATTTGGCTATGTCAGGGGAGGGGATG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCAGGCGAGCGCCTTAAAGGAGTTTCGGCTTG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCGTCAGGTAGTGCGCTTGGTAAATCAATCAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCGTCAGGTAGTGCGCTTGGTAAATCAATCAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG

>NZ_CP014222|1|1|171777-173574|CRISPRCasFinder
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACGGTGATTTTTTGGTATTAAACGCCAATAAT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCATCCACGCTAGCAAGTCGTGACTGCTTAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCTGGAAACAAATTGTCATCGCTGGCCCCGGC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CTGGCATCAACGAATCTGGCACCATTGAAGCT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACTCGCTAGTTATGCGGCCTGTTGTTGAGGAT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCATGTGTGATCGTATTTTTCCATTTTTAACA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGACAACAAGAACTACAACATCCGCGCCCTAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCTTTCAATTGGTGGTACACATTCGCCAACTG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TTCTGCCCACGCGAGGCAAGCATTGCAGCAGC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACGCGATGTTGATGCGGTTTGCCCAGTCCAAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GTAAATACACACCTGATTTAACAATATTTTCG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGTAATCGGCATAATCAACAACCAGATTAATT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCAAAACCCCAGATAGAATCAGGGTCAACAAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TAAAAATATGGCAACATACCCATAAATAAACA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TATCAACTTCTAAAACACCCAAAACTTCAATT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCAGCTTCTGAAAATGCGTCTGGCCCAGGTGA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCGTCGGATTTTCTACCCAGTGCAAAAACTCA
GCGTTCCCCGCACCAGCGGGGCTGAACCT	TGCCTGAGGCGTCGAGCGGCGTCGGCCTGACC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCCGCCCCAGCCAGAGCACCGCACGGCCAAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GTTGTTTCTAAATCAACCGTGGCTGAAGTAGA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGAGTGTCAACGAAGCTAGTGTCAACGAAGCG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ATATCATCGTTGTGGAATTAAATGGCGGCATA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCCAATTTGAATGTATGGGCAGGCTATCATC
GCGTTCCCCGCATCAGCGGGGCTGAACCG	CGCCCAGCCCAAGGTGGCGCACTCATACGCCA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CAGGTAATTTGGCTATGTCAGGGGAGGGGATG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCAGGCGAGCGCCTTAAAGGAGTTTCGGCTTG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCGTCAGGTAGTGCGCTTGGTAAATCAATCAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCGTCAGGTAGTGCGCTTGGTAAATCAATCAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GTCGGCAGCTATATCGTGCCGATCGATATCAT
GCGTTCCCCGCACCAGCGGGGCGGAGTCA

>NZ_CP014222|1|1|171777-173574|CRT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACGGTGATTTTTTGGTATTAAACGCCAATAAT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCATCCACGCTAGCAAGTCGTGACTGCTTAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCTGGAAACAAATTGTCATCGCTGGCCCCGGC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CTGGCATCAACGAATCTGGCACCATTGAAGCT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACTCGCTAGTTATGCGGCCTGTTGTTGAGGAT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCATGTGTGATCGTATTTTTCCATTTTTAACA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGACAACAAGAACTACAACATCCGCGCCCTAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCTTTCAATTGGTGGTACACATTCGCCAACTG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TTCTGCCCACGCGAGGCAAGCATTGCAGCAGC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ACGCGATGTTGATGCGGTTTGCCCAGTCCAAA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GTAAATACACACCTGATTTAACAATATTTTCG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGTAATCGGCATAATCAACAACCAGATTAATT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCAAAACCCCAGATAGAATCAGGGTCAACAAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TAAAAATATGGCAACATACCCATAAATAAACA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TATCAACTTCTAAAACACCCAAAACTTCAATT
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CCAGCTTCTGAAAATGCGTCTGGCCCAGGTGA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCGTCGGATTTTCTACCCAGTGCAAAAACTCA
GCGTTCCCCGCACCAGCGGGGCTGAACCT	TGCCTGAGGCGTCGAGCGGCGTCGGCCTGACC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCCGCCCCAGCCAGAGCACCGCACGGCCAAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GTTGTTTCTAAATCAACCGTGGCTGAAGTAGA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CGAGTGTCAACGAAGCTAGTGTCAACGAAGCG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	ATATCATCGTTGTGGAATTAAATGGCGGCATA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GCCCAATTTGAATGTATGGGCAGGCTATCATC
GCGTTCCCCGCATCAGCGGGGCTGAACCG	CGCCCAGCCCAAGGTGGCGCACTCATACGCCA
GCGTTCCCCGCACCAGCGGGGCTGAACCG	CAGGTAATTTGGCTATGTCAGGGGAGGGGATG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCAGGCGAGCGCCTTAAAGGAGTTTCGGCTTG
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCGTCAGGTAGTGCGCTTGGTAAATCAATCAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	TCGTCAGGTAGTGCGCTTGGTAAATCAATCAC
GCGTTCCCCGCACCAGCGGGGCTGAACCG	GTCGGCAGCTATATCGTGCCGATCGATATCAT
GCGTTCCCCGCACCAGCGGGGCGGAGTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014222.1\|WP_046350966.1\|183188_183716_-\|inorganic-diphosphatase	unknown	unknown	gnl\|CDD\|179262
NZ_CP014222.1\|WP_046350954.1\|163093_165814_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP014222.1\|WP_046350953.1\|158883_162849_+\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|274093
NZ_CP014222.1\|WP_046350964.1\|180324_181443_+\|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176260
NZ_CP014222.1\|WP_046350957.1\|167992_169027_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP014222.1\|WP_046350959.1\|171376_171670_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP014222.1\|WP_046350952.1\|158071_158737_+\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|132881
NZ_CP014222.1\|WP_046351118.1\|170484_171396_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP014222.1\|WP_046350958.1\|169031_169769_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP014222.1\|WP_046350955.1\|165853_167431_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|187860
NZ_CP014222.1\|WP_082752878.1\|167411_167978_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP014222.1\|WP_052746476.1\|169765_170479_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09727_cas6e_CAS-I-E	gnl\|CDD\|215025
NZ_CP014222.1\|WP_046350963.1\|178843_179713_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176159
NZ_CP014222.1\|WP_052746479.1\|175133_176408_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226582
NZ_CP014222.1\|WP_156455088.1\|176575_177379_+\|TonB-family-protein	unknown	unknown	gnl\|CDD\|223880
NZ_CP014222.1\|WP_156455243.1\|178043_178397_+\|translation-initiation-factor-Sui1	unknown	unknown	gnl\|CDD\|168689
NZ_CP014222.1\|WP_046350967.1\|183989_186671_+\|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223972
NZ_CP014222.1\|WP_156455089.1\|181844_182690_+\|S-formylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|178061
NZ_CP014222.1\|WP_052746478.1\|174135_174768_-\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl\|CDD\|377877
NZ_CP014222.1\|WP_082752527.1\|173711_174071_+\|DUF1294-domain-containing-protein	unknown	unknown	gnl\|CDD\|377743

Protein	Function_ID	Function_description	E-value
NZ_CP014222.1\|WP_046350966.1\|183188_183716_-\|inorganic-diphosphatase	gnl\|CDD\|179262	PRK01250, PRK01250, inorganic diphosphatase.	1.08732e-113
NZ_CP014222.1\|WP_046350954.1\|163093_165814_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.66366e-131
NZ_CP014222.1\|WP_046350953.1\|158883_162849_+\|non-ribosomal-peptide-synthetase	gnl\|CDD\|274093	TIGR02353, NON-RIBOSOMAL_PEPTIDE_SYNTHETASE, non-ribosomal peptide synthetase terminal domain of unknown function. This domain is found exclusively in non-ribosomal peptide synthetases and always as the final domain in the polypeptide. This domain is roughly 700 amino acids in size and is found in polypeptides roughly twice that size.	0
NZ_CP014222.1\|WP_046350964.1\|180324_181443_+\|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase	gnl\|CDD\|176260	cd08300, alcohol_DH_class_III, class III alcohol dehydrogenases. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	0
NZ_CP014222.1\|WP_046350957.1\|167992_169027_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	8.75665e-113
NZ_CP014222.1\|WP_046350959.1\|171376_171670_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.97556e-59
NZ_CP014222.1\|WP_046350952.1\|158071_158737_+\|DNA-alkylation-repair-protein	gnl\|CDD\|132881	cd07064, AlkD_like_1, A new structural DNA glycosylase containing HEAT-like repeats. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity. The known structures for members of this family, AlkC and AlkD from Bacillus cereus, are distant homologues and are composed of six variant HEAT (Huntington/Elongation/ A subunit/Target of rapamycin) repeats. HEAT motifs are ~45-amino acid sequences that form antiparallel alpha-helices, which are packed by a conserved hyrophobic interface and are tandemly repeated to form superhelical alpha-structures. AlkD and AlkC are specific for removal of 3-methyladenine (3mA) and 7-methylguanine (7mG) from the DNA by base excision repair. Homologues of AlkC and AlkD were also identified in other organisms.	6.42277e-86
NZ_CP014222.1\|WP_046351118.1\|170484_171396_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	5.56919e-150
NZ_CP014222.1\|WP_046350958.1\|169031_169769_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.173e-43
NZ_CP014222.1\|WP_046350955.1\|165853_167431_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	5.8278e-109
NZ_CP014222.1\|WP_082752878.1\|167411_167978_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	2.94745e-28
NZ_CP014222.1\|WP_052746476.1\|169765_170479_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|215025	smart01101, CRISPR_assoc, This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	9.44228e-46
NZ_CP014222.1\|WP_046350963.1\|178843_179713_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176159	cd08470, PBP2_CrgA_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding domain. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 1. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.76607e-88
NZ_CP014222.1\|WP_052746479.1\|175133_176408_-\|hypothetical-protein	gnl\|CDD\|226582	COG4097, COG4097, Predicted ferric reductase [Inorganic ion transport and metabolism].	8.82806e-93
NZ_CP014222.1\|WP_156455088.1\|176575_177379_+\|TonB-family-protein	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	2.32203e-11
NZ_CP014222.1\|WP_156455243.1\|178043_178397_+\|translation-initiation-factor-Sui1	gnl\|CDD\|168689	PRK06824, PRK06824, translation initiation factor Sui1; Validated.	3.74857e-60
NZ_CP014222.1\|WP_046350967.1\|183989_186671_+\|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	gnl\|CDD\|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	1.66802e-144
NZ_CP014222.1\|WP_156455089.1\|181844_182690_+\|S-formylglutathione-hydrolase	gnl\|CDD\|178061	PLN02442, PLN02442, S-formylglutathione hydrolase.	9.41125e-136
NZ_CP014222.1\|WP_052746478.1\|174135_174768_-\|PEP-CTERM-sorting-domain-containing-protein	gnl\|CDD\|377877	pfam07589, VPEP, PEP-CTERM motif. This motif has been identified in a wide range of bacteria at their C-terminus. It has been suggested that this is a protein sorting signal. Based on phylogenetic profiling it has been suggested that the EpsH family of proteins mediate this function.	2.0376e-06
NZ_CP014222.1\|WP_082752527.1\|173711_174071_+\|DUF1294-domain-containing-protein	gnl\|CDD\|377743	pfam06961, DUF1294, Protein of unknown function (DUF1294). This family includes a number of hypothetical bacterial and archaeal proteins of unknown function.	8.33612e-23

>NZ_CP014222.1|WP_046350959.1|171376_171670_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MLVIVLENAPPRLRGRMAIWLLEIRAGVYVGNYSKKVRESIWSQVAAGIEDGNAVMAWRTNNEAGFDFETLGKNRRIPVELDGAKLVSFLPVEQKES
>NZ_CP014222.1|WP_046351118.1|170484_171396_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MLPKLKPIPIKERLSVLFIEKCQLDVIDGAFVVVDSTGVRKHIPIGGVVCLMLEPGVRVSHAACKLAAMVGTLLVWVGEAGVRLYSAGQPGGARADRLLYQAKLALDDDARLKVVREMYRRRFGEEPPQRRSVEQLRGIEGARVRATYQLLAKQYGVQWRSRNYDQKDWDAADIPNRCLSAATSCLYGVTEAAVLAAGYAPAIGFIHTGKPLSFVYDIADVYKFETVVPVAFSVASKPCANPEREVRIRLRDVFRQSKLLERIIPDIEEILAAGELEKPEAHEEAVLPAIPNEESMGDAGHRA
>NZ_CP014222.1|WP_052746476.1|169765_170479_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MSYFSRISIGHKALADGELSEAIGAGDAYRDHQLMWKLFPSEANTQRDFVFRAEVREQQATTRSLLYYIVSQREPVAWHSEVKVQSKPYAPLLEEGEWVHFDLRANPTVSVAAQKGQRGKRHDVLMHAKHLHKEQSVAQSAEAVEKAALAWLANRAANWGLQIDMESVQIDAYRQYKLHTKGREIQFSTVDYRGQAKVSNSERLSHALLSGISNKSQAGLGHSQGFGCGLLLVKRML
>NZ_CP014222.1|WP_046350958.1|169031_169769_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFRLYGAMASFGEIAVGELRHSAVYPSRSALLGLLAAALGIPRSDEAGQQALINGYRFGVKLIASGTPLRDYHTVQSPAISKKITYRTRKQEMADKDKLSTILTSREYRTDGLYMVAVDALNDAPFSLQQLAGALDKPIFQLYLGRKSCPLALPLAAIVAEFESLKMALDSRDQQALLPEMLAVSRALRLDRSPRYFWEQGMDSGMDATLTQTRSDQPLSRARWQFAPRQELVFMSGVGS
>NZ_CP014222.1|WP_046350957.1|167992_169027_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MNRFIQLHTLISYPPANLNRDDQGRPKTAKMGGVERLRVSSQSLKRAWRTSDVFNEQLAEKIGVRTKLLGQEHVYKPMIAAGISEKNASDWASKIAAVYGAVKKDKPLEIEQLVHISQTELLQLNQLVAVLIAEKRAATEEELATLLQAQQAVDIAMFGRMLAGKTQYNGEAAVQVAHALGVHASVIEDDYFTAVDDLNQDDSGAAHIGELGFASAVFYQYICIDRELLKRNLAGNEALTQQSIKALIEAALTVGPSGKQNSFASRAYAHYALVEKGDRQPRSLSLAFLNAVNGDSYATDATQALVQVRDNMDKVYGPCAAERSEFNVIAGTGSLQELVRFSVE
>NZ_CP014222.1|WP_082752878.1|167411_167978_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MRLQLSDEQKKTLRLWWRSLQAREKGDPPLPQFNHQGRGERAKLRRCQTPEDVLLQASLHHLALALFASDKPKPQQLLDLALVAGILSHVDQDDFAHKFAASLGSKKADRPAMSEMRFQQLQTSRDPDDFYRQLRRAVDLLGNKLDVIDLAQSLFDWCHEQRENVEPAKRLKLRWATDYYTASLTKNA
>NZ_CP014222.1|WP_046350955.1|165853_167431_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNLLDQSNAWLSFRLQDGSVSKGSVYDILMTDRIDIVSPRADFRGALYQFLIGLLQQAMPPADINTWHVLYTQPPTLDELMQAFQPLLGAFEVLSDDAAFMQDWDQLADVKPIGIENLLIDLGSDSNLFFNKTSQWAGLCEGCAAQALLTLQINAPSGGVGHRVSLRGGGPLTTLLLPQEPNASLWQKLWLNVIPTSSLPSEAAQEMPLASSLPWMTPTRDSKQGNPTTPEDVHYLQAYWSMPRRIRLDKQNTNVGPCEICGEHHEILISQYRTRNYGTNYAGAWQHPLTPYSFDAKNEKPPNPVKGKRGSSTYRQWLSLTLASADDASKPAGVVQDYSRYKGRRLRLSAPPRLWCFGFEMDNMKAKCWYDTALPLFDIAGDERQFGNVVSALLDVATEAAKQLSEQVKQARNASAREPMIELDFWQQSEAGFYALLDILAAMPDLSDEELLAPLYCKWLLTLKKLCERLFEQWVLDVPIEEMDMQRVIKAKADLSKWLRLAKPMKKLWDIVNTYQKENHATATE
>NZ_CP014222.1|WP_046350954.1|163093_165814_+|CRISPR-associated-helicase/endonuclease-Cas3
MSQTKASYWRYWGKAKPHGSGSAWHLLPYHALDVAALMDCLLAQRKTWLNNLASKLGWSVGQLHDALVFFAALHDLGKFARAFQCLFDHHSPDLVPIVQSKRYDHRHDTLGLLLWLDVLRDRVPESVLQDAASDSWDIFFKIVCGHHGHPPVDDLPFGAADDYFCAEDMDAALAFILDVAGFLLASSLPAFNSTQEEILKEASWALAGLMVQADWLGSNQDFFPYHDRAGSLEEYWRMTALPAAAHALVASGTIEKQLQPYVQNEAIQAVFPSLKQPQLTPLQQYAATVPLATGPQLFMLEDVTGAGKTEAALILAHRLMAAGLGDGLYFALPTMATANQMYKRVGEVYRSFYQKGERPSVVLAHASRHLIDAFRQSVSPKDVAYSLDESTASMVCNAWLADSSKKALLADVGVGSIDQALLAILPVRHQSLRQLGLANKVLIGDEIHAYDDYVYTLLCRLLENQARQGASVILLSATLPSTMREGLANAYRRGLKLPAIELLSHLPYPLISHIHQTAHTQPCDTRQEVKRRVKVQFLNDEASVIALIAAKASSGECVCWIRNTVEDARRAFSALETIVDKGHLHLFHSRFAMGHRLDIENSVLDIFGKKSTAEQRCGQVLIGTQVLQESLDIDVSNMISDLAPTDLLIQRAGRLQRHVRKVNGDLNPQGSEGREPPVLYIYGPEPSQKPEANWYAAVFPKGQFVYPNTGQLWLTQQALLQAGCIVSPGEMAEPGAVRQLVEAVYSEEAQIPEALEKATLECMGVAKSEISMAKFNALDLPKGYCRQSSERWAEERNVPTRLGDETQTVYLLCVAVEGLQPLYSSETDFPWEMSALRVDSKKLSHLSPQWKQRFAADLDALSAHAPDKYAVLLPLIAEQGELIGEVQDKGGKVISVRYSQHLGLLM
>NZ_CP014222.1|WP_046350953.1|158883_162849_+|non-ribosomal-peptide-synthetase
MILRGPFLPELLRAETLADLLESTAQRIPDHPAIYWQSEVLSYSELNRRADLAAHHLIQFGVKAGQIVGLCLPRGAALLIMQAAIAKAGAAWLPFEADTPVDRMQVCLEDAAALLLVGDGDLAGVGVPVLSSAQLSVPLAGDLLRRQGLLPSHPAYVIYTSGSTGKPKGVPIRQGSICHFLRSENSVLGVRQDDKVYQGFSVAFDMSFEEIWISYLVGASLWLAPKILTGDPDALPAILNQEKVTVLHAVPTLLALFSQEVPSLRIINLGGEMCPESLVERWATPERQVFNTYGPTECTVSASLAQLRRGEPVTIGKPLPNYGLLVRSEDGCLLPQGETGELCIIGPGVADGYLGRPDLTAEKFFDNPFSNLEEFPHEIRLYRTGDLARIDEAGQVQCLGRTDDQVKVRGFRVELGEIEASLCQIAGVGTAAVLLRELAGIDQLVAFVVAETSDAAALKNELKRSLPPYMIPARFEFMSELPRLTSGKIDRKTLKTRELIVPTGKNMESDEPVSDAEKALFAALCTLFPGQALRLVDDFFGELGGHSLLAARLVSILRRNPAYAGMTVQEIYQSRTLQVIATRLDALAHSQPEQVEIEPIRKVPFLRRLLCGSAQLATLPFLIGLRMLLWLAPFFTYHFMTGEEGDSLGLAVGVSILVYLGSLLFSFAIAITGKWLILGRLKAGRYRLYGLMYFRWWLADRLSDITPLYFLTGSPLQSLYLRALGASVGKNVSLSAISVRAYDLLSIGDGASIGASVNFENFRVDADHWEVGPISIGKDAYIGSYTVLQSDTHVADLGRLEGLSALSRGQKIAAAEVWNGSPARLSTDSVPDVPARPVRHSFLRGLNGLAYAGGSALVAILFFVPVFPSFLLIDWLDAHWFDLTEQGVALPEAFMFYLMLALPASAVLIILTLLGSAAVRWLLLPRNPLGSWPVFGAMYYRRWLTNQIQESSLNILHGLYASVYAGWWYRLLGAKVGRGTEISNAIGVVPDLLTLGEDSFIADAVMLGDEEIDRGWMTLRATVVGNRSFVGNGAYVPDGSIIPDDVLIGVQSRAPANDRMRSGQTWLGSPALSLPAREQVSGFADSLTFRPSLARRLARGFVEALRTVMPLAVIITVGYLTVLKVMPFAEREDFHGVFWALMMAGVLYGVGSFVFILVLKWLMIGRYRPHSAPMWTSFVWRSEALTSLYESIAVPNFFNFLRGTPWLPMAFRCMGCKIGSGVFMDTTDITEFDCVSIGDDTVMHAWSGPQTHLFEDRIMKIGRVEIGSGVNVGPRSTILYDAVVGNGARLGPLTLVVKGETIPEGQAWTGSPAVPWRTCRS
>NZ_CP014222.1|WP_046350952.1|158071_158737_+|DNA-alkylation-repair-protein
MTSFQEHIRSAMQAIADDSAAIAMRAYQRDQFEFLGVAAPARRAATMPFIKALQPSSAEALIAEAQGLWNLPQREYQYIAIDLLARHVKVLTGADIPGLLSLVQQKSWWETVDGLVKVIGAIAKADKAQQSQMDAALLHPDFWIRRIAMLHQLGWKSETDLTRLQNYAKQLAPESEFFIRKAIGWALREYAWHDPAAIRVFLAEMGDQLSPLSRREAGKHL
>NZ_CP014222.1|WP_082752527.1|173711_174071_+|DUF1294-domain-containing-protein
MFTKLMVLFIIIFCGFLLFELVLGNLPWWIAGGYLLMSTVAFIAYALDKSAARNNRWRTPERTLHLLGVLGGWRGALLAQRVLRHKSAKVVFLRVFVATIVLNCAALACLLAVGGFWQG
>NZ_CP014222.1|WP_052746478.1|174135_174768_-|PEP-CTERM-sorting-domain-containing-protein
MNFTKSILATALFFAASTSFAAVTSTFVNSEKISYQNHEHAQPDTVKYDGTTELASFNWGLHHADETAQVLIKRNAGVTGEISIQNGFNFTAVSSSTDAAAARLKVGQTQDIKKGQFALFQGTFTDFSTAGDTQIGSWYDFSADNTHTFSNLVKGAAYYYLIKGSVVGTAGANYTLSSVAAPVPEPETYALMGMGLIGLLAARRRKASRA
>NZ_CP014222.1|WP_052746479.1|175133_176408_-|hypothetical-protein
MKPLPLLLLISTLLYSLCSYFQNGIPASYWDWRHELVLLSGVQLMTVMSAAMLLATRPAWLEKTLSGLDKMYGLHKQLGIAAGILLATHWLIKLSPKLIIAMEWAAPRIKRSGGIKDPLVSFAKDVGEWAAWAVLAMVILALLRAVPYRFWRKVHKLFAPLFLMGAFHGLILMPRTMWLTPVGALLAALLISGSICAIYSLLGKIGKSRQVNGHISQITPLPANQLEVICQMDSNWPSHQAGQFALVSFNQSEGAHPYTIASAPRQNGELRFIIKALGDYTRTLAQDLKVGGKVKVEGPYGCFDGEANSPRQAWIAGGIGVTPFLAWLESPDFKGQQIDFYYCVKSAKDAARLTEIQAACHAKNLRLHLIESDTGQRLNIAVINAETLDDIWYCGPQSLGKAISQHLAKMSNPPRFHHEVFAMR
>NZ_CP014222.1|WP_156455088.1|176575_177379_+|TonB-family-protein
MNIAVSHDSQRHSSWLWYGLAASILVHLLFLLLPAAAPKALPKQSGSQEIQLQLQPKPAPAPKPTPEPTPIPTPPPVMTKVPPKVPVKKDYSVPARPASQVATKAVPSKEVVIDDLGEALAGKPSKQPAELITRYADLKPREEDQQENGATRAQQSVDTQALFNIWEPQIRKKVERIGQMNFPKDEYGRSMFGTLQFRLVLNGDGNIASLTLEQSSGNPALDAAALQIVRRSATFGPVPVPLLDKRGQIMLLRYYQFINERAAWGRS
>NZ_CP014222.1|WP_156455243.1|178043_178397_+|translation-initiation-factor-Sui1
MKNALGSLVYSTEHGTMCPDCSQPKDACICKKQPRPAGDGVVRVSRETKGRKGKGVTLIKGVPLDDDELAVLAKQLRTRCGSGGTVKDGVIEVQGDHCDVVLEFLKPRGWVVKRAGG
>NZ_CP014222.1|WP_046350963.1|178843_179713_-|LysR-family-transcriptional-regulator
MQWQGIVEFISVAETQSFTLAAQKLEMSVAQVSRQVSALEQRLAARLLHRTTRKVSLTEQGQLYYQYCRPLLDGLHEAELALLQTQDKPVGKLRITAPVYYGETVVAPILHQYLIDFPQLNAELLLDNRKADLVADHIDLAIRLGPMDESSLMVTQLGSRIHHVCASPQYLDQYGTPHTLAELKQHQCLIGAVNMWRFKEGMQHREISVNGRLRCNSGSSLVQAALKGLGLVQLPDYYVDTYLQSGQLISVLEPFALTDGIWAIAPRSRFIPPKVSRFIEYLKAALLAE
>NZ_CP014222.1|WP_046350964.1|180324_181443_+|S-(hydroxymethyl)glutathione-dehydrogenase/class-III-alcohol-dehydrogenase
MKMLKTRAAVAWGPNQPLVIEELDLMPPQKGEVLVRIVASGVCHTDAYTLSGKDSEGIFPVVLGHEGAGVVEAIGEGVTSVAIGDHVIPLYTPECGECKFCLSGKTNLCQKIRATQGRGVMPDGTTRFYKDGQPIYHYMGTSTFSEYTVLPEISLAKINKEAPLEEVCLLGCGVTTGMGAVMNTAKVKAGDTVAIFGLGGIGLSAVIGARMARASRIIGIDINTSKFELAKQLGATDVINPKDFEKSIQDVIVEMTDGGVDFSFECIGNVNVMRSALECCHKGWGESVIIGVAGAGEEISTRPFQLVTGRVWRGSAFGGVRGRSELPSFVDRYMKGEFALSDFITHTMPLEEINTAFELMHEGKSIRSVIHF
>NZ_CP014222.1|WP_156455089.1|181844_182690_+|S-formylglutathione-hydrolase
MVMSLELISSNRSFGGWHKRYKHQASSTSCEMTFAVYLPPQTAQGGKVPVVYWLSGLTCNDENFATKAGAQRVAAELGIALVMPDTSPRGSDVADAGRYDLGQGAGFYVNATEAPWQRHYQMYDYIVSELPALIEAHFPVTNRKSISGHSMGGHGALMIALRNPQAYLSASAFAPIVNPSQVPWGETAFSEYLGDDRSTWLAYDSCHLMQHATQMLPLLIDQGDQDSFIPQQLQPNALEKIARTRQWPFTLNIQPGYDHSYYFIASFIETHLRFHADHLGA
>NZ_CP014222.1|WP_046350966.1|183188_183716_-|inorganic-diphosphatase
MDISKIAAGKDLPNDFNVIIEIPANAPPIKYEFDKASGAIIVDRFVGTSMSYPMNYGFVPHTLSLDGDPVDVLVHTPFPLLPGMVIKCRAIGVLGMEDEAGMDAKVIAVPVEKVCAMYAHIQKLEDLPELLLAQVKHYFEHYKDLEKGKWVKITGWGDKAAAHAEIMESYDRAQK
>NZ_CP014222.1|WP_046350967.1|183989_186671_+|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase
MKPHYLSPLFDPRSVAVIGASETPGAVGSTVFANLLDGGYTGKLFPVNLHRDQVLGINAFKTLAKVPMVVDLVIITTPAKTLVDLIEECGKKGVKAVVIMSCDFVGTDKKSQTQLDKIMDRARHYGIRIMGPTVFGLCRVSSKLMAGNYQGKLKNGSMALVSQSSSITSAILDWAESHDVGFSSVVSLGSAVDVDVGEVLDYLVADPKTQSILLYIEDLQEARTFMSAVRAAARSKPVMALKVGRYNDVSAAHGRTHSERLIGRDDVFDAALKRAGVLRLRSINQLFTAAKVLNGTFKTKGRRLAVVTNGIGAGMMAVDRARDLHVLLPELAPGTVAWLAKNLPAQASRNNPVDILGDASPERFKLVVEAVLADPNIDGVLVVFTPQAGTDHLRTAEAMIALKKTSDKPLLMAWIGGKKVDASRKLLNKAGCASFSAPEHAVEVFYSLAAWQHNQQLLLQTPPPLGEWEAPDMETAHMVIDKVLADGRSLLDEIESKAILRAFHIPVAMTVRANSADDAVNAAMGMGLPVVLKVDAIDLMHKTDIDGVALNLNSLIAVASEANKMLSRAHDKLGIERVRGLTVQPMHGKKHARELMVGVVNDSAFGPVISFGAGGIAVEVFNDIAVSLPPLNDYLAEHLIRRTRIKKMLAPFRNQPAVNIEAVKNVLLRVSEMVCELPQIQQLDINPLISDENGVIAVDASIIVAAVDPKARRYAHMAIHPYPSHLMQLTQLKTGMPMILRPIRPEDAELLIQFVSRLSDETRYNRYMSVLKSLPQSLLARFTHLDYAREMAIAATVQAGQGEQIIGVARYTANPDKDSCEFAVVIDDAWQGKGLGNRLMEALFTAARDMGLSIIEGEVLTSNKTMLAFMKHLGFTIQTHPEDNGLKWVVKEL

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Crispr_ID: NZ_CP014222_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014222_2

3002601-3002686

Orphan

Consensus_repeat	Method
CCTCGCCCGGCGGGTGAAGGCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014222_2

>merge|NZ_CP014222|2|3002601-3002686|CRISPRCasFinder
CCTCGCCCGGCGGGTGAAGGCCGTTTCAATAACAACCCACGCGGTGAAGCACGCCCAGCAACGCCTCGCCCAGCGGGTGAAGGCCG

>NZ_CP014222|2|2|3002601-3002686|CRISPRCasFinder
CCTCGCCCGGCGGGTGAAGGCCG	TTTCAATAACAACCCACGCGGTGAAGCACGCCCAGCAACG
CCTCGCCCAGCGGGTGAAGGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014222.1\|WP_046352368.1\|3007340_3007916_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP014222.1\|WP_046352607.1\|3008018_3008564_-\|nucleotidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|377593
NZ_CP014222.1\|WP_046352367.1\|3006927_3007290_+\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|239274
NZ_CP014222.1\|WP_046352365.1\|3005143_3006220_+\|ionic-transporter-y4hA	unknown	unknown	gnl\|CDD\|223464
NZ_CP014222.1\|WP_046352370.1\|3009284_3009806_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP014222.1\|WP_046352359.1\|2995453_2996791_-\|gluconate-transporter	unknown	unknown	gnl\|CDD\|182485
NZ_CP014222.1\|WP_046352361.1\|2997716_2998718_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|184949
NZ_CP014222.1\|WP_046352357.1\|2992232_2993222_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP014222.1\|WP_046352358.1\|2993378_2994296_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP014222.1\|WP_052746634.1\|2989741_2992081_+\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|340419
NZ_CP014222.1\|WP_052746635.1\|2994428_2995367_+\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191
NZ_CP014222.1\|WP_046352608.1\|3009823_3010246_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP014222.1\|WP_046352360.1\|2996797_2997340_-\|gluconokinase	unknown	unknown	gnl\|CDD\|236926
NZ_CP014222.1\|WP_046352356.1\|2988972_2989716_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366132
NZ_CP014222.1\|WP_046352366.1\|3006273_3006780_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370137
NZ_CP014222.1\|WP_046352364.1\|3004090_3004672_+\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl\|CDD\|377877
NZ_CP014222.1\|WP_046352363.1\|3003090_3003810_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|316372
NZ_CP014222.1\|WP_046352355.1\|2988221_2988944_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270422
NZ_CP014222.1\|WP_046352369.1\|3008599_3008977_-\|steroid-Delta-isomerase	unknown	unknown	gnl\|CDD\|226913
NZ_CP014222.1\|WP_046352362.1\|2999310_3000696_+\|ATP-dependent-RNA-helicase-DbpA	unknown	unknown	gnl\|CDD\|236977

Protein	Function_ID	Function_description	E-value
NZ_CP014222.1\|WP_046352368.1\|3007340_3007916_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.97677e-28
NZ_CP014222.1\|WP_046352607.1\|3008018_3008564_-\|nucleotidyltransferase-family-protein	gnl\|CDD\|377593	pfam06042, NTP_transf_6, Nucleotidyltransferase. This family consists of several hypothetical bacterial proteins of unknown function. This family was recently identified as belonging to the nucleotidyltransferase superfamily.	3.10799e-75
NZ_CP014222.1\|WP_046352367.1\|3006927_3007290_+\|glutaredoxin-family-protein	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	2.55508e-13
NZ_CP014222.1\|WP_046352365.1\|3005143_3006220_+\|ionic-transporter-y4hA	gnl\|CDD\|223464	COG0387, ChaA, Ca2+/H+ antiporter [Inorganic ion transport and metabolism].	3.40672e-65
NZ_CP014222.1\|WP_046352370.1\|3009284_3009806_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.67869e-14
NZ_CP014222.1\|WP_046352359.1\|2995453_2996791_-\|gluconate-transporter	gnl\|CDD\|182485	PRK10472, PRK10472, low affinity gluconate transporter; Provisional.	0
NZ_CP014222.1\|WP_046352361.1\|2997716_2998718_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|184949	PRK14987, PRK14987, HTH-type transcriptional regulator GntR.	2.92794e-122
NZ_CP014222.1\|WP_046352357.1\|2992232_2993222_+\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.46109e-62
NZ_CP014222.1\|WP_046352358.1\|2993378_2994296_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.55921e-78
NZ_CP014222.1\|WP_052746634.1\|2989741_2992081_+\|GAF-domain-containing-protein	gnl\|CDD\|340419	cd16943, HATPase_AtoS-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS. This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.	3.73199e-36
NZ_CP014222.1\|WP_052746635.1\|2994428_2995367_+\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	3.48836e-148
NZ_CP014222.1\|WP_046352608.1\|3009823_3010246_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	9.08717e-08
NZ_CP014222.1\|WP_046352360.1\|2996797_2997340_-\|gluconokinase	gnl\|CDD\|236926	PRK11545, gntK, gluconokinase.	1.82023e-104
NZ_CP014222.1\|WP_046352356.1\|2988972_2989716_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|366132	pfam00497, SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.	4.866e-25
NZ_CP014222.1\|WP_046352366.1\|3006273_3006780_+\|hypothetical-protein	gnl\|CDD\|370137	pfam08816, Ivy, Inhibitor of vertebrate lysozyme (Ivy). This bacterial family is a strong inhibitor of vertebrate lysozyme.	3.54144e-16
NZ_CP014222.1\|WP_046352364.1\|3004090_3004672_+\|PEP-CTERM-sorting-domain-containing-protein	gnl\|CDD\|377877	pfam07589, VPEP, PEP-CTERM motif. This motif has been identified in a wide range of bacteria at their C-terminus. It has been suggested that this is a protein sorting signal. Based on phylogenetic profiling it has been suggested that the EpsH family of proteins mediate this function.	1.57303e-06
NZ_CP014222.1\|WP_046352363.1\|3003090_3003810_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|316372	pfam13847, Methyltransf_31, Methyltransferase domain. This family appears to have methyltransferase activity.	4.89558e-10
NZ_CP014222.1\|WP_046352355.1\|2988221_2988944_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270422	cd13704, PBP2_HisK, The periplasmic sensor domain of histidine kinase receptors; the type 2 periplasmic binding fold protein. This subfamily includes the periplasmic sensor domain of the histidine kinase receptors (HisK) which are elements of the two-component signal transduction systems commonly found in bacteria and lower eukaryotes. Typically, the two-component system consists of a membrane-spanning histidine kinase sensor and a cytoplasmic response regulator. The two-component systems serve as a stimulus-response coupling mechanism to enable microorganisms to sense and respond to changes in environmental conditions. Extracellular stimuli such as small molecule ligands and ions are detected by the N-terminal periplasmic sensing domain of the sensor kinase receptor, which regulate the catalytic activity of the cytoplasmic kinase domain and promote ATP-dependent autophosphorylation of a conserved histidine residue. The phosphate is then transferred to a conserved aspartate in the response regulator through a phospho-transfer mechanism, and the activity of the response regulator is in turn regulated. The sensor domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space through their function as an initial high-affinity binding component. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.10232e-09
NZ_CP014222.1\|WP_046352369.1\|3008599_3008977_-\|steroid-Delta-isomerase	gnl\|CDD\|226913	COG4538, COG4538, Uncharacterized conserved protein [Function unknown].	2.04863e-29
NZ_CP014222.1\|WP_046352362.1\|2999310_3000696_+\|ATP-dependent-RNA-helicase-DbpA	gnl\|CDD\|236977	PRK11776, PRK11776, ATP-dependent RNA helicase DbpA; Provisional.	0

>NZ_CP014222.1|WP_046352362.1|2999310_3000696_+|ATP-dependent-RNA-helicase-DbpA
MNTTSFANLPLSPAMLQNLDSLGYVEMTEIQAQSLPLILARRDLIAQAKTGSGKTAAFGIGMLHKLNPSYFAIQGLVICPTRELADQVAKELRRLARFTENIKILTLCGGTPMGPQIASLVHGAHIIVGTPGRLRDHLGRASIDLSTVQTLVLDEADRMVDMGFYDEIAGIVSACPTRRQTLLFSATYPDNIRKDSAKFLKLPAEVKVEAQHADSQIEQRFYSVEHEERNAAVAQLLNHYKPVQTLAFCNTKIHCRELAAELRDQGFSALALYGELEQRERDEILVQFSNQSCSILVATDVAARGLDIQSLGAVINVDVSKDTEVHIHRIGRTGRGHDKGLALSLAAPNEKKWVTLIEEYQGGPVRWFDLEKLEPAEGGPLRPPMVTLCIMGGKKDKLRPGDLLGALTGDAGLTKEQVGKINVFEFLTYVAIDRRVANKAFNSLSQGNIKGRSFKMRFLGE
>NZ_CP014222.1|WP_046352361.1|2997716_2998718_-|LacI-family-DNA-binding-transcriptional-regulator
MNHKARRPTLQDVADKVGASKMTVSRYLREPQQVAEATAKKIAVAMEELGYIHNRVPDMLANAKSRAIGVLLPSMSNQVFSSVVRGIESVSGPAGLHALYGHYGYSMEREEQQIAQLLSFNVDGLILSETQHTDRTLRMLETAAIPVLEVMELPEHPVDLAVGLNHTAAAKEIVGLMIARGRKRIAYLAARLDHRTRQREAGYLAALAEAGLTPVLIHTDQPSSFTLGGQLLRNALQAAPDLDGVFCTNDDIAAGALLACQAMGLSVPAQISVAGFNALDIGHALAPQLASVITPREAIGRVAAERLIGRMEGKVYPDRVLDMSYDIFLGQSL
>NZ_CP014222.1|WP_046352360.1|2996797_2997340_-|gluconokinase
MSQIDQVIPHQVFVVMGVSGSGKSAVGSAVSRVLDCGFLDGDFLHPRANIDKMASGQPLNDDDRAPWLGALSTAAYAMQRTQTISVIVCSSLKKAYRDILREGNPNLSFIYLGGTFELIESRLKARQGHFQKPKMLVSQFATLEVPGSDEPDVVHIDIDQSLENVVAAAVQHIRAITAQE
>NZ_CP014222.1|WP_046352359.1|2995453_2996791_-|gluconate-transporter
MDTLTLLVTAIGSVLMLLFLVMKARLHAFVALMLVSIAAGIGSGMPLDKIADTMQKGMGGTLGFLAVVVALGAMFGKILHETGALDQIAVKLLDLFGQSRANYALGIAGLICTLPLFFDVAVVLLIGVVFAVARRTGGNVVKLAIPLFAGVAAAAAFLLPGPTAMLLASQMKADFGWMIVLGLAAAIPGMLLAGPVYGNFISKHVHLPLPADVSEPSLGKGQMPSFGFSLALVLFPLILVGLKTIVARFVDPSGTAYQWLQLIGHPFIAILAACLLAIYGLALRRGMSKDKVMEVCSAALQPAGIILLVTGAGGVFKQVLVDSGVGPALGNALIGAGLPIAVACFVLAAMVRVIQGSATVACLTTVGLVLPVIELAGYSGAQLAALSVCIAGGSIVLSHVNDSGFWLFGKFTGANELQTLKTWTVMETILGTTGALVGMAAFSML
>NZ_CP014222.1|WP_052746635.1|2994428_2995367_+|NADP-dependent-oxidoreductase
MTTSMQAIRQHSYGQRDVLQLENVPTPQINADDVLIRVHAAGVNPVDWKIREGYLQSMLTYEMPLTLGWDVAGEIVALGEHVTGWQIGDAVYSRPDIARNGAYAEFVAVRASEIAKKPQSLDWQQAAAVPLAALTAWQALFEIAKLQAGEKVLIHAGAGGVGLFAIQLAKWRGAEVYTTTSGKNAELVSAHGADHVIDYTQANFADLRDLDVVFDTMGGEILAQSWQTLKVGGRLVSICDEPDAATAQKHQVNAHFCFVQPNAAQLSEIAALLDAGHIKVVIDSVFPLAQAALAHERSESGRARGKIVLQVV
>NZ_CP014222.1|WP_046352358.1|2993378_2994296_-|LysR-family-transcriptional-regulator
MTLSLDTLPGLALFSCVVRHGSLTGAAQELGLNRSSVSKQLARFEAQLGAKLLQRTTRKLALTELGERVWQEAQTVAAALGNIDAITDDYRQNVRGRLKVSCSSSLARVHLVPLLPLFSQRYPEVDLLLQLEDRFVDLTTEQVDIAIRVGHLPDSSLVARKLGELQWQLVASPSYLAQHGAPQTPSDLVQHACLFYQNGLRAMNLWTFSGPLGEEQVRVKGPLAMNDACALVDAAINGLGILLIDRALLAAPLASGQLLALLPDYQLAAGLPVYAVYPARDWLPAKATAFVEFIIKEFSPRLLVR
>NZ_CP014222.1|WP_046352357.1|2992232_2993222_+|diguanylate-cyclase
MATILCVDDDSSVLNALRSLLGQRLRHDQSVELAENGAEALEIIAELAQEGRELSVIIADYIMPGMKGDELLVQVHQQLPKTMKIMLTGQSDLNGVKRTINEANLFRFLEKPWQNEDIVLTVQAAIHAYELDNKLQQKNQELLRINEELENRVNERTQQLQEKNRELEQLAITDRLTGLYNRLFLDQVLEREFTSAGRHSTTFSLILVDIDHFKKVNDSYGHHMGDEVLKSISRILKETIRASDLLGRWGGEEFLILCPKTQLKDAAKVAEKLRLAIEHYDFASIGCRTASFGVACYKNGDTIAMVEARADKALYLAKDQGRNRVVSSG
>NZ_CP014222.1|WP_052746634.1|2989741_2992081_+|GAF-domain-containing-protein
MPRIGQSGLSLGSRIVLATLAFCLVFTLVAVAIKTWSAWQVNLAAMRAELSLIEQVYQHTLSKAIWEMDRETLRTHLTSASKVSSLGQIVITITPEQLAAETFVFTQPGWQASNIAPSRQLILNYHPFSGAAGQQVGKLVLSGDERVLWARLRSEVAAIIWTQGIQSLLLAGFIMLIFNRSVTVHVQRIARHLAQLNPDNLNQALLMPRDSSRQDELSMLVSGVNNLQSNLSGYLQQKQQYEEELAKHRDHLAERVGERTAELFEANKALASSADTLRQLGDIGRELTTSLNPHAICLTLYQHLRALLPLDAFTVALLASEGDRLNLIYYIEDGRVANPAILMLDHPSSLSVRAFREEQELIIADAALIEKAPSPENIKPSAPMRSVVLRPLIVNSQRIGVVSIQSHTANAFQERELEILRSIAVYAAIALANATAYAAAETSREQTANALETLRQAQSQLIQSEKMAALGQLIAGVAHEINTPIGAVKSSGKNIADSLSHALENLPRLFQILTEIDQQRFIQLISYKPEHVLSHREERSKVRTLNQELEAENIEDAHYKAGILVQLHAENSLAEYLPLLQHPDHGLILDTAYSISSIVSNTDNINSAVEQVSKIIFALKSFSRFDHEGVSTEAHLKDGLETVLTIYQNQIKQNIELIRHYEDIAPIVCFPDELNQVWTNLIHNGLQAMQYKGVLKIEISRTENEARVAISDSGCGIAENIRPKIFDAFFTTKPIGEGSGLGLDIVKRIIHKHHGRIEVQSEVGLGTTFLIYLPYLRPS
>NZ_CP014222.1|WP_046352356.1|2988972_2989716_+|transporter-substrate-binding-domain-containing-protein
MRWLKKCFLFIALNLTLHTASAEAIKIVTEELAPYNFTEKGVLTGFSTEVIQAILKEIKIQGDFQSMPWARAYDTALNHENILIYSIGRTAQREKLFKWIGPIAPANNYLFSLANHNIKINHLNDAKKYQIGSVNADIGEQFLESQGFIKGTNLQSSVKYLLNYEKLKRGRVDLWVMNEMAAYHLVRQFGDDPNKVLSKAYRLDLIGDGYFMAFNHKTSDEMVERFRQGLNTIKKNGTFDLIKKKWL
>NZ_CP014222.1|WP_046352355.1|2988221_2988944_+|transporter-substrate-binding-domain-containing-protein
MKAIALLALSTLLSTTYAETIHAVTETTLYSYLKEGQVAGPATELLKLNLQRAGLTDYNIHLYPWARSYEIAQNRANVLIYPIVRTPSREKRFKWIGELIKTQYHFYKLKARKEIIVNNLSDAKRYTIGVIRNDVRQDYLQQQNFTRLTISAQREDNFKQLINKQIDIIPLIDKDAEALCQQLAFDCAKLERIYTLNGISNGLYIALSKSTPDPLVEKMRSAFEQLKAEGLVKKIIEKNQ
>NZ_CP014222.1|WP_046352363.1|3003090_3003810_+|methyltransferase-domain-containing-protein
MTRNHPKLPENPYYEGVPDYMTEVYDWAYVNPRRVNQLDHNLVVKVLLFGNDQRLMRAYLNEIQPGMKVWQVAHVYGDLVRKVAQKVGPDGCFHLTDITPAQIEHGQAKLAIYPWAKVIRADAANYQCDKSFDLICSFFLLHEVPDDKKREIIDHMLSKMPEGGKVLFVDYHRPSLWQPIRWILKWVNAKLEPFAEALWQNEISHYASHADQYHWQKRTIFGGVYQIVAVTRTTPAAQS
>NZ_CP014222.1|WP_046352364.1|3004090_3004672_+|PEP-CTERM-sorting-domain-containing-protein
MLQTKLLISCAIFALSSFANATVIDFNHLAHNDTSQVFSTISSNGFVIKNDSQANDRLGIWGKNDEFQADTGRAAVFVNYSGSKTSIEHANKSFFNFKSIDLADVFNNGDSATIQFSFFNGQSTTFETVILDQLKGLQTIFFNKNNLTRVSWVGSNSQFDNINVSAPVPEPETYALLGMGLMSLWIARRRKHA
>NZ_CP014222.1|WP_046352365.1|3005143_3006220_+|ionic-transporter-y4hA
MKVTLPIWTIAAPIIAWALYLAPGQSLGVIYLALLTIALFGGVLAAVHHAEVVAHRVGEPYGTLVLAVAITIIEVALIVSLMMAGGPETTALARDTVFAAVMIILNGIVGMCLLAGAAQYKEQTFSLNGMSAALTTLAAIAVLTLILPNYTTSAPGPFYTSSQLIFISVVTLVLYGTFVLVQTVRHRDYFLPSHGEDDEEAHAAPPSLLETSISSVLLLVCLAAVVLLAKALAPSIELGVANMGAPKAVVGVIIAAVVLLPEGLAALRAARANRLQTSLNLALGSALASIGLTIPAVALVALMSGLTLTLGIDIKSTVLLLLSLFTTMLALGTGKTTVLPGVVLLVIFAVYLFVTVIP
>NZ_CP014222.1|WP_046352366.1|3006273_3006780_+|hypothetical-protein
MQWINRISISSTLIAALFIPLSAQAKNINSKDALACVESSKCAYFFDVYAGDKLLRQELSKVFKTAGMPSPRWLGKGVSTPMTPITLAQKPYLLGSVCQPHNCGHLVSVLYSPEQKRVVAHYKPEEGAAKWLGVPNATEQQILNEFETADSPLQKKLDSHPKLPIIIN
>NZ_CP014222.1|WP_046352367.1|3006927_3007290_+|glutaredoxin-family-protein
MARVIMLLMIAGALQFAWKHYGTSRSNTEYSSTKMSQLASAVKPGEVTMYSTTECFYCVEAKSWLNQNGFAFTECNMTIDPRCQQEFNAYGAIGTPFLIVRGHQMKEGFSTDEFLQALSS
>NZ_CP014222.1|WP_046352368.1|3007340_3007916_+|GNAT-family-N-acetyltransferase
MSINPILLDFPDHFSSKRLMMRCPQAGDGELVFAAINESIHALRRFPASLPWAVFEPSVAASESYCRDSHAQFIARSDLPFLIFLKESGQLIGAAGLVRMDWNVPKFEIGYWCRTSLQGYGLITEAIHAISQFAFEHLNARRLEIFADDLNTASWRVAEKVGFEFEGILRNEKIDPDGTLRNTRVYAKISL
>NZ_CP014222.1|WP_046352607.1|3008018_3008564_-|nucleotidyltransferase-family-protein
MNFHQQLTLWLKADHLRCQVLLQAAELGLPDWCIAAGFVRNLVWDQLHDYAEPTPLADIDLIYFNAEDMSEEADRVLEQRLRQDSDLLWSVKNQARMHSRNGDASYLNTLDAMSYWPELETAVGVRLEPDESFISPFALENLSHLQITLNPKRPKIADFEARISQKKWLEIWPKLQVNRGG
>NZ_CP014222.1|WP_046352369.1|3008599_3008977_-|steroid-Delta-isomerase
MQSLSPVDVIQRQLDAYNAKDVDAWLATYATDAQQFALHGELLVEGHVAMGSKMLVRFAEPDLHAELLQRTVMGPIVVDYERITRNFPEGKGTVEMLCVYEVADGLIQKASFAMGEQVVIAPALA
>NZ_CP014222.1|WP_046352370.1|3009284_3009806_-|GNAT-family-N-acetyltransferase
MALELVYEIKKATQDDCLSIAKIHVLSWQYAYCDLLPSDYLAQLSVEKREATWRNALNTGSSQVLVAQSGDGLLGFISFAPCRDEDAASDQAEIWSLYVSPAHWSAGVGLALYCAAKALIQEQGFKALSLWVLAGNQRALQFYTKAGFTPDLSKTFELAGVELQELRLVQGIA
>NZ_CP014222.1|WP_046352608.1|3009823_3010246_-|GNAT-family-N-acetyltransferase
MNIETLQNPPAALFEELEEKITAFNEELWEVKTKYPLAIAARDEEGVLLAGASARTFGLWLLIENIWVSEALRGQDMGSKILAQLEAAAIERGCQFALLDTLNFQAQPFYEKFNYQVGWIQPSYPVTGCKYFMSKQLIAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP014222_1	1.16\|172721\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172721-172752	32	NZ_CP014222.1	1392846-1392877	0	1.0
NZ_CP014222_1	1.24\|173209\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	173209-173240	32	NZ_CP014222.1	2045586-2045617	0	1.0
NZ_CP014222_1	1.15\|172660\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172660-172691	32	NZ_CP014222.1	1393489-1393520	2	0.938

1. spacer 1.16|172721|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to position: 1392846-1392877, mismatch: 0, identity: 1.0

ccagcttctgaaaatgcgtctggcccaggtga	CRISPR spacer
ccagcttctgaaaatgcgtctggcccaggtga	Protospacer
********************************

2. spacer 1.24|173209|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to position: 2045586-2045617, mismatch: 0, identity: 1.0

cgcccagcccaaggtggcgcactcatacgcca	CRISPR spacer
cgcccagcccaaggtggcgcactcatacgcca	Protospacer
********************************

3. spacer 1.15|172660|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to position: 1393489-1393520, mismatch: 2, identity: 0.938

tatcaacttctaaaacacccaaaacttcaatt	CRISPR spacer
tatcaacttctaaaagccccaaaacttcaatt	Protospacer
***************  ***************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014222_1	1.5\|172050\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172050-172081	32	NC_011142	Iodobacteriophage phiPLPE, complete genome	10496-10527	5	0.844
NZ_CP014222_1	1.29\|173514\|32\|NZ_CP014222\|CRISPRCasFinder,CRT	173514-173545	32	AY539836	Burkholderia cenocepacia phage BcepMu, complete genome	16215-16246	5	0.844
NZ_CP014222_1	1.18\|172843\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172843-172874	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1969218-1969249	6	0.812
NZ_CP014222_1	1.6\|172111\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172111-172142	32	NC_011142	Iodobacteriophage phiPLPE, complete genome	10856-10887	7	0.781
NZ_CP014222_1	1.6\|172111\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172111-172142	32	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	280297-280328	7	0.781
NZ_CP014222_1	1.6\|172111\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172111-172142	32	NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	413842-413873	7	0.781
NZ_CP014222_1	1.7\|172172\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172172-172203	32	NC_048201	Pseudomonas phage 17A genome assembly 17A, chromosome : 1	29914-29945	7	0.781
NZ_CP014222_1	1.9\|172294\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172294-172325	32	NZ_CP050098	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence	733743-733774	7	0.781
NZ_CP014222_1	1.9\|172294\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172294-172325	32	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	878462-878493	7	0.781
NZ_CP014222_1	1.6\|172111\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172111-172142	32	NZ_CP017078	Novosphingobium resinovorum strain SA1 plasmid pSA3, complete sequence	244973-245004	8	0.75
NZ_CP014222_1	1.17\|172782\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172782-172813	32	NZ_KT334396	Aeromonas salmonicida strain Y47 plasmid pY47-1, complete sequence	7761-7792	8	0.75
NZ_CP014222_1	1.18\|172843\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172843-172874	32	MT310860	Mycobacterium phage Chris, complete genome	14543-14574	8	0.75
NZ_CP014222_1	1.18\|172843\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172843-172874	32	MK460246	Mycobacterium phage Nibb, complete genome	14594-14625	8	0.75
NZ_CP014222_1	1.18\|172843\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172843-172874	32	NZ_CP043960	Streptomyces tendae strain 139 plasmid unnamed1, complete sequence	315054-315085	8	0.75
NZ_CP014222_1	1.20\|172965\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172965-172996	32	NZ_MF600313	Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_1, complete sequence	271733-271764	8	0.75
NZ_CP014222_1	1.3\|171928\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	171928-171959	32	NZ_CP022517	Pantoea vagans strain FBS135 plasmid pPant1, complete sequence	285939-285970	9	0.719
NZ_CP014222_1	1.7\|172172\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172172-172203	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	94813-94844	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1671758-1671789	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1681246-1681277	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1388858-1388889	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1692726-1692757	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1583527-1583558	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1584173-1584204	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	360046-360077	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1583549-1583580	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1596800-1596831	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1577447-1577478	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1632442-1632473	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1670483-1670514	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1583549-1583580	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1583549-1583580	9	0.719
NZ_CP014222_1	1.8\|172233\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172233-172264	32	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1583549-1583580	9	0.719
NZ_CP014222_1	1.12\|172477\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172477-172508	32	AP014210	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C81-MedDCM-OCT-S26-C128, * SEQUENCING IN PROGRESS *	5622-5653	9	0.719
NZ_CP014222_1	1.14\|172599\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172599-172630	32	NC_014634	Ilyobacter polytropus DSM 2926 plasmid pILYOP02, complete sequence	8068-8099	9	0.719
NZ_CP014222_1	1.18\|172843\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172843-172874	32	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1772718-1772749	9	0.719
NZ_CP014222_1	1.18\|172843\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172843-172874	32	MT310859	Mycobacterium phage MarkPhew, complete genome	14451-14482	9	0.719
NZ_CP014222_1	1.19\|172904\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172904-172935	32	NZ_CP050125	Rhodococcus erythropolis strain KB1 plasmid plas1, complete sequence	171986-172017	9	0.719
NZ_CP014222_1	1.24\|173209\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	173209-173240	32	NZ_CP045339	Vibrio sp. THAF190c plasmid pTHAF190c_a, complete sequence	441596-441627	9	0.719
NZ_CP014222_1	1.4\|171989\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	171989-172020	32	NZ_CP039372	Pseudomonas putida strain 1290 plasmid pPp1290, complete sequence	97226-97257	10	0.688
NZ_CP014222_1	1.10\|172355\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172355-172386	32	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	786472-786503	10	0.688
NZ_CP014222_1	1.19\|172904\|32\|NZ_CP014222\|PILER-CR,CRISPRCasFinder,CRT	172904-172935	32	NZ_CP013744	Streptomyces sp. CdTB01 plasmid unnamed, complete sequence	227357-227388	10	0.688

1. spacer 1.5|172050|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NC_011142 (Iodobacteriophage phiPLPE, complete genome) position: , mismatch: 5, identity: 0.844

actcgctagttatgcggcctgttgttgaggat	CRISPR spacer
attcgctcgttatgcggcctgttgttggagaa	Protospacer
*.***** *******************..**

2. spacer 1.29|173514|32|NZ_CP014222|CRISPRCasFinder,CRT matches to AY539836 (Burkholderia cenocepacia phage BcepMu, complete genome) position: , mismatch: 5, identity: 0.844

gtcggcagctatatcgtgccgatcgatatcat	CRISPR spacer
gtcggcaactacatcgtgccgatcgacgtcgt	Protospacer
*******.***.**************..**.*

3. spacer 1.18|172843|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.812

-tgcctgaggcgtcgagcggcgtcggcctgacc	CRISPR spacer
gcaactg-ggcgtcgcgcggcgccggcctgacc	Protospacer
 .. *** ******* ******.**********

4. spacer 1.6|172111|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NC_011142 (Iodobacteriophage phiPLPE, complete genome) position: , mismatch: 7, identity: 0.781

ccatgtgtgatcgtatttttccatttttaaca	CRISPR spacer
ccatgtgtgatcgtattttttcatttcgcttc	Protospacer
********************.*****.   .

5. spacer 1.6|172111|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 7, identity: 0.781

-ccatgtgtgatcgtatttttccatttttaaca	CRISPR spacer
atcctg-gagatcataattttccatttttaact	Protospacer
 .* ** * ****.** ***************

6. spacer 1.6|172111|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016589 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence) position: , mismatch: 7, identity: 0.781

-ccatgtgtgatcgtatttttccatttttaaca	CRISPR spacer
atcctg-gagatcataattttccatttttaact	Protospacer
 .* ** * ****.** ***************

7. spacer 1.7|172172|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NC_048201 (Pseudomonas phage 17A genome assembly 17A, chromosome : 1) position: , mismatch: 7, identity: 0.781

cgacaacaagaactacaacatccgcgccctaa	CRISPR spacer
ccacgtcaagaactacaacagccgcgcactgg	Protospacer
* **. ************** ****** **..

8. spacer 1.9|172294|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050098 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence) position: , mismatch: 7, identity: 0.781

ttctgccca-cgcgaggcaagcattgcagcagc	CRISPR spacer
-gccgccggccgccaggcaagcatcgcagcagc	Protospacer
  *.*** . *** **********.********

9. spacer 1.9|172294|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 7, identity: 0.781

ttctgccca-cgcgaggcaagcattgcagcagc	CRISPR spacer
-gccgccggccgccaggcaagcatcgcagcagc	Protospacer
  *.*** . *** **********.********

10. spacer 1.6|172111|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017078 (Novosphingobium resinovorum strain SA1 plasmid pSA3, complete sequence) position: , mismatch: 8, identity: 0.75

ccatgtgtgatcgtatttttccatttttaaca	CRISPR spacer
acatgtgtgatcgggtttttccatttctgtgc	Protospacer
 ************ .***********.*.

11. spacer 1.17|172782|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT334396 (Aeromonas salmonicida strain Y47 plasmid pY47-1, complete sequence) position: , mismatch: 8, identity: 0.75

gcgtcggattttctacccagtgcaaaaactca	CRISPR spacer
gcgtcggattttctaccaagcgcagcgacagt	Protospacer
***************** **.***. .**

12. spacer 1.18|172843|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to MT310860 (Mycobacterium phage Chris, complete genome) position: , mismatch: 8, identity: 0.75

tgcctgaggcgtcgagcggcgtcggcctgacc	CRISPR spacer
ccgcgggctcgtcgagcggcggcggcctgacc	Protospacer
.  * *.  ************ **********

13. spacer 1.18|172843|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to MK460246 (Mycobacterium phage Nibb, complete genome) position: , mismatch: 8, identity: 0.75

tgcctgaggcgtcgagcggcgtcggcctgacc	CRISPR spacer
ccgcgggctcgtcgagcggcggcggcctgacc	Protospacer
.  * *.  ************ **********

14. spacer 1.18|172843|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043960 (Streptomyces tendae strain 139 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tgcctgaggcgtcgagcggcgtcggcctgacc	CRISPR spacer
agcctgagccgtcgagcggcgacgcacccaac	Protospacer
 ******* ************ **  *. * *

15. spacer 1.20|172965|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF600313 (Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_1, complete sequence) position: , mismatch: 8, identity: 0.75

gttgtttctaaatcaaccgtggctgaagtaga	CRISPR spacer
ctcgtttctcaatcaactgtggctgatggcgc	Protospacer
 *.****** *******.******** *  *

16. spacer 1.3|171928|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022517 (Pantoea vagans strain FBS135 plasmid pPant1, complete sequence) position: , mismatch: 9, identity: 0.719

gctggaaacaaattgtcatcgctggccccggc	CRISPR spacer
ccagctttgaaatggtcatcgcaggccccggc	Protospacer
 * *     **** ******** *********

17. spacer 1.7|172172|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.719

cgacaacaagaactacaacatccgcgccctaa	CRISPR spacer
gcacaccaagaactacaacatcggcttcgaac	Protospacer
  *** **************** ** .*  *

18. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

19. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

20. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

21. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

22. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

23. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

24. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

25. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

26. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

27. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

28. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

29. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

30. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

31. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

32. spacer 1.8|172233|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

cctttcaattggtggtacacattcgccaactg	CRISPR spacer
ccggcagggtgatggtacacattcgcgaactg	Protospacer
**  . .. **.************** *****

33. spacer 1.12|172477|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to AP014210 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C81-MedDCM-OCT-S26-C128, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

cgtaatcggcataatcaacaaccagattaatt	CRISPR spacer
taagatcggcataatcaacaacaagttttcta	Protospacer
.. .****************** ** **  *

34. spacer 1.14|172599|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NC_014634 (Ilyobacter polytropus DSM 2926 plasmid pILYOP02, complete sequence) position: , mismatch: 9, identity: 0.719

taaaaatatggcaacatacccataaataaaca	CRISPR spacer
aaaaaatatggcaagaaacccatactctaaat	Protospacer
 ************* * *******  . **

35. spacer 1.18|172843|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

tgcctgaggcgtcgagcggcgtcggcctgacc	CRISPR spacer
ttccggcggcgtcgagcggcgtcggtattggt	Protospacer
* ** * ******************. * . .

36. spacer 1.18|172843|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to MT310859 (Mycobacterium phage MarkPhew, complete genome) position: , mismatch: 9, identity: 0.719

tgcctgaggcgtcgagcggcgtcggcctgacc	CRISPR spacer
ccgcaggctcgtcgagcagcggcggcctgacc	Protospacer
.  * *.  ********.*** **********

37. spacer 1.19|172904|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050125 (Rhodococcus erythropolis strain KB1 plasmid plas1, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgccccagccagagcaccgcacggccaac	CRISPR spacer
cgccgccccagccagagcagcgaacgacgcga	Protospacer
  ***************** ** ***.*  .

38. spacer 1.24|173209|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045339 (Vibrio sp. THAF190c plasmid pTHAF190c_a, complete sequence) position: , mismatch: 9, identity: 0.719

cgcccagcccaaggtggcgcactcatacgcca	CRISPR spacer
taccaagcccaaggtgccgcactcattagtgc	Protospacer
..** *********** *********  *.

39. spacer 1.4|171989|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039372 (Pseudomonas putida strain 1290 plasmid pPp1290, complete sequence) position: , mismatch: 10, identity: 0.688

ctggcatcaacgaatctggcaccattgaagct	CRISPR spacer
tcgctcccagcgaatatggcaccattgaagtg	Protospacer
..* . .**.***** **************.

40. spacer 1.10|172355|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 10, identity: 0.688

acgcgatgttgatgcggtttgcccagtccaaa	CRISPR spacer
tgccgatgctgatgcggttggcccagggcgtt	Protospacer
   *****.********** ******  *.

41. spacer 1.19|172904|32|NZ_CP014222|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013744 (Streptomyces sp. CdTB01 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

gcccgccccagccagagcaccgcacggccaac	CRISPR spacer
catggccccggccagagcgccgcacggtccct	Protospacer
  . *****.********.********.*  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

328646 : 337078

Equid_alphaherpesvirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046351053.1\|328646_329615_-	serine/threonine protein kinase	A0A2P0N6E6	Equid_alphaherpesvirus	1.5e-06	26.5
WP_046351054.1\|329701_330568_+	YicC family protein	NA	NA	NA	NA
WP_156455094.1\|330637_331351_-	NUDIX domain-containing protein	G3MA14	Bacillus_virus	6.5e-20	31.7
WP_052746488.1\|331485_332385_+	ribose-phosphate pyrophosphokinase	A0A2H4YGS6	Raoultella_phage	1.5e-37	40.9
WP_046351056.1\|332381_333851_+	nicotinate phosphoribosyltransferase	A0A218KC49	Bacillus_phage	3.1e-141	54.4
WP_046351057.1\|333933_334887_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_046351058.1\|335170_335959_-	heme ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.5e-12	28.8
WP_082752540.1\|336055_337078_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.5e-14	26.9

DBSCAN-SWA_2

946478 : 957030

Tetraselmis_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046349813.1\|946478_947171_-	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	1.8e-35	38.4
WP_046349814.1\|947163_948402_-	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_156455115.1\|948643_949429_-	pyruvate formate lyase-activating protein	A0A2P0VNQ0	Tetraselmis_virus	4.4e-25	32.5
WP_082752580.1\|949597_949783_-	hypothetical protein	A0A060AHY5	Cronobacter_phage	2.8e-15	72.2
WP_046349815.1\|949874_952187_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.0e-170	42.0
WP_046349816.1\|952445_954035_-	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	1.3e-31	27.8
WP_052746342.1\|954138_957030_-	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	6.3e-21	23.2

DBSCAN-SWA_3

2046013 : 2061886

Iodobacteriophage(15.38%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046352699.1\|2046013_2046388_+	phage family protein	A0A0F6TJP2	Escherichia_coli_O157_typing_phage	4.9e-35	63.1
WP_046352698.1\|2046987_2047182_+	hypothetical protein	NA	NA	NA	NA
WP_046352697.1\|2047178_2047427_+	hypothetical protein	NA	NA	NA	NA
WP_046352696.1\|2047417_2047618_+	hypothetical protein	NA	NA	NA	NA
WP_156455166.1\|2047560_2047806_+	hypothetical protein	NA	NA	NA	NA
WP_046352695.1\|2047802_2048372_+	hypothetical protein	NA	NA	NA	NA
WP_046352694.1\|2048368_2048584_+	hypothetical protein	NA	NA	NA	NA
WP_046352692.1\|2048857_2049730_+	ATP-binding protein	A0A1B1P9H8	Acinetobacter_phage	5.7e-58	53.1
WP_046352691.1\|2049731_2050130_+	single-stranded DNA-binding protein	E1ABY7	Pseudoalteromonas_phage	1.5e-13	37.0
WP_082752707.1\|2050138_2050639_+	siphovirus Gp157 family protein	A6M981	Geobacillus_virus	6.6e-11	31.5
WP_156455167.1\|2050681_2051098_+	hypothetical protein	NA	NA	NA	NA
WP_046352688.1\|2051120_2051387_+	hypothetical protein	A0A1B0WLL0	Flavobacterium_phage	6.2e-08	38.7
WP_046352687.1\|2051442_2051790_+	hypothetical protein	NA	NA	NA	NA
WP_046352686.1\|2051800_2052307_+	hypothetical protein	NA	NA	NA	NA
WP_052746677.1\|2052303_2053212_+	recombination-associated protein RdgC	B5AX95	Iodobacteriophage	3.9e-78	52.0
WP_046352685.1\|2053226_2053448_+	hypothetical protein	NA	NA	NA	NA
WP_046352684.1\|2053740_2054280_+	hypothetical protein	NA	NA	NA	NA
WP_156455168.1\|2054450_2054894_+	hypothetical protein	NA	NA	NA	NA
WP_046352682.1\|2054890_2055145_+	hypothetical protein	NA	NA	NA	NA
WP_046352681.1\|2055240_2055918_+	hypothetical protein	R9VWB9	Serratia_phage	2.7e-39	45.1
WP_046352680.1\|2055914_2056106_+	hypothetical protein	NA	NA	NA	NA
WP_062654866.1\|2056102_2057764_+	type II restriction endonuclease subunit M	A0A1I9KFD6	Aeromonas_phage	2.1e-130	54.9
WP_046352679.1\|2057778_2058135_+	hypothetical protein	V9VCU4	Achromobacter_phage	1.2e-06	58.7
WP_046352678.1\|2058214_2058469_+	hypothetical protein	NA	NA	NA	NA
WP_046352677.1\|2058461_2058800_+	hypothetical protein	NA	NA	NA	NA
WP_052746676.1\|2058796_2059585_+	hypothetical protein	NA	NA	NA	NA
WP_046352676.1\|2059581_2059965_+	hypothetical protein	B5AX40	Iodobacteriophage	1.8e-16	41.0
WP_046352675.1\|2059966_2060332_+	hypothetical protein	Q6V7R0	Burkholderia_virus	3.8e-40	57.0
WP_046352674.1\|2060561_2060759_+	excisionase	Q774Z6	Bordetella_phage	1.9e-09	47.5
WP_046352673.1\|2060737_2061886_+	DUF3596 domain-containing protein	Q774Z5	Bordetella_phage	6.5e-78	42.0

DBSCAN-SWA_4

2711979 : 2883753

192

Burkholderia_phage(22.58%)

plate,tRNA,transposase,tail,integrase,terminase,capsid,head,holin,protease,portal

attL 2849442:2849458|attR 2879817:2879833

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046350667.1\|2711979_2713905_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_052746436.1\|2713901_2714612_-	hypothetical protein	NA	NA	NA	NA
WP_046350872.1\|2714867_2715290_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_046350665.1\|2715677_2716760_-	ribonucleotide-diphosphate reductase subunit beta	M1I8A4	Pelagibacter_phage	4.4e-44	33.4
WP_046350664.1\|2716844_2717399_-	hypothetical protein	NA	NA	NA	NA
WP_046350663.1\|2717407_2717965_-	hypothetical protein	NA	NA	NA	NA
WP_046350662.1\|2717961_2718990_-	adenosine deaminase	NA	NA	NA	NA
WP_046350661.1\|2719253_2722115_-	ribonucleoside-diphosphate reductase subunit alpha	A0A2H4P767	Pseudomonas_phage	6.2e-178	44.0
WP_046350660.1\|2722579_2723260_-	hypothetical protein	NA	NA	NA	NA
WP_156455268.1\|2723321_2724716_-	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_062654890.1\|2724745_2726155_-	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_046350657.1\|2726427_2726907_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_046350656.1\|2726911_2727379_-	peroxiredoxin	NA	NA	NA	NA
WP_046350655.1\|2727430_2728540_+	cupin	NA	NA	NA	NA
WP_046350654.1\|2728517_2729009_+	hypothetical protein	NA	NA	NA	NA
WP_046350653.1\|2729220_2729415_+	hypothetical protein	NA	NA	NA	NA
WP_046350652.1\|2729660_2730968_+	TRZ/ATZ family hydrolase	NA	NA	NA	NA
WP_046350651.1\|2730967_2731678_+	bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	NA	NA	NA	NA
WP_046350650.1\|2731716_2732370_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_046350648.1\|2733206_2735861_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_046350647.1\|2735841_2736363_+	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	9.3e-08	28.8
WP_046350646.1\|2736379_2736754_+	hypothetical protein	NA	NA	NA	NA
WP_046350645.1\|2736773_2737991_+	hypothetical protein	NA	NA	NA	NA
WP_046350644.1\|2738005_2738821_+	hypothetical protein	NA	NA	NA	NA
WP_046350643.1\|2738942_2739374_+	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_046350642.1\|2739613_2740318_-	hypothetical protein	NA	NA	NA	NA
WP_046350641.1\|2740803_2741481_+	hypothetical protein	NA	NA	NA	NA
WP_046350640.1\|2741541_2742573_-\|portal	phage portal protein	A4PE27	Ralstonia_virus	4.0e-127	66.2
WP_046350639.1\|2742575_2744327_-\|terminase	terminase ATPase subunit family protein	E5FFI8	Burkholderia_phage	2.0e-232	67.5
WP_062654892.1\|2744486_2745275_+\|capsid	GPO family capsid scaffolding protein	E5E3S5	Burkholderia_phage	5.1e-58	48.3
WP_046350637.1\|2745332_2746424_+\|capsid	phage major capsid protein, P2 family	K4NZP8	Burkholderia_phage	1.2e-100	53.4
WP_046350871.1\|2746450_2747080_+	hypothetical protein	A0A077K804	Ralstonia_phage	4.8e-51	49.1
WP_046350636.1\|2747176_2747644_+\|head	head completion/stabilization protein	E5E3S2	Burkholderia_phage	7.3e-36	51.0
WP_046350635.1\|2747643_2747850_+	hypothetical protein	A0A077K8R0	Ralstonia_phage	1.2e-14	57.4
WP_046350634.1\|2747854_2748223_+	hypothetical protein	A0A1S5NRL1	Burkholderia_phage	8.3e-19	44.9
WP_082752768.1\|2748162_2748705_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_082752920.1\|2748556_2748985_+	hypothetical protein	A0A0R6PHB3	Moraxella_phage	4.3e-19	44.3
WP_052746435.1\|2748981_2749440_+	hypothetical protein	A0A1S6KZX8	Salmonella_phage	9.4e-12	36.6
WP_046350632.1\|2749514_2749976_+\|tail	phage tail protein	A0A077K8R3	Ralstonia_phage	6.5e-37	52.5
WP_046350631.1\|2749972_2750425_+	phage virion morphogenesis protein	E5E3R3	Burkholderia_phage	9.8e-30	50.0
WP_046350630.1\|2750490_2751168_+\|plate	phage baseplate assembly protein V	F1BUP5	Erwinia_phage	2.3e-35	56.4
WP_046350629.1\|2751167_2751518_+	hypothetical protein	A4PE42	Ralstonia_virus	1.0e-26	52.6
WP_046350628.1\|2751521_2752421_+\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	8.1e-92	60.2
WP_046350627.1\|2752413_2752962_+\|tail	phage tail protein I	E5G6N9	Salmonella_phage	4.2e-51	51.9
WP_062654894.1\|2752958_2755016_+	hypothetical protein	M1TAS6	Escherichia_phage	6.7e-41	25.9
WP_052746598.1\|2755020_2755554_+	hypothetical protein	NA	NA	NA	NA
WP_046352106.1\|2755645_2756818_+\|tail	phage tail sheath protein	E5E3Q3	Burkholderia_phage	4.1e-144	64.5
WP_046352054.1\|2756833_2757343_+\|tail	phage major tail tube protein	E5FFG8	Burkholderia_phage	2.4e-56	62.1
WP_046352055.1\|2757363_2757669_+\|tail	phage tail assembly protein	E5E3Q1	Burkholderia_phage	6.0e-23	60.0
WP_082752769.1\|2757677_2757800_+\|tail	GpE family phage tail protein	E5E3Q0	Burkholderia_phage	3.1e-07	70.6
WP_046352056.1\|2757796_2758510_+	site-specific DNA-methyltransferase	V9IQV5	Stenotrophomonas_phage	2.2e-84	61.0
WP_046352057.1\|2758509_2761092_+\|tail	phage tail tape measure protein	A0A2H4JE61	uncultured_Caudovirales_phage	6.8e-184	45.9
WP_046352058.1\|2761091_2761502_+	hypothetical protein	A4PE53	Ralstonia_virus	1.2e-31	51.5
WP_046352059.1\|2761498_2762554_+	phage late control D family protein	E5E3P7	Burkholderia_phage	6.1e-107	58.9
WP_046352060.1\|2762573_2763929_-	hypothetical protein	NA	NA	NA	NA
WP_046352061.1\|2764140_2764431_+	hypothetical protein	NA	NA	NA	NA
WP_046352062.1\|2764427_2764778_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_046352063.1\|2764837_2765092_-	hypothetical protein	NA	NA	NA	NA
WP_052746599.1\|2765219_2765696_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_156455195.1\|2765782_2766019_+	hypothetical protein	NA	NA	NA	NA
WP_046352065.1\|2766461_2766920_+	hypothetical protein	NA	NA	NA	NA
WP_052746600.1\|2766916_2768827_+	hypothetical protein	Q1I108	Pasteurella_virus	1.8e-40	32.2
WP_046352066.1\|2768914_2769154_+	hypothetical protein	NA	NA	NA	NA
WP_046352067.1\|2769528_2770683_+\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	3.8e-118	56.6
WP_046352068.1\|2770782_2771118_-	hypothetical protein	NA	NA	NA	NA
WP_082752770.1\|2771701_2773450_-	DUF3365 domain-containing protein	NA	NA	NA	NA
WP_046352069.1\|2774280_2775420_+	RNA ligase RtcB family protein	A0A0K2CNT0	Brevibacillus_phage	1.2e-20	24.1
WP_046352070.1\|2775416_2776037_+	peptide chain release factor H	NA	NA	NA	NA
WP_046352071.1\|2776080_2776407_+	phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_046352072.1\|2776522_2777536_-	RNA 3'-terminal phosphate cyclase	NA	NA	NA	NA
WP_046352073.1\|2777553_2778357_-	nucleotidyltransferase domain-containing protein	A0A2D1GQQ2	Pseudomonas_phage	2.3e-45	42.9
WP_046352074.1\|2778369_2779590_-	RtcB family protein	K4JX39	Caulobacter_virus	4.7e-135	63.0
WP_046352075.1\|2779884_2781483_+	AAA family ATPase	NA	NA	NA	NA
WP_046352076.1\|2781665_2782832_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_046352077.1\|2783189_2783927_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_156455196.1\|2784369_2785056_-	hypothetical protein	NA	NA	NA	NA
WP_156455197.1\|2785045_2785276_+	hypothetical protein	NA	NA	NA	NA
WP_046352079.1\|2785289_2786063_-	hypothetical protein	NA	NA	NA	NA
WP_046352080.1\|2786396_2787155_+	hypothetical protein	NA	NA	NA	NA
WP_046352081.1\|2787814_2788801_+	hypothetical protein	NA	NA	NA	NA
WP_046352082.1\|2789099_2789564_+	hypothetical protein	NA	NA	NA	NA
WP_046352083.1\|2789691_2790012_+	hypothetical protein	NA	NA	NA	NA
WP_082752771.1\|2790079_2790772_+	DUF4365 domain-containing protein	NA	NA	NA	NA
WP_052746601.1\|2790872_2791469_+	hypothetical protein	NA	NA	NA	NA
WP_046352085.1\|2791582_2792458_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_046352086.1\|2792966_2793596_+	hypothetical protein	NA	NA	NA	NA
WP_046352087.1\|2793872_2794301_+	hypothetical protein	NA	NA	NA	NA
WP_046352088.1\|2794375_2794795_+	hypothetical protein	NA	NA	NA	NA
WP_046352089.1\|2794873_2795152_+	hypothetical protein	NA	NA	NA	NA
WP_046352090.1\|2795453_2795816_-	hypothetical protein	NA	NA	NA	NA
WP_046352091.1\|2795812_2796355_-	hypothetical protein	NA	NA	NA	NA
WP_082752772.1\|2796364_2796997_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_046352092.1\|2797253_2798276_-\|portal	phage portal protein	A4PE27	Ralstonia_virus	1.7e-125	65.6
WP_046352093.1\|2798276_2800028_-\|terminase	terminase ATPase subunit family protein	E5FFI8	Burkholderia_phage	6.3e-234	67.8
WP_046352095.1\|2801032_2802124_+\|capsid	phage major capsid protein, P2 family	K4NZP8	Burkholderia_phage	4.0e-101	54.0
WP_046352112.1\|2802150_2802780_+	hypothetical protein	A0A077K804	Ralstonia_phage	2.7e-49	48.2
WP_046352096.1\|2802883_2803351_+\|head	head completion/stabilization protein	E5E3S2	Burkholderia_phage	9.5e-36	53.8
WP_046352097.1\|2803350_2803557_+	hypothetical protein	A0A077K8R0	Ralstonia_phage	3.1e-15	57.4
WP_046352098.1\|2803561_2803930_+	hypothetical protein	A0A1S5NRL1	Burkholderia_phage	1.1e-18	44.9
WP_082752773.1\|2803926_2804412_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_082752921.1\|2804263_2804692_+	hypothetical protein	C7BGD8	Burkholderia_phage	2.9e-23	46.9
WP_052746604.1\|2804688_2805147_+	hypothetical protein	E5G6N2	Salmonella_phage	2.2e-13	37.5
WP_046352100.1\|2805687_2806140_+	phage virion morphogenesis protein	E5E3R3	Burkholderia_phage	5.8e-30	50.0
WP_046352101.1\|2806205_2806883_+\|plate	phage baseplate assembly protein V	F1BUP5	Erwinia_phage	1.3e-33	52.6
WP_046352102.1\|2806882_2807233_+	hypothetical protein	A4PE42	Ralstonia_virus	1.2e-27	53.4
WP_046352103.1\|2807236_2808136_+\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	2.3e-91	59.2
WP_046352104.1\|2808128_2808677_+\|tail	phage tail protein I	A0A2H4JAU2	uncultured_Caudovirales_phage	7.2e-51	52.3
WP_062654906.1\|2808673_2811418_+	hypothetical protein	F1BUP1	Erwinia_phage	1.6e-34	45.8
WP_052746614.1\|2811422_2811974_+	hypothetical protein	NA	NA	NA	NA
WP_046352578.1\|2812064_2813237_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	4.5e-143	63.0
WP_046352209.1\|2813252_2813762_+\|tail	phage major tail tube protein	A0A1S5NNH7	Burkholderia_phage	1.5e-55	62.1
WP_046352210.1\|2813780_2814074_+\|tail	phage tail assembly protein	E5E3Q1	Burkholderia_phage	2.9e-22	62.1
WP_082752774.1\|2814082_2814199_+\|tail	GpE family phage tail protein	E5E3Q0	Burkholderia_phage	4.3e-06	67.6
WP_046352211.1\|2814202_2814916_+	site-specific DNA-methyltransferase	V9IQV5	Stenotrophomonas_phage	4.2e-83	60.6
WP_046352212.1\|2814915_2817504_+\|tail	phage tail tape measure protein	A0A2H4JE61	uncultured_Caudovirales_phage	6.4e-190	46.8
WP_046352213.1\|2817503_2817914_+	hypothetical protein	A4PE53	Ralstonia_virus	1.6e-31	50.8
WP_046352214.1\|2817910_2818966_+	phage late control D family protein	E5E3P7	Burkholderia_phage	6.5e-109	60.2
WP_046352215.1\|2819033_2819258_+	TraY domain-containing protein	NA	NA	NA	NA
WP_046352216.1\|2819241_2819511_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2P1N333	Gordonia_phage	6.5e-05	35.3
WP_082752775.1\|2819917_2820370_-	helix-turn-helix transcriptional regulator	A4JWN8	Burkholderia_virus	1.0e-10	34.3
WP_046352217.1\|2820411_2820693_+	hypothetical protein	NA	NA	NA	NA
WP_156455198.1\|2820803_2821061_+	hypothetical protein	NA	NA	NA	NA
WP_046352219.1\|2821142_2821604_+	hypothetical protein	NA	NA	NA	NA
WP_052746616.1\|2821600_2823508_+	hypothetical protein	Q6K1F3	Salmonella_virus	4.6e-44	37.1
WP_046352220.1\|2823589_2823829_+	hypothetical protein	NA	NA	NA	NA
WP_082752776.1\|2823941_2824220_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_052746617.1\|2824219_2825362_+\|integrase	tyrosine-type recombinase/integrase	Q6JIJ8	Burkholderia_virus	7.0e-48	35.1
WP_082752777.1\|2825915_2827280_-	hypothetical protein	A0A0E3JI95	Rhodoferax_phage	5.1e-29	42.9
WP_082752778.1\|2827264_2827621_-	hypothetical protein	NA	NA	NA	NA
WP_046352224.1\|2827613_2828510_-	hypothetical protein	NA	NA	NA	NA
WP_082752779.1\|2828502_2829132_-	dTMP kinase	A0A191SB49	Nostoc_phage	8.1e-06	28.7
WP_046352226.1\|2829144_2829966_-	metallophosphoesterase	NA	NA	NA	NA
WP_046352227.1\|2830310_2831552_-	Fic family protein	NA	NA	NA	NA
WP_046352228.1\|2831730_2832531_-	DNA adenine methylase	Q5ZQW7	Pseudomonas_phage	2.2e-101	64.2
WP_082752780.1\|2832493_2832688_-	Com family DNA-binding transcriptional regulator	Q5ZQW8	Pseudomonas_phage	1.7e-07	58.7
WP_082752781.1\|2833058_2833502_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.9e-22	48.7
WP_046352229.1\|2833501_2834773_+	Y-family DNA polymerase	I6RSM4	Salmonella_phage	3.9e-84	42.2
WP_046352230.1\|2834769_2835105_-	hypothetical protein	NA	NA	NA	NA
WP_046352231.1\|2835179_2836286_-	hypothetical protein	NA	NA	NA	NA
WP_156455199.1\|2836385_2837507_-	hypothetical protein	NA	NA	NA	NA
WP_046352233.1\|2837518_2840383_-	hypothetical protein	NA	NA	NA	NA
WP_046352234.1\|2840379_2841375_-	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_046352235.1\|2841392_2844038_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_156455200.1\|2844228_2844402_-	hypothetical protein	NA	NA	NA	NA
WP_046352236.1\|2844328_2844688_-	hypothetical protein	A0A1Y0SUD7	Pseudomonas_phage	4.2e-07	34.8
WP_046352583.1\|2844684_2845149_-	lysozyme	A0A2H4J3P8	uncultured_Caudovirales_phage	3.3e-33	52.3
WP_046352237.1\|2845141_2845345_-	hypothetical protein	NA	NA	NA	NA
WP_046352238.1\|2845425_2846490_-	hypothetical protein	A0A2H4JBF6	uncultured_Caudovirales_phage	1.3e-72	45.1
WP_046352239.1\|2846493_2846700_-\|tail	phage tail protein	A0A2H4J9Z9	uncultured_Caudovirales_phage	5.8e-14	55.2
WP_052746619.1\|2846674_2847505_-\|tail	phage tail protein	A0A2H4J875	uncultured_Caudovirales_phage	1.3e-24	49.2
WP_046352240.1\|2847507_2850966_-	hypothetical protein	A0A2H4JG00	uncultured_Caudovirales_phage	9.1e-83	38.3
2849442:2849458	attL	NA	NA	NA	NA
WP_046352241.1\|2851110_2851368_-\|tail	phage tail assembly protein	A0A088FQX2	Escherichia_phage	3.4e-11	50.7
WP_046352242.1\|2851409_2851913_-\|tail	phage major tail tube protein	Q7M2A5	Pseudomonas_phage	1.1e-50	61.3
WP_046352243.1\|2851925_2853101_-\|tail	phage tail sheath family protein	A0A2H4J869	uncultured_Caudovirales_phage	2.0e-143	68.1
WP_046352244.1\|2853178_2854531_-	hypothetical protein	A0A2I7QLN8	Vibrio_phage	5.6e-28	34.5
WP_052746620.1\|2854540_2855038_-	hypothetical protein	NA	NA	NA	NA
WP_052746621.1\|2855034_2855664_-\|tail	phage tail protein I	D5LGZ2	Escherichia_phage	2.4e-18	37.4
WP_046352245.1\|2855660_2856626_-\|tail	tail fiber protein	V9IQV9	Stenotrophomonas_phage	1.7e-55	40.2
WP_046352246.1\|2856622_2856949_-\|plate	phage baseplate protein	A0A2H4JA09	uncultured_Caudovirales_phage	2.1e-26	54.6
WP_046352247.1\|2856953_2857157_-	hypothetical protein	NA	NA	NA	NA
WP_156455201.1\|2857314_2857983_+	hypothetical protein	NA	NA	NA	NA
WP_052746623.1\|2858022_2858640_-\|plate	phage baseplate assembly protein V	A0A2H4JG06	uncultured_Caudovirales_phage	4.0e-18	38.8
WP_052746624.1\|2858651_2859152_-	hypothetical protein	Q9JML9	Wolbachia_phage	1.4e-21	40.7
WP_052746625.1\|2859151_2859703_-	hypothetical protein	NA	NA	NA	NA
WP_046352248.1\|2859695_2859995_-	hypothetical protein	A0A2H4J879	uncultured_Caudovirales_phage	3.9e-19	49.0
WP_046352249.1\|2859998_2860994_-\|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	8.6e-111	59.2
WP_046352250.1\|2861059_2861407_-\|head	head decoration protein	NA	NA	NA	NA
WP_082752782.1\|2861403_2862597_-\|protease	Clp protease ClpP	A0A2H4JDI2	uncultured_Caudovirales_phage	8.8e-70	43.2
WP_046352252.1\|2862535_2864005_-\|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	4.9e-163	60.5
WP_046352253.1\|2864004_2864214_-	hypothetical protein	A0A2H4JA19	uncultured_Caudovirales_phage	8.9e-10	46.4
WP_046352254.1\|2864215_2866165_-\|terminase	phage terminase large subunit family protein	A0A2H4J898	uncultured_Caudovirales_phage	2.5e-231	58.5
WP_046352255.1\|2866175_2866766_-	hypothetical protein	NA	NA	NA	NA
WP_046352256.1\|2867102_2868404_-	FRG domain-containing protein	NA	NA	NA	NA
WP_046352257.1\|2868813_2869305_-	hypothetical protein	NA	NA	NA	NA
WP_046352258.1\|2869375_2869963_-	hypothetical protein	NA	NA	NA	NA
WP_046352259.1\|2869964_2870780_-	hypothetical protein	NA	NA	NA	NA
WP_046352260.1\|2870739_2871684_-	hypothetical protein	NA	NA	NA	NA
WP_046352261.1\|2871680_2872157_-	hypothetical protein	NA	NA	NA	NA
WP_046352591.1\|2872336_2872633_-	hypothetical protein	NA	NA	NA	NA
WP_156455202.1\|2872721_2873417_+	helix-turn-helix transcriptional regulator	A0A0R6PIF7	Moraxella_phage	9.5e-24	34.1
WP_156455203.1\|2873638_2873785_+	hypothetical protein	NA	NA	NA	NA
WP_156455204.1\|2873825_2874158_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_046352263.1\|2874037_2875051_+\|integrase	site-specific integrase	Q7Y5X7	Haemophilus_phage	5.2e-79	46.7
WP_046352264.1\|2875070_2876018_-	hypothetical protein	NA	NA	NA	NA
WP_046352265.1\|2876267_2876633_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_046352592.1\|2876598_2876916_-	integration host factor subunit alpha	A0A1P8CWT5	Bacillus_phage	1.7e-12	39.6
WP_046352266.1\|2876945_2879300_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_046352267.1\|2879403_2880390_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	2.6e-35	37.2
2879817:2879833	attR	NA	NA	NA	NA
WP_046352268.1\|2880529_2880889_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_046352269.1\|2880905_2881103_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_046352270.1\|2881272_2881818_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	2.5e-11	30.9
WP_046352271.1\|2881848_2883753_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	4.9e-131	38.1

DBSCAN-SWA_5

3090298 : 3099398

Bacillus_virus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052746644.1\|3090298_3092908_-	EAL domain-containing protein	G3MA91	Bacillus_virus	3.7e-20	33.3
WP_046352421.1\|3093026_3095333_-	type I DNA topoisomerase	A0A0G2YA05	Acanthamoeba_polyphaga_mimivirus	2.3e-98	36.5
WP_046352422.1\|3095595_3096672_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	4.6e-25	31.4
WP_046352423.1\|3096671_3097727_-	LysM peptidoglycan-binding domain-containing protein	G3MBQ1	Bacillus_virus	3.1e-10	34.0
WP_046352424.1\|3097875_3098379_+	peptide deformylase	E3SLL2	Synechococcus_phage	8.1e-17	40.5
WP_046352425.1\|3098471_3099398_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	3.7e-07	35.9

DBSCAN-SWA_6

3400669 : 3407775

Lake_Baikal_phage(28.57%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046351603.1\|3400669_3401893_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.1e-09	61.1
WP_046351602.1\|3402024_3402228_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.8e-20	71.2
WP_046351601.1\|3402342_3402546_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.1e-20	72.7
WP_046351600.1\|3402854_3403166_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-10	38.8
WP_046351599.1\|3403162_3405427_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	7.8e-168	41.8
WP_046351598.1\|3405487_3406312_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_046351597.1\|3406375_3407293_-	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	2.0e-29	29.0
WP_046351596.1\|3407289_3407775_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	2.6e-12	38.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP014222

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection