CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP011019	Escherichia coli strain CI5 plasmid unnamed, complete sequence	0 crisprs	RT,WYL,cas14j	0	0	1	0
NZ_CP011018	Escherichia coli strain CI5 chromosome, complete genome	7 crisprs	DEDDh,PD-DExK,DinG,c2c9_V-U4,cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	0	27	11	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

162966 : 198615

Enterobacteria_phage(21.43%)

transposase,protease,integrase

attL 152399:152412|attR 199075:199088

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
152399:152412	attL	NA	NA	NA	NA
WP_089557530.1\|162966_164190_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_032325769.1\|165173_166172_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_000587689.1\|167559_168186_+	ParA family plasmid-partitioning AAA ATPase	E5FFJ3	Burkholderia_phage	2.0e-17	31.1
WP_005015281.1\|168305_168485_+	hypothetical protein	NA	NA	NA	NA
WP_046201804.1\|170397_171054_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_046201805.1\|171104_171869_-	gluconate 5-dehydrogenase	F2NZ40	Diadromus_pulchellus_ascovirus	2.0e-14	27.4
WP_046201806.1\|171892_172357_-	YhcH/YjgK/YiaL family protein	NA	NA	NA	NA
WP_046201807.1\|172368_173304_-	sugar kinase	NA	NA	NA	NA
WP_046201808.1\|173300_174272_-	C-terminal binding protein	M1I4S0	Paramecium_bursaria_Chlorella_virus	1.6e-29	32.3
WP_046201809.1\|174564_175839_+	MFS transporter	NA	NA	NA	NA
WP_001398199.1\|176356_176758_-	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_000557619.1\|176690_176948_-	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_046201810.1\|177040_177694_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_046201811.1\|178270_182200_-	autotransporter outer membrane beta-barrel domain-containing protein	Q9LA54	Enterobacteria_phage	3.2e-217	37.1
WP_046201812.1\|182743_183142_-	hypothetical protein	NA	NA	NA	NA
WP_052734131.1\|183153_183507_-	hypothetical protein	NA	NA	NA	NA
WP_046201814.1\|183876_184296_-	Exc2 family lipoprotein	NA	NA	NA	NA
WP_000993925.1\|185326_185977_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.0e-16	43.6
WP_000623562.1\|185976_186324_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	4.4e-46	75.7
WP_046201816.1\|186343_187915_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.1e-168	58.9
WP_046201817.1\|188045_188468_-	DUF1380 family protein	NA	NA	NA	NA
WP_139108889.1\|188514_188817_-	antirestriction protein	NA	NA	NA	NA
WP_046201818.1\|190003_191173_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	1.3e-177	84.6
WP_072134512.1\|191176_191386_+	DUF4113 domain-containing protein	A0A1W6JNT0	Morganella_phage	2.5e-12	53.4
WP_046201819.1\|191526_192489_-	ParB/RepB/Spo0J family partition protein	Q1MVJ4	Enterobacteria_phage	8.0e-114	68.6
WP_000817642.1\|192485_193691_-	ParA family protein	Q1MVJ3	Enterobacteria_phage	5.6e-205	89.4
WP_000402944.1\|194064_194277_+	hypothetical protein	NA	NA	NA	NA
WP_001132895.1\|194449_194701_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_001270421.1\|194697_194985_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	5.8e-20	48.4
WP_046201820.1\|195270_195561_+	hypothetical protein	NA	NA	NA	NA
WP_000361612.1\|196618_197596_+	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	3.9e-100	59.2
WP_046201823.1\|197874_198615_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	3.5e-24	56.6
199075:199088	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP011018

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011018_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011018_1

726418-726541

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011018_1

>merge|NZ_CP011018|1|726418-726541|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP011018|1|1|726418-726541|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011018.1\|WP_001297805.1\|721267_721906_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP011018.1\|WP_001182365.1\|731860_733072_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP011018.1\|WP_000534291.1\|726855_728112_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP011018.1\|WP_001310861.1\|721969_722638_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP011018.1\|WP_000007283.1\|737007_737589_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP011018.1\|WP_001174942.1\|728152_729526_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NZ_CP011018.1\|WP_001069997.1\|722634_723420_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NZ_CP011018.1\|WP_001295403.1\|715871_717284_-\|pyruvate-kinase-PykF	unknown	unknown	gnl\|CDD\|181699
NZ_CP011018.1\|WP_000190982.1\|734113_735139_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP011018.1\|WP_000269501.1\|733184_734117_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP011018.1\|WP_000493947.1\|729740_730382_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP011018.1\|WP_000098911.1\|730421_731570_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP011018.1\|WP_001070230.1\|718505_719132_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP011018.1\|WP_000102278.1\|735437_735527_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP011018.1\|WP_000212657.1\|725977_726283_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP011018.1\|WP_000716922.1\|724247_725852_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP011018.1\|WP_001273528.1\|719152_721255_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NZ_CP011018.1\|WP_000701040.1\|735692_736862_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP011018.1\|WP_000528342.1\|717840_718050_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NZ_CP011018.1\|WP_000587560.1\|723423_724236_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159

Protein	Function_ID	Function_description	E-value
NZ_CP011018.1\|WP_001297805.1\|721267_721906_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	1.93584e-120
NZ_CP011018.1\|WP_001182365.1\|731860_733072_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP011018.1\|WP_000534291.1\|726855_728112_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP011018.1\|WP_001310861.1\|721969_722638_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	2.09652e-76
NZ_CP011018.1\|WP_000007283.1\|737007_737589_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP011018.1\|WP_001174942.1\|728152_729526_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP011018.1\|WP_001069997.1\|722634_723420_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.33298e-163
NZ_CP011018.1\|WP_001295403.1\|715871_717284_-\|pyruvate-kinase-PykF	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP011018.1\|WP_000190982.1\|734113_735139_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP011018.1\|WP_000269501.1\|733184_734117_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP011018.1\|WP_000493947.1\|729740_730382_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NZ_CP011018.1\|WP_000098911.1\|730421_731570_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP011018.1\|WP_001070230.1\|718505_719132_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NZ_CP011018.1\|WP_000212657.1\|725977_726283_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
NZ_CP011018.1\|WP_000716922.1\|724247_725852_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP011018.1\|WP_001273528.1\|719152_721255_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NZ_CP011018.1\|WP_000701040.1\|735692_736862_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
NZ_CP011018.1\|WP_000528342.1\|717840_718050_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NZ_CP011018.1\|WP_000587560.1\|723423_724236_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	8.20825e-175

>NZ_CP011018.1|WP_000212657.1|725977_726283_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP011018.1|WP_000716922.1|724247_725852_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP011018.1|WP_000587560.1|723423_724236_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC
>NZ_CP011018.1|WP_001069997.1|722634_723420_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP011018.1|WP_001310861.1|721969_722638_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP011018.1|WP_001297805.1|721267_721906_+|YdhW-family-putative-oxidoreductase-system-protein
MNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP011018.1|WP_001273528.1|719152_721255_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>NZ_CP011018.1|WP_001070230.1|718505_719132_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP011018.1|WP_000528342.1|717840_718050_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP011018.1|WP_001295403.1|715871_717284_-|pyruvate-kinase-PykF
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP011018.1|WP_000534291.1|726855_728112_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDGVTFIVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP011018.1|WP_001174942.1|728152_729526_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR
>NZ_CP011018.1|WP_000493947.1|729740_730382_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NZ_CP011018.1|WP_000098911.1|730421_731570_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP011018.1|WP_001182365.1|731860_733072_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVTLGYMMQRCEEVGCQNHGNAEVAHSESH
>NZ_CP011018.1|WP_000269501.1|733184_734117_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP011018.1|WP_000190982.1|734113_735139_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP011018.1|WP_000102278.1|735437_735527_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP011018.1|WP_000701040.1|735692_736862_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP011018.1|WP_000007283.1|737007_737589_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Crispr_ID: NZ_CP011018_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011018_2

1438579-1438670

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011018_2

>merge|NZ_CP011018|2|1438579-1438670|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP011018|2|2|1438579-1438670|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011018.1\|WP_001230242.1\|1447486_1448659_-\|pentaheme-c-type-cytochrome-TorC	unknown	unknown	gnl\|CDD\|184992
NZ_CP011018.1\|WP_001352489.1\|1432846_1433938_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP011018.1\|WP_000979516.1\|1427654_1427864_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011018.1\|WP_001143120.1\|1439710_1439938_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182285
NZ_CP011018.1\|WP_024251424.1\|1436961_1438290_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP011018.1\|WP_001384404.1\|1435035_1435836_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP011018.1\|WP_001307100.1\|1433937_1434630_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NZ_CP011018.1\|WP_000191701.1\|1431920_1432559_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP011018.1\|WP_001299828.1\|1427918_1431881_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP011018.1\|WP_001044280.1\|1439975_1441217_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	unknown	unknown	gnl\|CDD\|182284
NZ_CP011018.1\|WP_001001171.1\|1435845_1436436_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP011018.1\|WP_001151437.1\|1439093_1439690_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NZ_CP011018.1\|WP_000420617.1\|1443026_1443947_+\|curved-DNA-binding-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP011018.1\|WP_000024560.1\|1443946_1444252_+\|chaperone-modulator-CbpM	unknown	unknown	gnl\|CDD\|182346
NZ_CP011018.1\|WP_001062106.1\|1444940_1447487_-\|trimethylamine-N-oxide-reductase-TorA	unknown	unknown	gnl\|CDD\|237909
NZ_CP011018.1\|WP_000209866.1\|1444344_1444944_-\|molecular-chaperone-TorD	unknown	unknown	gnl\|CDD\|235326
NZ_CP011018.1\|WP_000535358.1\|1441875_1442766_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182074
NZ_CP011018.1\|WP_001028096.1\|1436446_1436941_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654
NZ_CP011018.1\|WP_001126780.1\|1434641_1435028_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NZ_CP011018.1\|WP_000787869.1\|1441509_1441758_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182074

Protein	Function_ID	Function_description	E-value
NZ_CP011018.1\|WP_001230242.1\|1447486_1448659_-\|pentaheme-c-type-cytochrome-TorC	gnl\|CDD\|184992	PRK15032, PRK15032, pentaheme c-type cytochrome TorC.	0
NZ_CP011018.1\|WP_001352489.1\|1432846_1433938_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP011018.1\|WP_001143120.1\|1439710_1439938_+\|hypothetical-protein	gnl\|CDD\|182285	PRK10174, PRK10174, hypothetical protein; Provisional.	8.66725e-44
NZ_CP011018.1\|WP_024251424.1\|1436961_1438290_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP011018.1\|WP_001384404.1\|1435035_1435836_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	8.05337e-142
NZ_CP011018.1\|WP_001307100.1\|1433937_1434630_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	2.45431e-169
NZ_CP011018.1\|WP_000191701.1\|1431920_1432559_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	1.3356e-153
NZ_CP011018.1\|WP_001299828.1\|1427918_1431881_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP011018.1\|WP_001044280.1\|1439975_1441217_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	gnl\|CDD\|182284	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional.	0
NZ_CP011018.1\|WP_001001171.1\|1435845_1436436_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	1.00331e-130
NZ_CP011018.1\|WP_001151437.1\|1439093_1439690_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	8.51484e-133
NZ_CP011018.1\|WP_000420617.1\|1443026_1443947_+\|curved-DNA-binding-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	0
NZ_CP011018.1\|WP_000024560.1\|1443946_1444252_+\|chaperone-modulator-CbpM	gnl\|CDD\|182346	PRK10265, PRK10265, chaperone modulator CbpM.	5.75956e-65
NZ_CP011018.1\|WP_001062106.1\|1444940_1447487_-\|trimethylamine-N-oxide-reductase-TorA	gnl\|CDD\|237909	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA.	0
NZ_CP011018.1\|WP_000209866.1\|1444344_1444944_-\|molecular-chaperone-TorD	gnl\|CDD\|235326	PRK04976, torD, chaperone protein TorD; Validated.	2.07423e-84
NZ_CP011018.1\|WP_000535358.1\|1441875_1442766_-\|hypothetical-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	0
NZ_CP011018.1\|WP_001028096.1\|1436446_1436941_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	8.28716e-106
NZ_CP011018.1\|WP_001126780.1\|1434641_1435028_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	5.99808e-85
NZ_CP011018.1\|WP_000787869.1\|1441509_1441758_-\|hypothetical-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	4.88813e-50

>NZ_CP011018.1|WP_024251424.1|1436961_1438290_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNLLGLGKAVDFTLVSHAAWFGLPHFSTPAFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVIHQEP
>NZ_CP011018.1|WP_001028096.1|1436446_1436941_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
>NZ_CP011018.1|WP_001001171.1|1435845_1436436_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
>NZ_CP011018.1|WP_001384404.1|1435035_1435836_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARVPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP011018.1|WP_001126780.1|1434641_1435028_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP011018.1|WP_001307100.1|1433937_1434630_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFAHIA
>NZ_CP011018.1|WP_001352489.1|1432846_1433938_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAVRMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NZ_CP011018.1|WP_000191701.1|1431920_1432559_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
>NZ_CP011018.1|WP_001299828.1|1427918_1431881_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP011018.1|WP_000979516.1|1427654_1427864_-|hypothetical-protein
MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>NZ_CP011018.1|WP_001151437.1|1439093_1439690_+|NAD(P)H:quinone-oxidoreductase
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>NZ_CP011018.1|WP_001143120.1|1439710_1439938_+|hypothetical-protein
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>NZ_CP011018.1|WP_001044280.1|1439975_1441217_-|bifunctional-glucose-1-phosphatase/inositol-phosphatase
MNKTLIAAAVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECPPPYTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAFSEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNERTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDANGFCPMDKFDSVLNEAVK
>NZ_CP011018.1|WP_000787869.1|1441509_1441758_-|hypothetical-protein
MKNFLTALSDSICSLFIVNSNVASISLGNESFSTDEDLEYGYLINTGNHYDVYLPPELFAQAYKLKNKEMNAQLDYLNRYAI
>NZ_CP011018.1|WP_000535358.1|1441875_1442766_-|hypothetical-protein
MGSNIHGISCTANNYLKQAWNDIKNEYEKNQTYSITLFENTLVCFMRLYNELRRKVNEEDTPCLECESLEKEFEEMQNDNDLSLFMRTLRTNDTQIYSGVSGGITYTIQYVQNVDIVRVSLPGRGSESITDFKGYYWYGFMEYIENITACDDVFSEYCLDDENMSIQPEQINTPGISDLDSGIDLSGISFIQSEINKTYGLKYAPVDGDGYCLLRAILVLKEHEYSWALGSHKTQKQVYEEFIKIVDKQTIEALVDTAFYNLREDVKTLFGVDLQSDNKIQGEGSLMSWNFLFFKK
>NZ_CP011018.1|WP_000420617.1|1443026_1443947_+|curved-DNA-binding-protein
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPAARGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>NZ_CP011018.1|WP_000024560.1|1443946_1444252_+|chaperone-modulator-CbpM
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
>NZ_CP011018.1|WP_000209866.1|1444344_1444944_-|molecular-chaperone-TorD
MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNELENCIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFAARCHQYDSFGFYAALSQLLLVLVECDHQNR
>NZ_CP011018.1|WP_001062106.1|1444940_1447487_-|trimethylamine-N-oxide-reductase-TorA
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYGKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEYVPASQVKS
>NZ_CP011018.1|WP_001230242.1|1447486_1448659_-|pentaheme-c-type-cytochrome-TorC
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK

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Crispr_ID: NZ_CP011018_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011018_3

1580589-1580737

Orphan

I-F

Consensus_repeat	Method
ATTTCTAAGCTGCCTGTACGGCAGTGAAC	CRISPRCasFinder
ATTTCTAAGCTGTCTGTACGGCAGTGAAC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP011018_3

>merge|NZ_CP011018|3|1580589-1580737|CRISPRCasFinder,PILER-CR
GCATTTTATCTGTCTGTACGGCAGTGAACATGGTGGGCGGGTGGAGTATGTTACCTGTGAATTTCTAAGCTGCCTGTACGGCAGTGAACGCGTTCGCAAAGGTTTTACCGCACCCCGTCGATTTCTAAGCTGTCTGTACGGCAGTGAAC

>NZ_CP011018|3|3|1580589-1580737|CRISPRCasFinder
GCATTTTATCTGTCTGTACGGCAGTGAAC	ATGGTGGGCGGGTGGAGTATGTTACCTGTGA
ATTTCTAAGCTGCCTGTACGGCAGTGAAC	GCGTTCGCAAAGGTTTTACCGCACCCCGTCG
ATTTCTAAGCTGTCTGTACGGCAGTGAAC

>NZ_CP011018|3|1|1580598-1580737|PILER-CR
CTGTCTGTACGGCAGTGAACATGGTGGGC	GGGTGGAGTATGTTACCTGTGAATTTCTAAG
CTGCCTGTACGGCAGTGAACGCGTTCGCA	AAGGTTTTACCGCACCCCGTCGATTTCTAAG
CTGTCTGTACGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011018.1\|WP_000410785.1\|1583900_1584125_+\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
NZ_CP011018.1\|WP_000188180.1\|1584197_1586144_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NZ_CP011018.1\|WP_000491127.1\|1591634_1592534_+\|L-lysine-exporter-LysO	unknown	unknown	gnl\|CDD\|225287
NZ_CP011018.1\|WP_001298299.1\|1590443_1591139_+\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NZ_CP011018.1\|WP_000886683.1\|1565419_1566712_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP011018.1\|WP_001040187.1\|1579809_1580028_+\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NZ_CP011018.1\|WP_000520781.1\|1583257_1583578_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP011018.1\|WP_032215246.1\|1586140_1587256_-\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NZ_CP011018.1\|WP_001295343.1\|1568156_1568768_-\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NZ_CP011018.1\|WP_001043587.1\|1575290_1577057_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NZ_CP011018.1\|WP_001355621.1\|1587406_1588363_+\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
NZ_CP011018.1\|WP_000537418.1\|1574202_1575168_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NZ_CP011018.1\|WP_001202188.1\|1577057_1578779_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
NZ_CP011018.1\|WP_001241678.1\|1578820_1579525_+\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NZ_CP011018.1\|WP_000458817.1\|1592677_1594330_+\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NZ_CP011018.1\|WP_000067755.1\|1566802_1568146_-\|replication-associated-recombination-protein-RarA	unknown	unknown	gnl\|CDD\|237355
NZ_CP011018.1\|WP_000599820.1\|1588359_1590018_-\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NZ_CP011018.1\|WP_000228473.1\|1573163_1573658_-\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009
NZ_CP011018.1\|WP_000934041.1\|1580950_1583227_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
NZ_CP011018.1\|WP_000077063.1\|1568922_1573029_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669

Protein	Function_ID	Function_description	E-value
NZ_CP011018.1\|WP_000410785.1\|1583900_1584125_+\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
NZ_CP011018.1\|WP_000188180.1\|1584197_1586144_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NZ_CP011018.1\|WP_000491127.1\|1591634_1592534_+\|L-lysine-exporter-LysO	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	4.62598e-118
NZ_CP011018.1\|WP_001298299.1\|1590443_1591139_+\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	2.04944e-144
NZ_CP011018.1\|WP_000886683.1\|1565419_1566712_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP011018.1\|WP_001040187.1\|1579809_1580028_+\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
NZ_CP011018.1\|WP_000520781.1\|1583257_1583578_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
NZ_CP011018.1\|WP_032215246.1\|1586140_1587256_-\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NZ_CP011018.1\|WP_001295343.1\|1568156_1568768_-\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
NZ_CP011018.1\|WP_001043587.1\|1575290_1577057_+\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP011018.1\|WP_001355621.1\|1587406_1588363_+\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	1.27645e-131
NZ_CP011018.1\|WP_000537418.1\|1574202_1575168_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NZ_CP011018.1\|WP_001202188.1\|1577057_1578779_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP011018.1\|WP_001241678.1\|1578820_1579525_+\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	3.45002e-139
NZ_CP011018.1\|WP_000458817.1\|1592677_1594330_+\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NZ_CP011018.1\|WP_000067755.1\|1566802_1568146_-\|replication-associated-recombination-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP011018.1\|WP_000599820.1\|1588359_1590018_-\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NZ_CP011018.1\|WP_000228473.1\|1573163_1573658_-\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
NZ_CP011018.1\|WP_000934041.1\|1580950_1583227_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NZ_CP011018.1\|WP_000077063.1\|1568922_1573029_-\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0

>NZ_CP011018.1|WP_001040187.1|1579809_1580028_+|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NZ_CP011018.1|WP_001241678.1|1578820_1579525_+|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
>NZ_CP011018.1|WP_001202188.1|1577057_1578779_+|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAESLRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>NZ_CP011018.1|WP_001043587.1|1575290_1577057_+|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQEEI
>NZ_CP011018.1|WP_000537418.1|1574202_1575168_+|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NZ_CP011018.1|WP_000228473.1|1573163_1573658_-|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NZ_CP011018.1|WP_000077063.1|1568922_1573029_-|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPSQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQSVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVPPQQQYQQPQQPVAPQPQYQQPQQQVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NZ_CP011018.1|WP_001295343.1|1568156_1568768_-|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>NZ_CP011018.1|WP_000067755.1|1566802_1568146_-|replication-associated-recombination-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NZ_CP011018.1|WP_000886683.1|1565419_1566712_-|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
>NZ_CP011018.1|WP_000934041.1|1580950_1583227_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>NZ_CP011018.1|WP_000520781.1|1583257_1583578_-|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NZ_CP011018.1|WP_000410785.1|1583900_1584125_+|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>NZ_CP011018.1|WP_000188180.1|1584197_1586144_-|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGITLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNVAGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>NZ_CP011018.1|WP_032215246.1|1586140_1587256_-|macrolide-transporter-subunit-MacA
MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTMIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>NZ_CP011018.1|WP_001355621.1|1587406_1588363_+|DUF535-domain-containing-protein
MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG
>NZ_CP011018.1|WP_000599820.1|1588359_1590018_-|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEECWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>NZ_CP011018.1|WP_001298299.1|1590443_1591139_+|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRD
>NZ_CP011018.1|WP_000491127.1|1591634_1592534_+|L-lysine-exporter-LysO
MFSGLLIILVPLIVGYLIPLRQKAALKVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>NZ_CP011018.1|WP_000458817.1|1592677_1594330_+|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA

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Crispr_ID: NZ_CP011018_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011018_4

2197536-2197683

Orphan

Consensus_repeat	Method
CGCGAGCGCCTTATCCGACCTACGGTTCAGACCTGTAGGCATGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011018_4

>merge|NZ_CP011018|4|2197536-2197683|CRISPRCasFinder
CGCGAGCGCCTTATCCGACCTACGGTTCAGACCTGTAGGCATGATAAGACGCGGTAAGCGTCGCATCAGGCATCGGCGCGGGGTGTCGGATGCGACGCGAGCGCCTTATCCGACCTACGGTTCAGGCCTGTAGGCATGATAAGACGCG

>NZ_CP011018|4|4|2197536-2197683|CRISPRCasFinder
CGCGAGCGCCTTATCCGACCTACGGTTCAGACCTGTAGGCATGATAAGACGCG	GTAAGCGTCGCATCAGGCATCGGCGCGGGGTGTCGGATGCGA
CGCGAGCGCCTTATCCGACCTACGGTTCAGGCCTGTAGGCATGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011018.1\|WP_001402057.1\|2203804_2205391_+\|propionate-catabolism-operon-regulatory-protein-PrpR	unknown	unknown	gnl\|CDD\|237963
NZ_CP011018.1\|WP_001542685.1\|2191097_2192279_-\|cyanate-transporter-CynX	unknown	unknown	gnl\|CDD\|236614
NZ_CP011018.1\|WP_000976975.1\|2205910_2206582_+\|LysE-family-transporter	unknown	unknown	gnl\|CDD\|273358
NZ_CP011018.1\|WP_032217651.1\|2185938_2189013_+\|beta-galactosidase	unknown	unknown	gnl\|CDD\|236548
NZ_CP011018.1\|WP_001285909.1\|2201159_2202329_-\|2-methylcitrate-synthase	unknown	unknown	gnl\|CDD\|183463
NZ_CP011018.1\|WP_001295686.1\|2194790_2196074_-\|cytosine/isoguanine-deaminase	unknown	unknown	gnl\|CDD\|181713
NZ_CP011018.1\|WP_000291549.1\|2189064_2190318_+\|lactose-permease	unknown	unknown	gnl\|CDD\|236549
NZ_CP011018.1\|WP_001335915.1\|2190383_2190995_+\|galactoside-O-acetyltransferase	unknown	unknown	gnl\|CDD\|181930
NZ_CP011018.1\|WP_001275873.1\|2199674_2201126_-\|2-methylcitrate-dehydratase	unknown	unknown	gnl\|CDD\|181845
NZ_CP011018.1\|WP_000691953.1\|2205488_2205764_-\|DUF1471-domain-containing-protein	unknown	unknown	gnl\|CDD\|182151
NZ_CP011018.1\|WP_000658652.1\|2192785_2193445_-\|carbonic-anhydrase-CynT	unknown	unknown	gnl\|CDD\|238449
NZ_CP011018.1\|WP_000805885.1\|2184733_2185816_+\|DNA-binding-transcriptional-repressor-LacI	unknown	unknown	gnl\|CDD\|181929
NZ_CP011018.1\|WP_001402056.1\|2207255_2208071_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011018.1\|WP_000076233.1\|2196063_2197323_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|236821
NZ_CP011018.1\|WP_000290616.1\|2206598_2206844_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011018.1\|WP_000052206.1\|2202675_2203566_-\|methylisocitrate-lyase	unknown	unknown	gnl\|CDD\|183086
NZ_CP011018.1\|WP_000010270.1\|2197748_2199635_-\|propionate--CoA-ligase	unknown	unknown	gnl\|CDD\|182517
NZ_CP011018.1\|WP_000616241.1\|2192284_2192755_-\|cyanase	unknown	unknown	gnl\|CDD\|224430
NZ_CP011018.1\|WP_000692754.1\|2208313_2209363_-\|NADPH-dependent-aldehyde-reductase-YahK	unknown	unknown	gnl\|CDD\|176186
NZ_CP011018.1\|WP_000952481.1\|2193554_2194454_+\|transcriptional-regulator-CynR	unknown	unknown	gnl\|CDD\|183051

Protein	Function_ID	Function_description	E-value
NZ_CP011018.1\|WP_001402057.1\|2203804_2205391_+\|propionate-catabolism-operon-regulatory-protein-PrpR	gnl\|CDD\|237963	PRK15424, PRK15424, propionate catabolism operon regulatory protein PrpR; Provisional.	0
NZ_CP011018.1\|WP_001542685.1\|2191097_2192279_-\|cyanate-transporter-CynX	gnl\|CDD\|236614	PRK09705, cynX, putative cyanate transporter; Provisional.	0
NZ_CP011018.1\|WP_000976975.1\|2205910_2206582_+\|LysE-family-transporter	gnl\|CDD\|273358	TIGR00949, Uncharacterized_membrane_protein_YahN, The Resistance to Homoserine/Threonine (RhtB) Family protein. [Transport and binding proteins, Amino acids, peptides and amines].	1.5842e-77
NZ_CP011018.1\|WP_032217651.1\|2185938_2189013_+\|beta-galactosidase	gnl\|CDD\|236548	PRK09525, lacZ, beta-galactosidase.	0
NZ_CP011018.1\|WP_001285909.1\|2201159_2202329_-\|2-methylcitrate-synthase	gnl\|CDD\|183463	PRK12351, PRK12351, methylcitrate synthase; Provisional.	0
NZ_CP011018.1\|WP_001295686.1\|2194790_2196074_-\|cytosine/isoguanine-deaminase	gnl\|CDD\|181713	PRK09230, PRK09230, cytosine deaminase; Provisional.	0
NZ_CP011018.1\|WP_000291549.1\|2189064_2190318_+\|lactose-permease	gnl\|CDD\|236549	PRK09528, lacY, galactoside permease; Reviewed.	0
NZ_CP011018.1\|WP_001335915.1\|2190383_2190995_+\|galactoside-O-acetyltransferase	gnl\|CDD\|181930	PRK09527, lacA, galactoside O-acetyltransferase; Reviewed.	2.21019e-143
NZ_CP011018.1\|WP_001275873.1\|2199674_2201126_-\|2-methylcitrate-dehydratase	gnl\|CDD\|181845	PRK09425, prpD, bifunctional 2-methylcitrate dehydratase/aconitate hydratase.	0
NZ_CP011018.1\|WP_000691953.1\|2205488_2205764_-\|DUF1471-domain-containing-protein	gnl\|CDD\|182151	PRK09929, PRK09929, hypothetical protein; Provisional.	2.40918e-43
NZ_CP011018.1\|WP_000658652.1\|2192785_2193445_-\|carbonic-anhydrase-CynT	gnl\|CDD\|238449	cd00884, beta_CA_cladeB, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	1.39049e-95
NZ_CP011018.1\|WP_000805885.1\|2184733_2185816_+\|DNA-binding-transcriptional-repressor-LacI	gnl\|CDD\|181929	PRK09526, lacI, lac repressor; Reviewed.	0
NZ_CP011018.1\|WP_000076233.1\|2196063_2197323_-\|cytosine-permease	gnl\|CDD\|236821	PRK11017, codB, cytosine permease; Provisional.	0
NZ_CP011018.1\|WP_000052206.1\|2202675_2203566_-\|methylisocitrate-lyase	gnl\|CDD\|183086	PRK11320, prpB, 2-methylisocitrate lyase; Provisional.	0
NZ_CP011018.1\|WP_000010270.1\|2197748_2199635_-\|propionate--CoA-ligase	gnl\|CDD\|182517	PRK10524, prpE, propionyl-CoA synthetase; Provisional.	0
NZ_CP011018.1\|WP_000616241.1\|2192284_2192755_-\|cyanase	gnl\|CDD\|224430	COG1513, CynS, Cyanate lyase [Inorganic ion transport and metabolism].	5.00357e-84
NZ_CP011018.1\|WP_000692754.1\|2208313_2209363_-\|NADPH-dependent-aldehyde-reductase-YahK	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP011018.1\|WP_000952481.1\|2193554_2194454_+\|transcriptional-regulator-CynR	gnl\|CDD\|183051	PRK11242, PRK11242, DNA-binding transcriptional regulator CynR; Provisional.	1.90845e-174

>NZ_CP011018.1|WP_000076233.1|2196063_2197323_-|cytosine-permease
MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLGTGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPAIACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFGRNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNIWTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPPVGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGALSYLILNPILNRKTTAAMTHVEANSVE
>NZ_CP011018.1|WP_001295686.1|2194790_2196074_-|cytosine/isoguanine-deaminase
MSNNALQTIINARLPGEEGLWQIHLQDGKISAIDAQSGVMPITENSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVKQRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGILSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQVPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR
>NZ_CP011018.1|WP_000952481.1|2193554_2194454_+|transcriptional-regulator-CynR
MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLGVPLFDRSGRTIRLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPGITLQLQEMSQEKIEDLLCRDELDVGIAFAPVHSPELEAIPLLTESLALVVAKHHPLAACEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVVIEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQTAAAKAFLHMALDKCAVVGGNESR
>NZ_CP011018.1|WP_000658652.1|2192785_2193445_-|carbonic-anhydrase-CynT
MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRLVPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCGAMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANLQTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTAA
>NZ_CP011018.1|WP_000616241.1|2192284_2192755_-|cyanase
MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
>NZ_CP011018.1|WP_001542685.1|2191097_2192279_-|cyanate-transporter-CynX
MRNHQKTFTMLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFSVAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSVLLLSSALLGGVGIGIIQAVMPSVIKRRFQQRTPLVMGLWSAALMGGGGLGAAITPWLVQHSETWYQTLAWWALPAVVALFAWWWQSAREVASSHKTTTTPVRVVFTPRAWTLGVYFGLINGGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLALVLQLVGFCGFIWLPLQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGKLVAFMQGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPVRFPQLWVKEA
>NZ_CP011018.1|WP_001335915.1|2190383_2190995_+|galactoside-O-acetyltransferase
MNMPMTERIRAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEVEKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGAGSIVTKDIPPNVVAAGVPCRVIREINDRDKHYYFKDYKVESSV
>NZ_CP011018.1|WP_000291549.1|2189064_2190318_+|lactose-permease
MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLRRQVNEVA
>NZ_CP011018.1|WP_032217651.1|2185938_2189013_+|beta-galactosidase
MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPAENPTGCYSLTFNIDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGKNRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPSTQISDFHVATHFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPALWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGELRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWLAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKYQQQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPGLPQPESAGQLWLTVHVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKVAGHYQAEAALLQCSADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
>NZ_CP011018.1|WP_000805885.1|2184733_2185816_+|DNA-binding-transcriptional-repressor-LacI
MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACANVPALFLDVSDQTPINSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRLESGQ
>NZ_CP011018.1|WP_000010270.1|2197748_2199635_-|propionate--CoA-ligase
MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFARWFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRSLGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIVSADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQHIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGVFFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAPTAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESGWPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGCIQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTREIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALVDSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQAMEE
>NZ_CP011018.1|WP_001275873.1|2199674_2201126_-|2-methylcitrate-dehydratase
MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDTLGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFNDTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTGMIKAHEIQGCIALENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTGTRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSYVMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDKKGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFTADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQFPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI
>NZ_CP011018.1|WP_001285909.1|2201159_2202329_-|2-methylcitrate-synthase
MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHYRGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPAASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERIQPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSDMYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPVYTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNMMGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ
>NZ_CP011018.1|WP_000052206.1|2202675_2203566_-|methylisocitrate-lyase
MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYLSGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVKSMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTDALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATPLFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYESINYYQYEEKLDNLFARSQVK
>NZ_CP011018.1|WP_001402057.1|2203804_2205391_+|propionate-catabolism-operon-regulatory-protein-PrpR
MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQLGFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGKLTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAGLITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDMLGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSHPFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLPLQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGRFRRDLFYRLSILRLQLPPLRERVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRELRNMMERLALFLSVEPTPDLTPQFMQLLLPELARESAKTPAPRLLTPQQALEKFNGDKTAAANYLGISRTTFWRRLKS
>NZ_CP011018.1|WP_000691953.1|2205488_2205764_-|DUF1471-domain-containing-protein
MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVESQYEKIGDISTSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK
>NZ_CP011018.1|WP_000976975.1|2205910_2206582_+|LysE-family-transporter
MMKLLHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQTSLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAWCSMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTWARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYEGVTQR
>NZ_CP011018.1|WP_000290616.1|2206598_2206844_-|hypothetical-protein
MAVQLFKTLLNQIPLLSSLQSGTLPLFGYSGWGRPMKKAHTGESGLKWEAKDSSKLIGNKDHALRGLSSPMAVIRQIRLIT
>NZ_CP011018.1|WP_001402056.1|2207255_2208071_-|hypothetical-protein
MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFKVLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWSDDNALTINVQFNDFPGFYDWMDYPDHPVKFVFRILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFIDSVRTDCKCILLEHHMPLLRIFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYPVFPESLVMLLLSVLDVKTYRDDARLNEWISNRVQELGDRYYPVNKHVKIRYTL
>NZ_CP011018.1|WP_000692754.1|2208313_2209363_-|NADPH-dependent-aldehyde-reductase-YahK
MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKSPEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRGDVKYRFVIDNRTLTD

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Crispr_ID: NZ_CP011018_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011018_5

3977000-3977117

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011018_5

>merge|NZ_CP011018|5|3977000-3977117|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

>NZ_CP011018|5|5|3977000-3977117|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	GTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011018.1\|WP_000096086.1\|3982020_3982320_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP011018.1\|WP_000107720.1\|3967302_3968634_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP011018.1\|WP_000719990.1\|3972209_3972599_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP011018.1\|WP_001297155.1\|3981442_3981925_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP011018.1\|WP_001297162.1\|3968659_3969868_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP011018.1\|WP_000861734.1\|3969901_3972196_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087
NZ_CP011018.1\|WP_000633577.1\|3977377_3978079_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP011018.1\|WP_000548347.1\|3966291_3967281_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NZ_CP011018.1\|WP_000460535.1\|3975668_3976979_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP011018.1\|WP_000531201.1\|3980386_3981373_-\|glutathionyl-hydroquinone-reductase-YqjG	unknown	unknown	gnl\|CDD\|223512
NZ_CP011018.1\|WP_001041010.1\|3978183_3979080_+\|DNA-binding-transcriptional-regulator-YhaJ	unknown	unknown	gnl\|CDD\|176122
NZ_CP011018.1\|WP_000401598.1\|3974309_3975641_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP011018.1\|WP_000785722.1\|3982309_3982714_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP011018.1\|WP_001295544.1\|3977190_3977355_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011018.1\|WP_000384145.1\|3979728_3980094_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP011018.1\|WP_000622115.1\|3972670_3974035_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP011018.1\|WP_000031415.1\|3982716_3983022_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP011018.1\|WP_000145820.1\|3964721_3965066_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP011018.1\|WP_000104211.1\|3965254_3966193_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP011018.1\|WP_001198780.1\|3979130_3979487_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694

Protein	Function_ID	Function_description	E-value
NZ_CP011018.1\|WP_000096086.1\|3982020_3982320_-\|hypothetical-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
NZ_CP011018.1\|WP_000107720.1\|3967302_3968634_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP011018.1\|WP_000719990.1\|3972209_3972599_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP011018.1\|WP_001297155.1\|3981442_3981925_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.8408e-29
NZ_CP011018.1\|WP_001297162.1\|3968659_3969868_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP011018.1\|WP_000861734.1\|3969901_3972196_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP011018.1\|WP_000633577.1\|3977377_3978079_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.02982e-67
NZ_CP011018.1\|WP_000548347.1\|3966291_3967281_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NZ_CP011018.1\|WP_000460535.1\|3975668_3976979_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0
NZ_CP011018.1\|WP_000531201.1\|3980386_3981373_-\|glutathionyl-hydroquinone-reductase-YqjG	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP011018.1\|WP_001041010.1\|3978183_3979080_+\|DNA-binding-transcriptional-regulator-YhaJ	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2986e-51
NZ_CP011018.1\|WP_000401598.1\|3974309_3975641_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	2.53913e-167
NZ_CP011018.1\|WP_000785722.1\|3982309_3982714_-\|hypothetical-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
NZ_CP011018.1\|WP_000384145.1\|3979728_3980094_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42
NZ_CP011018.1\|WP_000622115.1\|3972670_3974035_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
NZ_CP011018.1\|WP_000031415.1\|3982716_3983022_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
NZ_CP011018.1\|WP_000145820.1\|3964721_3965066_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	3.36123e-66
NZ_CP011018.1\|WP_000104211.1\|3965254_3966193_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP011018.1\|WP_001198780.1\|3979130_3979487_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.64644e-35

>NZ_CP011018.1|WP_000460535.1|3975668_3976979_+|serine-dehydratase-subunit-alpha-family-protein
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDSTAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWHGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>NZ_CP011018.1|WP_000401598.1|3974309_3975641_+|HAAAP-family-serine/threonine-permease
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>NZ_CP011018.1|WP_000622115.1|3972670_3974035_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>NZ_CP011018.1|WP_000719990.1|3972209_3972599_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP011018.1|WP_000861734.1|3969901_3972196_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP011018.1|WP_001297162.1|3968659_3969868_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP011018.1|WP_000107720.1|3967302_3968634_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP011018.1|WP_000548347.1|3966291_3967281_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NZ_CP011018.1|WP_000104211.1|3965254_3966193_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP011018.1|WP_000145820.1|3964721_3965066_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNIKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP011018.1|WP_001295544.1|3977190_3977355_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>NZ_CP011018.1|WP_000633577.1|3977377_3978079_-|pirin-family-protein
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>NZ_CP011018.1|WP_001041010.1|3978183_3979080_+|DNA-binding-transcriptional-regulator-YhaJ
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFSGK
>NZ_CP011018.1|WP_001198780.1|3979130_3979487_-|DUF805-domain-containing-protein
MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEGNSGSNRYGNDPKFGSN
>NZ_CP011018.1|WP_000384145.1|3979728_3980094_-|DUF805-domain-containing-protein
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>NZ_CP011018.1|WP_000531201.1|3980386_3981373_-|glutathionyl-hydroquinone-reductase-YqjG
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>NZ_CP011018.1|WP_001297155.1|3981442_3981925_-|DoxX-family-protein
MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>NZ_CP011018.1|WP_000096086.1|3982020_3982320_-|hypothetical-protein
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>NZ_CP011018.1|WP_000785722.1|3982309_3982714_-|hypothetical-protein
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>NZ_CP011018.1|WP_000031415.1|3982716_3983022_-|DUF883-domain-containing-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Crispr_ID: NZ_CP011018_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011018_6

4417105-4418353

Unclear

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT
TCCCCGCGCCAGCGGGGATAAACC	PILER-CR

20 spacers

The CRISPR arrays of NZ_CP011018_6

>merge|NZ_CP011018|6|4417105-4418353|CRISPRCasFinder,CRT,PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCGAGATCACACTTACCCTGCAAAATCTTAATGGGGTGTTCCCCGCGCCAGCGGGGATAAACCGACAATCACATATACGACGCGAGACGGAGATCGGTGTTCCCCGCGCCAGCGGGGATAAACCGCTACCGGGACCGTTGGTTTCCACCATGACCAGGTGTTCCCCGCGCCAGCGGGGATAAACCGGCCAATGATCCCTACTCGTACCCCCAAACGGGGTGTTCCCCGCGCCAGCGGGGATAAACCGCTGACGGAAAGCCAATTCAACGTAATCTCAGGGTGTTCCCCGCGCCAGCGGGGATAAACCGAATGGCGTTTATTTCTCCCATGTAGTGAGCTGGTGTTCCCCGCGCCAGCGGGGATAAACCGATAACAACGACACTCCGGCATATATAAAGGCAGTGTTCCCCGCGCCAGCGGGGATAAACCGGAGACGGAAATCGCGGTTGATAACGCTGATATGTGTTCCCCGCGCCAGCGGGGATAAACCGCCAAAATCCCCTAGGAATCCCAGCACGGTGCGGTGTTCCCCGCGCCAGCGGGGATAAACCTGGATCTGTGGGATTATCAACGAGGTCAAATAAGTGTTCCCCGCGCCAGCGGGGATAAACCGTCTTCAACGGTTTTGATTTCAAGTTTTTTGAGGTGTTCCCCGCGCCAGCGGGGATAAACCGCGTGCCGCTCTTGAGATCGGCGGAAAGTTTATGTGTTCCCCGCGCCAGCGGGGATAAACCGCCAGTGGAGCCGCCGCGAATTTACACACGATTGTGTTCCCCGCGCCAGCGGGGATAAACCGGCGAGGGGCAGCCGTTCGCGCTGCATGTTGATGTATTCCCCGCGCCAGCGGGGATAAACCGAAAAAACAGTGGTACTACCGCCCCGCCGAACAGTGTTCCCCGCGCCAGCGGGGATAAACCGGCGATCTCGCGGAATACACCGACGAGGCGGGCGTGTTCCCCGCGCCAGCGGGGATAAACCGTAAGGCCGTCGCCGGATCAGCCTGGCTATGCCGAGCTCCCCGCGCCAGCGGGGATAAACCGTTCTTGCGGGTGTTGCAAATATTCTTCACGTAGAGCTCCCCGCGCCAGCGGGGATAAACCGGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGTTCCCCGCGCCAGCGGGGATAAACCGGACGCCGCCGCTGCGAAGCCGTTTCCGATGTTGAGCTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP011018|6|6|4417105-4418353|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGATCACACTTACCCTGCAAAATCTTAATGGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACAATCACATATACGACGCGAGACGGAGATCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTACCGGGACCGTTGGTTTCCACCATGACCAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCCAATGATCCCTACTCGTACCCCCAAACGGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTGACGGAAAGCCAATTCAACGTAATCTCAGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATGGCGTTTATTTCTCCCATGTAGTGAGCTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATAACAACGACACTCCGGCATATATAAAGGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGACGGAAATCGCGGTTGATAACGCTGATAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAAAATCCCCTAGGAATCCCAGCACGGTGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCT	GGATCTGTGGGATTATCAACGAGGTCAAATAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCTTCAACGGTTTTGATTTCAAGTTTTTTGAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTGCCGCTCTTGAGATCGGCGGAAAGTTTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGTGGAGCCGCCGCGAATTTACACACGATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGAGGGGCAGCCGTTCGCGCTGCATGTTGAT
GTATTCCCCGCGCCAGCGGGGATAAACCG	AAAAAACAGTGGTACTACCGCCCCGCCGAACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGATCTCGCGGAATACACCGACGAGGCGGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAGGCCGTCGCCGGATCAGCCTGGCTATGCC
GAGCTCCCCGCGCCAGCGGGGATAAACCG	TTCTTGCGGGTGTTGCAAATATTCTTCACGTA
GAGCTCCCCGCGCCAGCGGGGATAAACCG	GAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCCGCCGCTGCGAAGCCGTTTCCGATGTT
GAGCTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP011018|6|1|4417105-4418353|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGATCACACTTACCCTGCAAAATCTTAATGGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACAATCACATATACGACGCGAGACGGAGATCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTACCGGGACCGTTGGTTTCCACCATGACCAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCCAATGATCCCTACTCGTACCCCCAAACGGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTGACGGAAAGCCAATTCAACGTAATCTCAGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATGGCGTTTATTTCTCCCATGTAGTGAGCTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATAACAACGACACTCCGGCATATATAAAGGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGACGGAAATCGCGGTTGATAACGCTGATAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAAAATCCCCTAGGAATCCCAGCACGGTGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCT	GGATCTGTGGGATTATCAACGAGGTCAAATAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCTTCAACGGTTTTGATTTCAAGTTTTTTGAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTGCCGCTCTTGAGATCGGCGGAAAGTTTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGTGGAGCCGCCGCGAATTTACACACGATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGAGGGGCAGCCGTTCGCGCTGCATGTTGAT
GTATTCCCCGCGCCAGCGGGGATAAACCG	AAAAAACAGTGGTACTACCGCCCCGCCGAACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGATCTCGCGGAATACACCGACGAGGCGGGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAGGCCGTCGCCGGATCAGCCTGGCTATGCC
GAGCTCCCCGCGCCAGCGGGGATAAACCG	TTCTTGCGGGTGTTGCAAATATTCTTCACGTA
GAGCTCCCCGCGCCAGCGGGGATAAACCG	GAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCCGCCGCTGCGAAGCCGTTTCCGATGTT
GAGCTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP011018|6|2|4417231-4418352|PILER-CR
TCCCCGCGCCAGCGGGGATAAACC	GCTACCGGGACCGTTGGTTTCCACCATGACCAGGTGT
TCCCCGCGCCAGCGGGGATAAACC	GGCCAATGATCCCTACTCGTACCCCCAAACGGGGTGT
TCCCCGCGCCAGCGGGGATAAACC	GCTGACGGAAAGCCAATTCAACGTAATCTCAGGGTGT
TCCCCGCGCCAGCGGGGATAAACC	GAATGGCGTTTATTTCTCCCATGTAGTGAGCTGGTGT
TCCCCGCGCCAGCGGGGATAAACC	GATAACAACGACACTCCGGCATATATAAAGGCAGTGT
TCCCCGCGCCAGCGGGGATAAACC	GGAGACGGAAATCGCGGTTGATAACGCTGATATGTGT
TCCCCGCGCCAGCGGGGATAAACC	GCCAAAATCCCCTAGGAATCCCAGCACGGTGCGGTGT
TCCCCGCGCCAGCGGGGATAAACC	TGGATCTGTGGGATTATCAACGAGGTCAAATAAGTGT
TCCCCGCGCCAGCGGGGATAAACC	GTCTTCAACGGTTTTGATTTCAAGTTTTTTGAGGTGT
TCCCCGCGCCAGCGGGGATAAACC	GCGTGCCGCTCTTGAGATCGGCGGAAAGTTTATGTGT
TCCCCGCGCCAGCGGGGATAAACC	GCCAGTGGAGCCGCCGCGAATTTACACACGATTGTGT
TCCCCGCGCCAGCGGGGATAAACC	GGCGAGGGGCAGCCGTTCGCGCTGCATGTTGATGTAT
TCCCCGCGCCAGCGGGGATAAACC	GAAAAAACAGTGGTACTACCGCCCCGCCGAACAGTGT
TCCCCGCGCCAGCGGGGATAAACC	GGCGATCTCGCGGAATACACCGACGAGGCGGGCGTGT
TCCCCGCGCCAGCGGGGATAAACC	GTAAGGCCGTCGCCGGATCAGCCTGGCTATGCCGAGC
TCCCCGCGCCAGCGGGGATAAACC	GTTCTTGCGGGTGTTGCAAATATTCTTCACGTAGAGC
TCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGT
TCCCCGCGCCAGCGGGGATAAACC	GGACGCCGCCGCTGCGAAGCCGTTTCCGATGTTGAGC
TCCCCGCGCCAGCGGGGATAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011018.1\|WP_000147666.1\|4424423_4425833_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP011018.1\|WP_001199970.1\|4416093_4416765_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP011018.1\|WP_000036723.1\|4413570_4414869_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP011018.1\|WP_001299652.1\|4425810_4426590_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP011018.1\|WP_000021321.1\|4422092_4422878_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP011018.1\|WP_000581939.1\|4410172_4410421_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP011018.1\|WP_001395988.1\|4426586_4427447_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP011018.1\|WP_000226815.1\|4407860_4410095_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP011018.1\|WP_000210878.1\|4411845_4413483_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP011018.1\|WP_001071648.1\|4410826_4411618_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP011018.1\|WP_000039693.1\|4418991_4420470_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP011018.1\|WP_001288227.1\|4415814_4415955_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011018.1\|WP_000186450.1\|4403698_4406455_-\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
NZ_CP011018.1\|WP_001164567.1\|4420496_4421774_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP011018.1\|WP_000059312.1\|4422947_4424402_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP011018.1\|WP_001130266.1\|4427594_4428170_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP011018.1\|WP_000109367.1\|4428186_4428447_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP011018.1\|WP_001347765.1\|4428437_4429709_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP011018.1\|WP_000254745.1\|4410420_4410756_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP011018.1\|WP_000046790.1\|4406511_4407813_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291

Protein	Function_ID	Function_description	E-value
NZ_CP011018.1\|WP_000147666.1\|4424423_4425833_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.50431e-51
NZ_CP011018.1\|WP_001199970.1\|4416093_4416765_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.73859e-155
NZ_CP011018.1\|WP_000036723.1\|4413570_4414869_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP011018.1\|WP_001299652.1\|4425810_4426590_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.56693e-62
NZ_CP011018.1\|WP_000021321.1\|4422092_4422878_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.84461e-140
NZ_CP011018.1\|WP_000581939.1\|4410172_4410421_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	2.78691e-47
NZ_CP011018.1\|WP_001395988.1\|4426586_4427447_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	1.15983e-87
NZ_CP011018.1\|WP_000226815.1\|4407860_4410095_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP011018.1\|WP_000210878.1\|4411845_4413483_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP011018.1\|WP_001071648.1\|4410826_4411618_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP011018.1\|WP_000039693.1\|4418991_4420470_-\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.97427e-109
NZ_CP011018.1\|WP_000186450.1\|4403698_4406455_-\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
NZ_CP011018.1\|WP_001164567.1\|4420496_4421774_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	3.44047e-29
NZ_CP011018.1\|WP_000059312.1\|4422947_4424402_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.25325e-82
NZ_CP011018.1\|WP_001130266.1\|4427594_4428170_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP011018.1\|WP_000109367.1\|4428186_4428447_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	8.55479e-42
NZ_CP011018.1\|WP_001347765.1\|4428437_4429709_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	1.51231e-125
NZ_CP011018.1\|WP_000254745.1\|4410420_4410756_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
NZ_CP011018.1\|WP_000046790.1\|4406511_4407813_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0

>NZ_CP011018.1|WP_001199970.1|4416093_4416765_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP011018.1|WP_001288227.1|4415814_4415955_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNESKITDAAVNLFIQI
>NZ_CP011018.1|WP_000036723.1|4413570_4414869_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP011018.1|WP_000210878.1|4411845_4413483_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP011018.1|WP_001071648.1|4410826_4411618_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP011018.1|WP_000254745.1|4410420_4410756_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP011018.1|WP_000581939.1|4410172_4410421_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNEITPENLHENIDWGEPKDKEVW
>NZ_CP011018.1|WP_000226815.1|4407860_4410095_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP011018.1|WP_000046790.1|4406511_4407813_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKALFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLGSLQAIRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP011018.1|WP_000186450.1|4403698_4406455_-|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG
>NZ_CP011018.1|WP_000039693.1|4418991_4420470_-|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP011018.1|WP_001164567.1|4420496_4421774_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP011018.1|WP_000021321.1|4422092_4422878_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP011018.1|WP_000059312.1|4422947_4424402_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP011018.1|WP_000147666.1|4424423_4425833_+|MFS-transporter
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP011018.1|WP_001299652.1|4425810_4426590_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP011018.1|WP_001395988.1|4426586_4427447_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSQARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQVDVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP011018.1|WP_001130266.1|4427594_4428170_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP011018.1|WP_000109367.1|4428186_4428447_-|ferredoxin-family-protein
MSVAHNLWRVADAPHIVPADSVERQMVQRLINACPAGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP011018.1|WP_001347765.1|4428437_4429709_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGVTTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: NZ_CP011018_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011018_7

4444052-4445606

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

25 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP011018_7

>merge|NZ_CP011018|7|4444052-4445606|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGCAACTGGCGGAATACAGGACGGGTGGATATTCGTGTTCCCCGCGCCAGCGGGGATAAACCGTTAGATCACACCTGGATACGAGAACAAATTGAGTGTTCCCCGCGCCAGCGGGGATAAACCGCCCGTTGAAGATCTGGACGCGTGGGGAAAAGCGTGTTCCCCGCGCCAGCGGGGATAAACCGTGCGCGGAACGGAGATTGTAAATATCAAAATCGTGTTCCCCGCGCCAGCGGGGATAAACCGACACAGGCGCGAAAACAATCGAACGCGCTAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGGAGGATGTTCGGTCCCGGAACTAAACCGGCAGTGTTCCCCGCGCCAGCGGGGATAAACCGCCGTCAGTAAACCCGCTGGCGGGTACTGGATAGTGTTCCCCGCGCCAGCGGGGATAAACCGTTTTCCCCGGCGCTAAACGGGGTAAAAAAATTGTGTTCCCCGCGCCAGCGGGGATAAACCGCGTGGAGGAGAGGGCGACGCGCTGGCAGACACGTGTTCCCCGCGCCAGCGGGGATAAACCGCGTGTCTGCCGCTGCTGAGCTGTGCGGGGATAGTGTTCCCCGCGCCAGCGGGGATAAACCGGCGCTCTCCTGAACCTCTTTCAGTCCGTCGATGTGTTCCCCGCGCCAGCGGGGATAAACCGCACCACATGAACCGCGACGCAGCGATTCACCGGTGTTCCCCGCGCCAGCGGGGATAAACCGTTGCTAACTGGCGCGAAGAGCGCGCGTGGGCTGTGTTCCCCGCGCCAGCGGGGATAAACCGACAGTGAAATATATTGGGATAACATAAAGTCGGTGTTCCCCGCGCCAGCGGGGATAAACCGGCGCACATATGAAAAAAGCCACGGGTTACGCGGTGTTCCCCGCGCCAGCGGGGATAAACCGAAACGCGGGATTACGCGCCTGTTTGAAATCTGCGTGTTCCCCGCGCCAGCGGGGATAAACCGTGATTGTGGAACATCCGTTTGACCTGCTGGCCGTGTTCCCCGCGCCAGCGGGGATAAACCGGTCTATATTATGATGAAGAGGCAACCATTGAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCAATTCATAAATTAATTTACTATTTTGAGTGCGTGTTCCCCGCGCCAGCGGGGATAAACCGACGGCGAATATAGCTGTCAACGCGCTCGACATGTGTTCCCCGCGCCAGCGGGGATAAACCGTGAGATCAAACGTTAGCCCGGCGGTAATTTGCGTGTTCCCCGCGCCAGCGGGGATAAACCGGCAATGCTCGTACGCCGTCTCACTCCGCGTGAGTGTTCCCCGCGCCAGCGGGGATAAACCGTTTATGTGGAGTATCAGTGTCTGGGTGGTAAGGTGTTCCCCGCGCCAGCGGGGATAAACCGACCTCGACAATGACACGGGCGCGAAAACAATCGTGTTCCCCGCGCCAGCGGGGATAAACCGTCGGTGGCTGGATTGAAAAAGAAGATAATCTGGTGTTCCCCGCGTCAGCGGGGATAAACCG

>NZ_CP011018|7|3|4444052-4445606|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAACTGGCGGAATACAGGACGGGTGGATATTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTAGATCACACCTGGATACGAGAACAAATTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTTGAAGATCTGGACGCGTGGGGAAAAGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCGGAACGGAGATTGTAAATATCAAAATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACACAGGCGCGAAAACAATCGAACGCGCTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGAGGATGTTCGGTCCCGGAACTAAACCGGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGTCAGTAAACCCGCTGGCGGGTACTGGATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTCCCCGGCGCTAAACGGGGTAAAAAAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTGGAGGAGAGGGCGACGCGCTGGCAGACAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTGTCTGCCGCTGCTGAGCTGTGCGGGGATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCTCTCCTGAACCTCTTTCAGTCCGTCGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACCACATGAACCGCGACGCAGCGATTCACCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCTAACTGGCGCGAAGAGCGCGCGTGGGCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACAGTGAAATATATTGGGATAACATAAAGTCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCACATATGAAAAAAGCCACGGGTTACGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAACGCGGGATTACGCGCCTGTTTGAAATCTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGATTGTGGAACATCCGTTTGACCTGCTGGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCTATATTATGATGAAGAGGCAACCATTGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAATTCATAAATTAATTTACTATTTTGAGTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCGAATATAGCTGTCAACGCGCTCGACAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGAGATCAAACGTTAGCCCGGCGGTAATTTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCAATGCTCGTACGCCGTCTCACTCCGCGTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTATGTGGAGTATCAGTGTCTGGGTGGTAAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACCTCGACAATGACACGGGCGCGAAAACAATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGGTGGCTGGATTGAAAAAGAAGATAATCTG
GTGTTCCCCGCGTCAGCGGGGATAAACCG

>NZ_CP011018|7|7|4444052-4445606|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAACTGGCGGAATACAGGACGGGTGGATATTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTAGATCACACCTGGATACGAGAACAAATTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTTGAAGATCTGGACGCGTGGGGAAAAGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCGGAACGGAGATTGTAAATATCAAAATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACACAGGCGCGAAAACAATCGAACGCGCTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGAGGATGTTCGGTCCCGGAACTAAACCGGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGTCAGTAAACCCGCTGGCGGGTACTGGATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTCCCCGGCGCTAAACGGGGTAAAAAAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTGGAGGAGAGGGCGACGCGCTGGCAGACAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTGTCTGCCGCTGCTGAGCTGTGCGGGGATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCTCTCCTGAACCTCTTTCAGTCCGTCGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACCACATGAACCGCGACGCAGCGATTCACCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCTAACTGGCGCGAAGAGCGCGCGTGGGCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACAGTGAAATATATTGGGATAACATAAAGTCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCACATATGAAAAAAGCCACGGGTTACGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAACGCGGGATTACGCGCCTGTTTGAAATCTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGATTGTGGAACATCCGTTTGACCTGCTGGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCTATATTATGATGAAGAGGCAACCATTGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAATTCATAAATTAATTTACTATTTTGAGTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCGAATATAGCTGTCAACGCGCTCGACAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGAGATCAAACGTTAGCCCGGCGGTAATTTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCAATGCTCGTACGCCGTCTCACTCCGCGTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTATGTGGAGTATCAGTGTCTGGGTGGTAAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACCTCGACAATGACACGGGCGCGAAAACAATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGGTGGCTGGATTGAAAAAGAAGATAATCTG
GTGTTCCCCGCGTCAGCGGGGATAAACCG

>NZ_CP011018|7|2|4444052-4445606|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAACTGGCGGAATACAGGACGGGTGGATATTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTAGATCACACCTGGATACGAGAACAAATTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTTGAAGATCTGGACGCGTGGGGAAAAGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCGGAACGGAGATTGTAAATATCAAAATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACACAGGCGCGAAAACAATCGAACGCGCTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGAGGATGTTCGGTCCCGGAACTAAACCGGCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGTCAGTAAACCCGCTGGCGGGTACTGGATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTCCCCGGCGCTAAACGGGGTAAAAAAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTGGAGGAGAGGGCGACGCGCTGGCAGACAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTGTCTGCCGCTGCTGAGCTGTGCGGGGATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCTCTCCTGAACCTCTTTCAGTCCGTCGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CACCACATGAACCGCGACGCAGCGATTCACCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCTAACTGGCGCGAAGAGCGCGCGTGGGCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACAGTGAAATATATTGGGATAACATAAAGTCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCACATATGAAAAAAGCCACGGGTTACGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAACGCGGGATTACGCGCCTGTTTGAAATCTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGATTGTGGAACATCCGTTTGACCTGCTGGCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCTATATTATGATGAAGAGGCAACCATTGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAATTCATAAATTAATTTACTATTTTGAGTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCGAATATAGCTGTCAACGCGCTCGACAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGAGATCAAACGTTAGCCCGGCGGTAATTTGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCAATGCTCGTACGCCGTCTCACTCCGCGTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTATGTGGAGTATCAGTGTCTGGGTGGTAAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACCTCGACAATGACACGGGCGCGAAAACAATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGGTGGCTGGATTGAAAAAGAAGATAATCTG
GTGTTCCCCGCGTCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011018.1\|WP_001233938.1\|4435396_4438096_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP011018.1\|WP_000039843.1\|4434051_4434786_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP011018.1\|WP_000568943.1\|4452002_4453052_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP011018.1\|WP_000281442.1\|4442094_4442745_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP011018.1\|WP_000517476.1\|4450486_4450798_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP011018.1\|WP_001219242.1\|4451526_4452006_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP011018.1\|WP_000206440.1\|4440300_4441356_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP011018.1\|WP_000956458.1\|4435050_4435203_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP011018.1\|WP_001246104.1\|4449969_4450293_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP011018.1\|WP_000144861.1\|4442741_4443665_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP011018.1\|WP_000246138.1\|4450816_4451527_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP011018.1\|WP_000372108.1\|4446977_4447886_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP011018.1\|WP_000490402.1\|4445688_4446726_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP011018.1\|WP_001173673.1\|4449314_4449920_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP011018.1\|WP_000029329.1\|4439752_4440289_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP011018.1\|WP_001090345.1\|4447887_4449315_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP011018.1\|WP_000085068.1\|4441366_4442113_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP011018.1\|WP_001295182.1\|4453032_4453794_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP011018.1\|WP_000063176.1\|4443661_4443955_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP011018.1\|WP_001084075.1\|4438193_4439756_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192

Protein	Function_ID	Function_description	E-value
NZ_CP011018.1\|WP_001233938.1\|4435396_4438096_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	6.43239e-178
NZ_CP011018.1\|WP_000039843.1\|4434051_4434786_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP011018.1\|WP_000568943.1\|4452002_4453052_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP011018.1\|WP_000281442.1\|4442094_4442745_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	7.04911e-92
NZ_CP011018.1\|WP_000517476.1\|4450486_4450798_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP011018.1\|WP_001219242.1\|4451526_4452006_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP011018.1\|WP_000206440.1\|4440300_4441356_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	1.62632e-155
NZ_CP011018.1\|WP_000956458.1\|4435050_4435203_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP011018.1\|WP_001246104.1\|4449969_4450293_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP011018.1\|WP_000144861.1\|4442741_4443665_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	6.67486e-158
NZ_CP011018.1\|WP_000246138.1\|4450816_4451527_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP011018.1\|WP_000372108.1\|4446977_4447886_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP011018.1\|WP_000490402.1\|4445688_4446726_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP011018.1\|WP_001173673.1\|4449314_4449920_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP011018.1\|WP_000029329.1\|4439752_4440289_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	1.12087e-29
NZ_CP011018.1\|WP_001090345.1\|4447887_4449315_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP011018.1\|WP_000085068.1\|4441366_4442113_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.95914e-49
NZ_CP011018.1\|WP_001295182.1\|4453032_4453794_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP011018.1\|WP_000063176.1\|4443661_4443955_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP011018.1\|WP_001084075.1\|4438193_4439756_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0

>NZ_CP011018.1|WP_000063176.1|4443661_4443955_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP011018.1|WP_000144861.1|4442741_4443665_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP011018.1|WP_000281442.1|4442094_4442745_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELCTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFVQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP011018.1|WP_000085068.1|4441366_4442113_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP011018.1|WP_000206440.1|4440300_4441356_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP011018.1|WP_000029329.1|4439752_4440289_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NZ_CP011018.1|WP_001084075.1|4438193_4439756_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQSSFAPKDYRRWDDIWEDGLEAEKLREALLSLEHAFQFGPDSPSFMQDFEVLMGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCSHCSALALFSLQLNAPSGGKGYRTGIRGGGPMTTLIELQEYQGNQQAPLWRKLWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQDDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLDKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLSKWNKEIWLFARQDFDERVFTNPYEPVDLERVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP011018.1|WP_001233938.1|4435396_4438096_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQESIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPTSSLSLFHSRFAFSDRQRIETKTLARFGKEGSSQRAGKALISTQVLEQSVDCDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPDEEWFGSAMRNSAYIYPDHGRIWLTQRVLRQQGAIQMPHSARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYTTGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRQDPEMANVILVTDNESCGYSATEGLIGKVG
>NZ_CP011018.1|WP_000956458.1|4435050_4435203_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP011018.1|WP_000039843.1|4434051_4434786_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP011018.1|WP_000490402.1|4445688_4446726_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP011018.1|WP_000372108.1|4446977_4447886_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP011018.1|WP_001090345.1|4447887_4449315_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARIDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPKNEAAVASSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP011018.1|WP_001173673.1|4449314_4449920_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP011018.1|WP_001246104.1|4449969_4450293_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP011018.1|WP_000517476.1|4450486_4450798_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP011018.1|WP_000246138.1|4450816_4451527_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP011018.1|WP_001219242.1|4451526_4452006_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP011018.1|WP_000568943.1|4452002_4453052_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP011018.1|WP_001295182.1|4453032_4453794_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011018_2	2.1\|1438605\|40\|NZ_CP011018\|CRISPRCasFinder	1438605-1438644	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
NZ_CP011018_1	1.1\|726461\|38\|NZ_CP011018\|CRISPRCasFinder	726461-726498	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP011018_7	7.23\|4445424\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445424-4445455	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246449-246480	2	0.938
NZ_CP011018_6	6.16\|4418049\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4418049-4418080	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	632328-632359	5	0.844
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP053858	Rhizobium pusense strain 76 plasmid pR76, complete sequence	455664-455695	5	0.844
NZ_CP011018_6	6.3\|4417256\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417256-4417287	32	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	468691-468722	7	0.781
NZ_CP011018_6	6.3\|4417256\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417256-4417287	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	428674-428705	7	0.781
NZ_CP011018_6	6.3\|4417256\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417256-4417287	32	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	628096-628127	7	0.781
NZ_CP011018_6	6.3\|4417256\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417256-4417287	32	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	768678-768709	7	0.781
NZ_CP011018_6	6.11\|4417744\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417744-4417775	32	MH807820	Dickeya phage Coodle, complete genome	4693-4724	7	0.781
NZ_CP011018_6	6.11\|4417744\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417744-4417775	32	MT857002	Salmonella phage pSal-SNUABM-02, complete genome	39215-39246	7	0.781
NZ_CP011018_6	6.12\|4417805\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417805-4417836	32	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	1028485-1028516	7	0.781
NZ_CP011018_6	6.14\|4417927\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417927-4417958	32	NZ_CP010860	Marinovum algicola DG 898 plasmid pMaD5, complete sequence	101414-101445	7	0.781
NZ_CP011018_7	7.3\|4444203\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444203-4444234	32	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	568898-568929	7	0.781
NZ_CP011018_7	7.10\|4444630\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444630-4444661	32	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	554128-554159	7	0.781
NZ_CP011018_7	7.18\|4445119\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445119-4445150	32	AP013502	Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S23-C10	12423-12454	7	0.781
NZ_CP011018_7	7.18\|4445119\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445119-4445150	32	AP013504	Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S34-C29	11382-11413	7	0.781
NZ_CP011018_7	7.18\|4445119\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445119-4445150	32	AP014448	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S35-C81, * SEQUENCING IN PROGRESS *, 2 ordered pieces	27318-27349	7	0.781
NZ_CP011018_7	7.18\|4445119\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445119-4445150	32	GU943055	Uncultured phage MedDCM-OCT-S04-C26 genomic sequence	10843-10874	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP038925	Piscirickettsia salmonis strain Psal-011 plasmid unnamed2, complete sequence	67773-67804	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP038813	Piscirickettsia salmonis strain Psal-001 plasmid unnamed2, complete sequence	67772-67803	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP033943	Piscirickettsia salmonis strain EM-90 plasmid pPSEM90-6, complete sequence	12989-13020	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP013780	Piscirickettsia salmonis strain PM51819A plasmid p2PS5, complete sequence	23366-23397	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP013780	Piscirickettsia salmonis strain PM51819A plasmid p2PS5, complete sequence	106638-106669	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP038915	Piscirickettsia salmonis strain Psal-010a plasmid unnamed2, complete sequence	67772-67803	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP038934	Piscirickettsia salmonis strain Psal-025 plasmid unnamed2, complete sequence	68061-68092	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP038974	Piscirickettsia salmonis strain Psal-069 plasmid unnamed2, complete sequence	2467-2498	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP038888	Piscirickettsia salmonis strain Psal-004 plasmid unnamed2, complete sequence	67774-67805	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP039216	Piscirickettsia salmonis strain Psal-104a plasmid unnamed2, complete sequence	2467-2498	7	0.781
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_CP038878	Piscirickettsia salmonis strain Psal-002 plasmid unnamed2, complete sequence	67773-67804	7	0.781
NZ_CP011018_6	6.3\|4417256\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417256-4417287	32	NC_010811	Ralstonia phage RSL1, complete genome	67286-67317	8	0.75
NZ_CP011018_6	6.3\|4417256\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417256-4417287	32	AB366653	Ralstonia phage RSL1 DNA, complete genome	67286-67317	8	0.75
NZ_CP011018_6	6.12\|4417805\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417805-4417836	32	KX752698	Mycobacterium phage Tonenili, complete genome	136893-136924	8	0.75
NZ_CP011018_6	6.14\|4417927\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417927-4417958	32	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	347166-347197	8	0.75
NZ_CP011018_6	6.16\|4418049\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4418049-4418080	32	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	460575-460606	8	0.75
NZ_CP011018_6	6.19\|4418232\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4418232-4418263	32	MK814759	Gordonia phage Reyja, complete genome	4467-4498	8	0.75
NZ_CP011018_6	6.20\|4418293\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4418293-4418324	32	NZ_CP040452	Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence	1326-1357	8	0.75
NZ_CP011018_7	7.7\|4444447\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444447-4444478	32	KY555145	Caulobacter phage Ccr29, complete genome	57425-57456	8	0.75
NZ_CP011018_7	7.7\|4444447\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444447-4444478	32	KY555143	Caulobacter phage Ccr2, complete genome	52892-52923	8	0.75
NZ_CP011018_7	7.7\|4444447\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444447-4444478	32	NC_019407	Caulobacter phage CcrMagneto, complete genome	51760-51791	8	0.75
NZ_CP011018_7	7.7\|4444447\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444447-4444478	32	KY555144	Caulobacter phage Ccr5, complete genome	52344-52375	8	0.75
NZ_CP011018_7	7.7\|4444447\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444447-4444478	32	KY555142	Caulobacter phage Ccr10, complete genome	52417-52448	8	0.75
NZ_CP011018_7	7.9\|4444569\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444569-4444600	32	NZ_CP042998	Aquisphaera giovannonii strain OJF2 plasmid pOJF2_1, complete sequence	10981-11012	8	0.75
NZ_CP011018_7	7.10\|4444630\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444630-4444661	32	NC_013698	Clavibacter phage CMP1, complete genome	17341-17372	8	0.75
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	MN693954	Marine virus AFVG_250M569, complete genome	38213-38244	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	270741-270772	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	1429126-1429157	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	450512-450543	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	1363718-1363749	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	259589-259620	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	156145-156176	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP021819	Sinorhizobium meliloti strain M162 plasmid psymA, complete sequence	108131-108162	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	136871-136902	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	308731-308762	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	386165-386196	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	1141409-1141440	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	239251-239282	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	1491172-1491203	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	173783-173814	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP019483	Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence	251909-251940	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NZ_CP019486	Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence	227862-227893	8	0.75
NZ_CP011018_7	7.20\|4445241\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445241-4445272	32	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	270403-270434	8	0.75
NZ_CP011018_7	7.25\|4445546\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445546-4445577	32	HM029250	Lactococcus phage 949, complete genome	55071-55102	8	0.75
NZ_CP011018_6	6.1\|4417134\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417134-4417165	32	MH719082	Escherichia phage vB_EcoM_IME392, complete genome	494-525	9	0.719
NZ_CP011018_6	6.8\|4417561\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417561-4417592	32	AP014303	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S29-C153, * SEQUENCING IN PROGRESS *	4922-4953	9	0.719
NZ_CP011018_6	6.12\|4417805\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417805-4417836	32	NZ_CP039905	Agrobacterium tumefaciens strain CFBP6623 plasmid pAtCFBP6623a, complete sequence	175988-176019	9	0.719
NZ_CP011018_6	6.12\|4417805\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417805-4417836	32	NZ_CP039909	Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence	115836-115867	9	0.719
NZ_CP011018_6	6.12\|4417805\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417805-4417836	32	NZ_LS974446	Rhizobium selenitireducens ATCC BAA-1503 isolate T2.30D-1.1_plasmid plasmid 1, complete sequence	14981-15012	9	0.719
NZ_CP011018_6	6.14\|4417927\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417927-4417958	32	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	89227-89258	9	0.719
NZ_CP011018_6	6.14\|4417927\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417927-4417958	32	NZ_CP021083	Deinococcus ficus strain CC-FR2-10 plasmid pDFI2, complete sequence	361520-361551	9	0.719
NZ_CP011018_6	6.16\|4418049\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4418049-4418080	32	NZ_CP006988	Rhizobium sp. IE4771 plasmid pRetIE4771b, complete sequence	91348-91379	9	0.719
NZ_CP011018_6	6.17\|4418110\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4418110-4418141	32	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	224876-224907	9	0.719
NZ_CP011018_7	7.3\|4444203\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444203-4444234	32	NZ_CP016500	Agrobacterium sp. RAC06 plasmid pBSY240_1, complete sequence	217061-217092	9	0.719
NZ_CP011018_7	7.9\|4444569\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444569-4444600	32	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	24517-24548	9	0.719
NZ_CP011018_7	7.10\|4444630\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444630-4444661	32	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	5027-5058	9	0.719
NZ_CP011018_7	7.11\|4444691\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444691-4444722	32	MN013089	Bacillus phage vB_BspM_MarvelLand, complete genome	88488-88519	9	0.719
NZ_CP011018_7	7.11\|4444691\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444691-4444722	32	KT187252	Bacillus phage PBC6, complete genome	88037-88068	9	0.719
NZ_CP011018_7	7.11\|4444691\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444691-4444722	32	KX987999	Bacillus phage BCP12, complete genome	55533-55564	9	0.719
NZ_CP011018_7	7.11\|4444691\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444691-4444722	32	JN797797	Bacillus phage BCP78, complete genome	86600-86631	9	0.719
NZ_CP011018_7	7.11\|4444691\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444691-4444722	32	NC_047735	Bacillus phage BCU4, complete genome	78934-78965	9	0.719
NZ_CP011018_7	7.11\|4444691\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444691-4444722	32	MH487649	Bacillus phage BC01, complete genome	89273-89304	9	0.719
NZ_CP011018_7	7.11\|4444691\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444691-4444722	32	KT224359	Bacillus phage TsarBomba, complete genome	98734-98765	9	0.719
NZ_CP011018_7	7.13\|4444813\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444813-4444844	32	NZ_CP029096	Pseudomonas aeruginosa strain AR439 plasmid unnamed2, complete sequence	245017-245048	9	0.719
NZ_CP011018_7	7.13\|4444813\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444813-4444844	32	MF344569	Pseudomonas aeruginosa plasmid p12939-PER, complete sequence	267220-267251	9	0.719
NZ_CP011018_7	7.13\|4444813\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444813-4444844	32	NZ_MH547560	Pseudomonas aeruginosa strain PA34 plasmid pMKPA34-1, complete sequence	83416-83447	9	0.719
NZ_CP011018_7	7.14\|4444874\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444874-4444905	32	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	97609-97640	9	0.719
NZ_CP011018_7	7.14\|4444874\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444874-4444905	32	NZ_CP035233	Bacillus glycinifermentans strain SRCM103574 plasmid unnamed1, complete sequence	14374-14405	9	0.719
NZ_CP011018_7	7.21\|4445302\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445302-4445333	32	MT708550	Achromobacter phage Mano, complete genome	2686-2717	9	0.719
NZ_CP011018_6	6.8\|4417561\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417561-4417592	32	MK250016	Prevotella phage Lak-A1, complete genome	348544-348575	10	0.688
NZ_CP011018_6	6.10\|4417683\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417683-4417714	32	MT856905	Enterococcus phage vB_EfaM_A2, complete genome	20447-20478	10	0.688
NZ_CP011018_6	6.10\|4417683\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417683-4417714	32	MW004544	Enterococcus phage EFGrKN, complete genome	18980-19011	10	0.688
NZ_CP011018_6	6.10\|4417683\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417683-4417714	32	MN241318	Enterococcus phage PEf771, complete genome	101150-101181	10	0.688
NZ_CP011018_6	6.10\|4417683\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417683-4417714	32	NC_029009	Enterococcus phage EFDG1, complete genome	19024-19055	10	0.688
NZ_CP011018_6	6.10\|4417683\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417683-4417714	32	MH880817	Enterococcus phage EfV12-phi1, complete genome	21449-21480	10	0.688
NZ_CP011018_6	6.10\|4417683\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417683-4417714	32	MN027503	Enterococcus phage vB_OCPT_Ben, complete genome	131391-131422	10	0.688
NZ_CP011018_6	6.14\|4417927\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417927-4417958	32	NZ_CP019037	Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence	354311-354342	10	0.688
NZ_CP011018_6	6.20\|4418293\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4418293-4418324	32	NZ_CP012383	Streptomyces ambofaciens ATCC 23877 plasmid pSAM1, complete sequence	14130-14161	10	0.688
NZ_CP011018_7	7.3\|4444203\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444203-4444234	32	NZ_CP045856	Agrobacterium sp. MA01 plasmid punanmed2, complete sequence	262994-263025	10	0.688
NZ_CP011018_7	7.9\|4444569\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444569-4444600	32	NZ_CP017589	Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ08, complete sequence	91030-91061	10	0.688
NZ_CP011018_7	7.9\|4444569\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444569-4444600	32	MN882551	Butyrivibrio virus Arian, complete genome	24528-24559	10	0.688
NZ_CP011018_7	7.9\|4444569\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444569-4444600	32	MN882552	Butyrivibrio virus Bo-Finn, complete genome	24295-24326	10	0.688
NZ_CP011018_7	7.10\|4444630\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444630-4444661	32	NZ_CP016291	Rhizobium leguminosarum strain Vaf10 plasmid unnamed6, complete sequence	180043-180074	10	0.688
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_LR215032	Mycoplasma gallopavonis strain NCTC10186 plasmid 2	248908-248939	10	0.688
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	NZ_LR214943	Mycoplasma orale strain NCTC10112 plasmid 4	4361-4392	10	0.688
NZ_CP011018_6	6.8\|4417561\|32\|NZ_CP011018\|CRISPRCasFinder,CRT	4417561-4417592	32	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1997929-1997960	11	0.656
NZ_CP011018_7	7.14\|4444874\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4444874-4444905	32	MF417930	Uncultured Caudovirales phage clone 3S_1, partial genome	23786-23817	11	0.656
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	MT074146	Bacteroides phage SJC03, complete genome	43513-43544	11	0.656
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	MT074139	Bacteroides phage DAC19, complete genome	51210-51241	11	0.656
NZ_CP011018_7	7.19\|4445180\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445180-4445211	32	MT074140	Bacteroides phage DAC20, complete genome	51210-51241	11	0.656
NZ_CP011018_7	7.22\|4445363\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445363-4445394	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1789771-1789802	11	0.656
NZ_CP011018_7	7.22\|4445363\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445363-4445394	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	23490-23521	11	0.656
NZ_CP011018_7	7.25\|4445546\|32\|NZ_CP011018\|PILER-CR,CRISPRCasFinder,CRT	4445546-4445577	32	NC_009760	Bacillus phage 0305phi8-36, complete genome	157057-157088	11	0.656

1. spacer 2.1|1438605|40|NZ_CP011018|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 1.1|726461|38|NZ_CP011018|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

3. spacer 7.23|4445424|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 2, identity: 0.938

tttatgtggagtatcagtgtctgggtggtaag	CRISPR spacer
tttatgtggagtatcagtgcctgggtggaaag	Protospacer
*******************.******** ***

4. spacer 6.16|4418049|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 5, identity: 0.844

gcgatctcgcggaatacaccgacg-aggcgggc	CRISPR spacer
acgatctcgcggaatacgtcgacgtaggccgg-	Protospacer
.****************..***** **** **

5. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053858 (Rhizobium pusense strain 76 plasmid pR76, complete sequence) position: , mismatch: 5, identity: 0.844

acggcg-aatatagctgtcaacgcgctcgacat	CRISPR spacer
-tggcgcaatatagctgtcgacgcgctcgtcaa	Protospacer
 .**** ************.********* **

6. spacer 6.3|4417256|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.781

ctaccgggaccgttggtttccaccatgaccag	CRISPR spacer
gcgccgggccagttggtttccaccatgatccg	Protospacer
 ..***** * *****************.* *

7. spacer 6.3|4417256|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 7, identity: 0.781

ctaccgggaccgttggtttccaccatgaccag	CRISPR spacer
gcgccgggccagttggtttccaccatgatccg	Protospacer
 ..***** * *****************.* *

8. spacer 6.3|4417256|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 7, identity: 0.781

ctaccgggaccgttggtttccaccatgaccag	CRISPR spacer
gcgccgggccagttggtttccaccatgatccg	Protospacer
 ..***** * *****************.* *

9. spacer 6.3|4417256|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

ctaccgggaccgttggtttccaccatgaccag	CRISPR spacer
gcgccgggccagttggtttccaccatgatccg	Protospacer
 ..***** * *****************.* *

10. spacer 6.11|4417744|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MH807820 (Dickeya phage Coodle, complete genome) position: , mismatch: 7, identity: 0.781

---tcttcaacggttttgatttcaagttttttgag	CRISPR spacer
ggggctt---cggttttgatttcaactttcttgac	Protospacer
    ***   *************** ***.****

11. spacer 6.11|4417744|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MT857002 (Salmonella phage pSal-SNUABM-02, complete genome) position: , mismatch: 7, identity: 0.781

---tcttcaacggttttgatttcaagttttttgag	CRISPR spacer
ggggctt---cggttttgatttcaactttcttgac	Protospacer
    ***   *************** ***.****

12. spacer 6.12|4417805|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 7, identity: 0.781

cgtgccgctcttgagatcggcgg-aaagtttat	CRISPR spacer
cgtggcgttcttgagatcggcggtgtcgtttg-	Protospacer
**** **.*************** .  ****.

13. spacer 6.14|4417927|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP010860 (Marinovum algicola DG 898 plasmid pMaD5, complete sequence) position: , mismatch: 7, identity: 0.781

gcgagggg---cagccgttcgcgctgcatgttgat	CRISPR spacer
---agcgatttcagccgttcgagctgcatgtggat	Protospacer
   ** *.   ********** ********* ***

14. spacer 7.3|4444203|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

cccgttga--agatctggacgcgtggggaaaagc	CRISPR spacer
--ggttcacgagatctggacgcgtggcgataagt	Protospacer
   *** *  **************** ** ***.

15. spacer 7.10|4444630|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 7, identity: 0.781

-cgtgtctgccgctgctgagctgtgcggggata	CRISPR spacer
ccgcg-ctgccgctgctgatccgtgcgggtctg	Protospacer
 **.* ************* *.*******  *.

16. spacer 7.18|4445119|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to AP013502 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S23-C10) position: , mismatch: 7, identity: 0.781

gtctatattatgatgaagaggcaaccattgaa	CRISPR spacer
ttaaatattgtgatgaagaggcaaccttttat	Protospacer
 *  *****.**************** ** *

17. spacer 7.18|4445119|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to AP013504 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G2, isolate: uvMED-CGR-C14A-MedDCM-OCT-S34-C29) position: , mismatch: 7, identity: 0.781

gtctatattatgatgaagaggcaaccattgaa	CRISPR spacer
ttaaatattgtgatgaagaggcaaccttttat	Protospacer
 *  *****.**************** ** *

18. spacer 7.18|4445119|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to AP014448 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C14A-MedDCM-OCT-S35-C81, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 7, identity: 0.781

gtctatattatgatgaagaggcaaccattgaa	CRISPR spacer
ttaaatattgtgatgaagaggcaaccttttat	Protospacer
 *  *****.**************** ** *

19. spacer 7.18|4445119|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to GU943055 (Uncultured phage MedDCM-OCT-S04-C26 genomic sequence) position: , mismatch: 7, identity: 0.781

gtctatattatgatgaagaggcaaccattgaa	CRISPR spacer
ttaaatattgtgatgaagaggcaaccttttat	Protospacer
 *  *****.**************** ** *

20. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038925 (Piscirickettsia salmonis strain Psal-011 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

21. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038813 (Piscirickettsia salmonis strain Psal-001 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

22. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033943 (Piscirickettsia salmonis strain EM-90 plasmid pPSEM90-6, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

23. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013780 (Piscirickettsia salmonis strain PM51819A plasmid p2PS5, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

24. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013780 (Piscirickettsia salmonis strain PM51819A plasmid p2PS5, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

25. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038915 (Piscirickettsia salmonis strain Psal-010a plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

26. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038934 (Piscirickettsia salmonis strain Psal-025 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

27. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038974 (Piscirickettsia salmonis strain Psal-069 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

28. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038888 (Piscirickettsia salmonis strain Psal-004 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

29. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039216 (Piscirickettsia salmonis strain Psal-104a plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

30. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038878 (Piscirickettsia salmonis strain Psal-002 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

caattcataaattaatttactattttgagtgc-	CRISPR spacer
atatttataaattaatttacta-tttgctcgcc	Protospacer
  ***.**************** ****  .**

31. spacer 6.3|4417256|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NC_010811 (Ralstonia phage RSL1, complete genome) position: , mismatch: 8, identity: 0.75

ctaccgggaccgttggtttccaccatgaccag	CRISPR spacer
gtacccggaccgttggtttccaccagattcca	Protospacer
 **** ******************* . .* .

32. spacer 6.3|4417256|32|NZ_CP011018|CRISPRCasFinder,CRT matches to AB366653 (Ralstonia phage RSL1 DNA, complete genome) position: , mismatch: 8, identity: 0.75

ctaccgggaccgttggtttccaccatgaccag	CRISPR spacer
gtacccggaccgttggtttccaccagattcca	Protospacer
 **** ******************* . .* .

33. spacer 6.12|4417805|32|NZ_CP011018|CRISPRCasFinder,CRT matches to KX752698 (Mycobacterium phage Tonenili, complete genome) position: , mismatch: 8, identity: 0.75

cgtgccgctcttgagatcggcggaaagtttat	CRISPR spacer
cgcaccgctcttgagcttggcggaaagcaggt	Protospacer
**..*********** *.*********.  .*

34. spacer 6.14|4417927|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

gcgaggggcagccgttcgcgctgca--tgttgat	CRISPR spacer
tggagtcgcagccgttcgcgctgcaggcgctg--	Protospacer
  ***  ******************  .*.**

35. spacer 6.16|4418049|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gcgatctcgcggaatacaccgacgaggcgggc	CRISPR spacer
gcctgctggcggaatacgccgacgaggcgacg	Protospacer
**   ** *********.***********.

36. spacer 6.19|4418232|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 8, identity: 0.75

gagcctgacgagactactgaggccgttctgtc-	CRISPR spacer
aagcctgacgaggctactggggcca-gcggtgg	Protospacer
.***********.******.****.  * **

37. spacer 6.20|4418293|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP040452 (Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gacgccgccgctgcgaagccgtttccgatgtt	CRISPR spacer
cgcgctgacgctgcgaagccgtttccgccact	Protospacer
 .***.* ******************* ...*

38. spacer 7.7|4444447|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to KY555145 (Caulobacter phage Ccr29, complete genome) position: , mismatch: 8, identity: 0.75

ccgtcagtaaacccgctggcgggt-actggata	CRISPR spacer
ccgtcagcaatcccgctggcgggtcgtttcgt-	Protospacer
*******.** ************* ..*  .*

39. spacer 7.7|4444447|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to KY555143 (Caulobacter phage Ccr2, complete genome) position: , mismatch: 8, identity: 0.75

ccgtcagtaaacccgctggcgggt-actggata	CRISPR spacer
ccgtcagcaatcccgctggcgggtcgtttcgt-	Protospacer
*******.** ************* ..*  .*

40. spacer 7.7|4444447|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_019407 (Caulobacter phage CcrMagneto, complete genome) position: , mismatch: 8, identity: 0.75

ccgtcagtaaacccgctggcgggt-actggata	CRISPR spacer
ccgtcagcaatcccgctggcgggtcgtttcgt-	Protospacer
*******.** ************* ..*  .*

41. spacer 7.7|4444447|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to KY555144 (Caulobacter phage Ccr5, complete genome) position: , mismatch: 8, identity: 0.75

ccgtcagtaaacccgctggcgggt-actggata	CRISPR spacer
ccgtcagcaatcccgctggcgggtcgtttcgt-	Protospacer
*******.** ************* ..*  .*

42. spacer 7.7|4444447|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to KY555142 (Caulobacter phage Ccr10, complete genome) position: , mismatch: 8, identity: 0.75

ccgtcagtaaacccgctggcgggt-actggata	CRISPR spacer
ccgtcagcaatcccgctggcgggtcgtttcgt-	Protospacer
*******.** ************* ..*  .*

43. spacer 7.9|4444569|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042998 (Aquisphaera giovannonii strain OJF2 plasmid pOJF2_1, complete sequence) position: , mismatch: 8, identity: 0.75

cgtggaggagagggcgacgcgctggcagacac	CRISPR spacer
ccagcaggagcgggagacgcgctggcagaaga	Protospacer
*  * ***** *** ************** .

44. spacer 7.10|4444630|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_013698 (Clavibacter phage CMP1, complete genome) position: , mismatch: 8, identity: 0.75

cgtgtctgccgctgctgagctgtgcggggata	CRISPR spacer
cgagcgccccgctgctgagctgcacggggatc	Protospacer
** *. . **************..*******

45. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MN693954 (Marine virus AFVG_250M569, complete genome) position: , mismatch: 8, identity: 0.75

caattcataaattaatttactattttgagtgc	CRISPR spacer
agattcataattgaatttactatttttcttga	Protospacer
 .******** * *************   **

46. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

47. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

48. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

49. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

50. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

51. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

52. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021819 (Sinorhizobium meliloti strain M162 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

53. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

54. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

55. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

56. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

57. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

58. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

59. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

60. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019483 (Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

61. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019486 (Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

62. spacer 7.20|4445241|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.75

acggcgaatatagctgtcaacgcgctcgacat	CRISPR spacer
atgccgaatatagctgttaatgcgctcaaacc	Protospacer
*.* *************.**.******.*  .

63. spacer 7.25|4445546|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to HM029250 (Lactococcus phage 949, complete genome) position: , mismatch: 8, identity: 0.75

tcggtggctggattgaaaaagaagata---atctg	CRISPR spacer
atggtggctggacagaaaaagaagagatagat---	Protospacer
 .**********. *********** *   **

64. spacer 6.1|4417134|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MH719082 (Escherichia phage vB_EcoM_IME392, complete genome) position: , mismatch: 9, identity: 0.719

agatcacacttaccctgcaaaatcttaatggg	CRISPR spacer
tcgttacacttacccagcaaagtcttaactga	Protospacer
  .*.********** *****.******. *.

65. spacer 6.8|4417561|32|NZ_CP011018|CRISPRCasFinder,CRT matches to AP014303 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S29-C153, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

gagacggaaatcgcggttgataacgctgatat	CRISPR spacer
ggcgaggaagtcgcggttgataaagctgctgc	Protospacer
*. . ****.************* **** *..

66. spacer 6.12|4417805|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP039905 (Agrobacterium tumefaciens strain CFBP6623 plasmid pAtCFBP6623a, complete sequence) position: , mismatch: 9, identity: 0.719

cgtgccgctcttgagatcggcggaaagtttat	CRISPR spacer
ggcgccgcgcttgagatcggtggaaaggccgc	Protospacer
 *.***** ***********.****** ....

67. spacer 6.12|4417805|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP039909 (Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence) position: , mismatch: 9, identity: 0.719

cgtgccgctcttgagatcggcggaaagtttat	CRISPR spacer
ggcgccgcgcttgagatcggtggaaaggccgc	Protospacer
 *.***** ***********.****** ....

68. spacer 6.12|4417805|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_LS974446 (Rhizobium selenitireducens ATCC BAA-1503 isolate T2.30D-1.1_plasmid plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

cgtgccgctcttgagatcggcggaaagtttat	CRISPR spacer
ggcgccgcgcttgagatcggtggaaaggccgc	Protospacer
 *.***** ***********.****** ....

69. spacer 6.14|4417927|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

gcgaggggcagccgttcgcgctgcatgttgat	CRISPR spacer
gcgaggcgctgccgttcgcgctggaactcctg	Protospacer
****** ** ************* *  *.

70. spacer 6.14|4417927|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP021083 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI2, complete sequence) position: , mismatch: 9, identity: 0.719

gcgaggggcagccgttcgcgctgcatgttgat	CRISPR spacer
tcgaggggcagccgctggcgctgctcgaaggc	Protospacer
 *************.* ******* .*  *..

71. spacer 6.16|4418049|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP006988 (Rhizobium sp. IE4771 plasmid pRetIE4771b, complete sequence) position: , mismatch: 9, identity: 0.719

gcgatctcgcggaatacaccgacgaggcgggc	CRISPR spacer
cgcacgtcgcggattacatcgacgaggcggta	Protospacer
   *. ******* ****.***********

72. spacer 6.17|4418110|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

taaggccgtcgccggatcagcctggctatgcc	CRISPR spacer
cggggccgtcgccggatcagccggtctgctgc	Protospacer
...******************* * **..  *

73. spacer 7.3|4444203|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016500 (Agrobacterium sp. RAC06 plasmid pBSY240_1, complete sequence) position: , mismatch: 9, identity: 0.719

cccgttgaagatctggacgcgtggggaaaagc	CRISPR spacer
cgcagacaagatctggccgcgttgggaaaatg	Protospacer
* *.   ********* ***** *******

74. spacer 7.9|4444569|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 9, identity: 0.719

cgtggaggagagggcgacgcgctggcagacac	CRISPR spacer
gatggaggagggggcgacgcgcaggccgcttt	Protospacer
 .********.*********** *** * . .

75. spacer 7.10|4444630|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 9, identity: 0.719

cgtgtctgccgctgctgagctgtgcggggata	CRISPR spacer
tgaatatgccgctgctgagctatgccggggag	Protospacer
.* .* ***************.*** ***. .

76. spacer 7.11|4444691|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MN013089 (Bacillus phage vB_BspM_MarvelLand, complete genome) position: , mismatch: 9, identity: 0.719

gcgctctcctgaacctctttcagtccgtcgat	CRISPR spacer
gcgctctgctgaacctctttcagataacggta	Protospacer
******* *************** . .. *

77. spacer 7.11|4444691|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to KT187252 (Bacillus phage PBC6, complete genome) position: , mismatch: 9, identity: 0.719

gcgctctcctgaacctctttcagtccgtcgat	CRISPR spacer
gcgttctgctgaacctctttcagatagcggta	Protospacer
***.*** *************** . *. *

78. spacer 7.11|4444691|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to KX987999 (Bacillus phage BCP12, complete genome) position: , mismatch: 9, identity: 0.719

gcgctctcctgaacctctttcagtccgtcgat	CRISPR spacer
gcgttctgctgaacctctttcagatagcggta	Protospacer
***.*** *************** . *. *

79. spacer 7.11|4444691|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to JN797797 (Bacillus phage BCP78, complete genome) position: , mismatch: 9, identity: 0.719

gcgctctcctgaacctctttcagtccgtcgat	CRISPR spacer
gcgttctgctgaacctctttcagatagcggta	Protospacer
***.*** *************** . *. *

80. spacer 7.11|4444691|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_047735 (Bacillus phage BCU4, complete genome) position: , mismatch: 9, identity: 0.719

gcgctctcctgaacctctttcagtccgtcgat	CRISPR spacer
gcgttctgctgaacctctttcagatagcggta	Protospacer
***.*** *************** . *. *

81. spacer 7.11|4444691|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MH487649 (Bacillus phage BC01, complete genome) position: , mismatch: 9, identity: 0.719

gcgctctcctgaacctctttcagtccgtcgat	CRISPR spacer
gcgttctgctgaacctctttcagatagcggta	Protospacer
***.*** *************** . *. *

82. spacer 7.11|4444691|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to KT224359 (Bacillus phage TsarBomba, complete genome) position: , mismatch: 9, identity: 0.719

gcgctctcctgaacctctttcagtccgtcgat	CRISPR spacer
gcgttctgctgaacctctttcagatagcggta	Protospacer
***.*** *************** . *. *

83. spacer 7.13|4444813|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029096 (Pseudomonas aeruginosa strain AR439 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgctaactggcgcgaagagcgcgcgtgggct	CRISPR spacer
ctgctacctggcgcaaagagcgcggtggcgaa	Protospacer
.***** *******.*********   * *

84. spacer 7.13|4444813|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MF344569 (Pseudomonas aeruginosa plasmid p12939-PER, complete sequence) position: , mismatch: 9, identity: 0.719

ttgctaactggcgcgaagagcgcgcgtgggct	CRISPR spacer
ctgctacctggcgcaaagagcgcggtggcgaa	Protospacer
.***** *******.*********   * *

85. spacer 7.13|4444813|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH547560 (Pseudomonas aeruginosa strain PA34 plasmid pMKPA34-1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgctaactggcgcgaagagcgcgcgtgggct	CRISPR spacer
ctgctacctggcgcaaagagcgcggtggcgaa	Protospacer
.***** *******.*********   * *

86. spacer 7.14|4444874|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 9, identity: 0.719

acagtgaaatatattgggataacataaagtcg	CRISPR spacer
gctattaaatatattggaataacagaaagagt	Protospacer
.* .* ***********.****** ****

87. spacer 7.14|4444874|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035233 (Bacillus glycinifermentans strain SRCM103574 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

acagtgaaatatattgggataacataaagtcg	CRISPR spacer
acacttaaatatattgggataacggacgatga	Protospacer
*** * *****************. * ..* .

88. spacer 7.21|4445302|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MT708550 (Achromobacter phage Mano, complete genome) position: , mismatch: 9, identity: 0.719

tgagatcaaacgttagcccggcggtaatttgc	CRISPR spacer
ggcggtcaaaggtaagcccggcggtaatgcta	Protospacer
 * *.***** ** ************** .

89. spacer 6.8|4417561|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MK250016 (Prevotella phage Lak-A1, complete genome) position: , mismatch: 10, identity: 0.688

gagacggaaatcgcggttgataacgctgatat	CRISPR spacer
tactttcttatcgcggttgataaagatgatat	Protospacer
 *  .    ************** * ******

90. spacer 6.10|4417683|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MT856905 (Enterococcus phage vB_EfaM_A2, complete genome) position: , mismatch: 10, identity: 0.688

ggatctgtgggattatcaacgaggtcaaataa	CRISPR spacer
ctcagtgtggtattatcaaggaggtcaagaga	Protospacer
     ***** ******** ********. .*

91. spacer 6.10|4417683|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MW004544 (Enterococcus phage EFGrKN, complete genome) position: , mismatch: 10, identity: 0.688

ggatctgtgggattatcaacgaggtcaaataa	CRISPR spacer
ctcagtgtggtattatcaaggaggtcaagaga	Protospacer
     ***** ******** ********. .*

92. spacer 6.10|4417683|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MN241318 (Enterococcus phage PEf771, complete genome) position: , mismatch: 10, identity: 0.688

ggatctgtgggattatcaacgaggtcaaataa	CRISPR spacer
ctcagtgtggtattatcaaggaggtcaagaga	Protospacer
     ***** ******** ********. .*

93. spacer 6.10|4417683|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NC_029009 (Enterococcus phage EFDG1, complete genome) position: , mismatch: 10, identity: 0.688

ggatctgtgggattatcaacgaggtcaaataa	CRISPR spacer
ttcagtgtggtattatcaaggaggtcaagaga	Protospacer
     ***** ******** ********. .*

94. spacer 6.10|4417683|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MH880817 (Enterococcus phage EfV12-phi1, complete genome) position: , mismatch: 10, identity: 0.688

ggatctgtgggattatcaacgaggtcaaataa	CRISPR spacer
ctcagtgtggtattatcaaggaggtcaagaga	Protospacer
     ***** ******** ********. .*

95. spacer 6.10|4417683|32|NZ_CP011018|CRISPRCasFinder,CRT matches to MN027503 (Enterococcus phage vB_OCPT_Ben, complete genome) position: , mismatch: 10, identity: 0.688

ggatctgtgggattatcaacgaggtcaaataa	CRISPR spacer
ctcagtgtggtattatcaaggaggtcaagaga	Protospacer
     ***** ******** ********. .*

96. spacer 6.14|4417927|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP019037 (Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

gcgaggggcagccgttcgcgctgcatgttgat	CRISPR spacer
tcccggggcagccgttcgcgatgaatgaaacc	Protospacer
 *  **************** ** ***  . .

97. spacer 6.20|4418293|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP012383 (Streptomyces ambofaciens ATCC 23877 plasmid pSAM1, complete sequence) position: , mismatch: 10, identity: 0.688

gacgccgccgctgcgaagccgtttccgatgtt	CRISPR spacer
ttgcccgccgcggcgaagccgcttccgtcctc	Protospacer
    ******* *********.***** . *.

98. spacer 7.3|4444203|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045856 (Agrobacterium sp. MA01 plasmid punanmed2, complete sequence) position: , mismatch: 10, identity: 0.688

cccgttgaagatctggacgcgtggggaaaagc	CRISPR spacer
tgcagacaagatctggccgcgttgggaaaatg	Protospacer
. *.   ********* ***** *******

99. spacer 7.9|4444569|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017589 (Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ08, complete sequence) position: , mismatch: 10, identity: 0.688

cgtggaggagagggcgacgcgctggcagacac	CRISPR spacer
aaaagcaaagtgggcaacgcgctggcagacat	Protospacer
 . .* ..** ****.***************.

100. spacer 7.9|4444569|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MN882551 (Butyrivibrio virus Arian, complete genome) position: , mismatch: 10, identity: 0.688

cgtggaggagagggcgacgcgctggcagacac	CRISPR spacer
atttttggagagggcgacgcgccgacagattg	Protospacer
  *   ****************.*.****.

101. spacer 7.9|4444569|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MN882552 (Butyrivibrio virus Bo-Finn, complete genome) position: , mismatch: 10, identity: 0.688

cgtggaggagagggcgacgcgctggcagacac	CRISPR spacer
atttttggagagggcgacgcgccgacagattg	Protospacer
  *   ****************.*.****.

102. spacer 7.10|4444630|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016291 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed6, complete sequence) position: , mismatch: 10, identity: 0.688

cgtgtctgccgctgctgagctgtgcggggata	CRISPR spacer
tcagtctgccgccgctgacctgtgcgaaggcg	Protospacer
.  *********.***** *******..*...

103. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR215032 (Mycoplasma gallopavonis strain NCTC10186 plasmid 2) position: , mismatch: 10, identity: 0.688

caattcataaattaatttactattttgagtgc	CRISPR spacer
tcctaaatcaattaatttaatattttgagatt	Protospacer
.  *  ** ********** *********  .

104. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214943 (Mycoplasma orale strain NCTC10112 plasmid 4) position: , mismatch: 10, identity: 0.688

caattcataaattaatttactattttgagtgc	CRISPR spacer
gttttcataaattaatgtactgttttcatatt	Protospacer
   ************* ****.**** *   .

105. spacer 6.8|4417561|32|NZ_CP011018|CRISPRCasFinder,CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

gagacggaaatcgcggttgataacgctgatat	CRISPR spacer
ttgacggaactcgcggatgataacggaagcgc	Protospacer
  ******* ****** ********  .....

106. spacer 7.14|4444874|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MF417930 (Uncultured Caudovirales phage clone 3S_1, partial genome) position: , mismatch: 11, identity: 0.656

acagtgaaatatattgggataacataaagtcg	CRISPR spacer
gtgagaaaatatattgggaaaaaataaaggat	Protospacer
.... .************* ** ******

107. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MT074146 (Bacteroides phage SJC03, complete genome) position: , mismatch: 11, identity: 0.656

caattcataaattaatttactattttgagtgc	CRISPR spacer
agttttataaatcaatttactattttttaatt	Protospacer
 . **.******.*************  .  .

108. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MT074139 (Bacteroides phage DAC19, complete genome) position: , mismatch: 11, identity: 0.656

caattcataaattaatttactattttgagtgc	CRISPR spacer
agttttataaatcaatttactattttttaatt	Protospacer
 . **.******.*************  .  .

109. spacer 7.19|4445180|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to MT074140 (Bacteroides phage DAC20, complete genome) position: , mismatch: 11, identity: 0.656

caattcataaattaatttactattttgagtgc	CRISPR spacer
agttttataaatcaatttactattttttaatt	Protospacer
 . **.******.*************  .  .

110. spacer 7.22|4445363|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 11, identity: 0.656

gcaatgctcgtacgccgtctcactccgcgtga	CRISPR spacer
agtgggctcgtacgccttcacactccgctcct	Protospacer
.  . *********** ** ******** .

111. spacer 7.22|4445363|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 11, identity: 0.656

gcaatgctcgtacgccgtctcactccgcgtga	CRISPR spacer
agtgggctcgtacgccttcacactccgctcct	Protospacer
.  . *********** ** ******** .

112. spacer 7.25|4445546|32|NZ_CP011018|PILER-CR,CRISPRCasFinder,CRT matches to NC_009760 (Bacillus phage 0305phi8-36, complete genome) position: , mismatch: 11, identity: 0.656

tcggtggctggattgaaaaagaagataatctg	CRISPR spacer
cgctcatctcgattgaagaagaagataatcaa	Protospacer
.   .. ** *******.************ .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

222473 : 231915

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569329.1\|222473_223400_+	glycine betaine ABC transporter ATP binding protein YehX	F2Y1V5	Organic_Lake_phycodnavirus	2.0e-08	26.8
WP_000783120.1\|223404_224136_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216961.1\|224116_224224_-	protein YohO	NA	NA	NA	NA
WP_001240401.1\|224283_225015_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
WP_001295431.1\|225236_226922_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_000598641.1\|226918_227638_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295430.1\|227684_228155_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_001295429.1\|228195_228657_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001349936.1\|228781_230782_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.6
WP_001292769.1\|230778_231915_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	3.2e-162	97.4

DBSCAN-SWA_2

288286 : 298985

Enterobacteria_phage(75.0%)

lysis,tail,integrase

attL 284114:284128|attR 308226:308240

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
284114:284128	attL	NA	NA	NA	NA
WP_039264507.1\|288286_289360_-\|integrase	tyrosine-type recombinase/integrase	K7PHK0	Enterobacteria_phage	3.9e-194	96.6
WP_039264506.1\|289337_289556_-	excisionase	Q77WA4	Escherichia_phage	2.4e-34	98.6
WP_039264505.1\|290005_290704_-	DUF1311 domain-containing protein	J9Q6K3	Salmonella_phage	3.9e-102	83.2
WP_039264504.1\|290834_291002_-	DUF2737 family protein	Q716F2	Shigella_phage	1.8e-21	92.7
WP_024215524.1\|290998_291280_-	hypothetical protein	K7P7M4	Enterobacteria_phage	3.3e-44	98.9
WP_024239663.1\|291296_291611_-	hypothetical protein	K7PLT4	Enterobacteria_phage	5.9e-50	99.0
WP_000041317.1\|291622_292105_-	siphovirus Gp157 family protein	K7P6T5	Enterobacteria_phage	1.4e-79	98.8
WP_039264503.1\|292770_293214_+\|lysis	lysis protein	M1FJ79	Enterobacteria_phage	2.4e-73	96.6
WP_039264502.1\|293252_293627_+	hypothetical protein	M1FPD9	Enterobacteria_phage	4.6e-49	81.5
WP_046201413.1\|294251_294986_+	Ail/Lom family outer membrane beta-barrel protein	A0A0K2FIG2	Enterobacteria_phage	1.7e-87	94.4
WP_071885001.1\|295050_298401_+	short-chain fatty acid transporter	X2KTY7	Enterobacteria_phage	1.8e-11	35.5
WP_039264499.1\|298400_298985_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	7.0e-105	96.4
308226:308240	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1019358 : 1055838

Enterobacteria_phage(36.67%)

lysis,tail,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046201463.1\|1019358_1020492_+	porin OmpN	Q1MVN1	Enterobacteria_phage	5.4e-117	58.5
WP_001082294.1\|1020632_1021067_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.0e-28	52.8
WP_120795384.1\|1021843_1021957_+	Rac prophage; protein YnaM	A0A1C9IHU6	Salmonella_phage	8.4e-07	80.6
WP_000836772.1\|1022025_1022259_+	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	4.1e-32	87.0
WP_000086519.1\|1022575_1023166_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	2.8e-24	38.8
WP_000885599.1\|1023263_1023839_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	9.1e-105	96.9
WP_071886251.1\|1023838_1027369_-	short-chain fatty acid transporter	X2KTY7	Enterobacteria_phage	1.9e-11	35.5
WP_001233133.1\|1027433_1028033_-	Ail/Lom family outer membrane beta-barrel protein	A5LH44	Enterobacteria_phage	1.6e-107	95.0
WP_046201464.1\|1028100_1031580_-	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	90.4
WP_000090943.1\|1031640_1032243_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	4.0e-87	84.7
WP_001349612.1\|1032179_1032923_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	8.9e-145	96.3
WP_001152432.1\|1032928_1033627_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.1e-125	93.5
WP_000024051.1\|1033626_1033965_-\|tail	phage tail protein	H6WZM2	Escherichia_phage	4.0e-28	50.0
WP_000840620.1\|1033957_1037191_-\|tail	phage tail tape measure protein	A0A2H4J9A1	uncultured_Caudovirales_phage	1.3e-112	34.7
WP_012565075.1\|1037664_1038024_-	hypothetical protein	NA	NA	NA	NA
WP_000094292.1\|1038174_1039137_-	hypothetical protein	A0A059VG08	Pseudomonas_phage	4.5e-56	39.2
WP_000144678.1\|1039163_1039556_-	hypothetical protein	NA	NA	NA	NA
WP_001029815.1\|1039552_1039933_-	hypothetical protein	A0A059VF88	Pseudomonas_phage	1.1e-18	44.4
WP_000524260.1\|1039933_1040317_-	hypothetical protein	A0A0P0I456	Acinetobacter_phage	2.2e-14	39.4
WP_000634214.1\|1040316_1040712_-	hypothetical protein	NA	NA	NA	NA
WP_000918490.1\|1040934_1042074_-	hypothetical protein	G8C7P7	Escherichia_phage	1.7e-158	74.7
WP_000770036.1\|1042172_1042937_-	hypothetical protein	G8C7P6	Escherichia_phage	6.6e-87	66.5
WP_001317036.1\|1043041_1044154_-	hypothetical protein	I6PD76	Cronobacter_phage	6.0e-113	54.8
WP_000763708.1\|1044137_1045544_-	DUF4055 domain-containing protein	G8C7P4	Escherichia_phage	6.7e-186	68.8
WP_000625347.1\|1045546_1046848_-\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	8.0e-149	59.8
WP_000089446.1\|1046828_1047923_-	hypothetical protein	A0A0U2RXW9	Escherichia_phage	4.5e-113	80.2
WP_000126788.1\|1047926_1048136_-	hypothetical protein	NA	NA	NA	NA
WP_001204033.1\|1048113_1049046_-	hypothetical protein	A0A1B1INP7	uncultured_Mediterranean_phage	4.2e-83	54.5
WP_001291092.1\|1049038_1049833_-	ParB N-terminal domain-containing protein	R4TG31	Halovirus	7.5e-49	40.7
WP_046201465.1\|1049970_1051428_-	potassium transporter TrkG	NA	NA	NA	NA
WP_001228688.1\|1051624_1051810_-\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	3.6e-15	96.5
WP_001135310.1\|1052026_1052524_-	lysozyme RrrD	M1FJA0	Enterobacteria_phage	9.3e-90	96.4
WP_000839565.1\|1052523_1052739_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	1.3e-32	94.4
WP_001348108.1\|1052990_1053365_-	hypothetical protein	NA	NA	NA	NA
WP_000506936.1\|1053536_1053965_-	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_000640162.1\|1055008_1055551_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	4.9e-76	75.7
WP_000247763.1\|1055547_1055838_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.7e-46	87.5

DBSCAN-SWA_4

1062565 : 1080864

Escherichia_phage(66.67%)

tRNA,integrase

attL 1063902:1063915|attR 1078287:1078300

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001676522.1\|1062565_1064563_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	3.3e-21	26.2
1063902:1063915	attL	NA	NA	NA	NA
WP_001151151.1\|1064903_1065326_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	4.8e-63	88.5
WP_001262393.1\|1065366_1066437_-	hypothetical protein	A0A088CD36	Shigella_phage	4.2e-63	65.2
WP_000693853.1\|1066508_1066934_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001072337.1\|1066930_1067185_-	hypothetical protein	A0A2I6PIE5	Escherichia_phage	2.8e-18	60.3
WP_000233320.1\|1067264_1067684_+	helix-turn-helix domain-containing protein	A0A2I6PIE7	Escherichia_phage	4.2e-19	47.5
WP_001169151.1\|1068115_1068271_+	YdaF family protein	M4QQ57	Salicola_phage	6.1e-08	55.3
WP_001312793.1\|1068267_1068756_-	superinfection exclusion protein B	NA	NA	NA	NA
WP_000560225.1\|1069197_1069419_+	killing protein KilR	A0A0U2RTC4	Escherichia_phage	4.9e-35	97.3
WP_001352098.1\|1069418_1069589_+	conserved protein, Rac prophage	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
WP_000632297.1\|1069663_1069939_+	protein RacC	A0A0U2QW85	Escherichia_phage	1.4e-42	96.7
WP_046201466.1\|1070040_1072641_+	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	2.8e-246	63.4
WP_000166319.1\|1072633_1073443_+	recombination protein RecT	A0A1P8DTF2	Proteus_phage	8.8e-106	71.5
WP_001317028.1\|1073499_1073694_+	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	5.8e-32	96.9
WP_000276809.1\|1073686_1073896_+	double-strand break reduction protein RcbA	A0A0U2QL97	Escherichia_phage	6.1e-27	98.4
WP_000079604.1\|1073974_1074190_+	excisionase XisR	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
WP_000040852.1\|1074191_1075427_+\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	5.5e-240	98.8
WP_001153728.1\|1075478_1076414_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	1.0e-145	98.4
WP_000123739.1\|1076542_1077916_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
WP_000387388.1\|1078393_1079377_-	zinc transporter ZntB	NA	NA	NA	NA
1078287:1078300	attR	NA	NA	NA	NA
WP_000628065.1\|1079631_1080864_+	diguanylate cyclase DgcM	A0A127AWB9	Bacillus_phage	3.1e-17	39.5

DBSCAN-SWA_5

1273496 : 1332437

Escherichia_phage(38.78%)

tail,capsid,integrase,terminase,tRNA,holin,portal,head

attL 1284246:1284263|attR 1340960:1340977

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001297484.1\|1273496_1274603_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_001297479.1\|1274638_1275280_+	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_000423729.1\|1275283_1276654_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
WP_001265481.1\|1276821_1277493_+	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000735412.1\|1277492_1278953_+	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_001295435.1\|1279028_1280150_+	[50S ribosomal protein L16]-arginine 3-hydroxylase	NA	NA	NA	NA
WP_038994720.1\|1280295_1281525_-	peptidase T	NA	NA	NA	NA
WP_000531594.1\|1281774_1282911_+	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	5.5e-29	39.8
WP_000799399.1\|1282894_1283758_+	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_077781611.1\|1283922_1284252_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
1284246:1284263	attL	NA	NA	NA	NA
WP_034172969.1\|1284416_1285091_-	DUF4376 domain-containing protein	S5MBX6	Escherichia_phage	2.1e-97	77.1
WP_034172970.1\|1285087_1285312_-\|tail	tail fiber assembly protein	NA	NA	NA	NA
WP_046201470.1\|1285321_1286728_-\|tail	tail protein	S5MDN9	Escherichia_phage	1.4e-103	74.1
WP_046201471.1\|1286796_1286907_-	Hok/Gef family protein	S5M7Q0	Escherichia_phage	1.2e-10	94.1
WP_046201472.1\|1287103_1290580_-	host specificity protein J	Q6H9T2	Enterobacteria_phage	0.0e+00	87.4
WP_046201473.1\|1290821_1291460_-\|tail	tail assembly protein	S5MDP1	Escherichia_phage	2.1e-94	97.8
WP_034173014.1\|1291357_1292101_-\|tail	phage tail protein	S5MQI8	Escherichia_phage	4.0e-145	95.1
WP_034172975.1\|1292106_1292805_-\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	1.3e-118	88.8
WP_034172976.1\|1293010_1294174_-	porin OmpC	Q1MVN1	Enterobacteria_phage	4.2e-141	66.9
WP_034172977.1\|1294399_1294729_-\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	3.8e-47	80.7
WP_046201474.1\|1294725_1297308_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	84.2
WP_049590271.1\|1297288_1297702_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	8.4e-44	86.9
WP_034172979.1\|1297728_1298160_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.5e-43	69.4
WP_034172980.1\|1298179_1298929_-\|tail	phage tail protein	S5M7Q5	Escherichia_phage	1.3e-130	94.8
WP_034172981.1\|1298936_1299332_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	5.7e-58	80.9
WP_046201475.1\|1299328_1299907_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	3.3e-70	88.0
WP_034172983.1\|1299921_1300275_-\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	1.9e-41	70.1
WP_046201476.1\|1300267_1300651_-	DNA-packaging protein FI	NA	NA	NA	NA
WP_034172985.1\|1300702_1301731_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	3.9e-114	61.9
WP_034172986.1\|1301788_1302136_-\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	4.4e-22	57.0
WP_034172987.1\|1302172_1303678_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	4.3e-98	53.4
WP_034172988.1\|1303667_1305260_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	3.2e-184	60.7
WP_046201477.1\|1305256_1305463_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	8.7e-10	53.8
WP_034172989.1\|1305446_1307375_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.1e-263	66.7
WP_034172990.1\|1307346_1307856_-\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.5e-13	34.5
WP_032317909.1\|1308250_1308445_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.4e-27	95.3
WP_139108877.1\|1308577_1308763_+	hypothetical protein	NA	NA	NA	NA
WP_046201478.1\|1308810_1309353_+	cytochrome b	A0A0U2QLA7	Escherichia_phage	1.6e-26	55.6
WP_034172993.1\|1309427_1309934_-	DUF2514 domain-containing protein	NA	NA	NA	NA
WP_034172994.1\|1309930_1310464_-	lysozyme	Q6H9V6	Enterobacteria_phage	1.9e-93	89.8
WP_139108876.1\|1310623_1310896_+	hypothetical protein	NA	NA	NA	NA
WP_046201480.1\|1311151_1311367_-\|holin	holin	Q9ZWW2	Enterobacteria_phage	2.6e-33	98.6
WP_034172997.1\|1311444_1311750_-	DUF826 domain-containing protein	NA	NA	NA	NA
WP_052232680.1\|1311775_1311952_-	DUF1378 family protein	Q5MBW3	Stx1-converting_phage	4.4e-10	60.4
WP_046201481.1\|1312114_1314049_-	DUF1737 domain-containing protein	A0A0P0ZBH7	Stx2-converting_phage	1.9e-263	69.9
WP_034172999.1\|1316187_1317246_-	site-specific DNA-methyltransferase	A0A0N7KZF8	Stx2-converting_phage	1.6e-195	92.6
WP_046201482.1\|1317395_1317593_-	hypothetical protein	S5MQK8	Escherichia_phage	2.3e-28	98.5
WP_034173000.1\|1317819_1318641_-	antitermination protein	K7P7B9	Enterobacteria_phage	4.6e-78	58.2
WP_046201483.1\|1318637_1318874_-	RusA family crossover junction endodeoxyribonuclease	A5VW85	Enterobacteria_phage	5.5e-16	41.6
WP_046201484.1\|1318874_1319933_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	3.1e-90	48.0
WP_046201693.1\|1319934_1320204_-	hypothetical protein	A0A077KB22	Edwardsiella_phage	1.7e-05	38.7
WP_046201485.1\|1320378_1320591_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.1e-26	92.9
WP_072134538.1\|1320779_1320884_-	hypothetical protein	NA	NA	NA	NA
WP_072134537.1\|1321932_1322346_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	1.7e-57	97.5
WP_046201488.1\|1322346_1322769_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	6.7e-65	91.4
WP_046201489.1\|1322784_1323555_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	9.6e-94	73.0
WP_046201490.1\|1323583_1324321_-	ATP-binding protein	A0A088CBP4	Shigella_phage	8.9e-113	83.1
WP_046201696.1\|1324327_1325290_-	DNA-binding protein	U5P0A0	Shigella_phage	5.8e-72	53.0
WP_046201491.1\|1325312_1325738_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000391950.1\|1325721_1326003_-	hypothetical protein	K7PHA1	Enterobacteria_phage	6.5e-24	72.6
WP_000362155.1\|1326103_1326523_+	hypothetical protein	K7PK07	Enterobacteria_phage	8.8e-25	65.1
WP_053099141.1\|1326790_1326943_+	DUF1391 family protein	M4QQ57	Salicola_phage	5.1e-07	53.2
WP_001541619.1\|1328095_1328284_+	hypothetical protein	NA	NA	NA	NA
WP_046201493.1\|1328280_1328472_+	DUF1482 family protein	NA	NA	NA	NA
WP_046201494.1\|1328562_1331019_+	exonuclease	V5UQJ3	Shigella_phage	5.8e-108	44.6
WP_046201495.1\|1331080_1331350_+	excisionase	NA	NA	NA	NA
WP_046201496.1\|1331318_1332437_+\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	4.1e-85	44.7
1340960:1340977	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1565419 : 1653600

Salmonella_phage(56.45%)

lysis,tail,capsid,integrase,terminase,protease,tRNA,plate,portal,head

attL 1587698:1587711|attR 1654063:1654076

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000886683.1\|1565419_1566712_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.5e-94	48.2
WP_000067755.1\|1566802_1568146_-	replication-associated recombination protein RarA	G3MBE0	Bacillus_virus	2.1e-80	40.8
WP_001295343.1\|1568156_1568768_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_000077063.1\|1568922_1573029_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.2e-86	48.7
WP_000228473.1\|1573163_1573658_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_000537418.1\|1574202_1575168_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	8.5e-63	44.6
WP_001043587.1\|1575290_1577057_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	4.1e-23	24.3
WP_001202188.1\|1577057_1578779_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	W8CYL7	Bacillus_phage	1.9e-20	25.2
WP_001241678.1\|1578820_1579525_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|1579809_1580028_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_000934041.1\|1580950_1583227_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.9e-166	42.5
WP_000520781.1\|1583257_1583578_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.6e-13	44.4
WP_000410785.1\|1583900_1584125_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	2.3e-16	61.2
WP_000188180.1\|1584197_1586144_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.1e-37	40.1
WP_032215246.1\|1586140_1587256_-	macrolide transporter subunit MacA	NA	NA	NA	NA
WP_001355621.1\|1587406_1588363_+	DUF535 domain-containing protein	NA	NA	NA	NA
1587698:1587711	attL	NA	NA	NA	NA
WP_000599820.1\|1588359_1590018_-	ATP-dependent endonuclease	NA	NA	NA	NA
WP_001298299.1\|1590443_1591139_+	aquaporin Z	NA	NA	NA	NA
WP_000491127.1\|1591634_1592534_+	L-lysine exporter LysO	NA	NA	NA	NA
WP_000458817.1\|1592677_1594330_+	hydroxylamine reductase	NA	NA	NA	NA
WP_000178677.1\|1594341_1595310_+	NADH oxidoreductase	NA	NA	NA	NA
WP_000815362.1\|1595442_1597161_+	ubiquinone-dependent pyruvate dehydrogenase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	5.2e-31	24.0
WP_000566372.1\|1597197_1598199_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_001136554.1\|1598209_1599640_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_001338420.1\|1599738_1600752_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_001255144.1\|1600748_1601579_-	N-acetylmuramoyl-L-alanine amidase AmiD	A0A1B0UZW5	Roseobacter_phage	5.7e-07	30.0
WP_001160737.1\|1601575_1601899_-	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_001270740.1\|1602024_1602540_+	lipoprotein	NA	NA	NA	NA
WP_000027205.1\|1602757_1603486_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	6.0e-29	36.7
WP_000756569.1\|1603503_1604235_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001001691.1\|1604241_1604958_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_000464491.1\|1604957_1605626_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_001295905.1\|1605917_1606649_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001149734.1\|1606823_1607951_-	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A1X9I6F4	Streptococcus_phage	4.6e-28	27.3
WP_000389260.1\|1607991_1608480_-	YbjO family protein	NA	NA	NA	NA
WP_001061657.1\|1608539_1609385_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_000105438.1\|1609381_1610335_-	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_000996024.1\|1610344_1611478_-	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	5.0e-30	34.4
WP_000126072.1\|1611572_1612685_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_000203025.1\|1613036_1613513_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_000684321.1\|1613600_1614503_-	30S ribosomal protein S6--L-glutamate ligase	I3ULC9	Synechococcus_phage	2.6e-37	34.4
WP_001402143.1\|1614563_1615286_-	nitroreductase NfsA	NA	NA	NA	NA
WP_001201560.1\|1615269_1615557_-	DUF1418 family protein	NA	NA	NA	NA
WP_001195240.1\|1615716_1615974_+	glutaredoxin 1	A0A2I7SAE2	Vibrio_phage	8.6e-23	61.9
WP_000681108.1\|1616003_1616381_-	hypothetical protein	NA	NA	NA	NA
WP_001024876.1\|1616650_1618336_+	aspartate:alanine antiporter	NA	NA	NA	NA
WP_000972391.1\|1618571_1618790_-	transcriptional activator Ogr/delta	Q53ZE7	Salmonella_virus	7.5e-20	69.0
WP_046201500.1\|1618880_1619981_-	phage late control D family protein	E5G6Q3	Salmonella_phage	1.7e-176	85.5
WP_000980396.1\|1619977_1620463_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	2.2e-67	81.2
WP_046201501.1\|1620459_1623537_-\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	0.0e+00	63.4
WP_000763311.1\|1623529_1623649_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.8e-13	87.2
WP_001281013.1\|1623663_1623966_-\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	7.0e-40	89.0
WP_001504081.1\|1624020_1624536_-\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	4.8e-89	94.7
WP_001726272.1\|1624545_1625718_-\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.6e-204	90.5
WP_000905033.1\|1625859_1626426_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	3.8e-87	86.8
WP_071886254.1\|1626453_1626843_+	hypothetical protein	A0A0F7LBW5	Escherichia_phage	2.8e-09	70.0
WP_046201503.1\|1626844_1627288_+\|tail	tail fiber assembly protein	A0A0F7LDZ0	Escherichia_phage	9.2e-57	71.4
WP_000367939.1\|1627259_1627862_-\|tail	tail fiber assembly protein	M1SV83	Escherichia_phage	7.8e-99	90.0
WP_046201504.1\|1627861_1629403_-\|tail	phage tail protein	M1TAS6	Escherichia_phage	5.5e-197	71.3
WP_001086820.1\|1629399_1630005_-\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	5.2e-111	92.5
WP_000268301.1\|1629997_1630906_-\|plate	baseplate assembly protein	A0A1S6KZY6	Salmonella_phage	4.1e-144	91.1
WP_000177400.1\|1630892_1631252_-\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	1.2e-51	86.6
WP_042096888.1\|1631248_1631827_-\|plate	phage baseplate assembly protein V	A0A1S6KZX7	Salmonella_phage	1.9e-94	87.0
WP_000829119.1\|1631895_1632342_-	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.3e-63	86.3
WP_001039933.1\|1632334_1632766_-\|tail	phage tail protein	E5G6N3	Salmonella_phage	2.2e-71	93.0
WP_046201505.1\|1632861_1633290_-\|lysis	LysB family phage lysis regulatory protein	E5G6N2	Salmonella_phage	1.5e-48	78.7
WP_032200197.1\|1633286_1633664_-	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	5.1e-16	40.0
WP_046201506.1\|1633665_1634178_-	lysozyme	E5G6N1	Salmonella_phage	5.8e-87	91.7
WP_000171568.1\|1634158_1634374_-	hypothetical protein	E5G6N0	Salmonella_phage	1.8e-26	80.3
WP_000868170.1\|1634377_1634581_-\|tail	tail protein X	E5G6M9	Salmonella_phage	8.8e-31	91.0
WP_000673524.1\|1634580_1635045_-\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	1.4e-76	89.0
WP_000059206.1\|1635140_1635791_-\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	2.5e-111	95.4
WP_000742510.1\|1635794_1636853_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	3.8e-181	93.4
WP_000216237.1\|1636869_1637703_-\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	2.8e-123	91.0
WP_001098431.1\|1637845_1639612_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.7
WP_046201507.1\|1639611_1640640_+\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	8.4e-170	87.6
WP_001518830.1\|1640686_1642351_-	hypothetical protein	X2KLG0	Campylobacter_phage	9.9e-11	25.3
WP_000207842.1\|1642645_1643365_-	hypothetical protein	NA	NA	NA	NA
WP_001217575.1\|1643487_1643721_-	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_001154434.1\|1643731_1643920_-	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_046201508.1\|1644073_1646488_-	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	95.5
WP_000104133.1\|1646484_1647342_-	DNA adenine methylase	E5G6L8	Salmonella_phage	2.1e-158	96.1
WP_000752613.1\|1647338_1647566_-	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	2.7e-36	100.0
WP_001244228.1\|1647565_1647799_-	DUF2732 family protein	E5G6L6	Salmonella_phage	6.4e-33	98.7
WP_000996717.1\|1647866_1648208_-	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	1.7e-55	98.2
WP_097156329.1\|1648325_1648592_-	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	1.1e-15	83.3
WP_000166365.1\|1648785_1649244_+	hypothetical protein	NA	NA	NA	NA
WP_001350183.1\|1649191_1649425_-	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	5.2e-11	86.1
WP_000460900.1\|1649432_1649942_-	phage regulatory CII family protein	E5G6L3	Salmonella_phage	2.9e-86	98.2
WP_000188450.1\|1650006_1650210_-	hypothetical protein	NA	NA	NA	NA
WP_001350184.1\|1650355_1650925_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	3.2e-38	41.9
WP_001350185.1\|1650940_1651123_+	hypothetical protein	A0A0R6PI25	Moraxella_phage	8.5e-09	55.9
WP_000102108.1\|1651136_1652468_+	NTPase	R9TRQ8	Vibrio_phage	3.2e-20	27.1
WP_000290937.1\|1652547_1653600_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	3.6e-107	57.3
1654063:1654076	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1951503 : 2007442

Enterobacteria_phage(66.07%)

lysis,tail,capsid,integrase,terminase,protease,tRNA,portal,head

attL 1951035:1951081|attR 1997236:1997282

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1951035:1951081	attL	NA	NA	NA	NA
WP_001201825.1\|1951503_1952457_+\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_032230883.1\|1952643_1954128_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_001547145.1\|1954311_1954617_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.8e-12	76.5
WP_000239881.1\|1954673_1955342_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_046201517.1\|1955396_1955981_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.0e-103	94.8
WP_071886259.1\|1955980_1959052_-\|tail	phage tail protein	U5N099	Enterobacteria_phage	1.9e-68	82.1
WP_046201519.1\|1959116_1959716_-	Ail/Lom family outer membrane beta-barrel protein	H6WZM8	Escherichia_phage	6.5e-106	95.0
WP_046201520.1\|1959783_1963263_-	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	90.5
WP_000090847.1\|1963323_1963926_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	1.8e-87	85.1
WP_047675718.1\|1963862_1964606_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.4e-145	95.5
WP_001499538.1\|1964611_1965310_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	3.3e-133	99.6
WP_000847379.1\|1965309_1965639_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	9.6e-59	100.0
WP_046201522.1\|1965635_1968197_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	98.7
WP_000459457.1\|1968189_1968624_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000479142.1\|1968605_1969028_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	1.1e-70	96.4
WP_001358372.1\|1969043_1969784_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	1.4e-129	98.0
WP_000683105.1\|1969791_1970187_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.0e-70	100.0
WP_046201523.1\|1970183_1970762_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	4.6e-80	99.5
WP_000752979.1\|1970773_1971127_-\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	2.0e-62	100.0
WP_021499141.1\|1971138_1971537_-	DNA packaging FI family protein	A0A0K2FIR1	Enterobacteria_phage	3.5e-63	98.5
WP_000063280.1\|1971578_1972604_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	7.1e-193	100.0
WP_001358225.1\|1972659_1972992_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.5e-54	98.2
WP_000123298.1\|1973001_1974321_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	6.2e-234	98.6
WP_042110164.1\|1974301_1975903_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	9.4e-309	98.7
WP_000198149.1\|1975899_1976106_-\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_046201524.1\|1976102_1978028_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.4
WP_046201525.1\|1978002_1978548_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	4.0e-94	98.3
WP_001307652.1\|1978936_1979131_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.7e-27	96.8
WP_000738423.1\|1979490_1979784_+	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	2.0e-44	91.8
WP_122985311.1\|1979874_1980057_-\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_001135254.1\|1980273_1980771_-	lysozyme	M1FJA0	Enterobacteria_phage	1.6e-86	94.5
WP_000839596.1\|1980770_1980986_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_000737263.1\|1981559_1982642_+	porin OmpD	Q1MVN1	Enterobacteria_phage	4.4e-161	78.7
WP_001204774.1\|1982830_1983214_-	antitermination protein QuuD	A0A088CD47	Shigella_phage	5.2e-56	83.3
WP_032145910.1\|1983299_1983440_-	YlcG family protein	K7PHH3	Enterobacteria_phage	6.5e-09	69.8
WP_001099516.1\|1983436_1983799_-	RusA family crossover junction endodeoxyribonuclease	K7PM48	Enterobacteria_phage	2.3e-58	94.0
WP_000774490.1\|1983795_1984086_-	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.5e-47	94.8
WP_000224916.1\|1984078_1984249_-	hypothetical protein	K7P7K0	Enterobacteria_phage	1.5e-12	67.9
WP_046201527.1\|1984248_1984704_-	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	7.0e-60	67.5
WP_072106870.1\|1984700_1984802_-	hypothetical protein	NA	NA	NA	NA
WP_000622057.1\|1984893_1985376_-	hypothetical protein	NA	NA	NA	NA
WP_000371307.1\|1985632_1986385_-	DUF4145 domain-containing protein	A0A1S6L018	Salmonella_phage	3.9e-31	36.5
WP_000145946.1\|1986673_1986967_-	winged helix-turn-helix transcriptional regulator	A0A0P0ZCJ0	Stx2-converting_phage	3.7e-38	84.9
WP_001361480.1\|1986963_1987665_-	replication P family protein	M1FJ72	Enterobacteria_phage	1.4e-128	98.7
WP_001361484.1\|1987661_1988591_-	replication protein	A0A0M5M7Y1	Salmonella_phage	4.0e-110	63.8
WP_001182887.1\|1988677_1989217_-	hypothetical protein	K7PJT7	Enterobacteria_phage	2.6e-61	67.0
WP_000184665.1\|1989247_1989475_-	helix-turn-helix domain-containing protein	Q76H55	Enterobacteria_phage	3.8e-22	69.0
WP_001295669.1\|1989585_1990278_+	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	1.5e-109	86.1
WP_000741702.1\|1990407_1991547_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_000581650.1\|1991543_1992056_+	DUF4411 family protein	NA	NA	NA	NA
WP_000233576.1\|1992534_1992741_+	phage encoded cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
WP_000995430.1\|1992817_1993114_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	4.7e-49	99.0
WP_000100847.1\|1993119_1993905_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_046201528.1\|1993901_1994582_+	YqaJ viral recombinase family protein	Q6H9Z0	Enterobacteria_phage	3.9e-131	98.2
WP_000682299.1\|1994578_1994761_+	DUF1317 domain-containing protein	Q6H9Z1	Enterobacteria_phage	3.7e-28	98.3
WP_000548513.1\|1994733_1994925_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	4.0e-25	95.2
WP_001386642.1\|1994935_1995217_+	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	5.5e-47	98.9
WP_000763387.1\|1995315_1995534_+	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	1.7e-35	98.6
WP_000488407.1\|1995581_1995860_+	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.9e-48	97.8
WP_000446901.1\|1995831_1996203_+	helix-turn-helix domain-containing protein	M1FJ59	Enterobacteria_phage	5.5e-47	82.8
WP_042109860.1\|1996058_1997222_+\|integrase	site-specific integrase	A0A088CD23	Shigella_phage	1.7e-198	86.0
WP_000805428.1\|1997556_1998189_+	fimbria biosynthesis transcriptional regulator FimZ	NA	NA	NA	NA
1997236:1997282	attR	NA	NA	NA	NA
WP_001250423.1\|1998191_1998707_-	fimbria assembly protein	NA	NA	NA	NA
WP_000691050.1\|1998717_1999725_-	type 1 fimbrin D-mannose specific adhesin FimH	NA	NA	NA	NA
WP_000988366.1\|2002376_2003069_-	type 1 fimbria chaperone FimC	NA	NA	NA	NA
WP_000776555.1\|2003288_2003831_-	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
WP_000729154.1\|2004311_2005178_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
WP_000190288.1\|2005179_2005392_+	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_001143543.1\|2005499_2006021_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_000912345.1\|2006056_2007442_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.9e-45	34.8

DBSCAN-SWA_8

2344055 : 2376204

Vibrio_phage(100.0%)

plate,transposase,integrase

attL 2336617:2336676|attR 2379972:2380048

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2336617:2336676	attL	NA	NA	NA	NA
WP_000420795.1\|2344055_2345192_-\|transposase	ISAs1-like element ISEc1 family transposase	NA	NA	NA	NA
WP_001199686.1\|2348008_2348440_-	DUF1795 domain-containing protein	NA	NA	NA	NA
WP_032141711.1\|2348467_2350687_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_100224276.1\|2350711_2351059_-	hypothetical protein	NA	NA	NA	NA
WP_001402126.1\|2351079_2351646_-	hypothetical protein	NA	NA	NA	NA
WP_024170797.1\|2351862_2352639_-	DUF2094 domain-containing protein	NA	NA	NA	NA
WP_032217617.1\|2352638_2356505_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_000522897.1\|2356504_2356750_-	hypothetical protein	NA	NA	NA	NA
WP_001060994.1\|2356800_2357475_-	hypothetical protein	NA	NA	NA	NA
WP_001402123.1\|2357480_2358797_-	type VI secretion system protein TssL	NA	NA	NA	NA
WP_000118770.1\|2358793_2360137_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_001402122.1\|2360140_2360674_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_000119441.1\|2360741_2361227_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_000871596.1\|2361340_2361712_-	hypothetical protein	NA	NA	NA	NA
WP_000533466.1\|2361708_2362194_-	hypothetical protein	NA	NA	NA	NA
WP_000245849.1\|2362246_2363761_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_000996814.1\|2363785_2364331_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_000144225.1\|2364392_2364683_-	hypothetical protein	NA	NA	NA	NA
WP_001040751.1\|2364685_2365249_-	hypothetical protein	NA	NA	NA	NA
WP_046201555.1\|2365261_2367895_-	type VI secretion system ATPase TssH	A0A2I7SAX5	Vibrio_phage	2.5e-80	32.8
WP_000804010.1\|2368227_2369142_+	type VI secretion system-associated protein TagK	NA	NA	NA	NA
WP_000183810.1\|2369128_2369959_+	hypothetical protein	NA	NA	NA	NA
WP_001276642.1\|2369955_2370450_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000371477.1\|2370465_2372349_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_039264360.1\|2372345_2373341_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_000450225.1\|2373351_2374398_+	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_000985079.1\|2374397_2374673_+	HigA family addiction module antidote protein	NA	NA	NA	NA
WP_001396203.1\|2375838_2376204_+\|integrase	integrase	NA	NA	NA	NA
2379972:2380048	attR	NA	NA	NA	NA

DBSCAN-SWA_9

4229455 : 4306769

Shigella_phage(56.1%)

tail,transposase,integrase,protease,tRNA,plate,head

attL 4299526:4299540|attR 4311203:4311217

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000886095.1\|4229455_4230436_-\|tRNA	tRNA-modifying protein YgfZ	NA	NA	NA	NA
WP_000354046.1\|4230678_4230945_+	FAD assembly factor SdhE	NA	NA	NA	NA
WP_000244772.1\|4230925_4231333_+	membrane protein	NA	NA	NA	NA
WP_001055874.1\|4231372_4231894_-	flavodoxin FldB	NA	NA	NA	NA
WP_000806638.1\|4232005_4232902_+	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	6.7e-30	28.6
WP_000715214.1\|4232926_4233637_+	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	NA	NA	NA	NA
WP_000813215.1\|4233642_4235376_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.2e-60	28.5
WP_001701073.1\|4235466_4236564_+	peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	1.8e-05	39.0
WP_000003068.1\|4236574_4238092_+\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	5.9e-87	36.7
WP_001192814.1\|4238134_4238683_-	isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_120795390.1\|4238737_4238809_+	protein YqfH	NA	NA	NA	NA
WP_001010156.1\|4238805_4238931_-	hypothetical protein	NA	NA	NA	NA
WP_001295374.1\|4238932_4240381_-	urate/proton symporter UacT	Q9KX94	Enterobacteria_phage	7.3e-26	26.8
WP_001355763.1\|4240816_4242736_+	formate-dependent uric acid utilization protein YgfT	NA	NA	NA	NA
WP_000838428.1\|4242735_4243224_+	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_000012163.1\|4243259_4244627_-	guanine/hypoxanthine transporter GhxQ	A0A0R6PHV4	Moraxella_phage	2.1e-160	73.1
WP_001295158.1\|4244662_4245979_-	guanine deaminase	NA	NA	NA	NA
WP_001280215.1\|4245996_4247397_-	xanthine/proton symporter XanQ	H9YQ34	environmental_Halophage	1.7e-19	46.1
WP_000583616.1\|4247561_4250432_-	molybdopterin-dependent oxidoreductase Mo/Fe-S-binding subunit	NA	NA	NA	NA
WP_000572462.1\|4250428_4251208_-	molybdopterin-dependent oxidoreductase FAD-binding subunit	NA	NA	NA	NA
WP_000906276.1\|4251258_4252587_-	putative aminohydrolase SsnA	NA	NA	NA	NA
WP_000502424.1\|4252589_4255688_-	putative selenate reductase subunit YgfK	NA	NA	NA	NA
WP_001272834.1\|4256009_4256588_-	molybdenum cofactor cytidylyltransferase	NA	NA	NA	NA
WP_000835703.1\|4256690_4257461_+	putative selenium-dependent hydroxylase accessory protein YqeC	NA	NA	NA	NA
WP_001020381.1\|4257508_4259134_+	EF2563 family selenium-dependent molybdenum hydroxylase system protein	NA	NA	NA	NA
WP_000037998.1\|4259174_4260107_-	carbamate kinase	NA	NA	NA	NA
WP_001264452.1\|4260154_4261540_-	dihydropyrimidinase	NA	NA	NA	NA
WP_001107125.1\|4261592_4262804_-	YgeY family selenium metabolism-linked hydrolase	NA	NA	NA	NA
WP_000110493.1\|4262861_4264058_-	diaminopropionate ammonia-lyase	NA	NA	NA	NA
WP_001303128.1\|4264115_4265303_-	knotted carbamoyltransferase YgeW	NA	NA	NA	NA
WP_000417808.1\|4265781_4267560_+	sigma-54-dependent transcriptional regulator	NA	NA	NA	NA
WP_001016606.1\|4267599_4268079_-	xanthine dehydrogenase iron sulfur-binding subunit XdhC	NA	NA	NA	NA
WP_000459182.1\|4268075_4268954_-	xanthine dehydrogenase FAD-binding subunit XdhB	NA	NA	NA	NA
WP_046201602.1\|4269501_4270236_-	hypothetical protein	A0A0C4UQZ7	Shigella_phage	2.2e-103	78.2
WP_014334043.1\|4270189_4270390_-	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_046201603.1\|4270653_4270956_+	hypothetical protein	NA	NA	NA	NA
WP_046201604.1\|4271115_4271370_-	DUF826 domain-containing protein	NA	NA	NA	NA
WP_046201605.1\|4271405_4271588_-	DUF1378 family protein	S5MBZ5	Escherichia_phage	5.9e-10	55.0
WP_046201606.1\|4271724_4273803_-	sialate O-acetylesterase	S5MDQ7	Escherichia_phage	4.1e-232	66.8
WP_046201709.1\|4274107_4274629_+\|tail	tail protein	A0A0U2QV64	Escherichia_phage	8.1e-44	47.4
WP_046201607.1\|4274660_4275542_-	hypothetical protein	C9DGQ8	Escherichia_phage	2.8e-28	39.5
WP_046201608.1\|4275541_4276102_-	YmfQ family protein	C9DGQ7	Escherichia_phage	6.6e-44	47.0
WP_046201609.1\|4276092_4277175_-\|plate	baseplate J/gp47 family protein	A0A0C4UQU9	Shigella_phage	2.4e-98	53.5
WP_046201610.1\|4277174_4277612_-	hypothetical protein	A0A0C4UR04	Shigella_phage	4.5e-40	57.6
WP_077787734.1\|4277604_4278219_-\|plate	phage baseplate assembly protein V	A0A0C4UQZ3	Shigella_phage	1.9e-52	51.8
WP_046201612.1\|4278208_4279336_-\|tail	tail protein	C9DGQ3	Escherichia_phage	2.0e-95	48.2
WP_046201613.1\|4279319_4280678_-	multidrug DMT transporter permease	A0A0C4UR32	Shigella_phage	2.2e-53	31.9
WP_046201614.1\|4280664_4282722_-	tape measure protein	A0A0C4UQU8	Shigella_phage	2.9e-76	39.4
WP_046201615.1\|4282849_4283326_-	hypothetical protein	A0A0C4UR03	Shigella_phage	1.6e-22	49.6
WP_046201616.1\|4283340_4283706_-\|tail	phage tail protein	NA	NA	NA	NA
WP_046201617.1\|4283714_4285196_-\|tail	tail protein	A0A0C4UQS0	Shigella_phage	2.2e-134	52.1
WP_046201618.1\|4285195_4285459_-	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_046201619.1\|4285462_4286026_-	DUF1834 family protein	A0A0C4UQU7	Shigella_phage	6.3e-42	47.1
WP_046201620.1\|4286022_4286442_-	gp436 family protein	A0A0C4UR02	Shigella_phage	3.6e-34	55.0
WP_046201621.1\|4286438_4286888_-	hypothetical protein	NA	NA	NA	NA
WP_046201622.1\|4286931_4287879_-\|head	head protein	A0A0C4UQR9	Shigella_phage	2.5e-123	67.2
WP_046201623.1\|4287878_4289012_-\|protease	protease	A0A0C4UQU6	Shigella_phage	1.4e-88	51.6
WP_046201624.1\|4289189_4289663_-	phage virion morphogenesis protein	A0A0C4UR01	Shigella_phage	1.3e-37	53.9
WP_046201625.1\|4289784_4291116_-\|head	phage head morphogenesis protein	A0A0C4UQY9	Shigella_phage	9.9e-155	59.2
WP_046201710.1\|4291099_4292689_-	DUF935 domain-containing protein	A0A0C4UQR8	Shigella_phage	1.6e-167	57.3
WP_046201711.1\|4292688_4294341_-	hypothetical protein	A0A0C4UR29	Shigella_phage	8.9e-230	71.9
WP_000360580.1\|4294400_4294982_-	DUF3486 family protein	A0A0C4UQU5	Shigella_phage	4.2e-49	57.0
WP_001279080.1\|4294984_4295275_-	hypothetical protein	A0A0C4UR00	Shigella_phage	2.1e-25	63.2
WP_033816661.1\|4295271_4295580_-	DUF2730 family protein	NA	NA	NA	NA
WP_046201626.1\|4295560_4295788_-	TraR/DksA family transcriptional regulator	NA	NA	NA	NA
WP_005136374.1\|4295798_4296017_-	hypothetical protein	NA	NA	NA	NA
WP_144405570.1\|4296000_4296429_-	hypothetical protein	NA	NA	NA	NA
WP_046201628.1\|4296463_4296964_-	lysozyme	B6SD29	Bacteriophage	9.2e-29	43.9
WP_000852372.1\|4297035_4297458_-	transcriptional regulator	NA	NA	NA	NA
WP_046201629.1\|4297528_4298038_-	gp16 family protein	A0A0C4UQU3	Shigella_phage	4.8e-25	46.1
WP_046201630.1\|4298034_4298331_-	hypothetical protein	NA	NA	NA	NA
WP_046201631.1\|4298509_4298842_-	hypothetical protein	NA	NA	NA	NA
WP_046201632.1\|4298880_4299066_-	hypothetical protein	NA	NA	NA	NA
WP_046201633.1\|4299062_4299614_-	DNA-binding protein	NA	NA	NA	NA
4299526:4299540	attL	NA	NA	NA	NA
WP_046201634.1\|4299617_4300133_-	hypothetical protein	C9DGM0	Escherichia_phage	4.7e-44	53.0
WP_046201635.1\|4300132_4300666_-	hypothetical protein	A0A0C4UQU2	Shigella_phage	8.8e-62	65.5
WP_046201636.1\|4300669_4301212_-	hypothetical protein	A0A0C4UQZ6	Shigella_phage	1.4e-27	39.4
WP_046201637.1\|4301309_4301840_-	host-nuclease inhibitor protein Gam	C9DGL8	Escherichia_phage	7.2e-48	56.6
WP_046201638.1\|4301851_4302145_-	hypothetical protein	NA	NA	NA	NA
WP_046201639.1\|4302219_4302474_-	hypothetical protein	NA	NA	NA	NA
WP_046201640.1\|4302486_4302708_-	hypothetical protein	NA	NA	NA	NA
WP_046201641.1\|4302710_4303643_-	AAA family ATPase	A0A0C4UQR3	Shigella_phage	2.8e-71	49.0
WP_046201642.1\|4303718_4305806_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2D1GNK9	Pseudomonas_phage	9.7e-165	44.9
WP_001575658.1\|4305808_4306039_-	DNA-binding protein	A0A0C4UQU0	Shigella_phage	1.8e-08	40.8
WP_046201643.1\|4306223_4306769_+	hypothetical protein	A0A2I7S9A5	Vibrio_phage	5.4e-06	35.2
4311203:4311217	attR	NA	NA	NA	NA

DBSCAN-SWA_10

4461962 : 4469102

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001278994.1\|4461962_4462601_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
WP_000590392.1\|4462597_4463860_-	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	1.3e-135	61.4
WP_000847985.1\|4463856_4464765_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_001272549.1\|4464930_4465728_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	5.9e-70	56.3
WP_001141330.1\|4465778_4466435_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	4.3e-50	46.7
WP_001272924.1\|4466540_4469102_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.7e-30	20.6

DBSCAN-SWA_11

4827135 : 4880135

Shigella_phage(53.85%)

tail,transposase,integrase,protease,plate,head

attL 4836172:4836190|attR 4858265:4858283

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000958693.1\|4827135_4828293_-\|integrase	prophage integrase IntS	A5VW56	Enterobacteria_phage	6.5e-219	98.7
WP_000368131.1\|4828604_4829537_-	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	1.2e-167	100.0
WP_000776768.1\|4829830_4830586_+	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_000937833.1\|4830767_4831826_-	hypothetical protein	NA	NA	NA	NA
WP_001296861.1\|4832191_4833532_-	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_000030901.1\|4833903_4834188_+	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_000531954.1\|4834367_4835678_+	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_001583728.1\|4835677_4837822_+	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
4836172:4836190	attL	NA	NA	NA	NA
WP_001195819.1\|4838024_4838510_+	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_000033328.1\|4839184_4839748_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_000185422.1\|4841939_4842581_-	helix-turn-helix transcriptional regulator	A0A1C6ZDG7	Pseudomonas_phage	4.8e-06	43.8
WP_001266279.1\|4842732_4842999_+	transcriptional regulator	M1PVU4	Vibrio_phage	1.4e-07	46.0
WP_046201660.1\|4843009_4845100_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2D1GNK9	Pseudomonas_phage	3.1e-163	46.3
WP_046201641.1\|4845175_4846108_+	AAA family ATPase	A0A0C4UQR3	Shigella_phage	2.8e-71	49.0
WP_046201640.1\|4846110_4846332_+	hypothetical protein	NA	NA	NA	NA
WP_046201639.1\|4846344_4846599_+	hypothetical protein	NA	NA	NA	NA
WP_046201661.1\|4846673_4846967_+	hypothetical protein	NA	NA	NA	NA
WP_001129558.1\|4846978_4847509_+	host-nuclease inhibitor protein Gam	C9DGL8	Escherichia_phage	2.5e-48	57.1
WP_046201662.1\|4847606_4848149_+	hypothetical protein	A0A0C4UQZ6	Shigella_phage	5.8e-29	40.6
WP_046201663.1\|4848152_4848686_+	hypothetical protein	A0A0C4UQU2	Shigella_phage	2.0e-66	67.8
WP_046201634.1\|4848685_4849201_+	hypothetical protein	C9DGM0	Escherichia_phage	4.7e-44	53.0
WP_046201633.1\|4849204_4849756_+	DNA-binding protein	NA	NA	NA	NA
WP_046201664.1\|4849752_4849938_+	hypothetical protein	NA	NA	NA	NA
WP_046201665.1\|4849976_4850309_+	hypothetical protein	NA	NA	NA	NA
WP_046201666.1\|4850301_4850499_+	hypothetical protein	NA	NA	NA	NA
WP_046201630.1\|4850488_4850785_+	hypothetical protein	NA	NA	NA	NA
WP_046201667.1\|4850781_4851291_+	gp16 family protein	A0A0C4UQU3	Shigella_phage	4.8e-25	46.1
WP_000852372.1\|4851361_4851784_+	transcriptional regulator	NA	NA	NA	NA
WP_046201668.1\|4851855_4852356_+	lysozyme	A0A2H4J3P8	uncultured_Caudovirales_phage	1.9e-26	41.4
WP_144405571.1\|4852390_4852819_+	hypothetical protein	NA	NA	NA	NA
WP_005136374.1\|4852802_4853021_+	hypothetical protein	NA	NA	NA	NA
WP_046201670.1\|4853031_4853259_+	TraR/DksA family transcriptional regulator	NA	NA	NA	NA
WP_033816661.1\|4853239_4853548_+	DUF2730 family protein	NA	NA	NA	NA
WP_001279080.1\|4853544_4853835_+	hypothetical protein	A0A0C4UR00	Shigella_phage	2.1e-25	63.2
WP_000360581.1\|4853837_4854419_+	DUF3486 family protein	A0A0C4UQU5	Shigella_phage	1.9e-49	57.0
WP_046201671.1\|4854418_4856083_+	hypothetical protein	A0A0C4UR29	Shigella_phage	2.0e-229	73.0
WP_046201715.1\|4856082_4857672_+	DUF935 domain-containing protein	A0A0C4UQR8	Shigella_phage	5.1e-166	56.3
WP_046201672.1\|4857655_4858987_+\|head	phage head morphogenesis protein	A0A0C4UQY9	Shigella_phage	2.2e-154	59.2
4858265:4858283	attR	NA	NA	NA	NA
WP_000094809.1\|4859108_4859582_+	phage virion morphogenesis protein	A0A0C4UR01	Shigella_phage	4.6e-38	54.6
WP_046201673.1\|4859759_4860884_+\|protease	protease	A0A0C4UQU6	Shigella_phage	5.9e-76	46.8
WP_012908603.1\|4860883_4861831_+\|head	head protein	A0A0C4UQR9	Shigella_phage	7.1e-123	67.2
WP_046201674.1\|4861874_4862282_+	hypothetical protein	NA	NA	NA	NA
WP_046201675.1\|4862278_4862698_+	gp436 family protein	A0A0C4UR02	Shigella_phage	2.3e-33	53.6
WP_046201676.1\|4862694_4863258_+	DUF1834 family protein	A0A0C4UQU7	Shigella_phage	3.1e-41	46.5
WP_000207438.1\|4863261_4863540_+	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_046201677.1\|4863539_4865021_+\|tail	tail protein	A0A0C4UQS0	Shigella_phage	3.3e-135	52.5
WP_000015471.1\|4865029_4865395_+\|tail	phage tail protein	C9DGP8	Escherichia_phage	3.8e-24	50.0
WP_046201678.1\|4865409_4865889_+	hypothetical protein	A0A0C4UR03	Shigella_phage	2.3e-21	49.2
WP_046201679.1\|4866016_4868074_+	tape measure protein	A0A0C4UQU8	Shigella_phage	3.7e-76	38.9
WP_012908610.1\|4868060_4869419_+	DMT family permease	A0A0C4UR32	Shigella_phage	3.4e-49	30.3
WP_046201680.1\|4869402_4870530_+\|tail	tail protein	C9DGQ3	Escherichia_phage	1.2e-95	48.2
WP_073520730.1\|4870519_4871134_+\|plate	phage baseplate assembly protein V	A0A0C4UQZ3	Shigella_phage	1.2e-51	50.8
WP_046201681.1\|4871126_4871564_+	hypothetical protein	A0A0C4UR04	Shigella_phage	5.4e-41	58.3
WP_001146843.1\|4871563_4872646_+\|plate	baseplate J/gp47 family protein	A0A0C4UQU9	Shigella_phage	1.1e-98	53.2
WP_046201682.1\|4872636_4873197_+	YmfQ family protein	C9DGQ7	Escherichia_phage	4.6e-45	48.1
WP_046201683.1\|4873196_4874087_+	hypothetical protein	C9DGQ8	Escherichia_phage	5.6e-37	47.5
WP_046201684.1\|4874138_4874660_+\|tail	tail protein	A0A0U2QV64	Escherichia_phage	7.3e-45	49.1
WP_077787742.1\|4874694_4875060_-\|tail	phage tail protein	A0A0U2SAV1	Escherichia_phage	9.1e-18	61.2
WP_012908617.1\|4875154_4875727_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	1.7e-74	76.9
WP_046201685.1\|4875812_4877861_+	hypothetical protein	S5MDQ7	Escherichia_phage	2.3e-227	63.4
WP_046201686.1\|4877995_4878178_+	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.6e-10	57.9
WP_001114098.1\|4878213_4878468_+	DUF826 domain-containing protein	NA	NA	NA	NA
WP_046201687.1\|4878543_4878744_+	hypothetical protein	NA	NA	NA	NA
WP_032164298.1\|4878928_4879114_+	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_046201688.1\|4879082_4880135_+	DNA cytosine methyltransferase	H9C177	Pectobacterium_phage	4.1e-119	63.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011019

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP011018

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection