CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP009686	Bacillus cereus strain FORC_005 chromosome, complete genome	1 crisprs	cas3,csa3,WYL,c2c9_V-U4,DinG,DEDDh	0	2	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009686_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009686_1

5133171-5133304

Orphan

Consensus_repeat	Method
GTTGATTTCTCTTCTTTTTGAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP009686_1

>merge|NZ_CP009686|1|5133171-5133304|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGGTTCTTCTTTTTTGTCACTAGTTGAACCGCTTGTTGATTTCTCTTCTTTTTGAGACTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTCGTTGACTTCTCTTCTTTTTGAGA

>NZ_CP009686|1|1|5133171-5133304|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGG	TTCTTCTTTTTTGTCACTAGTTGAACCGCTT
GTTGATTTCTCTTCTTTTTGAGA	CTTGTCTTCTGTTTTACTTTCTGGTTTCGTGCTC
GTTGACTTCTCTTCTTTTTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009686.1\|WP_016099316.1\|5127524_5128226_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP009686.1\|WP_016099314.1\|5125524_5126406_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP009686.1\|WP_046393108.1\|5143814_5145677_-\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836
NZ_CP009686.1\|WP_000931959.1\|5130243_5130678_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP009686.1\|WP_046393104.1\|5126652_5127420_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP009686.1\|WP_000672663.1\|5137028_5138048_-\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332
NZ_CP009686.1\|WP_000544012.1\|5132267_5132540_-\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP009686.1\|WP_000393152.1\|5128215_5128962_-\|capsular-polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NZ_CP009686.1\|WP_046393107.1\|5142315_5143818_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP009686.1\|WP_006926555.1\|5134192_5134900_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP009686.1\|WP_000057889.1\|5140354_5140591_-\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP009686.1\|WP_046393105.1\|5134899_5135742_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP009686.1\|WP_000367481.1\|5140793_5142314_-\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP009686.1\|WP_000008901.1\|5132848_5132983_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009686.1\|WP_016099313.1\|5123652_5125464_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP009686.1\|WP_046393106.1\|5135923_5136931_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP009686.1\|WP_002005985.1\|5139598_5140309_-\|YwmB-family-TATA-box-binding-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP009686.1\|WP_000457978.1\|5131105_5132107_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563
NZ_CP009686.1\|WP_000467956.1\|5129220_5129898_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP009686.1\|WP_000411274.1\|5138254_5139559_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486

Protein	Function_ID	Function_description	E-value
NZ_CP009686.1\|WP_016099316.1\|5127524_5128226_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	3.70253e-83
NZ_CP009686.1\|WP_016099314.1\|5125524_5126406_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0
NZ_CP009686.1\|WP_046393108.1\|5143814_5145677_-\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NZ_CP009686.1\|WP_000931959.1\|5130243_5130678_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	5.26499e-95
NZ_CP009686.1\|WP_046393104.1\|5126652_5127420_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	2.65632e-105
NZ_CP009686.1\|WP_000672663.1\|5137028_5138048_-\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	5.80584e-135
NZ_CP009686.1\|WP_000544012.1\|5132267_5132540_-\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.17272e-38
NZ_CP009686.1\|WP_000393152.1\|5128215_5128962_-\|capsular-polysaccharide-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	9.49315e-82
NZ_CP009686.1\|WP_046393107.1\|5142315_5143818_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	1.22741e-177
NZ_CP009686.1\|WP_006926555.1\|5134192_5134900_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	5.40923e-09
NZ_CP009686.1\|WP_000057889.1\|5140354_5140591_-\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	1.23409e-23
NZ_CP009686.1\|WP_046393105.1\|5134899_5135742_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.26661e-88
NZ_CP009686.1\|WP_000367481.1\|5140793_5142314_-\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	4.78994e-150
NZ_CP009686.1\|WP_016099313.1\|5123652_5125464_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP009686.1\|WP_046393106.1\|5135923_5136931_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.43227e-31
NZ_CP009686.1\|WP_002005985.1\|5139598_5140309_-\|YwmB-family-TATA-box-binding-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	5.16446e-34
NZ_CP009686.1\|WP_000457978.1\|5131105_5132107_-\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0
NZ_CP009686.1\|WP_000467956.1\|5129220_5129898_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.20652e-81
NZ_CP009686.1\|WP_000411274.1\|5138254_5139559_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0

>NZ_CP009686.1|WP_000008901.1|5132848_5132983_-|hypothetical-protein
MSFLFVLSTAIILLFVLFTLYYYIAGKKEVPHHQLLEEEFEREE
>NZ_CP009686.1|WP_000544012.1|5132267_5132540_-|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPELANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP009686.1|WP_000457978.1|5131105_5132107_-|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNSGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
>NZ_CP009686.1|WP_000931959.1|5130243_5130678_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP009686.1|WP_000467956.1|5129220_5129898_-|CpsD/CapB-family-tyrosine-protein-kinase
MFGRKKRKPLRQLITHKEPKSRITEQYRNIRTNIEFTSVDNHVRSIIVTSADPGDGKTTTISNLAVVFGQQGKKVLLIGADLRKPTIQNLFAIHSSNGLTNLLSGQAKLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRAMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKASGKLLGVVLNDKREEKEQYGYY
>NZ_CP009686.1|WP_000393152.1|5128215_5128962_-|capsular-polysaccharide-biosynthesis-protein
MEETISLKELFHILKKRLAMILVIAFGAAIVSAIISFFFMTPIYQSSTQILVNQKKQEGAVIQYNEVQTNIQLTNTYKVIIKSPVILEQVKEKLGLNIPVQELNKRIEVTNEKDSQVVTVTAQDNDPKVARDIANTIAEIFKSEVAKIMSVDNVTVLSKAEIMENQSPIKPVPMLNIAIAFIVGLMAAFGLVFLLEFLDNTVKKEEDVENLLGLPVLGVVARMDEETQINRSVHTSSSRKVRGQTIGS
>NZ_CP009686.1|WP_016099316.1|5127524_5128226_-|CpsD/CapB-family-tyrosine-protein-kinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAIDTNLHSLMVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQVDNIFGLTNVLTHSERLEKCVQTTLVDNLHFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDMPPILAVTDAQIMANVCDASILVVRSESTEKETAVKAKGLLESAKGKLLGVVLNDREREQGLYYYYGAN
>NZ_CP009686.1|WP_046393104.1|5126652_5127420_-|tyrosine-protein-phosphatase
MIDLHCHILHGIDDGAQTVTDSLAMAQQAVSEGIHTIVATPHHQNGKYVNERTSIIHHVKQLNDELQQHNIPLTILPGQEVRLYGDLLEDYEAGKIVTLNETNKYIFIEFPSNHVPRYTEQLLYELRVKGMIPIIVHPERNAELIERPDKLYNLVNKGALTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMVASDAHNTTSRGFHLAESYELIEKEFGMNVMSDLKENPYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP009686.1|WP_016099314.1|5125524_5126406_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIVVTGKGKRAIEDHFDHSFELEQSLLEKGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPENETHRYGIIDPIEQNDRSYQVRQFVEKPAQGTAPSNLAIMGRYVLTPEIFMFLENQQTGAGGEIQLTDAIQRLNEIQRVFAYDFEGTRYDVGEKFGFIKTTIEMALQHEELKEELMKYMNELVQKEKVQA
>NZ_CP009686.1|WP_016099313.1|5123652_5125464_-|polysaccharide-biosynthesis-protein
MSYRKRLSLLILLDSFIVLTAVYLSYWFIHPNVLSKIPTTVVISSITLLCSHHIFAAIYKLYNKAWEYASIGELKQIFKAITLSILVTAIVQQIINHDIYVRILAIAWMLHLLLIGGSRFVWRMFRDTYITKATDKKRTLIIGAGSAGTMVVRQLQHNKEADLYPIAFVDDDRNKQKLEIYNVPVVGTTNHIQEIVEDNDIEHIIIAIPSLNRGQINEIFEKCRKTKAKTQIVPMLEDLLDGKLSVNEFRDVQVEDLLGREPIKLDDAGIGEKIKGKTILVTGAGGSIGSEICRQVMKYKPAKIVLLGHGENSIYNIEMEMRVTYKDTVEITTEIADVQDRHKIFEIMKKHQPYIVYHAAAHKHVPLMERNPEEAVKNNIFGTKNVAEAADTFKVNTFVMVSTDKAVNPTNVMGATKRFAEMIVQHMASVSNSTRFVAVRFGNVLGSRGSVIPLFKKQIQKGGPVTVTHPDMIRYFMTIPEASRLVIQAGTLARGGELFVLDMGDPVKILDLAKNLITLSGYSIEEIGIEFTGLRPGEKMYEELLNEGEIHPEQIFPKIHIGKAVLIDQDILMKFMNDFEGMNKGEIRERLLDIANNKNQMPI
>NZ_CP009686.1|WP_006926555.1|5134192_5134900_-|ABC-transporter-permease
MTFSMKRFSAIVRKEISDAGKNSQVILMALLPILLAVFYSNMDSIKEFFAGFIIVMTITMVGSYVQAIIIAEEKEKHTLRVLMLSPASPIEVILGKSVLTVFFVLASSFISLVILDTFKGNISMLVIIILIGTLLCVVLGTIVGLLSQNIAQTSILGLPIFIIFIMGPMLQEMVKNEFIIKVVKLLPTNHVMEALQKVIKGEGFIAIQEHILNNTIWTICLIILCIIVYKKKQLD
>NZ_CP009686.1|WP_046393105.1|5134899_5135742_-|ABC-transporter-ATP-binding-protein
MTLAIEMKDVMKSFDGKTALGNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSIYDNLLLFCDLYDCKKERIDEVLAQVNLLDDKKTPVKKLSKGMKQRVTLARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNEEGTTIFLTTHNMDEAETLCNRIAFLCGGEIVALDTPENLRLQYAKDQIEVVLKGKRKEVVQKDELGANRISEWMKKGELLSIHSYEPTLGDIFIEVTGRGL
>NZ_CP009686.1|WP_046393106.1|5135923_5136931_-|ATP-binding-cassette-domain-containing-protein
MALLELKQLEKTNQLPEIELKVEKGQCIVLQCNNHTAKVLHRIIIGEEEASTGNVLFEGEAIGKKNYSCIGFCFLKDEAYDRLKVKEYFKFLIGLYESKISIEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRMMIHNPDLVILEEPEQNVDIESTIIIRKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEVEEVGEEKVIQMIPQMKLERIPAKVNDKIILLDPMEIHFIETQNGVTHIHVREGDFVCALTLSELEARLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP009686.1|WP_000672663.1|5137028_5138048_-|stage-II-sporulation-protein-D
MKFSKPLFITVALLIALVIIVPAALVIPFAKAKVGEETASKTPPAIESIPAPGKVDTAVQVAVYREKQKKVETLPVEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLSGGKKNNADVTDTVKDQVYKSKDELKKQWGNNYENNLKKIEEAVSKTAGQVLTYDGKPISASFFSTSNGRTENAADYWGNDYPYLKSVDSPWDQASPKFTSEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKEVREKLDLRSSDFTWKQQGDKIIVTTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVEIKTMNDYEGKLMVKK
>NZ_CP009686.1|WP_000411274.1|5138254_5139559_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDSSKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVAATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVNFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP009686.1|WP_002005985.1|5139598_5140309_-|YwmB-family-TATA-box-binding-protein
MKLKLKAILIVALSVVLFLVGYREMKPISDEQKMESMIKALEKNDAKVEKWSWLARETKTISNIHTFQKLLNDVKEKANIQKWEVEQSPDGYKATSYKKLSSYEERVVVTWSKENTKENTFIIFEVSGAKWDPKYVQNMNKIFSEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTDNKDTIVVGTPIITSEY
>NZ_CP009686.1|WP_000057889.1|5140354_5140591_-|DUF1146-domain-containing-protein
MAQLLGQQALIAIVSHLLFITITWWALQGIHIERLMKSGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP009686.1|WP_000367481.1|5140793_5142314_-|NADH-quinone-oxidoreductase-subunit-NuoN
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKSRASNEAAMKYVISGGIGTAIALFGMSYLYGITGSTNIIDMQKVLTGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGAATPVTAFLGTISKIAGFLLIIRLFLMIFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNIKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQNNEENITIFTGLYKRSPFTAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP009686.1|WP_046393107.1|5142315_5143818_-|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKELRTVRALGLFGTALPFGIAAVLACTYASGKNLSLFDEKMKWIKFGDFTAVDKRWFSIYYELGIDGLSLVMMVLTALLATLAAIAAFSIKRNLKAFYMLLLMLEIGMLGVFAAQNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIVFSILFAKTGTTNIVELKEILRSVNAEGALVIPSSLQLSVFIAIMIAFAIKLPVFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGIIRFGKGLFPEYFHDVATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLAALNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSDITALGGLAKSVPVLSGFFLAGGMASLGLPGMSGFVSEFLAFLGLFQGEPVIAAVGVIGIILTAVYVLRATLQVTFGKKEWEAKSDIHGWEYVPVLLLIFCIIAIGVMPEILGDPLQNTLKTLGVK
>NZ_CP009686.1|WP_046393108.1|5143814_5145677_-|NADH-quinone-oxidoreductase-subunit-L
MIDYAWLIPLFPLVSFLLLIIFGKKIREGSSVLSIFFVFLSFILAVLVLIERFSEASVKHKWVWLRAGDVDISFGFEVTALGALMLFIVTLVSLLVHVYSKGYMKGDERLPTFYAYLGLFTFAMLGLVISTNLLQLYIFWELVGLGSFLLIGFYFFKEEAKAAAKKAFIMTRIGDVGLFIGMILIFWYAGSFEYDAIFRAIYTGDLPPYMITITAILIFIGAMGKSGQFPLHTWLPDAMEGPTPVSALIHAATMVAAGVYLVATMFPLFSASTVAMQTVAIIGAFTAIFAASIGLVQTDIKRVLAYSTVSQLGYMMLALGSAGYVAGIFHLTTHAFFKALLFLAAGSVIHAVHTQNINKMGGLQKKMKVTGTLFLIGTLAISGVPLLSGFFSKDEILVATWMNGNYVLFTLAVIAAFLTAFYMFRLYFLVFTGETKTKEEVHESPRDMTYPMIVLGVLAVVAGYINTPWFGTFLGDWLTKDVGFKVEEAHGPVWIMIVATLVSFAGIALAYFIYGKKSISRDWAGGTETSLYNLLKEKYYVDELYNMTVIPITKGIAHVLRLFEVYVVEGIAVLIASVVKGTSNLGSKLQNGNVQVYGTVTAVSLAVLVIILLYTGGDLR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP009686_1	1.1\|5133194\|31\|NZ_CP009686\|CRISPRCasFinder	5133194-5133224	31	JX238501	Bacillus phage phiAGATE, complete genome	124559-124589	8	0.742
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	22854-22887	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	22191-22224	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	22191-22224	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	22191-22224	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	22191-22224	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	21831-21864	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	22983-23016	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	21454-21487	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	22007-22040	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	22308-22341	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	21930-21963	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	22137-22170	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	22057-22090	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	21673-21706	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	21655-21688	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	22983-23016	9	0.735
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47181-47214	11	0.676
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47565-47598	11	0.676
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	47949-47982	11	0.676
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48333-48366	11	0.676
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	48717-48750	11	0.676
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49101-49134	11	0.676
NZ_CP009686_1	1.2\|5133248\|34\|NZ_CP009686\|CRISPRCasFinder	5133248-5133281	34	NZ_HG813246	Staphylococcus epidermidis PM221 plasmid 1, complete sequence	49485-49518	11	0.676

1. spacer 1.1|5133194|31|NZ_CP009686|CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 8, identity: 0.742

ttcttcttttttgtcactagttgaaccgctt	CRISPR spacer
ctaaccttttttgccactagttaaaccgccc	Protospacer
.*  .********.********.******..

2. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

3. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

4. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

5. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

6. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

7. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

8. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

9. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

10. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

11. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

12. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

13. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

14. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

15. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

16. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

17. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 9, identity: 0.735

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.* ***********.********* **   *.

18. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

19. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

20. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

21. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

22. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

23. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

24. spacer 1.2|5133248|34|NZ_CP009686|CRISPRCasFinder matches to NZ_HG813246 (Staphylococcus epidermidis PM221 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

cttgtcttctgttttactttctggtttcgtgctc	CRISPR spacer
tatgtcttctgtttttgtttctggttccccagct	Protospacer
. *************  *********.* .. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

258311 : 266259

uncultured_virus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000917311.1\|258311_258596_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.2e-20	54.8
WP_044307015.1\|258634_260269_+	chaperonin GroEL	A0A219YK78	uncultured_virus	2.6e-157	58.0
WP_000743909.1\|260675_262214_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	8.8e-22	31.7
WP_000833082.1\|262598_263924_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	6.4e-45	30.1
WP_000929885.1\|264068_264770_+	response regulator transcription factor	W8CYM9	Bacillus_phage	7.3e-40	36.9
WP_000719205.1\|264753_266259_+	aminopeptidase AmpS	W8CYF6	Bacillus_phage	5.4e-32	30.3

DBSCAN-SWA_2

311832 : 320208

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000625682.1\|311832_313140_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.3
WP_001170544.1\|313228_313948_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-49	44.3
WP_000278823.1\|313940_314195_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666786.1\|314191_314875_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000055562.1\|314858_317078_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	2.6e-163	41.2
WP_000879025.1\|317062_318478_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.3e-55	35.4
WP_001262439.1\|318583_319624_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.2e-67	45.9
WP_000088594.1\|319620_320208_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.1e-28	37.4

DBSCAN-SWA_3

651025 : 659177

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_116269190.1\|651025_651994_-	YafY family transcriptional regulator	A0A1B0RXM1	Streptococcus_phage	1.4e-17	29.9
WP_000085783.1\|652073_652595_+	dihydrofolate reductase	NA	NA	NA	NA
WP_046392352.1\|652760_654152_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.1e-31	29.2
WP_006918011.1\|654163_654841_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-32	35.6
WP_000738879.1\|655016_656264_+	hypothetical protein	NA	NA	NA	NA
WP_000277056.1\|656397_656928_+	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	2.5e-16	34.3
WP_025710086.1\|656940_657285_+	DUF4064 domain-containing protein	A0A0S2MVJ2	Bacillus_phage	4.2e-41	77.2
WP_025710085.1\|657725_659177_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	9.8e-140	54.0

DBSCAN-SWA_4

1689783 : 1706577

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046392570.1\|1689783_1690236_+	hypothetical protein	A0A0K2CP30	Brevibacillus_phage	8.6e-26	45.8
WP_000077128.1\|1690235_1691324_+	hypothetical protein	A0A0K2CNX7	Brevibacillus_phage	1.2e-94	55.8
WP_046392571.1\|1691557_1692028_+	hypothetical protein	A0A0K2CPC8	Brevibacillus_phage	7.1e-31	69.4
WP_000743719.1\|1692114_1692357_+	hypothetical protein	A0A0K2CP74	Brevibacillus_phage	2.1e-18	55.0
WP_046392572.1\|1692429_1697769_+	hypothetical protein	A0A0K2CPN3	Brevibacillus_phage	5.4e-143	26.8
WP_000068593.1\|1697827_1698445_+	S-layer homology domain-containing protein	A0A0K2CPJ2	Brevibacillus_phage	1.4e-71	60.7
WP_046392573.1\|1698447_1699521_+	hypothetical protein	A0A0K2CP35	Brevibacillus_phage	4.1e-74	40.3
WP_046392574.1\|1699534_1702726_+	M23 family metallopeptidase	A0A0K2CNY2	Brevibacillus_phage	3.7e-06	50.0
WP_046392575.1\|1702804_1703521_+	hypothetical protein	NA	NA	NA	NA
WP_046392576.1\|1703535_1703976_+	hypothetical protein	NA	NA	NA	NA
WP_046392577.1\|1703991_1706577_+	hypothetical protein	A0A0K2CPJ7	Brevibacillus_phage	1.6e-31	44.2

DBSCAN-SWA_5

1719505 : 1734070

Brevibacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000022193.1\|1719505_1720627_+	hypothetical protein	A0A0K2CPP1	Brevibacillus_phage	7.3e-66	37.0
WP_000537240.1\|1720638_1721370_+	hypothetical protein	NA	NA	NA	NA
WP_000345536.1\|1721448_1721892_+	hypothetical protein	A0A0K2CPK2	Brevibacillus_phage	3.0e-23	40.6
WP_001111326.1\|1721967_1722459_+	hypothetical protein	A0A0K2CNZ3	Brevibacillus_phage	2.4e-37	55.2
WP_046392583.1\|1722499_1723111_+	hypothetical protein	A0A127AW14	Bacillus_phage	6.3e-48	51.6
WP_046392584.1\|1723095_1725990_+	hypothetical protein	A0A0K2CPP4	Brevibacillus_phage	2.2e-13	30.4
WP_046392585.1\|1726032_1730388_+	DNRLRE domain-containing protein	A0A0K2CP88	Brevibacillus_phage	1.7e-33	24.3
WP_046392586.1\|1730957_1731326_+	hypothetical protein	NA	NA	NA	NA
WP_000655295.1\|1731325_1731703_+	hypothetical protein	NA	NA	NA	NA
WP_046392587.1\|1731902_1732910_+	LysM peptidoglycan-binding domain-containing protein	D6QWN1	uncultured_phage	4.1e-28	36.1
WP_046392588.1\|1732926_1733226_+	hypothetical protein	A0A0K2CPL0	Brevibacillus_phage	1.1e-21	58.2
WP_000540599.1\|1733245_1734070_+	hypothetical protein	A7KV11	Bacillus_phage	1.4e-79	69.4

DBSCAN-SWA_6

1742193 : 1751581

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000177372.1\|1742193_1742901_-	DNA polymerase I	A0A0K2CNW2	Brevibacillus_phage	7.3e-64	53.5
WP_000781409.1\|1743069_1743474_-	hypothetical protein	NA	NA	NA	NA
WP_002164576.1\|1744097_1745492_-	DNA polymerase I	A0A0K2CP19	Brevibacillus_phage	1.9e-103	45.6
WP_000207534.1\|1745578_1746238_-	hypothetical protein	A0A0K2CPH8	Brevibacillus_phage	4.7e-57	56.9
WP_001090550.1\|1746703_1747261_-	sigma-70 family RNA polymerase sigma factor	A0A0K2CPD2	Brevibacillus_phage	2.4e-25	41.1
WP_046392596.1\|1747288_1748365_-	toprim domain-containing protein	A0A0K2CNW6	Brevibacillus_phage	4.9e-104	54.0
WP_046392597.1\|1748389_1749682_-	DNA helicase	A0A0K2CP24	Brevibacillus_phage	2.5e-139	57.9
WP_046392598.1\|1750161_1750932_-	ATP-binding protein	A0A0K2CNX1	Brevibacillus_phage	2.0e-62	48.8
WP_000277551.1\|1750990_1751581_-	helix-turn-helix domain-containing protein	A0A0K2CNS5	Brevibacillus_phage	2.3e-26	43.4

DBSCAN-SWA_7

1926050 : 1934153

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044307235.1\|1926050_1927346_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.3e-13	32.3
WP_001194314.1\|1927445_1928210_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_016122339.1\|1928450_1930211_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	9.1e-273	98.0
WP_000612413.1\|1930296_1930974_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.5e-122	98.7
WP_001231629.1\|1930970_1932044_+	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	1.4e-186	97.8
WP_000818985.1\|1932271_1932991_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_001258539.1\|1933280_1934153_+	aminoglycoside 6-adenylyltransferase	E4ZFP8	Streptococcus_phage	2.8e-65	44.4

DBSCAN-SWA_8

2545950 : 2618427

Bacillus_phage(63.41%)

holin,capsid,terminase,tail,head,bacteriocin,portal,protease,integrase

attL 2563132:2563161|attR 2625009:2625038

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001071364.1\|2545950_2546271_+\|bacteriocin	heterocycloanthracin/sonorensin family bacteriocin	NA	NA	NA	NA
WP_002024190.1\|2546760_2547246_+	hypothetical protein	NA	NA	NA	NA
WP_046392719.1\|2547557_2548229_+	DUF3962 domain-containing protein	NA	NA	NA	NA
WP_046392720.1\|2548297_2549407_-\|integrase	site-specific integrase	A0A0U3U8Y8	Bacillus_phage	4.1e-146	78.4
WP_046392721.1\|2549710_2550949_+	collagen-like protein	NA	NA	NA	NA
WP_046392722.1\|2551590_2552742_+	hypothetical protein	NA	NA	NA	NA
WP_046392723.1\|2552779_2552926_+	hypothetical protein	NA	NA	NA	NA
WP_016095531.1\|2553245_2553599_-	helix-turn-helix transcriptional regulator	A0A0U3SD25	Bacillus_phage	9.6e-49	87.1
WP_046392724.1\|2553799_2553991_+	helix-turn-helix transcriptional regulator	A0A0U3SLC2	Bacillus_phage	8.3e-23	86.9
WP_000522030.1\|2554047_2554314_+	helix-turn-helix domain-containing protein	A0A0U3ULL9	Bacillus_phage	2.9e-37	94.1
WP_046392726.1\|2554535_2555591_+	DnaD domain protein	W8CYG5	Bacillus_phage	1.1e-58	41.7
WP_046392727.1\|2555594_2555873_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	2.3e-13	60.3
WP_016512772.1\|2555865_2556225_+	hypothetical protein	A0A1B1P7A1	Bacillus_phage	3.5e-30	51.7
WP_000717826.1\|2556243_2556411_+	DUF3954 domain-containing protein	A0A1B0T6B8	Bacillus_phage	1.4e-13	62.3
WP_000109500.1\|2556436_2556688_+	hypothetical protein	A0A0K2CNP4	Brevibacillus_phage	2.2e-07	37.3
WP_046392728.1\|2556707_2557190_+	nucleoside triphosphate pyrophosphohydrolase family protein	A0A0U4IBD0	Bacillus_phage	4.4e-20	47.4
WP_046392729.1\|2557334_2558123_-	sulfotransferase family 2 domain-containing protein	A0A288WG17	Bacillus_phage	5.0e-106	72.7
WP_046392730.1\|2558451_2558916_-	hypothetical protein	NA	NA	NA	NA
WP_046392731.1\|2559739_2560309_-	cupin domain-containing protein	Q2I8C5	Bacillus_phage	1.5e-88	94.3
WP_046392732.1\|2560505_2560973_-	hypothetical protein	NA	NA	NA	NA
WP_001123250.1\|2562429_2562714_-	DUF4183 domain-containing protein	NA	NA	NA	NA
WP_116344833.1\|2563000_2563132_+	DUF3983 domain-containing protein	A0A1B1P7V8	Bacillus_phage	1.3e-11	81.4
2563132:2563161	attL	NA	NA	NA	NA
WP_046392734.1\|2563434_2563917_+	ArpU family transcriptional regulator	H0USV3	Bacillus_phage	1.1e-68	80.0
WP_046392735.1\|2563916_2564459_+\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	4.3e-88	90.6
WP_001170296.1\|2564673_2565624_+	nucleoside hydrolase	NA	NA	NA	NA
WP_046392736.1\|2566018_2566720_+	hypothetical protein	NA	NA	NA	NA
WP_046392737.1\|2567263_2568016_+	hypothetical protein	NA	NA	NA	NA
WP_046392738.1\|2568059_2568239_+	hypothetical protein	NA	NA	NA	NA
WP_046392739.1\|2568252_2568504_+	hypothetical protein	A0A288WFY9	Bacillus_phage	6.0e-05	41.9
WP_046392740.1\|2568500_2568815_+	hypothetical protein	Q2I8B8	Bacillus_phage	1.7e-09	53.1
WP_046392741.1\|2568819_2569050_+	hypothetical protein	NA	NA	NA	NA
WP_046392742.1\|2569042_2569378_+	HNH endonuclease	D2XR61	Bacillus_phage	1.0e-52	91.9
WP_016125621.1\|2569501_2569813_+	hypothetical protein	D2XR14	Bacillus_phage	1.6e-39	87.3
WP_016125622.1\|2569809_2571495_+\|terminase	terminase large subunit	D2XR15	Bacillus_phage	2.9e-276	85.9
WP_046392743.1\|2571515_2572667_+\|portal	phage portal protein	A8AT96	Listeria_phage	1.8e-104	51.1
WP_000791073.1\|2572656_2573382_+\|protease	Clp protease ClpP	A0A2H4J8Y7	uncultured_Caudovirales_phage	1.7e-44	53.2
WP_000245092.1\|2573408_2574575_+\|capsid	phage major capsid protein	A0A2H4JH29	uncultured_Caudovirales_phage	9.6e-162	77.7
WP_016125626.1\|2574587_2574881_+	hypothetical protein	A0A2H4JG04	uncultured_Caudovirales_phage	2.4e-37	78.4
WP_023522880.1\|2574882_2575233_+\|head	phage head closure protein	D2XR20	Bacillus_phage	1.9e-52	87.8
WP_025710295.1\|2575234_2575579_+	hypothetical protein	D2XR21	Bacillus_phage	2.5e-49	86.6
WP_046392744.1\|2575575_2575905_+	hypothetical protein	A0A2H4JAG4	uncultured_Caudovirales_phage	7.1e-54	93.6
WP_046392745.1\|2575905_2576493_+\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	8.7e-87	81.5
WP_046392746.1\|2576497_2576860_+	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	2.2e-56	89.2
WP_046392747.1\|2577090_2578554_+	hypothetical protein	A0A2H4JAI2	uncultured_Caudovirales_phage	4.1e-186	85.1
WP_046392748.1\|2578771_2580937_+\|tail	phage tail tape measure protein, TP901 family, core region	A0A2H4JC82	uncultured_Caudovirales_phage	9.0e-97	82.9
WP_046392749.1\|2580978_2582436_+\|tail	phage tail family protein	A0A0A7AQV1	Bacillus_phage	9.8e-172	59.5
WP_046392750.1\|2582432_2587532_+	phage minor structural protein	A0A0S2MVB4	Bacillus_phage	0.0e+00	58.4
WP_046392751.1\|2587543_2587924_+	hypothetical protein	A0A0S2MVE0	Bacillus_phage	2.9e-43	71.7
WP_046392752.1\|2587958_2588384_+\|holin	phage holin family protein	A0A0S2MVC4	Bacillus_phage	6.3e-71	97.2
WP_046392753.1\|2588383_2589100_+	N-acetylmuramoyl-L-alanine amidase	A0A0S2MVR5	Bacillus_phage	8.1e-87	94.5
WP_046392754.1\|2589294_2590767_-	hypothetical protein	NA	NA	NA	NA
WP_046392755.1\|2590901_2591486_+	restriction endonuclease	NA	NA	NA	NA
WP_046392756.1\|2591637_2591916_+	hypothetical protein	NA	NA	NA	NA
WP_116344820.1\|2592305_2593988_+	RNAseH domain-containing protein	NA	NA	NA	NA
WP_044307542.1\|2594194_2594962_+	DUF3959 family protein	NA	NA	NA	NA
WP_000905571.1\|2595106_2595523_+	DUF3995 domain-containing protein	NA	NA	NA	NA
WP_000878369.1\|2595643_2595847_+	hypothetical protein	NA	NA	NA	NA
WP_000362067.1\|2596176_2596389_-	hypothetical protein	NA	NA	NA	NA
WP_025710280.1\|2596598_2597603_+	DUF1835 domain-containing protein	NA	NA	NA	NA
WP_000282680.1\|2597748_2598153_+	hypothetical protein	NA	NA	NA	NA
WP_046392757.1\|2598312_2599548_+	cytochrome P450	NA	NA	NA	NA
WP_000106383.1\|2599815_2601099_+	MFS transporter	NA	NA	NA	NA
WP_046392758.1\|2601088_2601721_+	Vat family streptogramin A O-acetyltransferase	A0A2R8FE91	Brazilian_cedratvirus	2.7e-25	42.4
WP_000046095.1\|2601791_2601947_+	DUF1540 domain-containing protein	NA	NA	NA	NA
WP_044307539.1\|2602048_2602546_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_016122580.1\|2602686_2603901_+	cytochrome P450	NA	NA	NA	NA
WP_000954432.1\|2604009_2604588_+	cysteine dioxygenase	NA	NA	NA	NA
WP_000766385.1\|2604763_2605615_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_046392759.1\|2606065_2607853_+	PAS domain-containing protein	NA	NA	NA	NA
WP_044307537.1\|2608087_2610214_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_046392760.1\|2610310_2610820_+	signal peptidase I	NA	NA	NA	NA
WP_000932145.1\|2611079_2612267_+	UDP-glucosyltransferase	A0A2H4ZK81	Cryptophlebia_leucotreta_granulosis_virus	8.9e-06	24.1
WP_044307535.1\|2612357_2613038_-	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_001038210.1\|2613447_2613996_+	ECF-type riboflavin transporter substrate-binding protein	NA	NA	NA	NA
WP_044307534.1\|2614006_2615707_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	4.0e-15	31.4
WP_000556373.1\|2615699_2616500_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000120182.1\|2616636_2616744_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_046392761.1\|2616836_2618105_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	2.0e-24	29.1
WP_080342248.1\|2618241_2618427_-\|integrase	tyrosine-type recombinase/integrase	A0A090EUH1	Clostridium_phage	1.2e-10	53.3
2625009:2625038	attR	NA	NA	NA	NA

DBSCAN-SWA_9

3641246 : 3651404

Bacillus_phage(54.55%)

bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000413738.1\|3641246_3641867_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	8.2e-19	62.2
WP_006920048.1\|3641957_3642761_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_000031384.1\|3642761_3643304_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_001102628.1\|3643296_3643620_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_000392444.1\|3643991_3644222_-\|bacteriocin	bacteriocin biosynthesis protein	A0A1B1P7Q9	Bacillus_phage	1.5e-23	73.7
WP_016123244.1\|3644283_3645180_-	hypothetical protein	A0A0S2MVR5	Bacillus_phage	4.6e-79	52.1
WP_006920050.1\|3645452_3646295_-	M23 family metallopeptidase	A0A218KCJ1	Bacillus_phage	6.1e-33	47.7
WP_033692154.1\|3646413_3647400_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.7e-34	43.9
WP_000464425.1\|3647638_3648025_-	DUF1492 domain-containing protein	A0A288WG73	Bacillus_phage	2.6e-47	71.4
WP_033696536.1\|3648143_3649010_-	DnaD domain protein	A0A2H4J394	uncultured_Caudovirales_phage	1.2e-95	63.0
WP_001189065.1\|3649162_3649357_-	hypothetical protein	A0A1C8E9A1	Bacillus_phage	1.7e-15	71.0
WP_046392955.1\|3649368_3650127_-	antirepressor	A0A2H4JBC7	uncultured_Caudovirales_phage	1.2e-96	69.0
WP_000283431.1\|3650329_3650542_-	hypothetical protein	A6M975	Geobacillus_virus	1.6e-11	63.0
WP_006920059.1\|3650732_3651404_+	helix-turn-helix domain-containing protein	A0A2H4J441	uncultured_Caudovirales_phage	6.8e-35	41.0

DBSCAN-SWA_10

4439080 : 4446766

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000221064.1\|4439080_4440004_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.0e-46	44.0
WP_000247679.1\|4440129_4441065_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.1e-22	25.3
WP_000018029.1\|4441066_4441759_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.4e-06	28.8
WP_001014310.1\|4442101_4442296_+	YwbE family protein	NA	NA	NA	NA
WP_001255971.1\|4442334_4443534_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.6e-71	41.2
WP_000587820.1\|4443829_4444153_+	heme oxygenase	NA	NA	NA	NA
WP_001086122.1\|4444225_4444990_-	class B sortase	NA	NA	NA	NA
WP_044306745.1\|4445022_4445793_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	7.6e-14	27.9
WP_001036848.1\|4445782_4446766_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	27.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage