CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LN774770	Lactococcus piscium MKFS47 plasmid II, complete sequence	0 crisprs	NA	0	1	0
NZ_LN774771	Lactococcus piscium MKFS47 plasmid III, complete sequence	1 crisprs	csa3	1	0	0
NZ_LN774769	Lactococcus piscium MKFS47 chromosome I	1 crisprs	DEDDh,cas3,WYL,DinG,csa3	0	11	2

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2933 : 50186

Streptococcus_phage(46.15%)

holin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047916692.1\|2933_3614_+\|transposase	IS6-like element ISS1N family transposase	A0A1X9I6C6	Streptococcus_phage	5.0e-110	84.1
WP_082095486.1\|3849_6516_-	cation-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	2.6e-93	32.0
WP_047916693.1\|7292_7541_-\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	6.0e-13	48.8
WP_047916695.1\|8654_8930_-\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	8.9e-10	43.5
WP_047916697.1\|9687_10017_+	hypothetical protein	NA	NA	NA	NA
WP_047916698.1\|10013_14666_+	DEAD/DEAH box helicase	A0A2H4UTW8	Bodo_saltans_virus	5.9e-53	28.7
WP_068876876.1\|15197_15302_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_047916699.1\|15464_15902_-	hypothetical protein	NA	NA	NA	NA
WP_047916700.1\|16115_17606_-	replication protein RepR	NA	NA	NA	NA
WP_047916701.1\|17971_18223_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047916702.1\|18506_19283_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_047916703.1\|19344_19716_-	hypothetical protein	NA	NA	NA	NA
WP_047916704.1\|19742_20663_-	hypothetical protein	NA	NA	NA	NA
WP_047916705.1\|20677_21610_-	hypothetical protein	NA	NA	NA	NA
WP_047916706.1\|21609_22530_-	hypothetical protein	NA	NA	NA	NA
WP_047916707.1\|22549_24208_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_047916708.1\|24200_24632_-	hypothetical protein	NA	NA	NA	NA
WP_047916709.1\|24636_25188_-	hypothetical protein	NA	NA	NA	NA
WP_052727809.1\|25199_26309_-	CHAP domain-containing protein	A0A1S5SEZ8	Streptococcus_phage	1.7e-38	47.6
WP_047916710.1\|26321_27674_-	conjugal transfer protein TraF	NA	NA	NA	NA
WP_047916711.1\|27687_29649_-	TrsE protein	NA	NA	NA	NA
WP_047916712.1\|29659_30289_-	hypothetical protein	NA	NA	NA	NA
WP_047916713.1\|30304_30688_-	hypothetical protein	NA	NA	NA	NA
WP_047916714.1\|30707_31037_-	hypothetical protein	NA	NA	NA	NA
WP_047916715.1\|31053_33024_-	MobA/MobL family protein	NA	NA	NA	NA
WP_047916716.1\|33308_33608_+	hypothetical protein	NA	NA	NA	NA
WP_047916717.1\|33610_33910_+	hypothetical protein	NA	NA	NA	NA
WP_047916718.1\|33886_34180_-	hypothetical protein	NA	NA	NA	NA
WP_047916719.1\|34195_34708_-	molecular chaperone DnaJ	NA	NA	NA	NA
WP_157761154.1\|34973_35132_+	hypothetical protein	NA	NA	NA	NA
WP_082095487.1\|35148_36009_-	toxin zeta	NA	NA	NA	NA
WP_047916720.1\|36010_36283_-	antitoxin	NA	NA	NA	NA
WP_157761155.1\|36303_36561_-	hypothetical protein	NA	NA	NA	NA
WP_047916722.1\|36596_36806_-	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	6.7e-26	84.1
WP_047916723.1\|36910_37768_-	ParA family protein	A0A1X9I765	Streptococcus_phage	4.0e-125	80.9
WP_047916724.1\|37903_40048_-	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	4.7e-223	79.6
WP_052727810.1\|40139_41423_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_047916725.1\|41828_42350_-	hypothetical protein	NA	NA	NA	NA
WP_047916726.1\|42360_42954_-	recombinase family protein	A0A1V0E035	Clostridioides_phage	2.7e-19	35.1
WP_047916727.1\|42963_43170_-	hypothetical protein	NA	NA	NA	NA
WP_047916728.1\|43327_43672_-	hypothetical protein	NA	NA	NA	NA
WP_047916692.1\|43907_44588_+\|transposase	IS6-like element ISS1N family transposase	A0A1X9I6C6	Streptococcus_phage	5.0e-110	84.1
WP_082095488.1\|44813_46175_+	AAA family ATPase	NA	NA	NA	NA
WP_047916730.1\|46182_47025_+	DUF4435 domain-containing protein	NA	NA	NA	NA
WP_047916731.1\|47159_47708_+	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	1.0e-33	44.0
WP_047916732.1\|47813_48083_-	N-acetyltransferase	NA	NA	NA	NA
WP_082095489.1\|48101_48275_-	N-acetyltransferase	NA	NA	NA	NA
WP_147806244.1\|48445_48895_-	hypothetical protein	NA	NA	NA	NA
WP_047916734.1\|48896_49145_-	hypothetical protein	NA	NA	NA	NA
WP_047914927.1\|49250_50186_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	8.3e-31	33.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_LN774771

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LN774771_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN774771_1

37714-37795

Orphan

Consensus_repeat	Method
AATAACATTCAAGTGTTTGTTTGAATA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_LN774771_1

>merge|NZ_LN774771|1|37714-37795|CRISPRCasFinder
AATAACATTCAAGTGTTTGTTTGAATATTTACAAATATATAATAACAGATTAAAGAATAACATTCAAGTGTTTGTTTGAATA

>NZ_LN774771|1|1|37714-37795|CRISPRCasFinder
AATAACATTCAAGTGTTTGTTTGAATA	TTTACAAATATATAATAACAGATTAAAG
AATAACATTCAAGTGTTTGTTTGAATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN774771.1\|WP_003134160.1\|43242_45147_+\|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319849
NZ_LN774771.1\|WP_082095493.1\|40385_40619_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380161
NZ_LN774771.1\|WP_047916777.1\|34229_34910_-\|IS6-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_LN774771.1\|WP_047916771.1\|23592_26670_+\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NZ_LN774771.1\|WP_047916770.1\|22250_23141_-\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NZ_LN774771.1\|WP_047916780.1\|40744_40981_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN774771.1\|WP_047916774.1\|29753_31517_+\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
NZ_LN774771.1\|WP_047916778.1\|35572_37696_-\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319845
NZ_LN774771.1\|WP_014727478.1\|32358_33039_+\|IS6-like-element-ISS1N-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_LN774771.1\|WP_047916781.1\|45704_45905_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN774771.1\|WP_099046847.1\|37922_38426_+\|signal-peptidase-II	unknown	unknown	gnl\|CDD\|376504
NZ_LN774771.1\|WP_047916776.1\|33147_33912_-\|(S)-acetoin-forming-diacetyl-reductase	unknown	unknown	gnl\|CDD\|181518
NZ_LN774771.1\|WP_047916782.1\|45912_46287_-\|Hg(II)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|131106
NZ_LN774771.1\|WP_039670419.1\|45147_45495_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173534
NZ_LN774771.1\|WP_047916772.1\|26669_28265_+\|type-I-restriction-modification-system-subunit-M	unknown	unknown	gnl\|CDD\|211578
NZ_LN774771.1\|WP_047916773.1\|28257_29418_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341198
NZ_LN774771.1\|WP_039670417.1\|41030_42320_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226400
NZ_LN774771.1\|WP_031367156.1\|23207_23576_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274787
NZ_LN774771.1\|WP_039670418.1\|42372_43152_-\|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133382
NZ_LN774771.1\|WP_047916779.1\|38597_38933_-\|Cd(II)-sensing-metalloregulatory-transcriptional-repressor-CadC	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|223713

Protein	Function_ID	Function_description	E-value
NZ_LN774771.1\|WP_003134160.1\|43242_45147_+\|heavy-metal-translocating-P-type-ATPase	gnl\|CDD\|319849	cd07551, P-type_ATPase_HM_ZosA_PfeT-like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis ZosA/PfeT which transports copper, and perhaps zinc under oxidative stress, and perhaps ferrous iron. Bacillus subtilis ZosA/PfeT (previously known as YkvW) transports copper, it may also transport zinc under oxidative stress and may also be involved in ferrous iron efflux. ZosA/PfeT is expressed under the regulation of the peroxide-sensing repressor PerR. It is involved in competence development. Disruption of the zosA/pfeT gene results in low transformability. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_LN774771.1\|WP_082095493.1\|40385_40619_+\|hypothetical-protein	gnl\|CDD\|380161	NF033092, HK_WalK, cell wall metabolism sensor histidine kinase WalK. This model describes WalK as found in Staphylococcus aureus (sp\|Q2G2U4.1\|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.	7.41168e-21
NZ_LN774771.1\|WP_047916777.1\|34229_34910_-\|IS6-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.866e-91
NZ_LN774771.1\|WP_047916771.1\|23592_26670_+\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	1.11176e-101
NZ_LN774771.1\|WP_047916770.1\|22250_23141_-\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	4.6035e-25
NZ_LN774771.1\|WP_047916774.1\|29753_31517_+\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
NZ_LN774771.1\|WP_047916778.1\|35572_37696_-\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319845	cd07545, P-type_ATPase_Cd-like, P-type heavy metal-transporting ATPase, similar to Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase. CadA from gram-positive Staphylococcus aureus plasmid pI258 is required for full Cd(2+) and Zn(2+) resistance. This subfamily also includes CadA, from the gram-negative bacilli, Stenotrophomonas maltophilia D457R, which is a cadmium efflux pump acquired as part of a cluster of antibiotic and heavy metal resistance genes from gram-positive bacteria. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_LN774771.1\|WP_014727478.1\|32358_33039_+\|IS6-like-element-ISS1N-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.0264e-91
NZ_LN774771.1\|WP_047916782.1\|45912_46287_-\|Hg(II)-responsive-transcriptional-regulator	gnl\|CDD\|131106	TIGR02051, Mercuric_resistance_operon_regulatory_protein, Hg(II)-responsive transcriptional regulator. This model represents the mercury (II) responsive transcriptional activator of the mer organomercurial resistance operon. This protein is a member of the MerR family of transcriptional activators (pfam00376) and contains a distinctive pattern of cysteine residues in its metal binding loop, Cys-X(8)-Cys-Pro, as well as a conserved and critical cysteine at the N-terminal end of the dimerization helix. [Cellular processes, Detoxification, Regulatory functions, DNA interactions].	7.12237e-54
NZ_LN774771.1\|WP_099046847.1\|37922_38426_+\|signal-peptidase-II	gnl\|CDD\|376504	pfam01252, Peptidase_A8, Signal peptidase (SPase) II.	1.16348e-38
NZ_LN774771.1\|WP_047916776.1\|33147_33912_-\|(S)-acetoin-forming-diacetyl-reductase	gnl\|CDD\|181518	PRK08643, PRK08643, (S)-acetoin forming diacetyl reductase.	7.17882e-158
NZ_LN774771.1\|WP_039670419.1\|45147_45495_+\|hypothetical-protein	gnl\|CDD\|173534	PTZ00341, PTZ00341, Ring-infected erythrocyte surface antigen; Provisional.	2.81912e-06
NZ_LN774771.1\|WP_047916772.1\|26669_28265_+\|type-I-restriction-modification-system-subunit-M	gnl\|CDD\|211578	TIGR00497, hsdM, type I restriction system adenine methylase (hsdM). Function: methylation of specific adenine residues; required for both restriction and modification activities. The ECOR124/3 I enzyme recognizes 5'GAA(N7)RTCG. for E.coli see (J. Mol. Biol. 257: 960-969 (1996)). [DNA metabolism, Restriction/modification].	4.86734e-130
NZ_LN774771.1\|WP_047916773.1\|28257_29418_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341198	cd17517, RMtype1_S_EcoKI_StySPI-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR),similar to Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) TRD2-CR2, Salmonella enterica subsp. enterica serovar Potsdam S subunit (S.StySPI) TRD2-CR2, and other TRD-CR's. Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) recognizes 5'... AACNNNNNNGTGC ... 3' and Salmonella enterica subsp. enterica serovar Potsdam S subunit (S.StySPI) recognizes 5'... AACNNNNNNGTRC ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.EcoKI-TRD1 and S.StySPI-TRD1 both recognize AAC/GTT, S.EcoKI-TRD2 recognizes GCAC/GTGC and S.StySPI-TRD2 recognizes GYAC/GTRC. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2.It also includes TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases, such as Pseudomonas putida Jo 4-731 Type IIG restriction enzyme/N6-adenine DNA methyltransferase (RM.PpiI), and type I DNA methyltransferases such as Bacillus cereus BDRD-ST24 M subunit of Type I N6-adenine DNA methyltransferase (M.Bce24ORF51270P). RM.PpiI recognizes 5' ... GAACNNNNNCTC ... 3'.	4.40734e-50
NZ_LN774771.1\|WP_039670417.1\|41030_42320_+\|CHAP-domain-containing-protein	gnl\|CDD\|226400	COG3883, COG3883, Uncharacterized protein conserved in bacteria [Function unknown].	4.76997e-43
NZ_LN774771.1\|WP_031367156.1\|23207_23576_+\|hypothetical-protein	gnl\|CDD\|274787	TIGR03794, conserved_hypothetical_protein, NHLM bacteriocin system secretion protein. Members of this protein family are homologs of the HlyD membrane fusion protein of type I secretion systems. Their occurrence in prokaryotic genomes is associated with the occurrence of a novel class of microcin (small bacteriocins) with a leader peptide region related to nitrile hydratase. We designate the class of bacteriocin as Nitrile Hydratase Leader Microcin, or NHLM. This family, therefore, is designated as NHLM bacteriocin system secretion protein. Some but not all NHLM-class putative microcins belong to the TOMM (thiazole/oxazole modified microcin) class as assessed by the presence of the scaffolding protein and/or cyclodehydratase in the same gene clusters. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products].	0.0022276
NZ_LN774771.1\|WP_039670418.1\|42372_43152_-\|MerR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|133382	cd01107, HTH_BmrR, Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BmrR and YdfL of Bacillus subtilis, and related proteins; N-terminal domain. Bmr is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. BmrR is comprised of two distinct domains that harbor a regulatory (effector-binding) site and an active (DNA-binding) site. The conserved N-terminal domain contains a winged HTH motif that mediates DNA binding, while the C-terminal domain binds coactivating, toxic compounds. BmrR shares the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	4.76517e-26
NZ_LN774771.1\|WP_047916779.1\|38597_38933_-\|Cd(II)-sensing-metalloregulatory-transcriptional-repressor-CadC	gnl\|CDD\|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	2.16667e-15

>NZ_LN774771.1|WP_047916778.1|35572_37696_-|cadmium-translocating-P-type-ATPase
MSKASKQTTYRVDGLSCTNCAGKFEKNVKNISGVTDAKVNFGAGKISVYGESSISQIEKAGAFENLKISPEKDYSNTPLKKESFLKKNWHLVVSVVFILLAFISQNISGEDSTITIALYVVAIIIGGFSLFKEGISNLLKLDFTMESLMTIAIIGASIIGEWAEGSIVVILFALSEVLERYSMDKARQSIRSLMDIAPKEALIRRNNVEQMITVSDIQIGDIMIIKPGQKIAMDGVVIKGYSAINQSAITGESIPVEKKVNDEVFAGTLNEEGLLEVKVTKHVEDTTISKIIHLVEEAQGERAPAQAFVDKFAKYYTPTIMLIALLVVVVPPLFFGGDWDTWIYQGLSLLVVGCPCSLVISTPVSIVSAIGNSAKNGVLVKGGIYLEEIGGLQAIAFDKTGTLTKGKPVVTDFIPYSEHMNEQKSLSIITALETLSQHPLASAIISKAMVDNVDYKSIQIDNFSSITGKGVKGDIDGITYYIGSSKLFKSSLENSQSISQTYQSLQKQGKTAMLFGTESNILAIIAVADEVRESSEEVIAQLHKLGIAHTIMLTGDNNDTAQFIGKEIGVSDIKAELMPEDKLTYIKELKQTYGKVAMIGDGVNDAPALAASTVGIAMGGAGTDTALETADVALMGDDLKKLPFIVNLSRKTLKIIKQNITFSLGIKLLALLLVLPGWLTLWIAIVADMGATLLVTLNGLRLMKVKK
>NZ_LN774771.1|WP_047916777.1|34229_34910_-|IS6-family-transposase
MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCHTTIYRWVQEYSKVLYYLWKEKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLHKQFGEPKSIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETLRGMYKKNRRNGTLFGFSVSTEIKVLMGIPA
>NZ_LN774771.1|WP_047916776.1|33147_33912_-|(S)-acetoin-forming-diacetyl-reductase
MVKVAIVTGAGQGIGHAIAQRLHKDGFKIGIIDYNSETANAAVAKFPDGDAFAAVADVSKRNQVFDAFDKIVGHFGDLHVVVNNAGVAPTTPLDTITEDQFINTFSINVGGTIWGSQAAHKYFKEFGHGGKIINAASQAGVLGNPNLTIYGGTKFAIRGITQTLARDLAEEGITVTAYAPGIVKTPMMFDIAHQVGKNAGKDDEWGMQTFAKDIALKRLSEPEDVANAVAFLAGPDSNYVTGQTLVVDGGMVFH
>NZ_LN774771.1|WP_014727478.1|32358_33039_+|IS6-like-element-ISS1N-family-transposase
MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCHTTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETLRGIYKKNRRNGTLFGFSVSTEIKVLMGIPA
>NZ_LN774771.1|WP_047916774.1|29753_31517_+|oleate-hydratase
MRYSNGNYEAFARPRKPKNVDQKSAYIIGGGLAGLATAVFLVRDGHMSGEKIHIYEELPTPGGSLDGEKRANIGFVTRGGREMENHFETMWDMYRSIPSLEIKDASYLDEFYWLDKDDPNSSNTRLIYNRGQRVPTDGLYTLDKKSKELIDLVLTPESKLGKTTIEEFFSNEFFESNFWMYWATMFAFEKWHSAVEMRRYTMRFIHHIDGLPDFSALKFNRYNQYDSMVLPIIKYLESYNVEFIYNTQVNNVVVDFENDEKIAKKLVIQDGDDVSLSRDDLVFVTNGSITESSTYGSHDKPAPISKELGGSWSLWKNLAEQSNDFGHPEVFYDNLPEKSWFVSATATIKTPEIEPYIERLTNRDLHDHKINTGGIITITDSNWLMSFAIHRQPHFKEQKENETTVWIYGLYSDTKGNFVDKTIVESSGEEITQELLYHLGVPESKIKQLSNQNNVNTVPVFMPFITSYFMPRIAGDRPDIVPKGSVNLAFIGNFAESPSNDTVFTTEYSIRTAMESVYTLLEVERAVPEVYGSIYDIRELLKAIYYMGDKKTIDEANLGIPKLAKVALKKKIKGTFIEELLKESKLL
>NZ_LN774771.1|WP_047916773.1|28257_29418_+|restriction-endonuclease-subunit-S
MSKKSPQLRFEGFTDDWEERKLGEIGSFKNGMNFGKDAMGHGSPFVNLQNIFGKNIVDDTTLELAESTEKQKVEYSLIKGDVLFIRSSVKPSGVGEAALVDSNLPDTTYSGFIIRFRPKIDIDNNFKRFAFGTKYVRNQIMARATSSANTNINQDSLSLIQVGLPNLKEQEKIGSFFKQLDATIALHQRKLDLLKEQKKGFLQKMFPKNGEKVPELRFAGFADDWEERKFKDILKTHSFRSYLAGVSENGEYEVIQQGDKPIVGYSDGEPFTDYKDVTLFGDHTVSLYKPKSPFFVATDGVKILSADNFEGNYLYTTLERYKPEPQGYKRHFTILKNQDVWFTENMEEQQKIGSFFKQLDETIDIHQHKLDLLKEQKKGFLQKMFV
>NZ_LN774771.1|WP_047916772.1|26669_28265_+|type-I-restriction-modification-system-subunit-M
MATGLNQQLWASADILRGKMDASEYKNYLLGLIFYKYLSDAQLREVYEQENGKTDTFPERSTQYAGFMEWYEEDKDDLIENIQPKQGYFIQPDQLFYHYRIKADNYEFNLTDLQAGFNELERQGEEFSGLFADIDLNSTKLGSNAQQRNVTITEVLRALDEIDLFEHNGDVIGDAYEYLIGMFAAGAGKKAGEFYTPQAVSRIMSEITSIGQETRAPFHIYDPAMGSGSLMLNIRRYLKNPNQVHYHGQELNTTTFNLARMNLILHGVDKERMNLNNGDTLDADWPSEEPYQFDSVVMNPPYSAKWSAADKFLSDPRFERFGKLAPKSKADFAFLLHGFYHLKESGTMGIVLPHGVLFRGAAEGTIRQSLLEMGAIDAVIGLPANIFFGTSIPTTVIILKKNRSRRDVLFIDASQDFEKQKNQNVLLDEHIDKIVSIYKKREDIERYAHVASFDEIQENDFNLNIPRYVDTFEEEEPVDLVAVNTNLLKVNEELVQQDQTLLSLINDFSESEENQALIDSMRLLLRGGHDE
>NZ_LN774771.1|WP_047916771.1|23592_26670_+|type-I-restriction-endonuclease-subunit-R
MSHSEQMIENQFIQILSEKENQWTYRPDLKSEEALWQNFRGHLNRINLAVLEEQLLTDKEFKQVKVEFSRLTGTPFLASQWLRGENGVAQVLLEREDGKKVTLEAFRNKDISGGTSSYEVVHQVVPDSSRVDRGDVSLLINGLPIIHIELKKESAKDGFMQAYYQIQRYAEDGFFKGIYATTQIMVISNKVDTRYFARPSEDTAEAYAQMKKFLFNWRTEDNQTVSDLFDFTRTVLRIPDAHELISQYSILVDDQKNQKFLMVLRPYQIHAIHKIRQKAAQHEGGFIWHATGSGKTITSFVATKLLAQNAIGVDRTVMVVDRTDLDAQTQDEFTKFASEYHTGQTTGNSVANTLIVGIKNQKQLARNLLSSKNNNTILVTTIQKLSAAMRSAQQESEEKGSNQFEKLRQEHLVFIVDEAHRAVSDEEMKRIKKILPNSTWFGLTGTPIFEENKKQENGTFARTTSQQYGPLLHSYTTKNAMDDGAVLGFQVEYHSLVSEEDQEVIVTQLNKGKLPDDALQQEKLLPTELYETDEHIRTMLQKIFNRRSVVKKFKVKNGFPTMSAILTTHSIAQAKHIYRILKEMKDNGTLLNGRQFDERHQLIDKDFPRVAITFSTNPDQLEKNEQDDELVEIMKEYAKQFDASPYQDEKLYNQNINKRLARKEKQYQSDGQWLDFVIVVDRLLTGFDSPTIQTLYIDREMNYQKLLQAFSRTNRIYTGKDSGLIVSFRKPFTMKENVQNTFRLFSNENQNFDQLIPREYEEVKKEFIECSTLYKQSEADLSDNPNDLKTMIAQVSAYQKLEKSYKALRSYDQYEEDFEAFSEVVEQLPQYQGKTENVKTKIKEMIEDEEHPEEDFEKLLQEIAFSSQLNATHKDVVNSFYINQLLKAIQLNEAGAVEKFEKEIQQKDPQIQKMYHTLKDQLVNTTEEIDVAQLKETSIQNEIQRQLQKEAEEFGLSFEFLQSAMNEYQGDKKTIPYLTHLLDSMTLSKEEFEAKTGEKYRRRTKVLEERLQQNFEQIQKWKEEL
>NZ_LN774771.1|WP_031367156.1|23207_23576_+|hypothetical-protein
MKSTSNSGILDIIEYQKEQIKDLQNTKDEQFKQLSNMQNLLDQQQRQALQDKKVLEEYKSEINELKALKMPQEDMKDGSSIRGEAQEEIERQKAQLKLSEEERNKAKEKDPVKTESKKWWQL
>NZ_LN774771.1|WP_047916770.1|22250_23141_-|IS982-family-transposase
MTYNSTLTKVFVYLLTSIEAIYQTSVPLEIQNRKNVHLATSDCLVITCYLWGVLHFSETLKAKHQLAQSLFPNFLEYSRFVRRCNALLPSIQLIRQALVFKEVEGIDVSIIDSFPIPLCQPIRNFRSKVLGDYANIGYNATKGQYFYGCKCQALVSESGYVIDYTITPASMADSSMTEEVLSQFGTPTVLGDMGYLGQSLHDRLELKGIDLITPVRKNMKQKKILFPNFSKRRKVIERVFSFLTNLGAERCKSRSPQGFQLKLEMILLAYSLLLKSAKSLEPETLRYSIGYQVMAK
>NZ_LN774771.1|WP_099046847.1|37922_38426_+|signal-peptidase-II
MLNGKIISKQNLLLLGIMISAVLIDQLSKIWLTSTLQIGESIELIPSFFKITYAQNTGAAWSVLEGHMTFFYVVTIIALILLGWYFKNLKDYQIVQKIGVILMIAGTLGNFIDRLLFQFVRDSLDFRILDYNFPIFNIADILLVSGVFLLIIDETIKTFNIRSKLKK
>NZ_LN774771.1|WP_047916779.1|38597_38933_-|Cd(II)-sensing-metalloregulatory-transcriptional-repressor-CadC
MNDICEITCFDEEKVQKIQTSLVDKKLYDISQIFKALSEETRLTIAYALTLEKELCVCDISIIVNSTVATTSHHLKILSKAGVVQNKKVGKMVYYSLNNSLVERLIKDIVL
>NZ_LN774771.1|WP_082095493.1|40385_40619_+|hypothetical-protein
MAHFVSKYLTLVQIELKHIFDHFYRIDKSRTRKSGGVGLGLAIVKQITELHEGRIFVNSKLNCGTEIQIIIPSKKTH
>NZ_LN774771.1|WP_047916780.1|40744_40981_+|hypothetical-protein
MSVTKLLAKIDGISLFTGNIIPSKKLLEVEGIIKTALLNDDILEIIYESDILKLYRINESLREIDLRVSYYFNNKKMY
>NZ_LN774771.1|WP_039670417.1|41030_42320_+|CHAP-domain-containing-protein
MNKKFTSLLLLSSVILITTADKTRTKADTTDSSIEQQENIINEAQSAKDKSLSDISLLQSKIDGIRVEKNKTEQKISEIKKQAQNLNNKIEELSKNIEKRTDVLESQARSAQVNSNATNYVDTIVNSKSLSDIIQRLSAMATISSANKSMLSLQIKEQKDLNNKSDEVKKNYIEYDNLVKNQALQEKDLTSQEKQLKVASLNYQSTIETAQDKKENLLKQKSTAEKEAKIAQAEKEKVASAQKSAKEAYTSNSVTNTPSSSVEKSSSPKKENTITSSNTGTTVEQGTSTSSNNDSNNSTSGTGNPNYNPYAGGGCTDFVWQYFAAKGIYIANIVNGNGGYWGTNGVSQGVLRRTNLAPGVIASGFTDHFTGYGTSTTARTSPYGHVAVVTGVNPDGTFNVQEAGYGGTFPWGNVRTNISPENVVFLLPN
>NZ_LN774771.1|WP_039670418.1|42372_43152_-|MerR-family-DNA-binding-transcriptional-regulator
MENKNYLTIGKLSSYSGIHIKALRYYESIGILHPALIDANNGYRYYSHAHIPYVKIIKLCADYGIPLGTFNDFIKSETEINLIKIIRKASNILELKEKQLKEDKQFLEYIQNEISLSQKLDSSINVDLEQTHEDFILIPFDDVFFSNKYYDTINKTISMLKDLEIEFFNRIGCYYSLQYGNYDKFLALKVRGHSSKLKNIKILHIDHVCVQAQHIEPDKITDELIRLKKLKQNSILILETYENPYNFSTPHLELRILLN
>NZ_LN774771.1|WP_003134160.1|43242_45147_+|heavy-metal-translocating-P-type-ATPase
MKSLITALKEKRALRLYFIGIIIFIIGLLLPISSTVRVLISIIATILSGYHVMLEGIDDTIKETVKKKRFTPNTHILMTLAAIGAIFLGEAVEAALLIFIFAGAHFLEEYVEGKSKREITKLIELNPTEARLINNEGNIEVVSIDKLKIGDRLQVLNGAQVPTDGIILNGSTSIDESTINGESIPREKNVGDIVFGSTINGTGTFTMRVSKDSKDTVFSKILTMVEESQNNLSPTADFIKRFEPHYVNGVLVIFLALIIFSPMFLGWTLTETISRSLVFLVSASPCALAVAAIPATLAGISSLAKQGILFKGGNFLSNLINLKAVAFDKTGTLTEGKPKVVDFYFNPELDGESFRNTLVAMEKQSNHPLANAIVNKFEIQKVDYDIKVENELGTGLSATYQGESYRIAKPSAFKIVSQEWIEKQENFENEGKTVVFIAVNDKVEGLIAIQDTPQKTAISAIQYLNKNQIKTIMITGDAVLTGKAIGKQLGVRDVQANVMPDEKAKIINENKEKYGPTAMIGDGVNDAPALAVADVGIAMGDGTDVAIETADVVLMNNDLGNFVSAHKTSKRLKNIVTQNIIFALLVVLFLVYISLWKNTSVVLSITLHEGSTLVVLLNSLRLLLPNKKDIEGEL
>NZ_LN774771.1|WP_039670419.1|45147_45495_+|hypothetical-protein
MFKNIFQNLTEQAQEILGNITENIPEQIQNVAGGITENIPEQIQNVAGGITENIPEQIQNVAGGITENIPEQIQNVAGGITENIPEQIQNVAGGITENIPEQIQNVADSITKFLG
>NZ_LN774771.1|WP_047916781.1|45704_45905_+|hypothetical-protein
MFSIEVGIKVGIKVSIEVGIRVSIRVGIKVSIKVSIKVSIRVSIRVGIKVSIEVGIRVGIEKCYRP
>NZ_LN774771.1|WP_047916782.1|45912_46287_-|Hg(II)-responsive-transcriptional-regulator
MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYDDVKRVGFIKRIQELGFSLSEIYKLLGVVDKDEVRCQDMFEFISKKQKEAQKQIEDLKRIEMIYIFPKKFAFSQNMAINNC

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LN774771_1	1.1\|37741\|28\|NZ_LN774771\|CRISPRCasFinder	37741-37768	28	NZ_LN774771	Lactococcus piscium MKFS47 plasmid III, complete sequence	37741-37768	0	1.0
NZ_LN774771_1	1.1\|37741\|28\|NZ_LN774771\|CRISPRCasFinder	37741-37768	28	AP013442	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C22-MedDCM-OCT-S36-C18	25210-25237	5	0.821
NZ_LN774771_1	1.1\|37741\|28\|NZ_LN774771\|CRISPRCasFinder	37741-37768	28	AP014433	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S41-C103, * SEQUENCING IN PROGRESS *, 6 ordered pieces	20367-20394	5	0.821
NZ_LN774771_1	1.1\|37741\|28\|NZ_LN774771\|CRISPRCasFinder	37741-37768	28	NZ_CP028874	Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence	47837-47864	6	0.786
NZ_LN774771_1	1.1\|37741\|28\|NZ_LN774771\|CRISPRCasFinder	37741-37768	28	NZ_CP053316	Bacillus circulans strain GN03 plasmid unnamed, complete sequence	59347-59374	6	0.786
NZ_LN774771_1	1.1\|37741\|28\|NZ_LN774771\|CRISPRCasFinder	37741-37768	28	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	80642-80669	7	0.75

1. spacer 1.1|37741|28|NZ_LN774771|CRISPRCasFinder matches to NZ_LN774771 (Lactococcus piscium MKFS47 plasmid III, complete sequence) position: , mismatch: 0, identity: 1.0

tttacaaatatataataacagattaaag	CRISPR spacer
tttacaaatatataataacagattaaag	Protospacer
****************************

2. spacer 1.1|37741|28|NZ_LN774771|CRISPRCasFinder matches to AP013442 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C22-MedDCM-OCT-S36-C18) position: , mismatch: 5, identity: 0.821

tttacaaatatataataacagattaaag	CRISPR spacer
attaccaatatataataacagtttaatt	Protospacer
 **** *************** ****

3. spacer 1.1|37741|28|NZ_LN774771|CRISPRCasFinder matches to AP014433 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S41-C103, *** SEQUENCING IN PROGRESS ***, 6 ordered pieces) position: , mismatch: 5, identity: 0.821

tttacaaatatataataacagattaaag	CRISPR spacer
attaccaatatataataacagtttaatt	Protospacer
 **** *************** ****

4. spacer 1.1|37741|28|NZ_LN774771|CRISPRCasFinder matches to NZ_CP028874 (Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence) position: , mismatch: 6, identity: 0.786

tttacaaatatataataacagattaaag	CRISPR spacer
ggtataaatatataataacagatactag	Protospacer
  **.******************   **

5. spacer 1.1|37741|28|NZ_LN774771|CRISPRCasFinder matches to NZ_CP053316 (Bacillus circulans strain GN03 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

tttacaaatatataataacagattaaag	CRISPR spacer
aatttaaatatataataaccaattaaag	Protospacer
  * .************** .*******

6. spacer 1.1|37741|28|NZ_LN774771|CRISPRCasFinder matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 7, identity: 0.75

tttacaaatatataataacagattaaag	CRISPR spacer
gttacaaatatataataaaagaaaattc	Protospacer
 ***************** ***  *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_LN774769

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_LN774769_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN774769_1

2298001-2298087

Orphan

Consensus_repeat	Method
TCAATTCAAAAGAAGCTTAGGCTTCTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LN774769_1

>merge|NZ_LN774769|1|2298001-2298087|CRISPRCasFinder
TCAATTCAAAAGAAGCTTAGGCTTCTTTTTTGTCGTAACACGATGTGTTACTGATTGGTCAATTCAAAAGAAGCTTAGGCTTCTTTT

>NZ_LN774769|1|1|2298001-2298087|CRISPRCasFinder
TCAATTCAAAAGAAGCTTAGGCTTCTTTT	TTGTCGTAACACGATGTGTTACTGATTGG
TCAATTCAAAAGAAGCTTAGGCTTCTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN774769.1\|WP_047916374.1\|2288935_2289871_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133039
NZ_LN774769.1\|WP_047916390.1\|2314247_2316323_-\|elongation-factor-G	unknown	unknown	gnl\|CDD\|234569
NZ_LN774769.1\|WP_047916377.1\|2292031_2293081_-\|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224013
NZ_LN774769.1\|WP_047916684.1\|2293244_2293838_-\|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl\|CDD\|224810
NZ_LN774769.1\|WP_047916383.1\|2299699_2300119_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|214628
NZ_LN774769.1\|WP_047916387.1\|2304747_2305236_-\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674
NZ_LN774769.1\|WP_047916389.1\|2313197_2314010_-\|pur-operon-repressor	unknown	unknown	gnl\|CDD\|236414
NZ_LN774769.1\|WP_047916373.1\|2288150_2288939_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224596
NZ_LN774769.1\|WP_167594969.1\|2303708_2304653_-\|PDZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|226011
NZ_LN774769.1\|WP_047916382.1\|2299066_2299606_-\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238496
NZ_LN774769.1\|WP_047916375.1\|2289860_2291003_-\|DUF1972-domain-containing-protein	unknown	unknown	gnl\|CDD\|340858
NZ_LN774769.1\|WP_047916372.1\|2286941_2288150_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224057
NZ_LN774769.1\|WP_047916384.1\|2300125_2300644_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240049
NZ_LN774769.1\|WP_047916388.1\|2305228_2305780_-\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl\|CDD\|367574
NZ_LN774769.1\|WP_047916385.1\|2300850_2303451_-\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|237515
NZ_LN774769.1\|WP_047916379.1\|2294960_2296691_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|179877
NZ_LN774769.1\|WP_047916380.1\|2296836_2297874_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_LN774769.1\|WP_047916378.1\|2293839_2294715_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274
NZ_LN774769.1\|WP_050703061.1\|2312573_2312966_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153234
NZ_LN774769.1\|WP_047916376.1\|2291180_2292035_-\|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl\|CDD\|367904

Protein	Function_ID	Function_description	E-value
NZ_LN774769.1\|WP_047916374.1\|2288935_2289871_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133039	cd04196, GT_2_like_d, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	3.00419e-82
NZ_LN774769.1\|WP_047916390.1\|2314247_2316323_-\|elongation-factor-G	gnl\|CDD\|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NZ_LN774769.1\|WP_047916377.1\|2292031_2293081_-\|dTDP-glucose-4,6-dehydratase	gnl\|CDD\|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_LN774769.1\|WP_047916684.1\|2293244_2293838_-\|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl\|CDD\|224810	COG1898, RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane].	3.62522e-52
NZ_LN774769.1\|WP_047916383.1\|2299699_2300119_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	6.47812e-18
NZ_LN774769.1\|WP_047916387.1\|2304747_2305236_-\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	4.27318e-66
NZ_LN774769.1\|WP_047916389.1\|2313197_2314010_-\|pur-operon-repressor	gnl\|CDD\|236414	PRK09213, PRK09213, pur operon repressor; Provisional.	6.25784e-155
NZ_LN774769.1\|WP_047916373.1\|2288150_2288939_-\|ABC-transporter-permease	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.97413e-48
NZ_LN774769.1\|WP_167594969.1\|2303708_2304653_-\|PDZ-domain-containing-protein	gnl\|CDD\|226011	COG3480, SdrC, Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms].	2.72671e-108
NZ_LN774769.1\|WP_047916382.1\|2299066_2299606_-\|cysteine-hydrolase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	5.56241e-54
NZ_LN774769.1\|WP_047916375.1\|2289860_2291003_-\|DUF1972-domain-containing-protein	gnl\|CDD\|340858	cd04955, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in certain bacteria and Archaea.	3.71277e-177
NZ_LN774769.1\|WP_047916372.1\|2286941_2288150_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224057	COG1134, TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	7.30268e-106
NZ_LN774769.1\|WP_047916384.1\|2300125_2300644_-\|NUDIX-domain-containing-protein	gnl\|CDD\|240049	cd04693, Nudix_Hydrolase_34, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.99699e-45
NZ_LN774769.1\|WP_047916388.1\|2305228_2305780_-\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl\|CDD\|367574	pfam03602, Cons_hypoth95, Conserved hypothetical protein 95.	2.56161e-77
NZ_LN774769.1\|WP_047916385.1\|2300850_2303451_-\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	gnl\|CDD\|237515	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional.	0
NZ_LN774769.1\|WP_047916379.1\|2294960_2296691_-\|hypothetical-protein	gnl\|CDD\|179877	PRK04778, PRK04778, septation ring formation regulator EzrA; Provisional.	0
NZ_LN774769.1\|WP_047916380.1\|2296836_2297874_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	2.80001e-131
NZ_LN774769.1\|WP_047916378.1\|2293839_2294715_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_LN774769.1\|WP_050703061.1\|2312573_2312966_+\|hypothetical-protein	gnl\|CDD\|153234	cd03140, GATase1_PfpI_3, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	2.01047e-12
NZ_LN774769.1\|WP_047916376.1\|2291180_2292035_-\|dTDP-4-dehydrorhamnose-reductase	gnl\|CDD\|367904	pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhamnose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhamnose, is synthesized by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.	2.24367e-125

>NZ_LN774769.1|WP_047916380.1|2296836_2297874_-|elongation-factor-Ts
MAITAAQVKELREKTGAGVMDAKKALVETDGNIEKATELLREKGMAKAAKKVDRIAAEGLTGVYVDGNFAALVEVNSETDFVAKNEQFVALVNESAELIAKNKPADNDAALAIKMVSGKTLSEAYVEATSTIGEKISFRRFALIEKTDAQHFGAYQHNGGRIGVITVVDGADDALAKQVSMHIAAMKPVVLSHTELEEQFVKDELAQLNHVIELDNESRAMVDKPALPFLTYGSKAQLTDEIVAAAEVAIKAELAAEGKPEKIWDKIIPGKMERFMLDNTKVDQAYTLLAQLYVMDDSKTVEQYLASVNATVVAFARFEVGEGIEKAANNFEAEVQATMAAALEK
>NZ_LN774769.1|WP_047916379.1|2294960_2296691_-|hypothetical-protein
MPKSIIIAIIILLAVVVIFYAIAMVLRKQTENRILALEKRKEDLFDLPVQEEVDAVKKLHLVGQSQTIFREWNQKWIDLSANSFADLENHIFEAEQLNDSFRFIRARASVDASEGQIKLMEEDVLSIRDGISELTKQETINSSKIQDSLDLYDTLRSEIADNAGKYGVAITELQVQLKNIETEFTQFVDLNSTGDPIEASEVLETAEEHTIALGAIADRIPALVEELTQTYPAQLEELTEGYEAFKAQDLKLPDSAKVDDRLQEISDDLAQAMIFLENFELDRADAQLEKMKLNLDGLYEVFSDEYKARRDVANNAAIIKDYLAHTRTNNKNLLLEIDHVSQNYILTGNEMGLVRGFQEELETLDSGVSEILDVIKENAQPYSLLGKEVDIIISTLDDIEKNQVKISSDLQNLRKQEKAAQDVADTFDREIRILKRYVEKRNLPGLPQAYLDKFFATSERVQTLFKELNKVKVNIDGVNHLVDVATEDVANLKDATDEMVDKARLAEDLMQYGNRYKTTNERVAKSIARAYQLFERDRNYAASFEEISVTLDEVEPGASERISNVYYNTKPTPDYR
>NZ_LN774769.1|WP_047916378.1|2293839_2294715_-|glucose-1-phosphate-thymidylyltransferase-RfbA
MTKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLAGIKDILIISTPQDVPRFEELLGDGSEFGISLSYAVQPSPDGLAQAFIIGADFIGDDNVALILGDNIYYGPGMSSMLARAAAKDTGATVFGYQVKDPERFGVVEFDKDMRAISVEEKPEHPKSNYAITGLYFYDNDVVEIAKSIQPSSRGELEITDVNDAYLKRGDLDVEVMGRGFAWLDTGTHESLLEAAQYIETVQRMQNVQVANLEEIAYRMGYITRDQVIELAQPLKKNEYGQYLLRLVEADV
>NZ_LN774769.1|WP_047916684.1|2293244_2293838_-|dTDP-4-dehydrorhamnose-3,5-epimerase
MSEDFFGKTLAVREISEIPGMLEFDIPVHGDNRGWFKENFQKEKMMPLGFPTSFFAAGKLQNNVSFSRKDVLRGLHAEPWDKYISVADNGRVLGAWVDLREGASFGHVYQTEINASKGIFVPRGVANGFQVLSEFVSYSYLVNDYWALELKPKYAFVNYADPALGIKWEDVANAEVSEADINHPLLSDVKPLSADSL
>NZ_LN774769.1|WP_047916377.1|2292031_2293081_-|dTDP-glucose-4,6-dehydratase
MTELKKIIVTGGAGFIGSNFVHYVYNNHPEIEKIIVLDKLTYAGNKANISDILGDRVELVVGDIADANLVDELAEKVDAIIHYAAESHNDNSLKSQDEFIHTNFIGTYTLIQAARKHDLRFHHVSTDEVYGDLPYREDLPGHGEGAGEKFTDRTPYNPSSPYSSTKAASDLIVRAWVRSFGLKATISNCSNNYGPYQHIEKFIPRQITNILSGSRPKLYGDGKNVRDWIHTEDHSSGVWAILTKGQIGETYLIGADGEKNNKEVLEEILTEMGQDATAYDRVTDRAGHDLRYAIDNTKLRTELGWTPKHTDFESGLKETINWYSDNAAWWQAEKAAVEANYAKSQEVLK
>NZ_LN774769.1|WP_047916376.1|2291180_2292035_-|dTDP-4-dehydrorhamnose-reductase
MILITGASGQLGTELRYLLDERGEDYVATDVAELDITNAKQVNQVFDEVKPTLVYHCAAYTAVDKAEDEGKALDYAINVTGTENIAKATAAHNATLVYISTDYVFDGLKPVGEEWEVDDLPDPQTEYGRTKRLGEELVEKYADKFYIIRTAWVFGNYGANFVFTMQKLAETHAALTVVNDQHGRPTWTRTLAEFMTYLTENQRDFGYYHLSNDASEDVTWYDFAVEILKDTAVTVSPVDSSQFPAKAKRPLNSTMSLDKAKATGFVIPSWQDALNAFYRQEKPV
>NZ_LN774769.1|WP_047916375.1|2289860_2291003_-|DUF1972-domain-containing-protein
MQHVFIIGSRGLPAKYGGFETFVEELVSHQQSDQIKYHVAQLSDSETGKHLTYKTADVFEVKVRNFGAANVIFYDRDAIIYAIRYIKANNITNPIFYILGNTLGAFIGHYVKLIHKIGGKLYVNPDGLEWKRSKWIKPIQVYLKYSEKKMAENADLIISDNQGIEDYLKAEYDHVTSKVIAYGTNDVVMAPGVAQPWLDKYGIQVGAYYLVVGRFVPENNYEVIIRNFMNSSTTHDLVIITNHLDDPYFEKLRQLTNFDQDKRIKFVGTVYDKEQLTAIRKHAFAYIHGHAVGGTNPGLLEAMSVTDLNLVFDVSFNRNVALDSALFWQIDTLTEVMSQAEMLKVEAIEGLAKKAKKIIAEKYTWDKIVDQYEELFLNES
>NZ_LN774769.1|WP_047916374.1|2288935_2289871_-|glycosyltransferase-family-2-protein
MKVNIVLSTYNGAKFLSEQIDSIQAQTFTDWQLLIRDDDSRDKTRDIIVSYMLKDERIKFINEGDHTNLGVINSFYKLIKHDSADYYFFCDQDDVWLPEKMATMLAEATRHDASQPLMVYMDLSVVDEKLKVISPSMVHSQSHHANTSLLAELTENTVTGGVAMINHALVKRWRSTDNIIMHDWYLALLASATGELVYIDKPGELYRQHDHNVLGARTFGKRLKKWLNPLQAVDKYWHLIITSQKQAASLLTQPDLSDENRELIEKYVALLNQTVVNRIKYLKEYNFKKNKLFHTIVFRTLVVTKLGYVKK
>NZ_LN774769.1|WP_047916373.1|2288150_2288939_-|ABC-transporter-permease
MNSKNWILLKELVKTDFKLRYQGSLMGHLWSILKPLMLFSVMYLVFVRFLGLGRDMPHFAVALLLGMVIWNFFAETTSMGLTSIVGRGDLLRKLSFPKEIIVLSVAVSAFINFLINLLVVLFFAVLNQVEISKYAIIAPLYIIPIFAFSLGIAFILATLFVYFRDIAPVWEVVMQAGMYATPIIYSLSMIHNNKIIAVMMLNPLATIIQDLRHILIYPGNQVITEFINNKWIVAIPYVLPFIVLVFGYTIFKKYADKFAEII
>NZ_LN774769.1|WP_047916372.1|2286941_2288150_-|ABC-transporter-ATP-binding-protein
MNKKIEEKESVVVVKNVSKSFKLPTESSTSLRTTLVNRMKGIKGFKKQSVLKDISFNVEKGDFFGIVGRNGSGKSTLLKIISQIYVPETGTVSINGRLVSFIELGVGFNPELTGRENVYLNGAMLGFSAKEVDDMYGDIVSFSELHDFMDQKLKNYSSGMQVRLAFAVAIQAKSDILVLDEILAVGDEAFQRKSREFFEEIKRDVNKTVILVTHDMNAVQRYCNKVIYIKDGVLEKSENLQDITNQYSEDNLENYESQVGTGKAPAKDKAKIWIEKKSNSVLSNSDKLFEFEMHYELYDEKLKKETPLYIAYALHDEKRGGIVFDSGSIAVDSSGLRASIPLDNFHNTDFKIIASLRKDPKIVNQENPNETDMITFTKEGHDARFILRDIEDKEDYGLLREI
>NZ_LN774769.1|WP_047916382.1|2299066_2299606_-|cysteine-hydrolase
MKQGLLVIDVQNDYFTGGKMTLTGADEALLKINALEERFRAEKLPIIYIQHIKYEPNADFFEVGTVGADLHPQLKHDASSIIVEKHFPNSFQSTPLQQQLEKNGVEQLVICGMMTHMCIRATTPVAESLGYAPIVISDATATRDLIVNDELMPAKQVQETMLAELSAVASLMTTNEFLA
>NZ_LN774769.1|WP_047916383.1|2299699_2300119_+|winged-helix-turn-helix-transcriptional-regulator
MKGISLDNIDHQILAYLKSNAKLTNKDIGQLIHMTGQAVGIRINKLIDAGQIQNYTISIQYDHKQFIRVFMDNNQYDTFEAAVNSYLEVADFYKVSGQACYMIVGHFSHKKLAQFITTISKWGRYSIETVLDNRKKERQ
>NZ_LN774769.1|WP_047916384.1|2300125_2300644_-|NUDIX-domain-containing-protein
MELFDIYDQERRLTGRTAERGTKLSVGDFRLVVNLSILNSDNQLLIQQRQPFKEGWPNMWDISAGGSAIAGETSQEAIARETQEEIGLQHDFSEMRPFFTLNFDEGFDDYYMLYQNITLSELKLQTSEVQAVKWATREVVQALILSGEFIPYHKSVIDLLFDLNGVYGGHDL
>NZ_LN774769.1|WP_047916385.1|2300850_2303451_-|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase
MATKTVDKTETFDVAGMIDELAAKGAQALKGLEKLNQEQIDHIVHEMSMAALDKHMPLAKLAVEETGRGIYEDKAIKNMYASEYIWNAIKDNKTVGVINEDKEAGIIEIAEPVGVICGVTPTTNPTSTTIFKAMIAIKTRNPIIFAFHPSAQKSSSAAAQIVLDAAVAAGAPENCVQWVTKPSIEATGLLMNHPTIATVLATGGSAMVKSAYSTGKPALGVGPGNTPAYITREAKIKRAVNDLFLSKTFDNGMICASEQAIIVDNEVFNEVKDEFLAHNAYIVSSKSELAKLEATVMLPDGHAVNPKIVGFSAKHIAELAGIKVPAETKLLIAEIAGVGPDYPLSREKLSPVLAMIKANSTEEGLDLCEAMLDLGGLGHTAVIHTEDEALQIEFGIRMKACRILVNTPAAEGGIGNIYNEMLPSLTLGCGSYGHNSVSHNVSAVDLINVKTLAKRRNNMQWFRLPPKVYFEKNSITYLQQIKAERVMLVCDPGMVQFGYADLIRKQLEKNPNDPSIEVFSDVEPNPSTNTVYKGLEMFNNFQPDVVIALGGGSAMDAAKGMWMFFEHPDTSFFGAKQKFLDIRKRAYKIEYAEKAKFICIPTTSGTGSEVTPFAVITDSDDHTKYPLADYALTPDVAIIDPQLVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSLQAIKIVFEYLEKSVKTGDAESREKMHNASTMAGMAFANAFLGISHSIAHKVGGAWGVPHGRTNAILLPHVIRYNAKDPQKHAMFPKYDFFRADTDYADIARFLGLKGNTTAELVEALASAVYKLGIATGIEMNWQSQGLTKKQMVAEIDHLAEKAYEDQCTTANPKQPLISELKAIIEIAYDYKG
>NZ_LN774769.1|WP_167594969.1|2303708_2304653_-|PDZ-domain-containing-protein
MPGTTENVGSMVKVDQASIVGKGSLNLTTVSMMQATGAGLIYAAATDFTDVYSKKDMMGNQSDSDYNRMNAFYMESAQNAAIYEAFKLANKPFELTYKGVYVLDVMQASSFKNVLQVADTVSGVDGKKFKSSQELMSYIKSLKVGGPISVQYTNDQGKNKSADGKTIKLADGKAGIGITLVDHTVVSSTPTVTINAGGIGGPSAGMMFTLEIYSQLTGKDLTQGKDIAGTGTIEANGIVGRIGGIDKKVATANQNGAKVFLAPDDQITPEMKKYDKHIKTNYQEALDAAKKLKTKMKIVPIKTVQYAINYLENN
>NZ_LN774769.1|WP_047916387.1|2304747_2305236_-|pantetheine-phosphate-adenylyltransferase
MTKKIGLYTGTFDTVTNGHLDIIYRAAKLFDTLYVGIFNNDKKNPLFSTIERKVMLENLLLDFDHVQVIVHESDLTVNVAEELQVTALVRSVRNVQDLAYESEMVYFNQQMSGIETIILLADPNLQYINSTRIKELGKFGADISKWVPSLVIKELERKIEKK
>NZ_LN774769.1|WP_047916388.1|2305228_2305780_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MRVVAGNYGGRNLKTLDGKLTRPTGDKVRAAMFSMIGPFFDSGRVLDLYAGSGGLAIEAISRGMSSAVLVERDRKAQAIILDNIEMTKELNKFSLLKMDARHALNQLSGPFDLVFLDPPYAKETVENDISSLDSLQVLSDRVIIVCETDESVVLPDSIGEFEIIKQKRYGISKVTIYERGDHD
>NZ_LN774769.1|WP_050703061.1|2312573_2312966_+|hypothetical-protein
MIGINNRPIKTAGGLKIIPDCTVSEIDISADTVLLLAGADTWHDKKHKDILSLTEKVLLENGTVVSMCASVGALNSLGILATRALLVAYTLVTKFNIIDPDILDAWYHYYKMSDLQYYYRLQALFMQKIQ
>NZ_LN774769.1|WP_047916389.1|2313197_2314010_-|pur-operon-repressor
MKRSERLVDFTNYLLNHARKLTTLSFFSERYGAAKSSISEDLVIIKRIFDETGVGTIKTYAGVSGGVVFTPEISDEHSRKIVSEIATLMRESNRILPGGYIYLSDILGSPKNLDKIGKIIAHAYAGKQIDAVMTIATKGIPIAQAVSAILDVPFVIVRRDPKVTEGATLNVNYMSGSSSKVENMTLSKRSLAPGQRVLIVDDFMKGGGTLNGMKSLVHEFDCLLAGVAVFAEGPFKGQRLISDFKSILKIKSIDIEDRSIDVALGNIYDA
>NZ_LN774769.1|WP_047916390.1|2314247_2316323_-|elongation-factor-G
MAREFSLENTRNIGIMAHVDAGKTTTTERVLYYTGKIHKIGETHEGASQMDWMAQEQERGITITSAATTAAWHDTRINIIDTPGHVDFTIEVQRSLRVLDGAVTVLDAQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFFYSLNTLHDRLNANAHPIQIPIGAEEDFEGIIDLVRMRAEVYTNDLGTDILDEEIPEEYLAQAEEWRAKLIEAVADTDEDIMMKYLEGEEITEAELKAAIRKATINVEFYPMLAGSAFKNKGVQMMLDAVVDYLPAPTDVPAIKGVTPDGEETERHADDSEPFAALAFKVMTDPFVGRLTFFRVYSGVLSSGSYVLNASKGKRERIGRILQMHANTRNEINDVFSGDIAAAVGLKDTTTGDSLTDEKNPVILESIEFPEPVIQVMVEPKSKADQDKMGVALQKLAEEDPSFRVETNVETGETLIAGMGELHLDILVDRMRREFNVDANVGAPQVSYRETFRAPVTQAEGKFVRQSGGKGQYGHVWVEFTPNEEGKGFEFENAIVGGVVPREYIPAVEKGLAEAMQNGVLAGYPLVDVKAKLYDGSYHDVDSNETAFRVAASYALKAAAPKAKPVILEPMMKVTVTVPEENLGDIMGHVTARRGRVEGMEAHGNSQIVHAFVPLAEMFGYATTLRSSTQGRGTFMMVFDHYEDVPKSVQEAIIKKNQG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

540510 : 610066

Streptococcus_phage(30.0%)

transposase,integrase

attL 539810:539840|attR 542556:542586

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
539810:539840	attL	NA	NA	NA	NA
WP_047914552.1\|540510_541461_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047914975.1\|541475_542474_+\|integrase	site-specific integrase	A0A0C5AN64	Paenibacillus_phage	1.1e-17	27.1
WP_047914927.1\|542687_543623_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	7.7e-37	36.2
542556:542586	attR	NA	NA	NA	NA
WP_050702949.1\|543963_547695_+	VWA domain-containing protein	NA	NA	NA	NA
WP_047914976.1\|547742_549245_+	SpaH/EbpB family LPXTG-anchored major pilin	NA	NA	NA	NA
WP_047914977.1\|549342_550578_+	class C sortase	NA	NA	NA	NA
WP_047914978.1\|550580_551759_+	class C sortase	NA	NA	NA	NA
WP_047914979.1\|552055_552871_+	PRD domain-containing protein	NA	NA	NA	NA
WP_047914980.1\|552975_554913_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_047914981.1\|554923_556417_+	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_047914982.1\|556543_557653_+	SPASM domain-containing protein	NA	NA	NA	NA
WP_047914983.1\|557652_558429_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_047914984.1\|558494_559025_-	DUF1273 family protein	NA	NA	NA	NA
WP_047914985.1\|559337_559952_+	Holliday junction resolvase RecU	NA	NA	NA	NA
WP_050703073.1\|559965_561945_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_167594958.1\|562511_563459_+	FUSC family protein	NA	NA	NA	NA
WP_047914987.1\|563531_564539_+	alpha/beta hydrolase	A0A2L2DMU8	Acanthamoeba_polyphaga_mimivirus	3.8e-13	28.5
WP_050702952.1\|564684_565425_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_047914988.1\|565429_567934_+	bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	NA	NA	NA	NA
WP_047914989.1\|567938_568997_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_047914990.1\|569076_569634_+	elongation factor P	NA	NA	NA	NA
WP_047916503.1\|569678_570089_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_099046809.1\|570078_570693_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_047914991.1\|570939_571884_+	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_082095462.1\|572204_573665_+	glycoside hydrolase family 13 protein	NA	NA	NA	NA
WP_050702953.1\|573768_575022_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.2e-63	36.1
WP_082095463.1\|575417_577574_+	1,4-alpha-glucan branching protein GlgB	NA	NA	NA	NA
WP_047914994.1\|577679_578825_+	glucose-1-phosphate adenylyltransferase	NA	NA	NA	NA
WP_047914995.1\|578811_579960_+	glucose-1-phosphate adenylyltransferase subunit GlgD	NA	NA	NA	NA
WP_047914996.1\|579956_581396_+	glycogen synthase GlgA	NA	NA	NA	NA
WP_047914997.1\|581476_583870_+	glycogen/starch/alpha-glucan phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	5.4e-10	34.5
WP_047914998.1\|583943_584900_-	ABC transporter permease	NA	NA	NA	NA
WP_047914999.1\|584896_585994_-	ABC transporter permease	NA	NA	NA	NA
WP_047915000.1\|585993_587508_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-20	30.6
WP_047915001.1\|587829_588882_-	BMP family ABC transporter substrate-binding protein	A0A0A7DN02	Lactobacillus_phage	5.6e-52	39.1
WP_068876843.1\|589126_590059_-	membrane protein insertase YidC	NA	NA	NA	NA
WP_047915002.1\|590303_592007_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	9.6e-219	66.7
WP_047915003.1\|592092_592674_-	ECF transporter S component	NA	NA	NA	NA
WP_047915004.1\|592769_593309_-	phosphopantothenoylcysteine decarboxylase	Q9J5A8	Fowlpox_virus	4.5e-21	35.6
WP_047915005.1\|593277_593991_-	phosphopantothenate--cysteine ligase	NA	NA	NA	NA
WP_047915006.1\|594134_594320_-	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_047915007.1\|594679_595564_+	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_047915008.1\|595560_596208_+	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_050702954.1\|596267_597404_+	DNA repair exonuclease	NA	NA	NA	NA
WP_047915009.1\|597393_599559_+	AAA family ATPase	NA	NA	NA	NA
WP_047915010.1\|599555_600503_+	HD domain-containing protein	NA	NA	NA	NA
WP_047914556.1\|600645_601596_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047915011.1\|601689_602253_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_047915012.1\|602430_603303_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_047915013.1\|603477_604587_+	cystathionine gamma-synthase	NA	NA	NA	NA
WP_047915014.1\|604594_605758_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_047915015.1\|605857_606493_+	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_047915016.1\|606495_606816_+	hypothetical protein	NA	NA	NA	NA
WP_047916508.1\|606989_608825_+	APC family permease	NA	NA	NA	NA
WP_047915017.1\|608980_610066_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.5e-47	32.7

DBSCAN-SWA_2

615383 : 658021

Lactococcus_phage(42.86%)

tRNA,portal,terminase,transposase,protease,capsid,holin,integrase,tail,head

attL 616325:616353|attR 656726:656754

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047915023.1\|615383_616334_+\|transposase	IS30 family transposase	NA	NA	NA	NA
616325:616353	attL	NA	NA	NA	NA
WP_047915024.1\|616525_617821_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_047915025.1\|617903_618248_-	DUF1831 domain-containing protein	NA	NA	NA	NA
WP_047915026.1\|618307_619432_-	cysteine desulfurase	A0A1X7C038	Faustovirus	7.4e-34	28.1
WP_047915027.1\|619483_620449_-	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	2.5e-38	33.8
WP_047915028.1\|620746_621865_+	hypothetical protein	NA	NA	NA	NA
WP_047915029.1\|622101_622923_+	SseB family protein	NA	NA	NA	NA
WP_047915030.1\|622989_623583_+	serine acetyltransferase	NA	NA	NA	NA
WP_047915031.1\|623640_625011_+\|tRNA	cysteine--tRNA ligase	A0A161HRB7	Powai_lake_megavirus	3.5e-46	34.5
WP_047915032.1\|625003_625405_+	Mini-ribonuclease 3	NA	NA	NA	NA
WP_157761113.1\|625467_625560_+	DUF1033 family protein	NA	NA	NA	NA
WP_047915033.1\|625664_626573_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_050702955.1\|626776_627814_+	hypothetical protein	A0A2D1GPN7	Lactobacillus_phage	1.7e-16	44.7
WP_047915034.1\|627858_628116_+	hypothetical protein	NA	NA	NA	NA
WP_047915035.1\|629019_629199_+	hypothetical protein	NA	NA	NA	NA
WP_047914556.1\|630435_631386_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_157761114.1\|631575_631740_+	hypothetical protein	NA	NA	NA	NA
WP_047915037.1\|631827_632739_+	hypothetical protein	NA	NA	NA	NA
WP_047915038.1\|632835_634134_+	hypothetical protein	NA	NA	NA	NA
WP_047915039.1\|634514_634838_+	HNH endonuclease	A0A0S2SXR6	Bacillus_phage	1.7e-20	51.2
WP_047915040.1\|635022_635385_+\|terminase	P27 family phage terminase small subunit	Q9AZY9	Lactococcus_phage	2.1e-30	64.0
WP_047915041.1\|635388_637206_+\|terminase	terminase large subunit	Q9AZY8	Lactococcus_phage	9.1e-167	51.3
WP_047915042.1\|637226_638435_+\|portal	phage portal protein	Q9AZY7	Lactococcus_phage	4.1e-115	56.8
WP_047915043.1\|638435_639014_+\|head,protease	HK97 family phage prohead protease	Q9AZY6	Lactococcus_phage	6.4e-58	61.9
WP_047915044.1\|639004_640252_+\|capsid	phage major capsid protein	A0A0U4IB53	Exiguobacterium_phage	1.9e-59	43.6
WP_047915045.1\|640311_640587_+	hypothetical protein	Q9AZY3	Lactococcus_phage	2.1e-19	61.0
WP_047915046.1\|640586_640901_+\|head	phage head closure protein	Q9AZY2	Lactococcus_phage	3.8e-12	44.1
WP_047915047.1\|640901_641249_+	hypothetical protein	A0A0U4II15	Exiguobacterium_phage	4.9e-13	51.2
WP_050702956.1\|641245_641800_+	hypothetical protein	Q9AZY0	Lactococcus_phage	3.4e-16	42.9
WP_047915048.1\|641814_642402_+	hypothetical protein	A0A0U4JWV5	Exiguobacterium_phage	5.7e-38	47.9
WP_047915049.1\|642463_642823_+	hypothetical protein	A0A290GJX3	Caldibacillus_phage	1.2e-27	54.6
WP_047915050.1\|642828_643029_+	hypothetical protein	NA	NA	NA	NA
WP_050702957.1\|643145_646253_+\|tail	phage tail tape measure protein	E3W8G4	Leuconostoc_phage	5.1e-69	35.4
WP_047915051.1\|646257_646947_+	hypothetical protein	A0A1C8EA72	Bacillus_phage	3.2e-24	31.8
WP_157761151.1\|647924_651023_+	hypothetical protein	NA	NA	NA	NA
WP_047915052.1\|651024_651258_+	hypothetical protein	Q9AZX0	Lactococcus_phage	1.0e-14	57.7
WP_047915053.1\|651277_651676_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	8.6e-30	49.2
WP_047915054.1\|651739_652948_-	FRG domain-containing protein	Q9AZ51	Lactococcus_phage	1.0e-17	44.2
WP_047915055.1\|653326_653689_+	DUF1033 family protein	NA	NA	NA	NA
WP_047915056.1\|653835_654096_-	hypothetical protein	NA	NA	NA	NA
WP_047915057.1\|654116_654425_-	hypothetical protein	NA	NA	NA	NA
WP_050703076.1\|654426_655575_-	hypothetical protein	NA	NA	NA	NA
WP_047914552.1\|655784_656735_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_157761115.1\|656849_657026_-	hypothetical protein	NA	NA	NA	NA
656726:656754	attR	NA	NA	NA	NA
WP_047914556.1\|657070_658021_-\|transposase	IS30 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

747343 : 767960

Bacillus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047914552.1\|747343_748294_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_050702963.1\|748378_748918_+	EAL domain-containing protein	NA	NA	NA	NA
WP_047915124.1\|748952_750008_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_047915125.1\|750080_752057_+	glycosyltransferase	NA	NA	NA	NA
WP_050702964.1\|752353_753223_+	hypothetical protein	NA	NA	NA	NA
WP_047914552.1\|753182_754133_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_050702965.1\|754239_754656_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_047915126.1\|754645_755503_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_047915127.1\|755797_756067_+	30S ribosomal protein S14	NA	NA	NA	NA
WP_167594967.1\|756094_756166_+	putative metal homeostasis protein	NA	NA	NA	NA
WP_047915128.1\|756167_756704_+	NUDIX hydrolase	NA	NA	NA	NA
WP_047915129.1\|756807_757338_+	hypothetical protein	NA	NA	NA	NA
WP_050702966.1\|758045_758576_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_047915130.1\|758979_759279_-	DUF2087 domain-containing protein	NA	NA	NA	NA
WP_047915131.1\|759281_760505_-	MFS transporter	NA	NA	NA	NA
WP_047914552.1\|760830_761781_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047915132.1\|762603_763152_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_047915133.1\|764051_764288_+	DUF86 domain-containing protein	NA	NA	NA	NA
WP_047914552.1\|764320_765271_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047915134.1\|765635_766760_+	cation:proton antiporter	NA	NA	NA	NA
WP_082095397.1\|767121_767379_-\|transposase	transposase	A0A1P8CWQ3	Bacillus_phage	9.8e-19	56.4
WP_050702967.1\|767375_767960_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	4.8e-29	42.9

DBSCAN-SWA_4

782046 : 809608

Lactococcus_phage(20.0%)

integrase

attL 792020:792042|attR 810431:810453

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047915147.1\|782046_782664_+	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	4.9e-24	37.1
WP_047915148.1\|782653_783907_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	1.3e-103	55.3
WP_047915149.1\|783909_784893_+	nucleoid-associated protein	NA	NA	NA	NA
WP_047915150.1\|784943_785537_+	Pneumococcal vaccine antigen A	A0A1W6JSC2	Bacillus_phage	7.1e-20	38.5
WP_047915151.1\|785633_787244_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	4.6e-21	30.1
WP_047915152.1\|787313_788183_+	5,10-methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_047915153.1\|788267_788543_-	acylphosphatase	NA	NA	NA	NA
WP_047916525.1\|788709_789495_+	NUDIX hydrolase	G3MA14	Bacillus_virus	1.4e-26	33.2
WP_047915154.1\|789609_790386_+	nicotinamide mononucleotide transporter	Q5ULN1	Lactobacillus_virus	3.5e-51	40.9
WP_047916526.1\|790527_791256_+	RNA methyltransferase	NA	NA	NA	NA
WP_047915155.1\|791425_792037_+	30S ribosomal protein S4	NA	NA	NA	NA
792020:792042	attL	NA	NA	NA	NA
WP_047915156.1\|792129_793263_-\|integrase	site-specific integrase	C9E2L6	Enterococcus_phage	1.6e-57	36.7
WP_047915157.1\|793382_794012_-	hypothetical protein	NA	NA	NA	NA
WP_050702969.1\|794096_794861_-	helix-turn-helix transcriptional regulator	A0A1S5SD15	Streptococcus_phage	6.5e-66	52.0
WP_047915159.1\|795086_795836_-	hypothetical protein	NA	NA	NA	NA
WP_047915160.1\|796001_796241_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047915161.1\|796252_797032_+	prophage antirepressor	Q38330	Lactococcus_phage	3.4e-78	60.0
WP_157761117.1\|797043_797256_+	hypothetical protein	NA	NA	NA	NA
WP_047915162.1\|797197_797539_-	hypothetical protein	NA	NA	NA	NA
WP_047915163.1\|797656_797845_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047915164.1\|797922_798228_+	hypothetical protein	NA	NA	NA	NA
WP_157761118.1\|798327_798498_+	hypothetical protein	NA	NA	NA	NA
WP_047915165.1\|798507_799086_+	hypothetical protein	NA	NA	NA	NA
WP_047915166.1\|799078_799336_+	hypothetical protein	NA	NA	NA	NA
WP_047915167.1\|799337_799739_+	hypothetical protein	A0A1X9IGE4	Lactococcus_phage	2.8e-36	57.1
WP_047916527.1\|799747_799936_+	hypothetical protein	J9QD21	Clostridium_phage	2.0e-13	69.8
WP_047915168.1\|799980_802248_+	hypothetical protein	D2XR26	Bacillus_phage	6.5e-13	39.6
WP_050702970.1\|802244_802961_+	hypothetical protein	B3GW14	Streptococcus_phage	5.7e-32	36.1
WP_050702971.1\|802957_806440_+	hypothetical protein	B3GW15	Streptococcus_phage	8.3e-52	31.5
WP_047915169.1\|806426_806840_+	DUF1617 family protein	Q9AZX1	Lactococcus_phage	4.9e-20	62.2
WP_047915170.1\|806841_807072_+	hypothetical protein	Q6SE67	Lactobacillus_prophage	1.1e-08	40.3
WP_047915171.1\|807081_807411_+	hypothetical protein	A0A1X9IGI3	Lactococcus_phage	6.0e-37	71.7
WP_047915172.1\|807407_807617_+	hypothetical protein	E7DNC2	Pneumococcus_phage	9.5e-12	59.7
WP_047915173.1\|807609_807801_+	hypothetical protein	NA	NA	NA	NA
WP_047915174.1\|807790_808636_+	peptidoglycan hydrolase	O64298	Streptococcus_virus	3.0e-48	44.4
WP_167594959.1\|808832_809000_+	hypothetical protein	NA	NA	NA	NA
WP_099046834.1\|809008_809608_+	GNAT family N-acetyltransferase	A0A0A8WFI2	Clostridium_phage	1.8e-15	34.8
810431:810453	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1273553 : 1280808

Enterococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047915562.1\|1273553_1275371_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1H1Z3	Paramecium_bursaria_Chlorella_virus	3.5e-94	37.6
WP_047915563.1\|1275505_1276198_-	helix-turn-helix domain-containing protein	A0A1S5SD15	Streptococcus_phage	3.1e-59	47.9
WP_047915564.1\|1276296_1276938_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_047915565.1\|1277042_1277261_+	glutaredoxin-like protein NrdH	A0A1W6JHV4	Lactococcus_phage	1.7e-11	47.6
WP_047915566.1\|1277257_1277614_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	D9J0S1	Brochothrix_phage	1.6e-14	32.8
WP_047915567.1\|1277618_1279772_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	4.2e-256	61.1
WP_047915568.1\|1279845_1280808_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	7.0e-126	68.2

DBSCAN-SWA_6

1532929 : 1586476

Bacillus_phage(14.29%)

transposase,tRNA,integrase

attL 1577523:1577547|attR 1586486:1586510

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047915756.1\|1532929_1534198_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	3.9e-92	47.4
WP_050703013.1\|1534197_1534926_+	hypothetical protein	NA	NA	NA	NA
WP_050703014.1\|1534964_1535471_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_047915757.1\|1535606_1536542_-	ABC transporter permease	NA	NA	NA	NA
WP_047915758.1\|1536534_1537230_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	7.5e-29	35.3
WP_050703015.1\|1537302_1538403_-	peptide chain release factor 2	NA	NA	NA	NA
WP_047915759.1\|1538404_1539481_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_099046808.1\|1539700_1541093_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.0e-57	44.9
WP_047915760.1\|1541192_1541567_-	PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM	NA	NA	NA	NA
WP_047916607.1\|1541568_1542150_-	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
WP_047915761.1\|1542166_1543156_-	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_047915762.1\|1543337_1543889_+	dihydroxyacetone kinase transcriptional activator DhaS	NA	NA	NA	NA
WP_047915763.1\|1543943_1544921_-	DhaKLM operon coactivator DhaQ	NA	NA	NA	NA
WP_050703016.1\|1545251_1545677_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_047914552.1\|1545673_1546624_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047915764.1\|1546763_1547903_+	MFS transporter	NA	NA	NA	NA
WP_047915765.1\|1547974_1548841_+	phosphoesterase	NA	NA	NA	NA
WP_047915766.1\|1548912_1549440_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_047915767.1\|1549531_1550413_-	ROK family protein	NA	NA	NA	NA
WP_047915768.1\|1550716_1552660_-	PTS beta-glucoside transporter subunit IIBCA	NA	NA	NA	NA
WP_082095428.1\|1552754_1554341_+	sucrose-6-phosphate hydrolase	F8WPR5	Bacillus_phage	5.2e-17	25.2
WP_047915769.1\|1554457_1555210_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_047915770.1\|1555327_1556998_-	alpha-glucosidase	NA	NA	NA	NA
WP_047915771.1\|1557080_1557911_-	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_047915772.1\|1557924_1558755_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_082095429.1\|1558770_1559718_-	PTS mannose/fructose/sorbose transporter subunit IIAB	NA	NA	NA	NA
WP_047915773.1\|1560147_1561104_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_099046816.1\|1561257_1561869_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_047915775.1\|1562008_1563301_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.4e-17	26.7
WP_047916611.1\|1563448_1564498_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_047915776.1\|1564511_1565006_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	7.0e-21	42.7
WP_047915777.1\|1564998_1566252_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_082095430.1\|1566492_1567236_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_047914552.1\|1567279_1568230_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_157761132.1\|1568189_1568450_-	hypothetical protein	NA	NA	NA	NA
WP_047915778.1\|1568513_1568906_-	cytidine deaminase	NA	NA	NA	NA
WP_047915779.1\|1568889_1569555_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_047915780.1\|1569551_1570841_-	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	3.1e-105	51.0
WP_047915781.1\|1571091_1571652_-	signal peptidase I	NA	NA	NA	NA
WP_047915782.1\|1571785_1571992_-	DUF2969 family protein	NA	NA	NA	NA
WP_047915783.1\|1572088_1572406_-	thioredoxin	A0A1J0GW78	Streptomyces_phage	5.6e-16	45.1
WP_047915784.1\|1572797_1574357_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	6.4e-44	28.4
WP_047915785.1\|1574509_1576846_-	endonuclease MutS2	Q94M10	Lactobacillus_phage	2.0e-17	58.1
WP_047916613.1\|1576852_1577413_-	colicin V production protein	NA	NA	NA	NA
1577523:1577547	attL	NA	NA	NA	NA
WP_047914552.1\|1578228_1579179_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047915787.1\|1579234_1579687_-	hypothetical protein	NA	NA	NA	NA
WP_157761133.1\|1580447_1580594_-	hypothetical protein	Q9AZG6	Lactococcus_phage	3.9e-12	83.0
WP_050703017.1\|1580603_1581128_-	hypothetical protein	NA	NA	NA	NA
WP_047915788.1\|1581431_1582052_-	antirepressor	A0A1W6JPC3	Staphylococcus_phage	2.0e-41	45.0
WP_047914552.1\|1582118_1583069_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_050703018.1\|1583493_1583982_+	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	7.4e-07	44.4
WP_047915790.1\|1584053_1584416_+	hypothetical protein	NA	NA	NA	NA
WP_047915791.1\|1584727_1584940_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_047915792.1\|1585285_1586476_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	2.3e-86	45.1
1586486:1586510	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1639856 : 1650756

Planktothrix_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047915838.1\|1639856_1640732_-	phosphate ABC transporter substrate-binding protein	E3SLK5	Synechococcus_phage	8.6e-06	28.9
WP_047915839.1\|1640960_1641980_-	NAD(P)/FAD-dependent oxidoreductase	A0A1V0SIN1	Klosneuvirus	2.1e-11	24.8
WP_047915840.1\|1642008_1643046_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_047915841.1\|1643104_1643866_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.9e-11	27.5
WP_047915842.1\|1643868_1644936_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	3.1e-18	26.4
WP_047915843.1\|1645134_1645605_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	8.9e-42	54.5
WP_047915844.1\|1645707_1648005_-	ribonuclease R	Q0GXV6	Lactococcus_phage	2.1e-91	40.2
WP_079506756.1\|1648221_1648470_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_047915845.1\|1648685_1649609_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.1e-83	49.4
WP_047915846.1\|1649770_1649995_-	DUF4059 family protein	NA	NA	NA	NA
WP_047915847.1\|1649994_1650756_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-29	38.7

DBSCAN-SWA_8

1834933 : 1886375

Klosneuvirus(28.57%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047914556.1\|1834933_1835884_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047915975.1\|1836049_1839463_-	pyruvate carboxylase	NA	NA	NA	NA
WP_047915976.1\|1839610_1840870_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_082095437.1\|1841195_1841342_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_047916636.1\|1841331_1842537_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_047915977.1\|1842711_1843290_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_047915978.1\|1843379_1843685_+	DUF1827 family protein	NA	NA	NA	NA
WP_047915979.1\|1843880_1846181_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.9e-113	32.5
WP_047915980.1\|1846380_1847295_-	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_047915981.1\|1847451_1848414_+	asparaginase	NA	NA	NA	NA
WP_047915982.1\|1848569_1849895_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	6.8e-196	80.3
WP_047915983.1\|1850105_1850657_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_047915984.1\|1850738_1853180_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A0A8J958	Klebsiella_phage	7.5e-124	37.4
WP_047915985.1\|1853256_1853697_-	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_047915986.1\|1854021_1854504_-	transcription elongation factor GreA	NA	NA	NA	NA
WP_047915987.1\|1854623_1856189_-	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_047915988.1\|1856340_1856895_-	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_047915989.1\|1857000_1857513_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.0e-30	44.3
WP_047915990.1\|1857514_1859740_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.1e-76	31.8
WP_050703029.1\|1859736_1860471_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_047915991.1\|1860471_1861407_-	ribonuclease Z	NA	NA	NA	NA
WP_047915992.1\|1861732_1862626_-	SPFH domain-containing protein	A0A1V0SL90	Klosneuvirus	8.1e-36	36.4
WP_047915993.1\|1862633_1863296_-	hypothetical protein	NA	NA	NA	NA
WP_047915994.1\|1863297_1864536_-	GTPase HflX	NA	NA	NA	NA
WP_047916638.1\|1864522_1865413_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_047914556.1\|1865479_1866430_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047915995.1\|1867079_1867883_-	serine/threonine protein phosphatase	NA	NA	NA	NA
WP_047915996.1\|1867884_1868667_-	phosphate/phosphonate ABC transporter permease	NA	NA	NA	NA
WP_082095438.1\|1868666_1869359_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_047915998.1\|1870313_1870982_+	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_047914552.1\|1871196_1872147_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047915999.1\|1873019_1873547_-	YqeG family HAD IIIA-type phosphatase	NA	NA	NA	NA
WP_047916000.1\|1873762_1875424_-	iron ABC transporter permease	NA	NA	NA	NA
WP_047916001.1\|1875427_1876513_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-25	35.3
WP_047916002.1\|1876603_1877668_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_047916003.1\|1877836_1878619_-	response regulator	NA	NA	NA	NA
WP_157761138.1\|1878611_1880315_-	histidine kinase	NA	NA	NA	NA
WP_047914552.1\|1880429_1881380_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_050703030.1\|1881474_1883175_-	hypothetical protein	NA	NA	NA	NA
WP_047916005.1\|1883613_1884585_+	N(5)-(carboxyethyl)ornithine synthase	NA	NA	NA	NA
WP_047916006.1\|1885047_1885383_-	cupin domain-containing protein	NA	NA	NA	NA
WP_047914556.1\|1885424_1886375_-\|transposase	IS30 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

2030951 : 2074754

Lactococcus_phage(37.84%)

portal,terminase,transposase,capsid,integrase,holin,tail

attL 2035694:2035715|attR 2072220:2072241

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047916655.1\|2030951_2032055_-	LysM peptidoglycan-binding domain-containing protein	A5GYL4	Lactococcus_phage	1.3e-120	59.8
WP_050703038.1\|2032752_2033490_-	CHAP domain-containing protein	R9R2F8	Lactococcus_phage	1.3e-10	38.0
WP_047916131.1\|2033655_2034057_-	hypothetical protein	NA	NA	NA	NA
WP_047916132.1\|2034462_2034807_+	helix-turn-helix domain-containing protein	A0A1X9IGD3	Lactococcus_phage	1.3e-42	73.7
WP_047916133.1\|2034821_2035409_+	hypothetical protein	Q9AZF6	Lactococcus_phage	4.2e-57	54.1
2035694:2035715	attL	NA	NA	NA	NA
WP_050703039.1\|2035824_2036205_-	hypothetical protein	NA	NA	NA	NA
WP_047916134.1\|2036207_2036660_-	SocA family protein	A0A0N9SGM1	Paenibacillus_phage	3.2e-20	39.3
WP_047916135.1\|2036842_2037691_-	peptidoglycan hydrolase	B3GW20	Streptococcus_phage	4.2e-50	43.6
WP_047916136.1\|2037680_2037869_-	hypothetical protein	NA	NA	NA	NA
WP_047916137.1\|2037861_2038080_-	hypothetical protein	A0A1U9WRD5	Streptococcus_virus	1.6e-09	48.6
WP_047916138.1\|2038084_2038327_-\|holin	holin	D2J075	Enterococcus_phage	6.0e-10	50.0
WP_047916140.1\|2038531_2042146_-	hypothetical protein	M1IFB6	Streptococcus_phage	1.6e-58	31.5
WP_047916141.1\|2042145_2043708_-	hypothetical protein	A0A1P8VVL3	Streptococcus_phage	1.1e-48	30.3
WP_047916142.1\|2043708_2046183_-	hypothetical protein	NA	NA	NA	NA
WP_047916143.1\|2046412_2047018_-	hypothetical protein	NA	NA	NA	NA
WP_050703040.1\|2047017_2047269_-	hypothetical protein	NA	NA	NA	NA
WP_047916145.1\|2047376_2047757_-	hypothetical protein	A0A1L2JXK6	Streptococcus_phage	1.9e-10	38.1
WP_047916146.1\|2047817_2048321_-\|tail	phage major tail protein, TP901-1 family	A0A0S2MYF4	Enterococcus_phage	9.6e-34	45.1
WP_047916147.1\|2048329_2048719_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_047916148.1\|2048731_2049097_-	hypothetical protein	NA	NA	NA	NA
WP_047916149.1\|2049089_2049392_-	hypothetical protein	NA	NA	NA	NA
WP_047916150.1\|2049388_2049721_-	hypothetical protein	Q8LTQ7	Lactococcus_phage	2.2e-10	40.2
WP_157761141.1\|2049744_2049888_-	hypothetical protein	NA	NA	NA	NA
WP_047916151.1\|2049901_2050738_-\|capsid	N4-gp56 family major capsid protein	A0A141E1A1	Streptococcus_phage	2.7e-65	51.3
WP_047916152.1\|2050753_2051353_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_047916153.1\|2051456_2052365_-\|capsid	minor capsid protein	A0A2P1JTW9	Anoxybacillus_phage	8.0e-55	40.5
WP_047916154.1\|2052368_2053685_-\|portal	phage portal protein	A0A1P8BLJ1	Lactococcus_phage	6.3e-101	48.4
WP_047916155.1\|2053684_2054962_-\|terminase	PBSX family phage terminase large subunit	D7RWC5	Brochothrix_phage	4.0e-193	74.8
WP_047916156.1\|2054958_2055381_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.2e-21	46.5
WP_047916157.1\|2055925_2056330_-	hypothetical protein	NA	NA	NA	NA
WP_047916158.1\|2056385_2056661_-	hypothetical protein	NA	NA	NA	NA
WP_047916159.1\|2056757_2056949_-	hypothetical protein	NA	NA	NA	NA
WP_050703041.1\|2056945_2057500_-	DUF1642 domain-containing protein	A5GYN8	Lactococcus_phage	2.9e-07	30.9
WP_047916160.1\|2057496_2057787_-	hypothetical protein	Q9AZU4	Lactococcus_phage	2.8e-06	43.6
WP_047916161.1\|2057783_2058002_-	hypothetical protein	NA	NA	NA	NA
WP_068876856.1\|2057994_2058507_-	DUF3310 domain-containing protein	E5DV94	Deep-sea_thermophilic_phage	1.8e-16	62.5
WP_157761142.1\|2058496_2058634_-	hypothetical protein	NA	NA	NA	NA
WP_047916162.1\|2058630_2059023_-	hypothetical protein	Q9XJF2	Lactococcus_phage	2.0e-42	72.3
WP_047916163.1\|2059019_2059283_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047916660.1\|2059294_2060116_-	site-specific DNA-methyltransferase	X2KR14	Campylobacter_phage	2.8e-91	65.3
WP_047916164.1\|2060151_2060544_-	RusA family crossover junction endodeoxyribonuclease	Q9MC30	Lactococcus_phage	8.2e-41	66.2
WP_047916165.1\|2060540_2060729_-	hypothetical protein	NA	NA	NA	NA
WP_047916166.1\|2060737_2061616_-	ATP-binding protein	R9QM21	Lactococcus_phage	1.2e-76	52.3
WP_047916167.1\|2061627_2062395_-	DNA replication protein	A0A1X9IGE9	Lactococcus_phage	1.2e-91	75.7
WP_157761143.1\|2062395_2062551_-	hypothetical protein	NA	NA	NA	NA
WP_047916169.1\|2062769_2063210_-	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	9.2e-49	68.5
WP_047916170.1\|2063206_2063827_-	ERF family protein	A0A1P8BKZ7	Lactococcus_phage	4.9e-40	66.4
WP_047916171.1\|2063828_2064239_-	hypothetical protein	NA	NA	NA	NA
WP_047916172.1\|2064242_2064503_-	hypothetical protein	NA	NA	NA	NA
WP_047916173.1\|2064751_2065030_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_050703042.1\|2065102_2065291_-	helix-turn-helix domain-containing protein	B3GVX6	Streptococcus_phage	3.3e-08	51.6
WP_047916174.1\|2065407_2065599_+	hypothetical protein	NA	NA	NA	NA
WP_047916175.1\|2065575_2065809_-	hypothetical protein	NA	NA	NA	NA
WP_047916176.1\|2065866_2066052_-	hypothetical protein	NA	NA	NA	NA
WP_050703043.1\|2066044_2066578_-	hypothetical protein	A0A286QNA7	Streptococcus_phage	1.1e-14	42.0
WP_157761144.1\|2066574_2067393_-	hypothetical protein	J7KDG2	Streptococcus_phage	3.3e-15	29.5
WP_047916178.1\|2067466_2067766_-	DUF559 domain-containing protein	NA	NA	NA	NA
WP_047916179.1\|2067984_2068239_-	DUF739 family protein	O34036	Streptococcus_phage	3.5e-08	43.2
WP_047916180.1\|2068419_2069142_+	helix-turn-helix transcriptional regulator	A0A1S5SD15	Streptococcus_phage	2.7e-61	51.9
WP_099046825.1\|2069201_2069375_+	hypothetical protein	A0A097BY73	Enterococcus_phage	4.9e-14	75.0
WP_047914552.1\|2069469_2070420_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_047916182.1\|2071121_2072204_+\|integrase	site-specific integrase	A0A172LN96	Lactococcus_phage	6.7e-125	60.6
WP_047916183.1\|2072766_2073390_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	6.7e-53	51.5
2072220:2072241	attR	NA	NA	NA	NA
WP_047916184.1\|2073479_2074754_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	5.3e-121	53.6

DBSCAN-SWA_10

2191960 : 2251693

Lactococcus_phage(20.0%)

tRNA,portal,terminase,protease,capsid,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047916287.1\|2191960_2192950_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_047916288.1\|2193080_2193932_-	YitT family protein	M1Q1P6	Streptococcus_phage	1.2e-47	39.0
WP_050703051.1\|2194010_2194886_-	YitT family protein	NA	NA	NA	NA
WP_047916290.1\|2194888_2196631_-\|tRNA	aspartate--tRNA ligase	A0A2K9L424	Tupanvirus	4.7e-19	27.4
WP_047916291.1\|2196686_2196917_-	hypothetical protein	NA	NA	NA	NA
WP_047916292.1\|2196909_2198199_-\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_047916293.1\|2198440_2198986_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_050703052.1\|2198993_2199863_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_047916674.1\|2199947_2201234_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	2.8e-05	25.1
WP_047916294.1\|2201223_2202486_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.5e-80	39.6
WP_047916295.1\|2202699_2203098_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	6.2e-12	48.6
WP_047916296.1\|2203104_2204181_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_047916297.1\|2204229_2205168_-	carbamate kinase	NA	NA	NA	NA
WP_047916298.1\|2205177_2206275_-	agmatine deiminase	M1HPC5	Acanthocystis_turfacea_Chlorella_virus	1.1e-95	48.2
WP_047916299.1\|2206298_2207666_-	amino acid permease	NA	NA	NA	NA
WP_047916300.1\|2207750_2208773_-	putrescine carbamoyltransferase	A0A1J0F9B8	Only_Syngen_Nebraska_virus	5.7e-17	27.9
WP_047916301.1\|2209027_2210044_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_047916302.1\|2210130_2212482_-	penicillin-binding protein	NA	NA	NA	NA
WP_047916303.1\|2212649_2213903_+\|tRNA	tyrosine--tRNA ligase	A0A2C9CYK4	Yersinia_phage	1.4e-78	43.2
WP_047916304.1\|2214017_2215436_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	6.2e-22	26.1
WP_047916305.1\|2215452_2216676_-\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_047916306.1\|2216719_2217862_-	cysteine desulfurase	NA	NA	NA	NA
WP_047916307.1\|2218145_2218349_-	hypothetical protein	NA	NA	NA	NA
WP_047916308.1\|2218444_2218777_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047916309.1\|2218883_2219606_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_047916310.1\|2219685_2221731_-	sodium:proton antiporter	NA	NA	NA	NA
WP_047916311.1\|2221827_2222115_-	hypothetical protein	NA	NA	NA	NA
WP_047916312.1\|2222377_2222812_+	universal stress protein	NA	NA	NA	NA
WP_047916313.1\|2222849_2224076_-	peptidase T	NA	NA	NA	NA
WP_047916314.1\|2224200_2224491_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_047916315.1\|2224527_2224860_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_047916316.1\|2224875_2225187_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_047916317.1\|2225316_2227851_-	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	4.5e-63	25.8
WP_047916318.1\|2228035_2229328_-	adenylosuccinate synthase	G5CQQ4	Megavirus	6.6e-71	37.2
WP_047916319.1\|2229755_2230079_-	glutaredoxin family protein	NA	NA	NA	NA
WP_167594965.1\|2230094_2230265_-	hypothetical protein	A0A182BQ76	Lactococcus_phage	9.1e-05	61.1
WP_047916320.1\|2230374_2231703_-	LysM peptidoglycan-binding domain-containing protein	A0A1P8BMS7	Lactococcus_phage	4.9e-154	62.4
WP_047916321.1\|2231699_2232101_-\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	3.8e-41	63.8
WP_047916322.1\|2232103_2232340_-	hypothetical protein	Q9AZX0	Lactococcus_phage	2.1e-15	56.2
WP_050703053.1\|2232341_2232755_-	DUF1617 family protein	Q9AZX1	Lactococcus_phage	3.4e-21	65.9
WP_047916323.1\|2232741_2236362_-	hypothetical protein	B3GW15	Streptococcus_phage	3.2e-70	36.1
WP_047916324.1\|2236358_2237072_-	hypothetical protein	NA	NA	NA	NA
WP_050703054.1\|2237064_2241201_-	hypothetical protein	A0A1D3SNL5	Enterococcus_phage	5.6e-55	33.4
WP_050703055.1\|2241200_2241476_-	hypothetical protein	NA	NA	NA	NA
WP_047916327.1\|2241514_2241853_-	hypothetical protein	NA	NA	NA	NA
WP_047916328.1\|2241859_2242414_-	hypothetical protein	NA	NA	NA	NA
WP_047916329.1\|2242414_2242786_-	hypothetical protein	NA	NA	NA	NA
WP_050703056.1\|2242785_2243196_-	hypothetical protein	A0A0S2MVE4	Bacillus_phage	1.3e-12	37.0
WP_157761146.1\|2243188_2243518_-	hypothetical protein	NA	NA	NA	NA
WP_047916331.1\|2243498_2243828_-	hypothetical protein	NA	NA	NA	NA
WP_047916332.1\|2243836_2244160_-	hypothetical protein	NA	NA	NA	NA
WP_047916333.1\|2244177_2245077_-	hypothetical protein	U3PDP8	Lactobacillus_phage	6.0e-71	50.0
WP_050703057.1\|2245080_2245653_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_047916334.1\|2245762_2246584_-\|capsid	minor capsid protein	A0A2H4J4W7	uncultured_Caudovirales_phage	1.0e-21	29.3
WP_047916335.1\|2246516_2247911_-\|portal	phage portal protein	A0A0M4S669	Bacillus_phage	6.9e-82	42.9
WP_047916336.1\|2247919_2249206_-\|terminase	PBSX family phage terminase large subunit	D7RWC5	Brochothrix_phage	9.5e-203	81.6
WP_047916337.1\|2249198_2249648_-\|terminase	terminase small subunit	D7RWC4	Brochothrix_phage	5.9e-27	51.3
WP_050703058.1\|2249788_2250223_-	hypothetical protein	NA	NA	NA	NA
WP_047916338.1\|2250383_2250860_-	hypothetical protein	NA	NA	NA	NA
WP_047916339.1\|2250871_2251084_-	hypothetical protein	NA	NA	NA	NA
WP_047916340.1\|2251330_2251693_-	DUF1064 domain-containing protein	A0A1P8BMB7	Lactococcus_phage	7.1e-39	67.5

DBSCAN-SWA_11

2256896 : 2276000

Lactococcus_phage(28.57%)

tRNA,integrase

attL 2264574:2264590|attR 2273282:2273298

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047916679.1\|2256896_2258492_-	DEAD/DEAH box helicase	Q5YA94	Bacillus_phage	3.0e-206	67.0
WP_047916345.1\|2258499_2258730_-	hypothetical protein	NA	NA	NA	NA
WP_047916346.1\|2258732_2259344_-	hypothetical protein	A0A2I7SC41	Paenibacillus_phage	8.9e-18	39.1
WP_047916347.1\|2259362_2260466_-	AAA family ATPase	A0A0K2CZH1	Paenibacillus_phage	2.2e-91	50.3
WP_047916348.1\|2260462_2260756_-	hypothetical protein	NA	NA	NA	NA
WP_047916349.1\|2260752_2262042_-	AAA family ATPase	Q5YA97	Bacillus_phage	1.3e-143	62.5
WP_047916350.1\|2262066_2262372_-	hypothetical protein	NA	NA	NA	NA
WP_047916351.1\|2262631_2262937_-	hypothetical protein	NA	NA	NA	NA
WP_047916352.1\|2263020_2263227_-	hypothetical protein	NA	NA	NA	NA
WP_047916353.1\|2263512_2263905_+	helix-turn-helix domain-containing protein	A0A182BQC8	Lactococcus_phage	2.0e-31	55.4
WP_047916354.1\|2263918_2264506_+	hypothetical protein	Q9AZW4	Lactococcus_phage	1.4e-55	53.4
WP_047916355.1\|2264515_2264917_+	hypothetical protein	NA	NA	NA	NA
2264574:2264590	attL	NA	NA	NA	NA
WP_047916356.1\|2264965_2265625_+	hypothetical protein	A0A097BY93	Leuconostoc_phage	1.1e-08	59.6
WP_047916357.1\|2265744_2266890_+\|integrase	site-specific integrase	A0A1B1IMP1	Lactococcus_phage	1.5e-95	48.9
WP_047916358.1\|2266978_2268610_-	chaperonin GroEL	A0A240F779	uncultured_virus	6.5e-156	54.9
WP_047916359.1\|2268654_2268939_-	co-chaperone GroES	A0A221S4B1	uncultured_virus	8.9e-05	35.9
WP_047916360.1\|2269109_2270381_-	CHAP domain-containing protein	A0A2H4J2Z6	uncultured_Caudovirales_phage	3.0e-07	32.6
WP_047916361.1\|2270445_2270841_-	single-stranded DNA-binding protein	Q9AZV6	Lactococcus_phage	1.3e-22	41.8
WP_047916362.1\|2270897_2271521_-\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_047916363.1\|2271517_2271838_-	thioredoxin family protein	A0A0K2FIM3	Achromobacter_phage	2.0e-05	32.9
WP_047916364.1\|2271824_2272139_-	hypothetical protein	NA	NA	NA	NA
WP_047916365.1\|2272272_2273358_+	glutamyl aminopeptidase	NA	NA	NA	NA
2273282:2273298	attR	NA	NA	NA	NA
WP_157761149.1\|2273495_2276000_-	hypothetical protein	Q332B8	Clostridium_botulinum_C_phage	3.3e-10	30.8

Anti-CRISPR protein detection

Acr_ID: NZ_LN774769.1|WP_099046834.1|809008_809608_+|GNAT-family-N-acetyltransferase

Click the colored protein region to show detailed information

Acr_ID: NZ_LN774769.1|WP_047915350.1|999677_999986_+|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LN774769.1|WP_099046834.1|809008_809608_+|GNAT-family-N-acetyltransferase

809008_809608_+

199 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|89	0.4512820512820513	0.9798994974874372	0.9740932642487047

782046-809608

NZ_LN774769.1|WP_047915350.1|999677_999986_+|hypothetical-protein

999677_999986_+

102 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|58	0.4444444444444444	0.9803921568627451	0.97

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LN774770

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_LN774771

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_LN774769

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information