CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP011308	Sulfurovum lithotrophicum strain ATCC BAA-797 chromosome, complete genome	5 crisprs	DEDDh,cas3,WYL,cas9,cas1,cas2,csa3	0	12	3	0

1. NZ_CP011308

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011308_1

• CRISPR_ID: NZ_CP011308_1
• CRISPR_location: 132944-133066
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP011308_1

Consensus_repeat	Method
CGTTAAGAAAACGTGAACTGCTTCACGTTTTTAGCGTCG	CRISPRCasFinder

spacers of NZ_CP011308_1

>1.1|132983|45|NZ_CP011308|CRISPRCasFinder
AAACCGAAGCGGTGGAGCAAAGCGACCCGCGTAGGCTGGAAGAAC

CRISPR arrays and Neighbor proteins around NZ_CP011308_1

CRISPR arrays

The CRISPR arrays of NZ_CP011308_1

>merge|NZ_CP011308|1|132944-133066|CRISPRCasFinder
CGTTAAGAAAACGTGAACTGCTTCACGTTTTTAGCGTCGAAACCGAAGCGGTGGAGCAAAGCGACCCGCGTAGGCTGGAAGAACCGTTAAGAAAACGTGAACTGTTTCACGTTTTTAGCGTCG

>NZ_CP011308|1|1|132944-133066|CRISPRCasFinder
CGTTAAGAAAACGTGAACTGCTTCACGTTTTTAGCGTCG	AAACCGAAGCGGTGGAGCAAAGCGACCCGCGTAGGCTGGAAGAAC
CGTTAAGAAAACGTGAACTGTTTCACGTTTTTAGCGTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011308.1|WP_046550199.1|143700_144423_+|energy-transducer-TonB	unknown	unknown	gnl|CDD|223880
NZ_CP011308.1|WP_052746034.1|138095_142064_-|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319775
NZ_CP011308.1|WP_046550192.1|130202_131687_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl|CDD|235463
NZ_CP011308.1|WP_046550188.1|124427_125750_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl|CDD|223694
NZ_CP011308.1|WP_046550187.1|123293_124280_-|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl|CDD|366502
NZ_CP011308.1|WP_084721985.1|133940_134591_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP011308.1|WP_046550194.1|132195_132939_+|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl|CDD|235546
NZ_CP011308.1|WP_046550195.1|133076_133736_-|small-multi-drug-export-protein	unknown	unknown	gnl|CDD|377692
NZ_CP011308.1|WP_046550186.1|121770_123270_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046550190.1|127794_129075_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	unknown	unknown	gnl|CDD|235162
NZ_CP011308.1|WP_046550189.1|125955_127314_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046550198.1|142183_143584_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|224157
NZ_CP011308.1|WP_046550200.1|144519_146532_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NZ_CP011308.1|WP_046550201.1|146793_149394_+|Sec-dependent-nitrous-oxide-reductase	unknown	unknown	gnl|CDD|275078
NZ_CP011308.1|WP_046550193.1|131770_132115_+|hypothetical-protein	unknown	unknown	gnl|CDD|143585
NZ_CP011308.1|WP_046550191.1|129076_130135_-|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl|CDD|234638
NZ_CP011308.1|WP_046550197.1|136814_138092_-|MgtC/SapB-family-protein	unknown	unknown	gnl|CDD|379065
NZ_CP011308.1|WP_052746033.1|134597_135458_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP011308.1|WP_046550185.1|120871_121708_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|234698
NZ_CP011308.1|WP_046550196.1|135518_136805_+|chloride-channel-protein	unknown	unknown	gnl|CDD|238233

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP011308.1|WP_046550199.1|143700_144423_+|energy-transducer-TonB	gnl|CDD|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	2.79991e-22
NZ_CP011308.1|WP_052746034.1|138095_142064_-|HAD-IC-family-P-type-ATPase	gnl|CDD|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP011308.1|WP_046550192.1|130202_131687_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl|CDD|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
NZ_CP011308.1|WP_046550188.1|124427_125750_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl|CDD|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	3.27092e-131
NZ_CP011308.1|WP_046550187.1|123293_124280_-|tRNA-lysidine(34)-synthetase-TilS	gnl|CDD|366502	pfam01171, ATP_bind_3, PP-loop family. This family of proteins belongs to the PP-loop superfamily.	3.23475e-61
NZ_CP011308.1|WP_084721985.1|133940_134591_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.64776e-57
NZ_CP011308.1|WP_046550194.1|132195_132939_+|3-oxoacyl-ACP-reductase-FabG	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.39733e-123
NZ_CP011308.1|WP_046550195.1|133076_133736_-|small-multi-drug-export-protein	gnl|CDD|377692	pfam06695, Sm_multidrug_ex, Putative small multi-drug export protein. This family contains a small number of putative small multi-drug export proteins.	5.78329e-17
NZ_CP011308.1|WP_046550190.1|127794_129075_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	gnl|CDD|235162	PRK03815, murD, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional.	0
NZ_CP011308.1|WP_046550198.1|142183_143584_+|MBL-fold-metallo-hydrolase	gnl|CDD|224157	COG1236, YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis].	3.85199e-99
NZ_CP011308.1|WP_046550200.1|144519_146532_+|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	6.15585e-55
NZ_CP011308.1|WP_046550201.1|146793_149394_+|Sec-dependent-nitrous-oxide-reductase	gnl|CDD|275078	TIGR04246, nitrous_NosZ_Gp, nitrous-oxide reductase, Sec-dependent. This model represents the nitrous-oxide reductase protein NosZ as characterized in Geobacillus thermodenitrificans. In contrast to the related form in Pseudomonas stutzeri, this version lacks a recognizable twin-arginine translocation (TAT) signal at the N-terminus. Consequently, its accessory protein may differ. Some members of this family have an additional cytochrome c-like domain at the C-terminus.	0
NZ_CP011308.1|WP_046550193.1|131770_132115_+|hypothetical-protein	gnl|CDD|143585	cd07316, terB_like_DjlA, N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins. Tellurium resistance terB-like domain of the DnaJ-like DjlA proteins. This family represents the terB-like domain of DjlA-like proteins, a subgroup of heat shock DnaJ-like proteins. Escherichia coli DjlA is a type III membrane protein with a small N-terminal transmembrane region and DnaJ-like domain on the extreme C-terminus. Overproduction has been shown to activate the RcsC pathway, which regulates the production of the capsular exopolysaccharide colanic acid. The specific function of this domain is unknown.	0.00254225
NZ_CP011308.1|WP_046550191.1|129076_130135_-|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl|CDD|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	8.91507e-151
NZ_CP011308.1|WP_046550197.1|136814_138092_-|MgtC/SapB-family-protein	gnl|CDD|379065	pfam13194, DUF4010, Domain of unknown function (DUF4010). This is a family of putative membrane proteins found in archaea and bacteria. It is sometimes found C terminal to pfam02308.	2.09427e-58
NZ_CP011308.1|WP_052746033.1|134597_135458_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	8.97509e-25
NZ_CP011308.1|WP_046550185.1|120871_121708_+|tyrosine-type-recombinase/integrase	gnl|CDD|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	2.51315e-66
NZ_CP011308.1|WP_046550196.1|135518_136805_+|chloride-channel-protein	gnl|CDD|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	1.25982e-48

Protein sequences

>NZ_CP011308.1|WP_046550194.1|132195_132939_+|3-oxoacyl-ACP-reductase-FabG
MKFSGNNVLVTGASRGIGAQIAKTLAQMGLKVWVNYRSGEAEANTVKADIEAAGGKAEVIGFDVSNEEAFVAAIKSIVELDGELSYLVNNAGITNDKLAMRMKTEDFMSVIEANLKSTFIGCREAVKVMGKKRFGSVVNIASIVGETGNAGQTNYAASKGGTIAMTKSFAIEAAPRNIRYNTVTPGFIATEMTDVLKDEVKDAFTAKIPMGRFGEPKEVAEAVAFLLSDHASYITGETLKVNGGMYM
>NZ_CP011308.1|WP_046550193.1|131770_132115_+|hypothetical-protein
MEKKIKESVGTLLAHIIKVDHRDIEKEAPLFCKIMGQDFDCSPEEAKAFLYKIKDAEYDLDKHIEIINQALCDDKLSKFHLLEQLNHIIYSDEISEEDYKIFEDIKNKLFECDK
>NZ_CP011308.1|WP_046550192.1|130202_131687_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MELQKTVLIITDGIGYKPQGGCNAFEAAQKPTYDRLFKTAPYALISTHGLSVGLPEGQMGNSEVGHMTIGSGRVLYQDLVKISLALEDGSIEENQALKEILGESDRVHLIGLMSDGGVHSHIEHTIGFAKLAKRRGKRVFLHLITDGRDVSPTSAKCYIEQIEAICDEDISIATIGGRFYTMDRDNRWERVEKGYRAIAEATPKTTLSPEAYVDESYARNETDEFIEPVAFEGYDGMKEGDAVIVTNFRSDRVREITTALGDPDFDAFKRKFIPLHIATMTQYDASFPYPVLFPKEAPKNTLAEVIAHAGLRQLHTAETEKYAHVTFFLNGGIEEPMIGESRVLIPSPDVKTYDMKPEMSALQVGEAVRKAMDEAYEFIVVNFANGDMVGHTGNYDAARQAVETVDSELGKIIEKAKEDGYAVVLTSDHGNCEEMCDIEGHVLTNHTVGEVWCFILADGVDKVKEGGGLNNIAPTVLKLMGLDIPEEMDEPLIV
>NZ_CP011308.1|WP_046550191.1|129076_130135_-|phospho-N-acetylmuramoyl-pentapeptide--transferase
MLYELNNLLHMHLFGYISVRAGFAFLLAFLLVLILMPKYIAWAISKNANQPISKYVAAHASKSKTPTMGGAVFIIATVIAAFIVIDLENIYVWIGLFTLIGFGLVGFKDDIGKILSGDNLEGLTPRGKMGLQIIISLISTALLIYSGFPTEFYVPFVKTPLFDMGYFAIPFWILMFLAVTNAVNLTDGLDGLATVPSIISLISLGVIVYITGHAIISHYLLMPHIKGVGEVLVLTAALAGALMGFLWYNCYPAEIFMGDTGSLSIGGFLAYLAILGKSEVLLILIGFVFVMETLSVILQVGSYKLRKKRIFLMAPLHHHFELKEWAENKIIVRFWMIAFITNLLALITLKIR
>NZ_CP011308.1|WP_046550190.1|127794_129075_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase
MKPTLFGYGLTTKAIARKLGGGCTFFDDKTNEPYTDEMGNHIYPSSMFDPDKSELEVTTPSLKPDHPLIQKAKHLLSEYDYFLSPAGYCPPTAPGTPDCTNGAVRAQHPTHTKPFTVWISGTNGKTTTTQMLIHLLEKRGAVSGGNIGTPLADLDPDAPIWVLETSSFTLHHTRTASPNIYLLLPITPDHLDWHGTSEAYAADKLRPLLTMKEGELALVPKGLDLPETNAFIVEYDSIDFLSDYFNINPARINFKAAFLEDAMLALAITRVLFDEVDYERINTFKMDLNRQQKLHDAKGRLWVNDSKATNVDAAIQAIRAYDDHHIHLIAGGDDKGVDLHPFFDAMSQVSLTLYTIGTNSDRLLSLANEYNIEAVASKTLENAVTNIDKKMGTNDVALLSPAAASFDQFKNYAQRGEIFIDLVKKL
>NZ_CP011308.1|WP_046550189.1|125955_127314_-|hypothetical-protein
MKKTLLLSVVASTLIMAGGDIEPVAAPVVETSNWEWSGTAKLYYQTMDHENYTINGAVNPNARVVGDSNDMFDRRSSAADAGLQLRVANKDVIGGLGFGAELTAINTLNLVNYGVVTASMQSVGADANAADADDILSGAWVSQAYLTYGFGNTSIKVGRQELPKSLSPFAFSEGWNIFKNTFEAALIVNTDLPDTTLVGAYVNRANGSRSWAGSIVAITNAHDMTDWADVGEDGAYMLTAQNKSIANLTLTGSFYYAPSFVKATDMDVTIFWADAKYNNADFPVTVAVQGGVLDYDAIGATDTQTTAFGARIGGKVGPIALSAAYTSVDMEANSISVTNLGTGVKSPLYTQQVLNQVFIDGHNGDADTWQIKGVYKGLGGKFVAQYANSDTENDWNYGEFDFIYGTTFNTAYGDLGLKAMWINQDFDGAPKAGVNSGDDTNNVIRLIASYDF
>NZ_CP011308.1|WP_046550188.1|124427_125750_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MPSRKKLHLVSLGCTKNLVDSEVMLGRLKEYEITDNNTEADVIIVNTCGFIDAAKEESINTVLNLHDERKEDSILVMSGCLSERYKEELQQDMPEIDIFTGVGDYEKIDELIASKQSTFSPEVYLATETSGRVITGSNYHAYIKIAEGCNQSCSFCAIPSFKGKLHSRSLSSIEKEVRMLAEQGYYDFSFISQDSSSYGRDMDLKDGLIDLIKTVEAIEGVRSARILYLYPSTTTFELIDTIADSKIFQTYYDMPIQHIDDTVLKTMKRGFGEKKTIEVLEHMKSKPGAFLRTSVIAGHPGESQESFEKLCTFMEEFGFDRFNTFHYSNEETTTAYQMEQIPPEVIDERAEILGEIAERSTLRSLEKMVGKTVELVVDGESDEHEYLLSARPLQWAVDIDGEILINDTSDLPIEYGKMYEAKVTELVGDQLLATLIKPVR
>NZ_CP011308.1|WP_046550187.1|123293_124280_-|tRNA-lysidine(34)-synthetase-TilS
MLNIDTKNLQSKKNLLAFSAGIDSSALFFLLIENNIRFDITIVDYNIREQSKKELAHAKALAKEHKLFCHTIQAPMFDTHFESKARKFRYEFFESLIQTEGYDNLITAHQLNDQLEWLLMRLTKGAGVSELIGLKPVTYRENYTLVRPLLEYSKDELLTYLKENNHPYFIDESNIDVKYERNLFRKQFSDPLMANYKEGIKRSFDYLRKDKKSLEKDFETIFTEKKLKIIKLHTISAKIKAADLALKESGYLLSASQRQEIKKERSLVIGGKWALELKGHMLYIAPYLNNKMPKSFKEMCRLAKIPAKIRPYCFHQNIDVTHIQTVDS
>NZ_CP011308.1|WP_046550186.1|121770_123270_+|hypothetical-protein
MKNSSLLLLICISLAGAEEAPSLENYTMHQKISYEKISISDEEDMGLVGLGILFDLNEYWYGGVGLYGAVEGERGGFFTVGAESGLRYTPIKDFQLKSGLFLGAGGGGSAPQGGGLMLRPYIEGSYRSENFIFGLGVSHVNFPNGDIESTQLYVSAEVLTNGSYVKGHHFSNSALSALDNDLFGMREMEASFVVAHYVPSSDSLNVGGTTNTDPFTLAGIELDSFHSKSMYHFIQLSGAGGGQADGYMEVFGGLGYRYQLGALPLYFDAQGALGASGGGKVDTGGGLVYKVQAGLDARLTEHLTLGIKGGMVDAFNGTFKATAYSANIGYETAIMDHMPKSNDGYSVQPGAWIFRMIHKSHLNSDKLFKNAEKNGQVDLLGFAIDRYMNENCYLTGQTFWAYNGDAGGYAEGIMGVGYHSDPHGKFSLYAEALGGVGGGGGIDIGGGAFGSLGGGIVYHFDRAWEGQLGGSYVRSRNGTLSTYDIVFGVNYKFSLLEKK
>NZ_CP011308.1|WP_046550185.1|120871_121708_+|tyrosine-type-recombinase/integrase
MSSEQLKGFIEDFLEYLLDVRGYSETTVTTYEIALRQMSEVSHFYEEDGIRVLDITPFRFNIVKNSKKTIVKKLSAVRSFVKYLEDQCNVSVKLIADESIKVPQSLPKPIEEQYIEEVLSKANMEEKLLISMLYGLGLRISELSGLKLEDIKSGWIQIHGKGSKVRELPMMASLQRLIIEYVEQNGPKKYLFEKGNAPLNSAQLRYKLTKLFKKEGLKVTPHQLRHSFATHLLNHGARIADVSELLGHETMATTQIYTKLGSVRKMEEYMKAHPLADK
>NZ_CP011308.1|WP_046550195.1|133076_133736_-|small-multi-drug-export-protein
MKHEHSFFKHTEGKILIAGLGLLGLFVLLILLSALFSQKTAQTFLSITAANLIFGRMAGLSIGISAQMDTQLLILFNFFIESIMVLILYPLFVQSWNKLEIITYEPLHNFFERSQKTVKKYQPYIKKYGVPGLILFVLSPVAMTGPVVGSFIGYIIGFNHRKTLTTILSATLIAIILWVYLIGHFKDFLITYSHMISIGFLTVAILMGVWYLMKKYVLK
>NZ_CP011308.1|WP_084721985.1|133940_134591_+|response-regulator-transcription-factor
MVCILVLEDDQLFNETLEDFLEEEGYAVETAMDPYSALEMSYKQVFDLYLFDVNLPYENGFDLLQKLRQSGDTTPTIFLTSREDKSSLSEGFEKGADDYMKKPIDLDELLLRIQAVLRRQIRQERISIGEYSLDTAAKTLYLDGKTQDVTKKAIELLLLLIQAKGEVVSSDEIKSRLWAAGQSASDGALRVYITQLKKYFTENIVNVRGVGYRWAE
>NZ_CP011308.1|WP_052746033.1|134597_135458_+|HAMP-domain-containing-histidine-kinase
MKISNHKKQILLAALGYFSSVAILLSFLYWFLKNEGFSEVNFLVAVLLVLILAGGWGYIISSHILAPKAQLDANLSHLSSEILHELNIPVATIKANASMLKKHLQEEERSLKRLERIEASSDRLERLYEELVYSIQKEIHPIEKEEVTLYHLLHERIEAFKSFGRNSFHLDVGEMKIRVDRIGFEKMIDNLLMNAMKYSDKTSLISVVLDGNVLTISDEGVGMDEAELLKVYERYYQSDRKKEGKGIGLALVKAYCNDEGIGIQIKSKKGEGTSVLLDLSGVHVRT
>NZ_CP011308.1|WP_046550196.1|135518_136805_+|chloride-channel-protein
MIAKLIIATLLTGVISGFFITFYEMLIAFTTRLLFMGDPFETIPVLPTWYLYVVPTVAIFIVNYLISKDNYIREYGLTEIADSVSQNKLIINVKTLFLKVIASTLSVSSGYAVGTEGPSAGMGAMVAYQIHRLFNLPIMLVKMMISVGASSGIAAIFVSPLTGIVFSIENIAYQFIKQYIGYVILGSVIAFSISVKFLDSISFHSSLGKEFDYYYVMPILIFIPFITIFIYLYLFMKKRLLHIIDLEIFKKFRTMRNMVFSLIGGSVIGTILLIEPHAGFSGKEIVMHLINNKESISVYFIFLIIILRIVGTTVSLYANAVGGLFLPLMSIGALVGYGYGEIITFYSHFPFEPFFFAAVGSAVFMGVVMKLPLTAVVLALELTFDYNILVATGVSVVLVGYLTSLQFNIRRKYVTQAEESSGQTNGSH
>NZ_CP011308.1|WP_046550197.1|136814_138092_-|MgtC/SapB-family-protein
MDYVLVKSLLIAVLLGFAIGLQRTMSHLYSNDVGFAAGSRTFALISLLGFMSGWMYQFAPSIIVVASASIAGIIILSYYMKSIHYKKMGMTSQIAAIITYLLGLMAYFHLEQYAVFIGVIMIVLLDIKPRLQRIEKNITPTDLNASILLLAMTFLILPILPDEMIGPYKLFNPYKTWLMAVIIAAISFVGYIAIKILGNKQGVLLTGLFGGLISSTAVSISLSKMYTAQKEYLNNYAAGIAIACTLMYLRVLFEALVINMEVAWHLLLPYTLAALSGFAYVYIIYKQATQTAPGIQNEILNKNPLQLSEAIKFGILFGVIYGAITIVKQGYGDIGVYIVSSFSGITDVDAITLSLSQLEADNKLPILTAVNGIIIASVVNTYVKLGIVFWMGGRKLGIRVLWFVLLTTGMMGAGLWIDTVLPLTP
>NZ_CP011308.1|WP_052746034.1|138095_142064_-|HAD-IC-family-P-type-ATPase
MTSEIVGQFLLLLALLFGLTYILAGFMERLRIPGILAALFVAMGAHYTPIGDLLSHGIFNEIFTLLAELGVLFLLFFIGLQIDMQEMRSQSKNIIIATVLNTIIPFALGIAVMRYLGYDWMVSFVVGLTRMPTAEAVIVPILDEFNLIRTKVGNYIVGAGVLDDVIEVFLIAFVSLWIGDKSGLATNDSTAIIDLVLNIIIFIAAAWVVRKWILLPLSHWLKIRVANLILLMIIVLFVFGGFAERTDLGLVVGAIVAGMLMRPVFNTAGDVGVQATKAVRAVSYGFFGIVFFLWIGMSVDLSGMFKAPELAILLFLAAFVGKIIGIFLMVPMGQLNSKEAWTIGIGLNARLTTEIIVAKLLLDAQLIDTQLFTALVAASSVSTIVVPLLFSLMVSFWKETLMQSAVSKTKKKKIEKPEKEQIPWYAQKFDTVCKALGTDPQKGLSKDEIVQRQAHYGPNRIRSVHKEKWYWILFRQFTDVLIIILLIAAAISFAIGEIGDAVTIMIIVILNGILGFIQEYKAEKAIEALQKMLSLRCKVLRDGEKKEIDSTKLVPGDIVFLEIGDKIPADLRLIEAVNLKVDESALTGESVASLKNIKAVPQKSALGERSSMAWMGTNVVNGYAKGIVVATGMQTEFGKIAKMTSEVGSTQTPLQKKLAVLGKKLGIFSVAIAAFVAIIGYLLGKDMMEMFLTGISLAVAVVPEGLPAVVTITLALGVKAMVRQKALLRRLQAAEALGSANVICTDKTGTLTQNQMTVQKVWLFSGEIDVTGSGYDPKGHFEKDKKKVDYKKRQDLIELLKTGLICTHAGLTREKDAWKITGEPTEASLIVAAYKAWLTPEVDEKITTEFSFNSQRKRMSVIVQEKGKNIAYIKGAPEVLLERSNYYFDGEKVQALDAQKKKAFEDAYSQLARNGLRTLALAKRVLPKGIKLDADAVENDLVLLGVVGIIDPPRPEVHHAIQTARTAGINVVMITGDAPLTAMAIAKEVGLDARHGITGSQLDTLDDDALKNAIHEGAIFARTTPADKMRIIKILQDEGLVTAMTGDGVNDAPALKKADIGIAMGMRGTDVARGAADMILLDDNFASIINAVREGRRQYDNIKKFVTYLLSSNIGEVIAIFVNILLGGPLILLPVQILWMNLVTDGMTAVALGMEKAEKGVMHRPPRASSESFLQYRGIIMIILLGGYIGGATLWIFHHYLSSGLPEAQAIGLAQTAAFTAIIILEKMNVFNYRSLHAPIYTMGFFSNKWLIAAWITTVSLQVAAVYVPFLQEALHTVPLGWKDWLLIFEISLPIFVVTELYKITEWFLLKSKNAHTEKEGA
>NZ_CP011308.1|WP_046550198.1|142183_143584_+|MBL-fold-metallo-hydrolase
MATVVSYGAAEVVTGSCHLFTIDGGPRILVDCGMFQGQEEERNYGPFDFNPSEVDYLLVTHAHLDHVGRIPKLVKEGFTGKIYATHATHDLAEIILLDSAKIMKEDFNTKYKKAQRQGKEEGVMEPLYVEADVEDVFEFDWHYPEYDKSFTLEDDIEITYRDAGHILGAAFIEIRYKENGVDHTIVFSGDIGNDTEIVMKDLAPCTHADYLYVESTYGDRDHQGVEDTVTEFKSVIIKTMKDWGNVIIPSFAVERTQELLCILKQMHRRKELPQCKIFVDSPMATRATEVYRNYSELLSSECQEIKKEDGTIFDFENLVYTLDVEASKAINDMDTRAIIIAGSGMCNGGRILHHFKNRLWNKKNAVIFVGYQAVGTLGRHIVDGARWVKIYNEDILIKASIHTINGFSAHADQKGIVKWISQIEGLNSIYLVHGEEDKQVILRAVLENELHAKAHIVEPEEVIYLA
>NZ_CP011308.1|WP_046550199.1|143700_144423_+|energy-transducer-TonB
MVKHRNLVSFIITTLLYALLFGGYFYLMRTYIIADQAAQDSAIQLCLSEFVPEVVPEAQEAEEEPVVEEEPEPEPEPEPIVKEEPVVEKVIPEPVKPKVLPVPEVKKPKPKKKEIKKKKKVKKKKVRTRTAQSSRVGVKRRGSGHASVSQKNRFLSTVRQRINQNKSYPRIAKRRGMQGSVKVRFTILSNGHVGNISISGPKVFHSSARRAVEKAFPLSTKHIPVSLPKTVNLTLRYQLR
>NZ_CP011308.1|WP_046550200.1|144519_146532_+|TonB-dependent-receptor
MKKGIYLSLVCAASLYAAEAELGTIDVEAKVDTEVHKDVHGDDIKSADVAEALMKQSPSVMLVRRSGIANDIIVRGQKKDNINVTIDGAKIYGACPNRMDPPISHVLANNIDYITIDDGPFDVESFGALSANVDVETLKPTQEFHGDAALNFGSWNYKKASAMVSGGTERIRFLLSASAERGGQYEDGDGNDFAQQVDNYINNNLNGNMAHDKKLKGQAFLPQYRDMDAFTKKTVLAKVFWDITDNQQLKLSYTGNRSDDVLYPTTPMDALYDDSNIYNAEYVLNELGRYSKELDIQLYKSDVDHPMSNMYRKASSMMLMKNWLTTDTQGAKIKNRFDLDKHEITVGIDYSLRNWNGAYYGKNDMYKGVSIPDVDTRNIAFFTKDKIHFDKFDVDLGLRYDDTSVEPGLGTLQSNDYNALNGNILLTYHMDEKTKIFGGVGHSSRVPDGRELYFQKAGKVLGTPDLDLVTNTEFDIGGETQFEDATLKAKFFYSKLGDFIFYNADKMINRFENMDATLYGVEVSGSYIVTDTLYLDGALSFQKGEKKNPLSGQTGTNMPEIPPMKLVAGINFEEPGDYLLRAEVIAASAWDDYDAENGEQYLPGYAVLNLKGSKTFADHFEVTVGVDNLFDKTYAVSNTYEDLTLISGGGEVMLMNEPGRYIYTNLSYKF
>NZ_CP011308.1|WP_046550201.1|146793_149394_+|Sec-dependent-nitrous-oxide-reductase
MSYKLSKLTSLFLGSALSVSTLFGASALDNVMKERGLTQADLLAAAKTYTPSGGRDKYIVFSSGGQSGQIMVYGVPSMRILKYIGVFTPEPWQGWGYDDDTKKVLAQGNIRGKKITWGDTHHPALSETNGRYDGKWLVINDKANPRLAVIDLKDFVTKQIVVNPVFKSDHGGAFFTPNSEYILEACQYGAPLDNNYHPIEEYKETYRGGVTVWKFDPKIGRIDPKKSFTIEMPPYMQDLSDAGKEASFGWGFTNSFNSELYTGGIEKGLPPFEAGMSRNDTDFLHVYNWKKLAELAKDPKNVKMINGTRVVPMEVAIKNDALFLIPEPKSPHGVDVSPDGKSIVVCGKLDTHATVYDFDKIQDAIKHKAYVGKDPYGIPILDLKKTMHCQAELGLGPLHNQYGKNWKDGEIYTSLYVDSQVVKWNYKTCKVEDRQNVNYNIGHLCGMEGKTEDPQGDYIIALNKLAIDRFNEIGPLHPQNHQLIDIRGKKMQLLYDMPVPLGEPHQAVAIRASKLKTEVRYKMGTNAFTGKVHEGKTLAGQEKIVRKGNHVYVYGTVVRSHINPEHVTVNKGDTVTFYLTNLERAEDETHGFTVDTYNVHTSLEPGKTVAVTFKADLEGVFPYYCTEFCSALHLEMMGYLLVKDPNKKYTAAKKLKMAAMSPEQLKKEYDQTVAVNNATDKVIQSVVKFLKENHYEKYPTIKALVTDALDQYGKIAEQKKKSDEAVKAGDLDKAILFENMIWQYMVKTADVGIRAKDLLVKKVAKPMSPAAKRGEAAYLEGGCNGCHVIGKVSSGPDLTGVLQRHENGEAWAKQWIMHPEKMYDDDYIKSMINYFNLRMPNQGMTEEQTNDIIEYLKWIDENANLF

Crispr_ID: NZ_CP011308_2

• CRISPR_ID: NZ_CP011308_2
• CRISPR_location: 995263-996939
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 24 spacers
• Cas_protein_info: cas2,cas1,cas9,WYL,DEDDh

Consensus repeat of NZ_CP011308_2

Consensus_repeat	Method
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CRISPRCasFinder
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CRT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	PILER-CR

spacers of NZ_CP011308_2

>2.1|995299|87|NZ_CP011308|CRISPRCasFinder
AACCTTCATTTTATCAAAAATTTCATAAAAAGACAATAGATTTAAGAAAAATAGATAATTTTTTAGAAACTTAGAAAATTTTTAATA
>2.2|995422|30|NZ_CP011308|CRISPRCasFinder,CRT
AGATGTGCCCGCCCCTATGTCGTTGGTTGA
>2.3|995488|30|NZ_CP011308|CRISPRCasFinder,CRT
GATTTTAAGGTGATATCTCTTGCCGGCTAT
>2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT
GTGACATGCTCCAAGGCGGTTATCCTGCCA
>2.5|995620|30|NZ_CP011308|CRISPRCasFinder,CRT
AAAGAAAATTATCGACAACATGACATCTGA
>2.6|995686|30|NZ_CP011308|CRISPRCasFinder,CRT
ATACCCCATCTGGGGCAGTTGCTGTAGGTT
>2.7|995752|30|NZ_CP011308|CRISPRCasFinder,CRT
AGAAACAAAGTCGATCAGTACGAAAAAGAG
>2.8|995818|30|NZ_CP011308|CRISPRCasFinder,CRT
CAAAGACAACGGATGGATAGACCTTATATC
>2.9|995884|30|NZ_CP011308|CRISPRCasFinder,CRT
TCATTTTGACACTACTTTCTGGCGGGTTGT
>2.10|995950|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
AGTAAACGATGGAATAGTCACCCGCGCAGG
>2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
TTGGAGATAGAGGAGCATAACAAAAACAGG
>2.12|996082|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
CTATAATCACGACTAGCCCGCGCCCAAATC
>2.13|996148|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
CGTAGAATACCGCGTTAGGTACTTCCAGTT
>2.14|996214|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
GATATCCGGTGTTGCCGTACCGTCAAGATT
>2.15|996280|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
TCACGCGGTGGGTATCGCGTTCGCTATGCT
>2.16|996346|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
AGATGTTAGCGGGGACAGCGCAGAAACCGT
>2.17|996412|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
TCACGCGGTGGGTATCGCGTTCGCTATGCT
>2.18|996478|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
GATCGTTAATGAGGTTCCCGAAGCGGTCCT
>2.19|996544|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
CATGTTTTCATAAACGCGGTCCACCATTTC
>2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
ACTTTAATTATTAAGGAGATATAGAATGGC
>2.21|996676|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
CGGTGATGGGATAATGTCAAAAATAATCAT
>2.22|996742|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
GGCACTACTGAATTTGGCAATGACTACTAC
>2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
GAAAAAGAGATTGATATACTGTATAATATG
>2.24|996874|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR
AAAGAAAATAATCGACAACATGACATCAGA

CRISPR arrays and Neighbor proteins around NZ_CP011308_2

CRISPR arrays

The CRISPR arrays of NZ_CP011308_2

>merge|NZ_CP011308|2|995263-996939|CRISPRCasFinder,CRT,PILER-CR
TTTTAAGACCCCTCTTAAACCGCCACCTGTTATAACAACCTTCATTTTATCAAAAATTTCATAAAAAGACAATAGATTTAAGAAAAATAGATAATTTTTTAGAAACTTAGAAAATTTTTAATAGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATAGATGTGCCCGCCCCTATGTCGTTGGTTGAGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATGATTTTAAGGTGATATCTCTTGCCGGCTATGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATGTGACATGCTCCAAGGCGGTTATCCTGCCAGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATAAAGAAAATTATCGACAACATGACATCTGAGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATATACCCCATCTGGGGCAGTTGCTGTAGGTTGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATAGAAACAAAGTCGATCAGTACGAAAAAGAGGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATCAAAGACAACGGATGGATAGACCTTATATCGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATTCATTTTGACACTACTTTCTGGCGGGTTGTGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATAGTAAACGATGGAATAGTCACCCGCGCAGGGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATTTGGAGATAGAGGAGCATAACAAAAACAGGGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATCTATAATCACGACTAGCCCGCGCCCAAATCGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATCGTAGAATACCGCGTTAGGTACTTCCAGTTGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATGATATCCGGTGTTGCCGTACCGTCAAGATTGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATTCACGCGGTGGGTATCGCGTTCGCTATGCTGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATAGATGTTAGCGGGGACAGCGCAGAAACCGTGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATTCACGCGGTGGGTATCGCGTTCGCTATGCTGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATGATCGTTAATGAGGTTCCCGAAGCGGTCCTGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATCATGTTTTCATAAACGCGGTCCACCATTTCGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATACTTTAATTATTAAGGAGATATAGAATGGCGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATCGGTGATGGGATAATGTCAAAAATAATCATGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATGGCACTACTGAATTTGGCAATGACTACTACGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATGAAAAAGAGATTGATATACTGTATAATATGGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAATAAAGAAAATAATCGACAACATGACATCAGAGTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT

>NZ_CP011308|2|2|995263-996939|CRISPRCasFinder
TTTTAAGACCCCTCTTAAACCGCCACCTGTTATAAC	AACCTTCATTTTATCAAAAATTTCATAAAAAGACAATAGATTTAAGAAAAATAGATAATTTTTTAGAAACTTAGAAAATTTTTAATA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGATGTGCCCGCCCCTATGTCGTTGGTTGA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GATTTTAAGGTGATATCTCTTGCCGGCTAT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GTGACATGCTCCAAGGCGGTTATCCTGCCA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AAAGAAAATTATCGACAACATGACATCTGA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	ATACCCCATCTGGGGCAGTTGCTGTAGGTT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGAAACAAAGTCGATCAGTACGAAAAAGAG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CAAAGACAACGGATGGATAGACCTTATATC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TCATTTTGACACTACTTTCTGGCGGGTTGT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGTAAACGATGGAATAGTCACCCGCGCAGG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TTGGAGATAGAGGAGCATAACAAAAACAGG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CTATAATCACGACTAGCCCGCGCCCAAATC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CGTAGAATACCGCGTTAGGTACTTCCAGTT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GATATCCGGTGTTGCCGTACCGTCAAGATT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TCACGCGGTGGGTATCGCGTTCGCTATGCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGATGTTAGCGGGGACAGCGCAGAAACCGT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TCACGCGGTGGGTATCGCGTTCGCTATGCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GATCGTTAATGAGGTTCCCGAAGCGGTCCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CATGTTTTCATAAACGCGGTCCACCATTTC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	ACTTTAATTATTAAGGAGATATAGAATGGC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CGGTGATGGGATAATGTCAAAAATAATCAT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GGCACTACTGAATTTGGCAATGACTACTAC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GAAAAAGAGATTGATATACTGTATAATATG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AAAGAAAATAATCGACAACATGACATCAGA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT

>NZ_CP011308|2|1|995386-996939|CRT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGATGTGCCCGCCCCTATGTCGTTGGTTGA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GATTTTAAGGTGATATCTCTTGCCGGCTAT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GTGACATGCTCCAAGGCGGTTATCCTGCCA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AAAGAAAATTATCGACAACATGACATCTGA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	ATACCCCATCTGGGGCAGTTGCTGTAGGTT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGAAACAAAGTCGATCAGTACGAAAAAGAG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CAAAGACAACGGATGGATAGACCTTATATC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TCATTTTGACACTACTTTCTGGCGGGTTGT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGTAAACGATGGAATAGTCACCCGCGCAGG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TTGGAGATAGAGGAGCATAACAAAAACAGG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CTATAATCACGACTAGCCCGCGCCCAAATC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CGTAGAATACCGCGTTAGGTACTTCCAGTT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GATATCCGGTGTTGCCGTACCGTCAAGATT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TCACGCGGTGGGTATCGCGTTCGCTATGCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGATGTTAGCGGGGACAGCGCAGAAACCGT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TCACGCGGTGGGTATCGCGTTCGCTATGCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GATCGTTAATGAGGTTCCCGAAGCGGTCCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CATGTTTTCATAAACGCGGTCCACCATTTC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	ACTTTAATTATTAAGGAGATATAGAATGGC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CGGTGATGGGATAATGTCAAAAATAATCAT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GGCACTACTGAATTTGGCAATGACTACTAC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GAAAAAGAGATTGATATACTGTATAATATG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AAAGAAAATAATCGACAACATGACATCAGA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT

>NZ_CP011308|2|1|995914-996939|PILER-CR
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGTAAACGATGGAATAGTCACCCGCGCAGG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TTGGAGATAGAGGAGCATAACAAAAACAGG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CTATAATCACGACTAGCCCGCGCCCAAATC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CGTAGAATACCGCGTTAGGTACTTCCAGTT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GATATCCGGTGTTGCCGTACCGTCAAGATT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TCACGCGGTGGGTATCGCGTTCGCTATGCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AGATGTTAGCGGGGACAGCGCAGAAACCGT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	TCACGCGGTGGGTATCGCGTTCGCTATGCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GATCGTTAATGAGGTTCCCGAAGCGGTCCT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CATGTTTTCATAAACGCGGTCCACCATTTC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	ACTTTAATTATTAAGGAGATATAGAATGGC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	CGGTGATGGGATAATGTCAAAAATAATCAT
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GGCACTACTGAATTTGGCAATGACTACTAC
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	GAAAAAGAGATTGATATACTGTATAATATG
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT	AAAGAAAATAATCGACAACATGACATCAGA
GTTTTAAGACCCCTCCAAACCGCCACCTGTTATAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011308.1|WP_046550870.1|987552_988461_+|PDC-sensor-domain-containing-protein	unknown	unknown	gnl|CDD|350341
NZ_CP011308.1|WP_084722092.1|997339_999400_-|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl|CDD|236645
NZ_CP011308.1|WP_046550877.1|1000857_1001406_-|6-phospho-3-hexuloisomerase	unknown	unknown	gnl|CDD|240138
NZ_CP011308.1|WP_046550869.1|986721_987537_+|phosphatidylserine-decarboxylase	unknown	unknown	gnl|CDD|235177
NZ_CP011308.1|WP_046550878.1|1001407_1002037_-|3-hexulose-6-phosphate-synthase	unknown	unknown	gnl|CDD|132172
NZ_CP011308.1|WP_046550868.1|985895_986729_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046550866.1|984590_985325_-|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|181186
NZ_CP011308.1|WP_084722028.1|993946_994864_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|274694
NZ_CP011308.1|WP_046550881.1|1005297_1005873_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP011308.1|WP_046550872.1|989538_990441_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NZ_CP011308.1|WP_046550882.1|1006099_1006426_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046550876.1|999488_1000607_-|FIST-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|378436
NZ_CP011308.1|WP_046550871.1|988469_989093_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|372595
NZ_CP011308.1|WP_154806468.1|1002222_1003524_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046550867.1|985435_985894_+|iron-sulfur-cluster-assembly-scaffold-protein	unknown	unknown	gnl|CDD|143480
NZ_CP011308.1|WP_046550879.1|1003698_1004121_+|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|181730
NZ_CP011308.1|WP_046550875.1|994850_995183_+|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043
NZ_CP011308.1|WP_046550873.1|990546_993978_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|187774
NZ_CP011308.1|WP_046550880.1|1004428_1005007_-|rRNA-pseudouridine-synthase	unknown	unknown	gnl|CDD|224108
NZ_CP011308.1|WP_052746095.1|1004117_1004432_+|hypothetical-protein	unknown	unknown	gnl|CDD|225876

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP011308.1|WP_046550875.1|994850_995183_+|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	1.3e-26	87.8	0.7
NZ_CP011308.1|WP_046550872.1|989538_990441_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	1.5e-32	107.7	1.0
NZ_CP011308.1|WP_084722028.1|993946_994864_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	2.9e-72	237.8	0.0
NZ_CP011308.1|WP_046550873.1|990546_993978_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	6.9e-57	188.1	25.3
NZ_CP011308.1|WP_046550866.1|984590_985325_-|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	5.2e-31	102.7	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP011308.1|WP_046550870.1|987552_988461_+|PDC-sensor-domain-containing-protein	gnl|CDD|350341	cd18773, PDC1_HK_sensor, first PDC (PhoQ/DcuS/CitA) domain of methyl-accepting chemotaxis proteins, diguanylate-cyclase and similar domains. Histidine kinase (HK) receptors are part of two-component systems (TCS) in bacteria that play a critical role for sensing and adapting to environmental changes. Typically, HK receptors contain an extracellular sensing domain flanked by two transmembrane helices, an intracellular dimerization histidine phosphorylation domain (DHp), and a C-terminal kinase domain, with many variations on this theme. HK receptors in this family contain double PDC (PhoQ/DcuS/CitA) sensor domains. Signals detected by the sensor domain are transmitted through DHp to the kinase domain, resulting in the phosphorylation of a conserved histidine residue in DHp; phosphotransfer to a conserved aspartate in its cognate response regulator (RR) follows, which leads to the activation of genes for downstream cellular responses. The HK family includes not just histidine kinase receptors but also sensors for chemotaxis proteins and diguanylate cyclase receptors, implying a combinatorial molecular evolution.	2.20434e-10
NZ_CP011308.1|WP_084722092.1|997339_999400_-|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	2.26231e-133
NZ_CP011308.1|WP_046550877.1|1000857_1001406_-|6-phospho-3-hexuloisomerase	gnl|CDD|240138	cd05005, SIS_PHI, Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with formadelhyde to become hexulose-6-phosphate, which is then isomerized to fructose-6-phosphate by PHI.	1.48484e-70
NZ_CP011308.1|WP_046550869.1|986721_987537_+|phosphatidylserine-decarboxylase	gnl|CDD|235177	PRK03934, PRK03934, phosphatidylserine decarboxylase; Provisional.	3.17709e-156
NZ_CP011308.1|WP_046550878.1|1001407_1002037_-|3-hexulose-6-phosphate-synthase	gnl|CDD|132172	TIGR03128, RuMP_HxlA, 3-hexulose-6-phosphate synthase. Members of this protein family are 3-hexulose-6-phosphate synthase (HPS), or the HPS domain of a fusion protein. This enzyme is part of the ribulose monophosphate (RuMP) pathway, which in one direction removes the toxic metabolite formaldehyde by assimilation into fructose-6-phosphate. In the other direction, in species lacking a complete pentose phosphate pathway, the RuMP pathway yields ribulose-5-phosphate, necessary for nucleotide biosynthesis, at the cost of also yielding formaldehyde. These latter species tend usually have a formaldehyde-activating enzyme to attach formaldehyde to the C1 carrier tetrahydromethanopterin. In these species, the enzyme is viewed as a lyase rather than a synthase and is called D-arabino 3-hexulose 6-phosphate formaldehyde lyase. Note that there is some overlap in specificity with the Escherichia coli enzyme 3-keto-L-gulonate 6-phosphate decarboxylase.	2.18352e-81
NZ_CP011308.1|WP_084722028.1|993946_994864_+|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	3.99404e-80
NZ_CP011308.1|WP_046550866.1|984590_985325_-|DNA-polymerase-III-subunit-epsilon	gnl|CDD|181186	PRK07983, PRK07983, exodeoxyribonuclease X; Provisional.	8.93764e-38
NZ_CP011308.1|WP_046550881.1|1005297_1005873_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.36972e-06
NZ_CP011308.1|WP_046550872.1|989538_990441_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	6.79982e-28
NZ_CP011308.1|WP_046550876.1|999488_1000607_-|FIST-C-terminal-domain-containing-protein	gnl|CDD|378436	pfam10442, FIST_C, FIST C domain. The FIST C domain is a novel sensory domain, which is present in signal transduction proteins from Bacteria, Archaea and Eukarya. Chromosomal proximity of FIST-encoding genes to those coding for proteins involved in amino acid metabolism and transport suggest that FIST domains bind small ligands, such as amino acids.	3.36889e-21
NZ_CP011308.1|WP_046550871.1|988469_989093_+|HAD-family-hydrolase	gnl|CDD|372595	pfam13419, HAD_2, Haloacid dehalogenase-like hydrolase.	2.30471e-61
NZ_CP011308.1|WP_046550880.1|1004428_1005007_-|rRNA-pseudouridine-synthase	gnl|CDD|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	3.49147e-50
NZ_CP011308.1|WP_046550867.1|985435_985894_+|iron-sulfur-cluster-assembly-scaffold-protein	gnl|CDD|143480	cd06664, IscU_like, Iron-sulfur cluster scaffold-like proteins. IscU_like and NifU_like proteins. IscU and NifU function as a scaffold for the assembly of [2Fe-2S] clusters before they are transferred to apo target proteins. They are highly conserved and play vital roles in the ISC and NIF systems of Fe-S protein maturation. NIF genes participate in nitrogen fixation in several isolated bacterial species. The NifU domain, however, is also found in bacteria that do not fix nitrogen, so it may have wider significance in the cell. Human IscU interacts with frataxin, the Friedreich ataxia gene product, and incorrectly spliced IscU has been shown to disrupt iron homeostasis in skeletal muscle and cause myopathy.	6.08279e-23
NZ_CP011308.1|WP_046550879.1|1003698_1004121_+|aminoacyl-tRNA-hydrolase	gnl|CDD|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	1.84263e-68
NZ_CP011308.1|WP_046550875.1|994850_995183_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	6.93095e-23
NZ_CP011308.1|WP_046550873.1|990546_993978_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl|CDD|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	2.1337e-48
NZ_CP011308.1|WP_052746095.1|1004117_1004432_+|hypothetical-protein	gnl|CDD|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	2.53683e-09

Protein sequences

>NZ_CP011308.1|WP_046550875.1|994850_995183_+|CRISPR-associated-endonuclease-Cas2
MSAFRIMWLIVMFDLPTQTKKDRKRYRWFSKHLDTESYIRLQYSIYAKVFNSIESANYGKKRLRNFLNTNVKKGNVRILMFTDAQFGKMEIIIGEQSSQEEIVQPTLFDF
>NZ_CP011308.1|WP_084722028.1|993946_994864_+|type-II-CRISPR-associated-endonuclease-Cas1
MASWKTIRITKPCRLRIDNGNLLVEDDELRFKLSLEDTDSIVFEGDRFMISAKVLSALSHYKIATLFCDEYYLPSAILHPYHQSSLATKTLKAQLAVTPSYADKLWQRIIIAKIGQQREVLEILGKEAEKLKLYITQVREADKYGAEAKSAKYYWNRLFDQLVREPDSFDIRNQALNYAYALVRSLLTRDLSAAGFLPALGIWHDNKYNAFNLSDDLIEPFRPILDIGVYRILEFHPDEEVLTPQMKKELINLLDIVYIEYEKGSSSLRNVSRLYVQFFKRSVEQGDAELLSFPVFDIKKLDECL
>NZ_CP011308.1|WP_046550873.1|990546_993978_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MSKKILAVDLGITSFGFSVLKEVEENSYINIDNSVIMRDAPYDKDGKSKQTSRREQASQRSLGEKRRQRIKEVAKTFNSFGVLSYDECMQVQKNNTITDKWKLRAEDALYRILSPQELFAIMAHMAKHRGYKSIATEDLLYELELELGLVEEQTEEEDSKTDEKRQVYAALGRLKRLKETYKVDTIAQVIHKAIQEGKFRSYRNHDDYEKMVRREDIEYEIETIIKKQCELGAFAFDGERCLQFIEVLHEAITDQIMPENDESLFGQCSYYANEKAAPRYSYLYDIYRLYKTLADLKIDYYDLTQEDRDKIVDFVIQKIAKGKNLKQVYYKDIRKILGLSNEQKLYGKDDQVVIKGKSSQRTLIKFFFLNEIGKFPTLMQKILSHTEALNIFAQLAEVVRFHKTPKLALAALHELLEPYGIEVEATELLALIKSKSAGTLSISHRFILDALPYFNEGKDESFVKEILGISPSEDYNTYPKSLKYLHLGKDNLFEKTQNAINNHAVKSLASWALQNIADLSWRYGSFDEIIIESARDVLPQVIKDAIEKSMKERGKEIDKIIESYKKEFPSMDRKMARKIKLLESQKFIDIYSGEVINISDLFNGRADIEHVVPRSLGGLSTDYNLIIANSDTNMQKSNRLPMDWLSGDIEYVKRVEMLFNGHKINWKKRKNLLATSLDEIYVEVQDTKALRATSYLESLVSEVLKMYYPFPNKEHRKNGVAVRNVPGKTTSKTRSWLGIKSKSRDTNFHHAEDALILATLNRGWQNRLHRMLKENYGKSEEELQLLWQKYTPHIEGVAIAGYIKEAYERFMSKGEESLWYRDMFGSIRSVSYWVSKKPLSASSHKDTVYSSRHRNPNNPDKVVPTVRKSILGAFNGLDILKNRHKWNKEEFLKVYDKEIRQKLWLYRLDNTNDPVYRAIEERANTIGNLIEIYIYKDPQHDKAVDEVYQEVIRSLLQKPITAAGKPVYKTVFVDDTFLPIEIERGESNKVLVRTDDNFLAVMFEKGEKEKLNISKVDVNSLHRLKKENAMIVYLNEVIYLFNKKKIIHYGALRSFKILSSGARYISLFNPRFPANPSSQPKKFTDGKSIKSISIGSTTGVIKVHLDLNGKMKSYQKFGFIPKELEAQFLKESGYGIVEDDTNH
>NZ_CP011308.1|WP_046550872.1|989538_990441_+|WYL-domain-containing-protein
MSHKKHPQPVKRIVDIVRRLYAFERLRASEISKEYEVSTKTIGRDMKKISEIIPLLSGRGVYHVDTEKMLHLSRLPSAMLHSFASNAGMSIECLGGSTSAIPVISFAIAYDGIPKQIAEQIIQSMEKECKCRFDYTNNRGISSLRTVSPIKLYTAKGKWYLLAKDDTSKEVRPFDFLKIRQFEILPGVPNDLTRSEIEEVNERASIWASAGQKPFEVRLHVSAYAKRYLMEVPLHKSQTLESPHTDGTATFTYQITHNMELLPEIKNWIPHIQVIEPKEFRDVLKKDVEKYLAEMDNMDI
>NZ_CP011308.1|WP_046550871.1|988469_989093_+|HAD-family-hydrolase
MKSKLIIFDMDGTLVNSSLTIANAINYVRQNLGFEPMEQEYILKHVNDHTINPAQFFYHSKRFDPDHERWFSEYYTKNHEKELVLYDGIRELLDALKEKGHALGVATNAYRGSTIESLTHLGVHDHFDAIACYDDVAQGKPHPDMLYKLLEETNTEKEKAHFVGDGPRDEMASQKAGIPYTMVDWGFTEHTDAVRSVKELEKILLRV
>NZ_CP011308.1|WP_046550870.1|987552_988461_+|PDC-sensor-domain-containing-protein
MLMVKEIQEYAQIRTKARAYLCYIMSRNISQNMESGTLESVIKKIEHLQEALPQSEVIYAIDGNGIQIIDNISKNSKLRGFGKGEDRSDRAYYYKTLQEHRCVLTDPYPSLVSNALVVTATFPLYDKDDNLLAIICVDITLKNILKMVHPSSIDSNFGILSKWIYTAFAAALFAVALLLFFKGVADFLHFGVNFADIDINKIFKSTILLTLSLAIVDLTKAIFEEEVLGRVKKKESTDDTHQTMVRFLGSIIIALSIEALMLVFKFALTDPGKLLYAVYLLVGIGVLILSLSVYLKVNQKNK
>NZ_CP011308.1|WP_046550869.1|986721_987537_+|phosphatidylserine-decarboxylase
MAKHFTSVISHYFGKFASKEFPPSVQCFINTAYVKLMGLDMSEFREPCSYKTLNKLFTRALEKPRALPEDENILISGVDALITDAGTIKEGKAYQIKGMSYGIEELFGAYHQEAAAKVEGGEFINFYLSPKDYHRYHIPMRLKVNSLTHIPGKHYPVNFPLLRNMKDLFIENERVVIECEDAKGRMQVLVLVAALNVGQMVVTFEEKVRTNSEIREPVHYTYEDLWVERGEFYGWFEMGSTILTFSEKGSIVPEVAINQKVSYGDALGRIC
>NZ_CP011308.1|WP_046550868.1|985895_986729_+|hypothetical-protein
MKTVAIKTHEAWLATLMAGFMSKTENKQVLFDFSDILFRHFTWLENEMITLNESYSYDRDIIPIKVEKLSDMLHDIVKRLDEIDLQLLSSPDKDLDARISSDIHYMRGVLKKMDDETVTAFSMERKFPGIELTEEATDALTLFLFEETYKEYELIMIYNYLKAHSNDAYMNRIFQILIEESFFHLKSFGDMGAKMGILAVPRVVMKELYQVTDVVQFLKDGINEELAAKEECKKLSEAVAKDSDELAKFFDFINHQENYHISLMTDALAHYAKAANG
>NZ_CP011308.1|WP_046550867.1|985435_985894_+|iron-sulfur-cluster-assembly-scaffold-protein
MTMDAQVIEHMMNPKNYGALPGANAEGMGKNPENGEKVAVYLRIETDEDEPYIGDIKFQAIGCTTTVVAGSMLTEEARGLNLNGAYNLVDATMKLLEKLPAEDAACSEMVALAIKAAVDTYVKRQEDPSYPVITYQVANSCVPKEENKEEGK
>NZ_CP011308.1|WP_046550866.1|984590_985325_-|DNA-polymerase-III-subunit-epsilon
MAKYVLFDTETTGNQEADRIIQIGAMIVHSKDEIEVFDELCSTQVPISIEAMEVHNITPDVIADKPAYSETAFARRVQELNTTENYLIAHNISFDLGMLEKEGFVNHYTLIDTVRCAKHLLPDSPYHRLQYLRYSLGLYKTEAQEAQKLGITIKAHDAIGDVLVMKLLLSKLVTLTQERFPGINPMQKMAELTQTPVLMKTFKFGKYKDREIEEIAREDRGYLQWMRNNLDLDEDMKYTLDQYL
>NZ_CP011308.1|WP_084722092.1|997339_999400_-|bifunctional-diguanylate-cyclase/phosphodiesterase
MVLSRLNCSSVSIYQKKDNKFELLYAKPKVLVRNKDYVSVVKELEEKYYHGCSHTPILFEKSNNQYYFFELNNFGYLILTKSANPLDELIVKSLEKINLKLLHAIQACIDHAEQKHLEQEIQKESALLKTVIDTVPIRIFWKDLESRYLGANKLFAEDANLQDVDQLIGKNDYDMPWKNEADLYRKMDKDIIDTGIAELNIEEPLTDKEGKHKWVSKFKVPLIDKNGKTFGILGAYMDITHKKENEKNLKLQRDALEHQAYHDTLTGLPNRLLFLDRLNQYIHKAHRNKQKVAVLFIDMDRFKEINDSLGHVFGDEAIKEVAQRIEGQIRETDTIGRFGGDEFIMIFNDISDPIVVVNIVQKIMQSMHDPIMIGGHSIYVTLSIGISIYPEDAETADDLLKNADAAMYRAKEDGRNTYKFYTEDMTQKVFERIALESKLRQSIKDENFMLYFQPQINGKDNRIMGIETLIRWEDGHKNFISPATFIPVAEETGLIIPLGQWILRSGMQQIVKWHADGLYPGRLAINISMLQLQKHDFISILEMLLEETGCQPQWLEIEVTESQIMKNPEQMILILQKINKLGISLSIDDFGTGYSSLSYLKRFPIDTLKIDQSFVKDLSDNEEDKAITKAVIALAESLNLRVIAEGVETEEQKSFLVSNGCINIQGYLYAKPMPADEMEKMLRGSL
>NZ_CP011308.1|WP_046550876.1|999488_1000607_-|FIST-C-terminal-domain-containing-protein
MADIIFDPTGSIESFTSNMNILSSENESVMILACDANGFKKELVDPILLKHTVSIIGGIFPSVIYNDKKYDKGTIFIGLNDKIQVNVIQGISQKNDDELDADMEKQIGDFDESVKTMFVYIDGLTKHIGKCINVLFDNYGLGINYIGGGSGSLSFEQKPSLFTNHGLIQDALVYAYSKRQSSIGVSHGWKSISGPYQVTKSEATILKELDYKPAFEVYKNIVDQYSSEPINADNFFNVAKSFPCGINTLSDEKIVRDPIILNGTEIICVGNIEEGNYVDILSGDNDSLIKAARHAAYISKENMHFKNDFTLFIDCISRVLFLKEDFCDEIKVVCKNNMPLVGAMTFGEIANDGKNYLEFFNKTSVVGHIGHG
>NZ_CP011308.1|WP_046550877.1|1000857_1001406_-|6-phospho-3-hexuloisomerase
MVAKRLIQQLKYGLKNADENNFNEFIEFFLQNKRIFVTGEGRSGLVGKFFAMRLMHLGNDVFVLGEINTPSIQKGDILVCISASGTTSSVVNSATTAKKHGATILAITANPKGLLKNLADFTVMIDTRNKKKRKKQNINDRKPPLGTLFELSSLLYLETLISEIMYICKIDEETMRARHVNI
>NZ_CP011308.1|WP_046550878.1|1001407_1002037_-|3-hexulose-6-phosphate-synthase
MKLQLAIDVLTTDEAFALVQETRKYIDIIEIGTPLIKHEGIKLVKSMRTLFPEKTLLVDLKTMDVGEYEANYCFEAGADIVTVLGVADINTIKGTIKSAKKHGKKALVDMINVPNKTALAKKVNKLGADFVGIHSGIDQQNAGQSPLSDLKEVSKNVKIPLAVAGGINLDTIDDIVKLKPEIIVVGGAITGTKDPKKAAKAIAKRIKGK
>NZ_CP011308.1|WP_154806468.1|1002222_1003524_+|hypothetical-protein
MGNFSLRAGYIGGICAITFLLATTQIQASWGATPLEDKYRPARAWIEKFSSTPDIVAAGSIADAIESCDDVVGKNGYCVVEVGDSASGLPLEIFRSNTKLQGKANMSPLTSSKNGTFIYIGDNTKRVVIEGLDIQGHSAGNHGIYGIIVEGENIKNILIRNNRIHDFNSNSNAHGIAVYGTAESNKRSIANVIIEGNTVYDMRTGSSESIVVNGNVKKWEIRNNDIYDINNIAIDAIGGEGTSPSRTNSEGRVLPGKLDAARYGFIEDNFVENMHTTDNPAYGSKESWAAAIYVDGGHHIQIRDNVVQNTAWGYEVGAENCMVSRQITMTGNSAEESYYGDLLLGGYAHKGFKADKSIDCDPYNTVDANEGHGYVKYLTVKENLFNSDPVEPDNVTLQYRTTNAIIIEPGVEPVNDQGNGSARGDENAVRTTE
>NZ_CP011308.1|WP_046550879.1|1003698_1004121_+|aminoacyl-tRNA-hydrolase
MANLKISNTATLDENEIEITAIRAQGSGGQKVNKVSAAIHLRFDISASSLPEFYKEKLLSLKDKRISKDGIVVIKSQQHRSQEQNREEALERLVELIKSVAVTQKKRVPTKPTKGSVNRRLNSKKKHAGKKRLRGKVERE
>NZ_CP011308.1|WP_052746095.1|1004117_1004432_+|hypothetical-protein
MKNQSDHNSKITIIIRFWNDIRALAGLIRAYWKNEYRDISWMTIVIISVTFSYMLFSPIGFIPVLGQIDDIIVLAICLKLIYADLEKYKHFKEEQKSQNNNTGN
>NZ_CP011308.1|WP_046550880.1|1004428_1005007_-|rRNA-pseudouridine-synthase
MHSTMSDSKKLLVLNKPKGYVVTRSDELGRKKVYDLLPDWTFNDGWMPIGRLDLESKGLLLFTTDGKISDALTRPGNCIKVYEIWVRGHVTDEHIAEAKRGVESKHGLLKALVVEKIGTGGAKTKLKIVIDEGKNRHIRRLFGALKDPKFGTPLKVLELKRISIGSFEPDIESGKWRYLTVEEESMLLDAFS
>NZ_CP011308.1|WP_046550881.1|1005297_1005873_+|class-I-SAM-dependent-methyltransferase
MARIDQKNFYQNNYDTYGVSAEGVAWDSLQTQRRRFSAIASCLGNVMQDTLVDAGCGFGDFYLYLREKNNLPKTYTGLDLCEPMVKEAQVRTGCKIMHRDILCQTLPVADWYVASGSMNLLTRFETRLFIQRCFDKSRKGFVFNLLEGREREGEFSYWLPHEIRELCRSLGAKVQIKEGYMEGDFTVMLGG
>NZ_CP011308.1|WP_046550882.1|1006099_1006426_+|hypothetical-protein
MKKHIKKFTVFSKNIGKGLNVEFKETIEIPSLIRRKEYKKAGAQVVDLFKMTGLTIVWIIPGGAVLTTMILKFSHKSRPSAFQSNAEEGSLGSKEPDTLNGTVESSQK

Crispr_ID: NZ_CP011308_3

• CRISPR_ID: NZ_CP011308_3
• CRISPR_location: 1441628-1441722
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP011308_3

Consensus_repeat	Method
GTGATAGTGGATTGTGATAGTGA	CRISPRCasFinder

spacers of NZ_CP011308_3

>3.1|1441651|49|NZ_CP011308|CRISPRCasFinder
CTGTGGTTGGGTTAGTGCTTCGCAGGACTTTTCATCAGCCATTGGCTGT

CRISPR arrays and Neighbor proteins around NZ_CP011308_3

CRISPR arrays

The CRISPR arrays of NZ_CP011308_3

>merge|NZ_CP011308|3|1441628-1441722|CRISPRCasFinder
GTGATAGTGGATTGTGATAGTGACTGTGGTTGGGTTAGTGCTTCGCAGGACTTTTCATCAGCCATTGGCTGTGTGATAGTGGATTGTGATAGTGA

>NZ_CP011308|3|3|1441628-1441722|CRISPRCasFinder
GTGATAGTGGATTGTGATAGTGA	CTGTGGTTGGGTTAGTGCTTCGCAGGACTTTTCATCAGCCATTGGCTGT
GTGATAGTGGATTGTGATAGTGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011308.1|WP_046551270.1|1446500_1447232_-|capsular-biosynthesis-protein	unknown	unknown	gnl|CDD|226870
NZ_CP011308.1|WP_046551275.1|1452426_1453959_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl|CDD|234854
NZ_CP011308.1|WP_046551266.1|1440731_1441382_-|hypothetical-protein	unknown	unknown	gnl|CDD|223203
NZ_CP011308.1|WP_046551259.1|1433038_1433644_-|undecaprenyl-phosphate-N,N'-diacetylbacillosamine-1-phosphate-transferase	unknown	unknown	gnl|CDD|376775
NZ_CP011308.1|WP_046551268.1|1443767_1445171_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|273648
NZ_CP011308.1|WP_169745668.1|1435944_1437012_-|O-antigen-ligase-family-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_052746128.1|1431482_1432109_-|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223943
NZ_CP011308.1|WP_046551265.1|1439541_1440735_-|phosphotransferase	unknown	unknown	gnl|CDD|270700
NZ_CP011308.1|WP_046551263.1|1437125_1438394_-|oligosaccharide-flippase-family-protein	unknown	unknown	gnl|CDD|240533
NZ_CP011308.1|WP_154806482.1|1445175_1445412_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046551274.1|1451589_1452366_+|RNA-methyltransferase	unknown	unknown	gnl|CDD|223640
NZ_CP011308.1|WP_046551258.1|1432092_1433049_-|ATP-grasp-domain-containing-protein	unknown	unknown	gnl|CDD|237195
NZ_CP011308.1|WP_046551269.1|1445706_1446465_-|polysaccharide-export-protein	unknown	unknown	gnl|CDD|224512
NZ_CP011308.1|WP_046551264.1|1438390_1439545_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340825
NZ_CP011308.1|WP_046550466.1|1442615_1443767_-|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|224014
NZ_CP011308.1|WP_046551272.1|1449942_1450317_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|133394
NZ_CP011308.1|WP_046551271.1|1447231_1449544_-|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl|CDD|182106
NZ_CP011308.1|WP_046551261.1|1434847_1435948_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP011308.1|WP_046551273.1|1450326_1451205_-|DnaJ-family-protein	unknown	unknown	gnl|CDD|237667
NZ_CP011308.1|WP_046551260.1|1433656_1434784_-|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|379721

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP011308.1|WP_046551270.1|1446500_1447232_-|capsular-biosynthesis-protein	gnl|CDD|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	7.22999e-42
NZ_CP011308.1|WP_046551275.1|1452426_1453959_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl|CDD|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP011308.1|WP_046551266.1|1440731_1441382_-|hypothetical-protein	gnl|CDD|223203	COG0125, Tmk, Thymidylate kinase [Nucleotide transport and metabolism].	9.40293e-21
NZ_CP011308.1|WP_046551259.1|1433038_1433644_-|undecaprenyl-phosphate-N,N'-diacetylbacillosamine-1-phosphate-transferase	gnl|CDD|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	1.20113e-96
NZ_CP011308.1|WP_046551268.1|1443767_1445171_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	gnl|CDD|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP011308.1|WP_046551263.1|1437125_1438394_-|oligosaccharide-flippase-family-protein	gnl|CDD|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.42047e-26
NZ_CP011308.1|WP_052746128.1|1431482_1432109_-|HAD-family-hydrolase	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	1.08341e-20
NZ_CP011308.1|WP_046551265.1|1439541_1440735_-|phosphotransferase	gnl|CDD|270700	cd05151, ChoK-like, Choline Kinase and similar proteins. This subfamily is composed of bacterial and eukaryotic choline kinases, as well as eukaryotic ethanolamine kinase. ChoK catalyzes the transfer of the gamma-phosphoryl group from ATP (or CTP) to its substrate, choline, producing phosphorylcholine (PCho), a precursor to the biosynthesis of two major membrane phospholipids, phosphatidylcholine (PC), and sphingomyelin (SM). Although choline is the preferred substrate, ChoK also shows substantial activity towards ethanolamine and its N-methylated derivatives. Bacterial ChoK is also referred to as licA protein. ETNK catalyzes the transfer of the gamma-phosphoryl group from CTP to ethanolamine (Etn), the first step in the CDP-Etn pathway for the formation of the major phospholipid, phosphatidylethanolamine (PtdEtn). Unlike ChoK, ETNK shows specific activity for its substrate and displays negligible activity towards N-methylated derivatives of Etn. ChoK plays an important role in cell signaling pathways and the regulation of cell growth. The ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	2.72387e-05
NZ_CP011308.1|WP_046551261.1|1434847_1435948_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	7.38792e-31
NZ_CP011308.1|WP_046551274.1|1451589_1452366_+|RNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	7.11059e-45
NZ_CP011308.1|WP_046551258.1|1432092_1433049_-|ATP-grasp-domain-containing-protein	gnl|CDD|237195	PRK12767, PRK12767, carbamoyl phosphate synthase-like protein; Provisional.	1.64362e-106
NZ_CP011308.1|WP_046551269.1|1445706_1446465_-|polysaccharide-export-protein	gnl|CDD|224512	COG1596, Wza, Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis].	3.40379e-25
NZ_CP011308.1|WP_046551264.1|1438390_1439545_-|glycosyltransferase-family-4-protein	gnl|CDD|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	1.34223e-68
NZ_CP011308.1|WP_046550466.1|1442615_1443767_-|GDP-mannose-4,6-dehydratase	gnl|CDD|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP011308.1|WP_046551272.1|1449942_1450317_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|133394	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator. Helix-turn-helix (HTH) transcription regulator HspR, N-terminal domain. Heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	2.97126e-39
NZ_CP011308.1|WP_046551271.1|1447231_1449544_-|polysaccharide-biosynthesis-tyrosine-autokinase	gnl|CDD|182106	PRK09841, PRK09841, tyrosine-protein kinase.	1.02581e-60
NZ_CP011308.1|WP_046551273.1|1450326_1451205_-|DnaJ-family-protein	gnl|CDD|237667	PRK14299, PRK14299, chaperone protein DnaJ; Provisional.	4.32797e-62
NZ_CP011308.1|WP_046551260.1|1433656_1434784_-|nucleotidyltransferase-family-protein	gnl|CDD|379721	pfam14907, NTP_transf_5, Uncharacterized nucleotidyltransferase. This family is likely to be an uncharacterized group of nucleotidyltransferases.	2.0154e-36

Protein sequences

>NZ_CP011308.1|WP_046551266.1|1440731_1441382_-|hypothetical-protein
MLGKLITISGLDGAGKTTQIDLMTEYLNKKNISVKYIWSRGGYTPGFLLLKDIIRKLAGKKVPSAGRTSEREKKLKNPKIAKLWLTIAIIDLFFLYAVYFRLLMLFGRTIIADRYIWDTLIDFRLNFENINVEKMFLWKVLVFCAPVPDVPLYLDIPLDISVDRLSRKDEPFPDSKETLSNRLDNYKELNEQAKWKSIDAMQPIEKVHSDIVKELI
>NZ_CP011308.1|WP_046551265.1|1439541_1440735_-|phosphotransferase
MKIELLIEREPFWDILFRTLDAYYHNIDGKKRNIQLRSKKIKDLFNRNIFLVNSKLNIIFNPHVDKNIFGQTKKEFSYHPKRLKRWMQTAYVNLATTFPFSFFFAESVLEINPLVPHAKDILILGGNNRLRIMDLKSDSMIVILKKGFSRYFFDNEVLLREKMKDMDIPKLLSCNPAHSFFSEEIISGTPINRLQDDQTAQEALEKAISNLQTLYGQTIEEIELPSYESQLHSEIDGLLDNKVFSSIRDRVLSLCDKLFSFESNRETISLAMTHGDFQAANILLDKDNIWLIDWENAKKRSVDYDALTFVLKARSIELFYDAFVMFYQQGKNKEYDLFKKSISCLDDNDVERMLRVFLVENLIFALQQNNNEMFYSFDTYLVDYLEIMEKIVKDLKL
>NZ_CP011308.1|WP_046551264.1|1438390_1439545_-|glycosyltransferase-family-4-protein
MKTFVFVNQVTGPLFIDILNDFASKENCKVILLTGEVEKASASLDPTIEVQYLIKYNRMKAVYRIYTWLMFTIQTFWKLLFLDKNSELFLVSNPPFVPILSLFFKKFFHQTFHLLIYDIYPDALVNFGYIKKDSFIYKIWAKINKKLFNEAKTVFTISENMSQTILYYAPEAKPVVVHNWVDTSFIKPMDKSENWFVDKHDLKDKFVVMYSGNLGQTHDLESLIEAANLLRDHKEIQFLIIGEGVKKASLMKMIEAYDLKNVLMLPFQAPEVIPFSMTAADIGVVTLGVGAEALSVPSKTYYMLSAGNCILAIALRNSELGNLIEKYDCGAICNPGDVAVISDFILQMKENRSEFDKKCINARNASNDFTMKNAMKFYESVNSK
>NZ_CP011308.1|WP_046551263.1|1437125_1438394_-|oligosaccharide-flippase-family-protein
MKEKNIVSFMMTAGGMVFLQAVNFLIAILLARYLSAGDFGKFQLLFTMVTTLAIIAKLGMDEGFIFFIAKLKKYNESTKLLISYILFFVTVMSIIIGLLVGSNHALINKYLISQFDFEYELKIIILYLPAFVLFTTMASLMRGLEKFNVRALLTYYLAPSLFLLLLWVYILYANSLKLTLVYDFRIYTFLILAFIGIVYIFWCLRKDEKKSLSITTIKKYHKLSFALIFITLIQYMAEQPVIDLLLLSHFMTADEVGIYAVNYRLAIVPLMIYLAFNVIYATKLSKLHTAHEYDKLHSLFKVLQKRMLYLTLLLFVILFVGYDYIILLFGQEYSSGKNVFITLLVGFSFVSMNGLNATMLIINEKKKYEFYLNLFFVLILIFGGYFIVMQFGMIGLAILNSFLLFIIVIIRIYSLKSMKVLI
>NZ_CP011308.1|WP_169745668.1|1435944_1437012_-|O-antigen-ligase-family-protein
MKQPLLAVLLLVLTIAFIRYKKKIKIKIFFLSLLFPFYYLVISILYKNTYHIQVIALYFAWSFYVFIFSNYWTINKKFLNKFMNSMIIVFFIIILFGIYAISTKGMDLAYFNNRFSFLYENPNFFAQYGQVAFYSILLLIVFDGIKKYNFFWKVLMPLIIFSIAYAAHSRNVMLAMIMFYVVYYIYNLKIKILLKSLFVISIIIFFAVVDTSFLNTASSGRLVIWSYALQDISTNIGLFFGAKDNPDLSVLVHSYNKLNEATGGPVKFHADNMFVELLVEGGIVGIFIFSLPYIYVYRKIKYMEFNQRRVLTAIWVSALAQSFFVTNFTSFFSPASLFFGSIVMLPFMFQRINSK
>NZ_CP011308.1|WP_046551261.1|1434847_1435948_-|glycosyltransferase-family-4-protein
MKKTKLLLIGSLPPPWHGQSIAFQSVVDCLEGNDMKIIESSFRSKGSLGSIARLLLYFVKVPYYFIVYRPTIVYFLCSRSKIGSLRDIYLLLFTYLSSAKFYNHLHGSDLSEFISGLPPILRKIYIKLYKHVDAHAVLIKGMESEFDFLGKPDIVKVIPNFYSNVPKVDLTVKSHQDNKIQILYLSSIMKSKGIFDLIDAVDILQEKEHNIKLVIAGGFVGDTELSLSEVEKTFYEIISDKEYIEYVGVVDAETKFNLLAQSHVFALPSYYKSEAVPLSIIEAMRMGCYIIATKYKFLPSLVKDNINGGLVGIKSPRDVADKIESIIDNRELLNKISMHNIAESKRKYSEESYHANIKNFLGITKK
>NZ_CP011308.1|WP_046551260.1|1433656_1434784_-|nucleotidyltransferase-family-protein
MCLALASNTPDEKKEKFLELYNEVDDEQLYNEAKIDEVDSHVAYLMKETGISLDEKWNASFDEVEKRITNLMEELERVAAKLDEYNIPIVALKNAGITKGIYKNVACSPMGDIDLLIETDHFHKAHEIIMEELGYTFKFRSEYEHEDIEEAFRGGGTEYYQDINGYKVWLELQWRPIAGRWIQPENEPNGNELVKRSYQAAGSKVRILAPEDNLLQVALHTTKHSYVRAPGFRLHSDVDRIVRYTDIDWDKFVKQVEELQLKTSVYFSLCFAKNLLNTPIPENVLDELKPNIIRGSLIRHFIKKADIFDQKKKKFSKIGYILFNMSLYDSLGNLFVAIVPSPQTIKDLYGVENSMLLPFFYIKRLSDLIIKRAKL
>NZ_CP011308.1|WP_046551259.1|1433038_1433644_-|undecaprenyl-phosphate-N,N'-diacetylbacillosamine-1-phosphate-transferase
MNVKRVFDVVLASVLIVLFSPIYLIVSLLIWLKMGRPIFFRQQRPGLHEKIFGIYKFRTMTNDKDENGELLPDEQRLVGIGKFIRSASLDELPQIFNVLKGDMSFVGPRPLLIQYLPLYSEEQKRRHDVKPGITGWAQVNGRNAISWEQKFEYDVWYVDHQSFWLDMKILWMTFLKVVKRSDISQEGQATMEVFKGTSDDK
>NZ_CP011308.1|WP_046551258.1|1432092_1433049_-|ATP-grasp-domain-containing-protein
MINNILITSAGRRVSLVRNFQDTLKAFNENGKVYTTDMNPVLSSACQISDGFLEVPRVTDKEYLSILKNYCIDKNISIIVPTIDTELHILADVKDEFLKDNIFIAISSKEICDTFYLKDSTEKFFVDNGFDTPRSVENIEESSYPIFAKLNNSSCSIGAQIVNSLDTAKELAQDENYVFQEFIEGDEYTVDVFIDKKGEVISVVPRQRLEVRAGEVSKAKTVKDENIIKDVKTLCSSLDGAYGCITVQLFKTDDRVVFIEINPRFGGGYPLSPLSGANFAEYLIKDYLGMDLEYDESWTDGNIMLRYDAEVIVNGNSL
>NZ_CP011308.1|WP_052746128.1|1431482_1432109_-|HAD-family-hydrolase
MVIVFDLDDTLYDEVEFVKSGFKEIAEYLGNDQYYDFMFDTFVKDGSGKVFNDLIDTFDLDISLQKLIEIYRFHQPDINLPAESQELLKFSQTYHTALISDGYYLMQQNKFKALRLENYIDYPIFTDFHHTKKPELKPFEMVMEKFKEESSFVYVSDNPKKDFIAPNRLGWKSIRYKNPVGIYKEYDSDAMYEVADRTEIMNILKEMK
>NZ_CP011308.1|WP_046550466.1|1442615_1443767_-|GDP-mannose-4,6-dehydratase
MAEQKVALITGVTGQDGSYLAEFLLKKGYIVHGIKRRASLFNTDRIDHLYQDPHVEHRNFILHYGEMTDSMNLTRIIQEVQPDEIYNLAAMSHVAVSFETPEYVANADGTGTLRILEAVRLLGLTEKTRIYQASTSELYGKVQEVPQTETTPFYPRSPYAVAKMYAYWITVNYREAYDMFACNGILFNHESPVRGETFVTRKITRAASKIALGLQDKLYLGNLDAKRDWGHAKDYVKMMWLILQADEPEDWVIATGVTTAVRDFVRMAFGYVGIELEFKGEGVDEVGIVKSIDETKAKNAGLDVQRLQELAGKAVVAVDPRYFRPTEVDLLIGDPTKAEQKLGWKREYKLEELVNDMMKSDLHLMTKDQYLKEGGYTIMNYFE
>NZ_CP011308.1|WP_046551268.1|1443767_1445171_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase
MTNIILCGGSGTRLWPLSRTLMPKQFVKLFEGESLFQKTVERNQKACDSQFIVSNTEQYFLAVDQIEEHNDDHSKLNIQHLTFLLEPVGRNTAPAIALACLALDPEETVLVTPSDHLIKDEVAYLEAVERAKALAVQGSLVTFGITPQYPETGFGYIEAEGEDVRSFREKPDAQTAQSYLDAGNYYWNSGMFCFKAGTFLDELQSYAPEIFEASVKAYGQAKKDDMIRISHEDMMAIPEDSIDYAVMEQSSRVKVVPSDIAWSDLGSFDALYEELPQDSNGNASSSLNSEIITQQASNNLILSEKLVAAIDVDDLLIVDTADALLVSQKGSSQKVKEVVKKLKERNSELPNIHVTAHRPWGTYTILDESNGYKVKRIVVKPGKRLSLQKHFHRSEHWIVVSGTATVTRGNKEYLVRANESTYIPMGEIHRLENVGKIDLVMIEAQVGEYVGEDDIVRLADDFKRMEN
>NZ_CP011308.1|WP_154806482.1|1445175_1445412_-|hypothetical-protein
MHIPIPLPILAILNSYCWNWLHWPLMILPENRNYDMLGVTMGHKMFKELGRSKYESISIDEPVLIGIKGIMEDPTWRL
>NZ_CP011308.1|WP_046551269.1|1445706_1446465_-|polysaccharide-export-protein
MIKKIILSMGVLFLLAGCGSLDSEYQLVQNEQMKTQRETAVMRGSIEYRIQPQDRLKVVFYRDPQQSVQVPIGELGQEMTTDGILVDVAGYVRLPLIGKVKVAGLSQSQAADRITQRLRKYVNAPSVYVEVLNKRVYVLGEVKKPGVVKLDREKMTLFEAIAFSGDLTDNAVRDNIIIISSDPRHGLRMRSVDLTNFKTMKYASLMLRPNDIVYVQPDGWKEFRVKSDNFTAPFETITKIAAPFATLKYLSD
>NZ_CP011308.1|WP_046551270.1|1446500_1447232_-|capsular-biosynthesis-protein
MFSFFRKKEERKPAPQLKVDLHSHLIPGIDDGSQSMEESLTLLKGMEALGYEKLITTPHIMADAYKNTPKIIKTGLEELRNAAREEGIEMEIDAAAEYYLDDGFIDLLGEEEVMAINGTYLLFETSYVSKPLRTEEMIFEITLAGYTPVMAHPERYRYIKEPLKEYGRFKELGVLFQVNLNSFGGYYGKSAKVLAEFLSRNGMIDFLGSDVHRQKHVDTLEAVLKSDAYREIFAHNEIMNDKL
>NZ_CP011308.1|WP_046551271.1|1447231_1449544_-|polysaccharide-biosynthesis-tyrosine-autokinase
MNDTQIDEDEIDLKEVFRTIYRYRYMIILFVVIFTLASAGIAYFKPNVYKASSTVEVGTEGYGSYGGGQDILSMAMSPGAENTETEMEIIKSRFLAGKAAEEVDVLHRYYTTRLFREVELYTSSPFRVGMLRGYDISFELYPVDEKRYRLVLPEYEDENKTVTVVNYDKVLPYGQEIDTPYFHLNVVKTGKMTDKKYRFVVYDPKEEGSIAQEGVSVSQLSKYSMVLQISYEDNVALRAQEFANALAKAYLQQSIEKKTKEATQKLEFIDKQLKFITENLKSSAVKLEEFKKSSSTISLSAKAETIIRQMSEKETQLSEISIEEEMLTKLYQSVKSGKNLESLALVGVDKSKSSLAGMIKELQDAIIKKKILRADYTEMHPEVVKLRKTIVQLKKVIISTIKNMEKNIKERKVLLQKSIAQSQKLLDKLPADERMFGQLQRKFSVNEKIYSYLLEKRSETAIIKAATVSKNRIIDTALYPKDPIKPKRKLIVLVGMILGLIVGIALAFLRAFLDDRIKSEEDVSRATNVPLLGMIPHIKKDAEKLTVVASPKSAVAESFRHLRTNLQFMEKEKSSHIISITSTIGGEGKSTVSMNLAAIMSMADKKTILLNMDMRKPTLHERFGLKNTKGMSTLLSKHTALSDVIQHSEYSNLDVITSGPVPPNPSELIQGELMKKVLEKLGETYDVIIMDTPPIGLVTDARTLMHLSDTSIFVLRAEYSKKGFIRGIDELYKHEEIEGLGILLNDISMDRNGYGYGYGYGYGYYEDDQK
>NZ_CP011308.1|WP_046551272.1|1449942_1450317_-|helix-turn-helix-transcriptional-regulator
MMHSYDEPVYLISVVATMLDIHPQTLRQYEREGLVEPSRTQGRMRLYSQRDIDRMKLILRLTRQMGVNLAGVDIVLQLKEQIEEMQKEIEQLRDELSKVNRNGSVHVSKALVTKNSYDIVIFED
>NZ_CP011308.1|WP_046551273.1|1450326_1451205_-|DnaJ-family-protein
MSKSLYETLGVSENASADEIKKAYRKLARKYHPDINKDESAVDKFKEINAAYEVLSDAEKKAQYDQYGDQMFGGQNFHDFARGQGQGVDLDEILRQMFGGGAAGGGGGFSGSFGGAQGGFGGFGGFGGPDLNVSARITVPFMTAIQGGKYKINVEGESFDIKIPAGIKSGETLRVRGKGKSYQGQRGDLLIKVEVAESTEYERKGSDLYKTFDVPLKEALFGGKVQVQTPEKEVSLKVPKNTRNGQKFRLKGKGVPDRKTAMRGDLYLIANVVLPDVDSLDPEVRKILEEKL
>NZ_CP011308.1|WP_046551274.1|1451589_1452366_+|RNA-methyltransferase
MNFIEVNDINLPEVQIYQRLRENAFSKDGSFIADSPKVVDLLIASGIEIKSIFATREYFESHRTFLEHYTIPIAYVAPKSVLEQIVGHRLHHNVMMHGVRPEESSIEALDDHIIMLDEISNTDNVGAIARSAAALGVGSLLVPGQGPHPYARRALRVSMGHIGKLKFRRYDNIKETIEALKKRGYRIFAAEVTQNSTPLSQVKVPSKWVLLMGHEQLGISDEILALCDEVVTIEMEEGIKSFNVAVAASIMMYQFKHA
>NZ_CP011308.1|WP_046551275.1|1452426_1453959_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MRALLSVSDKSGIVEFARGLEKLGWEIISTGGTYKALSTAGINVIEIDEVTKFPECFEGRVKTLNPYVHGGILHKRGDKAHVEQAKELGVEGIDLVCVNLYPFKETIERTDDFDEIIENIDIGGPTMVRSAAKNFNDVLIVTDVNDYEEVLGALENGRDSLEFRRGLMIKAFEHTAAYDSMIANYMNGRFNNGFGAYQFITGKKVFQTRYGENPHQDGALYEFGSFFSENFRQIKGEASFNNLTDVNGALKIAASFGDEPAVCIVKHGNPCGFAIKSTLTESYVEALKCDPVSAFGGVVAVNGIVTKEMAEKMNEIFLEVIIAADFEEDAVAVFEKKKRIKLFSQGNAKLLMSHDSHDFKHIDGGFVYQNSDCICDNEVHNAQKKSKRSASEQEMKDLEIAWKVAGLTKSNCVVYVKDSAMVAVGMGMTSRVDAAQCALKKAKEMGLDVSGAAMASEAFFPFRDSIDAAAEAGVKAIIEPGGSIRDDEVIEAANEHGISLYFTTVRHFLH

Crispr_ID: NZ_CP011308_4

• CRISPR_ID: NZ_CP011308_4
• CRISPR_location: 1693884-1693972
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP011308_4

Consensus_repeat	Method
AACGACTCTACAAAAACGATCTC	CRISPRCasFinder

spacers of NZ_CP011308_4

>4.1|1693907|43|NZ_CP011308|CRISPRCasFinder
CAACGATTCAAGAGATTCTGTAAAAGACGTTTCCGACAATGCG

CRISPR arrays and Neighbor proteins around NZ_CP011308_4

CRISPR arrays

The CRISPR arrays of NZ_CP011308_4

>merge|NZ_CP011308|4|1693884-1693972|CRISPRCasFinder
AACGACTCTACAAAAACGATCTCCAACGATTCAAGAGATTCTGTAAAAGACGTTTCCGACAATGCGAACGACTCTACAAAAACGATCTC

>NZ_CP011308|4|4|1693884-1693972|CRISPRCasFinder
AACGACTCTACAAAAACGATCTC	CAACGATTCAAGAGATTCTGTAAAAGACGTTTCCGACAATGCG
AACGACTCTACAAAAACGATCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011308.1|WP_046551470.1|1692325_1692748_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046551465.1|1685747_1689314_-|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl|CDD|235554
NZ_CP011308.1|WP_046551464.1|1684580_1685630_-|hypothetical-protein	unknown	unknown	gnl|CDD|235505
NZ_CP011308.1|WP_052746158.1|1697048_1698773_-|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NZ_CP011308.1|WP_046551477.1|1706342_1707626_-|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|237003
NZ_CP011308.1|WP_046551467.1|1689833_1690394_-|DJ-1/PfpI-family-protein	unknown	unknown	gnl|CDD|153229
NZ_CP011308.1|WP_046551468.1|1690395_1691349_-|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl|CDD|379355
NZ_CP011308.1|WP_046551462.1|1680996_1681959_-|malate-dehydrogenase	unknown	unknown	gnl|CDD|133424
NZ_CP011308.1|WP_046551463.1|1682239_1684423_-|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl|CDD|377178
NZ_CP011308.1|WP_046551469.1|1691427_1692228_-|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_CP011308.1|WP_052746157.1|1694169_1696257_+|hypothetical-protein	unknown	unknown	gnl|CDD|275319
NZ_CP011308.1|WP_052746159.1|1701198_1702617_-|TolC-family-protein	unknown	unknown	gnl|CDD|224455
NZ_CP011308.1|WP_046551478.1|1707636_1708470_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	unknown	unknown	gnl|CDD|260116
NZ_CP011308.1|WP_046551466.1|1689442_1689733_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046551474.1|1700407_1701202_-|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|379862
NZ_CP011308.1|WP_046551476.1|1704497_1706156_-|30S-ribosomal-protein-S1	unknown	unknown	gnl|CDD|235775
NZ_CP011308.1|WP_046551475.1|1702823_1704413_-|phosphoglycerate-dehydrogenase	unknown	unknown	gnl|CDD|237436
NZ_CP011308.1|WP_046551472.1|1696371_1696938_-|elongation-factor-P	unknown	unknown	gnl|CDD|234788
NZ_CP011308.1|WP_046551461.1|1680047_1680992_-|malate-dehydrogenase	unknown	unknown	gnl|CDD|133424
NZ_CP011308.1|WP_046551473.1|1698772_1700401_-|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP011308.1|WP_046551467.1|1689833_1690394_-|DJ-1/PfpI-family-protein	gnl|CDD|153229	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. DJ-1 is involved in multiple physiological processes including cancer, Parkinson's disease and male fertility. It is unclear how DJ-1 functions in these. DJ-1 has been shown to possess chaperone activity. DJ-1 is preferentially expressed in the testis and moderately in other tissues; it is induced together with genes involved in oxidative stress response. The Drosophila homologue (DJ-1A) plays an essential role in oxidative stress response and neuronal maintenance. Inhibition of DJ-1A function through RNAi, results in the cellular accumulation of reactive oxygen species, organismal hypersensitivity to oxidative stress, and dysfunction and degeneration of dopaminergic and photoreceptor neurons. DJ-1 has lacks enzymatic activity and the catalytic triad of typical GATase1 domains, however it does contain the highly conserved cysteine located at the nucelophile elbow region typical of these domains. This cysteine been proposed to be a site of regulation of DJ-1 activity by oxidation. DJ-1 is a dimeric enzyme.	1.5882e-60
NZ_CP011308.1|WP_046551465.1|1685747_1689314_-|DNA-polymerase-III-subunit-alpha	gnl|CDD|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NZ_CP011308.1|WP_046551464.1|1684580_1685630_-|hypothetical-protein	gnl|CDD|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0.00344071
NZ_CP011308.1|WP_052746158.1|1697048_1698773_-|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	4.52186e-58
NZ_CP011308.1|WP_046551477.1|1706342_1707626_-|3-phosphoshikimate-1-carboxyvinyltransferase	gnl|CDD|237003	PRK11860, PRK11860, bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase.	0
NZ_CP011308.1|WP_046551473.1|1698772_1700401_-|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	7.80381e-98
NZ_CP011308.1|WP_046551468.1|1690395_1691349_-|NAD(P)-binding-domain-containing-protein	gnl|CDD|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	4.96714e-62
NZ_CP011308.1|WP_046551462.1|1680996_1681959_-|malate-dehydrogenase	gnl|CDD|133424	cd01339, LDH-like_MDH, L-lactate dehydrogenase-like malate dehydrogenase proteins. Members of this subfamily have an LDH-like structure and an MDH enzymatic activity. Some members, like MJ0490 from Methanococcus jannaschii, exhibit both MDH and LDH activities. Tetrameric MDHs, including those from phototrophic bacteria, are more similar to LDHs than to other MDHs. LDH catalyzes the last step of glycolysis in which pyruvate is converted to L-lactate. MDH is one of the key enzymes in the citric acid cycle, facilitating both the conversion of malate to oxaloacetate and replenishing levels of oxalacetate by reductive carboxylation of pyruvate. The LDH-like MDHs are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	1.1777e-165
NZ_CP011308.1|WP_046551463.1|1682239_1684423_-|NADP-dependent-isocitrate-dehydrogenase	gnl|CDD|377178	pfam03971, IDH, Monomeric isocitrate dehydrogenase. NADP(+)-dependent isocitrate dehydrogenase (ICD) is an important enzyme of the intermediary metabolism, as it controls the carbon flux within the citric acid cycle and supplies the cell with 2-oxoglutarate EC:1.1.1.42 and NADPH for biosynthetic purposes.	0
NZ_CP011308.1|WP_052746157.1|1694169_1696257_+|hypothetical-protein	gnl|CDD|275319	TIGR04526, predic_Ig_block, putative immunoglobulin-blocking virulence protein. Members of this family are putative virulence proteins of Mycoplasma and Ureaplasma species. Members share a region of sequence similarity (see TIGR04524) with protein M, a Mycoplasma genitalium protein that binds a conserved light chain region of IgG and blocks its protective function of antigen-specific binding. The seed alignment for this model includes an N-terminal signal-anchor domain and a proline-rich linker domain, and a C-terminal extension, in addition to the protein M-like domain recognized by TIGR04524. [Cellular processes, Pathogenesis].	0.00596828
NZ_CP011308.1|WP_052746159.1|1701198_1702617_-|TolC-family-protein	gnl|CDD|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.51479e-33
NZ_CP011308.1|WP_046551478.1|1707636_1708470_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	gnl|CDD|260116	cd13944, lytB_ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. The 4-hydroxy-3-methylbut-2-enyl diphosphate (HMBPP) reductase (called lytB or ispH) is the terminal enzyme of the mevalonate-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway, one of the two metabolic routes for isoprenoid biosynthesis. The MEP pathway is essential in many eubacteria, plants, and the malaria parasite. LytB converts HMBPP into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).	1.17757e-127
NZ_CP011308.1|WP_046551469.1|1691427_1692228_-|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	6.72259e-25
NZ_CP011308.1|WP_046551474.1|1700407_1701202_-|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|379862	pfam16576, HlyD_D23, Barrel-sandwich domain of CusB or HlyD membrane-fusion. HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.	9.46604e-34
NZ_CP011308.1|WP_046551476.1|1704497_1706156_-|30S-ribosomal-protein-S1	gnl|CDD|235775	PRK06299, rpsA, 30S ribosomal protein S1; Reviewed.	0
NZ_CP011308.1|WP_046551475.1|1702823_1704413_-|phosphoglycerate-dehydrogenase	gnl|CDD|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0
NZ_CP011308.1|WP_046551472.1|1696371_1696938_-|elongation-factor-P	gnl|CDD|234788	PRK00529, PRK00529, elongation factor P; Validated.	5.18638e-97
NZ_CP011308.1|WP_046551461.1|1680047_1680992_-|malate-dehydrogenase	gnl|CDD|133424	cd01339, LDH-like_MDH, L-lactate dehydrogenase-like malate dehydrogenase proteins. Members of this subfamily have an LDH-like structure and an MDH enzymatic activity. Some members, like MJ0490 from Methanococcus jannaschii, exhibit both MDH and LDH activities. Tetrameric MDHs, including those from phototrophic bacteria, are more similar to LDHs than to other MDHs. LDH catalyzes the last step of glycolysis in which pyruvate is converted to L-lactate. MDH is one of the key enzymes in the citric acid cycle, facilitating both the conversion of malate to oxaloacetate and replenishing levels of oxalacetate by reductive carboxylation of pyruvate. The LDH-like MDHs are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	5.36976e-146

Protein sequences

>NZ_CP011308.1|WP_046551470.1|1692325_1692748_-|hypothetical-protein
MVELLRRFTLLTAVTTAFAMAEGYTQADRIADMQKMAQAMQDIQSGFFYNNVDIIKAGTKVLKETITNVRPIDSEVNNKDIYEKWLNNDLKMTRKIQKKIKNKANDVEERFSDGDAVQALQAYSKISGQCMKCHVRLRKW
>NZ_CP011308.1|WP_046551469.1|1691427_1692228_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MLRLQKITLFLLLLGSFVHAGSISLTGTVVSDGQKMIGSRYMGYVKKVYVKLGDKVKREDDLYEMESAEFDIMKTQANLMLEQSQIALEYWKDRLRVINKKKENVKKKYGMTGFGMDDLEGQIETVKAMLESTKIMVKHAAEQVKQMAVVFNYLKMKAPADGVVVQKNIKVGDMLMPGMLAIMIVDTEHLEIDVSLSEGIINRVHEGQKLAVVIPSIEYRTIGKIKAIIPDANPMTHKIKMRVSFDKGDNNIFPGMYAKVIIPDKK
>NZ_CP011308.1|WP_046551468.1|1690395_1691349_-|NAD(P)-binding-domain-containing-protein
MEKIYDLIIIGGGPGGIGSAVEAKVLGLEKVLMIEKTDNHSHTIRKFYKDMKRVDKDWQGQAVDMEGNVEFTDGTKESTLDFFDSLLDDEKIDTRFNCAVEKVEKKDGVFHVVSGCGVDRAKNVIVAIGRMGKPNKPSYKIPPSLRSQINFNLDKCSNGEHILVVGGGDSAVEYACELSATNEVTLNYRREDLTRPNPTNQEMIAEYCDNEAVRLKLGVDIEGLESEHGQVKVNFTDGSELFDRVIYAIGGTTPKDFLKSCGITLDETGEPVFDDNYESEVPGLYIAGDIVFNSGGSIAIALNHGYRIVNHILSKEN
>NZ_CP011308.1|WP_046551467.1|1689833_1690394_-|DJ-1/PfpI-family-protein
MASVLIPLAKGFEELEAVALIDVMRRGGIEVRVAYLEDEMQSDLVLGANGITIKADTSIKNVISDDFDMMVLPGGWGGTYALAENARVQELLREFKEKKIVGAMCAAPFALKQAGVLGERYTAYPGAVEEIDHPGYVADEKVVEDGNVMTSQGPGTAVCFGLAIVKRLVGEESMQAVKEGMLLGYC
>NZ_CP011308.1|WP_046551466.1|1689442_1689733_-|hypothetical-protein
MKLSIIAVLLSFTIVMGFGSEHNTTKENNSTIDNNKTKEAVKKAMELEKKYAKEQRFYQGSEYDLKSKEFDPETLKKVPAIEPDYDFDMDEGVYSD
>NZ_CP011308.1|WP_046551465.1|1685747_1689314_-|DNA-polymerase-III-subunit-alpha
MSEEPKSKPQFTHLHLHTEYSLLDGANKIKALAKKVKELGMTSVAMTDHGNMFGTIDFYNTMRKEGIKPIIGMEAYVHNQPELGDKSVRQRFHLCLYAKNEAGYKNLMFLSSKAYIEGFYYYPRINWDLLKDHAEGLVCSSACLQGEVNWHLNLSERNLKFGAKGYEEAKRIALKYKEVFGDDFYLELMRHGIGDQHRIDKQILQLSQETGIKIVATNDTHYTNPQDADAHEAFMCIAMNKLYDDPNRLRHSVHEFYVKSPEQMAELFADIPEALEATQEIADKCNLEIKLGNPTPPNFKFAREKADEIGLELPEPEVEYSLENDKTLFIEESKRGLAERLKIVPEEKHQEYWHRLQVEIDIINNMKFPGYMLIVWEFVDAAKRMGIPVGPGRGSAAGSLVAYALRITDIDPMPYGLLFERFLNPERISMPDIDMDFCQARRQEILDYVVEKYGRVNVAQIITFGKLLAKGVIRDVARVLDMPYSKADAMAKLIPDELGIDLKASYEKEPKIKELLESDPQAKRTWEYALALEGLNRNAGTHAAGVVISNEALWQKTPLFKPSGLDTLATQYSGKYVEDVDLIKFDFLGLKTLTVIEEALQLVEKRHGKRINFVEENIEDPKVYDYISTGETLGLFQIESAGMQDLAKKLKPSGFEDIIAMLALYRPGPMESGMLDDFVERKHGRAEITYAFPELEPILKPTYGVIVYQEQVMQIVQTIGGFSLGGADLVRRAMGKKIKEEMDKLKDEFADGAAKKGFDRAKAADLFDLIVKFAGYGFNKSHSAAYAMVTFYTSYLKYYYPTEFMAAILTLEKNNTDKVVKYVDELKQMGIKLLPPDINRSGLVFEATNIDGDEVVMFGMGAVKGAGDIAINSMLKAREEGKFSDFSDFVSRIDSSKVNKKVIESLIKAGALDSFGYSRKAMLSQIEDIIDTAKKAGEAKKMAVGSLFGEGQEMTSVTLELSHMEEFEPMEILEMEKESLGFYVSGHPLDKYRETLEGINYTLSSEIDDLADGSQALFIGKIESITEKISKKGNKFGIANIMDLHGNIELMLFENRLKELDEGFDTTKPIAFKVKISKDGDFTRMNIIKIESLKDAKKEKVKVKKEEKHTLEPEQPPLILALNLMPDAKTVEDLMCLVERYPGKRPLELRIKSKLADVIIESKWKVSEMILGEAKELGAYLEENLSVE
>NZ_CP011308.1|WP_046551464.1|1684580_1685630_-|hypothetical-protein
MNLYKVAIMFALFFTYLQADVSLGQTKAESTADPGLGFKTQDPKVSKIISLEEENERLKEKVKELEAQIETLKEDDVTVEVKSEPSVKVEVPPKVFKGAKLVIGGKVPKKLSTYYAARLQNIDDLKQKLEANGFEVLAVTPILKGKTVLSITNDELLQTNTWMAALHLLVNEGNEIRVQNPSYFGAAYLQDKYKYGQFTKTLKALQAVLGDMYEVDEKYALDDLPKYQFMFGMPYLNDTIKVGEGDDLLAKVAGGNGNKYVAYTLKLPNGNVLVGHKLRNITNKFLQKIEAERDANILPYESMIKGKKAVMLDPKFYLALSIPQLSMSEFMKIASAPGEIEKDVKRAYQ
>NZ_CP011308.1|WP_046551463.1|1682239_1684423_-|NADP-dependent-isocitrate-dehydrogenase
MSKPTIIWSKIDEAPALATYSLLPIVSKFTNAAGVDVKTSDISLAGRVLAAMGLAEDELSKLGELVHKPEANIIKLPNISASIGQLKECIAELQSQGFDIPDFPENPETEEEKAVRAKYNPCLGSAVNPVLREGNSDRRAAAAVKKYAQQHPHRLKPFAENSKAYVAHMEGNGDFYGNEKSVTMDKAQTVKILLNGKELKTIDALESEILDATFMSAKALRAFIKKTIDDAKANGVLWSIHLKATMMKISDPIMFGHAFEVFFQEVFDKYADVFKELEVNPNLGMSDLEKKIAGHAKEAEIKAAFQAVVDADAPKIAMVDSDKGQTNFNASNDVIIDASMPVVVREGGKQWDRNGDAVECVAVIPDSTYAMFHQEMVADCVKNGQFDVTTMGNVANVGLMAQKAEEYGSHPTTFEIAEAGTVDVVNENGDVLMSHEVEAGDIWRMSRAKDIPIKDWVRLAVERARLTGNPTVFWLDENRAHDAEMIKKVNQYLKEHDTTGLDIKIMDVAAATRYTNERVRAGKDTISVTGNVLRDHLTDMYPILELGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVDQFLAEGHLRWDSLGEFLALAESLRMEYQKSEDSKIGALTEALDKANQGYLDNDKAPSRKVGEADNKASHYYVALYWAEALETQTADAELAEKFAPVADALRKNEEKIIAELLAAEGSAKDIGGYYHPNDSKAEAAMRPSETLNSIIDAI
>NZ_CP011308.1|WP_046551462.1|1680996_1681959_-|malate-dehydrogenase
MAKGKKVTVIGTGNFGSTVAFILAMNGSCHHVMLRGRNYDIAKGKALDMSQAANAARQHTIVKAAKGPEDMEGSDVVIITAGAPRTPGMSRDDLLFKNADIVKCYAREIKEYAPDAIVIVVSNPLDVMTYVALKETGFPRQRVLGMAGILDAARMAHFIYEKLEYGAGQIRATVMGGHGDTMVPLPKFTTVAGVPIEDLLDSEEIGEIVRKTRNGGAEIVNLLGNGSAYYAPAKSTTVMVEAILKDTNQIHSCAIMLKNDYGYSDIVSGVPVMIGAGGAEKVINMALKPLQQTRFKNSVASVQEMVDTLYKANFFDDDKK
>NZ_CP011308.1|WP_046551461.1|1680047_1680992_-|malate-dehydrogenase
MHRRKVGIIGTGAVGATAAYSLCMMGTCNEIVLFDIAEGVAKGKAIDIAQSSHYAPNSTIVTAAESPADVNDCDIVVITAGVPRKGDMTREDLLMINAKIMKTVVEDVKTYSPDAVIICVSNPLDVMTYVIQKMTGWERNRIIGMAGALDGARMAYQIYNKLGYGAGQIGTLVIGDHGQNMIPLPQKVQVGDVPVNELLSKAEMEEIIERTRTGGAEIVKYLGTSGYYAPGRAIAYMVEALLNDSRIVVSSSVLLDGEYGYSDVTAGVPVVLGKNGVEKIIEIDLDSETIEKFKISVDSINENIAILKQNKFFD
>NZ_CP011308.1|WP_052746157.1|1694169_1696257_+|hypothetical-protein
MSLFKKFFILSLLFIIPLSLFSANTKNDDSLAVIYTIKGDAEKKYNAMMEEKLKTIGFNLTDPHKRVNDQYKKKYGSTVLDVLSFMPVVNDKMMLPLLNIDPRISGFGPFNMLIAKKLDEDFTQVGHLSPKVMLDILGIKDQKIRDTFTASFASLDAMVEKELGGKKSYLPLKKLPKQTMLTYEYTFEPVDDIEDFMDEFQGKFEDAFIKKEYLIAGYHNFMESTPDATEVLKDYDAFWTYSLCHLEFSYNMFDTENAKPLAGLFAPCTMYMFIPKGSNKLIVGMYRLHNWTDSLGITDEKRVKLVEKLDREIPELLTSLGMKATPNVNPLIGSPKPIAKPAVTQKRKVPTVPAKPSAKKEETKAKAVATTETKKTINIPTSNKTVEITLPIPPKPVKPVKIKTFHTQQKILDRSIKFSKRMPPNYIPPEQRIAKGKAKNTATDIGEVVHGRVPAYIRGKYIDVKEAEKRLKKAGFTILGETTLDKKGNLVSIVFTDKGLRKMAGKKNRGFAASLRLLVDKKDNHISITNPIYMAKAFMQDQYDDKAAKATLKKITDNFENLLNSKDKLKFQLLPNYQFMHGMPKYQDMVVVARGDNLLSKIKNNKKVLFVQKLDNGATLIGVALGRRTGKFIGRIGTNNAALLPYPVLIENGEAKIMEPKYYISVMYPLLQMSEFMTIATVPGAIIRDCGKVFK
>NZ_CP011308.1|WP_046551472.1|1696371_1696938_-|elongation-factor-P
MATIGMGDIKKGVRLELDGNPYKVTEFQHVKPGKGAAFVRVKIKNLKTGKVIEKTVHAGDKFEVPELEQKTMQYLYDDGEMLQFMDTTTFDQIGLTHEQVGKETFEFMIDGMEADILFHNGEAISVEIPQTVVLKIVETPPNFKGDSQGGKKPATLESGAVVQVPFHVLEGEMIKVDTVEGKYLEKAK
>NZ_CP011308.1|WP_052746158.1|1697048_1698773_-|efflux-RND-transporter-permease-subunit
MKGLEKFIYGILSSKSKKMLVIVLTAAAFFLSLMMFPTKMVLAKMLPGKSDNTFSVYVDTPTGSSIEQTDKVNQCVIDILKDEKEIMNLELFRGQGIPLDYAGLVKGAAMKSTENVSEISVNLTDKHTRAEPSFLMTQRLRPIVKKKCLPLVKGTNIKFVEQPAGPPTLASIVLEVHGENLKKVRDISVRVANIFAKTEGLVDIDVMMDDIFDKFELIPDKEKVARSGLSVEQVNNILYLAFEGMVIAHKNSKDVPDQIPIFLILQKESKTLNGRNENELRSKLSSLNLMNMKGMMVPLSEVVTIRKVKSSPMIMHKDLSRMVNVVAETDMVSQVYPLLDAREKMIEAFSKDYEIEKAGFTTYMFDLYLTDKKTGEKFLLRWDGEMKVTLDTFRDLGGAFIAALVLIFLLLVIYYKSFAISGIILLGSFLSLIGVIVGHWVANFFTSETFFLTATSLIGFIALMGISSRNSLLLIDFAKSLMEYHGMDKKEAIATATATRAKPIALTAVAIILGSALLASDPVFGGLGVALISGTVAAVFVSLIFVPVLMHNSKAMDFHLDEHGKRKDSISITK
>NZ_CP011308.1|WP_046551473.1|1698772_1700401_-|efflux-RND-transporter-permease-subunit
MAEKNEYQVTDYAGKLAKGFLRNPLTAVLGVFLLLMGYLALNIMPREEDPQIAISGGGVVVAMPGATPREIENIIINPLERKLREVKGIEHIYGQAFNNYGVVSVMYYIGENREDSNLKLYDKVMQNMDLMPKGVMQPLIKPFDIDIDIPIVTVAFYPKKGSNVDDVKLFEMVRKIQQKINAVDNVAKTTLKGARKAQYNIEVDMSKLSAYHLSMGQIMKAVQSVAVDVPDVKGRTKNNELVIFGVKNAIENVQDVGSVIVAQYMGSPIYLRDVAKVTEGMDIQNFKTATVRFKEDANATKLGEERNQVTLTVAKLAGTNAVFVAEDVLEVLKEHEKEFAKEGIGYIITRNYGERANEAVNELMNHLIITIVIIALMLVFALGWKESLIVTFTVPAILAITLFVAYLSGQTINRITLFAFLLSLGLLVDAAIIVIENIHRHLHAHDVDEKEMDQLLIEATDEIGAPTNVATLAIILTMVPMAFVGGMMGSFMKPIPYNVPVALIASLFVAYIFTPYLSLKLLKKPVHKHHHHKKDKKNKEVK
>NZ_CP011308.1|WP_046551474.1|1700407_1701202_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MKKIITLMAAALLTTLSAVEIDLSGSVVSDNQKMMTSRYMGYIKNMAVSEGDIVKKGQLLYEIDSKEIEAAERQVDLAISQARLALQMNKNQYNNVILNLARHKRLYEKKMVSKYELETLQLAAKNLKDMVTISQEQVNQALAKKEEVLNQYNYLKITAPNDGVIVAKKINEGEMAIPGMPAVVLTDLSRLKIVAEISETQLPHISLGKKVEVEIPSLALKTTGKISSIIPSSNPMTHKFKIKIEFDHKGKSVYPGMYAKIIIR
>NZ_CP011308.1|WP_052746159.1|1701198_1702617_-|TolC-family-protein
MMMKRVILLLSLSLPLVAGVKNLPLREALDMVKHDNLEVKVARFNEQMQAMEVKVAEGMNYGSLDVTLSGMRSNDALNVFGFKLMDREATFGDFGFSQFLEPIGNALMAANNGQLTPQMLQGMSSILEIQPHDLNYPGARNNYQTKLSYMLPIYTGGKLTEYKHIMESMYRMSKYDTQKLLNVKIYEVKKAFYDISLVERYITNLSKIRKNINTLEDVIRNMQKEGYAKEMDLLEVQARKAEADSMYNQAKLNRDLAYQFLSFLLNRDISSIHKVSARAPMPHVDKHTLELNNIDIQKAKLGLQISEMAVKVEKSSFLPTVGGFAEYGSADNTLFNDFTGKDSYTFGVQAKWNIFNGGQDDARLEKAKLKRLQVRDQVELAKKGIVLKAKKLKTEILSADADIKSYKKQLQFAKRVYENYRTRYEEGLASITDVLIQQSKQLESLLKLLTVVNKRNTKIFELESIINKGGDV
>NZ_CP011308.1|WP_046551475.1|1702823_1704413_-|phosphoglycerate-dehydrogenase
MSKKTIVVCDHIHQSGLDILANDSEIELINAADEPKDKLIAEIIPLADVAITRSSTDVDAAFLESAKKITAIVRAGVGVDNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYAHNNLKLDRVWRRQDWYGTELKDKKLGIIGFGNIGSRVGKRAKAFEMDVLAYDPYIDPSKATDLDIGYTKNFEDILACDIITIHTPKTEETIGMISKDEIAKMKDGVILINCARGGLYNEEALLEGLKSGKIAMAGIDVFNKEPATDHPLLDLDNVTVTPHLGANTKESQRNIAIQAAENAIAAAKGIAYPNALNLPIKENELPDFVRPYLELIQKMGHLSSQVTKSAVKSIKVTAKGPVSDYLASMQTFATVGVLTESLADQVNYVNAEFVAKERGIELANEVLPNTSGFTNKVKIKLTTADSTIMIAGTVFDDTVQRIIEIDDYILDVEPKGTMIFFRNTDTPGVIGDVGRILAENGLNISDFRLGRDKKQQALAVVRVDGQVSKDVLDALSALEACISVSHATL
>NZ_CP011308.1|WP_046551476.1|1704497_1706156_-|30S-ribosomal-protein-S1
MKFEDIEIEDVDFEAMLEESFKKSESRSDLVTGTVVKIDEKDNLAVVDIGGGRDANLALDEIKDEEGNILFNVGDNIDVLNMGRGRISYKAALGRAALNEFISEYDEEQEYIIEGVVTKKNKGGYVVEVDGLEFFMPRTLSYLSSKPGFEAIGKKVKAVIVKVDKDKGSVVVSRKELIERDKAKTDEIVGELLENKEPVVGTIKKITSYGMFVDVGGMDGLVHYSQISHKGPVNPSKYFQEGDEVNVIALEYDKKKRHLSLSIKDANPDPWADIDSIIGVGDTVTATVSNIEPYGVFVDLGEDLEAFLHVSEISWDKNVKHPKDYLTNGEEINVEVIEVDKEGRRLRVSLKSLLPKPMDAFVQQYRVGDVVKGKVTSITDFGAFVKVGSVEGLLHNQEISWDKSKNAKSELAVGDEVEVKIIKIDKDAGKISLSKKALEDSPIKAFAQTHKNGSIVTGTVKDKKDFGVFIALDDNVDALIRTEDLHPLKFDEIEKGQEIKGVISFIDENNDRIRVSVKRLERQEEREAMEQLNLNQDDSMTLGDAFGDKFKK
>NZ_CP011308.1|WP_046551477.1|1706342_1707626_-|3-phosphoshikimate-1-carboxyvinyltransferase
MNSITLKPIRYIEGEVNLPGSKSLSNRALLIAALAEGTTRITNLLESDDTRHMLNALKLLGVEYTLSEDRTECTVVGNGGPFHTKKPLELFLGNAGTAMRPLCAALTLGSGTYVLTGELRMKERPIGHLVDALREAGAKITYLENEGYPPLKIEADGLKGGEVRIDGSISSQFLTALLMAAPMARGDMQIDIVGELVSKPYIDITLHIMKQFGVEVRNENYERFFIKGGQTYQALETFMVEGDASSASYFLAAAAIKGGTVKVTGIGKASIQGDVAFADVLEKMGAKVEWGDDYVSVSRGELNAVNMDFNHIPDAAMTIATTALFAEGTTTLRNIYNWRVKETDRLHAMATELRKVGAEVEEGEDYLTITPPVQLKHASIDTYDDHRMAMCFSLLALDPVSVTINEPECTAKTFPTYFEVFESISRY
>NZ_CP011308.1|WP_046551478.1|1707636_1708470_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase
MKIQLASSYGFCFGVKRAIKIAEEHQGSKTYGPLIHNKDEINRLKEGFDIGLAEKLDDVTPEDSVVIRTHGIPKDELSQLKAQENPIIDATCPYVTTPQNIVANMSEKGYSIVIFGDKEHPEIKGVVSYAKDLRNAFIVRHEDELEGLPILSKVAVVAQTTRKPEDFLKIVNALILNHKEVRVFNTICNATFENQDAAAELARDADVMIVIGGKHSSNTKQLHSICKSYCDDSYLVENESELDPQWFGGKKLCGISAGASTPDWIVQNVIDKIEALK

Crispr_ID: NZ_CP011308_5

• CRISPR_ID: NZ_CP011308_5
• CRISPR_location: 1813989-1814122
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP011308_5

Consensus_repeat	Method
GGTGAATAAGATGTGAACAACTCATATTAATTAATGCAACGCG	CRISPRCasFinder

spacers of NZ_CP011308_5

>5.1|1814032|48|NZ_CP011308|CRISPRCasFinder
GTGATACGGGACGTAGATAAATTATTCGACTTTTTTATCTTTTCACAT

CRISPR arrays and Neighbor proteins around NZ_CP011308_5

CRISPR arrays

The CRISPR arrays of NZ_CP011308_5

>merge|NZ_CP011308|5|1813989-1814122|CRISPRCasFinder
GGTGAATAAGATGTGAACAACTCATATTAATTAATGCAACGCGGTGATACGGGACGTAGATAAATTATTCGACTTTTTTATCTTTTCACATGGTGAATAAGATGTGAACAACTCATATTAATTAATGCAACGCG

>NZ_CP011308|5|5|1813989-1814122|CRISPRCasFinder
GGTGAATAAGATGTGAACAACTCATATTAATTAATGCAACGCG	GTGATACGGGACGTAGATAAATTATTCGACTTTTTTATCTTTTCACAT
GGTGAATAAGATGTGAACAACTCATATTAATTAATGCAACGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011308.1|WP_046551543.1|1808275_1809682_+|anthranilate-synthase-component-I-family-protein	unknown	unknown	gnl|CDD|223225
NZ_CP011308.1|WP_052746168.1|1807504_1808272_+|SPOR-domain-containing-protein	unknown	unknown	gnl|CDD|225629
NZ_CP011308.1|WP_046552139.1|1814148_1814856_-|carboxy-S-adenosyl-L-methionine-synthase-CmoA	unknown	unknown	gnl|CDD|273244
NZ_CP011308.1|WP_046551550.1|1818387_1820334_-|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NZ_CP011308.1|WP_046551549.1|1817677_1818391_-|TlyA-family-RNA-methyltransferase	unknown	unknown	gnl|CDD|224110
NZ_CP011308.1|WP_046551553.1|1821967_1822585_-|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl|CDD|236274
NZ_CP011308.1|WP_046551540.1|1799799_1800675_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP011308.1|WP_046551555.1|1824399_1824873_-|RNA-pyrophosphohydrolase	unknown	unknown	gnl|CDD|234820
NZ_CP011308.1|WP_046551544.1|1809685_1810483_+|shikimate-dehydrogenase	unknown	unknown	gnl|CDD|234703
NZ_CP011308.1|WP_046551546.1|1811210_1812401_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP011308.1|WP_179944233.1|1812509_1813859_-|3-deoxy-7-phosphoheptulonate-synthase-class-II	unknown	unknown	gnl|CDD|366662
NZ_CP011308.1|WP_046551552.1|1820601_1821741_-|dihydropteroate-synthase	unknown	unknown	gnl|CDD|238380
NZ_CP011308.1|WP_046551541.1|1800671_1802177_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|227274
NZ_CP011308.1|WP_046551542.1|1804264_1807357_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NZ_CP011308.1|WP_084722063.1|1822587_1823133_-|HobA-family-DNA-replication-regulator	unknown	unknown	gnl|CDD|338263
NZ_CP011308.1|WP_052746169.1|1816838_1817645_-|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl|CDD|235536
NZ_CP011308.1|WP_046551548.1|1815018_1816842_+|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NZ_CP011308.1|WP_046551545.1|1810564_1811218_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP011308.1|WP_154806494.1|1802517_1803828_-|IS5-family-transposase	unknown	unknown	gnl|CDD|377531
NZ_CP011308.1|WP_046551554.1|1823139_1824345_-|aspartate-kinase	unknown	unknown	gnl|CDD|235843

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP011308.1|WP_046551543.1|1808275_1809682_+|anthranilate-synthase-component-I-family-protein	gnl|CDD|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	8.0834e-158
NZ_CP011308.1|WP_052746168.1|1807504_1808272_+|SPOR-domain-containing-protein	gnl|CDD|225629	COG3087, FtsN, Cell division protein [Cell division and chromosome partitioning].	3.82805e-08
NZ_CP011308.1|WP_046552139.1|1814148_1814856_-|carboxy-S-adenosyl-L-methionine-synthase-CmoA	gnl|CDD|273244	TIGR00740, tRNA_cmo5U34-methyltransferase, tRNA (cmo5U34)-methyltransferase. This tRNA methyltransferase is involved, together with cmoB, in preparing the uridine-5-oxyacetic acid (cmo5U) at position 34. [Unknown function, Enzymes of unknown specificity].	1.85185e-51
NZ_CP011308.1|WP_046551550.1|1818387_1820334_-|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP011308.1|WP_046551549.1|1817677_1818391_-|TlyA-family-RNA-methyltransferase	gnl|CDD|224110	COG1189, COG1189, Predicted rRNA methylase [Translation, ribosomal structure and biogenesis].	6.87238e-79
NZ_CP011308.1|WP_046551553.1|1821967_1822585_-|DNA-polymerase-III-subunit-delta'	gnl|CDD|236274	PRK08485, PRK08485, DNA polymerase III subunit delta'; Validated.	4.39752e-39
NZ_CP011308.1|WP_046551555.1|1824399_1824873_-|RNA-pyrophosphohydrolase	gnl|CDD|234820	PRK00714, PRK00714, RNA pyrophosphohydrolase; Reviewed.	9.29281e-74
NZ_CP011308.1|WP_046551544.1|1809685_1810483_+|shikimate-dehydrogenase	gnl|CDD|234703	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed.	4.8168e-104
NZ_CP011308.1|WP_046551546.1|1811210_1812401_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.82894e-24
NZ_CP011308.1|WP_179944233.1|1812509_1813859_-|3-deoxy-7-phosphoheptulonate-synthase-class-II	gnl|CDD|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NZ_CP011308.1|WP_046551552.1|1820601_1821741_-|dihydropteroate-synthase	gnl|CDD|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	1.62182e-114
NZ_CP011308.1|WP_046551541.1|1800671_1802177_-|AAA-family-ATPase	gnl|CDD|227274	COG4938, COG4938, Uncharacterized conserved protein [Function unknown].	2.2735e-21
NZ_CP011308.1|WP_046551542.1|1804264_1807357_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	7.75157e-158
NZ_CP011308.1|WP_084722063.1|1822587_1823133_-|HobA-family-DNA-replication-regulator	gnl|CDD|338263	pfam12163, HobA, DNA replication regulator. This family of proteins is found exclusively in epsilon-proteobacteria. Proteins in this family are approximately 180 amino acids in length. The structure of HobA is a modified Rossmann fold consisting of a five-stranded parallel beta-sheet (beta1-5) flanked on one side by alpha-2, alpha-3 and alpha-6 helices and alpha-4 and alpha-5 on the other. The alpha-1 helix is extended away from and has minimal interaction with the globular part of the protein. Four monomers interact to form a tetrameric molecule. Four calcium atoms bind to the tetramer and these binding sites may have functional relevance. The function of HobA is to regulate DNA replication and its does this by binding to DNA-A, but the exact mechanism of how this regulation occurs is purely speculative.	6.80603e-98
NZ_CP011308.1|WP_052746169.1|1816838_1817645_-|bifunctional-riboflavin-kinase/FAD-synthetase	gnl|CDD|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	1.45104e-93
NZ_CP011308.1|WP_046551548.1|1815018_1816842_+|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	4.14041e-68
NZ_CP011308.1|WP_046551545.1|1810564_1811218_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.59367e-62
NZ_CP011308.1|WP_154806494.1|1802517_1803828_-|IS5-family-transposase	gnl|CDD|377531	pfam05598, DUF772, Transposase domain (DUF772). This presumed domain is found at the N-terminus of many proteins found in transposons.	3.22134e-17
NZ_CP011308.1|WP_046551554.1|1823139_1824345_-|aspartate-kinase	gnl|CDD|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0

Protein sequences

>NZ_CP011308.1|WP_179944233.1|1812509_1813859_-|3-deoxy-7-phosphoheptulonate-synthase-class-II
MSWTPGSWRDFPIKQQPTYQDQETLKKVETELSSYPPLIFAGEARNLKRKLAAAGRGEAFLLQGGDCAESFADFNAETIKNLFKLMLQMNMVLMYSTGKPVVKVGRIAGQFAKPRSSDFEEFDGVKLPSYRGDIINGIEFTKEARIPNPHNMIRAYNQSAATLNLVRAFSRGGLADLNKVHQWNLDFIKDNPLGKRYDELSDKIDHAMKFMAACGLTSETMPQLHQTTLYTSHEALLLNYEEALTRLDTETNEWYDCSAHMLWIGDRTRDLNEAHIEYFRGIKNPIGCKVGPSMGEDELIDLIEALNPENEEGRLNLIVRMGAEKIAEFFPPLLKKVRDAGKNVVWTIDPMHGNVEKSSTGFKTRDFDNILSEVKQFFSIHKEMGTVAAGIHLEMTGNDVTECTGSTSCAITAEGLASRYHTQCDPRLNASQALELAFMLSDTISGADQ
>NZ_CP011308.1|WP_046551546.1|1811210_1812401_+|HAMP-domain-containing-histidine-kinase
MFKDSLRNKINLVFSITLVLLASLFIASVKYDHAKFEERNALQERAIAHYLYDYYLKTGKIDEAYLESQNVTLIKDKGQEIQIERYFKEKGKYKKYAVDTFHLQRIILINNDRFKLFLENRNKPKYPVKRIIVFSIVLMFILFLYLWIVRSLKPLSELKNKIKTFSEGNLDISCASNRDDEIAEVANEFDHAVKMIRELLQSRQLFLRAIMHELKTPIAKGRLMSEMLPDEKSKARMHSIFERLNLLIDEFAKIEKITSRNFELHIKPYKMTDLIEASIDILMTENPERLVSIEVKKDYIVKVDFELFTLALKNLIDNAIKYSSDKHVIVTIDEEHVDIINKGKALAEPLENYFKPFHTSRSGLGLGIYIVKSILDIHHMELVYRHEEGNNIFTVK
>NZ_CP011308.1|WP_046551545.1|1810564_1811218_+|response-regulator-transcription-factor
MINILMIEDDPEFAELLSEYLSQFDIKITNYEDPFLGLSAGVKKFDLVILDLTLPGMDGLEVCEELVRKYDLPVIISSARSDISDKVKSFELGAYDYLPKPYDPKEMYARIMSILNRVGKEKGSQNALPKSDFEIKGDTIYFKGQALSLTPAEFEVLSLLVKHQGITQSREQIINTSGTMSIDSQGKSLDVIISKIRSKLGDNKRIQAVRGVGYKLV
>NZ_CP011308.1|WP_046551544.1|1809685_1810483_+|shikimate-dehydrogenase
MTGQLFAIFGNPVSHSKSPLMHNLAFKGLGFEGCYNRYRLEDGTKLKETFFALGLKGINITVPHKEHAYTACDVLDPFARKVGAVNTIVEKEGKLYGYNTDAPGFLKAISEFSNVKKVLFLGAGGTAQSTSAILRDEGYEVTILNRSAGRLEKFEKEGFSTFTFENFSPEVYDLVINMTSAGLEDDALPAPEKILDSVIPSSKACVDVIYGKETPFLKLATQHGKPTKDGSDMLLYQGIIAFEYFTDQRYSFDDIKLHMEKAFTL
>NZ_CP011308.1|WP_046551543.1|1808275_1809682_+|anthranilate-synthase-component-I-family-protein
MMKTVLFDQLTPVALYGKIKTLFPDEITMLFESVVNTSDGNFSFITIGAQERLQYKNKTSYYTDSSGSQKMLDKDPFSFMKSYYASVDQEKYKERALEAGFSFVDGFIGFIAYDMVRVFEPVLSESMDGLLDPLDTPDLDLVRPKIIIAYSHKSAKLTLILNDERMQKGFEQIEEMLHETFTPMALKAVELEGEGTFSIDEERFKALVIESKEHIRSGDIFQILLANRYTQKGKINPLSFYRVLRSKNPSPYLFLLDYEDFSICGSSPEVMVRLTDGEILLRPIAGTRKRGKTHARDKELELEMLNDPKECAEHLMLIDLGRNDVGRVAKTGTVEVTDMMRVEKYSHVMHMVSDVEAVIRDDKDMFDLFAATFTAGTMTGAPKIKAMELIAKFEGLKRGFYSGSVGYFSFNGNMDSAIAIRTSLIKPDSITLQAGAGVVADSIPELEYLEVKNKLGALLATLKEMEKL
>NZ_CP011308.1|WP_052746168.1|1807504_1808272_+|SPOR-domain-containing-protein
MNDHNLDDLIIDNIEPKNNKAKSFLTIIALVIVVLIVAIVFTRTILDTPKNTEIALEENMSGLISPELTLQSTPKVKAPGDETRLSTVIEEKPKTPAATEEIKKETVVVNEKVTVSKKTVAAVPTPKQEVPVKKTAVKKEPAKPEETEKIVVPKKHYVKEETLKPAVKEKVVVPKTDHTASDVKYYIQVGSFSQTPSTRFLNTIKKHGFSYKITAPTANGTKKLLIGPYPSRTDADNALVRVKDRINKGAFIVKK
>NZ_CP011308.1|WP_046551542.1|1804264_1807357_+|efflux-RND-transporter-permease-subunit
MFEKLLRFFVENSRLNYFLFVLVFLTGAVLYTKIPKEIFPSFELDMVSVNGHYAGASIDMLNKMAIKEIEQELKNIDGIDKMATVISAGKFNIILELEKRVDKYNTAEKVKNAIALTRQYLPPDMDEPVVNVLEVKRDLMRVAISSQKASHAALIEAADRLKDKVSALKNIAEVKIYGDSDKYYDIHLDTQKIRAYGLDEDSVIAALTGLSYIFPVGMVEESNAKHFYLSTFNGPKDAKKMLQSRLNIAGKTLYLKDIATVSKRYEDAATLYSIDGKRAVDVSIKQSNEGNALKLAEQIREIVARMNQNSKGIYFTIHNDRSEKIKDRLNIVISNILLGLILIFLLVGVLINKRMSFVITLGIPTSFVMGVIYLYLAGYTINMISLVGVLIALGIIVDDAIVVSENIQQHIEEGMEPKEAAVQGAKEMFQPVTIASLTTMFAFIPALMMSGNMGEVIKLIPIAVSVLVLASLIESFLFLPIHAAHLLNKEEKTTSWERANRIYSKLIHTMMRYRKTFLTLFLILVPLLIVIGIKISKFQMFPKFDASTIRITLKANVNTTTEETMQALRTIEKDLYAHKNEFYIEHVGSVAGWRRDSAGNSESYPYVGNIDIELQKLKAQNFVDRLITPTLSFYYDSEGRTREEKSAVISEKLRAFLKEQHYKERFGLSDLAIVEKKVGPIKSDLKIGLVSDDSQKIMYYAKNIEKKLSSLKGIVSVNDAMHYGVDEIKIEVNPYGESLGLNEKKLGALLSNFYLEKRIGFAFDSSDLLELKVRSSQKDSLEALKQFQVRLPDGSSVSLEDVADFHVVHSFEKLIKDNGLTNFYIYANVNSKILTATEAIDTIKPILDKARKDGVKIIFKGEEEKKKELKHDMMLASAMALLLIMLSLLYLFNSFRETFMMMSVIPFAFLGVLIGHFIMGLNLSMPSIIGMLGLSGVVVNDGIIMLMNLKKAKDIEGIFYYASRRFRPIILTSVTTLIGLGSLIFFPTGQAAIFQPMAVALGFGLAWGTVLNLFYLPALYTILNRKRLGL
>NZ_CP011308.1|WP_154806494.1|1802517_1803828_-|IS5-family-transposase
MLDSNDPLIALADIINWEFFDKSFAKYYSDEGRPAKPIRLMVGLLLLKQLENLSDENVVLQWKRNPYYQYFCGMTEYVPALPCDATELVKFRQRIGTEGVESIFAMSVALHGKDAQEKQVIIDTTVQEKNVTYPTDGKLAIKMIHHLHKIAKEEKIQLRRTYVKEIKGHRISLRFFRHPKKIKKARAAMKRLGTIVGILIRDISRNLNDAQLEKHKEAFDLYTKVINQKRKDSNKVYSLHESHIYAIAKGKDHKKYEYGTKASLVTTMKSNVIIGVTAHQKNEHDSKTLEAALAHANKHRTKPIIEAICDRGYRGKKEVNGTAICIPDSPKKRDTKYQKEQKRKKFRRRAAIEPIIGHVKSDHRMQRNYLKGFIGDQINLLLAAAAFNLKKWMNHFLMVLFLVKITYFTYFMLHIRAEERRKYADLYLNLMLYRLW
>NZ_CP011308.1|WP_046551541.1|1800671_1802177_-|AAA-family-ATPase
MINEISIENFKSFKKLDDLRIKPITIFCGTNSCGKSTLLQSILSIKQTIESQANNQAFLSNGKYVHLGSFENLVYEKKKDNIVKFKFIYNLDTFHNLNLQTVSGIPFRYLIKEIVENTKDEVLFEKTKIIISLSFKSIASKKNKVIRPIRVLNYSIHFETPLKTAGLFNESNILRQHITFRWIKGNRYSITWKNISAHFSKDTQTISGNTKANCAFNNLIPKIQLTSTTDSNNISNLHFFFYRYKELLQALFTTYSYIGPLREEASRRYVYEDEVTEIGLKGENSAYLYITEYENQIKNHYFYNNDQSDFEKKDLTVGKAVDEWLNIMGIEGFGSDVKDEMIHLNLNANKFDETKINIADVGFGISQIFPIVLEGLRMSKQQTLLLEQPEIHLHPKLQMQMADYFISLALSQKNVIVETHSEHIINRLVRRIVEDENNRIQDFIAIYFLQPGENGAKIQEIDIDPIQGVVNWPKDFFDQTASEQEKIILAGLNKRRQKIQK
>NZ_CP011308.1|WP_046551540.1|1799799_1800675_-|hypothetical-protein
MNFVIDPNIVYIDEVSWEDETQKDKYLQYFLDCLKFIDECRDSMFFWSYELESLLWDNPRLPPWRTNIDARNVLVPIIYKKFHSSKTFIDTNCPYDVCQFIPALIESDRFNESFKELCGTLVFEDQNFSMLLGQNQVIPENSEYQYSCSSPDNTQRVKGENIFSKWLKNVDFINHIWPQGINEKEAFENIVIFCTYSEKNTYILKITDTFIRSILTIDLRYKLALINAIKQRLSMTRSQAVSSALQEETIGEEVRIRITPRPTSTRLHFTFENNYIKLKKFYGVGEHDDGL
>NZ_CP011308.1|WP_046552139.1|1814148_1814856_-|carboxy-S-adenosyl-L-methionine-synthase-CmoA
MKDKVFAKPIEKKFEFDQAVASVFDDMLSRSVPFYDEVRHLVISLILAEQKEDMRVLDLGVSTAKFLLDLHSRMDARMQLKGIDNSPAMLERAKQKCRAFGASIDLELADMMAYSYEEEDIIVANYTLQFIRPIQRIELVKRLYEGLNEDGIFIFSEKVVFEDKRLDKMMIDIYYDYKKAQGYSEYEIAQKREALENVLIPFTIEENIRMCREAGFKNINTVFQWANFVTFVAKR
>NZ_CP011308.1|WP_046551548.1|1815018_1816842_+|diguanylate-cyclase
MEKLTVLVVDDDRVSTAILSHMLDNYADKVLIAADGEEGLQLFREHRPEIVLSDINMPRMGGLEMVREIRAIDEHVKIAIFTNFENRDILLKAIQYGVNQFFSKPFEAKLFAQVLQHLVDEVMEKRRIQAELTRQQNILHAINQMSHNFLQQSDWMKALYEEMRNLKTASETSAIFVYKNESDNKEDPLYATQILAINDNKKARAKKRIHYKKHHLMRWKKVLERGQPVNGSINVYDRSKQKLLTAFRIECLLILPIFVNQEWWGFLGIGSNANDPLKKTDVEMLSTVSSIIGSAINNKRNIQSLEMSSMVFKHTMDGVLITNADNRIVHVNSAFTDITGYPASEVIGKDPKLLKSGNHTKQFYDEMWGSINNHSYWQGEIINRKKNGEIYIEWLSINTIRDSEGKIEQHIGIFSDVTHQRKDAQDQAYLATHDPLTGLSNRLVLNDRLEHAIEHAKRFDKYFALIFCDLDNFKPINDTHGHSIGDEVLKHIAGIMKSALRKNDTICRFGGDEFVILIEELKSLKSLKTVLEKIRTRVNQHFTINGLELNVGISIGAAIYPDDAQTPEEILTAADKAMYESKQEGKNRIAFYGSYENFTCSNTYALV
>NZ_CP011308.1|WP_052746169.1|1816838_1817645_-|bifunctional-riboflavin-kinase/FAD-synthetase
MKIQNNIRSIAIGSFDGMHLAHRQVTADVDAIVIIERNGGYLTPGYKRSRYTDKICCFYFFDKIRSLSPRDFVAKLKEDFPHLERIVVGYDFAFGKEKAGNAETLGELFDKEVVIVNEISLEGVPVHSRTIKAYLREGNIFMANKLLGRSYAIEGRVVPGQGLGRESLVSTLNLKVEHYQLPLEGVYASRTKIGKSWHPSVSFLGHRVSTDGSFAVETHIIGEDIGSVEGQVMLEFKALLRRNRKFETLEKLKVQIEEDIANAKKCLA
>NZ_CP011308.1|WP_046551549.1|1817677_1818391_-|TlyA-family-RNA-methyltransferase
MRLDKYLVEEGYFESRNRALEAIKSGQVTVDGKKAKPSVKIDANSQVEVADAKFYVSRAARKLESFLAEHPVKIAQKNALDIGSSTGGFAQIVLENGVASLTCVDVGKEQLHLSIRSDERVSVYEETDIRDFNAETAYEMITCDVSFISILQIMTDIDRLAEKGTDIIILYKPQFEVGKDAKRDSRGVVQDLDAIARKKEVFEAEALSLGWEEEFQALSTLAGKEGNREYLYHFIKA
>NZ_CP011308.1|WP_046551550.1|1818387_1820334_-|NAD-dependent-DNA-ligase-LigA
MTYDEYIANVKTLKKWAYAYYVEDNPVATDEEYDRLYHEVLDYETEHPDKVVEDSPTRRVGGVVRDEFSKAKHIKRMWSMEDVFSKEEVQEWLDRVEKNVGECDYFCEPKFDGASMNLLYDDGKLLRAITRGDGVVGEEVTDNVRTIRSVPLLIDYTGLIEIRGEVVIRKDDFEKINEERLKEGESPFANPRNAAAGSLRQLDSSVTAKRRLVFYPWGVGENMLEYKRLSQKMEFVYAQGFLRPPYHEACKTIDDIEEFYQFLISKRDEIPMMMDGMVIKVDEIEKQEELGYTVKFPRWMCAYKFPAVEKVTKIRAITLQVGRTGVITPVAEIEPVNIEGALVSRATLHNFDEIERKDIRIGDHVIIIRSGDVIPKITKVLVERRTGDEIPVERPTHCPTCGSELLDEGALIKCQNLSCPDRVVNAIIHFAKKGCMDIDGLGAKIVEQLVKEGKIHDMLDLYSLTYEDLADLEGFKEKKINNLLDAIAATKGVPLHRLINAMGIEHIGEVASRALALEFGLGIVDAKYEEIVAIDGIGKEMANSLLEFMRVNREKVLKLFEIIQPTVEEKVEAKENPFKGKTVVLTGTMSESRGKIKEMLEELGAKVSGSVSRKTDFVIYGEDAGSKLAKAESLGVPTLTEDEMRAML
>NZ_CP011308.1|WP_046551552.1|1820601_1821741_-|dihydropteroate-synthase
MYIYKFGNIADKKAALRRLGVESGGIAIMAKKMELFYFYIKDLKTPAANILKQDALSIGAELAVPGGVILCEKPAYDCILIGSRKHMELLSRKELAQPFGLKAVAAELKKFLSLKIYPTKIMGVINANDDSFFAGSRFQESEAVERIEQMIEEGAELIDIGAVSSRPGAEPVSTSVELERIKPICDAIAAEKLFEKAIFSIDSYTPLVVEYALESGFILINDITGAANEEIIRLAVQYGAKLCIMHMKGTPQTMQNDPQYEDVMVEVDTFFQERIARCEAAGMKREDIILDVGIGFGKTLEHNLTLLRNLGHFRHFGCEVLIGASRKSMIDKIIPASTEERLPGTLAIHLKAVENGASIVRCHDVKEHYQALAVQEALA
>NZ_CP011308.1|WP_046551553.1|1821967_1822585_-|DNA-polymerase-III-subunit-delta'
MRLHSQILISNDLEGTILALESAVTTERIVKIIEGEKAFSVDDARLVIEKAYMASEETTVIILAAKIFTPIVQNKLLKVIEEPPAKKEFILVTPSKATILSTIRSRLPIVVLNEERTEADLGLDLPQLSLATVYEFIQSHKRTDAKAMKLLIESISKEAIRSQQYDLDEKTLILFSNAFIALDVGSPSQFVLTTLLLKLLARKKR
>NZ_CP011308.1|WP_084722063.1|1822587_1823133_-|HobA-family-DNA-replication-regulator
MMKELLAWTLETIRNEKSDFSWMEEYRYEWAPLVKSAVSQMLEGKTVLVVTDEHHKWFGQYIINSVNDLGKNRPLLPVYSLNKCFPSLKSLKSTENIQLLEDMFEISYPNGYYIWYIGKGDHPYTKIAYRNEDSFLWIMDEEVQNSFAFRSSDPLLDIKLLQLYKLFDATLSAALFGDLEL
>NZ_CP011308.1|WP_046551554.1|1823139_1824345_-|aspartate-kinase
MLIVQKYGGTSVGGLDRIENVANRVAKARDEGHDLVIVVSAMSGETNKLIEYAEHFSKSPAKKEMDMLLSSGERITAALLAIALQAKGYDAQAMTGRQAGIVTDDTHTYARIESIDPKAMQNAIKEGKIIVVAGFQGINKNGSVTTLGRGGSDLSAVALAAALKADQCEIYSDVDGIYTTDPRIEPHAKKLDTISYDEMLELSSLGAKVLQNRSVELAKKLNVKLYAKSSFSDDKGTLITKENENMEAVMVSGVVLDKNQARVTLRGVVDRPGIAAEIFSALADANINVDMIIQNVGTDGLTNLGFTVPQSELENAKKLVETFNHEIQGVDFDEHVCKVSVVGVGMKSHSGVAATAFTVLADSNINIQMISTSEIKISMIIDEKYGELAIRALHEAYGLDK
>NZ_CP011308.1|WP_046551555.1|1824399_1824873_-|RNA-pyrophosphohydrolase
MQNKKSYRPNVAAVILSSKYPEKCEFFVAHRTDIRNAWQFPQGGIDEGETPEDALYRELLEEIGCNNVEILGEFPEWITYDFPKTARGKVYPFDGQTQKYFLVRLKEDAQINLQAFEIPEFKEYTFVKYDELFQKVTYFKRKVYRRVIDHFIKEGLI

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011308_2	2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996610-996639	30	MN582070	Myoviridae sp. ctThM1, complete genome	53624-53653	3	0.9
NZ_CP011308_2	2.21|996676|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996676-996705	30	MN694606	Marine virus AFVG_250M830, complete genome	33798-33827	5	0.833
NZ_CP011308_2	2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996610-996639	30	NZ_CP027421	Staphylococcus cohnii strain FDAARGOS_334 plasmid unnamed3, complete sequence	3439-3468	6	0.8
NZ_CP011308_2	2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT	995554-995583	30	NZ_CP030761	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence	274575-274604	7	0.767
NZ_CP011308_2	2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT	995554-995583	30	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	11544-11573	7	0.767
NZ_CP011308_2	2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT	995554-995583	30	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	725664-725693	7	0.767
NZ_CP011308_2	2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT	995554-995583	30	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	322794-322823	7	0.767
NZ_CP011308_2	2.5|995620|30|NZ_CP011308|CRISPRCasFinder,CRT	995620-995649	30	NZ_CP011383	Calothrix sp. 336/3 plasmid unnamed1	7649-7678	7	0.767
NZ_CP011308_2	2.6|995686|30|NZ_CP011308|CRISPRCasFinder,CRT	995686-995715	30	NC_015561	Hoyosella subflava DQS3-9A1 plasmid pAS9A-2, complete sequence	43154-43183	7	0.767
NZ_CP011308_2	2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996016-996045	30	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	37537-37566	7	0.767
NZ_CP011308_2	2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996016-996045	30	NZ_CP020429	Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence	67370-67399	7	0.767
NZ_CP011308_2	2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996016-996045	30	NZ_CP020439	Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence	43576-43605	7	0.767
NZ_CP011308_2	2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996016-996045	30	NZ_CP020439	Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence	229010-229039	7	0.767
NZ_CP011308_2	2.14|996214|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996214-996243	30	NC_012853	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132503, complete sequence	283181-283210	7	0.767
NZ_CP011308_2	2.14|996214|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996214-996243	30	NZ_CP025114	Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence	220179-220208	7	0.767
NZ_CP011308_2	2.14|996214|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996214-996243	30	NZ_CP044544	Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence	158359-158388	7	0.767
NZ_CP011308_2	2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996610-996639	30	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	632615-632644	7	0.767
NZ_CP011308_2	2.22|996742|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996742-996771	30	MN693269	Marine virus AFVG_25M487, complete genome	21106-21135	7	0.767
NZ_CP011308_2	2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996808-996837	30	NZ_CP030934	Enterococcus gilvus strain CR1 plasmid pCR1B, complete sequence	23560-23589	7	0.767
NZ_CP011308_2	2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996808-996837	30	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	441749-441778	7	0.767
NZ_CP011308_2	2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996808-996837	30	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	560103-560132	7	0.767
NZ_CP011308_2	2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996808-996837	30	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	237191-237220	7	0.767
NZ_CP011308_2	2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996808-996837	30	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	819680-819709	7	0.767
NZ_CP011308_2	2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996808-996837	30	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	819696-819725	7	0.767
NZ_CP011308_2	2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996808-996837	30	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	272799-272828	7	0.767
NZ_CP011308_2	2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996808-996837	30	MK493321	Cyanophage S-RIM4 isolate RW_11_0999, complete genome	120785-120814	7	0.767
NZ_CP011308_2	2.3|995488|30|NZ_CP011308|CRISPRCasFinder,CRT	995488-995517	30	NZ_CP037428	Myroides odoratimimus strain G13 plasmid pFM-G13, complete sequence	15407-15436	8	0.733
NZ_CP011308_2	2.5|995620|30|NZ_CP011308|CRISPRCasFinder,CRT	995620-995649	30	NZ_CP040085	Acinetobacter baumannii strain VB33071 plasmid unnamed1, complete sequence	5966-5995	8	0.733
NZ_CP011308_2	2.5|995620|30|NZ_CP011308|CRISPRCasFinder,CRT	995620-995649	30	MT176427	Escherichia phage CJ19, complete genome	33643-33672	8	0.733
NZ_CP011308_2	2.7|995752|30|NZ_CP011308|CRISPRCasFinder,CRT	995752-995781	30	MN038175	Panteoa phage Phynn, complete genome	67131-67160	8	0.733
NZ_CP011308_2	2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996610-996639	30	MF417852	Uncultured Caudovirales phage clone 10S_16, partial genome	4125-4154	8	0.733
NZ_CP011308_2	2.24|996874|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996874-996903	30	NZ_CP011383	Calothrix sp. 336/3 plasmid unnamed1	7649-7678	8	0.733
NZ_CP011308_2	2.7|995752|30|NZ_CP011308|CRISPRCasFinder,CRT	995752-995781	30	NC_027120	Lactococcus phage 1358, complete sequence	5216-5245	9	0.7
NZ_CP011308_2	2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996016-996045	30	NZ_AP018258	Calothrix sp. NIES-4071 plasmid plasmid3 DNA, complete genome	51596-51625	9	0.7
NZ_CP011308_2	2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996610-996639	30	KF356199	Microcystis phage MaMV-DC, complete genome	39010-39039	9	0.7
NZ_CP011308_2	2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR	996610-996639	30	NC_008562	Microcystis phage Ma-LMM01 DNA, complete genome	34744-34773	9	0.7

1. spacer 2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to MN582070 (Myoviridae sp. ctThM1, complete genome) position: , mismatch: 3, identity: 0.9

actttaattattaaggagatatagaatggc	CRISPR spacer
aatttaattattaaggagagataaaatggc	Protospacer
* ***************** ***.******

2. spacer 2.21|996676|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to MN694606 (Marine virus AFVG_250M830, complete genome) position: , mismatch: 5, identity: 0.833

cggtga-tgggataatgtcaaaaataatcat	CRISPR spacer
-ggcgattgggataatgtcaaaaagagtcac	Protospacer
 **.** ***************** *.***.

3. spacer 2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027421 (Staphylococcus cohnii strain FDAARGOS_334 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

actttaattattaaggagatatagaatggc	CRISPR spacer
acactaattattaaggagttataaaatgta	Protospacer
** .************** ****.****  

4. spacer 2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NZ_CP030761 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gtgacatgctccaaggcggttatcctgcca	CRISPR spacer
tcaaaatcttccaaagcggttatcctgcca	Protospacer
 ..* ** .*****.***************

5. spacer 2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 7, identity: 0.767

gtgacatgctccaaggcggttatcctgcca	CRISPR spacer
tcaaaatcttccaaagcggttatcctgcca	Protospacer
 ..* ** .*****.***************

6. spacer 2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 7, identity: 0.767

gtgacatgctccaaggcggttatcctgcca	CRISPR spacer
tcaaaatcttccaaagcggttatcctgcca	Protospacer
 ..* ** .*****.***************

7. spacer 2.4|995554|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 7, identity: 0.767

gtgacatgctccaaggcggttatcctgcca	CRISPR spacer
tcaaaatcttccaaagcggttatcctgcca	Protospacer
 ..* ** .*****.***************

8. spacer 2.5|995620|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NZ_CP011383 (Calothrix sp. 336/3 plasmid unnamed1) position: , mismatch: 7, identity: 0.767

aaagaaaattatcgacaacatgacatctga	CRISPR spacer
caggaaaatcatcgagaacatgacatatct	Protospacer
 *.******.***** ********** *  

9. spacer 2.6|995686|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NC_015561 (Hoyosella subflava DQS3-9A1 plasmid pAS9A-2, complete sequence) position: , mismatch: 7, identity: 0.767

ataccccatctggggcagttgctgtaggtt	CRISPR spacer
cacccccatctggggcagctgctgctggat	Protospacer
   ***************.*****. ** *

10. spacer 2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 7, identity: 0.767

ttggagatagaggagcataacaaaaacagg	CRISPR spacer
attgagatagagtagcattacaaaaaacag	Protospacer
 * ********* ***** *******  .*

11. spacer 2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020429 (Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

ttggagatagaggagcataacaaaaacagg	CRISPR spacer
attgagatagagtagcattacaaaaaacag	Protospacer
 * ********* ***** *******  .*

12. spacer 2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020439 (Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence) position: , mismatch: 7, identity: 0.767

ttggagatagaggagcataacaaaaacagg	CRISPR spacer
attgagatagagtagcattacaaaaaacag	Protospacer
 * ********* ***** *******  .*

13. spacer 2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020439 (Streptococcus equinus strain FDAARGOS_251 plasmid unamed1 sequence) position: , mismatch: 7, identity: 0.767

ttggagatagaggagcataacaaaaacagg	CRISPR spacer
attgagatagagtagcattacaaaaaacag	Protospacer
 * ********* ***** *******  .*

14. spacer 2.14|996214|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NC_012853 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132503, complete sequence) position: , mismatch: 7, identity: 0.767

gatatccggtgttgccgtaccgtcaagatt	CRISPR spacer
caactccggtgttgccgtaccttcaaaagg	Protospacer
 *  ***************** ****.*  

15. spacer 2.14|996214|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025114 (Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gatatccggtgttgccgtaccgtcaagatt	CRISPR spacer
gctttccggggtcgccgtaccgtcaagccg	Protospacer
* * ***** **.************** . 

16. spacer 2.14|996214|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044544 (Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence) position: , mismatch: 7, identity: 0.767

gatatccggtgttgccgtaccgtcaagatt	CRISPR spacer
gctttccggggtcgccgtaccgtcaagccg	Protospacer
* * ***** **.************** . 

17. spacer 2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 7, identity: 0.767

actttaattattaaggagatatagaatggc	CRISPR spacer
atactaattattaaggagatataatatgaa	Protospacer
*. .*******************. ***. 

18. spacer 2.22|996742|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to MN693269 (Marine virus AFVG_25M487, complete genome) position: , mismatch: 7, identity: 0.767

ggcactactgaatttggcaatgactactac----	CRISPR spacer
ggcactactgaaattgccaatga----tgcagtt	Protospacer
************ *** ******    *.*    

19. spacer 2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030934 (Enterococcus gilvus strain CR1 plasmid pCR1B, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaagagattgatatactgtataatatg	CRISPR spacer
aaaaaagagattgaaatactgtaaatgtta	Protospacer
.************* ******** *   *.

20. spacer 2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaagagattgatatactgtataatatg	CRISPR spacer
cataaagagaattatatactgtataaactt	Protospacer
 * ******* * *************  * 

21. spacer 2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaagagattgatatactgtataatatg	CRISPR spacer
cataaagagaattatatactgtataaactt	Protospacer
 * ******* * *************  * 

22. spacer 2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaagagattgatatactgtataatatg	CRISPR spacer
cataaagagaattatatactgtataaactt	Protospacer
 * ******* * *************  * 

23. spacer 2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaagagattgatatactgtataatatg	CRISPR spacer
cataaagagaattatatactgtataaactt	Protospacer
 * ******* * *************  * 

24. spacer 2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaagagattgatatactgtataatatg	CRISPR spacer
cataaagagaattatatactgtataaactt	Protospacer
 * ******* * *************  * 

25. spacer 2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaagagattgatatactgtataatatg	CRISPR spacer
cataaagagaattatatactgtataaactt	Protospacer
 * ******* * *************  * 

26. spacer 2.23|996808|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to MK493321 (Cyanophage S-RIM4 isolate RW_11_0999, complete genome) position: , mismatch: 7, identity: 0.767

gaaaaagagattgatatactgtataatatg-	CRISPR spacer
gaaaaagagattgatagactg-acagcacaa	Protospacer
**************** **** *.*..*.. 

27. spacer 2.3|995488|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NZ_CP037428 (Myroides odoratimimus strain G13 plasmid pFM-G13, complete sequence) position: , mismatch: 8, identity: 0.733

gattttaaggtgatatctcttgccggctat	CRISPR spacer
gattttaaggtgatatctatttttgtagtt	Protospacer
****************** ** ..*    *

28. spacer 2.5|995620|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NZ_CP040085 (Acinetobacter baumannii strain VB33071 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aaagaaaattatcgacaacatgacatctga	CRISPR spacer
tatgaaaattatcgacaacacgacctaaac	Protospacer
 * *****************.*** *  . 

29. spacer 2.5|995620|30|NZ_CP011308|CRISPRCasFinder,CRT matches to MT176427 (Escherichia phage CJ19, complete genome) position: , mismatch: 8, identity: 0.733

aaagaaaattatcgacaacatgacatctga	CRISPR spacer
gtcagaacttatcgacaacatgacatgtca	Protospacer
.  ..** ****************** * *

30. spacer 2.7|995752|30|NZ_CP011308|CRISPRCasFinder,CRT matches to MN038175 (Panteoa phage Phynn, complete genome) position: , mismatch: 8, identity: 0.733

agaaacaaagtcgatcagtacgaaaaagag	CRISPR spacer
accgcaaaagtcgataagttcgaaaaagat	Protospacer
*  .  ********* *** ********* 

31. spacer 2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to MF417852 (Uncultured Caudovirales phage clone 10S_16, partial genome) position: , mismatch: 8, identity: 0.733

actttaattattaaggagatatagaatggc	CRISPR spacer
agacgaattaataaggagatataaaatgta	Protospacer
*  . ***** ************.****  

32. spacer 2.24|996874|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011383 (Calothrix sp. 336/3 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

aaagaaaataatcgacaacatgacatcaga	CRISPR spacer
caggaaaatcatcgagaacatgacatatct	Protospacer
 *.****** ***** **********    

33. spacer 2.7|995752|30|NZ_CP011308|CRISPRCasFinder,CRT matches to NC_027120 (Lactococcus phage 1358, complete sequence) position: , mismatch: 9, identity: 0.7

agaaacaaagtcgatcagtacgaaaaagag	CRISPR spacer
caggcaaaagtcgaacaatacgaaaaagac	Protospacer
 ...  ******** **.*********** 

34. spacer 2.11|996016|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP018258 (Calothrix sp. NIES-4071 plasmid plasmid3 DNA, complete genome) position: , mismatch: 9, identity: 0.7

ttggagatagaggagcataacaaaaacagg	CRISPR spacer
ttgaagatagaggagcataactgttggaat	Protospacer
***.***************** .  . *. 

35. spacer 2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to KF356199 (Microcystis phage MaMV-DC, complete genome) position: , mismatch: 9, identity: 0.7

actttaattattaaggagatatagaatggc	CRISPR spacer
cacttaattattaaggagatacaggtatgt	Protospacer
  .******************.**.   *.

36. spacer 2.20|996610|30|NZ_CP011308|CRISPRCasFinder,CRT,PILER-CR matches to NC_008562 (Microcystis phage Ma-LMM01 DNA, complete genome) position: , mismatch: 9, identity: 0.7

actttaattattaaggagatatagaatggc	CRISPR spacer
cacttaattattaaggagatacaggtatgt	Protospacer
  .******************.**.   *.

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	53571 : 64855	10	Emiliania_huxleyi_virus(25.0%)	NA	NA
DBSCAN-SWA_2	295986 : 302819	8	Enterobacteria_phage(33.33%)	NA	NA
DBSCAN-SWA_3	497335 : 505560	7	Bacillus_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP011308|53571:64855|DBSCAN-SWA
AATGAACAATACGATCAGACTTCTGCTTGGTGTAGGTTTTGCTGTTGCAGTGGCTTACTATGCCAGCAGTATCATGGGGCATGGTGGGAATGCAGGATTTATGGTACTTGCAGCAGTATTTGGTGCCTATATGGCAATGAATATCGGTGCGAATGACGTAGCGAACAATGTTGGGCCGGCTTTCGGTTCGGGTGCGATCACCATGGGCGGCGTCATTATCATCGCGGCGATCTTCGAAGCAATGGGTGCGCTGGTCGCAGGCGGTGACGTCGTCGGTACCATCAAAAAGGGGATCATCGATCCGGCGGCATTCGGTGGTGACCCCATGCTGTTTGTATATGCTATGTCTGCAGCACTGCTTGCTGCAGCACTCTGGCTGAATCTTGCAACATGGCTCAAGGCACCGGTCTCTACGACACACTCCATTGTTGGTGGTGTGCTTGGTGGTGGTATCGCAGCGGGTGGTTTTGCGATCGTCTCATGGGGAACCATGGGCAAGATCGCGGTATCATGGGTTATTTCACCTGTACTTGGCGGTGTGATCGCCGCGATCTTCCTCTATATTATCAAGTCACAGATCCTTTATCAGAAAGATATGCGTACTGCAGCTAAAAAAGTGGTACCTGTCCTTGTAGCTATCATGGCTGGAGCATTTCTGACCTATTTGACACTCAAAGGGCTTAAACATGTATGGAGAGACCTTACGGATATGTTGAGCTTTTTGCCTCAGACAAAAAAACCGACATTTATGGCGGCATTGATCATTGGCCTTATTGGTGGGTTCATCACCTATGTAATGGTTAAACCAAGAGTACTTAAAAAAGTAGAGAACGGACTGGGTGAGAACAGAGCCGATATAAACATTTTGTTTGGTATTCCGCTTGTCTTCTCTGCGATCTTCCTCAGTTTTGCACACGGTGCGAACGACGTTGCCAATGCTGTTGGACCGCTGGCAGCAGTGTATGATGCATTGACACATGCAGCGATAGCAACAAAAGCAGCCATTCCGTTGTGGGTCATGGTCGTAGGTGGTGTGGGTATCTCGATCGGTCTGGCACTTTACGGTCCGAGACTGATTAGAACAGTCGGTTCGGAGATCACCGAACTTGACGAGATGAGAGCCTTTTCCATTATGATGGCCGCAGCGATCACAGTCATTATCGCATCACAACTTGGATTGCCGGTCTCCTCTACCCATATTGCAGTAGGTGCAGTGTTTGGCGTAGGTTTCCTTCGCGAATGGCTTGATAGCAAGAATATGGACGAAAAGCAGAAAAAATTGCAAATAGAAGTAGAAAAGCTCGATGCAATCAAGGCAGAGCTCGATGCCCTGAAAAGTGAAGAGGATTACAAAAAACAGGTTGAGCTCATTGAGGCACAGAAAAGACAGAAGAAAAAAGTAAAAAGTATTAAACGTTCTCTTCGTGAGACTTACGTCAAGCGAGGTATGGTCAAGAAGATCATTGCCGCATGGGTCATTACCGTGCCTGCGGCTGCCTTCCTCTCTGCGATCATCTTTTATGTGATAAAAGGGTTTGCGGCCTGACCTGCCTTGTATCGCAATGGTGTTTTTACACTTTTCCTGTAAAAACACCGCATGATTTTCTCTTTCTTTTTCAAACTCCTAATACTTTTTGACTATAATTAGATAAATGGATCACAATGATCCTTTTACAGGTCATTGCGTGCAAATAAGCATGGACAAACGAGGGGTTGGAGCAGCCAATGGATGAAGAACGCATAGAGATCGTTGTGATCGAAGATGAAGAGGATATTCTGGAACTCATAGAGTATCACCTTGCCAAAGAGGGATATGCAGTGACGGGTTTTCTCTCAACGGACAATGTAGAGCAGTTTCTCGAAGAAGAGACACCTGCATTGATGCTGGTGGACCGGAATCTTCCCGGAATGGAGGGAAGCGAGTTTGTTGCCCATCTCCGGAGTACAGGCTATGATATACCGGTTATCTTCCTTACCGCAAAAGACCAGGAGTTCGAGCTGGAAGAGGGCTTTATGGCCGGGGGGGATGACTATATCTGTAAACCGTTCAAGCCCAGAGAGTTGGTATTGCGCATCAAAGCTTTGCTCCGTCGTACCGGTGCACTGCAGCGGCAGGATCGCATCAAATACAAAACGTTGACCATGGACTTTACACAGAAGAAACTGTTTGTTAATAAAGCAGCCGTAGCATTGACCAATCTTGAGTTTAATCTTCTGCATACATTTTTGAAATATATAGACAAGCCTCTGACGCGTGATTTCCTCAGAGAGGAAGCCTGGGGTCAGGAGGGGGAAGGTGTCAATGACAATGCGGTCAATGTCGCCATCAATCGGCTGAAGAACAAGATAGACCCTGAGAATGAAGAGAACTATTTTCATCCGGTATGGGGTGTGGGATACAAATTTTATTAGAATGATACAAAAAATATGTCATTTTGCCATATTTTCTACTTCACTGAAAAGGAAGACGTTACACTGCCATCATGAATAAACTGAAAACACTCGAAGACTATTTTGGACACAAGGCTTTCAGGCCGCTGCAGGAAGAGGTAGTGGATGCTATTTTGAACAGAGAGGATGTGCTGATGATCCTTCCCACGGGAGGGGGAAAATCACTCTGCTACCAGCTTCCCACACTTCTTATGGAGGGTGTGACGGTCGTGGTCTCTCCTCTTTTGGCGCTGATGCATGACCAGGTGGTCGCGTTGCGTGCCAACGGCATTCCCGCTGCCATGCTCTCAAGTATGCAGGACATGGAAGAAAGCCGGCAGATAGAGGGACAGCTGCATCGTGGAAAGATAAAACTGCTTTATGTCGCGCCGGAACGTTTGACCAATGCCTATTTCCTCAATATGCTGCATCAGCTTGACATCAACTTTTTTGTCATCGACGAAGCGCATTGCGTGAGTGAATGGGGGCATGAGTTCAGGGAGAATTACCGGCGGCTTTCGCTGCTCAAAGAGCAGTTTGCTACGACACCTATTGCTGCATTCACAGCTACAGCGACCAAGGCGGTGGAAGAGGATATAGCATCAAATCTTGGTTTGCAGAACCCCAAGCGTGTCAGAGGTTCTCTCTTTCGTGAAAACCTGACCATCCACTCCAGACACCGAATCAAAGACGGGCGTGAACAGCTGCTGGAATTCCTGAAGTCGCATGAAGGGGAGTCCGGGATCATTTATACCCTCTCAAGAAAATCGACCGAATCGGTGGCCCATTTCCTGCAGAATAAGGGTATAGAGGCAAGGGCGTACCATGCCGGTCTACCCACAGAGGAAAAGCATGCGACCTATAGTGATTTTGTGGCTGACAGGGTGCAGGTCGTCGTTGCGACCATTGCATTCGGTATGGGGATTGACAAAAGCAACATCCGTTTCGTGGTGCATATGACACTGCCTAAAACACTGGAGAATTTCTACCAGGAGATCGGACGTGCAGGCAGGGACGGTCTTGAAGCGGAAACCCTGCTGCTGTTCTCCGCACAGGATATCGTACAGCAGAAGATGTTCATAGAGGACCTTCCCGAAACACCCTACAAGCAGCATGCTTTCAACAAACTTGACAGTATGGTACGTTTTGCCAATTCGGAGAACTGCCGTCACCAGAGTATCGCCGCCTATTTTGACGATCGTATCGAAGTCTGCGGAACGAAATGTGACAACTGTACGACAACACAGAGTGAAAAGATTGACATTACGACGGCTGCACGGATGCTGCTTTCGACTATCCTGCGTACCGAACAGAAGTTTGGACTGCATTATGTGATCGATGTGCTCAGAGGAAGCAGGGAACAGCGAGTGCTTCAGAACGGGCACGATACTCTTTCGGTCTATGGCATAGGAGAGGAATACAGCAAGGCACAGTGGATGACCATCGGAGACAAGCTTCTGGAGCTCGGTGCGGTAGAAATAGGTGAGTTCAAGGTTTACAGATTGACGAACTTTGGTGTTGAGGTCATCAAGGGTGCACACAGCATCGAGTTGAAAAAAGAACGCCTGGCAGTCCAAAAGGCCAAGCCAAAACGCAAGGTCACCTATTTTGACGACTATGATGCCGAAGTGTATGACAGGCTCAGAGAACTGCGTACACAGATCGCATCGGAGAAGGGTATACCTCCCTACATCGTCTTTTCGGACAAAACACTCAAAGACCTTAGCAATAAACAACCGCAAACGAAAGGTGAGATGCTGGAGGTGCATGGCATAGGAGAAGTGAAGTTCGAGAGGTACGGAGAGGCATTTTTGGAGTTATTGACAGTGTAGGGTGTTGTGCCCTCACAACACCAAAAACCTTGAATTGGCATACGATTATGAAATGTCTTTTAATGTTTGGATAATCGGTGTTGTCATGGGAGAACACCAATAATATAAACACAAATTTGGAGATAAAATGCAAAATGAAACAAAACCCCTCTGCGGCATTGATGAAGCAGGCAGAGGACCGCTTGCTGGTTCACTTGTGATAGCCGGTGTGGTGTTGACAGGTGAGGTAGAGGGGTTGATGGATTCAAAGAAACTGACTGAAAAGAGACGTGAGGTACTTTACATGCTTGTGATCGAAAATGCCGAGTATCACATTGTTTCATTTTCGGCAAAGGAAGTGGACGGCTTTGGCATCTCGAAGTGTTTACAAAAGGGTTTACAGTCCATACAGAAAGCACTTGACGGATGTGAATATCTCTTCGATGGCAACAGCACTTTCGGCGTGGATAATGTTAGTACGATGGTCAAGGCGGACGACAAGGTCCCTGAAGTTTCGGCTGCAAGTATTCTGGCAAAGGTAACACGCGACAGAGAGATGATAGAAATGGCTAGAGTCTATCCCGAGTATGGGTTTGAGAAGCACAAAGGTTACGGTACCCGATCGCATATCGAGGCTTTAGTGAAGTATGGCAGGTGTGAAATACACCGAAAGACCTTTCGGGTGAAAGGACTGGACGAACCGACACTCTTTTAGAAAGAGATTCCGTTCACAGTTATTTTTCCTTTCACAAAAACGATATCGTATATTTTCTTTCCCTCTTTGGTCGCAGGCGGAACCATCATCATCATGATCATCGCTCTTGGGTCCTGGATAATGAGGGCATAGAGTTCGTCGGAGACGGAAATATGTGTCCTGATATCGATCGCATCGAGTGCAAGAAGAGGGTTTTGGGAGACGGCATTCATATCGAATGATTTGGCAATACTGACTGTACCGTTCATATCGAAGCCGTTCAGGTTTTTTCCATTCTCTGTGATCTTTTTGGCAGAAAATTTGTTCAATGTCAGGACAATGCCTTTTGAAAGCAGATGCTGGGTGAGTTGATTGATATGTGCTTCATCTTCAGGCTCGGTCTTCTGTAATGCTTCAAGCGCAGCAACATCGAGGTTCTCAGCGGTAAAGTCAAACCGGCTCTTCTCGATCGTATATTTTTTTTGTGCCTGATTGATCTCCACCGTTTCGGCTTTGGTGGTCACAATGCTTTTGAGCAAGCCCTGGTTGACGCTGTTTTTTGTTTCATTCTCAATATTTTTGATCTGTAGTGAAAGTTGCGGTTCCATATGAACGGCAATGGACCCGGTGCGGTAGCGTGAAGTGATATCGTAGGGTGTGGTACCTGTACGGATATAGCCACCGTCGATGTCAGAGACTTTGACCTGAAGCGCTTTGCCGGCATCAAGAGAGAGCAACGCGATCTTCTGGGAAAACTGACTGATCTTCTCCTCTTTGCTCTCTCCTTCAAAAGTCATCCCTTTGGCTGCAATAGTTGCTTTTTCACCATCCTCTTCAATGGTTTCATTGATATCTTTGATATAGCCTTTGAAACCCGAGAGCATTTTGTTGAAATCAATATGAAGCAGCAGTGCCTTTTTGGCAAGCATACCTCTGAGATGATTGACCAGCTTTTTGTCTTCCTCTCCCAGCTCTTTCCTCATGCTTTCGGGCAGAGTAACGGGGTAGAGGTCAAGAGAGACTGCGCTGTAACTGTCCGGGAGGTATGCGGCATCTACGCCAACTTGCAGGCCTTTGATGGCCTTGGCATCTTCTATGCGCATCTGGGCACCCTGTGCGTTCAGGTACTGTACGATCTTTTCGGGGTTATCGAAAGAGACGATGAAGTGATCTTTTTTCTTTTCACTTTTTCTCTCTTTGACGGAGAAACCGCTCTGCTGCAGTGTGCTCAATTCGTTGTTGAGCTGCTGCTTTGCCTGCCTGATGATCTGTGCAGATCCGTTCGTAAAATAATAGACCACTGCGATCAGAACGAGTCCGACAAGACCAAAAGCGAGTTTTTTCATACTGATTTCTTTGTTTCGGGATAGATCGCTTTAAGGTGATCCATCTTCCTGCCCATGTTGAGCAGGGCCATATCGGCAAGGGTAAGTGCCATCATCGCTTCGCAGACCACGGCACCGCGTATGGCGACACAGGGGTCATGCCGCCCTTTGAGATTGCAGGTCACCTCTTCATTGTGTGTCGTGATGGTCTGCTGTTCCCGGAAAATGGAAGGGGTCGGTTTGAAATGGGTCTTGACGATGAGTGTATCACCGTTGCTGATACCGCCGAGCGTACCGCCGGAATGGTTGCTCTTGAATCCCTGAAGCGTGATCTCGTCATTATTCTGTGAACCTTTGAGATGGGTACTGGCAATACCGTCACCGATCTCAACGGCTTTGGCGGCATTGATCCCCATCATCGCCTCTGCCAACACGGCATCGAGTTTGTAGTAGAGCGGTTCGCCAAGGCCGACAGGCACACCGGTTGCCGTGGTCAGTACCACACCGCCTACAGAATCATGGTTCTCTTTGGCTGTCAGTATCGCTTTCTCCTGTGCTGCTTCAACAGCAGGGTCAAGCGCATAGAGTTTGGAACTTTTGGCATACTCAAAATCCTGTACATTCCCTTTGATACCGTCCACTTCACACAGTCCGCTCTGTATCTCCACACCCAGCTCTTTGAGCATCAGTTTTGCGATTGCTCCTCCTGCCACACGTGCAGCAGTCTCTCTGGCCGAACTTCTCCCGCCGCCGCGATAGTCTCTCAGTCCGTATTTGTGAAAATAGGTGAAATCGGCATGTCCGGGGCGGAACAGGTCTTTGACATTGTCATAATCTTTGGATTTCTGATTGGTGTTGAAGATGATCATCGCAATAGGCGTACCGGTACTCAGGCCTTCGAAGACACCGGAGAGTATTTCGATCTTGTCGTCTTCCTTGCGTCCGGTCTCCAGTTTGCTTTTCCCCGGTTTGCGTCTGTCGAGGTCAGACTGGATGAAGGCTTCATCTATATGGAGCCCGGCAGGCACACCGTCAAGTATGCATCCGATCGCTTTCCCGTGGGACTCGCCAAAGGTGGTGAGTGTCAGTCTCTTTCCAAAGGTATTCACTGTCTATCCTTTCAGTTTCTCTAAGGCAATTTTCGCCGCTTTCTGCTGCGCGTCTTTTTTGCTTTTGCCTTTGGCTGACGCGATGGTTTCATTGTCAAGGATGACAGCGATCTCGAACTCTTTTTTGTGGTCGGGGCCCGAAGAACCGAGCATCTCATAACTTGGTGTCACGCCGTGTGTCGCCTGTGTCAACTCCTGTAAAGCAGTCTTGTAGTCTTTTGACAGGCTTTGCAGGTCTATTTTGGGATGACACTCTTCCAGCAGTTTGATGGAAATCGTTTTAGCCGTATCGAGGCCGGCTTCCAGATAGACGGCTCCTATAACCGCTTCAAAGGCATTGGAGAGCAGCGACGGCTTGTCTCTTCCATTGTTGTTCTCTTCCGCGAGAGAAAGGAAAATGTAAGAGCCCAGGTCGATCTTTCGTGCCAGAAGTGTAAACCCGCTTTCATTGACAAGTGAAGCTCTGATCTTGGAGAGAATTCCTTCATCCGACTTGGGAAATTTTTTGAAAAGGTACTCGCCTACGATGAGGTCGAGGACTGCATCTCCCAAAAATTCAAGCCGCTCATTATTGTAAGGCTTCTTGTAACTTTTGTGTGTCAAAGCCTCAATAATCAACTGCTTGTCCCTGAATGTATAGTTCAGTCTTTTTTCAAGCTGACTGTAGTCGTTCATTGTTTCGTTCCTTTTTTGAGTTTTGTAGCCTTGATGCGTTCCGCTTCGTTCCGTGCCAGTTCATCACAGCGTTCATTTTCGGGATGCCCGTCATGCCCCCGTACCCAGGTACCATGAACATGGTGGGGTGCGGCAGCTTCAATATACGCTTTCCAGAGATCAACGTTTTTGACTTTCTTGAAGTCCCTTCTTATCCAGCTCTCCAGCCATTCATTGATAGCTTTGACCACATAAGAGCTGTCGGAGACCACCTCCACATCACAGGGCTCCTTGAGCAGTTTCAGTCCTTCGATGACCCCGCGAAGTTCCATACGGTTGTTCGTTGTCTCTTCTTCTCCGCCAAAGTACTCTTTGCGTGAGCCTTTGTACTCCAGTATGCCGCCATACCCGCCCGGTCCCGGGTTGCCGAGGCTCGAACCGTCAGAGTAGAGAGTAATCTGTTTTCGGGCTTGCTTTTGCAATCTTTTCCTCCACTTCCACAGAGTTTATCGCCATACAGTTTGGACATCTTTTGAACGATACGGGGAAGCTCTGTTTACATTTTTTGCAGAGATAGGAGAAAAGAAGGTCCCCCTCCTCAAATCCGTTCTCTCTTGCCGTTGCCAGCATATCCACTGCGAAGATACCGCTATGGAGCAAGGGCTTCTGCAGATATCCTTTGGCGTAGTAGAGAGTACTGAGCCTCTCATCGGATGTGATTATATCCAAATCGACTTGTGAATTCGGTAAGAACCAAAGGATGTCTATCGTCTCCTTGATCCGTTCAGGATCGATGATCTTCCAGGCTTCGGTCGTGTCAAGTTTCAGGAGAGTATCTACGATCTGACGGTAGAGTTTTGGCTCCTCAGCAAGGATCTTTTTCAGCGCTGCTACCTTCTCGTCGGTACCGAGCATCTTGTTAGACGTCAGTGCGGAAAGTTCAAGAAATTTGCTGAGCGTATGCGTATCTTTCCCCAGGGTATTGAGTGGCTCGATGATCTCCTGTGCCTTGTCGTATTTGTGCATCATTTCATAGACAACCCCGAGTTCGTAAAGCACTTTGGTGTTGCGGGGACGTTTGCGGAGTATTTCCGTATAGATCGACCTGGCGCGCTCGAGGAAACCGGCATGCAGGTAAGTATTCCCCAGTCTCTCCATCAGTTCCATTTTGGTAAAGTCATCGTCGATATGCCTCGTGACGTAGAGATAGATGCTGATCGCCTTGTGGTATTCACCCGAATTTTCAAAGGCTTTGGCAAGAAGCGTAAGCGGCTTGAGCATATGTCCCTCGAAAGGCATATCGTCCGTATCGAGAGCACATTCGGAACTGTCGAACTTGTCAAGGAATTTCAGGAGGTTCCCCTCCTCCTTCTGCTGCTTGTAGAGCCCCCAGGCATAGGTGACAACAGAGATGATCAGTGCGATGACAATGATTAGCAGAATGCTGAACAGCGGATCGTTGTATGCCGGCAATATCGTTTCCAAGAAGTTCCTTTAGCCTGTTTAGTCCTTGGATTATATCAAATTAGATATAATACCACTATGATAGATAACGCTTACCTTTTTTTCCTCTCACTGAAGCTTCGTCCTTGGCAAGAATGGATGCATTATGATCGATAATGCCTCCATAGAATCCCTCAAGAACAGTATCGATATCGTTGATGTGATAGGGAACTTCATTGAATTGAAAAAAGCCGGGGCTAACTATAAAGCGAACTGCCCTTTTCATGGTGAGAAGACCCCCTCTTTTGTCGTGAGCCCCAGCAAGCAGATATACCACTGTTTTGGCTGCGGCGTAGGCGGAGACAGCATCAAGTTCGTGATGGAACTGGAGAAGCTTTCCTACCCCGAAGCAATCGAAAAACTGGCATCGATGTACAATTTTTCGCTCAACTATACCAAGGGGTCTTCGGACTACTCCGATGCCAAACGAGTACTCGAGACCATACAGGCCTGGTATGTCAAGAATCTGGAAAACAACCCCACGGCTAAACAATATCTTCTCGACAGGGGGATCGCACAGAGTTCCATAGAGCGTTTCGGTATCGGGTATGTCCCCGACGGCAACTCCGTGATCCATTTTCTAAACTCTGCACTGTTGCCGCTTCCCAAAGCGGTGGAAGCGGGCATTCTGGCACAGGGTGAGGGCGGAAGGTATTATGCGCGTCTGGTGGAACGTATCACTTTTCCCATATACTCTACCAGCGGCGGGGCTGTCGGTTTTGGAGGACGTACTATTACCAACCATCCGGCAAAGTATATCAATTCACCGCAGACCAAACTCTTCAACAAATCCAGACTGCTTTACGGCTACGACCTGGCAAAAGAGAGCATTTACAAAAATAAAAAGCTGATCGTCTGTGAGGGCTACCTCGATGTCGTGATGTTCCATCAGGCAGGTTTTACCGAAGCCGTCGCTACTCTGGGTACGGCACTGACGGCAGAGCACCTGCCTCTGCTCAGAAAAGGTGATCCCAAAGTTATTCTTGCGTATGACGGAGACAAGGCAGGAGTAGCTGCAGCATTGAAGGCAGCACAGATGCTGAGTGTTTCGGGCTTTGACGGTGGTGTGGTTCTTTTTCCCGACGGGCAGGACCCGGCCGATCTCATCGCCAAAGGGCAGAGCGAAGCGGTCGCCAAACTGCTGCGTGAAGCCAAGCCGCTCATTCCTTTTGTATTGGAACAGACCATCTATGCCTACAACCTGCACGATCCTCGTGCAAAAGAGGCGGCATTCGGGGCTGCCAAACAGTTCCTTGATGGCTTGAGCCAGATCATAAAGGATGCCTACATTCCTATGACAGCGACACTGTTGGGGGTTTCTCCTGCACTGTTCGGAAAGCAGACACAGCCAAACCGCGCCAAAGAGAGTTTTTCTCAAAAAAGAGATGACGTGGCACAGTTGAGCATACTGAAAACACTGCTGGAAAAACCCGAACTGATCGATTCGGTACTCGATGTCATCGATGTCAATATGTTCGGCGGTTATGCCGCCATGTTCTCGGCACTGATCAGCGGGGAGAAGGAGCATCCGCATTTGATGGGACTGGCCGTAGACGATACCTTCCAGATAATGGACGAAGCAGAACTTCAGGGGGTGCTACGGAACTTTTTGATCAAGCACTACGATATGAAACTCAAAAATATCGTGGCAGACCAGACCATACCTTTTGAGAAGAAGAGTTTTTTGATACGTAAAATAAAAACTGATATAATCCCACGACTCAAGCGTGGAGAACTGGTCGCATTTGAAGGCAATTAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP011308|53571:64855|58522_59851_-|WP_046550137.1|DBSCAN-SWA
MKKLAFGLVGLVLIAVVYYFTNGSAQIIRQAKQQLNNELSTLQQSGFSVKERKSEKKKDHFIVSFDNPEKIVQYLNAQGAQMRIEDAKAIKGLQVGVDAAYLPDSYSAVSLDLYPVTLPESMRKELGEEDKKLVNHLRGMLAKKALLLHIDFNKMLSGFKGYIKDINETIEEDGEKATIAAKGMTFEGESKEEKISQFSQKIALLSLDAGKALQVKVSDIDGGYIRTGTTPYDITSRYRTGSIAVHMEPQLSLQIKNIENETKNSVNQGLLKSIVTTKAETVEINQAQKKYTIEKSRFDFTAENLDVAALEALQKTEPEDEAHINQLTQHLLSKGIVLTLNKFSAKKITENGKNLNGFDMNGTVSIAKSFDMNAVSQNPLLALDAIDIRTHISVSDELYALIIQDPRAMIMMMMVPPATKEGKKIYDIVFVKGKITVNGISF
>NZ_CP011308|53571:64855|53571_55116_+|WP_046550133.1|DBSCAN-SWA
MNNTIRLLLGVGFAVAVAYYASSIMGHGGNAGFMVLAAVFGAYMAMNIGANDVANNVGPAFGSGAITMGGVIIIAAIFEAMGALVAGGDVVGTIKKGIIDPAAFGGDPMLFVYAMSAALLAAALWLNLATWLKAPVSTTHSIVGGVLGGGIAAGGFAIVSWGTMGKIAVSWVISPVLGGVIAAIFLYIIKSQILYQKDMRTAAKKVVPVLVAIMAGAFLTYLTLKGLKHVWRDLTDMLSFLPQTKKPTFMAALIIGLIGGFITYVMVKPRVLKKVENGLGENRADINILFGIPLVFSAIFLSFAHGANDVANAVGPLAAVYDALTHAAIATKAAIPLWVMVVGGVGISIGLALYGPRLIRTVGSEITELDEMRAFSIMMAAAITVIIASQLGLPVSSTHIAVGAVFGVGFLREWLDSKNMDEKQKKLQIEVEKLDAIKAELDALKSEEDYKKQVELIEAQKRQKKKVKSIKRSLRETYVKRGMVKKIIAAWVITVPAAAFLSAIIFYVIKGFAA
>NZ_CP011308|53571:64855|56053_57832_+|WP_046550135.1|DBSCAN-SWA
MNKLKTLEDYFGHKAFRPLQEEVVDAILNREDVLMILPTGGGKSLCYQLPTLLMEGVTVVVSPLLALMHDQVVALRANGIPAAMLSSMQDMEESRQIEGQLHRGKIKLLYVAPERLTNAYFLNMLHQLDINFFVIDEAHCVSEWGHEFRENYRRLSLLKEQFATTPIAAFTATATKAVEEDIASNLGLQNPKRVRGSLFRENLTIHSRHRIKDGREQLLEFLKSHEGESGIIYTLSRKSTESVAHFLQNKGIEARAYHAGLPTEEKHATYSDFVADRVQVVVATIAFGMGIDKSNIRFVVHMTLPKTLENFYQEIGRAGRDGLEAETLLLFSAQDIVQQKMFIEDLPETPYKQHAFNKLDSMVRFANSENCRHQSIAAYFDDRIEVCGTKCDNCTTTQSEKIDITTAARMLLSTILRTEQKFGLHYVIDVLRGSREQRVLQNGHDTLSVYGIGEEYSKAQWMTIGDKLLELGAVEIGEFKVYRLTNFGVEVIKGAHSIELKKERLAVQKAKPKRKVTYFDDYDAEVYDRLRELRTQIASEKGIPPYIVFSDKTLKDLSNKQPQTKGEMLEVHGIGEVKFERYGEAFLELLTV
>NZ_CP011308|53571:64855|57959_58526_+|WP_046550136.1|DBSCAN-SWA
MQNETKPLCGIDEAGRGPLAGSLVIAGVVLTGEVEGLMDSKKLTEKRREVLYMLVIENAEYHIVSFSAKEVDGFGISKCLQKGLQSIQKALDGCEYLFDGNSTFGVDNVSTMVKADDKVPEVSAASILAKVTRDREMIEMARVYPEYGFEKHKGYGTRSHIEALVKYGRCEIHRKTFRVKGLDEPTLF
>NZ_CP011308|53571:64855|59847_60939_-|WP_046550138.1|DBSCAN-SWA
MNTFGKRLTLTTFGESHGKAIGCILDGVPAGLHIDEAFIQSDLDRRKPGKSKLETGRKEDDKIEILSGVFEGLSTGTPIAMIIFNTNQKSKDYDNVKDLFRPGHADFTYFHKYGLRDYRGGGRSSARETAARVAGGAIAKLMLKELGVEIQSGLCEVDGIKGNVQDFEYAKSSKLYALDPAVEAAQEKAILTAKENHDSVGGVVLTTATGVPVGLGEPLYYKLDAVLAEAMMGINAAKAVEIGDGIASTHLKGSQNNDEITLQGFKSNHSGGTLGGISNGDTLIVKTHFKPTPSIFREQQTITTHNEEVTCNLKGRHDPCVAIRGAVVCEAMMALTLADMALLNMGRKMDHLKAIYPETKKSV
>NZ_CP011308|53571:64855|63202_64855_+|WP_046550142.1|DBSCAN-SWA
MIDNASIESLKNSIDIVDVIGNFIELKKAGANYKANCPFHGEKTPSFVVSPSKQIYHCFGCGVGGDSIKFVMELEKLSYPEAIEKLASMYNFSLNYTKGSSDYSDAKRVLETIQAWYVKNLENNPTAKQYLLDRGIAQSSIERFGIGYVPDGNSVIHFLNSALLPLPKAVEAGILAQGEGGRYYARLVERITFPIYSTSGGAVGFGGRTITNHPAKYINSPQTKLFNKSRLLYGYDLAKESIYKNKKLIVCEGYLDVVMFHQAGFTEAVATLGTALTAEHLPLLRKGDPKVILAYDGDKAGVAAALKAAQMLSVSGFDGGVVLFPDGQDPADLIAKGQSEAVAKLLREAKPLIPFVLEQTIYAYNLHDPRAKEAAFGAAKQFLDGLSQIIKDAYIPMTATLLGVSPALFGKQTQPNRAKESFSQKRDDVAQLSILKTLLEKPELIDSVLDVIDVNMFGGYAAMFSALISGEKEHPHLMGLAVDDTFQIMDEAELQGVLRNFLIKHYDMKLKNIVADQTIPFEKKSFLIRKIKTDIIPRLKRGELVAFEGN
>NZ_CP011308|53571:64855|60942_61614_-|WP_046550139.1|DBSCAN-SWA
MNDYSQLEKRLNYTFRDKQLIIEALTHKSYKKPYNNERLEFLGDAVLDLIVGEYLFKKFPKSDEGILSKIRASLVNESGFTLLARKIDLGSYIFLSLAEENNNGRDKPSLLSNAFEAVIGAVYLEAGLDTAKTISIKLLEECHPKIDLQSLSKDYKTALQELTQATHGVTPSYEMLGSSGPDHKKEFEIAVILDNETIASAKGKSKKDAQQKAAKIALEKLKG
>NZ_CP011308|53571:64855|62034_63078_-|WP_046550141.1|DBSCAN-SWA
METILPAYNDPLFSILLIIVIALIISVVTYAWGLYKQQKEEGNLLKFLDKFDSSECALDTDDMPFEGHMLKPLTLLAKAFENSGEYHKAISIYLYVTRHIDDDFTKMELMERLGNTYLHAGFLERARSIYTEILRKRPRNTKVLYELGVVYEMMHKYDKAQEIIEPLNTLGKDTHTLSKFLELSALTSNKMLGTDEKVAALKKILAEEPKLYRQIVDTLLKLDTTEAWKIIDPERIKETIDILWFLPNSQVDLDIITSDERLSTLYYAKGYLQKPLLHSGIFAVDMLATARENGFEEGDLLFSYLCKKCKQSFPVSFKRCPNCMAINSVEVEEKIAKASPKTDYSLL
>NZ_CP011308|53571:64855|55295_55982_+|WP_046550134.1|DBSCAN-SWA
MDEERIEIVVIEDEEDILELIEYHLAKEGYAVTGFLSTDNVEQFLEEETPALMLVDRNLPGMEGSEFVAHLRSTGYDIPVIFLTAKDQEFELEEGFMAGGDDYICKPFKPRELVLRIKALLRRTGALQRQDRIKYKTLTMDFTQKKLFVNKAAVALTNLEFNLLHTFLKYIDKPLTRDFLREEAWGQEGEGVNDNAVNVAINRLKNKIDPENEENYFHPVWGVGYKFY
>NZ_CP011308|53571:64855|61610_62075_-|WP_046550140.1|DBSCAN-SWA
MQKQARKQITLYSDGSSLGNPGPGGYGGILEYKGSRKEYFGGEEETTNNRMELRGVIEGLKLLKEPCDVEVVSDSSYVVKAINEWLESWIRRDFKKVKNVDLWKAYIEAAAPHHVHGTWVRGHDGHPENERCDELARNEAERIKATKLKKGTKQ

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046550133.1|53571_55116_+	inorganic phosphate transporter	G9E3M1	Emiliania_huxleyi_virus	1.5e-16	41.5
WP_046550134.1|55295_55982_+	response regulator transcription factor	W8CYM9	Bacillus_phage	9.4e-24	31.8
WP_046550135.1|56053_57832_+	DNA helicase RecQ	A0A2K9L021	Tupanvirus	1.7e-80	35.8
WP_046550136.1|57959_58526_+	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	2.1e-21	36.3
WP_046550137.1|58522_59851_-	DUF945 family protein	NA	NA	NA	NA
WP_046550138.1|59847_60939_-	chorismate synthase	A0A291AU41	Pandoravirus	7.1e-74	43.5
WP_046550139.1|60942_61614_-	ribonuclease III	L7RCJ8	Acanthamoeba_polyphaga_moumouvirus	7.7e-31	35.6
WP_046550140.1|61610_62075_-	ribonuclease HI	Q2Z0V7	Pseudomonas_phage	2.7e-22	39.5
WP_046550141.1|62034_63078_-	hypothetical protein	NA	NA	NA	NA
WP_046550142.1|63202_64855_+	DNA primase	A0A1S5RH70	Helicobacter_phage	1.4e-57	28.2

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP011308|295986:302819|DBSCAN-SWA
GATGTCACAAGAGAACAACAAAATAGCGATGGATATAGAGGGATACCTCAAAGAACATGAGAACAAGGACATGCTGCGTTTCCTGACCTGCGGGTCGGTAGATGACGGAAAGAGTACATTGATCGGGCGTATGCTTTATGATTCAAAGATGATCTTTGACGATCAGCTTTCAGCGGCGGAAGGTGAGAGCAAGAAGTATGGGACCACCGGCGAGAAGATCGATATGGCTCTGCTTGTAGACGGACTTCAGAGCGAACGGGAACAGGGGATTACGATCGATGTCGCCTACAGATTCTTTGCAACCGAGAACCGAAAGTTTATCATCGCGGACACTCCGGGCCATGAACAGTACACCAGAAATATGGTGACAGGTGCTTCTACCGCGGATGTGGCGATCATTCTTATCGATGCACGCAAGGGGATATTGACGCAGACAAGACGACACAGTTTCATCGTGAACCTGCTCGGTATAGAACATGTGATCGTTGCGATCAACAAGATGGACCTTGTGGATTTCAGCGAGGAGGTTTATAACGACATCTCCAAAGCCTATGGTGTACTGGCAGATGAACTGGGGATCAAAAATACCTATTATATCCCCGTTTCTGCGCTGGAAGGGGACAATGTAGTCGATAAAAGCGAGAAGATGCCATGGTATACCGGCATGCCGCTGCTTGGACTGCTGGACAGTATGGATATCTCCAAAGAACAGACGGCGGAGAATTTCAGACTTCCCGTACAGTACGTCAACCGTCCGAACCTTGATTTCAGAGGTTTCTGCGGGACCATAGCCGCAGGTGAAGTGAAAGTGGGTGATGAGATCACAGTGTTGCCTTCAGGAAAAACGACCAAAGTGAAGAGTATTATCAATGCGGGTGACATTACCGAAGACAATAGAACGGCGACAACCCAATTCGCCTATGCGCCTATGGCCGTGACCATTACGACCGAAGATGAGGTCGATATCTCGCGTGGTGATATGATCGTACATACGAAGAGTCTGCCGAGAGTATCGAACTCACTCAAGGTCATGCTGGTATGGATGGACGAGACACCTATGGAAGTCGGAAGATCTTACGATATCAAGCGGGCTACTTCAGTCGTATCGGGTGCCTTTGAACATATCAACTATAAGGTCGATGTCAATACCTATGAGAGAGAGCAGGTGCACAGTCTCGGCCTGAATGATATCGCTTCGTGCAAAATGGTCCTGACACAGCCGATCGCAGCGGATGCGTATGAAATGAACCGCCTGACGGGATCATTTATTGTCGTGGACAGGATCACCAACAATACTGTCGGTGCAGGAATGATCGTCGGTGTGAGCAGACGTGAAGAGGATGCCGCAAAGCTGTCGGAAAAAGAGTATACCGATGCAGAGAGAGCGTTGAACCAGTATATCAGAGAGAACTTCCCTGAATGGGAATGTAAAGTCGTCTAATGTACAGAGAGACCAACCAGCGTTCGATCGTCAAGGGGATCAGCTGGAGGGTTGTGGCCACGACCACGACCATCCTGATCGTCTATTTTTTCTTTGACCGGCTGGATCTTGCTATTGCTGCAGGATTGATCGAAACGGTCCTCAAAGTAGCTCTCTACTGGGGACATGAAAAAATATGGCAGAGAATCCACTGGGGAAAGAAGAAGATAGACCCTTTCAACCTCTGGTTCACAGGCTTGCCGCTCTCGGGAAAAACCACGATCGCGGATAAGGTCTATACTGAGCTGGAGAAACTGCATATCCCTATTGAACGTATCGATTCGAAAGATATCCGAGACCTGATCCCCGATATCGGCTATACGCGGGAGGACAGGAACAGACATATGCACCGTATCGGTTTTCTGATTCAGAGACTGCAGAAAAATTCCATTTCTACGGTAGCGACCTTTGTCTCTCCCTATACGGAATCACGCAAAGCGATACGGGAGATGGTCAAGAACAATATTGTGATCTATGTCAAAGCCGATATAGAAACCTGCAAATCCCGTGACTATAAGGGGGTCTATGACAGAGCGATGAAGGGTGAATTGAAAAACTTTTCCGGCATCAATGATGTCTATGAAGAACCACAGCATGCGGAGATCACGGTAGATACGAACAAGTTAAGTGCAGATGAAGCTGCAGAGATCATAGCAAAATACGTAAAGAAACATTATGTCAAATGAGAATATTGTATGGCATGACCATCATGTCACCAAAGAGGAACGTGCCGCCATTAAAACACAAAAACCCTGTATACTCTGGTTTACAGGGCTGAGCGGTTCCGGAAAATCCACCGTTGCGAATGCAGTTGAGAGCAGACTGCTTGCACTGAAAAAGCACACCTATCTGCTGGATGGGGACAATATCCGTATGGGGCTCAATAGAGGTTTGACCTTTTCAGATGAGGACAGGGTAGAGAATATACGCCGTATCGGTGAAGTTTCCAAGCTTTTTGTGGATGCGGGGACTATCGTTCTGACAGCGTTTATCTCTCCCTTTCAAAAAGAGAGAGATGCGGTACGTGCACTGGTGGAGAAAGATGAATTTATTGAAATTTTCATAGATACACCGATAGCAGTCTGTGAATCGCGAGATCCCAAAGGTTTGTACGAAAAAGCGCGTAAAGGAGAAATTCCGAACTTTACAGGTATTTCTTCTCCATATGAAGCCCCTGCAGAAGCTGAAATACATGTTAAAACAGAAGATCAGACTATCGCCGAATCGGCGGAGCAGGTTATCGGATATTTAAAAGAAAAAGGTTACATAAATGCTGGATAAAATCGATTTAAACGATATTCAAAAGATCGCGCAGGATGCAGGCAATACCATTATGGAGATATATAACAGAGATTTTTCCATCGAATATAAAGATGACAAGTCCCCGTTGACCGAGGCAGATACGGCTTCTCATGAAGTGATCATGGAGGGGTTGGAGAAGTACGGCATACCTGTGATGTCCGAAGAGGGAAAGACCATCACCTATGATGAGAGAAAAGGGTGGGAATACTACTGGTGTGTCGATCCCATAGACGGGACAAAAGAATTCATTAAGAAAAACGGTGAATTTACGGTCAATATTGCGTTGATCCATAAAGATACACCGGTTCTGGGGGTAGTTTATGCCCCGGCGCTGGGAGATATGTACAAAGCTAAAAAAGGAGAGGGTGCTTTTAAGAATGACCAAAAGCTTCCTCTGTGCAGCAATCCTGACCAGAAAGAAAAAATGAGTGTTGTTGCATCCAAATCCCATCTTTCCGAAGAGACACAGGCTTTTATCGATGCACTTGATACGCGAAATATTGAACAGGTATCCAAAGGAAGTTCTCTGAAACTTTGTATGGTGGCTGAGGGAGAAGCCGATATTTATCCTAGGCTTGCTCCTACGATGGAGTGGGATACGGCAGCAGCCGATGCAGTCGTAAGAGAAAGTGGAAAGATGACCTGTCAGTTTGAAAATGACAGACCTGTAGTCTACAATAAAGAGAATCTTTTGAATCCCTGGTTCGTGGTAAAATAATAGTATGAAAGGTATTATTTTAGCGGGGGGATCCGGGACAAGACTCTATCCGATTACTAAAGGTGTGAGCAAGCAGTTGGTCCCCATTTATGATAAACCGATGATTTACTATCCTCTTTCTGTACTCATGCTTGCAGGGATCAAAGAAGTGCTGATTATCTCTACACCGCAGGATCTCCCGAGATTTGAAGAATTACTGGGCGACGGAAGCAATATCGGTATGCAGTTCTCTTATATGGCACAGCCGTCTCCTGACGGGTTGGCACAGGCCTTTTTACTGGGAGAATCGTTCATTGGCGATGATAATGTCTGTCTTATTCTGGGGGACAATATATTTTACGGTCATGCATTGACGGAACTGTTGAAAAAAAGTATTGCAAATGCTGAAATAGAGGATAAAGCAACCGTGTACGGGTATTATGTCAGTGACCCTGAACGTTACGGTGTAGCGGAGTTTGATACAAGGGGTAATGTTGTCTCTTTGGAGGAGAAACCGAAATACCCCAAAAGCAATTATGCCGTGGTAGGACTGTATTTTTATCCGAATGATGTCGTGAAGAAAGCCAAGGAAGTGAATCCTTCAGATCGCGGTGAGCTCGAGATCACTACACTGAACCAAATGTATCTTGAGGAGGAAAGACTTCGGGTGAAACTCATGGGTAGAGGATACGCATGGCTCGATACGGGTACACACGAGTCTCTGCTTGAAGCAAGCCAGTTCATACAGACCATTGAGAAGAGACAATCTCTGAAGGTAGCCTGTATCGAAGAGATTGCGTATGAGATGGGGTATATTTCCAAAGAGCAGTTACTTACCCTGGCAGAGCCGTTGAAGAAGAGCAATTATGGTCAGTATCTTATTCAAAGAGCGCAATAGGAGAGGGAGTGGAAAATGAACTTTATACGTACAGAGATCGAAGATGTTGTGATAGTTGAACCTGCGATTCATGGTGATGAGCGAGGATATTTTGTAGAAACATTCAGGCAGGATAAACTTTCCGAATTTCTGGGATACACAATAGATTTTTGTCAGGACAATGAATCCAAAAGTTCTTATGGTGTTCTTAGAGGGTTGCATTATCAACTCCCACCTCATGCACAGACAAAGCTGGTACGTGTTATACAGGGACGTGTTCTGGATGTTGCTGTGGATATTCGTAAAGGAAGCCCGACTTTTGGACAACATGTTGCCGTTGAATTGAGCGGTGAGAACAAACGCCAGCTTCTGGTTCCCCGGGGATTTGCGCATGCATTCATCGTATTGGCCGATGATACGATATTTGCCTATAAAGTGGATGCCTACTACTCTCCGGAGTGTGACAGAGGCATTTCCTATGCCGACAAAGATTTGGGGATTGAATGGCCTATGCCTTTGGAAGAGATAAAGCTTTCAGAGAAAGATACCAGGCAACCGGAACTGTATGAGACAGATGATCTGTTTGAATACGGTGTGAACTACTATGCCTAATATACTTGTGACGGGGAGCAGAGGGCAGCTGGGGAGTGAACTTCGTGAACTTGTTAATAATAATGCAATATTTCACTTCACAGATAGAAGTGTATTGGATATAACAGATCAAGATGCAATAAAACATTTTTGCCTTGAAAAAGATATTGAAGTGATTATCAATTGTGCCGCCTATACGGCTGTAGACAAAGCGGAAGAAGATGAGGAGAATGCTGATAGGATCAATCACCTGGCTGTCAAGTATCTGGCACAGATCGCCAAAGAGCGGGAGATCAGATTTGTACATATCTCAACCGATTATGTTTTTGACGGTACGAACTTCATGCCCTATGTTGAAAGTAATAGGACAAACCCCACCAGTGTGTACGGAAGGACCAAGCTGGCAGGGGAAGAAGCAATACGGAAGATCAACCCGGACAATACGGTAATTATCAGAACATCATGGGTTTACAGCACCTACGGCAGCAATTTTGTCAAGACCATGTTGCGTCTGGGGAAAGAAAGAGATACATTGGGAGTAATATTCGATCAAGTGGGTACACCGACCTATGCACGGGACCTGGCACAGGCGATCCTGGATATTGTGCCACAGATAGAGAATAAAGAGGTTGAGATTTATCACTACTCGAACGAGGGGGTGCTCAGTTGGTACGATTTTGCCAAAGAGATCATGAAGATGGCGAAGCTGGAGTGCAAGATCAATCCGATAGAGACAAAGTCCTATCCAACGCCGGCCAAAAGGCCATACTACTCTTTGTTGAATAAAGCAAAGATAAAAGAGACTTTCAATCTGGAAATCCCATACTGGAAAGATGGATTGGATACCTGTCTCAGAACAATGGGTGAAAGAAAATGAAAAGTATTTTGTTAACTGGAACAGCAGGCTTCATCGGTTCGAATTTCGCACCGTATTTTTTGGAAAAATATCCGGAGTACAATTTGATCAATCTCGATTTGTTGACCTATGCCGGAGATCTCGCGAACCTGAAGGAATGTGAAGAAAACCCGAGATACAAATTTATCAAAGGGGATATCTGCAACCGTGAGCTGGTCGAGTTTATTTTCAAAGAGTATGACATTCGCGGGATAATACACTTTGCGGCGGAATCCCATGTGGATAATTCCATTAAGAACCCGGGAGTATTTGTAGAGACCAACGTGAACGGTACTTTTACTCTGCTGGATGTGGCGCAAAAACACTGGATGGAAAAACCTTTTAGCTACAAAAAGGGGTACAAAGGGTGCAGGTTTCACCATATCTCCACCGATGAGGTATACGGTACCCTGAATGAGACGGATCTTTTCACCGAAAAGACGCCGTATGCCCCAAATTCCCCTTATTCCGCCTCAAAAGCTTCAAGCGATATGATCGTACGTTCCTATCAGGAGACCTATGGCCTGAATACGGTGATCACGAATTGTTCGAATAATTATGGCCCGAAGCAGCATGATGAGAAGTTGATACCGACGATCATCAGAAAGGCGTTGGCAGGAGAGAGTATTCCTATTTACGGAGATGGAAAAAATATACGGGATTGGCTTTATGTCCTGGATCATTGCAAGGGGATCGATCTGGTCTATCATGCAGGGAAAGAGGGAAATGTCTATAATATTGGAGGACGTAACGAGCGTACCAACCTGCAGATCGCAGATACGATCTGCAGGATACTGGATGAGAAAATACCTGTAAAAAAGAGTTATAAAGAGCTGGTCACTTTTGTGGAAGACAGGGCAGGACATGATAGACGCTATGCTATCGATGCGACCAAAATTGAAAATGAGCTGGGTTGGAAAGCGGACGAGAACTTTGATACGGGGATCATCAAGACTGTTGACTGGTACTTGAAAAAGTACAACGTCCAATAA

Protein sequences of DBSCAN-SWA_2

>NZ_CP011308|295986:302819|298735_299485_+|WP_046550313.1|DBSCAN-SWA
MLDKIDLNDIQKIAQDAGNTIMEIYNRDFSIEYKDDKSPLTEADTASHEVIMEGLEKYGIPVMSEEGKTITYDERKGWEYYWCVDPIDGTKEFIKKNGEFTVNIALIHKDTPVLGVVYAPALGDMYKAKKGEGAFKNDQKLPLCSNPDQKEKMSVVASKSHLSEETQAFIDALDTRNIEQVSKGSSLKLCMVAEGEADIYPRLAPTMEWDTAAADAVVRESGKMTCQFENDRPVVYNKENLLNPWFVVK
>NZ_CP011308|295986:302819|299489_300362_+|WP_046550314.1|DBSCAN-SWA
MKGIILAGGSGTRLYPITKGVSKQLVPIYDKPMIYYPLSVLMLAGIKEVLIISTPQDLPRFEELLGDGSNIGMQFSYMAQPSPDGLAQAFLLGESFIGDDNVCLILGDNIFYGHALTELLKKSIANAEIEDKATVYGYYVSDPERYGVAEFDTRGNVVSLEEKPKYPKSNYAVVGLYFYPNDVVKKAKEVNPSDRGELEITTLNQMYLEEERLRVKLMGRGYAWLDTGTHESLLEASQFIQTIEKRQSLKVACIEEIAYEMGYISKEQLLTLAEPLKKSNYGQYLIQRAQ
>NZ_CP011308|295986:302819|301805_302819_+|WP_046550317.1|DBSCAN-SWA
MKSILLTGTAGFIGSNFAPYFLEKYPEYNLINLDLLTYAGDLANLKECEENPRYKFIKGDICNRELVEFIFKEYDIRGIIHFAAESHVDNSIKNPGVFVETNVNGTFTLLDVAQKHWMEKPFSYKKGYKGCRFHHISTDEVYGTLNETDLFTEKTPYAPNSPYSASKASSDMIVRSYQETYGLNTVITNCSNNYGPKQHDEKLIPTIIRKALAGESIPIYGDGKNIRDWLYVLDHCKGIDLVYHAGKEGNVYNIGGRNERTNLQIADTICRILDEKIPVKKSYKELVTFVEDRAGHDRRYAIDATKIENELGWKADENFDTGIIKTVDWYLKKYNVQ
>NZ_CP011308|295986:302819|300945_301809_+|WP_046550316.1|DBSCAN-SWA
MPNILVTGSRGQLGSELRELVNNNAIFHFTDRSVLDITDQDAIKHFCLEKDIEVIINCAAYTAVDKAEEDEENADRINHLAVKYLAQIAKEREIRFVHISTDYVFDGTNFMPYVESNRTNPTSVYGRTKLAGEEAIRKINPDNTVIIRTSWVYSTYGSNFVKTMLRLGKERDTLGVIFDQVGTPTYARDLAQAILDIVPQIENKEVEIYHYSNEGVLSWYDFAKEIMKMAKLECKINPIETKSYPTPAKRPYYSLLNKAKIKETFNLEIPYWKDGLDTCLRTMGERK
>NZ_CP011308|295986:302819|297425_298151_+|WP_046550311.1|DBSCAN-SWA
MYRETNQRSIVKGISWRVVATTTTILIVYFFFDRLDLAIAAGLIETVLKVALYWGHEKIWQRIHWGKKKIDPFNLWFTGLPLSGKTTIADKVYTELEKLHIPIERIDSKDIRDLIPDIGYTREDRNRHMHRIGFLIQRLQKNSISTVATFVSPYTESRKAIREMVKNNIVIYVKADIETCKSRDYKGVYDRAMKGELKNFSGINDVYEEPQHAEITVDTNKLSADEAAEIIAKYVKKHYVK
>NZ_CP011308|295986:302819|298140_298746_+|WP_046550312.1|DBSCAN-SWA
MSNENIVWHDHHVTKEERAAIKTQKPCILWFTGLSGSGKSTVANAVESRLLALKKHTYLLDGDNIRMGLNRGLTFSDEDRVENIRRIGEVSKLFVDAGTIVLTAFISPFQKERDAVRALVEKDEFIEIFIDTPIAVCESRDPKGLYEKARKGEIPNFTGISSPYEAPAEAEIHVKTEDQTIAESAEQVIGYLKEKGYINAG
>NZ_CP011308|295986:302819|295986_297426_+|WP_046550310.1|DBSCAN-SWA
MSQENNKIAMDIEGYLKEHENKDMLRFLTCGSVDDGKSTLIGRMLYDSKMIFDDQLSAAEGESKKYGTTGEKIDMALLVDGLQSEREQGITIDVAYRFFATENRKFIIADTPGHEQYTRNMVTGASTADVAIILIDARKGILTQTRRHSFIVNLLGIEHVIVAINKMDLVDFSEEVYNDISKAYGVLADELGIKNTYYIPVSALEGDNVVDKSEKMPWYTGMPLLGLLDSMDISKEQTAENFRLPVQYVNRPNLDFRGFCGTIAAGEVKVGDEITVLPSGKTTKVKSIINAGDITEDNRTATTQFAYAPMAVTITTEDEVDISRGDMIVHTKSLPRVSNSLKVMLVWMDETPMEVGRSYDIKRATSVVSGAFEHINYKVDVNTYEREQVHSLGLNDIASCKMVLTQPIAADAYEMNRLTGSFIVVDRITNNTVGAGMIVGVSRREEDAAKLSEKEYTDAERALNQYIRENFPEWECKVV
>NZ_CP011308|295986:302819|300377_300953_+|WP_046550315.1|DBSCAN-SWA
MNFIRTEIEDVVIVEPAIHGDERGYFVETFRQDKLSEFLGYTIDFCQDNESKSSYGVLRGLHYQLPPHAQTKLVRVIQGRVLDVAVDIRKGSPTFGQHVAVELSGENKRQLLVPRGFAHAFIVLADDTIFAYKVDAYYSPECDRGISYADKDLGIEWPMPLEEIKLSEKDTRQPELYETDDLFEYGVNYYA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046550310.1|295986_297426_+	sulfate adenylyltransferase subunit CysN	A0A1V0SGC3	Hokovirus	4.7e-33	26.1
WP_046550311.1|297425_298151_+	adenylyl-sulfate kinase	NA	NA	NA	NA
WP_046550312.1|298140_298746_+	adenylyl-sulfate kinase	A0A2P1ELS9	Moumouvirus	4.4e-25	41.3
WP_046550313.1|298735_299485_+	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_046550314.1|299489_300362_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	4.4e-103	61.3
WP_046550315.1|300377_300953_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	6.2e-37	46.4
WP_046550316.1|300945_301809_+	dTDP-4-dehydrorhamnose reductase	A0A1D8EQE2	Escherichia_phage	7.9e-44	39.7
WP_046550317.1|301805_302819_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	9.8e-78	47.0

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP011308|497335:505560|DBSCAN-SWA
GTCAACTTTGTTCTTTGTACCACTGATACATCTTCTCTATGCCTTCCGTCAGGCCGATGCTGTGTTGCCATCCCAGTCCATGAAGCTTGGAAACATCTGTCAGCTTCTTCATGGTTCCGTCGGGTTTGTCCGTATTGAAATAGAGCTCCCCTTTGAAGCCGACGATCCCTTTAATGGTCTCTGCCAGTTCTTTGATGGAGATATCCACACCGGTACCGATATTGATGTGGGTGTTCCTGACCTCCTGGTTTTTGACTTCGGTGGGAGTACAGGTAGTGTTAGCGCCTTCAGAAACGCTGTAGGTATCTTTGAAGTCACGGTTCTCCATAAGGAAAACGCAGGCATCTGCCATATCTTCAGACCAGAGGAATTCCCGCATCGGTTTTCCGGAACCCCAGATCTCCACTCTGTTGCCGTCAACACCGAATTTTGCCAGATACTCTTTTGCCTCATCGATGCTTTCTGCCTTTAGGTCCTTGACCACTTCTTCCTCTTTGCCTTCGTTGAGAAGTTTCGCGCAGTGGATCTTTCTGATGAGTGCCGGAAGTACATGGGACTTCTCAAGATCGAAGTTGTCGTTGGGGCCGTAAAGGTTGGTCGGCATGACGGAGATATAGTTGGTTCCGTACTGCAGGTTGTAACTCTCACACATCTTGATACCCGCGATCTTGGCGATGGCATAAGGTTCGTTGGTGTACTCCAGCTCGCTTGTCAGCAGGTATTCCTCTTTCATAGGCTGAGGGCAGTTTTTGGGGTAGATGCAGGTGGACCCCAGGAACATCAGTTTCTTCACACCGTTAAGGTAACTCTGGTGGATGATGTTATTCTGGATCTGGAGGTTTTCATAAATGAAGTCGGCACGGTAGGTGTTGTTCGCCACAATACCGCCCACTTTCGCGGCTGCGAGAAAAACATAGTCTGGTTTTTCCGTCTCGAAGAATTCCTTGACGGCATTCTGGTCCAAGAGGTCCAGTTCACTGTGCGTCCTGCCTATGACATTGGTATAGCCCTTGGCTTTGAGGTTGTTGACAATGGCGGAGCCTACCAGTCCCCTGTGACCGGCAACGTAGATCTTGCTGTTTTTTTGCACTGTACTGCCTATTCGAAATAGTTCATGATGGTGTAACCGCCCTCTTTGAGGTACTGGTCTTTGGTCATCAGGTGGAGGTCTGACTTCATCATATCATTGACGAGCTCTTCGAGTTTGTATTCACGCTTCCAGCCGAGTTTCTGTTCCGCTTTTGTCGGATCACCGATAAGCAGGTCCACTTCGGTTGGACGGAAGTAGCGCGGATCAACGGCGACCACTGCTTTGCCTGCAAGCTCCTGGAGTCTTTGGACGTCAAGCCCGGCATTCTTCGCCTTTGTCTCATCGATGGACTTGACGATACCCACTTCATCGACACCTTCGCCTTTGAATTCCAGTTCGATACCCACATAACCAAACGCCATACGTACAAAGTCACGTACAGCCGTGGTGACACCTGTAGCGATGACCCAGTCTTCGGGTTCATCCGCCTGAAGGATCAGCCACATCATCTTCACGTAGTCTTTGGCATGTCCCCAGTCACGCTTGGCATCGAGATTACCCAGGTAGAGTTTGTCCTGAAGGCCCAGAGCGATCTTGGAAGCAGCCCTTGTGATCTTTCTGGTTACGAAGGTTTCACCACGTACGGGAGATTCATGGTTGAAGAGAATGCCGTTACAGGCAAACATGTCATACGCTTCACGGTAGTTGACCGTGATCCAGTAGGCATACATCTTTGCCACGGCATAAGGAGAACGCGGATAGAACGGTGTCGTCTCTGTCTGAGGAACTTCCTGTACTTTTCCATAAAGCTCTGAAGTGGATGCCTGGTAGATGCGTGTCTTCTCTGTAAGTCCAAGCAGTCTGACCGCTTCGAGGATACGAAGTGTTCCCGTTCCGTCCGCATTGGCCACGTATTCGGGTGTTTCGAACGAGACGGCTACGTGAGACATGGCGGCGAGGTTGTAGATCTCGTCTGGCTGGACTTCCTGGATGATACGCGTCAGGTTCATGGAATCCGTCATCTCGCCATAATGCAGGATGAAGTTCCTGTGCTCTACATGTGGGTCCTGATAGAGGTGGTCGATACGGTCCGTGTTAAAAAGAGATGCTCTTCTTTTGATACCATGTACAATATACCCTTTCTTTAAAAGGAATTCAGCCAGGTAGGACCCGTCCTGTCCAGTGACTCCGGTGATAAGTGCTACTTTTTGTTCTGCCATTTAATTCTCCATTCTTTTAAAATCATCAGCAAGACGAACGATATCATCTTCGCCCACATACTCGCCTACCTGCGCTTCGATCATTACCAGGTCGATCTTTCCTACGTTTTCCAGACGGTGTATTTCTCCCATAGGGATATAGGTCGATTCATTCGCACGTACGAGATACTCTTTGTTGCCACGTGTAACGGTGGCTGTACCTGAGACAACGATCCAGTGTTCAGAACGGTGGAAATGTTTCTGCAGAGAAAGGCGTTTACCCGGTTTGACCACGATACGTTTGACCTTGTATCCATTGGATTCATCCAGTATAGTATAGGTTCCCCAAGGTCTGTGTGCAGTGACATGGATGTTGGGCAGCTCGGAGTTACGCTCTTTAAGCTTTTTCACTACTTCCTTGACCTTCTGTGAGCTACCCTTTTGGGAGACCAGAAGCGCATCGGCGGTGTCAACGATGAGCAGGTCATCCACATCAATGGCGGCGACCAGCTTTTCAGAGAGGATGAGATTGTTGCTGGCCTGCTGTGTGATGATCTCTGAGTTCAGGGAAGAAGAAGCATTGCCGTTACTGTCCTGCGGCAGTTCCTCATATAGTGCGTCGAAACTTCCAAGATCGCTCCATGCAATGTCCGAAGGCACGACTTTGACACGGCTGCTCTGCTCCATCACCGCATAGTCGATGCTGTCTTCGGGGATGGCCATCATATCTTCATGGGATATACGGATCATGTCATCTTTCTTTGCCTGTCCATAAGCCTTTACCGATGCTTCGAAGATCTCCGGTGCGTAGCTTTGGAGTTCATCAAGGAACGTACCCGCCTTGAAACAGAACATCCCTGAGTTCCAGTAGTAGTTTCCTGCATCAAGATAGGACTGGGCGGTCTGTGCATCAGGCTTCTCCCTGAAGGAGCGGACATCTTCACCTTCTGCTTCAATATAACCAAACCCCGTTTCGGGATATTGTGGAGTGATACCGAAGGTAACGAGACTGCCCTGCACTGCCAGAGCTTTTGCTCTCTCTACAGCTTCCAGGTAGGCAACTTCATCCTTGATGAGATGATCGGAAGGTGTGACAAGGACTGTCTCTTCGGGGTCAAGCGCTAGACAGGCAAGCGCGATGGCCGGAGCTGTATTCCTCCCTACCGGCTCCAACAGGAATGTTAAATGTTGAATGTTTAATTTTGAATGATCGTCGTTATGTTCTTCTATCTGGTCTACTGCCAGAAAGTACTGTTCTGTGTTGGAGACAATGAACTGAGAGTCGCAGGCTTTCTGGTTACGCTCCACGGTCTTCTGGAAGAGGGACTCTTCTTCGAAGAGCTTGACGAACTGTTTGGGCATAAGCGTACGGCTGAGTGGCCACAGCCGGGTACCGCTGCCGCCGCATAATATGATATTAGTCATGTTTACCTTTATTGTAAAAATAATTCGTGGCTTTGACAAAACCGTCAACGGACCCGCAGTCAAAACGGTTGCCCTTGAATTTGTAGGCAATGACATTTCCCTGTTTGGCCTGTTCGAGCAGGGCATCGGTAATTTGTATCTCTCCGCCTTTTCCTGGCTTTGTTTCACGCAGGATGTCAAAGATATCCGGAGTCAAAATATATCTGCCTATGATAGCCATATTGGTCGGTGCATCTTTAGGGTCTGGTTTTTCTATCATGTCGGTGACCCTGTAGGTATCGTCCGTTCCATCTACCAGATTGCCTGCTATAACACCGTATTTGTCAGTTTTATCCATAGGAACCTCTTCAATCGCTATAACTGAACATTGATATTTTTCATAAATATTTACCATTTGTTTCAATATGGGATCGTCTCCATTGTTATGACAGAGGTCATCGGCCAGAATGACGGCAAAAGGTTCATCGCCTATGAGAGTCTCTCCTGTAAGGATGGCATGGCCCAGGCCTTTCATTTCAAGCTGTCTGGTATAGGAGAAGGTACATTGGGTAATAAGGGAACGAATTTCATTGAGGAGGGGTTCTTTGCTTGTACCTTTGACCTGATGCTCCAGCTCATAAGAGATGTCAAAATGGTCTTCTATGGCTCTCTTCCCCCGACCTGTGATAATAGCCATAGTATTGAGCCCCGCTTCAACGGCTTCCTCAACACCATATTGAATAAGAGGTTTAGTAAGGATGGGAAGCATTTCTTTGGGGGTAGCTTTGGTAGCAGGCAGGAAACGTGTACCGTAACCGGCTGCCGGAAATAGACATTTTTTGATCATTATTTCTCACTTTATTAATATTATAATAATTATAGCTAAAGCTGTATTATACAGTAATAATACAGCTATGCTTCCAACTTCTTCTTCAAAATGATCTTCCCCGCTTCAACTCCAGGCTGGTCGTAGGTATTGACATCTATGAGCTCTCCCACAAGAGAGGTGAGAAGTTCATAATAGAAGATAAGGGAACCAATGTTTTTTTCTGTTACGGAGGTGACGCTTATGGTGTCTAAAGGTATGTCTCCCTGATCCTGAAGTGCTTCTATGACTGAGTCGCACTGCATATTGATGAGTTTTGAGAAAGGTAATGAATTGAGTGTGTCGAGTGATTCCAAATGGGTAAGGGTGATATCTGGAATAGTAATGTTGTCATGAAAATCTTCGATCTTGATAAAAGTGACGGATTTATCTCTGGTCCCTTCCATGATGAGCTGGAGGAAGGAGTGCTGGTCTTTTGGGCCGATGAGCCCGATAGGGGTCAGCCCGACATGAAAAGCGGAGTGCCGTTGGTGTTTCCCGAGACTTTCACCCCAGAGCTGTACATACCATTCACAGAAGTATTTGAGTGTTTCGGAGTAGGCAAAGATACAGTTGATATGGTACTGTGCATGGTGTTTGGCATAAAAAGCGGCTTTTTTGAGCAGGGTGTCTTTCATGTAGCCATTGTTGAAAAAACTCTCTTTAATACTTTTTGCACCCAGTAAAAGTGCTTCAATATCGATGCCGCACAGAGCCAGAGGAACCAAACCTACAGCAGAGAGAACAGAGAACCTTCCGCCTACATTGTCAGGCAGGTGCAGCACAGAAGCTTTTATCTCCTTGGCATACTGTTCAAGCGGTGATCCGGGATCGGTAATGAAAGTGTAGGCTGAGGCATTGTTTTGGAGAGAATAGAGGTACTTGTAGATGGAGAAAGTCTCAATAGTTGTACCTGATTTGGAAATGACAAGAAAATGCGTCTTTTCAAGGTCGATCTTTGAAAGAAGTGTTGTGATATTGATAGGGTCGGTACTTTCAAAAAAGCATAGTCTTCTTTTCAGTTCTTTGGTGGGTTTAATGAACTCATAAACAGCTTTTGCCCCCAAAGAGCTGCCGCCGATTCCGATGACGGCAATTGTTTCTATGTCATCCGGGATAGTATTGCAATATTCCAATAGAGGTGTAATATCCTGATTTGGAAGGTTGTAATAACCTATGTAGTTCTGTTCTTGACAAAGTGCCTCGAAAGCATTTTCCTGAACAGCTTTGTCGGAAGGGTTAAAATAGAGTTTATTGATCACAATGAACTCTTTGCCGTTTTAATGAGCTGATTGACTTTGAGCTCATACGCTTTTGCCAGTGCGGCATCTGTCGATTCGAAACGTGTCACCAGTACAGGAGTGGTGTTGCTGGCCCTGACAAGTCCCCAGCCTTTTTCAAAGTTGATACGGACACCGTCCACATCAATGATGTTGAGGATAGTCGGGAAATCTTTCGGAGGGTTTTTGAGCAGTTCTTTGACTTGGTCTATGATGGCAAATTTTTCCTCTTCCGTAGTTTCCACCTTCAACTCTTCAGTGGAGAAGACTTGAGGCAGGGCTTCTATCTCTTTGTCAAGGTCAATGCCGTCTGCAATAAGTTCAAGCATACGCAACGTGGCATAGATGGCATCGTCGTAGCCGAAGTAGCGGTGTTTGAAGAAAATGTGGCCTGAAACTTCGCAGGCAAGGTCCGCATTCGCCTCTTTCATCTTGACCTTGAGGTTGGAGTGGCCTGTTTTGTACATGATGGCCTTGGCACCGCGTTTTTCAAGTTCGTCATACATGACCTGTGAACATTTGACTTCTCCGATGACAGTTGGATTTTCCATCTTCATGGCATACAACAGTGCCATCTGGTCACCCTTGATGTTGTGTTTATGTGTCAGTACTGCGATGCGGTCGGCATCACCGTCATAGGCAAAAGCAATGTCCCCTTCTTTTTCCAGAGCAGTTTTGACATCGGCAAGATTCTTCTCTACGGAGGGGTCAGGATGATGGTTGGGAAAGGTACCGTCGGGCTCACAGTAAAGTCCGGTATAGTTGAGCTCCAGAGCATCGAATATATCTGTAATGACCGTATCTGCCACACCGTTACCGCAGTCGATGACGATCTTCTTGTCCAGGCCCTTTAGATGGCTGAACTCTTTGACCATAAAGTTGATGTAAGGGGTTTTGACATTGATATCGATCTTCTTAGTATCATCAGGGATAATCCTCTCCTGATCGGTGATGATGGCATCTCCGAGTGCGTAAATATCCTTACCAAAGAAAGGTGTTTTGTCAAGGGTGATCTTGAAACCATTGTATTCGGAAGGATTGTGGGAACCGGTGATCATAATGGAAGCCGTAGGGTGTTGTGCCCCCACAATACCATCTAAAGATGTGGGATGAAGATCTTCGATCTTTTGATAGTTGCTAAAATAATTTACAGGTGTGGCTACCATACCCATGTCGAGGACGGTACATCCGGCTGCATTGAGTCCTGAAGTAAGGTAGTCTCTCAAAATGGGGGAGTGAGAACGTGCATCATAGCCGATGGAGACCACCTTGCCTTTGCCGATCTTTTTTCCCAGGTGATAGCCTATCAGTTTGACAGACTGTTCATTGAGCTCTTTATTGTAAATACCTCTGATATCGTATTCTCGGAAAATGGAAGAGGGGATGGACATGTTGTTCCTTACAAAATATTTTGATAATTATAACAAAAACGGGTTAAGAACTATATCCGTTTGGATTGTTTGACTGCCATCTCCAGGAATCTTTACACATCGTTTCTATCCCCTTTTTTGCTTCCCAGCCTAAAATCTTTTTTGCATAGGAAGGGTCTGCATAGCATTTGGCAATATCTCCGGCTCTGCGTGGTGCGATGCAGTAGGAGATTTCTCTGCCTGAAGCTTTTTCAAATGCTTTGACCATATCGAGAACGGAATATCCTGTGCCTGTACCGAGGTTGATGGCCATAACCTTATTGAAGTCTTTGAGCCTTTTCAGGGCCTTTACGTGTCCGTCGGCCAGGTCCATGACATGGATGTAGTCGCGCACACCTGTCCCGTCATGCGTTTCGTAGTTATCGCCAAAGACGCTGAGGCAGGAGCGTTTGCCCACAGCCGTCTGGGTAATGAAGGGCATGAGGTTGTTGGGGATGTCGCTGGGGTCTTCGCCTATAGTTCCCGAGGGGTGTGCACCTACGGGGTTGAAGTAGCGCAGCAGAACGATCTTCCATTCACTGTCCGAGGTATGGAGGTCACGGAGTATCTCTTCGATGAAAAGTTTGCTTCTGCCGTAGGGATTGGTCGCCGATGTAGGGAACTCTTCTGTGATGGGAGTACTTGCCGGATCGCCGTATACTGTTGCAGAAGAGCTGAAAATGATAGATTTGCATCCGTGCTCCTCCATCACTTCACAGAGTGTGACAGTACCATGGACATTGTTATCATAGTACCTGAGGGGCTGCTCAACGGATTCGCCTACAGCTTTGAGCCCTGCAAAATGGATGACCGCATTGATCTTATGGTCAGTAAAGACGGTGTGAAGCGCTTCCTTGTTCCTGATGTCGCCTTCAATAGTCGTGATCGTCCGGCCGACGATCTTTTCAACCCTGCGGATACTTTCTCTTGAAGAATTGCAGAAATTGTCAAAGACTACCACCTCATAGCCTGCTTCAACAAGCAGGATGACAGTATGGGAACCGATATATCCGGCACCGCCGGTGACGAGAACTTTCAT

Protein sequences of DBSCAN-SWA_3

>NZ_CP011308|497335:505560|498432_499584_-|WP_046550466.1|DBSCAN-SWA
MAEQKVALITGVTGQDGSYLAEFLLKKGYIVHGIKRRASLFNTDRIDHLYQDPHVEHRNFILHYGEMTDSMNLTRIIQEVQPDEIYNLAAMSHVAVSFETPEYVANADGTGTLRILEAVRLLGLTEKTRIYQASTSELYGKVQEVPQTETTPFYPRSPYAVAKMYAYWITVNYREAYDMFACNGILFNHESPVRGETFVTRKITRAASKIALGLQDKLYLGNLDAKRDWGHAKDYVKMMWLILQADEPEDWVIATGVTTAVRDFVRMAFGYVGIELEFKGEGVDEVGIVKSIDETKAKNAGLDVQRLQELAGKAVVAVDPRYFRPTEVDLLIGDPTKAEQKLGWKREYKLEELVNDMMKSDLHLMTKDQYLKEGGYTIMNYFE
>NZ_CP011308|497335:505560|504546_505560_-|WP_046550471.1|DBSCAN-SWA
MKVLVTGGAGYIGSHTVILLVEAGYEVVVFDNFCNSSRESIRRVEKIVGRTITTIEGDIRNKEALHTVFTDHKINAVIHFAGLKAVGESVEQPLRYYDNNVHGTVTLCEVMEEHGCKSIIFSSSATVYGDPASTPITEEFPTSATNPYGRSKLFIEEILRDLHTSDSEWKIVLLRYFNPVGAHPSGTIGEDPSDIPNNLMPFITQTAVGKRSCLSVFGDNYETHDGTGVRDYIHVMDLADGHVKALKRLKDFNKVMAINLGTGTGYSVLDMVKAFEKASGREISYCIAPRRAGDIAKCYADPSYAKKILGWEAKKGIETMCKDSWRWQSNNPNGYSS
>NZ_CP011308|497335:505560|503090_504503_-|WP_046550470.1|DBSCAN-SWA
MSIPSSIFREYDIRGIYNKELNEQSVKLIGYHLGKKIGKGKVVSIGYDARSHSPILRDYLTSGLNAAGCTVLDMGMVATPVNYFSNYQKIEDLHPTSLDGIVGAQHPTASIMITGSHNPSEYNGFKITLDKTPFFGKDIYALGDAIITDQERIIPDDTKKIDINVKTPYINFMVKEFSHLKGLDKKIVIDCGNGVADTVITDIFDALELNYTGLYCEPDGTFPNHHPDPSVEKNLADVKTALEKEGDIAFAYDGDADRIAVLTHKHNIKGDQMALLYAMKMENPTVIGEVKCSQVMYDELEKRGAKAIMYKTGHSNLKVKMKEANADLACEVSGHIFFKHRYFGYDDAIYATLRMLELIADGIDLDKEIEALPQVFSTEELKVETTEEEKFAIIDQVKELLKNPPKDFPTILNIIDVDGVRINFEKGWGLVRASNTTPVLVTRFESTDAALAKAYELKVNQLIKTAKSSL
>NZ_CP011308|497335:505560|500980_501814_-|WP_046550468.1|DBSCAN-SWA
MIKKCLFPAAGYGTRFLPATKATPKEMLPILTKPLIQYGVEEAVEAGLNTMAIITGRGKRAIEDHFDISYELEHQVKGTSKEPLLNEIRSLITQCTFSYTRQLEMKGLGHAILTGETLIGDEPFAVILADDLCHNNGDDPILKQMVNIYEKYQCSVIAIEEVPMDKTDKYGVIAGNLVDGTDDTYRVTDMIEKPDPKDAPTNMAIIGRYILTPDIFDILRETKPGKGGEIQITDALLEQAKQGNVIAYKFKGNRFDCGSVDGFVKATNYFYNKGKHD
>NZ_CP011308|497335:505560|497335_498424_-|WP_046550465.1|DBSCAN-SWA
MQKNSKIYVAGHRGLVGSAIVNNLKAKGYTNVIGRTHSELDLLDQNAVKEFFETEKPDYVFLAAAKVGGIVANNTYRADFIYENLQIQNNIIHQSYLNGVKKLMFLGSTCIYPKNCPQPMKEEYLLTSELEYTNEPYAIAKIAGIKMCESYNLQYGTNYISVMPTNLYGPNDNFDLEKSHVLPALIRKIHCAKLLNEGKEEEVVKDLKAESIDEAKEYLAKFGVDGNRVEIWGSGKPMREFLWSEDMADACVFLMENRDFKDTYSVSEGANTTCTPTEVKNQEVRNTHINIGTGVDISIKELAETIKGIVGFKGELYFNTDKPDGTMKKLTDVSKLHGLGWQHSIGLTEGIEKMYQWYKEQS
>NZ_CP011308|497335:505560|499584_500988_-|WP_046550467.1|DBSCAN-SWA
MTNIILCGGSGTRLWPLSRTLMPKQFVKLFEEESLFQKTVERNQKACDSQFIVSNTEQYFLAVDQIEEHNDDHSKLNIQHLTFLLEPVGRNTAPAIALACLALDPEETVLVTPSDHLIKDEVAYLEAVERAKALAVQGSLVTFGITPQYPETGFGYIEAEGEDVRSFREKPDAQTAQSYLDAGNYYWNSGMFCFKAGTFLDELQSYAPEIFEASVKAYGQAKKDDMIRISHEDMMAIPEDSIDYAVMEQSSRVKVVPSDIAWSDLGSFDALYEELPQDSNGNASSSLNSEIITQQASNNLILSEKLVAAIDVDDLLIVDTADALLVSQKGSSQKVKEVVKKLKERNSELPNIHVTAHRPWGTYTILDESNGYKVKRIVVKPGKRLSLQKHFHRSEHWIVVSGTATVTRGNKEYLVRANESTYIPMGEIHRLENVGKIDLVMIEAQVGEYVGEDDIVRLADDFKRMEN
>NZ_CP011308|497335:505560|501879_503094_-|WP_046550469.1|DBSCAN-SWA
MINKLYFNPSDKAVQENAFEALCQEQNYIGYYNLPNQDITPLLEYCNTIPDDIETIAVIGIGGSSLGAKAVYEFIKPTKELKRRLCFFESTDPINITTLLSKIDLEKTHFLVISKSGTTIETFSIYKYLYSLQNNASAYTFITDPGSPLEQYAKEIKASVLHLPDNVGGRFSVLSAVGLVPLALCGIDIEALLLGAKSIKESFFNNGYMKDTLLKKAAFYAKHHAQYHINCIFAYSETLKYFCEWYVQLWGESLGKHQRHSAFHVGLTPIGLIGPKDQHSFLQLIMEGTRDKSVTFIKIEDFHDNITIPDITLTHLESLDTLNSLPFSKLINMQCDSVIEALQDQGDIPLDTISVTSVTEKNIGSLIFYYELLTSLVGELIDVNTYDQPGVEAGKIILKKKLEA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046550465.1|497335_498424_-	GDP-L-fucose synthase	M4R1H4	Synechococcus_phage	1.4e-90	49.9
WP_046550466.1|498432_499584_-	GDP-mannose 4,6-dehydratase	M1HVG7	Acanthocystis_turfacea_Chlorella_virus	1.6e-124	60.7
WP_046550467.1|499584_500988_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	4.8e-59	32.8
WP_046550468.1|500980_501814_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.6e-68	49.2
WP_046550469.1|501879_503094_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_046550470.1|503090_504503_-	phosphomannomutase/phosphoglucomutase	A0A127AWJ1	Bacillus_phage	4.0e-53	32.3
WP_046550471.1|504546_505560_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	3.2e-81	46.2