CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007537	Streptococcus pyogenes strain AP1 chromosome, complete genome	6 crisprs	DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,csn2,cas9,csm6,DinG,csa3	3	4	9	9

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007537_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007537_1

598462-598756

TypeI

I-C

Consensus_repeat	Method
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	PILER-CR
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CRT

4 spacers

cas2,cas1,cas4,cas7,cas8c,cas5

The CRISPR arrays of NZ_CP007537_1

>merge|NZ_CP007537|1|598462-598756|PILER-CR,CRISPRCasFinder,CRT
GTCTCACCCTTCATGGGTGAGTGGATTGAAATAAAAAGCATATCACGAAAATCACCAATTACATCAGGTCTCACCCTTCATGGGTGAGTGGATTGAAATAAGTCATTTTCTGCTTCTGCTAGGTTTGCTTTAGTCTCACCCTTCATGGGTGAGTGGATTGAAATTTTTTACTTTGATTACATCCCGCAATGTCACAGCGTCTCACCCTTCATGGGTGAGTGGATTGAAATTGTCCGCATACCTTGATTTGAGCGAGTAAACTCGTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>NZ_CP007537|1|1|598462-598756|PILER-CR
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAAAAGCATATCACGAAAATCACCAATTACATCAG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAGTCATTTTCTGCTTCTGCTAGGTTTGCTTTA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTTTTACTTTGATTACATCCCGCAATGTCACAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TGTCCGCATACCTTGATTTGAGCGAGTAAACTC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>NZ_CP007537|1|1|598462-598756|CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAAAAGCATATCACGAAAATCACCAATTACATCAG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAGTCATTTTCTGCTTCTGCTAGGTTTGCTTTA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTTTTACTTTGATTACATCCCGCAATGTCACAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TGTCCGCATACCTTGATTTGAGCGAGTAAACTC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>NZ_CP007537|1|1|598462-598756|CRT
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAAAAGCATATCACGAAAATCACCAATTACATCAG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAGTCATTTTCTGCTTCTGCTAGGTTTGCTTTA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTTTTACTTTGATTACATCCCGCAATGTCACAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TGTCCGCATACCTTGATTTGAGCGAGTAAACTC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007537.1\|WP_010922509.1\|596983_598009_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP007537.1\|WP_011285642.1\|605134_605851_+\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
NZ_CP007537.1\|WP_002983795.1\|606631_607312_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_CP007537.1\|WP_002989056.1\|606016_606490_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_CP007537.1\|WP_010922508.1\|600304_601411_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_CP007537.1\|WP_002989022.1\|586927_587491_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379082
NZ_CP007537.1\|WP_010922510.1\|595462_596311_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP007537.1\|WP_003060901.1\|596312_596987_+\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
NZ_CP007537.1\|WP_002983803.1\|607585_608821_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
NZ_CP007537.1\|WP_002983778.1\|599638_600262_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP007537.1\|WP_010922507.1\|601498_602239_+\|response-regulator	unknown	unknown	gnl\|CDD\|227095
NZ_CP007537.1\|WP_002983750.1\|585659_585914_+\|DUF1912-family-protein	unknown	unknown	gnl\|CDD\|286073
NZ_CP007537.1\|WP_029714133.1\|587492_590141_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP007537.1\|WP_002989018.1\|585931_586327_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_CP007537.1\|WP_010922506.1\|604041_605121_+\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_CP007537.1\|WP_010922512.1\|592834_593563_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP007537.1\|WP_010922511.1\|593562_595458_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187773
NZ_CP007537.1\|WP_002983776.1\|598915_599626_+\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856
NZ_CP007537.1\|WP_002989044.1\|598019_598313_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_CP007537.1\|WP_011285644.1\|602235_603969_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519

Protein	Function_ID	Function_description	E-value
NZ_CP007537.1\|WP_010922509.1\|596983_598009_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP007537.1\|WP_011285642.1\|605134_605851_+\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	7.09856e-107
NZ_CP007537.1\|WP_002983795.1\|606631_607312_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.46736e-40
NZ_CP007537.1\|WP_002989056.1\|606016_606490_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.68589e-66
NZ_CP007537.1\|WP_010922508.1\|600304_601411_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	3.93012e-163
NZ_CP007537.1\|WP_002989022.1\|586927_587491_+\|AAA-family-ATPase	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	0.00400512
NZ_CP007537.1\|WP_010922510.1\|595462_596311_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	9.90819e-161
NZ_CP007537.1\|WP_003060901.1\|596312_596987_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	1.18604e-43
NZ_CP007537.1\|WP_002983803.1\|607585_608821_+\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_CP007537.1\|WP_002983778.1\|599638_600262_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.89498e-35
NZ_CP007537.1\|WP_010922507.1\|601498_602239_+\|response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	7.39476e-84
NZ_CP007537.1\|WP_002983750.1\|585659_585914_+\|DUF1912-family-protein	gnl\|CDD\|286073	pfam08930, DUF1912, Domain of unknown function (DUF1912). This domain has no known function. It is found in various Streptococcal proteins.	3.74168e-47
NZ_CP007537.1\|WP_029714133.1\|587492_590141_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP007537.1\|WP_002989018.1\|585931_586327_+\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	0.000151325
NZ_CP007537.1\|WP_010922506.1\|604041_605121_+\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	3.06295e-36
NZ_CP007537.1\|WP_010922512.1\|592834_593563_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.32713e-117
NZ_CP007537.1\|WP_010922511.1\|593562_595458_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187773	cd09642, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csd1 family.	0
NZ_CP007537.1\|WP_002983776.1\|598915_599626_+\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	1.97047e-42
NZ_CP007537.1\|WP_002989044.1\|598019_598313_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.60225e-34
NZ_CP007537.1\|WP_011285644.1\|602235_603969_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.09335e-64

>NZ_CP007537.1|WP_002989044.1|598019_598313_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>NZ_CP007537.1|WP_010922509.1|596983_598009_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSSALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>NZ_CP007537.1|WP_003060901.1|596312_596987_+|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMDL
>NZ_CP007537.1|WP_010922510.1|595462_596311_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTLEILEGL
>NZ_CP007537.1|WP_010922511.1|593562_595458_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRNNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMGQIQYDSFHKQLNNWIDYCEEGDVKKFLTFVQQFILKPEFLTLILDSLIGPDYQHNQLKVTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGICNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLMLKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITLATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKWQETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>NZ_CP007537.1|WP_010922512.1|592834_593563_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>NZ_CP007537.1|WP_029714133.1|587492_590141_+|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLADGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDDWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEDAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFNSNINYIKCFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMKKIKS
>NZ_CP007537.1|WP_002989022.1|586927_587491_+|AAA-family-ATPase
MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPWSQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTQLTAAETAQLIIQKMTHIKEN
>NZ_CP007537.1|WP_002989018.1|585931_586327_+|hypothetical-protein
MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTISAGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKEWTEKDLLALKGIGPATVKKLVENGASFKK
>NZ_CP007537.1|WP_002983750.1|585659_585914_+|DUF1912-family-protein
MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDAFIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY
>NZ_CP007537.1|WP_002983776.1|598915_599626_+|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>NZ_CP007537.1|WP_002983778.1|599638_600262_+|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDKMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>NZ_CP007537.1|WP_010922508.1|600304_601411_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKEKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>NZ_CP007537.1|WP_010922507.1|601498_602239_+|response-regulator
MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>NZ_CP007537.1|WP_011285644.1|602235_603969_+|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSSKKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQIFWSFLGTGLLACLICGFATVLVLRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
>NZ_CP007537.1|WP_010922506.1|604041_605121_+|MmcQ/YjbR-family-DNA-binding-protein
MSLATDYFSRQTPIVEKLMAYGFEKRDNGYFYNERFMEGEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEATPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKKHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>NZ_CP007537.1|WP_011285642.1|605134_605851_+|B3/4-domain-containing-protein
MVEFVADQSFWELFPGAKLGVVLLKDVQNQAESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPLVDIYNAASLRFGLPAGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHAITSVHVLDKDNPHVPLFTEN
>NZ_CP007537.1|WP_002989056.1|606016_606490_-|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>NZ_CP007537.1|WP_002983795.1|606631_607312_+|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>NZ_CP007537.1|WP_002983803.1|607585_608821_+|arginine-deiminase
MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI

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Crispr_ID: NZ_CP007537_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007537_2

758811-758946

Orphan

Consensus_repeat	Method
GCCTTAGAAGCATTAGCGGATCAAACAGACGCTTTACAATCAGAAGAAGCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007537_2

>merge|NZ_CP007537|2|758811-758946|CRISPRCasFinder
GCCTTAGAAGCATTAGCGGATCAAACAGACGCTTTACAATCAGAAGAAGCTGCGGTTGTTAAAGCGGATAACGCTGCTAGTGACGCCTTAGAAGCATTGGCGGATCAAACAGACGCTTTACAATCAGAAGAAGCTG

>NZ_CP007537|2|2|758811-758946|CRISPRCasFinder
GCCTTAGAAGCATTAGCGGATCAAACAGACGCTTTACAATCAGAAGAAGCTG	CGGTTGTTAAAGCGGATAACGCTGCTAGTGAC
GCCTTAGAAGCATTGGCGGATCAAACAGACGCTTTACAATCAGAAGAAGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007537.1\|WP_010922404.1\|766685_768074_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_CP007537.1\|WP_010922408.1\|762134_763100_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP007537.1\|WP_002992607.1\|751306_751510_+\|DUF3272-domain-containing-protein	unknown	unknown	gnl\|CDD\|314526
NZ_CP007537.1\|WP_010922414.1\|749044_749542_+\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
NZ_CP007537.1\|WP_002984100.1\|761272_762133_+\|methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|180918
NZ_CP007537.1\|WP_002984078.1\|751484_752426_-\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	unknown	unknown	gnl\|CDD\|237010
NZ_CP007537.1\|WP_010922411.1\|752629_755008_+\|internalin-A	unknown	unknown	gnl\|CDD\|227223
NZ_CP007537.1\|WP_010922415.1\|747774_748038_+\|DUF1294-domain-containing-protein	unknown	unknown	gnl\|CDD\|225863
NZ_CP007537.1\|WP_002989260.1\|748090_748900_-\|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|225217
NZ_CP007537.1\|WP_002989295.1\|756914_758174_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|183779
NZ_CP007537.1\|WP_002984115.1\|768975_769377_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961
NZ_CP007537.1\|WP_002984095.1\|759422_759965_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP007537.1\|WP_010922413.1\|749541_751212_+\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
NZ_CP007537.1\|WP_010922406.1\|764486_764978_+\|shikimate-kinase	unknown	unknown	gnl\|CDD\|234654
NZ_CP007537.1\|WP_010922405.1\|765185_766637_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_CP007537.1\|WP_002989302.1\|759973_761257_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_CP007537.1\|WP_010922410.1\|755544_756741_+\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_CP007537.1\|WP_015055964.1\|763210_764494_+\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_CP007537.1\|WP_015055963.1\|769483_770968_-\|DUF1846-domain-containing-protein	unknown	unknown	gnl\|CDD\|184220
NZ_CP007537.1\|WP_002984060.1\|747068_747695_+\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492

Protein	Function_ID	Function_description	E-value
NZ_CP007537.1\|WP_010922404.1\|766685_768074_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	1.88929e-179
NZ_CP007537.1\|WP_010922408.1\|762134_763100_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	5.44284e-56
NZ_CP007537.1\|WP_002992607.1\|751306_751510_+\|DUF3272-domain-containing-protein	gnl\|CDD\|314526	pfam11676, DUF3272, Protein of unknown function (DUF3272). This family of proteins with unknown function appears to be restricted to Streptococcus.	1.60094e-22
NZ_CP007537.1\|WP_010922414.1\|749044_749542_+\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	8.27061e-83
NZ_CP007537.1\|WP_002984100.1\|761272_762133_+\|methionyl-aminopeptidase	gnl\|CDD\|180918	PRK07281, PRK07281, methionyl aminopeptidase.	0
NZ_CP007537.1\|WP_002984078.1\|751484_752426_-\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	9.76241e-144
NZ_CP007537.1\|WP_010922411.1\|752629_755008_+\|internalin-A	gnl\|CDD\|227223	COG4886, COG4886, Leucine-rich repeat (LRR) protein [Function unknown].	2.46185e-31
NZ_CP007537.1\|WP_010922415.1\|747774_748038_+\|DUF1294-domain-containing-protein	gnl\|CDD\|225863	COG3326, COG3326, Predicted membrane protein [Function unknown].	9.26867e-29
NZ_CP007537.1\|WP_002989260.1\|748090_748900_-\|PrsW-family-intramembrane-metalloprotease	gnl\|CDD\|225217	COG2339, prsW, Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones].	2.0574e-58
NZ_CP007537.1\|WP_002989295.1\|756914_758174_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|183779	PRK12830, PRK12830, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed.	0
NZ_CP007537.1\|WP_002984115.1\|768975_769377_+\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	1.21804e-24
NZ_CP007537.1\|WP_002984095.1\|759422_759965_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.44756e-30
NZ_CP007537.1\|WP_010922413.1\|749541_751212_+\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_CP007537.1\|WP_010922406.1\|764486_764978_+\|shikimate-kinase	gnl\|CDD\|234654	PRK00131, aroK, shikimate kinase; Reviewed.	1.70335e-63
NZ_CP007537.1\|WP_010922405.1\|765185_766637_+\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	2.05459e-64
NZ_CP007537.1\|WP_002989302.1\|759973_761257_+\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_CP007537.1\|WP_010922410.1\|755544_756741_+\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NZ_CP007537.1\|WP_015055964.1\|763210_764494_+\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_CP007537.1\|WP_015055963.1\|769483_770968_-\|DUF1846-domain-containing-protein	gnl\|CDD\|184220	PRK13663, PRK13663, hypothetical protein; Provisional.	0
NZ_CP007537.1\|WP_002984060.1\|747068_747695_+\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	8.03786e-135

>NZ_CP007537.1|WP_002989295.1|756914_758174_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYMDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGYASIIAKLTALGADIQLIED
>NZ_CP007537.1|WP_010922410.1|755544_756741_+|methionine-adenosyltransferase
MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEAFESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAGLVTKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVEAVKTVL
>NZ_CP007537.1|WP_010922411.1|752629_755008_+|internalin-A
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGYTVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAHVADQYDPAKKAEKPAETHQTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNMMKEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNISLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD
>NZ_CP007537.1|WP_002984078.1|751484_752426_-|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor
MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQGIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPRLYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISRLTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIAQKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEKRAIAIDLTDQGHLIVQFENGDLQTLRSGEISLSSWEN
>NZ_CP007537.1|WP_002992607.1|751306_751510_+|DUF3272-domain-containing-protein
MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLRRVHTINQLTKTILKTANSPKKKD
>NZ_CP007537.1|WP_010922413.1|749541_751212_+|DNA-polymerase-III-subunit-gamma/tau
MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSGPRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDEIRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHKIPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALSILDQALSLSPDNQVAIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGKSMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIKKGTHPRIYAEMMTIQLAQKEQILSQVNLSGELISEIETLKNELAQLKQQLSQLQSRPDSLARSDKTKPKTTSYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQDRALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVPRTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD
>NZ_CP007537.1|WP_010922414.1|749044_749542_+|GAF-domain-containing-protein
MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPNSVFTGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYISCDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNMFGVKN
>NZ_CP007537.1|WP_002989260.1|748090_748900_-|PrsW-family-intramembrane-metalloprotease
MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALILTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWSYIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQLTEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQIFWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF
>NZ_CP007537.1|WP_010922415.1|747774_748038_+|DUF1294-domain-containing-protein
MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERKLLVITVLFGGFGALLAAKKYHHKTRKWYFVITCYTSILLTLLVTYIFMK
>NZ_CP007537.1|WP_002984060.1|747068_747695_+|uridine-kinase
MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV
>NZ_CP007537.1|WP_002984095.1|759422_759965_+|GNAT-family-N-acetyltransferase
MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYVFPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFLNYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKGSDRNTHKICIYKMYQLTNDR
>NZ_CP007537.1|WP_002989302.1|759973_761257_+|CBS-domain-containing-protein
MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAENRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGAMTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPVMVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKKTRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMIFEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVVVEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKIYPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN
>NZ_CP007537.1|WP_002984100.1|761272_762133_+|methionyl-aminopeptidase
MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYVRRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLSEPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEAMYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQGEERTY
>NZ_CP007537.1|WP_010922408.1|762134_763100_+|YihY/virulence-factor-BrkB-family-protein
MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLILTAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVATLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSIFSKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILPGTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIFNATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD
>NZ_CP007537.1|WP_015055964.1|763210_764494_+|3-phosphoshikimate-1-carboxyvinyltransferase
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLNAPCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITYTLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSNMKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAIAALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD
>NZ_CP007537.1|WP_010922406.1|764486_764978_+|shikimate-kinase
MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFEQHGEIAFRTIESQVLKDLLFANDNSIIVTGGGVVVLQENRQLLRKNHQHNILLVASFETLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANIIEGY
>NZ_CP007537.1|WP_010922405.1|765185_766637_+|LCP-family-protein
MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEIGRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKEDRYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNILGLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILILGSDQRVTQGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGEQEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVAVDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVMSAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPENGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR
>NZ_CP007537.1|WP_010922404.1|766685_768074_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVDNALPEEVIDMRVLKVNKNSGFGKVEAYHYLSSARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTITDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEVIEAAVRDAQQNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQTHHVECVVLLIKE
>NZ_CP007537.1|WP_002984115.1|768975_769377_+|PaaI-family-thioesterase
MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYGNAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTTQVVDVTIHNQTGALLTKTSLTMFVTGRRHNG
>NZ_CP007537.1|WP_015055963.1|769483_770968_-|DUF1846-domain-containing-protein
MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHAARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKFNTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMGKNNYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYASPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMNDIGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTLAKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKELGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK

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Crispr_ID: NZ_CP007537_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007537_3

864821-864921

Orphan

Consensus_repeat	Method
TATAATTAGACTATACCAATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007537_3

>merge|NZ_CP007537|3|864821-864921|CRISPRCasFinder
TATAATTAGACTATACCAATTTTATGTTTGACAAGACATTGTGGATATTATATACTGTAAACATAATGTTTTTATCGGTATAATTAGACTATACCAATTAT

>NZ_CP007537|3|3|864821-864921|CRISPRCasFinder
TATAATTAGACTATACCAATTTT	ATGTTTGACAAGACATTGTGGATATTATATACTGTAAACATAATGTTTTTATCGG
TATAATTAGACTATACCAATTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007537.1\|WP_002989626.1\|866982_867318_+\|alkylphosphonate-utilization-protein	unknown	unknown	gnl\|CDD\|225380
NZ_CP007537.1\|WP_010922374.1\|864972_866787_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP007537.1\|WP_002992417.1\|867423_868065_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP007537.1\|WP_002989648.1\|874273_876592_+\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_CP007537.1\|WP_010922378.1\|856204_856990_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_010922375.1\|861443_862457_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_CP007537.1\|WP_011285556.1\|869925_870699_+\|CAMP-factor-pore-forming-toxin-Cfa	unknown	unknown	gnl\|CDD\|369335
NZ_CP007537.1\|WP_010922370.1\|871067_872303_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_CP007537.1\|WP_002984447.1\|862519_864022_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_CP007537.1\|WP_002984449.1\|864239_864797_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP007537.1\|WP_009880239.1\|853708_854464_-\|streptococcal-pyrogenic-exotoxin-SpeA	unknown	unknown	gnl\|CDD\|280949
NZ_CP007537.1\|WP_002984457.1\|868074_868704_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP007537.1\|WP_010922372.1\|868719_869556_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NZ_CP007537.1\|WP_011285555.1\|872422_873745_-\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NZ_CP007537.1\|WP_010922377.1\|857697_858069_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_CP007537.1\|WP_010922376.1\|858253_861364_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
NZ_CP007537.1\|WP_011285559.1\|854684_854873_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_002984437.1\|856999_857698_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP007537.1\|WP_011285558.1\|855463_856078_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP007537.1\|WP_002984469.1\|876955_877204_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170

Protein	Function_ID	Function_description	E-value
NZ_CP007537.1\|WP_002989626.1\|866982_867318_+\|alkylphosphonate-utilization-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	2.02984e-64
NZ_CP007537.1\|WP_002984449.1\|864239_864797_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38
NZ_CP007537.1\|WP_002992417.1\|867423_868065_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.99371e-71
NZ_CP007537.1\|WP_002989648.1\|874273_876592_+\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP007537.1\|WP_010922375.1\|861443_862457_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_CP007537.1\|WP_011285556.1\|869925_870699_+\|CAMP-factor-pore-forming-toxin-Cfa	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	9.547e-99
NZ_CP007537.1\|WP_010922370.1\|871067_872303_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	3.02963e-95
NZ_CP007537.1\|WP_002984447.1\|862519_864022_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_CP007537.1\|WP_010922374.1\|864972_866787_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP007537.1\|WP_009880239.1\|853708_854464_-\|streptococcal-pyrogenic-exotoxin-SpeA	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.19518e-22
NZ_CP007537.1\|WP_002984457.1\|868074_868704_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.89978e-111
NZ_CP007537.1\|WP_010922372.1\|868719_869556_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.19305e-109
NZ_CP007537.1\|WP_011285555.1\|872422_873745_-\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NZ_CP007537.1\|WP_010922377.1\|857697_858069_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	2.6897e-48
NZ_CP007537.1\|WP_010922376.1\|858253_861364_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
NZ_CP007537.1\|WP_002984469.1\|876955_877204_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
NZ_CP007537.1\|WP_002984437.1\|856999_857698_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.28377e-64
NZ_CP007537.1\|WP_011285558.1\|855463_856078_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.46451e-31

>NZ_CP007537.1|WP_002984449.1|864239_864797_+|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>NZ_CP007537.1|WP_002984447.1|862519_864022_+|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>NZ_CP007537.1|WP_010922375.1|861443_862457_+|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKDGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>NZ_CP007537.1|WP_010922376.1|858253_861364_+|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEIEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYFCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTAFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDALTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDITAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSVTEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>NZ_CP007537.1|WP_010922377.1|857697_858069_-|GntR-family-transcriptional-regulator
MSWKFEEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>NZ_CP007537.1|WP_002984437.1|856999_857698_-|ABC-transporter-ATP-binding-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>NZ_CP007537.1|WP_010922378.1|856204_856990_-|hypothetical-protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGWEGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>NZ_CP007537.1|WP_011285558.1|855463_856078_+|TVP38/TMEM64-family-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIALFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>NZ_CP007537.1|WP_011285559.1|854684_854873_+|hypothetical-protein
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK
>NZ_CP007537.1|WP_009880239.1|853708_854464_-|streptococcal-pyrogenic-exotoxin-SpeA
MENNKKVLKKMVFFVLVTFLGLTISQEVFAQQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNVSGPNYDKLKTELKNQEMATLFKDKNVDIYGVEYYHLCYLCENAERSACIYGGVTNHEGNHLEIPKKIVVKVSIDGIQSLSFDIETNKKMVTAQELDYKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMIYKDNETLDSNTSQIEVYLTTK
>NZ_CP007537.1|WP_010922374.1|864972_866787_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKSLSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>NZ_CP007537.1|WP_002989626.1|866982_867318_+|alkylphosphonate-utilization-protein
MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVVLDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMKLKSEFVKKI
>NZ_CP007537.1|WP_002992417.1|867423_868065_+|amino-acid-ABC-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>NZ_CP007537.1|WP_002984457.1|868074_868704_+|amino-acid-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQKADAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>NZ_CP007537.1|WP_010922372.1|868719_869556_+|amino-acid-ABC-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGRCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKERQDKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDSLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANIKS
>NZ_CP007537.1|WP_011285556.1|869925_870699_+|CAMP-factor-pore-forming-toxin-Cfa
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQANFQRDALVQKLDEGHQQLEAIKHEAKGTDIETTVNKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQDALETALKS
>NZ_CP007537.1|WP_010922370.1|871067_872303_-|cation-diffusion-facilitator-family-transporter
MTQDPIANLKLARKGPIVSIIVYLSLSVAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQFSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQITPIAKKQLHHTHYRIVKM
>NZ_CP007537.1|WP_011285555.1|872422_873745_-|sodium:alanine-symporter-family-protein
MIALVKLIDNLVWGPPLLILLVGTGIYLTSHLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILMVGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK
>NZ_CP007537.1|WP_002989648.1|874273_876592_+|DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>NZ_CP007537.1|WP_002984469.1|876955_877204_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP007537_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007537_4

1055712-1055827

Orphan

Consensus_repeat	Method
CCGTCTTTACCTGGAAGACCATCTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007537_4

>merge|NZ_CP007537|4|1055712-1055827|CRISPRCasFinder
GCTGGTTTACCTGGTTGACCGTCTTTACCTGGAAGACCATCTTTGCCATCTTGGCCATCCTTACCATCTTTACCGTTTTGGCCGTCCTTGCCGTCTTTACCTGGAAGACCATCTTT

>NZ_CP007537|4|4|1055712-1055827|CRISPRCasFinder
GCTGGTTTACCTGGTTGACCGTCTTT	ACCTGGAAGACCATCTTTGCCATCTTGGCCATCCTTACCATCTTTACCGTTTTGGCCGTCCTTG
CCGTCTTTACCTGGAAGACCATCTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007537.1\|WP_011017397.1\|1062939_1063212_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_010922256.1\|1053653_1054673_-\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_CP007537.1\|WP_002989931.1\|1050861_1051689_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_CP007537.1\|WP_011054447.1\|1060618_1060858_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_010922255.1\|1054787_1055225_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP007537.1\|WP_010922253.1\|1056486_1058319_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP007537.1\|WP_011285511.1\|1049076_1050726_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_CP007537.1\|WP_002989935.1\|1053021_1053447_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_CP007537.1\|WP_010922260.1\|1048284_1049073_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_CP007537.1\|WP_011054450.1\|1059453_1059663_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP007537.1\|WP_002984845.1\|1052511_1053003_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_CP007537.1\|WP_010922263.1\|1045899_1046466_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP007537.1\|WP_029714020.1\|1062715_1062943_-\|phage-holin	unknown	unknown	gnl\|CDD\|227833
NZ_CP007537.1\|WP_002984844.1\|1051685_1052495_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_CP007537.1\|WP_011054446.1\|1060915_1061272_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_029714017.1\|1059072_1059255_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_046735270.1\|1063223_1063862_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_029714018.1\|1061387_1062593_-\|glucosaminidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|224619
NZ_CP007537.1\|WP_015055942.1\|1047244_1048291_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270264
NZ_CP007537.1\|WP_011054448.1\|1060103_1060355_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP007537.1\|WP_010922256.1\|1053653_1054673_-\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	4.73129e-105
NZ_CP007537.1\|WP_002989931.1\|1050861_1051689_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_CP007537.1\|WP_010922255.1\|1054787_1055225_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.70819e-84
NZ_CP007537.1\|WP_010922253.1\|1056486_1058319_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP007537.1\|WP_011285511.1\|1049076_1050726_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	2.61115e-78
NZ_CP007537.1\|WP_002989935.1\|1053021_1053447_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	3.64459e-31
NZ_CP007537.1\|WP_010922260.1\|1048284_1049073_-\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.85343e-81
NZ_CP007537.1\|WP_011054450.1\|1059453_1059663_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.20712e-13
NZ_CP007537.1\|WP_002984845.1\|1052511_1053003_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
NZ_CP007537.1\|WP_010922263.1\|1045899_1046466_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	6.82316e-94
NZ_CP007537.1\|WP_029714020.1\|1062715_1062943_-\|phage-holin	gnl\|CDD\|227833	COG5546, COG5546, Small integral membrane protein [Function unknown].	3.77481e-34
NZ_CP007537.1\|WP_002984844.1\|1051685_1052495_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
NZ_CP007537.1\|WP_029714018.1\|1061387_1062593_-\|glucosaminidase-domain-containing-protein	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	1.04383e-58
NZ_CP007537.1\|WP_015055942.1\|1047244_1048291_-\|extracellular-solute-binding-protein	gnl\|CDD\|270264	cd13546, PBP2_BitB, Substrate binding domain of a putative iron transporter BitB, a member of the type 2 periplasmic binding fold superfamily. The substrate domain of this group shows a high homology to the periplasmic component of ferric iron transporter (Fbp), but its biochemical characterization has not been performed. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.97102e-92

>NZ_CP007537.1|WP_010922255.1|1054787_1055225_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>NZ_CP007537.1|WP_010922256.1|1053653_1054673_-|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLLALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGLQKWLRLDVNTATLVGVGSSICGGSAVAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHYLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_CP007537.1|WP_002989935.1|1053021_1053447_-|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_CP007537.1|WP_002984845.1|1052511_1053003_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_CP007537.1|WP_002984844.1|1051685_1052495_-|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>NZ_CP007537.1|WP_002989931.1|1050861_1051689_-|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_CP007537.1|WP_011285511.1|1049076_1050726_-|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRATHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLEVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_CP007537.1|WP_010922260.1|1048284_1049073_-|response-regulator-transcription-factor
MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFDMFEVTKDQTYAKIILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAHFQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC
>NZ_CP007537.1|WP_015055942.1|1047244_1048291_-|extracellular-solute-binding-protein
MLKLKRKWLLSFLLVIIILAIVNVAMYIFSSSKKDSAKELVILTPNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFESHKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQPALKGKIAFADPNSSSSAFSQLTNILLAKGGYTNADAWAYMKRLLVNMNSIRATSSSEVYQSVAEGKMIVGLTYEDPCINLQKSGANVSIVYPKEGTVFVPSSVAIIKHAPNMTEAKLFINFMLSRDVQNAFGQSTSNRPIRQDAQTSHDMKALETIATLKEDYAYVTKHKKKIVATYNQLRQRLEKAK
>NZ_CP007537.1|WP_010922263.1|1045899_1046466_-|sugar-O-acetyltransferase
MTTEFDKMTRGEWYDANFDSELIQKRMMAQDLCFDLNQLKPSREEERSAVLNQLFGQSFEGLVLLSPFICDYGKNITFGKNCFINSNCYFMDGAKIALGDNVFVGPSTGFYTANHPLDYKRRNEGLEKALPITIGDNVWFGANVNVMPGVTIGSGCVIASGSVVTHDIPVNSLAAGVPCQVVRKIEQE
>NZ_CP007537.1|WP_010922253.1|1056486_1058319_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK
>NZ_CP007537.1|WP_029714017.1|1059072_1059255_-|hypothetical-protein
MLTYDEFKQAIDNGYITADTVAIVRKNGLIFDYVLPHESVRSCEIVIEERVAEVMVELDK
>NZ_CP007537.1|WP_011054450.1|1059453_1059663_-|helix-turn-helix-transcriptional-regulator
MELYEFVGEQIRHQRKLAKLNQSQLAELLDTNQQTIGMMENGKRRATLQDLVKLRKIFNVSVDDFLPKD
>NZ_CP007537.1|WP_011054448.1|1060103_1060355_+|hypothetical-protein
MEYGNKIFEIYNKPFKYRNSSSTNYNKVRASGIEPNTKFVVNKTANINCAVYPRHGSIEKVFYWGDRKITQATAEKRCGYFKG
>NZ_CP007537.1|WP_011054447.1|1060618_1060858_+|hypothetical-protein
MKYFVTDIENIDNITVFEEFGFDFTESEEGIWYTEEKAMFDWWNELAQAIEFLNDNEINAETNELADYITIAKENGFEF
>NZ_CP007537.1|WP_011054446.1|1060915_1061272_+|hypothetical-protein
MTKTTAQRKKSIYINGALEKIYDECSNALRNRTFSGRVMDIAERYDALMGLTEIPELTPQQQMILGEAVLGAFMDRNKIRYLHDAIADTEIDGCLDLAKMVRDLDYAQRLKLIESINI
>NZ_CP007537.1|WP_029714018.1|1061387_1062593_-|glucosaminidase-domain-containing-protein
MAFLDKIKSAVIAEWHTHKILPSLTAAQAILESGCGKHAPHNALFGIKADRSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWEDSIADHGQFLVDNPRYKAVIGEADYKKACHAIKDAGYATASGYADLLIQLIEENNLQEWDAEAIKNKEEQMISSQCREVIEFFINLANAGVGVDKDSFAGWQCADVPCYAAKHWFGVDLWGNAIDLLDSAAAVGWEVHRMPTDANPRTGAFFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNNRDFTGVIGWFYPPYQGDAVTQTVSTEPQTSDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGIYKQGDTVSFDSEGYANGYYWISYVGDSGKRSYMAIGITDKDGNIISLWGKLV
>NZ_CP007537.1|WP_029714020.1|1062715_1062943_-|phage-holin
MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAVTLLVLLGVVADPTTKGLSDSEQALTYHEPKK
>NZ_CP007537.1|WP_011017397.1|1062939_1063212_-|hypothetical-protein
MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHLKIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA
>NZ_CP007537.1|WP_046735270.1|1063223_1063862_-|hypothetical-protein
MKTLTLSGKPYPIHEGGKVVKTEVRLIGDNGLFIPIELIGDQTAKGADDLIKEGLDAFVREYVTKYAVAESVQKVEELSLAQKEIEQNAEQAKVTAEAAEKQAKSLELVIAKSQKMANLQAIHLLTSGSKVEPDIYKGLLELIEPAKQGEYQAYDVFTVVDSTKEEDGEAGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP007537_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007537_5

1751135-1751252

Orphan

Consensus_repeat	Method
CTCCATATGGTGGAGTGTAAGGGTCAATTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007537_5

>merge|NZ_CP007537|5|1751135-1751252|CRISPRCasFinder
CTCCATATGGTGGAGTGTAAGGGTCAATTGCTACCGTACCAGGTCCTCCCCAATCATCACGTTTTTCATACCCTGTACCTAATGCTCCTCCATATGGTGGAGTGTAAGGGTCAGTTGC

>NZ_CP007537|5|5|1751135-1751252|CRISPRCasFinder
CTCCATATGGTGGAGTGTAAGGGTCAATTGC	TACCGTACCAGGTCCTCCCCAATCATCACGTTTTTCATACCCTGTACCTAATGCTC
CTCCATATGGTGGAGTGTAAGGGTCAGTTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007537.1\|WP_002987954.1\|1742473_1743394_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	unknown	unknown	gnl\|CDD\|238499
NZ_CP007537.1\|WP_011285743.1\|1753169_1754624_-\|M-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP007537.1\|WP_046735277.1\|1751827_1752958_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP007537.1\|WP_010922707.1\|1734572_1736201_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173883
NZ_CP007537.1\|WP_010922716.1\|1757401_1759027_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP007537.1\|WP_029714151.1\|1737287_1738109_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_CP007537.1\|WP_003059481.1\|1738120_1738924_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_CP007537.1\|WP_002991237.1\|1760513_1761167_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP007537.1\|WP_029714102.1\|1759128_1760517_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP007537.1\|WP_010922709.1\|1739983_1742461_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|273578
NZ_CP007537.1\|WP_002982458.1\|1762490_1763165_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP007537.1\|WP_029714149.1\|1743629_1744913_-\|LPXTG-anchored-fibronectin-binding-protein-FbpA	unknown	unknown	gnl\|CDD\|236090
NZ_CP007537.1\|WP_009880585.1\|1736313_1737291_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_CP007537.1\|WP_046735278.1\|1754767_1756396_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470
NZ_CP007537.1\|WP_002982472.1\|1757071_1757323_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_010922708.1\|1738907_1739534_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
NZ_CP007537.1\|WP_002993552.1\|1761260_1762478_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NZ_CP007537.1\|WP_010922718.1\|1763151_1764420_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|223914
NZ_CP007537.1\|WP_011285740.1\|1745009_1748504_-\|C5a-peptidase-ScpA/B	unknown	unknown	gnl\|CDD\|173801
NZ_CP007537.1\|WP_002982507.1\|1739614_1739815_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777

Protein	Function_ID	Function_description	E-value
NZ_CP007537.1\|WP_002987954.1\|1742473_1743394_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	1.92404e-123
NZ_CP007537.1\|WP_011285743.1\|1753169_1754624_-\|M-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	4.3159e-14
NZ_CP007537.1\|WP_046735277.1\|1751827_1752958_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.86228e-11
NZ_CP007537.1\|WP_010922707.1\|1734572_1736201_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173883	cd08518, PBP2_NikA_DppA_OppA_like_19, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP007537.1\|WP_010922716.1\|1757401_1759027_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	3.47983e-59
NZ_CP007537.1\|WP_029714151.1\|1737287_1738109_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.20638e-69
NZ_CP007537.1\|WP_003059481.1\|1738120_1738924_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.85753e-80
NZ_CP007537.1\|WP_002991237.1\|1760513_1761167_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.27645e-69
NZ_CP007537.1\|WP_029714102.1\|1759128_1760517_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.93331e-31
NZ_CP007537.1\|WP_010922709.1\|1739983_1742461_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|273578	TIGR01363, pneumococcal_histidine_triad_A_protein, streptococcal histidine triad protein. This model represents the N-terminal half of a family of Streptococcal proteins that contain a signal peptide and then up to five repeats of a region that includes a His-X-X-His-X-His (histidine triad) motif. Three repeats are found in the seed alignment. Additional copies in more poorly conserved regions may be detected. Members of this family from Streptococcus pneumoniae are suggested to cleave human C3, and the member PhpA has been shown in vaccine studies to be a protective antigen in mice. [Cellular processes, Pathogenesis].	0
NZ_CP007537.1\|WP_002982458.1\|1762490_1763165_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	8.84255e-116
NZ_CP007537.1\|WP_029714149.1\|1743629_1744913_-\|LPXTG-anchored-fibronectin-binding-protein-FbpA	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	8.34716e-15
NZ_CP007537.1\|WP_009880585.1\|1736313_1737291_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.29179e-108
NZ_CP007537.1\|WP_046735278.1\|1754767_1756396_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	3.21741e-75
NZ_CP007537.1\|WP_010922708.1\|1738907_1739534_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.43974e-90
NZ_CP007537.1\|WP_002993552.1\|1761260_1762478_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.49497e-52
NZ_CP007537.1\|WP_010922718.1\|1763151_1764420_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|223914	COG0845, AcrA, Membrane-fusion protein [Cell envelope biogenesis, outer membrane].	1.56712e-22
NZ_CP007537.1\|WP_011285740.1\|1745009_1748504_-\|C5a-peptidase-ScpA/B	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.18321e-75
NZ_CP007537.1\|WP_002982507.1\|1739614_1739815_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	7.43573e-06

>NZ_CP007537.1|WP_011285740.1|1745009_1748504_-|C5a-peptidase-ScpA/B
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQAVETPQPTAVSEEAPSSKETKTPQTPDDAEETIADDANDLAPQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIIDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENPQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKLFALAPKALYETSWQKITIPANSSKQVTIPIDVSQFSKDLLAPMKNGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQAPDKKPETKPEQDGSGQAPDKKPETKPEQDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTKDQLPTTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED
>NZ_CP007537.1|WP_029714149.1|1743629_1744913_-|LPXTG-anchored-fibronectin-binding-protein-FbpA
MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDGIPPISLTQKTTATTSENWHHIDKDGLIPLGISLEAAKEEFKKEVEESRLSEAQKETYKQKIKTAPDKDKLLFTYHSEYMTAVKDLPASTESTTQPVEAPVQETQASASDSMVTGDSTSVTTDSPEETPSSESPVAPALSEAPAQPAESEEPSVAASSEETPSPSTPAAPETPEEPAAPSPSPESEEPSVAAPSEETPSPETPAAPETPEEPATPSPSPESEEPSVAASSEETPSPSTPAAPSTPAAPETPEEPAAPSQPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHESGKYLPSTGEKAQPLFIATMTLMSLFGSLLVTKRQKETKK
>NZ_CP007537.1|WP_002987954.1|1742473_1743394_-|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb
MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
>NZ_CP007537.1|WP_010922709.1|1739983_1742461_-|pneumococcal-type-histidine-triad-protein
MKKTYGYIGSVAAILLATHIGSYQLGKHHMGSATKDNQIAYIDDSKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAIISEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVAKGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVPHGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPAPGRRKAPIPDVTPNPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDDDSGSDHSKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDIWSKPGHEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQPEGVQFYNKNGELVTYDIKTLQQINP
>NZ_CP007537.1|WP_002982507.1|1739614_1739815_-|CsbD-family-protein
MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
>NZ_CP007537.1|WP_010922708.1|1738907_1739534_+|ABC-transporter-ATP-binding-protein
MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTSLSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYPSQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQASVWKSLLEIVKDRNLGLIIISHEFDMLEKLCDACYMIEENRTQLFKHT
>NZ_CP007537.1|WP_003059481.1|1738120_1738924_+|ABC-transporter-ATP-binding-protein
MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLAIIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVNYLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTCISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITIFKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG
>NZ_CP007537.1|WP_029714151.1|1737287_1738109_+|ABC-transporter-permease
MILKRRTVVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKNKAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>NZ_CP007537.1|WP_009880585.1|1736313_1737291_+|ABC-transporter-permease
MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNYDTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGDLGTSLVYRQPVSDIIRSRAGASFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRVKHLMLPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV
>NZ_CP007537.1|WP_010922707.1|1734572_1736201_+|ABC-transporter-substrate-binding-protein
MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELVVSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSFDLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHSTFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFKKWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKKGVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWNPKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVAEQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNITFYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIGDKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK
>NZ_CP007537.1|WP_046735277.1|1751827_1752958_-|YSIRK-type-signal-peptide-containing-protein
MTRQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTTVKAEGAKIDWQEEYKKLDEDNAKLVEVVETTSLENEKLKSENEENKKNLDKLSKENQGKLEKLELDYLKKLDHEHKEHQKEQQEQEERQKNQEQLERKYQREVEKRYQEQLQKQQQLETEKQISEASRKSLSRDLEASRAAKKDLEAEHQKLEAEHQKLKEDKQISDASRQGLSRDLEASRAAKKELEANHQKLEAEHQKLKEDKQISDASRQGLSRDLEASRAAKKELEANHQKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDTKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN
>NZ_CP007537.1|WP_011285743.1|1753169_1754624_-|M-protein
MAKNNTNRHYSLRKLKTGTASVAVALTVLGAGFANQTEVKANGDGNPREVIEDLAANNPAIQNIRLRHENKDLKARLENAMEVAGRDFKRAEELEKAKQALEDQRKDLETKLKELQQDYDLAKESTSWDRQRLEKELEEKKEALELAIDQASRDYHRATALEKELEEKKKALELAIDQASQDYNRANVLEKELETITREQEINRNLLGNAKLELDQLSSEKEQLTIEKAKLEEEKQISDASRQSLRRDLDASREAKKQVEKDLANLTAELDKVKEDKQISDASRQGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDTKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN
>NZ_CP007537.1|WP_046735278.1|1754767_1756396_-|helix-turn-helix-domain-containing-protein
MYVSKLFTSQQWRELKLISYVTENADAIGVKDKELSKALNISMLTLQTCLTNMQFMKEVGGITYKNGYITIWYHQHCGLQEVYQKALRHSQSFKLLETLFFRDFNSLEELAEELFVSLSTLKRLIKKTNAYLMHTFGITILTSPVQVSGDEHQIRLFYLKYFSEAYKISEWPFGEILNLKNCERLLSLMIKEVDVRVNFTLFQHLKILSSVNLIRYYKGHSAVYDNKKTSQRFSQLIQSSLEFQDLSRLFHLKFGLYLDETTIAEMFSNHVNDQLEIGYAFDSIKQDSPTGCRKVTNWVHLLDELEIRLNLSVTNKYEVAVILHNTTVLKEEDITANYLFFDYKKSYLNFYKQEHPHLYKAFVAGVEKLMRSEKEPISTELTNQLIYAFFITWENSFLKVNQKDEKIRLLVIERSFNSVGNFLKKYVGEFFSITNFNELDALTIDLEEIEKQYDVIVTDVMVGKSEELEIFFFDKMIPEAIIDKLNAFLNISFADSLPLDKPINPLDFHRKEVILPTPPNKLHAPLHNLDSLTVATQKQIHH
>NZ_CP007537.1|WP_002982472.1|1757071_1757323_-|hypothetical-protein
MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQPSMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD
>NZ_CP007537.1|WP_010922716.1|1757401_1759027_-|CHAP-domain-containing-protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTADTDTDDESETPKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKPNKDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKTPEKGPEKATDKTPEPNRDAPKPIQPPLAAAPVFIPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP
>NZ_CP007537.1|WP_029714102.1|1759128_1760517_-|HAMP-domain-containing-histidine-kinase
MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKCEFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDSQNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLIFSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRLYASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSIIGMIDGMLYNVGDFADRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSELKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEAETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWMVFTIDFPSHHDD
>NZ_CP007537.1|WP_002991237.1|1760513_1761167_-|response-regulator-transcription-factor
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE
>NZ_CP007537.1|WP_002993552.1|1761260_1762478_-|ABC-transporter-permease
MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIEALRFE
>NZ_CP007537.1|WP_002982458.1|1762490_1763165_-|ABC-transporter-ATP-binding-protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNIEHSDIE
>NZ_CP007537.1|WP_010922718.1|1763151_1764420_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKEVFVKKGDVVKVGQPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQDKIAQPLPGMKDGMEVGSIVKP

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Crispr_ID: NZ_CP007537_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007537_6

1754092-1754225

Orphan

Consensus_repeat	Method
TGGTCTATCGCTAATTCAAGAGCTTTCTTTTTCTCTTCTAACTCTTTTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007537_6

>merge|NZ_CP007537|6|1754092-1754225|CRISPRCasFinder
TGGTCTATCGCTAATTCAAGAGCTTTCTTTTTCTCTTCTAACTCTTTTTCTAAAGCGGTAGCTCTATGGTAGTCCCGACTTGCCTGGTCTATCGCTAATTCAAGAGCTTCCTTTTTCTCTTCTAACTCTTTTTC

>NZ_CP007537|6|6|1754092-1754225|CRISPRCasFinder
TGGTCTATCGCTAATTCAAGAGCTTTCTTTTTCTCTTCTAACTCTTTTTC	TAAAGCGGTAGCTCTATGGTAGTCCCGACTTGCC
TGGTCTATCGCTAATTCAAGAGCTTCCTTTTTCTCTTCTAACTCTTTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007537.1\|WP_002987954.1\|1742473_1743394_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	unknown	unknown	gnl\|CDD\|238499
NZ_CP007537.1\|WP_010922718.1\|1763151_1764420_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|223914
NZ_CP007537.1\|WP_002982442.1\|1764842_1765127_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_046735277.1\|1751827_1752958_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP007537.1\|WP_029714151.1\|1737287_1738109_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_CP007537.1\|WP_010922716.1\|1757401_1759027_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP007537.1\|WP_003059481.1\|1738120_1738924_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_CP007537.1\|WP_002991237.1\|1760513_1761167_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP007537.1\|WP_029714102.1\|1759128_1760517_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP007537.1\|WP_010922709.1\|1739983_1742461_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|273578
NZ_CP007537.1\|WP_002982458.1\|1762490_1763165_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP007537.1\|WP_029714149.1\|1743629_1744913_-\|LPXTG-anchored-fibronectin-binding-protein-FbpA	unknown	unknown	gnl\|CDD\|236090
NZ_CP007537.1\|WP_046735276.1\|1750721_1751639_-\|lysis-inhibitor-protein	unknown	unknown	gnl\|CDD\|281480
NZ_CP007537.1\|WP_046735278.1\|1754767_1756396_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470
NZ_CP007537.1\|WP_002982472.1\|1757071_1757323_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007537.1\|WP_010922708.1\|1738907_1739534_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
NZ_CP007537.1\|WP_002993552.1\|1761260_1762478_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NZ_CP007537.1\|WP_002982439.1\|1765273_1765570_-\|DUF4298-domain-containing-protein	unknown	unknown	gnl\|CDD\|372919
NZ_CP007537.1\|WP_011285740.1\|1745009_1748504_-\|C5a-peptidase-ScpA/B	unknown	unknown	gnl\|CDD\|173801
NZ_CP007537.1\|WP_002982507.1\|1739614_1739815_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777

Protein	Function_ID	Function_description	E-value
NZ_CP007537.1\|WP_002987954.1\|1742473_1743394_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	1.92404e-123
NZ_CP007537.1\|WP_010922718.1\|1763151_1764420_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|223914	COG0845, AcrA, Membrane-fusion protein [Cell envelope biogenesis, outer membrane].	1.56712e-22
NZ_CP007537.1\|WP_046735277.1\|1751827_1752958_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.86228e-11
NZ_CP007537.1\|WP_029714151.1\|1737287_1738109_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.20638e-69
NZ_CP007537.1\|WP_010922716.1\|1757401_1759027_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	3.47983e-59
NZ_CP007537.1\|WP_003059481.1\|1738120_1738924_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.85753e-80
NZ_CP007537.1\|WP_002991237.1\|1760513_1761167_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.27645e-69
NZ_CP007537.1\|WP_029714102.1\|1759128_1760517_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.93331e-31
NZ_CP007537.1\|WP_010922709.1\|1739983_1742461_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|273578	TIGR01363, pneumococcal_histidine_triad_A_protein, streptococcal histidine triad protein. This model represents the N-terminal half of a family of Streptococcal proteins that contain a signal peptide and then up to five repeats of a region that includes a His-X-X-His-X-His (histidine triad) motif. Three repeats are found in the seed alignment. Additional copies in more poorly conserved regions may be detected. Members of this family from Streptococcus pneumoniae are suggested to cleave human C3, and the member PhpA has been shown in vaccine studies to be a protective antigen in mice. [Cellular processes, Pathogenesis].	0
NZ_CP007537.1\|WP_002982458.1\|1762490_1763165_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	8.84255e-116
NZ_CP007537.1\|WP_029714149.1\|1743629_1744913_-\|LPXTG-anchored-fibronectin-binding-protein-FbpA	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	8.34716e-15
NZ_CP007537.1\|WP_046735276.1\|1750721_1751639_-\|lysis-inhibitor-protein	gnl\|CDD\|281480	pfam03482, SIC, sic protein repeat. Serotype M1 group A Streptococcus strains cause epidemic waves of human infections. This 30 aa repeat occurs in the sic protein, an extracellular protein (streptococcal inhibitor of complement) that inhibits human complement.	3.95995e-07
NZ_CP007537.1\|WP_046735278.1\|1754767_1756396_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	3.21741e-75
NZ_CP007537.1\|WP_010922708.1\|1738907_1739534_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.43974e-90
NZ_CP007537.1\|WP_002993552.1\|1761260_1762478_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.49497e-52
NZ_CP007537.1\|WP_002982439.1\|1765273_1765570_-\|DUF4298-domain-containing-protein	gnl\|CDD\|372919	pfam14131, DUF4298, Domain of unknown function (DUF4298). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 94 and 105 amino acids in length. There are two completely conserved residues (Y and D) that may be functionally important.	2.929e-24
NZ_CP007537.1\|WP_011285740.1\|1745009_1748504_-\|C5a-peptidase-ScpA/B	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.18321e-75
NZ_CP007537.1\|WP_002982507.1\|1739614_1739815_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	7.43573e-06

>NZ_CP007537.1|WP_046735277.1|1751827_1752958_-|YSIRK-type-signal-peptide-containing-protein
MTRQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTTVKAEGAKIDWQEEYKKLDEDNAKLVEVVETTSLENEKLKSENEENKKNLDKLSKENQGKLEKLELDYLKKLDHEHKEHQKEQQEQEERQKNQEQLERKYQREVEKRYQEQLQKQQQLETEKQISEASRKSLSRDLEASRAAKKDLEAEHQKLEAEHQKLKEDKQISDASRQGLSRDLEASRAAKKELEANHQKLEAEHQKLKEDKQISDASRQGLSRDLEASRAAKKELEANHQKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDTKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN
>NZ_CP007537.1|WP_046735276.1|1750721_1751639_-|lysis-inhibitor-protein
MNIRNKIENSKTLLFTSLVAVALLGATQPVSAETYTSRNFDWSGDDWPEDDWSGDGLSKYDRSGVGLSQYGWSQYGWSSDKEEWPEDWPEDDWSSDKKDETEDKTRPPYGEALGTGYEKRDDWGGPGTVATDPYTPPYGGALGTGYEKRDDWGGPGTVAIDPYTPPYGEALGTGYEKRDDWRGPGHIPKPENEQSPNPSHIPEPPQIEWPQWNGFDELSFGPSDWGQSEDAPRFPSEPRVPEKPQHTPQKNPQESDFDRGFSAGLKAKNSGRGIDFEGFQYGGWSDEYKKGYMQAFGTPYTPSAT
>NZ_CP007537.1|WP_011285740.1|1745009_1748504_-|C5a-peptidase-ScpA/B
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQAVETPQPTAVSEEAPSSKETKTPQTPDDAEETIADDANDLAPQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIIDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENPQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKLFALAPKALYETSWQKITIPANSSKQVTIPIDVSQFSKDLLAPMKNGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQAPDKKPETKPEQDGSGQAPDKKPETKPEQDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTKDQLPTTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED
>NZ_CP007537.1|WP_029714149.1|1743629_1744913_-|LPXTG-anchored-fibronectin-binding-protein-FbpA
MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDGIPPISLTQKTTATTSENWHHIDKDGLIPLGISLEAAKEEFKKEVEESRLSEAQKETYKQKIKTAPDKDKLLFTYHSEYMTAVKDLPASTESTTQPVEAPVQETQASASDSMVTGDSTSVTTDSPEETPSSESPVAPALSEAPAQPAESEEPSVAASSEETPSPSTPAAPETPEEPAAPSPSPESEEPSVAAPSEETPSPETPAAPETPEEPATPSPSPESEEPSVAASSEETPSPSTPAAPSTPAAPETPEEPAAPSQPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHESGKYLPSTGEKAQPLFIATMTLMSLFGSLLVTKRQKETKK
>NZ_CP007537.1|WP_002987954.1|1742473_1743394_-|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb
MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
>NZ_CP007537.1|WP_010922709.1|1739983_1742461_-|pneumococcal-type-histidine-triad-protein
MKKTYGYIGSVAAILLATHIGSYQLGKHHMGSATKDNQIAYIDDSKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAIISEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVAKGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVPHGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPAPGRRKAPIPDVTPNPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDDDSGSDHSKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDIWSKPGHEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQPEGVQFYNKNGELVTYDIKTLQQINP
>NZ_CP007537.1|WP_002982507.1|1739614_1739815_-|CsbD-family-protein
MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
>NZ_CP007537.1|WP_010922708.1|1738907_1739534_+|ABC-transporter-ATP-binding-protein
MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTSLSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYPSQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQASVWKSLLEIVKDRNLGLIIISHEFDMLEKLCDACYMIEENRTQLFKHT
>NZ_CP007537.1|WP_003059481.1|1738120_1738924_+|ABC-transporter-ATP-binding-protein
MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLAIIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVNYLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTCISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITIFKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG
>NZ_CP007537.1|WP_029714151.1|1737287_1738109_+|ABC-transporter-permease
MILKRRTVVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKNKAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>NZ_CP007537.1|WP_046735278.1|1754767_1756396_-|helix-turn-helix-domain-containing-protein
MYVSKLFTSQQWRELKLISYVTENADAIGVKDKELSKALNISMLTLQTCLTNMQFMKEVGGITYKNGYITIWYHQHCGLQEVYQKALRHSQSFKLLETLFFRDFNSLEELAEELFVSLSTLKRLIKKTNAYLMHTFGITILTSPVQVSGDEHQIRLFYLKYFSEAYKISEWPFGEILNLKNCERLLSLMIKEVDVRVNFTLFQHLKILSSVNLIRYYKGHSAVYDNKKTSQRFSQLIQSSLEFQDLSRLFHLKFGLYLDETTIAEMFSNHVNDQLEIGYAFDSIKQDSPTGCRKVTNWVHLLDELEIRLNLSVTNKYEVAVILHNTTVLKEEDITANYLFFDYKKSYLNFYKQEHPHLYKAFVAGVEKLMRSEKEPISTELTNQLIYAFFITWENSFLKVNQKDEKIRLLVIERSFNSVGNFLKKYVGEFFSITNFNELDALTIDLEEIEKQYDVIVTDVMVGKSEELEIFFFDKMIPEAIIDKLNAFLNISFADSLPLDKPINPLDFHRKEVILPTPPNKLHAPLHNLDSLTVATQKQIHH
>NZ_CP007537.1|WP_002982472.1|1757071_1757323_-|hypothetical-protein
MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQPSMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD
>NZ_CP007537.1|WP_010922716.1|1757401_1759027_-|CHAP-domain-containing-protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTADTDTDDESETPKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKPNKDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKTPEKGPEKATDKTPEPNRDAPKPIQPPLAAAPVFIPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP
>NZ_CP007537.1|WP_029714102.1|1759128_1760517_-|HAMP-domain-containing-histidine-kinase
MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKCEFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDSQNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLIFSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRLYASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSIIGMIDGMLYNVGDFADRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSELKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEAETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWMVFTIDFPSHHDD
>NZ_CP007537.1|WP_002991237.1|1760513_1761167_-|response-regulator-transcription-factor
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE
>NZ_CP007537.1|WP_002993552.1|1761260_1762478_-|ABC-transporter-permease
MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIEALRFE
>NZ_CP007537.1|WP_002982458.1|1762490_1763165_-|ABC-transporter-ATP-binding-protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNIEHSDIE
>NZ_CP007537.1|WP_010922718.1|1763151_1764420_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKEVFVKKGDVVKVGQPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQDKIAQPLPGMKDGMEVGSIVKP
>NZ_CP007537.1|WP_002982442.1|1764842_1765127_-|hypothetical-protein
MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKDDAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN
>NZ_CP007537.1|WP_002982439.1|1765273_1765570_-|DUF4298-domain-containing-protein
MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLRNFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	NZ_CP007537.1	1364620-1364652	0	1.0
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	NZ_CP007537.1	1065475-1065507	1	0.97
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	NZ_CP007537.1	528163-528196	2	0.941

1. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to position: 1364620-1364652, mismatch: 0, identity: 1.0

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggtttgcttta	Protospacer
*********************************

2. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to position: 1065475-1065507, mismatch: 1, identity: 0.97

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

3. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to position: 528163-528196, mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448690	Streptococcus phage Javan169, complete genome	23669-23701	0	1.0
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448694	Streptococcus phage Javan179, complete genome	22038-22070	0	1.0
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	MK448961	Streptococcus phage Javan494, complete genome	33452-33484	0	1.0
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	MK448766	Streptococcus phage Javan465, complete genome	34324-34356	0	1.0
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448973	Streptococcus phage Javan522, complete genome	12058-12092	1	0.971
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	NC_028700	Streptococcus phage T12, complete genome	12019-12053	1	0.971
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448778	Streptococcus phage Javan493, complete genome	12073-12107	1	0.971
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448686	Streptococcus phage Javan157, complete genome	14021-14055	1	0.971
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448949	Streptococcus phage Javan460, complete genome	13943-13977	1	0.971
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448958	Streptococcus phage Javan486, complete genome	11818-11852	1	0.971
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448950	Streptococcus phage Javan464, complete genome	12065-12099	1	0.971
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448782	Streptococcus phage Javan501, complete genome	14704-14738	1	0.971
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448955	Streptococcus phage Javan478, complete genome	24096-24128	1	0.97
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	MK448779	Streptococcus phage Javan497, complete genome	33182-33214	1	0.97
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	MK448792	Streptococcus phage Javan521, complete genome	33433-33465	1	0.97
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	NC_004584	Streptococcus prophage 315.1, complete genome	33026-33058	1	0.97
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	MK448962	Streptococcus phage Javan496, complete genome	24582-24614	1	0.97
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	MK448770	Streptococcus phage Javan477, complete genome	33433-33465	1	0.97
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	MK448978	Streptococcus phage Javan532, complete genome	32920-32952	1	0.97
NZ_CP007537_1	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	MK448785	Streptococcus phage Javan507, complete genome	32921-32953	1	0.97
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448771	Streptococcus phage Javan481, complete genome	9182-9216	2	0.943
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK449012	Streptococcus phage Javan94, complete genome	11655-11689	2	0.943
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	NC_004585	Streptococcus prophage 315.2, complete genome	13820-13854	2	0.943
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448955	Streptococcus phage Javan478, complete genome	13318-13352	2	0.943
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448966	Streptococcus phage Javan508, complete genome	13675-13709	2	0.943
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448795	Streptococcus phage Javan527, complete genome	17680-17714	2	0.943
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448772	Streptococcus phage Javan483, complete genome	13690-13724	2	0.943
NZ_CP007537_1	1.1\|598494\|35\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598494-598528	35	MK448673	Streptococcus phage Javan119, complete genome	13071-13105	2	0.943
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448749	Streptococcus phage Javan39, complete genome	23029-23061	2	0.939
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448859	Streptococcus phage Javan170, complete genome	23306-23338	2	0.939
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448962	Streptococcus phage Javan496, complete genome	12253-12285	2	0.939
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448850	Streptococcus phage Javan132, complete genome	22898-22930	2	0.939
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448676	Streptococcus phage Javan131, complete genome	25821-25853	2	0.939
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448688	Streptococcus phage Javan161, complete genome	23264-23296	2	0.939
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	MK448960	Streptococcus phage Javan492, complete genome	13786-13819	2	0.941
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	MK448762	Streptococcus phage Javan447, complete genome	13913-13946	2	0.941
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	MK448791	Streptococcus phage Javan517, complete genome	12700-12733	2	0.941
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	NC_004587	Streptococcus prophage 315.4, complete genome	12795-12828	2	0.941
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	14065-14098	2	0.941
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	MK448977	Streptococcus phage Javan530, complete genome	12700-12733	2	0.941
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	MK448783	Streptococcus phage Javan503, complete genome	13616-13649	2	0.941
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	MK448788	Streptococcus phage Javan511, complete genome	12700-12733	2	0.941
NZ_CP007537_1	1.3\|598626\|34\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598626-598659	34	MK448954	Streptococcus phage Javan476, complete genome	13389-13422	2	0.941
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MK448675	Streptococcus phage Javan129, complete genome	23801-23833	3	0.909
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MT774411	CrAssphage cr273_1, complete genome	18559-18591	9	0.727
NZ_CP007537_1	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	MT774410	CrAssphage cr272_1, complete genome	18954-18986	9	0.727

1. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 0, identity: 1.0

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggtttgcttta	Protospacer
*********************************

2. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 0, identity: 1.0

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggtttgcttta	Protospacer
*********************************

3. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448961 (Streptococcus phage Javan494, complete genome) position: , mismatch: 0, identity: 1.0

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcataccttgatttgagcgagtaaactc	Protospacer
*********************************

4. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448766 (Streptococcus phage Javan465, complete genome) position: , mismatch: 0, identity: 1.0

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcataccttgatttgagcgagtaaactc	Protospacer
*********************************

5. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 1, identity: 0.971

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaattacatcag	Protospacer
****.******************************

6. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NC_028700 (Streptococcus phage T12, complete genome) position: , mismatch: 1, identity: 0.971

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaattacatcag	Protospacer
****.******************************

7. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 1, identity: 0.971

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaattacatcag	Protospacer
****.******************************

8. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 1, identity: 0.971

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaattacatcag	Protospacer
****.******************************

9. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 1, identity: 0.971

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaattacatcag	Protospacer
****.******************************

10. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 1, identity: 0.971

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaattacatcag	Protospacer
****.******************************

11. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 1, identity: 0.971

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaattacatcag	Protospacer
****.******************************

12. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 1, identity: 0.971

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaattacatcag	Protospacer
****.******************************

13. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 1, identity: 0.97

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcgttttctgcttctgctaggtttgcttta	Protospacer
*****.***************************

14. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 1, identity: 0.97

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

15. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448792 (Streptococcus phage Javan521, complete genome) position: , mismatch: 1, identity: 0.97

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

16. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 1, identity: 0.97

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

17. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 1, identity: 0.97

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

18. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448770 (Streptococcus phage Javan477, complete genome) position: , mismatch: 1, identity: 0.97

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

19. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 1, identity: 0.97

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

20. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 1, identity: 0.97

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

21. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 2, identity: 0.943

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatgtcacgaaaatcaccaattacatcag	Protospacer
****.****.*************************

22. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 2, identity: 0.943

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatatcacgaaaatcaccaatcacatcag	Protospacer
****.**********************.*******

23. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 2, identity: 0.943

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatgtcacgaaaatcaccaattacatcag	Protospacer
****.****.*************************

24. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 2, identity: 0.943

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatgtcacgaaaatcaccaattacatcag	Protospacer
****.****.*************************

25. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 2, identity: 0.943

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatgtcacgaaaatcaccaattacatcag	Protospacer
****.****.*************************

26. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 2, identity: 0.943

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatgtcacgaaaatcaccaattacatcag	Protospacer
****.****.*************************

27. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 2, identity: 0.943

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaaaggcatgtcacgaaaatcaccaattacatcag	Protospacer
****.****.*************************

28. spacer 1.1|598494|35|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 2, identity: 0.943

aaaaagcatatcacgaaaatcaccaattacatcag	CRISPR spacer
aaatggcatatcacgaaaatcaccaattacatcag	Protospacer
*** .******************************

29. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 2, identity: 0.939

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcgttttctgcttctgctaggcttgcttta	Protospacer
*****.******************.********

30. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 2, identity: 0.939

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggctcgcttta	Protospacer
************************.*.******

31. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 2, identity: 0.939

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcgttttctgcttctgctaggttcgcttta	Protospacer
*****.********************.******

32. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 2, identity: 0.939

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggctcgcttta	Protospacer
************************.*.******

33. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 2, identity: 0.939

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggctcgcttta	Protospacer
************************.*.******

34. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 2, identity: 0.939

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggctcgcttta	Protospacer
************************.*.******

35. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

36. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

37. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

38. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

39. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

40. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

41. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448783 (Streptococcus phage Javan503, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

42. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

43. spacer 1.3|598626|34|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 2, identity: 0.941

tttttactttgattacatcccgcaatgtcacagc	CRISPR spacer
tttttgctttgattacattccgcaatgtcacagc	Protospacer
*****.************.***************

44. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 3, identity: 0.909

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctactaagtttgctttg	Protospacer
******************.***.*********.

45. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MT774411 (CrAssphage cr273_1, complete genome) position: , mismatch: 9, identity: 0.727

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
gtatatgtatctgcttctgctgggtttgctgta	Protospacer
. .*   * ************.******** **

46. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to MT774410 (CrAssphage cr272_1, complete genome) position: , mismatch: 9, identity: 0.727

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
gtatatgtatctgcttctgctgggtttgctgta	Protospacer
. .*   * ************.******** **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

30839 : 43152

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015055883.1\|30839_34565_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.5e-38	27.3
WP_010921773.1\|34725_36180_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.8e-54	32.7
WP_010921774.1\|36207_37230_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	1.1e-63	42.1
WP_010921775.1\|37397_37952_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.2e-25	36.1
WP_011285343.1\|38135_39683_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	8.3e-44	51.3
WP_010921776.1\|39740_40865_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_010921777.1\|41117_42383_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002987716.1\|42660_43152_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.2e-18	42.3

DBSCAN-SWA_2

491473 : 557008

Temperate_phage(49.15%)

integrase,tRNA,holin,portal,terminase,tail,capsid

attL 499629:499646|attR 526810:526827

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029714068.1\|491473_492409_+\|tRNA	methionyl-tRNA formyltransferase	M4QRX9	Synechococcus_phage	6.0e-05	38.5
WP_002983657.1\|492398_493721_+	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_002983660.1\|493758_494499_+	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_010922538.1\|494495_496394_+	Stk1 family PASTA domain-containing Ser/Thr kinase	B5LWE2	Feldmannia_species_virus	1.4e-21	30.7
WP_011054833.1\|496516_497209_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_002991890.1\|497205_498210_+	sensor histidine kinase	NA	NA	NA	NA
WP_010922536.1\|498202_498844_+	response regulator transcription factor	NA	NA	NA	NA
WP_011285657.1\|498880_500281_+	Cof-type HAD-IIB family hydrolase	A0A1V0S9I2	Catovirus	2.7e-25	42.9
499629:499646	attL	NA	NA	NA	NA
WP_002991882.1\|500280_500658_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_010922535.1\|500675_501617_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	3.5e-130	77.6
WP_029714065.1\|501744_502377_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	3.2e-63	54.3
WP_010922534.1\|502432_503758_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	1.0e-114	50.6
WP_002983685.1\|503729_504395_+	ComF family protein	NA	NA	NA	NA
WP_002988974.1\|504474_505023_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_002983693.1\|512713_513247_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_009880741.1\|513326_514103_-	recombination regulator RecX	NA	NA	NA	NA
WP_011018152.1\|514250_515417_-\|integrase	tyrosine-type recombinase/integrase	C5J953	Streptococcus_phage	2.4e-80	42.4
WP_014635616.1\|515598_517020_-	DUF4041 domain-containing protein	M1PLF9	Streptococcus_phage	1.0e-136	74.1
WP_023605207.1\|517034_517421_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	1.9e-53	77.6
WP_011888679.1\|517404_517746_-	helix-turn-helix transcriptional regulator	J7KJZ4	Streptococcus_phage	1.2e-48	85.8
WP_014635614.1\|517943_518156_+	DNA-binding protein	J7KBP9	Streptococcus_phage	9.2e-31	95.7
WP_011888681.1\|518183_518903_+	phage antirepressor KilAC domain-containing protein	M1Q1T4	Streptococcus_phage	7.4e-88	70.3
WP_011284879.1\|519000_519240_-	hypothetical protein	NA	NA	NA	NA
WP_011054585.1\|519406_519592_+	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011888682.1\|519662_519914_+	hypothetical protein	A0A1P8VVV6	Streptococcus_phage	2.6e-40	97.6
WP_011017881.1\|519944_520082_+	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
WP_014635613.1\|520175_520937_+	replication initiator protein A	A0A097PBE7	Streptococcus_pyogenes_phage	7.5e-131	100.0
WP_011888684.1\|520923_521706_+	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	1.0e-143	97.3
WP_011285579.1\|521846_522200_+	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	2.8e-16	54.0
WP_011018143.1\|522180_522435_+	hypothetical protein	Q938N0	Temperate_phage	3.7e-42	98.8
WP_011018142.1\|522456_522939_+	siphovirus Gp157 family protein	Q938M9	Temperate_phage	8.2e-51	100.0
WP_046735269.1\|522939_523614_+	ERF family protein	Q938M8	Temperate_phage	1.5e-103	97.3
WP_011285575.1\|523606_524032_+	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	2.8e-55	82.3
WP_011106686.1\|524037_524241_+	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_011285574.1\|524240_524681_+	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	4.5e-80	97.9
WP_011284873.1\|524677_525034_+	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	2.9e-61	100.0
WP_002995955.1\|525275_525512_+	DUF3310 domain-containing protein	A0A097PAQ7	Streptococcus_pyogenes_phage	2.4e-40	100.0
WP_002995952.1\|525508_525679_+	hypothetical protein	Q938M0	Temperate_phage	7.9e-09	87.1
WP_011018134.1\|525675_525960_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	8.9e-37	87.2
WP_011888685.1\|525961_526594_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.1e-85	68.6
WP_011888686.1\|526598_527078_+	DUF1642 domain-containing protein	A0A141E0J6	Streptococcus_phage	6.5e-24	41.9
526810:526827	attR	NA	NA	NA	NA
WP_002987493.1\|527074_527245_+	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
WP_011888687.1\|527528_527963_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	1.7e-71	94.4
WP_010922073.1\|530105_530582_+	hypothetical protein	Q938L4	Temperate_phage	4.9e-48	68.4
WP_010922074.1\|530664_531876_+\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
WP_010922075.1\|531889_533392_+\|portal	phage portal protein	Q938L2	Temperate_phage	5.9e-281	99.6
WP_029714379.1\|533396_534890_+\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	3.4e-212	79.6
WP_010922077.1\|534889_535117_+	hypothetical protein	NA	NA	NA	NA
WP_011888689.1\|535203_535470_+	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_011888690.1\|535595_536210_+	hypothetical protein	Q938K8	Temperate_phage	3.8e-93	93.1
WP_010922080.1\|536213_537032_+\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_011888692.1\|537085_537502_+	hypothetical protein	Q938K7	Temperate_phage	9.6e-56	98.2
WP_011888693.1\|537491_537824_+	hypothetical protein	Q79S86	Temperate_phage	6.2e-58	99.1
WP_010922083.1\|537823_538180_+	hypothetical protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_011888694.1\|538176_538575_+\|capsid	phage capsid protein	Q79S87	Temperate_phage	6.5e-70	98.5
WP_011018120.1\|538574_539036_+	hypothetical protein	Q938K6	Temperate_phage	1.9e-60	78.8
WP_011888695.1\|539079_539514_+	hypothetical protein	Q938K5	Temperate_phage	4.2e-70	97.9
WP_011888696.1\|539517_540099_+	hypothetical protein	Q938K4	Temperate_phage	1.0e-100	94.3
WP_029714384.1\|540088_543349_+	tape measure protein	Q938K3	Temperate_phage	0.0e+00	99.1
WP_011888697.1\|543345_544062_+\|tail	phage tail family protein	Q938K2	Temperate_phage	1.2e-135	99.2
WP_014635605.1\|544058_546203_+\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	95.1
WP_011017589.1\|546199_547210_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	7.8e-136	75.8
WP_014635603.1\|547222_549109_+	gp58-like family protein	Q938J9	Temperate_phage	2.0e-217	84.6
WP_002983467.1\|549120_549552_+	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_011888699.1\|549554_550187_+	hypothetical protein	Q938J7	Temperate_phage	3.2e-42	48.6
WP_011184730.1\|550196_550652_+\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	2.3e-63	81.5
WP_011888700.1\|550763_551969_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.8e-203	83.5
WP_011017840.1\|552108_552633_+	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_011888701.1\|552620_553487_+	DUF334 domain-containing protein	Q938J2	Temperate_phage	1.1e-133	99.7
WP_011017966.1\|553536_553971_-	hypothetical protein	NA	NA	NA	NA
WP_011285611.1\|554241_555042_-	streptodornase Sda3	NA	NA	NA	NA
WP_011184907.1\|555279_555462_+	hypothetical protein	A3F673	Streptococcus_phage	4.4e-21	83.3
WP_010922532.1\|555652_557008_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	1.7e-72	32.7

DBSCAN-SWA_3

637287 : 695149

Streptococcus_phage(64.15%)

integrase,tRNA,holin,portal,terminase,tail,protease,capsid

attL 659594:659613|attR 692926:692945

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010922491.1\|637287_640089_+\|tRNA	isoleucine--tRNA ligase	H2EEZ0	Moumouvirus	2.5e-70	27.0
WP_010922490.1\|640353_640656_-	DUF1827 family protein	NA	NA	NA	NA
WP_002989103.1\|640706_641162_-	NUDIX hydrolase	NA	NA	NA	NA
WP_010922489.1\|641289_643572_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	6.3e-125	39.7
WP_002983885.1\|643869_644100_+	YkuJ family protein	NA	NA	NA	NA
WP_002983887.1\|644226_644913_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_010922488.1\|644912_645647_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.2e-34	38.4
WP_010922487.1\|645795_647205_+	deoxyribodipyrimidine photo-lyase	A0A1V0SGL1	Hokovirus	1.5e-60	32.8
WP_002989112.1\|647382_649077_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.6e-128	42.4
WP_010922486.1\|649284_650139_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	2.0e-39	39.8
WP_002992349.1\|650291_651632_+	exodeoxyribonuclease VII large subunit	A0A1V0SIT1	Klosneuvirus	8.2e-40	30.9
WP_002983901.1\|651609_651825_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_003056941.1\|651824_652697_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_003056952.1\|652689_653517_+	TlyA family rRNA (cytidine-2'-O)-methyltransferase	NA	NA	NA	NA
WP_002983907.1\|653503_653974_+	arginine repressor	NA	NA	NA	NA
WP_010922485.1\|653995_655657_+	DNA repair protein RecN	NA	NA	NA	NA
WP_011285633.1\|655828_656770_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002983913.1\|656985_657837_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7
WP_002992620.1\|657829_658672_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_010922482.1\|658649_659237_+	YpmS family protein	NA	NA	NA	NA
WP_002983920.1\|659335_659611_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
659594:659613	attL	NA	NA	NA	NA
WP_003051793.1\|659699_660842_-\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_010922481.1\|660965_661484_-	restriction endonuclease	E8ZDN5	Streptococcus_phage	9.2e-32	45.9
WP_010922480.1\|661495_662251_-	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	2.8e-77	60.8
WP_010922479.1\|662451_662664_+	helix-turn-helix transcriptional regulator	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
WP_010922478.1\|662933_663245_+	excisionase	A0A1S5SA25	Streptococcus_phage	5.3e-43	77.7
WP_010922477.1\|663246_663432_+	hypothetical protein	Q938N3	Temperate_phage	1.3e-20	83.6
WP_011017564.1\|663935_664322_+	DnaD domain-containing protein	Q938N2	Temperate_phage	8.1e-25	51.9
WP_002985387.1\|664302_664536_+	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_011017992.1\|664532_664673_+	hypothetical protein	NA	NA	NA	NA
WP_011017565.1\|664681_664888_+	hypothetical protein	NA	NA	NA	NA
WP_002988359.1\|664943_665273_+	hypothetical protein	J7KGX3	Streptococcus_phage	2.1e-45	83.5
WP_011285626.1\|665275_666205_+	recombinase RecT	M1NRN6	Streptococcus_phage	1.1e-91	72.2
WP_011285625.1\|666201_666999_+	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	6.0e-131	84.5
WP_011285624.1\|667008_667176_+	hypothetical protein	A0A1S5SEF3	Streptococcus_phage	3.3e-07	51.9
WP_020837403.1\|667353_667695_+	hypothetical protein	M1NS23	Streptococcus_phage	1.1e-12	38.7
WP_002988366.1\|667691_668204_+	hypothetical protein	Q708P9	Streptococcus_phage	2.3e-67	78.0
WP_002988369.1\|668287_668557_+	hypothetical protein	A7J287	Streptococcus_phage	9.6e-25	71.9
WP_010922070.1\|668558_669194_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.0e-89	69.4
WP_010922470.1\|669461_669881_+	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	8.7e-57	79.9
WP_010922469.1\|669989_670334_+	HNH endonuclease	M1Q0W7	Streptococcus_phage	5.5e-41	68.5
WP_002994106.1\|670482_670839_+	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_010922468.1\|670835_672104_+\|portal	phage portal protein	M1PFL4	Streptococcus_phage	2.2e-188	75.6
WP_010922467.1\|672096_673590_+	hypothetical protein	M1Q184	Streptococcus_phage	2.0e-87	55.0
WP_010922466.1\|673595_673820_+	hypothetical protein	NA	NA	NA	NA
WP_015055972.1\|673869_674049_+	hypothetical protein	NA	NA	NA	NA
WP_010922464.1\|674041_674308_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	7.3e-33	86.4
WP_011285619.1\|674417_675833_+\|terminase	terminase	A0A0B5A091	Streptococcus_phage	2.9e-213	74.2
WP_010922462.1\|675913_676375_+	DUF4355 domain-containing protein	M1Q1L0	Streptococcus_phage	4.5e-38	53.2
WP_010922461.1\|676399_677311_+\|capsid	phage major capsid protein	M1PFL0	Streptococcus_phage	9.9e-114	67.3
WP_010922460.1\|677310_677511_+	hypothetical protein	NA	NA	NA	NA
WP_010922459.1\|677520_677943_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	3.7e-47	70.8
WP_011285617.1\|677902_678241_+	hypothetical protein	M1PFF8	Streptococcus_phage	2.2e-42	70.3
WP_010922457.1\|678233_678470_+	hypothetical protein	A0A0B5A7G2	Streptococcus_phage	2.5e-21	71.4
WP_000573598.1\|678470_678806_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_010922456.1\|678817_679411_+\|tail	tail protein	M1PKG8	Streptococcus_phage	3.5e-59	62.5
WP_010922455.1\|679421_679685_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.0e-18	55.8
WP_010922454.1\|679699_680071_+	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	2.9e-35	62.4
WP_010922453.1\|680070_682428_+	hypothetical protein	M1NRG5	Streptococcus_phage	6.5e-141	50.6
WP_010922452.1\|682424_683120_+	hypothetical protein	A0A1B1P761	Bacillus_phage	7.6e-05	29.6
WP_010922451.1\|683116_685075_+\|tail	phage tail protein	M1PKG3	Streptococcus_phage	5.3e-96	49.2
WP_023079488.1\|685074_686076_+	hyaluronidase HylP	Q938K0	Temperate_phage	2.3e-127	71.6
WP_010922449.1\|686090_687875_+	hypothetical protein	Q938J9	Temperate_phage	6.3e-96	47.5
WP_010922448.1\|687886_688318_+	DUF1617 family protein	Q938J8	Temperate_phage	3.8e-71	97.9
WP_010922447.1\|688320_688938_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.0e-77	88.8
WP_002987582.1\|688947_689223_+	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_003058873.1\|689219_689447_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_010922446.1\|689562_690768_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	5.9e-207	84.3
WP_011017966.1\|690837_691272_-	hypothetical protein	NA	NA	NA	NA
WP_011285611.1\|691544_692345_-	streptodornase Sda3	NA	NA	NA	NA
WP_029714291.1\|692573_692756_+	hypothetical protein	A3F673	Streptococcus_phage	1.7e-20	80.0
WP_029714293.1\|693286_695149_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.6e-89	33.7
692926:692945	attR	NA	NA	NA	NA

DBSCAN-SWA_4

813249 : 861364

Streptococcus_pyogenes_phage(70.18%)

integrase,holin,portal,terminase,tail,capsid

attL 816616:816675|attR 854948:855043

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010922381.1\|813249_815514_+	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
WP_002989605.1\|815770_816391_-	DUF3862 domain-containing protein	NA	NA	NA	NA
816616:816675	attL	NA	NA	NA	NA
WP_011054595.1\|816753_817842_-\|integrase	site-specific integrase	A0A097PAS9	Streptococcus_pyogenes_phage	4.7e-203	99.2
WP_011285585.1\|817962_818856_-	hypothetical protein	A0A1I9LJQ0	Stx_converting_phage	1.2e-68	47.5
WP_011285584.1\|818891_819716_-	helix-turn-helix transcriptional regulator	A0A097PBE5	Streptococcus_pyogenes_phage	1.2e-131	91.6
WP_011285583.1\|820072_820231_+	hypothetical protein	A0A097PAP2	Streptococcus_pyogenes_phage	4.8e-24	100.0
WP_011284882.1\|820260_820860_-	hypothetical protein	A0A097PAT4	Streptococcus_pyogenes_phage	3.1e-108	100.0
WP_011284881.1\|820913_821123_+	hypothetical protein	A0A097PAQ9	Streptococcus_pyogenes_phage	1.7e-32	100.0
WP_011054589.1\|821111_821498_-	hypothetical protein	A0A097PAT1	Streptococcus_pyogenes_phage	1.2e-65	100.0
WP_002992770.1\|821571_821772_+	helix-turn-helix transcriptional regulator	A0A141E205	Streptococcus_phage	2.7e-08	59.6
WP_011017885.1\|821881_822091_-	hypothetical protein	NA	NA	NA	NA
WP_011017884.1\|822221_822731_-	hypothetical protein	NA	NA	NA	NA
WP_029714276.1\|822785_823049_+	hypothetical protein	A0A097PAP6	Streptococcus_pyogenes_phage	3.6e-40	98.9
WP_011054584.1\|823085_823382_+	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	2.1e-49	100.0
WP_023610888.1\|823528_823843_+	helix-turn-helix transcriptional regulator	A0A1P8VVN6	Streptococcus_phage	2.7e-50	95.2
WP_009881060.1\|823856_824687_+	phage replisome organizer N-terminal domain-containing protein	A0A1S5S918	Streptococcus_phage	6.4e-67	54.7
WP_011285581.1\|824673_825456_+	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	3.9e-143	96.9
WP_011285579.1\|825596_825950_+	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	2.8e-16	54.0
WP_011018143.1\|825930_826185_+	hypothetical protein	Q938N0	Temperate_phage	3.7e-42	98.8
WP_011018142.1\|826206_826689_+	siphovirus Gp157 family protein	Q938M9	Temperate_phage	8.2e-51	100.0
WP_029714396.1\|826689_827364_+	ERF family protein	Q938M8	Temperate_phage	3.1e-104	97.8
WP_011285575.1\|827356_827782_+	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	2.8e-55	82.3
WP_011106686.1\|827787_827991_+	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_011285574.1\|827990_828431_+	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	4.5e-80	97.9
WP_011284873.1\|828427_828784_+	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	2.9e-61	100.0
WP_011018133.1\|829132_829765_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.3e-85	68.6
WP_011285572.1\|829767_830292_+	DUF1642 domain-containing protein	J7KK91	Streptococcus_phage	2.3e-38	51.1
WP_011018131.1\|830288_830555_+	hypothetical protein	NA	NA	NA	NA
WP_011054810.1\|830840_831275_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	2.2e-71	94.4
WP_011285571.1\|831884_832265_+	hypothetical protein	A0A097PAR5	Streptococcus_pyogenes_phage	1.0e-64	100.0
WP_009880266.1\|832254_833529_+\|terminase	PBSX family phage terminase large subunit	A0A097PAV9	Streptococcus_pyogenes_phage	1.1e-251	100.0
WP_029714009.1\|833528_834854_+\|portal	phage portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	2.1e-237	97.2
WP_011285569.1\|834822_835731_+\|capsid	minor capsid protein	A0A097PBF2	Streptococcus_pyogenes_phage	6.7e-86	98.2
WP_011285568.1\|835737_836007_+	hypothetical protein	Q938K9	Temperate_phage	5.6e-33	85.2
WP_009880262.1\|836251_836821_+	DUF4355 domain-containing protein	A0A097PAW3	Streptococcus_pyogenes_phage	8.5e-71	98.4
WP_009880261.1\|836839_837730_+	hypothetical protein	A0A097PAW2	Streptococcus_pyogenes_phage	8.6e-86	99.4
WP_009880260.1\|837742_838036_+	Rho termination factor N-terminal domain-containing protein	A0A097PBF3	Streptococcus_pyogenes_phage	2.0e-47	100.0
WP_029714010.1\|838049_838388_+	hypothetical protein	A0A097PAS2	Streptococcus_pyogenes_phage	5.2e-52	98.2
WP_011285567.1\|838384_838696_+	hypothetical protein	A0A097PAW7	Streptococcus_pyogenes_phage	1.0e-49	98.1
WP_009880257.1\|838692_839088_+	hypothetical protein	A0A097PAT9	Streptococcus_pyogenes_phage	1.8e-59	100.0
WP_009880256.1\|839089_839500_+	DUF5072 family protein	A0A097PAW5	Streptococcus_pyogenes_phage	1.4e-70	100.0
WP_009880255.1\|839511_840018_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	2.6e-79	100.0
WP_009880254.1\|840030_840348_+	hypothetical protein	A0A097PAS6	Streptococcus_pyogenes_phage	4.9e-52	100.0
WP_009880253.1\|840320_840779_+	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	2.3e-82	100.0
WP_011054802.1\|840771_842577_+\|tail	tail protein	A0A097PAU2	Streptococcus_pyogenes_phage	8.8e-263	99.7
WP_009880250.1\|842577_844062_+\|tail	phage tail family protein	A0A097PAW9	Streptococcus_pyogenes_phage	4.3e-292	99.8
WP_011285566.1\|844062_847503_+\|tail	phage tail protein	A0A097PBF5	Streptococcus_pyogenes_phage	0.0e+00	98.7
WP_015055954.1\|847507_849370_+	hypothetical protein	A0A097PAT0	Streptococcus_pyogenes_phage	0.0e+00	99.4
WP_011285564.1\|849380_849728_+	DUF1366 domain-containing protein	A0A097PAX5	Streptococcus_pyogenes_phage	6.5e-58	99.1
WP_015055952.1\|849877_850201_+	hypothetical protein	A0A097PAX2	Streptococcus_pyogenes_phage	7.7e-53	100.0
WP_011285562.1\|850200_850533_+\|holin	phage holin	A0A097PBF6	Streptococcus_pyogenes_phage	7.4e-51	99.1
WP_011285561.1\|850534_851299_+	CHAP domain-containing protein	A0A097PAT3	Streptococcus_pyogenes_phage	8.0e-149	98.4
WP_011054796.1\|851310_851913_+	hypothetical protein	A0A097PAX9	Streptococcus_pyogenes_phage	7.8e-91	98.8
WP_011054795.1\|851923_852697_+	hypothetical protein	A0A097PAV0	Streptococcus_pyogenes_phage	3.9e-135	100.0
WP_009880241.1\|852706_852928_+	hypothetical protein	A0A097PAX7	Streptococcus_pyogenes_phage	2.5e-18	84.5
WP_009880240.1\|852927_853587_+	hypothetical protein	A0A097PBF7	Streptococcus_pyogenes_phage	8.5e-123	100.0
WP_009880239.1\|853708_854464_-	streptococcal pyrogenic exotoxin SpeA	A0A097PAT7	Streptococcus_pyogenes_phage	2.2e-143	100.0
WP_011285559.1\|854684_854873_+	hypothetical protein	J7KIW4	Streptococcus_phage	3.4e-21	82.3
WP_011285558.1\|855463_856078_+	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	1.1e-50	52.3
854948:855043	attR	NA	NA	NA	NA
WP_010922378.1\|856204_856990_-	hypothetical protein	NA	NA	NA	NA
WP_002984437.1\|856999_857698_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
WP_010922377.1\|857697_858069_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010922376.1\|858253_861364_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	3.7e-120	29.9

DBSCAN-SWA_5

1038039 : 1117614

Streptococcus_phage(87.76%)

transposase,integrase,tRNA,holin,portal,terminase,tail,protease,capsid

attL 1058971:1058990|attR 1103735:1103754

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010922268.1\|1038039_1039416_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_010922267.1\|1039483_1040893_-	dipeptidase PepV	NA	NA	NA	NA
WP_002989923.1\|1041017_1041620_-	nitroreductase family protein	NA	NA	NA	NA
WP_010922266.1\|1041804_1043601_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_010922265.1\|1043702_1045100_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_011285513.1\|1045194_1045884_-	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_010922263.1\|1045899_1046466_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_015055942.1\|1047244_1048291_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_010922260.1\|1048284_1049073_-	response regulator transcription factor	NA	NA	NA	NA
WP_011285511.1\|1049076_1050726_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	8.0e-13	33.3
WP_002989931.1\|1050861_1051689_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_002984844.1\|1051685_1052495_-	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_002984845.1\|1052511_1053003_-	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_002989935.1\|1053021_1053447_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_010922256.1\|1053653_1054673_-	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_010922255.1\|1054787_1055225_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_029714016.1\|1055410_1056229_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_010922253.1\|1056486_1058319_-	elongation factor 4	A0A2K9L2P9	Tupanvirus	2.2e-19	41.0
1058971:1058990	attL	NA	NA	NA	NA
WP_029714017.1\|1059072_1059255_-	hypothetical protein	A3F673	Streptococcus_phage	1.0e-17	71.7
WP_011054450.1\|1059453_1059663_-	helix-turn-helix transcriptional regulator	A3F668	Streptococcus_phage	1.2e-30	100.0
WP_011054448.1\|1060103_1060355_+	hypothetical protein	A3F666	Streptococcus_phage	2.8e-42	96.4
WP_011054447.1\|1060618_1060858_+	hypothetical protein	NA	NA	NA	NA
WP_011054446.1\|1060915_1061272_+	hypothetical protein	NA	NA	NA	NA
WP_029714018.1\|1061387_1062593_-	glucosaminidase domain-containing protein	A7J2B5	Streptococcus_phage	5.0e-198	82.0
WP_029714020.1\|1062715_1062943_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.2e-30	97.3
WP_011017397.1\|1062939_1063212_-	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_046735270.1\|1063223_1063862_-	hypothetical protein	A3F662	Streptococcus_phage	2.0e-44	52.7
WP_002988448.1\|1063864_1064293_-	DUF1617 family protein	Q938J8	Temperate_phage	8.1e-58	84.3
WP_011017395.1\|1064304_1066209_-	gp58-like family protein	Q938J9	Temperate_phage	1.1e-210	83.7
WP_011017394.1\|1066218_1067226_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	9.9e-115	64.9
WP_029713950.1\|1067222_1069274_-\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	85.2
WP_029713951.1\|1069270_1070041_-\|tail	phage tail family protein	A3F655	Streptococcus_phage	1.4e-129	87.9
WP_029713952.1\|1070053_1074154_-\|tail	phage tail tape measure protein	A3F654	Streptococcus_phage	0.0e+00	76.5
WP_029713954.1\|1074378_1074681_-	hypothetical protein	A3F652	Streptococcus_phage	2.4e-48	96.0
WP_029713955.1\|1074776_1075361_-\|tail	tail protein	A3F651	Streptococcus_phage	6.2e-93	90.2
WP_029713956.1\|1075372_1075753_-	hypothetical protein	A3F650	Streptococcus_phage	8.2e-62	97.6
WP_011017387.1\|1075745_1076144_-	HK97 gp10 family phage protein	A3F649	Streptococcus_phage	2.9e-70	100.0
WP_029713957.1\|1076145_1076508_-	hypothetical protein	A3F648	Streptococcus_phage	1.6e-59	95.8
WP_029713958.1\|1076500_1076809_-	hypothetical protein	A3F647	Streptococcus_phage	1.4e-43	92.2
WP_164875336.1\|1076808_1076982_-	hypothetical protein	A3F646	Streptococcus_phage	1.9e-21	91.2
WP_029713959.1\|1076992_1078126_-\|capsid	phage major capsid protein	A3F645	Streptococcus_phage	1.3e-200	96.0
WP_029713960.1\|1078142_1078949_-\|protease	Clp protease ClpP	A3F644	Streptococcus_phage	3.9e-146	97.8
WP_027970293.1\|1078929_1080117_-\|portal	phage portal protein	A3F643	Streptococcus_phage	2.1e-220	97.5
WP_029713961.1\|1080297_1082028_-\|terminase	terminase large subunit	A3F641	Streptococcus_phage	0.0e+00	97.4
WP_029713962.1\|1082040_1082358_-\|terminase	P27 family phage terminase small subunit	A3F640	Streptococcus_phage	1.3e-49	99.0
WP_029713963.1\|1082500_1082806_-	HNH endonuclease	A3F639	Streptococcus_phage	5.0e-54	97.0
WP_029713964.1\|1082798_1083185_-	hypothetical protein	A3F638	Streptococcus_phage	3.6e-65	93.0
WP_029713966.1\|1083426_1083672_-	hypothetical protein	NA	NA	NA	NA
WP_029713967.1\|1083695_1083992_-	hypothetical protein	NA	NA	NA	NA
WP_029713968.1\|1084146_1084722_-\|integrase	site-specific integrase	A3F636	Streptococcus_phage	2.7e-101	94.8
WP_027970299.1\|1084879_1085281_-	hypothetical protein	A3F635	Streptococcus_phage	3.4e-66	93.2
WP_029713969.1\|1085283_1085628_-	helix-turn-helix transcriptional regulator	A3F633	Streptococcus_phage	1.4e-49	95.0
WP_029713970.1\|1085624_1085903_-	hypothetical protein	A3F632	Streptococcus_phage	9.6e-44	96.7
WP_029713971.1\|1085916_1086309_-	single-stranded DNA-binding protein	A0A1P8VVS8	Streptococcus_phage	5.3e-48	71.7
WP_003057301.1\|1086305_1086527_-	hypothetical protein	NA	NA	NA	NA
WP_029713972.1\|1086519_1086852_-	hypothetical protein	A0A1S5SCX1	Streptococcus_phage	5.9e-32	54.6
WP_029713973.1\|1086844_1087084_-	DUF3310 domain-containing protein	A3F631	Streptococcus_phage	2.6e-37	94.8
WP_080033899.1\|1087206_1087500_-	DUF1372 family protein	A0A1X9I624	Streptococcus_phage	1.1e-21	50.5
WP_093974717.1\|1087508_1088000_-	hypothetical protein	A0A1P8VVP1	Streptococcus_phage	1.2e-70	79.8
WP_153276856.1\|1087986_1088151_-	hypothetical protein	NA	NA	NA	NA
WP_029713977.1\|1088161_1088392_-	hypothetical protein	C5J991	Streptococcus_phage	1.0e-14	52.8
WP_029713978.1\|1088391_1089213_-	ATP-binding protein	A0A1P8VVV9	Streptococcus_phage	1.2e-147	94.9
WP_029713979.1\|1089213_1089960_-	conserved phage C-terminal domain-containing protein	A0A1P8VVR3	Streptococcus_phage	3.7e-135	97.2
WP_029713980.1\|1089946_1091293_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	2.3e-207	84.0
WP_029713981.1\|1091279_1091468_-	hypothetical protein	NA	NA	NA	NA
WP_022554795.1\|1091622_1091880_-	hypothetical protein	A3F618	Streptococcus_phage	7.0e-41	95.3
WP_029713982.1\|1092136_1092343_+	hypothetical protein	NA	NA	NA	NA
WP_029713983.1\|1092339_1092552_-	hypothetical protein	NA	NA	NA	NA
WP_029713984.1\|1092626_1093346_-	ORF6C domain-containing protein	A3F617	Streptococcus_phage	1.6e-106	79.5
WP_029713985.1\|1093388_1093616_-	hypothetical protein	A0A141E1R7	Streptococcus_phage	1.2e-12	57.3
WP_029713986.1\|1093854_1094436_-	hypothetical protein	NA	NA	NA	NA
WP_022554802.1\|1094610_1094757_-	hypothetical protein	A0A1S5S7K5	Streptococcus_phage	2.1e-05	60.4
WP_029713987.1\|1094915_1095671_+	helix-turn-helix transcriptional regulator	M1NS52	Streptococcus_phage	4.3e-78	64.4
WP_029713988.1\|1096066_1097263_+\|integrase	tyrosine-type recombinase/integrase	A3F610	Streptococcus_phage	1.5e-223	96.7
WP_010922252.1\|1097470_1098133_-	type II-A CRISPR-associated protein Csn2	NA	NA	NA	NA
WP_002989951.1\|1098122_1098464_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_002989953.1\|1098460_1099330_-	type II CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_011285506.1\|1099329_1103436_-	type II CRISPR RNA-guided endonuclease Cas9	NA	NA	NA	NA
WP_010922250.1\|1103915_1104548_-	TIGR01906 family membrane protein	NA	NA	NA	NA
1103735:1103754	attR	NA	NA	NA	NA
WP_010922249.1\|1104547_1105312_-	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_011285504.1\|1105311_1106064_-	acyl-[acyl-carrier-protein] thioesterase	NA	NA	NA	NA
WP_010922247.1\|1106073_1107204_-	oxygen-independent coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_010922246.1\|1107266_1107908_-	hypothetical protein	NA	NA	NA	NA
WP_010922245.1\|1108041_1109397_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_002984857.1\|1109450_1110407_-	YbbR-like domain-containing protein	NA	NA	NA	NA
WP_010922244.1\|1110403_1111255_-	TIGR00159 family protein	NA	NA	NA	NA
WP_011285501.1\|1111361_1112705_+	Mur ligase family protein	NA	NA	NA	NA
WP_010922242.1\|1112704_1113496_+	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_002992006.1\|1113604_1114594_-	lipoate--protein ligase	A0A2H4UVX5	Bodo_saltans_virus	8.2e-13	25.2
WP_010922241.1\|1114826_1117244_+	polysaccharide lyase 8 family protein	NA	NA	NA	NA
WP_111705325.1\|1117470_1117614_-\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

1242134 : 1252737

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011285480.1\|1242134_1243277_-	cysteine desulfurase	H7BUW1	unidentified_phage	7.8e-15	31.7
WP_010922142.1\|1243511_1243952_+	membrane protein	NA	NA	NA	NA
WP_002990257.1\|1243981_1245250_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_010922141.1\|1245337_1246690_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	4.5e-30	24.0
WP_010922140.1\|1246910_1247252_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	41.1
WP_010922139.1\|1247312_1248479_-	chorismate synthase	A0A291AU41	Pandoravirus	1.8e-38	34.4
WP_002985140.1\|1248572_1249259_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002985142.1\|1249255_1250419_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_029713995.1\|1250526_1252737_+	LTA synthase family protein	W6LM83	Streptococcus_phage	6.5e-268	68.9

DBSCAN-SWA_7

1312659 : 1400961

Streptococcus_phage(59.68%)

head,tRNA,portal,terminase,tail,protease,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002985272.1\|1312659_1313331_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_029713999.1\|1313305_1314664_-	YcaO-like family protein	NA	NA	NA	NA
WP_010922109.1\|1314683_1315742_-	streptolysin associated protein SagC	NA	NA	NA	NA
WP_010922108.1\|1315738_1316689_-	streptolysin S biosynthesis dehydrogenase SagB	NA	NA	NA	NA
WP_002985285.1\|1316910_1317072_-	TOMM family cytolysin streptolysin S	NA	NA	NA	NA
WP_029714000.1\|1317936_1324116_-	DUF1542 domain-containing protein	NA	NA	NA	NA
WP_002985288.1\|1327905_1329213_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
WP_002990451.1\|1329439_1329898_+	YueI family protein	W6LLD2	Streptococcus_phage	1.8e-18	39.1
WP_029714002.1\|1330029_1331754_-	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_010922104.1\|1332121_1334074_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.5e-143	46.3
WP_011285465.1\|1334074_1334644_-	hydrolase	NA	NA	NA	NA
WP_002985298.1\|1335646_1335994_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_011285464.1\|1336108_1337371_-	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	8.4e-95	50.5
WP_010922101.1\|1337363_1337648_-	chorismate mutase	NA	NA	NA	NA
WP_002985303.1\|1337823_1338273_-	flavodoxin	NA	NA	NA	NA
WP_010922100.1\|1338666_1339608_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_002985307.1\|1339722_1339983_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_011285463.1\|1340079_1341279_-	SIS domain-containing protein	NA	NA	NA	NA
WP_010922098.1\|1341297_1342020_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_029714003.1\|1342167_1343715_-	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_029714004.1\|1343866_1345285_-	C69 family dipeptidase	NA	NA	NA	NA
WP_029714005.1\|1345562_1345802_+	hypothetical protein	NA	NA	NA	NA
WP_002986905.1\|1345841_1346315_+	hypothetical protein	A3F671	Streptococcus_phage	1.6e-78	92.3
WP_002986907.1\|1346316_1346673_+	hypothetical protein	NA	NA	NA	NA
WP_011017840.1\|1347595_1348120_-	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_046735271.1\|1348259_1349462_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	2.7e-228	94.8
WP_011184796.1\|1349574_1349760_-	hypothetical protein	Q938J5	Temperate_phage	6.6e-25	98.4
WP_011018110.1\|1349756_1350056_-	hypothetical protein	Q938J6	Temperate_phage	1.9e-42	93.8
WP_029714007.1\|1350066_1350684_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.0e-77	87.8
WP_011018112.1\|1350686_1351115_-	DUF1617 family protein	Q938J8	Temperate_phage	1.9e-54	78.6
WP_046735272.1\|1351126_1353013_-	gp58-like family protein	Q938J9	Temperate_phage	2.6e-209	82.6
WP_029714406.1\|1353025_1354045_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	8.3e-178	95.8
WP_046735273.1\|1354041_1356186_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	98.3
WP_014411854.1\|1356182_1356890_-\|tail	phage tail family protein	Q938K2	Temperate_phage	1.7e-92	71.1
WP_029714351.1\|1356889_1360813_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.0e-239	48.8
WP_014411856.1\|1360825_1360993_-	hypothetical protein	J7KBS0	Streptococcus_phage	2.9e-19	87.3
WP_014411857.1\|1361022_1361349_-	hypothetical protein	J7KK85	Streptococcus_phage	6.0e-37	73.1
WP_014411858.1\|1361401_1362010_-\|tail	phage major tail protein	J7KKC8	Streptococcus_phage	2.3e-74	70.5
WP_002985347.1\|1362026_1362452_-	hypothetical protein	J7KBZ9	Streptococcus_phage	5.0e-68	85.1
WP_021340627.1\|1362448_1362826_-	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.8e-45	73.6
WP_029714354.1\|1362822_1363170_-\|head	phage head closure protein	J7KJ42	Streptococcus_phage	2.1e-48	84.5
WP_021341088.1\|1363166_1363469_-\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	2.6e-42	87.8
WP_029714355.1\|1363613_1364798_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	2.3e-163	76.3
WP_029714356.1\|1364821_1365487_-\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	6.0e-92	77.7
WP_011017578.1\|1365464_1366685_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	6.9e-187	81.9
WP_002985363.1\|1366718_1366943_-	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_002985365.1\|1366935_1367106_-	hypothetical protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
WP_029714357.1\|1367102_1368857_-\|terminase	terminase large subunit	J7KKD1	Streptococcus_phage	0.0e+00	96.2
WP_002985368.1\|1368860_1369091_-	hypothetical protein	NA	NA	NA	NA
WP_002985371.1\|1369093_1369561_-\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_029714359.1\|1369728_1370070_-	HNH endonuclease	J7KH36	Streptococcus_phage	9.6e-54	89.8
WP_001132273.1\|1370305_1370491_+	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002987543.1\|1370542_1370920_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_029714361.1\|1371045_1371957_-	DNA adenine methylase	A0A126HDT5	Lactococcus_phage	4.3e-101	64.5
WP_011017866.1\|1372511_1372952_-	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
WP_046735274.1\|1373224_1373860_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.0e-84	66.5
WP_029714363.1\|1374257_1374461_-	hypothetical protein	NA	NA	NA	NA
WP_164875335.1\|1374479_1374638_-	hypothetical protein	NA	NA	NA	NA
WP_029714365.1\|1374640_1374868_-	hypothetical protein	A0A1S5S8R7	Streptococcus_phage	6.2e-09	47.8
WP_029714366.1\|1374871_1375156_-	hypothetical protein	A3F628	Streptococcus_phage	3.6e-38	90.4
WP_020837669.1\|1375152_1375566_-	hypothetical protein	Q938M1	Temperate_phage	4.9e-36	65.2
WP_002990061.1\|1375562_1375757_-	hypothetical protein	A3F626	Streptococcus_phage	9.7e-11	86.5
WP_029714370.1\|1375743_1376256_-	hypothetical protein	Q708P9	Streptococcus_phage	3.4e-63	74.4
WP_020837403.1\|1376252_1376594_-	hypothetical protein	M1NS23	Streptococcus_phage	1.1e-12	38.7
WP_020837672.1\|1376770_1377568_-	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	3.4e-126	82.3
WP_010922473.1\|1377560_1377761_-	hypothetical protein	NA	NA	NA	NA
WP_010922474.1\|1377757_1378747_-	recombinase RecT	A0A286QMX3	Streptococcus_phage	5.8e-59	44.2
WP_010922475.1\|1378746_1379079_-	hypothetical protein	J7KGX3	Streptococcus_phage	2.2e-42	78.7
WP_002988357.1\|1379134_1379341_-	hypothetical protein	NA	NA	NA	NA
WP_002988354.1\|1379349_1379490_-	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	3.4e-05	54.5
WP_010922205.1\|1379486_1379720_-	hypothetical protein	Q938N1	Temperate_phage	2.8e-36	96.1
WP_002990076.1\|1379700_1380087_-	DnaD domain-containing protein	Q938N2	Temperate_phage	1.1e-24	47.3
WP_002985392.1\|1380569_1380755_-	hypothetical protein	Q938N3	Temperate_phage	2.0e-21	83.6
WP_002985395.1\|1380756_1380894_-	hypothetical protein	NA	NA	NA	NA
WP_011889039.1\|1380980_1381163_+	hypothetical protein	NA	NA	NA	NA
WP_029714046.1\|1381303_1382065_-	phage antirepressor KilAC domain-containing protein	A0A0C5AEJ9	Bacteriophage	3.6e-85	61.5
WP_002985407.1\|1382113_1382302_-	helix-turn-helix transcriptional regulator	A0A0B5A7F0	Streptococcus_phage	2.6e-13	63.3
WP_001008979.1\|1382353_1382995_+	hypothetical protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
WP_002985414.1\|1383093_1383252_-	hypothetical protein	J7KH24	Streptococcus_phage	7.1e-20	88.5
WP_002985417.1\|1383611_1384376_+	helix-turn-helix transcriptional regulator	E8ZDN4	Streptococcus_phage	2.0e-83	64.5
WP_002985420.1\|1384385_1384691_+	membrane protein	NA	NA	NA	NA
WP_029714044.1\|1384814_1386230_+	recombinase family protein	A5GZ62	Lactococcus_phage	7.9e-110	47.2
WP_002985428.1\|1386406_1387318_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.3e-105	64.7
WP_002985431.1\|1387314_1388292_-	YvcK family protein	A1IMD5	Streptococcus_phage	2.1e-138	74.2
WP_002985434.1\|1388288_1389179_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
WP_002985437.1\|1389592_1390939_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.1e-55	30.8
WP_002985439.1\|1390959_1392153_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_010922051.1\|1392487_1394989_-	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	1.3e-203	48.1
WP_010922050.1\|1396028_1396727_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.1e-77	62.4
WP_002990498.1\|1397036_1397966_-	ABC transporter permease	NA	NA	NA	NA
WP_002985455.1\|1397958_1398651_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	1.0e-30	35.6
WP_101485534.1\|1398669_1399768_-	peptide chain release factor 2	NA	NA	NA	NA
WP_015055933.1\|1399836_1400961_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA

DBSCAN-SWA_8

1464033 : 1470684

Streptococcus_phage(66.67%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029714029.1\|1464033_1464858_-	asparagine ligase	M1PB22	Moumouvirus	8.1e-22	33.1
WP_011285437.1\|1464881_1465220_-	Fic family protein	NA	NA	NA	NA
WP_011285436.1\|1465636_1465951_-	hypothetical protein	Q6DMT0	Streptococcus_phage	4.9e-20	64.5
WP_010922006.1\|1466016_1466469_-\|portal	phage portal protein	E4ZFM3	Streptococcus_phage	4.4e-62	84.9
WP_010922005.1\|1466573_1466846_-	hypothetical protein	E4ZFM1	Streptococcus_phage	1.2e-06	48.1
WP_011285435.1\|1466864_1467170_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002991611.1\|1467169_1467472_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_015055928.1\|1467526_1467703_-	prophage LambdaSa04	M1PSF2	Streptococcus_phage	3.2e-21	86.2
WP_160338849.1\|1467718_1468612_+	hypothetical protein	NA	NA	NA	NA
WP_010922001.1\|1468611_1468836_+	hypothetical protein	NA	NA	NA	NA
WP_010921999.1\|1469639_1470485_+	DUF2326 domain-containing protein	NA	NA	NA	NA
WP_002985621.1\|1470474_1470684_+	helix-turn-helix domain-containing protein	A0A2K5B263	Erysipelothrix_phage	1.3e-16	61.5

DBSCAN-SWA_9

1572999 : 1579033

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010921936.1\|1572999_1573827_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.4e-127	79.1
WP_011284536.1\|1573900_1574257_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-40	65.8
WP_010921934.1\|1574555_1575185_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_002985833.1\|1575231_1575624_-	hypothetical protein	NA	NA	NA	NA
WP_029714023.1\|1575650_1576514_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.5e-115	74.7
WP_002985838.1\|1576518_1576842_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_010921932.1\|1577246_1577486_-	hypothetical protein	NA	NA	NA	NA
WP_010921931.1\|1577504_1578380_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	7.7e-63	43.8
WP_010921930.1\|1578397_1579033_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.2e-65	63.4

Anti-CRISPR protein detection

Acr_ID: NZ_CP007537.1|WP_011054448.1|1060103_1060355_+|hypothetical-protein

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Acr_ID: NZ_CP007537.1|WP_011054447.1|1060618_1060858_+|hypothetical-protein

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Acr_ID: NZ_CP007537.1|WP_011054446.1|1060915_1061272_+|hypothetical-protein

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Acr_ID: NZ_CP007537.1|WP_029713985.1|1093388_1093616_-|hypothetical-protein

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Acr_ID: NZ_CP007537.1|WP_029713986.1|1093854_1094436_-|hypothetical-protein

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Acr_ID: NZ_CP007537.1|WP_022554802.1|1094610_1094757_-|hypothetical-protein

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Acr_ID: NZ_CP007537.1|WP_029714005.1|1345562_1345802_+|hypothetical-protein

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Acr_ID: NZ_CP007537.1|WP_001008979.1|1382353_1382995_+|hypothetical-protein

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Acr_ID: NZ_CP007537.1|WP_002985414.1|1383093_1383252_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP007537.1|WP_011054448.1|1060103_1060355_+|hypothetical-protein

1060103_1060355_+

83 aa aa

1038039-1117614

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	1065475-1065507	1

1. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1065475-1065507, mismatch: 1

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

NZ_CP007537.1|WP_011054447.1|1060618_1060858_+|hypothetical-protein

1060618_1060858_+

79 aa aa

1038039-1117614

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	1065475-1065507	1

1. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1065475-1065507, mismatch: 1

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

NZ_CP007537.1|WP_011054446.1|1060915_1061272_+|hypothetical-protein

1060915_1061272_+

118 aa aa

1038039-1117614

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	1065475-1065507	1

1. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1065475-1065507, mismatch: 1

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

NZ_CP007537.1|WP_029713985.1|1093388_1093616_-|hypothetical-protein

1093388_1093616_-

75 aa aa

1038039-1117614

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	1065475-1065507	1

1. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1065475-1065507, mismatch: 1

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

NZ_CP007537.1|WP_029713986.1|1093854_1094436_-|hypothetical-protein

1093854_1094436_-

193 aa aa

1038039-1117614

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	1065475-1065507	1

1. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1065475-1065507, mismatch: 1

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

NZ_CP007537.1|WP_022554802.1|1094610_1094757_-|hypothetical-protein

1094610_1094757_-

48 aa aa

1038039-1117614

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.4\|598692\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598692-598724	33	1065475-1065507	1

1. spacer 1.4|598692|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1065475-1065507, mismatch: 1

tgtccgcataccttgatttgagcgagtaaactc	CRISPR spacer
tgtccgcatgccttgatttgagcgagtaaactc	Protospacer
*********.***********************

NZ_CP007537.1|WP_029714005.1|1345562_1345802_+|hypothetical-protein

1345562_1345802_+

79 aa aa

1312659-1400961

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	1364620-1364652	0

1. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1364620-1364652, mismatch: 0

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggtttgcttta	Protospacer
*********************************

NZ_CP007537.1|WP_001008979.1|1382353_1382995_+|hypothetical-protein

1382353_1382995_+

213 aa aa

1312659-1400961

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	1364620-1364652	0

1. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1364620-1364652, mismatch: 0

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggtttgcttta	Protospacer
*********************************

NZ_CP007537.1|WP_002985414.1|1383093_1383252_-|hypothetical-protein

1383093_1383252_-

52 aa aa

1312659-1400961

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP007537_1	TypeI	1.2\|598561\|33\|NZ_CP007537\|PILER-CR,CRISPRCasFinder,CRT	598561-598593	33	1364620-1364652	0

1. spacer 1.2|598561|33|NZ_CP007537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007537 position: 1364620-1364652, mismatch: 0

aagtcattttctgcttctgctaggtttgcttta	CRISPR spacer
aagtcattttctgcttctgctaggtttgcttta	Protospacer
*********************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007537

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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