CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP011114	Paenibacillus durus ATCC 35681 chromosome, complete genome	12 crisprs	WYL,cas14j,RT,DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,c2c10_CAS-V-U3,csa3,cas14k,casR,c2c9_V-U4,DinG,TnpB_regular.1	0	12	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011114_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_1

598468-598837

Unclear

I-C

Consensus_repeat	Method
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	PILER-CR
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	CRT

5 spacers

The CRISPR arrays of NZ_CP011114_1

>merge|NZ_CP011114|1|598468-598837|PILER-CR,CRISPRCasFinder,CRT
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAATTTTTGGAGTGGTATTCGTACAAAATATTTGCCGTACGTCGCTCCCCGTGCGGGAGCGTGGATTGAAATATGTAAAGATCCGACATTATTTAGCCTCCTTTGCTGTCGCTCCCCGTGCGGGAGCGTGGATTGAAATTTGGATCAGTATAGCCGGACCGCCGGAGCGATTGGTAGTCGCTCCCCGTGCGGGAGCGTGGATTGAAATAACGATGTAATCATCTAAGTGTTCGGGGGCATCAATGTCGCTCCCCGTGCGGGAGCGTAGATTGAAAATTCGCTTGGCAGCTTACGGGTGGATACCGAATGTGGTCGCCTCGCCTGGTGGAGTATGAATTGAAA

>NZ_CP011114|1|1|598468-598770|PILER-CR
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	TTTTTGGAGTGGTATTCGTACAAAATATTTGCCGTAC
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	TATGTAAAGATCCGACATTATTTAGCCTCCTTTGCT
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	TTTGGATCAGTATAGCCGGACCGCCGGAGCGATTGGTA
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	TAACGATGTAATCATCTAAGTGTTCGGGGGCATCAAT
GTCGCTCCCCGTGCGGGAGCGTAGATTGAAA

>NZ_CP011114|1|1|598468-598772|CRISPRCasFinder
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	TTTTGGAGTGGTATTCGTACAAAATATTTGCCGTAC
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	ATGTAAAGATCCGACATTATTTAGCCTCCTTTGCT
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	TTGGATCAGTATAGCCGGACCGCCGGAGCGATTGGTA
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	AACGATGTAATCATCTAAGTGTTCGGGGGCATCAAT
GTCGCTCCCCGTGCGGGAGCGTAGATTGAAAAT

>NZ_CP011114|1|1|598468-598837|CRT
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	TTTTTGGAGTGGTATTCGTACAAAATATTTGCCGTAC
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	TATGTAAAGATCCGACATTATTTAGCCTCCTTTGCT
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	TTTGGATCAGTATAGCCGGACCGCCGGAGCGATTGGTA
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAA	TAACGATGTAATCATCTAAGTGTTCGGGGGCATCAAT
GTCGCTCCCCGTGCGGGAGCGTAGATTGAAA	ATTCGCTTGGCAGCTTACGGGTGGATACCGAATGTG
GTCGCCTCGCCTGGTGGAGTATGAATTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025694356.1\|592521_592854_+\|chaperone-CsaA	unknown	unknown	gnl\|CDD\|182232
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380358
NZ_CP011114.1\|WP_036638762.1\|599337_599511_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694354.1\|594072_594381_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|183582
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|225390
NZ_CP011114.1\|WP_046722763.1\|585787_587104_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP011114.1\|WP_025694358.1\|587564_591026_-\|cadherin-like-beta-sandwich-domain-containing-protein	unknown	unknown	gnl\|CDD\|377038
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|366864
NZ_CP011114.1\|WP_025694349.1\|598918_599197_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694357.1\|591470_592352_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|223963
NZ_CP011114.1\|WP_025694355.1\|592965_593739_+\|sporulation-protein	unknown	unknown	gnl\|CDD\|369195
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl\|CDD\|376799
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	unknown	unknown	gnl\|CDD\|289015
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|308978
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025694356.1\|592521_592854_+\|chaperone-CsaA	gnl\|CDD\|182232	PRK10089, PRK10089, chaperone CsaA.	1.25664e-62
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	1.54473e-09
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	gnl\|CDD\|289015	pfam12207, DUF3600, Domain of unknown function (DUF3600). This family of proteins is found in bacteria. Proteins in this family are approximately 230 amino acids in length. This domain is the C terminal of the putative ecf-type sigma factor negative effector.	4.8938e-08
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|183582	PRK12543, PRK12543, RNA polymerase sigma factor; Provisional.	2.07712e-64
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	1.90047e-25
NZ_CP011114.1\|WP_046722763.1\|585787_587104_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.37909e-46
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.01583e-17
NZ_CP011114.1\|WP_025694358.1\|587564_591026_-\|cadherin-like-beta-sandwich-domain-containing-protein	gnl\|CDD\|377038	pfam03442, CBM_X2, Carbohydrate binding domain X2. This domain binds to cellulose and to bacterial cell walls. It is found in glycosyl hydrolases and in scaffolding proteins of cellulosomes (multiprotein glycosyl hydrolase complexes). In the cellulosome it may aid cellulose degradation by anchoring the cellulosome to the bacterial cell wall and by binding it to its substrate. This domain has an Ig-like fold.	2.24899e-16
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	gnl\|CDD\|366864	pfam01934, DUF86, Protein of unknown function DUF86. The function of members of this family is unknown.	0.00129737
NZ_CP011114.1\|WP_025694357.1\|591470_592352_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.09119e-27
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	1.50575e-33
NZ_CP011114.1\|WP_025694355.1\|592965_593739_+\|sporulation-protein	gnl\|CDD\|369195	pfam07070, Spo0M, SpoOM protein. This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH.	3.36751e-104
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	gnl\|CDD\|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	2.66566e-62
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	4.92745e-41
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	gnl\|CDD\|308978	pfam03682, UPF0158, Uncharacterized protein family (UPF0158).	2.63302e-07
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.71168e-06

>NZ_CP011114.1|WP_025694350.1|597757_598099_-|cupin-domain-containing-protein
MEKKELVQFQEYQTDRFTKRIVFKEDKHTVFVLNFGPGQQLPVHKHPGASVYILFLEGSGIVTSDGREISVSQGDVVQISGDEDFSYRSGEGSNSSLYVTLINTPGEQYAQNI
>NZ_CP011114.1|WP_025694351.1|596804_597548_+|DUF3600-domain-containing-protein
MKLEQELREALREESRAWTAPLELKDRILNHKSLNPEGRRMKKWIAAGILAAVLLVPTGAYAGYHYLADSVYGSQERIEPFGGTQQYDYLEEKLQAAKQSFEPQEFAKLMGMLKKLGDYNLKIADDTGVLHPERLSPADQETYKKLNAELEPYFEKLNERVTAKEAVRQVDNVWKDVLARGEQNLSSQDFAKVKGVISGIQKLQAQAARPDGTDRAFTKEEKEQLKELVRQLEPYQDQLGIMLKPVK
>NZ_CP011114.1|WP_025694352.1|596233_596815_+|sigma-70-family-RNA-polymerase-sigma-factor
MNHPKQDSELAALVLAGSREAYSELYEKTITEVYRTVRFLIGESSDTDDVVQEIYIQAYRSLGQYDAARPFRPWLMGVVMRQIRSYRRKSWNHIRLIKKAQQSIALAYDFSGEVVDKISNRPLIASVERLPFKLKQVVILHYLNEYSQEEIADALDIPLGTVKSRIHAALKKLRSKRSSEILLRGKVEDLHEA
>NZ_CP011114.1|WP_025694353.1|594593_595871_+|B12-binding-domain-containing-radical-SAM-protein
MRKKILLIQPENEKINRFRRKQFNNFVQITMPYLAGFIDESKYQITLIDEYRQKIPFRRTFDLVAITVNTPNAYHCYQIAEKFRAQGAKVVMGGPHVTLLPEEASGHCDSILIGEAEETWPEFLDDFHKGKERAVYRSEGIPDLKNLPLPRWDLLKRNRLMKGAVFATRGCPYRCAYCNLKQIYHDRFRVRPIPEVIREISLMKSRFFVFWDDNFFADKAHATELMENLKPLGKKWAAQVTLADCNDDELLERAREAGCLYLFVGLESFSPSALRGVNKGINRVDSYREIIGKLHGHKIMIQAGIVFGFDEDTPATFRDTLAACEELGIDGVTVSLLTPLPRTPVYAGMKQEQRLLSGDWSLYNGKTDVVFGPRNMTSEQLFEGYLDFRRRFYSLPSFIRRMRVSRTHLFYNFIINLGYRLALKR
>NZ_CP011114.1|WP_025694354.1|594072_594381_-|hypothetical-protein
MSIQMGVPQQQVLYQADSQSIQNLKSIRSHLHNICRQHTNQYVRIETIDGQVVTGRIVNCERGFLHLAVPRHGGNRAFYNPYDEMILTLVLYELLVITLLYT
>NZ_CP011114.1|WP_025694355.1|592965_593739_+|sporulation-protein
MSMFKKVLASVGIGSAKVDTRLEEARVVAGGTLRGVVSIRGGQVEQQIDKIYIYVKTQYDKEENDRKITHETEIARILITEGFLLQAGEVREIPFEITVPERTPVSYRHTPVWLMTGLDIKMALDPSDHDYLEVLPSDNMQVVFGALDELGFRLREVSNEYAPRLGAGLPFVQEFEYVPTREFRGALDELEVMFFPRGDNLELYIQIDRRARGLGGFLSEAMGTDESFIRVTFTGNDLRRGVHEVSNQLYELISRYS
>NZ_CP011114.1|WP_025694356.1|592521_592854_+|chaperone-CsaA
MATFDDFLKLDIRVGTIIKAEFFAKAKVPAIKLEIDFGQEIGIKTSSAQITKRYTAEDIIGQQIIGVVNFPPRRIAGFNSEVLVLGGIPEKGDVVLLKPDFKLPDGTPIG
>NZ_CP011114.1|WP_025694357.1|591470_592352_-|helix-turn-helix-transcriptional-regulator
MKKQLHETILYPDVSFPYIMYTHTIHGSIPEGRGFNDLHWHEELQITLVTKGKLVIQVNGIDHELETGQAILINEGVLHVTTNLTHNAQYVSFNFPEKLLAFYADSAMEKNYVLPYTNSSLVSLVIKGDVEWESQVLEMLWDMKKKFDMKKNWGWEYEVSIKTVQLWFTLISNISLSSEEAPKYLKLQQERLQLMLSFIHQNYSNNITLQEIADVAHLSVSECTRSFKRTIHMTPYDYLIKYRIKKSSELLISTDYTITEIAHRVGFNHVNHFIQSFKKYHERTPKDFRKFRK
>NZ_CP011114.1|WP_025694358.1|587564_591026_-|cadherin-like-beta-sandwich-domain-containing-protein
MRLARYFFISFTVLILITALPWYVRAQISDADADLVSIYQGTGSLSPAFSPSVTEYWVRMHSSAIGYYTAAIPANSGAAMEYSMNGGFWTAIPSYTSTGYLPTNRGDNTFQIKVTSADLTATKTYTIHVYYPSTNDADLIDLHSDEAALSPGFQSSVMNYTAHVPYTTSSITFTGVLDDPAASLTINGTAATNGAASGAIPLNVGSNTIVIATASYDQTANKTYTITVTRAAPSTNTGLSDLTVPGNLLSPAFATGTTAYTLASAAYAADSLTVIPTAADPASTVKVRVNGGSYMTVNSGSASGSLALNVGSNTIEIQVTAQDGITSNVYTITVKRKNNNAALSELLVSPGSLNEAFSSERLDYSLEDAGSTTDTLTVSPVLADPAGASVRVNVNGGGYTPVTNGHGIDVPLTPGSNLITLEVIAEDSGYFKRYTISVTRLQDSAIYPASGIFDKYSSNPVEGHYQDIVTTLTLNGNTLSSIKLDDTILEASSYTLSANTITIHKEYLAALETGHHVIAFVMNKGSNALYTLFVNDTTPPILNSAVAGDGHVQLAWSPVDGSTGYKIYQSLTSGTYGPEVATVTGSTYDFDATGLTNGTTSYFVVKATNPGGDSAVSNELSATPRTVPAAPTDVNAVAGNGQATVSFTAPSDNGGSPIIGYEVTALPGNIIAEGTSSPITVTGLSNGTAYTFTVKAVNSAGKSAGSAVSNEIIPRPSSNAGDGDGTPTNPVTTGNAGTVMNILVNGKAENWGLATTTRVNNQSVTTISLNPAKFMEFFAAASPGTVITIPFSPGSDVVIGEFNGQMIKTLEQNQAVVKIQTDQASYTLPARQIHIESISHQLEQSALLQDVIVQIEIAAPAADMLQTIENAAFKGNFKLLAPPLNFTVRAAYHSSSLEVSRFNAYVERTIAIPGSVDASQSTTGIVVEPGGLVHPVPTQLTVMDGKYYATIKSLSNSTYAIISHPVEFQDTASHWAKSAVNDLGSRMIINGFDNGRYAPDQDITRAEFAAILVRGLGVKLVHGGTAFPDVKASDWYSDAIQTAYAHQFISGFEDGSFHPTDKVTREQAIVMISKAMTLTGLKTKLPAQETNAALAPFKDAANASNWAKESIADCLQSGIVSGRNKMELAPKAPITRAEVAVIIQRFLQKSELI
>NZ_CP011114.1|WP_046722763.1|585787_587104_+|MFS-transporter
MEAPLTKRETRADRGLFGNKIYMRVYAAYAAAEFGDWFDMLAIQVLVGYRWQAGPLMLALIPVSLALPGIVLGSAAGVAADRLNKLKLMRLCNLLTAVLTAAVLLAPGMLWLLPLLALRSAVSALNVPAQQSLTRSIVREDQLLQAASLNGFVTQGSKIAGPLLGGLALAALSPAWCIALNACMRLLSYVLLLSIKNADTSGSTGADSDVRKKAGDQAADGDSLSARTMWKEGWSFIFRSRLLRNTMLFGLMGALSIQMVDFQFASLFRTLAPDREYLLGWLVSAAGAGAVLTIAAMNKVGRGAGYGLRLGGGYALIGAAIGGLGLLPPGVSLLPVLLLGLLMGAGNGMFMITFNYCLQKETPPHMTGRVFGIQSMVLNAAMIAAPLLGGTMVDLAGPRRIFASFGLVIAMIGAAGILLRRLLWPEGKEGREGGHKFQ
>NZ_CP011114.1|WP_025694349.1|598918_599197_-|hypothetical-protein
MAYMEQAFNQFLSARMEYIANSILSNCNEYRQLIEECNQLFLTLMTDLPQEYKEMLQNYDTSTALLQGIAETLMYKQGLKDGISLNRFLTDR
>NZ_CP011114.1|WP_036638762.1|599337_599511_+|hypothetical-protein
MATDKRVFTLRLKEENFDKIKYIADKNKRSIAMQIEYLIEQHIEHFEKEKGIIKTDE
>NZ_CP011114.1|WP_025694813.1|601476_601713_-|helix-turn-helix-transcriptional-regulator
MEYNRYTLHCKLDEILKEHDNMSVLKLSKEIGHRRTTIMELMHNTNMEKKKISAALIVKLCLYFDISPNELFEVRPKE
>NZ_CP011114.1|WP_025694814.1|604519_604990_+|ribose-5-phosphate-isomerase-B
MKIAVAGDHAGFSLKEEVKALLTSQGHEVVDFGTHSEEASDLPDYIYPAALAVAEGKADRGIFIDGVGYGSAMIANKIYGVYAAVCQDPFCAELARSHSDTNVLCIGGKIIGSAIALEIVKVWMTTDHLGDVEKYKRRVDKVVEISEKHLKKLSEL
>NZ_CP011114.1|WP_025694815.1|605107_605320_-|DUF86-domain-containing-protein
MNRDILLNKTENIRICIIFNLQRCCEACIELAMHSVSELKLGVSQSSRDAFEMLYNKGIIDEKLKEYMSR
>NZ_CP011114.1|WP_025694817.1|606115_606577_+|hypothetical-protein
MDKLTLTEAQLREIVDSYDMQHEGIDSFFNLESKEVVFVNNEFSDPEDEELEEEIEEGFGEIWFRLPERYSSDGYRDMEDFVDIVSDERLRELLITSLRGGRGFFRRFKDTLGDNPEELERYYQFVYERNRERVLKWMEAEFDLEIEIIGGED
>NZ_CP011114.1|WP_025694818.1|606927_608016_+|outer-membrane-lipoprotein-carrier-protein-LolA
MRRIAWVLAIIMSVTLIMTGCGKKDSASVVKDLNDVADKLESKTGAYQGEGTMTLYTGEQPQEYRVEVWYKNPSYYRISLANVQKNITQIVLRNDEGVFVLTPSLGKSFRFQSDWPDKQGQVYLYQTLVKGIVADNNRQFVADKDSYVFEVAANYQSSALVRQKIWLDKKTYAPKQVQVSDSEAKVVVDVKFNKFAFNPEFSADSFDMQKNMASGGNSKNTVAQVDENGNPLPAADNQEGTQAQANAALGDFGIIEPGYTPEGVTFKDSNKVENSDNHAVLLRYDGIYQYTIMESRPLDQAVSLAPGTLIDLGFTAGLLTGDEQQTLTWMSGDGVEFRITSANLPPSEMMEIAASMQDQTGK
>NZ_CP011114.1|WP_025694819.1|608241_609444_+|alanine-racemase
MQESYRPTVAEIDLDALRANYESFRRHLPAGVKFMACVKGNAYGHGAVEVTRELERLGADYVSVAFLDEAIELRQAGIVLPILVLGYTPPEAIAAAWENDVTVTLFTPEGLEAASKLPLNDSRKLKVHIKIDSGMGRLGLLPDDVPLFIEEAQRVRQIELEGMFTHFAKADEADKSYTLEQYRRFMGVTEALRERQIHIPIIHTGNSATAIDTPHLSPNMVRVGVSIYGFYPSTEVNRQQVKLHPVMTLKTKAVYVKSLPESWGVSYGTRYRADNGEYIATLPIGYADGYSRMLSGKAEVLIRGRRVPVVGTICMDQCMVSLKSFANEAEQIKAGEEVVLIGRQAGVSITADELALLLGTIHYEVTCMLAHRVPRVYIREGSAPRLVNALLQAPSPNPVS
>NZ_CP011114.1|WP_175491834.1|609668_609920_+|ribbon-helix-helix-protein,-CopG-family
MISLPDHLLQEVDGIVQMENSNRSELIRQAMKLYLSERRKRSIRESMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLVSGV
>NZ_CP011114.1|WP_025691534.1|609923_610274_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDASSHGFDRDSVILLEQVRTIDKQRLTDKITHLDDETMKKVDDSLQISLGLIDF

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Crispr_ID: NZ_CP011114_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_2

600041-601412

Unclear

I-C

Consensus_repeat	Method
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	PILER-CR
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CRT

20 spacers

The CRISPR arrays of NZ_CP011114_2

>merge|NZ_CP011114|2|600041-601412|PILER-CR,CRISPRCasFinder,CRT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAATCTCCCACAGAACCGGAGCCGGAGCGTAAAGGGAGTCGCTCTCCATGCGAGAGCGTGGATTGAAATCTTGGGCGTCGTCGATGCTTCGCCACTCTCGTACCGGTCGCTCTCCATGCGAGAGCGTGGATTGAAATTTCACGGTTGAAGGCGATACTTCAAACTGTCTTGCCGTCGCTCTCCATGCGAGAGCGTGGATTGAAATGGGTTAGCGGTTGGCGGATCGGAGTTTACGGATGGTCGCTCTCCATGCGAGAGCGTGGATTGAAATATCTTTGCCAAGTTATTTATCAGATCGCGAACAGCGTCGCTCTCCATGCGAGAGCGTGGATTGAAATTTGGAGCCAGTACACACCAGCCTCTGCTGCTCCTTGTCGCTCTCCATGCGAGAGCGTGGATTGAAATAACTGCACCGTTCCCGGCGATCCCGCCACAGCCACGTCGCTCTCCATGCGAGAGCGTGGATTGAAATCGTTAATACTCCGCCCGTATCACGCAAGTTGTACGTCGCTCTCCATGCGAGAGCGTGGATTGAAATACTGGTGAAGCCCTACGGTCTTGGTCTTTATAAGTCGCTCTCCATGCGAGAGCGTGGATTGAAATCATGTTACTTCTGTGCTTTGCTCTGACTCATCCCACGGTCGCTCTCCATGCGAGAGCGTGGATTGAAATTGTCCAAGTGGATGCTTGTCGATCCTCGGCCTTGTCGTCGCTCTCCATGCGAGAGCGTGGATTGAAATGAGACAACGAGAACGCTGATAAGCCATACTCAGAGTCGCTCTCCATGCGAGAGCGTGGATTGAAATCATCTAAACCAAGAAGAAACATTATCGTGGCAACGTCGCTCTCCATGCGAGAGCGTGGATTGAAATAACCGAATGAACCAGCCAACGAGAAGTCCTATGGTCGCTCTCCATGCGAGAGCGTGGATTGAAATTACACGAATTGGTTTCCCGTTTACATATTCCGTCGTCGTCGCTCTCCATGCGAGAGCGTGGATTGAAATCTGAGCATGCAGCTATGGTAATTGGGAGCCCCGGTCGCTCTCCATGCGAGAGCGTGGATTGAAATCCGTTGACTGATCTCATGGTCATTTTGGGGCTTGTCGTCGCTCTCCATGCGAGAGCGTGTATTGAAATAGATCAACCTGGACAAGCTGGACATCCCCTCCTACAAGTCGCTCTCCATGCGAGAGCGTGGATTGAAATAATTGAATCTCTCGAAATATTTTTGATAAAAAAACGTCGCTCTCCATGCGAGAGCGTGGATTGAAATCGCTATGAAATGGTTTATTGTGGGCGGGGCGTTATTGTCGCTCTCCATGCGAGAGTGTGGATGAAATTG

>NZ_CP011114|2|2|600041-601343|PILER-CR
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTCCCACAGAACCGGAGCCGGAGCGTAAAGGGA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTTGGGCGTCGTCGATGCTTCGCCACTCTCGTACCG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTCACGGTTGAAGGCGATACTTCAAACTGTCTTGCC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	GGGTTAGCGGTTGGCGGATCGGAGTTTACGGATG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ATCTTTGCCAAGTTATTTATCAGATCGCGAACAGC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTGGAGCCAGTACACACCAGCCTCTGCTGCTCCTT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AACTGCACCGTTCCCGGCGATCCCGCCACAGCCAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CGTTAATACTCCGCCCGTATCACGCAAGTTGTAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ACTGGTGAAGCCCTACGGTCTTGGTCTTTATAA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CATGTTACTTCTGTGCTTTGCTCTGACTCATCCCACG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TGTCCAAGTGGATGCTTGTCGATCCTCGGCCTTGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	GAGACAACGAGAACGCTGATAAGCCATACTCAGA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CATCTAAACCAAGAAGAAACATTATCGTGGCAAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AACCGAATGAACCAGCCAACGAGAAGTCCTATG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TACACGAATTGGTTTCCCGTTTACATATTCCGTCGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTGAGCATGCAGCTATGGTAATTGGGAGCCCCG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CCGTTGACTGATCTCATGGTCATTTTGGGGCTTGTC
GTCGCTCTCCATGCGAGAGCGTGTATTGAAAT	AGATCAACCTGGACAAGCTGGACATCCCCTCCTACAA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AATTGAATCTCTCGAAATATTTTTGATAAAAAAAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT

>NZ_CP011114|2|2|600041-601412|CRISPRCasFinder
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTCCCACAGAACCGGAGCCGGAGCGTAAAGGGA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTTGGGCGTCGTCGATGCTTCGCCACTCTCGTACCG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTCACGGTTGAAGGCGATACTTCAAACTGTCTTGCC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	GGGTTAGCGGTTGGCGGATCGGAGTTTACGGATG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ATCTTTGCCAAGTTATTTATCAGATCGCGAACAGC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTGGAGCCAGTACACACCAGCCTCTGCTGCTCCTT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AACTGCACCGTTCCCGGCGATCCCGCCACAGCCAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CGTTAATACTCCGCCCGTATCACGCAAGTTGTAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ACTGGTGAAGCCCTACGGTCTTGGTCTTTATAA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CATGTTACTTCTGTGCTTTGCTCTGACTCATCCCACG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TGTCCAAGTGGATGCTTGTCGATCCTCGGCCTTGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	GAGACAACGAGAACGCTGATAAGCCATACTCAGA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CATCTAAACCAAGAAGAAACATTATCGTGGCAAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AACCGAATGAACCAGCCAACGAGAAGTCCTATG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TACACGAATTGGTTTCCCGTTTACATATTCCGTCGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTGAGCATGCAGCTATGGTAATTGGGAGCCCCG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CCGTTGACTGATCTCATGGTCATTTTGGGGCTTGTC
GTCGCTCTCCATGCGAGAGCGTGTATTGAAAT	AGATCAACCTGGACAAGCTGGACATCCCCTCCTACAA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AATTGAATCTCTCGAAATATTTTTGATAAAAAAAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CGCTATGAAATGGTTTATTGTGGGCGGGGCGTTATT
GTCGCTCTCCATGCGAGAGTGTGGATGAAATTG

>NZ_CP011114|2|2|600041-601411|CRT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTCCCACAGAACCGGAGCCGGAGCGTAAAGGGA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTTGGGCGTCGTCGATGCTTCGCCACTCTCGTACCG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTCACGGTTGAAGGCGATACTTCAAACTGTCTTGCC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	GGGTTAGCGGTTGGCGGATCGGAGTTTACGGATG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ATCTTTGCCAAGTTATTTATCAGATCGCGAACAGC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTGGAGCCAGTACACACCAGCCTCTGCTGCTCCTT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AACTGCACCGTTCCCGGCGATCCCGCCACAGCCAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CGTTAATACTCCGCCCGTATCACGCAAGTTGTAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ACTGGTGAAGCCCTACGGTCTTGGTCTTTATAA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CATGTTACTTCTGTGCTTTGCTCTGACTCATCCCACG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TGTCCAAGTGGATGCTTGTCGATCCTCGGCCTTGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	GAGACAACGAGAACGCTGATAAGCCATACTCAGA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CATCTAAACCAAGAAGAAACATTATCGTGGCAAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AACCGAATGAACCAGCCAACGAGAAGTCCTATG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TACACGAATTGGTTTCCCGTTTACATATTCCGTCGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CTGAGCATGCAGCTATGGTAATTGGGAGCCCCG
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CCGTTGACTGATCTCATGGTCATTTTGGGGCTTGTC
GTCGCTCTCCATGCGAGAGCGTGTATTGAAAT	AGATCAACCTGGACAAGCTGGACATCCCCTCCTACAA
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	AATTGAATCTCTCGAAATATTTTTGATAAAAAAAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CGCTATGAAATGGTTTATTGTGGGCGGGGCGTTATT
GTCGCTCTCCATGCGAGAGTGTGGATGAAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025694356.1\|592521_592854_+\|chaperone-CsaA	unknown	unknown	gnl\|CDD\|182232
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380358
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	unknown	unknown	gnl\|CDD\|289015
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|183582
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|225390
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP011114.1\|WP_036638762.1\|599337_599511_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|366864
NZ_CP011114.1\|WP_025694349.1\|598918_599197_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694357.1\|591470_592352_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|223963
NZ_CP011114.1\|WP_025694355.1\|592965_593739_+\|sporulation-protein	unknown	unknown	gnl\|CDD\|369195
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl\|CDD\|376799
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP011114.1\|WP_025694354.1\|594072_594381_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|308978
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025694356.1\|592521_592854_+\|chaperone-CsaA	gnl\|CDD\|182232	PRK10089, PRK10089, chaperone CsaA.	1.25664e-62
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	1.54473e-09
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	1.19044e-05
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	gnl\|CDD\|289015	pfam12207, DUF3600, Domain of unknown function (DUF3600). This family of proteins is found in bacteria. Proteins in this family are approximately 230 amino acids in length. This domain is the C terminal of the putative ecf-type sigma factor negative effector.	4.8938e-08
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|183582	PRK12543, PRK12543, RNA polymerase sigma factor; Provisional.	2.07712e-64
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	1.90047e-25
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.01583e-17
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	4.92745e-41
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	gnl\|CDD\|366864	pfam01934, DUF86, Protein of unknown function DUF86. The function of members of this family is unknown.	0.00129737
NZ_CP011114.1\|WP_025694357.1\|591470_592352_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.09119e-27
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	1.50575e-33
NZ_CP011114.1\|WP_025694355.1\|592965_593739_+\|sporulation-protein	gnl\|CDD\|369195	pfam07070, Spo0M, SpoOM protein. This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH.	3.36751e-104
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	gnl\|CDD\|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	2.66566e-62
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	gnl\|CDD\|308978	pfam03682, UPF0158, Uncharacterized protein family (UPF0158).	2.63302e-07
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.71168e-06

>NZ_CP011114.1|WP_036638762.1|599337_599511_+|hypothetical-protein
MATDKRVFTLRLKEENFDKIKYIADKNKRSIAMQIEYLIEQHIEHFEKEKGIIKTDE
>NZ_CP011114.1|WP_025694349.1|598918_599197_-|hypothetical-protein
MAYMEQAFNQFLSARMEYIANSILSNCNEYRQLIEECNQLFLTLMTDLPQEYKEMLQNYDTSTALLQGIAETLMYKQGLKDGISLNRFLTDR
>NZ_CP011114.1|WP_025694350.1|597757_598099_-|cupin-domain-containing-protein
MEKKELVQFQEYQTDRFTKRIVFKEDKHTVFVLNFGPGQQLPVHKHPGASVYILFLEGSGIVTSDGREISVSQGDVVQISGDEDFSYRSGEGSNSSLYVTLINTPGEQYAQNI
>NZ_CP011114.1|WP_025694351.1|596804_597548_+|DUF3600-domain-containing-protein
MKLEQELREALREESRAWTAPLELKDRILNHKSLNPEGRRMKKWIAAGILAAVLLVPTGAYAGYHYLADSVYGSQERIEPFGGTQQYDYLEEKLQAAKQSFEPQEFAKLMGMLKKLGDYNLKIADDTGVLHPERLSPADQETYKKLNAELEPYFEKLNERVTAKEAVRQVDNVWKDVLARGEQNLSSQDFAKVKGVISGIQKLQAQAARPDGTDRAFTKEEKEQLKELVRQLEPYQDQLGIMLKPVK
>NZ_CP011114.1|WP_025694352.1|596233_596815_+|sigma-70-family-RNA-polymerase-sigma-factor
MNHPKQDSELAALVLAGSREAYSELYEKTITEVYRTVRFLIGESSDTDDVVQEIYIQAYRSLGQYDAARPFRPWLMGVVMRQIRSYRRKSWNHIRLIKKAQQSIALAYDFSGEVVDKISNRPLIASVERLPFKLKQVVILHYLNEYSQEEIADALDIPLGTVKSRIHAALKKLRSKRSSEILLRGKVEDLHEA
>NZ_CP011114.1|WP_025694353.1|594593_595871_+|B12-binding-domain-containing-radical-SAM-protein
MRKKILLIQPENEKINRFRRKQFNNFVQITMPYLAGFIDESKYQITLIDEYRQKIPFRRTFDLVAITVNTPNAYHCYQIAEKFRAQGAKVVMGGPHVTLLPEEASGHCDSILIGEAEETWPEFLDDFHKGKERAVYRSEGIPDLKNLPLPRWDLLKRNRLMKGAVFATRGCPYRCAYCNLKQIYHDRFRVRPIPEVIREISLMKSRFFVFWDDNFFADKAHATELMENLKPLGKKWAAQVTLADCNDDELLERAREAGCLYLFVGLESFSPSALRGVNKGINRVDSYREIIGKLHGHKIMIQAGIVFGFDEDTPATFRDTLAACEELGIDGVTVSLLTPLPRTPVYAGMKQEQRLLSGDWSLYNGKTDVVFGPRNMTSEQLFEGYLDFRRRFYSLPSFIRRMRVSRTHLFYNFIINLGYRLALKR
>NZ_CP011114.1|WP_025694354.1|594072_594381_-|hypothetical-protein
MSIQMGVPQQQVLYQADSQSIQNLKSIRSHLHNICRQHTNQYVRIETIDGQVVTGRIVNCERGFLHLAVPRHGGNRAFYNPYDEMILTLVLYELLVITLLYT
>NZ_CP011114.1|WP_025694355.1|592965_593739_+|sporulation-protein
MSMFKKVLASVGIGSAKVDTRLEEARVVAGGTLRGVVSIRGGQVEQQIDKIYIYVKTQYDKEENDRKITHETEIARILITEGFLLQAGEVREIPFEITVPERTPVSYRHTPVWLMTGLDIKMALDPSDHDYLEVLPSDNMQVVFGALDELGFRLREVSNEYAPRLGAGLPFVQEFEYVPTREFRGALDELEVMFFPRGDNLELYIQIDRRARGLGGFLSEAMGTDESFIRVTFTGNDLRRGVHEVSNQLYELISRYS
>NZ_CP011114.1|WP_025694356.1|592521_592854_+|chaperone-CsaA
MATFDDFLKLDIRVGTIIKAEFFAKAKVPAIKLEIDFGQEIGIKTSSAQITKRYTAEDIIGQQIIGVVNFPPRRIAGFNSEVLVLGGIPEKGDVVLLKPDFKLPDGTPIG
>NZ_CP011114.1|WP_025694357.1|591470_592352_-|helix-turn-helix-transcriptional-regulator
MKKQLHETILYPDVSFPYIMYTHTIHGSIPEGRGFNDLHWHEELQITLVTKGKLVIQVNGIDHELETGQAILINEGVLHVTTNLTHNAQYVSFNFPEKLLAFYADSAMEKNYVLPYTNSSLVSLVIKGDVEWESQVLEMLWDMKKKFDMKKNWGWEYEVSIKTVQLWFTLISNISLSSEEAPKYLKLQQERLQLMLSFIHQNYSNNITLQEIADVAHLSVSECTRSFKRTIHMTPYDYLIKYRIKKSSELLISTDYTITEIAHRVGFNHVNHFIQSFKKYHERTPKDFRKFRK
>NZ_CP011114.1|WP_025694813.1|601476_601713_-|helix-turn-helix-transcriptional-regulator
MEYNRYTLHCKLDEILKEHDNMSVLKLSKEIGHRRTTIMELMHNTNMEKKKISAALIVKLCLYFDISPNELFEVRPKE
>NZ_CP011114.1|WP_025694814.1|604519_604990_+|ribose-5-phosphate-isomerase-B
MKIAVAGDHAGFSLKEEVKALLTSQGHEVVDFGTHSEEASDLPDYIYPAALAVAEGKADRGIFIDGVGYGSAMIANKIYGVYAAVCQDPFCAELARSHSDTNVLCIGGKIIGSAIALEIVKVWMTTDHLGDVEKYKRRVDKVVEISEKHLKKLSEL
>NZ_CP011114.1|WP_025694815.1|605107_605320_-|DUF86-domain-containing-protein
MNRDILLNKTENIRICIIFNLQRCCEACIELAMHSVSELKLGVSQSSRDAFEMLYNKGIIDEKLKEYMSR
>NZ_CP011114.1|WP_025694817.1|606115_606577_+|hypothetical-protein
MDKLTLTEAQLREIVDSYDMQHEGIDSFFNLESKEVVFVNNEFSDPEDEELEEEIEEGFGEIWFRLPERYSSDGYRDMEDFVDIVSDERLRELLITSLRGGRGFFRRFKDTLGDNPEELERYYQFVYERNRERVLKWMEAEFDLEIEIIGGED
>NZ_CP011114.1|WP_025694818.1|606927_608016_+|outer-membrane-lipoprotein-carrier-protein-LolA
MRRIAWVLAIIMSVTLIMTGCGKKDSASVVKDLNDVADKLESKTGAYQGEGTMTLYTGEQPQEYRVEVWYKNPSYYRISLANVQKNITQIVLRNDEGVFVLTPSLGKSFRFQSDWPDKQGQVYLYQTLVKGIVADNNRQFVADKDSYVFEVAANYQSSALVRQKIWLDKKTYAPKQVQVSDSEAKVVVDVKFNKFAFNPEFSADSFDMQKNMASGGNSKNTVAQVDENGNPLPAADNQEGTQAQANAALGDFGIIEPGYTPEGVTFKDSNKVENSDNHAVLLRYDGIYQYTIMESRPLDQAVSLAPGTLIDLGFTAGLLTGDEQQTLTWMSGDGVEFRITSANLPPSEMMEIAASMQDQTGK
>NZ_CP011114.1|WP_025694819.1|608241_609444_+|alanine-racemase
MQESYRPTVAEIDLDALRANYESFRRHLPAGVKFMACVKGNAYGHGAVEVTRELERLGADYVSVAFLDEAIELRQAGIVLPILVLGYTPPEAIAAAWENDVTVTLFTPEGLEAASKLPLNDSRKLKVHIKIDSGMGRLGLLPDDVPLFIEEAQRVRQIELEGMFTHFAKADEADKSYTLEQYRRFMGVTEALRERQIHIPIIHTGNSATAIDTPHLSPNMVRVGVSIYGFYPSTEVNRQQVKLHPVMTLKTKAVYVKSLPESWGVSYGTRYRADNGEYIATLPIGYADGYSRMLSGKAEVLIRGRRVPVVGTICMDQCMVSLKSFANEAEQIKAGEEVVLIGRQAGVSITADELALLLGTIHYEVTCMLAHRVPRVYIREGSAPRLVNALLQAPSPNPVS
>NZ_CP011114.1|WP_175491834.1|609668_609920_+|ribbon-helix-helix-protein,-CopG-family
MISLPDHLLQEVDGIVQMENSNRSELIRQAMKLYLSERRKRSIRESMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLVSGV
>NZ_CP011114.1|WP_025691534.1|609923_610274_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDASSHGFDRDSVILLEQVRTIDKQRLTDKITHLDDETMKKVDDSLQISLGLIDF
>NZ_CP011114.1|WP_025694820.1|610476_612666_+|RNA-binding-transcriptional-accessory-protein
MNIVSDEAARRERQMMIGQIAKELGLSERQVGTTAGLLDEGNTIPFIARYRKEMTGELDENALRDIEERLSYLRSLGERKREVIRIIEEQGKLTDELREQIAGAVKLQEVEDLYRPYRQKRKTRASVAKEKGLGPLADWIMEQRRGGNPEAEAGKYVDPAKGVESAEQALQGAQDIIAEAIADDAAVRSWVRQFTASQGILVSEAKDKEQESVYENYYSYREPVHKMPPHRILAINRGERENVLKVSIEVDAARIHAHITRKLVKGPSPVKELLEAVAEDAYKRLIAPSVEREVRGEMTEKGENQAISIFSGNLRSLLLQPPVKGRRVLGVDPAYRTGCKLAVVDETGKLLEVAVTYPTPPHNKKREAAEKFKELIAKYGIQLIVIGNGTGSRETEQFTAETIAEIGDPGLAYLIVNEAGASVYSASKLAQEEFPDLDVAERSAASIARRVQDPLAELVKIEPKAIGVGQYQHDVSQKHLDESLTAVVESAVNHVGVDVNTASPSLLSYVAGINSTIAKNIVKFREENGSFKNRKQLQKVPRLGAKSYEQCIGFLRIPEGENTLDRTPIHPESYDVVSRLFKELGLALSQIGSKELAAELAAQNPEELAARLDVGVPTLRDILESLQRPGRDPREELPPPIFRTDVLKIEDLAPGMELQGTVRNVIDFGAFVDIGIKNDGLVHISQLSSSFVKHPMDVVSVGDNVTVWVLSVDLKKGRVSLTMRPPRGE
>NZ_CP011114.1|WP_025695199.1|612813_613785_-|S-layer-homology-domain-containing-protein
MMKRQTFRHNAKKMTIACGILAGAVLFGASAFAFSDLKGDPAEAKINALHEAGVINGVTSQLFAPKSKMTYGQAVQLIVSGLALKTNPVPGSPSKASDYFAKVDDKSWYAPSLLIAVQNGLPLDKAVNPNAAVSRATFAQLLDAALKAKGDFPVTEMYFNIADGGKLSAEVNGSLQTLLNMRIISLDPGGKFRPNDAVTRSEAAAWVHDARAFVQSMFGGDGSADTSQGADINVEKAADGVNKVSVTVGNLPNPGYGLTIAKIEFGEGKKAVIYYEVTKPGPGMYPQVISKATAVAYLPEGYVASAKPMPGSYTPPEPDSPQF

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Crispr_ID: NZ_CP011114_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_4

603997-604297

TypeI

I-C

Consensus_repeat	Method
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	PILER-CR
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CRT

4 spacers

cas3

The CRISPR arrays of NZ_CP011114_4

>merge|NZ_CP011114|4|603997-604297|PILER-CR,CRISPRCasFinder,CRT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAATTGAACTGCAATCCCAATAACACAACCATCCAAGAGTCGTCGCTCTCCATGCGAGAGCGTGGATTGAAATATCGGCTGTGACGGCATTCGCTTGGATATGATTACGTCGCTCTCCATGCGAGAGCGTGGATTGAAATTTCGAGACCAATAACGTCATATTCTTGTCCTTGATGTCGCTCTCCATGCGAGAGCGTGGATTGAAATTTTTTGGCTGGCCAGAAGGCAACCTCTGACGCGTGTCGCTCTCCATGCGAGAGCGTGGATTGAAAT

>NZ_CP011114|4|3|603997-604297|PILER-CR
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TGAACTGCAATCCCAATAACACAACCATCCAAGAGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ATCGGCTGTGACGGCATTCGCTTGGATATGATTAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTCGAGACCAATAACGTCATATTCTTGTCCTTGAT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTTTTGGCTGGCCAGAAGGCAACCTCTGACGCGT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT

>NZ_CP011114|4|4|603997-604297|CRISPRCasFinder
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TGAACTGCAATCCCAATAACACAACCATCCAAGAGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ATCGGCTGTGACGGCATTCGCTTGGATATGATTAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTCGAGACCAATAACGTCATATTCTTGTCCTTGAT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTTTTGGCTGGCCAGAAGGCAACCTCTGACGCGT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT

>NZ_CP011114|4|4|603997-604297|CRT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TGAACTGCAATCCCAATAACACAACCATCCAAGAGTC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	ATCGGCTGTGACGGCATTCGCTTGGATATGATTAC
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTCGAGACCAATAACGTCATATTCTTGTCCTTGAT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	TTTTTGGCTGGCCAGAAGGCAACCTCTGACGCGT
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025694356.1\|592521_592854_+\|chaperone-CsaA	unknown	unknown	gnl\|CDD\|182232
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380358
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	unknown	unknown	gnl\|CDD\|289015
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|225390
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP011114.1\|WP_036638762.1\|599337_599511_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|366864
NZ_CP011114.1\|WP_025694349.1\|598918_599197_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|223963
NZ_CP011114.1\|WP_025694355.1\|592965_593739_+\|sporulation-protein	unknown	unknown	gnl\|CDD\|369195
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl\|CDD\|376799
NZ_CP011114.1\|WP_025694354.1\|594072_594381_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|308978
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|183582

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025694356.1\|592521_592854_+\|chaperone-CsaA	gnl\|CDD\|182232	PRK10089, PRK10089, chaperone CsaA.	1.25664e-62
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	1.54473e-09
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	gnl\|CDD\|289015	pfam12207, DUF3600, Domain of unknown function (DUF3600). This family of proteins is found in bacteria. Proteins in this family are approximately 230 amino acids in length. This domain is the C terminal of the putative ecf-type sigma factor negative effector.	4.8938e-08
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.71168e-06
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	1.90047e-25
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	4.92745e-41
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.01583e-17
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	1.19044e-05
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	gnl\|CDD\|366864	pfam01934, DUF86, Protein of unknown function DUF86. The function of members of this family is unknown.	0.00129737
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	1.50575e-33
NZ_CP011114.1\|WP_025694355.1\|592965_593739_+\|sporulation-protein	gnl\|CDD\|369195	pfam07070, Spo0M, SpoOM protein. This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH.	3.36751e-104
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	gnl\|CDD\|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	2.66566e-62
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	gnl\|CDD\|308978	pfam03682, UPF0158, Uncharacterized protein family (UPF0158).	2.63302e-07
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.76854e-66
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|183582	PRK12543, PRK12543, RNA polymerase sigma factor; Provisional.	2.07712e-64

>NZ_CP011114.1|WP_025694813.1|601476_601713_-|helix-turn-helix-transcriptional-regulator
MEYNRYTLHCKLDEILKEHDNMSVLKLSKEIGHRRTTIMELMHNTNMEKKKISAALIVKLCLYFDISPNELFEVRPKE
>NZ_CP011114.1|WP_036638762.1|599337_599511_+|hypothetical-protein
MATDKRVFTLRLKEENFDKIKYIADKNKRSIAMQIEYLIEQHIEHFEKEKGIIKTDE
>NZ_CP011114.1|WP_025694349.1|598918_599197_-|hypothetical-protein
MAYMEQAFNQFLSARMEYIANSILSNCNEYRQLIEECNQLFLTLMTDLPQEYKEMLQNYDTSTALLQGIAETLMYKQGLKDGISLNRFLTDR
>NZ_CP011114.1|WP_025694350.1|597757_598099_-|cupin-domain-containing-protein
MEKKELVQFQEYQTDRFTKRIVFKEDKHTVFVLNFGPGQQLPVHKHPGASVYILFLEGSGIVTSDGREISVSQGDVVQISGDEDFSYRSGEGSNSSLYVTLINTPGEQYAQNI
>NZ_CP011114.1|WP_025694351.1|596804_597548_+|DUF3600-domain-containing-protein
MKLEQELREALREESRAWTAPLELKDRILNHKSLNPEGRRMKKWIAAGILAAVLLVPTGAYAGYHYLADSVYGSQERIEPFGGTQQYDYLEEKLQAAKQSFEPQEFAKLMGMLKKLGDYNLKIADDTGVLHPERLSPADQETYKKLNAELEPYFEKLNERVTAKEAVRQVDNVWKDVLARGEQNLSSQDFAKVKGVISGIQKLQAQAARPDGTDRAFTKEEKEQLKELVRQLEPYQDQLGIMLKPVK
>NZ_CP011114.1|WP_025694352.1|596233_596815_+|sigma-70-family-RNA-polymerase-sigma-factor
MNHPKQDSELAALVLAGSREAYSELYEKTITEVYRTVRFLIGESSDTDDVVQEIYIQAYRSLGQYDAARPFRPWLMGVVMRQIRSYRRKSWNHIRLIKKAQQSIALAYDFSGEVVDKISNRPLIASVERLPFKLKQVVILHYLNEYSQEEIADALDIPLGTVKSRIHAALKKLRSKRSSEILLRGKVEDLHEA
>NZ_CP011114.1|WP_025694353.1|594593_595871_+|B12-binding-domain-containing-radical-SAM-protein
MRKKILLIQPENEKINRFRRKQFNNFVQITMPYLAGFIDESKYQITLIDEYRQKIPFRRTFDLVAITVNTPNAYHCYQIAEKFRAQGAKVVMGGPHVTLLPEEASGHCDSILIGEAEETWPEFLDDFHKGKERAVYRSEGIPDLKNLPLPRWDLLKRNRLMKGAVFATRGCPYRCAYCNLKQIYHDRFRVRPIPEVIREISLMKSRFFVFWDDNFFADKAHATELMENLKPLGKKWAAQVTLADCNDDELLERAREAGCLYLFVGLESFSPSALRGVNKGINRVDSYREIIGKLHGHKIMIQAGIVFGFDEDTPATFRDTLAACEELGIDGVTVSLLTPLPRTPVYAGMKQEQRLLSGDWSLYNGKTDVVFGPRNMTSEQLFEGYLDFRRRFYSLPSFIRRMRVSRTHLFYNFIINLGYRLALKR
>NZ_CP011114.1|WP_025694354.1|594072_594381_-|hypothetical-protein
MSIQMGVPQQQVLYQADSQSIQNLKSIRSHLHNICRQHTNQYVRIETIDGQVVTGRIVNCERGFLHLAVPRHGGNRAFYNPYDEMILTLVLYELLVITLLYT
>NZ_CP011114.1|WP_025694355.1|592965_593739_+|sporulation-protein
MSMFKKVLASVGIGSAKVDTRLEEARVVAGGTLRGVVSIRGGQVEQQIDKIYIYVKTQYDKEENDRKITHETEIARILITEGFLLQAGEVREIPFEITVPERTPVSYRHTPVWLMTGLDIKMALDPSDHDYLEVLPSDNMQVVFGALDELGFRLREVSNEYAPRLGAGLPFVQEFEYVPTREFRGALDELEVMFFPRGDNLELYIQIDRRARGLGGFLSEAMGTDESFIRVTFTGNDLRRGVHEVSNQLYELISRYS
>NZ_CP011114.1|WP_025694356.1|592521_592854_+|chaperone-CsaA
MATFDDFLKLDIRVGTIIKAEFFAKAKVPAIKLEIDFGQEIGIKTSSAQITKRYTAEDIIGQQIIGVVNFPPRRIAGFNSEVLVLGGIPEKGDVVLLKPDFKLPDGTPIG
>NZ_CP011114.1|WP_025694814.1|604519_604990_+|ribose-5-phosphate-isomerase-B
MKIAVAGDHAGFSLKEEVKALLTSQGHEVVDFGTHSEEASDLPDYIYPAALAVAEGKADRGIFIDGVGYGSAMIANKIYGVYAAVCQDPFCAELARSHSDTNVLCIGGKIIGSAIALEIVKVWMTTDHLGDVEKYKRRVDKVVEISEKHLKKLSEL
>NZ_CP011114.1|WP_025694815.1|605107_605320_-|DUF86-domain-containing-protein
MNRDILLNKTENIRICIIFNLQRCCEACIELAMHSVSELKLGVSQSSRDAFEMLYNKGIIDEKLKEYMSR
>NZ_CP011114.1|WP_025694817.1|606115_606577_+|hypothetical-protein
MDKLTLTEAQLREIVDSYDMQHEGIDSFFNLESKEVVFVNNEFSDPEDEELEEEIEEGFGEIWFRLPERYSSDGYRDMEDFVDIVSDERLRELLITSLRGGRGFFRRFKDTLGDNPEELERYYQFVYERNRERVLKWMEAEFDLEIEIIGGED
>NZ_CP011114.1|WP_025694818.1|606927_608016_+|outer-membrane-lipoprotein-carrier-protein-LolA
MRRIAWVLAIIMSVTLIMTGCGKKDSASVVKDLNDVADKLESKTGAYQGEGTMTLYTGEQPQEYRVEVWYKNPSYYRISLANVQKNITQIVLRNDEGVFVLTPSLGKSFRFQSDWPDKQGQVYLYQTLVKGIVADNNRQFVADKDSYVFEVAANYQSSALVRQKIWLDKKTYAPKQVQVSDSEAKVVVDVKFNKFAFNPEFSADSFDMQKNMASGGNSKNTVAQVDENGNPLPAADNQEGTQAQANAALGDFGIIEPGYTPEGVTFKDSNKVENSDNHAVLLRYDGIYQYTIMESRPLDQAVSLAPGTLIDLGFTAGLLTGDEQQTLTWMSGDGVEFRITSANLPPSEMMEIAASMQDQTGK
>NZ_CP011114.1|WP_025694819.1|608241_609444_+|alanine-racemase
MQESYRPTVAEIDLDALRANYESFRRHLPAGVKFMACVKGNAYGHGAVEVTRELERLGADYVSVAFLDEAIELRQAGIVLPILVLGYTPPEAIAAAWENDVTVTLFTPEGLEAASKLPLNDSRKLKVHIKIDSGMGRLGLLPDDVPLFIEEAQRVRQIELEGMFTHFAKADEADKSYTLEQYRRFMGVTEALRERQIHIPIIHTGNSATAIDTPHLSPNMVRVGVSIYGFYPSTEVNRQQVKLHPVMTLKTKAVYVKSLPESWGVSYGTRYRADNGEYIATLPIGYADGYSRMLSGKAEVLIRGRRVPVVGTICMDQCMVSLKSFANEAEQIKAGEEVVLIGRQAGVSITADELALLLGTIHYEVTCMLAHRVPRVYIREGSAPRLVNALLQAPSPNPVS
>NZ_CP011114.1|WP_175491834.1|609668_609920_+|ribbon-helix-helix-protein,-CopG-family
MISLPDHLLQEVDGIVQMENSNRSELIRQAMKLYLSERRKRSIRESMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLVSGV
>NZ_CP011114.1|WP_025691534.1|609923_610274_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDASSHGFDRDSVILLEQVRTIDKQRLTDKITHLDDETMKKVDDSLQISLGLIDF
>NZ_CP011114.1|WP_025694820.1|610476_612666_+|RNA-binding-transcriptional-accessory-protein
MNIVSDEAARRERQMMIGQIAKELGLSERQVGTTAGLLDEGNTIPFIARYRKEMTGELDENALRDIEERLSYLRSLGERKREVIRIIEEQGKLTDELREQIAGAVKLQEVEDLYRPYRQKRKTRASVAKEKGLGPLADWIMEQRRGGNPEAEAGKYVDPAKGVESAEQALQGAQDIIAEAIADDAAVRSWVRQFTASQGILVSEAKDKEQESVYENYYSYREPVHKMPPHRILAINRGERENVLKVSIEVDAARIHAHITRKLVKGPSPVKELLEAVAEDAYKRLIAPSVEREVRGEMTEKGENQAISIFSGNLRSLLLQPPVKGRRVLGVDPAYRTGCKLAVVDETGKLLEVAVTYPTPPHNKKREAAEKFKELIAKYGIQLIVIGNGTGSRETEQFTAETIAEIGDPGLAYLIVNEAGASVYSASKLAQEEFPDLDVAERSAASIARRVQDPLAELVKIEPKAIGVGQYQHDVSQKHLDESLTAVVESAVNHVGVDVNTASPSLLSYVAGINSTIAKNIVKFREENGSFKNRKQLQKVPRLGAKSYEQCIGFLRIPEGENTLDRTPIHPESYDVVSRLFKELGLALSQIGSKELAAELAAQNPEELAARLDVGVPTLRDILESLQRPGRDPREELPPPIFRTDVLKIEDLAPGMELQGTVRNVIDFGAFVDIGIKNDGLVHISQLSSSFVKHPMDVVSVGDNVTVWVLSVDLKKGRVSLTMRPPRGE
>NZ_CP011114.1|WP_025695199.1|612813_613785_-|S-layer-homology-domain-containing-protein
MMKRQTFRHNAKKMTIACGILAGAVLFGASAFAFSDLKGDPAEAKINALHEAGVINGVTSQLFAPKSKMTYGQAVQLIVSGLALKTNPVPGSPSKASDYFAKVDDKSWYAPSLLIAVQNGLPLDKAVNPNAAVSRATFAQLLDAALKAKGDFPVTEMYFNIADGGKLSAEVNGSLQTLLNMRIISLDPGGKFRPNDAVTRSEAAAWVHDARAFVQSMFGGDGSADTSQGADINVEKAADGVNKVSVTVGNLPNPGYGLTIAKIEFGEGKKAVIYYEVTKPGPGMYPQVISKATAVAYLPEGYVASAKPMPGSYTPPEPDSPQF
>NZ_CP011114.1|WP_025695200.1|616193_618635_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRQKDKKIQTVEEHQKEVQVGCEQYGAKIGVTHLAGLAGMLHDIGKNTNEFNTYLVKAVYHPEAASRKGSVDHSTAGGKLLYQRYHKGEGVSMNKLAAEWIGNCIISHHQGLRDFLSPQLDSPYLKRVGQKELDEYDRAVAAFFEQVPADKLDRYFEQAVAELKLALTIIQEYKLPRITLALLIKYIFSCLIDADRTNTRDFEADEHTDWIKDHQSFFLESYNRLLAKIALLNEAKDADHPINRLRREMSRQCEEFALLSSGIYTLSIPTGGGKTLASLRYALRHALETGKERIIYIVPFTTIIEQNAKEIREIIQNDDMVLEHHSNVVDEIDPGSDDYDLEKEKLKLARDHWDRPIIFTTMVQFLNTFYAKGTRNVRRLHQLSNAVLIFDEVQAVPHRCLSLFNAALNFLHTFGKSSIVLCTATQPALDDVRHKLHLSEQSEMIKNLSDVGRYFKRVELVDYTAKCGASGWGAETLASFVRERMNEVNSVLVILNTKTAVRKLFAELDQEEWAEDRKVRLFHLSTNMCAAHRKDVLAELIQVLDSKVNERVICVSTQLIEAGVNISFDCVIRSLSGLDSITQAAGRCNRHGKDPLRQVYVIQSADENLNHLQEIKIGAEMTLKVLDDFRKKPELYENDRLSPSAMKAYFKYYYHRIKDELDYPVPKLGGKKLFNLLSSNKAYYDAYRNRYSEKLGLGSLQALATAEQYFEVIDNPATSVIVPYNAEARDLIANLNGELDIWELGDLLRKAQQYVVNVYKHDLVKLDKSGELFPLLNGNVLALHDTAYSERFGVGTEGDGEWGTSII

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Crispr_ID: NZ_CP011114_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_3

602580-603821

TypeI

I-C

Consensus_repeat	Method
GTCGCTCTCCATGCGAGAGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CRT

18 spacers

cas3

The CRISPR arrays of NZ_CP011114_3

>merge|NZ_CP011114|3|602580-603821|CRISPRCasFinder,CRT
GTCGCTCCCCATGTGGGAGCGTGGATTGAAATTATCGAAAGTATCAAATGTGCCGGTCTCTTCGCCCTCGTCGCTCCCCATGTGGGAGCGTGGATTGAAATACTTGTTCGTCCTCCTTTTTTTGAAGCGCAGAATACAGTCGCTCCCCATGTGGGAGCGTGGATTGAAATGTTTGATTCGTCATCACTTATCCCTCCCGCGTATGGTCGCTCCCCATGTGGGAGCGTGGATTGAAATCAGCAACAGCGCTGATGTTTCCTGGTGTGAGATACGTCGCTCCCCATGTGGGAGCGTGGATTGAAATTTACGCTTAAACGGCCACATCCGTAATCACCTCCGCGTCGCTCCCCATGTGGGAGCGTGGATTGAAATAGGCGGCCATTAAGATGACGAATGACCAGCTTGGTCGCTCCCCATGTGGGAGCGTGGATTGAAATCATACCGCCTTGCCGCTTGCGTAGAACGTGTGTACGTCGCTCCCCATGTGGGAGCGTGGATTGAAATCATTCTGCAAATCTATCCCACCTTAATAGGCACGGGTCGCTCCCCATGTGGGAGCGTGGATTGAAATAGACCATTGCTAACGTGGACAGCCAGAGACGTATTCGAGTCGCTCCCCATGTGGGAGCGTGGATTGAAATAATGCTTTGAAGACACTGTCCAAAATCTTTTGTTGTCGCTCCCCATGTGGGAGCGTGGATTGAAATCTCAGACCAGTCTGCAAATTTTACGATGTTTTTCCGTCGCTCCCCATGTGGGAGCGTGGATTGAAATCGAACTCAAAGACGTTGCTGGAAAGGTTGTTAATGTCGCTCCCCATGTGGGAGCGTGGATTGAAATTTCGGTGCGGCGGATGTTACGGGCCAACATGAGGCCGTCGCTCCCCATGTGGGAGCGTGGATTGAAATCGAATCAACAAAGGCAATCGATACAAATGGGGATTGGTCGCTCCCCATGCGGGAGCGTGGATTGAAATTTCTATATAAATTAACATGTCCGTATCATATTAGTCGCTCCCCATGCGGGAGCGTGGATTGAAATCATAAATTCACATTAAAGTAAGTGATTTTTGTCGTCGCTCCCCATGCGGGAGCGTGGATTGAAATCATTCATGGTACAGGGCTTCTTGCAGCGTTTCGTAGTCGCACCCCGTGCGGGTGCGTGGATTGAAATAGCAATCCGACACTGGGCTAATCACTAAAACTTAGGGTCGCACCCCGTGCGGGAGCGTGGATTGAAATG

>NZ_CP011114|3|3|602580-603821|CRISPRCasFinder
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	TATCGAAAGTATCAAATGTGCCGGTCTCTTCGCCCTC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	ACTTGTTCGTCCTCCTTTTTTTGAAGCGCAGAATACA
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	GTTTGATTCGTCATCACTTATCCCTCCCGCGTATG
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CAGCAACAGCGCTGATGTTTCCTGGTGTGAGATAC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	TTACGCTTAAACGGCCACATCCGTAATCACCTCCGC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	AGGCGGCCATTAAGATGACGAATGACCAGCTTG
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CATACCGCCTTGCCGCTTGCGTAGAACGTGTGTAC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CATTCTGCAAATCTATCCCACCTTAATAGGCACGG
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	AGACCATTGCTAACGTGGACAGCCAGAGACGTATTCGA
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	AATGCTTTGAAGACACTGTCCAAAATCTTTTGTT
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CTCAGACCAGTCTGCAAATTTTACGATGTTTTTCC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CGAACTCAAAGACGTTGCTGGAAAGGTTGTTAAT
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	TTCGGTGCGGCGGATGTTACGGGCCAACATGAGGCC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CGAATCAACAAAGGCAATCGATACAAATGGGGATTG
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	TTCTATATAAATTAACATGTCCGTATCATATTA
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	CATAAATTCACATTAAAGTAAGTGATTTTTGTC
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	CATTCATGGTACAGGGCTTCTTGCAGCGTTTCGTA
GTCGCACCCCGTGCGGGTGCGTGGATTGAAAT	AGCAATCCGACACTGGGCTAATCACTAAAACTTAGG
GTCGCACCCCGTGCGGGAGCGTGGATTGAAATG

>NZ_CP011114|3|3|602580-603820|CRT
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	TATCGAAAGTATCAAATGTGCCGGTCTCTTCGCCCTC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	ACTTGTTCGTCCTCCTTTTTTTGAAGCGCAGAATACA
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	GTTTGATTCGTCATCACTTATCCCTCCCGCGTATG
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CAGCAACAGCGCTGATGTTTCCTGGTGTGAGATAC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	TTACGCTTAAACGGCCACATCCGTAATCACCTCCGC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	AGGCGGCCATTAAGATGACGAATGACCAGCTTG
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CATACCGCCTTGCCGCTTGCGTAGAACGTGTGTAC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CATTCTGCAAATCTATCCCACCTTAATAGGCACGG
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	AGACCATTGCTAACGTGGACAGCCAGAGACGTATTCGA
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	AATGCTTTGAAGACACTGTCCAAAATCTTTTGTT
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CTCAGACCAGTCTGCAAATTTTACGATGTTTTTCC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CGAACTCAAAGACGTTGCTGGAAAGGTTGTTAAT
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	TTCGGTGCGGCGGATGTTACGGGCCAACATGAGGCC
GTCGCTCCCCATGTGGGAGCGTGGATTGAAAT	CGAATCAACAAAGGCAATCGATACAAATGGGGATTG
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	TTCTATATAAATTAACATGTCCGTATCATATTA
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	CATAAATTCACATTAAAGTAAGTGATTTTTGTC
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	CATTCATGGTACAGGGCTTCTTGCAGCGTTTCGTA
GTCGCACCCCGTGCGGGTGCGTGGATTGAAAT	AGCAATCCGACACTGGGCTAATCACTAAAACTTAGG
GTCGCACCCCGTGCGGGAGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025694356.1\|592521_592854_+\|chaperone-CsaA	unknown	unknown	gnl\|CDD\|182232
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380358
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	unknown	unknown	gnl\|CDD\|289015
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|225390
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP011114.1\|WP_036638762.1\|599337_599511_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|366864
NZ_CP011114.1\|WP_025694349.1\|598918_599197_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|223963
NZ_CP011114.1\|WP_025694355.1\|592965_593739_+\|sporulation-protein	unknown	unknown	gnl\|CDD\|369195
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl\|CDD\|376799
NZ_CP011114.1\|WP_025694354.1\|594072_594381_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|308978
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|183582

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025694356.1\|592521_592854_+\|chaperone-CsaA	gnl\|CDD\|182232	PRK10089, PRK10089, chaperone CsaA.	1.25664e-62
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	1.54473e-09
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	gnl\|CDD\|289015	pfam12207, DUF3600, Domain of unknown function (DUF3600). This family of proteins is found in bacteria. Proteins in this family are approximately 230 amino acids in length. This domain is the C terminal of the putative ecf-type sigma factor negative effector.	4.8938e-08
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.71168e-06
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	1.90047e-25
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	4.92745e-41
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.01583e-17
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	1.19044e-05
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	gnl\|CDD\|366864	pfam01934, DUF86, Protein of unknown function DUF86. The function of members of this family is unknown.	0.00129737
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	1.50575e-33
NZ_CP011114.1\|WP_025694355.1\|592965_593739_+\|sporulation-protein	gnl\|CDD\|369195	pfam07070, Spo0M, SpoOM protein. This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH.	3.36751e-104
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	gnl\|CDD\|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	2.66566e-62
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	gnl\|CDD\|308978	pfam03682, UPF0158, Uncharacterized protein family (UPF0158).	2.63302e-07
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.76854e-66
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|183582	PRK12543, PRK12543, RNA polymerase sigma factor; Provisional.	2.07712e-64

>NZ_CP011114.1|WP_025694813.1|601476_601713_-|helix-turn-helix-transcriptional-regulator
MEYNRYTLHCKLDEILKEHDNMSVLKLSKEIGHRRTTIMELMHNTNMEKKKISAALIVKLCLYFDISPNELFEVRPKE
>NZ_CP011114.1|WP_036638762.1|599337_599511_+|hypothetical-protein
MATDKRVFTLRLKEENFDKIKYIADKNKRSIAMQIEYLIEQHIEHFEKEKGIIKTDE
>NZ_CP011114.1|WP_025694349.1|598918_599197_-|hypothetical-protein
MAYMEQAFNQFLSARMEYIANSILSNCNEYRQLIEECNQLFLTLMTDLPQEYKEMLQNYDTSTALLQGIAETLMYKQGLKDGISLNRFLTDR
>NZ_CP011114.1|WP_025694350.1|597757_598099_-|cupin-domain-containing-protein
MEKKELVQFQEYQTDRFTKRIVFKEDKHTVFVLNFGPGQQLPVHKHPGASVYILFLEGSGIVTSDGREISVSQGDVVQISGDEDFSYRSGEGSNSSLYVTLINTPGEQYAQNI
>NZ_CP011114.1|WP_025694351.1|596804_597548_+|DUF3600-domain-containing-protein
MKLEQELREALREESRAWTAPLELKDRILNHKSLNPEGRRMKKWIAAGILAAVLLVPTGAYAGYHYLADSVYGSQERIEPFGGTQQYDYLEEKLQAAKQSFEPQEFAKLMGMLKKLGDYNLKIADDTGVLHPERLSPADQETYKKLNAELEPYFEKLNERVTAKEAVRQVDNVWKDVLARGEQNLSSQDFAKVKGVISGIQKLQAQAARPDGTDRAFTKEEKEQLKELVRQLEPYQDQLGIMLKPVK
>NZ_CP011114.1|WP_025694352.1|596233_596815_+|sigma-70-family-RNA-polymerase-sigma-factor
MNHPKQDSELAALVLAGSREAYSELYEKTITEVYRTVRFLIGESSDTDDVVQEIYIQAYRSLGQYDAARPFRPWLMGVVMRQIRSYRRKSWNHIRLIKKAQQSIALAYDFSGEVVDKISNRPLIASVERLPFKLKQVVILHYLNEYSQEEIADALDIPLGTVKSRIHAALKKLRSKRSSEILLRGKVEDLHEA
>NZ_CP011114.1|WP_025694353.1|594593_595871_+|B12-binding-domain-containing-radical-SAM-protein
MRKKILLIQPENEKINRFRRKQFNNFVQITMPYLAGFIDESKYQITLIDEYRQKIPFRRTFDLVAITVNTPNAYHCYQIAEKFRAQGAKVVMGGPHVTLLPEEASGHCDSILIGEAEETWPEFLDDFHKGKERAVYRSEGIPDLKNLPLPRWDLLKRNRLMKGAVFATRGCPYRCAYCNLKQIYHDRFRVRPIPEVIREISLMKSRFFVFWDDNFFADKAHATELMENLKPLGKKWAAQVTLADCNDDELLERAREAGCLYLFVGLESFSPSALRGVNKGINRVDSYREIIGKLHGHKIMIQAGIVFGFDEDTPATFRDTLAACEELGIDGVTVSLLTPLPRTPVYAGMKQEQRLLSGDWSLYNGKTDVVFGPRNMTSEQLFEGYLDFRRRFYSLPSFIRRMRVSRTHLFYNFIINLGYRLALKR
>NZ_CP011114.1|WP_025694354.1|594072_594381_-|hypothetical-protein
MSIQMGVPQQQVLYQADSQSIQNLKSIRSHLHNICRQHTNQYVRIETIDGQVVTGRIVNCERGFLHLAVPRHGGNRAFYNPYDEMILTLVLYELLVITLLYT
>NZ_CP011114.1|WP_025694355.1|592965_593739_+|sporulation-protein
MSMFKKVLASVGIGSAKVDTRLEEARVVAGGTLRGVVSIRGGQVEQQIDKIYIYVKTQYDKEENDRKITHETEIARILITEGFLLQAGEVREIPFEITVPERTPVSYRHTPVWLMTGLDIKMALDPSDHDYLEVLPSDNMQVVFGALDELGFRLREVSNEYAPRLGAGLPFVQEFEYVPTREFRGALDELEVMFFPRGDNLELYIQIDRRARGLGGFLSEAMGTDESFIRVTFTGNDLRRGVHEVSNQLYELISRYS
>NZ_CP011114.1|WP_025694356.1|592521_592854_+|chaperone-CsaA
MATFDDFLKLDIRVGTIIKAEFFAKAKVPAIKLEIDFGQEIGIKTSSAQITKRYTAEDIIGQQIIGVVNFPPRRIAGFNSEVLVLGGIPEKGDVVLLKPDFKLPDGTPIG
>NZ_CP011114.1|WP_025694814.1|604519_604990_+|ribose-5-phosphate-isomerase-B
MKIAVAGDHAGFSLKEEVKALLTSQGHEVVDFGTHSEEASDLPDYIYPAALAVAEGKADRGIFIDGVGYGSAMIANKIYGVYAAVCQDPFCAELARSHSDTNVLCIGGKIIGSAIALEIVKVWMTTDHLGDVEKYKRRVDKVVEISEKHLKKLSEL
>NZ_CP011114.1|WP_025694815.1|605107_605320_-|DUF86-domain-containing-protein
MNRDILLNKTENIRICIIFNLQRCCEACIELAMHSVSELKLGVSQSSRDAFEMLYNKGIIDEKLKEYMSR
>NZ_CP011114.1|WP_025694817.1|606115_606577_+|hypothetical-protein
MDKLTLTEAQLREIVDSYDMQHEGIDSFFNLESKEVVFVNNEFSDPEDEELEEEIEEGFGEIWFRLPERYSSDGYRDMEDFVDIVSDERLRELLITSLRGGRGFFRRFKDTLGDNPEELERYYQFVYERNRERVLKWMEAEFDLEIEIIGGED
>NZ_CP011114.1|WP_025694818.1|606927_608016_+|outer-membrane-lipoprotein-carrier-protein-LolA
MRRIAWVLAIIMSVTLIMTGCGKKDSASVVKDLNDVADKLESKTGAYQGEGTMTLYTGEQPQEYRVEVWYKNPSYYRISLANVQKNITQIVLRNDEGVFVLTPSLGKSFRFQSDWPDKQGQVYLYQTLVKGIVADNNRQFVADKDSYVFEVAANYQSSALVRQKIWLDKKTYAPKQVQVSDSEAKVVVDVKFNKFAFNPEFSADSFDMQKNMASGGNSKNTVAQVDENGNPLPAADNQEGTQAQANAALGDFGIIEPGYTPEGVTFKDSNKVENSDNHAVLLRYDGIYQYTIMESRPLDQAVSLAPGTLIDLGFTAGLLTGDEQQTLTWMSGDGVEFRITSANLPPSEMMEIAASMQDQTGK
>NZ_CP011114.1|WP_025694819.1|608241_609444_+|alanine-racemase
MQESYRPTVAEIDLDALRANYESFRRHLPAGVKFMACVKGNAYGHGAVEVTRELERLGADYVSVAFLDEAIELRQAGIVLPILVLGYTPPEAIAAAWENDVTVTLFTPEGLEAASKLPLNDSRKLKVHIKIDSGMGRLGLLPDDVPLFIEEAQRVRQIELEGMFTHFAKADEADKSYTLEQYRRFMGVTEALRERQIHIPIIHTGNSATAIDTPHLSPNMVRVGVSIYGFYPSTEVNRQQVKLHPVMTLKTKAVYVKSLPESWGVSYGTRYRADNGEYIATLPIGYADGYSRMLSGKAEVLIRGRRVPVVGTICMDQCMVSLKSFANEAEQIKAGEEVVLIGRQAGVSITADELALLLGTIHYEVTCMLAHRVPRVYIREGSAPRLVNALLQAPSPNPVS
>NZ_CP011114.1|WP_175491834.1|609668_609920_+|ribbon-helix-helix-protein,-CopG-family
MISLPDHLLQEVDGIVQMENSNRSELIRQAMKLYLSERRKRSIRESMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLVSGV
>NZ_CP011114.1|WP_025691534.1|609923_610274_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDASSHGFDRDSVILLEQVRTIDKQRLTDKITHLDDETMKKVDDSLQISLGLIDF
>NZ_CP011114.1|WP_025694820.1|610476_612666_+|RNA-binding-transcriptional-accessory-protein
MNIVSDEAARRERQMMIGQIAKELGLSERQVGTTAGLLDEGNTIPFIARYRKEMTGELDENALRDIEERLSYLRSLGERKREVIRIIEEQGKLTDELREQIAGAVKLQEVEDLYRPYRQKRKTRASVAKEKGLGPLADWIMEQRRGGNPEAEAGKYVDPAKGVESAEQALQGAQDIIAEAIADDAAVRSWVRQFTASQGILVSEAKDKEQESVYENYYSYREPVHKMPPHRILAINRGERENVLKVSIEVDAARIHAHITRKLVKGPSPVKELLEAVAEDAYKRLIAPSVEREVRGEMTEKGENQAISIFSGNLRSLLLQPPVKGRRVLGVDPAYRTGCKLAVVDETGKLLEVAVTYPTPPHNKKREAAEKFKELIAKYGIQLIVIGNGTGSRETEQFTAETIAEIGDPGLAYLIVNEAGASVYSASKLAQEEFPDLDVAERSAASIARRVQDPLAELVKIEPKAIGVGQYQHDVSQKHLDESLTAVVESAVNHVGVDVNTASPSLLSYVAGINSTIAKNIVKFREENGSFKNRKQLQKVPRLGAKSYEQCIGFLRIPEGENTLDRTPIHPESYDVVSRLFKELGLALSQIGSKELAAELAAQNPEELAARLDVGVPTLRDILESLQRPGRDPREELPPPIFRTDVLKIEDLAPGMELQGTVRNVIDFGAFVDIGIKNDGLVHISQLSSSFVKHPMDVVSVGDNVTVWVLSVDLKKGRVSLTMRPPRGE
>NZ_CP011114.1|WP_025695199.1|612813_613785_-|S-layer-homology-domain-containing-protein
MMKRQTFRHNAKKMTIACGILAGAVLFGASAFAFSDLKGDPAEAKINALHEAGVINGVTSQLFAPKSKMTYGQAVQLIVSGLALKTNPVPGSPSKASDYFAKVDDKSWYAPSLLIAVQNGLPLDKAVNPNAAVSRATFAQLLDAALKAKGDFPVTEMYFNIADGGKLSAEVNGSLQTLLNMRIISLDPGGKFRPNDAVTRSEAAAWVHDARAFVQSMFGGDGSADTSQGADINVEKAADGVNKVSVTVGNLPNPGYGLTIAKIEFGEGKKAVIYYEVTKPGPGMYPQVISKATAVAYLPEGYVASAKPMPGSYTPPEPDSPQF
>NZ_CP011114.1|WP_025695200.1|616193_618635_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRQKDKKIQTVEEHQKEVQVGCEQYGAKIGVTHLAGLAGMLHDIGKNTNEFNTYLVKAVYHPEAASRKGSVDHSTAGGKLLYQRYHKGEGVSMNKLAAEWIGNCIISHHQGLRDFLSPQLDSPYLKRVGQKELDEYDRAVAAFFEQVPADKLDRYFEQAVAELKLALTIIQEYKLPRITLALLIKYIFSCLIDADRTNTRDFEADEHTDWIKDHQSFFLESYNRLLAKIALLNEAKDADHPINRLRREMSRQCEEFALLSSGIYTLSIPTGGGKTLASLRYALRHALETGKERIIYIVPFTTIIEQNAKEIREIIQNDDMVLEHHSNVVDEIDPGSDDYDLEKEKLKLARDHWDRPIIFTTMVQFLNTFYAKGTRNVRRLHQLSNAVLIFDEVQAVPHRCLSLFNAALNFLHTFGKSSIVLCTATQPALDDVRHKLHLSEQSEMIKNLSDVGRYFKRVELVDYTAKCGASGWGAETLASFVRERMNEVNSVLVILNTKTAVRKLFAELDQEEWAEDRKVRLFHLSTNMCAAHRKDVLAELIQVLDSKVNERVICVSTQLIEAGVNISFDCVIRSLSGLDSITQAAGRCNRHGKDPLRQVYVIQSADENLNHLQEIKIGAEMTLKVLDDFRKKPELYENDRLSPSAMKAYFKYYYHRIKDELDYPVPKLGGKKLFNLLSSNKAYYDAYRNRYSEKLGLGSLQALATAEQYFEVIDNPATSVIVPYNAEARDLIANLNGELDIWELGDLLRKAQQYVVNVYKHDLVKLDKSGELFPLLNGNVLALHDTAYSERFGVGTEGDGEWGTSII

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Crispr_ID: NZ_CP011114_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_5

605813-606043

TypeI

I-C

Consensus_repeat	Method
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAATACCG	PILER-CR
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	CRT

3 spacers

cas3,cas5,cas8c

The CRISPR arrays of NZ_CP011114_5

>merge|NZ_CP011114|5|605813-606043|PILER-CR,CRISPRCasFinder,CRT
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAATGCCGCATTATTAGAGGCGGGACGCTCATGCCGCAGTCGCTCCCCGTGCGGGAGCGTGGATTGAAATTAGTCAAACATCGTGGAAAGTCCCCATAGAACTGGGTCGCTCCCCGTGCGGGAGCGTGGATTGAAATACCGAACCGCGTCTTGCCCGTCAGCAACCATCTCGTCGCTCCCCATACGGGAGCGTGGACTGAAAT

>NZ_CP011114|5|4|605813-605981|PILER-CR
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAATGCCG	CATTATTAGAGGCGGGACGCTCATGCCGCA
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAATTAGT	CAAACATCGTGGAAAGTCCCCATAGAACTGGGTCG
CTCCCCGTGCGGGAGCGTGGATTGAAATACCG

>NZ_CP011114|5|5|605813-606043|CRISPRCasFinder
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	GCCGCATTATTAGAGGCGGGACGCTCATGCCGCA
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	TAGTCAAACATCGTGGAAAGTCCCCATAGAACTGG
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	ACCGAACCGCGTCTTGCCCGTCAGCAACCATCTC
GTCGCTCCCCATACGGGAGCGTGGACTGAAAT

>NZ_CP011114|5|5|605813-606043|CRT
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	GCCGCATTATTAGAGGCGGGACGCTCATGCCGCA
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	TAGTCAAACATCGTGGAAAGTCCCCATAGAACTGG
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	ACCGAACCGCGTCTTGCCCGTCAGCAACCATCTC
GTCGCTCCCCATACGGGAGCGTGGACTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380358
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	unknown	unknown	gnl\|CDD\|289015
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|183582
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|225390
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP011114.1\|WP_036638762.1\|599337_599511_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|366864
NZ_CP011114.1\|WP_025694349.1\|598918_599197_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|223963
NZ_CP011114.1\|WP_025695202.1\|619955_621905_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl\|CDD\|376799
NZ_CP011114.1\|WP_025695201.1\|619236_619959_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP011114.1\|WP_025694354.1\|594072_594381_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|308978
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025694350.1\|597757_598099_-\|cupin-domain-containing-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	1.54473e-09
NZ_CP011114.1\|WP_025694351.1\|596804_597548_+\|DUF3600-domain-containing-protein	gnl\|CDD\|289015	pfam12207, DUF3600, Domain of unknown function (DUF3600). This family of proteins is found in bacteria. Proteins in this family are approximately 230 amino acids in length. This domain is the C terminal of the putative ecf-type sigma factor negative effector.	4.8938e-08
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.71168e-06
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	1.90047e-25
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	4.92745e-41
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.01583e-17
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	1.19044e-05
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	gnl\|CDD\|366864	pfam01934, DUF86, Protein of unknown function DUF86. The function of members of this family is unknown.	0.00129737
NZ_CP011114.1\|WP_025695202.1\|619955_621905_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	5.13918e-171
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP011114.1\|WP_025694353.1\|594593_595871_+\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	1.50575e-33
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	gnl\|CDD\|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	2.66566e-62
NZ_CP011114.1\|WP_025695201.1\|619236_619959_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	2.36826e-92
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	gnl\|CDD\|308978	pfam03682, UPF0158, Uncharacterized protein family (UPF0158).	2.63302e-07
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.76854e-66
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NZ_CP011114.1\|WP_025694352.1\|596233_596815_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|183582	PRK12543, PRK12543, RNA polymerase sigma factor; Provisional.	2.07712e-64

>NZ_CP011114.1|WP_025694815.1|605107_605320_-|DUF86-domain-containing-protein
MNRDILLNKTENIRICIIFNLQRCCEACIELAMHSVSELKLGVSQSSRDAFEMLYNKGIIDEKLKEYMSR
>NZ_CP011114.1|WP_025694814.1|604519_604990_+|ribose-5-phosphate-isomerase-B
MKIAVAGDHAGFSLKEEVKALLTSQGHEVVDFGTHSEEASDLPDYIYPAALAVAEGKADRGIFIDGVGYGSAMIANKIYGVYAAVCQDPFCAELARSHSDTNVLCIGGKIIGSAIALEIVKVWMTTDHLGDVEKYKRRVDKVVEISEKHLKKLSEL
>NZ_CP011114.1|WP_025694813.1|601476_601713_-|helix-turn-helix-transcriptional-regulator
MEYNRYTLHCKLDEILKEHDNMSVLKLSKEIGHRRTTIMELMHNTNMEKKKISAALIVKLCLYFDISPNELFEVRPKE
>NZ_CP011114.1|WP_036638762.1|599337_599511_+|hypothetical-protein
MATDKRVFTLRLKEENFDKIKYIADKNKRSIAMQIEYLIEQHIEHFEKEKGIIKTDE
>NZ_CP011114.1|WP_025694349.1|598918_599197_-|hypothetical-protein
MAYMEQAFNQFLSARMEYIANSILSNCNEYRQLIEECNQLFLTLMTDLPQEYKEMLQNYDTSTALLQGIAETLMYKQGLKDGISLNRFLTDR
>NZ_CP011114.1|WP_025694350.1|597757_598099_-|cupin-domain-containing-protein
MEKKELVQFQEYQTDRFTKRIVFKEDKHTVFVLNFGPGQQLPVHKHPGASVYILFLEGSGIVTSDGREISVSQGDVVQISGDEDFSYRSGEGSNSSLYVTLINTPGEQYAQNI
>NZ_CP011114.1|WP_025694351.1|596804_597548_+|DUF3600-domain-containing-protein
MKLEQELREALREESRAWTAPLELKDRILNHKSLNPEGRRMKKWIAAGILAAVLLVPTGAYAGYHYLADSVYGSQERIEPFGGTQQYDYLEEKLQAAKQSFEPQEFAKLMGMLKKLGDYNLKIADDTGVLHPERLSPADQETYKKLNAELEPYFEKLNERVTAKEAVRQVDNVWKDVLARGEQNLSSQDFAKVKGVISGIQKLQAQAARPDGTDRAFTKEEKEQLKELVRQLEPYQDQLGIMLKPVK
>NZ_CP011114.1|WP_025694352.1|596233_596815_+|sigma-70-family-RNA-polymerase-sigma-factor
MNHPKQDSELAALVLAGSREAYSELYEKTITEVYRTVRFLIGESSDTDDVVQEIYIQAYRSLGQYDAARPFRPWLMGVVMRQIRSYRRKSWNHIRLIKKAQQSIALAYDFSGEVVDKISNRPLIASVERLPFKLKQVVILHYLNEYSQEEIADALDIPLGTVKSRIHAALKKLRSKRSSEILLRGKVEDLHEA
>NZ_CP011114.1|WP_025694353.1|594593_595871_+|B12-binding-domain-containing-radical-SAM-protein
MRKKILLIQPENEKINRFRRKQFNNFVQITMPYLAGFIDESKYQITLIDEYRQKIPFRRTFDLVAITVNTPNAYHCYQIAEKFRAQGAKVVMGGPHVTLLPEEASGHCDSILIGEAEETWPEFLDDFHKGKERAVYRSEGIPDLKNLPLPRWDLLKRNRLMKGAVFATRGCPYRCAYCNLKQIYHDRFRVRPIPEVIREISLMKSRFFVFWDDNFFADKAHATELMENLKPLGKKWAAQVTLADCNDDELLERAREAGCLYLFVGLESFSPSALRGVNKGINRVDSYREIIGKLHGHKIMIQAGIVFGFDEDTPATFRDTLAACEELGIDGVTVSLLTPLPRTPVYAGMKQEQRLLSGDWSLYNGKTDVVFGPRNMTSEQLFEGYLDFRRRFYSLPSFIRRMRVSRTHLFYNFIINLGYRLALKR
>NZ_CP011114.1|WP_025694354.1|594072_594381_-|hypothetical-protein
MSIQMGVPQQQVLYQADSQSIQNLKSIRSHLHNICRQHTNQYVRIETIDGQVVTGRIVNCERGFLHLAVPRHGGNRAFYNPYDEMILTLVLYELLVITLLYT
>NZ_CP011114.1|WP_025694817.1|606115_606577_+|hypothetical-protein
MDKLTLTEAQLREIVDSYDMQHEGIDSFFNLESKEVVFVNNEFSDPEDEELEEEIEEGFGEIWFRLPERYSSDGYRDMEDFVDIVSDERLRELLITSLRGGRGFFRRFKDTLGDNPEELERYYQFVYERNRERVLKWMEAEFDLEIEIIGGED
>NZ_CP011114.1|WP_025694818.1|606927_608016_+|outer-membrane-lipoprotein-carrier-protein-LolA
MRRIAWVLAIIMSVTLIMTGCGKKDSASVVKDLNDVADKLESKTGAYQGEGTMTLYTGEQPQEYRVEVWYKNPSYYRISLANVQKNITQIVLRNDEGVFVLTPSLGKSFRFQSDWPDKQGQVYLYQTLVKGIVADNNRQFVADKDSYVFEVAANYQSSALVRQKIWLDKKTYAPKQVQVSDSEAKVVVDVKFNKFAFNPEFSADSFDMQKNMASGGNSKNTVAQVDENGNPLPAADNQEGTQAQANAALGDFGIIEPGYTPEGVTFKDSNKVENSDNHAVLLRYDGIYQYTIMESRPLDQAVSLAPGTLIDLGFTAGLLTGDEQQTLTWMSGDGVEFRITSANLPPSEMMEIAASMQDQTGK
>NZ_CP011114.1|WP_025694819.1|608241_609444_+|alanine-racemase
MQESYRPTVAEIDLDALRANYESFRRHLPAGVKFMACVKGNAYGHGAVEVTRELERLGADYVSVAFLDEAIELRQAGIVLPILVLGYTPPEAIAAAWENDVTVTLFTPEGLEAASKLPLNDSRKLKVHIKIDSGMGRLGLLPDDVPLFIEEAQRVRQIELEGMFTHFAKADEADKSYTLEQYRRFMGVTEALRERQIHIPIIHTGNSATAIDTPHLSPNMVRVGVSIYGFYPSTEVNRQQVKLHPVMTLKTKAVYVKSLPESWGVSYGTRYRADNGEYIATLPIGYADGYSRMLSGKAEVLIRGRRVPVVGTICMDQCMVSLKSFANEAEQIKAGEEVVLIGRQAGVSITADELALLLGTIHYEVTCMLAHRVPRVYIREGSAPRLVNALLQAPSPNPVS
>NZ_CP011114.1|WP_175491834.1|609668_609920_+|ribbon-helix-helix-protein,-CopG-family
MISLPDHLLQEVDGIVQMENSNRSELIRQAMKLYLSERRKRSIRESMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLVSGV
>NZ_CP011114.1|WP_025691534.1|609923_610274_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDASSHGFDRDSVILLEQVRTIDKQRLTDKITHLDDETMKKVDDSLQISLGLIDF
>NZ_CP011114.1|WP_025694820.1|610476_612666_+|RNA-binding-transcriptional-accessory-protein
MNIVSDEAARRERQMMIGQIAKELGLSERQVGTTAGLLDEGNTIPFIARYRKEMTGELDENALRDIEERLSYLRSLGERKREVIRIIEEQGKLTDELREQIAGAVKLQEVEDLYRPYRQKRKTRASVAKEKGLGPLADWIMEQRRGGNPEAEAGKYVDPAKGVESAEQALQGAQDIIAEAIADDAAVRSWVRQFTASQGILVSEAKDKEQESVYENYYSYREPVHKMPPHRILAINRGERENVLKVSIEVDAARIHAHITRKLVKGPSPVKELLEAVAEDAYKRLIAPSVEREVRGEMTEKGENQAISIFSGNLRSLLLQPPVKGRRVLGVDPAYRTGCKLAVVDETGKLLEVAVTYPTPPHNKKREAAEKFKELIAKYGIQLIVIGNGTGSRETEQFTAETIAEIGDPGLAYLIVNEAGASVYSASKLAQEEFPDLDVAERSAASIARRVQDPLAELVKIEPKAIGVGQYQHDVSQKHLDESLTAVVESAVNHVGVDVNTASPSLLSYVAGINSTIAKNIVKFREENGSFKNRKQLQKVPRLGAKSYEQCIGFLRIPEGENTLDRTPIHPESYDVVSRLFKELGLALSQIGSKELAAELAAQNPEELAARLDVGVPTLRDILESLQRPGRDPREELPPPIFRTDVLKIEDLAPGMELQGTVRNVIDFGAFVDIGIKNDGLVHISQLSSSFVKHPMDVVSVGDNVTVWVLSVDLKKGRVSLTMRPPRGE
>NZ_CP011114.1|WP_025695199.1|612813_613785_-|S-layer-homology-domain-containing-protein
MMKRQTFRHNAKKMTIACGILAGAVLFGASAFAFSDLKGDPAEAKINALHEAGVINGVTSQLFAPKSKMTYGQAVQLIVSGLALKTNPVPGSPSKASDYFAKVDDKSWYAPSLLIAVQNGLPLDKAVNPNAAVSRATFAQLLDAALKAKGDFPVTEMYFNIADGGKLSAEVNGSLQTLLNMRIISLDPGGKFRPNDAVTRSEAAAWVHDARAFVQSMFGGDGSADTSQGADINVEKAADGVNKVSVTVGNLPNPGYGLTIAKIEFGEGKKAVIYYEVTKPGPGMYPQVISKATAVAYLPEGYVASAKPMPGSYTPPEPDSPQF
>NZ_CP011114.1|WP_025695200.1|616193_618635_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRQKDKKIQTVEEHQKEVQVGCEQYGAKIGVTHLAGLAGMLHDIGKNTNEFNTYLVKAVYHPEAASRKGSVDHSTAGGKLLYQRYHKGEGVSMNKLAAEWIGNCIISHHQGLRDFLSPQLDSPYLKRVGQKELDEYDRAVAAFFEQVPADKLDRYFEQAVAELKLALTIIQEYKLPRITLALLIKYIFSCLIDADRTNTRDFEADEHTDWIKDHQSFFLESYNRLLAKIALLNEAKDADHPINRLRREMSRQCEEFALLSSGIYTLSIPTGGGKTLASLRYALRHALETGKERIIYIVPFTTIIEQNAKEIREIIQNDDMVLEHHSNVVDEIDPGSDDYDLEKEKLKLARDHWDRPIIFTTMVQFLNTFYAKGTRNVRRLHQLSNAVLIFDEVQAVPHRCLSLFNAALNFLHTFGKSSIVLCTATQPALDDVRHKLHLSEQSEMIKNLSDVGRYFKRVELVDYTAKCGASGWGAETLASFVRERMNEVNSVLVILNTKTAVRKLFAELDQEEWAEDRKVRLFHLSTNMCAAHRKDVLAELIQVLDSKVNERVICVSTQLIEAGVNISFDCVIRSLSGLDSITQAAGRCNRHGKDPLRQVYVIQSADENLNHLQEIKIGAEMTLKVLDDFRKKPELYENDRLSPSAMKAYFKYYYHRIKDELDYPVPKLGGKKLFNLLSSNKAYYDAYRNRYSEKLGLGSLQALATAEQYFEVIDNPATSVIVPYNAEARDLIANLNGELDIWELGDLLRKAQQYVVNVYKHDLVKLDKSGELFPLLNGNVLALHDTAYSERFGVGTEGDGEWGTSII
>NZ_CP011114.1|WP_025695201.1|619236_619959_+|type-I-C-CRISPR-associated-protein-Cas5
MRNQIEFEVYGKYGLFTDPLTKIGGEKFSYQIPTYQALKGIVESIYWKPTLIWIIDEVRVMEPIQTESKGIRPIEYGGGNTLSYYTYLKEPRYQVRAHFEFNPHREDLIQDRNEHKHHNIAKRAVQAGGRRDIFLGARECQGYVEPCEYGKGVGFYDEIAEIDFGIMVHGINYPDETGRQERETRLWRAKMEHGIIRYIRPEECTLLRKTGEGHIKSFGLADIQSVEELYADYFQGEERG
>NZ_CP011114.1|WP_025695202.1|619955_621905_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTWLADLYKTYENNAHLTGQFERKKNGREYALIPVSHTTQSSHIEVRLDMEGNLLQARVVEKEEASTIIPCTEASASRTSAPVPHPLFDKLVYVAGDYTRYYGEVKGTPHADYMKQLLAWCESPAAHSKVQSVYTYLSRGTLIADLVQREVLWLDEKGQLAPKWTPAMEQRYGEKKAIFKVIASDQSAAFIRFAVHVPGDPEDRLWRDRSVQEAFIRYNEMELAEQELCYVTGEYLPYADKHTSRIRNSGDKTKLISANDSLGFTYRGRFRSGREAAAVSYEVSQKGHNALKWLIDRQGVTIDGKVFLVWGIDNPDLPPPWEDGLDLYGEEEDEDTAGDAAHREFAGQFRRAIHGYRYNTDDYKSEVVIMVLDAATPGRLSIVYYRNLNKELFFNRLNYWHATCRWLHRYRKNEQKEILSFTGAPATRDIAFAAYGPQASDKVVKVLLERMLPCIVDKRPVPQDIVRSAVNRASNPVGMEPWEWEKTLSIACALVKKTYEKEGFTVSLDVENEDRSYLFGRMLAIADVLERRALGKEEKRATNAVRYMNVFAQHPGRTWEIIQSNLQPYQAKMGTKDGIINYCNKMLDEVGSRLKLEDYNDNRLNGRYLLGFYSQRNELYKSREQREAEAGQTARTDESANNDVQGENE

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Crispr_ID: NZ_CP011114_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_6

614027-614261

TypeI

I-C

Consensus_repeat	Method
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	PILER-CR
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT	CRT

3 spacers

cas3,cas5,cas8c,cas7,cas4,cas1,cas2

The CRISPR arrays of NZ_CP011114_6

>merge|NZ_CP011114|6|614027-614261|PILER-CR,CRISPRCasFinder,CRT
GTCGCTCCCCATGCGGGAGCGTGGATTGAAATTCACTCTTCGGGATGTAGCCAGAGAGGAAGGATTGAGTCGCTCCCCGTGTGGGAGCGTGGATTGAAATCTTTAGGTGTTCCGGTGTTCCTGTGGCTACTTTGGGTCGCTCCCCGTGCGGGAGTGTGGATTGAAATCGCAAAGGTCACGATTTTCGCTGGCGAAGCCATCGGTCGCTCCCCGTGCGGGAGCGTGGATTGAAATT

>NZ_CP011114|6|5|614027-614260|PILER-CR
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	TCACTCTTCGGGATGTAGCCAGAGAGGAAGGATTGA
GTCGCTCCCCGTGTGGGAGCGTGGATTGAAAT	CTTTAGGTGTTCCGGTGTTCCTGTGGCTACTTTGG
GTCGCTCCCCGTGCGGGAGTGTGGATTGAAAT	CGCAAAGGTCACGATTTTCGCTGGCGAAGCCATCG
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT

>NZ_CP011114|6|6|614027-614261|CRISPRCasFinder
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	TCACTCTTCGGGATGTAGCCAGAGAGGAAGGATTGA
GTCGCTCCCCGTGTGGGAGCGTGGATTGAAAT	CTTTAGGTGTTCCGGTGTTCCTGTGGCTACTTTGG
GTCGCTCCCCGTGCGGGAGTGTGGATTGAAAT	CGCAAAGGTCACGATTTTCGCTGGCGAAGCCATCG
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAATT

>NZ_CP011114|6|6|614027-614260|CRT
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	TCACTCTTCGGGATGTAGCCAGAGAGGAAGGATTGA
GTCGCTCCCCGTGTGGGAGCGTGGATTGAAAT	CTTTAGGTGTTCCGGTGTTCCTGTGGCTACTTTGG
GTCGCTCCCCGTGCGGGAGTGTGGATTGAAAT	CGCAAAGGTCACGATTTTCGCTGGCGAAGCCATCG
GTCGCTCCCCGTGCGGGAGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025695207.1\|627149_627896_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP011114.1\|WP_025695208.1\|627899_628811_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|238570
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|225390
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP011114.1\|WP_025695204.1\|622778_623438_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP011114.1\|WP_025695206.1\|624476_624767_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|366864
NZ_CP011114.1\|WP_025695202.1\|619955_621905_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP011114.1\|WP_025695203.1\|621904_622792_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP011114.1\|WP_025695205.1\|623434_624466_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl\|CDD\|376799
NZ_CP011114.1\|WP_046722766.1\|628874_630848_+\|PTS-fructose-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|236740
NZ_CP011114.1\|WP_025695201.1\|619236_619959_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|308978
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025695207.1\|627149_627896_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.48428e-82
NZ_CP011114.1\|WP_025695208.1\|627899_628811_+\|1-phosphofructokinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	7.69617e-137
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.71168e-06
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	1.90047e-25
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP011114.1\|WP_025695204.1\|622778_623438_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.03149e-28
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.01583e-17
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	1.19044e-05
NZ_CP011114.1\|WP_025695206.1\|624476_624767_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.3558e-30
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	gnl\|CDD\|366864	pfam01934, DUF86, Protein of unknown function DUF86. The function of members of this family is unknown.	0.00129737
NZ_CP011114.1\|WP_025695202.1\|619955_621905_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	5.13918e-171
NZ_CP011114.1\|WP_025695203.1\|621904_622792_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.31692e-125
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	4.92745e-41
NZ_CP011114.1\|WP_025695205.1\|623434_624466_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	gnl\|CDD\|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	2.66566e-62
NZ_CP011114.1\|WP_046722766.1\|628874_630848_+\|PTS-fructose-transporter-subunit-IIABC	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	1.71846e-135
NZ_CP011114.1\|WP_025695201.1\|619236_619959_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	2.36826e-92
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	gnl\|CDD\|308978	pfam03682, UPF0158, Uncharacterized protein family (UPF0158).	2.63302e-07
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.76854e-66
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0

>NZ_CP011114.1|WP_025695199.1|612813_613785_-|S-layer-homology-domain-containing-protein
MMKRQTFRHNAKKMTIACGILAGAVLFGASAFAFSDLKGDPAEAKINALHEAGVINGVTSQLFAPKSKMTYGQAVQLIVSGLALKTNPVPGSPSKASDYFAKVDDKSWYAPSLLIAVQNGLPLDKAVNPNAAVSRATFAQLLDAALKAKGDFPVTEMYFNIADGGKLSAEVNGSLQTLLNMRIISLDPGGKFRPNDAVTRSEAAAWVHDARAFVQSMFGGDGSADTSQGADINVEKAADGVNKVSVTVGNLPNPGYGLTIAKIEFGEGKKAVIYYEVTKPGPGMYPQVISKATAVAYLPEGYVASAKPMPGSYTPPEPDSPQF
>NZ_CP011114.1|WP_025694820.1|610476_612666_+|RNA-binding-transcriptional-accessory-protein
MNIVSDEAARRERQMMIGQIAKELGLSERQVGTTAGLLDEGNTIPFIARYRKEMTGELDENALRDIEERLSYLRSLGERKREVIRIIEEQGKLTDELREQIAGAVKLQEVEDLYRPYRQKRKTRASVAKEKGLGPLADWIMEQRRGGNPEAEAGKYVDPAKGVESAEQALQGAQDIIAEAIADDAAVRSWVRQFTASQGILVSEAKDKEQESVYENYYSYREPVHKMPPHRILAINRGERENVLKVSIEVDAARIHAHITRKLVKGPSPVKELLEAVAEDAYKRLIAPSVEREVRGEMTEKGENQAISIFSGNLRSLLLQPPVKGRRVLGVDPAYRTGCKLAVVDETGKLLEVAVTYPTPPHNKKREAAEKFKELIAKYGIQLIVIGNGTGSRETEQFTAETIAEIGDPGLAYLIVNEAGASVYSASKLAQEEFPDLDVAERSAASIARRVQDPLAELVKIEPKAIGVGQYQHDVSQKHLDESLTAVVESAVNHVGVDVNTASPSLLSYVAGINSTIAKNIVKFREENGSFKNRKQLQKVPRLGAKSYEQCIGFLRIPEGENTLDRTPIHPESYDVVSRLFKELGLALSQIGSKELAAELAAQNPEELAARLDVGVPTLRDILESLQRPGRDPREELPPPIFRTDVLKIEDLAPGMELQGTVRNVIDFGAFVDIGIKNDGLVHISQLSSSFVKHPMDVVSVGDNVTVWVLSVDLKKGRVSLTMRPPRGE
>NZ_CP011114.1|WP_025691534.1|609923_610274_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDASSHGFDRDSVILLEQVRTIDKQRLTDKITHLDDETMKKVDDSLQISLGLIDF
>NZ_CP011114.1|WP_175491834.1|609668_609920_+|ribbon-helix-helix-protein,-CopG-family
MISLPDHLLQEVDGIVQMENSNRSELIRQAMKLYLSERRKRSIRESMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLVSGV
>NZ_CP011114.1|WP_025694819.1|608241_609444_+|alanine-racemase
MQESYRPTVAEIDLDALRANYESFRRHLPAGVKFMACVKGNAYGHGAVEVTRELERLGADYVSVAFLDEAIELRQAGIVLPILVLGYTPPEAIAAAWENDVTVTLFTPEGLEAASKLPLNDSRKLKVHIKIDSGMGRLGLLPDDVPLFIEEAQRVRQIELEGMFTHFAKADEADKSYTLEQYRRFMGVTEALRERQIHIPIIHTGNSATAIDTPHLSPNMVRVGVSIYGFYPSTEVNRQQVKLHPVMTLKTKAVYVKSLPESWGVSYGTRYRADNGEYIATLPIGYADGYSRMLSGKAEVLIRGRRVPVVGTICMDQCMVSLKSFANEAEQIKAGEEVVLIGRQAGVSITADELALLLGTIHYEVTCMLAHRVPRVYIREGSAPRLVNALLQAPSPNPVS
>NZ_CP011114.1|WP_025694818.1|606927_608016_+|outer-membrane-lipoprotein-carrier-protein-LolA
MRRIAWVLAIIMSVTLIMTGCGKKDSASVVKDLNDVADKLESKTGAYQGEGTMTLYTGEQPQEYRVEVWYKNPSYYRISLANVQKNITQIVLRNDEGVFVLTPSLGKSFRFQSDWPDKQGQVYLYQTLVKGIVADNNRQFVADKDSYVFEVAANYQSSALVRQKIWLDKKTYAPKQVQVSDSEAKVVVDVKFNKFAFNPEFSADSFDMQKNMASGGNSKNTVAQVDENGNPLPAADNQEGTQAQANAALGDFGIIEPGYTPEGVTFKDSNKVENSDNHAVLLRYDGIYQYTIMESRPLDQAVSLAPGTLIDLGFTAGLLTGDEQQTLTWMSGDGVEFRITSANLPPSEMMEIAASMQDQTGK
>NZ_CP011114.1|WP_025694817.1|606115_606577_+|hypothetical-protein
MDKLTLTEAQLREIVDSYDMQHEGIDSFFNLESKEVVFVNNEFSDPEDEELEEEIEEGFGEIWFRLPERYSSDGYRDMEDFVDIVSDERLRELLITSLRGGRGFFRRFKDTLGDNPEELERYYQFVYERNRERVLKWMEAEFDLEIEIIGGED
>NZ_CP011114.1|WP_025694815.1|605107_605320_-|DUF86-domain-containing-protein
MNRDILLNKTENIRICIIFNLQRCCEACIELAMHSVSELKLGVSQSSRDAFEMLYNKGIIDEKLKEYMSR
>NZ_CP011114.1|WP_025694814.1|604519_604990_+|ribose-5-phosphate-isomerase-B
MKIAVAGDHAGFSLKEEVKALLTSQGHEVVDFGTHSEEASDLPDYIYPAALAVAEGKADRGIFIDGVGYGSAMIANKIYGVYAAVCQDPFCAELARSHSDTNVLCIGGKIIGSAIALEIVKVWMTTDHLGDVEKYKRRVDKVVEISEKHLKKLSEL
>NZ_CP011114.1|WP_025694813.1|601476_601713_-|helix-turn-helix-transcriptional-regulator
MEYNRYTLHCKLDEILKEHDNMSVLKLSKEIGHRRTTIMELMHNTNMEKKKISAALIVKLCLYFDISPNELFEVRPKE
>NZ_CP011114.1|WP_025695200.1|616193_618635_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRQKDKKIQTVEEHQKEVQVGCEQYGAKIGVTHLAGLAGMLHDIGKNTNEFNTYLVKAVYHPEAASRKGSVDHSTAGGKLLYQRYHKGEGVSMNKLAAEWIGNCIISHHQGLRDFLSPQLDSPYLKRVGQKELDEYDRAVAAFFEQVPADKLDRYFEQAVAELKLALTIIQEYKLPRITLALLIKYIFSCLIDADRTNTRDFEADEHTDWIKDHQSFFLESYNRLLAKIALLNEAKDADHPINRLRREMSRQCEEFALLSSGIYTLSIPTGGGKTLASLRYALRHALETGKERIIYIVPFTTIIEQNAKEIREIIQNDDMVLEHHSNVVDEIDPGSDDYDLEKEKLKLARDHWDRPIIFTTMVQFLNTFYAKGTRNVRRLHQLSNAVLIFDEVQAVPHRCLSLFNAALNFLHTFGKSSIVLCTATQPALDDVRHKLHLSEQSEMIKNLSDVGRYFKRVELVDYTAKCGASGWGAETLASFVRERMNEVNSVLVILNTKTAVRKLFAELDQEEWAEDRKVRLFHLSTNMCAAHRKDVLAELIQVLDSKVNERVICVSTQLIEAGVNISFDCVIRSLSGLDSITQAAGRCNRHGKDPLRQVYVIQSADENLNHLQEIKIGAEMTLKVLDDFRKKPELYENDRLSPSAMKAYFKYYYHRIKDELDYPVPKLGGKKLFNLLSSNKAYYDAYRNRYSEKLGLGSLQALATAEQYFEVIDNPATSVIVPYNAEARDLIANLNGELDIWELGDLLRKAQQYVVNVYKHDLVKLDKSGELFPLLNGNVLALHDTAYSERFGVGTEGDGEWGTSII
>NZ_CP011114.1|WP_025695201.1|619236_619959_+|type-I-C-CRISPR-associated-protein-Cas5
MRNQIEFEVYGKYGLFTDPLTKIGGEKFSYQIPTYQALKGIVESIYWKPTLIWIIDEVRVMEPIQTESKGIRPIEYGGGNTLSYYTYLKEPRYQVRAHFEFNPHREDLIQDRNEHKHHNIAKRAVQAGGRRDIFLGARECQGYVEPCEYGKGVGFYDEIAEIDFGIMVHGINYPDETGRQERETRLWRAKMEHGIIRYIRPEECTLLRKTGEGHIKSFGLADIQSVEELYADYFQGEERG
>NZ_CP011114.1|WP_025695202.1|619955_621905_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTWLADLYKTYENNAHLTGQFERKKNGREYALIPVSHTTQSSHIEVRLDMEGNLLQARVVEKEEASTIIPCTEASASRTSAPVPHPLFDKLVYVAGDYTRYYGEVKGTPHADYMKQLLAWCESPAAHSKVQSVYTYLSRGTLIADLVQREVLWLDEKGQLAPKWTPAMEQRYGEKKAIFKVIASDQSAAFIRFAVHVPGDPEDRLWRDRSVQEAFIRYNEMELAEQELCYVTGEYLPYADKHTSRIRNSGDKTKLISANDSLGFTYRGRFRSGREAAAVSYEVSQKGHNALKWLIDRQGVTIDGKVFLVWGIDNPDLPPPWEDGLDLYGEEEDEDTAGDAAHREFAGQFRRAIHGYRYNTDDYKSEVVIMVLDAATPGRLSIVYYRNLNKELFFNRLNYWHATCRWLHRYRKNEQKEILSFTGAPATRDIAFAAYGPQASDKVVKVLLERMLPCIVDKRPVPQDIVRSAVNRASNPVGMEPWEWEKTLSIACALVKKTYEKEGFTVSLDVENEDRSYLFGRMLAIADVLERRALGKEEKRATNAVRYMNVFAQHPGRTWEIIQSNLQPYQAKMGTKDGIINYCNKMLDEVGSRLKLEDYNDNRLNGRYLLGFYSQRNELYKSREQREAEAGQTARTDESANNDVQGENE
>NZ_CP011114.1|WP_025695203.1|621904_622792_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSTLDHKIDFAVVFSVHNANPNGDPLNGNRPRQNYDGYGEVSDVCIKRKIRNRLQDMGESILVQSDERRGDGYRSIKERVDANAEVQEFAKGKKANNDLYAQAACNAWLDVRSFGQVFAFGGAEGSGSGVSIGVRGPVSIHTAVSIDPIDITSMQITKSVNATTPKDNPNKKSPDTMGMKHRVDFGVYVFYGSINTQLAGKTGFTYEDAEKIREALVTLFENDTSSARPDGSMEVHKVYWWEHKSGLGQYSSAKVHRSLQIHLNEGVTQPKSFDDDYTCTLQPLDGLEVREYAGL
>NZ_CP011114.1|WP_025695204.1|622778_623438_+|CRISPR-associated-protein-Cas4
MPDYNEDDYLLLSGIQHFNFCRRQWALIHVEQQWEENVRTLEGTYVHRIADQPHLREKRGNKLIVRALPVHSGTLGITGICDVVEFVRDPAGIPLSGEEGLYLPYPVEYKRGKPKKNDSDRSQLIAQLMCLEEMLACDLSLGYLYYNETKHRVEVPVTLSDREQVKAVLQEMHHYFAKKHTPKAKAGPHCQSCSLHNVCLPEMLKKRSVASYIESRLSE
>NZ_CP011114.1|WP_025695205.1|623434_624466_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTTPDTYLSLDGENIVIRQEENILGRYPLHNLEAVCTFGYAGVSPALMGSCAERSIGLTFMTRTGRFLARVTGESRGNVVLRKEQYRISDDERRSALVARNFILGKIYNAKWILERATRDYALRLDIPRIKKVSAALSESMNLVHSVEDLDILRGVEGSAAVQYNSVFDELILQQKDDFFFRGRNKRPPLDNVNALLSFAYTLLSNDVRSALESVGLDAYVGFLHRDRPGRASLALDMMEELRGVYADRFVLSLINKKLINPKGFYRKENGAVLMDDDTRKQVIKGWQERKQEKIIHPYLNEKISWGLVPYSQALLLARYIRGDLDEYPPFLWK
>NZ_CP011114.1|WP_025695206.1|624476_624767_+|CRISPR-associated-endonuclease-Cas2
MLVLITYDVSTKSAEGRRRLSQVAKKCLDYGQRVQNSVFECIVDTTQFRRLKFELEELIDEETDSLRFYNLGDKYKTKVEHIGVKSSYDMESPLII
>NZ_CP011114.1|WP_025695207.1|627149_627896_+|DeoR/GlpR-transcriptional-regulator
MLTEERHGMIIQRLQEKGVVKMQELTEMLGASESTVRRDLIDLESRNLLKRVHGGASLLPHKSQELGMEEKTSKNIQQKNSIASLAAAQLLDGECIYLDAGTTTLAMISHIDAKGVTVVTNGLSHIEELVRKQIPSYLLGGMMKSHTKAVVGSIALQNMENFRFDKCFLGTNGVDAKMGYTTPDPEEALIKRRAHQLSGKTYVLADSSKFGEVAFAKLFDLQEAVVITDTVPERLRQSIASKTKIIEG
>NZ_CP011114.1|WP_025695208.1|627899_628811_+|1-phosphofructokinase
MIYTVTLNPSIDYIVEVEDLKLGDLNRMKRDLKLPGGKGINVSRVLDQLGVENTALGFLGGFTGRFIADKLREDSIKSDFVFVADDTRINIKLKHGDETEINGLGPVIRDEEAQQLLDKLSHLQQNDIVILSGSAPPSLGGDFYQKLIRACGQSGAEFVIDTTGKALMNALVHKPLLVKPNHHELAELYGVTINSVDEIITYGRKLLEEGAKHVLISMAGEGALLITEQEVYRATVPSGTVKNSVGAGDSMIAGFVGTLFLTGDPIEAFRAGVASGSATAFSDDLATKEEIERLRPQVQISKL
>NZ_CP011114.1|WP_046722766.1|628874_630848_+|PTS-fructose-transporter-subunit-IIABC
MRITDLMIKQTMIMDLKATTKEAAIDELIASLAANGRINDPVLFKQMILKREEESSTGIGGGIAMPHAKTKAVNEATVVFAKSAGGVDFESLDGEPAHLFFMIAAPEGAANTHLRTLAALSRLLIDVEFIDQLKNTKTPDDVTALFDAKQEEQEAAKKAEEEKTKQEEEAKAKQPAASGMIVGNPSNMEAFVVAVTACPTGIAHTFMAEDALKKKAKEMGINIRVETNGSEGAKNVLTPDEIRRASGVIVAADKQVEMARFDGKPVLQRPVSDGIRKPEELINKAVAGDAPIYRSQGKAASDAAPAGKISVGSKIYKDLMNGISHMLPFVVGGGILLAISFLFEQIASVDNPIVKLLQTIGGGDGAFHFLIPILAGFIAMSIGDRPALMPGIVGGFMAASSNAGFLGGLAAGFLAGYVVIGLRKVFAGIPQTLDGLKPILLYPVFGLLITGAIMYYLFDPFFSWINTGLIDVLNNLGTGNAVLLGLVLGGMMAIDMGGPFNKAAYTFAIGVFTSTGDGAMMAAVMAGGMVPPLAIALATTLFKNKFTEDERKSGITNYVLGLSFITEGAIPFAAADPMRVLTSCILGSAVAGGLTQFWKINIPAPHGGIFVAALANHALLFLLAVAIGAVISALVFGLWKKPLVEKPVEVSAKRSLV

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Crispr_ID: NZ_CP011114_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_7

614690-615734

TypeI

I-C

Consensus_repeat	Method
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCTCCCNATNCGGGAGCGTGGATTGAAAT	CRT
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	PILER-CR

15 spacers

cas3,cas5,cas8c,cas7,cas4,cas1,cas2

The CRISPR arrays of NZ_CP011114_7

>merge|NZ_CP011114|7|614690-615734|CRISPRCasFinder,CRT,PILER-CR
GTCGCTCCCTATACGGGAGCGTGGATTGAAATCATCTATCTCACCGCCTGTATTCTGAATGATGGAGTCGCTCCCTATACGGGAGCGTGGATTGAAATCGCGAGATACCGCTCGCTCCCACCGTTTTCCAGAAGTCGCTCCCTATACGGGAGCGTGGATTGAAATGAAGCATCCATGTGGATTACTTGGGCGACGTAGACAGTCGCTCCCTATACGGGAGCGTGGATTGAAATTGTCTGTAGCGCGTTGTCCACGGCGATAGATCCGGTCGCTCCCTATACGGGAGCGTGGATTGAAATTGAGCATATAAATGGACTCTGCCGGGAGTAGACATGTCGCTCCCTATACGGGAGCGTGGATTGAAATAATTAAGGAGCAAATACATATGAAAACTAAAACAGTCGCTCCCTATACGGGAGCGTGGATTGAAATCGCGATCCATGTTACTTGCACGCCACCATACACACCGTCGCTCCCTATACGGGAGCGTGGATTGAAATCGGAACAACCCCATCTGGCGGTATGATTCCGCAGGGTCGCTCCCTATACGGGAGCGTGGATTGAAATCCCTCGGCACAGTAATTTTTTATTGTTCCAGGTGTCGTCGCTCCCTATACGGGAGCGTGGATTGAAATTGGAAAACCATGACATAATTATTGTCCTCCTTTGTGTCGCTCCCCATGCGGGAGCGTGGATTGAAATGATAAGGAAACAAGTGACACGTTCACGAAAGCCATGCGTCGCTCCCCATGCGGGAGCGTGGATTGAAATCGCCGCCTCACTGTTACGTGCGGCGAGTGCTTCCTGGTCGCTCCCCATGCGGGAGCGTGGATTGAAATTCCGGAGCCACATCGCCGATAATCCGCAGCTCCGGCGGTCGCTCCCCAAGCGGGAGCGTGGATTGAAATCACTGCTCCCCCATGAGGCGCACCTGGTTGGCCCAACTGTCGCTCCCCATGCGGGAGCGTGGATTGAAATGGTTTCGTGGTAGTAAGTTTAGATGGTTATAAAAAGTCGCTTTCCGTGCGAGAACTCGGATTGAAAC

>NZ_CP011114|7|7|614690-615734|CRISPRCasFinder
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CATCTATCTCACCGCCTGTATTCTGAATGATGGA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CGCGAGATACCGCTCGCTCCCACCGTTTTCCAGAA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	GAAGCATCCATGTGGATTACTTGGGCGACGTAGACA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGTCTGTAGCGCGTTGTCCACGGCGATAGATCCG
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGAGCATATAAATGGACTCTGCCGGGAGTAGACAT
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	AATTAAGGAGCAAATACATATGAAAACTAAAACA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CGCGATCCATGTTACTTGCACGCCACCATACACACC
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CGGAACAACCCCATCTGGCGGTATGATTCCGCAGG
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CCCTCGGCACAGTAATTTTTTATTGTTCCAGGTGTC
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGGAAAACCATGACATAATTATTGTCCTCCTTTGT
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	GATAAGGAAACAAGTGACACGTTCACGAAAGCCATGC
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	CGCCGCCTCACTGTTACGTGCGGCGAGTGCTTCCTG
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	TCCGGAGCCACATCGCCGATAATCCGCAGCTCCGGCG
GTCGCTCCCCAAGCGGGAGCGTGGATTGAAAT	CACTGCTCCCCCATGAGGCGCACCTGGTTGGCCCAACT
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	GGTTTCGTGGTAGTAAGTTTAGATGGTTATAAAAA
GTCGCTTTCCGTGCGAGAACTCGGATTGAAAC

>NZ_CP011114|7|7|614690-615734|CRT
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CATCTATCTCACCGCCTGTATTCTGAATGATGGA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CGCGAGATACCGCTCGCTCCCACCGTTTTCCAGAA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	GAAGCATCCATGTGGATTACTTGGGCGACGTAGACA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGTCTGTAGCGCGTTGTCCACGGCGATAGATCCG
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGAGCATATAAATGGACTCTGCCGGGAGTAGACAT
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	AATTAAGGAGCAAATACATATGAAAACTAAAACA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CGCGATCCATGTTACTTGCACGCCACCATACACACC
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CGGAACAACCCCATCTGGCGGTATGATTCCGCAGG
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CCCTCGGCACAGTAATTTTTTATTGTTCCAGGTGTC
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGGAAAACCATGACATAATTATTGTCCTCCTTTGT
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	GATAAGGAAACAAGTGACACGTTCACGAAAGCCATGC
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	CGCCGCCTCACTGTTACGTGCGGCGAGTGCTTCCTG
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	TCCGGAGCCACATCGCCGATAATCCGCAGCTCCGGCG
GTCGCTCCCCAAGCGGGAGCGTGGATTGAAAT	CACTGCTCCCCCATGAGGCGCACCTGGTTGGCCCAACT
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	GGTTTCGTGGTAGTAAGTTTAGATGGTTATAAAAA
GTCGCTTTCCGTGCGAGAACTCGGATTGAAAC

>NZ_CP011114|7|6|614891-615667|PILER-CR
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGTCTGTAGCGCGTTGTCCACGGCGATAGATCCG
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGAGCATATAAATGGACTCTGCCGGGAGTAGACAT
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	AATTAAGGAGCAAATACATATGAAAACTAAAACA
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CGCGATCCATGTTACTTGCACGCCACCATACACACC
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CGGAACAACCCCATCTGGCGGTATGATTCCGCAGG
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	CCCTCGGCACAGTAATTTTTTATTGTTCCAGGTGTC
GTCGCTCCCTATACGGGAGCGTGGATTGAAAT	TGGAAAACCATGACATAATTATTGTCCTCCTTTGT
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	GATAAGGAAACAAGTGACACGTTCACGAAAGCCATGC
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	CGCCGCCTCACTGTTACGTGCGGCGAGTGCTTCCTG
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT	TCCGGAGCCACATCGCCGATAATCCGCAGCTCCGGCG
GTCGCTCCCCAAGCGGGAGCGTGGATTGAAAT	CACTGCTCCCCCATGAGGCGCACCTGGTTGGCCCAACT
GTCGCTCCCCATGCGGGAGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025695207.1\|627149_627896_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP011114.1\|WP_025695208.1\|627899_628811_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|238570
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|225390
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP011114.1\|WP_025695204.1\|622778_623438_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl\|CDD\|223932
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP011114.1\|WP_025695206.1\|624476_624767_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|366864
NZ_CP011114.1\|WP_025695202.1\|619955_621905_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP011114.1\|WP_025695203.1\|621904_622792_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP011114.1\|WP_025695205.1\|623434_624466_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl\|CDD\|376799
NZ_CP011114.1\|WP_046722766.1\|628874_630848_+\|PTS-fructose-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|236740
NZ_CP011114.1\|WP_025695201.1\|619236_619959_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|308978
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025695207.1\|627149_627896_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.48428e-82
NZ_CP011114.1\|WP_025695208.1\|627899_628811_+\|1-phosphofructokinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	7.69617e-137
NZ_CP011114.1\|WP_025694813.1\|601476_601713_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.71168e-06
NZ_CP011114.1\|WP_025694818.1\|606927_608016_+\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	1.90047e-25
NZ_CP011114.1\|WP_025694819.1\|608241_609444_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP011114.1\|WP_025695204.1\|622778_623438_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.03149e-28
NZ_CP011114.1\|WP_175491834.1\|609668_609920_+\|ribbon-helix-helix-protein,-CopG-family	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	2.01583e-17
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	1.19044e-05
NZ_CP011114.1\|WP_025695206.1\|624476_624767_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.3558e-30
NZ_CP011114.1\|WP_025694815.1\|605107_605320_-\|DUF86-domain-containing-protein	gnl\|CDD\|366864	pfam01934, DUF86, Protein of unknown function DUF86. The function of members of this family is unknown.	0.00129737
NZ_CP011114.1\|WP_025695202.1\|619955_621905_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	5.13918e-171
NZ_CP011114.1\|WP_025695203.1\|621904_622792_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.31692e-125
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	4.92745e-41
NZ_CP011114.1\|WP_025695205.1\|623434_624466_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP011114.1\|WP_025694814.1\|604519_604990_+\|ribose-5-phosphate-isomerase-B	gnl\|CDD\|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	2.66566e-62
NZ_CP011114.1\|WP_046722766.1\|628874_630848_+\|PTS-fructose-transporter-subunit-IIABC	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	1.71846e-135
NZ_CP011114.1\|WP_025695201.1\|619236_619959_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	2.36826e-92
NZ_CP011114.1\|WP_025694817.1\|606115_606577_+\|hypothetical-protein	gnl\|CDD\|308978	pfam03682, UPF0158, Uncharacterized protein family (UPF0158).	2.63302e-07
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.76854e-66
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0

>NZ_CP011114.1|WP_025695199.1|612813_613785_-|S-layer-homology-domain-containing-protein
MMKRQTFRHNAKKMTIACGILAGAVLFGASAFAFSDLKGDPAEAKINALHEAGVINGVTSQLFAPKSKMTYGQAVQLIVSGLALKTNPVPGSPSKASDYFAKVDDKSWYAPSLLIAVQNGLPLDKAVNPNAAVSRATFAQLLDAALKAKGDFPVTEMYFNIADGGKLSAEVNGSLQTLLNMRIISLDPGGKFRPNDAVTRSEAAAWVHDARAFVQSMFGGDGSADTSQGADINVEKAADGVNKVSVTVGNLPNPGYGLTIAKIEFGEGKKAVIYYEVTKPGPGMYPQVISKATAVAYLPEGYVASAKPMPGSYTPPEPDSPQF
>NZ_CP011114.1|WP_025694820.1|610476_612666_+|RNA-binding-transcriptional-accessory-protein
MNIVSDEAARRERQMMIGQIAKELGLSERQVGTTAGLLDEGNTIPFIARYRKEMTGELDENALRDIEERLSYLRSLGERKREVIRIIEEQGKLTDELREQIAGAVKLQEVEDLYRPYRQKRKTRASVAKEKGLGPLADWIMEQRRGGNPEAEAGKYVDPAKGVESAEQALQGAQDIIAEAIADDAAVRSWVRQFTASQGILVSEAKDKEQESVYENYYSYREPVHKMPPHRILAINRGERENVLKVSIEVDAARIHAHITRKLVKGPSPVKELLEAVAEDAYKRLIAPSVEREVRGEMTEKGENQAISIFSGNLRSLLLQPPVKGRRVLGVDPAYRTGCKLAVVDETGKLLEVAVTYPTPPHNKKREAAEKFKELIAKYGIQLIVIGNGTGSRETEQFTAETIAEIGDPGLAYLIVNEAGASVYSASKLAQEEFPDLDVAERSAASIARRVQDPLAELVKIEPKAIGVGQYQHDVSQKHLDESLTAVVESAVNHVGVDVNTASPSLLSYVAGINSTIAKNIVKFREENGSFKNRKQLQKVPRLGAKSYEQCIGFLRIPEGENTLDRTPIHPESYDVVSRLFKELGLALSQIGSKELAAELAAQNPEELAARLDVGVPTLRDILESLQRPGRDPREELPPPIFRTDVLKIEDLAPGMELQGTVRNVIDFGAFVDIGIKNDGLVHISQLSSSFVKHPMDVVSVGDNVTVWVLSVDLKKGRVSLTMRPPRGE
>NZ_CP011114.1|WP_025691534.1|609923_610274_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDASSHGFDRDSVILLEQVRTIDKQRLTDKITHLDDETMKKVDDSLQISLGLIDF
>NZ_CP011114.1|WP_175491834.1|609668_609920_+|ribbon-helix-helix-protein,-CopG-family
MISLPDHLLQEVDGIVQMENSNRSELIRQAMKLYLSERRKRSIRESMQRGYMEMAKINLTMACEAFLAEEDADSTLGRLVSGV
>NZ_CP011114.1|WP_025694819.1|608241_609444_+|alanine-racemase
MQESYRPTVAEIDLDALRANYESFRRHLPAGVKFMACVKGNAYGHGAVEVTRELERLGADYVSVAFLDEAIELRQAGIVLPILVLGYTPPEAIAAAWENDVTVTLFTPEGLEAASKLPLNDSRKLKVHIKIDSGMGRLGLLPDDVPLFIEEAQRVRQIELEGMFTHFAKADEADKSYTLEQYRRFMGVTEALRERQIHIPIIHTGNSATAIDTPHLSPNMVRVGVSIYGFYPSTEVNRQQVKLHPVMTLKTKAVYVKSLPESWGVSYGTRYRADNGEYIATLPIGYADGYSRMLSGKAEVLIRGRRVPVVGTICMDQCMVSLKSFANEAEQIKAGEEVVLIGRQAGVSITADELALLLGTIHYEVTCMLAHRVPRVYIREGSAPRLVNALLQAPSPNPVS
>NZ_CP011114.1|WP_025694818.1|606927_608016_+|outer-membrane-lipoprotein-carrier-protein-LolA
MRRIAWVLAIIMSVTLIMTGCGKKDSASVVKDLNDVADKLESKTGAYQGEGTMTLYTGEQPQEYRVEVWYKNPSYYRISLANVQKNITQIVLRNDEGVFVLTPSLGKSFRFQSDWPDKQGQVYLYQTLVKGIVADNNRQFVADKDSYVFEVAANYQSSALVRQKIWLDKKTYAPKQVQVSDSEAKVVVDVKFNKFAFNPEFSADSFDMQKNMASGGNSKNTVAQVDENGNPLPAADNQEGTQAQANAALGDFGIIEPGYTPEGVTFKDSNKVENSDNHAVLLRYDGIYQYTIMESRPLDQAVSLAPGTLIDLGFTAGLLTGDEQQTLTWMSGDGVEFRITSANLPPSEMMEIAASMQDQTGK
>NZ_CP011114.1|WP_025694817.1|606115_606577_+|hypothetical-protein
MDKLTLTEAQLREIVDSYDMQHEGIDSFFNLESKEVVFVNNEFSDPEDEELEEEIEEGFGEIWFRLPERYSSDGYRDMEDFVDIVSDERLRELLITSLRGGRGFFRRFKDTLGDNPEELERYYQFVYERNRERVLKWMEAEFDLEIEIIGGED
>NZ_CP011114.1|WP_025694815.1|605107_605320_-|DUF86-domain-containing-protein
MNRDILLNKTENIRICIIFNLQRCCEACIELAMHSVSELKLGVSQSSRDAFEMLYNKGIIDEKLKEYMSR
>NZ_CP011114.1|WP_025694814.1|604519_604990_+|ribose-5-phosphate-isomerase-B
MKIAVAGDHAGFSLKEEVKALLTSQGHEVVDFGTHSEEASDLPDYIYPAALAVAEGKADRGIFIDGVGYGSAMIANKIYGVYAAVCQDPFCAELARSHSDTNVLCIGGKIIGSAIALEIVKVWMTTDHLGDVEKYKRRVDKVVEISEKHLKKLSEL
>NZ_CP011114.1|WP_025694813.1|601476_601713_-|helix-turn-helix-transcriptional-regulator
MEYNRYTLHCKLDEILKEHDNMSVLKLSKEIGHRRTTIMELMHNTNMEKKKISAALIVKLCLYFDISPNELFEVRPKE
>NZ_CP011114.1|WP_025695200.1|616193_618635_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRQKDKKIQTVEEHQKEVQVGCEQYGAKIGVTHLAGLAGMLHDIGKNTNEFNTYLVKAVYHPEAASRKGSVDHSTAGGKLLYQRYHKGEGVSMNKLAAEWIGNCIISHHQGLRDFLSPQLDSPYLKRVGQKELDEYDRAVAAFFEQVPADKLDRYFEQAVAELKLALTIIQEYKLPRITLALLIKYIFSCLIDADRTNTRDFEADEHTDWIKDHQSFFLESYNRLLAKIALLNEAKDADHPINRLRREMSRQCEEFALLSSGIYTLSIPTGGGKTLASLRYALRHALETGKERIIYIVPFTTIIEQNAKEIREIIQNDDMVLEHHSNVVDEIDPGSDDYDLEKEKLKLARDHWDRPIIFTTMVQFLNTFYAKGTRNVRRLHQLSNAVLIFDEVQAVPHRCLSLFNAALNFLHTFGKSSIVLCTATQPALDDVRHKLHLSEQSEMIKNLSDVGRYFKRVELVDYTAKCGASGWGAETLASFVRERMNEVNSVLVILNTKTAVRKLFAELDQEEWAEDRKVRLFHLSTNMCAAHRKDVLAELIQVLDSKVNERVICVSTQLIEAGVNISFDCVIRSLSGLDSITQAAGRCNRHGKDPLRQVYVIQSADENLNHLQEIKIGAEMTLKVLDDFRKKPELYENDRLSPSAMKAYFKYYYHRIKDELDYPVPKLGGKKLFNLLSSNKAYYDAYRNRYSEKLGLGSLQALATAEQYFEVIDNPATSVIVPYNAEARDLIANLNGELDIWELGDLLRKAQQYVVNVYKHDLVKLDKSGELFPLLNGNVLALHDTAYSERFGVGTEGDGEWGTSII
>NZ_CP011114.1|WP_025695201.1|619236_619959_+|type-I-C-CRISPR-associated-protein-Cas5
MRNQIEFEVYGKYGLFTDPLTKIGGEKFSYQIPTYQALKGIVESIYWKPTLIWIIDEVRVMEPIQTESKGIRPIEYGGGNTLSYYTYLKEPRYQVRAHFEFNPHREDLIQDRNEHKHHNIAKRAVQAGGRRDIFLGARECQGYVEPCEYGKGVGFYDEIAEIDFGIMVHGINYPDETGRQERETRLWRAKMEHGIIRYIRPEECTLLRKTGEGHIKSFGLADIQSVEELYADYFQGEERG
>NZ_CP011114.1|WP_025695202.1|619955_621905_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTWLADLYKTYENNAHLTGQFERKKNGREYALIPVSHTTQSSHIEVRLDMEGNLLQARVVEKEEASTIIPCTEASASRTSAPVPHPLFDKLVYVAGDYTRYYGEVKGTPHADYMKQLLAWCESPAAHSKVQSVYTYLSRGTLIADLVQREVLWLDEKGQLAPKWTPAMEQRYGEKKAIFKVIASDQSAAFIRFAVHVPGDPEDRLWRDRSVQEAFIRYNEMELAEQELCYVTGEYLPYADKHTSRIRNSGDKTKLISANDSLGFTYRGRFRSGREAAAVSYEVSQKGHNALKWLIDRQGVTIDGKVFLVWGIDNPDLPPPWEDGLDLYGEEEDEDTAGDAAHREFAGQFRRAIHGYRYNTDDYKSEVVIMVLDAATPGRLSIVYYRNLNKELFFNRLNYWHATCRWLHRYRKNEQKEILSFTGAPATRDIAFAAYGPQASDKVVKVLLERMLPCIVDKRPVPQDIVRSAVNRASNPVGMEPWEWEKTLSIACALVKKTYEKEGFTVSLDVENEDRSYLFGRMLAIADVLERRALGKEEKRATNAVRYMNVFAQHPGRTWEIIQSNLQPYQAKMGTKDGIINYCNKMLDEVGSRLKLEDYNDNRLNGRYLLGFYSQRNELYKSREQREAEAGQTARTDESANNDVQGENE
>NZ_CP011114.1|WP_025695203.1|621904_622792_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSTLDHKIDFAVVFSVHNANPNGDPLNGNRPRQNYDGYGEVSDVCIKRKIRNRLQDMGESILVQSDERRGDGYRSIKERVDANAEVQEFAKGKKANNDLYAQAACNAWLDVRSFGQVFAFGGAEGSGSGVSIGVRGPVSIHTAVSIDPIDITSMQITKSVNATTPKDNPNKKSPDTMGMKHRVDFGVYVFYGSINTQLAGKTGFTYEDAEKIREALVTLFENDTSSARPDGSMEVHKVYWWEHKSGLGQYSSAKVHRSLQIHLNEGVTQPKSFDDDYTCTLQPLDGLEVREYAGL
>NZ_CP011114.1|WP_025695204.1|622778_623438_+|CRISPR-associated-protein-Cas4
MPDYNEDDYLLLSGIQHFNFCRRQWALIHVEQQWEENVRTLEGTYVHRIADQPHLREKRGNKLIVRALPVHSGTLGITGICDVVEFVRDPAGIPLSGEEGLYLPYPVEYKRGKPKKNDSDRSQLIAQLMCLEEMLACDLSLGYLYYNETKHRVEVPVTLSDREQVKAVLQEMHHYFAKKHTPKAKAGPHCQSCSLHNVCLPEMLKKRSVASYIESRLSE
>NZ_CP011114.1|WP_025695205.1|623434_624466_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTTPDTYLSLDGENIVIRQEENILGRYPLHNLEAVCTFGYAGVSPALMGSCAERSIGLTFMTRTGRFLARVTGESRGNVVLRKEQYRISDDERRSALVARNFILGKIYNAKWILERATRDYALRLDIPRIKKVSAALSESMNLVHSVEDLDILRGVEGSAAVQYNSVFDELILQQKDDFFFRGRNKRPPLDNVNALLSFAYTLLSNDVRSALESVGLDAYVGFLHRDRPGRASLALDMMEELRGVYADRFVLSLINKKLINPKGFYRKENGAVLMDDDTRKQVIKGWQERKQEKIIHPYLNEKISWGLVPYSQALLLARYIRGDLDEYPPFLWK
>NZ_CP011114.1|WP_025695206.1|624476_624767_+|CRISPR-associated-endonuclease-Cas2
MLVLITYDVSTKSAEGRRRLSQVAKKCLDYGQRVQNSVFECIVDTTQFRRLKFELEELIDEETDSLRFYNLGDKYKTKVEHIGVKSSYDMESPLII
>NZ_CP011114.1|WP_025695207.1|627149_627896_+|DeoR/GlpR-transcriptional-regulator
MLTEERHGMIIQRLQEKGVVKMQELTEMLGASESTVRRDLIDLESRNLLKRVHGGASLLPHKSQELGMEEKTSKNIQQKNSIASLAAAQLLDGECIYLDAGTTTLAMISHIDAKGVTVVTNGLSHIEELVRKQIPSYLLGGMMKSHTKAVVGSIALQNMENFRFDKCFLGTNGVDAKMGYTTPDPEEALIKRRAHQLSGKTYVLADSSKFGEVAFAKLFDLQEAVVITDTVPERLRQSIASKTKIIEG
>NZ_CP011114.1|WP_025695208.1|627899_628811_+|1-phosphofructokinase
MIYTVTLNPSIDYIVEVEDLKLGDLNRMKRDLKLPGGKGINVSRVLDQLGVENTALGFLGGFTGRFIADKLREDSIKSDFVFVADDTRINIKLKHGDETEINGLGPVIRDEEAQQLLDKLSHLQQNDIVILSGSAPPSLGGDFYQKLIRACGQSGAEFVIDTTGKALMNALVHKPLLVKPNHHELAELYGVTINSVDEIITYGRKLLEEGAKHVLISMAGEGALLITEQEVYRATVPSGTVKNSVGAGDSMIAGFVGTLFLTGDPIEAFRAGVASGSATAFSDDLATKEEIERLRPQVQISKL
>NZ_CP011114.1|WP_046722766.1|628874_630848_+|PTS-fructose-transporter-subunit-IIABC
MRITDLMIKQTMIMDLKATTKEAAIDELIASLAANGRINDPVLFKQMILKREEESSTGIGGGIAMPHAKTKAVNEATVVFAKSAGGVDFESLDGEPAHLFFMIAAPEGAANTHLRTLAALSRLLIDVEFIDQLKNTKTPDDVTALFDAKQEEQEAAKKAEEEKTKQEEEAKAKQPAASGMIVGNPSNMEAFVVAVTACPTGIAHTFMAEDALKKKAKEMGINIRVETNGSEGAKNVLTPDEIRRASGVIVAADKQVEMARFDGKPVLQRPVSDGIRKPEELINKAVAGDAPIYRSQGKAASDAAPAGKISVGSKIYKDLMNGISHMLPFVVGGGILLAISFLFEQIASVDNPIVKLLQTIGGGDGAFHFLIPILAGFIAMSIGDRPALMPGIVGGFMAASSNAGFLGGLAAGFLAGYVVIGLRKVFAGIPQTLDGLKPILLYPVFGLLITGAIMYYLFDPFFSWINTGLIDVLNNLGTGNAVLLGLVLGGMMAIDMGGPFNKAAYTFAIGVFTSTGDGAMMAAVMAGGMVPPLAIALATTLFKNKFTEDERKSGITNYVLGLSFITEGAIPFAAADPMRVLTSCILGSAVAGGLTQFWKINIPAPHGGIFVAALANHALLFLLAVAIGAVISALVFGLWKKPLVEKPVEVSAKRSLV

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Crispr_ID: NZ_CP011114_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_8

624950-626849

TypeI

I-C

Consensus_repeat	Method
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	PILER-CR
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CRT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	PILER-CR

28 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP011114_8

>merge|NZ_CP011114|8|624950-626849|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTCGCACCCCATGCGGGTGCGTGGATTGAAATATCCTCGACTTGTTGGTTTTTTACATTTTTTTGAGTCGCACCCCATGCGGGTGCGTGGATTGAAATAAGGAAGAGTTGGAACTCCGGGCAAGGGCGCTGGCTGTCGCACCCCATGCGGGTGCGTGGATTGAAATCATTTCTGCTTTTGCCGCTTCGCGTACCAGCCTGGTCGCACCCCATGCGGGTGCGTGGATTGAAATACTAGATAAAGCGGATAGGAACGGATCAGCTCAAGTCGCACCCCATGCGGGTGCGTGGATTGAAATCTGCTGGTACTTCTTGACGCCTTCCGGGTATTGTCGCACCCCATGCGGGTGCGTGGATTGAAATTATTACAATGACATCCTTGTAAATGTTATTTTCGTCGCACCCCATGCGGGTGCGTGGATTGAAATTGTAGTAGTCGGCAGGTTGCAGAGGAATTCGAAAGTCGCACCCCATGCGGGTGCGTGGATTGAAATATGCCTGACCGCTTCCCGATAGCGTAGATTATAGTCGCACCCCATGCGGGTGCGTGGATTGAAATATATCCTCCTTTTGCTTGTGATAAGGTTTTCTTTGTCGCACCCCATGCGGGTGCGTGGATTGAAATCCGATAGCGTAGATTATATAAATCAAGAGCGCGTCGTCGCACCCCATGCGGGTGCGTGGATTGAAATCAGCATCGATGTTCGCCCGTGCTCTCTGGAGTGCGTCGCACCCCATGCGGGTGCGTGGATTGAAATTCATTATTACTGTACGCTGGTCATCACTAAGCAGTCGCACCCCATGCGGGTGCGTGGATTGAAATTGCGTCTGTGAGGATGGATAAGGATTCGGCGTTGTGTCGCACCCCATGCGGGTGCGTGGATTGAAATGCGGAAAGTATCCTCCACCGGACTTTACGATTAGTCGCACCCCATGCGGGTGCGTGGATTGAAATCCGTATGAGACGATATGATCTGGCGTGATCGTTCCTCGTCGCACCCCATGCGGGTGCGTGGATTGAAATCTCGATGTTATAGGACTTTCCGGGAAATTCCGGGAATGTCGCACCCCATGCGGGTGCGTGGATTGAAATTAGACGATCAGGAGTGGGAGCTGATATTCCGGGCGGTCGCACCCCATGCGGGTGCGTGGATTGAAATTTTAATCTCGCTCTACCTTATGTAGACAAGCGAGTCGCACCCCATGCGGGTGCGTGGATTGAAATCACACTCGGCAGTCCCGAGTATCTAAGGAAATGTCTAGTCGCACCCCATGCGGGTGCGTGGATTGAAATCAAAATGTCTTGCACAGAAACGCCCAAGTACCCACGTCGCACCCCATGCGGGTGCGTGGATTGAAATATTCAAAACACTCAGCGGATCGCCGTCTGAGGTGTAGTCGCACCCCATGCGGGTGCGTGGATTGAAATGTTGAAGATGTACGCCAGCAGAGCCGCTTCGCCATTGGTCGCACCCCATGCGGGTGCGTGGATTGAAATGCCCGGCGTCAAGCCTCTGCGCGCTGGACAACTTGTCGCACCCCATGCGGGTGCGTGGATTGAAATTCCCTGAACCGATGAAGGGTTATATACCGGCTGAGTCGCACCCCATGTGGGTGCGTGGATTGAAATAGTACCGGGATGAAATATAAACTGTCCCGGCTGAGTCGCACCCCATGTGGGTGCGTGGATTGAAATCCCGTAATGATCGACAATGTAGGACAGCAATTGTACGGTCGCACCCCATGTGGGTGCGTGGATTGAAATCAGAGCCGCCGACAAAGGAGGAAATAAAAGATGATACGTCGCTCCCCATGCGGGTGCGTGGATTGAAATTTATACTGTACCAGATCAACCAAACACTCAAACACGTCGCACCCCATGTGGGTGCGTGGATTGAAAT

>NZ_CP011114|8|7|624950-625640|PILER-CR
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATCCTCGACTTGTTGGTTTTTTACATTTTTTTGA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	AAGGAAGAGTTGGAACTCCGGGCAAGGGCGCTGGCT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CATTTCTGCTTTTGCCGCTTCGCGTACCAGCCTG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ACTAGATAAAGCGGATAGGAACGGATCAGCTCAA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CTGCTGGTACTTCTTGACGCCTTCCGGGTATT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TATTACAATGACATCCTTGTAAATGTTATTTTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TGTAGTAGTCGGCAGGTTGCAGAGGAATTCGAAA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATGCCTGACCGCTTCCCGATAGCGTAGATTATA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATATCCTCCTTTTGCTTGTGATAAGGTTTTCTTT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CCGATAGCGTAGATTATATAAATCAAGAGCGCGTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAATCAGCATCGATGTTCGCCCGTGCTCTCTGGAGTGCGTCGCACCCCATGCGGGTGCGTGGATTGAAATTCATTATTACTGTACGCTGGTCATCACTAAGCAGTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TGCGTCTGTGAGGATGGATAAGGATTCGGCGTTGT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GCGGAAAGTATCCTCCACCGGACTTTACGATTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CCGTATGAGACGATATGATCTGGCGTGATCGTTCCTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CTCGATGTTATAGGACTTTCCGGGAAATTCCGGGAAT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TAGACGATCAGGAGTGGGAGCTGATATTCCGGGCG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TTTAATCTCGCTCTACCTTATGTAGACAAGCGA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CACACTCGGCAGTCCCGAGTATCTAAGGAAATGTCTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CAAAATGTCTTGCACAGAAACGCCCAAGTACCCAC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATTCAAAACACTCAGCGGATCGCCGTCTGAGGTGTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GTTGAAGATGTACGCCAGCAGAGCCGCTTCGCCATTG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GCCCGGCGTCAAGCCTCTGCGCGCTGGACAACTT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TCCCTGAACCGATGAAGGGTTATATACCGGCTGA
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	AGTACCGGGATGAAATATAAACTGTCCCGGCTGA
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	CCCGTAATGATCGACAATGTAGGACAGCAATTGTACG
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	CAGAGCCGCCGACAAAGGAGGAAATAAAAGATGATAC
GTCGCTCCCCATGCGGGTGCGTGGATTGAAAT	TTATACTGTACCAGATCAACCAAACACTCAAACAC


>NZ_CP011114|8|8|624950-626849|CRISPRCasFinder
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATCCTCGACTTGTTGGTTTTTTACATTTTTTTGA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	AAGGAAGAGTTGGAACTCCGGGCAAGGGCGCTGGCT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CATTTCTGCTTTTGCCGCTTCGCGTACCAGCCTG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ACTAGATAAAGCGGATAGGAACGGATCAGCTCAA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CTGCTGGTACTTCTTGACGCCTTCCGGGTATT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TATTACAATGACATCCTTGTAAATGTTATTTTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TGTAGTAGTCGGCAGGTTGCAGAGGAATTCGAAA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATGCCTGACCGCTTCCCGATAGCGTAGATTATA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATATCCTCCTTTTGCTTGTGATAAGGTTTTCTTT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CCGATAGCGTAGATTATATAAATCAAGAGCGCGTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CAGCATCGATGTTCGCCCGTGCTCTCTGGAGTGC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TCATTATTACTGTACGCTGGTCATCACTAAGCA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TGCGTCTGTGAGGATGGATAAGGATTCGGCGTTGT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GCGGAAAGTATCCTCCACCGGACTTTACGATTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CCGTATGAGACGATATGATCTGGCGTGATCGTTCCTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CTCGATGTTATAGGACTTTCCGGGAAATTCCGGGAAT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TAGACGATCAGGAGTGGGAGCTGATATTCCGGGCG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TTTAATCTCGCTCTACCTTATGTAGACAAGCGA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CACACTCGGCAGTCCCGAGTATCTAAGGAAATGTCTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CAAAATGTCTTGCACAGAAACGCCCAAGTACCCAC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATTCAAAACACTCAGCGGATCGCCGTCTGAGGTGTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GTTGAAGATGTACGCCAGCAGAGCCGCTTCGCCATTG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GCCCGGCGTCAAGCCTCTGCGCGCTGGACAACTT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TCCCTGAACCGATGAAGGGTTATATACCGGCTGA
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	AGTACCGGGATGAAATATAAACTGTCCCGGCTGA
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	CCCGTAATGATCGACAATGTAGGACAGCAATTGTACG
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	CAGAGCCGCCGACAAAGGAGGAAATAAAAGATGATAC
GTCGCTCCCCATGCGGGTGCGTGGATTGAAAT	TTATACTGTACCAGATCAACCAAACACTCAAACAC
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT

>NZ_CP011114|8|8|624950-626849|CRT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATCCTCGACTTGTTGGTTTTTTACATTTTTTTGA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	AAGGAAGAGTTGGAACTCCGGGCAAGGGCGCTGGCT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CATTTCTGCTTTTGCCGCTTCGCGTACCAGCCTG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ACTAGATAAAGCGGATAGGAACGGATCAGCTCAA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CTGCTGGTACTTCTTGACGCCTTCCGGGTATT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TATTACAATGACATCCTTGTAAATGTTATTTTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TGTAGTAGTCGGCAGGTTGCAGAGGAATTCGAAA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATGCCTGACCGCTTCCCGATAGCGTAGATTATA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATATCCTCCTTTTGCTTGTGATAAGGTTTTCTTT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CCGATAGCGTAGATTATATAAATCAAGAGCGCGTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CAGCATCGATGTTCGCCCGTGCTCTCTGGAGTGC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TCATTATTACTGTACGCTGGTCATCACTAAGCA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TGCGTCTGTGAGGATGGATAAGGATTCGGCGTTGT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GCGGAAAGTATCCTCCACCGGACTTTACGATTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CCGTATGAGACGATATGATCTGGCGTGATCGTTCCTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CTCGATGTTATAGGACTTTCCGGGAAATTCCGGGAAT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TAGACGATCAGGAGTGGGAGCTGATATTCCGGGCG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TTTAATCTCGCTCTACCTTATGTAGACAAGCGA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CACACTCGGCAGTCCCGAGTATCTAAGGAAATGTCTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CAAAATGTCTTGCACAGAAACGCCCAAGTACCCAC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATTCAAAACACTCAGCGGATCGCCGTCTGAGGTGTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GTTGAAGATGTACGCCAGCAGAGCCGCTTCGCCATTG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GCCCGGCGTCAAGCCTCTGCGCGCTGGACAACTT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TCCCTGAACCGATGAAGGGTTATATACCGGCTGA
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	AGTACCGGGATGAAATATAAACTGTCCCGGCTGA
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	CCCGTAATGATCGACAATGTAGGACAGCAATTGTACG
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	CAGAGCCGCCGACAAAGGAGGAAATAAAAGATGATAC
GTCGCTCCCCATGCGGGTGCGTGGATTGAAAT	TTATACTGTACCAGATCAACCAAACACTCAAACAC
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT

>NZ_CP011114|8|8|625740-626849|PILER-CR
	ATCCTCGACTTGTTGGTTTTTTACATTTTTTTGA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	AAGGAAGAGTTGGAACTCCGGGCAAGGGCGCTGGCT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CATTTCTGCTTTTGCCGCTTCGCGTACCAGCCTG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ACTAGATAAAGCGGATAGGAACGGATCAGCTCAA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CTGCTGGTACTTCTTGACGCCTTCCGGGTATT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TATTACAATGACATCCTTGTAAATGTTATTTTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TGTAGTAGTCGGCAGGTTGCAGAGGAATTCGAAA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATGCCTGACCGCTTCCCGATAGCGTAGATTATA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATATCCTCCTTTTGCTTGTGATAAGGTTTTCTTT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CCGATAGCGTAGATTATATAAATCAAGAGCGCGTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAATCAGCATCGATGTTCGCCCGTGCTCTCTGGAGTGCGTCGCACCCCATGCGGGTGCGTGGATTGAAATTCATTATTACTGTACGCTGGTCATCACTAAGCAGTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TGCGTCTGTGAGGATGGATAAGGATTCGGCGTTGT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GCGGAAAGTATCCTCCACCGGACTTTACGATTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CCGTATGAGACGATATGATCTGGCGTGATCGTTCCTC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CTCGATGTTATAGGACTTTCCGGGAAATTCCGGGAAT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TAGACGATCAGGAGTGGGAGCTGATATTCCGGGCG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TTTAATCTCGCTCTACCTTATGTAGACAAGCGA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CACACTCGGCAGTCCCGAGTATCTAAGGAAATGTCTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	CAAAATGTCTTGCACAGAAACGCCCAAGTACCCAC
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	ATTCAAAACACTCAGCGGATCGCCGTCTGAGGTGTA
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GTTGAAGATGTACGCCAGCAGAGCCGCTTCGCCATTG
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	GCCCGGCGTCAAGCCTCTGCGCGCTGGACAACTT
GTCGCACCCCATGCGGGTGCGTGGATTGAAAT	TCCCTGAACCGATGAAGGGTTATATACCGGCTGA
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	AGTACCGGGATGAAATATAAACTGTCCCGGCTGA
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	CCCGTAATGATCGACAATGTAGGACAGCAATTGTACG
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT	CAGAGCCGCCGACAAAGGAGGAAATAAAAGATGATAC
GTCGCTCCCCATGCGGGTGCGTGGATTGAAAT	TTATACTGTACCAGATCAACCAAACACTCAAACAC
GTCGCACCCCATGTGGGTGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025695207.1\|627149_627896_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP011114.1\|WP_025695208.1\|627899_628811_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|238570
NZ_CP011114.1\|WP_025695206.1\|624476_624767_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP011114.1\|WP_025695204.1\|622778_623438_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP011114.1\|WP_046722766.1\|628874_630848_+\|PTS-fructose-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|236740
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP011114.1\|WP_025700354.1\|634028_634457_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|214628
NZ_CP011114.1\|WP_025700349.1\|631658_632153_+\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NZ_CP011114.1\|WP_025695202.1\|619955_621905_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP011114.1\|WP_025695203.1\|621904_622792_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP011114.1\|WP_025700353.1\|633396_633885_+\|SprT-family-protein	unknown	unknown	gnl\|CDD\|235290
NZ_CP011114.1\|WP_025695205.1\|623434_624466_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP011114.1\|WP_155986987.1\|632335_632503_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025695201.1\|619236_619959_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP011114.1\|WP_025700351.1\|632908_633268_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025700347.1\|630959_631511_-\|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|378696
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NZ_CP011114.1\|WP_090834029.1\|632640_632757_-\|cortex-morphogenetic-protein-CmpA	unknown	unknown	gnl\|CDD\|380221

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025695207.1\|627149_627896_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.48428e-82
NZ_CP011114.1\|WP_025695208.1\|627899_628811_+\|1-phosphofructokinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	7.69617e-137
NZ_CP011114.1\|WP_025695206.1\|624476_624767_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.3558e-30
NZ_CP011114.1\|WP_025695204.1\|622778_623438_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.03149e-28
NZ_CP011114.1\|WP_046722766.1\|628874_630848_+\|PTS-fructose-transporter-subunit-IIABC	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	1.71846e-135
NZ_CP011114.1\|WP_025695199.1\|612813_613785_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	1.19044e-05
NZ_CP011114.1\|WP_025700354.1\|634028_634457_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	8.73107e-31
NZ_CP011114.1\|WP_025700349.1\|631658_632153_+\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	4.60321e-09
NZ_CP011114.1\|WP_025695202.1\|619955_621905_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	5.13918e-171
NZ_CP011114.1\|WP_025695203.1\|621904_622792_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.31692e-125
NZ_CP011114.1\|WP_025691534.1\|609923_610274_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	4.92745e-41
NZ_CP011114.1\|WP_025700353.1\|633396_633885_+\|SprT-family-protein	gnl\|CDD\|235290	PRK04351, PRK04351, SprT family protein.	8.32662e-79
NZ_CP011114.1\|WP_025695205.1\|623434_624466_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP011114.1\|WP_090834029.1\|632640_632757_-\|cortex-morphogenetic-protein-CmpA	gnl\|CDD\|380221	NF033225, spore_CmpA, cortex morphogenetic protein CmpA. Members of this family are CmpA (cortex morphogenetic protein A), a small protein (37 amino acids) involved in endospore formation and frequently missed during genome annotation.	1.52728e-15
NZ_CP011114.1\|WP_025695201.1\|619236_619959_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	2.36826e-92
NZ_CP011114.1\|WP_025700347.1\|630959_631511_-\|CGNR-zinc-finger-domain-containing-protein	gnl\|CDD\|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	1.91044e-18
NZ_CP011114.1\|WP_025695200.1\|616193_618635_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.76854e-66
NZ_CP011114.1\|WP_025694820.1\|610476_612666_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0

>NZ_CP011114.1|WP_025695206.1|624476_624767_+|CRISPR-associated-endonuclease-Cas2
MLVLITYDVSTKSAEGRRRLSQVAKKCLDYGQRVQNSVFECIVDTTQFRRLKFELEELIDEETDSLRFYNLGDKYKTKVEHIGVKSSYDMESPLII
>NZ_CP011114.1|WP_025695205.1|623434_624466_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTTPDTYLSLDGENIVIRQEENILGRYPLHNLEAVCTFGYAGVSPALMGSCAERSIGLTFMTRTGRFLARVTGESRGNVVLRKEQYRISDDERRSALVARNFILGKIYNAKWILERATRDYALRLDIPRIKKVSAALSESMNLVHSVEDLDILRGVEGSAAVQYNSVFDELILQQKDDFFFRGRNKRPPLDNVNALLSFAYTLLSNDVRSALESVGLDAYVGFLHRDRPGRASLALDMMEELRGVYADRFVLSLINKKLINPKGFYRKENGAVLMDDDTRKQVIKGWQERKQEKIIHPYLNEKISWGLVPYSQALLLARYIRGDLDEYPPFLWK
>NZ_CP011114.1|WP_025695204.1|622778_623438_+|CRISPR-associated-protein-Cas4
MPDYNEDDYLLLSGIQHFNFCRRQWALIHVEQQWEENVRTLEGTYVHRIADQPHLREKRGNKLIVRALPVHSGTLGITGICDVVEFVRDPAGIPLSGEEGLYLPYPVEYKRGKPKKNDSDRSQLIAQLMCLEEMLACDLSLGYLYYNETKHRVEVPVTLSDREQVKAVLQEMHHYFAKKHTPKAKAGPHCQSCSLHNVCLPEMLKKRSVASYIESRLSE
>NZ_CP011114.1|WP_025695203.1|621904_622792_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSTLDHKIDFAVVFSVHNANPNGDPLNGNRPRQNYDGYGEVSDVCIKRKIRNRLQDMGESILVQSDERRGDGYRSIKERVDANAEVQEFAKGKKANNDLYAQAACNAWLDVRSFGQVFAFGGAEGSGSGVSIGVRGPVSIHTAVSIDPIDITSMQITKSVNATTPKDNPNKKSPDTMGMKHRVDFGVYVFYGSINTQLAGKTGFTYEDAEKIREALVTLFENDTSSARPDGSMEVHKVYWWEHKSGLGQYSSAKVHRSLQIHLNEGVTQPKSFDDDYTCTLQPLDGLEVREYAGL
>NZ_CP011114.1|WP_025695202.1|619955_621905_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTWLADLYKTYENNAHLTGQFERKKNGREYALIPVSHTTQSSHIEVRLDMEGNLLQARVVEKEEASTIIPCTEASASRTSAPVPHPLFDKLVYVAGDYTRYYGEVKGTPHADYMKQLLAWCESPAAHSKVQSVYTYLSRGTLIADLVQREVLWLDEKGQLAPKWTPAMEQRYGEKKAIFKVIASDQSAAFIRFAVHVPGDPEDRLWRDRSVQEAFIRYNEMELAEQELCYVTGEYLPYADKHTSRIRNSGDKTKLISANDSLGFTYRGRFRSGREAAAVSYEVSQKGHNALKWLIDRQGVTIDGKVFLVWGIDNPDLPPPWEDGLDLYGEEEDEDTAGDAAHREFAGQFRRAIHGYRYNTDDYKSEVVIMVLDAATPGRLSIVYYRNLNKELFFNRLNYWHATCRWLHRYRKNEQKEILSFTGAPATRDIAFAAYGPQASDKVVKVLLERMLPCIVDKRPVPQDIVRSAVNRASNPVGMEPWEWEKTLSIACALVKKTYEKEGFTVSLDVENEDRSYLFGRMLAIADVLERRALGKEEKRATNAVRYMNVFAQHPGRTWEIIQSNLQPYQAKMGTKDGIINYCNKMLDEVGSRLKLEDYNDNRLNGRYLLGFYSQRNELYKSREQREAEAGQTARTDESANNDVQGENE
>NZ_CP011114.1|WP_025695201.1|619236_619959_+|type-I-C-CRISPR-associated-protein-Cas5
MRNQIEFEVYGKYGLFTDPLTKIGGEKFSYQIPTYQALKGIVESIYWKPTLIWIIDEVRVMEPIQTESKGIRPIEYGGGNTLSYYTYLKEPRYQVRAHFEFNPHREDLIQDRNEHKHHNIAKRAVQAGGRRDIFLGARECQGYVEPCEYGKGVGFYDEIAEIDFGIMVHGINYPDETGRQERETRLWRAKMEHGIIRYIRPEECTLLRKTGEGHIKSFGLADIQSVEELYADYFQGEERG
>NZ_CP011114.1|WP_025695200.1|616193_618635_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRQKDKKIQTVEEHQKEVQVGCEQYGAKIGVTHLAGLAGMLHDIGKNTNEFNTYLVKAVYHPEAASRKGSVDHSTAGGKLLYQRYHKGEGVSMNKLAAEWIGNCIISHHQGLRDFLSPQLDSPYLKRVGQKELDEYDRAVAAFFEQVPADKLDRYFEQAVAELKLALTIIQEYKLPRITLALLIKYIFSCLIDADRTNTRDFEADEHTDWIKDHQSFFLESYNRLLAKIALLNEAKDADHPINRLRREMSRQCEEFALLSSGIYTLSIPTGGGKTLASLRYALRHALETGKERIIYIVPFTTIIEQNAKEIREIIQNDDMVLEHHSNVVDEIDPGSDDYDLEKEKLKLARDHWDRPIIFTTMVQFLNTFYAKGTRNVRRLHQLSNAVLIFDEVQAVPHRCLSLFNAALNFLHTFGKSSIVLCTATQPALDDVRHKLHLSEQSEMIKNLSDVGRYFKRVELVDYTAKCGASGWGAETLASFVRERMNEVNSVLVILNTKTAVRKLFAELDQEEWAEDRKVRLFHLSTNMCAAHRKDVLAELIQVLDSKVNERVICVSTQLIEAGVNISFDCVIRSLSGLDSITQAAGRCNRHGKDPLRQVYVIQSADENLNHLQEIKIGAEMTLKVLDDFRKKPELYENDRLSPSAMKAYFKYYYHRIKDELDYPVPKLGGKKLFNLLSSNKAYYDAYRNRYSEKLGLGSLQALATAEQYFEVIDNPATSVIVPYNAEARDLIANLNGELDIWELGDLLRKAQQYVVNVYKHDLVKLDKSGELFPLLNGNVLALHDTAYSERFGVGTEGDGEWGTSII
>NZ_CP011114.1|WP_025695199.1|612813_613785_-|S-layer-homology-domain-containing-protein
MMKRQTFRHNAKKMTIACGILAGAVLFGASAFAFSDLKGDPAEAKINALHEAGVINGVTSQLFAPKSKMTYGQAVQLIVSGLALKTNPVPGSPSKASDYFAKVDDKSWYAPSLLIAVQNGLPLDKAVNPNAAVSRATFAQLLDAALKAKGDFPVTEMYFNIADGGKLSAEVNGSLQTLLNMRIISLDPGGKFRPNDAVTRSEAAAWVHDARAFVQSMFGGDGSADTSQGADINVEKAADGVNKVSVTVGNLPNPGYGLTIAKIEFGEGKKAVIYYEVTKPGPGMYPQVISKATAVAYLPEGYVASAKPMPGSYTPPEPDSPQF
>NZ_CP011114.1|WP_025694820.1|610476_612666_+|RNA-binding-transcriptional-accessory-protein
MNIVSDEAARRERQMMIGQIAKELGLSERQVGTTAGLLDEGNTIPFIARYRKEMTGELDENALRDIEERLSYLRSLGERKREVIRIIEEQGKLTDELREQIAGAVKLQEVEDLYRPYRQKRKTRASVAKEKGLGPLADWIMEQRRGGNPEAEAGKYVDPAKGVESAEQALQGAQDIIAEAIADDAAVRSWVRQFTASQGILVSEAKDKEQESVYENYYSYREPVHKMPPHRILAINRGERENVLKVSIEVDAARIHAHITRKLVKGPSPVKELLEAVAEDAYKRLIAPSVEREVRGEMTEKGENQAISIFSGNLRSLLLQPPVKGRRVLGVDPAYRTGCKLAVVDETGKLLEVAVTYPTPPHNKKREAAEKFKELIAKYGIQLIVIGNGTGSRETEQFTAETIAEIGDPGLAYLIVNEAGASVYSASKLAQEEFPDLDVAERSAASIARRVQDPLAELVKIEPKAIGVGQYQHDVSQKHLDESLTAVVESAVNHVGVDVNTASPSLLSYVAGINSTIAKNIVKFREENGSFKNRKQLQKVPRLGAKSYEQCIGFLRIPEGENTLDRTPIHPESYDVVSRLFKELGLALSQIGSKELAAELAAQNPEELAARLDVGVPTLRDILESLQRPGRDPREELPPPIFRTDVLKIEDLAPGMELQGTVRNVIDFGAFVDIGIKNDGLVHISQLSSSFVKHPMDVVSVGDNVTVWVLSVDLKKGRVSLTMRPPRGE
>NZ_CP011114.1|WP_025691534.1|609923_610274_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDASSHGFDRDSVILLEQVRTIDKQRLTDKITHLDDETMKKVDDSLQISLGLIDF
>NZ_CP011114.1|WP_025695207.1|627149_627896_+|DeoR/GlpR-transcriptional-regulator
MLTEERHGMIIQRLQEKGVVKMQELTEMLGASESTVRRDLIDLESRNLLKRVHGGASLLPHKSQELGMEEKTSKNIQQKNSIASLAAAQLLDGECIYLDAGTTTLAMISHIDAKGVTVVTNGLSHIEELVRKQIPSYLLGGMMKSHTKAVVGSIALQNMENFRFDKCFLGTNGVDAKMGYTTPDPEEALIKRRAHQLSGKTYVLADSSKFGEVAFAKLFDLQEAVVITDTVPERLRQSIASKTKIIEG
>NZ_CP011114.1|WP_025695208.1|627899_628811_+|1-phosphofructokinase
MIYTVTLNPSIDYIVEVEDLKLGDLNRMKRDLKLPGGKGINVSRVLDQLGVENTALGFLGGFTGRFIADKLREDSIKSDFVFVADDTRINIKLKHGDETEINGLGPVIRDEEAQQLLDKLSHLQQNDIVILSGSAPPSLGGDFYQKLIRACGQSGAEFVIDTTGKALMNALVHKPLLVKPNHHELAELYGVTINSVDEIITYGRKLLEEGAKHVLISMAGEGALLITEQEVYRATVPSGTVKNSVGAGDSMIAGFVGTLFLTGDPIEAFRAGVASGSATAFSDDLATKEEIERLRPQVQISKL
>NZ_CP011114.1|WP_046722766.1|628874_630848_+|PTS-fructose-transporter-subunit-IIABC
MRITDLMIKQTMIMDLKATTKEAAIDELIASLAANGRINDPVLFKQMILKREEESSTGIGGGIAMPHAKTKAVNEATVVFAKSAGGVDFESLDGEPAHLFFMIAAPEGAANTHLRTLAALSRLLIDVEFIDQLKNTKTPDDVTALFDAKQEEQEAAKKAEEEKTKQEEEAKAKQPAASGMIVGNPSNMEAFVVAVTACPTGIAHTFMAEDALKKKAKEMGINIRVETNGSEGAKNVLTPDEIRRASGVIVAADKQVEMARFDGKPVLQRPVSDGIRKPEELINKAVAGDAPIYRSQGKAASDAAPAGKISVGSKIYKDLMNGISHMLPFVVGGGILLAISFLFEQIASVDNPIVKLLQTIGGGDGAFHFLIPILAGFIAMSIGDRPALMPGIVGGFMAASSNAGFLGGLAAGFLAGYVVIGLRKVFAGIPQTLDGLKPILLYPVFGLLITGAIMYYLFDPFFSWINTGLIDVLNNLGTGNAVLLGLVLGGMMAIDMGGPFNKAAYTFAIGVFTSTGDGAMMAAVMAGGMVPPLAIALATTLFKNKFTEDERKSGITNYVLGLSFITEGAIPFAAADPMRVLTSCILGSAVAGGLTQFWKINIPAPHGGIFVAALANHALLFLLAVAIGAVISALVFGLWKKPLVEKPVEVSAKRSLV
>NZ_CP011114.1|WP_025700347.1|630959_631511_-|CGNR-zinc-finger-domain-containing-protein
MLWDDFINSYWRDWRTGDKSKDRDRLEDPQWVESWLSAHGLPALPMPDSEQLDELKELRGYLFDTVREVVEGKEPAGLPEKMNHYMAAGPVMRQAARDDDGRIKVSLMPLQANWEQVMAEIAASFASALAEKEQSRFRICDNPDCLWVYYDDTRNRSKRYCDDKACGNLMKVRRFRARKKAEQ
>NZ_CP011114.1|WP_025700349.1|631658_632153_+|DinB-family-protein
MQNKISEVLLQNWDYAMDQEDWSPPLKNALDGVSSEQALWKPQGEAANSIWETVNHLTYYKDRLLRKLKGLPNPPYLESNDATFTVTESGEEAWGQAVSRLKKVHADLREIIEALEEGAYDWGGSGHAPGEEVMSLILHDAYHTGQIVLVRKLQGSWPSKRSFN
>NZ_CP011114.1|WP_155986987.1|632335_632503_+|hypothetical-protein
MDPRYQHSSMEAEHLETPKKANSSLIASAFVEYAAYFIIFLGFLYFLVMYLFPKF
>NZ_CP011114.1|WP_090834029.1|632640_632757_-|cortex-morphogenetic-protein-CmpA
MPQWLSHQLMKAYYKKDRRQIKLLNECWFFYRDSAVKR
>NZ_CP011114.1|WP_025700351.1|632908_633268_-|hypothetical-protein
MPKMRYVILQQNQELQFVEMPEDYAYQLSALNLRLNKEIDKLTAENVPDLPLAVAECDSLELLREQYSLESGLDYINRLERAFAAIQEQNYPLISLLTEIRALQAQLEQWYEEEEERAQ
>NZ_CP011114.1|WP_025700353.1|633396_633885_+|SprT-family-protein
MTNEELQRWIERVSRESFGLPFRHKASFNSRLSSTGGRYFMKTHNIEINPHQLTAYGPEETEKIIKHELCHYHLHLAKRGYRHRDADFKALLARVGGSRYCRNLPGAKARKPMPYRYKLICTQCSAEYLRKRKVNPQRYRCGKCAGPLKLTVIEGAEPKGKR
>NZ_CP011114.1|WP_025700354.1|634028_634457_-|Lrp/AsnC-family-transcriptional-regulator
MGQTLLDEIDLLILRQLIQDSTLSHKEIGRAVHMTGQAVGARIRKLRELGVITGYSIGWDPEKLGLHVHALITVFLNSGSAHQTFLQFVASEGEIEEAYRVSGEGCYWMRARTESPERLNALLDRLLKYGNYKVSLAIGQVK

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Crispr_ID: NZ_CP011114_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_9

3703979-3704069

Orphan

Consensus_repeat	Method
GTGCGGACGCCCGCTCTCCCTGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011114_9

>merge|NZ_CP011114|9|3703979-3704069|CRISPRCasFinder
GTGCGGACGCCCGCTCTCCCTGCGGGAGTCGCTTTACTTCGTGCTTCGGCACATTTCTCTTAATACGTGCGGACGCCCGCTCTCCCTGCGG

>NZ_CP011114|9|9|3703979-3704069|CRISPRCasFinder
GTGCGGACGCCCGCTCTCCCTGCGG	GAGTCGCTTTACTTCGTGCTTCGGCACATTTCTCTTAATAC
GTGCGGACGCCCGCTCTCCCTGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025694578.1\|3707460_3708639_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694577.1\|3706949_3707309_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694580.1\|3709185_3709557_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369353
NZ_CP011114.1\|WP_025694240.1\|3699783_3701520_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP011114.1\|WP_144415259.1\|3706301_3706565_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694579.1\|3708846_3709059_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP011114.1\|WP_025694582.1\|3710299_3710515_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025688833.1\|3704157_3704475_-\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
NZ_CP011114.1\|WP_025698619.1\|3704982_3706263_+\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP011114.1\|WP_036638571.1\|3698227_3699586_-\|ATP-synthase-subunit-J	unknown	unknown	gnl\|CDD\|273349
NZ_CP011114.1\|WP_025694234.1\|3690450_3691215_-\|succinate-dehydrogenase-iron-sulfur-subunit	unknown	unknown	gnl\|CDD\|181515
NZ_CP011114.1\|WP_025694236.1\|3693090_3693759_-\|succinate-dehydrogenase-cytochrome-b558-subunit	unknown	unknown	gnl\|CDD\|239577
NZ_CP011114.1\|WP_025694235.1\|3691329_3693075_-\|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|236319
NZ_CP011114.1\|WP_025694581.1\|3709606_3710143_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694238.1\|3697533_3698214_-\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP011114.1\|WP_046723572.1\|3706545_3706743_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225253
NZ_CP011114.1\|WP_025694237.1\|3694085_3694994_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP011114.1\|WP_046723571.1\|3701713_3703774_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP011114.1\|WP_051505091.1\|3688802_3689075_-\|DUF3891-family-protein	unknown	unknown	gnl\|CDD\|379025
NZ_CP011114.1\|WP_025695902.1\|3689121_3689985_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293840

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025694580.1\|3709185_3709557_+\|hypothetical-protein	gnl\|CDD\|369353	pfam07410, Phage_Gp111, Streptococcus thermophilus bacteriophage Gp111 protein. This family consists of several Streptococcus thermophilus bacteriophage Gp111 proteins of around 110 residues in length. The function of this family is unknown.	8.31096e-13
NZ_CP011114.1\|WP_025694240.1\|3699783_3701520_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.77273e-09
NZ_CP011114.1\|WP_025694579.1\|3708846_3709059_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	5.62647e-13
NZ_CP011114.1\|WP_025688833.1\|3704157_3704475_-\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	1.91308e-50
NZ_CP011114.1\|WP_025698619.1\|3704982_3706263_+\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	2.02602e-10
NZ_CP011114.1\|WP_036638571.1\|3698227_3699586_-\|ATP-synthase-subunit-J	gnl\|CDD\|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	6.90988e-104
NZ_CP011114.1\|WP_025694234.1\|3690450_3691215_-\|succinate-dehydrogenase-iron-sulfur-subunit	gnl\|CDD\|181515	PRK08640, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	0
NZ_CP011114.1\|WP_025694236.1\|3693090_3693759_-\|succinate-dehydrogenase-cytochrome-b558-subunit	gnl\|CDD\|239577	cd03497, SQR_TypeB_1_TM, Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis SQR reduces low potential quinones such as menaquinone. SQR is also called succinate dehydrogenase (Sdh) or Complex II and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Members of this subfamily are classified as Type B as they contain one transmembrane subunit and two heme groups. The heme and quinone binding sites reside on the transmembrane subunit. The transmembrane subunit of Bacillus subtilis SQR is also called Sdh cytochrome b558 subunit. The structural arrangement allows efficient electron transfer between the catalytic subunit, through iron-sulfur centers, and the transmembrane subunit containing the electron acceptor (quinone). The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes.	4.31605e-85
NZ_CP011114.1\|WP_025694235.1\|3691329_3693075_-\|succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|236319	PRK08641, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
NZ_CP011114.1\|WP_025694238.1\|3697533_3698214_-\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	3.91587e-54
NZ_CP011114.1\|WP_046723572.1\|3706545_3706743_-\|hypothetical-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	0.0078508
NZ_CP011114.1\|WP_025694237.1\|3694085_3694994_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.59436e-41
NZ_CP011114.1\|WP_046723571.1\|3701713_3703774_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	5.4377e-161
NZ_CP011114.1\|WP_051505091.1\|3688802_3689075_-\|DUF3891-family-protein	gnl\|CDD\|379025	pfam13030, DUF3891, Protein of unknown function (DUF3891). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are approximately 250 amino acids in length.	2.09211e-33
NZ_CP011114.1\|WP_025695902.1\|3689121_3689985_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.63957e-27

>NZ_CP011114.1|WP_046723571.1|3701713_3703774_-|excinuclease-ABC-subunit-UvrC
MDYMDNIRNKLALLPDLPGCYLMKNEEGTIIYVGKAKVLKNRVRSYFTGSHNGKTQRLVADIRDFEYIVTASNMEALILECNLIKKHMPRYNVQLKDDKTFPYIKITNERHPRLEVTRRVLKDKAKYFGPYPNAYAAQQTKKLLDRMYPLRKCGAMPKEVCLYYHMDQCLAPCEKEVSKSAYEEITQSISTFLGGGHEEVKKDLQQKMQEAAEELYFERAKELRDQINYIEALMEKQNINTPDTKDRDVFGYAVDKGWMCVQILYMRQGKMIQRHSSSFPFYGEAYSDFMSYVTQYYSENPALPQEILLPEALLIEGAASVLPPEPADSGAASVDGPAAADSEEAAVRTAGAADTAAYGSGPALDGAKEDPPGEEEAPETAAETAQRAAADVEAAAAGVVDAAGGAAALQQWLGVKVMVPRRGLKKQMVRMACENGRVALEEKFRLIERDEERTSGAAQGLGQSLGLESLSRIEAFDNSNIQGANPVSAMVVFIDGKPAKKEYRKYKVRTVQGPDDYETMREVIRRRYERVLKEDLLRPDLIVVDGGRGQISAAVDILENELGLFIPVCGLVKDAKHKTAELLVGDPPEPVHLARDSEEFYLLQRIQDEVHRFAITFHREQRGKSMVTSRLDAIPGIGEKRRKLLLKHFGSLKKIKEATVEDFRPLSIGDKLARQILEALRDEEKV
>NZ_CP011114.1|WP_025694240.1|3699783_3701520_+|CPBP-family-intramembrane-metalloprotease
MNPVGQPLHQRPISKRLVFAGLIGLILFVMFQIVPSLTQEGYGNEQAISKSEARERAIRFAAEQLGYIPEPGDNWIVTYTSDSSFYGYMSRKSLLEDYSNRKLDRRYPYDTFHASLDSQEDKWANLAVDLNMYTGETAGFTRVPAGAGKQANVTEAVLTGKDESEEIVSDASLTPQEKERLAAPLLNKWGADPSRLERNFPSTGSYGLIYTDSSVKVGEAPLRYAFKFTAGEVSYFKPGFSPPEWHTDYVKSQVSSAGRFTLYGYGLPTFALGVLALIYSILRRKHTSFARGVFLSIAHFVIMMISTYNMLPETAGTGDMAARITNIVMFIIYTLYSLLMSALLYFSLVGGNGLWRKEEGLNPWPRAKEPGYGRYLMDSVYAGYIWAFVLLGVQTLMFIILQYTLHNWSTTDASQSPYNMRYAWLLPIVAWLAGLSEEAIYRLFGIRMLKKIVRSTLLASLITTLIWAFGHTLYPIYPISSRPIELTVIGLLFSYIFLRYGFIAVMFSHVVFDSVLMGITLIFMREPVNVIAGVVTIVIPLLVGYIVYLFNPPGKERGPQSPDPGPEPGPGPVPEHTI
>NZ_CP011114.1|WP_036638571.1|3698227_3699586_-|ATP-synthase-subunit-J
MASQTPKVTEFRWLKLSPPQILVIGFAIIILIGALLLMLPVSLAPGNTIAFLDAVFTSTSAACVTGLVVHDTGTFFSTFGQVVLMLLIQVGGLGFMSMATLFALVFRRRISLRERLVLQEAMNQSSMEGIVRLIRSVLIYSLVIEACGALLLTIRWAFDMPLGRAAFFGVFHAVSMFNNAGFDLFSGYRSLTGYADDPVVNIVVMFLIVSGGIGFIVMSDIMDYRRKRKLSLHSKVVLSMTAALIVTGAVVLFIFEFTNPRTLGSLGWGGKIWGAFFQSVTPRTAGANTLDMPGLRQASQFFIVILMFIGASPGSTGGGIKTTTFTIMIGAVIAMLRGRNDIVLFRYRLAQERVFKALTITLLALLLIVAVLMVLSTTEEAPFLNLLFETTSAFATVGLSLGVTPNLSAVGKILICLTMFAGRLGVLTLAYALGPKKGKELYRYPEGKMIIG
>NZ_CP011114.1|WP_025694238.1|3697533_3698214_-|TrkA-family-potassium-uptake-protein
MKAQQFVIIGLGRFGASLALELMEMGYEVLGIDHNEERVEEMTGKLTHAVMADATDEGVMRSLGVRNLDCGIVAIGDNMERSILTAILLKELGVKMVVAKAISILHGRALEKLGVDRVIFPERDMGVRVAHQLVTPHLLDYIELSKEYKIVELTVPSCMDGQSLAEINTRAKYGCSIIALNRGGGVIVAPTAHDHVNEGDIMVVIGSNESIDQFEEKAVNREEAEA
>NZ_CP011114.1|WP_025694237.1|3694085_3694994_+|LysR-family-transcriptional-regulator
MFDDLDIFAVVVEQSSLNRASRQLNLSQPALSRKISKLEERLGVTLFNRYGKRLELTEVGRLAYTYALEQRQQRFKFLEAISRFKQGEPLSVTLGASLTTIQTTLPPLVNAYMEKYPAAELKLITGKTHEIVTSVREGRSEVGLIASATAESGLRCIPLFEDQLRLVIAGNHPLAQLPRLEMEHLTALPMILFSKGTWYRRMTDDLFQRSGVQPDIRMEIDSFEAIIRLLPTIKAAALLPNSYLRPELLSGGGLASLHIKELELTQRTTCLIYRDTGDLSAAARSLVRVTEEVFHEGRPATL
>NZ_CP011114.1|WP_025694236.1|3693090_3693759_-|succinate-dehydrogenase-cytochrome-b558-subunit
MRGFYSRKIHSLLGVIPLAFFFIEHMLTNFSAVEKGAAGFKESVLWLNSLPLVFFLELLFIWVPLLYHGVYGLYIAYQSKPNLNRYNLERNWRYTFQRVSGIVTFIFIIWHLYETRVQVALGNVTHEELGGVMHDIVTQPLWLAFYIVGIVAACFHFANGLWSFLVSWGITVGPRSQRVSSYLCMGLFVLVTFMFLLSLVTFRDSDFKTAEAIAQAVNTVIQ
>NZ_CP011114.1|WP_025694235.1|3691329_3693075_-|succinate-dehydrogenase-flavoprotein-subunit
MATADIIIVGGGLAGLMATIKAAEAGVHVHLFSLVPVKRSHSVCAQGGINGAVNTKGEGDSPWVHFDDTVYGGDFLANQPPVKAMCEAAPGIIHLMDRMGVMFNRTPEGLLDFRRFGGTKHHRTAYAGATTGQQLLYALDEQVRRWEVEGFVTKHENWEFLSAVIDDEGVCRGIAAQDLRTMAIETFPADAVILASGGPGIIFGKTTNSVINTGTAASAVYQQGVHYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKYPAYGNLVPRDIATREIFNVCVDQGLGINGENMVYLDLSHKDPKELDVKLGGIIEIYEKFMGDDPRKIPMKIFPAVHYSMGGMWVDYNQMTNIPGLFAAGECEYQYHGANRLGANSLVSAIFGGMVSGPKAVEYIKGLKKSVQDVSTSVFDRYRRVQQEKYESLLGMSGTENAYVLHKELGEWMTANMTVVRHNVKLEATIGKIKELKERYRNINMSDTSGWNNQGVAFTRQLWNMLELAEAMTLGALLRNESRGAHYKPEFPKRNDEEFLKTTKASWTPDGPKISYEDVDVSLIPPRVRDYSKDK
>NZ_CP011114.1|WP_025694234.1|3690450_3691215_-|succinate-dehydrogenase-iron-sulfur-subunit
MAETAAAPKNVKFIITRQDDPQSAPYTEEFDLSYRPGMNVISALMEIQRNPVNAKGEATVPVCWESNCLEEVCGACSMVINGKPRQACAALIDNLEQPIRVEPMSTFPVVRDLVIDRTRMFNALKKVKAWIPIDGTYDLGPGPRMAEKKRQSAYELSKCMTCGVCLEACPNVNAKTDFIGPAAISQVRLFNAHPTGEMNADERLEALMTDGGIEGCGNSQNCVRACPKGIPLTTSIAEINKQTTKHMFKRWLGV
>NZ_CP011114.1|WP_025695902.1|3689121_3689985_-|MBL-fold-metallo-hydrolase
MTHHYQQLSPHVIIMHAEHETDRPILAAIAGERRTLLMDAGNSPMHAELFRKELERRGVRMPEILALTHWHWDHTFGMQAWGLPVVAHAETGRGLSSLSGLDWSDACLLELIRQGTINEGSAADIRKEFGENRDIRIIEPDILFQDRIAIDLGGVVCELVHVGGDHSSDSCFLHVREDRVLFLGDALGPSVYGGPRKYTSAAFLKLLSVAYGYNSHWYVESHGIPMSGEEFRSDLAGWEKLARIVKVFGDDRERVVREMKVFLQCDELSEDLLQGLDYFMAGQANMV
>NZ_CP011114.1|WP_051505091.1|3688802_3689075_-|DUF3891-family-protein
MICREQAGKFVMIKQHDHGLLAGKFAARFHMEQVPRKRRLDEVLYAIGNHDRGWIDLDEAPFWNDTAKAPYSFIDFPVVPKLTFYRWGLD
>NZ_CP011114.1|WP_025688833.1|3704157_3704475_-|thioredoxin
MAIVNVSDQSFNNEVQGQGTVVVDFWAPWCGPCKMLAPILDELSTELGDGVKIAKLNVDENPETASRFGVMSIPTLIFFKDGQPVDKVVGLNSKESLKNIVAKHQ
>NZ_CP011114.1|WP_025698619.1|3704982_3706263_+|S-layer-homology-domain-containing-protein
MKSKLISSFIALSLAAAPASVLADTINVNNGIINNGTMIVQFNDIKSDSWAYQAVTSMSERKVINGYEDGSFRPNNSISREEFAKMIAVTFSLDQPVTQAVYFSDVPATRWSFPYITAAKDYLTGYYPPKGKAFFDPSEPATREDVAAALVKIMELDTTNYSSRFTDENKISPQLKKYVNVAAEYNLITGYEDGTFKPLNSISRAEAAALLYRAIKSIGGSETPNEQSPNPSNQTIKTNPTGSSKTSNNGPNLWVDVVKEDTLPGGKPSILVKGETEPDATVTVNGEEVLVGFNGEFSTNIFVVEDGKYNIEVKSEYFGKTTAISKSIEFTILPPKLKLDKPDPQTTTYAEFVIWFEWVDQYDARPALYVNGEKRLYSLGGRRGNGEIYSGSVTVNLRNGENNYDLKLVDRYGKESATVTKVVYLK
>NZ_CP011114.1|WP_144415259.1|3706301_3706565_-|hypothetical-protein
MNDVLSDNARKMLRIMHAYRRHLGVMPPMWQLQRRSSRRPEQIRAALQELADERYIQWQPGAPLETVVILEAWEREEPGIRRRSRRR
>NZ_CP011114.1|WP_046723572.1|3706545_3706743_-|hypothetical-protein
MKIRTGQTIEIVYMDRSGKITQRKIKVKGIRDGRIRATCLATGAPRVFLTANILAWQPVGERRAV
>NZ_CP011114.1|WP_025694577.1|3706949_3707309_+|hypothetical-protein
MKITIKETGKSEALSIIDENTGVDFIQDFIGNYGALSDGQFTFDEETGTYIADQDTFDWWDKVVTDQTALEARIAELKEEHGYEAVDEVVNEATSVDLEDLAAAVNKALDEEFGEPAGK
>NZ_CP011114.1|WP_025694578.1|3707460_3708639_+|hypothetical-protein
MAEMSMGERFVINRGLTMGKKRIDLTGKRFGRLVVEKRSEKTIPSSPYKAFWDCICDCGTRKAVEGYWLTSGNTQSCGCLKKDQHINGSKATMLKISPRKDNKTGHTGVIKNKNGTYTAMLVFQGKAIYNGLAHTTFESAVRAREELELKYFQPVIDEYAEITAEDRKKASHQQFKVCRTPECGEVFIGGPRAFYCPGCREQRKRQQSADYQRRKRKGDVREIGSIDTCERCGKQYVVNSGLQQVCEECRPLHTSEYDRSTGIEHYRANKDRINPARNVKRRKRSDKCVVCGKKFDPVNGSTTCSGECKRKLMNQHYKDWYKRQKWKVPAEVEKFDMSDIAREIGKHKSTVRNHYLAGKLPEPDGQYPSGRNFWYRKSLANYINDAKEGGCK
>NZ_CP011114.1|WP_025694579.1|3708846_3709059_-|helix-turn-helix-transcriptional-regulator
MAISYRPLLVLLAERGMKKLDLREHLSLGPSTIAKFDKEGEYVSLEVIDKLCTFFGVQPNGIIEHIPDKE
>NZ_CP011114.1|WP_025694580.1|3709185_3709557_+|hypothetical-protein
MMRNVMVRAWEIARRAAKRFGGKVREYIAMSLKQAWSELRASASETKIVIVLDRVMKKVASMKVIVKGRIAVEHGVFETRAAYTQAYTRAVNWNVGYGVPVEMYVRNTDGSMTLDSVQETRMK
>NZ_CP011114.1|WP_025694581.1|3709606_3710143_+|hypothetical-protein
MYTITGRKFEINGWSNDVGTHMMSPPIMETTPKYANDSDDAVKAALDMLRDMKGSGMDVVEVYNDSSNADDMHYIMFFGVEHDYGPFKDFGVEVGIYDFELFKALLRTEPDLYREFIMDGDRELSEDQWIERYMTTIEGEDGGQEDATGLSVVIRKGALSEIRVERYNRCDWEYYSLR
>NZ_CP011114.1|WP_025694582.1|3710299_3710515_-|hypothetical-protein
MKVSYKVLESDADFLAASLTQVRVSVWFRLDPDPIGHLMDYGGAVEEYTTETVKIAGSRFFRHRFEFRAYG

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Crispr_ID: NZ_CP011114_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_10

4890327-4890434

Orphan

Consensus_repeat	Method
GGTCGGGGGTTCGATCCCCTCCGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011114_10

>merge|NZ_CP011114|10|4890327-4890434|CRISPRCasFinder
GGTCGGGGGTTCGATCCCCTCCGCCGCTACCATACATACGGAGGCTTAGCTCAGCTGGGAGAGCATCTGCCTTACAAGCAGAGGGTCGGGGGTTCGATCCCCTCAGCC

>NZ_CP011114|10|10|4890327-4890434|CRISPRCasFinder
GGTCGGGGGTTCGATCCCCTCCGCC	GCTACCATACATACGGAGGCTTAGCTCAGCTGGGAGAGCATCTGCCTTACAAGCAGAG
GGTCGGGGGTTCGATCCCCTCAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025696529.1\|4896301_4896829_+\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP011114.1\|WP_025696527.1\|4896893_4898075_+\|acyltransferase	unknown	unknown	gnl\|CDD\|376607
NZ_CP011114.1\|WP_046723790.1\|4881252_4883007_+\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
NZ_CP011114.1\|WP_025698828.1\|4884449_4884716_+\|pro-sigmaK-processing-inhibitor-BofA-family-protein	unknown	unknown	gnl\|CDD\|377835
NZ_CP011114.1\|WP_025696534.1\|4893658_4894597_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP011114.1\|WP_046723792.1\|4898186_4899731_-\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP011114.1\|WP_025696537.1\|4891041_4892139_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379258
NZ_CP011114.1\|WP_025695936.1\|4875980_4877234_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|183779
NZ_CP011114.1\|WP_046723788.1\|4877689_4879045_+\|transcription-termination-factor-Rho	unknown	unknown	gnl\|CDD\|236490
NZ_CP011114.1\|WP_025695903.1\|4879070_4880369_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|100105
NZ_CP011114.1\|WP_025696532.1\|4894609_4895644_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP011114.1\|WP_025696531.1\|4895651_4896305_+\|pyrophosphatase-PpaX	unknown	unknown	gnl\|CDD\|237336
NZ_CP011114.1\|WP_025694505.1\|4901375_4902047_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP011114.1\|WP_025698824.1\|4883060_4883372_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_CP011114.1\|WP_025689011.1\|4892241_4893363_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NZ_CP011114.1\|WP_025695937.1\|4874864_4875719_+\|class-II-fructose-1,6-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|169068
NZ_CP011114.1\|WP_025695904.1\|4880480_4880678_+\|50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234576
NZ_CP011114.1\|WP_036642307.1\|4884161_4884419_+\|DUF2508-family-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025698826.1\|4883375_4883975_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_CP011114.1\|WP_025694504.1\|4899849_4901211_-\|permease-DsdX	unknown	unknown	gnl\|CDD\|308194

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025696529.1\|4896301_4896829_+\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	1.38573e-30
NZ_CP011114.1\|WP_025694504.1\|4899849_4901211_-\|permease-DsdX	gnl\|CDD\|308194	pfam02447, GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter, and GntT, a high affinity transporter.	7.3919e-163
NZ_CP011114.1\|WP_046723790.1\|4881252_4883007_+\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_CP011114.1\|WP_025698828.1\|4884449_4884716_+\|pro-sigmaK-processing-inhibitor-BofA-family-protein	gnl\|CDD\|377835	pfam07441, BofA, SigmaK-factor processing regulatory protein BofA. This family contains the sigmaK-factor processing regulatory protein BofA (Bypass-of-forespore protein A) (approximately 80 residues long). During sporulation in Bacillus subtilis, transcription is controlled in the developing sporangium by a cascade of sporulation-specific transcription factors (sigma factors). Following engulfment, processing of sigmaK is inhibited by BofA. It has been suggested that this effect is exerted by alteration of the level of the SpoIVFA protein.	0.00196657
NZ_CP011114.1\|WP_025696534.1\|4893658_4894597_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.88421e-169
NZ_CP011114.1\|WP_046723792.1\|4898186_4899731_-\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP011114.1\|WP_025696537.1\|4891041_4892139_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	1.27598e-15
NZ_CP011114.1\|WP_025689011.1\|4892241_4893363_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	1.58342e-178
NZ_CP011114.1\|WP_046723788.1\|4877689_4879045_+\|transcription-termination-factor-Rho	gnl\|CDD\|236490	PRK09376, rho, transcription termination factor Rho; Provisional.	0
NZ_CP011114.1\|WP_025695903.1\|4879070_4880369_+\|radical-SAM-protein	gnl\|CDD\|100105	cd01335, Radical_SAM, Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. Mechanistically, they share the transfer of a single electron from the iron-sulfur cluster to SAM, which leads to its reductive cleavage to methionine and a 5'-deoxyadenosyl radical, which, in turn, abstracts a hydrogen from the appropriately positioned carbon atom. Depending on the enzyme, SAM is consumed during this process or it is restored and reused. Radical SAM enzymes catalyze steps in metabolism, DNA repair, the biosynthesis of vitamins and coenzymes, and the biosynthesis of many antibiotics. Examples are biotin synthase (BioB), lipoyl synthase (LipA), pyruvate formate-lyase (PFL), coproporphyrinogen oxidase (HemN), lysine 2,3-aminomutase (LAM), anaerobic ribonucleotide reductase (ARR), and MoaA, an enzyme of the biosynthesis of molybdopterin.	3.92536e-12
NZ_CP011114.1\|WP_025696532.1\|4894609_4895644_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	3.16896e-108
NZ_CP011114.1\|WP_025695936.1\|4875980_4877234_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|183779	PRK12830, PRK12830, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed.	0
NZ_CP011114.1\|WP_025694505.1\|4901375_4902047_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.00499e-36
NZ_CP011114.1\|WP_025698824.1\|4883060_4883372_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	4.56491e-45
NZ_CP011114.1\|WP_025696531.1\|4895651_4896305_+\|pyrophosphatase-PpaX	gnl\|CDD\|237336	PRK13288, PRK13288, pyrophosphatase PpaX; Provisional.	3.06608e-80
NZ_CP011114.1\|WP_025695937.1\|4874864_4875719_+\|class-II-fructose-1,6-bisphosphate-aldolase	gnl\|CDD\|169068	PRK07709, PRK07709, fructose-bisphosphate aldolase; Provisional.	4.75983e-164
NZ_CP011114.1\|WP_025695904.1\|4880480_4880678_+\|50S-ribosomal-protein-L31	gnl\|CDD\|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	1.02148e-34
NZ_CP011114.1\|WP_025696527.1\|4896893_4898075_+\|acyltransferase	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	3.41834e-18
NZ_CP011114.1\|WP_025698826.1\|4883375_4883975_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	4.56625e-125

>NZ_CP011114.1|WP_025698828.1|4884449_4884716_+|pro-sigmaK-processing-inhibitor-BofA-family-protein
MRTIAAIILILSAVLLIAVVFKKRLGWGWLGLFGSHLILAAVGLYIVDFTQLAGTVYIPLNPVTIGTVSVLGLPGVVMLVGLKITLFG
>NZ_CP011114.1|WP_036642307.1|4884161_4884419_+|DUF2508-family-protein
MKMGWWSGWLRKDDNGPGEDQDESWDVFTDVRKAQIEWERAHLMFDEAVGQDQIDYAIYILEAAERKYQIHLKHAKRIGLKSNQL
>NZ_CP011114.1|WP_025698826.1|4883375_4883975_+|recombination-protein-RecR
MYYPEPLAKLIDAFTRLPGIGPKTAARLAFHVLNMKEDETIDFAKALVSVKRNLHYCSVCCNITDTDPCRICQDKTRDVSVICVVQDSKDLVAMERTKEFNGYYHVLQGAISPMEGVGPDDIRLKELLTRLSDERVQELILATNPNIEGEATAMYISRLVRPFEVKVTRIAHGLPVGGDLEYADEVTLSKALEGRRELF
>NZ_CP011114.1|WP_025698824.1|4883060_4883372_+|YbaB/EbfC-family-nucleoid-associated-protein
MNNMNQMMKQVKKMQEQMLKAQEELGNKTVEGSSGGGVVTVQINGHKKLLSIEIKPEAVDPEDVEMLQDLVLTAVNDALTKAEELASSDMGKFTGGMKIPGLF
>NZ_CP011114.1|WP_046723790.1|4881252_4883007_+|DNA-polymerase-III-subunit-gamma/tau
MEHIALYRAWRPQAFQDMVGQQHIIQTLQNAIREQRVSHAYLFSGPRGTGKTTAAKVLAKAVNCERGPGPEPCNECPSCLRIASGAVMDVQEIDAASNRGVEEIRDLRDKVKYAPTEVRRKVYIIDEVHMLTTEAFNALLKTLEEPPAHVMFILATTEPHKLPATIISRCQRFDFRRVSLEEQTNRLKVICEKEGISAEDDALQYIARLSDGGMRDALSVLDQISSFTDGHVTYQQVLGMTGGIPAEQFARLAKAILESDMGGLLELVEQLMHEGKSADKCLENLLYYFRDLLMIKMVPGSAGLTDRVLNPAEFQDMASAFSRERLFDIVDTLNRYLGEMKYATHPQTLFEVALMKLCSPQEKESSSGVQAHINGGAAPVDHGELDVLKRQIAALEKKLEQALQSGGVPGNGRDSAASKPAGGRASAAPRISSASKLPPQMDKFIAGKDSGDFANTYKQWSQVLQAVKEEKVTVHAWFVDGEPVSMTDDAVLVAFKNTIHRETTEKSANKQVIERVLEARLGKPYRLVTVMLRDWNEASAKSAQSAPKEELRLEHEHETGEAAKEPWIDEAIQLFGEDLIVIKD
>NZ_CP011114.1|WP_025695904.1|4880480_4880678_+|50S-ribosomal-protein-L31
MQTAIQPKYNVVTVTCACGNTFEAGSVKQDLRVEICSACHPFFTGKQKFLDAGGRVDRFKKKYGI
>NZ_CP011114.1|WP_025695903.1|4879070_4880369_+|radical-SAM-protein
MHLVYADGQGNVYDHPELHGLARSGDMIVELLEEELIPLPEGATLSLLPNTRAVGMNPSTGEMLPLPEGSHAVGALLPQGFTRLCVPGYVKTDKSYKLPLFGYSAVVWKDGGFYVAAEQTDDSYKWNPLNCDRDAVRSGVNSLTSKYPENRLYGHLSNCALGYECLTSSNTFLNRWEGGVPVSYSCNAGCFGCISEQPDDSGFVSPQTRMNFRPRVEEIVEVMLEHLKTPESIISFGQGCEGEPSTQAKLIIEAIREVRSVTDMGYININTNAGLSDHIRGIVDAGLDLMRVSTISALDDHYNAYYKPRGYTLANVEKSLKYAASQGVYASINYLVFPGVTDREEEVEAMVEFVRRTGLKLIQMRNLNIDPESYLELIPPARGEILGMKTMLEIFREELPEVVIGSYTHVPPAGEARSKKAVAGVSPQIRNI
>NZ_CP011114.1|WP_046723788.1|4877689_4879045_+|transcription-termination-factor-Rho
MDLQISDLEEMKLTDLYKLAKKYQIPYYGQMKKRELIFAILRAQAEQSGLMFMEGVLEILPEGYGFLRPINYLPSAEDIYISASQIRKFDLRTGDLVSGKCRTPKENERYFGLLQVNAVNGENPASAAERLHFPALTPLYPQDKLSLEASPTHLSTRIMDLLAPVGLGQRGLLVAPPKAGKTLLLKEIANSISTNNPEIELFVLLIDERPEEVTDMQRSVKGEVVASTFDELPENHIKVAELVLQRALRLVEHKKDVVILLDSITRLARAYNLVVPPSGRTLSGGIDPAAFHRPKRFFGSARNVEEGGSLTILATALIDTGSRMDDIIYEEFKGTGNMELHLDRKLAERRIFPAIDIRRSGTRREEVLLSKEELDTIWAIRKSMNDSYDFVESFIKKLRDSKTNAEFLASFDVSGGKDSAAATASSGGTSNSGASARRPIRTKTAPVTTTT
>NZ_CP011114.1|WP_025695936.1|4875980_4877234_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKLMIGGGRPLQGMVTISGAKNSAIALIPAAILAESEVILDNLPSLSDVAVYSEILQELGAEVSWSGSQMRVDPSRVVSIPMPNGPVKKLRASYYMMGALLGRFKEATIGLPGGCNFEPRPIDQHIKGFEALGASVTNEHGAIHLYAKELRGAKIYLDVSSVGATINIMLAASRAKGSTIIENAAKEPEIIDVATLLNSMGAVIKGAGTETIRIEGVTEMHGCRHSIIPDRIQAGTYMIAAAATRGDVLIDNVIPKHLEALTAKLLEMGVQVEELDESIRVIGKMAYEPADVKALVYPGFATDLQSPMTSMLTQAKGVSVLSDFVYSNRFKHVPELLRMGAKIRVEGRSAIIEGSRLNAAKVKAADLRAGAALVIAGLTVEDGITEVTGVEYIDRGYDNLVPNLRELGAEVWREKE
>NZ_CP011114.1|WP_025695937.1|4874864_4875719_+|class-II-fructose-1,6-bisphosphate-aldolase
MPLVSMTDMLSKALAGKYAVGQYNINNLEWTQAILGAAEEEKSPVILGVSEGAARHMGGFNTVVKMVEGLIQDMKITVPVTIHLDHGSSFDKCKEAIDAGFTSVMIDGSHHPIEENIEMTKKVVDYAHSKGASVEAEVGTVGGQEDDVVGGIMYAKLEECVAIVKETGVDALAPALGSVHGPYHGEPNLGFKEMEEVRDAVKIPLVLHGGTGIPKHDIDKSISLGTSKINVNTENQIAFAKVVREVLAAKPDAYDPRTFIAPGREAIKQTVIGKIREFGSNNKA
>NZ_CP011114.1|WP_025696537.1|4891041_4892139_+|helix-turn-helix-domain-containing-protein
MDTETLRQKLEQLTGNKTGIKQFGRQQSASLFGAGQEAQERSVVYEGSLWVPLYESEGRVTALWIEKEGLSSVELQLAQFAAENYAAALKASGFKEEGETEARQLSVWLNTQLELDDDAGEIPDDIALKSRLFTDMIPFLLVSESTHGSEIAYRSLLKLIRSYFDSSALLIPLQEKEWLILIRKELLTGTEDKEELEESDDEELLAQACMGLHELIASEWVGVFHVSVSSSIIPVKGLAGAIALLRETISLGRIFQVGEYIHLPWGLQLERLVNSIPDGRRRQLLGQFGDYTAVLAEKEMLLTLETFFQMDCNVSETAKKLYIHRNTLLYRLDKIKQETGADVRSFGDAAIMKLTMLLYKVTKRK
>NZ_CP011114.1|WP_025689011.1|4892241_4893363_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MAGVRLEHIFKKYPGSDKATVIDVNLDIKDKEFLVLVGPSGCGKSTTLRMIAGLEEISEGKLFIGDRVVNDVAPKDRDIAMVFQSYALYPHMSVYQNMAFGLKLRKVKKDEIDRKVREAAKILDIEHLLERKPKALSGGQRQRVALGRAIVRDPQVFLMDEPLSNLDAKLRGQMRAEITKLVKRLETTCIYVTHDQTEAMTMGDRIVVMQAGIIQQAASPEELYNNPENLFVAGFIGSPTMNFISGTLSEVNGTIRFLAENLDVEVPGGKAQLLRSKGYIGKEIILGIRPEDIHEEPVFLEASPNTIFTGLVDVTENLGHEMLLYLSGVGKDSVIARVDGRSTTREGSKAKLAIDMNKVHMFDKQSELNILLG
>NZ_CP011114.1|WP_025696534.1|4893658_4894597_+|HPr-kinase/phosphorylase
MAKKVKVSELVQHFQLEVISGQEGLKRVITVDDLNRPGLEMAGYFEYYPEDRVQLLGKTELAFFSMLPAEERISRIRRIFDDQTPCIVITRSLDVPQELIDVSNEKGLPVLRSSMATTIFSSRLTSFLEGRLAPTATIHGVLCDVYGVGMLITGSSGIGKSETALELVKRGHRLIADDAVEIRQTSDNQLHGTAPELIRHLLEIRGVGIINVMTLFGAGAIRNHKRITLVVRLEAWQQDKQYDRLGLDEETTRIIDTDVPLVTIPVRPGRNLAVIIEVAAMNYRLKQMGFNAALQFTHKLTATISEDMDDLD
>NZ_CP011114.1|WP_025696532.1|4894609_4895644_+|prolipoprotein-diacylglyceryl-transferase
MFPLALDPIAFSIGALRVHWYGLILGFGALAGLYLAIREGKRFGIPQEFFMDMLLLGVPSAIIGARIYFVAFKWDEYRNNLLDVFKIWNGGIAIYGALIGAIICGIIYFRYKGYSFWRIADICAPALLAGQMIGRWGNFVNQEAYGGPVQETFLRSNLHLPDFIVNQMYIEKDLAYHHPTFLYESLWSLVGIVLLIVLRRQRFMRAGELFLSYFIWYSIGRFFIEGLRTDSLAFKGSSGLASFMNGLWSPMKGLGFEQGYLDPNYGNIRVSQLLSLLIIIAAVLLIIIRRTTGAAKDHYSDPIVSSKTHAADPVAAEQPGTSEQNASVPPSDPNHPPLEEDKKE
>NZ_CP011114.1|WP_025696531.1|4895651_4896305_+|pyrophosphatase-PpaX
MIECVLFDLDGTIVNTNELIISSFMYALQQHAQPAITREQMIPHMGTSLPDQLKAFTNLEDISALETSYRHYQLEHHDELIQSFPKVNETLEELRRREIKLGVVTTKIRPTTIRALEMFDLQQYMDTVVTLNDVTKLKPDPEPVLTAVRNLGVDPEKTLMVGDSGVDIQSAKAAGVLAAGVAWSLKGEDTLRKYGPDYILQDMTDLYEIIGGGTAKP
>NZ_CP011114.1|WP_025696529.1|4896301_4896829_+|acyltransferase
MSRKVTSYPVEGHNSLWSIYRTVSPWKGIRNFIFIQIARYCPILPLKNWIYRRVLGMKVGKHTAFGLMAMVDVFFPELITVGENSIIGYNTTILAHEYLIKEYRLGEVVIGENVMIGANTTILPGVTIGDGAVVAAGSVVHKDVAAGMFVGGNPLRELKGSRCPETAEEQQQEPR
>NZ_CP011114.1|WP_025696527.1|4896893_4898075_+|acyltransferase
MEQKERIPQLDIFRAISILAVLAIHATSRTLAETLNTPLFHPFLFINKFSQFAVPSFVFLSGFVLFYNYIDRPLTGKTLGKFYGRRLLYIIVPYVVFSLFYFVLKLYAGNQWSMAPQEMAVKMAKYLLTGTAYTHLYYVVIIIQFYVLFPLLLWCLQKSRRLAAWAPLIGLALQWGFVVLNKYMVNHGYWHVSKGSLVITYFSYFLLGAAIAVFYSSLKPWLVPSREGLRSGKWLLWALLWVLWVAAGIAHVELWNSNYTQKTVINSFWFEGTLNAHALLSCLVVFQISFLLYGTGLRLWSRLLSSVGAFSFGIYLVHPAVLYLYRKIDFHGGYLAYALAIAGGWLAALLLSWVIVAIAFRYIKYAWILFGSGPKRPMRQPPQNLRQEYGAMD
>NZ_CP011114.1|WP_046723792.1|4898186_4899731_-|gluconokinase
MSTQYMIGVDMGTTSTKSVLFTENGTIVTKADHGYPLYTPSPSIAEQDPEEIFRSVMYTLSAVMRQSGVEAKDILFVSFSSAMHSVIAVDKDGHPLTKCITWADNRSAEQTLRLKNELGGHELYLRTGTPIHPMSPITKLMWMREEQPELFEKAHKFISIKEYIFFKLFGDYIVDHSIASSTGMMNLERLEWDKEALNIAGIDESRLSRLVPTTYAACGLLPEASKEIGLLPDTPFIVGASDGVLSNLGVGAIEPGVVAATIGTSGAIRTVADRPVVDPKGRIFCYALTEKHWVIGGPVNNGGMLFRWVRDEFAASEVETAKRLGIDPYDVLTRIAEHVPAGSEGLLFHPYLTGERAPLWNADARGSFFGLTMNHRKEHMIRSVLEGVIFNLYTVMLAVEEQMGRPQRIMATGGFARSALWRQMMADIFDQEVVVPESFESSCLGAVVLGLYAIGRIDSLSAVFGMIGTTHRHLPNKADSGVYKQLLPIFISLFRSLESNYAAIAKFQREQARE
>NZ_CP011114.1|WP_025694504.1|4899849_4901211_-|permease-DsdX
MNSLFGLSHNATLLVWTLLVIVFLVALIAKYKWNPFVTLLLSALALGLLAGMEYQKLIKSITGGLGGTLGTIAIVIGLGTMLGKMMAESGGAERIATTLVDRFGEKRVHWAMMLVGFVVGIPVFFEVGLILLIPVVFMVARKTKMSLLQIGIPVLAGLSTVHGLVPPHPAPMIAIDAYGANLGKTILYAIIVGLPTAVIAGPLFGKFIGKRIQVQPPTELAEQFATKSVKTLPNFGITLLTILMPVILMLIGSIADILDPEAVNVFTPFAKFIGHEVIALLISAVFSFFSLGFARGFKKEDISRFTSECLAPTASIILIIGGGGAFKQVLIDSGVGGAIASLATQTHVNLIFFGWLVAALIRVATGSATVAMTTAAGIVAPVLAVSSGAPIELVVLATGAGSLILSHVNDAGFWMIKEFFGMSVVQTLKSWTVMETLLSVVALIFILILSVFI
>NZ_CP011114.1|WP_025694505.1|4901375_4902047_-|GntR-family-transcriptional-regulator
MQYPTAWLQGVSLGESIACRLRLQIINEQLKAGEVLSENRIAEEFGTSRSPVREALKSLAAEGLIRLERMGAVIVGLNLENVKELYDVRYLIESFAQQRLAGSPQDALIQQLEQTIDRMKLAVKYNDYVEFAYQDFSFHEAIILQARHTRILHLWNSIRQIVMTVILVTTEQGFAEGEERMNWVADKHRSIVEGLRSQNAETIRQVVQNYFADSMLTLGHALP

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Crispr_ID: NZ_CP011114_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_11

4909074-4909178

Orphan

Consensus_repeat	Method
TAAGGGGTTTAAGCTTTTGAGCAGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011114_11

>merge|NZ_CP011114|11|4909074-4909178|CRISPRCasFinder
TAAGGGGTTTAAGCTTTTGAGCAGGCGGAGCGGAGCCGCCGCCCCGAAGGGGCCAGAAGCGCGGCACGCGAAGGTTATAAGAGGTTTAAGCTTTTGAGCAGGCGG

>NZ_CP011114|11|11|4909074-4909178|CRISPRCasFinder
TAAGGGGTTTAAGCTTTTGAGCAGGCGG	AGCGGAGCCGCCGCCCCGAAGGGGCCAGAAGCGCGGCACGCGAAGGTTA
TAAGAGGTTTAAGCTTTTGAGCAGGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025695839.1\|4911779_4912730_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP011114.1\|WP_025695837.1\|4910183_4910909_+\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	unknown	unknown	gnl\|CDD\|235067
NZ_CP011114.1\|WP_025694506.1\|4902179_4903079_-\|decarboxylating-6-phosphogluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|236582
NZ_CP011114.1\|WP_025695844.1\|4917909_4918860_+\|ROK-family-glucokinase	unknown	unknown	gnl\|CDD\|273246
NZ_CP011114.1\|WP_025695845.1\|4918912_4919812_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|235450
NZ_CP011114.1\|WP_025695834.1\|4907470_4908088_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl\|CDD\|237288
NZ_CP011114.1\|WP_025694508.1\|4904726_4905362_+\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234971
NZ_CP011114.1\|WP_046723792.1\|4898186_4899731_-\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP011114.1\|WP_025695841.1\|4914437_4915391_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP011114.1\|WP_025695843.1\|4917482_4917665_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_158454085.1\|4915504_4917346_-\|SgrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|173872
NZ_CP011114.1\|WP_036640772.1\|4906861_4907467_+\|imidazoleglycerol-phosphate-dehydratase-HisB	unknown	unknown	gnl\|CDD\|234873
NZ_CP011114.1\|WP_025694507.1\|4903424_4904639_+\|ATP-phosphoribosyltransferase-regulatory-subunit	unknown	unknown	gnl\|CDD\|237043
NZ_CP011114.1\|WP_046723794.1\|4905564_4906872_+\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|376389
NZ_CP011114.1\|WP_025694505.1\|4901375_4902047_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP011114.1\|WP_025695838.1\|4910927_4911755_+\|histidinol-phosphatase-HisJ	unknown	unknown	gnl\|CDD\|235992
NZ_CP011114.1\|WP_025695835.1\|4908224_4908956_+\|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	unknown	unknown	gnl\|CDD\|179108
NZ_CP011114.1\|WP_025694504.1\|4899849_4901211_-\|permease-DsdX	unknown	unknown	gnl\|CDD\|308194
NZ_CP011114.1\|WP_025695836.1\|4909428_4910187_+\|imidazole-glycerol-phosphate-synthase-subunit-HisF	unknown	unknown	gnl\|CDD\|234996
NZ_CP011114.1\|WP_144415355.1\|4919869_4920811_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl\|CDD\|211689

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025695839.1\|4911779_4912730_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	7.82752e-150
NZ_CP011114.1\|WP_025695837.1\|4910183_4910909_+\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	gnl\|CDD\|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	4.73568e-115
NZ_CP011114.1\|WP_025694506.1\|4902179_4903079_-\|decarboxylating-6-phosphogluconate-dehydrogenase	gnl\|CDD\|236582	PRK09599, PRK09599, NADP-dependent phosphogluconate dehydrogenase.	0
NZ_CP011114.1\|WP_025695844.1\|4917909_4918860_+\|ROK-family-glucokinase	gnl\|CDD\|273246	TIGR00744, Glucokinase_Glucose_kinase., ROK family protein (putative glucokinase). This model models one branch of the ROK superfamily of proteins. The three members of the seed alignment for this model all have experimental evidence for activity as glucokinase, but the set of related proteins is crowded with paralogs of different or unknown function. Proteins scoring above the trusted_cutoff will show strong similarity to at least one known glucokinase and may be designated as putative glucokinases. However, definitive identification of glucokinases should be done only with extreme caution. [Unknown function, General].	1.21871e-89
NZ_CP011114.1\|WP_025695845.1\|4918912_4919812_+\|RNase-adapter-RapZ	gnl\|CDD\|235450	PRK05416, PRK05416, RNase adapter RapZ.	5.19491e-168
NZ_CP011114.1\|WP_025695834.1\|4907470_4908088_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl\|CDD\|237288	PRK13141, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	2.98583e-119
NZ_CP011114.1\|WP_025694508.1\|4904726_4905362_+\|ATP-phosphoribosyltransferase	gnl\|CDD\|234971	PRK01686, hisG, ATP phosphoribosyltransferase catalytic subunit; Reviewed.	4.06241e-120
NZ_CP011114.1\|WP_046723792.1\|4898186_4899731_-\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP011114.1\|WP_025695841.1\|4914437_4915391_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	6.94131e-156
NZ_CP011114.1\|WP_158454085.1\|4915504_4917346_-\|SgrR-family-transcriptional-regulator	gnl\|CDD\|173872	cd08507, PBP2_SgrR_like, The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold. A novel family of SgrR transcriptional regulator contains a two-domain structure with an N terminal DNA-binding domain of the winged helix family and a C-terminal solute-binding domain. The C-terminal domain shows strong homology with the ABC-type oligopeptide-binding protein family, a member of the type 2 periplasmic-binding fold protein (PBP2) superfamily that also includes the C-terminal substrate-binding domain of LysR-type transcriptional regulators. SgrR (SugaR transport-related Regulator) is negatively autoregulated and activates transcription of divergent operon SgrS, which encodes a small RNA required for recovery from glucose-phosphate stress. Hence, the small RNA SgrS and SgrR, the transcription factor that controls sgrS expression, are both required for recovery from glucose-phosphate stress. Most of periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.69401e-118
NZ_CP011114.1\|WP_036640772.1\|4906861_4907467_+\|imidazoleglycerol-phosphate-dehydratase-HisB	gnl\|CDD\|234873	PRK00951, hisB, imidazoleglycerol-phosphate dehydratase HisB.	1.06303e-126
NZ_CP011114.1\|WP_025694507.1\|4903424_4904639_+\|ATP-phosphoribosyltransferase-regulatory-subunit	gnl\|CDD\|237043	PRK12292, hisZ, ATP phosphoribosyltransferase regulatory subunit; Provisional.	5.07525e-137
NZ_CP011114.1\|WP_046723794.1\|4905564_4906872_+\|histidinol-dehydrogenase	gnl\|CDD\|376389	pfam00815, Histidinol_dh, Histidinol dehydrogenase.	0
NZ_CP011114.1\|WP_025694505.1\|4901375_4902047_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.00499e-36
NZ_CP011114.1\|WP_025695838.1\|4910927_4911755_+\|histidinol-phosphatase-HisJ	gnl\|CDD\|235992	PRK07328, PRK07328, histidinol-phosphatase; Provisional.	1.95272e-102
NZ_CP011114.1\|WP_025695835.1\|4908224_4908956_+\|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	gnl\|CDD\|179108	PRK00748, PRK00748, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Validated.	6.04731e-134
NZ_CP011114.1\|WP_025694504.1\|4899849_4901211_-\|permease-DsdX	gnl\|CDD\|308194	pfam02447, GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter, and GntT, a high affinity transporter.	7.3919e-163
NZ_CP011114.1\|WP_025695836.1\|4909428_4910187_+\|imidazole-glycerol-phosphate-synthase-subunit-HisF	gnl\|CDD\|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	7.14529e-179
NZ_CP011114.1\|WP_144415355.1\|4919869_4920811_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	1.32073e-145

>NZ_CP011114.1|WP_025695835.1|4908224_4908956_+|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase
MSSFIIYPAIDIRNGKCVRLLQGDYNQETVYGDSPLAMAKSWEEQGGEFIHLVDLDGAKAGHPVNVDIIGSIAAGVNVPVQVGGGLRTLEDVEKLLSLGVSRVIIGTAAINDREFTETVLAKYGDKVAIGIDARDGYVATHGWLNTSEVLATDLAKELASKGAETFIYTDISRDGMMQGPNVEGILAMAQASGKSVIASGGVTVQDDLLRLSAHKNSGIGGAIVGKALYTGNIKLAEALAALK
>NZ_CP011114.1|WP_025695834.1|4907470_4908088_+|imidazole-glycerol-phosphate-synthase-subunit-HisH
MTVAIVDYGIGNLHSVSKAIERLGHEPLVTGEASEILAADRVILPGVGAFGDAMDHLRQSGLDKVVKEVAAAGRQPLLGICLGMQLLFTRGEEYGSHEGLDLLPGTVVRFEPREGYKVPHMGWNKLQYLQPENPLLKGLKEGHVYFVHSYHALVEQKSDLLAVTDYGHPVTAIVGRGNVFGMQFHPEKSGELGRKLLEQFLKLEI
>NZ_CP011114.1|WP_036640772.1|4906861_4907467_+|imidazoleglycerol-phosphate-dehydratase-HisB
MENNGQQARQAGLSRKTNETDIKLSLTVDGSGQAELETDVPFLNHMLDLFTKHGQFDLSVQARGDIEIDDHHTVEDIGICLGQALREALGDKKGIKRYASVFVPMDEALAQVIIDISNRPHFEYRAEYPSQQVGSFSTEMVHEFLWKFALEARLTLHVIVHYGFNTHHMIEAVFKALGRAVDEATAIDPRVKGVPSTKGVL
>NZ_CP011114.1|WP_046723794.1|4905564_4906872_+|histidinol-dehydrogenase
MKVQSSRDFKLQRDVDYGTPEQNKAVKQIVADIKQEGDAALFRYTEKFDGARLSRDNVRVTQEELQAAYEHVEESFVSAIRAAADNIRAFHARQKRNSWMDLQPDGTILGQIIRPLQRVGVYVPGGKASYPSSVLMNVIPAQIAGVPEIVMVTPPATGGKEGIDPYILVAAAEAGVNEIYRVGGAQAVAALAFGTESIAPVDKICGPGNIYVALAKREVYGAVDIDSIAGPSEIVVLADDTAEPAYIAADLLSQAEHDEMASAILVTASQALAEAVAAEVERQLRELPREAIARASVENYGAIIVVETLEEGISVVNRLAPEHLEIVAQDPMALTGAVQNAGAIFLGPYSSEPVGDYFAGPNHIIPTNGTARFSSPVDVDDFIKKSSLIYYSKEALLRDGKTIIELARREGLEAHARAVEIRLENEAKGGEADGE
>NZ_CP011114.1|WP_025694508.1|4904726_4905362_+|ATP-phosphoribosyltransferase
MAQILKVAMPKGRIYDKAAELFRAAGLPIPPEGEASRKLVIPLPEAGMEFILAKPVDVPTYVEYGAADIGIVGKDVLLEENRDVYELLDLGIARCRMSIIGLPNWEPGIHQRVATKYPNVASRYFREQGQQVEVIKLNGSIELAPLIGLAERIVDMVETGQTLRENGLVEQQSIFGITSRLVANRVSYRMKNAEIQQLCDRLQSVIAEPAR
>NZ_CP011114.1|WP_025694507.1|4903424_4904639_+|ATP-phosphoribosyltransferase-regulatory-subunit
MSKPKGFEKPIGFRDYLPHAVSKLRKIENDVLNCMGQWGYRQIMTPTLEYYDTVGVASSTSDQKLYKLLNNRGQALVLRSEMTAPVARVVSSLLKDEPLPLRLSYHANVFRAIEEEAGREAEFYQTGVELVGDDSPEADAEVVALAIASLQAAGVGTFKIAIGHVGFLNGLFQEVAPGLPEVQEELKSHLLGRDYVAFRDALGRLSLTEEQKEEMDGLLRLRGGKEICGQALELSRHPLARASIEHLCKVWEVLEAYEVSQHVLIDLTMVGDFTYYTGMTFEGYAAELGFPVCSGGRYDNLLQQFGRSVPSTGFSLKTNRILDGVRGTEERQELPTLVQYDVLRRKEGLKESIRLRAEGHVVVTRLVSEPGDLTTADTEAGTGTADGKRYREIYTFVSFVKERS
>NZ_CP011114.1|WP_025694506.1|4902179_4903079_-|decarboxylating-6-phosphogluconate-dehydrogenase
MKLGLIGLGKMGYNLTLNLLNHGHEVIVSDLNPDPVRQLEGLGAIAAPGIAELTAQLPRPRILWVMVPAGAPVDGVVNTLSGLLDEGDIVIEGGNSHYKDSIARAEKLGESGIHFFDAGTSGGTEGAAHGACFMIGGNPEIFGTIEPLFRDLAVENGYLYAGPSGSGHFLKMIHNGIEYGMMQAIAEGFELLEKSPFDFNYEDVARVWSNGSVIRGWLMELTESAFSKDPKLSGIRGVMQSSGEGKWTVQTALDLEASTPVIALSLLMRYRSLEENTFHGKVVAALRNEFGGHAVVKEE
>NZ_CP011114.1|WP_025694505.1|4901375_4902047_-|GntR-family-transcriptional-regulator
MQYPTAWLQGVSLGESIACRLRLQIINEQLKAGEVLSENRIAEEFGTSRSPVREALKSLAAEGLIRLERMGAVIVGLNLENVKELYDVRYLIESFAQQRLAGSPQDALIQQLEQTIDRMKLAVKYNDYVEFAYQDFSFHEAIILQARHTRILHLWNSIRQIVMTVILVTTEQGFAEGEERMNWVADKHRSIVEGLRSQNAETIRQVVQNYFADSMLTLGHALP
>NZ_CP011114.1|WP_025694504.1|4899849_4901211_-|permease-DsdX
MNSLFGLSHNATLLVWTLLVIVFLVALIAKYKWNPFVTLLLSALALGLLAGMEYQKLIKSITGGLGGTLGTIAIVIGLGTMLGKMMAESGGAERIATTLVDRFGEKRVHWAMMLVGFVVGIPVFFEVGLILLIPVVFMVARKTKMSLLQIGIPVLAGLSTVHGLVPPHPAPMIAIDAYGANLGKTILYAIIVGLPTAVIAGPLFGKFIGKRIQVQPPTELAEQFATKSVKTLPNFGITLLTILMPVILMLIGSIADILDPEAVNVFTPFAKFIGHEVIALLISAVFSFFSLGFARGFKKEDISRFTSECLAPTASIILIIGGGGAFKQVLIDSGVGGAIASLATQTHVNLIFFGWLVAALIRVATGSATVAMTTAAGIVAPVLAVSSGAPIELVVLATGAGSLILSHVNDAGFWMIKEFFGMSVVQTLKSWTVMETLLSVVALIFILILSVFI
>NZ_CP011114.1|WP_046723792.1|4898186_4899731_-|gluconokinase
MSTQYMIGVDMGTTSTKSVLFTENGTIVTKADHGYPLYTPSPSIAEQDPEEIFRSVMYTLSAVMRQSGVEAKDILFVSFSSAMHSVIAVDKDGHPLTKCITWADNRSAEQTLRLKNELGGHELYLRTGTPIHPMSPITKLMWMREEQPELFEKAHKFISIKEYIFFKLFGDYIVDHSIASSTGMMNLERLEWDKEALNIAGIDESRLSRLVPTTYAACGLLPEASKEIGLLPDTPFIVGASDGVLSNLGVGAIEPGVVAATIGTSGAIRTVADRPVVDPKGRIFCYALTEKHWVIGGPVNNGGMLFRWVRDEFAASEVETAKRLGIDPYDVLTRIAEHVPAGSEGLLFHPYLTGERAPLWNADARGSFFGLTMNHRKEHMIRSVLEGVIFNLYTVMLAVEEQMGRPQRIMATGGFARSALWRQMMADIFDQEVVVPESFESSCLGAVVLGLYAIGRIDSLSAVFGMIGTTHRHLPNKADSGVYKQLLPIFISLFRSLESNYAAIAKFQREQARE
>NZ_CP011114.1|WP_025695836.1|4909428_4910187_+|imidazole-glycerol-phosphate-synthase-subunit-HisF
MLAKRIIPCLDVKDGRVVKGVNFVNLRDAGDPVELAAIYDREGADELVFLDISASVEGRATMVEVVRRTAGEISIPFTVGGGISAPEHMKTILRAGADKIGINTAAVNNPQLILEGARRFGSQCIVVAVDAKYNEAWGEWEVYTHGGRKPSGIKALEWVKEAERLGAGEILLTSMDADGTKDGFDIKLTSAVSDLVDIPVIASGGAGKIEHFYDVFTAGKADAGLAATIFHYKEIGIGDLKADLKQKGVEIR
>NZ_CP011114.1|WP_025695837.1|4910183_4910909_+|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE
MNEQQNNATTEQQEILEGIRWNEAGLLPAIVQDDTTLEVLMFAYMNPESLKLSLESGQTWFWSRSRGELWHKGGTSGNTQAITSIHYDCDSDTLLVKVKPEGPACHTGKVSCFYREFPLGSKAGAAKPQTDELYSGGSKSTEARFAVLAELERVIAEREVERPEGAYTTYLFDKGVDKILKKVGEETAETIIAAKNKDNAELRLEVSDLIYHLLVLLQERKLPLDDIMAELSARHERPRRD
>NZ_CP011114.1|WP_025695838.1|4910927_4911755_+|histidinol-phosphatase-HisJ
MHIDYHTHHERCGHAVGKLEDYVRRGIELGLKQLGLSDHLPLIHVDPAQYYPEMAMPLEELPRYVEECLALKERYRGVIDIRVGLEADYIEGYEEEIRELLAPYPWDYLIGSVHFLGEWDITDFRQVHGWEGQDPLAVYRRYYQAISMAASSGIYDIIGHMDVIKRFGYGPDTPEGQAEVKELELSALRRIADAGIAMELNASGLFKPCAEMFPAPHVLKQALELGIPLTLGSDAHDPAKLGEGLAEARKLLWDTGFRELAVFDGRRREMVSFEG
>NZ_CP011114.1|WP_025695839.1|4911779_4912730_+|ribose-phosphate-pyrophosphokinase
MQHHTLRIFSGSSNPKLAADIASRLGAELGKIKLTRFKSGEIYVHYEESIRNCDVFLVQSLSHPINELFVELLVMIDAAKRASARTVNIIVPYYGYARQERKSAPREPISAKMVADVLTTAGATRVLTLDLHAAAIQGFFNIPVDHLTALDLISGYLKAKNLPDVVVVSPDAGRASTAEKLASKLDSPFAIMIKKRPAHNESVITHVIGDVEGRTPVIIEDLIDTGTTIVNVVEGLKERGAKNSIVCATHGLFSGPAIERLDHPGIEEVVVTDSIELPADHSSRFTVLSVAPMLARAISIIIEGGSIDKLFGDAGI
>NZ_CP011114.1|WP_025695841.1|4914437_4915391_+|thioredoxin-disulfide-reductase
MYKSIVIGTGPAGLTAAIYLARANLNPLVIEGLQPGGQLTTTTEVENFPGFPEGILGPDLMDNMRKQAERFGAEFKSVWVESVDFSQRPFKVNVDGLGVLEAETVIISTGASARYLGIPGEQDNVGRGVSTCATCDGFFFRGKNIIVVGGGDSAMEEAGFLTRFASNVTLVHRREELRASKIMQDRAKENSKVSWALNRTPLEVVTGETGVKGLLVRDNESGKEELIEAAGVFVAIGHTPNTAFLGGQITTDANGYIVVRPGTTETNIPGVFACGDVQDTRYRQAISAAGSGCMAAMDAEKYLEGSMVHDWSETLDK
>NZ_CP011114.1|WP_158454085.1|4915504_4917346_-|SgrR-family-transcriptional-regulator
MLAALQFFELRSSYADRELNIPFPATVQTLTEIWHCTPRNVKIVLRKLSDLGWISWQPGLGRGNSSMLTFLADAQDILLEEAIAQTKKGDVKGALELIDRFGESAQVKNGFLEWLSGGMGFTRTLGTGTVLDTLRFPVQRSIVTLDPASIYFAFDSHIIGHIYDTLVDFDPISETFRPSIAHFWESSPDCSEWIIHLRKGVSFHHGREVTAQDVIYTFDRLRLNPERYGQSWMFTGISDIRMLDRKTVHITLTEPNYLFLHLLSVKASSILPADLCGADEAAFMRQPVGTGAFKLVRHDESICVLEAFSSHFRGRPHIDRVEIIHLSEQDAGMLKEPDWSYASCTEQNVYNGYLRKSAGPDAEWREVETISPGCSMLVFNQRKEGPQSSLAFRRALDLIIDRKQMIADLGENRIYPARGFRIQRSEAADLGTRKETAPDAAEIYRLLEQSGYRGETILLSTRIRHVTDAQWIQQRCCDFGIRMEIKVRKAEDMAGPGFSPEDDCQLYEVVLGKDEIQDLELYLQKGFFPSALPDGMRETVEASARAVMSDSDPDSRWRRLYELEELLRQSYGVLFLLHKKSNTRFHSSIQGINLNSCGWLDFRTVWFQPHSLA
>NZ_CP011114.1|WP_025695843.1|4917482_4917665_+|hypothetical-protein
MTVIHPAIAEMLMEKNREELECLADRQWRIQAAENVKSRQLKRERGTLWSLALKRISRML
>NZ_CP011114.1|WP_025695844.1|4917909_4918860_+|ROK-family-glucokinase
MSENIYVGVDLGGTAIKVGICDSEGHLLHTYEGPTGTEIGVDTVIDNIEKYVRQIVADSPYEWDQLAGVGAGVAGFTNIREGIIILAPNIGFRDVPIRAILESRLNKPVKVDNDANVAALGEAWSGAGRGVDNCVCYTLGTGVGGGIIINGKVYQGFSGLAGELGHICVVPDLEAIQCGCGKMGCLETVSSATGIIRMANDAVARGDRTTLSAVEKIAAKEVFDAAKAGDEVALRIVNRAAFYLGKSMAAVAAVLNPEVFIIGGGVSKAGEILFEEIRRVYAQVTPEPLQKDVKIISAQLGNDAGIVGAAGLLLRS
>NZ_CP011114.1|WP_025695845.1|4918912_4919812_+|RNase-adapter-RapZ
MTEEENTPSAAATLIIITGMSGAGKTIAVQSLEDLGFFCVDNLPPVLIPKFAELIEQSKGKIAKVALVIDLRGREFFTALSESLSFIKDHFTIGCEILFLDATDSVLVQRYKESRRRHPLAPKGLPLDGIRLERKMLEELKNSATQVIDTSNMKPAQLKEKIVSRYSHLGKSTLSVNITSFGFKYGIPIDADLVFDVRFLPNPHYVDHLRPHTGQDSDVYEYVMKWPETQAFLKKLLDMLQFLIPQYRKEGKAQIIIGIGCTGGKHRSVAISEYLGKMLGVSETETVSVSHRDAERDRH
>NZ_CP011114.1|WP_144415355.1|4919869_4920811_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MGGGTGLSVMLRGLKEMPLDITAIVTVADDGGSSGILRSELQMPPPGDIRNVLTAMADVEPLMADIMRYRFSSGEGLAGHSLGNLILAALTDISGDFVTAVRELSRVFAVRGRVLPAAGEAVVLNAEMTDGRIVTGESKIPEAGGRIKRVYLEPPAVEPLPEALEAIRSADAILLGPGSLYTSILPNLLVPKLAQAVVASSAVKMFICNVMTQPGETDGYTVSDHLQAVYDHIGMHLFDYVIVNNGEVPPEVQRKYAEQGARPVELDMKAIEDQRYKLIADKLVLFRTYLRHDTDKLSHHIYQLVQDWITRKR

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Crispr_ID: NZ_CP011114_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011114_12

5383857-5383950

Orphan

Consensus_repeat	Method
AAGTTTTGCGGAGCATAAGCTCCTTGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011114_12

>merge|NZ_CP011114|12|5383857-5383950|CRISPRCasFinder
AAGTTTTGCGGAGCATAAGCTCCTTGAAGTGGCAACGCAGCAAAACTCGCTTCGAAAGCATAGGCTAAGTTTTGCGGAGCATAAGCTCCTTGAA

>NZ_CP011114|12|12|5383857-5383950|CRISPRCasFinder
AAGTTTTGCGGAGCATAAGCTCCTTGAA	GTGGCAACGCAGCAAAACTCGCTTCGAAAGCATAGGCT
AAGTTTTGCGGAGCATAAGCTCCTTGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011114.1\|WP_025333069.1\|5395341_5395809_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP011114.1\|WP_144415246.1\|5380779_5381543_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP011114.1\|WP_025697828.1\|5383274_5383841_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP011114.1\|WP_025700599.1\|5393036_5393630_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP011114.1\|WP_025699744.1\|5376484_5376862_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|334619
NZ_CP011114.1\|WP_025694727.1\|5379836_5380595_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP011114.1\|WP_025694015.1\|5385659_5386346_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP011114.1\|WP_025697830.1\|5382748_5383117_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP011114.1\|WP_025694012.1\|5389312_5391745_+\|glycogen/starch/alpha-glucan-phosphorylase	unknown	unknown	gnl\|CDD\|340853
NZ_CP011114.1\|WP_025694728.1\|5379153_5379822_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP011114.1\|WP_025694013.1\|5388164_5389268_+\|glucose-1-phosphate-adenylyltransferase-subunit-GlgD	unknown	unknown	gnl\|CDD\|273966
NZ_CP011114.1\|WP_046723950.1\|5391879_5392359_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
NZ_CP011114.1\|WP_025694730.1\|5377697_5378132_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP011114.1\|WP_025694009.1\|5392582_5392882_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011114.1\|WP_025694729.1\|5378263_5379100_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270429
NZ_CP011114.1\|WP_179945348.1\|5393629_5395138_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341045
NZ_CP011114.1\|WP_025694014.1\|5386976_5388146_+\|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|179997
NZ_CP011114.1\|WP_046723948.1\|5384007_5385663_-\|HAMP-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|274368
NZ_CP011114.1\|WP_081754957.1\|5381564_5382599_-\|zinc-binding-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|176214
NZ_CP011114.1\|WP_025699746.1\|5376866_5377319_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319898

Protein	Function_ID	Function_description	E-value
NZ_CP011114.1\|WP_025333069.1\|5395341_5395809_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.9589e-24
NZ_CP011114.1\|WP_144415246.1\|5380779_5381543_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.83035e-31
NZ_CP011114.1\|WP_025697828.1\|5383274_5383841_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	5.77046e-23
NZ_CP011114.1\|WP_025700599.1\|5393036_5393630_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	3.36505e-34
NZ_CP011114.1\|WP_025699744.1\|5376484_5376862_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|334619	pfam01638, HxlR, HxlR-like helix-turn-helix. HxlR, a member of this family, is a DNA-binding protein that acts as a positive regulator of the formaldehyde-inducible hxlAB operon in Bacillus subtilis.	4.14019e-45
NZ_CP011114.1\|WP_025694727.1\|5379836_5380595_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.81105e-147
NZ_CP011114.1\|WP_025694015.1\|5385659_5386346_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.96499e-77
NZ_CP011114.1\|WP_025697830.1\|5382748_5383117_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	4.5858e-43
NZ_CP011114.1\|WP_025694012.1\|5389312_5391745_+\|glycogen/starch/alpha-glucan-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_CP011114.1\|WP_025694728.1\|5379153_5379822_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.42958e-84
NZ_CP011114.1\|WP_025694013.1\|5388164_5389268_+\|glucose-1-phosphate-adenylyltransferase-subunit-GlgD	gnl\|CDD\|273966	TIGR02092, Glycogen_biosynthesis_protein_GlgD, glucose-1-phosphate adenylyltransferase, GlgD subunit. This family is GlgD, an apparent regulatory protein that appears in an alpha2/beta2 heterotetramer with GlgC (glucose-1-phosphate adenylyltransferase, TIGR02091) in a subset of bacteria that use GlgC for glycogen biosynthesis. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	1.36855e-135
NZ_CP011114.1\|WP_046723950.1\|5391879_5392359_-\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	5.70203e-81
NZ_CP011114.1\|WP_025694730.1\|5377697_5378132_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	7.81037e-32
NZ_CP011114.1\|WP_025694729.1\|5378263_5379100_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.6912e-128
NZ_CP011114.1\|WP_179945348.1\|5393629_5395138_+\|MFS-transporter	gnl\|CDD\|341045	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including various Saccharomyces cerevisiae proteins such as azole resistance protein 1 (Azr1p), vacuolar basic amino acid transporter 1 (Vba1p), vacuolar basic amino acid transporter 5 (Vba5p), and Sge1p (also known as Nor1p, 10-N-nonyl acridine orange resistance protein, and crystal violet resistance protein). MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.67306e-64
NZ_CP011114.1\|WP_025694014.1\|5386976_5388146_+\|glucose-1-phosphate-adenylyltransferase	gnl\|CDD\|179997	PRK05293, glgC, glucose-1-phosphate adenylyltransferase; Provisional.	0
NZ_CP011114.1\|WP_046723948.1\|5384007_5385663_-\|HAMP-domain-containing-sensor-histidine-kinase	gnl\|CDD\|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	7.50298e-70
NZ_CP011114.1\|WP_081754957.1\|5381564_5382599_-\|zinc-binding-alcohol-dehydrogenase-family-protein	gnl\|CDD\|176214	cd08252, AL_MDR, Arginate lyase and other MDR family members. This group contains a structure identified as an arginate lyase. Other members are identified quinone reductases, alginate lyases, and other proteins related to the zinc-dependent dehydrogenases/reductases. QOR catalyzes the conversion of a quinone and NAD(P)H to a hydroquinone and NAD(P+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_CP011114.1\|WP_025699746.1\|5376866_5377319_-\|VOC-family-protein	gnl\|CDD\|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	1.29705e-11

>NZ_CP011114.1|WP_025697828.1|5383274_5383841_-|FAD-dependent-oxidoreductase
MYDIAVIGAGPAGASAALFAAKAGKKTLLIDNDKGMTRRGWYENYYGISEIGGPDLVETGHKQAVKFGAELIAGQAISISKSGDGFAIETDSGATYEAKHVILATGVLTDLAAQAGVETKDGTEPRIKTVVAVDASGKTNVEGIWAAGTVAGVSVHAVITAGDGAKVAINVISELNGARYVDHDVLKA
>NZ_CP011114.1|WP_025697830.1|5382748_5383117_+|helix-turn-helix-transcriptional-regulator
MLDPRRKKCSVETTLDVIGGKWKGVIIYHLLSGTKRFNELRRIYPQVTHHTLTLQLRDLEREGIIKRKSYNQVPPKVEYSLTEFGKTLEPIILLMKEWGDQYDERVNQSHQMEFNVDEQLDS
>NZ_CP011114.1|WP_081754957.1|5381564_5382599_-|zinc-binding-alcohol-dehydrogenase-family-protein
MRAVGFYKYLPIEHPESLLDIEVPKPFPKGRDILVEVKAISVNPADPIVRAYDNKVGEPPYLLGWDVAGVVEQVGPECTLFQPGDEVFYAGSLIRSGCNSEFHLVDERIVGRKPASLDFANAASLPLTTITAWEGLFDRFGISQDLEANRNKSILIIGAAGGVGSIAVQIANLAGLTVIGTASRPESIQWVNELGVNFVINHYEALLPQLHKIGFDQVDYIFCLNNTDQHWNNMTEVIAPQGKICLIVENEAPIALGLLKSKSVTVVWETMFTRSTFNTEDIEEQHRLLNRLAELVDEGKIRTTVTEKISPINAANLKLAHAKIESGKTIGKIVLGPVRKLYNS
>NZ_CP011114.1|WP_144415246.1|5380779_5381543_-|IS5-family-transposase
MRRRYELTDEEWNILEPLLPPARKKQGGRPPKDRRQMLNAVLWVARTGAPWRDLPGYYGPWSSAYSFFWRLQKANLWDEILKHVAIEPDWEQVMVDATIVRVHQHGAGAKGGKDRQAIGRSSGGLTTKIHAMVDALGYPLRFELTPGQDHDSVTGYRLLHELDFCPGEVLADRAYDTNAILELLQSRAITPVIPSKRNRRVKRPLDSEAYKERHLIECFFNKVKNYRRLATRYEKTANMFIAFLTLLSIRLWLK
>NZ_CP011114.1|WP_025694727.1|5379836_5380595_+|amino-acid-ABC-transporter-ATP-binding-protein
MIRLSGLHKSFGPLQVLKGVDVTLEEGKVLAIIGPSGSGKTTLLRCFNLLEVPDKGNISLGGITLSFDGKKLPQKDVLALRQKTGMVFQSYNLFPHMTALSNVMEGQVTVQKLSKEEARRRALELLVKVGLADKADSYPHQLSGGQQQRVAIARAMATEPELLLFDEPTSALDPELVGEVLKVIKELASEGMTMVIVTHEMKFAADVADTLIMMDGGVITEQGTPDQVLHHSSNPRTLQFLNRFVGDERSTV
>NZ_CP011114.1|WP_025694728.1|5379153_5379822_+|amino-acid-ABC-transporter-permease
MDDRKIQIVIDSLLPLLKAGVAFTIPLTLVSFALGLLLAVATALVRLSSWKIPVQIARFYVWIIRGTPLLVQLFIIFYGLPSVGITLEPFTAAVIGFTLSVGAYGSEIVRAAILSIHKGQWEAAYSVGMTRIQALRRIILPQAARVSVPPLTNSFISLVKDTSLAATITYVEMFRTAQQIAAVTYEPLLVYSEAAVFYLVFCTVLTVLQDYLEKRLSRYSAG
>NZ_CP011114.1|WP_025694729.1|5378263_5379100_+|amino-acid-ABC-transporter-substrate-binding-protein
MKKFSLILILVLTVILVAACGTNANNGSSPAASPSQSAETGSGEQSSLDTIKASGVLRIGTEGTYAPFTYHDASGKLTGFDVEIAEEVAKRLGVKAEFVETQWDGIFAGMDAKRFDAIFNEVSITDERKVKYDFSDPYIVSKAVLIVKSDNNTIQSFADLKGKKAAQSLTSNLADIARENGAEIVSTEGFNQAIDLLASGRVDATVNDGLSYLDLKKQKPDAPIKKVDEQANGSQSAAVFLKGNDELVKAVNDALASMKSDGTYLKISEKYFGEDVSK
>NZ_CP011114.1|WP_025694730.1|5377697_5378132_+|Lrp/AsnC-family-transcriptional-regulator
MDHPIDDIDRKILQLLQHNARMSISQISKEISMSQPSVKERILKLEDRKIISGYSTVFNLSNLNRGTTTFILLKTERCQELVDFCSKAKEVTDLYRISGEYNYLIKIQTASIEELAEFQDSLTKLGPSKSHISMKNILENRVLL
>NZ_CP011114.1|WP_025699746.1|5376866_5377319_-|VOC-family-protein
MSVKGLSHVAIQAKDYKGTIAFYTEVLGFKIGHHWSLPSFHIKEASMLVSPDRRTCIEVFDNEAVIPAQGKKASSEEEVAYGALLHFAFYVSDVDDIYQKAIAHGAKACVEPSQMSLGEPPLVVKNALIYSPNGEVIEFIEDVDFDRSPV
>NZ_CP011114.1|WP_025699744.1|5376484_5376862_+|winged-helix-turn-helix-transcriptional-regulator
MGDRRNKYGAKPNIESCPVETTLDVIGGKWKGIILYQLIGGTKRFNEFRRLNPGITQFMLTLQLRELERDGVVHREVYKEVPPRVEYSLTDFGRTLEPIIVSMKKWGETYKIRLKDIRTEQEEDA
>NZ_CP011114.1|WP_046723948.1|5384007_5385663_-|HAMP-domain-containing-sensor-histidine-kinase
MIGVSFLRRRLHPPRSLRGRLLAVSLLILSGLLLLIGVLQYILMRNFLYTSRAEAMHAQIRSVPREFYSGLAEGREGSIAPPFPGAAAAGPQDGPVPGSSGADAGGGNPVGAVSDNGSEASGQADGGGGPGVIWGEGRRPLLLDAHTMIALYRTDGTFTDLQAETADEASAPRMTDEEYNELLAHPVYRVTRDYKLLTAEDGTEHLAVFMILGRPYHPTGILQMTTDTASLHSVIMSQLLIYAALSAAALLGGSLLYLPALRRTLVPLSNMGRTAQVIDAGNLDVRFLASQGQTEIDQLSHSFNAMLERLETSFQSEREAKEQMRRFAADASHELRTPLTSIHGFLEVLLRGAAENKEQLYHALRSMHGESKRINKLVEDLLLLSRMDGAPQLHAKELRLDEVIGEMRPQLEMLAGDREFVFDISCGISGFYDPDKIKQVVLNLFQNAVQYTDPKTGKVTVSLQPIGSRAELTVQDNGIGIPAEHISHVFDRFYRSDPSRARRYGGSGLGLSISKSIIEAHGGEIGVTSAPGKGTVFRVILPCLQALAKNQ
>NZ_CP011114.1|WP_025694015.1|5385659_5386346_-|response-regulator-transcription-factor
MKAHQGVRLLLVDDEPHILQFLELGLINEGFDVRTAPDGLSALAVTDEFKPHVAILDIMMPGMNGFEVCRHFRNEETEVAVIMLTAKDEIDDRVKGLSIGADDYMVKPFSFDELLARIQARLRNQFPGLLGEVRCGPFVIDSRRKEIRFKETVLELSPTEYELLQHLVINHGLVLSKPMILDKVWGYDFGGEENIVEVYIRSLREKLGDKEHRIIRTLRGAGYRLDLT
>NZ_CP011114.1|WP_025694014.1|5386976_5388146_+|glucose-1-phosphate-adenylyltransferase
MKKKEMVAMLLAGGQGKRLKGLTKSIAKPAVYFGGTYRIIDFPLSNCTNSGIDTVGVLTQYEPLVLSSYIGIGSDWDLNRKNGGVFVLPPHEREDGSNWYRGTADAIYRNLKFVDQFDPEHVLILSGDHIYKMNYNTMLEYHLERKADCTISVIDVPLEEASRFGILNTEEDYKIYEFEEKPAKPKSTLASMGVYIFKWDVLRRALLDDGEESDSSHDFGKDIIPTLLSKGKSLYAYPFEGYWRDVGTVTSLWEANMDLLSDNPPLNLNDPSWRIFTRNPNQPAQYVAPGAKVSGSLINEGSIVRGEVRHSVLFYGVEIGEGSVITDSVIMPKVKIGKNVRIHRAIISENTVIEDYMEIGTDREDGDEILLIDNRSKKRKSIPANTISS
>NZ_CP011114.1|WP_025694013.1|5388164_5389268_+|glucose-1-phosphate-adenylyltransferase-subunit-GlgD
MKQLLGVINLDHELDHLNELTYFRCGAAVPFASRYRLIDFVLSNMMRADLESVGLFVRRKYRSLMDHLGDGKSWDMNRKHGGLFILPPDWNDPTDTSLGDLQHFHNNLDFFKRASAKYIVHSGSQHINTIDFQELYSYHLEKGADVTLVYKKIDHLEPEHDPCLRLEVDEDGNVLNIHHEKNHPNIYMDMFIMEKELFLEQVEYCIAHGESFFFRDAIQKRRDKLKIAAFEYTGYHAVINSVASYYKNSMKLLDQEEYTSLFHDNQVQTKIKYEAPTRYLESANVSNSLVANGCIIAGTVENSVIFRGVQIRKGARVVNSVIMQKCVIEEDAVIENVILDKDVQLSRERILVGDSKRPFVIAKSSKM
>NZ_CP011114.1|WP_025694012.1|5389312_5391745_+|glycogen/starch/alpha-glucan-phosphorylase
MFTDKEAFKKAFVDDLVGKLGKPLEEASNADVYHILGSMVRAQAGKNWANTNLKYKDGKEKQVYYFSMEFLIGRLLGNNLLNMGVLEMVRDGLAELGFSLQDVEEEEADAGLGNGGLGRLAACFLDSLASLQYAGHGCGIRYKYGLFEQKIVDGYQVELPDYWLQKDNVWEVRREDKSVEVRFWGRVEADKVGEKLVFRHKDYETVRAVPYDVPIIGADRRHVNTLRNWSAESILQPNRGFGADAGTDYHKFLEYKRAVESISEFLYPDDSEYEGKLLRLKQQYFLCSAGLQSILRFYGKLGLPLSELPDKVALHINDTHPTLVIPELMRILMDDRGLEWDEAWDLTTRMVSYTNHTILSEALEKWPVNMVRDLVPRVYLIIEEINARFCGELMKRYPGDNSRIAQMAIIYDDQVRMAHLAIVGSHSVNGVAALHTEILRKREMRLFDEMYPHRFNNKTNGITHRRWLMHANRDLAGLITEAIGPRWTTHPQEMIGLIKYCEDASFQQKVADIKRKNKLRLAEYIKSKHNVLVDPDSIFDVQVKRLHAYKRQLLNILHIMHLYNQIKASPNLDMVPRTFIFGAKAAPSYHLAKRIIKLINTVADIVDKDPDVKGKIRIFFLENYSVSLAEKIIPAADVSEQISTASKEASGTGNMKFMMNGALTIGTMDGANVEMNEMIGNDNMFLFGLRAEQVMDYYQYGGYYARDMYNSDSRLKEVLDQLITPGPICCYHHDFEQIFHSLLDNNDEFFVLKDFPSYVETQVEIDRAYRNRSEWLKKSIINIGHSGKFSSDNTISRYASEIWKIRSVPL
>NZ_CP011114.1|WP_046723950.1|5391879_5392359_-|GAF-domain-containing-protein
MFQAMPYDGTRSERFESVLTQLGALMKDEPNAIANLANASALLKFTLADTNWVGFYLYDGKELVLGPFQGLPACIRIPLGRGVCGTAANERRTLVVDDVHAFPGHIACDVASNSEVVVPLIKDGQLLGVLDVDSPLKHRFDDEERRFLERFAAMVSEVL
>NZ_CP011114.1|WP_025694009.1|5392582_5392882_+|hypothetical-protein
MRADVQNMFIGIHMLYHARERDLTVADMQTKLEKYGYRIGEREVKQELERLTQDNFLTAHGEEYSITGTGIEEYKEILAKLELLLREVRKPAKTADTAG
>NZ_CP011114.1|WP_025700599.1|5393036_5393630_+|GNAT-family-N-acetyltransferase
MEEHSGTAPELSGRRLKLRALRREDSGALLRCWSHPEAASWLGVEPLASEAEAEELIRLLLEMEHEEESLRWSIELPGGEVIGSCGYNSWQLTGAFRGEVGFELSPAFWGRGYMREALALALRYGFEEMELNRVEAQCHPANLRSSRLLSSLGFSREGTLREYRHTPSGFQDVDLYALLRRDWRDLITLEREKDNRT
>NZ_CP011114.1|WP_179945348.1|5393629_5395138_+|MFS-transporter
MLRGTSERGLILTGVLLATFLAAIEGTVTGPAGPAIAGDFEGMQWLSWIFTAYLLAMAVTTPIFGKVSDLFGRKPVFLGGTAVFLAGSLLCGVSQSMEQLVAFRALQGMGAGALIPMTFTIIGDIYSIEERAKTQGMLSSVWGISSLVGPLLGGYVVDFLSWRWIFVFNLPFGLLAIVFIARYLKENRIRRKTEIDIFGALLFAAGMGALLFGLSTGGQNFPWNSPLLIATLAASVLLLAAFWAVERRVPEPMLPLGLFRVRNIAFSTGSNLLISTLVIGLATYVPLWVQGVNGGSAALSGLLIAPLSVGWIFGSVAGGRLILRAGSRRTAMLGLALIFAGAFGLTMLSQGSPPLPLLALMLLCGIGFGYCSTVFTIIAQSSVGHSMRGASTALNTFTRSLGQTAGVAVFGSWLNLRIDQLLRGSSLSGITGEDMNKLLDPQAGAELSGTAGGVLRTALEGGLHSLFIVMAVIAALSLLISAGLRSGVPVAEQESIALKKAQ
>NZ_CP011114.1|WP_025333069.1|5395341_5395809_-|MarR-family-transcriptional-regulator
MIQSYERDTQLTLHLYRVFAKSFKSINEHAVIGSKIEGFNPTAFAVMEVLYYKGPQPIQQIGAKLLLQSGNVTYVIDKLEERGYLQRKPCPTDRRVIFAELTPEGERLMNDMYPKYSERIHLAFSGLNDEEKEQMIVLLKKMGLQAEKLSPLPRK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	900668-900725	6	0.897
NZ_CP011114_5	5.1\|605849\|30\|NZ_CP011114\|PILER-CR	605849-605878	30	NZ_CP050081	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence	312585-312614	7	0.767
NZ_CP011114_5	5.1\|605849\|30\|NZ_CP011114\|PILER-CR	605849-605878	30	NZ_CP049731	Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence	310623-310652	7	0.767
NZ_CP011114_5	5.1\|605849\|30\|NZ_CP011114\|PILER-CR	605849-605878	30	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	767976-768005	7	0.767
NZ_CP011114_5	5.1\|605849\|30\|NZ_CP011114\|PILER-CR	605849-605878	30	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	487996-488025	7	0.767
NZ_CP011114_5	5.1\|605849\|30\|NZ_CP011114\|PILER-CR	605849-605878	30	NZ_CP053206	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence	310955-310984	7	0.767
NZ_CP011114_5	5.1\|605849\|30\|NZ_CP011114\|PILER-CR	605849-605878	30	NZ_CP050092	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence	323318-323347	7	0.767
NZ_CP011114_5	5.1\|605849\|30\|NZ_CP011114\|PILER-CR	605849-605878	30	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	134731-134760	7	0.767
NZ_CP011114_5	5.1\|605849\|30\|NZ_CP011114\|PILER-CR	605849-605878	30	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	222689-222718	7	0.767
NZ_CP011114_7	7.6\|615056\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	615056-615089	34	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	207693-207726	7	0.794
NZ_CP011114_7	7.13\|615529\|37\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	615529-615565	37	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	451494-451530	7	0.811
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1553592-1553649	7	0.879
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	2547776-2547833	7	0.879
NZ_CP011114_5	5.5\|605978\|34\|NZ_CP011114\|CRISPRCasFinder,CRT	605978-606011	34	NC_012987	Methylorubrum extorquens AM1 plasmid p1METDI, complete sequence	121907-121940	8	0.765
NZ_CP011114_8	8.1\|624982\|34\|NZ_CP011114\|PILER-CR,CRISPRCasFinder,CRT	624982-625015	34	NZ_CP030177	Salmonella enterica subsp. enterica serovar Milwaukee str. SA19950795 plasmid pIncFII.2, complete sequence	13164-13197	8	0.765
NZ_CP011114_8	8.23\|626447\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	626447-626480	34	MF140434	Arthrobacter phage Wheelbite, complete genome	44617-44650	8	0.765
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1583788-1583845	8	0.862
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1618884-1618917	9	0.735
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1490395-1490428	9	0.735
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	382604-382637	9	0.735
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	382600-382633	9	0.735
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1601772-1601805	9	0.735
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP024940	Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence	942019-942052	9	0.735
NZ_CP011114_7	7.6\|615056\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	615056-615089	34	NZ_CP026738	Bacillus megaterium strain YC4-R4 plasmid unnamed2	61580-61613	9	0.735
NZ_CP011114_7	7.6\|615056\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	615056-615089	34	NZ_CP039263	Lactobacillus johnsonii strain DC22.2 plasmid pLjDC22.2_2, complete sequence	2750-2783	9	0.735
NZ_CP011114_8	8.5\|625248\|32\|NZ_CP011114\|PILER-CR,CRISPRCasFinder,CRT	625248-625279	32	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	819638-819669	9	0.719
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP016544	Planococcus donghaensis strain DSM 22276 plasmid pPD76, complete sequence	7380-7437	9	0.845
NZ_CP011114_2	2.13\|600875\|34\|NZ_CP011114\|PILER-CR,CRISPRCasFinder,CRT	600875-600908	34	MN694296	Marine virus AFVG_250M539, complete genome	36563-36596	10	0.706
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	382791-382824	10	0.706
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	559488-559521	10	0.706
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	683003-683036	10	0.706
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	382804-382837	10	0.706
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	683011-683044	10	0.706
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	614346-614379	10	0.706
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	702154-702187	10	0.706
NZ_CP011114_7	7.4\|614923\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	614923-614956	34	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	668872-668905	10	0.706
NZ_CP011114_8	8.1\|624982\|34\|NZ_CP011114\|PILER-CR,CRISPRCasFinder,CRT	624982-625015	34	MN694485	Marine virus AFVG_250M19, complete genome	27160-27193	10	0.706
NZ_CP011114_8	8.17\|626042\|35\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	626042-626076	35	KM389231	UNVERIFIED: Pseudomonas phage F_TK1718sp/PAK clone contig00003 genomic sequence	2408-2442	10	0.714
NZ_CP011114_8	8.17\|626042\|35\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	626042-626076	35	KJ959591	Pseudomonas phage PAN70, partial genome	9150-9184	10	0.714
NZ_CP011114_8	8.17\|626042\|35\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	626042-626076	35	KY707339	Pseudomonas phage JBD68, complete genome	9206-9240	10	0.714
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP033045	Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence	484370-484427	10	0.828
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP033045	Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence	485380-485437	10	0.828
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	CP031730	Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence	312640-312697	10	0.828
NZ_CP011114_7	7.6\|615056\|34\|NZ_CP011114\|CRISPRCasFinder,CRT,PILER-CR	615056-615089	34	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1046557-1046590	11	0.676
NZ_CP011114_8	8.9\|625508\|34\|NZ_CP011114\|PILER-CR,CRISPRCasFinder,CRT	625508-625541	34	NZ_CP045273	Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence	250706-250739	11	0.676
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NC_004604	Bacillus megaterium QM B1551 plasmid pBM400, complete sequence	47657-47714	15	0.741
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP041068	Bacillus megaterium strain KNU-01 plasmid pKNU_01_4, complete sequence	37432-37489	15	0.741
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	CP041516	Bacillus aryabhattai strain KNU10 plasmid unnamed, complete sequence	16631-16688	15	0.741
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP024037	Bacillus aryabhattai strain K13 plasmid unnamed2	9191-9248	16	0.724
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP026740	Bacillus megaterium strain YC4-R4 plasmid unnamed4	69536-69593	16	0.724
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP010587	Bacillus megaterium Q3 plasmid p1, complete sequence	2068-2125	16	0.724
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NZ_CP023319	Bacillus megaterium strain A plasmid p2, complete sequence	553-610	16	0.724
NZ_CP011114_10	10.1\|4890352\|58\|NZ_CP011114\|CRISPRCasFinder	4890352-4890409	58	NC_017139	Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence	90-147	16	0.724

1. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.897

-gctaccatacatacggaggcttagctcagctgggagagcatctgccttacaagcagag	CRISPR spacer
aagtcgcttaca-acggaggcttagctcagctgggagagcatctgccttacaagcagag	Protospacer
 . *  * **** **********************************************

2. spacer 5.1|605849|30|NZ_CP011114|PILER-CR matches to NZ_CP050081 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence) position: , mismatch: 7, identity: 0.767

cattattagaggcgggacgctcatgccgca	CRISPR spacer
tatcagcagaggcgggacgctcttgccgat	Protospacer
.**.* .*************** *****

3. spacer 5.1|605849|30|NZ_CP011114|PILER-CR matches to NZ_CP049731 (Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence) position: , mismatch: 7, identity: 0.767

cattattagaggcgggacgctcatgccgca	CRISPR spacer
tatcagcagaggcgggacgctcttgccgat	Protospacer
.**.* .*************** *****

4. spacer 5.1|605849|30|NZ_CP011114|PILER-CR matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cattattagaggcgggacgctcatgccgca	CRISPR spacer
tatcagcagaggcgggacgctcttgccgat	Protospacer
.**.* .*************** *****

5. spacer 5.1|605849|30|NZ_CP011114|PILER-CR matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 7, identity: 0.767

cattattagaggcgggacgctcatgccgca	CRISPR spacer
tatcagcagaggcgggacgctcttgccgat	Protospacer
.**.* .*************** *****

6. spacer 5.1|605849|30|NZ_CP011114|PILER-CR matches to NZ_CP053206 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence) position: , mismatch: 7, identity: 0.767

cattattagaggcgggacgctcatgccgca	CRISPR spacer
tatcagcagaggcgggacgctcttgccgat	Protospacer
.**.* .*************** *****

7. spacer 5.1|605849|30|NZ_CP011114|PILER-CR matches to NZ_CP050092 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence) position: , mismatch: 7, identity: 0.767

cattattagaggcgggacgctcatgccgca	CRISPR spacer
tatcagcagaggcgggacgctcttgccgat	Protospacer
.**.* .*************** *****

8. spacer 5.1|605849|30|NZ_CP011114|PILER-CR matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cattattagaggcgggacgctcatgccgca	CRISPR spacer
tatcagcagaggcgggacgctcttgccgat	Protospacer
.**.* .*************** *****

9. spacer 5.1|605849|30|NZ_CP011114|PILER-CR matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 7, identity: 0.767

cattattagaggcgggacgctcatgccgca	CRISPR spacer
tatcagcagaggcgggacgctcttgccgat	Protospacer
.**.* .*************** *****

10. spacer 7.6|615056|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 7, identity: 0.794

aattaag--gagcaaatacatatgaaaactaaaaca	CRISPR spacer
--ttgagaaaaggaaataaatatgaaaactaaaaaa	Protospacer
  **.**  .** ***** *************** *

11. spacer 7.13|615529|37|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 7, identity: 0.811

tccggagcca-catcgccgataatccgcagctccggcg	CRISPR spacer
-cgagagcagtcatcgccgataatacgcagatccggcg	Protospacer
 * .**** . ************* ***** *******

12. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.879

---gctaccatacatacggaggcttagctcagctgggagagcatctgccttacaagcaga	CRISPR spacer
cgggtcaccat---tatggaggcttagctcagctgggagagcatctgccttacaagcaga	Protospacer
   *..*****   **.*******************************************

13. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.879

---gctaccatacatacggaggcttagctcagctgggagagcatctgccttacaagcaga	CRISPR spacer
cgggtcaccat---tatggaggcttagctcagctgggagagcatctgccttacaagcaga	Protospacer
   *..*****   **.*******************************************

14. spacer 5.5|605978|34|NZ_CP011114|CRISPRCasFinder,CRT matches to NC_012987 (Methylorubrum extorquens AM1 plasmid p1METDI, complete sequence) position: , mismatch: 8, identity: 0.765

accgaaccgcgtcttgcccgtcagca-accatctc	CRISPR spacer
cacgaaccgcgcctcgcccgtcagcatgccgtcc-	Protospacer
  *********.**.*********** .**.**.

15. spacer 8.1|624982|34|NZ_CP011114|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030177 (Salmonella enterica subsp. enterica serovar Milwaukee str. SA19950795 plasmid pIncFII.2, complete sequence) position: , mismatch: 8, identity: 0.765

---atcctcgacttgttggttttttacatttttttga	CRISPR spacer
cagatttt---tttgttggttttttgtatttttttga	Protospacer
   **..*   .*************..**********

16. spacer 8.23|626447|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to MF140434 (Arthrobacter phage Wheelbite, complete genome) position: , mismatch: 8, identity: 0.765

gcccggcgtcaagcctctgcgcgctggacaactt	CRISPR spacer
tgacggcgtcaagcttctgctcgctggactgcat	Protospacer
   ***********.***** ******** .* *

17. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.862

---gctaccatacatacggaggcttagctcagctgggagagcatctgccttacaagcaga	CRISPR spacer
cgggtcaccat---catggaggcttagctcagctgggagagcatctgccttacaagcaga	Protospacer
   *..*****   .*.*******************************************

18. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatacgcgct	Protospacer
. ****  ******************** .. *

19. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatacgcgct	Protospacer
. ****  ******************** .. *

20. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.735

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatacgcgct	Protospacer
. ****  ******************** .. *

21. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatacgcgct	Protospacer
. ****  ******************** .. *

22. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.735

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatacgcgct	Protospacer
. ****  ******************** .. *

23. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024940 (Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence) position: , mismatch: 9, identity: 0.735

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
tatctctagcacgttgtccacggcgagcactgct	Protospacer
*.*** ****.***************  . * *

24. spacer 7.6|615056|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026738 (Bacillus megaterium strain YC4-R4 plasmid unnamed2) position: , mismatch: 9, identity: 0.735

aattaaggagcaaatacatatgaaaactaaaaca	CRISPR spacer
cataaaggagaaaatacatatgaaaaaaggtaaa	Protospacer
 ** ****** ***************  .. * *

25. spacer 7.6|615056|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039263 (Lactobacillus johnsonii strain DC22.2 plasmid pLjDC22.2_2, complete sequence) position: , mismatch: 9, identity: 0.735

aattaaggagcaaatacatatgaaaactaaaaca	CRISPR spacer
tttaaaggagcaaataactatgaaaactttcaaa	Protospacer
  * ************  **********   * *

26. spacer 8.5|625248|32|NZ_CP011114|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 9, identity: 0.719

ctgctggtacttcttgacgccttccgggtatt	CRISPR spacer
gtgctgtcacttcttgacgccttctgcgcgca	Protospacer
 ***** .****************.* *...

27. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP016544 (Planococcus donghaensis strain DSM 22276 plasmid pPD76, complete sequence) position: , mismatch: 9, identity: 0.845

---gctaccatacatacggaggcttagctcagctgggagagcatctgccttacaagcaga	CRISPR spacer
ggggtcaccat---tttggaggattagctcagctgggagagcatctgccttacaagcaga	Protospacer
   *..*****   * .***** *************************************

28. spacer 2.13|600875|34|NZ_CP011114|PILER-CR,CRISPRCasFinder,CRT matches to MN694296 (Marine virus AFVG_250M539, complete genome) position: , mismatch: 10, identity: 0.706

catctaaaccaagaagaaacattatcgtggcaac	CRISPR spacer
gatctaaaccaagataaaacattatcaattcttt	Protospacer
 ************* .**********.   *  .

29. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatgcgcgct	Protospacer
. ****  *******************. .. *

30. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 10, identity: 0.706

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatgcgcgct	Protospacer
. ****  *******************. .. *

31. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatgcgcgct	Protospacer
. ****  *******************. .. *

32. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatgcgcgct	Protospacer
. ****  *******************. .. *

33. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatgcgcgct	Protospacer
. ****  *******************. .. *

34. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatgcgcgct	Protospacer
. ****  *******************. .. *

35. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatgcgcgct	Protospacer
. ****  *******************. .. *

36. spacer 7.4|614923|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tgtctgtagcgcgttgtccacggcgatagatccg	CRISPR spacer
cttctggcgcgcgttgtccacggcgatgcgcgct	Protospacer
. ****  *******************. .. *

37. spacer 8.1|624982|34|NZ_CP011114|PILER-CR,CRISPRCasFinder,CRT matches to MN694485 (Marine virus AFVG_250M19, complete genome) position: , mismatch: 10, identity: 0.706

atcctcgacttgttggttttttacatttttttga	CRISPR spacer
ttgcatttgttgttggttttgtacattttgttgc	Protospacer
 * * .   *********** ******** ***

38. spacer 8.17|626042|35|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to KM389231 (UNVERIFIED: Pseudomonas phage F_TK1718sp/PAK clone contig00003 genomic sequence) position: , mismatch: 10, identity: 0.714

tagacgatcaggagtgggagctgatattccgggcg	CRISPR spacer
ctgccgatccggagtgggagctgatcttcaacggc	Protospacer
. * ***** *************** *** . *

39. spacer 8.17|626042|35|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to KJ959591 (Pseudomonas phage PAN70, partial genome) position: , mismatch: 10, identity: 0.714

tagacgatcaggagtgggagctgatattccgggcg	CRISPR spacer
ctgccgatccggagtgggagctgatcttcaacggc	Protospacer
. * ***** *************** *** . *

40. spacer 8.17|626042|35|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to KY707339 (Pseudomonas phage JBD68, complete genome) position: , mismatch: 10, identity: 0.714

tagacgatcaggagtgggagctgatattccgggcg	CRISPR spacer
ctgccgatccggagtgggagctgatcttcaacggc	Protospacer
. * ***** *************** *** . *

41. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP033045 (Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.828

----gctaccatacatacggaggcttagctcagctgggagagcatctgccttacaagcag	CRISPR spacer
aggggtcac----catatggaggattagctcagctgggagagcatctgccttacaagcag	Protospacer
    *..**    ****.***** ************************************

42. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP033045 (Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.828

gctaccatacatacggaggcttagctcagctgggagagcatctgccttacaagcagag	CRISPR spacer
ggggtcaccaaaatggaggattagctcagctgggagagcatctgccttacaagcagag	Protospacer
*  ..**.  * *.***** **************************************

43. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to CP031730 (Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.828

gctaccatacatacggaggcttagctcagctgggagagcatctgccttacaagcagag	CRISPR spacer
acacctgtttctatggaggattagctcagctgggagagcatctgccttacaagcagag	Protospacer
.*  *..* . **.***** **************************************

44. spacer 7.6|615056|34|NZ_CP011114|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 11, identity: 0.676

aattaaggagcaaatacatatgaaaactaaaaca	CRISPR spacer
cataaaggagcaattacatatgaaactattggta	Protospacer
 ** ********* *********** .   ...*

45. spacer 8.9|625508|34|NZ_CP011114|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045273 (Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence) position: , mismatch: 11, identity: 0.676

atatcctccttttgcttgtgataaggttttcttt	CRISPR spacer
gtattctcctcttgcttgtgataagttaccacgg	Protospacer
.***.*****.************** * .. .

46. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NC_004604 (Bacillus megaterium QM B1551 plasmid pBM400, complete sequence) position: , mismatch: 15, identity: 0.741

gctaccataca------tacggaggcttagctcagctgggagagcatctgccttacaagc	CRISPR spacer
------atatagatttttttggaggattagctcagctgggagagcacctgccttacaagc	Protospacer
      ***.*      * .***** ********************.*************

47. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP041068 (Bacillus megaterium strain KNU-01 plasmid pKNU_01_4, complete sequence) position: , mismatch: 15, identity: 0.741

gctaccataca------tacggaggcttagctcagctgggagagcatctgccttacaagc	CRISPR spacer
------atatagatttttttggaggattagctcagctgggagagcacctgccttacaagc	Protospacer
      ***.*      * .***** ********************.*************

48. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to CP041516 (Bacillus aryabhattai strain KNU10 plasmid unnamed, complete sequence) position: , mismatch: 15, identity: 0.741

gctaccataca------tacggaggcttagctcagctgggagagcatctgccttacaagc	CRISPR spacer
------atatagatttttttggaggattagctcagctgggagagcacctgccttacaagc	Protospacer
      ***.*      * .***** ********************.*************

49. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP024037 (Bacillus aryabhattai strain K13 plasmid unnamed2) position: , mismatch: 16, identity: 0.724

gctaccatacata-------cggaggcttagctcagctgggagagcatctgccttacaag	CRISPR spacer
-------tatatagattctttggaggattagctcagctgggagagcacctgccttacaag	Protospacer
       **.***       .***** ********************.************

50. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP026740 (Bacillus megaterium strain YC4-R4 plasmid unnamed4) position: , mismatch: 16, identity: 0.724

gctaccatacata-------cggaggcttagctcagctgggagagcatctgccttacaag	CRISPR spacer
-------tatatagattctttggaggattagctcagctgggagagcacctgccttacaag	Protospacer
       **.***       .***** ********************.************

51. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP010587 (Bacillus megaterium Q3 plasmid p1, complete sequence) position: , mismatch: 16, identity: 0.724

gctaccatacata-------cggaggcttagctcagctgggagagcatctgccttacaag	CRISPR spacer
-------tatatagattctttggaggattagctcagctgggagagcacctgccttacaag	Protospacer
       **.***       .***** ********************.************

52. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NZ_CP023319 (Bacillus megaterium strain A plasmid p2, complete sequence) position: , mismatch: 16, identity: 0.724

gctaccatacata-------cggaggcttagctcagctgggagagcatctgccttacaag	CRISPR spacer
-------tatatagattctttggaggattagctcagctgggagagcacctgccttacaag	Protospacer
       **.***       .***** ********************.************

53. spacer 10.1|4890352|58|NZ_CP011114|CRISPRCasFinder matches to NC_017139 (Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence) position: , mismatch: 16, identity: 0.724

gctaccatacata-------cggaggcttagctcagctgggagagcatctgccttacaag	CRISPR spacer
-------tatatagattctttggaggattagctcagctgggagagcacctgccttacaag	Protospacer
       **.***       .***** ********************.************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

20390 : 31479

Mollivirus(25.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025693774.1\|20390_21686_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	2.6e-22	26.9
WP_025693773.1\|21713_22607_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	2.4e-43	34.4
WP_025333142.1\|22700_22946_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	2.6e-08	40.3
WP_025693772.1\|22951_23641_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_046722590.1\|23618_25865_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.6e-163	43.3
WP_046722592.1\|25849_27346_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.3e-51	33.5
WP_025700099.1\|28008_29052_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.5e-68	45.2
WP_025700097.1\|29051_29666_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.6e-25	37.6
WP_046722594.1\|29931_31479_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.5e-77	51.6

DBSCAN-SWA_2

160315 : 221897

Caulobacter_phage(28.57%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081754741.1\|160315_160552_-\|transposase	transposase	NA	NA	NA	NA
WP_025694401.1\|160697_161447_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_025694400.1\|161728_162304_+	LysE family transporter	NA	NA	NA	NA
WP_025694399.1\|162328_163105_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_081754740.1\|163294_163831_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_025694397.1\|163945_164818_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_025694396.1\|164818_166276_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_025694394.1\|166758_167604_+	SDR family NAD(P)-dependent oxidoreductase	A0A2P0VP75	Tetraselmis_virus	4.4e-07	30.2
WP_025694393.1\|167764_168673_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_025694392.1\|168978_169710_+	hypothetical protein	NA	NA	NA	NA
WP_025694391.1\|169724_169940_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_025694390.1\|169961_171818_+	cation-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	9.4e-119	40.8
WP_081754743.1\|171952_172552_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_144415158.1\|172631_173771_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_025696905.1\|173824_174829_-	phosphotransferase	NA	NA	NA	NA
WP_082210197.1\|175128_176217_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3UZC2	Geobacillus_virus	1.7e-120	58.1
WP_025695366.1\|176451_176787_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_025695365.1\|176913_177786_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025695364.1\|177908_178808_+	DMT family transporter	NA	NA	NA	NA
WP_046722643.1\|178839_179223_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_046722645.1\|179173_181108_-	pyruvate kinase	NA	NA	NA	NA
WP_025695801.1\|181286_181673_+	DUF1801 domain-containing protein	NA	NA	NA	NA
WP_025695800.1\|181691_182573_+	aminoglycoside 6-adenylyltransferase	E4ZFP8	Streptococcus_phage	2.2e-57	41.5
WP_025695799.1\|182658_183882_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_025698578.1\|184338_184731_-	hypothetical protein	NA	NA	NA	NA
WP_025698576.1\|184746_187725_-	EndoU domain-containing protein	NA	NA	NA	NA
WP_025698574.1\|187749_188151_-	DUF4280 domain-containing protein	NA	NA	NA	NA
WP_025698572.1\|188181_188811_-	hypothetical protein	NA	NA	NA	NA
WP_025698570.1\|188813_189338_-	hypothetical protein	NA	NA	NA	NA
WP_025698568.1\|189350_190451_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_025698566.1\|190472_191996_-	hypothetical protein	NA	NA	NA	NA
WP_025698564.1\|192400_192856_-	hypothetical protein	NA	NA	NA	NA
WP_025698562.1\|192945_194793_-	glycoside hydrolase family 66 protein	NA	NA	NA	NA
WP_144415159.1\|195011_198383_-	hypothetical protein	NA	NA	NA	NA
WP_025697722.1\|198640_199162_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_025697718.1\|201666_202431_+	VWA domain-containing protein	A0A1D7XFL0	Escherichia_phage	9.8e-22	32.2
WP_025697716.1\|202473_202932_+	tellurite resistance TerB family protein	Q1MVI3	Enterobacteria_phage	5.1e-10	26.6
WP_025697715.1\|203277_203877_+	TerD family protein	K4JRX3	Caulobacter_phage	3.7e-24	34.5
WP_025697714.1\|203902_204481_+	TerD family protein	K4JRX3	Caulobacter_phage	4.8e-29	37.2
WP_025697712.1\|204547_205126_+	TerD family protein	K4JRX3	Caulobacter_phage	1.8e-28	39.8
WP_025697710.1\|205140_205722_+	TerD family protein	K4JRX3	Caulobacter_phage	5.1e-31	40.7
WP_025697708.1\|205792_207040_+	TerD family protein	NA	NA	NA	NA
WP_025697706.1\|207066_207864_+	DUF475 domain-containing protein	S5MAL1	Bacillus_phage	3.6e-59	48.9
WP_025697704.1\|207991_209203_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_036641718.1\|209279_210530_+	phosphoribosyltransferase family protein	A0A172Q0Y1	Acinetobacter_phage	3.3e-11	27.8
WP_046722653.1\|210650_211946_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_025697333.1\|212348_213485_+\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	8.8e-35	32.2
WP_025697335.1\|213481_214282_+	hypothetical protein	NA	NA	NA	NA
WP_025697337.1\|214376_215399_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_025697338.1\|215447_216098_+	hypothetical protein	NA	NA	NA	NA
WP_025697339.1\|216112_217207_+	toxic anion resistance protein	NA	NA	NA	NA
WP_025697341.1\|217732_218275_+	hypothetical protein	NA	NA	NA	NA
WP_025697343.1\|218343_218943_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_025697345.1\|219137_220061_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_025697347.1\|220112_221003_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_144415160.1\|221134_221897_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	8.8e-39	61.5

DBSCAN-SWA_3

2443785 : 2451951

Tupanvirus(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046723279.1\|2443785_2445339_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.2e-56	30.0
WP_046723280.1\|2445454_2446951_-	serine/threonine protein kinase	A0A0B5J6A8	Pandoravirus	8.1e-12	27.5
WP_025697992.1\|2447063_2448131_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_025697990.1\|2448295_2449408_-\|transposase	transposase	D2XQ03	Bacillus_virus	6.2e-150	70.2
WP_081754963.1\|2449404_2449569_-	MerR family DNA-binding transcriptional regulator	W0TXR0	Staphylococcus_phage	1.4e-05	51.2
WP_025697989.1\|2449630_2450416_-	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	2.7e-11	28.0
WP_025697988.1\|2450415_2450739_-	thioredoxin family protein	NA	NA	NA	NA
WP_025697986.1\|2450735_2451080_-	hypothetical protein	NA	NA	NA	NA
WP_025697984.1\|2451099_2451951_-	deoxyribonuclease IV	A0A1V0SID1	Klosneuvirus	1.4e-24	31.3

DBSCAN-SWA_4

2918342 : 2926421

Staphylococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025696986.1\|2918342_2919557_-	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	2.6e-08	33.3
WP_025696984.1\|2919753_2920242_-	GerW family sporulation protein	NA	NA	NA	NA
WP_025696982.1\|2920331_2921045_-	DUF2953 domain-containing protein	NA	NA	NA	NA
WP_025696988.1\|2921163_2921769_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	4.5e-14	31.9
WP_025696980.1\|2921737_2922529_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	3.7e-08	32.4
WP_025696978.1\|2922791_2923256_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.5e-44	60.0
WP_025696976.1\|2923330_2924584_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	2.8e-119	53.3
WP_025696973.1\|2924622_2925300_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.6e-36	41.8
WP_046723387.1\|2925317_2926421_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.9e-50	35.2

DBSCAN-SWA_5

3699783 : 3745590

Bacillus_phage(37.93%)

tail,plate,portal,holin,terminase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025694240.1\|3699783_3701520_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_046723571.1\|3701713_3703774_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_025688833.1\|3704157_3704475_-	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	1.8e-22	43.8
WP_025698619.1\|3704982_3706263_+	S-layer homology domain-containing protein	NA	NA	NA	NA
WP_144415259.1\|3706301_3706565_-	hypothetical protein	NA	NA	NA	NA
WP_046723572.1\|3706545_3706743_-	hypothetical protein	A0A2I7SCV7	Paenibacillus_phage	5.4e-09	50.0
WP_025694577.1\|3706949_3707309_+	hypothetical protein	NA	NA	NA	NA
WP_025694578.1\|3707460_3708639_+	hypothetical protein	A0A2I7SCF4	Paenibacillus_phage	3.8e-33	52.2
WP_025694579.1\|3708846_3709059_-	helix-turn-helix transcriptional regulator	A0A2I7SC34	Paenibacillus_phage	2.2e-16	65.7
WP_025694580.1\|3709185_3709557_+	hypothetical protein	A0A286QRF8	Streptococcus_phage	2.4e-05	40.0
WP_025694581.1\|3709606_3710143_+	hypothetical protein	NA	NA	NA	NA
WP_025694582.1\|3710299_3710515_-	hypothetical protein	NA	NA	NA	NA
WP_025694583.1\|3710536_3710758_-	helix-turn-helix transcriptional regulator	A0A0K2CYV5	Paenibacillus_phage	3.2e-10	42.0
WP_025694584.1\|3710869_3711079_+	hypothetical protein	NA	NA	NA	NA
WP_155986875.1\|3711137_3711293_+	hypothetical protein	NA	NA	NA	NA
WP_025694585.1\|3711332_3711650_+	hypothetical protein	NA	NA	NA	NA
WP_025694586.1\|3711770_3712601_+	hypothetical protein	NA	NA	NA	NA
WP_025694587.1\|3712737_3712953_-	hypothetical protein	R9TLP0	Paenibacillus_phage	4.2e-15	55.2
WP_025694588.1\|3712955_3713828_-	M15 family metallopeptidase	A0A127AWA8	Bacillus_phage	8.2e-41	64.3
WP_046724350.1\|3713839_3714247_-\|holin	phage holin family protein	A0A0N7GFE6	Paenibacillus_phage	2.4e-11	39.0
WP_025694590.1\|3714535_3714928_-	hypothetical protein	NA	NA	NA	NA
WP_025694591.1\|3714946_3716836_-	hypothetical protein	NA	NA	NA	NA
WP_144415260.1\|3716853_3717384_-	hypothetical protein	NA	NA	NA	NA
WP_025694593.1\|3717396_3718455_-	hypothetical protein	NA	NA	NA	NA
WP_025694594.1\|3718451_3719609_-\|plate	baseplate J/gp47 family protein	F8WQ01	Bacillus_phage	6.2e-36	30.9
WP_025694595.1\|3719625_3720534_-	DUF2634 domain-containing protein	A0A2K9VCK8	Lactobacillus_phage	8.6e-09	34.8
WP_025694596.1\|3720530_3720899_-	hypothetical protein	NA	NA	NA	NA
WP_025694597.1\|3720900_3721530_-	hypothetical protein	F8WPZ9	Bacillus_phage	3.0e-16	34.6
WP_025694598.1\|3721542_3722196_-	hypothetical protein	NA	NA	NA	NA
WP_025694599.1\|3722192_3723950_-	LysM peptidoglycan-binding domain-containing protein	A0A060AGJ6	Listeria_phage	1.7e-16	24.7
WP_052756012.1\|3723946_3728002_-	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_025699295.1\|3728021_3728234_-	hypothetical protein	NA	NA	NA	NA
WP_025699293.1\|3728280_3728727_-	hypothetical protein	NA	NA	NA	NA
WP_025699292.1\|3728798_3729245_-	hypothetical protein	F8WPZ3	Bacillus_phage	3.3e-30	49.3
WP_082210242.1\|3729263_3730370_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A076G918	Bacillus_phage	1.7e-11	26.2
WP_025698495.1\|3730378_3730612_-	hypothetical protein	NA	NA	NA	NA
WP_025698492.1\|3730592_3731141_-	hypothetical protein	NA	NA	NA	NA
WP_025698491.1\|3731142_3731961_-	hypothetical protein	F8WPY9	Bacillus_phage	1.0e-08	28.1
WP_025698490.1\|3731935_3732676_-	hypothetical protein	Q5ULK7	Lactobacillus_virus	1.7e-07	39.4
WP_025698488.1\|3732678_3733557_-	hypothetical protein	A0A288TYH8	Enterococcus_phage	6.0e-07	22.8
WP_025698485.1\|3733562_3733838_-	hypothetical protein	NA	NA	NA	NA
WP_025698484.1\|3733891_3735367_-	hypothetical protein	D9J0N5	Brochothrix_phage	1.4e-24	26.7
WP_025698483.1\|3735383_3736337_-	hypothetical protein	A0A288TZQ4	Enterococcus_phage	3.0e-20	31.1
WP_036642088.1\|3736354_3736567_-	hypothetical protein	A0A2D2W3S9	Mycobacterium_phage	8.7e-21	63.4
WP_025698479.1\|3736606_3737734_-	hypothetical protein	NA	NA	NA	NA
WP_025698478.1\|3737733_3739233_-\|portal	phage portal protein	A0A068EU16	Bacillus_phage	8.0e-60	35.1
WP_036642085.1\|3739248_3740499_-\|terminase	PBSX family phage terminase large subunit	A0A0S0KEN9	Bacillus_phage	7.4e-144	60.5
WP_025698474.1\|3740491_3741349_-\|terminase	terminase	D2J000	Enterococcus_phage	5.8e-31	38.1
WP_025698473.1\|3741396_3741810_-	BC1881 family protein	NA	NA	NA	NA
WP_036642100.1\|3741809_3742052_-	DUF2829 domain-containing protein	A0A1B0VMG3	Pseudomonas_phage	4.3e-24	67.5
WP_025698472.1\|3742373_3742586_-	hypothetical protein	A0A1B1P7D4	Bacillus_phage	3.2e-07	41.5
WP_025698471.1\|3742722_3744015_-	DNA modification methylase	Q6DMV0	Streptococcus_phage	3.4e-67	36.8
WP_025698470.1\|3744004_3745054_-	DNA cytosine methyltransferase	A0A1B1P7C6	Bacillus_phage	4.3e-121	59.2
WP_025698469.1\|3745050_3745590_-	transcriptional regulator	A0A1B1P7B5	Bacillus_phage	5.2e-46	48.3

DBSCAN-SWA_6

4184018 : 4264276

Brevibacillus_phage(21.43%)

transposase,tail,plate,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025695678.1\|4184018_4184720_-	M15 family metallopeptidase	A0A127AWA8	Bacillus_phage	5.1e-41	54.0
WP_025695679.1\|4184691_4185087_-	hypothetical protein	NA	NA	NA	NA
WP_025691969.1\|4185073_4185274_-	hypothetical protein	NA	NA	NA	NA
WP_036640606.1\|4185277_4185559_-	hypothetical protein	NA	NA	NA	NA
WP_025695681.1\|4185878_4186247_-	hypothetical protein	NA	NA	NA	NA
WP_025695682.1\|4186261_4187581_-	hypothetical protein	S6B1J7	Thermus_phage	2.9e-05	31.0
WP_025695683.1\|4187592_4188144_-	YmfQ family protein	S6BFJ0	Thermus_phage	3.7e-47	53.1
WP_081754851.1\|4188133_4189165_-\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	7.3e-89	52.5
WP_025695685.1\|4189193_4189613_-	DUF2634 domain-containing protein	A0A0A7RTU4	Clostridium_phage	3.5e-21	42.5
WP_025695686.1\|4189609_4189906_-	DUF2577 domain-containing protein	S5MC71	Brevibacillus_phage	2.2e-14	41.0
WP_025695687.1\|4189909_4190872_-	hypothetical protein	S5MNC9	Brevibacillus_phage	6.0e-85	47.8
WP_025695688.1\|4190911_4191661_-	LysM peptidoglycan-binding domain-containing protein	S5MUH0	Brevibacillus_phage	5.6e-46	40.1
WP_025695689.1\|4191657_4193535_-	hypothetical protein	S5MNW9	Brevibacillus_phage	1.6e-41	34.2
WP_025695690.1\|4193727_4194150_-\|portal	phage portal protein	Q708L8	Streptococcus_phage	2.3e-17	42.5
WP_025691980.1\|4194256_4194715_-\|tail	phage tail tube protein	A0A0K2CNG3	Brevibacillus_phage	2.4e-47	63.2
WP_025695691.1\|4194716_4196039_-\|tail	phage tail sheath family protein	S5MUG6	Brevibacillus_phage	1.1e-108	50.6
WP_155986910.1\|4196038_4196215_-	hypothetical protein	NA	NA	NA	NA
WP_025695692.1\|4196211_4196625_-	hypothetical protein	NA	NA	NA	NA
WP_025695693.1\|4197152_4197665_-	transcriptional regulator	A0A0C5AJ96	Bacteriophage	7.0e-40	61.7
WP_025695694.1\|4197946_4198387_+	helix-turn-helix domain-containing protein	S6C481	Thermus_phage	3.3e-22	43.2
WP_025695695.1\|4198423_4198837_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_025696923.1\|4205757_4207014_+	MFS transporter	NA	NA	NA	NA
WP_025696922.1\|4207160_4209044_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_025696920.1\|4209070_4209802_-	hypothetical protein	NA	NA	NA	NA
WP_025696919.1\|4209887_4211027_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_025696918.1\|4211051_4211759_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.3e-36	34.8
WP_025696916.1\|4211928_4213197_+	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_082210280.1\|4213300_4214260_-	hypothetical protein	NA	NA	NA	NA
WP_025697356.1\|4214428_4215661_-	ABC transporter permease	NA	NA	NA	NA
WP_025697354.1\|4215657_4216374_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-26	39.4
WP_025697352.1\|4216386_4218108_-	alkaline phosphatase	NA	NA	NA	NA
WP_025697350.1\|4218329_4220354_-	NAD-dependent DNA ligase LigA	Q332J4	Clostridium_botulinum_C_phage	1.3e-92	32.9
WP_046723652.1\|4220495_4222823_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.6e-131	41.0
WP_036642510.1\|4222900_4223611_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_025699229.1\|4223877_4225284_-	undecaprenyl-phosphate glucose phosphotransferase	NA	NA	NA	NA
WP_025699231.1\|4225280_4226228_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_025699232.1\|4226394_4226712_-	chorismate mutase	NA	NA	NA	NA
WP_025699233.1\|4226708_4227746_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_025699236.1\|4227926_4228796_-	dTDP-4-dehydrorhamnose reductase	NA	NA	NA	NA
WP_025699238.1\|4228795_4229818_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.6e-80	47.6
WP_025699239.1\|4230001_4230346_-	EamA family transporter	NA	NA	NA	NA
WP_025699240.1\|4230381_4230735_-	DUF2304 domain-containing protein	NA	NA	NA	NA
WP_025699242.1\|4230745_4231447_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_025699244.1\|4231463_4232900_-	DUF2142 domain-containing protein	NA	NA	NA	NA
WP_025699245.1\|4232921_4233488_-	hypothetical protein	NA	NA	NA	NA
WP_025699247.1\|4233465_4235700_-	glycosyltransferase	NA	NA	NA	NA
WP_025699248.1\|4235713_4236571_-	glycosyltransferase	A0A1V0SIN9	Klosneuvirus	4.9e-06	25.6
WP_025699249.1\|4236589_4237327_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.7e-16	26.9
WP_051505202.1\|4237342_4238128_-	ABC transporter permease	NA	NA	NA	NA
WP_046723655.1\|4238244_4240998_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_025699772.1\|4241108_4242209_-	glycerol dehydrogenase	NA	NA	NA	NA
WP_025699770.1\|4242349_4243243_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	5.6e-77	52.6
WP_046723657.1\|4243471_4246018_-	U32 family peptidase	Q6DW11	Phage_TP	6.8e-27	33.7
WP_025694844.1\|4246330_4247209_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	5.6e-106	66.0
WP_025694845.1\|4247228_4247789_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	9.3e-46	49.4
WP_025694846.1\|4247937_4249872_-	hypothetical protein	NA	NA	NA	NA
WP_025694847.1\|4249894_4250998_-	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	2.4e-13	30.8
WP_025694848.1\|4251177_4251387_-	hypothetical protein	NA	NA	NA	NA
WP_025694849.1\|4251961_4253596_+	ferredoxin--nitrite reductase	NA	NA	NA	NA
WP_025694850.1\|4253793_4256667_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	57.6
WP_025694851.1\|4257263_4259255_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_025694852.1\|4259434_4260214_+	flagellar motor protein	NA	NA	NA	NA
WP_025694853.1\|4260210_4261056_+	OmpA family protein	NA	NA	NA	NA
WP_025694854.1\|4261285_4262506_+	AGE family epimerase/isomerase	NA	NA	NA	NA
WP_025700192.1\|4263023_4263344_+\|transposase	transposase	NA	NA	NA	NA
WP_144415216.1\|4263355_4264276_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.3e-09	21.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011114

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection