CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP026065	Staphylococcus aureus strain FDAARGOS_19 plasmid unnamed	0 crisprs	csa3	0	0	1	0
NZ_CP026064	Staphylococcus aureus strain FDAARGOS_19 chromosome, complete genome	6 crisprs	DEDDh,cas3,WYL,csa3,DinG	4	0	14	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

34038 : 40940

Staphylococcus_phage(66.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000358995.1\|34038_34434_-	thioredoxin-dependent arsenate reductase	A0A2H4PQT9	Staphylococcus_phage	8.5e-62	86.3
WP_001834181.1\|34451_35744_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	3.0e-188	81.4
WP_000120605.1\|35740_36055_-	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4PQT4	Staphylococcus_phage	4.7e-39	73.1
WP_000633163.1\|36115_36451_-	recombinase family protein	NA	NA	NA	NA
WP_001035802.1\|36770_36983_+	hypothetical protein	NA	NA	NA	NA
WP_001670420.1\|37017_37692_-\|transposase	IS6-like element ISSau6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.8e-113	87.9
WP_000361064.1\|37786_38164_+	hypothetical protein	NA	NA	NA	NA
WP_000159128.1\|38401_38767_+	winged helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	8.5e-24	47.8
WP_000378396.1\|38759_40940_+	cadmium-translocating P-type ATPase CadA	E4ZFI9	Streptococcus_phage	9.3e-251	63.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP026064

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP026064_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026064_1

541573-541661

Orphan

Consensus_repeat	Method
AAAAGAAATTCTACAAGCAATGCGAGTTGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP026064_1

>merge|NZ_CP026064|1|541573-541661|CRISPRCasFinder
AAAAGAAATTCTACAAGCAATGCGAGTTGGGGAGCGGGCCCAAACACAGAGAATTTCGAAAAGAAATTCTACAAGCAATGCAAGTTGGG

>NZ_CP026064|1|1|541573-541661|CRISPRCasFinder
AAAAGAAATTCTACAAGCAATGCGAGTTGGG	GAGCGGGCCCAAACACAGAGAATTTCG
AAAAGAAATTCTACAAGCAATGCAAGTTGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026064.1\|WP_001037456.1\|532507_533629_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NZ_CP026064.1\|WP_000758216.1\|554157_554682_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP026064.1\|WP_000902807.1\|544496_544886_-\|YisL-family-protein	unknown	unknown	gnl\|CDD\|237465
NZ_CP026064.1\|WP_001047062.1\|535501_536371_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP026064.1\|WP_001182436.1\|542133_542958_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_CP026064.1\|WP_000172374.1\|549930_553407_-\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CP026064.1\|WP_001124516.1\|543009_544326_+\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|184103
NZ_CP026064.1\|WP_000007970.1\|554686_555262_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP026064.1\|WP_001670298.1\|536429_539039_-\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NZ_CP026064.1\|WP_001044227.1\|539242_541057_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP026064.1\|WP_000700883.1\|532014_532530_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|224793
NZ_CP026064.1\|WP_000404426.1\|533621_534263_-\|L-threonylcarbamoyladenylate-synthase	unknown	unknown	gnl\|CDD\|223088
NZ_CP026064.1\|WP_000711894.1\|553566_554142_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP026064.1\|WP_000619353.1\|534246_535392_-\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|223197
NZ_CP026064.1\|WP_000154918.1\|546276_549930_-\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP026064.1\|WP_000769692.1\|531269_531704_-\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NZ_CP026064.1\|WP_000682088.1\|530827_531013_+\|YjzD-family-protein	unknown	unknown	gnl\|CDD\|371396
NZ_CP026064.1\|WP_001100526.1\|529591_530533_-\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475
NZ_CP026064.1\|WP_000670755.1\|545210_546113_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP026064.1\|WP_000390575.1\|541711_542020_-\|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl\|CDD\|225062

Protein	Function_ID	Function_description	E-value
NZ_CP026064.1\|WP_001037456.1\|532507_533629_-\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.7725e-05
NZ_CP026064.1\|WP_000758216.1\|554157_554682_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	6.16967e-49
NZ_CP026064.1\|WP_000902807.1\|544496_544886_-\|YisL-family-protein	gnl\|CDD\|237465	PRK13673, PRK13673, hypothetical protein; Provisional.	2.91098e-33
NZ_CP026064.1\|WP_001047062.1\|535501_536371_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.64595e-38
NZ_CP026064.1\|WP_001182436.1\|542133_542958_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.66336e-85
NZ_CP026064.1\|WP_000172374.1\|549930_553407_-\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP026064.1\|WP_001124516.1\|543009_544326_+\|CoA-disulfide-reductase	gnl\|CDD\|184103	PRK13512, PRK13512, coenzyme A disulfide reductase; Provisional.	0
NZ_CP026064.1\|WP_000007970.1\|554686_555262_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.59702e-40
NZ_CP026064.1\|WP_001670298.1\|536429_539039_-\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_CP026064.1\|WP_001044227.1\|539242_541057_-\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	4.21639e-82
NZ_CP026064.1\|WP_000700883.1\|532014_532530_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	7.30186e-43
NZ_CP026064.1\|WP_000404426.1\|533621_534263_-\|L-threonylcarbamoyladenylate-synthase	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	7.08013e-56
NZ_CP026064.1\|WP_000711894.1\|553566_554142_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	9.57816e-54
NZ_CP026064.1\|WP_000619353.1\|534246_535392_-\|2-isopropylmalate-synthase	gnl\|CDD\|223197	COG0119, LeuA, Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism].	1.29632e-86
NZ_CP026064.1\|WP_000154918.1\|546276_549930_-\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP026064.1\|WP_000769692.1\|531269_531704_-\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	1.04833e-34
NZ_CP026064.1\|WP_000682088.1\|530827_531013_+\|YjzD-family-protein	gnl\|CDD\|371396	pfam11151, DUF2929, Protein of unknown function (DUF2929). This family of proteins with unknown function appears to be restricted to Firmicutes.	3.295e-11
NZ_CP026064.1\|WP_001100526.1\|529591_530533_-\|ketoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	0
NZ_CP026064.1\|WP_000670755.1\|545210_546113_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.74159e-87
NZ_CP026064.1\|WP_000390575.1\|541711_542020_-\|metal-sulfur-cluster-assembly-factor	gnl\|CDD\|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	1.55915e-41

>NZ_CP026064.1|WP_001044227.1|539242_541057_-|acetyltransferase
MNKTKGFTKYKKMRYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSDNIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYVIDSIGSLSFIILILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWYKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
>NZ_CP026064.1|WP_001670298.1|536429_539039_-|ATP-dependent-chaperone-ClpB
MDINKMTYAVQNALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQYGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEALAKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELDLSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLDESRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETEREKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKETGEITESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIEVSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE
>NZ_CP026064.1|WP_001047062.1|535501_536371_+|LysR-family-transcriptional-regulator
MNLDWYYTFVILAKTLNYRLASEEINLTIPSIHKQIKNLEQHLNVKLFETYKNQIILTEDGHTFLPIAQSFIEQYESGIKHIQLKKTMFQSKLNVVVSSYIATFIMPKFLKSFFNEHPFIDVSLHVKNENIEKDINNHTYDIGISRNQPKLREVHSEKVCEGKIVLIAPNKENNHLLTEASLFEKYKIISDNHPEYWSSLKNNILNIYEKAQFLSINDVHTSIKLIEMNQGISFLPIYITTDSDYNISVINTKILQAPISFTYIYSKKESPEILAFIRSFKKYIANEQL
>NZ_CP026064.1|WP_000619353.1|534246_535392_-|2-isopropylmalate-synthase
MIRIQDNTIRDGMQQSNVRKSIIVKKEVLQEINKISINSVEVGMCTTFEDEYNIHQYREILNNDKEIVVLTRLDENEINKILNLKIHNLAVKILLPISDLHIKEKLNFTSEYYNERINKCLNMIKVNQVAIDICFEDATRCSLEKLCEYMEMISKFPIRTVTFADTVGCSTPFEYGNIFKEFVKKYPNITFSAHCHNDLGLATANTFAAILNGAQQIETTFLGIGERAGNASIEEIIAILTKKQIVMTSLNLPDIYKTSMNISKILDIRLAENKPVIGKNIFKHESGIHQDGTNKNISMYQYILPSDLGLKNSKAVQFPISNISSKKILKNKFKSIVHPKDIEENISFYKLINKFIPEVVPEDTADLLQVIKGRSKDGNFK
>NZ_CP026064.1|WP_000404426.1|533621_534263_-|L-threonylcarbamoyladenylate-synthase
MEILNESVESFEKLYLQLQNSYPIIVPTDTNYNLCSLPNNKICIDRIFKYKKRSKDKPLSLFIDEPEDWKLYGENKNVELVDKLVNIFWPGPLNIILKNKTNYNYMLNNSDSIAIGCVQNKTMRNLISYIQSPIAITSANISGTADDILITENEAIKHMGNNVNYMLRSKNKSKYKSSSTIIKVTGNKIELLREGDIKFEEIKAKLGSGIQYE
>NZ_CP026064.1|WP_001037456.1|532507_533629_-|MFS-transporter
MNKLILGIYLYRILSRAYFYLPFLLIYFLAQNYSIMQLEILMATYGVAAFLFGLYKEKIFRIYQIKDAYKLIVSEVFKIIGLILLLYPSHFYILLVAQLLLGLSYSIMAGVDTSIIKMNIKNHKLIQNKSNGYMFLSLLISGIIGSYLYGINIKWPIYMTGLFSILTILVILLTLVENVDCNIKSESKRKRKKLLADEKFWVLHYSFLRALILGFFVGFIPINLYIDLKLNNVQFISVLTSYTIMGYISSRYLTRYLNYKFLSEICLVIFLIIYTFQNIIAITIAILFLGISSGLTRPQTINELSNSSNLAAILNYAETLYFIFNIAFLLIGGYLYSIGTIQYLMLFMSLLTFIYLLTLFYLRRDQHENQHRI
>NZ_CP026064.1|WP_000700883.1|532014_532530_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MKINTEFKGNNIPYEYAAGADISDLINGNPIKSFPFEITELPKDTKYLAWSLIDYDAIPVCGFAWIHWSVANVSVTRDSISIKPDLSRTKGDYVQGKNSFTSGLLADDFSEIENHYVGPTPPDQDHQYELTVYALDHSLNLKNGFYLNEFLKEVNQHKIDQTSINLIGRKI
>NZ_CP026064.1|WP_000769692.1|531269_531704_-|MAP-domain-containing-protein
MKLKSFITVTLALGMIATTGATVASNEVSAAEKDKQPATQKAKEMQNVPYTIAVDGIMAFNQSYLNLPKDSQLSYLDLGNKVKALLYDERGVTPEKIRNAKSAVYTITWKDSSKKEVDLKKDSYTANLFDSNSIKQIDINVKTK
>NZ_CP026064.1|WP_000682088.1|530827_531013_+|YjzD-family-protein
MKHLVTFFWALLLMQMVNFVLNSLVGGDSLNLVNPIIMAVLFTIFTAIFAAVIKPPKDSSQ
>NZ_CP026064.1|WP_001100526.1|529591_530533_-|ketoacyl-ACP-synthase-III
MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK
>NZ_CP026064.1|WP_000390575.1|541711_542020_-|metal-sulfur-cluster-assembly-factor
MEEALKDSILGALEMVIDPELGIDIVNLGLVYKVNVDDEGVCTVDMTLTSMGCPMGPQIIDQVKTVLAEIPEIQDTEVNIVWSPPWTKDMMSRYAKIALGVS
>NZ_CP026064.1|WP_001182436.1|542133_542958_+|Cof-type-HAD-IIB-family-hydrolase
MQPHLICLDLDGTLLNDNKEISSYTKQVLNELQQRGHQIMIATGRPYRASQMYYHELNLTTPIVNFNGAYVHHPKDKNFKTCHEILDLGIAQNIIQGLQQYQVSNIIAEVKDYVFINNHDPRLFEGFSMGNPRIQTGNLLVHLKESPTSILIEAEESKIPEIKNMLTHFYADHIEHRRWGAPFPVIEIVKLGINKARGIEQVRQFLNIDRNNIIAFGDEDNDIEMIEYARHGVAMENGLQELKDVANNITFNNNEDGIGRYLNDFFNLNIRYYC
>NZ_CP026064.1|WP_001124516.1|543009_544326_+|CoA-disulfide-reductase
MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDTDMNQPILDELDKREIPYRLNEEIDAINGNEITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLTASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
>NZ_CP026064.1|WP_000902807.1|544496_544886_-|YisL-family-protein
MLHLHILSWVLAIILFIATYLNISKNQGGSPFFKPLHMILRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHTMFWITIALIIITMVLGVILPLGPISKLFGIG
>NZ_CP026064.1|WP_000670755.1|545210_546113_-|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>NZ_CP026064.1|WP_000154918.1|546276_549930_-|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKANDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGAEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTINGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVNYDESAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEVADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_CP026064.1|WP_000172374.1|549930_553407_-|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKQDPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFKQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFKQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEQILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>NZ_CP026064.1|WP_000711894.1|553566_554142_-|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYMIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>NZ_CP026064.1|WP_000758216.1|554157_554682_-|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDYDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>NZ_CP026064.1|WP_000007970.1|554686_555262_-|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRWVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTQPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE

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Crispr_ID: NZ_CP026064_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026064_2

1172475-1172612

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCCAACTTGCA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP026064_2

>merge|NZ_CP026064|2|1172475-1172612|CRISPRCasFinder
TTTATTTATGTCCCTCCCCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCA

>NZ_CP026064|2|2|1172475-1172612|CRISPRCasFinder
TTTATTTATGTCCCTCCCCAACTTGCA	CATTATTGTAAGCTGACTTTCCGCCAGCT
TCTATGTTGGGGCCCCGCCAACTTGCA	TTGCCTGTAGAATTTCTTTTCGAAATTC
TCTATGTTGGGGCCCCGCCAACTTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026064.1\|WP_000607067.1\|1178687_1179389_-\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NZ_CP026064.1\|WP_000570067.1\|1162267_1162927_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP026064.1\|WP_000163986.1\|1172733_1174170_-\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
NZ_CP026064.1\|WP_000062639.1\|1176055_1178347_-\|nitric-oxide-reductase	unknown	unknown	gnl\|CDD\|225795
NZ_CP026064.1\|WP_000925394.1\|1180680_1182420_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NZ_CP026064.1\|WP_000922316.1\|1175125_1175830_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP026064.1\|WP_001792906.1\|1179381_1179825_-\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NZ_CP026064.1\|WP_000337376.1\|1164251_1165244_-\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NZ_CP026064.1\|WP_000645456.1\|1179937_1180678_-\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
NZ_CP026064.1\|WP_001159765.1\|1166981_1167374_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000750483.1\|1169880_1170285_+\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NZ_CP026064.1\|WP_000029204.1\|1168984_1169866_+\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268
NZ_CP026064.1\|WP_000066927.1\|1174185_1174977_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225101
NZ_CP026064.1\|WP_000031266.1\|1171477_1172239_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP026064.1\|WP_000608837.1\|1182680_1183355_-\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_CP026064.1\|WP_000736787.1\|1162978_1163926_-\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|226451
NZ_CP026064.1\|WP_000182743.1\|1170312_1171227_+\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_CP026064.1\|WP_001066553.1\|1165477_1166854_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP026064.1\|WP_000757882.1\|1167754_1168753_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP026064.1\|WP_000975348.1\|1183498_1185220_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|376098

Protein	Function_ID	Function_description	E-value
NZ_CP026064.1\|WP_000607067.1\|1178687_1179389_-\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NZ_CP026064.1\|WP_000570067.1\|1162267_1162927_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	9.68709e-67
NZ_CP026064.1\|WP_000163986.1\|1172733_1174170_-\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
NZ_CP026064.1\|WP_000062639.1\|1176055_1178347_-\|nitric-oxide-reductase	gnl\|CDD\|225795	COG3256, NorB, Nitric oxide reductase large subunit [Inorganic ion transport and metabolism].	5.48419e-178
NZ_CP026064.1\|WP_000925394.1\|1180680_1182420_-\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NZ_CP026064.1\|WP_000922316.1\|1175125_1175830_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.13754e-62
NZ_CP026064.1\|WP_001792906.1\|1179381_1179825_-\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	8.44339e-64
NZ_CP026064.1\|WP_000337376.1\|1164251_1165244_-\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	6.16271e-152
NZ_CP026064.1\|WP_000645456.1\|1179937_1180678_-\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	4.37999e-152
NZ_CP026064.1\|WP_000750483.1\|1169880_1170285_+\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	4.08879e-70
NZ_CP026064.1\|WP_000029204.1\|1168984_1169866_+\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	4.46997e-117
NZ_CP026064.1\|WP_000066927.1\|1174185_1174977_-\|hypothetical-protein	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	8.99936e-55
NZ_CP026064.1\|WP_000031266.1\|1171477_1172239_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.23141e-27
NZ_CP026064.1\|WP_000608837.1\|1182680_1183355_-\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	1.30038e-153
NZ_CP026064.1\|WP_000736787.1\|1162978_1163926_-\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.47013e-32
NZ_CP026064.1\|WP_000182743.1\|1170312_1171227_+\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	7.32816e-143
NZ_CP026064.1\|WP_001066553.1\|1165477_1166854_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.58117e-30
NZ_CP026064.1\|WP_000757882.1\|1167754_1168753_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.32136e-100
NZ_CP026064.1\|WP_000975348.1\|1183498_1185220_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	3.18504e-35

>NZ_CP026064.1|WP_000031266.1|1171477_1172239_+|class-I-SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPIAIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYHQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTLKIINNALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKEH
>NZ_CP026064.1|WP_000182743.1|1170312_1171227_+|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKSHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>NZ_CP026064.1|WP_000750483.1|1169880_1170285_+|D-ribose-pyranase
MKKTAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>NZ_CP026064.1|WP_000029204.1|1168984_1169866_+|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>NZ_CP026064.1|WP_000757882.1|1167754_1168753_+|LacI-family-transcriptional-regulator
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMIVVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>NZ_CP026064.1|WP_001159765.1|1166981_1167374_-|hypothetical-protein
MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFGDTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLMLTDFQKENYNKYIQGQKQRVIFENGHFV
>NZ_CP026064.1|WP_001066553.1|1165477_1166854_+|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYMIIPKTVKS
>NZ_CP026064.1|WP_000337376.1|1164251_1165244_-|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKADAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGQSVEVSFKEGEVVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATANLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNEIVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>NZ_CP026064.1|WP_000736787.1|1162978_1163926_-|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSAQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATTGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNQAYNSHDGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPMSYLQSR
>NZ_CP026064.1|WP_000570067.1|1162267_1162927_+|ABC-transporter-ATP-binding-protein
MIEINNLSKRYRNKQIFNHLTMSFDSNRLTVLLGDNGAGKSTLLRMIAGIEKANDGTINYFGEKWNQRQIQNHIGYVPQDIALFEHMTVAENIKFFKSLCKNPINDTTINEYLQQLNFDDTSAKVSTLSGGNKRKINILVGLLGKPRILILDEPTVGIDLKSRHDIHQLLNIMKSKCLIILTTHHLDEVEALADDIKLIGQDPFYQHVLEDKQWTYTYY
>NZ_CP026064.1|WP_000163986.1|1172733_1174170_-|6-phospho-beta-glucosidase
MTKLPQNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDFGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKVHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYKQVIASNGDKL
>NZ_CP026064.1|WP_000066927.1|1174185_1174977_-|hypothetical-protein
MSNKYKDQAQDILTAVGGVENIVDVTYDTKGITIHMQHTIPSTANEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKDANVEEGANTDNINSQDTSYTPQAKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLISMIVPTKHAIGIRSEEGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>NZ_CP026064.1|WP_000922316.1|1175125_1175830_+|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHHSNFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEIATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDQLNSSEAALLQLSKGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>NZ_CP026064.1|WP_000062639.1|1176055_1178347_-|nitric-oxide-reductase
MSMQSSYKRLVKVLLTILVIVFSILLVGGWYIFKNEAPRPTKIVDQQGHTLVTKGELISGQAIYEKYGLTDYGSYLGNGSYLGPDYTAEALHHYLIGMRKYYAQDIYHKQLHKLNHAELAVVKDKVMKEIRINRYSEKEDQLVLTPGQVYGLKYLQDYYKKEFVNNPKQVGLNENMIKQFQNDDYMVAGNKVEHLSQFFFWGAWLSSTDRPGKTFSYTNNWPYDVDAGNTLPSAGILWTAISVTLLIAGLAFIIYIQKRYQFDMKPTYESERELPKIEVDRKITDSQRKVGKYLVVVMLLFLVQILLGELLAHYYVENKFFGIEIQRLFPFNIAKTWHVQLVIFWVATTWLAAGIYIVPKVLGKEPKKQGVLVDILFWALIIVVMGSMIGEWGHILGWIDSHWWLFGHFGWEYIELGKFWQILFIVGMVLWVIILCRGFLPAIRNKVQVNHDKRHLLTLLFVGAIAIPLFYLASLFIMPNSHVTFADYWRWWIVHLWVEGIFEAFAVVLIGFLMVNMKLTTIETTIRALYFQLILLLGTGIVGMGHHYYWQGDHSIWLALGSCFSALEVVPLCLLIWEAYTHYRLYKNSDIAFPYKGTFIFLASTGLWNAIGAGALGFLINTPAVNYFEHGTQWTAAHAHGSMAGVYGMFSIAIALYVFKNITKKEFWTPKVEKWIKISCWALNIGLAGMVFVTLMPVGYIQLKDALEHGYWHSRLTSFYEQPLVKAIMWGRMPWDIIFTVGVIILVVIFIRGYRHLKPKYRV
>NZ_CP026064.1|WP_000607067.1|1178687_1179389_-|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>NZ_CP026064.1|WP_001792906.1|1179381_1179825_-|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>NZ_CP026064.1|WP_000645456.1|1179937_1180678_-|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NZ_CP026064.1|WP_000925394.1|1180680_1182420_-|sensor-histidine-kinase
MLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>NZ_CP026064.1|WP_000608837.1|1182680_1183355_-|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAAVLEKKNVDLNELLQRLNEVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKATYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NZ_CP026064.1|WP_000975348.1|1183498_1185220_-|glycosyltransferase-family-2-protein
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLTVNANKQYRFNIMLEDIKADLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISMKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMVMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK

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Crispr_ID: NZ_CP026064_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026064_3

1614324-1614405

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP026064_3

>merge|NZ_CP026064|3|1614324-1614405|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP026064|3|3|1614324-1614405|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026064.1\|WP_014667759.1\|1615072_1615573_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000644427.1\|1608176_1609202_-\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191
NZ_CP026064.1\|WP_075583724.1\|1623506_1623995_+\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
NZ_CP026064.1\|WP_001789900.1\|1615770_1616340_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP026064.1\|WP_000751274.1\|1618412_1619114_+\|lytic-transglycosylase-IsaA	unknown	unknown	gnl\|CDD\|381607
NZ_CP026064.1\|WP_000697134.1\|1614622_1614853_-\|DUF896-domain-containing-protein	unknown	unknown	gnl\|CDD\|226677
NZ_CP026064.1\|WP_000706527.1\|1607065_1607956_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NZ_CP026064.1\|WP_000200684.1\|1616749_1617805_+\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP026064.1\|WP_001224183.1\|1611997_1612555_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP026064.1\|WP_000651839.1\|1613003_1613825_+\|NmrA/HSCARG-family-protein	unknown	unknown	gnl\|CDD\|187561
NZ_CP026064.1\|WP_000448903.1\|1609342_1610173_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP026064.1\|WP_000154459.1\|1619389_1619878_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP026064.1\|WP_000161828.1\|1611300_1612005_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187585
NZ_CP026064.1\|WP_000836420.1\|1610192_1611203_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|225070
NZ_CP026064.1\|WP_000616227.1\|1613841_1614219_+\|glyoxalase	unknown	unknown	gnl\|CDD\|226134
NZ_CP026064.1\|WP_000895186.1\|1605625_1606966_+\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
NZ_CP026064.1\|WP_001791985.1\|1616494_1616623_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000725226.1\|1622564_1623332_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP026064.1\|WP_000379833.1\|1620392_1622204_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP026064.1\|WP_000055844.1\|1612685_1612985_+\|DUF2316-family-protein	unknown	unknown	gnl\|CDD\|226806

Protein	Function_ID	Function_description	E-value
NZ_CP026064.1\|WP_000644427.1\|1608176_1609202_-\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.78714e-97
NZ_CP026064.1\|WP_001789900.1\|1615770_1616340_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.43347e-07
NZ_CP026064.1\|WP_000751274.1\|1618412_1619114_+\|lytic-transglycosylase-IsaA	gnl\|CDD\|381607	cd13925, RPF, core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.	2.63325e-06
NZ_CP026064.1\|WP_000697134.1\|1614622_1614853_-\|DUF896-domain-containing-protein	gnl\|CDD\|226677	COG4224, COG4224, Uncharacterized protein conserved in bacteria [Function unknown].	6.01061e-31
NZ_CP026064.1\|WP_000706527.1\|1607065_1607956_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	1.21918e-76
NZ_CP026064.1\|WP_000200684.1\|1616749_1617805_+\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.38046e-117
NZ_CP026064.1\|WP_001224183.1\|1611997_1612555_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.49706e-13
NZ_CP026064.1\|WP_000651839.1\|1613003_1613825_+\|NmrA/HSCARG-family-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.51828e-85
NZ_CP026064.1\|WP_000448903.1\|1609342_1610173_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.86854e-18
NZ_CP026064.1\|WP_000154459.1\|1619389_1619878_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.33488e-11
NZ_CP026064.1\|WP_000161828.1\|1611300_1612005_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.1238e-67
NZ_CP026064.1\|WP_000836420.1\|1610192_1611203_-\|amidohydrolase	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	2.02807e-77
NZ_CP026064.1\|WP_000616227.1\|1613841_1614219_+\|glyoxalase	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.48638e-58
NZ_CP026064.1\|WP_000895186.1\|1605625_1606966_+\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	5.10424e-93
NZ_CP026064.1\|WP_000725226.1\|1622564_1623332_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	9.90876e-31
NZ_CP026064.1\|WP_000379833.1\|1620392_1622204_+\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	3.4224e-84
NZ_CP026064.1\|WP_000055844.1\|1612685_1612985_+\|DUF2316-family-protein	gnl\|CDD\|226806	COG4367, COG4367, Uncharacterized protein conserved in bacteria [Function unknown].	1.97434e-38

>NZ_CP026064.1|WP_000616227.1|1613841_1614219_+|glyoxalase
MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIGQTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGTVVQEPTVSQGFYGAMFKDLDGHHFNFLVC
>NZ_CP026064.1|WP_000651839.1|1613003_1613825_+|NmrA/HSCARG-family-protein
MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIGHPHLSIVEGDLSDSDSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQHIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDERITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSEVTGKSTVIEGEFVSSVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQDYNK
>NZ_CP026064.1|WP_000055844.1|1612685_1612985_+|DUF2316-family-protein
MSLNKEQRRITAEELQAHFEASTLSVQMIAEKLNVTTEDVEKALAMKAPLGIFSHQLQRFIHLVWDVRNVINDNIKENGQTPEPYTYLKGEKEDYWFLR
>NZ_CP026064.1|WP_001224183.1|1611997_1612555_-|TetR/AcrR-family-transcriptional-regulator
MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSDYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFNFYYDLFKSDDDIYKKFKTDMLLQALSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
>NZ_CP026064.1|WP_000161828.1|1611300_1612005_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIDADGPTGTFINGDGEMPW
>NZ_CP026064.1|WP_000836420.1|1610192_1611203_-|amidohydrolase
MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTGFTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIAQYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKTAENLDVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSGIFDRYPKLNMIIGHWGEFIPFFLERMDEALFAEHLNHPVSYYFKNNFYITPSGMLTKPQFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSSNN
>NZ_CP026064.1|WP_000448903.1|1609342_1610173_-|alpha/beta-hydrolase
METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSEFEIRQYTHSDITLDDFTKYNDKITLLNGTDSRGSFPQDVNFYINNETGIPIVDIPGGHLGYIQKPEGFADVLLNMWS
>NZ_CP026064.1|WP_000644427.1|1608176_1609202_-|NADP-dependent-oxidoreductase
MKAIQIKKYNKNRDVQIRDITIPEIKSTEVLVKVAYAAINPLENLTINGSVKLIQNYKMPQTIGNELTGTIVKVGSKVEDYKLGDKIYSRLPIDRIGAFAEYVSIESNAIAKLPKNLNLKTGAAVPLTGLTAYQAITEELKAIPGKTLFIPGGSGSFGQMAVPIAKSLGLKVIVSGSPRLKDQFLAKGVDQYIDYKTENYCEVLSDIDYVIDTLGPNEFDKELSVMKPGGTIVSLINAPNKAFAVKNNFSPFKKLLFGLAGKKFDKKAQKKSIDYRFIFVRSDGEQLKILNKIIEQNNIIPDIDDHIFTIDEIDKALDYTFNHHTNGKVLIRIDNSDNTIY
>NZ_CP026064.1|WP_000706527.1|1607065_1607956_+|GTP-binding-protein
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVVDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTVTSDNKHESLHKTINHQFVQSPVKCTKAEFIKRLACLPSHIYRLKGFMTFEDTAHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
>NZ_CP026064.1|WP_000895186.1|1605625_1606966_+|ferrous-iron-transporter-B
MLEVKYDMRTGHYTPIPNEPHYLVISHADKLNATEKAKLRLLIIKQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPIGIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVVILISLSTAIIDQTGFKSWMIWAIEPSMLRIGLQGNDIVPLLEGFGCNAAAISQAAHQCHTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLKKNNQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPILNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLVFFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMLTSLSLVIGVGIIVKIVMLII
>NZ_CP026064.1|WP_000697134.1|1614622_1614853_-|DUF896-domain-containing-protein
MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLTTFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN
>NZ_CP026064.1|WP_014667759.1|1615072_1615573_-|hypothetical-protein
MTSIFVFAYLNNTSDNMLFRQQMIYACLLANVRHSSIVCLNNTCRIVDIRCLNTKIGGIDVSETDESQGFERTHNILNINQSSLGVVTYITNKLKSTLKQHIIIACGKKRIDYRLSYNFYTTYYDNVEIKKIDCEYTYAMPIAILIRHMMSFDNDYFFAQLRHPVL
>NZ_CP026064.1|WP_001789900.1|1615770_1616340_-|TetR/AcrR-family-transcriptional-regulator
MMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF
>NZ_CP026064.1|WP_001791985.1|1616494_1616623_+|hypothetical-protein
MDFKNEDKIKVYCNNMFEKLPISLSKNSEFCDILFFIVLSYR
>NZ_CP026064.1|WP_000200684.1|1616749_1617805_+|PTS-transporter-subunit-IIC
MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAWMITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKMITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSALVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADIIYRKVFRLYTNDIFKFMG
>NZ_CP026064.1|WP_000751274.1|1618412_1619114_+|lytic-transglycosylase-IsaA
MKKTIMASSLAVALGVTGYAASTGHEAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>NZ_CP026064.1|WP_000154459.1|1619389_1619878_+|GNAT-family-N-acetyltransferase
MTINIIEYNRSYKEELIEFILSIQKNEFNIKIDRDDQPDLENIEHNYLNSGGQFWLAINNHQNIVGTIGLIRLDNNMSALKKMFVDEGYRNLKIGKKLLDKVIMTCKEQNIDGIYLGTIDKFISAQYFYSNNGFREIKRGDLPSSFPKLDVDNRFYYRNLKG
>NZ_CP026064.1|WP_000379833.1|1620392_1622204_+|acetyltransferase
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYVIEIVLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>NZ_CP026064.1|WP_000725226.1|1622564_1623332_+|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWASAAASSGYTVNNTPKAGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>NZ_CP026064.1|WP_075583724.1|1623506_1623995_+|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKHIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRTELIHWISILPVIIFNKGPRLVKYINIFYAMITNVPIIIVQRYNRPRLTQLLRILKRRGERHD

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Crispr_ID: NZ_CP026064_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026064_4

1982620-1982744

Orphan

Consensus_repeat	Method
TGATATCAAGCGTTTTGTGAGCTTTCGAGTAAAGAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP026064_4

>merge|NZ_CP026064|4|1982620-1982744|CRISPRCasFinder
TGATATCAAGCGTTTTGTGAGCTTTCGAGTAAAGAGGATAATTTTCGAGTAACTCAAAAGAAAATACTAAAAAATCATGGGAAATCATTGATATCAAGGGTTTTGTGAGCTTTCGAGTAAAGAGG

>NZ_CP026064|4|4|1982620-1982744|CRISPRCasFinder
TGATATCAAGCGTTTTGTGAGCTTTCGAGTAAAGAGG	ATAATTTTCGAGTAACTCAAAAGAAAATACTAAAAAATCATGGGAAATCAT
TGATATCAAGGGTTTTGTGAGCTTTCGAGTAAAGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026064.1\|WP_000101625.1\|1975530_1975920_+\|30S-ribosomal-protein-S11	unknown	unknown	gnl\|CDD\|180007
NZ_CP026064.1\|WP_000170975.1\|1981822_1982221_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_CP026064.1\|WP_000389655.1\|1977861_1978671_+\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184207
NZ_CP026064.1\|WP_000569649.1\|1975994_1976939_+\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
NZ_CP026064.1\|WP_000769708.1\|1987099_1987525_-\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NZ_CP026064.1\|WP_001221857.1\|1980328_1981132_+\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP026064.1\|WP_000130134.1\|1984315_1985980_+\|acetolactate-synthase-AlsS	unknown	unknown	gnl\|CDD\|236312
NZ_CP026064.1\|WP_000044360.1\|1987819_1988635_+\|HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319792
NZ_CP026064.1\|WP_000155383.1\|1978667_1979528_+\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184205
NZ_CP026064.1\|WP_000655245.1\|1983638_1983821_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000174176.1\|1990393_1990672_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000791618.1\|1979517_1980324_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP026064.1\|WP_000136271.1\|1982809_1982989_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000179063.1\|1986016_1986721_+\|acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058
NZ_CP026064.1\|WP_000542274.1\|1976955_1977324_+\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
NZ_CP026064.1\|WP_001044438.1\|1991544_1992399_+\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|223810
NZ_CP026064.1\|WP_000090796.1\|1975141_1975507_+\|30S-ribosomal-protein-S13	unknown	unknown	gnl\|CDD\|235358
NZ_CP026064.1\|WP_001250036.1\|1981371_1981809_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP026064.1\|WP_103152883.1\|1988998_1990384_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340855
NZ_CP026064.1\|WP_000222252.1\|1992458_1994885_-\|polysaccharide-lyase-8-family-protein	unknown	unknown	gnl\|CDD\|238517

Protein	Function_ID	Function_description	E-value
NZ_CP026064.1\|WP_000101625.1\|1975530_1975920_+\|30S-ribosomal-protein-S11	gnl\|CDD\|180007	PRK05309, PRK05309, 30S ribosomal protein S11; Validated.	2.01588e-89
NZ_CP026064.1\|WP_000170975.1\|1981822_1982221_+\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.2295e-82
NZ_CP026064.1\|WP_000389655.1\|1977861_1978671_+\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184207	PRK13648, cbiO, cobalt transporter ATP-binding subunit; Provisional.	0
NZ_CP026064.1\|WP_000569649.1\|1975994_1976939_+\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	1.89947e-175
NZ_CP026064.1\|WP_000769708.1\|1987099_1987525_-\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	2.66977e-34
NZ_CP026064.1\|WP_001221857.1\|1980328_1981132_+\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	5.95917e-120
NZ_CP026064.1\|WP_000130134.1\|1984315_1985980_+\|acetolactate-synthase-AlsS	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
NZ_CP026064.1\|WP_000044360.1\|1987819_1988635_+\|HAD-IIB-family-hydrolase	gnl\|CDD\|319792	cd02605, HAD_SPP, sucrose-phosphatase, similar to Synechocystis sp PCC 6803 SPP. Sucrose-phosphatase (SPP; EC 3.1.3.24) catalyzes the dephosphorylation of sucrose-6(F)-phosphate (Suc6P)-the final step in the pathway of sucrose biosynthesis in plants and cyanobacteria. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.0464e-100
NZ_CP026064.1\|WP_000155383.1\|1978667_1979528_+\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
NZ_CP026064.1\|WP_000791618.1\|1979517_1980324_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.16976e-49
NZ_CP026064.1\|WP_000179063.1\|1986016_1986721_+\|acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	9.58959e-119
NZ_CP026064.1\|WP_000542274.1\|1976955_1977324_+\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	2.70058e-62
NZ_CP026064.1\|WP_001044438.1\|1991544_1992399_+\|M23-family-metallopeptidase	gnl\|CDD\|223810	COG0739, NlpD, Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane].	7.61272e-24
NZ_CP026064.1\|WP_000090796.1\|1975141_1975507_+\|30S-ribosomal-protein-S13	gnl\|CDD\|235358	PRK05179, rpsM, 30S ribosomal protein S13; Validated.	2.16257e-78
NZ_CP026064.1\|WP_001250036.1\|1981371_1981809_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.37368e-100
NZ_CP026064.1\|WP_103152883.1\|1988998_1990384_-\|glycosyltransferase	gnl\|CDD\|340855	cd04949, GT4_GtfA-like, accessory Sec system glycosyltransferase GtfA and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.	5.01392e-53
NZ_CP026064.1\|WP_000222252.1\|1992458_1994885_-\|polysaccharide-lyase-8-family-protein	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0

>NZ_CP026064.1|WP_000170975.1|1981822_1982221_+|30S-ribosomal-protein-S9
MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>NZ_CP026064.1|WP_001250036.1|1981371_1981809_+|50S-ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKATYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>NZ_CP026064.1|WP_001221857.1|1980328_1981132_+|tRNA-pseudouridine(38-40)-synthase-TruA
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRIHPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND
>NZ_CP026064.1|WP_000791618.1|1979517_1980324_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWVFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVQRTSYRQLKWQLRDTLSLIMIIPFAIILFVLKYSGV
>NZ_CP026064.1|WP_000155383.1|1978667_1979528_+|energy-coupling-factor-transporter-ATPase
MTIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKAIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKEKLADWHIGLPEIVQLQYDFEQKHQTKLKDIALTEEAFVSLYKEWQHEK
>NZ_CP026064.1|WP_000389655.1|1977861_1978671_+|energy-coupling-factor-transporter-ATPase
MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVKYDVAFGLENHAVPHDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTAIEIFDHAEELTTIGLDLPFPIKINQMLGYQTSFLTYEGLVDQL
>NZ_CP026064.1|WP_000542274.1|1976955_1977324_+|50S-ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
>NZ_CP026064.1|WP_000569649.1|1975994_1976939_+|DNA-directed-RNA-polymerase-subunit-alpha
MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
>NZ_CP026064.1|WP_000101625.1|1975530_1975920_+|30S-ribosomal-protein-S11
MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVTPVPHNGCRPPKRRRV
>NZ_CP026064.1|WP_000090796.1|1975141_1975507_+|30S-ribosomal-protein-S13
MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
>NZ_CP026064.1|WP_000136271.1|1982809_1982989_+|hypothetical-protein
MTEIVEFLSDGKLASRLEIQETMGLQKSYTSELIAELKKLEIIGSEGRGLGTRYYLIRD
>NZ_CP026064.1|WP_000655245.1|1983638_1983821_+|hypothetical-protein
MKDSIFWKKAFIPVYFIVAMLVFLLFRFYIKTDNFSMYLMIIFLICLGTASIIYNYKNNR
>NZ_CP026064.1|WP_000130134.1|1984315_1985980_+|acetolactate-synthase-AlsS
MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPAESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGLISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYDPIEYEASNWNKELDTQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISDKVDEPFINQQHLDELEQLRAHIDQETGIKATHEEGILHPVEIIESMQKVLTDETTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>NZ_CP026064.1|WP_000179063.1|1986016_1986721_+|acetolactate-decarboxylase
MASVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGSVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIHDEDFTNANIDYKDISDEIREAE
>NZ_CP026064.1|WP_000769708.1|1987099_1987525_-|MAP-domain-containing-protein
MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGYHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNELASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK
>NZ_CP026064.1|WP_000044360.1|1987819_1988635_+|HAD-IIB-family-hydrolase
MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDRRILEALVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
>NZ_CP026064.1|WP_103152883.1|1988998_1990384_-|glycosyltransferase
MTTYMLMYSIPEKAGGITSVMLNRSKLLAEKGYSCALLTLDDKNYDPLRAKLTNSGRLHKQVKIVNLYEELKMLYDVENTEIENKNMQTFEKLNLLNQEGFYIQKDEYEEKKYARYFKDNHYIMYKKWINGQLSHIDYFQNRKRFKRHVFQNKILRKEITFNDKNKMSEVKYLSNDGFCYLSYWYGDNENIVNIFYFDKNSKEVLNFKNNKAFHSYWLDKNLTSNDVLILDGIGTYHKVENMQNNDIKKIFTIHTNHFMSPYSYGAEIKPEFRNMLLNLKKLDTLVVLTKEQKDDIIKQFGDYNNIKVIPNAISFEENLTQNIREKNSIIVLQRFVAMKNITHIISAINIVRKKVKDVKLHIYGTGTQKENYTKLIKKLKLQDNVFIHDYAFDIRALYTKTSLSVLTSDYEGLPMSLLEAMSYGVPVISYPINYGPKSIIQNNINGIITKKKDNINELAKK
>NZ_CP026064.1|WP_000174176.1|1990393_1990672_-|hypothetical-protein
MTLNEYNYNNELILKLNKIEVQKNNEKISEVFKDYEILKPKIVFNGSNPYLALNHIIVAEIENYSSLETFSKIYVDEDYYYNYGELIIKCKK
>NZ_CP026064.1|WP_001044438.1|1991544_1992399_+|M23-family-metallopeptidase
MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWHFRKLFKSYTRQSDVHELKVCTQNDGTMEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKNKGKVNTDYFYFGKDIIAPANGTVEKVANGVQDNSIGSTNESQFLGNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGDVVCGLQGE
>NZ_CP026064.1|WP_000222252.1|1992458_1994885_-|polysaccharide-lyase-8-family-protein
MTYRMKKWQKISTITLLMAGVITFNDSEFRSVDKHQIAVADTNVQTTDYEKLRNTWLNVNYGYNQYDENNDAMKKKFEATEKEATNLLSSMKTESDRKYLWENSKDLDTKSADMTRTYRNIEKIAEAMKHKNTKLNTPDNKNKVKDALEWLHKNAYGKEPTDKVKELTENFKNKTSRNTNLNWWDYEIGTPRALTNTLILLNGDISSDEKKKYTAPIKTFAPESDKILSSVGQPEQAKGGNLVDIAKVKLLESIIEEDTTMMKESIDAFNKVFTYVQSNATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETSFKDSNQNDTTLKSWIDEGFMPLIYKGEMMDLSRGRAISRENETSHSVSATVMKSLLRLSDAMDDSTKAKYKQIVKTSVKSDSSYKQNDYLSSYSDISKMKSLMEDSTISTNDLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINNENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTIENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKTNGYTLYTDDKQTTASDNQDTNSVFLESTNKPKNNIGYHFLNKSKITVKKESHTGKWSDINKSQKSEDKTDEYYEVTQKHSDKDNKYGYVLYPGITKDNFKSKASQVTVVKQDDDFHVVKDNESVWAGVNYSDSAKTFEINGTKVEVKAKGMFILKKKNDKTYECSFYNPESTNPASDIESKISMTGYSITNKDTSTTNESGVRFELTK

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Crispr_ID: NZ_CP026064_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026064_5

2062947-2063050

Orphan

Consensus_repeat	Method
CGCATCAACTGCATAAGAGCCCCTAACAACTAAAGTTG	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP026064_5

>merge|NZ_CP026064|5|2062947-2063050|CRISPRCasFinder
CGCATCAACTGCATAAGAGCCCCTAACAACTAAAGTTGAAAAATAGAGGAATACAGTTGGATGCTACGCATCAACTGCATAAGAGCCCCTAACAACTAAAGTTG

>NZ_CP026064|5|5|2062947-2063050|CRISPRCasFinder
CGCATCAACTGCATAAGAGCCCCTAACAACTAAAGTTG	AAAAATAGAGGAATACAGTTGGATGCTA
CGCATCAACTGCATAAGAGCCCCTAACAACTAAAGTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026064.1\|WP_000070865.1\|2071293_2071737_+\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP026064.1\|WP_075583739.1\|2062447_2062552_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000334463.1\|2057208_2059014_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP026064.1\|WP_000003755.1\|2065405_2065726_-\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP026064.1\|WP_024928151.1\|2061612_2061771_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_001292149.1\|2052376_2052811_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP026064.1\|WP_047230659.1\|2043635_2050952_+\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089
NZ_CP026064.1\|WP_001024097.1\|2065877_2066543_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP026064.1\|WP_000495678.1\|2063066_2064158_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000927368.1\|2052822_2054955_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP026064.1\|WP_000370944.1\|2060095_2060953_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP026064.1\|WP_001123311.1\|2070680_2071094_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP026064.1\|WP_000808817.1\|2067947_2068178_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000083799.1\|2054989_2056528_-\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP026064.1\|WP_000123402.1\|2068851_2070225_+\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP026064.1\|WP_001127960.1\|2066978_2067917_+\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP026064.1\|WP_000019744.1\|2064423_2065404_-\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP026064.1\|WP_000648731.1\|2051270_2052377_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP026064.1\|WP_000160303.1\|2071858_2072569_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP026064.1\|WP_000908181.1\|2059245_2060028_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044

Protein	Function_ID	Function_description	E-value
NZ_CP026064.1\|WP_000070865.1\|2071293_2071737_+\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.87929e-68
NZ_CP026064.1\|WP_001123311.1\|2070680_2071094_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.44732e-45
NZ_CP026064.1\|WP_000334463.1\|2057208_2059014_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP026064.1\|WP_001292149.1\|2052376_2052811_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP026064.1\|WP_000160303.1\|2071858_2072569_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	1.82405e-156
NZ_CP026064.1\|WP_000003755.1\|2065405_2065726_-\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.83702e-17
NZ_CP026064.1\|WP_047230659.1\|2043635_2050952_+\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	5.17576e-109
NZ_CP026064.1\|WP_001024097.1\|2065877_2066543_+\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	9.50195e-47
NZ_CP026064.1\|WP_000927368.1\|2052822_2054955_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.54719e-67
NZ_CP026064.1\|WP_000370944.1\|2060095_2060953_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.32332e-59
NZ_CP026064.1\|WP_000083799.1\|2054989_2056528_-\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP026064.1\|WP_000123402.1\|2068851_2070225_+\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_CP026064.1\|WP_001127960.1\|2066978_2067917_+\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP026064.1\|WP_000908181.1\|2059245_2060028_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	2.15146e-106
NZ_CP026064.1\|WP_000648731.1\|2051270_2052377_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP026064.1\|WP_000019744.1\|2064423_2065404_-\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108

>NZ_CP026064.1|WP_075583739.1|2062447_2062552_+|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK
>NZ_CP026064.1|WP_024928151.1|2061612_2061771_-|hypothetical-protein
MRKSSDALFNLLTQSFELIEGVHNELVTDNLKTVMYKPRKERTNGRINRRFK
>NZ_CP026064.1|WP_000370944.1|2060095_2060953_+|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQDETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP026064.1|WP_000908181.1|2059245_2060028_+|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGEMPGKVGYSAETVRQHIGFVSHSLLEKFQDGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP026064.1|WP_000334463.1|2057208_2059014_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP026064.1|WP_000083799.1|2054989_2056528_-|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPIMKFIMHILSVAVESLVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVATLIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP026064.1|WP_000927368.1|2052822_2054955_-|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVESYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQLQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLDQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDTPYLMVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMNDKDDVHVETKDIDGNTSFENEQTSNLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRSKFLERIKKQFI
>NZ_CP026064.1|WP_001292149.1|2052376_2052811_-|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP026064.1|WP_000648731.1|2051270_2052377_-|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFASFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTGDQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP026064.1|WP_047230659.1|2043635_2050952_+|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISINPTTASAAEQNQPAQNQPAQPADPNAQPNANAGAQANPTAQPAAPANQGGQADPAANQGGQANPAGGAVQPAAGTTQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANAPAGAQPAAAVAANGQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQARGNVAALGRVNANDSTDHGNFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQDVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQTANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNIANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDAKAQEKITAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTAQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSTASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTAPATTAKAEALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEIFKIENITDSTQTKMDAYKEVKQAATARKAQNATVSNATDEEVAEANAAVDAAQTEGLHDIQVVKSQQEVADTKAKVLDKINAIQTQSRVKPAADTEVDNAYNTRKQEIQNSNASTTEEKEAAYTELDAKKQEARTNLDAANTNSAVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTSEEQQAAKDKVDQAVVTANADIDNAAANSDVDNAKTTNEATIAAITPDANVKPQAKQAIADKVQAQETAIDANNGAITEEKAAAKQQVQTEKTTADTAIDGAHSNAEVEAAKNAEIAKIEAIQPATTTKDNAKQAIATKANERKTAIAQTQDITAEEIAAANADVDNAVIQANSNIEAANSQNDVDQAKTTGETSIDQVTPTVNKKATARNEITTTLNNKLQEIQATPDATDEEKQDAETEANTENAKANQAITAATTNAEVDEAKTNAEAAINAVTPKVMKKQAAKDEIDQLQAAQTAVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDNNGVDTAKDAGKNSIQSTQPATAVKSNAKNDVDQAVTTQNQAIDNTTGATTEEKNAAKDLVSKAKEKAYQDILNAQTTNDVTQLKDQAVADIQGITADTTIKDVAKGELTAKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAVQAIDPIQASTDVKTNARAELLNEMQNKITEILNDNTTTNEEKGKDIGPVRAAYEEGLNNINVANSTGDVTTAKDAAVQKVQQLHANPVKKPAGKTELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNIDQSSTDDYVDAAVRDGKAKINAVKTFSEYKKDALAKIADAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALESINNGVDNSDVDDALTQGKATIDAVQVDATVKAKANQAIDAKAQETKESIDQSDQLTAEEKTEALATIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDSDATTEEKEVFTNALEEILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPEVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADDLDKTQTNAEVAELQNVTIPAIEAIVPQNDPDANHSSSDNNDATANTNVNAEPDNAGQPNVTESTDNANADTSSTTTNNHNDAATGETTATSTNNSSTDDANDKPTANNNSSVDASIDNSATGNGTTDKPATTESTEKTSSADSKDNASVNDSNQNAEVNNSAESQPTNGKVAQPKSENKAKVEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTSNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTEDSQKADMATADTKDNQASIGSSADANNKATQNDGANASPATVSNGSNSANQDMLNVTKPEENKANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE
>NZ_CP026064.1|WP_000495678.1|2063066_2064158_-|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAILLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENDKVATSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP026064.1|WP_000019744.1|2064423_2065404_-|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP026064.1|WP_000003755.1|2065405_2065726_-|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEIHTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP026064.1|WP_001024097.1|2065877_2066543_+|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNYQEFQIISGEQDIKDALTQFEIEKD
>NZ_CP026064.1|WP_001127960.1|2066978_2067917_+|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP026064.1|WP_000808817.1|2067947_2068178_+|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP026064.1|WP_000123402.1|2068851_2070225_+|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP026064.1|WP_001123311.1|2070680_2071094_+|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYRFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP026064.1|WP_000070865.1|2071293_2071737_+|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP026064.1|WP_000160303.1|2071858_2072569_-|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNAAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE

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Crispr_ID: NZ_CP026064_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026064_6

2309882-2309971

Orphan

Consensus_repeat	Method
AAAAGAAATTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP026064_6

>merge|NZ_CP026064|6|2309882-2309971|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGGG

>NZ_CP026064|6|6|2309882-2309971|CRISPRCasFinder
AAAAGAAATTCTACAGGCAATGCAAGTTGGGG	TGTGGGCCCCAACACAGAGAATTTCG
AAAAGAAATTCTACAGGCAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026064.1\|WP_000636142.1\|2310104_2310863_+\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP026064.1\|WP_000999713.1\|2308589_2309576_-\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP026064.1\|WP_000140172.1\|2302600_2303671_+\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP026064.1\|WP_000613738.1\|2303738_2304293_-\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP026064.1\|WP_000544969.1\|2306789_2307521_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP026064.1\|WP_001670387.1\|2307745_2308159_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_000149064.1\|2311480_2312182_+\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NZ_CP026064.1\|WP_000153535.1\|2313211_2313841_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP026064.1\|WP_001017131.1\|2312178_2313222_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP026064.1\|WP_000548775.1\|2301823_2302354_+\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_CP026064.1\|WP_075583716.1\|2316544_2317801_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_CP026064.1\|WP_000180460.1\|2316341_2316542_+\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177
NZ_CP026064.1\|WP_000428172.1\|2315448_2315724_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_001110179.1\|2311079_2311466_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_001790257.1\|2307606_2307717_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026064.1\|WP_001250329.1\|2305474_2306788_+\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_CP026064.1\|WP_000228666.1\|2315730_2316195_-\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP026064.1\|WP_000037075.1\|2313953_2315171_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP026064.1\|WP_000949467.1\|2304682_2305183_-\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_CP026064.1\|WP_001790679.1\|2304508_2304601_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP026064.1\|WP_000636142.1\|2310104_2310863_+\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
NZ_CP026064.1\|WP_000999713.1\|2308589_2309576_-\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
NZ_CP026064.1\|WP_000140172.1\|2302600_2303671_+\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP026064.1\|WP_000613738.1\|2303738_2304293_-\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
NZ_CP026064.1\|WP_000544969.1\|2306789_2307521_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
NZ_CP026064.1\|WP_000548775.1\|2301823_2302354_+\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.92343e-11
NZ_CP026064.1\|WP_000149064.1\|2311480_2312182_+\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
NZ_CP026064.1\|WP_000153535.1\|2313211_2313841_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.75115e-79
NZ_CP026064.1\|WP_001017131.1\|2312178_2313222_+\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
NZ_CP026064.1\|WP_075583716.1\|2316544_2317801_+\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_CP026064.1\|WP_000180460.1\|2316341_2316542_+\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
NZ_CP026064.1\|WP_001250329.1\|2305474_2306788_+\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.37755e-99
NZ_CP026064.1\|WP_000228666.1\|2315730_2316195_-\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NZ_CP026064.1\|WP_000037075.1\|2313953_2315171_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
NZ_CP026064.1\|WP_000949467.1\|2304682_2305183_-\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74

>NZ_CP026064.1|WP_000999713.1|2308589_2309576_-|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>NZ_CP026064.1|WP_001670387.1|2307745_2308159_+|hypothetical-protein
MKPTKVILRDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>NZ_CP026064.1|WP_001790257.1|2307606_2307717_+|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_CP026064.1|WP_000544969.1|2306789_2307521_+|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>NZ_CP026064.1|WP_001250329.1|2305474_2306788_+|Mur-ligase-family-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_CP026064.1|WP_000949467.1|2304682_2305183_-|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_CP026064.1|WP_001790679.1|2304508_2304601_+|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP026064.1|WP_000613738.1|2303738_2304293_-|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP026064.1|WP_000140172.1|2302600_2303671_+|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP026064.1|WP_000548775.1|2301823_2302354_+|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLFLLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>NZ_CP026064.1|WP_000636142.1|2310104_2310863_+|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NZ_CP026064.1|WP_001110179.1|2311079_2311466_+|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NZ_CP026064.1|WP_000149064.1|2311480_2312182_+|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NZ_CP026064.1|WP_001017131.1|2312178_2313222_+|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NZ_CP026064.1|WP_000153535.1|2313211_2313841_+|response-regulator-transcription-factor
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NZ_CP026064.1|WP_000037075.1|2313953_2315171_-|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NZ_CP026064.1|WP_000428172.1|2315448_2315724_-|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NZ_CP026064.1|WP_000228666.1|2315730_2316195_-|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NZ_CP026064.1|WP_000180460.1|2316341_2316542_+|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>NZ_CP026064.1|WP_075583716.1|2316544_2317801_+|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHELKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGETVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	441863-441891	0	1.0
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	644735-644763	0	1.0
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	1172613-1172641	0	1.0
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	1776107-1776135	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	37064-37091	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	125809-125836	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	415889-415916	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	653715-653742	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	823715-823742	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	1056395-1056422	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	1614394-1614421	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	1956415-1956442	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	2308472-2308499	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	2415032-2415059	0	1.0
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	2629531-2629558	0	1.0
NZ_CP026064_6	6.1\|2309914\|26\|NZ_CP026064\|CRISPRCasFinder	2309914-2309939	26	NZ_CP026064.1	653697-653722	0	1.0
NZ_CP026064_6	6.1\|2309914\|26\|NZ_CP026064\|CRISPRCasFinder	2309914-2309939	26	NZ_CP026064.1	1956397-1956422	0	1.0
NZ_CP026064_6	6.1\|2309914\|26\|NZ_CP026064\|CRISPRCasFinder	2309914-2309939	26	NZ_CP026064.1	2308454-2308479	0	1.0
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	2107610-2107638	1	0.966
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	823657-823684	1	0.964
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	1096488-1096515	1	0.964
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	37006-37034	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	125750-125778	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	339691-339719	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	415831-415859	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	823602-823630	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	1096543-1096571	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	2309814-2309842	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	2614998-2615026	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	2629473-2629501	2	0.931
NZ_CP026064_2	2.1\|1172502\|29\|NZ_CP026064\|CRISPRCasFinder	1172502-1172530	29	NZ_CP026064.1	2629586-2629614	2	0.931
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	339634-339661	2	0.929
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	541565-541592	2	0.929
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	1497530-1497557	2	0.929
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	1945607-1945634	2	0.929
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	2299006-2299033	2	0.929
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	2299122-2299149	2	0.929
NZ_CP026064_2	2.2\|1172558\|28\|NZ_CP026064\|CRISPRCasFinder	1172558-1172585	28	NZ_CP026064.1	2510038-2510065	2	0.929
NZ_CP026064_3	3.1\|1614348\|34\|NZ_CP026064\|CRISPRCasFinder	1614348-1614381	34	NZ_CP026064.1	441904-441937	2	0.941

1. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 441863-441891, mismatch: 0, identity: 1.0

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgactttccgccagct	Protospacer
*****************************

2. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 644735-644763, mismatch: 0, identity: 1.0

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgactttccgccagct	Protospacer
*****************************

3. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 1172613-1172641, mismatch: 0, identity: 1.0

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgactttccgccagct	Protospacer
*****************************

4. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 1776107-1776135, mismatch: 0, identity: 1.0

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgactttccgccagct	Protospacer
*****************************

5. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 37064-37091, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

6. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 125809-125836, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

7. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 415889-415916, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

8. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 653715-653742, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

9. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 823715-823742, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

10. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 1056395-1056422, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

11. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 1614394-1614421, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

12. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 1956415-1956442, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

13. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 2308472-2308499, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

14. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 2415032-2415059, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

15. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 2629531-2629558, mismatch: 0, identity: 1.0

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttcttttcgaaattc	Protospacer
****************************

16. spacer 6.1|2309914|26|NZ_CP026064|CRISPRCasFinder matches to position: 653697-653722, mismatch: 0, identity: 1.0

tgtgggccccaacacagagaatttcg	CRISPR spacer
tgtgggccccaacacagagaatttcg	Protospacer
**************************

17. spacer 6.1|2309914|26|NZ_CP026064|CRISPRCasFinder matches to position: 1956397-1956422, mismatch: 0, identity: 1.0

tgtgggccccaacacagagaatttcg	CRISPR spacer
tgtgggccccaacacagagaatttcg	Protospacer
**************************

18. spacer 6.1|2309914|26|NZ_CP026064|CRISPRCasFinder matches to position: 2308454-2308479, mismatch: 0, identity: 1.0

tgtgggccccaacacagagaatttcg	CRISPR spacer
tgtgggccccaacacagagaatttcg	Protospacer
**************************

19. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 2107610-2107638, mismatch: 1, identity: 0.966

cattattgtaagctgactttccgccagct	CRISPR spacer
cattaatgtaagctgactttccgccagct	Protospacer
***** ***********************

20. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 823657-823684, mismatch: 1, identity: 0.964

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcctgtagaatttctttttgaaattc	Protospacer
********************.*******

21. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 1096488-1096515, mismatch: 1, identity: 0.964

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcttgtagaatttcttttcgaaattc	Protospacer
****.***********************

22. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 37006-37034, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgacttttcgtcagct	Protospacer
********************.**.*****

23. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 125750-125778, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgacttttcgtcagct	Protospacer
********************.**.*****

24. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 339691-339719, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgacttttcgtcagct	Protospacer
********************.**.*****

25. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 415831-415859, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgacttttcgtcagct	Protospacer
********************.**.*****

26. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 823602-823630, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgtcttttcgccagct	Protospacer
*************** ****.********

27. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 1096543-1096571, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgacttttcgtcagct	Protospacer
********************.**.*****

28. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 2309814-2309842, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgacttttcgtcagct	Protospacer
********************.**.*****

29. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 2614998-2615026, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgtcttttcgccagct	Protospacer
*************** ****.********

30. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 2629473-2629501, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgacttttcgtcagct	Protospacer
********************.**.*****

31. spacer 2.1|1172502|29|NZ_CP026064|CRISPRCasFinder matches to position: 2629586-2629614, mismatch: 2, identity: 0.931

cattattgtaagctgactttccgccagct	CRISPR spacer
cattattgtaagctgacttttcgtcagct	Protospacer
********************.**.*****

32. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 339634-339661, mismatch: 2, identity: 0.929

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgtctgtagaatttctttttgaaattc	Protospacer
***.****************.*******

33. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 541565-541592, mismatch: 2, identity: 0.929

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgcttgtagaatttctttttgaaattc	Protospacer
****.***************.*******

34. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 1497530-1497557, mismatch: 2, identity: 0.929

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgtttgtagaatttcttttcgaaattc	Protospacer
***..***********************

35. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 1945607-1945634, mismatch: 2, identity: 0.929

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgtctgtagaatttctttttgaaattc	Protospacer
***.****************.*******

36. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 2299006-2299033, mismatch: 2, identity: 0.929

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgtctgtagaatttcctttcgaaattc	Protospacer
***.************.***********

37. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 2299122-2299149, mismatch: 2, identity: 0.929

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgtctgtagaatttcctttcgaaattc	Protospacer
***.************.***********

38. spacer 2.2|1172558|28|NZ_CP026064|CRISPRCasFinder matches to position: 2510038-2510065, mismatch: 2, identity: 0.929

ttgcctgtagaatttcttttcgaaattc	CRISPR spacer
ttgtttgtagaatttcttttcgaaattc	Protospacer
***..***********************

39. spacer 3.1|1614348|34|NZ_CP026064|CRISPRCasFinder matches to position: 441904-441937, mismatch: 2, identity: 0.941

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attggaaatccaattcctctttgttggggcccat	Protospacer
*****.*********.******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

162875 : 171951

Staphylococcus_phage(62.5%)

capsid,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000285524.1\|162875_164162_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.4e-28	28.7
WP_000906223.1\|164719_164968_-	hypothetical protein	NA	NA	NA	NA
WP_001120900.1\|165088_165460_-	hypothetical protein	NA	NA	NA	NA
WP_001215400.1\|165593_166829_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1
WP_001095317.1\|166840_167608_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
WP_024928116.1\|167587_167875_-\|capsid	minor capsid protein	A0A1W6JNH6	Staphylococcus_phage	2.5e-18	71.7
WP_000956747.1\|167920_168172_-	hypothetical protein	NA	NA	NA	NA
WP_001791646.1\|168172_168346_-	hypothetical protein	NA	NA	NA	NA
WP_000477492.1\|168300_168405_-	hypothetical protein	NA	NA	NA	NA
WP_000006110.1\|168916_169102_-	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
WP_001788716.1\|169529_169640_-	hypothetical protein	NA	NA	NA	NA
WP_001002340.1\|170340_170547_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
WP_001789892.1\|170840_171065_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.3e-18	71.0
WP_001789891.1\|171753_171951_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4

DBSCAN-SWA_2

432109 : 440582

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000238674.1\|432109_432676_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.5e-30	40.7
WP_000030811.1\|432678_433707_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_000483706.1\|433699_435184_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000032745.1\|435162_437352_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.6e-141	39.8
WP_000666805.1\|437344_438016_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000848350.1\|438017_438281_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000174042.1\|438280_438985_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	6.2e-47	41.6
WP_001010399.1\|438988_440113_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_001670307.1\|440099_440582_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	4.0e-21	44.0

DBSCAN-SWA_3

460293 : 486880

Lactococcus_phage(40.0%)

bacteriocin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001089094.1\|460293_461475_+\|protease	cysteine protease staphopain B	NA	NA	NA	NA
WP_000284457.1\|461512_461842_+	staphostatin B	NA	NA	NA	NA
WP_000184947.1\|462079_462901_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_000150210.1\|462893_463697_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_000526685.1\|463683_465357_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_075583703.1\|465343_466555_-	isochorismate synthase	NA	NA	NA	NA
WP_072357920.1\|466658_466736_-	hypothetical protein	NA	NA	NA	NA
WP_000070966.1\|466886_467825_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000620948.1\|467876_468428_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_075583698.1\|468517_468808_+	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	5.7e-07	38.0
WP_075583699.1\|468871_469003_+	hypothetical protein	NA	NA	NA	NA
WP_000766009.1\|470496_470853_+	DoxX family protein	NA	NA	NA	NA
WP_001792054.1\|470941_471079_-	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
WP_014667689.1\|471219_471510_+	hypothetical protein	NA	NA	NA	NA
WP_001095317.1\|471953_472721_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	6.3e-53	44.6
WP_001215400.1\|472732_473968_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	3.3e-104	49.1
WP_000571189.1\|474085_474442_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	5.0e-05	40.3
WP_000668623.1\|474438_474759_-	YxeA family protein	NA	NA	NA	NA
WP_000870799.1\|474761_476726_-\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_075583734.1\|476769_477042_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_001033867.1\|477985_478588_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000214898.1\|478602_478779_-	YkvS family protein	NA	NA	NA	NA
WP_000668821.1\|478977_479964_+	lipoate--protein ligase	NA	NA	NA	NA
WP_000876826.1\|480044_480263_-	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000287265.1\|480472_481042_+	competence protein ComK	NA	NA	NA	NA
WP_000414178.1\|481530_483042_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000021865.1\|483180_484539_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_075583733.1\|484555_486880_-\|protease	trypsin-like serine protease	W5SAB9	Pithovirus	2.8e-11	27.4

DBSCAN-SWA_4

689093 : 701360

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000876310.1\|689093_690065_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	7.8e-141	80.2
WP_000562498.1\|690434_691406_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000855510.1\|691525_693631_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
WP_000692521.1\|693593_693992_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_001068489.1\|694792_695659_+	DMT family transporter	NA	NA	NA	NA
WP_000930014.1\|695678_696179_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_000193751.1\|696516_698022_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_031789463.1\|698099_698201_-	hypothetical protein	NA	NA	NA	NA
WP_000429021.1\|698291_699209_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	6.2e-07	22.4
WP_000197261.1\|699601_700144_-	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000663028.1\|700304_701360_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.8e-21	26.4

DBSCAN-SWA_5

713333 : 721154

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217795.1\|713333_714485_-	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	1.2e-23	36.1
WP_000604513.1\|714468_715062_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.7e-37	42.4
WP_000446724.1\|715412_716081_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000941336.1\|716082_716502_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_001062973.1\|716505_717219_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	9.3e-51	42.7
WP_000637680.1\|717317_717902_+	hypothetical protein	NA	NA	NA	NA
WP_001093556.1\|718181_718622_+	DM13 domain-containing protein	NA	NA	NA	NA
WP_001037805.1\|718964_719438_+	DoxX family protein	NA	NA	NA	NA
WP_000149344.1\|719412_720099_+	response regulator transcription factor	NA	NA	NA	NA
WP_000244413.1\|720098_721154_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8

DBSCAN-SWA_6

1034566 : 1051535

Staphylococcus_phage(40.0%)

capsid,terminase,integrase

attL 1026264:1026282|attR 1054573:1054591

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1026264:1026282	attL	NA	NA	NA	NA
WP_000746599.1\|1034566_1035289_+	exotoxin	A0A1X9H080	Staphylococcus_phage	2.1e-26	34.9
WP_001670267.1\|1035455_1036256_-	exotoxin	A0A097PAT7	Streptococcus_pyogenes_phage	4.0e-50	43.4
WP_001035624.1\|1037039_1037594_+	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	1.2e-58	66.7
WP_001670266.1\|1037804_1038944_-	FRG domain-containing protein	NA	NA	NA	NA
WP_031789455.1\|1038930_1039524_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_088124083.1\|1039701_1039857_-\|terminase	terminase	Q4ZE85	Staphylococcus_phage	2.2e-21	96.0
WP_000253083.1\|1039853_1040345_-	hypothetical protein	A0A2H4JB26	uncultured_Caudovirales_phage	3.0e-24	39.9
WP_000657544.1\|1040527_1041586_-\|capsid	phage capsid protein	A0A0K2CZ99	Paenibacillus_phage	3.6e-14	26.6
WP_000884055.1\|1041572_1041779_-	hypothetical protein	NA	NA	NA	NA
WP_001081426.1\|1042003_1042348_-	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	5.5e-41	65.2
WP_001670264.1\|1043007_1045371_-	phage/plasmid primase P4 family domain-containing protein	A0A2H4JCU9	uncultured_Caudovirales_phage	7.5e-137	39.3
WP_001103961.1\|1045462_1045762_-	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	5.9e-31	66.7
WP_001058502.1\|1045762_1045987_-	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	1.5e-15	61.8
WP_001670263.1\|1045979_1046126_-	hypothetical protein	NA	NA	NA	NA
WP_000080596.1\|1046172_1046433_-	hypothetical protein	NA	NA	NA	NA
WP_001670262.1\|1046433_1046670_-	helix-turn-helix transcriptional regulator	Q38329	Lactococcus_phage	3.2e-08	40.0
WP_001670261.1\|1046802_1047189_+	helix-turn-helix transcriptional regulator	U3PIS7	Lactobacillus_phage	3.8e-06	41.2
WP_001670260.1\|1047272_1048409_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	1.3e-75	42.5
WP_000424969.1\|1048502_1050044_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	32.6
WP_000264071.1\|1050068_1051535_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
1054573:1054591	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2187638 : 2263319

Staphylococcus_phage(92.21%)

holin,portal,integrase,capsid,terminase,tail,head,protease

attL 2202716:2202733|attR 2271061:2271078

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000197645.1\|2187638_2188382_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000917289.1\|2188558_2188843_+	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
WP_000240649.1\|2188918_2190535_+	chaperonin GroEL	A0A240F779	uncultured_virus	5.8e-157	54.7
WP_000128898.1\|2191236_2191449_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-23	74.3
WP_001293059.1\|2191445_2192036_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.2e-96	94.7
WP_075583719.1\|2192353_2192791_+	hypothetical protein	NA	NA	NA	NA
WP_000022887.1\|2192896_2193340_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001045063.1\|2194182_2195490_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_047230661.1\|2195650_2196562_+	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001789591.1\|2196623_2197415_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000206641.1\|2197839_2199063_-	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_000791416.1\|2199497_2200550_+	bi-component leukocidin LukGH subunit H	A0A2I6PDF3	Staphylococcus_phage	1.3e-35	32.1
WP_000595402.1\|2200571_2201588_+	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	3.9e-26	29.3
WP_000857198.1\|2202706_2203744_-\|integrase	site-specific integrase	A0A1X9H022	Staphylococcus_phage	2.6e-179	100.0
2202716:2202733	attL	NA	NA	NA	NA
WP_001549185.1\|2203934_2204648_-	toxin MazF	A0A1X9H026	Staphylococcus_phage	5.0e-129	100.0
WP_000705236.1\|2204725_2204908_-	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	3.4e-26	98.3
WP_000109189.1\|2204978_2205164_-	hypothetical protein	U5U7D6	Staphylococcus_phage	2.3e-25	100.0
WP_000345949.1\|2205160_2205307_-	hypothetical protein	A0A1X9H032	Staphylococcus_phage	3.3e-19	100.0
WP_001557601.1\|2205380_2206235_-	restriction endonuclease	A0A1X9H037	Staphylococcus_phage	7.3e-151	100.0
WP_001083975.1\|2206246_2206963_-	helix-turn-helix domain-containing protein	A0A1X9H038	Staphylococcus_phage	5.4e-131	100.0
WP_000639923.1\|2207126_2207369_+	DUF739 family protein	A0A1X9H035	Staphylococcus_phage	1.6e-39	100.0
WP_000435349.1\|2207381_2207828_+	hypothetical protein	A0A1W6JPI3	Staphylococcus_phage	1.9e-78	100.0
WP_000939495.1\|2207842_2207983_+	hypothetical protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
WP_000772137.1\|2207975_2208185_-	hypothetical protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
WP_001148590.1\|2208241_2208991_+	antirepressor	A0A1W6JPN2	Staphylococcus_phage	2.0e-136	100.0
WP_000435343.1\|2209003_2209264_+	hypothetical protein	A0A2I6PDT7	Staphylococcus_phage	3.5e-40	100.0
WP_001662405.1\|2209283_2209421_+	hypothetical protein	A0ZS11	Staphylococcus_virus	3.7e-17	97.8
WP_001120936.1\|2209496_2209817_+	DUF771 domain-containing protein	A0A1W6JPI1	Staphylococcus_phage	7.4e-56	100.0
WP_000066011.1\|2209813_2209975_+	DUF1270 domain-containing protein	Q4ZAZ7	Staphylococcus_virus	2.5e-20	100.0
WP_000291488.1\|2210067_2210328_+	DUF1108 family protein	A0A2I6PDH1	Staphylococcus_phage	2.6e-43	100.0
WP_001205732.1\|2210336_2210600_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000700571.1\|2210608_2212552_+	AAA family ATPase	I1W619	Staphylococcus_phage	0.0e+00	100.0
WP_000138481.1\|2212553_2213474_+	recombinase	A0A1V0E5D7	Staphylococcus_phage	1.0e-166	100.0
WP_075583747.1\|2213602_2214172_+	MBL fold metallo-hydrolase	A0A2I6PDI9	Staphylococcus_phage	2.5e-86	99.4
WP_000610647.1\|2214172_2214643_+	single-stranded DNA-binding protein	A0A1P8L6D9	Staphylococcus_phage	9.7e-81	99.4
WP_000338528.1\|2215541_2215760_+	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
WP_000401966.1\|2215768_2216173_+	RusA family crossover junction endodeoxyribonuclease	A0A0E3XBN4	Staphylococcus_phage	4.2e-72	99.3
WP_000101270.1\|2216185_2216554_+	hypothetical protein	A0A0E3XD52	Staphylococcus_phage	6.7e-53	100.0
WP_000131377.1\|2216557_2216800_+	hypothetical protein	R9QT89	Staphylococcus_phage	3.0e-41	100.0
WP_000693615.1\|2216813_2217200_+	hypothetical protein	I1W655	Staphylococcus_phage	4.1e-69	100.0
WP_000982708.1\|2217387_2217837_+	hypothetical protein	A0A2I6PDH2	Staphylococcus_phage	9.3e-81	100.0
WP_001105621.1\|2217833_2218118_+	hypothetical protein	E9LT36	Staphylococcus_phage	2.7e-46	100.0
WP_001065084.1\|2218110_2218365_+	DUF1024 family protein	A0A2I6PDI5	Staphylococcus_phage	2.1e-37	96.4
WP_075583749.1\|2218327_2218522_+	hypothetical protein	M1SVE4	Staphylococcus_phage	6.9e-25	95.2
WP_000185642.1\|2218514_2219048_+	dUTP pyrophosphatase	A0A059T5A7	Staphylococcus_phage	2.1e-92	97.2
WP_000195809.1\|2219084_2219372_+	DUF1381 domain-containing protein	Q4ZAB6	Staphylococcus_virus	2.4e-45	98.9
WP_000608280.1\|2219364_2219601_+	hypothetical protein	A0A2I6PDD1	Staphylococcus_phage	4.8e-36	98.7
WP_031922422.1\|2219584_2219980_+	phage protein	A0A2I6PDC1	Staphylococcus_phage	6.9e-64	97.7
WP_000595265.1\|2219976_2220126_+	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000265043.1\|2220125_2220326_+	DUF1514 family protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
WP_000590122.1\|2220353_2220770_+	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_000988333.1\|2221001_2221301_+	HNH endonuclease	A0A1W6JPL7	Staphylococcus_phage	2.7e-52	100.0
WP_000402904.1\|2221430_2221775_+	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000625086.1\|2221771_2223433_+\|terminase	terminase large subunit	Q8LTH3	Staphylococcus_phage	0.0e+00	99.8
WP_000025268.1\|2223448_2224612_+\|portal	phage portal protein	A0A1W6JPQ9	Staphylococcus_phage	1.8e-216	100.0
WP_000861911.1\|2224595_2225333_+\|protease	Clp protease ClpP	A0A1W6JPK0	Staphylococcus_phage	1.8e-129	100.0
WP_000154567.1\|2225355_2226501_+\|capsid	phage major capsid protein	A0A1W6JPL4	Staphylococcus_phage	1.9e-215	100.0
WP_000238240.1\|2226520_2226805_+	hypothetical protein	A0A1W6JPL8	Staphylococcus_phage	2.3e-45	100.0
WP_000150936.1\|2226794_2227079_+\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000755150.1\|2227062_2227425_+\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_000114341.1\|2227421_2227826_+	hypothetical protein	A0A1W6JPJ1	Staphylococcus_phage	2.5e-69	100.0
WP_000565498.1\|2227822_2228230_+	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000985141.1\|2228230_2228872_+\|tail	phage tail protein	A0A1W6JPP5	Staphylococcus_phage	1.1e-119	100.0
WP_094969686.1\|2228832_2229138_+	hypothetical protein	A0A075LYE8	Staphylococcus_phage	1.5e-29	93.2
WP_001096355.1\|2229189_2229540_+	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_001549167.1\|2229590_2229728_+	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
WP_014667731.1\|2229784_2234314_+\|tail	phage tail tape measure protein	A0EX03	Staphylococcus_phage	0.0e+00	96.8
WP_000567389.1\|2234310_2235795_+\|tail	phage tail protein	A0A068A242	Staphylococcus_phage	2.0e-297	99.8
WP_000582168.1\|2235810_2239596_+	hypothetical protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.4
WP_001153681.1\|2239585_2239738_+	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_001040261.1\|2239784_2240072_+	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_000539688.1\|2240129_2240426_+	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_011447039.1\|2240575_2240752_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_001791821.1\|2240804_2240912_-	hypothetical protein	NA	NA	NA	NA
WP_000611512.1\|2240963_2241218_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_000861039.1\|2241229_2241985_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	2.2e-151	99.6
WP_000919349.1\|2242175_2242667_+	staphylokinase	A0A1X9H028	Staphylococcus_phage	1.2e-86	99.4
WP_165596011.1\|2243310_2243652_+	hypothetical protein	R9QTN8	Staphylococcus_phage	6.4e-58	97.3
WP_000727649.1\|2243746_2244196_-	chemotaxis-inhibiting protein CHIPS	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
WP_000702263.1\|2244880_2245231_+	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_001791826.1\|2245283_2245544_-	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000669789.1\|2245854_2246034_-	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_000669724.1\|2246991_2249040_+	MAP domain-containing protein	NA	NA	NA	NA
WP_001068520.1\|2249318_2250605_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000990056.1\|2250804_2250903_+	hypothetical protein	NA	NA	NA	NA
WP_000681967.1\|2251145_2251304_+	hypothetical protein	NA	NA	NA	NA
WP_000691586.1\|2251580_2251961_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000991299.1\|2251957_2252854_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	6.5e-17	30.2
WP_000645731.1\|2252854_2253535_+	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000763048.1\|2253531_2254404_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_001221654.1\|2254403_2255144_+	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000182843.1\|2255209_2255773_-	thioredoxin family protein	NA	NA	NA	NA
WP_000966288.1\|2255893_2256418_+	membrane protein	NA	NA	NA	NA
WP_001033968.1\|2256477_2257035_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000713068.1\|2257031_2257874_+	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001188075.1\|2257930_2258971_-	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000267034.1\|2259421_2259595_+	hypothetical protein	NA	NA	NA	NA
WP_000706211.1\|2260140_2261253_+\|integrase	tyrosine-type recombinase/integrase	P97010	Streptococcus_pyogenes_phage	8.7e-11	31.0
WP_000026854.1\|2261255_2263319_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
2271061:2271078	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2379514 : 2387195

Staphylococcus_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010922839.1\|2379514_2380297_+	staphylococcal enterotoxin type O	A0A1X9H080	Staphylococcus_phage	1.1e-31	36.7
WP_000821657.1\|2380577_2381297_+	staphylococcal enterotoxin type M	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
WP_000713843.1\|2381331_2382060_+	staphylococcal enterotoxin type I	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
WP_000764690.1\|2382213_2382984_+	staphylococcal enterotoxin type C1/U	A0A097PAT7	Streptococcus_pyogenes_phage	6.3e-45	43.6
WP_001236362.1\|2383022_2383778_+	staphylococcal enterotoxin type N	A0A075M4C7	Staphylococcus_phage	6.0e-40	41.4
WP_000736712.1\|2384060_2384837_+	staphylococcal enterotoxin type G	NA	NA	NA	NA
WP_094752959.1\|2386065_2387195_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	5.2e-80	54.7

DBSCAN-SWA_9

2394167 : 2410604

Staphylococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001670380.1\|2394167_2394272_+\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	7.2e-05	87.5
WP_000070809.1\|2394851_2395235_+	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|2395245_2395422_+	hypothetical protein	NA	NA	NA	NA
WP_000809864.1\|2395423_2395609_+	hypothetical protein	NA	NA	NA	NA
WP_000864144.1\|2395794_2396364_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	1.2e-77	95.0
WP_000414208.1\|2396560_2397133_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	7.8e-24	93.1
WP_000627536.1\|2397233_2397575_-	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	2.5e-54	92.9
WP_000669029.1\|2397615_2398242_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	6.4e-88	91.8
WP_000070659.1\|2398317_2399313_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.9e-70	95.2
WP_012840523.1\|2400344_2400800_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.6e-80	99.3
WP_000348357.1\|2400958_2402437_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.6e-283	97.6
WP_000778514.1\|2402441_2403443_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.8e-186	97.9
WP_000718108.1\|2403439_2403697_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	2.0e-40	90.6
WP_000672017.1\|2403762_2404236_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.6e-83	98.1
WP_075583752.1\|2404240_2404987_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.8e-141	97.6
WP_000109899.1\|2405364_2406957_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_000933826.1\|2407327_2408521_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.2e-217	99.5
WP_000366153.1\|2408645_2409554_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	2.9e-137	98.7
WP_000453297.1\|2409770_2410604_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.0e-158	99.3

DBSCAN-SWA_10

2423334 : 2432338

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163242.1\|2423334_2423730_-	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	4.5e-71	96.9
WP_000989106.1\|2423747_2425040_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	7.5e-216	94.2
WP_000221190.1\|2425039_2425354_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	1.3e-52	98.1
WP_001261675.1\|2425880_2427383_+	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000384183.1\|2427875_2428907_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
WP_000493892.1\|2428913_2429546_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_001159035.1\|2429556_2430738_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
WP_001008551.1\|2430750_2431215_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001196354.1\|2431336_2432338_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7

DBSCAN-SWA_11

2435499 : 2448238

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000764423.1\|2435499_2436063_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	2.2e-103	100.0
WP_000526539.1\|2436059_2437013_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_001025067.1\|2437123_2438305_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
WP_001108729.1\|2438595_2441010_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.3
WP_000836465.1\|2441031_2441343_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001050580.1\|2441668_2448238_+	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.9e-294	92.6

DBSCAN-SWA_12

2571195 : 2580238

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001005767.1\|2571195_2572200_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
WP_001008435.1\|2572201_2573227_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001112045.1\|2573249_2574389_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001160682.1\|2574407_2574668_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_000749795.1\|2574942_2577222_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_000595016.1\|2577424_2579698_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.1e-63	29.0
WP_000364542.1\|2579719_2580238_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_13

2649684 : 2658014

Caulobacter_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217257.1\|2649684_2651502_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.3
WP_001283055.1\|2651725_2652832_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_000624578.1\|2652962_2653640_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_000683937.1\|2653642_2654743_+	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_001062179.1\|2654856_2656203_+	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	9.1e-55	33.7
WP_000924214.1\|2656212_2657103_+	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001213908.1\|2657228_2658014_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3

DBSCAN-SWA_14

2713133 : 2796595

106

Staphylococcus_phage(80.77%)

holin,portal,tRNA,integrase,capsid,terminase,plate,tail,head,protease

attL 2717054:2717071|attR 2791672:2791689

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000064078.1\|2713133_2713859_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-45	43.0
WP_000987779.1\|2713839_2715591_+	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	1.3e-21	33.6
WP_001670353.1\|2715842_2716760_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001816962.1\|2716762_2718799_+	hypothetical protein	B5WZK7	Staphylococcus_phage	4.0e-54	53.7
2717054:2717071	attL	NA	NA	NA	NA
WP_000264751.1\|2718841_2720047_-\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
WP_000191464.1\|2720172_2720787_+	hypothetical protein	M9QRQ8	Staphylococcus_phage	2.5e-105	99.5
WP_001795334.1\|2720783_2720930_-	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.2e-16	100.0
WP_000705240.1\|2720966_2721149_-	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
WP_000511090.1\|2721219_2721951_-	helix-turn-helix transcriptional regulator	S4SVC5	Staphylococcus_phage	1.3e-132	99.2
WP_000213811.1\|2722102_2722315_+	helix-turn-helix transcriptional regulator	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
WP_000435357.1\|2722362_2722806_+	hypothetical protein	A7TWF2	Staphylococcus_phage	8.9e-76	100.0
WP_000771849.1\|2722820_2722970_+	hypothetical protein	D2JGJ0	Staphylococcus_phage	1.4e-20	100.0
WP_000362644.1\|2723010_2723223_-	hypothetical protein	D2JGJ1	Staphylococcus_phage	7.6e-33	100.0
WP_001148860.1\|2723292_2723490_+	hypothetical protein	A7TWF5	Staphylococcus_phage	4.6e-24	100.0
WP_000773059.1\|2723476_2723857_-	DUF2513 domain-containing protein	Q4ZCQ5	Staphylococcus_virus	5.8e-68	100.0
WP_001025401.1\|2723923_2724169_+	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_001128433.1\|2724137_2724503_-	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001097552.1\|2724557_2724773_+	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
WP_001124160.1\|2724797_2725061_+	helix-turn-helix domain-containing protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
WP_001285954.1\|2725073_2725235_+	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_000175000.1\|2725313_2725637_+	hypothetical protein	A0A2I6PDL5	Staphylococcus_phage	1.3e-52	100.0
WP_000985986.1\|2725651_2726014_+	hypothetical protein	Q4ZCP8	Staphylococcus_virus	2.2e-56	100.0
WP_000762534.1\|2726010_2727177_+	DUF2800 domain-containing protein	R4WAL0	Staphylococcus_phage	7.0e-221	99.7
WP_000647288.1\|2727202_2727757_+	DUF2815 family protein	M9QRS1	Staphylococcus_phage	1.4e-99	100.0
WP_075583731.1\|2727825_2729778_+	DNA polymerase	Q4ZCP5	Staphylococcus_virus	0.0e+00	99.4
WP_001164629.1\|2729790_2729976_+	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_000113975.1\|2729975_2730377_+	PVL family protein	A0A2I6PF14	Staphylococcus_phage	3.6e-68	98.5
WP_000022728.1\|2730376_2730634_+	DUF3310 domain-containing protein	A0A2I6PEN5	Staphylococcus_phage	2.6e-43	100.0
WP_000235324.1\|2730636_2730837_+	hypothetical protein	A0A2I6PEM3	Staphylococcus_phage	2.5e-30	100.0
WP_000132191.1\|2730851_2731094_+	hypothetical protein	A0A2D1G5G2	Staphylococcus_phage	2.8e-39	97.5
WP_001065075.1\|2731108_2731357_+	DUF1024 family protein	Q9B0F3	Staphylococcus_virus	2.7e-37	97.6
WP_000185638.1\|2731349_2731877_+	dUTP pyrophosphatase	A7TWB1	Staphylococcus_phage	7.8e-95	100.0
WP_000195806.1\|2731913_2732150_+	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	3.1e-35	98.7
WP_000483477.1\|2732174_2732411_+	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
WP_001798107.1\|2732394_2732787_+	hypothetical protein	A7TWI1	Staphylococcus_phage	3.1e-64	98.5
WP_024937088.1\|2732786_2732939_+	transcriptional regulator	A7TWI2	Staphylococcus_phage	1.4e-17	94.0
WP_000265258.1\|2733006_2733207_+	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_000884844.1\|2733258_2735706_+	hypothetical protein	R4WAL1	Staphylococcus_phage	0.0e+00	100.0
WP_001801650.1\|2735814_2735913_-	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	3.7e-11	100.0
WP_000665203.1\|2736046_2736337_+	VRR-NUC domain-containing protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
WP_075583730.1\|2736317_2737685_+	DEAD/DEAH box helicase	A0A2I6PE95	Staphylococcus_phage	1.9e-262	99.8
WP_000513699.1\|2737697_2738135_+	transcriptional regulator	A0A2I6PDC2	Staphylococcus_phage	4.6e-77	100.0
WP_000160689.1\|2738291_2738606_+	HNH endonuclease	A0A2I6PDC4	Staphylococcus_phage	2.5e-56	100.0
WP_000778932.1\|2738734_2739040_+\|terminase	terminase	A0A2I6PE27	Staphylococcus_phage	2.9e-49	100.0
WP_000153554.1\|2739029_2740721_+\|terminase	terminase large subunit	A0A1X9IGU0	Staphylococcus_phage	0.0e+00	99.8
WP_001100664.1\|2740725_2741964_+\|portal	phage portal protein	A0A2I6PER5	Staphylococcus_phage	6.9e-235	100.0
WP_000061866.1\|2741947_2742721_+\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
WP_001670346.1\|2742732_2743896_+\|capsid	phage major capsid protein	A0A2I6PEQ3	Staphylococcus_phage	2.1e-217	99.7
WP_000050973.1\|2743964_2744243_+\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_000395498.1\|2744254_2744587_+	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
WP_000110023.1\|2744583_2744985_+	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
WP_001023806.1\|2744985_2745381_+	DUF3168 domain-containing protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
WP_000807536.1\|2745415_2746057_+\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_000169127.1\|2746148_2746604_+	Ig domain-containing protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
WP_000589167.1\|2746661_2747012_+	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
WP_000438833.1\|2747053_2747212_+	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_001670344.1\|2747225_2753426_+\|tail	phage tail tape measure protein	A0A1X9IGU9	Staphylococcus_phage	0.0e+00	100.0
WP_001190527.1\|2753425_2754250_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	7.8e-158	99.6
WP_000384475.1\|2754258_2755842_+	peptidase	A0A2I6PEQ5	Staphylococcus_phage	3.5e-308	99.8
WP_000179858.1\|2755841_2756132_+	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
WP_000429558.1\|2756147_2758058_+	minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
WP_000067127.1\|2758057_2759524_+\|plate	BppU family phage baseplate upper protein	A0A2I6PES7	Staphylococcus_phage	1.5e-273	100.0
WP_001166596.1\|2759523_2759913_+	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	4.9e-62	99.2
WP_000916020.1\|2759905_2760070_+	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_000466784.1\|2760115_2760415_+	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_011447039.1\|2760567_2760744_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_001791821.1\|2760796_2760904_-	hypothetical protein	NA	NA	NA	NA
WP_000611512.1\|2760955_2761210_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_000861038.1\|2761221_2761977_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_001003363.1\|2762337_2764242_+	N-6 DNA methylase	A0A1W6JNK1	Staphylococcus_phage	0.0e+00	84.5
WP_000777019.1\|2764228_2765239_+	hypothetical protein	A0A1W6JNN3	Staphylococcus_phage	2.7e-64	41.3
WP_000333560.1\|2765285_2765633_+	hypothetical protein	Q4ZCJ7	Staphylococcus_virus	1.5e-25	98.2
WP_024928067.1\|2765723_2766659_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001021507.1\|2766642_2766789_+	hypothetical protein	NA	NA	NA	NA
WP_001805732.1\|2766863_2767772_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001805730.1\|2768226_2769171_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001186912.1\|2769572_2770118_+	ECF transporter S component	NA	NA	NA	NA
WP_001151997.1\|2770223_2770472_-	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001163816.1\|2770579_2771533_+	hypothetical protein	NA	NA	NA	NA
WP_000902100.1\|2771522_2772902_+	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	6.4e-56	33.3
WP_000069285.1\|2773054_2774506_+	elastin-binding protein EbpS	NA	NA	NA	NA
WP_031789483.1\|2774631_2774748_+	hypothetical protein	NA	NA	NA	NA
WP_001174259.1\|2774908_2775877_+	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_000681755.1\|2776009_2776978_-	asparaginase	NA	NA	NA	NA
WP_000644390.1\|2777054_2777714_+	(d)CMP kinase	NA	NA	NA	NA
WP_001805731.1\|2777744_2777861_+	hypothetical protein	NA	NA	NA	NA
WP_031789482.1\|2777977_2778169_+	hypothetical protein	NA	NA	NA	NA
WP_000133951.1\|2778425_2779601_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_000165530.1\|2779822_2781133_+	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000161746.1\|2781149_2782148_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_001043863.1\|2782318_2782591_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000450555.1\|2783021_2783594_+	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_000774675.1\|2783596_2784322_+	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_075583706.1\|2784338_2785283_+	heptaprenyl diphosphate synthase	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000442480.1\|2785374_2785824_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_000789525.1\|2786033_2786234_+	hypothetical protein	NA	NA	NA	NA
WP_001269918.1\|2786620_2787787_+	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-34	32.1
WP_000776316.1\|2787812_2788877_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_000245908.1\|2788886_2790185_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_001670342.1\|2790191_2791436_+	hypothetical protein	NA	NA	NA	NA
WP_000005215.1\|2791449_2792025_+	IDEAL domain-containing protein	G3MAV7	Bacillus_virus	7.9e-08	26.7
2791672:2791689	attR	NA	NA	NA	NA
WP_000154682.1\|2792014_2792602_+	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_001827022.1\|2792673_2793354_+	zinc metallopeptidase	NA	NA	NA	NA
WP_000839926.1\|2793690_2794008_+	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_000690025.1\|2794245_2795388_+	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000361546.1\|2795392_2796595_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.9e-35	43.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP026065

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP026064

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection