CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP011626	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-6538, complete sequence	0 crisprs	NA	0	0	0
NZ_CP011625	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-1919, complete sequence	0 crisprs	NA	0	0	0
NZ_CP011630	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-49, complete sequence	0 crisprs	RT	0	0	1
NZ_CP011634	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-228, complete sequence	0 crisprs	NA	0	0	8
NZ_CP011633	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-150, complete sequence	0 crisprs	csa3	0	0	1
NZ_CP011629	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-34, complete sequence	0 crisprs	NA	0	0	0
NZ_CP011632	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-84, complete sequence	0 crisprs	NA	0	0	1
NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	1 crisprs	PD-DExK	0	7	1
NZ_CP011628	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-16, complete sequence	0 crisprs	NA	0	0	0
NZ_CP011627	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-14, complete sequence	0 crisprs	NA	0	0	0
NZ_CP011631	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-54, complete sequence	0 crisprs	DEDDh	0	0	1
NZ_CP011636	Klebsiella oxytoca strain CAV1374 chromosome, complete genome	5 crisprs	cas14j,csa3,cas3,DEDDh,Cas9_archaeal,DinG,WYL	1	1	17

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

55256 : 102091

Salmonella_phage(23.53%)

transposase,integrase

attL 51037:51051|attR 95238:95252

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
51037:51051	attL	NA	NA	NA	NA
WP_047722638.1\|55256_56546_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	5.9e-120	53.0
WP_071846025.1\|56642_57017_+	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	1.4e-26	55.0
WP_032740676.1\|57886_58852_-	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	1.2e-154	88.8
WP_047722641.1\|58851_60018_-	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	1.2e-223	97.4
WP_042936824.1\|60727_61738_+	replication initiation protein	J9Q7H0	Salmonella_phage	1.1e-86	55.0
WP_001515717.1\|62562_63303_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
WP_022064516.1\|64446_65394_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	5.1e-12	30.6
WP_052958981.1\|65420_66167_-	EAL domain-containing protein	NA	NA	NA	NA
WP_023292103.1\|67669_67927_-	hypothetical protein	NA	NA	NA	NA
WP_032425611.1\|69865_70897_+\|transposase	IS630-like element ISEc33 family transposase	NA	NA	NA	NA
WP_174805835.1\|71757_72189_-	hypothetical protein	NA	NA	NA	NA
WP_000272716.1\|73116_73365_+	hypothetical protein	NA	NA	NA	NA
WP_020805590.1\|73361_73934_+	hypothetical protein	NA	NA	NA	NA
WP_020805591.1\|73964_74459_+	hypothetical protein	NA	NA	NA	NA
WP_004197807.1\|74502_74871_+	hypothetical protein	NA	NA	NA	NA
WP_004197808.1\|74904_75108_+	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_004197809.1\|75121_75325_+	hypothetical protein	NA	NA	NA	NA
WP_000427623.1\|75506_76511_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_176392666.1\|76589_76826_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.5e-21	46.2
WP_016236504.1\|77812_78370_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	2.6e-48	82.1
WP_000993245.1\|78499_78712_-	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_001087807.1\|78777_79014_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001277466.1\|79010_79376_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_000209296.1\|79393_81079_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-39	29.1
WP_000522996.1\|81117_81543_-	organomercurial transporter MerC	NA	NA	NA	NA
WP_000732275.1\|81570_81846_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001294656.1\|81861_82227_-	mercuric ion transporter MerT	NA	NA	NA	NA
WP_001166628.1\|82298_82754_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_045270086.1\|82802_83378_+	lipid IV(A) palmitoyltransferase PagP	NA	NA	NA	NA
WP_024196075.1\|83385_84309_-	acyltransferase	NA	NA	NA	NA
WP_045270087.1\|84501_87558_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	2.5e-52	22.0
WP_016241530.1\|87557_88643_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_016241528.1\|89167_89599_+	universal stress protein	A0A1W6JNV4	Morganella_phage	2.0e-24	44.1
WP_016241527.1\|89649_92337_+	cation-transporting P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	1.2e-71	27.5
WP_000509966.1\|92726_93332_-	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	5.5e-20	35.3
WP_023307208.1\|93426_96324_+\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	5.5e-182	37.8
95238:95252	attR	NA	NA	NA	NA
WP_071846027.1\|96339_97251_-	serine dehydratase subunit alpha family protein	NA	NA	NA	NA
WP_000948259.1\|97598_98240_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_000449980.1\|98239_99178_-	MCE family protein	NA	NA	NA	NA
WP_001325019.1\|99179_99971_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.8e-10	27.7
WP_001325018.1\|99976_101122_-	ABC transporter permease	NA	NA	NA	NA
WP_001067855.1\|101386_102091_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP011631

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 53353

Klebsiella_phage(83.33%)

portal,head,tail,capsid,terminase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020317538.1\|72_390_-\|head,tail	phage gp6-like head-tail connector protein	Q6UAX4	Klebsiella_phage	1.5e-45	89.8
WP_040120190.1\|370_766_-	hypothetical protein	Q6UAX5	Klebsiella_phage	1.7e-17	79.2
WP_032408953.1\|824_2111_-\|capsid	phage major capsid protein	Q6UAX6	Klebsiella_phage	2.4e-206	85.0
WP_014907815.1\|2188_3109_-	S49 family peptidase	Q6UAX7	Klebsiella_phage	9.6e-149	88.2
WP_023339403.1\|3145_4405_-\|portal	phage portal protein	Q6UAX8	Klebsiella_phage	2.5e-224	90.5
WP_047722515.1\|4577_6287_-\|terminase	terminase large subunit	Q6UAY0	Klebsiella_phage	0.0e+00	94.9
WP_032408957.1\|6321_6756_-\|terminase	P27 family phage terminase small subunit	Q6UAY1	Klebsiella_phage	2.4e-73	95.8
WP_023339406.1\|7257_7689_-	hypothetical protein	Q6UAS0	Klebsiella_phage	2.9e-39	59.9
WP_023339407.1\|7685_7970_-	hypothetical protein	Q6UAS1	Klebsiella_phage	2.4e-05	37.5
WP_032414214.1\|7966_8329_-	HNH endonuclease	Q6UAS2	Klebsiella_phage	7.8e-62	92.5
WP_023339408.1\|8312_9389_-	hypothetical protein	Q6UAS3	Klebsiella_phage	9.8e-36	37.4
WP_032408961.1\|9558_9858_-	DUF4406 domain-containing protein	Q6UAS4	Klebsiella_phage	3.0e-51	96.0
WP_162897782.1\|9866_10085_-	hypothetical protein	Q6UAS5	Klebsiella_phage	2.9e-11	97.0
WP_032408962.1\|10111_10588_-	hypothetical protein	Q6UAS7	Klebsiella_phage	2.3e-61	79.7
WP_032413535.1\|10604_11096_-	hypothetical protein	Q6UAS8	Klebsiella_phage	1.4e-82	90.2
WP_023339388.1\|11092_11404_-	hypothetical protein	Q6UAS9	Klebsiella_phage	6.3e-44	89.1
WP_032413536.1\|11462_12524_-	site-specific DNA-methyltransferase	Q6UAT0	Klebsiella_phage	1.6e-171	93.2
WP_032408967.1\|12841_13069_-	hypothetical protein	Q6UAT1	Klebsiella_phage	1.6e-28	84.0
WP_023339391.1\|13080_13302_-	hypothetical protein	O64358	Escherichia_phage	3.0e-32	90.4
WP_023339392.1\|13472_13781_+	type II toxin-antitoxin system RelE/ParE family toxin	Q6UAT3	Klebsiella_phage	3.9e-46	94.2
WP_023339393.1\|13780_14068_+	helix-turn-helix transcriptional regulator	Q6UAT4	Klebsiella_phage	1.7e-43	96.8
WP_023339395.1\|14419_14647_-	hypothetical protein	O64355	Escherichia_phage	2.8e-25	80.3
WP_032408968.1\|14667_14994_-	hypothetical protein	Q6UAT7	Klebsiella_phage	3.9e-52	94.4
WP_023339397.1\|14986_15232_-	hypothetical protein	G8C7U9	Escherichia_phage	5.1e-25	83.1
WP_052958978.1\|15228_15705_-	hypothetical protein	Q6UAU1	Klebsiella_phage	1.9e-15	60.3
WP_047722516.1\|15832_16441_-	3'-5' exonuclease	Q6UAU3	Klebsiella_phage	8.7e-98	88.0
WP_032414210.1\|16852_17590_-	phage antitermination Q family protein	Q6UAU4	Klebsiella_phage	1.2e-117	83.3
WP_032408972.1\|17579_17789_-	Cro/Cl family transcriptional regulator	Q6UAU5	Klebsiella_phage	7.7e-30	92.8
WP_032414212.1\|17869_18478_+	XRE family transcriptional regulator	Q6UAU6	Klebsiella_phage	4.8e-104	92.1
WP_047722519.1\|18728_22733_+	hypothetical protein	A0A2I6TD01	Escherichia_phage	0.0e+00	81.1
WP_047722521.1\|22725_23022_+	hypothetical protein	NA	NA	NA	NA
WP_047722522.1\|23018_23369_+	hypothetical protein	O64343	Escherichia_phage	8.6e-50	77.6
WP_155884413.1\|23411_23579_+	hypothetical protein	NA	NA	NA	NA
WP_047722525.1\|24137_24368_+	hypothetical protein	NA	NA	NA	NA
WP_047722527.1\|24364_25144_+	Bro-N domain-containing protein	O64341	Escherichia_phage	3.7e-117	79.8
WP_032408985.1\|25198_27121_-	protelomerase	Q6UAV6	Klebsiella_phage	0.0e+00	94.8
WP_023339381.1\|27828_28992_+	plasmid-partitioning protein SopA	Q6UAV7	Klebsiella_phage	2.1e-225	98.4
WP_047722529.1\|28994_29996_+	ParB/RepB/Spo0J family plasmid partition protein	Q6UAV8	Klebsiella_phage	8.0e-157	87.2
WP_016947617.1\|30096_31077_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	98.8
WP_047722530.1\|31238_32738_-\|tail	tail fiber domain-containing protein	A0A0P0IDN1	Klebsiella_phage	1.7e-147	73.8
WP_047722532.1\|32799_44712_-	DUF1983 domain-containing protein	Q6UAW1	Klebsiella_phage	0.0e+00	48.6
WP_032447254.1\|44774_45368_-\|tail	tail assembly protein	Q6UAW2	Klebsiella_phage	3.7e-85	80.7
WP_052958979.1\|45384_46212_-	hypothetical protein	A0A0P0IYG9	Acinetobacter_phage	1.3e-08	44.0
WP_039814703.1\|46258_46969_-	C40 family peptidase	Q6UAW4	Klebsiella_phage	6.7e-134	89.8
WP_020803197.1\|46970_47726_-\|tail	phage minor tail protein L	Q6UAW5	Klebsiella_phage	6.7e-124	80.1
WP_017898999.1\|47722_48061_-\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	2.4e-57	88.4
WP_047722543.1\|48060_51417_-\|tail	phage tail tape measure protein	Q6UAW7	Klebsiella_phage	0.0e+00	87.1
WP_014228914.1\|51649_52015_-\|tail	phage tail protein	Q6UAW8	Klebsiella_phage	1.6e-51	89.3
WP_014228913.1\|52072_52534_-\|tail	major tail shaft subunit	Q6UAX0	Klebsiella_phage	7.8e-67	83.7
WP_017898997.1\|52565_52967_-	HK97 gp10 family phage protein	Q6UAX1	Klebsiella_phage	1.7e-62	94.0
WP_017880258.1\|52963_53353_-	hypothetical protein	Q6UAX2	Klebsiella_phage	9.6e-58	86.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP011634

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 6939

uncultured_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000843494.1\|453_651_-	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_001514621.1\|691_3139_-	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	3.8e-83	35.4
WP_009654300.1\|3265_3706_-	hypothetical protein	NA	NA	NA	NA
WP_042946271.1\|3792_6939_-	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	S5VTK5	Leptospira_phage	1.0e-61	22.6

DBSCAN-SWA_2

10312 : 13636

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000697968.1\|10312_10993_+	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.7e-31	36.0
WP_007374412.1\|10985_12461_+	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.0e-27	30.1
WP_009309902.1\|12706_13138_+	silver-binding protein SilE	NA	NA	NA	NA
WP_004187110.1\|13285_13636_+	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	6.0e-19	51.4

DBSCAN-SWA_3

20237 : 106755

Salmonella_phage(17.24%)

integrase,transposase

attL 14132:14147|attR 80184:80200

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
14132:14147	attL	NA	NA	NA	NA
WP_040118529.1\|20237_21020_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	4.9e-53	91.2
14132:14147	attL	NA	NA	NA	NA
WP_040118530.1\|21064_21760_-	replication initiation protein	I3WF20	Macacine_betaherpesvirus	8.6e-25	31.6
WP_040118542.1\|22551_23481_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	4.2e-75	55.0
WP_040118531.1\|23581_23845_-	hypothetical protein	NA	NA	NA	NA
WP_047722685.1\|23864_24485_-	recombinase family protein	M9Q1K0	Clostridium_phage	2.1e-06	29.3
24415:24430	attR	NA	NA	NA	NA
WP_077250517.1\|24646_24805_+	hypothetical protein	A0A0U2RK18	Escherichia_phage	2.2e-05	69.7
24415:24430	attR	NA	NA	NA	NA
WP_040118446.1\|24783_26538_-	hypothetical protein	NA	NA	NA	NA
WP_071846033.1\|26725_26977_+	molecular chaperone DnaJ	NA	NA	NA	NA
WP_040118447.1\|27499_28366_+	ParA family protein	NA	NA	NA	NA
WP_040118448.1\|28365_29397_+	ParB/RepB/Spo0J family partition protein	S5WII0	Leptospira_phage	2.9e-08	26.1
WP_004902343.1\|29396_29834_+	hypothetical protein	NA	NA	NA	NA
WP_040118449.1\|29830_30154_+	hypothetical protein	NA	NA	NA	NA
WP_040118450.1\|30203_31583_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_040118451.1\|31632_32907_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	1.1e-155	63.5
WP_040118452.1\|32906_33332_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	4.9e-31	54.7
WP_040118453.1\|33539_33770_+	hypothetical protein	NA	NA	NA	NA
WP_040118454.1\|34205_34907_+	methylase	A0A2K9VH43	Faecalibacterium_phage	3.4e-21	33.8
WP_020314641.1\|34906_35128_+	hypothetical protein	NA	NA	NA	NA
WP_040118455.1\|35173_35584_+	DUF1380 family protein	NA	NA	NA	NA
WP_040118456.1\|35631_36399_+	hypothetical protein	NA	NA	NA	NA
WP_047722686.1\|36642_37341_-	hypothetical protein	NA	NA	NA	NA
WP_052958982.1\|37330_37642_-	hypothetical protein	NA	NA	NA	NA
WP_047722688.1\|37861_38833_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_040118457.1\|39412_39841_+	antirestriction protein	A9J566	Pseudomonas_phage	3.4e-08	30.5
WP_040118458.1\|39887_40394_+	antirestriction protein ArdA	G9FHQ1	Rhodococcus_virus	5.3e-08	31.9
WP_000761848.1\|40434_40626_+	hypothetical protein	NA	NA	NA	NA
WP_040118459.1\|40826_41090_+	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	3.4e-14	55.3
WP_047722689.1\|41113_41434_+	hypothetical protein	NA	NA	NA	NA
WP_020804459.1\|42287_42845_+	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	5.2e-49	75.2
WP_047722691.1\|42893_43142_+	DUF905 domain-containing protein	NA	NA	NA	NA
WP_040118463.1\|43210_45211_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	2.1e-23	26.8
WP_086556807.1\|45251_45686_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_071846034.1\|45682_46411_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_040118465.1\|46407_46731_+	hypothetical protein	NA	NA	NA	NA
WP_040118466.1\|47567_47906_+	hypothetical protein	A0A248SL90	Klebsiella_phage	1.2e-27	62.7
WP_040118467.1\|47965_48313_+	hypothetical protein	NA	NA	NA	NA
WP_040118468.1\|48401_48632_+	hypothetical protein	NA	NA	NA	NA
WP_040118469.1\|48678_49512_+	N-6 DNA methylase	A0A2K9V411	Faecalibacterium_phage	9.6e-23	35.3
WP_162933663.1\|49797_49968_-	hypothetical protein	NA	NA	NA	NA
WP_040118470.1\|50160_50703_+	antirestriction protein	NA	NA	NA	NA
WP_065806261.1\|50725_51208_-	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_047722692.1\|51652_52057_+	relaxosome protein TraM	NA	NA	NA	NA
WP_001166628.1\|52063_52519_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_001294656.1\|52590_52956_+	mercuric ion transporter MerT	NA	NA	NA	NA
WP_000732275.1\|52971_53247_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_000522996.1\|53274_53700_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_000209296.1\|53738_55424_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-39	29.1
WP_001277466.1\|55441_55807_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_001087807.1\|55803_56040_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_000993245.1\|56105_56318_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_003124096.1\|56448_57009_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	2.1e-50	88.6
WP_032622532.1\|57011_59978_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.8
WP_000427614.1\|60056_61061_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_015062794.1\|62471_63476_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_001138073.1\|63554_66527_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
WP_001162012.1\|66529_67087_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	5.8e-48	81.3
WP_000845054.1\|67392_68406_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	6.1e-72	45.5
WP_013263788.1\|68552_69011_+	aminoglycoside N-acetyltransferase AAC(6')-Il	NA	NA	NA	NA
WP_001007673.1\|69153_69981_+	oxacillin-hydrolyzing class D beta-lactamase OXA-2	NA	NA	NA	NA
WP_001206317.1\|70017_70809_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
WP_000679427.1\|70972_71320_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|71313_72153_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000376623.1\|72280_72781_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001381192.1\|72749_73742_-	TniB family NTP-binding protein	NA	NA	NA	NA
WP_000179844.1\|73744_75424_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_001300294.1\|75498_76167_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000993386.1\|76202_76439_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001277456.1\|76435_76798_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_047722550.1\|76815_78513_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	7.4e-38	27.6
WP_000522996.1\|78551_78977_-	organomercurial transporter MerC	NA	NA	NA	NA
WP_000732275.1\|79004_79280_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001294656.1\|79295_79661_-	mercuric ion transporter MerT	NA	NA	NA	NA
WP_001166628.1\|79732_80188_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_032489431.1\|80861_80939_-	RepA leader peptide Tap	NA	NA	NA	NA
WP_000078032.1\|81170_81413_-	replication regulatory protein RepA	NA	NA	NA	NA
WP_160887331.1\|81544_82045_-	DUF1669 domain-containing protein	A0A1B2LRT6	Wolbachia_phage	9.5e-18	34.5
WP_040118502.1\|82199_82508_-	hypothetical protein	NA	NA	NA	NA
WP_000027057.1\|82876_83737_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|83919_84477_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_001143760.1\|84640_87646_+\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
WP_032736843.1\|89899_90427_-	hypothetical protein	NA	NA	NA	NA
WP_032425611.1\|91202_92234_+\|transposase	IS630-like element ISEc33 family transposase	NA	NA	NA	NA
WP_047722693.1\|94435_95806_-	conjugal transfer protein TraH	NA	NA	NA	NA
WP_142988944.1\|95792_96407_-	type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB	NA	NA	NA	NA
WP_047722694.1\|96342_96579_-	type-F conjugative transfer system pilin chaperone TraQ	NA	NA	NA	NA
WP_042946285.1\|96589_97342_-	type-F conjugative transfer system pilin assembly protein TraF	NA	NA	NA	NA
WP_032736851.1\|97362_97689_-	hypothetical protein	NA	NA	NA	NA
WP_032736852.1\|97735_97921_-	hypothetical protein	NA	NA	NA	NA
WP_032736854.1\|97917_98154_-	conjugal transfer protein TrbE	NA	NA	NA	NA
WP_047722696.1\|98143_98755_-	hypothetical protein	NA	NA	NA	NA
WP_047722697.1\|98868_100812_-	type-F conjugative transfer system mating-pair stabilization protein TraN	NA	NA	NA	NA
WP_032736857.1\|100808_101435_-	type-F conjugative transfer system pilin assembly protein TrbC	NA	NA	NA	NA
WP_032736858.1\|101447_102440_-	conjugal transfer pilus assembly protein TraU	NA	NA	NA	NA
WP_042946288.1\|102450_103077_-	type-F conjugative transfer system protein TraW	NA	NA	NA	NA
WP_032736860.1\|103073_103463_-	type-F conjugative transfer system protein TrbI	NA	NA	NA	NA
WP_013815099.1\|105786_106755_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.1

DBSCAN-SWA_4

116228 : 174831

Escherichia_phage(16.67%)

tail,integrase,transposase

attL 159861:159877|attR 176502:176518

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004118961.1\|116228_116510_-	helix-turn-helix transcriptional regulator	A0A2I6TC97	Escherichia_phage	1.3e-08	38.0
WP_004118963.1\|116490_116820_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	3.1e-09	44.2
WP_004118966.1\|117223_117952_-	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_004118968.1\|117948_118380_-	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_047722701.1\|118423_120481_-	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	2.4e-22	26.2
WP_009654057.1\|120548_120782_-	DUF905 domain-containing protein	NA	NA	NA	NA
WP_009654061.1\|120830_121379_-	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	3.9e-49	73.8
WP_047722703.1\|122212_122776_-	methyltransferase	A0A2I7RQ20	Vibrio_phage	4.8e-18	36.7
WP_032700844.1\|122824_124207_-	DUF3560 domain-containing protein	NA	NA	NA	NA
WP_032700845.1\|124257_124488_-	hypothetical protein	NA	NA	NA	NA
WP_074172513.1\|125280_125526_-	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	1.3e-12	49.4
WP_032700847.1\|125711_125903_-	hypothetical protein	NA	NA	NA	NA
WP_032700848.1\|125980_126409_-	antirestriction protein	NA	NA	NA	NA
WP_032700849.1\|126578_127364_-	hypothetical protein	NA	NA	NA	NA
WP_032700850.1\|127417_127837_-	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_032700851.1\|127848_128070_-	hypothetical protein	NA	NA	NA	NA
WP_032700852.1\|128069_128750_-	DNA methylase	A0A2I7RE86	Vibrio_phage	2.4e-27	35.5
WP_032700853.1\|129724_129955_-	hypothetical protein	NA	NA	NA	NA
WP_032700854.1\|130018_130690_-	plasmid partitioning/stability family protein	NA	NA	NA	NA
WP_032425559.1\|130692_131664_-	StbA family protein	A0A222YXF2	Escherichia_phage	1.4e-73	46.8
WP_001568036.1\|131895_132327_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.1e-29	53.3
WP_032700856.1\|132326_133598_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	4.4e-152	63.7
WP_021312406.1\|133679_134654_-	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	6.5e-87	53.8
WP_011977818.1\|134653_135859_-	AAA family ATPase	A0A077SL49	Escherichia_phage	5.3e-163	69.3
WP_001568031.1\|136582_137338_-	replication initiation protein RepE	I3WF20	Macacine_betaherpesvirus	2.0e-136	96.0
WP_162180131.1\|138077_138191_+	hypothetical protein	NA	NA	NA	NA
WP_032700766.1\|138319_138577_+	hypothetical protein	NA	NA	NA	NA
WP_047722707.1\|138633_139422_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	4.2e-52	92.0
WP_032700767.1\|139418_139748_-	hypothetical protein	NA	NA	NA	NA
WP_032700768.1\|139976_140585_-	hypothetical protein	NA	NA	NA	NA
WP_032700769.1\|140647_141001_-	hypothetical protein	NA	NA	NA	NA
WP_004118819.1\|141694_143227_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.1e-51	39.8
WP_047722708.1\|143393_143660_-	colicin-D	NA	NA	NA	NA
WP_077258057.1\|143656_145807_-	S-type pyocin domain-containing protein	NA	NA	NA	NA
WP_047722709.1\|145887_147021_-\|tail	tail fiber domain-containing protein	A0A1Z1LZI1	Serratia_phage	1.8e-19	27.0
WP_001166628.1\|148381_148837_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_001294656.1\|148908_149274_+	mercuric ion transporter MerT	NA	NA	NA	NA
WP_000732275.1\|149289_149565_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_000522996.1\|149592_150018_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_000209296.1\|150056_151742_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-39	29.1
WP_001277466.1\|151759_152125_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_001087807.1\|152121_152358_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_000993245.1\|152423_152636_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_003124096.1\|152766_153327_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	2.1e-50	88.6
WP_032622532.1\|153329_156296_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.8
WP_000427614.1\|156374_157379_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_015062794.1\|158789_159794_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
159861:159877	attL	NA	NA	NA	NA
WP_001138073.1\|159872_162845_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
WP_001162012.1\|162847_163405_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	5.8e-48	81.3
WP_000845054.1\|163710_164724_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	6.1e-72	45.5
WP_013263788.1\|164870_165329_+	aminoglycoside N-acetyltransferase AAC(6')-Il	NA	NA	NA	NA
WP_001007673.1\|165471_166299_+	oxacillin-hydrolyzing class D beta-lactamase OXA-2	NA	NA	NA	NA
WP_001206317.1\|166335_167127_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
WP_000679427.1\|167290_167638_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|167631_168471_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000376623.1\|168598_169099_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001381192.1\|169067_170060_-	TniB family NTP-binding protein	NA	NA	NA	NA
WP_000179844.1\|170062_171742_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_001300294.1\|171816_172485_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000993386.1\|172520_172757_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001277456.1\|172753_173116_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_047722550.1\|173133_174831_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	7.4e-38	27.6
176502:176518	attR	NA	NA	NA	NA

DBSCAN-SWA_5

177862 : 194617

Enterobacteria_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160887331.1\|177862_178363_-	DUF1669 domain-containing protein	A0A1B2LRT6	Wolbachia_phage	9.5e-18	34.5
WP_040118502.1\|178517_178826_-	hypothetical protein	NA	NA	NA	NA
WP_000027057.1\|179194_180055_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|180237_180795_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_001143760.1\|180958_183964_+\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
WP_047722710.1\|184166_184487_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047722711.1\|184476_185742_+	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_023307208.1\|186257_189155_-\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	5.5e-182	37.8
WP_000509966.1\|189249_189855_+	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	5.5e-20	35.3
WP_013815099.1\|191257_192226_+\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.1
WP_142988970.1\|193415_193652_-	glycogen synthesis protein GlgS	NA	NA	NA	NA
WP_004099053.1\|193648_194617_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	5.1e-185	98.8

DBSCAN-SWA_6

200136 : 204341

Dickeya_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004197672.1\|200136_202584_+	glycogen phosphorylase	A0A140XAG6	Dickeya_phage	9.4e-26	70.5
WP_004197675.1\|202697_204341_+	alpha-D-glucose phosphate-specific phosphoglucomutase	A0A1X9I671	Streptococcus_phage	1.5e-22	25.0

DBSCAN-SWA_7

208441 : 212171

Enterobacteria_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047722713.1\|208441_208999_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	1.3e-39	45.9
WP_047722714.1\|209159_212171_+\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	63.3

DBSCAN-SWA_8

220190 : 222268

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002436614.1\|220190_221591_-	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	2.4e-18	26.6
WP_001188930.1\|221587_222268_-	copper response regulator transcription factor PcoR	W8CYM9	Bacillus_phage	8.7e-30	34.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP011632

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

34744 : 68955

Enterobacteria_phage(25.0%)

protease,integrase,transposase

attL 35865:35880|attR 69681:69696

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001143760.1\|34744_37750_-\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
35865:35880	attL	NA	NA	NA	NA
WP_001235713.1\|37913_38471_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_000027057.1\|38653_39514_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_000845048.1\|40824_41838_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_000381802.1\|41986_42520_+	aminoglycoside nucleotidyltransferase ANT(2'')-Ia	NA	NA	NA	NA
WP_004206941.1\|42599_43388_+	APH(3') family aminoglycoside O-phosphotransferase AphA16	E4ZFP6	Streptococcus_phage	1.4e-60	47.2
WP_032420064.1\|43511_44357_+	AadA family aminoglycoside 3''-O-nucleotidyltransferase	NA	NA	NA	NA
WP_001007673.1\|44386_45214_+	oxacillin-hydrolyzing class D beta-lactamase OXA-2	NA	NA	NA	NA
WP_000679427.1\|45349_45697_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|45690_46530_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000376623.1\|46657_47158_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001381192.1\|47126_48119_-	TniB family NTP-binding protein	NA	NA	NA	NA
WP_000179844.1\|48121_49801_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_001300294.1\|49875_50544_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000993386.1\|50579_50816_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001277456.1\|50812_51175_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_047722550.1\|51192_52890_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	7.4e-38	27.6
WP_000522996.1\|52928_53354_-	organomercurial transporter MerC	NA	NA	NA	NA
WP_000732275.1\|53381_53657_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001294656.1\|53672_54038_-	mercuric ion transporter MerT	NA	NA	NA	NA
WP_001166628.1\|54109_54565_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_000654805.1\|55951_56920_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	7.7e-181	96.9
WP_032491180.1\|57040_57901_+	class A extended-spectrum beta-lactamase SHV-30	A0A077SL40	Escherichia_phage	1.7e-155	99.3
WP_002210513.1\|57921_58683_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_004206881.1\|58790_61688_-\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	2.5e-182	37.8
WP_000509966.1\|61782_62388_+	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	5.5e-20	35.3
WP_004206885.1\|62970_65058_-	conjugal transfer protein TrbC	NA	NA	NA	NA
WP_004206886.1\|65070_66021_-	DsbC family protein	NA	NA	NA	NA
WP_004206887.1\|66031_67294_-	hypothetical protein	NA	NA	NA	NA
WP_004187436.1\|67338_67734_-	lytic transglycosylase domain-containing protein	NA	NA	NA	NA
WP_004206889.1\|67838_68222_-	DUF1496 domain-containing protein	NA	NA	NA	NA
WP_004206890.1\|68301_68955_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
69681:69696	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP011630

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

26766 : 37735

Escherichia_phage(37.5%)

integrase

attL 31559:31573|attR 40801:40815

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023332912.1\|26766_27468_-	DNA methylase	A0A2I7RE86	Vibrio_phage	9.3e-27	36.7
WP_001568040.1\|27904_28135_-	hypothetical protein	NA	NA	NA	NA
WP_015345000.1\|28197_28869_-	plasmid partitioning/stability family protein	NA	NA	NA	NA
WP_001568038.1\|28871_29843_-	hypothetical protein	A0A222YXF2	Escherichia_phage	1.1e-73	46.8
WP_161952885.1\|30091_31579_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.1e-29	34.1
31559:31573	attL	NA	NA	NA	NA
WP_001568036.1\|31985_32417_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.1e-29	53.3
WP_047722488.1\|32416_33688_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	3.4e-152	63.7
WP_004197644.1\|34099_34975_+	RepB family plasmid replication initiator protein	Q71TL8	Escherichia_phage	1.1e-82	56.8
WP_004197649.1\|35607_36234_+	ParA family plasmid-partitioning AAA ATPase	A0A222YXS3	Escherichia_phage	2.9e-40	43.6
WP_006788217.1\|36353_36533_+	hypothetical protein	NA	NA	NA	NA
WP_004197635.1\|36940_37735_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.5e-52	88.7
40801:40815	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_CP011636

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011636_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011636_1

509708-509798

Orphan

Consensus_repeat	Method
TCCGGGCTACCCGAACGCAGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011636_1

>merge|NZ_CP011636|1|509708-509798|CRISPRCasFinder
TCCGGGCTACCCGAACGCAGGCGGCTGTGAAGCGGATTGAATCCCCCGGATGGCGGCTGTCGCCTTATCCGGGCTACCCGATCGCAGGCGG

>NZ_CP011636|1|1|509708-509798|CRISPRCasFinder
TCCGGGCTACCCGAACGCAGGCGG	CTGTGAAGCGGATTGAATCCCCCGGATGGCGGCTGTCGCCTTA
TCCGGGCTACCCGATCGCAGGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011636.1\|WP_014839827.1\|503194_504559_-\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NZ_CP011636.1\|WP_014227293.1\|507669_508794_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|184990
NZ_CP011636.1\|WP_014839817.1\|515427_516288_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP011636.1\|WP_025107593.1\|513116_513737_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|226105
NZ_CP011636.1\|WP_047722801.1\|509246_509663_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP011636.1\|WP_047722803.1\|512099_513014_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176160
NZ_CP011636.1\|WP_032751833.1\|499456_500890_-\|PTS-N-acetylmuramic-acid-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|181971
NZ_CP011636.1\|WP_014227298.1\|499114_499351_-\|type-II-toxin-antitoxin-system-CcdA-family-antitoxin	unknown	unknown	gnl\|CDD\|377822
NZ_CP011636.1\|WP_014227296.1\|501977_503144_-\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_CP011636.1\|WP_046877096.1\|513867_514338_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|377770
NZ_CP011636.1\|WP_047722802.1\|510606_512103_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP011636.1\|WP_025107591.1\|509878_510526_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP011636.1\|WP_014227282.1\|517797_518751_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|181818
NZ_CP011636.1\|WP_047722805.1\|517003_517783_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|225130
NZ_CP011636.1\|WP_047722800.1\|504562_507670_-\|multidrug-efflux-RND-transporter-permease-subunit-EefB	unknown	unknown	gnl\|CDD\|273335
NZ_CP011636.1\|WP_025107595.1\|514593_515403_+\|lipoprotein-NlpA	unknown	unknown	gnl\|CDD\|182119
NZ_CP011636.1\|WP_009654083.1\|497750_498653_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP011636.1\|WP_009654080.1\|500914_501817_-\|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl\|CDD\|235467
NZ_CP011636.1\|WP_047722804.1\|516279_516834_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239516
NZ_CP011636.1\|WP_032751830.1\|498803_499112_-\|CcdB-family-protein	unknown	unknown	gnl\|CDD\|376629

Protein	Function_ID	Function_description	E-value
NZ_CP011636.1\|WP_014839827.1\|503194_504559_-\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	6.39623e-100
NZ_CP011636.1\|WP_014227293.1\|507669_508794_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|184990	PRK15030, PRK15030, multidrug efflux RND transporter periplasmic adaptor subunit AcrA.	3.38386e-112
NZ_CP011636.1\|WP_014839817.1\|515427_516288_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.86137e-13
NZ_CP011636.1\|WP_025107593.1\|513116_513737_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|226105	COG3576, COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase [General function prediction only].	4.23803e-13
NZ_CP011636.1\|WP_047722801.1\|509246_509663_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.15021e-10
NZ_CP011636.1\|WP_047722803.1\|512099_513014_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176160	cd08471, PBP2_CrgA_like_2, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 2. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.84129e-90
NZ_CP011636.1\|WP_032751833.1\|499456_500890_-\|PTS-N-acetylmuramic-acid-transporter-subunit-IIBC	gnl\|CDD\|181971	PRK09586, murP, PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed.	0
NZ_CP011636.1\|WP_014227298.1\|499114_499351_-\|type-II-toxin-antitoxin-system-CcdA-family-antitoxin	gnl\|CDD\|377822	pfam07362, CcdA, Post-segregation antitoxin CcdA. This family consists of several Enterobacterial post-segregation antitoxin CcdA proteins. The F plasmid-carried bacterial toxin, the CcdB protein, is known to act on DNA gyrase in two different ways. CcdB poisons the gyrase-DNA complex, blocking the passage of polymerases and leading to double-strand breakage of the DNA. Alternatively, in cells that overexpress CcdB, the A subunit of DNA gyrase (GyrA) has been found as an inactive complex with CcdB. Both poisoning and inactivation can be prevented and reversed in the presence of the F plasmid-encoded antidote, the CcdA protein.	8.08152e-21
NZ_CP011636.1\|WP_014227296.1\|501977_503144_-\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.76372e-84
NZ_CP011636.1\|WP_046877096.1\|513867_514338_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|377770	pfam07080, DUF1348, Protein of unknown function (DUF1348). This family consists of several highly conserved hypothetical proteins of around 150 residues in length. The function of this family is unknown.	4.96588e-96
NZ_CP011636.1\|WP_047722802.1\|510606_512103_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.51925e-70
NZ_CP011636.1\|WP_025107591.1\|509878_510526_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.05871e-14
NZ_CP011636.1\|WP_014227282.1\|517797_518751_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	2.3633e-104
NZ_CP011636.1\|WP_047722805.1\|517003_517783_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	1.17181e-18
NZ_CP011636.1\|WP_047722800.1\|504562_507670_-\|multidrug-efflux-RND-transporter-permease-subunit-EefB	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NZ_CP011636.1\|WP_025107595.1\|514593_515403_+\|lipoprotein-NlpA	gnl\|CDD\|182119	PRK09861, PRK09861, lipoprotein NlpA.	0
NZ_CP011636.1\|WP_009654083.1\|497750_498653_-\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.4116e-51
NZ_CP011636.1\|WP_009654080.1\|500914_501817_-\|N-acetylmuramic-acid-6-phosphate-etherase	gnl\|CDD\|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	1.42234e-175
NZ_CP011636.1\|WP_047722804.1\|516279_516834_-\|NUDIX-hydrolase	gnl\|CDD\|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	7.96195e-36
NZ_CP011636.1\|WP_032751830.1\|498803_499112_-\|CcdB-family-protein	gnl\|CDD\|376629	pfam01845, CcdB, CcdB protein.	6.2123e-41

>NZ_CP011636.1|WP_047722801.1|509246_509663_+|GNAT-family-N-acetyltransferase
MTLIITENINPADQEELLAGLREYNLRFLDPAQFGELGVYSRDDAGAMRGGLIGKRKGSWLCIDYLWVSEASRGSGLGSELMHEAENQARARGCSHVLVDTFSFQALPFYQKLGYQLQMSLPDFPHAGMQRHYLSKVL
>NZ_CP011636.1|WP_014227293.1|507669_508794_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MKYTLAPIAAALFLLSGCDNAQNASPQQMTQEVGVVTLHGQPVPVVSSLTGRTTASLSAEVRPQVGGIVQKRLFTEGDMVKAGQALYQIDPSSYRATFNEAAASLKQAQALVIADCQKAQRYAVLVKDNGVSRQDADDAIATCNQDKASVESKKAALESARINLNWTTVTAPIAGRIGISSVTPGALVSADQDTALATIRGLDTMYVDLTRSSVDLLRLRKQSLASNSDTLNVTLTLEDGSTYSEKGRLALTEVAVDESTGSVTLRAVFPNPQHVLLPGMFVRARIDEGIMNDAILAPQQGITRDAKGDATALVVDANNKVEQRSVETGETYGDKWLIVNGLKSGDRLIVEGTGKVAPGQQVKAAEVKNDGGNA
>NZ_CP011636.1|WP_047722800.1|504562_507670_-|multidrug-efflux-RND-transporter-permease-subunit-EefB
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPAIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFTSTSSSDGSVSITVTFEQGTDPDTAQVQVQNKVQQAESRLPSEVQQSGVTVEKSQSSFLLILAVYDKNNKATSSDISDWLVSNMQDPMARIEGVGSLQVFGAEYAMRIWMDPTKLASYSLMPSDVQSAIEAQNVQVSAGKIGALPASNAQQLTATVRAQSRLQTVAQFKEIIVKSKSDGSVVRLSDVARVEMGSEDYTASANLNGHPAAGIAVMMAPGANALNTATLVKNKIAEFQRQMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIILVVCVMYLFLQNFRATLIPAVAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALIAIALVLSAVFLPMAFFGGSTGVIYRQFSVTIISAMMLSVVVALTLTPALCGALLSHSKPHTKGFFGAFNRLWGRTEQGYQHRVVGGLRRSAMMMGAFVLICGGMALAMWKLPGSFLPTEDQGEIMVQYTLPAGATAVRTAEVRRQVTDWFLTKEKANTDVIFTVDGFSFSGSGQNAGMAFVSLKNWSERKGEENTAQAIALRATKELGSIRDATLFAMTPPSVDGLGQSNGFTFELMASGGTDRDSLMKMRSQLLAAANQSTELQSVRANDLPQMPQLQVDIDNNKAVSLGLSLSDVTDTLSSAWVGTYVNDFIDRGRVKKVYIQGESDARAVPSDLGKWFVRGSDDSMTPFSAFATTRWQYGPESLVRYNGSAAFEIQGENASGFSSGAAMDKMEALANNLPAGTTWAWSGMSLQEKLASGQAMSLYAISILVVFLCLAALYESWSVPFSVIMVIPLGLLGAALAAWMRGLSNDVYFQVALLTTIGLSSKNAILIVEFAESAVEEGYSLSRAAMRAAQTRLRPIVMTSLAFIAGVLPLAIATGAGANSRVAIGTGIIGGTLTATLLAVFFVPLFFVLVKRFFTRHRSSQE
>NZ_CP011636.1|WP_014839827.1|503194_504559_-|efflux-transporter-outer-membrane-subunit
MFRFTLVFVALLTAGCVSLDPHYERPAAPVPATLPGSHGEATAVVSDWQQVVNDARLKKVVNIALTSNRDVQKALADIEAARAQFGETRASLFPTLDAELSHTRSKTVASGLTSSAEADGAVSSFELDLFGKNQSLTRAARETWLASEFTAQNTRLTMIADLTTAWITLAADNSNLALAQDTMASAENSRRIVTRQMEVGTASAGDLSDAESVYQQARASVASYRTLVAQDKNALNLLAGETVPDSLLPGTLESLGDRSITLVPAGVSSSVLLRRPDIQEAEHNLKSANADIGAARANFFPSISLTASAGVGSDSLSSLFSHGMQVWSFAPSISLPLFTGGSNLAQLRYAEAEKKGLIATYEKTIQSAFKDVADALARRETLSEQLDAQNKYVAAEQKSLNIAMKSYQAGVGDYLSVLTAQRTLWSAQATLISLQQTDLENRITLWQSLGGGAS
>NZ_CP011636.1|WP_014227296.1|501977_503144_-|multidrug-effflux-MFS-transporter
MSRISLSWVVVLGLLSAIGPLCTDFYLPALPEITQQLSATGTQTQLSLTAALIGLGLGQLFFGPLSDRIGRKKPLALSLLLFIFSSAMCAITYDIHMLIAWRFLQGFAGAGGSVLSRSIARDRYQGTLLTQFFALLMTVNGIAPVLSPVLGGWIITAFDWRILFWAMAAIGVVLLLLSLTVLHETLPAKSAASATRQQADAPVLKNRRFMRYCLIQAFMMAGLFSYIGSSSFVIQSEYAMSAMQFSLLFGLNGIGLIIAALIFSRLARRFSAEALLRGGQLLAVAFAAITLLFAWLPQPTLALVGLFFTVSMMSGISTVAGSEAMNAIHARQSGTASALMGTLMFVFGGIAAPLAGLGGETMLKMSFAMTLCYLAALLIGLKKPRPIA
>NZ_CP011636.1|WP_009654080.1|500914_501817_-|N-acetylmuramic-acid-6-phosphate-etherase
MSIDLSKLLTERRNANSANIDILTTEEMLTVINQEDQQVAHAITPYLPQIAQVVDKVAAALQAGGRLIYIGAGTSGRLGILDASECPPTFGTRPEQVVGIIAGGHKAILSAVENVEDNKAQGAMDLQNLNFSSRDVLVGLAASGRTPYVIGAMEYAHSQNAFVAIVSCNPHGEMAQLADVAITPVVGPEVVTGSTRLKAGTAQKLVLNMISTGAMIRIGKVYSNLMVDVEATNAKLIERQVSIVMEATECDRATAQSALEACDRHCKTAIVMVLADLSAADAQALLAKNNGYIRKALSHS
>NZ_CP011636.1|WP_032751833.1|499456_500890_-|PTS-N-acetylmuramic-acid-transporter-subunit-IIBC
MAKINKEMIARILQHVGGAGNVAQAGNCMTRLRLTLRDESRADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQSAAEMMNALLEEAPADAPSLADVAAEKKQALKSKQTSGIQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQIFVLENAHPNATLMALIGYMKVFSKGMFTFLSILIGYNAQKAFGGSGVNGAIIAALFVLGYNPEATSGFYSGISTFFGHGIDPRGNIIGVLIAAIIGAWVERQVRRIMPANLDMILTSAVTLLIMGAITFTVIMPIGGWLFTGMSWLFLHLNGNPFGSAVLAGLFLLAVMFGVHQGFVPVYFALVDAQGFNSLFPILAMAGAGQVGAALALFWRAKHGSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKPFITACLGGACGGFFLGLVAWLGLPVGLNTVFGPSGLVALPLMTSGSGIYAGMAVYAAGLAVSYLCGFALTWLFGSKNVDLS
>NZ_CP011636.1|WP_014227298.1|499114_499351_-|type-II-toxin-antitoxin-system-CcdA-family-antitoxin
MPAAKRNKQNVSVTLDPGLVKQAREVGINLSLTLTNALKSEIHSLEIARWQKENAQAIDYLNNLTEENGLLSDEYRTF
>NZ_CP011636.1|WP_032751830.1|498803_499112_-|CcdB-family-protein
MQYYVYKNTGRIAAYPYLLDVQSDIIGKRNTRVVIPLFPLKNYKGPRADRLTPLVTVEGEEYVVMTHELASIPHRVLGEEVCNLNHQLEVVKASMDFLFDGI
>NZ_CP011636.1|WP_009654083.1|497750_498653_-|DMT-family-transporter
MGSSKKGMLNVLIAAVLWGSSGVCAQYIMQQSQMSSPFLTMTRLLFAGLILLMLSFFHGDKIFRVLQNRKDAVSLLIFSLFGALTVQYTFLMTIEQSNAATATVLQFLSPTIIVAWFAIARKTRPSPLVLAAIATSLAGTFLLVTHGNPTTLSISPTALFWGIASAFAAAFYTTYPSTLIARYGTLPIVGWSMLLGGAMLLPFYAGQGNHFVVTGGLLLAFFYLVVIGTSLTFSLYLNGAQKIGGAKAGILSCAEPLSSALLSLLLLGITFTLPDWLGTLLILSSVVLIAMDSRRRVKTA
>NZ_CP011636.1|WP_025107591.1|509878_510526_-|TetR/AcrR-family-transcriptional-regulator
MSAQKDNEAPRRPGRPRGQKSGSANREQLMDIALALFARHGIARISLNAIAKEAGVTPAMLHYYFSSREALVEKLVEERFMPLRSEIGQIFVAHGDDPVTAFTLLIETLAAMAEKNAWFAPLWMQEIIGEMPVLRQHMHARFGDEKYHKMLETVRRWQREGKLNPALSPELLFTTLISLVLVPFSRTHTDPRLQSVDRKMIVSHALALIGRGIGG
>NZ_CP011636.1|WP_047722802.1|510606_512103_+|MFS-transporter
MTSEIASQPAVPSIRLLFSALLLVMLLSALDQTIVSTALPTIVGELGGLDKLSWVVTAYILSSTIAVPLYGKFGDLFGRKIVLQVAIVLFLAGSALCGLAQNMTQLVLMRGLQGLGGGGLMVISMAAVADVIPPANRGRYQGLFGGVFGLATVIGPLIGGFLVQHASWRWIFYINLPLGLFALLVIGAVFHSSNKRSQHQIDWLGAIYLSMALLCIILFTSEGGSVRAWSDPQLWCILAFGLVGIVGFIHEERLASEPIIPLSLFRNRSFLLCSLIGFVIGMALFGSVTFLPLYLQVVKEATPTEAGLQLIPLMGGLLLTSIVSGRIISRTGKYRVFPIIGTLLGVVGMVLLTRITIHSAMWQLYLFTGVLGAGLGLVMQVLVLAVQNAMPAQMYGVATSGVTLFRSIGGSIGVALFGAVFTHVLQSNLQRLLPEGAQLPRALNPAAVQNLPAEIRLDYLDAFGSAIHAAFLMAACIMAVAFALSWLLKEAPLKTGIR
>NZ_CP011636.1|WP_047722803.1|512099_513014_-|LysR-family-transcriptional-regulator
MDRLSAMALLVKVAELGSMSAAARALNMPLTTVSRQIGELENTLGVRLMIRTTRKLTLTDAGVDYVAAARRILEEVENAERRAAGEYQEPKGELVLSAPTMFGRQHVLPVVTDFLARYPQIRVRLLLSDRNADLVGDHIDLAVRIGTLPDSGMVATRLGEMRIVTCAHPALLEKHGIPERPRELAALPIIRIESPMPYRGWRFNAEEAEDRLVALQPVLSLTTPESAADAARLGAGVARLLHYQAIDGLARGELKLLLQAMEPEPAPVHLLYTSRDLAPLKLRKFIDFAAPALRRALRRIAAAV
>NZ_CP011636.1|WP_025107593.1|513116_513737_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MPAEFLDIAMTPDVMDVQHEMGSDELWQSPHRQRRGERFGASEEAMIATRDSFYLATLSQTGWPYIQHRGGPVGFLHLLDETTLAMADFSGNRQYITTGNLRGSDRACLFLMDYPRRARLKIYATVEVVAVDADPQLLAQVAPENYRARIERIYRFHLQAFDWNCPQHITPRYTARQVAEYSQTLQQRIDELERENQRLQQLIYPK
>NZ_CP011636.1|WP_046877096.1|513867_514338_+|nuclear-transport-factor-2-family-protein
MTEQRPPLPPFTRESAAQKVRAAEDGWNSRDAAKVALAYTVESEWRNRSEFVHGRTQIIDFLQRKWRKEQEYRLIKELWAWSGNRIAVRFAYEWHDDSGNWFRSYGNENWEFDEHGLMQTRYACINDLPITESERLFHWPQGRRPDDHPGLSELGL
>NZ_CP011636.1|WP_025107595.1|514593_515403_+|lipoprotein-NlpA
MKLRLRTAAAVVLAGLLLAGCDQKGSDAKHIKVGVINGAEQDVAEVAKKVAKEKYGLDVELVGFSGSLLPNESTNAGDLDANVFQHRPFLEQDNKAHNYRLVAVGNTFVFPMAGYSRKIKSVAELKDGATIAIPNDPTNLGRALLLLQQEKLITLKAGTGLLPTAVDIIDNPHHLKIMELEGAQLPRVIDDPKVDVAIISTTYLQQTGLSPVRDGIFIEDKNSPYVNIIVTREDNKDAENVKAFIQSYQSPEVAKAAETIFNGGAVPGW
>NZ_CP011636.1|WP_014839817.1|515427_516288_+|EamA-family-transporter
MTRQRQADLLLIAATVIAACGWIFSREAIAGMPVFAFLGLRFFFAALLLLPFCRGLRVERQQWPRMIISGLWFALNLCLWIYSVSTTPSLGEGAFIMSLSMLFVPLTAWVMMKARPARAYWECLPIAVVGLGLLSLHMPIAFHPSQGWFLLTALVQSIWFCYTSKSAREVPLIPLTTVQLGITGIVGLGISAAVESWTQPFTLPTFGWLLASIVIATSLRFGLQMKGQKYAAVASAAIIMVLEPLLTVIAAALWYGEQLPLQKIIGGLLILVAQLWFRWRMLKPLR
>NZ_CP011636.1|WP_047722804.1|516279_516834_-|NUDIX-hydrolase
MKKKLTSADMHDVEVLADTPWFSMRKVGIDMAPGDRRDFFSIHYPRPAVGIVAMQDDKVLLIRHYRYLIDRVVWAIPSGGVDEGEDPREAALRELREETGWQAQRADEIIRYNPSYGSSDQLFITWLAHDLTWVGMDEDQDEVMETGWFTLEEIGQLIVRGEMPDGLSLVPLLHLMAQRRTGLA
>NZ_CP011636.1|WP_047722805.1|517003_517783_+|MBL-fold-metallo-hydrolase
MKITHVRNATQLIEYAGKKFLIDPMLSAKGAWAGFAGTARSELRNPLVELPFSIETIVDVDAVIVTHTHQDHWDEAAIAAIPKTLPVYVQHDADGQLLRGQGFCDIRLLSEDSAFADVALVKTTSGQHGSDRTYAVPAMAERLGEACGVVLRHPQEKTLWLVGDTIWRDEVEADMLRLRPDVVVLNAGYAHVIGFGPIIMGKEDVLKAHFVLPEAKIVASHMDAVNHCLLSRDELRQYVADNQIAEAVSIPQDGESMVF
>NZ_CP011636.1|WP_014227282.1|517797_518751_+|helix-turn-helix-domain-containing-protein
MKLTEVAIVAVDGFSPFHYSVPCMLFGDTVSETKRFNLHICAERPGLLSARDGFALNASGDFSLLAQADIVVVPYWGAVNQRPSQPLLDGLVRARNNGAQIVGLCLGAFVLGYAGLLDDRRAATHWEFEQDFQRQFPQVRLDINALYVDDEGIITSAGTAAALDCCLYLIRQRFGSLVANQIARRMIVPPHREGGQAQFIAQPVPKNTRDARINGLLEYLQQHIREPHNLDSLAQVAAMSRRTLTRHFAKATGMGIADWLAAERLRRSQILLEAGDLPVGQVAEEVGYRSAVTWRQQFKARFGVSPAEWRRTFRRGA

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP011636_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011636_2

1819773-1819877

Orphan

Consensus_repeat	Method
TGTCCCACCCTGTACCACTTTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011636_2

>merge|NZ_CP011636|2|1819773-1819877|CRISPRCasFinder
TGTCCCACCCTGTACCACTTTTTTAAACCAAATTCTCTAAGGTGGGACGCTGAAACCCGCGCCAGCTCTGCGTGTACCACTTGTCCCACCCTGTACCACCTTTTT

>NZ_CP011636|2|2|1819773-1819877|CRISPRCasFinder
TGTCCCACCCTGTACCACTTTTTT	AAACCAAATTCTCTAAGGTGGGACGCTGAAACCCGCGCCAGCTCTGCGTGTACCACT
TGTCCCACCCTGTACCACCTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011636.1\|WP_047723065.1\|1815437_1816460_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP011636.1\|WP_047723063.1\|1813366_1814167_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047723070.1\|1819898_1821968_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
NZ_CP011636.1\|WP_071846078.1\|1829192_1829816_+\|DUF4433-domain-containing-protein	unknown	unknown	gnl\|CDD\|373093
NZ_CP011636.1\|WP_047723071.1\|1822003_1822219_-\|AlpA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225848
NZ_CP011636.1\|WP_052959012.1\|1811963_1812527_+\|6-phospho-3-hexuloisomerase	unknown	unknown	gnl\|CDD\|132171
NZ_CP011636.1\|WP_047723062.1\|1812550_1813186_+\|3-hexulose-6-phosphate-synthase	unknown	unknown	gnl\|CDD\|132172
NZ_CP011636.1\|WP_148675610.1\|1819172_1819445_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047723067.1\|1817447_1817822_-\|PTS-glucitol/sorbitol-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226254
NZ_CP011636.1\|WP_047723074.1\|1826972_1827617_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047723064.1\|1814445_1815078_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047723072.1\|1825562_1825757_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_013815099.1\|1822646_1823615_-\|IS5-like-element-IS903B-family-transposase	unknown	unknown	gnl\|CDD\|290455
NZ_CP011636.1\|WP_047723075.1\|1827618_1828866_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|170049
NZ_CP011636.1\|WP_047723066.1\|1816470_1817451_-\|PTS-glucitol/sorbitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226255
NZ_CP011636.1\|WP_047723073.1\|1825917_1826796_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236757
NZ_CP011636.1\|WP_047723069.1\|1818711_1819122_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP011636.1\|WP_047723077.1\|1829819_1830509_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047723068.1\|1817818_1818340_-\|PTS-glucitol/sorbitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226253
NZ_CP011636.1\|WP_077258100.1\|1824551_1825325_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368573

Protein	Function_ID	Function_description	E-value
NZ_CP011636.1\|WP_047723065.1\|1815437_1816460_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.38555e-66
NZ_CP011636.1\|WP_047723070.1\|1819898_1821968_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	0
NZ_CP011636.1\|WP_047723071.1\|1822003_1822219_-\|AlpA-family-transcriptional-regulator	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	1.48799e-20
NZ_CP011636.1\|WP_047723068.1\|1817818_1818340_-\|PTS-glucitol/sorbitol-transporter-subunit-IIC	gnl\|CDD\|226253	COG3730, SrlA, Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism].	8.42382e-79
NZ_CP011636.1\|WP_052959012.1\|1811963_1812527_+\|6-phospho-3-hexuloisomerase	gnl\|CDD\|132171	TIGR03127, RuMP_HxlB, 6-phospho 3-hexuloisomerase. Members of this protein family are 6-phospho 3-hexuloisomerase (PHI), or the PHI domain of a fusion protein. This enzyme is part of the ribulose monophosphate (RuMP) pathway, which in one direction removes the toxic metabolite formaldehyde by assimilation into fructose-6-phosphate. In the other direction, in species lacking a complete pentose phosphate pathway, the RuMP pathway yields ribulose-5-phosphate, necessary for nucleotide biosynthesis, at the cost of also yielding formaldehyde. These latter species tend usually have a formaldehyde-activating enzyme to attach formaldehyde to the C1 carrier tetrahydromethanopterin.	2.11945e-81
NZ_CP011636.1\|WP_047723062.1\|1812550_1813186_+\|3-hexulose-6-phosphate-synthase	gnl\|CDD\|132172	TIGR03128, RuMP_HxlA, 3-hexulose-6-phosphate synthase. Members of this protein family are 3-hexulose-6-phosphate synthase (HPS), or the HPS domain of a fusion protein. This enzyme is part of the ribulose monophosphate (RuMP) pathway, which in one direction removes the toxic metabolite formaldehyde by assimilation into fructose-6-phosphate. In the other direction, in species lacking a complete pentose phosphate pathway, the RuMP pathway yields ribulose-5-phosphate, necessary for nucleotide biosynthesis, at the cost of also yielding formaldehyde. These latter species tend usually have a formaldehyde-activating enzyme to attach formaldehyde to the C1 carrier tetrahydromethanopterin. In these species, the enzyme is viewed as a lyase rather than a synthase and is called D-arabino 3-hexulose 6-phosphate formaldehyde lyase. Note that there is some overlap in specificity with the Escherichia coli enzyme 3-keto-L-gulonate 6-phosphate decarboxylase.	1.14805e-95
NZ_CP011636.1\|WP_071846078.1\|1829192_1829816_+\|DUF4433-domain-containing-protein	gnl\|CDD\|373093	pfam14487, DUF4433, Domain of unknown function (DUF4433). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 201 and 230 amino acids in length. There is a single completely conserved residue E that may be functionally important. This family is distantly similar to pfam01885 suggesting these may be ADP-ribosylases.	1.59168e-25
NZ_CP011636.1\|WP_047723067.1\|1817447_1817822_-\|PTS-glucitol/sorbitol-transporter-subunit-IIA	gnl\|CDD\|226254	COG3731, SrlB, Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism].	3.35424e-57
NZ_CP011636.1\|WP_047723073.1\|1825917_1826796_-\|hypothetical-protein	gnl\|CDD\|236757	PRK10767, PRK10767, chaperone protein DnaJ; Provisional.	1.13773e-08
NZ_CP011636.1\|WP_047723075.1\|1827618_1828866_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	3.1447e-144
NZ_CP011636.1\|WP_047723066.1\|1816470_1817451_-\|PTS-glucitol/sorbitol-transporter-subunit-IIB	gnl\|CDD\|226255	COG3732, SrlE, Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism].	2.25965e-172
NZ_CP011636.1\|WP_047723069.1\|1818711_1819122_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.38134e-07
NZ_CP011636.1\|WP_013815099.1\|1822646_1823615_-\|IS5-like-element-IS903B-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.29527e-57
NZ_CP011636.1\|WP_077258100.1\|1824551_1825325_-\|hypothetical-protein	gnl\|CDD\|368573	pfam05708, Peptidase_C92, Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family. Amidase_YiiX is a family of permuted papain-like amidases. It has amidase specificity for the amide bond between a lipid and an amino acid (or peptide). From the structure, a tetramer, each monomer is made up of a layered alpha-beta fold with a central, 6-stranded, antiparallel beta-sheet that is protected by helices on either side. The catalytic Cys154 in UniProtKB:Q74NK7, Structure 3kw0, is located on the N-terminus of helix alphaF. The two additional helices located above Cys154 contribute to the formation of the active site, where the lysine ligand is bound.	1.42991e-06

>NZ_CP011636.1|WP_148675610.1|1819172_1819445_-|hypothetical-protein
MSSHPEKYAQFLSNLTEVKISHELEAGSKISCILITDIIYAVITIGFALEAPGITLAYGRYHSGEWSTQEISKSIMAIVDASLTNWQKNQ
>NZ_CP011636.1|WP_047723069.1|1818711_1819122_+|helix-turn-helix-domain-containing-protein
MDKTENKNREEDHKIQFGRRLAQAMLLTKHTNASLAQKIGVSEPMVKKYVDGQNLPKADVLLKIARATGISTAWLLEEQEDTQTPEDSAEKDLEFLNDMFKFLSAMQRKIVLKQVSETVAKLLEQEGKYLEKRKRD
>NZ_CP011636.1|WP_047723068.1|1817818_1818340_-|PTS-glucitol/sorbitol-transporter-subunit-IIC
MWTVSLAEAFIHVFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTVRMEKVAALLGRSRILTYGVLPVLGWFFMSSPGALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITEYLFLRLSRRGNAP
>NZ_CP011636.1|WP_047723067.1|1817447_1817822_-|PTS-glucitol/sorbitol-transporter-subunit-IIA
MMIYCARITAIGLFVADGLTDKMLITFDSNGPKDCLDYSLSLEPSFREESLMILPGDRLMLAGHDYLVTAVGKGAQQALFELGHLTLVFNGDLNPCHVGAVHLSGPVPNLRDLHGNLVIEEGRP
>NZ_CP011636.1|WP_047723066.1|1816470_1817451_-|PTS-glucitol/sorbitol-transporter-subunit-IIB
MNTVLIPPGPGGYGKGLWLPVGSGKKVLSLTGREIHPVAIEIGALTQSEIVNGFADIPPDNDILCVVINCAGSLRCGLYPQKGIPTINVLPTWRAGPLAHFITEENYVSGVTMEQLVLVDTAEAPDGRPEATTAPAPRVITAPPPPRGAEKLVRMVEQTGTAVGHVIALLFAASREAVDVSLRNVIPFMAFVSLLIALVQETALGSLIAHALTPLANSLWGLVLLSLICGIPLLSPVLGPGAAISQVIGVMIGTQIGAGAISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGVPAFLLSRQLTGPLAVITGWLFSLGLY
>NZ_CP011636.1|WP_047723065.1|1815437_1816460_-|Gfo/Idh/MocA-family-oxidoreductase
MNKIRAAVVGAGIYGKHHMNAYRHNPDTVLVAICDTDTERCDDLAMAYGVIGYTRLDVLLQEEAVDVVSVATPDPYHTESILTALRHGKHVLAEKPLATSVRECELIVEMAQQRDLLVGVDFHKRWDPAVMRIKAELEKPEAGRILRGHISMDDVISVPTEWLNWAGASSPVWFLGSHCFDLVRHLSGQEVVSVYAVGQKRLMAECGLDTFDSVQSLLTMADGSSWVVENSWVLPEGFPKDNDGRIDILCEATYIRSTSQHRGLEITTPDKTLTPNSYFINYRNGVASGFGIDPINDFVRAVRHKAPYPVTAVDGLAVSRICEAVHRSLESGKPERPIKL
>NZ_CP011636.1|WP_047723064.1|1814445_1815078_-|hypothetical-protein
MNSPIKLCFKCAELYVGEKCHFCGEACPDDYDAVLERSEYAYEMGVKYRQFFEEQVKSNGKVNCFASLIPSEQWLIFIGVAALSGVIGNATYDLVKVIIKNIIEKAKKEGANEIAEKYDSDEKIEILIVQINEYINFPEKIHPEVLRGIKEEERVDDYMYGYSEIMEIKGNINISSEEVEEKIKKIKSRKSKIKSIDEKNFAHFWDNFKK
>NZ_CP011636.1|WP_047723063.1|1813366_1814167_+|hypothetical-protein
MLSTLPDLHRSFAEQLKLKFQSDSRIHSLLAGGSIIHGGFDKYSDLDFIVVVDPLHYDEIMTQRREFAGTLGHLLHAFTGEHVGEPRLLICLYGPELLHVDLKFVTLEMLNQRVEEPAVLFTRDNLALERQLAKFSAHWPNMTPEWFESRAWIWLHYAVVKLGRGELFEAMGMLAFFREQVLGPMLYRRANLPQRGVRRIEFHGIDPDGLLTSTLATHDRDSVSMAIRMAVDAYINLRADALPENIADDAARWVVLTMLKEYSDRG
>NZ_CP011636.1|WP_047723062.1|1812550_1813186_+|3-hexulose-6-phosphate-synthase
MKLQLALDELTLPEALAFIDKVVDDVDIIEVGTPFLIREGVNAIKAIKEKYPHKEVLADAKIMDGGHFESQLLFDAGADYVTVLGVTDVLTIKSCILAAKEAGKQVVVDMICVDDLPARVRLLEEAGADMLAVHTGTDQQAAGRKPIDDLITMLKARRKARIAVAGGISSQTVKDYALLGPDVVIVGSAITHSADPAGEARKISQVLLQHH
>NZ_CP011636.1|WP_052959012.1|1811963_1812527_+|6-phospho-3-hexuloisomerase
METQSVAGVACTDLHQAMARIDGAALARLEQAIAEANAVFVFGAGRSLLMLKAFAMRLMHIGLTVHVVGDVVTPALQKGDLLLLASASGETTSLVNVATKAKQLGGTVALLTIFPESTLGKLADVVVRIPAYTDKLPDGPENVKGILPGGSLFEEAVMVLGDAMIVNLAQSTGYRLTKGFALHANLE
>NZ_CP011636.1|WP_047723070.1|1819898_1821968_-|DUF927-domain-containing-protein
MKRAPFLNKQSPDRTLEVVILAGSLAWETSRAWRKDPDREDDVPPVVLGPDELADLDNLTIIRPDTLYVRVLRIGDIREEELLKIAVKLAHADVQIARLMSPDGELLENWSGQLARLRQERPSDILPDHFRLDEEALWFDKLTERRDGESDVQPQRISSPLRVTAITCDSHDGSYGRLLEWHTTTGQLRRWAMPMAMLSGNGEELRRILLENGLTYISTRPALRSLLCEYISRSLPGRRVTCVEKTGWHNGVYVLPDEVIGPGGDNVILQGSHYLTGGFAQAGTLAEWQELVAALCAGNSRLVFALCCALAAPLLRLTGTGGGGFHLRGESTDGKTTVMKVAASVCGGTDYWHSWRATGNALEGIASRHNDALLPLDELREVDPREAGMIAYMLANGQGKGRARTDGEVRNRRHWTLLLFSTGELSLAEHTERAGERLYAGMDVRMVQIPSDTGQHGAFEQLHGFASGQQFADALCDRVARFHGTAFRAWLVFLTHDQDDNIALAKELLRRYQTALMPENAGNQVQRIVARFALLAVAGEMATLHGITGWQEGTAYEAVQICLRAWLNERGHIANQEDEGVLAQIKRFITAHQYSRFASWDGPDRPLNMVGFRRVEKDPLTGEEHTLFHILPEGWREMCRGFSPARAARLCQEAECLLPGSDGKYQSQVRLPEIGKARVYRLTSRILSI
>NZ_CP011636.1|WP_047723071.1|1822003_1822219_-|AlpA-family-transcriptional-regulator
MKTRADSNDAFPESGNVRMRQVVQFLAMSESSVYRLIKNTDFPRPVHLSSRLVVFDAAEIRQWQQRRAAIR
>NZ_CP011636.1|WP_013815099.1|1822646_1823615_-|IS5-like-element-IS903B-family-transposase
MKDQITYLPDNADRSVAKQKFKITNWPTYNKALINRGSITFWLDDEAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFSLMNVPLRCPDYSCVSRRAKSVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRKLHLAVDSKTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRAASADGAYDTRLCHDELRRKKISALIPPRKGAGYWPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETAMYRVKQLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA
>NZ_CP011636.1|WP_077258100.1|1824551_1825325_-|hypothetical-protein
MNAGDIILINNGTWYNIFLQKSLRKKSSVNATHVALSLGEGAFIHADTSCGVGFAYFPDLLVDSKGRWKVIRNKEINSDFEEKIEKAGIFHFNKTYNYGFLLKENEKSLFCSQLVDLVYKSVGVDIFGRNKTKSLLNLNNAFPVDFEELLIKDERWCEVSNVYQDNLNSGFIELQRTNFLMRQALIMSERNTRKFHSDMLDLVNTLNESHNLLPKEFKSTELETHLSEMITGLNESESAFFYNFWNIRSNKNRQVRS
>NZ_CP011636.1|WP_047723072.1|1825562_1825757_-|hypothetical-protein
MKNANPEHYKSLALIASAEDAVNKNDVTGAKQYLKGVMKWCVDVSTKIDVNVATEFIKSSMGVK
>NZ_CP011636.1|WP_047723073.1|1825917_1826796_-|hypothetical-protein
MELDETLEVIKNNFSNNQKKLLKRIEPATNRQVAIGLISLQGVEKTSQAEIEVIASLISQFSPLEIDNFQNSPRRITLKGQFPNGHIVYIEPQYKVGNINPKAQPWAIDLVLRLNRWIGQDLVEIAAIGIEYDGHIAHYVESKIKSTYKRDAIITSNEGFQSLRISPEQWKSSKEDLKKAIKKYFEHHIKKIEKVQLSTINAQDFNKFIYENENKNEVISTVTCPLCNGRGSLAGEDCPICNGMGSVKRYIAAKVNLSNYEKFTCPDCRNIKLDCRTCNGEGSISREKALEM
>NZ_CP011636.1|WP_047723074.1|1826972_1827617_-|hypothetical-protein
MTSPIRQNLFERECDMPLLEARHLALLLLGLDASQPANALPEEHQENYRILHDAISRTIKATGMVSAPANKRMFYADEMFALAWRLIDDELTPPEIKARSLKAVMKLSRNSRGRKWLKTLGDDALPDLTASAQPSLRGMHKRDKARENTARLCWLLVQLLVEETDGRYGTSDKPASDRILRKLKTLAQERGLSFDGLGRGTFYEVLKMGKEKET
>NZ_CP011636.1|WP_047723075.1|1827618_1828866_-|tyrosine-type-recombinase/integrase
MPKQLKPLTNVEIAGAKPRSTDYELRDGEGLYLLVKTSGRKAWHFEYYHPVTKKRTKTSLGPYPVVTLAMARETRTKYRRLLWQGIDPRQHLAGIAEEKRIQNECTLEKVAEQWLKEKKRTSDLSEDHAKDIWRSLEMHVFPSLGSTPVTEIRPKMLKEHLTPLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCLIEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQVMEPVSRHRPWVFPSIRKPLEHMHQQTANAALIRMGFGGELVAHGMRSIARTAGAGHFPREVLESALAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQALLGAEEPLRIVEGE
>NZ_CP011636.1|WP_071846078.1|1829192_1829816_+|DUF4433-domain-containing-protein
MTIQEIVQQRNITKLFHFTHSDNLSSIIESGLLSRSDLDDEGDNYDFNDSERIDGHLDAICLSVSFPNARMFYKYRNLKPGSWVILEIDPSVLWTKNCAFYPTNAASNNVRFNDLELMKGAKAFSALFANEVYGTTRDDYLTAQYTTDVQAEVLVFEKIEPSYIVAYLHPNKDSYQPFKDQYPKTNQRYYANLNGKTLFSQRHYCLG
>NZ_CP011636.1|WP_047723077.1|1829819_1830509_+|hypothetical-protein
MAVRPIFVPTNSGHVLSITKDVDFPWSPGMSKSQKQKSIRALHSAANGLGLNSLLEISSKSEDALGVELSAFNLIIKTKKLGKEFSVESAFQASKVFEAGGPFVDILDKTSIEAKKDIRLKESGGLVSFNFYNTTWPLVPRTAFYDWLYLSALNQNKKLAMHLLNFDGFTDIEFNPAKSINCQARTAALFVSLVKRNMLEKVLSSQSEFLSVLASHYGVESYSVQNVLI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP011636_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011636_3

3307641-3307766

Orphan

Consensus_repeat	Method
AACCCGGGGAATATGCCGTGACGGGGTATTGCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011636_3

>merge|NZ_CP011636|3|3307641-3307766|CRISPRCasFinder
AACCCGGGGAATATGCCGTGACGGGGTATTGCTGTGGCTTCTTCCCGGCTTGCGCTGCGCTTAGCCGGGCTACCGGGCCGCAGATTGCTGGTAACCCGGGGAATATGCCGTGACGTGGTATTGCTG

>NZ_CP011636|3|3|3307641-3307766|CRISPRCasFinder
AACCCGGGGAATATGCCGTGACGGGGTATTGCTG	TGGCTTCTTCCCGGCTTGCGCTGCGCTTAGCCGGGCTACCGGGCCGCAGATTGCTGGT
AACCCGGGGAATATGCCGTGACGTGGTATTGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011636.1\|WP_047723781.1\|3311885_3312707_+\|homeodomain-like-domain-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_032749054.1\|3304399_3305188_+\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|223422
NZ_CP011636.1\|WP_047723777.1\|3303631_3304387_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP011636.1\|WP_025106265.1\|3313437_3314247_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NZ_CP011636.1\|WP_047723782.1\|3314271_3315228_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238568
NZ_CP011636.1\|WP_032749050.1\|3300807_3301506_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP011636.1\|WP_047723783.1\|3317499_3317976_+\|WbuC-family-cupin-fold-metalloprotein	unknown	unknown	gnl\|CDD\|275159
NZ_CP011636.1\|WP_009652191.1\|3309454_3310408_-\|N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	unknown	unknown	gnl\|CDD\|271335
NZ_CP011636.1\|WP_047723779.1\|3307993_3309451_-\|leucyl-aminopeptidase-family-protein	unknown	unknown	gnl\|CDD\|238247
NZ_CP011636.1\|WP_032694933.1\|3303104_3303644_+\|L-2-amino-thiazoline-4-carboxylic-acid-hydrolase	unknown	unknown	gnl\|CDD\|372958
NZ_CP011636.1\|WP_047723775.1\|3298315_3298525_-\|DUF1471-domain-containing-protein	unknown	unknown	gnl\|CDD\|369322
NZ_CP011636.1\|WP_038424548.1\|3301515_3302268_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP011636.1\|WP_047723780.1\|3310412_3311732_-\|PTS-cellobiose-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
NZ_CP011636.1\|WP_014838552.1\|3306249_3307449_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|182309
NZ_CP011636.1\|WP_000019450.1\|3299331_3300312_-\|IS5-like-element-ISKpn26-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP011636.1\|WP_004851091.1\|3312818_3313148_-\|NIPSNAP-family-protein	unknown	unknown	gnl\|CDD\|311781
NZ_CP011636.1\|WP_047723776.1\|3302257_3303100_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270428
NZ_CP011636.1\|WP_004851083.1\|3315224_3316232_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP011636.1\|WP_014229447.1\|3316662_3317169_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047723778.1\|3305184_3306141_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378976

Protein	Function_ID	Function_description	E-value
NZ_CP011636.1\|WP_025106265.1\|3313437_3314247_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	1.32008e-75
NZ_CP011636.1\|WP_032749054.1\|3304399_3305188_+\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|223422	COG0345, ProC, Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism].	1.69706e-57
NZ_CP011636.1\|WP_047723777.1\|3303631_3304387_+\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	2.6353e-33
NZ_CP011636.1\|WP_047723782.1\|3314271_3315228_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238568	cd01148, TroA_a, Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.22067e-132
NZ_CP011636.1\|WP_032749050.1\|3300807_3301506_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	7.75323e-44
NZ_CP011636.1\|WP_047723783.1\|3317499_3317976_+\|WbuC-family-cupin-fold-metalloprotein	gnl\|CDD\|275159	TIGR04366, hypothetical_protein, cupin fold metalloprotein, WbuC family. Members of this family show sequence similarity to cupin fold proteins (see pfam07883), including conserved His residues likely to serve as metal-binding ligands. Many members occur in bacterial O-antigen biosynthesis regions. Some members have acquired the gene symbol wbuC (e.g. Jarvis, et al, 2011), but publications using this term do not ascribe a function.	1.48615e-62
NZ_CP011636.1\|WP_009652191.1\|3309454_3310408_-\|N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	gnl\|CDD\|271335	cd04513, Glycosylasparaginase, Glycosylasparaginase and similar proteins. Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU). The glycosylasparaginase precursor undergoes autoproteolysis through an N-O or N-S acyl rearrangement of the peptide bond, which leads to the cleavage of a peptide bond between an Asp and a Thr. This proteolysis step generates an exposed N-terminal catalytic threonine and activates the enzyme.	4.42413e-117
NZ_CP011636.1\|WP_047723779.1\|3307993_3309451_-\|leucyl-aminopeptidase-family-protein	gnl\|CDD\|238247	cd00433, Peptidase_M17, Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and play a key role in protein degradation and in the metabolism of biologically active peptides. They do not contain HEXXH motif (which is used as one of the signature patterns to group the peptidase families) in the metal-binding site. The two associated zinc ions and the active site are entirely enclosed within the C-terminal catalytic domain in leucine aminopeptidase. The enzyme is a hexamer, with the catalytic domains clustered around the three-fold axis, and the two trimers related to one another by a two-fold rotation. The N-terminal domain is structurally similar to the ADP-ribose binding Macro domain. This family includes proteins from bacteria, archaea, animals and plants.	3.899e-137
NZ_CP011636.1\|WP_032694933.1\|3303104_3303644_+\|L-2-amino-thiazoline-4-carboxylic-acid-hydrolase	gnl\|CDD\|372958	pfam14196, ATC_hydrolase, L-2-amino-thiazoline-4-carboxylic acid hydrolase. This family of enzymes catalyzes the conversion of L-2-amino-delta2-thiazoline-4-carboxylic acid (L-ATC) to N-carbamoyl-L-cysteine. It cleaves the carbon-sulphur bond in the ring structure of L-ATC to produce N-carbamoyl-L-cysteine.	2.03311e-08
NZ_CP011636.1\|WP_047723775.1\|3298315_3298525_-\|DUF1471-domain-containing-protein	gnl\|CDD\|369322	pfam07338, DUF1471, Protein of unknown function (DUF1471). This family consists of several hypothetical Enterobacterial proteins of around 90 residues in length. Some members of this family are annotated as ydgH precursors and contain two copies of this region, one at the N-terminus and the other at the C-terminus. The function of this family is unknown.	0.00023301
NZ_CP011636.1\|WP_038424548.1\|3301515_3302268_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.28462e-57
NZ_CP011636.1\|WP_047723780.1\|3310412_3311732_-\|PTS-cellobiose-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	5.51167e-136
NZ_CP011636.1\|WP_014838552.1\|3306249_3307449_+\|MFS-transporter	gnl\|CDD\|182309	PRK10213, nepI, purine ribonucleoside efflux pump NepI.	2.69153e-108
NZ_CP011636.1\|WP_000019450.1\|3299331_3300312_-\|IS5-like-element-ISKpn26-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	7.00081e-54
NZ_CP011636.1\|WP_004851091.1\|3312818_3313148_-\|NIPSNAP-family-protein	gnl\|CDD\|311781	pfam07978, NIPSNAP, NIPSNAP. Members of this family include many hypothetical proteins. It also includes members of the NIPSNAP family which have putative roles in vesicular transport. This domain is often found in duplicate.	6.50464e-05
NZ_CP011636.1\|WP_047723776.1\|3302257_3303100_+\|extracellular-solute-binding-protein	gnl\|CDD\|270428	cd13710, PBP2_TcyK, Substrate binding domain of an ABC transporter TcyJKLMN; the type 2 periplasmic binding protein fold. This group contains periplasmic cystine-binding domain (TcyK) of an ATP-binding cassette transporter from Bacillus subtilus and its closely related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.04008e-53
NZ_CP011636.1\|WP_004851083.1\|3315224_3316232_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	3.4964e-76
NZ_CP011636.1\|WP_047723778.1\|3305184_3306141_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	4.99318e-28

>NZ_CP011636.1|WP_014838552.1|3306249_3307449_+|MFS-transporter
MSSCIAAEESQANARPAWRAVYALALGVFGLIVAEFLPASLLTPMAASLGVSEGMAGQAVTATALVALVTGLLITTATRNIDRRWVLMFFSVLQIISSMMVAFAGSLEFLLLGRLLLGIAIGGFWSMSTATTMRLVPAAMVPKALAIIFSAVSIATVVAAPLGSYFGALIGWRNVFLICALPSVVALLWQLWVLPSMRPESVGSFATLFKVLRRPGMIGGMLATILIFSGHFAFFTYLRPFLETVAQASVEGVSLILLGFGVANFIGTSIAGHLLARSLRLTLALVPLAMSVLALMMVTFGHVALLDGLLVAMWGFAFGLVPVGWSTWLATTVPDEAESAGGLLVASIQLAISAGAAGGGAVFDLNGASGVFVGSGVLLVSAMVIVLFAVRVKPVVSEE
>NZ_CP011636.1|WP_047723778.1|3305184_3306141_-|AraC-family-transcriptional-regulator
MTQHALDLTSELLRGMRLSGVNYRRIETSRPFGVEFGFVPGKAQFHFISRGPVLLRMVSGQRLMLQSGDALFIPNGDGHVLLSDDQATVINVSRLPSEPVCGSVSCVKNACDDAKSDSAIIFSACMDFELGGMQPLVKAMPEVMLVSSLLTSRPEIPPMLAAMERESLTRQAGYAGILARLADVVAALIVRGWVECGCGNATGWVQVLRDPKLAKAIYVMHQQPGINWKVEDLAREAGISRSVFAERFLSATGTTPARYLTELRMRLAVQYISHEGQALEKVAFRLGYSSHAAFSRAFKRIIGKAPGALRDLSREEGF
>NZ_CP011636.1|WP_032749054.1|3304399_3305188_+|NAD(P)-binding-domain-containing-protein
MTRVHFFGAGQMAEAIIRASLSHGALRADAISLEDIDSARVEALRARYRLSGDGGVNEAALLVLGIRPQDDLAGVANRVRPQLNGSTTVVSLIAGVTLEKLASLFGAATPIARAIPNTLTDTGFGYSGVTLNPHASAAEIEPFLRGFGKVLYLPERLIDIFTGFGVAGPNYIYYFIESLTDAGVLAGLPRPQATEVVLENLLGAVEMLRQSQKHPRQLLDINNSPAGVGIHGLYELNNSDFAAGLQRSVLAAVRRTRELGQC
>NZ_CP011636.1|WP_047723777.1|3303631_3304387_+|VOC-family-protein
MATLTWDHAVQFVNQPEAAIQALSGQKLNAVAGGRHPGWGTRNALSYFGLTYIEFLAIADDAELLSAAETFLLCRDASRLLPDNEALYRVALRSDDIERTHAELHEQGLRVSPIVNGQRDDPQGNVIRWRIFTIDGDFDGLVYPFILQWGEEDDARLSRLQAQGLAAPHPLGEIELQRAVFTVQHPQAVRDRWQLLFGFAPQGEQGLAVGGREFLFRQGAANQLTELVFRVADPALKGRRFRVGNGEYLFE
>NZ_CP011636.1|WP_032694933.1|3303104_3303644_+|L-2-amino-thiazoline-4-carboxylic-acid-hydrolase
MTQISSEPAHNAATLNDEVTLALRAITEKRAATIGYLLDESRQRHIADDSVREAIRHYGRDIGHKLRAQMRDRKDLQEFAGLFTRGLESQVYEMEPVSASRAEFIVLFHYCPYVNCWRQQGRGASEIETLCDICMEGDRALTDAFPGLHLEVQTALARGDAACRLRFYQAEEREGEWQP
>NZ_CP011636.1|WP_047723776.1|3302257_3303100_+|extracellular-solute-binding-protein
MKNKILLVSALTLAIGMNAAQAVEKSPNAKTVEVVVNANGFPFSFVDDNNNITGYDGDLLKVLDQRLTDYTFHFNAVSRDAMIVGLSTGAYTLAADHFYLTKERAEKYDHSGEPTGISDLCLIVRNDENDIHNLGDLASGKKKLVPIHTSDARYTVIENYNKKHPGQQINLQPNGEQSAADIFKAVASGEYDAAIYPIGALLELNKALNLNLKASDSVGLFPNVYLYKKNTDPQLIKAIDAQLVALKKDGTLAELSRKWYAEDVYALPGASDVKVNTDWE
>NZ_CP011636.1|WP_038424548.1|3301515_3302268_+|amino-acid-ABC-transporter-permease
MFSLAFIRDNFTFILSALPVTLTITLLSLLFSTLLGAALAWAIIRQVPGVQWLARVFLSFGRSVPVLVMLYFFFYVWPWIAAGLFGGPQDTMYRYKLSPLAAAVTALSLIFSAYFAETFRAGWNAVDKGQREAAWSIGLSGFTQFRRIIFPQAAVSALPNFTSVLIDLIKDTSLVYTITVVDLMAKANIAAARGFHFVEAYCVVLVIYIVLCLAIARALRSAERFLSARWQGNAEKSVSRLSFWGRYFEK
>NZ_CP011636.1|WP_032749050.1|3300807_3301506_+|ABC-transporter-permease-subunit
MNNNPLFSWPDIAGIVPKLLENLPVTLGITLASLLLGLTIALLIVLLQFSRFRPLSAAANGYTDILRGAPLALLILLFFFGGKLILTALALPPLWISDTTFAVLSISVSISPYFAEMMRSAWRAVDSGQKEAIISLNIPWHQGIRRIIFPQGLIIAIPVFGNLLINLVKMTSLVNIIGIVDVFGRAQKISQNSYGAKQVAAFISVIIVYWVLNSIILYFTTRIEKKYQFLLE
>NZ_CP011636.1|WP_000019450.1|3299331_3300312_-|IS5-like-element-ISKpn26-family-transposase
MSHQLTFADSEFSTKRRQTRKEIFLSRMEQILPWQNMTAVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGRVKTLKQHPRKNKTAINIEYMKASIRARVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRVDQMIRQWERSQ
>NZ_CP011636.1|WP_047723775.1|3298315_3298525_-|DUF1471-domain-containing-protein
MKSIKTFVAVTALSMISFGTFAQSISASASTLDRAEAKIAAQAAEQGASYKITSAQFNNRVHMTAELTK
>NZ_CP011636.1|WP_047723779.1|3307993_3309451_-|leucyl-aminopeptidase-family-protein
MLDYRLINQLDSDCTGAHLVTWPGSTLLAQAPLNAVPLLAEMVEQAARGEVADTRFGCSPFARITLIPPPLWRDTLNDGLAEALRPLCKKPVSETLILDASLEESSGALTKALRELFNLDWQLDDLGLHQVKAARPRLRQLALYALPEQRSALDTLAHRQRATAHGMLAARRLADLPAEQCTPQYVVEEARRLCADIRTLRCEVLDEKAIVEQGLGLLHAVGKGAERPPRLLAIHYDGVSEGPVRCYVGKGVTFDTGGLWLKEGAGMYTMKYDMCGAANVLGLMLSIAELALPVRVMGVLALAENAIGPAAMQPGSVARACNGLTVEINNTDAEGRLVLSDAIAWASQRYPQAHYIIDIATLTGAVVKALGYDLSGLMTQSDALRAGLTRAGIKSGDEVWSLPLDSRLKKQTESAIADLCNTPGNNAAISASAAWLLHHFCPPEIPWAHLDVSGTALWREGGKSVASGRPIPLLIQHLLDDIDES
>NZ_CP011636.1|WP_009652191.1|3309454_3310408_-|N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
MWGMIATWRMALEGVTEAAAALASGADTASAVVNAVAAVEDFPLYKSVGYGGLPTENGEVELDAAFMHGDTLAFGAVGNLVDIANPVKVAHALSRQRYNSLLVGQGAREWAISQGFAAKAMLTERAMQHYRKRCRETLDKGLSPYDGHDTVGIIGLDKQGSMSVATSTSGLFMKKRGRLGDSPIIGSGFYCDSETGAATATGVGEDLMKGCTSYEIVRRMAQGMTPQQAADSVVCELEDKLMSRFGRAGDLSVVCMNRRGEFGAATNIKTFSFVVASATQPLTVFCAERVREKTHYRPVDDEWMQAYAARIRAPIEE
>NZ_CP011636.1|WP_047723780.1|3310412_3311732_-|PTS-cellobiose-transporter-subunit-IIC
MNNVLGFLEAKLMPLAAKTAQQRHLGAIRGAYVSFMPFIIVGSILLVISSFPNQSYQQFMASTFGASWSAIIEIPFNAVFSTMSLFISFLVAYRLAEHYGDDRISCGILSLVGFLILTPFIKVAENGGITVIPVEWIGTKGLFVAMIGSLLWTELFCWLKRKKLVIKMPDGVPPAVQESFAALIPALLVMILILAIRIGFAHTHYATIHQFIYEVVASPVRHYGTSYFGALMTVFSITILWSVGINSGSMINGIIRPLWMENQTDNIAAIQAGVTPPHIITEQFFDMIWMGGAGATLSLVIAMLIFARSKNMREVARLGAGASIFNINEPILFGLPVIMNPIMLIPFNLVPLVLVTVQYAAMKIGAVAVTTGVFIPWTLPPVISGFIVTGHLSGSVMQILNLLIGAMLYLPFMRIVDKQYRAAEVTASAETDNTLAKQE
>NZ_CP011636.1|WP_047723781.1|3311885_3312707_+|homeodomain-like-domain-protein
MEIKLHANATTTPRTRKYLQESTKSDRELAQELGISITTVRRWRNRSQISDKHTTPHLIHKVLRQEQEILINALRDALRSPLDELLFMVNEGLGIAISRATLNRYLRPAHEGRKNAALQGKKALKAGMRADTLTLHYRQLALSMDDGGEHHLLWAQEPISGWCFGRIYSGISPSLVDSWLTEALNACPARIQCLEIYAHKGFQPARADLSCRTVAMAERGAVQLSERLADVIPALDEPDATLQRLCALWNRGRAQKKLGDTTPKGFLESLNQN
>NZ_CP011636.1|WP_004851091.1|3312818_3313148_-|NIPSNAP-family-protein
MKTVEFLLYTLKPGTGNEFHRIMKEQSAPCHRAAGMDIVSFGNSVDDNDAYYLIRAYEDLTHLNASQAHFYSSPAWREGPRQAIIDRISVSVKTVMLLSDSAIDGLRNG
>NZ_CP011636.1|WP_025106265.1|3313437_3314247_+|ABC-transporter-ATP-binding-protein
MEESLTKSGKADDPVLSVNIASLPRPGGGEMLSGIHFSAGKGECLAVIGPNGSGKTTLLRAIDCQLPSREGDVRLYGRSIAALTRQQRARQIAVLAQNDTPDLRLALEDYVALGRIPHARDMSRREHDIIVTRAINDTGLQRLRKRPLSALSGGERQRAALARVLAQAPKLLLLDEPTNHLDPHGRVELLSLVKSQGITVVAVLHDLSLIDAFADRVLLLSQGRAVAWDVPERVLVSQRLYPVFGLTSFTVPHPMTGKALRIFEVPGYA
>NZ_CP011636.1|WP_047723782.1|3314271_3315228_+|ABC-transporter-substrate-binding-protein
MNKWFAGTMAFLFISAANAADFPVTIDSCGTPVTFTQAPKRAVIHDLNMSEMAFALGLQDRIVGLTGITGWYKMTPEFKHQMGSIPELAPKYPSLETLLAANPDFFFAGWNYGMKVGGEVTPSVLETYGIKTFVLSESCVFTASQKQKASMDLLYNDELTLGKIFGKQHEARTLVDGWKKTLNALPKPPQGVQPLKVFVYDSGEDKPFTSGRYAMPTAIIEAAGGKNVMDDLEMSWGTTSWESVATAEPDFIILLDYQTGSGADSLRRFLENHPLMKQTPAVKRQRYLKLQYAELTPGPANINAVEKLAHAMYPAAHQ
>NZ_CP011636.1|WP_004851083.1|3315224_3316232_+|iron-ABC-transporter-permease
MSGTHCRYYWAAWGALPLLAGLMLLSVAKGSVPLSLTQVLGALRLLDVPVSEMIGRIVIDLRVPRTLLAVLAGAVLAIVGGLLQTTTRNDLADPFLFGLSSGASAGAVLVITRFGERLGALTLPVSAFVGGICSAVAVMLLFHFKKQRGAEHLVICGLAISFLFGALTSYLIFSGDQRAASSVLFWSLGGLGLARWDNLPYALFSLLLLGAFILLRWRSLDGLLAGEQTAQSLGINVTRLRMEVFFCCALATSLLVALTGVIGFIGLMVPHMCRYFSGVKHLLLLPLCGLWGAVLLCGGDIVSRTLLAPQELPIGIITAGIGGLFIIILLARNRS
>NZ_CP011636.1|WP_014229447.1|3316662_3317169_+|hypothetical-protein
MLTIFSHNHFFKKAIRLKINDIKAVRKANLVDLCLTKYASSSCAQFHFLINSFEMKKNFVCFRVEGNIICLINKRRTAHIASIIARVTDGIPVGEDITLTEREFQYIFIMKFTVLAKDYPELLGISPKAYSSYKRRLIEKFGFNSFHALLALSNYLHAFSLLDKFTPD
>NZ_CP011636.1|WP_047723783.1|3317499_3317976_+|WbuC-family-cupin-fold-metalloprotein
MKQMTLSDLRQQSEQAAASPRLRAHRNFHPDLSDPVQRLAVAMEPGTYVRPHRHPHTFELLTSLSGRFVVLTFDDAGNVTERVVLGEECKALEMAAGTWHAVLSMDKGGVIFEVKYGGYQPVSEQDAAPWAPAENAPGTAELMKWYARAQVGDGGFTL

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Crispr_ID: NZ_CP011636_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011636_4

4437489-4437571

Orphan

Consensus_repeat	Method
TGGACACTGGCTGGACATCGGCTGGACA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP011636_4

>merge|NZ_CP011636|4|4437489-4437571|CRISPRCasFinder
TGGACACTGGCTGGACATCGGCTGGACACTCCACCTCCGCAGGCATTGGTATTACTGAGTTTGGGCTGGACACTGGCTGGACA

>NZ_CP011636|4|4|4437489-4437571|CRISPRCasFinder
TGGACACTGGCTGGACATCGGCTGGACA	CTCCACCTCCGCAGGCATTGGTATTAC
TGAGTTTGGGCTGGACACTGGCTGGACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011636.1\|WP_047684208.1\|4438823_4439513_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP011636.1\|WP_047724182.1\|4441935_4442595_+\|exodeoxyribonuclease-X	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|181186
NZ_CP011636.1\|WP_162487899.1\|4440508_4440634_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_187116903.1\|4435655_4437071_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672
NZ_CP011636.1\|WP_047724176.1\|4432482_4432797_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047684213.1\|4438462_4438696_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374243
NZ_CP011636.1\|WP_047724174.1\|4430981_4431626_-\|recombination-protein-NinG	unknown	unknown	gnl\|CDD\|368603
NZ_CP011636.1\|WP_009308001.1\|4434325_4434910_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|379158
NZ_CP011636.1\|WP_047725114.1\|4433766_4434324_-\|ead/Ea22-like-family-protein	unknown	unknown	gnl\|CDD\|379401
NZ_CP011636.1\|WP_019704100.1\|4440626_4440821_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047684216.1\|4438200_4438422_-\|bacteriophage-CII-family-protein	unknown	unknown	gnl\|CDD\|336083
NZ_CP011636.1\|WP_047724173.1\|4430760_4430985_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_162934436.1\|4441798_4441942_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047725119.1\|4434906_4435365_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_004194002.1\|4437967_4438114_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047724177.1\|4433575_4433767_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_071846130.1\|4441409_4441805_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011636.1\|WP_047724180.1\|4439759_4440389_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376179
NZ_CP011636.1\|WP_071846128.1\|4431618_4431789_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP011636.1\|WP_047724175.1\|4431781_4432231_-\|recombination-protein-NinB	unknown	unknown	gnl\|CDD\|368607

Protein	Function_ID	Function_description	E-value
NZ_CP011636.1\|WP_047725114.1\|4433766_4434324_-\|ead/Ea22-like-family-protein	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	1.76965e-10
NZ_CP011636.1\|WP_047684208.1\|4438823_4439513_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	1.57027e-27
NZ_CP011636.1\|WP_047684216.1\|4438200_4438422_-\|bacteriophage-CII-family-protein	gnl\|CDD\|336083	pfam05269, Phage_CII, Bacteriophage CII protein. This family consists of several phage CII regulatory proteins. CII plays a key role in the lysis-lysogeny decision in bacteriophage lambda and related phages.	1.95002e-09
NZ_CP011636.1\|WP_187116903.1\|4435655_4437071_-\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	1.94089e-158
NZ_CP011636.1\|WP_047724182.1\|4441935_4442595_+\|exodeoxyribonuclease-X	gnl\|CDD\|181186	PRK07983, PRK07983, exodeoxyribonuclease X; Provisional.	4.35937e-129
NZ_CP011636.1\|WP_009308001.1\|4434325_4434910_-\|HNH-endonuclease	gnl\|CDD\|379158	pfam13392, HNH_3, HNH endonuclease. This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.	2.43742e-15
NZ_CP011636.1\|WP_047724180.1\|4439759_4440389_+\|hypothetical-protein	gnl\|CDD\|376179	pfam18757, Nmad5, Nucleotide modification associated domain 5. An alpha+beta fold domain associated with DNA base modifying genes in prokaryotes, and likely to be involved in modified DNA base biosynthesis.	8.75255e-48
NZ_CP011636.1\|WP_047684213.1\|4438462_4438696_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	6.66078e-22
NZ_CP011636.1\|WP_047724174.1\|4430981_4431626_-\|recombination-protein-NinG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	3.64286e-53
NZ_CP011636.1\|WP_071846128.1\|4431618_4431789_-\|hypothetical-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	5.88775e-21
NZ_CP011636.1\|WP_047724175.1\|4431781_4432231_-\|recombination-protein-NinB	gnl\|CDD\|368607	pfam05772, NinB, NinB protein. The ninR region of phage lambda contains two recombination genes, orf (ninB) and rap (ninG), that have roles when the RecF and RecBCD recombination pathways of E. coli, respectively, operate on phage lambda. NinB binds to single-stranded DNA.	3.5503e-56

>NZ_CP011636.1|WP_187116903.1|4435655_4437071_-|AAA-family-ATPase
MTPPHSIEAEQSVLGGLLLDDDSSERTQKVLSILKPESFYARPHQVIFAEMRQMYRDHKPVDLLTLFDALESKGLTETVGGFAYLAEMSKNTPSAANIVAYAMRVRETAMERYGIEKTTKAIELLYARNGMTAEQKFDAIQGLFTEITDHVKTGRRTGLRTFYDAVNDWSNEFDDRMKPDGRSRGLSTGIRSLDELLGVKRIVRGSLFVIGARPKMGKTTLYTQMGVNCATVENEPALMFSLEMPEGQMVEKITAQKGRISPNLFYPDMTKDDYGYRGDWNGDLKKATGVMGALIDTNNLLIDDTPGISLAHVMAESRRIKRERGKVGMILVDYLTLMTADKAERNDLAYGLITKGLKTLAKELDCVVVLLTQLNRELEKRTNKRPLPSDSRDTGQIEQDCDYWLAIYREGAYDENANQSDTELLLRLNRHGETGVVYCEQRHGAIYDCDQEAASQRRREKEQKPTKRGGF
>NZ_CP011636.1|WP_047725119.1|4434906_4435365_-|hypothetical-protein
MTITLQAVNELIASLESAGELSIREQKFLKLAKEFRICSASLDAAIKTGNMLADQNAQLAAENVEAKKIISECREYFIAGVMNRIRPTNEGYLHMICDTFADETPATDRIVAEAEARGVEKAIAHLEKKFSNIGVQIMNLQWLADSLREGAK
>NZ_CP011636.1|WP_009308001.1|4434325_4434910_-|HNH-endonuclease
MSKVNHSIAAKPINKEMIETYLHFDGLDFYWKERPLHMFKSEASCISWNKRFAGKKASHTSCKGYQEIRLLGSVYKAHRFVWCMHNGDIPKEMSIDHINHDRSDNRIENLRLVTQAENKRNATVRKDNSSHAVGVHFRRDIRKWTAYIFDGEKKKHLGTFLERKDAESARLNAEKQLGFHPNHGKAKCEAHYDN
>NZ_CP011636.1|WP_047725114.1|4433766_4434324_-|ead/Ea22-like-family-protein
MTELAQSLKAAAEKATTGNWRAFQYHDGRCGVGGGNHDEIMVCEHISKERPHDAMFIALANPANVLALVEALEKAQQRNAELEAQNEYIRKRYQQLDLLIGENILVMQAAIIEWQATGDAKNGLAWIYNTLFGPGELPDEAEKDAQAYFDRKYAPLDEELMALHKWFWEQGEAERAAAGIKVEAE
>NZ_CP011636.1|WP_047724177.1|4433575_4433767_-|hypothetical-protein
MAEKTALERLRKINAENQRRVFVSVGTLKAARSEIQAHIKVNGKGIMTDIVLDQLNKSIGDGE
>NZ_CP011636.1|WP_047724176.1|4432482_4432797_-|hypothetical-protein
MAELRAGCQAMIIGGFYRTNDGKSVLVVGFVPNGSRFTWNGEVYAEPVPMGDAWLVSGDMVARDGDTREAKRMDFALMPAKYLMPIDGDDFSNEDQHQKEREHA
>NZ_CP011636.1|WP_047724175.1|4431781_4432231_-|recombination-protein-NinB
MKQQFHLVNDAIKQNAINFIRELPVDAKRPLILDIKEMTRTLEQNKKMWPLLKDLSDQVVWFGNKYDSDDWKDLITALVAKSKKQEQRMAPGLDGGVVMFGQRTSKMTVRQMVEVIEAIYWFGTQQGVKFSEKSCIEIEWAKRWGESHA
>NZ_CP011636.1|WP_071846128.1|4431618_4431789_-|hypothetical-protein
MHSPLAKVMERSIFRIPSRRKRKAEVKPSDIPTLKGYTARLVDKKWLCLRARRPHG
>NZ_CP011636.1|WP_047724174.1|4430981_4431626_-|recombination-protein-NinG
MAKLPRRKCAYQGCREWFHPMRNGQVVCSFECASAIGKEQTAKAREAAKQKEAQRQRTEEKAGRQRRKAKRESFKTKAQWDKEAQSAFNRYIRIRDDGKPCVSCGNPLIGKSNYLTGSAIDASHYRSRGAASHLKFNVFNVHSACTRCNRQLSGNAVEYRIHLIERIGLDRVERLEADNVSRRFDIPYLQRIKSIFTRRARALEKRRARHQEAA
>NZ_CP011636.1|WP_047724173.1|4430760_4430985_-|hypothetical-protein
MSKIQYPMSTAAVFDDVVYPIHLNGPYQIESEVMGAIKWFCRWNNEEMAVVKAHVLFSCWGLYLTYDQLMAEAA
>NZ_CP011636.1|WP_004194002.1|4437967_4438114_-|hypothetical-protein
MPKSNRFYQAQTHKNVTRDRFVRSVNPVVAEKMRAILEELKRKEEGRE
>NZ_CP011636.1|WP_047684216.1|4438200_4438422_-|bacteriophage-CII-family-protein
MESSTTRNKVEARRIESWLHSQIAELGTTNIAKVAGVNKSTVSRWRESLLPNMSLLLAILISNRTGEKGGFEA
>NZ_CP011636.1|WP_047684213.1|4438462_4438696_-|helix-turn-helix-domain-containing-protein
MKNPAVEKAISIAGSQKELAKRCGKAQSTICDWLNGKKRISPVHVPDLVAAVNGEIKAHEFRPDLPSIFPPPNNSAA
>NZ_CP011636.1|WP_047684208.1|4438823_4439513_+|helix-turn-helix-transcriptional-regulator
MDFSERLARAMSLAGYTQGRLAKAVGMAQSSVNKLLNGANGSRKTVEIASVLGVRPEWLSTGAGEMLADSIQITQVQTPVTPQNGIYRVDVLDVKASAGPGALITNDFIETIRAIEYTSEQARSLFGNRPAHHIKVITVTGDSMDTTISPGDEIFVDISVTHFDSDGVYVFVFGKTLHVKRLQMQRDRLAVISDNPIYEKWYVEPGDEDQFYVMARVLLRQSIEYKRFA
>NZ_CP011636.1|WP_047724180.1|4439759_4440389_+|hypothetical-protein
MTSVRLTNALREQIAKNALAKSGVITAIESLDLKRQEVARDARIAAFGGKEQADKVDKQYEKLEKLEAELRSAGASLHISGNPQSSINIAISGRRLGWCSYGRTSEGKEIFLVTPNRDLCLFGAEHEITKRFDSLIDEEQKLNARKKEIEATVWAALKSVTTLSRLVEVWPESKELIPENVDSAKVALPALKVEDLNRLIGLPTESVEG
>NZ_CP011636.1|WP_162487899.1|4440508_4440634_+|hypothetical-protein
MLGWQMSKQGIRSLIYCLLICGVIWTALIIKILHATGVFNG
>NZ_CP011636.1|WP_019704100.1|4440626_4440821_+|hypothetical-protein
MANSIPNSGRAVMMRNAKTGATWKVSRDYLKETFWFEPQGNLRHIRKAFEARDLLPNLVPAGTH
>NZ_CP011636.1|WP_071846130.1|4441409_4441805_+|hypothetical-protein
MQPLPRLTADRLAVLPAGTRLKMGGHIVKLVGRGVFTNDAGITQNMVDYVDSRGVPGSFEEKIFLSTATEHLNAVMCEHCYALRHPNDCVVRNITNYMTSRQAHFCDDKGCAEKYFIKHPGRQKSGRRTKW
>NZ_CP011636.1|WP_162934436.1|4441798_4441942_+|hypothetical-protein
MVSQNAMLALAMVILAYDLQPVDLESAANQLAEFDAVNDAHTETKEC
>NZ_CP011636.1|WP_047724182.1|4441935_4442595_+|exodeoxyribonuclease-X
MLRVIDTETTSLEGSVLEIASVDIVDGVICNPMSDFVKPTEAISFEAMAIHHITEDMVADAPMISEVIGRYLGADAYVAHNAKFDKSKLPQIDAPWICTLKLARIQYPEFESHGNQYMRYRLGLKPELPEGLYAHRALYDCYVTAELLLYMGRLAKWTMGEMRTISNSPSLMKAIRFGKHKGLSFEEIAKVDPGYLRWLSSNSDDEDILFTIKHWLKGA

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Crispr_ID: NZ_CP011636_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011636_5

5834773-5834911

Orphan

Consensus_repeat	Method
TCTGCGCGGTATGGTAGCCCGGACAAGGCGCGTCAAGCGCCGCCTCCGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011636_5

>merge|NZ_CP011636|5|5834773-5834911|CRISPRCasFinder
TCTGCGCGGTATGGTAGCCCGGACAAGGCGCGTCAAGCGCCGCCTCCGGGGAAATCCCCGGCCGCGCTCACGCTTACCGGGGCTACAGTTCTGCGCGGTCTGGTAGCCCGGACAAGGCGCGTCAAGCGCCGCCTCCGGG

>NZ_CP011636|5|5|5834773-5834911|CRISPRCasFinder
TCTGCGCGGTATGGTAGCCCGGACAAGGCGCGTCAAGCGCCGCCTCCGGG	GAAATCCCCGGCCGCGCTCACGCTTACCGGGGCTACAGT
TCTGCGCGGTCTGGTAGCCCGGACAAGGCGCGTCAAGCGCCGCCTCCGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011636.1\|WP_032693019.1\|5832918_5833986_-\|HlyD-family-secretion-protein	unknown	unknown	gnl\|CDD\|224482
NZ_CP011636.1\|WP_014837323.1\|5827289_5828057_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|129344
NZ_CP011636.1\|WP_004098259.1\|5835026_5835191_-\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|227744
NZ_CP011636.1\|WP_004128539.1\|5829491_5829959_-\|membrane-protein	unknown	unknown	gnl\|CDD\|182513
NZ_CP011636.1\|WP_047724618.1\|5845985_5846429_-\|FosA-family-fosfomycin-resistance-glutathione-transferase	unknown	unknown	gnl\|CDD\|319908
NZ_CP011636.1\|WP_014227770.1\|5828053_5828308_+\|DUF3343-domain-containing-protein	unknown	unknown	gnl\|CDD\|378728
NZ_CP011636.1\|WP_014227768.1\|5829951_5830635_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225851
NZ_CP011636.1\|WP_047724615.1\|5841990_5842326_+\|endoribonuclease-SymE	unknown	unknown	gnl\|CDD\|237442
NZ_CP011636.1\|WP_047724613.1\|5838503_5841767_+\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NZ_CP011636.1\|WP_047724607.1\|5828367_5829471_-\|M20-peptidase-aminoacylase-family-protein	unknown	unknown	gnl\|CDD\|349939
NZ_CP011636.1\|WP_046878034.1\|5845438_5845726_-\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|225481
NZ_CP011636.1\|WP_025108161.1\|5830947_5831862_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176117
NZ_CP011636.1\|WP_004128506.1\|5843685_5845029_+\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP011636.1\|WP_000019450.1\|5837127_5838108_+\|IS5-like-element-ISKpn26-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP011636.1\|WP_014227757.1\|5845149_5845452_-\|BrnA-antitoxin-family-protein	unknown	unknown	gnl\|CDD\|226045
NZ_CP011636.1\|WP_047724616.1\|5842777_5843689_+\|acetamidase/formamidase-family-protein	unknown	unknown	gnl\|CDD\|225279
NZ_CP011636.1\|WP_014227766.1\|5833992_5834457_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|179596
NZ_CP011636.1\|WP_004128535.1\|5831864_5832929_-\|DUF2955-domain-containing-protein	unknown	unknown	gnl\|CDD\|371403
NZ_CP011636.1\|WP_047724610.1\|5835368_5836793_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP011636.1\|WP_025108164.1\|5826129_5827281_+\|2-hydroxyacyl-CoA-dehydratase-subunit-D	unknown	unknown	gnl\|CDD\|224689

Protein	Function_ID	Function_description	E-value
NZ_CP011636.1\|WP_032693019.1\|5832918_5833986_-\|HlyD-family-secretion-protein	gnl\|CDD\|224482	COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms].	4.02155e-62
NZ_CP011636.1\|WP_014837323.1\|5827289_5828057_+\|hypothetical-protein	gnl\|CDD\|129344	TIGR00241, Uncharacterized_protein_MJ0004, CoA-substrate-specific enzyme activase, putative. This domain is found in a set of closely related proteins including the (R)-2-hydroxyglutaryl-CoA dehydratase activase of Acidaminococcus fermentans, in longer proteins from M. jannaschii and M. thermoautotrophicum that share an additional N-terminal domain, in a protein described as a subunit of the benzoyl-CoA reductase of Rhodopseudomonas palustris, and in two repeats of an uncharacterized protein of Aquifex aeolicus.This domain may be involved in generating or regenerating the active sites of enzymes related to (R)-2-hydroxyglutaryl-CoA dehydratase and benzoyl-CoA reductase.	8.6828e-115
NZ_CP011636.1\|WP_004098259.1\|5835026_5835191_-\|DUF1127-domain-containing-protein	gnl\|CDD\|227744	COG5457, COG5457, Uncharacterized conserved small protein [Function unknown].	2.30042e-10
NZ_CP011636.1\|WP_004128539.1\|5829491_5829959_-\|membrane-protein	gnl\|CDD\|182513	PRK10519, PRK10519, hypothetical protein; Provisional.	9.84896e-72
NZ_CP011636.1\|WP_047724618.1\|5845985_5846429_-\|FosA-family-fosfomycin-resistance-glutathione-transferase	gnl\|CDD\|319908	cd07244, FosA, fosfomycin resistant protein subfamily FosA. This subfamily family contains FosA, a fosfomycin resistant protein. FosA is a Mn(II) and K(+)-dependent glutathione transferase. Fosfomycin inhibits the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase (MurA), which catalyzes the first committed step in bacterial cell wall biosynthesis. FosA, catalyzes the addition of glutathione to the antibiotic fosfomycin, (1R,2S)-epoxypropylphosphonic acid, making it inactive. FosA is a Mn(II) dependent enzyme. It is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.	1.08825e-67
NZ_CP011636.1\|WP_014227770.1\|5828053_5828308_+\|DUF3343-domain-containing-protein	gnl\|CDD\|378728	pfam11823, DUF3343, Protein of unknown function (DUF3343). This family of proteins are functionally uncharacterized. This protein is found in bacteria and archaea. Proteins in this family are typically between 78 to 102 amino acids in length.	1.59643e-14
NZ_CP011636.1\|WP_014227768.1\|5829951_5830635_-\|hypothetical-protein	gnl\|CDD\|225851	COG3314, COG3314, Uncharacterized protein conserved in bacteria [Function unknown].	4.59501e-18
NZ_CP011636.1\|WP_047724615.1\|5841990_5842326_+\|endoribonuclease-SymE	gnl\|CDD\|237442	PRK13605, PRK13605, endoribonuclease SymE; Provisional.	1.65904e-55
NZ_CP011636.1\|WP_047724613.1\|5838503_5841767_+\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	6.84589e-125
NZ_CP011636.1\|WP_047724607.1\|5828367_5829471_-\|M20-peptidase-aminoacylase-family-protein	gnl\|CDD\|349939	cd08018, M20_Acy1_amhX-like, M20 Peptidase aminoacylase 1 amhX-like subfamily. Peptidase M20 family, uncharacterized subfamily of proteins predicted as putative amidohydrolases, including the amhX gene product from Bacillus subtilis. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	0
NZ_CP011636.1\|WP_046878034.1\|5845438_5845726_-\|BrnT-family-toxin	gnl\|CDD\|225481	COG2929, COG2929, Uncharacterized protein conserved in bacteria [Function unknown].	3.31604e-35
NZ_CP011636.1\|WP_025108161.1\|5830947_5831862_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176117	cd08426, PBP2_LTTR_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.42353e-82
NZ_CP011636.1\|WP_004128506.1\|5843685_5845029_+\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	7.0878e-38
NZ_CP011636.1\|WP_000019450.1\|5837127_5838108_+\|IS5-like-element-ISKpn26-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	7.00081e-54
NZ_CP011636.1\|WP_014227757.1\|5845149_5845452_-\|BrnA-antitoxin-family-protein	gnl\|CDD\|226045	COG3514, COG3514, Uncharacterized protein conserved in bacteria [Function unknown].	1.24756e-20
NZ_CP011636.1\|WP_047724616.1\|5842777_5843689_+\|acetamidase/formamidase-family-protein	gnl\|CDD\|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	3.01463e-98
NZ_CP011636.1\|WP_014227766.1\|5833992_5834457_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|179596	PRK03573, PRK03573, transcriptional regulator SlyA; Provisional.	1.0958e-23
NZ_CP011636.1\|WP_004128535.1\|5831864_5832929_-\|DUF2955-domain-containing-protein	gnl\|CDD\|371403	pfam11168, DUF2955, Protein of unknown function (DUF2955). Some members in this family of proteins with unknown function annotate the proteins as membrane protein. However, this cannot be confirmed.	4.13788e-34
NZ_CP011636.1\|WP_047724610.1\|5835368_5836793_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	6.8273e-148
NZ_CP011636.1\|WP_025108164.1\|5826129_5827281_+\|2-hydroxyacyl-CoA-dehydratase-subunit-D	gnl\|CDD\|224689	COG1775, HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism].	4.90389e-151

>NZ_CP011636.1|WP_014227766.1|5833992_5834457_-|MarR-family-transcriptional-regulator
MTEDDLFARRPMGMRMAMVVRQWRAIIDSAITDTGLTQSSWTVLMQLHQLGDNVSVSELAEVQGIELPPLMRTLTQLEKQGYLLRSTSPYDKRIRLLTLTAEGRAILEKLNRVIETYQQRVTETIPEAQLAAFSATLNQIACNLRTIREEDNKI
>NZ_CP011636.1|WP_032693019.1|5832918_5833986_-|HlyD-family-secretion-protein
MMTPEQKFARWVRVSIAAFLAIFAWFIVADIWIPLTPDSTVMRVVTPVSSRVSGYVSHVYVHNNSQVKKGDLLYELDPTPFINKVEAAQIALEQAKLSNQQLDAQIASARANLRTAQYTARNDKVTFERYQRLSTMQNVSQSDLDKVRTTWQTSEQSVSALNASIQNLLIQRGERDDGRNVTLQKYRNALEEAQLNLGWTKVRAETDGMVSNLQLNPGLYATAATPLLALVSNQTDIVADFREKSLRHTGVNTDAAVVFDALPGKVFPAHVTSSDAGILAGQEEVNGQLSQPEQSTRWVRDAQRMRIHVALDEPLDKPLPTGARATVQLYNSDGPFARTFAGAQIHLVSFLHYVY
>NZ_CP011636.1|WP_004128535.1|5831864_5832929_-|DUF2955-domain-containing-protein
MSINTLARVFTPHGNIVYTANDFRQTLRIAVAGTIALSISTFYDVQYGVFFVVYPLMLLSLVPVFNRHVARQFVFSAAVNCVEMVLIVGYLSQWPVIMTLVVFGLYVMRFRFMSQGPLFLLGSMGVVCQSTMLNFMSYPTSNWHTLMFSNMEACVMAVALSALLNYFIPDVEPRKPPPRIEKDAARIRHESLLSGSVATMIFVIFQVCDLSDSLSALMAGILILFPMHYRGAVISSIWRVVGVVLACLYILVVQLIIYDFSNHMLLMMPLIGLGLAFSARLHVMEKVGAGVGFASITTIGIMFGQNLHPDQDLVFSDLYRITSVTVALIVTLTMVFLMHRLLNCFAPTRFVVTE
>NZ_CP011636.1|WP_025108161.1|5830947_5831862_+|LysR-family-transcriptional-regulator
MLHERPMSYLYEVGIQGGIRRAADMLGINPSVISRQIAQLERALELPLLERQGRNVVLTEAGRLLAEDYFESRQRREKLESHLKDLRHMRGGTISVRIGGGLVTTFIESVMSTFSQSWPNVFVDIIVGSMQEMLNDIASGEADMAVAFGPIGNPELKRHSFQWGPICAVVSPQHPIAALPAVTIDELTQYRLIALTDSFGLQRHMNAMFKTAGRQFHPAYRCNLFSTAMSLSQAGLGISFMTAYAAREAIAHGILTAVPIDHPIASSAQCHLLRNSDRRFSPAAHHMWRLLHNAFRDAQRALAA
>NZ_CP011636.1|WP_014227768.1|5829951_5830635_-|hypothetical-protein
MSENKTLECSSDETTNEWKVGPGAWISLIVVLLVFSGLLFKVEGMAWLGAFDFTTLGGAFGTMKTPETNTFIGSGGISAKAGFLFALSLVPTVMLALGLLEIFTHYGAIRAAHKLLTPLLRPLLGIPGYTGLALITDLQSTDAGAALTKELYDSDKINRKDLVIMGAWQYSGAGLINNYFSIGSALFASLTIPIIIPLLLMFVLKFVGAAITRLVLNTAYKRDFENE
>NZ_CP011636.1|WP_004128539.1|5829491_5829959_-|membrane-protein
MNNSAKVGSNPFDIFVIGARKGFNIAINNLMPNVLMAYVIAEMLNLLGVMQIIGHVCAPLMGLFGLPGEAITVLLTSWLSASAGTGVAVSLLSKGTLNVADITILIPAIFLMGSQLQYMGRLLGVADVPKKYWPLLMAVSIINAVIAMLVMRVIA
>NZ_CP011636.1|WP_047724607.1|5828367_5829471_-|M20-peptidase-aminoacylase-family-protein
MSRTLEHFNYLHQIPELGFEEHKTSAYIGDALEAAGFQVQRNVGGTTGIVALLDSGKPGPVVALRADMDALGHIIDGRLEARHTCGHDGHSSVVLTAAEEILAEGLVKRGKLKILFQPAEELGTGAIALTDAGALDDVEMLFGFHLRPLEECPKGKAVPAMYYSASATVMVDFHGKAAHAARPHLGVNALDAASHAVQAVNGIHLAPSLTWSAKATRFLCDAGVTNSVPAKAHVCWDLRSAENDGMATLKERVVRAIESSAAAYGATVDIQIVKEMPAAIIDEQATAIVSQAIRETFGEAGLTEAKSTPGSEDFFHYLRLRPQVKGGFWGLGCDLLPGLHHPEMHFDRAALADGVRVFKSCVRQLLG
>NZ_CP011636.1|WP_014227770.1|5828053_5828308_+|DUF3343-domain-containing-protein
MTEYLFLFHSTVGVVRMRKALQAAGASFRVKDIPRQLRGGCGLCIYLSCEPGEEQKWILPGQTEALFRVAGDDYQLLAQFPPQA
>NZ_CP011636.1|WP_014837323.1|5827289_5828057_+|hypothetical-protein
MTITVGIDSGSTATKGILLEDGVIQRRFLCPTPFRPADAIVEAWETLRAGLSERPFLTLTGYGRQLVDFADKQVTEISCHGLGARLLAPQTRTVIDIGGQDSKVIQLDEAGNLTDFLMNDKCAAGTGRFLEVISRTLGASVEQLDSITDGIEPHAITSMCTVFAESEVISLRSAGVPPEAILAGVINAMARRSANFIGRLSAQGPLLFTGGVSHCAAFARRLEGHVGMAVQTHPDAQFAGAIGAALIGLRQRSRR
>NZ_CP011636.1|WP_025108164.1|5826129_5827281_+|2-hydroxyacyl-CoA-dehydratase-subunit-D
MSLITDLPAIFDHFSAARQQGFLTVMELKEQNIPLVGTYCTFMPQEIPLAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLVVGETTCDGKKKMYEYMAEFKAVHVMQLPNSASDDASRALWKAEILRLQKVVEDRFGTPITEAALREAIILKNRERRALANFYRVGQLNPPALSGSDILKVVYGATFRFDKAALIDELNDMADRVRQQWQEGKRLEARPRILITGCPIGGAAEKVVKAIEDNGGWVVGFENCTGAKATERCVEETGDVYDALTDKYLAIGCSCISPNDQRLSLLSQMVDEYQADGVVDVILQACHTYAVESLAIKRHVRQQHDIPYIAIETDYSTADIGQLSTRVAAFIEML
>NZ_CP011636.1|WP_004098259.1|5835026_5835191_-|DUF1127-domain-containing-protein
MEFHENRARQPFIGFVFLARIIKKWWLREQTRRTLQRMSDEQLKDVGLRRDQIN
>NZ_CP011636.1|WP_047724610.1|5835368_5836793_+|PLP-dependent-aminotransferase-family-protein
MTRYQHLASLLAERIEQGLYRPGEKLPSLRSLSQEHGVSISTVQQAYQTLEQQQLIVPQPRSGYFVAPRKAQPPVPPMSRPVQRPVEITQWDQVLTMLDARHDKSIIPFGGGSPDVTQPSLKPIWRELSRAIQHNLSEVLNYDELAGRRELREQIARLMLDGGSVVTANDLVLTSGCHSALSLALLSVCQPGDIVAVESPCYYGTMQMLRGLGLKTIEIPTDPETGISIEALELALDQWPIKGVILVPNCNNPLGFIMPDARKRAALCLAQRHDIVIFEDDIYGELATEYPRPRTIHSWDIDGRVMLCSSFTKTIAPGLRIGWIAPGRYYDRLLQMKYAASGTNVPSTQLAACNFIREGHYHRHVRRMRQIYQRNMEIYTCWLREFFPCGICVTRPKGGFMLWVELPEQVDMVCVAKQLCRLKIQVAPGSLFSASGKYRNCLRINCALPPTDKHKEVMVQLGMAVKVAMEWEAQ
>NZ_CP011636.1|WP_000019450.1|5837127_5838108_+|IS5-like-element-ISKpn26-family-transposase
MSHQLTFADSEFSTKRRQTRKEIFLSRMEQILPWQNMTAVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGRVKTLKQHPRKNKTAINIEYMKASIRARVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRVDQMIRQWERSQ
>NZ_CP011636.1|WP_047724613.1|5838503_5841767_+|type-I-restriction-endonuclease-subunit-R
MPLSFSEAKLEQAIIELLQDQGYQHLIGDDVPRSSLDQVVIEDDLRHYFAARYQADGITDEEIQRLIKQFTTLPASDLYESNKTFCAWLANGFLFKRDDRQQKDLYIELLDTRHLPAALRELFDTEEVPLQQAAEPSASYLIQPLNRVKIVNQLTITGKENQPRIPDAILYINGLPLVVFEFKSAVREQEANIGDAYKQLCIRYRRDIPQLFVYNALCIISDGVNNRMGNLFAPYEYFYSWRKITGNENREQDGIPSLHSMIQGLFHPVRLLDVIKNFICFPDKAKHEVKICCRYPQYYAARKLYYSIERARKPFGDGKGGTYFGATGCGKSYTMQFLTRLLMKSVEFASPTIVLITDRTDLDDQLSAQMCNAKNYLGDDTVVPVTSRDDLREKLAGRNSGGVFLTTIHKFTEDTELLSGRSNIICISDEAHRSQVNLDQKVIVDKESGRVRKTYGFAKYLHDSLPQATYVGFTGTPIDATMEVFGNIVDSYTMTESVQDEITVRIVYEGRAAKVILDAGKLEEVEKYYDECANAGTNEWQIDESKKASATMNAILGDDDRLEALAEDFAKHYEKRVNEGSTVKGKAMFVCASREIAWDFYRQLKDFRPAWFEVKQAPDGIELTEQEAKELPPSEMVKMVMTRGKDDDAKLYDLLGSKEYRKELDKQFKNAKSNFKIAIVVDMWLTGFDVPELDTIYIDKPLQKHNLIQTISRVNRKLEGKSKGLVVDYIGIKRQMNQALAMYSRIDAANFEDIQQSVIEVKNHLDLLAQVLHDFDSRPYFSGEPQAQLACLNQAAEFVMRTQKTERRFMGLVKRLKAAYDVCCGSEALSQAERDRIHFYLAVRSIVFKLTKGDAPDVTQMNARVREMIADALKADGVEELFFLGDKKAESIDIFDEDYLARINKIKLPATKIQLLQKLLEKAISDFKKINQLQGINFTRRFQSIMDKYNERREDDVLNGEEFDSFSQEMTDIIYDIKTEMGTYAEMGIDIEEKAFYDILAHMRDKYQFTYEDDKMLALAKEMKAVVDNTSKYPDWSKRDDIKAKLKVELILLLHKHKFPPVANDDVYMGVLAQAENFKQHHINTLY
>NZ_CP011636.1|WP_047724615.1|5841990_5842326_+|endoribonuclease-SymE
MTTPHSIAEFTDPEVSPENNRKGTVSYASRFEDRQRIPAIIMKGQWLEAAGFATGTKIDIKVMEGCIVITAKQPEPELVESLRQLHKLSARKQKQVQALIGAIAGQKRKLA
>NZ_CP011636.1|WP_047724616.1|5842777_5843689_+|acetamidase/formamidase-family-protein
MKITKDRVVYAMSRDNAPVATVSSGSEVLFETCDCFSDQITSADAVFNELDWQRINPATGPVYVEGAEPGDALKVTIKRITLTSNQAVMVTAPQLGVIGDELDAPKVTIVPIENDHAVLPGNVRVPLNPMVGVIGVAPAGEAISCGTPDSHGGNMDCKMITAGSTLWLPVNVPGALFGLGDLHAAMGDGEVSVCGLEIPGEVLVELTVVKNRRLPLPMLENSETLFTLASALTLDDAAALATRNMAHFIADNTSLTLAEAISILSIAGDLQICQVVDPLKTCRYALPKSVAKQLSLSIEGEQA
>NZ_CP011636.1|WP_004128506.1|5843685_5845029_+|APC-family-permease
MSVEQFGYKQELHRALTFRDLLVYGMIFMVPIAPFGVFGYVWDGAQGMVALAYLIGMVAMFFTAMSYWSMSRAFPVSGSVYAYAQRGIHPIVGFFAGWLILLDYILVPSLLYIVSAAALAPMLPGVPGWLWIVGFIAINSLINLRGITFTARANNTILIAEIVVLSVFVVLGLIALYSGAGAGHLTLDPLYNADKFSLPLVMGAVSIAVLSFLGFDGISTLSEETKGGVDTVGKASLGALMLVGSLFILQTWIAADLAQGMTFSSLDTAFYDTANLAGGGWLKYVTMWSTVISWGIANALVAQAAVSRILFAMARDKQLPQLLAKVHPRLKTPYVSTLFVALISLASGLWFYGDIDNLSRLVNFGALMGFLVLHIAVINHYIIRQKSRNLVVHLLFPVVGLCIIGFVIYEMDAQAKVLGLSWLAVGVVYYLLMRLVLKRNVELKLEG
>NZ_CP011636.1|WP_014227757.1|5845149_5845452_-|BrnA-antitoxin-family-protein
MNMVKHKRDNPDTLTAKRDDELKALANKTDDEIDYSDIPATDDAQWSDAVRGKFYRPLKTQASVRIDADIMEWLKRPGKGYQTRLNAILREAMIRDLNKK
>NZ_CP011636.1|WP_046878034.1|5845438_5845726_-|BrnT-family-toxin
MPMEFEWDANKAISNLRKHGIRFEEAVLVFDDPRHLSRQDRYENGEYRWQTIGLVHGIIVIMVAHSVRFESGTEVIRIISARKADSKERNRYEHG
>NZ_CP011636.1|WP_047724618.1|5845985_5846429_-|FosA-family-fosfomycin-resistance-glutathione-transferase
MLSGLNHLTLAVSQLAPSVAFYQQLPGMTLRARWDNGAYFSCGDLWLCLSLDPQRRVISPEESDYTHYAFSIAEADFALFAGRLNAAGVPVWKTNKSEGASHYFLDPDGHKLELHVGSLAQRLAACRAKPYKGMVFFGEDEQAAGNP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP011636_3	3.1\|3307675\|58\|NZ_CP011636\|CRISPRCasFinder	3307675-3307732	58	NZ_CP011636.1	4176569-4176626	2	0.966

1. spacer 3.1|3307675|58|NZ_CP011636|CRISPRCasFinder matches to position: 4176569-4176626, mismatch: 2, identity: 0.966

tggcttcttcccggcttgcgctgcgcttagccgggctaccgggccgcagattgctggt	CRISPR spacer
tggcttcttcccggcttgcgctgcgcttagccgggctaccgggccgcagatcgccggt	Protospacer
***************************************************.**.***

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011636_4	4.1\|4437517\|27\|NZ_CP011636\|CRISPRCasFinder	4437517-4437543	27	NZ_LR134256	Klebsiella aerogenes strain NCTC9644 plasmid 3, complete sequence	1565-1591	1	0.963
NZ_CP011636_4	4.1\|4437517\|27\|NZ_CP011636\|CRISPRCasFinder	4437517-4437543	27	MN013086	Klebsiella phage vB_Kpn_Chronis, complete genome	33543-33569	3	0.889
NZ_CP011636_4	4.1\|4437517\|27\|NZ_CP011636\|CRISPRCasFinder	4437517-4437543	27	NC_017077	Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC7, complete sequence	20760-20786	7	0.741

1. spacer 4.1|4437517|27|NZ_CP011636|CRISPRCasFinder matches to NZ_LR134256 (Klebsiella aerogenes strain NCTC9644 plasmid 3, complete sequence) position: , mismatch: 1, identity: 0.963

ctccacctccgcaggcattggtattac	CRISPR spacer
ctccacctccgcaggcattggtactac	Protospacer
***********************.***

2. spacer 4.1|4437517|27|NZ_CP011636|CRISPRCasFinder matches to MN013086 (Klebsiella phage vB_Kpn_Chronis, complete genome) position: , mismatch: 3, identity: 0.889

ctccacctccgcaggcattggtattac	CRISPR spacer
atccacctccgcaggcattggtacgac	Protospacer
 **********************. **

3. spacer 4.1|4437517|27|NZ_CP011636|CRISPRCasFinder matches to NC_017077 (Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC7, complete sequence) position: , mismatch: 7, identity: 0.741

ctccacctccgcaggcattggtattac	CRISPR spacer
tggcacctccgcaggcattggtgcggc	Protospacer
.  *******************.. .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

934815 : 985232

Organic_Lake_phycodnavirus(20.0%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014227023.1\|934815_935781_-\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_032751514.1\|936109_936850_-	carbonic anhydrase family protein	NA	NA	NA	NA
WP_014227021.1\|936986_937868_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_032751512.1\|937879_939331_-	sodium/pantothenate symporter	NA	NA	NA	NA
WP_004125848.1\|939320_939563_-	YhdT family protein	NA	NA	NA	NA
WP_004125846.1\|939673_941023_-	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_004125844.1\|941033_941507_-	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_014227019.1\|941900_942500_-	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_014227018.1\|942499_943501_-	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_032751507.1\|943578_944553_-	oxidoreductase	NA	NA	NA	NA
WP_032751505.1\|944772_946713_+	RNase E specificity factor CsrD	NA	NA	NA	NA
WP_002918653.1\|947018_948062_+	rod shape-determining protein MreB	F2Y0P3	Organic_Lake_phycodnavirus	6.7e-05	22.3
WP_004106252.1\|948132_949119_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004125830.1\|949118_949607_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_047722867.1\|949614_950196_+	septum formation inhibitor Maf	NA	NA	NA	NA
WP_004125826.1\|950198_951668_+	ribonuclease G	NA	NA	NA	NA
WP_009651883.1\|951747_955545_+	AsmA2 domain-containing protein YhdP	NA	NA	NA	NA
WP_004854666.1\|955633_957079_+\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_025108485.1\|957137_957884_+	L-fucose operon activator	NA	NA	NA	NA
WP_004854659.1\|957880_958810_-	HTH-type transcriptional activator AaeR	NA	NA	NA	NA
WP_002918640.1\|958941_959145_+	AaeX family protein	NA	NA	NA	NA
WP_032751502.1\|959152_960085_+	p-hydroxybenzoic acid efflux pump subunit AaeA	NA	NA	NA	NA
WP_014227012.1\|960090_962058_+	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
WP_004854654.1\|962197_962473_+	barstar family protein	NA	NA	NA	NA
WP_004106229.1\|962523_962790_-	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_004106226.1\|962892_963156_-	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_004106225.1\|963510_963981_-	transcriptional regulator ArgR	NA	NA	NA	NA
WP_032751499.1\|964394_965333_+	malate dehydrogenase	NA	NA	NA	NA
WP_032751944.1\|965494_965932_+\|transposase	IS200/IS605 family transposase	A0A0A8WIU6	Clostridium_phage	1.2e-13	31.2
WP_047722868.1\|966098_966743_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_014227009.1\|966714_967380_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_014839648.1\|967590_968859_+	SLC13/DASS family transporter	Q6A201	Oenococcus_phage	4.0e-60	33.5
WP_047722870.1\|968891_969791_+	L(+)-tartrate dehydratase subunit alpha	NA	NA	NA	NA
WP_014227006.1\|969790_970408_+	L(+)-tartrate dehydratase subunit beta	NA	NA	NA	NA
WP_071846058.1\|970754_971006_+	oxaloacetate decarboxylase subunit gamma	NA	NA	NA	NA
WP_047722872.1\|971021_972779_+	sodium-extruding oxaloacetate decarboxylase subunit alpha	NA	NA	NA	NA
WP_014839646.1\|972794_974096_+	oxalacetate decarboxylase subunit beta	NA	NA	NA	NA
WP_047722873.1\|974309_975011_+	membrane protein associated with oxaloacetate decarboxylase	NA	NA	NA	NA
WP_009651894.1\|975038_976100_-	outer membrane-stress sensor serine endopeptidase DegS	NA	NA	NA	NA
WP_014226999.1\|976186_977554_-\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	4.3e-20	24.2
WP_004854637.1\|977726_978125_-	DUF1043 family protein	NA	NA	NA	NA
WP_032751487.1\|978315_979449_+	cell division protein ZapE	NA	NA	NA	NA
WP_004106200.1\|979668_980097_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_000829815.1\|980112_980505_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_148675737.1\|980562_980847_+	hypothetical protein	NA	NA	NA	NA
WP_014226997.1\|980816_981455_+	stringent starvation protein A	NA	NA	NA	NA
WP_014226996.1\|981458_981947_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	4.9e-27	54.7
WP_000019450.1\|983051_984032_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_000019450.1\|984251_985232_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

1238517 : 1279208

Erysipelothrix_phage(36.36%)

transposase,integrase

attL 1258929:1258942|attR 1280056:1280069

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_171972742.1\|1238517_1238742_+\|transposase	transposase	U5P4I9	Shigella_phage	2.7e-12	55.2
WP_052958991.1\|1239116_1240673_-	hypothetical protein	A0A2K5B2C2	Erysipelothrix_phage	5.2e-62	30.9
WP_013815099.1\|1240864_1241833_+\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.1
WP_077258068.1\|1241874_1243284_-	DEAD/DEAH box helicase family protein	A0A2K5B2C2	Erysipelothrix_phage	1.1e-50	35.0
WP_047722917.1\|1243280_1243967_-	DUF4276 family protein	NA	NA	NA	NA
WP_047722918.1\|1243959_1245066_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	1.2e-17	24.8
WP_047722919.1\|1245075_1246971_-	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	1.2e-108	37.3
WP_047722920.1\|1247010_1247709_-	DUF4391 domain-containing protein	NA	NA	NA	NA
WP_047722921.1\|1247705_1250999_-	DEAD/DEAH box helicase family protein	A0A2K5B253	Erysipelothrix_phage	6.8e-237	42.6
WP_028016388.1\|1253780_1254749_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_032425611.1\|1256276_1257308_-\|transposase	IS630-like element ISEc33 family transposase	NA	NA	NA	NA
WP_047722922.1\|1257592_1260241_-	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
1258929:1258942	attL	NA	NA	NA	NA
WP_047722923.1\|1260230_1262138_-	hypothetical protein	NA	NA	NA	NA
WP_047722924.1\|1262134_1263523_-	hypothetical protein	NA	NA	NA	NA
WP_047663486.1\|1264552_1265095_+	hypothetical protein	NA	NA	NA	NA
WP_047663485.1\|1265091_1265364_+	hypothetical protein	NA	NA	NA	NA
WP_047663484.1\|1265407_1266466_+	hypothetical protein	NA	NA	NA	NA
WP_047722925.1\|1266845_1268438_-\|transposase	IS66-like element ISKox1 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.6e-175	61.6
WP_004189161.1\|1268468_1268819_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	5.2e-39	63.8
WP_004189163.1\|1268815_1269256_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	2.6e-19	60.3
WP_047663483.1\|1269794_1270988_+	ATP-binding protein	NA	NA	NA	NA
WP_047663482.1\|1270980_1273371_+	S8 family serine peptidase	NA	NA	NA	NA
WP_047722926.1\|1273370_1273592_+	hypothetical protein	NA	NA	NA	NA
WP_047663481.1\|1273595_1274354_+	hypothetical protein	NA	NA	NA	NA
WP_047663480.1\|1274971_1275859_-	hypothetical protein	NA	NA	NA	NA
WP_044346295.1\|1275933_1276713_-	hypothetical protein	NA	NA	NA	NA
WP_040216727.1\|1276947_1277109_-	hypothetical protein	NA	NA	NA	NA
WP_044346284.1\|1277939_1279208_-\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	9.4e-78	37.6
1280056:1280069	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1761209 : 1823615

Paramecium_bursaria_Chlorella_virus(12.5%)

transposase,integrase

attL 1775371:1775386|attR 1806337:1806352

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000019450.1\|1761209_1762190_-\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_032425611.1\|1762766_1763798_-\|transposase	IS630-like element ISEc33 family transposase	NA	NA	NA	NA
WP_047724922.1\|1763858_1764443_+	fimbrial protein	NA	NA	NA	NA
WP_032750940.1\|1764592_1765252_+	molecular chaperone	NA	NA	NA	NA
WP_047723046.1\|1765279_1767814_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_032750938.1\|1767832_1768927_+	fimbrial protein	NA	NA	NA	NA
WP_014226484.1\|1769062_1769857_+	CatB-related O-acetyltransferase	M1HKK6	Paramecium_bursaria_Chlorella_virus	3.5e-06	28.6
WP_004853415.1\|1769892_1770666_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_047723048.1\|1770705_1771626_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025107304.1\|1771771_1772548_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	4.2e-12	26.2
WP_014839275.1\|1772611_1773805_+	MFS transporter	NA	NA	NA	NA
WP_047723049.1\|1774210_1775605_+	cytochrome-c peroxidase	NA	NA	NA	NA
1775371:1775386	attL	NA	NA	NA	NA
WP_032751934.1\|1775612_1776254_+	cytochrome c biogenesis heme-transporting ATPase CcmA	A0A2H4PQG7	Staphylococcus_phage	5.3e-13	27.9
WP_086074038.1\|1776253_1776910_+	heme exporter protein CcmB	NA	NA	NA	NA
WP_032750933.1\|1777007_1777745_+	heme ABC transporter permease	NA	NA	NA	NA
WP_032750932.1\|1777741_1777945_+	heme exporter protein CcmD	NA	NA	NA	NA
WP_014839268.1\|1777941_1778421_+	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_032750931.1\|1778417_1780355_+	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_014226473.1\|1780351_1780909_+	thiol:disulfide interchange protein DsbE	NA	NA	NA	NA
WP_047723050.1\|1780905_1781964_+	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_032751932.1\|1781960_1782893_-	glyoxylate/hydroxypyruvate reductase A	NA	NA	NA	NA
WP_004853394.1\|1782898_1783627_-	class II aldolase/adducin family protein	NA	NA	NA	NA
WP_032750929.1\|1783627_1785148_-	amino acid ABC transporter permease/ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-32	39.3
WP_009652546.1\|1785172_1785976_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_009652534.1\|1785985_1787062_-	isopenicillin N synthase family oxygenase	NA	NA	NA	NA
WP_032750928.1\|1787074_1787923_-	TIM barrel protein	NA	NA	NA	NA
WP_014226466.1\|1787933_1788884_-	agmatinase	NA	NA	NA	NA
WP_004135102.1\|1789000_1789912_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_047723051.1\|1790207_1790612_+	hypothetical protein	NA	NA	NA	NA
WP_047723052.1\|1790608_1792468_+	cell envelope integrity/translocation protein TolA	NA	NA	NA	NA
WP_032750925.1\|1793517_1795092_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_032751930.1\|1795193_1795673_+	hypothetical protein	NA	NA	NA	NA
WP_047723053.1\|1796193_1796457_-	hypothetical protein	NA	NA	NA	NA
WP_142988957.1\|1796509_1797542_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_032680458.1\|1797685_1798612_-	hypothetical protein	NA	NA	NA	NA
WP_187116901.1\|1798608_1799811_-	AAA family ATPase	NA	NA	NA	NA
WP_000019450.1\|1799842_1800823_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_047724925.1\|1801000_1802041_+	hypothetical protein	NA	NA	NA	NA
WP_047723055.1\|1802169_1802772_+\|integrase	tyrosine-type recombinase/integrase	A0A1V0E036	Clostridioides_phage	1.3e-05	29.4
WP_047723056.1\|1802921_1803539_-	hypothetical protein	NA	NA	NA	NA
WP_047723057.1\|1803901_1805209_-	McrC family protein	NA	NA	NA	NA
WP_047723058.1\|1805205_1807119_-	AAA family ATPase	K4I1H4	Acidithiobacillus_phage	4.6e-36	41.7
1806337:1806352	attR	NA	NA	NA	NA
WP_047723059.1\|1807696_1809376_-	SgrR family transcriptional regulator	NA	NA	NA	NA
WP_047723060.1\|1809598_1811125_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_047723061.1\|1811121_1811964_+	cytoplasmic protein	NA	NA	NA	NA
WP_052959012.1\|1811963_1812527_+	6-phospho-3-hexuloisomerase	NA	NA	NA	NA
WP_047723062.1\|1812550_1813186_+	3-hexulose-6-phosphate synthase	NA	NA	NA	NA
WP_047723063.1\|1813366_1814167_+	hypothetical protein	NA	NA	NA	NA
WP_047723064.1\|1814445_1815078_-	hypothetical protein	NA	NA	NA	NA
WP_047723065.1\|1815437_1816460_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_047723066.1\|1816470_1817451_-	PTS glucitol/sorbitol transporter subunit IIB	NA	NA	NA	NA
WP_047723067.1\|1817447_1817822_-	PTS glucitol/sorbitol transporter subunit IIA	NA	NA	NA	NA
WP_047723068.1\|1817818_1818340_-	PTS glucitol/sorbitol transporter subunit IIC	NA	NA	NA	NA
WP_047723069.1\|1818711_1819122_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148675610.1\|1819172_1819445_-	hypothetical protein	NA	NA	NA	NA
WP_047723070.1\|1819898_1821968_-	DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	3.5e-74	35.3
WP_047723071.1\|1822003_1822219_-	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_013815099.1\|1822646_1823615_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.1

DBSCAN-SWA_4

1827618 : 1874517

Enterobacterial_phage(28.21%)

tail,protease,holin,terminase,integrase,transposase,portal

attL 1824922:1824937|attR 1860752:1860767

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1824922:1824937	attL	NA	NA	NA	NA
WP_047723075.1\|1827618_1828866_-\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	3.2e-139	62.0
WP_071846078.1\|1829192_1829816_+	DUF4433 domain-containing protein	NA	NA	NA	NA
WP_047723077.1\|1829819_1830509_+	hypothetical protein	NA	NA	NA	NA
WP_000427623.1\|1831502_1832507_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_047723078.1\|1833249_1833816_-	3'-5' exoribonuclease	K7PLW7	Enterobacteria_phage	7.6e-80	72.6
WP_047723079.1\|1833817_1834015_-	hypothetical protein	NA	NA	NA	NA
WP_047723080.1\|1834014_1834542_-	hypothetical protein	A0A192Y8M4	Salmonella_phage	9.3e-64	69.1
WP_004123001.1\|1835557_1835929_-	hypothetical protein	Q8HAA1	Salmonella_phage	2.8e-59	93.5
WP_047723083.1\|1836594_1836816_-	hypothetical protein	NA	NA	NA	NA
WP_047723084.1\|1837019_1837646_-	LexA family transcriptional regulator	H9C160	Pectobacterium_phage	2.2e-43	45.1
WP_047723085.1\|1837746_1837956_+	cell division protein	NA	NA	NA	NA
WP_047723086.1\|1837983_1838541_+	hypothetical protein	A0A1C9II13	Salmonella_phage	6.6e-76	77.1
WP_052958994.1\|1838715_1839435_+	phage regulatory protein/antirepressor Ant	A0A2I7RHG4	Vibrio_phage	2.4e-46	50.9
WP_047723087.1\|1839436_1839616_+	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_047723088.1\|1839612_1840494_+	conserved phage C-terminal domain-containing protein	K7PLZ7	Enterobacterial_phage	6.2e-36	57.7
WP_047723089.1\|1840490_1840694_+	hypothetical protein	Q8W639	Enterobacteria_phage	1.2e-14	75.9
WP_047723090.1\|1840690_1841752_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	2.2e-104	53.1
WP_047723091.1\|1841768_1842131_+	antitermination protein Q	U5P0A5	Shigella_phage	1.7e-45	72.5
WP_047723092.1\|1842151_1842664_-	hypothetical protein	U5P455	Shigella_phage	3.7e-33	68.3
WP_047723093.1\|1842678_1843767_-	hypothetical protein	U5P4L0	Shigella_phage	1.2e-158	82.8
WP_012542177.1\|1844862_1845039_+	type II toxin-antitoxin system HicA family toxin	A0A0R6PD93	Moraxella_phage	1.4e-08	56.4
WP_047723094.1\|1845086_1845494_+	type II toxin-antitoxin system HicB family antitoxin	F1C593	Cronobacter_phage	4.4e-53	81.1
WP_032706073.1\|1845598_1845847_+\|holin	class II holin family protein	A0A127KNH9	Pseudomonas_phage	4.9e-07	35.1
WP_047723095.1\|1845848_1846382_+	lysozyme	G9L6J6	Escherichia_phage	6.3e-84	82.8
WP_047723096.1\|1846378_1846891_+	DUF2514 domain-containing protein	NA	NA	NA	NA
WP_047723097.1\|1846971_1847304_+	hypothetical protein	NA	NA	NA	NA
WP_047723098.1\|1847303_1847723_+	hypothetical protein	Q6UAS0	Klebsiella_phage	8.5e-36	54.3
WP_171972765.1\|1847743_1847992_+	hypothetical protein	NA	NA	NA	NA
WP_004111758.1\|1847954_1848443_+	DUF1441 family protein	K7PJY2	Enterobacterial_phage	2.5e-71	85.8
WP_004111760.1\|1848442_1850545_+\|terminase	phage terminase large subunit family protein	K7PH52	Enterobacterial_phage	0.0e+00	84.6
WP_004111762.1\|1850541_1850754_+	hypothetical protein	A5LH28	Enterobacteria_phage	1.9e-23	79.7
WP_032448882.1\|1850753_1852256_+\|portal	phage portal protein	K7PHM5	Enterobacterial_phage	9.6e-247	83.6
WP_071846079.1\|1852206_1854228_+\|protease	Clp protease ClpP	K7PKX4	Enterobacterial_phage	0.0e+00	82.7
WP_004122973.1\|1854309_1854636_+	DUF2190 family protein	K7PJY3	Enterobacterial_phage	1.6e-34	65.7
WP_047723100.1\|1854628_1854904_+	DNA breaking-rejoining protein	K7PH55	Enterobacterial_phage	4.9e-24	68.8
WP_047724949.1\|1854907_1855486_+\|tail	phage tail protein	K7PMB7	Enterobacterial_phage	5.6e-78	80.2
WP_047723101.1\|1855482_1855884_+\|tail	Minor tail protein U	K7PHM6	Enterobacterial_phage	2.7e-55	75.6
WP_047723102.1\|1855892_1856636_+\|tail	phage tail protein	K7PKX6	Enterobacterial_phage	1.4e-113	84.2
WP_020315038.1\|1856646_1857075_+\|tail	phage minor tail protein G	M9NZD7	Enterobacteria_phage	1.7e-36	60.7
WP_071846080.1\|1857095_1857410_+\|tail	phage tail assembly protein T	E4WL32	Enterobacteria_phage	1.2e-42	77.9
WP_047723103.1\|1857393_1860540_+\|tail	phage tail tape measure protein	E4WL33	Enterobacteria_phage	0.0e+00	71.8
WP_047723104.1\|1860546_1860894_+\|tail	phage tail protein	K7PJT2	Enterobacteria_phage	1.2e-35	62.6
1860752:1860767	attR	NA	NA	NA	NA
WP_047723105.1\|1860890_1861646_+\|tail	phage minor tail protein L	Q6UAW5	Klebsiella_phage	4.3e-131	84.9
WP_047723106.1\|1861647_1862358_+	C40 family peptidase	Q6UAW4	Klebsiella_phage	6.9e-139	92.4
WP_052958996.1\|1862370_1862805_+	hypothetical protein	K7PLY8	Enterobacterial_phage	2.5e-54	72.0
WP_004122963.1\|1862862_1863471_+\|tail	tail assembly protein	Q6UAW2	Klebsiella_phage	4.1e-79	75.7
WP_047723108.1\|1863535_1872835_+	DUF1983 domain-containing protein	Q6UAW1	Klebsiella_phage	0.0e+00	41.7
WP_047723109.1\|1872873_1874016_+\|tail	tail fiber domain-containing protein	A0A0D4D9I5	Escherichia_phage	9.8e-18	33.3
WP_004122957.1\|1874133_1874517_+	hypothetical protein	Q6UAV9	Klebsiella_phage	5.2e-64	90.6

DBSCAN-SWA_5

1993182 : 2008013

Morganella_phage(40.0%)

integrase

attL 1992945:1992965|attR 2011070:2011090

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1992945:1992965	attL	NA	NA	NA	NA
WP_047723114.1\|1993182_1994451_+\|integrase	site-specific integrase	A0A1W6JPG6	Morganella_phage	2.1e-146	60.8
WP_047723115.1\|1994458_1995412_+	hypothetical protein	NA	NA	NA	NA
WP_047723116.1\|1995538_1995757_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_047723117.1\|1995756_1996188_+	hypothetical protein	A0A1W6JPH9	Morganella_phage	2.4e-25	48.9
WP_047723118.1\|1996201_1997011_+	antA/AntB antirepressor family protein	A0A0R6PJV6	Moraxella_phage	3.5e-30	54.5
WP_004866306.1\|1997042_1997615_+	hypothetical protein	A0A1W6JPH8	Morganella_phage	8.0e-53	59.0
WP_004866303.1\|1997614_1997794_+	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_047723119.1\|1997790_1998753_+	ash family protein	A0A1C9IHV9	Salmonella_phage	2.4e-17	54.4
WP_047723120.1\|1998749_1999253_+	hypothetical protein	NA	NA	NA	NA
WP_047723121.1\|1999249_1999459_+	hypothetical protein	NA	NA	NA	NA
WP_047723122.1\|1999455_2000082_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	1.4e-26	38.3
WP_047723123.1\|2000091_2000442_+	hypothetical protein	A0A1B5FPL8	Escherichia_phage	2.4e-39	70.0
WP_047723124.1\|2000434_2003197_+	TOPRIM and DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	1.4e-291	55.9
WP_047723125.1\|2003314_2003533_+	hypothetical protein	NA	NA	NA	NA
WP_040216506.1\|2003535_2003982_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_047723126.1\|2003962_2004268_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_100117515.1\|2004337_2004661_+	superinfection immunity protein	A0A0S2SY85	Pseudomonas_phage	8.0e-18	45.0
WP_004866267.1\|2004797_2004968_+	hypothetical protein	NA	NA	NA	NA
WP_004848460.1\|2004967_2005294_+	hypothetical protein	NA	NA	NA	NA
WP_047723127.1\|2005301_2008013_+	tape measure protein	A0A1B1W284	Salmonella_phage	3.2e-51	31.6
2011070:2011090	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2383349 : 2391744

Planktothrix_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032719918.1\|2383349_2384213_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-11	29.0
WP_014230105.1\|2384223_2384997_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.8e-27	37.7
WP_032719859.1\|2385413_2386214_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014230103.1\|2386200_2386671_+	hypothetical protein	NA	NA	NA	NA
WP_047723272.1\|2386671_2387565_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	3.9e-14	29.3
WP_025107782.1\|2387809_2389171_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.6e-200	92.0
WP_014230101.1\|2389489_2390212_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	2.4e-30	32.7
WP_016946933.1\|2390208_2391744_-	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	2.8e-28	27.6

DBSCAN-SWA_7

2449877 : 2458448

Enterobacteria_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004122486.1\|2449877_2451284_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	5.6e-39	28.9
WP_047723320.1\|2451496_2452561_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.4e-103	54.7
WP_004122480.1\|2452574_2453444_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	3.7e-110	67.7
WP_014230058.1\|2453475_2454366_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.4e-27	32.1
WP_047723323.1\|2454381_2454936_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	1.2e-50	56.7
WP_032693859.1\|2455109_2456276_+	UDP-glucose 6-dehydrogenase	M1I798	Paramecium_bursaria_Chlorella_virus	7.0e-112	54.0
WP_004138729.1\|2456849_2456972_-	small membrane protein	NA	NA	NA	NA
WP_047723325.1\|2457443_2458448_-	NAD-dependent epimerase	E3T4Y8	Cafeteria_roenbergensis_virus	1.8e-31	29.2

DBSCAN-SWA_8

2533890 : 2637668

102

uncultured_Caudovirales_phage(23.4%)

tail,head,holin,terminase,integrase,transposase

attL 2601581:2601640|attR 2637923:2638046

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000019450.1\|2533890_2534871_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_047723401.1\|2535791_2536133_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_047724994.1\|2536423_2540026_-	hypothetical protein	NA	NA	NA	NA
WP_046878091.1\|2540722_2541640_+	nitrogen assimilation transcriptional regulator NAC	NA	NA	NA	NA
WP_014229985.1\|2541746_2542697_+	HTH-type transcriptional regulator Cbl	NA	NA	NA	NA
WP_047723403.1\|2542775_2543717_+	L,D-transpeptidase	NA	NA	NA	NA
WP_057174013.1\|2543838_2544447_-	glutathione S-transferase	NA	NA	NA	NA
WP_047723407.1\|2544623_2545550_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_047723408.1\|2545587_2546586_-	aldo/keto reductase	NA	NA	NA	NA
WP_047723410.1\|2546686_2547601_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	1.5e-08	30.2
WP_047723412.1\|2548547_2550005_+	EmmdR/YeeO family multidrug/toxin efflux MATE transporter	NA	NA	NA	NA
WP_047723414.1\|2550968_2552423_-	AMP nucleosidase	NA	NA	NA	NA
WP_014229908.1\|2552555_2552813_-	histidine kinase	NA	NA	NA	NA
WP_171972763.1\|2552988_2554524_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_014229906.1\|2554515_2555448_-	hypothetical protein	NA	NA	NA	NA
WP_025106074.1\|2555674_2556250_+	lipid IV(A) palmitoyltransferase PagP	NA	NA	NA	NA
WP_160741211.1\|2556284_2557208_-	acyltransferase family protein	NA	NA	NA	NA
WP_047723418.1\|2557246_2560309_-	efflux RND transporter permease subunit	S5VL66	Leptospira_phage	1.5e-25	22.3
WP_047723420.1\|2560308_2561394_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_047723422.1\|2561927_2562359_+	universal stress protein	A0A1W6JNV4	Morganella_phage	3.8e-23	43.4
WP_047723424.1\|2562409_2565097_+	cation-transporting P-type ATPase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	2.4e-70	27.8
WP_047723425.1\|2565285_2566215_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_047723427.1\|2566288_2566696_-	cupin domain-containing protein	NA	NA	NA	NA
WP_047724997.1\|2566823_2567726_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_047723431.1\|2567785_2568706_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_047723433.1\|2568846_2569242_+	RidA family protein	NA	NA	NA	NA
WP_047723434.1\|2569284_2570244_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_162557678.1\|2570620_2571421_-	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_013815099.1\|2572152_2573121_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.1
WP_000654805.1\|2573748_2574717_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	7.7e-181	96.9
WP_047723436.1\|2575628_2576621_-	glycosyltransferase family 2 protein	A8CG95	Salmonella_phage	1.3e-50	39.5
WP_000019450.1\|2576774_2577755_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_047723438.1\|2577793_2578207_-	GtrA family protein	NA	NA	NA	NA
WP_032749742.1\|2578852_2580046_-\|transposase	IS4 family transposase	S5FM71	Shigella_phage	1.5e-141	63.7
WP_025106098.1\|2580173_2581244_-	porin	Q1MVN1	Enterobacteria_phage	4.0e-90	51.1
WP_004852229.1\|2581872_2582154_+	hypothetical protein	NA	NA	NA	NA
WP_047723439.1\|2582196_2582892_+	phosphohydrolase	S4W232	Pandoravirus	5.2e-06	26.5
WP_047723440.1\|2582948_2584382_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	4.6e-97	53.5
WP_047723441.1\|2584362_2584857_+	very short patch repair endonuclease	E5E3X5	Burkholderia_phage	1.4e-32	50.0
WP_047723443.1\|2584831_2585743_-	drug/metabolite exporter YedA	NA	NA	NA	NA
WP_004852222.1\|2585926_2586838_+	DUF808 domain-containing protein	NA	NA	NA	NA
WP_025106102.1\|2586913_2587093_+	DUF2158 domain-containing protein	NA	NA	NA	NA
WP_014838854.1\|2587200_2588868_+	cellulose biosynthesis regulator YedQ	A0A127AWB9	Bacillus_phage	9.3e-17	36.7
WP_014229881.1\|2589197_2589413_-	YodD family peroxide/acid resistance protein	NA	NA	NA	NA
WP_004136599.1\|2589545_2589734_+	protein DsrB	NA	NA	NA	NA
WP_025106103.1\|2589775_2590399_-	transcriptional regulator RcsA	NA	NA	NA	NA
WP_161505342.1\|2590855_2591272_+	lipoprotein	NA	NA	NA	NA
WP_047723448.1\|2591321_2592809_-	alpha-amylase	NA	NA	NA	NA
WP_014229877.1\|2593010_2593811_+	cystine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_025106106.1\|2593906_2594893_+	D-cysteine desulfhydrase	NA	NA	NA	NA
WP_004103458.1\|2594908_2595577_+	cystine ABC transporter permease	NA	NA	NA	NA
WP_004852203.1\|2595573_2596326_+	L-cystine ABC transporter ATP-binding protein YecC	G3M9Y6	Bacillus_virus	3.4e-27	34.9
WP_014229875.1\|2596627_2597350_+	transcriptional regulator SdiA	NA	NA	NA	NA
WP_004122104.1\|2597417_2597642_-	DUF2594 family protein	NA	NA	NA	NA
WP_004122102.1\|2598105_2598762_+	UvrY/SirA/GacA family response regulator transcription factor	NA	NA	NA	NA
WP_047723450.1\|2598758_2600591_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_004122100.1\|2600648_2601197_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
2601581:2601640	attL	NA	NA	NA	NA
WP_047723452.1\|2601766_2602783_-\|integrase	tyrosine-type recombinase/integrase	H9C152	Pectobacterium_phage	1.6e-125	64.5
WP_032409868.1\|2602766_2603012_-	DUF4224 domain-containing protein	H9C153	Pectobacterium_phage	2.8e-07	41.4
WP_015365915.1\|2603221_2603407_-	hypothetical protein	NA	NA	NA	NA
WP_047723454.1\|2603408_2603975_-	siphovirus Gp157 family protein	H9C156	Pectobacterium_phage	7.9e-53	62.5
WP_047723456.1\|2603971_2606125_-	hypothetical protein	H9C157	Pectobacterium_phage	1.3e-95	34.0
WP_029602739.1\|2606169_2606403_-	hypothetical protein	NA	NA	NA	NA
WP_047723458.1\|2607013_2607469_-	helix-turn-helix domain-containing protein	A0A0U2QW76	Escherichia_phage	4.1e-36	55.0
WP_000364674.1\|2607577_2607811_+	helix-turn-helix transcriptional regulator	A0A0U2S629	Escherichia_phage	2.9e-09	44.4
WP_015365920.1\|2607873_2608320_+	hypothetical protein	H9C162	Pectobacterium_phage	1.7e-26	51.4
WP_029602737.1\|2608403_2608562_+	hypothetical protein	NA	NA	NA	NA
WP_047723461.1\|2608564_2608936_+	HNH endonuclease	K4PAA9	Pseudomonas_phage	3.5e-17	40.0
WP_047723465.1\|2609962_2611351_+	AAA family ATPase	Q8HA30	Enterobacteria_phage	2.6e-105	46.6
WP_047723466.1\|2611389_2612058_+	hypothetical protein	NA	NA	NA	NA
WP_047723467.1\|2612061_2612295_+	hypothetical protein	NA	NA	NA	NA
WP_047723469.1\|2612458_2613049_+	adenine methylase	A0A2R9YJG0	Escherichia_phage	6.7e-95	85.7
WP_009308338.1\|2613051_2613282_+	hypothetical protein	A0A2H4JCC5	uncultured_Caudovirales_phage	2.9e-06	38.7
WP_047723471.1\|2613278_2613896_+	HNH endonuclease	A0A2H4JEM6	uncultured_Caudovirales_phage	8.8e-05	24.3
WP_071846091.1\|2613908_2614247_+	hypothetical protein	A0A193GYX4	Enterobacter_phage	3.5e-48	84.7
WP_041165550.1\|2614429_2614621_+	hypothetical protein	NA	NA	NA	NA
WP_047723476.1\|2614689_2615286_+	DUF1367 family protein	H9C173	Pectobacterium_phage	2.3e-79	70.7
WP_171972762.1\|2615296_2615773_+	HNH endonuclease	H2EI88	Brucella_phage	4.1e-18	41.6
WP_077258078.1\|2615690_2616068_+	hypothetical protein	A0A1I9KFA7	Aeromonas_phage	6.5e-19	47.4
WP_171972761.1\|2616055_2616220_+	hypothetical protein	NA	NA	NA	NA
WP_015365933.1\|2616223_2616520_+	hypothetical protein	NA	NA	NA	NA
WP_047723486.1\|2616547_2617000_+	hypothetical protein	NA	NA	NA	NA
WP_047723487.1\|2617010_2617232_+	hypothetical protein	NA	NA	NA	NA
WP_047723488.1\|2617235_2618861_+\|head,tail	head-tail connector protein	A0A2H4J3N6	uncultured_Caudovirales_phage	1.2e-173	59.5
WP_032409894.1\|2618857_2619091_+	hypothetical protein	NA	NA	NA	NA
WP_047723489.1\|2619077_2619926_+	hypothetical protein	A0A2H4JEQ5	uncultured_Caudovirales_phage	8.2e-46	42.9
WP_047723491.1\|2619959_2620427_+	DUF2829 domain-containing protein	A0A1B0VMG3	Pseudomonas_phage	4.5e-46	58.6
WP_047723493.1\|2620462_2620756_+	hypothetical protein	G8C7W3	Escherichia_phage	2.2e-30	69.1
WP_047723494.1\|2620970_2621882_+	hypothetical protein	A0A2H4JC66	uncultured_Caudovirales_phage	1.4e-43	38.6
WP_047723496.1\|2621941_2622505_+	hypothetical protein	A0A2H4JID6	uncultured_Caudovirales_phage	1.8e-49	51.9
WP_047723497.1\|2622506_2624501_+	hypothetical protein	A0A2H4J6H2	uncultured_Caudovirales_phage	1.7e-182	47.9
WP_047723499.1\|2624503_2624953_+	GNAT family N-acetyltransferase	A0A2H4J9Z5	uncultured_Caudovirales_phage	1.5e-22	43.0
WP_047723501.1\|2624955_2625444_+	hypothetical protein	A0A2H4J679	uncultured_Caudovirales_phage	6.7e-08	42.0
WP_047723503.1\|2625449_2628164_+	transglycosylase SLT domain-containing protein	G9L6D3	Escherichia_phage	3.1e-288	60.2
WP_047723505.1\|2628163_2631055_+	hypothetical protein	G9L6D4	Escherichia_phage	0.0e+00	71.5
WP_047723506.1\|2631058_2631493_-	hypothetical protein	NA	NA	NA	NA
WP_047723508.1\|2631632_2631974_+	hypothetical protein	A0A2H4J7H0	uncultured_Caudovirales_phage	4.8e-21	52.7
WP_047723509.1\|2631970_2633581_+\|terminase	phage terminase large subunit	A0A2H4JCA3	uncultured_Caudovirales_phage	1.1e-224	70.1
WP_171972773.1\|2633946_2636271_+	hypothetical protein	A0A2K9VAJ3	Klebsiella_virus	4.6e-46	33.2
WP_047723513.1\|2636567_2636792_+\|holin	class II holin family protein	A0A0P0ZFW5	Escherichia_phage	1.2e-20	70.1
WP_047723514.1\|2636775_2637312_+	lysozyme	H6WRZ4	Salmonella_phage	7.2e-80	77.3
WP_047723516.1\|2637308_2637668_+	hypothetical protein	R9TPM9	Aeromonas_phage	1.9e-15	42.2
2637923:2638046	attR	NA	NA	NA	NA

DBSCAN-SWA_9

2985446 : 3030070

Escherichia_phage(33.33%)

plate,transposase,integrase

attL 3008973:3008989|attR 3036234:3036250

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014838714.1\|2985446_2986787_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_032749821.1\|2986783_2987473_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_032749819.1\|2987469_2989182_+	OmpA family protein	NA	NA	NA	NA
WP_014839086.1\|2989186_2989678_+	type VI secretion system effector Hcp	NA	NA	NA	NA
WP_032749817.1\|2989966_2990332_+	hypothetical protein	NA	NA	NA	NA
WP_047723681.1\|2990328_2992680_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	9.7e-20	32.2
WP_032749811.1\|2992694_2994983_+	hypothetical protein	NA	NA	NA	NA
WP_032749810.1\|2994986_2995679_+	hypothetical protein	NA	NA	NA	NA
WP_185962836.1\|2995965_2996253_+	hypothetical protein	NA	NA	NA	NA
WP_032749809.1\|2996413_2996611_+	hypothetical protein	NA	NA	NA	NA
WP_047723683.1\|2996852_2997599_+	hypothetical protein	NA	NA	NA	NA
WP_032749807.1\|2997630_2998839_+	hypothetical protein	NA	NA	NA	NA
WP_047723685.1\|2998835_3002303_+	type VI secretion protein VasK	NA	NA	NA	NA
WP_071846096.1\|3002805_3003084_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_047723689.1\|3003183_3004938_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_047723691.1\|3004901_3005987_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_047723692.1\|3005964_3006510_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004851647.1\|3007010_3008099_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_025105882.1\|3008170_3009940_+	iron ABC transporter permease	NA	NA	NA	NA
3008973:3008989	attL	NA	NA	NA	NA
WP_047723695.1\|3009932_3011003_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-30	38.6
WP_047723697.1\|3011059_3011830_-	(S)-acetoin forming diacetyl reductase	NA	NA	NA	NA
WP_047723698.1\|3011853_3013533_-	acetolactate synthase AlsS	NA	NA	NA	NA
WP_004851637.1\|3013543_3014323_-	acetolactate decarboxylase	NA	NA	NA	NA
WP_014229640.1\|3014429_3015302_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.3e-05	27.3
WP_004136705.1\|3015330_3015543_-	cold shock-like protein CspF	NA	NA	NA	NA
WP_032749742.1\|3015725_3016919_+\|transposase	IS4 family transposase	S5FM71	Shigella_phage	1.5e-141	63.7
WP_047723700.1\|3017669_3018857_+	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_047723702.1\|3018849_3020268_+	sodium:proton antiporter	NA	NA	NA	NA
WP_004851627.1\|3020390_3020531_-	hypothetical protein	NA	NA	NA	NA
WP_025105876.1\|3020846_3021755_+	DUF535 family protein	NA	NA	NA	NA
WP_025105875.1\|3021870_3022542_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014838689.1\|3022946_3023498_+\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	2.6e-53	55.1
WP_025105874.1\|3023535_3024063_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_047723703.1\|3024108_3025110_-	fimbrial protein	NA	NA	NA	NA
WP_047723704.1\|3025125_3027696_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_025105871.1\|3027756_3028446_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_032749776.1\|3028546_3029065_-	fimbrial protein	NA	NA	NA	NA
WP_032749775.1\|3029521_3030070_-\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	7.2e-51	51.9
3036234:3036250	attR	NA	NA	NA	NA

DBSCAN-SWA_10

3362091 : 3393231

Enterobacteria_phage(30.77%)

tail,protease,holin,integrase,tRNA,transposase

attL 3365334:3365351|attR 3390173:3390190

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032425611.1\|3362091_3363123_-\|transposase	IS630-like element ISEc33 family transposase	NA	NA	NA	NA
WP_008324213.1\|3363282_3364143_+	WYL domain-containing protein	NA	NA	NA	NA
WP_008324215.1\|3364150_3364669_+	hypothetical protein	NA	NA	NA	NA
WP_000019450.1\|3365243_3366224_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
3365334:3365351	attL	NA	NA	NA	NA
WP_008325196.1\|3368101_3369109_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_170912124.1\|3370379_3371471_-	oxidoreductase	NA	NA	NA	NA
WP_032749353.1\|3371463_3372207_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	8.6e-15	27.2
WP_025107979.1\|3372823_3373444_+	response regulator transcription factor	NA	NA	NA	NA
WP_004850311.1\|3373786_3374770_+	zinc transporter ZntB	NA	NA	NA	NA
WP_032749350.1\|3375253_3376627_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.8e-50	31.8
WP_004850317.1\|3376671_3377607_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.4e-139	93.4
WP_032749348.1\|3377810_3378083_+	hypothetical protein	NA	NA	NA	NA
WP_025107976.1\|3378420_3379359_+\|protease	omptin family outer membrane protease	NA	NA	NA	NA
WP_014229121.1\|3379757_3380048_-	Bor family protein	C6ZCX3	Enterobacteria_phage	9.7e-31	66.0
WP_004101601.1\|3380236_3380671_-	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	7.2e-30	51.4
WP_004850325.1\|3380753_3380966_-	KTSC domain-containing protein	NA	NA	NA	NA
WP_009652979.1\|3381119_3382226_-	porin OmpC	Q1MVN1	Enterobacteria_phage	4.9e-107	57.4
WP_032750138.1\|3382583_3386111_-	pyruvate:ferredoxin (flavodoxin) oxidoreductase	NA	NA	NA	NA
WP_046877232.1\|3386591_3387293_+	helix-turn-helix transcriptional regulator	K7PKK1	Enterobacteria_phage	2.5e-32	40.0
WP_014229124.1\|3387756_3388119_+	hypothetical protein	C6ZR44	Salmonella_phage	7.1e-31	57.5
WP_009653048.1\|3388195_3388588_+\|holin	phage holin family protein	K7PHB9	Enterobacterial_phage	1.3e-38	66.2
WP_032749344.1\|3388577_3388850_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	2.2e-16	55.4
WP_004850338.1\|3388857_3389400_+	glycoside hydrolase family 108 protein	A0A0U2I1S0	Escherichia_phage	5.2e-70	66.7
WP_004850340.1\|3389455_3389875_+	hypothetical protein	Q6UAS0	Klebsiella_phage	9.4e-35	51.5
WP_000019450.1\|3390082_3391063_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
3390173:3390190	attR	NA	NA	NA	NA
WP_000019450.1\|3391282_3392263_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_047723803.1\|3392478_3393231_+\|tail	phage minor tail protein L	K7PKU0	Enterobacteria_phage	1.7e-114	75.9

DBSCAN-SWA_11

3781570 : 3866777

Salmonella_phage(19.05%)

capsid,tail,head,holin,terminase,integrase,plate,transposase,portal

attL 3820351:3820367|attR 3874762:3874778

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032425611.1\|3781570_3782602_+\|transposase	IS630-like element ISEc33 family transposase	NA	NA	NA	NA
WP_008324210.1\|3782702_3783884_+	hypothetical protein	NA	NA	NA	NA
WP_023063206.1\|3783880_3786109_+	Mov34/MPN/PAD-1 family protein	NA	NA	NA	NA
WP_004850301.1\|3786281_3786704_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.6e-32	51.2
WP_014229113.1\|3786991_3787186_+	hypothetical protein	NA	NA	NA	NA
WP_004850297.1\|3787342_3787534_+	hypothetical protein	NA	NA	NA	NA
WP_047723940.1\|3787711_3788026_+	PTS cellobiose transporter subunit IIB	NA	NA	NA	NA
WP_014229112.1\|3788080_3788644_-	DUF1440 domain-containing protein	NA	NA	NA	NA
WP_032720811.1\|3788840_3789422_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_014838304.1\|3789547_3790177_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_071532263.1\|3790538_3790727_-	cold-shock protein	NA	NA	NA	NA
WP_032749356.1\|3791442_3792423_-	nitronate monooxygenase	NA	NA	NA	NA
WP_004850284.1\|3792581_3793466_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_014838299.1\|3793579_3794464_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_014229103.1\|3794635_3795772_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_162934453.1\|3795915_3797103_+	MFS transporter	NA	NA	NA	NA
WP_071846167.1\|3797200_3797545_+	DUF1294 domain-containing protein	NA	NA	NA	NA
WP_032693666.1\|3797645_3798371_+	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	3.5e-45	46.4
WP_047723942.1\|3798612_3799047_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_038424404.1\|3799043_3799763_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_032749366.1\|3799759_3801019_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_047723943.1\|3801020_3801743_+	DUF1365 domain-containing protein	NA	NA	NA	NA
WP_047723944.1\|3801739_3802963_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_032749369.1\|3802959_3803493_+	DUF3833 domain-containing protein	NA	NA	NA	NA
WP_014229093.1\|3803507_3804467_+	DUF523 and DUF1722 domain-containing protein	NA	NA	NA	NA
WP_032749371.1\|3804530_3805913_-	carbohydrate porin	NA	NA	NA	NA
WP_187116904.1\|3806794_3806971_+	hypothetical protein	NA	NA	NA	NA
WP_013815099.1\|3806996_3807965_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.1
WP_000019450.1\|3810914_3811895_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_071846113.1\|3812042_3814415_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.0e-21	31.6
WP_047723945.1\|3814411_3817054_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	2.2e-97	32.6
WP_014229074.1\|3817300_3817792_-	type VI secretion system effector Hcp	NA	NA	NA	NA
WP_032749392.1\|3817936_3819625_-	OmpA family protein	NA	NA	NA	NA
WP_014229072.1\|3819621_3820287_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_047723946.1\|3820283_3821627_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
3820351:3820367	attL	NA	NA	NA	NA
WP_025108179.1\|3821640_3823176_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_014229069.1\|3823216_3823708_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_047723947.1\|3824406_3824613_+	hypothetical protein	NA	NA	NA	NA
WP_019705237.1\|3824746_3824995_+	DinI-like family protein	S5MQI1	Escherichia_phage	1.0e-25	70.4
WP_047723949.1\|3825901_3826450_-	recombinase family protein	A0A286S1P7	Klebsiella_phage	9.6e-88	92.3
WP_148675741.1\|3826570_3827032_+	hypothetical protein	NA	NA	NA	NA
WP_171972736.1\|3827063_3827240_-	hypothetical protein	NA	NA	NA	NA
WP_047723951.1\|3827247_3829677_-	hypothetical protein	A0A2K9VAJ3	Klebsiella_virus	3.8e-43	33.0
WP_047723952.1\|3829700_3830279_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	1.2e-48	51.6
WP_047723953.1\|3830278_3831034_-\|tail	tail fiber protein	E5G6P0	Salmonella_phage	1.0e-26	52.8
WP_047723954.1\|3831101_3831767_-	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_047723955.1\|3831763_3832912_-\|plate	baseplate J/gp47 family protein	R9TN81	Rhizobium_phage	6.8e-19	24.9
WP_047723956.1\|3832901_3833351_-	phage GP46 family protein	A0A0C4UR04	Shigella_phage	1.6e-19	45.1
WP_117254196.1\|3833347_3833887_-\|plate	phage baseplate assembly protein	A0A077KAY0	Edwardsiella_phage	2.5e-11	41.7
WP_047723958.1\|3833922_3835002_-\|tail	tail protein	Q8SBG7	Shigella_phage	1.8e-37	31.9
WP_047723959.1\|3834998_3836399_-	DNA circularization protein	NA	NA	NA	NA
WP_142988938.1\|3836467_3836857_-	hypothetical protein	NA	NA	NA	NA
WP_047723961.1\|3836929_3838699_-	transglycosylase SLT domain-containing protein	I6ZXX9	Escherichia_phage	1.2e-27	48.5
WP_047723962.1\|3838843_3839122_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_047723963.1\|3839125_3839494_-\|tail	phage tail tube protein	NA	NA	NA	NA
WP_047723964.1\|3839497_3841015_-\|tail	phage tail sheath subtilisin-like domain-containing protein	B5TK67	Pseudomonas_phage	1.4e-104	43.8
WP_047723965.1\|3841015_3841195_-	DUF2635 domain-containing protein	A0A2P9JZJ7	Alteromonadaceae_phage	7.8e-07	57.1
WP_047723966.1\|3841197_3841743_-	hypothetical protein	NA	NA	NA	NA
WP_047723967.1\|3841739_3842099_-	hypothetical protein	NA	NA	NA	NA
WP_042944986.1\|3842104_3842473_-	hypothetical protein	NA	NA	NA	NA
WP_047723968.1\|3842474_3843524_-\|capsid	major capsid protein	V5Q8G6	Xylella_phage	2.1e-51	33.7
WP_047723969.1\|3843621_3844026_-\|head	head decoration protein	NA	NA	NA	NA
WP_047723970.1\|3844025_3844604_-	hypothetical protein	NA	NA	NA	NA
WP_047723971.1\|3844605_3845475_-	S49 family peptidase	K4I1N3	Providencia_phage	5.5e-53	39.7
WP_047723972.1\|3845471_3847109_-\|portal	phage portal protein	A0A291AUL8	Sinorhizobium_phage	5.2e-89	35.8
WP_025713573.1\|3847108_3847369_-\|head,tail	phage head-tail adapter protein	NA	NA	NA	NA
WP_052959003.1\|3847377_3849501_-\|terminase	phage terminase large subunit family protein	A0A0C5ABH4	Bacteriophage	7.5e-96	34.2
WP_047723973.1\|3849442_3850006_-	hypothetical protein	NA	NA	NA	NA
WP_047723974.1\|3850326_3850599_+	hypothetical protein	NA	NA	NA	NA
WP_047723975.1\|3850724_3851363_-	hypothetical protein	NA	NA	NA	NA
WP_047723976.1\|3851414_3851699_-	hypothetical protein	Q8W634	Enterobacteria_phage	3.0e-24	62.2
WP_047723977.1\|3851924_3852314_-	hypothetical protein	A0A192Y6H8	Salmonella_phage	2.2e-22	50.0
WP_047723978.1\|3852463_3853018_+	hypothetical protein	NA	NA	NA	NA
WP_047723979.1\|3853077_3853575_-	lysozyme	A0A1V0E5Q7	Salmonella_phage	2.8e-78	82.4
WP_047723980.1\|3853552_3853822_-\|holin	holin	K7P6H9	Enterobacteria_phage	2.1e-35	81.5
WP_025714746.1\|3854183_3854966_-	antitermination protein	A0A286N2Q2	Klebsiella_phage	1.8e-132	88.8
WP_031592532.1\|3854962_3855331_-	RusA family crossover junction endodeoxyribonuclease	G8C7V6	Escherichia_phage	2.1e-38	60.3
WP_047723981.1\|3855317_3856697_-	AAA family ATPase	Q8W640	Enterobacteria_phage	9.6e-161	65.4
WP_047723982.1\|3856693_3857572_-	ATP-binding protein	Q8W641	Enterobacteria_phage	1.9e-85	63.9
WP_047723983.1\|3857583_3858513_-	helix-turn-helix domain-containing protein	Q8W642	Enterobacteria_phage	1.0e-113	74.1
WP_047723984.1\|3858606_3858900_-	hypothetical protein	NA	NA	NA	NA
WP_164880234.1\|3858896_3859349_-	hypothetical protein	NA	NA	NA	NA
WP_077258083.1\|3859350_3859587_-	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	9.7e-13	55.7
WP_047723986.1\|3859710_3860412_+	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	1.1e-56	52.0
WP_047723987.1\|3860592_3860784_+	hypothetical protein	NA	NA	NA	NA
WP_047723988.1\|3860780_3860969_+	hypothetical protein	NA	NA	NA	NA
WP_047723989.1\|3860965_3861193_+	hypothetical protein	A0A1B5FPB2	Escherichia_phage	9.0e-08	53.4
WP_071846116.1\|3861143_3861383_+	hypothetical protein	NA	NA	NA	NA
WP_047723990.1\|3861445_3861709_+	hypothetical protein	NA	NA	NA	NA
WP_047723991.1\|3861851_3862046_+	hypothetical protein	NA	NA	NA	NA
WP_047723992.1\|3862002_3862383_+	hypothetical protein	A0A1B5FPB3	Escherichia_phage	1.3e-22	50.9
WP_020803898.1\|3862431_3862596_+	hypothetical protein	A0A1B5FPB7	Escherichia_phage	7.2e-15	74.1
WP_020805575.1\|3862567_3862789_+	hypothetical protein	A0A286S1P6	Klebsiella_phage	1.5e-28	91.3
WP_047723993.1\|3862785_3863226_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	5.7e-67	87.4
WP_047723996.1\|3863269_3863788_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	4.1e-80	81.4
WP_171972734.1\|3863793_3864510_+	Rha family transcriptional regulator	A0A286S260	Klebsiella_phage	4.6e-122	94.9
WP_047719113.1\|3865066_3865288_+	hypothetical protein	A0A286S2B3	Klebsiella_phage	1.1e-26	84.9
WP_004198241.1\|3865423_3865615_+	hypothetical protein	A0A0M4RTZ2	Salmonella_phage	3.9e-20	73.8
WP_047719115.1\|3865595_3866777_-\|integrase	site-specific integrase	A0A0M4QX09	Salmonella_phage	1.8e-200	83.5
3874762:3874778	attR	NA	NA	NA	NA

DBSCAN-SWA_12

4022656 : 4088239

Enterobacteria_phage(59.38%)

capsid,tail,head,terminase,integrase,tRNA,plate,transposase,portal

attL 4024811:4024828|attR 4078509:4078526

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032749533.1\|4022656_4023157_+\|tRNA	YbaK/prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
WP_004138309.1\|4023320_4023767_+	DUF441 domain-containing protein	NA	NA	NA	NA
WP_162934470.1\|4023750_4024545_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_025106946.1\|4024642_4025827_+	CynX/NimT family MFS transporter	NA	NA	NA	NA
4024811:4024828	attL	NA	NA	NA	NA
WP_032749536.1\|4025864_4026557_-	CTP synthase	NA	NA	NA	NA
WP_032749537.1\|4026719_4027229_+	DUF523 domain-containing protein	NA	NA	NA	NA
WP_014228940.1\|4027215_4027560_+	DUF488 domain-containing protein	NA	NA	NA	NA
WP_025106943.1\|4027554_4027794_-	DUF333 domain-containing protein	NA	NA	NA	NA
WP_004213128.1\|4028056_4028308_-	ogr/Delta-like zinc finger family protein	A0A2I8TV89	Erwinia_phage	3.4e-08	49.2
WP_047724046.1\|4028351_4029491_-	phage late control D family protein	B9A7A9	Serratia_phage	2.7e-145	70.7
WP_047724047.1\|4029645_4030818_+\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	9.3e-157	70.2
WP_047724048.1\|4030817_4031333_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	1.3e-57	62.4
WP_047724049.1\|4031378_4031696_+	hypothetical protein	A0A0A7NPZ0	Enterobacteria_phage	2.2e-12	46.8
WP_053086776.1\|4031716_4031854_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	5.8e-10	65.9
WP_047724050.1\|4031840_4034816_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	6.8e-220	46.5
WP_000019450.1\|4035388_4036369_-\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_047724052.1\|4039393_4040317_-\|plate	baseplate J/gp47 family protein	A0A0A7NPY5	Enterobacteria_phage	1.9e-51	42.9
WP_024359484.1\|4040318_4040669_-	GPW/gp25 family protein	A0A0A7NQ90	Enterobacteria_phage	2.7e-27	55.7
WP_032437020.1\|4040665_4041253_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	9.1e-60	60.0
WP_047724053.1\|4041249_4041885_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	1.3e-56	51.0
WP_047724054.1\|4041881_4042349_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	3.5e-46	58.8
WP_128316295.1\|4042349_4042541_-	peptidase	NA	NA	NA	NA
WP_049070297.1\|4042530_4042860_-	DUF2570 domain-containing protein	NA	NA	NA	NA
WP_047724055.1\|4042871_4043417_-	lysozyme	Q1I0Z1	Pasteurella_virus	2.8e-31	43.0
WP_047724056.1\|4043413_4043698_-	hypothetical protein	NA	NA	NA	NA
WP_047724057.1\|4043688_4043889_-\|tail	tail protein X	A0A0A7NV57	Enterobacteria_phage	7.9e-16	61.5
WP_047724058.1\|4043888_4044404_-\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	4.8e-41	50.0
WP_047725084.1\|4044516_4045374_-\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	3.4e-71	58.0
WP_047724059.1\|4045423_4046458_-\|capsid	phage major capsid protein, P2 family	A0A0M3ULA3	Salmonella_phage	1.5e-94	49.1
WP_047724060.1\|4046467_4047307_-\|capsid	GPO family capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	1.3e-96	67.0
WP_047724061.1\|4047463_4049191_+	helix-turn-helix domain-containing protein	A0A0A7NV54	Enterobacteria_phage	1.9e-227	66.7
WP_047724062.1\|4049184_4050246_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	1.2e-142	68.7
WP_047724063.1\|4050855_4052466_+	AAA family ATPase	Q2P9X8	Enterobacteria_phage	7.9e-13	22.3
WP_047724064.1\|4052467_4053574_+	hypothetical protein	NA	NA	NA	NA
WP_077258085.1\|4053689_4054289_-	hypothetical protein	NA	NA	NA	NA
WP_032425611.1\|4054229_4055261_+\|transposase	IS630-like element ISEc33 family transposase	NA	NA	NA	NA
WP_047724066.1\|4055679_4056096_+	HNH endonuclease	NA	NA	NA	NA
WP_000019450.1\|4056141_4057122_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_047724067.1\|4057179_4057473_+	hypothetical protein	NA	NA	NA	NA
WP_000019450.1\|4057513_4058494_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_171972748.1\|4058475_4058913_+	hypothetical protein	NA	NA	NA	NA
WP_047724068.1\|4059026_4059545_-	hypothetical protein	NA	NA	NA	NA
WP_047724069.1\|4059547_4062097_-	replication endonuclease	A0A1S6L028	Salmonella_phage	2.0e-249	59.2
WP_047724070.1\|4062113_4063070_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A0M4QWR0	Salmonella_phage	1.5e-83	53.8
WP_004213098.1\|4063865_4064090_-	hypothetical protein	NA	NA	NA	NA
WP_047724071.1\|4064158_4064431_-	hypothetical protein	NA	NA	NA	NA
WP_032432798.1\|4064446_4064824_-	hypothetical protein	NA	NA	NA	NA
WP_004131515.1\|4064839_4065058_-	hypothetical protein	A0A0M5M1I3	Salmonella_phage	4.7e-06	49.1
WP_023339925.1\|4065078_4065357_-	regulatory phage cox family protein	Q1JS60	Enterobacteria_phage	2.4e-42	87.8
WP_048024533.1\|4065478_4065778_+	helix-turn-helix transcriptional regulator	Q1JS83	Enterobacteria_phage	3.0e-43	85.9
WP_047724072.1\|4065893_4066877_+\|integrase	tyrosine-type recombinase/integrase	Q83VS6	Escherichia_phage	6.4e-151	80.4
WP_047724073.1\|4067139_4068153_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_004101234.1\|4068210_4068312_+	YoaK family small membrane protein	NA	NA	NA	NA
WP_142988940.1\|4068311_4068386_+	protein YoaJ	NA	NA	NA	NA
WP_086074258.1\|4068526_4068652_+	hypothetical protein	NA	NA	NA	NA
WP_004131510.1\|4068700_4068964_-	DUF2534 family protein	NA	NA	NA	NA
WP_025106941.1\|4069093_4069732_-	leucine efflux protein LeuE	NA	NA	NA	NA
WP_004138325.1\|4069822_4070737_-	kdo(2)-lipid IV(A) palmitoleoyltransferase	A0A1W6JP29	Morganella_phage	4.5e-74	51.2
WP_047724074.1\|4071280_4072069_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014838169.1\|4072328_4072850_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_047724075.1\|4072846_4073794_+	fec operon regulator FecR	NA	NA	NA	NA
WP_047724076.1\|4073892_4076229_+	TonB-dependent receptor family protein	NA	NA	NA	NA
WP_047724077.1\|4076287_4077190_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014228931.1\|4077186_4078185_+	iron-dicitrate ABC transporter permease FecC	A0A2H4IY97	uncultured_Caudovirales_phage	5.4e-12	24.1
WP_047724078.1\|4078181_4079135_+	Fe(3+) dicitrate ABC transporter permease subunit FecD	NA	NA	NA	NA
4078509:4078526	attR	NA	NA	NA	NA
WP_047724079.1\|4079135_4079903_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	8.9e-15	26.7
WP_047724080.1\|4079939_4080983_-	type II asparaginase	NA	NA	NA	NA
WP_047724081.1\|4081262_4082453_+	HD domain-containing protein	NA	NA	NA	NA
WP_025106933.1\|4082530_4084315_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	7.3e-20	37.2
WP_004131480.1\|4084459_4085710_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	4.4e-19	90.7
WP_047724082.1\|4085946_4086597_+	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_025106932.1\|4086617_4087094_+	NUDIX hydrolase	NA	NA	NA	NA
WP_032749565.1\|4087132_4088239_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA

DBSCAN-SWA_13

4339802 : 4451933

112

Enterobacteria_phage(14.06%)

capsid,protease,holin,terminase,tRNA,plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004100829.1\|4339802_4340462_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	3.8e-46	53.9
WP_004849563.1\|4340550_4340880_+	sulfurtransferase TusE	NA	NA	NA	NA
WP_004849561.1\|4340876_4341158_-	acylphosphatase	NA	NA	NA	NA
WP_047725097.1\|4341207_4341996_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014228676.1\|4342012_4342567_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_009651924.1\|4342758_4343961_+	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_009651933.1\|4344021_4344339_+	heat shock protein HspQ	NA	NA	NA	NA
WP_032749730.1\|4344797_4345499_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_047724145.1\|4345512_4346451_-	peptidase	NA	NA	NA	NA
WP_047724146.1\|4346493_4349637_-	glycosyltransferase	NA	NA	NA	NA
WP_004849542.1\|4349834_4351040_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_046877472.1\|4351036_4353184_-	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	1.6e-24	25.1
WP_025106164.1\|4353180_4354617_-	TolC family outer membrane protein	NA	NA	NA	NA
WP_047724147.1\|4354784_4366208_-	BapA prefix-like domain-containing protein	NA	NA	NA	NA
WP_032749742.1\|4366892_4368086_+\|transposase	IS4 family transposase	S5FM71	Shigella_phage	1.5e-141	63.7
WP_014228669.1\|4368130_4368544_-	CoA-binding protein	NA	NA	NA	NA
WP_014228668.1\|4368698_4369157_+	methylglyoxal synthase	NA	NA	NA	NA
WP_032695058.1\|4369185_4371240_-	DNA helicase IV	A7KV33	Bacillus_phage	2.7e-18	27.2
WP_004849527.1\|4371362_4371809_+	YccF domain-containing protein	NA	NA	NA	NA
WP_032749744.1\|4371826_4373962_+	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_046878167.1\|4373949_4374573_-	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_032749745.1\|4375035_4375545_+	cell division inhibitor SulA	NA	NA	NA	NA
WP_004849520.1\|4375898_4376969_+	porin OmpA	NA	NA	NA	NA
WP_014228663.1\|4377071_4377524_-	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_032749746.1\|4377709_4379467_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_004849514.1\|4379536_4380055_+	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_004100764.1\|4380119_4380287_-	ribosome modulation factor	NA	NA	NA	NA
WP_004849513.1\|4380542_4381106_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_004849511.1\|4381105_4382743_-	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_014228659.1\|4382732_4384001_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_004849507.1\|4384015_4385923_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	5.6e-50	29.3
WP_014228658.1\|4385935_4388041_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_047724148.1\|4388139_4389249_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_004849504.1\|4389245_4389788_-	cell division protein ZapC	NA	NA	NA	NA
WP_004130996.1\|4389956_4390967_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_009653287.1\|4391215_4391791_+	NADPH-dependent FMN reductase	NA	NA	NA	NA
WP_004849501.1\|4391847_4392639_+	aliphatic sulfonate ABC transporter permease SsuC	NA	NA	NA	NA
WP_014837971.1\|4392635_4393409_+	aliphatic sulfonates ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.1e-32	39.0
WP_014228655.1\|4393474_4396090_-	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	6.3e-20	22.8
WP_047724149.1\|4396348_4396657_-	hypothetical protein	I6PCW5	Cronobacter_phage	4.5e-18	44.9
WP_047724150.1\|4396822_4397080_+	hypothetical protein	NA	NA	NA	NA
WP_171972745.1\|4397109_4397286_-	hypothetical protein	NA	NA	NA	NA
WP_187116899.1\|4397293_4399831_-	hypothetical protein	A0A2K9VAJ3	Klebsiella_virus	3.9e-43	33.0
WP_047724152.1\|4399839_4400883_-	hypothetical protein	A0A077KC23	Edwardsiella_phage	3.8e-16	38.2
WP_047724153.1\|4400884_4401472_-	DUF2612 domain-containing protein	A0A077K9U8	Edwardsiella_phage	5.0e-34	43.4
WP_032693643.1\|4401464_4402697_-\|plate	baseplate J/gp47 family protein	A0A077KGW9	Edwardsiella_phage	3.0e-105	51.0
WP_001518114.1\|4402704_4403061_-	hypothetical protein	NA	NA	NA	NA
WP_032749742.1\|4403118_4404312_-\|transposase	IS4 family transposase	S5FM71	Shigella_phage	1.5e-141	63.7
WP_171972755.1\|4404449_4405388_-	hypothetical protein	A0A0P0ZBT0	Stx2-converting_phage	6.7e-81	71.8
WP_165795128.1\|4405494_4405671_-	hypothetical protein	NA	NA	NA	NA
WP_052959005.1\|4405767_4406409_+	helix-turn-helix domain-containing protein	H9C160	Pectobacterium_phage	3.8e-11	30.2
WP_000019450.1\|4406872_4407853_+\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_187116900.1\|4407891_4408344_-	hypothetical protein	NA	NA	NA	NA
WP_047724156.1\|4408343_4408931_-	hypothetical protein	A1Z003	Burkholderia_virus	1.7e-05	24.8
WP_047724157.1\|4408920_4409790_-	hypothetical protein	NA	NA	NA	NA
WP_047724158.1\|4409786_4410092_-	hypothetical protein	A0A077K9U4	Edwardsiella_phage	4.7e-20	48.5
WP_047724159.1\|4410093_4410933_-	hypothetical protein	A0A077KGW3	Edwardsiella_phage	4.5e-28	32.9
WP_047724160.1\|4410936_4412853_-	transglycosylase SLT domain-containing protein	A0A0M4REK7	Salmonella_phage	3.9e-43	38.1
WP_001518122.1\|4413054_4413531_-	hypothetical protein	A0A068CGG2	Acinetobacter_phage	5.5e-07	29.8
WP_019724823.1\|4413582_4413837_-	hypothetical protein	K7PM89	Enterobacteria_phage	2.3e-20	74.6
WP_047724161.1\|4413839_4414595_-	KilA-N domain-containing protein	K7PGT4	Enterobacteria_phage	4.7e-61	51.4
WP_047724162.1\|4414775_4415219_-	hypothetical protein	A0A077K9T0	Edwardsiella_phage	1.9e-17	33.1
WP_047724163.1\|4415218_4416700_-	DUF3383 domain-containing protein	Q2NPD0	Xanthomonas_phage	8.7e-59	34.2
WP_047724164.1\|4416703_4417255_-	hypothetical protein	NA	NA	NA	NA
WP_032453636.1\|4417236_4417605_-	hypothetical protein	Q6UJ26	Burkholderia_virus	9.5e-07	29.8
WP_014342915.1\|4417601_4418165_-	hypothetical protein	H9C0W2	Aeromonas_phage	2.4e-17	32.4
WP_047724165.1\|4418167_4418611_-	DUF4054 domain-containing protein	A0A1X9SF97	Acinetobacter_phage	6.7e-15	41.2
WP_047724166.1\|4418610_4418937_-	hypothetical protein	H9C0V9	Aeromonas_phage	3.6e-10	42.5
WP_047724167.1\|4418938_4419976_-	DUF2184 domain-containing protein	A0A219YBB0	Aeromonas_phage	3.2e-84	50.3
WP_001518133.1\|4419975_4420458_-	hypothetical protein	A0A219YBF2	Aeromonas_phage	4.5e-33	50.3
WP_077258087.1\|4420459_4422316_-	DUF2213 domain-containing protein	A0A219YCD3	Aeromonas_phage	4.6e-57	37.4
WP_047724168.1\|4422378_4423068_-\|capsid	minor capsid protein	H9C0V1	Aeromonas_phage	2.8e-60	50.9
WP_047724169.1\|4423120_4424641_-	DUF1073 domain-containing protein	A0A2R3UAL5	Myoviridae_environmental_samples	6.1e-100	43.3
WP_001518137.1\|4424641_4426318_-\|terminase	phage terminase large subunit	H9C191	Pectobacterium_phage	5.1e-249	74.3
WP_009308024.1\|4426319_4426805_-	DUF2280 domain-containing protein	H9C190	Pectobacterium_phage	1.3e-64	77.6
WP_009652631.1\|4427912_4428089_-	hypothetical protein	NA	NA	NA	NA
WP_047724170.1\|4428102_4428552_-	lysozyme	A0A0M4R365	Salmonella_phage	8.5e-58	69.8
WP_047724171.1\|4428535_4428880_-\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	1.5e-33	63.6
WP_047725108.1\|4429708_4430398_-	antiterminator	I6PDF8	Cronobacter_phage	4.9e-65	57.1
WP_047724172.1\|4430533_4430764_-	hypothetical protein	NA	NA	NA	NA
WP_047724173.1\|4430760_4430985_-	hypothetical protein	Q76H69	Enterobacteria_phage	2.6e-23	62.2
WP_047724174.1\|4430981_4431626_-	recombination protein NinG	S4TSR3	Salmonella_phage	4.3e-55	64.5
WP_071846128.1\|4431618_4431789_-	hypothetical protein	G8C7V4	Escherichia_phage	3.7e-14	67.3
WP_047724175.1\|4431781_4432231_-	recombination protein NinB	Q8VNP6	Enterobacteria_phage	6.3e-37	51.7
WP_047724176.1\|4432482_4432797_-	hypothetical protein	A0A220NQY7	Salmonella_phage	2.6e-05	35.0
WP_047724177.1\|4433575_4433767_-	hypothetical protein	NA	NA	NA	NA
WP_047725114.1\|4433766_4434324_-	ead/Ea22-like family protein	K7PJQ4	Enterobacteria_phage	1.2e-58	65.0
WP_009308001.1\|4434325_4434910_-	HNH endonuclease	A0A1W6DXY0	Salmonella_phage	2.0e-30	46.0
WP_047725119.1\|4434906_4435365_-	hypothetical protein	R9TME7	Aeromonas_phage	1.4e-07	33.5
WP_187116903.1\|4435655_4437071_-	AAA family ATPase	Q9MCT4	Escherichia_phage	2.2e-184	67.3
WP_047724179.1\|4437075_4437975_-	hypothetical protein	A0A0N7C1Z7	Escherichia_phage	4.9e-81	54.8
WP_004194002.1\|4437967_4438114_-	hypothetical protein	NA	NA	NA	NA
WP_047684216.1\|4438200_4438422_-	bacteriophage CII family protein	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
WP_047684213.1\|4438462_4438696_-	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	1.3e-17	52.7
WP_047684208.1\|4438823_4439513_+	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	1.5e-61	52.7
WP_047724180.1\|4439759_4440389_+	hypothetical protein	K7PKU5	Enterobacteria_phage	7.7e-57	52.4
WP_162487899.1\|4440508_4440634_+	hypothetical protein	NA	NA	NA	NA
WP_019704100.1\|4440626_4440821_+	hypothetical protein	NA	NA	NA	NA
WP_071846130.1\|4441409_4441805_+	hypothetical protein	NA	NA	NA	NA
WP_162934436.1\|4441798_4441942_+	hypothetical protein	NA	NA	NA	NA
WP_047724182.1\|4441935_4442595_+	exodeoxyribonuclease X	A0A1W5PTR6	Pseudoalteromonas_phage	1.0e-19	32.9
WP_047724183.1\|4442596_4443265_+	AAA family ATPase	G9L667	Escherichia_phage	6.3e-49	44.7
WP_047724184.1\|4443276_4443981_+	hypothetical protein	A0A088C400	Shewanella_sp._phage	3.0e-25	40.2
WP_032748397.1\|4443992_4444169_+	DUF1317 family protein	M1FJ61	Enterobacteria_phage	7.7e-07	50.0
WP_047724185.1\|4444165_4444822_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.5e-114	88.0
WP_047724186.1\|4444818_4445226_+	DUF2591 family protein	A0A1J0GUX1	Halomonas_phage	4.0e-06	39.0
WP_047724187.1\|4445443_4445683_+	DUF4222 domain-containing protein	H6WZF9	Escherichia_phage	8.3e-12	50.0
WP_015584784.1\|4445696_4445945_+	excisionase family protein	S4TND0	Salmonella_phage	9.5e-27	64.6
WP_047724188.1\|4445987_4447277_+	DUF3596 domain-containing protein	Q8W658	Enterobacteria_phage	1.2e-168	65.0
WP_025107499.1\|4447534_4448737_+	nicotinate phosphoribosyltransferase	A0A2L0UZQ6	Agrobacterium_phage	6.4e-44	31.1
WP_004849497.1\|4449040_4450441_+\|tRNA	asparagine--tRNA ligase	A0A2K9V902	Bandra_megavirus	5.0e-80	37.0
WP_000654805.1\|4450964_4451933_+\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	7.7e-181	96.9

DBSCAN-SWA_14

4506846 : 4519265

Bacillus_phage(22.22%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047724202.1\|4506846_4507815_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	6.1e-61	44.0
WP_014228628.1\|4507929_4509696_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	7.0e-23	25.3
WP_025108297.1\|4509696_4511418_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	W8CYL7	Bacillus_phage	2.8e-16	23.4
WP_025108296.1\|4511456_4512161_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_002211347.1\|4512440_4512659_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_032751944.1\|4512830_4513268_-\|transposase	IS200/IS605 family transposase	A0A0A8WIU6	Clostridium_phage	1.2e-13	31.2
WP_004100627.1\|4513449_4513680_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.4e-16	61.2
WP_004100628.1\|4514004_4514322_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	3.4e-13	45.7
WP_004849425.1\|4514352_4516635_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	2.8e-165	42.3
WP_032751944.1\|4516797_4517235_+\|transposase	IS200/IS605 family transposase	A0A0A8WIU6	Clostridium_phage	1.2e-13	31.2
WP_025108294.1\|4517318_4519265_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	9.4e-37	39.2

DBSCAN-SWA_15

5038308 : 5048816

Morganella_phage(28.57%)

tRNA,integrase

attL 5036681:5036694|attR 5046503:5046516

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5036681:5036694	attL	NA	NA	NA	NA
WP_047724287.1\|5038308_5041065_-	TOPRIM and DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	2.6e-290	56.5
WP_047724288.1\|5041064_5041283_-	hypothetical protein	NA	NA	NA	NA
WP_047724289.1\|5041275_5042007_-	host cell division inhibitor Icd-like protein	A0A1C9IHV9	Salmonella_phage	2.8e-18	56.7
WP_047724290.1\|5042003_5042183_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_047724291.1\|5042182_5042785_-	antirepressor protein	A0A1W6JPH8	Morganella_phage	4.9e-53	55.0
WP_071846174.1\|5042881_5043082_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	8.8e-07	43.4
WP_052959008.1\|5043354_5044113_-	hypothetical protein	NA	NA	NA	NA
WP_047724292.1\|5044257_5045472_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	1.2e-125	53.4
WP_004099791.1\|5046055_5046922_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	6.5e-30	34.8
5046503:5046516	attR	NA	NA	NA	NA
WP_025107125.1\|5046923_5047136_+	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_004848430.1\|5047430_5048816_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	1.0e-45	35.1

DBSCAN-SWA_16

5854682 : 5913754

Stx2-converting_phage(20.0%)

tRNA,transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047724631.1\|5854682_5858069_+\|holin	choline trimethylamine-lyase	A0A1S6UAD4	Serratia_phage	9.7e-05	45.0
WP_016807794.1\|5858125_5859073_+\|holin	choline TMA-lyase-activating enzyme	NA	NA	NA	NA
WP_016807793.1\|5859085_5859514_+	BMC domain-containing protein	NA	NA	NA	NA
WP_047724633.1\|5859510_5860131_+	phosphate propanoyltransferase	NA	NA	NA	NA
WP_047724635.1\|5860143_5860830_+	hypothetical protein	NA	NA	NA	NA
WP_014227744.1\|5860849_5861263_+	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_004108688.1\|5861280_5861610_+	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_004098218.1\|5861851_5861947_+	tryptophanase leader peptide	NA	NA	NA	NA
WP_004128455.1\|5862071_5863460_+	tryptophanase	NA	NA	NA	NA
WP_047724638.1\|5863598_5864855_+	tryptophan permease	NA	NA	NA	NA
WP_047724640.1\|5865061_5866069_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_047724642.1\|5866221_5867619_-	diguanylate cyclase	A0A127AWB9	Bacillus_phage	3.4e-20	38.9
WP_000019450.1\|5867894_5868875_-\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_004098195.1\|5869352_5870420_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_047724643.1\|5870416_5873146_+	ribosome-associated ATPase/putative transporter RbbA	A0A2H4PQG7	Staphylococcus_phage	2.3e-20	29.8
WP_032719924.1\|5873145_5874270_+	ABC transporter permease	NA	NA	NA	NA
WP_014227738.1\|5874309_5874627_-	hypothetical protein	NA	NA	NA	NA
WP_047724644.1\|5881025_5882150_+	cupin domain-containing protein	NA	NA	NA	NA
WP_014837294.1\|5882218_5883094_-	5'/3'-nucleotidase SurE	NA	NA	NA	NA
WP_038422856.1\|5883589_5884369_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_047724645.1\|5884453_5885797_+	outer membrane porin, OprD family	NA	NA	NA	NA
WP_042944202.1\|5885838_5887203_-	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	1.3e-45	30.4
WP_047724646.1\|5887768_5889418_+	signal transduction protein	NA	NA	NA	NA
WP_014227730.1\|5889562_5891014_+	MFS transporter	NA	NA	NA	NA
WP_047724648.1\|5891066_5892170_+	mandelate racemase/muconate lactonizing enzyme family protein	NA	NA	NA	NA
WP_025107484.1\|5892193_5893021_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_047724651.1\|5893014_5893926_+	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_047724652.1\|5893912_5894344_+	heme-binding protein	NA	NA	NA	NA
WP_004117622.1\|5894480_5895494_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_047724656.1\|5895704_5896736_-	DUF1176 domain-containing protein	NA	NA	NA	NA
WP_077258094.1\|5897210_5897915_+	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_032747696.1\|5898203_5898527_+	endoribonuclease SymE	NA	NA	NA	NA
WP_004098173.1\|5898673_5899108_+	VOC family protein	NA	NA	NA	NA
WP_016947617.1\|5899330_5900311_-\|transposase	IS5-like element ISKpn26 family transposase	NA	NA	NA	NA
WP_047724661.1\|5900473_5901217_+	hypothetical protein	NA	NA	NA	NA
WP_047724663.1\|5901393_5902191_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047724666.1\|5902334_5903180_-	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_047724668.1\|5903266_5903656_-	toxin CbtA	NA	NA	NA	NA
WP_171972752.1\|5903712_5904039_-	type IV toxin-antitoxin system YeeU family antitoxin	NA	NA	NA	NA
WP_047724679.1\|5904096_5904318_-	DUF987 domain-containing protein	NA	NA	NA	NA
WP_047724681.1\|5904331_5904811_-	DNA repair protein RadC	NA	NA	NA	NA
WP_047724684.1\|5904822_5905266_-	antirestriction protein	A0A2D0W9W4	Bordetella_phage	5.7e-14	33.6
WP_047725179.1\|5905345_5905594_-	DUF905 domain-containing protein	NA	NA	NA	NA
WP_047724685.1\|5905599_5906424_-	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	3.9e-40	35.8
WP_047724687.1\|5906667_5907489_-	hypothetical protein	NA	NA	NA	NA
WP_047724689.1\|5908126_5908759_+	inovirus Gp2 family protein	NA	NA	NA	NA
WP_047724690.1\|5908892_5909117_+	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_071846147.1\|5909573_5909972_+	hypothetical protein	NA	NA	NA	NA
WP_142988925.1\|5910027_5911256_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.0e-146	81.7
WP_004189163.1\|5911343_5911784_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	2.6e-19	60.3
WP_004189161.1\|5911780_5912131_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	5.2e-39	63.8
WP_047722925.1\|5912161_5913754_+\|transposase	IS66-like element ISKox1 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.6e-175	61.6

DBSCAN-SWA_17

5918738 : 5926651

Stx2-converting_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047724695.1\|5918738_5918927_+	hypothetical protein	A0A140XAG6	Dickeya_phage	1.0e-09	65.1
WP_047724697.1\|5918923_5920480_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	4.0e-163	56.1
WP_047724698.1\|5920499_5920847_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	3.5e-43	72.0
WP_047724700.1\|5920843_5921485_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.5e-12	35.7
WP_047724702.1\|5921552_5924654_-	multidrug efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.3e-59	22.4
WP_047724704.1\|5924685_5925822_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_071846149.1\|5925955_5926651_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.7e-28	35.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_CP011635

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011635_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011635_1

68011-68246

Orphan

Consensus_repeat	Method
CATTGGTCGAAAAGCATTTGCATGAATGGG	PILER-CR
AAAAGCANTTGCATGAATG	CRT

5 spacers

The CRISPR arrays of NZ_CP011635_1

>merge|NZ_CP011635|1|68011-68246|PILER-CR,CRT
AAAAGCATTTACATGAATGGAATAGTAAAAGTTGCCCTTGGTCGAAAAGCAACTGCATGAATGAGCCCGGAAAAGGTTCCTTTGGTCGAAAAGCATTTGCATGAATGGGTTTCGGATATGTGTCTTTGCTACAAAGGCATTTGCATGAATGAGGCTGGAAAAGGCGCATTGTTTGAAAAGCATTTGCATGAATGGGGCGACACACAGGATGTGGCTGAAAAGCACTTGTATCAATG

>NZ_CP011635|1|1|68011-68206|PILER-CR
AAAAGCATTTACATGAATGGAATAGTAAAA	GTTGCCCTTGGTCGAAAAGCAACTGCATGAATGAGCCCGGAAAAGGTTCCTTTGGTCG
AAAAGCATTTGCATGAATGGGTTTCGGATA	TGTGTCTTTGCTACAAAGGCATTTGCATGAATGAGGCTGGAAAAGGCGCATTGTTTG
AAAAGCATTTGCATGAATGGG

>NZ_CP011635|1|1|68011-68246|CRT
AAAAGCATTTACATGAATG	GAATAGTAAAAGTTGCCCTTGGTCG
AAAAGCAACTGCATGAATG	AGCCCGGAAAAGGTTCCTTTGGTCG
AAAAGCATTTGCATGAATG	GGTTTCGGATATGTGTCTTTGCTAC
AAAGGCATTTGCATGAATG	AGGCTGGAAAAGGCGCATTGTTTG
AAAAGCATTTGCATGAATG	GGGCGACACACAGGATGTGGCTG
AAAAGCACTTGTATCAATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011635.1\|WP_015063095.1\|62440_63160_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|199908
NZ_CP011635.1\|WP_185757620.1\|73716_74469_+\|protein-disulfide-isomerase-HtdT	unknown	unknown	gnl\|CDD\|239318
NZ_CP011635.1\|WP_015063094.1\|61352_62174_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011635.1\|WP_015063104.1\|71307_71748_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011635.1\|WP_015063101.1\|68917_69268_+\|ThrL	unknown	unknown	gnl\|CDD\|377786
NZ_CP011635.1\|WP_022652153.1\|71737_73096_+\|IncHI-type-conjugal-transfer-protein-TrhB	unknown	unknown	gnl\|CDD\|319756
NZ_CP011635.1\|WP_015063098.1\|66144_67020_+\|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	unknown
NZ_CP011635.1\|WP_022652152.1\|69279_70065_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377500
NZ_CP011635.1\|WP_001395480.1\|64098_65130_-\|IS630-like-element-ISEc33-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP011635.1\|WP_022652148.1\|63156_63357_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011635.1\|WP_015063109.1\|75437_78119_+\|IncHI-type-conjugal-transfer-ATPase-TrhC	unknown	unknown	gnl\|CDD\|274279
NZ_CP011635.1\|WP_015063093.1\|60492_61338_+\|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase	unknown	unknown	gnl\|CDD\|273146
NZ_CP011635.1\|WP_015063108.1\|74478_75429_+\|TraV-family-lipoprotein	unknown	unknown	gnl\|CDD\|370611
NZ_CP011635.1\|WP_022652145.1\|56866_57043_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011635.1\|WP_015063106.1\|73104_73611_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011635.1\|WP_022652146.1\|58999_60154_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275105
NZ_CP011635.1\|WP_015063103.1\|70067_71306_+\|type-F-conjugative-transfer-system-secretin-TraK	unknown	unknown	gnl\|CDD\|368991
NZ_CP011635.1\|WP_015063091.1\|57057_58734_-\|DUF4942-domain-containing-protein	unknown	unknown	gnl\|CDD\|372683
NZ_CP011635.1\|WP_015063100.1\|68545_68899_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011635.1\|WP_022652144.1\|54233_56621_-\|Ig-like-domain-repeat-protein	unknown	unknown	gnl\|CDD\|372704

Protein	Function_ID	Function_description	E-value
NZ_CP011635.1\|WP_015063095.1\|62440_63160_-\|hypothetical-protein	gnl\|CDD\|199908	cd10719, DnaJ_zf, Zinc finger domain of DnaJ and HSP40. Central/middle or CxxCxGxG-motif containing domain of DnaJ/Hsp40 (heat shock protein 40). DnaJ proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonin family. Hsp40 proteins are characterized by the presence of an N-terminal J domain, which mediates the interaction with Hsp70. This central domain contains four repeats of a CxxCxGxG motif and binds to two Zinc ions. It has been implicated in substrate binding.	0.000368454
NZ_CP011635.1\|WP_185757620.1\|73716_74469_+\|protein-disulfide-isomerase-HtdT	gnl\|CDD\|239318	cd03020, DsbA_DsbC_DsbG, DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds formed by DsbA and prevent aggregation of incorrectly folded proteins. DsbC and DsbG are kept in their reduced state by the cytoplasmic membrane protein DsbD, which utilizes the TRX/TRX reductase system in the cytosol as a source of reducing equivalents. DsbG differ from DsbC in that it has a more limited substrate specificity, and it may preferentially act later in the folding process to catalyze disulfide rearrangements in folded or partially folded proteins. Also included in the alignment is the predicted protein TrbB, whose gene was sequenced from the enterohemorrhagic E. coli type IV pilus gene cluster, which is required for efficient plasmid transfer.	1.2217e-20
NZ_CP011635.1\|WP_015063101.1\|68917_69268_+\|ThrL	gnl\|CDD\|377786	pfam07178, TraL, TraL protein. This family consists of several bacterial TraL proteins. TraL is a predicted peripheral membrane protein which is thought to be involved in bacterial sex pilus assembly. The exact function of this family is unclear.	0.000885487
NZ_CP011635.1\|WP_022652153.1\|71737_73096_+\|IncHI-type-conjugal-transfer-protein-TrhB	gnl\|CDD\|319756	cd16430, TraB, TraB is a homolog of VirB10 which forms part of core complex in Type IV secretion system (T4SS). This family contains TraB (VirB10 homolog) and a component of the type IV secretion system (T4SS), and similar proteins. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TraB is localized similarly to related proteins in other systems, but unlike in other systems, Neisseria gonorrhoeae TraB does not require the presence of other T4SS components for proper localization. It has been shown to be expressed with TraK (VirB9 homolog) at low levels in wild-type cells, suggesting that gonococcal T4SS may be present in single copy per cell and the small amounts of these proteins are sufficient for DNA secretion.	3.5155e-78
NZ_CP011635.1\|WP_022652152.1\|69279_70065_+\|hypothetical-protein	gnl\|CDD\|377500	pfam05309, TraE, TraE protein. This family consists of several bacterial sex pilus assembly and synthesis proteins (TraE). Conjugal transfer of plasmids from donor to recipient cells is a complex process in which a cell-to-cell contact plays a key role. Many genes encoded by self-transmissible plasmids are required for various processes of conjugation, including pilus formation, stabilisation of mating pairs, conjugative DNA metabolism, surface exclusion and regulation of transfer gene expression. The exact function of the TraE protein is unknown.	1.54508e-15
NZ_CP011635.1\|WP_001395480.1\|64098_65130_-\|IS630-like-element-ISEc33-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.20201e-17
NZ_CP011635.1\|WP_015063103.1\|70067_71306_+\|type-F-conjugative-transfer-system-secretin-TraK	gnl\|CDD\|368991	pfam06586, TraK, TraK protein. This family consists of several TraK proteins from Escherichia coli, Salmonella typhi and Salmonella typhimurium. TraK is known to be essential for pilus assembly but its exact role in this process is unknown.	9.97055e-09
NZ_CP011635.1\|WP_015063109.1\|75437_78119_+\|IncHI-type-conjugal-transfer-ATPase-TrhC	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	3.73374e-109
NZ_CP011635.1\|WP_015063108.1\|74478_75429_+\|TraV-family-lipoprotein	gnl\|CDD\|370611	pfam09676, TraV, Type IV conjugative transfer system lipoprotein (TraV). This entry includes TraV, which is a component of conjugative type IV secretion system. TraV is an outer membrane lipoprotein that is believed to interact with the secretin TraK. The alignment contains three conserved cysteines in the N-terminal half.	2.02424e-06
NZ_CP011635.1\|WP_015063091.1\|57057_58734_-\|DUF4942-domain-containing-protein	gnl\|CDD\|372683	pfam13708, DUF4942, Domain of unknown function (DUF4942). The function of this family is not known.	2.0231e-15
NZ_CP011635.1\|WP_022652146.1\|58999_60154_-\|hypothetical-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	0.00453379
NZ_CP011635.1\|WP_015063093.1\|60492_61338_+\|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase	gnl\|CDD\|273146	TIGR00571, DNA_adenine_methylase, DNA adenine methylase (dam). All proteins in this family for which functions are known are DNA-adenine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). The DNA adenine methylase (dam) of E. coli and related species is instrumental in distinguishing the newly synthesized strand during DNA replication for methylation-directed mismatch repair. This family includes several phage methylases and a number of different restriction enzyme chromosomal site-specific modification systems. [DNA metabolism, DNA replication, recombination, and repair].	2.60858e-68
NZ_CP011635.1\|WP_022652144.1\|54233_56621_-\|Ig-like-domain-repeat-protein	gnl\|CDD\|372704	pfam13750, Big_3_3, Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.	1.31106e-31

>NZ_CP011635.1|WP_015063098.1|66144_67020_+|RepB-family-plasmid-replication-initiator-protein
MSDNNELAHPFDVTNTDTGRTYQLSPNSSKSVQPIALLRLSVFTPVGTKEKRFRNFEVDASDELSSMELARSEGYDDIRITGLKLSMSTDFKCWLGCIMAFSKYGFASEKITLSFNEFAKMCGISSTNINKRTRSRFQEALANLASVVISFRDSKTERFTVTHLVQKAMIDPKKDTVELVGDPSMWELYRYDHKTLLSLQVLSVLAKKEAAQSLYIYFEAMPAGTLFVNMKRLRERLLLTTPVRTQNQIIRKAMLELKSIGYLEYQEVKKGRDIQFQIFKRSPKLALAKQS
>NZ_CP011635.1|WP_001395480.1|64098_65130_-|IS630-like-element-ISEc33-family-transposase
MPIIVPIPRGERRLMQKAIHKTRDKNHARRLTAMLMLHRGERVSDVARTLCCARSSVGRWINWFTHSGIEGLKSLPAGRSRRWPFEHICTLLRELIKHSPGDFGYQRSRWSTELLAIKINEITGCQLHAGTVRRWLPSAGLVWRRAAPTLRIRDPHKDEKMAVIHKALDECSAEHPVFYEDEVDIHLNPKIGADWQLRGQQKRVVTPGQNEKYYLAGALHSGTGKVSYVGGNSKSSALFIALLKHLKATYRRAKTITLIVDNYIIHKSRETQRWLKANPKFRVIYQPVYSPWVNHVERLWQALHDTITRNHQCRSMWQLLKKVRHFMETASPFPGGKHGQAKV
>NZ_CP011635.1|WP_022652148.1|63156_63357_-|hypothetical-protein
MDKIVHFTVINTFNDLLIAKASLDRNIVEINAGKRFDHFEEGHDQYVQKVTDALLIVEGRLENLKK
>NZ_CP011635.1|WP_015063095.1|62440_63160_-|hypothetical-protein
MKHSIFFTHDGYLLPAVVKPFHGNDGHYYAMITRECFACGGTGEIANAVCVTCNGSKTSPATEEKLVLKEGIEFLETIPEFRCNPDLDAWKRRHSGHLALLQADNSKFAVSISQQLNNNLFLTVRQLESFYSTYQPVSKDLPENADVPVEHSFSIGDVVSIDIIFTEVRAAFSKGSHSYFFTFTGKKQNDGFALTGNVQDHVLLGHSYHLSGRVRKIHYFDSVPYALLTVFKLTTKPSA
>NZ_CP011635.1|WP_015063094.1|61352_62174_-|hypothetical-protein
MQNDLGLGFICKSARASAKIISRKVTFPLNGSSTTKLTLTGLQCHPSCRFPFYQLSMLIHNQLADHAANVVDENAPFTVSINIHEWLSRARVAFIDYHGLRNTDKTAMITLDHLEELLTHLSTTLAVYIPYSKKRLNFSFLTSFTLIKTSQSYTLMFPGVLRPILVLLGGLIQEFMTEKLLKRRNTQLVIFEYLRKSRRHSHKITDIANALQLQTVNVRIMHVLTQLADLGLISFICEGKRGERSIEELQFIPYASRDHSEVLSFEEWISPID
>NZ_CP011635.1|WP_015063093.1|60492_61338_+|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase
MLKGEYALRKHTPIIKWAGGKTKLMPFISQHFPHDQSRRWVEPFIGGGAVFLNMFATDALLADSNPDLINLYRNIQRNKSAFIREVNLLAEREFDKEDYLKLRNTFNSTSLDDAPLQRAVLFYAMNRLGYNGLCRYNLKRKYSVPWGNRSKLTLDPQKVDYLSFRLSGVELTTADFGLTLESAGGCDQIYCDPPYDKISKTSFVSYDGIPFNKSAHVKLADMLVAAHRKGASVAISNSLTPFTLELYEERGFEIHTLNAYRSVGSQSKSRKKEKEILAVLR
>NZ_CP011635.1|WP_022652146.1|58999_60154_-|hypothetical-protein
MSDLMTDSQQTNSRVFKSPLVSFSTVTGSGRFVSGMKQFRDANPDLCNEVTEQKAWAINPSVVQISPGFNSREMGMGEAYYQLPEVVDHLNNIKCAFIRGDYVDPIRVLIKDGIPYVCQGHCRLKAALMAQAEGHTDLTILCIEMKADEISCELTTIDGNRGLALSPVALGESYRRLQALGGWSLDRIAEREGKSSTTIAALIRLTGCSVYIKKLIHADAISYVAVLSLIDEFGETEAISRIEKMIAELEKADSSGIKIKKTPRGSIRVVPSDFKPARVPPVLATKAVEGVKLITTSLLQKLGDIQLPEVTDSSEDEEISFTLNRSMLEMLKNLQSEITEAENKQLRRVENRQARLKGEKVTYKSAKNTNTGGEPQSEAPPAQA
>NZ_CP011635.1|WP_015063091.1|57057_58734_-|DUF4942-domain-containing-protein
MSAVESNFPQIGAPGNSLVACMPLTGLSVNEDNFLPEMREELGIIASQVESYNEELSLLRSMSTQFMKYGNQKLYSYLSGYNHLISETDALYAENALRSEYWKRVMALTDVLSVMSDEKKNEWDKQFTADRYHRPPQEIPEFTLDAVVATVVTLLNDRHQFIKERVYAVFQSLSRHHKTNKAFGFSTRMITVGVCEGVKDKWVKLKVEFKESGLMPLSELRVICSYFRGETVKPVYDTKKMVENMVGHAGFRNWISLDGNSIRFRVYKNGSMHIDVHPDIAERLNNILAAIVPLALPTERLAHYKATLQEFPALKRCIDFHSRMQLAELEFTRNEKEWSSWTSLGYAGEFADKTRQVNAEVLRFLGARITSYHVTFDYDPTEVMRFIGHMGAMPDIVSHQFYPSSLRLSEYVASIIATGEGERLLEPSIGHGDLLQCFPKSVNVTGIELDTLNCLVSRAKGYDTTEADFLAWSAANPNQKFDCVVMNPPFADNRAKLHLLAAASHLVSGGRLAAVLPLSLQGIDNLLGEGYRAEWMDTFDNEFDNTAVSVRVLYVECL
>NZ_CP011635.1|WP_022652145.1|56866_57043_-|hypothetical-protein
MSEISPGLPEDQNDVEFMMDDFQQSLGKSKPVHEVQFLGESPQSEDSANAADSPWFEN
>NZ_CP011635.1|WP_022652144.1|54233_56621_-|Ig-like-domain-repeat-protein
MKCRAILLAPLIAFSFTAQAEIAELRFNDTQNQPKIVVPSVQWINPATSFEADVISGLDRYVQLSLLNVNGASLWSTKSSKVTVDDRMTSSSGYDYYGKRLSVPAFGEDNYTLREVITDLQNNEISRRDYVISIDRTPPKTSTIGYTRNGWQYGSEAIFTSVPSGMQYASVQALVFSGLSDSRSGLDRAEYFLVDSNGVERKRGAVINLVDNSVTVQNTTASDPALAPASQSEYRMGLYVYDKAGNKASVSRQSVIDRVNPPSVLQVLNTRTNTWENYSAGITVYSNPISLRVLRNKSNFTAANKTSFGWADANYQSSDSTYNIYSFNFVFPSTGDIYHEFQTLAGGVRRYHHSELSFTPSPTMELAPKVTSKEIFRSDTGKWSSATGNVRTAKFTQIRVTTEPRNYVQRVAANSNRNWYCLIPVGSTGCTMNVDYTFTSDKGMQYIHLVSGKDGTAIYDNLAGAFVVIWDNNPPVINAVKINRMDKNVTMTVTDDDRINGWQIGAWDTREFGVVLKTETGNVIDLPARTWTESDFKTKNAVISYADLPDGKYTVLSAYARDLVGNTANYVINDLLTIDSTAPLISYRYLNDDPEGKLVKGLENLRISVADPSGDASLESLVLSGGPNSEQVTLAYSSQGSGVYTPEYPRIFPVIAKEDGIYTIEAHAVDASGNRSSKKLNFLYQPANMITLDRLRTLATAAALKTTDNQPLAFIRTSVLRRKDGSVITGQLNGTLSVRKDADFPVSVAGVTVAPGETKAIIFDMGQGEERIYSVTPGKSGVSGTSEFAVEFPQF
>NZ_CP011635.1|WP_015063100.1|68545_68899_+|hypothetical-protein
MELTLNTNVEREQTNAFAFLKSKHAKVPLFILLFLASCGLAYAGSDDGAFGDIWAYMSEALTGAPGKIIACGMLFSVAYFGVVKPNLGLALVSALMMLIMANGEKIISTFLDAGIPL
>NZ_CP011635.1|WP_015063101.1|68917_69268_+|ThrL
MRGIFPLSGVFMTSQYEVPPHTYRFPYRINMPLLILFWDAKQLGITFVTIASGNIFDFFITSVVVAVVFWFAYKKAAEEGVRGKLKHKLWWFGLFPGKSVFSSRYFTDPFIRNLYS
>NZ_CP011635.1|WP_022652152.1|69279_70065_+|hypothetical-protein
MKLLSKLKIPFIKSASNGDFDKKDETSQNGGEDSKGRFRDSKARFSKEIEASEIGITYSALIKRDEKLLRVNSIAILVIAVLVVKNQFLTDPVTIVLPPNMTEEVKVVGNKASESYKTQWALFFSTLIGNINPTNIGFVTTTILDALSPDLQAKTRESLQQQTNIMQARGVEQSFKPIDMYYDTKNDMVYVWGTKSTRLINVPDKTESSKWTFEWVLGMKNGRPRIAYVNQYSGTPNIKKITINGKEQLATLDNPPPSTGN
>NZ_CP011635.1|WP_015063103.1|70067_71306_+|type-F-conjugative-transfer-system-secretin-TraK
MTSKKGFRCHAITAMILLATSNVVFAEDYQLPATVNNPVVMPVGADEFQNGVKNAIIKESGTGPAPETSQATKPTTELPSLSPASSASPAVNEITGALSKNPTLVGYQQQVKSGNFDSYGRPAGKEPQQNAQSTGAPSKADELYVEARNRYKEVQRVNVPPGGNIVLPVSRGLQNRISTSFKNASVSTSTPGDEASIFVNGGDVFISTNTDKPIGIMLSEDSVPESTYNLTLVPLDVPGAMISVTTSLSPTMQAKRETSLDKHNYDEMLARSQSEELAPSDPRQDDHKQRIIDLLTPVALGEVPSGFSLQEDRLSRIPSSEQSPCNFNMYSKLGQRLVGSRELIDVILVKNDKPYGQVVADQQCITEGVIASALFDKAFLQPGEETELYIVRDKLFKERQTRVTTRPSLIKR
>NZ_CP011635.1|WP_015063104.1|71307_71748_+|hypothetical-protein
MRKATFLTGVSFGLVVFLGTSYYYQTEYIPKGTVNIVPDDHRPGETVDDAFEEHTIIISDPTLAQKFVGSSTEFESRRGVKEIKEVGSLNNGKDFAPVESDNSGLNFKDKWPRAGEPYIVPQMTENERNLKVKRFQQPKSGVNNGH
>NZ_CP011635.1|WP_022652153.1|71737_73096_+|IncHI-type-conjugal-transfer-protein-TrhB
MDIKNAWENKTVRISVIGAALIVLIIVISQSIFSTPVKKEKKTQKKDMQTGFLIDDSQMTKLSNEESQKTYNEMVRQNRIDQNAAKADRDKAEKAQQESKVQIANLASQVQQLSTQLTDMQTSRNGNRNLDAGGSRKNVNEQAPATPYQLNPNAAVNGASSGYAPITPTRNSPMRTITQSSIKTNGSDGVIQVMPISESRIREGREVVAGGDKAPTRTIRGDGTAPVDSKARHAARKDEMFLPATSIITGVLINGLEAPTSLSSKAEPMPVTMRIKKDIIMPNNFTMDLRDCNLLGSAVGDLASQRAYIRATSISCVNSKGKAFDVKLEAYAVSENDGKNGIRGNLISRNGNAIAGSAFAGGLSALAGSLSPSKVSSLNIDPNSTAEYQSPNIGALGALAGAGAAQGGLNRLVDYYTSIAEQQWPIVEVSPGRPITFIVQSGATIPTNLTSR
>NZ_CP011635.1|WP_015063106.1|73104_73611_+|hypothetical-protein
MENNIEPGTKSDSAENVKLEAAKPVGGIRTTKKVTLEIDIEKTLKYLMLAGLAVLFVIYGYKGASFVYESVKAMSNPSYQIAVLDMQTLRKEFNKQNPEPDLVQSKNNFENYFKALMKVYRSRGYLVIDASLAVTIPDNVQIVSYIDLGGSFGEVQSLQGETKESEIR
>NZ_CP011635.1|WP_185757620.1|73716_74469_+|protein-disulfide-isomerase-HtdT
MEKAKEGGVSTKPLEGVLAKMQSYKPKDVIYIPTGGLYLFQDERSQLMAVTTDGRYTITGGSVMDILQRKSVLSVEDVRKSYFINLDDAPFPLDTVALIPLGNPKLKRQAAIFITLDCDGCQDLIKKFYDEREKYRVDIILIPSPGEPKQELRQLWCSKEKGKVNDLDILRWLMGNKTDIEQRLLTKKEAETCPAEPLVGSLMLAGIYKLQGVPSVVRQDGLAGNGIPKDFDSWLKQSVEPLLKNPFATN
>NZ_CP011635.1|WP_015063108.1|74478_75429_+|TraV-family-lipoprotein
MNIKKVIFSALVVGSSSYLAGCTIGSSESECPGIEKGVVCKGPREVMELTNNRDDLSGLAEEEANSGKEKSAVNDSQYPAQISPPGAVQYPKSAVLVNKPVTYKTTQIKPAGQVPVMYDETLKMGAPTSTIGPRPISGVPVNSNVRMTTSYSSTGASGNPFIHPTADVMKQTTQVVSPAPVPRYVAPNSDISASKDLYSVNNGQPVNPTLSSGQIQQYRTQGYKQAVVAPEPLAVLQQGRVMRITFAPYTDDNDALNLPGFVYVNVKPQTWIAGKNSTSNPARIVPLQVQDAARENMQQQQRATKAVSSNGIIRQL
>NZ_CP011635.1|WP_015063109.1|75437_78119_+|IncHI-type-conjugal-transfer-ATPase-TrhC
MKSANIYNKELSRHQFGGFIPVYDQIPGTNYFLIDGNRLGFMFICNPSPGVFDNQQDVLAELFKMDFPTDTICQTSLTALPDLTLHLSAWSAVRGGRMEGHDKLKGDLLTAYQLDYYDRSLNEPLKPDHDKLMLRDFQIWMSFSIPLKSALPTEIEINRIDALYSDLISKLNTLGLFPHKVSAENWLYCMDKLMHPGKTSRWAEGHVEVNTMRRLNEQLNVPGRKYTVTENNFSSTTQSTDVSEHRYFKQLSVVKFPEHVNFGSMYELVVNWMNGRKTIFSPFMITQTVHFADPLKLARDNVRYKAITNKQASIPTVLTFCPRLKDMDNDYMAVTRELEDGARLLHSYLTFTVMGNSALDVQSAADQLKSFYLESRVKVADDSYIIFPSFVSCLPMCNDPKTILDLDRFEVVSNTGAAHMTPLFGPWKGNTDRPVLNLVSREGQLLGLDIFKTSASYNMVVGATSGAGKSFWVAYIINNYLGAGPRSNNLIHYRDTFEGFKNNAYDAFDPDGAQIFVVDVGRSYQGISEQYTNSQFIDFGKKPDFTLNPFAFLTDVTVADRVFDEAPVFNDDSNNNDEEKDKVAQTIMVLNQLKIMASEKGNIDDFQQSVMLQLIGDEYNESRKVGSTGSITGFARRCSAHEDKRIKDIGEQLGQWCEGGIYGNRFTEKLPPINFGSRFIVLELEELKGTPHLQTVVLMSIIQAAQHAMFIKKDGRRRLFILDEAWEYIRPDNASGSSNQSNQFFSSFLEAAWRRFRKTNCAGICITQSFEDYFTSSVGRALTANSPWKIIMKQEKESIEAMKANNYFSTTDAEYERMKNIRTIKRAFSEMLVRFENFQEICRLYVDRKMELCFTTDSTDRGKLWEIQSRLDCSYGEAIEILYEQEVASNAAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	44606-44663	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP026171	Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence	12234-12291	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	KP899803	Salmonella enterica strain 8025 plasmid p8025, complete sequence	170506-170563	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	CP009869	Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence	373193-373250	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	8002-8059	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP029142	Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence	199238-199295	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	301705-301762	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	326206-326263	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP026242	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence	226156-226213	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP009883	Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence	62866-62923	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP026196	Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence	197619-197676	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	106299-106356	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP026391	Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence	65023-65080	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	68032-68089	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NC_019360	Citrobacter freundii plasmid pNDM-CIT, complete sequence	222140-222197	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	KY320277	Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence	19209-19266	0	1.0
NZ_CP011635_1	1.1\|68041\|58\|NZ_CP011635\|PILER-CR	68041-68098	58	NZ_MF072964	Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence	1904-1961	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP026242	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence	226244-226300	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP009883	Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence	62954-63010	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	44519-44575	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP026171	Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence	12147-12203	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	KP899803	Salmonella enterica strain 8025 plasmid p8025, complete sequence	170419-170475	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP026196	Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence	197707-197763	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	CP009869	Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence	373106-373162	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	106387-106443	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	7915-7971	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP026391	Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence	65111-65167	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP029142	Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence	199151-199207	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	301618-301674	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	68120-68176	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NC_019360	Citrobacter freundii plasmid pNDM-CIT, complete sequence	222228-222284	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	KY320277	Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence	19297-19353	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	326119-326175	0	1.0
NZ_CP011635_1	1.2\|68129\|57\|NZ_CP011635\|PILER-CR	68129-68185	57	NZ_MF072964	Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence	1992-2048	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP026242	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence	226154-226178	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP009883	Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence	62864-62888	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	44641-44665	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP026171	Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence	12269-12293	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	KP899803	Salmonella enterica strain 8025 plasmid p8025, complete sequence	170541-170565	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP026196	Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence	197617-197641	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	CP009869	Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence	373228-373252	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	106297-106321	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	8037-8061	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP026391	Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence	65021-65045	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP029142	Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence	199273-199297	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	301740-301764	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	68030-68054	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NC_019360	Citrobacter freundii plasmid pNDM-CIT, complete sequence	222138-222162	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	KY320277	Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence	19207-19231	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	326241-326265	0	1.0
NZ_CP011635_1	1.3\|68030\|25\|NZ_CP011635\|CRT	68030-68054	25	NZ_MF072964	Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence	1902-1926	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP026242	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence	226198-226222	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP009883	Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence	62908-62932	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	44597-44621	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP026171	Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence	12225-12249	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	KP899803	Salmonella enterica strain 8025 plasmid p8025, complete sequence	170497-170521	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP026196	Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence	197661-197685	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	CP009869	Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence	373184-373208	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	106341-106365	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	7993-8017	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP026391	Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence	65065-65089	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP029142	Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence	199229-199253	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	301696-301720	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	68074-68098	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NC_019360	Citrobacter freundii plasmid pNDM-CIT, complete sequence	222182-222206	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	KY320277	Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence	19251-19275	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	326197-326221	0	1.0
NZ_CP011635_1	1.4\|68074\|25\|NZ_CP011635\|CRT	68074-68098	25	NZ_MF072964	Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence	1946-1970	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	44553-44577	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP026171	Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence	12181-12205	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	KP899803	Salmonella enterica strain 8025 plasmid p8025, complete sequence	170453-170477	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	CP009869	Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence	373140-373164	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	7949-7973	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP029142	Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence	199185-199209	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	301652-301676	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	326153-326177	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP026242	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence	226242-226266	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP009883	Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence	62952-62976	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP026196	Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence	197705-197729	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	106385-106409	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP026391	Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence	65109-65133	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	68118-68142	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NC_019360	Citrobacter freundii plasmid pNDM-CIT, complete sequence	222226-222250	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	KY320277	Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence	19295-19319	0	1.0
NZ_CP011635_1	1.5\|68118\|25\|NZ_CP011635\|CRT	68118-68142	25	NZ_MF072964	Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence	1990-2014	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP026242	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence	226286-226309	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP009883	Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence	62996-63019	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	44510-44533	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP026171	Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence	12138-12161	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	KP899803	Salmonella enterica strain 8025 plasmid p8025, complete sequence	170410-170433	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP026196	Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence	197749-197772	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	CP009869	Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence	373097-373120	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	106429-106452	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	7906-7929	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP026391	Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence	65153-65176	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP029142	Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence	199142-199165	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	301609-301632	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	68162-68185	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NC_019360	Citrobacter freundii plasmid pNDM-CIT, complete sequence	222270-222293	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	KY320277	Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence	19339-19362	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	326110-326133	0	1.0
NZ_CP011635_1	1.6\|68162\|24\|NZ_CP011635\|CRT	68162-68185	24	NZ_MF072964	Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence	2034-2057	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP026242	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence	226329-226351	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP009883	Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence	63039-63061	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	44468-44490	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP026171	Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence	12096-12118	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	KP899803	Salmonella enterica strain 8025 plasmid p8025, complete sequence	170368-170390	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP026196	Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence	197792-197814	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	CP009869	Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence	373055-373077	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	7864-7886	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP026391	Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence	65196-65218	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP029142	Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence	199100-199122	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	301567-301589	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	68205-68227	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NC_019360	Citrobacter freundii plasmid pNDM-CIT, complete sequence	222313-222335	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	KY320277	Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence	19382-19404	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	326068-326090	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_MF072964	Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence	2077-2099	0	1.0
NZ_CP011635_1	1.7\|68205\|23\|NZ_CP011635\|CRT	68205-68227	23	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	106472-106494	3	0.87

1. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

2. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP026171 (Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

3. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to KP899803 (Salmonella enterica strain 8025 plasmid p8025, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

4. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to CP009869 (Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

5. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

6. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP029142 (Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

7. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

8. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

9. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP026242 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

10. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP009883 (Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

11. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP026196 (Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

12. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

13. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP026391 (Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

14. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_CP011635 (Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

15. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NC_019360 (Citrobacter freundii plasmid pNDM-CIT, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

16. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to KY320277 (Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

17. spacer 1.1|68041|58|NZ_CP011635|PILER-CR matches to NZ_MF072964 (Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence) position: , mismatch: 0, identity: 1.0

atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	CRISPR spacer
atagtaaaagttgcccttggtcgaaaagcaactgcatgaatgagcccggaaaaggttc	Protospacer
**********************************************************

18. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP026242 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

19. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP009883 (Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

20. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

21. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP026171 (Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

22. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to KP899803 (Salmonella enterica strain 8025 plasmid p8025, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

23. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP026196 (Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

24. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to CP009869 (Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

25. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

26. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

27. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP026391 (Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

28. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP029142 (Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

29. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

30. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP011635 (Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

31. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NC_019360 (Citrobacter freundii plasmid pNDM-CIT, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

32. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to KY320277 (Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

33. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

34. spacer 1.2|68129|57|NZ_CP011635|PILER-CR matches to NZ_MF072964 (Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence) position: , mismatch: 0, identity: 1.0

tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	CRISPR spacer
tttcggatatgtgtctttgctacaaaggcatttgcatgaatgaggctggaaaaggcg	Protospacer
*********************************************************

35. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP026242 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

36. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP009883 (Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

37. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

38. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP026171 (Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

39. spacer 1.3|68030|25|NZ_CP011635|CRT matches to KP899803 (Salmonella enterica strain 8025 plasmid p8025, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

40. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP026196 (Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

41. spacer 1.3|68030|25|NZ_CP011635|CRT matches to CP009869 (Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

42. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

43. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

44. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP026391 (Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

45. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP029142 (Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

46. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

47. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP011635 (Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

48. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NC_019360 (Citrobacter freundii plasmid pNDM-CIT, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

49. spacer 1.3|68030|25|NZ_CP011635|CRT matches to KY320277 (Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

50. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

51. spacer 1.3|68030|25|NZ_CP011635|CRT matches to NZ_MF072964 (Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence) position: , mismatch: 0, identity: 1.0

gaatagtaaaagttgcccttggtcg	CRISPR spacer
gaatagtaaaagttgcccttggtcg	Protospacer
*************************

52. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP026242 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

53. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP009883 (Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

54. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

55. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP026171 (Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

56. spacer 1.4|68074|25|NZ_CP011635|CRT matches to KP899803 (Salmonella enterica strain 8025 plasmid p8025, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

57. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP026196 (Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

58. spacer 1.4|68074|25|NZ_CP011635|CRT matches to CP009869 (Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

59. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

60. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

61. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP026391 (Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

62. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP029142 (Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

63. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

64. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP011635 (Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

65. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NC_019360 (Citrobacter freundii plasmid pNDM-CIT, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

66. spacer 1.4|68074|25|NZ_CP011635|CRT matches to KY320277 (Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

67. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

68. spacer 1.4|68074|25|NZ_CP011635|CRT matches to NZ_MF072964 (Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence) position: , mismatch: 0, identity: 1.0

agcccggaaaaggttcctttggtcg	CRISPR spacer
agcccggaaaaggttcctttggtcg	Protospacer
*************************

69. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

70. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP026171 (Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

71. spacer 1.5|68118|25|NZ_CP011635|CRT matches to KP899803 (Salmonella enterica strain 8025 plasmid p8025, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

72. spacer 1.5|68118|25|NZ_CP011635|CRT matches to CP009869 (Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

73. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

74. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP029142 (Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

75. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

76. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

77. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP026242 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

78. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP009883 (Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

79. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP026196 (Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

80. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

81. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP026391 (Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

82. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_CP011635 (Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

83. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NC_019360 (Citrobacter freundii plasmid pNDM-CIT, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

84. spacer 1.5|68118|25|NZ_CP011635|CRT matches to KY320277 (Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

85. spacer 1.5|68118|25|NZ_CP011635|CRT matches to NZ_MF072964 (Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcggatatgtgtctttgctac	CRISPR spacer
ggtttcggatatgtgtctttgctac	Protospacer
*************************

86. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP026242 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

87. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP009883 (Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

88. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

89. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP026171 (Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

90. spacer 1.6|68162|24|NZ_CP011635|CRT matches to KP899803 (Salmonella enterica strain 8025 plasmid p8025, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

91. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP026196 (Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

92. spacer 1.6|68162|24|NZ_CP011635|CRT matches to CP009869 (Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

93. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

94. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

95. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP026391 (Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

96. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP029142 (Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

97. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

98. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP011635 (Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

99. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NC_019360 (Citrobacter freundii plasmid pNDM-CIT, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

100. spacer 1.6|68162|24|NZ_CP011635|CRT matches to KY320277 (Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

101. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

102. spacer 1.6|68162|24|NZ_CP011635|CRT matches to NZ_MF072964 (Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence) position: , mismatch: 0, identity: 1.0

aggctggaaaaggcgcattgtttg	CRISPR spacer
aggctggaaaaggcgcattgtttg	Protospacer
************************

103. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP026242 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

104. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP009883 (Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

105. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

106. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP026171 (Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

107. spacer 1.7|68205|23|NZ_CP011635|CRT matches to KP899803 (Salmonella enterica strain 8025 plasmid p8025, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

108. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP026196 (Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

109. spacer 1.7|68205|23|NZ_CP011635|CRT matches to CP009869 (Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

110. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

111. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP026391 (Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

112. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP029142 (Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

113. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

114. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP011635 (Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

115. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NC_019360 (Citrobacter freundii plasmid pNDM-CIT, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

116. spacer 1.7|68205|23|NZ_CP011635|CRT matches to KY320277 (Leclercia adecarboxylata strain Lec-476 plasmid pLec-476, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

117. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

118. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_MF072964 (Citrobacter freundii strain P10159 plasmid pP10159-4, complete sequence) position: , mismatch: 0, identity: 1.0

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggctg	Protospacer
***********************

119. spacer 1.7|68205|23|NZ_CP011635|CRT matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 3, identity: 0.87

gggcgacacacaggatgtggctg	CRISPR spacer
gggcgacacacaggatgtggggc	Protospacer
********************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

167566 : 205511

Enterobacteria_phage(28.57%)

integrase,transposase,tRNA

attL 156653:156667|attR 169869:169883

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
156653:156667	attL	NA	NA	NA	NA
WP_014603550.1\|167566_168766_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_022652191.1\|169079_169292_+	hypothetical protein	NA	NA	NA	NA
WP_015063153.1\|169468_170110_+	hypothetical protein	NA	NA	NA	NA
169869:169883	attR	NA	NA	NA	NA
WP_023307208.1\|171132_174030_-\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	5.5e-182	37.8
WP_000509966.1\|174124_174730_+	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	5.5e-20	35.3
WP_022652193.1\|175671_176064_+	hypothetical protein	NA	NA	NA	NA
WP_022652194.1\|176473_176704_+	hypothetical protein	NA	NA	NA	NA
WP_015063155.1\|176856_178062_+	hypothetical protein	NA	NA	NA	NA
WP_015063157.1\|179080_179488_+	hypothetical protein	NA	NA	NA	NA
WP_022652195.1\|179520_179724_+	hypothetical protein	NA	NA	NA	NA
WP_022652197.1\|180950_181205_+	hypothetical protein	NA	NA	NA	NA
WP_032610398.1\|181289_181601_+	hypothetical protein	NA	NA	NA	NA
WP_000227969.1\|182471_183548_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_012561110.1\|184135_184972_-	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_012561111.1\|185036_185435_-	VOC family protein	NA	NA	NA	NA
WP_017384070.1\|185478_186588_-	S-(hydroxymethyl)glutathione dehydrogenase	E3SJ82	Synechococcus_phage	4.9e-30	28.3
WP_017384071.1\|186622_186898_-	formaldehyde-responsive transcriptional repressor FrmR	NA	NA	NA	NA
WP_023280857.1\|188109_189093_+	oxidoreductase	NA	NA	NA	NA
WP_023280966.1\|189155_189812_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_017384073.1\|190235_190532_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_139156019.1\|191390_191543_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_001254932.1\|191916_193068_+\|transposase	IS30-like element IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-42	35.6
WP_101743360.1\|194119_195100_+	NAD(P)H-quinone oxidoreductase	NA	NA	NA	NA
WP_040113343.1\|196399_197329_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	1.4e-75	53.1
WP_000027057.1\|197942_198803_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001217881.1\|198985_199543_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
WP_004152391.1\|200656_202372_-	Tn3-like element Tn4401 family resolvase TnpR	NA	NA	NA	NA
WP_004152392.1\|202481_205511_+\|transposase	Tn3-like element Tn4401 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage