CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007687	Listeria monocytogenes strain L2625 chromosome, complete genome	3 crisprs	DinG,cas3,WYL,casR,DEDDh,csa3,csn2,cas2,cas1,cas9	0	8	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007687_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007687_1

206905-207056

Unclear

Consensus_repeat	Method
CCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP007687_1

>merge|NZ_CP007687|1|206905-207056|CRISPRCasFinder
CCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACACCGATGCTTCTCGGTTTTAATGCTCCTACTCCATCGGAACCGAGCTCATTCGAATTTCCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC

>NZ_CP007687|1|1|206905-207056|CRISPRCasFinder
CCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC	ACCGATGCTTCTCGGTTTTAATGCTCCTACTCCATCGGAACCGAGCTCATTCGAATTT
CCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007687.1\|WP_003725735.1\|209976_210309_-\|putative-heavy-metal-binding-protein	unknown	unknown	gnl\|CDD\|179228
NZ_CP007687.1\|WP_003722732.1\|204378_205911_+\|zinc-metalloproteinase-Mpl	unknown	unknown	gnl\|CDD\|225768
NZ_CP007687.1\|WP_003722731.1\|202458_204048_+\|cholesterol-dependent-cytolysin-listeriolysin-O	unknown	unknown	gnl\|CDD\|366559
NZ_CP007687.1\|WP_012952051.1\|213074_213659_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP007687.1\|WP_003722727.1\|197856_199230_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184643
NZ_CP007687.1\|WP_003733966.1\|208065_208935_+\|phosphatidylcholine-phospholipase-C	unknown	unknown	gnl\|CDD\|214813
NZ_CP007687.1\|WP_003722742.1\|213765_214326_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP007687.1\|WP_003722729.1\|200279_200993_-\|listeriolysin-O-transcriptional-regulator-PrfA	unknown	unknown	gnl\|CDD\|223736
NZ_CP007687.1\|WP_009930499.1\|210375_211050_-\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|378033
NZ_CP007687.1\|WP_003722739.1\|211126_212068_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|178836
NZ_CP007687.1\|WP_003722735.1\|209006_209330_+\|DUF5502-family-protein	unknown	unknown	gnl\|CDD\|340321
NZ_CP007687.1\|WP_003722740.1\|212361_212985_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_CP007687.1\|WP_003722723.1\|194151_194844_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP007687.1\|WP_012952056.1\|201263_202217_-\|phosphatidylinositol-specific-phospholipase-C	unknown	unknown	gnl\|CDD\|176497
NZ_CP007687.1\|WP_003722724.1\|194840_196049_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NZ_CP007687.1\|WP_003722726.1\|197161_197470_+\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_CP007687.1\|WP_003722736.1\|209464_209926_+\|YehR-family-lipoprotein	unknown	unknown	gnl\|CDD\|227145
NZ_CP007687.1\|WP_003722725.1\|196733_197042_+\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_CP007687.1\|WP_003722728.1\|199280_200237_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP007687.1\|WP_003722743.1\|214440_217980_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118

Protein	Function_ID	Function_description	E-value
NZ_CP007687.1\|WP_003725735.1\|209976_210309_-\|putative-heavy-metal-binding-protein	gnl\|CDD\|179228	PRK01119, PRK01119, putative heavy metal-binding protein.	8.98192e-61
NZ_CP007687.1\|WP_003722732.1\|204378_205911_+\|zinc-metalloproteinase-Mpl	gnl\|CDD\|225768	COG3227, LasB, Zinc metalloprotease (elastase) [Amino acid transport and metabolism].	3.90486e-139
NZ_CP007687.1\|WP_003722731.1\|202458_204048_+\|cholesterol-dependent-cytolysin-listeriolysin-O	gnl\|CDD\|366559	pfam01289, Thiol_cytolysin, Thiol-activated cytolysin.	1.50399e-178
NZ_CP007687.1\|WP_012952051.1\|213074_213659_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	9.33654e-10
NZ_CP007687.1\|WP_003722727.1\|197856_199230_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184643	PRK14354, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_CP007687.1\|WP_003733966.1\|208065_208935_+\|phosphatidylcholine-phospholipase-C	gnl\|CDD\|214813	smart00770, Zn_dep_PLPC, Zinc dependent phospholipase C (alpha toxin). This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium. Structure information: PDB 1ca1.	6.00128e-87
NZ_CP007687.1\|WP_003722742.1\|213765_214326_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	4.98809e-109
NZ_CP007687.1\|WP_003722729.1\|200279_200993_-\|listeriolysin-O-transcriptional-regulator-PrfA	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.59942e-12
NZ_CP007687.1\|WP_009930499.1\|210375_211050_-\|DNA-alkylation-repair-protein	gnl\|CDD\|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	1.81561e-21
NZ_CP007687.1\|WP_003722739.1\|211126_212068_-\|L-lactate-dehydrogenase	gnl\|CDD\|178836	PRK00066, ldh, L-lactate dehydrogenase; Reviewed.	0
NZ_CP007687.1\|WP_003722735.1\|209006_209330_+\|DUF5502-family-protein	gnl\|CDD\|340321	pfam17606, DUF5502, Family of unknown function (DUF5502). This is a family of unknown function found in Listeria.	5.76244e-49
NZ_CP007687.1\|WP_003722740.1\|212361_212985_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.38585e-63
NZ_CP007687.1\|WP_003722723.1\|194151_194844_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	7.27113e-121
NZ_CP007687.1\|WP_012952056.1\|201263_202217_-\|phosphatidylinositol-specific-phospholipase-C	gnl\|CDD\|176497	cd00137, PI-PLCc, Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C. This subfamily corresponds to the catalytic domain present in prokaryotic and eukaryotic phosphoinositide-specific phospholipase C (PI-PLC), which is a ubiquitous enzyme catalyzing the cleavage of the sn3-phosphodiester bond in the membrane phosphoinositides (phosphatidylinositol, PI; Phosphatidylinositol-4-phosphate, PIP; phosphatidylinositol 4,5-bisphosphate, PIP2) to yield inositol phosphates (inositol monosphosphate, InsP; inositol diphosphate, InsP2; inositol trisphosphate, InsP3) and diacylglycerol (DAG). The higher eukaryotic PI-PLCs (EC 3.1.4.11) have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains. They play a critical role in most signal transduction pathways, controlling numerous cellular events, such as cell growth, proliferation, excitation and secretion. These PI-PLCs strictly require Ca2+ for their catalytic activity. They display a clear preference towards the hydrolysis of the more highly phosphorylated PI-analogues, PIP2 and PIP, to generate two important second messengers, InsP3 and DAG. InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which then phosphorylates other molecules, leading to altered cellular activity. In contrast, bacterial PI-PLCs contain a single catalytic domain. Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. They participate in Ca2+-independent PI metabolism. They are characterized as phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) that selectively hydrolyze PI, not PIP or PIP2. The TIM-barrel type catalytic domain in bacterial PI-PLCs is very similar to the one in eukaryotic PI-PLCs, in which the catalytic domain is assembled from two highly conserved X- and Y-regions split by a divergent linker sequence. The catalytic mechanism of both prokaryotic and eukaryotic PI-PLCs is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This superfamily also includes a distinctly different type of eukaryotic PLC, glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC), an integral membrane protein characterized in the protozoan parasite Trypanosoma brucei. T. brucei GPI-PLC hydrolyzes the GPI-anchor on the variant specific glycoprotein (VSG), releasing dimyristyl glycerol (DMG), which may facilitate the evasion of the protozoan to the host#s immune system. It does not require Ca2+ for its activity and is more closely related to bacterial PI-PLCs, but not mammalian PI-PLCs.	6.12448e-116
NZ_CP007687.1\|WP_003722724.1\|194840_196049_+\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	4.34799e-62
NZ_CP007687.1\|WP_003722726.1\|197161_197470_+\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	5.03804e-54
NZ_CP007687.1\|WP_003722736.1\|209464_209926_+\|YehR-family-lipoprotein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	5.22035e-59
NZ_CP007687.1\|WP_003722725.1\|196733_197042_+\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	2.92652e-53
NZ_CP007687.1\|WP_003722728.1\|199280_200237_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP007687.1\|WP_003722743.1\|214440_217980_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0

>NZ_CP007687.1|WP_003722732.1|204378_205911_+|zinc-metalloproteinase-Mpl
MKSKLICIIMVIAFQAHFTMTVKADSVGEEKLQNNTQAKKTPADLKALPDSCEAKDFYKNFKILDMTKDKLGVTHYTLALSSGGYLTDNDEIKVHVTPDNKITFINGDLQQGQLRITNQIKITEKNAIEKAFEAIGQSEAHVKSYVGNPVKEKEIILNSRTKRLVYNIKLIFAEPEVASWIVQVDAETGAILKKQNMLSEVERADTHKDFQALGKGANRLLQRPLHVMKINDLFYLVDRTHKGLIRTFDLKHNTDTSFGKVVSNKTNMFTDPEFSSAVDAHFYASEVYEYYKNVHQLESLDGKGGEIDSFVHYGLNCNNAFWDGQEILYGDGDKKNFKPFSCAKTIVGHELTHAVIQYSAGLEYEGQSGALNESFADVFGYFIAPNHWLIGEDVCVRGSRDGRIRSIKDPDKYNQAAHMKDYESLPITEEGDWGGVHYNSGIPNKAAYNTITKLGKEKTEQLYFRALKYYLTKKSQFTDAKKALQQAAKDLYGEDASKKVAEAWEAVGVN
>NZ_CP007687.1|WP_003722731.1|202458_204048_+|cholesterol-dependent-cytolysin-listeriolysin-O
MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE
>NZ_CP007687.1|WP_012952056.1|201263_202217_-|phosphatidylinositol-specific-phospholipase-C
MYKIYLRRTLVLVLCFILCFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTNLAALSIPGTHDTMSYNGDITWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLNIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSRKFGMQFGAPNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
>NZ_CP007687.1|WP_003722729.1|200279_200993_-|listeriolysin-O-transcriptional-regulator-PrfA
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
>NZ_CP007687.1|WP_003722728.1|199280_200237_+|ribose-phosphate-diphosphokinase
MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
>NZ_CP007687.1|WP_003722727.1|197856_199230_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQDEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASKLMQRRINENHMRNGVTLVNPESTYIDIDVKIGQDTVIEPGVMLRGKTVIGDDCVVTSGSEIVNSVIGERVHVRTSSIFESKVGDDVQIGPYAHLRPESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPEDALGIARAKQDNKLGYAKHLNHGK
>NZ_CP007687.1|WP_003722726.1|197161_197470_+|septation-regulator-SpoVG
MQVTDVRLRRVETDGRMRAIASITLDEEFVVHDIRVIDGNNGLFVAMPSKRGVDGEFRDIAHPINSDTRAKIQEVVLAEYERVGEEEATAVTEEESESVSAE
>NZ_CP007687.1|WP_003722725.1|196733_197042_+|septation-regulator-SpoVG
MEITDVRLRRVETDGRMKAISSITIDGEFVIHDIRVIDGNEGLFVAMPSKRTPDGEFRDIAHPINSGTRAKIQEAVLAAYEVADEPAVNEESSADESIVEEN
>NZ_CP007687.1|WP_003722724.1|194840_196049_+|ABC-transporter-permease
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKSSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGDEKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGVIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
>NZ_CP007687.1|WP_003722723.1|194151_194844_+|ABC-transporter-ATP-binding-protein
MPKPLIDMKNLTKTYTLGGETFKALDDVTFTVEQGEFLSIVGPSGSGKSTLMNMIGCLDVPDEGSYHLDDVDVFKLSDNKLSEIRNKKIGFIFQQFNLLPKLSAFENVELPLIYAGLSVSAREKAAIECLEKVGLLEKRRNLPTQLSGGQQQRVAIARALAGKPQILLADEPTGALDSKTGKEVMGILQELNRAGNTIVMITHDPTIASYGTRSIRIQDGKLFHEEATQA
>NZ_CP007687.1|WP_003733966.1|208065_208935_+|phosphatidylcholine-phospholipase-C
MKFKKVVLGMCLTASVLVFPVTIKANACCDEYLQTPAAPHDIDSKLPHKLSWSADNPTNTDVNTHYWLFKQAEKILAKDVNHMRANLMNELKKFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDRDNTYLPGFANAKITGAKYFNQSVTDYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVAKRFCSDDVKDWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
>NZ_CP007687.1|WP_003722735.1|209006_209330_+|DUF5502-family-protein
MYIKGRLIFFFVMFVIALCSVLILLIIKISVWKDEPFHLSDAKEIECLGSCEIKNTNQKIHFFSIKENLFEEKGDIAGILNEDEQKVADKSIFIVILDDEKGIANEE
>NZ_CP007687.1|WP_003722736.1|209464_209926_+|YehR-family-lipoprotein
MKMLKKGTAVLFVMIMAVMLVACGDKEETKTYTLSQNGVDSKLTYTYKGDKVTKQTAENTMSYASLGVASKEDAEKMLKATSDKFQGIDGLKEKIEYKDDKAIETLEVDYTKISSEDMNKIPGMSSNGDTSKGISMEESAKMLESQGYKEVSK
>NZ_CP007687.1|WP_003725735.1|209976_210309_-|putative-heavy-metal-binding-protein
MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
>NZ_CP007687.1|WP_009930499.1|210375_211050_-|DNA-alkylation-repair-protein
MITFDQLDTELQALENPNTIKIFRNHGCPDSLDLYGLKIGDLKKIIRREKLTKNHELAVKLIESNNSDLIYLGLLAINPNKITTEQIEKWNIAFRETWSQLTFGLASIVSKRDDALLFAKTWIESDYDLTKSMGWQIYSEHINNLPEAETLLQRAKETLQTETNRTRYSMNGFIITCGIYKDDLHEKAMEAAKSVGKVHVNLGNTACKVPDAISYIEKARNRTK
>NZ_CP007687.1|WP_003722739.1|211126_212068_-|L-lactate-dehydrogenase
MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTEFPAWSHTTVGGLPITEWISEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
>NZ_CP007687.1|WP_003722740.1|212361_212985_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MATTLEVQKRETTQHSEVTRLRSEGKVPGIIYGYKSENVPVSVDSLELIKAVRDNGRNAVFSVTVDGKKLNVLLHEYQVDPLKDVLVHVDLLAVDMNEEVETDVRVVLVGDAPGVKAGGVLQQIIHDVKVSATPEKLPETIELDISSLEIGDVLTTNDLPENKDYVVQAEEEETVVTVSAPRAEEEPTTTEAPEPEAVHGKDEEPVE
>NZ_CP007687.1|WP_012952051.1|213074_213659_+|GNAT-family-N-acetyltransferase
MLDKSVPHISVIMVNHDATNYPEFHLPAGYFFCFYKDGLEEDWCRLQLETGQVLSMDSIRARFETEFGNEKEKLTKRCIFVKAPNGEIIGTAMLWDGNTFGKMESRIHWVAVLDSHGGKGIAKALLSKILGLNKSKFVYLTTQTGSYQAIYLYRKFGFEKYVGKTPENWKTVNFQEEKETAWQIIENKIAEHQA
>NZ_CP007687.1|WP_003722742.1|213765_214326_+|aminoacyl-tRNA-hydrolase
MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNIPIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVINYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
>NZ_CP007687.1|WP_003722743.1|214440_217980_+|transcription-repair-coupling-factor
MKGLQQLIYEQKDIRAVLNALDEKEKAQLVTGLTGSSRALFASVVEGASKRPVVFVTHNLYHAQKLYDDLLSLMDVDRLFLYPADELISSELSISSPELRGQRVEALDFLLSGKPGIVIVPVAGLRKMLPPVSLWKHFNISIVEGEEIDPDVLRQKLVTMGYTMSGMVNTPGEFSVRGGIIDIYPITEEFPIRIELFDTEVDSLRFFDVETQRSTTRVEEFRLLPATEIILDQSYYPDIVKRLEKKMMLTLNELKEQEDKQALIENLEEDLEMLRSGVKPDMFFKYIGLAYPDPASLFDYLPKNTAILLDEFGRILETEESLEREEAEWQTETLSRMETVRDVQVSHSFKKLLEGNHSPKIYLSLFQKQMASMRVSKTTNIVYKQMQQFHGQMNVLKTELESWHKNNYAVVILAPNLERAEKMQQTLTDYDMESTILKKESDVPKYGMVQFVIGTFQNGFELPLAKVAIISETELFNKKIKKVKKRQKLSNAERIQSYSELKVGDYVVHVNHGIARYVGMETLDINGVHKDYLLLVYQGEDKLFIPVDQLDLVQKYVGAEGKSPRLNKLGGAEWKRVKKKVQASVQDIADDLIKLYAEREAEKGYAFSADDEMQREFEEAFPYQETEDQLRSISEIKKDMERPRPMDRLLVGDVGYGKTEVALRAAFKAIMDGKQVAFLVPTTILAQQHFETMKERFQGFPIEIGLLSRFRTKKQQTETLKGMKNGTVDVVVGTHRLLSKDVEYQDLGLLIVDEEQRFGVTHKEKIKQMRSKIDVLTLTATPIPRTLHMSMLGVRDLSVIETPPANRFPVQTYVAEQNNVLVREAIERELARDGQVYYLYNRVESITQKADEISAMVPDARVATAHGQMGESELESVILSFLEGEFDVLVTTTIIETGVDIPNVNTLFVQDADRMGLSQLYQLRGRVGRWNRIAYAYFMYQKDKILREEAEKRLSAIKEFTELGSGFKIAMRDLSIRGAGNILGAQQHGFIDSVGFDLYSQMLKEAIEAKKPKEEQKQIVPVEIDIQADAYIPEYYITDGRQKIEMYKRFRNIETLSELEDLQSDMIDRFGEYPEEVEYLFTMTELKVHALEVGIESVKQEQNKITMLFSESGTAGIRGDIVMQIIGEFGRMVGVGMEGTQLKITINVQNKPLKEWLYQVKSLAEKLRGAMKEKASTEN

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Crispr_ID: NZ_CP007687_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007687_2

515431-515914

Orphan

I-A

Consensus_repeat	Method
GTTTTAGTTACTTATTGTGAAATGTAAAT	PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	CRISPRCasFinder

7 spacers

The CRISPR arrays of NZ_CP007687_2

>merge|NZ_CP007687|2|515431-515914|PILER-CR,CRISPRCasFinder
GTTTTAGTTACTTATTGTGAAATGTAAATAGCGTTTTTCTTTTTCGCTTCATTTGATAAATCTTCCGTTTTAGTTACTTATTGTGAAATGTAAATAGTATTTACTTAGACAAACGCGCTCAAATTGAGCATGTTTTAGTTACTTATTTTGAAATGTAAATACAGTCAGTTTGTGCTCATTCACTTGAACTGCATCTTTGTTTTAGTTACTTATTTTGAAATGTAAATAGCGCAACAGGTGCCATATACAAACTGCCTTTTTTTCGTTTTAGTTACTTATTGTGAAATGTAAATTTTTACATGGGAGTCAAAAGAGCAACTTAATATACTGTTTTAGTTACTTATTTTGAAATGTAAATGTTGGTAGGTTTAACCAAAGATGATCACCATGTCGTTTTAGTTACTTATTGTGAAATGTAAATATGTCCCACTGCTCAATTTTTAACGGGACTCCAGGTTTTAGTTACTTATTATGAAATGTAAAT

>NZ_CP007687|2|1|515431-515914|PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAAT	AGCGTTTTTCTTTTTCGCTTCATTTGATAAATCTTCC
GTTTTAGTTACTTATTGTGAAATGTAAAT	AGTATTTACTTAGACAAACGCGCTCAAATTGAGCAT
GTTTTAGTTACTTATTTTGAAATGTAAAT	ACAGTCAGTTTGTGCTCATTCACTTGAACTGCATCTTT
GTTTTAGTTACTTATTTTGAAATGTAAAT	AGCGCAACAGGTGCCATATACAAACTGCCTTTTTTTC
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTTACATGGGAGTCAAAAGAGCAACTTAATATACT
GTTTTAGTTACTTATTTTGAAATGTAAAT	GTTGGTAGGTTTAACCAAAGATGATCACCATGTC
GTTTTAGTTACTTATTGTGAAATGTAAAT	ATGTCCCACTGCTCAATTTTTAACGGGACTCCAG
GTTTTAGTTACTTATTATGAAATGTAAAT

>NZ_CP007687|2|2|515431-515914|CRISPRCasFinder
GTTTTAGTTACTTATTGTGAAATGTAAAT	AGCGTTTTTCTTTTTCGCTTCATTTGATAAATCTTCC
GTTTTAGTTACTTATTGTGAAATGTAAAT	AGTATTTACTTAGACAAACGCGCTCAAATTGAGCAT
GTTTTAGTTACTTATTTTGAAATGTAAAT	ACAGTCAGTTTGTGCTCATTCACTTGAACTGCATCTTT
GTTTTAGTTACTTATTTTGAAATGTAAAT	AGCGCAACAGGTGCCATATACAAACTGCCTTTTTTTC
GTTTTAGTTACTTATTGTGAAATGTAAAT	TTTTACATGGGAGTCAAAAGAGCAACTTAATATACT
GTTTTAGTTACTTATTTTGAAATGTAAAT	GTTGGTAGGTTTAACCAAAGATGATCACCATGTC
GTTTTAGTTACTTATTGTGAAATGTAAAT	ATGTCCCACTGCTCAATTTTTAACGGGACTCCAG
GTTTTAGTTACTTATTATGAAATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007687.1\|WP_003727295.1\|524478_525894_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP007687.1\|WP_003721301.1\|520838_521270_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP007687.1\|WP_003721294.1\|512846_514118_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NZ_CP007687.1\|WP_003721303.1\|522867_523683_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP007687.1\|WP_031665228.1\|521316_522747_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NZ_CP007687.1\|WP_003733191.1\|509936_510404_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP007687.1\|WP_003721286.1\|506483_507134_+\|transaldolase	unknown	unknown	gnl\|CDD\|223254
NZ_CP007687.1\|WP_003721292.1\|511476_512523_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
NZ_CP007687.1\|WP_012951245.1\|510829_511480_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NZ_CP007687.1\|WP_003721293.1\|512538_512832_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NZ_CP007687.1\|WP_003733192.1\|509306_509909_+\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223865
NZ_CP007687.1\|WP_003721297.1\|516991_517672_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153212
NZ_CP007687.1\|WP_003721290.1\|510420_510819_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007687.1\|WP_033920546.1\|518902_520738_+\|lmo0514-family-class-1-internalin	unknown	unknown	gnl\|CDD\|380190
NZ_CP007687.1\|WP_003727296.1\|523963_524332_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
NZ_CP007687.1\|WP_003733187.1\|518062_518521_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_CP007687.1\|WP_033920547.1\|516305_516884_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007687.1\|WP_003721298.1\|517696_518056_-\|Lin0512-family-protein	unknown	unknown	gnl\|CDD\|131113
NZ_CP007687.1\|WP_003721295.1\|514257_515193_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP007687.1\|WP_003733193.1\|507242_509303_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234

Protein	Function_ID	Function_description	E-value
NZ_CP007687.1\|WP_003727295.1\|524478_525894_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.97112e-80
NZ_CP007687.1\|WP_003721294.1\|512846_514118_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	7.01085e-178
NZ_CP007687.1\|WP_003721303.1\|522867_523683_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
NZ_CP007687.1\|WP_031665228.1\|521316_522747_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	6.70557e-100
NZ_CP007687.1\|WP_003733191.1\|509936_510404_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	2.76446e-37
NZ_CP007687.1\|WP_003721286.1\|506483_507134_+\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	1.40072e-62
NZ_CP007687.1\|WP_003721292.1\|511476_512523_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0
NZ_CP007687.1\|WP_003721297.1\|516991_517672_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	7.71833e-60
NZ_CP007687.1\|WP_003721293.1\|512538_512832_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.06007e-27
NZ_CP007687.1\|WP_003733192.1\|509306_509909_+\|SIS-domain-containing-protein	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	1.15952e-75
NZ_CP007687.1\|WP_003721298.1\|517696_518056_-\|Lin0512-family-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	5.62162e-67
NZ_CP007687.1\|WP_012951245.1\|510829_511480_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	8.25352e-108
NZ_CP007687.1\|WP_033920546.1\|518902_520738_+\|lmo0514-family-class-1-internalin	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	6.04732e-120
NZ_CP007687.1\|WP_003733187.1\|518062_518521_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	1.03599e-12
NZ_CP007687.1\|WP_003721295.1\|514257_515193_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	2.38027e-153
NZ_CP007687.1\|WP_003721301.1\|520838_521270_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
NZ_CP007687.1\|WP_003727296.1\|523963_524332_-\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	2.33548e-41
NZ_CP007687.1\|WP_003733193.1\|507242_509303_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	3.95572e-80

>NZ_CP007687.1|WP_003721295.1|514257_515193_+|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSSIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>NZ_CP007687.1|WP_003721294.1|512846_514118_+|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAVLSSIINMAIIFKIADWTQKDVEDVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>NZ_CP007687.1|WP_003721293.1|512538_512832_+|PTS-sugar-transporter-subunit-IIB
MKKKRIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>NZ_CP007687.1|WP_003721292.1|511476_512523_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSGEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKVLFFPE
>NZ_CP007687.1|WP_012951245.1|510829_511480_+|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLQVLEKNDIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNAELAKECTLAGADLIVVGSYLFEGDIEANLEKLAKGVLTE
>NZ_CP007687.1|WP_003721290.1|510420_510819_+|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMVVVMIYATTILYAKWTLAYYLPKKMSQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>NZ_CP007687.1|WP_003733191.1|509936_510404_+|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQNKEKLLAEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>NZ_CP007687.1|WP_003733192.1|509306_509909_+|SIS-domain-containing-protein
MDKQAILNNIHQTWQEEANAISRLPEVTSEEALVKTVEKIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGVTENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>NZ_CP007687.1|WP_003733193.1|507242_509303_+|BglG-family-transcription-antiterminator
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTSKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>NZ_CP007687.1|WP_003721286.1|506483_507134_+|transaldolase
MHLDSANLDDVKKIQASSIFKGITTNPSILVKEKCNRQTAINRILELTDKQVFVQTVGFTYEEILADARMLLTMFGKDKIAIKIPAHEAGTNVIDTLKKEDKTIQILGTAIYSADQAITAALAGADFVAPYVNRMSAANIDPFKEISQMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYSQMTNKVLAVEAIRVFNEDAVLYEK
>NZ_CP007687.1|WP_033920547.1|516305_516884_+|hypothetical-protein
MKKILVPILLLATILASCSSPNEKITKDTKISKTITIRADYKVPKDIKELEDDSANIVKVKFLQNKTIGKDGSTISEIEILTSYKGNLEKGSKVDISEPWYLSDGKYVAVENYIALDKEQEYTIFLGEKDKDTYPLSSLGYGKFGGSLKEDQAVLADFTILGEVQKFDFISENTEEVKNYQLIKEQVAGKYK
>NZ_CP007687.1|WP_003721297.1|516991_517672_+|type-1-glutamine-amidotransferase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKRTSDKLLFFPESLNVFHWHQDTFALPTGSTRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILRIDEAFITPGKYVQSVEVMREKDVPEDNKQMLEAILDYLINPKTI
>NZ_CP007687.1|WP_003721298.1|517696_518056_-|Lin0512-family-protein
MEQILFIQTGFGVDVHGQNITKAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADQLDEDTIRAIIPYGTVTIEKMAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>NZ_CP007687.1|WP_003733187.1|518062_518521_-|MarR-family-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTAAGKELENELGAAQRKQMSEIFTNSADTDGMHFTEVMEGYAKNRPGAAFIKDFKE
>NZ_CP007687.1|WP_033920546.1|518902_520738_+|lmo0514-family-class-1-internalin
MKKALKLFLATICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSINNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSINGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSSRLSITDDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMTSYTISSGTYDQYFDISHTLDLTADESFDYNQYDATSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITSDSQISYKKETTKSVDEFLKEIHGSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAINDRGQKADPVTVVVTVTTSDSGHVNPVPPTPEVKPTPQEETDQTIIPEPQSETTEDSVKEDQAKDGQAKSEEKADKTSLTTKENKVEKSEKTNQPKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>NZ_CP007687.1|WP_003721301.1|520838_521270_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NZ_CP007687.1|WP_031665228.1|521316_522747_-|CapA-family-protein
MKKLTYVIITGLVLVFIAGAFWITNSTNQSDQKATQTEPLKKTSPANVKTISSEAKKTLNSLASSGADKASISDLKQLIKELKSYPTEKNDSGVYLQNLTACLEAVKSYTTGKTDEKTLGKVYPAFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYKNCLPWFKSDDYTVINAESAFTNATKAENKKWRIKSDPAHVAFLPASGVEAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>NZ_CP007687.1|WP_003721303.1|522867_523683_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NZ_CP007687.1|WP_003727296.1|523963_524332_-|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAGFAETVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVAVLLV
>NZ_CP007687.1|WP_003727295.1|524478_525894_+|multidrug-efflux-MFS-transporter
MQQEATGGQKIRPIPIIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGFGGVVFAFSSAGESGWGSATVLVSIIVGGLALGLFVWRQLTMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQTNGLNQLPPKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAGQKAYMETAQGVGPEQMVASLTAGIQNAFVFGLIMACIGLLCSLFIRKAK

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Crispr_ID: NZ_CP007687_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007687_3

2632323-2633085

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CRT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	PILER-CR

11 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP007687_3

>merge|NZ_CP007687|3|2632323-2633085|CRISPRCasFinder,CRT,PILER-CR
TATGTGTTGATATTCAGAATAATGTAGCTCTAAAACCAAGTTAAAGATATCAACTACATTCAGACAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACAGCCTATATCCCCTTCAAAAATCTTATTGTGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACAAGCTATACAGCATTAGATCTAAAGAGCTGGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTCTTCCATTGTGATAAACTGATAAACTAAAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACAAAAAAGTATTAGTTGATTCATTTGAATATGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTGATAAATTGTCGCCAAGCTCATCCGTCTTGGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACAATGAGTAACCAGAGCCGAAGTCTCCACCTGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTAGACATAAACAGAGAGAAAGCATTAAATAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACATATTAATACCGCAGTAAAATTAAGCAATAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACCGATCACTGACATAAACGACACGAAAATCAGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAACTCCTGTTTCATATTTTAAATATGTGGATGCGTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC

>NZ_CP007687|3|3|2632323-2633085|CRISPRCasFinder
TATGTGTTGATATTCAGAATAATGTAGCTCTAAAAC	CAAGTTAAAGATATCAACTACATTCAGACA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AGCCTATATCCCCTTCAAAAATCTTATTGT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AAGCTATACAGCATTAGATCTAAAGAGCTG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCTTCCATTGTGATAAACTGATAAACTAAA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AAAAAAGTATTAGTTGATTCATTTGAATAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TGATAAATTGTCGCCAAGCTCATCCGTCTTG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AATGAGTAACCAGAGCCGAAGTCTCCACCT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TAGACATAAACAGAGAGAAAGCATTAAATA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATATTAATACCGCAGTAAAATTAAGCAATA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CGATCACTGACATAAACGACACGAAAATCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCCTGTTTCATATTTTAAATATGTGGATGC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC

>NZ_CP007687|3|1|2632323-2633085|CRT
TATGTGTTGATATTCAGAATAATGTAGCTCTAAAAC	CAAGTTAAAGATATCAACTACATTCAGACA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AGCCTATATCCCCTTCAAAAATCTTATTGT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AAGCTATACAGCATTAGATCTAAAGAGCTG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCTTCCATTGTGATAAACTGATAAACTAAA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AAAAAAGTATTAGTTGATTCATTTGAATAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TGATAAATTGTCGCCAAGCTCATCCGTCTTG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AATGAGTAACCAGAGCCGAAGTCTCCACCT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TAGACATAAACAGAGAGAAAGCATTAAATA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATATTAATACCGCAGTAAAATTAAGCAATA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CGATCACTGACATAAACGACACGAAAATCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCCTGTTTCATATTTTAAATATGTGGATGC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC

>NZ_CP007687|3|2|2632521-2633085|PILER-CR
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCTTCCATTGTGATAAACTGATAAACTAAA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AAAAAAGTATTAGTTGATTCATTTGAATAT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TGATAAATTGTCGCCAAGCTCATCCGTCTTG
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	AATGAGTAACCAGAGCCGAAGTCTCCACCT
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TAGACATAAACAGAGAGAAAGCATTAAATA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	ATATTAATACCGCAGTAAAATTAAGCAATA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	CGATCACTGACATAAACGACACGAAAATCA
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC	TCCTGTTTCATATTTTAAATATGTGGATGC
GTTTTGGTAGCATTCAAAATAACATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007687.1\|WP_033920896.1\|2630017_2630869_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NZ_CP007687.1\|WP_033921080.1\|2614515_2617503_-\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|225918
NZ_CP007687.1\|WP_033921082.1\|2614039_2614516_-\|DUF1641-domain-containing-protein	unknown	unknown	gnl\|CDD\|225283
NZ_CP007687.1\|WP_023548324.1\|2634203_2635070_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP007687.1\|WP_003727703.1\|2640663_2641101_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP007687.1\|WP_003733033.1\|2642047_2642845_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP007687.1\|WP_009932866.1\|2630890_2631313_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
NZ_CP007687.1\|WP_003733032.1\|2641295_2642042_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP007687.1\|WP_003723652.1\|2640249_2640642_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_CP007687.1\|WP_033920898.1\|2635070_2639075_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP007687.1\|WP_023548325.1\|2633213_2633876_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP007687.1\|WP_003733022.1\|2627152_2628181_-\|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl\|CDD\|378455
NZ_CP007687.1\|WP_003728531.1\|2642847_2643714_-\|energy-coupling-factor-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|237454
NZ_CP007687.1\|WP_014601166.1\|2620473_2621361_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP007687.1\|WP_033920894.1\|2628449_2629976_+\|GW-domain-containing-glycosaminoglycan-binding-protein	unknown	unknown	gnl\|CDD\|224619
NZ_CP007687.1\|WP_023548327.1\|2631434_2631797_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007687.1\|WP_003733258.1\|2618891_2620373_-\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP007687.1\|WP_003733027.1\|2633865_2634207_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP007687.1\|WP_023548322.1\|2639584_2640064_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007687.1\|WP_009931305.1\|2618001_2618844_+\|S-adenosyl-l-methionine-hydroxide-adenosyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224824

Protein	Function_ID	Function_description	E-value
NZ_CP007687.1\|WP_033920896.1\|2630017_2630869_-\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	1.01525e-171
NZ_CP007687.1\|WP_033921080.1\|2614515_2617503_-\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|225918	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only].	0
NZ_CP007687.1\|WP_033921082.1\|2614039_2614516_-\|DUF1641-domain-containing-protein	gnl\|CDD\|225283	COG2427, COG2427, Uncharacterized conserved protein [Function unknown].	8.85322e-28
NZ_CP007687.1\|WP_023548324.1\|2634203_2635070_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.40242e-129
NZ_CP007687.1\|WP_003733033.1\|2642047_2642845_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	5.34175e-53
NZ_CP007687.1\|WP_009932866.1\|2630890_2631313_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.95207e-42
NZ_CP007687.1\|WP_003733032.1\|2641295_2642042_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	2.82266e-128
NZ_CP007687.1\|WP_003727703.1\|2640663_2641101_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.08607e-102
NZ_CP007687.1\|WP_033920898.1\|2635070_2639075_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP007687.1\|WP_023548325.1\|2633213_2633876_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.58789e-114
NZ_CP007687.1\|WP_003733022.1\|2627152_2628181_-\|Mrp/NBP35-family-ATP-binding-protein	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	3.84035e-115
NZ_CP007687.1\|WP_003728531.1\|2642847_2643714_-\|energy-coupling-factor-ABC-transporter-ATP-binding-protein	gnl\|CDD\|237454	PRK13634, cbiO, cobalt transporter ATP-binding subunit; Provisional.	0
NZ_CP007687.1\|WP_014601166.1\|2620473_2621361_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.35403e-15
NZ_CP007687.1\|WP_033920894.1\|2628449_2629976_+\|GW-domain-containing-glycosaminoglycan-binding-protein	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	9.3517e-69
NZ_CP007687.1\|WP_003723652.1\|2640249_2640642_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	4.44953e-85
NZ_CP007687.1\|WP_003733258.1\|2618891_2620373_-\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.77224e-108
NZ_CP007687.1\|WP_003733027.1\|2633865_2634207_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.15214e-45
NZ_CP007687.1\|WP_009931305.1\|2618001_2618844_+\|S-adenosyl-l-methionine-hydroxide-adenosyltransferase-family-protein	gnl\|CDD\|224824	COG1912, COG1912, Uncharacterized conserved protein [Function unknown].	4.67495e-126

>NZ_CP007687.1|WP_023548327.1|2631434_2631797_-|hypothetical-protein
MKKTSIIFTFCALLLTACSTTTKEIPRQTTEATGTIEQVETESILIKNFKIKNDNNTPELSVRFHISEKYHDETGNKIKRTELNKNDNIKIILTKDFQIQETSPAQIDPKYVQKIILLNK
>NZ_CP007687.1|WP_009932866.1|2630890_2631313_-|MerR-family-transcriptional-regulator
MNIKQAADMFGLTVDTLRYYERVGVIPPVHRNESGYRDYKTSDLNWVYLVKNLRNAGLSVESLIEFATLAQLRETQNVEAAQKQVLVDQLKELDEKLAEMKQVRDLLVYKIDSYDSHIAQFKAGELNADNVEKLWERDKF
>NZ_CP007687.1|WP_033920896.1|2630017_2630869_-|aldo/keto-reductase
MKTVKLNNGVEVPILGFGTYQITDAAEAEQAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPFNDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQTANLAILRKEGVAIEAWAPFAEGKNDIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLAIFDFELTEADKEEIAGLNQGESQFFSHADPEMVKWMASRKLNV
>NZ_CP007687.1|WP_033920894.1|2628449_2629976_+|GW-domain-containing-glycosaminoglycan-binding-protein
MDRKFIKPGIILLIVAFLVVSINVGAETGGSRTAQVNLTTSQQAFIDEILPAAQDGYRDGKLLTSVTLAQAILESNWGESVLSQNSNNLFGIKGTYKGKSVSMGTMEASGSTTANFRVYPSWKESIEDHTALITENARYQDAVGETDYRKALQAIKDGGYATDPDYVSKLVAIIERYNLDKYDVIYDKIDSNQSLAAIGTVAENKEQEVIWSAPYNTENANKIGTLENYSGRNLEISWEAKTEKGLWYFIRENNKDIGWINSNALKISYHQKADENVHLTKYVDDLSAHVYRLPSPEKQFDNGTIAKYDRKALQVDKKITRGGYAWFRISEGEKVIGWVRADKLNDRLYDRITEQTSYDGYALVSKSATDNVWTAPFNTKNAEKLAPLADYNNEKLEIVTRAKAGNTLWYQFKVGGKFVGWASEKDLNVFYTPAKEEPVKQVAYVKDPTAKLYNKPVESTSTNPKAVGFYYGKLLAVDKTATILGEDWLHLKDSQNSLGWIKAIDINS
>NZ_CP007687.1|WP_003733022.1|2627152_2628181_-|Mrp/NBP35-family-ATP-binding-protein
MLNEQQITRLLYRLQDPVLEASLEETEGVLEVQVLEETANIKIALADPAVETDHFVHNIEELLTQFGVNEINIELEYLPAAVIDRIFQARDNILSEASETKFLAIASGKGGVGKSTVSANLAIALAQQGKKVGLLDADIYGFSIPVLLGTTESPHKENGQIIPVETHGIQMISMDFFVEQGEPVIWRGPMLGKMIKMFLEEVRWGKLDYLLIDLPPGTGDVALDIHTLIPKCNELIVTTPHYAAASVASRAGYMAAKNNHKIIGVIENMSYLTLADGQVLKVFGQGGGEKVAADLETQLLIQLPIEQPEPNGNGYVSALFNSSSTSGKAYKTLAEKIIPYLS
>NZ_CP007687.1|WP_014601166.1|2620473_2621361_-|TetR/AcrR-family-transcriptional-regulator
MKEKKQRIIKSAKEVFQKQGYLKTSVQDMVDAAGISKGTFYNYFTSKEELAIVIFKQEYSVLHQRLEYTMGLDGTKKDNFTECLKIIIHFYTENGEILNITFSQTMIDDDFNAFLQNVRLKNMEWVKYQLLEVYGEETKPYINDITMLLSGMAAMYVFASGSKNVNTGLIERAIPYVVRRLDALVKDILESGEIVFTEADTENLVPDQTMIRKKRLAKLREALEELNVGIENADIADSDKWQYKESMNALVGEINNNEAPRDFMVQGTLLYLKQHVPASLTKEVNKLEACVNGLL
>NZ_CP007687.1|WP_003733258.1|2618891_2620373_-|multidrug-efflux-MFS-transporter
MNSTAVERPVDVNGKSYSRSLLVVTMIIGAFVAILNQTLLATALPMIMDDLHITAATGQWLTTAFLLTNGIMIPITALLIEKISSKTLFITAMTVFTIGTIIASVAGSFPILLTGRIVQAAGAGIMMPLLQTIFLLIFPREKRGAAMGLMGLVIAFAPAIGPTLSGWIVDSYDWRVLFLILIPIAVIDIILAFFGMKKVVKLTDTKIDFLSIVMSSIGFGALLYGFSSAGNDGWGDTTVITMLIVGVVVIALFVWRQLVIDNPMLELHVFKYPVFSLSVILGSIVTMAMIGAEIVLPLYIQTIRGESALQSGLLLLPGAIIMGIMSPITGIIFDKIGAKWLTITGVTILTIGTIPFMFLTMDTPLWYIVVFYAVRFFGISMAMMPVSTAGMNALPNHLINHGSAVNNTIRQIAGSIGTAVLITVLTNVTKDNMPGKALMATDPASFAQKAQDASLDGMRAAFMVAAIFAAIGMILSLFLKTKKQEPIVKEYTK
>NZ_CP007687.1|WP_009931305.1|2618001_2618844_+|S-adenosyl-l-methionine-hydroxide-adenosyltransferase-family-protein
MTKQLLVLQSDFGISDGAVSAMYGVINSVSIDLQIYDLTHQIPQFNIWEASYRLLQTVTYWPEDTIFVSIVDPGVGSKRRSVAVLTEDGHYIITPDNGTLTHIAHYGTIKAVRLIDEEKNRLPKSGASHTFHGRDIFAYTAARLAAGVINFEDIGPAANPDSIVSLSLSDSYLEGDQAFGTIDIIDRPFGNLWTNIRRTDFFELGANYGDSIEVLIKHHDRIVYKNFVTYSRSFADLRIGEALIYVNSLDNLGLGINQGSFVDAYSVGTGTSWKVTLKKV
>NZ_CP007687.1|WP_033921080.1|2614515_2617503_-|formate-dehydrogenase-subunit-alpha
MGAKVSVQINGVARDVVEGTRILDYLNAEGIQHPHICYSEQIGPIQSCDTCMCEVDGELVRACSTNLTDGMEIKTNSELAKDAQLEAMDRILENHLLYCTVCDNNNGNCKVHNTTELLGVEKQERPYREKGYLNDFSHPFYRYDPDQCILCGRCVEACQQVQVNETLSIDWERSQPRVIWDDDRPANLSSCVSCGLCATVCPCNALMEKSMLGQAGFMTGLDEDMLEPMIDMVKKVEPNYQTVFAVSEMEAAMRETRTKKTKTVCTFCGVGCTFEVWTKDRKILKVEPTGEGPVNKFATCVKGKFGWDFVNSEKRITTPLIREGNEFVPASWEDAIHLVATKLREIQAKYGNDSLGFISSSKTTNEENYLMQKLARQVFETNNIDNCSRYCQAPASDGLTRTVGIGADSGTVEDIESAGLVIIVGASPADGHPVLASRIKRAQKTRGQKLIVSDLRKHEMAERSDLFIHPKQGTDFVWLTAVAKYMIDQGWHDEVFMENRISNVADYLAFLEPFTLEYAEKETGLSVETLKKVAQMVHEADGTAVCWGMGVTQNIAGSHTSSAIANLLLVTGNFGRHGAGAYPLRGHNNVQGACDMGSLPNVLPGIQPLGNDEVRARFEEAYGVSISPEPGLKNNEMLDAIEAGTLHSMYVIGEEMAWVDSNSNHVQEILASLDFFVVQDVFLSKTAQFADVVFPAAPSLEKEGTFTNTERRVQRLYEVLEPLGDSKPDWWIIQEVARACGRTDWNYDHPSEIMDEIASLAPFFAGVRYDRMQGFNSLVWPVSADGKDMPLLYEERFNFPDGKAQFSTLPYIAPITFPEEYNLTLNNGRLLEQFHEGNLTDKSKGLDYKLPEVFVEVSHELAKERDLESGSLVRLSSPYGRIKLRAVVTERMKGNEVYVPMHSVSSETAVNLLTSSAGDVRTKTPAYKQTKVNLTVLEKTGKNPLPDHNPRNRKRFPQNGAEVARKWSREDYQPISKVNCACGGNCGCGGKGRNH
>NZ_CP007687.1|WP_033921082.1|2614039_2614516_-|DUF1641-domain-containing-protein
MAEPISTIRDTKKTPEELEKERLEQMKADIAEQDSGFIEILETVKLLQESGALEALNSAIKARGDITKTFLNEWRKEPMTNAINNMMISSKLLTDTKPEQTEEMIANLKNAAKKAEESAKNNEIMGMLAMMKALKDPDINRALRYGVTFLKEVGQTLK
>NZ_CP007687.1|WP_023548325.1|2633213_2633876_-|type-II-A-CRISPR-associated-protein-Csn2
MNFNFKLLDEPITIEDSTIFVIEDVRVFANVAKLFYQYDETEELKVFNTKQHPLKSSELMLVTDILGHDINSAATLKLIYTDLEQQLNEKPEVKSMIDKLTATISELIGYELLEHELDLEEDEITVIELFKALGIKIETKSDTVFEKLIEIVQVYKYLSKKKLLVLINVCSYLTEEELLELRRYISLYQVKVLFIEPRKIKGSPQVTLDSDYFLHVENSI
>NZ_CP007687.1|WP_003733027.1|2633865_2634207_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMLLMFDMPTDTAKERKAYRQFRRFILSEGFIMHQYSVYSKILLNGTASKAMLARLKQQNPKKGLITLLTVTEKQFARMVYLSGEQNKSVGNSDARLIFLGDAIDEF
>NZ_CP007687.1|WP_023548324.1|2634203_2635070_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNSHSKLSYKNQHLVFKSAYQHEMIHLSEIDVLILETTDITLTTMLINCLVSENILILFCDDKRLPIGKVLPFYGRHDSSLQLSKQLGWDSELKSEVWTEIISQKILNQSTFLSMLDYDEKADSLIKLHETLEMFDPTNREGHAARIYFNQLFGNDFTREQENDINSGLNYGYTLLLSIFARELVKSGCMTQFGLKHSNQFNDFNFASDIMEPFRPLVDQIVYEKRAEDFQVIKRSLFELFNKQFDYNDQHMFLTNIASDYTKKVVKVLNEEREGVPEFRI
>NZ_CP007687.1|WP_033920898.1|2635070_2639075_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKNPYTIGLDIGTNSVGWAVLTNQYDLVKRKMKVAGNSDKKQIKKNFWGVRLFDDGQTAVDRRMNRTARRRIERRRNRISYLQEIFAVEMANIDANFFCRLNDSFYVDSEKRNSRHPFFATIEEEVAYHKNYRTIYHLREELVNSSEKADLRLVYLALAHIIKYRGNFLIEGALDTKNTSVDGVYEQFIQTYNQVFMSNIEEGTLAKVEENIEVANILARKFTRREKFERILQLYPGEKSTGMFAQFISLIVGSKGNFQKVFDLIEKTDIECAKDSYEEDLETLLAIIGDEYAELFVAAKNTYNAVVLSSIITVTDTETNAKLSASMIERFDAHEKDLVELKAFIKLNLPKQYEEIFSNAAIDGYAGYIDGKTKQVDFYKYLKTILENIEGADYFIAKIEEENFLRKQRTFDNGAIPHQLHLEELEAIIHQQAKYYPFLREDYEKIKSLVTFRIPYFVGPLAKGQSEFAWLTRKADGEIRPWNIEEKVDFGKSAVDFIEKMTNKDTYLPKENVLPKHSLCYQKYMVYNELTKIRYIDDQGKTNYFSGQEKQQIFNDLFKQKRKVKKKDLELFLRNINHVESPTIEGLEDSFNASYATYHDLMKVGIKQEILDNPLNTEMLEDIVKILTVFEDKRMIKEQLQQFSDVLDGTVLKKLERRHYTGWGRLSAKLLVGIRDKQSHLTILDYLMNDDGLNRNLMQLINDSNLSFKSIIEKEQVSTADKDLQSIVADLAGSPAIKKGILQSLKVVEELVSVMGYPPQTIVVEMARENQTTNKGKNNSKPRYKSLEKAIKEFGSQILKEHPTDNQELKNNRLYLYYLQNGKDMYTGQELDIHNLSNYDIDHIVPQSFITDNSIDNLVLTSSAGNREKGDNVPPLEIVQKRKIFWEKLYQGNLMSKRKFDYLTKAERGGLTEADKARFIHRQLVETRQITKNVANILHQRFNYKTDDNEDTMEPVRIVTLKSALVSQFRKQFQLYKVREVNDYHHAHDAYLNGVVANTLLKVYPQLEPEFVYGEYHQFDWFKANKATAKKQFYTNIMLFFAQKERIIDENGEILWDKKYLETIKKVLNYRQMNIVKKTEIQKGEFSNQNPKPRGDSSKLIPKKTNLNPIKYGGFEGSNMAYAIIIEHEKRKKKVTIEKKLIQINIMERKAFEKDEKVFLEGKGYHQPKVLTKLPKYALYECENGRRRMLGSANEVHKGNQMLLPNHLMTLLYHAEKREAIDGESLAYIEAHKAVFGELLAHISEFARKYTLANDKLDEINMLYERNKDGDVKSIAESFVSLKKFNAFGVHKDFNFFGTTIKRKRDRKLKELLNSTIIYQSITGLYESRKRLDS
>NZ_CP007687.1|WP_023548322.1|2639584_2640064_-|hypothetical-protein
MKSLIIHKMHSSYFTNMSEVFNLLPEGELNCMWLVSSYECNIYPSEQIPFDKDYVWLKGTKLKEILNQKEIMFIWGNFTSYSSDTELKDVLKYLIPFADGNKDLWGKNVQLSNPLSNTELISWDSSIFLALSKNTSIIELLKANYPDSEDLSMYNSDID
>NZ_CP007687.1|WP_003723652.1|2640249_2640642_-|30S-ribosomal-protein-S9
MAQVQYYGTGRRKSSVARVRLVPGDGKIVINNRDWEDYIPFAALREVIKQPLVATETLGNYDVLVNVHGGGYTGQAGAIRHGVARALLQVAPEYRPALKSAGLLTRDSRMKERKKPGLKGARRAPQFSKR
>NZ_CP007687.1|WP_003727703.1|2640663_2641101_-|50S-ribosomal-protein-L13
MRTTYMAKPGEVERKWYVIDATGVSLGRLSSEVASILRGKNKPQFTPHIDTGDFVIIINAGKIGLTGKKATDKIYYRHSQYPGGLKSRTAGEMRTNNPEKLLELSIKGMLPKNSLGRQLFKKLHVYGGSEHEHAAQQPEVYELRG
>NZ_CP007687.1|WP_003733032.1|2641295_2642042_-|tRNA-pseudouridine(38-40)-synthase-TruA
MTRYKAIISYDGSGFYGYQVQPNTRTVQAEIEKALTKMHKGKTVRVTASGRTDTGVHAKGQVIHFDSELDITAEKFQKALQVMTPFDISFLTVEEVPDDFHARFGTVGKEYRYVVKRTKIFDPFSRNFALHYPYELDISKMKLASKRLIGEHDFTSFCSARTERDSKVRTLYSIDFYEEDDETLVIAFQGNGFLYNMVRILTGTLLDAGQGRISPDDISEALLARDRQKLISKTAPPQGLYLWRVDYE
>NZ_CP007687.1|WP_003733033.1|2642047_2642845_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MMDKMILGRYIPGNSWLHRIDPRAKITAVMAFIAIVFLANNWLTYALMFVYVLYLVLTSKVPFLFFIKGLQPIFWLILITLLLQVFFTKGGTVLVDLGLLQITTLGLANGAMMFCRFVLIIFMTTLLTLTTSPIELTDGLEKILAPFRLVHLPVHELALMLSISLRFIPTLMDETEKILKAQKARGVEFTSGKWSDRIKAIIPLLVPLFISAFKRAEDLAIAMEARGYRGGKGRTRFRLLRWRFADTFLLISLAVLSGLLFWLRS
>NZ_CP007687.1|WP_003728531.1|2642847_2643714_-|energy-coupling-factor-ABC-transporter-ATP-binding-protein
MEIKLEQLGYCYQKNSPFEKRALLDVNVSFDSGSYSAIIGHTGSGKSTLLQHLNALLMPTEGKITVGDREIVAGVKQKKLRDLRKKVGIVFQFPEAQLFEETVEKDICFGPMNFGVSEEDAKLRAKKVIYEVGLTEEILSRSPFELSGGQMRRVAIAGVLAMDPEVLVLDEPTAGLDPHGREEIMEMFYNLHKEKGLTTVLVTHSMEDAARYAEKIVLMKAGTVLQIGTPREIFAKPDELVDLGLSVPDVVRFQGLFERKFDVKLTKTCLTIDELTTEMAPYLAKGGA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	DQ003642	Listeria phage A006, complete genome	25586-25615	0	1.0
NZ_CP007687_2	2.4\|515658\|37\|NZ_CP007687\|PILER-CR,CRISPRCasFinder	515658-515694	37	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	218117-218153	1	0.973
NZ_CP007687_3	3.1\|2632359\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632359-2632388	30	DQ003637	Listeria phage A500, complete genome	37232-37261	2	0.933
NZ_CP007687_3	3.1\|2632359\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632359-2632388	30	KJ094022	Listeria phage LP-030-3, complete genome	6787-6816	2	0.933
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	MH341451	Listeria phage PSU-VKH-LP019, complete genome	33369-33398	2	0.933
NZ_CP007687_3	3.10\|2632954\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632954-2632983	30	MH341452	Listeria phage PSU-VKH-LP040, complete genome	30076-30105	2	0.933
NZ_CP007687_3	3.10\|2632954\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632954-2632983	30	KP399677	Listeria phage vB_LmoS_188, complete genome	29411-29440	2	0.933
NZ_CP007687_3	3.10\|2632954\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632954-2632983	30	KP399678	Listeria phage vB_LmoS_293, complete genome	30647-30676	2	0.933
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	JB137888	Sequence 7 from Patent WO2012159774	3951-3980	3	0.9
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	JX442241	Listeria phage P70, complete genome	50802-50831	3	0.9
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NZ_CP011399	Listeria monocytogenes strain CFSAN008100 plasmid pCFSAN008100, complete sequence	64606-64635	4	0.867
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NC_021539	Listeria phage LP-030-2, complete genome	26551-26580	4	0.867
NZ_CP007687_3	3.10\|2632954\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632954-2632983	30	MH341451	Listeria phage PSU-VKH-LP019, complete genome	28454-28483	4	0.867
NZ_CP007687_3	3.10\|2632954\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632954-2632983	30	DQ003642	Listeria phage A006, complete genome	28892-28921	4	0.867
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	AJ312240	Bacteriophage PSA complete genome	26274-26303	5	0.833
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	MK448750	Streptococcus phage Javan393, complete genome	14096-14125	5	0.833
NZ_CP007687_3	3.8\|2632822\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632822-2632851	30	NZ_CP013332	Fusobacterium hwasookii ChDC F174 plasmid unnamed1, complete sequence	35394-35423	5	0.833
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	DQ003637	Listeria phage A500, complete genome	34063-34092	6	0.8
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KP399677	Listeria phage vB_LmoS_188, complete genome	33569-33598	6	0.8
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KJ094022	Listeria phage LP-030-3, complete genome	3092-3121	6	0.8
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KP399678	Listeria phage vB_LmoS_293, complete genome	35853-35882	6	0.8
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	CP025878	Escherichia coli strain 503458 plasmid p503458_84, complete sequence	24835-24864	6	0.8
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	NZ_CP025855	Escherichia coli strain 510016 plasmid p510016_84, complete sequence	27119-27148	6	0.8
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	CP025926	Escherichia coli strain 520873 plasmid p520873_84, complete sequence	73925-73954	6	0.8
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	CP025889	Escherichia coli strain 503046 plasmid p503046_85, complete sequence	51647-51676	6	0.8
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	HE962497	Streptococcus phage SP-QS1 complete genome	49933-49962	6	0.8
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	AP014318	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S32-C66, * SEQUENCING IN PROGRESS *	18568-18597	6	0.8
NZ_CP007687_3	3.1\|2632359\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632359-2632388	30	KT878766	Staphylococcus phage P1105, complete genome	32141-32170	7	0.767
NZ_CP007687_3	3.1\|2632359\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632359-2632388	30	NC_025460	Staphylococcus phage phiSa119, complete genome	7352-7381	7	0.767
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NC_027989	Campylobacter phage vB_CcoM-IBB_35 clone Contig1, complete genome	19442-19471	7	0.767
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KT898134	Aeromonas phage phiARM81mr, complete genome	20894-20923	7	0.767
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NC_042112	Campylobacter phage CP81, complete genome	57209-57238	7	0.767
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KF148616	Campylobacter phage CP8, complete genome	71096-71125	7	0.767
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NC_016562	Campylobacter phage CPX, complete genome	70863-70892	7	0.767
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	JX569801	Campylobacter phage CP30A, complete genome	118091-118120	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NC_015257	Tetragenococcus halophilus plasmid pHDC-I DNA, complete sequence	20068-20097	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NC_024991	Tetragenococcus halophilus plasmid pTDC-B DNA, complete sequence, strain: TyrB	531-560	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NC_010523	Tetragenococcus halophilus plasmid pHDC DNA, complete sequence	23529-23558	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NC_024990	Tetragenococcus halophilus plasmid pTDC-A DNA, complete sequence, strain: TyrA	531-560	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NZ_KX858825	Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence	3960-3989	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NC_016515	Enterobacter ludwigii strain EcWSU1 plasmid pEcWSU1_A, complete sequence	60920-60949	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NZ_CP035636	Enterobacter cloacae strain EN3600 plasmid unnamed4, complete sequence	32823-32852	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NZ_CP031569	Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence	110137-110166	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NC_018878	Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence	366315-366344	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NZ_CP009855	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-22e, complete sequence	81983-82012	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NZ_CP008907	Enterobacter hormaechei subsp. hoffmannii ECR091 plasmid pENT-4bd, complete sequence	39349-39378	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	MN842294	Leclercia adecarboxylata strain G426 plasmid pG426-FII, complete sequence	108724-108753	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NZ_CP026851	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0072 plasmid unnamed1	100353-100382	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NZ_CP029719	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence	39276-39305	7	0.767
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NZ_CP045770	Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence	43608-43637	7	0.767
NZ_CP007687_3	3.1\|2632359\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632359-2632388	30	JN638751	Bacillus phage G, complete genome	221970-221999	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NZ_CP050185	Bacillus thuringiensis strain HER1410 plasmid pLUSID2, complete sequence	94341-94370	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NC_021789	Cellulophaga phage phi19:3, complete genome	23831-23860	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NZ_CP037748	Campylobacter helveticus strain 2013D-9613 plasmid unnamed2, complete sequence	10327-10356	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	NZ_CP020480	Campylobacter helveticus strain ATCC 51209 plasmid pHELV-2, complete sequence	7615-7644	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	MK449012	Streptococcus phage Javan94, complete genome	10376-10405	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KF751797	Campylobacter phage CJIE4-5, complete genome	8480-8509	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KF751794	Campylobacter phage CJIE4-2, complete genome	6590-6619	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KF751795	Campylobacter phage CJIE4-3, complete genome	6557-6586	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KF751796	Campylobacter phage CJIE4-4, complete genome	6595-6624	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	MK448673	Streptococcus phage Javan119, complete genome	12281-12310	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	KF751793	Campylobacter phage CJIE4-1, complete genome	8033-8062	8	0.733
NZ_CP007687_3	3.2\|2632425\|30\|NZ_CP007687\|CRISPRCasFinder,CRT	2632425-2632454	30	MH107028	Campylobacter phage CP39, partial genome	13387-13416	9	0.7
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	NC_017296	Clostridium acetobutylicum EA 2018 plasmid pEA2018, complete sequence	181805-181834	9	0.7
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	NC_015686	Clostridium acetobutylicum DSM 1731 plasmid pSMBa, complete sequence	181805-181834	9	0.7
NZ_CP007687_3	3.4\|2632557\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2632557-2632586	30	NC_001988	Clostridium acetobutylicum ATCC 824 plasmid pSOL1, complete sequence	181805-181834	9	0.7
NZ_CP007687_3	3.11\|2633020\|30\|NZ_CP007687\|CRISPRCasFinder,CRT,PILER-CR	2633020-2633049	30	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	779867-779896	10	0.667
NZ_CP007687_2	2.6\|515789\|34\|NZ_CP007687\|PILER-CR,CRISPRCasFinder	515789-515822	34	NZ_CP032628	Lactococcus sp. 1JSPR-7 plasmid unnamed1, complete sequence	36527-36560	11	0.676

1. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to DQ003642 (Listeria phage A006, complete genome) position: , mismatch: 0, identity: 1.0

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
tcctgtttcatattttaaatatgtggatgc	Protospacer
******************************

2. spacer 2.4|515658|37|NZ_CP007687|PILER-CR,CRISPRCasFinder matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 1, identity: 0.973

agcgcaacaggtgccatatacaaactgcctttttttc	CRISPR spacer
agcgcaacaggggccatatacaaactgcctttttttc	Protospacer
*********** *************************

3. spacer 3.1|2632359|30|NZ_CP007687|CRISPRCasFinder,CRT matches to DQ003637 (Listeria phage A500, complete genome) position: , mismatch: 2, identity: 0.933

caagttaaagatatcaactacattcagaca	CRISPR spacer
caagttgaagatattaactacattcagaca	Protospacer
******.*******.***************

4. spacer 3.1|2632359|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KJ094022 (Listeria phage LP-030-3, complete genome) position: , mismatch: 2, identity: 0.933

caagttaaagatatcaactacattcagaca	CRISPR spacer
caagttgaagatattaactacattcagaca	Protospacer
******.*******.***************

5. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to MH341451 (Listeria phage PSU-VKH-LP019, complete genome) position: , mismatch: 2, identity: 0.933

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
agcctatatccccttcaaaaatcttcttgc	Protospacer
************************* ***.

6. spacer 3.10|2632954|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to MH341452 (Listeria phage PSU-VKH-LP040, complete genome) position: , mismatch: 2, identity: 0.933

cgatcactgacataaacgacacgaaaatca	CRISPR spacer
cgattacggacataaacgacacgaaaatca	Protospacer
****.** **********************

7. spacer 3.10|2632954|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to KP399677 (Listeria phage vB_LmoS_188, complete genome) position: , mismatch: 2, identity: 0.933

cgatcactgacataaacgacacgaaaatca	CRISPR spacer
cgattacagacataaacgacacgaaaatca	Protospacer
****.** **********************

8. spacer 3.10|2632954|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to KP399678 (Listeria phage vB_LmoS_293, complete genome) position: , mismatch: 2, identity: 0.933

cgatcactgacataaacgacacgaaaatca	CRISPR spacer
cgattacagacataaacgacacgaaaatca	Protospacer
****.** **********************

9. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to JB137888 (Sequence 7 from Patent WO2012159774) position: , mismatch: 3, identity: 0.9

tcttccattgtgataaactgataaactaaa	CRISPR spacer
tcttccattgtgatgaattgataaactaag	Protospacer
**************.**.***********.

10. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to JX442241 (Listeria phage P70, complete genome) position: , mismatch: 3, identity: 0.9

tcttccattgtgataaactgataaactaaa	CRISPR spacer
tcttccattgtgatgaattgataaactaag	Protospacer
**************.**.***********.

11. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NZ_CP011399 (Listeria monocytogenes strain CFSAN008100 plasmid pCFSAN008100, complete sequence) position: , mismatch: 4, identity: 0.867

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
cgactatatccccttcaaaaatcttcttgc	Protospacer
 * ********************** ***.

12. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 4, identity: 0.867

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
cgactatatccccttcaaaaatcttcttgc	Protospacer
 * ********************** ***.

13. spacer 3.10|2632954|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to MH341451 (Listeria phage PSU-VKH-LP019, complete genome) position: , mismatch: 4, identity: 0.867

cgatcactgacataaacgacacgaaaatca	CRISPR spacer
caattagcgacataaacgacacgaaaatca	Protospacer
*.**.* .**********************

14. spacer 3.10|2632954|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to DQ003642 (Listeria phage A006, complete genome) position: , mismatch: 4, identity: 0.867

cgatcactgacataaacgacacgaaaatca	CRISPR spacer
caattagcgacataaacgacacgaaaatca	Protospacer
*.**.* .**********************

15. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to AJ312240 (Bacteriophage PSA complete genome) position: , mismatch: 5, identity: 0.833

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ctactatatccccttcaaaaatcttcttgc	Protospacer
   ********************** ***.

16. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to MK448750 (Streptococcus phage Javan393, complete genome) position: , mismatch: 5, identity: 0.833

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
tgactatatcaccttcaaaaatctcattct	Protospacer
 * ******* *************.*** *

17. spacer 3.8|2632822|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013332 (Fusobacterium hwasookii ChDC F174 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.833

-tagacataaacagagagaaagcattaaata	CRISPR spacer
atggac-taaatagagaaaaagcattaaatt	Protospacer
 *.*** ****.*****.************

18. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to DQ003637 (Listeria phage A500, complete genome) position: , mismatch: 6, identity: 0.8

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ttactatatccccttcgaaaatcttcttgc	Protospacer
   *************.******** ***.

19. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KP399677 (Listeria phage vB_LmoS_188, complete genome) position: , mismatch: 6, identity: 0.8

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ctacaatatccccttcaaaaatcttcttgc	Protospacer
   * ******************** ***.

20. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KJ094022 (Listeria phage LP-030-3, complete genome) position: , mismatch: 6, identity: 0.8

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ctacaatatccccttcaaaaatcttcttgc	Protospacer
   * ******************** ***.

21. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KP399678 (Listeria phage vB_LmoS_293, complete genome) position: , mismatch: 6, identity: 0.8

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ctacaatatccccttcaaaaatcttcttgc	Protospacer
   * ******************** ***.

22. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to CP025878 (Escherichia coli strain 503458 plasmid p503458_84, complete sequence) position: , mismatch: 6, identity: 0.8

tcttccattgtgataaactgataaactaaa	CRISPR spacer
cttatcattatgataaaatgataaactaaa	Protospacer
..* .****.******* ************

23. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025855 (Escherichia coli strain 510016 plasmid p510016_84, complete sequence) position: , mismatch: 6, identity: 0.8

tcttccattgtgataaactgataaactaaa	CRISPR spacer
cttatcattatgataaaatgataaactaaa	Protospacer
..* .****.******* ************

24. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to CP025926 (Escherichia coli strain 520873 plasmid p520873_84, complete sequence) position: , mismatch: 6, identity: 0.8

tcttccattgtgataaactgataaactaaa	CRISPR spacer
cttatcattatgataaaatgataaactaaa	Protospacer
..* .****.******* ************

25. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to CP025889 (Escherichia coli strain 503046 plasmid p503046_85, complete sequence) position: , mismatch: 6, identity: 0.8

tcttccattgtgataaactgataaactaaa	CRISPR spacer
cttatcattatgataaaatgataaactaaa	Protospacer
..* .****.******* ************

26. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to HE962497 (Streptococcus phage SP-QS1 complete genome) position: , mismatch: 6, identity: 0.8

tcttccattgtgataaactgataaactaaa	CRISPR spacer
tcaatcattgtgataaattgataaacgtaa	Protospacer
**  .************.********  **

27. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to AP014318 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S32-C66, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
ttctgttttattttttaaatatgtgaacac	Protospacer
*.******.** *************.*..*

28. spacer 3.1|2632359|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KT878766 (Staphylococcus phage P1105, complete genome) position: , mismatch: 7, identity: 0.767

caagttaaagatatcaactacattcagaca	CRISPR spacer
caagttaaagatatgaacaacataccaatt	Protospacer
************** *** **** * .*.

29. spacer 3.1|2632359|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NC_025460 (Staphylococcus phage phiSa119, complete genome) position: , mismatch: 7, identity: 0.767

caagttaaagatatcaactacattcagaca	CRISPR spacer
caagttaaagatatgaacaacataccaatt	Protospacer
************** *** **** * .*.

30. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NC_027989 (Campylobacter phage vB_CcoM-IBB_35 clone Contig1, complete genome) position: , mismatch: 7, identity: 0.767

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ataaaatatccccttcataaatctttttgc	Protospacer
*    ************ ******* ***.

31. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KT898134 (Aeromonas phage phiARM81mr, complete genome) position: , mismatch: 7, identity: 0.767

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
agcctatctcgccttcaaaaatctcaacaa	Protospacer
******* ** *************.* ..

32. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NC_042112 (Campylobacter phage CP81, complete genome) position: , mismatch: 7, identity: 0.767

agcct---atatccccttcaaaaatcttattgt	CRISPR spacer
---ctaaaatatcaccttcaaaaatctttttac	Protospacer
   **   ***** ************** **..

33. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KF148616 (Campylobacter phage CP8, complete genome) position: , mismatch: 7, identity: 0.767

agcct---atatccccttcaaaaatcttattgt	CRISPR spacer
---ctaaaatatcaccttcaaaaatctttttac	Protospacer
   **   ***** ************** **..

34. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NC_016562 (Campylobacter phage CPX, complete genome) position: , mismatch: 7, identity: 0.767

agcct---atatccccttcaaaaatcttattgt	CRISPR spacer
---ctaaaatatcaccttcaaaaatctttttac	Protospacer
   **   ***** ************** **..

35. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to JX569801 (Campylobacter phage CP30A, complete genome) position: , mismatch: 7, identity: 0.767

agcct---atatccccttcaaaaatcttattgt	CRISPR spacer
---ctaaaatatcaccttcaaaaatctttttac	Protospacer
   **   ***** ************** **..

36. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_015257 (Tetragenococcus halophilus plasmid pHDC-I DNA, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
tcaaaattcatattttaaatatggggatca	Protospacer
**  . ***************** ****

37. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_024991 (Tetragenococcus halophilus plasmid pTDC-B DNA, complete sequence, strain: TyrB) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
tcaaaattcatattttaaatatggggatca	Protospacer
**  . ***************** ****

38. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_010523 (Tetragenococcus halophilus plasmid pHDC DNA, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
tcaaaattcatattttaaatatggggatca	Protospacer
**  . ***************** ****

39. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_024990 (Tetragenococcus halophilus plasmid pTDC-A DNA, complete sequence, strain: TyrA) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
tcaaaattcatattttaaatatggggatca	Protospacer
**  . ***************** ****

40. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX858825 (Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

41. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_016515 (Enterobacter ludwigii strain EcWSU1 plasmid pEcWSU1_A, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

42. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035636 (Enterobacter cloacae strain EN3600 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

43. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031569 (Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

44. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_018878 (Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
accatcttcatattttaaatatgtagacgt	Protospacer
 **  .******************.**.*.

45. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009855 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-22e, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

46. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP008907 (Enterobacter hormaechei subsp. hoffmannii ECR091 plasmid pENT-4bd, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

47. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to MN842294 (Leclercia adecarboxylata strain G426 plasmid pG426-FII, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtatac	Protospacer
 *   ***************** ** **.*

48. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026851 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0072 plasmid unnamed1) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

49. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029719 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

50. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045770 (Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence) position: , mismatch: 7, identity: 0.767

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
acgattttcatattttaaatatctgtattc	Protospacer
 *   ***************** ** ** *

51. spacer 3.1|2632359|30|NZ_CP007687|CRISPRCasFinder,CRT matches to JN638751 (Bacillus phage G, complete genome) position: , mismatch: 8, identity: 0.733

caagttaaagatatcaactacattcagaca	CRISPR spacer
aaagttaaaggtatcaactacaaggattta	Protospacer
 *********.***********   *  .*

52. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NZ_CP050185 (Bacillus thuringiensis strain HER1410 plasmid pLUSID2, complete sequence) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
gtaacttatccccttcaaaaatcgcattgt	Protospacer
.   . ***************** .*****

53. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NC_021789 (Cellulophaga phage phi19:3, complete genome) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ttagtatatccccttcataaatctcattcc	Protospacer
    ************* ******.*** .

54. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NZ_CP037748 (Campylobacter helveticus strain 2013D-9613 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ttacaatatcccctgcataaatcttatttc	Protospacer
   * ********* ** ********** .

55. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to NZ_CP020480 (Campylobacter helveticus strain ATCC 51209 plasmid pHELV-2, complete sequence) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ttacaatatcccctgcataaatcttatttc	Protospacer
   * ********* ** ********** .

56. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ttacaatatccccatcaaaaatcttaacgc	Protospacer
   * ******** ************ .*.

57. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KF751797 (Campylobacter phage CJIE4-5, complete genome) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ataaaatatctccttcataaatcttatttc	Protospacer
*    *****.****** ********** .

58. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KF751794 (Campylobacter phage CJIE4-2, complete genome) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ataaaatatctccttcataaatcttatttc	Protospacer
*    *****.****** ********** .

59. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KF751795 (Campylobacter phage CJIE4-3, complete genome) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ataaaatatctccttcataaatcttatttc	Protospacer
*    *****.****** ********** .

60. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KF751796 (Campylobacter phage CJIE4-4, complete genome) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ataaaatatctccttcataaatcttatttc	Protospacer
*    *****.****** ********** .

61. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ttacaatatccccatcaaaaatcttaacgc	Protospacer
   * ******** ************ .*.

62. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to KF751793 (Campylobacter phage CJIE4-1, complete genome) position: , mismatch: 8, identity: 0.733

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
ataaaatatctccttcataaatcttatttc	Protospacer
*    *****.****** ********** .

63. spacer 3.2|2632425|30|NZ_CP007687|CRISPRCasFinder,CRT matches to MH107028 (Campylobacter phage CP39, partial genome) position: , mismatch: 9, identity: 0.7

agcctatatccccttcaaaaatcttattgt	CRISPR spacer
taataatatccccttcataaatcttttttc	Protospacer
 . . ************ ******* ** .

64. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_017296 (Clostridium acetobutylicum EA 2018 plasmid pEA2018, complete sequence) position: , mismatch: 9, identity: 0.7

tcttccattgtgataaactgataaactaaa	CRISPR spacer
acttccattgtaataaactgatatttgttt	Protospacer
 **********.***********  .

65. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_015686 (Clostridium acetobutylicum DSM 1731 plasmid pSMBa, complete sequence) position: , mismatch: 9, identity: 0.7

tcttccattgtgataaactgataaactaaa	CRISPR spacer
acttccattgtaataaactgatatttgttt	Protospacer
 **********.***********  .

66. spacer 3.4|2632557|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_001988 (Clostridium acetobutylicum ATCC 824 plasmid pSOL1, complete sequence) position: , mismatch: 9, identity: 0.7

tcttccattgtgataaactgataaactaaa	CRISPR spacer
acttccattgtaataaactgatatttgttt	Protospacer
 **********.***********  .

67. spacer 3.11|2633020|30|NZ_CP007687|CRISPRCasFinder,CRT,PILER-CR matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 10, identity: 0.667

tcctgtttcatattttaaatatgtggatgc	CRISPR spacer
cagaaacatatatattaaatatgtggatgc	Protospacer
.   . . .**** ****************

68. spacer 2.6|515789|34|NZ_CP007687|PILER-CR,CRISPRCasFinder matches to NZ_CP032628 (Lactococcus sp. 1JSPR-7 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.676

gttggtaggtttaaccaaagatgatcaccatgtc	CRISPR spacer
cttagtacgtttaaccaaagatgatgatggaaag	Protospacer
 **.*** ***************** *. . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

118394 : 124919

Listeria_phage(33.33%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721739.1\|118394_118847_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
WP_003721740.1\|118852_119188_-	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003732219.1\|119404_119833_+	hypothetical protein	NA	NA	NA	NA
WP_014931069.1\|119844_120261_+	hypothetical protein	A8ASQ1	Listeria_phage	7.7e-21	39.3
WP_009930418.1\|120538_120928_+	DUF5072 family protein	NA	NA	NA	NA
WP_003721744.1\|120940_121453_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003740132.1\|121500_121803_+	hypothetical protein	NA	NA	NA	NA
WP_072217178.1\|121844_122249_+	phenylalanine racemase	NA	NA	NA	NA
WP_031665466.1\|122235_124104_+	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
WP_009911828.1\|124100_124919_+\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	7.2e-39	35.0

DBSCAN-SWA_2

1094274 : 1101697

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721506.1\|1094274_1094658_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
WP_026749861.1\|1094679_1095663_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	4.1e-12	34.6
WP_026749862.1\|1095677_1096691_+	glycosyltransferase	A0A1V0SAH6	Catovirus	7.9e-11	32.0
WP_003721509.1\|1096899_1098390_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
WP_003727000.1\|1098401_1099226_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	9.7e-68	52.6
WP_023549061.1\|1099238_1099547_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003732712.1\|1099607_1100012_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_020246560.1\|1100140_1101697_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.3e-17	28.1

DBSCAN-SWA_3

1190830 : 1296579

118

Listeria_phage(70.59%)

holin,integrase,tail,protease,terminase,tRNA,portal,capsid

attL 1196218:1196235|attR 1260750:1260767

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033920336.1\|1190830_1193239_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_014600776.1\|1193399_1194101_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-33	35.4
WP_026749899.1\|1194114_1197525_+	FtsX-like permease family protein	NA	NA	NA	NA
1196218:1196235	attL	NA	NA	NA	NA
WP_003721623.1\|1197622_1198075_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_033920334.1\|1198090_1201291_+	MMPL family transporter	NA	NA	NA	NA
WP_003732773.1\|1201397_1202072_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	7.5e-50	47.7
WP_072215733.1\|1202108_1203035_-	ribonuclease HIII	NA	NA	NA	NA
WP_003740576.1\|1203188_1203452_+	cell division protein ZapA	NA	NA	NA	NA
WP_003723849.1\|1203451_1203994_+	CvpA family protein	NA	NA	NA	NA
WP_033920332.1\|1204086_1205799_+	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	5.1e-18	24.8
WP_003732776.1\|1205821_1208179_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.0e-21	50.4
WP_008947590.1\|1208259_1208571_+	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	1.2e-18	38.6
WP_033920329.1\|1208646_1210458_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_003732778.1\|1210646_1211861_+	aspartate kinase	NA	NA	NA	NA
WP_003733801.1\|1211916_1212411_-	YslB family protein	NA	NA	NA	NA
WP_003723856.1\|1212558_1213359_+	glutamate racemase	NA	NA	NA	NA
WP_003732780.1\|1213371_1214118_+	ribonuclease PH	NA	NA	NA	NA
WP_014600781.1\|1214121_1214733_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_015454643.1\|1214769_1215294_+	metallophosphoesterase	NA	NA	NA	NA
WP_026749902.1\|1215579_1216734_-\|integrase	site-specific integrase	A8ATC7	Listeria_phage	4.1e-213	97.1
WP_012951517.1\|1216877_1217534_-	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_026749903.1\|1217585_1218038_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	8.5e-82	96.0
WP_026749904.1\|1218054_1218378_-	helix-turn-helix transcriptional regulator	A0A059T6G1	Listeria_phage	8.5e-36	71.0
WP_009929535.1\|1219182_1219506_+	hypothetical protein	NA	NA	NA	NA
WP_009929536.1\|1219520_1219724_+	helix-turn-helix transcriptional regulator	A0A059T5F8	Listeria_phage	3.1e-28	100.0
WP_015987310.1\|1219725_1219968_+	hypothetical protein	A8ATD2	Listeria_phage	1.4e-43	100.0
WP_009929539.1\|1219970_1220156_+	hypothetical protein	A0A059T7Z3	Listeria_phage	1.7e-28	96.7
WP_009931096.1\|1220390_1220543_+	hypothetical protein	A0A059T7S2	Listeria_phage	3.4e-19	98.0
WP_026749905.1\|1220679_1220934_+	hypothetical protein	A0A059T6G3	Listeria_phage	4.3e-35	91.5
WP_031664911.1\|1220951_1221929_+	DNA cytosine methyltransferase	H7BVD3	unidentified_phage	9.2e-49	37.5
WP_031664910.1\|1221925_1222519_+	DUF1642 domain-containing protein	A8ATD8	Listeria_phage	3.1e-60	61.7
WP_031664908.1\|1222521_1222965_+	hypothetical protein	NA	NA	NA	NA
WP_014929526.1\|1222961_1223108_+	hypothetical protein	A8ATZ0	Listeria_phage	1.7e-20	100.0
WP_031664906.1\|1223345_1223879_+	pentapeptide repeat-containing protein	A0A060AFJ6	Listeria_phage	2.2e-44	85.2
WP_031664904.1\|1223982_1224198_+	hypothetical protein	NA	NA	NA	NA
WP_003731703.1\|1224194_1224371_+	hypothetical protein	A0A076G7F4	Listeria_phage	1.9e-21	87.9
WP_014930899.1\|1224760_1224988_+	DUF3850 domain-containing protein	A0A059T7N3	Listeria_phage	4.6e-28	84.0
WP_031664899.1\|1225304_1225520_+	hypothetical protein	A0A059T7T1	Listeria_phage	2.8e-27	93.7
WP_031664897.1\|1225569_1226130_-	hypothetical protein	NA	NA	NA	NA
WP_009933642.1\|1226233_1226407_+	hypothetical protein	A0A059T5G3	Listeria_phage	5.2e-24	100.0
WP_014929534.1\|1226403_1226787_+	hypothetical protein	A0A059T6A2	Listeria_phage	5.5e-66	99.2
WP_033920325.1\|1226788_1227268_+	siphovirus Gp157 family protein	A0A059T803	Listeria_phage	1.2e-78	98.7
WP_003743935.1\|1227280_1227970_+	AAA family ATPase	A0A059T7T3	Listeria_phage	2.6e-130	100.0
WP_026749915.1\|1228033_1229290_+	DEAD/DEAH box helicase	Q8W5V9	Listeria_phage	5.4e-219	90.0
WP_026749916.1\|1229313_1229811_+	DUF669 domain-containing protein	A0A059T5G4	Listeria_phage	3.2e-50	57.3
WP_026749917.1\|1229830_1232104_+	DNA primase	R4IBW2	Listeria_phage	0.0e+00	74.3
WP_031664889.1\|1232244_1232565_+	VRR-NUC domain-containing protein	Q8W5V6	Listeria_phage	1.2e-53	97.2
WP_033920321.1\|1232561_1232831_+	hypothetical protein	W0GBM0	Listeria_phage	3.1e-15	72.2
WP_031664887.1\|1232941_1233472_+	DUF3310 domain-containing protein	A0A059T7T5	Listeria_phage	1.3e-73	77.3
WP_031664885.1\|1233472_1233898_+	DUF722 domain-containing protein	A0A059T6H4	Listeria_phage	1.8e-73	99.3
WP_031664882.1\|1234124_1235066_+	DUF4868 domain-containing protein	A0A1Q1PW39	Staphylococcus_phage	5.9e-45	33.0
WP_031664880.1\|1235091_1235703_+	hypothetical protein	A0A1Q1PW40	Staphylococcus_phage	6.0e-22	42.8
WP_031664879.1\|1235732_1236059_+	hypothetical protein	A0A059T5G5	Listeria_phage	9.5e-51	93.5
WP_031664877.1\|1236058_1236373_+	HNH endonuclease	A8ATF8	Listeria_phage	3.2e-56	97.1
WP_012951543.1\|1236421_1236778_+\|terminase	P27 family phage terminase small subunit	A0A059T7Y1	Listeria_phage	2.0e-46	98.0
WP_026749921.1\|1236774_1238418_+\|terminase	terminase large subunit	A0A059T7Q8	Listeria_phage	0.0e+00	99.6
WP_009917707.1\|1238427_1238817_-	DUF2513 domain-containing protein	A0A1Q1PVT8	Staphylococcus_phage	3.7e-17	39.8
WP_026749922.1\|1238867_1239998_+\|portal	phage portal protein	A0A059T6F0	Listeria_phage	6.1e-214	99.2
WP_026749923.1\|1239994_1240792_+\|protease	Clp protease ClpP	A0A059T5F2	Listeria_phage	6.2e-144	99.6
WP_014930913.1\|1240818_1241970_+\|capsid	phage major capsid protein	A0A059T678	Listeria_phage	6.3e-214	100.0
WP_167620291.1\|1241976_1242147_+	hypothetical protein	A0A059T7Y2	Listeria_phage	2.4e-21	98.2
WP_014930914.1\|1242156_1242456_+	hypothetical protein	A0A059T7R0	Listeria_phage	5.3e-48	100.0
WP_025370587.1\|1242439_1242805_+	hypothetical protein	A0A059T6F2	Listeria_phage	2.4e-63	99.2
WP_026747164.1\|1242801_1243203_+	hypothetical protein	A8ATA2	Listeria_phage	5.2e-67	97.0
WP_026749924.1\|1243199_1243583_+	hypothetical protein	A0A059T681	Listeria_phage	2.1e-65	96.9
WP_025370590.1\|1243603_1244191_+\|tail	phage tail protein	A0A059T7Y4	Listeria_phage	1.3e-106	99.0
WP_025370591.1\|1244261_1244594_+	hypothetical protein	A0A059T7R2	Listeria_phage	8.7e-52	97.3
WP_009931626.1\|1244644_1244806_+	hypothetical protein	A0A059T6F4	Listeria_phage	4.3e-20	98.0
WP_026749925.1\|1244809_1249720_+\|tail	phage tail tape measure protein	A0A059T5F4	Listeria_phage	0.0e+00	96.0
WP_026749926.1\|1249716_1251366_+\|tail	phage tail family protein	A0A059T682	Listeria_phage	0.0e+00	99.3
WP_026749927.1\|1251378_1253673_+\|tail	phage tail protein	A0A059T7Y6	Listeria_phage	0.0e+00	99.2
WP_026749928.1\|1253662_1254757_+	hypothetical protein	A0A059T7R4	Listeria_phage	1.9e-175	84.9
WP_003733957.1\|1254807_1255113_+	hypothetical protein	A0A059T5E6	Listeria_phage	1.8e-43	100.0
WP_014929558.1\|1255112_1255394_+\|holin	phage holin	A8ATW3	Listeria_phage	6.7e-45	98.9
WP_077914485.1\|1255390_1256245_+	N-acetylmuramoyl-L-alanine amidase	P89923	Bacillus_phage	8.1e-33	50.6
WP_026749929.1\|1256849_1257359_+	hypothetical protein	NA	NA	NA	NA
WP_026749930.1\|1257754_1257940_-	hypothetical protein	A0A059T7Z0	Listeria_phage	5.4e-19	89.7
WP_031664868.1\|1258380_1258614_+	hypothetical protein	A8ATC5	Listeria_phage	1.1e-32	89.6
WP_003729706.1\|1260661_1261255_-	YdeI/OmpD-associated family protein	NA	NA	NA	NA
1260750:1260767	attR	NA	NA	NA	NA
WP_012581425.1\|1261391_1261799_-	VOC family protein	NA	NA	NA	NA
WP_009924169.1\|1261963_1262563_+	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	5.8e-30	41.0
WP_003723543.1\|1262594_1262855_-	hypothetical protein	NA	NA	NA	NA
WP_010989717.1\|1262978_1264391_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	8.3e-51	31.8
WP_003723545.1\|1264415_1264679_+	DUF3116 family protein	NA	NA	NA	NA
WP_003723546.1\|1264846_1265323_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_003723547.1\|1265360_1265606_-	hypothetical protein	NA	NA	NA	NA
WP_033920317.1\|1265602_1266808_-	MFS transporter	NA	NA	NA	NA
WP_003723549.1\|1267012_1267672_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003723550.1\|1267713_1267908_-	hypothetical protein	NA	NA	NA	NA
WP_003723551.1\|1267974_1268823_-	YitT family protein	NA	NA	NA	NA
WP_003723553.1\|1269153_1269291_-	hypothetical protein	NA	NA	NA	NA
WP_009931701.1\|1269441_1270155_+	trehalose operon repressor	NA	NA	NA	NA
WP_033920315.1\|1270185_1271832_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_023552381.1\|1271850_1273335_-	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_014601949.1\|1273451_1273913_+	NUDIX hydrolase	NA	NA	NA	NA
WP_003726717.1\|1273951_1274416_-	hypothetical protein	NA	NA	NA	NA
WP_014601950.1\|1274604_1275519_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_014601951.1\|1275543_1276791_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	4.2e-107	52.0
WP_014601952.1\|1276774_1277605_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-45	42.0
WP_031671806.1\|1277752_1278892_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_003723563.1\|1278972_1279368_-	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003727524.1\|1279518_1279734_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010989719.1\|1279852_1280386_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003732795.1\|1280403_1281069_+	hypothetical protein	NA	NA	NA	NA
WP_003732796.1\|1281330_1282269_+	hypothetical protein	NA	NA	NA	NA
WP_003723884.1\|1282383_1283667_+	trigger factor	NA	NA	NA	NA
WP_033920310.1\|1283852_1285112_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	6.1e-146	63.4
WP_003723887.1\|1285230_1285797_+	type I signal peptidase SipX	NA	NA	NA	NA
WP_009924619.1\|1285831_1286401_+	type I signal peptidase SipY	NA	NA	NA	NA
WP_003723889.1\|1286502_1287045_+	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003723890.1\|1287054_1287918_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003723891.1\|1287914_1288700_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.0e-26	39.2
WP_003723892.1\|1288833_1289694_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_009924617.1\|1289965_1292044_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	1.4e-107	37.7
WP_033920307.1\|1292106_1293411_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_009911635.1\|1293693_1294596_+	tyrosine recombinase XerC	A0A097EYL9	Mycobacterium_phage	1.2e-13	28.6
WP_003724001.1\|1294616_1295156_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_031645070.1\|1295169_1296579_+\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	1.7e-43	27.8

DBSCAN-SWA_4

1828213 : 1836499

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033921148.1\|1828213_1828780_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.0e-25	35.9
WP_031665593.1\|1828776_1829826_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	9.2e-63	44.4
WP_003722245.1\|1829844_1831272_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_033921146.1\|1831256_1833476_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-159	41.2
WP_033921144.1\|1833468_1834152_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|1834155_1834401_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_010989809.1\|1834412_1835126_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.3e-41	38.3
WP_003729814.1\|1835206_1836499_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_5

2495373 : 2503217

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722604.1\|2495373_2496345_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
WP_003722605.1\|2496352_2497321_-	YvcK family protein	A1IMD5	Streptococcus_phage	6.7e-68	43.3
WP_010990001.1\|2497322_2498198_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-08	29.7
WP_012952017.1\|2498305_2500036_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	3.0e-175	54.0
WP_077421975.1\|2500077_2501139_-	galactose mutarotase	NA	NA	NA	NA
WP_014601137.1\|2501155_2502139_-	UDP-glucose 4-epimerase GalE	A0A1V0SG19	Hokovirus	1.6e-48	37.2
WP_003722610.1\|2502257_2503217_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007687

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection