CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP011504	Burkholderia pyrrocinia strain DSM 10685 chromosome 2, complete sequence	2 crisprs	csa3,Cas14u_CAS-V,cas14j,cas3,DinG	2	2	1
NZ_CP011505	Burkholderia pyrrocinia strain DSM 10685 chromosome 3, complete sequence	0 crisprs	WYL,RT	0	0	1
NZ_CP011503	Burkholderia pyrrocinia strain DSM 10685 chromosome 1, complete sequence	0 crisprs	WYL,csa3,cas3,DEDDh,DinG	0	0	4
NZ_CP011506	Burkholderia pyrrocinia strain DSM 10685 plasmid p2327, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011504_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011504_1

869435-869640

Orphan

Consensus_repeat	Method
GACCCGGCGTTGTCGCCGACGAGGCCACCCGCCGTGGC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP011504_1

>merge|NZ_CP011504|1|869435-869640|PILER-CR
GAACCGCCGTTCTCGCCGACGAGGCCGCCCGCGGTGCTCGATGCGCCGGCGACAACCGACCCACGCGCATCGGACGACTTCGCGCTCCCGGTGTTGACGCCGACCAGGCCACCCGCCTTGGCGTTGTCGCCCACGGTCACGCTGCCCGTCGCGTCGGAGGCTTCGATCGACGCGGCGTTGTAGCCGACGAGGCCACCCGCCGTCGC

>NZ_CP011504|1|1|869435-869640|PILER-CR
GAACCGCCGTTCTCGCCGACGAGGCCGCCCGCGGTGCT	CGATGCGCCGGCGACAACCGACCCACGCGCATCGGACGACTTCGCG
CTCCCGGTGTTGACGCCGACCAGGCCACCCGCCTTGGC	GTTGTCGCCCACGGTCACGCTGCCCGTCGCGTCGGAGGCTTCGATC
GACGCGGCGTTGTAGCCGACGAGGCCACCCGCCGTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011504.1\|WP_082146268.1\|853154_854099_+\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP011504.1\|WP_047901892.1\|878411_879110_-\|YebB-family-permuted-papain-like-enzyme	unknown	unknown	gnl\|CDD\|183152
NZ_CP011504.1\|WP_047901895.1\|881849_882629_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP011504.1\|WP_047903674.1\|875313_876951_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP011504.1\|WP_047901881.1\|855046_855640_+\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_CP011504.1\|WP_047901889.1\|872160_875250_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|214908
NZ_CP011504.1\|WP_158361631.1\|859222_860239_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_CP011504.1\|WP_006749370.1\|880052_880511_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP011504.1\|WP_047901890.1\|877381_878014_+\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NZ_CP011504.1\|WP_047901883.1\|856532_859040_+\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|225729
NZ_CP011504.1\|WP_047901891.1\|878044_878332_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP011504.1\|WP_148669121.1\|854190_854517_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011504.1\|WP_047901885.1\|863861_864521_-\|response-regulator	unknown	unknown	gnl\|CDD\|182771
NZ_CP011504.1\|WP_047901882.1\|855693_856410_+\|molecular-chaperone	unknown	unknown	gnl\|CDD\|225663
NZ_CP011504.1\|WP_047901893.1\|880636_881371_+\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215
NZ_CP011504.1\|WP_047901887.1\|865141_868246_-\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|182772
NZ_CP011504.1\|WP_047901877.1\|850937_851465_-\|CS1-type-fimbrial-major-subunit	unknown	unknown	gnl\|CDD\|367947
NZ_CP011504.1\|WP_047901884.1\|860575_863674_-\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP011504.1\|WP_047903675.1\|879262_879832_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011504.1\|WP_047901894.1\|881363_881672_+\|AzlD-family-protein	unknown	unknown	gnl\|CDD\|226916

Protein	Function_ID	Function_description	E-value
NZ_CP011504.1\|WP_082146268.1\|853154_854099_+\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	1.62366e-13
NZ_CP011504.1\|WP_047901892.1\|878411_879110_-\|YebB-family-permuted-papain-like-enzyme	gnl\|CDD\|183152	PRK11470, PRK11470, YebB family permuted papain-like enzyme.	1.1507e-117
NZ_CP011504.1\|WP_047901895.1\|881849_882629_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.71313e-100
NZ_CP011504.1\|WP_047901881.1\|855046_855640_+\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	1.31881e-18
NZ_CP011504.1\|WP_047903674.1\|875313_876951_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	2.87816e-102
NZ_CP011504.1\|WP_047901889.1\|872160_875250_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|214908	smart00912, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	1.55505e-22
NZ_CP011504.1\|WP_158361631.1\|859222_860239_+\|fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	4.69969e-13
NZ_CP011504.1\|WP_006749370.1\|880052_880511_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	6.00699e-53
NZ_CP011504.1\|WP_047901890.1\|877381_878014_+\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	1.92276e-45
NZ_CP011504.1\|WP_047901883.1\|856532_859040_+\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|225729	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP011504.1\|WP_047901891.1\|878044_878332_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.46323e-09
NZ_CP011504.1\|WP_047901885.1\|863861_864521_-\|response-regulator	gnl\|CDD\|182771	PRK10840, PRK10840, transcriptional regulator RcsB; Provisional.	1.67785e-46
NZ_CP011504.1\|WP_047901882.1\|855693_856410_+\|molecular-chaperone	gnl\|CDD\|225663	COG3121, FimC, P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion].	5.93259e-76
NZ_CP011504.1\|WP_047901893.1\|880636_881371_+\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	1.81939e-65
NZ_CP011504.1\|WP_047901887.1\|865141_868246_-\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|182772	PRK10841, PRK10841, two-component system sensor histidine kinase RcsC.	4.27737e-73
NZ_CP011504.1\|WP_047901877.1\|850937_851465_-\|CS1-type-fimbrial-major-subunit	gnl\|CDD\|367947	pfam04449, Fimbrial_CS1, CS1 type fimbrial major subunit. Fimbriae, also known as pili, form filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometres. They enable the cell to colonise host epithelia. This family constitutes the major subunits of CS1 like pili, including CS2 and CFA1 from Escherichia coli, and also the Cable type II pilin major subunit from Burkholderia cepacia. The major subunit of CS1 pili is called CooA. Periplasmic CooA is mostly complexed with the assembly protein CooB. In addition, a small pool of CooA multimers, and CooA-CooD complexes exists, but the functional significance is unknown. A member of this family has also been identified in Salmonella typhi and Salmonella enterica.	0.00733285
NZ_CP011504.1\|WP_047901884.1\|860575_863674_-\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	2.83253e-82
NZ_CP011504.1\|WP_047901894.1\|881363_881672_+\|AzlD-family-protein	gnl\|CDD\|226916	COG4541, COG4541, Predicted membrane protein [Function unknown].	2.02499e-28

>NZ_CP011504.1|WP_047901887.1|865141_868246_-|hybrid-sensor-histidine-kinase/response-regulator
MPQSPLQSLRRYQSISVFGGGIVVTVLVLIACGLGMASIVSGYVEGARRNYLNGLEQTLNEIQVSETSFRNGVANAQLIWQEASGAPAAVVDEFLLNDQRVATRPHPSLVVGVPAQTGNRAEVARYLSLSVLLARICAASSINRGRTLEGYHYSTRTGLFALIPHRDRDDPALVSPESRARVLDALRVDFERPYPGIVDARPHVRWLAPFIDPVSGQSRIRIAAEARDNGKPFAVLVTEYPPEYLLSWLADYRPEGAFYITTADGRLVTMDPSAGDADRVESLLKLNPSRGGASSSGAPVFRDGFLLFHGKLEPTGWTLAYALSWTDIAAGVARSAGTLGAATLLALMVMWGLLLRFHRREFVPLYAHSQRVFDSEALCRSVIEMAPIGLGLIAREDGRFMLVSPALTDMVDRIGGDYHALSSQVADAWQARGDAGGVPHDELLLGGVEAAHLHLEFVACGARYQGTDVLIAAVADMTAKRQLVQQLEEAVRAADSANAAKSSFLAAMSHEIRTPLNVILGNLELLERSALDAVQHDRVHTLRTSATSLLALVSDILDFSKIEAGAMSVESIEFDVIATVERELNAFATIAKAKGVQLFCEIRASSTQQMRGDPTRFAQVLRNLLSNALKFTDVGRVTVRVAVVAERHDTPELSVEVEDTGIGIAAEHRHKLFKAFSQVDTSITRRYGGTGLGLALCSRLVAAMGGRLAVDSKPGAGSRFMVLLPLGMNVVALDRPRAARAHALTLIAAHPAWRDFALPHLHAWGLDVSVYDSPSSLPGGVVRRGAVVLFGDSDTWSHADLASLSDCELLILAIPDGPLEPYRAGDTVRVSSYSLGGLRAALALGGPMGDESGFDVVSGDDPRRDDSHARDSATVEMSRAAAKHGSRALRVLVADDETINGSIFSEQLTALGCTAAECGSGRAALESLAGGDWDVLLIGDDLPDMRAHQLAEAAHGVDPACDVLVVTSHLTPEGMHRCAAAGVRRVLTKPVTLGHLRGALAHAWQRRAATSAKEPCAAACPSGSTNHETTLHDK
>NZ_CP011504.1|WP_047901885.1|863861_864521_-|response-regulator
MDEFFVRVMVADDHPASALGMSQSLQGNSTIKLVGTVSNSTDLVAALDAQQSDVLVLDYVMPGGKYGDGLVLLSFLQRRYPALHIVTITMIDNPSVLRAIHKQGVSCILSKSDAISHLIGAVHAAYVGANYMSPYIKQLLQDIESEPVARALTTREIEVVRLFGAGYTVGEIAAQLHRSKQTISSQKSSAMKKLGIVRDADLIRYNDEQKLAGASDDEA
>NZ_CP011504.1|WP_047901884.1|860575_863674_-|hybrid-sensor-histidine-kinase/response-regulator
MPAKLKRLVSHATVAVRKPFEPGRVRRQQQFLLYGSGVAISVFILVCATLVLLLDVQESLERFRVEFTGRRAELVAEVEIMRALRNRYVEDMELQWASVAEDSPGLPGLLAGKHGKQTFVGRKGRIAIAAFADIPPAASANSRLPYLARYLDGVEVTGVLPPPQPADPGGSAYLIDPNGDFIVAAGHPLVKRALALPAGFDVRALVEQLLPTTNDTAVSTADAAVSTAPAVRRNAIALDRRFDPVLGRSVLRMVQWVRGANGRPVVWFVINSLPLIEGILRSPGAGREYALVDSGGNLLLGGQPDSAMVSRALEHARHDAGERAAAHRVGMNFVVSDRVPRSDEVVMATISWRAVLSDVALRASLTVAPALFAIALLWIAIVMFDRRALRPANRRAIRLIESEALNRTLIRTAPAGLVLLSFADGEAIVRNDAMIAYERDVEGEPLGKRLWHAYRDDTPAGNARKRVTRELAVERAGYGTVYLDAHIARTKYRGIDVLLCTLLDITARKQAEEKLREAREAAELANKAKSTFLATMSHEIRTPLNAIIGNLELMERAQMAAPLRRRLGTIMSSSDALLRVINDVLDLSKAESNQMALESIPFDLHRVVNDVAAIFRPLADAKNLTLACRIAPDLADGYVGDSTRLRQLVSNLVSNAIKFTKRGGVTIDVRLAQAGAAGRGVEIAVSDTGIGIPEDSMPTLFDVYIQTDASIYRRFGGTGLGLPLCRRIVTLMGGELSVDSRLGEGTVFVAALPLPEAPAGWRDDAPEPGAFEGTARTYEAEAASEVGAETDAHAEADDEEPLQVLVAEDHPASRALLRDQLDALGYDATIVSNGIEAMRAFFERPYDVVLTDLGMPELDGFALANFLREQGARVPVIAMTAHATDEDRRRCEQAGAVEVVLKPLSIETLDAALRRHAGRNTVSSAPGQPPIALAMTDEVRRALRDATLNSLAAIGDALASGDADTLRIELHSMRGGFALAGDVEARDACARAEHAMRDGGPEALERIWHSIEDAVRLALGRLSTDDEPGSRV
>NZ_CP011504.1|WP_158361631.1|859222_860239_+|fimbrial-protein
MLLTAFESAHACQMLFWAGIIRPSVPATITSARDSGQPGTLIGPGAIANERGMSLFQCSLSGKVGKVGVKAMGTLVPNVTYDSEGKSFPVYETGVPGIGFALMAVPLSDHSVVGADWKAVRPEETLVSDRESQITYFYYVRYQAALVFTGSLATGTYTIPQRRVATTTAYAPNGAVAFSAITDLGAMTIKVTASGCTLTSGAQTNVKLPQLVGNKLKAVGAVSDESAPVTLRVNCQGAVNVYTTLTDAANPANEGTILSAHPGSTSRGVGLQIYKQGSETPLHFGPDSAVKGNTNQWLAGQVTDGSLSIPLVARYVKTAQTFTPGSLDASATFTFSYQ
>NZ_CP011504.1|WP_047901883.1|856532_859040_+|fimbrial-biogenesis-outer-membrane-usher-protein
MENVRKEVDIWTAAQIGAPCLALLGLVLPAQGHAVEFNESFLRKGEGPVELSYFEKGSSVLPGSYDVDVYLNHTLVKRQDVVFRADADGAVKPAVTLGLLRTAGVNVARLEKDGRIAAGADDTTIVDLPAVADGAAVEFEANTLSLNISFPQLYVSRTSRGYVDQSLWDDGMPALYSDYQVSYSRNDSHGHNNEYYFVGLRNGFNAGGWRFRNESTLTGTTGAGSRFTSNRTYVERDIRRLRSKVAAGELYTSGDIFDSVRFVGAQIGTDLGMLPDSEVGFAPVVRGIAESNAVVEVRQNGYVIYSTPVPPGAFEITDIYPSGSNGDLEIRITEADGRVRRFTQPYSYLPVMVRRGSLRYAFAAGQYRVQGQSSPKFTQGTLVYGVSDNFTGYGGIIAADNYVAAALGIGMNTRIGGMSLDVTTSRSRTSAGTRQGQSLRFLYSKTLYPTNTTFTMVGYRYSTDGYRTLSQHVEDTDSKYGPRIARQKSRLDVNVNQPLGSGSMFAGVGDTTYWNGEGRSRRFQVGYSNSYRNVSYSVSASHIQESGPFGRPDTQFSVSVSIPLGKASSSHRLYANAVSSTRGDFNVQTGVSGYLNDSNTVNYGVQAGYSRDGGGSGGVSAGWDTPNAKLTGNFTQDRSGRHFDAGASGSVVVHGGGVTLGQPIGETFAVVQVPKVRDVTFGGAPTVRTDRRGYAIVPYLQPYRQNWLNIDPSSVGTHTEITDNAKMVVPTRGAIVKTRFEAESGRRVQFELSQDAGGKVPFGAQAYDAKGKLLGMVDNQSRLLVFGIEDKGSIDVQWGNNSCKVSYQLPTLNKELAYERRAAMCMRAGTVVGAK
>NZ_CP011504.1|WP_047901882.1|855693_856410_+|molecular-chaperone
MKRFHFAGLALAGSLLLSSGASLAGVTLDGTRVVLAAPSKEASILVRNRAPADVMIQSWMDASDGTADVPFAITPALGRLGAEKQQTLRVLYYGQGLPVDRESVFWLNVQEIPQKAQGDNTLQIAVRQRIKFFYRPAGLSGKVEEAPAQLRWKLVQRDGQAQLEVSNPSAYFVSLASVNVKTGGRDYAAAAEMVPPSATRHFAVKDLPAGAAAAGVKVHFESINDYGAVEPHDGTTAG
>NZ_CP011504.1|WP_047901881.1|855046_855640_+|type-1-fimbrial-protein
MKKIAMMMSVAGLAFAAMNAAHAADGTINFTGEIVAASCSITGGNGTSVTGGKGDQSIDVKMGKVSVDALGSTAGGGIAAGTAINLNLDCGATGNGLNTVKVRFDPASGSGVDGTNNKLLKTTGTAKGVGIGIYNTAGTLLNLNANETFDAPLVKGGTEAAPTYTANLALRAGYVKAGTDVEAGTANGTLPFTLTYE
>NZ_CP011504.1|WP_148669121.1|854190_854517_-|hypothetical-protein
MAPIVCDIRMFQTPSYTASQSFTRLSCASTRVIPKCVTIVLTCESDSTGCRRSPRAYPRAENRPDVSNIDGFSMYPGVPRSLTGRVVKNPGQLARVGRADSPVTDIDR
>NZ_CP011504.1|WP_082146268.1|853154_854099_+|acyltransferase
MMQGFVWIALAAAWRRAPGDGQLARDVLASLVIGHVAVSMLFEPDLGSYTRHLSSEALLRPHWLNTTTAAPDYLVKSLLFIPYVKENGHWGPLNLNGWTLEYEMLFYLVVAAALGCARARHATVSAALTLALLCACVAAVDPSGTTVVGHLGQPFVLEFGLGVVAHGVLQAGIAKWVAAPVWAAVAVAAIAAIPLLQMHYGTPDGFARVVLWGGPAFVLIVALVKLDSRGWTIASRTAAALGAASYSIYLIHPYVIGVAGKLAGLRGDPRTGAGLGAACAVLGVACVCGYVCHVWIERPMLKALNLRFLRARRG
>NZ_CP011504.1|WP_047901877.1|850937_851465_-|CS1-type-fimbrial-major-subunit
MKLSKLVLALGVTGALFGMAHTAQADPVSKKITLTAQINDGIFVSKPDGSTWYSTEELDANDYTQTKFSKTLPVRVWTKNPEFNISLAQPLKLSSGYYEMKNAKVQLTSQAGDSEVKFGAQQKITQTTAGNGGFDEIHNLKINVDSPTQVGTQTTNGSYSGDLVMVFEPVAAAAP
>NZ_CP011504.1|WP_047901889.1|872160_875250_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MNKAYSLVWNEAQSGWCAVGETARRRGKSGGGKRLLAAGVSLLGLAAASGAYALPTGGEIASGKADIATSADNKTMSINQHTDKLITNWQDFSVGGGERVSFQQPTSQSIALNRVIGANGSQIHGQIDANGRVFLVNPNGVMFGAGAQVNVGGLVASTQNLSDVDFLAGRYRFAGTSGQSVENAGTITAKERGSVALLGARVSNTGVIRAQMGRVALGAGNAFNVNFDGNGLLNLQVEGGAVDAQAHNGGLLKADGGEVLMTARAAGDLLGSVVKNSGTIEAKGLSSRAGKITLDGGQVHVAGKLDASAQDASTAGGTVTTRGERVVVSRDVQVDTRASSGRTGQWAIEAANAGVDAAGHAITGETLSRNLGTTNVALTNTSGDLTVGDAVNWASDNTLALTSKKGSVDLKQSLTASGANAGVTVNAAQQIRIGNKVALTGENASLALNSGSGHTLTNDDAVVTLSGRNASFSANGEGYRVIHDLAGLRGVDGNMNGRYVLGNAIDGKGAQFRSLGGANAFEGVFDGLGNTISRLTINGNGQYVGLFGMNRGRIANLALDSFAVNEASTGAPASVGALAGANYGGTISNVRVTKTTVSSNGKSSNLVGGLVGDNIAGVIDGARFQGRIAANEAADSIGGIAGRHAFGALITNSHADAEITSMRSSNSMRAVGGLVGRNLHATVSDSTSAGRISVGDRMHAGGLVGQSVNGMIDNATSTVDVSAGKSSFVGGAVGRSDGGTILGSSARGTVRATDGSTVGGFIGLNKGGDIADSKAFGAVNAKGAAAIGGFAGENVDGGVLENVAANGSVSDIASSAVGGLVGRNAGMIRLGEAAGDVRAGQASSAGGLVAVNDGTIEQSKASGVVRAGSESRVGGLVGVNRGTISGSRATGSVYAARDSYAGGLVGENIGQRASIRGSKASGNVTTVGGMFVGGFAGWNNDGALIADSESSGTVAGTGLFAGGFAGVNHGAIRSSHTSSKFDYSEMGMPLVRGGFVAFNSGRIESSNTSGAGAREPFASVNVGWIDGKR
>NZ_CP011504.1|WP_047903674.1|875313_876951_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MCAALICGGAAGLFEPAHAQVPDAGRAMRDIETPRPELPQETAPELTVPPSEEAAESAPESGPRVFVRAFALDGNTVFGSDKLLPLVADLAGSTLSFADLQRAAGRITAYYRRHGYVLARAYLPRQDIDDGVVRIEIAEGRYGAITIQNHSRVLDAALRQPLSALHPGNVVRGPDLERSLLLLDDLAGVGARGTLRPGEMSGTTDLVVDADKGPLASGSLEFDNFGDVALGRYRFGGSVDVNSPLRLGDRLSLRGLVSNELQRYYRAAYQVPVGPASTRVGVAYSSLHYRLGGAFSDLESQGRASVQTAYVTQPLMRARNLSVTAQIQYENKNLRDDYGVFDIRRDKNVGLWTFGVSGNSQDGLLGGGRNGFSVMFGVGRLRSNDPFEADSLKKSIGSFAKLNVSALRVQALGRRFELYTQFSAQLASRNLDESEKFSLGGPYGVRAYALGAGSGDQGWQASAELRYLVAPGWQVSTFVDAGRVQVDKHPWTRGRNMQHMQAGGVGASWYGAKRQVTLTAAWPLGAAIGSPTRAPSVWVQAAQYF
>NZ_CP011504.1|WP_047901890.1|877381_878014_+|LysE-family-translocator
MIDLSTLALFSGACLALTATPGPDMLLIASRSVSQGRRAGFATLAGIQAGTYCHALAAALGLSQLFLAVPIAYDIVRFAGAAYLLYLAWKTFRSDATSLSPVASQRRHSTAAIFRQGLTTNLLNPKMALFVLALFPQFVRPGHGSIAVQILVLATVLNLIGIVVNGAVILSASRLSQRIGARRRPSKLPQYLLGTVFVGLAARLAVAGRN
>NZ_CP011504.1|WP_047901891.1|878044_878332_+|helix-turn-helix-transcriptional-regulator
MTTYIALRKRALANPKIRAEYERLNREEFALLDAMLAARRAAGLSQADVAERMGTKAPAVTRLESALATGRHSPSIDTLRKYAAACGKKLVISFA
>NZ_CP011504.1|WP_047901892.1|878411_879110_-|YebB-family-permuted-papain-like-enzyme
MSIDTGCQPLMSRPLGVSRRRLFTVDSADSVDTHEVSLPVAPEIGDIVFIRVTVRPFLEVASATRSWTNHVGIVVGRRGGEPLVAESTFPLSRVTTMSRFLARSDRGACVIARLKQPLDAAQRRRLVDAAMRRVGVVYDTGFNLASRRQFCSRFVREVVSDATRITLGDVETFDMLLRGNPDHPLGFWKVWYFGRIPWQRRTVTPASLMDSRELRVVVDTRDRADDGCAGGE
>NZ_CP011504.1|WP_047903675.1|879262_879832_-|hypothetical-protein
MQPFNNPWNSLEIVKLVLGVLTPLSVACLGWLVARRLKRLELVQWTNQRLIEKRLALYDAVAPQLNALLCFYTWIGYWKDISPDDVIRAKRELDRTFHIYRYLFDNDVYDAYHTYIHALFDMHTGPGRDARIRSLIQAPDGDRSVHGSYEWKPAWSDRFATANVVPKDDVLRHYTQLMERLRVALGATR
>NZ_CP011504.1|WP_006749370.1|880052_880511_-|Lrp/AsnC-family-transcriptional-regulator
MKLDAIDRRILSALQRDGRMQNVELAHEVGLSPSPCLRRVRLLEEAGVIEKYVAVLNPAKVGKGLTIFTRVWLKGQDAESVNRFADAVQQMPEVVECHLMAGDCDFLLRVVAADIDDYRRFQMETLTRIPGVLSVKTDIPMQKVKLTSALPT
>NZ_CP011504.1|WP_047901893.1|880636_881371_+|AzlC-family-ABC-transporter-permease
MSSSVSTSSGLRDKPAYVAEMGRGLRAALPVMLGFVPFALVLGAQAAQKGLSLFEVPMMTGLNFGGGSEFAAIHLWTSPPHIALIVAMSFLVNSRHILMGAAFEPYIRRLPRRRAFVALFFMCDESWAMSLADARSRSATHISVPYYAGICVGLYLTWISMTTLGAAVGPTIGNVEQYGFDMAFTAVFLVLLRGMWKGMRASRPWFVSLVVAAATHLAVPGAWYVAAGACAGLIAALLWEPRDA
>NZ_CP011504.1|WP_047901894.1|881363_881672_+|AzlD-family-protein
MPELPDFSTVATIVLMASTTYLSRILGYVLLRNRTLSPRMASVMENVPGCVLISVIAPAFVSTRPADLLALAVTLLAATRLSILPTVIVGVASAGLLRHLLG
>NZ_CP011504.1|WP_047901895.1|881849_882629_+|5'/3'-nucleotidase-SurE
MQETRPLFDRVLLTNDDGFDAPGLDVLEQVATQLAREVWIVAPAEDQSGTSHSLSLHEPLRVHRKGERRFAVRGTPGDCVAIAVSHLMKDARPDVVLSGVNRGANLGTETVFSGTVGAAMTSMLLGVPAIALSQAFIDRNAVPWSTALAHAPDVIRRLVAAGWDSDACLNVNFPARPAQDVRGLKVTSQGAGTLQGVEIVSGRDPREIDYHWLKLARAPRDDDADSETVALGEGYVAVTPLKFERTHDGALARLRADLG

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Crispr_ID: NZ_CP011504_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011504_2

1333720-1333884

Orphan

Consensus_repeat	Method
GCGTAAGCGCTAAAGCGCTAACGC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP011504_2

>merge|NZ_CP011504|2|1333720-1333884|CRISPRCasFinder
GCGTAAGCGCTAAAGCGCTAACGCTGATCGACCGCAAAGCATGGGACCCGCGTAAGCGCTAAAGCGCCAACGCGGGTCGACCGCCGTGGGGATGGAGTAAGCGCTGAAGCGCTAACTCCATCCAGCCACGCCATGGGATCAGCGTAACCGCTAAAGCGGTAACGC

>NZ_CP011504|2|1|1333720-1333884|CRISPRCasFinder
GCGTAAGCGCTAAAGCGCTAACGC	TGATCGACCGCAAAGCATGGGACCC
GCGTAAGCGCTAAAGCGCCAACGC	GGGTCGACCGCCGTGGGGATG
GAGTAAGCGCTGAAGCGCTAACTC	CATCCAGCCACGCCATGGGATCA
GCGTAACCGCTAAAGCGGTAACGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011504.1\|WP_047902232.1\|1335650_1336094_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NZ_CP011504.1\|WP_141685094.1\|1322488_1322791_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011504.1\|WP_047902225.1\|1325367_1327350_-\|propionate-catabolism-operon-regulatory-protein-PrpR	unknown	unknown	gnl\|CDD\|226350
NZ_CP011504.1\|WP_034181628.1\|1328464_1329637_+\|2-methylcitrate-synthase	unknown	unknown	gnl\|CDD\|183463
NZ_CP011504.1\|WP_047902221.1\|1321555_1322377_-\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NZ_CP011504.1\|WP_047902230.1\|1335074_1335323_+\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	unknown	unknown	gnl\|CDD\|225072
NZ_CP011504.1\|WP_047902233.1\|1336399_1338019_+\|Tar-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|185008
NZ_CP011504.1\|WP_047902222.1\|1323040_1323889_+\|ureidoglycolate-lyase	unknown	unknown	gnl\|CDD\|223257
NZ_CP011504.1\|WP_047902235.1\|1339215_1339914_+\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
NZ_CP011504.1\|WP_047902223.1\|1324036_1324420_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NZ_CP011504.1\|WP_047902228.1\|1332340_1333534_+\|2-methylaconitate-cis-trans-isomerase-PrpF	unknown	unknown	gnl\|CDD\|131387
NZ_CP011504.1\|WP_047902229.1\|1333903_1334956_+\|CoA-transferase	unknown	unknown	gnl\|CDD\|224717
NZ_CP011504.1\|WP_047902236.1\|1340006_1341521_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235906
NZ_CP011504.1\|WP_047902234.1\|1337991_1339101_-\|AGE-family-epimerase/isomerase	unknown	unknown	gnl\|CDD\|238153
NZ_CP011504.1\|WP_047902231.1\|1335312_1335594_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|224937
NZ_CP011504.1\|WP_148669170.1\|1329721_1332316_+\|Fe/S-dependent-2-methylisocitrate-dehydratase-AcnD	unknown	unknown	gnl\|CDD\|131386
NZ_CP011504.1\|WP_047902224.1\|1324674_1325319_+\|ABATE-domain-containing-protein	unknown	unknown	gnl\|CDD\|227803
NZ_CP011504.1\|WP_047902226.1\|1327520_1328414_+\|methylisocitrate-lyase	unknown	unknown	gnl\|CDD\|183086
NZ_CP011504.1\|WP_167347855.1\|1341696_1341852_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011504.1\|WP_047902237.1\|1342003_1342483_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181

Protein	Function_ID	Function_description	E-value
NZ_CP011504.1\|WP_047902232.1\|1335650_1336094_-\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	3.78065e-25
NZ_CP011504.1\|WP_047902230.1\|1335074_1335323_+\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	gnl\|CDD\|225072	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	3.86269e-10
NZ_CP011504.1\|WP_047902225.1\|1325367_1327350_-\|propionate-catabolism-operon-regulatory-protein-PrpR	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	0
NZ_CP011504.1\|WP_034181628.1\|1328464_1329637_+\|2-methylcitrate-synthase	gnl\|CDD\|183463	PRK12351, PRK12351, methylcitrate synthase; Provisional.	0
NZ_CP011504.1\|WP_047902221.1\|1321555_1322377_-\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	1.20784e-46
NZ_CP011504.1\|WP_047902233.1\|1336399_1338019_+\|Tar-ligand-binding-domain-containing-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	7.45791e-125
NZ_CP011504.1\|WP_047902222.1\|1323040_1323889_+\|ureidoglycolate-lyase	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.84767e-100
NZ_CP011504.1\|WP_047902235.1\|1339215_1339914_+\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	5.23185e-50
NZ_CP011504.1\|WP_047902223.1\|1324036_1324420_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	8.24295e-44
NZ_CP011504.1\|WP_047902228.1\|1332340_1333534_+\|2-methylaconitate-cis-trans-isomerase-PrpF	gnl\|CDD\|131387	TIGR02334, conserved_hypothetical_protein, probable AcnD-accessory protein PrpF. The 2-methylcitrate cycle is one of at least five degradation pathways for propionate via propionyl-CoA. Degradation of propionate toward pyruvate consumes oxaloacetate and releases succinate. Oxidation of succinate back into oxaloacetate by the TCA cycle makes the 2-methylcitrate pathway a cycle. This family consists of PrpF, an incompletely characterized protein that appears to be an essential accessory protein for the Fe/S-dependent 2-methylisocitrate dehydratase AcnD (TIGR02333). This protein is related to but distinct from FldA (part of pfam04303), a putative fluorene degradation protein of Sphingomonas sp. LB126. [Energy metabolism, Fermentation].	0
NZ_CP011504.1\|WP_047902229.1\|1333903_1334956_+\|CoA-transferase	gnl\|CDD\|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	1.91068e-84
NZ_CP011504.1\|WP_047902236.1\|1340006_1341521_+\|hypothetical-protein	gnl\|CDD\|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	0.000121601
NZ_CP011504.1\|WP_047902234.1\|1337991_1339101_-\|AGE-family-epimerase/isomerase	gnl\|CDD\|238153	cd00249, AGE, AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is structurally and mechanistically distinct from the other four types of epimerases. The AGE domain monomer is composed of an alpha(6)/alpha(6)-barrel, the structure of which is also found in glucoamylase and cellulase. The active form is a homodimer. The alignment also contains subtype III mannose 6-phosphate isomerases.	3.62649e-50
NZ_CP011504.1\|WP_047902231.1\|1335312_1335594_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	4.89169e-22
NZ_CP011504.1\|WP_148669170.1\|1329721_1332316_+\|Fe/S-dependent-2-methylisocitrate-dehydratase-AcnD	gnl\|CDD\|131386	TIGR02333, 2-methyl_citrate_dehydratase_Fe-S_dependent_AcnD, 2-methylisocitrate dehydratase, Fe/S-dependent. Members of this family appear in an operon for the degradation of propionyl-CoA via 2-methylcitrate. This family is homologous to aconitases A and B and appears to act the part as 2-methylisocitrate dehydratase, the enzyme after PrpD and before PrpB. In Escherichia coli, which lacks a member of this family, 2-methylisocitrate dehydratase activity was traced to aconitase B (TIGR00117) ().	0
NZ_CP011504.1\|WP_047902224.1\|1324674_1325319_+\|ABATE-domain-containing-protein	gnl\|CDD\|227803	COG5516, COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding [General function prediction only].	1.10158e-27
NZ_CP011504.1\|WP_047902226.1\|1327520_1328414_+\|methylisocitrate-lyase	gnl\|CDD\|183086	PRK11320, prpB, 2-methylisocitrate lyase; Provisional.	0
NZ_CP011504.1\|WP_047902237.1\|1342003_1342483_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.61138e-13

>NZ_CP011504.1|WP_047902228.1|1332340_1333534_+|2-methylaconitate-cis-trans-isomerase-PrpF
MAHIPQIRIPATYIRGGTSKGVFFRLQDLPDAAQAPGAARDALLLRVIGSPDPYGKQIDGMGGATSSTSKTVIVSKSTRPGHDVDYLFGQVAIDKAFVDWTGNCGNLSAAVGPFAISGGLVDPARVPRDGVATVRIWQANIGKTIVAHVPVTNGAVQETGDFELDGVTFPAAEVQLEFMDPAAEEDGAGGSMFPTGNLVDDLAVPGVGTLKATMINAGIPTIFVEAEAIGYTGTELQDAINGDAKALEKFETIRAHGALRMGLIDTLDEIATRQHTPKIAFVAKPADYVASSGKRVNAGDVDLLVRAMSMGKLHHAMMGTAAVAIGTAAAIPGTLVNLAAGGGERNAVRFGHPSGTLRVGAEAQQQENGEWTVTKAIMSRSARVLMEGWVRVPGDAF
>NZ_CP011504.1|WP_148669170.1|1329721_1332316_+|Fe/S-dependent-2-methylisocitrate-dehydratase-AcnD
MNTANRKPLPGTSLDYFDARAAVEAIAPGAYDTLPYTSRVLAENLVRRCDPALLAESLKQIIERKRERDFPWFPARVVCHDILGQTALVDLAGLRDAIADGGGDPAKVNPVVPVQLIVDHSLAVECGGFDPDAFAKNRAIEDRRNEDRFHFIEWTKKAFENVDVIPPGNGIMHQINLEKMSPVIQAQDGVAYPDTCVGTDSHTPHVDALGVIAIGVGGLEAENVMLGRASWMRLPDIVGVELTGKRQPGITATDIVLALTEFLRKEKVVGAYLEFRGEGAASLTLGDRATISNMAPEYGATAAMFFIDGQTTDYLRLTGRSDEQVKLVETYAKAAGLWADTLNNAQYERTLTFDLSSVVRNMAGPSNPHKRLPTSDLAARGIAGQWEEKAGEMPDGAVIIAAITSCTNTSNPRNVIAAALLARNANARGLVRKPWVKSSLAPGSKAVELYLEEANLLPELEKLGFGIVAFACTTCNGMSGALDPKIQQEIVDRDLYATAVLSGNRNFDGRIHPYAKQAFLASPPLVVAYAIAGTIRFDIEKDVLGHDQDGEPVTLKDIWPTDDEIDAIVASSVKPEQFRKVYEPMFARSADAGERAAPLYDWRPQSTYIRRPPYWEGALAGERTLQGMRPLAVLGDNITTDHLSPSNAILLDSAAGEYLAKMGLLEEDFNSYATHRGDHLTAQRATFANPTLINEMAVVDGAVKKGSLARVEPEGKVMRMWEAIETYMNRKQPLIVVAGADYGQGSSRDWAAKGVRLAGVEAIAAEGFERIHRTNLIGMGVLPLEFKPGTNRTTLGIDGTETFDVIGERKPRADLTLVIHRRNGERVEVPMTCRLDTAEEVSIYEAGGVLQRFAQDFLESSQAA
>NZ_CP011504.1|WP_034181628.1|1328464_1329637_+|2-methylcitrate-synthase
MSETKDAAAPAAAGAFKPKKSVALSGVTAGNTALCTVGKTGNDLHYRGYDILDVAESCEFEEIAHLLVHGTLPNLTELAAYKTKLRALRGLPSALKAALEQIPASAHPMDVMRTGVSVLGTVLPEKDDHNLPGARDIADRLMASLGSMLLYWYHFSHNGKRIETETDDDSIGGHFLHLLHGKTPSKSWVEAMHTSLILYAEHEFNASTFTGRVIAGTGSDIYSAITGAIGALRGPKHGGANEVAYEIQSRYSSPDDAEADIRRRVENKEVVIGFGHPVYTISDPRNKVIKGVAHKLSKEAGDTKLYNIAERLESVMWEAKKMFPNLDWFSAVSYHMMGVPTAMFTPLFVISRTSGWSAHIIEQRIDNKIIRPSANYTGPEDLQFVPIEKR
>NZ_CP011504.1|WP_047902226.1|1327520_1328414_+|methylisocitrate-lyase
MSNTHLQSAGAKFRAAVAAEQPLQVVGAITAYAAKMAQAVGFKAVYLSGGGVAANSLGIPDLGISTMEDVLIDANRITNATDLPLLVDIDTGWGGAFNIARTVRSFIKAGVAAVHMEDQVGQKRCGHRPGKEVVPTEEMVDRIKAAVDARTDEQFVIMARTDAAAAEGIDSAIERAVAYVEAGADMIFPEAMKTLDDYRRFKAAVKVPILANLTEFGSTPLFTLDELREANVDIALYCCGAYRAMNKAALNFYETLRRDGTQKAAVPTMQTRAELYDFLGYHEYERKLDELFAQGKK
>NZ_CP011504.1|WP_047902225.1|1325367_1327350_-|propionate-catabolism-operon-regulatory-protein-PrpR
MDLSSTKPVGPADRAARPRIWAMGISRLRELFREIAGEFDERADVRIVTRAYEDALTAIAEAGAARPDVIVAAGSNGAFLKTRAQVPVVVVSPTGFDVMQALARARRDAARIALVSAGETPPEVRRFVAAYGLDVQFASYQSAQEAEACVHDLRDRGIETIVGPGLVTDLAASAGMGAVFLYSHASVRKAVDTALEVAYATHAEAFRRQRLDNLLQHLRDGVVALDARGRVEAINERLASALGVEPAAAVGRALVDLRPELRTLRGEDGDALATVRGVRYVVHRGPLVDRGVTSGSVLTFQESRAVERLDRALRSQPTTQQFAARYALDDVIGASTPMARVRDLVRRYAKSDATVLVLGESGTGKEMIAQSLHALSARRSYPFVAVNCGAFPEALLESELFGYEEGAFTGARRGGKTGLFEAAHRGTLFLDEIGEMPPSLQSRLLRVLQEREVIRLGSTEPIRIDVRVIAATHRPLLAAVEAGTFRADLYYRLNILNVGLPPLRERAADIPALAATLLVQAARREPRLAERLRDAGDAARVLGATQATLARYRWPGNVRELQNVIERIAVELAEEVDENDPAAACAALDPDALQAIAPELFAAPPDAADTDDTQTLHARRRRAEADEIRAVLDACGGDRDRACAMLGISKTTLWRKLSAK
>NZ_CP011504.1|WP_047902224.1|1324674_1325319_+|ABATE-domain-containing-protein
MVVRYDGVMSDTQPSVTMDCLIPAPPETLSIDFANTLYWRGSDLPTETFGTMDDLLVWCREQAGVPAGLADRCRVRGVEEGEPAMLARALALREALYRLFHAQAERREPQADDLALLGGFLAEASPRVALARVDGGYAWRIGDAGATLAALLSPVLWSAIDLLGGARLAKVKRCANDACQWLFIDDSKNGSRRWCSMSSCGNRAKAYRHYHKAD
>NZ_CP011504.1|WP_047902223.1|1324036_1324420_-|VOC-family-protein
MIDHLSFGVAHIGRSRAFYDSTLGALGYKRLYGDDGSIGYGTTEPQLWLQHAARPVAADPESGLHLSFKAASPVEVDAFYRAALEHGGQDNGGPGKREHYGPGYYAAFVVDPDGYRLEAHCELDNVV
>NZ_CP011504.1|WP_047902222.1|1323040_1323889_+|ureidoglycolate-lyase
MKLLRYGPSGQEKPGMLDADGRIRDLSAHVPDLAGDVLSDAGLARLRAIDPATLPLVSGEPRIGACVGHVGKFIGIGLNYADHAAEAGMPVPKEPVVFGKWTSSICGPNDGIDIPKGSVKTDWEVELGVVIGARCKDVDEASALDYVAGYCVVNDVSEREWQIERGGQWDKGKGFDTFGPIGPWLVTRDEVPDPQRLDLWLEVDGHRYQNGNTRTMVFTVAQLIAYLSTCMTLQPGDVITTGTPPGVGMGIKPSPIFLKAGQMVRLGIDGLGEQLQHTRGAQ
>NZ_CP011504.1|WP_141685094.1|1322488_1322791_-|hypothetical-protein
MPADFTRGRTVAGPQAFVPSAARREMTRDGYRLLVHLQTLRRNIGRTRAARSAAQAGIACHLGMNTGYSGCPCHRKRLPIRSYPVMIGKKTLHCTLFVYC
>NZ_CP011504.1|WP_047902221.1|1321555_1322377_-|IclR-family-transcriptional-regulator
MQTTNDPLPGSDARESMAAIDRYRAPALDKGLDILELLSEQKEGLTRTEITKELGRNASEIYRMLERLVARRYVMRSTGGDRYTLSLKLFALAHRHPPMSRLIAEALPPMQRFADAAEQSCHLSVYDRGNLLVIAQVDGPGPWGVSVRLGSRVGLADTASGRVMLSFQGPEQRTHMLAEHRKVKGEAALNEQELAYACQSIRQDGYLRQDSRQAYGVTDLTAPILGPAGQAIAVLTCPYMRRIDAHAAPSVDVVAAGLRDTAAHLSMGRTETC
>NZ_CP011504.1|WP_047902229.1|1333903_1334956_+|CoA-transferase
MPLDAPLSGIHIVEFEGLGPGPLAGWMLAGMGARITLIARPSGRTSAPDALRGRDGDLLREGKTIVELDLKTPAGRDAALELIAQADALIEGLRPGVMERLGLGPEDCARRNPKLVYGRMTGWGQHGPLAAAAGHDLNYVALTGLLSLSAPRDGRPGLPPTVVGDAGGALGLAFGIVCALFDVRGGGPGRVVDGAIVDIVSMLGSLALWARANGQLDGTQPSLFHDAPFYDVYRCADGECVTIGALEPPFYTLLVERLGLTDVDPASQYDRAHWPALKARFADVFAQQPSAHWRALLEGTDACFAPVLSVADAAAHPHNAARGIYRIDENGNVRARVAPRFLPLTGGGAE
>NZ_CP011504.1|WP_047902230.1|1335074_1335323_+|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin
MPHTILASVTASVSELKRNPMGTVAAGEGFPVAILNHNEPAFYCIPAKTWEAMVERLEDIEDNALADSRAKEKAVKVKLNDL
>NZ_CP011504.1|WP_047902231.1|1335312_1335594_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MTFELAFLEAALKEWKKLDRTVRDQFKARLAERLENPRIPSAKLHGHPDRYKIKLRSVGYRLVYEVRDSEVVVLVVAVGRRERDAVYLAAMKR
>NZ_CP011504.1|WP_047902232.1|1335650_1336094_-|PaaI-family-thioesterase
MTDITDHARGALRAQPFSMLLGTELMHIGDNEVSLCLHVRDELRQQHGFVHGGVISYLADNALTFAGALVLGPRVITAEYKINYLRPAVNGTLVARAKLVYAGRHQATCQCHVFVIDGDHERLVAIAQGTINRVGDGKVPDMPEETA
>NZ_CP011504.1|WP_047902233.1|1336399_1338019_+|Tar-ligand-binding-domain-containing-protein
MFGKIKLASGLLGVLTVFCLFLFAIEALGFWALASTRSGVDDLSNVAIAQVNSANQATEHLLDARINLSRAGTRMVRGGPKPEDIIRHAGASLAEADKAFAALTAAQPVDDTNRARVAALAERYRALRGALGELVQFLDADNIQAFLDQPTQGIQDAYIAELHRFAEYGSASSRTALDTIDGGMLWFKSVGIALLVAMLAASAAIYAAARRAVVAPLDEAGRHFERIAQGRLDEAVRAGGVFEIDRMLRGLAAMQTSIAGTVRTVRHASDAIHLGAGEIAGGNADLSARTGTQAASLEETAASMEELTATVRQNTDSARAASALADAALEATGHGGGVVDSVIDRMRGIAQSSGRIAEIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAQSAKEIKALIEDSVAQINGGAELVERAGEAMRTVSASITRVVQTMSEITAASVEQSVGIEQVNQAVTQMDQLTQQNAALVEEVAAAAASLNDQTAHLMQAVSVFELGDGRAARGERAAPSFADAGYEPAGSAA
>NZ_CP011504.1|WP_047902234.1|1337991_1339101_-|AGE-family-epimerase/isomerase
MSVSDSASAQAAQLRHHFAHIVLPIWRGSGFDHTLQLPFEAVDPATHAPLPVTRYRAMACARQLFVFAQAGDAAHAATLFDALCSRFRDARHGGWIYSVDAHGAPLDTSKDLYTHAFIVFACAAWHAASGDAAARTMAEETAALIQDRFAPRRGDALLDAARHADFSSSGSGALQNPLMHLTEAWLAAADAFGDAAFDDALFNTAQAVERTFVDTATGCVAELPLGAADNRFEPGHQFEWFYLVDAAGARLAQTGLPGALSRAFAFAEQYGVDAHTGGVCAALDAQGACIDGTQRIWAQTEYLRALATHGGTPASAPLAQQIERFAARFLHPRGWFECKTADGQVSRADLPSTTPYHLATAYAALPAGS
>NZ_CP011504.1|WP_047902235.1|1339215_1339914_+|MgtC/SapB-family-protein
MLSNLELVMRLVLAAALGSVIGFERERLSWAAGLRTHMLVCVGSTLIMIVSAFGFADVLGSSEHIVLDPSRIAAQVVSGIGFLGAGSILLRGEIVRGLTTAASLWSVAAIGLAVGGGLYVASISATIIILIILAGIKPLERRYFTVRQRRQLALTVVSGALTFDSLHAALGPDSARVKQFILQRADDTGEHDEVRIALARVSELEYRAICDKLRALKGVTRFEEGNGLSGDE
>NZ_CP011504.1|WP_047902236.1|1340006_1341521_+|hypothetical-protein
MTESVSTPRSRSRSNRSSARSRQRSAAAAGSTSARATSRHGSAPAGDAQRDELTLDLFGDPVLEPGERVLVTAEAEAAIGAADDAAAGRQASLDGFSAPEGTSAVGHAEADGAVKPEVAAASGDVSAPEGGDAANARGVSAADGVAIKVIDVPAADGVAAKVAYVPAADGVAVKAADVPAAVGVATKAADVPAADGVAAKAADVSAADGVAAKAADVSAADGATATATGPQAADGAVAKTADRHATDGEITKAAVEAAAVKSREGRSSGDAVKERRSSSAGKRRAAAGASDATSVQSAPVATSVDKAPDATGSNPVPDVASTVESQTPAQPADPAIVANPAPPRDAAPTNASSSPVMQPVASAASFVTKPSSERAQPAAPAFDPDTHLRPLTDRLAALQADVDGLTRTADREMRRVNRLLLALAVVVLAGLVALMLQTRQIAHLKQDAATKQQRIDRLAADLSTQQATLMTLEEHHEALLSQVDRLQRNANREAAVAKRARRTR
>NZ_CP011504.1|WP_167347855.1|1341696_1341852_+|hypothetical-protein
MSFILALLQKIDDLFVSPHLPLDADYSYAARRAEVERVRRAHLVPIVLYRR
>NZ_CP011504.1|WP_047902237.1|1342003_1342483_+|GNAT-family-N-acetyltransferase
MLLMRPMTAGEFHAYRTRAIDGYARDLVSSGQNAVEDAADRARACFDTLLPDGLRTSGQILVVLIDGATGDAVGDLWYAIVPEGPNRTLFIYDLDIVPSRRRQGWATRALEALDAEARRYGITEIGLSVFNHNTAARALYRACGFAPITTTLIKPVIPG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP011504_2	2.2\|1333793\|21\|NZ_CP011504\|CRISPRCasFinder	1333793-1333813	21	NZ_CP011503.1	1398529-1398549	1	0.952
NZ_CP011504_2	2.1\|1333744\|25\|NZ_CP011504\|CRISPRCasFinder	1333744-1333768	25	NZ_CP011503.1	3381885-3381909	2	0.92

1. spacer 2.2|1333793|21|NZ_CP011504|CRISPRCasFinder matches to position: 1398529-1398549, mismatch: 1, identity: 0.952

gggtcgaccgccgtggggatg	CRISPR spacer
gggccgaccgccgtggggatg	Protospacer
***.*****************

2. spacer 2.1|1333744|25|NZ_CP011504|CRISPRCasFinder matches to position: 3381885-3381909, mismatch: 2, identity: 0.92

tgatcgaccgcaaagcatgggaccc	CRISPR spacer
tggtcgaccgcgaagcatgggaccc	Protospacer
**.********.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011504_2	2.2\|1333793\|21\|NZ_CP011504\|CRISPRCasFinder	1333793-1333813	21	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	361277-361297	1	0.952
NZ_CP011504_2	2.3\|1333838\|23\|NZ_CP011504\|CRISPRCasFinder	1333838-1333860	23	MF417947	Uncultured Caudovirales phage clone 3F_8, partial genome	10757-10779	2	0.913
NZ_CP011504_2	2.3\|1333838\|23\|NZ_CP011504\|CRISPRCasFinder	1333838-1333860	23	NZ_CP028585	Escherichia coli strain WCHEC4533 plasmid p1_000533, complete sequence	21940-21962	3	0.87
NZ_CP011504_2	2.3\|1333838\|23\|NZ_CP011504\|CRISPRCasFinder	1333838-1333860	23	NZ_CP032875	Escherichia coli strain WCHEC000837 plasmid p1_000837, complete sequence	628-650	3	0.87
NZ_CP011504_2	2.3\|1333838\|23\|NZ_CP011504\|CRISPRCasFinder	1333838-1333860	23	NZ_LT905089	Salmonella enterica subsp. enterica serovar Typhi strain ty3-243 genome assembly, plasmid: 1	13489-13511	3	0.87
NZ_CP011504_2	2.3\|1333838\|23\|NZ_CP011504\|CRISPRCasFinder	1333838-1333860	23	NZ_CP022228	Escherichia coli strain WCHEC96200 plasmid p1_000200, complete sequence	41511-41533	3	0.87

1. spacer 2.2|1333793|21|NZ_CP011504|CRISPRCasFinder matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 1, identity: 0.952

gggtcgaccgccgtggggatg	CRISPR spacer
gggtcgaccgccgtggcgatg	Protospacer
**************** ****

2. spacer 2.3|1333838|23|NZ_CP011504|CRISPRCasFinder matches to MF417947 (Uncultured Caudovirales phage clone 3F_8, partial genome) position: , mismatch: 2, identity: 0.913

catccagccacgccatgggatca	CRISPR spacer
catccagccacgtcataggatca	Protospacer
************.***.******

3. spacer 2.3|1333838|23|NZ_CP011504|CRISPRCasFinder matches to NZ_CP028585 (Escherichia coli strain WCHEC4533 plasmid p1_000533, complete sequence) position: , mismatch: 3, identity: 0.87

catccagccacgccatgggatca	CRISPR spacer
cagccagccacgccatgggatac	Protospacer
** ******************

4. spacer 2.3|1333838|23|NZ_CP011504|CRISPRCasFinder matches to NZ_CP032875 (Escherichia coli strain WCHEC000837 plasmid p1_000837, complete sequence) position: , mismatch: 3, identity: 0.87

catccagccacgccatgggatca	CRISPR spacer
cagccagccacgccatgggatac	Protospacer
** ******************

5. spacer 2.3|1333838|23|NZ_CP011504|CRISPRCasFinder matches to NZ_LT905089 (Salmonella enterica subsp. enterica serovar Typhi strain ty3-243 genome assembly, plasmid: 1) position: , mismatch: 3, identity: 0.87

catccagccacgccatgggatca	CRISPR spacer
cagccagccacgccatgggatac	Protospacer
** ******************

6. spacer 2.3|1333838|23|NZ_CP011504|CRISPRCasFinder matches to NZ_CP022228 (Escherichia coli strain WCHEC96200 plasmid p1_000200, complete sequence) position: , mismatch: 3, identity: 0.87

catccagccacgccatgggatca	CRISPR spacer
cagccagccacgccatgggatac	Protospacer
** ******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1054180 : 1114959

Escherichia_phage(16.67%)

bacteriocin,plate,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141685150.1\|1054180_1055306_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.3e-58	43.8
WP_047902030.1\|1056895_1057939_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_047898708.1\|1059216_1059990_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	5.5e-81	57.6
WP_047898709.1\|1059986_1061015_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.6e-72	44.1
WP_082146181.1\|1061090_1062155_-	alanine racemase	NA	NA	NA	NA
WP_047902032.1\|1062173_1063250_-	fatty acid desaturase	NA	NA	NA	NA
WP_047902033.1\|1063332_1063908_-	hypothetical protein	NA	NA	NA	NA
WP_047902034.1\|1063904_1064915_-	hypothetical protein	NA	NA	NA	NA
WP_047902035.1\|1064926_1066084_-	MFS transporter	NA	NA	NA	NA
WP_047902036.1\|1066977_1067850_+	histidine kinase	NA	NA	NA	NA
WP_047902038.1\|1068384_1069800_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.8e-13	32.4
WP_082146182.1\|1069787_1070585_-	FkbM family methyltransferase	A0A0P0C5Z9	Ostreococcus_mediterraneus_virus	6.6e-05	28.3
WP_047902039.1\|1070871_1072722_-	ATP-dependent endonuclease	E5E3R2	Burkholderia_phage	2.5e-23	26.5
WP_047902040.1\|1073167_1074250_-	hypothetical protein	NA	NA	NA	NA
WP_047902041.1\|1074422_1074725_-	hypothetical protein	NA	NA	NA	NA
WP_047902042.1\|1074974_1075592_+	LysE family translocator	NA	NA	NA	NA
WP_047903701.1\|1075699_1075948_+	hypothetical protein	NA	NA	NA	NA
WP_047902043.1\|1076005_1077364_-	MFS transporter	NA	NA	NA	NA
WP_047902044.1\|1077661_1078048_-	4-carboxymuconolactone decarboxylase	NA	NA	NA	NA
WP_047902045.1\|1078058_1078844_-	3-oxoadipate enol-lactonase	A0A249XTE1	Mycobacterium_phage	2.8e-08	35.2
WP_047902046.1\|1078843_1080217_-	3-carboxy-cis,cis-muconate cycloisomerase	A0A1B3B081	Gordonia_phage	1.4e-05	28.7
WP_047903702.1\|1080305_1080962_-	CoA transferase subunit B	NA	NA	NA	NA
WP_047902047.1\|1080975_1081692_-	3-oxoacid CoA-transferase subunit A	NA	NA	NA	NA
WP_047902048.1\|1081835_1083068_-	4-hydroxybenzoate 3-monooxygenase	NA	NA	NA	NA
WP_047902049.1\|1083234_1084161_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_047902050.1\|1084250_1084880_+	GTP cyclohydrolase I FolE	A0A2I7S8W4	Vibrio_phage	1.2e-44	45.9
WP_047902051.1\|1084879_1085683_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_047902052.1\|1085712_1086633_-	serine acetyltransferase	NA	NA	NA	NA
WP_047902053.1\|1086761_1086995_-	hypothetical protein	NA	NA	NA	NA
WP_047902054.1\|1087272_1087683_+	DUF3005 domain-containing protein	NA	NA	NA	NA
WP_047902055.1\|1088273_1088741_+	universal stress protein	NA	NA	NA	NA
WP_047902056.1\|1088843_1089590_+	fumarate/nitrate reduction transcriptional regulator Fnr	NA	NA	NA	NA
WP_047902057.1\|1089638_1090532_-	LysR family transcriptional regulator ArgP	NA	NA	NA	NA
WP_047902058.1\|1090642_1091263_+	amino acid transporter	NA	NA	NA	NA
WP_047903703.1\|1091687_1092635_+	aldo/keto reductase	NA	NA	NA	NA
WP_047902059.1\|1093108_1094077_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_047902060.1\|1094230_1095796_+	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0SI18	Klosneuvirus	1.8e-54	30.9
WP_047902061.1\|1095882_1096863_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_047902062.1\|1097047_1097581_+	2,4'-dihydroxyacetophenone dioxygenase family protein	NA	NA	NA	NA
WP_047902063.1\|1097599_1098904_+	MFS transporter	NA	NA	NA	NA
WP_047902064.1\|1098905_1100027_+	2,3-butanediol dehydrogenase	NA	NA	NA	NA
WP_047902065.1\|1100004_1100727_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	1.5e-08	35.5
WP_047902066.1\|1100903_1101995_+	porin	NA	NA	NA	NA
WP_047902067.1\|1102415_1102988_+	hypothetical protein	NA	NA	NA	NA
WP_047902068.1\|1103125_1105363_-	TOMM precursor leader peptide-binding protein	NA	NA	NA	NA
WP_047902069.1\|1105438_1105804_-\|bacteriocin	BMA_0021/BMA_0022 family TOMM bacteriocin	NA	NA	NA	NA
WP_047902070.1\|1105820_1106165_-\|bacteriocin	BMA_0021/BMA_0022 family TOMM bacteriocin	NA	NA	NA	NA
WP_047903704.1\|1106198_1110236_-	TOMM system kinase/cyclase fusion protein	A0A2H4UW49	Bodo_saltans_virus	1.8e-13	26.3
WP_047902071.1\|1110232_1111234_-	FHA domain-containing protein	NA	NA	NA	NA
WP_047902072.1\|1112109_1112487_+	DUF3592 domain-containing protein	NA	NA	NA	NA
WP_047902073.1\|1112508_1113081_+	hypothetical protein	NA	NA	NA	NA
WP_047902074.1\|1113081_1114959_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP011505

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

298381 : 307950

Escherichia_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047904096.1\|298381_299218_+	alpha/beta hydrolase	A0A249XU20	Mycobacterium_phage	5.7e-07	27.4
WP_047904097.1\|299738_300011_-	hypothetical protein	NA	NA	NA	NA
WP_148669184.1\|300346_300655_-	hypothetical protein	NA	NA	NA	NA
WP_082146306.1\|300828_301482_-	YitT family protein	NA	NA	NA	NA
WP_047904099.1\|301695_302700_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.7e-80	46.6
WP_047904100.1\|302696_303581_-	dTDP-4-dehydrorhamnose reductase	A0A1D7XFA3	Escherichia_phage	4.3e-29	34.8
WP_047904101.1\|303577_304150_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	2.4e-49	53.1
WP_047904102.1\|304146_305043_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	9.8e-98	58.8
WP_082146340.1\|305084_306398_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	2.4e-28	30.1
WP_047904104.1\|306451_307171_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.9e-14	28.7
WP_047904105.1\|307167_307950_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	7.2e-12	28.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP011503

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1275246 : 1284916

uncultured_Mediterranean_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006756934.1\|1275246_1276353_+	DNA polymerase III subunit beta	R9TRR6	Rhizobium_phage	2.4e-45	31.4
WP_047899369.1\|1276546_1279021_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	6.7e-112	34.3
WP_082146050.1\|1279443_1279791_+	lysozyme	K4I410	Acidithiobacillus_phage	1.4e-20	68.0
WP_047899370.1\|1279982_1280180_+	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	3.2e-17	54.8
WP_047901093.1\|1280246_1281290_+	DNA cytosine methyltransferase	A0A0R6PG08	Moraxella_phage	1.4e-108	56.5
WP_047899371.1\|1281308_1281767_+	very short patch repair endonuclease	V5UTF4	Oenococcus_phage	3.8e-13	38.7
WP_047899372.1\|1281787_1284916_+	DEAD/DEAH box helicase family protein	A0A1B1IUI1	uncultured_Mediterranean_phage	2.5e-95	29.2

DBSCAN-SWA_2

2022572 : 2031665

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047899868.1\|2022572_2024525_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	1.2e-145	48.8
WP_047899869.1\|2024790_2025927_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	9.1e-24	39.5
WP_047899870.1\|2025931_2027854_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VNU7	Pandoravirus	1.2e-57	37.6
WP_047899871.1\|2028003_2028819_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	9.7e-36	31.7
WP_047899872.1\|2028862_2029549_-	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	9.4e-08	26.4
WP_047899873.1\|2029545_2030088_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_047899874.1\|2030123_2031665_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	3.0e-22	30.6

DBSCAN-SWA_3

2266517 : 2277001

Bacillus_virus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900051.1\|2266517_2267636_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	4.0e-24	35.3
WP_047900052.1\|2267728_2268352_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_047900053.1\|2268338_2269118_-	Smr/MutS family protein	A0A0P0IDT4	Acinetobacter_phage	2.2e-13	32.4
WP_047900054.1\|2269253_2270216_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	6.0e-61	43.3
WP_047900055.1\|2270616_2272926_+	DNA translocase FtsK	G1FGP1	Mycobacterium_phage	1.4e-84	50.0
WP_047901156.1\|2272972_2273662_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_047900056.1\|2273838_2275149_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	3.2e-81	40.2
WP_047900057.1\|2275188_2275455_-	DUF2164 domain-containing protein	NA	NA	NA	NA
WP_047900058.1\|2275699_2277001_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.8e-92	50.1

DBSCAN-SWA_4

2357184 : 2365481

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900123.1\|2357184_2358585_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.1e-76	38.3
WP_053059933.1\|2358592_2359543_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	5.8e-16	27.4
WP_047900124.1\|2359606_2360599_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	7.7e-27	30.9
WP_047900125.1\|2360672_2361035_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_047900126.1\|2361249_2362152_+	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	5.7e-53	40.2
WP_082146085.1\|2362218_2363562_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_011351344.1\|2363605_2364529_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	5.1e-41	34.9
WP_047900128.1\|2364560_2365481_-	alpha/beta hydrolase	Q6TUZ7	Yaba_monkey_tumor_virus	1.5e-16	27.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011504

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP011505

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP011503

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection