CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012022	Corynebacterium pseudotuberculosis strain 262 chromosome, complete genome	3 crisprs	cas1,cas6e,cas8e,cse2gr11,cas7,cas5,DEDDh,cas3,WYL,cas4,csa3,DinG	0	2	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012022_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012022_1

25684-26017

TypeI-E

I-C,I-E,II-B

Consensus_repeat	Method
GGAACTACCTCCGCATACGCGGAGAAAAG	PILER-CR
GGAACTACCTCCGCATACGCGGAGAAAAG	CRISPRCasFinder
GGAACTACCTCCGCATACGCGGAGAAAAG	CRT

5 spacers

cas2,cas1,cas6e,cas8e,cse2gr11,cas7,cas5

The CRISPR arrays of NZ_CP012022_1

>merge|NZ_CP012022|1|25684-26017|PILER-CR,CRISPRCasFinder,CRT
GGAACTACCTCCGCATACGCGGAGAAAAGCAACTTGCTCTAAAACCGTCTGGCGAAAACACGGAACTACCTCCGCATACGCGGAGAAAAGCCGCCTGGCGCAAAGATAAAGACGGCAATACCGGAACTACCTCCGCATACGCGGAGAAAAGGAGAATGAGAAATGATGAAACCGACCGAGCCGGGAACTACCTCCGCATACGCGGAGAAAAGACACACACGGCCTGGACATCAAACAAAATTCCGGAACTACCTCCGCATACGCGGAGAAAAGTGAAGGAAAACAGCCTATACCGTGCGCATATCGGAACTACCTCCGCATACGCGGAGAAAAG

>NZ_CP012022|1|1|25684-26017|PILER-CR
GGAACTACCTCCGCATACGCGGAGAAAAG	CAACTTGCTCTAAAACCGTCTGGCGAAAACAC
GGAACTACCTCCGCATACGCGGAGAAAAG	CCGCCTGGCGCAAAGATAAAGACGGCAATACC
GGAACTACCTCCGCATACGCGGAGAAAAG	GAGAATGAGAAATGATGAAACCGACCGAGCCG
GGAACTACCTCCGCATACGCGGAGAAAAG	ACACACACGGCCTGGACATCAAACAAAATTCC
GGAACTACCTCCGCATACGCGGAGAAAAG	TGAAGGAAAACAGCCTATACCGTGCGCATATC
GGAACTACCTCCGCATACGCGGAGAAAAG

>NZ_CP012022|1|1|25684-26017|CRISPRCasFinder
GGAACTACCTCCGCATACGCGGAGAAAAG	CAACTTGCTCTAAAACCGTCTGGCGAAAACAC
GGAACTACCTCCGCATACGCGGAGAAAAG	CCGCCTGGCGCAAAGATAAAGACGGCAATACC
GGAACTACCTCCGCATACGCGGAGAAAAG	GAGAATGAGAAATGATGAAACCGACCGAGCCG
GGAACTACCTCCGCATACGCGGAGAAAAG	ACACACACGGCCTGGACATCAAACAAAATTCC
GGAACTACCTCCGCATACGCGGAGAAAAG	TGAAGGAAAACAGCCTATACCGTGCGCATATC
GGAACTACCTCCGCATACGCGGAGAAAAG

>NZ_CP012022|1|1|25684-26017|CRT
GGAACTACCTCCGCATACGCGGAGAAAAG	CAACTTGCTCTAAAACCGTCTGGCGAAAACAC
GGAACTACCTCCGCATACGCGGAGAAAAG	CCGCCTGGCGCAAAGATAAAGACGGCAATACC
GGAACTACCTCCGCATACGCGGAGAAAAG	GAGAATGAGAAATGATGAAACCGACCGAGCCG
GGAACTACCTCCGCATACGCGGAGAAAAG	ACACACACGGCCTGGACATCAAACAAAATTCC
GGAACTACCTCCGCATACGCGGAGAAAAG	TGAAGGAAAACAGCCTATACCGTGCGCATATC
GGAACTACCTCCGCATACGCGGAGAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012022.2\|WP_048588391.1\|20406_21177_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NZ_CP012022.2\|WP_048588395.1\|36491_37415_+\|phospholipase-D	unknown	unknown	gnl\|CDD\|176518
NZ_CP012022.2\|WP_048588394.1\|35042_36083_-\|transposase	unknown	unknown	gnl\|CDD\|371130
NZ_CP012022.2\|WP_087907622.1\|30072_30783_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09727_cas6e_CAS-I-E	gnl\|CDD\|187858
NZ_CP012022.2\|WP_013240878.1\|19808_20345_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223725
NZ_CP012022.2\|WP_145951878.1\|24069_24249_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_158521261.1\|21195_21369_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_087907524.1\|22741_24010_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP012022.2\|WP_048588396.1\|37467_38334_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NZ_CP012022.2\|WP_087907530.1\|34275_34968_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP012022.2\|WP_014366221.1\|19059_19731_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_048588390.1\|16772_17546_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP012022.2\|WP_145951877.1\|22436_22661_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_087907529.1\|33193_34264_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP012022.2\|WP_087907527.1\|26407_27361_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP012022.2\|WP_032802276.1\|32600_33194_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0096_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP012022.2\|WP_087907528.1\|30993_32604_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cls000721_cas8e_CAS-I-E	unknown
NZ_CP012022.2\|WP_145951876.1\|21892_22144_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_087907526.1\|26035_26407_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
NZ_CP012022.2\|WP_087907525.1\|24265_25609_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853

Protein	Function_ID	Function_description	E-value
NZ_CP012022.2\|WP_048588391.1\|20406_21177_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	6.07907e-21
NZ_CP012022.2\|WP_048588395.1\|36491_37415_+\|phospholipase-D	gnl\|CDD\|176518	cd08576, GDPD_like_SMaseD_PLD, Glycerophosphodiester phosphodiesterase-like domain of spider venom sphingomyelinases D, bacterial phospholipase D, and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase-like domain (GDPD-like) present in sphingomyelinases D (SMases D) (sphingomyelin phosphodiesterase D, EC 3.1.4.4) from spider venom, the Corynebacterium pseudotuberculosis Phospholipase D (PLD)-like protein from pathogenic bacteria, and the Ajellomyces capsulatus H143 PLD-like protein from ascomycetes. Spider SMases D and bacterial PLD proteins catalyze the Mg2+-dependent hydrolysis of sphingomyelin producing choline and ceramide 1-phosphate (C1P), which possess a number of biological functions, such as regulating cell proliferation and apoptosis, participating in inflammatory responses, and playing a key role in phagocytosis. In the presence of Mg2+, SMases D can function as lysophospholipase D and hydrolyze lysophosphatidylcholine (LPC) to choline and lysophosphatidic acid (LPA), which is a multifunctional phospholipid involved in platelet aggregation, endothelial hyperpermeability, and pro-inflammatory responses. Loxosceles spider venoms' SMases D are the principal toxins responsible for dermonecrosis and complement dependent haemolysis induced by spider venom. Due to amino acid substitutions at the entrance to the active-site pocket, some members lack activity. The typical GDPD domain consists of a TIM barrel and a small insertion domain named as the GDPD-insertion (GDPD-I) domain, which is specific for GDPD proteins. Although proteins in this family contain a non-typical GDPD domain which lacks the GDPD-I, their catalytic mechanisms are based on Mg2+-dependent acid-base reactions similar to GDPD proteins. They might be divergent members of the GDPD family. Moreover, this family does not belong to phospholipase D (PLD) superfamily, since it lacks the conserved HKD sequence motif that characterizes the catalytic center of the PLD superfamily. It belongs to the superfamily of PLC-like phosphodiesterases.	2.22241e-90
NZ_CP012022.2\|WP_048588394.1\|35042_36083_-\|transposase	gnl\|CDD\|371130	pfam10551, MULE, MULE transposase domain. This domain was identified by Babu and colleagues.	0.00185796
NZ_CP012022.2\|WP_087907622.1\|30072_30783_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	3.99503e-34
NZ_CP012022.2\|WP_013240878.1\|19808_20345_+\|peptidylprolyl-isomerase	gnl\|CDD\|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	7.32899e-65
NZ_CP012022.2\|WP_087907524.1\|22741_24010_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.6046e-31
NZ_CP012022.2\|WP_048588396.1\|37467_38334_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	2.17856e-115
NZ_CP012022.2\|WP_087907530.1\|34275_34968_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	3.5046e-28
NZ_CP012022.2\|WP_048588390.1\|16772_17546_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	6.167e-102
NZ_CP012022.2\|WP_087907529.1\|33193_34264_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.09617e-79
NZ_CP012022.2\|WP_087907527.1\|26407_27361_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	3.46006e-72
NZ_CP012022.2\|WP_032802276.1\|32600_33194_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	5.93072e-07
NZ_CP012022.2\|WP_087907526.1\|26035_26407_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	5.44078e-22
NZ_CP012022.2\|WP_087907525.1\|24265_25609_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.55213e-49

>NZ_CP012022.2|WP_087907525.1|24265_25609_+|IS3-family-transposase
MRARSSLSEYQREQLVECFEQGMGCKSAANALGVSRHAVQSLYRRFVLRGRLCLVEKPTKQHYPFEVKKEVVERHLAGETIMDLAREFGLSSDQLIKDWSRKWRKDGDEALKPKSKGRPKGSAAPKRLTEEEKLRRQIARLEAENAYLKKIAGLEESGTRLKVQAIVILKSYHRLEYLLEAAGIPRSTFFYHQRRLSGPDKHAAIKDAIRESFERNKHRYGYRRVLLDLRNRGWVVNHKLVYKLMRKMGLRAKIRQHRPYASYAGTISHIADNKLDRKFTPDTPNTVFVSDVTEFRVAGRKVYLSPVMDLFDRSIVAHTVATSPSTAFTADSLSKAIAACAPEPGWMMHTDQGFQYQHSSWRNLIGDNGGVQSMSRKANCYDNAVMENFFGHVKTEMYHGDVFDTVEEFNQAIDEYIQWYNTKRIQQRLKGLTPMQYRNQTLEPLTA
>NZ_CP012022.2|WP_145951878.1|24069_24249_+|hypothetical-protein
MLEITDSRLSGGRDIQELPPHTRRKAPTMGRPWDLGWNYLRIRGIELLPVGWTEKSVTD
>NZ_CP012022.2|WP_087907524.1|22741_24010_-|MFS-transporter
MTIFKTNPSYRSWFTADMSGEIARQIVFSSMTLLAYSVTHDVKQTGFIAALMALTRFISMLAASWVVDFYPKRRLMVINALCRIVLSASVVVLLITGHMGFISLIAVAIGYGAIGGIFGNLTNAILPFIVDELELKDALSLNETRDSIIQIAAAPLSVFLFSMLRALPFIVDIMGFAIVAIGARYIHGVIDAEHSNELSPGITHTLQEFWERSTAGMRWVAHHHGIRAILALMTLNGLSSFLVINTVELNILDSDQPVWHVGAVFACFSAGMVCGGIISGPLRKAFSNHQIIIITSTISTITMACLSIMDHWMIVGTLLAVWTLPVIANNAVLGASQMIATPSKLQGRVGAAFGLIIGLTPILGASSAGLLLDNLGWQFTIMLATGIGIGGLTIAIFSQALRGIINEQNSPQRSSGGRASKS
>NZ_CP012022.2|WP_145951877.1|22436_22661_-|hypothetical-protein
MSNPTPPIIKNRAGIPRPATEAPVRARRRFAGGLGAASAGLLEAIDGVAGGGTDVVVVVGGTGGISGSSGSPWQ
>NZ_CP012022.2|WP_145951876.1|21892_22144_+|hypothetical-protein
MEKPYECHNLLNCTPQHVSVEFPYGISPNSSPLISLLTISTEKPALGSTVYNTAEVNGRKISGSVTFPSAGGQGAGKQRRVYD
>NZ_CP012022.2|WP_158521261.1|21195_21369_+|hypothetical-protein
MLWDRLRDLAALFLCVGLSSVDSFNLLNTSVYTQPRWTIAHLNYKHGIYARIYGVIH
>NZ_CP012022.2|WP_048588391.1|20406_21177_+|rhomboid-family-intramembrane-serine-protease
MFHENGGMSDPRILHAAYKQAPVTVLLSLSTLIIFLITAFQSQSITDNLYDSWIGTHWILYTPEMHEPLGMLRAIGSMFLHIGPGHLAINIFLLFFLGREIEQCIGSALFCAAYFISGLGASLMIMIMDPLSPTAGASGAIYGLMAIMVAIAVTRKTDIRAPLILVAVNVGYSLIADNVSLWGHIGGLIAGSVVALPLMAFHRKHVIAGGTGGFLVYGTPRNHRAFTKDRLITWFVVAAIVVCEAIGIWIVGMKLL
>NZ_CP012022.2|WP_013240878.1|19808_20345_+|peptidylprolyl-isomerase
MMVRMTLKTATAILHTNRGDVAIELFGNHAPKTVENFVTLSDGSADYKTENASGTTEGPFYDGAVFHRIIDGFMIQGGDPTGTGRGGPGYMFADEFHPELQFDRPFLLAMANAGPGTNGSQFFITVVPTPHLNNHHTIFGEVTDPASQKVVMDIAQTATDRMDRPVEPVVIESVEITE
>NZ_CP012022.2|WP_014366221.1|19059_19731_-|hypothetical-protein
MNSSTIRGAILVTKAAYDKYANYRDRKTREAYDALLNAADSYDDIHKDVKANVTEFYDQSQERVSSLTEQARKRLDSAIADAAAAKDNTVKTVNKKSKKAQKAARKAAKSAKKSAAPKKQPSFGKRLFNFSVFTTILATIGAVAYYFLSKRDVVSTEPPHVEDFGADSVNTEESRLVYSTQTPVDDEEEHVSSPEEGATERDEKLLGSLEDQLRQHTDSKDTK
>NZ_CP012022.2|WP_048588390.1|16772_17546_+|sugar-ABC-transporter-ATP-binding-protein
MDTSTTPIIELRDITKSYGAFDALRGVNLSVASGEVTCVLGDNGAGKSTLIKILSGLHKQSSGELLIDGQPVTFSGPREALDNGIATVHQNLAVVGQMSVWRNFFLGQELTGFLGRLRESEMRSIAQEQLKTMGIDLPDIDVEVESLSGGQRQVVAIARAVYFGARVIILDEPTAALGVKQSGMVLRFVAAARDKGLGVVLITHNPHHAYLVGDRFTILNLGNQILNASRDQVTLEQLTQQMAGGGELEALSHELSR
>NZ_CP012022.2|WP_087907526.1|26035_26407_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MFAVIQGHNLPEHLNGYLSRFLSEVDAGLYVGVLSRAVMENLWEKCQSVDLAGSLTLIHPQYDAEQGFRIRTTGKQRRPVVDLDGLFLSARGLIEDVRFADPLDEADAIIPDEVLEDFCPESE
>NZ_CP012022.2|WP_087907527.1|26407_27361_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MSYSNEALAFSTIPASEQIRLEDRVSFLYLEYCLIRQDRTGVIAVSRGDEKAPAELKDLPIKARIQLPVGGIAVLMLGPGTSISQPAATSCARAGVSVLFTGGGGVQAYSLSTPLTSSARWAIAQARLASNEAKQRTAARILYKRQLGIEEIEADSIAVMRGIEGRTIRNLYKRLSAKYKIKNFKRDTNATDPVNTNLNLGNSILYGCAASACAALGINPALGIIHRGDIRSLLFDLADLYKPTLTIPAAFKCANNDDDGSEFRRLVRSEIVKQDLLKNMIHIMMEILAPHLPERTDDRLIGGRNREVPGHRQYGGT
>NZ_CP012022.2|WP_087907622.1|30072_30783_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MPKATYWTHFPAHIALNKSLILGDFATENSKNKPHWDIDDPVFRHRAVMALFPEHQSDNARADSNILFRLEVLPGQEPYFFIQSSIKPSNHNLDKHIETRQVDLMSPEAGTPIEFRLSINAVRRKTIDAAKDAKRKIKTTCLPLDALSSDPTETSAGQWVKEKLSPALENIDIVRHGRQVLGANRNGKKTSARTVQVDTIDGFAHVKDPAELQKILIHGIGRAKSYGCGMLTFRPI
>NZ_CP012022.2|WP_087907528.1|30993_32604_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MKSNVFKDFPFIKTNKGPMTVEEFFHSSHEKSLHLDLSIPGYEYGAIWRLLTSLTAVLMQRDPLFLKGKETSSELRFDPEFISQILDDLGSKISLTEGKNLFFQRPLLEGENPKDTARYVGPGKDPAWKLSPTAPSEKSQVYWNLEKLKPESLEAVDAIVALMVFSMYSFTGNSKYDGAKCLNGSPGIRFLGGGNTATEFIIEAQTPLLSLLKSIPLEWCEPGGLPAWLDRTGAESRKPNGEMHPLWRATWSSNTAACCWDGETLVGVGIGGIPPEWYALEMGSKPEARKEWWDQRNTEDPFYFYQPDKGGVLKAKRLDLSRDLTELAVEWVAEDLSTALAERVRGRALRVDFKEDSLLFIRHQIGGNASSAMIRESVVSQARKQQWVFDPTGALQKQVRGKADFILSLRNIVLSPFRRENKSDRDRGRRVLDSLASERPKMNETFWREIAPIYEEFILYFTEQVSGDETRKEVRAQAKKTLKELGKDAVRTAQKAFDMVLEPYLLQNPSQAYEVRRRIHSYLASTIAETNEGDQK
>NZ_CP012022.2|WP_032802276.1|32600_33194_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTTSRPKQSWTPLVAEFAQRKKDKEFRAKRSALRAGAGTYTEFRAYSYVLPFLGEKASAAQRTALLRCMAALAEYPDVVSSGEKATASSVGQWVNRVAFDGKQGQSEPDSMVASRIKYLHTQDLEEAISSLRRIMAFADRKNVTTKLNPYQFVELFWYWGNGFTDASTKHRLSVLRDFYSTKQKENTDPQSSSEGEK
>NZ_CP012022.2|WP_087907529.1|33193_34264_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSRHLTIHVVASVPYSNLNRDDSGTPKNVRRGGVTCALLSSQSIKKGIRTKYEDASLDTSVRSGRIADDVLERAKVLAPEADTKALEKAVKKIIGTLTKAAEVNESEDESDRSIWLSAEELEAAAVSVVEQAEKKDFIEDGRTGSLAIAAFGRMFAAAPKKGTEAALSVSPAVTTHGVTIATDYFSTIDDIRERNRDVAGATYLGVAQYTTGVFYRTVTIDKEQLRESWTGLDREDAKENLAALVNAIIYGLPRGKQHSTAPFVQPALILAEEQSYRCAYDFESPVQADAREGGYLKPTMEELKRQYDSARAFDADNFGETQVVSGTYPEVSELFAGAKYADKNGFIDEVVAWIQR
>NZ_CP012022.2|WP_087907530.1|34275_34968_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTTTSVYLRLAGPLQSWAGPAVTGNFVRTAPIPTHSALVGLIAGAFGYRRDEWPDWLDRLSFRVRVDHPGKFVDDFQTVSAHEEEMLFRERLIFATGKRPSAKTTRLTPDGRGMTSIIQRTYLAEAEFIVEVASDTHGELLRDALRSPKFSTYLGRKAFAPAFPFFLGATADVDVLHRIPACDLSGTKRDTTRVQIHHRSAGLQTSAEHINVPAVQERSDWLEKTKALFT
>NZ_CP012022.2|WP_048588394.1|35042_36083_-|transposase
MIMASHPYRNHCNVCGNLLKKNGKTSTGKTRYRCKGCGASSTATRSGTLHQRQMKDFITWLLGPTSRYNNDISRAQRRSMSWCWQVPVPQPEMLDNAYILVMDKGASFRPEHLLVAYDSAHVLGWKWVDKDNKTACMQVHAQFPQPSAVVIDGGQSTAQAIQAIWPGIPVRRCLSHIRKSVDQKTSQTPRTQPAIEIKELTDSLKNVYTSKQAKLWLARYARWEDRWKELLKHRTNVSKDNCSIEGCDWEWTHKELRTIRFMYRKLIKKEELFLPFSGSDIVAHNVILSRRDSQLGETISTDITNLFSAHRGINHDHGCRMVEWYLNSKTESPFIPERIISHDHWR
>NZ_CP012022.2|WP_048588395.1|36491_37415_+|phospholipase-D
MREKVVLFLSIIMAIMLPVGNAAAAPVSHNPASTANRPVYAIAHRVLTTQGVDDAVAIGANALEIDFTAWGRGWWADHDGIPTSAGATAEEIFKHIADKRKQGANITFTWLDIKNPDYCRDARSVCSINALRDLARKYLEPAGVRVLYGFYKTVGGPAWKTITADLRDGEAVALSGPAQDVLNDFARSENKILTKQKVADYGYYDINQGFGNCYGTWNRTCDQLRKSSEARDQGKLGKTFGWTIATGQDARVNDLLGKANVDGLIFGFKITHFYRHADTENSFKAIQRWVDKHSATHHLATVADNPW
>NZ_CP012022.2|WP_048588396.1|37467_38334_-|ABC-transporter-ATP-binding-protein
MHTPKTTSTDLPTTAGISTDHTSALRTENVTLSWDKHVVSTDLSVDIPTGKFTAIIGPNGCGKSTLLKSCARILAPDTGSIYLNQHNLTHLHTKEIAKQLALLPQSTITPADITVEELVRRGRFPHHNWLHQWTAEDTRAVDAALNAASVKELTHKRVTDLSGGQRQRVWLAMVLAQNTPTVLLDEPTTFLDIAHQYQLLELARSLTTQLNRTVVAVLHDLQQAVRYADHLIVMKNGSIVATGSPQEVISAELISEVFNITVRTMLIDDQLIVIPAELPVPNVAMMQG

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP012022_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012022_2

1837535-1837747

Orphan

I-C,I-E,II-B

Consensus_repeat	Method
CGGAACTACCTCCGCGTGCGCGGAGAAAAGA	PILER-CR
CTTTTCTCCGCGCACGCGGAGGTAGTTCC	CRISPRCasFinder
CTTTTCTCCGCGCACGCGGAGGTAGTTCC	CRT

3 spacers

DinG

The CRISPR arrays of NZ_CP012022_2

>merge|NZ_CP012022|2|1837535-1837747|PILER-CR,CRISPRCasFinder,CRT
TCTTTTCTCCGCGCACGCGGAGGTAGTTCCGACGGATGGCTAAAAGGAAACGCCCTGAAATACTTTTCTCCGCGCACGCGGAGGTAGTTCCGCACCCAGACTTCACGTATTCGTGATGGTGCTCTTTTCTCCGCGCACGCGGAGGTAGTTCCACTAAAAAGCTTCATCAGGCGGCCCCCTCTAGCTTTTCTCCGCACACGCGGAGGTAGTTCC

>NZ_CP012022|2|2|1837535-1837687|PILER-CR
TCTTTTCTCCGCGCACGCGGAGGTAGTTCCG	ACGGATGGCTAAAAGGAAACGCCCTGAAAT
ACTTTTCTCCGCGCACGCGGAGGTAGTTCCG	CACCCAGACTTCACGTATTCGTGATGGTGC
TCTTTTCTCCGCGCACGCGGAGGTAGTTCCA

>NZ_CP012022|2|2|1837536-1837747|CRISPRCasFinder
CTTTTCTCCGCGCACGCGGAGGTAGTTCC	GACGGATGGCTAAAAGGAAACGCCCTGAAATA
CTTTTCTCCGCGCACGCGGAGGTAGTTCC	GCACCCAGACTTCACGTATTCGTGATGGTGCT
CTTTTCTCCGCGCACGCGGAGGTAGTTCC	ACTAAAAAGCTTCATCAGGCGGCCCCCTCTAG
CTTTTCTCCGCACACGCGGAGGTAGTTCC

>NZ_CP012022|2|2|1837536-1837747|CRT
CTTTTCTCCGCGCACGCGGAGGTAGTTCC	GACGGATGGCTAAAAGGAAACGCCCTGAAATA
CTTTTCTCCGCGCACGCGGAGGTAGTTCC	GCACCCAGACTTCACGTATTCGTGATGGTGCT
CTTTTCTCCGCGCACGCGGAGGTAGTTCC	ACTAAAAAGCTTCATCAGGCGGCCCCCTCTAG
CTTTTCTCCGCACACGCGGAGGTAGTTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012022.2\|WP_013242513.1\|1828184_1828952_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293802
NZ_CP012022.2\|WP_158521272.1\|1837838_1838015_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_155719860.1\|1839669_1839963_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_158521273.1\|1839398_1839542_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_072577915.1\|1843190_1843490_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_072577913.1\|1841982_1842207_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_048589206.1\|1835956_1837240_-\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NZ_CP012022.2\|WP_087907633.1\|1838724_1839033_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_048589205.1\|1835462_1835960_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP012022.2\|WP_087907598.1\|1830896_1831433_-\|DUF2017-domain-containing-protein	unknown	unknown	gnl\|CDD\|378185
NZ_CP012022.2\|WP_080562512.1\|1841270_1841423_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|309782
NZ_CP012022.2\|WP_048480964.1\|1841596_1841833_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|309782
NZ_CP012022.2\|WP_048589204.1\|1833444_1835439_+\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NZ_CP012022.2\|WP_048589203.1\|1832033_1833392_+\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236426
NZ_CP012022.2\|WP_129559145.1\|1841362_1841521_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|309782
NZ_CP012022.2\|WP_087907601.1\|1842347_1843178_+\|EndoU-domain-containing-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_032802570.1\|1827411_1828146_-\|ribonuclease-PH	unknown	unknown	gnl\|CDD\|178914
NZ_CP012022.2\|WP_048589200.1\|1829024_1829918_-\|glutamate-racemase	unknown	unknown	gnl\|CDD\|234851
NZ_CP012022.2\|WP_048589201.1\|1829991_1830810_-\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NZ_CP012022.2\|WP_032802571.1\|1831527_1831827_-\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809

Protein	Function_ID	Function_description	E-value
NZ_CP012022.2\|WP_013242513.1\|1828184_1828952_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293802	cd07716, RNaseZ_short-form-like_MBL-fold, uncharacterized bacterial subgroup of Ribonuclease Z, short form; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. Members of this bacterial subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	4.17064e-75
NZ_CP012022.2\|WP_048589206.1\|1835956_1837240_-\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.66101e-94
NZ_CP012022.2\|WP_048589205.1\|1835462_1835960_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.36713e-23
NZ_CP012022.2\|WP_087907598.1\|1830896_1831433_-\|DUF2017-domain-containing-protein	gnl\|CDD\|378185	pfam09438, DUF2017, Domain of unknown function (DUF2017). This is an alpha-helical domain found in gene neighborhoods that contain genes encoding ubiquitin, cysteine synthases and JAB peptidases.	7.76319e-73
NZ_CP012022.2\|WP_080562512.1\|1841270_1841423_-\|hypothetical-protein	gnl\|CDD\|309782	pfam04796, RepA_C, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood.	0.000159495
NZ_CP012022.2\|WP_048480964.1\|1841596_1841833_-\|hypothetical-protein	gnl\|CDD\|309782	pfam04796, RepA_C, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood.	2.16083e-15
NZ_CP012022.2\|WP_048589204.1\|1833444_1835439_+\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	6.8101e-153
NZ_CP012022.2\|WP_048589203.1\|1832033_1833392_+\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
NZ_CP012022.2\|WP_129559145.1\|1841362_1841521_-\|hypothetical-protein	gnl\|CDD\|309782	pfam04796, RepA_C, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood.	0.000436858
NZ_CP012022.2\|WP_032802570.1\|1827411_1828146_-\|ribonuclease-PH	gnl\|CDD\|178914	PRK00173, rph, ribonuclease PH; Reviewed.	5.09274e-164
NZ_CP012022.2\|WP_048589200.1\|1829024_1829918_-\|glutamate-racemase	gnl\|CDD\|234851	PRK00865, PRK00865, glutamate racemase; Provisional.	8.74607e-134
NZ_CP012022.2\|WP_048589201.1\|1829991_1830810_-\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	1.14434e-22
NZ_CP012022.2\|WP_032802571.1\|1831527_1831827_-\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	6.42082e-37

>NZ_CP012022.2|WP_048589206.1|1835956_1837240_-|phosphoserine-phosphatase-SerB
MIELDQPQVTVSLRPELTPAVITISGQDRQGVSAAAFRVLAANGVQILDVEQSQFRGFLGLAVFAGVEASKVEILEVGLKETLKTYGQNVKIELQEVAQSSRPRSTHEVVILGNPVEAHDLSRVAQTLANFDANIDTIRGISDYPVTGLELKITVAKREPGAAMPLRKALAELTAELGVDIAIERTGLLRRSKRLICFDCDSTLITGEVIEMLAAHAGREKEVAEVTERAMCGELDFEESLRERVKALAGLDASVIGEVADSIELTPGARTTIRTLKRLGYKTAVVSGGFIQVLEELAEDLGLDYVRANTLEVVDGKLTGRVIGRIVDRAAKAEFLEEFARESGIEMHQTVAVGDGANDIDMISAAGLGIAFNAKPALREIADTSVNSPFLDEVLHMLGITRADIDAADDSEGKIRRVPLPQQKNEY
>NZ_CP012022.2|WP_048589205.1|1835462_1835960_+|GNAT-family-N-acetyltransferase
MTAHVPPLSNDSVKLRPLLLSDAHDLTATCRDPLTQKYTTVPANYTFAMAEEFIKTEHDNLRWVITVPTSDRFCGQIELRSLATEHNAMNVGYMTAPWARGQGLMTSALLLAVDYAFSRSVRRIELQADSQNKASQRVAEKAGFILMDSSQDTMVYSLLADEYHS
>NZ_CP012022.2|WP_048589204.1|1833444_1835439_+|ATP-dependent-DNA-helicase
MLDATSTLCPMSDSPLALSTDELLDAAVAALGGSRRNGQVSMANAVTKALESERHLAVQAGTGTGKSLAYLVPALRHAQATDSTIIVSTATIALQRQLVERDLPRLADALEPHMSRRPTFAIMKGRANYVCMNKIAAAEEPEDALIDEEDLSWLGKHVARIYEWANETEVGDRDSLDPGVPDLAWRQVSVNAQECIGASRCPHGEECFAELARKKAHDVDVIVTNHALLAIDALSDVNVLPEHEVVIVDEAHELDGRITAVATNEIGVTALTMSSRRAGKLGAGEKDQKLIDIAKEWEDAMLAIEPGRLTSLPDSLKQQTVALRDAIWSLREHISRVPEGEAANDPERHAERMSLSNHLNDQHDSVIRVLSVFEEEDAASQEDVVWVLHDERRGVMIKVAPLSIAGLLHTRLFSENTVVLASATLNIGGNFNAMAASWGLPKGSWDSLDAGTPFNPATSGILYTPNSLPDPGRDGLSPEVLDEIYELIMAAGGRTLGLFSSRRAAQQATDAMRTRLPFDVLCQGDDTTGALVEKFSKQENTCLFGTLSLWQGVDVPGRSCSLVIIDRIPFPRPDDPLLQARKDAADADGRNGFMEVAATHAALLIAQGAGRLLRSVTDRGVVAILDRRIVTKRYGAFFIRSLPAFWRTNDPQVVRGALSRLVAR
>NZ_CP012022.2|WP_048589203.1|1832033_1833392_+|nicotinate-phosphoribosyltransferase
MSCASALSVFKAKLVCVTEFESTALLTDMYELTMLQSALADGTASRSCTFEVFSRRLPNERRYGVVAGTARVLEAIKHYRFTEEQLASLTFLDATTIDFLRSYKFQGQIDGYREGELYFPSSPILTIRGTFAECVILETLILSIMNADSAVASAAARMVTAADGRPIFEMGSRRTHEYAAVTAARAAYLAGFVGTSNLEAVHRYGIPGSGTAAHAWTLLHVNDDGTPNESAAFQSQINVLGVGTTLLVDTYDIAKGVKTAIEVAGPQLGAVRIDSGDLGVMTRKVRQELDSLGAHNTGIVVSSDLDEYAIAGLRGNPVDAFGVGTSVVTGSGAPTAGMVYKLVEVDGHPVAKRSRGKAMVGGTKRAIRTHRATGTAVEEIVFPYDHDTPQIGQLNSYELTIPLMRNGIAVDNLPTLEESRAYLAEQLITLPWEGLALSKDEPVLSTRFIGFK
>NZ_CP012022.2|WP_032802571.1|1831527_1831827_-|ATP-dependent-Clp-protease-adapter-ClpS
MSSPMATPELDEALSVDVASSENLPWMCIVWDDPVNLMSYVTYVFQTILGYSKRRAIELMMQVHTEGKAVVSSGERDKVEGDVKKLHTAGLWATMQQGG
>NZ_CP012022.2|WP_087907598.1|1830896_1831433_-|DUF2017-domain-containing-protein
MQPWKKKKGLMRGVHFACVFEPMEREVLGNLASTVSEALIHRAQSAPKDELAELTGMPSGHKEAPKDPALARLLPDFEKEGDEEFEGDNSLLRCLHETDITRAKIEHLYVLGQALGPDGGVHVDITEAEAHAWVAALNDIRLYVASGEVFGEDAEQDRESLVEWLAYNQESLLNAMMG
>NZ_CP012022.2|WP_048589201.1|1829991_1830810_-|rhomboid-family-intramembrane-serine-protease
MSLRYFFTRLCFIMMNRFNPYAQSDKKTYGGVSTSGGYLPHEYGTQYLPTSDYPVNRAVQRGVKRTSLRSMGRKRLADATVLALGYVVVIWAVHIVNTVFFGGTLAQELGVHPLDGSSIWHIFTSPLVHGSYMHISANTLPGLIFVFLIGLSGRRPFWEVTMITAVVGGMGTWIFGGIGTTHIGASGLIYGWLTYLVVRGIFNKSFSQVVLGVVLAFMYGGLIWGVLPGDVGVSWQAHLFGAIGGLIAGATITSDDPPALKARREQQALHRA
>NZ_CP012022.2|WP_048589200.1|1829024_1829918_-|glutamate-racemase
MAYVKKDLGADSLHPEAPSVKPSVVYEGTIDASSPIGIFDSGVGGLTVARAIMEQLPQESVIYIGDTANSPYGSKPIAQVREFSMRIGDELVARGCKMIVIACNTATSAALRDLRERYSIPVVGVILPAVRRAVAATRNGKIGVLGTQGTIASGAYQELFAASPGVEVYAQACPSFVSFVERGITSGRQILGVAQGYTEGLQSAGVDTLVLGCTHYPLLTGVIQLAVGDNVTLISSSEECVKDVLKVLSRNDMLAEATADKPPSRSFESTGDPALFEQLAMRFLGPHVTYVEKLRQV
>NZ_CP012022.2|WP_013242513.1|1828184_1828952_-|MBL-fold-metallo-hydrolase
MKLTILGSSGSLGAPDNAASGYLIQMDNAPSILMDMGPGVLAQLERAQNPSDAHVVFSHLHADHCVDFPSLLVWRRYHPTAAAKGRNLCFGPTDTPVRLGRLSADSVDNIDDMSDTFAFTPWQNAKEELVGAVSITPYSVVHPIESFALRVEHKRSGKVVAYSGDSSYTENLIECARDADVFLCEATWGETSEGKVPNMHMSGEEAGRIARIAGAKRLILVHIPPWGNAKAALEKARSEFDGPVDISYQGMEIHI
>NZ_CP012022.2|WP_032802570.1|1827411_1828146_-|ribonuclease-PH
MTTSNFKRADGRAVDQMRTVKITRGFTTNPAGSVLVEFGNTRVMCTASAEIGVPRFKRDSGEGWLTAEYAMLPAATLDRNPRESMRGKVKGRTHEISRLIGRSLRAAVDLSELGENTINIDCDVLQADGGTRTASITGAYVALADAISHLQKQGVVPGNPLKDPVAAVSVGVIDGAVCLDLPYEEDSRADVDMNVIMQNGRFVEIQGTGEHNTFDRDELARILDFAEKGCTELVAAQKAALGIA
>NZ_CP012022.2|WP_158521272.1|1837838_1838015_-|hypothetical-protein
MAINLEQAKLNTLEDYEPTVIDEFRKESVVLDSLAFDTAVNPAGGGATLSYGYRRLAT
>NZ_CP012022.2|WP_087907633.1|1838724_1839033_-|hypothetical-protein
MIDNIYNRIERETGGKVFYGIGVDPTNQDNISIDAGYVEALLEYGYLDVSLKKEFLELWLTDEEYEDLEALDFVQDLTYKMLLQYADMEPRVDISSFLHKAA
>NZ_CP012022.2|WP_158521273.1|1839398_1839542_+|hypothetical-protein
MISKLEAEMSEMLGKYYEAVHYIRKLHLAYPDAVDANPVPDELEQDF
>NZ_CP012022.2|WP_155719860.1|1839669_1839963_+|hypothetical-protein
MPGLDFFCVPEGESGAEVCYVAWCASVGYVGAPCSFADVAVVGTVFDTPEFASGVFVGDGGVHWWLLLEMMAARVSRVSASIVQAAIVIVVVGRKSR
>NZ_CP012022.2|WP_080562512.1|1841270_1841423_-|hypothetical-protein
MLRPHRRYPIPIDLDILQKLGKPRAMDIYVWITMKKAALHYQNRSSLTLG
>NZ_CP012022.2|WP_129559145.1|1841362_1841521_-|hypothetical-protein
MNQPIADEWKLWLDASNPDQADLEDSYIQLTKRFFDLIADTPSPLTLISSRS
>NZ_CP012022.2|WP_048480964.1|1841596_1841833_-|hypothetical-protein
MITKSPNGLPYGKYPRLIMAYVITSAVVRSHQVEQGYLTAEEARKIPLGESMNEFFRRIGGTTRGTGGNTGTITRIRE
>NZ_CP012022.2|WP_072577913.1|1841982_1842207_+|hypothetical-protein
MSKIKDPKSVLRGLASALLGVIAYCAVVAPVFKEGSYWESAKESFSTIGVGFSAAIVLVGVLWLVIIHFANKSQ
>NZ_CP012022.2|WP_087907601.1|1842347_1843178_+|EndoU-domain-containing-protein
MHGGNYLRARGGKGRRALWSALRCGQSLSEAEQDKHFTKAGAEALRNGADYVEVVNSMQGMTGIGDDVKPFTRYGAPRSGWRRLSVPEIMRRADGDEDRMRELLLQYRYIRPERRYGPVSRVDFSKGWPHDSDNLGELAQELPKNDPRPVPSSKDWAHILDGEPIVPRKKIQGGHRYGTGRERKTEFPRWWSDVDIKKAVLLTIEAPHASKVFGTTRVLYRVVDEVLVQVSYYPAPDSSGSMILGASYPKNGSGVVKNIGGRAVEQPLDVSLVPRE
>NZ_CP012022.2|WP_072577915.1|1843190_1843490_+|hypothetical-protein
MIEIVNRQLVDADALAIMDSVWNQLPNDLRAYAASSCDDDEDVSAVIAILDYALATGLSVSKAALSKARSLAEKLSRDVDARRILELAAGLNEAGTKAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP012022_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012022_3

2126067-2126151

Orphan

Consensus_repeat	Method
GTACCACCAGCCGCCGTGCCGCCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012022_3

>merge|NZ_CP012022|3|2126067-2126151|CRISPRCasFinder
GTACCACCAGCCGCCGTGCCGCCAGCGGCAGTGCCTCCAGCTGCAACGCCTCCTACGGCCGTACCACCAGCCGCCGTACCGCCAG

>NZ_CP012022|3|3|2126067-2126151|CRISPRCasFinder
GTACCACCAGCCGCCGTGCCGCCAG	CGGCAGTGCCTCCAGCTGCAACGCCTCCTACGGCC
GTACCACCAGCCGCCGTACCGCCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012022.2\|WP_048589323.1\|2133056_2133533_-\|urease-accessory-protein-UreE	unknown	unknown	gnl\|CDD\|238320
NZ_CP012022.2\|WP_048589313.1\|2119239_2120880_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173883
NZ_CP012022.2\|WP_048589320.1\|2129230_2130241_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238568
NZ_CP012022.2\|WP_048589310.1\|2114431_2115793_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP012022.2\|WP_014801045.1\|2118163_2119159_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_CP012022.2\|WP_048589311.1\|2115836_2116502_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213224
NZ_CP012022.2\|WP_087907614.1\|2106818_2112416_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP012022.2\|WP_048589318.1\|2127044_2127356_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238042
NZ_CP012022.2\|WP_048589314.1\|2121103_2122708_-\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
NZ_CP012022.2\|WP_048589322.1\|2132356_2133076_-\|urease-accessory-protein-UreF	unknown	unknown	gnl\|CDD\|223900
NZ_CP012022.2\|WP_048589308.1\|2112418_2113204_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012022.2\|WP_048589325.1\|2135443_2135755_-\|urease-subunit-beta	unknown	unknown	gnl\|CDD\|237303
NZ_CP012022.2\|WP_048589321.1\|2130839_2131718_-\|urease-accessory-protein-UreD	unknown	unknown	gnl\|CDD\|223899
NZ_CP012022.2\|WP_048589315.1\|2122947_2123460_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240308
NZ_CP012022.2\|WP_048589317.1\|2126378_2127035_+\|DUF1707-domain-containing-protein	unknown	unknown	gnl\|CDD\|377959
NZ_CP012022.2\|WP_058093289.1\|2116494_2118171_-\|dipeptide/oligopeptide/nickel-ABC-transporter-permease/ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_CP012022.2\|WP_013242776.1\|2131718_2132333_-\|urease-accessory-protein-UreG	unknown	unknown	gnl\|CDD\|349776
NZ_CP012022.2\|WP_048589324.1\|2133666_2135376_-\|urease-subunit-alpha	unknown	unknown	gnl\|CDD\|237305
NZ_CP012022.2\|WP_048589319.1\|2128144_2129212_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP012022.2\|WP_048589309.1\|2113208_2114084_-\|class-C-sortase	unknown	unknown	gnl\|CDD\|320676

Protein	Function_ID	Function_description	E-value
NZ_CP012022.2\|WP_048589323.1\|2133056_2133533_-\|urease-accessory-protein-UreE	gnl\|CDD\|238320	cd00571, UreE, UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The C-terminal region of UreE contains a histidine rich nickel binding site.	5.76326e-33
NZ_CP012022.2\|WP_048589313.1\|2119239_2120880_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173883	cd08518, PBP2_NikA_DppA_OppA_like_19, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	5.11376e-160
NZ_CP012022.2\|WP_048589320.1\|2129230_2130241_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238568	cd01148, TroA_a, Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.70954e-51
NZ_CP012022.2\|WP_048589310.1\|2114431_2115793_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	1.49695e-66
NZ_CP012022.2\|WP_014801045.1\|2118163_2119159_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	4.81696e-83
NZ_CP012022.2\|WP_048589311.1\|2115836_2116502_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213224	cd03257, ABC_NikE_OppD_transporters, ATP-binding cassette domain of nickel/oligopeptides specific transporters. The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.	8.14739e-63
NZ_CP012022.2\|WP_087907614.1\|2106818_2112416_-\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	1.08263e-10
NZ_CP012022.2\|WP_048589318.1\|2127044_2127356_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	8.90464e-11
NZ_CP012022.2\|WP_048589314.1\|2121103_2122708_-\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	2.32327e-52
NZ_CP012022.2\|WP_048589322.1\|2132356_2133076_-\|urease-accessory-protein-UreF	gnl\|CDD\|223900	COG0830, UreF, Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones].	5.43545e-47
NZ_CP012022.2\|WP_013242776.1\|2131718_2132333_-\|urease-accessory-protein-UreG	gnl\|CDD\|349776	cd05540, UreG, urease accessory protein UreG. UreG is one of the four accessory proteins of urease. Urease is an enzyme which catalyzes the decomposition of urea to form ammonia and carbon dioxide. Bacterial urease is a trimer of three subunits which are encoded by genes ureA, ureB, and ureC. Up to four accessory proteins (ureD, ureE, ureF, and ureG) are required for urease catalytical function. UreG may play an important role in nickel incorporation of the urease metallocenter. UreG is a member of the Fer4_NifH superfamily which contains an ATP-binding domain. Proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.	4.19847e-120
NZ_CP012022.2\|WP_048589325.1\|2135443_2135755_-\|urease-subunit-beta	gnl\|CDD\|237303	PRK13203, ureB, urease subunit beta; Reviewed.	2.90343e-62
NZ_CP012022.2\|WP_048589321.1\|2130839_2131718_-\|urease-accessory-protein-UreD	gnl\|CDD\|223899	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones].	2.69693e-63
NZ_CP012022.2\|WP_048589315.1\|2122947_2123460_+\|hypothetical-protein	gnl\|CDD\|240308	PTZ00188, PTZ00188, adrenodoxin reductase; Provisional.	0.000640946
NZ_CP012022.2\|WP_048589317.1\|2126378_2127035_+\|DUF1707-domain-containing-protein	gnl\|CDD\|377959	pfam08044, DUF1707, Domain of unknown function (DUF1707). This domain is found in a variety of Actinomycetales proteins. All of the proteins containing this domain are hypothetical and probably membrane bound or associated. Currently, it is unclear to the function of this domain.	2.89083e-16
NZ_CP012022.2\|WP_058093289.1\|2116494_2118171_-\|dipeptide/oligopeptide/nickel-ABC-transporter-permease/ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	9.26447e-78
NZ_CP012022.2\|WP_048589324.1\|2133666_2135376_-\|urease-subunit-alpha	gnl\|CDD\|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0
NZ_CP012022.2\|WP_048589319.1\|2128144_2129212_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.38533e-74
NZ_CP012022.2\|WP_048589309.1\|2113208_2114084_-\|class-C-sortase	gnl\|CDD\|320676	cd05827, Sortase_C, Sortase domain found in class C sortases. Class C sortases are membrane-bound cysteine transpeptidases broadly distributed in Gram-positive bacteria (mainly present in Firmicutes and Actinobacteria). They function as pilin polymerases responsible for the assembly of pili, which are multi-subunit hair-like fibres that extend from the cell surface to promote microbial adhesion and biofilm formation. First, one or more class C sortases form the long thin shaft of the pilus through linking together pilin subunits via isopeptide bonds. The base of the pilus is then anchored to the cell wall by a housekeeping sortase or, in some cases, the class C sortase itself. Depending upon the organism both the number and type of sortase enzymes involved varies, and in some cases, accessory factors appear to be needed. In three-component spaA pilus from Corynebacterium diphtheriae, the prototypical class C sortase (named Cd-SrtA) catalyzes polymerization of the SpaA-type pilus, consisting of the shaft pilin SpaA, tip pilin SpaC and minor pilin SpaB. The pilus shaft is then attached to the cell wall by a housekeeping class E sortase, Cd-SrtF. In the absence of Cd-SrtF, Cd-SrtA attaches the pilus to the cell wall, albeit at a reduced rate. Cd-SrtA can recognize two distinct sorting signals (LPLTG in SpaA and SpaC, and LAFTG in SpaB) and it can employ lysine residues that originate from different proteins (either Lys190 within the pilin motif of SpaA or Lys139 in SpaB). However, Cd-SrtA cannot be able to polymerize the major pilin subunit SpaH, even though it contains LPLTG motif. In two-component pili of prototypical Bacillus cereus, the class C sortase (named Bc-SrtD) cleaves related sorting signals within a major pilin protein BcpA (LPVTG) and a minor tip pilin BcpB (IPNTG), and catalyzes a transpeptidation that joins the threonine residues in each signal to the side-chain of Lys162 in BcpA (located within a pilin motif). Unlike the SpaA pilus in C. diphtheriae, in B. cereus Bc-SrtD is unable to covalently attach the pilus to the cell wall without the help of the housekeeping sortase.	4.79568e-77

>NZ_CP012022.2|WP_048589315.1|2122947_2123460_+|hypothetical-protein
MFSAFRIAVIGANATGLYASDLLLQCSHAIHIDLINESPVPTGISPFSQTPQQLPRRIPDAGFASSIRFIGNIHSSALAETQLEDYYDSVIIADFAEDTDVHNAVLAAISSLSDYSREGKYTKRKDLVEFLSERGIVHTLWADASALLAGRDLDAWRRAVHTAQGAPVCF
>NZ_CP012022.2|WP_048589314.1|2121103_2122708_-|inorganic-phosphate-transporter
MADSAMLTTPSTEDAGSDRWWHLTFGGLLAVTLLVFALWSFGYVGDTANKGILITTILFGVFMAFNIGGNDVANSFGTSVGAGTLTMKQALIVAAIFEVSGAVLAGGEVTDTVKSGIVDLDAIDLSPHHFAFIMMASLLGAAVWLLLATRMGWPVSTTHSIIGGIVGASLVLGFSQGLGGWEMVQWGEFGQIALSWVLSPVLGGLAAWLLFGFIKKHILVYNEGADEQLRQIKADRIELHKSFKASFERLNEIQQLAYTNAMTRDAALIQERDFDPSELESEYYRDLYRINHRRDNLNTHQALENWVPLLAAGGAALIGAMMLFKGLKNLNLHISTLGNVLILGMVSAVVWMAVLIFSRTLKQQELSRATFVIFSWMQVFTASAFAFSHGSNDIANAIGPFSAVLDVLRTDSINGKAAVPTALMITCGVALIAGLWFIGRYVIHTVGSGLTEMHPASGFSAELAAAAVVMGASVLGLPVSSTHILIGAILGIGIVNKAANWRLMKPIAMAWVITLPAAAFVSGVAVFVLNAVWG
>NZ_CP012022.2|WP_048589313.1|2119239_2120880_-|ABC-transporter-substrate-binding-protein
MRRSSSFLALCSKRSGAVLLSMALAGGALAACGDPSHKEASGEEGYPSRLVLADRQAGDGFHPATGYGQTGVSPVYDGLLRPESAGPDRIPNFVPALAAAMPEHNGDATEWTVKLREGVKFSDGSDFDAQDVKASYDMARNIDAGSQVVARYEVIKDVEVKDPHTVVFKLNHPLAEMNSRLLYAIAPSEQLKAGGAITKAELNTKPVGTGAYTLVENRGDEVVFKANENYWGGAPQVKEIVVTTAADDTARAQRVAAGEVDGAAIPPAQVNSVKDKNGIEIVSTKTADWRGISFPKVPELEDTRVRQALNFAVDRQAFVDGTLGGYGTTLETLISPLYGDAHDPSKTFGYDVAKAEKLLDEAGWKKNAAGMREKDGKPFHVTLYYASSDTTRRDIAIEFSSQMKKLGLDFETKAGTWDEIGPALGEAAAVLGGGSAPYDVTIMAYEYLHTRTPSTSKWANPGNYGSEELNKLLDEARSEVDTAKRNKLWQKAQAMYIEDPSALCLLNLEHVYAGKTNKWKKPETLLEPHIHGVTWGPWWRVAEWTK
>NZ_CP012022.2|WP_014801045.1|2118163_2119159_-|ABC-transporter-permease
MLLPGRRDNLDGIGTMVGLRLLIIAFTTVVVTFIMFALAALSPFDPLAHYLGAEYGDYTDDERARIAVSLGVDKPWWQQWLQWWADVLRGDLGWSRVYNKSVVDVISERLPWTVVLSSVGLLLMLLIAAILGVWAARRPGGVVDRAVNAIGVFVAATPSYIYALGAVLFFGVFLHVIPVGGASRIGEVPSLLTVGPYLIAPAIVLAISQLSWPLLTMQQSTLEASQSPAVANARLRGLSERTILVRHVLPLSLMPLITLIGARLGELVVGAVIVETVFSWPGLAQATVESAIAVDFPLLAFTTAATTVVVMLGSLASDISYMIIDPRVSDV
>NZ_CP012022.2|WP_058093289.1|2116494_2118171_-|dipeptide/oligopeptide/nickel-ABC-transporter-permease/ATP-binding-protein
MSKQAKSPVVMHVQKWAKYHRISISVFVGVVLYGLLIPVFFDAGSPSFSKALKPPSSTNLFGTDHFGFDLFVRTAESLRVSLVIGSLSALVATALGVIVGLIAAAVGGRTDRIIMRLNDAVNSIPHLILSVVIVALFRGSLIAIVLSIALTHWSPVARIVRSSVLAVRTSDYVDASYAAGGPFKWVLIRHLAPAAAGQAVVAMIMLMPHAVWHESALSFLGLGIQADEPSLGTLMDLAREDIMRGAWWALVFPAAVLLTTTLSAVSLARKVPEVVIDVDVTETEEQVETDVVAPSDGMEVHNVSVVVHGKDATQQRILKDASLHVEAGSIHGLIGASGSGKTTLGKSIVGIAPQYSKLVGRVSVAGKPLAWGEKDFSKIRGTVVGFVPQSAAQSFTPVRRLGTQLQEIIDRHQGTYSVSDLLRTVHLPEESAEFFPHQLSGGMAQRAAIAAALAGNPTYLIADEPTSALDPQLTSDILALFKEIADSRGVGILIISHDIEDLRESEICDTVSVMRDGEIMETGPADKVLHTPDHEYTRALLAALPSGGLKVTEGLERG
>NZ_CP012022.2|WP_048589311.1|2115836_2116502_-|ATP-binding-cassette-domain-containing-protein
MDNTHNLRASAVTVEFTKNAPVLKDVSIDINPGQMIGLVGLSGSGKTTLARLLAGKMRPTSGKVLIDSAEVSTQRGHRNPDIATINQSPRDACSPRWKLRDIIAEPLRIAGKLDEKSIAERVDECADEALVDATLLDRLPHQVSDGQLQRACIARALAQAPRFLICDEPTSMLDPLATAAVVSLLRRQADNGVGVLLISHDHRLLAACVDTVLEMDQLKQM
>NZ_CP012022.2|WP_048589310.1|2114431_2115793_+|AI-2E-family-transporter
MDMHKNPNSQPPGTASDRDISDLLNSAVEESEPFVPPANEAPRKDRAIILGADARWASGWALRFIIVVIASVMAWRGLATIWQGLLPVILALLLCTVLWPPVRWLRSKKVPPATAVLIVAIGFFGAIGSIFAAMAPSVSSQSKDLVDRANEGVQRALHWAEHGPLNLDTSQVDGYIQNVTQALQEHSRNIANGVFSGLTTASSILITIILMLILSFFFLKDGTRFLPMVRRVAGPNLGWHLTEVLTRIWNVLAGFIRAQAIVSLVDAVLIGIGLLILKVPLALVLAVLTFFGGFIPIVGAFTAGALAVVIALVSNGVSNAIFALILIIAVQQIEGHILQPVLQSRAMNLHAAVVLLSVTIGSALFSVVGAFLAVPVAATLAVLIRYHSELVALRAGEITLDEIELATAEEATPSINGEQAWGNLKDQLTKLSLRKTSNVVIKKEEAPSNPADD
>NZ_CP012022.2|WP_048589309.1|2113208_2114084_-|class-C-sortase
MPFMKENLSKTLNKPVMISLVLVIVGVITLLYPVAAAYMHNASHAQEAQKYIDVQKGVSDADRERWIAQAQSYNERLARIPILDPWLSRVSKDSGLYREYMAQLNAPGTDDAVMSVVSIPSITTTLPVFHGTDDEALDKGLGHIYGSSLPVGGENTHAVITGHSGLSEATMFDNLEKVQVGDMVYVDTVGKVLTYKVTDTEVVLPSEIESLRAQKGKDLLTLITCTPYAINTHRLLVHAERVETSEENLPQSAVRWEGWMAWRILAALAIVAVVLVIYLRRRAGNKENERV
>NZ_CP012022.2|WP_048589308.1|2112418_2113204_-|hypothetical-protein
MVKQNKLARIRLAVVAVIGTAVLFSSPAAFARPAVSVDSVQAATIDPTRTASLSIEFKNSPTARDTLSRIPVRIARIDGIDLTTQEGWLAASKLSVAEALKQPESQSWQAKTDSSGRVRFDALPIGLYKVQPVKGSDRGFEPFVVPLPSSAETGEWNYDLLVHPKPKHKEESEPTVPWWDPTIPPLPSKTPQPPQPATTSPATPGPSPDKPGKDDKQKPNTSPLARTGASVIGVALLGLLLAALGFGAVMWNKKNNRGDDE
>NZ_CP012022.2|WP_087907614.1|2106818_2112416_-|VWA-domain-containing-protein
MIVTLKKQLRWLTRHMLAVAAVLAIMVAALAFPLSEEPAAQAEQVAVQPPLVRPAPAQPAAQNPDLDLNKCGATVAFVVDLSNSLSQADLDNQKKTLREMVKSLEGAPYVFSLYTFASAAPAYGENNQNLKSMSLRDPEDVKKLRDRIDSLFLPGNGFGGTNWEQGLRQVADEIEAGAHYDTVYFITDGKPTFDSNGKNYQGNTTEQSEIDNAVKQKERFVKSKTQLIPIGVGSAIQDRTPQEIRALRRNDWGYYPYWQIVKHHTSQEMLKMIASDPNKVIISPDYATLPSKLQSNFVTGCLLVNKEIVDGNGTLIEPGANWHFDVEGGTADKKELVTNARGVASAAVSDFNEGNPKVKVTERQQEDFQLLTEGDKAVTCQAFQAGGTPQKLTTTAVTDGVELTLDPAKIISCTFSNVPKVPVEIGKDVVTPNSVLSPTVKGRTFDLNYTCTYKGREVAKKEEKGLISGERRQIGKLPLGTKCVVEESQPQVDQKLYTLKTTWATDNVESASGNDRKIEFVVGKKAYEDKGRVSVVATNTYEPVMRTIKLSKQIANRNNIPASLLPKNYPVKYTCRYIPDRSQRPENGGKDQPLYVANGVAIVPLDGEATIGPLPVGTECAFIEEGTPENPIAIDGYNLDPSWQSNVCVNAGEDAASGLKKCQGNYFWLNPDDSTDPQAKAVNNYEPERGSIIIEKKVGGKDSDLGRENEFIFDAVCRREGLEVFKKEGIKVAGGQSVRVDDIPVASTCTVHERDVTVENATVKKAADAQVVVGPDNEEPRTASMTNEFVRDQGPITIKKSVDVSQVLDDTKHAELKAGPFKVKAQCVVPMEHSPRSVEVTLTDGETQTLGNFPVGTECSLTEDYKVPDGVELEKDFSTNVATVKSKEGTSVDLKNVFSTPNGDLTISKKVAVLKEDVEDLDAYVPKTFNFDLTCTDGTNKSFSLDAEAEEVISGIKVGAKCTLTEQDTQHSQEVIESTSMEGVDQSVTGKAMTFTIPEVGQAATIDVRNEYKPAMAKLTLNKKVNATYQGNGQQVPEDIISGLFADTKFQFSYTCSRGGKELLQSTAQIGRGESIEVEVPVNASCSFTESTVEIDGLEGPTLSLEGAGRLDGEKSDTISVDKIAANTTGTVMNNYKVKTGSFNLRKKVGGDGITEIDKDRKFNLSYTCTYRGKVLREGKMSIARFEPGSEHKVDNLPIGTECQVSEDLDNAQLPNHKLALTWAVTEDQEGNGTETSCTLAENCESTPGQNSAVIKISETENSSGAEPNFQGTLVLWNSYTADRLKVQVTKQLTGDGPALASDEDFVFNLVCKDPRSERAITAQRTIKGAGNGLFNVADTQEQTPVEIPVGWSCLITEEQINRYDADVNVSFEGAKLETPLTDTAGATGTFKIAGEPNSTQNVTVKNDYVRKRAQLRVATKYVGNQQGNVNEYLTNKETFGVSWRCEDQLTNQVYEGSLRVPADGKLIEILDKDGKRLPVSVECELTEDTSDKVPAEFANSVQSSHRVYASRNDEVFLDKPGSVTIKPIDLETDNVTDVVFENSYWMNTMAFSVQKHLEGPEGALGENPQFHFTYRCELPLLPTQPVPEAFRAGATSPTGSQTVKGTFDIGHGQSWVAPGAPTGTRCWISEELTEEQRALLASKGLRLEQSTTQLFEATPTEQADESLEQQIAKAKRTPIAPNGEVELNAEQGGDVIYINSLYRTEGSILIEKVDAKGEPLKGSRFSIFRAEGDRPAGEPLFTDIAPESQKPISLAPGSYYLVETTPGEGAQLLPQSWRFNVTPTGEQSGDLRFTLEPQASDSGLITVKRKDDNDPTSAWVIQVANVKTGELPLTGRGGRKLFTIIPVVLLLVAGGIYAWRRRNE
>NZ_CP012022.2|WP_048589317.1|2126378_2127035_+|DUF1707-domain-containing-protein
MTNPYQPDYRIGDAERAQAMDDLGVHFSAGRLSFEEYDERLKQVTQAVTRSDISLLFDDLPAARSPKVNDPSDFLPTTRVPEAHFPDTYSGDEIDNAYSTGRNIRGGILGLTGVTAVTLTTLTGTGAWIMLVPAIFILLDVMKLGPESWHAPSRNKIDRQRMKQARLLQQQQVFAIETHNAQQRALARAERKRKQEEFNSIATELATDALKRFRGKNK
>NZ_CP012022.2|WP_048589318.1|2127044_2127356_-|winged-helix-turn-helix-transcriptional-regulator
MYDLLEQADDWSNDFKLMGDRTRLRILVVLRYAGPRATTVTEIAETAGVRVPTASGALRAMEHMGAIKGERFGREVRYSLVDERIHGILHDIGMRHGKDKDRD
>NZ_CP012022.2|WP_048589319.1|2128144_2129212_-|iron-ABC-transporter-permease
MDLDSRLTTRTVAPTTDSAPRKRRFRPAFPLVVMGGVILLIVLSVGSVFIGAASLSWDEVMGAMGFAGYDTPSLLRQSILFELRVPRILMGIVVGAGLAVAGACLQTVTHNPLAEPYLLGISGGASVGAVVVLVIGTQGILGLTAGAALGGLGSFLVLLMLLRGSGFQSQQVVLAGVLVGQFAQAVTFLIMMGKGDADSIQAVMAWLMGALGASRQEGLLVTFIVCIAAIVVLWALSRHLDTLRLGDATAHTMGVPVVLTRGAVLVIVALMTSATVASVGAIGFVGLIVPHAVRLVVGSAHARVIPVSALVGAILLVVADAIARSLFKGQELPVGIITALIGVPIFFLLWKKGKK
>NZ_CP012022.2|WP_048589320.1|2129230_2130241_-|ABC-transporter-substrate-binding-protein
MISFFSCRRRMLVSTSVVVAAGLTLSACSNTSDKKTDSSANASQAVSVENCGVKVSLSAPAHRLVSVEQGTTETLLAFDAQKDIVGVGHTKDHYWKRYEDRAKNLPVISDSVPNAEAIRGVDPDLVLSPFASVWTESGSGTREEYSKLGVGTFTTNVECAKPEEDPYMVLERDYEQLGVLLGKESRAKELIEEQRAAVKAAKDANVNSHKSVGYLYSIFDNAPYVAGNYGIPSAISAATGSTNVFAGIEEAWPQISWEAFADADPDVIVLVDLPGRGSPGDLATEKIAALKSNPATRNMKAVQGEKFIVVPGAGLSPGARSIEPLEIVGKKLAEMK
>NZ_CP012022.2|WP_048589321.1|2130839_2131718_-|urease-accessory-protein-UreD
MWSVTKGIFEHDPPHEEMGVLELGVGVSGGKSIAKTQYHTRALKIVRPHYLDDSGQVYYIVVNPGGGYVGGDAYRLRFEVESGASVLLTDQSAAKVYRTPDDFVVQNIEIKVDAGGVLEYVPDQLILYRDADFRQQITADVHPEGSLFISDVITPGWSPEGEKFLYRQAHIRSVVRMNGEVVLVDNLRINPLEAEFAQDADLMMGGKTHVATAICFDPSIDSDFIQDLKECVSAHSAENPDVIAAISECDRPGFVLRGLGNRTEELMELILDVAHIVRSKTRGQGPINLRQY
>NZ_CP012022.2|WP_013242776.1|2131718_2132333_-|urease-accessory-protein-UreG
MSVIKIGVGGPVGSGKTALIERITRALDGKISMAAITNDIYTTEDAKILAREGLLPEDRIIGVETGGCPHTAIREDTSMNDAAFEELVRRHPDLELVFMESGGDNLSATFSPELVDFSIYIIDVAQGEKIPRKAGQGMIKSDLFVINKTDLAPYVGADLKVMEDDSKVFRGDKPFVLTNLKTDEGLDKVIDWIRHDVLMLDLAD
>NZ_CP012022.2|WP_048589322.1|2132356_2133076_-|urease-accessory-protein-UreF
MQSIATSARTELVIWHLTDSALPTGGFAHSAGLETFIQSGEVHDPDSYKHWLHGYLRQASFAEALAVRFAAELAQSGLDCAEAQPLLKELDQLVHACQTPKQVRTSMNSMGKRMSKVAATISPDQPMVAEYCRAVAAGEMRGNPAIAAGLVLGAEGVSPERAVMAYLMQMANSMTQNAIRAIPLGQDAGQRVLVSVYQAVMESAEMTMSHGVADLGVVAPRLEVAQMQHEMLRSRMFMS
>NZ_CP012022.2|WP_048589323.1|2133056_2133533_-|urease-accessory-protein-UreE
MIITEIQGNLNHLVSEERDALELDAVIFDNETRLKRVQRVTTESGAEYALRLGNELREIKDGDILAKEDNKVIVARIAATDVLVITPRDIREALAVAHTLGNRHLQAQFFDQDSVFGKAAMVVRFDHTVEHYLEHAGVEYTRGDYVMPEAFRHAEHSH
>NZ_CP012022.2|WP_048589324.1|2133666_2135376_-|urease-subunit-alpha
MSFEMSRRQYAELNGPTTGDGIRLADTELIAVVEKDLTQYGDEVSFGGGKVIRDGMGQNSRVEADQVPDLVITNTIIVDCTGIYSADIAVKDGKIMKIGKAGNPDIMDNIDIIVGVGTEVIGGEGKIVTAGAIDTHIHFISPEQVEAALDNGTTTLIGGGTGPVDSTNATTVTAGAANITKMIEASRDFSVNVGFLGKGHASNPERLREQIRAGAIGLKIHEDWGATANTIDNALTVADEMDVQVAIHTDTLNEGGFADNTIAAFKDRVIHTFHTEGAGGGHAPDILKVAGLPNVLPASTNPTLPFTVNTMDEHLDMIMVCHHLNADLPEDIAFADSRIRKETIAAEDVLHDMGVLAITSSDSQAMGRVGEVVLRTWQVAHRMKQQRGPLEGDTVNNDNERIKRYIAKYTINPAIAAGVADTIGSVEEGKLADLVVWDPAYFGVKPSIVLKSGIIARSIMGDANASIPTPQPRTMRYSFGARGAAAGRTSVTFLPTAAFEAGIPEKLGIDRKFVEAKNMREISKADLKYNNATPDIKVDPETYELTVDGKKVTSEAATELPMTQRYFLF
>NZ_CP012022.2|WP_048589325.1|2135443_2135755_-|urease-subunit-beta
MIPGEYFISDAAPIIMNEGRESITIVVTNKGDRPVQVGSHFHFAEANSELEFDREAAMGKRLDIQAGTAVRLEPGDSRTVELIDFAGTREVYGFNNKVNGKLD

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012022_2	2.2\|1837627\|30\|NZ_CP012022\|PILER-CR	1837627-1837656	30	NZ_CP047963	Aeromonas media strain MC64 plasmid pMC64A, complete sequence	122692-122721	8	0.733
NZ_CP012022_1	1.2\|25774\|32\|NZ_CP012022\|PILER-CR,CRISPRCasFinder,CRT	25774-25805	32	NZ_CP014851	Bacillus thuringiensis strain HD12 plasmid pHD120112, complete sequence	73328-73359	9	0.719
NZ_CP012022_1	1.2\|25774\|32\|NZ_CP012022\|PILER-CR,CRISPRCasFinder,CRT	25774-25805	32	CP002509	Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26, complete sequence	179787-179818	9	0.719
NZ_CP012022_1	1.2\|25774\|32\|NZ_CP012022\|PILER-CR,CRISPRCasFinder,CRT	25774-25805	32	CP002510	Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB28, complete sequence	127894-127925	9	0.719
NZ_CP012022_1	1.2\|25774\|32\|NZ_CP012022\|PILER-CR,CRISPRCasFinder,CRT	25774-25805	32	NC_025830	Escherichia phage Av-05, complete genome	9358-9389	11	0.656

1. spacer 2.2|1837627|30|NZ_CP012022|PILER-CR matches to NZ_CP047963 (Aeromonas media strain MC64 plasmid pMC64A, complete sequence) position: , mismatch: 8, identity: 0.733

cacccagacttcacgtattcgtgatggtgc	CRISPR spacer
agttcggtcttcacgtattcatgatggtgg	Protospacer
 ...*.* ************.********

2. spacer 1.2|25774|32|NZ_CP012022|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014851 (Bacillus thuringiensis strain HD12 plasmid pHD120112, complete sequence) position: , mismatch: 9, identity: 0.719

ccgcctggcgcaaagataaagacggcaatacc	CRISPR spacer
atttgtcccgtaaagataatgacggcaatacc	Protospacer
 . . *  **.******** ************

3. spacer 1.2|25774|32|NZ_CP012022|PILER-CR,CRISPRCasFinder,CRT matches to CP002509 (Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26, complete sequence) position: , mismatch: 9, identity: 0.719

ccgcctggcgcaaagataaagacggcaatacc	CRISPR spacer
atttgtcccgtaaagataatgacggcaatacc	Protospacer
 . . *  **.******** ************

4. spacer 1.2|25774|32|NZ_CP012022|PILER-CR,CRISPRCasFinder,CRT matches to CP002510 (Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB28, complete sequence) position: , mismatch: 9, identity: 0.719

ccgcctggcgcaaagataaagacggcaatacc	CRISPR spacer
atttgtcccgtaaagataatgacggcaatacc	Protospacer
 . . *  **.******** ************

5. spacer 1.2|25774|32|NZ_CP012022|PILER-CR,CRISPRCasFinder,CRT matches to NC_025830 (Escherichia phage Av-05, complete genome) position: , mismatch: 11, identity: 0.656

ccgcctggcgcaaagataaagacggcaatacc	CRISPR spacer
tgaaaaaacgcaaagatgaagacggtaatact	Protospacer
. .   ..*********.*******.*****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1753692 : 1830810

Agrobacterium_phage(16.67%)

tRNA,protease,bacteriocin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048589491.1\|1753692_1756428_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	4.1e-139	38.8
WP_013242455.1\|1756593_1757574_-	malate dehydrogenase	NA	NA	NA	NA
WP_013242456.1\|1758175_1758934_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_048589167.1\|1758991_1760278_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	8.7e-132	55.8
WP_048589168.1\|1760438_1763243_-	aminodeoxychorismate synthase component I	A0A0B5J984	Pandoravirus	5.1e-84	34.0
WP_013242459.1\|1763319_1763949_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	1.4e-37	43.5
WP_048589169.1\|1763964_1764564_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	3.0e-42	48.3
WP_048589170.1\|1764774_1766127_-	trigger factor	NA	NA	NA	NA
WP_014300878.1\|1766913_1767156_+	hypothetical protein	A0A1W6JRB8	Corynebacterium_phage	3.9e-09	48.4
WP_013242463.1\|1767292_1768069_+	hypothetical protein	NA	NA	NA	NA
WP_048589171.1\|1768155_1769166_-	pirin family protein	NA	NA	NA	NA
WP_013242465.1\|1769282_1769756_-	ribose-5-phosphate isomerase	NA	NA	NA	NA
WP_014367467.1\|1769822_1770443_-	DSBA oxidoreductase	NA	NA	NA	NA
WP_048589172.1\|1770776_1773392_+	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	1.7e-41	29.7
WP_048589173.1\|1773813_1774488_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_013242471.1\|1774510_1774903_+	globin	NA	NA	NA	NA
WP_048589174.1\|1774914_1775811_+	DMT family transporter	NA	NA	NA	NA
WP_048589175.1\|1775814_1776423_-	hypothetical protein	NA	NA	NA	NA
WP_013242474.1\|1776428_1776857_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_048589176.1\|1777064_1778735_-	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	1.0e-47	27.8
WP_013242476.1\|1778924_1779485_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_048589177.1\|1780013_1781768_+	hypothetical protein	NA	NA	NA	NA
WP_048589178.1\|1781764_1783303_+	YcaO-like family protein	NA	NA	NA	NA
WP_048589179.1\|1783330_1784809_+	nitroreductase	NA	NA	NA	NA
WP_048589180.1\|1784805_1787409_+	lantibiotic dehydratase	NA	NA	NA	NA
WP_048589181.1\|1787408_1788422_+	hypothetical protein	NA	NA	NA	NA
WP_048589182.1\|1788418_1789399_+	hypothetical protein	NA	NA	NA	NA
WP_145951892.1\|1789437_1789611_+\|bacteriocin	thiazolylpeptide-type bacteriocin	NA	NA	NA	NA
WP_048589183.1\|1789684_1791136_+	YcaO-like family protein	NA	NA	NA	NA
WP_014367484.1\|1791157_1791916_-	permease	NA	NA	NA	NA
WP_048589184.1\|1791912_1792836_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	4.2e-19	26.1
WP_048589185.1\|1792926_1794972_-	bifunctional copper resistance protein CopD/cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_048589186.1\|1795564_1797850_+	carbon starvation protein A	NA	NA	NA	NA
WP_014401336.1\|1797869_1798070_+	YbdD/YjiX family protein	NA	NA	NA	NA
WP_048589187.1\|1798400_1800227_-	S8 family peptidase	A0A1B0T6A2	Bacillus_phage	8.9e-29	31.6
WP_048589188.1\|1800502_1801498_+	oxidoreductase	NA	NA	NA	NA
WP_013242491.1\|1801625_1802429_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_080577986.1\|1802494_1803154_+	oligoribonuclease	M4M9I5	Vibrio_phage	8.4e-22	35.0
WP_013242493.1\|1803333_1804161_+	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_048589189.1\|1804214_1805405_-	L,D-transpeptidase	NA	NA	NA	NA
WP_048589190.1\|1806240_1807239_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_048589191.1\|1807438_1807993_+	isochorismatase family protein	A0A2K9L2K0	Tupanvirus	9.0e-17	32.6
WP_014800825.1\|1808001_1808346_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_013242498.1\|1808467_1808743_-	DUF3618 domain-containing protein	NA	NA	NA	NA
WP_013242499.1\|1808831_1809311_+	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_013242500.1\|1809348_1810002_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_048589192.1\|1810014_1810404_-	holo-ACP synthase	NA	NA	NA	NA
WP_013242503.1\|1819856_1820162_-	hypothetical protein	NA	NA	NA	NA
WP_048589194.1\|1820323_1821439_+	two-component sensor histidine kinase	NA	NA	NA	NA
WP_048589195.1\|1821435_1822062_+	response regulator transcription factor	NA	NA	NA	NA
WP_048589196.1\|1822105_1823137_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_014524035.1\|1823317_1824076_-	hypothetical protein	NA	NA	NA	NA
WP_013242508.1\|1824575_1825238_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_048589197.1\|1825828_1826275_+	hypothetical protein	NA	NA	NA	NA
WP_048589198.1\|1826362_1826722_+	DUF3817 domain-containing protein	NA	NA	NA	NA
WP_048589199.1\|1826791_1827415_-	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	NA	NA	NA	NA
WP_032802570.1\|1827411_1828146_-	ribonuclease PH	NA	NA	NA	NA
WP_013242513.1\|1828184_1828952_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_048589200.1\|1829024_1829918_-	glutamate racemase	NA	NA	NA	NA
WP_048589201.1\|1829991_1830810_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA

DBSCAN-SWA_2

1979205 : 1987666

Pandoravirus(33.33%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048589253.1\|1979205_1980954_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	2.2e-61	31.5
WP_013242638.1\|1980931_1981600_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
WP_014300952.1\|1981607_1981994_-	hypothetical protein	NA	NA	NA	NA
WP_014300953.1\|1981990_1982506_-	hypothetical protein	NA	NA	NA	NA
WP_048589254.1\|1982516_1982963_-	DUF3180 domain-containing protein	NA	NA	NA	NA
WP_014300954.1\|1982959_1983415_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	S4W084	Pandoravirus	3.9e-10	34.5
WP_013242643.1\|1983416_1983758_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_048589255.1\|1983744_1984527_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	1.4e-20	32.5
WP_014367628.1\|1984528_1985092_-	GTP cyclohydrolase I FolE	A0A1W7AF02	Streptococcus_virus	2.6e-48	57.8
WP_014523609.1\|1985084_1987088_-	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	E5EQU5	Bathycoccus_sp._RCC1105_virus	7.8e-111	50.3
WP_014300955.1\|1987084_1987666_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	3.0e-15	31.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012022

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection