CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
NZ_CP012008	Acinetobacter baumannii strain Ab04-mff plasmid pAB04-2, complete sequence	0 crisprs	NA	1
NZ_CP012007	Acinetobacter baumannii strain Ab04-mff plasmid pAB04-1, complete sequence	0 crisprs	NA	2
NZ_CP012006	Acinetobacter baumannii strain Ab04-mff chromosome, complete genome	3 crisprs	cas3,DEDDh,WYL,csa3,PD-DExK	8

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

41742 : 75419

uncultured_Caudovirales_phage(40.0%)

transposase,integrase

attL 36450:36471|attR 64414:64435

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
36450:36471	attL	NA	NA	NA	NA
WP_087486612.1\|41742_42833_-\|transposase	IS4 family transposase ISAba1	NA	NA	NA	NA
WP_001046004.1\|42938_43760_+	carbapenem-hydrolyzing class D beta-lactamase OXA-23	NA	NA	NA	NA
WP_001992510.1\|44424_44979_-	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_000262332.1\|44986_45319_-	hypothetical protein	NA	NA	NA	NA
WP_085947913.1\|45420_46510_+\|transposase	IS4 family transposase ISAba1	NA	NA	NA	NA
WP_001277980.1\|46514_47981_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.3e-213	79.6
WP_000034564.1\|47993_48845_+	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	8.2e-70	45.9
WP_001095006.1\|48912_49212_+	hypothetical protein	NA	NA	NA	NA
WP_000529372.1\|49284_49656_+	hypothetical protein	NA	NA	NA	NA
WP_002017214.1\|50030_51461_-	hypothetical protein	NA	NA	NA	NA
WP_000081835.1\|51453_52569_-	TniQ family protein	NA	NA	NA	NA
WP_000417085.1\|52598_53519_-	TniB family NTP-binding protein	NA	NA	NA	NA
WP_000573060.1\|53523_55434_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_000736399.1\|55434_56145_-\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA
WP_002001525.1\|56269_56437_+	hypothetical protein	NA	NA	NA	NA
WP_000261890.1\|56490_56916_-	hypothetical protein	NA	NA	NA	NA
WP_031943508.1\|57006_60282_-	conjugative relaxase	NA	NA	NA	NA
WP_000644960.1\|60293_62453_-	type IV secretion system DNA-binding domain-containing protein	NA	NA	NA	NA
WP_000192272.1\|62457_62928_-	hypothetical protein	NA	NA	NA	NA
WP_031943507.1\|63505_63835_+	hypothetical protein	NA	NA	NA	NA
WP_000560244.1\|63864_64059_-	hypothetical protein	NA	NA	NA	NA
WP_000597531.1\|64074_64407_-	hypothetical protein	NA	NA	NA	NA
WP_000270931.1\|64551_64836_-	hypothetical protein	NA	NA	NA	NA
64414:64435	attR	NA	NA	NA	NA
WP_000758689.1\|64981_65479_-	molecular chaperone DnaJ	A0A0S2MWN4	Cellulophaga_phage	6.4e-06	27.4
WP_000708714.1\|65514_65829_-	hypothetical protein	NA	NA	NA	NA
WP_001053127.1\|66884_67643_-	hypothetical protein	NA	NA	NA	NA
WP_000654348.1\|67709_68093_-	hypothetical protein	NA	NA	NA	NA
WP_000873188.1\|68231_68930_-	hypothetical protein	NA	NA	NA	NA
WP_000373385.1\|68996_69179_-	hypothetical protein	NA	NA	NA	NA
WP_000710385.1\|69227_69794_-	hypothetical protein	NA	NA	NA	NA
WP_000312250.1\|69994_70354_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_001096429.1\|70353_70653_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_049592568.1\|71190_71475_-	hypothetical protein	NA	NA	NA	NA
WP_079454613.1\|71539_72565_+\|transposase	IS30-like element ISAba125 family transposase	W5R8L2	Staphylococcus_phage	1.2e-51	38.1
WP_000790084.1\|72866_73421_-	hypothetical protein	NA	NA	NA	NA
WP_001043201.1\|73440_73659_-	hypothetical protein	NA	NA	NA	NA
WP_000701003.1\|73698_74328_-	hypothetical protein	NA	NA	NA	NA
WP_010326927.1\|74393_75419_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.1e-51	37.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP012007

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

58658 : 101308

Escherichia_phage(21.43%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067790.1\|58658_59363_-\|transposase	IS6-like element IS1008 family transposase	A0A077SL39	Escherichia_phage	5.1e-118	84.5
WP_000644490.1\|59491_59932_-	hypothetical protein	NA	NA	NA	NA
WP_001046277.1\|60157_60409_+	hypothetical protein	NA	NA	NA	NA
WP_001024681.1\|60431_60779_+	hypothetical protein	NA	NA	NA	NA
WP_045544691.1\|60793_62644_-	hypothetical protein	A0A193GYG9	Enterobacter_phage	1.3e-08	26.1
WP_000504197.1\|62764_63190_-	hypothetical protein	NA	NA	NA	NA
WP_001090439.1\|63269_63764_-	hypothetical protein	NA	NA	NA	NA
WP_000913724.1\|64107_64839_+	hypothetical protein	NA	NA	NA	NA
WP_000941930.1\|64825_65653_+	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_000420425.1\|65633_65963_+	DUF1456 family protein	NA	NA	NA	NA
WP_002015113.1\|66006_66222_+	hypothetical protein	NA	NA	NA	NA
WP_000038505.1\|66262_66598_+	hypothetical protein	NA	NA	NA	NA
WP_002015149.1\|66629_67541_-	hypothetical protein	NA	NA	NA	NA
WP_001101323.1\|67856_68960_-	hypothetical protein	NA	NA	NA	NA
WP_000131185.1\|69133_71395_+	type I DNA topoisomerase	E3T4K4	Cafeteria_roenbergensis_virus	4.0e-63	32.5
WP_000386247.1\|71847_72252_-	hypothetical protein	NA	NA	NA	NA
WP_001144971.1\|72461_74249_+	hypothetical protein	NA	NA	NA	NA
WP_001082319.1\|74631_75435_+	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_000480968.1\|75434_76271_+	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_000743213.1\|76390_76615_+	hypothetical protein	NA	NA	NA	NA
WP_001120888.1\|76825_78319_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_101458100.1\|78482_78920_+	bifunctional nuclease family protein	NA	NA	NA	NA
WP_049581831.1\|78923_79748_+	thymidylate synthase	A0A2R4A1R4	Microbacterium_phage	1.8e-98	63.9
WP_049581834.1\|79747_80242_+	dihydrofolate reductase	A0A076GDN3	Bacillus_phage	5.3e-29	37.1
WP_001120888.1\|82153_83647_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_001445143.1\|83677_83929_+	hypothetical protein	NA	NA	NA	NA
WP_000251875.1\|83822_84125_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_001043260.1\|84211_85027_-	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
WP_000338945.1\|85333_85645_+	hypothetical protein	NA	NA	NA	NA
WP_014342215.1\|85659_85791_-	hypothetical protein	NA	NA	NA	NA
WP_045544682.1\|85818_86604_+	ParA family protein	A0A1X9IGI7	Lactococcus_phage	2.1e-11	26.8
WP_001207227.1\|86607_87789_+	ParB/RepB/Spo0J family partition protein	I3NLC2	Bifidobacterium_phage	2.4e-11	28.7
WP_000703827.1\|87837_88110_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000074431.1\|88162_88798_-	N-6 DNA methylase	NA	NA	NA	NA
WP_000939033.1\|88889_89033_-	hypothetical protein	NA	NA	NA	NA
WP_001125905.1\|89351_89729_+	hypothetical protein	A0A2H4P7P5	Pseudomonas_phage	2.2e-22	49.6
WP_014342216.1\|89871_89991_-	hypothetical protein	NA	NA	NA	NA
WP_000344151.1\|89977_90652_+	thymidylate kinase	NA	NA	NA	NA
WP_005507681.1\|90719_91151_+	hypothetical protein	NA	NA	NA	NA
WP_002210541.1\|91156_91468_+	hypothetical protein	NA	NA	NA	NA
WP_000647189.1\|91476_91977_+	hypothetical protein	I3UMJ0	Colwellia_phage	1.7e-19	43.3
WP_001067855.1\|93402_94107_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000237816.1\|94340_94793_-	NAD(+)--rifampin ADP-ribosyltransferase Arr-2	NA	NA	NA	NA
WP_001067855.1\|95815_96520_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_012300772.1\|96730_97990_+	chloramphenicol efflux MFS transporter CmlA5	S4TR35	Salmonella_phage	1.7e-26	31.7
WP_000679427.1\|98181_98529_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|98522_99362_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000050481.1\|99766_101308_+\|transposase	IS91 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

105717 : 131945

Escherichia_phage(33.33%)

transposase,integrase

attL 95020:95033|attR 132166:132179

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
95020:95033	attL	NA	NA	NA	NA
WP_000050481.1\|105717_107259_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_001206290.1\|108544_109753_+\|transposase	IS4-like element IS10A family transposase	Q9E8P4	Bluetongue_virus	3.1e-171	71.4
WP_000359986.1\|109994_110768_+	ArmA family 16S rRNA (guanine(1405)-N(7))-methyltransferase	NA	NA	NA	NA
WP_077252464.1\|110748_111030_-	hypothetical protein	NA	NA	NA	NA
WP_002026779.1\|111249_111435_-	hypothetical protein	NA	NA	NA	NA
WP_002001451.1\|111483_112668_+\|transposase	IS4-like element ISEc29 family transposase	A0A0F7LAS3	uncultured_marine_virus	4.5e-50	35.4
WP_000052512.1\|113066_114542_+	ABC-F type ribosomal protection protein Msr(E)	A0A1B0RXA0	Streptococcus_phage	2.3e-160	59.0
WP_000155092.1\|114597_115482_+	Mph(E) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_004896925.1\|115840_116383_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|117267_117972_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001550559.1\|118005_118497_-	hypothetical protein	NA	NA	NA	NA
WP_001366550.1\|118603_119341_+	recombinase family protein	NA	NA	NA	NA
WP_000743213.1\|119337_119562_+	hypothetical protein	NA	NA	NA	NA
WP_001120888.1\|119772_121266_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000512977.1\|121503_121908_+	hypothetical protein	NA	NA	NA	NA
WP_000088605.1\|121885_122509_-	tetracycline resistance transcriptional repressor TetR(B)	NA	NA	NA	NA
WP_001089072.1\|122590_123796_+	tetracycline efflux MFS transporter Tet(B)	NA	NA	NA	NA
WP_071543477.1\|123834_124128_+	hypothetical protein	NA	NA	NA	NA
WP_000251875.1\|124021_124324_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_001043260.1\|124410_125226_-	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
WP_085940413.1\|125318_126408_+\|transposase	IS4 family transposase ISAba1	NA	NA	NA	NA
WP_000573066.1\|126830_128741_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_049592566.1\|128741_129452_-\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA
WP_000168733.1\|129763_130033_-	hypothetical protein	NA	NA	NA	NA
WP_000798673.1\|130086_130443_-	hypothetical protein	NA	NA	NA	NA
WP_001006517.1\|130488_130806_-	hypothetical protein	NA	NA	NA	NA
WP_000886982.1\|131012_131945_-\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	7.5e-16	36.2
132166:132179	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP012006

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012006_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012006_1

675794-675878

Orphan

Consensus_repeat	Method
TTTTAACTTTGGCGCAAGACAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012006_1

>merge|NZ_CP012006|1|675794-675878|CRISPRCasFinder
TTTTAACTTTGGCGCAAGACAAGCAGTGAAACTGCGCGTAGAGTAAAGAAGATTGATAATCTTTTAATTTTGGCGCAAGACAAGC

>NZ_CP012006|1|1|675794-675878|CRISPRCasFinder
TTTTAACTTTGGCGCAAGACAAGC	AGTGAAACTGCGCGTAGAGTAAAGAAGATTGATAATC
TTTTAATTTTGGCGCAAGACAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012006.1\|WP_001198164.1\|677518_678304_-\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
NZ_CP012006.1\|WP_001017534.1\|674406_675315_-\|DUF1853-family-protein	unknown	unknown	gnl\|CDD\|378094
NZ_CP012006.1\|WP_000101096.1\|664654_665017_+\|response-regulator	unknown	unknown	gnl\|CDD\|381093
NZ_CP012006.1\|WP_001005337.1\|687195_688671_+\|alanine:cation-symporter-family-protein	unknown	unknown	gnl\|CDD\|376500
NZ_CP012006.1\|WP_034129408.1\|684112_685327_+\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_CP012006.1\|WP_001984830.1\|681810_683985_-\|TIGR01666-family-membrane-protein	unknown	unknown	gnl\|CDD\|130727
NZ_CP012006.1\|WP_000077301.1\|675938_676442_+\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|341130
NZ_CP012006.1\|WP_001016573.1\|672902_674039_-\|succinyl-diaminopimelate-desuccinylase	unknown	unknown	gnl\|CDD\|237265
NZ_CP012006.1\|WP_000389061.1\|664247_664631_+\|response-regulator	unknown	unknown	gnl\|CDD\|381093
NZ_CP012006.1\|WP_001259501.1\|675419_675788_+\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291
NZ_CP012006.1\|WP_001984826.1\|674164_674308_-\|entericidin-A/B-family-lipoprotein	unknown	unknown	gnl\|CDD\|227797
NZ_CP012006.1\|WP_000473032.1\|678430_680977_-\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|99797
NZ_CP012006.1\|WP_034129410.1\|665077_665614_+\|purine-binding-chemotaxis-protein-CheW	unknown	unknown	gnl\|CDD\|223905
NZ_CP012006.1\|WP_002010643.1\|686569_686773_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012006.1\|WP_000490937.1\|686955_687096_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012006.1\|WP_034129409.1\|665660_667739_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NZ_CP012006.1\|WP_005119701.1\|667885_672406_+\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|223716
NZ_CP012006.1\|WP_015451615.1\|672438_672867_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012006.1\|WP_001047593.1\|685354_686059_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380313
NZ_CP012006.1\|WP_000125649.1\|681134_681710_-\|SdpI-family-protein	unknown	unknown	gnl\|CDD\|379303

Protein	Function_ID	Function_description	E-value
NZ_CP012006.1\|WP_001198164.1\|677518_678304_-\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	1.40229e-39
NZ_CP012006.1\|WP_001017534.1\|674406_675315_-\|DUF1853-family-protein	gnl\|CDD\|378094	pfam08907, DUF1853, Domain of unknown function (DUF1853). This family of proteins are functionally uncharacterized.	5.07662e-40
NZ_CP012006.1\|WP_000101096.1\|664654_665017_+\|response-regulator	gnl\|CDD\|381093	cd17538, REC_D1_PleD-like, first (D1) phosphoacceptor receiver (REC) domain of response regulator PleD and similar domains. PleD contains a REC domain (D1) with the phosphorylatable aspartate, a REC-like adaptor domain (D2), and the enzymatic diguanylate cyclase (DGC) domain, also called the GGDEF domain according to a conserved sequence motif, as its output domain. The GGDEF-containing PleD response regulators are global regulators of cell metabolism in some important human pathogens. This model describes D1 of PleD and similar domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.79368e-36
NZ_CP012006.1\|WP_001005337.1\|687195_688671_+\|alanine:cation-symporter-family-protein	gnl\|CDD\|376500	pfam01235, Na_Ala_symp, Sodium:alanine symporter family.	0
NZ_CP012006.1\|WP_034129408.1\|684112_685327_+\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.36746e-95
NZ_CP012006.1\|WP_001984830.1\|681810_683985_-\|TIGR01666-family-membrane-protein	gnl\|CDD\|130727	TIGR01666, Uncharacterized_protein_HI_1680, TIGR01666 family membrane protein. This model represents a clade of sequences from gamma and beta proteobacteria. These proteins are >700 amino acids long and many have been annotated as putative membrane proteins. The gene from Salmonella has been annotated as a putative efflux transporter. The gene from E. coli has the name yccS. [Cell envelope, Other].	0
NZ_CP012006.1\|WP_000077301.1\|675938_676442_+\|L,D-transpeptidase	gnl\|CDD\|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	8.56335e-26
NZ_CP012006.1\|WP_001016573.1\|672902_674039_-\|succinyl-diaminopimelate-desuccinylase	gnl\|CDD\|237265	PRK13009, PRK13009, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NZ_CP012006.1\|WP_000389061.1\|664247_664631_+\|response-regulator	gnl\|CDD\|381093	cd17538, REC_D1_PleD-like, first (D1) phosphoacceptor receiver (REC) domain of response regulator PleD and similar domains. PleD contains a REC domain (D1) with the phosphorylatable aspartate, a REC-like adaptor domain (D2), and the enzymatic diguanylate cyclase (DGC) domain, also called the GGDEF domain according to a conserved sequence motif, as its output domain. The GGDEF-containing PleD response regulators are global regulators of cell metabolism in some important human pathogens. This model describes D1 of PleD and similar domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.27194e-36
NZ_CP012006.1\|WP_001259501.1\|675419_675788_+\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	4.46882e-39
NZ_CP012006.1\|WP_001984826.1\|674164_674308_-\|entericidin-A/B-family-lipoprotein	gnl\|CDD\|227797	COG5510, COG5510, Predicted small secreted protein [Function unknown].	4.44613e-07
NZ_CP012006.1\|WP_000473032.1\|678430_680977_-\|PepSY-domain-containing-protein	gnl\|CDD\|99797	cd06200, SiR_like1, Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ gene) are of the cytochrome p450 (CyPor) family having FAD and FMN as prosthetic groups and utilizing NADPH. Cypor (including cyt -450 reductase, nitric oxide synthase, and methionine synthase reductase) are ferredoxin reductase (FNR)-like proteins with an additional N-terminal FMN domain and a connecting sub-domain inserted within the flavin binding portion of the FNR-like domain. The connecting domain orients the N-terminal FMN domain with the C-terminal FNR domain. NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via FAD and FMN. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria in which they participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues, and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule, which lies largely in a large gap betweed the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	4.52302e-132
NZ_CP012006.1\|WP_034129410.1\|665077_665614_+\|purine-binding-chemotaxis-protein-CheW	gnl\|CDD\|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	1.6552e-30
NZ_CP012006.1\|WP_034129409.1\|665660_667739_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	8.03475e-71
NZ_CP012006.1\|WP_005119701.1\|667885_672406_+\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	1.23501e-116
NZ_CP012006.1\|WP_001047593.1\|685354_686059_-\|nitroreductase	gnl\|CDD\|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	1.03168e-34
NZ_CP012006.1\|WP_000125649.1\|681134_681710_-\|SdpI-family-protein	gnl\|CDD\|379303	pfam13630, SdpI, SdpI/YfhL protein family. This family of proteins includes the SdpI and YfhL proteins from B. subtilis. The SdpI protein is a multipass integral membrane protein that protects toxin-producing cells from being killed. Killing is mediated by the exported toxic protein SdpC an extracellular protein that induces the synthesis of an immunity protein.	0.00838382

>NZ_CP012006.1|WP_001259501.1|675419_675788_+|YbaN-family-protein
MRTLFWRTLVVIFITLGIIGAILPGMPTTVFLILAAWAASKGWPQMDAWLLNHPKYGPTLRDWRANGTVPRKAKWIATIMMTASGILMLFTSAPFWVKVFTDTTMLVVAIWLWLRPEPKLKD
>NZ_CP012006.1|WP_001017534.1|674406_675315_-|DUF1853-family-protein
MNIASIKTSYFEPWLQFSHPMVRQLAFTIASPNLLSQLPCSLTIRHSFQLHTDKNWEQHFQNYLPRLKQLDEAPEPLLQFMSRLKSTRLGLRFENLLWFWLQEDQYHPYQLLGHSIQKIDGAKTLGELDFLVLNQNTQEIEHWEVALKYYLGEGQLNLEQWSGLNRQDTLSKKLYHFTDKQFQFSEALGFKVQQRFAVLKGQLYLPLNLPQEQPIPEWVNLKRRLGTWGTEIPKSDFYRLERHEWLCPHQKASSNTAYWWTDGLYCQNINETRFYMFRHPALLSLKPSLIKNNGVLQETTSL
>NZ_CP012006.1|WP_001984826.1|674164_674308_-|entericidin-A/B-family-lipoprotein
MMKKVLVASVMVAFVLTGCNTFKGFGQDVSKAGDAVTNTAQKTENKM
>NZ_CP012006.1|WP_001016573.1|672902_674039_-|succinyl-diaminopimelate-desuccinylase
MNHSDTLSLSLELLQQPSVTPIDHTCQTIMADRLAKVGFHIEPMRFGDVDNLWARRGTEGPVFCFAGHTDVVPTGRLDAWNSDPFAPEIRDGKLYGRGSADMKTALAAMVVASERFVAKHPNHKGSIAFLITSDEEGPAVNGTVKVIETLEKRNEKITWCLVGEPSSTHKLGDIVKNGRRGSLNAVLKVQGKQGHVAYPHLARNPIHEASPALAELCQTVWDNGNEYFPATSFQISNIHAGTGATNVIPGALEVTFNFRYSTEVTAEQLKQRVHEILDKHGLQYEIVWNLSGLPFLTPVGELVNAAQTAILNVTGTETELSTSGGTSDGRFIAPTGAQVLELGVLNATIHQINEHVDVHDLDPLTDIYEQILENLLAQ
>NZ_CP012006.1|WP_015451615.1|672438_672867_+|hypothetical-protein
MDQQELQHLITVSTGFIDAYIIECNDQVPMLLPQNIVLSAMDVKNGVKHIEWHDVKLPVYSVHNAIDQHAVALVIEGEDISQRFALICKTMPVSTRLRISEIVDEMDEHEAEQHPAVFKYVRMQHQRYYIPNLEYIEKTLGL
>NZ_CP012006.1|WP_005119701.1|667885_672406_+|hybrid-sensor-histidine-kinase/response-regulator
MKEILKTLTEAMTLPEDSYSEQDAEFLEIFIEEIEEIFVDLQPLINKWMQSENIATLTEIRRHFHTLKGSGRMIGAKSSAELAWAVEDTLNRVINQSLQLTPTIQSYVQLVFKFYFLKLVDNFKQKRAHTLDFRPLILLGQQLQQQQSLEPALEELLQLSNTLMAETVTGLELDYIEQDSLAEPIIQATHTEIEINLDETLTLFMEEAEEHLATIHQFLDQELHQYDSYNALIRALHTLRGSSAMAQVETIFEASTKVEHLFKILLQEELSSHSEEILLLQEYREFVRDSLELLSRYSSSEQLEARLQQFNQSWDAYVEQHGDRTDPLMPSHGLVSQLLQLDVSELLDAELDFEKGIRNEFPDYLERLSEQADLLLQHTHSQAMLGLHEYTSQLKESYEVLLDKPTLLQSDYIFEIYQKAHQQLIQLFDALAAGQRVGVVKQHQSILEELKLYTQYTPDLSNDLPQQDSTSFEPISNIEQEPEVVATVENFSDSVDWAVLGQSVQQDRQYISSTQVNRNFDADLLDIFLEEAEELLEGIDTDLNIWVGEQENFAALNNLMRYLHTLKGGANMVQATYLGLIAHELESIYERLIQKQLVATSDLIDFIRLVQDDLADRLQIMREQQLDYAAPYTINALKRAGQNSNFQPLPVVEAFDTESEIFSEQEVISEVIIDEIPVELEPALAELETHHDQVFDTAVTELATPVEMITTVTSQESEIAADEQDIEAVVEQTFLEEATELLEMAESLLKQWFEQRTNRSILLQLQRAVHSLKGGARMVGLEAVQAIAYQLENAFEQFALHHFNSNIYDHLLESAIAWLKDAIFNHNYQHFDGLQQSLENIQFFETTIQIPTKLTRADLFNSEPVMTFIQGDGTEPPPMMGAWEQTERLDQNNEMIRVSADLIEKMIDLSGENSINRSRIEMDLSQFSHTLVEMELAIQRLADQLRRMEGELETQIIAKHGIEHSRYTDFDPLEMDQYSSLNQLSKSLAESASDLVDFKNTLSDKIRDTESLLLQQSRIQAEIQEGLMRTRLVPFSRLLPRLQRIVRQTSTALNRPAELFVNNTEGELDRNILERLVTPLEHMLRNAIDHGLEDRMQRQQANKPETGRIELNIQRQGTDVVVVFSDDGQGIDVEKVRQKALLAGLIKPEQDLEQQDILQLIFHPGLSTAEQVTQISGRGVGLDVVQSDIKSLGGHVSVESIYGQGTTFTIRVPTTVAVSDALMVKVADQQFAIPLAQIDRIIRVSPASLEQYFESPQELFEYENKRYPLRYLSEFVGNQPIPRLNGVMYSLPVLMIKANNGQTVALLVDQLIGSRAQIVVKPIGQQFSSIGAIAGATILGDGQVCLILDGQNIARQIQSTQRHKQLSEAIYRQRESDERRLIMIVDDSVTVRKVTSRLLERQGYDVVTAKDGVDAIEQLENIKPDLMLLDIEMPRMDGFEVLNLVRHHDMHQYMPIIMITSRTGEKHRERAFSLGVSQYMGKPFQEEELLENIDALLVASDSEVKS
>NZ_CP012006.1|WP_034129409.1|665660_667739_+|methyl-accepting-chemotaxis-protein
MGFKLKKKSGNRGATGKSSVNFIAKIQSKIEQFASLFGESEKSKPILYAALLCLVCALISLAYLFYNVHRHNQLIRSLGELRLLSQTISKQATEATESGSQEAITKLQQSKKDFDENLLEIENIHGKSTDEYQKVEKIWGEVSKNIDLISSHQRVLNQLYDTNISISETVPEIQAEYNLMVDQMARQGLPSSQVIIAKNQVFIAERILRSINSVLSGTDGNVSTSDFSVDIETFGTYLNAELNGNAELGVDRIADPALRESLESIKSEYDKVLKSAAATVLKNGSQIVNVRQASSQIFSKSDVMLESLGHLSDVARKNWLTLFLGAVLILSLSGLIFSVFKLITLRSVMDKKRVARLQEEYDRNQNAILRLLDEIADLADGDLRSYATVSEDFTGAIADSINFAIDQLRDLVSRIHETSQEVARYTQDTQSITNQLAEASEHQAQEIAGASTAMNEMAQSIDQVSANASESAEVAQRSVQIASNGAQVVNRSIEGMDTIREQIQETSKRIKRLGESSQEIGNIVSLINDIADQTNILALNAAIQASMAGEAGRGFAVVADEVQRLAERSASATKQIETLVKTIQTDTNEAVISMEQTTTEVVRGANLAKDAGIALDEIQKVSGDLAKLIASISDAAKLQSASASHIATTMTVVQEITSQTTTATFDTARSVSELANMAESLRESVTDFKLPD
>NZ_CP012006.1|WP_034129410.1|665077_665614_+|purine-binding-chemotaxis-protein-CheW
MAANGFIELLRLSKRGNKNYASVQNEAQRWSGIAFEMRGQYFVAPLGEVSEVIYPPKYTPVPNTQSWVKGLANIRGRLLSVSDLAHFISGQWSSFSSTQKVLCISHHDQYVGLVVDQVLGIQHFNKKSFFSQSSDLEENLKEYCQGYFHQHNQHWHVFLFSRLLQNPHYMNASTKFIN
>NZ_CP012006.1|WP_000101096.1|664654_665017_+|response-regulator
MARILIVDDSPTETFRFKEILTKHGYDVLEASNGADGVTLAKAEQPDLVLMDVVMPGVNGFQATRQITRDEDTKHIPVVIVSTKDQATDRVWGKRQGAIDYLIKPIEEKQLIDVIKQFLN
>NZ_CP012006.1|WP_000389061.1|664247_664631_+|response-regulator
MEDAFQNLKVMVIDDSKTIRRTAETLLQREGCEVITAVDGFEALSKIAEANPDIVFVDIMMPRLDGYQTCALIKNSQNYQNIPVIMLSSKDGLFDQAKGRVVGSDEYLTKPFSKDELLNAIRNHVSS
>NZ_CP012006.1|WP_000077301.1|675938_676442_+|L,D-transpeptidase
MSQFKLEDADILIDLANQTLSLPKHNKFYVVSTGKNGIGEQENTGKTPRGWHRVAKKFGMQSPKNAVFIARQPTGEVYSSELAAQFPERDWILSRILWLDGLEEGFNKGEGHDTMQRYIYIHGTPDKEPMGVPMSHGCIRMRNEEIIELFDLVSEDALVYLSEQSLT
>NZ_CP012006.1|WP_001198164.1|677518_678304_-|YdcF-family-protein
MQVSKWIRIFLAVIGSILFLDGLFLAFLNKIHVGTLVPLVLGAFFCLYALFYYHLERFFFYHYRLHTLWRFGWLCFWIWLIGLGYFFNFIKENKDASQNLPAVKAIIVLGSGVENGQPSAILAKRLDTAAPVALSQPQAKVILTGGLDFSEKEPEALVMSRYLEQHFHIAKDRMILEDKSTSTELNLKNSKPLLEQAHISINQPIAIVTSDFHTPRAAAIAKKQGYTQVYMVAAETPLITRYNVWLREYFAYASGWLLNEY
>NZ_CP012006.1|WP_000473032.1|678430_680977_-|PepSY-domain-containing-protein
MFKKFLFQIHWFLGISAGLILSIMGVTGAIYSYDQQILKWVNTDSYVVQAQSSPKLTPAQLYQHFTTIQPEIKINSITIAKDPTASSVVNIEKEGERRGYNMMVNPYTAQVLPEVQGRKLLLLIQQIHRNLTAGEFGKQITGACALMLIYFVLSGLYLRWPKKHSARQWLALKPKLKGRNFIWDLHAVVGTWVIVFYLLFACTGLYWSYDWWRSGMFKVLGVEQPKMQGHSGSGRNKDQLPKIQLDNAQLITALNQTWSGFNNQIGRDYSTLTVNLPKKDDGKIELSFVDATPQHERARNQAVYNYKTANIEKMELYEDKKLNQKIMSSMLPVHRGSFFGPVYQFVAMLASLAMPLFFVTGWMLYLKRRKQKKLTQAARQSLAGHYIDQNAKPWLITYATQTGVAEQLAWSTATSLQEAHQPVQVKSVQQLTEADLQQHEQILFVISTYGTGEAPDLASNFAKKLLKTNLELQHVKYAVLALGSKEYPDTYCSFGYTVDEWLKNNGAKALFDIIEVDNANPADIQNWNQALVKATKLDLHAVNIEKVFDNWTLQQRDLLNPNSLGQPAYNIELTASHEAVWQAGDIAEIQPGNSPERINKFLQHHHILKNAVVDSLQVSIEKALWNKDLTGEIEPFANLDHLLEQLPTLPTREYSIASIPSQQVLRLVVRQQYDESGDLGLGSGWLTQHTEINQNVALRIRTNESFHLIDDNRPIICIGNGTGIAGLMSLLHTRTRHNYTENWLIFGERQRAHDFFYASTIEAWQTMGMLKRLDLAFSRDQEQRVYVQDIIRQNAAELVNWIERGAVLYVCGSIDGMASGVDQALIHILGEEQVDELRQQGRYRRDVY
>NZ_CP012006.1|WP_000125649.1|681134_681710_-|SdpI-family-protein
MTAKTLYAYTLQPVPYEVSEAEQRNAQLLIWRSTNKISTKIWAIMGVILALAILGLIFIKNYSTVICWVAIVCVVLYYLGRKYGLEWYVKRKMNEFPVQEIKGIRLGVQPHGIVMRQQMGLQEGVGTIGWKNIYEWYNTPDFILVNFKVKDPKGQEQQGAYILPKRMDSKNFSFNTIRKHLKESVGEPKTL
>NZ_CP012006.1|WP_001984830.1|681810_683985_-|TIGR01666-family-membrane-protein
MKSWFKRLKRATYNTSFMYNVRMLIAFSGTAFVPYFLGHQLATIPLTLGVVAAGLSDIDDRFSVRIMNLIYTYIGFFITAASVQLLFPYPMLFALGLIASCIGWILLGSLGRRYATISYGCLVVSVYTMLGVHLFDQWYIQPALLVAGAAWYGLIATISFLLFPVRQLQDKLAASYASLGDFLFAKSNLFDVDMTPASYQQSMIDLSLENGKLITIFNDLKTALLTRLKGDRGQKGTRRSLHYYFVAQDIHERADSAHIDYQKLAKIFQHSDILFRFQRILAIQGKACQELNECILQRKPYIHNKRFKQSFENLRLSLVKLRDDQQYDLLWVNALFALYRNLKSIDSQLLNLETEQHIQSDKVKQAENQLKDDDLKGWNDIVVRIKQNLTPESVLFRHAIRVSIVLFIGYVFIQMTHIEYGYWIMLTALFVSQPNFNATKRRLRLRIVGTLVGIIVGLSIVFLVPSVEGQLVMLILSGVLFFELRSKQYAQATAFITILALINFNLDGSAVAAAIPRFVDTLIGCALAWFGVTFIWPDWKFRRLPRSIRRSLQAQCNYLAEVVKQYHEGHNHALNYRIVRRAAHNTDAEVASLISTLATEPDFDPTRKSDIFEFLCLNHTFLSYIAALGAHREKIQDQAVLNVLDQALDDIQGALLRDEMPDLTAQNMLQTIRQRLSQNDEDDQKSLIILQQLSLMLSVLNRFSMLKQRLSHDLDNDASELASL
>NZ_CP012006.1|WP_034129408.1|684112_685327_+|multidrug-effflux-MFS-transporter
MSEQTAQRQYSIGWIMLLALLTALGPLSIDMYLPALPQMAHDFGVSTQMVANTLPAYFFGLAIGQLVYGPLSDRIGRKKPLYFGLALYAVASLFCVLATNEWSLIAARILQALGGCVGVVMARAAIRDRLDVQGSAQAFSSMMIVMGLAPILAPMIGAWILIWFPWQAIFIALSIVGAICWLCVHFFFKETLAVDKRLKLSLYQVATLYGAIFKDASFRLPMFAGCLTGAALFCYISSAPAVFMDQYGLNQQEFAYVFGLNAFGIMLMSSLNKHLTTRVEITKRLKAGSMVQVTGASIVLIAGLISAAPLWLVMLGLFLAISGIGLTGPNAMALAMSKQGARAGTASAIMGSMQFACGLLGGVLLNFLIWSASLNMGVMMVLFTLSGFIVVVKAIRQAKSQSLS
>NZ_CP012006.1|WP_001047593.1|685354_686059_-|nitroreductase
MNLEQVRLVDEAITSRHSVRAFLSTPIEPEVIKDILRVASRAPSGTNTQPWKVYVVTGHKRDEMVERVCAAQIEVSKNPELAEQYKETFAYYPEKWVSPFIDRRRENGWGLYGLLDIKKGEKEKMAAQQLRNFKLFDAPVGIFFTVNKAMGIGSKMDIAMMIQNVMVAAKARGLDTCPQAAWNHFHPLVLDILGAADDEELVCAIALGHADPEHIVNTFITPREPVENFAVFLD
>NZ_CP012006.1|WP_002010643.1|686569_686773_+|hypothetical-protein
MSLPLINKQFMKQGLAITIATMKMNVTHATTEPQEIQQLGTDLNALFFNEKEKGTDSRVMTMACYSL
>NZ_CP012006.1|WP_000490937.1|686955_687096_+|hypothetical-protein
MFSGAMNLFYLKGAFSHVTFKGLVLGMMLLKLVTVIAIQVTLKVFP
>NZ_CP012006.1|WP_001005337.1|687195_688671_+|alanine:cation-symporter-family-protein
MNEQLNATLMSWVQFFNEPLWDFLVIFLLAVGIFYTVLTGAVQIRMFLQSIRVMKSSRTEGEDEHGLTPFQAFVTGLASRVGVGNIAGVAIAIAIGGPGAVFWMWVTAVLGMSSAFIESTLAQLFKVRDSNSKQFRGGPAYYITQGLRSKTFGVIFALALIFTYGFVFNSVQINAIANASSHAWGWDKANLIAHLGGVDLEISWVGLALVVMVALAIFGGIKRIAKFAEMFVPLKAGLYLSVALYIALSNYAILPDVLKLIVTEAFHFNAAAGGFFGAAVSMAMMQGIKRGLFSNEAGMGSAPNAAAASDVKHPVNQGLVQMLGVFVDTFIVCTSTAIIILVSGVYQDAGFVGVELTQRALETQVGHWGADFLAVLLFLFCYSAVLGNYAYAESNVQFINNNPKVMFIFRIFVLVMVYFGAIGSVPLVWSMADLFMGIMATINLVAILLLTPMARTLLKDYRAQLKQGIKEPVFKINKYPELKKKVDSDIW

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Crispr_ID: NZ_CP012006_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012006_2

1731980-1732124

Orphan

Consensus_repeat	Method
CTAAAGCTTTGGCGAAGCGCAAGATGAACATAGTTATGGTTAATTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012006_2

>merge|NZ_CP012006|2|1731980-1732124|CRISPRCasFinder
CTAAAGCTTTGGCGAAGCGCAAGATGAACATAGTTATGGTTAATTTGTATTGAACTTTTTACAGGTATAAAAAAACGCCACCTGAGCAAGACAAAGCGGCTAAAGCTTTGGCGAAGCGCGAGATGAACATAGTTATGGTTAATTT

>NZ_CP012006|2|2|1731980-1732124|CRISPRCasFinder
CTAAAGCTTTGGCGAAGCGCAAGATGAACATAGTTATGGTTAATTT	GTATTGAACTTTTTACAGGTATAAAAAAACGCCACCTGAGCAAGACAAAGCGG
CTAAAGCTTTGGCGAAGCGCGAGATGAACATAGTTATGGTTAATTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012006.1\|WP_001202783.1\|1726602_1727397_+\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP012006.1\|WP_000121851.1\|1728594_1728918_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273177
NZ_CP012006.1\|WP_000955081.1\|1733083_1733410_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012006.1\|WP_000129939.1\|1729533_1730742_+\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|235056
NZ_CP012006.1\|WP_001187342.1\|1733517_1734624_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP012006.1\|WP_000838061.1\|1724337_1724757_-\|heme-binding-protein	unknown	unknown	gnl\|CDD\|225734
NZ_CP012006.1\|WP_077163451.1\|1731364_1731697_-\|DUF2750-domain-containing-protein	unknown	unknown	gnl\|CDD\|378546
NZ_CP012006.1\|WP_000593796.1\|1736378_1736903_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP012006.1\|WP_000616034.1\|1732174_1732408_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012006.1\|WP_000138830.1\|1728964_1729306_-\|Grx4-family-monothiol-glutaredoxin	unknown	unknown	gnl\|CDD\|188046
NZ_CP012006.1\|WP_000175351.1\|1735634_1736306_+\|DUF2057-domain-containing-protein	unknown	unknown	gnl\|CDD\|378258
NZ_CP012006.1\|WP_000954523.1\|1727448_1728351_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176162
NZ_CP012006.1\|WP_000185571.1\|1732623_1732983_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012006.1\|WP_000575163.1\|1737330_1738476_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|129307
NZ_CP012006.1\|WP_000156920.1\|1730792_1731224_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341391
NZ_CP012006.1\|WP_000102943.1\|1734812_1735409_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP012006.1\|WP_001186687.1\|1724948_1726250_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|185331
NZ_CP012006.1\|WP_085916945.1\|1736915_1737215_-\|cyd-operon-YbgE-family-protein	unknown	unknown	gnl\|CDD\|370577
NZ_CP012006.1\|WP_000949688.1\|1723832_1724078_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012006.1\|WP_000270276.1\|1737215_1737317_-\|cytochrome-bd-I-oxidase-subunit-CydX	unknown	unknown	gnl\|CDD\|369733

Protein	Function_ID	Function_description	E-value
NZ_CP012006.1\|WP_001202783.1\|1726602_1727397_+\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	4.40373e-150
NZ_CP012006.1\|WP_000121851.1\|1728594_1728918_+\|hypothetical-protein	gnl\|CDD\|273177	TIGR00617, Replication_protein_A_70_kDa_DNA-binding_subunit, replication factor-a protein 1 (rpa1). All proteins in this family for which functions are known are part of a multiprotein complex made up of homologs of RPA1, RPA2 and RPA3 that bind ssDNA and function in the recognition of DNA damage for nucleotide excision repairThis family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	0.00742828
NZ_CP012006.1\|WP_000270276.1\|1737215_1737317_-\|cytochrome-bd-I-oxidase-subunit-CydX	gnl\|CDD\|369733	pfam08173, YbgT_YccB, Membrane bound YbgT-like protein. This family contains a set of membrane proteins, typically 33 amino acids long. The family has no known function, but the protein is found in the operon CydAB in E. coli. Members have a consensus motif (MWYFXW) which is rich in aromatic residues. The protein forms a single membrane-spanning helix. This family seems to be restricted to Proteobacteria.	2.3152e-06
NZ_CP012006.1\|WP_000129939.1\|1729533_1730742_+\|aspartate-aminotransferase-family-protein	gnl\|CDD\|235056	PRK02627, PRK02627, acetylornithine aminotransferase; Provisional.	0
NZ_CP012006.1\|WP_001187342.1\|1733517_1734624_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	8.49853e-180
NZ_CP012006.1\|WP_000838061.1\|1724337_1724757_-\|heme-binding-protein	gnl\|CDD\|225734	COG3193, GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only].	2.71548e-31
NZ_CP012006.1\|WP_077163451.1\|1731364_1731697_-\|DUF2750-domain-containing-protein	gnl\|CDD\|378546	pfam11042, DUF2750, Protein of unknown function (DUF2750). This family is conserved in Proteobacteria. The function is not known.	1.42209e-20
NZ_CP012006.1\|WP_000593796.1\|1736378_1736903_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.08011e-05
NZ_CP012006.1\|WP_000138830.1\|1728964_1729306_-\|Grx4-family-monothiol-glutaredoxin	gnl\|CDD\|188046	TIGR00365, TIGR00365, monothiol glutaredoxin, Grx4 family. The gene for the member of this glutaredoxin family in E. coli, originally designated ydhD, is now designated grxD. Its protein, Grx4, is a monothiol glutaredoxin similar to Grx5 of yeast, which is involved in iron-sulfur cluster formation. [Energy metabolism, Electron transport].	2.75898e-66
NZ_CP012006.1\|WP_000175351.1\|1735634_1736306_+\|DUF2057-domain-containing-protein	gnl\|CDD\|378258	pfam09829, DUF2057, Uncharacterized protein conserved in bacteria (DUF2057). This domain, found in various prokaryotic proteins, has no known function.	4.46817e-29
NZ_CP012006.1\|WP_000954523.1\|1727448_1728351_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176162	cd08473, PBP2_CrgA_like_4, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 4. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.44498e-97
NZ_CP012006.1\|WP_000156920.1\|1730792_1731224_-\|CBS-domain-containing-protein	gnl\|CDD\|341391	cd04623, CBS_pair_bac_euk, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and eukaryotes. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.93176e-56
NZ_CP012006.1\|WP_000102943.1\|1734812_1735409_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	1.21707e-108
NZ_CP012006.1\|WP_001186687.1\|1724948_1726250_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|185331	PRK15433, PRK15433, branched-chain amino acid transporter carrier protein BrnQ.	2.27982e-171
NZ_CP012006.1\|WP_085916945.1\|1736915_1737215_-\|cyd-operon-YbgE-family-protein	gnl\|CDD\|370577	pfam09600, Cyd_oper_YbgE, Cyd operon protein YbgE (Cyd_oper_YbgE). This entry describes a small protein of unknown function, about 100 amino acids in length, essentially always found in an operon with CydAB, subunits of the cytochrome d terminal oxidase. It appears to be an integral membrane protein. It is found so far only in the Proteobacteria.	3.65946e-19
NZ_CP012006.1\|WP_000575163.1\|1737330_1738476_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|129307	TIGR00203, ubiquinol_oxidase_subunit_2, cytochrome d oxidase, subunit II (cydB). part of a two component cytochrome D terminal complex. Terminal reaction in the aerobic respiratory chain. [Energy metabolism, Electron transport].	3.94189e-149

>NZ_CP012006.1|WP_077163451.1|1731364_1731697_-|DUF2750-domain-containing-protein
MIKIYILRTMMYCGVLWGLFDEGWAIKSDQEDFIFPFWLNGVQAHRYAKTHWPNYKPRKITPKDFHESLLPTLTRLKVTPALFNSSHRKLKLSTQQMHHFFFNHPKWQVA
>NZ_CP012006.1|WP_000156920.1|1730792_1731224_-|CBS-domain-containing-protein
MTIVAQVIKNKSEQAIFTISPEATVLEAITIMAEKGIGALVVAEGEQVVGILSERDYTRKVTLMERSSYSTTVAEIMTAKVITVGLNNTVEECLQLMTDRHLRHLPVLDNGKLVGFISIGDLVKAAMEDQKVLIEQLKQYISG
>NZ_CP012006.1|WP_000129939.1|1729533_1730742_+|aspartate-aminotransferase-family-protein
MTDITLAPVQPDQPTHLMATYGRQAISFVRGRGAYLYAQDGTEYLDALTGIAVCGLGHAHPAIAEAIAEQAATLVHTSNLFEIPWQTAAAQKLAEVSGMEEIFFSNSGAESNEGAIKIARKFGTQQGISLPKIIVAEQSFHGRTLATLSATGNKKVQDGFAPLVEGFIRVPFGDIEAIQEAALQHPDIVAILIEPIQGEGGINTAPQGFSYLEEVRQNCNQHNWLMMLDEIQTGNGRTGKYFAYQHTNIIPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYTVIDTIQKENAVENAAVVGNYIVDQLRAQLSDKNVQVRGFGMMIGIQLPKDCAELVAIARDEYKLIINVTAGSVVRLLPPINMTQAQADILLERLVALITNYL
>NZ_CP012006.1|WP_000138830.1|1728964_1729306_-|Grx4-family-monothiol-glutaredoxin
MTEQARDTEALIRDQIAKHPVLLYMKGTPQFPQCGFSARAVEALSQIGRPFAYVNILENPDIRATLPKIANWPTFPQLWVNGELIGGSDIMLEMFQNGELKPLIEQYSAAPEA
>NZ_CP012006.1|WP_000121851.1|1728594_1728918_+|hypothetical-protein
MSYQLVELENATANIICPICKLAVIDWTQEQYVQPCEHTVFIAMDLGFEFVADRFEQVMNQNVDELHEDPNMNIFDAITTTPYKNLTILKADLGVDGLFRYVGISVC
>NZ_CP012006.1|WP_000954523.1|1727448_1728351_-|LysR-family-transcriptional-regulator
MLTDLDDFYCFALVVEHGGFSAAERVTDIPKSKLSRRVYNLEENLGVRLIQRSSRHFAVTDIGMDIYRHAQVMMNAAQAAHDLVDHLSIQPRGVVKVSVPVDIAQNQLPKILPAFLKKYPEIRLQLIVSNRRVDVINEGIDIALRVRSKLDDDPSLVLRQFALIEQSLFASQAYLNEFGNIKSPDELSDHRILSLSEEHLDQQFILHGPDNQLKKVKVSPTIMGTNIYMLAQLASQNCGIALLPDTAAEDFVKSGQLVQILPDWKAAHGIFHAVYPSRRGLLPAVRVFIDYLVEHLSEHP
>NZ_CP012006.1|WP_001202783.1|1726602_1727397_+|type-I-methionyl-aminopeptidase
MRASTVTIKTEQDLEKLRVSGRLAAQVLEMIGEYVKPGVTTEYLDNICNDYIVNTLKVIPANVGYHGFTKTICTSVNEVVCHGIPSQNKILKDGDIINIDVAIIKDGYFGDTSRMYYVGNVNPHAKKLVETTYEAMVAGIHVVKPGATLGDIGYAIQSVAHREGYSIVREYCGHGIGKVYHEQPNILHYGQRGQGLVLKKGMVFTIEPMVNAGKPQVKELNDGWTVITQDHSLSAQWEHMVAVTDTGFELLTPWPEGVGNYPEI
>NZ_CP012006.1|WP_001186687.1|1724948_1726250_-|branched-chain-amino-acid-transport-system-II-carrier-protein
MQQLRTGDIIALGFMTFALFIGAGNIIFPPIVAQQAGDHVWLAAIGFLITAVGLPVITIMALSRMQGSIEIISSPLGRIASLILTVVCYLSVGPLFATPRTATVSYEIGFSSYFGTSSSSLLIYSAIYFAFVTVVSLYPNKLLDTVGHVLAPLKIIALAILGIAAVMIPAGYVPTPINHYVNSPVSEGFVNGYLTMDTLGALVFGIVIIQAIYSRGVTDNKLVTKYAIIASLISGVGLTLVYLSLFKLGLGSHEVAPNAANGAVILHAYVQHAFGNMGSLFLTGLIFLACMVTAIGLTCACAEYFAQLTKLPYKLLVFILVGFSFIISNLGLTKLIAVSVPVLSAIYPPAIVVIMLSFFWKFWHKPSFIVGSVTSIALIFGIIDGLKVAGFGDYLPNFLQHLPLNEQNLAWLIPSLVVLVVTTLIDKVKHKSI
>NZ_CP012006.1|WP_000838061.1|1724337_1724757_-|heme-binding-protein
MKSKYYLTLADAEFLMEEAQKYAIEHNFKVSIAIVDETSSLLLMKRLDGASPLTTHLCLEKAKCSSMSGRPSKFYEELLQNGRLGFLSMPSAKGMLEGGKAIIYEGQILGAIGVSGVQSFEDAEIAQHAIDVFLKKQCS
>NZ_CP012006.1|WP_000949688.1|1723832_1724078_-|hypothetical-protein
MLSLHFNKQVFINTLNSKDSVVYGVTTLALMLTLLFQGMIKGNLKPEYFMYAMVVSFVFCVWAFVDHKMRKLAKRRLSQQK
>NZ_CP012006.1|WP_000616034.1|1732174_1732408_-|hypothetical-protein
MIQRISHHDLEHVYATAVNTIQSQMNFQDAVAQLEEVARAGHGKAALFLAELYYQGFRVERDSMKAQYWQKLATMQA
>NZ_CP012006.1|WP_000185571.1|1732623_1732983_+|hypothetical-protein
MTNTIDGFVFDNPPKEEQIIELAHYHRKLLDEAIFHQEIHLGDYCLAQRKRVFDYARQLDPNQKAWFYQVYDGELRKIADEDELHPADAEEGLSIFAMLLVLVIIAAILYFSVIRSLMG
>NZ_CP012006.1|WP_000955081.1|1733083_1733410_+|hypothetical-protein
MLTFKENFLKLKSELKADQCFNLVVIIIIGCIFMLSYLALLGPVNSEQYQRIVQLSRQATYPRTQDMAELIMAQSEIHRAEYLKLMHAYQFEHNHIKQYPALAQEDTQ
>NZ_CP012006.1|WP_001187342.1|1733517_1734624_+|signal-recognition-particle-docking-protein-FtsY
MQQQSNMQNKFLIDAEIGDDDVTLPNLPAIDVPIVESPVKQEVKAEEVVEAAPSTEPEQPKSGFFGRMKEGLSKTRRNFTDGMVNILIGGKEIDDELLEEVEEQLLVADIGVDATKTIITNLTERTARGDLIYSHSLYKALQEELVALLAPRVKPLHIDPNKSPYVILMVGVNGVGKTTTIGKLAKRLQGEGKKVMLAAGDTFRAAATEQLQIWGERNDIAVVAQGHGADSASVIFDAFESARAKGIDVLIADTAGRLHNKSNLMEELKKVKRVMQKIDATAPHEIMLVVDAGTGQNAINQVQEFDQAVGLTGITITKLDGTAKGGVLFNIASRTHVPIRFIGVGEKIDDLRPFSAKSFVAALFETEK
>NZ_CP012006.1|WP_000102943.1|1734812_1735409_+|nitroreductase-family-protein
MSTFLDKIKNRRTIYAIGKNVALDRTKIEETIREAVKHSPSAFNSQSSRVVTLYGESHAKFWNLVREALRKIVPADAFAGTNAKIDSFVAGVGTVLFYEDQAVVKSLQEQFELYADNFPVWSEHSSAIAQFATWTALSELGLGASLQHYNPIVDADAAEAFDVPATWKLRAQLVFGSVEAPAGEKAFISDEDRFKTFN
>NZ_CP012006.1|WP_000175351.1|1735634_1736306_+|DUF2057-domain-containing-protein
MTLRLSVAAMGLLLSGSVFSAVTITAPEEIVILAVNGQEVNSGLFRSSKNNYKVDAGETSLSVRYQEYFEHLSGEHDIVKSGVVTIQTPALKDGQTYKLAMVDAPKQFEQAKKYAEQPTVALYNSNNELIVQQTGANNEARPWFASGLLGKVTDFTTKSSKQQPDAVYAVAKPTTTQANAPVATTMPPTGVAQTNDQRLAEIWKKSSKAERQKFMAWLAEQSN
>NZ_CP012006.1|WP_000593796.1|1736378_1736903_+|GNAT-family-N-acetyltransferase
MIKLNFRLAEFSDIPTLVELINQSYREQQGRSWTTEVEYVKGQRINKEQLKHQLELPNSVLLIGEIDSSKVVTCIGLTFQSNTVEIGTFCTDPHVQNMKIGRCVLEYAEQFALHKVPELDSAIMYVLNVRSELIAYYERRGYIKTGNHEPYPLDANVGLPLIPIKLIEMKKDLK
>NZ_CP012006.1|WP_085916945.1|1736915_1737215_-|cyd-operon-YbgE-family-protein
MMATAMTASNQRKAQAFAMAISFLLALPLAVILLVHPSLMLDANGHYNHSQLMLVMVGISGGFIYGVGFVPHFWLWKWLFSPWIAWPLMLLGYYIWFLT
>NZ_CP012006.1|WP_000270276.1|1737215_1737317_-|cytochrome-bd-I-oxidase-subunit-CydX
MWYFAWILGILMACFAGVLSALYIEHHQNLDEE
>NZ_CP012006.1|WP_000575163.1|1737330_1738476_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MIEYELLKIIWWVLVGVLLIGFALTDGFDMGSMALMPFVGKTDNERRAAINTIAPHWDGNQVWFITAGGALFAAWPMVYSVAFSGMYWALLLVLFALFLRPVGFDYRSKLENTQWRNSWDWGLCIGGAVPALVFGVAFGNLFLGIPFSLDSTLRSEYSGSFFALLNPFALVCGIVSLSMLCAHGGAWLMLRTDGALKQRSAKATQIMAAIFLVCFLVIGAWLYFGQVPGYSYAAAVDPNAALNPLAKEVVTNNNPGWMNNYSSYPITKVAPVLAILGAIIAFFTASKAKAGLSFAGTSLMIVGAILTAGFALFPFLLPSSVNPNSSLTMWDAVSSHRTLGVMTVAACIFVPIILIYTSWSYYKMWGVITNKHIESNSHSLY

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Crispr_ID: NZ_CP012006_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012006_3

2008885-2008986

Orphan

Consensus_repeat	Method
CAAACCATTGCTTTGTTTATCCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012006_3

>merge|NZ_CP012006|3|2008885-2008986|CRISPRCasFinder
CAAACCATTGCTTTGTTTATCCTCTTCCACTCGAACATAGTTCTCGTCTTCTTGCGAAGCTTTAGTCGCTTCTCAGGACAAAGCATTGCTTTGTTTATCCTC

>NZ_CP012006|3|3|2008885-2008986|CRISPRCasFinder
CAAACCATTGCTTTGTTTATCCTC	TTCCACTCGAACATAGTTCTCGTCTTCTTGCGAAGCTTTAGTCGCTTCTCAGGA
CAAAGCATTGCTTTGTTTATCCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012006.1\|WP_001271394.1\|2015730_2017134_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|235798
NZ_CP012006.1\|WP_001289733.1\|2017144_2018680_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|273567
NZ_CP012006.1\|WP_000925651.1\|2007992_2008784_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP012006.1\|WP_001186401.1\|2002378_2003728_+\|chromate-efflux-transporter	unknown	unknown	gnl\|CDD\|273350
NZ_CP012006.1\|WP_004835232.1\|2004515_2004911_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP012006.1\|WP_000331400.1\|2004907_2005762_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227311
NZ_CP012006.1\|WP_000642319.1\|2013830_2014889_-\|2,3-butanediol-dehydrogenase	unknown	unknown	gnl\|CDD\|176195
NZ_CP012006.1\|WP_001133053.1\|2018681_2019701_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP012006.1\|WP_000238436.1\|2014918_2015704_-\|acetoin-reductase	unknown	unknown	gnl\|CDD\|187624
NZ_CP012006.1\|WP_000448778.1\|1999631_2001365_-\|fumarate-reductase/succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|181346
NZ_CP012006.1\|WP_000465452.1\|2010643_2011339_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293810
NZ_CP012006.1\|WP_000637000.1\|2012871_2013783_+\|bestrophin	unknown	unknown	gnl\|CDD\|376448
NZ_CP012006.1\|WP_000080821.1\|2001393_2002137_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP012006.1\|WP_001177517.1\|2019714_2020677_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|238958
NZ_CP012006.1\|WP_000822394.1\|2006878_2007883_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|168683
NZ_CP012006.1\|WP_000364551.1\|2021041_2022028_+\|lipoyl-synthase	unknown	unknown	gnl\|CDD\|237261
NZ_CP012006.1\|WP_031958193.1\|2011530_2012802_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP012006.1\|WP_000771644.1\|2003811_2004420_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|234675
NZ_CP012006.1\|WP_001023744.1\|2005928_2006846_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP012006.1\|WP_000864074.1\|1999365_1999611_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|224069

Protein	Function_ID	Function_description	E-value
NZ_CP012006.1\|WP_001271394.1\|2015730_2017134_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NZ_CP012006.1\|WP_001289733.1\|2017144_2018680_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|273567	TIGR01349, PDHac_trf_mito, pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form. This model represents one of several closely related clades of the dihydrolipoamide acetyltransferase subunit of the pyruvate dehydrogenase complex. It includes sequences from mitochondria and from alpha and beta branches of the proteobacteria, as well as from some other bacteria. Sequences from Gram-positive bacteria are not included. The non-enzymatic homolog protein X, which serves as an E3 component binding protein, falls within the clade phylogenetically but is rejected by its low score. [Energy metabolism, Pyruvate dehydrogenase].	3.67023e-121
NZ_CP012006.1\|WP_000925651.1\|2007992_2008784_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	9.27594e-23
NZ_CP012006.1\|WP_001186401.1\|2002378_2003728_+\|chromate-efflux-transporter	gnl\|CDD\|273350	TIGR00937, Chromate_transport_protein, chromate transporter, chromate ion transporter (CHR) family. Members of this family probably act as chromate transporters, and are found in Pseudomonas aeruginosa, Alcaligenes eutrophus, Vibrio cholerae, Bacillus subtilis, Ochrobactrum tritici, cyanobacteria and archaea. The protein reduces chromate accumulation and is essential for chromate resistance. [Transport and binding proteins, Anions].	2.57835e-60
NZ_CP012006.1\|WP_004835232.1\|2004515_2004911_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	9.44811e-39
NZ_CP012006.1\|WP_000331400.1\|2004907_2005762_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	4.38745e-34
NZ_CP012006.1\|WP_000642319.1\|2013830_2014889_-\|2,3-butanediol-dehydrogenase	gnl\|CDD\|176195	cd08233, butanediol_DH_like, (2R,3R)-2,3-butanediol dehydrogenase. (2R,3R)-2,3-butanediol dehydrogenase, a zinc-dependent medium chain alcohol dehydrogenase, catalyzes the NAD(+)-dependent oxidation of (2R,3R)-2,3-butanediol and meso-butanediol to acetoin. BDH functions as a homodimer. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit.	0
NZ_CP012006.1\|WP_001133053.1\|2018681_2019701_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	3.26675e-168
NZ_CP012006.1\|WP_000238436.1\|2014918_2015704_-\|acetoin-reductase	gnl\|CDD\|187624	cd05366, meso-BDH-like_SDR_c, meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs. 2,3-butanediol dehydrogenases (BDHs) catalyze the NAD+ dependent conversion of 2,3-butanediol to acetonin; BDHs are classified into types according to their stereospecificity as to substrates and products. Included in this subgroup are Klebsiella pneumonia meso-BDH which catalyzes meso-2,3-butanediol to D(-)-acetonin, and Corynebacterium glutamicum L-BDH which catalyzes lX+)-2,3-butanediol to L(+)-acetonin. This subgroup is comprised of classical SDRs with the characteristic catalytic triad and NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.14898e-114
NZ_CP012006.1\|WP_000448778.1\|1999631_2001365_-\|fumarate-reductase/succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|181346	PRK08275, PRK08275, putative oxidoreductase; Provisional.	0
NZ_CP012006.1\|WP_000465452.1\|2010643_2011339_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.07982e-87
NZ_CP012006.1\|WP_000637000.1\|2012871_2013783_+\|bestrophin	gnl\|CDD\|376448	pfam01062, Bestrophin, Bestrophin, RFP-TM, chloride channel. Bestrophin is a 68-kDa basolateral plasma membrane protein expressed in retinal pigment epithelial cells (RPE). It is encoded by the VMD2 gene, which is mutated in Best macular dystrophy, a disease characterized by a depressed light peak in the electrooculogram. VMD2 encodes a 585-amino acid protein with an approximate mass of 68 kDa which has been designated bestrophin. Bestrophin shares homology with the Caenorhabditis elegans RFP gene family, named for the presence of a conserved arginine (R), phenylalanine (F), proline (P), amino acid sequence motif. Bestrophin is a plasma membrane protein, localized to the basolateral surface of RPE cells consistent with a role for bestrophin in the generation or regulation of the EOG light peak. Bestrophin and other RFP family members represent a new class of chloride channels, indicating a direct role for bestrophin in generating the light peak. The VMD2 gene underlying Best disease was shown to represent the first human member of the RFP-TM protein family. More than 97% of the disease-causing mutations are located in the N-terminal RFP-TM domain implying important functional properties. The bestrophins are four-pass transmembrane chloride-channel proteins, and the RFP-TM or bestrophin domain extends from the N-terminus through approximately 350 amino acids and contains all of the TM domains as well as nearly all reported disease causing mutations. Interestingly, the RFP motif is not conserved evolutionarily back beyond Metazoa, neither is it in plant members.	4.15884e-82
NZ_CP012006.1\|WP_000080821.1\|2001393_2002137_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.17942e-74
NZ_CP012006.1\|WP_001177517.1\|2019714_2020677_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	gnl\|CDD\|238958	cd02000, TPP_E1_PDC_ADC_BCADC, Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain alpha-keto acid dehydrogenase/2-oxoisovalerate dehydrogenase complex (BCADC). PDC catalyzes the irreversible oxidative decarboxylation of pyruvate to produce acetyl-CoA in the bridging step between glycolysis and the citric acid cycle. ADC participates in the breakdown of acetoin while BCADC participates in the breakdown of branched chain amino acids. BCADC catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine).	1.46231e-132
NZ_CP012006.1\|WP_000822394.1\|2006878_2007883_-\|hypothetical-protein	gnl\|CDD\|168683	PRK06813, PRK06813, homoserine dehydrogenase; Validated.	7.04313e-77
NZ_CP012006.1\|WP_000364551.1\|2021041_2022028_+\|lipoyl-synthase	gnl\|CDD\|237261	PRK12928, PRK12928, lipoyl synthase; Provisional.	0
NZ_CP012006.1\|WP_031958193.1\|2011530_2012802_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.73922e-122
NZ_CP012006.1\|WP_000771644.1\|2003811_2004420_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|234675	PRK00170, PRK00170, azoreductase; Reviewed.	5.24919e-86
NZ_CP012006.1\|WP_001023744.1\|2005928_2006846_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	4.54094e-15
NZ_CP012006.1\|WP_000864074.1\|1999365_1999611_-\|ferredoxin-family-protein	gnl\|CDD\|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	8.24428e-10

>NZ_CP012006.1|WP_000925651.1|2007992_2008784_-|sulfite-exporter-TauE/SafE-family-protein
MLLLVVEGIVIGFLLGLTGAGGGILAVPALMTSQGWSVAQAAPIGLLAVALSTLIGTIEGLFKKIVRYRAAIWIALIGAPMAHIGILIANTISPIWLMLMFSLVMFTVGYRLINNRVSDFHNPPCQVNPSTGRFIWNFKTGGVLASIGIIAGLLTGMLGVGGGFVIVPALRKVTNLDMHSIVATSLMIIFLISGMSIVMHIAEGFQYPVAITSAFALACAFGMLLGRRAIRFIPSAIVQKVFALMVFAVAIYMVIKIVNLTNI
>NZ_CP012006.1|WP_000822394.1|2006878_2007883_-|hypothetical-protein
MKRINVAICGFGRIGQQIAELLLNRSTYYKQKYQIDARLVGVCNSSSGLIDQEGLQASKWLDKTQYQAGLTEQKFLKQVQADVIIETGPSDYVTGGKGLFYLNYALTHSMNAIAVSKGALVVEGKKLINLAHQHNKKLFFSGATAAALPTVDLFEYNLAGCQILEIESVFTGTTNFILNDMLQHECAFTESLEKAQARGIAEPNSSFDVDGWDTAAKITILANTVLGVDVKIQDIPRQGISHVTTEHIRDWKKENIIPRLVGFIHIKNQQIQTGVELRLVPANHPFAHLQGSNKCIRVLTQEMGEFVVSGGASAPLATAAAALKDFELMLKTGC
>NZ_CP012006.1|WP_001023744.1|2005928_2006846_+|EamA-family-transporter
MNILLYVAVVLIWGTTWIGIAVQSHYATPVVAILWRFAISALLLWVVLLFSGKLQRIALKDHLFCMLQGLCVFGLNFICFYTAVKYVNSGLESVIFSMAVFFNAINALIFFKQKPSPNFAPAALLGLSGIVLLFWHDLINSQFNAQLLMGIGLCAIGTYGFSLGNMISVRHQKRGLNIFSTNCYAMTYGALVMLILALFTGQDLMPPMNFPFLSSVLYLAVFGTVIGFSAYFSLVGRIGAAKAAYSTLLFPLVALTVSTFFEGYEWTLNAVFGILLILLGNYLMFSKFEIGKKLFSSQKNCEKQA
>NZ_CP012006.1|WP_000331400.1|2004907_2005762_-|AraC-family-transcriptional-regulator
MAYQTLEQLQQSKAKLHETVVLDENMQLAFWSNQQDRVSVCSDHHTLSLYIQDGYESYQKTPAGWKNGGGPGRFCLLPEHQESTWDIRGGLKFVHLYYTDQHLRDVAEKIWDKEPNQIELNEVVFNDDERIRALYQFFLLDCDWQDSSNHLQMSTTASLLLNHLIRKYSSVQWQQPTIKGGLAPHKLKYIQEWIEDHLDQALTLSDLANVVNLSEYHFAHMFKQSMNMAPHQYVMQRRLTKAKGLIQSSQLSLQDIALVCGFSSASHLSHRFKQFYGMSPSQLR
>NZ_CP012006.1|WP_004835232.1|2004515_2004911_+|helix-turn-helix-transcriptional-regulator
MTVTIPHDIQSSDCQRVSQVLARVGEKWSILIVMTLASHPHRFSEIKRRINGISQRMLTLCLRGLERDGLVKRTVYPVVPSHVEYELTPLGHSLTEPVIALGQWAQQHIADIDAARAAFDAAQEKPITLDT
>NZ_CP012006.1|WP_000771644.1|2003811_2004420_-|NAD(P)H-dependent-oxidoreductase
MKLLQIDTSILGEQSVSRQLTSSVIRQLSTAYPDAEIIHHDFALEPIPHLSDAEFLAWQGVEPNNEIAQQRVARNTQYLDEFLSSDIVVIGAPMYNFSFPSQLKAWLDRLSVAGKTFRYTENGPQGLVEGKRVIIASSRGGVYSEGSPAEALDYQETYIKAFFNFIGVTDITFVRAEGIAFGPEARQTALDNAAAQIAQLAG
>NZ_CP012006.1|WP_001186401.1|2002378_2003728_+|chromate-efflux-transporter
MQQKQLNTPDDSVEQVTFWQAILFWLKLGFISFGGPAGQIAVMHQELVEQKRWISEKRFLHALNYCMLLPGPEAQQLATYIGWLMHRTTGGLVAGILFVLPSLFILIGLSWVYIKFGDVPVISGIFYGIKPAVTAIVFHATYRIGSRSLKNKFLWFVAIAAFFAIFFLKLPFPLIVLSAGIAGYLASKKYPELFSSAAGHKASQKDYGPAIIDDDTPTPEHAKFHWLRLAKLIFVAIALWLLPILALGAYFGWHHSYTQMAWFFTKAALLTFGGAYAVLPYVYQGAVNHFGWLSPTQMIDGLALGETTPGPLIMVVAFVGFLGGVNHSLLGSEHLFFAGALGAVIVTWFTFLFSFVFIFAGAPIIESTHNEIKFTAPLTAITAAVVGVILNLALFFSYHVLWPQGFSGHFDIVAALITVAAFIALFRFNINVLYVIFASALVGLAVTFF
>NZ_CP012006.1|WP_000080821.1|2001393_2002137_-|GntR-family-transcriptional-regulator
MSQLPQDPKNHKPLYDQLRELILNKIVNGEYAVLSQIPSENEFAEQFGVSRITVRQALNQLQLEGYIFKVPGKGTFVSKPKTFQNISSLQGFAEAMSSAGHEILNRVISAELKQVPMHVVPKLKLPVKANVYEIQRVRLLNRQPVSYELTYLSEHIGLKLKEKAIDLRTTDIFKALEQECDIPLGHADLSIDATVADEELAALLQVEIGTPVLRVERLTHDANGQPIDYEYLYFSGDTFQYRLRIHR
>NZ_CP012006.1|WP_000448778.1|1999631_2001365_-|fumarate-reductase/succinate-dehydrogenase-flavoprotein-subunit
METKYFEFDIVVIGGGTAGPMAAIKAKQENPNLKVLLIEKANVKRSGAISMGMDGLNNAVIPGYATPEQYTKEITIANDGVVNQTTVYAYAKHSFTTIQQLDQWGIKFEKDETGEFAVKKVHHMGAYVLPMPEGHDVKKVLYRQLKRAQVKINNRIVTTKLLKNEQGAINGVLGFDCRSGDFYVIKTKAAILCCGAAGRLGLPASGYLMGTYENPTNAGDGYAMAYHAGAELANLECFQINPLIKDYNGPACAYVTGPLGGYTANSKGERFIECDYWSGQMMWEFYQELESGNGPVYLKVDHLAEETIQTIEEILHTNERPSRGRFHEGRGINYRQDMVEMHISEIGFCSGHSASGVWVNEKAETSVKGLYSAGDMAAVPHNYMLGAFTYGWFAGVNAAQYVNAVEDSELNQSEIEAEKARIFAPLDCSEGLPPEQVEYKLRRFVNDYLQPPKTRQKMEIGLKRFEEIKQDIKRISARNPHELMRAAEVSFIRDCAEMAARASLFREESRWGLYHYRADFPQKNNSDWFCHAHLKKDEHGNMVSFKKPIEPYVVPINQDEAVSYDRLRIQKDVALAD
>NZ_CP012006.1|WP_000864074.1|1999365_1999611_-|ferredoxin-family-protein
MAFIFKEVQHRTVAPVIIDEDKCIADKGCTVCVDVCPMDLLAIDPTTQKAYMQFDECWYCMPCEKDCPTDAVKVNIPYLLK
>NZ_CP012006.1|WP_000465452.1|2010643_2011339_-|MBL-fold-metallo-hydrolase
MFFKQFFEKESSTYTYMLGCEETRVAVLIDPVASDIEIYAKELEQHQFTLIYTLDTHVHADHITAADLLRERFHCKSVLHRNSDVSCGDILITDGCMLKVGNLSIEARYTPGHTNACTSYLVGNMIFTGDALLIDGCGRTDFQQGSAGTLYDSIHKQLFSLPDETIVYPGHDYKGRLSSTIGYERLNNSRLGQNRSREDFIELMNNLNLPYPKQIDKALPANQACGSISQL
>NZ_CP012006.1|WP_031958193.1|2011530_2012802_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MAKLNFELEQDFYILFEQLKALFPNAILFLVDTSTQAIHYKFNTDDISVESMAALTQDHHNQYLEINTPKMRRRFIYQEHDIYIAEHRIIGKLHILQPVSIENDIVDGVELTEQLQDLAKVFNSCSPEMTRMFSIIQRVAITEFPVLVRGESGSGKELVAKAIHDYSQRKNKIFVAINCAALNSNILESELFGHVKGAFTGAIRDHKGVFERAAGGTLFLDEIAEIPLELQAKLLRVLETGEFTPVGGEKPIQANVRIITATHKALREEAKAGRFRHDLLYRLRVIPIFIPPLRERKVDIPIIVDQILKESSTQLDTMPRHVNQKAMQVLLNYDWPGNVRELKNTLLYALTMANGKDEIEVEDLPNELLNADDYVKLPETNAELSPENVQAALEKYNHNLNMVANIFGISRTTLWRYRQKHKL
>NZ_CP012006.1|WP_000637000.1|2012871_2013783_+|bestrophin
MIVRDKSNVFKLLFAWKGTILPKVLPALSFVVLISACVVWLSYYHWIQIPTVPAIGFTIFGVILSICTGFRNNACYDRWWEGRKLWGALIANARHIVRDSHVLSNEQREHLIHQVLIFCNLLRDRLRQQTVEPTKFLEHAYLNNSSLNYLNEHINAPQFVLENIQKDLVKALKDGEISDIIYGTLTRHIVELGNIQAGCDRIAGTPLPYSYSVLLHRAVYCFCFILPFSLEAALGIWTPLIVGLIAYMFLGLDALSAQIEEPFGLQENDLPLDSIVRLIERESLSSLGQPLPPIIEAQNNNLL
>NZ_CP012006.1|WP_000642319.1|2013830_2014889_-|2,3-butanediol-dehydrogenase
MKAARFYDRGDIRIEDIPEPEVTPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGESAPITMGHEFSGVVYAVGEGVDDIEIGQHVVVEPYIVADDVPTGPGDNYHLSKNMNFIGLGGRGGGLSEKIAVKRRWVHPISNKIPLDQAALIEPLSVGHHAYVRSGAKAGDIALVGGAGPIGLLLSAILKAKGLKVIITELSAKRKEKAKESGVADYILDPSEVDVVSEVMKITNGDGVDVAFECSSVNKVLDTLVAAVKPTGVIVIVSIWSHPASINVHSVVMKELDVRGTIAYVNDHQETIKLVEEGKINLEPFITQRIQLDDLISQGFETLIHNNESAVKIIVHP
>NZ_CP012006.1|WP_000238436.1|2014918_2015704_-|acetoin-reductase
MVKGLKNKVALVTGAAQGIGRGIALRLAQEGAHIALVDMKQDRLNDVQQEIQALGVNASTFIADVSDREQVYAAINHAEQTLGGFDVMINNAGIAQVQAIADITPDEFQKIVDINIGGVLWGIQAAAAKFKQREHKGKIINACSIAGHDGFALLGIYSATKFAVRALTQAAAKEYASHGITVNGYCPGIVGTDMWVEIDKRFAEITGAAIGETYKKYVEGIALGRAQTPDDVAALVAFLASEDSDYITGQSILTDGGIVYR
>NZ_CP012006.1|WP_001271394.1|2015730_2017134_-|dihydrolipoyl-dehydrogenase
MSAAQFDLIVIGAGPGGYVAAIRAAQLGLKTAIVEEQHLGGICLNWGCIPTKALLAGAELATQFKHAGQFGFQVSQLDFDVQKLVQHSRQVSAQLVQGIDYLLKKNQVTVFNGRAQLTAKEKIEVTDAQGNSQVLSAPHIILATGAKARHVPQLPVDGTYVWSYKEALVPEQLPKSLLVVGSGAIGSEFASLYQDLGCQVTLIDLAKQILPTEDAEVAQFVRKQFEQKGMKVITDAVVQSIQIENEQVHCVVETANDVQTLVFDRVLSAIGVQPNTTGLGLERLGVELNPQGFVAIDDYCKTNVAGLYAIGDVAGAPCLAHKASHEAMICIEKIAGVANVHSLDRSQIPGCIFTHPQVASIGLTENAAKAKNLPIRIGKFSLTANGKALAIGDASGFVKTVVHAETGELLGAHMVGHEVTEHIQGFAIAKYLEATDESLAQVIFPHPTLSEAMHESILASMQRAIHM
>NZ_CP012006.1|WP_001289733.1|2017144_2018680_-|2-oxo-acid-dehydrogenase-subunit-E2
MSEIKTLEIPKWGLSMEEGTIAQWLIKEGDSFNKGDEICEIETTKIVNVLEAPFAGTLRKILAKDGDTLPVGGLIAVCADSEVSDAEIEKFIASLGGSAAQAPEAPSEQSKAETSAPVAEKTAQPQTAAASASAPAKVAKDDYAVPESLQGYQTSNELFATPHALKLAEKHNVNLAKVTGSGREGRISVQDIQKAVQASGGQWPDVRQQTQAKVVKSTADDSQVLATPVARRLAKQWGINLNDCRVSGTRGRVCKEDVEAVYYRNNPVSVSEQPVQCAAQPQSTVTTVAMNGMRKAIASRLQAAKRNAPHFRLVVDLNVEALQKLRKQINETVPQVKLSINDMLIKAAAAALIKVPEVNVQFDEATQSILQFSQADISVAVAIPNGLITPIVKAANQKSLAQISDDMRDLATRAKTGKLQPDEFQGGSFSISNLGMLGIKQFDAIINPPQGAIMALGASESRAVVENGNVVVREIVTATLSCDHRVIDGAVGAKFLASFKQFVENPALILV
>NZ_CP012006.1|WP_001133053.1|2018681_2019701_-|alpha-ketoacid-dehydrogenase-subunit-beta
MPNKSFRNAIKEAIESEMRRDPTVFVVGEDVRGGHGGKNTEENQLEGFGGVLGVTKGLWTEFGSERVIDTPITESAIIGMAAGAAATGLRPVADLMFMDFYGVCHDMLYNQAAKFRYMFGGKAKAPMVVRGMIGAGFSAAAQHSQSPYNVFAAVPGLKVVVPSSPYDVKGLLIQAIRDDDPVVFCEHKMLYDIKGEVPDDAYTIPFGVANYTREGTDVTIIALGLMVHRANEVADKLAKDGISVEVVDPRTISPLDEEGILESVASTGRVVIVDESAARCGFGHDVAALIAQKGFHYLKAPVELVTPPHTPVPFSPVLEKEWIPSVERIEQAVRKTLEA
>NZ_CP012006.1|WP_001177517.1|2019714_2020677_-|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha
MQLTEEQLLAAYKRMRDIREFEDRLHEENTNGDIPGFIHLYSGEEAVAVGICENLTDKDYITSTHRGHGHCIAKGCDIHAMMLEIFGKDDGLCRGKGGSMHIADLDKGMLGANGIVGGGPPLAIGAALTAKTLKTGGVGLSFTGDGGSNQGLTFEAMNMAVVLKLPVIFVFENNGFGEGTGHDYAVGSKDIAGRAAGFGLPAVKVDGTDFFAVYEAAQTAIERARRGEGPSVIETITNRFYGHFEGDPGLIRSKEEVEFIKENKDPLKIFREKVKGKIDEAKLDEIDAASKANVDDAVAKARAAAYPKPEQLLTDVYVSY
>NZ_CP012006.1|WP_000364551.1|2021041_2022028_+|lipoyl-synthase
MDLKRQIETGIKLRGIDKVSRIPIKILPTEELPKKPEWIRAKITDFEEIQRIKNLLRQQKLHSVCEEAACPNLPECFAGGTATFMIMGDICTRRCPFCDVAHGRPMPLDENEPKHLAETVANLNLKYVVITSVDRDDLHDGGAAHFVKCIEEIRNRCPDTLIEILVPDFRGRLETALSTLSLSPPDVFNHNIETVPRLYKAMRPGSDYQHSLNLLKRFKKYCPDIKTKCGLMVGLGEIEAEVIALLNDLKDHDVDLVTIGQYLQPSKSHAPIHRFVNLQEFERYTQHGQRLGFKNIWSAPMVRSSYFADRQYFGESAPKPFSREDVLS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1142330 : 1157127

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001187844.1\|1142330_1142879_-	GTP cyclohydrolase I FolE	A0A0P0HSD2	Acinetobacter_phage	1.7e-97	100.0
WP_000893694.1\|1143141_1144641_+	xanthine dehydrogenase small subunit	A0A0P0IVM8	Acinetobacter_phage	2.1e-278	97.0
WP_001076827.1\|1144642_1147018_+	xanthine dehydrogenase molybdopterin binding subunit	A0A0P0I429	Acinetobacter_phage	0.0e+00	97.9
WP_001164242.1\|1147024_1148008_+	xanthine dehydrogenase accessory protein XdhC	A0A0P0IKN7	Acinetobacter_phage	2.9e-183	96.3
WP_000066126.1\|1148018_1148714_-	Smr/MutS family protein	A0A0P0IDT4	Acinetobacter_phage	5.8e-122	100.0
WP_000608310.1\|1148723_1149530_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	3.9e-146	99.3
WP_001982145.1\|1149539_1150589_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	9.8e-190	100.0
WP_000281148.1\|1150944_1153677_+	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	0.0e+00	98.2
WP_074163530.1\|1153690_1156456_+	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	0.0e+00	98.7
WP_000566785.1\|1156551_1157127_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	A0A0P0IKJ1	Acinetobacter_phage	1.2e-109	99.5

DBSCAN-SWA_2

1201885 : 1257423

Acinetobacter_phage(87.3%)

integrase,terminase,capsid

attL 1200363:1200380|attR 1243862:1243879

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1200363:1200380	attL	NA	NA	NA	NA
WP_000110166.1\|1201885_1202698_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	A0A126HHM5	Vibrio_phage	5.0e-40	37.2
WP_001010537.1\|1202694_1203468_-	ABC transporter permease	NA	NA	NA	NA
WP_000128669.1\|1203464_1204400_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	8.3e-23	30.0
WP_000135934.1\|1204697_1205684_+\|integrase	site-specific integrase	A0A1B1P9F9	Acinetobacter_phage	6.4e-183	97.9
WP_049592411.1\|1205680_1205950_-	hypothetical protein	A0A1B1P9G0	Acinetobacter_phage	1.4e-47	98.9
WP_000927772.1\|1205951_1206221_-	hypothetical protein	A0A172Q0P4	Acinetobacter_phage	9.6e-17	56.1
WP_049580145.1\|1206232_1206448_-	hypothetical protein	NA	NA	NA	NA
WP_049592412.1\|1206444_1206882_-	hypothetical protein	A0A1B1P9F6	Acinetobacter_phage	1.0e-36	90.5
WP_049592413.1\|1206881_1207166_-	hypothetical protein	A0A0P0J0F2	Acinetobacter_phage	1.2e-36	86.7
WP_049592414.1\|1207171_1207540_-	hypothetical protein	A0A1B1P9I4	Acinetobacter_phage	6.5e-64	95.1
WP_001000839.1\|1207536_1207794_-	hypothetical protein	K4HYN5	Acinetobacter_phage	3.6e-29	77.5
WP_049592415.1\|1207790_1208399_-	YqaJ viral recombinase family protein	A0A2H4J882	uncultured_Caudovirales_phage	3.5e-83	75.3
WP_049592416.1\|1208379_1209237_-	phage recombination protein Bet	A0A088CBI3	Shigella_phage	1.9e-58	56.7
WP_001195991.1\|1209253_1209436_-	hypothetical protein	NA	NA	NA	NA
WP_049592417.1\|1209435_1209816_-	hypothetical protein	NA	NA	NA	NA
WP_049592418.1\|1209812_1210571_-	hypothetical protein	A0A068CDC2	Acinetobacter_phage	3.6e-32	43.5
WP_049592419.1\|1210563_1210794_-	hypothetical protein	A0A068CDE4	Acinetobacter_phage	9.8e-10	47.2
WP_049592420.1\|1210793_1210985_-	hypothetical protein	A0A1B1P9G9	Acinetobacter_phage	5.8e-16	70.6
WP_000065151.1\|1211184_1213452_-	N-6 DNA methylase	J7I0U9	Acinetobacter_phage	0.0e+00	100.0
WP_002042732.1\|1213584_1213800_-	hypothetical protein	A0A0P0I8I5	Acinetobacter_phage	5.5e-31	98.6
WP_000370562.1\|1213815_1214562_-	helix-turn-helix domain-containing protein	A0A1B1P9J5	Acinetobacter_phage	3.3e-107	79.7
WP_001100148.1\|1214667_1214856_+	hypothetical protein	NA	NA	NA	NA
WP_000166816.1\|1214864_1215140_+	hypothetical protein	NA	NA	NA	NA
WP_001109646.1\|1215180_1215339_+	hypothetical protein	A0A1B1P9H5	Acinetobacter_phage	7.9e-19	98.1
WP_049582456.1\|1216156_1217518_+	replicative DNA helicase	A0A1B1P9I0	Acinetobacter_phage	1.1e-225	86.8
WP_000644295.1\|1217514_1217766_+	hypothetical protein	A0A0P0IE39	Acinetobacter_phage	5.8e-40	98.8
WP_165959353.1\|1217762_1217939_+	hypothetical protein	A0A1B1P9H7	Acinetobacter_phage	1.8e-19	84.5
WP_049582453.1\|1217935_1218253_+	hypothetical protein	A0A0P0I8J0	Acinetobacter_phage	3.0e-25	59.6
WP_171249897.1\|1218245_1218422_+	hypothetical protein	NA	NA	NA	NA
WP_049582452.1\|1218414_1218696_+	hypothetical protein	NA	NA	NA	NA
WP_000356509.1\|1218697_1219075_+	hypothetical protein	A0A0D4DCN2	Acinetobacter_phage	4.0e-08	35.0
WP_049582449.1\|1219071_1219326_+	hypothetical protein	NA	NA	NA	NA
WP_049582446.1\|1219322_1219778_+	hypothetical protein	A0A0P0HSP6	Acinetobacter_phage	8.3e-77	97.3
WP_049582445.1\|1219774_1220044_+	hypothetical protein	A0A0D4DC03	Acinetobacter_phage	4.6e-43	97.8
WP_000990564.1\|1220054_1220534_+	hypothetical protein	A0A0P0I4C3	Acinetobacter_phage	8.2e-27	42.3
WP_025465323.1\|1221013_1221259_+	hypothetical protein	NA	NA	NA	NA
WP_000587871.1\|1221261_1221570_+	hypothetical protein	NA	NA	NA	NA
WP_079454608.1\|1221572_1221776_+	hypothetical protein	A0A1B1P9J1	Acinetobacter_phage	3.1e-28	97.0
WP_049582441.1\|1221726_1222002_+	hypothetical protein	A0A1B1P9J2	Acinetobacter_phage	5.6e-28	67.0
WP_043053751.1\|1222001_1222187_+	hypothetical protein	NA	NA	NA	NA
WP_000020582.1\|1222283_1223354_+	RelA/SpoT domain-containing protein	A0A1B0VBT5	Salmonella_phage	7.7e-33	32.6
WP_049582437.1\|1223411_1223903_+	hypothetical protein	A0A0D4DC11	Acinetobacter_phage	7.3e-63	72.6
WP_049582435.1\|1223924_1224581_+	hypothetical protein	NA	NA	NA	NA
WP_049582429.1\|1224622_1225057_+	hypothetical protein	J7HXN1	Acinetobacter_phage	8.1e-74	93.1
WP_049592421.1\|1225025_1225667_+	hypothetical protein	J7I4N9	Acinetobacter_phage	1.4e-125	99.1
WP_002067420.1\|1225725_1226196_+	DUF2280 domain-containing protein	A0A0D4DC15	Acinetobacter_phage	1.7e-72	87.8
WP_049592422.1\|1226185_1227613_+\|terminase	phage terminase large subunit	A0A0D4DCE6	Acinetobacter_phage	1.6e-259	94.3
WP_049592423.1\|1227609_1229061_+	DUF4055 domain-containing protein	A0A0D4DCP1	Acinetobacter_phage	2.1e-267	92.8
WP_000179751.1\|1229062_1230166_+\|capsid	minor capsid protein	A0A0D4DBL9	Acinetobacter_phage	7.8e-206	99.7
WP_000965231.1\|1230174_1230603_+	hypothetical protein	J7I4P3	Acinetobacter_phage	5.2e-73	100.0
WP_000004361.1\|1230701_1230944_+	hypothetical protein	A0A0P0IY55	Acinetobacter_phage	2.1e-39	100.0
WP_162986048.1\|1230959_1231112_+	hypothetical protein	NA	NA	NA	NA
WP_001139861.1\|1231163_1231355_+	hypothetical protein	A0A0P0IKM2	Acinetobacter_phage	1.7e-28	100.0
WP_000770049.1\|1231468_1232236_+	hypothetical protein	J7I0W4	Acinetobacter_phage	4.6e-120	100.0
WP_000214194.1\|1232263_1233217_+	Ig domain-containing protein	A0A0D4DBM4	Acinetobacter_phage	1.2e-167	94.0
WP_049592424.1\|1233281_1233947_+	stress-responsive nuclear envelope protein	J7I4P7	Acinetobacter_phage	1.1e-72	67.4
WP_000008494.1\|1233951_1234341_+	hypothetical protein	A0A0D4DC24	Acinetobacter_phage	6.6e-67	100.0
WP_049592425.1\|1234342_1234711_+	hypothetical protein	J7I467	Acinetobacter_phage	5.0e-64	98.4
WP_049592426.1\|1235536_1235944_+	hypothetical protein	A0A0P0IKR8	Acinetobacter_phage	1.6e-63	89.6
WP_049592427.1\|1235915_1236284_+	hypothetical protein	A0A0D4DBN1	Acinetobacter_phage	6.1e-54	82.0
WP_000178914.1\|1236285_1236684_+	hypothetical protein	A0A0P0IRA6	Acinetobacter_phage	4.2e-69	95.5
WP_015451444.1\|1236752_1237106_+	hypothetical protein	A0A0D4DCF7	Acinetobacter_phage	9.3e-60	100.0
WP_049592428.1\|1237105_1238254_+	fibronectin type III domain-containing protein	J7I0X3	Acinetobacter_phage	1.0e-152	86.3
WP_049592429.1\|1238306_1239224_+	hypothetical protein	A0A0P0IL42	Acinetobacter_phage	5.8e-162	94.1
WP_049592430.1\|1239293_1239809_+	hypothetical protein	A0A0N7IRG3	Acinetobacter_phage	1.9e-77	97.3
WP_001011615.1\|1240260_1240458_+	hypothetical protein	NA	NA	NA	NA
WP_032018977.1\|1240420_1241275_+	hypothetical protein	A0A0R6PIN1	Moraxella_phage	6.5e-59	43.9
WP_000734557.1\|1241374_1241899_+	DUF4468 domain-containing protein	A0A0P0I8L3	Acinetobacter_phage	2.1e-92	95.4
WP_148562194.1\|1241961_1246581_+	tape measure protein	A0A220VZA0	Acinetobacter_phage	0.0e+00	84.4
1243862:1243879	attR	NA	NA	NA	NA
WP_049592431.1\|1246631_1247030_+	hypothetical protein	J7I0X8	Acinetobacter_phage	1.8e-72	97.7
WP_049592432.1\|1247029_1247536_+	hypothetical protein	A0A0D4DCA4	Acinetobacter_phage	4.4e-87	92.3
WP_049592433.1\|1247532_1247895_+	hypothetical protein	A0A0P0J0A2	Acinetobacter_phage	1.2e-49	76.7
WP_049592434.1\|1247887_1251313_+	bacteriophage protein	A0A0D4DBG7	Acinetobacter_phage	0.0e+00	93.3
WP_000433907.1\|1251425_1251815_+	hypothetical protein	A0A0P0I8L9	Acinetobacter_phage	3.3e-66	99.2
WP_049582477.1\|1251856_1252402_+	N-acetylmuramidase	A0A0P0IW03	Acinetobacter_phage	9.5e-96	95.5
WP_041172232.1\|1252529_1252721_+	hypothetical protein	A0A1B1P9F8	Acinetobacter_phage	1.3e-28	96.8
WP_160948541.1\|1252978_1253614_-	hypothetical protein	NA	NA	NA	NA
WP_001147935.1\|1253758_1254445_-	DUF3820 family protein	A0A059VJT9	Pseudomonas_phage	1.1e-35	41.6
WP_020753345.1\|1254694_1255924_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_002036954.1\|1255947_1256109_-	hypothetical protein	NA	NA	NA	NA
WP_000457893.1\|1256169_1257423_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	2.3e-97	52.3

DBSCAN-SWA_3

1470448 : 1478680

Acinetobacter_phage(100.0%)

integrase,capsid

attL 1470282:1470297|attR 1483303:1483318

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1470282:1470297	attL	NA	NA	NA	NA
WP_020753295.1\|1470448_1471657_+\|integrase	integrase family protein	A0A0P0IKP2	Acinetobacter_phage	4.8e-108	48.0
WP_000039877.1\|1471653_1471923_-	helix-turn-helix domain-containing protein	A0A0N7IRE8	Acinetobacter_phage	1.8e-15	53.5
WP_049592458.1\|1472693_1473779_+\|capsid	minor capsid protein	A0A1B1P9B7	Acinetobacter_phage	2.9e-197	98.1
WP_004888437.1\|1473775_1473988_+	hypothetical protein	NA	NA	NA	NA
WP_049592459.1\|1474073_1474799_+	hypothetical protein	A0A1B1P9C7	Acinetobacter_phage	4.7e-74	90.9
WP_001139644.1\|1474816_1475833_+	hypothetical protein	A0A1B1P9D0	Acinetobacter_phage	1.1e-166	87.6
WP_000818586.1\|1475844_1476030_+	hypothetical protein	A0A1B1P9F4	Acinetobacter_phage	4.3e-24	86.7
WP_016653817.1\|1476086_1476473_+	hypothetical protein	A0A1B1P9F2	Acinetobacter_phage	1.6e-65	97.7
WP_049592460.1\|1476476_1476869_+	hypothetical protein	A0A1B1P9E3	Acinetobacter_phage	2.2e-62	90.0
WP_049592461.1\|1476873_1477329_+	hypothetical protein	A0A1B1P9D5	Acinetobacter_phage	5.8e-54	73.5
WP_049592462.1\|1477330_1477726_+	prophage PSSB64-02	A0A1B1P9D6	Acinetobacter_phage	2.0e-66	92.4
WP_049592463.1\|1477886_1478414_+	Rha family transcriptional regulator	A0A1B1P9D9	Acinetobacter_phage	3.9e-54	63.7
WP_009499909.1\|1478413_1478680_+	hypothetical protein	A0A1B1P9E1	Acinetobacter_phage	3.3e-41	90.9
1483303:1483318	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1524195 : 1642053

124

Acinetobacter_phage(72.88%)

capsid,holin,terminase,protease,coat,integrase,transposase

attL 1546364:1546380|attR 1632519:1632535

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000750672.1\|1524195_1524726_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_000739317.1\|1524798_1525503_+	molecular chaperone	NA	NA	NA	NA
WP_000873967.1\|1525512_1527972_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_000055764.1\|1527962_1528982_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_001279982.1\|1529208_1529895_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_000920706.1\|1530674_1531358_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_005110386.1\|1531435_1531993_+	chorismate mutase	NA	NA	NA	NA
WP_000262548.1\|1532021_1532519_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_001243511.1\|1533115_1533454_+	hypothetical protein	NA	NA	NA	NA
WP_001133114.1\|1534393_1534948_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000527031.1\|1535010_1537248_-	TonB-dependent receptor	NA	NA	NA	NA
WP_000345332.1\|1537697_1538933_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_000179474.1\|1539231_1539483_+	hypothetical protein	NA	NA	NA	NA
WP_001123841.1\|1539895_1540366_+	hypothetical protein	A0A0P0HSF5	Acinetobacter_phage	1.4e-31	45.4
WP_000650375.1\|1540554_1540836_+	hypothetical protein	NA	NA	NA	NA
WP_000825554.1\|1541010_1541394_+	hypothetical protein	NA	NA	NA	NA
WP_000343018.1\|1541678_1542887_+\|transposase	IS256-like element ISAba26 family transposase	A0A218MNI5	uncultured_virus	3.1e-46	46.5
WP_031958126.1\|1543452_1545609_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_001989301.1\|1545916_1547029_+	OmpW family protein	NA	NA	NA	NA
1546364:1546380	attL	NA	NA	NA	NA
WP_000161254.1\|1547208_1547340_+	hypothetical protein	NA	NA	NA	NA
WP_000720299.1\|1547770_1548202_+	hypothetical protein	NA	NA	NA	NA
WP_034129280.1\|1548270_1549857_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1V0SGN0	Hokovirus	3.8e-20	26.2
WP_001109442.1\|1550116_1550560_-	universal stress protein	NA	NA	NA	NA
WP_000774578.1\|1550847_1551075_+	hypothetical protein	NA	NA	NA	NA
WP_034129279.1\|1551253_1551427_+	hypothetical protein	NA	NA	NA	NA
WP_000221476.1\|1551699_1552143_+	RDD family protein	NA	NA	NA	NA
WP_002036117.1\|1552444_1552606_+	hypothetical protein	NA	NA	NA	NA
WP_034129278.1\|1552706_1555463_+	magnesium-translocating P-type ATPase	M1HBF8	Paramecium_bursaria_Chlorella_virus	5.4e-38	25.3
WP_000775740.1\|1555478_1556198_+	MgtC/SapB family protein	G3MA03	Bacillus_virus	2.3e-12	37.8
WP_001169535.1\|1556271_1557444_-	benzoate/H(+) symporter BenE family transporter	NA	NA	NA	NA
WP_000344223.1\|1557630_1558104_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_000467074.1\|1558140_1558791_-	leucine efflux protein LeuE	NA	NA	NA	NA
WP_049592467.1\|1558863_1559853_-	transaldolase	NA	NA	NA	NA
WP_001024732.1\|1559983_1560877_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002010078.1\|1560967_1561402_+	chlorhexidine efflux PACE transporter AceI	NA	NA	NA	NA
WP_000047940.1\|1561468_1563037_-	acetyl-CoA C-acetyltransferase	NA	NA	NA	NA
WP_000132116.1\|1563272_1564664_+	3-oxoacyl-ACP reductase	NA	NA	NA	NA
WP_001097350.1\|1564737_1565592_+	hypothetical protein	NA	NA	NA	NA
WP_000588773.1\|1565663_1566923_+	serine hydrolase	NA	NA	NA	NA
WP_000323807.1\|1566970_1567549_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_049592468.1\|1567673_1569152_+	multidrug efflux MFS transporter AmvA	A0A0M3UL24	Mycobacterium_phage	3.0e-27	26.2
WP_005119983.1\|1569418_1571200_+	metalloendopeptidase CpaA	NA	NA	NA	NA
WP_000739695.1\|1571222_1571837_+\|protease	metalloprotease secretion chaperone CpaB	NA	NA	NA	NA
WP_049592469.1\|1571960_1574033_+	DNA polymerase III subunit gamma/tau	A0A1L2BWV7	Bacteriophage	1.8e-41	31.6
WP_000632984.1\|1574356_1576585_+\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA
WP_000165805.1\|1576633_1577068_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_000017865.1\|1577067_1578225_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_135536659.1\|1578456_1579695_+	lactonase family protein	NA	NA	NA	NA
WP_000388070.1\|1579995_1580499_+	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_005119988.1\|1580518_1581553_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_031958820.1\|1581557_1582688_+	YdcF family protein	NA	NA	NA	NA
WP_001290023.1\|1582687_1583716_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_086225912.1\|1583776_1584280_-	hypothetical protein	NA	NA	NA	NA
WP_000474098.1\|1584336_1585392_-	linear amide C-N hydrolase	NA	NA	NA	NA
WP_169538899.1\|1585602_1587021_-	FMN-binding glutamate synthase family protein	NA	NA	NA	NA
WP_000075452.1\|1587439_1588780_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_000043926.1\|1589391_1589964_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000037347.1\|1590287_1591151_+	iron-containing redox enzyme family protein	NA	NA	NA	NA
WP_049592470.1\|1591649_1592912_+\|integrase	integrase family protein	A0A0P0IKP2	Acinetobacter_phage	3.6e-247	99.3
WP_002055027.1\|1592917_1593187_-	hypothetical protein	A0A0N7IRE8	Acinetobacter_phage	1.1e-41	97.8
WP_000043827.1\|1593187_1593484_-	hypothetical protein	NA	NA	NA	NA
WP_049592471.1\|1593483_1594548_-	hypothetical protein	A0A0D4DBR8	Acinetobacter_phage	2.2e-128	70.1
WP_049592472.1\|1594544_1595666_-	ATP-binding protein	A0A0D4DBX7	Acinetobacter_phage	9.7e-212	99.7
WP_049592473.1\|1595677_1596001_-	hypothetical protein	A0A0P0IRC4	Acinetobacter_phage	3.7e-55	97.2
WP_049592474.1\|1596003_1596444_-	hypothetical protein	A0A0N7IRE9	Acinetobacter_phage	4.1e-73	97.3
WP_002068223.1\|1596648_1597560_-	hypothetical protein	NA	NA	NA	NA
WP_002068240.1\|1597571_1598501_-	hypothetical protein	NA	NA	NA	NA
WP_002068239.1\|1598566_1599226_-	helix-turn-helix domain-containing protein	A0A2H4JAJ5	uncultured_Caudovirales_phage	5.1e-59	73.5
WP_002068237.1\|1599330_1599519_+	hypothetical protein	NA	NA	NA	NA
WP_000041062.1\|1599528_1599885_+	hypothetical protein	J7I452	Acinetobacter_phage	3.9e-58	98.3
WP_001095600.1\|1599940_1600216_+	hypothetical protein	A0A0P0IVP2	Acinetobacter_phage	8.3e-40	96.7
WP_000102848.1\|1600212_1600506_+	hypothetical protein	NA	NA	NA	NA
WP_049592475.1\|1600502_1601462_+	helix-turn-helix domain-containing protein	A0A0P0HSN8	Acinetobacter_phage	4.4e-19	54.4
WP_002048053.1\|1601458_1601575_+	putative phage replication protein	A0A0P0IR92	Acinetobacter_phage	9.8e-11	91.7
WP_002048056.1\|1601574_1601973_+	hypothetical protein	NA	NA	NA	NA
WP_000017820.1\|1601969_1602377_+	hypothetical protein	NA	NA	NA	NA
WP_000778999.1\|1602373_1602772_+	HNH endonuclease	A0A2R2Z2X9	Escherichia_phage	5.8e-26	48.5
WP_001039748.1\|1602768_1602948_+	hypothetical protein	NA	NA	NA	NA
WP_000378367.1\|1602937_1603261_+	hypothetical protein	NA	NA	NA	NA
WP_002125172.1\|1603260_1603656_+	DUF559 domain-containing protein	A0A0P0I8E8	Acinetobacter_phage	5.1e-67	96.9
WP_000783471.1\|1603652_1604153_+	hypothetical protein	A0A0P0IY98	Acinetobacter_phage	2.9e-91	97.6
WP_000508252.1\|1604235_1605000_+	hypothetical protein	A0A0P0IKQ5	Acinetobacter_phage	7.3e-86	91.8
WP_000715267.1\|1605230_1605989_+	hypothetical protein	A0A0P0J0C5	Acinetobacter_phage	5.2e-116	80.2
WP_000787531.1\|1606084_1606732_+	hypothetical protein	A0A0N7IRF1	Acinetobacter_phage	4.7e-126	97.7
WP_000113273.1\|1606779_1607259_+	DUF2280 domain-containing protein	A0A0P0HSK4	Acinetobacter_phage	7.1e-71	95.8
WP_049592476.1\|1607248_1608676_+\|terminase	phage terminase large subunit	J7I460	Acinetobacter_phage	2.2e-261	95.3
WP_049592477.1\|1608672_1610124_+	DUF4055 domain-containing protein	A0A0D4DCP1	Acinetobacter_phage	3.6e-267	93.4
WP_000179752.1\|1610125_1611229_+\|capsid	minor capsid protein	A0A0D4DBL9	Acinetobacter_phage	2.3e-205	99.5
WP_000965231.1\|1611237_1611666_+	hypothetical protein	J7I4P3	Acinetobacter_phage	5.2e-73	100.0
WP_000004365.1\|1611764_1612001_+	hypothetical protein	A0A0D4DC19	Acinetobacter_phage	4.8e-36	94.9
WP_001139861.1\|1612224_1612416_+	hypothetical protein	A0A0P0IKM2	Acinetobacter_phage	1.7e-28	100.0
WP_000770052.1\|1612529_1613297_+	hypothetical protein	J7I0W4	Acinetobacter_phage	1.7e-119	99.6
WP_000214189.1\|1613324_1614281_+	hypothetical protein	A0A0D4DBM4	Acinetobacter_phage	2.1e-178	100.0
WP_049592478.1\|1614347_1615013_+	stress-responsive nuclear envelope protein	A0A0D4DBW4	Acinetobacter_phage	5.5e-114	99.5
WP_031958850.1\|1615017_1615407_+	hypothetical protein	A0A0D4DC24	Acinetobacter_phage	1.8e-64	96.1
WP_049592479.1\|1615408_1615777_+	hypothetical protein	A0A0P0I456	Acinetobacter_phage	1.4e-63	96.7
WP_053094133.1\|1615814_1616525_+	hypothetical protein	NA	NA	NA	NA
WP_049592480.1\|1616574_1616979_+	hypothetical protein	A0A0P0IKR8	Acinetobacter_phage	3.1e-67	95.5
WP_049592481.1\|1616950_1617319_+	hypothetical protein	A0A0D4DBN1	Acinetobacter_phage	7.2e-55	82.8
WP_025469889.1\|1617320_1617719_+	hypothetical protein	A0A0P0IRA6	Acinetobacter_phage	3.2e-69	95.5
WP_000064610.1\|1617787_1618141_+	hypothetical protein	A0A0P0IY61	Acinetobacter_phage	5.1e-58	95.7
WP_049592482.1\|1618140_1619289_+	hypothetical protein	A0A0D4DCQ4	Acinetobacter_phage	2.0e-151	80.5
WP_049592483.1\|1619385_1620303_+	hypothetical protein	A0A0P0IL42	Acinetobacter_phage	7.8e-167	98.0
WP_049592484.1\|1620372_1620888_+	hypothetical protein	A0A0D4DBX8	Acinetobacter_phage	1.4e-77	100.0
WP_000838146.1\|1621213_1621396_+	type II toxin-antitoxin system HicA family toxin	A0A0D4DC32	Acinetobacter_phage	7.4e-29	100.0
WP_000966688.1\|1621488_1621893_+	type II toxin-antitoxin system HicB family antitoxin	A0A0D4DCG1	Acinetobacter_phage	3.9e-70	100.0
WP_000734512.1\|1621992_1622502_+	hypothetical protein	A0A0S0N7I7	Pseudomonas_phage	6.7e-19	35.4
WP_049592485.1\|1622572_1627504_+	tape measure protein	J7I4Q7	Acinetobacter_phage	0.0e+00	86.0
WP_049592486.1\|1627594_1628182_+	hypothetical protein	NA	NA	NA	NA
WP_032002988.1\|1628217_1628694_+	hypothetical protein	NA	NA	NA	NA
WP_000277447.1\|1628754_1629153_+	hypothetical protein	A0A0P0IY66	Acinetobacter_phage	3.5e-71	96.2
WP_046661079.1\|1629152_1629659_+	DUF1833 family protein	A0A0D4DCA4	Acinetobacter_phage	9.1e-93	100.0
WP_000835171.1\|1629655_1630018_+	hypothetical protein	A0A0D4DCJ1	Acinetobacter_phage	2.3e-66	100.0
WP_049592487.1\|1630010_1633457_+	bacteriophage protein	A0A0D4DBG7	Acinetobacter_phage	0.0e+00	96.3
1632519:1632535	attR	NA	NA	NA	NA
WP_002061588.1\|1633525_1633915_+	hypothetical protein	J7I481	Acinetobacter_phage	1.4e-64	96.1
WP_002045818.1\|1633956_1634535_+	chitinase class I domain protein	A0A2H4JDB4	uncultured_Caudovirales_phage	3.9e-79	78.8
WP_005070343.1\|1634638_1635055_-	hypothetical protein	NA	NA	NA	NA
WP_002045824.1\|1635496_1636660_+	glutathione-dependent formaldehyde dehydrogenase	A0A0K0KVL7	Prochlorococcus_phage	5.5e-08	26.5
WP_002061590.1\|1636797_1637544_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	4.7e-13	34.2
WP_025468246.1\|1637621_1638920_-	Y-family DNA polymerase	A0A2H4JBL5	uncultured_Caudovirales_phage	2.2e-154	60.3
WP_049592488.1\|1638923_1639418_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A2H4J538	uncultured_Caudovirales_phage	3.1e-45	59.6
WP_049592489.1\|1639532_1640177_-	SOS response-associated peptidase family protein	A0A218MNF5	uncultured_virus	3.5e-57	48.8
WP_042791638.1\|1640191_1641208_-	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_049592490.1\|1641342_1642053_-	hypothetical protein	A0A2H4JDZ2	uncultured_Caudovirales_phage	8.2e-07	28.0

DBSCAN-SWA_5

2448773 : 2510046

Salicola_phage(14.29%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000471447.1\|2448773_2450138_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_034129560.1\|2450154_2451249_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_086225856.1\|2451272_2453954_-	type VI secretion system ATPase TssH	A0A248SJW6	Salicola_phage	1.3e-81	31.0
WP_000168111.1\|2454173_2454437_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_001072410.1\|2454453_2455221_-	OmpA family protein	NA	NA	NA	NA
WP_000557244.1\|2455223_2456183_-	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_034129559.1\|2456220_2460045_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_031958290.1\|2460075_2461488_-	hypothetical protein	NA	NA	NA	NA
WP_031958289.1\|2461484_2462483_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_031958288.1\|2462446_2464258_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_001047031.1\|2464274_2464751_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000653195.1\|2464830_2465334_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_001066523.1\|2465383_2466865_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_001119042.1\|2466857_2467361_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_000869711.1\|2467377_2468070_-	hypothetical protein	NA	NA	NA	NA
WP_005111318.1\|2468810_2469008_+	hypothetical protein	NA	NA	NA	NA
WP_077109274.1\|2469042_2469747_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	NA	NA	NA	NA
WP_034129558.1\|2470002_2470908_-	sel1 repeat family protein	NA	NA	NA	NA
WP_000523381.1\|2470924_2471707_-	hypothetical protein	NA	NA	NA	NA
WP_002037038.1\|2471710_2472004_-	hypothetical protein	NA	NA	NA	NA
WP_002009182.1\|2472017_2472494_-	hypothetical protein	NA	NA	NA	NA
WP_000864764.1\|2472497_2473274_-	hypothetical protein	NA	NA	NA	NA
WP_034129565.1\|2473275_2476029_-	hypothetical protein	NA	NA	NA	NA
WP_000059480.1\|2476033_2476972_-	hypothetical protein	NA	NA	NA	NA
WP_005120102.1\|2476968_2479599_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.5e-279	54.7
WP_000043351.1\|2479744_2480146_+	hypothetical protein	NA	NA	NA	NA
WP_000542529.1\|2480241_2481186_+	ABC transporter permease	NA	NA	NA	NA
WP_001000083.1\|2481185_2482067_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-38	38.7
WP_000592888.1\|2482118_2483141_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000916852.1\|2483137_2484949_-	allophanate hydrolase	NA	NA	NA	NA
WP_001118705.1\|2484961_2485396_-	transcriptional regulator	NA	NA	NA	NA
WP_001000625.1\|2485400_2485526_-	hypothetical protein	NA	NA	NA	NA
WP_000821714.1\|2485697_2486237_-	hypothetical protein	NA	NA	NA	NA
WP_001140540.1\|2486330_2486678_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_020752994.1\|2486771_2487308_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_031958889.1\|2487346_2490952_-	urea carboxylase	NA	NA	NA	NA
WP_020752992.1\|2490954_2491608_-	DUF1989 domain-containing protein	NA	NA	NA	NA
WP_001090535.1\|2491623_2492364_-	DUF1989 domain-containing protein	NA	NA	NA	NA
WP_001202397.1\|2492678_2493842_-	glutathione-dependent formaldehyde dehydrogenase	E3SJ82	Synechococcus_phage	5.3e-11	26.7
WP_000921222.1\|2494094_2494526_+	SRPBCC family protein	NA	NA	NA	NA
WP_001133101.1\|2494586_2495147_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000343018.1\|2495777_2496986_-\|transposase	IS256-like element ISAba26 family transposase	A0A218MNI5	uncultured_virus	3.1e-46	46.5
WP_000792047.1\|2497115_2497700_-	hypothetical protein	NA	NA	NA	NA
WP_000465117.1\|2497761_2498670_-	sel1 repeat family protein	NA	NA	NA	NA
WP_000698627.1\|2498777_2499998_-	chloride channel protein	A0A1X9I5Z9	Streptococcus_phage	1.2e-32	29.7
WP_031945278.1\|2500301_2502020_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_001211791.1\|2502019_2503603_-	5-oxoprolinase/urea amidolyase family protein	NA	NA	NA	NA
WP_000276200.1\|2503635_2504442_-	putative hydro-lyase	NA	NA	NA	NA
WP_004793259.1\|2504453_2505218_-	LamB/YcsF family protein	NA	NA	NA	NA
WP_001987220.1\|2505252_2506506_-	divalent metal cation transporter	NA	NA	NA	NA
WP_001049899.1\|2506851_2507763_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_086225825.1\|2508046_2508355_-	hypothetical protein	NA	NA	NA	NA
WP_010326927.1\|2509020_2510046_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	8.8e-26	30.7

DBSCAN-SWA_6

2619080 : 2628835

uncultured_Caudovirales_phage(33.33%)

integrase,transposase,tRNA

attL 2615489:2615503|attR 2627006:2627020

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2615489:2615503	attL	NA	NA	NA	NA
WP_000199466.1\|2619080_2621717_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.4e-75	38.6
WP_049581701.1\|2622005_2623214_+\|integrase	site-specific integrase	A0A0R6PDI8	Moraxella_phage	1.4e-107	52.0
WP_053094134.1\|2623241_2624234_+	hypothetical protein	NA	NA	NA	NA
WP_010326927.1\|2624160_2625186_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	8.8e-26	30.7
WP_049592516.1\|2625213_2626272_+	hypothetical protein	NA	NA	NA	NA
WP_049581697.1\|2626285_2626930_+	SOS response-associated peptidase family protein	A0A218MNF5	uncultured_virus	1.0e-56	48.8
WP_000022554.1\|2627039_2627540_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A2H4J538	uncultured_Caudovirales_phage	6.3e-46	57.8
2627006:2627020	attR	NA	NA	NA	NA
WP_006581951.1\|2627536_2628835_+	Y-family DNA polymerase	A0A2H4JBL5	uncultured_Caudovirales_phage	8.2e-154	60.6

DBSCAN-SWA_7

2689825 : 2708395

Acinetobacter_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001136753.1\|2689825_2690281_-	hypothetical protein	A0A0P0HSF5	Acinetobacter_phage	2.2e-53	68.9
WP_000991091.1\|2690736_2691270_-	hypothetical protein	NA	NA	NA	NA
WP_006581303.1\|2691266_2692031_-	ATP-binding protein	A0A0D4DBZ2	Acinetobacter_phage	2.3e-63	47.7
WP_000124477.1\|2692027_2693071_-	hypothetical protein	A0A2H4J580	uncultured_Caudovirales_phage	4.3e-28	52.8
WP_049581661.1\|2693074_2694553_-	DNA cytosine methyltransferase	A0A1I9KFD6	Aeromonas_phage	1.4e-133	53.1
WP_004708298.1\|2694549_2694936_-	hypothetical protein	NA	NA	NA	NA
WP_006581306.1\|2694941_2695502_-	hypothetical protein	NA	NA	NA	NA
WP_000817336.1\|2695546_2696086_-	HNH endonuclease	Q94MV4	Myxococcus_phage	8.1e-31	55.7
WP_000218441.1\|2696082_2696712_-	hypothetical protein	R9VWB9	Serratia_phage	1.0e-29	37.8
WP_000575717.1\|2696708_2697164_-	hypothetical protein	NA	NA	NA	NA
WP_000200037.1\|2697160_2697346_-	hypothetical protein	NA	NA	NA	NA
WP_000290738.1\|2697342_2697543_-	hypothetical protein	NA	NA	NA	NA
WP_000818521.1\|2697576_2697951_-	hypothetical protein	NA	NA	NA	NA
WP_000335919.1\|2697983_2698217_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000550612.1\|2698343_2699033_+	helix-turn-helix domain-containing protein	A0A0R6PCY1	Moraxella_phage	5.0e-25	37.1
WP_000922095.1\|2699044_2699320_+	hypothetical protein	NA	NA	NA	NA
WP_000080848.1\|2699535_2699868_+	hypothetical protein	NA	NA	NA	NA
WP_017815853.1\|2699907_2700711_+	DUF2303 family protein	A0A2R2Z323	Escherichia_phage	6.2e-27	32.3
WP_017815854.1\|2700796_2701057_+	hypothetical protein	NA	NA	NA	NA
WP_001072368.1\|2701115_2701445_+	hypothetical protein	NA	NA	NA	NA
WP_017815855.1\|2701441_2701813_+	hypothetical protein	A0A0D4DCB5	Acinetobacter_phage	6.4e-11	41.6
WP_017815856.1\|2701983_2702664_+	3'-5' exonuclease	NA	NA	NA	NA
WP_017815857.1\|2702676_2703705_+	ead/Ea22-like family protein	A0A2I7QY11	Vibrio_phage	3.8e-13	29.0
WP_000986112.1\|2703842_2704133_+	hypothetical protein	NA	NA	NA	NA
WP_000434519.1\|2704133_2704499_+	hypothetical protein	A0A1B1P9I4	Acinetobacter_phage	3.5e-54	83.3
WP_000655910.1\|2704504_2704792_+	hypothetical protein	A0A0P0J0F2	Acinetobacter_phage	1.2e-36	86.7
WP_000566305.1\|2704788_2705175_+	hypothetical protein	NA	NA	NA	NA
WP_001038567.1\|2705171_2705516_+	hypothetical protein	A0A0P0IYD2	Acinetobacter_phage	1.7e-37	76.8
WP_000417504.1\|2705516_2705768_+	hypothetical protein	NA	NA	NA	NA
WP_001185176.1\|2705977_2707258_+	aspartate kinase	NA	NA	NA	NA
WP_000906487.1\|2707504_2707759_+	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	8.8e-12	66.7
WP_000495834.1\|2707828_2708395_-	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	2.4e-25	42.4

DBSCAN-SWA_8

2871338 : 2886901

Acinetobacter_phage(95.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001019745.1\|2871338_2871884_-	N-acetylmuramidase	A0A0B5L5G7	Acinetobacter_phage	2.1e-95	92.3
WP_001076396.1\|2871982_2872165_-	hypothetical protein	NA	NA	NA	NA
WP_001138125.1\|2872528_2872807_-	hypothetical protein	J7I481	Acinetobacter_phage	9.9e-49	100.0
WP_005120390.1\|2872826_2873342_-	hypothetical protein	A0A0P0J095	Acinetobacter_phage	1.3e-70	94.9
WP_034129526.1\|2873412_2874330_-	hypothetical protein	A0A0P0IL42	Acinetobacter_phage	1.6e-164	96.1
WP_031958899.1\|2875747_2876182_-	hypothetical protein	A0A0P0IVP9	Acinetobacter_phage	1.1e-78	98.6
WP_001136775.1\|2876241_2876697_-	hypothetical protein	A0A0P0HSF5	Acinetobacter_phage	3.5e-83	98.7
WP_000152665.1\|2877358_2877595_-	hypothetical protein	NA	NA	NA	NA
WP_001039309.1\|2877803_2878148_-	hypothetical protein	NA	NA	NA	NA
WP_000861102.1\|2878610_2878865_-	hypothetical protein	NA	NA	NA	NA
WP_001277128.1\|2878836_2879313_-	hypothetical protein	A0A2H4J548	uncultured_Caudovirales_phage	1.2e-25	40.3
WP_000100169.1\|2879309_2879711_-	DUF559 domain-containing protein	A0A0P0I8E8	Acinetobacter_phage	2.6e-66	95.4
WP_032050422.1\|2879710_2880103_-	hypothetical protein	J7HXM5	Acinetobacter_phage	1.2e-07	57.8
WP_000647822.1\|2880095_2880449_-	hypothetical protein	A0A0P0I8A5	Acinetobacter_phage	1.0e-29	55.6
WP_002132664.1\|2880445_2881246_-	hypothetical protein	A0A0P0IDV1	Acinetobacter_phage	3.3e-145	97.0
WP_002132490.1\|2881248_2882130_-	replication protein	A0A0P0IKQ2	Acinetobacter_phage	3.2e-141	99.0
WP_002037796.1\|2882122_2882347_-	hypothetical protein	A0A0P0I444	Acinetobacter_phage	6.5e-35	98.6
WP_002132662.1\|2882418_2882703_-	hypothetical protein	A0A0P0IVP2	Acinetobacter_phage	1.7e-35	89.0
WP_000041062.1\|2882752_2883109_-	hypothetical protein	J7I452	Acinetobacter_phage	3.9e-58	98.3
WP_000165919.1\|2883118_2883304_-	hypothetical protein	J7HXD2	Acinetobacter_phage	1.4e-27	98.4
WP_000792749.1\|2883381_2884146_+	LexA family transcriptional regulator	J7I4M9	Acinetobacter_phage	3.6e-141	98.4
WP_000370480.1\|2884160_2884337_+	hypothetical protein	A0A0P0IKK4	Acinetobacter_phage	1.2e-23	100.0
WP_003113565.1\|2884581_2885085_+	hypothetical protein	NA	NA	NA	NA
WP_002132644.1\|2885081_2885561_+	XRE family transcriptional regulator	NA	NA	NA	NA
WP_002132479.1\|2885571_2885934_+	hypothetical protein	NA	NA	NA	NA
WP_034129527.1\|2886134_2886575_+	hypothetical protein	A0A0N7IRE9	Acinetobacter_phage	4.1e-73	96.6
WP_034129528.1\|2886577_2886901_+	hypothetical protein	A0A0P0IRC4	Acinetobacter_phage	4.2e-51	91.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012008

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP012007

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP012006

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection