CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012152	Anoxybacillus gonensis strain G2 chromosome, complete genome	3 crisprs	DEDDh,cas14j,csa3,c2c10_CAS-V-U3,DinG,c2c9_V-U4,cas3,cas2,cas1,cas4,cas5,cas7,cas8b2	1	4	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012152_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012152_1

692754-692843

Orphan

Consensus_repeat	Method
TATTATATTATATATACTGCCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012152_1

>merge|NZ_CP012152|1|692754-692843|CRISPRCasFinder
TATTATATTATATATACTGCCAATATATAACCTTTTAGAATTATAAATAAATAATACAGTTAAAATATACTATATTATATATACTGCCAA

>NZ_CP012152|1|1|692754-692843|CRISPRCasFinder
TATTATATTATATATACTGCCAA	TATATAACCTTTTAGAATTATAAATAAATAATACAGTTAAAATA
TACTATATTATATATACTGCCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012152.1\|WP_035065087.1\|685305_686403_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP012152.1\|WP_035065126.1\|698574_699729_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP012152.1\|WP_035065098.1\|689289_690159_+\|DUF5309-domain-containing-protein	unknown	unknown	gnl\|CDD\|379950
NZ_CP012152.1\|WP_035065113.1\|695258_696569_+\|phage-portal-protein	unknown	unknown	gnl\|CDD\|377466
NZ_CP012152.1\|WP_035065106.1\|691659_692607_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012152.1\|WP_035065089.1\|686672_686894_+\|holin	unknown	unknown	gnl\|CDD\|378518
NZ_CP012152.1\|WP_035065104.1\|690631_691447_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012152.1\|WP_035065116.1\|697189_697531_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012152.1\|WP_128713014.1\|700794_701658_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379536
NZ_CP012152.1\|WP_035065133.1\|703542_703944_+\|cytidine-deaminase	unknown	unknown	gnl\|CDD\|236225
NZ_CP012152.1\|WP_035065101.1\|690253_690433_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP012152.1\|WP_165569757.1\|691461_691635_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012152.1\|WP_035065129.1\|701768_702830_+\|sorbosone-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|225044
NZ_CP012152.1\|WP_035065093.1\|687245_688499_+\|peptidase-M26	unknown	unknown	gnl\|CDD\|368394
NZ_CP012152.1\|WP_035065119.1\|697687_698266_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012152.1\|WP_035065091.1\|686886_687234_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012152.1\|WP_035065096.1\|688498_688780_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376626
NZ_CP012152.1\|WP_035065110.1\|693545_695147_+\|DNA-packaging-protein	unknown	unknown	gnl\|CDD\|222858
NZ_CP012152.1\|WP_128713013.1\|692993_693341_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012152.1\|WP_081957697.1\|704017_704269_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP012152.1\|WP_035065089.1\|686672_686894_+\|holin	gnl\|CDD\|378518	pfam10960, Holin_BhlA, BhlA holin family. The Phage_holin_BhlA family is a family of holin-like proteins from both bacteriophages and bacterial chromosomes. In bacteriophage, holins are small membrane proteins that accumulate and oligomerize to form non-specific lesions in the cytoplasmic membrane allowing the release of the second protein, endolysins, to access the peptidoglycan. Most holins share common structural features: two or three transmembrane domains separated by a beta-turn, a short hydrophilic N-terminus, a highly charged C-terminus and a dual translational start motif. The BhlA holin of Bacillus is found to be toxic to the host cell where the site of action of is on the cell membrane and causes bacterial death by cell membrane disruption.	0.000172135
NZ_CP012152.1\|WP_035065126.1\|698574_699729_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	8.26578e-53
NZ_CP012152.1\|WP_035065098.1\|689289_690159_+\|DUF5309-domain-containing-protein	gnl\|CDD\|379950	pfam17236, DUF5309, Family of unknown function (DUF5309). This is a family of uncharacterized proteins found in viruses and bacteria.	1.84099e-97
NZ_CP012152.1\|WP_035065113.1\|695258_696569_+\|phage-portal-protein	gnl\|CDD\|377466	pfam05133, Phage_prot_Gp6, Phage portal protein, SPP1 Gp6-like. This protein forms a hole, or portal, that enables DNA passage during packaging and ejection. It also forms the junction between the phage head (capsid) and the tail proteins. During SPP1 morphogenesis, Gp6 participates in the procapsid assembly reaction. This family also includes the old Pfam family Phage_min_cap (PF05126).	3.64638e-52
NZ_CP012152.1\|WP_035065087.1\|685305_686403_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	0.00267558
NZ_CP012152.1\|WP_128713014.1\|700794_701658_+\|hypothetical-protein	gnl\|CDD\|379536	pfam14281, PDDEXK_4, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	6.10245e-05
NZ_CP012152.1\|WP_035065133.1\|703542_703944_+\|cytidine-deaminase	gnl\|CDD\|236225	PRK08298, PRK08298, cytidine deaminase; Validated.	1.77252e-81
NZ_CP012152.1\|WP_035065101.1\|690253_690433_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.39049e-05
NZ_CP012152.1\|WP_035065129.1\|701768_702830_+\|sorbosone-dehydrogenase-family-protein	gnl\|CDD\|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	1.60463e-76
NZ_CP012152.1\|WP_035065093.1\|687245_688499_+\|peptidase-M26	gnl\|CDD\|368394	pfam05342, Peptidase_M26_N, M26 IgA1-specific Metallo-endopeptidase N-terminal region. These peptidases, which cleave mammalian IgA, are found in Gram-positive bacteria. Often found associated with pfam00746, they may be attached to the cell wall.	9.56727e-05
NZ_CP012152.1\|WP_035065096.1\|688498_688780_+\|hypothetical-protein	gnl\|CDD\|376626	pfam01835, A2M_N, MG2 domain. This is the MG2 (macroglobulin) domain of alpha-2-macroglobulin.	3.37917e-05
NZ_CP012152.1\|WP_035065110.1\|693545_695147_+\|DNA-packaging-protein	gnl\|CDD\|222858	PHA02533, 17, large terminase protein; Provisional.	2.53268e-41

>NZ_CP012152.1|WP_035065106.1|691659_692607_+|hypothetical-protein
MMTYTEMEQILQFNDYESKIFMPNEIFSDLQNNIDNPSHIAFAYSYIYFVTWAYRYAKYGIVNELIDQKFIKRILGYNENYKKLDYLIKQNGILEQMDYIRTTKDFPISYSYDEIDGLQFQYVDDFQEYTEYIKALNVPKNFKIKFPIKAFYRDKESEEDNYENGTFFDVERTHLVPFEAFLFCMTNDDLGCTGFYLYAFLRSKAQIFDGYDASIEKLIEHTGIPERTLYRYLDALKKHNMIQCYFDKEFIAGLPKEERRANTYYVNEDHLFSDTVRPYKKRGFKTLKQYEWDKLLEEEMQVQQQMEFLPQKNEN
>NZ_CP012152.1|WP_165569757.1|691461_691635_+|hypothetical-protein
MAKNYFFCYDKRLRDFLRYEKNIDYICEGRHLKTGMIFTLFERTEFLNQALQEYKNR
>NZ_CP012152.1|WP_035065104.1|690631_691447_+|hypothetical-protein
MKKELREKFPNWCSDYTQKQNTLILTDDLDSLVGCAIEKYVKGNEINYFYDFKNIFVADKEDKRKAIGIDLALHKGKSWCNHVVRINENDYVNPLTANINALLKVHAGNYTKKYAMSTTLTMLSFYNLPLPATKEGKMILLAIDSSFLGHYSDAFRKVHNTYLHLLGFDELIDLLNETTKADYLHLQQKYNLKSKIKLNNEGYLETDIALAELQGFFDFPIELPSNKQFSLLAQFKTQDDYTYRIQSKDQIPNLISFALTGTRKMKYTTLC
>NZ_CP012152.1|WP_035065101.1|690253_690433_+|helix-turn-helix-transcriptional-regulator
MNIKLRDEYLLKRRKKGISQKELSQVLQCSQSLLSRYERGECGMKKEKVELYRRYIDQK
>NZ_CP012152.1|WP_035065098.1|689289_690159_+|DUF5309-domain-containing-protein
MFKSTNFTQSELVNLSKEIAVVGVDYTPFTSLLLAKGNTEKATSTIYTWRERSLVHDEDISAVEGEDTTVFTESGRRELNNVLEIFKKGVSVSGTAIAMQSNQLNSEVSDRLLELKINLEKKLINGIKNDGSTTPFKRQMAGLIAFADPTNAVNVTGTVTEDHVKQVMRNLWNQDLAEGQYFALVNADIKEQIDNIYKDRYSYQHKTTNFGLVVDSIETNYGTVNIVLSKHVPADKMVVFNDAYIDLVYLREPAFEPLAKTGDSVKGQVIAEATLKVGSPKAVAVVTVA
>NZ_CP012152.1|WP_035065096.1|688498_688780_+|hypothetical-protein
MALAGDTVRLKCHFRTFDGQLIDPADVKLTIYDSQKQQIEQITLDDTNKEDNGVYFYDYVLPINQSEIIFEFSGVYNNKPILVRDSVKIQFSK
>NZ_CP012152.1|WP_035065093.1|687245_688499_+|peptidase-M26
MLGVGTQSNPYIIQTPQDLHNVRNNLTAYYELGNDIDMSGWGNFTPIGTSSEKFMGNFNGKGYKIKNLTINSTTAYVGLFSFTENATIQNLAIENANVVGQNVNYVGILAGNITNSTIKNCYTTGNVSGQYGIGGLVGWHYSGLIENCFSHANTTGRGRVGGLVGNGATSNSLVNKCYSTGLVTVTPDPNLYNGGLVGSHVDSTKVTNSYFDINTSGQTISAGGTGKTTAEMKQQTTYVGWDFTNTWGINNDYPYLQIFGVPTAPPKKETITIQSYVNHIHSKTSKINKSTKQTQSFLNTIQTLSERHTSTKRTISSYTLPNATSVQKQNRTVRSVTQHVTSYMNPIDSIVERKTKTIQQLLSYINHIKSNVIAVAPIQNKIVNASVYVIENTSTVQFEDNLSNTYAIENPSVVEVI
>NZ_CP012152.1|WP_035065091.1|686886_687234_+|hypothetical-protein
MAEITSSAYQAIRDYIQANWQYIELRDDLGNPILRLSPSDSRVTSTIEGQTVKLQIVVKGSDADITKPQTFASSAIYDVATGGQPYSIESFTSFTIESDMDELTVIHEIQVPQVV
>NZ_CP012152.1|WP_035065089.1|686672_686894_+|holin
MDLTSIPIEQFVSNGVFATLFVWLLIDTRKESKEREQKLLEQIEKQNEAQERIVQAIERIEKKIEKMEVSMNG
>NZ_CP012152.1|WP_035065087.1|685305_686403_+|sigma-70-family-RNA-polymerase-sigma-factor
MKKKTLRDWIVEYRKNKEVMSDFIVEYVEKEKNELGQWDEIRYIRTQDKALNQIMKRIEARYCYRNAIDKKDMNEYFLNALYEIFEKVDIKRSPSEIISWAGEKMNFVVIEHIRTQYDTEILSENEIVYNTENEDEVNISDVQIYRDWLKDEDANTYKKFLKFVGGLENILSDAQFEIYTYIKSGKTQQEIAEKVNVSQQYISKTLNAALNRIKAEYLAFRTYKIIVKTNTYQTIKTFVKYTENILEHVIDDEAMLFTYIVNFLKENDEDDISIESAHENKRDINTTVIDALFDYMSEKDAKWFIERWKGEKEVKTQKDKQRFVRIVNKSFMQYLIKSKEALKEMSEHIVEKGKENYNDIIELIS
>NZ_CP012152.1|WP_128713013.1|692993_693341_+|hypothetical-protein
MRKFQIRTAKNAHILSMSDEEFLQWADRKSMIVFQNWEQTDEYFELYMLYMKRKMQRDLETVYDVVSEKAKQGDEKAVKLFLQLHKDMAQLQKSMNRTQTKQEEVQEDEDDDLVL
>NZ_CP012152.1|WP_035065110.1|693545_695147_+|DNA-packaging-protein
MTKRLSKEEKIKIIMSDFKLFAKNFIKIIDNNGDTVPFVLNPEQEEFIKNMEKYNIILKGRQIGFTTLSLAYMLYSACTKPDTNYIIMTHHASVSKSLFVKLKKMYKNLPHDKYPNLFPKTLLNNREELYLDNGSRIIIATAQGEDAISGNSFQMIHLSEMAKYPADVQEEIIATCIPALAKNESSAIIIESTAFGYNTYQEMFMKAYRDKESVWKAHFYSWLAKAYQSQFKHTFDEAEVWFKTNNNGRRMTYDDLEHDEKVLRDKYGATYRQLMFRRYYIATNSLEKFRREFPTTPDEAFVESNKSIFDTNKIIERLQYVIPALETKEVYDVLPDALKPYLNKNLFIYHLPKQKIRHYAGVDVSSGQGGDYSTMSIFDVDGQQVASFFANDIPVYKFAEIVNELGRFYNYAFTAVERNSYGLPLLERLRKEYGYMNLLKQKVFDQKGKRKMQLGFQTTNVTKPIIINDMKEAFELGMINIECVRTLEEMKIYQEQKNGKMGNKKGKSNFDDLVISVAMAVQAMKQAKYYVDI
>NZ_CP012152.1|WP_035065113.1|695258_696569_+|phage-portal-protein
MNLQQYIKEYHEGRSDWFIEEVQSVSNQQRVMNVLNLKDYLDGKHKILQKPNEKFAGKEYVPRKIVLNHALTLLNFQTSFLLQNPVTITGKERIVKEYQKVNRQGKYDRLNYRILDKMLKYGQVYEYVYLDKNTIKSKLIDASEGYPIYNHDNEMIAFVQAYMVDGIDYYVVYSDDVVETYNNKGGQLRMTGRYANLSGLPIVYKTTNEVNENEGKSELENWISILDSLEDLISKATDAYYKFITGIPVVTGQQLKGEGLPIDVIGVGLNLDDGATFEFVSNKFDSNAFDTLYETLLNALYTVAHLPAIAVGRTDISNVSTEAVRILYQLAMMKAGQNEQFMREGIEQRFEKIRKLLEYKGVTFSDDEFDSLGLVFQYALPSNDREIIENMKALREIGGLSLQTTLEQNPYVHDVQQELIRLKEENNTTYSSRFDN
>NZ_CP012152.1|WP_035065116.1|697189_697531_+|hypothetical-protein
MTNLQRLLLEVQGINLDQNELAVYLQENELQPFDEYNPSSATAKRNIYKTALSILESIANNVQLMKNYKHDDMTVTDFHENLLNRIDQLERKIRSMKTDEENQQGNVFMLFNS
>NZ_CP012152.1|WP_035065119.1|697687_698266_+|hypothetical-protein
MNPFTFDTSDFQFLIDTVGETVTIDNVSKKCIVQNVKIGDYEDKYIYTLDSIQRGNLILHNRKNYLIISDVTEGKQYKKALMRKCTHTIRVMIQEGQQILTGTTPWGEEQYETTDPIYEDFPCIVEQQKVVIDGGAIRTADTEILITLQDNENTRKVKVNDEYDIAGYRYKVTHINYTKTGLLILKCETAVA
>NZ_CP012152.1|WP_035065126.1|698574_699729_-|site-specific-integrase
MMNFDKLIKEKKKGFYFRIDVGKDPVTGKRKQASFGPFRTKTEAKKELLKIKAQVDDGSYFKESTEDFPMFMERWFNTSYKRTVEITTAKSREYVIRNHIMKYFQHKKINEITTFDIDSFYVDKLDNGYSGAYIRQMHNLLNQAFDQAVRWSLVKVNPVKNAKPPKVKSEEKITWTVDEVNRFLNLIKNSSMEIPYLLAIFTGMRRGEVLGLKWDDVDFENKKIRIKRSLCFVSGKGLIFKEPKTKKSKRQISISQHVVDVLKKHKQKQEFQKEKLGVQYQDNNLIVCTDDGKPLDPRNLLRQFYRLIEEANVPRISFHDLRHTHATILMQQGENPKVVSERLGHSRVGITLDLYSHVSDDLQEQAAEKFENALLKQSQNPLVD
>NZ_CP012152.1|WP_128713014.1|700794_701658_+|hypothetical-protein
MMNRPNLFSYGTSELSQDAFLCWLMDWANPQFSALDPNLHHIGKKFIEAIFKKHQQPVPTIENVSIIKQLDGLDILAVINDKYAILIEDKTYTNDHTNQLIRYCEAMKKRGYNYQLPIYYKIGNQSSFHTVETAGYKPFLRQDMLAILHEGYKLNIKDTIFNDYYQHLLSIDKAFNKYKTHPLNKWEELSWQGFYSELQKKGILGDWDYVSNPRGGFYGFWWNWGGNDECRQYLQLEQEKLCFKIEVSNKEKRSQLRSTWCQKILEKSRDFQLPVKRPSRFGNGKLF
>NZ_CP012152.1|WP_035065129.1|701768_702830_+|sorbosone-dehydrogenase-family-protein
MTKYPLIMISIIFLLTGCLKQEENSPQNVQQTNNNINMEIIAQDLSVPWAIDWDGTSFYISERTGFIVKITGDEKIRQNLHLEKKLSTAAEAGVLGFALHPEKKNYAFLYYTYEDENGQFNRVVEIREENNEWFEQKVLLDRIPSGNFHHGGRIKIGPDKKLYITTGDATDSMIAQDKTSLGGKILRMNLDGTIPDDNPYSSSLVYSYGHRNPQGLAWDETGQLYSSEHGSSAHDEINLIKPKGNYGWPLIQGDEMKDGMIAPLFHSGILTWAPSGIAYHNGILYVAQLRGEGVLAFDLKNKTYKQIVSNVGRVRDVFILGDHLFFVTNNTDGRGIPANHDDKLIKIPIPKAF
>NZ_CP012152.1|WP_035065133.1|703542_703944_+|cytidine-deaminase
MNIEQKLYQAAIDLIEKRYPSGWGGAAAMYTEDGQILTSVSPDVINASTELCIETGAILEAHKLNTKVTHTICVVREDENAEFKVLTPCGVCQERLFYWGENVKAAVTNPNDKLDYKTLKEIQPHHWYKAYDK
>NZ_CP012152.1|WP_081957697.1|704017_704269_+|hypothetical-protein
MINAYNTLVAIFLLILLNVQIIAEIPVFDISYIWISLFGMLICLLGLIKQDRFYSYLGGILHFILIVSCMGMILFGIGINYKP

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Crispr_ID: NZ_CP012152_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012152_2

724013-724309

Orphan

Consensus_repeat	Method
GTTTGTATCGTACCTATGAGGAATTGAAAC	PILER-CR
GTTTGTATCGTACCTATGAGGAATT	CRISPRCasFinder
GTTTGTATCGTACCTATGAGGAATTGAAAC	CRT

4 spacers

The CRISPR arrays of NZ_CP012152_2

>merge|NZ_CP012152|2|724013-724309|PILER-CR,CRISPRCasFinder,CRT
GTTTGTATCGTACCTATGAGGAATTGAAACAAACGTTTGATTCAGACGTAAATGAAGTGACTCGCGCGGGTTTGTATCGTACCTATGAGGAATTGAAACTCTCAAGCTTCTTCCAGTCAAACAACAGGAAAATAGTTTGTATCGTACCTATGAGGAATTGAAACTACATGCTTTTCACCTCAAATGAAAAACGCCACCCCAGTTTGTATCGTACCTATGAGGAATTGAAACATTTACATTTTCCGCATTTTCGTTTTTATTTTCTTTGTTTGTATCGTACCTATGAGGAATTTCTCC

>NZ_CP012152|2|1|724013-724243|PILER-CR
GTTTGTATCGTACCTATGAGGAATTGAAAC	AAACGTTTGATTCAGACGTAAATGAAGTGACTCGCGCGG
GTTTGTATCGTACCTATGAGGAATTGAAAC	TCTCAAGCTTCTTCCAGTCAAACAACAGGAAAATA
GTTTGTATCGTACCTATGAGGAATTGAAAC	TACATGCTTTTCACCTCAAATGAAAAACGCCACCCCA
GTTTGTATCGTACCTATGAGGAATTGAAAC

>NZ_CP012152|2|2|724013-724304|CRISPRCasFinder
GTTTGTATCGTACCTATGAGGAATT	GAAACAAACGTTTGATTCAGACGTAAATGAAGTGACTCGCGCGG
GTTTGTATCGTACCTATGAGGAATT	GAAACTCTCAAGCTTCTTCCAGTCAAACAACAGGAAAATA
GTTTGTATCGTACCTATGAGGAATT	GAAACTACATGCTTTTCACCTCAAATGAAAAACGCCACCCCA
GTTTGTATCGTACCTATGAGGAATT	GAAACATTTACATTTTCCGCATTTTCGTTTTTATTTTCTTT
GTTTGTATCGTACCTATGAGGAATT

>NZ_CP012152|2|1|724013-724309|CRT
GTTTGTATCGTACCTATGAGGAATTGAAAC	AAACGTTTGATTCAGACGTAAATGAAGTGACTCGCGCGG
GTTTGTATCGTACCTATGAGGAATTGAAAC	TCTCAAGCTTCTTCCAGTCAAACAACAGGAAAATA
GTTTGTATCGTACCTATGAGGAATTGAAAC	TACATGCTTTTCACCTCAAATGAAAAACGCCACCCCA
GTTTGTATCGTACCTATGAGGAATTGAAAC	ATTTACATTTTCCGCATTTTCGTTTTTATTTTCTTT
GTTTGTATCGTACCTATGAGGAATTTCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012152.1\|WP_035067761.1\|725851_726274_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240054
NZ_CP012152.1\|WP_049720865.1\|723172_723619_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|307170
NZ_CP012152.1\|WP_035067772.1\|718435_718834_+\|Hg(II)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|131106
NZ_CP012152.1\|WP_035067776.1\|713204_716159_+\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NZ_CP012152.1\|WP_035067483.1\|728876_729392_-\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP012152.1\|WP_035067478.1\|730293_732024_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP012152.1\|WP_035067476.1\|732017_733814_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP012152.1\|WP_035067759.1\|726639_727893_+\|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl\|CDD\|379536
NZ_CP012152.1\|WP_049720866.1\|723617_723797_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012152.1\|WP_035067774.1\|717235_717964_-\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|307807
NZ_CP012152.1\|WP_035067763.1\|724984_725497_-\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP012152.1\|WP_035067472.1\|735559_736294_+\|metallophosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|378975
NZ_CP012152.1\|WP_035067768.1\|722576_722849_-\|DUF3986-family-protein	unknown	unknown	gnl\|CDD\|372497
NZ_CP012152.1\|WP_035067766.1\|724454_724892_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP012152.1\|WP_035067778.1\|710501_711986_+\|type-I-restriction-modification-system-subunit-M	unknown	unknown	gnl\|CDD\|223363
NZ_CP012152.1\|WP_035067481.1\|729406_729937_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_CP012152.1\|WP_049720863.1\|711975_713208_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341134
NZ_CP012152.1\|WP_035067781.1\|719183_720833_+\|mercury(II)-reductase	unknown	unknown	gnl\|CDD\|273944
NZ_CP012152.1\|WP_035067474.1\|734571_735405_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP012152.1\|WP_035067785.1\|716207_717188_+\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|226612

Protein	Function_ID	Function_description	E-value
NZ_CP012152.1\|WP_035067483.1\|728876_729392_-\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.94568e-36
NZ_CP012152.1\|WP_035067763.1\|724984_725497_-\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.28605e-34
NZ_CP012152.1\|WP_035067772.1\|718435_718834_+\|Hg(II)-responsive-transcriptional-regulator	gnl\|CDD\|131106	TIGR02051, Mercuric_resistance_operon_regulatory_protein, Hg(II)-responsive transcriptional regulator. This model represents the mercury (II) responsive transcriptional activator of the mer organomercurial resistance operon. This protein is a member of the MerR family of transcriptional activators (pfam00376) and contains a distinctive pattern of cysteine residues in its metal binding loop, Cys-X(8)-Cys-Pro, as well as a conserved and critical cysteine at the N-terminal end of the dimerization helix. [Cellular processes, Detoxification, Regulatory functions, DNA interactions].	2.81617e-62
NZ_CP012152.1\|WP_035067776.1\|713204_716159_+\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	0
NZ_CP012152.1\|WP_035067478.1\|730293_732024_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.31708e-161
NZ_CP012152.1\|WP_035067476.1\|732017_733814_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP012152.1\|WP_035067759.1\|726639_727893_+\|PD-(D/E)XK-nuclease-family-protein	gnl\|CDD\|379536	pfam14281, PDDEXK_4, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	1.10979e-28
NZ_CP012152.1\|WP_035067761.1\|725851_726274_+\|NUDIX-domain-containing-protein	gnl\|CDD\|240054	cd04699, Nudix_Hydrolase_39, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	9.64616e-28
NZ_CP012152.1\|WP_035067774.1\|717235_717964_-\|M48-family-metallopeptidase	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	4.22833e-62
NZ_CP012152.1\|WP_049720863.1\|711975_713208_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341134	cd17245, RMtype1_S_TteMORF1547P-TRD2-CR2_Aco12261I-TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Thermoanaerobacter tengcongensis S subunit (S.TteMORF1547P) TRD2-CR2 and Aminobacterium colombiense DSM 12261 S subunit (S.Aco12261I) TRD1-CR1. The S.Aco12261I S subunit recognizes 5'... GCANNNNNNTGT ... 3', while the recognition sequence is undetermined for S.TteMORF1547P TRD2-CR2. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. S.TteMORF1547P TRD1-CR1 and S.Aco12261I TRD2-CR2 do not belong to this family. This family may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	1.1347e-97
NZ_CP012152.1\|WP_035067472.1\|735559_736294_+\|metallophosphoesterase-family-protein	gnl\|CDD\|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	6.43507e-20
NZ_CP012152.1\|WP_035067768.1\|722576_722849_-\|DUF3986-family-protein	gnl\|CDD\|372497	pfam13143, DUF3986, Protein of unknown function (DUF3986). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length.	1.94361e-28
NZ_CP012152.1\|WP_035067766.1\|724454_724892_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.54616e-19
NZ_CP012152.1\|WP_035067778.1\|710501_711986_+\|type-I-restriction-modification-system-subunit-M	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	5.41351e-149
NZ_CP012152.1\|WP_035067481.1\|729406_729937_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	5.94391e-13
NZ_CP012152.1\|WP_049720865.1\|723172_723619_-\|DMT-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	1.01044e-13
NZ_CP012152.1\|WP_035067781.1\|719183_720833_+\|mercury(II)-reductase	gnl\|CDD\|273944	TIGR02053, Mercuric_reductase, mercury(II) reductase. This model represents the mercuric reductase found in the mer operon for the detoxification of mercury compounds. MerA is a FAD-containing flavoprotein which reduces Hg(II) to Hg(0) utilizing NADPH. [Cellular processes, Detoxification].	0
NZ_CP012152.1\|WP_035067474.1\|734571_735405_+\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.15551e-71
NZ_CP012152.1\|WP_035067785.1\|716207_717188_+\|restriction-endonuclease	gnl\|CDD\|226612	COG4127, COG4127, Uncharacterized conserved protein [Function unknown].	4.78556e-73

>NZ_CP012152.1|WP_049720866.1|723617_723797_+|hypothetical-protein
MHNRSPCFIGIEGEHYRTIGIAATSFFHLSPAAKMFIRCLFQWLTEQALLDFPAERYFR
>NZ_CP012152.1|WP_049720865.1|723172_723619_-|DMT-family-transporter
MLAAVSYAAHIVVTGQLTKHSDSIALGILQLSACGIISLFVSLWLESPTVPTSSAWVAIVALGILCSAIRLVVQTVAQKYTTATHAGLIFSLEPVFAVLFGYLFLGEVLSIKGYIFWHFIRRNAAETCKAIRAICRIKKLTCRQLVTV
>NZ_CP012152.1|WP_035067768.1|722576_722849_-|DUF3986-family-protein
MKFDPNQHLHLGYYENNVDLEAVAYKIQNENKWVVFLDNEQNTTLVKKILDKYDFHEKYGYKIFTVDADDLSYEVGSKLFEEWLKANNII
>NZ_CP012152.1|WP_035067781.1|719183_720833_+|mercury(II)-reductase
MRKYRLQVEGMTCTGCERHVETALNSIGAKNVDVNFRRGEAVFELPEHIGIEKAKEAVNKVNYKAGEAEVIHQQKSSVVGDDEGDYDYDFIVIGSGGGAFSAAIKAVEYGAKVAMIERGTIGGTCVNIGCVPSKTLLRFGEINHLAKNNPFLGLNTSAGSVDLKKLMEQKDELVRELRQQKYVDLIDEYGFELIQGEAKFVNEKTIEVNGNKITAKRFLIATGASPLIPNIPGLKDVDYLTSTSLLELKELPKSLAVIGSGYIGLELGQLFHHLGVEVTLMQRSQRILKEYDPEISESVEKALTEQGIHVITGATFERVEQNGDMKQIHVTVHGEKKIIEAEQLLVATGRKPNTEALNLQAANVEVGSRGEVKVDDYLRTSNPRIYAAGDVTMGPQFVYVAAYQGGIAADNAIGGLERKVNLDTVPAVIFTSPSIATVGLTEEQAKERGYEVRTSVLPLDAVPRALVNRETTGVFKLVADAKTLKVLGVHIVAENAGDVIYAATLAVKFGLTVEDLRECLAPYLTMAEGLKLVALTFDKDVKKLSCCAS
>NZ_CP012152.1|WP_035067772.1|718435_718834_+|Hg(II)-responsive-transcriptional-regulator
MKYRIGELADKCNVNKETIRYYERKGLIKETSRTDSGYRMYSEETVKRIGFIKRMQELGFSLSEIHKLLGVVDKDEVRCADMYSFVSQKIGEVQQRIKDLKRIENMLNKLKESCPNEEQLHECPIIESLIDD
>NZ_CP012152.1|WP_035067774.1|717235_717964_-|M48-family-metallopeptidase
MPSFQYGKTTIDYAVEYKPEKRDVTISVEWLEGVKVVAPEGIEPTLLHSILYKKAPWIIDKWQALNQISDCPAPKEFVSGEKFAYLGRNYRLKVYKSEEVTKPVLMFKQGKFIATVPPHLTEEERISFFQQAFKDWYILYGEMKLQERLKIYCPKMGVTPTKIKLKEQKMRWGTCTNEGAIYLNWRIMMAPMPIIDYLLVHELAHLKYPNHSNDFWHFVKSVMSDYEQRKEWLRVNGPTLTL
>NZ_CP012152.1|WP_035067785.1|716207_717188_+|restriction-endonuclease
MMKWWMVRAGDQNELIPFWKQKGVASIGWAEFGDPKNYSTREALIEKAHKIYEEEKPATRITWASQVWRFSREIKVGDRIITYAKDKREYLIGTVTKEHEYNETIVSEYYPNVIHIKWEKKQIPRDQLSQGAKNSLGSTLTVFRVDDWGEELERLLAGEEPVVSEPEDNEEEVIKEDFVQKALTMIQDKVDKLDPWQMQELVAGLLQAMGYNVKVSKKGPDGGVDILAHKDAFGFEKPIIKVQVKHRKSASSGPEVQQLLGAHPIDANSLFVSTGGFTTAAENIGKQHNVKLIDLEELVNLIVQWYDRMPNETRSLLPLQKIYIPE
>NZ_CP012152.1|WP_035067776.1|713204_716159_+|type-I-restriction-endonuclease-subunit-R
MTTSSEWNELNLVEKRLINQLQELGYEHVTGLALESERDSLSEVILKERLKKAIQRLNPWIDENNLARIIYNLTHIEATGLMQANEKFHEMLVNYISIQQDLGKGKKNQTVKLIDFDNPYNNEFLVVDQFRIQDARGTIRPDVVIFVNGLPLVVVECKSPTLQEDTQISKAVNQLRRYQETHEQLFYYNQFMIATSNYRAKAGTIGAKVQHFSEWKDPYPRTVPELGDSPTKQDILVAGMLAKENLLDLIQNFIVFEVDGGRVIKKIARYQQFRAVNKAIHRILHAKTPKDRGGVIWHTQGSGKSLTMLYLAVKLRRIKELHNPTIVVVTDRKDLDDQITKTFRKCGFPNPQQAESVKDLKRLLQQGPGSTIMTLVQKFQPDKDQDEYPELSRSENIFVLVDESHRTQYKGLAMNMRKGLPNACYIGFTGTPIDKEDKSTTRTFGSYIDKYTIEQAVDDGATVPIFYEARMVDLHLQGESLDRLFDRKFSDYSEEDRERIKKKYANEEAILAVPSRIGKIALDIVEHFENYILPNGFKAQVVAVNREAAAIYKQKLDELINGKYETALIISTGPEDKNNELLKDYSLSREEEKQLIERFKKPFEEDKLAILIVCDKLLTGFDAPIEQVMYLDKPLKEHNLLQAIARTNRTYEGKTYGLIVDYFGVSKFLEKALAIFSKQDIQGALLPIESELPKLKQAHRKAMSFFDYINRSDADACVQVLEPEDVRHEFEKAFKEFSKRMDMILPNPEASPYVEDLKFLGKVRQMAKTLYRDEQMDISECGEKVKQLIAEHLYAESVEVIHEPIDILSSKFDERLEKAPSKEAQAAEMEHAIRHEIKVKLEENPVYYTSLREKLEQLIEARRKKMMDIAELVEKLRSMVNDMRNVNQQAQNLGFTREQYPFYQLFQQILPDEEHKDTIDALTHLVTDMIAEESQVIDWVNKEDVKREMRKKIKKQLRASVIPKDQIENITQQIMSLAMVHYKK
>NZ_CP012152.1|WP_049720863.1|711975_713208_+|restriction-endonuclease-subunit-S
MVSEWKNAFLSEVAEITMGQSPASSDCNEYGEGLPFYQGNAEFGYMYPIPKRYCVKPKKVAEAGDILISVRAPVGDVNIAQEMSAIGRGLSAIRPTNVEKMFLFYFLQHFKPKWATLQQGSTFEAINKNDLSNLEIPTPPLREQRKIAAILSSVDEAIEKTEAIIEQTEKVKKGLMQQLLTKGIGHTKFKKTEIGEIPEAWAVEELSNLTLKIQDGNYGNDYPKENEFLSQGVPFLTSAAIGNTNSIDHKKVKYISFEKHELLRKAHIKTKDILFTNRGANVGAVAIVSERYNNANIGPQLTLIRSNPDRVHYVYLYYYFQTSYIKKEIRKHDSGSAMNFFSIGTTKKFKIVVPPLEEQLKISEVLQTIDKKIIMEKRKLSELQDIKAGLMQVLLTGKVRVKVDNEVMSQ
>NZ_CP012152.1|WP_035067778.1|710501_711986_+|type-I-restriction-modification-system-subunit-M
MSKLTLQELESHLWESANILRGSIDSSDYKNYIFGMLFLKRLNDVFVETAERIEKEEGEDYGWYDRDEHQFFVPEKARWSYIQSHSQDVGAVINKAFELLEDENPSLQGVLANIDFNDKEKLSDKTILQLVQHFSQIDLRNENLSEPDILGRAYEYLIKQFADDAGKKGGEFYTPSQVVKLIVKLIKPEEGMRVCDPTAGSGGMLIQSVDYIKEKGGNPRNITLHGQEKNLNTWAICKMNLLLHGLSDHEIKKGDTIREPKLLDENGELLLYDRVIANPPFSLKNWGREEAEADAFNRFRFGLPPKNAGDYAFIQHMIATLNDEGKAGVVMPHGVLFRGGAEGKIRQGILEEDLIEAIIGLPANLFYGTGIPACILIINKNKEEHKKGKVLFIDASNDYQEGKNQNVLRDEDIQKIISTYDAWKDVDKYSRVVTLEEIKENDYNLNIARYIDTIEEEEEIDVAEALRKLRQLEQERDEIEKVMYGYLKELGYGE
>NZ_CP012152.1|WP_035067766.1|724454_724892_+|GNAT-family-N-acetyltransferase
MEIRKPNDSEYKKILSLSPQALFEGTLGEAKPSDEKVKQLIEPLLQKGSYYLIATEGDNLIGWILIGTSKDQFTGKIYGFIYELFVLEEFRGNGISKQLMETGIEHLKQDGYSEVRLSVYAGNQAIKLYEKLGFKNRTITMSMNI
>NZ_CP012152.1|WP_035067763.1|724984_725497_-|IS630-family-transposase
MFYVDETHVRAYQALRTTWAEVGNQKQVPRYGHHDHVSIFGAVDVQQGDVVFHRASSANAETFLDFLRRLKEKYADRFLVLVLDNARIHHTKMVQAFLDGEEGAAFHFIFFPPYSPQLNPIERLWKWLKDEVIANVFHKDQNDIAQSITRFEQYVLQHPDEVLRRMGCAV
>NZ_CP012152.1|WP_035067761.1|725851_726274_+|NUDIX-domain-containing-protein
MTSLNEIVVVLKGFILHKGKVLMVQRAHDDEVGGGTWELVGGQIRFGEDLETALLREIQEEVGLDVTVERILYATTFQTHATRQVVILTYLCKSDHHEVFLSQEHIDYRWSTKEQSRELLPPAILHDFERNDVFSLEEWV
>NZ_CP012152.1|WP_035067759.1|726639_727893_+|PD-(D/E)XK-nuclease-family-protein
MQLNTEERERLVQQITRFVSNNDLLEKLNAKLNEFNPFEVLKVTHHEIRHSNVLSWLLHPKESHFMGDYFLKKIISEVLCGDVVRKNHSLQITDILVNDFHDAEVFREWRNIDLVIISKKNSFVLFIENKVHAGLASHQLEKYLETIKQTFPTMKHIVPVFLTLNSDEAPHDEYYSLSHSQILNILKLALEMYKDRMSNKIYDFIYYYIRTLEDLTMQDEQLIALCSEIYKQHKEAIDAIVKYGMVLNSSLHQAVEKLKENNNLDIIDSTQDNRFFKNDKELWFIPTFLAKNLPSLIRKWKSPFPVAYFFVREEKKLRLILEVGPIQDGQIRLQLLNEIVKHNSQLFSAKSSALTNVNGTFTRIRHSSIDITDWNDIDYLSERINDFLVNDFKYDEVNKVLMDILQNYDSSKIGQQI
>NZ_CP012152.1|WP_035067483.1|728876_729392_-|IS630-family-transposase
MLFYVDETHVRAYQALRTTWAEVGNQKHVPSYGHHAHVSIFGAVDVQQGDVVFHRASSANAETFLDFLRRLKEKYTDRFLVLVLDNARIHHAKMVQAFLDGEEGAAFHFIFFPPYSPQLNPIERLWKWLKDEVIANVFHKDQNDIAQSITRFEQYVLQHPDEVLRRMGCAV
>NZ_CP012152.1|WP_035067481.1|729406_729937_-|helix-turn-helix-domain-containing-protein
MKRLKITNDHGWTPRTLRKQERKIKDASLRVRVTAVRLVMEGHLGKDVAKMVNVCRQSVALYVARFNQGRLDHLLDRRLPPGRVPFLTEEQQQEIRQLVLTTTPVDAGWGIASSWNTRILQSYIQQTYGVSMSREGIRKLLHRLRLSWTRPTYKLVKGDAKRQAAFQRELEFIKKN
>NZ_CP012152.1|WP_035067478.1|730293_732024_+|ABC-transporter-ATP-binding-protein
MFGVLAYLKPYTKWMILAWGLMLIELATELWHPLLMAKIIDDGILQHDFSVVWKWGSIMMSTSLIAFMAGIANSFVAAYVGQNYGFALRNRLFEKVQSFSFSNFHQFPTSSLITRMTNDVTQIQNTVFMSLRIMLRAPLLVLFGTVMALYVHFKLALILVFTVPILLLFLIWMMNKGMALFKMVQQKLDQVNEVMRENLTGMKFIKAMMRGEHEQRRFTKVNEDLMNRTIRSLQTMELSMPVLLFVMNIAIILILWFGDINIQIGSAKAGEVVAIVNYATRITSALSIFTFILIVFSRAKASARRVSEVLAVNIDLSDREETNYETTIKEGKVIFEDVHFQYSNSQVPVLKNISFIAHPGETIAILGATGSGKSSLLQLIPRLYDVNKGRVLIDGIDVRDMNQEMLRKQIGFVPQEVLLFSGTVKENIAFGKEDASMEEMIEAAKHAQIHETIMKLPNGYDTIVGQKGVNLSGGQKQRLSIARALIRKPKILLLDDSTSALDLKTEAELLKSLKSYTCTTFIVTQKVSTAMKADTILLLDEGALLAKGNHECLSKSCALYQKIVQSQLNSEEKYIC
>NZ_CP012152.1|WP_035067476.1|732017_733814_+|ABC-transporter-ATP-binding-protein
MLRPQHHWKKTSEQKANKLFRTLKRIATLLSKQKGMLALVLLMVVFSSFLSLFGPYFIGKIIDEHIVVKKQDGLIQSLMILGGVYLFLSLSLFLQNYWMIAIAQKTVYSLRKQLFEKFHKLPIRFFEERQHGELMSRITNDIENVSQTLNSSIIQLFSSTLTLVGAVIVMVSLSPLLTVLTLTIVPMMFFGMKWITNRTRMLFKEQQRNLGELNGFIEESISGQKIIKMFSQERQTISEFQRKNEKLKQSGFWAQTYSGFIPKLMNVLNNISFAIIAGIGGVLALKGLISIGVIVIFAEYSRQFTRPLNDLANQFNMLLSAMAGAERVFEIIDMEEEEDEKEAVHLRNIKGEVEFHHVSFSYEKSRETIQDIHFRVSPGETVALVGPTGAGKTTIINLLSRFYDPDSGQVFIDGYDIKHIKRASLRQHMAFVLQDTFLFQGTIRENIRYSRLDASDKDVEEAAKLANAHSFIMKLPNGYDTVLNEEGSGISQGQKQLLAIARAILANPSILILDEATSSIDTVTELKIQEALQRLMKGRTSFVIAHRLNTIRNADQIIVLHEGRIVEKGTHHSLLKAKGFYYELYHAGTDQFNISRGR
>NZ_CP012152.1|WP_035067474.1|734571_735405_+|pirin-family-protein
MKAQRGIRRIKTVQYQTNSPIHQNGFVLEPGNWQEYDPFLMLAEDFFQRGTFDLHPHRGIETVTYVIDGVLEHFDNKAGYGKLEPGDVQWMTAGRGVIHKEDPAPGSTVHSLQLWINLPSSKKMTEPRYQNLKSKDMPVRKEEGAIIRVFSGSSKGVQASTLNHVPVTMVEMLLEPGASVVQDLPGSYNGFLYILEGSGTFGIDETEGHKGQVLFLSSADGASESEIKITAKEKLRILLYAGEPINEPVVAYGPFVMNTKEEIRQAILDYQTGKFDE
>NZ_CP012152.1|WP_035067472.1|735559_736294_+|metallophosphoesterase-family-protein
METKLAIITDIHGNSAALRAVLDDIDRNNPVEHIYCLGDLVAIGHETNKVLELLFSRNDISYVMGNHDEAILNIMKGKEPGSVGEEKEHHQWIASQLDKKFIPALSKIPKKLYAEYNGKKLLFVHYHLNEENQFIPIDQQPTIKKLDELYKTSDVDVVCFGHHHILHHFRSKERLYINPGALGCYHKPLAPYAILNIGAEGISVTFKEVAYDNREFLLAYDKLKVPARDFILRVFYGNQHLQFN

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Crispr_ID: NZ_CP012152_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012152_3

1992597-1995072

Unclear

I-A

Consensus_repeat	Method
CTTTACATCCCACTACGTTCAGATAAAAC	PILER-CR
CTTTACATCCCACTACGTTCAGATAAAAC	CRISPRCasFinder
CTTTACATCCCACTACGTTCAGATAAAAC	CRT

37 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2

The CRISPR arrays of NZ_CP012152_3

>merge|NZ_CP012152|3|1992597-1995072|PILER-CR,CRISPRCasFinder,CRT
CTTTACATCCCACTACGTTCAGATAAAACCGAACCTTCGCACAATTATGCGCGATGACTATAAATTCCTTTACATCCCACTACGTTCAGATAAAACGGAAAATTAAGAATAAATGAGTGCAGAAAGAGCAACTTTACATCCCACTACGTTCAGATAAAACATTTAACACATCTGTGTCATCGTACTCGACAATCTGCTTTACATCCCACTACGTTCAGATCAAACAAAACAATCAAAAACAATGTTGACAAATAAACAACACTCTTTACATCCCACTACGTTCAGATAAAACATAAAGAAACAAGGAGGGAGCAATAATGTCGAGTATCTTTACATCCCACTACGTTCAGATAAAACACTATCATGGGATGGACGTTATCCTTGTTTATTTTTCCTTTACATCCCACTACGTTCAGATAAAACCGAGTATCGAGGTCAGACAATTCTGCAGGTTCAGCCTTTACATCCCACTACGTTCAGATAAAACGACACAAGCGGTTTAAACGACAAACACCGATTTTACTTTACATCCCACTACGTTCAGATAAAACAATACACATCGGACATTCAACCCCTAGCGGCTCAATGCACTTTACATCCCACTACGTTCAGATAAAACACTTTCGTCAAAAATAGTAGAAAAGCCGAAAGAAGAACTTTACATCCCACTACGTTCAGATAAAACTTGAGTTTCGACGCATAGTCCGCAACATAAGATAAGTCGATCTTTACATCCCACTACGTTCAGATAAAACCAATAACGCCATCCCCACAACTAATAGTTCCTATTATCTTTACATCCCACTACGTTCAGATAAAACAAAATCCCATTTGTTCAAGCTTCTTTCTCGCTTTCTTTACATCCCACTACGTTCAGATAAAACTAATTGTCGGTTCTCACACTCGAAACAATGTTCATGCTTTACATCCCACTACGTTCAGATAAAACTGTAGACGGCAGGTATAACTCTACACCATACGAAAGCTTTACATCCCACTACGTTCAGATAAAACCGCCACCTCATAGAACCCGATTGCGTTCCCGAATATCGCCTTTACATCCCACTACGTTCAGATAAAACGAAAAATTCGTGAGACGTTTGGATGCAAGTTGGTACTTCTTTACATCCCACTACGTTCAGATAAAACAATGGATTCCAAATGTGCGAAGATTTAGGCACAATTCTACTTTACATCCCACTACGTTCAGATAAAACGGAGAACATTGGTGCATTGATTGTGCAATTGCTCACTTTACATCCCACTACGTTCAGATAAAACTTAAAGATATTCCTAGCACATTAGCAACTAACTAATGCTTTACATCCCACTACGTTCAGATAAAACATTCGAGCGGAATTATTGAAATTAAACGGTGTTCGAGCAGCTTTACATCCCACTACGTTCAGATAAAACTGAATCGTTTAGCGCATCTTTCACGTCAACGACAACTTTACATCCCACTACGTTCAGATAAAACTGCTGACACCTTGCATTTTTAAATCAACCTGTTTATGCTTTACATCCCACTACGTTCAGATAAAACAATTCAAAAATCCGGGCGGGCTCCGACGATGGTTGTTCTCTTTACATCCCACTACGTTCAGATAAAACTTAGCCAAAATTTATAATTCTAATGTTGATTTTATTACTTTACATCCCACTACGTTCAGATAAAACTAAACGCCATTACTCCTATCCTTCAAGAAGTTGGTCAACTTTACATCCCACTACGTTCAGATAAAACATGGGTTAGCACTTAAAGAAGTCGCTAACCTCAGAATGCTTTACATCCCACTACGTTCAGATAAAACATTGCCAATTCCAAAAGACCAAGAAGGAACGCCAAACACCTTTACATCCCACTACGTTCAGATAAAACTGGAACGAAAGGACAAGCCGTTAATGTCCCTAGTTTCTTTACATCCCACTACGTTCAGATAAAACTTGAGAAAAGGAACGTTACTAATACAAAAGATACACCTTTACATCCCACTACGTTCAGATAAAACTCATTAAAAGCATGATTGCAAAAGCCTACCAAGACACCTTTACATCCCACTACGTTCAGATAAAACTATAAAATCAACCCGGCAACAATTTTGTTTGTGATGTCCTTTACATCCCACTACGTTCAGATAAAACGTGTTACTGAAAGAATGGAACAGCATGCAGGATCAGCTTTACATCCCACTACGTTCAGATAAAACGTTTTCTGTTTTCTCGATTCGGAAAGATGTATTGTTGCACTTTACATCCCACTACGTTCAGATAAAACTGAACAGCTTAAATTCGCAACGAAGCTCTACCTTCTTTACATCCCACTACGTTCAGATAAAACTTGCTCAAATTGAAATGACGATGCTGCGTTTATACGGCTTTACATCCCACTACGTTCAGATAAAACGACTTAATGCGTATTTATATTCATCTACAGGAGTTTTCATCTTTACATCCCACTACGTTCAGATAAAAC

>NZ_CP012152|3|2|1992597-1995072|PILER-CR
CTTTACATCCCACTACGTTCAGATAAAAC	CGAACCTTCGCACAATTATGCGCGATGACTATAAATTC
CTTTACATCCCACTACGTTCAGATAAAAC	GGAAAATTAAGAATAAATGAGTGCAGAAAGAGCAA
CTTTACATCCCACTACGTTCAGATAAAAC	ATTTAACACATCTGTGTCATCGTACTCGACAATCTG
CTTTACATCCCACTACGTTCAGATCAAAC	AAAACAATCAAAAACAATGTTGACAAATAAACAACACT
CTTTACATCCCACTACGTTCAGATAAAAC	ATAAAGAAACAAGGAGGGAGCAATAATGTCGAGTAT
CTTTACATCCCACTACGTTCAGATAAAAC	ACTATCATGGGATGGACGTTATCCTTGTTTATTTTTC
CTTTACATCCCACTACGTTCAGATAAAAC	CGAGTATCGAGGTCAGACAATTCTGCAGGTTCAGC
CTTTACATCCCACTACGTTCAGATAAAAC	GACACAAGCGGTTTAAACGACAAACACCGATTTTA
CTTTACATCCCACTACGTTCAGATAAAAC	AATACACATCGGACATTCAACCCCTAGCGGCTCAATGCA
CTTTACATCCCACTACGTTCAGATAAAAC	ACTTTCGTCAAAAATAGTAGAAAAGCCGAAAGAAGAA
CTTTACATCCCACTACGTTCAGATAAAAC	TTGAGTTTCGACGCATAGTCCGCAACATAAGATAAGTCGAT
CTTTACATCCCACTACGTTCAGATAAAAC	CAATAACGCCATCCCCACAACTAATAGTTCCTATTAT
CTTTACATCCCACTACGTTCAGATAAAAC	AAAATCCCATTTGTTCAAGCTTCTTTCTCGCTTT
CTTTACATCCCACTACGTTCAGATAAAAC	TAATTGTCGGTTCTCACACTCGAAACAATGTTCATG
CTTTACATCCCACTACGTTCAGATAAAAC	TGTAGACGGCAGGTATAACTCTACACCATACGAAAG
CTTTACATCCCACTACGTTCAGATAAAAC	CGCCACCTCATAGAACCCGATTGCGTTCCCGAATATCGC
CTTTACATCCCACTACGTTCAGATAAAAC	GAAAAATTCGTGAGACGTTTGGATGCAAGTTGGTACTT
CTTTACATCCCACTACGTTCAGATAAAAC	AATGGATTCCAAATGTGCGAAGATTTAGGCACAATTCTA
CTTTACATCCCACTACGTTCAGATAAAAC	GGAGAACATTGGTGCATTGATTGTGCAATTGCTCA
CTTTACATCCCACTACGTTCAGATAAAAC	TTAAAGATATTCCTAGCACATTAGCAACTAACTAATG
CTTTACATCCCACTACGTTCAGATAAAAC	ATTCGAGCGGAATTATTGAAATTAAACGGTGTTCGAGCAG
CTTTACATCCCACTACGTTCAGATAAAAC	TGAATCGTTTAGCGCATCTTTCACGTCAACGACAA
CTTTACATCCCACTACGTTCAGATAAAAC	TGCTGACACCTTGCATTTTTAAATCAACCTGTTTATG
CTTTACATCCCACTACGTTCAGATAAAAC	AATTCAAAAATCCGGGCGGGCTCCGACGATGGTTGTTCT
CTTTACATCCCACTACGTTCAGATAAAAC	TTAGCCAAAATTTATAATTCTAATGTTGATTTTATTA
CTTTACATCCCACTACGTTCAGATAAAAC	TAAACGCCATTACTCCTATCCTTCAAGAAGTTGGTCAA
CTTTACATCCCACTACGTTCAGATAAAAC	ATGGGTTAGCACTTAAAGAAGTCGCTAACCTCAGAATG
CTTTACATCCCACTACGTTCAGATAAAAC	ATTGCCAATTCCAAAAGACCAAGAAGGAACGCCAAACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TGGAACGAAAGGACAAGCCGTTAATGTCCCTAGTTT
CTTTACATCCCACTACGTTCAGATAAAAC	TTGAGAAAAGGAACGTTACTAATACAAAAGATACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TCATTAAAAGCATGATTGCAAAAGCCTACCAAGACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TATAAAATCAACCCGGCAACAATTTTGTTTGTGATGTC
CTTTACATCCCACTACGTTCAGATAAAAC	GTGTTACTGAAAGAATGGAACAGCATGCAGGATCAG
CTTTACATCCCACTACGTTCAGATAAAAC	GTTTTCTGTTTTCTCGATTCGGAAAGATGTATTGTTGCA
CTTTACATCCCACTACGTTCAGATAAAAC	TGAACAGCTTAAATTCGCAACGAAGCTCTACCTT
CTTTACATCCCACTACGTTCAGATAAAAC	TTGCTCAAATTGAAATGACGATGCTGCGTTTATACGG
CTTTACATCCCACTACGTTCAGATAAAAC	GACTTAATGCGTATTTATATTCATCTACAGGAGTTTTCAT
CTTTACATCCCACTACGTTCAGATAAAAC

>NZ_CP012152|3|3|1992597-1995072|CRISPRCasFinder
CTTTACATCCCACTACGTTCAGATAAAAC	CGAACCTTCGCACAATTATGCGCGATGACTATAAATTC
CTTTACATCCCACTACGTTCAGATAAAAC	GGAAAATTAAGAATAAATGAGTGCAGAAAGAGCAA
CTTTACATCCCACTACGTTCAGATAAAAC	ATTTAACACATCTGTGTCATCGTACTCGACAATCTG
CTTTACATCCCACTACGTTCAGATCAAAC	AAAACAATCAAAAACAATGTTGACAAATAAACAACACT
CTTTACATCCCACTACGTTCAGATAAAAC	ATAAAGAAACAAGGAGGGAGCAATAATGTCGAGTAT
CTTTACATCCCACTACGTTCAGATAAAAC	ACTATCATGGGATGGACGTTATCCTTGTTTATTTTTC
CTTTACATCCCACTACGTTCAGATAAAAC	CGAGTATCGAGGTCAGACAATTCTGCAGGTTCAGC
CTTTACATCCCACTACGTTCAGATAAAAC	GACACAAGCGGTTTAAACGACAAACACCGATTTTA
CTTTACATCCCACTACGTTCAGATAAAAC	AATACACATCGGACATTCAACCCCTAGCGGCTCAATGCA
CTTTACATCCCACTACGTTCAGATAAAAC	ACTTTCGTCAAAAATAGTAGAAAAGCCGAAAGAAGAA
CTTTACATCCCACTACGTTCAGATAAAAC	TTGAGTTTCGACGCATAGTCCGCAACATAAGATAAGTCGAT
CTTTACATCCCACTACGTTCAGATAAAAC	CAATAACGCCATCCCCACAACTAATAGTTCCTATTAT
CTTTACATCCCACTACGTTCAGATAAAAC	AAAATCCCATTTGTTCAAGCTTCTTTCTCGCTTT
CTTTACATCCCACTACGTTCAGATAAAAC	TAATTGTCGGTTCTCACACTCGAAACAATGTTCATG
CTTTACATCCCACTACGTTCAGATAAAAC	TGTAGACGGCAGGTATAACTCTACACCATACGAAAG
CTTTACATCCCACTACGTTCAGATAAAAC	CGCCACCTCATAGAACCCGATTGCGTTCCCGAATATCGC
CTTTACATCCCACTACGTTCAGATAAAAC	GAAAAATTCGTGAGACGTTTGGATGCAAGTTGGTACTT
CTTTACATCCCACTACGTTCAGATAAAAC	AATGGATTCCAAATGTGCGAAGATTTAGGCACAATTCTA
CTTTACATCCCACTACGTTCAGATAAAAC	GGAGAACATTGGTGCATTGATTGTGCAATTGCTCA
CTTTACATCCCACTACGTTCAGATAAAAC	TTAAAGATATTCCTAGCACATTAGCAACTAACTAATG
CTTTACATCCCACTACGTTCAGATAAAAC	ATTCGAGCGGAATTATTGAAATTAAACGGTGTTCGAGCAG
CTTTACATCCCACTACGTTCAGATAAAAC	TGAATCGTTTAGCGCATCTTTCACGTCAACGACAA
CTTTACATCCCACTACGTTCAGATAAAAC	TGCTGACACCTTGCATTTTTAAATCAACCTGTTTATG
CTTTACATCCCACTACGTTCAGATAAAAC	AATTCAAAAATCCGGGCGGGCTCCGACGATGGTTGTTCT
CTTTACATCCCACTACGTTCAGATAAAAC	TTAGCCAAAATTTATAATTCTAATGTTGATTTTATTA
CTTTACATCCCACTACGTTCAGATAAAAC	TAAACGCCATTACTCCTATCCTTCAAGAAGTTGGTCAA
CTTTACATCCCACTACGTTCAGATAAAAC	ATGGGTTAGCACTTAAAGAAGTCGCTAACCTCAGAATG
CTTTACATCCCACTACGTTCAGATAAAAC	ATTGCCAATTCCAAAAGACCAAGAAGGAACGCCAAACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TGGAACGAAAGGACAAGCCGTTAATGTCCCTAGTTT
CTTTACATCCCACTACGTTCAGATAAAAC	TTGAGAAAAGGAACGTTACTAATACAAAAGATACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TCATTAAAAGCATGATTGCAAAAGCCTACCAAGACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TATAAAATCAACCCGGCAACAATTTTGTTTGTGATGTC
CTTTACATCCCACTACGTTCAGATAAAAC	GTGTTACTGAAAGAATGGAACAGCATGCAGGATCAG
CTTTACATCCCACTACGTTCAGATAAAAC	GTTTTCTGTTTTCTCGATTCGGAAAGATGTATTGTTGCA
CTTTACATCCCACTACGTTCAGATAAAAC	TGAACAGCTTAAATTCGCAACGAAGCTCTACCTT
CTTTACATCCCACTACGTTCAGATAAAAC	TTGCTCAAATTGAAATGACGATGCTGCGTTTATACGG
CTTTACATCCCACTACGTTCAGATAAAAC	GACTTAATGCGTATTTATATTCATCTACAGGAGTTTTCAT
CTTTACATCCCACTACGTTCAGATAAAAC

>NZ_CP012152|3|2|1992597-1995072|CRT
CTTTACATCCCACTACGTTCAGATAAAAC	CGAACCTTCGCACAATTATGCGCGATGACTATAAATTC
CTTTACATCCCACTACGTTCAGATAAAAC	GGAAAATTAAGAATAAATGAGTGCAGAAAGAGCAA
CTTTACATCCCACTACGTTCAGATAAAAC	ATTTAACACATCTGTGTCATCGTACTCGACAATCTG
CTTTACATCCCACTACGTTCAGATCAAAC	AAAACAATCAAAAACAATGTTGACAAATAAACAACACT
CTTTACATCCCACTACGTTCAGATAAAAC	ATAAAGAAACAAGGAGGGAGCAATAATGTCGAGTAT
CTTTACATCCCACTACGTTCAGATAAAAC	ACTATCATGGGATGGACGTTATCCTTGTTTATTTTTC
CTTTACATCCCACTACGTTCAGATAAAAC	CGAGTATCGAGGTCAGACAATTCTGCAGGTTCAGC
CTTTACATCCCACTACGTTCAGATAAAAC	GACACAAGCGGTTTAAACGACAAACACCGATTTTA
CTTTACATCCCACTACGTTCAGATAAAAC	AATACACATCGGACATTCAACCCCTAGCGGCTCAATGCA
CTTTACATCCCACTACGTTCAGATAAAAC	ACTTTCGTCAAAAATAGTAGAAAAGCCGAAAGAAGAA
CTTTACATCCCACTACGTTCAGATAAAAC	TTGAGTTTCGACGCATAGTCCGCAACATAAGATAAGTCGAT
CTTTACATCCCACTACGTTCAGATAAAAC	CAATAACGCCATCCCCACAACTAATAGTTCCTATTAT
CTTTACATCCCACTACGTTCAGATAAAAC	AAAATCCCATTTGTTCAAGCTTCTTTCTCGCTTT
CTTTACATCCCACTACGTTCAGATAAAAC	TAATTGTCGGTTCTCACACTCGAAACAATGTTCATG
CTTTACATCCCACTACGTTCAGATAAAAC	TGTAGACGGCAGGTATAACTCTACACCATACGAAAG
CTTTACATCCCACTACGTTCAGATAAAAC	CGCCACCTCATAGAACCCGATTGCGTTCCCGAATATCGC
CTTTACATCCCACTACGTTCAGATAAAAC	GAAAAATTCGTGAGACGTTTGGATGCAAGTTGGTACTT
CTTTACATCCCACTACGTTCAGATAAAAC	AATGGATTCCAAATGTGCGAAGATTTAGGCACAATTCTA
CTTTACATCCCACTACGTTCAGATAAAAC	GGAGAACATTGGTGCATTGATTGTGCAATTGCTCA
CTTTACATCCCACTACGTTCAGATAAAAC	TTAAAGATATTCCTAGCACATTAGCAACTAACTAATG
CTTTACATCCCACTACGTTCAGATAAAAC	ATTCGAGCGGAATTATTGAAATTAAACGGTGTTCGAGCAG
CTTTACATCCCACTACGTTCAGATAAAAC	TGAATCGTTTAGCGCATCTTTCACGTCAACGACAA
CTTTACATCCCACTACGTTCAGATAAAAC	TGCTGACACCTTGCATTTTTAAATCAACCTGTTTATG
CTTTACATCCCACTACGTTCAGATAAAAC	AATTCAAAAATCCGGGCGGGCTCCGACGATGGTTGTTCT
CTTTACATCCCACTACGTTCAGATAAAAC	TTAGCCAAAATTTATAATTCTAATGTTGATTTTATTA
CTTTACATCCCACTACGTTCAGATAAAAC	TAAACGCCATTACTCCTATCCTTCAAGAAGTTGGTCAA
CTTTACATCCCACTACGTTCAGATAAAAC	ATGGGTTAGCACTTAAAGAAGTCGCTAACCTCAGAATG
CTTTACATCCCACTACGTTCAGATAAAAC	ATTGCCAATTCCAAAAGACCAAGAAGGAACGCCAAACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TGGAACGAAAGGACAAGCCGTTAATGTCCCTAGTTT
CTTTACATCCCACTACGTTCAGATAAAAC	TTGAGAAAAGGAACGTTACTAATACAAAAGATACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TCATTAAAAGCATGATTGCAAAAGCCTACCAAGACAC
CTTTACATCCCACTACGTTCAGATAAAAC	TATAAAATCAACCCGGCAACAATTTTGTTTGTGATGTC
CTTTACATCCCACTACGTTCAGATAAAAC	GTGTTACTGAAAGAATGGAACAGCATGCAGGATCAG
CTTTACATCCCACTACGTTCAGATAAAAC	GTTTTCTGTTTTCTCGATTCGGAAAGATGTATTGTTGCA
CTTTACATCCCACTACGTTCAGATAAAAC	TGAACAGCTTAAATTCGCAACGAAGCTCTACCTT
CTTTACATCCCACTACGTTCAGATAAAAC	TTGCTCAAATTGAAATGACGATGCTGCGTTTATACGG
CTTTACATCCCACTACGTTCAGATAAAAC	GACTTAATGCGTATTTATATTCATCTACAGGAGTTTTCAT
CTTTACATCCCACTACGTTCAGATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012152.1\|WP_035067724.1\|2003196_2003952_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NZ_CP012152.1\|WP_026011532.1\|1984230_1985334_-\|ribosome-biogenesis-GTPase-YqeH	unknown	unknown	gnl\|CDD\|237511
NZ_CP012152.1\|WP_035066615.1\|1991666_1992452_-\|DUF4405-domain-containing-protein	unknown	unknown	gnl\|CDD\|379580
NZ_CP012152.1\|WP_035066613.1\|1996510_1997008_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP012152.1\|WP_026011531.1\|1987862_1988663_+\|flagellar-motor-stator-protein-MotA	unknown	unknown	gnl\|CDD\|181238
NZ_CP012152.1\|WP_035066619.1\|1989428_1990742_-\|Ktr-system-potassium-transporter-B	unknown	unknown	gnl\|CDD\|273349
NZ_CP012152.1\|WP_049720849.1\|2003948_2005151_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NZ_CP012152.1\|WP_035066617.1\|1990920_1991634_+\|RNA-polymerase-sporulation-sigma-factor-SigK	unknown	unknown	gnl\|CDD\|180266
NZ_CP012152.1\|WP_035066622.1\|1988646_1989402_+\|flagellar-motor-protein-MotB	unknown	unknown	gnl\|CDD\|236080
NZ_CP012152.1\|WP_009361655.1\|1995525_1996509_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NZ_CP012152.1\|WP_035066607.1\|1999213_1999921_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
NZ_CP012152.1\|WP_009374076.1\|1986130_1986271_+\|sporulation-histidine-kinase-inhibitor-Sda	unknown	unknown	gnl\|CDD\|370219
NZ_CP012152.1\|WP_035066610.1\|1997024_1999202_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NZ_CP012152.1\|WP_019416874.1\|1986282_1987080_-\|phosphatidylserine-decarboxylase	unknown	unknown	gnl\|CDD\|179544
NZ_CP012152.1\|WP_009361654.1\|1995259_1995523_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP012152.1\|WP_009374074.1\|1985339_1985852_-\|YqeG-family-HAD-IIIA-type-phosphatase	unknown	unknown	gnl\|CDD\|225090
NZ_CP012152.1\|WP_009374081.1\|1987204_1987744_+\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|224104
NZ_CP012152.1\|WP_009361659.1\|1999923_2000811_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NZ_CP012152.1\|WP_035066605.1\|2000807_2002586_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|162595
NZ_CP012152.1\|WP_035067204.1\|2005669_2006293_+\|YHYH-domain-containing-protein	unknown	unknown	gnl\|CDD\|214615

Protein	Function_ID	Function_description	E-value
NZ_CP012152.1\|WP_035067724.1\|2003196_2003952_-\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	4.05462e-89
NZ_CP012152.1\|WP_026011532.1\|1984230_1985334_-\|ribosome-biogenesis-GTPase-YqeH	gnl\|CDD\|237511	PRK13796, PRK13796, GTPase YqeH; Provisional.	0
NZ_CP012152.1\|WP_035066615.1\|1991666_1992452_-\|DUF4405-domain-containing-protein	gnl\|CDD\|379580	pfam14358, DUF4405, Domain of unknown function (DUF4405). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and archaea, and is approximately 50 amino acids in length. There are two conserved histidines that may be functionally important. This family is N-terminally truncated compared to other members of the clan.	2.20048e-08
NZ_CP012152.1\|WP_035066613.1\|1996510_1997008_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	7.2712e-60
NZ_CP012152.1\|WP_026011531.1\|1987862_1988663_+\|flagellar-motor-stator-protein-MotA	gnl\|CDD\|181238	PRK08124, PRK08124, flagellar motor protein MotA; Validated.	6.17091e-172
NZ_CP012152.1\|WP_035066619.1\|1989428_1990742_-\|Ktr-system-potassium-transporter-B	gnl\|CDD\|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	2.26691e-100
NZ_CP012152.1\|WP_049720849.1\|2003948_2005151_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.46289e-56
NZ_CP012152.1\|WP_035066617.1\|1990920_1991634_+\|RNA-polymerase-sporulation-sigma-factor-SigK	gnl\|CDD\|180266	PRK05803, PRK05803, RNA polymerase sporulation sigma factor SigK.	7.24373e-146
NZ_CP012152.1\|WP_035066622.1\|1988646_1989402_+\|flagellar-motor-protein-MotB	gnl\|CDD\|236080	PRK07734, motB, flagellar motor protein MotB; Reviewed.	9.23281e-156
NZ_CP012152.1\|WP_009361655.1\|1995525_1996509_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.87917e-166
NZ_CP012152.1\|WP_035066607.1\|1999213_1999921_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	7.81884e-35
NZ_CP012152.1\|WP_009374076.1\|1986130_1986271_+\|sporulation-histidine-kinase-inhibitor-Sda	gnl\|CDD\|370219	pfam08970, Sda, Sporulation inhibitor A. Members of this protein family contain two antiparallel alpha helices that are linked by a highly structured inter-helix loop to form a helical hairpin; the structure is stabilized by numerous hydrophobic and electrostatic interactions. These sporulation inhibitors are antikinases that bind to the histidine kinase KinA phosphotransfer domain and act as a molecular barricade that inhibit productive interaction between the ATP binding site and the phosphorylatable KinA His residue. This results in the inhibition of sporulation (by preventing phosphorylation of spo0A).	3.29125e-15
NZ_CP012152.1\|WP_035066610.1\|1997024_1999202_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	4.62751e-68
NZ_CP012152.1\|WP_019416874.1\|1986282_1987080_-\|phosphatidylserine-decarboxylase	gnl\|CDD\|179544	PRK03140, PRK03140, phosphatidylserine decarboxylase; Provisional.	8.1023e-169
NZ_CP012152.1\|WP_009361654.1\|1995259_1995523_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.44851e-28
NZ_CP012152.1\|WP_009374074.1\|1985339_1985852_-\|YqeG-family-HAD-IIIA-type-phosphatase	gnl\|CDD\|225090	COG2179, COG2179, Predicted hydrolase of the HAD superfamily [General function prediction only].	1.32914e-80
NZ_CP012152.1\|WP_009374081.1\|1987204_1987744_+\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	gnl\|CDD\|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	4.20578e-43
NZ_CP012152.1\|WP_009361659.1\|1999923_2000811_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	3.73079e-59
NZ_CP012152.1\|WP_035066605.1\|2000807_2002586_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|162595	TIGR01908, Uncharacterized_protein_aq_372, CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This (revised) model describes a conserved region from an otherwise highly divergent protein found in the Tneap subtype of CRISPR/Cas regions. This Cys-rich region features two motifs of CXXC.	2.01814e-07
NZ_CP012152.1\|WP_035067204.1\|2005669_2006293_+\|YHYH-domain-containing-protein	gnl\|CDD\|214615	smart00318, SNc, Staphylococcal nuclease homologues.	1.50258e-38

>NZ_CP012152.1|WP_035066615.1|1991666_1992452_-|DUF4405-domain-containing-protein
MLKKNIVKIILDVSMAIAFVLLMNPRVFNGLPFHEIAGTVIGVAILVHIGLNYRWVINTTKKIFSSELPKKTRISFALNILLLVSMAAVIVSGILISRVLFSNVALEGNHFVREIHDLFANTTLALVGLHLGLHWQWIMGVSKKVFKAKDGTWRKGAFISSVLIFALLAGGMYWSSQYVKPSEGEFKPKFAEQNAPSFAGKTVGTLPTPPDGAFRHEKFLKEHGTNNPLLVLLHYFTIWTVMIVPTYYIEKRMRNKRKLSV
>NZ_CP012152.1|WP_035066617.1|1990920_1991634_+|RNA-polymerase-sporulation-sigma-factor-SigK
MGAIFSALALFIKELVFFVSYVKNNAFPQPLDAKEEAMYLKQMAKGDEYARNKLIEHNLRLVAHIVKKFENTGEDPEDLISIGTIGLIKAIESYSTGKGTKLATYAARCIENEILMHLRSLKKTRKDVSLHDPIGQDRDGNEISLLDVLKSEDEDIIDMIEKNNELENIAQHLHVLDDRERQVIVSRFGLNMQPERTQREIAKELGISRSYVSRIEKRALMKLYHECYKHDKGKKGS
>NZ_CP012152.1|WP_035066619.1|1989428_1990742_-|Ktr-system-potassium-transporter-B
MKPLKLTPPQLLAGMFLFLVVVGGGLLKLPIATEKEISWLDAFFLSTSAATVTGLAPIDPGSTFTVFGEIVLMVLIQVGGLGVMTFAVLVVIVLGKKIGMKQRMLMQEALNQPSLGGVIRLARNLLLFSLFMEVVGAVLLAIDWVPKMGWAKGVYYSVFHTIASFNNAGFALWPDNLSRFVDDPIVNVTVSLLIIIGGLGFTVVFDVLYQRRWRKLSIHTKLMLVMTLVVNIVAIIAFFLFEHNNPKTLGSLSLREQLWASYFQGITPRTAGFNTIDIGSIEQPTAMLMIFLMFIGAGSTSTGGGIKLTTFAVIIFAVMSFLKGKEETVVWMRTIRHTIILRALAIASMSMLFIFVMTMILTLTEDASLLALLFEVVSAFGTVGLSMNMTSHLSTIGKMLIIFVMLFGKLGPLTLVYSIAKPKKTNIRYPNGDILTG
>NZ_CP012152.1|WP_035066622.1|1988646_1989402_+|flagellar-motor-protein-MotB
MAKKHKKHHHEDHIDESWLIPYADLLTLLLALFIVLFASSQIDSEKFQQIAKSFNSILTGGTGALQYLSPIDREKIDSVIKDSPSQKPYVKISKKEYEELKKIQSKFNEYVKTNQLSGELSVAMTEEGLLVTIANDVLFDSGSADIKPQYRDVAKKISNLLVMNPPRNIVISGHTDNVPINNAKFASNWELSVMRAVNFMKLLLENTRLNPQLFSAKGYGEFKPIASNATPEGRAKNRRVEILIMPQEPAQ
>NZ_CP012152.1|WP_026011531.1|1987862_1988663_+|flagellar-motor-stator-protein-MotA
MDRTSLIGLILGIIAVGVGMMFKGVSPAVLINPAAILIILLGTAAAVTIAFPTKEIAKVPKLFGVIFKEPKTPKIEELIPLFVEWANIARREGLLALEAKVAEIDDPFLRNGLSLAIDGQSQEFIRDVMTEEIEAMQERHLANATIFTQAGTYAPTLGVLGAVVGLIAALQDMSDIDRLGHAISAAFVATLMGIFTGYVLWHPFANKLKRKSKEEVKVRQVMIEGVLSIIEGQAPRAIEQKLASYLPMSERQKLLGQGAQNNGEKA
>NZ_CP012152.1|WP_009374081.1|1987204_1987744_+|CDP-diacylglycerol--serine-O-phosphatidyltransferase
MFLSDYIDHTIKKLKAHTANVLTLTNLSLGGFAILFAVKGQLNVSVLFIFLAALADRFDGTVARKMNIESDLGKQLDSMSDIISFGVAPALLLYQGLLHEFGAPGSFFTIFYIGCGAFRLARFNITESNGYFTGLPITAAGCLLTLSYLTIHYFPPYVFIFIIFTLSLLMVGSFRLKKM
>NZ_CP012152.1|WP_019416874.1|1986282_1987080_-|phosphatidylserine-decarboxylase
MVKWLYRLFIELTNHPLTSKWLASFTRSKWSRWVIPSYAKVYKVDEEEMEKKLHEYETLQQLFVRSLKKGLRPIDEHPDSVVSPVDAVIEDVGIITDKKEIIVKGKTYSIREMLGDDRIAEKYLHGTFIILYLSPSHYHRIHSPICGEVVKQWELGGKSYPVNRLGLKYGKDPLSKNYRRITELCTNGMHTAIVKVGAMFVNSIELTHEHNYVNKGEEIGYFSFGSTVVLLFEKGAFTLDEQIIPPLEVKMGQRLGFFAQKKKSQ
>NZ_CP012152.1|WP_009374076.1|1986130_1986271_+|sporulation-histidine-kinase-inhibitor-Sda
MKCLPDDLLIESYYKAKELQLSKEFIQLIEREIFRRRLDHKIKQSS
>NZ_CP012152.1|WP_009374074.1|1985339_1985852_-|YqeG-family-HAD-IIIA-type-phosphatase
MLKYFLPNEHAKSIFEITPEHLKQKGIKGIITDLDNTLIEWDRPLATPDVVRWFEQMKQSGIQVTVVSNNNKKRVEAFAKPLGIPFIFEARKPLTRAFQQALRDMKLKKEEVVVIGDQLLTDVFGGNRLGLHTILVVPVAQTDGFFTRINRNIERKILNMMRKKGMIHWE
>NZ_CP012152.1|WP_026011532.1|1984230_1985334_-|ribosome-biogenesis-GTPase-YqeH
MSEQMICIGCGVTIQTEDETKIGYAPPSALEKDPVICQRCFRLKHYNEVQDVSLTDDDFLNILHGIGQADGLVVKIVDIFDFNGSWLPGLHRFVGKKDVLLVGNKVDLLPKSVKHEKVTRWMKQSARELGLQPRDVFLVSANKGYGMKEVMAAIDEYRNGKDVYVVGCTNVGKSTFINRIIKEATGKGNVITTSYFPGTTLDMIEIPLDDGSALYDTPGIINHHQMAHFVDKKDLKVITPKKEIKPKVYQLNEQQTLFFGGLARLDYVSGGRRPFVCYMSNELFIHRTKREHADELYEKHLGELLQPPRKSYCEQLPPLVAHHFTLKEPKTDIVFSGLGWVTCHEPGAHVVAYAPKGVGVMLRRSLI
>NZ_CP012152.1|WP_009361654.1|1995259_1995523_-|CRISPR-associated-endonuclease-Cas2
MFVIITYDVGEKRVNKVCKKLREYLTWTQNSVFEGEISKSLLMKCLNEIDQIIDEDEDSIYIYEVANPKNIKKQVFGQEKNFDELFL
>NZ_CP012152.1|WP_009361655.1|1995525_1996509_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MLRDHYIFSNGRLKRKDNTLYFFDEQENKKSLPVHQTDNLYIFGEVDLNSSLLNLLSQHDVHLHVFNYYGFYAGTFCPRNKKVSGFTVVQQSVHYLEHEKRLYMARSFLQSAVHHMLRNIRRYKEKTEQYVKNIEEEAKKMDSATTIQELMGIEGRIRQHYYQSFNAILKQDFIFEKRTKQPPQDPLNALISFGNSLCYTTVLSEIYKTQLDPTISFLHEPSTKRFSLCLDLAEIFKPLLVDVVIISCINNRIITQKHFDFLDGMVLLNEEGKKRFIKEWDEKLSTTVQHRKLKRKVSYRYFIRLECYKLIKHFIGDEPYKPLKAWW
>NZ_CP012152.1|WP_035066613.1|1996510_1997008_-|CRISPR-associated-protein-Cas4
MVSGVQMQYYKVCKRKLWLFSKGIAMENEHERVIEGKILHERAYPRLEDREILVDDTFKLDALDKEYVREIKISSKMPEADRFQMLYYLYELKKRGITKKGLISYTKERKTEEVELTEKDESAIEKAIKEIYVILQSPSPPRLKKLPYCTKCAYYEFCFALEGDD
>NZ_CP012152.1|WP_035066610.1|1997024_1999202_-|CRISPR-associated-helicase/endonuclease-Cas3
MAFYAKSEGKETIREHTDRLLHNLNLLKDAYGHKFMLMDEQMWKLLEIAVQYHDVGKANTVFQNKIRQAIHESMLETDVETNVPHNYLSAGCIPLKQLDLTKEEERLLIHAVGYHHERDQLPEKEMIRHVLENDIKQQLPQLSEHMGLQMTEKFSYRFVDRLLKRYTYHDGEEFWKYVMIKGLLHRLDHAASAHMDVERDVEKSVYINVNEYMQKQGFHKNDLQQFTEQHHDKNVIAIAQTGMGKTEAALLWIREDKAFFTLPLRVSINAIYDRIKEKMGYDAVGLLHSTSVHYLVDKEENWEELKQQSEHYAKKLLLTTIDQILKFPFYYKGFEKELAAMANAKIVIDEIQAYEPRIAAMLIKALEMIHHVGGKFMIMTATLPTLYLEELKQRNVIHDDEFVTGEFIDTDVHRHRICLRSECIEETIGEMLELGETSQVLVIVNTVRKAMRLYDKFLDCDTQVPIYLLHSQFTQEDRQLLEKRIKQFNEKNERGIWITTQLVEASIDIDFDYLFTEMSTLDSLFQRFGRCYRKRALDHDHCNIHIFTENISGIPRVYNEHLVNESIRLLEQYDYQIVDERAKVEMVKQLYDRKQLKGTSFLKEFEDALYMFDNLDPYGMDKREAQQKLRDIQNIQIITRQMYDQIEHLFEQYKKEKEWKERLKLRMEIEKKTVSVQRYVAEKYVSERLPKPFDHIYIADVQYDFNREQLKGKGILLDKPSSNQY
>NZ_CP012152.1|WP_035066607.1|1999213_1999921_-|type-I-B-CRISPR-associated-protein-Cas5
MKALRLKLFQETACYKKPFASKVAETYPLPPYSTVKGMIHALLDANQFIPMRLSVQGTYEAKLLDYQRYYFFKRRELSSFPLVLDGLARMEFSYDKNEITTMPMYTHLLHNVHLLIHVEAEEHILTQIIHAIEHSTTHYSLGRWEDLVRIDEYKLVEVRELEEDETLTLQRDAYIPRHLLDRETKSIPYQLNWKYEIVNGIRQWEKIHVGYVQKGVEAPEGVWIDEDGELVFYHL
>NZ_CP012152.1|WP_009361659.1|1999923_2000811_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKKALTMTVIFQANSLNYGEGIANISELKKFHRGDGEVYTYASRQSIRYDIVRLGNELFGWNLDTVDKASGVVQFKKDVTINDSVEMDLFGYLKTDKNSQKRPAVVRLSHAISLEPYKSDLEFLNNMGLASRIGQDANLANIEQHHSFYTYTITIDLNRVGVDGEIELPSEEKANRVLQLLEVLKVLNRNIRGRQENLSPLFVIGGMYNVANPFFLGRVQLSVTGNGWAIQTKPIKETMEQTFAGEAIGKDTRIGILSGVFANEGELYDLFNEQVMPVEPFFQYVSKQIKAYYGV
>NZ_CP012152.1|WP_035066605.1|2000807_2002586_-|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MKVELHMGGWMINMGLVGLYRVFEYGRKHEIISEEHKHSVTVKPWGIELDTEVLPQLPRAYFLYLLEEYSVARRECERLDAYIEQVKNEEQFKNHLTAIKKVISDTGTKIIKYFTHETLESILKQIKEIKKYEQVHQLEEHIRTLKQVYSEPKINEKLTFNYFKHAILKPLFFGQVSFLNVSKNNLDFEGHVEEFYNSYIFPVVNDLYLESVINDSHSMEEISSLLEKQSEYQLFRQLKRAWKKKTLEEVREYVKTEINKCLLFNERLAFYNFEEMVFSPIGVAKDKAFNFSWYFNGEQPRPLSSLAKLVLLFAPIGSTIYYKNEGINEQTERRLYAGFVQTDATFAEVLQKNNHFRELKKKREPFNKIVSQLVQSVKKESEYTVDHLFFLEFFSDYDSKKTHLHYYHLPMYLAHYFKQHADRLDYIKPYDYREQFVQSVLRGADPIHVIYHYLRDCIKNERSTNGPYIAVRERNRILQFKKGVRDMATTDKRVTALFMQGREIRDAIIRSSGSEKKVTSIAYRLLNAAKAGNRKSFMDTLLRIYMSTDRPMSPIFLNALHERDLDFATVANAFIAGLLANQYKEEQEEVQA
>NZ_CP012152.1|WP_035067724.1|2003196_2003952_-|ATP-binding-protein
MKEQIHEYCHRLHLPVMAERWSAMTEYAATHNIPYSEFLFRLLEAEIIEKQERSIQTLIKLSKLPYRKTIDTFDFNALPSVDERRIRELLTLSFIDRKENILFLGPPGIGKTHLAISIGMEAIARGYKTYFITAHDLVTQLRKADQEGKLEKKLRMFVKPTILIIDEMGYLKLDPNSAHYLFQVIARRYEHAPIILTSNKSFGEWGEIVGDSVLATAMLDRLLHHSIIFNLKGESYRLREKRLQEEKQKDQ
>NZ_CP012152.1|WP_049720849.1|2003948_2005151_-|IS21-family-transposase
MITRGEFFMIKEMYERGMSISDIARELGIDRKTVRKYIHSPNPPSKSKRKQRKSKLDPFKPYLQKRMLEDGVFNSEKLFFEIRQQGYMGGKTILKDYMKPFRETAKKKYTVRYETLPGEQMQVDWKEVGEVVIEGKKVKLSLFVATLGYSRMKYAVFTTSQDQEHLMECLIQSFKYFGGVPKKVLFDNMKTVTDGREQGVVKWNQRFSEFASYYGFIPKVCRPYRAQTKGKVERAIQYIMDHFYVGTAFESIEELNFLLHRWLDQVANRKPNATTGIPPQERWAEEQLKPLPLNDYDTSYLSYRKVHWDGSFSYKGEQWLLSAEYAGKEILVKERLNGDIRLYYRGEEISYLNQQKKVISFAEKIKKKQTETAVTISPVSVEVDTRPLSVYDTFLRGESS
>NZ_CP012152.1|WP_035067204.1|2005669_2006293_+|YHYH-domain-containing-protein
MLRVLLSLVTAFTIFFTSSAYAHPGKTDANGGHTCRTNCEKWGLKYGEYHYHDKNGNIIRQTNKTIHPPAIRVNSKHVVKVIRVVDGDTIDVRFSNGATSRVRFIGVNTPETVHPQKPVEKYGKEASNYTKKRLTNQTVTLEFDVGVKDKYGRFLAYVWVGKELYNETLVKDGYARVMTIQPNVKYQQRFITAERKARQQKKGLWKL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP012152_3	3.15\|1993546\|36\|NZ_CP012152\|PILER-CR,CRISPRCasFinder,CRT	1993546-1993581	36	NZ_CP012152.1	1410902-1410937	0	1.0

1. spacer 3.15|1993546|36|NZ_CP012152|PILER-CR,CRISPRCasFinder,CRT matches to position: 1410902-1410937, mismatch: 0, identity: 1.0

tgtagacggcaggtataactctacaccatacgaaag	CRISPR spacer
tgtagacggcaggtataactctacaccatacgaaag	Protospacer
************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012152_2	2.3\|724177\|37\|NZ_CP012152\|PILER-CR,CRT	724177-724213	37	AB823818	Phage phi OH2 DNA, complete genome	20793-20829	1	0.973
NZ_CP012152_2	2.3\|724177\|37\|NZ_CP012152\|PILER-CR,CRT	724177-724213	37	NC_009552	Geobacillus virus E2, complete genome	40492-40528	1	0.973
NZ_CP012152_3	3.30\|1994544\|36\|NZ_CP012152\|PILER-CR,CRISPRCasFinder,CRT	1994544-1994579	36	NC_019544	Deep-sea thermophilic phage D6E, complete genome	173-208	1	0.972
NZ_CP012152_2	2.6\|724172\|42\|NZ_CP012152\|CRISPRCasFinder	724172-724213	42	AB823818	Phage phi OH2 DNA, complete genome	20788-20829	5	0.881
NZ_CP012152_2	2.8\|724244\|36\|NZ_CP012152\|CRT	724244-724279	36	MN694140	Marine virus AFVG_250M934, complete genome	31357-31392	9	0.75

1. spacer 2.3|724177|37|NZ_CP012152|PILER-CR,CRT matches to AB823818 (Phage phi OH2 DNA, complete genome) position: , mismatch: 1, identity: 0.973

tacatgcttttcacctcaaatgaaaaacgccacccca	CRISPR spacer
tacatgcttttcacctcaaatgaaaaacgccacccaa	Protospacer
*********************************** *

2. spacer 2.3|724177|37|NZ_CP012152|PILER-CR,CRT matches to NC_009552 (Geobacillus virus E2, complete genome) position: , mismatch: 1, identity: 0.973

tacatgcttttcacctcaaatgaaaaacgccacccca-	CRISPR spacer
tacatgcttttcacctcaaat-aaaaacgccaccccat	Protospacer
********************* ***************

3. spacer 3.30|1994544|36|NZ_CP012152|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 1, identity: 0.972

ttgagaaaaggaacgttactaatacaaaagatacac	CRISPR spacer
ttgagaaaaggaacgttaccaatacaaaagatacac	Protospacer
*******************.****************

4. spacer 2.6|724172|42|NZ_CP012152|CRISPRCasFinder matches to AB823818 (Phage phi OH2 DNA, complete genome) position: , mismatch: 5, identity: 0.881

gaaactacatgcttttcacctcaaatgaaaaacgccacccca	CRISPR spacer
gtttatacatgcttttcacctcaaatgaaaaacgccacccaa	Protospacer
*    *********************************** *

5. spacer 2.8|724244|36|NZ_CP012152|CRT matches to MN694140 (Marine virus AFVG_250M934, complete genome) position: , mismatch: 9, identity: 0.75

atttacattttccgcattttcgtttttattttcttt	CRISPR spacer
gtttacattttccgcactttcgttcttctcatatcc	Protospacer
.***************.*******.** *. * *..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

226626 : 236357

Synechococcus_phage(37.5%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009360741.1\|226626_227922_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.2e-18	34.4
WP_009360740.1\|227988_228711_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HI61	Synechococcus_phage	1.1e-46	44.0
WP_009360739.1\|228698_228953_+	phosphoribosylformylglycinamidine synthase subunit PurS	M4QPE7	Synechococcus_phage	4.2e-06	33.3
WP_009360738.1\|228949_229636_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_019418101.1\|229619_231842_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.1e-161	40.4
WP_035063804.1\|231817_233245_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.3e-48	33.1
WP_009360735.1\|233207_234245_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	9.4e-68	43.9
WP_009360734.1\|234241_234844_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.6e-25	38.3
WP_165569749.1\|234818_236357_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.5e-77	50.7

DBSCAN-SWA_2

390501 : 462101

Vibrio_phage(23.08%)

transposase,capsid,holin,terminase,head,plate,tail,tRNA,portal,protease,integrase

attL 408475:408492|attR 460916:460933

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049720849.1\|390501_391704_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.0e-49	37.6
WP_049720851.1\|392187_392400_+	hypothetical protein	NA	NA	NA	NA
WP_049720840.1\|392450_393899_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_049720852.1\|394129_394672_+	phosphotransferase	NA	NA	NA	NA
WP_035067858.1\|394942_395368_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_035067856.1\|395355_395691_+	DUF3147 family protein	NA	NA	NA	NA
WP_035067854.1\|395970_396579_+	transglutaminase family protein	NA	NA	NA	NA
WP_035064544.1\|398191_398854_-\|tRNA	tRNA synthetase subunit beta	NA	NA	NA	NA
WP_035064548.1\|398914_400051_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_035064551.1\|400108_400966_+	amidase domain-containing protein	NA	NA	NA	NA
WP_019417166.1\|400968_401451_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_009373577.1\|401732_403628_+	PrkA family serine protein kinase	A0MN77	Thermus_phage	8.7e-104	36.8
WP_035064553.1\|403848_405018_+	sporulation protein YhbH	X2JIL8	Bacillus_phage	5.5e-24	45.5
WP_035064556.1\|405014_406568_-	recombinase family protein	D2XR37	Bacillus_phage	5.0e-150	59.1
WP_035064559.1\|406625_407105_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_035064562.1\|407186_407966_-	DUF1829 domain-containing protein	Q6SEA4	Lactobacillus_prophage	2.9e-37	36.4
WP_035064564.1\|407965_408412_-	hypothetical protein	Q4ZCB9	Staphylococcus_virus	3.0e-07	30.1
408475:408492	attL	NA	NA	NA	NA
WP_035064570.1\|409062_410613_-	restriction endonuclease	NA	NA	NA	NA
WP_035064573.1\|410712_411117_-	helix-turn-helix domain-containing protein	Q0H244	Geobacillus_phage	7.2e-16	45.2
WP_035064576.1\|411292_411520_+	helix-turn-helix transcriptional regulator	Q0H243	Geobacillus_phage	1.8e-16	60.9
WP_035064579.1\|411557_411899_+	hypothetical protein	NA	NA	NA	NA
WP_081957664.1\|411852_412113_-	hypothetical protein	NA	NA	NA	NA
WP_165551154.1\|412242_412419_+	hypothetical protein	NA	NA	NA	NA
WP_035064583.1\|412472_412994_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_009362114.1\|413007_413232_+	hypothetical protein	NA	NA	NA	NA
WP_165569754.1\|413245_413398_+	hypothetical protein	NA	NA	NA	NA
WP_035064586.1\|413664_413919_+	hypothetical protein	NA	NA	NA	NA
WP_035064587.1\|413923_414256_+	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_128713007.1\|414266_414470_+	hypothetical protein	NA	NA	NA	NA
WP_035064590.1\|414532_415525_+	DnaD domain protein	A0A0U4JX08	Bacillus_phage	6.7e-39	71.2
WP_019417148.1\|415534_415735_+	hypothetical protein	NA	NA	NA	NA
WP_081957666.1\|415740_415902_+	Fur-regulated basic protein FbpA	NA	NA	NA	NA
WP_165569755.1\|415995_416160_+	hypothetical protein	NA	NA	NA	NA
WP_035064592.1\|416159_416639_+	hypothetical protein	S6AVW3	Thermus_phage	1.8e-34	50.0
WP_035064595.1\|416640_416901_+	hypothetical protein	S6BFL9	Thermus_phage	4.9e-18	75.9
WP_035064598.1\|417256_417466_+	hypothetical protein	NA	NA	NA	NA
WP_035064601.1\|417505_417700_+	hypothetical protein	NA	NA	NA	NA
WP_035064604.1\|417921_418203_+	hypothetical protein	NA	NA	NA	NA
WP_049720853.1\|418244_418505_+	hypothetical protein	NA	NA	NA	NA
WP_035064606.1\|418516_419251_+	antirepressor	A0A2P1JTZ2	Anoxybacillus_phage	9.4e-115	79.3
WP_035064609.1\|419387_419582_+	hypothetical protein	NA	NA	NA	NA
WP_035064612.1\|419605_420049_+	ArpU family transcriptional regulator	Q0H270	Geobacillus_phage	3.1e-36	58.1
WP_035064614.1\|420045_420588_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	1.1e-59	63.3
WP_035064616.1\|420739_421033_+	hypothetical protein	NA	NA	NA	NA
WP_035064619.1\|421249_421690_+	hypothetical protein	NA	NA	NA	NA
WP_035064622.1\|422536_424360_+\|terminase	phage terminase large subunit family protein	A0A0C5ABH4	Bacteriophage	1.3e-194	57.8
WP_035064625.1\|424378_424609_+	hypothetical protein	A0A067ZJ01	Vibrio_phage	1.0e-19	64.9
WP_049720927.1\|424608_426126_+\|portal	phage portal protein	A0A067ZJA4	Vibrio_phage	1.6e-172	61.2
WP_035064629.1\|426109_427192_+\|protease	Clp protease ClpP	A0A067ZG37	Vibrio_phage	4.1e-74	43.6
WP_035064631.1\|427191_427551_+\|head	head decoration protein	A0A067ZIL6	Vibrio_phage	4.7e-27	53.0
WP_081957699.1\|427571_428582_+\|capsid	major capsid protein	A0A0C5ABI0	Bacteriophage	3.3e-94	51.8
WP_035064637.1\|428595_429066_+	hypothetical protein	NA	NA	NA	NA
WP_035064640.1\|429058_429388_+	hypothetical protein	NA	NA	NA	NA
WP_035064642.1\|429397_429952_+	hypothetical protein	NA	NA	NA	NA
WP_035064644.1\|429951_430437_+	hypothetical protein	NA	NA	NA	NA
WP_035064647.1\|430426_430726_+	hypothetical protein	NA	NA	NA	NA
WP_035064649.1\|430729_432190_+\|tail	phage tail sheath family protein	A0A067ZJ07	Vibrio_phage	2.5e-151	54.2
WP_035064652.1\|432201_432729_+\|tail	phage major tail tube protein	A0A067ZJA9	Vibrio_phage	2.8e-36	44.8
WP_035064655.1\|432749_433055_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_049720854.1\|433177_435514_+\|tail	phage tail tape measure protein	V5YUN9	Pseudomonas_phage	8.9e-74	36.4
WP_035064658.1\|435506_435725_+	hypothetical protein	A0A067ZJB1	Vibrio_phage	2.3e-08	50.0
WP_049720855.1\|435721_436741_+	hypothetical protein	A0A0C5AJ59	Bacteriophage	1.0e-58	40.1
WP_128713009.1\|436737_437202_+\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	8.0e-19	44.3
WP_049720857.1\|437201_437864_+	SH3 domain-containing protein	A0A0C5AN08	Bacteriophage	4.2e-21	39.4
WP_035064663.1\|437869_438178_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_035064666.1\|438164_439283_+\|plate	baseplate J/gp47 family protein	A0A067ZJB4	Vibrio_phage	2.4e-85	43.6
WP_035064669.1\|439275_439839_+\|tail	phage tail protein I	A0A0C5AJ63	Bacteriophage	7.6e-48	52.2
WP_128713015.1\|440548_441451_+	hypothetical protein	A0A1L2K2Q1	Aeribacillus_phage	4.6e-63	81.1
WP_035064671.1\|441447_442410_+	hypothetical protein	NA	NA	NA	NA
WP_035064673.1\|442417_442753_+	hypothetical protein	A0A0K2CNW8	Brevibacillus_phage	4.7e-05	34.7
WP_165569756.1\|442754_442892_+	hypothetical protein	A0A1B1P890	Bacillus_phage	2.0e-10	74.4
WP_035064675.1\|442963_443383_+\|holin	phage holin family protein	S6AVT9	Thermus_phage	2.1e-63	94.2
WP_035064677.1\|443379_444048_+	LysM peptidoglycan-binding domain-containing protein	S6BFI4	Thermus_phage	5.6e-122	93.7
WP_035064679.1\|444162_444384_+	hypothetical protein	A0A1L2JZ89	Aeribacillus_phage	6.1e-09	42.0
WP_035064681.1\|444569_445301_+	DUF3800 domain-containing protein	Q71TB8	Escherichia_phage	3.8e-55	47.2
WP_035064682.1\|445297_445954_+	hypothetical protein	NA	NA	NA	NA
WP_049720858.1\|446156_446420_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_156185731.1\|446935_447277_+	hypothetical protein	NA	NA	NA	NA
WP_009362057.1\|447650_447950_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_009362056.1\|447961_448537_+	redox protein, regulator of disulfide bond formation	NA	NA	NA	NA
WP_009362055.1\|448533_448929_+	peroxiredoxin family protein	NA	NA	NA	NA
WP_009362054.1\|448940_449168_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_009362053.1\|449216_449993_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_009362052.1\|450075_450309_+	glutaredoxin family protein	NA	NA	NA	NA
WP_009362051.1\|450361_451495_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_035064684.1\|451648_452335_+	peptidase	NA	NA	NA	NA
WP_035065167.1\|452381_453719_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_035064687.1\|453713_454625_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_009362047.1\|454730_455120_+	DUF5365 family protein	NA	NA	NA	NA
WP_019417092.1\|455143_455608_-	thioredoxin family protein	NA	NA	NA	NA
WP_035064691.1\|455604_456033_-	disulfide bond formation protein B	NA	NA	NA	NA
WP_035065170.1\|456163_456592_+	CBS domain-containing protein	A0A2I6B2H4	Macacine_betaherpesvirus	6.7e-12	34.3
WP_035064693.1\|456852_458592_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.1e-156	48.8
WP_009362042.1\|458664_459372_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004892205.1\|459397_459649_-	hypothetical protein	NA	NA	NA	NA
WP_009362041.1\|459749_460202_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.2e-24	38.4
WP_035064696.1\|460206_461139_-\|protease	protease modulator HflC	NA	NA	NA	NA
460916:460933	attR	NA	NA	NA	NA
WP_035064699.1\|461135_462101_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA

DBSCAN-SWA_3

662463 : 686894

Bacillus_virus(25.0%)

transposase,integrase,holin,coat

attL 663740:663757|attR 693845:693862

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_035065017.1\|662463_662727_+\|coat	spore coat protein regulator YlbO	NA	NA	NA	NA
WP_035065019.1\|662935_663127_+\|holin	holin	NA	NA	NA	NA
WP_035065022.1\|663210_663414_+	DUF1657 domain-containing protein	NA	NA	NA	NA
WP_035065025.1\|663472_663928_+	membrane protein	NA	NA	NA	NA
663740:663757	attL	NA	NA	NA	NA
WP_035065028.1\|663937_664420_+	stage V sporulation protein AC	NA	NA	NA	NA
WP_035065030.1\|664416_665433_+	stage V sporulation protein AD	NA	NA	NA	NA
WP_035065033.1\|665429_665786_+	stage V sporulation protein AE	NA	NA	NA	NA
WP_035065036.1\|665792_665999_+	DUF1657 domain-containing protein	NA	NA	NA	NA
WP_035065039.1\|666001_666859_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_035065042.1\|666890_667700_-	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_035065045.1\|668011_668329_-	thioredoxin family protein	NA	NA	NA	NA
WP_035065047.1\|668416_668653_+	hypothetical protein	NA	NA	NA	NA
WP_006322839.1\|668734_668863_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_006322845.1\|668949_669204_+	sporulation protein	NA	NA	NA	NA
WP_049720861.1\|669221_671372_-	ATP-dependent helicase	G3MA40	Bacillus_virus	1.0e-76	33.4
WP_035065053.1\|671454_671634_+	hypothetical protein	NA	NA	NA	NA
WP_035065056.1\|671731_672130_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.6e-52	72.7
WP_035065058.1\|672142_673252_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A288TXV8	Enterococcus_phage	1.5e-84	48.3
WP_035065190.1\|673375_674053_-	DUF421 domain-containing protein	NA	NA	NA	NA
WP_035065061.1\|674182_674614_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_021094697.1\|674618_675131_-	hypothetical protein	NA	NA	NA	NA
WP_035065064.1\|675190_675883_-	esterase family protein	NA	NA	NA	NA
WP_035065066.1\|675985_676501_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	2.1e-36	49.1
WP_035020866.1\|676603_676999_-	large conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_035065069.1\|677332_678103_-	dioxygenase	NA	NA	NA	NA
WP_035065071.1\|678225_678705_+	cupin domain-containing protein	Q2I8C5	Bacillus_phage	2.7e-46	62.6
WP_035065073.1\|678988_680092_+	methionine biosynthesis PLP-dependent protein	A0A0B5JD48	Pandoravirus	6.4e-14	26.6
WP_035065076.1\|680095_681235_+	cystathionine beta-lyase	NA	NA	NA	NA
WP_004891686.1\|681255_681792_-	HD domain-containing protein	NA	NA	NA	NA
WP_035065078.1\|681910_682543_+	hypothetical protein	NA	NA	NA	NA
WP_081957686.1\|682840_683755_+\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	9.9e-29	28.6
WP_035065083.1\|683772_683958_+	hypothetical protein	NA	NA	NA	NA
WP_035065085.1\|684124_684931_+	hypothetical protein	A0A2H4J7R7	uncultured_Caudovirales_phage	9.6e-20	48.9
WP_035065087.1\|685305_686403_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_035065089.1\|686672_686894_+\|holin	holin	NA	NA	NA	NA
693845:693862	attR	NA	NA	NA	NA

DBSCAN-SWA_4

695258 : 757313

Liberibacter_phage(13.33%)

transposase,portal,integrase

attL 698418:698462|attR 752596:752640

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_035065113.1\|695258_696569_+\|portal	phage portal protein	NA	NA	NA	NA
WP_035065116.1\|697189_697531_+	hypothetical protein	NA	NA	NA	NA
WP_035065119.1\|697687_698266_+	hypothetical protein	NA	NA	NA	NA
698418:698462	attL	NA	NA	NA	NA
WP_035065126.1\|698574_699729_-\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	1.0e-70	38.9
WP_128713014.1\|700794_701658_+	hypothetical protein	NA	NA	NA	NA
WP_035065129.1\|701768_702830_+	sorbosone dehydrogenase family protein	NA	NA	NA	NA
WP_035065133.1\|703542_703944_+	cytidine deaminase	NA	NA	NA	NA
WP_081957697.1\|704017_704269_+	hypothetical protein	NA	NA	NA	NA
WP_035065197.1\|704506_705535_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_035065135.1\|705588_705951_+	hypothetical protein	NA	NA	NA	NA
WP_049720862.1\|706103_706799_+	hypothetical protein	NA	NA	NA	NA
WP_035065138.1\|707014_708181_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	1.2e-34	28.2
WP_049720840.1\|708446_709895_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_035067778.1\|710501_711986_+	type I restriction-modification system subunit M	A0A220A2U4	Liberibacter_phage	1.1e-109	42.2
WP_049720863.1\|711975_713208_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_035067776.1\|713204_716159_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	2.2e-101	29.9
WP_035067785.1\|716207_717188_+	restriction endonuclease	NA	NA	NA	NA
WP_035067774.1\|717235_717964_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_035067772.1\|718435_718834_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_035067781.1\|719183_720833_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.5e-56	31.8
WP_035067768.1\|722576_722849_-	DUF3986 family protein	NA	NA	NA	NA
WP_049720865.1\|723172_723619_-	DMT family transporter	NA	NA	NA	NA
WP_049720866.1\|723617_723797_+	hypothetical protein	NA	NA	NA	NA
WP_035067766.1\|724454_724892_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_035067763.1\|724984_725497_-\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	4.1e-08	27.9
WP_035067761.1\|725851_726274_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_035067759.1\|726639_727893_+	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_035067483.1\|728876_729392_-\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	1.1e-08	29.5
WP_035067481.1\|729406_729937_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_035067478.1\|730293_732024_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.3e-50	29.1
WP_035067476.1\|732017_733814_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.8e-59	31.1
WP_035067474.1\|734571_735405_+	pirin family protein	NA	NA	NA	NA
WP_035067472.1\|735559_736294_+	metallophosphoesterase family protein	NA	NA	NA	NA
WP_035067470.1\|736622_737285_+	HD domain-containing protein	S4W232	Pandoravirus	2.9e-14	32.1
WP_035067469.1\|737265_739164_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	4.7e-57	30.7
WP_035067467.1\|739182_740322_+	virulence factor	NA	NA	NA	NA
WP_015863926.1\|742186_742555_+	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	1.1e-50	78.7
WP_035067453.1\|742547_744686_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	0.0e+00	85.0
WP_035067451.1\|745052_746129_-	iron-containing alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_035067449.1\|746272_747115_-	methionine ABC transporter ATPase	NA	NA	NA	NA
WP_035067447.1\|747153_747819_-	ABC transporter permease	NA	NA	NA	NA
WP_035067446.1\|747808_748822_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-30	37.7
WP_035067442.1\|749426_750977_+	bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_035067440.1\|751273_751561_+\|transposase	transposase	NA	NA	NA	NA
WP_128713030.1\|751560_752124_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	5.5e-30	43.3
WP_035067436.1\|753121_753892_-	3-hydroxybutyrate dehydrogenase	NA	NA	NA	NA
752596:752640	attR	NA	NA	NA	NA
WP_019418695.1\|753904_755227_-	GntP family permease	NA	NA	NA	NA
WP_035067434.1\|755450_756800_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_081957764.1\|757025_757313_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1726624 : 1768790

Bacillus_phage(45.45%)

transposase,protease,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019417634.1\|1726624_1727299_+\|protease	intramembrane metalloprotease PrsW	NA	NA	NA	NA
WP_026011665.1\|1727341_1728247_+	spore cortex-lytic enzyme	A0A0E3XAL9	Bacillus_phage	4.3e-24	46.7
WP_019417636.1\|1728259_1729606_+	germination protein YpeB	NA	NA	NA	NA
WP_035066952.1\|1729617_1730982_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	NA	NA	NA	NA
WP_019417638.1\|1730957_1731626_-	dethiobiotin synthase	NA	NA	NA	NA
WP_009373711.1\|1731702_1732683_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_006319394.1\|1732752_1734018_-	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_049720892.1\|1734170_1734887_+	N-acetylglucosaminylphosphatidylinositol deacetylase	NA	NA	NA	NA
WP_009373715.1\|1734913_1735501_-	genetic competence negative regulator	NA	NA	NA	NA
WP_019418541.1\|1735582_1736503_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_009373720.1\|1736585_1737344_-	calcineurin-like phosphohydrolase	NA	NA	NA	NA
WP_035066950.1\|1737345_1737720_-	hypothetical protein	NA	NA	NA	NA
WP_009373723.1\|1737838_1738075_+\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
WP_009373725.1\|1738058_1738319_+\|coat	spore coat protein CotJB	NA	NA	NA	NA
WP_009373727.1\|1738336_1738906_+\|coat	component of the inner spore coat	NA	NA	NA	NA
WP_009373730.1\|1738906_1739344_-	YpbF family protein	NA	NA	NA	NA
WP_009373731.1\|1739404_1739926_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_019418536.1\|1739918_1740509_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_009373734.1\|1740505_1741948_-	ATP-dependent DNA helicase RecQ	F2NZ48	Diadromus_pulchellus_ascovirus	1.6e-57	40.8
WP_035066945.1\|1741940_1742963_-	hypothetical protein	NA	NA	NA	NA
WP_003394452.1\|1743163_1743412_+	ferredoxin	A0A127AYY7	Bacillus_phage	1.9e-19	54.7
WP_019418534.1\|1743530_1744031_+	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	2.7e-28	45.5
WP_035066943.1\|1744200_1745775_+	phosphoglycerate dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	8.7e-33	31.3
WP_009373738.1\|1745803_1746616_-	histidinol-phosphatase	NA	NA	NA	NA
WP_035066941.1\|1746840_1747542_-	hypothetical protein	NA	NA	NA	NA
WP_019418532.1\|1747534_1748005_-	ECF transporter S component	NA	NA	NA	NA
WP_009373741.1\|1748001_1748589_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_035066939.1\|1748599_1749025_-	cobalamin biosynthesis protein CobU	NA	NA	NA	NA
WP_035066937.1\|1748976_1749573_-	phosphoglycerate mutase	NA	NA	NA	NA
WP_035066935.1\|1749530_1750280_-	adenosylcobinamide-GDP ribazoletransferase	NA	NA	NA	NA
WP_035066934.1\|1750258_1750810_-	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	NA	NA	NA	NA
WP_035066932.1\|1750806_1751856_-	threonine-phosphate decarboxylase	A0A1X6WGT4	Pacmanvirus	1.8e-10	24.8
WP_035066930.1\|1751830_1752763_-	cobalamin biosynthesis protein	NA	NA	NA	NA
WP_035066928.1\|1752759_1754217_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.3e-11	29.8
WP_019418524.1\|1754207_1755254_-	iron ABC transporter permease	NA	NA	NA	NA
WP_019418523.1\|1755219_1756176_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_019418522.1\|1756554_1758318_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	2.9e-37	35.2
WP_009373760.1\|1758314_1759031_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.9e-43	41.7
WP_009373761.1\|1759180_1760356_-	c-type cytochrome biogenesis protein CcsB	NA	NA	NA	NA
WP_035066926.1\|1760368_1761985_-	cytochrome c biogenesis protein	NA	NA	NA	NA
WP_035066924.1\|1761997_1762519_-	thiol-disulfide oxidoreductase ResA	NA	NA	NA	NA
WP_009373764.1\|1762612_1763350_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_012574675.1\|1763429_1763963_-	spore maturation protein	NA	NA	NA	NA
WP_009373766.1\|1763962_1764556_-	spore maturation protein	NA	NA	NA	NA
WP_035066921.1\|1764548_1765661_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.1e-21	32.6
WP_035066919.1\|1765730_1766507_-	superoxide dismutase	NA	NA	NA	NA
WP_035066918.1\|1766565_1767054_-	YpuI family protein	NA	NA	NA	NA
WP_035066916.1\|1767067_1767487_-	hypothetical protein	NA	NA	NA	NA
WP_035066914.1\|1767650_1768790_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D2XQ03	Bacillus_virus	4.7e-121	59.4

DBSCAN-SWA_6

1775092 : 1780817

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033383623.1\|1775092_1775680_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.8e-15	37.3
WP_049720893.1\|1775679_1776456_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.8e-08	25.2
WP_019418512.1\|1776456_1776984_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_019418511.1\|1776990_1777335_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_019418510.1\|1777417_1777882_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.2e-43	61.7
WP_035066902.1\|1777896_1779090_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.5e-120	54.6
WP_026011839.1\|1779096_1779735_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	4.4e-44	44.3
WP_035066900.1\|1779740_1780817_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.8e-61	38.6

DBSCAN-SWA_7

2461025 : 2466444

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081957734.1\|2461025_2461661_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.3e-51	54.3
WP_035066245.1\|2461689_2461947_-	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_009362294.1\|2461966_2462929_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.9e-51	39.0
WP_019417457.1\|2462941_2463907_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.8e-57	44.9
WP_035066241.1\|2463903_2464794_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	9.4e-08	33.6
WP_009362297.1\|2464811_2465270_-	8-oxo-dGTP diphosphatase	A0A1S6UAL7	Serratia_phage	6.5e-05	30.2
WP_009362298.1\|2465496_2466444_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	5.5e-91	55.4

DBSCAN-SWA_8

2486425 : 2494062

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_035066194.1\|2486425_2487862_-	PDZ domain-containing protein	A0A0R6PIZ1	Moraxella_phage	1.8e-24	31.5
WP_035066193.1\|2488038_2489301_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2D0ZM66	Rhodococcus_phage	3.9e-15	39.0
WP_035066190.1\|2489320_2490214_-	ABC transporter permease	NA	NA	NA	NA
WP_009362324.1\|2490203_2490890_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	5.9e-26	35.0
WP_009362325.1\|2491050_2491377_-	cytochrome c	NA	NA	NA	NA
WP_035066187.1\|2491435_2492296_-	YitT family protein	NA	NA	NA	NA
WP_020424541.1\|2492385_2492646_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A125RQ76	Bacillus_phage	5.3e-28	69.8
WP_081957733.1\|2492614_2492944_-	hypothetical protein	A0A125RQ77	Bacillus_phage	2.3e-12	43.5
WP_128713022.1\|2492954_2494062_-	peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	1.1e-05	40.7

DBSCAN-SWA_9

2546483 : 2563021

Bacillus_phage(100.0%)

transposase,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012576101.1\|2546483_2547206_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_012576102.1\|2547216_2548875_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_035066089.1\|2548887_2551083_-	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	6.4e-58	30.1
WP_075039767.1\|2551561_2551804_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_128713019.1\|2551881_2552115_-\|bacteriocin	bacteriocin, lactococcin A1 family protein	NA	NA	NA	NA
WP_012576108.1\|2552616_2552826_-\|bacteriocin	bacteriocin, lactococcin A1 family	NA	NA	NA	NA
WP_019417539.1\|2553054_2554032_+	alpha/beta hydrolase family protein	NA	NA	NA	NA
WP_049720885.1\|2554582_2556031_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_035067548.1\|2557000_2557642_+	response regulator transcription factor	NA	NA	NA	NA
WP_012576112.1\|2558493_2558928_+	hypothetical protein	NA	NA	NA	NA
WP_035067546.1\|2559172_2559553_+	hypothetical protein	NA	NA	NA	NA
WP_049720911.1\|2561602_2562001_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_035067544.1\|2561957_2562200_-	hypothetical protein	NA	NA	NA	NA
WP_165569768.1\|2562679_2563021_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	2.0e-19	52.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012152

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection