CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012369	Moorella thermoacetica strain DSM 521 chromosome, complete genome	3 crisprs	csa3,cas2,cas1,cas4,cas7,cas8c,cas5,cas3,WYL,DinG,cas6,RT	0	3	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012369_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012369_1

420191-421882

TypeI

I-C,III-B

Consensus_repeat	Method
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	PILER-CR
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	CRISPRCasFinder
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	CRT

23 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3,WYL

The CRISPR arrays of NZ_CP012369_1

>merge|NZ_CP012369|1|420191-421882|PILER-CR,CRISPRCasFinder,CRT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGCTATGGATTTTGAGTCTGCCATGGCTGATGTTAGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGGCTGGTCAAAGTAAACCCCTCCGGCACTTCGCAGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGTGCACAACAAAGCGGCAGAGATGGGGCTTAAACGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACTGATTTATCCTGTGCCCTTGGAAGAGACACAAAAGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGTATTAGCGCTGATGTCGCTATCAAGGCCCTTGTGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACATGAGATTTTTGTTTTGCGTTTCCTGCGCGACCAGGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGATTCTGTTGGATGGCAAAGCTTACTTAGTGGTTGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACTAGGCCCTCCAGGTAGCCGTTAATGGCAGCGCAGAGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGCCCACGAGGTTTATGAAAATGATTATTTTGTGCTGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACTTGACGGCCTGAACCCCCATATGGCCGTGATCGATGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGTCATTGGCGAGTCAGGACAGGTATATGTAGACATTGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGACCGAATTTCGGCTCCGCTGCGGACTATAGAAAGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGACAATAGGCAGCATATGCCCCCGTATTCGGATTCGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGGCTATTTGGCAAAACGATTGAGATGATACAAGATGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGACCTTCCGGTGGTCCTCTAGCTTCCGGCCCTGCAGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACTTGCGTATCAGACGAAGGGTTAAAAGCACCGTCAGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACTTTCGGCTTCGGGGCCTTATATTCCTTGCCATCCAGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGTAGATCCATATCCGATCAAGTCCAAGAATATGTTGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGCACCTTCACCTGCTTAAATTATACCACATTTCCAGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACATTTGTTCGCCATTTGAAAGAGTGGCGAACGAGTGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACCTCTCGCCCGAAAAAAATCCTCAAAAAATTTTTCGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACATTAGACGGTCTTACCAAAGGTCTAATCAGGACAGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGACGATACGCCAGGCTGTGCAAGCCTTTCGGCTATACGGTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC

>NZ_CP012369|1|1|420191-421882|PILER-CR
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCTATGGATTTTGAGTCTGCCATGGCTGATGTTAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GGCTGGTCAAAGTAAACCCCTCCGGCACTTCGCAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTGCACAACAAAGCGGCAGAGATGGGGCTTAAACG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TGATTTATCCTGTGCCCTTGGAAGAGACACAAAAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTATTAGCGCTGATGTCGCTATCAAGGCCCTTGTG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATGAGATTTTTGTTTTGCGTTTCCTGCGCGACCAGG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GATTCTGTTGGATGGCAAAGCTTACTTAGTGGTT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TAGGCCCTCCAGGTAGCCGTTAATGGCAGCGCAGA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCCCACGAGGTTTATGAAAATGATTATTTTGTGCT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTGACGGCCTGAACCCCCATATGGCCGTGATCGAT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTCATTGGCGAGTCAGGACAGGTATATGTAGACATT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACCGAATTTCGGCTCCGCTGCGGACTATAGAAA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACAATAGGCAGCATATGCCCCCGTATTCGGATTCG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GGCTATTTGGCAAAACGATTGAGATGATACAAGAT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACCTTCCGGTGGTCCTCTAGCTTCCGGCCCTGCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTGCGTATCAGACGAAGGGTTAAAAGCACCGTCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTTCGGCTTCGGGGCCTTATATTCCTTGCCATCCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTAGATCCATATCCGATCAAGTCCAAGAATATGTT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCACCTTCACCTGCTTAAATTATACCACATTTCCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATTTGTTCGCCATTTGAAAGAGTGGCGAACGAGT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	CTCTCGCCCGAAAAAAATCCTCAAAAAATTTTTCG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATTAGACGGTCTTACCAAAGGTCTAATCAGGACAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GATACGCCAGGCTGTGCAAGCCTTTCGGCTATACG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC

>NZ_CP012369|1|1|420191-421882|CRISPRCasFinder
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCTATGGATTTTGAGTCTGCCATGGCTGATGTTAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GGCTGGTCAAAGTAAACCCCTCCGGCACTTCGCAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTGCACAACAAAGCGGCAGAGATGGGGCTTAAACG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TGATTTATCCTGTGCCCTTGGAAGAGACACAAAAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTATTAGCGCTGATGTCGCTATCAAGGCCCTTGTG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATGAGATTTTTGTTTTGCGTTTCCTGCGCGACCAGG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GATTCTGTTGGATGGCAAAGCTTACTTAGTGGTT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TAGGCCCTCCAGGTAGCCGTTAATGGCAGCGCAGA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCCCACGAGGTTTATGAAAATGATTATTTTGTGCT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTGACGGCCTGAACCCCCATATGGCCGTGATCGAT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTCATTGGCGAGTCAGGACAGGTATATGTAGACATT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACCGAATTTCGGCTCCGCTGCGGACTATAGAAA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACAATAGGCAGCATATGCCCCCGTATTCGGATTCG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GGCTATTTGGCAAAACGATTGAGATGATACAAGAT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACCTTCCGGTGGTCCTCTAGCTTCCGGCCCTGCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTGCGTATCAGACGAAGGGTTAAAAGCACCGTCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTTCGGCTTCGGGGCCTTATATTCCTTGCCATCCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTAGATCCATATCCGATCAAGTCCAAGAATATGTT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCACCTTCACCTGCTTAAATTATACCACATTTCCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATTTGTTCGCCATTTGAAAGAGTGGCGAACGAGT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	CTCTCGCCCGAAAAAAATCCTCAAAAAATTTTTCG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATTAGACGGTCTTACCAAAGGTCTAATCAGGACAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GATACGCCAGGCTGTGCAAGCCTTTCGGCTATACG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC

>NZ_CP012369|1|1|420191-421882|CRT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCTATGGATTTTGAGTCTGCCATGGCTGATGTTAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GGCTGGTCAAAGTAAACCCCTCCGGCACTTCGCAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTGCACAACAAAGCGGCAGAGATGGGGCTTAAACG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TGATTTATCCTGTGCCCTTGGAAGAGACACAAAAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTATTAGCGCTGATGTCGCTATCAAGGCCCTTGTG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATGAGATTTTTGTTTTGCGTTTCCTGCGCGACCAGG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GATTCTGTTGGATGGCAAAGCTTACTTAGTGGTT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TAGGCCCTCCAGGTAGCCGTTAATGGCAGCGCAGA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCCCACGAGGTTTATGAAAATGATTATTTTGTGCT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTGACGGCCTGAACCCCCATATGGCCGTGATCGAT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTCATTGGCGAGTCAGGACAGGTATATGTAGACATT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACCGAATTTCGGCTCCGCTGCGGACTATAGAAA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACAATAGGCAGCATATGCCCCCGTATTCGGATTCG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GGCTATTTGGCAAAACGATTGAGATGATACAAGAT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GACCTTCCGGTGGTCCTCTAGCTTCCGGCCCTGCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTGCGTATCAGACGAAGGGTTAAAAGCACCGTCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	TTTCGGCTTCGGGGCCTTATATTCCTTGCCATCCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GTAGATCCATATCCGATCAAGTCCAAGAATATGTT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GCACCTTCACCTGCTTAAATTATACCACATTTCCA
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATTTGTTCGCCATTTGAAAGAGTGGCGAACGAGT
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	CTCTCGCCCGAAAAAAATCCTCAAAAAATTTTTCG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	ATTAGACGGTCTTACCAAAGGTCTAATCAGGACAG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC	GATACGCCAGGCTGTGCAAGCCTTTCGGCTATACG
GTTTCAACCCTCGCCCGGCATGGAAGCCGGGCGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012369.1\|WP_011392031.1\|423479_424124_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
NZ_CP012369.1\|WP_011392027.1\|415254_418878_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379260
NZ_CP012369.1\|WP_053094611.1\|402860_406316_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CP012369.1\|WP_011392032.1\|424207_425101_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
NZ_CP012369.1\|WP_011392036.1\|430028_430718_+\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP012369.1\|WP_158499094.1\|430677_430851_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP012369.1\|WP_011392034.1\|426885_427587_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NZ_CP012369.1\|WP_011392030.1\|422376_423408_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP012369.1\|WP_162490020.1\|411239_411545_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368753
NZ_CP012369.1\|WP_011392035.1\|427648_429823_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NZ_CP012369.1\|WP_011392020.1\|410735_410957_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NZ_CP012369.1\|WP_011392023.1\|411764_412580_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012369.1\|WP_011392019.1\|406325_410543_+\|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl\|CDD\|274299
NZ_CP012369.1\|WP_011392026.1\|414674_415286_+\|DUF4194-domain-containing-protein	unknown	unknown	gnl\|CDD\|372745
NZ_CP012369.1\|WP_071549582.1\|418810_420142_+\|DUF2399-domain-containing-protein	unknown	unknown	gnl\|CDD\|173774
NZ_CP012369.1\|WP_011392033.1\|425193_426876_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP012369.1\|WP_011392021.1\|410953_411190_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|224638
NZ_CP012369.1\|WP_158499095.1\|431178_431343_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012369.1\|WP_011392029.1\|422053_422344_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP012369.1\|WP_011392025.1\|413124_414582_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP012369.1\|WP_011392020.1\|410735_410957_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	7.41698e-15
NZ_CP012369.1\|WP_011392027.1\|415254_418878_+\|AAA-family-ATPase	gnl\|CDD\|379260	pfam13558, SbcCD_C, Putative exonuclease SbcCD, C subunit. Possible exonuclease SbcCD, C subunit, on AAA proteins.	1.80869e-22
NZ_CP012369.1\|WP_011392033.1\|425193_426876_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	0
NZ_CP012369.1\|WP_011392032.1\|424207_425101_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	7.03954e-140
NZ_CP012369.1\|WP_011392036.1\|430028_430718_+\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.56463e-30
NZ_CP012369.1\|WP_158499094.1\|430677_430851_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.35898e-10
NZ_CP012369.1\|WP_011392030.1\|422376_423408_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP012369.1\|WP_011392031.1\|423479_424124_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	5.2136e-38
NZ_CP012369.1\|WP_011392035.1\|427648_429823_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	4.83896e-60
NZ_CP012369.1\|WP_162490020.1\|411239_411545_+\|hypothetical-protein	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	0.00359225
NZ_CP012369.1\|WP_053094611.1\|402860_406316_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP012369.1\|WP_011392019.1\|406325_410543_+\|UvrD-helicase-domain-containing-protein	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP012369.1\|WP_011392026.1\|414674_415286_+\|DUF4194-domain-containing-protein	gnl\|CDD\|372745	pfam13835, DUF4194, Domain of unknown function (DUF4194).	7.76926e-31
NZ_CP012369.1\|WP_071549582.1\|418810_420142_+\|DUF2399-domain-containing-protein	gnl\|CDD\|173774	cd00223, TOPRIM_TopoIIB_SPO, TOPRIM_TopoIIB_SPO: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IIB family of DNA topoisomerases and Spo11. This subgroup contains proteins similar to Sulfolobus shibatae topoisomerase VI (TopoVI) and Saccharomyces cerevisiae meiotic recombination factor: Spo11. Type II DNA topoisomerases catalyze the ATP-dependent transport of one DNA duplex through another, in the process generating transient double strand breaks via covalent attachments to both DNA strands at the 5' positions. TopoVI enzymes are heterotetramers found in archaea and plants. Spo11 plays a role in generating the double strand breaks that initiate homologous recombination during meiosis. S. shibatae TopoVI relaxes both positive and negative supercoils, and in addition has a strong decatenase activity. The TOPRIM domain has two conserved motifs, one of which centers at a conserved glutamate and the other one at two conserved aspartates (DxD. For topoisomerases the conserved glutamate is believed to act as a general base in strand joining and, as a general acid in strand cleavage. The DXD motif may co-ordinate Mg2+, a cofactor required for full catalytic function.	2.40608e-25
NZ_CP012369.1\|WP_011392021.1\|410953_411190_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|224638	COG1724, COG1724, Predicted RNA binding protein (dsRBD-like fold), HicA family [General function prediction only].	2.30977e-18
NZ_CP012369.1\|WP_011392029.1\|422053_422344_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.30538e-28
NZ_CP012369.1\|WP_011392034.1\|426885_427587_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.30872e-94

>NZ_CP012369.1|WP_071549582.1|418810_420142_+|DUF2399-domain-containing-protein
MAGTGRDLQAQYRYRILSLLISKYEGSRSFQTGTPGKQRPQFAMKKSPLAGDYFDEMDHRKREAIHAALAELAAAGVVEVTWPRFQEGRQVEKVYLNFDAIPRAYELAGLVPRAERICRLRQVLAPLATHPWEWVRRWWAGVDASLGERRSAGLDLEDPEGYGELVKVLLALPGLEDSTPERIFSQRVLGDSKAFEQRVKKRLLALLKSYGPEEYETDAEYLDSVGLTDNPKMVLVAGPMTFRVGRTTVNVGGLPGGLGLAAHMVRAMEITAVTAPWVLLVENLTSYYQVVQSVSELAVPCREGGGGRGLAVEGPAGLVVYTGGFPHRGVQLFLRRLQDYRESPGATARPPVYHWGDMDYGGIRICEYIRRNLIPDLQPYLMDVTTYTRYLPAGIPFGDEYAARLRHLAEDPAYAPWHPLLQAMLKHRKWVEQESIAINVSWA
>NZ_CP012369.1|WP_011392027.1|415254_418878_+|AAA-family-ATPase
MKWMRRLRLINWHYFYDETLEFGRQTLIAGRNSAGKSTIIDALQVLLVANQRQIRFNSAAHDEARRSLISYLRGKTGGEERKYLREGDFTSYIVAEFYDQQKRENFVVGVVMDVYGDDTIDDEYFILSGVELADLDFWSPAERWKNREEFHRYCQNLPGRHIFERSKTGYQKALLNRLGQVSERFFPVFVKALSFKPIQNVRDFVYQYILDEKELQLDLLRQNFEIHERYQAELEALEERREQLEAICRQFDTFARLRDTVAIQEYVIRGLKHTREVELRDRLEEEIRFLTAEVERLGRELDLARAKQLEAGQKAREAYQKWQSHQARQREQELKEGLARVDKDLREQGRLLAILRQTLEREKALLAGLQEMEADEYWQWQPGERERLGRALELLSGLVPAGDADWLPGEDTVAAVRDTGLFLAGLHSRCARAVGRLEDRLALLQQQKAELEGQIRDLENKKRPYPPHVLNLKRLLEERLNRRSPVWIFCEEMDLKDETWRDAVEGYLYTQRFDLLVEPRVFAEALAIYEREKGKHQIEGVGLVDTEKEQKYLGTAQEGSLAEEMVTGNPVIQAHIDHLLGRVMKARDEQDLRRYRTAITRTCMSYHNLVARQLEKHRYAVPYIGARAIARQLEIKRRELAETKEQIEVLKDKREKLAAWLERLADKKSLYAGISEQLDLPARIRRLEEERAALAAELERLDLGEVERLKEEYYYWERRGKELLDEVTEISGLKKSRENELNQKQTELHLQETRVQEAQAFWQSWREQYPVELLPRAEERWREAAGQELPVASKLINWENSQKGNTTRREQEFQRLRDLRHEYNLRYTYNADPGAPDNEAYRPLLAEIATVDIPRYREKLAEALKQSEEEFKSHFIFKLREAIEAARRDFNELNYALKNFPFHEDRYHFEIKPSERYRRFYDVIMDPGVMEQGSLFELPEDDRTAVLHELFEKLIRGEAGELEEFTDYRNYLDFDIVVTSGEHRYSFSQVLREKSGGETQTPFYVAILASFNHLYDTGKTVRLVVFDEAFNKMDEERIQTSLRLIKRMNLQLIAAVPDEKMQHMAPEVDTTLLVHRNGFHCFVDMISRQEVLAGDEVPTGDGQPAGPGDTDGGRAGGHKEAGYGGTGGEDSGDAGDDADDAGNDGPPLNDAASLSRPAGGEDGHRGQAGGSGGEDSGRPRRGGVRNGRDGQRPASAVPVQDSLFADQ
>NZ_CP012369.1|WP_011392026.1|414674_415286_+|DUF4194-domain-containing-protein
MLNLGENLSEQEAGRLREVINRLLAVNFLNKEQEREHYLVARRHRQVLEEFFRFLGWEIVFDDRHECLFVLSPEAGCRRNLTRDESIWLLVLRLIYQEKRQGLSLSEFPVTTLHEIRAKYEAFRLPLFNKTRLQELVRLGTQYKLLEPLNDDIRSDDCAFRLFHTLLYAVQADTVEKLYQKIAAYEQGKEELPNEVDAPPAVD
>NZ_CP012369.1|WP_011392025.1|413124_414582_+|hypothetical-protein
MKLFEVIPERLFQVFSGRNRYIYAEALLLLYEQYRVNRFGIQYEVMRDLMQELIESQEEAGLAFEVEEEQEQEPAASGLFNGDGEDQARLKAGVILRRLEKLKWIQVEVRENFRHYIVLPHYASRLLAVFQELCENRTVEYQRFAFVTYQLLSGEEARQRPGFAILEAQRMTQEFLEELRVLANNMKYHMEQVVAKTSIQEVLDHHFEEYKAHIIDRSYHRLKTSDHVSRYRQRILATVQEWLLDPEWMARAVEDALRNEFFATREEAAEQLRRALMDIEEIYRGLDEIFYQIDLRHNQYLRASFERARYLSQHSSGVDQYLARILEWMAAGIRRGDLPEEDCLPGMFNLMRLNQLNEQSLYTPRRRRAPHRPEPQVVVAVPEELKRQLREQNLQRVRQAITREKVSAYVLGRLGERREMGIEELAPTNMEEFLYLLYVYLYGYDGLAGYRLVPRGANRILDIGGYRFYDRRVVRVDTGRKGRAV
>NZ_CP012369.1|WP_011392023.1|411764_412580_+|hypothetical-protein
MKSYLTRLIVIIMILGIVMYVAGCSSANTTSTSKATQEVLKNDKLAELTTEPDKFKNYPVELTGKIFTAPEVKDGKTAFQMWGDPQKSEFNVVVYYNGTSNDIKSDNYVKVKGTVKGKFEGSNAFGAKITAVAIMADAVEKVNPVDIIAPAKLKIDVNKAANQKGYSITLQKVEFADNETRVYLAVKNETNNKIYFWEHSAKALQNNKQLDVKMNFDYPRVQPEILPGVVSEGVVVFPALDINAKSATFVFEGSSDDFNIRINPMSFDVSW
>NZ_CP012369.1|WP_162490020.1|411239_411545_+|hypothetical-protein
MTFFDTVLQGQAVSPMDYIKQSVKQLVEKYKTNDPYRLEQDMGIDVDEFPFRRIKGKVAIVLNSNLTEWLKRVVLVHELGHRQLSPQGAGYFFLAEHTLME
>NZ_CP012369.1|WP_011392021.1|410953_411190_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MRRLAIISAEDMERILIHLGFERKRQVGSHVMFAHPDGRCTVVPFRKGEDLARSLIRKILRDVDISPEEYEKLRQEIL
>NZ_CP012369.1|WP_011392020.1|410735_410957_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MASHCFLVVIEQDEDGKYIASVPSLPGCHTQADNLAELEERVQEAIKLYLNENSDFIPAPDKFIGIHQVEVQA
>NZ_CP012369.1|WP_011392019.1|406325_410543_+|UvrD-helicase-domain-containing-protein
MTATGKREWTPDQLAAIRARRANILVAAAAGAGKTAVLVERIIQRLTDPEDPVSLENLLVVTFTEAAAAEMRQRIGAALEAAVARDPENEALRRQLLLLNRAHISTIHSFCLWVLRTYFYRLDLDPGFRVMDPAEVDLMQLEVMDRVLEEAFAAEPDGGPVTDLADSLGGRGDANLVDLVLRVWEFSRSLPWPEAWLEQVTSSYKVTPETPLESLPWYGELRQMITLELQEAAWYLEQARQAAAAPGGPAVYLDNLENEKEQVTRLLEEVGDLPWEELNAKLAAVHFGRLKAARGEDVDPVLKERAGKLRNQARDLLYALKEDLCRDEAAVRAELERSGELVATLVGLVRRFDAALREAKGRRNLIDFSDLEHLCLRVLLDEGAGPGRLQPSDVALELRQRFAEVLVDEYQDINTVQDAILALVSRQDVAENNLFMVGDVKQSIYRFRLANPDLFLAKYRQYPEGEGGPNRRILLKANFRSRQGVVDGVNFIFRQVFSPLVGELEYDAAAALVGRAGYPENPAAATPAVEVYLQEGKVAAGTGAGGRTDLPEAVGAGKGGKISGGAGYGETLSGYGAASPGGETGAPDLEDLTALEREALLVARRIRRMVRGTPERPGPEFQVWDQEKKEYRDLTYRDIVILLRATRDRAPVFLEALKQYGIPAYADLGSGYFAATEIETILSLLRVIDNPHQDIPLAAVLRSPIVGLSAGDLARIRLAAPGEDFFTAVVKAAGAPLLPFTARESAAPSSTATGSGGALDNQPGQDPVCIAPYIEDTQEPWRDDHPGPGAAAGKAVPGKDRDLASLLREFLARLERWRTLARRQPLGDVIWQLYRETGYLEFVGGLPGGAQRQANLRALLDRARQFEGFARHGLFRFLRFIERLQQNEGDLGTARALGENEDVVRVMSIHRAKGLEFPVVIVAGLGKGFNLRDLSGDFLLHGRLGLVPLYLDAAAGIKYPTLPYLATGHRLRLEALSEELRILYVALTRAREKLILAGTVRDLPRQAENWCASLFLPGEQLPPVLTSRAGNPLDWLLPALARHPDAAAIRDLAGVGGGHLLPDPSSWQVEVVRGGELPDRGSEEPGVQVRVTAGYQGTESAGQQENPGLLCSGWPGGSRELAGAVTPVQETAGKTVAPPGSNIAEAGVEPGVSPPAGAVSPQDETGPTWLQQEVARRLAWTYPRQPLTALPVKLTVTDLKRRFDVFNEGETPLRPGENTFTRRPAFLQSHQGLTAAERGTATHLVLQHVDLSRPVTGESLAGLLQEMVEREILTPEQAAAVDIRAIVTFFAAPLGKRLLARWEQVKRELPFSLAVPAVELYPGLPAEAAAGEIILVQGIIDCLVEEEDGFLLLDFKTGRIPPDPLAAYREQVRFYTRAVETIFNRNVKEVHLYFLDGGVDFKVTS
>NZ_CP012369.1|WP_053094611.1|402860_406316_+|helicase-exonuclease-AddAB-subunit-AddB
MALRLVLGRAGSGKTRLCLEEIKAILAEGPAGPALIILTPEQATLQMELDLHRAAGVPGFSRVQVLSFRRLGWRVFQEAGGAARPHLGEMGKAMALRAVVSAHRDDLGLFAPLAGSPGFIEQLAHTIAELKLYRVTPADLDRILERYRETGREQTILARKLRDLALVYRELETYLAGRYLDPDDYLTLLAGRLPEAAFIRGARVWVDGFNGFTPQEEAVLQALMAVAEQVTVTLCLDPTLRHRRLGETELFHPTGETYHRLRQLALAAGVRVEDDVCLAGTPPRFREAPALAHLEAHFGRWPLRPFRGDAAGIRLVAAANRRVEVEAAAREILRLAREENLSWRQMAVLVRDLEPYHDLIVNTFRDFNIPLFIDRRRPVGHHPLVELVRAALEAVLEDWAYDPVFRYLKSDLVPVPREEIDLLENYVLAHGIRGRRWRDSRPWQYGNSRDLETPSPPGSAAGETINAIRERASCHLRRFDGALRGRQLTGREITAALFDLLQELGVPERLAAWSRQAAAAGDLDAAQEHEQIWEGLMDLLEELVLALGDTSLELEEYAAILDTGLESLKLRLIPPALDQVVAGTLDRSRQPELQAAFVLGVGEGVLPARLPEDATFSDREREELRAAGLELAPTGTLRLFHEEFLAYLALTRSRRYLWLSYPLADAEGKALSPSPLVRRLRQLLPGLREETAGTELPGGDDDLVYLTTPRQAAGHLARLLGRGRPLPPLWQEVYRWLHQDARGQKMLGLLEGGGYRNQVDPLEPELARGLYPRPLRLSISQLETFAGCPFRYFLSYGLGLQERRLYQVDPAGMGQFYHAALKLFVEELGRRGLDWGRLSDNEAAAIISQVVDSLAPALQHEILSSNARYGYLRKKLEQTLQRVMEVLNEHARRGEFRPLAVETSFGCRGKLPPLQLDAGPGRRVFLEGRVDRIDVARRQGRPYLRVIDYKSSPTTLDLTAVYYGLALQLPLYLRAALDAAPELLGEAAEPAGMLYFAVRNPLIRQRGPVGKEAAARLRRQELKMRGLLLDDVEVIKLMDREIAASPDLLPLRLNKDGSLRKGAPVAGREEMALLLDLALARAAELAGAILSGRVEISPYRRGQETACDFCPYRPVCAFDPQIPGSGYRRLGNLPGDFWQLAAAFLGSQMKG
>NZ_CP012369.1|WP_011392029.1|422053_422344_-|CRISPR-associated-endonuclease-Cas2
MYILITYDVSTETEAGKKRLRKVAQVCKDFGQRVQKSVFECSVNEAQFEQLKHRLLQCIDEKSDSLRIYRLREPAKKYIQEYGVNLTIDFDAPLVL
>NZ_CP012369.1|WP_011392030.1|422376_423408_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MHILLNTLYLMTPRTLVRLDHETVKIEVEGELKMQIPLHHLGSIVCFGDVTLTTPLIMRCAEDKRLIVFHDQHGRFKARVEGPVSGNVFLRHAQHEALSDSKKTTAIARNIVAGKIRNTRQVVLRGAREADNEDDRKALQETARELAHGLDALSRSPDLEQIRGIEGNAARHYFATLDRMVRVNREAFKITHRNRRPPLDRMNALLSYIYALLLNDCLSAAEGVGLDPQIGYLHVLRSGRPALALDLMEEFRAILADRLALTLVNRRQIDERDFVERPGGAVHINDNARKEIAIAYQKRKQEEVLHPVLNRKVPLGLVPHIQARLLARVLRGDAEEYLPFMYR
>NZ_CP012369.1|WP_011392031.1|423479_424124_-|CRISPR-associated-protein-Cas4
MESTILPGWDDRDIVMVSALEHYAYCPRQCALIHVEQTFTENMYTLKGRFVHNLVDVECGEMEGGVHIERALPIWSLRLGLIGKADVVEFHGNIPYPVEYKHGPKRKHQHDDLQVCAQAMCLEEMTGKQVPRGAIYHHSSHRRREVTFDSYLREQVEAAIIRIRMMQRSNILPPPAADERCRECSLQDSCLPQIKEKGRLRMLLCELFKPEGDT
>NZ_CP012369.1|WP_011392032.1|424207_425101_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTVYTNPEVRHDFVLLFDVRDGNPNGDPDAGNLPRLDPETMQGLVTDVCLKRKIRDWVDMTRGSEANMKIYVQHHGILNAQHQRAYDAIGEKSTGSKQNREIVDKARQWMCQNFYDIRMFGAVMTTGVNCGQVRGPMQLTFARSIDPIVPLDISITRVAITRVEDAATSEQGEGGKVTEMGRKTLVPYGLYLGYGFFNPHFAADTGVSAADLEIFWEALQRMWDVDRSASRGMMACRGLYIFSHASALGNAPADNLFKLITVKRRDGVKAARSFADYQVTINEEDLPPGVTLTRLVG
>NZ_CP012369.1|WP_011392033.1|425193_426876_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLESLREYSTRLDLPPVMYVKTPIRWFIDLDSQGNLLGFVSATGPETRGKDRGKIMYAPNIVRSSGVKPKLLADKGDYVLGLASEKSKLERVNECHRAFIDLVRQCAISTGNKSVQAVLRFLENWDPEGARLPEDFNPGDNLTFRVDGRLPIEDPDVQSFWADYTNPQEGEATTCLLCGQLKTPAERHPVKIKGIPGGQTAGMALVSANAAAFESYGLQASLIAPICYDCAERYGKAANALIENDATHLRLGSCIYLFWTRKPSNFSIASLLSNPQPEDVKALLAAVYTGRQADLEDDNLFYATALSSSGGRVAVRDWLETTLGDVKRNLGHYFALQRLVDAGGREGPPLGLFPLAWSTVREPKDLPPTTTRALLHFALKGGALPHWLLYEAIKRARAEKDQEKITRSRAALIKMVLFSQKPNLAEGSALEKLDTSNRNPAYLCGRLLAVLEGIQWSALPGIKATIVDRFYGTASTAPAAVFSRLLRGSQSHLGKLRKEKPGLYYYWQQALESILGNLSSFPPVLTLEEQGYFALGYYHQRAANREGTNSKEDGEETRP
>NZ_CP012369.1|WP_011392034.1|426885_427587_-|type-I-C-CRISPR-associated-protein-Cas5
MKSLAGAGSSDQAGVEGWLAVKVWGDLACFTRPEMKVERVSYPVMTPSAARGILEAIFWKPEFRWRVRQIEVLKPIRYFSILRNEVNDKMVVSTARGWARNGGGYYADQPQHRAQRHTLALREVAYIIRAEQVMAAHARDIHPAKYRDQFRRRVERGQCYHRPYLGCREFCAFFGPSSPADQPIKHSEYLGQMLLDLKYNSDGSGEGRPVFFNARLENGILRVPQDLYKEIGR
>NZ_CP012369.1|WP_011392035.1|427648_429823_-|CRISPR-associated-helicase/endonuclease-Cas3
MEQFLAHTANSQGKEQSLLDHLEAVANLTQKFNEPLGVPHIGYRTGLWHDLGKFHPEFQAYLQGEGGRRGPNHSSAGAMLASKYFEPLAFVIAGHHGGLPARAELKTRLKDKVQLKRYNTALQNARRVIPSLEPKQPLDMELPPFLQEGAGVDVASRVELFLRLLFSSLVDADFLDTERHFDPSLTKLRQKEASIANLWSLLAANQQRLMDKSGGHVNQIRREIYEHCCRAAELTPGFFSLTVPTGGGKTRSGMAFALLHALRYQKERIIVAIPYTSIIEQTADVYRDIFGNANVLEHHSAVAPPLDPENPTPEELWARLASENWDATLIVTTTVQLFESLFSDRSSSCRKLHNIANSVIILDEVQTLPVHLLEPILDVLQQLVHFYGVTVILCSATQPALETSPFFRGLQGVREIIPDPQKYFALLKRVGYQVPAGNEKWSWEQVAGVIRQSRQAMAVVNTKQDALALLEALDDPEALHLSTLLCGAHRRKVLQEVRRRLGNGRPCRLVATQVVEAGVDLDFPLVLRAVGPLDRIVQAAGRCNREGKLQEGRVIIFNPEEGCLPPGSYKTGTEIAATLLASVTGVDLHDPGLYRIYFQRLYQSCTLDAKGIQASRRSLNYPEVAQKFQMIEQRVVPVIVNYHEGPDDRRVDELISALRHRGVSRLIMRQLQPYLVNINAYTVNSLQREGVVQEIFPGLYEWLGGYDEIRGLVTTARDPEELVF
>NZ_CP012369.1|WP_011392036.1|430028_430718_+|WYL-domain-containing-protein
MATVLKRKSMGLANVSRQSLARIYFIHRWIAAGRYPNVAILAEHLEVSQRTVERDIQLLRDFFGAPIVYDTWHRGYRYEKTFSLPPLQLTEGEFLTIYLGQRLLSQFGGTPFGQILRNALAKLKAMLPETVSIDLECLERDISFGIEPLRGDTEQLVAVYGDLLMAIQERHSVQIIYYTASRDAVTERLIDPYHLRFFRGAWYVIAYCHYRREIRFFALDRIRQWSAGG
>NZ_CP012369.1|WP_158499094.1|430677_430851_+|WYL-domain-containing-protein
MPWTASASGLQEVKRWVLGFGSHAEVLAPPELRQEVSREATAMGRLYLHTGEEGAER
>NZ_CP012369.1|WP_158499095.1|431178_431343_-|hypothetical-protein
MAVNQDSAEISIIIEALERTNQGEERTSYYQATYQVGLENGKLKLLKGTASKIR

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Crispr_ID: NZ_CP012369_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012369_2

616943-617034

Orphan

Consensus_repeat	Method
GGGGCGCATGCTCTATGGCCTCTCCGGC	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP012369_2

>merge|NZ_CP012369|2|616943-617034|CRISPRCasFinder
GGGGCGCATGCTCTATGGCCTCTCCGGCTTGATTTGCCCTTGAGCGGAAGCCGGTAGAACCGGCGGGGCGCATGCTCTATGGCCTCTCCGGC

>NZ_CP012369|2|2|616943-617034|CRISPRCasFinder
GGGGCGCATGCTCTATGGCCTCTCCGGC	TTGATTTGCCCTTGAGCGGAAGCCGGTAGAACCGGC
GGGGCGCATGCTCTATGGCCTCTCCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012369.1\|WP_011392213.1\|615530_616661_-\|FIST-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|225825
NZ_CP012369.1\|WP_053094661.1\|627565_628831_+\|S-methyl-5-thioribose-kinase	unknown	unknown	gnl\|CDD\|236561
NZ_CP012369.1\|WP_053094658.1\|623888_624965_+\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380478
NZ_CP012369.1\|WP_011392214.1\|617397_618210_+\|response-regulator	unknown	unknown	gnl\|CDD\|333815
NZ_CP012369.1\|WP_011392219.1\|621157_622744_+\|AIR-synthase	unknown	unknown	gnl\|CDD\|100037
NZ_CP012369.1\|WP_053094659.1\|625025_626504_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP012369.1\|WP_025774110.1\|611376_611622_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|198034
NZ_CP012369.1\|WP_011392211.1\|612369_612768_+\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350247
NZ_CP012369.1\|WP_011392204.1\|606219_606840_+\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP012369.1\|WP_011392208.1\|610927_611389_-\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350305
NZ_CP012369.1\|WP_162490034.1\|618621_619542_+\|VanW-family-protein	unknown	unknown	gnl\|CDD\|377286
NZ_CP012369.1\|WP_053094656.1\|620535_621108_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012369.1\|WP_162490033.1\|607528_607798_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012369.1\|WP_053094653.1\|613016_615527_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|225116
NZ_CP012369.1\|WP_011392220.1\|623029_623830_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP012369.1\|WP_053094660.1\|626531_627524_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119321
NZ_CP012369.1\|WP_011392206.1\|607769_608246_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350305
NZ_CP012369.1\|WP_053094655.1\|619733_620288_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|215494
NZ_CP012369.1\|WP_053094652.1\|612109_612382_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|198034
NZ_CP012369.1\|WP_148844667.1\|610047_610596_+\|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224012

Protein	Function_ID	Function_description	E-value
NZ_CP012369.1\|WP_011392213.1\|615530_616661_-\|FIST-C-terminal-domain-containing-protein	gnl\|CDD\|225825	COG3287, COG3287, Uncharacterized conserved protein [Function unknown].	1.36558e-42
NZ_CP012369.1\|WP_053094661.1\|627565_628831_+\|S-methyl-5-thioribose-kinase	gnl\|CDD\|236561	PRK09550, mtnK, methylthioribose kinase; Reviewed.	0
NZ_CP012369.1\|WP_053094658.1\|623888_624965_+\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380478	cd01536, PBP1_ABC_sugar_binding-like, periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily. Periplasmic sugar-binding domain of active transport systems that are members of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this family function as the primary receptors for chemotaxis and transport of many sugar based solutes in bacteria and archaea. The sugar binding domain is also homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR. Moreover, this periplasmic binding domain, also known as Venus flytrap domain, undergoes transition from an open to a closed conformational state upon the binding of ligands such as lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. This family also includes the periplasmic binding domain of autoinducer-2 (AI-2) receptors such as LsrB and LuxP which are highly homologous to periplasmic pentose/hexose sugar-binding proteins.	1.62655e-76
NZ_CP012369.1\|WP_011392214.1\|617397_618210_+\|response-regulator	gnl\|CDD\|333815	pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.	3.87666e-28
NZ_CP012369.1\|WP_011392219.1\|621157_622744_+\|AIR-synthase	gnl\|CDD\|100037	cd06061, PurM-like1, AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.	3.18487e-120
NZ_CP012369.1\|WP_053094659.1\|625025_626504_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP012369.1\|WP_025774110.1\|611376_611622_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	1.31543e-09
NZ_CP012369.1\|WP_011392211.1\|612369_612768_+\|PIN-domain-containing-protein	gnl\|CDD\|350247	cd18680, PIN_MtVapC20-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC20 and related proteins. M. tuberculosis VapC20 inhibits translation by site-specific cleavage of the universally conserved Sarcin-Ricin loop in 23S rRNA. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1.	1.95362e-19
NZ_CP012369.1\|WP_011392204.1\|606219_606840_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	3.8028e-14
NZ_CP012369.1\|WP_011392208.1\|610927_611389_-\|PIN-domain-containing-protein	gnl\|CDD\|350305	cd18738, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.01328e-07
NZ_CP012369.1\|WP_162490034.1\|618621_619542_+\|VanW-family-protein	gnl\|CDD\|377286	pfam04294, VanW, VanW like protein. Family members include vancomycin resistance protein W (VanW). Genes encoding members of this family have been found in vancomycin resistance gene clusters vanB and vanG. The function of VanW is unknown.	7.98891e-64
NZ_CP012369.1\|WP_011392220.1\|623029_623830_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	8.56135e-89
NZ_CP012369.1\|WP_148844667.1\|610047_610596_+\|GDP-mannose-4,6-dehydratase	gnl\|CDD\|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	1.08094e-55
NZ_CP012369.1\|WP_053094653.1\|613016_615527_-\|PAS-domain-S-box-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	6.21458e-57
NZ_CP012369.1\|WP_053094660.1\|626531_627524_+\|ABC-transporter-permease	gnl\|CDD\|119321	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.	1.70409e-74
NZ_CP012369.1\|WP_011392206.1\|607769_608246_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350305	cd18738, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.02908e-39
NZ_CP012369.1\|WP_053094655.1\|619733_620288_+\|hypothetical-protein	gnl\|CDD\|215494	PLN02915, PLN02915, cellulose synthase A [UDP-forming], catalytic subunit.	0.0062982
NZ_CP012369.1\|WP_053094652.1\|612109_612382_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	1.264e-10

>NZ_CP012369.1|WP_011392213.1|615530_616661_-|FIST-C-terminal-domain-containing-protein
MRVGVGFSSANDPSAAGQVASEQAVRQSGSPVITLVLTTDNYDQERVLSAVKRVIGNSRLVGACVPGVIVNARLYKRGVGICTVSGEGVEAVTHLQRNISQHSYRKGEKAGEALLEKGGETPGTVLLFPDGFAANISGLLRGLYNVMGPAFEYIGGGSGDNLRFYRTYQFTEEGISSDAVAAAVIRGINFQMCLSHGWRPVGEPLMVTKAKGRKVYEIDGLPALERYSALVGAYDKNDFSCYSMKYPLGLPCAGGEFIIRDPLKAEEDGGILFVTEIPENTIATLMEGDTASLLAAAEEVSKKALNTPAAPKTFMVFDCVSRYLLMGEDFSREMEAIAKNIKAEIPVIGMLSFGEISSISGTPLFYNKTIVAAAGW
>NZ_CP012369.1|WP_053094653.1|613016_615527_-|PAS-domain-S-box-protein
MSFDISELLTLYDVVTFSFPERYEDLMREIIEKATRLFGVRRLAIVLREGERYKCIERWGFRRDEEVLERIKNGGENSFIYLMRNGEQGLLYIEPPGRISEREKRLYTIFARRIENIIARKQIEEKIKNSEQEKKVILDSIVELLVFQNPDNRILWANRAAAEYAGARSEELAGRFCYEALHHRDEPCEECPVIKALDTGVPQEGIIASLEGRQFFVRGYPVKKENGLIEGIVEVSVDVTERMQAEEAFRTIFNSVHDAIFIHTLDGKIIDVNQTMLRMYVINSKEEAIKLSIIDDYSIPGSTAEQLPLLWQKVISGENLLFEWKARRPVDGSVFDVEVFLKKISLSKKDVILAAVRDITERKREEELLRNLFTHSPIGMYIVSEGKFQLINPQFEILTGYRQDKLIGMESLNLVVPEDRKMVRSNAIKMLKGEAVEPYEFRIVTGQGDIRWMEETVASIWHDGKRVTLGNIIDITQKKKFEQKLAYISLHDQLTALYNRAYFEEELKRLSTSRKYPITIIVADVNGLKLVNDTMGHDKGDELLTACARVLKKAFRSLDVVARVGGDEFVALLPRTDGKTGKSILKRLRLFIDKYNQEHPELPLSVSFGIATADTPEQSLKEIYKKADDLMYQEKLNLGSSARSKIVNALLTALSERDYITEGHARRMQKLCQDLGEKVGLSAQQLANLSLLAQVHDLGKVGIPDRILFKRGPLTEKEWEVMRQHPEKGYRIAMSSPDLAGIADLILKHHEKWDGTGYPLGLKEEEIPIECRILSIVDAFDAMTSGRPYCRTKTIEDALKEIRRCAGTQFDPRLAEAFIEMITSEKFTAGEKKVAT
>NZ_CP012369.1|WP_011392211.1|612369_612768_+|PIN-domain-containing-protein
MEKIMVDTSAIYALIDRSDDRHEKAKHLFKKLSEQDVDLILTNFILAETHALILSCIGHELAREWVKNLIWKIERVKEEDEKRAREIIIAYQDKSFSYTDATTFAVMERLKLNIALAFDNHFTQFGWQCFDA
>NZ_CP012369.1|WP_053094652.1|612109_612382_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MSTQLVRLTSKGQMTIPQSVRETLGLKAGDYLTILVDEDEIRLRKVQPVKPLSQEDPIWKLVGAGNSGLKDVAAKHDHYLANGEIERWKK
>NZ_CP012369.1|WP_025774110.1|611376_611622_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MDIIKTVKLGARCQMVLPAEIRKQLGIKKGDEIIIKIRGKKAIIEPKPKSYAEHLWGLHKEVWAGTDPDKYVKEERDQWEK
>NZ_CP012369.1|WP_011392208.1|610927_611389_-|PIN-domain-containing-protein
MGKIKEIITGHQVIALDTNCFIYMLQADPWALVLKKELFNPLEKGEFQAVTSTLTLLELLVKPKALGLEEVCDQYITTLKSYPNLKLIDFNLEMAVLGAEIRAKYRVRTPDAIQLASALASDATLFFTNDLSLPQAVGNMRTVFLKDVFPPRA
>NZ_CP012369.1|WP_148844667.1|610047_610596_+|GDP-mannose-4,6-dehydratase
MADQAKFLGVPEKDIVLEKWAISTYENSLYSLMALGPGDRSGGPGYPYVISMPPGYRRQGILGRAVRDYIHVDDLAAAHVLALEALEQGSPTAAYNLGSGRGYSVLEVIRTAEKVTGKKVPCRVGPRRPGDQAVLVASAEKAMAELGWRPRYTELEDIIATAWQWHCRRPRGYSQGYSPAGR
>NZ_CP012369.1|WP_011392206.1|607769_608246_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MIDQGSYPNKYVVDTNIIIYTLAGVKAAVWAMKKLEDDDIEVYYSTIVEAELFSFHELTLEQKSKIRGILDIGEIVDVDSKVALKAAELRALSKKDYNRKLKLPDAIVAATALLLSAVLVTRNVEDFKHLRRHGLHLYNPFEHEEDNSQRFVSELEQN
>NZ_CP012369.1|WP_162490033.1|607528_607798_+|hypothetical-protein
MALLQVKRRVEPGGRIIIGEVLKMAKIKPGDWVEIIPGTNKITIKLTKRSKSKGAVLAAAGILKDHPQLVDEMLHIREDEDDRSGVVPE
>NZ_CP012369.1|WP_011392204.1|606219_606840_+|WYL-domain-containing-protein
MAIYRKCKYCGRPISLREMPAGQWVAFDVGTDNVHHCGSRPTITPPAVSAVAATLDTGTVTASPVVATSSEQIRALLKKALQEHRCVHLNYYTASRKALTDRVVEPLALEPGDWGGTILRAYCRWRQDIRSFALSNIRRAELLEETFSPRSLPQSQPITIYRTSISGRASIQASSKTPSTASESTGCIWWLIVVGVVLLWLLFGSR
>NZ_CP012369.1|WP_011392214.1|617397_618210_+|response-regulator
MLALPEKSVLLVEDSTLTRFSSRRVLEERGYLVDEAASGQEALVKARGKGEPYDLVILDIHLPGMDGLAVLENLKRLPEYRYVPVMVVTIESNVAVVKKAIDLGAVEYLCKPYSVEELVRRVEKLIGPGARREATPAELLHKVLRNEINRASRGALNVALVLARSEGLGKGKIVECARQARRRLREIDTVIELSKSTLALVLPHTGKEGAQVVITKLAGLLPGTWSYGVAVYPDNGKDGEELFAYAEASLKECWEKKTTGAPAQQQALDT
>NZ_CP012369.1|WP_162490034.1|618621_619542_+|VanW-family-protein
MMETALIRLPDDGQREMENLLRSFYWLVVLVAFFFAWPVLEPALAADPVVAYEDPDTQRAMIAVRDFSTVLGGEVDWEAATSTVSIRVYGRPALYLDVKAGTLAGVPLQPRPQIKDGVTYAPLRQVAEALGARVDWRKDGIHVYTPAGEQVSIKYIHLLGRYTITFPEKEAGSPSLHNARLAGQYLNGLVVPPGGVVSFNNVVGPRTGARGFVPGIIFMGDQKVPEIGGGICRTATLLHNAVLSAGLEVVERHRHGLPVTYVPPGYDATVYYGVLDYRFRNNRPVPIKLEFTSQGSSITMAIWELG
>NZ_CP012369.1|WP_053094655.1|619733_620288_+|hypothetical-protein
MYMKIITRNFKIVLKGKKEDFVDEALETRLFAFLSRIQAWGEAVTPDANLATVEQIDEEDTIPVSVDNELGVAREKAAAAKEAGDEEIMVHSQSISELRARATISNNKELATLVVYYSDYCKKQPPATYDVRRIMREELREKAATVNSVSTYLQRARREGWVDLDGKKWRITSTGLQMIEKMLR
>NZ_CP012369.1|WP_053094656.1|620535_621108_+|hypothetical-protein
MGVVYPWMRESLLSHLNCLVPVYHLDGSNYTEIWFDDGRKELEKNRTVTVLRRLARFLGINPRQNDTPWGRGGNRRATPIILFPELILVPLLLRRPRYRDQGGTGYVVLQKIIDWEAAEMDGYHSVIFLEGNQKLYSVQGYESLSQRLIEARKAGWKLQKLEKALNQGLLVSRQVMTIQVDKTTGEITFR
>NZ_CP012369.1|WP_011392219.1|621157_622744_+|AIR-synthase
MIGKVDDAFFRQAILPHTGAGDPEVVVGPRMGVDAAVLKIGEEYLAVAEDPIFPGPTTSPDDFGWITVHIGASDVAVMGIKPRFMTYSLLLPPGTPEDYIAGLVRSISTYARELGITIVGGHTGFYGAVTIPTIGGITVWGRGREVVTPAGARVGDAVIITKGAAIEAAALVACELGEKLLAAGISPDLVARAKKRLREMSVVAEAGIAVEVGGVHAMHDATEGGLARGLWEVAEASGVGLRIERARVPVPADIRAVCDYIGLNPYEVISEGTLVLTCAPEKADAMLAAFKEAGIEAAVIGRVVPAGAGRAWLEDDGREEQLLPPAVDRFWEVFFNALALKNDTRTPAEVALCRELGQAVRELEEANVAALIPEIGANLAYCLPEAKELRDIAAIPGRLLRFKGRVATLGEPEMGCSHHMGGTILVVREFFPQARCVINLRNNARVRQACADLGYKVVSMPVPPDYRQTDDDFYTDLRRTMAACRELPDVIEIPDRINLERLILVLGRNPGEIVSKVTSLATRVAELE
>NZ_CP012369.1|WP_011392220.1|623029_623830_+|DeoR/GlpR-transcriptional-regulator
MELVTNNDRNNDIAPQERRQLLFEYIYKNGSAKISELANRFNVSEMTIRRDIEVLEKKNLIMRTHGGVLYREGTIYDLGLAGNKVHLNEKIAIAKAARPLIEPGDLIAFDASTTGAELARLLNGIEDLTIVTNSLTVANIVAPYSNITLILVGGNLRSKALSTVGPLAADIVDHFNFTKMFFSCNAVDPVEGLTDTNVAEAEMKKIMLQRAGQRILLADSSKIGKRALVRFWPMEEIDIFVTDAGTPDEAVQVFQDLGVRVIRAEA
>NZ_CP012369.1|WP_053094658.1|623888_624965_+|sugar-ABC-transporter-substrate-binding-protein
MSIYEKGMNRREFIVKSLMASGLVAGSSLLLSGCSSGSTGTTAKEGKRLKAAFSNAGLQATWCAQGKDTVERWGKWLGVDITWYDGALSVDKQRAAVEDMATKDWDFVAIQPLGIGTLNEPVKKMLERGIPVIDMDTMIAQPGELPITCFIAPDNVWGAEQVTEALMQAIGGKGNVVMTQGSLGHTGAQGRAQGFHNVIKRYPDVKVIDETPADFDVNKVAQIWENLLNRYDKIDAAYFHNDDMALAAYQVIKNAGREKEIKIGGNDGMQPAVEAIQKGIMVATARNSAPRIHWGALMIGYYAATEKDANKKIPPFILADGPIITYNVDQSNKQPWLNKGYGQSLAPGLIWQEDHFMV
>NZ_CP012369.1|WP_053094659.1|625025_626504_+|sugar-ABC-transporter-ATP-binding-protein
MEKVLELKNIVKRYGQVPVLKGVDFDLYAGEVHAIVGQNGAGKSTLMKILAGVITDYEGTEVLKGKPVRFRSAGEAQVHGIGMVHQELSVILKLSVAENLFIGTPGSKKTFVNWWEMENKARQLLKDFGLERINVKRPLGSYLLGIQQMIEIIRTIHSSAKIIIMDEPTSALSPPEVKRLFELIGRLKQAGTSIIFISHFLDDVLDIADRITVLRDGRKITTLENKDINKAELIRLMLGSSEGISENTEIELSASEKEPVLEIKDLSCRRLFRDVAFSVGKGEVVGLFGYMGAGHMELPRVLFGLEVPEKGRVILQGKEVKIKSPGHARSLGLAYAPESRKKALCLTKPIYANITLPFLATIGRFVNNRTRELEISRQLIERTALRPPKPLLNVGNLSGGNQQKVSVSRWLPTHPIVFILSEPTRGMDVGAKEEIINLVRDLKAQGMGIIVASSEPETIFALADRILVFSKGKIVHEFKQGKVNKELLFQYA
>NZ_CP012369.1|WP_053094660.1|626531_627524_+|ABC-transporter-permease
MSVVTKKEPANLGRVLKRSLHSMAPLWTLIILFIFFSLASDTFFRIINFRNILIQVSTMAIMSTGVTFVLLTGEIDLSVADVGGLAGVIAAYATATLALPQSLSIILALVITLLLGYFNGFGTARLGIPSFMITLAMMVIAGGLSLYFTRGRVIFKIPDLLKVLGTGSIGPIPIIVIIAVIVLAVAHFVLQYTRYGRYVYMTGANREAAELSGVNTRTVIASCLAISGFTAGLSGLMNLGRLGSAQPSVPSDMLINAIAAVVLGGTSLAGGEGGIPNTIIGLLILGILRNGLDQVSTDVYLKTFITGIILVVALFLNIVASRLRHTAEDE
>NZ_CP012369.1|WP_053094661.1|627565_628831_+|S-methyl-5-thioribose-kinase
MDNFTEHIKVPEPDLSRYQPLNLETVITYVKQRPELQELFSPDEELVSSEVGDGNLNLVFRIQAKNDPARSIIIKQALPYVRLVGDSWPLSPDRAIIEGKALAIFSAICPDLTPKLYYTDYDMYLNIMEDLAPRIILHKGLIKRQHYPNFTKHIGRYLARTLGETCDLYLDPQLKKWNAAQFTNPQLCKITEDLVFTNPYIKDGNGNHFNPLIAKEVEVIQNDEELHAEMAELKDAFMSHGQALIHGDLHTGSIMVDAATTKVMDPEFAFYGPAGFDIGAVIGNLFLNYASHEGHTLDPGERREYQQYLLDLAKGVWENFVAEFQFVWEKQDPVQRPDAYRERYMLKLIQDTAGFGGAKMMRRIIGLAHVEDLESIADPEKRAVAERLGLAIGRRLVKERSHFSSISDIINVVLTSRPEVF

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Crispr_ID: NZ_CP012369_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012369_3

1667560-1670187

Unclear

Consensus_repeat	Method
GTTCAAATTCCTCTATGGTCGATGGTCAC	PILER-CR
GTTCAAATTCCTCTATGGTCGATGGTCAC	CRISPRCasFinder
GTTCAAATTCCTCTATGGTCGATGGTCAC	CRT

40 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas6

The CRISPR arrays of NZ_CP012369_3

>merge|NZ_CP012369|3|1667560-1670187|PILER-CR,CRISPRCasFinder,CRT
GTTCAAATTCCTCTATGGTCGATGATCACTCTGCCAGGTGGCCGTGGATAGTTTTGATCAACTGCCGTTCAAATTCCTCTATGGTCGATGGTCACCGTAGTTGGACTTTTATGCGCAGCAAGGCCCCCGGTAGTTCAAATTCCTCTATGGTCAATGGTCACCCAGTTTTTGCCGATGAGGACCTGGGATTGCTTCAGGTTCAAATTCCTCTATGGTCGATGGTCACAAATGGCCGTAAAACTGAAAGAGGCGGGATTAAAAGTTCAAATTCCTCTATGGTCGATGGTCACCTAATATTCCAGTGCTTTTTAACCTATTATATCTAAGTTCAAATTCCTCTATGGTCGATGGTCACGTGCAGTTACCCAAATACCGCATTACGGTGAGCCAGGTTCAAATTCCTCTATGGTCGATGGTCACAGTTTAATTCCTCTACAGGGAAGGTTACTGTTATGAGTTCAAATTCCTCTATGGTCGATGGTCACTCACCCAGGGAACGTGATGCCTGGGTGGCTCAATGTAGTTCAAATTCCTCTATGGTCGATGGTCACGGGTACCCCGGTGGCGTATGGAGCGGCTTGGGACGGTTCAAATTCCTCTATGGTCGATGGTCACACTCAACGGGTTTGAAAAGTACCTCTACATGAGCGGTTCAAATTCCTCTATGGTCGATGGTCACGAGATTTGCCGGCAGAAATATTTTATTCCCTGCCCGAAGTTCAAATTCCTCTATGGTCGATGGTCACCGAAGACGCCTGCCGCCTGGACCACCTGGACGAAAAGGTTCAAATTCCTCTATGGTCGATGGTCACAATAAAGACCTTCTCCGAATTCAAGCGATCTGGTAGGTTCAAATTCCTCTATGGTCGATGGTCACGGGTGGGAATGTTGAGAGAAGAGCTCCGAGAGCTTGGTTCAAATTCCTCTATGGTCGATGGTCACCTTTATGAATTTCGGCTCTCCGCCTACGCCCCGTAAGTTCAAATTCCTCTATGGTCGATGGTCACCGGTTGTCGCCCCGACTGGAAACCTCGGTGAGTAAGTTCAAATTCCTCTATGGTCGATGGTCACTCTTCATATTGCCTTCAGGGTCATCAGTAAAAGGAGTTCAAATTCCTCTATGGTCGATGGTCACCCCTGTCACGGAAGAAACCACCTGGCTCCGAGCCGGAGTTCAAATTCCTCTATGGTCGATGGTCACTAAAATGCTTGATGCGGATTTAATTGATGTTTATAGTTCAAATTCCTCTATGGTCGATGGTCACGCAAAAAGAAAACCGGCTTATTTGTCGCCGGTTTCTTGTTCAAATTCCTCTATGGTCGATGGTCACTCTTCGTAAATCGACTTCTTTTGCTTGATATGCCGCAGTTCAAATTCCTCTATGGTCGATGGTCACTGCCGTACTCTTCTTCACCATGCCAGACGATCCATTGTTCAAATTCCTCTATGGTCGATGGTCACCTTCGGCCCACGGCACGGAAACTTATGCTTATAAACCGTTCAAATTCCTCTATGGTCGATGGTCACCCGGAAGGGGACAAACACTTTGTGCCCCTTAACAGTTCAAATTCCTCTATGGTCGATGGTCACTGGCACACTCGCGGCACTCATTCCGCGTTATCGGGGTTCAAATTCCTCTATGGTCGATGGTCACGCTTCGACGGTTTACGGGGCTATTCCGTCATCGCTAGTTCAAATTCCTCTATGGTCGATGGTCACTGCTACGTCCAGCTTCAATATCCGCTATAAAAGAAGTTCAAATTCCTCTATGGTCGATGGTCACTTGAACACGGTCGATGCAATCCATCCATTGAAAAGCTGTTCAAATTCCTCTATGGTCGATGGTCACAAACAGGATCGGCCAGCAGCCGTTCTTCCTGGGGATGTTCAAATTCCTCTATGGTCGATGGTCACCCGGAGCAGGCTAACGGACCGGTAAAGACGACCCGTTCAAATTCCTCTATGGTCGATGGTCACCTCTTTTGCCCCATTTACAAATACAGCAATCTCCGAGTTCAAATTCCTCTATGGTCGATGGTCACCTGCCGTGGGGATGGTCAGGGTTTCGGGAGAGCGGGGTTCAAATTCCTCTATGGTCGATGGTCACCGCTACTGGCGTAGAGAATTGACTTCAGGCGGTCGAGTTCAAATTCCTCTATGGTCGATGGTCACCCTGATACCACCGCGGCCAATGACCTTCGGGTAAGTAGTTCAAATTCCTCTATGGTCGATGGTCACGGTCGCCATTGCCTGCGGGGCTGTTGATAAGCTTAAAGTTCAAATTCCTCTATGGTCGATGGTCACTTCGACGGGCAGAAAACTCAAGGGCGCAAGGGCAAAGTTCAAATTCCTCTATGGTCGATGGTCACGGGTGCTAGACCCGCAGGAGGGGACGGTGGAGTTTGTTCAAATTCCTCTATGGTCGATGGTCACACGTAGAGCATAACGTCGAGACTTTGAAAATCTCCCGTTCAAATTCCTCTATGGTCGATGGTCACGGCTGGCCGAAAAGGAAGGAATAATTGTAGATTATGTTCAAATTCCTCTATGGTCGATGGTCACAATCTGCTGTTGATTATAGTACTACTTTTACCGCAGGTTCAAATTCCTCTATGGTCGATGGTCAC

>NZ_CP012369|3|2|1667560-1670187|PILER-CR
GTTCAAATTCCTCTATGGTCGATGATCAC	TCTGCCAGGTGGCCGTGGATAGTTTTGATCAACTGCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGTAGTTGGACTTTTATGCGCAGCAAGGCCCCCGGTA
GTTCAAATTCCTCTATGGTCAATGGTCAC	CCAGTTTTTGCCGATGAGGACCTGGGATTGCTTCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AAATGGCCGTAAAACTGAAAGAGGCGGGATTAAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTAATATTCCAGTGCTTTTTAACCTATTATATCTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GTGCAGTTACCCAAATACCGCATTACGGTGAGCCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AGTTTAATTCCTCTACAGGGAAGGTTACTGTTATGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCACCCAGGGAACGTGATGCCTGGGTGGCTCAATGTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTACCCCGGTGGCGTATGGAGCGGCTTGGGACG
GTTCAAATTCCTCTATGGTCGATGGTCAC	ACTCAACGGGTTTGAAAAGTACCTCTACATGAGCG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GAGATTTGCCGGCAGAAATATTTTATTCCCTGCCCGAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGAAGACGCCTGCCGCCTGGACCACCTGGACGAAAAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AATAAAGACCTTCTCCGAATTCAAGCGATCTGGTAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTGGGAATGTTGAGAGAAGAGCTCCGAGAGCTTG
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTTTATGAATTTCGGCTCTCCGCCTACGCCCCGTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGGTTGTCGCCCCGACTGGAAACCTCGGTGAGTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCTTCATATTGCCTTCAGGGTCATCAGTAAAAGGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCCTGTCACGGAAGAAACCACCTGGCTCCGAGCCGGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TAAAATGCTTGATGCGGATTTAATTGATGTTTATA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GCAAAAAGAAAACCGGCTTATTTGTCGCCGGTTTCTT
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCTTCGTAAATCGACTTCTTTTGCTTGATATGCCGCA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGCCGTACTCTTCTTCACCATGCCAGACGATCCATT
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTTCGGCCCACGGCACGGAAACTTATGCTTATAAACC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCGGAAGGGGACAAACACTTTGTGCCCCTTAACA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGGCACACTCGCGGCACTCATTCCGCGTTATCGGG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GCTTCGACGGTTTACGGGGCTATTCCGTCATCGCTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGCTACGTCCAGCTTCAATATCCGCTATAAAAGAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TTGAACACGGTCGATGCAATCCATCCATTGAAAAGCT
GTTCAAATTCCTCTATGGTCGATGGTCAC	AAACAGGATCGGCCAGCAGCCGTTCTTCCTGGGGAT
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCGGAGCAGGCTAACGGACCGGTAAAGACGACCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTCTTTTGCCCCATTTACAAATACAGCAATCTCCGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTGCCGTGGGGATGGTCAGGGTTTCGGGAGAGCGGG
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGCTACTGGCGTAGAGAATTGACTTCAGGCGGTCGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCTGATACCACCGCGGCCAATGACCTTCGGGTAAGTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGTCGCCATTGCCTGCGGGGCTGTTGATAAGCTTAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TTCGACGGGCAGAAAACTCAAGGGCGCAAGGGCAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTGCTAGACCCGCAGGAGGGGACGGTGGAGTTT
GTTCAAATTCCTCTATGGTCGATGGTCAC	ACGTAGAGCATAACGTCGAGACTTTGAAAATCTCCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGCTGGCCGAAAAGGAAGGAATAATTGTAGATTAT
GTTCAAATTCCTCTATGGTCGATGGTCAC	AATCTGCTGTTGATTATAGTACTACTTTTACCGCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC

>NZ_CP012369|3|3|1667560-1670187|CRISPRCasFinder
GTTCAAATTCCTCTATGGTCGATGATCAC	TCTGCCAGGTGGCCGTGGATAGTTTTGATCAACTGCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGTAGTTGGACTTTTATGCGCAGCAAGGCCCCCGGTA
GTTCAAATTCCTCTATGGTCAATGGTCAC	CCAGTTTTTGCCGATGAGGACCTGGGATTGCTTCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AAATGGCCGTAAAACTGAAAGAGGCGGGATTAAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTAATATTCCAGTGCTTTTTAACCTATTATATCTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GTGCAGTTACCCAAATACCGCATTACGGTGAGCCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AGTTTAATTCCTCTACAGGGAAGGTTACTGTTATGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCACCCAGGGAACGTGATGCCTGGGTGGCTCAATGTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTACCCCGGTGGCGTATGGAGCGGCTTGGGACG
GTTCAAATTCCTCTATGGTCGATGGTCAC	ACTCAACGGGTTTGAAAAGTACCTCTACATGAGCG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GAGATTTGCCGGCAGAAATATTTTATTCCCTGCCCGAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGAAGACGCCTGCCGCCTGGACCACCTGGACGAAAAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AATAAAGACCTTCTCCGAATTCAAGCGATCTGGTAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTGGGAATGTTGAGAGAAGAGCTCCGAGAGCTTG
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTTTATGAATTTCGGCTCTCCGCCTACGCCCCGTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGGTTGTCGCCCCGACTGGAAACCTCGGTGAGTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCTTCATATTGCCTTCAGGGTCATCAGTAAAAGGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCCTGTCACGGAAGAAACCACCTGGCTCCGAGCCGGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TAAAATGCTTGATGCGGATTTAATTGATGTTTATA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GCAAAAAGAAAACCGGCTTATTTGTCGCCGGTTTCTT
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCTTCGTAAATCGACTTCTTTTGCTTGATATGCCGCA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGCCGTACTCTTCTTCACCATGCCAGACGATCCATT
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTTCGGCCCACGGCACGGAAACTTATGCTTATAAACC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCGGAAGGGGACAAACACTTTGTGCCCCTTAACA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGGCACACTCGCGGCACTCATTCCGCGTTATCGGG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GCTTCGACGGTTTACGGGGCTATTCCGTCATCGCTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGCTACGTCCAGCTTCAATATCCGCTATAAAAGAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TTGAACACGGTCGATGCAATCCATCCATTGAAAAGCT
GTTCAAATTCCTCTATGGTCGATGGTCAC	AAACAGGATCGGCCAGCAGCCGTTCTTCCTGGGGAT
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCGGAGCAGGCTAACGGACCGGTAAAGACGACCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTCTTTTGCCCCATTTACAAATACAGCAATCTCCGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTGCCGTGGGGATGGTCAGGGTTTCGGGAGAGCGGG
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGCTACTGGCGTAGAGAATTGACTTCAGGCGGTCGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCTGATACCACCGCGGCCAATGACCTTCGGGTAAGTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGTCGCCATTGCCTGCGGGGCTGTTGATAAGCTTAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TTCGACGGGCAGAAAACTCAAGGGCGCAAGGGCAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTGCTAGACCCGCAGGAGGGGACGGTGGAGTTT
GTTCAAATTCCTCTATGGTCGATGGTCAC	ACGTAGAGCATAACGTCGAGACTTTGAAAATCTCCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGCTGGCCGAAAAGGAAGGAATAATTGTAGATTAT
GTTCAAATTCCTCTATGGTCGATGGTCAC	AATCTGCTGTTGATTATAGTACTACTTTTACCGCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC

>NZ_CP012369|3|2|1667560-1670187|CRT
GTTCAAATTCCTCTATGGTCGATGATCAC	TCTGCCAGGTGGCCGTGGATAGTTTTGATCAACTGCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGTAGTTGGACTTTTATGCGCAGCAAGGCCCCCGGTA
GTTCAAATTCCTCTATGGTCAATGGTCAC	CCAGTTTTTGCCGATGAGGACCTGGGATTGCTTCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AAATGGCCGTAAAACTGAAAGAGGCGGGATTAAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTAATATTCCAGTGCTTTTTAACCTATTATATCTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GTGCAGTTACCCAAATACCGCATTACGGTGAGCCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AGTTTAATTCCTCTACAGGGAAGGTTACTGTTATGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCACCCAGGGAACGTGATGCCTGGGTGGCTCAATGTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTACCCCGGTGGCGTATGGAGCGGCTTGGGACG
GTTCAAATTCCTCTATGGTCGATGGTCAC	ACTCAACGGGTTTGAAAAGTACCTCTACATGAGCG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GAGATTTGCCGGCAGAAATATTTTATTCCCTGCCCGAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGAAGACGCCTGCCGCCTGGACCACCTGGACGAAAAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	AATAAAGACCTTCTCCGAATTCAAGCGATCTGGTAG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTGGGAATGTTGAGAGAAGAGCTCCGAGAGCTTG
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTTTATGAATTTCGGCTCTCCGCCTACGCCCCGTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGGTTGTCGCCCCGACTGGAAACCTCGGTGAGTAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCTTCATATTGCCTTCAGGGTCATCAGTAAAAGGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCCTGTCACGGAAGAAACCACCTGGCTCCGAGCCGGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TAAAATGCTTGATGCGGATTTAATTGATGTTTATA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GCAAAAAGAAAACCGGCTTATTTGTCGCCGGTTTCTT
GTTCAAATTCCTCTATGGTCGATGGTCAC	TCTTCGTAAATCGACTTCTTTTGCTTGATATGCCGCA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGCCGTACTCTTCTTCACCATGCCAGACGATCCATT
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTTCGGCCCACGGCACGGAAACTTATGCTTATAAACC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCGGAAGGGGACAAACACTTTGTGCCCCTTAACA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGGCACACTCGCGGCACTCATTCCGCGTTATCGGG
GTTCAAATTCCTCTATGGTCGATGGTCAC	GCTTCGACGGTTTACGGGGCTATTCCGTCATCGCTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TGCTACGTCCAGCTTCAATATCCGCTATAAAAGAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TTGAACACGGTCGATGCAATCCATCCATTGAAAAGCT
GTTCAAATTCCTCTATGGTCGATGGTCAC	AAACAGGATCGGCCAGCAGCCGTTCTTCCTGGGGAT
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCGGAGCAGGCTAACGGACCGGTAAAGACGACCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTCTTTTGCCCCATTTACAAATACAGCAATCTCCGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CTGCCGTGGGGATGGTCAGGGTTTCGGGAGAGCGGG
GTTCAAATTCCTCTATGGTCGATGGTCAC	CGCTACTGGCGTAGAGAATTGACTTCAGGCGGTCGA
GTTCAAATTCCTCTATGGTCGATGGTCAC	CCTGATACCACCGCGGCCAATGACCTTCGGGTAAGTA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGTCGCCATTGCCTGCGGGGCTGTTGATAAGCTTAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	TTCGACGGGCAGAAAACTCAAGGGCGCAAGGGCAAA
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGGTGCTAGACCCGCAGGAGGGGACGGTGGAGTTT
GTTCAAATTCCTCTATGGTCGATGGTCAC	ACGTAGAGCATAACGTCGAGACTTTGAAAATCTCCC
GTTCAAATTCCTCTATGGTCGATGGTCAC	GGCTGGCCGAAAAGGAAGGAATAATTGTAGATTAT
GTTCAAATTCCTCTATGGTCGATGGTCAC	AATCTGCTGTTGATTATAGTACTACTTTTACCGCAG
GTTCAAATTCCTCTATGGTCGATGGTCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012369.1\|WP_011393230.1\|1672057_1674811_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP012369.1\|WP_158499110.1\|1666110_1666299_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012369.1\|WP_053094904.1\|1658590_1659685_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|374853
NZ_CP012369.1\|WP_011393234.1\|1678267_1678948_-\|hypothetical-protein	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NZ_CP012369.1\|WP_011393233.1\|1676785_1678264_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	unknown	unknown	gnl\|CDD\|162595
NZ_CP012369.1\|WP_011393224.1\|1660792_1662073_-\|B12-lower-ligand-biosynthesis-ThiC-like-protein-BzaB	unknown	unknown	gnl\|CDD\|237359
NZ_CP012369.1\|WP_148844662.1\|1663941_1664121_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012369.1\|WP_011393221.1\|1657641_1658115_-\|NAD(P)H-dependent-oxidoreductase-subunit-E	unknown	unknown	gnl\|CDD\|376507
NZ_CP012369.1\|WP_011393235.1\|1679246_1680650_-\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydG	unknown	unknown	gnl\|CDD\|236590
NZ_CP012369.1\|WP_011393228.1\|1670552_1671518_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP012369.1\|WP_162490149.1\|1667132_1667513_-\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	unknown	unknown	gnl\|CDD\|238546
NZ_CP012369.1\|WP_162490071.1\|1675694_1676759_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	pfam01905_cas7_CAS-I	gnl\|CDD\|376656
NZ_CP012369.1\|WP_011393226.1\|1664835_1666044_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_CP012369.1\|WP_011393236.1\|1680764_1681817_-\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE	unknown	unknown	gnl\|CDD\|180835
NZ_CP012369.1\|WP_011393229.1\|1671534_1672068_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP012369.1\|WP_011393225.1\|1662085_1663384_-\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|237359
NZ_CP012369.1\|WP_053094907.1\|1674810_1675695_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860
NZ_CP012369.1\|WP_080997190.1\|1655746_1657606_-\|NADH-quinone-oxidoreductase-subunit-NuoF	unknown	unknown	gnl\|CDD\|224806
NZ_CP012369.1\|WP_162490148.1\|1659681_1660767_-\|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|376752
NZ_CP012369.1\|WP_053095251.1\|1670268_1670550_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856

Protein	Function_ID	Function_description	E-value
NZ_CP012369.1\|WP_011393230.1\|1672057_1674811_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.25188e-53
NZ_CP012369.1\|WP_053094907.1\|1674810_1675695_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	5.9139e-21
NZ_CP012369.1\|WP_053094904.1\|1658590_1659685_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|374853	pfam16864, dimerization2, dimerization domain. This domain, found in methyltransferases, functions as a dimerization domain.	3.81667e-27
NZ_CP012369.1\|WP_011393234.1\|1678267_1678948_-\|hypothetical-protein	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	2.02445e-11
NZ_CP012369.1\|WP_011393233.1\|1676785_1678264_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|162595	TIGR01908, Uncharacterized_protein_aq_372, CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This (revised) model describes a conserved region from an otherwise highly divergent protein found in the Tneap subtype of CRISPR/Cas regions. This Cys-rich region features two motifs of CXXC.	2.96057e-06
NZ_CP012369.1\|WP_011393224.1\|1660792_1662073_-\|B12-lower-ligand-biosynthesis-ThiC-like-protein-BzaB	gnl\|CDD\|237359	PRK13352, PRK13352, phosphomethylpyrimidine synthase ThiC.	0
NZ_CP012369.1\|WP_011393221.1\|1657641_1658115_-\|NAD(P)H-dependent-oxidoreductase-subunit-E	gnl\|CDD\|376507	pfam01257, 2Fe-2S_thioredx, Thioredoxin-like [2Fe-2S] ferredoxin.	3.99752e-69
NZ_CP012369.1\|WP_011393235.1\|1679246_1680650_-\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydG	gnl\|CDD\|236590	PRK09613, thiH, thiamine biosynthesis protein ThiH; Reviewed.	0
NZ_CP012369.1\|WP_011393228.1\|1670552_1671518_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	0
NZ_CP012369.1\|WP_162490149.1\|1667132_1667513_-\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	gnl\|CDD\|238546	cd01126, TraG_VirD4, The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer to plant cells and is required for virulence.	4.24451e-13
NZ_CP012369.1\|WP_162490071.1\|1675694_1676759_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|376656	pfam01905, DevR, CRISPR-associated negative auto-regulator DevR/Csa2. This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly interspaced short palindromic repeats, DNA repeats found in nearly half of all bacterial and archaeal genomes. These DNA repeat regions have a remarkably regular structure: unique sequences of constant size, called spacers, sit between each pair of repeats. It has been shown that the CRISPRs are virus-derived sequences acquired by the host to enable them to resist viral infection. The Cas proteins from the host use the CRISPRs to mediate an antiviral response. After transcription of the CRISPR, a complex of Cas proteins termed Cascade cleaves a CRISPR RNA precursor in each repeat and retains the cleavage products containing the virus-derived sequence. Assisted by the helicase Cas3, these mature CRISPR RNAs then serve as small guide RNAs that enable Cascade to interfere with virus proliferation. Cas5 contains an endonuclease motif, whose inactivation leads to loss of resistance, even in the presence of phage-derived spacers. This family used to be known as DUF73. DevR appears to be negative auto-regulator within the system.	1.75953e-50
NZ_CP012369.1\|WP_011393226.1\|1664835_1666044_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	8.02743e-32
NZ_CP012369.1\|WP_011393236.1\|1680764_1681817_-\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE	gnl\|CDD\|180835	PRK07094, PRK07094, biotin synthase; Provisional.	0
NZ_CP012369.1\|WP_162490148.1\|1659681_1660767_-\|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase	gnl\|CDD\|376752	pfam02277, DBI_PRT, Phosphoribosyltransferase. This family of proteins represent the nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) enzymes involved in dimethylbenzimidazole synthesis. This function is essential to de novo cobalamin (vitamin B12) production in bacteria. Nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase (CobT) from Salmonella enterica plays a central role in the synthesis of alpha-ribazole-5'-phosphate, an intermediate for the lower ligand of cobalamin.	6.73691e-179
NZ_CP012369.1\|WP_011393225.1\|1662085_1663384_-\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|237359	PRK13352, PRK13352, phosphomethylpyrimidine synthase ThiC.	0
NZ_CP012369.1\|WP_080997190.1\|1655746_1657606_-\|NADH-quinone-oxidoreductase-subunit-NuoF	gnl\|CDD\|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	0
NZ_CP012369.1\|WP_011393229.1\|1671534_1672068_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.217e-66
NZ_CP012369.1\|WP_053095251.1\|1670268_1670550_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.55686e-25

>NZ_CP012369.1|WP_162490149.1|1667132_1667513_-|type-IV-secretory-system-conjugative-DNA-transfer-family-protein
MGLGTRLQVFQQEMVRRITGDSDIDLTLPGKGKCAYFIITPDTHGAFDFLASLLFTFLFVRLVEVADTSPNGRLPVQVSFLLDEFANIVSIPEFEKKIATVQSLRLKTNLTMAEIRITMILRTRNL
>NZ_CP012369.1|WP_158499110.1|1666110_1666299_-|hypothetical-protein
MDNFLRRLAARFQDRVANVEFFCGECCKKDKGGKLTLVGRDFIELIEVDDLKLKVSLFPVAI
>NZ_CP012369.1|WP_011393226.1|1664835_1666044_+|IS1634-family-transposase
MPVAMDNMRFFRAGPAALISRLCDVLKIAEIIDAVVDWDPAQCHLSPGNRVKALIINLLVDREALYHVERFYENQDLEVLFGAEQQVRPEDFNDDALGRALDKLFTSGQLKKLFSSIALTAAATHNVSIAGIHVDTTSISVQGAYDGEGDLDITFGFSKDHRPDLKQFLIGLTVNRDGLPILAQSLDGNSSDKSWYPQVIEELVQTFKPEKLKEVIFVADCALVTKDNLALLVQEEGNKPALQFISLLPENFGLNKEIKAEAFRTGTWQEIGKLSPKKDAACYKSQSFVREIDGRDYRLIVVHSTTLDKRKENSLLKKWAKQREVLEKAAKDLSRRPFACKADARKAIELFLREYRHQPFILKGTVDEEIVSNYYQGPEVIRALELAGFGKEIYLFPPRGGG
>NZ_CP012369.1|WP_148844662.1|1663941_1664121_-|hypothetical-protein
MAEGKLVLVPLKEKPFVRLYGALKGETNLVRSLQEEHARETEKENRRVELRVGIGDHRP
>NZ_CP012369.1|WP_011393225.1|1662085_1663384_-|phosphomethylpyrimidine-synthase-ThiC
MNLIESARAGLITPEMEQVAVQEGVTPEFVRQGVADGTIVILRNARRQNVTPVGVGKGLRTKVSASVGLYGETGGIDVEVAKIKAAVEAGTDAIMDLSVSGDIEAMLAETLAVSPKPVGTLPLYQAMAEAGRKYGSSVNMRDEDLFDVIERHAAAGVDFLALHCGTTMNIVERARNEGRIDPLVSYGGSHLIGWMLANRRENPLYEHFDRVLAIARKYDVTISFADGMRPGCLADSLDGPQVEELVVLGELVRRAREAGVQVMVKGPGHVPLQQLKATVVLEKSLCHGAPYFVFGPLVTDIAIGYDHINAAIGGALSAWAGAEFLCYVTAAEHVGIPDIDQVREGVIAARIAAHAADLANGLTCAREWDRELSRARKELDWKRQIALAIDPERAGRLREERSDAAAAGCAMCGKYCAMEIVSRYLGTARHTC
>NZ_CP012369.1|WP_011393224.1|1660792_1662073_-|B12-lower-ligand-biosynthesis-ThiC-like-protein-BzaB
MSQVLDARAGKITPEMEKVAADEKVDVEFVRAGVAEGTIVIPRNTNRKVLKPCGIGRGLRIKVNALIGTSSDRDDRQMEMRKIAAAEAAGCDSFMDLSTGGDIDEMRRLTLAHARVPVGSVPIYQAAIEAIEKRGSIVAMTPDDMFAAVEKQARDGIDFMAIHSALNFEILERLQASGRVTDIVSRGGAFLTGWMLHNQKENPLYEQFDRLLEILLKYDVTLSLGDAIRPGSTADSLDGAQLQGMIVAGELVRRAREAGVQVMVEGPGHVPLNHVETTMKLQKSLCGGAPYFILGTLATDVAPGYDHITAAIGGALAGTVGADFICYVTPAEHLGLPTEQDVKEGVIAARIAAHAADLARGNRQAWERDLQMARARVALDVEKQISLAIDQEKARSLLDGTGEDGVCAACGTNCAALVAARYFGMN
>NZ_CP012369.1|WP_162490148.1|1659681_1660767_-|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase
MGLKLEETVKGIMPVNDAWRRKAREHLNNLAIPVGSLGRLLDIAEQLAAIKESLKPSTGSKVVVTMAGDHGVVEEGVSTCPQRVTLQMVYNFVAGGAGINALAGAAGARVVVVDMGVAGDLKDLVEQGKILSRKVDYGTRNMTRGPAMTRQQAVQALETGINIAGDLVNEGVELLGTGDMGIGNTTPSSAILAALSGLPVREVTGRGTGIDDETLARKVQVIERALALNRPDPGDPVDVLAKVGGFEIGGIAGLILGAAYYRVPVVVDGFISTAGALLAKQLAPRAVDYMIAAHRSMEYGHRYMLKELGLRPLLDLDMRLGEGTGAALAMCIVEGAARVIGEMLTFEDAGVARNKSREYAV
>NZ_CP012369.1|WP_053094904.1|1658590_1659685_-|methyltransferase-domain-containing-protein
MKPGFLKYDPQAPCPQYLEDLATGYWFSEVLFTAVEAGLFTLLAGGGMSAAEIAEALGFSIHGTERFLGALCALGLIGRDGDVFFNTRLSETYLVRGREHYQGDSILWRKHLASSWRGLKECLEAGGRVSYPPPGESRECMGQRVGRYIRAMDNVARYKVQEILPIFEGVFDTGRVLDVGSGSGAVAAGFLEQYPGLAATLVDIPEVLELAKMLMEERGLGGRVTCHPANILEPGALPQGPFDLVILSNILHIYTEKEGALLLSRAAGCLGAAGFLLVHDFFPEHRPEKAALMDLNMLINTYNGKVLSSRWVRERLEARGLCSTELVLLRSDTALVIAARDAGALEKLKLAPGVIRPDRSLLIS
>NZ_CP012369.1|WP_011393221.1|1657641_1658115_-|NAD(P)H-dependent-oxidoreductase-subunit-E
METCQCEAKWEELEKIIDAHRGQPSALIEVLHQSQELVGYLPRNVQVAIADGLGLSLSQVYSVVSFYNHFTTKPKGKYQVSVCMGTACFVKGAPAILERLEQELGTKVGDTTADGRFTINQVRCLGCCALGPVMTVNQKAHGRLTPDTALEILKEYQ
>NZ_CP012369.1|WP_080997190.1|1655746_1657606_-|NADH-quinone-oxidoreductase-subunit-NuoF
MIKSMEELQKFKESQLEAMQSQEAGAKAKIVVGMGTCGIAAGAREVMNAILDEVAKRQLTGVTVSQTSCIGLCAQEPLVDVILPGQPKVTYGKVDAAKAREIVGRHVVDGHIVTEWVVNRQGDAVRPYTELPFFKHQVRIALRNCGLIDPESIGEYIAHDGYQALSKVLTTMKPYEVIETIKKSGLRGRGGGGFPTGLKWEFAYRSPGPVKYFVCNADEGDPGAFMDRSILEGDPHAVLEGMAIGAYAIGASQGYIYVRAEYPVAVQRLKLAISQAREQGLLGKNLFNSGFDFDIDIRLGAGAFVCGEETALLASIEGRRGEPRPRPPFPAVSGLWGKPTVINNVETLANIPTIIRQGWEWFAGIGTEKSKGTKVFALAGKINNNGLVEIPMGTSLRQVIYEIGGGIPGGKKFKVAQTGGPSGGCIPAEHLDAPIDYENLTALGTIMGSGGLIIMDEDTCMVDVAKFFMDFVKDESCGKCTPCRIGTTRMLEILNRITRGQGEEKDLDLLVELARQIKDTALCGLGQTAPNPVLSTITYFRDEYLAHIRDHRCPAHVCQELLSYVIDAGKCTGCGACSRVCPVGAISGGKKEAHQIDPAACIKCGSCYEKCRFGAITRE
>NZ_CP012369.1|WP_053095251.1|1670268_1670550_-|CRISPR-associated-endonuclease-Cas2
MRVILIYDINTEDNDGKRRLVKIMKTSRKYLSHVQKSVFEGDITEGQISLLKKEIMAIVNMKKDFVIIYSLRDGVKLNREILTDTPDPTDNFL
>NZ_CP012369.1|WP_011393228.1|1670552_1671518_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRTYYIFSSGRLRRMDNTLALELETERRVVPVEDIDHIYCFSELDLNTRLLDFLAQKQICLHFFNYYGHYSGSFIPRESQLSGFLLVRQVEHYLDQAKRLELARTFVEGALHNIRRNLEKREYDDICSKLDEIREGIGKTASIEELMSLEAHARKAYYDTWEEITGWEFGSRSKRPPANALNALISFGNAMMYTVVLKEIYRTALNPTISYLHEPSERRYSLALDVAEIFKPVFVDRLIFRLINLNMLKETHFDTNVNFVYLTEGGRKVFVKEFEETLEKTILHRKLKRNIRYKSLVRLDLYKLIKHLLGEEKYSPMKVWW
>NZ_CP012369.1|WP_011393229.1|1671534_1672068_-|CRISPR-associated-protein-Cas4
MNSDQVTELRKAHITGTMVAYYFICHRKLWLFAKGLNLENISGNADVIKGRILHETRFNRQNNKEVAFDTVKIDFLHYNGQVYVHEVKKSKKFEEAHTWQLKYYIYMLQEKGVNCSAGVIHYPSSMRREEVNFTPGDRELLMKALAGIQAVLSKPLPEKKAGRKMCSRCAYFDFCYI
>NZ_CP012369.1|WP_011393230.1|1672057_1674811_-|CRISPR-associated-helicase/endonuclease-Cas3
MADFWAKSNGISLSKHTGDVLAATGVLQKKLGNKVPGDWWLGLKYAALLHDSGKVDPAFQERIKKQGQKAGDVPADEPKYKDIPHSILSLFFVRPENFTFSQPYLAYAVISAIVFHHWRESFPDYFLGSQEYLIRKKAGELEERAALWNRLSRDLVAELTILAEKYELDPAVMGLNTTLTEYLRYNTLGSAGLLIPPYTLVYLPEQIRAKAARGDEKDRARVFIAGNLMRADHFASMVEESNTGLQIDAIESGRVFTTGEIERTLKEKFNTPDYWQKQFFQNHKEAKGDNLVLVAPTGFGKTEFAFLWGAEKKNFILLPMRAAVNKIWERTRDMVESLGEKGDDQVALLHSDAALETFSRYQQQGDLESESNTRKAMELARHLARTYIIATADQVAPAALRYPGYERIFAALMNGALVIDEVQAYDPRAAAIITHLVQQNAYLGGNNLIMTATLPPFISRELVKRLGLADHQVIRLIDEPEFEGVAASCRHRLGFNVHAGDYASAVTAIIRAAQQGKKVLVVMNTVRAACEIYDKIMAVLQQEQLAIETLLLHSRFILKQKEELEKAVVEKYMPNRPDRDAGPCIVVATQIVEASLDIDADVLFTEPSPADSLIQRMGRVFRRFARLTGNNAPPEANVIIIINGGDQPLNRRRRSDQEEKTAGDVQLASGLKTVYNRDLTALSLVILLMALKGEAGLSPGSSLAEELKRKPWVDCFKKSKGKGNSGNTNRRLVEVIKSITGQTLLLTEKEKMDWVELTYGILDELRRIDNYPLQLEDYIQKYEETLAILDHGYCSDRKRDAERLFRDINAITGVPIEKAGEFYDSIRTWLSGKNAGSLNFLELALAILPRFTVNCPFLATSNGERVRDLDFEAMLPPELDIKSITKIRSRLERWLKGIYILDLPYDQVKGLEVQNEQ
>NZ_CP012369.1|WP_053094907.1|1674810_1675695_-|type-I-B-CRISPR-associated-protein-Cas5
MGATAVRALRVLKLGFTAASAHFRVTSSNNPRKTYPLPPYSTVIGLLANILGDRAKIEAMLAGGLALGVLAQHNYITKEYTWLRNMSPSAHKGRFYSYDNRRWQETPEHPGGQSPVVVEVLNDVKVYVYLYHPNEQVTGFLMENACLPERWLSHLHLGRAEDWAMITEATIMEICPSNEGGCLQNSSNFYQWMPAPAAAFGLNELLDAAEYTSFYQKMQGNAVLVTSLYRLVEVPYQFGKKGLIRNFAHVPARLCCGQVPFLDNFRLPSLLVDRELKTPVYMAAINQESGKEGR
>NZ_CP012369.1|WP_162490071.1|1675694_1676759_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MMEVKGITATVIFESSAVNRDEKLGGNITSIKKLSRYDGTYSFMSRAFIRHHMFATFMRLYGWEEAPVTRDDAVIQFRFPDANIVAYPETDIFGFMNTSPFSVTRKAPLGITKAISLEPWQADMAFYANHDLVRRANAQGDNANPNPFQKEEHYSYYRLSFTLDLCRLGYQDIYVAGGDGLTAFKNWLKKYPEAPAGELVELRSLRSFPENMKWHYIPDADNKPRGFVGITDNGNNSRIIFVVSKGEFRERLRQFLTVVKNGLVIHSSTEDYGMVPVFIVLGTLKVPVPVFNSDVRLKNGKVDAGPLNRALNNDYLLEAWYESSLPFDGKLACGEGTRSFKPWAGVDRVLEAIN
>NZ_CP012369.1|WP_011393233.1|1676785_1678264_-|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MQDIEIYPASWYYNACVQGFLEVLAYGLGEKGEEIVAGKILQEDGRAVIPGDLMDAAFKPRGTPFPDGYVFREVPAELPALKRIGWWWVEKSYKEGFIPSKDKKAKRNNPTNAEKIDMVFGRLFHFKGGYYPNLANLGHLKSTASKAEFLNIWFDLNNIHTLRTPICSFCGRKTELEINSSTYNTFFTRTVSIYLGNSYEEFPNLFWDGNPNLIMCKQCRSYFLCFHLISKFFINSDSLLVNWHLNRLLAGRTGKGGHKTLLSAMQYDRQLRRALGSWGLQNMELLVFEQDSVEYYPISARLARLLLIPRVSSLIGQIANDRIWEIILRERFDYLPTVIYKSLRALLKGGNNEKDPEVVYKDVTNVAPVTNLIHLYYMIRQQLARNEGGTSMGYLNLKAIQAAAAEAPVDLNSNLDKNLVYRLLELTRLNKKTEVYHLLLRLYLTSGDNKQFPASLASLFATSDSELFKTGIYTFIAGLKANENDEPQGEND
>NZ_CP012369.1|WP_011393234.1|1678267_1678948_-|hypothetical-protein
MVLPLDFRRHFISLIKTLAGTSALAARFTLEKPGYSPYVFSVEFNKIIDIDTRQREITARPPILVTISTGLFDVMTTFSNGAIAMKGRETVLGLYLKDIYLLPLKQIQTGEQEFRIAGHAVFRGVRHYVDGSDVRELEEAINTHLYKRYSFLIQQYHLDYHSRVSPVKVLGPPSYHKGVCFHYGGQLTTLQGRIHLKSTPETLQFLYDFGLGIRTGQGFGLLEVGD
>NZ_CP012369.1|WP_011393235.1|1679246_1680650_-|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydG
MQHGYRADFINHEEIEGYLEEAKRATRDVAVRIIEKAREAKGLEPYEVAVLLQNDDADVRRRMFTAAREIKEKIYGQRIVLFAPLYFSDYCINNCRYCGYRRENKFERRRLEPEELEREVRILESLGHKRLALEAGEDPVHCPLEYTLDVINRIYRITEANGSIRRVNVNIAATTVDAYRQLKAAGIGTYVLFQETYHRPTYAYMHPGGPKADYDWHTTAMDRAMEGGIDDVGLGVLFGLYDYKFEVMGLLYHARHLEETFGVGPHTISVPRLRPAYNITLEKFPYLVDDEDFKKLVAIIRLAVPYTGMIISTRETAELRAELLELGVSQISAGSCTGVGGYGRHYADQEDDIPQFEIGDHRHPDEVIGDLCRRGYLPSYCTACYRRGRTGDRFMSLAKTGEIQHCCQPNAILTFKEYLLDYARPATREVGETTIREHLARIPSPAIRAETERRLERIAAGERDLYF
>NZ_CP012369.1|WP_011393236.1|1680764_1681817_-|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE
MRPEFAASWQRAAAGEELDREDIVNLLAATPGEEEEALYRLADGVRARMAGDEVHLRGVIEFSNYCRRRCCYCGLRADNARLHRYRLMPEDIVAVARQGVELGYGTIVLQSGEDPWYTAPVLAGIVREIKEMGVAVTLCVGERSREEYALWREAGADRYLLKHETANEELYARLHPGMSWQERLQCLQWLRELGYQVGSGNIIGLPGQTLADLADDLLLLRQLDVEMAGLGPFIPHPATPLAGEPAGSLELTYRVVATARLVIPFAHLPATTAVGTLAPNGRQKALQRGANVIMPNLTPTRYRADYQIYPNKICINEGPEDCRYCLEGMVRALGRRLGRGPGHTLKPIPA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012369_3	3.19\|1668761\|35\|NZ_CP012369\|PILER-CR,CRISPRCasFinder,CRT	1668761-1668795	35	NC_015938	Salmonella phage 7-11, complete genome	16459-16493	8	0.771
NZ_CP012369_3	3.27\|1669280\|35\|NZ_CP012369\|PILER-CR,CRISPRCasFinder,CRT	1669280-1669314	35	NZ_LR134399	Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence	353801-353835	8	0.771
NZ_CP012369_1	1.17\|421380\|35\|NZ_CP012369\|PILER-CR,CRISPRCasFinder,CRT	421380-421414	35	NZ_CP016024	Ralstonia insidiosa strain ATCC 49129 plasmid pRI-1, complete sequence	69648-69682	10	0.714

1. spacer 3.19|1668761|35|NZ_CP012369|PILER-CR,CRISPRCasFinder,CRT matches to NC_015938 (Salmonella phage 7-11, complete genome) position: , mismatch: 8, identity: 0.771

taaaatgcttgatgcggatttaattgatgtttata	CRISPR spacer
tggacatattgatgcggctttaattgatgttaata	Protospacer
*..*    ********* ************* ***

2. spacer 3.27|1669280|35|NZ_CP012369|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134399 (Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.771

tgctacgtccagcttcaatatccgctataaaagaa	CRISPR spacer
agtcaaagccagcttcaatatccgctatataagat	Protospacer
 *..* . ********************* ****

3. spacer 1.17|421380|35|NZ_CP012369|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016024 (Ralstonia insidiosa strain ATCC 49129 plasmid pRI-1, complete sequence) position: , mismatch: 10, identity: 0.714

tttcggcttcggggccttatattccttgccatcca	CRISPR spacer
cgccaacttcgtggcctgatattccttgccatttg	Protospacer
. .*..***** ***** **************...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

304775 : 330767

Bacillus_phage(33.33%)

transposase,integrase

attL 326426:326440|attR 333434:333448

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011392192.1\|304775_306263_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	5.2e-27	29.1
WP_011391929.1\|306529_307699_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_165442559.1\|307718_307892_+	hypothetical protein	NA	NA	NA	NA
WP_011391930.1\|307936_308560_+	cobalamin B12-binding domain-containing protein	NA	NA	NA	NA
WP_011391931.1\|309288_310407_+	ATP-binding protein	NA	NA	NA	NA
WP_011391837.1\|310458_310800_+\|transposase	transposase	NA	NA	NA	NA
WP_080997160.1\|310955_311318_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_080997161.1\|311296_311728_+\|transposase	transposase	NA	NA	NA	NA
WP_011391932.1\|312013_312343_+	STAS domain-containing protein	NA	NA	NA	NA
WP_053094589.1\|312343_313045_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_011391934.1\|313051_313381_+	STAS domain-containing protein	NA	NA	NA	NA
WP_162490017.1\|313460_315221_+	DUF342 domain-containing protein	NA	NA	NA	NA
WP_011391936.1\|315468_316119_+	TMEM165/GDT1 family protein	NA	NA	NA	NA
WP_162490018.1\|316596_316824_+	hypothetical protein	NA	NA	NA	NA
WP_011391939.1\|318483_318774_+	hypothetical protein	NA	NA	NA	NA
WP_011391940.1\|318812_319709_+	succinyl-CoA synthetase subunit alpha	NA	NA	NA	NA
WP_011391941.1\|319721_320618_+	CoA ester lyase	NA	NA	NA	NA
WP_011391942.1\|320712_321936_+	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_011391943.1\|322107_322512_-	hydroxyphenylacetyl-CoA thioesterase PaaI	NA	NA	NA	NA
WP_011391944.1\|322550_322793_-	hypothetical protein	NA	NA	NA	NA
WP_011391945.1\|322857_324003_-	glycerate kinase	W6LM47	Streptococcus_phage	4.8e-41	38.4
WP_011391946.1\|324366_326088_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_011391947.1\|326104_326854_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.4e-28	34.9
326426:326440	attL	NA	NA	NA	NA
WP_011391948.1\|326856_327225_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_011391949.1\|327245_327803_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	9.9e-48	55.4
WP_011391950.1\|328068_329079_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_162490114.1\|329340_329874_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.1e-16	32.1
WP_053094592.1\|330016_330226_+	2-oxoisovalerate dehydrogenase	NA	NA	NA	NA
WP_025773821.1\|330222_330471_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_080996800.1\|330533_330767_+\|integrase	tyrosine-type recombinase/integrase	A0A1B0T6A8	Bacillus_phage	2.5e-05	39.7
333434:333448	attR	NA	NA	NA	NA

DBSCAN-SWA_2

2032153 : 2041036

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011393541.1\|2032153_2032771_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-21	38.0
WP_011393542.1\|2032787_2033840_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.3e-66	44.4
WP_162490084.1\|2034011_2035448_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.8e-62	37.4
WP_162490165.1\|2035411_2037589_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.6e-176	44.5
WP_011393545.1\|2037602_2038313_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_011393546.1\|2038396_2038702_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_011393547.1\|2038761_2039496_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HI61	Synechococcus_phage	2.1e-45	39.9
WP_011393548.1\|2039740_2041036_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	6.7e-23	33.2

DBSCAN-SWA_3

2050797 : 2081163

Enterobacteria_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011391836.1\|2050797_2051682_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_011391837.1\|2051726_2052068_-\|transposase	transposase	NA	NA	NA	NA
WP_080996786.1\|2052139_2053255_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_053095070.1\|2053614_2054841_-	cation:proton antiporter	NA	NA	NA	NA
WP_011393559.1\|2054843_2055335_-	cation:proton antiporter regulatory subunit	NA	NA	NA	NA
WP_053095269.1\|2055425_2056316_-	DNA polymerase domain-containing protein	NA	NA	NA	NA
WP_011393561.1\|2056550_2056814_-	hypothetical protein	NA	NA	NA	NA
WP_011393562.1\|2056829_2057261_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_025773298.1\|2057241_2057499_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_011393564.1\|2057903_2058392_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	6.9e-29	43.2
WP_162490005.1\|2058339_2058492_+	hypothetical protein	NA	NA	NA	NA
WP_011393565.1\|2058609_2059530_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_053095071.1\|2059627_2061586_-	hypothetical protein	NA	NA	NA	NA
WP_053095073.1\|2061748_2062681_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_011393568.1\|2062831_2063746_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_053095074.1\|2063985_2064669_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_053095075.1\|2064716_2065079_+	hypothetical protein	NA	NA	NA	NA
WP_011393569.1\|2065097_2065604_+	hypothetical protein	NA	NA	NA	NA
WP_071556373.1\|2066401_2066893_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_162490168.1\|2066991_2068272_+	MATE family efflux transporter	NA	NA	NA	NA
WP_011393573.1\|2069064_2069985_-	DNA polymerase domain-containing protein	NA	NA	NA	NA
WP_053095076.1\|2070288_2072580_+	PD40 domain-containing protein	NA	NA	NA	NA
WP_053095079.1\|2072815_2073070_+	hypothetical protein	NA	NA	NA	NA
WP_011393575.1\|2073218_2073530_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011393576.1\|2073519_2074191_+	SdpI family protein	NA	NA	NA	NA
WP_011393577.1\|2074247_2074985_-	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_011393578.1\|2075435_2076017_+	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_011393579.1\|2076482_2077889_-	S-layer homology domain-containing protein	NA	NA	NA	NA
WP_162490169.1\|2078005_2078506_-	ABC-2 transporter permease	NA	NA	NA	NA
WP_080996789.1\|2078476_2079025_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_011393581.1\|2079182_2079443_+	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_011392192.1\|2079675_2081163_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	5.2e-27	29.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012369

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection