CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012648	Streptococcus gordonii strain KCOM 1506 (= ChDC B679) chromosome, complete genome	4 crisprs	cas3,DEDDh,csa3,DinG,csm6,WYL	13	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012648_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012648_1

879083-879170

Orphan

Consensus_repeat	Method
CACAACTGACAAAATGTCAGTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012648_1

>merge|NZ_CP012648|1|879083-879170|CRISPRCasFinder
CACAACTGACAAAATGTCAGTTTGAGCCTTCAATCTCTTAATCTAAATTATAAAAAATTTTACGCCAAAACTGACAAAATGTCAGTTT

>NZ_CP012648|1|1|879083-879170|CRISPRCasFinder
CACAACTGACAAAATGTCAGTTT	GAGCCTTCAATCTCTTAATCTAAATTATAAAAAATTTTACGC
CAAAACTGACAAAATGTCAGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012648.1\|WP_012130907.1\|872715_872997_+\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_CP012648.1\|WP_000068664.1\|878098_878338_+\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997
NZ_CP012648.1\|WP_046164703.1\|881438_881633_+\|DUF1648-domain-containing-protein	unknown	unknown	gnl\|CDD\|377929
NZ_CP012648.1\|WP_080998581.1\|878391_879048_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP012648.1\|WP_045634142.1\|873019_874642_+\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP012648.1\|WP_080998582.1\|884090_885803_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_053794337.1\|882227_883043_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_046164702.1\|881757_882225_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_053794338.1\|883014_884013_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_046164704.1\|879828_881439_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_008809854.1\|887020_887530_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP012648.1\|WP_046164708.1\|875617_876439_-\|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|225217
NZ_CP012648.1\|WP_020992710.1\|887567_888242_-\|DUF1129-family-protein	unknown	unknown	gnl\|CDD\|227195
NZ_CP012648.1\|WP_002896497.1\|877261_877552_+\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|179034
NZ_CP012648.1\|WP_046164705.1\|879188_879902_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP012648.1\|WP_053794339.1\|885803_886823_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_008810025.1\|876486_877050_-\|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl\|CDD\|236472
NZ_CP012648.1\|WP_046164707.1\|877568_878060_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|180915
NZ_CP012648.1\|WP_046164710.1\|871751_872555_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224026
NZ_CP012648.1\|WP_045634141.1\|874765_875524_+\|epoxyqueuosine-reductase-QueH	unknown	unknown	gnl\|CDD\|224551

Protein	Function_ID	Function_description	E-value
NZ_CP012648.1\|WP_012130907.1\|872715_872997_+\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	2.52102e-33
NZ_CP012648.1\|WP_000068664.1\|878098_878338_+\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	3.32721e-37
NZ_CP012648.1\|WP_046164703.1\|881438_881633_+\|DUF1648-domain-containing-protein	gnl\|CDD\|377929	pfam07853, DUF1648, Protein of unknown function (DUF1648). Members of this family are hypothetical proteins expressed by either bacterial or archaeal species. Some of these are annotated as being transmembrane proteins, and in fact many of these sequences contain a high proportion of hydrophobic residues.	7.92321e-05
NZ_CP012648.1\|WP_080998581.1\|878391_879048_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.09886e-18
NZ_CP012648.1\|WP_045634142.1\|873019_874642_+\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP012648.1\|WP_008809854.1\|887020_887530_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13861e-07
NZ_CP012648.1\|WP_046164708.1\|875617_876439_-\|PrsW-family-intramembrane-metalloprotease	gnl\|CDD\|225217	COG2339, prsW, Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones].	6.33864e-19
NZ_CP012648.1\|WP_020992710.1\|887567_888242_-\|DUF1129-family-protein	gnl\|CDD\|227195	COG4858, COG4858, Uncharacterized membrane-bound protein conserved in bacteria [Function unknown].	1.53901e-77
NZ_CP012648.1\|WP_002896497.1\|877261_877552_+\|30S-ribosomal-protein-S6	gnl\|CDD\|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	2.20483e-39
NZ_CP012648.1\|WP_046164705.1\|879188_879902_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.04441e-90
NZ_CP012648.1\|WP_008810025.1\|876486_877050_-\|GTP-cyclohydrolase-I-FolE	gnl\|CDD\|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	8.13206e-112
NZ_CP012648.1\|WP_046164707.1\|877568_878060_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|180915	PRK07275, PRK07275, single-stranded DNA-binding protein; Provisional.	3.24446e-103
NZ_CP012648.1\|WP_046164710.1\|871751_872555_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224026	COG1101, PhnK, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	1.13379e-117
NZ_CP012648.1\|WP_045634141.1\|874765_875524_+\|epoxyqueuosine-reductase-QueH	gnl\|CDD\|224551	COG1636, COG1636, Uncharacterized protein conserved in bacteria [Function unknown].	6.90729e-95

>NZ_CP012648.1|WP_080998581.1|878391_879048_+|TetR/AcrR-family-transcriptional-regulator
MSVRCYTDHKETEIMRDVKEVEVRRAEIMSAALQLFAQKGYLKTRTQDIIDKLGISRGLLYYHFKDKEDILYCLIEKNSEPLLRKLEKISYQPNVGAKEKIRAFIEATLIPEESRTQENQVLQETVNLETNRYVLDRFYHRLCERMIVFFTHILEEGQKSGDFHLKYPHETASFLMTAYVFVSNDIKMSNEKPETLQDYLTSFQAILEKTLGLEESIF
>NZ_CP012648.1|WP_000068664.1|878098_878338_+|30S-ribosomal-protein-S18
MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
>NZ_CP012648.1|WP_046164707.1|877568_878060_+|single-stranded-DNA-binding-protein
MINNVVLVGRMTRDAELRYTPQNQAVATFTLAVNRNFKNHNGEREADFINVVIWRQQAENLANWAKKGALVGITGRIQTRNYENQQGQRVYVTEVVADNFQLLESRTSREGQSGGYTPNNFGGNAAQSFGGADSSHQVPNFSRDENPFGNSNPMDISDDDLPF
>NZ_CP012648.1|WP_002896497.1|877261_877552_+|30S-ribosomal-protein-S6
MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWEKRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKLDA
>NZ_CP012648.1|WP_008810025.1|876486_877050_-|GTP-cyclohydrolase-I-FolE
MSDFEKLQETVYQLLKLVGENPDREGLLDTPKRVAKMYQEVFSGLGRDPKDEFTAVFSEGHEEVVLVKDIPFHSMCEHHLLPFYGVAHVAYLPSNGKVTGLSKLARAVEVASKRPQLQERLTAQIATALDEALSPEGVFVMVEAEHMCMTMRGIKKPGSKTVTTVAKGIYKENVHQRQEILSMIHHD
>NZ_CP012648.1|WP_046164708.1|875617_876439_-|PrsW-family-intramembrane-metalloprotease
MKKKLVFLLFLTLICIGIEYETKTYTLGELSGKAYGIIGLAALLALLYIVPASLIILHVQKKWKTPLASLIIAFLGGLFIAGWTSGLANTYIHDGVSTLSISFINDLESAIVAPLVEEPLKLIGVAFALYLVPVKNLKSILLLGIVAGFGFQISEDFSYILSDMSEGFSFAISGILGRVVGSIASHWLYTGLTAFGLTLMIRYRKKIASNFKTGLIYFLAAFILHFIWNSPLSAIETEIPLVRPILSALAIFTFFLAYQTAARLDNDQPSLHF
>NZ_CP012648.1|WP_045634141.1|874765_875524_+|epoxyqueuosine-reductase-QueH
MIDVEEILSKMNPNQKINYDRVMQKMVQDWEKDQKRPTILMHTCCAPCSTYTLEYLSQYADVTIYFANSNIHPKAEYQRRAYVTQKFVSDFNEKTGYTVQYLEAPYAPQEFFRKVHGLEDEPEGGDRCKVCYDYRLDKTAEVAVELGFDYFGSALTISPHKNSQTINSVGIEVQKVYATHYLPSDFKKNQGYKRSVEMCEEYDIYRQCYCGCVFGAQDQGIDLVKVKKEAAAFMTGKDLEKDYSHIKFTVID
>NZ_CP012648.1|WP_045634142.1|873019_874642_+|chaperonin-GroEL
MAKDIKFSADARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGIKNVTAGANPIGIRRGIEAAVATAVEALKETAIPVSNKEAIAQVAAVSSRSEKVGEYISEAMEKVGNDGVITIEESKGMETELDVVEGMQFDRGYLSQYMVTDSEKMVADLDNPYILITDKKISNIQEILPLLESILKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQASKVTVDKDSTVIVEGSGNPEAIANRVAVIKSQIESATSEFDKEKLQERLAKLSGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVSGGGTAFVSVLDAVAGLELTGDEATGRNIVLRALEEPVRQIAFNAGFEGSIVIDRLKNSEAGTGFNAATGEWVNMIEAGIIDPVKVTRSALQNAASVASLILTTEAVVANQPEPASPAPAMDPSMMGGMM
>NZ_CP012648.1|WP_012130907.1|872715_872997_+|co-chaperone-GroES
MLKPLGDRVVLKIEEKEEKVGGFVIAGNSHAATKTATVVAVGQGVRTLTGELVAPSVKAGDKVLVESHAGVEVKDGEETYLLVSEANILAIVE
>NZ_CP012648.1|WP_046164710.1|871751_872555_+|ATP-binding-cassette-domain-containing-protein
MPLLTLTNIHKTFEKGTINENPVLRGLDLEIEQGDFISVIGGNGAGKSTLMNSIAGVVEIDEGDILLDGQSIRKSSVADRSKSISRVFQDPRMGTATNLTIEENMAIAYRRGKKRSFFKRSITEEERQIFKGALEHLGLGLENRMKTDANFLSGGQRQALTLSMATLVRPKVLLLDEHTAALDPKTSDMVMNLTKKVVEEQKLTTLMVTHNMEHAIEYGNRLIMLFHGKIVVDVKGKEKENLTVAQLMDLFHKNSGQVLNDDALVLG
>NZ_CP012648.1|WP_046164705.1|879188_879902_+|ABC-transporter-ATP-binding-protein
MLKIEHLTKVYSNGKKAVNDLSLMVEPGDIYGFIGANGAGKTSTIKAIVGIHDFDKGEIYICGHSIRKEPLLCKKKMAFLPDNPDLYKNLTARQFLDFVADVYRVSLEKRQAAIEKYSKMFELDTSLDQLISAYSHGMKQRLALIAALLHEPELLILDEPFVGLDPKGAYYFKQIMRELASQGHAIFFSTHVLEVAEELCNKVAILQKGRLVANGTTSEVKGTSSLEQVFMELQEDD
>NZ_CP012648.1|WP_046164704.1|879828_881439_+|hypothetical-protein
MERPLKLRGHLVWNKYLWSYRKMTNILLLLKVQLYNTFSLNDLRKGRGLGRYFKLGLLFLLVLLFSGYNLLTALSLVKLGQANLIPAYMIALVSFIIFFFSLMQSNGILFDQEELDRLIVLPLSIREIVYEKYAFLYLLNSVFAILLMLPAGLVWFGYGASLLELLLYLLLMGFIPLLPLCLASLLGLCVAYIASKTPHKNLVAFLFSLLLLFGLATGSMWAMRAGLSAENVGLLLTKQLTSLYPPASLFFNPQHFWWSSLLLMFVSFALTGLFLRYLSRNYLKINQMITGMSSERKAYRSCQKSPFMALYRREFANFVSSYLYMLNSGLGTILIIVLAISLCFMGPDVLFSSIGLRDSREFLPLLLASCLSISNPAAVSISLEGEEIWLLQTLPVSMRQIMMAKLALTVSLHFVALLLGLPVLTWRFSLGGLQVVDLVLISLAYSLFTALQGLVVNFHYPKFIWDNEMIVIKQSFSAILSGGIGILVLVFPLCLSLLFGMDLEISLRISALGLLLLAVVLYRHLIKQGYFKEVHG
>NZ_CP012648.1|WP_046164703.1|881438_881633_+|DUF1648-domain-containing-protein
MKKKDLFVLFLLAVILFLIICLLPEQVPIHFNRVGKADIVVNRFWLILSLPIPYSLYWKYFRSK
>NZ_CP012648.1|WP_046164702.1|881757_882225_-|hypothetical-protein
MSENKERVKVSFPWQIGLLVALYLVIASMPFLHDKTSQFYLFQNNNPIFGGKEFADLNNSYFKNSFIFLSVLPALAVLLKFILKNKGYPFLASLQSFLLFIASFVLMVYTMFSITIQRDIYKLDWGYYFCQIIFLIFIFNDLSFLRAWVKKIPSS
>NZ_CP012648.1|WP_053794337.1|882227_883043_-|hypothetical-protein
MLLKKILKINSDKWKSMLVLVCSLALLFLFFYKNLEANLKGFYANRNFPGQIKITGFSWAKERTGIDVNFTYTEKINGKKISLPLKKSVRFKQLVMPYYDKIDLSDRYNPISELGTAYDESIRVYLPMIEKMLEINPERTKLEESLTRKLNQAPNLSGASAKLRSTLSDQANFVRGETWYSDRIEDATKNKHSILEELYDFSLNHALSQGAIYVQIILPKGVDREDIHLRDQIQQLLEQLSLPDGAYVLGTIDEARGDFVVVEQGKIREGR
>NZ_CP012648.1|WP_053794338.1|883014_884013_-|hypothetical-protein
MKKLENFSWQMWQIYALAALVVFIVGGACSFFFVKEATYVVKERNYVYKGKNLRLTNYVTIGENEPEFPMIALSFKEDDNERGSSIFAVGRKYLAVQDSKQYDGTLKKKDKEEYFRIRYYQLGQEKGEGQTIDALKLVQDMGYVTINGELDNQMYSDGKNDYVKIQIDYDNEIYINLTNKKATKKRPKETIQFGYGGIYRALSDPSFITEAYSDDESNIHSYGPWFKYEKDDKESSSTGNSSDKNHSSSNVKTEDNVTLATLKKYGYLLVLKENMTLDDSETLTKILYPDASYFHWTIDSGYTKTGRKEYVETDQEFKQVIKEDAIEKDTEN
>NZ_CP012648.1|WP_080998582.1|884090_885803_+|hypothetical-protein
MIEWYYYIFIREANMDQTPFKKIIKISSFFFLALVTYLIYYPTISPEPAKREGISKNHSRTESEERYRIGVSQVNDFQKIGNIALAIDKFGEVQEKDGYLVAQNYKLPEDPYPDEGKAFYDKKNTDYFYQIDIYKEDEGIQSLKKVDVRAILLKEKKKYNIKSTAKLDVLDSSPDAPYIEIALEEIDGGPQKASLIIDLKTAKSRIAHYIGAAQEEVLTASDNSEFKIAQSNPIFADRLKSLSFIVDAKKDTNSYDNQEKQNQDKVIMMRPYQGGDLINLYQEYPHALEMAKKGSFAIYPLFKYTKDSTQQAYDFASLFNYPGEAPFWSAQKKQEYEAEQIVKQKKSPETPLPYDLFIKKVQEEGKINWAEGIVPIGLDIDSEEVVTVDFKKGPVYTQHFDLYDHISALGSLTDLSSTNTMLNQVSFDKTRRYGLKTVKDVSTLIDESKRSNPVGPQYINWLQYNPGSPLSETYMNTVKEIVEQGPLYRIFSIFSLEVGQMTVSQAETNDNLVAGSISVMVQNGNQALVPLQFKINNLHDLTPDKMIKSGRIIYVLIDGQLRRVKVPEER
>NZ_CP012648.1|WP_053794339.1|885803_886823_+|hypothetical-protein
MSQIIIKIKKLFQNKIFLNIGGYTLAFTIGLFLASYVAEKQKTTTHSQQSQTEQQEVGKNRPDKDATFKIEKLGDNLYMVENPNLAILSDKYILQQEMNYPNKTFYYDSYQQFSKDKNKNNHLKISLLNQAEGTYKDYDLLQLAQKLHPQAIPGKVSHQLYQDPQDSQLYFAFEVYLPGGSNASYYSSSSSGSFTQTLYTNIENGQTFSLDRYFEPLTAHFKQPIYSATDLDDKLNRYGLVLANKTQNITLIEGGEDLNIKSLKLSKELPGIEKKFSAGWSLMITGDDSYEKSLKLLAAEGEIDLYTNIKLDGWYSSDKKDHLLKSYQDFLNLYQKDKN
>NZ_CP012648.1|WP_008809854.1|887020_887530_+|GNAT-family-N-acetyltransferase
MGEERIVRKMLFEDIEGLSNAFVEQGWPERKDILHKYFLEQEEGERQVLVALVGRFLAGYITVIPSANHGPFAGLYPELTDFNVFESFQRQGIGTALIEKAEQEALKYSDVVTLGVGLHKGYGPAQRLYIKRGYIPDGSGLWFNNEALAPYAPCENSDDLVLYFSKKRK
>NZ_CP012648.1|WP_020992710.1|887567_888242_-|DUF1129-family-protein
MSQVSIDKLSKKNQEFIRIATHQLIEAGKTDEEIKVLLEEIIPTILENQSKGITARGLYGSPTAWVQQLTAAEKKAAENPAQNDDPRLMILDSALLIFGLLSIFQGAVNYFAKTPNPYGFTTLVLGSLTGGLVFYSLYHFIYRYYEPDQEYGTKPPFWKSAIVMSGAVLLWLVAFTLSAFLPSFLNPQLPNLLVIMIGGLALVGRWYLKKKFNIKSATANPRRY

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Crispr_ID: NZ_CP012648_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012648_2

1030217-1030289

Orphan

Consensus_repeat	Method
ATAGTTCTCACGGAAACTTTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012648_2

>merge|NZ_CP012648|2|1030217-1030289|CRISPRCasFinder
ATAGTTCTCACGGAAACTTTTTTCTTGACTTTCGCTTTTGAAGTGGTAGAATAGTTCTCACGGAAACTTATTT

>NZ_CP012648|2|2|1030217-1030289|CRISPRCasFinder
ATAGTTCTCACGGAAACTTTTTT	CTTGACTTTCGCTTTTGAAGTGGTAGA
ATAGTTCTCACGGAAACTTATTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012648.1\|WP_046164614.1\|1025424_1027236_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP012648.1\|WP_046164750.1\|1030774_1032541_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP012648.1\|WP_053794400.1\|1035834_1037448_+\|CTP-synthase	unknown	unknown	gnl\|CDD\|235437
NZ_CP012648.1\|WP_053794398.1\|1019013_1019628_+\|DUF624-domain-containing-protein	unknown	unknown	gnl\|CDD\|227865
NZ_CP012648.1\|WP_012130786.1\|1034448_1035393_+\|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl\|CDD\|224399
NZ_CP012648.1\|WP_053794399.1\|1019624_1021259_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_CP012648.1\|WP_046164611.1\|1029064_1029475_+\|peptide-deformylase	unknown	unknown	gnl\|CDD\|181704
NZ_CP012648.1\|WP_008809687.1\|1041317_1042103_+\|ABC-2-family-transporter-protein	unknown	unknown	gnl\|CDD\|226218
NZ_CP012648.1\|WP_046164605.1\|1039509_1040496_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226952
NZ_CP012648.1\|WP_046164610.1\|1029483_1030053_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_046164615.1\|1024174_1025098_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|376134
NZ_CP012648.1\|WP_046164613.1\|1027351_1027876_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_008809690.1\|1038335_1039217_+\|fructose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|180926
NZ_CP012648.1\|WP_046164616.1\|1022685_1024071_+\|glycoside-hydrolase-family-1-protein	unknown	unknown	gnl\|CDD\|225343
NZ_CP012648.1\|WP_046164617.1\|1021268_1022552_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_CP012648.1\|WP_012130789.1\|1030323_1030782_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP012648.1\|WP_008809688.1\|1040497_1041316_+\|ABC-2-family-transporter-protein	unknown	unknown	gnl\|CDD\|226953
NZ_CP012648.1\|WP_008809691.1\|1037517_1037928_+\|effector-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379638
NZ_CP012648.1\|WP_046164612.1\|1028116_1029016_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|366120
NZ_CP012648.1\|WP_046164609.1\|1032530_1034288_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055

Protein	Function_ID	Function_description	E-value
NZ_CP012648.1\|WP_046164614.1\|1025424_1027236_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP012648.1\|WP_046164750.1\|1030774_1032541_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.64598e-139
NZ_CP012648.1\|WP_053794398.1\|1019013_1019628_+\|DUF624-domain-containing-protein	gnl\|CDD\|227865	COG5578, COG5578, Predicted integral membrane protein [Function unknown].	8.33262e-28
NZ_CP012648.1\|WP_012130786.1\|1034448_1035393_+\|mannose-6-phosphate-isomerase,-class-I	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.76536e-146
NZ_CP012648.1\|WP_046164617.1\|1021268_1022552_+\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.43468e-110
NZ_CP012648.1\|WP_046164611.1\|1029064_1029475_+\|peptide-deformylase	gnl\|CDD\|181704	PRK09218, PRK09218, peptide deformylase; Validated.	3.68081e-93
NZ_CP012648.1\|WP_008809687.1\|1041317_1042103_+\|ABC-2-family-transporter-protein	gnl\|CDD\|226218	COG3694, COG3694, ABC-type uncharacterized transport system, permease component [General function prediction only].	1.83488e-108
NZ_CP012648.1\|WP_046164605.1\|1039509_1040496_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226952	COG4586, COG4586, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	3.58444e-180
NZ_CP012648.1\|WP_046164615.1\|1024174_1025098_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|376134	pfam18710, ComR_TPR, ComR tetratricopeptide. In Gram-positive bacteria, cell-to-cell communication mainly relies on extracellular signaling peptides. ComR is a member of the RNPP family, which positively controls competence for natural DNA transformation in streptococci. It is directly activated by the binding of its associated pheromone XIP. The crystal structure analysis of ComR shows that it contains an N-terminal helix-turn-helix (HTH), DNA binding domain (DBD) and a C-terminal tetratricopeptide repeat (TPR) domain. The TPR domain is composed of 11 alpha-helices forming 5 TPR motifs followed by an additional C-terminal alpha-helix 16 called CAP. The pheromone XIP binding site is found in the TPR region. Biochemical and mutational analysis indicate that, if the interacting XIP is accepted it can then trigger the conformational change of the TPR domain to open the DBD-TPR interface to allow dimer formation that is required to bind DNA.	1.62208e-47
NZ_CP012648.1\|WP_053794400.1\|1035834_1037448_+\|CTP-synthase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP012648.1\|WP_008809690.1\|1038335_1039217_+\|fructose-bisphosphate-aldolase	gnl\|CDD\|180926	PRK07315, PRK07315, fructose-bisphosphate aldolase; Provisional.	0
NZ_CP012648.1\|WP_046164616.1\|1022685_1024071_+\|glycoside-hydrolase-family-1-protein	gnl\|CDD\|225343	COG2723, BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism].	0
NZ_CP012648.1\|WP_053794399.1\|1019624_1021259_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.98072e-63
NZ_CP012648.1\|WP_012130789.1\|1030323_1030782_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.8344e-09
NZ_CP012648.1\|WP_008809688.1\|1040497_1041316_+\|ABC-2-family-transporter-protein	gnl\|CDD\|226953	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only].	1.465e-93
NZ_CP012648.1\|WP_008809691.1\|1037517_1037928_+\|effector-binding-domain-containing-protein	gnl\|CDD\|379638	pfam14526, Cass2, Integron-associated effector binding protein. This family contains Cass2 from Vibrio cholerae, an integron-associated protein that has been shown to bind cationic drug compounds with submicromolar affinity. Cass2 has been proposed to be representative of a larger family of independent effector-binding proteins associated with lateral gene transfer within Vibrio and other closely-related species.	1.26829e-07
NZ_CP012648.1\|WP_046164612.1\|1028116_1029016_+\|ROK-family-protein	gnl\|CDD\|366120	pfam00480, ROK, ROK family.	1.39503e-83
NZ_CP012648.1\|WP_046164609.1\|1032530_1034288_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.8457e-172

>NZ_CP012648.1|WP_046164610.1|1029483_1030053_+|hypothetical-protein
MKVYKRDGSTFYFIGFLLLLGIFFTMAFASLDKQTTALESQNNANQIIYRNPISKEDERSGQTSEESDVMLNMVYWGVGIIAILMFVLGYISNHRPPILEMDQSGMRLRGLSDKSEKFFLWQEIEMIEYDLYRSHRTSADPDIRILYFYPKDQDASAISLNLDHVKDVSFNELHQQISELAPHIKWLFP
>NZ_CP012648.1|WP_046164611.1|1029064_1029475_+|peptide-deformylase
MQQAIVKDILFLQQKSEVAVKSDLYLAQDLQDTLLANQENCVGLAANMIGVKKRVIIFMYGMVPIIMFNPVLRAKSGPYQTEEACLSLVGSRSTTRYQEITVDYLDRNWQPQTITLKDFPAQICQHELDHLEGILI
>NZ_CP012648.1|WP_046164612.1|1028116_1029016_+|ROK-family-protein
MTKLYGSLEAGGTKFVCAVGDEKFEIVEKTQFPTTTPIETLDKTIEFFSRFENLAGLAVGSFGPIDIDQNSKTYGFITTTPKPHWANVDIVGVLRRALNVPIYFTTDVNSSAFGEVVARNNAGGRIENLVYYTIGTGIGAGAIQRGEFIGGAGHPEMGHYYVAKHPMDVEKEFNGVCPFHNGCLEGLAAGPSLEARTGIRGENIELNSSVWDIQAYYIAQAAIQATVTFRPDVIVFGGGVMAQQHMLDRVREKFAVLLNGYLPVPDVRDYIVTPAVAGNGSATLGNFVLAKEISERHAK
>NZ_CP012648.1|WP_046164613.1|1027351_1027876_+|hypothetical-protein
MKKKGNVISLIVGLVFGSSFLVRTFLIYQAREAKRQEVAKVKDVQKTIQSLDEKRSEEVKKQLSKTLSSALASRSAYEKYTQIDNQYALGVRAGAYYLVTLSTKEERLLEGVDQAFSTTYKDEDNGETGVALLGHKDGVWHVLDEKGETIITLEQTDISPESKMIIKNNTVSFQ
>NZ_CP012648.1|WP_046164614.1|1025424_1027236_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVTTGKNSSLVKSVGRIADLRSKIGIDVAGSTGIGHTRWATHGKPSESNAHPHRSETGRFVLVHNGVIENYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFVEEDGLLVLEAFKKALHIIRGSYAFALVDSEDSEVIYVAKNKSPLLVGLGEGYNMVCSDAMAMIRETNQFMEIHDQELVIVRKDSVEVQDYDGNLQERESYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDENGQVVVDPAIVKAVQEADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPLLSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANHTMLLHAGPEIAVASTKAYTAQIAALAFLAKAVGDANASEKAAAFDLVHELSLVAQSIESTLSEKELIENKVDNLLGTTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALIEEGTPVLALLSDPVLANHTRGNIQEVAARGANVLTIAEENVAKDNDDIVLSQVHPYLSPISMVVPTQLVAYYATLHRGLDVDKPRNLAKSVTVE
>NZ_CP012648.1|WP_046164615.1|1024174_1025098_+|helix-turn-helix-domain-containing-protein
MDFKTELGQRIQNLRESKGLSRQAICDLEDVLTTRQLQRIEKGQSLPTIATAKYIADKLDVSLDVLANNNSLALPLEYIDLKYQLRTLYHYGDPERLRLLEKIIDEIYENHFENLPEEEQLSIQVVQATVDMIGAKDPSFDQGLLDEYLEQAMKKKELSFNDVEIIQLRLLSLALGDFNQEEFVDLLSKVILAADYFPLSELEKVQNTIVSAAGVLAHYGIYEILPDIVNVLNDIMTKRRDFQDNIFVHALNWKVALFIEDNLEKAKNDYQKVCMMADLLSEDLVKRNMQEEWIEDLEKKGLKYTKI
>NZ_CP012648.1|WP_046164616.1|1022685_1024071_+|glycoside-hydrolase-family-1-protein
MLTFPKDFVWGSSTSGPQTEGRVPGDGKGDNLWDYWYQVEPNRYYNEIGPEQTSTFYQHWEQDIDLLVETGHTAFRTSIQWSRIFPQGRGEVNHQGVAFYRQVFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATIKAYVDYARFCFETYGDLVDQWITFNEPIVPVEFGYFYDAHYPHKVDAKAAVQVAYHTQLASTLAVKVCHEILPDSKIGIVLNLTPAYPRSQHPADVKAARIADLFQAQSFLDPSVLGTYPEELVEILSEHDLLPDYTAEELELIREHTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYDMPGRKINPHRGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEERFREDGFIQDDYRIDFVKGHLRQLHRAIQDGANCTGYLMWTFIDCWSWLNSYKNRYGLIELNLETQERIIKKSGYWFRKLSQQNGFEE
>NZ_CP012648.1|WP_046164617.1|1021268_1022552_+|response-regulator-transcription-factor
MHKVLLVDDEYMITEGLKVLIPFEKWNMEVVATANDAEEALDYVKNHPVDLVITDVNMPGMNGLEMIAQMKESLPKLAFIILSGYQEFEYVKKALNLQVADYLVKPVNKVELAAILEKLSQQFDQSSHYQMEAIFQDGLSEEDLTRLLEKEETIWLGASRVPQGIASTSYSVSGQNLYLFLSRTKEESLYQIELVSPYKENLQQFKSNLEKVVFYGTVGLQQADPLFQYYEPMYRVIIQGNINQILDELDLLKGVVLSHTPRISITKQLFIQFMMDVYHLFEHLKPDDMTSIIKEIEGMMSFEDLLDYIKQKLTHLFAQYRMNENVASVLEVIGRDYQKDLSLKDISKDLFINPVYLGQLIKRETNSTFAELLNKQRIKAAQQLLLSTNDSIEDVCYAVGYSNVGYFYKVFRKLCGKSPKAYRQQVD
>NZ_CP012648.1|WP_053794399.1|1019624_1021259_+|sensor-histidine-kinase
MKKFWLNSLLRVYAMTMFVIVGFVALLISYASWQSKVQEVTETSQRISTRLVDEVESYYQRGVQITKSLVGNQAKLEGVYNYFTMSPSEYIYWRLNNGLLGIVEVSLHENIADIYLQNDFVAGFDVALQDYKTVFVSTRQKQGGMQVEASKYKPAKNAFPIPIYDSVTSNHIGVAYLTIDSQVFEQTIDNIRNTTPVLVKITSPFQKNMLTFGEGKSKNWLVKETPHGYGVQVAVPEHYVLERSLVNALAIVAISAILTGSLYLILQRVFRNYQSQVIDLVDTIQAIGQGDSHLRIETATKEQELLLIADNTNTMLDNLDRNIHDIYQLQLSQKDANMRALQAQINPHFMYNTLEFIRMYAVMKSQEELADIIYEFSSLLRNNISDETQVTLESELEFCRKYSYLCMVRHPNSVAYGFTIAEELKGMIIPKFTIQPLVENYFVHGVDYRRKDNVISVKVLKKSDAVQIIVQDNGRGIKADKLAEIQQILANRQLENSENKEKRTSIGIINIHERFLLFFGDRYSIAVESGENRGVRYIIEIKDE
>NZ_CP012648.1|WP_053794398.1|1019013_1019628_+|DUF624-domain-containing-protein
MGKFIELIFQKIYMAMLASGIFLVLTLCGGVLFGLAPASTVLMTLFAQYRYDYKAYKWQEAWSLFKENFLRSNQVFYTLLSIEAVFLYGLYLLVQLPQSILTVIISILNLLLALLLPLAYAVYLKLQVYFELSYINSIKLSFIGMFLNVGAMFKIAFGTAMIMAIFYYMPALVFFVFLGAWHFFISDLLEPVYQLIASRLVDQP
>NZ_CP012648.1|WP_012130789.1|1030323_1030782_+|MarR-family-transcriptional-regulator
MEKPLLEFKRFGRKTQRIIEKRAKVCGMEFMGGPQGQVLHIVSHRAKRGLSTFIRDIEHELDISKSVASNLIKRMEKNGSIFLEVSETDKRAKMIHLTAQSKQQLKELHDFFNEIDRCLLQGVSEEELATFTLVMAKFHQNIEKLESEDANV
>NZ_CP012648.1|WP_046164750.1|1030774_1032541_+|ABC-transporter-ATP-binding-protein
MFKLFKRLTSKEIGLILMTVVFICLTVYLELEVPTYMSEITTLLQTPGTTTGDLWVPGLKMLGLSFASLFSLVIAGFVSSRMASSYTTRLREDIFNRVLDYSNSEIKKFSIPSLLTRTTNDITQIQVFIAMGLQVVIRGSIMAIWAMTKVVGKSDAWLIAVLVAVAAIILMTIVLVTLAFPKQSIVQTLTDKLNSVTRESLTGIRVVRAYNAEDYQDAKFGAANDEVTSLNIFINRFMSLFNPIMSGISSGLTLAIYWIGAYLIHSAASADKLGLFSDMVVFMSYGMQVVIGFLLMGALFIVLPRTLVSAGRINKVLAVDSSIKEKDQAQTEGQSKGQVAFEDVSFRYAKNSEAVIEHVSFTAKAGETVAFIGSTGSGKSTLVNLITRFYDVTEGRILVDGIDVRDYELKALRNKVGYIPQKAVLFSGTIASNLDFGESMETPLDEEKMWEALELAQAKSFVEEKEAGLESKVAQGGTNYSGGQRQRLAIARALARKPEILIFDDSFSALDYKTDRILRKELAEQTQHMTKLIVAQRISTIMDADQILVLDNGKVVGQGTHKELLATNEVYQEIAYSQLSKEELENGK
>NZ_CP012648.1|WP_046164609.1|1032530_1034288_+|ABC-transporter-ATP-binding-protein
MENKKTSLFTQMKPYIKGFQLPFVIAVAGAIISSIITVFGPYKLREITNLITEGLVGEMDLGAISNIGFFLAFLYVVGSLINYAQGYAISDMIQHFSKRLRTAIAEKINRLPLSYFDSHSQGDTLSRVTNDVDTVGQSLTQSLGTLISSVLLLIAVLFMMFYTNVVLSFVTIGSVLLGFVFSAVLMAKSQRYFQEQQSNLAAINGYVEEMYSGHNVITSYNGAEKTRLAFNALNQNLYTSMWKSQFISGIMFPLMNFVGNFGYVMVVIVGATMAINGSISMGTIVAFMVYVRIFSQPLSQIAQGITTLQSASAAMGRVFEFLAEEDMEDDSHKLQQLTSVKGRVQFKDVFFGYNPDKTIIHDFSAEAKAGQKIAIVGPTGAGKTTIVNLLMKFYDIDRGRITIDGVDTKEMKRSEVHDAFSMVLQDTWLFEGTIKENLIYNQKDITDQAVVEAAKAVGVHHFIMTLPDGYDTVLDDTVSLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQKAMDKLMEGRTSFVIAHRLSTIRNADLILVMRDGNIIEQGNHDQLMEQGGFYADLYNSQFVEEDQE
>NZ_CP012648.1|WP_012130786.1|1034448_1035393_+|mannose-6-phosphate-isomerase,-class-I
MSEPLFLQSVMHEKIWGGTKLRDEFGYEIPSDKVGEYWAISAHPNGVSTVKNGRFAGQKLDTLYAEHRELFGDRSEPVFPLLTKILDANDWLSVQVHPDDAYGLKHEGELGKTECWYIIAADEGAEIIYGHNAKSKEELREQIESKNWDQLLTKVKVKAGDFFYVPSGTMHAIGSGILILETQQSSDTTYRVYDFDRKDDAGNLRELHLEKSIDVLNIGEPANSRPVNLQVDNLSSTLLVANDFFAVYKWELTGQADFTKTADYTLNSVLNGQGQLTVDGQVYPIHKGDHFILPSDVASWKLEGHDLEMIVSHP
>NZ_CP012648.1|WP_053794400.1|1035834_1037448_+|CTP-synthase
MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKERKGEYLGATVQVIPHITDALKDKIKRAARTTDSDVIITEVGGTVGDIESLPFLEALRQMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEQPVGQNIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQKMDQIVCDHLKMDVPVADMTEWSAMVEKVMNLKKQVRIALVGKYVELPDAYISVVEALKHAGYANDAEVKIDWIDANQVTAENVAELLGNADGIIVPGGFGQRGTEGKIQAIRYAREQDVPMLGICLGMQLTCVEFARHVLELADANSAELNPDTPYPIIDLMRDQIDVEDLGGTLRLGLYPSKLKHGSKAAAAYDHQEVVQRRHRHRYEFNNDFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQYHPELSSRPNRPEGLYTAFVTAAVEKSSER
>NZ_CP012648.1|WP_008809691.1|1037517_1037928_+|effector-binding-domain-containing-protein
MFLNILASIRTNNFQDEHCIEKIQTLWQEQEGTVKEAFAQGEPVYAVYHDYASDYKGDYNLSICRLTDGDVYDFDTSEQTYQVFEADKEDPQAILHAWQRIWQAEETGELHRGYTFDFEKYDPDQTVAVFVATQQP
>NZ_CP012648.1|WP_008809690.1|1038335_1039217_+|fructose-bisphosphate-aldolase
MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVCKALIENLVESMGITVPVAIHLDHGHYEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAKAMVATGIDFLAAGIGNIHGPYPANWEGLDLDHLKKLTEALPGFPIVLHGGSGIPDDQIQAAIKLGVAKVNVNTECQIAFANATRQFVREYDANEAEYDKKKLFDPRKFLKPGFEAITAAVEERIDVFGSEGKA
>NZ_CP012648.1|WP_046164605.1|1039509_1040496_+|ATP-binding-cassette-domain-containing-protein
MIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLTFEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVVFGQRTQLWWDLALQETYTVLKEIYDVPDTLFHKRMDFLNEVLDLKDFIKDPVRTLSLGQRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLSDIEQLCDRIFMIDKGQEIFDGTVSQLKESFGKMKTLSFELLPGQSHLVSHYEGLPDMTIEKQGNSLNIEFDSSHYQSADIIKQTLSDFEVRDLKMVDTDIEDIIRRFYRKEL
>NZ_CP012648.1|WP_008809688.1|1040497_1041316_+|ABC-2-family-transporter-protein
MVKLWRRYKPFINAGIQELITYRVNFLLYRIGDVMGAFVAFYLWKAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTKSDSSFMIGEEVKDGSIIIRLLRPVHFAASYLFTELGSKWLIFISVGVPFLCVIVLVKILSGQGIVEVLGLTVLYLFSLTLAYLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPFSSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG
>NZ_CP012648.1|WP_008809687.1|1041317_1042103_+|ABC-2-family-transporter-protein
MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFLNVIFQHIPSLEGWTFQEIAFIYGFSLIPKGLDHLFFDNLWALGQRLVRKGEFDKYLTRPINPLFHILVETFQIDALGELLVGGILLATTVSSIAWTLPKFLIFLVCIPFATLIYTSLKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPASYFLQNKNGLFNIGGLILISLVFFFISLKLWDRGLDAYESAGS

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Crispr_ID: NZ_CP012648_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012648_3

1202494-1202638

Orphan

Consensus_repeat	Method
GTCTGGGAGACATTTTTAGGTTG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP012648_3

>merge|NZ_CP012648|3|1202494-1202638|CRISPRCasFinder
GTCTGGGAGACATTTTTAGGTTGCAGATGGGAACTCGCAACAGCGAGTTTTCTTCAAACAGTCTGGGAGACATTTTTAGGTTGTGGATAGAAAGTTACGAAAATAACTTAACATTTAAAAAGGTCCAGTGGACCTTTTTAAGTTG

>NZ_CP012648|3|3|1202494-1202638|CRISPRCasFinder
GTCTGGGAGACATTTTTAGGTTG	CAGATGGGAACTCGCAACAGCGAGTTTTCTTCAAACA
GTCTGGGAGACATTTTTAGGTTG	TGGATAGAAAGTTACGAAAATAACTTAACATTTAAAAAG
GTCCAGTGGACCTTTTTAAGTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012648.1\|WP_008809542.1\|1214171_1214420_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_046165258.1\|1208461_1208848_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|378129
NZ_CP012648.1\|WP_045635067.1\|1197863_1199030_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380570
NZ_CP012648.1\|WP_008809559.1\|1196836_1197427_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
NZ_CP012648.1\|WP_046165249.1\|1191570_1192737_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|224090
NZ_CP012648.1\|WP_046165255.1\|1205030_1206245_-\|aminoacyltransferase	unknown	unknown	gnl\|CDD\|367067
NZ_CP012648.1\|WP_045635066.1\|1197504_1197774_+\|YlbG-family-protein	unknown	unknown	gnl\|CDD\|179410
NZ_CP012648.1\|WP_045635065.1\|1196005_1196635_+\|uracil-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234653
NZ_CP012648.1\|WP_046165253.1\|1203055_1203712_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341361
NZ_CP012648.1\|WP_008809541.1\|1214451_1215198_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP012648.1\|WP_046165252.1\|1200061_1201015_+\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119323
NZ_CP012648.1\|WP_046165256.1\|1206244_1207054_-\|sugar-phosphatase	unknown	unknown	gnl\|CDD\|182509
NZ_CP012648.1\|WP_053794451.1\|1209068_1211765_+\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319781
NZ_CP012648.1\|WP_046165257.1\|1207055_1208357_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP012648.1\|WP_046165254.1\|1203780_1205016_-\|aminoacyltransferase	unknown	unknown	gnl\|CDD\|367067
NZ_CP012648.1\|WP_053794452.1\|1212312_1213857_+\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
NZ_CP012648.1\|WP_012130688.1\|1201014_1201779_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223488
NZ_CP012648.1\|WP_046165250.1\|1193247_1195908_+\|magnesium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319772
NZ_CP012648.1\|WP_008809556.1\|1199188_1200058_+\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223633
NZ_CP012648.1\|WP_008809553.1\|1201778_1202489_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223487

Protein	Function_ID	Function_description	E-value
NZ_CP012648.1\|WP_046165258.1\|1208461_1208848_+\|DUF1934-domain-containing-protein	gnl\|CDD\|378129	pfam09148, DUF1934, Domain of unknown function (DUF1934). Members of this family are found in a set of hypothetical bacterial proteins. Their precise function has not, as yet, been defined.	3.65484e-22
NZ_CP012648.1\|WP_045635067.1\|1197863_1199030_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380570	cd06347, PBP1_ABC_LivK_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.	1.02655e-136
NZ_CP012648.1\|WP_008809559.1\|1196836_1197427_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	2.2753e-128
NZ_CP012648.1\|WP_046165249.1\|1191570_1192737_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	0
NZ_CP012648.1\|WP_046165255.1\|1205030_1206245_-\|aminoacyltransferase	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	6.94687e-148
NZ_CP012648.1\|WP_045635066.1\|1197504_1197774_+\|YlbG-family-protein	gnl\|CDD\|179410	PRK02302, PRK02302, hypothetical protein; Provisional.	7.47521e-43
NZ_CP012648.1\|WP_045635065.1\|1196005_1196635_+\|uracil-phosphoribosyltransferase	gnl\|CDD\|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	3.37033e-142
NZ_CP012648.1\|WP_046165253.1\|1203055_1203712_+\|CBS-domain-containing-protein	gnl\|CDD\|341361	cd04584, CBS_pair_AcuB_like, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the ACT domain. The putative Acetoin Utilization Protein (Acub) from Vibrio Cholerae contains a CBS pair domain. The acetoin utilization protein plays a role in growth and sporulation on acetoin or butanediol for use as a carbon source. Acetoin is an important physiological metabolite excreted by many microorganisms. It is used as an external energy store by a number of fermentive bacteria. Acetoin is produced by the decarboxylation of alpha-acetolactate. Once superior carbon sources are exhausted, and the culture enters stationary phase, acetoin can be utilised in order to maintain the culture density. The conversion of acetoin into acetyl-CoA or 2,3-butanediol is catalysed by the acetoin dehydrogenase complex and acetoin reductase/2,3-butanediol dehydrogenase, respectively. Acetoin utilization proteins, acetylpolyamine amidohydrolases, and histone deacetylases are members of an ancient protein superfamily.This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the acetoin utilization proteins in bacteria. Acetoin is a product of fermentative metabolism in many prokaryotic and eukaryotic microorganisms. They produce acetoin as an external carbon storage compound and then later reuse it as a carbon and energy source during their stationary phase and sporulation. In addition these CBS domains are associated with a downstream ACT (aspartate kinase/chorismate mutase/TyrA) domain, which is linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Pairs of ACT domains bind specifically to a particular amino acid leading to regulation of the linked enzyme. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	2.07307e-60
NZ_CP012648.1\|WP_008809541.1\|1214451_1215198_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.52361e-07
NZ_CP012648.1\|WP_046165252.1\|1200061_1201015_+\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	2.67329e-68
NZ_CP012648.1\|WP_046165256.1\|1206244_1207054_-\|sugar-phosphatase	gnl\|CDD\|182509	PRK10513, PRK10513, sugar phosphate phosphatase; Provisional.	7.99489e-122
NZ_CP012648.1\|WP_053794451.1\|1209068_1211765_+\|cation-translocating-P-type-ATPase	gnl\|CDD\|319781	cd02089, P-type_ATPase_Ca_prok, prokaryotic P-type Ca(2+)-ATPase similar to Synechococcus elongatus sp. strain PCC 7942 PacL and Listeria monocytogenes LMCA1. Ca(2+) transport ATPase is a plasma membrane protein which pumps Ca(2+) ion out of the cytoplasm. This prokaryotic subfamily includes the Ca(2+)-ATPase Synechococcus elongatus PacL, Listeria monocytogenes Ca(2+)-ATPase 1 (LMCA1) which has a low Ca(2+) affinity and a high pH optimum (pH about 9) and may remove Ca(2+) from the microorganism in environmental conditions when e.g. stressed by high Ca(2+) and alkaline pH, and the Bacillus subtilis putative P-type Ca(2+)-transport ATPase encoded by the yloB gene, which is expressed during sporulation. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP012648.1\|WP_046165257.1\|1207055_1208357_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.67175e-157
NZ_CP012648.1\|WP_046165254.1\|1203780_1205016_-\|aminoacyltransferase	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NZ_CP012648.1\|WP_053794452.1\|1212312_1213857_+\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NZ_CP012648.1\|WP_012130688.1\|1201014_1201779_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223488	COG0411, LivG, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	1.7088e-132
NZ_CP012648.1\|WP_046165250.1\|1193247_1195908_+\|magnesium-translocating-P-type-ATPase	gnl\|CDD\|319772	cd02077, P-type_ATPase_Mg, magnesium transporting ATPase (MgtA), similar to Escherichia coli MgtA and Salmonella typhimurium MgtA. MgtA is a membrane protein which actively transports Mg(2+) into the cytosol with its electro-chemical gradient rather than against the gradient as other cation transporters do. It may act both as a transporter and as a sensor for Mg(2+). In Salmonella typhimurium and Escherichia coli, the two-component system PhoQ/PhoP regulates the transcription of the mgtA gene by sensing Mg(2+) concentrations in the periplasm. MgtA is activated by cardiolipin and it highly sensitive to free magnesium in vitro. It consists of a transmembrane domain and three cytosolic domains: nucleotide-binding domain, phosphorylation domain and actuator domain, and belongs to the P-type ATPase type III subfamily. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP012648.1\|WP_008809556.1\|1199188_1200058_+\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|223633	COG0559, LivH, Branched-chain amino acid ABC-type transport system, permease components [Amino acid transport and metabolism].	1.89574e-80
NZ_CP012648.1\|WP_008809553.1\|1201778_1202489_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223487	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	4.88655e-132

>NZ_CP012648.1|WP_008809553.1|1201778_1202489_+|ABC-transporter-ATP-binding-protein
MTMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTTILRTISGLVRPSAGKIEFLGNEIQKVPAQKIVAAGLSQVPEGRHVFPGLTVMENLEMGAFLKTNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLLDEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALSIANRGYVLETGKIVLSGTGQELLASDEVRKAYLGG
>NZ_CP012648.1|WP_012130688.1|1201014_1201779_+|ABC-transporter-ATP-binding-protein
MALLDVKNLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTTLFNLLTGVYEPSEGTVTLDGHLLNGKAPYKIASLGLGRTFQNIRLFKDLTVLDNVLIAFGNHHKPHTFASFFRLPAFYKNEEELKNKALDLLKIFDLDKEAETLAKNLAYGQQRRLEIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKNEFNITIMLIEHDMSLVMEVTERIYVLEYGRLIAHGTPDEIKSNERVIEAYLGGEA
>NZ_CP012648.1|WP_046165252.1|1200061_1201015_+|branched-chain-amino-acid-ABC-transporter-permease
MKQNLKVNLLWLALILAGFVLITVLAGGGILNAFHLQILEEIGINIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAVAIIGTKSPTYPAFFAAMILGAFIAGLVALGVGIPTLRLKGDYLAIATLGVSEIIRILIVNGGEVTNGAAGILSIPGFTSWQMVYFFVVITTLFTLNFLRSPLGRKTLSVREDEIAAESVGVNTTKAKVVAFVFGAITASIAGALKAGFIGAVVPKDYSFTNTINVLIIVVFGGLGSMTGTVIAAIVLGILNMLLQEFSSIRMIIYSLALILVMIFRPGGLLGTWELQLSRFFKKDKEVKE
>NZ_CP012648.1|WP_008809556.1|1199188_1200058_+|branched-chain-amino-acid-ABC-transporter-permease
MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGAFMGYFLINSLKLNFFLALIVAMIGTAILGVVIEFLAYRPLRNSTRIAALITAIGVSFLLEYLMVYFVGASTLPFPQVIPTVRFNLGPITVSNIQLMILGISIFLMLALQFIVQKTKMGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGMTPGIKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILIIILLIRPAGILGKNVKEKV
>NZ_CP012648.1|WP_045635067.1|1197863_1199030_+|ABC-transporter-substrate-binding-protein
MKKKFALTLVSLASVALLAACGEVSTTGNSGSASGTEIGKTLKIGFNFEETGDVASYGTAEQKAAKLAVDEINKAGGVDGKQIEITDKDNKSELSEASTVSTNLVTQAKVNAIIGPATSGGTGAAITNAAKASVPLITPSGTQDDLTKGQDYLFRTTFIDSFQGKILSKYVTDNLKAKKVVLYYDNSSDYAKGIAKAFQEEYKGEIVATETFASKDTDFQAALTKFKGKDFDALVVPGYYTEAGKIVNQARGMGIDKPIVGGDGFNSEEFISQATPAAATNVYYVSGYSTSGDMTAKAKKFLEAYKAKYNEEPSMFSALAYDSVYMVAEASKGAKNSVDIKENLAKLKDFEGVTGSITMDKNHNPVKSALMIGLKDGKVDTVETVKPN
>NZ_CP012648.1|WP_045635066.1|1197504_1197774_+|YlbG-family-protein
MYQKEERVGVIVYLYYNRDVKKVAAYGDIVYHSKKRRYLQLYVPKMQAEDLQKKLGQEKFVKKVRACHIQELDKNFVGSLHRQEENVII
>NZ_CP012648.1|WP_008809559.1|1196836_1197427_+|ATP-dependent-Clp-protease-proteolytic-subunit
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGKTVEQIHADAERDYWMSAEETLAYGFIDEIMANNNLS
>NZ_CP012648.1|WP_045635065.1|1196005_1196635_+|uracil-phosphoribosyltransferase
MGKLEVIAHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEVLRDLPLEDVEIETPITKTVQKQIAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRDEETLKPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASHITFVCLVSAPEGVEALQEAHPDVDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK
>NZ_CP012648.1|WP_046165250.1|1193247_1195908_+|magnesium-translocating-P-type-ATPase
MKIVKERLVAALQLPMQETLAFYKTAFRGLTEEQVEENRDLYGENIITKGQEDSILKKIYESIINPFTVILLVIALVSLVTNVWLAKPGEEDPTTSIIIVVLVLISGGIRFIQELRSDRAASNLSRLIVNTATVIREGVEQELPIDEIVVGDIVKLSAGDMIPADVLLLESRDFFVQQSGLTGESDAVEKICLSKSDGQNLDSLLETESLAFMGTNVISGRATALVLVVGDDTMMGAIEQTLNTYDEPTSFERDMNSISWLLIRLMLVMVPVVFFINGLTDGDWLEAGVFALSVGVGLTPEMLPMIITASLAKGSIIMAQEKVVIKKLNAIQDLGAIDILCTDKTGTLTQDEIVLEYPLDIHGDLDLAVLRRAFLNSYYQTGLKNLMDRAIINRTEKEAEKHELVRDLDQTFKKIDELPFDFERRRMSVIVKDDEDVISMVTKGALEEMLAISSYVEYKNRITELTEEIRQEILAEVAQLNEQGLRVLGVSYKSDLEEDYDYEVKDESDMILTGYLAFLDPPKSSAAPAIETLAEYGVATKILTGDNEKVTQAVCEKVGLDVENILLGVEVDALSDEELSKAVENTTVFAKLSPDQKARIILQLKANGHKVGYMGDGINDAPSMKVADVGISVDTAVDIAKETADVILLDKDLMVLEKGLVEGRKVYANMTKYIKMTVSSNFGNIFSLLFASIFLPFLPMAPVHLIVLNLVYDLSCIALPFDNVDSEFLKKPRIWSANSITRFMAWIGPISSIFDVLTYLALYFIIVPMITGSSYQAGTEQAATFITLFQTGWFIESMWTQTMVIYMLRSPKLPFVQSRPALSVIVTTMAAALFVTSLPYSLFASVLKTAPLNGAYFLFLLLIIVLYMVSVTFVKHLYIKRYGEWL
>NZ_CP012648.1|WP_046165249.1|1191570_1192737_+|pyridoxal-phosphate-dependent-aminotransferase
MGKYNFKTAPNRFGHHTYKWKEAEEDREVLPAWIADMDFEVLPEIQQAVHDYADHLVYGYTYASEELIKAVLDWERDEHGYAFDRDALVFIEGVVPAISTAIQAFTKEGDAVLINTPVYPPFARSVKLNNRRLIANSLIEQDSLFQIDFEQLERDIVDNEVKIYVLCNPHNPGGRVWEREVLEKIGRLCQKYGVLVVSDEIHQDLTLFGHEHQSFNTVSPDFKDFSLILSSATKTFNIAGTKNSYAVIENPSLRHQFKKRQLANNQHEISGLGFVATEAAYRYGKSWLTELKTVLEENIDFVVDYFAKEAPRLKVMKPQGTYLIWLDFSDYDLTDDQLFQLLREEAKVVLNRGSDFGQEGKSHARLNAAAPKDMVVEICKRIGAVLPK
>NZ_CP012648.1|WP_046165253.1|1203055_1203712_+|CBS-domain-containing-protein
MAVKDFMTRKVVYISPDTTVAHAADIMREQGLHRLPVIENDKLVGLVTEGTIAEASPSKATSLSIYEMNYLLNKTKIKDVMIRKVITVSQYASLEDATYLMLKNKVGILPVVDNEQVYGVITDRDIFKAFLEVSGYGEEGVRARFVTEDEVGVLEHIVHLLVEENLNISNAVNIPRKDGKVVIEVQIDGKVDLEALKTKFEDNQIHVDSIVHTEAKAL
>NZ_CP012648.1|WP_046165254.1|1203780_1205016_-|aminoacyltransferase
MTFKLLSQEEFIQHTSASSQRSFMQTVEMAELLSKRGFSTQYVGYTDPQGQVVVSAVLYSMPMTGGLHMEINCGPVSTDAQYLPPFYQALQAYAKKEGALELIIKPYETYQTFDSNGQPTSDEKVELIQQLTDLGFDFDGLQTGYPGGEPDWHYVKDLAGLTEKDLLKSFSKNGKATVKKANTFGIKLTRLERDQLSIFKDITAATSDRREYDDKPLDYYQDFYDSFGQQADFMTASLNFKDYLQNLQKDQEKLGQKIQKLQTDLENNPQSEKKQNQLRELSSQFDSFETRKAEAQELIDKYGDQDQVLAASLFIYTPQEATYLFSGSYPEFNKFYAPALLQEYVMTESIKRGIPFYNFLGIMGIFDGSDGVLRFKQNFNGFIVRKMGTFRYYPNPLKFKIIQLIKKILRR
>NZ_CP012648.1|WP_046165255.1|1205030_1206245_-|aminoacyltransferase
MFSYKIGISAQEHDDFVTAHPQANLLQSSAWAQIKDNWANERLGFYKDDHLVAVASVLIKPLPLGMTMLYIPRGPIMDYSDKELLTFVLASLKKFAKEKKALFVKFDPSLFLAESKMGGEMQDKSGTIELIQDLQQAGAVWVGRTESLDETIQPRLQANIHKEDFSEDLLSKSTRQAIRTARNKGIQIQFGGAELLDDFSGLMKKTENRKNIHLRGKDYYQKLLDTYPNHSYITLSSIDLKARLEDLQAQLTKTLKEAEKFTEKTKPGKIENNQQEQKRLQEEIDFLQDKISQGATVVPLSGTLVLEYGKTSENIYAGMDEEYRRYQPAIITWYETAKHAFERGADWQNMGGIENDLKGGLYSFKSKFNPTIEEFAGEFNLPTNPLYHLSNLAYTIRKKLRSKH
>NZ_CP012648.1|WP_046165256.1|1206244_1207054_-|sugar-phosphatase
MSIQLVAIDIDGTLLNNKKEITPEVFSAIQDAKATGIKIVIATGRPIAGVQKLLEELELNQPGNYVITFNGGLIQDTVTGQELIKETLSYDDYLDIELLGRKLGVHMHAITKDGIYTANRNIGKYTVYESNLVSMPIFYRTPEEMANKEIVKCMYIDEPEILDAAIAKLPPELTEKYTLVKSAPFYLEIVKKTVNKGAAVLHLAEKLGLSKEQTMAIGDEENDRAMLEAVGSPVVMENGKEELKKIAKYITKSNDESGVAYAIREWVLK
>NZ_CP012648.1|WP_046165257.1|1207055_1208357_-|HD-domain-containing-protein
MIEKVFRDPVHTYIHVDHQVIYDLINTKEFQRLRRIKQLGTSGYTFHGGEHSRFSHCLGAYEIARRITKIFDEKYLQTWDNHESLLVMVTALLHDVGHGAYSHSFERLFDTDHEEITRQIITSPETEINRVLTQVSPDFPEKVASVINHTHPNKQVVQLISSQIDVDRMDYLLRDSFYTGASYGQFDLTRILRVIRPVENGIAFQRNGMHAVEDYVVSRYQMYMQVYFHPASRAMEVLLQNLLKRAKFLYEDQKDFFKLTSPNLLPFFEKRFSLQDYLALDDGVMNTYFQSWMTSPDTILSDLAQRYVNRKVFKSMIFSEENEKHLDVLRQLVKQVGFEPDYYTAIHRNFDLPYDFYRPDVEKPRTQIEIIQKDGSLAELSSLSPIVQSLAGTRQGDNRFYFPKEMLTDAGLFNENSQAFLSYMKNDTFIYGE
>NZ_CP012648.1|WP_046165258.1|1208461_1208848_+|DUF1934-domain-containing-protein
MKIRMKNQIQLDGQTELIDQIYDAEWAQKGDHHYLLFKNEEDEKVVLKFHDTELTMTRFSNPKTLMRFIKDDRALVGVPTPMGIQTLMTDTQRYHLDLDKQIICLDYQLKTPDGERLFADYQMEISWL
>NZ_CP012648.1|WP_053794451.1|1209068_1211765_+|cation-translocating-P-type-ATPase
MSKEQKRQAFYTQDQDLVLQEMETSKEGLTSSEAAKRLSEYGRNELDEGEKKSLLVKFIEQFKDLMIIILLVAAVLSVVTSGGEDIADAIIILAVVIINAAFGVYQEGKAEEAIEALKSMSSPAARVLRDGHVAEVDSKELVPGDIVILEAGDVVPADLRLFEANSLKIEEAALTGESVPVEKDLSVELAEDAGIGDRVNMAFQNSNVTYGRGIGVVVNTGMYTEVGHIAGMLQNADETDTPLKQNLNNLSKVLTYAILVIAAVTFVVGVFIQGKDPLGELMTSVALAVAAIPEGLPAIVTIVLALGTQVLAKRNSIVRKLPAVETLGSTEIIASDKTGTLTMNKMTVEKVFYDAVLHDSSDDIELGLEMPLLRSVVLANDTKIDAEGNLIGDPTETAFIQYALDKGYDVKGFLEQYPRVAELPFDSDRKLMSTVHPLPDGKFLVTVKGAPDQLLKRCVSRDKAGDIAAIDDATSHLIKSNNSEMAHQALRVLAGAYKIIDSIPENLTSEELENNLIFTGLIGMIDPERAEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGIIDENDSEDHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQNQGKVVAMTGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIIAVEEGRKVFSNIQKTIQYLLSANTAEVLTIFLATLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGVMTHKPRGRKSSFFSGGVMSSIIYQGLLQGALVLAVYGYAITNPVHIGDVKAIHADALTMAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLAATIVIDPLESIFHVTKLDLSQWAVVLLGSFSMIIIVEIVKFVQRKMGLDKNAI
>NZ_CP012648.1|WP_053794452.1|1212312_1213857_+|peptide-chain-release-factor-3
MNLQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEVLGIASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDDRFASLEDGDKLFGSNPFYEQVKEDIELLNEAGNEFSEEAILSGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGEIVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRIGKSAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSAKNVMKQKSFHKGIEQLVQEGAIQLYTNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWISPDDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVKLEEKM
>NZ_CP012648.1|WP_008809542.1|1214171_1214420_+|hypothetical-protein
MDNEEKEIIWKMPFNPLKDKAAKEYMIKENAEMQLSYNITEQIGGQLKAGFTLLDIYEDTNGSGRLHELNIKTYIAIKSVKR
>NZ_CP012648.1|WP_008809541.1|1214451_1215198_+|CPBP-family-intramembrane-metalloprotease
MSRKKAIFLYLLGTLGQIWLISIIVFVLRHLGMVVDYRTPMGMLAIGIGGLSTALWGTIIAVRYKKYSTKKILKDFFAIKQNRGSYLFAIVFLFLDFCYVAFDGELAFNTWYIPIILFLKAILFGGIEEVGWRYVFQPIMMERHSYISSTIFTFVPWGIWHFSYFYIEGTLPQVQALGFLLGLLTNCFILSALFIKTNSLWICVMTHSVINVFSQLAVGGNQNISYACRIIIIVMATVLSIREQNKND

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Crispr_ID: NZ_CP012648_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012648_4

1904979-1905608

Orphan

Consensus_repeat	Method
TACNGANGCACTCGTNGA	CRT

17 spacers

The CRISPR arrays of NZ_CP012648_4

>merge|NZ_CP012648|4|1904979-1905608|CRT
TAATGAGGCACTGGTCGATGCGGACTCACTTGCAGATACTGATGCACTGGTTGAGGTTGACTCGCTTGCCGATACAGATGCACTCGTGGAAGCTGATTCGCTCGAACTTACCGATGCGCTCGTGGAGGCTGATTCGCTCGAACTTACGGATGCACTCGTGGATGCGGACTCACTCGCAGATACAGACGCACTCGTTGAAGCTGATTCGCTCGCTGATACTGAGGCACTCGTGGAGGCCGATTCACTCGCACTTACGAACGCACTCGTGGATGCAGACTCGCTTGCAGAAACTGACGCACTCGTGGAAGCGGATGTGCTTGCACTTACTGACGCACTCGTTGAAGCCGAAGTACTTGCGCTTACGGACGCGCTGGTTGACGCAGACGTGCTGGCGGATACCGACGCACTCGTAGACGCGGACGTACTTGCAGATACCGACGCACTCGTCGATGCGGACGTACTTGCGCTTACGGACGCGCTGGTTGACGCAGACGTGCTTGCGGATACTGACGCACTCGTAGACGCGGACTCACTGGCAGAAACTGACGCACTCGTAGACGCGGACTCACTGGCAGAAACTGACGCACTCGTTGAAGCCGAAGTACTTGCACTTACGGACGCACTCGTTGA

>NZ_CP012648|4|1|1904979-1905608|CRT
TAATGAGGCACTGGTCGA	TGCGGACTCACTTGCAGA
TACTGATGCACTGGTTGA	GGTTGACTCGCTTGCCGA
TACAGATGCACTCGTGGA	AGCTGATTCGCTCGAACT
TACCGATGCGCTCGTGGA	GGCTGATTCGCTCGAACT
TACGGATGCACTCGTGGA	TGCGGACTCACTCGCAGA
TACAGACGCACTCGTTGA	AGCTGATTCGCTCGCTGA
TACTGAGGCACTCGTGGA	GGCCGATTCACTCGCACT
TACGAACGCACTCGTGGA	TGCAGACTCGCTTGCAGA
AACTGACGCACTCGTGGA	AGCGGATGTGCTTGCACT
TACTGACGCACTCGTTGA	AGCCGAAGTACTTGCGCT
TACGGACGCGCTGGTTGA	CGCAGACGTGCTGGCGGA
TACCGACGCACTCGTAGA	CGCGGACGTACTTGCAGA
TACCGACGCACTCGTCGA	TGCGGACGTACTTGCGCT
TACGGACGCGCTGGTTGA	CGCAGACGTGCTTGCGGA
TACTGACGCACTCGTAGA	CGCGGACTCACTGGCAGA
AACTGACGCACTCGTAGA	CGCGGACTCACTGGCAGA
AACTGACGCACTCGTTGA	AGCCGAAGTACTTGCACT
TACGGACGCACTCGTTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012648.1\|WP_053794667.1\|1914493_1915165_-\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_CP012648.1\|WP_053794669.1\|1915922_1916789_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|214678
NZ_CP012648.1\|WP_046165700.1\|1889199_1890720_-\|accessory-Sec-system-glycosyltransferase-GtfA	unknown	unknown	gnl\|CDD\|131964
NZ_CP012648.1\|WP_045634942.1\|1887688_1887871_-\|accessory-secretory-system-protein-Asp4	unknown	unknown	gnl\|CDD\|319060
NZ_CP012648.1\|WP_172672776.1\|1909582_1910908_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP012648.1\|WP_046165704.1\|1895101_1896682_-\|accessory-Sec-system-protein-Asp1	unknown	unknown	gnl\|CDD\|293598
NZ_CP012648.1\|WP_053794912.1\|1908663_1909527_-\|pyridoxamine-kinase	unknown	unknown	gnl\|CDD\|180840
NZ_CP012648.1\|WP_053794666.1\|1912664_1914404_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|182732
NZ_CP012648.1\|WP_053794665.1\|1910920_1912663_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP012648.1\|WP_046165705.1\|1896690_1897914_-\|accessory-Sec-system-protein-translocase-subunit-SecY2	unknown	unknown	gnl\|CDD\|237095
NZ_CP012648.1\|WP_053794662.1\|1897945_1898950_-\|sugar-transferase	unknown	unknown	gnl\|CDD\|236626
NZ_CP012648.1\|WP_046165699.1\|1887863_1889216_-\|accessory-Sec-system-glycosylation-chaperone-GtfB	unknown	unknown	gnl\|CDD\|274351
NZ_CP012648.1\|WP_046165701.1\|1890732_1893114_-\|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl\|CDD\|163426
NZ_CP012648.1\|WP_046165702.1\|1893106_1893586_-\|accessory-Sec-system-protein-Asp3	unknown	unknown	gnl\|CDD\|163423
NZ_CP012648.1\|WP_053794670.1\|1916800_1917415_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012648.1\|WP_053794671.1\|1917600_1918512_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|224398
NZ_CP012648.1\|WP_053794668.1\|1915209_1915842_-\|copper-homeostasis-protein-CutC	unknown	unknown	gnl\|CDD\|225684
NZ_CP012648.1\|WP_045634941.1\|1887465_1887687_-\|accessory-secretory-protein-Asp5	unknown	unknown	gnl\|CDD\|374926
NZ_CP012648.1\|WP_053794663.1\|1908143_1908674_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227064
NZ_CP012648.1\|WP_053794661.1\|1893582_1895112_-\|accessory-Sec-system-protein-Asp2	unknown	unknown	gnl\|CDD\|274739

Protein	Function_ID	Function_description	E-value
NZ_CP012648.1\|WP_053794667.1\|1914493_1915165_-\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	1.31569e-18
NZ_CP012648.1\|WP_053794669.1\|1915922_1916789_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|214678	smart00470, ParB, ParB-like nuclease domain. Plasmid RK2 ParB preferentially cleaves single-stranded DNA. ParB also nicks supercoiled plasmid DNA preferably at sites with potential single-stranded character, like AT-rich regions and sequences that can form cruciform structures. ParB also exhibits 5-->3 exonuclease activity.	0.000637865
NZ_CP012648.1\|WP_046165700.1\|1889199_1890720_-\|accessory-Sec-system-glycosyltransferase-GtfA	gnl\|CDD\|131964	TIGR02918, lipopolysaccharide_biosynthesis_protein, accessory Sec system glycosylation protein GtfA. Members of this protein family are found only in Gram-positive bacteria of the Firmicutes lineage, including several species of Staphylococcus, Streptococcus, and Lactobacillus. Members are associated with glycosylation of serine-rich glycoproteins exported by the accessory Sec system. [Protein fate, Protein modification and repair].	0
NZ_CP012648.1\|WP_045634942.1\|1887688_1887871_-\|accessory-secretory-system-protein-Asp4	gnl\|CDD\|319060	pfam16996, Asp4, Accessory secretory protein Sec Asp4. Asp4 and Asp5 are putative accessory components of the SecY2 channel of the SecA2-SecY2 mediated export system, but they are not present in all SecA2-SecY2 systems. This family of Asp4 is found in Firmicutes.	6.91881e-11
NZ_CP012648.1\|WP_172672776.1\|1909582_1910908_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	4.61307e-90
NZ_CP012648.1\|WP_046165704.1\|1895101_1896682_-\|accessory-Sec-system-protein-Asp1	gnl\|CDD\|293598	pfam16993, Asp1, Accessory Sec system protein Asp1. Asp1, along with SecY2, SecA2, and other proteins forms part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. Asp1 is predicted to be cytosolic.	0
NZ_CP012648.1\|WP_053794912.1\|1908663_1909527_-\|pyridoxamine-kinase	gnl\|CDD\|180840	PRK07105, PRK07105, pyridoxamine kinase; Validated.	7.12657e-137
NZ_CP012648.1\|WP_053794666.1\|1912664_1914404_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|182732	PRK10789, PRK10789, SmdA family multidrug ABC transporter permease/ATP-binding protein.	3.25285e-179
NZ_CP012648.1\|WP_053794665.1\|1910920_1912663_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.57808e-173
NZ_CP012648.1\|WP_046165705.1\|1896690_1897914_-\|accessory-Sec-system-protein-translocase-subunit-SecY2	gnl\|CDD\|237095	PRK12417, secY, preprotein translocase subunit SecY; Reviewed.	4.69611e-174
NZ_CP012648.1\|WP_053794662.1\|1897945_1898950_-\|sugar-transferase	gnl\|CDD\|236626	PRK09814, PRK09814, sugar transferase.	2.74832e-157
NZ_CP012648.1\|WP_046165699.1\|1887863_1889216_-\|accessory-Sec-system-glycosylation-chaperone-GtfB	gnl\|CDD\|274351	TIGR02919, conserved_hypothetical_protein, accessory Sec system glycosyltransferase GtfB. Members of this protein family are found only in Gram-positive bacteria of the Firmicutes lineage, including several species of Staphylococcus, Streptococcus, and Lactobacillus. [Protein fate, Protein modification and repair].	0
NZ_CP012648.1\|WP_046165701.1\|1890732_1893114_-\|accessory-Sec-system-translocase-SecA2	gnl\|CDD\|163426	TIGR03714, Protein_translocase_subunit_SecA_2, accessory Sec system translocase SecA2. Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP012648.1\|WP_046165702.1\|1893106_1893586_-\|accessory-Sec-system-protein-Asp3	gnl\|CDD\|163423	TIGR03711, acc_sec_asp3, accessory Sec system protein Asp3. This protein is designated Asp3 because, along with SecY2, SecA2, and other proteins it is part of the accessory Sec system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	5.41123e-62
NZ_CP012648.1\|WP_053794671.1\|1917600_1918512_-\|DNA-binding-protein-WhiA	gnl\|CDD\|224398	COG1481, COG1481, Uncharacterized protein conserved in bacteria [Function unknown].	2.5803e-131
NZ_CP012648.1\|WP_053794668.1\|1915209_1915842_-\|copper-homeostasis-protein-CutC	gnl\|CDD\|225684	COG3142, CutC, Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism].	1.30686e-93
NZ_CP012648.1\|WP_045634941.1\|1887465_1887687_-\|accessory-secretory-protein-Asp5	gnl\|CDD\|374926	pfam17000, Asp5, Accessory secretory protein Sec, Asp5. Asp4 and Asp5 are putative accessory components of the SecY2 channel of the SecA2-SecY2 mediated export system, but they are not present in all SecA2-SecY2 systems. This family of Asp5 is found in Firmicutes.	3.09449e-12
NZ_CP012648.1\|WP_053794663.1\|1908143_1908674_-\|ECF-transporter-S-component	gnl\|CDD\|227064	COG4720, COG4720, Predicted membrane protein [Function unknown].	1.42962e-20
NZ_CP012648.1\|WP_053794661.1\|1893582_1895112_-\|accessory-Sec-system-protein-Asp2	gnl\|CDD\|274739	TIGR03712, acc_sec_asp2, accessory Sec system protein Asp2. This protein is designated Asp2 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0

>NZ_CP012648.1|WP_053794662.1|1897945_1898950_-|sugar-transferase
MKVNITNLYGMSGQSTALIAQNDVTKLAKQLGFNELSFYFYDIYSDSQSELSRRLDGIMASVGYGDVVIYQSPTWNGREFDQAFISKLKILQAKLITFIHDVPPLMFPSNYYLMQEYIDMYNQSDVVIVPSEQMRDKLLAEGLTVDKILIQRMWDHPYDLPLHQPQFAPKLYFAGSVERFPHLSNWSYAMPLEIFSPEEESNPEANVSYRGWVSRPELLLELSKGGLGLVWGVEENPADEPEYYGLNISHKSATYLAAGIPVIVPSYLSNAELIRERGLGFVVDSLEEASRIVENLTAEEYQAMVERVRKFSYLLKEGYFSKKVLIDAVMAVLS
>NZ_CP012648.1|WP_046165705.1|1896690_1897914_-|accessory-Sec-system-protein-translocase-subunit-SecY2
MKSFFKPLILKKFLWTLLFVFIYILGSKLTLPFVDVSNIAKLNGDSVTLNYAAALMGGNLRSMSFFSIGLAPWMSSILIWQMFTVSKRLGLNKLSMESQEKRRMLLTLAIALIQSLGLVLNLPLKTVAGVGQGTIVFLDTLILIAGTYFLIWLTDLNSSMGLGGSIMIVMVSMISYIPQDIWLSIQELKISPLILAVVGLLSLCFLYLAVLVERAKYRIPINKINIHNRFKKYSYLDIRVNAAGGLPIMYAMTLVSIPQYFLMLVLFFQPNNRLVKEWILSLAMGGIPWFILYLLTIFILAWAFAFINVNSDQIAERMQRSGEYIENLYPGEATRRYIHKIVGYFAFVGALYLVLVAGLPMLLILLDIRYMRLGMIPGMFMIFIGMVFSIKDEVDTLTLNDRYHSLF
>NZ_CP012648.1|WP_046165704.1|1895101_1896682_-|accessory-Sec-system-protein-Asp1
MYYFIPSWSGSGKRVWHRDIIPWYRSMQRLEFDDTIHQIRIFHSENLPVKLLLQAYMPHARYFLHRQDIFETEYYSVFDEIQAVESNDMQVLQIKDLEWEDDCEFIYTPFLIIVRRQGQLYAHVEFGVEGFISFIKFFKDDQLEKLNIFDDRGFVSSIVYYEDGQEVCQDYLNPNGDWRIREYLKFENSHVVVNPVFSRDFDKLEYEYMPDLILEKLGYYISHNVEEDSRFVVAAQPFANQGVLDLLPQHSHSILSFFHERNQASNIENLKADLEYSNLVLTDRMDFKETLQNHFPLQTEKIHYLSPFDTRLQLGKSQQRHESKIFYQIDLNELLNDYAIFKVLFYVAQHPDTELVIGVYNAWQEGIKQVENKVEELISDYLDLKDFIKKSYKNSQAENPLPENQELEYRFRIKNITDELSLIQELDDTRLIIDLSQQPNLYTQIAGISAGIPQINLVASDYVTHLQNGYILDSISQLAVAADYYLQGLKNWNQALIYSIEKIKLNTGHQVIKRWEKWLKEAIDEK
>NZ_CP012648.1|WP_053794661.1|1893582_1895112_-|accessory-Sec-system-protein-Asp2
MKNKLKILQIGSINWRKEVVIPDNIDWYYFFPHSQLAIKKVMEMEKINHFSAIIVDDLDLIPDLFLIESRIIPYTIFYSKKQQAIQEPIAFFLKRYCAQQIDLSDRPNLLRKLSKALFRGQYGDKMTPLDMVVSPGFKGRICHNGYENLELEGNFGSDFRPIVSWKYNIVASKKNPVEIWLEYEKDLSCELRLRIYNIQEGSAADLVRESVFSETDMQEAIVLDNDFTSFLGITLEARGFGTLKIGAFHQRLTRYEFGKFVLGGEILKDSHRQEINYFFYPGDFKPPLVVYFSGYRRAEGFEGFGMMRGLGCPFLLISDQRLDGGVFYLGSDELEESIRRIIQEHMELLGFSERELILSGISMGTYGAAYYGADFSPRAIILCKPLANLGTIAQRGRLRLPEVFPMALDILHRHTGGKGRENVIELDNRYWKKFKNADFRRTIFGLAYMKEEDYDPTAYEDLVQYLYPTETQLMSNGLSGRHNDDSTMVINWFMNYHRIILEKEFGRKK
>NZ_CP012648.1|WP_046165702.1|1893106_1893586_-|accessory-Sec-system-protein-Asp3
MKIQKHKEIYWGELRGASISKTRKDFTYLYGSTIIFHSPDQVYFENKLMASGQTIHEWSSSWNYQGDRQVPSLPLLKRGRSYSLTRDMTSYPSESVFLKLIFFDRYNREVSNYVERSNKMTFTYPKDAYSYKVQLLSAGVESFEFRCLRIEEILKESNG
>NZ_CP012648.1|WP_046165701.1|1890732_1893114_-|accessory-Sec-system-translocase-SecA2
MVNNFFHIRRLKKILAKVKSFEKEMACLSDLDLQKKTDEFKKRLADGENLDQLLPEAYAVVREADKRILGLFPYDVQVMGAIVLHEGNIAEMATGEGKTLTATMPLYLNALSGQGAMLVTPNSYLALRDAKEMGPVYRFLGLTIETAVRADETKPLETKEKRRIYQADILYTTNSALGFDYLIENLAENKKNQFLREFNYVIIDEIDSILLDSAQTPLIISGAPRVQSNFYDMMDTLVQTLYEDEDYCYDDEKNEVWLTQKGIRAAESFLGLNHLFSKENQELVRHLNLALRAHMVYKKDQDYVVRQSENEAEVVLLDRSTGRLMELTRLQGGQHQAIEAKEHVKLTQETRAMASITYQNLFKLFRKLSGMTGTGKVVESEFLETYSMSVVKIPTNCPVIRRDYPDQIYQTLPEKVFASLDEVKHYHAKGNPLLIFTGSVEMSEIYSSLLLREGIAHNLLNANNAAREAQMIAESGQLGAVTVATSMAGRGTDIKLGPGVADLGGLVVIGTERMENHRIDLQIRGRSGRQGDPGISKFFISLEDDLLKKWGPDWIKNFYRDYSPEDLKNNPILLKQRRFKKLVSKAQKASEGNAKLSRRLTLEYAQSMKIQRELTYAERNRLLEDTNEMEEEINRVLDYVIQQVAYEQSFENRADFYRFILHHFSNRAERIPQEFDIHSPKEVSHLLQAIAEQELLAKKSYLKSDKLYSQFQRLAILKAIDENWVEQVDYLQQLKSALSGFHTSNKNPIVEYYQEAYDGFEYMKERMKHQIVKNLLMSELALNPKGEVVMYFP
>NZ_CP012648.1|WP_046165700.1|1889199_1890720_-|accessory-Sec-system-glycosyltransferase-GtfA
MTVYNINLGIGWASSGVEYAQAYRAQILRRIQQPAKFIFMDMILADNIQHLTENIGFLDGEIIWLYNYFTDIKIAPTTVTLDQVLAQVAGQPERSEREGKIVRYFYPQDDQFITCYLRQEDQDFVEHVEYVSRGRLIRKDYFSYVRYASEYFAPHNDAATLYQRRFYHEDGSVAYDMLIEDGQEKLYRFPDRIFYSKAELVRYFLQCLQLQADDVVILDRETGIGQVVFEESQKAKLGVVVHAEHFSENASSDDYILWNNFYDYQFTNADKVDFFIVATEAQKRILEQQFQHYSDKQPQIATIPVGSLDQLTYPKEPRKPYSMITASRLATEKHIDWLVAVTVQAHAQLPELTLDIYGKGSEEDKLRRRIEEAGAQDYIRLKGHADLSQIYAGYELYLTASTSEGFGLTLMEAVGSGLPLIGFDVRYGNQTFIDDGKNGYLLPVSSNHVEDQIIAAFVEKIIALFSQGRQQEMSQHSYQVAENYLTSRVEAAWTQLLKEVRDDSAL
>NZ_CP012648.1|WP_046165699.1|1887863_1889216_-|accessory-Sec-system-glycosylation-chaperone-GtfB
MIQLFDYYNQETQDLHDSLLAAGYACPTIVIEANGFLPDDMISPYTYFLGDEEGVDHPLFFNQVPVPPFWEITGDHQAARVSDMGEERARIHYASQARGRLVKQVDWLDKKGQLRLSERYNKQGRCFAKTAYKSGQEAFNTTYYSTDGQERIVENHVTGDIILTLDQEPLRIFKSRVDFIRFFLERLDLDLDHILFNSLAYSFLVSHSLTGRAGQDILFWQEPLYDELPGNMQLILDNSQLRTQTIVIPDLATYEKAMSLAAADQQQKFLHLGYHYDFKRDNYLRKDALILTHSDQIEGLEALVQSLPQLVFRIAALTEMSPKLLSMLSYKNVVLYQNASLKQIEQLYLESDIYLDINHGGQVLQAVRKAFENNLLILGFEQTLHDRHYIAQQHIFDSSQPAQLASILEEALSGVEQMRSALQAQGRHANDVPVSLYQETLQSLLGGQHG
>NZ_CP012648.1|WP_045634942.1|1887688_1887871_-|accessory-secretory-system-protein-Asp4
MAKKDLFHKDIEGRLDELKHGKPKKEKASLGENLNKIFVIALGLMILIGLIFTLIGALRK
>NZ_CP012648.1|WP_045634941.1|1887465_1887687_-|accessory-secretory-protein-Asp5
MQKLLLILTILLALILITLVISLPRENQQFFSETRSTIGKSGYWETNFFKKIILLIVSILLFLTLIFYMIQTA
>NZ_CP012648.1|WP_053794663.1|1908143_1908674_-|ECF-transporter-S-component
MKNNKLTTRELVELSLFSALIALSIQFFRIPVGPQFIHFGNALVVVATLIYGVRKGALVATVGLGAFDILNGYASVVWITILEALVVILVVHFVYEAMPENRERLVIVGFAAALTKIVLNLFKYTLIGMLGNLTLGASLNLALVKIVGTFGSSLATVIAVPILYPIFKKISETIRK
>NZ_CP012648.1|WP_053794912.1|1908663_1909527_-|pyridoxamine-kinase
MTKPKRIILASDISGLGKVAVTAALPLFAVCQLEVSVLPTVLLSSHTGGFPKVYIDDYTVGMQAFLKQWQSLEIGISALVTGYLRSSQQIASLIDFLEHENIPLIVDPIMGDNGKLYKGFDDHYISSMRTLCQKADLILPNLTEACFLADLPYQDNDLTEQFLKSLAQRLSELGAKKILLTGLPLSHDQIGVAYFDKAEGVFSLYKGKRFQQQFFGTGDMLTGLVAAAFVQGLDLQKCLPVFINFIEKSLATTLDCHFDLRYGVYYQPHLGDLFKEFKRLLEVSNEK
>NZ_CP012648.1|WP_172672776.1|1909582_1910908_+|PLP-dependent-aminotransferase-family-protein
MSYNMKKSNLYGDSCMLKTKYQEISDHLIEQIKNGQLKKGDKVPSIRLLSKSYHCSKDTVQKALLDLSYQKYIYAVPKSGYYVLEQAPGENNDLELPLRNDRHQVYEDFRICLNETLIGRENYLFNYYSQQEGLEDLRQSVKNLLLESAIYPTLDKIALTSGTQQALYILSQIDFPNHDDTILVEQPTYHRINDLLKAQNLKYKTIERSPKGIDLLELENIFRSGNIKFFYTIPRFHYPLGHTYSRQEKEEILRLAKLYQVFLIEDDYLADFDNKSELSFHYLDDSDSVIYIKSFSTSLFPALRITALLLPDSVKKPFIAFKSILDYDSNLIMQKALSLYIDNQMFQKNRQALLRLQEEEKENAQHLLEKSGLGLPYLLTPGGVLLDLKTLTSISSLKHSGLPLDFFESAYIDPCPYRYVKIRYQDLEASIEGLKKYVKKA
>NZ_CP012648.1|WP_053794665.1|1910920_1912663_-|ABC-transporter-ATP-binding-protein
MKKQSTFQRLLSYMLAYKWLTLSAFAFVFLTTLVTTALPLLARTYIDQFISSGQAAAGFYLLAIYYGLFILRVLLTFLGQYSFAKVAHSIVRDLRQEAFANIQKLRMAYFDQTPAGAIVSRLTNDTQAVADMFSSIFSSFLSSIFILVVTAATMFALDWRLALLILLFLPIMLASILLYQKLSTGLLKQVRSKLSDLNVKLSETIEGMRIVQAFSQEKRLIDEFEEINQEHLNYTNRYLDVNSLLLRPAMSLLKILAYGVILTYFGLTWQSAGITAGIMYAFIQYANQLFNPLIEVMQNYSVLQTSMISAERVFEVIDRRDYEPIQKNKDLKIQKGDIEFRNVSFSYDGKRDILKHISFKVKQGETIAFVGSTGSGKSSIINLFLRFYEFERGQILIDGHDIKDYSQAELRRHIGLVLQDPFLYHGTVASNIQMYQEGLSLQDIEEAAKFVDAHDFIKQLPLTYDAPVTERGAAFSSGQRQLLAFARTVATKPKILILDEATANIDSETEELIQASLKKMRQGRTTIAIAHRLSTIQDANCIYVLDKGQIIESGSHEELLAQNGTYKKMYQLQAGMLEKA
>NZ_CP012648.1|WP_053794666.1|1912664_1914404_-|ATP-binding-cassette-domain-containing-protein
MKLLKKLSWFFKLEKWPYITGVLALSLVSLLNLLPPRVIGEVIDQIASRDLTNLELAYQLFLLVLSALAMYALRFVWRKYILGTANRLGRILRYRLFEHFTRMSSSFYQTYRTGDLMAHATNDINAVVGVAGGGVMSAVDASITALVTVLTMFFVLDWRLTLIAILPLPFMAWGTSLIGRKNHESFKAAQEAFSDLNNKVQESFSGIKVTKSFGYQDAETAAFASINQDVFKKNILAAKYNALFDPMVLIFVGLSYLLTLIFGGLFISQGQLTVGELVTFITYLDMLVWPLQAMGYLFNISQRGTVSYERIESLLAQESDVIEVASAITDIKNGRLDYSIQEFAYDDRPTLRDIHFSIEQGQTLGIVGVTGSGKTTLLRLLLREQDIQEGSIYLAGHDIRDYSLSALRSLIGYVPQDQILFATSIRDNIRFGNPSLSDEDVIAVTKLCGIYEDIMQMPDGFDTLVGERGVSLSGGQKQRLAMCRALILNPDILILDDSLSAVDAKTEHLILDNLKRERSGKTTLITAHRLSAVVHADLILVLDQGRIIESGSHQELLTQDGWYATTYQNQQLAESLEEV
>NZ_CP012648.1|WP_053794667.1|1914493_1915165_-|MmcQ/YjbR-family-DNA-binding-protein
MFELFEKYKANSDKLVQYGFIEKEGIYRISRKVMSGDFQMLINVEDSSVSFQLFDCETGDEYRQVHMESMAGEFVGQVRQACLDVLLDIRRHCFDEIGFLYEQSQRLVAHVSERYQGSLEYLWAKSSRKSSTQAAVFRHEGTKKWYGAFLTTDWSKFDSGRSGAIEVLNVKNNQVSERIQEKGIYPAFHMNKKYWLSLPLDDTLTDQELFSLLEESFLLTKKK
>NZ_CP012648.1|WP_053794668.1|1915209_1915842_-|copper-homeostasis-protein-CutC
MLYEFCAENVTLLEKAMQAGARRIELCDNLTVGGTTPSYGVIRAAVDLAKPYETSIMTMIRPRGGDFVYTDLEVAIMIEDIKKAREAGSQGVVYGLLTRENELDTENLESLLAVSKDLEVVFHMAFDSIPRDKQFEALDWLAEHGVKRILTHGGSASETIQEHFAWLKELVAYADKRIQILPGGGITTQNRGEIVAELGVDQLHGTKVVF
>NZ_CP012648.1|WP_053794669.1|1915922_1916789_-|GNAT-family-N-acetyltransferase
MTMVNLAQPDVILINSNLRLRAYDGHYQVAFSWYQDPDLVYFVDGKKGSYSLEKIKKMYEVLSQRGELYFIEVKQDDSWLPIGDVTFSENDLPIVIGVETYRSIGIGREVIGALIERARSLSYRQLRVQDIYGFNLSSKKLFTSFGFYPYEETDLGHRYVLDLVLPFSEIQPSQFFLSEKKLEEIATWFDQEELKPLPVKRWKGEWFLTDGHSRAFTAYLRGRSEIPVYFDRDDINLKFYSNCIRVCQEKSILSIADLKDRILSEEAYQTEWLDWCKNSFESMNDMDS
>NZ_CP012648.1|WP_053794670.1|1916800_1917415_-|hypothetical-protein
MKKIIKRTVVGLLVLLFGLILILVPSSIQSSDQLKNVESTISLSSMVESGLENATVGTNGLSTEITINSKQFNQLLKSFLTDNQSQELLESAYSIEGDKLRLQLPIKILGVDSKLDLRFYAAYENHTLRFDLASSRLGNLPVPKAIVASILQNRLKDQSSNLAMEQETILVSLPESQFKITGLNIQDNTAKVKLTMNMSGLLGQ
>NZ_CP012648.1|WP_053794671.1|1917600_1918512_-|DNA-binding-protein-WhiA
MSFTVKVKEELLGLGTKSKSELAAIMKMSGSLGIASQGLTLSITTENAKIARHIYELLLSFYQVKSDIRHHQKTNLRKNRVYTVFLDEKVEDILSDLHLADAFFGIQEGIDPLILSDDEASRAYLRGAFLSNGSMRDPESGKYQLEIVSVYLDHAQGLASLMQRFLLDAKTIERKKGAVTYLQRAEDIMDFLIVVGAMEAMAEFETVKILRETRNDINRANNAETANIARTVTASMKTINNIVKIMETSGLESLPIDLQEVAHLRVNHPDYSIQQLADSLSKPLTKSGVNHRLRKINKIADDL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP012648_4	4.9\|1905285\|18\|NZ_CP012648\|CRT	1905285-1905302	18	NZ_CP012648.1	1905825-1905842	0	1.0
NZ_CP012648_4	4.9\|1905285\|18\|NZ_CP012648\|CRT	1905285-1905302	18	NZ_CP012648.1	1905933-1905950	0	1.0
NZ_CP012648_4	4.12\|1905393\|18\|NZ_CP012648\|CRT	1905393-1905410	18	NZ_CP012648.1	1901937-1901954	0	1.0
NZ_CP012648_4	4.12\|1905393\|18\|NZ_CP012648\|CRT	1905393-1905410	18	NZ_CP012648.1	1902585-1902602	0	1.0
NZ_CP012648_4	4.12\|1905393\|18\|NZ_CP012648\|CRT	1905393-1905410	18	NZ_CP012648.1	1903449-1903466	0	1.0
NZ_CP012648_4	4.12\|1905393\|18\|NZ_CP012648\|CRT	1905393-1905410	18	NZ_CP012648.1	1903665-1903682	0	1.0
NZ_CP012648_4	4.12\|1905393\|18\|NZ_CP012648\|CRT	1905393-1905410	18	NZ_CP012648.1	1904097-1904114	0	1.0
NZ_CP012648_4	4.15\|1905501\|18\|NZ_CP012648\|CRT	1905501-1905518	18	NZ_CP012648.1	1904601-1904618	0	1.0
NZ_CP012648_4	4.16\|1905537\|18\|NZ_CP012648\|CRT	1905537-1905554	18	NZ_CP012648.1	1904601-1904618	0	1.0
NZ_CP012648_4	4.17\|1905573\|18\|NZ_CP012648\|CRT	1905573-1905590	18	NZ_CP012648.1	1905609-1905626	0	1.0
NZ_CP012648_4	4.3\|1905069\|18\|NZ_CP012648\|CRT	1905069-1905086	18	NZ_CP012648.1	1903845-1903862	1	0.944
NZ_CP012648_4	4.4\|1905105\|18\|NZ_CP012648\|CRT	1905105-1905122	18	NZ_CP012648.1	1904961-1904978	1	0.944
NZ_CP012648_4	4.6\|1905177\|18\|NZ_CP012648\|CRT	1905177-1905194	18	NZ_CP012648.1	1904169-1904186	1	0.944
NZ_CP012648_4	4.7\|1905213\|18\|NZ_CP012648\|CRT	1905213-1905230	18	NZ_CP012648.1	1901769-1901786	1	0.944
NZ_CP012648_4	4.7\|1905213\|18\|NZ_CP012648\|CRT	1905213-1905230	18	NZ_CP012648.1	1902729-1902746	1	0.944
NZ_CP012648_4	4.7\|1905213\|18\|NZ_CP012648\|CRT	1905213-1905230	18	NZ_CP012648.1	1903521-1903538	1	0.944
NZ_CP012648_4	4.7\|1905213\|18\|NZ_CP012648\|CRT	1905213-1905230	18	NZ_CP012648.1	1903917-1903934	1	0.944
NZ_CP012648_4	4.7\|1905213\|18\|NZ_CP012648\|CRT	1905213-1905230	18	NZ_CP012648.1	1903989-1904006	1	0.944
NZ_CP012648_4	4.7\|1905213\|18\|NZ_CP012648\|CRT	1905213-1905230	18	NZ_CP012648.1	1904457-1904474	1	0.944
NZ_CP012648_4	4.10\|1905321\|18\|NZ_CP012648\|CRT	1905321-1905338	18	NZ_CP012648.1	1905609-1905626	1	0.944
NZ_CP012648_4	4.12\|1905393\|18\|NZ_CP012648\|CRT	1905393-1905410	18	NZ_CP012648.1	1901805-1901822	1	0.944
NZ_CP012648_4	4.12\|1905393\|18\|NZ_CP012648\|CRT	1905393-1905410	18	NZ_CP012648.1	1902369-1902386	1	0.944
NZ_CP012648_4	4.12\|1905393\|18\|NZ_CP012648\|CRT	1905393-1905410	18	NZ_CP012648.1	1904925-1904942	1	0.944
NZ_CP012648_4	4.1\|1904997\|18\|NZ_CP012648\|CRT	1904997-1905014	18	NZ_CP012648.1	1903701-1903718	2	0.889
NZ_CP012648_4	4.3\|1905069\|18\|NZ_CP012648\|CRT	1905069-1905086	18	NZ_CP012648.1	1902081-1902098	2	0.889
NZ_CP012648_4	4.3\|1905069\|18\|NZ_CP012648\|CRT	1905069-1905086	18	NZ_CP012648.1	1902333-1902350	2	0.889
NZ_CP012648_4	4.3\|1905069\|18\|NZ_CP012648\|CRT	1905069-1905086	18	NZ_CP012648.1	1902765-1902782	2	0.889
NZ_CP012648_4	4.3\|1905069\|18\|NZ_CP012648\|CRT	1905069-1905086	18	NZ_CP012648.1	1903197-1903214	2	0.889
NZ_CP012648_4	4.3\|1905069\|18\|NZ_CP012648\|CRT	1905069-1905086	18	NZ_CP012648.1	1904853-1904870	2	0.889
NZ_CP012648_4	4.4\|1905105\|18\|NZ_CP012648\|CRT	1905105-1905122	18	NZ_CP012648.1	1901769-1901786	2	0.889
NZ_CP012648_4	4.4\|1905105\|18\|NZ_CP012648\|CRT	1905105-1905122	18	NZ_CP012648.1	1902729-1902746	2	0.889
NZ_CP012648_4	4.4\|1905105\|18\|NZ_CP012648\|CRT	1905105-1905122	18	NZ_CP012648.1	1903521-1903538	2	0.889
NZ_CP012648_4	4.4\|1905105\|18\|NZ_CP012648\|CRT	1905105-1905122	18	NZ_CP012648.1	1903917-1903934	2	0.889
NZ_CP012648_4	4.4\|1905105\|18\|NZ_CP012648\|CRT	1905105-1905122	18	NZ_CP012648.1	1903989-1904006	2	0.889
NZ_CP012648_4	4.5\|1905141\|18\|NZ_CP012648\|CRT	1905141-1905158	18	NZ_CP012648.1	1902873-1902890	2	0.889
NZ_CP012648_4	4.5\|1905141\|18\|NZ_CP012648\|CRT	1905141-1905158	18	NZ_CP012648.1	1903305-1903322	2	0.889
NZ_CP012648_4	4.6\|1905177\|18\|NZ_CP012648\|CRT	1905177-1905194	18	NZ_CP012648.1	1901697-1901714	2	0.889
NZ_CP012648_4	4.6\|1905177\|18\|NZ_CP012648\|CRT	1905177-1905194	18	NZ_CP012648.1	1904205-1904222	2	0.889
NZ_CP012648_4	4.7\|1905213\|18\|NZ_CP012648\|CRT	1905213-1905230	18	NZ_CP012648.1	1902441-1902458	2	0.889
NZ_CP012648_4	4.7\|1905213\|18\|NZ_CP012648\|CRT	1905213-1905230	18	NZ_CP012648.1	1904961-1904978	2	0.889
NZ_CP012648_4	4.8\|1905249\|18\|NZ_CP012648\|CRT	1905249-1905266	18	NZ_CP012648.1	1903701-1903718	2	0.889
NZ_CP012648_4	4.9\|1905285\|18\|NZ_CP012648\|CRT	1905285-1905302	18	NZ_CP012648.1	1904565-1904582	2	0.889

1. spacer 4.9|1905285|18|NZ_CP012648|CRT matches to position: 1905825-1905842, mismatch: 0, identity: 1.0

agcggatgtgcttgcact	CRISPR spacer
agcggatgtgcttgcact	Protospacer
******************

2. spacer 4.9|1905285|18|NZ_CP012648|CRT matches to position: 1905933-1905950, mismatch: 0, identity: 1.0

agcggatgtgcttgcact	CRISPR spacer
agcggatgtgcttgcact	Protospacer
******************

3. spacer 4.12|1905393|18|NZ_CP012648|CRT matches to position: 1901937-1901954, mismatch: 0, identity: 1.0

cgcggacgtacttgcaga	CRISPR spacer
cgcggacgtacttgcaga	Protospacer
******************

4. spacer 4.12|1905393|18|NZ_CP012648|CRT matches to position: 1902585-1902602, mismatch: 0, identity: 1.0

cgcggacgtacttgcaga	CRISPR spacer
cgcggacgtacttgcaga	Protospacer
******************

5. spacer 4.12|1905393|18|NZ_CP012648|CRT matches to position: 1903449-1903466, mismatch: 0, identity: 1.0

cgcggacgtacttgcaga	CRISPR spacer
cgcggacgtacttgcaga	Protospacer
******************

6. spacer 4.12|1905393|18|NZ_CP012648|CRT matches to position: 1903665-1903682, mismatch: 0, identity: 1.0

cgcggacgtacttgcaga	CRISPR spacer
cgcggacgtacttgcaga	Protospacer
******************

7. spacer 4.12|1905393|18|NZ_CP012648|CRT matches to position: 1904097-1904114, mismatch: 0, identity: 1.0

cgcggacgtacttgcaga	CRISPR spacer
cgcggacgtacttgcaga	Protospacer
******************

8. spacer 4.15|1905501|18|NZ_CP012648|CRT matches to position: 1904601-1904618, mismatch: 0, identity: 1.0

cgcggactcactggcaga	CRISPR spacer
cgcggactcactggcaga	Protospacer
******************

9. spacer 4.16|1905537|18|NZ_CP012648|CRT matches to position: 1904601-1904618, mismatch: 0, identity: 1.0

cgcggactcactggcaga	CRISPR spacer
cgcggactcactggcaga	Protospacer
******************

10. spacer 4.17|1905573|18|NZ_CP012648|CRT matches to position: 1905609-1905626, mismatch: 0, identity: 1.0

agccgaagtacttgcact	CRISPR spacer
agccgaagtacttgcact	Protospacer
******************

11. spacer 4.3|1905069|18|NZ_CP012648|CRT matches to position: 1903845-1903862, mismatch: 1, identity: 0.944

agctgattcgctcgaact	CRISPR spacer
agctgattcgctcgcact	Protospacer
************** ***

12. spacer 4.4|1905105|18|NZ_CP012648|CRT matches to position: 1904961-1904978, mismatch: 1, identity: 0.944

ggctgattcgctcgaact	CRISPR spacer
ggctgattcgctcgcact	Protospacer
************** ***

13. spacer 4.6|1905177|18|NZ_CP012648|CRT matches to position: 1904169-1904186, mismatch: 1, identity: 0.944

agctgattcgctcgctga	CRISPR spacer
agctgattcgcttgctga	Protospacer
************.*****

14. spacer 4.7|1905213|18|NZ_CP012648|CRT matches to position: 1901769-1901786, mismatch: 1, identity: 0.944

ggccgattcactcgcact	CRISPR spacer
ggccgattcgctcgcact	Protospacer
*********.********

15. spacer 4.7|1905213|18|NZ_CP012648|CRT matches to position: 1902729-1902746, mismatch: 1, identity: 0.944

ggccgattcactcgcact	CRISPR spacer
ggctgattcactcgcact	Protospacer
***.**************

16. spacer 4.7|1905213|18|NZ_CP012648|CRT matches to position: 1903521-1903538, mismatch: 1, identity: 0.944

ggccgattcactcgcact	CRISPR spacer
ggccgattcgctcgcact	Protospacer
*********.********

17. spacer 4.7|1905213|18|NZ_CP012648|CRT matches to position: 1903917-1903934, mismatch: 1, identity: 0.944

ggccgattcactcgcact	CRISPR spacer
ggccgattcgctcgcact	Protospacer
*********.********

18. spacer 4.7|1905213|18|NZ_CP012648|CRT matches to position: 1903989-1904006, mismatch: 1, identity: 0.944

ggccgattcactcgcact	CRISPR spacer
ggctgattcactcgcact	Protospacer
***.**************

19. spacer 4.7|1905213|18|NZ_CP012648|CRT matches to position: 1904457-1904474, mismatch: 1, identity: 0.944

ggccgattcactcgcact	CRISPR spacer
ggcggattcactcgcact	Protospacer
*** **************

20. spacer 4.10|1905321|18|NZ_CP012648|CRT matches to position: 1905609-1905626, mismatch: 1, identity: 0.944

agccgaagtacttgcgct	CRISPR spacer
agccgaagtacttgcact	Protospacer
***************.**

21. spacer 4.12|1905393|18|NZ_CP012648|CRT matches to position: 1901805-1901822, mismatch: 1, identity: 0.944

cgcggacgtacttgcaga	CRISPR spacer
cgcggacgtacttgctga	Protospacer
*************** **

22. spacer 4.12|1905393|18|NZ_CP012648|CRT matches to position: 1902369-1902386, mismatch: 1, identity: 0.944

cgcggacgtacttgcaga	CRISPR spacer
cgcggacgtacttgctga	Protospacer
*************** **

23. spacer 4.12|1905393|18|NZ_CP012648|CRT matches to position: 1904925-1904942, mismatch: 1, identity: 0.944

cgcggacgtacttgcaga	CRISPR spacer
cgcggacgtacttgctga	Protospacer
*************** **

24. spacer 4.1|1904997|18|NZ_CP012648|CRT matches to position: 1903701-1903718, mismatch: 2, identity: 0.889

tgcggactcacttgcaga	CRISPR spacer
tgcggactcgcttgccga	Protospacer
*********.***** **

25. spacer 4.3|1905069|18|NZ_CP012648|CRT matches to position: 1902081-1902098, mismatch: 2, identity: 0.889

agctgattcgctcgaact	CRISPR spacer
agccgattcgctcgcact	Protospacer
***.********** ***

26. spacer 4.3|1905069|18|NZ_CP012648|CRT matches to position: 1902333-1902350, mismatch: 2, identity: 0.889

agctgattcgctcgaact	CRISPR spacer
agccgattcgctcgcact	Protospacer
***.********** ***

27. spacer 4.3|1905069|18|NZ_CP012648|CRT matches to position: 1902765-1902782, mismatch: 2, identity: 0.889

agctgattcgctcgaact	CRISPR spacer
agctgattcgctggcact	Protospacer
************ * ***

28. spacer 4.3|1905069|18|NZ_CP012648|CRT matches to position: 1903197-1903214, mismatch: 2, identity: 0.889

agctgattcgctcgaact	CRISPR spacer
agctgattcgctggcact	Protospacer
************ * ***

29. spacer 4.3|1905069|18|NZ_CP012648|CRT matches to position: 1904853-1904870, mismatch: 2, identity: 0.889

agctgattcgctcgaact	CRISPR spacer
agctgattcgcttgcact	Protospacer
************.* ***

30. spacer 4.4|1905105|18|NZ_CP012648|CRT matches to position: 1901769-1901786, mismatch: 2, identity: 0.889

ggctgattcgctcgaact	CRISPR spacer
ggccgattcgctcgcact	Protospacer
***.********** ***

31. spacer 4.4|1905105|18|NZ_CP012648|CRT matches to position: 1902729-1902746, mismatch: 2, identity: 0.889

ggctgattcgctcgaact	CRISPR spacer
ggctgattcactcgcact	Protospacer
*********.**** ***

32. spacer 4.4|1905105|18|NZ_CP012648|CRT matches to position: 1903521-1903538, mismatch: 2, identity: 0.889

ggctgattcgctcgaact	CRISPR spacer
ggccgattcgctcgcact	Protospacer
***.********** ***

33. spacer 4.4|1905105|18|NZ_CP012648|CRT matches to position: 1903917-1903934, mismatch: 2, identity: 0.889

ggctgattcgctcgaact	CRISPR spacer
ggccgattcgctcgcact	Protospacer
***.********** ***

34. spacer 4.4|1905105|18|NZ_CP012648|CRT matches to position: 1903989-1904006, mismatch: 2, identity: 0.889

ggctgattcgctcgaact	CRISPR spacer
ggctgattcactcgcact	Protospacer
*********.**** ***

35. spacer 4.5|1905141|18|NZ_CP012648|CRT matches to position: 1902873-1902890, mismatch: 2, identity: 0.889

tgcggactcactcgcaga	CRISPR spacer
tgctgattcactcgcaga	Protospacer
*** **.***********

36. spacer 4.5|1905141|18|NZ_CP012648|CRT matches to position: 1903305-1903322, mismatch: 2, identity: 0.889

tgcggactcactcgcaga	CRISPR spacer
tgctgattcactcgcaga	Protospacer
*** **.***********

37. spacer 4.6|1905177|18|NZ_CP012648|CRT matches to position: 1901697-1901714, mismatch: 2, identity: 0.889

agctgattcgctcgctga	CRISPR spacer
agctgattcactcgcaga	Protospacer
*********.***** **

38. spacer 4.6|1905177|18|NZ_CP012648|CRT matches to position: 1904205-1904222, mismatch: 2, identity: 0.889

agctgattcgctcgctga	CRISPR spacer
agctgattcgcttgcgga	Protospacer
************.** **

39. spacer 4.7|1905213|18|NZ_CP012648|CRT matches to position: 1902441-1902458, mismatch: 2, identity: 0.889

ggccgattcactcgcact	CRISPR spacer
ggctgattcactggcact	Protospacer
***.******** *****

40. spacer 4.7|1905213|18|NZ_CP012648|CRT matches to position: 1904961-1904978, mismatch: 2, identity: 0.889

ggccgattcactcgcact	CRISPR spacer
ggctgattcgctcgcact	Protospacer
***.*****.********

41. spacer 4.8|1905249|18|NZ_CP012648|CRT matches to position: 1903701-1903718, mismatch: 2, identity: 0.889

tgcagactcgcttgcaga	CRISPR spacer
tgcggactcgcttgccga	Protospacer
***.*********** **

42. spacer 4.9|1905285|18|NZ_CP012648|CRT matches to position: 1904565-1904582, mismatch: 2, identity: 0.889

agcggatgtgcttgcact	CRISPR spacer
agcggattcgcttgcact	Protospacer
******* .*********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

735480 : 745302

Streptococcus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053794304.1\|735480_737685_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	4.2e-283	66.3
WP_172672760.1\|737766_737910_+	hypothetical protein	NA	NA	NA	NA
WP_053794305.1\|737924_738428_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_053794306.1\|738437_738956_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_053794307.1\|738952_739552_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	8.1e-56	59.1
WP_053794308.1\|739845_741306_+	LCP family protein	A0A1X9I5X1	Streptococcus_phage	1.1e-143	63.2
WP_053794309.1\|741309_742041_+	tyrosine protein phosphatase	NA	NA	NA	NA
WP_046164515.1\|742071_742767_+	capsular biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	1.0e-62	57.8
WP_053794310.1\|742776_743472_+	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	1.9e-80	67.9
WP_053794889.1\|743496_745302_+	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	1.0e-24	28.5

DBSCAN-SWA_2

1294999 : 1299754

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046165304.1\|1294999_1295863_-	YitT family protein	M1Q1P6	Streptococcus_phage	2.0e-95	61.0
WP_012130610.1\|1296116_1296755_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.3e-75	65.6
WP_046165305.1\|1296751_1297651_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.6e-82	55.1
WP_008809472.1\|1297665_1297989_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.5e-32	71.0
WP_046165306.1\|1297991_1298846_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.0e-100	66.2
WP_046165307.1\|1298893_1299391_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.2e-57	65.2
WP_046165308.1\|1299400_1299754_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.0e-34	58.1

DBSCAN-SWA_3

1720861 : 1744738

Streptococcus_phage(85.71%)

transposase,integrase

attL 1720610:1720623|attR 1743671:1743684

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1720610:1720623	attL	NA	NA	NA	NA
WP_000420682.1\|1720861_1721176_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|1721191_1721578_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|1721606_1722992_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|1722994_1723147_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|1723169_1724375_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|1724417_1724639_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|1724755_1725253_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|1725227_1725734_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|1725717_1728165_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000804748.1\|1728167_1730345_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000769868.1\|1730341_1731343_+	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_001224320.1\|1731339_1732275_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
WP_001791010.1\|1732519_1732636_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_053794614.1\|1732651_1734571_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	98.6
WP_000336323.1\|1734689_1734857_+	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_001814874.1\|1735470_1735554_+	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_001038790.1\|1735678_1736416_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_000576156.1\|1736770_1737325_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
WP_053794615.1\|1737328_1740247_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	9.1e-169	36.0
WP_000804885.1\|1741046_1741469_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|1741465_1741696_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000814511.1\|1742156_1742360_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|1742441_1743659_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_053794616.1\|1743937_1744738_+	SDR family oxidoreductase UcpA	A0A0G2Y8L6	Acanthamoeba_polyphaga_mimivirus	3.0e-05	30.9
1743671:1743684	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2020579 : 2081836

Streptococcus_phage(86.05%)

tRNA,integrase,protease,terminase,holin,tail,capsid

attL 2030733:2030748|attR 2088993:2089008

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046165784.1\|2020579_2022007_-\|protease	serine protease	NA	NA	NA	NA
WP_053794727.1\|2022230_2024240_-	cell wall protein	NA	NA	NA	NA
WP_046165786.1\|2025042_2025915_+	N-acetylmuramoyl-L-alanine amidase family protein	NA	NA	NA	NA
WP_046165787.1\|2025998_2026289_-	cupin domain-containing protein	NA	NA	NA	NA
WP_046165959.1\|2026349_2027066_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_080937024.1\|2027180_2027495_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_046165788.1\|2027487_2028456_-	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_046165789.1\|2028632_2029082_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_046165790.1\|2029243_2029567_-	TfoX/Sxy family protein	NA	NA	NA	NA
WP_053794728.1\|2029621_2030110_-\|tRNA	prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
WP_053794729.1\|2030122_2030707_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
2030733:2030748	attL	NA	NA	NA	NA
WP_053794730.1\|2030759_2032163_-	dipeptidase PepV	NA	NA	NA	NA
WP_046165792.1\|2032239_2032845_-	nitroreductase family protein	NA	NA	NA	NA
WP_046165793.1\|2032959_2034624_-	hypothetical protein	NA	NA	NA	NA
WP_046165794.1\|2034637_2035477_-	metallophosphoesterase family protein	NA	NA	NA	NA
WP_008808949.1\|2035733_2036279_-	hypothetical protein	NA	NA	NA	NA
WP_053794731.1\|2036449_2038279_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_172672770.1\|2038321_2039056_-	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_046165797.1\|2039201_2040128_-	hypothetical protein	NA	NA	NA	NA
WP_046165798.1\|2040181_2041015_-	AraC family transcriptional regulator	D0R0F8	Streptococcus_phage	8.6e-80	52.3
WP_002909597.1\|2041211_2041706_-	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_046165799.1\|2042079_2042871_-	nicotinamide riboside transporter PnuC	A0A2K9VCL6	Lactobacillus_phage	2.4e-15	27.0
WP_046165800.1\|2043607_2044243_-	hypothetical protein	NA	NA	NA	NA
WP_046165801.1\|2044287_2046111_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	7.5e-20	25.4
WP_053794732.1\|2046233_2047046_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_008808966.1\|2047275_2047803_+	hypothetical protein	NA	NA	NA	NA
WP_046165803.1\|2047862_2048168_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_053794733.1\|2048584_2048938_-	hypothetical protein	NA	NA	NA	NA
WP_053794734.1\|2049088_2049718_-	hypothetical protein	NA	NA	NA	NA
WP_053794735.1\|2049725_2050040_-	hypothetical protein	B3GW23	Streptococcus_phage	4.1e-43	81.4
WP_053794736.1\|2050055_2050343_-	hypothetical protein	B3GW22	Streptococcus_phage	6.2e-46	94.7
WP_053794737.1\|2050357_2050672_-	hypothetical protein	B3GW21	Streptococcus_phage	1.8e-51	94.2
WP_080998600.1\|2050878_2051619_-	SH3 domain-containing protein	J7KH48	Streptococcus_phage	2.4e-41	59.3
WP_053794739.1\|2051615_2051951_-\|holin	phage holin	A0A1S5SFY1	Streptococcus_phage	1.2e-32	70.6
WP_053794740.1\|2051954_2052356_-	hypothetical protein	Q9AF62	Streptococcus_phage	7.3e-53	82.6
WP_053794741.1\|2052384_2053020_-	hypothetical protein	Q9AF63	Streptococcus_phage	2.4e-26	36.5
WP_053794742.1\|2053019_2053241_-	hypothetical protein	NA	NA	NA	NA
WP_053794743.1\|2053255_2057134_-\|tail	phage tail protein	E8ZDP3	Streptococcus_phage	5.7e-126	37.4
WP_053794744.1\|2057130_2057835_-\|tail	phage tail family protein	M1Q167	Streptococcus_phage	2.1e-63	51.7
WP_053794745.1\|2057834_2061017_-	hypothetical protein	Q9F4J3	Streptococcus_phage	5.7e-132	61.8
WP_053794746.1\|2061016_2061391_-	DUF5361 domain-containing protein	Q9F4J4	Streptococcus_phage	5.8e-36	62.1
WP_053794747.1\|2061405_2061675_-	hypothetical protein	Q9F4J5	Streptococcus_phage	1.4e-20	52.9
WP_053794748.1\|2061678_2062266_-	hypothetical protein	Q9F4J6	Streptococcus_phage	1.3e-66	71.6
WP_053794749.1\|2062281_2062617_-	hypothetical protein	A0A1S5SG59	Streptococcus_phage	5.4e-41	73.0
WP_053794750.1\|2062617_2062854_-	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	9.0e-19	61.5
WP_053794751.1\|2062846_2063185_-	hypothetical protein	A0A1P8BMP0	Lactococcus_phage	2.6e-43	72.3
WP_053794752.1\|2063171_2063567_-	hypothetical protein	Q7Y4I2	Streptococcus_phage	1.0e-51	81.7
WP_053794753.1\|2063572_2063806_-	hypothetical protein	M1PKH2	Streptococcus_phage	6.6e-14	57.5
WP_053794754.1\|2063807_2064698_-\|capsid	phage major capsid protein	M1PF50	Streptococcus_phage	3.1e-144	85.8
WP_053794755.1\|2064701_2065160_-	DUF4355 domain-containing protein	Q7Y4I5	Streptococcus_phage	1.9e-44	71.4
WP_053794756.1\|2065242_2066655_-\|terminase	terminase	Q7Y4I6	Streptococcus_phage	1.9e-265	96.1
WP_053794757.1\|2066764_2067004_-	hypothetical protein	A0A1S5SD22	Streptococcus_phage	1.4e-38	88.6
WP_053794758.1\|2066993_2068385_-	hypothetical protein	A0A141E170	Streptococcus_phage	2.7e-195	70.6
WP_053794759.1\|2068374_2069643_-	hypothetical protein	Q7Y4J0	Streptococcus_phage	1.5e-208	89.3
WP_080998602.1\|2069883_2070222_-	HNH endonuclease	Q7Y4J1	Streptococcus_phage	5.6e-54	88.9
WP_053794760.1\|2070466_2071033_-\|integrase	site-specific integrase	Q7Y4J2	Streptococcus_phage	8.1e-82	78.2
WP_053794761.1\|2071135_2071603_-	hypothetical protein	B3GVZ7	Streptococcus_phage	1.3e-32	53.2
WP_053794762.1\|2071617_2071962_-	helix-turn-helix transcriptional regulator	C5J9A2	Streptococcus_phage	2.6e-35	63.9
WP_053794763.1\|2071977_2072754_-	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	8.6e-42	38.6
WP_155465134.1\|2072750_2072909_-	hypothetical protein	NA	NA	NA	NA
WP_080998603.1\|2072918_2073785_-	phage replisome organizer N-terminal domain-containing protein	Q7Y4K5	Streptococcus_phage	7.3e-58	78.4
WP_053794764.1\|2073789_2074044_-	hypothetical protein	NA	NA	NA	NA
WP_053794765.1\|2074053_2074314_-	hypothetical protein	NA	NA	NA	NA
WP_053794766.1\|2074717_2074993_-	DUF1372 family protein	A0A1P8VVQ5	Streptococcus_phage	3.3e-20	73.8
WP_053794767.1\|2075005_2075341_-	hypothetical protein	C5J997	Streptococcus_phage	1.4e-36	89.3
WP_053794768.1\|2075341_2075881_-	DUF1642 domain-containing protein	A0A2H4JBN7	uncultured_Caudovirales_phage	1.5e-29	51.1
WP_053794769.1\|2075873_2076140_-	DUF3310 domain-containing protein	B3GVZ1	Streptococcus_phage	3.3e-41	96.5
WP_053794770.1\|2076150_2076408_-	hypothetical protein	NA	NA	NA	NA
WP_053794771.1\|2076400_2076682_-	hypothetical protein	NA	NA	NA	NA
WP_053794772.1\|2076730_2076997_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_053794773.1\|2077076_2077505_-	ORF6C domain-containing protein	NA	NA	NA	NA
WP_053794774.1\|2077501_2078410_-	hypothetical protein	A0A286QMZ8	Streptococcus_phage	8.3e-44	66.9
WP_053794775.1\|2078431_2078623_-	DNA-binding protein	A0A1S5SA94	Streptococcus_phage	1.1e-27	96.8
WP_053794776.1\|2078636_2078822_-	helix-turn-helix transcriptional regulator	A0A1S5SDG0	Streptococcus_phage	9.9e-13	54.1
WP_053794778.1\|2079585_2079933_+	helix-turn-helix transcriptional regulator	A0A1S5SBE7	Streptococcus_phage	1.1e-44	78.2
WP_053794779.1\|2079944_2080331_+	ImmA/IrrE family metallo-endopeptidase	C5J979	Streptococcus_phage	2.2e-46	69.6
WP_053794780.1\|2080342_2080612_+	hypothetical protein	NA	NA	NA	NA
WP_053794781.1\|2080732_2081836_+\|integrase	site-specific integrase	Q938N9	Temperate_phage	1.3e-67	40.5
2088993:2089008	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2250123 : 2257586

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053794856.1\|2250123_2250618_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	1.8e-16	33.3
WP_172672778.1\|2250607_2251156_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_053794858.1\|2251228_2251717_-	YcxB family protein	NA	NA	NA	NA
WP_053794859.1\|2251899_2252577_+	helix-turn-helix transcriptional regulator	Q6DMX1	Streptococcus_phage	1.9e-53	46.5
WP_053794860.1\|2252580_2253996_+	Y-family DNA polymerase	M1Q231	Streptococcus_phage	1.2e-171	63.6
WP_053794861.1\|2253992_2254367_+	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	7.1e-10	32.1
WP_053794862.1\|2254344_2254638_+	hypothetical protein	NA	NA	NA	NA
WP_053794863.1\|2254711_2256295_-	hypothetical protein	V5US45	Oenococcus_phage	6.3e-23	31.0
WP_053794864.1\|2256365_2257586_-	DNA cytosine methyltransferase	V5URQ5	Oenococcus_phage	5.4e-131	58.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012648

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection