| NZ_CP012669.1|WP_061921817.1|268885_269563_-|twin-arginine-translocation-pathway-signal |
gnl|CDD|379310 |
pfam13645, YkuD_2, L,D-transpeptidase catalytic domain. This family is related to pfam03734.
|
1.23277e-47 |
| NZ_CP012669.1|WP_061921768.1|249567_250356_+|LytTR-family-transcriptional-regulator |
gnl|CDD|335768 |
pfam04397, LytTR, LytTr DNA-binding domain. This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.
|
1.02207e-20 |
| NZ_CP012669.1|WP_061921782.1|258181_258787_+|Holliday-junction-branch-migration-protein-RuvA |
gnl|CDD|234645 |
PRK00116, ruvA, Holliday junction branch migration protein RuvA.
|
4.99701e-76 |
| NZ_CP012669.1|WP_061921773.1|252873_254463_-|alkyl-hydroperoxide-reductase-subunit-F |
gnl|CDD|237942 |
PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.
|
0 |
| NZ_CP012669.1|WP_061927518.1|256848_257931_-|chorismate-synthase |
gnl|CDD|235438 |
PRK05382, PRK05382, chorismate synthase; Validated.
|
0 |
| NZ_CP012669.1|WP_061921814.1|267476_268859_+|L,D-transpeptidase-family-protein |
gnl|CDD|225536 |
COG2989, COG2989, Uncharacterized protein conserved in bacteria [Function unknown].
|
5.43177e-59 |
| NZ_CP012669.1|WP_061921776.1|254630_255197_-|peroxiredoxin |
gnl|CDD|211789 |
TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].
|
3.64981e-127 |
| NZ_CP012669.1|WP_083440037.1|262972_263398_-|rhodanese-like-domain-containing-protein |
gnl|CDD|238089 |
cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.
|
8.47685e-25 |
| NZ_CP012669.1|WP_061921823.1|270971_272117_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase |
gnl|CDD|234737 |
PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.
|
0 |
| NZ_CP012669.1|WP_061921811.1|266418_267300_-|DMT-family-transporter |
gnl|CDD|223769 |
COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].
|
6.73455e-09 |
| NZ_CP012669.1|WP_061921765.1|248860_249406_-|DUF2306-domain-containing-protein |
gnl|CDD|227683 |
COG5395, COG5395, Predicted membrane protein [Function unknown].
|
1.61426e-29 |
| NZ_CP012669.1|WP_061921770.1|250443_252660_-|catalase/peroxidase-HPI |
gnl|CDD|237891 |
PRK15061, PRK15061, catalase/peroxidase.
|
0 |
| NZ_CP012669.1|WP_061921780.1|255414_256845_-|serine-hydrolase |
gnl|CDD|365903 |
pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
|
8.64764e-69 |
| NZ_CP012669.1|WP_083440038.1|269608_270526_-|histone-deacetylase |
gnl|CDD|212519 |
cd09993, HDAC_classIV, Histone deacetylase class IV also known as histone deacetylase 11. Class IV histone deacetylases (HDAC11; EC 3.5.1.98) are predicted Zn-dependent enzymes. This class includes animal HDAC11, plant HDA2 and related bacterial deacetylases. Enzymes in this subfamily participate in regulation of a number of different processes through protein modification (deacetylation). They catalyze hydrolysis of N(6)-acetyl-lysine of histones (or other proteins) to yield a deacetylated proteins. Histone deacetylases often act as members of large multi-protein complexes such as mSin3A or SMRT/N-CoR. Human HDAC11 does not associate with them but can interact with HDAC6 in vivo. It has been suggested that HDAC11 and HDAC6 may use non-histone proteins as their substrates and play a role other than to directly modulate chromatin structure. In normal tissues, expression of HDAC11 is limited to kidney, heart, brain, skeletal muscle and testis, suggesting that its function might be tissue-specific. In mammals, HDAC11 proteins are known to be involved in progression of various tumors. HDAC11 plays an essential role in regulating OX40 ligand (OX40L) expression in Hodgkin lymphoma (HL); selective inhibition of HDAC11 expression significantly up-regulates OX40L and induces apoptosis in HL cell lines. Thus, inhibition of HDAC11 could be a therapeutic drug option for antitumor immune response in HL patients.
|
2.67556e-130 |
| NZ_CP012669.1|WP_061921807.1|263397_266073_-|aconitate-hydratase-AcnA |
gnl|CDD|236445 |
PRK09277, PRK09277, aconitate hydratase AcnA.
|
0 |
| NZ_CP012669.1|WP_061921801.1|262192_262903_-|2OG-Fe(II)-oxygenase |
gnl|CDD|214780 |
smart00702, P4Hc, Prolyl 4-hydroxylase alpha subunit homologues. Mammalian enzymes catalyse hydroxylation of collagen, for example. Prokaryotic enzymes might catalyse hydroxylation of antibiotic peptides. These are 2-oxoglutarate-dependent dioxygenases, requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as a cofactor.
|
4.90449e-22 |
| NZ_CP012669.1|WP_061921788.1|259277_260321_+|Holliday-junction-branch-migration-DNA-helicase-RuvB |
gnl|CDD|234619 |
PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.
|
0 |
