CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012390	Lawsonella clevelandensis strain X1698 chromosome, complete genome	6 crisprs	WYL,cas3,DEDDh,cas9,cas1,cas2,cas6e,cas5,cas7,cse2gr11,cas8e,cas4,DinG,csa3	5	16	2	0

1. NZ_CP012390

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012390_1

• CRISPR_ID: NZ_CP012390_1
• CRISPR_location: 535942-536034
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP012390_1

Consensus_repeat	Method
GTCGCAGGTGCAATCGGGGCCGCA	CRISPRCasFinder

spacers of NZ_CP012390_1

>1.1|535966|45|NZ_CP012390|CRISPRCasFinder
CTCGTTCTTACCACAGTGTCCTTCTGCGCAGCAGGTGCAGGTATC

CRISPR arrays and Neighbor proteins around NZ_CP012390_1

CRISPR arrays

The CRISPR arrays of NZ_CP012390_1

>merge|NZ_CP012390|1|535942-536034|CRISPRCasFinder
GTCGCAGGTGCAATCGGGGCCGCACTCGTTCTTACCACAGTGTCCTTCTGCGCAGCAGGTGCAGGTATCGGTGCAGGTGCAATCGGGGCCGCA

>NZ_CP012390|1|1|535942-536034|CRISPRCasFinder
GTCGCAGGTGCAATCGGGGCCGCA	CTCGTTCTTACCACAGTGTCCTTCTGCGCAGCAGGTGCAGGTATC
GGTGCAGGTGCAATCGGGGCCGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012390.1|WP_053962657.1|530544_531240_-|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|236115
NZ_CP012390.1|WP_053961640.1|521893_522613_+|MspA-family-porin	unknown	unknown	gnl|CDD|370360
NZ_CP012390.1|WP_053961654.1|544815_545229_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP012390.1|WP_053961644.1|528696_530319_+|threonine/serine-exporter-family-protein	unknown	unknown	gnl|CDD|377697
NZ_CP012390.1|WP_053961645.1|531445_532297_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381357
NZ_CP012390.1|WP_148417486.1|525154_525736_-|suppressor-of-fused-domain-protein	unknown	unknown	gnl|CDD|377450
NZ_CP012390.1|WP_053961651.1|541591_542668_+|hypothetical-protein	unknown	unknown	gnl|CDD|369272
NZ_CP012390.1|WP_053961653.1|543928_544726_-|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NZ_CP012390.1|WP_053961652.1|542664_543501_-|RNA-methyltransferase	unknown	unknown	gnl|CDD|223640
NZ_CP012390.1|WP_082345579.1|525911_528506_-|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319795
NZ_CP012390.1|WP_053961641.1|522722_524027_+|MspA-family-porin	unknown	unknown	gnl|CDD|370360
NZ_CP012390.1|WP_053961650.1|540345_541599_+|DUF3071-domain-containing-protein	unknown	unknown	gnl|CDD|378619
NZ_CP012390.1|WP_053961647.1|534007_535744_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|312032
NZ_CP012390.1|WP_082345328.1|545704_546724_+|transglycosylase-family-protein	unknown	unknown	gnl|CDD|369056
NZ_CP012390.1|WP_053961649.1|539059_540181_+|phosphoserine-transaminase	unknown	unknown	gnl|CDD|130433
NZ_CP012390.1|WP_053961648.1|537713_538745_-|hypothetical-protein	unknown	unknown	gnl|CDD|185699
NZ_CP012390.1|WP_053961642.1|524023_525001_+|MspA-family-porin	unknown	unknown	unknown
NZ_CP012390.1|WP_082345327.1|543591_543921_+|DUF2530-domain-containing-protein	unknown	unknown	gnl|CDD|378488
NZ_CP012390.1|WP_053961646.1|532586_533924_+|hypothetical-protein	unknown	unknown	gnl|CDD|200456
NZ_CP012390.1|WP_053962658.1|536267_537545_-|citrate-synthase	unknown	unknown	gnl|CDD|99867

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012390.1|WP_053962657.1|530544_531240_-|enoyl-CoA-hydratase	gnl|CDD|236115	PRK07854, PRK07854, enoyl-CoA hydratase; Provisional.	1.58379e-94
NZ_CP012390.1|WP_053961640.1|521893_522613_+|MspA-family-porin	gnl|CDD|370360	pfam09203, MspA, MspA. MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel.	3.2322e-26
NZ_CP012390.1|WP_053961654.1|544815_545229_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	4.83485e-23
NZ_CP012390.1|WP_053961644.1|528696_530319_+|threonine/serine-exporter-family-protein	gnl|CDD|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	3.22699e-48
NZ_CP012390.1|WP_053961645.1|531445_532297_-|aldo/keto-reductase	gnl|CDD|381357	cd19131, AKR_AKR5C2, Escherichia coli 2,5-diketo-D-gluconic acid reductase A (DkgA/YqhE) and similar proteins. Escherichia coli DkgA/YqhE is a founding member of aldo-keto reductase family 5 member C2 (AKR5C2). DkgA/YqhE (EC 1.1.1.274), also called 2,5-DKG reductase A, or 2,5-DKGR A, or 25DKGR-A, or AKR5C, catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives.	1.41336e-133
NZ_CP012390.1|WP_148417486.1|525154_525736_-|suppressor-of-fused-domain-protein	gnl|CDD|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	4.29469e-10
NZ_CP012390.1|WP_053961651.1|541591_542668_+|hypothetical-protein	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	0.000146083
NZ_CP012390.1|WP_053961653.1|543928_544726_-|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	6.40337e-97
NZ_CP012390.1|WP_053961652.1|542664_543501_-|RNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	1.40897e-49
NZ_CP012390.1|WP_082345579.1|525911_528506_-|HAD-IC-family-P-type-ATPase	gnl|CDD|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NZ_CP012390.1|WP_053961641.1|522722_524027_+|MspA-family-porin	gnl|CDD|370360	pfam09203, MspA, MspA. MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel.	1.61847e-22
NZ_CP012390.1|WP_053961650.1|540345_541599_+|DUF3071-domain-containing-protein	gnl|CDD|378619	pfam11268, DUF3071, Protein of unknown function (DUF3071). Some members in this family of proteins are annotated as DNA-binding proteins however this cannot be confirmed. Currently no function is known.	1.07549e-43
NZ_CP012390.1|WP_053961647.1|534007_535744_+|alpha/beta-fold-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	4.48977e-09
NZ_CP012390.1|WP_082345328.1|545704_546724_+|transglycosylase-family-protein	gnl|CDD|369056	pfam06737, Transglycosylas, Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues.	2.84486e-42
NZ_CP012390.1|WP_053961648.1|537713_538745_-|hypothetical-protein	gnl|CDD|185699	cd09022, Aldose_epim_Ec_YihR, Aldose 1-epimerase, similar to Escherichia coli YihR. Proteins similar to Escherichia coli YihR are uncharacterized members of aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism, catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen.	1.71407e-90
NZ_CP012390.1|WP_053961649.1|539059_540181_+|phosphoserine-transaminase	gnl|CDD|130433	TIGR01366, Putative_phosphoserine_aminotransferase_PSAT., phosphoserine aminotransferase, putative. This model represents a putative variant form of the serine biosynthesis enzyme phosphoserine aminotransferase, as found in Mycobacterium tuberculosis and related high-GC Gram-positive bacteria. [Amino acid biosynthesis, Serine family].	0
NZ_CP012390.1|WP_082345327.1|543591_543921_+|DUF2530-domain-containing-protein	gnl|CDD|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	3.97625e-21
NZ_CP012390.1|WP_053961646.1|532586_533924_+|hypothetical-protein	gnl|CDD|200456	cd11317, AmyAc_bac_euk_AmyA, Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase). AmyA (EC 3.2.1.1) catalyzes the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides. This group includes AmyA proteins from bacteria, fungi, mammals, insects, mollusks, and nematodes. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	4.08617e-102
NZ_CP012390.1|WP_053962658.1|536267_537545_-|citrate-synthase	gnl|CDD|99867	cd06114, EcCS_like, Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS reaction is thought to proceed through three partial reactions and involves both closed and open conformational forms of the enzyme: a) the carbanion or equivalent is generated from AcCoA by base abstraction of a proton, b) the nucleophilic attack of this carbanion on OAA to generate citryl-CoA, and c) the hydrolysis of citryl-CoA to produce citrate and CoA. There are two types of CSs: type I CS and type II CSs. Type I CSs are found in eukarya, gram-positive bacteria, archaea, and in some gram-negative bacteria and are homodimers with both subunits participating in the active site. Type II CSs are unique to gram-negative bacteria and are homohexamers of identical subunits (approximated as a trimer of dimers). Some type II CSs including EcCS are strongly and specifically inhibited by NADH through an allosteric mechanism. Included in this group is an NADH-insensitive type II Acetobacter acetii CS which has retained many of the residues used by EcCS for NADH binding.	0

Protein sequences

>NZ_CP012390.1|WP_053961647.1|534007_535744_+|alpha/beta-fold-hydrolase
MAFPRANHKVLSLVTGTALTAGLLASPYAAVAQAAEQPGDTLHWGPCPKDVLSNPAYHMQCTTFKVPLDYRKPHGKKITITMSRIKATGHSRGIILNNPGGPGGSGLNLWNWMVSAGAGPLHKHFDLISVQPRGLQHATPLKPCVDPTVPEIDSPEKDEERDLPKNLAGAKEKVTKTVSELQRLVGDVDPKDSASKAKEKAQAEYKRCVKDYGALFDQVTTENTARDFDMARQYLGEQKINFYGASYGTWLGAVYATIFPEHTGRFVLDSAVDPSEIWTNNFGNQGDMQRRRMYEMFDFIAAHDDLYHLGDTPLKVYTKWYRIIEKETHGPGTPRLSAPPAQIGDVPPEFSHNIQLYLEGYNLARPIADRIERAIHAWQVPSTEQEHNLWELTGSAFTGRSAWPKVASYMQRPRPKPLTKAEKEEQIISANVFTAVTCNENAVAPSPVNLPATAAAYFTGADFFTLKNLIVTSGVMCPGIVPTTKPVQVTGAYLKIRPVVLQSVYDTQTPYPGGVKMADAMNAYFVKTEGGDHGVYVRHNPAAWKLVNDYYLKDPVVTRTSLPYATVDNLVVKPDEKK
>NZ_CP012390.1|WP_053961646.1|532586_533924_+|hypothetical-protein
MFQWPWNAIAEECRSSLGTMGIRRVLISPPHENLNIPTWTSSYAPISYRLDSKLGTRDELRRMVETCHAHGVDIIADAVMNHMAPAIPPFRGIAGSTFHRYSYPGIYSSADFHHCHLTPDGVLHTYFDRGQVQQCDALGLPDLDTGSPHVQKVLHAYLRDLLSVGVDGFRIDAAKHISAADVAGILSVVPADKFVVQEVIIGLHEPIHPQEYFQNGRVFDFAFAGVVKDALQYGDLFGLFSTGAERGLLPLSQAVPIVTNHDFERDVNLLTYRDGWVYHFATLLMLATQHGSPFLYSGYAFDSRDQPAPSTPAGLVDTPHCTPHLLRPRVGQFLCVQRDAAYRTMVEWRYRAMNGTLQPRQNHTSDIPVLAPARIVWFQPGVVALMRNGLLFVANWSGHPVKIPLAPGQTDSTSLISLHAGRVELDHTLLTVPQGDIVVSMRAAH
>NZ_CP012390.1|WP_053961645.1|531445_532297_-|aldo/keto-reductase
MSPHHSAPVPQVILNDQTSIPQLGFGVYKVPEDDAYRVVSEALEVGYRLIDTAALYGNEEGVGRAIRESGIPRDEIFVTTKLWNTDHGKKETVDAFHASLDRLGLAYVDLYLIHWPQPAVDKYVETWEEMIALRDTDELRSIGVSNFTAPTLKRIISETGVVPVLNQIELHPGFSQPDMRKFNSYFSVRTQAWSPLARGEGLDANAITALAEKYGKTPAQIVLRWHMQLGTLVIPKTTHRERMEENFDVLDFWMGEEELASITNMDRADGRMSKDPDEFNGDL
>NZ_CP012390.1|WP_053962657.1|530544_531240_-|enoyl-CoA-hydratase
MTLRNPERRNALNAELCRGIQLAVERVEHEGCRSLVITGTGEVFCAGADLTGGVFSSGFANQNVAMLRTIERSKLIIIAYVNGAAIGAGAQLAMACDLRVADDEAFFALPVAKMGFALDNWTVRRLESLVGGGFARTILYTGDPFHVKESAAHGLVNKVGNIDDALAWAQEIATYAPLTLHHLKLVFNNDLAQQQPTPMQAAAAKTAWISEDLKEARRAFAEGRRPRFRGI
>NZ_CP012390.1|WP_053961644.1|528696_530319_+|threonine/serine-exporter-family-protein
MTSDDSAQNKTPEDLPETSAVIAETVHNAVEDAVAETVTDPVKERQEIDDPSTLAERTTTVIRLGSLLLAAGTGGYRVKRAMQRAAFALGIDRFDASVTLTNITATAYIKDDYRTLVSEAPAIGVNASRIEALESISRDISHGISNADLNARIDHVVKWVKPRYGLWVNGLASGFACAAFAVLNKFPPEALLFVLLGATLGQMTRRVLGHRGWNQMGVAALAGVVASVIYLLCVSITAEIVPGFIYNSANAGYAPVSAGFVASVLFLIPGFPMFTSLLDLAKLDFNSGIQRFTYMLTLLAAATSSVWIVTLATGLQPLPQIGNPYQVRFGAEWWPLYVWVASFIGIAGFAVLFNCSRRMALLSSATGATANLLKFILIDHSIVGLHLPTQTGAFIAALFIGLVAAIIAPTMRIPRITMSVPSAVIMIPGASMYRFIYFLNIGDLGLAARNLLDAGLVVIAIGAGLAVARMVTDPEWLYDRRHPRFHRRHLIGRTQRAILGVQAARRAAKKAIREAARHDAHRIEREKTGPTQHAVSKFQD
>NZ_CP012390.1|WP_082345579.1|525911_528506_-|HAD-IC-family-P-type-ATPase
MLDEADYTPAEGLTEDQVSEIRAAGNGNDHRVRAGRSVGEIIRANVFTRINAMLGVLLIIVLSTGSIINAAFGLLIIANSGIGIIQEIRAKRMLDKLSIVGQAKPMVRRQKESGSQDFEIPATELVQGDLIVLSAGEQILVDGEVISAQALDVNESLLTGENDPVHKEPGDVVLSGSFVVAGSGVYQATKVGTEAYAAKLATEASQFTLTNSQLMTGINKILRVITWLLMPTGIATIYTQLFQTGKPWNEAVLSMAAALVPMVPEGLVLMASIAFFVGVIRLGQKQCLVQELPAIEGLARVDVVCTDKTGTLTNNSMELKEVTPLGEAAEDETLAQAAQQALAAMAIYDDHPNDSMKAIAEWATSGHDDAYAGEQDWEQTAVVPFSSDKKWSAMGFGKHGEWMLGAPDVLAAPDSSAAATADEVGSTGLRVLLLARSDTPVDELAHTPAEEFVEAGTVTPVALVVLQQSVRPDAADTLEYFHGEGVDVKVVSGDNATSVGAVASELTMVGADAPLDARKLPKLSEDAFAQRSRRQESTVSTAAAEFADDVENHTVFGRVTPEQKRFMVGALQHNGHTVAMTGDGVNDVLALKRADIGVAMGSGSSAARSVAQIVLLDNRFATLPSVVGEGRRVIGNIERVANLFLTKTVYSVLLALLVVFAQVPFPFQPIHVTITGWFTIGIPAFLLSLAPNTARAKDHFVQRVLRLAVPSGVIISAVSFVTYMVLRHVYGEGGASISDTLQTQISTATLATLIVTATWVLCVVARPLRWWKILLVVLSAAMYPVIFLWPFTAKVFFLDATNGVLMEWGLLAGLCGAVLVEILWWVTGAVKGEQHFVWARTRERFEVEQQDAKMAEAARKRSAS
>NZ_CP012390.1|WP_148417486.1|525154_525736_-|suppressor-of-fused-domain-protein
MEPAVIAHMEERLGRIRGSVPGSRHAHWTVVFSEVPARLASRMPVAFKAQRLSAVWSVGLSFVPLVSPQTRHKLRLELFTLCDPQDRFEAERVIGAVAEAIDTTNTPILRGQVIGPLPPDAGVHAVYASLPRMFDGEFPTCQTEYGPVAVVWLFPIGPSEEKFIMAEGWQEFEKKLFRRFDIDPADWGRLSCC
>NZ_CP012390.1|WP_053961642.1|524023_525001_+|MspA-family-porin
MTLSSHPRHTMRHTARSVTALATTIGVVLTTVPVAAAAPIAPTTGALTARSASTPDLEPLLPTFLQRHISFATEQRTYVNPEKGKVQTVIRRSGLTNSSALFDLDRNGDVTLEVRTRVDPSYRVAYFYAGVQYGCFGGVGDPKVETSIDTNTTISVNGKWKTHATTYPITQFLQQSARTAVKGAIAGAECGASEGPGCAEMAKFLATEVPREVFATLELARIITNTGTSEMGVSAKPKIVPTFSASVYPGQTSVVPFYFLRYSPGWNTVRVTNMNLQGSGCIGPAYIRPFVVTLGRTKSGNYVNYQLIGQSYPFYPNKLFRMSER
>NZ_CP012390.1|WP_053961641.1|522722_524027_+|MspA-family-porin
MLQRSSISLLLAASLLSASVATTPFAFAAPAAHDPGTTLRQKVDTALTESRTSYSVPDVERTIITEDGEKVTLAKNNEHIYRTAPLNRNLLTHEARVSLQGLAKVAGSSQRSIHTLTVGYLMGCQIDASEPAKLEVSFPMQIQLPSPRIGTEGDFSAPDFEQNRKSLGVTLLRPQLWFGYVAGVTLSDEISYNVNVKPGRIAKVPLASFSFRGNRTSWADLRDVHMFIDGCPGNVSLRSYVEYLDGAISPRHFPTPSSETKNSAKLLNSKKMKKPKRARFAQQTDSLKQVKQSKIRLPRLNPDQSVSLPKKKSKRGFKDKYPVALTPREKAQQEAYRDLTRKMAEVGNPSGASLDRPYGKQNPDTVEGLKFTIHGAVRWMSTILPQTDLATDARNREKVVREMWEPVQEYAKRFVNTLASIFIPLGIPSPKGLL
>NZ_CP012390.1|WP_053961640.1|521893_522613_+|MspA-family-porin
MKLRRLTASTLATMTFFGASFSTANAIPIHKTGSNYTTTTEDGLTLNVTRSHEQFELQLPDNLSIFSHQTFLDTKGVATIKGATGKALDAHIMIGYQLGCMIDVSDGATFEFGAPKLTTGVELKQALNGMPSIKGEGSADGGGAEISGVGATTTLTPKAGLEVPLGPDVKFTLKPGQIITFLVTEKDVKGSKGALRYVGEPINVDGCLGFASVRSFITLWTKAPIEDSKITTWGKVTRF
>NZ_CP012390.1|WP_053962658.1|536267_537545_-|citrate-synthase
MAKLILPDGDIDLPIVHATEGYDGVQLGALLNKTGMITLDNGYVNTGSCESRITYIDGDKGILRYRGYPIEELAEKATFMEVAYLLIHGHLPDFAELEDFRMSIKYNTELDWDFRKLYEAIPRWGHPMPSMSAAVNLLSCYNQDCLDPHDPEQVEKATRVLMGQVPMLTADIYRHLHGMAPMYPRHEYTLVENFLRMMFGSPSQEYELDPELVHTMEVLLILHADHEQNCSTSTVRMVGSSQANLFVSIAAGINALYGPLHGGANQAVLEMLEKIRDDGGDAHDYMERVKSKEDGVRLMGFGHRVYKNYDPRAAIVKKHAHRVIDMLGGDELLDIALALEEKALADDYFVERRLYPNVDFYTGLIYRAMGFPTQMFTPLFAFGRLPGWIAQWREQNSDPRNKIGRPRQVYKGETERAFVPLEDRQ
>NZ_CP012390.1|WP_053961648.1|537713_538745_-|hypothetical-protein
MDESFEDKIALEIEAQLVSGRTIALESGPYRALIDRQGAAVQGLWWTPSEGATEVPLAEPYGAESPFTCGQTLIPWPNRIADARFLFQETPVALEMSEPALHNAIHGLATAALWDVSEKASDGSFVTLSFRSGPALGNGWPWEFSVVVRYEVSAAGLTVAVSVKNESRQAMPWGYGAHPYITAGGAALNACTLQASVDEWWVTDDRNLPTGEHLPIGEGVPLLRQPTSMEDVWFDTPFTVAQDTPVDVGWRELARLTGPVAEDQNVSVVMDADSGFTWLQIFTTGEKTVMFPGKDTEEGRALAVEPMTCPPNAMVTGQDVIVLEPFAEWSGQWRVHGEVSDHL
>NZ_CP012390.1|WP_053961649.1|539059_540181_+|phosphoserine-transaminase
MTDAMITIPADLLPADGRFGCGPSKVRAAQLDSLLNPGASIMGTSHRQPAVKNVVKRIQEGLLDLFQAPEGYEVVLGIGGATAFWDAATFGLIRERSLNLTFGEFSSKFATASKKAPWLQDPVIVAAEPGSAPTPVTDDSCDLIGWAHNETSTGVMLGVERPEGSDGALIAIDATSGSGGLPVNIADADCYYFSPQKCYASDGGLWLAVMSPAAIDRIEEISTSGRFIPGFLDLKTALDNSRKNQTYNTPAVATLLMLANQVEWMNENGGLDFTVGRTTDSSSRLYEWAEKSEFATPFVTDPALRSLVVGTIDFNDEVDAAAVAKALRANGVLDTEPYRKLGRNQLRIGMFPAIDPEDVSQLTKCIDYVVDHL
>NZ_CP012390.1|WP_053961650.1|540345_541599_+|DUF3071-domain-containing-protein
MRELHVAGYNADENSIILRDPTTEEEFSVIADEQLRAAARGDVPGLRQVRIEKSNTMRPSEIQELIRAGASTDELADRAGMQRSRLDNLARPILMERANMVRRAQESHPLLADGPSDITLAMAAHTGLSTRGIDYHDGSWDSWKTADGHWIIELRWEEGHADNTAHWRFQQDRSYAITSPIDETASELTDPSFVPSRPTSVTSISNLGAARLRNSRTSQETRHQLAVAAQRDAAGLPDGSRPGSVRRRTPGYVKSVTVSMDDLTNPTTPGPVRSLESVEASPPATAASPAPAETTRSTAKSRASKSTKNTTSTPPTEQLSLDNIRQFAAYKSGTAADIPDSSADKSTPSASSQPEEDEGTTPPIAKFIPPVKPLSASPSAHSADDDHSRRAARKKQKHPTMPSWEDVLLGVRGQQND
>NZ_CP012390.1|WP_053961651.1|541591_542668_+|hypothetical-protein
MTNSAEHAVVTLWFVSAPDAHALLATNPQPDAEYGLQLVAGLFPEKPVTPLGTFPLTRSAPAGHTEVYVGTYPGATVLQTAAIPLNRMLDLVPEWVQPDAADDIYAFAQGPSGTFAGFAHWRQGKLERAFSATACEILEDKGLPLGVEGPYWAGQYPVPKEIDLGSDFAIPLPFLPGDMLLTLYTAWLGFEPRAHHLNILVNGFALDGRPEARPMDRNVPDDDALLRFPEMGTGVSADELAAAELEEATGEVANAAKDDASEGRKRGGRRANALAGKEDKAHKDGLWTRFKRWWNGDPVEEDALATSDEDFSPYADYAPDTATGDGYSAEDAVGDGYSDAGNYQAYTAAYGEDYTDKC
>NZ_CP012390.1|WP_053961652.1|542664_543501_-|RNA-methyltransferase
MVHMIPIADPLDSRIDGFRNLNHAEKRRDHAGSDGVVIGEGSLVTDRMLASWCPPTQFLGTEAGLARLTAMPDYGELAASTPFYLATEDVISECVGFHFNRHIFALAPRPAPRAVEDVLAHSPRTLAVLEGLNDHANIGSIFRNAAALGVGGVLTGAGCADPLYRRSVRVSMGHVLRIPFAPCTGGPNDWQEPTFAQLRAAGYRILALTPAHDAQVLADVAEGGKVAFIVGAEGPGLRRKTMRLADARVQIPMQIGVDSLNVATSAAVAFYERARTHH
>NZ_CP012390.1|WP_082345327.1|543591_543921_+|DUF2530-domain-containing-protein
MTRRYRENMKKRSIPALPARLIDPRPVIAAGTAAWLVSLVTLLVAGVHATAMWVAVCGVGVGVGIYAIFAWQRSAVRRGAATAQTSLPDVQREGDKAVDRVIVEIPHQQ
>NZ_CP012390.1|WP_053961653.1|543928_544726_-|DUF3027-domain-containing-protein
MSDDIAKTPPSANPTPLGSSAAEALARQAVADLHSGGAGELLGAQTEDNGSTTYRFSSDLPGYRGWEWQVVLSGEDSHPTLDELALMPGNDALLAPAWVPWEDRLQPGDLSDGDILPVAEDDPRLVPGYVDSGDDELDDAAMPIGYGRERVLSPEGRDEAATRWAKGEYGPHSTRAKKAPARCETCGFYLPLAGALKASFGVCANRLSADGHVVHVRYGCGAHSSIQEDHSAARPADMYFDDAEFELVAKPVGATIPADKTSGNV
>NZ_CP012390.1|WP_053961654.1|544815_545229_-|cold-shock-protein
MPHGKVKWYDPEKGFGFITQEEGEDVYVRASVLPEGVTELKPGQRVDMDIVAGRRGPQALRLEVLAPAPSVSANQRKQRRQSAHRHTPDELHGMIEDMITLMESAVQPELRKGRYPDRKTAQHISEIVRAVARELDH
>NZ_CP012390.1|WP_082345328.1|545704_546724_+|transglycosylase-family-protein
MGAHSAQGRQFGIADVKKAVSSIALSGAAALAVGVISSPLASAAPNSDWDRLAQCESGGNWHINTGNGYYGGLQFSQGTWAAHGGTNYAPSADLATRDQQIAVAEHVLATQGWGAWPACSSSLGLSSGPTPRNTVTPGELAKKKRLAEQKRREAQRRERENNFIQYKTTETAGVVVETAANLGLPVDEKKADKAIDKANKGFTNKVVKPARKASKESDSAALQKVDSTYTKVNRSAAKVVEGDGGVEEKLYAPSSKLNAVTDGATPVVGANTAKTASTGSAKVSATGTKSTKTLPLQTEKKVEKKTNSQNAKKGEKNKKDKKDKKDSLLTILPLSVLYD

Crispr_ID: NZ_CP012390_2

• CRISPR_ID: NZ_CP012390_2
• CRISPR_location: 842688-842948
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP012390_2

Consensus_repeat	Method
TGGTGGGGGTGTTGGGGTTGGTGCCGG	CRISPRCasFinder

spacers of NZ_CP012390_2

>2.1|842715|60|NZ_CP012390|CRISPRCasFinder
GTTGGGGGAGGATGCGTTCGGTGTTGTGTGCTGAGCGGCGGGGGCGGCGGGGTGTGGTCT
>2.2|842802|42|NZ_CP012390|CRISPRCasFinder
TTCCGGGGGTTCCGGGGATGCCGGATGTGCCGGGGCGGCCTG
>2.3|842871|51|NZ_CP012390|CRISPRCasFinder
TGCCGGATTTAGCTGGGGAGCCTGAACCGGCAGGGGCTTTCGTGCTGGAAC

CRISPR arrays and Neighbor proteins around NZ_CP012390_2

CRISPR arrays

The CRISPR arrays of NZ_CP012390_2

>merge|NZ_CP012390|2|842688-842948|CRISPRCasFinder
GGATGGGGCCGTGGGGGAGGTTGCCGGGTTGGGGGAGGATGCGTTCGGTGTTGTGTGCTGAGCGGCGGGGGCGGCGGGGTGTGGTCTTGCTGGTGGTGTTGTGGCTTGTTCCTGTTCCGGGGGTTCCGGGGATGCCGGATGTGCCGGGGCGGCCTGTGCTGGTGGTGGGGGTGTTGGGGTTGGTGCCGGATTTAGCTGGGGAGCCTGAACCGGCAGGGGCTTTCGTGCTGGAACTGGTGGGGGTGTTGGGGTTGGTGCCGG

>NZ_CP012390|2|2|842688-842948|CRISPRCasFinder
GGATGGGGCCGTGGGGGAGGTTGCCGG	GTTGGGGGAGGATGCGTTCGGTGTTGTGTGCTGAGCGGCGGGGGCGGCGGGGTGTGGTCT
TGCTGGTGGTGTTGTGGCTTGTTCCTG	TTCCGGGGGTTCCGGGGATGCCGGATGTGCCGGGGCGGCCTG
TGCTGGTGGTGGGGGTGTTGGGGTTGG	TGCCGGATTTAGCTGGGGAGCCTGAACCGGCAGGGGCTTTCGTGCTGGAAC
TGGTGGGGGTGTTGGGGTTGGTGCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012390.1|WP_053961894.1|854214_855786_-|polysaccharide-pyruvyl-transferase-family-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961892.1|851367_852297_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP012390.1|WP_082345380.1|838280_839174_-|MspA-family-porin	unknown	unknown	gnl|CDD|370360
NZ_CP012390.1|WP_148562326.1|836045_836462_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_148562327.1|844438_845167_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_082345382.1|850331_851366_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224057
NZ_CP012390.1|WP_148562325.1|835680_836049_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961890.1|847037_848204_-|hypothetical-protein	unknown	unknown	gnl|CDD|238861
NZ_CP012390.1|WP_053961882.1|840905_841466_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_172621882.1|855958_856327_-|GtrA-family-protein	unknown	unknown	gnl|CDD|225155
NZ_CP012390.1|WP_053961893.1|852348_854112_-|hypothetical-protein	unknown	unknown	gnl|CDD|99795
NZ_CP012390.1|WP_053961881.1|840488_840905_+|thermonuclease-family-protein	unknown	unknown	gnl|CDD|366169
NZ_CP012390.1|WP_053961880.1|839479_839857_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961889.1|845660_846758_-|hypothetical-protein	unknown	unknown	gnl|CDD|238861
NZ_CP012390.1|WP_053961883.1|841770_842523_+|DNA-alkylation-repair-protein	unknown	unknown	gnl|CDD|132880
NZ_CP012390.1|WP_082345381.1|839863_840070_-|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl|CDD|377942
NZ_CP012390.1|WP_053961891.1|848308_849313_+|NAD(P)H-quinone-oxidoreductase	unknown	unknown	gnl|CDD|176180
NZ_CP012390.1|WP_053961877.1|836467_838006_-|amidase-domain-containing-protein	unknown	unknown	gnl|CDD|378910
NZ_CP012390.1|WP_053961878.1|837998_838250_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053962688.1|849430_850312_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224596

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012390.1|WP_082345380.1|838280_839174_-|MspA-family-porin	gnl|CDD|370360	pfam09203, MspA, MspA. MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel.	7.55795e-24
NZ_CP012390.1|WP_053961883.1|841770_842523_+|DNA-alkylation-repair-protein	gnl|CDD|132880	cd06561, AlkD_like, A new structural DNA glycosylase. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity.	2.8245e-22
NZ_CP012390.1|WP_082345382.1|850331_851366_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224057	COG1134, TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.21044e-121
NZ_CP012390.1|WP_053961890.1|847037_848204_-|hypothetical-protein	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	2.89456e-20
NZ_CP012390.1|WP_172621882.1|855958_856327_-|GtrA-family-protein	gnl|CDD|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	1.65843e-17
NZ_CP012390.1|WP_053961893.1|852348_854112_-|hypothetical-protein	gnl|CDD|99795	cd06198, FNR_like_3, NAD(P) binding domain of ferredoxin reductase-like proteins catalyze electron transfer between an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) domain, which varies in orientation with respect to the NAD(P) binding domain. The N-terminal domain may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Ferredoxin is reduced in the final stage of photosystem I. The flavoprotein Ferredoxin-NADP+ reductase transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) which then transfers a hydride ion to convert NADP+ to NADPH.	5.29844e-26
NZ_CP012390.1|WP_053961892.1|851367_852297_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	1.60759e-43
NZ_CP012390.1|WP_053962688.1|849430_850312_+|ABC-transporter-permease	gnl|CDD|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	5.70659e-67
NZ_CP012390.1|WP_053961889.1|845660_846758_-|hypothetical-protein	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	3.88158e-16
NZ_CP012390.1|WP_082345381.1|839863_840070_-|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl|CDD|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	3.49052e-08
NZ_CP012390.1|WP_053961881.1|840488_840905_+|thermonuclease-family-protein	gnl|CDD|366169	pfam00565, SNase, Staphylococcal nuclease homolog. Present in all three domains of cellular life. Four copies in the transcriptional coactivator p100: these, however, appear to lack the active site residues of Staphylococcal nuclease. Positions 14 (Asp-21), 34 (Arg-35), 39 (Asp-40), 42 (Glu-43) and 110 (Arg-87) [SNase numbering in parentheses] are thought to be involved in substrate-binding and catalysis.	3.07868e-27
NZ_CP012390.1|WP_053961891.1|848308_849313_+|NAD(P)H-quinone-oxidoreductase	gnl|CDD|176180	cd05276, p53_inducible_oxidoreductase, PIG3 p53-inducible quinone oxidoreductase. PIG3 p53-inducible quinone oxidoreductase, a medium chain dehydrogenase/reductase family member, acts in the apoptotic pathway. PIG3 reduces ortho-quinones, but its apoptotic activity has been attributed to oxidative stress generation, since overexpression of PIG3 accumulates reactive oxygen species. PIG3 resembles the MDR family member quinone reductases, which catalyze the reduction of quinone to hydroxyquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	5.6469e-119
NZ_CP012390.1|WP_053961877.1|836467_838006_-|amidase-domain-containing-protein	gnl|CDD|378910	pfam12671, Amidase_6, Putative amidase domain.	1.88089e-21

Protein sequences

>NZ_CP012390.1|WP_053961883.1|841770_842523_+|DNA-alkylation-repair-protein
MCEHINTQASSANELRTQLEELGEPPLRSFNARLVPTESDEALLGIRIPTLRQIAKDLWRHNRPLADAFLSDLPHRYLEENLLHMLLLNQLRDADEYATALEPFLPHITNWMVSDAAGPKLPTEELQRLEPYLRTWLADSHTYTSRVGGVLLMSNYLRDLFRPEHLQWVARIPSQDYYSHMLQGWYLATALVTQPDAIWPVLRDPEAAGVPLSVEARLKAIQKSIESRRISAGDKTELRALRAAIRGRHA
>NZ_CP012390.1|WP_053961882.1|840905_841466_-|hypothetical-protein
MKRAATVALTGFLMLSLGAGIAQAEPYSDPATTPGKIVVHPKPQPLIQPPIEATVYAQPYGLVPDFHAASNFSPLGTQKNIRVRGPLLQPNRYSLFFKTRAACQADLDPYGHDYGALNPIVPQHWVWMAKNDATQQISTQCYQIYNGMWVYEYNNFFEMPVVQNPQNLPGHYPKNVPAEQKKYLRK
>NZ_CP012390.1|WP_053961881.1|840488_840905_+|thermonuclease-family-protein
MAARTLRVIDGDTAVFNIAGRKTTVRFIGVNTPETVKPNSPVECFGEQASAFTSSNLTDKSVYLELDPSQSKYDRYGRMLAYVWLGKTLYNLELIEEGYAYEATYAGPYRYQAEFKAAEKDARDHNRGLWNPRVCPQR
>NZ_CP012390.1|WP_082345381.1|839863_840070_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MVKEQKYRTVTSFLQENGWKLLRQGKGSHEIWWHPGSGDRVIVPHHKNISAGVLQGIGKHIPLPKEWR
>NZ_CP012390.1|WP_053961880.1|839479_839857_-|hypothetical-protein
MSTHYDVVAEPEGRWWIVRVPSLEITGQARNLAEVDDVAAEIIGLWLDCPTSEITTTVTLKIPDSIQKILDKASTQEKEAEQLARDARTTRSAALHQLVDGGLTITDTAKLVKLSRQRVSQLITA
>NZ_CP012390.1|WP_082345380.1|838280_839174_-|MspA-family-porin
MLRTFSPRFQSRFLCRGMASIAACSLCLSCGLSTAYAWEPGIDGSRADVIRSGKTIDGWTVTAKKQGERFRIVAPLAGDASSHEGFISLQGIGEITGKGTSKVLQGTVDVGYMVGCGVDISDGFTIGQSYSASLTPSVGLSTDKGVSSQTTGHGSVTPSGSLTGNGSLTPTVTLGFPISNVGGSATVGASATGGASATVGASDTLGGHANIGKHADLTTTLAHTSSFSAHVKPGYITTVWLLNAKLRSMRGGVSIIGANLAVTGCGTTVKIRSVVRFLVETEQGTAMVIAYGRPFRI
>NZ_CP012390.1|WP_053961878.1|837998_838250_-|hypothetical-protein
MKPRITNYLLGLVGFTALLVCCALLPLISTWATHYAPVLVYTAFFLIMMLVGAFLNKGVTQLSHDWTDWRHTKSTIPADTTDD
>NZ_CP012390.1|WP_053961877.1|836467_838006_-|amidase-domain-containing-protein
MTNLHRTLPTLVATLGLVLLPQGALHAHAEETPEERCQRETQAYNDAWKRQWSQNHPDAIATGQTPPPPPVPYRCVGTPSITPTSVPTPPAGGTNGASGSVGGGTPIPGHIDPITGLPSNTPPLNQPVTPGSSGYHAGNPPHNTPGQLDYNPTNPWIDGRRTGTPSTPPLNHPTPTNNPHHKQGIDRPNLGDWHPTPPETHPLNHHEKSSGIKNNKHSEATHFWQRLVDNLAPHRHMPPVQENYGSAPVPSVDDTSPVRSATSTHEKHPTSETTTDPLTLLLMTAGLLSGLHRRKHFVYTARSKTQPPLSPNRKKAVAYAEKWARGRNPDYPTRPTTAGADCTNFASQVLHAGGFKVEAPGPGKNDDSIQYWAPYKTVRIPSPSYGPAVETTDPSHPTRSWNNADALYHRLVDTNRGKVVGRVHGQDNGKNNLSPSQHGLQPGDLIFYENSTTHKMTHVAVYMGTKNGVDIVNQHSSAEDKHDYHDDWQTDTRNSEDIAVFVHVYYPGEPRR
>NZ_CP012390.1|WP_148562326.1|836045_836462_-|hypothetical-protein
MSSYAHRFRRLAAITLSLTLLTGIATVIPQSRALLVNRPYCNTLLYSYYPLEEEPYRRAFGLDGMWETLSDTSYLVTEHYDPRLAALQEASLLTYTVNTQTPLGIYFKDVYVMWGGFCRMTPPVVWHGDKHDPLHYSS
>NZ_CP012390.1|WP_148562325.1|835680_836049_-|hypothetical-protein
MTPPTRRATVILCLCLGLIFGITIPLSVENTRLTDRDFCQALPTRLPLDTTPSTPADAVSTMASLRSTYHLSNKAQLLTSFYMIFAINHHNIYNEYPHHTHYLTRAEKTALHDIYQHCGLPQ
>NZ_CP012390.1|WP_148562327.1|844438_845167_-|hypothetical-protein
MLRVALTVERFSPMMSSFSLTSPGKKLTAVAFVCTVLGGLAGCDNQSVLNDNTSASWSSSSQRNPDHIYANHTEGVEPDQSWDSVKTGEDVDRNLAIYRKWGLKQTSDWLAICNQVNVSALRKVGFDPQKDLLNRDGGVGKYSCYWSHNKGQIQFFFSQEKSLDEANHRDGFELRGVVKRDGRSYYMGHIKFVGEGTSLQGFECSLNYEHDGVAYAAAITGKDPKSHDEACNELMSIVTKVE
>NZ_CP012390.1|WP_053961889.1|845660_846758_-|hypothetical-protein
MQRKDLSRTQRVGIVAGTLAATVILAVSQLATGGLFTSHEEAIIASTENPQVATHKPSPTTHNNKERTPATSMAKKQPKKVAKTKIATPSSEIELPIPNPYPDGYPMVVFGDSTMSLAPTKKQAENPLSKCKHYEGAWPQRVSAKLGLPMADLSCAGARSGLYWKLNAKKYVGPTTRLVLLSYGSNDLHVQNQLISDNAFPGTGPYLPHAEQSAVEQDLVDVLQDIRALAPKAMIVTVGYLPLVEGVGCKNLPNMTPLEMARVENLRRGADESLSNATTRAADYSTAVMRDRGLEVASSGVFNVPFRDVTGHTLCAADPERFILNHEEVGARYHYTVPGLQYVTQAVVERYQSEVSLWEMQSRKL
>NZ_CP012390.1|WP_053961890.1|847037_848204_-|hypothetical-protein
MHNKLFRFTRRTVVAGALVLTAALGLGTIGTLTGVFSEDDGIATAQAALPNVVVPPESVTLTPKHTPDGSGSTSTGAGRSHGGTSRDSSPSPQDGSSVHLWDARQGMNFATGTNAAKKKPNRYRFGYPMVAFGDSTMALAPTERRTNPFGSCSHYTGTWPLQVSESLHLPLADLSCSGAKTGAYWQKQLDKYLGPRTQLVVVSYGSNDLRVVFQLISDNALPGTGPRFEGKTRQEVEGSLVKILRDVRKRAPNAMILTVGYLPLVQEAQCKNLPNMTRLETARVRHLRENADIALTNSTNRVATLSKQKWVNQGLQVVSPGIYNVPFRKVSGHDLCAKTSQRFILNKEKKGVRYHYTTKGLSYIADRVLRKYWSEQRVWQRQVRNFAH
>NZ_CP012390.1|WP_053961891.1|848308_849313_+|NAD(P)H-quinone-oxidoreductase
MYAHALPVCRGPRSLTWRHVPDPVPGPGEVLLQVAAVAVNRMDLAQTQGRYQPPAGVAPYPGIECSGRIVALGPDQPEGSPWQVGDECCALLNGGGYAELAVAPTLQLLPIPQGIALVDAAALPEAACVAWSTLVMEGRLAPGNTVLIEGGSGGMGSFAIQLAKALGAGVVAMAGTDQGVNLCWDLGADVALNYRDEDPVMSLRTLGGANVIFDLMGASHLAQHIECIAPGGRIVTVSLQGKLDNPVDMGVLMPQLMGKRGAIITTSMRSRPATGPGSKAEVIRHVTQHVWPLIATGLIGPVIQRRVPIRSAHDVLTDVQNRTTLGKSVLRVGR
>NZ_CP012390.1|WP_053962688.1|849430_850312_+|ABC-transporter-permease
MIPDHDHTGLGILAKTFEGEPPKSDSFTFKRAFGDLKDGWKSDQLWLQLGWQDIKQRYRRSTLGPLWITIATGVMAVALGLLYSLLFKEELSYFLPHVTLGLILWGFIAGCIQEGAQVFIANEGLIKQLPAPLSVHVYRLVWRQTLFLAHNMIIYIIMLAVFRPHLGWDALLFFPALLLFLLNGVWVAMFFGIISTRFRDVAPLVDSLVQLCFYMTPIVWTTHTLYANETMSQRARLAEINPLYHYLEIIRSPLMGIDVPAYHWYIVLGFTVVGWGLMLLVMKKARGRVSYWV
>NZ_CP012390.1|WP_082345382.1|850331_851366_+|ABC-transporter-ATP-binding-protein
MSHKENRAEAAAARAAERAARRAAHVSLSDRLHRPAPRTTDVSIDTYDACVDFPIFDARTRSLKQTFLGAAGGAIGRNNSNVVVVEALKNINLHLREGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGSAEVHGRVAPVFDLGIGMDPEISGYENIIIRGLFLGQTRQQMKEKMEEIAEFTELGEYLDMPLRTYSSGMRIRLALGVVTSIDPEILLLDEGLGAVDAAFMRKARHRLKDMVQRSGLLVFASHSNEFLAQLCDKAIWIDHGEAVLAGSVEEVVRAYEGNEAGDHVANIIAQMEREDRERGIDSRRLIVPHGIEQPGDDDSAAAGTDAGAAGEPGEGA
>NZ_CP012390.1|WP_053961892.1|851367_852297_+|glycosyltransferase-family-2-protein
MQVVGVVVTYNRTDVLGRSLDILAHQSRPLDHLIVVDNGNDPAVATLLENAGATANNGAGMAVTYLPSQHNLGGAGGFALGMLHALALGADWVWCADDDGHPDGPDVLRTLLDCVKRYHLDQVSPVVCTIDAPDTLAFPLRRGLVWRRTRDELFDDDDPQHQNMLLPGIASLMNGALFSAHCLDTIGVPDLRLFMRGDEVELHRRLERSGLKFGTCLATAYLHPNGADEFKPILGGRMHAQYPDSPAKRYYTYRNRGFLMAMPGKRSLLLQEYARFTWFFLVQQRDLAGFREWRRLRKLGRAEKLYRMP
>NZ_CP012390.1|WP_053961893.1|852348_854112_-|hypothetical-protein
MTSPRPTDANPIDASSTTELRRMAAPRRPEAHTSARQKIGYFVSATIKVLKANSGMLLSCVAALLLALLAYGDQLGEVELQAVYDFPAVVLQIVGLWLMVTGIGALDALPRVNKSFNGAEGMLRWNKIATVLGLAVEWLAYVIRRAALGSTHNTVDKHVSDTVLLVVLVLVTVLALLRYVGPNMRHAPRRGPGAWIARIPFDVIYPVFNAATVALWAVLAWQMWETSVLNQSMPDNNGTGAAGAGLAGTNSVPSVADVAGAVGLPCLLSAYCLVIIAAALVVLRVMIIQQFRTDRRYPGTVVKLMYPNPDTVIVTVELESRLQRGRPVGYWYTAGQYSYLGVPGQKGGPHPFTMTSIPNVVGRTGPTQHVGVGSRMRTQGMAWDRQVEYCIKAGGKGSRWLVDNVYEGMPVTVSTPRGGAHPAHGGVRQLWVAGGIGITPFVAWLRDLNLAVGEEFPGHVTLVWSYRPSEKPAYVNLVRECAQEWGWLTLVEVDTESGERLTPQQAHRIAFPLEGDESQPLLAGMPTAGAVALSGTEAVAGEAAPLYGEDITIHMCGPTDLCADYHTYFLEQGVSPDRMHVDAFHMR
>NZ_CP012390.1|WP_053961894.1|854214_855786_-|polysaccharide-pyruvyl-transferase-family-protein
MSVSSVLRHHPRRTWQAERPRIFYLVSPAGVPNWGDELIVATWLRYLARTHPDATVVVDCHSPGKAAVLLRGLHPNLVVTNTLWDLVERAGREVFPQGDTAVTTDEVNIDQLAKLCELTSSWVLDGGAQADLASNLDLVGNADVLHVVGGGYLNDMWPHHAAIIAAVAAVAERERPEGEPRPLFVATGAGLMPQRQGTILPYVLQADAVTVRDAASAAVLQRAVDSVVKLEAEGTRRSYQPLPRAEFSQVGDDTWVAVALGIVEEAEQRLEEAQTAAARRPVWKRWSEKLQYAGKLGVSGHPGTSAIPGQTGALGELAQPGDPAPGAVITSDLPLLEWGFQHLSCADTHGRFPYHPVPHGRSTVLCVQSDLVGDKEALWDWVRETLTEWQVTGPELLVVECIPYGDYVIWQQVVQEYFPGAEFVPFARLWREGLPVGEQVRWLSTRFHPHLLAAAAGCEGVAVDAHGLGYYSVKHESVQAAGSLWPVVHPVGLPVRPPHHSCDVSRRETSVRQALELAEAIYR
>NZ_CP012390.1|WP_172621882.1|855958_856327_-|GtrA-family-protein
MRFFITGCLSAVVDFGLLLLLSQLGMDPTMAKAISFICGTTTAYMINRRWTFQAAHSNKRLLAVCLLYAVTFGLNVGIFHVVYEAALPLGHLWAKTIGFVIGQAVATIVNFVVQRTVIFRVR

Crispr_ID: NZ_CP012390_3

• CRISPR_ID: NZ_CP012390_3
• CRISPR_location: 1007630-1009392
• CRISPR_type: orTypeII
• Repeat_type: NA
• Spacer_info: 27 spacers
• Cas_protein_info: cas2,cas1,cas9

Consensus repeat of NZ_CP012390_3

Consensus_repeat	Method
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGT	PILER-CR
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CRISPRCasFinder
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CRT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	PILER-CR

spacers of NZ_CP012390_3

>3.1|1007669|25|NZ_CP012390|PILER-CR
GACGGGTGAACACCTCCCCGAGGTC
>3.2|1007733|28|NZ_CP012390|PILER-CR
TGGGGATGAGTATAAGCAAGTAGCATCG
>3.3|1007666|28|NZ_CP012390|CRISPRCasFinder,CRT
GGTGACGGGTGAACACCTCCCCGAGGTC
>3.4|1007730|28|NZ_CP012390|CRISPRCasFinder,CRT
TGGGGATGAGTATAAGCAAGTAGCATCG
>3.5|1007794|28|NZ_CP012390|CRISPRCasFinder,CRT
GGTCAAGTTTGGAACTGCAGTCCGGCTC
>3.6|1007858|28|NZ_CP012390|CRISPRCasFinder,CRT
GTGACCTCCCGGAAGTGGCGGATCATCA
>3.7|1007922|28|NZ_CP012390|CRISPRCasFinder,CRT
CGCCCGTGATTGTTCCGCTCGACCCCAC
>3.8|1007986|28|NZ_CP012390|CRISPRCasFinder,CRT
TGCCGAACGTTCAGGTCTGAGTGATCTT
>3.9|1008050|28|NZ_CP012390|CRISPRCasFinder,CRT
GTGGGATCGTGAGGGGCGGAAAGTTCCT
>3.10|1008114|28|NZ_CP012390|CRISPRCasFinder,CRT
TGATGTGGATGAGTGTCTTTTCGCGTGG
>3.11|1008178|28|NZ_CP012390|CRISPRCasFinder,CRT
CGTATTGGTGCAGAGGTGCCGTACCGGG
>3.12|1008242|28|NZ_CP012390|CRISPRCasFinder,CRT
TACGTCGGATATTGTCTTTGAAGTAGGT
>3.13|1008306|28|NZ_CP012390|CRISPRCasFinder,CRT
GGCTGATCCGCTGGGCATTGACGACTTC
>3.14|1008370|28|NZ_CP012390|CRISPRCasFinder,CRT
GTGCTCGCAGTTGCTGCTGTGGGCACCT
>3.15|1008434|28|NZ_CP012390|CRISPRCasFinder,CRT
CGTATCCTGTTGAGTCTCTAGCCGCACG
>3.16|1008498|28|NZ_CP012390|CRISPRCasFinder,CRT
GCGATCGCACTGGTCAGTTGAAGGCGAG
>3.17|1008562|28|NZ_CP012390|CRISPRCasFinder,CRT
AATGAAGCTCGTATGTGCTCAAACCGGC
>3.18|1008626|28|NZ_CP012390|CRISPRCasFinder,CRT
TCATTGAGTAGTCGAAGGAGTAGCCACT
>3.19|1008690|28|NZ_CP012390|CRISPRCasFinder,CRT
AACGTCTGTTGACGTCTCTTCTGCCGAT
>3.20|1008754|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
TGCGGTTTGAGGATCGTAGGTGTTGAAA
>3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
ACCATCGCCGGCATGATCAACGGAGCAG
>3.22|1008882|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
TGCCACACGGGTTTAATGTCCGCGTCCA
>3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
CGCCGCACTCATGACCGTACTGGTCAGC
>3.24|1009010|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
TGGCGATGAGTATAAGCAAGTAGCATCG
>3.25|1009074|27|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
TTTTGGCTCGGTTGCAGGAGGAGTGGG
>3.26|1009137|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
CTCCCTTGGGCTATCCGAAGGGCGCGAG
>3.27|1009201|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
GGCCTTACGGGCAGCCTTGATAAACTCC
>3.28|1009265|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
TCAACCATCACGCTTACTATCCCGGATG
>3.29|1009329|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR
TAAATGATGAAAGAGTACACGGTGTGGA

CRISPR arrays and Neighbor proteins around NZ_CP012390_3

CRISPR arrays

The CRISPR arrays of NZ_CP012390_3

>merge|NZ_CP012390|3|1007630-1009392|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGTGACGGGTGAACACCTCCCCGAGGTCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGGGGATGAGTATAAGCAAGTAGCATCGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGTCAAGTTTGGAACTGCAGTCCGGCTCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGACCTCCCGGAAGTGGCGGATCATCAGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGCCCGTGATTGTTCCGCTCGACCCCACGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGCCGAACGTTCAGGTCTGAGTGATCTTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGGGATCGTGAGGGGCGGAAAGTTCCTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGATGTGGATGAGTGTCTTTTCGCGTGGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGTATTGGTGCAGAGGTGCCGTACCGGGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTACGTCGGATATTGTCTTTGAAGTAGGTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGCTGATCCGCTGGGCATTGACGACTTCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGCTCGCAGTTGCTGCTGTGGGCACCTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGTATCCTGTTGAGTCTCTAGCCGCACGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGCGATCGCACTGGTCAGTTGAAGGCGAGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACAATGAAGCTCGTATGTGCTCAAACCGGCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTCATTGAGTAGTCGAAGGAGTAGCCACTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACAACGTCTGTTGACGTCTCTTCTGCCGATGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGCGGTTTGAGGATCGTAGGTGTTGAAAGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACACCATCGCCGGCATGATCAACGGAGCAGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGCCACACGGGTTTAATGTCCGCGTCCAGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGCCGCACTCATGACCGTACTGGTCAGCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGGCGATGAGTATAAGCAAGTAGCATCGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTTTTGGCTCGGTTGCAGGAGGAGTGGGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCTCCCTTGGGCTATCCGAAGGGCGCGAGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGCCTTACGGGCAGCCTTGATAAACTCCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTCAACCATCACGCTTACTATCCCGGATGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTAAATGATGAAAGAGTACACGGTGTGGAGAGGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC

>NZ_CP012390|3|1|1007630-1007796|PILER-CR
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGT	GACGGGTGAACACCTCCCCGAGGTC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGG	GGATGAGTATAAGCAAGTAGCATCGGAA
GTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGTCAAGTTTGGAACTGCAGTCCGGCTCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGACCTCCCGGAAGTGGCGGATCATCAGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGCCCGTGATTGTTCCGCTCGACCCCACGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGCCGAACGTTCAGGTCTGAGTGATCTTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGGGATCGTGAGGGGCGGAAAGTTCCTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGATGTGGATGAGTGTCTTTTCGCGTGGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGTATTGGTGCAGAGGTGCCGTACCGGGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTACGTCGGATATTGTCTTTGAAGTAGGTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGCTGATCCGCTGGGCATTGACGACTTCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGCTCGCAGTTGCTGCTGTGGGCACCTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGTATCCTGTTGAGTCTCTAGCCGCACGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGCGATCGCACTGGTCAGTTGAAGGCGAGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACAATGAAGCTCGTATGTGCTCAAACCGGCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTCATTGAGTAGTCGAAGGAGTAGCCACTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACAACGTCTGTTGACGTCTCTTCTGCCGATGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCGGTTTGAGGATCGTAGGTGTTGAAA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	ACCATCGCCGGCATGATCAACGGAGCAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCCACACGGGTTTAATGTCCGCGTCCA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGCCGCACTCATGACCGTACTGGTCAGC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGGCGATGAGTATAAGCAAGTAGCATCG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TTTTGGCTCGGTTGCAGGAGGAGTGGG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CTCCCTTGGGCTATCCGAAGGGCGCGAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGCCTTACGGGCAGCCTTGATAAACTCC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TCAACCATCACGCTTACTATCCCGGATG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TAAATGATGAAAGAGTACACGGTGTGGA


>NZ_CP012390|3|3|1007630-1009392|CRISPRCasFinder
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGTGACGGGTGAACACCTCCCCGAGGTC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGGGGATGAGTATAAGCAAGTAGCATCG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGTCAAGTTTGGAACTGCAGTCCGGCTC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GTGACCTCCCGGAAGTGGCGGATCATCA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGCCCGTGATTGTTCCGCTCGACCCCAC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCCGAACGTTCAGGTCTGAGTGATCTT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GTGGGATCGTGAGGGGCGGAAAGTTCCT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGATGTGGATGAGTGTCTTTTCGCGTGG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGTATTGGTGCAGAGGTGCCGTACCGGG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TACGTCGGATATTGTCTTTGAAGTAGGT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGCTGATCCGCTGGGCATTGACGACTTC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GTGCTCGCAGTTGCTGCTGTGGGCACCT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGTATCCTGTTGAGTCTCTAGCCGCACG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GCGATCGCACTGGTCAGTTGAAGGCGAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	AATGAAGCTCGTATGTGCTCAAACCGGC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TCATTGAGTAGTCGAAGGAGTAGCCACT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	AACGTCTGTTGACGTCTCTTCTGCCGAT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCGGTTTGAGGATCGTAGGTGTTGAAA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	ACCATCGCCGGCATGATCAACGGAGCAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCCACACGGGTTTAATGTCCGCGTCCA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGCCGCACTCATGACCGTACTGGTCAGC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGGCGATGAGTATAAGCAAGTAGCATCG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TTTTGGCTCGGTTGCAGGAGGAGTGGG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CTCCCTTGGGCTATCCGAAGGGCGCGAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGCCTTACGGGCAGCCTTGATAAACTCC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TCAACCATCACGCTTACTATCCCGGATG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TAAATGATGAAAGAGTACACGGTGTGGA
GAGGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC

>NZ_CP012390|3|1|1007630-1009392|CRT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGTGACGGGTGAACACCTCCCCGAGGTC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGGGGATGAGTATAAGCAAGTAGCATCG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGTCAAGTTTGGAACTGCAGTCCGGCTC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GTGACCTCCCGGAAGTGGCGGATCATCA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGCCCGTGATTGTTCCGCTCGACCCCAC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCCGAACGTTCAGGTCTGAGTGATCTT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GTGGGATCGTGAGGGGCGGAAAGTTCCT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGATGTGGATGAGTGTCTTTTCGCGTGG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGTATTGGTGCAGAGGTGCCGTACCGGG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TACGTCGGATATTGTCTTTGAAGTAGGT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGCTGATCCGCTGGGCATTGACGACTTC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GTGCTCGCAGTTGCTGCTGTGGGCACCT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGTATCCTGTTGAGTCTCTAGCCGCACG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GCGATCGCACTGGTCAGTTGAAGGCGAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	AATGAAGCTCGTATGTGCTCAAACCGGC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TCATTGAGTAGTCGAAGGAGTAGCCACT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	AACGTCTGTTGACGTCTCTTCTGCCGAT
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCGGTTTGAGGATCGTAGGTGTTGAAA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	ACCATCGCCGGCATGATCAACGGAGCAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCCACACGGGTTTAATGTCCGCGTCCA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGCCGCACTCATGACCGTACTGGTCAGC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGGCGATGAGTATAAGCAAGTAGCATCG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TTTTGGCTCGGTTGCAGGAGGAGTGGG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CTCCCTTGGGCTATCCGAAGGGCGCGAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGCCTTACGGGCAGCCTTGATAAACTCC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TCAACCATCACGCTTACTATCCCGGATG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TAAATGATGAAAGAGTACACGGTGTGGA
GAGGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC

>NZ_CP012390|3|2|1008718-1009392|PILER-CR
	GACGGGTGAACACCTCCCCGAGGTC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGG	GGATGAGTATAAGCAAGTAGCATCGGAA
GTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGTCAAGTTTGGAACTGCAGTCCGGCTCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGACCTCCCGGAAGTGGCGGATCATCAGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGCCCGTGATTGTTCCGCTCGACCCCACGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGCCGAACGTTCAGGTCTGAGTGATCTTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGGGATCGTGAGGGGCGGAAAGTTCCTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTGATGTGGATGAGTGTCTTTTCGCGTGGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGTATTGGTGCAGAGGTGCCGTACCGGGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTACGTCGGATATTGTCTTTGAAGTAGGTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGGCTGATCCGCTGGGCATTGACGACTTCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGTGCTCGCAGTTGCTGCTGTGGGCACCTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACCGTATCCTGTTGAGTCTCTAGCCGCACGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACGCGATCGCACTGGTCAGTTGAAGGCGAGGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACAATGAAGCTCGTATGTGCTCAAACCGGCGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACTCATTGAGTAGTCGAAGGAGTAGCCACTGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAACAACGTCTGTTGACGTCTCTTCTGCCGATGAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCGGTTTGAGGATCGTAGGTGTTGAAA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	ACCATCGCCGGCATGATCAACGGAGCAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGCCACACGGGTTTAATGTCCGCGTCCA
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CGCCGCACTCATGACCGTACTGGTCAGC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TGGCGATGAGTATAAGCAAGTAGCATCG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TTTTGGCTCGGTTGCAGGAGGAGTGGG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	CTCCCTTGGGCTATCCGAAGGGCGCGAG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	GGCCTTACGGGCAGCCTTGATAAACTCC
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TCAACCATCACGCTTACTATCCCGGATG
GAAGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC	TAAATGATGAAAGAGTACACGGTGTGGA
GAGGTCTATCTGCAGGTTCTAGAGAAGAGAAACAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012390.1|WP_053961982.1|993431_995141_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP012390.1|WP_053961995.1|1013396_1013888_+|hypothetical-protein	unknown	unknown	gnl|CDD|234612
NZ_CP012390.1|WP_053961984.1|997129_997852_-|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|380324
NZ_CP012390.1|WP_082345405.1|995393_996053_+|ribonuclease-HI	unknown	unknown	gnl|CDD|260010
NZ_CP012390.1|WP_053961985.1|997896_999303_-|formate/nitrite-transporter-family-protein	unknown	unknown	gnl|CDD|376497
NZ_CP012390.1|WP_053961991.1|1009696_1010323_-|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|225462
NZ_CP012390.1|WP_053961986.1|999505_1000750_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961987.1|1001159_1002572_-|MFS-transporter	unknown	unknown	gnl|CDD|340897
NZ_CP012390.1|WP_053961999.1|1019524_1020187_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP012390.1|WP_053961996.1|1014242_1015988_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP012390.1|WP_053961990.1|1007259_1007580_+|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043
NZ_CP012390.1|WP_148562331.1|1018169_1019363_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961988.1|1002922_1006348_+|HNH-endonuclease	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|375896
NZ_CP012390.1|WP_158408640.1|1012568_1012721_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961994.1|1011515_1012205_-|TenA-family-protein	unknown	unknown	gnl|CDD|381693
NZ_CP012390.1|WP_053961983.1|996215_997040_-|peroxide-stress-protein-YaaA	unknown	unknown	gnl|CDD|234999
NZ_CP012390.1|WP_053961997.1|1015997_1017857_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP012390.1|WP_053961992.1|1010435_1010789_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_CP012390.1|WP_053961989.1|1006344_1007256_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|274694
NZ_CP012390.1|WP_053961993.1|1010969_1011371_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP012390.1|WP_053961988.1|1002922_1006348_+|HNH-endonuclease	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	2.2e-26	87.2	0.1
NZ_CP012390.1|WP_053961989.1|1006344_1007256_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	3.3e-74	244.2	0.0
NZ_CP012390.1|WP_053961990.1|1007259_1007580_+|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	3.5e-16	54.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012390.1|WP_053961982.1|993431_995141_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.08941e-43
NZ_CP012390.1|WP_053961995.1|1013396_1013888_+|hypothetical-protein	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	2.35128e-15
NZ_CP012390.1|WP_053961984.1|997129_997852_-|NAD(P)H-dependent-oxidoreductase	gnl|CDD|380324	cd02149, NfsB-like, nitroreductase similar to Escherichia coli NfsB. NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family includes FRase I in Vibrio fischeri, wihich reduces FMN into FMNH2 as part of the bioluminescent reaction. The family also includes oxygen-insensitive nitroreductases that use NADH or NADPH as an electron donor in the ping pong bi bi mechanism. This type of nitroreductase can be used in cancer chemotherapy to activate a range of prodrugs.	6.93861e-56
NZ_CP012390.1|WP_082345405.1|995393_996053_+|ribonuclease-HI	gnl|CDD|260010	cd09278, RNase_HI_prokaryote_like, RNase HI family found mainly in prokaryotes. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD), residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Prokaryotic RNase H varies greatly in domain structures and substrate specificities. Prokaryotes and some single-cell eukaryotes do not require RNase H for viability.	1.80177e-61
NZ_CP012390.1|WP_053961985.1|997896_999303_-|formate/nitrite-transporter-family-protein	gnl|CDD|376497	pfam01226, Form_Nir_trans, Formate/nitrite transporter.	1.32575e-46
NZ_CP012390.1|WP_053961991.1|1009696_1010323_-|NAD(P)H-binding-protein	gnl|CDD|225462	COG2910, COG2910, Putative NADH-flavin reductase [General function prediction only].	5.05155e-72
NZ_CP012390.1|WP_053961987.1|1001159_1002572_-|MFS-transporter	gnl|CDD|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.73528e-41
NZ_CP012390.1|WP_053961999.1|1019524_1020187_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	5.54947e-21
NZ_CP012390.1|WP_053961996.1|1014242_1015988_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.34297e-116
NZ_CP012390.1|WP_053961990.1|1007259_1007580_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.52612e-13
NZ_CP012390.1|WP_053961988.1|1002922_1006348_+|HNH-endonuclease	gnl|CDD|375896	pfam18470, Cas9_a, Cas9 alpha-helical lobe domain. This is an alpha-helical lobe domain found in Cas9 proteins. Cas9 enzymes adopt a bilobed architecture composed of a nuclease lobe containing juxtaposed RuvC and HNH nuclease domains and a variable alpha-helical lobe likely to be involved in nucleic acid binding. Amino acid residues located in both the nuclease and alpha-helical lobe clefts are highly conserved within type II-A Cas9 proteins.	1.93389e-43
NZ_CP012390.1|WP_053961994.1|1011515_1012205_-|TenA-family-protein	gnl|CDD|381693	cd19358, TenA_E_Spr0628-like, TenA_E proteins similar to Streptococcus pneumoniae Spr0628 and Saccharomyces cerevisiae S288C PET18. This family of TenA proteins belongs to the TenA_E class, and lacks the conserved active site Cys residue of the TenA_C class; most have a pair of structurally conserved Glu residues in the active site. TenA_C proteins (EC 3.5.99.2; aminopyrimidine aminohydrolase, also known as thiaminase II) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway; the role of TenA_E proteins is less clear. Arabidopsis thaliana TenA_E (not belonging to this family) hydrolyzes amino-HMP to AMP, and the N-formyl derivative of amino-HMP to amino-HMP. Members of this family include the putative thiaminase Streptococcus pneumoniae Spr0628, and Saccharomyces cerevisiae S288C PET18, a protein of unknown function whose expression is induced in the absence of thiamin. It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect. Many proteins in this family have yet to be characterized.	3.67858e-91
NZ_CP012390.1|WP_053961983.1|996215_997040_-|peroxide-stress-protein-YaaA	gnl|CDD|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	5.4435e-49
NZ_CP012390.1|WP_053961992.1|1010435_1010789_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.27179e-39
NZ_CP012390.1|WP_053961989.1|1006344_1007256_+|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	6.16944e-92
NZ_CP012390.1|WP_053961997.1|1015997_1017857_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.0037e-132

Protein sequences

>NZ_CP012390.1|WP_053961990.1|1007259_1007580_+|CRISPR-associated-endonuclease-Cas2
MSEQKVWSLVMFDVPTKTKTQVRAYTQLHKELLYLGFTHLQHSVYARYVPFVEPIAGIYKCIKAMCPPGGDIRMILISDSQWGKQVRIFNEEEEKPEDPPEQLEIF
>NZ_CP012390.1|WP_053961989.1|1006344_1007256_+|type-II-CRISPR-associated-endonuclease-Cas1
MTTNRWRIVDFSSFEGEVYYSGGQLTVVKEGKRKVKVPLVDVAVILIGPKTMVTGGTIDGVARNGCSLLVCDWKREPAAALHPWSFHTRVAARQRAQASLSVPRQKNAWKMLVQAKIRGQAHNLKAIDIKAAQHLEELAKSVHSGDPENVEGTAASYYWRRLFGPDYRRDANSRDNINGALNYAYTILRGHVMRSLTAAGLAPALGIHHKHRGNNFALADDLIEPFRPFVDYHVHTMVEGCTLTDLSIPETKRELVALTQGQFAPGGDTLPTVIQDLCTAFGQYVEGDIQTLPVLYWEGPFVE
>NZ_CP012390.1|WP_053961988.1|1002922_1006348_+|HNH-endonuclease
MRTTLDPIPTLPVEGSYVVGIDAGQNSVGLFALALTAEGVPHEILAMQSVIHDGGLDPDKAKSNQTRKASAGFARRARRRLRVEKKRLNKLDKLLDAQGWHGRQEAEFPTQIWEDRYRATSSYIEDDEERAQVLGEVFRHIARHRGWRNPYQPLADLFDDESQSDAFTRLVSNAQRVGARVDDSDTVGAIVWSALQCPHPVGLDPEDEARWANSNQLRIRTLGTESKKRPGLIDGRLFQVDNVHEIQRICATQNIPAELEEQLLGTIFDQNKASAGVMQTVGRCGLQPQLLRCSKAHPEFQRYRIAATLATLKIKEGHSARFLTAEERQKVAAELHNPHTTIATWGDVADLLGIEAPQLTGIASTTPDAELIVAARPPVDTTAIKMATKAKPFLKKWWNDAAPEQQQDFIELQVNYDTDSPDVNNYLLTLTPTELAEIETFSTKELPKGRASFAAETCRILADHLLNSDDSLADAIEMNFHRKPTVAQLTESTGIASVDRSLKIVSRFLQMARNYWGEPQAITVELAREGLMSAKAKADMEFQQRRARKARQTLQEKRGIREDNRRDTLRAEALHRQNNRCLYCGAPIDMHSVEMDHIVPRSGPGATNRVTNLAGSCHRCNQAKGGRTYAEWVKQDHPTYTNRKMVDDFVNHSMNLENQALPKKSMQKEYLRALHTVGKEDALDSRSLAPTATMGTILRGRLEAEFPETKVNVLAGFITAEARHAAGYWGLPTLHIEGDPHDNNKRIDRRHHAIDAAIMSITRPYTAQVLAQRKALRDQEKTLGSSYRSATVSNFYGSWKDFQGTDIAHKTAYQRWLSNSQVLIGLVAEKLLNDDIPVWTPLRLSRTSGRAHEDEIRPLAHRPVKAALTAKEIDASATEAQWCALTRCEDYDENTGLPENPERRIVINGTHLGPNDDLEFFTPKDNKKPDAICDQAALKVRDGWAAAGDFHHLRLYRIPQKKGFAYYFMRVLPFDLPTEGDLFSYELPPQSISIRQAHPKLKAALKKGEAVYLTWLVKNDVLEVDDKALGGIGKTLEEVIPNATRRWRVIGFDNSTTTIKLAPVLTSPEGVMSKQGGSSVDSRFDEATSRKLKQTVLAPNGWRPSAQVLMRGPLRVIRYDALGRERLSARSPLPFTLIIEP
>NZ_CP012390.1|WP_053961987.1|1001159_1002572_-|MFS-transporter
MKKTHLHVLLVVAVVLFALNMRAGVTSIAPVLQEIQGGLHMSDSLAGLLTSLPTLIFALVGLITPLASRTIGLHSTMLVAMVALSLGLIVRVFMGGSAGFLVFSIVALAGIAITNVLMPAFIKTHFPAQIPTYTAVYSTALTAMAFLSSVVVAPMSHSMSTGWRGALGFWGVLAVLAVVPAGILVALQKKHRLAVGDGAAAGDGTGAAAGDGVSYGAGASGAANADITADANAAAHTRAGAAGNTAAASAAVDADAANAADAAAGAEPAKLWVMFRSKKACALALFFGLQSLQAFVQMGWLAQIFRDYGVSQNYAGMLAGLMQLLSIPGAMLAPALLGKVKNPRLLVAGTAAIAAPAYLGMLLAPASVPWLWVILFALANTTFPMALTLIGWSGRSGDTTALLSSFVQSFGFLIASLGPLLVGILLQATTGWTVPLIFCLVLVIPFAIAGYMSAAPGYVDDQLTRTPAEA
>NZ_CP012390.1|WP_053961986.1|999505_1000750_-|hypothetical-protein
MHTDDEQLRSAYQQLNDAIEQAPQLFTDPTSYTLPASSLTSAQSFAAQLSTLVEHPYGAQAIMSWYFTATACLARFLGNLCGAIHDPNFDTSQGLAATYHQLVPLRHHSASTLTLLPLHDEPIGKDTPTLASHFAELDDAAIAATATTWCNAAAALHDYAARLHNAASSVAHAGTHAGAHARTHSADTFATSLAIHEWADGLEEFARRSETIAQRIDSFGATYATTRTQLADIADRRQEALEQPAFQTYTFPEAAFTSRVNQLLRGTYNPGIQQATLAGISFPLPQATHRKVKPGLTPHDYGYQPNTNPAANPAATPAAWPTPRTQSRDPYSPDLHNPVYDPKIREAYHNLFSEKRAPDPLATDGRNCAFRRRNPEDVPTFRRREPSSNRILPKPGGIRGPIRHPDDPLYGTGR
>NZ_CP012390.1|WP_053961985.1|997896_999303_-|formate/nitrite-transporter-family-protein
MGIIDGGKNSRANHQRAQIEERLTKNRERVQEERIATLNDDNTTFHREKALDDAFDRQVSEGRQRLARPRPQQFITGVMGGMEISLGILIGMRVTDLTSSQLLGGVAFSLGFITLLLAHSELFTEGFLVPTFAVVARRARIRQLIRFWFYTFLGNLVGGLVVMWATTTAFPDSNHVLIHHGEHFASLTPDLKTVLMAIIAGTAITLMTRMQMGTSEVVGKIVAALFGGILLFGFGMLHSVLDTLIMLGAWCAGSSVTPLDILGFLWWIIPLNMFGGIVCVAMPRALQARDRVRMERIRVALEMHNGDELANDARGLLISGHDLREELQKELEETSGETVPDGPWQDLGNRITARFTRLGNRLGSPDEQRQQSRRRQAEMDRRAKLTEQTMATRSRERQETQARADTANGNAASNGSGSGRGDGSSRKGDQSSTTLAERGSHHHSKGGSSSHNSSSPDSGGRIDPPLPR
>NZ_CP012390.1|WP_053961984.1|997129_997852_-|NAD(P)H-dependent-oxidoreductase
MSTDPTQHLPNQPGVPNLTPCMTAEQVVQLLHNRYTAKKYNPTMRVSEEDFAAIIEAGRMSPSSMGFEPWHFVRINNRNLINDMLPHMWGAVGKLEDASHFVALLGRNVDQMKPYSSYLTHIHEDVQKYPHEGLDARMDRYVTFINEDQDFQTDREKNLWVDKQVYMALGNMLTMSAAMGIDSTPIEGFQKRPLEELLTDRGVYDPEEFHLTVFVCFGYSDAEHRMKTRRPTSEVLTVID
>NZ_CP012390.1|WP_053961983.1|996215_997040_-|peroxide-stress-protein-YaaA
MRILLPPSEGKTPASPDRAPIRLDSLVYPHLADQRLAVGDALQAASNHPDALTILGAGQRVAGDVYRNRTLWQQPAAPARDIYTGVLYAGAQLSGGRPRHLAWADKHILIASGLWGWVRPGDRIPAYRCAMNVDLPGIGPLGPYWRRALKNTFTQQMEGELVVDCRSGAYQKAWMPNARVCQEYAIDVVQVKVVRLTNGREKVVSHNAKHWRGLLTQALVKAGGDGLTINDPGELVEAQPQLFATIRGSLGSDHLSGARLEGGDGCWTLTLITA
>NZ_CP012390.1|WP_082345405.1|995393_996053_+|ribonuclease-HI
MTIIAAADGSSLGNPGPAGWAWFIDETCWHAGGWPQGTNNQGELMAVLDLLLSTRHRAEEELHILCDSQYVINSLTKWMPGWKKRGWKKGDGKPVLNTDLMRQLDTELRGRPVRFTWVKGHAGHPLNEAADSAARAVATAYQHHQPIPEGPGFPGAGSTSAGNGSGSGAGSSAVRGGAAVTTPQSSPRHGAPSPTPNAAQNSAPTSTPSSAAGTQDTLF
>NZ_CP012390.1|WP_053961982.1|993431_995141_-|MFS-transporter
MTTTNTPKSTPKPVWAAVFVGLSTIIMTLDNTIVNVALSSIANYFNAPLSSAQWVINAYTLAFASLLLGVGAISDFWGRRPLFLIGHAFFMLSSLACAFAPTADSLVVFRGIQGFGAAMVFGTCIPLIADAYAKEDSARRNRAIGLSMTVSVAAMAFGPLVGGIILQTAGDFLGRGAWPWLFLINVPLGLICILGTLAAVPNTYKTLRAEGTTAQGKADYLTIVYTVISLFAINYAILYGPQRGWGSWRTILPFILGIIVMGIMIWRQSRKGDDALLNLNMFKIPSYSTVIVLGFVSKLMSFGLFSYCIYWMFGVGQRTPIQIGAIIMLVAVPMIAVAGMVGPLGKKIGANNVVAIGMAINAIGLLTGLSINYTTNWVAIVPVFLLMGIGGGFVTPFMMDIAVSVVPPQKAGVATGMANAAMPLGTAAGVAINGAILASHINNGLDKNSIFTSLPADTASTVRDMVSTGAADKVGAKVAGLLTADQATALNDLAIKLSSQGTAIIFVACGVATLLTVFLAKWGIRDSDRWHGDDTDGVADAPGDAMPGDAAADKTASAEVAAEESANTP
>NZ_CP012390.1|WP_053961991.1|1009696_1010323_-|NAD(P)H-binding-protein
MKIAVIGAHGKSGSLICEEATRRGHDVTAIVRRNDPVNAQATIVKDALDLYASDLAGFDVVVDALGFFTPETLPLHSTSLKHIADCLAGKNTRLLVVGGAGSLTVDDKGTTLDDTPEFPDDFKPLAKAMAKGLAELHERDDVNWTYLSPAADFQADGARTDRYAFAGEMLATNDKGESYLSYADMAQAMLDEAENGSHTRERISVYTK
>NZ_CP012390.1|WP_053961992.1|1010435_1010789_+|helix-turn-helix-transcriptional-regulator
MRDQKILSVAELPACPVETTLYLLGNKWKVLILRDLFDGPQRFSDLKRTVGTVSAKVLTSNLRSMEADRLLTRTVYAEVPPRVEYELTPLGYSLEPVISAMRNWGAAYKANRLSEDM
>NZ_CP012390.1|WP_053961993.1|1010969_1011371_+|hypothetical-protein
MYENVTQYIDEIAALDEDQLIPIVHEYIQQKRRLMPSGIVRGTHYEYNPLLWKPLNNWSKEHFMKTVADRTKGMRPEDFCTEEWLGNLDEDRVNLTLSWLVTNEDYYMGTLAEWVKNGTFLTLLRKLKEIDEA
>NZ_CP012390.1|WP_053961994.1|1011515_1012205_-|TenA-family-protein
MSRKLIDLVPGGHVEFLLASAREDWDAAVNHRFVDELFDGSLDDGVLAGYLVQDYQFFDAFLSMLGGCVAYADRVDSKLTFAAQLGMLADDEDGYFQKAFAELGVSEADQQDPPLTEVTKAFRAMMYDAANSQSYQDLLVMLVVAEWLYLDWGERGSTDNDPAPLPERYVHAGWVELHRGREFQKWCQFLVNELERVFPEDDESLADALTLRFQKAVALERGFFDVAYN
>NZ_CP012390.1|WP_158408640.1|1012568_1012721_-|hypothetical-protein
MNSTKEEKVMAFPGSRAWNAVRASLCWPRDTLLPLEVIRQAEDASENEAA
>NZ_CP012390.1|WP_053961995.1|1013396_1013888_+|hypothetical-protein
MDTTPAPLRQALLAINHQPTLLAATAERALLRTLHAGCELPIGAEATAQVHAQTRGVELTLRAEILSPDGRERNAAEHTVTIPQLLWAEESAEMAVAEIATAEAAAGLLAVVEVAGVSLATAPLAKDPGLVDPAYYAEAHEAQLAAAYQLGQMVAHRLKANAH
>NZ_CP012390.1|WP_053961996.1|1014242_1015988_-|ABC-transporter-ATP-binding-protein
MFKEMSRILGIQKGLTRIIVGFVLSGVFQAAAFIMLVPLLRHLFAQDWNGMWPWLGGVVAAGVLACIANISTTIFSYNLSTFDICGQSVERVGNKIFTLPLGWFDDRARGRISHALSYHVNNLSHYPSVALPAICNTLSMAGVMLLAGLVVNWQATLPFLLALPFCVWAFRHMLTDVDEEVNHHSDMERALTARSLEYAQAQPLLRASHRKQWKPLEDAIDTDSQAILEELTATSNVAKVYQLPLILACVVSLLVLGWQLASGYHGLGVQPVDVALFLAIAVLIVRMFIPLMQVVLNVAAITISREALLGLASILDAPGLPEPDPNQRMRIPGVDVQLDDVSFGYREDTPVLRDVNLYMPARTMTALVGPSGGGKSTIQRLIARFWDVNKGAVRIGGIDVRDVSTEELMQNLSIVFQETYLFNGTILENVRVGRPDASDEDVKEAARAACLDTVIESLPEGWDAMVGEGGSRLSGGERQRVAIARALLKKSPIVLLDEITSSLDGENEAAIVETLHRLSHNTTVIVIAHRLSTIKAADQIAVVANGGVEALGTHEELLAAGGTYAQFWEDQEFSQRWKLVD
>NZ_CP012390.1|WP_053961997.1|1015997_1017857_-|ABC-transporter-ATP-binding-protein
MRTTSTTTPREPKKPSPASVVLHPIRHEMAGIVTLAALGGVAEIGMYIALVEAARYIVTNHGLTSAGDPHFWWILAAALVCVLLRYFLIMGATGYAHVVEAKFRATIRRRILAKLDKLPLGWFDEQTSGRVRATINDAVTNIHTVVAHSAADLPNSLTTVIIGFIYLFVCDWRMTLVVLAYLVLVVLVSVLGFVLSDGNIMVEYTEAQKQLSESAVEIADGIAEVKNFGLTGQEFKRFEDASARYQKSLDDYMSGFGKPQGATTGLMIPGAMLIPLMVAGALMAWKGIVQPVDLMPFLLLGLGMPEAIGRLYTLTSYIFHGVSSISEIGTLLLEPDIEETDNPQPLTGNTIELKGVSFSYAAKPNEESADEADAALAVDTTATADSSATASARTEVLHDISLTMQPGTVTALVGPSGSGKTTITRLIARFWEPDSGTVEIDGVNICDVSTQELMHNMAIVFQDISLLSDTVTNNIRIARPDATQQEVIAAAKAARIHDRIMDLPQGYDTIVGSDSAYLSGGEQQRLTIARAFLQDAPIVLLDEATAYADPHSERAIQEALADLRGNRTVVVIAHRLHTIQDVDQIVVLNHGRIEATGTHSELLDTSPTYCGMWTAQQDA
>NZ_CP012390.1|WP_148562331.1|1018169_1019363_-|hypothetical-protein
MTTPTAASENRTVRATRAAVDTPASRHGGTLEPFPGVPSAACLGRTRRTGWARRGMAVVAALPLALTLAGTPQAAPQAAASPLSASVVDTGRATVTVPLQTTLLFTRSDMAPFTLRLSEFGDTDVPLKQNNKRPRGVWAQFQWVRMSTSSDGSGRWEDSPQRDVEKGDHNGAGRDQSPGDPNGAGRDQAGSSHRTGNSKYDGVERQSQLPRYRVTPVNLDPSDGPLPGYQFPLYESGSPYSPDRVVYTAAIQPGLVIVMEHLSLSGYNPTATLTLAQYAEHAPCRLDKFEFKRHTRVDLTLGPVGPTQVDVHQARGKMTLRGSHRRGGPLGLDVFIEEKVNGRECEAGFNPTLVKGDYAYINRVGRIRVEQIKDYPPSDPNLVGAPVGQAKLTLKTW
>NZ_CP012390.1|WP_053961999.1|1019524_1020187_+|class-I-SAM-dependent-methyltransferase
MSSVKSLFANFRLPADDPTGKKTLASMNKNHRKSNLWALKTLQSIVDARRGFTTNTILDVGCGGGQFLADLNIAWPDATLIGIDHSPAAIQATLDTNAHLVVSDKLTAYQATADTTLLDDNSVDIVTACETIYFWPDIDAALQEMRRILRPGGIFMVWVDGSNPIMMKPWEKLIGGMHTYTKAELRDVFTRNGFDTLQLAPPHQPPFYSRLATFGTAPAT

Crispr_ID: NZ_CP012390_4

• CRISPR_ID: NZ_CP012390_4
• CRISPR_location: 1020239-1020321
• CRISPR_type: orTypeII
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP012390_4

Consensus_repeat	Method
CCAAGTCCGCGGCTAAACCAGTGGGC	CRISPRCasFinder

spacers of NZ_CP012390_4

>4.1|1020265|31|NZ_CP012390|CRISPRCasFinder
CAGCCAAGCATCGCCCCCGCCGCCTGGCCCA

CRISPR arrays and Neighbor proteins around NZ_CP012390_4

CRISPR arrays

The CRISPR arrays of NZ_CP012390_4

>merge|NZ_CP012390|4|1020239-1020321|CRISPRCasFinder
CCAAGTCCGCGGCTAAACCAGTGGGCCAGCCAAGCATCGCCCCCGCCGCCTGGCCCACCAAGTCCGCGGCTAAACCAGCTGGG

>NZ_CP012390|4|4|1020239-1020321|CRISPRCasFinder
CCAAGTCCGCGGCTAAACCAGTGGGC	CAGCCAAGCATCGCCCCCGCCGCCTGGCCCA
CCAAGTCCGCGGCTAAACCAGCTGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012390.1|WP_053962007.1|1030443_1033050_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961996.1|1014242_1015988_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP012390.1|WP_158408641.1|1020678_1021407_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961993.1|1010969_1011371_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_148562334.1|1025880_1026087_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053961991.1|1009696_1010323_-|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|225462
NZ_CP012390.1|WP_082345597.1|1027381_1028914_-|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl|CDD|131739
NZ_CP012390.1|WP_053961994.1|1011515_1012205_-|TenA-family-protein	unknown	unknown	gnl|CDD|381693
NZ_CP012390.1|WP_053961999.1|1019524_1020187_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP012390.1|WP_082345598.1|1029509_1030406_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239645
NZ_CP012390.1|WP_158408642.1|1021754_1023197_+|hypothetical-protein	unknown	unknown	gnl|CDD|236138
NZ_CP012390.1|WP_053961992.1|1010435_1010789_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_CP012390.1|WP_053961995.1|1013396_1013888_+|hypothetical-protein	unknown	unknown	gnl|CDD|234612
NZ_CP012390.1|WP_158408640.1|1012568_1012721_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053978919.1|1026235_1026640_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053962002.1|1023422_1024406_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_158408643.1|1026737_1027385_-|YqgE/AlgH-family-protein	unknown	unknown	gnl|CDD|234694
NZ_CP012390.1|WP_148562331.1|1018169_1019363_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_063665753.1|1024594_1025653_+|bile-acid:sodium-symporter	unknown	unknown	gnl|CDD|372642
NZ_CP012390.1|WP_053961997.1|1015997_1017857_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012390.1|WP_053961992.1|1010435_1010789_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.27179e-39
NZ_CP012390.1|WP_053961996.1|1014242_1015988_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.34297e-116
NZ_CP012390.1|WP_158408642.1|1021754_1023197_+|hypothetical-protein	gnl|CDD|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	0.000196226
NZ_CP012390.1|WP_053961991.1|1009696_1010323_-|NAD(P)H-binding-protein	gnl|CDD|225462	COG2910, COG2910, Putative NADH-flavin reductase [General function prediction only].	5.05155e-72
NZ_CP012390.1|WP_053961994.1|1011515_1012205_-|TenA-family-protein	gnl|CDD|381693	cd19358, TenA_E_Spr0628-like, TenA_E proteins similar to Streptococcus pneumoniae Spr0628 and Saccharomyces cerevisiae S288C PET18. This family of TenA proteins belongs to the TenA_E class, and lacks the conserved active site Cys residue of the TenA_C class; most have a pair of structurally conserved Glu residues in the active site. TenA_C proteins (EC 3.5.99.2; aminopyrimidine aminohydrolase, also known as thiaminase II) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway; the role of TenA_E proteins is less clear. Arabidopsis thaliana TenA_E (not belonging to this family) hydrolyzes amino-HMP to AMP, and the N-formyl derivative of amino-HMP to amino-HMP. Members of this family include the putative thiaminase Streptococcus pneumoniae Spr0628, and Saccharomyces cerevisiae S288C PET18, a protein of unknown function whose expression is induced in the absence of thiamin. It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect. Many proteins in this family have yet to be characterized.	3.67858e-91
NZ_CP012390.1|WP_053961999.1|1019524_1020187_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	5.54947e-21
NZ_CP012390.1|WP_082345598.1|1029509_1030406_+|NUDIX-hydrolase	gnl|CDD|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	7.38755e-45
NZ_CP012390.1|WP_082345597.1|1027381_1028914_-|CCA-tRNA-nucleotidyltransferase	gnl|CDD|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	0
NZ_CP012390.1|WP_053961995.1|1013396_1013888_+|hypothetical-protein	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	2.35128e-15
NZ_CP012390.1|WP_158408643.1|1026737_1027385_-|YqgE/AlgH-family-protein	gnl|CDD|234694	PRK00228, PRK00228, YqgE/AlgH family protein.	1.63891e-46
NZ_CP012390.1|WP_063665753.1|1024594_1025653_+|bile-acid:sodium-symporter	gnl|CDD|372642	pfam13593, SBF_like, SBF-like CPA transporter family (DUF4137). These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.	2.88862e-93
NZ_CP012390.1|WP_053961997.1|1015997_1017857_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.0037e-132

Protein sequences

>NZ_CP012390.1|WP_053961999.1|1019524_1020187_+|class-I-SAM-dependent-methyltransferase
MSSVKSLFANFRLPADDPTGKKTLASMNKNHRKSNLWALKTLQSIVDARRGFTTNTILDVGCGGGQFLADLNIAWPDATLIGIDHSPAAIQATLDTNAHLVVSDKLTAYQATADTTLLDDNSVDIVTACETIYFWPDIDAALQEMRRILRPGGIFMVWVDGSNPIMMKPWEKLIGGMHTYTKAELRDVFTRNGFDTLQLAPPHQPPFYSRLATFGTAPAT
>NZ_CP012390.1|WP_148562331.1|1018169_1019363_-|hypothetical-protein
MTTPTAASENRTVRATRAAVDTPASRHGGTLEPFPGVPSAACLGRTRRTGWARRGMAVVAALPLALTLAGTPQAAPQAAASPLSASVVDTGRATVTVPLQTTLLFTRSDMAPFTLRLSEFGDTDVPLKQNNKRPRGVWAQFQWVRMSTSSDGSGRWEDSPQRDVEKGDHNGAGRDQSPGDPNGAGRDQAGSSHRTGNSKYDGVERQSQLPRYRVTPVNLDPSDGPLPGYQFPLYESGSPYSPDRVVYTAAIQPGLVIVMEHLSLSGYNPTATLTLAQYAEHAPCRLDKFEFKRHTRVDLTLGPVGPTQVDVHQARGKMTLRGSHRRGGPLGLDVFIEEKVNGRECEAGFNPTLVKGDYAYINRVGRIRVEQIKDYPPSDPNLVGAPVGQAKLTLKTW
>NZ_CP012390.1|WP_053961997.1|1015997_1017857_-|ABC-transporter-ATP-binding-protein
MRTTSTTTPREPKKPSPASVVLHPIRHEMAGIVTLAALGGVAEIGMYIALVEAARYIVTNHGLTSAGDPHFWWILAAALVCVLLRYFLIMGATGYAHVVEAKFRATIRRRILAKLDKLPLGWFDEQTSGRVRATINDAVTNIHTVVAHSAADLPNSLTTVIIGFIYLFVCDWRMTLVVLAYLVLVVLVSVLGFVLSDGNIMVEYTEAQKQLSESAVEIADGIAEVKNFGLTGQEFKRFEDASARYQKSLDDYMSGFGKPQGATTGLMIPGAMLIPLMVAGALMAWKGIVQPVDLMPFLLLGLGMPEAIGRLYTLTSYIFHGVSSISEIGTLLLEPDIEETDNPQPLTGNTIELKGVSFSYAAKPNEESADEADAALAVDTTATADSSATASARTEVLHDISLTMQPGTVTALVGPSGSGKTTITRLIARFWEPDSGTVEIDGVNICDVSTQELMHNMAIVFQDISLLSDTVTNNIRIARPDATQQEVIAAAKAARIHDRIMDLPQGYDTIVGSDSAYLSGGEQQRLTIARAFLQDAPIVLLDEATAYADPHSERAIQEALADLRGNRTVVVIAHRLHTIQDVDQIVVLNHGRIEATGTHSELLDTSPTYCGMWTAQQDA
>NZ_CP012390.1|WP_053961996.1|1014242_1015988_-|ABC-transporter-ATP-binding-protein
MFKEMSRILGIQKGLTRIIVGFVLSGVFQAAAFIMLVPLLRHLFAQDWNGMWPWLGGVVAAGVLACIANISTTIFSYNLSTFDICGQSVERVGNKIFTLPLGWFDDRARGRISHALSYHVNNLSHYPSVALPAICNTLSMAGVMLLAGLVVNWQATLPFLLALPFCVWAFRHMLTDVDEEVNHHSDMERALTARSLEYAQAQPLLRASHRKQWKPLEDAIDTDSQAILEELTATSNVAKVYQLPLILACVVSLLVLGWQLASGYHGLGVQPVDVALFLAIAVLIVRMFIPLMQVVLNVAAITISREALLGLASILDAPGLPEPDPNQRMRIPGVDVQLDDVSFGYREDTPVLRDVNLYMPARTMTALVGPSGGGKSTIQRLIARFWDVNKGAVRIGGIDVRDVSTEELMQNLSIVFQETYLFNGTILENVRVGRPDASDEDVKEAARAACLDTVIESLPEGWDAMVGEGGSRLSGGERQRVAIARALLKKSPIVLLDEITSSLDGENEAAIVETLHRLSHNTTVIVIAHRLSTIKAADQIAVVANGGVEALGTHEELLAAGGTYAQFWEDQEFSQRWKLVD
>NZ_CP012390.1|WP_053961995.1|1013396_1013888_+|hypothetical-protein
MDTTPAPLRQALLAINHQPTLLAATAERALLRTLHAGCELPIGAEATAQVHAQTRGVELTLRAEILSPDGRERNAAEHTVTIPQLLWAEESAEMAVAEIATAEAAAGLLAVVEVAGVSLATAPLAKDPGLVDPAYYAEAHEAQLAAAYQLGQMVAHRLKANAH
>NZ_CP012390.1|WP_158408640.1|1012568_1012721_-|hypothetical-protein
MNSTKEEKVMAFPGSRAWNAVRASLCWPRDTLLPLEVIRQAEDASENEAA
>NZ_CP012390.1|WP_053961994.1|1011515_1012205_-|TenA-family-protein
MSRKLIDLVPGGHVEFLLASAREDWDAAVNHRFVDELFDGSLDDGVLAGYLVQDYQFFDAFLSMLGGCVAYADRVDSKLTFAAQLGMLADDEDGYFQKAFAELGVSEADQQDPPLTEVTKAFRAMMYDAANSQSYQDLLVMLVVAEWLYLDWGERGSTDNDPAPLPERYVHAGWVELHRGREFQKWCQFLVNELERVFPEDDESLADALTLRFQKAVALERGFFDVAYN
>NZ_CP012390.1|WP_053961993.1|1010969_1011371_+|hypothetical-protein
MYENVTQYIDEIAALDEDQLIPIVHEYIQQKRRLMPSGIVRGTHYEYNPLLWKPLNNWSKEHFMKTVADRTKGMRPEDFCTEEWLGNLDEDRVNLTLSWLVTNEDYYMGTLAEWVKNGTFLTLLRKLKEIDEA
>NZ_CP012390.1|WP_053961992.1|1010435_1010789_+|helix-turn-helix-transcriptional-regulator
MRDQKILSVAELPACPVETTLYLLGNKWKVLILRDLFDGPQRFSDLKRTVGTVSAKVLTSNLRSMEADRLLTRTVYAEVPPRVEYELTPLGYSLEPVISAMRNWGAAYKANRLSEDM
>NZ_CP012390.1|WP_053961991.1|1009696_1010323_-|NAD(P)H-binding-protein
MKIAVIGAHGKSGSLICEEATRRGHDVTAIVRRNDPVNAQATIVKDALDLYASDLAGFDVVVDALGFFTPETLPLHSTSLKHIADCLAGKNTRLLVVGGAGSLTVDDKGTTLDDTPEFPDDFKPLAKAMAKGLAELHERDDVNWTYLSPAADFQADGARTDRYAFAGEMLATNDKGESYLSYADMAQAMLDEAENGSHTRERISVYTK
>NZ_CP012390.1|WP_158408641.1|1020678_1021407_+|hypothetical-protein
MLRVALTVERFSPMMSSFSLTSPGKKLTAVAFVCTVLGGLAGCNSQSVLNDNTSASWSSSSQRNPDHIYANHTEGADPDGGLGGFKSAQEYDDYKALSKKWGVKQTPDWLAICNQVNVSALRKVGFDPQKDLENRRGGTHKTNCYWSRNKDELQFFFGTTDSAERIKANPKFRYSTTVNRGKETYYMGDIQFLGEGTTVNQYSCSVTYERNGQAYMAAFTGKEPKTHDEACNELIDMVSPRN
>NZ_CP012390.1|WP_158408642.1|1021754_1023197_+|hypothetical-protein
MHKTCLPPDMGGLGHGVKLPDGRLVRSFSSRGIPLTEEPLGQDVDRLAVAFAKFDSSVFADCADAWTSAGETLVNLADDVQKIANDVQGAGSKDAYTYEAGSGIRRWAMSLRQLGKQANTVSKHIDTFAKNYDHARAEVNTVADESDWAKRNATEEHPYSPAVYTEKANTVLREHYNPELARADTKNIEIPVPIRAFHPDDTTRLPEPPKPIPVTPKGALTPPKIEANPVVAKSVLAQPVVPPPDTTDIPKATPGKGMPPAETTPNAAHPLPPSQGSGVGSVSGPTSMASGTTPSPATPAGTTTAGAAGSAGHPSAGYLGGYPSRWNNPHQSPHKNRESRPHTNLVVGAGAFGTGLSTGSSDRVVPKGGALRAIPGAGQTPGTSGTNPNTPTSSGTKAPAGSGSPAKSGTGTPTTSTGRPGTSGLPGTPGTGTSPNTTSKTTPRRTRRSAHNTERILPQPGNLPHGPIRHPNDPLYNTGH
>NZ_CP012390.1|WP_053962002.1|1023422_1024406_-|hypothetical-protein
MTRNFSKRLLALAAVVGVGVSLAPFTAANASAATVTKTILSNCRSNGAPAGQDETFAGDPDKMTITVPDQVKVGDEFKMVFDYVPAPVKGVDHGLTIKNYSNATYRFTIDDPSSFVTARFIGSGHATTGQPTISLVGGNRLVIGNINVDVNGKDIQRWGPPQVEVTFKATKPGKLPTLHAANEGAAAEFNNPENFFTVKNAVSAPVLGDFDLQVRCHSTMSKDTLASVDAVGSAADVKADDKKAGDKKANEKSSATNGDKSASSSSAASDGQLQITDTDVAADQDTGGSGTPGWLTALIVIIVLAIVGGGGYGIYKAVQKKKNNPNA
>NZ_CP012390.1|WP_063665753.1|1024594_1025653_+|bile-acid:sodium-symporter
MATPRSSSPSRFRLTLQRINKHIDWLIVGLLACILLATAFPAKEDFAIGMHYVSKVFLFLLFFFYGAKLAPRETLMGLRNWRLHVVITCFTFVVFPIIGIGLKYATIGWLGQGLALGLLYLTLVPGTVQSSIAFTSVAHGNVAGAIVSSSLSNVLGVFLTPLLVMLTMATTGDVHITGRSILDIFLQILLPFIIGQLLHKRLGPVLHRHPILTKTIDRGTIWVNVYTAFSEAVVQGVWVRVTMLHLLELIGICIAVVSLVLTLSWLLARALGFDRGDRIAAQFCGSKKSLSSGIAMGAVLFAGVGNGLSAGMLMLPLMLFHLFQLLICAVLAGRYGRQWERAHPDGVPAPPS
>NZ_CP012390.1|WP_148562334.1|1025880_1026087_-|hypothetical-protein
MPHPSNEKSTMQIDWNKVQDYGKALGSELLGDKYKDMPSTPEAARRKPTHTKREYFDAAVSLLKGKRK
>NZ_CP012390.1|WP_053978919.1|1026235_1026640_-|hypothetical-protein
MTKLLATYGAAAGLWLPSKVKPPCYSPPLSEVAMLHHTKAAAAVLAIGLAAAGIAGCHNDDNAPATTTNTTNPDGRVTVTKTVHPTDVARSNLNKATDKAKKDVDDLRKDANDTLKDVRDNFRETVTVTETPAP
>NZ_CP012390.1|WP_158408643.1|1026737_1027385_-|YqgE/AlgH-family-protein
MSDFQMNPYGNLSQFGAFADRIFLAMDQRDPYKGCLLVSAPDLRDEVFSRSVICLFEHDDTQGTFGIILNQQSEVSVHSVLPLFAPYCSKPASFFIGGPVETERVTGLLRLKPDCPVDLSLMHPVRGRTFLMDPTAHTIYRTQDIRESYRLYMGYCAWQPGQLAEEIAAGDWYVCDALDKDFATDHHTDLYAQVVRRQPWPLSLYASRPVDPRLN
>NZ_CP012390.1|WP_082345597.1|1027381_1028914_-|CCA-tRNA-nucleotidyltransferase
MHPTNQQQPTPAADTTSTPSAAAPASTVAGTSPTAEPDRTLRMLAAAQVQLHTLASTLTPLAAAFEAAGHDLYLVGGSVRDALLGQLGIDLDFTTDARPDAVTTILRNCTDNLWDTGIEYGTVSASKGGWQIEITTFRSDQYDGVSRNPTVHFGDTLEGDLIRRDFTVNAMALRLHGDGTQEFCDPLGGINDLAAGVLDTPQAPEVSFHDDPLRMIRACRFVSKLGFTLAPRVTAAIQDMSGEITRITAERIQAELDKLMLGTYPWDGIDLLCRTGLADHVFPEIPAMSMPPDPSLPHKDVYTHSLTVLKQACELEPGDPDLVLRWAALLHDVGKVPTRAAKPGGGVTFYQHEIVGARMVRKRFKALKYSRQMINDVSQLVYLHLRIHGYGDGEWTDSAVRRYVTDAGPLLDRLNFLVRADCTTARDWKRKKLHALVDSLEERIAELREKEDLEAIRPDLDGNEIMQILGLQPGPEVGQAWAFLKNLRMENGPMEHDQAVAALHEWWAAQ
>NZ_CP012390.1|WP_082345598.1|1029509_1030406_+|NUDIX-hydrolase
MRRAYNPRTNRVYLSAVKVALIGRTDRRGRLLWSLPKGHIEDYETVPMTAVREVREETGIEGEVIKHLGTIDYWFLSDGKRIHKTVHHYLLRFVGGELSNADAEISEVKWVSMKDLPAHLSYADERKLARRATGVVAAWIRSEYGSGDGTDETIQIEGEFPDDDILGDDLDAADLLEPTHGGKHTSDGQPAHGNQQHGNQQHGDGTQGDRAEGDRSTGDRAQGSRAGNSQHPRNSGRNSGQRRNRRGRRRGRRSNATTTNTTTANTGNHTPRTTPLTPNTGTPPPGNPHSLPNTPAHE
>NZ_CP012390.1|WP_053962007.1|1030443_1033050_+|hypothetical-protein
MTTPLRHRIAGLSLACCTLLAPAALAGATATAATTSYLSALDVTPNYGDTPPTHPPAYFADYTSPDSALLAAMSGHTNAALRTLTSDLSPVPDATPDALHISLTSITPNIIDGATSNHVTINGTLTNVGKLPISDIELRLQRGDYAPYSNALRHTLAEDQINYPTALPFHSLDATLQPGATTTFTLKARITGGTGDTLNIHAPGVYPLLINANGRVNNSDSARLHDARTLLPVLSLPHTTNHDPAETAPRPITLLWPLAITPQEASYYSFSSVTVLRDDNLGISLGKNGRLRTLLDTGATLLDDRTLGNSVCLAVDPDLLRTVNRMTRPYRVLNNPTNRHDGVHKGKHSSAAQAWLDHLRSLATNSCVIALPWAGASLAATTHSLGGALPHQLMADSRTVTAYILRTRLSSHVIWPNVGMVAAADLPAADHPELLLSSNALTGPSPYTRDAHHARALYQRNPKAPLRDVANSGYGQWFRSDGTTYTVTPFDSTLATALAATGHNPSNTLFGPSDSRYLLTADSATARMQDAVATLLWKTSANLRRENLATNSYPDAPLIIAPPQHWSVTDSELKTFTDTLRYLARRNLITTQSLTDALAQSKQMPRRGTLNTEQLTSMPLPDVPLATVTRAVTTINRYHNLFADKGDNNFYKRARYNIYRATTTRYWGISPTLVGNVPTTHNHRPNQHQDSPGIVLATPPMLGHPSAYARSIALAGQAMRSSVTLIKPASIYTLASTDSDLVLVARNELPADVTVTVHTLQRNGDGNGARTGQELAPARTITIPAQASLNVNIPVHLPSGQSVPVSVSLLSADGQELGTTVNMTVRVSRLTPLLGFFLFAAVAVLAFLILKRVLPLIRRSNGQGRSHE

Crispr_ID: NZ_CP012390_5

• CRISPR_ID: NZ_CP012390_5
• CRISPR_location: 1064867-1066055
• CRISPR_type: TypeI-E
• Repeat_type: I-E
• Spacer_info: 19 spacers
• Cas_protein_info: cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NZ_CP012390_5

Consensus_repeat	Method
GGCTCATCCCCGCTGGCGCGGGGCACAT	PILER-CR
GGCTCATCCCCGCTGGCGCGGGGCACAT	CRISPRCasFinder
GGCTCATCCCCGCTGGCGCGGGGCACAT	CRT

spacers of NZ_CP012390_5

>5.1|1064895|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
GTTTTTAGAGAGACAAAAAAGATTGATACCGCG
>5.2|1064956|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
GGCCGGGACATCAATAAAATCTAGACTTGTCCA
>5.3|1065017|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
CCGAGAAGGATTATATGTCGTCGCCTAACGGGC
>5.4|1065078|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
TACCGCTCGGTGGTGAAAGTCGCAGACGACGGC
>5.5|1065139|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
GCCGGGCTCAACATCCTCGATCGTCCCTCTACC
>5.6|1065200|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
GGCGGCTCGGTATCACTATTGACGAGGAAGAGC
>5.7|1065261|34|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
GGGGCCGGGCCGTACCCCACAAGGCAAACCTGAC
>5.8|1065323|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
AGATCTGTTTCCGTGGCCACCGACCCAGAAACA
>5.9|1065384|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
CCGGTCCATCTATATCGGGTGCCGGGATTGAAG
>5.10|1065445|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
TCATTGATGCATTTACCGGTACATAAACCGCCA
>5.11|1065506|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
AGTTCACTAGTTTTCTTCACTAAACTAGTTGAC
>5.12|1065567|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
GGGAACCCCGATCTACACGAATGGCCTTGCTGG
>5.13|1065628|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
CGCGTTGCCCTGGAAGTCGTACTGTGCGACTTC
>5.14|1065689|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
TGACGGCCATACCCCGGAGAGGGATGCGAATGC
>5.15|1065750|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
GTTTTTTCTTTTCCCCAGCCGTGGTCGAGTAGC
>5.16|1065811|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
GCGATCTTCGCCGGGGTCAGATAGCCACCATGC
>5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
CTCTACACGGTTGCTGGTGCCGCCGCCGCCGTC
>5.18|1065933|34|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
CTAGCGCTGTGGAGACGCTGAACCGCTACGCTGA
>5.19|1065995|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT
CTACGGAATCGACATATCTGAATGGCAGAACGG

CRISPR arrays and Neighbor proteins around NZ_CP012390_5

CRISPR arrays

The CRISPR arrays of NZ_CP012390_5

>merge|NZ_CP012390|5|1064867-1066055|PILER-CR,CRISPRCasFinder,CRT
GGCTCATCCCCGCTGGCGCGGGGCACATGTTTTTAGAGAGACAAAAAAGATTGATACCGCGGGCTCATCCCCGCTGGCGCGGGGCACATGGCCGGGACATCAATAAAATCTAGACTTGTCCAGGCTCATCCCCGCTGGCGCGGGGCACATCCGAGAAGGATTATATGTCGTCGCCTAACGGGCGGCTCATCCCCGCTGGCGCGGGGCACATTACCGCTCGGTGGTGAAAGTCGCAGACGACGGCGGCTCATCCCCGCTGGCGCGGGGCACATGCCGGGCTCAACATCCTCGATCGTCCCTCTACCGGCTCATCCCCGCTGGCGCGGGGCACATGGCGGCTCGGTATCACTATTGACGAGGAAGAGCGGCTCATCCCCGCTGGCGCGGGGCACATGGGGCCGGGCCGTACCCCACAAGGCAAACCTGACGGCTCATCCCCGCTGGCGCGGGGCACATAGATCTGTTTCCGTGGCCACCGACCCAGAAACAGGCTCATCCCCGCTGGCGCGGGGCACATCCGGTCCATCTATATCGGGTGCCGGGATTGAAGGGCTCATCCCCGCTGGCGCGGGGCACATTCATTGATGCATTTACCGGTACATAAACCGCCAGGCTCATCCCCGCTGGCGCGGGGCACATAGTTCACTAGTTTTCTTCACTAAACTAGTTGACGGCTCATCCCCGCTGGCGCGGGGCACATGGGAACCCCGATCTACACGAATGGCCTTGCTGGGGCTCATCCCCGCTGGCGCGGGGCACATCGCGTTGCCCTGGAAGTCGTACTGTGCGACTTCGGCTCATCCCCGCTGGCGCGGGGCACATTGACGGCCATACCCCGGAGAGGGATGCGAATGCGGCTCATCCCCGCTGGCGCGGGGCACATGTTTTTTCTTTTCCCCAGCCGTGGTCGAGTAGCGGCTCATCCCCGCTGGCGCGGGGCACATGCGATCTTCGCCGGGGTCAGATAGCCACCATGCGGCTCATCCCCGCTGGCGCGGGGCACATCTCTACACGGTTGCTGGTGCCGCCGCCGCCGTCGGCTCATCCCCGCTGGCGCGGGGCACATCTAGCGCTGTGGAGACGCTGAACCGCTACGCTGAGGCTCATCCCCGCTGGCGCGGGGCACATCTACGGAATCGACATATCTGAATGGCAGAACGGGGCTCATCCCCGCTGGCGCGGGGCACAT

>NZ_CP012390|5|3|1064867-1066055|PILER-CR
GGCTCATCCCCGCTGGCGCGGGGCACAT	GTTTTTAGAGAGACAAAAAAGATTGATACCGCG
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGCCGGGACATCAATAAAATCTAGACTTGTCCA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CCGAGAAGGATTATATGTCGTCGCCTAACGGGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	TACCGCTCGGTGGTGAAAGTCGCAGACGACGGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GCCGGGCTCAACATCCTCGATCGTCCCTCTACC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGCGGCTCGGTATCACTATTGACGAGGAAGAGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGGGCCGGGCCGTACCCCACAAGGCAAACCTGAC
GGCTCATCCCCGCTGGCGCGGGGCACAT	AGATCTGTTTCCGTGGCCACCGACCCAGAAACA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CCGGTCCATCTATATCGGGTGCCGGGATTGAAG
GGCTCATCCCCGCTGGCGCGGGGCACAT	TCATTGATGCATTTACCGGTACATAAACCGCCA
GGCTCATCCCCGCTGGCGCGGGGCACAT	AGTTCACTAGTTTTCTTCACTAAACTAGTTGAC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGGAACCCCGATCTACACGAATGGCCTTGCTGG
GGCTCATCCCCGCTGGCGCGGGGCACAT	CGCGTTGCCCTGGAAGTCGTACTGTGCGACTTC
GGCTCATCCCCGCTGGCGCGGGGCACAT	TGACGGCCATACCCCGGAGAGGGATGCGAATGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GTTTTTTCTTTTCCCCAGCCGTGGTCGAGTAGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GCGATCTTCGCCGGGGTCAGATAGCCACCATGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTCTACACGGTTGCTGGTGCCGCCGCCGCCGTC
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTAGCGCTGTGGAGACGCTGAACCGCTACGCTGA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTACGGAATCGACATATCTGAATGGCAGAACGG
GGCTCATCCCCGCTGGCGCGGGGCACAT

>NZ_CP012390|5|5|1064867-1066055|CRISPRCasFinder
GGCTCATCCCCGCTGGCGCGGGGCACAT	GTTTTTAGAGAGACAAAAAAGATTGATACCGCG
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGCCGGGACATCAATAAAATCTAGACTTGTCCA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CCGAGAAGGATTATATGTCGTCGCCTAACGGGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	TACCGCTCGGTGGTGAAAGTCGCAGACGACGGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GCCGGGCTCAACATCCTCGATCGTCCCTCTACC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGCGGCTCGGTATCACTATTGACGAGGAAGAGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGGGCCGGGCCGTACCCCACAAGGCAAACCTGAC
GGCTCATCCCCGCTGGCGCGGGGCACAT	AGATCTGTTTCCGTGGCCACCGACCCAGAAACA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CCGGTCCATCTATATCGGGTGCCGGGATTGAAG
GGCTCATCCCCGCTGGCGCGGGGCACAT	TCATTGATGCATTTACCGGTACATAAACCGCCA
GGCTCATCCCCGCTGGCGCGGGGCACAT	AGTTCACTAGTTTTCTTCACTAAACTAGTTGAC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGGAACCCCGATCTACACGAATGGCCTTGCTGG
GGCTCATCCCCGCTGGCGCGGGGCACAT	CGCGTTGCCCTGGAAGTCGTACTGTGCGACTTC
GGCTCATCCCCGCTGGCGCGGGGCACAT	TGACGGCCATACCCCGGAGAGGGATGCGAATGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GTTTTTTCTTTTCCCCAGCCGTGGTCGAGTAGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GCGATCTTCGCCGGGGTCAGATAGCCACCATGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTCTACACGGTTGCTGGTGCCGCCGCCGCCGTC
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTAGCGCTGTGGAGACGCTGAACCGCTACGCTGA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTACGGAATCGACATATCTGAATGGCAGAACGG
GGCTCATCCCCGCTGGCGCGGGGCACAT

>NZ_CP012390|5|2|1064867-1066055|CRT
GGCTCATCCCCGCTGGCGCGGGGCACAT	GTTTTTAGAGAGACAAAAAAGATTGATACCGCG
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGCCGGGACATCAATAAAATCTAGACTTGTCCA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CCGAGAAGGATTATATGTCGTCGCCTAACGGGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	TACCGCTCGGTGGTGAAAGTCGCAGACGACGGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GCCGGGCTCAACATCCTCGATCGTCCCTCTACC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGCGGCTCGGTATCACTATTGACGAGGAAGAGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGGGCCGGGCCGTACCCCACAAGGCAAACCTGAC
GGCTCATCCCCGCTGGCGCGGGGCACAT	AGATCTGTTTCCGTGGCCACCGACCCAGAAACA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CCGGTCCATCTATATCGGGTGCCGGGATTGAAG
GGCTCATCCCCGCTGGCGCGGGGCACAT	TCATTGATGCATTTACCGGTACATAAACCGCCA
GGCTCATCCCCGCTGGCGCGGGGCACAT	AGTTCACTAGTTTTCTTCACTAAACTAGTTGAC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GGGAACCCCGATCTACACGAATGGCCTTGCTGG
GGCTCATCCCCGCTGGCGCGGGGCACAT	CGCGTTGCCCTGGAAGTCGTACTGTGCGACTTC
GGCTCATCCCCGCTGGCGCGGGGCACAT	TGACGGCCATACCCCGGAGAGGGATGCGAATGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GTTTTTTCTTTTCCCCAGCCGTGGTCGAGTAGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	GCGATCTTCGCCGGGGTCAGATAGCCACCATGC
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTCTACACGGTTGCTGGTGCCGCCGCCGCCGTC
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTAGCGCTGTGGAGACGCTGAACCGCTACGCTGA
GGCTCATCCCCGCTGGCGCGGGGCACAT	CTACGGAATCGACATATCTGAATGGCAGAACGG
GGCTCATCCCCGCTGGCGCGGGGCACAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012390.1|WP_053962024.1|1062632_1063160_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NZ_CP012390.1|WP_053962021.1|1052976_1053606_+|DUF721-domain-containing-protein	unknown	unknown	gnl|CDD|179552
NZ_CP012390.1|WP_053962030.1|1070580_1072272_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl|CDD|378189
NZ_CP012390.1|WP_082345411.1|1066137_1066476_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
NZ_CP012390.1|WP_192839640.1|1066472_1067411_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693
NZ_CP012390.1|WP_158408644.1|1062360_1062534_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_082345412.1|1067410_1068079_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NZ_CP012390.1|WP_053962032.1|1076244_1076508_-|cell-division-protein-CrgA	unknown	unknown	gnl|CDD|178907
NZ_CP012390.1|WP_063665754.1|1051558_1052980_+|DNA-replication/repair-protein-RecF	unknown	unknown	gnl|CDD|234608
NZ_CP012390.1|WP_053962025.1|1063188_1063983_+|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|366759
NZ_CP012390.1|WP_148417656.1|1061826_1062102_-|hypothetical-protein	unknown	unknown	gnl|CDD|227160
NZ_CP012390.1|WP_053962023.1|1056009_1058493_+|DNA-gyrase-subunit-A	unknown	unknown	gnl|CDD|235502
NZ_CP012390.1|WP_053962026.1|1064131_1064554_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_082345413.1|1068075_1068786_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl|CDD|378243
NZ_CP012390.1|WP_053962029.1|1068790_1069924_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NZ_CP012390.1|WP_158408645.1|1064610_1064754_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_053962031.1|1075376_1075901_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_082345415.1|1069945_1070581_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
NZ_CP012390.1|WP_192839639.1|1053936_1055988_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl|CDD|235542
NZ_CP012390.1|WP_063665755.1|1072268_1075109_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP012390.1|WP_192839640.1|1066472_1067411_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	3.6e-103	339.0	0.1
NZ_CP012390.1|WP_082345413.1|1068075_1068786_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	4.8e-47	154.8	0.7
NZ_CP012390.1|WP_082345411.1|1066137_1066476_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.8e-28	93.2	0.0
NZ_CP012390.1|WP_053962029.1|1068790_1069924_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	4e-110	363.4	0.1
NZ_CP012390.1|WP_063665755.1|1072268_1075109_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.4e-62	205.9	0.0
NZ_CP012390.1|WP_082345412.1|1067410_1068079_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	2.7e-53	175.9	0.3
NZ_CP012390.1|WP_082345415.1|1069945_1070581_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	6.9e-25	82.6	0.0
NZ_CP012390.1|WP_053962030.1|1070580_1072272_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	4.3e-85	281.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012390.1|WP_053962021.1|1052976_1053606_+|DUF721-domain-containing-protein	gnl|CDD|179552	PRK03195, PRK03195, DUF721 family protein.	1.91774e-43
NZ_CP012390.1|WP_053962030.1|1070580_1072272_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	7.76244e-109
NZ_CP012390.1|WP_082345411.1|1066137_1066476_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	9.74605e-41
NZ_CP012390.1|WP_192839640.1|1066472_1067411_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	3.21157e-123
NZ_CP012390.1|WP_082345412.1|1067410_1068079_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	4.95647e-70
NZ_CP012390.1|WP_053962025.1|1063188_1063983_+|rhomboid-family-intramembrane-serine-protease	gnl|CDD|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	8.15425e-30
NZ_CP012390.1|WP_053962024.1|1062632_1063160_+|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	9.59225e-67
NZ_CP012390.1|WP_148417656.1|1061826_1062102_-|hypothetical-protein	gnl|CDD|227160	COG4823, AbiF, Abortive infection bacteriophage resistance protein [Defense mechanisms].	4.71458e-13
NZ_CP012390.1|WP_053962023.1|1056009_1058493_+|DNA-gyrase-subunit-A	gnl|CDD|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NZ_CP012390.1|WP_063665754.1|1051558_1052980_+|DNA-replication/repair-protein-RecF	gnl|CDD|234608	PRK00064, recF, recombination protein F; Reviewed.	7.21697e-137
NZ_CP012390.1|WP_082345413.1|1068075_1068786_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	7.48678e-45
NZ_CP012390.1|WP_053962029.1|1068790_1069924_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	2.48152e-165
NZ_CP012390.1|WP_053962032.1|1076244_1076508_-|cell-division-protein-CrgA	gnl|CDD|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	1.62978e-29
NZ_CP012390.1|WP_082345415.1|1069945_1070581_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	9.74486e-34
NZ_CP012390.1|WP_192839639.1|1053936_1055988_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl|CDD|235542	PRK05644, gyrB, DNA gyrase subunit B; Validated.	0
NZ_CP012390.1|WP_063665755.1|1072268_1075109_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	5.44864e-84

Protein sequences

>NZ_CP012390.1|WP_158408645.1|1064610_1064754_-|hypothetical-protein
MCAWNPQECTLAAFAHNIPAAIRPALMEALYKQCDFDNIARVLAPEN
>NZ_CP012390.1|WP_053962026.1|1064131_1064554_-|hypothetical-protein
MNINAEFRALKQLSGLTSQHIADKFDVGLRTAQRYETEYTPRSEIMEYLRSIVEDDTQYVEEVLDGIEADIHEANEQLGEVRNPGAVRLLRYLNSHYYYQANGVEAIPYERYTARLGRIISALILDGYEIEYEYYTTEEG
>NZ_CP012390.1|WP_053962025.1|1063188_1063983_+|rhomboid-family-intramembrane-serine-protease
MAATRRVDFATTFTKSPATWLLIIVNVALYLVVSAQGGTILNTAVSSPLLNDTVLVPYTLGFGQYWRLLTSGFMHFGLLHIVFNMYALWVLGRDVEGALGSLRFSAVYLLSLLAGSATVVWFSSPESATAGASGAIFGLLGAELVVVLALKAKLSGIITVIMLNVVIGITQPSISIQAHLGGFVVGFLVAGAFIFVPMWVAKSRQRRNKAGGVMLHPETGEEMPVYVTEKQVNAWGWGATAVVAVLVIIALVFGVENMQELIIR
>NZ_CP012390.1|WP_053962024.1|1062632_1063160_+|peptidylprolyl-isomerase
MSKATAQATLHTNKGDIVIDLFGNHAPKTVKNFIGLADGSAPYSTPNAKGAKEGPFYDGAIFHRIIDGFMIQGGDPTGTGTGGPGYRFEDEFTTELTFDRPYLLAMANAGPGTNGSQFFITVAPTPWLNMHHTIFGEVVDADSQAVVDALAKVATDMRDRPLEDVVIESIDVVEL
>NZ_CP012390.1|WP_158408644.1|1062360_1062534_-|hypothetical-protein
MKLKQVVNTFKKIAPLVPVFGGWKAATAVFALVQFGAPMLLRFLTNKKREMEANKAA
>NZ_CP012390.1|WP_148417656.1|1061826_1062102_-|hypothetical-protein
MTGSATHLDGSPGPVFVLRQRGMLVHQTKPFMTYTEQIELLRSRGMIIPDADKAQKFLERRNYYRLSGYWYPMRVFPDSTDRRVPVLPAWC
>NZ_CP012390.1|WP_053962023.1|1056009_1058493_+|DNA-gyrase-subunit-A
MSDNTTLPPDEATYDRVTPIDLNQEMQNSYIDYAMSVIVGRALPEARDGMKPVQRRILYAMFDSGFLHNRSYVKSARSVAETMGHYHPHGDYAIYDTLVRMAQPWTMRYPLVDGQGNFGSAGNDPAAAMRYTEARLTSLAEEMLRDIREDVVDFQPNYDGKTNEPVVLPSRVPQLLMNGSSGIAVGMATNIPPHNLGEIAEAIYWCLDNPDADEASTLEAVMERIKGPDFPTAGLIVGDQGIKDAYTTGRGSIRMRGKTSIEEEGKRTIIVITELPYQVNPDNLVSSIAQQVSDGRISGIANIEDQSSSRVGMRIVITLKRDAIAKVVLNNLYKHSALQTNFGANMLSIVDGVPRTLRIDQLVRIYVRHQLEVIIRRTRFRLRKKEERAHILRGLKKAIDMLDETIALIRRSPSADEARVGLMDLLEIDEAQANAILEMQLRRLAALELQKILDELAQIEIDIADLKDVLAKPERQRAIVKDELTDIVRKFGDERRTRIIPADGEISDEDLIPEEDVVVTITETGYAKRTKTDLYRSQKRGGKGVKGATLKQDEIVKHFFVCSTHDLILFFTTKGRVYRLKAYDLPEANRTARGQHVANLLAFQPGERIAQVIQLKSYQDAPYLVLATRNGLMKKSRLEDYDSNRTGGLVAINLKGDDELVGASLCSEDDDLILVSEYGQSIRFHATDDVLRPMGRATSGVYGMRFNGDDSLLSMNVVKENEFLLVATSGGYAKRTAMDDYPVQGRGGKGVLTIQYDRRRGNLVGAEVVSLDDEIFAITTGGGIIRTAAKEVRKAGRQTKGVRLMNLSDGDSLLAIARNADQEPEED
>NZ_CP012390.1|WP_192839639.1|1053936_1055988_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MRRPVAPSQKKKKNEYGADSITILEGLEAVRLRPGMYIGSTGERGLHHLVWEVVDNAVDEAMAGYCDEVNVTIMEDGGIEVRDNGRGIPVEMHASGAPTVQVVMTQLHAGGKFDSDTYAVSGGLHGVGISVVNALSTRVEAEIWRDGHHWIQNFNDAIPEDLVDDGHAEGRGTTVRFWADRNIFETTEYKFDIIARRLQEMAFLNKGLTITLEDQRVTREEAELDAEAESGDPELAVAAKSAEAEKAAATQKAVRRRKYHYPNGLRDYVESINKTKQALHPSIIAFDAKGEGHEVEIAMQWNNGYSESVHTFANTINTIEGGTHEEGFRSALTSLVNKYARDKKLIKDKDPNLTGDDIREGLAAVISVRVSNPQFEGQTKTKLGNTEVRSFVQRECNEHLGHWLEANPTEAKTIVNKAASSAHARLAARKARELVRRKSATDLGGLPGKLADCRSKDPAECEIYIVEGDSAGGSAKSGRDNYNQAILPLRGKILNVEKARIDRVLKNAEVQAIITALGTGIHDEFDISKLRYNKIVIMADADVDGQHIATLLLTLLFRFMRPLVEEGHVYLAQPPLYKLKWGKGEPGYAYSDRERDALLTAGLDAGRKINTDDGIQRYKGLGEMNDQELWETTMDPSTRTLRQVTLDDAAAADETFSILMGEDVTARRNFITRNAKDVRFLDI
>NZ_CP012390.1|WP_053962021.1|1052976_1053606_+|DUF721-domain-containing-protein
MSPNENFTSDAAHRTLAAALDAAQASGRNVGRGRASRPRSASAHPADPHAGTGQTSDISPSRDRASRGQRGAGSASTGRYRRYSWTSSGPDEWDPQLLTSLIADTVKKHGWQAEVTGGRIINNWPDIMGEEIASHSHVEKLDDEGTLHIRTDTTAWATQLRLLQPQILAELGKRYGSTVRMLRILGPNRPSWRKGPKHVKGRGPRDTYG
>NZ_CP012390.1|WP_063665754.1|1051558_1052980_+|DNA-replication/repair-protein-RecF
MFLRHCELHNFRSWDHLSLDLQPGITVFVGANGQGKTNFLEGINYLATLRSHRVSGDGPLIHEGADSAQLAATAVHNRRELTVALDIHTGKTNQATINTSPCRPRDILGVISTVLFAPEDLSLVRGDPAGRRAYLDDLLIQRCPRLRGVTNDYDKILRQRNALLKSASMALRHGYRTSAGASALATLDAWDAQLARVGAQLVAARLHLLRTIAPLVARNYAELAPHSRPVHLSYTSIPQITVEDCEAGLPLDMDYLEAALLAGLAEKRDREIERGITLAGPHRDDLTVLLGVQPAKGFASHGESWSLALALRLAAYDLLTADGTEPILLLDDVFAELDRYRREALAAVAAKAEQTLITAAVGEDLPTELHVAATHTVSTVGEASHRISLLDGILTDDPTLNEPDLAESGSAEPQPAVPGTVEAGSAESRSVKPGTVVPGSADRADPVQAGPTQTDAAQTHPAQVEQPEEVDGQ
>NZ_CP012390.1|WP_082345411.1|1066137_1066476_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MMVLVITACPAGLRGDLTKWVLEIAPGVFVGNPGGRIRDLLWERTTQLCRDGRALLVFSTNNEQHMEFRTHNHDWIPTDFDGITLMMRPDNKTTNNRPRNGWATARRLRKYR
>NZ_CP012390.1|WP_192839640.1|1066472_1067411_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MVKTPSQTPIERQALGRMENRISFLYIERAVVNRSGNALTITDERGTAHVPATQISVVLLGPGTKITHAAIALLGDAGTSTVWVGVNGVRYYAHGRSPARSSAMAEAQVKVWSNQRARLRCARRMYEMRFPNEDVSRLTMQQLRGREGYRVKNIYVREAARTGIPWDKRSYDPHDFDTGDDINKALSEGAAALYGVAYAVITGLGFIPSLGIVHTGTDSSFVYDIADLYKAEISIPAAFEATAQTWAGEPVSVRHVIRDKIVSTRLIPRMIHDLQELMNIPEELSTDCGDLFLWDELQAVPAGVNYEEQTAS
>NZ_CP012390.1|WP_082345412.1|1067410_1068079_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTTFTRVLLNERRRGGRHLLLNPEAMHAAISAAFPPDTSKEHGRILWRVDHHKAKHEHVLYIVGPEKPTVEHIVEQAGWDTRPGQIADYDRFIHAIQNGQQWHFELVANPTKSVPQSRGTRGKVVPLTTVNTQLNWLLENAPRHGFSVSSDDIVTARVIESHLLSFQRNSHQSRNMVRITTARFEGELTVVDAAALRHTLMNGIGRARGYGCGLLTLAQRDS
>NZ_CP012390.1|WP_082345413.1|1068075_1068786_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSSFSLLLLLRGPMQSWGDESRYTTRATATTPSKSGVIGLLAAAEGRRRSDPIEDLTKLKLAVRVDQSGTLLRDYQTAQPWQINPQANATLVTRYFLSDASFLVAIESPHREILEGLAHALNHPAFPLFLGRRSCPVSADLVQGIVDEPAVQALHNHEKWHASTAYKKSRSRHVKLPIYRDAEPGEIGDLRHDVPLSFSSEHRQYGWRTVIEDAPKIVVNELGTEHDPFFEAVISV
>NZ_CP012390.1|WP_053962029.1|1068790_1069924_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTLIVDIHALHTVPPSLINRDDTGAPKTAVFGGVPRQRVSSQSWKRAIRQYMEQNIDSSLVGFRSKKLPGKIAELVQEQNPGWPVEQVIQGVENLFKAAGIKLEKPKKSASTEDDCSGGESYPETGYLLFLSPHQITCAAEIISQNHGEKIDKKDAKSILDTEHSVDVAMFGRMLADAPSYNVDAAVQVAHAISVHGTEPEFDYFTAVDDIVEDAEEAGAGMIGTVQMMSSTLYRYATINVDGLAHNLGSKDAASEAVGYFLQAFTESLPTGKINTFANQTLPELVYVAIRDTRPVSLVNAFEEAVTSDEREGKNRREVAAEKMAQEEKHVEETYGFVPKASFVVALGTLGSSFAELSTSTTMTTLSAQVQEALRAE
>NZ_CP012390.1|WP_082345415.1|1069945_1070581_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSDDYTSAYRTAPLRVAVDATCTHLQKDYLGNAGDARMHSSRAILASLRRVSTLEPSKYPLEFENVLMTLNPRLEEKALGRGDSPSPSERAAFAAMTLFSIHMESATSPMHNPRVSFATACGMLIGLNESASIKPRVDAMLLAGNENSRMIHMRSLINLLRRREIPCDYGSLAEDLRRLSYTKSRPGVQLRWGRDIATGVYRASQTNSTHQ
>NZ_CP012390.1|WP_053962030.1|1070580_1072272_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNYSLLSEPWVKGEDSAGNPVTSGIRDIFTGESTMVRLQGDSPAQDYAILRLLLAIFWRAHHPETHVSHGDTFDFGMWFEETWLRLKEEKADRCVVEYLAQFEDRFDLLHPTMPFMQVADLHTANDDSKPVGLLMPEINSDYFTMRAGERKHYLTLDEAARWLVYTQAFDFSGIKSGAVGDSRVKGGKGYPIGQGWSGLTGGTVVVGVDLFETFLLNTTASALYGKDDHPVWERIPDGPGARAEHSPTHMWPVSPAEPQGPADLATWQSRRIRLFFEEEDRVSRVLISNGDRIPDAGANILADPMTPYRFSTNKSKKGYDVYYPRPYDSERTVWRSLDALLIAEGDTFEGRGKPPQQPRILTSLAELSSELDEIPHVLDVKLVSLAYGPQAASVTNTVSTSMGIPTALLTSNSAESRNAVRRSALATKDAAVALGSYAGMLLVAAGGEYSFQSSPTDCVLAILEPLFTEWLRNLHANSFDEVIEATAHWEKIVRHYLEDQAKILLRGAGPKALVGVVDATTGSITSAGTCYRQLAGRLNKILPSTAPEKKPHGHTSDRKDGIS
>NZ_CP012390.1|WP_063665755.1|1072268_1075109_-|CRISPR-associated-helicase/endonuclease-Cas3
MVTKHFYLQFAEDENDWVQSCSPQARAIWAKTGEEGAWLNLPQHLLDAACVAAYLWEKWVAPSIKKKLSELLSLSEDDCRALYIFLSGVHDVGKATITFVRQIEDRVDYQHLFTTMSKHGLRLENSAETLFISIHDRLPHSVASGHIVSQWLQERGVKKRLANSLSYVVDAHHGMTSNSGLREDAESIFSSYPEEWAAIHHELIEGMADISGIGPLLETFSSQRIRLMADSEELLTGLIVMADWIASNQDYFPLHEEGTQLERLRRAVKCVDLTGSWQLQKFPTEVDQLFRQSFGWPTTMCPRPVQIAAVNMARSSGSPFLMLIEAATGEGKTEAGLAAASIAGVQQGSQGIFFAAPTMSTANGLFQRTVDWTRYSTVSNSVTSLYLAHSRNKLSSLYRSLRHGYTSIGIDEAEGGSVIASQWMSGNKKGILSNIVVGTIDQVLALSLQMRHSMLRHIGLAGKIIIIDEVHSYDAYMSSYLATTVQWLARYGTSIIMMSATLPPEQKKALVEAYAEEGCREPLRSDEYTMLDNEAYPLITIVNEEGVRIQEVPSRRTDMEAQLTLIDDALETVADLLEDSLSDGGIALVICNTIRRAQDLFRKLTSAFPEEVELHHSAFTATARSAKEDRLRDILGPHQHRGTGRPDRLVIVSTQVAEQSLDIDADVLITDIAPMDLLIQRAGRLFRHQRPMSDRPLKLQSPTIYIRGIKEEKPVPLFDTGTEAVYDKKLLMTTYLHIPQVFHRPDDISPLVRSVYKEEQDMPEEWQEAWEKSRASSDAQRDRAESRASTFRIPRPRESSHLPSLFGQLISPNNARRSEEEGYAQVRDAEPAIEAIAIQQDRNGGYGPMDEPWIEEIFDTSELSFRQALQLAGVTLRLPAWMTRRDADFEEVITDLENMTPTSWAQQPLLKGKVALRFNEERTARVGQFDVIYSSDLGLEVERVMK
>NZ_CP012390.1|WP_053962031.1|1075376_1075901_-|hypothetical-protein
MPSDTPIRYEWSPNIAWRIAGIVVGAFLFALSFMPNVSTGGKILLILAAFTVVWNGLAGLIRRPRLVITDTDLHVRRTFRDHVYPLYSIHGFRIDRPSGIIQRFPMLTFDIARVEDWADLRTEFEHQHTLPLPLPAMENRQRDTLEVLTWGDIGVNPLGIATDLEEAGIRNLNN
>NZ_CP012390.1|WP_053962032.1|1076244_1076508_-|cell-division-protein-CrgA
MPKSKVTKTDLSEGVSRTPVKVKQATTPIVWLVIMGICLVLGLVWIVVYYLVAGRGIIPFVDTLGAWNYAIAFGLMVIGLLMTLRWR

Crispr_ID: NZ_CP012390_6

• CRISPR_ID: NZ_CP012390_6
• CRISPR_location: 1683496-1683691
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP012390_6

Consensus_repeat	Method
CCTGCCCCCACTGTGGCGGCACCGG	CRISPRCasFinder

spacers of NZ_CP012390_6

>6.1|1683521|26|NZ_CP012390|CRISPRCasFinder
ATCAGAATCCGGAGCCCAGCCCGAAA
>6.2|1683572|53|NZ_CP012390|CRISPRCasFinder
CCAAATTCAAGACGTTCAACAGTCCTTCCTCGGGCAAATCGTCACCACCCACG
>6.3|1683650|17|NZ_CP012390|CRISPRCasFinder
ACAGATCATTGCCGACC

CRISPR arrays and Neighbor proteins around NZ_CP012390_6

CRISPR arrays

The CRISPR arrays of NZ_CP012390_6

>merge|NZ_CP012390|6|1683496-1683691|CRISPRCasFinder
TCTGCCCCGACTGCCAAGGCACCGGATCAGAATCCGGAGCCCAGCCCGAAACCTGCCCCCACTGTGGCGGCACCGGCCAAATTCAAGACGTTCAACAGTCCTTCCTCGGGCAAATCGTCACCACCCACGCCTGCCCTCACTGTGGCGGCACCGGACAGATCATTGCCGACCCCTGCCGCACCTGTGACGGCGGTGG

>NZ_CP012390|6|6|1683496-1683691|CRISPRCasFinder
TCTGCCCCGACTGCCAAGGCACCGG	ATCAGAATCCGGAGCCCAGCCCGAAA
CCTGCCCCCACTGTGGCGGCACCGG	CCAAATTCAAGACGTTCAACAGTCCTTCCTCGGGCAAATCGTCACCACCCACG
CCTGCCCTCACTGTGGCGGCACCGG	ACAGATCATTGCCGACC
CCTGCCGCACCTGTGACGGCGGTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012390.1|WP_053962428.1|1672183_1673146_+|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl|CDD|236130
NZ_CP012390.1|WP_053962437.1|1684229_1684985_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl|CDD|236959
NZ_CP012390.1|WP_172621866.1|1691135_1692527_+|glycine--tRNA-ligase	unknown	unknown	gnl|CDD|235240
NZ_CP012390.1|WP_053962431.1|1674485_1676342_+|elongation-factor-4	unknown	unknown	gnl|CDD|235462
NZ_CP012390.1|WP_158408654.1|1670013_1672179_+|ComEC/Rec2-family-competence-protein	unknown	unknown	gnl|CDD|377126
NZ_CP012390.1|WP_063665785.1|1685002_1686049_+|PhoH-family-protein	unknown	unknown	gnl|CDD|376820
NZ_CP012390.1|WP_053962439.1|1686544_1687897_+|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NZ_CP012390.1|WP_053962751.1|1689783_1690560_+|isoprenyl-transferase	unknown	unknown	gnl|CDD|237826
NZ_CP012390.1|WP_053962429.1|1673290_1673551_-|30S-ribosomal-protein-S20	unknown	unknown	gnl|CDD|178943
NZ_CP012390.1|WP_053962434.1|1680260_1680542_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP012390.1|WP_063665786.1|1692638_1693511_+|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl|CDD|225415
NZ_CP012390.1|WP_053962440.1|1687889_1688816_+|GTPase-Era	unknown	unknown	gnl|CDD|234624
NZ_CP012390.1|WP_082345629.1|1678147_1680142_+|M3-family-metallopeptidase	unknown	unknown	gnl|CDD|341051
NZ_CP012390.1|WP_053962430.1|1673740_1674313_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl|CDD|367091
NZ_CP012390.1|WP_053962438.1|1686052_1686523_+|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl|CDD|234575
NZ_CP012390.1|WP_053962432.1|1676378_1677935_-|carboxylesterase/lipase-family-protein	unknown	unknown	gnl|CDD|225181
NZ_CP012390.1|WP_082345516.1|1680544_1681783_+|coproporphyrinogen-III-oxidase	unknown	unknown	gnl|CDD|180172
NZ_CP012390.1|WP_053962435.1|1681914_1682955_+|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl|CDD|234621
NZ_CP012390.1|WP_053962441.1|1688818_1689583_+|DNA-repair-protein-RecO	unknown	unknown	gnl|CDD|234622
NZ_CP012390.1|WP_082345518.1|1690588_1690951_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP012390.1|WP_082345518.1|1690588_1690951_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	6.1e-16	53.6	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012390.1|WP_053962428.1|1672183_1673146_+|DNA-polymerase-III-subunit-delta	gnl|CDD|236130	PRK07914, PRK07914, hypothetical protein; Reviewed.	6.71846e-129
NZ_CP012390.1|WP_053962437.1|1684229_1684985_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl|CDD|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	3.21099e-70
NZ_CP012390.1|WP_172621866.1|1691135_1692527_+|glycine--tRNA-ligase	gnl|CDD|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0
NZ_CP012390.1|WP_053962431.1|1674485_1676342_+|elongation-factor-4	gnl|CDD|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP012390.1|WP_158408654.1|1670013_1672179_+|ComEC/Rec2-family-competence-protein	gnl|CDD|377126	pfam03772, Competence, Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane. These proteins contain a highly conserved motif in the amino terminal transmembrane region that has two histidines that may form a metal binding site.	5.21005e-36
NZ_CP012390.1|WP_053962441.1|1688818_1689583_+|DNA-repair-protein-RecO	gnl|CDD|234622	PRK00085, recO, DNA repair protein RecO; Reviewed.	6.24979e-77
NZ_CP012390.1|WP_053962439.1|1686544_1687897_+|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.43731e-99
NZ_CP012390.1|WP_053962432.1|1676378_1677935_-|carboxylesterase/lipase-family-protein	gnl|CDD|225181	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism].	5.57965e-84
NZ_CP012390.1|WP_053962751.1|1689783_1690560_+|isoprenyl-transferase	gnl|CDD|237826	PRK14829, PRK14829, undecaprenyl pyrophosphate synthase; Provisional.	2.11951e-141
NZ_CP012390.1|WP_053962429.1|1673290_1673551_-|30S-ribosomal-protein-S20	gnl|CDD|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	3.22772e-26
NZ_CP012390.1|WP_063665786.1|1692638_1693511_+|trimeric-intracellular-cation-channel-family-protein	gnl|CDD|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	4.03848e-43
NZ_CP012390.1|WP_053962440.1|1687889_1688816_+|GTPase-Era	gnl|CDD|234624	PRK00089, era, GTPase Era; Reviewed.	4.51687e-153
NZ_CP012390.1|WP_063665785.1|1685002_1686049_+|PhoH-family-protein	gnl|CDD|376820	pfam02562, PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.	6.84761e-133
NZ_CP012390.1|WP_053962430.1|1673740_1674313_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl|CDD|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	1.20551e-11
NZ_CP012390.1|WP_053962438.1|1686052_1686523_+|rRNA-maturation-RNase-YbeY	gnl|CDD|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	6.19791e-69
NZ_CP012390.1|WP_082345629.1|1678147_1680142_+|M3-family-metallopeptidase	gnl|CDD|341051	cd06456, M3A_DCP, Peptidase family M3, dipeptidyl carboxypeptidase (DCP). Peptidase family M3 dipeptidyl carboxypeptidase (DCP; Dcp II; peptidyl dipeptidase; EC 3.4.15.5). This metal-binding M3A family also includes oligopeptidase A (OpdA; EC 3.4.24.70). DCP cleaves dipeptides off the C-termini of various peptides and proteins, the smallest substrate being N-blocked tripeptides and unblocked tetrapeptides. DCP from Escherichia coli is inhibited by the anti-hypertensive drug captopril, an inhibitor of the mammalian angiotensin converting enzyme (ACE, also called peptidyl dipeptidase A). OpdA may play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. It can also cleave N-acetyl-L-Ala. This family also includes Arabidopsis thaliana organellar oligopeptidase OOP (At5g65620), which plays a role in targeting peptide degradation in mitochondria and chloroplasts; it degrades peptide substrates that are between 8 to 23 amino acid residues, and shows a weak preference for hydrophobic residues (F/L) at the P1 position.	0
NZ_CP012390.1|WP_082345516.1|1680544_1681783_+|coproporphyrinogen-III-oxidase	gnl|CDD|180172	PRK05628, PRK05628, coproporphyrinogen III oxidase; Validated.	0
NZ_CP012390.1|WP_053962435.1|1681914_1682955_+|heat-inducible-transcriptional-repressor-HrcA	gnl|CDD|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	1.84865e-134
NZ_CP012390.1|WP_082345518.1|1690588_1690951_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	3.01797e-17

Protein sequences

>NZ_CP012390.1|WP_053962435.1|1681914_1682955_+|heat-inducible-transcriptional-repressor-HrcA
MARADERRLKVLRAIVTDFVASHEPVGSKALVEKYQLGVSSATIRNDMAVLEAQGYITQPHPSSGRVPTEKGYREFVDNIEQIKPLSRAERTAIRRFLDNSISIDDVLNRGIRLLSQLTQQVAVIQYPTLHCASVQHVEIIQMADRRVLVVIITDRGRVDQRIVEFDRDLTPDAVTTLQQEFITALKCRTLSEASTAVAALLADPHHPYAKELARAGHIILDTLVEHPEERLLLGGTSHLTRHASSFHGSLQELLDALEEQVVILKLLNSAATNPLGDPHAVTVRIGEETHLEHIHGTSVVSTTYGTDDSVFGGLGVIGPTRMDYLTNIAAVSAVARYIGEILAGH
>NZ_CP012390.1|WP_082345516.1|1680544_1681783_+|coproporphyrinogen-III-oxidase
MPSSAHTPTDAPTPQVPWECVDRQALATRPFGIYLHVPFCTSRCGYCDFNTYALHTFPAGPTGDPITTWADQLCHEIRLGAQLLADRGVTPPPASTVFFGGGTPSLLGDRLPAILAVVRECCGIAPGAEITSEANPESTSPELFECWRKAGVNRLSLGMQSSSPQVLALLDRNHDPTRAVSAIREAQAVGFEHLNLDLIYGTPGETADDVTRSVETVVETGVDHVSAYALTVEPGTALFRKIVRGEIAPVDEDVQADRYYQIDAALQQAGFAWYEVSNWARSHEARCRHNLGYWEGGNWWAAGPGAHGYLGGVRWSIRKNPRSYGALLAHGIYPADWCEVLTAEELREETIMLRLRVRDGLHRSVLTPAQAQVAATAVGDGLATWEGEYLVLTTRGRLLADGVIGDLLLVDD
>NZ_CP012390.1|WP_053962434.1|1680260_1680542_+|hypothetical-protein
MERFIDWTNTVASWFVDLPVGWQMFFALLILIPICLVIAKFLLLPIIDAVQNAYRRRVDVHNVIEPAVVENVDESATTAAGVAADGTAHSDSR
>NZ_CP012390.1|WP_082345629.1|1678147_1680142_+|M3-family-metallopeptidase
MPALEEALRRHSVEIAAIADSPDAPTAANTVVALERSGQDLARVLGYFFTVAGADATDERLRMEAEIAPLIAQHSDDMYMNPQLFRRIDAVFQALPESLGRIEVKGQVTAAQLDAETVALVQRYHDLFLRHGAGLAEEAQARIREINAELSQLSSEFGDNLLTDTQLRAVHITEESELAGVADAQKSFFAETARAAGKTGWLVPLGLPTAQPILEQLSDPAVRARVYEASLQRGGRRSEQIAHRMAVLRAEKATLFGYHTFAEFVISDETAGTPEAALELLSDLAPAAVRNAESERKDLVAMAEAAGDTSFTAADWPYYAEKVRAAHYALDSAMLKPYFRLQSVVEKGVFRAAETLYGLRIVKRSDLVGYTPDTDVWEVTDAETGEGIALLLTDYFTRPTKRGGAWMNSIVDQNYLLGQKPIIINVLNLTPAPAGEEVLLTLDEVETLFHEFGHALHGMLSSVVYPLFSGTNVPRDFVEFPSQFNEMWTLHEDTLPVYAHSAAGETIPSELVQKVRAAQQFGQGFATVEYLAACIIDMAWHTLTHAEALALGDDLDVAAFERAALQRAGLLVDGVAPRYRTRYYQHIFSNGYSAGYYSYLWSEVLDADTVDWFNEQGGLVPEAGRRFREKILSRGGAIDYMAAYRDFRGRDKDVTPLLRRRGLV
>NZ_CP012390.1|WP_053962432.1|1676378_1677935_-|carboxylesterase/lipase-family-protein
MAENDTTTVTSPRGVPSPFVVTTRSGQVQGLDRTHDVVFYSIPYAAPLSGISRFAKPEPPLPWDGIRDCTAPGSTAQDFSTTPNPTIPEVVRPGAEKLNLTIYAPKDALPQPGKLPLAHPLPVFVWIHGGSFIVGENACDWWDGAKFTAAGVIVVTINYRLDAEGWLPLPDAPQNRGMLDQLAALQWVQRNISAFGGDPQRVTIGGQSAGGTSALCLASNPAAQGLFQQVFSCSPAFVRLPADGGAKGIVKAARRAMPFRTFTADALSQWPLQKMEKLSLRMRRSNPLGLPFYPVRDKATQPQSLTDAADSALFQHYPMLIGSTSEEFDSVTFNGALKLLSRLGVEISLSTAGVDPSRRNSVIAAHHDDIHEGRVGAVMSDTMIRATVATAIEGRVLDQPAEESRTWVYDYRWPGRQGAAHCADLPIWFGTLGAKTANNVVGPVTTTDPSDPTAAVLDDAAGQTTADLMHSALQHFIADGNPGWPTYNETTRVCMVWDEKPHVEMDCYRAARSTWGLS
>NZ_CP012390.1|WP_053962431.1|1674485_1676342_+|elongation-factor-4
MAHFAETTFTDPARIRNFCIIAHIDHGKSTLADRMLQITGVVNQREMRDQYLDRMDIERERGITIKAQNVRIPWVPKTGTCAGQEIVMHLIDTPGHVDFTYEVSRALEACEGAVLLVDAAQGIEAQTLANLYMAIDKDLEIIPVLNKIDLPAADPDRYAREIAQIIGCDPSDVIQVSAKSGIGVEELMDVIAEKVPAPTGSSSGPTRALIFDSVYDIYRGVVTYIRVMDGEIRPRTKIRMMSTGAVHELLEVGVISPEPKPTDGLGAGEVGYLITGVKDVRQSKVGDTVTTFKDGAEEPLAGYEDPKPMVYSGLYPIDASDYPDLRDALDKLQLNDAALTYEPETSVALGFGFRCGFLGLLHMEITRDRLQREFGLDLISTTPNVHYRVVTEDGTEYEVTNPSNWPEGKLREVNEPVVSSSIIVPSEFVGTTMELCQTHRGELKGMDYLSETRVELRYRLPLAEIIFDFFDSLKSRTRGYASLDYHEDGEQLSDLVKVDILLQGEAVDAFSAIVHKDYASTYGNMMTKKLRALIPRQQFEVPIQAAVGSRIIARENIRAIRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKTIGRVDVPQEAFIAALSADAESDKKKN
>NZ_CP012390.1|WP_053962430.1|1673740_1674313_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSPAGKGGRLVGTLVRAAKNILSNPSTRRIVTRATQEAIRSFSGNTHDRQISRGGGRPTTRHAKSARSVARHLVYSPDLDGKADPGEIVWTWVEFEENASEGKDRPVLVVGRDRDTLLGLMLSSQSHRREDSNWEYLGRGSWDSQHRESYVRLDRVLEVPEAGIRREGAILDKERFEQVARRLRGEYGWS
>NZ_CP012390.1|WP_053962429.1|1673290_1673551_-|30S-ribosomal-protein-S20
MANIKSQKKRIRTNERARLRNQAIKSALRTDIRAFREAAEAGDKEKATEALRVASRSLDKAVSKGVIHKNQAANKKSAMAQQTNAL
>NZ_CP012390.1|WP_053962428.1|1672183_1673146_+|DNA-polymerase-III-subunit-delta
MNPLQLILGDEEFLIDRAIASIIRGVRAGMQSNPEELPVTKLRAGDVTPSEIVELLSPSLFAEDRVVVLEAAGEAGKEAAATIEQAVHEPAPGIVLVVVHSGGGRAKNLVTVLKKAGAEVTECPKITKVSEREAFVINEFRNLGVRPSSDAVHALLDAIGGDLRELASAVTQLVADTGGRVDSAAVRRYYAGVAGVTGFQVADDTLAGNTAAALTALRWALVGGLHPVPIADALGDSLLGMARLSAIGRVDPYSSAKTLGMPPWKIKKIQQQLRGWDAARLAQAMQIATELNGAVKGQSADAEYALEKAVREISQLAGRR
>NZ_CP012390.1|WP_158408654.1|1670013_1672179_+|ComEC/Rec2-family-competence-protein
MPPFSRNDTHLPHRHGDRVHDIRLVVPALCLWATALAGAEGGIHILGGIVASASVGAVIVWRVRRRRLESPLASLILAALLAVVLGGAAVLPHLFLTELGRRELYSAPTTASGLSAPFAARTPVAARTPVAAHAPSVTASAPRLLGSPTAASSRVVIGRITSRPLHNVTGTRFTLRTAHGEMIIHARAAQFQKLVLGQRVTLVVKPLRPPDHHLSLGEWRAIYLRSARAPQGMWAFSALVARQWEEALTLADTAGLTTSLHALARGMTIGDTSGLTPDQQRCYRASGLTHLTAVSGANVSYVLLLAGVTLHHASPRRRVIVHSLLLVLFAALIGPEPAVLRATISGAVGVLALWEGGRSAAFPALGAGILSLIIVSPLFAVSPGFLLSVAATAALIWAAPRLAEQLTQLGLPLVVGEVLAVAAVAASSTLPLSLYLFGTASVLGVLANTVVAPVVPLITAVGLVGVATSLFFPPVGAVVLMVLLPALWWVEKVGRALGGPGWAQLALPEKLSPGLVPTLVPSLLATAVLAAAVLACHTRRGRGVVVALVIVAGVVTGGHAAGSYRHMTTCQRQPDALTLVSSASDFTASPFTATGATHTVGVKHQGSHHQSQRSVILLEGRLTAAALPHIDELAASMQHPVLVHLSTAASHATITRGSRPSAHRSGPTPFSVSPRVSPTESSVASSRVSFTPGGTPVVELAAGETVTITATNQICAIGMAR
>NZ_CP012390.1|WP_053962437.1|1684229_1684985_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MSLPVFRIDPADMNAEPGAILTLEGAEGRHAVTVKRLRVGEKFMIGDGAGTLAVCRVTDIDGKDALHATVDGVKNVSRQKPAVTIVQGIPKGDAADLAVDLATEAGVDRIIPWQAERCIAQWSGSKKEKGRAKWQKTAIEAAKQSRRAWDPEVTPVAALDDIAKLVSETQKASGVVAILHESARVKFSSLPFNRAKSIVLIVGPEGGLTKEEITALETAGGQSVIMGPTVLRSAVAGAVALGAMGVLTERW
>NZ_CP012390.1|WP_063665785.1|1685002_1686049_+|PhoH-family-protein
MPFITRTFTLEGDTMPALLGAHDANLRELEKLLTSDIHVRGTELTLAGDPDDPTDLPLSQAVITSLLDTVEQGVILDVPMVRRTVSMLAGSGHDQPSEVFSTRVVNVRGRTIRAQTSGQKHYVEAIANHTIVFGIGPAGTGKTYLAMAMAVNALRSKDVNRIILTRPAVEAGENLGFLPGTLNDKIDPYLRPLYDALRDMMEPEQARKMMDTGVIEVAPLAYMRGRTLNNAFVILDEAQNTTAEQMKMFLTRLGAGSTMVITGDATQVDLPGGKTSGLRIARRVLEGTHPDIAFIDLTSEDVVRHSLVTAIVEAYGRYDEEQEERREQQSSQRKGGSRQGPSQRKHEN
>NZ_CP012390.1|WP_053962438.1|1686052_1686523_+|rRNA-maturation-RNase-YbeY
MSIEVANESGMDVDETILIDVATYVLQRMDVHPAAELAITLVDLDAIEQLHVQWLDLPGPTDVMSFPMDELTPGGRPDAVQPGPAMLGDIVICPQFAADQAKRAGHGAGHEMALLTVHGVLHLLGYDHATAAEEQEMFSLQNALLAEWYDQRDSRV
>NZ_CP012390.1|WP_053962439.1|1686544_1687897_+|HlyC/CorC-family-transporter
MSVLAILSLVFGLLLMVFAALCAAQDTALNNVSPARVVEIAHENELGSRKMLYVVERRDTYSALTVFLRTTSELVATILFATLFLDTVGTMDGRGAGTAWALVYTGIVSVLCSYVVVGVSARTLGLQNPYMVLRYTAVLLITVGWVFRPISRFLVRIGNALTPGKGFKEGPFSTDIELKEFVTLAQQRGVVEDDEREMIESVFQLGANNARSAMVPRTDMVWIESTKTANQAIKLAVKSGFSRIPVIADTVDDVVGIVYLKDLVAYTYSAVEGADSVTVGELMRPAWFIPDSKSLDDVLDEMRAKRNHIAVLIDEYGGVAGLITIEDILEEIVGEISDEYDASEVAPLEELGDNRWRASARLSIDDLAEAVGVEFNEELLDEVDTVGGLLAYELGRVPLPGAHIHTDTLNLVAEAGHDHRGRRRVTTVLVEKILPANDNTPDDENEDQND
>NZ_CP012390.1|WP_053962440.1|1687889_1688816_+|GTPase-Era
MTEYSVDQPNIPYRSGFVCFVGRPNTGKSTLTNAMVGQKIAITSNRPQTTRHTIRGIITTDGAQLIVVDTPGLHRPRTLLGERLNELVKDTFAGVDIIGLCIPADESIGPGDRWILDQVRTNVPRTPVIGIVTKIDKVSRDQIAAQLVAVSKLLGPDADVVPVSANSGEQVDTVVDVFTSLLPVGPQFYPEEELTDDDTEKFLSELIREAVLEDVREELPHSIACSIEEMYPDPDDEGRTVVHATIYVERESQKGIVIGKKGTRLRKVGQRARQSISQVLGTRVYLDLHVKVLKDWQTDPKQLGKLGF
>NZ_CP012390.1|WP_053962441.1|1688818_1689583_+|DNA-repair-protein-RecO
MPSYRDQGLVLRHYNLGEADRIVVLFTRGHGVVRCVAKGVRRSRSRFGARLEPFTLSDVQIYPGRNLSTITEAVTVETFNARIVADYGRYTAAAAILEATERLLGEEQPNQRLFDLTVGVLGALAEGQRAPQQMVDTYLLRAMAEAGWAPELEKCAVCGVEGSHQAFHPAAGGVVCAQHRPPGSATPMSGVLDYLRALRDARWERVDVIAGDRKLGQRVQEEAHRLVVSHLQWHTERKITALDVAAEAERGQRR
>NZ_CP012390.1|WP_053962751.1|1689783_1690560_+|isoprenyl-transferase
MDACFEGHDFTSAPPAIPAEFLPRHIALVMDGNGRWAQQRGMTRTEGHRRGEAVLLEACRACLEAGVPWLSAYAFSTENWTRSYEEVRFLMSFSRDVLRWQRDELNEMGVRIHWAGRRPRLWPSVIKELEIAEELTRHNDKMHLVMCVNYGGRAEITDAANRLAMAVKEGVLDPRDISEKTLSSLMYVPEMPDVDLFFRPSGEKRTSNFLLWQSAYAEMVYQDVLFPDFDRSHLWAALDEYARRDRRFGGVKTPHSGE
>NZ_CP012390.1|WP_082345518.1|1690588_1690951_-|helix-turn-helix-transcriptional-regulator
MAEAPEEHSSGLVDKDLAELPPQKVMEAAGTLLQSLTAPARIAIIVQLQHRPCCVHELVAALDIPQPAVSQHLRVLKNAGVVKSTRRGREHEYSLVDEHLTGIVNDALCHAEEILHHRFL
>NZ_CP012390.1|WP_172621866.1|1691135_1692527_+|glycine--tRNA-ligase
MAVAKNNLVESVANLCKRRGIVYPCGEIYGGTRSAWDYGPLGVELKDNIKRQWWNSMVRSRDNVVGLDSSIILPRQVWEASGHVEVFTDPLVESLYTHKRYRADHLLEAYEEKHGHAPANGLADVPDPETGQPGNWTEPKAFSGLMKTYLGPVDDKEGLHYLRPETAQGIFVNYKNVMTTSRMKVPFGIGNIGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGEDEEWHQYWIDERWKWYTDLGVREENLRLYEHPKEKLSHYSKRTVDIEYAFHFTGSTWGELEGVANRTDYDLTVHSKHSGEDLSFFEQATGERFIPYVIEPAAGLTRSLMCFLVDAYEEEEIPKANGKIDKRTVLHLDPRLAPVKAAVLPLSRNEELSPVARCLANQLRQRWNVDFDDAQGIGKRYRRQDEIGTPFCVTVDFDTKDDQAVTIRERDTMSQERVSLDNVENYLAERLRGC
>NZ_CP012390.1|WP_063665786.1|1692638_1693511_+|trimeric-intracellular-cation-channel-family-protein
MDGVLLNQELVFRVIDLTGVVGAGCLGGTVARRHKFDLVGFLILGISTALGGGILRDLMLNLTPIALTDYAYLVAAVCGVFISMVLRIDGRKFWVNLFSLVDAMTIGSWAATGASKTLAAGLGVGPALVLGVITAVGGGVTRDILVGRTPEVFGGNTLYATPALAGAGVVTMVHGIGYPGVGMIAGTITGIALCLPAQLFGWSLPVIPDWSLDSAAAEMLRKVKGDKSRRAKSHLKGLQMMEEQVHQAQMQAAEDAATSEPGDGFPADTEPPGEGPEEGTPPSPFFDKTV

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP012390_3	3.1|1007669|25|NZ_CP012390|PILER-CR	1007669-1007693	25	NZ_CP012390.1	1423270-1423294	0	1.0
NZ_CP012390_3	3.3|1007666|28|NZ_CP012390|CRISPRCasFinder,CRT	1007666-1007693	28	NZ_CP012390.1	1423267-1423294	0	1.0
NZ_CP012390_2	2.1|842715|60|NZ_CP012390|CRISPRCasFinder	842715-842774	60	NZ_CP012390.1	1023073-1023132	1	0.983
NZ_CP012390_2	2.2|842802|42|NZ_CP012390|CRISPRCasFinder	842802-842843	42	NZ_CP012390.1	1023004-1023045	1	0.976
NZ_CP012390_2	2.3|842871|51|NZ_CP012390|CRISPRCasFinder	842871-842921	51	NZ_CP012390.1	1022932-1022982	1	0.98

1. spacer 3.1|1007669|25|NZ_CP012390|PILER-CR matches to position: 1423270-1423294, mismatch: 0, identity: 1.0

gacgggtgaacacctccccgaggtc	CRISPR spacer
gacgggtgaacacctccccgaggtc	Protospacer
*************************

2. spacer 3.3|1007666|28|NZ_CP012390|CRISPRCasFinder,CRT matches to position: 1423267-1423294, mismatch: 0, identity: 1.0

ggtgacgggtgaacacctccccgaggtc	CRISPR spacer
ggtgacgggtgaacacctccccgaggtc	Protospacer
****************************

3. spacer 2.1|842715|60|NZ_CP012390|CRISPRCasFinder matches to position: 1023073-1023132, mismatch: 1, identity: 0.983

gttgggggaggatgcgttcggtgttgtgtgctgagcggcgggggcggcggggtgtggtct	CRISPR spacer
gttgggggaggatgcgttcggtgttgtgtgctgagcggcgggtgcggcggggtgtggtct	Protospacer
****************************************** *****************

4. spacer 2.2|842802|42|NZ_CP012390|CRISPRCasFinder matches to position: 1023004-1023045, mismatch: 1, identity: 0.976

ttccgggggttccggggatgccggatgtgccggggcggcctg	CRISPR spacer
ttccgggggttccggggaggccggatgtgccggggcggcctg	Protospacer
****************** ***********************

5. spacer 2.3|842871|51|NZ_CP012390|CRISPRCasFinder matches to position: 1022932-1022982, mismatch: 1, identity: 0.98

tgccggatttagctggggagcctgaaccggcaggggctttcgtgctggaac	CRISPR spacer
tgccggatttagctggggagcctgaaccggcaggggctttcgtgccggaac	Protospacer
*********************************************.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012390_3	3.1|1007669|25|NZ_CP012390|PILER-CR	1007669-1007693	25	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	196344-196368	5	0.8
NZ_CP012390_3	3.3|1007666|28|NZ_CP012390|CRISPRCasFinder,CRT	1007666-1007693	28	NC_048782	Rhodococcus phage Sleepyhead, complete genome	1087-1114	5	0.821
NZ_CP012390_3	3.13|1008306|28|NZ_CP012390|CRISPRCasFinder,CRT	1008306-1008333	28	NZ_CP053910	Hymenobacter sp. BRD128 plasmid unnamed2, complete sequence	12546-12573	5	0.821
NZ_CP012390_3	3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008946-1008973	28	NZ_CP045721	Pantoea eucalypti strain LMG 24197 plasmid unnamed1, complete sequence	17718-17745	5	0.821
NZ_CP012390_3	3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008946-1008973	28	NZ_CP022517	Pantoea vagans strain FBS135 plasmid pPant1, complete sequence	386922-386949	5	0.821
NZ_CP012390_3	3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008946-1008973	28	NZ_CP010024	Paraburkholderia fungorum strain ATCC BAA-463 plasmid pBIL, complete sequence	355471-355498	5	0.821
NZ_CP012390_3	3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008946-1008973	28	NC_012527	Deinococcus deserti VCD115 plasmid 1, complete sequence	198063-198090	5	0.821
NZ_CP012390_6	6.1|1683521|26|NZ_CP012390|CRISPRCasFinder	1683521-1683546	26	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	313828-313853	5	0.808
NZ_CP012390_3	3.6|1007858|28|NZ_CP012390|CRISPRCasFinder,CRT	1007858-1007885	28	NZ_CP045062	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p3, complete sequence	21833-21860	6	0.786
NZ_CP012390_3	3.6|1007858|28|NZ_CP012390|CRISPRCasFinder,CRT	1007858-1007885	28	NZ_CP045055	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p3, complete sequence	21834-21861	6	0.786
NZ_CP012390_3	3.7|1007922|28|NZ_CP012390|CRISPRCasFinder,CRT	1007922-1007949	28	NZ_CP014600	Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence	210483-210510	6	0.786
NZ_CP012390_3	3.13|1008306|28|NZ_CP012390|CRISPRCasFinder,CRT	1008306-1008333	28	NC_048796	Panteoa phage Kyle, complete genome	27053-27080	6	0.786
NZ_CP012390_3	3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008818-1008845	28	NZ_CP035514	Haematobacter massiliensis strain OT1 plasmid pOT1-4, complete sequence	142516-142543	6	0.786
NZ_CP012390_3	3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008818-1008845	28	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	599754-599781	6	0.786
NZ_CP012390_3	3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008946-1008973	28	CP003956	Rhodococcus opacus PD630 plasmid 7, complete sequence	19170-19197	6	0.786
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP015738	Shinella sp. HZN7 plasmid pShin-02, complete sequence	71595-71625	6	0.806
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP035512	Haematobacter massiliensis strain OT1 plasmid pOT1-2, complete sequence	342150-342180	6	0.806
NZ_CP012390_3	3.2|1007733|28|NZ_CP012390|PILER-CR	1007733-1007760	28	MN150686	Bacillus phage BC-T25, complete genome	8908-8935	7	0.75
NZ_CP012390_3	3.4|1007730|28|NZ_CP012390|CRISPRCasFinder,CRT	1007730-1007757	28	MN150686	Bacillus phage BC-T25, complete genome	8908-8935	7	0.75
NZ_CP012390_3	3.12|1008242|28|NZ_CP012390|CRISPRCasFinder,CRT	1008242-1008269	28	MN693339	Marine virus AFVG_25M331, complete genome	30771-30798	7	0.75
NZ_CP012390_3	3.13|1008306|28|NZ_CP012390|CRISPRCasFinder,CRT	1008306-1008333	28	NZ_AP021860	Alteromonas sp. I4 plasmid pAltI4, complete sequence	17750-17777	7	0.75
NZ_CP012390_3	3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008818-1008845	28	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	674815-674842	7	0.75
NZ_CP012390_3	3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008946-1008973	28	MK448234	Klebsiella phage ST11-VIM1phi8.2, complete genome	27657-27684	7	0.75
NZ_CP012390_3	3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008946-1008973	28	MK714353	Klebsiella phage ST13-OXA48phi12.5, complete genome	14605-14632	7	0.75
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	85212-85242	7	0.774
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	718913-718943	7	0.774
NZ_CP012390_3	3.2|1007733|28|NZ_CP012390|PILER-CR	1007733-1007760	28	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	28735-28762	8	0.714
NZ_CP012390_3	3.2|1007733|28|NZ_CP012390|PILER-CR	1007733-1007760	28	KY794642	Staphylococcus phage vB_Sau_Clo6, complete genome	127868-127895	8	0.714
NZ_CP012390_3	3.4|1007730|28|NZ_CP012390|CRISPRCasFinder,CRT	1007730-1007757	28	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	28735-28762	8	0.714
NZ_CP012390_3	3.4|1007730|28|NZ_CP012390|CRISPRCasFinder,CRT	1007730-1007757	28	KY794642	Staphylococcus phage vB_Sau_Clo6, complete genome	127868-127895	8	0.714
NZ_CP012390_3	3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008818-1008845	28	NZ_AF135182	Serratia entomophila strain A1MO2 plasmid pADAP, complete sequence	150814-150841	8	0.714
NZ_CP012390_3	3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1008818-1008845	28	NC_002523	Serratia entomophila plasmid pADAP, complete sequence	150376-150403	8	0.714
NZ_CP012390_3	3.24|1009010|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1009010-1009037	28	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	28735-28762	8	0.714
NZ_CP012390_3	3.24|1009010|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR	1009010-1009037	28	KY794642	Staphylococcus phage vB_Sau_Clo6, complete genome	127868-127895	8	0.714
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NC_014718	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence	291763-291793	8	0.742
NZ_CP012390_5	5.4|1065078|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065078-1065110	33	NZ_CP025547	Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence	276605-276637	8	0.758
NZ_CP012390_5	5.8|1065323|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065323-1065355	33	MH067975	Arthrobacter sp. strain ANT_H58 plasmid pA58H2, complete sequence	31835-31867	8	0.758
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	1449263-1449293	9	0.71
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	1038731-1038761	9	0.71
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	1608552-1608582	9	0.71
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	1593190-1593220	9	0.71
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	1536759-1536789	9	0.71
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP015234	Epibacterium mobile F1926 plasmid unnamed4, complete sequence	23486-23516	9	0.71
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	147739-147769	9	0.71
NZ_CP012390_4	4.1|1020265|31|NZ_CP012390|CRISPRCasFinder	1020265-1020295	31	NZ_AP014802	Rhodovulum sulfidophilum plasmid Plasmid2 DNA, complete genome, strain: DSM 2351	54877-54907	9	0.71
NZ_CP012390_5	5.8|1065323|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065323-1065355	33	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	193691-193723	9	0.727
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP032350	Azospirillum brasilense strain MTCC4039 plasmid p5, complete sequence	125665-125697	9	0.727
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	564089-564121	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	553704-553736	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	449653-449685	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	519004-519036	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	449653-449685	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	456893-456925	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	456883-456915	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	449665-449697	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	449685-449717	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	449652-449684	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	564132-564164	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	564132-564164	10	0.697
NZ_CP012390_5	5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT	1065872-1065904	33	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	564123-564155	10	0.697

1. spacer 3.1|1007669|25|NZ_CP012390|PILER-CR matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 5, identity: 0.8

gacgggtgaacacctccccgaggtc	CRISPR spacer
tgggggtgaacacctccccgagcta	Protospacer
 . ******************* * 

2. spacer 3.3|1007666|28|NZ_CP012390|CRISPRCasFinder,CRT matches to NC_048782 (Rhodococcus phage Sleepyhead, complete genome) position: , mismatch: 5, identity: 0.821

ggtgacgggtgaacacctccccgaggtc	CRISPR spacer
ggtgacgggtgaagacctcgccgttgtt	Protospacer
************* ***** ***  **.

3. spacer 3.13|1008306|28|NZ_CP012390|CRISPRCasFinder,CRT matches to NZ_CP053910 (Hymenobacter sp. BRD128 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.821

ggctgatccgctgggcattgacgacttc	CRISPR spacer
cgctgataagctgggcattgacgacgtg	Protospacer
 ******  **************** * 

4. spacer 3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045721 (Pantoea eucalypti strain LMG 24197 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.821

cgccgcactcatgaccgtactggtcagc	CRISPR spacer
gtcagcacgcatgaccggactggtcagc	Protospacer
  * **** ******** **********

5. spacer 3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022517 (Pantoea vagans strain FBS135 plasmid pPant1, complete sequence) position: , mismatch: 5, identity: 0.821

cgccgcactcatgaccgtactggtcagc	CRISPR spacer
gtcagcacgcatgaccggactggtcagc	Protospacer
  * **** ******** **********

6. spacer 3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010024 (Paraburkholderia fungorum strain ATCC BAA-463 plasmid pBIL, complete sequence) position: , mismatch: 5, identity: 0.821

cgccgcactcatgaccgtactggtcagc	CRISPR spacer
ggccgcactcattaccgcactggtgatc	Protospacer
 *********** ****.****** * *

7. spacer 3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NC_012527 (Deinococcus deserti VCD115 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.821

cgccgcactcatgaccgtactggtcagc	CRISPR spacer
ccgcacactcatgaccgtaccgctcagc	Protospacer
*  *.***************.* *****

8. spacer 6.1|1683521|26|NZ_CP012390|CRISPRCasFinder matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 5, identity: 0.808

atcagaatccggagcccagcccgaaa	CRISPR spacer
catagaatccggcgccgagcccgaaa	Protospacer
  .********* *** *********

9. spacer 3.6|1007858|28|NZ_CP012390|CRISPRCasFinder,CRT matches to NZ_CP045062 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p3, complete sequence) position: , mismatch: 6, identity: 0.786

gtgacctcccggaagtggcggatcatca	CRISPR spacer
gtgaactcccggaagtggaggatgcgga	Protospacer
**** ************* ****    *

10. spacer 3.6|1007858|28|NZ_CP012390|CRISPRCasFinder,CRT matches to NZ_CP045055 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p3, complete sequence) position: , mismatch: 6, identity: 0.786

gtgacctcccggaagtggcggatcatca	CRISPR spacer
gtgaactcccggaagtggaggatgcgga	Protospacer
**** ************* ****    *

11. spacer 3.7|1007922|28|NZ_CP012390|CRISPRCasFinder,CRT matches to NZ_CP014600 (Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.786

cgcccgtgattgttccgctcgaccccac	CRISPR spacer
agcccgtgatagtgccgctcgacctcct	Protospacer
 ********* ** **********.* .

12. spacer 3.13|1008306|28|NZ_CP012390|CRISPRCasFinder,CRT matches to NC_048796 (Panteoa phage Kyle, complete genome) position: , mismatch: 6, identity: 0.786

ggctgatccgctgggcattgacgacttc	CRISPR spacer
cgctgacccgctggccattgacgacact	Protospacer
 *****.******* ********** ..

13. spacer 3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035514 (Haematobacter massiliensis strain OT1 plasmid pOT1-4, complete sequence) position: , mismatch: 6, identity: 0.786

accatcgccggcatgatcaacggagcag	CRISPR spacer
tccatcggcggcatgatcatcggagtgt	Protospacer
 ****** *********** *****.. 

14. spacer 3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.786

accatcgccggcatgatcaacggagcag	CRISPR spacer
accatcgccggcaagatcaccggcccgt	Protospacer
************* ***** ***  *. 

15. spacer 3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to CP003956 (Rhodococcus opacus PD630 plasmid 7, complete sequence) position: , mismatch: 6, identity: 0.786

cgccgcactcatgaccgtactggtcagc	CRISPR spacer
cgccgcactcctggccgtactggttgcg	Protospacer
********** **.**********..  

16. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP015738 (Shinella sp. HZN7 plasmid pShin-02, complete sequence) position: , mismatch: 6, identity: 0.806

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
cagccaagcatcgcccgcgccgcgcggagct	Protospacer
**************** ****** .**  * 

17. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP035512 (Haematobacter massiliensis strain OT1 plasmid pOT1-2, complete sequence) position: , mismatch: 6, identity: 0.806

--cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
agcagc--agcatcgcccccgccgccagccctc	Protospacer
  ****  ****************** * **. 

18. spacer 3.2|1007733|28|NZ_CP012390|PILER-CR matches to MN150686 (Bacillus phage BC-T25, complete genome) position: , mismatch: 7, identity: 0.75

tggggatgagtataagcaagtagcatcg	CRISPR spacer
gcggtatgagtataagaaagtagcaatc	Protospacer
  ** *********** ******** . 

19. spacer 3.4|1007730|28|NZ_CP012390|CRISPRCasFinder,CRT matches to MN150686 (Bacillus phage BC-T25, complete genome) position: , mismatch: 7, identity: 0.75

tggggatgagtataagcaagtagcatcg	CRISPR spacer
gcggtatgagtataagaaagtagcaatc	Protospacer
  ** *********** ******** . 

20. spacer 3.12|1008242|28|NZ_CP012390|CRISPRCasFinder,CRT matches to MN693339 (Marine virus AFVG_25M331, complete genome) position: , mismatch: 7, identity: 0.75

tacgtcggatattgtctttgaagtaggt	CRISPR spacer
ggtgccggatatcgtctttgaagtagcg	Protospacer
 ..*.*******.*************  

21. spacer 3.13|1008306|28|NZ_CP012390|CRISPRCasFinder,CRT matches to NZ_AP021860 (Alteromonas sp. I4 plasmid pAltI4, complete sequence) position: , mismatch: 7, identity: 0.75

ggctgatccgctgggcattgacgacttc	CRISPR spacer
ggctgatgcgctgggcattgatgttaca	Protospacer
******* *************.* . . 

22. spacer 3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 7, identity: 0.75

accatcgccggcatgatcaacggagcag	CRISPR spacer
cccatcgccggcatgatcgacgtggtga	Protospacer
 *****************.*** .*...

23. spacer 3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to MK448234 (Klebsiella phage ST11-VIM1phi8.2, complete genome) position: , mismatch: 7, identity: 0.75

cgccgcactcatgaccgtactggtcagc	CRISPR spacer
gaaagacctcattaccgtactggtcagc	Protospacer
 .  *  ***** ***************

24. spacer 3.23|1008946|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to MK714353 (Klebsiella phage ST13-OXA48phi12.5, complete genome) position: , mismatch: 7, identity: 0.75

cgccgcactcatgaccgtactggtcagc	CRISPR spacer
gaaagacctcatcaccgtactggtcagc	Protospacer
 .  *  ***** ***************

25. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 7, identity: 0.774

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
cagccaatcatcgcccgcgccgccggtcagc	Protospacer
******* ******** ******* * *   

26. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 7, identity: 0.774

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
ctgagaagcatcgcctccgccgccttgcgcc	Protospacer
* *  **********.********* ** * 

27. spacer 3.2|1007733|28|NZ_CP012390|PILER-CR matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.714

tggggatgagtataagcaagtagcatcg	CRISPR spacer
attagatgagtataaggaagtagcagat	Protospacer
   .************ ********   

28. spacer 3.2|1007733|28|NZ_CP012390|PILER-CR matches to KY794642 (Staphylococcus phage vB_Sau_Clo6, complete genome) position: , mismatch: 8, identity: 0.714

tggggatgagtataagcaagtagcatcg	CRISPR spacer
attagatgagtataaggaagtagcagat	Protospacer
   .************ ********   

29. spacer 3.4|1007730|28|NZ_CP012390|CRISPRCasFinder,CRT matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.714

tggggatgagtataagcaagtagcatcg	CRISPR spacer
attagatgagtataaggaagtagcagat	Protospacer
   .************ ********   

30. spacer 3.4|1007730|28|NZ_CP012390|CRISPRCasFinder,CRT matches to KY794642 (Staphylococcus phage vB_Sau_Clo6, complete genome) position: , mismatch: 8, identity: 0.714

tggggatgagtataagcaagtagcatcg	CRISPR spacer
attagatgagtataaggaagtagcagat	Protospacer
   .************ ********   

31. spacer 3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AF135182 (Serratia entomophila strain A1MO2 plasmid pADAP, complete sequence) position: , mismatch: 8, identity: 0.714

accatcgccggcatgatcaacggagcag	CRISPR spacer
gacatcgccggcatgatcaaagggtggc	Protospacer
. ****************** **.  . 

32. spacer 3.21|1008818|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to NC_002523 (Serratia entomophila plasmid pADAP, complete sequence) position: , mismatch: 8, identity: 0.714

accatcgccggcatgatcaacggagcag	CRISPR spacer
gacatcgccggcatgatcaaagggtggc	Protospacer
. ****************** **.  . 

33. spacer 3.24|1009010|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.714

tggcgatgagtataagcaagtagcatcg	CRISPR spacer
attagatgagtataaggaagtagcagat	Protospacer
    ************ ********   

34. spacer 3.24|1009010|28|NZ_CP012390|CRISPRCasFinder,CRT,PILER-CR matches to KY794642 (Staphylococcus phage vB_Sau_Clo6, complete genome) position: , mismatch: 8, identity: 0.714

tggcgatgagtataagcaagtagcatcg	CRISPR spacer
attagatgagtataaggaagtagcagat	Protospacer
    ************ ********   

35. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NC_014718 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence) position: , mismatch: 8, identity: 0.742

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
tggcgggccatcgctcccgccgcctgaccca	Protospacer
..** .. ******.***********.****

36. spacer 5.4|1065078|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025547 (Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

taccgctcggtggtgaaagtcgcagacgacggc	CRISPR spacer
cgcgacgcgctggtgaaagtcgcagtcgacgac	Protospacer
..* .* ** *************** *****.*

37. spacer 5.8|1065323|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to MH067975 (Arthrobacter sp. strain ANT_H58 plasmid pA58H2, complete sequence) position: , mismatch: 8, identity: 0.758

agatctgtttccgtggccaccgacccagaaaca	CRISPR spacer
tttttggcttcagtggccaccgacccataaaca	Protospacer
   *. *.*** *************** *****

38. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.71

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
atcgcaagcatcgcccccgccgcgtgtggaa	Protospacer
    ******************* **    *

39. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.71

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
atcgcaagcatcgcccccgccgcgtgtggaa	Protospacer
    ******************* **    *

40. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 9, identity: 0.71

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
atcgcaagcatcgcccccgccgcgtgtggaa	Protospacer
    ******************* **    *

41. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.71

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
atcgcaagcatcgcccccgccgcgtgtggaa	Protospacer
    ******************* **    *

42. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.71

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
atcgcaagcatcgcccccgccgcgtgtggaa	Protospacer
    ******************* **    *

43. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP015234 (Epibacterium mobile F1926 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.71

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
ctctgcgccatcgcccgcgccgcccggccca	Protospacer
*  .  . ******** *******.******

44. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 9, identity: 0.71

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
cccgacgccatcgcccgcaccgcctggccca	Protospacer
*     . ******** *.************

45. spacer 4.1|1020265|31|NZ_CP012390|CRISPRCasFinder matches to NZ_AP014802 (Rhodovulum sulfidophilum plasmid Plasmid2 DNA, complete genome, strain: DSM 2351) position: , mismatch: 9, identity: 0.71

cagccaagcatcgcccccgccgcctggccca	CRISPR spacer
aggaacagcatcgcccccgccgccagcccgc	Protospacer
 .*   ****************** * **  

46. spacer 5.8|1065323|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 9, identity: 0.727

agatctgtttccgtggccaccgacccagaaaca	CRISPR spacer
cgccgcccttccgtggccaccgcccgagaaaca	Protospacer
 * . . .************** ** *******

47. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032350 (Azospirillum brasilense strain MTCC4039 plasmid p5, complete sequence) position: , mismatch: 9, identity: 0.727

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
gcgcacttggtcgctggtgccgccgccgcggtg	Protospacer
 . .** .***.***************** ** 

48. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

49. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

50. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

51. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

52. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

53. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

54. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

55. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

56. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

57. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

58. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

59. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

60. spacer 5.17|1065872|33|NZ_CP012390|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.697

ctctacacggttgctggtgccgccgccgccgtc	CRISPR spacer
ccgctggcggtcgatggtgccgccgccgccgcg	Protospacer
*. .  .****.* *****************. 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	65878 : 73179	7	Staphylococcus_phage(66.67%)	NA	NA
DBSCAN-SWA_2	99567 : 109995	7	Klosneuvirus(33.33%)	tRNA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP012390|65878:73179|DBSCAN-SWA
CCTACTCACGGCCCAAGTCGCGATGCACTGCCGTTACATTAGCGTCTGAAATAGCTTCTCCAAGGCGACGCGCCAGCTCCATGGTAGTCGCAACAGAGCGATGCTTCCCGCCAGTACACCCCACACCCAACAGCACATAAGCCTTGCCCTCAGCACGATATCCAGGCGTCGCCAAGGTAATCATGTGGGCAAAGCTTTCAATAAACCCCTCCGCGACATCATTATTGAGCACATACTCAGCCACATCCGCATCCATTCCAGAGTGCGGCCGCAACGCTGGTACCCAGTACGGGTTAGGAAGAAAACGCATATCAACGACGAAATCAGCGTCAAGTGGTATGCCGTATTTAAACCCGAAGGACTCCACAATAATGTCAAGTCCTTTCTCCCCCGAGGCACGAAACTCTGACAACCGTTCACGCAACTTTGTGGAGGTCAAACGTGAGGTATCCACGACGAGATCCGCATGGTTCTTCAAGTCCGCCAGCAGCTCACGCTCGTCTTTAATACCCTCCTCCAAAGGGCGTTTATCCTGCAAAGGGTGGGTCTTTCGCAATTGGTTATAGCGTCGAATAAGCACCTCATCGGACGCATCGAGGAAGAGCACACGGGGCGACCAACCACGCGAGCGCAACTCATGGACAACGAAGTCGAGGGAGCCAGAAAAACTCTGCGAGCGAACGTCAGTCACAATGGCTAAACGCCGGATCTCTCGCTTAGAGTTCTGCGTAATTTCAGCGGTACGAACAATGAGCTCCATTGGCAAATTATCGACGACATACCAGCCGAATTCCTCCAGCAGTCGGGCAGCGGTTCCACGTCCCGCACCGGACATGCCAGAAATAAGAACGATCTCTAAGGGGTCAGTAGACACAGTGCGAGCCTCACTCTCTAGTGATCCACAATGACAGCACCGAGAGCGGTGCCGACCTCACCTCATAGTGTGCCAGATTTAACCGTGCAGAGCCGCAAAAACCTTCTTAGCCCGCTGTGGACCGAAACCAGGGACTGCTGCTATCTCCTCAGCGTTGGCTTCCCGCAGCTTTTTCATCGTTCCGAAATGGTTCATCAGCGCTTGGTGAAGAGCCGGGCCAACCCCTTCAATCCTTTCCAGTTCCGACGCGACCATGTCCTTCGAGCGACGCTTCCGGTGGAATCCGATAGCCGTACGGTGGGATTCATCGCGTACTCGCTGTAACAAATACAGCGCTTCAGATTCACGCGGGAGGATAAGAGGATGCTCTTCCTCCGGTACCCACACTTCTTCAAGGCGCTTTGCTAGCCCGACAACGGGCAGGTCCGTAATACCAAGCTCGTTCAGTACCCCAGCAGCCGCAGCGACCTGCGGAGCACCACCGTCTACGACAAAAAGCTGCGGTGGATAGACGCTGCGCCGTGCTGGTACGTCCGCAATACTCCCCGCGCTATCCGGAACAGCGCGCGCATCCTCACGATAATGCTGAAAACGCCGACGCGTTACCTCTGCGATGGAGCCCACATCATTCGACTGCCCATCACCTGCCGCCTCTTTAATGAGGTAGGTGCGGTAATCAGACTTTCGCGGTAACCCGTCCTCAAACACCACCAAGGACGCCACAACATTAGTGCCCTGGATATGGCTAATATCGGTACATTCAATACGCAATGGTGGCTGTGGAAGACCTAGGTAGGTCTGGAGTTCTTCGAGCGCCAACGAGCGAGACGTCAGATCGGACGCACGTTTCAACTTATGCTGGCGCAGCGCTTCCGCAGCATTCTCCGTCACCGTCTCCATAACGCGAACAAGGTCTCCCCGCTGTGGTTGTCGAATCTCCACTCGACTATTGCGGATAGTAGACAATTGCTCCGTCAGTTCTTCCGCGTGAGGCGGCAGCACCGGAACAAGGATCAGACGCGGAATGTCTCCGGGATGCGTGTTGTAGAACTGTGGGAGAAAACTCTCCACCACATAGGGCAGGGCAGGATCGGGTACATTATCCTCCCAGTCCCCCAGATCCGACTCCCCTGTTTTCGATACCACCCAACCCTGTTGGCCGACGATACACCCATGCCGAAAACGGAAAAGCTGAACAGATGCTTCAATCTCATCAGTCGCCACACCAATAACATCCGCATCTAACGTTTCCTGCAGCACCACAGCCTGCTTCTCCAACACCGCTTGTAAAGCTGCAATGTGGTCACGCAGACGCGCTGCCTTTTCAAAATCGAGGGCAGCAGCAGCCTCATTCATTTCTGCGGTCAAACTGCGAACAATTTCTTTGTCTTGGCCGGTGAGGAAACGCTCCAACTGCACAATAAGTGCGTTATAGTCGGCGAGCTCAACCTGTTCCACACACGGTGCACAACACTTGCCGATATAGCCCAGTAGGCATGGTCGTCCTAAAGCAGTATGTCGGTTAAACACTCCATTTGTGCAGGTACGAACAGGAAAAACCTTCGTGAGTTGGTCCAGGGTATCACGCAATGCCCCGACTTTTGGGTAAGGGCCGAAGTAGCGCACGTTCTTCCGTCTCGCCCCACGATAGACCCAGACACGTGGATAGGTATCCGCCGAAGAGATAGCGAGAAGTGGATAGGACTTATCATCTCGGAATTGAATATTGAAGCGGGGCGAAAAATGCTGAATCCATGTCCACTCGAGCTGCAACGCCTCACCCTCATTGGCCACAACGGTCCAATCAACACTAGCCGCTTGGCTCAGCATTCGACGCGAGAGTGGTCGAATGTTCTCCGCCGAGACAAAGTAGGAGTTCAGCCGATTGCGGAGATTCTTTGCTTTTCCCACATAAATGACACGCCCATAACTATCACGAAATCGGTAGACACCAGGTTTGGTGGGAATCGTTCCAGGGGCAGGGCGAAAATCTGCGGGAGATCCCATGCCCACTATCCCACCTGGCGAAGGCGCTTCAGCTCGCTTGCCACTTCCAACGCTGCGAAGGTAGCTTCGCCACCCTTATCTTCGACAGAATCTGCAAAACCAGCACGGTCATGGGCCTGTGCCACGGTATTCACGGTCAACACAGCATTCCCTACCGGGGTAGCTTCATCCAACGCTACACGCGTCAACCCATCGGTGACAGATTGGCACACGTAATCAAAATGGGCAGTGTCACCACGAATGACAACGCCAATCGCCACCACCGCATCGTGGGTGCGCGCGAACTGCTGTGCTACTACTGGCAGTTCAATTGATCCAGCGACACGAGCGACGTCGACGGTAGCACCAGCCTGTTCCGCCACCTCCCGAGCTCGAGTGAGCATCTGATCACACAGGTCACGATTCCACTGTGCAGCGACGATACCGACACGCATGCCAGCGGCGTCAAGAGTGGCGATACCGGGGCGGCCTGCTTCAGCCATGTCTGCTCCTTGAATACACAAGTGGGGTCGTGGATACTCTCCCATCCTACCCAGCAGAACCGAGGGAACGACGAATCACCAGGGCAAGGAAGCCGTTATCCAAAACACACCTTAACGGGAATGTTGGTGATGGGAGCACCCACAGTCGCCATCAGCACAGTGATGATGGGCGTCCTCGTTAACAGCTGTGCGAGTGTGGTCATGGTCGATCCAAGCGGAGCTTTGCACGTCACTCGTTGCGCTGCCAACAACCGCGTCGAGATCTTCAAGAGCGTGCCCCATACGATCGCGTTTAGTACGCAAGTAAGTGAGGTTCTCGGGAGTGACATCTAGTGGCAAATGAGCGCGTCCGGTGATCTCCACTCCATAACCTTCTAGGCCCTCTCGCTTGTCGGGATTGTTCGTCAGTAAACGCATAGAGCGCACACCGAGGTCGTAAAGAATCTGGGCTGCCGACGCGTATTCACGCGCATCTGCAGGCAATCCCAACTTGAGATTGGCGTCAACAGTATCTTCGCCCTCATCCTGCAAATGGTATGCACGAAGTTTGTTCAAAAGGCCAATTCCGCGACCTTCATGACCGCGGAGATAGAGAACAATACCGCGGCCCTCTGCATCAATCATGTCGAGGGAACGGTGAAGTTGGGGTCCGCAGTCGCAACGTCGAGATCCGAAAACATCGCCGGTGAGGCATTCTGAGTGTACCCGCACCAGCACGTCTCGTCCGTCATCGGCAGCAACGTCGCCCTTGACAACGGCGACATGCTCCTGGCCATCAATCAAAGAACGGTATCCGACAATCCGAAAGTTCCCGTACTTCGTGGGAAGATTGGCATCAGTGACTCGCTCTACCAGCTTCTCGTGTTGGCGACGCCACTGGATGAGGTCCTTAATGGAAATCATCGCGATCTTATGGTGGTTGCACCACTCACGCAGCTCAACGGCCCGCGCCATGGTAGTGGGATCTTTCTCAGAGACGATCTCGCAAAGTGCACCTGCCGGGGAAAGGCCTGCTAAACGAGCAAGGTCGACAGAGGCTTCAGTGTGACCGGCCCGCACCAGTACCCCGCCGGAGACAGCGCGGAGCGGCAAAACGTGCCCTGGCCGGTTAAGGCTAGCAGGACCCGCCACAGGATCAGCCAAGGTACGAATAGTCCGAGCACGGTCAGCAGCAGAGATACCGGTGGTCGTTCCTTGTGCTGCATCTACAGTAATAGTGTAGGCGGTCTTTCGGGGGTCTTCACTGTGTGCCACCATCGCTGGCAAATGCAGACGATCGCACAGCTCACCATCCATTCCGACACAGATGTAGCCGGAGGTGTAGCGAATCATAAAAGCAAGGAGCTGTGGTGTCGCCTTTTCGGCAGCAAAAATCAGGTCCCCTTCGTTTTCACGATTCTCATCGTCGACGACGACAACTGGCTGGCCAATGCCGAAGTCGGCAATGGCCTGCTCAATACTGTCGAATTCGATCACAGGTGGTGCGCTCCTTGGAGTCTGGGGATGTCCTCATCGTACTTGTTACTGTACGGGATCATGAACCCGTCGCCACTCCGCCAAATCGGCGATGGAAATCATCGCGATCTTATGGCGGTTGCACCATTCACGCAGTTCTTCTCGCCGCGCCATCGTCGTCGGGTCTTTCTCGGAGACGATTTCACACAGTGCCGCTACCGGCTCATAGCCGGCGAGTCTAGCGAGATCAGATCCCGCCTCAGTGTGCCCCACTCGGTGGAAAACGCCGCCAGCTACAGCGCGAAGAGGCAGAACATGGCCAGGGCGATGGAAGTCACTTGCGACAGAGGCTGGATCACCGAGTTTCTTGATAGTGAGGGCTCGATCATGGGCAGAAATTCCGGTTGTGGTTCCTTCTGCAGCGTCCACGGACACGGTGTAAGCAGTGAGGCGACGATCTTCGCTCTTTTCCCACATAATGGGAAGAGCTAAACGATCGCAGATGTTCGCATCCATACCGACGCAGATATATCCCGAGGTGTAGCGGATCATAAAGGCAAGCAGCTCGGGAGTAGCTGCAGCGGCAGGGAAAATCAGGTCCCCTTCGTTTTCACGGTTATCATCGTCGACAACAACAACGGGACGACCTTGTCGGAATTCTTCAATAGCAGTTTCGATGCTCTCGAAAAGGCTCACGATTTCACTCTCGTTCTGTGGTGGTGACGTGTCTAGTATGGCCTATACAGGGGCGGACTAGAGAACTGGGATGGTGACAGATCTCTTACTTATAGGGAGTAAGGAGATGATCGACATATTTGGCGATCGCGTCGACCTCCACGTTTACTAGGTCTCCCACCTGCGCATCCCCAAAGGTGGTTCGAGCAAGAGTTTCCGGAATAAGGGAAACCTCTGCCCAGCAATCCCCCACTTCAGAAACAGTGAGGGAAACACCATTGAGGGTGATGGAACCTTTATACGCAACAAAGCGAAGGGTGTCGGGGCTAAGGGAGATGCGGACAACGCGCTCTGAGTTGATGGAGGAGATAGGTGCGGTGGTGTCGACATGGCCTTGAACTATGTGGCCGCCAAGACGGTCTCCCACTGCGATAGCACGTTCAAGATTCACGACACTTCCAGGGATGAGAGTTCCCAGCGTGGTGAGACGGAGCGTTTCATGCATGACATCAGCAGCGAATCCGTTGGACAGAATGTCAACGACAGTGAGGCAGACACCGTTGACGGCAATGGAGTCGCCCAGGGCCGTTCCGTCCATTACAGTGGAACACTCGATGCTGACGCGTTGTAGGGGGCTATCCGGCGTGCCGCATTCCACCGCGTCGGCGAAGACTCCACGTTCTTCAACGATGCCTGTAAACACTAGAGCTTCCTCTCCAAAACGAGTTTGAGGTCTGCTCCTACTTTCTCACAACTCACAAACTGAAAGCGCTGTGCGTTCGGCAAGGTGTCAATAAGCGGGCTATGAGCAGCAGAGAGTCCCTGCCCGAGAATCATCGGAGCAGTGTACATCAATACTCGATCAGCATAGCCTCGGGCCAGGAGATCTCCCACCAACCGTGGGCCACCTTCCACCAAAACATCTTGATAGTCGGAGTCAGCAAAGTAGGTCAGTACATCCTCCCACTCCCGGGTACGGAGATGTGTCAAAGGCGCCGCAGCATACCCCTCGGAGATAGCGCAACTAGGAATTCCTGAAACATGAGTGAGCTCAACTTCGCCCGCTAATGCACTGGTACCAATAACATAGCGATGAGGTTGATGGGGGTAAAGGTTACCGTGCGGATCACGAGCTGTCAGCGCGGGGTTATCCGCTGCAAAGGTACCCGTTCCGACGACGATAGCGTCTACTCGTGACCGCTCGAGGTGCGCGTCGGCACGGGCTTCCTCACCAGTAATCCACTGGCTCGTGCCGTCAGCCGCAGCGGAAAAACCATCGAGGGTAGCAGCCATTTTAACGGTGACGCGAGGACGGCCTGTCTCTTGTTTATGAAGCCAGGCACCTAGACCACCTAGCCGAACCTGGGCTCGTTGGGCGTCATCGCCTTGTATACAGGTCACTCCACGCTCTGTGAGGTACTGTGCGCCGCCCCCAAACAAGGTAGTATCAGCGAAGACGTAATGCAACACCGTTATCCCTGCTTCCGCCAAGGCATGTGAACAGGGGCCTGTTTTCCCCCAACTATTACAGGGTTCGAGGGTAACGATAGCGGTCCCGCCACGTGCCGCCTCACCTGCCATCCGCAGAGCCTCGATTTCAGCATGAGGTCCACCAGGCGGTTGCGTGCACCCGATTCCGCACACATGCCCTTCTGCGTCAAGGATAGTAGCGCCGACAGGGGGGTTTGGAGTACTCAATCCGCGTGCATATTCAGCGGCACGGACGGCGAGCCAGAGGGCTTCTGATGGGCTGGCTGCTTGCCCCCGGCAAGAAAGGATAGTCTCTGGGAGTTGAGGAGACGATGTCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP012390|65878:73179|66829_68758_-|WP_053962609.1|DBSCAN-SWA
MGSPADFRPAPGTIPTKPGVYRFRDSYGRVIYVGKAKNLRNRLNSYFVSAENIRPLSRRMLSQAASVDWTVVANEGEALQLEWTWIQHFSPRFNIQFRDDKSYPLLAISSADTYPRVWVYRGARRKNVRYFGPYPKVGALRDTLDQLTKVFPVRTCTNGVFNRHTALGRPCLLGYIGKCCAPCVEQVELADYNALIVQLERFLTGQDKEIVRSLTAEMNEAAAALDFEKAARLRDHIAALQAVLEKQAVVLQETLDADVIGVATDEIEASVQLFRFRHGCIVGQQGWVVSKTGESDLGDWEDNVPDPALPYVVESFLPQFYNTHPGDIPRLILVPVLPPHAEELTEQLSTIRNSRVEIRQPQRGDLVRVMETVTENAAEALRQHKLKRASDLTSRSLALEELQTYLGLPQPPLRIECTDISHIQGTNVVASLVVFEDGLPRKSDYRTYLIKEAAGDGQSNDVGSIAEVTRRRFQHYREDARAVPDSAGSIADVPARRSVYPPQLFVVDGGAPQVAAAAGVLNELGITDLPVVGLAKRLEEVWVPEEEHPLILPRESEALYLLQRVRDESHRTAIGFHRKRRSKDMVASELERIEGVGPALHQALMNHFGTMKKLREANAEEIAAVPGFGPQRAKKVFAALHG
>NZ_CP012390|65878:73179|72072_73179_-|WP_082345248.1|DBSCAN-SWA
MTSSPQLPETILSCRGQAASPSEALWLAVRAAEYARGLSTPNPPVGATILDAEGHVCGIGCTQPPGGPHAEIEALRMAGEAARGGTAIVTLEPCNSWGKTGPCSHALAEAGITVLHYVFADTTLFGGGAQYLTERGVTCIQGDDAQRAQVRLGGLGAWLHKQETGRPRVTVKMAATLDGFSAAADGTSQWITGEEARADAHLERSRVDAIVVGTGTFAADNPALTARDPHGNLYPHQPHRYVIGTSALAGEVELTHVSGIPSCAISEGYAAAPLTHLRTREWEDVLTYFADSDYQDVLVEGGPRLVGDLLARGYADRVLMYTAPMILGQGLSAAHSPLIDTLPNAQRFQFVSCEKVGADLKLVLERKL
>NZ_CP012390|65878:73179|70761_71391_-|WP_053961317.1|DBSCAN-SWA
MSLFESIETAIEEFRQGRPVVVVDDDNRENEGDLIFPAAAATPELLAFMIRYTSGYICVGMDANICDRLALPIMWEKSEDRRLTAYTVSVDAAEGTTTGISAHDRALTIKKLGDPASVASDFHRPGHVLPLRAVAGGVFHRVGHTEAGSDLARLAGYEPVAALCEIVSEKDPTTMARREELREWCNRHKIAMISIADLAEWRRVHDPVQ
>NZ_CP012390|65878:73179|68763_69240_-|WP_053961316.1|DBSCAN-SWA
MAEAGRPGIATLDAAGMRVGIVAAQWNRDLCDQMLTRAREVAEQAGATVDVARVAGSIELPVVAQQFARTHDAVVAIGVVIRGDTAHFDYVCQSVTDGLTRVALDEATPVGNAVLTVNTVAQAHDRAGFADSVEDKGGEATFAALEVASELKRLRQVG
>NZ_CP012390|65878:73179|71476_72073_-|WP_053961318.1|DBSCAN-SWA
MFTGIVEERGVFADAVECGTPDSPLQRVSIECSTVMDGTALGDSIAVNGVCLTVVDILSNGFAADVMHETLRLTTLGTLIPGSVVNLERAIAVGDRLGGHIVQGHVDTTAPISSINSERVVRISLSPDTLRFVAYKGSITLNGVSLTVSEVGDCWAEVSLIPETLARTTFGDAQVGDLVNVEVDAIAKYVDHLLTPYK
>NZ_CP012390|65878:73179|65878_66712_-|WP_082345553.1|DBSCAN-SWA
MSGAGRGTAARLLEEFGWYVVDNLPMELIVRTAEITQNSKREIRRLAIVTDVRSQSFSGSLDFVVHELRSRGWSPRVLFLDASDEVLIRRYNQLRKTHPLQDKRPLEEGIKDERELLADLKNHADLVVDTSRLTSTKLRERLSEFRASGEKGLDIIVESFGFKYGIPLDADFVVDMRFLPNPYWVPALRPHSGMDADVAEYVLNNDVAEGFIESFAHMITLATPGYRAEGKAYVLLGVGCTGGKHRSVATTMELARRLGEAISDANVTAVHRDLGRE
>NZ_CP012390|65878:73179|69351_70716_-|WP_063665711.1|DBSCAN-SWA
MIEFDSIEQAIADFGIGQPVVVVDDENRENEGDLIFAAEKATPQLLAFMIRYTSGYICVGMDGELCDRLHLPAMVAHSEDPRKTAYTITVDAAQGTTTGISAADRARTIRTLADPVAGPASLNRPGHVLPLRAVSGGVLVRAGHTEASVDLARLAGLSPAGALCEIVSEKDPTTMARAVELREWCNHHKIAMISIKDLIQWRRQHEKLVERVTDANLPTKYGNFRIVGYRSLIDGQEHVAVVKGDVAADDGRDVLVRVHSECLTGDVFGSRRCDCGPQLHRSLDMIDAEGRGIVLYLRGHEGRGIGLLNKLRAYHLQDEGEDTVDANLKLGLPADAREYASAAQILYDLGVRSMRLLTNNPDKREGLEGYGVEITGRAHLPLDVTPENLTYLRTKRDRMGHALEDLDAVVGSATSDVQSSAWIDHDHTRTAVNEDAHHHCADGDCGCSHHQHSR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082345553.1|65878_66712_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.1e-05	33.9
WP_053962609.1|66829_68758_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_053961316.1|68763_69240_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2I2L4Y7	Orpheovirus	1.8e-10	34.8
WP_063665711.1|69351_70716_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	2.2e-88	43.5
WP_053961317.1|70761_71391_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-40	43.6
WP_053961318.1|71476_72073_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.1e-27	38.8
WP_082345248.1|72072_73179_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.2e-34	28.8

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP012390|99567:109995|DBSCAN-SWA
CCTACGCGCCCACAGCGGCAACTACAGTATCAACTGCAGCATATGCTGCCTCGAGTCCTTCTGCATCAGTACCGGAGCCTTGGGCCAGATCTGGTTTTCCGCCTCCGCGGCCACCAATGGTAGGGGCGGCGGCTTTCACGATGTCTCCGGCGTTCACTCCGCGTTCAATAGCCGCTTGGTTGACAGCCACAACGAAGGGCAGTTTATAGCCTTCTGCGGTAAAGAGCGCGACTACCGCTGGTGTCTCCGCGAATCGACCACGAATATCGCAGGCGAGGGTACGAAGTTGACCACCATCAGCACCAGCTGGGCCAGTCATGGCGACAACCTTAATACCGTTCACGTCATGGGCGTCGTTGACATATGTGGCGGCGGCCTGCAGAACTGCCTCCATATGTAGCTCGGCGAGTTCTTTTTCGAGGTTTTTGACCGACTCTTGCAGGCTACTTACGCGCTGTACGATATCGCCAGGCTTCGCCTTGAATCGCGAGGCTAGCTCGCTAACAATACGTTGATCAGTTTTTGCAGCATCTAATGCACGCAATCCGACATAGGCTTCGACACGCCGAATACCTGAGCCAACAGATGACTCTCCGATAAAGCGAACCGGTCCGATTTGTGCAGTAGAGCTTACGTGGGTGCCACCGCAGAGTTCCTTGGAGAAGACACGTTCCTCTCCTCCCCCAATGGTGACGACGCGAACTTCATCACCATAGTTTTCACCGAAGAGGGCGACAGCACCGGACGCTTTGGCCTCGTCCAGGCTCATGATCTCGGTTATTACCGGAAGATCCTGGTCAATCGCCGTGTTGACGCGAGTTTCGATTTCGGCAAGTTCCACGGTGCTCAATGGATCTGTCCAGTTAAAGTCAAACCGCAAATAACCCGGTTTATTGAGAGAACCAGCCTGTACAGCTTGGTCTCCCAACACGGTACGTATTGCCGCATGGACAAGGTGAGTAGCAGTGTGTGCTTGCGCAGCATGACGTCGGTAGGTTCCATCGACCTGTGCCTGGGCAGGTCCGGGGGCCGCCGTACCAATGGAGATAGTCCCTCGATGGAGCCAGACTTTCTTACCCACTTTTTGTACATCGGTGATGGCTACTTCTCCAGATGCTGTGGTGATGGTGCCGCGATCGGCACACTGCCCGCCGGACTCCGCGTAAAAGGGGCTCTCGCCGAGAATGACTTCGACTGCGGTGCCAACACTCGCTTCAGTCACTACGTCCCCATCGACGATAATGCCGAGAATCTGGGTATCGGCAACAAGACTCTCGTACCCCGTAAATTCGGTTGGCTGGTTATCGATGAAGTCTCGGTAGACCCCCACGTCAGCGTGTGCGTGTTTCTTTGCCTGTGAATCTGCCTTAGCGCGTTGCTTCTGCTCCTGCATCCGCTGTTGGAAGGCATCATTATCGACACTCAACCCCTGCTCCGCCGCCATCTCACGGGTGAGGTCGATGGGGAAACCGTGGGTGTCGTGCAAAGTGAAGGCCACATCACCAGGAACTACTGTCTGACCAGCGTCTTTGAGGTCACTTACAACGGCTGTGAAAAGCTTGGTGCCAGCATCAAGAGTCCGCAGGAAGGCTTTCTCCTCCGTGGTACACACTTTCTGGATATGGTCACGCTGCGCTGCCAGCTCGGGGAAGGAAGGTGTCATTGACTGACAGACGGTAGAGGTCAACTCCTGCATTACAGTACCCGTGGCTCCCAGCAGACGAGCTGAGCGAATGATACGGCGAATGAGGCGCCGCAGAATATAACCACGTCCCTCATTACCCGGGGACACTCCATCCGCAATGAGCATCACCGCGGTGCGCGAGTGATCAGCAATGACCCGGAAATACACCGCATTCTGATGATCCTCAGGGTCATCGCTATACGCTGTTCCTGTCAGGCACTCTGCCGTGGTGATAGTCGGCCTTAGAAGATCTGTTTCATAGACGTTTTCGACCCCCTGCAGAATAAAAGCAACGCGTTCGATGCCCATGCCGGTATCAATATTCTTCTGAGGTAGAGATCCGACAACTTCGTAACCGTCTTTGCCGATGCCTTCCCCACGTTCCTTTTCCATGAAGACAAGGTTCCAGATTTCGATATAGCGATCCTCGTCCACTACCGGACCGCCTTCTTTACCATAGGCAGGACCACGGTCAAAGAAAATTTCGGAGGACGGACCACAAGGGCCGGGCACACCCATCGACCAAAAGTTGTCCTTCATACCACGCCGTTGAATATGGTCTTCGCGGAGTCCTACGACGTCGCGCCAGATCGCGAATGTTTCATCATCATCTTGGTAGACAGTCGCCCACAACAGGTCCGGGTCGAATCCATAACCACCTTCGTTAACTGGACTGGTCAGGAGAGTCCAGGCGTGCGTGATGGCACCTTCTTTAAAGTAGGCACCGAAAGAGAAATTACCCGCCATCTGGAAGAACGTGTTGTGGCGAGTAGTGATACCCACCTCGTCGATATCAAGCGTACGGACGCATTTTTGGATGGAGGTTGCTGTTGCGAATGGAGCAGCTTGTTGCCCCAGAAAGTAAGGCTTAAAGGGAACCATGCCGGCGTTAACGAACAACAGGGTGGGATCATCAAGCACAAGCGAAGCAGAAGGAACAAGCGTATGCCCAGCCTTCACATAGTGGTCAATGAAACGTTGCCGAATTTCATGGGTGTACACGGATGAGATCCTTTTCCCTTTAAGCACCACGCTGCACCCATTCCGGTCGCCCCATCATCACGATGTGGCACCACACAAAGGCAGCGGCAGTTCTACAGTGTGCGTGTATCGTTTTCTAGCTTCTTAGCTTACCTGGTAAAGCAACGGGACCCATCACCTGAGCTTGTAGCTGGACCGAAGGCTACCTATCTCTTTTGGGTCTCCCACGCACCGCTGCACGCAATTTGGGCAGCCAGCTGGCAATCCGCTTCTCCGCTCCGTGCTCCGTGGGATGGTAATAATCTTTACCCACGAGGTTATCCGGAGGATACTGCTGTGCCAGAATGCCGTCGGCAGTATGGTGTGGATACTGATAGCCAATAGCATTGCCCAGCTTTTTCGCCCCCTCATAATGGCCATCCCGCAGATGTGGAGGCACCGGGCCGATATTATGTCCCTCTCGAACATCTGCAAGAGCAGCGTCGATAGCGGCGTAACACGCATTAGATTTAGGCGCAGTCGCCAGGTGGACCGTCGCTTCCGCAAGGATGATGCGGCCCTCCGGCATCCCGATCATCTGCACTGCTTGTGCTGCTGCTACAGCAGTGTGCAATGCGGTTGGATCCGCTAGCCCTATATCCTCCGCAGCAAGAATCATCAAGCGTCGCGCAATAAATCGGGGATCTTCCCCGGCACTTATCATGCGGGCCAAGTAGTGAAGTGCGGCATCGGGGTCGGATCCACGCACGGACTTAATGAAGGCACTAATGATGTCGTAATGCTGATCGCCATTGCGGTCATAGCGCGCTAATGCATCCGGTGTTGAACGCTCAATATCCGCGACAGTAAGTGGCGCAGTAACGTCCACCCGGGCATCCGCCGCCGCTTCCAGGTAGGTTAATGCACGCCGCGCGTCCCCTCCCGACAATCGAACGAGATCGGTGTATGACTCTTCTTCAACCGTCAGAGCCCCGCCAAAGCCACGCGGATCACTAACTGCCCGTTCTAAGACACCCCGCACATCTGCTGGAGAAAGCGACTCCAATTGCAATACAAGCGAGCGGGATAGTAGTGGAGCTACTACAGAGAACGAGGGGTTCTCTGTAGTAGCAGCAACCAAGAGCACTACGCGGTTTTCTACGGCAGCAAGAAGCGCTTCTTGCTGGGTTCGGGAGAAACGATGAACTTCATCAATGAACAGCACCGTATTAATACCGCGAATAAGCCGAGTTCGGGCATCAGAGATAACCTGCCGAACATCCTTGACACCTGCTGAAAGCGCTGACAGTTCAACGAATTCGCGTTCGGTTGCCCCAGAAATGAGACTCGCTAGCGTAGTTTTCCCAGTACCTGGTGGACCGAACAGGATAACAGAATTTGCACCTCCGCCTTCGATAAGCCGACGAAGCGGAGACCCCGGTTTGAGGAGGTGCTGTTGCCCCATCACTTCATCAAGAGTGCGGGGGCGCATCCGTACGGCTAACGGCGTATTGTCGCGCTGCGAACGCGAAGAGTTCGAGGGTCCCACAGACGATACTGGAGGTGCTAAAGACGCCGTTACGTAGGATTCTGCAGTGGAGTTGTGCACGGTAAAGAGACCAAGATCATTCTCATCCATGAGGCCTCCTTTGTCGTCGCTTAGGCGTGGTTCGCTAATGCCGCAGCCACATCACGAGCGTGCTGAGCAAGCTCAGCGTCCTCCCAGTACTCTGCCAGCGTACCAAGCTGGCGAAGTATGCGAATGGCGAGAGACCGAAGAATGATTTCCGTGCCCGCATTATCTTTACCCGTTGCATGTTCGAAGTCGCTGTCTTCATCAAGAACCCAGCTCACACTCAACCATGCCCAGGTAAGCGCGCCATCGAGAATGCGTTTGTGGGACGACTGCGGACGACGCATCCGGGGCCACATCGCATCCACCTGCTCTACCCAGGTCTGAGTAACAGCGTCAATTTCCTCAGTGGTCAGTTGATATCCGCGCAAATCGGAGGGGAACCCCAGCAGAATTGCTGCAACATCAACCCCAATATCTCGATATCCGCAGAACGCGAAGTCCAATAGTTGCACATTATGTTGTGTGACGAGAATATTTTCCGGGATCAGCTCTGCCGCGCTAAAGGCACGATAACTTCCTTGAACTGCGCGTTTCACGCTGCGCTTCCCCCGGTCCTGGACAGACTCAGCCAGGTGAATTCCCAACTTTTCCCGCAACAACAGAGGGACACCCTCTAGTGTGTCTGCCAAAAGATGTGAGGAAAATGGCACGACGAGACCAGGAGTCTTTGCCTGTGCACGATGGAGCAAGGCATGGAAATCGTCTTCTCGGCCAGCAGTAGATACTTGCATCGTGCCAATATGTGCTGCCAGGTCCCGTAACGCAGTCAGCGTTGCAGCAGTATGTGCACCGTGGTTAAAGACATCGTAAAGAGTGCGGGTGTTCCCTACATCCGAGAGAACGAACGCTCGTTCGGCAAAGTCGTAGGCAATAAGTTCTGGCCCAAAACTGTCTGGGGTACCGAGTGAGCCCACAAACTGATAGCCCACAATTTCGCGAAGCAATAGCCCGTCGCGTTCTTCCCCACGGTCGGGGAATACCTTCACGACGACTTTTCGAGATGGAAGAAATGGACTATCGGTGGTTATGCCACGAACGAGAATGGCGTCGGAATCCGACTCGATACGCTCGGTGTGCGAAAGAGTAACCGGGCTGCCAACCCGGGCACTGAGAATTCGCTCACCGAGCGCTATCGCGTCATCAACAGTGTTAGTCATTGTCCTTAGTAGCTTCACGCTTCTCTCCGCGATCTCCGGACCGGACCGGCTTCGCGTCGATCCCAGATTCCTTACGCTGCTGAGGAGTAATGGGAGCGGGAGCGTTCGTCAGCGGGTCGACACCGCCACCTGACTTAGGGAAGGCGATGACGTCTCGGATAGACTCTTCGCCTGCCAGCAACGCGGTAATACGGTCCCAACCGAAGGCCATCCCACCGTGCGGCGGCGCACCATATTTGAAGGCATCGAGAAGGAAGCCGAACTTCTCCTGTGCTTCCGGCTCACCGATACCCATCACTTTAAAGACACGCTCCTGTACGTCGCGTCGATGGATACGGATGGAACCGCCACCGATTTCATTGCCATTGCAGACAATGTCGTAGGCGTACGCCAGCGCAGTGCCGGGATCCGTGTCAAAGGTATCCATAGACTCCGGCTTCGGAGAAGTAAATGCGTGATGGACAGCAGTCCATGCAGAGTTGCCCAAAGCGACGTCACCGGAAGCGGTAGCGTCCGCAGAGGGTTCAAAGAGCGGTGCGTCGACAACCCACGTAAAGGCCCAGTCACCGTCCTTGATAAGACCAAGCTTCTTAGCAATCTCGTTGCGAGCGGCACCCAGCAGAGCCCGTGAGGACTTTGCGTCACCGGCAGCGAAGAAAATGCAGTCGCCTGGCTCAGCGTTCACATGAGCTGCGATGCCTTCACGCTCTTCAACAGAGATGTTCTTCGCAACAGGGCCAGACAGCTCTCCATCCTCGCCCACCAGAATGTAGGCGAGTCCCTTGGCACCACGCTGCTTTGCCCACTCTTGCCAGGCGTCAAGCTGACGACGAGGCTGAGAAGCTCCGCCCTTCATGACGACAGCACCCACGTAGGGGTTCTGGAATACCCGGAAGGGTGTGTTCTGGAAGAAGTCAGTACACTCCACGATCTGAATATCGAAACGCAGGTCAGGCTTGTCGGAACCGTAGAGACGCATAGCATCTGCATATGTCATGCGCGGGATGGGAGTAGTGATCTCGTAGCCAATGAGCTTCCACAGGTTGACGAGAATCTCTTCAGCCAAGGCAATGATGTCTTCCTGGTCGATAAAACTCATCTCGATATCAAGCTGCGTGAACTCGGGCTGCCGGTCAGCACGGAAGTCCTCGTCGCGGTAGCAGCGAGCAATCTGGTAATAACGCTCCATACCAGCGACCATCAGTAGCTGTTTAAATAGCTGCGGTGACTGTGGCAACGCATAGAACGTGCCCGGTTGAAGACGTGCCGGCACGAGGAAGTCACGAGCACCTTCAGGAGTGGACCGCGTCATGGTCGGAGTTTCGATCTCCACGAAGTCGTGCTTCGCTAGTACCTCACGTGCAGCAGCGTTGACTTTAGAGCGCAGCCGGAGATCGTAAGCAGGCTGATCACGCCGTAGGTCAAGATACCGGTAGCGGAGCCGAACTTCTTCACCAGGCTCATCATCAAGCTGGAACGGCAGCGGCGCGCAACTGTTGAGAACTTCCAGTTCTGCGACATTAACCTCAATCTCGCCGGAAGCTAGGTTCGGGTTCTCAGACCCCTCCGGACGAGCCTCCACGACACCAGTAACCTTGATGCAGTACTCAGAGCGCAGGTGGTGGGCTTGTTCTGCGACTGTGGAATTGCGGAACACCACCTGGGCGATGCCCGAGGAGTCCCGCAGATCCACGAAAATAACGCCACCGTGGTCACGGCGACGAGCAACCCAACCAGCGAGGGTAACAGTCTGTCCAGTAGCAGCGGCGTTCAGTTCGCCGGCGAAATGCGTGCGCAGCACGAGAATCCTTCCATGCTGAAAGTTATCAAAAAGCCTTAGGCATACGTTGACCTAGTCTACTCGTTTCCCTGCAGGCAGCCGAACTCACTTCGTCCGCCTCACCATAATTTTGTAGAAGAGTTTGCCGGTTTGAGAAGCATGTTCGCGCCCGCACATTAGTTGCGGATCCTCTCCGCAGTAGCCCGTCAATCGGGTAATTTCATCTGCAGATAGTGCAAAGGAGCGCACAATGACTTTCCAAACTGGCGGTAACCTCTCTGGTGGCCGAGTCTCTGCAGGTGGAGGCCGTGGCGGACTCGTTATTGGAGGCGGGCTAGGGACTATTGCTCTTGTCCTGGTAGCAGTATTCTTTGGGGTGGATCCACAAGCTATTCTGCCTGCTATCCAGGGCAGTGAGGGTTCTCAGCAAAACGCTGCTGCGGTCCAAGACCTGCAGAATCGTATTGACCGCTGTAAGAAGAGCGACTCGGCAGCGGCAAACGAGGATCCTGTCTGCCGTATTGTGGCGACAACGATCAGCGTGGATGCCATTTGGGGGGAACAGCTCCCCCGCCAAATGGATACGCAATATCGACGTCCCAACACCGTCATCTTCGATCAAGCTGTGAATACCGCCTGTGGTACGGCAAGTGTTGAAACCGGGCCTTTCTATTGTTCAGGCGACAATACCGCCTACTTCGATCTGAGCTTTTTTGAGACGATGCTGACCCGTTTGGGAGGTGTCAATGCGCCAGCCGCGCAGGAATATGTGGTTGCCCACGAATACGGTCACCATGTCCAAAATGTTCTTGGCTGGTTGACTCAAGACCGTATGCGCAGCAGTGGCCCTAATTCCTCACAAGTTCATCTCGAACTGGAAGCAGACTGTTTTGCGGGCCTGTGGTTCCACTATGCGTCTCGTCCTGGCAACCAGCCTTCTGACGCACCAATGTTGAAACCGCTCACCAATGACGAATTGCAATCGATTAGGGTCACTGCCCAAGCGATTGGTGACGATGCTATCCAGGAAGGTGCTGGTCAGCAGGTAAATCCCGAAAGATGGACCCACGGGTCATCACAGCAACGCCTCAATGCTTTCATGACGGGCTATAACAATGGGTCTATAGAGCGGTGCCACGCTTTAGGACGTTAGCACCACACGTGTGAACTTAAGAACGAGAAAACGAGGTGGGTAGCGTATTACGTCTACCCACCTCGTCATGAACAACTCAACTAGTAAGGATCAACCTACCAGGCTTTCACGCCTGAAGTGTACGCGACACCGTTGAAGTTACCTCGGATTGCACAACCTCATGCTGTTCACCCGTACGGAGATCCTTCACCACTACCGTTCCATTAGCCATCTCATTCTCTCCAACGACCAGCGCAAGAACGGCACCAGACTTATCGGCGGCTTTGAACGCCCCCTTCATCCCACGTGACCCAAACACCATATCGGTACGAATACCGGCTCCACGGATATCAGCAAGAAGTGGTATCAACGTTTCTTTTGCTGCCTCGCCCAGCGGGACGCCGAATACTTCACAGTGTGCCTCCGAGCCTGGTACGCATCCTTCTTCTTGGCAGGCCAAAAGAATACGGTCGACACCCAGCCCAAAACCAATTCCAGAGAGAGGCTGACCGCCAAGTACTTCCATTAGTCCGTCATAGCGGCCCCCACCACCAATGCCAGATTGTGCGCCCAGCCCATCATGAACAAACTCAAAAGTTGTCTTGGTGTAGTAGTCGAGGCCGCGGACCATCCGCGAATTCACGACATAGTCAACACCCACCGTGTCGAGAATACGCAGTACAGACTCAAAGTGGTGACGGCACTCGTCGGAAAGATAATCCAGCATGAGCGGAGCGTCAGCGGTCATCTCCCGTACCTCAGGACGTTTGTCGTCCAATACCCGCAGTGGGTTAATCTCCGCCCGCCGACGAGTCTCCTCATCTAGCGGTAGGTCGAACAGAAATGCCTGCAGGGATTCCCGGTAGGCCGGTCGACAGGTCTGGTCACCCAAGCTTGTCAGCTCAAGACGATACCCCCGCAGGCCCAAGCTTCGCAGCGCACTGTCTGCCATCGAGATAACTTCTGCGTCCAAAGCAGGGTCATCGACGCCAATAGCTTCTGCGCCAACTTGTTGGAGCTGCCGGTAGCGGCCTGCCTGCGGACGTTCGTAACGGAAGAATGGCCCAGCATAGGTGAGCTTGAGGGGAAGCTGACCACGGTCAAGATTGTGTTCAATCACAGAACGCATAACTCCGGCCGTTCCCTCCGGACGAAGTGTTAGTGAGCGGCCAGAACGATCAGAGAAGGTGTACATCTCTTTCGTCACCACGTCGGTAGATTCACCGACCCCACGAGCGAATAGACCAGTATCTTCAAACATCGGAAGTTCGATGTGTGAATAGCCGTAGTTTCGGATGGTAGTGATAAGAGTCTCGCGGACAGCCTGGAAGTGCGCCGACAGTGGAGGGAAGTACTCGGGCACGCCTTTGGGAGCTCGAAATGATACGGCAGCTGATCCTTTAGCCATCCTCACGTTCTTTCTTTTCAATAGCGATACTGCTGTCTATTATGTCGTATTCTGGTCGCTTTACCGGAAGCGACGCAGATAGACATTGTCGGCACGTTCGGCCGCCATCGTGCTGGTTTCTCCGTGTCCGGGGGCGACAAGTACGTCTCCGGGCAGCGGAATAAGCTCCCGCTCGATCGAATCAAGCAAGGTCTGCGCATCGCCGCCAGGTAAATCAGTGCGTCCCACCGCCCCTTTAAACAGGGTATCTCCGGAAAAGAGGACCGTCGGGGCAGAAGAGCCATCAGAGATAAGCAAACCGACGCCACCCGGAGTATGTCCTGGCAACGGGAGCACCTTTACAGTGAGATCAGCCGCAGTAAACTCCTCGTCGCAATACGTGAAAAGACTCTCTGGTGCATGCCATGATGAGAAGGGGAAGAGTGTCGACAATGTCGGGCCAACTCCTGCCGCCGGGTCCTCCACCATAAACACATCGTCGCGGTGCACAATCACGGGAATCTCATACGTGGCTGACAACTCCGGGGTACTCCAGATATGGTCTGCGTGGCCATGGGTGAGGTAGATCCCTACCGGGTTCAGTCCGTTGTCACTAATGAGTTTGCACACCGGCGAATAGGCTTCCTGCCCCGGATCAATGATGATGCAGTCATCATTAGAATCACTTGCCAC

Protein sequences of DBSCAN-SWA_2

>NZ_CP012390|99567:109995|102433_103849_-|WP_053961340.1|DBSCAN-SWA
MDENDLGLFTVHNSTAESYVTASLAPPVSSVGPSNSSRSQRDNTPLAVRMRPRTLDEVMGQQHLLKPGSPLRRLIEGGGANSVILFGPPGTGKTTLASLISGATEREFVELSALSAGVKDVRQVISDARTRLIRGINTVLFIDEVHRFSRTQQEALLAAVENRVVLLVAATTENPSFSVVAPLLSRSLVLQLESLSPADVRGVLERAVSDPRGFGGALTVEEESYTDLVRLSGGDARRALTYLEAAADARVDVTAPLTVADIERSTPDALARYDRNGDQHYDIISAFIKSVRGSDPDAALHYLARMISAGEDPRFIARRLMILAAEDIGLADPTALHTAVAAAQAVQMIGMPEGRIILAEATVHLATAPKSNACYAAIDAALADVREGHNIGPVPPHLRDGHYEGAKKLGNAIGYQYPHHTADGILAQQYPPDNLVGKDYYHPTEHGAEKRIASWLPKLRAAVRGRPKRDR
>NZ_CP012390|99567:109995|99567_102252_-|WP_053961339.1|tRNA|DBSCAN-SWA
MYTHEIRQRFIDHYVKAGHTLVPSASLVLDDPTLLFVNAGMVPFKPYFLGQQAAPFATATSIQKCVRTLDIDEVGITTRHNTFFQMAGNFSFGAYFKEGAITHAWTLLTSPVNEGGYGFDPDLLWATVYQDDDETFAIWRDVVGLREDHIQRRGMKDNFWSMGVPGPCGPSSEIFFDRGPAYGKEGGPVVDEDRYIEIWNLVFMEKERGEGIGKDGYEVVGSLPQKNIDTGMGIERVAFILQGVENVYETDLLRPTITTAECLTGTAYSDDPEDHQNAVYFRVIADHSRTAVMLIADGVSPGNEGRGYILRRLIRRIIRSARLLGATGTVMQELTSTVCQSMTPSFPELAAQRDHIQKVCTTEEKAFLRTLDAGTKLFTAVVSDLKDAGQTVVPGDVAFTLHDTHGFPIDLTREMAAEQGLSVDNDAFQQRMQEQKQRAKADSQAKKHAHADVGVYRDFIDNQPTEFTGYESLVADTQILGIIVDGDVVTEASVGTAVEVILGESPFYAESGGQCADRGTITTASGEVAITDVQKVGKKVWLHRGTISIGTAAPGPAQAQVDGTYRRHAAQAHTATHLVHAAIRTVLGDQAVQAGSLNKPGYLRFDFNWTDPLSTVELAEIETRVNTAIDQDLPVITEIMSLDEAKASGAVALFGENYGDEVRVVTIGGGEERVFSKELCGGTHVSSTAQIGPVRFIGESSVGSGIRRVEAYVGLRALDAAKTDQRIVSELASRFKAKPGDIVQRVSSLQESVKNLEKELAELHMEAVLQAAATYVNDAHDVNGIKVVAMTGPAGADGGQLRTLACDIRGRFAETPAVVALFTAEGYKLPFVVAVNQAAIERGVNAGDIVKAAAPTIGGRGGGKPDLAQGSGTDAEGLEAAYAAVDTVVAAVGA
>NZ_CP012390|99567:109995|103869_105003_-|WP_053961341.1|DBSCAN-SWA
MTNTVDDAIALGERILSARVGSPVTLSHTERIESDSDAILVRGITTDSPFLPSRKVVVKVFPDRGEERDGLLLREIVGYQFVGSLGTPDSFGPELIAYDFAERAFVLSDVGNTRTLYDVFNHGAHTAATLTALRDLAAHIGTMQVSTAGREDDFHALLHRAQAKTPGLVVPFSSHLLADTLEGVPLLLREKLGIHLAESVQDRGKRSVKRAVQGSYRAFSAAELIPENILVTQHNVQLLDFAFCGYRDIGVDVAAILLGFPSDLRGYQLTTEEIDAVTQTWVEQVDAMWPRMRRPQSSHKRILDGALTWAWLSVSWVLDEDSDFEHATGKDNAGTEIILRSLAIRILRQLGTLAEYWEDAELAQHARDVAAALANHA
>NZ_CP012390|99567:109995|109383_109995_-|WP_158408622.1|DBSCAN-SWA
MASDSNDDCIIIDPGQEAYSPVCKLISDNGLNPVGIYLTHGHADHIWSTPELSATYEIPVIVHRDDVFMVEDPAAGVGPTLSTLFPFSSWHAPESLFTYCDEEFTAADLTVKVLPLPGHTPGGVGLLISDGSSAPTVLFSGDTLFKGAVGRTDLPGGDAQTLLDSIERELIPLPGDVLVAPGHGETSTMAAERADNVYLRRFR
>NZ_CP012390|99567:109995|108042_109323_-|WP_053961344.1|tRNA|DBSCAN-SWA
MAKGSAAVSFRAPKGVPEYFPPLSAHFQAVRETLITTIRNYGYSHIELPMFEDTGLFARGVGESTDVVTKEMYTFSDRSGRSLTLRPEGTAGVMRSVIEHNLDRGQLPLKLTYAGPFFRYERPQAGRYRQLQQVGAEAIGVDDPALDAEVISMADSALRSLGLRGYRLELTSLGDQTCRPAYRESLQAFLFDLPLDEETRRRAEINPLRVLDDKRPEVREMTADAPLMLDYLSDECRHHFESVLRILDTVGVDYVVNSRMVRGLDYYTKTTFEFVHDGLGAQSGIGGGGRYDGLMEVLGGQPLSGIGFGLGVDRILLACQEEGCVPGSEAHCEVFGVPLGEAAKETLIPLLADIRGAGIRTDMVFGSRGMKGAFKAADKSGAVLALVVGENEMANGTVVVKDLRTGEQHEVVQSEVTSTVSRTLQA
>NZ_CP012390|99567:109995|107033_107936_+|WP_053961343.1|DBSCAN-SWA
MTFQTGGNLSGGRVSAGGGRGGLVIGGGLGTIALVLVAVFFGVDPQAILPAIQGSEGSQQNAAAVQDLQNRIDRCKKSDSAAANEDPVCRIVATTISVDAIWGEQLPRQMDTQYRRPNTVIFDQAVNTACGTASVETGPFYCSGDNTAYFDLSFFETMLTRLGGVNAPAAQEYVVAHEYGHHVQNVLGWLTQDRMRSSGPNSSQVHLELEADCFAGLWFHYASRPGNQPSDAPMLKPLTNDELQSIRVTAQAIGDDAIQEGAGQQVNPERWTHGSSQQRLNAFMTGYNNGSIERCHALGR
>NZ_CP012390|99567:109995|104995_106804_-|WP_053961342.1|tRNA|DBSCAN-SWA
MLRTHFAGELNAAATGQTVTLAGWVARRRDHGGVIFVDLRDSSGIAQVVFRNSTVAEQAHHLRSEYCIKVTGVVEARPEGSENPNLASGEIEVNVAELEVLNSCAPLPFQLDDEPGEEVRLRYRYLDLRRDQPAYDLRLRSKVNAAAREVLAKHDFVEIETPTMTRSTPEGARDFLVPARLQPGTFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFIDQEDIIALAEEILVNLWKLIGYEITTPIPRMTYADAMRLYGSDKPDLRFDIQIVECTDFFQNTPFRVFQNPYVGAVVMKGGASQPRRQLDAWQEWAKQRGAKGLAYILVGEDGELSGPVAKNISVEEREGIAAHVNAEPGDCIFFAAGDAKSSRALLGAARNEIAKKLGLIKDGDWAFTWVVDAPLFEPSADATASGDVALGNSAWTAVHHAFTSPKPESMDTFDTDPGTALAYAYDIVCNGNEIGGGSIRIHRRDVQERVFKVMGIGEPEAQEKFGFLLDAFKYGAPPHGGMAFGWDRITALLAGEESIRDVIAFPKSGGGVDPLTNAPAPITPQQRKESGIDAKPVRSGDRGEKREATKDND

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053961339.1|99567_102252_-|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.5e-61	35.4
WP_053961340.1|102433_103849_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	2.6e-84	43.3
WP_053961341.1|103869_105003_-	hypothetical protein	NA	NA	NA	NA
WP_053961342.1|104995_106804_-|tRNA	aspartate--tRNA ligase	A0A2K9L0E9	Tupanvirus	2.3e-05	36.5
WP_053961343.1|107033_107936_+	neutral zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	2.6e-45	43.2
WP_053961344.1|108042_109323_-|tRNA	histidine--tRNA ligase	A0A1V0SLE3	Klosneuvirus	2.4e-20	24.8
WP_158408622.1|109383_109995_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.7e-16	30.7