CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LN881739	Streptomyces venezuelae genome assembly Streptomyces venezuelae ATCC 15439, chromosome : I	7 crisprs	c2c9_V-U4,csa3,WYL,DEDDh,DinG,cas3,c2c10_CAS-V-U3,Cas14u_CAS-V,cas4	11	10	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LN881739_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN881739_1

1652491-1652700

Orphan

Consensus_repeat	Method
CCGGGTACGCCGGAGGCGCGGGC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_LN881739_1

>merge|NZ_LN881739|1|1652491-1652700|CRISPRCasFinder
CCGGGTACGCGGGCGGGGCGTCGAGGGCAGGGATCTCCCCCGGGTAGGCAGGGGGAGCGTCCCCGGGGAAGGCGGAGACGGCCTGGCCCGAGGGCGCGGAGGGAACGGCGTCACCCGGGTAGGTCGGCGGAGGGATCTCCCCCGGATACGCGGGAGGAGCGTCCTCCGGGAAGAGCGCGGCATCGCCCGGGTACGCGGGCGCGGCGTCAT

>NZ_LN881739|1|1|1652491-1652700|CRISPRCasFinder
CCGGGTACGCGGGCGGGGCGTCG	AGGGCAGGGATCTCCC
CCGGGTAGGCAGGGGGAGCGTCC	CCGGGGAAGGCGGAGACGGCCTGGCCCGAGGGCGCGGAGGGAACGGCGTCAC
CCGGGTAGGTCGGCGGAGGGATC	TCCCCCGGATACGCGGGAGGAGCGTCCTCCGGGAAGAGCGCGGCATCGC
CCGGGTACGCGGGCGCGGCGTCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN881739.1\|WP_055640336.1\|1657378_1658236_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235777
NZ_LN881739.1\|WP_055640334.1\|1653657_1654866_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|166942
NZ_LN881739.1\|WP_079037876.1\|1643784_1644744_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_LN881739.1\|WP_055640329.1\|1648934_1649546_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_LN881739.1\|WP_079037313.1\|1642995_1643766_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239322
NZ_LN881739.1\|WP_055640335.1\|1655015_1657382_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640332.1\|1650736_1651198_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_LN881739.1\|WP_055640339.1\|1659923_1661645_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|238625
NZ_LN881739.1\|WP_055645904.1\|1661968_1663174_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640330.1\|1649734_1650304_-\|YceI-family-protein	unknown	unknown	gnl\|CDD\|377274
NZ_LN881739.1\|WP_055640327.1\|1646771_1647317_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640325.1\|1645085_1645976_-\|iron-containing-redox-enzyme-family-protein	unknown	unknown	gnl\|CDD\|379634
NZ_LN881739.1\|WP_055645905.1\|1663215_1664784_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|379243
NZ_LN881739.1\|WP_055640338.1\|1659133_1659892_-\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NZ_LN881739.1\|WP_055640328.1\|1647306_1648491_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|275255
NZ_LN881739.1\|WP_055640331.1\|1650322_1650652_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_LN881739.1\|WP_055645903.1\|1653112_1653607_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055645906.1\|1664812_1665523_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640326.1\|1645972_1646770_-\|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl\|CDD\|188630
NZ_LN881739.1\|WP_055640337.1\|1658390_1659077_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736

Protein	Function_ID	Function_description	E-value
NZ_LN881739.1\|WP_055640334.1\|1653657_1654866_-\|hypothetical-protein	gnl\|CDD\|166942	PRK00404, tatB, Sec-independent protein translocase subunit TatB.	0.00685549
NZ_LN881739.1\|WP_079037876.1\|1643784_1644744_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.65034e-16
NZ_LN881739.1\|WP_055640329.1\|1648934_1649546_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	2.35574e-13
NZ_LN881739.1\|WP_055640336.1\|1657378_1658236_-\|hypothetical-protein	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	1.8329e-06
NZ_LN881739.1\|WP_055640332.1\|1650736_1651198_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.11715e-11
NZ_LN881739.1\|WP_055640339.1\|1659923_1661645_-\|amidohydrolase	gnl\|CDD\|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	2.19852e-128
NZ_LN881739.1\|WP_055640330.1\|1649734_1650304_-\|YceI-family-protein	gnl\|CDD\|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	1.35251e-56
NZ_LN881739.1\|WP_079037313.1\|1642995_1643766_-\|hypothetical-protein	gnl\|CDD\|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	6.81503e-11
NZ_LN881739.1\|WP_055640325.1\|1645085_1645976_-\|iron-containing-redox-enzyme-family-protein	gnl\|CDD\|379634	pfam14518, Haem_oxygenas_2, Iron-containing redox enzyme. The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.	1.18282e-28
NZ_LN881739.1\|WP_055640338.1\|1659133_1659892_-\|LuxR-family-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.34051e-17
NZ_LN881739.1\|WP_055640328.1\|1647306_1648491_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|275255	TIGR04462, PLP-dependent_aminotransferase, enduracididine biosynthesis enzyme MppP. Members of this family are MppP, one of three enzymes involved in synthesizing enduracididine, a non-proteinogenic amino acid used in non-ribosomal peptide synthases to make natural products such as enduracidin from Streptomyces fungicidicus ATCC 21013. MppP is a PLP-dependent enzyme, predicted by homology to be an aminotransferase.	3.61977e-56
NZ_LN881739.1\|WP_055640331.1\|1650322_1650652_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	6.94151e-17
NZ_LN881739.1\|WP_055645905.1\|1663215_1664784_+\|VWA-domain-containing-protein	gnl\|CDD\|379243	pfam13531, SBP_bac_11, Bacterial extracellular solute-binding protein. This family includes bacterial extracellular solute-binding proteins.	6.83792e-13
NZ_LN881739.1\|WP_055640326.1\|1645972_1646770_-\|dihydrodipicolinate-synthase-family-protein	gnl\|CDD\|188630	cd00408, DHDPS-like, Dihydrodipicolinate synthase family. Dihydrodipicolinate synthase family. A member of the class I aldolases, which use an active-site lysine which stabilizes a reaction intermediate via Schiff base formation, and have TIM beta/alpha barrel fold. The dihydrodipicolinate synthase family comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways and includes such proteins as N-acetylneuraminate lyase, MosA protein, 5-keto-4-deoxy-glucarate dehydratase, trans-o-hydroxybenzylidenepyruvate hydratase-aldolase, trans-2'-carboxybenzalpyruvate hydratase-aldolase, and 2-keto-3-deoxy- gluconate aldolase. The family is also referred to as the N-acetylneuraminate lyase (NAL) family.	4.8932e-52
NZ_LN881739.1\|WP_055640337.1\|1658390_1659077_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.4677e-41

>NZ_LN881739.1|WP_055640332.1|1650736_1651198_+|MarR-family-transcriptional-regulator
MVMREGEYRVEAWRALLLAHNAAVRAIESDVQRNGRIPLTWYDVLLELRGAGEQGLRMQEVAERVVLSRTRVSRLVDEMARSGLVTKEPDPTDKRVTWAVITDEGRSALRATAPAYMRGIREHFGRYLTDEEAAVITTALLRVAHSGDDIQLG
>NZ_LN881739.1|WP_055640331.1|1650322_1650652_-|rhodanese-like-domain-containing-protein
MAQRISRDELKKKIDENLVTVLEALPAQYYNDKHLPGALNLPHDQVDALAPTLLPNKDAEIAVYCANSPCPNSGIAADRLVELGYTNVYEYYEGKDDWVEAGLPTESVA
>NZ_LN881739.1|WP_055640330.1|1649734_1650304_-|YceI-family-protein
MTTAPIRTVDGVELPAAGPWKIDPGHAEVGFVGRHFMLTKVRGRFTGVEATLVIGERPEDSKVTAVIDVASVDSGDATRDEHLRSADLFDVEKYPKAVFASTSVTWDGRRGTLVGDLTIKDVTRPVTLAVDYLGYARDPWGNDRTVFSAHGKVNREDWGLTWNMVLESGGILVSKEIELSLEFEAIRES
>NZ_LN881739.1|WP_055640329.1|1648934_1649546_+|TetR/AcrR-family-transcriptional-regulator
MQHVSPDSSPLAAPEAPPERSDAARNRLRILAAAGALFDAHGVESVSMDRIAAEAGVGKGTLFRRFGSKAGLAAALLDAQDSRLQERILFGPPPLGPDAPAADRILAFFDAYLDLLDENLELLRLSETAAPGARYRIGSYGFWRVHLALMLRETCPDLDADCTAHLLLAPLDSDLQHALRQGQFTPERVRSALLTLVRRVIAG
>NZ_LN881739.1|WP_055640328.1|1647306_1648491_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MTAHAGTTLSSQELLDLTQHEIQALLTEFNLADAHTHQRQSAAQHKIVARLPELWYEAEEGLQATYEQRFIEAFFRLHRQPTALAKNKTLLSYAASISTMVVAMYLKQQRMAVTLVEPCFDNLHDVLSNMGVPLYPVEESALHDPDRIYAELKRRVRTDALFLVDPNNPTGFSLMHSGRKGFEEVVRFCKDHNKLLIIDFCFASFTLYDPELARFDVYELLEESGVRYLAIEDTGKTWPVQDAKAAMLTASDDIKEEVYNLHTSVLLNVSPFVLNMLTQYVENSEADDLASIRDVLDINRVAVKEALQGTILEYQEPIAKTSVAWARIQHPDLTATELQRELREVGVYILPGRFFYWSQPGRGEPFVRMALAREPEMFAGAMKRLREVLDRHER
>NZ_LN881739.1|WP_055640327.1|1646771_1647317_-|hypothetical-protein
MSADDTATARDDFIDAALFLGMHSADDTVRVAAKAFFVRHLDGRVVMSLEQVGRCDDVIWGYSRELQDLYYPFMDHLHTVMDISREGYDRADVHLALSDTDTPRQLPFIDRMLLGQVINRKGLLHTVGPRSAAFDGLPVRTVTDWPVGQPEPTFPEPLERLYRESLALRLPVGTGALSEGA
>NZ_LN881739.1|WP_055640326.1|1645972_1646770_-|dihydrodipicolinate-synthase-family-protein
MNQGVIAALVTPFSETGEVSESGVARLLDTLRPHVDALLPNLSTGEGRRLTDRQWEDMLRATVKHAGELPVLAGVLRPTTEQVLERARTAADLGAHGLVATSPYGTGVTQAEIYRHFADLAEHSGLPVVVYHGTEVSGNAADFDTLLRICALPSVVGVKDSSGSSEFTRRLVGARPGARVLAGLEHLLLESGAVDGYVVALANVEPALCADLFAGRLADPAGSLTAACERYGLEKDDWYRWVKTELYRRGVLENDRTVDTGEVPS
>NZ_LN881739.1|WP_055640325.1|1645085_1645976_-|iron-containing-redox-enzyme-family-protein
MSVAAKTVETVPATRSARTEAESVHRELFRHNRSVLDSHLLARVEEIERDWIAPLVDSLDSTGEPVPDRASWQRLLDGLLADERAGSPSGDYLADHASREEFTFVVREFALDGLTEAQNFFPAVPRLPIKAQMAVMRVLIDEFGCGNLQQAHSQLYRLLLAELGLPQEPESFLDTTGDETFQFLNVFYWLTQRAPHVEYFLGALAYLEASIPDAFTHQARACERLGIRQGRYYTEHLHIDTFHMQEMQLAIKECETAYGLDPARLWTGARLLSALIGDAFDAAVARARELTGRAAA
>NZ_LN881739.1|WP_079037876.1|1643784_1644744_-|methyltransferase-domain-containing-protein
MLGDDLRMTAFRTAIAEAVRPGDVVLDLGTGTGILARWALEAGAARVYGIDLNENVLATAAERLAEAGFADRFVPLSGLSFDLELPERVDIVISEIMGNLADNENFSAILDDARERFLRPGGTMLPGLVDSFLVPVTAETAHAQLTGEGPRDAGGPEAFAGLLAARGAESPFSLYYDTVLPIAGHLASPRLIRRYDPAPAAAAGTETSYRVPLAYTVQRDGVFTGFKGYFVAQLSESVALDISGDDIEGRTTSDSWKHCYLPIERPVRVRRGDRIALTFARRGGRDGDPFGQTYSWEGQVLSGTRVVDRFAHSTGPAAD
>NZ_LN881739.1|WP_079037313.1|1642995_1643766_-|hypothetical-protein
MTDRTTDRTTIRATDGTAAEERGRAADPRLPAAPDTIAVYTDLNCSFAHVAVHRLHETRRRLGLEGRVWFDLRAFPLELFNREVNARPGVDSEISVLGALEPEAGWRLWQGPDWTYPVTTLPALEAVHAAKDQSRHASEQLDRALRRAFWAEGRCISQRHVILDVAGETGAVDVTALAEVFDSGTARPAVMAQYASARDGRVNCSPHLFLHDGTDCANPGIRARWVNGDFGTGFPVIDEDRPEIYEKLLTQAADLL
>NZ_LN881739.1|WP_055645903.1|1653112_1653607_-|hypothetical-protein
MSPGAAERLLGELRQEAVRADTKGSILVAAQGMAAAALVGVLAARGWHPTDLSGLGQVLWWAGAGCFLVSLTALLMAVVPRYRTVGWQPGDPLTHFADIRGAARRGQEVLEEALRDTDRAPRAAVIASLMENSRIVSIKYDWLRVGIAGFTVALVLLPGALLAG
>NZ_LN881739.1|WP_055640334.1|1653657_1654866_-|hypothetical-protein
MMSQPPQWQQEANRHTALVDPVVTIQELSRFKPLRATRIDHALVFTTAQGGRDTYLPPSRPSRTELATKRWTSVYEVDMGRHEAATVLAFPSRRDAFLFEVSLSCTWQVVDPAAFVASGERNVPALAQRLVEDAVRPVLRGFDMEDSAAAESHARKAVEAAGPLAARAGLDVRCGLQIRRDEAALEQERQMREIAFAREKLEPQHALLMREDELAAERALVQGRQQHRIDFQQQDLDHERSLARGRQELELQEIEAKKIEYYAYYLERGGPAAMAFQLARHPEDARLVMENLRQDQLLAMKNQLTVAIQALGGGPGGLEEHQMDEPRRLAANVIKEVLGAKLSPGPVQPQPAVDAAAVEGGGAPAAAPVEDQVPGAPETAQAPPPPEDGPVFGYHTQPQPPR
>NZ_LN881739.1|WP_055640335.1|1655015_1657382_-|hypothetical-protein
MTTPQEHQDSPDGQGPYAERAAVDPHAPEGTGDTATGTEDPAGTENETEYAWDSRRDLYRHSPGIMLGHSARVGGSLVGGDQHGVSGGQVTGDVILGGSKVEYHLGGDTEERSGEIPASEVEALAGNFVHPMGGEEAGAERASAAAPADGGHDGDLPHEPWQPGSPFALALAGLREHRVAILSGPATTGRRAAALMLLRAVGSPSYRALDPALPPGRLAGELREGCGHLVADFATTAERPLREHHIRALSERLHATGSHLVVVVGPHPVVHGSVSPVPWEPPEPAALLAGHLRHKDLAGRSVDELLALAEVRAVLAHHRPVADTARFAERVAGHARGSVSLAELGAFGHYAAERQVREWFDSADHSLHDKAFLIALATFDEAPYPLTAELSDVLFALLQRIENPGEPARIPVFGTSSAQRVEQALADRYQEPEETEWGPVLQTKVQFRDRLTAITLLREVWTGHPSSRPALVAWLRRLADDPRPVVRTRAAATAAVMAAADLPSAMALLIRSWAADRRLRARLAAANALALAHHLGAPHVSRILAEWCVAPDHRLRWTAVRGYALVGDAFPEEALAALTEAVRALEARGGPAEGWSNERDDLAQSAAALLLAAGQEAAARDDWDAVARLWGAFPPLLRGATRDYVLRATVYAAGPTDGPVGTGRPLLLDLFARADATPGTDGAVLRHALAALWRGVLNDPVCSASGLNTLRQWVRAAEDDRGAEAALAELLPLLAVSTEDHKRLVYLLENLRSEGDSAPPSVALRLRALVLVSTPPHGDARPRRPSPA
>NZ_LN881739.1|WP_055640336.1|1657378_1658236_-|hypothetical-protein
MREPVNRTILLIDVERFSRRDDVVQAVLRRTFNKIVDQTLEAAGVEATQQYREDRGDGLIVLLSGDVAKTVILRSLLTTTPELLHEHNLLASESAQMRMRIVLAAGEVAHDPHAGTTGGLVGHDLNQACRLLDADVLRSALAERADEHCVLAVSAPVYEGVVRHGHRGVRPELFRRADVAVKDGVLPAWIHQGAAPDRDPEAAAATPAPAPAAPAPAPAPAPAPAPAPQQPSAGAVFHFHGGAPVIHGSLVGGDQNGVSGGQVTGDVVLGGTRAAADDPADGSRS
>NZ_LN881739.1|WP_055640337.1|1658390_1659077_-|Crp/Fnr-family-transcriptional-regulator
MTQFEDQVPFVARLDTEDRHALFRGGGHLAFPARQVLLREHEPSTHVLVILSGWAKVTSAAPNGYEALLALRGPGDIVGEQALLSGRPRGATVIALEPVEALAVDAERFGALLDERPSIARKLLALTADRTRDSDRRRVQFASLAVQERLALLLLELIRTHGEESEDGVQLTAGLTQSELAGSVGASREAVARLLKQLRERGIVRTGRRGIVVVRPDVLRQMARSGGG
>NZ_LN881739.1|WP_055640338.1|1659133_1659892_-|LuxR-family-transcriptional-regulator
MAAERSTADILDAAVHVREAARSATSGATGIDTVLAALSEVMEYDHASLARWDPLRRRHTTLAGSYPDDATAYIETRLHHDPVFPVLRGPDRGGLWLRDVPRQLLAASPGFQEVLSPLGIEDGVAQCLFAADGRYVGMLNVSTRRPRRTPDPARAVVTLLTESLAAAVDARERPRPGGLSPRELQVLAELTVGRTNREIAERLFITPRTVGTHIEHILAKLDLPNRAAAAARAAAWGIEPVNRHGPPGAAMR
>NZ_LN881739.1|WP_055640339.1|1659923_1661645_-|amidohydrolase
MDTYADLVFVGGRVVTVDAEFSVASALAVTGGIIGAVGGRDDVAPLIGPATRVVDLRGATLLPGINDSHLHGCAFGMASPPLSLDVAHPAVSSLADVAEVVGEAVGRVRAGQWITGHGWDTGYLDECVSDPSRQPSLHDLDAVSPDHPVVLYSFSGHATWVNSKALELIGIDRHTVAPPGGAIVVDEAGEPTGLLHEGAQALVQNALPPLSRQERTDAIRSTLATLARLGVTSYTEPGLGPGGDGIMRGALGGETLDAYRRLLADGELTARVGVLLLPTGMASTAEEFARGLDALGAAEGPESPHDADPRRLAIHGVKIFGDGIVPNKTAWMHEPYVGGGCGSLCVGGETDADRIAEIGAMIRHAHAAGYQLGVHVTGDRAGDTVVDAFAAAVAEHPRPGARHYVIHGDFLTAHGMKVLAAHDFGVNMNPTIKWTVADMEEEFVGAGRAAYAWPYRDALDAGVRVASGSDAPVTHPDWRQGVATMMLRESKATGRVSGPEQRIGLAEAIRTYTIDAAWQDFADDWKGSLEPGKAADLCVLDGDLLTADPHDIPEMAVVLTVVDGRVVHDTLRD
>NZ_LN881739.1|WP_055645904.1|1661968_1663174_+|hypothetical-protein
MTVRRRSSGSWSRRSLLLFLLPVLATVLTGLATLTISGNLLLPFERVVVLEGKMASKRDFFEDEEVRRILLKHHISVHITSSGSREVAMRDIAAFDFVFPSGQPAGDLITGVRAADGRYAKVHRPFVSPIALATYREYAETLRDAGIATPLPSEGADRPLYYSLDMRKFLDGIDRGKRWNDLGIRRHGIANANRIVAQSPDVCGSNSAGTYLALVSFTWRGDGPDVPTTDQEASSRARSVKHLMEQGLPAADVFRTYISPDGKGIAPVVVAYEHQYLTYQVRHRAETGRLDSERVLLYPSSQFVTQPQFISLNSKGDRLGELVTTDPDLRRRAMELGFRILDPAGEVAGDQLARFLTERNVPVPALRGDDTRSPMPRIRYLERMISIVGDCPVAPLPDQAR
>NZ_LN881739.1|WP_055645905.1|1663215_1664784_+|VWA-domain-containing-protein
MTALALAWLAVLATLASCTSDSPEPVTLRVLASSELADMEPMFDDLRRDTGITLEMEYQGTVEAAASLAAGRYRHDLAWLSSSRPFQLLLRKHGRQTESPLSTSTMRSPVVVGLKPEVAQRLRRTAPDGQLSWADLADAAAAGTLKYAMADPRSSNSGLSALVGVATAAAATGGALRPEDVSCDRLRGFFAGHKLTVDSSGGLAGAYARAEGGLDALITYESELLALNRAGTLRAPLELVYPKDGIVLSDYPLMLLDPGRRDAYDRLTAWLRSEAVQRKIMERTLRRPITPDLPRIPSLWTPLGNALYFPDDQAVVDRLLADYAAARSGGPARVLFLLDFSTSMRGERIANLRATFDGLSGADDSRSGKFARFHRGETLTVLRFGGRVLDERSVTYGKADDLERLRGFVADDGFAAGTAVWSALDHAYRSAADALAKDSRQRVSIVLMTDGENNAGMSLDTFLGRYAALPPAARAVRTYTVRYGDSDPRELDRAARATGGHMADATGQSLLNAFKEIRGCHE
>NZ_LN881739.1|WP_055645906.1|1664812_1665523_+|hypothetical-protein
MLLWAVTGAGLATLLSVTLLRLVRVRRTVTPDITDGICFYLHDKMVMDHYQMRSYTAALRKEVEQRTSDSKDGTVRAKVFGVGADGGRKENTEVVSRYLEVAEPISVIGLIMKVLEEKRVIVHVDLPSRSVTRSTALLRTTAGARDDVQLRDVEGFVLIRGRYRATGAEGPTTVFLAPYGDPADPSQGPRVRVTCATEGLRTQVPPGTFSARCLGKVQEWNAAEGVLEVQAMAIFR

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Crispr_ID: NZ_LN881739_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN881739_2

1652758-1653020

Orphan

Consensus_repeat	Method
CCGGGTACGCCGGAGGCGCGGGC	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_LN881739_2

>merge|NZ_LN881739|2|1652758-1653020|CRISPRCasFinder
CCGGATACGCAGGCGGTGCACTCTCCCCCGGATACGCGGGCGCAACCGCCTCTCCCGGGTACGCCGGAGGCGCGGGCTCGTCCGGGTACGCCGGAGGCGCGGGCTCGTCCGGGTACGCCGGAGGCGCGGGCGGTGCCGGGGCATCGGCCGGATAGGCAGGGGGTGTTTCCCGCTCGCCCGGGTACGGGGGCGGGGGCGGGACCTGCCCTCCCGGGTAGGGCGGCGGCGGGACTTCCTCCCCCGGGTACGGCGGAGGCGGGACG

>NZ_LN881739|2|2|1652758-1653020|CRISPRCasFinder
CCGGATACGCAGGCGGTGCACTC	TCCCCCGGATACGCGGGCGCAACCGCCTCTC
CCGGGTACGCCGGAGGCGCGGGC	TCGTCCGGGTACGCCGGAGGCGCGGGCTCGT
CCGGGTACGCCGGAGGCGCGGGC	GGTGCCGGGGCATCGGCCGGATAGGCAGGGGGTGTTTCCCGCTCGC
CCGGGTACGGGGGCGGGGGCGGG	ACCTGCCCTCCCGGGTAGGGCGGCGGCGGGACTTCCTCCC
CCGGGTACGGCGGAGGCGGGACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN881739.1\|WP_055640334.1\|1653657_1654866_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|166942
NZ_LN881739.1\|WP_079037876.1\|1643784_1644744_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_LN881739.1\|WP_055640329.1\|1648934_1649546_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_LN881739.1\|WP_055645906.1\|1664812_1665523_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640325.1\|1645085_1645976_-\|iron-containing-redox-enzyme-family-protein	unknown	unknown	gnl\|CDD\|379634
NZ_LN881739.1\|WP_055640335.1\|1655015_1657382_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640332.1\|1650736_1651198_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_LN881739.1\|WP_055640339.1\|1659923_1661645_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|238625
NZ_LN881739.1\|WP_055645904.1\|1661968_1663174_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640330.1\|1649734_1650304_-\|YceI-family-protein	unknown	unknown	gnl\|CDD\|377274
NZ_LN881739.1\|WP_055640327.1\|1646771_1647317_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640336.1\|1657378_1658236_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235777
NZ_LN881739.1\|WP_055645905.1\|1663215_1664784_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|379243
NZ_LN881739.1\|WP_055640338.1\|1659133_1659892_-\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NZ_LN881739.1\|WP_055640328.1\|1647306_1648491_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|275255
NZ_LN881739.1\|WP_055640331.1\|1650322_1650652_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_LN881739.1\|WP_055645903.1\|1653112_1653607_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_152335207.1\|1651210_1652746_-\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320696
NZ_LN881739.1\|WP_055640326.1\|1645972_1646770_-\|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl\|CDD\|188630
NZ_LN881739.1\|WP_055640337.1\|1658390_1659077_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736

Protein	Function_ID	Function_description	E-value
NZ_LN881739.1\|WP_055640334.1\|1653657_1654866_-\|hypothetical-protein	gnl\|CDD\|166942	PRK00404, tatB, Sec-independent protein translocase subunit TatB.	0.00685549
NZ_LN881739.1\|WP_079037876.1\|1643784_1644744_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.65034e-16
NZ_LN881739.1\|WP_055640329.1\|1648934_1649546_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	2.35574e-13
NZ_LN881739.1\|WP_055640336.1\|1657378_1658236_-\|hypothetical-protein	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	1.8329e-06
NZ_LN881739.1\|WP_055640332.1\|1650736_1651198_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.11715e-11
NZ_LN881739.1\|WP_055640339.1\|1659923_1661645_-\|amidohydrolase	gnl\|CDD\|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	2.19852e-128
NZ_LN881739.1\|WP_055640330.1\|1649734_1650304_-\|YceI-family-protein	gnl\|CDD\|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	1.35251e-56
NZ_LN881739.1\|WP_055640325.1\|1645085_1645976_-\|iron-containing-redox-enzyme-family-protein	gnl\|CDD\|379634	pfam14518, Haem_oxygenas_2, Iron-containing redox enzyme. The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.	1.18282e-28
NZ_LN881739.1\|WP_055640338.1\|1659133_1659892_-\|LuxR-family-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.34051e-17
NZ_LN881739.1\|WP_055640328.1\|1647306_1648491_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|275255	TIGR04462, PLP-dependent_aminotransferase, enduracididine biosynthesis enzyme MppP. Members of this family are MppP, one of three enzymes involved in synthesizing enduracididine, a non-proteinogenic amino acid used in non-ribosomal peptide synthases to make natural products such as enduracidin from Streptomyces fungicidicus ATCC 21013. MppP is a PLP-dependent enzyme, predicted by homology to be an aminotransferase.	3.61977e-56
NZ_LN881739.1\|WP_055640331.1\|1650322_1650652_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	6.94151e-17
NZ_LN881739.1\|WP_055645905.1\|1663215_1664784_+\|VWA-domain-containing-protein	gnl\|CDD\|379243	pfam13531, SBP_bac_11, Bacterial extracellular solute-binding protein. This family includes bacterial extracellular solute-binding proteins.	6.83792e-13
NZ_LN881739.1\|WP_152335207.1\|1651210_1652746_-\|M48-family-metalloprotease	gnl\|CDD\|320696	cd07337, M48B_HtpX_like, Peptidase M48 subfamily B HtpX-like membrane-bound metallopeptidase. This HtpX family of peptidase M48 subfamily B includes uncharacterized HtpX homologs and consists of proteins smaller than Ste24p, with homology restricted to the C-terminal half of Ste24p. HtpX expression is controlled by the Cpx stress response system, which senses abnormal membrane proteins. HtpX participates in the proteolytic quality control of these misfolded proteins by undergoing self-degradation and collaborating with FtsH, a membrane-bound and ATP-dependent protease, to eliminate them. HtpX, a zinc metalloprotease with an active site motif HEXXH, has an FtsH-like topology, and is capable of introducing endoproteolytic cleavages into SecY (also an FtsH substrate). However, HtpX does not have an ATPase activity and will only act against cytoplasmic regions of a target membrane protein. Thus, HtpX and FtsH have overlapping and/or complementary functions, which are especially important at high temperature; in E. coli and Xylella fastidiosa, HtpX is heat-inducible, while in Streptococcus gordonii it is not.	9.13199e-29
NZ_LN881739.1\|WP_055640326.1\|1645972_1646770_-\|dihydrodipicolinate-synthase-family-protein	gnl\|CDD\|188630	cd00408, DHDPS-like, Dihydrodipicolinate synthase family. Dihydrodipicolinate synthase family. A member of the class I aldolases, which use an active-site lysine which stabilizes a reaction intermediate via Schiff base formation, and have TIM beta/alpha barrel fold. The dihydrodipicolinate synthase family comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways and includes such proteins as N-acetylneuraminate lyase, MosA protein, 5-keto-4-deoxy-glucarate dehydratase, trans-o-hydroxybenzylidenepyruvate hydratase-aldolase, trans-2'-carboxybenzalpyruvate hydratase-aldolase, and 2-keto-3-deoxy- gluconate aldolase. The family is also referred to as the N-acetylneuraminate lyase (NAL) family.	4.8932e-52
NZ_LN881739.1\|WP_055640337.1\|1658390_1659077_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.4677e-41

>NZ_LN881739.1|WP_152335207.1|1651210_1652746_-|M48-family-metalloprotease
MPAYPEGDVAPAYPGDDAAPAYPGDAALFPEDAPPAYPGEIPPPTYPGDAVPSAPSGQAVSAFPGDAPPAYPGEIPALDAPPAYPEAVSAAGLLGAAADVQTALRDGGPPAYDGEGSSPAVPAPRAGGDVAQVASVDGSLPAAPAAPPGTVASHDDLALDHGRRMVKSVQRGIDGAALSHLLVTLPIGFISLGVVTFLSALVNPVLAVVVPVVWLLSGPLVFHRKVESAIARRLFGMRRPTPEEAQRLDLVWEQVTRRAGVDRETYELWIQERTELNSTAAAGHIVAVTRHAMDRLPNSRLGAVLAHELGHHVGGHTWAAMLADWYALPARAAGRAVVLLLFVLFRTKHWAGIACGGCLTLMIVQLLFVFTFVQGYWWFVLPVAAAPLFVAWLHRRAEFRADAYAVGLGFGQALETVLVDEARATAVPGLPPQGQGTAPVPTPLPPGPPPFPRQQYPGQQHPGVPHPVPPGPVTGKAGGRGIAARAAHTNTEARLRNVRLVMSQQVQRSAP
>NZ_LN881739.1|WP_055640332.1|1650736_1651198_+|MarR-family-transcriptional-regulator
MVMREGEYRVEAWRALLLAHNAAVRAIESDVQRNGRIPLTWYDVLLELRGAGEQGLRMQEVAERVVLSRTRVSRLVDEMARSGLVTKEPDPTDKRVTWAVITDEGRSALRATAPAYMRGIREHFGRYLTDEEAAVITTALLRVAHSGDDIQLG
>NZ_LN881739.1|WP_055640331.1|1650322_1650652_-|rhodanese-like-domain-containing-protein
MAQRISRDELKKKIDENLVTVLEALPAQYYNDKHLPGALNLPHDQVDALAPTLLPNKDAEIAVYCANSPCPNSGIAADRLVELGYTNVYEYYEGKDDWVEAGLPTESVA
>NZ_LN881739.1|WP_055640330.1|1649734_1650304_-|YceI-family-protein
MTTAPIRTVDGVELPAAGPWKIDPGHAEVGFVGRHFMLTKVRGRFTGVEATLVIGERPEDSKVTAVIDVASVDSGDATRDEHLRSADLFDVEKYPKAVFASTSVTWDGRRGTLVGDLTIKDVTRPVTLAVDYLGYARDPWGNDRTVFSAHGKVNREDWGLTWNMVLESGGILVSKEIELSLEFEAIRES
>NZ_LN881739.1|WP_055640329.1|1648934_1649546_+|TetR/AcrR-family-transcriptional-regulator
MQHVSPDSSPLAAPEAPPERSDAARNRLRILAAAGALFDAHGVESVSMDRIAAEAGVGKGTLFRRFGSKAGLAAALLDAQDSRLQERILFGPPPLGPDAPAADRILAFFDAYLDLLDENLELLRLSETAAPGARYRIGSYGFWRVHLALMLRETCPDLDADCTAHLLLAPLDSDLQHALRQGQFTPERVRSALLTLVRRVIAG
>NZ_LN881739.1|WP_055640328.1|1647306_1648491_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MTAHAGTTLSSQELLDLTQHEIQALLTEFNLADAHTHQRQSAAQHKIVARLPELWYEAEEGLQATYEQRFIEAFFRLHRQPTALAKNKTLLSYAASISTMVVAMYLKQQRMAVTLVEPCFDNLHDVLSNMGVPLYPVEESALHDPDRIYAELKRRVRTDALFLVDPNNPTGFSLMHSGRKGFEEVVRFCKDHNKLLIIDFCFASFTLYDPELARFDVYELLEESGVRYLAIEDTGKTWPVQDAKAAMLTASDDIKEEVYNLHTSVLLNVSPFVLNMLTQYVENSEADDLASIRDVLDINRVAVKEALQGTILEYQEPIAKTSVAWARIQHPDLTATELQRELREVGVYILPGRFFYWSQPGRGEPFVRMALAREPEMFAGAMKRLREVLDRHER
>NZ_LN881739.1|WP_055640327.1|1646771_1647317_-|hypothetical-protein
MSADDTATARDDFIDAALFLGMHSADDTVRVAAKAFFVRHLDGRVVMSLEQVGRCDDVIWGYSRELQDLYYPFMDHLHTVMDISREGYDRADVHLALSDTDTPRQLPFIDRMLLGQVINRKGLLHTVGPRSAAFDGLPVRTVTDWPVGQPEPTFPEPLERLYRESLALRLPVGTGALSEGA
>NZ_LN881739.1|WP_055640326.1|1645972_1646770_-|dihydrodipicolinate-synthase-family-protein
MNQGVIAALVTPFSETGEVSESGVARLLDTLRPHVDALLPNLSTGEGRRLTDRQWEDMLRATVKHAGELPVLAGVLRPTTEQVLERARTAADLGAHGLVATSPYGTGVTQAEIYRHFADLAEHSGLPVVVYHGTEVSGNAADFDTLLRICALPSVVGVKDSSGSSEFTRRLVGARPGARVLAGLEHLLLESGAVDGYVVALANVEPALCADLFAGRLADPAGSLTAACERYGLEKDDWYRWVKTELYRRGVLENDRTVDTGEVPS
>NZ_LN881739.1|WP_055640325.1|1645085_1645976_-|iron-containing-redox-enzyme-family-protein
MSVAAKTVETVPATRSARTEAESVHRELFRHNRSVLDSHLLARVEEIERDWIAPLVDSLDSTGEPVPDRASWQRLLDGLLADERAGSPSGDYLADHASREEFTFVVREFALDGLTEAQNFFPAVPRLPIKAQMAVMRVLIDEFGCGNLQQAHSQLYRLLLAELGLPQEPESFLDTTGDETFQFLNVFYWLTQRAPHVEYFLGALAYLEASIPDAFTHQARACERLGIRQGRYYTEHLHIDTFHMQEMQLAIKECETAYGLDPARLWTGARLLSALIGDAFDAAVARARELTGRAAA
>NZ_LN881739.1|WP_079037876.1|1643784_1644744_-|methyltransferase-domain-containing-protein
MLGDDLRMTAFRTAIAEAVRPGDVVLDLGTGTGILARWALEAGAARVYGIDLNENVLATAAERLAEAGFADRFVPLSGLSFDLELPERVDIVISEIMGNLADNENFSAILDDARERFLRPGGTMLPGLVDSFLVPVTAETAHAQLTGEGPRDAGGPEAFAGLLAARGAESPFSLYYDTVLPIAGHLASPRLIRRYDPAPAAAAGTETSYRVPLAYTVQRDGVFTGFKGYFVAQLSESVALDISGDDIEGRTTSDSWKHCYLPIERPVRVRRGDRIALTFARRGGRDGDPFGQTYSWEGQVLSGTRVVDRFAHSTGPAAD
>NZ_LN881739.1|WP_055645903.1|1653112_1653607_-|hypothetical-protein
MSPGAAERLLGELRQEAVRADTKGSILVAAQGMAAAALVGVLAARGWHPTDLSGLGQVLWWAGAGCFLVSLTALLMAVVPRYRTVGWQPGDPLTHFADIRGAARRGQEVLEEALRDTDRAPRAAVIASLMENSRIVSIKYDWLRVGIAGFTVALVLLPGALLAG
>NZ_LN881739.1|WP_055640334.1|1653657_1654866_-|hypothetical-protein
MMSQPPQWQQEANRHTALVDPVVTIQELSRFKPLRATRIDHALVFTTAQGGRDTYLPPSRPSRTELATKRWTSVYEVDMGRHEAATVLAFPSRRDAFLFEVSLSCTWQVVDPAAFVASGERNVPALAQRLVEDAVRPVLRGFDMEDSAAAESHARKAVEAAGPLAARAGLDVRCGLQIRRDEAALEQERQMREIAFAREKLEPQHALLMREDELAAERALVQGRQQHRIDFQQQDLDHERSLARGRQELELQEIEAKKIEYYAYYLERGGPAAMAFQLARHPEDARLVMENLRQDQLLAMKNQLTVAIQALGGGPGGLEEHQMDEPRRLAANVIKEVLGAKLSPGPVQPQPAVDAAAVEGGGAPAAAPVEDQVPGAPETAQAPPPPEDGPVFGYHTQPQPPR
>NZ_LN881739.1|WP_055640335.1|1655015_1657382_-|hypothetical-protein
MTTPQEHQDSPDGQGPYAERAAVDPHAPEGTGDTATGTEDPAGTENETEYAWDSRRDLYRHSPGIMLGHSARVGGSLVGGDQHGVSGGQVTGDVILGGSKVEYHLGGDTEERSGEIPASEVEALAGNFVHPMGGEEAGAERASAAAPADGGHDGDLPHEPWQPGSPFALALAGLREHRVAILSGPATTGRRAAALMLLRAVGSPSYRALDPALPPGRLAGELREGCGHLVADFATTAERPLREHHIRALSERLHATGSHLVVVVGPHPVVHGSVSPVPWEPPEPAALLAGHLRHKDLAGRSVDELLALAEVRAVLAHHRPVADTARFAERVAGHARGSVSLAELGAFGHYAAERQVREWFDSADHSLHDKAFLIALATFDEAPYPLTAELSDVLFALLQRIENPGEPARIPVFGTSSAQRVEQALADRYQEPEETEWGPVLQTKVQFRDRLTAITLLREVWTGHPSSRPALVAWLRRLADDPRPVVRTRAAATAAVMAAADLPSAMALLIRSWAADRRLRARLAAANALALAHHLGAPHVSRILAEWCVAPDHRLRWTAVRGYALVGDAFPEEALAALTEAVRALEARGGPAEGWSNERDDLAQSAAALLLAAGQEAAARDDWDAVARLWGAFPPLLRGATRDYVLRATVYAAGPTDGPVGTGRPLLLDLFARADATPGTDGAVLRHALAALWRGVLNDPVCSASGLNTLRQWVRAAEDDRGAEAALAELLPLLAVSTEDHKRLVYLLENLRSEGDSAPPSVALRLRALVLVSTPPHGDARPRRPSPA
>NZ_LN881739.1|WP_055640336.1|1657378_1658236_-|hypothetical-protein
MREPVNRTILLIDVERFSRRDDVVQAVLRRTFNKIVDQTLEAAGVEATQQYREDRGDGLIVLLSGDVAKTVILRSLLTTTPELLHEHNLLASESAQMRMRIVLAAGEVAHDPHAGTTGGLVGHDLNQACRLLDADVLRSALAERADEHCVLAVSAPVYEGVVRHGHRGVRPELFRRADVAVKDGVLPAWIHQGAAPDRDPEAAAATPAPAPAAPAPAPAPAPAPAPAPQQPSAGAVFHFHGGAPVIHGSLVGGDQNGVSGGQVTGDVVLGGTRAAADDPADGSRS
>NZ_LN881739.1|WP_055640337.1|1658390_1659077_-|Crp/Fnr-family-transcriptional-regulator
MTQFEDQVPFVARLDTEDRHALFRGGGHLAFPARQVLLREHEPSTHVLVILSGWAKVTSAAPNGYEALLALRGPGDIVGEQALLSGRPRGATVIALEPVEALAVDAERFGALLDERPSIARKLLALTADRTRDSDRRRVQFASLAVQERLALLLLELIRTHGEESEDGVQLTAGLTQSELAGSVGASREAVARLLKQLRERGIVRTGRRGIVVVRPDVLRQMARSGGG
>NZ_LN881739.1|WP_055640338.1|1659133_1659892_-|LuxR-family-transcriptional-regulator
MAAERSTADILDAAVHVREAARSATSGATGIDTVLAALSEVMEYDHASLARWDPLRRRHTTLAGSYPDDATAYIETRLHHDPVFPVLRGPDRGGLWLRDVPRQLLAASPGFQEVLSPLGIEDGVAQCLFAADGRYVGMLNVSTRRPRRTPDPARAVVTLLTESLAAAVDARERPRPGGLSPRELQVLAELTVGRTNREIAERLFITPRTVGTHIEHILAKLDLPNRAAAAARAAAWGIEPVNRHGPPGAAMR
>NZ_LN881739.1|WP_055640339.1|1659923_1661645_-|amidohydrolase
MDTYADLVFVGGRVVTVDAEFSVASALAVTGGIIGAVGGRDDVAPLIGPATRVVDLRGATLLPGINDSHLHGCAFGMASPPLSLDVAHPAVSSLADVAEVVGEAVGRVRAGQWITGHGWDTGYLDECVSDPSRQPSLHDLDAVSPDHPVVLYSFSGHATWVNSKALELIGIDRHTVAPPGGAIVVDEAGEPTGLLHEGAQALVQNALPPLSRQERTDAIRSTLATLARLGVTSYTEPGLGPGGDGIMRGALGGETLDAYRRLLADGELTARVGVLLLPTGMASTAEEFARGLDALGAAEGPESPHDADPRRLAIHGVKIFGDGIVPNKTAWMHEPYVGGGCGSLCVGGETDADRIAEIGAMIRHAHAAGYQLGVHVTGDRAGDTVVDAFAAAVAEHPRPGARHYVIHGDFLTAHGMKVLAAHDFGVNMNPTIKWTVADMEEEFVGAGRAAYAWPYRDALDAGVRVASGSDAPVTHPDWRQGVATMMLRESKATGRVSGPEQRIGLAEAIRTYTIDAAWQDFADDWKGSLEPGKAADLCVLDGDLLTADPHDIPEMAVVLTVVDGRVVHDTLRD
>NZ_LN881739.1|WP_055645904.1|1661968_1663174_+|hypothetical-protein
MTVRRRSSGSWSRRSLLLFLLPVLATVLTGLATLTISGNLLLPFERVVVLEGKMASKRDFFEDEEVRRILLKHHISVHITSSGSREVAMRDIAAFDFVFPSGQPAGDLITGVRAADGRYAKVHRPFVSPIALATYREYAETLRDAGIATPLPSEGADRPLYYSLDMRKFLDGIDRGKRWNDLGIRRHGIANANRIVAQSPDVCGSNSAGTYLALVSFTWRGDGPDVPTTDQEASSRARSVKHLMEQGLPAADVFRTYISPDGKGIAPVVVAYEHQYLTYQVRHRAETGRLDSERVLLYPSSQFVTQPQFISLNSKGDRLGELVTTDPDLRRRAMELGFRILDPAGEVAGDQLARFLTERNVPVPALRGDDTRSPMPRIRYLERMISIVGDCPVAPLPDQAR
>NZ_LN881739.1|WP_055645905.1|1663215_1664784_+|VWA-domain-containing-protein
MTALALAWLAVLATLASCTSDSPEPVTLRVLASSELADMEPMFDDLRRDTGITLEMEYQGTVEAAASLAAGRYRHDLAWLSSSRPFQLLLRKHGRQTESPLSTSTMRSPVVVGLKPEVAQRLRRTAPDGQLSWADLADAAAAGTLKYAMADPRSSNSGLSALVGVATAAAATGGALRPEDVSCDRLRGFFAGHKLTVDSSGGLAGAYARAEGGLDALITYESELLALNRAGTLRAPLELVYPKDGIVLSDYPLMLLDPGRRDAYDRLTAWLRSEAVQRKIMERTLRRPITPDLPRIPSLWTPLGNALYFPDDQAVVDRLLADYAAARSGGPARVLFLLDFSTSMRGERIANLRATFDGLSGADDSRSGKFARFHRGETLTVLRFGGRVLDERSVTYGKADDLERLRGFVADDGFAAGTAVWSALDHAYRSAADALAKDSRQRVSIVLMTDGENNAGMSLDTFLGRYAALPPAARAVRTYTVRYGDSDPRELDRAARATGGHMADATGQSLLNAFKEIRGCHE
>NZ_LN881739.1|WP_055645906.1|1664812_1665523_+|hypothetical-protein
MLLWAVTGAGLATLLSVTLLRLVRVRRTVTPDITDGICFYLHDKMVMDHYQMRSYTAALRKEVEQRTSDSKDGTVRAKVFGVGADGGRKENTEVVSRYLEVAEPISVIGLIMKVLEEKRVIVHVDLPSRSVTRSTALLRTTAGARDDVQLRDVEGFVLIRGRYRATGAEGPTTVFLAPYGDPADPSQGPRVRVTCATEGLRTQVPPGTFSARCLGKVQEWNAAEGVLEVQAMAIFR

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Crispr_ID: NZ_LN881739_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN881739_3

1844770-1845048

Orphan

Consensus_repeat	Method
CGGCCTCGGGCCGGGCGGGCTCCG	CRISPRCasFinder

5 spacers

The CRISPR arrays of NZ_LN881739_3

>merge|NZ_LN881739|3|1844770-1845048|CRISPRCasFinder
CTGGGGCGGGCCGGGCGAGCTGGGACGAGCCCGGGGCGGGCGGCGCACCTCCGGCCGGACGGGCCCGGGCCGGACGGGCCCGGGCCAGGCAGGGATCCGCTCAGCCGAGCCCAGGCCGGACAGACTCCGTCCGGACGGCACTAACGTCAGGCGGCCTCGGGCCGGGCGGGCTCCGCTCAGCTGGAGCTCCGCCCGGACGGAGCAGTCAGACGGCCTCGGGCCGGGCAGGCTCCGGCCGGGCGGGCTCGCGTCTGGCGCGCTCCGGCCGGGCGGGCTCGC

>NZ_LN881739|3|3|1844770-1845048|CRISPRCasFinder
CTGGGGCGGGCCGGGCGAGCTGGG	ACGAGCCCGGGGCGGGCGGC
GCACCTCCGGCCGGACGGGCCCGG	GCCGGACGGGCCCGGGCCAGGCAGGGATCCGCTCAGC
CGAGCCCAGGCCGGACAGACTCCG	TCCGGACGGCACTAACGTCAGG
CGGCCTCGGGCCGGGCGGGCTCCG	CTCAGCTGGAGCTCCGCCCGGACGGAGCAGTCAGA
CGGCCTCGGGCCGGGCAGGCTCCG	GCCGGGCGGGCTCGCGTCTGG
CGCGCTCCGGCCGGGCGGGCTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN881739.1\|WP_055640465.1\|1846660_1846963_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640458.1\|1838251_1839118_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640453.1\|1834112_1834733_+\|isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl\|CDD\|235156
NZ_LN881739.1\|WP_055645922.1\|1848457_1850494_-\|Xaa-Pro-dipeptidyl-peptidase	unknown	unknown	gnl\|CDD\|235435
NZ_LN881739.1\|WP_055640470.1\|1853977_1854979_+\|sphingomyelin-phosphodiesterase	unknown	unknown	gnl\|CDD\|132436
NZ_LN881739.1\|WP_055640468.1\|1852304_1853189_-\|DUF2236-domain-containing-protein	unknown	unknown	gnl\|CDD\|378343
NZ_LN881739.1\|WP_055640471.1\|1855007_1855493_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055640461.1\|1842307_1843042_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224956
NZ_LN881739.1\|WP_055640467.1\|1850713_1852285_+\|M1-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341066
NZ_LN881739.1\|WP_055640455.1\|1835538_1836282_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|119339
NZ_LN881739.1\|WP_055640456.1\|1836298_1836937_-\|DJ-1/PfpI-family-protein	unknown	unknown	gnl\|CDD\|153233
NZ_LN881739.1\|WP_055640462.1\|1843052_1844690_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_LN881739.1\|WP_055640464.1\|1845622_1846579_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|334462
NZ_LN881739.1\|WP_055640457.1\|1837100_1838072_-\|GlxA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227311
NZ_LN881739.1\|WP_055640459.1\|1839399_1841832_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NZ_LN881739.1\|WP_055640469.1\|1853330_1853819_-\|ATP-synthase-F0-subunit-B	unknown	unknown	gnl\|CDD\|180240
NZ_LN881739.1\|WP_055640463.1\|1845078_1845540_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_079037336.1\|1847081_1848452_-\|carboxypeptidase	unknown	unknown	gnl\|CDD\|349461
NZ_LN881739.1\|WP_099054349.1\|1834698_1835256_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|340413
NZ_LN881739.1\|WP_055640460.1\|1841909_1842311_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_LN881739.1\|WP_055640464.1\|1845622_1846579_+\|FAD-binding-oxidoreductase	gnl\|CDD\|334462	pfam01266, DAO, FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.	1.41685e-24
NZ_LN881739.1\|WP_055640453.1\|1834112_1834733_+\|isopentenyl-diphosphate-Delta-isomerase	gnl\|CDD\|235156	PRK03759, PRK03759, isopentenyl-diphosphate Delta-isomerase.	2.94832e-88
NZ_LN881739.1\|WP_055645922.1\|1848457_1850494_-\|Xaa-Pro-dipeptidyl-peptidase	gnl\|CDD\|235435	PRK05371, PRK05371, x-prolyl-dipeptidyl aminopeptidase; Provisional.	0
NZ_LN881739.1\|WP_055640470.1\|1853977_1854979_+\|sphingomyelin-phosphodiesterase	gnl\|CDD\|132436	TIGR03395, Sphingomyelinase_C, sphingomyelin phosphodiesterase. Members of this family are bacterial proteins that act as sphingomyelin phosphodiesterase (EC 3.1.4.12), also called sphingomyelinase. Some members of this family have been shown to act as hemolysins. [Cellular processes, Pathogenesis].	2.18272e-111
NZ_LN881739.1\|WP_055640468.1\|1852304_1853189_-\|DUF2236-domain-containing-protein	gnl\|CDD\|378343	pfam09995, DUF2236, Uncharacterized protein conserved in bacteria (DUF2236). This domain, found in various hypothetical bacterial proteins, has no known function. This family contains a highly conserved arginine and histidine that may be active site residues for an as yet unknown catalytic activity.	1.14389e-55
NZ_LN881739.1\|WP_055640461.1\|1842307_1843042_-\|hypothetical-protein	gnl\|CDD\|224956	COG2045, COG2045, Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only].	3.42861e-23
NZ_LN881739.1\|WP_055640467.1\|1850713_1852285_+\|M1-family-metallopeptidase	gnl\|CDD\|341066	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains mostly bacterial and some archaeal M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	2.01845e-158
NZ_LN881739.1\|WP_055640455.1\|1835538_1836282_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	9.5382e-63
NZ_LN881739.1\|WP_055640456.1\|1836298_1836937_-\|DJ-1/PfpI-family-protein	gnl\|CDD\|153233	cd03139, GATase1_PfpI_2, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	9.9334e-79
NZ_LN881739.1\|WP_055640462.1\|1843052_1844690_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	2.26097e-139
NZ_LN881739.1\|WP_055640457.1\|1837100_1838072_-\|GlxA-family-transcriptional-regulator	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	1.39495e-94
NZ_LN881739.1\|WP_055640459.1\|1839399_1841832_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NZ_LN881739.1\|WP_055640469.1\|1853330_1853819_-\|ATP-synthase-F0-subunit-B	gnl\|CDD\|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	5.67255e-23
NZ_LN881739.1\|WP_079037336.1\|1847081_1848452_-\|carboxypeptidase	gnl\|CDD\|349461	cd06242, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	4.48824e-69
NZ_LN881739.1\|WP_099054349.1\|1834698_1835256_-\|ATP-binding-protein	gnl\|CDD\|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	4.43449e-14

>NZ_LN881739.1|WP_055640462.1|1843052_1844690_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MTATLVAKDLAAGHGERTLFAGLDLVVAPGDVIGLVGVNGAGKSTLLRLLAGLDTPEEGELRLSPPTASVGHLPQEPERRAGETVREFLARRTGVLAAQTAMDEATQGLVDGTPGADDAYATTLERWLNLGGADLDERAEEVADSLGLTVGLDQPMTSLSGGQAARAGLASLLLSRYDVFLLDEPTNDLDLDGLERLEAFVKGLRAGTVVISHDREFLTRTVTKVLELDLAQQQITLYGGGYDAYLDERDTARRHAREDFEEYAGKKAALEARGHMQRSWMTQGVKNARRKATDGDKLGRNARSEASEKQASKARQTQRMIERLDVVEEPRKEWELRMEIAAAPRSGSVVATLREAEVRRGDFAFGPVTLQIDWADRVAVTGANGAGKSTLLAALLGRLPLDSGDTVVGSGVVVGEVDQARKLFHGTEKLLEAFCAAVPDTEPAEVRTLLAKFGLKAEHVLRPATTLSPGERTRAALALLQGRGVNLLVLDEPTNHLDLPAIEQLESALDSYTGTLLLVTHDRRMLDAVRTTRRIEVADGKVTEL
>NZ_LN881739.1|WP_055640461.1|1842307_1843042_-|hypothetical-protein
MTISFGWGPVEARALARAAACVVVVDVLSFTTSVGVAVEAGAAVHPYRWRDATAAAYADRVGATLAVGRGEATPDHPWTLSPAALRAAPMPPRLVLPSPNGSTIAAEAEGYGATVVAASLRNRTAVARWLADRGYGSADRPLAVIASGERWPDGSLRPALEDLLGAGAVLSALAGTGTPTPEASAAATLWTATEDPVAALHGCDSGRELYEYGFPQDVAVAAETDSSTTVPVLVDGAFQEASAP
>NZ_LN881739.1|WP_055640460.1|1841909_1842311_-|hypothetical-protein
MTDLLTRLTEMLDDLDSDVDETIDLADEIAASGDAGLLPRLQAELDRALTDRNAYARELLGGVLAAIGGPDALPTLIRASAVDLGDDQDGLAAEIVDLVQADPNTAAAVLRPLTEDDDLSIANRAEWALRFVP
>NZ_LN881739.1|WP_055640459.1|1839399_1841832_+|RNA-binding-transcriptional-accessory-protein
MTTSIEARIAEELGVRERQVKAAVELLDGGSTVPFIARYRKEATEMLDDAQLRTLEERLRYLRELEDRRAAILDSVREQGKLTEELEARIRAADTKARLEDIYLPFKPKRRTKAQIAREAGLTPLAEGLLSDPSVEPTAAAAAFVDADKGVADAAAALEGARAILTEKFSEDADLIGELRERMWGRGRLAAKVREGQEEAGSKFADYFDFAEPFTALPSHRVLAMLRGEKEDVLSLDLEPEEPSETPGPSSYEGIVAHRFGVADRGRPGDKWLQDTVRWAWRTRILVHLGIDLRLRLRTAAEDEAVRVFAANLRDLLLAAPAGTRATLGLDPGFRTGVKVAVVDATGKVVATDTIYPHVPANKWDQALDKLARLAKQHAVELVAIGNGTASRETDKLAAELLAKHPELNLTKVMVSEAGASVYSASAFASQELPDLDVSLRGAVSIARRLQDPLAELVKIDPKSIGVGQYQHDLAEVKLSRSLDAVVEDCVNGVGVDVNTASTPLLSRVSGISSGLAENIVAHRDANGPFRSRKALKDVARLGPKAYEQCAGFLRIRDGDDPLDSSSVHPEAYPVVRRMAKSTGGQVAALIGDTGTLRSLRAGDFVDETFGLPTVTDILRELEKPGRDPRPAFKTATFKEGVEKIGDLASGMILEGVVTNVAAFGAFVDIGVHQDGLVHVSAMSRTFVKDPRDVVKPGDVVKVKVMDVDIPRKRISLTLRLDDEAGADAQGGAPKRGERGGDRADRGGRPPQQRQGGGAGGGGGGGRRSERGGRDDRGGRDRSSAPAPGNSAMADALRKAGLLGEGGKRK
>NZ_LN881739.1|WP_055640458.1|1838251_1839118_+|hypothetical-protein
MTTALPPRAGRRCHNALNPLHSTLYFSPDLDREFGALGFTDQSAMRLAARSAALGAVGAGTVAATFYNYNHELLSRHLPAVWDIASPADVLAARLRTVDATLRRLLGEDTVSSPEMAEAAMLALRATEACTRHARPLYSAHADLPVPEAPHLAYWYAATLLREHRGDGHLAALLTVGLDPVEALVSHTATGKGMAPRWVLGSRGWKRADWEAATERLRGRGLLDAEGELTEAGTALRDELEERTDLLDSAPYEHLGAAGVERLTELGRGFLVTAAVAGAFPADLVGKG
>NZ_LN881739.1|WP_055640457.1|1837100_1838072_-|GlxA-family-transcriptional-regulator
MTQRSVLVVLFDGVQSLDVTGPFEVFAGAARAAGDPDAYLIRTASLDGGPVRTHSGLRLLPDTTLEEAVAEGPPHTLVVPGGEGTREPDPALLDWLRTHAPRAGRLVSVCTGALLLAEAGLLDGHRATTHWIACDHLARHYPEVDVEPDPIFVRDGRLSTSAGVTAGIDLALALVEEDLGRDVALTVARHLVVFLRRPGNQAQFSVQLAAQTAQREPLRDLQQWITEHPGGDLSVEALAARARLSPRHFARAFQAETGTTPGRYVDLVRLEHARRLLEETSRGVEEVSRTSGYGTPEAMRRAFVKALGTAPAEYRRRFHAVLP
>NZ_LN881739.1|WP_055640456.1|1836298_1836937_-|DJ-1/PfpI-family-protein
MQIAILLYDRFTTLDAVGPYELLARLPGAETVFVAKEAGPVRNDQGSLALVADKSLAEVPSPDIVLVPGGPDARVAMHDPETLDWLRAADATSTWTTSVCTGSLILAAAGLLEGRRATTHWLAFDELRAQGVEPTGERVVFDGKYVTAAGVSSGIDMALHLLGRIAGDEVAQTIQLLTEYDPQPPYDAGSPEKAPAAIVAHWRGEKLPVREG
>NZ_LN881739.1|WP_055640455.1|1835538_1836282_+|enoyl-CoA-hydratase/isomerase-family-protein
MEPQLKDSVTDGIATVVIANPAKRNAMSAAMWRALPGVLDRLAADRTVRALVLTGEGDTFCAGADISTLREPGDEQQSLAVRAEEALAAFPKPTLAAVRGFCVGGGSQLAAACDLRFAEEGARFGITPSKLGIVYPSSSTRRLTALVGPSTAKYLLFSGELMDTERALRTGFVDEVHPAGELDKRVAEFARVLVSRSLLTQAAAKEFADGRADRDAHWAEQARGSGDTAEGVAAFLERRAPRFTYGV
>NZ_LN881739.1|WP_099054349.1|1834698_1835256_-|ATP-binding-protein
MARIEHEGGNRTVDTHGGVPTRSPSYEGVWRFTAPAVDVSVPQARHAVRDLLVRQRVPVHDEIMDGLLLIVSELVTNAVRHAALLSPEIAVEVAIGPEWIRVSVEDNHPYRPKALEADYGQTGGRGLLLVREVAQEAGGACDVEHTASGGKIIWAALPLAPMAPGPGGAPHVPMVTSPRTDPSAP
>NZ_LN881739.1|WP_055640453.1|1834112_1834733_+|isopentenyl-diphosphate-Delta-isomerase
MPTTPATVAQISPEITSNGVQPSGAPAPIMLELVDEDGTTIGTAEKLAAHQAPGQLHRAFSVFLFDESGRLLLQRRALGKYHSPGVWSNTCCGHPYPGEAPFAAAARRTFEELGVSPTLLAEAGTVRYNHPDPASGLVEQEFNHLFVGLVQAEPKPDPEEIEDTAFVTAAELAERHAAAPFSAWFMTVLDAARPAVRELTGPSGGW
>NZ_LN881739.1|WP_055640463.1|1845078_1845540_-|hypothetical-protein
MPSAYTTFDLTRPHRDTSDLVVDGRPLLHRLDEVDGVDAVSPLAADLPPALRADSVRTLLHATGRRIVHSCPDCEDPGCGAVTAVVEHDGEDVVWRDFAWQTGDLADPVDLDRDGYPGVGPYRFRGDTYRSVLLRLLDGATTESHGDARLAAA
>NZ_LN881739.1|WP_055640464.1|1845622_1846579_+|FAD-binding-oxidoreductase
MDSDVIVVGGGVVGLTTAVTLAERGLRVRVWSRDEVTATTSAVAGALWWPYRIEPAAQAGAWALASLRVYGELAADPKRTGVRWVAGVHADTVLDALGPWAKEVPGLRQLAPEEVPGPYGTGLAARLPLIDMPVHLRWLRGRFEASGGVFERRTVTGFAEAAARARVVVDCTGLGARELVPDAGLLPVRGQLVLVENPGVEEWFTAADEGAGETTYFFPQPGRLVLGGTAEEGSERLDADPVTAAAIVARCARVRPEIAGARVLGHRVGLRPARAGGVRIEAVPLPGGGRLVHHYGHGGAGVTVAWGCAERAAELVGG
>NZ_LN881739.1|WP_055640465.1|1846660_1846963_-|hypothetical-protein
MRHTMALRRTLTAVLTTTLLAGGVLLGQTAAAEPAAAARITCNIDKLRSDAHKERTRAAQLRGLGAMAEARKAAARADALERRAQQCHDAENNNRPPLWK
>NZ_LN881739.1|WP_079037336.1|1847081_1848452_-|carboxypeptidase
MRPTNPTDPTSPLNPTSPTTPTRLRTAHRSSRRVLALAAGAAVLTLPLVTVPAKAADSAPPRPLPRTGFETSLGARWTTEAEERDFLAAVDRGSDRVSLRTIGTTSQGRPLRLATLGTGRTTVLLVCSQHGDEPAGREACLSTLRDLSTARDAETSRFLARTTLLVVPTANPDGREADTRGNGDGIDVNRDHLALRTAEARAVAAVIRDRRPELVYDLHEYGATPRYYDKDLLALWPRSLDADPHVHDESRTLSESYVRPAAGLAGYSTGIYGIWTDPLTGKPLKQVAGDGQERILRNTAGIKHAAGLLVETRVDALDEIEKDDPARNHRRRVATQRVALEGMFAYVDERRGPLTAVTAAARLRGFADRGPVFLGGADNDPPEPGEILADPPCGYRLDAAQYAEAGDELALHGVLVRPDGAGVFVPLRQSQRALVPLLLDGRATYHLVSGSPVKEC
>NZ_LN881739.1|WP_055645922.1|1848457_1850494_-|Xaa-Pro-dipeptidyl-peptidase
MRKRRTRGARLPYGTLVAAATAALLATLVTPAGASPEPSAPTALTAPSAGSPRESRPVHSYADAIRESVWVDTGLDGDADGRTDRVAVDIIRPREPAAAGRKIPVIMDASPYYACCGRGNESQKKTYDADGNPVQFPLFYDNYFVPRGYAFVGVDLAGTNRSDGCDDVGGRSDVRSAKAVVDWLNGRARGYTTRTGTTRAGATGWSTGNVGMIGKSWDGTVANGVAATGVEGLKTIVPIGAISSWYDYFHSQGAPLYNANPSWLSDYVSSPDARARCGAVQERIAAATPYSGDWTPAWSERDHVRDASKVKASVFVVHGQQDLNVRAKQFGQWWDALAAQGVERKIWLSQTGHVDPFDFRRADWVRTLHRWFDHYLLGYDNGIDREPVADIERAPDRWTTDRQWPPRGTAATTLRPAAGTEPGVGTLGRTPAATGSTATFTDDPALGELDWAARVDSPTPEKAGFVTRPLSRDLRISGSSKVTVTATPTTATAHLSAVLVDLGPDTIRDYGAVGEGITTLADRSCWGASTPGDSACFKETRANTADVGYTVVSRGWADLGTWADPREERPLTPGRAYTLTLDLASADHVVPAGHRLALIVGGTDRDLIDPPSTTPTLTLDLGRTSAKLPLVGGPAAFARATTGPAPALPAPAARPSLTGPVPPAAVGGPRLPASGAAR
>NZ_LN881739.1|WP_055640467.1|1850713_1852285_+|M1-family-metallopeptidase
MHRRIIVPSALAASLLLAIPASAADFAPGAPGIGDSYYPASGNGGYDVSHYDLRLKYQPETDLLEGTATIVATTKQNLSRFNLDLGLKVSEVRVNGRLAKFATSGDHELEVTPAVPLEKNKAISVVVRYAGKPSEFKVDGWSAWARTPDGGVAAQEPDSAVWWFPSNDHPLDKATFDVSVSVPDGTQAISNGVLQSQSSRLGWTRFNWRSNKPQATYLATLAVGKFDITTDKTANGLPVLNAYSKDLGDNAGAARASIERTTEVAEWLEGVFGPYPFNSLGGYVPNVTSGFALETQTRPFYSPRQFANGANVSVVVHELAHQWYGDSVSVRDWKDIWVNEGFARYSQWLWSEKEGEGTAQELADYVYATRTAEDPFWTVKPGDPGAENQFHIAVYDRGALALQALRNEIGDEDFFAILKGWPQEFAYGNARVGDFVRYAERVSGKPLAGLFDTWLYQPSKPAASTAAAAGLSAPKAAAPASGPAARSAARSAAPKPVQPKSWKKIAATNTVHDHDEHEGHGKH
>NZ_LN881739.1|WP_055640468.1|1852304_1853189_-|DUF2236-domain-containing-protein
MSHPQQPAARTPAGDPAPPPVGGVLWSIAGDIRALLMLPAALTMQVAHPAIGAGVDEHSVFRTDPWGRGERSLRSVQLWVYGGEAAAEEGRRLRRLHRDIQGTDAHGRTYHALTPAYYSWVHATGFPVYRYGLGLLARPLTDAQERQLYAEWLQVGRVLGIHDRDMPQTIDEFWPYYRKVLADELEATVVVRELLDPDLPVPAPDRGPLPLRLALRLVWPALRRPFLRLRAFLTVGLMPPDAREAIGLEWTDAQERTLRRFARVVRAVVPVLPERLRYLPLARTAREAARRAKR
>NZ_LN881739.1|WP_055640469.1|1853330_1853819_-|ATP-synthase-F0-subunit-B
MTLASNPTVFEMDLGPLNPVWAELILGVVLFALTFLILAKGILPKIRRTLDEREDAIDGGTERADDLRSEATQIREQYEAELAEARHEAARIRSAAIEEGSAAIAAARAEGSAERDAIISAGAAKIATERAAAERELTADVDAWAHALAARIVGEPVGADRS
>NZ_LN881739.1|WP_055640470.1|1853977_1854979_+|sphingomyelin-phosphodiesterase
MGVPVSFAVLRRAPGAALSLALAAATLAATAPAAGAASAATAETPRLKVLSYNTFLFSKALYPNWGQDHRAKAIPAASFFQGQDVVVIQEAFDNSSSDALKANAAAQYPHQTPVMGRSKTGWDATGGSYSATTPEDGGVTILSKWPIVRKEQYVYKDACGADWYSNKGFVYTVLDVNGSRVHVVGTHAQSTDPGCSAGEAAQMRSRQFKAMDAFLDAKNIPANEQVIVAGDMNVDSRTPEYGTMLADAGLVGADARTGHTYSFDTDVNSIASERYPDDPREDLDYVLHRAGNARPAGWTNHVVLEESAPWTVSSWGTRYTYTNLSDHYPVTAF
>NZ_LN881739.1|WP_055640471.1|1855007_1855493_-|hypothetical-protein
MYVQLRETADELARVLWREHTVYRERGGGVVIRGEHVRRWISLAPTGGKDRALLRAGRILDGGTTAPARSEIVVDLTSGTAELATICRRLLADVAAGADAAPGPSRAGRPKEKAGKPGKQAKPGRRPRGSRHTSPGSWFVLLCVAAVLGAWLYSLFGRAGY

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Crispr_ID: NZ_LN881739_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN881739_4

4530568-4530668

Orphan

Consensus_repeat	Method
TGTTTCACGTGAAACATCACCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LN881739_4

>merge|NZ_LN881739|4|4530568-4530668|CRISPRCasFinder
TGTTTCACGTGAAACATCACCCCTCCACCGCCTCGCCGCCATGGTCTCGATCGCGCGGATGTTTCACGTGAAACGCGGTGTTTCACGTGAAACATCACTCC

>NZ_LN881739|4|4|4530568-4530668|CRISPRCasFinder
TGTTTCACGTGAAACATCACCCC	TCCACCGCCTCGCCGCCATGGTCTCGATCGCGCGGATGTTTCACGTGAAACGCGG
TGTTTCACGTGAAACATCACTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN881739.1\|WP_079037920.1\|4532317_4534678_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055642440.1\|4524236_4526633_-\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NZ_LN881739.1\|WP_055642447.1\|4539489_4540428_+\|zf-HC2-domain-containing-protein	unknown	unknown	gnl\|CDD\|379219
NZ_LN881739.1\|WP_055642438.1\|4521541_4522573_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_LN881739.1\|WP_055642445.1\|4534723_4536955_+\|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl\|CDD\|273763
NZ_LN881739.1\|WP_055646155.1\|4538800_4539493_+\|RNA-polymerase-sigma-factor-SigM	unknown	unknown	gnl\|CDD\|236604
NZ_LN881739.1\|WP_055642435.1\|4518641_4519232_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|236092
NZ_LN881739.1\|WP_055642439.1\|4522588_4524115_-\|DUF2029-domain-containing-protein	unknown	unknown	gnl\|CDD\|227937
NZ_LN881739.1\|WP_055642436.1\|4519880_4520198_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055642446.1\|4537071_4538763_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270875
NZ_LN881739.1\|WP_055642450.1\|4541996_4542614_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_LN881739.1\|WP_055642444.1\|4530685_4532128_-\|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|131739
NZ_LN881739.1\|WP_055642449.1\|4541582_4541915_+\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
NZ_LN881739.1\|WP_055642443.1\|4529307_4530567_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_LN881739.1\|WP_055642448.1\|4540567_4541533_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_LN881739.1\|WP_055642442.1\|4528151_4529234_+\|inositol-3-phosphate-synthase	unknown	unknown	gnl\|CDD\|132491
NZ_LN881739.1\|WP_005482942.1\|4519305_4519596_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|179034
NZ_LN881739.1\|WP_055642437.1\|4520340_4521459_+\|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein	unknown	unknown	gnl\|CDD\|225224
NZ_LN881739.1\|WP_055642451.1\|4542775_4543873_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NZ_LN881739.1\|WP_055642441.1\|4527420_4528101_+\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609

Protein	Function_ID	Function_description	E-value
NZ_LN881739.1\|WP_055642440.1\|4524236_4526633_-\|penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	6.10619e-147
NZ_LN881739.1\|WP_055642447.1\|4539489_4540428_+\|zf-HC2-domain-containing-protein	gnl\|CDD\|379219	pfam13490, zf-HC2, Putative zinc-finger. This is a putative zinc-finger found in some anti-sigma factor proteins.	0.00194355
NZ_LN881739.1\|WP_055642438.1\|4521541_4522573_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	1.36577e-09
NZ_LN881739.1\|WP_055642445.1\|4534723_4536955_+\|murein-biosynthesis-integral-membrane-protein-MurJ	gnl\|CDD\|273763	TIGR01695, Putative_lipid_II_flippase_MurJ, murein biosynthesis integral membrane protein MurJ. This model represents MurJ (previously MviN), a family of integral membrane proteins predicted to have ten or more transmembrane regions. Members have been suggested to act as a lipid II flippase, translocated a precursor of murein. However, it appears FtsW has that activity. Flippase activity for MurJ has not been shown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	7.41962e-150
NZ_LN881739.1\|WP_055646155.1\|4538800_4539493_+\|RNA-polymerase-sigma-factor-SigM	gnl\|CDD\|236604	PRK09643, PRK09643, RNA polymerase sigma factor SigM; Reviewed.	2.34913e-92
NZ_LN881739.1\|WP_055642435.1\|4518641_4519232_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	3.63028e-90
NZ_LN881739.1\|WP_055642439.1\|4522588_4524115_-\|DUF2029-domain-containing-protein	gnl\|CDD\|227937	COG5650, COG5650, Predicted integral membrane protein [Function unknown].	1.15804e-37
NZ_LN881739.1\|WP_055642446.1\|4537071_4538763_+\|serine/threonine-protein-kinase	gnl\|CDD\|270875	cd13973, PK_MviN-like, Pseudokinase domain of the peptidoglycan biosynthetic protein MviN. The pseudokinase domain shows similarity to protein kinases but lacks crucial residues for catalytic activity. This family is composed of the mycobacterial protein MviN and similar proteins. MviN is an integral membrane protein that is essential for growth and is required for cell wall integrity and peptidogylcan (PG) biosynthesis. It comprises of 14 predicted transmembrane (TM) helices at the N-terminus, followed by an intracellular pseudokinase domain linked through a single TM helix to a carbohydrate binding extracellular domain. Phosphorylation of the MviN pseudokinase domain by the PG-sensitive serine/threonine protein kinase PknB recruits a forkhead associated (FHA) domain protein FhaA, which modulates local PG synthesis at cell poles and the septum. The MviN pseudokinase forms a canonical receptor kinase dimer.	8.59885e-58
NZ_LN881739.1\|WP_055642450.1\|4541996_4542614_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.000210216
NZ_LN881739.1\|WP_055642444.1\|4530685_4532128_-\|CCA-tRNA-nucleotidyltransferase	gnl\|CDD\|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	0
NZ_LN881739.1\|WP_055642449.1\|4541582_4541915_+\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	1.2261e-45
NZ_LN881739.1\|WP_055642443.1\|4529307_4530567_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.77608e-43
NZ_LN881739.1\|WP_055642448.1\|4540567_4541533_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	1.1787e-155
NZ_LN881739.1\|WP_055642442.1\|4528151_4529234_+\|inositol-3-phosphate-synthase	gnl\|CDD\|132491	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type. This enzyme, inositol 1-phosphate synthase as found in Actinobacteria, produces an essential precursor for several different products, including mycothiol, which is a glutathione analog, and phosphatidylinositol, which is a phospholipid.	0
NZ_LN881739.1\|WP_005482942.1\|4519305_4519596_-\|30S-ribosomal-protein-S6	gnl\|CDD\|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	8.20181e-40
NZ_LN881739.1\|WP_055642437.1\|4520340_4521459_+\|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.43762e-34
NZ_LN881739.1\|WP_055642451.1\|4542775_4543873_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.06972e-79
NZ_LN881739.1\|WP_055642441.1\|4527420_4528101_+\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	8.13039e-18

>NZ_LN881739.1|WP_055642443.1|4529307_4530567_+|MFS-transporter
MSVVRDLRVLLRLTNFRRLLAVRLLSQGADGVYQVALATYVVFSPEKQTSATAIASAMAVLLLPYSLVGPFAGVFLDRWQRRQVFLYGNLLRALLACGTAVLIVASVPDWLFYASALSVTAVNRFVLAGLSAALPRVVDEERLVVANSLSPTAGTLAATLGGGLAFGVRLLTDESDAAVVAFGAALYLLSALASLRIPRGLLGPDQELAPQRIASALASTARGLVEGVRHLAERRPAARALTAVALMRFCYGALLVTVLMLSRYAWSTTESEGLGLLGIAVAASGAGFFAAAVISPWAVGRLGPFGWMTLCAGIAAVLEPMLGLFFDPVPFLVAVFVLGLITQGAKIATDTVVQTNVDDAYRGRVFSLYDVLFNVAFVAAAGIAALMLPPDGRSPLLVVLVAVLYAAIALALRKERVEG
>NZ_LN881739.1|WP_055642442.1|4528151_4529234_+|inositol-3-phosphate-synthase
MGSVRVAIVGVGNCAASLVQGVEYYKDADPAAKVPGLMHVQFGDYHVGDVEFVAAFDVDAKKVGLDLSDAIGASENNTIKICDVPNAGVTVQRGHTLDGLGKYYRMTIEESAEEPVDVVQILKDRQVDVLVCYLPVGSEDAAKFYAQCAIDAKVAFVNALPVFIAGTKEWADKFTEAGVPIVGDDIKSQVGATITHRVMAKLFEDRGVRLERTMQLNVGGNMDFKNMLERDRLESKKISKTQAVTSQIPDRELGEKNVHIGPSDYVAWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGVIIDALRAAKIAKDRGIGGPILSASSYFMKSPPVQYFDDEALANVEKFIKGEVER
>NZ_LN881739.1|WP_055642441.1|4527420_4528101_+|PadR-family-transcriptional-regulator
MSRRSGILEFAVLGLLREAPMHGYELRKRLNTSLGVFRAFSYGTLYPCLKTLVANGWLIEEPGSAPEEALAASLAGRRAKIVYRLTPEGKEHFEELLTHTGPDAWEDEHFAARFAFFGQTEREVRMRVLEGRRSRLEERLEKMRASLARTRERLDDYTLELQRHGMESVEREVRWLNELIESERAGRDQRSGPGAPALHDNDSGETGGLPRHGGSTRPDPSDDTAK
>NZ_LN881739.1|WP_055642440.1|4524236_4526633_-|penicillin-binding-protein
MPSWKLVTGTFLVFVGVLMGGAVFAYSKVTIPETDETAVSQNNIYYWSDGTRMVATGSGTNRQIVGIEQIPRVMQEAVVSAENKTFWDDSGIDPMGMGRAVWNMAKGGETQGGSTITQQYVKNNRLNDQSQTLTRKVKELFISMKVGNDVGKPEIMAGYLNTSYYGRGAYGIQAASRAYFNKDAKHLNASESALLTAVLKGATYYDPAGYPEIDPEATPDKNLDRATKRWSWILDEMVKDGKITAEERNKYTTFPKVQKRKQDAQLSGQIGYLVSTAKANFINNNTDGIGAKELERGGYEIYTTFEKKKVNDLEAAVKKVYDENIDPKKRPKTDTNVQFGGASVNAQTGALVAIYGGADATKHFTNNADTTGAQVGSTFKPFVLAAAMQDGVRDKDLGRLQDASSRTIVDPDKSRYSGKNKLKIRQYNGEIWENEKGEEWFQTNDGDASYGPMTLRRAMIKSANSPYVQLGMDVGIDKVREAAVKAGLREDSLVKGEVPSFSLGISSPSAIRMAGAYATFADNGQQKDPFSVTKVVKNGKTIYKHEAKTVQAFSTAIASNVTDVLRSVVEDPEGTGRKAAIPGRAVAGKTGTTDGNKSAWFVGYTPQLSTAIDMYRFDDDETKKNREFEEMYGTGDRDTIHGSSFPSQIWNDYMTDAVADMPDVKFPEPEDLENAEPVFGGGATSPTPSPTATPTPTETTATPTTEAPTTTPPATPTTTPPTRPTKSPKPGKTTCSVWDFDCNNPGGDPGGNTGEPTTTPPTTTEAPTPTDSATTEDPGDETGRPGGGGNGGNAAWTP
>NZ_LN881739.1|WP_055642439.1|4522588_4524115_-|DUF2029-domain-containing-protein
MPSLQKTREPQDRPQGPRTVIPTHRDEVAAAGSELIGGPFGRRALTGRGQFTPVRVIALVAIGMFALGMVQKLPCYNWAWFRGTTSQYTHACYSDIPHLFSGRGFADGLVPYFDRLTGDIPFLEYPVLTGLFMEVAAWLTPGSGTMDHREQTFWMVNAGMLMVCAAVLAVCVTRTHRSRPWDGLLVALAPSIALTATINWDILAVALTSAAVLLWSRGRPLGFGILLGLATAAKFYPILLLVPLLLLCWRAGKWREYGTAVLGAAGAWLVVNLPVMLMAPEGWKQFYLFSRDRNVDFGSVWLLVSQRTGTSITPDKANMYALMLMVVAVVALGFLAFSAPRRPRFAQLAFLVVAAFVLTNKVYSPQYVLWLVPLAALARPRWRDFLIWQACEVMYFLGIWMYLAFMNSGNKQGLPVDGYQFAIVLHLLGTLYLCVMVVRDILLPEKDPVRQDGSDDPSGGVLDGAEDVFVTGRAAHPARHAAPAAEGPRVEWGTPGDPEPVTERDSRG
>NZ_LN881739.1|WP_055642438.1|4521541_4522573_+|alanine-racemase
MALSLYVDTARWRAHQKTVIDQFPGLIPVCKGNGYGFGHERLADEAARFGADMLAVGTTYEAAKIKDWFSGDLLVLTPFRRGEEPVPLPDRVIRSVSSVDGVHALVGARVVIECMSSMKRHGVHEGELQQLHAAIEDVRLEGFALHLPLDRPDGTDAVEEVIAWMDRLRAARLPLHTMFVSHLRAEEQARLQQQFPQTRFRARIGTRLWLGDHEATEYRGAVLDVTRVAKGDRFGYRQQKAASDGWLVVVAGGTSHGVGLEAPKAMHGVMPRAKGVARAGLATVNRNLSPFVWAGKQRWFAEPPHMQVSILFVPSDAQEPRVGDELVAHLRHTTTQFDRLVER
>NZ_LN881739.1|WP_055642437.1|4520340_4521459_+|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein
MSLTLRTISREQHLGFIQSQPAASHCQVPAWADVKTEWRSENLGWFDKNGELVGVGLVLYRQLPKIKRYLAYLPEGPVINWHAPNLDDWLQPMLAHLKQQGAFSVKMGPPVVIRRWDAAAIKSGIQDPDVKRLKDVEATHIEPRAFEVADRLRKMGWQQAEDGGAGFGDVQPRYVFQVPLANRSLDDVLKGFNQLWRRNIKKAEKAGVEVVQGGYEDLAEWQRLYEITAVRDHFRPRPLSYFQRMWTVLNNEDPNRMRLYFARHNGVNLSAATMLVVGGHVWYSYGASDNIGREVRPSNAMQWRMLRDAYAMGATVYDLRGISDSLDETDHLFGLIQFKVGTGGEAVEYVGEWDFPLNKLLHKALDIYMSRR
>NZ_LN881739.1|WP_055642436.1|4519880_4520198_+|hypothetical-protein
MAQAMRPDPGHSLFATDGKPHPLQDTLVGVTLILGVLAFVTAQFDNLHLLSSWSGLIGILTGAYGQFISVTTRERFLLVVGLGASAFGFYLGMAHGGLFGGVISY
>NZ_LN881739.1|WP_005482942.1|4519305_4519596_-|30S-ribosomal-protein-S6
MRHYEVMVILDPDLEERAVAPLIENFLSVVREGNGKVEKVDTWGRRRLSYEIKKKPEGIYSVIDLQAEPAVVKELDRQMNLNESVLRTKVLRPETH
>NZ_LN881739.1|WP_055642435.1|4518641_4519232_-|single-stranded-DNA-binding-protein
MAGETVITVVGNLVDDPELRFTPSGAAVAKFRIASTPRTFDRQTNEWKDGESLFLTCSVWRQAAENVAESLQRGMRVVVQGRLKQRSYEDREGVKRTVYELDVEEVGPSLKNATAKVTKTTGRGGQGGYGGGGQQQGGGSWGGNSGGGAPQGGGGAPADDPWATGAPSGGSGAQQGGGGGGWGGNSGGGYSDEPPF
>NZ_LN881739.1|WP_055642444.1|4530685_4532128_-|CCA-tRNA-nucleotidyltransferase
MPNANEDTPTALSQVQRRAVSELLRVSPVADDLARRFQEAGFSLALVGGSVRDALLGRLGNDLDFTTDARPEDVLKIVRPWADSVWEVGIAFGTVGSQKDGYQIEVTTYRSEAYDRTSRKPEVSYGDSIDQDLVRRDFTVNAMAVALPEKEFIDPYGGLEDLAARVLRTPGTPEESFSDDPLRMMRAARFAAQLDFEVAPEVVTAMREMSGRIEIVSAERVREELNKLLVSAHPRKGLGLLVDTGLADHVIPELPALRLESDEHHRHKDVYEHSLTVLDQAIDLEEDGPDLVLRLAALLHDIGKPRTRRFEKDGRVSFHHHEVVGAKMTKKRMTALKYSNEMIKDVSRLVELHLRFHGYGDGEWTDSAVRRYVRDAGPLLSRLHKLTRSDCTTRNKRKATALSRTYDGLEERIAQLQEQEELDAIRPDLDGNQIQEILGIGPGPAIGQAYKFLLELRLENGPMEHDQAIAALKEWWAARG
>NZ_LN881739.1|WP_079037920.1|4532317_4534678_+|hypothetical-protein
MGEAADIQGTGPSPARRWLRRTITVAVGAPLLAGLLQAPTATPADAAAEAAVSKTVDVSLDTLSPVAPVEGDTVTVSGTVTNRGKKTITDATVNLRVGPMMTSRSEIDQVSDRTGYRGDSDPAPLDEAPTVKIARLGAGLSADFSLTVPVSELGLDESGVYQLGVSLTGQTSSQRYDRVLGIERTFLPYQPEATEKKTQLTYLWPLISSAHVSAETATDDQQTPVFEDDALAAELRPGGRLEQMVSLGKDLPVTWVIDPDLLATVDAMANGYRVKDGTAHVPGKNKAVAEQWLNALEKAVQGRKIVALPFADPDLASLAHRGKDVPGSLGHLQSATSLAETTVETVLHVQPSTDFAWPVEGAVDPSIVAVATSAGANKVIARSDSVRDDLSYTPTAARPLGNGSTTAVVSDKLLSTAFEGDMVRTENSTLAVQEFLAQSLAITLEQPEQQRSVVVAPQRVPSVSQAQTMATALRGLSAQRWSHPIDLQAAAVAKPDPDASTTVPSGSRYPKKLRDRELPVQTFRDMKTTRDELDDFKIVLTLPDRVVTPFGNAINREMSTSWRGQARSAAVYRNDVLQYLQDLTEGIQLVDKSDLTLSGRSATIPVTVQNKLLQGVDDLVLRLTSGNGNRLELNGGRYAELPVKINAGHSQSVKFEASANVNGQVPMTAQLYTADGTPYGQPMTFNVKVSEITATVMLVIAGGVLLLVLAGVRMYSQRKRVAARKAETDVAEPETEESEPGTETDPGDGGDGEDVEDGEPEQPSDPTPDTGFESGDPSGPGEKVDR
>NZ_LN881739.1|WP_055642445.1|4534723_4536955_+|murein-biosynthesis-integral-membrane-protein-MurJ
MNAPYDGDRGQGAGGTAPSGGTPAAPPGSGYPPVPPSAQQGVPDPHGQDPYAQNPYAQDPYVQDAFTHDPYRAQDLSAQDPVTEALYDRAAHPPPPPGTYQEPQPLYQQPAAPQHAPDPRVWAQTPAPEPDGPSRHLPYGDDARTVQFTGVDDLVTRAGEEQPEPDAFAHLYRDQQTPGQVPPPASDPDPMPVPAPAPKKSGRASGLLKSSAVMAAGTLVSRLTGFVRSLVITGALGAALLGDTFTIAYTLPTMIYILTVGGGLNSVFVPQLVRSMKNDEDGGEAYANRLLTLVMVALGLIVVAAVLAAPVLVRLMSNTIADDAAANSVAVTFARYCLPTIFFMGVHVVMGQILNARGKFGAMMWTPVLNNIVMIVTFGLFIWVYGTSAESQMGVQTIPDEGIRLLGIGTLLGLVVQALAMIPYLRETGFRFRPRFDWKGHGLGKTVKLAKWTVLFVLANQAGVLVVTQLATAAGQESGKNGAGFLAYSNAQLIWGMPQAIITVSVMAALLPRISRAAHDNDPGAVRDDISQGLRNSAVAIVPVSFAFLALGVPMCTLLYASSGVEAAQGMGFILMAFGLGLIPYSVQYVVLRGFYAYEDTRTPFYNTVIVAAVNAAASALCYVLLPAQWAVVGMAGAYGLAYAVGVGIAWRRLSKRLGGDLDGTQVLRTYARLCMASVPAAIVAGAVGFGLLKLLGEGALGSLVALLVGGAVLLGVFFLAAKRMRITELNTLVGMVRGRLGR
>NZ_LN881739.1|WP_055642446.1|4537071_4538763_+|serine/threonine-protein-kinase
MAERSTAAVDVADSGDDPLTAKADKAATDGVATTQKMAEKSAEPTGSKAVERQSGEQPSITAPELHSGHKLARRYRLEECVTRLDGFSSWRAVDEKLRRAVGVHLLPADHPRARSVLAAARSAALLGDPRFVQVLDAVEENDLVYVVHEWLPDSTELTALLATGPMEAHDAYQLVSQVSQAMAAAHREGLAHLRLTPSAVLRSSTGQYRIRGLAVNAALRGITAERPQRTDTEAIGALLYAALTQRWPYDSDAYGLSGLPKGVGLLSPDQVRAGVHRGLAEIAMRALANDGATASRQDRPCTTPDELAKAVAAMPRVKPPEPTFATPPDYQRTTYQQGTYGRPQARPVAAPQPVIPPPAPLQSRTGTALKWAVSALLIAALGLGSWQIADRLLAPESTTKSPVPTPTVDEKPEPPKPISIASAQDFDPPPKGSGGENPQAIQLAYDGDPNTYWHTVNYFGSDFANLKPGVGMVLDLGTAKEISSVELSFVGQTSVELRTAPSDASSAPSTADEFTTQAEGSGSNVTLKPTKPITTRYVLVWLTELPANDGGFRGKLSEIKILG
>NZ_LN881739.1|WP_055646155.1|4538800_4539493_+|RNA-polymerase-sigma-factor-SigM
MDESTGDQELLARHVAGDPDAFSELVRRHRDRLWAVALRTLGDREEAADALQDALLSAFRAAHTFRGQSAVTTWLHRITVNACLDRARKAASRRTSPVDDTNRFEQLLDPHESAEAPAERQDLHRQVLAALALIPEDQRAALVLVDMQGYPVAEAARILGVPTGTVKSRCARGRSRLLPMVTHLRADTVGNEATEGGRNRTPGTSVPPVPGPTNTGPTDPAAVKGGGGRA
>NZ_LN881739.1|WP_055642447.1|4539489_4540428_+|zf-HC2-domain-containing-protein
MTSTTGKADTTQHPDVSEISDLTEGLLSPSRSAAVRRHLDGCPLCADVRTSLEEIRGLLGTLPGPPRMPAEIAGRIDAALAAEALLQATAPESGTPVSRETSRPRTEPLASGAPSPATERPAGRPSAATGPGRPGKPRRRRIALASTIGTAFAAAVLGTTLLLSQGGGPTAGIADGAKKADAGAVAMSSFSGTPVEERVHALLGEAPGTAKTPQGIGPESMSAESTAATPQRNRDSAAVPGCVLAGTGRTDAVLAQERGEYEGTPAYLLVLADPADSTRVQAFVLDASCADRPTNTGSPAADLLLSETYPRS
>NZ_LN881739.1|WP_055642448.1|4540567_4541533_+|thioredoxin-disulfide-reductase
MSDVRNVIIIGSGPAGYTAALYTARASLNPLVFEGAVTAGGALMNTTEVENFPGFRDGIMGPDLMDNMRAQAERFGAELVPDDIIAVDLTGDIKTVTDTAGTVHRAKAVIVTTGSQHRKLGLPNEDALSGRGVSWCATCDGFFFKDQDIAVVGGGDTAIEEATFLSRFAKSVTIVHRRDTLRASKAMQERAFADPKISFAWDSEVTAIHGEQKLSGLTLRDTKTGATRELAVTGLFIAVGHDPRTELFKGQLELDDEGYLKVAAPSTRTNLTGVFGAGDVVDHTYRQAITAAGTGCSAALDAERFLAALADSEKLAETPAV
>NZ_LN881739.1|WP_055642449.1|4541582_4541915_+|thioredoxin
MALKNVTDASFDEDVLKSGKPVLVDFWAAWCGPCRQIAPSLEAIAAEHGEIEVVKLNIDENPATAAKYGVMSIPTLNVYQGGEVVKTIVGAKPKAAILRDLADFVTPANG
>NZ_LN881739.1|WP_055642450.1|4541996_4542614_-|GNAT-family-N-acetyltransferase
MGRRLVPLTLDNLPDLPRRCRSCVFWELDPVSGEAAVKAGRPETEKEAWISAVLLEWGSCGRVVYVDEVPVGYVLYAPPAYVPRSTAFPTSPVAADSVQLMTAWIMPGYQGQGLGRMIVQTVAKDVMRRGFKAIEAFGDARWKEPACVLPADHLLAVGFKTVRPHHAFPRLRLELRTTLSWKEDVEMALDRLLGAVQKEPALRPL
>NZ_LN881739.1|WP_055642451.1|4542775_4543873_-|ParB/RepB/Spo0J-family-partition-protein
MSKRPRGLGRGLGALIPAAPQEQKVPAVGLGVGASSPGAVPGLPSERGVAAAKLATLPHSSPSPDSDTSWGEAVEVALPEVQGGAYFTELPIEAIVPNRHQPREVFDEDALAELVISIKEVGLLQPVVVRKLGDERYELVMGERRLRASTTAGLERIPAIVRDTDDEKMLLDALLENLHRAQLNAIEEAHAYEQLLKDFGCTHDQLAERIGRSRPQISNTLRLLRLSPPVQRRVAAGVLSAGHARALLGVEDAEAQDQLAYRIVAEGLSVRTVEEIVSLMGSEEPAAVKPKGPRAGGRVSPALTDLASRLSDRFETRVKVDLGQKKGKIVVEFASMDDLDRILSTLAPGEGKVMDQKNAQQSEQG

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Crispr_ID: NZ_LN881739_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN881739_5

4843868-4843970

Orphan

Consensus_repeat	Method
GACCGGTCCGTCGCGGCGGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LN881739_5

>merge|NZ_LN881739|5|4843868-4843970|CRISPRCasFinder
GACCGGTCCGTCGCGGCGGGCGGCGACATCGGGAGCGTGTCCACGGGCGACGCGTGAGCGGGGGCGTATCCGCCTCGGGGGACCGGTCCGTCGCGGCCGGCGG

>NZ_LN881739|5|5|4843868-4843970|CRISPRCasFinder
GACCGGTCCGTCGCGGCGGGCGG	CGACATCGGGAGCGTGTCCACGGGCGACGCGTGAGCGGGGGCGTATCCGCCTCGGGG
GACCGGTCCGTCGCGGCCGGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN881739.1\|WP_055642660.1\|4834289_4834763_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_LN881739.1\|WP_079037531.1\|4848570_4849299_+\|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|132028
NZ_LN881739.1\|WP_055642674.1\|4854562_4855594_-\|AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_LN881739.1\|WP_055642663.1\|4836980_4837688_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_LN881739.1\|WP_024760130.1\|4845970_4847242_+\|aspartate-kinase	unknown	unknown	gnl\|CDD\|235843
NZ_LN881739.1\|WP_055642675.1\|4855906_4857304_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055642672.1\|4853374_4854205_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_LN881739.1\|WP_055642662.1\|4835531_4836896_+\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|235687
NZ_LN881739.1\|WP_055642669.1\|4847238_4848306_+\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_LN881739.1\|WP_017240166.1\|4840099_4840699_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_LN881739.1\|WP_079037530.1\|4839683_4840019_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_LN881739.1\|WP_055642671.1\|4850703_4851444_-\|SURF1-family-protein	unknown	unknown	gnl\|CDD\|376731
NZ_LN881739.1\|WP_055642670.1\|4849295_4850561_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368370
NZ_LN881739.1\|WP_055642673.1\|4854201_4854513_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_079037529.1\|4838690_4839431_-\|SLATT-domain-containing-protein	unknown	unknown	gnl\|CDD\|375613
NZ_LN881739.1\|WP_055646192.1\|4851467_4853303_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NZ_LN881739.1\|WP_055642666.1\|4840743_4841403_+\|DUF5063-domain-containing-protein	unknown	unknown	gnl\|CDD\|374737
NZ_LN881739.1\|WP_055642664.1\|4837881_4838532_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055642667.1\|4841438_4843430_+\|tetratricopeptide-repeat-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055642661.1\|4834759_4835365_-\|thiamine-biosynthesis-protein-ThiJ	unknown	unknown	gnl\|CDD\|153234

Protein	Function_ID	Function_description	E-value
NZ_LN881739.1\|WP_055642660.1\|4834289_4834763_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.10248e-11
NZ_LN881739.1\|WP_079037531.1\|4848570_4849299_+\|SigE-family-RNA-polymerase-sigma-factor	gnl\|CDD\|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	2.29326e-53
NZ_LN881739.1\|WP_017240166.1\|4840099_4840699_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	1.07483e-123
NZ_LN881739.1\|WP_055642663.1\|4836980_4837688_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	8.31615e-27
NZ_LN881739.1\|WP_024760130.1\|4845970_4847242_+\|aspartate-kinase	gnl\|CDD\|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
NZ_LN881739.1\|WP_055642672.1\|4853374_4854205_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.01349e-11
NZ_LN881739.1\|WP_055642662.1\|4835531_4836896_+\|aspartate-aminotransferase-family-protein	gnl\|CDD\|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
NZ_LN881739.1\|WP_055642669.1\|4847238_4848306_+\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	1.19725e-116
NZ_LN881739.1\|WP_079037530.1\|4839683_4840019_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	4.79465e-36
NZ_LN881739.1\|WP_055646192.1\|4851467_4853303_-\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	9.4949e-49
NZ_LN881739.1\|WP_055642670.1\|4849295_4850561_+\|hypothetical-protein	gnl\|CDD\|368370	pfam05283, MGC-24, Multi-glycosylated core protein 24 (MGC-24), sialomucin. This family consists of several MGC-24 (or Cd164 antigen) proteins from eukaryotic organisms. MGC-24/CD164 is a sialomucin expressed in many normal and cancerous tissues. In humans, soluble and transmembrane forms of MGC-24 are produced by alternative splicing.	0.000184007
NZ_LN881739.1\|WP_055642674.1\|4854562_4855594_-\|AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	6.00313e-15
NZ_LN881739.1\|WP_079037529.1\|4838690_4839431_-\|SLATT-domain-containing-protein	gnl\|CDD\|375613	pfam18183, SLATT_2, SMODS and SLOG-associating 2TM effector domain 2. The SLATT domain contains two transmembrane helices. SLATT domains are generally predicted to function as pore-forming effectors in a class of conflict systems which are reliant on the production of second messenger nucleotide or nucleotide derivatives. SLATT domains are predicted to initiate cell suicide responses upon their activation. This SLATT family is the only prokaryotic SLATT family to exist as a standalone domain, with no as-yet discernable genome associations.	3.52449e-124
NZ_LN881739.1\|WP_055642666.1\|4840743_4841403_+\|DUF5063-domain-containing-protein	gnl\|CDD\|374737	pfam16702, DUF5063, Domain of unknown function (DUF5063).	1.09318e-49
NZ_LN881739.1\|WP_055642671.1\|4850703_4851444_-\|SURF1-family-protein	gnl\|CDD\|376731	pfam02104, SURF1, SURF1 family.	3.11176e-31
NZ_LN881739.1\|WP_055642661.1\|4834759_4835365_-\|thiamine-biosynthesis-protein-ThiJ	gnl\|CDD\|153234	cd03140, GATase1_PfpI_3, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	9.5019e-60

>NZ_LN881739.1|WP_055642667.1|4841438_4843430_+|tetratricopeptide-repeat-protein
MTGGAGRADASGDRSVAAGGAIGRVNTGDFVTQVENATLLPPEALTVSPAGLVHLPERTQLFVGRARELALLDEGMGIQVLCGLGGIGKSTLAARWAADRVADHSVVWWITAETPAELDAGLADLARAMQPGVVGVLPEDALRERALQWLATNDDWLLVLDNVSAPADLHPLLARVGSGRIVVTSRRASGWQDIARTVVLDVLGPEEAAELFRGRRVGSGDGLELLCAELGYLPLALKQAAAYCAEAGITPRTYLGLLAKHPAEMFAATEEGGEAARTLARVWQVTLERLSDTPLAVGVLRIIAWWAPEEIPRRFLEPLGTALGVTEAVRRLAAHSMITLRDGELNVHRLVQAVVRADPSEETESAREKATGLLNECAPKDESHADRQIAVHAEALAGHTDPTDDTEDAAILFLIASGIFGMVMSMSRAASLSGRGADALRRIHGPDHPAVLWAVQTCALHRHMAGGGSEAAAELLTTGLADGLRVLGPDDPQTLSARRNLAVVLRSIEPERAVELFHENVEHCHRVLGARHPQTIAARYDLIEASSDADVRALEELLSDAERASPEDPFLCETIQRHLILLVAGTGETKRALAIAAEGVESCRRRYGDADSRTLVSRLIEVEVLREDGQMQRARALAIALEEDSLRVLGEGQLTELARVMQS
>NZ_LN881739.1|WP_055642666.1|4840743_4841403_+|DUF5063-domain-containing-protein
MSDATLHSVTQDPDDFAVQIADSIESFIVATTEVAKGDEPDSAVPFMLLEISQLLLAGGRLGAHEDIVPDERYEPDTGPEPDVDDLRERFAVMLDPVDVFSEVFDPYEPRKAPVPARISDNIADIVTDLRHGLAHYRAGRTSEALWWWQFSYFSNWGPTASATLRALQSLVAHVRLDQPLAELDGLDTDEDLTEDDLAEEAGRVMLEEIAAPLGLRSKK
>NZ_LN881739.1|WP_017240166.1|4840099_4840699_+|recombination-protein-RecR
MYEGVVQDLIDELGRLPGVGPKSAQRIAFHILQAEPTDVRRLAHALLEVKEKVRFCAVCGNVAQQEQCNICRDPRRDLTVICVVEEPKDVVAIERTREFRGRYHVLGGAISPIEGVGPDDLRIRELLARLADGAVTELILATDPNLEGEATATYLARMIKPMGLKVTRLASGLPVGGDLEYADEVTLGRAFEGRRLLDV
>NZ_LN881739.1|WP_079037530.1|4839683_4840019_+|YbaB/EbfC-family-nucleoid-associated-protein
MIPGGGQPNMQQLLQQAQKMQQDLARAQAELAATEVDGQAGGGLVKATVTGSGELRGLVIDPKAVDPEDTETLADLIVAAVHAANENAQQLQQAKLGPLAQGMGGMPGLGF
>NZ_LN881739.1|WP_079037529.1|4838690_4839431_-|SLATT-domain-containing-protein
MSQQPDMQPPGQSGENSEATERPDRDLTGTPFPLGDWGEPAERLDELYRWVESNALRTAEWYLSDRIWKRRGARILRLGTAAGVIAGAALPLLDLTGAAEGAAGWGYLSLLIGAACLACDRYFGLTSGWIRDVATAQAVQRRLQALQFDWASESVREVLGPTEGTASEAAERCLGVLRRFSEDVTELVRAETADWMVEFRSGPAPLMLQSVGVVPARAESSHPSGRFPLPPGTRPNMPRQRPPEAR
>NZ_LN881739.1|WP_055642664.1|4837881_4838532_+|hypothetical-protein
MACDLWLVPLVDLLCHSPDNPFAEEIAAYDAVLSASGLPTVPVYAYMPGLSGDVAPIAGFDYEALHFLRRAYLLQVCGLPVEPVGELGGDYEQLLEMFEATAQQSHLVWHYDHAGSYVPVDFPAPLSSEELLEGGGPLGSSYGLLRELEFVAPSIGIDPMNPPALPLPPERPTSLEEPAGPIPYDDSPFARERHVWLGLHAAATRSLAQGSMIILS
>NZ_LN881739.1|WP_055642663.1|4836980_4837688_+|GntR-family-transcriptional-regulator
MPASGAVTRNTLRQQIADALRDEVLAGRLQPGQEFTVKQIAEQYGVSATPVREALVDLCAQGLLDSDQHRGFRVHQYSVDDYRRMVEARMLVVDGIFRRDAAMVPPRSVPTEPDLGVGVALVSVRRRGEAAARAARAGDLDVLIGYDIRYWRELARLVAANDYIAEFLHRLRVQAWVFSVPYLRSERDMNGWLWSGHVDLVDAITRGDAEGAVEVVRDYNTHSLEWAGYLEAQAR
>NZ_LN881739.1|WP_055642662.1|4835531_4836896_+|aspartate-aminotransferase-family-protein
MTPHVAAPDPQAGAAVKAADRAHVFHSWSAQGLIDPLAVAGAEGSYFWDYDGNRYLDFSSGLVYTNIGYQHPKVVAAIQEQAGKLATFAPAFAVDVRSEAARLIAERTPGDLDKIFFTNGGAEAVENAVRMARLHTGRHKVLSAFRSYHGATSTAINLTGDPRRWASDTGTAGVVRFWAPFLYRSPFYSENEQQECERALAHLEDTIAFEGPATIAAIILESVPGTAGIMTPPPGYLAGVREICDKYGIVFVLDEVMAGFGRTGKWFAADNFDVVPDLITFAKGVNSGYVPLGGVAINAEIAATFDKRPYPGGMTYSGHPLACAAAVATIQVMEDEKVVEHAAHIGENVLGPGLRELAERHPSVGDVRGLGVFWAIELVRDRETREPLVPYNAAGEAAAPMAAVGSTMKKNGLWPFINMNRVHAVPACNVSEAEVKEGLAALDVALSVADEYTA
>NZ_LN881739.1|WP_055642661.1|4834759_4835365_-|thiamine-biosynthesis-protein-ThiJ
MGTESATTTVHLAVYDTLADWETGHATAWLTRAGYTIRTVGPVAGEPVTTIAGIRIVPDLALDDLRPEDSALLILPGAEKYDEGDELAPFTAKARTFLDAGVPVAAICGATAGLAKEGLLDDRPHTSAVSFYLAATGYKGGEHYVDADAVTDGDLITAGPTEPVAFAREIFARLGAYEGKRDAWYRLFHDSDPAAFVELNS
>NZ_LN881739.1|WP_055642660.1|4834289_4834763_-|MarR-family-transcriptional-regulator
MSDRQQQDALSRTALGVFRLNGQFLAVSEKLAEPAGLTAAWWQVLGAVLPEPLPVAGIARVMGITRQSVQRIADLLVREGLAAYEPNPAHRRAKLLTPTEAGRAAIGRIEPGHAELAALLARELGGQEAFDETVRVLERLSGALDAVSARYTAPEAP
>NZ_LN881739.1|WP_024760130.1|4845970_4847242_+|aspartate-kinase
MGLVVQKYGGSSVADAEGIKRVAKRIVDTKKDGHQVVVVVSAMGDTTDELIDLAEQVSPIPAGREFDMLLTAGERISMALLAMAIKNLGHEAQSFTGSQAGVITDSVHNKARIIDVTPGRIRTALDEGNIAIVAGFQGVSQDKKDITTLGRGGSDTTAVALAAALDAEVCEIYTDVDGVFTADPRVVKKAKKIDWISFEDMLELAASGSKVLLHRCVEYARRYNIPIHVRSSFSGLQGTWVSNEPQGAQKVEQAIISGVAHDTSEAKITVVGVPDKPGEAAAIFRAVADAEINIDMIVQNVSAASTGLTDISFTLPKAEGRKALDELEKAKSAIGFDSLRYDDQIGKISLVGAGMKTNPGVTADFFKALSDAGVNIELISTSEIRISVVTRADDVNEAVRAVHTAFGLDSDSDEAVVYGGTGR
>NZ_LN881739.1|WP_055642669.1|4847238_4848306_+|aspartate-semialdehyde-dehydrogenase
MTPKPTLAVVGATGAVGSVMLQMLTHHADVWGEIRLLDTPGAAGSKAAVRGVECEVRALDEDSEESLDGVDLALFLVPEAVAARWAPVAVAKGAVVVDTSAAFRGDADVPLVVPEVNAHAARVRPRGIVASPGCTTLALIAAVGALHAEFGLAELVVTAQQAASGAGAGQAGVDALRAQLGLVAGDGELGTQPGDVRRAVGENSGPFPGPLALNVLPWSGTAGEDGASSEEERVRDETRRVLGLPGLRIAATCLRVPVVSGHSVSVHARFEHPVTVGRAHEVLATSPGVVLYDDPEAGDFPTPADVVGTDPAWVGRVRRSMDDERALDFFVCADNLRKGAALNALQIAESVVTDL
>NZ_LN881739.1|WP_079037531.1|4848570_4849299_+|SigE-family-RNA-polymerase-sigma-factor
MAEVLDIATIAPLRGAGTVVLPVRSAAVIPVRGSVVRPFGRPRGPGGMPVIAPVPAGSRTRAVDGIPSPRTSAEGDMAAGTTVDHLTETYRAHYRSLLGLAALLLDDTASCEDVVQEAFIRVHSARKRVREPEKTLAYLRQTVVNLSRSALRRRILGLKLLSKPMPDMASAEEGAYDQLERDDLIKAMKGLQRRQREVLVLRYFADMTEAQVAETLGISLGSVKAYGSRGIAALRVAMEANA
>NZ_LN881739.1|WP_055642670.1|4849295_4850561_+|hypothetical-protein
MSHEKDEPRAEREARAAEREARDERDDLSGRRMLNIEPGSEPDAEPDPGADTDPGSGLGDELALRRLLHGAVAGLEPTAGSLDHLRRAVPARRARKRQAVVGAAAAAVLIGTAVPAFVHVANSGGITAANPVNMGHGQDAQGGTGAETGVEGGKTSQSPASQVSPSQAAADGATGKPQQSGSGTSTQGPQVTQNPVPGDSPQCEPGQLGVSSTQTSGPDGSGSVYGTFRVANVSGQSCVVDGSGIVSFEARGAADPGKISVLRHTAGDGSGLPDPAQEATVLLLKPGGSYEVRFAWLPSETCPTSGGTPTTAPTPTTPTTQPTPTEPTPTVPPTTVPPTTTPPTTEPATQDPSAGTGGTDTGTGTDAEGGVAPQLLRADGTPADGSVSVSHTAEPGGPVAVATVPNACAGTIYRTGILAGP
>NZ_LN881739.1|WP_055642671.1|4850703_4851444_-|SURF1-family-protein
MYRFLTTPRWWGINVFVLLAIPFCVFMGTWQLGKFEDRVDSHQEAEQRPAASSLKAAPLATLLPVDKETSGRSAEARGRFGEQFLVPERDLDGRTGSYVLTLLKTDGGRSLPVVRGWLPTGAKAPAPPSGEVTVVGALQASENPGTKGAHTAGGLPEDQLGMISAAALVNVVSDDVYDAWITLTDSPAGLTPVPASAAAGTSLDVKAFQNLGYTAEWFVFAGFVLFMWFRLARREAEASRDEALGL
>NZ_LN881739.1|WP_055646192.1|4851467_4853303_-|S9-family-peptidase
MTESKDFAQIPAWEQTPVWEQRFRAPRVSLPEWAEEAPDRSLFVSNATGTYELYAWDRVSGEQRQVTDRPNGTTDGTLSPDGAWIWWFADTDGDEFGVWMRQPFAGGADEPAVPGLDASYPGGLAIGREGTLVIGRSTDEDGSTVHLVRPGAGAPVEIYRHRESAGVGDLSHDGSLIAIEHTEHGDAMHSALRVLRAADASVLAELDDTKGGTEELGLAVLGFAPVAGDSRLLVGHQRRGRWEPMLWDVAAGTETDLRLDLPGDVSAEWYPDGSGLLIVHSFEARSELFRYEIATRALVRVETPAGSVSEATARPDGSVEYLWSSAAEPPVVRSTDGSVVLDPPGPKAPPSVPVEDVWVDGPGGRVHALVQRPAEGEGPFPTVFEVHGGPAWHDSDAFASGPAAWVDHGYAVVRVNYRGSTGYGREWTDALKHRVGLIELEDVEAVREWAVSSGLADPARLVLSGGSWGGYLTLLGLGTRPDAWAVGLAAVPVADYVTAYEDEMEALKALDRTLLGGSPEEVPERYAASSPLTYVDAVKAPVHISAGVNDPRCPIRQIDNYVDRLAARGAVHEVYRYDAGHGSLVVEERIKQVALDLAFAAKHLGTRPSGA
>NZ_LN881739.1|WP_055642672.1|4853374_4854205_+|class-I-SAM-dependent-methyltransferase
MYSPTPEDWREANRARWDERVPIHASSAFYDLDAFRTGKDALRDFELAEVGDVTGRSLLHLQCHIGLDTLSWARHGAAHVVGLDFSEPAVETARSLAADLGLPQDRAAFVAADVYDAAAAVPDNAYDIVYTGGGALNWLPDIERWAETAASLVTPGGFLYVAEFHPLTDSLDDETGTRIVNDYFIREPWVDTAPGTYADLDADTVHNRSVEWVHPVGEVVTAIARAGLRIEFLHEHDASLYPRYGALQRHEDGYYRFPADRPRIPLMYSIKASRPA
>NZ_LN881739.1|WP_055642673.1|4854201_4854513_-|hypothetical-protein
MEFAVFVTLPGLVILLTVVAFADQLLRATGRGKRTGQVSSTGFEQLHATFSQGKQNELKERQSALVMRDDEEDGAPPHHSTVDLKGGRAVIRIGSPHDPEDRP
>NZ_LN881739.1|WP_055642674.1|4854562_4855594_-|AsnC-family-transcriptional-regulator
MHTGESVLGEPDLSLIHALQLAPRASWTQLSAVLGSSPDTLARRWDHLTEGGWAWSSLLVARSRDSTLYAWVELECAAGAADATAIELTDDPYTLGVHQVTGEADLVLLVVCPDLYALDVYLAGRVRRLPGVLRSRTQVVTRLHNRPYRSRIEQLAPGQVRLLTDVTGGEKRPRQSARPRMPLTDLDRALVAELAGDARRSAAELARQCGTSESTVRRRLDALMAAGALHHHCLPAPRFSGRPVWALVTADVQPLEVSSTVAALSRLRRTLLITSVTGPHNLAIATWLRTVEELHEMTSTLVRAAPTLRITGTQVSLRTRKIGAQVLGPDGRRTHHIRPDVTI
>NZ_LN881739.1|WP_055642675.1|4855906_4857304_+|hypothetical-protein
MAGATAESPESELLWGEPVSPDQLTAAEQGYESCGPAERLLWERLSVFEGAFGREAVREVCASGALPSGEIQGVLDRLAPLALLPVDDLFDGEDGAPRYWMPHPMRAVGARRLTARGDRWAVLLHHRRWCVKLARQAADWWQSGRQVDARNLALRELPDLAAAMDPTTAPLSPSAEADTSVEIAVSLWFLWVACGRVAEGRTRLRHALSLHSGPTPARALWLAAYLELESGRPEDADPLLVQAWAAAVRDGDDRCLGMLAHLRGATALFQGRSREAAAEFREALALMEEHPEFGPSRELCWVALALTLSRTDPEAAQEALDQAVLDTAARRAWTGRDLWADAWAHHARAELLSWDGERERAAEHARRALRAHLFLGTAVGAACAAELLAQMRVMVGRMTSAAHLLGAADLLRASVFEETYRPAEYCATSRDRSETLLRGLLDDRELRRAYEEGARLGLFALAGEE

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Crispr_ID: NZ_LN881739_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN881739_6

7029657-7029769

Orphan

Consensus_repeat	Method
TCATCGTCCGGCCTCCTGCGTCGTGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LN881739_6

>merge|NZ_LN881739|6|7029657-7029769|CRISPRCasFinder
TCATCGTCCGGCCTCCTGCGTCGTGTTCAGGCTGTGCTTGCCCGGGGGACGACCCCCGGACCCCCGGCAAATCTGGTGGCGCGCGTTCATCGACCGGCCTCCTGCGTCGTGTT

>NZ_LN881739|6|6|7029657-7029769|CRISPRCasFinder
TCATCGTCCGGCCTCCTGCGTCGTGTT	CAGGCTGTGCTTGCCCGGGGGACGACCCCCGGACCCCCGGCAAATCTGGTGGCGCGCGT
TCATCGACCGGCCTCCTGCGTCGTGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN881739.1\|WP_055646401.1\|7036278_7036797_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|224973
NZ_LN881739.1\|WP_055644265.1\|7019234_7020575_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|367110
NZ_LN881739.1\|WP_055646400.1\|7036039_7036243_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055644266.1\|7020670_7022212_-\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173799
NZ_LN881739.1\|WP_055644270.1\|7025680_7025896_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055644277.1\|7032247_7033024_+\|enoyl-ACP-reductase-FabI	unknown	unknown	gnl\|CDD\|236124
NZ_LN881739.1\|WP_055644279.1\|7034405_7035749_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340897
NZ_LN881739.1\|WP_055644272.1\|7026592_7026868_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_LN881739.1\|WP_055644273.1\|7026941_7028216_-\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
NZ_LN881739.1\|WP_055644268.1\|7022856_7024497_+\|cation-acetate-symporter	unknown	unknown	gnl\|CDD\|271374
NZ_LN881739.1\|WP_099054270.1\|7033261_7033684_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055644280.1\|7036881_7038096_-\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NZ_LN881739.1\|WP_055644271.1\|7026078_7026423_-\|DUF3099-domain-containing-protein	unknown	unknown	gnl\|CDD\|378630
NZ_LN881739.1\|WP_079037669.1\|7022485_7022860_+\|DUF485-domain-containing-protein	unknown	unknown	gnl\|CDD\|377315
NZ_LN881739.1\|WP_055644276.1\|7031525_7032245_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|273824
NZ_LN881739.1\|WP_055644278.1\|7033616_7034342_-\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NZ_LN881739.1\|WP_055644264.1\|7017369_7018413_+\|zinc-dependent-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|176247
NZ_LN881739.1\|WP_055644269.1\|7024661_7025663_+\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_LN881739.1\|WP_055644281.1\|7038293_7040882_+\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_LN881739.1\|WP_055646402.1\|7040963_7041764_-\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381605

Protein	Function_ID	Function_description	E-value
NZ_LN881739.1\|WP_055646401.1\|7036278_7036797_+\|histidine-phosphatase-family-protein	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	4.97041e-47
NZ_LN881739.1\|WP_055644277.1\|7032247_7033024_+\|enoyl-ACP-reductase-FabI	gnl\|CDD\|236124	PRK07889, PRK07889, enoyl-[acyl-carrier-protein] reductase FabI.	2.24681e-165
NZ_LN881739.1\|WP_055646402.1\|7040963_7041764_-\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381605	cd13402, LT_TF-like, lytic transglycosylase-like domain of tail fiber-like proteins and similar domains. These tail fiber-like proteins are multi-domain proteins that include a lytic transglycosylase (LT) domain. Members of the LT family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, and the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL). LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.22601e-30
NZ_LN881739.1\|WP_055644266.1\|7020670_7022212_-\|S8-family-serine-peptidase	gnl\|CDD\|173799	cd07473, Peptidases_S8_Subtilisin_like, Peptidase S8 family domain in Subtilisin-like proteins. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.54126e-56
NZ_LN881739.1\|WP_055644279.1\|7034405_7035749_+\|MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.30028e-125
NZ_LN881739.1\|WP_055644272.1\|7026592_7026868_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.11179e-05
NZ_LN881739.1\|WP_055644273.1\|7026941_7028216_-\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NZ_LN881739.1\|WP_055644268.1\|7022856_7024497_+\|cation-acetate-symporter	gnl\|CDD\|271374	cd11480, SLC5sbd_u4, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	0
NZ_LN881739.1\|WP_055644280.1\|7036881_7038096_-\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	7.21225e-92
NZ_LN881739.1\|WP_055644271.1\|7026078_7026423_-\|DUF3099-domain-containing-protein	gnl\|CDD\|378630	pfam11298, DUF3099, Protein of unknown function (DUF3099). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.14467e-19
NZ_LN881739.1\|WP_079037669.1\|7022485_7022860_+\|DUF485-domain-containing-protein	gnl\|CDD\|377315	pfam04341, DUF485, Protein of unknown function, DUF485. This family includes several putative integral membrane proteins.	2.58267e-35
NZ_LN881739.1\|WP_055644276.1\|7031525_7032245_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|273824	TIGR01830, 3-oxoacyl-_reductase_FabG, 3-oxoacyl-(acyl-carrier-protein) reductase. This model represents 3-oxoacyl-[ACP] reductase, also called 3-ketoacyl-acyl carrier protein reductase, an enzyme of fatty acid biosynthesis. [Fatty acid and phospholipid metabolism, Biosynthesis].	4.09223e-124
NZ_LN881739.1\|WP_055644278.1\|7033616_7034342_-\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	4.26225e-52
NZ_LN881739.1\|WP_055644264.1\|7017369_7018413_+\|zinc-dependent-alcohol-dehydrogenase-family-protein	gnl\|CDD\|176247	cd08287, FDH_like_ADH3, formaldehyde dehydrogenase (FDH)-like. This group contains proteins identified as alcohol dehydrogenases and glutathione-dependant formaldehyde dehydrogenases (FDH) of the zinc-dependent/medium chain alcohol dehydrogenase family. The MDR family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. FDH converts formaldehyde and NAD to formate and NADH. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	0
NZ_LN881739.1\|WP_055644269.1\|7024661_7025663_+\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	2.71049e-177
NZ_LN881739.1\|WP_055644265.1\|7019234_7020575_-\|CoA-transferase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	1.29445e-34
NZ_LN881739.1\|WP_055644281.1\|7038293_7040882_+\|FHA-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	9.43167e-73

>NZ_LN881739.1|WP_055644273.1|7026941_7028216_-|tyrosine--tRNA-ligase
MTDIVDELKWRGLFAQSTDEDALRKALADGPVTFYCGFDPTAASLHVGHLVQVLTVRRLQQAGHRPLALVGGATGQIGDPRPTAERTLNDPETVANWVNRLRSQIEPFLSFEGENAAVMVNNLDWTAGLSAIEFLRDIGKHFRVNKMLTKDSVARRLESEQGISYTEFSYQLLQAMDFLELYRRYGCVLQQGGSDQWGNLVAGLDLIHRLEPGADVHALATPLMVKADGTKFGKTEGGAVWLDPEMTTPYAFYQFWLNVDDRDISTYMRILSFKSREELEELEAQTAERPQARAAQRALAEELTTLVHGAEQCAAVINASKALFGQGDLAELDGATLAAALSELPHARVTELGQVVDLFTEVGLAPSKSGARRTVKEGGAYVNNVKVTAEDAEVSADELLHGRWLVLRRGKKNLAAIEFAGAEG
>NZ_LN881739.1|WP_055644272.1|7026592_7026868_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MSWLWAIIVGFVLGLIAKAILPGKQQIPLWLTTVFGILGSVLGNAVATWIGVEDTKGIDWTRHLLQLIGAVAVVGVGDMIWDSIKGNRQRA
>NZ_LN881739.1|WP_055644271.1|7026078_7026423_-|DUF3099-domain-containing-protein
MTKRGETEVFRITGARQGLADDVRGRQRRYIISMTVRTLSVIAAAVLWNVERHVAIVALALGILLPYIAVVIANAGRESAPSLPSTFVPAPVRPALGSAEAAEGAGAETPYGRN
>NZ_LN881739.1|WP_055644270.1|7025680_7025896_-|hypothetical-protein
MSEEKPICSAKGCRVDAVWVLAWNNPKLHTPERRKTWLACDEHREHLSQFLGVRGFLKDVVPLSEWEPTEG
>NZ_LN881739.1|WP_055644269.1|7024661_7025663_+|GTP-3',8-cyclase-MoaA
MLIDTYGRVATDLRVSLTDRCNLRCTYCMPEEGLQWLAKPDLLTDDEIVRLIRIAVTDLGVTEVRFTGGEPLLRPGLVGIVERVAALEPRPRMSLTTNGIGLKRTAAALKAAGLDRVNVSLDTLRPEVFKTLTRRDRHRDVLDGMAAARDAGLTPVKVNAVLMPGLNSDEAPDLLAWAIEEGYELRFIEQMPLDAQHGWKRDGMITAGDILESLRTRFTLTAEGADERGSAPAERWVVDGGPHTVGVIASVTRPFCRACDRTRLTADGQVRTCLFATEETDLRAALRAEESSPAADEVVAELWKKAMWGKKAGSGLDDPSFLQPDRPMSAIGG
>NZ_LN881739.1|WP_055644268.1|7022856_7024497_+|cation-acetate-symporter
MSSTVLLAAGNATSEHRPLIIALFGAFVVATLIITVWAGRQTRSAADFYAGGGQFTGFQNGLAISGDYMSAASFLGISGAIALYGYDGFLYSIGFLVAWLVALLLVAEPLRNSGRFTMGDVLAYRMRQRPVRTAAGTSTIVVSIFYLLAQMAGAGVLVSLLLGITSDGGKIAIVALVGILMIVYVTIGGMKGTTWVQMVKAVLLIAGTLLITFLILLKFNFNISELLGAAATNSGKGDAFLDPGLKYGASALSKLDFLSLGIALVLGTAGLPHILIRFYTVPTAKAARKSVNWAIGIIGAFYLMTIVLGFGAAALLSGDTIKASNKAGNTAAPLTALEVGGGAGSTGGAILLAVISAVAFATILAVVAGLTLASSSSFAHDIYANVIKRGKATEKEEMRAARWSTVLIGIVSIALGALARDLNVAGLVALAFAVAASANLPTILYSLFWKRFTTQGALWSIYGGLISSVVLVLFSPVVSGGPASMFKGVDFHWFPLENPGLVSIPLGFLLGWLGSLLSKEEPDAGKYAELEVKSLTGVGVAAAIKH
>NZ_LN881739.1|WP_079037669.1|7022485_7022860_+|DUF485-domain-containing-protein
MATEAPPPPRNATETDHGPVPPTTEQFVEVQQGEEFGELRRTYRSFAFPLTLAFIAWYLLYVLLSNYAGDFMSTRLFGNINVALVLGLGQFLTTFLIAWLYSRHAANSLDPRAEAIRNRMEGDA
>NZ_LN881739.1|WP_055644266.1|7020670_7022212_-|S8-family-serine-peptidase
MAHLGSRRGRALALPAGLALTASLGFLPSGAASAAELSDAPAAAVAATNGPKLSYVVNVAGGRWTAASVKKAIAAAGGEVVIAYDQIGVIVVHSQNPEFAKTIRQARGVVSAGSTRTAPLSAQADASVDEGAQTLTAAEAKAAAATATDEQDPLEPLQWDLPAIKADKAHQKTLGSKRVTVGVIDTGVDDTHPDLAPNFDVKASANCVTGKPDTTPGSWRPNPGESDHGTHVAGTIAAAKNGVGVTGVAPGVKVSGIKVSTPDGFFYTEAVVCGFVWAAEHGVDVTNNSYYTDPWMFACKNDEDQKALIEAVTRASRYAEKKGTVNVAAAGNSKFDLAADSILDNSSPNDTTPGDRVIDPKVCLDYPGMLPGVVTVSATGAKDLKASYSNYGLGVIDVSAPGGDRTEYQTPDAPAVNGRILSTTVNGGYNYKAGTSMAAPHAAGVLALIKSTHPYASPAALKALLYAQADDRACTNPYDIEGDGKIDAVCEGGKNKNGFYGAGLIDALDAVRR
>NZ_LN881739.1|WP_055644265.1|7019234_7020575_-|CoA-transferase
MDNTPRSGTELLWSVLGGDPALVDHVEYGGTSGLLPARLPVMDLARATVAVCSLAAVEHAGLPGPVRVDDGAVATAFVSERHLRVDGRAPVNFAPLSRFWRAADGWVRTHANYPHHRVALLAALGVGDPVEAVATGEAVDAVDAVDAVAAAIGERKAVEVESAVYAAGGLAVALRTPSEWAEHPQGREVAARPLLSRERLDDAPPRRRSGPLRVLDLTRVIAGPVATRTLALLGADVLRIDPPGNPELPDQHADAGVGKRTAALDLERPSDRRTLDELLDSADVLVTGYRPGALDRFDLDRPGLVTARLSAWGDYGPWGERRGFDSLVQVATGIAVTEGSAEEPGALPAQALDHGTGYLLAAAVLRSLTEQRAEGGSRLVRLALAQTGHWLTTALPRYEPERYLAESEGPLGRLRHALSPVSYEGGPTGWSRPPGVAGADAAEWRG
>NZ_LN881739.1|WP_055644264.1|7017369_7018413_+|zinc-dependent-alcohol-dehydrogenase-family-protein
MRATTIHAPFDMRVEDVPDPVIQDSTDVVLRVLRACICGSDLWAYRGESARQPGQRIGHEFLGIVEAAGSDVTGFAAGDLVVAPFVWSDGTCEYCAEGLQTSCPRGGFWGSVGSDGGQGEAVRVPFADGTLVKLPADAASDDHLLTALLALSDVLGTGHHAALGAGVKPGSTVAVVGDGAVGLCGVLAAKRLGAERIIALGRHTARTDIARAFGATDVVAERGEAAEAAVRELTGGQGAHGVIEAVGTEQSMRTAVAITRDGGSIGYVGVPHGSGTGLDLSVMFDRNIALRGGVAPVRAYIPELLPDVLAGTIDPSPVFDLTVDLNGVPAGYKSMDDRTALKVLVKP
>NZ_LN881739.1|WP_055644276.1|7031525_7032245_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MSRSVLVTGGNRGIGLAIARAFAEAGDKVAITYRSGEPPAALVELGCLPVKCDITVAEQVEQAYKEIEEKHGPVEVLVANAGVTKDQLLMRMSEEDFTSVVDTNLTGTFRVVKRANRGMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFVDTDMTAVLTDEQRAGIVSQVPLGRYAQPEEIAAAVKFLSSDDASYITGAVIPVDGGLGMGH
>NZ_LN881739.1|WP_055644277.1|7032247_7033024_+|enoyl-ACP-reductase-FabI
MSGILEGKRILITGVLMESSIAFHTAKLAQEQGAEIILTAWPRPTLTERIAKKLPHPENVKVLELDVSNDEHLARLEGQVREQFGDRLDGIVHSIGFAPQDALGGNFLNTPFESVATAMHVSAFSLKSLTMALLPLMSEGGSVVGLTFDAKFAWPQYDWMGPAKAALEATSRYMARDLGKQNIRCNLISAGPLGSMAAKSIPGFGELAAVWDTRSPLQWELSDPEPAGRGVVALLSDWFPKTTGEIIHVDGGLHAIGA
>NZ_LN881739.1|WP_099054270.1|7033261_7033684_+|hypothetical-protein
MRAIRHGFGAFASVAVLLTGIAVAAEVRAAPAPAEELPAAAPPADEPENFGASCRTVVQGSRVTAYCQNPYPGTDRVRLHVECDRWWDVDTDSAPVDVGPADYAQISGRCWKEVRSAWVTHQPAEPEPAPAQEPAPVRGS
>NZ_LN881739.1|WP_055644278.1|7033616_7034342_-|FadR-family-transcriptional-regulator
MALGHPRRAGLSDQVIAELRNQITSGEWPVGSRIPTEPELVEQLGVARNTVREAVRALAHNGLLDIRQGSGTYVIATSELAGVMHRRFAGSDPRHVAELRSTLESAAARFAAERRTERDLKQLDALLVRREEAWESGDAERFVTVDAAFHHAVVAASGNDVLTELYADLGDLLRDWLRDDVGQELRPENHMDHARLVDAIREGDAERAGTEAAGYPFMCLKSPVPEPVPAPEPVPVPPAGA
>NZ_LN881739.1|WP_055644279.1|7034405_7035749_+|MFS-transporter
MPDEPKTLDPAPAPTPATATTTRNSSAPALASGFPQASASRWTLGLVTVGLVLAALNLRPAITSLGALLEEVSAGLHMSGTVAGVLTSVPPLCFAVFGITAPRLARRFGPVAVVCAGMAAIFAGLAVRPFASGTAGFLAASALALMGIALSNVLMPVIVKRYFPDRVGTMTGLYSMALALGTSVAAAATVPMTEALGGDWRAGLGVWAVVAALAVLPWIPLLRDRDRDRGGLPTRAGRATGKATASAVPLDTAPAPRVTRSRTAWALGCFFGLQATGAYITMGWMPQIFRDAGVPASTAGVLLAVTMVMGVPLAFVIPRLATRMKTQGPIVVALGLCGLGGYTGLFFAPASGAWIWAVLLGVSNCAFPLALTMIGMRSRTGAGVVRLSAFAQSVGYLISIPGPLLVGVLYQHSGGWGLPIALMGGLMVPQMIIGTLAGRDRTVEDEC
>NZ_LN881739.1|WP_055646400.1|7036039_7036243_+|hypothetical-protein
MSARTDTSTRPMPTRVDTRLPWWALALPVAAFVALLLLIAGPGGAQATADDQGVGRVLVQLQQTLAP
>NZ_LN881739.1|WP_055646401.1|7036278_7036797_+|histidine-phosphatase-family-protein
MSVDTPRRIALLRHAKADWNQESDHERPLADRGRADAPVVGRRLAETGIGFDLALCSTALRTRETWKLAVHELPERPRTVYEERLYEASLGELIALINETPEDVDDLLLIGHNPGMHALADALAGEAEGDVQSRMNRSGFPTSAFAVLTFNGSWKSVELGVARLSHFWAPHA
>NZ_LN881739.1|WP_055644280.1|7036881_7038096_-|phosphoserine-phosphatase-SerB
MSASQTSDVPTLLVKIFGKDRPGITAGLFDTLAAYSVDVVDIEQVVSRGRLVLCALVTEPTVASQGELRATIHSWAESLKLQAEIISGTGDNRPRGEGRSHVTVLGNPLTAEQTAAIAARIAESGGNIDRIFRLAKYPVTAVEFAVSGCETEPLRTALATEAHTIGVDVAVVSAGLHRRAQRLVVMDVDSTLIQDEVIELFAAHAGCEDKVAEVTAAAMRGELDFEQSLHARVELLAGLDASVVDKVRAEVRLTPGARTLIRTLKRLGYQVGVVSGGFTQVTDDLKERLGLDFASANTLEIVDGKLTGRVTGEIVDRAGKARLLRRFATEAGVPLAQTVAIGDGANDLDMLNAAGLGVAFNAKPVVRRAADTAVNVPFLDTVLYLLGITREEVEVADGGEDLLH
>NZ_LN881739.1|WP_055644281.1|7038293_7040882_+|FHA-domain-containing-protein
MGLGVPELVLELNGRTWTLDPSRSYTLGRDPQGDLVIDDARVSWRHATISWGGRSWVIEDHGSTNGTFVQGQRIHQMEIGPGSAVNLGNATDGPRLNLAASGAAAVPQQQAPAHQAPAHQPAAAAQADWATHQAPPQQQGWPQQGAQGGHAPAHQQVPHQQGPAGYPGQGGPVEQLAQKVPGGGPAGASSAYSDRSPTTFHALNLGHVMRIGRALENELVVSDLQVSRHHADFHATPDGRFEIRDLGSHNGTYVNGQPIPKGGSAVLGPQDIVGVGHSTFRIVGGQLEEFVDTGSVSFSARHLTVTVDGGKQILRDVTFGVPEKSLIGVIGPSGSGKSTLLKALTGYRPANEGDVLYDNRSLYKQFAELRQRIGLVPQDDILHKELTVVKALRYAAKLRFPGDTATAEREARIDEVLRELKLDIHKEKKVTSLSGGQRKRVSVALELLTKPSLIFLDEPTSGLDPGMDRDVMQLLRGLADDGRTVLVVTHSVAELGLCDKLLVMAPGGSVAYFGPPEEALNFFGYSTWADVFSAFENYRDYDWAGRWKGSQHYQMYAADIDAVAAQPVQMPQQAMARPPKPQGWGSQLWTLIRRYVSVIASDKGFLGLMVILPAVLGAVSVVIPADFGLGSPTPPSRFNGDAGTIMLILAVGMCFSGAANSVRELIKERVIYERERATGLSRSAYLMSKVIVLGLITAFQGVIICGIGFSTRALPAEGLFMPPAVELCIQVIALGLTSMMFGLVISALVKTAEKTMPLLVMFAIIQVVFTGILFQVYGSPGLEQFAWLMPSRWGIAGAGTTLDLARLMPPWDHKNPTDTDPLWEHTVGQWSLDLGIQLLMAVVCCVVVARLLRRHEPEVMRK
>NZ_LN881739.1|WP_055646402.1|7040963_7041764_-|transglycosylase-SLT-domain-containing-protein
MMSANTPGHSRGLKKTHKATIAGVAALSAAALTLSLVQGNGGSTETEPQALSGTQQVAWSYNAASPQAKALAASVTEQQTTIGLKAKQEAVAKAAAKAKADAKAKADAQAAAKAKAAAKAKADAQAAAKAKAAAKAKADAKKRAAEKAAASRSVARTPVFANNLDGWIREALFIMDKHNIPGTYNGLHKNIMRESSGNPRAINNWDINAINGVPSKGLLQVIYPTFKAYHIPGTKFDQYDPVANLVAAANYAADRYGSIDNVNSAY

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Crispr_ID: NZ_LN881739_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN881739_7

7058853-7059356

Orphan

Consensus_repeat	Method
GACAACCGNGGNGGNGGCNNN	CRT

11 spacers

The CRISPR arrays of NZ_LN881739_7

>merge|NZ_LN881739|7|7058853-7059356|CRT
GACAACCGCGGTGGCGGCACCGGTGGTGGCTTCCGTCGTGACGACAACCGCGGTGGCGGTTCCGGCGGTGGCTTCCGTCGGGACGACAACCGTGGCGGTGGCTCCGGCGGTGGCTTCCGTCGCGATGACAACCGCGGTGGCGGCACCGGCGGCGGTTTCCGTCGTGACGACAACCGTGGCGGTGGCACCGGTGGTGGCTTCCGTCGTGACGACCGTCGTGACGACAACCGCGGTGGCGGCTCCGGTGGTGGCTTCCGTCGCGATGACAACCGCGGTGGCGGCTCCGGTGGTGGCTTCCGTCGTGACGACAACCGCAGTGGCGGCTCCGGTGGTGGCTTCCGTCGCGATGACAACCGTGGCGGCGGTTCCGGCGGCGGTTTCCGTCGTGACGACAACCGTGGCGGTGGCACCGGTGGTGGCTTCCGTCGTGACGACCGTCGTGACGACAACCGCGGTGGCGGCTCCGGTGGTGGCTTCCGTCGCGATGACAACCGCGGTGGTGGC

>NZ_LN881739|7|1|7058853-7059356|CRT
GACAACCGCGGTGGCGGC	ACCGGTGGTGGCTTCCGTCGTGAC
GACAACCGCGGTGGCGGT	TCCGGCGGTGGCTTCCGTCGGGAC
GACAACCGTGGCGGTGGC	TCCGGCGGTGGCTTCCGTCGCGAT
GACAACCGCGGTGGCGGC	ACCGGCGGCGGTTTCCGTCGTGACGAC
AACCGTGGCGGTGGCACC	GGTGGTGGCTTCCGTCGTGACGACCGTCGTGAC
GACAACCGCGGTGGCGGC	TCCGGTGGTGGCTTCCGTCGCGAT
GACAACCGCGGTGGCGGC	TCCGGTGGTGGCTTCCGTCGTGAC
GACAACCGCAGTGGCGGC	TCCGGTGGTGGCTTCCGTCGCGAT
GACAACCGTGGCGGCGGT	TCCGGCGGCGGTTTCCGTCGTGAC
GACAACCGTGGCGGTGGC	ACCGGTGGTGGCTTCCGTCGTGACGACCGTCGTGAC
GACAACCGCGGTGGCGGC	TCCGGTGGTGGCTTCCGTCGCGAT
GACAACCGCGGTGGTGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN881739.1\|WP_055644289.1\|7050069_7050576_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|224321
NZ_LN881739.1\|WP_079037963.1\|7061084_7062323_-\|DUF1015-domain-containing-protein	unknown	unknown	gnl\|CDD\|377633
NZ_LN881739.1\|WP_079037671.1\|7063622_7064675_+\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl\|CDD\|182464
NZ_LN881739.1\|WP_055644290.1\|7050741_7051281_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|182339
NZ_LN881739.1\|WP_055644286.1\|7046774_7047572_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_LN881739.1\|WP_055644292.1\|7052206_7052869_+\|DNA-3-methyladenine-glycosylase	unknown	unknown	gnl\|CDD\|234840
NZ_LN881739.1\|WP_099054267.1\|7065744_7066590_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NZ_LN881739.1\|WP_055644301.1\|7066578_7066926_-\|sterol-binding-protein	unknown	unknown	gnl\|CDD\|376720
NZ_LN881739.1\|WP_055644299.1\|7064671_7065706_+\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl\|CDD\|227119
NZ_LN881739.1\|WP_055644291.1\|7051336_7052119_-\|sporulation-protein	unknown	unknown	gnl\|CDD\|369195
NZ_LN881739.1\|WP_024756199.1\|7048173_7049112_+\|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl\|CDD\|223407
NZ_LN881739.1\|WP_055644303.1\|7067251_7068067_+\|TlyA-family-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|224110
NZ_LN881739.1\|WP_055644293.1\|7052995_7053232_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055644288.1\|7049210_7049978_+\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_LN881739.1\|WP_099054268.1\|7045835_7046639_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055644304.1\|7068063_7068984_+\|NAD-kinase	unknown	unknown	gnl\|CDD\|235121
NZ_LN881739.1\|WP_055644287.1\|7047648_7048080_+\|NfeD-family-protein	unknown	unknown	gnl\|CDD\|224501
NZ_LN881739.1\|WP_079037670.1\|7060223_7061024_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|235640
NZ_LN881739.1\|WP_055644302.1\|7066968_7067244_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN881739.1\|WP_055644297.1\|7062462_7063539_+\|HAD-hydrolase-like-protein	unknown	unknown	gnl\|CDD\|319832

Protein	Function_ID	Function_description	E-value
NZ_LN881739.1\|WP_055644289.1\|7050069_7050576_-\|HNH-endonuclease	gnl\|CDD\|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	1.38839e-17
NZ_LN881739.1\|WP_079037963.1\|7061084_7062323_-\|DUF1015-domain-containing-protein	gnl\|CDD\|377633	pfam06245, DUF1015, Protein of unknown function (DUF1015). Family of proteins with unknown function found in archaea and bacteria.	2.61268e-128
NZ_LN881739.1\|WP_079037671.1\|7063622_7064675_+\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl\|CDD\|182464	PRK10441, PRK10441, Fe(3+)-siderophore ABC transporter permease.	1.54555e-100
NZ_LN881739.1\|WP_055644290.1\|7050741_7051281_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	3.90151e-59
NZ_LN881739.1\|WP_055644286.1\|7046774_7047572_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.78607e-92
NZ_LN881739.1\|WP_055644292.1\|7052206_7052869_+\|DNA-3-methyladenine-glycosylase	gnl\|CDD\|234840	PRK00802, PRK00802, DNA-3-methyladenine glycosylase.	9.72243e-90
NZ_LN881739.1\|WP_099054267.1\|7065744_7066590_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	2.01358e-136
NZ_LN881739.1\|WP_055644301.1\|7066578_7066926_-\|sterol-binding-protein	gnl\|CDD\|376720	pfam02036, SCP2, SCP-2 sterol transfer family. This domain is involved in binding sterols. It is found in the SCP2 protein, as well as the C-terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.	2.46768e-05
NZ_LN881739.1\|WP_055644299.1\|7064671_7065706_+\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl\|CDD\|227119	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism].	3.25972e-105
NZ_LN881739.1\|WP_055644291.1\|7051336_7052119_-\|sporulation-protein	gnl\|CDD\|369195	pfam07070, Spo0M, SpoOM protein. This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH.	3.78772e-108
NZ_LN881739.1\|WP_024756199.1\|7048173_7049112_+\|SPFH/Band-7/PHB-domain-protein	gnl\|CDD\|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	3.00877e-66
NZ_LN881739.1\|WP_055644288.1\|7049210_7049978_+\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	6.96002e-23
NZ_LN881739.1\|WP_055644303.1\|7067251_7068067_+\|TlyA-family-RNA-methyltransferase	gnl\|CDD\|224110	COG1189, COG1189, Predicted rRNA methylase [Translation, ribosomal structure and biogenesis].	5.28612e-103
NZ_LN881739.1\|WP_055644304.1\|7068063_7068984_+\|NAD-kinase	gnl\|CDD\|235121	PRK03372, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	6.27401e-168
NZ_LN881739.1\|WP_055644287.1\|7047648_7048080_+\|NfeD-family-protein	gnl\|CDD\|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	1.6454e-14
NZ_LN881739.1\|WP_079037670.1\|7060223_7061024_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	4.06078e-05
NZ_LN881739.1\|WP_055644297.1\|7062462_7063539_+\|HAD-hydrolase-like-protein	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.10645e-91

>NZ_LN881739.1|WP_055644293.1|7052995_7053232_-|hypothetical-protein
MDGVSTNLALIFGTLLSSQGADASFVLTLAGFPPGFSFVPKPIRSFRSDFLGAFRSLSFSLRGPFGVVTTLADFSGDS
>NZ_LN881739.1|WP_055644292.1|7052206_7052869_+|DNA-3-methyladenine-glycosylase
MSDTPSRTRLPRAFFDRPVLDVAPDLLGRTLVRNTPEGRIELRLTEVEAYAGAIDPGSHAFRGRTARNAVMFGPPGHAYVYFTYGMWHCLNLVCGPEGQASGVLLRAGEVLTGAEQARARRRSARHDRELAKGPARLATALDIALSLNGTDTCAGSTAPLTLLTGTPPTPEAISSGPRTGVGGDGAPHPWRFWITDDPTVSPYRPHTPRKRRLDSGRPTA
>NZ_LN881739.1|WP_055644291.1|7051336_7052119_-|sporulation-protein
MGFKKLLASLGAGGATVETVLSEANVVPGGVVQGEVRIQGGSVDQQIEALSVGLQARVEVEGGDQEHKQDIEFLKVRLGGAFEVKAGAVHVVPFGLEVPWETPVTSVSGQQLHGMNIGVVTELEIARAVDSGDLDPINVHPLPAQQAILDAFIGLGFRFKSADMERGHIRGTRQKLPFYQEIEFFAPQQYRGLNQVEVSFVADEREMDVVLEMDKKPGLFGEGSDSFRAFKVGLHDFHTTDWAAYLNQWLAEVGGRRNWL
>NZ_LN881739.1|WP_055644290.1|7050741_7051281_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MSEGKRAPLPHDFHPPVAEFTVVSDDVTPGGVLKDAQVYAAGNTSPHLRWEGFPEGTKSFAVTCFDPDAPTGSGFWHWVLFDVPVSVTELPVGAGSGSFKGLPAGAVQVRNDYGAKEFGGAAPPAGDPAHRYVFTVYAVDSEKLGPDDGASPAAIGFNLRFHTLGRAQLVAEYAAPAAV
>NZ_LN881739.1|WP_055644289.1|7050069_7050576_-|HNH-endonuclease
MRDTLVLNASFEPLSTVTLNRAVVLVLQDKAVVEQAHPELRVRGAAVDLPVPRVIRLCRYVRVPFRRHAPWSRRGVLVRDQHRCAYCGRRATTVDHVVPRAQGGGDSWLNTVASCAEDNHRKADRTPEQAGMPLLHEPFVPSPADAMLLALRAGERSALPEWLANSAA
>NZ_LN881739.1|WP_055644288.1|7049210_7049978_+|sulfite-exporter-TauE/SafE-family-protein
MSIWEALAVFAAGIGAGTINTIVGSGTLITFPVLLATGLPPITANVSNALGLVPGSISGAIGYRRELKGQKARIIRLGGVALLGGLIGAILLLALPSDAFDAIVPVLIGLALVLVLLQPRIAAAVQRRREQSGTVAHPDGGPVLLVGLCLASMYGGYFGAAQGVLYLSLMGLLLHDTLQRINAVKNILGALVNGIAAVFFLFVAEFDWTAVLLIAVGSTIGGQIGAKVGRKLPPSVLRGVIIAVGIVAILQLTLK
>NZ_LN881739.1|WP_024756199.1|7048173_7049112_+|SPFH/Band-7/PHB-domain-protein
MSAVIIVLIILVVLVFIALVKTIQVIPQASAAIVERFGRYTRTLNAGLNIVVPFIDSIRNRIDLREQVVPFPPQPVITQDNLVVNIDTVIYYQVTDARAATYEVASYIQAIEQLTVTTLRNIIGGMDLERTLTSREDINAALRGVLDEATGKWGIRVNRVELKAIEPPTSIQDSMEKQMRAERDKRAAILTAEGTRQSAILTAEGEKQSAILRAEGESRAAALRAEGEAQAVRTVFEAIHAGDPDQKLLSYQYLQMLPKIAEGDANKLWIVPSEIGDALKGLSGAFGNVGGGAPGFNTKDVPAARREEPPVD
>NZ_LN881739.1|WP_055644287.1|7047648_7048080_+|NfeD-family-protein
MDIDAWVWWLIGAVGLGIPLVLTAMPEFGMFSVGAVAGAVTAALGFGIVPQVLVFVVVSVALIAVVRPIAARHRDGRPRHASGIDALKGRQAVVLERVDVGGGGRIKLAGEIWSARALDSGQTFEPGDQVDVVEIDGATAVVM
>NZ_LN881739.1|WP_055644286.1|7046774_7047572_+|ABC-transporter-ATP-binding-protein
MSDVLELVDVSVVRDGRALVDEVSWSVKEGERWVILGPNGAGKTTLLNIASSYLFPTKGTATILGEPLGGVGTDVFELRPRIGMAGIAMAEKLPKGQTVLQTVLTAAYGMTATWHEDYDPVDEQRAKAFLDRLGMNDYLDRKFGTLSEGERKRTLIARAMMTDPELLLLDEPAAGLDLGGREDLVRRLGRLARDPYAPSMIMVTHHVEEIAPGFTHVLMIRQGKVLAAGPVEMELTSRNLSLCFGLPLVVERVGDRWTAQGLPLK
>NZ_LN881739.1|WP_099054268.1|7045835_7046639_-|hypothetical-protein
MLSEPRSGRLAAWGNALLAGAVSPDDAALAIVGEDAVHRVEGLPGEAAPVGLTLALGRLRRLGVTGWRVALPAPGHPLGLSGPPEFNARALEAAEAVVGFGAPYGLVPEVSEAGPAGDVHVEVVWHCLPVREAPPADVPSLGEAERELAEALRDATAVLTKLDVAASGPAADAAREAYRARAEVGREVLAPGYPPRAVRVLELAQRIGLLVDLAYDHGHGGAVSASEMAARREALRPVERVARRAQVAAYNAYVEESEREKERERGF
>NZ_LN881739.1|WP_079037670.1|7060223_7061024_+|tetratricopeptide-repeat-protein
MRQELMSLPKGLAEDVSRNLVMVAQLIDDEPEKAYEYSRVALRLASRVAAVREAAGFAAYATQKYSEALAEFRAARRMSGGVELWPVMADCERGLGRPERALAMAGEPEVQKLDKAGQVEMRLVAAGARRDLGQLDAAIVTLQSPELASGAVHPWTARLRYAYADALLAAGRESEARDWFAKALESDKDGVTDASDRLAELDGIEFVDAFDDSDDEDDVQDVEDIEDDVEDVEDADDVEDVEDVEGGVVDVADDVDEVEDVDGDDR
>NZ_LN881739.1|WP_079037963.1|7061084_7062323_-|DUF1015-domain-containing-protein
MAPFRGLRYVPERVGSLAAVTSPPYDVVVRPDGLLHLESADPHNIVRLILPQAITAGTRHRKAAVTLDRWLADGVLAPDPEPALYVYEQSGDGILQRGIIGALELSTPDEGVVLPHEDVMPHVVEDRAALMRTTAANLEPLLLTYVGEDDGGADAVIERAVLREPLLSTTTEDGFHHRLWSVTDPAEQATVAEELRRHQALIADGHHRWATYLRLREEHTAPGPWNYGLVLLIDTARYPLRVRAIHRLLNRLPVADALAALGDSFRVRRIEGPLPTALEALATAAAEGNAFLLAGDGAFHLLDRPDPALLDRTIRADRPEAWRTLDATVLHSTLLEQIWHIPDAPEDIAYIHDTEAAVAQAERRGGTAVLMHPVREEVVRDLARQGVTMPRKSTSFGPKPATGLVLRSLALD
>NZ_LN881739.1|WP_055644297.1|7062462_7063539_+|HAD-hydrolase-like-protein
MTVRNGQGQHDGGGRRLPGSSAVALSAAYDTALLDLDGVVYAGGEAIPYAVEALGVAREGGMHLAYVTNNALRTPEEVATHLTDLGVPAVAGDVVTSAQAVARLIAEEVPPGSRVLVVGGEGLQVALRERGLVPVESADFEPAAVVQGYGGPDLPWGRFAEAAYAVQRGVPWYASNTDLTIPGARGIGPGNGAAVEVVRIASGGRAEPKVAGKPLPPMHRETVLRTGAARPLVVGDRLDTDIEGAFNGGVDSLLVLTGVTDVAQLLTAVPEHRPTYVAADLRGLLVGQPEVVEGAGGVFACGAWRASVSGGELVLEAASEGGADVMDGVRALCGAAWSAAGDGVCGADAGKALASLGW
>NZ_LN881739.1|WP_079037671.1|7063622_7064675_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MVESPSRASADPTPTAPTATRRNSVRAVGLVVAVAVLLLVCVLSIMIGAKPVPLGDVWHGLFENSGVGNDVVIHDVRVPRTLLGLLVGLALGLSGAVMQGLTRNPLAEPGLLGVNAGAAAAVVSAIAFLGVVDVKEYVWFAFVGAAVVAVVVYLLGGSRSATPVRLALAGTAATAALYGYVNAVELLNSAALDRMRFWTVGSLASADMATIRQVAPFILTGAVLALLIARPLNAMEMGDDTARALGANINRTRVVAMVAVTLMCGAATAACGPIVFLGLMVPYMVRAITGPDMRWILPYAAVLAPVLLLGSDVVGRLVARPSELQVGIVTALIGGPVFIRLVRRKRMAQL
>NZ_LN881739.1|WP_055644299.1|7064671_7065706_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MTTKTLRAGGGLSVRYEPRAALSVLGLLVLTVAVAVVLIGTGDFPMTPGEVVDTLLGKGTVVQEFAVMDLRLPRVLVAVFVGAALAVGGAVFQSVSRNPLGSPDVIGFGQGATVGALTVIVLFQGSAAAAAGGAVVGGLVTGVTIYLLAWKKGVHGYRLVLVGIGAAAMLTSVIHYLITKANLVDATRATVWMTGSLDGRDWSQFWPLFAVCCVLLPLVLGHGRALRMLEMGDDAAYALGVKVERTRIVLMASAVVLVAVATSAAGPIVFVSLSAPQLARRLTRAPGPNLAASALMGSALLLSADWIATNAFGERQLPVGVVTGILGGCYLLWLLVTERKAGRI
>NZ_LN881739.1|WP_099054267.1|7065744_7066590_+|ABC-transporter-ATP-binding-protein
MTGRQKQRLSAESVTLAYEQRVIARDLSVEIPDNSFTVIVGPNACGKSTLLRALSRMLKPAEGRVLLDGASIHSLPAKKVAKTLGLLPQSSIAPDGITVADLVARGRYPHQGLLRQWSPEDERIVQESMASTGVAELADRYVDELSGGQRQRVWIAMALAQQTPLLLLDEPTTFLDIQHQIDVLDLCAELHETQGRTLVAVLHDLNHAARYATHLIAVRGGEVVAEGPPSEVVTAELVERVFGLRCQVIEDPETGTPLVVPAGRKARARDTGAAQKPALQK
>NZ_LN881739.1|WP_055644301.1|7066578_7066926_-|sterol-binding-protein
MATITECRGALDRLSDSLARADGDVRGATALDRTLSCHITDLDTTFTGRLADGRIEVEDTVPGPPPAKAQIRLAMTGDDLVAMVGGELNFAKAWASGRVRLEAGFRDLLKLRSLL
>NZ_LN881739.1|WP_055644302.1|7066968_7067244_+|hypothetical-protein
MSDATTEQGPDEREAAGAAEDHEPAAPAPLGIARELTGHAAVDAHLARLAEVDHLPADGHLEVYEDVHRGLRAELTSLDAHPAPRPHDNRS
>NZ_LN881739.1|WP_055644303.1|7067251_7068067_+|TlyA-family-RNA-methyltransferase
MAGVARRRLDAELVRRKLARSREHASQLIAAGRVTVGKTVATKPATQVETAAAIVVVQDDSDPDYVSRGGHKLAGAFEAFVPQGLRVEGRRALDAGASTGGFTDVLLRAGAAHVVAVDVGYGQLAWSLQSDERVTVKDRTNVRELTLDAIDGVPVDLVVGDLSFIPLGLVLPALAACTAPDADLVLMVKPQFEVGKERLGTGGVVRSSELRADAVKNVARRAAELGLGVLGVTASPLPGPSGNVEYFLWLRAGAPALDPADVDRAVAEGPS
>NZ_LN881739.1|WP_055644304.1|7068063_7068984_+|NAD-kinase
MSSTAAPSGTSRTVFLLAHTGRPAAVRSAELVVLGLLRCGIGVRVLEAEASDLPLPPSVEKVPEACSDALDGCELLVVLGGDGTLLRGAEFSRASGVPMLGVNLGRVGFLAEAERDDLDKVVDRVVTKAYEVEERMTLDVVVYENGDVLHRDWALNEAAVQKVSPERMLEVVLAIDGRPVTGFGCDGVICATPTGSTAYAFSAGGPVVWPEVEALLMVPIGAHALFAKPLVTTPESVLAVEVEPHTPHGVLWCDGRRTVELPAGARVEVRRGAVPVRLARLHHASFTDRLVAKFALPVSGWRGAPH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LN881739_3	3.5\|1845004\|21\|NZ_LN881739\|CRISPRCasFinder	1845004-1845024	21	NZ_LN881739.1	1845034-1845054	0	1.0
NZ_LN881739_7	7.1\|7058871\|24\|NZ_LN881739\|CRT	7058871-7058894	24	NZ_LN881739.1	7059825-7059848	0	1.0
NZ_LN881739_7	7.6\|7059093\|24\|NZ_LN881739\|CRT	7059093-7059116	24	NZ_LN881739.1	7059783-7059806	0	1.0
NZ_LN881739_7	7.8\|7059177\|24\|NZ_LN881739\|CRT	7059177-7059200	24	NZ_LN881739.1	7059783-7059806	0	1.0
NZ_LN881739_7	7.11\|7059315\|24\|NZ_LN881739\|CRT	7059315-7059338	24	NZ_LN881739.1	7059783-7059806	0	1.0
NZ_LN881739_3	3.1\|1844794\|20\|NZ_LN881739\|CRISPRCasFinder	1844794-1844813	20	NZ_LN881739.1	7520163-7520182	1	0.95
NZ_LN881739_7	7.1\|7058871\|24\|NZ_LN881739\|CRT	7058871-7058894	24	NZ_LN881739.1	7059357-7059380	1	0.958
NZ_LN881739_7	7.1\|7058871\|24\|NZ_LN881739\|CRT	7058871-7058894	24	NZ_LN881739.1	7059510-7059533	1	0.958
NZ_LN881739_7	7.3\|7058955\|24\|NZ_LN881739\|CRT	7058955-7058978	24	NZ_LN881739.1	7059783-7059806	1	0.958
NZ_LN881739_3	3.1\|1844794\|20\|NZ_LN881739\|CRISPRCasFinder	1844794-1844813	20	NZ_LN881739.1	5367237-5367256	2	0.9
NZ_LN881739_3	3.1\|1844794\|20\|NZ_LN881739\|CRISPRCasFinder	1844794-1844813	20	NZ_LN881739.1	7124065-7124084	2	0.9
NZ_LN881739_3	3.1\|1844794\|20\|NZ_LN881739\|CRISPRCasFinder	1844794-1844813	20	NZ_LN881739.1	8235069-8235088	2	0.9
NZ_LN881739_3	3.1\|1844794\|20\|NZ_LN881739\|CRISPRCasFinder	1844794-1844813	20	NZ_LN881739.1	8276921-8276940	2	0.9
NZ_LN881739_3	3.1\|1844794\|20\|NZ_LN881739\|CRISPRCasFinder	1844794-1844813	20	NZ_LN881739.1	5739593-5739612	2	0.9
NZ_LN881739_7	7.2\|7058913\|24\|NZ_LN881739\|CRT	7058913-7058936	24	NZ_LN881739.1	7059468-7059491	2	0.917
NZ_LN881739_7	7.5\|7059042\|33\|NZ_LN881739\|CRT	7059042-7059074	33	NZ_LN881739.1	7059936-7059968	2	0.939
NZ_LN881739_7	7.6\|7059093\|24\|NZ_LN881739\|CRT	7059093-7059116	24	NZ_LN881739.1	7059741-7059764	2	0.917
NZ_LN881739_7	7.7\|7059135\|24\|NZ_LN881739\|CRT	7059135-7059158	24	NZ_LN881739.1	7059468-7059491	2	0.917
NZ_LN881739_7	7.8\|7059177\|24\|NZ_LN881739\|CRT	7059177-7059200	24	NZ_LN881739.1	7059741-7059764	2	0.917
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_LN881739.1	7059468-7059491	2	0.917
NZ_LN881739_7	7.11\|7059315\|24\|NZ_LN881739\|CRT	7059315-7059338	24	NZ_LN881739.1	7059741-7059764	2	0.917

1. spacer 3.5|1845004|21|NZ_LN881739|CRISPRCasFinder matches to position: 1845034-1845054, mismatch: 0, identity: 1.0

gccgggcgggctcgcgtctgg	CRISPR spacer
gccgggcgggctcgcgtctgg	Protospacer
*********************

2. spacer 7.1|7058871|24|NZ_LN881739|CRT matches to position: 7059825-7059848, mismatch: 0, identity: 1.0

accggtggtggcttccgtcgtgac	CRISPR spacer
accggtggtggcttccgtcgtgac	Protospacer
************************

3. spacer 7.6|7059093|24|NZ_LN881739|CRT matches to position: 7059783-7059806, mismatch: 0, identity: 1.0

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggcttccgtcgcgat	Protospacer
************************

4. spacer 7.8|7059177|24|NZ_LN881739|CRT matches to position: 7059783-7059806, mismatch: 0, identity: 1.0

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggcttccgtcgcgat	Protospacer
************************

5. spacer 7.11|7059315|24|NZ_LN881739|CRT matches to position: 7059783-7059806, mismatch: 0, identity: 1.0

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggcttccgtcgcgat	Protospacer
************************

6. spacer 3.1|1844794|20|NZ_LN881739|CRISPRCasFinder matches to position: 7520163-7520182, mismatch: 1, identity: 0.95

acgagcccggggcgggcggc	CRISPR spacer
acgagctcggggcgggcggc	Protospacer
******.*************

7. spacer 7.1|7058871|24|NZ_LN881739|CRT matches to position: 7059357-7059380, mismatch: 1, identity: 0.958

accggtggtggcttccgtcgtgac	CRISPR spacer
accggtggtggcttccgccgtgac	Protospacer
*****************.******

8. spacer 7.1|7058871|24|NZ_LN881739|CRT matches to position: 7059510-7059533, mismatch: 1, identity: 0.958

accggtggtggcttccgtcgtgac	CRISPR spacer
accggtggtggcttccgccgtgac	Protospacer
*****************.******

9. spacer 7.3|7058955|24|NZ_LN881739|CRT matches to position: 7059783-7059806, mismatch: 1, identity: 0.958

tccggcggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggcttccgtcgcgat	Protospacer
*****.******************

10. spacer 3.1|1844794|20|NZ_LN881739|CRISPRCasFinder matches to position: 5367237-5367256, mismatch: 2, identity: 0.9

acgagcccggggcgggcggc	CRISPR spacer
acgagccgggcgcgggcggc	Protospacer
******* ** *********

11. spacer 3.1|1844794|20|NZ_LN881739|CRISPRCasFinder matches to position: 7124065-7124084, mismatch: 2, identity: 0.9

acgagcccggggcgggcggc	CRISPR spacer
acgagccggtggcgggcggc	Protospacer
******* * **********

12. spacer 3.1|1844794|20|NZ_LN881739|CRISPRCasFinder matches to position: 8235069-8235088, mismatch: 2, identity: 0.9

acgagcccggggcgggcggc	CRISPR spacer
acgagggcggggcgggcggc	Protospacer
*****  *************

13. spacer 3.1|1844794|20|NZ_LN881739|CRISPRCasFinder matches to position: 8276921-8276940, mismatch: 2, identity: 0.9

acgagcccggggcgggcggc	CRISPR spacer
acgagcccgatgcgggcggc	Protospacer
*********. *********

14. spacer 3.1|1844794|20|NZ_LN881739|CRISPRCasFinder matches to position: 5739593-5739612, mismatch: 2, identity: 0.9

acgagcccggggcgggcggc	CRISPR spacer
acgaggccgcggcgggcggc	Protospacer
***** *** **********

15. spacer 7.2|7058913|24|NZ_LN881739|CRT matches to position: 7059468-7059491, mismatch: 2, identity: 0.917

tccggcggtggcttccgtcgggac	CRISPR spacer
tccggcggtgggttccgtcgtgac	Protospacer
*********** ******** ***

16. spacer 7.5|7059042|33|NZ_LN881739|CRT matches to position: 7059936-7059968, mismatch: 2, identity: 0.939

ggtggtggcttccgtcgtgacgaccgtcgtgac	CRISPR spacer
ggtggcggcttccgtcgtgacgagcgtcgtgac	Protospacer
*****.***************** *********

17. spacer 7.6|7059093|24|NZ_LN881739|CRT matches to position: 7059741-7059764, mismatch: 2, identity: 0.917

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggcttccgccgtgat	Protospacer
*****************.**.***

18. spacer 7.7|7059135|24|NZ_LN881739|CRT matches to position: 7059468-7059491, mismatch: 2, identity: 0.917

tccggtggtggcttccgtcgtgac	CRISPR spacer
tccggcggtgggttccgtcgtgac	Protospacer
*****.***** ************

19. spacer 7.8|7059177|24|NZ_LN881739|CRT matches to position: 7059741-7059764, mismatch: 2, identity: 0.917

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggcttccgccgtgat	Protospacer
*****************.**.***

20. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to position: 7059468-7059491, mismatch: 2, identity: 0.917

tccggcggcggtttccgtcgtgac	CRISPR spacer
tccggcggtgggttccgtcgtgac	Protospacer
********.** ************

21. spacer 7.11|7059315|24|NZ_LN881739|CRT matches to position: 7059741-7059764, mismatch: 2, identity: 0.917

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggcttccgccgtgat	Protospacer
*****************.**.***

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LN881739_7	7.2\|7058913\|24\|NZ_LN881739\|CRT	7058913-7058936	24	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133638-133661	2	0.917
NZ_LN881739_7	7.3\|7058955\|24\|NZ_LN881739\|CRT	7058955-7058978	24	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133638-133661	2	0.917
NZ_LN881739_7	7.3\|7058955\|24\|NZ_LN881739\|CRT	7058955-7058978	24	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	803527-803550	2	0.917
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	311307-311330	2	0.917
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133605-133628	2	0.917
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133605-133631	3	0.889
NZ_LN881739_7	7.6\|7059093\|24\|NZ_LN881739\|CRT	7059093-7059116	24	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133638-133661	3	0.875
NZ_LN881739_7	7.6\|7059093\|24\|NZ_LN881739\|CRT	7059093-7059116	24	NZ_CP010616	Phaeobacter inhibens strain P92 plasmid pP92_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.6\|7059093\|24\|NZ_LN881739\|CRT	7059093-7059116	24	NZ_CP010635	Phaeobacter inhibens strain P78 plasmid pP78_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.6\|7059093\|24\|NZ_LN881739\|CRT	7059093-7059116	24	NZ_CP010755	Phaeobacter inhibens strain P70 plasmid pP70_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.6\|7059093\|24\|NZ_LN881739\|CRT	7059093-7059116	24	NZ_CP010713	Phaeobacter inhibens strain P66 plasmid pP66_h, complete sequence	8833-8856	3	0.875
NZ_LN881739_7	7.6\|7059093\|24\|NZ_LN881739\|CRT	7059093-7059116	24	NZ_CP010740	Phaeobacter inhibens strain P72 plasmid pP72_e, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.7\|7059135\|24\|NZ_LN881739\|CRT	7059135-7059158	24	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	1894078-1894101	3	0.875
NZ_LN881739_7	7.8\|7059177\|24\|NZ_LN881739\|CRT	7059177-7059200	24	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133638-133661	3	0.875
NZ_LN881739_7	7.8\|7059177\|24\|NZ_LN881739\|CRT	7059177-7059200	24	NZ_CP010616	Phaeobacter inhibens strain P92 plasmid pP92_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.8\|7059177\|24\|NZ_LN881739\|CRT	7059177-7059200	24	NZ_CP010635	Phaeobacter inhibens strain P78 plasmid pP78_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.8\|7059177\|24\|NZ_LN881739\|CRT	7059177-7059200	24	NZ_CP010755	Phaeobacter inhibens strain P70 plasmid pP70_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.8\|7059177\|24\|NZ_LN881739\|CRT	7059177-7059200	24	NZ_CP010713	Phaeobacter inhibens strain P66 plasmid pP66_h, complete sequence	8833-8856	3	0.875
NZ_LN881739_7	7.8\|7059177\|24\|NZ_LN881739\|CRT	7059177-7059200	24	NZ_CP010740	Phaeobacter inhibens strain P72 plasmid pP72_e, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	272280-272303	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_LR134462	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 20, complete sequence	28330-28353	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	361847-361870	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	391053-391076	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP021830	Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence	1317638-1317661	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	271420-271443	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	354298-354321	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	1561940-1561963	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	287286-287309	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	MK937606	Microbacterium phage Margaery, complete genome	16284-16307	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP021796	Sinorhizobium meliloti strain USDA1157 plasmid accessoryA, complete sequence	236826-236849	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	271126-271149	3	0.875
NZ_LN881739_7	7.9\|7059219\|24\|NZ_LN881739\|CRT	7059219-7059242	24	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	141738-141761	3	0.875
NZ_LN881739_7	7.11\|7059315\|24\|NZ_LN881739\|CRT	7059315-7059338	24	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	133638-133661	3	0.875
NZ_LN881739_7	7.11\|7059315\|24\|NZ_LN881739\|CRT	7059315-7059338	24	NZ_CP010616	Phaeobacter inhibens strain P92 plasmid pP92_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.11\|7059315\|24\|NZ_LN881739\|CRT	7059315-7059338	24	NZ_CP010635	Phaeobacter inhibens strain P78 plasmid pP78_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.11\|7059315\|24\|NZ_LN881739\|CRT	7059315-7059338	24	NZ_CP010755	Phaeobacter inhibens strain P70 plasmid pP70_f, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.11\|7059315\|24\|NZ_LN881739\|CRT	7059315-7059338	24	NZ_CP010713	Phaeobacter inhibens strain P66 plasmid pP66_h, complete sequence	8833-8856	3	0.875
NZ_LN881739_7	7.11\|7059315\|24\|NZ_LN881739\|CRT	7059315-7059338	24	NZ_CP010740	Phaeobacter inhibens strain P72 plasmid pP72_e, complete sequence	8834-8857	3	0.875
NZ_LN881739_7	7.2\|7058913\|24\|NZ_LN881739\|CRT	7058913-7058936	24	NZ_CP039696	Novosphingobium sp. ABRDHK2 plasmid pABRDHK21, complete sequence	43993-44016	4	0.833
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP032928	Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence	156812-156838	5	0.815
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	797755-797781	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	272277-272303	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_LR134462	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 20, complete sequence	28327-28353	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	27081-27107	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	361844-361870	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	391050-391076	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	311304-311330	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP021830	Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence	1317635-1317661	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	271417-271443	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	354295-354321	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	1561937-1561963	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	287283-287309	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	800731-800757	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP034473	Pantoea agglomerans strain CFSAN047153 plasmid pCFSAN047153_4, complete sequence	32761-32787	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP034478	Pantoea agglomerans strain CFSAN047154 plasmid pCFSAN047154_4, complete sequence	76361-76387	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP021796	Sinorhizobium meliloti strain USDA1157 plasmid accessoryA, complete sequence	236826-236852	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	271126-271152	6	0.778
NZ_LN881739_7	7.4\|7058997\|27\|NZ_LN881739\|CRT	7058997-7059023	27	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	141738-141764	6	0.778
NZ_LN881739_2	2.2\|1652835\|31\|NZ_LN881739\|CRISPRCasFinder	1652835-1652865	31	NZ_CP006372	Aureimonas sp. AU20 plasmid pAU20e, complete sequence	11290-11320	8	0.742
NZ_LN881739_3	3.4\|1844945\|35\|NZ_LN881739\|CRISPRCasFinder	1844945-1844979	35	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	1998931-1998965	9	0.743

1. spacer 7.2|7058913|24|NZ_LN881739|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 2, identity: 0.917

tccggcggtggcttccgtcgggac	CRISPR spacer
tccggcggtggcttccgccgcgac	Protospacer
*****************.** ***

2. spacer 7.3|7058955|24|NZ_LN881739|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 2, identity: 0.917

tccggcggtggcttccgtcgcgat	CRISPR spacer
tccggcggtggcttccgccgcgac	Protospacer
*****************.*****.

3. spacer 7.3|7058955|24|NZ_LN881739|CRT matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.917

tccggcggtggcttccgtcgcgat	CRISPR spacer
ttcggctgtggcttccgtcgcgat	Protospacer
*.**** *****************

4. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 2, identity: 0.917

tccggcggcggtttccgtcgtgac	CRISPR spacer
tccggcggcggtttccgacttgac	Protospacer
***************** * ****

5. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 2, identity: 0.917

tccggcggcggtttccgtcgtgac	CRISPR spacer
tcgggcggcggtttccgccgtgac	Protospacer
** **************.******

6. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 3, identity: 0.889

accggcggcggtttccgtcgtgacgac	CRISPR spacer
tcgggcggcggtttccgccgtgacgac	Protospacer
 * **************.*********

7. spacer 7.6|7059093|24|NZ_LN881739|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggcggtggcttccgccgcgac	Protospacer
*****.***********.*****.

8. spacer 7.6|7059093|24|NZ_LN881739|CRT matches to NZ_CP010616 (Phaeobacter inhibens strain P92 plasmid pP92_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

9. spacer 7.6|7059093|24|NZ_LN881739|CRT matches to NZ_CP010635 (Phaeobacter inhibens strain P78 plasmid pP78_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

10. spacer 7.6|7059093|24|NZ_LN881739|CRT matches to NZ_CP010755 (Phaeobacter inhibens strain P70 plasmid pP70_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

11. spacer 7.6|7059093|24|NZ_LN881739|CRT matches to NZ_CP010713 (Phaeobacter inhibens strain P66 plasmid pP66_h, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

12. spacer 7.6|7059093|24|NZ_LN881739|CRT matches to NZ_CP010740 (Phaeobacter inhibens strain P72 plasmid pP72_e, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

13. spacer 7.7|7059135|24|NZ_LN881739|CRT matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgtgac	CRISPR spacer
tctggtgatggcttccgtcgtgat	Protospacer
**.****.***************.

14. spacer 7.8|7059177|24|NZ_LN881739|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggcggtggcttccgccgcgac	Protospacer
*****.***********.*****.

15. spacer 7.8|7059177|24|NZ_LN881739|CRT matches to NZ_CP010616 (Phaeobacter inhibens strain P92 plasmid pP92_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

16. spacer 7.8|7059177|24|NZ_LN881739|CRT matches to NZ_CP010635 (Phaeobacter inhibens strain P78 plasmid pP78_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

17. spacer 7.8|7059177|24|NZ_LN881739|CRT matches to NZ_CP010755 (Phaeobacter inhibens strain P70 plasmid pP70_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

18. spacer 7.8|7059177|24|NZ_LN881739|CRT matches to NZ_CP010713 (Phaeobacter inhibens strain P66 plasmid pP66_h, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

19. spacer 7.8|7059177|24|NZ_LN881739|CRT matches to NZ_CP010740 (Phaeobacter inhibens strain P72 plasmid pP72_e, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

20. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

21. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_LR134462 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 20, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
gccggcgtcggtgtccgtcgtgac	Protospacer
 ****** **** ***********

22. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

23. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

24. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP021830 (Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

25. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

26. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

27. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

28. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

29. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to MK937606 (Microbacterium phage Margaery, complete genome) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
tccggcggcggtttccgtctcgtc	Protospacer
******************* .* *

30. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP021796 (Sinorhizobium meliloti strain USDA1157 plasmid accessoryA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

31. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

32. spacer 7.9|7059219|24|NZ_LN881739|CRT matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 3, identity: 0.875

tccggcggcggtttccgtcgtgac	CRISPR spacer
cccggcggcggtttccgacttgac	Protospacer
.**************** * ****

33. spacer 7.11|7059315|24|NZ_LN881739|CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggcggtggcttccgccgcgac	Protospacer
*****.***********.*****.

34. spacer 7.11|7059315|24|NZ_LN881739|CRT matches to NZ_CP010616 (Phaeobacter inhibens strain P92 plasmid pP92_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

35. spacer 7.11|7059315|24|NZ_LN881739|CRT matches to NZ_CP010635 (Phaeobacter inhibens strain P78 plasmid pP78_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

36. spacer 7.11|7059315|24|NZ_LN881739|CRT matches to NZ_CP010755 (Phaeobacter inhibens strain P70 plasmid pP70_f, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

37. spacer 7.11|7059315|24|NZ_LN881739|CRT matches to NZ_CP010713 (Phaeobacter inhibens strain P66 plasmid pP66_h, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

38. spacer 7.11|7059315|24|NZ_LN881739|CRT matches to NZ_CP010740 (Phaeobacter inhibens strain P72 plasmid pP72_e, complete sequence) position: , mismatch: 3, identity: 0.875

tccggtggtggcttccgtcgcgat	CRISPR spacer
tccggtggtggctgccgtcgcaac	Protospacer
************* *******.*.

39. spacer 7.2|7058913|24|NZ_LN881739|CRT matches to NZ_CP039696 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK21, complete sequence) position: , mismatch: 4, identity: 0.833

tccggcggtggcttccgtcgggac	CRISPR spacer
gtcggcggtggcttcggtcgggat	Protospacer
 .************* *******.

40. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP032928 (Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence) position: , mismatch: 5, identity: 0.815

accggcggcggtttccgtcgtgacgac	CRISPR spacer
ggctgcggcggtttccgtcgtggcggc	Protospacer
. * ******************.**.*

41. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
gtgcgcggcggtttccgccgtgacgag	Protospacer
..  *************.********

42. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

43. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_LR134462 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 20, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
gccggcgtcggtgtccgtcgtgaccta	Protospacer
.****** **** ***********

44. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cggggcggcggtctgcgtcgtgacgag	Protospacer
   *********.* ***********

45. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

46. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

47. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
tccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

48. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP021830 (Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

49. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

50. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

51. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

52. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

53. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cggggcggcggtctgcgtcgtgacgag	Protospacer
   *********.* ***********

54. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP034473 (Pantoea agglomerans strain CFSAN047153 plasmid pCFSAN047153_4, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
ttcggcggcggtttccgccgttacgtg	Protospacer
 .***************.*** ***

55. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP034478 (Pantoea agglomerans strain CFSAN047154 plasmid pCFSAN047154_4, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
ttcggcggcggtttccgccgttacgtg	Protospacer
 .***************.*** ***

56. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP021796 (Sinorhizobium meliloti strain USDA1157 plasmid accessoryA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

57. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

58. spacer 7.4|7058997|27|NZ_LN881739|CRT matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 6, identity: 0.778

accggcggcggtttccgtcgtgacgac	CRISPR spacer
cccggcggcggtttccgacttgaccca	Protospacer
 **************** * ****

59. spacer 2.2|1652835|31|NZ_LN881739|CRISPRCasFinder matches to NZ_CP006372 (Aureimonas sp. AU20 plasmid pAU20e, complete sequence) position: , mismatch: 8, identity: 0.742

tcgtccgggtacgccggaggcgcgggctcgt	CRISPR spacer
caatccgcgcacgccggaggcgcgggccagc	Protospacer
. .**** *.*****************. *.

60. spacer 3.4|1844945|35|NZ_LN881739|CRISPRCasFinder matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 9, identity: 0.743

ctcagctggagctccgcccggacggagcagtcaga	CRISPR spacer
ccaatagggagctccgcccgggcggagctgtctgc	Protospacer
*. *   **************.****** *** *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

63871 : 94457

Bacillus_phage(100.0%)

tail,protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_055645732.1\|63871_65491_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_055639264.1\|65665_66625_-\|transposase	transposase	S6AND0	Bacillus_phage	8.2e-18	30.4
WP_055639265.1\|66712_67147_+	hypothetical protein	NA	NA	NA	NA
WP_055639267.1\|68313_68544_-	hypothetical protein	NA	NA	NA	NA
WP_055639269.1\|69043_69370_-	hypothetical protein	NA	NA	NA	NA
WP_152335164.1\|69908_70640_-	hypothetical protein	NA	NA	NA	NA
WP_055639271.1\|71145_71589_+	hypothetical protein	NA	NA	NA	NA
WP_055639273.1\|72103_72445_+	hypothetical protein	NA	NA	NA	NA
WP_079037825.1\|72748_73429_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_055639275.1\|73449_74349_-	phosphotransferase	NA	NA	NA	NA
WP_055639276.1\|74508_75183_-	hypothetical protein	NA	NA	NA	NA
WP_057950582.1\|75363_75741_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_099054494.1\|76480_76882_-\|tail	lamin tail domain-containing protein	NA	NA	NA	NA
WP_055639279.1\|77961_78507_+	hypothetical protein	NA	NA	NA	NA
WP_055639280.1\|78830_79019_+	hypothetical protein	NA	NA	NA	NA
WP_055639281.1\|79140_79656_-	NUDIX hydrolase	NA	NA	NA	NA
WP_055639282.1\|79717_80371_-	hypothetical protein	NA	NA	NA	NA
WP_079037826.1\|80367_80988_-	hypothetical protein	NA	NA	NA	NA
WP_055639283.1\|81342_81531_+	hypothetical protein	NA	NA	NA	NA
WP_055639284.1\|81953_82328_+	hypothetical protein	NA	NA	NA	NA
WP_107105457.1\|82760_83429_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_055639288.1\|84166_84736_-	hypothetical protein	NA	NA	NA	NA
WP_079037187.1\|84735_85263_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_055639290.1\|86204_86456_+	hypothetical protein	NA	NA	NA	NA
WP_055639291.1\|86422_86941_-	hypothetical protein	NA	NA	NA	NA
WP_152335165.1\|87099_88119_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_055639293.1\|88925_89618_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_055639294.1\|89618_90530_-	phosphotransferase	NA	NA	NA	NA
WP_055639295.1\|90609_91356_-	hypothetical protein	NA	NA	NA	NA
WP_152335166.1\|93469_93928_-	hypothetical protein	NA	NA	NA	NA
WP_107105456.1\|94190_94457_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_2

517970 : 555717

Bacillus_phage(33.33%)

plate,tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_055639578.1\|517970_519551_+\|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	4.2e-67	34.0
WP_024754772.1\|519632_520076_+\|tail	phage tail protein	NA	NA	NA	NA
WP_055639579.1\|520075_520495_+	hypothetical protein	NA	NA	NA	NA
WP_152335187.1\|521296_522103_-	hypothetical protein	NA	NA	NA	NA
WP_152335188.1\|522808_523438_-	hypothetical protein	NA	NA	NA	NA
WP_057950608.1\|523507_523693_+	hypothetical protein	NA	NA	NA	NA
WP_055639582.1\|523764_524202_+\|tail	phage tail protein	NA	NA	NA	NA
WP_055639583.1\|524203_524944_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_055639584.1\|524940_526758_+	VgrG-related protein	NA	NA	NA	NA
WP_024759521.1\|526771_527170_+	GPW/gp25 family protein	A0A0E3FHN9	Synechococcus_phage	2.0e-10	38.5
WP_055639585.1\|527181_529170_+\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_055639586.1\|529166_529736_+\|tail	phage tail protein	NA	NA	NA	NA
WP_055639587.1\|529740_530910_+	hypothetical protein	NA	NA	NA	NA
WP_079037233.1\|533213_534437_-	hypothetical protein	NA	NA	NA	NA
WP_055639588.1\|534731_535232_+	thiol peroxidase	NA	NA	NA	NA
WP_055639589.1\|535306_535717_-	transcriptional repressor	NA	NA	NA	NA
WP_055639590.1\|535924_538144_+	catalase/peroxidase HPI	NA	NA	NA	NA
WP_055639591.1\|538229_539423_-	ABC transporter permease	NA	NA	NA	NA
WP_055639592.1\|539419_540124_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.1e-30	39.3
WP_055639593.1\|540120_541200_-	peptidoglycan-binding protein	NA	NA	NA	NA
WP_055639594.1\|541196_541868_-	hypothetical protein	NA	NA	NA	NA
WP_055639595.1\|542002_542698_+	response regulator transcription factor	W8CYM9	Bacillus_phage	6.1e-31	33.3
WP_055645786.1\|542763_544266_+	HAMP domain-containing histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	6.6e-06	24.7
WP_055639596.1\|544262_544760_+	hypothetical protein	NA	NA	NA	NA
WP_055639597.1\|544813_545680_-	acetylxylan esterase	NA	NA	NA	NA
WP_055639598.1\|545937_546936_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_055639599.1\|547050_548007_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_079037846.1\|548407_549517_+	serine hydrolase	G1BNF7	Mycobacterium_phage	6.6e-19	26.6
WP_055639600.1\|549541_550075_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_055639601.1\|550393_551230_-	class II fructose-bisphosphate aldolase family protein	NA	NA	NA	NA
WP_055639603.1\|551644_552448_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_055639605.1\|553692_555717_+\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA

DBSCAN-SWA_3

3776587 : 3791745

Streptomyces_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_055641858.1\|3776587_3777784_+	hypothetical protein	A0A2H5BLD9	Streptomyces_phage	1.4e-35	43.8
WP_055641860.1\|3779162_3780299_+	hypothetical protein	A0A2H5BLD9	Streptomyces_phage	2.9e-38	31.7
WP_055641861.1\|3780311_3781412_+	hypothetical protein	A0A1J0MCX4	Streptomyces_phage	1.9e-87	46.7
WP_055641862.1\|3781411_3782122_+	hypothetical protein	NA	NA	NA	NA
WP_055641863.1\|3782721_3783645_+	N-acetylmuramoyl-L-alanine amidase	A0A2P1N078	Streptomyces_phage	4.0e-102	59.2
WP_055641864.1\|3783688_3783922_+	hypothetical protein	A0A142K647	Streptomyces_phage	9.5e-21	79.4
WP_055641865.1\|3783908_3784172_+	hypothetical protein	A0A1J0MCA5	Streptomyces_phage	5.1e-31	80.5
WP_024755375.1\|3784244_3788159_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	5.9e-54	27.2
WP_055641866.1\|3788262_3791745_-	DNA-directed RNA polymerase subunit beta	G8DH04	Emiliania_huxleyi_virus	4.0e-30	22.2

DBSCAN-SWA_4

8897756 : 8965750

Mycobacterium_phage(100.0%)

tail,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152335303.1\|8897756_8898203_-\|transposase	transposase	NA	NA	NA	NA
WP_063785808.1\|8898285_8898630_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_055645637.1\|8899787_8900423_-	VOC family protein	NA	NA	NA	NA
WP_055645639.1\|8901634_8902450_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_055645640.1\|8903534_8903960_+	hypothetical protein	NA	NA	NA	NA
WP_055645641.1\|8904637_8904916_+	hypothetical protein	NA	NA	NA	NA
WP_152335304.1\|8904917_8905367_+	hypothetical protein	NA	NA	NA	NA
WP_152335305.1\|8906218_8906410_+	hypothetical protein	NA	NA	NA	NA
WP_055645644.1\|8906503_8908729_-	VCBS repeat-containing protein	NA	NA	NA	NA
WP_099054240.1\|8909147_8909660_+	hypothetical protein	NA	NA	NA	NA
WP_055646593.1\|8910621_8911050_+	hypothetical protein	NA	NA	NA	NA
WP_055645646.1\|8911398_8912157_+	hypothetical protein	NA	NA	NA	NA
WP_055645648.1\|8913267_8914857_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	1.7e-31	31.6
WP_055645649.1\|8916346_8916721_+	hypothetical protein	NA	NA	NA	NA
WP_055645651.1\|8917073_8917415_+	HopJ type III effector protein	NA	NA	NA	NA
WP_099054388.1\|8918654_8919572_-	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_152335306.1\|8920697_8921942_-	hypothetical protein	NA	NA	NA	NA
WP_152335307.1\|8921952_8922318_-	hypothetical protein	NA	NA	NA	NA
WP_152335308.1\|8922314_8923148_-\|transposase	transposase	NA	NA	NA	NA
WP_055645656.1\|8923222_8924164_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_055645657.1\|8924235_8925162_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_055645658.1\|8925339_8925981_+	hypothetical protein	NA	NA	NA	NA
WP_055645659.1\|8926116_8926791_-	response regulator transcription factor	NA	NA	NA	NA
WP_055645660.1\|8926787_8928065_-	sensor histidine kinase	NA	NA	NA	NA
WP_079037815.1\|8930332_8931766_+	hypothetical protein	NA	NA	NA	NA
WP_055645663.1\|8931762_8932422_+	response regulator transcription factor	NA	NA	NA	NA
WP_055645664.1\|8933808_8934414_+	deaminase	NA	NA	NA	NA
WP_099054239.1\|8935671_8936148_+	SRPBCC family protein	NA	NA	NA	NA
WP_079037816.1\|8936273_8937086_-	universal stress protein	NA	NA	NA	NA
WP_079037817.1\|8937316_8937514_-	hypothetical protein	NA	NA	NA	NA
WP_055645667.1\|8937931_8938135_+	EF-hand domain-containing protein	NA	NA	NA	NA
WP_055645668.1\|8938865_8939984_-	acyl-CoA desaturase	NA	NA	NA	NA
WP_055645669.1\|8939991_8941047_-	ferredoxin reductase	NA	NA	NA	NA
WP_055645670.1\|8941133_8942273_+	PucR family transcriptional regulator	NA	NA	NA	NA
WP_055645671.1\|8942302_8943016_+	hypothetical protein	NA	NA	NA	NA
WP_152335309.1\|8943330_8944254_+	hypothetical protein	NA	NA	NA	NA
WP_063785811.1\|8944254_8944611_+	hypothetical protein	NA	NA	NA	NA
WP_152335310.1\|8944645_8944867_+	hypothetical protein	NA	NA	NA	NA
WP_055645672.1\|8945259_8945457_-	hypothetical protein	NA	NA	NA	NA
WP_055645673.1\|8946162_8946717_+	TerB family tellurite resistance protein	NA	NA	NA	NA
WP_055645675.1\|8947395_8947989_-	hypothetical protein	NA	NA	NA	NA
WP_107105409.1\|8948799_8949675_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_152335311.1\|8950254_8950473_-	hypothetical protein	NA	NA	NA	NA
WP_055645678.1\|8951459_8951900_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_055645679.1\|8952046_8953540_+	MFS transporter	NA	NA	NA	NA
WP_107105408.1\|8953719_8954040_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_055646595.1\|8954143_8954593_-	hypothetical protein	NA	NA	NA	NA
WP_055645680.1\|8954718_8955009_-	hypothetical protein	NA	NA	NA	NA
WP_055645681.1\|8956283_8956961_-	oxygenase	NA	NA	NA	NA
WP_055645683.1\|8957343_8957883_-	hypothetical protein	NA	NA	NA	NA
WP_152335312.1\|8958600_8958801_-\|transposase	transposase	NA	NA	NA	NA
WP_055645684.1\|8959110_8959737_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_055645685.1\|8959989_8960337_+	glyoxalase	NA	NA	NA	NA
WP_152335313.1\|8960640_8961408_-	hypothetical protein	NA	NA	NA	NA
WP_055645687.1\|8961572_8961827_+	hypothetical protein	NA	NA	NA	NA
WP_079037819.1\|8962505_8962871_-	DCL family protein	NA	NA	NA	NA
WP_055645690.1\|8963747_8964473_-	hypothetical protein	NA	NA	NA	NA
WP_055645691.1\|8964520_8964781_-	hypothetical protein	NA	NA	NA	NA
WP_099054386.1\|8965348_8965750_+\|tail	lamin tail domain-containing protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LN881739

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection