CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP008717	Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis plasmid pEC648_3, complete sequence	0 crisprs	NA	0	0	0
NZ_CP008718	Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis plasmid pEC648_4, complete sequence	0 crisprs	NA	0	0	0
NZ_CP008715	Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis plasmid pEC648_1, complete sequence	0 crisprs	csa3	0	0	1
NZ_CP008721	Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis plasmid pEC648_7, complete sequence	0 crisprs	NA	0	0	0
NZ_CP008719	Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis plasmid pEC648_5, complete sequence	0 crisprs	NA	0	0	0
NZ_CP008697	Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis chromosome, complete genome	4 crisprs	DEDDh,DinG,cas3,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,RT,WYL,PD-DExK	2	21	11
NZ_CP008716	Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis plasmid pEC648_2, complete sequence	0 crisprs	NA	0	0	0
NZ_CP008720	Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis plasmid pEC648_6, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

13084 : 85948

Escherichia_phage(33.33%)

integrase,transposase

attL 27334:27393|attR 76433:76588

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000016982.1\|13084_13891_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.8e-57	100.0
WP_060684530.1\|13891_14197_-	type II toxin-antitoxin system toxin CcdB	NA	NA	NA	NA
WP_000813634.1\|14198_14417_-	type II toxin-antitoxin system antitoxin CcdA	NA	NA	NA	NA
WP_000151784.1\|14983_15496_+	hypothetical protein	NA	NA	NA	NA
WP_001542067.1\|15529_16663_-	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_000528931.1\|17616_18117_-	hypothetical protein	NA	NA	NA	NA
WP_001261278.1\|18381_18612_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_001034046.1\|18608_19025_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_001261286.1\|23245_23476_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_001034044.1\|23472_23889_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_001128474.1\|23963_25529_+	AAA family ATPase	NA	NA	NA	NA
27334:27393	attL	NA	NA	NA	NA
WP_000949004.1\|27789_28704_+	iron/manganese ABC transporter substrate-binding protein SitA	NA	NA	NA	NA
WP_000983710.1\|28703_29531_+	iron/manganese ABC transporter ATP-binding protein SitB	A0A1M7XV31	Cedratvirus	3.6e-14	27.0
WP_001101723.1\|29527_30385_+	iron/manganese ABC transporter permease subunit SitC	NA	NA	NA	NA
WP_000968139.1\|30381_31239_+	iron/manganese ABC transporter permease subunit SitD	NA	NA	NA	NA
WP_001318207.1\|32481_32862_+	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	1.9e-26	55.0
WP_000095526.1\|33241_34435_-	MFS transporter	NA	NA	NA	NA
WP_000602863.1\|34570_36295_+	aerobactin synthase IucA	NA	NA	NA	NA
WP_000011908.1\|36295_37243_+	N(6)-hydroxylysine O-acetyltransferase	NA	NA	NA	NA
WP_001015721.1\|37242_38985_+	aerobactin synthase IucC	NA	NA	NA	NA
WP_000750130.1\|38981_40259_+	NADPH-dependent L-lysine N(6)-monooxygenase	NA	NA	NA	NA
WP_000973519.1\|40340_42542_+	ferric aerobactin receptor IutA	NA	NA	NA	NA
WP_000361611.1\|45547_46525_+	replication initiation protein	J9Q7H0	Salmonella_phage	4.6e-101	63.9
WP_060684531.1\|46809_47550_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	2.0e-24	57.6
WP_042344623.1\|47670_47853_-	hypothetical protein	NA	NA	NA	NA
WP_001105060.1\|50361_50655_-	hypothetical protein	NA	NA	NA	NA
WP_000421272.1\|50760_51036_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_001387467.1\|51035_51320_-	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_000562172.1\|51924_52677_+	IclR family transcriptional regulator	NA	NA	NA	NA
WP_024946717.1\|53707_54088_-	endoribonuclease	NA	NA	NA	NA
WP_001077068.1\|54112_55003_-	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_000796505.1\|55235_55430_-	hypothetical protein	NA	NA	NA	NA
WP_000338039.1\|55974_56853_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_001271561.1\|56842_57730_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_000922702.1\|57740_58565_+	phosphodiesterase	NA	NA	NA	NA
WP_000950177.1\|58570_59644_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.6e-28	33.7
WP_000476108.1\|59636_60947_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001067834.1\|62866_63571_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	3.1e-139	99.6
WP_000205718.1\|67231_67978_+	conjugal transfer pilus acetylase TraX	A0A077JBM8	Xanthomonas_phage	3.2e-09	30.9
WP_000139341.1\|68032_68593_+	fertility inhibition protein FinO	NA	NA	NA	NA
WP_013023861.1\|68724_68937_+	hypothetical protein	NA	NA	NA	NA
WP_023144756.1\|69807_69942_+	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_001323403.1\|70417_71197_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-139	100.0
WP_000255944.1\|71196_72219_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_072258247.1\|72299_72452_+	replication protein A	NA	NA	NA	NA
WP_031943482.1\|72688_72763_+	RepA leader peptide Tap	NA	NA	NA	NA
WP_000130640.1\|72755_73613_+	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_000557619.1\|75263_75521_+	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_001398199.1\|75453_75855_+	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_060684534.1\|77683_78241_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.6e-93	99.5
76433:76588	attR	NA	NA	NA	NA
WP_001067855.1\|78564_79269_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001389366.1\|80171_80645_+	trimethoprim-resistant dihydrofolate reductase DfrA17	A0A1B2IAU3	Erwinia_phage	1.3e-16	34.6
WP_000503573.1\|80775_81564_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5	NA	NA	NA	NA
WP_000679427.1\|81769_82117_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|82110_82950_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000376616.1\|83077_83281_+	hypothetical protein	NA	NA	NA	NA
WP_000184001.1\|83436_84642_+	chromate efflux transporter	NA	NA	NA	NA
WP_001389365.1\|85183_85948_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP008697

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP008697_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008697_1

1755007-1755154

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGTACAGGCAGCTTAGAAA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP008697_1

>merge|NZ_CP008697|1|1755007-1755154|CRISPRCasFinder
GTTCACTGCCGTACAGGCAGCTTAGAAAGGAACAATCTTGCAAAGGCTGTGAAAGTTGGCGTTCACTGCCGTACAGGCAGCTTAGAAATTCACTGGTAACATACTCCACCCGCCCACCATGTTCACTGCCGTACAGGCAGATAAAATG

>NZ_CP008697|1|1|1755007-1755154|CRISPRCasFinder
GTTCACTGCCGTACAGGCAGCTTAGAAA	GGAACAATCTTGCAAAGGCTGTGAAAGTTGGC
GTTCACTGCCGTACAGGCAGCTTAGAAA	TTCACTGGTAACATACTCCACCCGCCCACCAT
GTTCACTGCCGTACAGGCAGATAAAATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008697.1\|WP_001400542.1\|1747378_1748335_-\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
NZ_CP008697.1\|WP_001295343.1\|1766766_1767378_+\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NZ_CP008697.1\|WP_001043590.1\|1758510_1760277_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NZ_CP008697.1\|WP_000228473.1\|1761908_1762403_+\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009
NZ_CP008697.1\|WP_001040187.1\|1755539_1755758_-\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NZ_CP008697.1\|WP_022645455.1\|1762537_1766608_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NZ_CP008697.1\|WP_000537432.1\|1760399_1761365_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NZ_CP008697.1\|WP_000178691.1\|1740470_1741439_-\|NADH-oxidoreductase	unknown	unknown	gnl\|CDD\|236735
NZ_CP008697.1\|WP_000520781.1\|1752163_1752484_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP008697.1\|WP_022645444.1\|1749597_1751544_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NZ_CP008697.1\|WP_022645440.1\|1741450_1743103_-\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NZ_CP008697.1\|WP_001202192.1\|1756788_1758510_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
NZ_CP008697.1\|WP_022645441.1\|1743245_1744145_-\|L-lysine-exporter-LysO	unknown	unknown	gnl\|CDD\|225287
NZ_CP008697.1\|WP_000746460.1\|1748485_1749601_+\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NZ_CP008697.1\|WP_060684407.1\|1767388_1768732_+\|replication-associated-recombination-protein-RarA	unknown	unknown	gnl\|CDD\|237355
NZ_CP008697.1\|WP_000599806.1\|1745723_1747382_+\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NZ_CP008697.1\|WP_000410785.1\|1751616_1751841_-\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
NZ_CP008697.1\|WP_022645453.1\|1756042_1756747_-\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NZ_CP008697.1\|WP_000886683.1\|1768822_1770115_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP008697.1\|WP_000488716.1\|1744602_1745298_-\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453

Protein	Function_ID	Function_description	E-value
NZ_CP008697.1\|WP_001400542.1\|1747378_1748335_-\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	1.4029e-131
NZ_CP008697.1\|WP_001295343.1\|1766766_1767378_+\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
NZ_CP008697.1\|WP_001043590.1\|1758510_1760277_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP008697.1\|WP_000228473.1\|1761908_1762403_+\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
NZ_CP008697.1\|WP_001040187.1\|1755539_1755758_-\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
NZ_CP008697.1\|WP_022645455.1\|1762537_1766608_+\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NZ_CP008697.1\|WP_000537432.1\|1760399_1761365_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NZ_CP008697.1\|WP_000178691.1\|1740470_1741439_-\|NADH-oxidoreductase	gnl\|CDD\|236735	PRK10684, PRK10684, HCP oxidoreductase, NADH-dependent; Provisional.	0
NZ_CP008697.1\|WP_000520781.1\|1752163_1752484_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
NZ_CP008697.1\|WP_022645444.1\|1749597_1751544_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NZ_CP008697.1\|WP_022645440.1\|1741450_1743103_-\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NZ_CP008697.1\|WP_001202192.1\|1756788_1758510_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP008697.1\|WP_022645441.1\|1743245_1744145_-\|L-lysine-exporter-LysO	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	2.06035e-116
NZ_CP008697.1\|WP_000746460.1\|1748485_1749601_+\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NZ_CP008697.1\|WP_060684407.1\|1767388_1768732_+\|replication-associated-recombination-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP008697.1\|WP_000599806.1\|1745723_1747382_+\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NZ_CP008697.1\|WP_000410785.1\|1751616_1751841_-\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
NZ_CP008697.1\|WP_022645453.1\|1756042_1756747_-\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.78168e-138
NZ_CP008697.1\|WP_000886683.1\|1768822_1770115_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP008697.1\|WP_000488716.1\|1744602_1745298_-\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	7.82992e-144

>NZ_CP008697.1|WP_000520781.1|1752163_1752484_+|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NZ_CP008697.1|WP_000410785.1|1751616_1751841_-|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>NZ_CP008697.1|WP_022645444.1|1749597_1751544_+|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVSNPPAIEKVNVAGGTEPVVNTASGWRQFASGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>NZ_CP008697.1|WP_000746460.1|1748485_1749601_+|macrolide-transporter-subunit-MacA
MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>NZ_CP008697.1|WP_001400542.1|1747378_1748335_-|DUF535-domain-containing-protein
MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG
>NZ_CP008697.1|WP_000599806.1|1745723_1747382_+|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>NZ_CP008697.1|WP_000488716.1|1744602_1745298_-|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRN
>NZ_CP008697.1|WP_022645441.1|1743245_1744145_-|L-lysine-exporter-LysO
MFSGLLIILVPLILGYLIPLRQKAALKVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNYHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>NZ_CP008697.1|WP_022645440.1|1741450_1743103_-|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIATLQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIVLREALKAQCLAVDANAHVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETSKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
>NZ_CP008697.1|WP_000178691.1|1740470_1741439_-|NADH-oxidoreductase
MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYALVSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSRWLTRDVKRGDYLWLSDAMGEFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVQVIYNVRTPQDVIFADEWRNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKALGVTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAGVCGCCKTKVVSGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLVLA
>NZ_CP008697.1|WP_001040187.1|1755539_1755758_-|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NZ_CP008697.1|WP_022645453.1|1756042_1756747_-|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWCEDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNKFWVPRCLFSPQE
>NZ_CP008697.1|WP_001202192.1|1756788_1758510_-|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEATLRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>NZ_CP008697.1|WP_001043590.1|1758510_1760277_-|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQTALDNAWVSEFLPLLPQGIDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGRYAELSVAGGPFATLLAHRQEEI
>NZ_CP008697.1|WP_000537432.1|1760399_1761365_-|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NZ_CP008697.1|WP_000228473.1|1761908_1762403_+|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NZ_CP008697.1|WP_022645455.1|1762537_1766608_+|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEEDESHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPTQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPVQQPYYAPAPEQSAQQPYYAPAPEQSVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSAGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFTLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPIAPQQQYQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NZ_CP008697.1|WP_001295343.1|1766766_1767378_+|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>NZ_CP008697.1|WP_060684407.1|1767388_1768732_+|replication-associated-recombination-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTKDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAITQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NZ_CP008697.1|WP_000886683.1|1768822_1770115_+|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG

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Crispr_ID: NZ_CP008697_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008697_2

3789324-3790147

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	PILER-CR

13 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP008697_2

>merge|NZ_CP008697|2|3789324-3790147|CRISPRCasFinder,CRT,PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACTCGCCGGAAAATATTCATGATGGGGGTGGTTATGGCGGTTTATCCCCGCTGGCGCGGGGAACTCGGGGCCGCCGTGTTCACATTTGCCTAATTTCCCGGTTTATCCCCGCTGGCGCGGGGAACTCAACATGTCTTTCGTCAATTTTGGCGCTATAAACGGTTTATCCCCGCTGGCGCGGGGAACTCTATATAAACGAGGTGAATTTATGGAAACTGTACGGTTTATCCCCGCTGGCGCGGGGAACTCGTTAGTTTTCTGAAAAAAATTGTTTTCTTACGCTGGTTTATCCCCGCTGGCGCGGGGAACTCAATATTGTCGTGGACAAATGCCGGTGTTATTGCGGTTTATCCCCGCTGGCGCGGGGAACTCTTCGAGACACTTCTCTGCAAAATTAATGAAATCGGTTTATCCCCGCTGGCGCGGGGAACTCCAGGTATCAAGAAATAATCGAAGCCTTCATGACGGTTTATCCCCGCTGGCGCGGGGAACTCAATTGATTGCTGGGTGATATTGGAAAATGTTGCGGTTTATCCCCGCTGGCGCGGGGAACTCTACCGTACAGACTGCCGGATATTATTTTTTTGCGGTTTATCCCCGCTGGCGCGGGGAACTCCGACGTTCGACGAAATGCGCGATGGCGGTCGGCGGTTTATCCCCGCTGGCGCGGGGAACTCTTCTGCGTCCCCGATGTCTGGCCCGACTGGTCCGGTTTATCCCCGCTGGCGCGGGGAACTCTATATGACCGGAACACTTCCGCCTGACGTTTGCGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP008697|2|2|3789324-3790147|CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCCGGAAAATATTCATGATGGGGGTGGTTATGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GGGGCCGCCGTGTTCACATTTGCCTAATTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AACATGTCTTTCGTCAATTTTGGCGCTATAAA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATAAACGAGGTGAATTTATGGAAACTGTA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GTTAGTTTTCTGAAAAAAATTGTTTTCTTACGC
TGGTTTATCCCCGCTGGCGCGGGGAACTC	AATATTGTCGTGGACAAATGCCGGTGTTATTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCGAGACACTTCTCTGCAAAATTAATGAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CAGGTATCAAGAAATAATCGAAGCCTTCATGA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AATTGATTGCTGGGTGATATTGGAAAATGTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TACCGTACAGACTGCCGGATATTATTTTTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CGACGTTCGACGAAATGCGCGATGGCGGTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCTGCGTCCCCGATGTCTGGCCCGACTGGTC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATGACCGGAACACTTCCGCCTGACGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP008697|2|1|3789324-3790147|CRT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GCCGGAAAATATTCATGATGGGGGTGGTTATGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GGGGCCGCCGTGTTCACATTTGCCTAATTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AACATGTCTTTCGTCAATTTTGGCGCTATAAA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATAAACGAGGTGAATTTATGGAAACTGTA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GTTAGTTTTCTGAAAAAAATTGTTTTCTTACGC
TGGTTTATCCCCGCTGGCGCGGGGAACTC	AATATTGTCGTGGACAAATGCCGGTGTTATTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCGAGACACTTCTCTGCAAAATTAATGAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CAGGTATCAAGAAATAATCGAAGCCTTCATGA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AATTGATTGCTGGGTGATATTGGAAAATGTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TACCGTACAGACTGCCGGATATTATTTTTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CGACGTTCGACGAAATGCGCGATGGCGGTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCTGCGTCCCCGATGTCTGGCCCGACTGGTC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATGACCGGAACACTTCCGCCTGACGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP008697|2|1|3789386-3790147|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GGGGCCGCCGTGTTCACATTTGCCTAATTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AACATGTCTTTCGTCAATTTTGGCGCTATAAA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATAAACGAGGTGAATTTATGGAAACTGTA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	GTTAGTTTTCTGAAAAAAATTGTTTTCTTACGC
TGGTTTATCCCCGCTGGCGCGGGGAACTC	AATATTGTCGTGGACAAATGCCGGTGTTATTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCGAGACACTTCTCTGCAAAATTAATGAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CAGGTATCAAGAAATAATCGAAGCCTTCATGA
CGGTTTATCCCCGCTGGCGCGGGGAACTC	AATTGATTGCTGGGTGATATTGGAAAATGTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TACCGTACAGACTGCCGGATATTATTTTTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	CGACGTTCGACGAAATGCGCGATGGCGGTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TTCTGCGTCCCCGATGTCTGGCCCGACTGGTC
CGGTTTATCCCCGCTGGCGCGGGGAACTC	TATATGACCGGAACACTTCCGCCTGACGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008697.1\|WP_022646031.1\|3781878_3782928_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP008697.1\|WP_001173673.1\|3785010_3785616_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP008697.1\|WP_001290706.1\|3800069_3801782_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP008697.1\|WP_000281399.1\|3791471_3792071_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP008697.1\|WP_022646037.1\|3792734_3793826_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP008697.1\|WP_022646040.1\|3799261_3799996_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP008697.1\|WP_022646033.1\|3788204_3789242_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP008697.1\|WP_000254708.1\|3780515_3781142_-\|protein-L-isoaspartate-O-methyltransferase	unknown	unknown	gnl\|CDD\|178974
NZ_CP008697.1\|WP_001246104.1\|3784637_3784961_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP008697.1\|WP_022646039.1\|3796236_3798903_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP008697.1\|WP_000246131.1\|3783403_3784114_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP008697.1\|WP_001219242.1\|3782924_3783404_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP008697.1\|WP_000752798.1\|3793838_3794321_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|187801
NZ_CP008697.1\|WP_000517476.1\|3784132_3784444_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP008697.1\|WP_022646034.1\|3790252_3790537_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP008697.1\|WP_022646032.1\|3785615_3787043_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP008697.1\|WP_000372392.1\|3787044_3787953_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP008697.1\|WP_022646035.1\|3790538_3791456_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP008697.1\|WP_023908987.1\|3792057_3792732_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
NZ_CP008697.1\|WP_022646038.1\|3794313_3795822_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|236613

Protein	Function_ID	Function_description	E-value
NZ_CP008697.1\|WP_022646031.1\|3781878_3782928_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP008697.1\|WP_001173673.1\|3785010_3785616_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP008697.1\|WP_001290706.1\|3800069_3801782_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP008697.1\|WP_000281399.1\|3791471_3792071_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	4.3792e-101
NZ_CP008697.1\|WP_022646037.1\|3792734_3793826_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	7.42279e-152
NZ_CP008697.1\|WP_022646040.1\|3799261_3799996_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	2.62447e-137
NZ_CP008697.1\|WP_022646033.1\|3788204_3789242_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP008697.1\|WP_000254708.1\|3780515_3781142_-\|protein-L-isoaspartate-O-methyltransferase	gnl\|CDD\|178974	PRK00312, pcm, protein-L-isoaspartate(D-aspartate) O-methyltransferase.	1.77123e-126
NZ_CP008697.1\|WP_001246104.1\|3784637_3784961_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP008697.1\|WP_022646039.1\|3796236_3798903_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	0
NZ_CP008697.1\|WP_000246131.1\|3783403_3784114_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.32778e-121
NZ_CP008697.1\|WP_001219242.1\|3782924_3783404_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP008697.1\|WP_000752798.1\|3793838_3794321_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187801	cd09670, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.51297e-33
NZ_CP008697.1\|WP_000517476.1\|3784132_3784444_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP008697.1\|WP_022646034.1\|3790252_3790537_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.20986e-62
NZ_CP008697.1\|WP_022646032.1\|3785615_3787043_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP008697.1\|WP_000372392.1\|3787044_3787953_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP008697.1\|WP_022646035.1\|3790538_3791456_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.75252e-159
NZ_CP008697.1\|WP_023908987.1\|3792057_3792732_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	1.34896e-101
NZ_CP008697.1\|WP_022646038.1\|3794313_3795822_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|236613	PRK09693, PRK09693, Cascade antiviral complex protein; Validated.	0

>NZ_CP008697.1|WP_022646033.1|3788204_3789242_+|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEVFDKAGIAVLSVEATNWNLGNKDGYQQRSKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIILPLVKKLAKAS
>NZ_CP008697.1|WP_000372392.1|3787044_3787953_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP008697.1|WP_022646032.1|3785615_3787043_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLILIDRLSNVTVGAGMVHEPVSQATAAPSQFSVFELELNALVRRHFPHWGARDLLGDK
>NZ_CP008697.1|WP_001173673.1|3785010_3785616_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP008697.1|WP_001246104.1|3784637_3784961_-|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP008697.1|WP_000517476.1|3784132_3784444_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP008697.1|WP_000246131.1|3783403_3784114_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKHVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP008697.1|WP_001219242.1|3782924_3783404_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP008697.1|WP_022646031.1|3781878_3782928_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHSREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELVELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP008697.1|WP_000254708.1|3780515_3781142_-|protein-L-isoaspartate-O-methyltransferase
MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
>NZ_CP008697.1|WP_022646034.1|3790252_3790537_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMLVVVTENVPPRLRGRLAIWLLEVRAGVYVGDVSARIREMIWEQISGLAEEGNVVMAWATNTESGFEFQTFGVNRRTPVDLDGLRLVSFLPV
>NZ_CP008697.1|WP_022646035.1|3790538_3791456_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYVLLAKQYGVKWNGRRYDPKDWEKGDTVNQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAGHRSS
>NZ_CP008697.1|WP_000281399.1|3791471_3792071_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSKVIIARAWSRDLYQLHQGLWHLFPNRPDAARDFLFHVEKRNTPEGCHVLLQSAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQKRLDSKGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFSGDGKSGKIQTVCFEGVITINDAPALIDLVQQGIGPAKSMGCGLLSLAPL
>NZ_CP008697.1|WP_023908987.1|3792057_3792732_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDEPILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCKASDPQKALLNYEPVGGDIYSEESVTGHYLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
>NZ_CP008697.1|WP_022646037.1|3792734_3793826_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSDYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKLVDEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMSELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWVRNNGEA
>NZ_CP008697.1|WP_000752798.1|3793838_3794321_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MADEIDAMALYRAWQQLDNGACAQIRRVSEPDELRDIPAFYRLVQPFGWENPRHQQALLRMVFCLSAGKNVIRHQDKKPEQTTGISLGRALANSGRINERRIFQLIRADRTADMVQLRRLLTHAEPVLDWPLMARMLTWWGKRERQQLLEDFVLTTNKNA
>NZ_CP008697.1|WP_022646038.1|3794313_3795822_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNLLIDNWIPVRPRNGGEVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPITTFVCGIDLRSTVLLNVLTIPRLQKQFPNELHTENQPTWVKPVKPNESVPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNENGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANINFSQADEVIADLRDKLHQLCEMLFNQSEAPYAHHPKLISTLALARATLYKHLRELKPQGGPSNG
>NZ_CP008697.1|WP_022646039.1|3796236_3798903_-|CRISPR-associated-helicase/endonuclease-Cas3
MEPFKYICHYWGKSSKSLTKGNDIHLLIYHCLDVAAVADCWWEQSVVLQNAFCQNEMLSKQMVKAWLLFFIALHDIGKFDIRFQYKSAESWLKLNPATPSLNGPSTQMCRKFNHGAAGLYWFNQDSLSEQSPGDFFSFFDAAPHPYESWFPWVEAVTGHHGFILHSQDQDKSRWEMPASLASYAAQDKQAREEWISVLEALFLTPAGLSINDIPPDCSSLLAGFCSLADWLGSWTTTNTFLFKEDAPSNINALRTYFQDRQQDASRVLELSGLVSNKRCYEGVHALLDNGYQPRQLQVLVDALPAAPGLTVIEAPTGSGKTETALAYAWKLIDQQLADSVIFALPTQATANAMLSRMEANASRLFTSPNLILAHGNSRFNHLFQSIKSRAFTEQGQEEAWVQCCQWLSQSNKKVFLGQIGVCTIDQVLISVLPVKHRFIRGLGIGRSVLIVDEVHAYDTYMNGLLEAVLKAQADVGGSVILLSATLPMKQKQKLLDTYGLHTDPEENNSAYPLINWRGVNGAQRFDLLAHSEQLPPRFSIRPEPIYLADMLPDLRMLERMIVAANAGAQVCLICNLVDVAQLCHQRLKELNNTQVDIDLFHARFTLNDRREKENRVISNFGKNGKRNVGRILVATQVVEQSLDVDFDWLITQHCPADLLFQRLGRLHRHHRKYRPAGFEVPLASVLLPDGEGYGRHEHIYSNVRVMWRTQQHIEELNGASLFFPDAYRQWLDSIYDDAEMDEPEWVIKGMDKYESAECEKRFKARKVLQWAEEYSLQDNDETILAVTRDGEMSLPLLPYLQTSSGKQLLDGQVYEDLSHEQQYEALALNRVNVPFTWKRNFSEVVDEDGVLWLEGKQNQDGWIWQGNNIVITYTRDEGMTRVIPANPK
>NZ_CP008697.1|WP_022646040.1|3799261_3799996_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWNNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP008697.1|WP_001290706.1|3800069_3801782_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD

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Crispr_ID: NZ_CP008697_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008697_3

3815693-3816944

Unclear

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
GGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

20 spacers

The CRISPR arrays of NZ_CP008697_3

>merge|NZ_CP008697|3|3815693-3816944|CRISPRCasFinder,CRT,PILER-CR
TGGTTCATCCCCGCTGGCGCGGGGAACACGTCCTGTTTTTGACCGGCGGTAAATGTTGCCTGCGGTTTATCCCCGCTGGCGCGGGGAACACAATATCCGTTCCTCGCTCTGCGTTTTCGTTGACGGTTTATCCCCGCTGGCGCGGGGAACACGGTCGGGTATTTCATTATGCATCCTGAACTAACGGTTTATCCCCGCTGGCGCGGGGAACACTATGCGCTTGCTGCTGCGTTGATGTACGCGGCCGGTTTATCCCCGCTGGCGCGGGGAACACTTAACTACCTGAACACCGGGAAGACTCCGGACCGGTTTATCCCCGCTGGCGCGGGGAACACGATTCAATGTCCGACGCATCCAAGTAAATATTCGGTTTATCCCCGCTGGCGCGGGGAACACGGATGAGCAGGGAGCAACAAAAGTAGCCGGAATGGTTTATCCCCGCTGGCGCGGGGAACACCCATACATTAACACGGTGTGGCCACATTTCAACGGTTTATCCCCGCTGGCGCGGGGAACACGCGCGGCCGCGATATCGTTAGCACTGGCTCCCGCGGTTTATCCCCGCTGGCGCGGGGAACACCAAAACACCTGAACGTTGAGATAGGGCTAAATCGGTTTATCCCCGCTGGCGCGGGGAACACGTTGTCGTATTCCTTAGAAATCTGATGCCAGCCCGGTTTATCCCCGCTGGCGCGGGGAACACTGACTGACCGGGAAAAGAAAACACCTGGCGAACGGTTTATCCCCGCTGGCGCGGGGAACACAATTTTTCCAGTGGTGTCGTTGTAATTAAGGACGGTTTATCCCCGCTGGCGCGGGGAACACAGGTTAAAGAGGCGCGCCGGGCGCTGGCTGGGCGGTTTATCCCCGCTGGCGCGGGGAACACATCCGTTAATTATTGAGAGAGCTATCAGCTATCGGTTTATCCCCGCTGGCGCGGGGAACACTCTAATTGCGCTTTGATAAATGGAGTTAAAGCCGGTTTATCCCCGCTGGCGCGGGGAACACGAATTCGGAATCACATTAAAAGGGAACCCGATAGGTTTATCCCCGCTGGCGCGGGGAACACCCAGGTCCCATTTGTCGATCGGCAGCGCCATTCGGTTTATCCCCGCTGGCGCGGGGAACACTGTTAATTCAGCAAGTTGAGATTGTGTCAGTCCGGTTTATCCCCGCTGGCGCGGGGAACACAAGAGAACAGCTTATATCTGATGCCGGTTTGCCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP008697|3|3|3815693-3816944|CRISPRCasFinder
TGGTTCATCCCCGCTGGCGCGGGGAACAC	GTCCTGTTTTTGACCGGCGGTAAATGTTGCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATATCCGTTCCTCGCTCTGCGTTTTCGTTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGTCGGGTATTTCATTATGCATCCTGAACTAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TATGCGCTTGCTGCTGCGTTGATGTACGCGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTAACTACCTGAACACCGGGAAGACTCCGGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GATTCAATGTCCGACGCATCCAAGTAAATATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGATGAGCAGGGAGCAACAAAAGTAGCCGGAA
TGGTTTATCCCCGCTGGCGCGGGGAACAC	CCATACATTAACACGGTGTGGCCACATTTCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCGGCCGCGATATCGTTAGCACTGGCTCCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAACACCTGAACGTTGAGATAGGGCTAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTGTCGTATTCCTTAGAAATCTGATGCCAGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGACTGACCGGGAAAAGAAAACACCTGGCGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATTTTTCCAGTGGTGTCGTTGTAATTAAGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGTTAAAGAGGCGCGCCGGGCGCTGGCTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCCGTTAATTATTGAGAGAGCTATCAGCTAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTAATTGCGCTTTGATAAATGGAGTTAAAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTCGGAATCACATTAAAAGGGAACCCGAT
AGGTTTATCCCCGCTGGCGCGGGGAACAC	CCAGGTCCCATTTGTCGATCGGCAGCGCCATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGTTAATTCAGCAAGTTGAGATTGTGTCAGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AAGAGAACAGCTTATATCTGATGCCGGTTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP008697|3|2|3815693-3816944|CRT
TGGTTCATCCCCGCTGGCGCGGGGAACAC	GTCCTGTTTTTGACCGGCGGTAAATGTTGCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATATCCGTTCCTCGCTCTGCGTTTTCGTTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGTCGGGTATTTCATTATGCATCCTGAACTAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TATGCGCTTGCTGCTGCGTTGATGTACGCGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTAACTACCTGAACACCGGGAAGACTCCGGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GATTCAATGTCCGACGCATCCAAGTAAATATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGATGAGCAGGGAGCAACAAAAGTAGCCGGAA
TGGTTTATCCCCGCTGGCGCGGGGAACAC	CCATACATTAACACGGTGTGGCCACATTTCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCGGCCGCGATATCGTTAGCACTGGCTCCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAACACCTGAACGTTGAGATAGGGCTAAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTGTCGTATTCCTTAGAAATCTGATGCCAGCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGACTGACCGGGAAAAGAAAACACCTGGCGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATTTTTCCAGTGGTGTCGTTGTAATTAAGGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGTTAAAGAGGCGCGCCGGGCGCTGGCTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCCGTTAATTATTGAGAGAGCTATCAGCTAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTAATTGCGCTTTGATAAATGGAGTTAAAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTCGGAATCACATTAAAAGGGAACCCGAT
AGGTTTATCCCCGCTGGCGCGGGGAACAC	CCAGGTCCCATTTGTCGATCGGCAGCGCCATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGTTAATTCAGCAAGTTGAGATTGTGTCAGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AAGAGAACAGCTTATATCTGATGCCGGTTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP008697|3|2|3815694-3816944|PILER-CR
GGTTCATCCCCGCTGGCGCGGGGAACAC	GTCCTGTTTTTGACCGGCGGTAAATGTTGCCTGC
GGTTTATCCCCGCTGGCGCGGGGAACAC	AATATCCGTTCCTCGCTCTGCGTTTTCGTTGAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GGTCGGGTATTTCATTATGCATCCTGAACTAAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TATGCGCTTGCTGCTGCGTTGATGTACGCGGCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TTAACTACCTGAACACCGGGAAGACTCCGGACC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GATTCAATGTCCGACGCATCCAAGTAAATATTC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GGATGAGCAGGGAGCAACAAAAGTAGCCGGAAT
GGTTTATCCCCGCTGGCGCGGGGAACAC	CCATACATTAACACGGTGTGGCCACATTTCAAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCGGCCGCGATATCGTTAGCACTGGCTCCCGC
GGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAACACCTGAACGTTGAGATAGGGCTAAATC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GTTGTCGTATTCCTTAGAAATCTGATGCCAGCCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TGACTGACCGGGAAAAGAAAACACCTGGCGAAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	AATTTTTCCAGTGGTGTCGTTGTAATTAAGGAC
GGTTTATCCCCGCTGGCGCGGGGAACAC	AGGTTAAAGAGGCGCGCCGGGCGCTGGCTGGGC
GGTTTATCCCCGCTGGCGCGGGGAACAC	ATCCGTTAATTATTGAGAGAGCTATCAGCTATC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TCTAATTGCGCTTTGATAAATGGAGTTAAAGCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	GAATTCGGAATCACATTAAAAGGGAACCCGATA
GGTTTATCCCCGCTGGCGCGGGGAACAC	CCAGGTCCCATTTGTCGATCGGCAGCGCCATTC
GGTTTATCCCCGCTGGCGCGGGGAACAC	TGTTAATTCAGCAAGTTGAGATTGTGTCAGTCC
GGTTTATCCCCGCTGGCGCGGGGAACAC	AAGAGAACAGCTTATATCTGATGCCGGTTTGCC
GGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008697.1\|WP_022646045.1\|3809645_3811100_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP008697.1\|WP_000046818.1\|3826236_3827538_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP008697.1\|WP_000147668.1\|3808214_3809624_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP008697.1\|WP_022646048.1\|3818248_3819121_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP008697.1\|WP_001071641.1\|3822430_3823222_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP008697.1\|WP_000109537.1\|3805601_3805862_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP008697.1\|WP_000254750.1\|3823293_3823629_-\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP008697.1\|WP_000186450.1\|3827594_3830351_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
NZ_CP008697.1\|WP_001199973.1\|3817283_3817955_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP008697.1\|WP_000210878.1\|3820565_3822203_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP008697.1\|WP_022646046.1\|3813576_3815055_+\|kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP008697.1\|WP_001164562.1\|3812272_3813550_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP008697.1\|WP_023908985.1\|3806600_3807461_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP008697.1\|WP_022646044.1\|3807457_3808237_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP008697.1\|WP_000021342.1\|3811169_3811955_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP008697.1\|WP_022646042.1\|3804339_3805611_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP008697.1\|WP_000581937.1\|3823628_3823877_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP008697.1\|WP_001130256.1\|3805878_3806454_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP008697.1\|WP_000036723.1\|3819180_3820479_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP008697.1\|WP_000226815.1\|3823954_3826189_-\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797

Protein	Function_ID	Function_description	E-value
NZ_CP008697.1\|WP_022646045.1\|3809645_3811100_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.79726e-81
NZ_CP008697.1\|WP_000046818.1\|3826236_3827538_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP008697.1\|WP_000147668.1\|3808214_3809624_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.9507e-51
NZ_CP008697.1\|WP_022646048.1\|3818248_3819121_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	2.57168e-95
NZ_CP008697.1\|WP_001071641.1\|3822430_3823222_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	6.52379e-160
NZ_CP008697.1\|WP_000109537.1\|3805601_3805862_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	3.07968e-40
NZ_CP008697.1\|WP_000254750.1\|3823293_3823629_-\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.22533e-74
NZ_CP008697.1\|WP_000186450.1\|3827594_3830351_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
NZ_CP008697.1\|WP_001199973.1\|3817283_3817955_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NZ_CP008697.1\|WP_000210878.1\|3820565_3822203_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP008697.1\|WP_022646046.1\|3813576_3815055_+\|kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	8.58462e-109
NZ_CP008697.1\|WP_001164562.1\|3812272_3813550_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.87501e-29
NZ_CP008697.1\|WP_023908985.1\|3806600_3807461_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	2.43837e-88
NZ_CP008697.1\|WP_022646044.1\|3807457_3808237_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	4.70543e-60
NZ_CP008697.1\|WP_000021342.1\|3811169_3811955_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	8.62537e-140
NZ_CP008697.1\|WP_022646042.1\|3804339_3805611_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	3.94463e-124
NZ_CP008697.1\|WP_000581937.1\|3823628_3823877_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP008697.1\|WP_001130256.1\|3805878_3806454_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	1.33799e-87
NZ_CP008697.1\|WP_000036723.1\|3819180_3820479_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP008697.1\|WP_000226815.1\|3823954_3826189_-\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0

>NZ_CP008697.1|WP_022646046.1|3813576_3815055_+|kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKTWAWSEDAAVMEKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFMPVESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNEDSIQSWSNA
>NZ_CP008697.1|WP_001164562.1|3812272_3813550_+|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSIIGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIIFTFLLFQKIRTADSAPAMASSK
>NZ_CP008697.1|WP_000021342.1|3811169_3811955_-|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP008697.1|WP_022646045.1|3809645_3811100_-|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDVEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNHLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWTLLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP008697.1|WP_000147668.1|3808214_3809624_-|MFS-transporter
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP008697.1|WP_022646044.1|3807457_3808237_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGNIGPDVSLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEDAVLLETVADLRFAPEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFITLEQRTENGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAAIIRKTVAVELPAMQCLHLARAEQRRGATLIDGQTVAEKAQKLWQNYLRQRMQP
>NZ_CP008697.1|WP_023908985.1|3806600_3807461_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTDKRPLCLSLARQAGADKNATLPSGMQQLNIVPGALPDWLVSLENLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVCNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEAMVTNIHADCQ
>NZ_CP008697.1|WP_001130256.1|3805878_3806454_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISHIVKKIKSAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP008697.1|WP_000109537.1|3805601_3805862_+|ferredoxin-family-protein
MSVARNLWRVADAPHIVPADSVERQTVQWLINACPAGLFSLTPEGDLRIDYRSCLECGTCRLLCDEKTLQQWRYPPSGFGITYRFG
>NZ_CP008697.1|WP_022646042.1|3804339_3805611_+|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTQALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRACYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLLGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL
>NZ_CP008697.1|WP_001199973.1|3817283_3817955_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP008697.1|WP_022646048.1|3818248_3819121_+|YgcG-family-protein
MRYFILIFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTRKLESIFNNTQVQIAVLIIPTTKDETIEQYATRVFNNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAKGLELAIIALNNQLTSQHQYSANPSESESASSSDYYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSSVCISAIYLLDLFLFSDKTFSIAVFFFFFTFTTIMVFTCLCVLQKKASGRSYHSDNSGSGGGSSGGGFSGGGGSSGGGGASGRW
>NZ_CP008697.1|WP_000036723.1|3819180_3820479_-|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP008697.1|WP_000210878.1|3820565_3822203_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP008697.1|WP_001071641.1|3822430_3823222_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEAQQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP008697.1|WP_000254750.1|3823293_3823629_-|endoribonuclease-MazF
MVSRYVPDTGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP008697.1|WP_000581937.1|3823628_3823877_-|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP008697.1|WP_000226815.1|3823954_3826189_-|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP008697.1|WP_000046818.1|3826236_3827538_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLECFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLHNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP008697.1|WP_000186450.1|3827594_3830351_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG

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Crispr_ID: NZ_CP008697_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP008697_4

4959142-4959247

Orphan

Consensus_repeat	Method
GGGGCAACCGTTGCGCCGTTGCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP008697_4

>merge|NZ_CP008697|4|4959142-4959247|CRISPRCasFinder
GGGGCAACCGTTGCGCCGTTGCCTNNCCGTCTGGCTGGTGACAGGGATCTCCGCCGTGCCGTCCGGCTCTGTAATCACCGTTGGGGCAACCGTTGCACCGTTGCCT

>NZ_CP008697|4|4|4959142-4959247|CRISPRCasFinder
GGGGCAACCGTTGCGCCGTTGCCT	NNCCGTCTGGCTGGTGACAGGGATCTCCGCCGTGCCGTCCGGCTCTGTAATCACCGTT
GGGGCAACCGTTGCACCGTTGCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP008697.1\|WP_022646290.1\|4953470_4955168_+\|HilA-family-transcriptional-regulator-EilA	unknown	unknown	gnl\|CDD\|237080
NZ_CP008697.1\|WP_060684517.1\|4966692_4967145_-\|DUF1198-domain-containing-protein	unknown	unknown	gnl\|CDD\|369048
NZ_CP008697.1\|WP_022646286.1\|4945634_4946558_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP008697.1\|WP_000779398.1\|4946561_4947380_-\|lipoprotein-NlpA	unknown	unknown	gnl\|CDD\|182119
NZ_CP008697.1\|WP_023908928.1\|4951918_4953268_+\|IpaD/SipD/SspD-family-type-III-secretion-system-needle-tip-protein	unknown	unknown	gnl\|CDD\|274198
NZ_CP008697.1\|WP_001306625.1\|4947588_4947882_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008697.1\|WP_000879194.1\|4970519_4971911_-\|hexose-6-phosphate:phosphate-antiporter	unknown	unknown	gnl\|CDD\|236564
NZ_CP008697.1\|WP_000125643.1\|4966253_4966577_+\|DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225495
NZ_CP008697.1\|WP_022646288.1\|4948929_4950711_+\|YopB/SseC-family-type-III-secretion-system-translocon-subunit	unknown	unknown	gnl\|CDD\|185272
NZ_CP008697.1\|WP_001525914.1\|4967197_4968532_-\|adenine-permease-AdeQ	unknown	unknown	gnl\|CDD\|225161
NZ_CP008697.1\|WP_001172866.1\|4944339_4945524_+\|sugar-efflux-transporter	unknown	unknown	gnl\|CDD\|184973
NZ_CP008697.1\|WP_001288548.1\|4964499_4965684_-\|purine-ribonucleoside-efflux-pump-NepI	unknown	unknown	gnl\|CDD\|182309
NZ_CP008697.1\|WP_001301991.1\|4972048_4973368_-\|MFS-transporter-family-glucose-6-phosphate-receptor-UhpC	unknown	unknown	gnl\|CDD\|183266
NZ_CP008697.1\|WP_022646287.1\|4948183_4948681_+\|SycD/LcrH-family-type-III-secretion-system-chaperone	unknown	unknown	gnl\|CDD\|185231
NZ_CP008697.1\|WP_022646294.1\|4973377_4974880_-\|signal-transduction-histidine-protein-kinase/phosphatase-UhpB	unknown	unknown	gnl\|CDD\|236945
NZ_CP008697.1\|WP_000257047.1\|4950723_4951875_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008697.1\|WP_022646293.1\|4968706_4970473_+\|adenine-deaminase	unknown	unknown	gnl\|CDD\|182201
NZ_CP008697.1\|WP_000633668.1\|4974879_4975470_-\|transcriptional-regulator-UhpA	unknown	unknown	gnl\|CDD\|182408
NZ_CP008697.1\|WP_059337323.1\|4977348_4977831_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP008697.1\|WP_001328030.1\|4943809_4943956_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226452

Protein	Function_ID	Function_description	E-value
NZ_CP008697.1\|WP_022646288.1\|4948929_4950711_+\|YopB/SseC-family-type-III-secretion-system-translocon-subunit	gnl\|CDD\|185272	PRK15374, PRK15374, type III secretion system needle tip complex protein SipB.	3.72569e-27
NZ_CP008697.1\|WP_060684517.1\|4966692_4967145_-\|DUF1198-domain-containing-protein	gnl\|CDD\|369048	pfam06711, DUF1198, Protein of unknown function (DUF1198). This family consists of several bacterial proteins of around 150 residues in length which are specific to Escherichia coli, Salmonella species and Yersinia pestis. The function of this family is unknown.	7.98107e-80
NZ_CP008697.1\|WP_022646286.1\|4945634_4946558_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.21125e-64
NZ_CP008697.1\|WP_000779398.1\|4946561_4947380_-\|lipoprotein-NlpA	gnl\|CDD\|182119	PRK09861, PRK09861, lipoprotein NlpA.	0
NZ_CP008697.1\|WP_023908928.1\|4951918_4953268_+\|IpaD/SipD/SspD-family-type-III-secretion-system-needle-tip-protein	gnl\|CDD\|274198	TIGR02553, pathogenicity_island_1_effector_protein, type III effector protein IpaD/SipD/SspD. These proteins are found within type III secretion operons and have been shown to be secreted by that system.	3.24881e-33
NZ_CP008697.1\|WP_001301991.1\|4972048_4973368_-\|MFS-transporter-family-glucose-6-phosphate-receptor-UhpC	gnl\|CDD\|183266	PRK11663, PRK11663, glucose-6-phosphate receptor/MFS transporter UhpC.	0
NZ_CP008697.1\|WP_000879194.1\|4970519_4971911_-\|hexose-6-phosphate:phosphate-antiporter	gnl\|CDD\|236564	PRK09556, uhpT, hexose-6-phosphate:phosphate antiporter.	0
NZ_CP008697.1\|WP_000125643.1\|4966253_4966577_+\|DNA-binding-transcriptional-regulator	gnl\|CDD\|225495	COG2944, COG2944, Predicted transcriptional regulator [Transcription].	2.36291e-47
NZ_CP008697.1\|WP_001525914.1\|4967197_4968532_-\|adenine-permease-AdeQ	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.21458e-177
NZ_CP008697.1\|WP_001172866.1\|4944339_4945524_+\|sugar-efflux-transporter	gnl\|CDD\|184973	PRK15011, PRK15011, sugar efflux transporter SetB.	0
NZ_CP008697.1\|WP_001288548.1\|4964499_4965684_-\|purine-ribonucleoside-efflux-pump-NepI	gnl\|CDD\|182309	PRK10213, nepI, purine ribonucleoside efflux pump NepI.	0
NZ_CP008697.1\|WP_022646287.1\|4948183_4948681_+\|SycD/LcrH-family-type-III-secretion-system-chaperone	gnl\|CDD\|185231	PRK15331, PRK15331, type III secretion system translocator chaperone SicA.	5.89585e-41
NZ_CP008697.1\|WP_022646294.1\|4973377_4974880_-\|signal-transduction-histidine-protein-kinase/phosphatase-UhpB	gnl\|CDD\|236945	PRK11644, PRK11644, signal transduction histidine-protein kinase/phosphatase UhpB.	0
NZ_CP008697.1\|WP_022646290.1\|4953470_4955168_+\|HilA-family-transcriptional-regulator-EilA	gnl\|CDD\|237080	PRK12370, PRK12370, HilA/EilA family virulence transcriptional regulator.	0
NZ_CP008697.1\|WP_022646293.1\|4968706_4970473_+\|adenine-deaminase	gnl\|CDD\|182201	PRK10027, PRK10027, cryptic adenine deaminase; Provisional.	0
NZ_CP008697.1\|WP_000633668.1\|4974879_4975470_-\|transcriptional-regulator-UhpA	gnl\|CDD\|182408	PRK10360, PRK10360, transcriptional regulator UhpA.	1.56392e-139
NZ_CP008697.1\|WP_001328030.1\|4943809_4943956_+\|hypothetical-protein	gnl\|CDD\|226452	COG3943, COG3943, Virulence protein [General function prediction only].	1.75939e-13

>NZ_CP008697.1|WP_022646290.1|4953470_4955168_+|HilA-family-transcriptional-regulator-EilA
MQLQHGKNNTQQYIFGDFVLKNNGILLFKNKEYHIPPKELGVIILLLNADGEIVSKEEIIDKVWSASVASDESLTRCIYALRKLLHENKQCKYIETVYGRGYRFTVPIVIVTDNEPVKSTTTLAVFPFRTEGSINVLKLHYELVQGLSKYAFCGLDILPASVTNEASDFSTIHQFINKTGPEYYIMGQVVHYGKNWRLFIELIHARTHKLIDHQSIDFNPDNPLSVLLSQVINILIEKIPNINFKSINTQQMPSLDSAVMYMNGRMEMYRYTPESLKRALVIFRDCVSTQPQNTLPYCCLAECHISLALLGISEQKQAITTAVTSIEKALEINPSNSQALGLLGLISGLKDEHSVSNVLFKQAHLLKPNSPDVYYYQSLLCFLNGDLARAFNLIEKSIALEPNKMGISILKLIILYYTSPLDNAISFALNLNSQNTCNNPIITSILAMFMALKGHNDKAKSLLLKLEPEHGLDYTCVNSLYTKFLIYGASIKNDIMKLLANINTNKINGVILPLIYTVYGKKEYEKRWQQLIKENDLWSNVLLHDPRLLSVKNEFNTIGVMRTSA
>NZ_CP008697.1|WP_023908928.1|4951918_4953268_+|IpaD/SipD/SspD-family-type-III-secretion-system-needle-tip-protein
MINKDNNLNIDILRQQNANIPLQEASSQSEEPHQLENSKSEGNLHNSASKDNNIGAMLKKDVEKLSTLVSERSPRNEDWKCQHDIQLNFVKNMLRNFPTENLSEKGSALLHESYSLIKNVLQLTENVNTIDGKLKDPAKILTLHNSVRKTLANVAHNTTGSSAMASTKGTLNHAIASLESSAPEMRSSATSSTLTASSSNEFKSDKYICSDIADLMSVLGSDYLEIYANSVEIMSAYWQDFSEHIQSNMGKWTHSNKKGDAIVFDVNAFQKALMHFYYIDKYPNGDFHYHYNPDYVLYPPAPADKIGVPLEEAEKWCAALGLPVIPPDPKHRTPSPIVEVEPQGSGLYVIIPNPQIIDSMSQSSDSMVHRDDKGKEKNISKEFTGYEISTAEYQAWLAGYNGQAENMKTDVQVITTKYSTANSTYDTIIKLLSSTITALFDSAKDYLRF
>NZ_CP008697.1|WP_000257047.1|4950723_4951875_+|hypothetical-protein
MATYEIKNATSIHNINNLDKTIFDRDYGKENNIPNDNKIVQYYNLKDIKHDISSQFIILKNTDREVCPELRVKLLDNLNYSRNTLDNLRGDLDQATISFSQSSSSAEQSSIKISKYNILDMLDNLTMRQQAVMEEFLRVFTSMYKASAMSEAIMSNVFEQLVQYQKTETVHATMASSAGVLAGSTVGAAGAAASVVANFRSHPEKMQTLTPDQKHTISGTDDKTQRGLKREVQDQQAYLKQIDEEIKTTTKDTTLDEEQKEETLKYYDKEKETTEEKIRDKNERISIKHNRKYNKYFTIGKADVLSQLVNQSTQASLRILESTTHAEKDIVEQAKNVMHSVMSSYLDQINRDVQGRDQALNLLQQIIQTIIDTDSAIVQGIRS
>NZ_CP008697.1|WP_022646288.1|4948929_4950711_+|YopB/SseC-family-type-III-secretion-system-translocon-subunit
MSAPITGQTITFEQISETLRTQYSDAEKRLQDSSKTQVDPMRLNKNPKSLDNDIRARLENKPMLAPPEIQVSDSDNATTAKTNDARLTMILGNLTGIADQDITKRLHNNLDSTLLRHEMAHNKFRELSDAYSSSLDDAQKADDIMHQANNNYNAVDKKVQSLEKKVNTLNQELSQLQPGDPQYNKVLTQKNAAEKTLTLSLQKKSLAEKSLNTAIMDADAAIGQSMEIFDEIQQQEQINNFTTNICLTQENQKNRNATATFILLITSVMEVIGDTNCDSIKNQSEVMKEINHVRENKLNETARKYTTTTKVLKIVNECVTVVTFAVSAVLIVVGLLAAVPSGGSSIAGALALIGGIAGAVVLGVDITCQIALGTTATGWILGKVVEGLSAAIKTVDPTLLAITALLDVIGVDQDTIELVKSIYASAAASIVMATVMIGAAVICSVAIGAVVSALSKTAAEEVTKEITSTIKSTIESIINSVSKNIIKVLDSVCSVLQTSAVVLKLIAKISNGLEKIGLLICAIATSTMNCFVAGNSADMAILQQDMSNLSKTREQMLSVLQRVDKTVEQEVSQMVRVLQHRTEALKFASHSIV
>NZ_CP008697.1|WP_022646287.1|4948183_4948681_+|SycD/LcrH-family-type-III-secretion-system-chaperone
MESANLDLEENKEIASKFERALGMGATLAELHGITPDTLEGVYAYAYNFYEKGRLDEAELFFKFLCIYDFQNYNYLKGYAAVCQLKKDYQKAFDMYHICLMLSPDNDFSLVYYMGQCQMGLKNIKMATELFNTVVTYSQNEKIKEMATAYLELLTANTEEEVRTE
>NZ_CP008697.1|WP_001306625.1|4947588_4947882_+|hypothetical-protein
MKPTMLLMITVFLTFPAISQAESPFSSLQSAKEKTTVLQDLRKICTPQASLSDEAWEKLMLSDESNKQHIREAIVAMERNNQNNYWEALGKVECPDM
>NZ_CP008697.1|WP_000779398.1|4946561_4947380_-|lipoprotein-NlpA
MKLTTHHLRAGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQDVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGYKLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLIILKEGKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVHDSVFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSSEVAKAAETIFNGGAVPGW
>NZ_CP008697.1|WP_022646286.1|4945634_4946558_+|DMT-family-transporter
MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRLIFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATATVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLVGTFLLVTHGNPTSLSISPAALFWGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLILAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDWLGTLLILSSVILISVDSRRRARKINRPARDE
>NZ_CP008697.1|WP_001172866.1|4944339_4945524_+|sugar-efflux-transporter
MQKTATTPSKILDLTAAAFLLVAFLTGIAGALQTPTLSIFLADELKARPIMVGFFFTGSAIMGILVSQFLARHSDKQGDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFASTANPQMFALAREHADRTGRETVMFSTFLRAQISLAWVIGPPLAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLPSIQRNIPVVTQPVEILPSIHRKRDTRLLFVVCSMMWAANNLYMINMPLFIIDELHLTDKLAGEMIGIAAGLEIPMMLIAGYYMKRIGKRLLMLIAIVSGMCFYASVLMATTPAIELELQILNAIFLGILCGIGMLYFQDLMPEKIGSATTLYANTSRVGWIIAGSVDGIMVEIWSYHALFWLAIGMLGIAMICLLFIKDI
>NZ_CP008697.1|WP_001328030.1|4943809_4943956_+|hypothetical-protein
MDDERLKNPPVGSSVLERIRDIRASMRRVYLQVICPPADSQPTVSPLR
>NZ_CP008697.1|WP_001288548.1|4964499_4965684_-|purine-ribonucleoside-efflux-pump-NepI
MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLTPMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFILKRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVKMK
>NZ_CP008697.1|WP_000125643.1|4966253_4966577_+|DNA-binding-transcriptional-regulator
MTAKTKFKSPAFEAIHSAAAGLSSVDAISAETMRTFDKACLTSVQDLQPVEIKALREKLKVSQPVFAHYLNTSVSTVQKWESGAKRPNGISLKLLSIVQKHGLEVLL
>NZ_CP008697.1|WP_060684517.1|4966692_4967145_-|DUF1198-domain-containing-protein
MIWIMLATLAVVFVIGFRVLTSGARKAIRRLSDRLNIDVVPVGSMVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNMLQWHRILQKARLAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH
>NZ_CP008697.1|WP_001525914.1|4967197_4968532_-|adenine-permease-AdeQ
MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMVYIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGIFANLPVALAPAMGLNAFFAFVVVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALMGLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCCGLFFGDVHFSGVYSIPPDISGVIGEVDLSGALSLELAGIIFSFMLINLFDSSGTLIGVTDKAGLIDSNGKFPNMNKALYVDSVSSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTAVVVGVMFLLVMFFSPLVAMVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITTVMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD
>NZ_CP008697.1|WP_022646293.1|4968706_4970473_+|adenine-deaminase
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAKESARLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEFTE
>NZ_CP008697.1|WP_000879194.1|4970519_4971911_-|hexose-6-phosphate:phosphate-antiporter
MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYLIRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTFLGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPESYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRIGIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIALALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKGTFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERKIRREKKIQQLTVA
>NZ_CP008697.1|WP_001301991.1|4972048_4973368_-|MFS-transporter-family-glucose-6-phosphate-receptor-UhpC
MLPFLKAPADAPLMTDKHEIDARYRYWRRHILLTIWLGYALFYFTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWNTAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLGASLAGWPLAKVLDTWHWSGFFVVIAIAAGISALLLLPFLNAQTPREA
>NZ_CP008697.1|WP_022646294.1|4973377_4974880_-|signal-transduction-histidine-protein-kinase/phosphatase-UhpB
MKTFFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFPFGLRLGLMLQCPRGYWPVLLGAEWLLIYWLMQAVGLTHFSLLMIGSLLTLLPVALISRYRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWHYLANNIWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALPIIALAWHYGWQGALIATLMNAIALIASQTWRDHSVDLLLSLLVQSLTGLLLGAGIQRLRELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLAADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQQGFGLTGMRERVTALGGTLTISCLHGTRVSVSLPQRYV
>NZ_CP008697.1|WP_000633668.1|4974879_4975470_-|transcriptional-regulator-UhpA
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW
>NZ_CP008697.1|WP_059337323.1|4977348_4977831_-|hypothetical-protein
MVELVYFNDNDCARVRELLKKSNGNIADDKIDEIIACLSSHQGITCFYYSSVQGYQSYLKNTSQDVSELLSKSLDDAISSTSGLKNSGNTFFGTGKYLKEMDFTINGFSQKMYLMAVNNVGNEVKLQCSRYFTTGRVDKENSKIDKVAFTFFGAATTADL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP008697_3	3.7\|3816089\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816089-3816120	32	NZ_CP008697.1	3836746-3836777	1	0.969
NZ_CP008697_3	3.27\|3816089\|33\|NZ_CP008697\|PILER-CR	3816089-3816121	33	NZ_CP008697.1	3836745-3836777	1	0.97

1. spacer 3.7|3816089|32|NZ_CP008697|CRISPRCasFinder,CRT matches to position: 3836746-3836777, mismatch: 1, identity: 0.969

ggatgagcagggagcaacaaaagtagccggaa	CRISPR spacer
ggatgagcagggagcaacaaaagtagctggaa	Protospacer
***************************.****

2. spacer 3.27|3816089|33|NZ_CP008697|PILER-CR matches to position: 3836745-3836777, mismatch: 1, identity: 0.97

ggatgagcagggagcaacaaaagtagccggaat	CRISPR spacer
ggatgagcagggagcaacaaaagtagctggaat	Protospacer
***************************.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP008697_2	2.4\|3789537\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789537-3789568	32	MF547662	Clostridioides phage LIBA6276, complete genome	37369-37400	4	0.875
NZ_CP008697_2	2.4\|3789537\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789537-3789568	32	MF547663	Clostridioides phage LIBA2945, complete genome	37369-37400	4	0.875
NZ_CP008697_2	2.4\|3789537\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789537-3789568	32	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	83504-83535	5	0.844
NZ_CP008697_2	2.12\|3790026\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3790026-3790057	32	MK972713	Salmonella phage SW5, complete genome	27687-27718	5	0.844
NZ_CP008697_2	2.12\|3790026\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3790026-3790057	32	MK972714	Salmonella phage SW3, complete genome	27909-27940	5	0.844
NZ_CP008697_2	2.12\|3790026\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3790026-3790057	32	NC_049460	Salmonella phage SI7, complete genome	18129-18160	5	0.844
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1203814-1203845	6	0.812
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1167510-1167541	6	0.812
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1175642-1175673	7	0.781
NZ_CP008697_2	2.13\|3790087\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3790087-3790118	32	LR597649	Escherichia phage ESSI2_ev015 genome assembly, chromosome: 1	17850-17881	7	0.781
NZ_CP008697_2	2.13\|3790087\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3790087-3790118	32	NC_049393	Escherichia phage ESSI2_ev040 genome assembly, chromosome: 1	17628-17659	7	0.781
NZ_CP008697_2	2.13\|3790087\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3790087-3790118	32	NC_049394	Escherichia phage ESSI2_ev129 genome assembly, chromosome: 1	17890-17921	7	0.781
NZ_CP008697_3	3.18\|3816762\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816762-3816793	32	NC_018022	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence	373536-373567	7	0.781
NZ_CP008697_2	2.6\|3789660\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789660-3789691	32	NZ_CP008818	Ochrobactrum anthropi strain OAB plasmid 2, complete sequence	52227-52258	8	0.75
NZ_CP008697_2	2.6\|3789660\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789660-3789691	32	NC_009671	Ochrobactrum anthropi ATCC 49188 plasmid pOANT03, complete sequence	23638-23669	8	0.75
NZ_CP008697_2	2.8\|3789782\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789782-3789813	32	MN694482	Marine virus AFVG_250M11, complete genome	1728-1759	8	0.75
NZ_CP008697_2	2.9\|3789843\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789843-3789874	32	NZ_CP024236	Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed4, complete sequence	57083-57114	8	0.75
NZ_CP008697_2	2.10\|3789904\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789904-3789935	32	CP022610	Escherichia coli strain ATCC 700415 plasmid unnamed, complete sequence	10541-10572	8	0.75
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NC_031109	Gordonia phage Jumbo, complete genome	25391-25422	8	0.75
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NZ_CP050093	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence	398774-398805	8	0.75
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NC_008384	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence	565533-565564	8	0.75
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NZ_CP042332	Bosea sp. F3-2 plasmid pB32-1, complete sequence	63515-63546	8	0.75
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	350647-350678	8	0.75
NZ_CP008697_3	3.4\|3815906\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3815906-3815937	32	MN855615	Siphoviridae sp. isolate 320, complete genome	7076-7107	8	0.75
NZ_CP008697_3	3.4\|3815906\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3815906-3815937	32	NC_034248	Rhizobium phage RHEph10, complete genome	31444-31475	8	0.75
NZ_CP008697_3	3.9\|3816211\|33\|NZ_CP008697\|CRISPRCasFinder,CRT	3816211-3816243	33	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	413541-413573	8	0.758
NZ_CP008697_3	3.13\|3816457\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816457-3816488	32	NC_013085	Synechococcus phage S-RSM4, complete genome	75536-75567	8	0.75
NZ_CP008697_3	3.13\|3816457\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816457-3816488	32	FM207411	Synechococcus phage S-RSM4 complete genome	75536-75567	8	0.75
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	NZ_CP053709	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence	405764-405795	8	0.75
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	NZ_CP053710	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence	354033-354064	8	0.75
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	NZ_CP053712	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed5, complete sequence	91487-91518	8	0.75
NZ_CP008697_1	1.2\|1755095\|32\|NZ_CP008697\|CRISPRCasFinder	1755095-1755126	32	NZ_CP045060	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence	9736-9767	9	0.719
NZ_CP008697_1	1.2\|1755095\|32\|NZ_CP008697\|CRISPRCasFinder	1755095-1755126	32	NZ_CP045053	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence	9737-9768	9	0.719
NZ_CP008697_1	1.2\|1755095\|32\|NZ_CP008697\|CRISPRCasFinder	1755095-1755126	32	NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	9736-9767	9	0.719
NZ_CP008697_2	2.4\|3789537\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789537-3789568	32	MN693584	Marine virus AFVG_25M163, complete genome	29591-29622	9	0.719
NZ_CP008697_2	2.4\|3789537\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789537-3789568	32	MN103543	Pseudomonas phage vB_PaeM_PS119XW, complete genome	258501-258532	9	0.719
NZ_CP008697_2	2.4\|3789537\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789537-3789568	32	MK599315	Pseudomonas phage PA1C, complete genome	257887-257918	9	0.719
NZ_CP008697_2	2.7\|3789721\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789721-3789752	32	MT446414	UNVERIFIED: Escherichia virus TH43, complete genome	38100-38131	9	0.719
NZ_CP008697_2	2.9\|3789843\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789843-3789874	32	NZ_CP053709	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence	137043-137074	9	0.719
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NZ_CP017077	Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence	555186-555217	9	0.719
NZ_CP008697_2	2.11\|3789965\|32\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789965-3789996	32	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	471692-471723	9	0.719
NZ_CP008697_3	3.2\|3815784\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3815784-3815815	32	MK448690	Streptococcus phage Javan169, complete genome	9831-9862	9	0.719
NZ_CP008697_3	3.2\|3815784\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3815784-3815815	32	MK448854	Streptococcus phage Javan146, complete genome	11811-11842	9	0.719
NZ_CP008697_3	3.6\|3816028\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816028-3816059	32	NZ_CP016721	Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11B, complete sequence	30466-30497	9	0.719
NZ_CP008697_3	3.6\|3816028\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816028-3816059	32	NZ_CP016727	Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08B, complete sequence	30464-30495	9	0.719
NZ_CP008697_3	3.12\|3816396\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816396-3816427	32	MW084976	Bacillus phage Kirov, complete genome	56770-56801	9	0.719
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	JX469828	Uncultured bacterium plasmid pRSB223, complete sequence	47585-47616	9	0.719
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	JX469829	Uncultured bacterium plasmid pB1, complete sequence	23183-23214	9	0.719
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	393203-393234	9	0.719
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	NC_008766	Acidovorax sp. JS42 plasmid pAOVO02, complete sequence	3158-3189	9	0.719
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	569059-569090	9	0.719
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	NZ_MN366361	Bacterium plasmid pALTS33, complete sequence	54575-54606	9	0.719
NZ_CP008697_3	3.24\|3815906\|33\|NZ_CP008697\|PILER-CR	3815906-3815938	33	MN855615	Siphoviridae sp. isolate 320, complete genome	7075-7107	9	0.727
NZ_CP008697_3	3.29\|3816211\|34\|NZ_CP008697\|PILER-CR	3816211-3816244	34	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	413540-413573	9	0.735
NZ_CP008697_2	2.5\|3789598\|33\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789598-3789630	33	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	13087-13119	10	0.697
NZ_CP008697_3	3.14\|3816518\|32\|NZ_CP008697\|CRISPRCasFinder,CRT	3816518-3816549	32	NC_004929	Ruegeria sp. PR1b plasmid pSD20, complete sequence	67373-67404	10	0.688
NZ_CP008697_2	2.5\|3789598\|33\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789598-3789630	33	NC_011260	Borrelia recurrentis A1 plasmid pl53, complete sequence	3621-3653	11	0.667
NZ_CP008697_2	2.5\|3789598\|33\|NZ_CP008697\|CRISPRCasFinder,CRT,PILER-CR	3789598-3789630	33	NC_011260	Borrelia recurrentis A1 plasmid pl53, complete sequence	6849-6881	11	0.667

1. spacer 2.4|3789537|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 4, identity: 0.875

-tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
ttttataag-gaggtgaatttatggaaacagta	Protospacer
 * *****. ******************* ***

2. spacer 2.4|3789537|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 4, identity: 0.875

-tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
ttttataag-gaggtgaatttatggaaacagta	Protospacer
 * *****. ******************* ***

3. spacer 2.4|3789537|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

-tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
ttttatagg-gaggtgaatttatggaaacagta	Protospacer
 * ****.. ******************* ***

4. spacer 2.12|3790026|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MK972713 (Salmonella phage SW5, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

5. spacer 2.12|3790026|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MK972714 (Salmonella phage SW3, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

6. spacer 2.12|3790026|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NC_049460 (Salmonella phage SI7, complete genome) position: , mismatch: 5, identity: 0.844

ttctgcgtccccgatgtctggcccgactggtc	CRISPR spacer
ttggccgtgctcgatgtctggcccgactggtc	Protospacer
**   *** *.*********************

7. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 6, identity: 0.812

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cggcgttcgacgaactgcgcgatggccgcgtg	Protospacer
**.*********** *********** *.  *

8. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 6, identity: 0.812

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
caacgatggacgaaatgcgcgatggcgaacgc	Protospacer
*.*** * *******************. **

9. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 7, identity: 0.781

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cagcgatggacgaaatgcgcgatggcgaacgc	Protospacer
*..** * *******************. **

10. spacer 2.13|3790087|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to LR597649 (Escherichia phage ESSI2_ev015 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

11. spacer 2.13|3790087|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NC_049393 (Escherichia phage ESSI2_ev040 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

12. spacer 2.13|3790087|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NC_049394 (Escherichia phage ESSI2_ev129 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.781

tatatgaccggaacacttccgcctgacgtttg	CRISPR spacer
tgtaagaccggaacacttcagcctgagccttt	Protospacer
*.** ************** ******  .**

13. spacer 3.18|3816762|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NC_018022 (Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence) position: , mismatch: 7, identity: 0.781

-ccaggtcccatttgtcgatcggcagcgccatt	CRISPR spacer
agcatgt-gcatttgtccatcggcatcgccatc	Protospacer
  ** **  ******** ******* ******.

14. spacer 2.6|3789660|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP008818 (Ochrobactrum anthropi strain OAB plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.75

aatattgtcgtggacaaatgccggtgttattg-	CRISPR spacer
aattgtgtcgtggacaaatgcc-gcgtcgccga	Protospacer
***  ***************** *.**....*

15. spacer 2.6|3789660|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NC_009671 (Ochrobactrum anthropi ATCC 49188 plasmid pOANT03, complete sequence) position: , mismatch: 8, identity: 0.75

aatattgtcgtggacaaatgccggtgttattg-	CRISPR spacer
aattgtgtcgtggacaaatgcc-gcgtcgccga	Protospacer
***  ***************** *.**....*

16. spacer 2.8|3789782|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MN694482 (Marine virus AFVG_250M11, complete genome) position: , mismatch: 8, identity: 0.75

caggtatcaagaaataatcgaagccttcatga	CRISPR spacer
aactaaactagaaaaaatcgaagccttaatga	Protospacer
 *   * * ***** ************ ****

17. spacer 2.9|3789843|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024236 (Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

aattgattgctgggtgatattggaaaatgttg-	CRISPR spacer
cccggagtgctgggtgatattagaaaa-gttac	Protospacer
  . ** **************.***** ***.

18. spacer 2.10|3789904|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to CP022610 (Escherichia coli strain ATCC 700415 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

taccgtacagactgccggatattatttttttg	CRISPR spacer
ctcgctaaagactgccggatatgatttttctt	Protospacer
. *  ** ************** ******.*

19. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NC_031109 (Gordonia phage Jumbo, complete genome) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
cgacgttcgacaaaatccgcgatggtattgtc	Protospacer
***********.**** ********.. *

20. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050093 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b5, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcgttcgccgaaatgcgcgatgccgtcaga	Protospacer
 *.****** ************** ** . *.

21. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NC_008384 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcgttcgccgaaatgcgcgatgccgtcaga	Protospacer
 *.****** ************** ** . *.

22. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042332 (Bosea sp. F3-2 plasmid pB32-1, complete sequence) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
aggcggtcgacgaaatgcgcgacggcgtcgtg	Protospacer
 *.** ****************.**** .  *

23. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 8, identity: 0.75

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
ccatattcgccgaattgcgcgatggcggcggc	Protospacer
* *..**** **** *************. *

24. spacer 3.4|3815906|32|NZ_CP008697|CRISPRCasFinder,CRT matches to MN855615 (Siphoviridae sp. isolate 320, complete genome) position: , mismatch: 8, identity: 0.75

tatgcgcttgctgctgcgttgatgtacgcggc	CRISPR spacer
tatgcgcttgctggtgctttgatgggcagtgg	Protospacer
************* *** ****** .*.  *

25. spacer 3.4|3815906|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NC_034248 (Rhizobium phage RHEph10, complete genome) position: , mismatch: 8, identity: 0.75

tatgcgcttgctgctgcgttgatgtacgcggc	CRISPR spacer
tctccttatgctgctgcgttgatggccgcggt	Protospacer
* * * . ****************  *****.

26. spacer 3.9|3816211|33|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 8, identity: 0.758

gcgcggccgcgatatcgttagcactggctcccg	CRISPR spacer
cggcggccgcgatatcgttcgcgctgccgcgcc	Protospacer
  ***************** **.*** * * *

27. spacer 3.13|3816457|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NC_013085 (Synechococcus phage S-RSM4, complete genome) position: , mismatch: 8, identity: 0.75

aatttttccagtggtgtcgttgtaattaagga-----	CRISPR spacer
gatttttccaatgctgtcgttgt-----aggagctac	Protospacer
.*********.** *********     ****

28. spacer 3.13|3816457|32|NZ_CP008697|CRISPRCasFinder,CRT matches to FM207411 (Synechococcus phage S-RSM4 complete genome) position: , mismatch: 8, identity: 0.75

aatttttccagtggtgtcgttgtaattaagga-----	CRISPR spacer
gatttttccaatgctgtcgttgt-----aggagctac	Protospacer
.*********.** *********     ****

29. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_CP053709 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ggacgaagcaggcgcgcggggcgctggcgggg	Protospacer
.*.. **. ******** ********** ***

30. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_CP053710 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ggacgaagcaggcgcgcggggcgctggcgggg	Protospacer
.*.. **. ******** ********** ***

31. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_CP053712 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.75

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ggacgaagcaggcgcgcggggcgctggcgggg	Protospacer
.*.. **. ******** ********** ***

32. spacer 1.2|1755095|32|NZ_CP008697|CRISPRCasFinder matches to NZ_CP045060 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttcactggtaacatactccacccgcccaccat	CRISPR spacer
tgtcctggtaacatgttccacccgcccggtgt	Protospacer
* . **********..***********. ..*

33. spacer 1.2|1755095|32|NZ_CP008697|CRISPRCasFinder matches to NZ_CP045053 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttcactggtaacatactccacccgcccaccat	CRISPR spacer
tgtcctggtaacatgttccacccgcccggtgt	Protospacer
* . **********..***********. ..*

34. spacer 1.2|1755095|32|NZ_CP008697|CRISPRCasFinder matches to NZ_CP045057 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence) position: , mismatch: 9, identity: 0.719

ttcactggtaacatactccacccgcccaccat	CRISPR spacer
tgtcctggtaacatgttccacccgcccggtgt	Protospacer
* . **********..***********. ..*

35. spacer 2.4|3789537|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MN693584 (Marine virus AFVG_25M163, complete genome) position: , mismatch: 9, identity: 0.719

tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
aatataaacgaggtgagtttatagatatcccc	Protospacer
 ***************.*****.** *.. .

36. spacer 2.4|3789537|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MN103543 (Pseudomonas phage vB_PaeM_PS119XW, complete genome) position: , mismatch: 9, identity: 0.719

tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
tccataaccgaggtgaatgtatggaagaagcg	Protospacer
* .**** ********** *******.  *..

37. spacer 2.4|3789537|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MK599315 (Pseudomonas phage PA1C, complete genome) position: , mismatch: 9, identity: 0.719

tatataaacgaggtgaatttatggaaactgta	CRISPR spacer
tccataaccgaggtgaatgtatggaagaagcg	Protospacer
* .**** ********** *******.  *..

38. spacer 2.7|3789721|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to MT446414 (UNVERIFIED: Escherichia virus TH43, complete genome) position: , mismatch: 9, identity: 0.719

ttcgagacacttctctgcaaaattaatgaaat	CRISPR spacer
ataaatttccttctctgcaaagttgatgaaat	Protospacer
 * .*  . ************.**.*******

39. spacer 2.9|3789843|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053709 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

aattgattgctgggtgatattggaaaatgttg	CRISPR spacer
atttgatagctggctgatattggaaggcaatc	Protospacer
* ***** ***** ***********.... *

40. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017077 (Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
ctctcagcgacgaactgcgcgatgccggtcga	Protospacer
*  .   ******* ********* ******.

41. spacer 2.11|3789965|32|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgttcgacgaaatgcgcgatggcggtcgg	CRISPR spacer
atgtgctcgaggaaatgcgcgatgccggtctc	Protospacer
  ..*.**** ************* *****

42. spacer 3.2|3815784|32|NZ_CP008697|CRISPRCasFinder,CRT matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 9, identity: 0.719

aatatccgttcctcgctctgcgttttcgttga	CRISPR spacer
gaaatccgtttctcgctctccgttttgctctt	Protospacer
.* *******.******** ******  *.

43. spacer 3.2|3815784|32|NZ_CP008697|CRISPRCasFinder,CRT matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 9, identity: 0.719

aatatccgttcctcgctctgcgttttcgttga	CRISPR spacer
gaaatccgtttctcgctctccgttttgctctt	Protospacer
.* *******.******** ******  *.

44. spacer 3.6|3816028|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_CP016721 (Lactococcus lactis subsp. lactis strain UC11 plasmid pUC11B, complete sequence) position: , mismatch: 9, identity: 0.719

gattcaatgtccgacgcatccaagtaaatatt	CRISPR spacer
ctttcaatgtcctacgcattcaagtcatgaaa	Protospacer
  ********** ******.***** *  *

45. spacer 3.6|3816028|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_CP016727 (Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08B, complete sequence) position: , mismatch: 9, identity: 0.719

gattcaatgtccgacgcatccaagtaaatatt	CRISPR spacer
ctttcaatgtcctacgcattcaagtcatgaaa	Protospacer
  ********** ******.***** *  *

46. spacer 3.12|3816396|32|NZ_CP008697|CRISPRCasFinder,CRT matches to MW084976 (Bacillus phage Kirov, complete genome) position: , mismatch: 9, identity: 0.719

tgactgaccgggaaaagaaaacacctggcgaa	CRISPR spacer
ttatagactgggaaaagaaaacacttggaatt	Protospacer
* *. ***.***************.*** .

47. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to JX469828 (Uncultured bacterium plasmid pRSB223, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccgctaaagaggcgcgcaaggcgctggaggcc	Protospacer
  *.************* .********  *

48. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to JX469829 (Uncultured bacterium plasmid pB1, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccgctaaagaggcgcgcaaggcgctggaggcc	Protospacer
  *.************* .********  *

49. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
tgatggctgaggcgcgccgggcgctgcccggc	Protospacer
 *.* .  ****************** *.**

50. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NC_008766 (Acidovorax sp. JS42 plasmid pAOVO02, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccgctaaagaggcgcgcaaggcgctggaggcc	Protospacer
  *.************* .********  *

51. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
catgtgaagcggcgcgccgggcgcgggctccg	Protospacer
 .  *.*** ************** ****  *

52. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NZ_MN366361 (Bacterium plasmid pALTS33, complete sequence) position: , mismatch: 9, identity: 0.719

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccgctaaagaggcgcgcaaggcgctggaggcc	Protospacer
  *.************* .********  *

53. spacer 3.24|3815906|33|NZ_CP008697|PILER-CR matches to MN855615 (Siphoviridae sp. isolate 320, complete genome) position: , mismatch: 9, identity: 0.727

tatgcgcttgctgctgcgttgatgtacgcggcc	CRISPR spacer
tatgcgcttgctggtgctttgatgggcagtggt	Protospacer
************* *** ****** .*.  * .

54. spacer 3.29|3816211|34|NZ_CP008697|PILER-CR matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 9, identity: 0.735

gcgcggccgcgatatcgttagcactggctcccgc	CRISPR spacer
cggcggccgcgatatcgttcgcgctgccgcgccg	Protospacer
  ***************** **.*** * * *

55. spacer 2.5|3789598|33|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 10, identity: 0.697

gttagttttctgaaaaaaattgttttcttacgc	CRISPR spacer
tctccttttcttaaaaatattgttttcttttaa	Protospacer
 .*  ****** ***** *********** ..

56. spacer 3.14|3816518|32|NZ_CP008697|CRISPRCasFinder,CRT matches to NC_004929 (Ruegeria sp. PR1b plasmid pSD20, complete sequence) position: , mismatch: 10, identity: 0.688

aggttaaagaggcgcgccgggcgctggctggg	CRISPR spacer
ccctctggcaggcgcgccgggcgcaggcgggg	Protospacer
   *. .. *************** *** ***

57. spacer 2.5|3789598|33|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NC_011260 (Borrelia recurrentis A1 plasmid pl53, complete sequence) position: , mismatch: 11, identity: 0.667

gttagttttctgaaaaaaattgttttcttacgc	CRISPR spacer
aaatcttttctataaaaaattgttttctttata	Protospacer
.    ******. ****************

58. spacer 2.5|3789598|33|NZ_CP008697|CRISPRCasFinder,CRT,PILER-CR matches to NC_011260 (Borrelia recurrentis A1 plasmid pl53, complete sequence) position: , mismatch: 11, identity: 0.667

gttagttttctgaaaaaaattgttttcttacgc	CRISPR spacer
aaatcttttctataaaaaattgttttctttata	Protospacer
.    ******. ****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

271593 : 396769

127

Enterobacteria_phage(23.29%)

portal,terminase,head,tRNA,integrase,lysis,tail,protease,holin,capsid,plate,transposase

attL 374941:374956|attR 396193:396208

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000187016.1\|271593_272694_-\|tRNA	tRNA (uridine(54)-C5)-methyltransferase TrmA	NA	NA	NA	NA
WP_016235454.1\|273062_274907_+	TonB-dependent vitamin B12 receptor BtuB	A0A0P0I887	Acinetobacter_phage	5.5e-10	32.6
WP_000201825.1\|274851_275709_+	glutamate racemase	NA	NA	NA	NA
WP_000236980.1\|281214_281658_-	acetyltransferase	NA	NA	NA	NA
WP_001122786.1\|281814_282744_+	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_022646399.1\|283012_284614_+	malate synthase A	NA	NA	NA	NA
WP_000857856.1\|284643_285948_+	isocitrate lyase	NA	NA	NA	NA
WP_022646400.1\|286033_287758_+	bifunctional isocitrate dehydrogenase kinase/phosphatase	NA	NA	NA	NA
WP_000226403.1\|287774_288599_-	glyoxylate bypass operon transcriptional repressor IclR	NA	NA	NA	NA
WP_001572176.1\|288798_292482_+	methionine synthase	A0A140XBC7	Dickeya_phage	1.3e-26	90.2
WP_000956822.1\|292701_294333_+	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_022646401.1\|294422_295112_-	dipeptidase PepE	NA	NA	NA	NA
WP_000610344.1\|295234_296047_-	shikimate 5-dehydrogenase	NA	NA	NA	NA
WP_000858564.1\|296039_297269_-	L-sorbose 1-phosphate reductase	NA	NA	NA	NA
WP_022646402.1\|297320_298145_-	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_000406332.1\|298155_298953_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_001027853.1\|299018_299513_-	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_000245629.1\|299512_299920_-	PTS sorbose transporter subunit IIA	NA	NA	NA	NA
WP_001195407.1\|299929_300736_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000431660.1\|300805_301753_-	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_060684344.1\|302100_303039_+	23S rRNA pseudouridine(2604) synthase RluF	NA	NA	NA	NA
WP_001207638.1\|302972_303245_-	DUF3811 domain-containing protein	NA	NA	NA	NA
WP_022646404.1\|303773_304901_+	slipin family protein	NA	NA	NA	NA
WP_022646405.1\|304906_305698_+	nucleotidyltransferase domain-containing protein	A0A2D1GQQ2	Pseudomonas_phage	2.0e-46	45.1
WP_022646406.1\|305711_306167_-	hypothetical protein	F6MIM0	Haemophilus_phage	6.6e-26	42.7
WP_022646407.1\|306163_306871_-	DUF4376 domain-containing protein	A0A0E3JQ06	Enterobacteria_phage	5.3e-14	42.4
WP_022646408.1\|306867_308478_-\|tail	phage tail protein	A0A0M3ULH6	Salmonella_phage	3.8e-84	39.1
WP_060684345.1\|308480_309197_-\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	7.0e-22	37.2
WP_022646410.1\|309189_310305_-\|plate	baseplate J/gp47 family protein	Q6QI99	Burkholderia_phage	2.0e-100	51.7
WP_022646411.1\|310295_310655_-	GPW/gp25 family protein	Q6QIA0	Burkholderia_phage	1.1e-34	64.2
WP_000679403.1\|310753_311455_-\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	6.4e-12	36.3
WP_022646412.1\|311464_312505_-	phage late control D family protein	A4JWL3	Burkholderia_virus	2.0e-73	45.1
WP_001269711.1\|312492_312702_-\|tail	tail protein X	A4JWL2	Burkholderia_virus	1.3e-16	60.3
WP_022646413.1\|312701_313655_-\|tail	phage tail protein	A4JWL1	Burkholderia_virus	3.3e-35	50.8
WP_015674804.1\|316132_316261_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_022646415.1\|316220_316538_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_000907502.1\|316588_317113_-\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	9.5e-69	69.0
WP_022646416.1\|317112_318537_-\|tail	phage tail sheath family protein	A4JWK5	Burkholderia_virus	7.0e-191	70.2
WP_000875310.1\|318526_318724_-	hypothetical protein	NA	NA	NA	NA
WP_022646417.1\|318720_319176_-	hypothetical protein	NA	NA	NA	NA
WP_000777272.1\|319320_319635_-	membrane protein	Q5ZQY8	Pseudomonas_phage	9.2e-19	43.2
WP_000266448.1\|319647_320253_-	lytic transglycosylase domain-containing protein	Q5ZQZ1	Pseudomonas_phage	3.3e-57	57.1
WP_022646418.1\|320255_320543_-\|holin	putative holin	Q6QIC8	Burkholderia_phage	3.9e-16	48.6
WP_000619864.1\|321080_321428_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	2.2e-21	49.0
WP_013362812.1\|323193_324162_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.6e-186	100.0
WP_001617865.1\|324196_325072_-	class A extended-spectrum beta-lactamase CTX-M-14	A0A1B0VBP7	Salmonella_phage	6.1e-153	99.6
WP_000608644.1\|325321_326584_-\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_022646420.1\|327522_329172_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_000757333.1\|329526_329769_+	polysaccharide production threonine-rich protein	NA	NA	NA	NA
WP_001296632.1\|329882_330521_+	YjbF family lipoprotein	NA	NA	NA	NA
WP_060684348.1\|330517_331255_+	capsule biosynthesis GfcC family protein	NA	NA	NA	NA
WP_001295279.1\|333399_333678_-	periplasmic protein	NA	NA	NA	NA
WP_000202902.1\|333891_334302_+	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
WP_001252058.1\|334395_335286_-	maltose ABC transporter permease MalG	NA	NA	NA	NA
WP_022646423.1\|335300_336845_-	maltose ABC transporter permease MalF	NA	NA	NA	NA
WP_000695389.1\|336998_338189_-	maltose/maltodextrin ABC transporter substrate-binding protein MalE	NA	NA	NA	NA
WP_000179165.1\|338553_339669_+	maltose/maltodextrin ABC transporter ATP-binding protein MalK	Q6GZ03	Mycoplasma_phage	4.3e-18	31.7
WP_000973665.1\|339740_341081_+	maltoporin LamB	NA	NA	NA	NA
WP_000783444.1\|341232_342153_+	maltose operon protein MalM	NA	NA	NA	NA
WP_022646424.1\|342380_343961_+	SopA family protein	NA	NA	NA	NA
WP_001308201.1\|344183_344681_+	chorismate lyase	NA	NA	NA	NA
WP_000455227.1\|344693_345566_+	4-hydroxybenzoate octaprenyltransferase	NA	NA	NA	NA
WP_000017354.1\|345720_348144_-	glycerol-3-phosphate 1-O-acyltransferase PlsB	NA	NA	NA	NA
WP_000002907.1\|348314_348683_+	diacylglycerol kinase	NA	NA	NA	NA
WP_000646078.1\|348792_349401_+	repressor LexA	Q9G0C2	Lactococcus_phage	1.0e-13	38.0
WP_001361471.1\|349473_350799_+	MATE family efflux transporter DinF	NA	NA	NA	NA
WP_001296638.1\|350914_351124_+	CsbD family protein	NA	NA	NA	NA
WP_000416263.1\|351165_351681_-	zinc uptake transcriptional repressor Zur	NA	NA	NA	NA
WP_022646425.1\|351998_353003_+	DUF2713 family protein	NA	NA	NA	NA
WP_001300034.1\|353364_353487_+	hypothetical protein	NA	NA	NA	NA
WP_060684349.1\|353722_354295_+	SocA family protein	NA	NA	NA	NA
WP_014640052.1\|354324_354711_+	hypothetical protein	NA	NA	NA	NA
WP_023908888.1\|354750_354924_+	hypothetical protein	K7PJQ2	Enterobacteria_phage	1.4e-21	94.7
WP_001093916.1\|354971_355253_-	pyocin activator PrtN family protein	K7PGU0	Enterobacteria_phage	2.8e-43	96.8
WP_024946495.1\|355289_356042_-	hypothetical protein	NA	NA	NA	NA
WP_023908886.1\|356260_357085_-	DUF2303 family protein	U5P439	Shigella_phage	3.0e-149	99.6
WP_000135686.1\|357150_357513_-	hypothetical protein	Q8SBF8	Shigella_phage	1.5e-60	99.2
WP_021530636.1\|358180_358855_-	LexA family transcriptional regulator	Q8SBF6	Shigella_phage	3.5e-132	100.0
WP_021527487.1\|358945_359146_+	helix-turn-helix domain-containing protein	U5P445	Shigella_phage	1.3e-31	98.5
WP_024946496.1\|359189_359747_+	hypothetical protein	K7PGU3	Enterobacteria_phage	1.0e-92	93.5
WP_071789194.1\|359922_360102_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	4.6e-15	68.5
WP_023908882.1\|360091_361033_+	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	3.2e-139	92.3
WP_023908881.1\|361029_361518_+	PerC family transcriptional regulator	A0A0P0ZCF0	Stx2-converting_phage	8.6e-80	93.2
WP_001401088.1\|361517_362171_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	3.3e-127	99.1
WP_000210154.1\|362167_362494_+	LexA family transcriptional regulator	A0A0N7KZF7	Stx2-converting_phage	2.7e-53	99.1
WP_000767133.1\|362490_362880_+	RusA family crossover junction endodeoxyribonuclease	A5LH74	Enterobacteria_phage	1.6e-68	99.2
WP_023908880.1\|362899_363709_+	KilA-N domain-containing protein	A5LH75	Enterobacteria_phage	8.2e-152	99.6
WP_023908878.1\|364720_365473_+	antitermination protein	K7PGU5	Enterobacteria_phage	4.2e-134	97.2
WP_001181554.1\|365665_365869_+	hypothetical protein	NA	NA	NA	NA
WP_024946499.1\|365998_366334_+\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	2.5e-54	93.7
WP_021543581.1\|366337_366814_+	glycoside hydrolase family protein	K7PKV2	Enterobacteria_phage	6.2e-83	94.3
WP_023908876.1\|366810_367254_+\|lysis	lysis protein	M1FJ79	Enterobacteria_phage	2.3e-71	94.6
WP_021543580.1\|367292_367667_+	hypothetical protein	M1FPD9	Enterobacteria_phage	1.8e-61	96.0
WP_000699783.1\|367784_367988_+	hypothetical protein	A0A1W6JPG4	Morganella_phage	4.9e-13	52.9
WP_024946501.1\|368053_368404_+	HNH endonuclease	M1FQV2	Enterobacteria_phage	1.2e-62	96.6
WP_000929184.1\|368530_369025_+\|terminase	phage terminase small subunit P27 family	U5P067	Shigella_phage	2.3e-88	100.0
WP_065312442.1\|369258_370755_+\|terminase	terminase large subunit	A0A1C9IIA1	Salmonella_phage	1.7e-299	99.6
WP_000605605.1\|370766_370949_+	hypothetical protein	S5FXQ9	Shigella_phage	3.8e-25	98.3
WP_023908874.1\|370948_372190_+\|portal	phage portal protein	U5P411	Shigella_phage	2.9e-241	99.0
WP_001193633.1\|372167_372818_+\|head,protease	HK97 family phage prohead protease	U5P4H2	Shigella_phage	7.3e-119	99.5
WP_023908873.1\|372832_374038_+\|capsid	phage major capsid protein	A0A1B5FPI9	Escherichia_phage	1.7e-222	99.0
WP_023908872.1\|374087_374276_+	hypothetical protein	A0A1B5FP98	Escherichia_phage	8.8e-25	93.5
WP_021543573.1\|374287_374593_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B5FP86	Escherichia_phage	3.9e-38	87.1
WP_021543572.1\|374602_374941_+\|head	phage head closure protein	A0A1B5FP90	Escherichia_phage	4.6e-48	84.8
WP_021543571.1\|374937_375387_+	HK97 gp10 family phage protein	S4TR46	Salmonella_phage	1.3e-61	78.5
374941:374956	attL	NA	NA	NA	NA
WP_021543570.1\|375383_375728_+	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	1.9e-54	94.7
WP_023908871.1\|375787_376492_+	immunoglobulin domain-containing protein	A0A1B5FP82	Escherichia_phage	1.8e-110	90.6
WP_021543568.1\|376506_376878_+\|tail	phage tail assembly chaperone	A0A1B5FP91	Escherichia_phage	3.1e-58	90.2
WP_021543567.1\|376901_377180_+	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	1.5e-33	80.4
WP_021543566.1\|377238_377580_+	zinc ribbon domain-containing protein	S4TR42	Salmonella_phage	7.6e-35	64.5
WP_024946502.1\|377624_380867_+\|tail	phage tail tape measure protein	A0A1B5FPE2	Escherichia_phage	0.0e+00	88.8
WP_023908869.1\|380859_381201_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	7.9e-40	66.4
WP_021543563.1\|381200_381899_+\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	1.8e-131	98.3
WP_032152077.1\|381903_382647_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	4.4e-152	99.2
WP_000741576.1\|382544_383192_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.7e-113	98.6
WP_060684350.1\|383252_386732_+	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	90.0
WP_001228252.1\|386799_387399_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	3.4e-102	92.5
WP_022646430.1\|387463_389812_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A0E3M0V5	Enterobacteria_phage	9.5e-92	46.3
WP_022646431.1\|389808_390090_+	hypothetical protein	A0A1X7QHA1	Escherichia_phage	4.1e-18	50.0
WP_001595444.1\|390099_390804_+\|tail	tail fiber domain-containing protein	A0A1X7QGH6	Escherichia_phage	7.0e-59	61.7
WP_022646432.1\|390814_391102_+	hypothetical protein	NA	NA	NA	NA
WP_001217539.1\|391212_391461_-	DinI-like family protein	A5LH55	Enterobacteria_phage	1.1e-38	100.0
WP_000332260.1\|391522_392620_-\|integrase	site-specific integrase	S5MDN5	Escherichia_phage	4.0e-210	99.2
WP_000543825.1\|392708_393746_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_000891408.1\|393879_394122_+	envelope stress response protein PspG	NA	NA	NA	NA
WP_022646433.1\|394287_395271_-	quinone oxidoreductase	NA	NA	NA	NA
WP_000918363.1\|395353_396769_+	replicative DNA helicase	O80281	Escherichia_phage	4.8e-200	78.3
396193:396208	attR	NA	NA	NA	NA

DBSCAN-SWA_2

479992 : 499135

Burkholderia_phage(27.27%)

tail,holin,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022646456.1\|479992_481510_-\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	1.2e-87	38.0
WP_022646457.1\|481746_483204_-	dipeptide/tripeptide permease DtpC	A0A0P0IY73	Acinetobacter_phage	4.0e-48	29.6
WP_001296667.1\|483262_485410_-	lysine decarboxylase CadA	NA	NA	NA	NA
WP_000092909.1\|485489_486824_-	cadaverine/lysine antiporter	NA	NA	NA	NA
WP_015674804.1\|488681_488810_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_022646415.1\|488769_489087_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_000907502.1\|489137_489662_-\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	9.5e-69	69.0
WP_022646416.1\|489661_491086_-\|tail	phage tail sheath family protein	A4JWK5	Burkholderia_virus	7.0e-191	70.2
WP_000875310.1\|491075_491273_-	hypothetical protein	NA	NA	NA	NA
WP_022646417.1\|491269_491725_-	hypothetical protein	NA	NA	NA	NA
WP_000777272.1\|491869_492184_-	membrane protein	Q5ZQY8	Pseudomonas_phage	9.2e-19	43.2
WP_060684353.1\|492196_492802_-	lytic transglycosylase domain-containing protein	Q5ZQZ1	Pseudomonas_phage	3.3e-57	56.1
WP_022646418.1\|492806_493094_-\|holin	putative holin	Q6QIC8	Burkholderia_phage	3.9e-16	48.6
WP_000619864.1\|493631_493979_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	2.2e-21	49.0
WP_013362812.1\|495744_496713_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.6e-186	100.0
WP_001617865.1\|496747_497623_-	class A extended-spectrum beta-lactamase CTX-M-14	A0A1B0VBP7	Salmonella_phage	6.1e-153	99.6
WP_000608644.1\|497872_499135_-\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0

DBSCAN-SWA_3

601913 : 673386

Vibrio_phage(12.5%)

protease,holin,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060684359.1\|601913_603266_+\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_001232240.1\|603448_603835_+	cytochrome b562	NA	NA	NA	NA
WP_060684360.1\|603879_604344_-	anaerobic ribonucleoside-triphosphate reductase-activating protein	K4F9T1	Cronobacter_phage	1.1e-52	56.4
WP_000187778.1\|604501_606640_-	anaerobic ribonucleoside-triphosphate reductase	A0A2I7QNQ7	Vibrio_phage	1.5e-266	64.5
WP_001339491.1\|607033_608689_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_001299664.1\|608738_610160_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_001181324.1\|610278_611226_-	HTH-type transcriptional regulator TreR	C6ZCU4	Enterobacteria_phage	7.9e-13	21.8
WP_001387276.1\|611410_611464_+	mgtA regulatory leader peptide MgtL	NA	NA	NA	NA
WP_000471889.1\|611603_614300_+	magnesium-translocating P-type ATPase	M1HLC0	Paramecium_bursaria_Chlorella_virus	9.0e-46	27.4
WP_000047538.1\|614505_614892_-	2-iminobutanoate/2-iminopropanoate deaminase	NA	NA	NA	NA
WP_000148581.1\|614964_615426_-	aspartate carbamoyltransferase regulatory subunit	NA	NA	NA	NA
WP_000013046.1\|615438_616374_-	aspartate carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	2.9e-52	40.2
WP_001296693.1\|616377_616512_-	pyr operon leader peptide	NA	NA	NA	NA
WP_000230277.1\|616792_617188_-	RidA family protein	NA	NA	NA	NA
WP_000500725.1\|617318_618032_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000256670.1\|618102_618696_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001353502.1\|618840_619293_+	toxin-antitoxin biofilm protein TabA	NA	NA	NA	NA
WP_024946506.1\|619415_620999_+	DNA-binding protein	NA	NA	NA	NA
WP_023908892.1\|621166_622180_-	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_000002953.1\|622341_622758_+	ribonuclease E inhibitor RraB	NA	NA	NA	NA
WP_001059402.1\|622902_623406_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_023908893.1\|623597_624794_+	DUF898 domain-containing protein	NA	NA	NA	NA
WP_060684361.1\|624849_627705_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	3.3e-139	36.4
WP_000786399.1\|627704_628148_-	DNA polymerase III subunit chi	NA	NA	NA	NA
WP_000397144.1\|628406_629918_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	6.0e-47	38.0
WP_000584117.1\|630184_631285_+	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_001295681.1\|631284_632367_+	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_001514874.1\|632527_634030_-	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	7.9e-84	44.6
WP_001300770.1\|634159_635179_-	NADPH-dependent aldehyde reductase Ahr	A0A0G2Y405	Acanthamoeba_polyphaga_mimivirus	1.4e-44	30.7
WP_000908169.1\|635972_636887_-	hypothetical protein	NA	NA	NA	NA
WP_000190110.1\|637862_638423_+	recombinase family protein	A0A219Y912	Aeromonas_phage	4.2e-22	39.9
WP_000331918.1\|638436_639282_+	hypothetical protein	NA	NA	NA	NA
WP_001724296.1\|639342_639837_-	hypothetical protein	NA	NA	NA	NA
WP_000749342.1\|640077_640542_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001064798.1\|644070_644835_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_016246833.1\|645074_645974_+	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_001044501.1\|645990_647508_+	altronate dehydratase	NA	NA	NA	NA
WP_024946607.1\|647585_648593_+	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_024946608.1\|648894_650160_+	MFS transporter	NA	NA	NA	NA
WP_032152090.1\|650169_651126_+	amidohydrolase family protein	NA	NA	NA	NA
WP_060684362.1\|651707_652718_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	3.6e-197	99.4
WP_000839179.1\|653254_653659_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_000612626.1\|653655_654003_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_001741392.1\|655653_656787_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000916805.1\|659028_659472_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_001741394.1\|659487_659775_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_000345347.1\|659787_661044_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_001305336.1\|661290_661482_-\|transposase	transposase	Q6H9S5	Enterobacteria_phage	8.3e-15	65.6
WP_004019923.1\|661966_662980_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_000998346.1\|662991_664308_-	L-fucose:H+ symporter permease	NA	NA	NA	NA
WP_000350265.1\|664335_665256_-	ribokinase	NA	NA	NA	NA
WP_001295538.1\|665561_666344_+	DeoR family transcriptional regulator	NA	NA	NA	NA
WP_001296706.1\|667542_667671_+	alcohol dehydrogenase	NA	NA	NA	NA
WP_000145475.1\|667851_668508_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001375347.1\|668755_670033_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_001293435.1\|670095_672093_-\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	7.4e-21	25.9
WP_000088351.1\|672246_673386_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	7.9e-68	44.7

DBSCAN-SWA_4

987108 : 1052933

Emiliania_huxleyi_virus(11.11%)

plate,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022645195.1\|987108_988461_+\|protease	sigma E protease regulator RseP	NA	NA	NA	NA
WP_001240896.1\|988490_990923_+	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_000758956.1\|991044_991530_+	molecular chaperone Skp	NA	NA	NA	NA
WP_001139282.1\|991533_992559_+	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
WP_000210739.1\|992663_993119_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_000565966.1\|993122_993911_+	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_022645196.1\|993910_995059_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_022645197.1\|995055_995652_+	ribonuclease HII	V5LS49	Emiliania_huxleyi_virus	2.3e-26	40.0
WP_001294757.1\|995688_999171_+	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	2.2e-209	36.9
WP_000055746.1\|999183_1000143_+	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
WP_001020966.1\|1000241_1002383_+	lysine decarboxylase LdcC	NA	NA	NA	NA
WP_000901098.1\|1002439_1002829_+	VOC family protein	NA	NA	NA	NA
WP_022645198.1\|1002893_1004192_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_000062318.1\|1004240_1004501_-	Rho-binding antiterminator	NA	NA	NA	NA
WP_000417058.1\|1004487_1004688_-	YaeP family protein	NA	NA	NA	NA
WP_001185283.1\|1004853_1005399_+	YaeQ family protein	NA	NA	NA	NA
WP_000635528.1\|1005395_1005818_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000239184.1\|1005831_1006542_+	envelope stress response activation lipoprotein NlpE	NA	NA	NA	NA
WP_022645199.1\|1006697_1007522_-	YaeF family permuted papain-like enzyme	NA	NA	NA	NA
WP_022645200.1\|1007574_1009293_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_000094006.1\|1009403_1010111_-\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_001202329.1\|1010107_1010512_-	Rcs stress response system protein RcsF	NA	NA	NA	NA
WP_000874226.1\|1010629_1011445_-	methionine ABC transporter substrate-binding lipoprotein MetQ	NA	NA	NA	NA
WP_001294600.1\|1011484_1012138_-	methionine ABC transporter permease MetI	NA	NA	NA	NA
WP_000593991.1\|1012130_1013162_-	methionine ABC transporter ATP-binding protein MetN	G9BWD6	Planktothrix_phage	7.2e-36	40.2
WP_022645201.1\|1019692_1020496_+	2,5-didehydrogluconate reductase DkgB	A0A1V0SDE7	Indivirus	2.7e-38	35.8
WP_000648568.1\|1020492_1021407_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_001230983.1\|1021647_1022448_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_000211702.1\|1022524_1023295_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000644685.1\|1023342_1024701_-	murein transglycosylase D	A0A2H4J9N7	uncultured_Caudovirales_phage	5.8e-09	36.0
WP_001052732.1\|1024772_1025528_-	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_001308373.1\|1025561_1026284_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000917883.1\|1026280_1026748_-	ribonuclease HI	J9Q745	Salmonella_phage	1.0e-50	58.7
WP_001308374.1\|1026812_1027544_+	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	7.6e-40	38.6
WP_022645202.1\|1028078_1028864_+	hypothetical protein	NA	NA	NA	NA
WP_022645204.1\|1029494_1030403_-	hypothetical protein	NA	NA	NA	NA
WP_022645205.1\|1030446_1030929_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_022645206.1\|1030952_1032305_-	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_122988716.1\|1032315_1035750_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_022645208.1\|1035858_1037274_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_022645209.1\|1037278_1038022_-	type VI secretion system-associated protein TagO	NA	NA	NA	NA
WP_022645210.1\|1038018_1040778_-	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	7.2e-83	29.0
WP_022645211.1\|1040786_1041548_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_022645212.1\|1041552_1042884_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_001080149.1\|1042886_1043411_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_001113710.1\|1043407_1044688_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_022645213.1\|1044712_1045795_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_022645214.1\|1045758_1047609_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_022645215.1\|1047612_1048026_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_060684380.1\|1048032_1049508_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_022645217.1\|1049558_1049783_-	hypothetical protein	NA	NA	NA	NA
WP_000037391.1\|1049817_1050318_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_001142958.1\|1051014_1051533_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_085949836.1\|1051719_1052933_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	4.7e-103	58.4

DBSCAN-SWA_5

1332304 : 1422576

Enterobacteria_phage(56.36%)

terminase,head,tRNA,integrase,lysis,tail,protease,capsid,transposase

attL 1342456:1342502|attR 1389160:1389206

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000912345.1\|1332304_1333690_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.9e-45	34.8
WP_001143564.1\|1333725_1334247_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_000190288.1\|1334354_1334567_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_000729155.1\|1334568_1335435_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
WP_000776555.1\|1335906_1336449_+	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
WP_022645303.1\|1336668_1337361_+	type 1 fimbria chaperone FimC	NA	NA	NA	NA
WP_022645304.1\|1337391_1340001_+	fimbrial biogenesis usher protein	NA	NA	NA	NA
WP_000691076.1\|1340013_1341021_+	type 1 fimbrin D-mannose specific adhesin FimH	NA	NA	NA	NA
WP_001255235.1\|1341031_1341547_+	fimbria assembly protein	NA	NA	NA	NA
WP_060684390.1\|1341549_1342182_-	fimbria biosynthesis transcriptional regulator FimZ	NA	NA	NA	NA
1342456:1342502	attL	NA	NA	NA	NA
WP_001299447.1\|1342515_1343679_-\|integrase	site-specific integrase	A0A088CD23	Shigella_phage	3.4e-199	86.3
WP_000488407.1\|1343877_1344156_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.9e-48	97.8
WP_022645305.1\|1344203_1344422_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	5.4e-34	97.2
WP_000548537.1\|1344813_1345005_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
WP_000149544.1\|1344977_1345160_-	DUF1317 domain-containing protein	A0A1U8QQC1	Enterobacteria_phage	6.9e-27	96.7
WP_000186848.1\|1345156_1345837_-	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	1.6e-132	100.0
WP_023909022.1\|1345833_1346619_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	1.5e-147	98.9
WP_020241285.1\|1346624_1346921_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	3.6e-49	99.0
WP_000233579.1\|1346997_1347204_-	hypothetical protein	K7PM31	Enterobacteria_phage	7.1e-28	83.8
WP_000858975.1\|1347798_1348488_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	2.8e-92	75.0
WP_001067458.1\|1348592_1348823_+	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
WP_001182772.1\|1348892_1349432_+	toxin YdaT domain-containing protein	M9NZI6	Enterobacteria_phage	1.5e-61	66.1
WP_000147901.1\|1349428_1350448_+	replication protein	A0A0M5M7Y1	Salmonella_phage	4.4e-110	63.8
WP_000788890.1\|1350444_1351146_+	Replication protein P	M1FJ72	Enterobacteria_phage	7.9e-127	97.4
WP_000145902.1\|1351142_1351445_+	hypothetical protein	A0A0N6WES4	Escherichia_phage	1.7e-41	93.5
WP_001070451.1\|1351512_1351845_+	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_032139864.1\|1351936_1352044_+	hypothetical protein	NA	NA	NA	NA
WP_000709074.1\|1352101_1353628_+	recombinase family protein	Q3HQV4	Burkholderia_phage	3.6e-31	27.7
WP_001351655.1\|1353739_1354063_+	hypothetical protein	NA	NA	NA	NA
WP_000379700.1\|1354524_1354881_+	hypothetical protein	NA	NA	NA	NA
WP_072130332.1\|1354970_1355072_+	hypothetical protein	NA	NA	NA	NA
WP_001053034.1\|1355068_1355524_+	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	4.9e-61	67.5
WP_000224912.1\|1355523_1355694_+	hypothetical protein	K7P7K0	Enterobacteria_phage	1.4e-13	69.8
WP_000774504.1\|1355686_1355977_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.8e-46	92.7
WP_001099712.1\|1355973_1356336_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	4.3e-60	96.5
WP_000971074.1\|1356332_1356473_+	YlcG family protein	K7PHH3	Enterobacteria_phage	6.5e-09	69.8
WP_022645308.1\|1356558_1356936_+	antitermination protein Q	Q777W5	Enterobacteria_phage	8.1e-54	83.3
WP_000780581.1\|1357091_1357616_-	lipocalin family protein	A0A1W6JNX6	Morganella_phage	1.1e-48	54.1
WP_000592546.1\|1357808_1358768_+	DUF523 and DUF1722 domain-containing protein	NA	NA	NA	NA
WP_022645309.1\|1359119_1359851_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000839582.1\|1360038_1360254_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	1.2e-33	98.6
WP_001135261.1\|1360253_1360751_+	lysozyme RrrD	A0A1B5FP97	Escherichia_phage	4.2e-90	97.6
WP_000092273.1\|1360747_1361215_+\|lysis	lysis protein	A0A2D1GLQ7	Escherichia_phage	1.6e-75	96.8
WP_001139678.1\|1361202_1361355_+	hypothetical protein	K7PKL2	Enterobacteria_phage	3.1e-20	96.0
WP_000079508.1\|1361706_1362117_-	DUF1398 family protein	C6ZCX4	Enterobacteria_phage	1.3e-52	76.3
WP_000105084.1\|1362173_1362407_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.3e-21	94.4
WP_000453580.1\|1362795_1363341_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.8e-95	100.0
WP_060684391.1\|1363315_1365241_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.5
WP_000198149.1\|1365237_1365444_+	gpW family protein	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_022645310.1\|1367021_1368341_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	6.9e-233	98.2
WP_001297109.1\|1368350_1368683_+\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	2.2e-55	100.0
WP_022645311.1\|1368738_1369764_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.0e-191	99.4
WP_000158919.1\|1369805_1370204_+	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.1e-64	100.0
WP_000752979.1\|1370215_1370569_+\|head,tail	head-tail joining protein	A0A0K2FJB7	Enterobacteria_phage	2.0e-62	100.0
WP_000985119.1\|1370580_1371159_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	99.5
WP_000683105.1\|1371155_1371551_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.0e-70	100.0
WP_001547245.1\|1371558_1372299_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	1.7e-127	95.9
WP_001468358.1\|1372314_1372737_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.8e-71	97.9
WP_022645312.1\|1372718_1373153_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	1.5e-64	99.2
WP_000847321.1\|1375704_1376034_+\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	8.9e-57	97.2
WP_001152639.1\|1376033_1376732_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.3e-134	100.0
WP_071932122.1\|1376737_1377823_+	Mov34/MPN/PAD-1 family protein	K7PLW1	Enterobacteria_phage	2.8e-115	97.4
WP_023909233.1\|1377883_1381363_+	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	89.6
WP_038431964.1\|1381430_1382030_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	4.4e-102	92.5
WP_060684392.1\|1382094_1384452_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A1X7QGG5	Escherichia_phage	2.2e-117	50.1
WP_001204892.1\|1384451_1384721_+	hypothetical protein	NA	NA	NA	NA
WP_022645319.1\|1384733_1385774_+\|tail	tail fiber domain-containing protein	A0A0E3M4A9	Enterobacteria_phage	2.1e-176	91.9
WP_000386784.1\|1386784_1387534_+	DNA-binding transcriptional activator AppY	NA	NA	NA	NA
WP_001201842.1\|1387782_1388736_-\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_001177457.1\|1389248_1390010_-	DNA-binding transcriptional regulator EnvY	NA	NA	NA	NA
1389160:1389206	attR	NA	NA	NA	NA
WP_022645321.1\|1390192_1391083_-	DUF4434 family protein	NA	NA	NA	NA
WP_022645322.1\|1391083_1394056_-	bacteriophage adsorption protein NfrA	NA	NA	NA	NA
WP_022645323.1\|1394042_1396280_-	phage adsorption protein NrfB	NA	NA	NA	NA
WP_022645326.1\|1398468_1398858_-	hypothetical protein	NA	NA	NA	NA
WP_001160804.1\|1403728_1404190_-	DcrB-related protein	NA	NA	NA	NA
WP_000103215.1\|1404217_1406119_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	6.0e-28	26.1
WP_022645328.1\|1406859_1408308_-	Cu(+)/Ag(+) sensor histidine kinase CusS	A0A1V0SGX0	Hokovirus	2.3e-11	26.1
WP_000770953.1\|1408297_1408981_-	copper response regulator transcription factor CusR	W8CYM9	Bacillus_phage	1.0e-30	35.1
WP_022645329.1\|1409137_1410520_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC	NA	NA	NA	NA
WP_000709873.1\|1410543_1410876_+	Cu(+)/Ag(+) efflux RND transporter periplasmic metallochaperone CusF	NA	NA	NA	NA
WP_022645330.1\|1410891_1412115_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit CusB	NA	NA	NA	NA
WP_022645331.1\|1412126_1415270_+	Cu(+)/Ag(+) efflux RND transporter permease subunit CusA	S5VTK5	Leptospira_phage	5.7e-60	22.4
WP_000786307.1\|1415371_1416748_+	phenylalanine transporter	NA	NA	NA	NA
WP_060684395.1\|1416815_1418063_-	mechanosensitive ion channel YbdG	NA	NA	NA	NA
WP_000351480.1\|1418170_1418824_-	oxygen-insensitive NAD(P)H nitroreductase	NA	NA	NA	NA
WP_000360950.1\|1418902_1419286_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_000682524.1\|1419350_1419599_-	DUF1158 domain-containing protein	NA	NA	NA	NA
WP_022645332.1\|1419664_1420783_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_000956465.1\|1421234_1421387_+	type I toxin-antitoxin system toxin HokE	NA	NA	NA	NA
WP_001300563.1\|1421463_1422576_+\|transposase	IS4-like element IS421 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2140581 : 2226632

Enterobacteria_phage(34.55%)

portal,terminase,head,integrase,lysis,tail,protease,holin,capsid,transposase

attL 2159876:2159903|attR 2209261:2209288

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024181814.1\|2140581_2141928_+\|transposase	IS4-like element IS4 family transposase	NA	NA	NA	NA
WP_000301651.1\|2141982_2144658_-	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_022645592.1\|2145134_2145782_+	NAAT family transporter YchE	NA	NA	NA	NA
WP_001211525.1\|2145939_2146236_-	hypothetical protein	NA	NA	NA	NA
WP_000182039.1\|2146519_2148151_+	oligopeptide ABC transporter substrate-binding protein OppA	NA	NA	NA	NA
WP_060684418.1\|2148236_2149157_+	oligopeptide ABC transporter permease OppB	NA	NA	NA	NA
WP_000979659.1\|2149171_2150080_+	oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_000110931.1\|2150091_2151105_+	murein tripeptide/oligopeptide ABC transporter ATP binding protein OppD	G9BWD6	Planktothrix_phage	2.0e-14	31.7
WP_000994905.1\|2151101_2152106_+	murein tripeptide/oligopeptide ABC transporter ATP binding protein OppF	G3M9Y6	Bacillus_virus	2.3e-15	30.7
WP_000366959.1\|2152158_2152488_-	YciU family protein	NA	NA	NA	NA
WP_000214516.1\|2152522_2153983_-	cardiolipin synthase	NA	NA	NA	NA
WP_001309467.1\|2154125_2154299_+	YciY family protein	NA	NA	NA	NA
WP_000020078.1\|2154353_2155607_-	voltage-gated potassium channel protein	NA	NA	NA	NA
WP_000967595.1\|2155907_2156204_-	YciI family protein	NA	NA	NA	NA
WP_001357407.1\|2156427_2157144_+	TonB system transport protein TonB	NA	NA	NA	NA
WP_000108160.1\|2157183_2157582_-	acyl-CoA thioester hydrolase YciA	NA	NA	NA	NA
WP_000808667.1\|2157686_2158226_-	septation protein A	NA	NA	NA	NA
WP_000028546.1\|2158255_2158999_-	UPF0259 family protein	NA	NA	NA	NA
WP_000737224.1\|2159355_2159994_+	outer membrane protein OmpW	NA	NA	NA	NA
2159876:2159903	attL	NA	NA	NA	NA
WP_000113696.1\|2160039_2161170_-\|integrase	phage integrase Arm DNA-binding domain-containing protein	O21940	Phage_21	2.0e-103	51.7
WP_000113189.1\|2161147_2161396_-	excisionase	NA	NA	NA	NA
WP_023909115.1\|2161460_2163932_-	exonuclease	A0A192Y6E0	Salmonella_phage	2.3e-56	57.1
WP_001090200.1\|2164024_2164216_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449192.1\|2164212_2164401_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_016237926.1\|2164933_2165308_-	hypothetical protein	NA	NA	NA	NA
WP_001725971.1\|2165319_2165472_-	DUF1391 family protein	M4QQ57	Salicola_phage	1.1e-06	51.1
WP_000948454.1\|2165790_2166267_-	hypothetical protein	A0A2D1GNH0	Pseudomonas_phage	5.7e-12	53.4
WP_000711018.1\|2166391_2166715_+	transcriptional regulator	A0A0R6PH31	Moraxella_phage	6.2e-10	44.9
WP_000693906.1\|2166698_2167124_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000095673.1\|2167146_2168109_+	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	1.6e-69	51.2
WP_001468623.1\|2168149_2168572_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	3.3e-64	91.4
WP_000403785.1\|2168629_2168986_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	1.8e-58	99.2
WP_001224662.1\|2169079_2169262_+	hypothetical protein	A0A2R2Z308	Escherichia_phage	1.4e-27	100.0
WP_000753060.1\|2169254_2169431_+	hypothetical protein	A0A2R2X2A8	Escherichia_phage	6.7e-27	94.8
WP_089541817.1\|2169706_2170935_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.7e-170	95.7
WP_000967408.1\|2171632_2171845_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.1e-26	94.3
WP_032151993.1\|2172011_2172290_+	hypothetical protein	I6PCV7	Cronobacter_phage	7.4e-12	48.4
WP_023909113.1\|2172291_2173341_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	2.7e-107	54.0
WP_000904174.1\|2173353_2173713_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	3.9e-37	64.9
WP_023909112.1\|2173709_2174399_+	antiterminator	I6PDF8	Cronobacter_phage	1.8e-54	46.4
WP_000917767.1\|2174612_2174810_+	hypothetical protein	Q9MC00	Enterobacteria_phage	2.1e-29	100.0
WP_000935536.1\|2174960_2176010_+	site-specific DNA-methyltransferase	A0A0N7KZF8	Stx2-converting_phage	8.8e-199	95.7
WP_001438304.1\|2176811_2176943_+	DUF3927 family protein	H6WZJ7	Escherichia_phage	1.1e-05	96.4
WP_000871291.1\|2177223_2177559_-	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	5.2e-44	74.8
WP_023909002.1\|2177819_2179673_+	SASA family carbohydrate esterase	Q08JA2	Stx2-converting_phage	0.0e+00	89.2
WP_000284510.1\|2179822_2180038_+\|holin	class II holin family protein	G9L6J5	Escherichia_phage	9.0e-34	100.0
WP_023909003.1\|2180042_2180357_+	DUF1327 domain-containing protein	K7PGU6	Enterobacteria_phage	3.1e-51	98.1
WP_023909004.1\|2180412_2180946_+	lysozyme	K7PLY1	Enterobacteria_phage	2.5e-101	98.3
WP_024946561.1\|2180942_2181401_+\|lysis	lysis protein	K7PJW6	Enterobacteria_phage	7.5e-70	92.8
WP_000654790.1\|2181817_2182438_+	sce7726 family protein	A0A0U2RXY7	Escherichia_phage	5.1e-53	53.7
WP_023909270.1\|2182379_2183447_-	beta family protein	NA	NA	NA	NA
WP_000867575.1\|2183856_2184405_+\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	1.0e-57	84.2
WP_000622379.1\|2184376_2186305_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	9.7e-260	66.7
WP_000259002.1\|2186288_2186495_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_000831818.1\|2186491_2188084_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	4.9e-185	61.3
WP_000256835.1\|2189616_2189964_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.9e-21	55.9
WP_000522601.1\|2190021_2191050_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.1e-113	62.2
WP_000201501.1\|2191101_2191485_+	DNA-packaging protein FI	NA	NA	NA	NA
WP_001204553.1\|2191477_2191831_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	2.5e-41	69.2
WP_001575631.1\|2191845_2192421_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.1e-49	57.8
WP_000683079.1\|2192417_2192813_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	1.5e-58	82.4
WP_000235110.1\|2192820_2193573_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.2e-133	98.4
WP_000479095.1\|2193586_2194018_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	6.2e-42	68.8
WP_000533402.1\|2194044_2194458_+\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_023909007.1\|2194438_2197012_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	83.3
WP_000847298.1\|2197008_2197338_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_001335877.1\|2197337_2198036_+\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	1.7e-129	96.6
WP_000194723.1\|2198046_2198790_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	5.0e-148	98.0
WP_122997661.1\|2198735_2199368_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	1.5e-100	94.3
WP_023909008.1\|2199711_2203185_+	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	89.8
WP_001228314.1\|2203252_2203852_+	Ail/Lom family protein	Q9EV15	Enterobacteria_phage	9.1e-108	97.0
WP_023909009.1\|2204003_2207030_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A0K2FIZ6	Escherichia_phage	1.4e-55	54.6
WP_000885578.1\|2207029_2207614_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	5.0e-103	94.8
WP_000240999.1\|2207668_2208337_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_060684419.1\|2208393_2208663_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	9.3e-20	79.4
WP_000251936.1\|2208777_2208948_+	hypothetical protein	A0A0U2RK60	Escherichia_phage	9.4e-10	62.5
WP_001056491.1\|2209989_2210490_-	ferritin-like domain-containing protein	NA	NA	NA	NA
2209261:2209288	attR	NA	NA	NA	NA
WP_000807651.1\|2210575_2210755_-	general stress protein	NA	NA	NA	NA
WP_022645611.1\|2211145_2211952_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_022645612.1\|2211951_2213145_-	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_001195273.1\|2213156_2214515_-	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	3.9e-37	41.2
WP_000763524.1\|2214518_2216114_-	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	1.7e-52	38.5
WP_022645613.1\|2216113_2217676_-	anthranilate synthase component I	NA	NA	NA	NA
WP_001700591.1\|2217767_2217812_-	trp operon leader peptide	NA	NA	NA	NA
WP_001285663.1\|2217949_2218831_+	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001295575.1\|2218827_2219448_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_022645614.1\|2219475_2221365_+	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_001291217.1\|2221575_2222451_+	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_022645615.1\|2222620_2223643_+	hypothetical protein	NA	NA	NA	NA
WP_001000715.1\|2223652_2223961_+	hypothetical protein	NA	NA	NA	NA
WP_001278893.1\|2224017_2224608_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_000559277.1\|2224604_2225363_-	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	23.4
WP_000422059.1\|2225582_2226632_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5

DBSCAN-SWA_7

2992078 : 2999601

Enterobacteria_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033870520.1\|2992078_2992621_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.7e-44	57.9
WP_033870519.1\|2992625_2993504_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	3.0e-107	64.5
WP_044863830.1\|2993561_2994461_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	3.3e-29	35.2
WP_033870517.1\|2994460_2995546_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.3e-100	53.9
WP_060684449.1\|2995917_2996811_-	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.1e-45	41.7
WP_060684450.1\|2997053_2998049_-	N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans, octacis-undecaprenol 4-epimerase	A0A1V0QG29	Shearwaterpox_virus	3.3e-09	26.3
WP_001683004.1\|2998206_2999601_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	4.9e-19	31.9

DBSCAN-SWA_8

3049487 : 3078125

uncultured_Caudovirales_phage(58.33%)

portal,terminase,head,tRNA,tail,protease,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000476012.1\|3049487_3050849_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	2.5e-217	99.5
WP_001303579.1\|3051178_3051496_-	hypothetical protein	NA	NA	NA	NA
WP_022645854.1\|3051910_3052810_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	1.7e-12	29.0
WP_000178552.1\|3052891_3053671_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_022645855.1\|3053770_3054811_-	galactitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_022645856.1\|3054859_3056215_-	galactitol permease IIC component	NA	NA	NA	NA
WP_000823289.1\|3056218_3056503_-	PTS galactitol transporter subunit IIB	NA	NA	NA	NA
WP_000182901.1\|3056533_3056986_-	PTS galactitol transporter subunit IIA	NA	NA	NA	NA
WP_022645857.1\|3056995_3058258_-	tagatose-bisphosphate aldolase subunit GatZ	NA	NA	NA	NA
WP_001527276.1\|3058286_3059141_-	tagatose-bisphosphate aldolase subunit GatY	NA	NA	NA	NA
WP_000129551.1\|3059367_3060420_-	class I fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_000858523.1\|3060676_3061954_+	MFS transporter	NA	NA	NA	NA
WP_022645858.1\|3061950_3062955_+	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	9.9e-14	29.4
WP_022645859.1\|3062951_3063917_+	kinase	NA	NA	NA	NA
WP_000434040.1\|3063890_3064637_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_001361580.1\|3064688_3065507_-	glycoside hydrolase family 25 protein	D0R7H8	Paenibacillus_phage	2.5e-23	38.0
WP_022645860.1\|3065571_3066372_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_001195576.1\|3066368_3067157_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_001353111.1\|3067946_3068228_-	hypothetical protein	NA	NA	NA	NA
WP_000127869.1\|3068233_3069895_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	4.9e-276	82.3
WP_001353110.1\|3069878_3070235_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	6.1e-51	83.8
WP_001251188.1\|3070354_3070540_-	hypothetical protein	NA	NA	NA	NA
WP_001145897.1\|3070523_3070964_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	9.1e-65	76.0
WP_001287546.1\|3070963_3071266_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	1.4e-27	61.1
WP_000270251.1\|3071258_3072473_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	2.2e-209	87.3
WP_000798773.1\|3072474_3073035_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	2.6e-88	84.9
WP_000733253.1\|3073089_3074259_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	1.8e-163	76.3
WP_001053662.1\|3074545_3075052_+	hypothetical protein	NA	NA	NA	NA
WP_024167808.1\|3075087_3075336_-	hypothetical protein	NA	NA	NA	NA
WP_000126652.1\|3075352_3075778_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_000125507.1\|3075774_3076020_-	hypothetical protein	NA	NA	NA	NA
WP_000710160.1\|3076307_3078125_-	DNA primase	Q7M2A8	Enterobacteria_phage	2.6e-129	50.7

DBSCAN-SWA_9

3106357 : 3114667

Enterobacteria_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022645869.1\|3106357_3108358_+	SWIM zinc finger family protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.8
WP_001296231.1\|3108482_3108944_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	3.2e-76	99.3
WP_001295430.1\|3108984_3109455_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_012311742.1\|3109501_3110221_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001334139.1\|3110217_3111903_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	9.5e-304	99.5
WP_001240398.1\|3112124_3112856_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	2.8e-111	99.0
WP_001216963.1\|3112915_3113023_+	protein YohO	NA	NA	NA	NA
WP_022645872.1\|3113740_3114667_-	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	2.2e-23	30.8

DBSCAN-SWA_10

3509030 : 3515974

Escherichia_phage(88.89%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000017552.1\|3509030_3509183_-	hypothetical protein	G9L6F3	Escherichia_phage	1.7e-18	96.0
WP_000076001.1\|3509200_3509392_+	DUF2633 family protein	G9L6F2	Escherichia_phage	7.3e-27	100.0
WP_001295476.1\|3509702_3510221_+	glycine zipper 2TM domain-containing protein	G9L6F1	Escherichia_phage	1.3e-62	100.0
WP_022645975.1\|3510236_3510776_+	DUF5384 family protein	G9L6F0	Escherichia_phage	2.9e-44	96.6
WP_032152016.1\|3510995_3511478_-	DUF2514 domain-containing protein	A0A0F6TK39	Escherichia_coli_O157_typing_phage	3.2e-71	90.0
WP_024946531.1\|3511474_3512104_-	glycoside hydrolase family 19 protein	G9L6E8	Escherichia_phage	1.8e-114	97.6
WP_060684470.1\|3512093_3512402_-\|holin	phage holin family protein	G9L6E7	Escherichia_phage	6.0e-47	94.1
WP_001275999.1\|3512388_3512793_-	membrane protein	G9L6E6	Escherichia_phage	2.7e-63	97.0
WP_024946530.1\|3513015_3513312_-	hypothetical protein	NA	NA	NA	NA
WP_001188253.1\|3515716_3515974_+	hypothetical protein	G9L6E3	Escherichia_phage	3.4e-43	100.0

DBSCAN-SWA_11

3520108 : 3554600

Escherichia_phage(50.0%)

tail,terminase,integrase

attL 3517933:3517948|attR 3555369:3555384

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3517933:3517948	attL	NA	NA	NA	NA
WP_032152018.1\|3520108_3523498_-	hypothetical protein	A0A1E1GEP2	Vibrio_phage	3.4e-183	36.8
WP_024946525.1\|3523497_3526245_-	hypothetical protein	A0A193GYI3	Enterobacter_phage	1.2e-117	43.5
WP_000332877.1\|3526244_3526820_-	hypothetical protein	A0A0F6TJ56	Escherichia_coli_O157_typing_phage	7.0e-81	95.3
WP_000228790.1\|3526819_3527284_-	hypothetical protein	G9L6D1	Escherichia_phage	1.1e-84	99.4
WP_001018550.1\|3527283_3529755_-	hypothetical protein	G9L6D0	Escherichia_phage	0.0e+00	99.3
WP_000179260.1\|3529754_3530360_-	hypothetical protein	G9L6C9	Escherichia_phage	2.8e-112	100.0
WP_000012377.1\|3530416_3530752_-	hypothetical protein	G9L6C7	Escherichia_phage	7.7e-56	100.0
WP_024946524.1\|3530762_3531200_-	hypothetical protein	A0A0F6R7N9	Escherichia_coli_O157_typing_phage	1.9e-70	94.5
WP_024946523.1\|3531251_3532238_-	hypothetical protein	G9L6C5	Escherichia_phage	2.5e-179	94.5
WP_001048075.1\|3532252_3532948_-	peptidase	G9L6C4	Escherichia_phage	6.0e-95	100.0
WP_000133160.1\|3532950_3533247_-	hypothetical protein	G9L6C3	Escherichia_phage	1.3e-46	100.0
WP_024946522.1\|3533243_3534923_-\|tail	tail protein	G9L6C2	Escherichia_phage	3.1e-302	99.1
WP_000335899.1\|3534937_3535144_-	hypothetical protein	G9L6C1	Escherichia_phage	6.0e-11	100.0
WP_060684471.1\|3535905_3536469_+	hypothetical protein	NA	NA	NA	NA
WP_024946520.1\|3536516_3537986_-	hypothetical protein	G9L6B8	Escherichia_phage	1.2e-289	97.4
WP_024946519.1\|3537982_3538657_-\|terminase	terminase small subunit	Q287B7	Escherichia_phage	3.4e-119	99.6
WP_024946517.1\|3539149_3540079_-	DUF551 domain-containing protein	Q1MVF7	Enterobacteria_phage	7.9e-66	50.6
WP_024946516.1\|3540592_3541357_-	ead/Ea22-like family protein	A0A1B0VCG7	Salmonella_phage	2.4e-68	95.6
WP_001593200.1\|3541358_3541658_-	hypothetical protein	A5VWB2	Enterobacteria_phage	1.4e-56	97.0
WP_024946515.1\|3541654_3542200_-	hypothetical protein	J9Q748	Salmonella_phage	3.2e-83	83.2
WP_024946514.1\|3542196_3542676_-	hypothetical protein	Q9MCR3	Enterobacteria_phage	1.5e-28	54.2
WP_021558026.1\|3542737_3543085_-	hypothetical protein	A0A0F6R8N5	Escherichia_coli_O157_typing_phage	5.9e-59	96.5
WP_001066741.1\|3543202_3543988_-	hypothetical protein	A0A0F6TJ71	Escherichia_coli_O157_typing_phage	3.6e-152	99.6
WP_000086414.1\|3543984_3544800_-	helix-turn-helix domain-containing protein	Q286X4	Escherichia_phage	1.7e-117	95.6
WP_000402896.1\|3544815_3545016_-	hypothetical protein	A0A0F6TJB7	Escherichia_coli_O157_typing_phage	1.0e-31	98.5
WP_001282459.1\|3545166_3545397_-	hypothetical protein	G9L6A7	Escherichia_phage	2.6e-39	100.0
WP_000836290.1\|3545551_3546136_+	helix-turn-helix transcriptional regulator	A0A0F6R8L7	Escherichia_coli_O157_typing_phage	7.0e-105	100.0
WP_001198620.1\|3546289_3546442_+	hypothetical protein	G9L6A5	Escherichia_phage	5.4e-25	100.0
WP_001102254.1\|3546444_3546744_+	hypothetical protein	A0A0F6R7M4	Escherichia_coli_O157_typing_phage	1.4e-45	98.0
WP_000802268.1\|3546740_3547562_+	PD-(D/E)XK nuclease-like domain-containing protein	A0A2R9YJH7	Escherichia_phage	1.2e-163	100.0
WP_000063834.1\|3547558_3548500_+	recombinase RecT	A0A2R9YJJ1	Escherichia_phage	4.5e-178	100.0
WP_000675390.1\|3548549_3548798_+	AlpA family phage regulatory protein	A0A0F6TJ45	Escherichia_coli_O157_typing_phage	3.6e-42	100.0
WP_001335975.1\|3548955_3549207_+	PerC family transcriptional regulator	G9L6A0	Escherichia_phage	3.1e-41	100.0
WP_000163456.1\|3549199_3549850_+	adenine methylase	A0A2R9YJG0	Escherichia_phage	5.0e-128	100.0
WP_001077944.1\|3549846_3550041_+	DUF1382 family protein	A0A0F6R7M7	Escherichia_coli_O157_typing_phage	9.7e-27	98.4
WP_024946512.1\|3550044_3551295_-\|integrase	site-specific integrase	A0A0F6TJM5	Escherichia_coli_O157_typing_phage	3.0e-238	99.3
WP_000138270.1\|3551487_3553065_-	glutamine-hydrolyzing GMP synthase	NA	NA	NA	NA
WP_001299507.1\|3553133_3554600_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.3e-88	39.1
3555369:3555384	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP008715

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP008697

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection