CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012018	Staphylococcus aureus subsp. aureus strain Gv88 chromosome, complete genome	11 crisprs	WYL,cas3,DEDDh,DinG,csa3	7	2	14	0
NZ_CP012017	Staphylococcus aureus subsp. aureus strain Gv88 plasmid pGv88, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012018_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_1

443775-443875

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012018_1

>merge|NZ_CP012018|1|443775-443875|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>NZ_CP012018|1|1|443775-443875|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_000746687.1\|437021_437648_-\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_CP012018.1\|WP_000424966.1\|450065_451607_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP012018.1\|WP_001789518.1\|442999_443101_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000793009.1\|447268_448537_+\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP012018.1\|WP_001055897.1\|434496_434760_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP012018.1\|WP_000211676.1\|435349_435559_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000394698.1\|444965_445628_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000868248.1\|436383_436767_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000763768.1\|445770_446178_-\|general-stress-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP012018.1\|WP_001289311.1\|440690_441446_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NZ_CP012018.1\|WP_000633907.1\|452894_453095_-\|DUF3173-domain-containing-protein	unknown	unknown	gnl\|CDD\|371495
NZ_CP012018.1\|WP_000264071.1\|448574_450041_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_CP012018.1\|WP_000991007.1\|441526_442915_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP012018.1\|WP_000845143.1\|453592_453823_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378900
NZ_CP012018.1\|WP_000237797.1\|451674_452868_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP012018.1\|WP_000421410.1\|446690_447269_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_CP012018.1\|WP_000158374.1\|435736_436318_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP012018.1\|WP_000956132.1\|443891_444848_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NZ_CP012018.1\|WP_000466748.1\|435059_435311_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP012018.1\|WP_000052781.1\|439629_440199_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000746687.1\|437021_437648_-\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
NZ_CP012018.1\|WP_000424966.1\|450065_451607_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP012018.1\|WP_000793009.1\|447268_448537_+\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
NZ_CP012018.1\|WP_001055897.1\|434496_434760_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.0037414
NZ_CP012018.1\|WP_000763768.1\|445770_446178_-\|general-stress-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
NZ_CP012018.1\|WP_000264071.1\|448574_450041_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_CP012018.1\|WP_001289311.1\|440690_441446_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
NZ_CP012018.1\|WP_000633907.1\|452894_453095_-\|DUF3173-domain-containing-protein	gnl\|CDD\|371495	pfam11372, DUF3173, Domain of unknown function (DUF3173). This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualisation confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).	2.02242e-22
NZ_CP012018.1\|WP_000991007.1\|441526_442915_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP012018.1\|WP_000845143.1\|453592_453823_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378900	pfam12645, HTH_16, Helix-turn-helix domain. This domain appears to be a helix-turn-helix domain suggesting that this might be a transcriptional regulatory protein. Some members of this family are annotated as conjugative transposon domains.	2.04673e-25
NZ_CP012018.1\|WP_000237797.1\|451674_452868_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.36769e-47
NZ_CP012018.1\|WP_000421410.1\|446690_447269_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
NZ_CP012018.1\|WP_000158374.1\|435736_436318_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.78414e-49
NZ_CP012018.1\|WP_000956132.1\|443891_444848_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
NZ_CP012018.1\|WP_000466748.1\|435059_435311_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
NZ_CP012018.1\|WP_000052781.1\|439629_440199_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124

>NZ_CP012018.1|WP_001789518.1|442999_443101_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNSVVIGGKGK
>NZ_CP012018.1|WP_000991007.1|441526_442915_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>NZ_CP012018.1|WP_001289311.1|440690_441446_+|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NZ_CP012018.1|WP_000052781.1|439629_440199_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NZ_CP012018.1|WP_000746687.1|437021_437648_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NZ_CP012018.1|WP_000868248.1|436383_436767_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>NZ_CP012018.1|WP_000158374.1|435736_436318_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>NZ_CP012018.1|WP_000211676.1|435349_435559_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFNPILSTFSNIIIHIDHFHANKKDDN
>NZ_CP012018.1|WP_000466748.1|435059_435311_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>NZ_CP012018.1|WP_001055897.1|434496_434760_-|helix-turn-helix-transcriptional-regulator
MNMHILYNLRTKHNLEIDELAQQLNEKYGTKYEAHQIWEWENHHHEPKFKDAMHLADFFDAPYEMFLESKVKEYQKHLEEVDIRMDK
>NZ_CP012018.1|WP_000956132.1|443891_444848_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NZ_CP012018.1|WP_000394698.1|444965_445628_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NZ_CP012018.1|WP_000763768.1|445770_446178_-|general-stress-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>NZ_CP012018.1|WP_000421410.1|446690_447269_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NZ_CP012018.1|WP_000793009.1|447268_448537_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NZ_CP012018.1|WP_000264071.1|448574_450041_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NZ_CP012018.1|WP_000424966.1|450065_451607_+|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NZ_CP012018.1|WP_000237797.1|451674_452868_-|site-specific-integrase
MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEAREEYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFDKMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGNVKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDIDFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQTDFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDRLGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKEMKKVQ
>NZ_CP012018.1|WP_000633907.1|452894_453095_-|DUF3173-domain-containing-protein
MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLDRVPREAVEEILGIRFSNENRSE
>NZ_CP012018.1|WP_000845143.1|453592_453823_-|helix-turn-helix-domain-containing-protein
MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMTDEYGNSHMVIDETLRGRMETKLISKILSFEIK

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP012018_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_2

709405-709497

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012018_2

>merge|NZ_CP012018|2|709405-709497|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>NZ_CP012018|2|2|709405-709497|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_000365354.1\|711605_712325_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP012018.1\|WP_078102485.1\|710600_711551_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP012018.1\|WP_041205331.1\|705888_705996_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000169042.1\|718283_718508_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP012018.1\|WP_001045421.1\|714797_715586_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP012018.1\|WP_000901764.1\|708551_709187_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP012018.1\|WP_000180230.1\|702460_703756_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP012018.1\|WP_001222133.1\|713912_714629_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000749059.1\|709565_710453_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_CP012018.1\|WP_000362972.1\|712308_713109_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP012018.1\|WP_001553862.1\|717159_718089_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_CP012018.1\|WP_000359086.1\|706088_706505_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP012018.1\|WP_000477504.1\|701944_702421_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP012018.1\|WP_001018677.1\|715836_716211_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP012018.1\|WP_000808902.1\|700090_701029_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP012018.1\|WP_001788287.1\|703783_704305_+\|YwhD-family-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP012018.1\|WP_000633782.1\|701239_701776_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP012018.1\|WP_000735558.1\|713244_713751_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_001021145.1\|706501_708163_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP012018.1\|WP_001200748.1\|704803_705814_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000365354.1\|711605_712325_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_CP012018.1\|WP_000169042.1\|718283_718508_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
NZ_CP012018.1\|WP_001045421.1\|714797_715586_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
NZ_CP012018.1\|WP_000901764.1\|708551_709187_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
NZ_CP012018.1\|WP_000180230.1\|702460_703756_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NZ_CP012018.1\|WP_000749059.1\|709565_710453_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.54601e-73
NZ_CP012018.1\|WP_000362972.1\|712308_713109_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.35732e-24
NZ_CP012018.1\|WP_001553862.1\|717159_718089_-\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	7.93315e-37
NZ_CP012018.1\|WP_078102485.1\|710600_711551_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	2.92743e-48
NZ_CP012018.1\|WP_000477504.1\|701944_702421_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_CP012018.1\|WP_001018677.1\|715836_716211_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NZ_CP012018.1\|WP_000359086.1\|706088_706505_+\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58
NZ_CP012018.1\|WP_000808902.1\|700090_701029_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NZ_CP012018.1\|WP_001788287.1\|703783_704305_+\|YwhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP012018.1\|WP_000633782.1\|701239_701776_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
NZ_CP012018.1\|WP_001021145.1\|706501_708163_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP012018.1\|WP_001200748.1\|704803_705814_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0

>NZ_CP012018.1|WP_000901764.1|708551_709187_+|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP012018.1|WP_001021145.1|706501_708163_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP012018.1|WP_000359086.1|706088_706505_+|DUF1934-domain-containing-protein
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP012018.1|WP_041205331.1|705888_705996_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMVYIYEALIKYGIVN
>NZ_CP012018.1|WP_001200748.1|704803_705814_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP012018.1|WP_001788287.1|703783_704305_+|YwhD-family-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP012018.1|WP_000180230.1|702460_703756_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP012018.1|WP_000477504.1|701944_702421_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_CP012018.1|WP_000633782.1|701239_701776_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_CP012018.1|WP_000808902.1|700090_701029_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>NZ_CP012018.1|WP_000749059.1|709565_710453_+|ABC-transporter-substrate-binding-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP012018.1|WP_078102485.1|710600_711551_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTNIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP012018.1|WP_000365354.1|711605_712325_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_CP012018.1|WP_000362972.1|712308_713109_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMSGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_CP012018.1|WP_000735558.1|713244_713751_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP012018.1|WP_001222133.1|713912_714629_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_CP012018.1|WP_001045421.1|714797_715586_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>NZ_CP012018.1|WP_001018677.1|715836_716211_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP012018.1|WP_001553862.1|717159_718089_-|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NZ_CP012018.1|WP_000169042.1|718283_718508_-|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK

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Crispr_ID: NZ_CP012018_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_3

829649-829731

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012018_3

>merge|NZ_CP012018|3|829649-829731|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>NZ_CP012018|3|3|829649-829731|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_000525109.1\|820926_822810_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP012018.1\|WP_000180991.1\|825794_827309_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_CP012018.1\|WP_000589260.1\|824824_825802_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_CP012018.1\|WP_000876318.1\|839662_840634_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NZ_CP012018.1\|WP_000197271.1\|828957_829500_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NZ_CP012018.1\|WP_000930014.1\|833212_833713_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851
NZ_CP012018.1\|WP_001068503.1\|833732_834599_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_CP012018.1\|WP_000855505.1\|835760_837866_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NZ_CP012018.1\|WP_000983677.1\|822821_824603_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NZ_CP012018.1\|WP_001790641.1\|831187_831289_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000499195.1\|839468_839624_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_001790169.1\|816249_816456_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000663030.1\|827548_828607_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NZ_CP012018.1\|WP_000692521.1\|835399_835798_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NZ_CP012018.1\|WP_000098285.1\|818715_820656_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NZ_CP012018.1\|WP_000193751.1\|831366_832872_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_CP012018.1\|WP_000562498.1\|837983_838955_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_CP012018.1\|WP_000708692.1\|816543_817254_+\|allophanate-hydrolase-subunit-1	unknown	unknown	gnl\|CDD\|224960
NZ_CP012018.1\|WP_000022323.1\|817237_818242_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NZ_CP012018.1\|WP_000429014.1\|830179_831097_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000525109.1\|820926_822810_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_CP012018.1\|WP_000180991.1\|825794_827309_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
NZ_CP012018.1\|WP_000589260.1\|824824_825802_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.80291e-155
NZ_CP012018.1\|WP_000876318.1\|839662_840634_+\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
NZ_CP012018.1\|WP_000197271.1\|828957_829500_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	1.15481e-107
NZ_CP012018.1\|WP_000930014.1\|833212_833713_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
NZ_CP012018.1\|WP_001068503.1\|833732_834599_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	2.88244e-10
NZ_CP012018.1\|WP_000855505.1\|835760_837866_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_CP012018.1\|WP_000983677.1\|822821_824603_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP012018.1\|WP_000708692.1\|816543_817254_+\|allophanate-hydrolase-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.29969e-94
NZ_CP012018.1\|WP_000663030.1\|827548_828607_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NZ_CP012018.1\|WP_000692521.1\|835399_835798_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NZ_CP012018.1\|WP_000098285.1\|818715_820656_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NZ_CP012018.1\|WP_000193751.1\|831366_832872_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
NZ_CP012018.1\|WP_000562498.1\|837983_838955_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NZ_CP012018.1\|WP_000022323.1\|817237_818242_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
NZ_CP012018.1\|WP_000429014.1\|830179_831097_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	3.10512e-78

>NZ_CP012018.1|WP_000197271.1|828957_829500_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPYAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NZ_CP012018.1|WP_000663030.1|827548_828607_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NZ_CP012018.1|WP_000180991.1|825794_827309_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NZ_CP012018.1|WP_000589260.1|824824_825802_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQLLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NZ_CP012018.1|WP_000983677.1|822821_824603_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NZ_CP012018.1|WP_000525109.1|820926_822810_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMMDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREENEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NZ_CP012018.1|WP_000098285.1|818715_820656_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NZ_CP012018.1|WP_000022323.1|817237_818242_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NZ_CP012018.1|WP_000708692.1|816543_817254_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDLESLLKHYKIKLETFIELHSKAQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>NZ_CP012018.1|WP_001790169.1|816249_816456_+|hypothetical-protein
MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIATITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NZ_CP012018.1|WP_000429014.1|830179_831097_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMTHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NZ_CP012018.1|WP_001790641.1|831187_831289_+|hypothetical-protein
MVINEIDFYRVGRENIVIAVYNEHIKFLFILIS
>NZ_CP012018.1|WP_000193751.1|831366_832872_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NZ_CP012018.1|WP_000930014.1|833212_833713_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NZ_CP012018.1|WP_001068503.1|833732_834599_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFYIYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NZ_CP012018.1|WP_000692521.1|835399_835798_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NZ_CP012018.1|WP_000855505.1|835760_837866_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NZ_CP012018.1|WP_000562498.1|837983_838955_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NZ_CP012018.1|WP_000499195.1|839468_839624_+|hypothetical-protein
MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNATINEKYYQ
>NZ_CP012018.1|WP_000876318.1|839662_840634_+|ABC-transporter-permease
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

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Crispr_ID: NZ_CP012018_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_4

870701-870781

Unclear

Consensus_repeat	Method
TTCTTTATGTTGGGGCCCCGCCAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012018_4

>merge|NZ_CP012018|4|870701-870781|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACTTGCATTGTTTGTAGAATTTCTTTTCGAAATTCTTTATGTTGGGGCCCCGCCAACT

>NZ_CP012018|4|4|870701-870781|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACT	TGCATTGTTTGTAGAATTTCTTTTCGAAA
TTCTTTATGTTGGGGCCCCGCCAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_000749380.1\|863406_864246_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP012018.1\|WP_000638419.1\|865066_865303_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP012018.1\|WP_000006551.1\|878515_879460_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP012018.1\|WP_001224793.1\|872802_873288_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP012018.1\|WP_001049165.1\|880032_880620_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP012018.1\|WP_001248939.1\|877410_878406_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP012018.1\|WP_001790093.1\|863151_863259_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000134963.1\|874801_875737_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP012018.1\|WP_000057549.1\|873295_874735_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP012018.1\|WP_000617735.1\|858055_858628_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_CP012018.1\|WP_001790092.1\|861614_861719_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000506531.1\|859041_861573_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP012018.1\|WP_000816295.1\|880862_881765_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP012018.1\|WP_000513308.1\|871955_872795_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP012018.1\|WP_010956549.1\|861887_862998_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP012018.1\|WP_000369722.1\|876502_877414_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP012018.1\|WP_041205335.1\|865571_867557_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP012018.1\|WP_000662681.1\|867564_870411_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP012018.1\|WP_000538141.1\|864419_865070_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP012018.1\|WP_000958224.1\|871017_871950_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000749380.1\|863406_864246_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
NZ_CP012018.1\|WP_000638419.1\|865066_865303_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP012018.1\|WP_000006551.1\|878515_879460_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP012018.1\|WP_041205335.1\|865571_867557_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP012018.1\|WP_001248939.1\|877410_878406_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP012018.1\|WP_000134963.1\|874801_875737_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP012018.1\|WP_000057549.1\|873295_874735_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.31987e-06
NZ_CP012018.1\|WP_000617735.1\|858055_858628_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NZ_CP012018.1\|WP_000513308.1\|871955_872795_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
NZ_CP012018.1\|WP_000506531.1\|859041_861573_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP012018.1\|WP_000816295.1\|880862_881765_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
NZ_CP012018.1\|WP_001049165.1\|880032_880620_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP012018.1\|WP_010956549.1\|861887_862998_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP012018.1\|WP_000369722.1\|876502_877414_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP012018.1\|WP_001224793.1\|872802_873288_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP012018.1\|WP_000662681.1\|867564_870411_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP012018.1\|WP_000538141.1\|864419_865070_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP012018.1\|WP_000958224.1\|871017_871950_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170

>NZ_CP012018.1|WP_000662681.1|867564_870411_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP012018.1|WP_041205335.1|865571_867557_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAVRNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP012018.1|WP_000638419.1|865066_865303_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP012018.1|WP_000538141.1|864419_865070_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP012018.1|WP_000749380.1|863406_864246_+|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP012018.1|WP_001790093.1|863151_863259_+|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIIENVLNYMV
>NZ_CP012018.1|WP_010956549.1|861887_862998_+|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NZ_CP012018.1|WP_001790092.1|861614_861719_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NZ_CP012018.1|WP_000506531.1|859041_861573_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NZ_CP012018.1|WP_000617735.1|858055_858628_+|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NZ_CP012018.1|WP_000958224.1|871017_871950_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP012018.1|WP_000513308.1|871955_872795_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP012018.1|WP_001224793.1|872802_873288_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP012018.1|WP_000057549.1|873295_874735_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLSDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP012018.1|WP_000134963.1|874801_875737_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP012018.1|WP_000369722.1|876502_877414_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP012018.1|WP_001248939.1|877410_878406_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP012018.1|WP_000006551.1|878515_879460_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP012018.1|WP_001049165.1|880032_880620_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP012018.1|WP_000816295.1|880862_881765_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

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Crispr_ID: NZ_CP012018_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_5

920527-920608

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012018_5

>merge|NZ_CP012018|5|920527-920608|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP012018|5|5|920527-920608|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_001186979.1\|927434_928007_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP012018.1\|WP_000932216.1\|919544_920423_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP012018.1\|WP_000255561.1\|914284_914902_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP012018.1\|WP_000560872.1\|928178_928400_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NZ_CP012018.1\|WP_000422909.1\|917318_917858_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP012018.1\|WP_001190695.1\|918007_918328_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP012018.1\|WP_000589549.1\|918471_918828_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP012018.1\|WP_001018962.1\|921164_921551_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP012018.1\|WP_001065801.1\|921543_921840_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP012018.1\|WP_000571218.1\|922089_923115_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP012018.1\|WP_000124597.1\|928400_928673_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379251
NZ_CP012018.1\|WP_000974460.1\|915949_916372_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP012018.1\|WP_000290485.1\|918985_919366_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP012018.1\|WP_001637664.1\|926019_927408_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_CP012018.1\|WP_000569884.1\|915056_915551_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP012018.1\|WP_000520233.1\|923107_923803_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP012018.1\|WP_020444648.1\|924785_926006_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP012018.1\|WP_000732326.1\|923820_924642_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP012018.1\|WP_000150017.1\|916519_917236_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP012018.1\|WP_001140686.1\|913630_914212_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_001186979.1\|927434_928007_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.00645e-06
NZ_CP012018.1\|WP_000932216.1\|919544_920423_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.16579e-75
NZ_CP012018.1\|WP_000255561.1\|914284_914902_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	9.12336e-62
NZ_CP012018.1\|WP_000560872.1\|928178_928400_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	2.70121e-07
NZ_CP012018.1\|WP_000422909.1\|917318_917858_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.47647e-49
NZ_CP012018.1\|WP_001190695.1\|918007_918328_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_CP012018.1\|WP_000589549.1\|918471_918828_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP012018.1\|WP_001018962.1\|921164_921551_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP012018.1\|WP_001065801.1\|921543_921840_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP012018.1\|WP_000571218.1\|922089_923115_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_CP012018.1\|WP_000124597.1\|928400_928673_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379251	pfam13545, HTH_Crp_2, Crp-like helix-turn-helix domain. This family represents a crp-like helix-turn-helix domain that is likely to bind DNA.	0.00479643
NZ_CP012018.1\|WP_000974460.1\|915949_916372_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP012018.1\|WP_000290485.1\|918985_919366_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
NZ_CP012018.1\|WP_001637664.1\|926019_927408_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	1.34231e-08
NZ_CP012018.1\|WP_000569884.1\|915056_915551_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP012018.1\|WP_000520233.1\|923107_923803_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_CP012018.1\|WP_020444648.1\|924785_926006_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.18129e-37
NZ_CP012018.1\|WP_000732326.1\|923820_924642_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NZ_CP012018.1\|WP_000150017.1\|916519_917236_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.26721e-148
NZ_CP012018.1\|WP_001140686.1\|913630_914212_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.48911e-47

>NZ_CP012018.1|WP_000932216.1|919544_920423_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP012018.1|WP_000290485.1|918985_919366_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>NZ_CP012018.1|WP_000589549.1|918471_918828_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP012018.1|WP_001190695.1|918007_918328_-|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP012018.1|WP_000422909.1|917318_917858_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEGDMPKAPRKNRNLITLY
>NZ_CP012018.1|WP_000150017.1|916519_917236_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>NZ_CP012018.1|WP_000974460.1|915949_916372_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP012018.1|WP_000569884.1|915056_915551_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP012018.1|WP_000255561.1|914284_914902_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>NZ_CP012018.1|WP_001140686.1|913630_914212_+|histidine-phosphatase-family-protein
MAKTLYIMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGIFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>NZ_CP012018.1|WP_001018962.1|921164_921551_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP012018.1|WP_001065801.1|921543_921840_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP012018.1|WP_000571218.1|922089_923115_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP012018.1|WP_000520233.1|923107_923803_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP012018.1|WP_000732326.1|923820_924642_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP012018.1|WP_020444648.1|924785_926006_-|site-specific-integrase
MWHEKFTNKHGETKYRYYEKYKDPLTNKWRRVSVVLNKNGKQSQKEAQRRLNERIEAKLNDNTPTTLKSLTFHVACDEWFQNYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDSKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINMKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQNEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
>NZ_CP012018.1|WP_001637664.1|926019_927408_-|SAP-domain-containing-protein
MKKIFYCFLLIFSILMIFGGINEVTQNKLTFIDIFMFAIFISLIVFSIVKLFKHNHLDYKSNKSNTNHKNISNSKTTQFNTVQSNDHIRKNNITHDIETNNTKKVKQVKSITNNKTNTLNKDQVKLNENVQENNQDLVIDVKDDNNNNYHYDLNANDILILHLNKNREVGKEVKNHFYLLENQINVDEILNKLINLDYLDIKSNFDVSLFYLKVPELKEILREYKLKLSGNKPELIERIKTNIDENAIKLPQVYVPTSKGNKIIGETEYILHFYNSPIISLGSAHKMAKEVLNIDDKIEYIYFYLLQQNQKSNNSDHRTANIINSLVLYYKKTNKDKDVIRKYTNYATYLSVTQGIHSAAFLYSSEENIIDRLFIYFNYHLEYYENMLFIDNVSRRLFKNLFYEDIKSFEDTDKNFCDEICELLFAQIYNNRNITLNNLPTINYVLEKIKKENEIRMTKYDF
>NZ_CP012018.1|WP_001186979.1|927434_928007_-|helix-turn-helix-transcriptional-regulator
MQQNSLEDFSNILKNFRKEEDLTLDTLSKYLGVSDVYVSKLENGKRFPSKNILFWYVLFMDQSQMHDDIEKLLTIFSENKKIRYEQLRTEYDEFVKKFREKQKKHSSKIQRKEIKLTMNEFNQYQIEEIDEPYFDLKWLLNQSEYKLFYSGIDNKNSLGFNEVLSESDKKMLSEIVNSVIQRIYNDENQK
>NZ_CP012018.1|WP_000560872.1|928178_928400_+|helix-turn-helix-transcriptional-regulator
MIAKVNYLKRLIAFEGLSLKDFASEIEVNSNFLNSIVNGKRTTSPKTANKIAKRLNVDIKDIFIFIEEKEEVK
>NZ_CP012018.1|WP_000124597.1|928400_928673_+|helix-turn-helix-domain-containing-protein
MARTKLKDIPTKENTISEPKQVVVKPLFAKPNALASIFGISYSSTNRILKEWEKDPKGVDDLYYSLSSTMTVISIPRFEEYMKKRHKKWM

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP012018_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_6

1117045-1117132

Orphan

Consensus_repeat	Method
CCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012018_6

>merge|NZ_CP012018|6|1117045-1117132|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGGAAGGAGAGGGATACATGCGCCGAGCACATGCATAAAATCCCCTAACAACTAAAAGTTGTAAGG

>NZ_CP012018|6|6|1117045-1117132|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGG	AAGGAGAGGGATACATGCGCCGAGCACATGCATAAAAT
CCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_000238664.1\|1110175_1110742_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
NZ_CP012018.1\|WP_059283852.1\|1121338_1123057_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP012018.1\|WP_020444657.1\|1114567_1115968_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP012018.1\|WP_000032727.1\|1105499_1107689_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_CP012018.1\|WP_000483713.1\|1107667_1109152_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NZ_CP012018.1\|WP_000514290.1\|1126234_1126897_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP012018.1\|WP_000505965.1\|1120373_1120916_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
NZ_CP012018.1\|WP_001289614.1\|1123293_1123527_-\|glutaredoxin-like-protein-NrdH	unknown	unknown	gnl\|CDD\|239274
NZ_CP012018.1\|WP_001101908.1\|1112256_1113504_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
NZ_CP012018.1\|WP_000638456.1\|1125082_1126102_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NZ_CP012018.1\|WP_000437472.1\|1121069_1121336_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NZ_CP012018.1\|WP_000030812.1\|1109144_1110173_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP012018.1\|WP_000666799.1\|1104835_1105507_+\|phosphoribosylformylglycinamidine-synthase-I	unknown	unknown	gnl\|CDD\|235140
NZ_CP012018.1\|WP_020444658.1\|1119147_1120320_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_CP012018.1\|WP_000273253.1\|1113768_1114575_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP012018.1\|WP_000009069.1\|1117427_1118723_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000381849.1\|1123724_1125086_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP012018.1\|WP_000064214.1\|1117141_1117276_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000033477.1\|1115982_1116558_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227065
NZ_CP012018.1\|WP_000709290.1\|1110756_1112235_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000238664.1\|1110175_1110742_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	7.23817e-92
NZ_CP012018.1\|WP_059283852.1\|1121338_1123057_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP012018.1\|WP_020444657.1\|1114567_1115968_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	5.55952e-63
NZ_CP012018.1\|WP_000032727.1\|1105499_1107689_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP012018.1\|WP_000483713.1\|1107667_1109152_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NZ_CP012018.1\|WP_000514290.1\|1126234_1126897_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
NZ_CP012018.1\|WP_000437472.1\|1121069_1121336_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
NZ_CP012018.1\|WP_001289614.1\|1123293_1123527_-\|glutaredoxin-like-protein-NrdH	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	5.00495e-16
NZ_CP012018.1\|WP_001101908.1\|1112256_1113504_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP012018.1\|WP_000030812.1\|1109144_1110173_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP012018.1\|WP_000666799.1\|1104835_1105507_+\|phosphoribosylformylglycinamidine-synthase-I	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.77638e-140
NZ_CP012018.1\|WP_000033477.1\|1115982_1116558_-\|ECF-transporter-S-component	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
NZ_CP012018.1\|WP_000273253.1\|1113768_1114575_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.39205e-29
NZ_CP012018.1\|WP_000505965.1\|1120373_1120916_+\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00779365
NZ_CP012018.1\|WP_000381849.1\|1123724_1125086_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
NZ_CP012018.1\|WP_000638456.1\|1125082_1126102_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	6.42118e-76
NZ_CP012018.1\|WP_020444658.1\|1119147_1120320_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	6.37648e-144
NZ_CP012018.1\|WP_000709290.1\|1110756_1112235_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0

>NZ_CP012018.1|WP_000033477.1|1115982_1116558_-|ECF-transporter-S-component
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>NZ_CP012018.1|WP_020444657.1|1114567_1115968_-|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQLPCEDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>NZ_CP012018.1|WP_000273253.1|1113768_1114575_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITMAYYCSITLPITGIDDVRLGRVG
>NZ_CP012018.1|WP_001101908.1|1112256_1113504_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVHTEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYKKVSQIQSDHLFYRHDIANKALQLK
>NZ_CP012018.1|WP_000709290.1|1110756_1112235_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>NZ_CP012018.1|WP_000238664.1|1110175_1110742_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRKCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>NZ_CP012018.1|WP_000030812.1|1109144_1110173_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDVSRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>NZ_CP012018.1|WP_000483713.1|1107667_1109152_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>NZ_CP012018.1|WP_000032727.1|1105499_1107689_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>NZ_CP012018.1|WP_000666799.1|1104835_1105507_+|phosphoribosylformylglycinamidine-synthase-I
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>NZ_CP012018.1|WP_000064214.1|1117141_1117276_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>NZ_CP012018.1|WP_000009069.1|1117427_1118723_+|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>NZ_CP012018.1|WP_020444658.1|1119147_1120320_+|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQQINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSAIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGVLNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>NZ_CP012018.1|WP_000505965.1|1120373_1120916_+|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISNAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>NZ_CP012018.1|WP_000437472.1|1121069_1121336_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>NZ_CP012018.1|WP_059283852.1|1121338_1123057_+|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQSDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMGGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>NZ_CP012018.1|WP_001289614.1|1123293_1123527_-|glutaredoxin-like-protein-NrdH
MSEIIVYTQNDCPPCTFVKNYLNEHHIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>NZ_CP012018.1|WP_000381849.1|1123724_1125086_+|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>NZ_CP012018.1|WP_000638456.1|1125082_1126102_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFGISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>NZ_CP012018.1|WP_000514290.1|1126234_1126897_+|TrkA-family-potassium-uptake-protein
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

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Crispr_ID: NZ_CP012018_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_7

1245002-1245087

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012018_7

>merge|NZ_CP012018|7|1245002-1245087|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGG

>NZ_CP012018|7|7|1245002-1245087|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGCTGGCGG
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_000765708.1\|1244434_1244581_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_001245802.1\|1253789_1253978_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NZ_CP012018.1\|WP_001802045.1\|1244537_1244762_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_059283877.1\|1250197_1251754_+\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_CP012018.1\|WP_001239288.1\|1252593_1253541_-\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NZ_CP012018.1\|WP_000739523.1\|1246906_1247632_-\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_CP012018.1\|WP_001791789.1\|1237572_1237665_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000739563.1\|1237624_1238026_-\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NZ_CP012018.1\|WP_000584398.1\|1238697_1239204_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000398672.1\|1254889_1255024_+\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_CP012018.1\|WP_000231632.1\|1242092_1242326_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_001032814.1\|1241285_1241471_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_001074342.1\|1249093_1250026_+\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_CP012018.1\|WP_000149423.1\|1252061_1252289_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000848124.1\|1242802_1243762_-\|alpha-hemolysin	unknown	unknown	gnl\|CDD\|273388
NZ_CP012018.1\|WP_000793605.1\|1248069_1249071_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_CP012018.1\|WP_000669537.1\|1240113_1240464_+\|complement-inhibitor-SCIN-B	unknown	unknown	gnl\|CDD\|371594
NZ_CP012018.1\|WP_001063559.1\|1246086_1246812_-\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_CP012018.1\|WP_020444705.1\|1245262_1245979_-\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
NZ_CP012018.1\|WP_000791587.1\|1239462_1239960_+\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_001245802.1\|1253789_1253978_+\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
NZ_CP012018.1\|WP_001239288.1\|1252593_1253541_-\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	1.39126e-83
NZ_CP012018.1\|WP_000739523.1\|1246906_1247632_-\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
NZ_CP012018.1\|WP_000791587.1\|1239462_1239960_+\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.40265e-27
NZ_CP012018.1\|WP_000739563.1\|1237624_1238026_-\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	3.87075e-77
NZ_CP012018.1\|WP_000398672.1\|1254889_1255024_+\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
NZ_CP012018.1\|WP_059283877.1\|1250197_1251754_+\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_CP012018.1\|WP_001074342.1\|1249093_1250026_+\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_CP012018.1\|WP_000848124.1\|1242802_1243762_-\|alpha-hemolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.62736e-140
NZ_CP012018.1\|WP_000793605.1\|1248069_1249071_+\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_CP012018.1\|WP_000669537.1\|1240113_1240464_+\|complement-inhibitor-SCIN-B	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
NZ_CP012018.1\|WP_001063559.1\|1246086_1246812_-\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
NZ_CP012018.1\|WP_020444705.1\|1245262_1245979_-\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.46782e-151

>NZ_CP012018.1|WP_001802045.1|1244537_1244762_+|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_CP012018.1|WP_000765708.1|1244434_1244581_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_CP012018.1|WP_000848124.1|1242802_1243762_-|alpha-hemolysin
MKTHIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>NZ_CP012018.1|WP_000231632.1|1242092_1242326_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_CP012018.1|WP_001032814.1|1241285_1241471_-|hypothetical-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_CP012018.1|WP_000669537.1|1240113_1240464_+|complement-inhibitor-SCIN-B
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>NZ_CP012018.1|WP_000791587.1|1239462_1239960_+|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>NZ_CP012018.1|WP_000584398.1|1238697_1239204_+|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_CP012018.1|WP_000739563.1|1237624_1238026_-|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY
>NZ_CP012018.1|WP_001791789.1|1237572_1237665_-|hypothetical-protein
MLKTVKSTRLLGIKKHTELNSCTPNVRKQC
>NZ_CP012018.1|WP_020444705.1|1245262_1245979_-|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENLNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>NZ_CP012018.1|WP_001063559.1|1246086_1246812_-|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_CP012018.1|WP_000739523.1|1246906_1247632_-|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NZ_CP012018.1|WP_000793605.1|1248069_1249071_+|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEIMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_CP012018.1|WP_001074342.1|1249093_1250026_+|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NZ_CP012018.1|WP_059283877.1|1250197_1251754_+|YfcC-family-protein
MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKLGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGDIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>NZ_CP012018.1|WP_000149423.1|1252061_1252289_+|hypothetical-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NZ_CP012018.1|WP_001239288.1|1252593_1253541_-|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLKNVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>NZ_CP012018.1|WP_001245802.1|1253789_1253978_+|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>NZ_CP012018.1|WP_000398672.1|1254889_1255024_+|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF

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Crispr_ID: NZ_CP012018_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_8

2116596-2116674

Orphan

Consensus_repeat	Method
AATTTCTCTATGTTGGGGCCCCG	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP012018_8

>merge|NZ_CP012018|8|2116596-2116674|CRISPRCasFinder
AATTTCTCTATGTTGGGGCCCCGCCAACCTGCATTGCCTGTAGAATTTCTTTTTTGAAATTCTCTATGTTGGGGCCCCG

>NZ_CP012018|8|8|2116596-2116674|CRISPRCasFinder
AATTTCTCTATGTTGGGGCCCCG	CCAACCTGCATTGCCTGTAGAATTTCTTTTTTG
AAATTCTCTATGTTGGGGCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_000949467.1\|2121287_2121788_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_CP012018.1\|WP_000544969.1\|2118949_2119681_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP012018.1\|WP_000140176.1\|2122798_2123869_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP012018.1\|WP_001790679.1\|2121869_2121962_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000548781.1\|2124115_2124646_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_CP012018.1\|WP_001795438.1\|2108723_2109980_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_CP012018.1\|WP_000228666.1\|2110329_2110794_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP012018.1\|WP_001549145.1\|2118311_2118725_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000428172.1\|2110800_2111076_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000999713.1\|2116894_2117881_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP012018.1\|WP_001017131.1\|2113305_2114349_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP012018.1\|WP_000153530.1\|2112686_2113316_-\|two-component-system-response-regulator-VraR	unknown	unknown	gnl\|CDD\|225107
NZ_CP012018.1\|WP_001790257.1\|2118753_2118864_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000149064.1\|2114345_2115047_-\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NZ_CP012018.1\|WP_000613733.1\|2122176_2122731_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP012018.1\|WP_000636142.1\|2115664_2116423_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP012018.1\|WP_000037075.1\|2111353_2112571_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP012018.1\|WP_001110179.1\|2115061_2115448_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_020444755.1\|2119682_2120996_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	unknown	unknown	gnl\|CDD\|223840
NZ_CP012018.1\|WP_000180461.1\|2109982_2110183_-\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000949467.1\|2121287_2121788_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
NZ_CP012018.1\|WP_000544969.1\|2118949_2119681_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
NZ_CP012018.1\|WP_000140176.1\|2122798_2123869_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP012018.1\|WP_001795438.1\|2108723_2109980_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_CP012018.1\|WP_020444755.1\|2119682_2120996_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	2.82308e-99
NZ_CP012018.1\|WP_000548781.1\|2124115_2124646_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
NZ_CP012018.1\|WP_000999713.1\|2116894_2117881_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
NZ_CP012018.1\|WP_001017131.1\|2113305_2114349_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
NZ_CP012018.1\|WP_000153530.1\|2112686_2113316_-\|two-component-system-response-regulator-VraR	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
NZ_CP012018.1\|WP_000149064.1\|2114345_2115047_-\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
NZ_CP012018.1\|WP_000613733.1\|2122176_2122731_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	1.92778e-75
NZ_CP012018.1\|WP_000636142.1\|2115664_2116423_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
NZ_CP012018.1\|WP_000037075.1\|2111353_2112571_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
NZ_CP012018.1\|WP_000228666.1\|2110329_2110794_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NZ_CP012018.1\|WP_000180461.1\|2109982_2110183_-\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	2.44511e-24

>NZ_CP012018.1|WP_000636142.1|2115664_2116423_-|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NZ_CP012018.1|WP_001110179.1|2115061_2115448_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NZ_CP012018.1|WP_000149064.1|2114345_2115047_-|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NZ_CP012018.1|WP_001017131.1|2113305_2114349_-|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NZ_CP012018.1|WP_000153530.1|2112686_2113316_-|two-component-system-response-regulator-VraR
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NZ_CP012018.1|WP_000037075.1|2111353_2112571_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NZ_CP012018.1|WP_000428172.1|2110800_2111076_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NZ_CP012018.1|WP_000228666.1|2110329_2110794_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NZ_CP012018.1|WP_000180461.1|2109982_2110183_-|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHE
>NZ_CP012018.1|WP_001795438.1|2108723_2109980_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAGKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>NZ_CP012018.1|WP_000999713.1|2116894_2117881_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>NZ_CP012018.1|WP_001549145.1|2118311_2118725_-|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDCDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>NZ_CP012018.1|WP_001790257.1|2118753_2118864_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_CP012018.1|WP_000544969.1|2118949_2119681_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>NZ_CP012018.1|WP_020444755.1|2119682_2120996_-|lipid-II-isoglutaminyl-synthase-subunit-MurT
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHVHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVKVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_CP012018.1|WP_000949467.1|2121287_2121788_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_CP012018.1|WP_001790679.1|2121869_2121962_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP012018.1|WP_000613733.1|2122176_2122731_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP012018.1|WP_000140176.1|2122798_2123869_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP012018.1|WP_000548781.1|2124115_2124646_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ

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Crispr_ID: NZ_CP012018_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_9

2356780-2356930

Orphan

Consensus_repeat	Method
AACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of NZ_CP012018_9

>merge|NZ_CP012018|9|2356780-2356930|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCTTTCTA

>NZ_CP012018|9|9|2356780-2356930|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTTTTA
AACTTTAGTTGTTAGGGGCTCTTATGCA	GTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTC
AACTTTAGTTGTTAGGGGCTTCTTTCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_000495671.1\|2355670_2356762_+\|lytic-regulatory-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000115564.1\|2358052_2359189_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_CP012018.1\|WP_000334465.1\|2362213_2364019_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP012018.1\|WP_000083807.1\|2364699_2366238_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP012018.1\|WP_001024094.1\|2353285_2353951_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP012018.1\|WP_001127960.1\|2351912_2352851_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP012018.1\|WP_000003759.1\|2354102_2354423_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP012018.1\|WP_001292149.1\|2368416_2368851_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP012018.1\|WP_000123393.1\|2349606_2350980_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP012018.1\|WP_000908176.1\|2361199_2361982_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP012018.1\|WP_001790138.1\|2359477_2359570_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000648718.1\|2368850_2369957_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP012018.1\|WP_001123303.1\|2348735_2349149_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP012018.1\|WP_000370924.1\|2360274_2361132_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP012018.1\|WP_000927363.1\|2366272_2368405_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP012018.1\|WP_000070866.1\|2348092_2348536_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP012018.1\|WP_000019744.1\|2354424_2355405_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP012018.1\|WP_001802298.1\|2357261_2357366_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000808817.1\|2351651_2351882_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000160304.1\|2347261_2347972_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000115564.1\|2358052_2359189_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.91533e-06
NZ_CP012018.1\|WP_000334465.1\|2362213_2364019_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP012018.1\|WP_000083807.1\|2364699_2366238_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP012018.1\|WP_001024094.1\|2353285_2353951_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.74381e-48
NZ_CP012018.1\|WP_001127960.1\|2351912_2352851_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP012018.1\|WP_000003759.1\|2354102_2354423_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP012018.1\|WP_001292149.1\|2368416_2368851_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP012018.1\|WP_000123393.1\|2349606_2350980_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_CP012018.1\|WP_000908176.1\|2361199_2361982_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	4.88024e-103
NZ_CP012018.1\|WP_000648718.1\|2368850_2369957_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP012018.1\|WP_000370924.1\|2360274_2361132_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59
NZ_CP012018.1\|WP_000927363.1\|2366272_2368405_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67
NZ_CP012018.1\|WP_000070866.1\|2348092_2348536_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP012018.1\|WP_000019744.1\|2354424_2355405_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
NZ_CP012018.1\|WP_001123303.1\|2348735_2349149_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_CP012018.1\|WP_000160304.1\|2347261_2347972_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157

>NZ_CP012018.1|WP_000495671.1|2355670_2356762_+|lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP012018.1|WP_000019744.1|2354424_2355405_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP012018.1|WP_000003759.1|2354102_2354423_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP012018.1|WP_001024094.1|2353285_2353951_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>NZ_CP012018.1|WP_001127960.1|2351912_2352851_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP012018.1|WP_000808817.1|2351651_2351882_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP012018.1|WP_000123393.1|2349606_2350980_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP012018.1|WP_001123303.1|2348735_2349149_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP012018.1|WP_000070866.1|2348092_2348536_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP012018.1|WP_000160304.1|2347261_2347972_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP012018.1|WP_001802298.1|2357261_2357366_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP012018.1|WP_000115564.1|2358052_2359189_-|SAP-domain-containing-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYVVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>NZ_CP012018.1|WP_001790138.1|2359477_2359570_+|hypothetical-protein
MFIFKTTSKSHFHNNVKSLECIKIPINKNR
>NZ_CP012018.1|WP_000370924.1|2360274_2361132_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>NZ_CP012018.1|WP_000908176.1|2361199_2361982_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMFAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP012018.1|WP_000334465.1|2362213_2364019_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP012018.1|WP_000083807.1|2364699_2366238_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP012018.1|WP_000927363.1|2366272_2368405_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP012018.1|WP_001292149.1|2368416_2368851_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP012018.1|WP_000648718.1|2368850_2369957_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

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Crispr_ID: NZ_CP012018_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_10

2482272-2482465

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of NZ_CP012018_10

>merge|NZ_CP012018|10|2482272-2482465|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>NZ_CP012018|10|1|2482272-2482465|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTAAGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_001790034.1\|2482041_2482212_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000643988.1\|2483648_2484248_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP012018.1\|WP_020444778.1\|2473712_2476880_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP012018.1\|WP_000913019.1\|2488965_2489571_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP012018.1\|WP_000230173.1\|2482606_2483629_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP012018.1\|WP_000866971.1\|2484254_2484488_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP012018.1\|WP_000602937.1\|2484953_2485439_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP012018.1\|WP_000184419.1\|2480252_2481464_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP012018.1\|WP_000808500.1\|2484493_2484940_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP012018.1\|WP_001549681.1\|2478650_2478902_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000259718.1\|2485435_2486695_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP012018.1\|WP_000076929.1\|2487790_2488795_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NZ_CP012018.1\|WP_000051206.1\|2472799_2472964_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000134528.1\|2486757_2487252_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP012018.1\|WP_000503817.1\|2487253_2487760_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP012018.1\|WP_000600967.1\|2478893_2479658_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP012018.1\|WP_000413865.1\|2476996_2478262_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP012018.1\|WP_000066900.1\|2481565_2481916_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP012018.1\|WP_001161085.1\|2473208_2473526_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_000951058.1\|2479819_2480260_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000643988.1\|2483648_2484248_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP012018.1\|WP_000913019.1\|2488965_2489571_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NZ_CP012018.1\|WP_020444778.1\|2473712_2476880_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP012018.1\|WP_000230173.1\|2482606_2483629_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP012018.1\|WP_000602937.1\|2484953_2485439_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NZ_CP012018.1\|WP_000866971.1\|2484254_2484488_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP012018.1\|WP_000808500.1\|2484493_2484940_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_CP012018.1\|WP_000184419.1\|2480252_2481464_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72
NZ_CP012018.1\|WP_000076929.1\|2487790_2488795_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
NZ_CP012018.1\|WP_000134528.1\|2486757_2487252_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.63862e-98
NZ_CP012018.1\|WP_000503817.1\|2487253_2487760_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	1.02752e-64
NZ_CP012018.1\|WP_000600967.1\|2478893_2479658_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NZ_CP012018.1\|WP_000413865.1\|2476996_2478262_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
NZ_CP012018.1\|WP_000066900.1\|2481565_2481916_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP012018.1\|WP_000259718.1\|2485435_2486695_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
NZ_CP012018.1\|WP_000951058.1\|2479819_2480260_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15

>NZ_CP012018.1|WP_001790034.1|2482041_2482212_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NZ_CP012018.1|WP_000066900.1|2481565_2481916_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP012018.1|WP_000184419.1|2480252_2481464_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP012018.1|WP_000951058.1|2479819_2480260_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP012018.1|WP_000600967.1|2478893_2479658_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP012018.1|WP_001549681.1|2478650_2478902_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NZ_CP012018.1|WP_000413865.1|2476996_2478262_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP012018.1|WP_020444778.1|2473712_2476880_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMLTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP012018.1|WP_001161085.1|2473208_2473526_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP012018.1|WP_000051206.1|2472799_2472964_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP012018.1|WP_000230173.1|2482606_2483629_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP012018.1|WP_000643988.1|2483648_2484248_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP012018.1|WP_000866971.1|2484254_2484488_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP012018.1|WP_000808500.1|2484493_2484940_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP012018.1|WP_000602937.1|2484953_2485439_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP012018.1|WP_000259718.1|2485435_2486695_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP012018.1|WP_000134528.1|2486757_2487252_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NZ_CP012018.1|WP_000503817.1|2487253_2487760_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIDGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP012018.1|WP_000076929.1|2487790_2488795_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP012018.1|WP_000913019.1|2488965_2489571_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP012018_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012018_11

2981817-2981900

Orphan

Consensus_repeat	Method
TTTCGAAATTCTCTGTGTTGGGACCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012018_11

>merge|NZ_CP012018|11|2981817-2981900|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGACCCACACCCTAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCC

>NZ_CP012018|11|10|2981817-2981900|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGACCC	ACACCCTAACTCGCATTGCCTGTAGAATTTCT
TTTCGAAATTCTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012018.1\|WP_059283891.1\|2973796_2975677_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	unknown	unknown	gnl\|CDD\|376899
NZ_CP012018.1\|WP_000491382.1\|2981212_2981566_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NZ_CP012018.1\|WP_000089284.1\|2978313_2979117_-\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173803
NZ_CP012018.1\|WP_000362509.1\|2985663_2987043_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_CP012018.1\|WP_000672024.1\|2975768_2975960_+\|peptide-resistance-ABC-transporter-activity-modulator-VraH	unknown	unknown	unknown
NZ_CP012018.1\|WP_000215590.1\|2983000_2983720_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NZ_CP012018.1\|WP_000779134.1\|2980749_2981145_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NZ_CP012018.1\|WP_000790915.1\|2977545_2978295_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373922
NZ_CP012018.1\|WP_001789343.1\|2987186_2987540_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
NZ_CP012018.1\|WP_001059079.1\|2979600_2979801_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_CP012018.1\|WP_000586234.1\|2977046_2977544_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012018.1\|WP_020444822.1\|2973048_2973807_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	unknown	unknown	gnl\|CDD\|224059
NZ_CP012018.1\|WP_000742839.1\|2982118_2982958_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NZ_CP012018.1\|WP_000249657.1\|2983719_2985597_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NZ_CP012018.1\|WP_000240855.1\|2987659_2987797_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NZ_CP012018.1\|WP_001054111.1\|2979927_2980497_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045

Protein	Function_ID	Function_description	E-value
NZ_CP012018.1\|WP_000249657.1\|2983719_2985597_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NZ_CP012018.1\|WP_000491382.1\|2981212_2981566_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.35852e-38
NZ_CP012018.1\|WP_000089284.1\|2978313_2979117_-\|S8-family-serine-peptidase	gnl\|CDD\|173803	cd07477, Peptidases_S8_Subtilisin_subset, Peptidase S8 family domain in Subtilisin proteins. This group is composed of many different subtilisins: Pro-TK-subtilisin, subtilisin Carlsberg, serine protease Pb92 subtilisin, and BPN subtilisins just to name a few. Pro-TK-subtilisin is a serine protease from the hyperthermophilic archaeon Thermococcus kodakaraensis and consists of a signal peptide, a propeptide, and a mature domain. TK-subtilisin is matured from pro-TK-subtilisin upon autoprocessing and degradation of the propeptide. Unlike other subtilisins though, the folding of the unprocessed form of pro-TK-subtilisin is induced by Ca2+ binding which is almost completed prior to autoprocessing. Ca2+ is required for activity unlike the bacterial subtilisins. The propeptide is not required for folding of the mature domain unlike the bacterial subtilases because of the stability produced from Ca2+ binding. Subtilisin Carlsberg is extremely similar in structure to subtilisin BPN'/Novo thought it has a 30% difference in amino acid sequence. The substrate binding regions are also similar and 2 possible Ca2+ binding sites have been identified recently. Subtilisin Carlsberg possesses the highest commercial importance as a proteolytic additive for detergents. Serine protease Pb92, the serine protease from the alkalophilic Bacillus strain PB92, also contains two calcium ions and the overall folding of the polypeptide chain closely resembles that of the subtilisins. Members of the peptidases S8 and S35 clan include endopeptidases, exopeptidases and also a tripeptidyl-peptidase. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The S53 family contains a catalytic triad Glu/Asp/Ser. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.02571e-48
NZ_CP012018.1\|WP_000742839.1\|2982118_2982958_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	4.59236e-111
NZ_CP012018.1\|WP_059283891.1\|2973796_2975677_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.23456e-06
NZ_CP012018.1\|WP_000779134.1\|2980749_2981145_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	5.93989e-39
NZ_CP012018.1\|WP_000790915.1\|2977545_2978295_-\|hypothetical-protein	gnl\|CDD\|373922	pfam15526, Ntox21, Novel toxin 21. Bacterial genomes and plasmids encode a variety of peptide and protein toxins that mediate inter-bacterial competition. Bacteriocins are diffusible proteins that parasitize cell-envelope proteins to enter and kill bacteria. Contact-dependent growth inhibition (CDI) is one mechanism of inter-bacterial competition. Novel Toxin 21 (alternatively 16S rRNA endonuclease CdiA) belongs to a family of prokaryotic polymorphic toxin systems implicated in intra-specific conflicts. This RNase toxin found in bacterial polymorphic toxin systems, is proposed to adopt the BECR (Barnase-EndoU-ColicinE5/D-RelE) fold, with two conserved lysine residues and [DS]xDxxxH, RxG[ST] and RxxD motifs. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 4, type 5 or type 7 secretion systems. This is also referred to as the E. cloacae CdiAC. The CdiAC proteins carry a variety of sequence-diverse C-terminal domains, which represent a collection of distinct toxins. Many CdiA-CT toxins have nuclease activities. In accord with the structural homology, CdiA-CT cleaves 16S rRNA at the same site as colicin E3 and this nuclease activity is responsible for growth inhibition.	3.28374e-23
NZ_CP012018.1\|WP_001789343.1\|2987186_2987540_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	3.11548e-51
NZ_CP012018.1\|WP_001059079.1\|2979600_2979801_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.4289e-30
NZ_CP012018.1\|WP_020444822.1\|2973048_2973807_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	9.8307e-108
NZ_CP012018.1\|WP_000215590.1\|2983000_2983720_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	3.53317e-96
NZ_CP012018.1\|WP_000362509.1\|2985663_2987043_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_CP012018.1\|WP_000240855.1\|2987659_2987797_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	8.39798e-10
NZ_CP012018.1\|WP_001054111.1\|2979927_2980497_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.78153e-16

>NZ_CP012018.1|WP_000491382.1|2981212_2981566_-|DUF3147-family-protein
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLTSLYIKHKGYRKGAIFTVVCWFVISLAIFSIRHL
>NZ_CP012018.1|WP_000779134.1|2980749_2981145_-|DUF3147-family-protein
MKLTLMKFFVGGFAVLLSYIVSVTLPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGFLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKSNSK
>NZ_CP012018.1|WP_001054111.1|2979927_2980497_-|helix-turn-helix-transcriptional-regulator
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCDLFNVTLDDLVKGTIPFAPDIKAQRSLNLWTYVMLIFMTLAAILTGPLVVYWNWAWGITVIVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTGVLSFIAFVGAIILIALISMHLANKFL
>NZ_CP012018.1|WP_001059079.1|2979600_2979801_+|cold-shock-protein
MNNGTVKWFNAEKGFGFIEQENGGDVFVHFSGIASDGYKTLEEGQKVTFEITEGQRGDQAVNVQTV
>NZ_CP012018.1|WP_000089284.1|2978313_2979117_-|S8-family-serine-peptidase
MSRNLIHLSIGVAIFIISFSFYLLNQPNNWAWSSLNICINDSKPSNVKVAILDTGINNTRINNNFVTKRYNAINNHNQITTDSNHATQVASIITYGEHKEKLIGISKSVSIYDVKVLDDNLKGDIDNIIKGITWSIKNDVNIIHMSFGFQRYNKELHDAIKNAKNKGIILVAAAGNNMDDYSDYPARFNEVYSITAIDKNNKPFIYAPTKKIDFKAPGVDVYTKGSKDELLTVNGTSFAAAYFTAYLTNNLEFRNDLPHILKEYPIK
>NZ_CP012018.1|WP_000790915.1|2977545_2978295_-|hypothetical-protein
MKNKIIILFLAIIITFTYGNFAEASVVIKEANINNSNSKINTNKINENIYSKNNRNYIDNNFKSKDLNIESSLEHDLNTDKITVDASLKDNYNNKLDKTYDVKFLRIVNENDFKAEFTDQDTGEKIIYDTNEVKASIAPVVAVLVGFIAKQGLKKAIQKYGKTVVTSMIRTSPQVAAQAAKKLGYSATKHVSHGKKVFKKNSKGRPQYISVDKDGHRGGAWKGASSIKNLGSKKTRSGTYDANLKRIGD
>NZ_CP012018.1|WP_000586234.1|2977046_2977544_-|hypothetical-protein
MIINLETQQIHFDLEHEIPYFQSPEKNRIRLDIDVLNKKQISNIINVIFNNQSKTKCTFLSEYLYPVKFREKTRIGRFFNITNWYEEIHSADEKYVIATIKNIKNKDLIDYSLYIKKGLVEPFIVFYNQENIFYISNAVIDIISVSKDTLGYIKSEFNDHCASPY
>NZ_CP012018.1|WP_000672024.1|2975768_2975960_+|peptide-resistance-ABC-transporter-activity-modulator-VraH
MKFRELVKQSYEDLKNLTVTWYNVIALAIIVIVLSTVTTPIIGIPAGLLGGAYYLKRREEKGK
>NZ_CP012018.1|WP_059283891.1|2973796_2975677_+|peptide-resistance-ABC-transporter-permease-subunit-VraE
MTFNHIVLKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILKMLALEQMIVFIITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTILMLIIAYILILFQSSLFLKRRSILSMMKDSVKTDVTTAKVTVIEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSTMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNDFNVVASQDAQQFESKLSQQHITFSKNYYETITVDNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNVINIHLNNDLVVKGTKNETFRVTQEDKDKVYPLNLSFNSPVIEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKKKAQAIAKQFGDKIITYDDMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>NZ_CP012018.1|WP_020444822.1|2973048_2973807_+|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFHKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHKPQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVKVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI
>NZ_CP012018.1|WP_000742839.1|2982118_2982958_-|ParB/RepB/Spo0J-family-partition-protein
MKKPFSKLFGLKNKDDIIGHIEENRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFEQDVTQARDEVGKSIQAIQQIGLHVEHKDKDHEDYYEIKIRIYKR
>NZ_CP012018.1|WP_000215590.1|2983000_2983720_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNYLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>NZ_CP012018.1|WP_000249657.1|2983719_2985597_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>NZ_CP012018.1|WP_000362509.1|2985663_2987043_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>NZ_CP012018.1|WP_001789343.1|2987186_2987540_-|ribonuclease-P-protein-component
MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>NZ_CP012018.1|WP_000240855.1|2987659_2987797_-|50S-ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP012018_5	5.1\|920551\|34\|NZ_CP012018\|CRISPRCasFinder	920551-920584	34	NZ_CP012018.1	1455826-1455859	0	1.0
NZ_CP012018_5	5.1\|920551\|34\|NZ_CP012018\|CRISPRCasFinder	920551-920584	34	NZ_CP012018.1	1548413-1548446	0	1.0
NZ_CP012018_10	10.2\|2482351\|36\|NZ_CP012018\|CRT	2482351-2482386	36	NZ_CP012018.1	1244933-1244968	0	1.0
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	390247-390275	1	0.966
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	390302-390330	1	0.966
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	1959412-1959440	1	0.966
NZ_CP012018_7	7.1\|1245032\|26\|NZ_CP012018\|CRISPRCasFinder	1245032-1245057	26	NZ_CP012018.1	311846-311871	1	0.962
NZ_CP012018_7	7.1\|1245032\|26\|NZ_CP012018\|CRISPRCasFinder	1245032-1245057	26	NZ_CP012018.1	839177-839202	1	0.962
NZ_CP012018_7	7.1\|1245032\|26\|NZ_CP012018\|CRISPRCasFinder	1245032-1245057	26	NZ_CP012018.1	876129-876154	1	0.962
NZ_CP012018_10	10.2\|2482351\|36\|NZ_CP012018\|CRT	2482351-2482386	36	NZ_CP012018.1	1959405-1959440	1	0.972
NZ_CP012018_11	11.1\|2981843\|32\|NZ_CP012018\|CRISPRCasFinder	2981843-2981874	32	NZ_CP012018.1	876209-876240	1	0.969
NZ_CP012018_11	11.1\|2981843\|32\|NZ_CP012018\|CRISPRCasFinder	2981843-2981874	32	NZ_CP012018.1	1127005-1127036	1	0.969
NZ_CP012018_11	11.1\|2981843\|32\|NZ_CP012018\|CRISPRCasFinder	2981843-2981874	32	NZ_CP012018.1	1548503-1548534	1	0.969
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	311978-312006	2	0.931
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	920593-920621	2	0.931
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	1003287-1003315	2	0.931
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	1244940-1244968	2	0.931
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	1773405-1773433	2	0.931
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	2127317-2127345	2	0.931
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	NZ_CP012018.1	2678272-2678300	2	0.931
NZ_CP012018_7	7.1\|1245032\|26\|NZ_CP012018\|CRISPRCasFinder	1245032-1245057	26	NZ_CP012018.1	839121-839146	2	0.923
NZ_CP012018_7	7.1\|1245032\|26\|NZ_CP012018\|CRISPRCasFinder	1245032-1245057	26	NZ_CP012018.1	839233-839258	2	0.923
NZ_CP012018_10	10.1\|2482295\|33\|NZ_CP012018\|CRT	2482295-2482327	33	NZ_CP012018.1	1244989-1245021	2	0.939
NZ_CP012018_10	10.1\|2482295\|33\|NZ_CP012018\|CRT	2482295-2482327	33	NZ_CP012018.1	1455781-1455813	2	0.939
NZ_CP012018_10	10.1\|2482295\|33\|NZ_CP012018\|CRT	2482295-2482327	33	NZ_CP012018.1	1548459-1548491	2	0.939
NZ_CP012018_10	10.1\|2482295\|33\|NZ_CP012018\|CRT	2482295-2482327	33	NZ_CP012018.1	2759051-2759083	2	0.939
NZ_CP012018_10	10.2\|2482351\|36\|NZ_CP012018\|CRT	2482351-2482386	36	NZ_CP012018.1	311971-312006	2	0.944
NZ_CP012018_10	10.2\|2482351\|36\|NZ_CP012018\|CRT	2482351-2482386	36	NZ_CP012018.1	1773405-1773440	2	0.944
NZ_CP012018_10	10.2\|2482351\|36\|NZ_CP012018\|CRT	2482351-2482386	36	NZ_CP012018.1	2127317-2127352	2	0.944
NZ_CP012018_10	10.3\|2482410\|33\|NZ_CP012018\|CRT	2482410-2482442	33	NZ_CP012018.1	876109-876141	2	0.939
NZ_CP012018_10	10.3\|2482410\|33\|NZ_CP012018\|CRT	2482410-2482442	33	NZ_CP012018.1	1244989-1245021	2	0.939
NZ_CP012018_10	10.3\|2482410\|33\|NZ_CP012018\|CRT	2482410-2482442	33	NZ_CP012018.1	1455781-1455813	2	0.939
NZ_CP012018_10	10.3\|2482410\|33\|NZ_CP012018\|CRT	2482410-2482442	33	NZ_CP012018.1	2759051-2759083	2	0.939

1. spacer 5.1|920551|34|NZ_CP012018|CRISPRCasFinder matches to position: 1455826-1455859, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

2. spacer 5.1|920551|34|NZ_CP012018|CRISPRCasFinder matches to position: 1548413-1548446, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 10.2|2482351|36|NZ_CP012018|CRT matches to position: 1244933-1244968, mismatch: 0, identity: 1.0

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttctttttgaaattctcta	Protospacer
************************************

4. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 390247-390275, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

5. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 390302-390330, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

6. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 1959412-1959440, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

7. spacer 7.1|1245032|26|NZ_CP012018|CRISPRCasFinder matches to position: 311846-311871, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cgggcccccaacatagaagctggcgg	Protospacer
**** *********************

8. spacer 7.1|1245032|26|NZ_CP012018|CRISPRCasFinder matches to position: 839177-839202, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagcaggcgg	Protospacer
******************** *****

9. spacer 7.1|1245032|26|NZ_CP012018|CRISPRCasFinder matches to position: 876129-876154, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctggcgg	Protospacer
*************.************

10. spacer 10.2|2482351|36|NZ_CP012018|CRT matches to position: 1959405-1959440, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

11. spacer 11.1|2981843|32|NZ_CP012018|CRISPRCasFinder matches to position: 876209-876240, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

12. spacer 11.1|2981843|32|NZ_CP012018|CRISPRCasFinder matches to position: 1127005-1127036, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

13. spacer 11.1|2981843|32|NZ_CP012018|CRISPRCasFinder matches to position: 1548503-1548534, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

14. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 311978-312006, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

15. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 920593-920621, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

16. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 1003287-1003315, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

17. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 1244940-1244968, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttctttttgaaa	Protospacer
********.***************.****

18. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 1773405-1773433, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

19. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 2127317-2127345, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaa	Protospacer
********.***********.********

20. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to position: 2678272-2678300, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

21. spacer 7.1|1245032|26|NZ_CP012018|CRISPRCasFinder matches to position: 839121-839146, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*************.****** *****

22. spacer 7.1|1245032|26|NZ_CP012018|CRISPRCasFinder matches to position: 839233-839258, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacataaaagcaggcgg	Protospacer
***************.**** *****

23. spacer 10.1|2482295|33|NZ_CP012018|CRT matches to position: 1244989-1245021, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

24. spacer 10.1|2482295|33|NZ_CP012018|CRT matches to position: 1455781-1455813, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

25. spacer 10.1|2482295|33|NZ_CP012018|CRT matches to position: 1548459-1548491, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

26. spacer 10.1|2482295|33|NZ_CP012018|CRT matches to position: 2759051-2759083, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

27. spacer 10.2|2482351|36|NZ_CP012018|CRT matches to position: 311971-312006, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

28. spacer 10.2|2482351|36|NZ_CP012018|CRT matches to position: 1773405-1773440, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

29. spacer 10.2|2482351|36|NZ_CP012018|CRT matches to position: 2127317-2127352, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

30. spacer 10.3|2482410|33|NZ_CP012018|CRT matches to position: 876109-876141, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgactttccgccagcttctg	Protospacer
*********************.*.*********

31. spacer 10.3|2482410|33|NZ_CP012018|CRT matches to position: 1244989-1245021, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

32. spacer 10.3|2482410|33|NZ_CP012018|CRT matches to position: 1455781-1455813, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

33. spacer 10.3|2482410|33|NZ_CP012018|CRT matches to position: 2759051-2759083, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012018_4	4.1\|870727\|29\|NZ_CP012018\|CRISPRCasFinder	870727-870755	29	MN693281	Marine virus AFVG_25M371, complete genome	6448-6476	7	0.759
NZ_CP012018_8	8.1\|2116619\|33\|NZ_CP012018\|CRISPRCasFinder	2116619-2116651	33	NZ_CP009619	Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence	270866-270898	8	0.758

1. spacer 4.1|870727|29|NZ_CP012018|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 7, identity: 0.759

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtaggatttcttctaagtg	Protospacer
**************.*******.* .. .

2. spacer 8.1|2116619|33|NZ_CP012018|CRISPRCasFinder matches to NZ_CP009619 (Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence) position: , mismatch: 8, identity: 0.758

ccaacctgcattgcctgtagaatttcttttttg	CRISPR spacer
aagtgctgcattacctgtagcatttcttttttc	Protospacer
  .  *******.******* ***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

44361 : 84386

Streptococcus_phage(37.5%)

transposase,integrase

attL 43846:43862|attR 85163:85179

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
43846:43862	attL	NA	NA	NA	NA
WP_000868132.1\|44361_45447_+\|integrase	tyrosine-type recombinase/integrase	A0A0A8WIF9	Clostridium_phage	4.5e-12	28.3
WP_000361060.1\|47343_47721_+\|transposase	transposase	NA	NA	NA	NA
WP_001072201.1\|48779_49511_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	E4ZFQ0	Streptococcus_phage	1.9e-51	47.5
WP_010959190.1\|49593_49653_-	erythromycin resistance leader peptide	NA	NA	NA	NA
WP_001092058.1\|50044_50707_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_000373151.1\|51254_52127_+	HTH domain-containing protein	NA	NA	NA	NA
WP_000065262.1\|52183_52474_+	hypothetical protein	NA	NA	NA	NA
WP_000397419.1\|52489_52978_+	hypothetical protein	NA	NA	NA	NA
WP_000717928.1\|53112_53640_+	hypothetical protein	NA	NA	NA	NA
WP_000941331.1\|53701_54118_+	hypothetical protein	NA	NA	NA	NA
WP_001803222.1\|54406_54571_+	hypothetical protein	NA	NA	NA	NA
WP_001070883.1\|54584_54806_+	hypothetical protein	NA	NA	NA	NA
WP_020444591.1\|54941_55520_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_001824952.1\|55599_57828_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.8e-44	26.6
WP_001105999.1\|57874_58549_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	2.0e-127	99.1
WP_000163428.1\|58831_60178_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_000425271.1\|60477_60885_+	Hg(II)-responsive transcriptional regulator MerR	NA	NA	NA	NA
WP_000010351.1\|61252_61933_+	cytochrome c biosynthesis protein	NA	NA	NA	NA
WP_000968575.1\|62067_62406_+	hypothetical protein	NA	NA	NA	NA
WP_000193219.1\|62463_64107_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.7e-50	29.4
WP_020444593.1\|64188_64839_+	organomercurial lyase MerB	NA	NA	NA	NA
WP_041205518.1\|65033_65564_-	hypothetical protein	NA	NA	NA	NA
WP_001106057.1\|65599_66274_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	2.6e-127	99.1
WP_000958858.1\|67615_68359_+	glycerophosphoryl diester phosphodiesterase	NA	NA	NA	NA
WP_000872606.1\|68455_68884_+	MaoC family dehydratase	NA	NA	NA	NA
WP_078056052.1\|68929_70939_-	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	NA	NA	NA	NA
WP_000952923.1\|71035_72793_+	beta-lactam sensor/signal transducer MecR1	NA	NA	NA	NA
WP_014532405.1\|73248_73317_-	phenol-soluble modulin PSM-mec	NA	NA	NA	NA
WP_000427807.1\|73635_74784_+	ROK family transcriptional regulator	NA	NA	NA	NA
WP_000438836.1\|76263_77328_-	DsrE/DsrF/DrsH-like family protein	NA	NA	NA	NA
WP_000220507.1\|77463_77724_+	persulfide-sensing transcriptional repressor CstR	NA	NA	NA	NA
WP_000350222.1\|77723_78368_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_000562107.1\|78635_79253_-	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_053038472.1\|79333_81514_-	cadmium-translocating P-type ATPase CadA	E4ZFI9	Streptococcus_phage	5.4e-251	63.2
WP_000159127.1\|81506_81872_-	winged helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	7.7e-25	49.6
WP_000361059.1\|82109_82487_-\|transposase	transposase	NA	NA	NA	NA
WP_059283841.1\|82493_84386_-\|integrase	phage integrase family protein	NA	NA	NA	NA
85163:85179	attR	NA	NA	NA	NA

DBSCAN-SWA_2

402609 : 412949

Streptococcus_phage(80.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000284571.1\|402609_404214_+\|transposase	IS1182-like element IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.1e-128	44.4
WP_000567888.1\|404339_404585_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_000228166.1\|404687_405557_+	nucleotidyltransferase domain-containing protein	A0A1X9I6C9	Streptococcus_phage	4.3e-159	95.8
WP_000662263.1\|405537_406272_+	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
WP_001255866.1\|406304_407213_+	aminoglycoside nucleotidyltransferase ANT(6)-Ia	E4ZFP8	Streptococcus_phage	2.8e-177	100.0
WP_000627289.1\|407209_407740_+	streptothricin N-acetyltransferase Sat4	A0A1B0RXL7	Streptococcus_phage	1.3e-89	97.8
WP_001096887.1\|407832_408627_+	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
WP_001079938.1\|408902_409475_+	HTH domain-containing protein	A0A1B0RXM1	Streptococcus_phage	5.5e-102	99.5
WP_072387101.1\|409447_409855_+	WYL domain-containing protein	A0A1B0RXM3	Streptococcus_phage	1.1e-59	98.3
WP_000802831.1\|409965_410625_+	RibD family protein	A0A1B0RXM8	Streptococcus_phage	3.1e-125	100.0
WP_000284571.1\|411344_412949_-\|transposase	IS1182-like element IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.1e-128	44.4

DBSCAN-SWA_3

448574 : 464588

Streptococcus_phage(76.92%)

integrase

attL 444482:444496|attR 460412:460426

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
444482:444496	attL	NA	NA	NA	NA
WP_000264071.1\|448574_450041_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
WP_000424966.1\|450065_451607_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	32.6
WP_000237797.1\|451674_452868_-\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	8.3e-44	34.2
WP_000633907.1\|452894_453095_-	DUF3173 domain-containing protein	NA	NA	NA	NA
WP_000845143.1\|453592_453823_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	1.0e-27	78.9
WP_042857144.1\|453819_454242_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.4e-46	67.9
WP_001227350.1\|454772_455126_+	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	2.2e-53	89.7
WP_032506803.1\|455183_455372_-	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	7.4e-16	61.4
WP_000691737.1\|455469_457389_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.2
WP_000584387.1\|457766_458696_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-83	56.6
WP_059283865.1\|458712_459735_-	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	4.1e-132	75.5
WP_000192392.1\|459731_461759_-	membrane protein	A0A1S5SF30	Streptococcus_phage	2.3e-195	65.5
460412:460426	attR	NA	NA	NA	NA
WP_000331168.1\|461755_464209_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	78.8
WP_000723887.1\|464192_464588_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	5.9e-47	72.6

DBSCAN-SWA_4

467740 : 475906

Streptococcus_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000870467.1\|467740_468235_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	2.8e-54	63.4
WP_000675717.1\|468301_469081_-	abortive infection family protein	NA	NA	NA	NA
WP_001009054.1\|469122_469344_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	3.1e-29	93.2
WP_000055376.1\|469340_469631_-	hypothetical protein	NA	NA	NA	NA
WP_020444628.1\|469627_470812_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.2e-159	67.9
WP_001130245.1\|470992_472396_-	DUF87 domain-containing protein	A0A1S5SFB5	Streptococcus_phage	7.5e-177	66.7
WP_000185761.1\|472417_473191_-	hypothetical protein	NA	NA	NA	NA
WP_001234191.1\|473200_473578_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	9.6e-47	76.4
WP_000421279.1\|473598_473913_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	1.2e-42	77.7
WP_000181735.1\|474112_475906_-	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	6.9e-26	23.8

DBSCAN-SWA_5

809914 : 815576

Streptococcus_virus(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001062972.1\|809914_810628_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|810631_811051_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|811052_811721_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000284571.1\|811909_813514_-\|transposase	IS1182-like element IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.1e-128	44.4
WP_000604514.1\|813847_814441_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001217785.1\|814424_815576_+	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_6

827548 : 842335

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1\|827548_828607_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197271.1\|828957_829500_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429014.1\|830179_831097_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
WP_001790641.1\|831187_831289_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|831366_832872_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|833212_833713_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068503.1\|833732_834599_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|835399_835798_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|835760_837866_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|837983_838955_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|839468_839624_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|839662_840634_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|840620_841577_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616842.1\|841573_842335_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_7

924785 : 936742

Staphylococcus_phage(86.67%)

capsid,terminase,coat,integrase

attL 924624:924642|attR 939030:939048

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
924624:924642	attL	NA	NA	NA	NA
WP_020444648.1\|924785_926006_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	8.4e-100	47.5
WP_001637664.1\|926019_927408_-	SAP domain-containing protein	NA	NA	NA	NA
WP_001186979.1\|927434_928007_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000560872.1\|928178_928400_+	helix-turn-helix transcriptional regulator	A0A2H4JFN1	uncultured_Caudovirales_phage	2.0e-07	43.5
WP_000124597.1\|928400_928673_+	helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	7.7e-38	84.4
WP_000784891.1\|928684_928840_+	hypothetical protein	NA	NA	NA	NA
WP_001231375.1\|928824_929028_+	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	1.0e-31	100.0
WP_020444649.1\|929029_929413_+	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	4.4e-55	89.0
WP_001103955.1\|929413_929734_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	2.6e-21	51.9
WP_001002711.1\|929798_930668_+	primase C-terminal domain-containing protein	Q4ZE74	Staphylococcus_phage	9.0e-165	96.5
WP_000447459.1\|930681_932391_+	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	0.0e+00	96.1
WP_000356938.1\|932720_933101_+	hypothetical protein	Q4ZE71	Staphylococcus_phage	2.0e-68	97.6
WP_001019777.1\|933097_933739_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	5.3e-114	94.4
WP_001190598.1\|934086_934428_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	3.2e-57	98.2
WP_000846290.1\|934439_935018_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.3e-29	39.5
WP_000448775.1\|935035_935254_+\|capsid	capsid morphogenesis B protein	NA	NA	NA	NA
WP_000771358.1\|935304_935832_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	5.8e-90	97.7
WP_025174984.1\|935963_936176_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	3.2e-31	97.1
WP_001281786.1\|936172_936742_+\|terminase	terminase small subunit	A0A1W6JQF0	Staphylococcus_phage	1.2e-101	98.4
939030:939048	attR	NA	NA	NA	NA

DBSCAN-SWA_8

1102269 : 1110742

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1102269_1102752_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010412.1\|1102738_1103863_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1103866_1104571_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1104570_1104834_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1104835_1105507_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032727.1\|1105499_1107689_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000483713.1\|1107667_1109152_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030812.1\|1109144_1110173_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238664.1\|1110175_1110742_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_9

1162399 : 1221733

Staphylococcus_phage(83.58%)

portal,terminase,tail,plate,capsid,holin,head,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000401377.1\|1162399_1162882_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-28	46.2
WP_000843611.1\|1162943_1164083_-	nucleotidyltransferase	NA	NA	NA	NA
WP_000872158.1\|1164209_1164767_+	DUF177 domain-containing protein	NA	NA	NA	NA
WP_000290472.1\|1164846_1165020_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_000861313.1\|1165136_1166522_-	recombinase family protein	I1W625	Staphylococcus_phage	2.5e-265	100.0
WP_000392109.1\|1166728_1167409_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A2H4PQQ5	Staphylococcus_phage	5.1e-123	100.0
WP_031767738.1\|1167440_1167905_-	toxin	A0A0N9BAX8	Staphylococcus_phage	1.2e-83	98.7
WP_001260487.1\|1167917_1168241_-	helix-turn-helix transcriptional regulator	A0A0H3U2V8	Staphylococcus_phage	2.0e-53	100.0
WP_000272859.1\|1168404_1168653_+	helix-turn-helix transcriptional regulator	A0A2K9VBT6	Staphylococcus_phage	1.7e-39	100.0
WP_031767740.1\|1168665_1169112_+	hypothetical protein	A0A075M4D9	Staphylococcus_phage	1.8e-76	98.0
WP_000939498.1\|1169126_1169270_+	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_000642492.1\|1169259_1169469_-	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
WP_000933363.1\|1169908_1170094_+	helix-turn-helix transcriptional regulator	S4SUN2	Staphylococcus_phage	1.7e-25	100.0
WP_031767742.1\|1170095_1170839_+	phage antirepressor KilAC domain-containing protein	G4KNN1	Staphylococcus_phage	4.7e-138	99.6
WP_000395455.1\|1171014_1171245_-	hypothetical protein	C8CGY3	Staphylococcus_phage	2.3e-35	100.0
WP_000066026.1\|1171424_1171586_+	DUF1270 family protein	C8CGY5	Staphylococcus_phage	2.5e-20	100.0
WP_000291089.1\|1171679_1171940_+	DUF1108 family protein	Q4ZBM7	Staphylococcus_phage	1.2e-43	100.0
WP_001004336.1\|1171952_1172489_+	host-nuclease inhibitor Gam family protein	A0A0F6N4M6	Staphylococcus_phage	1.4e-80	100.0
WP_020444661.1\|1172489_1173137_+	ERF family protein	A0A0F6N3I5	Staphylococcus_phage	2.2e-115	96.7
WP_023180131.1\|1173136_1173553_+	single-stranded DNA-binding protein	G4KNN8	Staphylococcus_phage	7.1e-59	83.7
WP_059283875.1\|1173566_1174241_+	hypothetical protein	A0A1X9H0A9	Staphylococcus_phage	3.2e-125	96.9
WP_016028252.1\|1174350_1175010_-	hypothetical protein	E0Y3Q0	Staphylococcus_virus	1.4e-120	100.0
WP_059283876.1\|1175054_1175825_+	conserved phage C-terminal domain-containing protein	A0A2H4PQI2	Staphylococcus_phage	1.2e-115	99.6
WP_000237153.1\|1176600_1176762_+	hypothetical protein	D2JGK6	Staphylococcus_phage	4.5e-22	100.0
WP_041205435.1\|1176774_1176996_+	DUF3269 family protein	Q9G021	Staphylococcus_phage	6.4e-35	98.6
WP_020444760.1\|1177005_1177410_+	DUF1064 domain-containing protein	G4KNP2	Staphylococcus_phage	8.1e-68	98.5
WP_001187239.1\|1177414_1177600_+	DUF3113 family protein	Q4ZAR6	Staphylococcus_virus	2.4e-27	100.0
WP_000022727.1\|1177963_1178218_+	DUF3310 domain-containing protein	A0A2I6PEN5	Staphylococcus_phage	1.6e-42	100.0
WP_072466103.1\|1178217_1178466_+	hypothetical protein	M9NTB1	Staphylococcus_phage	8.8e-41	98.8
WP_020444668.1\|1178478_1178883_+	hypothetical protein	A0A0E3T8H9	Staphylococcus_phage	2.5e-69	96.2
WP_000979209.1\|1178879_1179227_+	hypothetical protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
WP_001668981.1\|1179223_1179532_+	hypothetical protein	Q4ZBK6	Staphylococcus_phage	1.8e-51	100.0
WP_052998299.1\|1179524_1179776_+	DUF1024 family protein	A0A068A237	Staphylococcus_phage	1.6e-37	96.4
WP_000028423.1\|1179765_1179939_+	hypothetical protein	A0A2H4PQJ2	Staphylococcus_phage	2.3e-24	98.2
WP_000889680.1\|1179939_1180101_+	hypothetical protein	W5R9K6	Staphylococcus_phage	5.4e-23	98.1
WP_031790047.1\|1180115_1180649_+	dUTP diphosphatase	Q4ZBS9	Staphylococcus_virus	1.0e-94	99.4
WP_000195793.1\|1180685_1180874_+	DUF1381 domain-containing protein	A0EWR9	Staphylococcus_virus	3.9e-25	98.4
WP_001125015.1\|1180848_1181049_+	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_001797333.1\|1181051_1181225_+	transcriptional activator RinB	A0A0H3U4U1	Staphylococcus_phage	2.2e-22	96.5
WP_000990002.1\|1181225_1181372_+	hypothetical protein	B2ZYX7	Staphylococcus_phage	4.9e-15	97.9
WP_000058632.1\|1181386_1181806_+	transcriptional regulator	I1W651	Staphylococcus_phage	8.1e-71	100.0
WP_001003271.1\|1181993_1182434_+\|terminase	terminase small subunit	I1W650	Staphylococcus_phage	4.8e-74	100.0
WP_000169946.1\|1182420_1183698_+\|terminase	PBSX family phage terminase large subunit	A0EWS5	Staphylococcus_virus	3.0e-249	100.0
WP_000921875.1\|1183708_1185247_+\|portal	phage portal protein	S4V6D8	Staphylococcus_phage	1.9e-290	99.0
WP_001668926.1\|1185253_1186249_+\|capsid	minor capsid protein	B2ZYY2	Staphylococcus_phage	3.4e-184	100.0
WP_000072202.1\|1186321_1186492_+	hypothetical protein	B2ZYY3	Staphylococcus_phage	6.7e-24	100.0
WP_000392143.1\|1186600_1187221_+	DUF4355 domain-containing protein	B2ZYY4	Staphylococcus_phage	8.6e-77	99.0
WP_000438513.1\|1187234_1188209_+\|capsid	phage major capsid protein	S4V686	Staphylococcus_phage	1.7e-183	100.0
WP_001114085.1\|1188230_1188518_+	hypothetical protein	S4V6D9	Staphylococcus_phage	4.7e-46	100.0
WP_000208960.1\|1188526_1188859_+\|head,tail	phage head-tail connector protein	A0A0F6N3F4	Staphylococcus_phage	5.5e-54	100.0
WP_001268313.1\|1188855_1189158_+	hypothetical protein	A4ZFB6	Staphylococcus_virus	7.4e-50	99.0
WP_001017815.1\|1189157_1189505_+	HK97 gp10 family phage protein	A0A0F6N3F5	Staphylococcus_phage	4.1e-60	100.0
WP_015990319.1\|1189516_1189900_+	hypothetical protein	B2ZYZ0	Staphylococcus_phage	2.6e-68	100.0
WP_031879862.1\|1189918_1190500_+\|tail	phage major tail protein, TP901-1 family	A0A0F6N3L8	Staphylococcus_phage	1.4e-105	99.5
WP_001100163.1\|1190562_1190928_+\|tail	tail assembly chaperone	Q8SDT9	Staphylococcus_phage	2.8e-59	100.0
WP_000105584.1\|1190957_1191302_+	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
WP_031879863.1\|1191318_1194783_+	membrane protein	Q4ZDU6	Staphylococcus_virus	7.8e-268	95.2
WP_031783356.1\|1194795_1195743_+\|tail	phage tail family protein	Q8SDT6	Staphylococcus_phage	1.8e-182	99.0
WP_031768995.1\|1195751_1197653_+\|tail	phage tail protein	I1W634	Staphylococcus_phage	0.0e+00	99.7
WP_029549540.1\|1197667_1199578_+	hypothetical protein	B2ZYZ7	Staphylococcus_phage	0.0e+00	99.7
WP_031794187.1\|1199577_1201401_+\|plate	phage baseplate upper protein	B1H3M3	Staphylococcus_phage	0.0e+00	100.0
WP_000705893.1\|1201400_1201778_+	DUF2977 domain-containing protein	Q8LTH7	Staphylococcus_phage	7.3e-55	100.0
WP_001790193.1\|1201781_1201955_+	XkdX family protein	Q8LTH6	Staphylococcus_phage	1.7e-27	100.0
WP_000466769.1\|1201995_1202295_+	DUF2951 domain-containing protein	Q4ZBP8	Staphylococcus_phage	1.3e-46	100.0
WP_052998263.1\|1202431_1204315_+	glucosaminidase domain-containing protein	A0A0H3U444	Staphylococcus_phage	0.0e+00	96.5
WP_000276641.1\|1204327_1205566_+\|plate	BppU family phage baseplate upper protein	E0Y3M8	Staphylococcus_virus	3.5e-210	100.0
WP_031782932.1\|1205570_1205966_+	hypothetical protein	S4SWE0	Staphylococcus_phage	4.4e-66	96.9
WP_000354128.1\|1206020_1206458_+\|holin	phage holin	S4SVG2	Staphylococcus_phage	4.1e-73	99.3
WP_001148135.1\|1206438_1207884_+	SH3 domain-containing protein	Q4ZB16	Staphylococcus_virus	4.8e-296	100.0
WP_001041586.1\|1208615_1210553_-	heme uptake protein IsdB	NA	NA	NA	NA
WP_000160859.1\|1210755_1211808_-	LPXTG-anchored heme-scavenging protein IsdA	NA	NA	NA	NA
WP_000789821.1\|1212016_1212700_+	heme uptake protein IsdC	NA	NA	NA	NA
WP_001246698.1\|1212699_1213776_+	iron-regulated surface determinant protein IsdD	NA	NA	NA	NA
WP_001220199.1\|1213772_1214651_+	heme ABC transporter substrate-binding protein IsdE	NA	NA	NA	NA
WP_000594530.1\|1214663_1215629_+	hemin ABC transporter permease protein IsdF	NA	NA	NA	NA
WP_001242429.1\|1215691_1216426_+	class B sortase	NA	NA	NA	NA
WP_000670950.1\|1216444_1216768_+	staphylobilin-forming heme oxygenase IsdG	NA	NA	NA	NA
WP_001788617.1\|1216804_1216912_+	hypothetical protein	NA	NA	NA	NA
WP_000435374.1\|1217151_1217892_+	RNA methyltransferase	NA	NA	NA	NA
WP_000003559.1\|1218272_1219331_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5
WP_000908982.1\|1219330_1221733_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA

DBSCAN-SWA_10

1602181 : 1689903

106

Staphylococcus_phage(74.03%)

portal,terminase,tail,plate,protease,capsid,holin,head,tRNA,integrase

attL 1641960:1641977|attR 1688420:1688437

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858789.1\|1602181_1603474_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0
WP_000525078.1\|1603795_1606489_-	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
WP_000049919.1\|1606512_1607484_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000361544.1\|1607470_1608673_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	3.2e-35	42.5
WP_042857062.1\|1608677_1609820_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000839926.1\|1610060_1610378_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_001827022.1\|1610714_1611395_-	zinc metallopeptidase	NA	NA	NA	NA
WP_000152734.1\|1611466_1612054_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_000004947.1\|1612043_1612619_-	YpiB family protein	G3MAV7	Bacillus_virus	2.7e-08	27.2
WP_000389524.1\|1612632_1613877_-	hypothetical protein	NA	NA	NA	NA
WP_000245895.1\|1613883_1615182_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000776323.1\|1615191_1616256_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269929.1\|1616281_1617448_-	chorismate synthase	A0A291AU41	Pandoravirus	7.6e-34	32.1
WP_000789522.1\|1617833_1618034_-	hypothetical protein	NA	NA	NA	NA
WP_000442480.1\|1618242_1618692_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_001096471.1\|1618783_1619743_-	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000774684.1\|1619744_1620470_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_020444684.1\|1620472_1621045_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_001043863.1\|1621475_1621748_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000161738.1\|1621918_1622917_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165530.1\|1622933_1624244_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000133954.1\|1624465_1625641_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_001789944.1\|1625897_1626089_-	hypothetical protein	NA	NA	NA	NA
WP_001789945.1\|1626205_1626322_-	hypothetical protein	NA	NA	NA	NA
WP_000644391.1\|1626352_1627012_-	(d)CMP kinase	NA	NA	NA	NA
WP_000681758.1\|1627088_1628057_+	asparaginase	NA	NA	NA	NA
WP_001174260.1\|1628171_1629158_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_001789943.1\|1629318_1629435_-	hypothetical protein	NA	NA	NA	NA
WP_000069282.1\|1629559_1631020_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_000902119.1\|1631172_1632552_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6
WP_001163801.1\|1632541_1633495_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001151997.1\|1633602_1633851_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001186912.1\|1633956_1634502_-	ECF transporter S component	NA	NA	NA	NA
WP_001789947.1\|1634780_1634900_-	hypothetical protein	NA	NA	NA	NA
WP_000913219.1\|1635098_1636013_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001033757.1\|1636027_1636234_-	hypothetical protein	NA	NA	NA	NA
WP_020444682.1\|1636226_1637165_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476873.1\|1637222_1638140_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000470336.1\|1638230_1638416_-	hypothetical protein	A0ZS61	Staphylococcus_virus	1.7e-25	100.0
WP_000528632.1\|1638691_1639249_-	hypothetical protein	W5R8Q1	Staphylococcus_phage	5.7e-104	100.0
WP_020444681.1\|1639973_1641428_-	N-acetylmuramoyl-L-alanine amidase	B7T0L1	Staphylococcus_virus	1.0e-285	98.8
WP_000339141.1\|1641438_1641741_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
WP_000466784.1\|1641876_1642176_-	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
1641960:1641977	attL	NA	NA	NA	NA
WP_000916020.1\|1642221_1642386_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166599.1\|1642378_1642768_-	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_020444680.1\|1642767_1644234_-\|plate	phage baseplate upper protein	A0A2I6PDE3	Staphylococcus_phage	3.1e-274	99.6
WP_000429552.1\|1644233_1646144_-	hypothetical protein	A0A2K9VBU3	Staphylococcus_phage	0.0e+00	100.0
WP_000179860.1\|1646159_1646450_-	hypothetical protein	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
WP_000384462.1\|1646449_1648033_-\|tail	phage tail protein	Q8SDP1	Staphylococcus_virus	7.1e-309	100.0
WP_020444679.1\|1648041_1648866_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	1.2e-158	99.6
WP_020444678.1\|1648865_1655066_-\|tail	phage tail tape measure protein	Q4ZCL0	Staphylococcus_virus	0.0e+00	99.7
WP_000438833.1\|1655079_1655238_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_000589166.1\|1655288_1655630_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.5e-54	100.0
WP_020444677.1\|1655687_1656143_-	Ig domain-containing protein	A0A2I6PER6	Staphylococcus_phage	9.7e-78	99.3
WP_000807540.1\|1656234_1656876_-\|tail	tail protein	A0A2I6PE59	Staphylococcus_phage	1.0e-120	100.0
WP_001023802.1\|1656910_1657306_-	DUF3168 domain-containing protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
WP_000110020.1\|1657306_1657708_-	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
WP_000395501.1\|1657704_1658037_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	6.2e-58	100.0
WP_000050975.1\|1658048_1658327_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PE36	Staphylococcus_phage	2.1e-46	100.0
WP_001142735.1\|1658395_1659559_-\|capsid	phage major capsid protein	A0A2I6PE62	Staphylococcus_phage	3.6e-217	100.0
WP_021187674.1\|1659570_1660344_-\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	5.1e-135	98.4
WP_020444675.1\|1660327_1661566_-\|portal	phage portal protein	A0A2I6PF26	Staphylococcus_phage	2.7e-231	98.1
WP_020444674.1\|1661570_1663262_-\|terminase	terminase large subunit	A0A2K9VBQ1	Staphylococcus_phage	0.0e+00	99.5
WP_020444673.1\|1663251_1663557_-\|terminase	P27 family phage terminase small subunit	U5U414	Staphylococcus_phage	8.3e-49	99.0
WP_000166257.1\|1663682_1664003_-	HNH endonuclease	A0A2K9VBV6	Staphylococcus_phage	4.6e-50	86.8
WP_000513704.1\|1664163_1664601_-	transcriptional regulator	A0A2K9VBV2	Staphylococcus_phage	6.1e-77	100.0
WP_078066180.1\|1664613_1665981_-	DEAD/DEAH box helicase	Q4ZCM9	Staphylococcus_virus	1.6e-261	99.1
WP_000665203.1\|1665961_1666252_-	VRR-NUC domain-containing protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
WP_011447017.1\|1666385_1666490_+	hypothetical protein	Q4ZCF8	Staphylococcus_virus	9.4e-13	100.0
WP_020444670.1\|1666592_1669040_-	virulence-associated E family protein	Q4ZCG0	Staphylococcus_virus	0.0e+00	99.3
WP_000265258.1\|1669091_1669292_-	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_000237866.1\|1669359_1669512_-	transcriptional activator RinB	A0A2I6PF16	Staphylococcus_phage	5.8e-19	98.0
WP_001125015.1\|1669514_1669715_-	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_000195789.1\|1669689_1669878_-	DUF1381 domain-containing protein	A0A2I6PF34	Staphylococcus_phage	2.3e-25	100.0
WP_001209219.1\|1669894_1670068_-	hypothetical protein	S4SVD5	Staphylococcus_phage	3.6e-25	100.0
WP_031782730.1\|1670631_1670880_-	DUF1024 family protein	A0A068A237	Staphylococcus_phage	2.7e-37	97.6
WP_001668981.1\|1670872_1671181_-	hypothetical protein	Q4ZBK6	Staphylococcus_phage	1.8e-51	100.0
WP_020444668.1\|1671520_1671925_-	hypothetical protein	A0A0E3T8H9	Staphylococcus_phage	2.5e-69	96.2
WP_072466103.1\|1671937_1672186_-	hypothetical protein	M9NTB1	Staphylococcus_phage	8.8e-41	98.8
WP_031782732.1\|1672185_1672440_-	DUF3310 domain-containing protein	A0A2I6PEN5	Staphylococcus_phage	2.4e-41	96.4
WP_031782733.1\|1672439_1672841_-	phage DNA polymerase	A0A2I6PF14	Staphylococcus_phage	3.6e-68	99.2
WP_001164629.1\|1672840_1673026_-	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_001796208.1\|1673038_1674991_-	DNA polymerase	A0A2I6PF18	Staphylococcus_phage	0.0e+00	100.0
WP_000645042.1\|1675059_1675617_-	DUF2815 family protein	A0A2I6PF05	Staphylococcus_phage	1.8e-97	100.0
WP_000762547.1\|1675642_1676809_-	DUF2800 domain-containing protein	A0A2D1G5B8	Staphylococcus_phage	8.3e-222	100.0
WP_000985984.1\|1676805_1677168_-	hypothetical protein	Q4ZCP8	Staphylococcus_virus	1.4e-55	99.2
WP_000175001.1\|1677182_1677506_-	hypothetical protein	A0A2I6PDL5	Staphylococcus_phage	1.7e-52	99.1
WP_001285954.1\|1677584_1677746_-	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_001124160.1\|1677758_1678022_-	helix-turn-helix domain-containing protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
WP_001097552.1\|1678046_1678262_-	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
WP_001128433.1\|1678316_1678682_+	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001025401.1\|1678650_1678896_-	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_000642492.1\|1678951_1679161_+	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
WP_000939498.1\|1679150_1679294_-	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_001148544.1\|1679322_1680099_-	Rha family transcriptional regulator	A0A2I6PD87	Staphylococcus_phage	1.1e-140	100.0
WP_001121027.1\|1680112_1680349_-	helix-turn-helix transcriptional regulator	A0A2I6PD81	Staphylococcus_phage	1.5e-37	100.0
WP_000333630.1\|1680500_1680815_+	helix-turn-helix transcriptional regulator	A0A0N9BAW4	Staphylococcus_phage	9.8e-53	100.0
WP_000525004.1\|1680827_1681289_+	hypothetical protein	A0A2K9VBR7	Staphylococcus_phage	1.2e-83	100.0
WP_000825948.1\|1681306_1681891_+	hypothetical protein	A0A2I6PD77	Staphylococcus_phage	1.4e-68	100.0
WP_001013104.1\|1682120_1682267_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.1e-14	89.6
WP_000191459.1\|1682263_1682878_-	hypothetical protein	A7TW88	Staphylococcus_phage	7.9e-107	100.0
WP_020444721.1\|1683003_1684209_+\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	1.7e-222	99.8
WP_001566047.1\|1684251_1686279_-	hypothetical protein	B5WZK7	Staphylococcus_phage	6.9e-115	97.7
WP_001548912.1\|1686271_1687201_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000987769.1\|1687445_1689197_-	two-component system sensor histidine kinase SrrB	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
1688420:1688437	attR	NA	NA	NA	NA
WP_000064078.1\|1689177_1689903_-	two-component system response regulator SrrA	W8CYM9	Bacillus_phage	3.5e-45	43.0

DBSCAN-SWA_11

1745027 : 1753339

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1745027_1745813_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924214.1\|1745938_1746829_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_020444722.1\|1746838_1748185_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	4.1e-55	33.7
WP_000683931.1\|1748298_1749399_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624584.1\|1749401_1750079_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1750209_1751316_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217261.1\|1751539_1753339_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0

DBSCAN-SWA_12

1823217 : 1832260

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1823217_1823736_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594993.1\|1823757_1826031_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
WP_000749795.1\|1826233_1828513_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1828787_1829048_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1829066_1830206_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019172.1\|1830228_1831254_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1831255_1832260_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_13

1971687 : 2046756

Staphylococcus_phage(94.74%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001549041.1\|1971687_1974105_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
WP_001025061.1\|1974392_1975574_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000764419.1\|1976633_1977197_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1977316_1977718_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1979296_1980124_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1980126_1980246_-	hypothetical protein	NA	NA	NA	NA
WP_052997228.1\|1980373_1981360_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.2e-182	99.7
WP_001008551.1\|1981481_1981946_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001838426.1\|1981978_1983139_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	4.1e-221	99.2
WP_000493892.1\|1983149_1983782_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_000077344.1\|1983788_1984832_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	6.3e-197	99.4
WP_020444739.1\|1985312_1986815_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000221179.1\|1987337_1987652_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_000989121.1\|1987651_1988944_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_000163235.1\|1988961_1989357_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
WP_001032833.1\|1989651_1990506_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1990781_1991006_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1991204_1991675_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1991787_1992231_+	competence protein ComK	NA	NA	NA	NA
WP_001030465.1\|1992217_1992661_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
WP_001168904.1\|1992956_1993592_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1994031_1994745_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1995004_1995307_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1995562_1995928_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623471.1\|1995924_1996278_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000453320.1\|1999097_1999931_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
WP_000366154.1\|2000142_2001051_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
WP_000933822.1\|2001175_2002369_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109906.1\|2002739_2004332_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_002868962.1\|2005326_2006073_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.1e-142	98.4
WP_000672014.1\|2006077_2006551_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_000718107.1\|2006616_2006874_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778523.1\|2006870_2007872_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
WP_000348360.1\|2007876_2009355_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
WP_011443643.1\|2009513_2009969_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.0e-79	98.6
WP_020444742.1\|2010270_2010921_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	1.0e-51	94.0
WP_000070653.1\|2011001_2011997_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
WP_000669046.1\|2012072_2012699_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.1e-79	82.7
WP_000627551.1\|2012739_2013084_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
WP_000414205.1\|2013181_2013733_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
WP_000494956.1\|2013950_2014592_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
WP_000809857.1\|2014705_2014891_-	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|2014892_2015069_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|2015079_2015463_-	hypothetical protein	NA	NA	NA	NA
WP_001549059.1\|2016066_2016210_-\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_001801861.1\|2016412_2016508_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791893.1\|2016630_2016732_+	hypothetical protein	NA	NA	NA	NA
WP_001037045.1\|2017079_2017457_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000195429.1\|2019406_2020579_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_041205415.1\|2024271_2025471_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.0e-227	99.5
WP_000028659.1\|2025463_2027020_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.3e-288	99.4
WP_001791797.1\|2027183_2027318_-	hypothetical protein	NA	NA	NA	NA
WP_001038688.1\|2027382_2028102_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
WP_001038759.1\|2028252_2028969_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
WP_011447030.1\|2029070_2029178_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|2029126_2029846_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038867.1\|2029966_2030686_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
WP_001039447.1\|2030743_2031466_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
WP_001039435.1\|2031590_2032298_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.6e-130	100.0
WP_001092763.1\|2033262_2033829_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_000586140.1\|2034302_2035001_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
WP_000581552.1\|2034997_2035759_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_001096791.1\|2035755_2036448_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000691541.1\|2036470_2037844_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_000504439.1\|2037853_2038372_-	flavoprotein	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_000566596.1\|2038387_2039632_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
WP_001803290.1\|2039624_2041367_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	2.5e-259	54.1
WP_000416756.1\|2041431_2041575_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
WP_000416759.1\|2042311_2042455_-	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_000782464.1\|2042695_2043679_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000473596.1\|2043680_2044616_-	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
WP_001790220.1\|2045415_2045955_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	2.0e-61	76.8
WP_000206350.1\|2045967_2046756_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8

DBSCAN-SWA_14

2127973 : 2226365

114

Staphylococcus_phage(88.16%)

portal,terminase,tail,protease,capsid,holin,transposase,head,tRNA,integrase

attL 2192169:2192186|attR 2216287:2216304

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000545370.1\|2127973_2129401_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_000027928.1\|2129413_2130871_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|2130872_2131175_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957015.1\|2131541_2133080_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831698.1\|2133168_2134368_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774565.1\|2134380_2136384_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
WP_000992921.1\|2136387_2138580_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272068.1\|2138576_2139269_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|2139440_2139743_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|2139851_2141147_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827748.1\|2142007_2143174_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434933.1\|2143204_2143531_+	staphostatin A	NA	NA	NA	NA
WP_000669862.1\|2143822_2143996_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2143976_2144579_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040873.1\|2144849_2145671_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.8e-69	52.7
WP_000284431.1\|2145663_2147133_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.5e-108	45.1
WP_020444756.1\|2147316_2148393_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177817.1\|2148412_2149207_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2149278_2149386_+	hypothetical protein	NA	NA	NA	NA
WP_000323161.1\|2149396_2150959_-	SLC13 family permease	NA	NA	NA	NA
WP_000275730.1\|2151163_2152261_-	pectate lyase	U5PWM6	Bacillus_phage	1.9e-47	34.6
WP_000149686.1\|2152632_2153193_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2153245_2154175_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|2154369_2154543_-	hypothetical protein	NA	NA	NA	NA
WP_001021214.1\|2154594_2155974_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181322.1\|2156093_2157122_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2157391_2157793_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2158365_2158539_-	hypothetical protein	NA	NA	NA	NA
WP_001188077.1\|2158989_2160030_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713060.1\|2160086_2160929_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2160925_2161483_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2161542_2162067_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2162187_2162751_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221651.1\|2162816_2163557_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|2163556_2164429_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645727.1\|2164425_2165106_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991302.1\|2165106_2166003_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|2165999_2166380_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|2166643_2166820_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2167062_2167161_-	hypothetical protein	NA	NA	NA	NA
WP_001068542.1\|2167360_2168647_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_001549158.1\|2169271_2171026_-	extracellular adherence protein Eap/Map	NA	NA	NA	NA
WP_000669789.1\|2171983_2172163_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001791826.1\|2172473_2172734_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702262.1\|2172786_2173137_-	complement inhibitor SCIN-A	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
WP_000195429.1\|2173200_2174373_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000727651.1\|2175151_2175601_+	chemotaxis-inhibiting protein CHIPS	A0A1P8L6A8	Staphylococcus_phage	2.1e-77	99.3
WP_000919350.1\|2176680_2177172_-	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
WP_000861038.1\|2177362_2178118_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000611512.1\|2178129_2178384_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_078156886.1\|2178595_2178772_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	5.5e-21	94.8
WP_000539688.1\|2178921_2179218_-	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_001040261.1\|2179275_2179563_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_001153681.1\|2179609_2179762_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_000582158.1\|2179751_2183537_-	hypothetical protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.4
WP_000567408.1\|2183552_2185037_-\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
WP_001795393.1\|2185033_2189563_-\|tail	phage tail tape measure protein	A0A1X9H084	Staphylococcus_phage	0.0e+00	100.0
WP_001789580.1\|2189619_2189781_-	hypothetical protein	A0A0H3U330	Staphylococcus_phage	1.6e-22	100.0
WP_001096355.1\|2189807_2190158_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_072050172.1\|2190207_2190432_-	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	8.8e-32	98.6
WP_000268741.1\|2190473_2191118_-\|tail	phage tail protein	W5R9H4	Staphylococcus_phage	6.5e-120	100.0
WP_000565498.1\|2191118_2191526_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114225.1\|2191522_2191927_-	HK97 gp10 family phage protein	A0A2I6PDJ6	Staphylococcus_phage	4.3e-69	100.0
WP_000755150.1\|2191923_2192286_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
2192169:2192186	attL	NA	NA	NA	NA
WP_000150936.1\|2192269_2192554_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1\|2192543_2192828_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154555.1\|2192847_2193993_-\|capsid	phage major capsid protein	A0A1X9H072	Staphylococcus_phage	5.6e-215	100.0
WP_000025274.1\|2194737_2195925_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000625088.1\|2195940_2197602_-\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|2197598_2197943_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988336.1\|2198073_2198373_-	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
WP_000590126.1\|2198604_2199021_-	hypothetical protein	A0A1X9H0U8	Staphylococcus_phage	2.9e-76	100.0
WP_000265039.1\|2199048_2199249_-	DUF1514 family protein	R9QT57	Staphylococcus_phage	1.4e-28	98.5
WP_000595265.1\|2199248_2199398_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000195820.1\|2199394_2199601_-	DUF1381 domain-containing protein	A0A1X9H0C2	Staphylococcus_phage	1.3e-21	100.0
WP_001066444.1\|2199637_2200174_-	dUTP diphosphatase	A0A1X9H0S5	Staphylococcus_phage	1.4e-96	100.0
WP_000197967.1\|2200166_2200577_-	hypothetical protein	C8CH13	Staphylococcus_phage	2.3e-70	100.0
WP_031868690.1\|2200573_2201107_-	hypothetical protein	A0A1X9H0D4	Staphylococcus_phage	8.5e-81	96.1
WP_000979209.1\|2201103_2201451_-	hypothetical protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
WP_072466103.1\|2201861_2202110_-	hypothetical protein	M9NTB1	Staphylococcus_phage	8.8e-41	98.8
WP_000022727.1\|2202109_2202364_-	DUF3310 domain-containing protein	A0A2I6PEN5	Staphylococcus_phage	1.6e-42	100.0
WP_001187239.1\|2202727_2202913_-	DUF3113 family protein	Q4ZAR6	Staphylococcus_virus	2.4e-27	100.0
WP_020444760.1\|2202917_2203322_-	DUF1064 domain-containing protein	G4KNP2	Staphylococcus_phage	8.1e-68	98.5
WP_041205435.1\|2203331_2203553_-	DUF3269 family protein	Q9G021	Staphylococcus_phage	6.4e-35	98.6
WP_000237153.1\|2203565_2203727_-	hypothetical protein	D2JGK6	Staphylococcus_phage	4.5e-22	100.0
WP_016028252.1\|2205317_2205977_+	hypothetical protein	E0Y3Q0	Staphylococcus_virus	1.4e-120	100.0
WP_020444663.1\|2206086_2206761_-	hypothetical protein	A0A1X9H0A9	Staphylococcus_phage	3.8e-126	97.3
WP_041205441.1\|2206774_2207203_-	single-stranded DNA-binding protein	A0A0E3XC62	Staphylococcus_phage	4.4e-64	90.8
WP_000139720.1\|2207202_2207826_-	DUF1071 domain-containing protein	A0A2H4PQQ6	Staphylococcus_phage	1.4e-114	100.0
WP_000815401.1\|2207818_2208040_-	DUF2483 family protein	A7TWM6	Staphylococcus_phage	3.2e-34	100.0
WP_000291489.1\|2208049_2208310_-	DUF1108 family protein	A0A1W6JQ03	Staphylococcus_phage	7.6e-43	100.0
WP_000066020.1\|2208402_2208564_-	DUF1270 domain-containing protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
WP_001120197.1\|2208560_2208881_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
WP_000275058.1\|2208939_2209572_+	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
WP_000939496.1\|2209586_2209727_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
WP_001148861.1\|2209757_2209955_-	hypothetical protein	A0A1W6JPV3	Staphylococcus_phage	1.2e-24	100.0
WP_001148337.1\|2209970_2210720_-	phage antirepressor KilAC domain-containing protein	Q8SDM9	Staphylococcus_phage	4.4e-136	99.6
WP_000351243.1\|2210776_2211316_+	hypothetical protein	A7TW92	Staphylococcus_phage	1.7e-97	100.0
WP_000435341.1\|2211339_2211600_-	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_000338186.1\|2211617_2211842_-	DUF739 family protein	A7TW90	Staphylococcus_phage	4.5e-36	100.0
WP_001208482.1\|2212000_2212771_+	helix-turn-helix domain-containing protein	A0A1P8L6G7	Staphylococcus_phage	6.2e-141	100.0
WP_000705240.1\|2212970_2213153_+	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
WP_001013104.1\|2213188_2213335_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.1e-14	89.6
WP_000191459.1\|2213331_2213946_-	hypothetical protein	A7TW88	Staphylococcus_phage	7.9e-107	100.0
WP_000857193.1\|2214053_2215091_+\|integrase	site-specific integrase	E9LT82	Staphylococcus_phage	1.0e-178	93.0
WP_000595324.1\|2216209_2217226_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	1.1e-25	29.0
2216287:2216304	attR	NA	NA	NA	NA
WP_000791407.1\|2217247_2218303_-	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3
WP_000206638.1\|2218737_2219961_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_000812008.1\|2220332_2221178_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000825510.1\|2221239_2222151_-	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001045079.1\|2222311_2223619_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000022887.1\|2224471_2224915_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001797573.1\|2225079_2225457_-	hypothetical protein	NA	NA	NA	NA
WP_020444766.1\|2225774_2226365_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	4.2e-97	95.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012018

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection