CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014159	Aerococcus christensenii strain CCUG28831 chromosome, complete genome	1 crisprs	cas3,DEDDh,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	0	11	7	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014159_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014159_1

1317504-1318450

TypeI-E

I-C,I-E,II-B

Consensus_repeat	Method
CTTTTTCCCGCGTATGCGGGGGTGATCC	PILER-CR
CTTTTTCCCGCGTATGCGGGGGTGATCC	CRISPRCasFinder
CTTTTTCCCGCGTATGCGGGGGTGATCCT	CRT

15 spacers

DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP014159_1

>merge|NZ_CP014159|1|1317504-1318450|PILER-CR,CRISPRCasFinder,CRT
CTTTTTCCCGCGTATGCGGGGGTGATCCTAAGGAGGGCGCTTATTTCATCAAAGCTTGTGTCTTTTTCCCGCGTATGCGGGGGTGATCCTAAGCCTCACCGTCAACGACAAAAACCCCAATTTCTTTTTCCCGCGTATGCGGGGGTGATCCTGGGTAGCCAACCAAGTATACAAGCGTGGGGATCTTTTTCCCGCGTATGCGGGGGTGATCCTAAGCCGAATAACCATGTATTTGACCGCCACTGCTTTTTCCCGCGTATGCGGGGGTGATCCCAGCAACACCAGATCGGACAGCCACTTATTATGCTTTTTCCCGCGTATGCGGGGGTGATCCTATTTATTCTCTTCCATAAATTTTGAAATATCTCTTTTTCCCGCGTATGCGGGGGTGATCCTTGGTTATTAGAGAAAGCAGATTCCCCGATACTCTTTTTCCCGCGTATGCGGGGGTGATCCTATTTTTCTATTTAGTCTTAGTCGATCAGTTGCCTTTTTCCCGCGTATGCGGGGGTGATCCCAGATCATACTTTTATGGTGATGAAGCGATTTGCTTTTTCCCGCGTATGCGGGGGTGATCCTGCGATGTCTCAAGTGGCAAATGATGTTTCAAGCTTTTTCCCGCGTATGCGGGGGTGATCCTGGTAGCAAGCGGTTTTTTCAAAGCGAAGATTTCTTTTTCCCGCGTATGCGGGGGTGATCCTGCCGCTGAAAGTGCTGGTAGTCGGATAAGTGGCTTTTTCCCGCGTATGCGGGGGTGATCCCAACATCTCTCCTTACATGCTGGCTGGCATATCCCTTTTTCCCGCGTATGCGGGGGTGATCCTGGCTAAGAATAATCAAAACAAACAAATGACCGCTTTTTCCCGCGTATGCGGGGGTGATCCTTTAAAAGGTGCCAATTTAGAAGATGCCGATTTACTTTTTCCCGCATATGCGGGGGTAATTTA

>NZ_CP014159|1|1|1317504-1318387|PILER-CR
CTTTTTCCCGCGTATGCGGGGGTGATCC	TAAGGAGGGCGCTTATTTCATCAAAGCTTGTGT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TAAGCCTCACCGTCAACGACAAAAACCCCAATTT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGGGTAGCCAACCAAGTATACAAGCGTGGGGAT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TAAGCCGAATAACCATGTATTTGACCGCCACTG
CTTTTTCCCGCGTATGCGGGGGTGATCC	CAGCAACACCAGATCGGACAGCCACTTATTATG
CTTTTTCCCGCGTATGCGGGGGTGATCC	TATTTATTCTCTTCCATAAATTTTGAAATATCT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TTGGTTATTAGAGAAAGCAGATTCCCCGATACT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TATTTTTCTATTTAGTCTTAGTCGATCAGTTGC
CTTTTTCCCGCGTATGCGGGGGTGATCC	CAGATCATACTTTTATGGTGATGAAGCGATTTG
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGCGATGTCTCAAGTGGCAAATGATGTTTCAAG
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGGTAGCAAGCGGTTTTTTCAAAGCGAAGATTT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGCCGCTGAAAGTGCTGGTAGTCGGATAAGTGG
CTTTTTCCCGCGTATGCGGGGGTGATCC	CAACATCTCTCCTTACATGCTGGCTGGCATATCC
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGGCTAAGAATAATCAAAACAAACAAATGACCG
CTTTTTCCCGCGTATGCGGGGGTGATCC

>NZ_CP014159|1|1|1317504-1318449|CRISPRCasFinder
CTTTTTCCCGCGTATGCGGGGGTGATCC	TAAGGAGGGCGCTTATTTCATCAAAGCTTGTGT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TAAGCCTCACCGTCAACGACAAAAACCCCAATTT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGGGTAGCCAACCAAGTATACAAGCGTGGGGAT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TAAGCCGAATAACCATGTATTTGACCGCCACTG
CTTTTTCCCGCGTATGCGGGGGTGATCC	CAGCAACACCAGATCGGACAGCCACTTATTATG
CTTTTTCCCGCGTATGCGGGGGTGATCC	TATTTATTCTCTTCCATAAATTTTGAAATATCT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TTGGTTATTAGAGAAAGCAGATTCCCCGATACT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TATTTTTCTATTTAGTCTTAGTCGATCAGTTGC
CTTTTTCCCGCGTATGCGGGGGTGATCC	CAGATCATACTTTTATGGTGATGAAGCGATTTG
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGCGATGTCTCAAGTGGCAAATGATGTTTCAAG
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGGTAGCAAGCGGTTTTTTCAAAGCGAAGATTT
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGCCGCTGAAAGTGCTGGTAGTCGGATAAGTGG
CTTTTTCCCGCGTATGCGGGGGTGATCC	CAACATCTCTCCTTACATGCTGGCTGGCATATCC
CTTTTTCCCGCGTATGCGGGGGTGATCC	TGGCTAAGAATAATCAAAACAAACAAATGACCG
CTTTTTCCCGCGTATGCGGGGGTGATCC	TTTAAAAGGTGCCAATTTAGAAGATGCCGATTTA
CTTTTTCCCGCATATGCGGGGGTAATTT

>NZ_CP014159|1|1|1317504-1318450|CRT
CTTTTTCCCGCGTATGCGGGGGTGATCCT	AAGGAGGGCGCTTATTTCATCAAAGCTTGTGT
CTTTTTCCCGCGTATGCGGGGGTGATCCT	AAGCCTCACCGTCAACGACAAAAACCCCAATTT
CTTTTTCCCGCGTATGCGGGGGTGATCCT	GGGTAGCCAACCAAGTATACAAGCGTGGGGAT
CTTTTTCCCGCGTATGCGGGGGTGATCCT	AAGCCGAATAACCATGTATTTGACCGCCACTG
CTTTTTCCCGCGTATGCGGGGGTGATCCC	AGCAACACCAGATCGGACAGCCACTTATTATG
CTTTTTCCCGCGTATGCGGGGGTGATCCT	ATTTATTCTCTTCCATAAATTTTGAAATATCT
CTTTTTCCCGCGTATGCGGGGGTGATCCT	TGGTTATTAGAGAAAGCAGATTCCCCGATACT
CTTTTTCCCGCGTATGCGGGGGTGATCCT	ATTTTTCTATTTAGTCTTAGTCGATCAGTTGC
CTTTTTCCCGCGTATGCGGGGGTGATCCC	AGATCATACTTTTATGGTGATGAAGCGATTTG
CTTTTTCCCGCGTATGCGGGGGTGATCCT	GCGATGTCTCAAGTGGCAAATGATGTTTCAAG
CTTTTTCCCGCGTATGCGGGGGTGATCCT	GGTAGCAAGCGGTTTTTTCAAAGCGAAGATTT
CTTTTTCCCGCGTATGCGGGGGTGATCCT	GCCGCTGAAAGTGCTGGTAGTCGGATAAGTGG
CTTTTTCCCGCGTATGCGGGGGTGATCCC	AACATCTCTCCTTACATGCTGGCTGGCATATCC
CTTTTTCCCGCGTATGCGGGGGTGATCCT	GGCTAAGAATAATCAAAACAAACAAATGACCG
CTTTTTCCCGCGTATGCGGGGGTGATCCT	TTAAAAGGTGCCAATTTAGAAGATGCCGATTTA
CTTTTTCCCGCATATGCGGGGGTAATTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014159.1\|WP_060777145.1\|1307297_1307531_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014159.1\|WP_060777159.1\|1324565_1324943_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|374224
NZ_CP014159.1\|WP_144428637.1\|1314246_1314981_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP014159.1\|WP_082632735.1\|1322343_1323573_+\|minor-capsid-protein	unknown	unknown	gnl\|CDD\|213641
NZ_CP014159.1\|WP_060777149.1\|1313124_1314240_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP014159.1\|WP_060777163.1\|1330421_1332575_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NZ_CP014159.1\|WP_060777161.1\|1326114_1326855_+\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|187594
NZ_CP014159.1\|WP_060777153.1\|1316580_1317483_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NZ_CP014159.1\|WP_060777148.1\|1312541_1313135_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP014159.1\|WP_144428660.1\|1323614_1323854_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014159.1\|WP_082632731.1\|1325421_1325643_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|238038
NZ_CP014159.1\|WP_060777146.1\|1308031_1310797_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP014159.1\|WP_060777144.1\|1305917_1307288_+\|aspartate-kinase	unknown	unknown	gnl\|CDD\|236364
NZ_CP014159.1\|WP_060777151.1\|1315001_1315640_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_CP014159.1\|WP_082632730.1\|1320932_1322360_+\|phage-portal-protein	unknown	unknown	gnl\|CDD\|377466
NZ_CP014159.1\|WP_060777162.1\|1327355_1330070_-\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319781
NZ_CP014159.1\|WP_156407349.1\|1323911_1324067_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014159.1\|WP_144428638.1\|1315639_1316578_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP014159.1\|WP_062121880.1\|1310802_1312533_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP014159.1\|WP_060777160.1\|1324999_1325194_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942

Protein	Function_ID	Function_description	E-value
NZ_CP014159.1\|WP_060777160.1\|1324999_1325194_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	8.45494e-16
NZ_CP014159.1\|WP_060777159.1\|1324565_1324943_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	4.95597e-14
NZ_CP014159.1\|WP_144428637.1\|1314246_1314981_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.88375e-41
NZ_CP014159.1\|WP_082632735.1\|1322343_1323573_+\|minor-capsid-protein	gnl\|CDD\|213641	TIGR01641, Uncharacterized_protein_MJ0329, phage putative head morphogenesis protein, SPP1 gp7 family. This model describes a region of about 110 amino acids found exclusively in phage-related proteins, internally or toward the C-terminus. One member, gp7 of phage SPP1, appears involved in head morphogenesis. [Mobile and extrachromosomal element functions, Prophage functions].	1.43612e-21
NZ_CP014159.1\|WP_060777149.1\|1313124_1314240_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	6.0525e-149
NZ_CP014159.1\|WP_060777163.1\|1330421_1332575_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NZ_CP014159.1\|WP_060777161.1\|1326114_1326855_+\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.10589e-101
NZ_CP014159.1\|WP_060777153.1\|1316580_1317483_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	2.43488e-43
NZ_CP014159.1\|WP_060777148.1\|1312541_1313135_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.56771e-41
NZ_CP014159.1\|WP_060777146.1\|1308031_1310797_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	8.26818e-85
NZ_CP014159.1\|WP_060777144.1\|1305917_1307288_+\|aspartate-kinase	gnl\|CDD\|236364	PRK09034, PRK09034, aspartate kinase; Reviewed.	0
NZ_CP014159.1\|WP_060777151.1\|1315001_1315640_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	5.91137e-66
NZ_CP014159.1\|WP_082632730.1\|1320932_1322360_+\|phage-portal-protein	gnl\|CDD\|377466	pfam05133, Phage_prot_Gp6, Phage portal protein, SPP1 Gp6-like. This protein forms a hole, or portal, that enables DNA passage during packaging and ejection. It also forms the junction between the phage head (capsid) and the tail proteins. During SPP1 morphogenesis, Gp6 participates in the procapsid assembly reaction. This family also includes the old Pfam family Phage_min_cap (PF05126).	2.4946e-84
NZ_CP014159.1\|WP_060777162.1\|1327355_1330070_-\|cation-translocating-P-type-ATPase	gnl\|CDD\|319781	cd02089, P-type_ATPase_Ca_prok, prokaryotic P-type Ca(2+)-ATPase similar to Synechococcus elongatus sp. strain PCC 7942 PacL and Listeria monocytogenes LMCA1. Ca(2+) transport ATPase is a plasma membrane protein which pumps Ca(2+) ion out of the cytoplasm. This prokaryotic subfamily includes the Ca(2+)-ATPase Synechococcus elongatus PacL, Listeria monocytogenes Ca(2+)-ATPase 1 (LMCA1) which has a low Ca(2+) affinity and a high pH optimum (pH about 9) and may remove Ca(2+) from the microorganism in environmental conditions when e.g. stressed by high Ca(2+) and alkaline pH, and the Bacillus subtilis putative P-type Ca(2+)-transport ATPase encoded by the yloB gene, which is expressed during sporulation. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP014159.1\|WP_144428638.1\|1315639_1316578_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	5.41385e-126
NZ_CP014159.1\|WP_062121880.1\|1310802_1312533_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	2.28971e-78
NZ_CP014159.1\|WP_082632731.1\|1325421_1325643_+\|HNH-endonuclease	gnl\|CDD\|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	5.58471e-06

>NZ_CP014159.1|WP_060777153.1|1316580_1317483_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MPFTVITLKKVSAYLRGDLTKWMQEIAPGVYVGNFNTKIREKIWQRVKENVSSGEATMSYAFRNEIGYNFKTLNTNRQVIDYEGIPLVRVNDQTQASHMNLGFSSAYKMRQARKFQAHKSSKVAKLHSAYVVLDIETDGLQFEVNQIIELGAVKEKNGVRTSFNQLINHDRELPSHIKELTGITEEMLRKEGVNLEEALKKLFEFIGDLPIIGYNINFDINFINYNLIQLNHNPLHNKTYDVMSYVKREKLFLKNYKLETVLASYNIEDRVPHRALKDAELIDKLINEVNKLRDLFGNQG
>NZ_CP014159.1|WP_144428638.1|1315639_1316578_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MMDKAGAKKTELNELPRISDRVSFIYLEHAKINRQDSAIAVRDQQGLICIPCSMIGVLLLGPGTDISHRAIELIGDTGTTIVWVGERGVRFYAQGRPLAHTTRLLEAQAKLVSNTKTRVMVARKMYQMRFGDEDVSKLTMQQLRGREGARVRKIYRKQSKRHHVEWNGRHYDIEDFLEGSVIDQALSAANVSLYGVVHSVIAALGMSAGLGFVHTGHDKSFVYDIADLYKAELTIPLAFQVAAECNEDDDIGKITRLKMRDALVDGKLLKRIVQDLQYLMGITDEIIEGDVLHLWDDKDGLIKHGVNYERMD
>NZ_CP014159.1|WP_060777151.1|1315001_1315640_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRVEIDRNNRQKIKDLTHLGAYHNWVEQSFPDELKQEIRTRKLWRVDRLDGKDYLLIVSSSIPDLKGLERYGVEGSAASKNYDRFLDSLRNGQVMRFRVVLNPVVAKLETPSSKRGRLLPLLSEADQLNFFMKRTHSNGFSVEANDVMLVETGFEVLKKSHQRAVRLKKASYEGKLTISDVEVFRNTLIKGMGRKKAYGFGMMTVIPGV
>NZ_CP014159.1|WP_144428637.1|1314246_1314981_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRLMKTILLKFAVPLQSYGTDSHFDNRKTDFYPSKSSVIGLISACLGYRRYQTEQIQALNALNFAVRVDQAGMLLRDFQTVKKLKNNGTVESAYVTNRYYLQDAVFVVGISHPDDQMMEQIYYAFNHPYFQPFLGRRSAPLNADFLLAIEEGDMIEVFKQLPWQAAVWYQKKVMKSKSKIRLDAYFDKGVVSDGEVGSIRNDYVESFDVNDRKFKQRVEVKINLEVKPTYVPKVSSTHDVFSWL
>NZ_CP014159.1|WP_060777149.1|1313124_1314240_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MNNNQRLFLDIHAIQVVPPSNINRDDTGSPKTALYGGVRRARVSSQSWKHAMRRYFNENGSKENVGVRTLDIVEYVAQSILSLNNHLTKEEALNMADDVLNKAGIKTELPKKTDKETAVKRAKALTFLGSKQAQALAKSALDGVNDKKVLQDILTDNPAIDIALFGRMVADDASLNEDASCQVAHAISTHAVQTEFDYFTAIDDLSPEEKAEAKMLGTIEYNSSTLYRYANIALHEFVKQLDDQSATIEAVKLFIKAFVLSMPTGKMNTFANATLPQLVLVSLRHDRPVNLVTAFEQPVRTDGHNGYAKSSCQKLFDEGQKIAKFTEKADFTAFVAMEEMDQVNTFGQEEVNLQSLLDELGLQLNERLAHD
>NZ_CP014159.1|WP_060777148.1|1312541_1313135_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MDEKNNKATVYSVTQKVLFKLEQSLETSHGKAMLAKLRHSVGKSIGESVEIWPLLFSEFPETFLSKDGQATKEELAIITALQFYALHQQGKSGSVNFKASHAYENLGCSLSALRNNEDNTAVDRRFNVLITSTTIEEFIYHLRQMITLLKSKAKTTKIDYAKLAEDIFYFQLGYAENVRLRWGQEYYRYKGEENHEQ
>NZ_CP014159.1|WP_062121880.1|1310802_1312533_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSRFNLIDEPWIAVTVDGRGSSRLVSLNDLFSHAEEYVDLAGDSRPQDFAILRMLLAILQTHFSRVDESGRVYEELEVNNDQQVISDLDEDDKDDYLDNLYETWQIIWQSGRFPTTILDYLSHWHDRFYLFDDKYPFYQVTKDVISEEKLNNKSATSISGKNINRLVSESENKLSLFSPKTTNYKAKLTEAEVARWLLTYQGYTGVADKASFGKEKYKKVSKGWLFDLGGIYLKGHNLFETLWLNCALKHPNKKYQGNSAHPCWEVDSQSLIDKYLEFNSKGERGKVVTDLADLYTNWSRAIYMDPLIDLSQDFMFEVVKLPEIEHQDNFLELMTLWRKNKKDPNKGYSTPRKHLPDQALWRSFGILTGSYQKLDEPNSNYHPCPGIIAWMCEIQEDIDKAKIILQATSMKYDNNPCSRNPVDEICDQLVLNEQLLTDNEGWSVYITNCVEKTNRIITGTYRNFLLDIKTIRGQNSNAWIDQELEQIYFLVDRSFKVWIREIDPEKDSREEKAKIWFDSLQKLLNDQVKRFVENATYRDCLGIKPKDNKNKKGDKVLNVFIAYNKFNYWLKQNLGK
>NZ_CP014159.1|WP_060777146.1|1308031_1310797_+|CRISPR-associated-helicase/endonuclease-Cas3
MEAVKAAWAKKRIDSSGQFKWLSLYDHLRDTRGIAGLIWEHWLSSGQKDYLLKNSQADDEDQIKRLYLFLAGIHDLGKLLPAFLIQEGYNSSADLKNLLLDKLEAVGFSGISELKLQFRGKTPHALAGQYLLQSYEKNGIDEGLASIIGAHHGRPAEVANEVAAQKHYVANYFQTEDENSPLYQKWTQAREEVIQWVLKETEFESLKTLPTLTQPGQVLMSGLVIMADWIASNEDYFPLLSVDQEEVLDEGKRIINGFQKWYKTQPWCPSLIESSNLFWKRFHFDSPNMIQSKLAELVNTSLDPGIFILEAPMGIGKTEAALLASELLAAKKGVGGIFFGLPTQATSNGIFPRIESWLESIVKDSEYTLGLRLLHGKASLNKDFDHLKQEALVYEEGAKVTVNEWFEGRKKAILDDFVVGTIDQFLLASLKQKHLALRHLGLSKKVLILDEIHACDAYMSVYLKRALRWMGAYDVPVILLSATLQSSRREAFIKSYLNGKKGASKQKITMDLPQKDVYPLITYSDGLCAKQFSNFELKESKKVIVKKIAEEDFIEIVIQLIKNEGVVGLIVNTVKRAQELGEIFQEKLGEDKVEVFHSRFIASQRIKKEDQLLQLIGKKAKRPKHKLIIGTQVIEQSLDINFDVLISDLAPMDSLLQRVGRLHRHDIEYPKAYQQAVLYVVGIDSEFKFSDSSEKVYGDYLLAKTQLALPDQLQLPQDISPLIQKVYSGLSENEQKNDLLRSLKQKYDKEIKDKDSKAQQYLLNKPIYQCKRDLSNTLIGLIKNEDSSQEEGTEFQREIKACAQVRDSLPTIEVIALKKIGTGYGLFGSSEDLSNQIDNNQVAKIIAQQTLNLPSFFAKGRLADTIIKELEEYRCQYLTNWKDQVWLKSSLALVFDEENHYQLGNYKLTYDWNLGLMWERM
>NZ_CP014159.1|WP_060777145.1|1307297_1307531_+|hypothetical-protein
MSYKKLSLLFPLVLFTLAACGQHKQSAAEESKAPVTQPVVEDNGKKSTQEHSPSKKEKKEKTPAKPSKNMHKKTKKN
>NZ_CP014159.1|WP_060777144.1|1305917_1307288_+|aspartate-kinase
MKVVKFGGSSLANARQLEKVKNIMASDPTRRIAVVSAPGKRFDSDTKVTDLLIELASQCLNGSADTLQTFKEIIERYASIAEELSIEEPIIEEITRSLSELLDMDKSVPGYFIDAVKASGEDNNAKLIAAYFRKAGLKARYINPKEAGLILSDEPGQAKVLAESYLNLYALRNYEEILVFPGFFGYTRKGRLVTFSRGGSDITGAIVANGVEAAMYENFTDVDNIFVANPKIVQNPVGISHLTYREMRELSYAGFSVLHDEALYPAFAEGIPVVVKNTNNPSAPGTVICEERPEGSDPFAITGIASQKGFASIYISKYMMNREVGFVRRVLSVFESFNLSIEHVVSGIDDIDVIFKEDQLSGNEIEHLLSEIKHQTAADQVVKCDNLCLLMVVGESMKSQVGITAKIASALSKASINLEMINQGSSENSLMFGIKEDQEEYAVRAVYNAFFQEDPR
>NZ_CP014159.1|WP_082632730.1|1320932_1322360_+|phage-portal-protein
MVCFLEINKNRKVKNVDDLLSSYGKLCRLSGISQQKIVATFSAEPFAPSADNRIASDFAHYITIFEQGYMLGRPIQYKNEDTTLQEQINLFVEENNEAAHNVLIKTDLSIYGRAYELLTVERYDESSPITVKLTKLAPEQTFVVYDDSYHDQSLFGVNYYTIDYGEGYRKSYIVVYTKDAVYRYADDSRDKNSSMHFVSSEEHFLKGEPINEYKNNEDRTGSYEAVLDTIDAYDLSQSELANFQQDSVDAILVISGNPYTGADEKDFLEDGRINPNGRLGISLAFRESKMIILDDNPNPDGVKPDAKYLVKAYDSKGAEDYKKRLVGDILRFTFTPDTSDEHFGSNQSGESMKYKLMASDNLRAQQERLFKQGLMRRLRLAANIWSIKGNEATAYRQISQTSVIFTPNVPKSGKEVIEMAKDLYNVVSDTTVYEILNSVTGVSPEDELKRIKAESEDSETETAEGAGGEEDGEEV
>NZ_CP014159.1|WP_082632735.1|1322343_1323573_+|minor-capsid-protein
MVKKSSYWKNRTKELMQYAEQQDKVMFQELAKLYGETFKDVQKEIFAFYAKYAENNKITIQEAKQRLRRTDLSDYRENARRYREEAKTPELLERLNEQYVSSKATRLDALKLDLTYQLGLLQGKVSGSFDSYLKKLAKHSYRKISGGLSDSTLNEPALEQLVKTPFEGYNYSQQVWGNVDHLARDLHKTLTRGFVKGFSPHEMATEIRKRHDVAKHRAETLVRTDGSMVINNATLKRYKDVGLKFYRIHVHIDSRTSDICMNISKLDKAYKLSEAQPGYNMPPLHPNCRSTIVPDDEDMDRADERDIEFVRNYDKIGLEERFDYVMNGEELFIPKGAEITNVKVIAGKGSGTELRVKHKLVNQYGGNPNDWQKAVGKIESAKYMFDMHWYRKNDTEQTEIKLKIRRDQK
>NZ_CP014159.1|WP_144428660.1|1323614_1323854_+|hypothetical-protein
MEVIGRVRYNGESFGIDSLTNDEIYDVINVDRGDMLRVVDDSKEDYLYSLKNPRPIDGSSPGGKWELVEDFTGELSKFL
>NZ_CP014159.1|WP_156407349.1|1323911_1324067_+|hypothetical-protein
MKDRETYNETRAISNYEKMLLWAIENDVKKEDFVVAGKIFFSGVWGPKVVE
>NZ_CP014159.1|WP_060777159.1|1324565_1324943_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLIYPATFEKGEKYIIVKFPDIPAAMTQGDSYEQAYEMASEVLGAVLEDYETYPEPSSIKDIQSEFPNKEVALIGFDPVAYRRKYHSKTIRKNVTVPEWLNDLANIENINFSQTLTEALKEKLGV
>NZ_CP014159.1|WP_060777160.1|1324999_1325194_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MPITPKKLVKILQKNGFKELRQRGSHKVMYNENTNRTTVVPMHNKDIDDSFYKDILKQAGLKWS
>NZ_CP014159.1|WP_082632731.1|1325421_1325643_+|HNH-endonuclease
MANLRADRQGAHRTQFERNRKRILKTQNVCGICGKPVDVSLKQGNPMSPVIDHIIPVAKGGHPSDIGNLQLVI
>NZ_CP014159.1|WP_060777161.1|1326114_1326855_+|3-oxoacyl-ACP-reductase-FabG
MFSFSDQVVVVTGAGQGIGAEVAKEFAQADGKVVIIDFNGETAEATAQEIKANGGEDLAYQADFSDYERAQEIIADVVEKWGKVDVLINNAGITRDRSFKKISKKEWDQVIATNLTGTFNYSQACFNNMVENGYGRIASSSLAGVEENFGQVNYSASKGGIMAMTKTMAREGAAKGTTANCVAPGFVETPMTAAIPEDVKQGMINSIPVKRIGYPKDIAYAYMFLAAKESGYITGQTLQVNGGVNM
>NZ_CP014159.1|WP_060777162.1|1327355_1330070_-|cation-translocating-P-type-ATPase
MTEKNSFFTESVEAIASQLHTDPLSGLTSEEAQRRLAQNGPNEIQEGEQTTLWQKFIDQFKDAMIVILLISAALSILLEGIHGLVDASIILVVVLLNAILGVLQETKAEDAIASLKDMSSPKAHVIRDGESVIIDSRQIVVGDVVVLEAGNVVPADLRLTSVHSLKIEEAALTGESVPVEKNLEKVNSDASLGDRRNMAFSSTNVTYGRGQGIVVATAMSTEVGHIATMIQNSEEKITPLKANMNQLTKFLTWAIVVIAAIIFFIGLFTGLYSWIEMLLVAISIAVAALPEGLPAISTIILALGTQKMADRNALVRKLPAVETLGGTEVICSDKTGTLTQNKMTIEKIFYNGHFHEVSEEVDFSEPLFQVMLLDNDSTLTADLTLTGDPTETAMIQLAIDKGYDVKGLREGTPRLGEIPFDSERKMSTTVHQNKNASSFGNSPYVILTKGAPDVLINNCTSYFENGEIHPMTEDYRQMLLDQNDQMARQALRVLAMAFKPLEATEDHYTAESHEHQLVYAGMVGEIDPERPEVKDAIATAKSAGIRTVMITGDHQITAAAIAERLGIIDQDNIETGVTTGAYLDTISDEQLENEVEHYSVYARVAPEHKVRIVKAWQSAKHNKVVAMTGDGVNDAPSLKQADIGVGMGITGTEVSKGASDMVLADDNFATIVTAVKEGRKVFSNIQKAVQYLLSANLGEVMTLFVATIMGWQILEPIHILWINLVTDTFPAIALGVEDAEADVMEHLPRGRKTSILSGGLLPALFYQGIYEGGITLFVYWFSHYYMNFSNSDAEAIAFLTLSFIQLAHAYNSRSVHKSLFSSNPFANKWLNYATIISSLLLLITVFLPGLNAAFGTIHLVGDPEAFTMWAIILLASLSIILYVEIVKFFLRKSGYADKVENHRS
>NZ_CP014159.1|WP_060777163.1|1330421_1332575_+|RNA-binding-transcriptional-accessory-protein
MSEQFIQQVHDRLKEYRVDQIQAVISMLEAGDTVPFIARYRKEKTGALDEVAIQKIKETHQYVENLEERRQSILKSIDSQGKLTSDLKKNIEASTVLQTLEDLYAPYKKKRRTKATQAKEAGLEPLAEWLYACPTEGNVHQKAETFINEKISSGDEALAGAHEIICEWISENVTFLEHVRTFVFEKGSLVSKKRAKAEDDQETYAVYYDFEEKLKRLKPYQVLAINRAEKEKIVTVSLEIDEFPLAAYLVKEIIKGRPVSTGQLQDAIQDSLERFLLPQAFRYVRSQLNEQAEDSAISTFSTNLEHLLMQQPLKRKVVLGWDPAYRTGCKLAILSPTGQVLDKTVVYPTPPKKDKEGAKKILKDLISKYGIDVIAIGNGTASRESEEFVASFIKEEGLQCTYTIVSESGASVYSASPIAREEFPDYNVEERSAVSIGRRLQDPLAELVKINPQAIGVGQYQHDVSQSKLSDQLDFIVELVVNRVGVDVNTASASLLAHVSGLSKNVAKNLLAYRNEQGKFTNREEFLKVPRLGPKAYEQAAGFLRIREGDNPLDSTGIHPESYPVTLELFEEAGYAIESLHQAEVKQWIKSWNLEALATSHEVGLETLTDIQTALLSPGRDPREEISGPILRQDVMSMEDLKEGMCLQGTVRNVVDFGAFVDIGVKQDGLVHISRLSEKYITDPKDVVSVGDIVEVWVVQIDKNKGRIWLSMIGPKA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014159_1	1.30\|1318389\|33\|NZ_CP014159\|CRT	1318389-1318421	33	NZ_CP028104	Fusobacterium varium ATCC 27725 plasmid pFvar_27725, complete sequence	41842-41874	6	0.818
NZ_CP014159_1	1.15\|1318388\|34\|NZ_CP014159\|CRISPRCasFinder	1318388-1318421	34	NZ_CP028104	Fusobacterium varium ATCC 27725 plasmid pFvar_27725, complete sequence	41842-41875	7	0.794
NZ_CP014159_1	1.21\|1317839\|32\|NZ_CP014159\|CRT	1317839-1317870	32	MT074137	Bacteroides phage DAC16, complete genome	116229-116260	7	0.781
NZ_CP014159_1	1.21\|1317839\|32\|NZ_CP014159\|CRT	1317839-1317870	32	CP016195	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-1, complete sequence	10125-10156	7	0.781
NZ_CP014159_1	1.24\|1318022\|32\|NZ_CP014159\|CRT	1318022-1318053	32	NZ_CP015616	Acinetobacter schindleri strain ACE plasmid p1AsACE, complete sequence	152815-152846	7	0.781
NZ_CP014159_1	1.6\|1317838\|33\|NZ_CP014159\|PILER-CR,CRISPRCasFinder	1317838-1317870	33	MT074137	Bacteroides phage DAC16, complete genome	116229-116261	8	0.758
NZ_CP014159_1	1.26\|1318144\|32\|NZ_CP014159\|CRT	1318144-1318175	32	MN693785	Marine virus AFVG_250M536, complete genome	16173-16204	8	0.75
NZ_CP014159_1	1.28\|1318266\|33\|NZ_CP014159\|CRT	1318266-1318298	33	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	279552-279584	8	0.758
NZ_CP014159_1	1.11\|1318143\|33\|NZ_CP014159\|PILER-CR,CRISPRCasFinder	1318143-1318175	33	MN693785	Marine virus AFVG_250M536, complete genome	16173-16205	9	0.727
NZ_CP014159_1	1.13\|1318265\|34\|NZ_CP014159\|PILER-CR,CRISPRCasFinder	1318265-1318298	34	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	279551-279584	9	0.735
NZ_CP014159_1	1.21\|1317839\|32\|NZ_CP014159\|CRT	1317839-1317870	32	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	1249749-1249780	9	0.719
NZ_CP014159_1	1.22\|1317900\|32\|NZ_CP014159\|CRT	1317900-1317931	32	MN694009	Marine virus AFVG_250M785, complete genome	10566-10597	9	0.719
NZ_CP014159_1	1.26\|1318144\|32\|NZ_CP014159\|CRT	1318144-1318175	32	CP006878	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602a, complete sequence	12424-12455	9	0.719
NZ_CP014159_1	1.29\|1318328\|32\|NZ_CP014159\|CRT	1318328-1318359	32	LR214969	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 15	18062-18093	9	0.719
NZ_CP014159_1	1.29\|1318328\|32\|NZ_CP014159\|CRT	1318328-1318359	32	AP013432	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-U-MedDCM-OCT-S25-C65	8627-8658	9	0.719
NZ_CP014159_1	1.29\|1318328\|32\|NZ_CP014159\|CRT	1318328-1318359	32	MH617495	Microviridae sp. isolate ctca896, complete genome	2128-2159	9	0.719
NZ_CP014159_1	1.24\|1318022\|32\|NZ_CP014159\|CRT	1318022-1318053	32	HQ634193	Cyanophage P-RSM6 genomic sequence	47186-47217	10	0.688
NZ_CP014159_1	1.26\|1318144\|32\|NZ_CP014159\|CRT	1318144-1318175	32	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	645636-645667	10	0.688

1. spacer 1.30|1318389|33|NZ_CP014159|CRT matches to NZ_CP028104 (Fusobacterium varium ATCC 27725 plasmid pFvar_27725, complete sequence) position: , mismatch: 6, identity: 0.818

ttaaaaggtgccaatttagaagatgccgattta-	CRISPR spacer
ataaaaggtaccaatatagaagatg-ggatttgt	Protospacer
 ********.***** *********  *****.

2. spacer 1.15|1318388|34|NZ_CP014159|CRISPRCasFinder matches to NZ_CP028104 (Fusobacterium varium ATCC 27725 plasmid pFvar_27725, complete sequence) position: , mismatch: 7, identity: 0.794

tttaaaaggtgccaatttagaagatgccgattta-	CRISPR spacer
aataaaaggtaccaatatagaagatg-ggatttgt	Protospacer
  ********.***** *********  *****.

3. spacer 1.21|1317839|32|NZ_CP014159|CRT matches to MT074137 (Bacteroides phage DAC16, complete genome) position: , mismatch: 7, identity: 0.781

atttattctcttccataaattttgaaatatct	CRISPR spacer
ataaattatcttccataaattttaaaattatt	Protospacer
**  *** ***************.****  .*

4. spacer 1.21|1317839|32|NZ_CP014159|CRT matches to CP016195 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-1, complete sequence) position: , mismatch: 7, identity: 0.781

atttattctcttccataaa-ttttgaaatatct	CRISPR spacer
atttattaccttccataaatttttggaacaat-	Protospacer
******* .********** *****.**.* .

5. spacer 1.24|1318022|32|NZ_CP014159|CRT matches to NZ_CP015616 (Acinetobacter schindleri strain ACE plasmid p1AsACE, complete sequence) position: , mismatch: 7, identity: 0.781

agatcatac-ttttatggtgatgaagcgatttg	CRISPR spacer
-aataaggcgttatatggtgttgaagcgatttg	Protospacer
 .** * .* ** ******* ************

6. spacer 1.6|1317838|33|NZ_CP014159|PILER-CR,CRISPRCasFinder matches to MT074137 (Bacteroides phage DAC16, complete genome) position: , mismatch: 8, identity: 0.758

tatttattctcttccataaattttgaaatatct	CRISPR spacer
aataaattatcttccataaattttaaaattatt	Protospacer
 **  *** ***************.****  .*

7. spacer 1.26|1318144|32|NZ_CP014159|CRT matches to MN693785 (Marine virus AFVG_250M536, complete genome) position: , mismatch: 8, identity: 0.75

ggtagcaagcggttttttcaaagcgaagattt	CRISPR spacer
gctgccaagcagtttgttcaaagcgaagacag	Protospacer
* *. *****.**** *************.

8. spacer 1.28|1318266|33|NZ_CP014159|CRT matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

aacatctctccttacatgctggctggcatatcc	CRISPR spacer
ggcatctctcctgacatgcaggctggcccggcc	Protospacer
..********** ****** ******* .. **

9. spacer 1.11|1318143|33|NZ_CP014159|PILER-CR,CRISPRCasFinder matches to MN693785 (Marine virus AFVG_250M536, complete genome) position: , mismatch: 9, identity: 0.727

tggtagcaagcggttttttcaaagcgaagattt	CRISPR spacer
agctgccaagcagtttgttcaaagcgaagacag	Protospacer
 * *. *****.**** *************.

10. spacer 1.13|1318265|34|NZ_CP014159|PILER-CR,CRISPRCasFinder matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

caacatctctccttacatgctggctggcatatcc	CRISPR spacer
tggcatctctcctgacatgcaggctggcccggcc	Protospacer
...********** ****** ******* .. **

11. spacer 1.21|1317839|32|NZ_CP014159|CRT matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

atttattctcttccataaattttgaaatatct	CRISPR spacer
ttttatgctcttccataatttttgtgcattca	Protospacer
 ***** *********** ***** .   **

12. spacer 1.22|1317900|32|NZ_CP014159|CRT matches to MN694009 (Marine virus AFVG_250M785, complete genome) position: , mismatch: 9, identity: 0.719

tggttattagagaaagcagattccccgatact	CRISPR spacer
tggatattagataaagcagattctgtgtttgc	Protospacer
*** ******* ***********. .* *  .

13. spacer 1.26|1318144|32|NZ_CP014159|CRT matches to CP006878 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602a, complete sequence) position: , mismatch: 9, identity: 0.719

ggtagcaagcggttttttcaaagcgaagattt	CRISPR spacer
cgcaatgcgcggtttttccaaagcgacgatta	Protospacer
 *.*... *********.******** ****

14. spacer 1.29|1318328|32|NZ_CP014159|CRT matches to LR214969 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 15) position: , mismatch: 9, identity: 0.719

ggctaagaataatcaaaacaaacaaa--tgaccg	CRISPR spacer
aattaagaaaaatcaaaagaaacaaaattaat--	Protospacer
...****** ******** *******  *.*.

15. spacer 1.29|1318328|32|NZ_CP014159|CRT matches to AP013432 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-U-MedDCM-OCT-S25-C65) position: , mismatch: 9, identity: 0.719

ggctaagaataatcaaaacaaacaaatgaccg	CRISPR spacer
aactaagaataaacaaaaaaaacaagagatat	Protospacer
..********** ***** ******. **.

16. spacer 1.29|1318328|32|NZ_CP014159|CRT matches to MH617495 (Microviridae sp. isolate ctca896, complete genome) position: , mismatch: 9, identity: 0.719

ggctaagaataatcaaaacaaacaaatgaccg	CRISPR spacer
aaataagaagaatcacaacaaacaaagagcct	Protospacer
.. ****** ***** ********** ..**

17. spacer 1.24|1318022|32|NZ_CP014159|CRT matches to HQ634193 (Cyanophage P-RSM6 genomic sequence) position: , mismatch: 10, identity: 0.688

agatcatacttttatggtgatgaagcgatttg	CRISPR spacer
aagaagtacttttatgataatgaagcgatcaa	Protospacer
*..  .**********.*.**********. .

18. spacer 1.26|1318144|32|NZ_CP014159|CRT matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 10, identity: 0.688

ggtagcaagcggttttttcaaagcgaagattt	CRISPR spacer
cgtagcaggcggtcttttcaaagcagcattga	Protospacer
 ******.*****.**********.. . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

192030 : 204783

Prochlorococcus_phage(25.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060776247.1\|192030_193329_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.7e-19	29.9
WP_060776248.1\|193321_194605_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_060776249.1\|194614_196165_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.5e-61	43.9
WP_060776250.1\|196161_196740_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.9e-26	39.1
WP_060776251.1\|196741_197791_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	6.0e-62	42.0
WP_082632777.1\|197771_199313_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-56	34.4
WP_082632779.1\|199261_201430_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.4e-134	38.0
WP_060776252.1\|201500_202178_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_060776253.1\|202181_202427_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_060776254.1\|202439_203174_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	1.2e-45	41.7
WP_060776255.1\|203177_204314_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_060776256.1\|204297_204783_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.5e-23	43.4

DBSCAN-SWA_2

528327 : 539517

Streptococcus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060776521.1\|528327_529506_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.3e-85	44.9
WP_060776522.1\|529462_530143_-	VanZ family protein	NA	NA	NA	NA
WP_060776523.1\|530139_531600_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	3.1e-32	30.5
WP_060776524.1\|531603_532314_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.4e-30	33.5
WP_060776525.1\|532446_532806_+	single-stranded DNA-binding protein	A0A0K2CNI9	Brevibacillus_phage	5.2e-10	39.3
WP_060777439.1\|532880_533810_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	3.7e-47	38.2
WP_060776526.1\|533831_534830_-	YvcK family protein	A1IMD5	Streptococcus_phage	2.0e-83	49.8
WP_060776527.1\|534826_535756_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	7.0e-06	29.3
WP_060776528.1\|535839_537561_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	4.3e-166	52.3
WP_060776529.1\|537682_538630_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	3.9e-89	52.7
WP_060776530.1\|538629_539517_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.4e-72	49.8

DBSCAN-SWA_3

667637 : 678552

Enterococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060776623.1\|667637_670196_-	SH3-like domain-containing protein	Q9ZXE4	Bacillus_phage	6.4e-17	39.5
WP_060776624.1\|670481_671396_+	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	2.6e-77	50.7
WP_060777447.1\|671466_672042_+	serine acetyltransferase	NA	NA	NA	NA
WP_082632790.1\|672503_674783_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	1.2e-264	67.3
WP_060776625.1\|674763_675357_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	5.2e-55	60.0
WP_060776626.1\|675464_676865_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_060776627.1\|676888_677341_-	SUF system NifU family Fe-S cluster assembly protein	V5R992	Mycobacterium_phage	7.1e-12	30.9
WP_060776628.1\|677337_678552_-	SufS family cysteine desulfurase	Q2XUY6	environmental_halophage	2.6e-93	41.8

DBSCAN-SWA_4

1320932 : 1330070

Streptococcus_phage(16.67%)

capsid,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082632730.1\|1320932_1322360_+\|portal	phage portal protein	A7J292	Streptococcus_phage	1.2e-145	61.7
WP_082632735.1\|1322343_1323573_+\|capsid	minor capsid protein	D2IYW4	Enterococcus_phage	1.0e-89	56.5
WP_144428660.1\|1323614_1323854_+	hypothetical protein	NA	NA	NA	NA
WP_156407349.1\|1323911_1324067_+	hypothetical protein	NA	NA	NA	NA
WP_060777159.1\|1324565_1324943_-	type II toxin-antitoxin system HicB family antitoxin	A0A0C5AN56	Paenibacillus_phage	3.2e-18	44.4
WP_060777160.1\|1324999_1325194_-	type II toxin-antitoxin system HicA family toxin	A0A0A7RWW9	Clostridium_phage	7.7e-08	49.1
WP_082632731.1\|1325421_1325643_+	HNH endonuclease	A0A1B1IMY5	Lactococcus_phage	8.2e-22	69.1
WP_060777161.1\|1326114_1326855_+	3-oxoacyl-ACP reductase FabG	NA	NA	NA	NA
WP_060777162.1\|1327355_1330070_-	cation-translocating P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	3.5e-74	28.0

DBSCAN-SWA_5

1472018 : 1495989

Streptococcus_phage(82.61%)

integrase

attL 1467495:1467509|attR 1496742:1496756

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1467495:1467509	attL	NA	NA	NA	NA
WP_060777286.1\|1472018_1472345_-	heavy metal-binding domain-containing protein	M4STD1	Rhodobacter_phage	8.7e-12	39.4
WP_144428645.1\|1472796_1473045_-	hypothetical protein	NA	NA	NA	NA
WP_060777287.1\|1473402_1474107_+	YaaA family protein	A0A1X9I5I0	Streptococcus_phage	1.3e-25	36.6
WP_060777288.1\|1474197_1474968_-	3-oxoacyl-ACP reductase	A0A0M4JSW6	Mollivirus	1.4e-07	31.7
WP_060777289.1\|1474967_1475189_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_000420682.1\|1475621_1475936_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|1475951_1476338_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|1476366_1477752_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|1477754_1477907_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|1477929_1479135_+	replication initiation factor	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|1479177_1479399_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|1479515_1480013_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|1479987_1480494_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|1480477_1482925_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000804748.1\|1482927_1485105_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000769868.1\|1485101_1486103_+	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_001224319.1\|1486099_1487032_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
WP_001791010.1\|1487276_1487393_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691727.1\|1487408_1489328_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	100.0
WP_000336323.1\|1489446_1489614_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_001227347.1\|1489673_1490027_-	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000804885.1\|1490531_1490954_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|1490950_1491181_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000814511.1\|1491641_1491845_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|1491926_1493144_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_060777290.1\|1493483_1494023_+	QueT transporter family protein	E7DN70	Pneumococcus_phage	1.8e-09	34.9
WP_060777291.1\|1494189_1495989_+	DNA helicase RecQ	A0A0G2Y0D4	Acanthamoeba_polyphaga_mimivirus	1.1e-76	36.1
1496742:1496756	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1508958 : 1517996

Tupanvirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_169790709.1\|1508958_1510872_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.5e-52	28.8
WP_169790710.1\|1510904_1511849_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	3.0e-113	59.4
WP_060777304.1\|1511860_1512373_+	dihydrofolate reductase	A0A1B2IDT7	Erwinia_phage	7.0e-24	42.3
WP_060777305.1\|1512369_1512954_+	DUF2140 family protein	NA	NA	NA	NA
WP_060777486.1\|1512973_1513195_+	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_082632767.1\|1513216_1514761_+	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	8.3e-20	27.4
WP_060777306.1\|1514774_1515320_+	signal peptidase I	NA	NA	NA	NA
WP_060777307.1\|1515382_1516255_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_082632766.1\|1516256_1517027_+	ribonuclease HII	D2TEQ2	Emiliania_huxleyi_virus	5.0e-26	38.3
WP_060777309.1\|1517105_1517996_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	3.8e-25	38.5

DBSCAN-SWA_7

1566369 : 1572685

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060777352.1\|1566369_1566906_-	hypoxanthine phosphoribosyltransferase	A0A2K9L634	Tupanvirus	1.1e-14	26.9
WP_060777353.1\|1567041_1567581_-	hypoxanthine phosphoribosyltransferase	A0A2K9L634	Tupanvirus	2.3e-09	25.5
WP_060777354.1\|1567720_1568200_-	hypothetical protein	NA	NA	NA	NA
WP_060777491.1\|1568196_1569744_-	hypothetical protein	A0A141HRX5	Bacillus_phage	3.3e-24	23.6
WP_060777355.1\|1569798_1571004_-	ATP-binding protein	A0A172JHT1	Bacillus_phage	7.1e-27	26.7
WP_060777356.1\|1571446_1571995_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	7.0e-38	45.2
WP_060777357.1\|1572049_1572685_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	8.4e-35	36.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage