CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP014944	Staphylococcus schleiferi strain TSCC54	4 crisprs	cas1,cas2,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,WYL,DEDDh,cas3,DinG,cas9,csa3	0	21	9	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP014944_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014944_1

66853-68031

TypeIII

Consensus_repeat	Method
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	CRISPRCasFinder
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	CRT
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	PILER-CR

16 spacers

WYL,cas1,cas2,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6

The CRISPR arrays of NZ_AP014944_1

>merge|NZ_AP014944|1|66853-68031|CRISPRCasFinder,CRT,PILER-CR
GATCGATAACTACCCCGAATAACAGGGGACGAGAATACTTCTCTCGCCATTTCTGCTAATTGTTCTACTTTGGATCGATAACTACCCCGAATAACAGGGGACGAGAATACTAGATACCCAGAACAAAATAGGTCTAACGAAAGATCGATAACTACCCCGAATAACAGGGGACGAGAATTCTATAAGTTCATTAATTCCGATACCTAGATTATCTGATCGATAACTACCCCGAATAACAGGGGACGAGAATTTTTTTCCACCCTTTCAGATCATCTATGATCTTGGATCGATAACTACCCCGAATAACAGGGGACGAGAATAATTTTCTAATTCTATAAGTTCATTAATTCCGATGATCGATAACTACCCCGAATAACAGGGGACGAGAATTATACTATTTACATAATTTTTTATGTGTCTGTCTACGATCGATAACTACCCCGAATAACAGGGGACGAGAATTAATAGTGTTGTTCTCTATTAAAAGATACAATCCTGTGATCGATAACTACCCCGAATAACAGGGGACGAGAATTCTGTAATGTATTCATTTAATGTAATCATAATTTTTTCGATCGATAACTACCCCGAATAACAGGGGACGAGAATTAGACCATTTACCTCATTATATTTATAGTCTTTATTAGATCGATAACTACCCCGAATAACAGGGGACGAGAATTTTTCTTTAACTGTTTTTACTGCCCATTTAATAGTGATCGATAACTACCCCGAATAACAGGGGACGAGAATATAAACCCGTTCAATTCGTTATCTTTAAATTCTTGGATCGATAACTACCCCGAATAACAGGGGACGAGAATACAACTTCGTCATCTTTCATCATTTCTCTTACATCAGATCGATAACTACCCCGAATAACAGGGGACGAGAATATATTTCTTCCATGAATAACACCCTCCTTTTTTCTAGATCGATAACTACCCCGAATAACAGGGGACGAGAATAAGTTAACGGCATTACCTAATAAAAATATTTTAGGGATCGATAACTACCCCGAATAACAGGGGACGAGAACTCATCTTTCATGTCACTGATTAATTCATTTGTAGATCGATAACTACCCCGAATAACAGGGGACGAGAACGGTAATAGTTGCTCAATAGGTAATAAAACGTCGGTGATCGATAACTATCCCGAATAACAGGGGACAGAGTG

>NZ_AP014944|1|1|66853-68031|CRISPRCasFinder
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ACTTCTCTCGCCATTTCTGCTAATTGTTCTACTTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ACTAGATACCCAGAACAAAATAGGTCTAACGAAA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TCTATAAGTTCATTAATTCCGATACCTAGATTATCT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TTTTTTCCACCCTTTCAGATCATCTATGATCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	AATTTTCTAATTCTATAAGTTCATTAATTCCGAT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TATACTATTTACATAATTTTTTATGTGTCTGTCTAC
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TAATAGTGTTGTTCTCTATTAAAAGATACAATCCTGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TCTGTAATGTATTCATTTAATGTAATCATAATTTTTTC
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TAGACCATTTACCTCATTATATTTATAGTCTTTATTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TTTTCTTTAACTGTTTTTACTGCCCATTTAATAGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ATAAACCCGTTCAATTCGTTATCTTTAAATTCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ACAACTTCGTCATCTTTCATCATTTCTCTTACATCA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ATATTTCTTCCATGAATAACACCCTCCTTTTTTCTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	AAGTTAACGGCATTACCTAATAAAAATATTTTAGG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAC	TCATCTTTCATGTCACTGATTAATTCATTTGTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAC	GGTAATAGTTGCTCAATAGGTAATAAAACGTCGGT
GATCGATAACTATCCCGAATAACAGGGGACAGAGTG

>NZ_AP014944|1|1|66853-68031|CRT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ACTTCTCTCGCCATTTCTGCTAATTGTTCTACTTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ACTAGATACCCAGAACAAAATAGGTCTAACGAAA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TCTATAAGTTCATTAATTCCGATACCTAGATTATCT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TTTTTTCCACCCTTTCAGATCATCTATGATCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	AATTTTCTAATTCTATAAGTTCATTAATTCCGAT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TATACTATTTACATAATTTTTTATGTGTCTGTCTAC
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TAATAGTGTTGTTCTCTATTAAAAGATACAATCCTGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TCTGTAATGTATTCATTTAATGTAATCATAATTTTTTC
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TAGACCATTTACCTCATTATATTTATAGTCTTTATTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TTTTCTTTAACTGTTTTTACTGCCCATTTAATAGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ATAAACCCGTTCAATTCGTTATCTTTAAATTCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ACAACTTCGTCATCTTTCATCATTTCTCTTACATCA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ATATTTCTTCCATGAATAACACCCTCCTTTTTTCTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	AAGTTAACGGCATTACCTAATAAAAATATTTTAGG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAC	TCATCTTTCATGTCACTGATTAATTCATTTGTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAC	GGTAATAGTTGCTCAATAGGTAATAAAACGTCGGT
GATCGATAACTATCCCGAATAACAGGGGACAGAGTG

>NZ_AP014944|1|1|67207-67959|PILER-CR
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTATACTATTTACATAATTTTTTATGTGTCTGTCTAC
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTAATAGTGTTGTTCTCTATTAAAAGATACAATCCTGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTCTGTAATGTATTCATTTAATGTAATCATAATTTTTTC
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTAGACCATTTACCTCATTATATTTATAGTCTTTATTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTTTTCTTTAACTGTTTTTACTGCCCATTTAATAGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TATAAACCCGTTCAATTCGTTATCTTTAAATTCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TACAACTTCGTCATCTTTCATCATTTCTCTTACATCA
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TATATTTCTTCCATGAATAACACCCTCCTTTTTTCTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TAAGTTAACGGCATTACCTAATAAAAATATTTTAGG
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	CTCATCTTTCATGTCACTGATTAATTCATTTGTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014944.1\|WP_001038847.1\|57077_59066_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_000281076.1\|69009_69315_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09638_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|273699
NZ_AP014944.1\|WP_001015575.1\|60729_62346_+\|primase	unknown	unknown	gnl\|CDD\|225913
NZ_AP014944.1\|WP_060829142.1\|62570_64250_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
NZ_AP014944.1\|WP_060829144.1\|81625_82348_+\|DUF4391-domain-containing-protein	unknown	unknown	gnl\|CDD\|379562
NZ_AP014944.1\|WP_000655859.1\|68104_69010_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_AP014944.1\|WP_000286998.1\|72031_72676_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_AP014944.1\|WP_000175888.1\|64338_64677_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368749
NZ_AP014944.1\|WP_000599362.1\|71604_72030_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|273844
NZ_AP014944.1\|WP_072093071.1\|66127_66439_-\|DUF3387-domain-containing-protein	unknown	unknown	gnl\|CDD\|378743
NZ_AP014944.1\|WP_001024805.1\|64770_65082_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368760
NZ_AP014944.1\|WP_060829143.1\|78367_81625_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|350769
NZ_AP014944.1\|WP_000359017.1\|69328_71602_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_AP014944.1\|WP_000608705.1\|75888_76623_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_AP014944.1\|WP_001092190.1\|65096_65600_+\|DUF1643-domain-containing-protein	unknown	unknown	gnl\|CDD\|226783
NZ_AP014944.1\|WP_001058155.1\|60361_60730_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_000208937.1\|72686_73595_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|273866
NZ_AP014944.1\|WP_000153149.1\|73597_74620_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
NZ_AP014944.1\|WP_000750311.1\|55986_56916_+\|HTH-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_AP014944.1\|WP_001015193.1\|65614_65836_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP014944.1\|WP_000281076.1\|69009_69315_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	4.06918e-22
NZ_AP014944.1\|WP_001015575.1\|60729_62346_+\|primase	gnl\|CDD\|225913	COG3378, COG3378, Phage associated DNA primase [General function prediction only].	3.31891e-21
NZ_AP014944.1\|WP_060829142.1\|62570_64250_+\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	6.75057e-34
NZ_AP014944.1\|WP_060829144.1\|81625_82348_+\|DUF4391-domain-containing-protein	gnl\|CDD\|379562	pfam14335, DUF4391, Domain of unknown function (DUF4391). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 220 and 257 amino acids in length.	3.0036e-34
NZ_AP014944.1\|WP_000655859.1\|68104_69010_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.00185e-113
NZ_AP014944.1\|WP_000286998.1\|72031_72676_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	7.36094e-106
NZ_AP014944.1\|WP_000175888.1\|64338_64677_+\|hypothetical-protein	gnl\|CDD\|368749	pfam06106, SAUGI, S. aureus uracil DNA glycosylase inhibitor. Uracil-DNA glycosylase inhibitors, are DNA mimic proteins that prevent the DNA binding sites of UDGs (Uracil DNA glycosylase) from interacting with their DNA substrate. SSP0047 (SAUGI; for Staphylococcus aureus uracil-DNA glycosylase inhibitor) acts as a uracil-DNA glycosylase inhibitor that breaks the uracil-removing activity of S. aureus uracil-DNA glycosylase (SAUDG) pfam03167. The SAUGI/SAUDG complex has been determined, and shows that SAUGI binds to the SAUDG DNA binding region via several strong interactions, by using a hydrophobic pocket to hold SAUDG's protruding residue (i.e. SAUDG Leu184, E. coli UDG Leu191 and B. subtilis UDG Phe191). By binding to SAUDG in this way, SAUGI thus prevents SAUDG from binding to its DNA substrate and performing DNA repair activity.	8.57061e-38
NZ_AP014944.1\|WP_000599362.1\|71604_72030_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	7.59929e-21
NZ_AP014944.1\|WP_072093071.1\|66127_66439_-\|DUF3387-domain-containing-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	4.08117e-39
NZ_AP014944.1\|WP_001024805.1\|64770_65082_+\|hypothetical-protein	gnl\|CDD\|368760	pfam06124, DUF960, Staphylococcal protein of unknown function (DUF960). This family consists of several hypothetical proteins from several species of Staphylococcus. The function of this family is unknown.	6.74747e-26
NZ_AP014944.1\|WP_000359017.1\|69328_71602_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NZ_AP014944.1\|WP_000608705.1\|75888_76623_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	7.10684e-15
NZ_AP014944.1\|WP_001092190.1\|65096_65600_+\|DUF1643-domain-containing-protein	gnl\|CDD\|226783	COG4333, COG4333, Uncharacterized protein conserved in bacteria [Function unknown].	1.3268e-79
NZ_AP014944.1\|WP_060829143.1\|78367_81625_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.2123e-43
NZ_AP014944.1\|WP_000153149.1\|73597_74620_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.06095e-17
NZ_AP014944.1\|WP_000750311.1\|55986_56916_+\|HTH-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.16329e-26
NZ_AP014944.1\|WP_000208937.1\|72686_73595_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	3.0078e-40

>NZ_AP014944.1|WP_072093071.1|66127_66439_-|DUF3387-domain-containing-protein
MLSDDFLKDVEGLKQKNVAVELLNRLLKGQVKSLMKTNATVSKRFSEMLRNSINKYNSRSIETSKVIEELIQLAKDIKQEQQRGNELGLNSDEIAFLRCFSFT
>NZ_AP014944.1|WP_001015193.1|65614_65836_+|hypothetical-protein
MNHETTHSDWRTVANCLASQNYISIVKGLVHHFTAIEDEEILDKIYEDFMNNGSITTVLNNDLQDIINYYLSK
>NZ_AP014944.1|WP_001092190.1|65096_65600_+|DUF1643-domain-containing-protein
MNTIKSTIHTEAIFSDDEQHRYLLKKTWDEKKPVCTVITMYPHLDGVLSLDLTTVLILNQLANSEQYGAVYLVNLFSNIKTPENLKHIKEPYDKHTDIHLMKAISESDTVILAYGAYAKRPVVVERVEQVMEMLKPHKKKVKKLINPATNDIMHPLNPKARQKWILK
>NZ_AP014944.1|WP_001024805.1|64770_65082_+|hypothetical-protein
MNINRYITRGISEQLSLDLQILLWHMVEEKDNQPHTDYLHIFKLQEDDNMLSITHEQEQPAYKLEYHYINYEKNQNALPKKVYVIREDDVDVFYYVMLLPEEY
>NZ_AP014944.1|WP_000175888.1|64338_64677_+|hypothetical-protein
MTLSKQLKTYITERFKLNYQETWACETIDAVAEDVLPEKYIKNSPLEHKILNTFTYYNDELHEISIYPFLCYLDKELVAIGYLDNFDLDFIFLNDTHQIIIDERYLLQKGGE
>NZ_AP014944.1|WP_060829142.1|62570_64250_+|recombinase-family-protein
MKGKIALYSRVSTSEQSEHGYSEKEQEQLLIKEVMKNFPGYDYETYTDSGISGKNIEGRPAMKRLLQDVKDNKIEMVLSWKLNRISRSMRDVFNIIHEFKEHDVGYKSISENIDTSNASGEVLVTMFGLIGSIERQTLISNVKLSMNAKARSGEAITGRVLGYKLSLNPLTQKNDLVIDENEAHIVREIFDLYLNHNKGFKAITTILNQKGYRTINQKPFSVFGVKYILNNPVYKGYVRFNNHQNWAVQRRSGKSDKNDVILVKGKHEAIISEEVFDQVHEKLASKSFKPGRPIGGDFYLRGLIKCPECGNNMVCRRTYYKTKKSKERTIKRYYICSLFNRSGSSACHSNAINAEVVERVINVHLNRILSQPNVIKQIASSVIEELKQKHSKQTEIKYDIDSLEKQKAKVKTQQERLLELFLDDEMDSEMLKAKQSEMNQQLEVLDQQIKEAKQANQSQDDIPNFDKLKARLILMITRFSVYLRKATPEAKNQLMKMLIDSIEITTDKQVKLVRYKIDESLIPQSLKKDWGSFFIPKFNFVINVTKKNRIENLSLLPLF
>NZ_AP014944.1|WP_001015575.1|60729_62346_+|primase
MNHILEMLIKLLKVGMEAIDRKGLIAILTSSIGNDEMDDSEQAVMVYNELIDKLQLNIPKDVDYRPNIYSYFGIQKKPNDTILVEMMICIFHIKRFDSELFVFKDKGWQKVSEDELQGLISKMIQVLLVDYKPSLSTLKNVVDGIQKSTDIEKLVEHRQYIGCGRNMFNLKTFKVVDNDLEIFPKTRLDLELDINDTITDKIPPNFKQYMLELANYDHDLQYFLFQHMAVLLTADTKLRRGLFLYGTAKNGKSVYIKLVKSFFYSNDIVSKTLNELGGRFDKESLIGKRIMASDEVGKANIDEATVNDFKKLLSVEPIHADRKGRTQVEVTLDLKLIFNTNAVLNFPSSHAKALERRIAVIPCEYYVEKADPDLIEKLQDEKKEIFLYLMYVYKQIVKNDIEYLQNDRVTEISHDWLNFGYEFVSSKSANIAHQKACINLLRKLIEIKPGSRIKVSRLNEVIRDEIKVSSQVINDLVQANFNVQSRLNNGYKYWVDLGWKETDKKDDMISFDKNENVTDDEFLYEDDLNLGWEDFDDE
>NZ_AP014944.1|WP_001058155.1|60361_60730_+|hypothetical-protein
MNNDRGKSLQIPQSTLLKEGSIYVATLHSVYEKNFSGDIKHQFTYEVELNQETHYVNRNITVKSMSHQLSIADWIKRHSNYNVNHINYDPYIDRKHLVLVGQYNGNYYIQDVAPLDEFGGVL
>NZ_AP014944.1|WP_001038847.1|57077_59066_+|hypothetical-protein
MNKNITALKSTENTTYMQYTVHIDDQIINNIKECTKKFKILPMEDKIPLSPLLQPEYAGEVQDFISTYEQFMINFGKVILDSQGIKIQFESESLSSIQRGIQEHCYLNERTNDIDVTKEWYLCKFSNQILEEDKNQLYNALKQLMNDSKNKKQAFQEVFKVHIDIYLYNKEKSEYKYQVSSYFNLVKENPKITYKKRHLQEKQGVKGTTFTNKLKLLNKMYGVDVAKYQPFYNSNNPEYERGQFGERYISQRSNYEFNRLQYQIIDMLSKILDKHPLPKSDNNYKHIPTIEKAILSGDSHSFYEYFEDIMKEIISMENSSLKEKLLTDFTYQSQCRWYSESEKLKLQLESFMHKVLESNYYEGNKLYRMLSHAIEETINEADEDKVHFNYFKDYFLTDGGVKNWEQISEKITEFNGKVINDIQNEYNKIQFNNANRNQKLNFNYLYHCFEFSNNLVKARVNGNRGYILYFVDKYKIKMPFLDQLLINYLNQEIGQESINYNMQTLFEKERYDRSSTIEKLVATSKFKYEKDDSDLFKQLFNDVENSIDRLGIYLLNNGINSNDENARYYRSFLKELSRIKSKLTPFSLEISKSSGREQHYPDDAIDDKDERRKNKEETYHAFDDKSDIDSKLKNKINVSIDNLLSVKIKSNLYDISPNTKKQ
>NZ_AP014944.1|WP_000750311.1|55986_56916_+|HTH-domain-containing-protein
MKKSVRLYNMIEYCNENRNFKLNDLMSEFNISRSTALRDIKEIEALGVPLYSNPGKNGGYTIIGNRDQTKIAISDEELKALVFTLSSISNVSNLPFQTEYQEILKKLYNNSNKKELINQYNDLFQYFNEDKYQFKSYKLFNEIIRLIIENKSFETCYSQNYIKEQYKGIGIMYKNHQWYFVVANIESKLVNLLNISKIKELYEMGETQECNDITMQNFQQFMVKNETAIDILIRSNVMGLNILKGYLWSDYMIENIDEETYLFKSKVNAKDIDFIAKLIVTGGVNVKVETPNSLKNAVKVELTKIINMY
>NZ_AP014944.1|WP_000655859.1|68104_69010_+|type-II-CRISPR-associated-endonuclease-Cas1
MKDVIYVENHYFVTVKENSIKFRNVIDKSEKFYLFEEIEAIIFDHYKSYFSHKLVIKCIENDIAIIFCDKKHSPLTQLISSYGMTHRLQRIQSQFQLSGRTRDRIWKKIVVNKIINQSKCLENNLHNENVKLLVNLAKDVSSGDKSNKEAQAARIYFKDLYGKQFKRGRYNDIINSGLNYGYSILRSFIKKELALHGFEMSLGINHRSKENPFNLADDIIEVFRPFVDNIVYEIVFKKNINTFDVNEKKLLLNVLYEKCIIDKKVVRLLDSVKIVIQSLIRCYEENTPTYLLLPKMIEVGN
>NZ_AP014944.1|WP_000281076.1|69009_69315_+|CRISPR-associated-endonuclease-Cas2
MYLLVSFDLPRDTKFERRVASKYRTRLLELGFSMKQFSLYERYVSDVQKKDKILEILQQEIPDTGSITLYVLPDEVNNSQITILGKEVKVVVRKEPKLIFL
>NZ_AP014944.1|WP_000359017.1|69328_71602_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MDKKTTLMYGSLLHDIGKIIYRSNDHAFARGTHSKLGYNFLSQFSEFKDNEVLDSIAYHHYKELAKANLANDNTAYITYIADNIASGIDRRDVIEEGDEEYEKQAFNFDKYTPLYSVFNIVNSEKLKQISGKFKFSNESNIEYPKTENIQYSSGNYTTLMKDMSYDLEHKLSIKEDTFPSLLQWTESLWQYVPSSTNKNQLIDISLYDHSRITCAIASCIFDYLNENNIHNYKDELFTKYENTKEFYQKEAFLLLSMDMSGIQDFIYNISGSKALKSLRSRSFYLEIMLEVIVDQLLEKLELTRANLLYTGGGHAYLLVSNTDKGKEKINQFNTELKNWFMSEFTTDLSLSIAFEKCSGNDLMNTSGNYRNIWRNVSSKLSDIKAHKYSSEDILKLNHFHSYGDRECKECLRSDIDINDDGLCSICEGIINISNDLRDKSFFVLSETGKLKMPFDKFISVIDYEEAERLAQNNNHIRIYSKNKPYIGVGISTNLWMCDYDYASQNKDMREKGIGSYVEREEGIKRLGVVRADIDNLGATFISGIPEKYNSISRTATLSRQLSLFFKYELNHLLENYQITAIYSGGDDLFLIGAWDDIIEVSVYINEKFKDFTLGKLTMSAGVGMFSGKYPISKMAFETGLLEEAAKTDEKNQIALWVQEKVYNWDEFKKYILEEKLLVLQHGFSQTDEHGKAFIYKMLALLRNNETINIARLAYLLARSKMTEEFTSKIFNWAQNDKDKNQLITALEYYVYQIREVD
>NZ_AP014944.1|WP_000599362.1|71604_72030_+|type-III-A-CRISPR-associated-protein-Csm2
MILAKTKSGKKIDLTFAHEVVKSNVKTVKDKRGKENQVLFNGLTTSKLRNLMEQVNRLYTIAFNSTEDQLNEEFIDELEYLKIKFYYEAGREKSVDEFLKKTLMFPIIDRVIQKESKKFFLDYCKYFEALVAYAKYYQKED
>NZ_AP014944.1|WP_000286998.1|72031_72676_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MYSKIKISGTIEVVTGLHIGGGGESSMIGAIDSPVVRDLQTKLPIIPGSSIKGKMRSLLAKHFGLKMKQENHNQDDESVLRLFGSSEKGNIQRARLQISDAFFSEKTKEHFAQNDIAYTETKFENTINRLTAVANPRQIERVTRGSEFDFVFIYNVDEESQVENDFENIEKAIHLLENDYLGGGGTRGNGRIQFNDITIETVVGEYDSTNLKIK
>NZ_AP014944.1|WP_000208937.1|72686_73595_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MTTKVFKLSFKTPVHFGKKRLSDGEMTITSDTLFSALFIEALQLGIETDWLLNDLIISDTFPYENEIYYLPKPLIKIESKEEGNHKAFKKLKYVPVHHYNQYLNGELSAEDATDLNDIFSIGHFSLQTKVSLSAQEIDSSADSEPYSVGTFTFEPEAGLYFIAKGSEETLDQLKDIMTSLQYSGLGGKRNAGYGQFEYEIINNQQLFKLLNQNGEHSILLSTAMAKEDEIKSALKEARYILNKRSGFIQSTNYSEMLVKKSDFYSFSSGSVFKNIFNGDVFNVGHNGKHPVYRYAKPLWLEV
>NZ_AP014944.1|WP_000153149.1|73597_74620_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MTIKNYEVVIKTLGPVHIGSGQVMKKQDYIYDFYNSKVYMINGNKLVKFLKRKNILDTYQNFLRYPPKNPRENGLKDYLDAQNVKQSEWKAFVSYSEKVNQGKKYGNIRPKPLNDLHLMVRDGQNKVYLPGSSIKGAIKTALVSKYNNEKNTDVYSKIKVSDSEPIDERHLAIYQKIDINKSEKPMPLYRECVDVDTEIKFKLTIEDEIYSINEIEQSIQDFYKNYYDKWLVGFKETKGGRRFALEGGMPDVLNQNILFLGAGAGFVSKTTHYQLKSREQAKRDSFDILTKKFRRTYGKMKEMPSNVPVALKGTTNQSLHVSYQQGMCKISFQELNNEVL
>NZ_AP014944.1|WP_000608705.1|75888_76623_+|CRISPR-associated-endoribonuclease-Cas6
MINKITVELDLPDSIRFQYLGSILHGVLMDYLPNDIADQLHHEFAYSPLKQRIYHKNKKVIWEIVCMSDRLFNEIAELFTSKNRLFLKYYQVYIEIYSFNIEKVNVQNIMNQLLETEELNRYVRINIQTPMSFKYQSNYMIFPEVKRFFRSIMIQFDAFFEEYKMYDKETLDFLEKNINIVDYKLKSTRFNLEKVKIPSFTGEIVFKIKGPLPFLQLTHFLLKFGEFSGSGMKTSLGMGKYSII
>NZ_AP014944.1|WP_060829143.1|78367_81625_+|DEAD/DEAH-box-helicase-family-protein
MELKLIDNKGDNTLENLISEKVTKHSKISIQTAAFSIFAFHALQKEIKRSKGLRLVLTKSFFEKEETSFLKRYEIAQSEEDISGNKYEIKLRNKMNTAFIARETARLIEEKVKVHQLGPNQNALDELLIENEADIEGNVVVPSMFKFTSDGLGLTESNNVSSMTGIIGEPNHLAGLKDDFDAVWKDPKKSKEVTGKVLEKVRTIYQENPPEWIYFVSLYHIFHDKLSELDEQDIAPEGSGFKDSVIWNKLYQFQKDGVMGLIRKLEKYNGEILADSVGLGKTFSALAVIKYFELQRKRVLVLAPKRLRDNWTLYTRPDVRNVLVDDYFNYTVLNHTDLSRYKGESDGIKLDTFLWSDFDLVVIDESHNFRNNDTSVNRETKTRYQRLMEDIIQKGRKTKVLMLSATPINNRMNDLKNQIGFITEGKTDALAKYGVDDIDTTLRLAQQAFNQWMELDESERTTQSFLDKVNPDYFKLLDMLTIARSRKHIEKYYDTTSLGDFPERLKPMTVKPNIDASGQFPDLQDVYDSIGYLNMAMYQPLQYVLSTKRKRYEELYDTKVKEGKSSFRQVDREQALAKLIRANLFKRLESSIYSFGSTLDRMVGGIEDILKKIKEHQAGNVEMPSITDFDDEDLESAFDEQAVGTKTKILIGDMDLVKWSQALNEDLETLKELQTVTHRVTPEKDDKLMDLEKILKHKYEHPINGNNKKVIIFTAFADTANYLYENLADKVKRLCGLNSALVTGGSTPNKTTMKGVAVNDMSDILTNFSPISKGRDQINPNATEEIDLLIATDTISEGQNLQDADYLINYDIHWNPVRVIQRFGRIDRIGSRNKQIQLVNFWPNVDLDTYLNLEQRVKGRMVMLNTAATGEDDLLNIKSNKEMNDLKYRKKQLEQLQTQVIDLEDVNGAISITDMTFNDFKADLQNALKEHEKLLNEAPLGMYAITDTTNFPEAEPGVILTLKQQTNDLGQENSILPYIVVYMRMDGTVKINYMYAKQVLDFFKKLTVGKKTVNQPLVDEFYEETNGGKDMSAYSEILSKAIEAIRGKQDEVGMGSLFSPGGTSVQTELLDDLDDVELISFLIIR
>NZ_AP014944.1|WP_060829144.1|81625_82348_+|DUF4391-domain-containing-protein
MSELESKDIIKWWKFPSATIINRNLPKTQIYPHMKNTADKQFLQDSVQSIYMLASLKTDNTHIAVYEDDKELYQEIQFLYVKTKDKGDSTKIYKMLSHLIPYPLVILTDEPDSFTIYMGRFEKLSTGFLKLVNVYPSPVYQDENLEEVLQQISLIDLPRQNLKTFYDGLRDEIATATAKSQYGEAVGNITGEEKDQLDALKKQIEDLRGQIKKERQLNRKIDMQMKLKKLKDELLSKINQ

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Crispr_ID: NZ_AP014944_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014944_2

76758-77005

TypeIII

Consensus_repeat	Method
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	CRISPRCasFinder
ATTCGATAACTACCNCCGTAGAAGAGGGGACGAG	CRT

3 spacers

cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas2,cas1

The CRISPR arrays of NZ_AP014944_2

>merge|NZ_AP014944|2|76758-77005|CRISPRCasFinder,CRT
ATTCGATAACTACCCCGTAGAAGAGGGGACGAGAACTCTTCTAAGACGCGATATGATTCTAATTGGTCTTCATTCGATAACTACCCCCGTAGAAGAGGGGACGAGAACTGATATACTCCTTTACCATGTATTAATTCTGGACCACTATTCGATAACTACCCCGTAGAAGAGGGGACGAGAACTCATATTCGATCGTGTATATCAAAACTTTATGCATTCGATAACTACCCCGTAGAAGAGGGGACGAG

>NZ_AP014944|2|2|76758-77005|CRISPRCasFinder
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	AACTCTTCTAAGACGCGATATGATTCTAATTGGTCTTCA
TTCGATAACTACCCCCGTAGAAGAGGGGACGAG	AACTGATATACTCCTTTACCATGTATTAATTCTGGACCACT
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	AACTCATATTCGATCGTGTATATCAAAACTTTATGC
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG

>NZ_AP014944|2|2|76758-77005|CRT
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	AACTCTTCTAAGACGCGATATGATTCTAATTGGTCTTC
ATTCGATAACTACCCCCGTAGAAGAGGGGACGA	GAACTGATATACTCCTTTACCATGTATTAATTCTGGACCACT
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	AACTCATATTCGATCGTGTATATCAAAACTTTATGC
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014944.1\|WP_060829146.1\|84404_87395_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226115
NZ_AP014944.1\|WP_000608705.1\|75888_76623_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_AP014944.1\|WP_060829145.1\|82383_84384_+\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|225100
NZ_AP014944.1\|WP_001015193.1\|65614_65836_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_000599362.1\|71604_72030_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|273844
NZ_AP014944.1\|WP_060829149.1\|94664_95495_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380391
NZ_AP014944.1\|WP_000655859.1\|68104_69010_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_AP014944.1\|WP_000286998.1\|72031_72676_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_AP014944.1\|WP_060829144.1\|81625_82348_+\|DUF4391-domain-containing-protein	unknown	unknown	gnl\|CDD\|379562
NZ_AP014944.1\|WP_000281076.1\|69009_69315_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09638_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|273699
NZ_AP014944.1\|WP_060829143.1\|78367_81625_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|350769
NZ_AP014944.1\|WP_000359017.1\|69328_71602_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_AP014944.1\|WP_082704387.1\|89969_90965_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_AP014944.1\|WP_169925607.1\|101200_101374_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_060829151.1\|99830_100811_-\|tRNA-dihydrouridine-synthase	unknown	unknown	gnl\|CDD\|223120
NZ_AP014944.1\|WP_060829150.1\|95496_97713_-\|alpha-galactosidase	unknown	unknown	gnl\|CDD\|225882
NZ_AP014944.1\|WP_072093071.1\|66127_66439_-\|DUF3387-domain-containing-protein	unknown	unknown	gnl\|CDD\|378743
NZ_AP014944.1\|WP_000153149.1\|73597_74620_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
NZ_AP014944.1\|WP_060829148.1\|91254_94266_+\|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|380076
NZ_AP014944.1\|WP_000208937.1\|72686_73595_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|273866

Protein	Function_ID	Function_description	E-value
NZ_AP014944.1\|WP_000608705.1\|75888_76623_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	7.10684e-15
NZ_AP014944.1\|WP_060829145.1\|82383_84384_+\|site-specific-DNA-methyltransferase	gnl\|CDD\|225100	COG2189, COG2189, Adenine specific DNA methylase Mod [DNA replication, recombination, and repair].	2.76084e-28
NZ_AP014944.1\|WP_060829146.1\|84404_87395_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226115	COG3587, COG3587, Restriction endonuclease [Defense mechanisms].	0
NZ_AP014944.1\|WP_000599362.1\|71604_72030_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	7.59929e-21
NZ_AP014944.1\|WP_060829149.1\|94664_95495_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|380391	cd06986, cupin_MmsR-like_N, AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain. This family contains bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included is MmsR, a bacterial transcriptional regulator thought to positively regulate the expression of the mmsAB operon. The mmsAB operon contains two structural genes involved in valine metabolism: mmsA which encodes methylmalonate-semialdehyde dehydrogenase, and mmsB which encodes 3-hydroxyisobutyrate dehydrogenase. The cupin domain of members of this subfamily does not contain a metal binding site.	2.81812e-33
NZ_AP014944.1\|WP_000655859.1\|68104_69010_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.00185e-113
NZ_AP014944.1\|WP_000286998.1\|72031_72676_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	7.36094e-106
NZ_AP014944.1\|WP_060829144.1\|81625_82348_+\|DUF4391-domain-containing-protein	gnl\|CDD\|379562	pfam14335, DUF4391, Domain of unknown function (DUF4391). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 220 and 257 amino acids in length.	3.0036e-34
NZ_AP014944.1\|WP_000281076.1\|69009_69315_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	4.06918e-22
NZ_AP014944.1\|WP_060829143.1\|78367_81625_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.2123e-43
NZ_AP014944.1\|WP_000359017.1\|69328_71602_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NZ_AP014944.1\|WP_082704387.1\|89969_90965_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	7.23106e-29
NZ_AP014944.1\|WP_060829151.1\|99830_100811_-\|tRNA-dihydrouridine-synthase	gnl\|CDD\|223120	COG0042, COG0042, tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis].	3.73002e-92
NZ_AP014944.1\|WP_060829150.1\|95496_97713_-\|alpha-galactosidase	gnl\|CDD\|225882	COG3345, GalA, Alpha-galactosidase [Carbohydrate transport and metabolism].	0
NZ_AP014944.1\|WP_072093071.1\|66127_66439_-\|DUF3387-domain-containing-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	4.08117e-39
NZ_AP014944.1\|WP_000153149.1\|73597_74620_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.06095e-17
NZ_AP014944.1\|WP_060829148.1\|91254_94266_+\|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein	gnl\|CDD\|380076	pfam17961, Big_8, Bacterial Ig domain. This entry represents a bacterial Ig-fold domain that is found in a wide range of bacterial cell surface adherence proteins.	1.39244e-18
NZ_AP014944.1\|WP_000208937.1\|72686_73595_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	3.0078e-40

>NZ_AP014944.1|WP_000608705.1|75888_76623_+|CRISPR-associated-endoribonuclease-Cas6
MINKITVELDLPDSIRFQYLGSILHGVLMDYLPNDIADQLHHEFAYSPLKQRIYHKNKKVIWEIVCMSDRLFNEIAELFTSKNRLFLKYYQVYIEIYSFNIEKVNVQNIMNQLLETEELNRYVRINIQTPMSFKYQSNYMIFPEVKRFFRSIMIQFDAFFEEYKMYDKETLDFLEKNINIVDYKLKSTRFNLEKVKIPSFTGEIVFKIKGPLPFLQLTHFLLKFGEFSGSGMKTSLGMGKYSII
>NZ_AP014944.1|WP_000153149.1|73597_74620_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MTIKNYEVVIKTLGPVHIGSGQVMKKQDYIYDFYNSKVYMINGNKLVKFLKRKNILDTYQNFLRYPPKNPRENGLKDYLDAQNVKQSEWKAFVSYSEKVNQGKKYGNIRPKPLNDLHLMVRDGQNKVYLPGSSIKGAIKTALVSKYNNEKNTDVYSKIKVSDSEPIDERHLAIYQKIDINKSEKPMPLYRECVDVDTEIKFKLTIEDEIYSINEIEQSIQDFYKNYYDKWLVGFKETKGGRRFALEGGMPDVLNQNILFLGAGAGFVSKTTHYQLKSREQAKRDSFDILTKKFRRTYGKMKEMPSNVPVALKGTTNQSLHVSYQQGMCKISFQELNNEVL
>NZ_AP014944.1|WP_000208937.1|72686_73595_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MTTKVFKLSFKTPVHFGKKRLSDGEMTITSDTLFSALFIEALQLGIETDWLLNDLIISDTFPYENEIYYLPKPLIKIESKEEGNHKAFKKLKYVPVHHYNQYLNGELSAEDATDLNDIFSIGHFSLQTKVSLSAQEIDSSADSEPYSVGTFTFEPEAGLYFIAKGSEETLDQLKDIMTSLQYSGLGGKRNAGYGQFEYEIINNQQLFKLLNQNGEHSILLSTAMAKEDEIKSALKEARYILNKRSGFIQSTNYSEMLVKKSDFYSFSSGSVFKNIFNGDVFNVGHNGKHPVYRYAKPLWLEV
>NZ_AP014944.1|WP_000286998.1|72031_72676_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MYSKIKISGTIEVVTGLHIGGGGESSMIGAIDSPVVRDLQTKLPIIPGSSIKGKMRSLLAKHFGLKMKQENHNQDDESVLRLFGSSEKGNIQRARLQISDAFFSEKTKEHFAQNDIAYTETKFENTINRLTAVANPRQIERVTRGSEFDFVFIYNVDEESQVENDFENIEKAIHLLENDYLGGGGTRGNGRIQFNDITIETVVGEYDSTNLKIK
>NZ_AP014944.1|WP_000599362.1|71604_72030_+|type-III-A-CRISPR-associated-protein-Csm2
MILAKTKSGKKIDLTFAHEVVKSNVKTVKDKRGKENQVLFNGLTTSKLRNLMEQVNRLYTIAFNSTEDQLNEEFIDELEYLKIKFYYEAGREKSVDEFLKKTLMFPIIDRVIQKESKKFFLDYCKYFEALVAYAKYYQKED
>NZ_AP014944.1|WP_000359017.1|69328_71602_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MDKKTTLMYGSLLHDIGKIIYRSNDHAFARGTHSKLGYNFLSQFSEFKDNEVLDSIAYHHYKELAKANLANDNTAYITYIADNIASGIDRRDVIEEGDEEYEKQAFNFDKYTPLYSVFNIVNSEKLKQISGKFKFSNESNIEYPKTENIQYSSGNYTTLMKDMSYDLEHKLSIKEDTFPSLLQWTESLWQYVPSSTNKNQLIDISLYDHSRITCAIASCIFDYLNENNIHNYKDELFTKYENTKEFYQKEAFLLLSMDMSGIQDFIYNISGSKALKSLRSRSFYLEIMLEVIVDQLLEKLELTRANLLYTGGGHAYLLVSNTDKGKEKINQFNTELKNWFMSEFTTDLSLSIAFEKCSGNDLMNTSGNYRNIWRNVSSKLSDIKAHKYSSEDILKLNHFHSYGDRECKECLRSDIDINDDGLCSICEGIINISNDLRDKSFFVLSETGKLKMPFDKFISVIDYEEAERLAQNNNHIRIYSKNKPYIGVGISTNLWMCDYDYASQNKDMREKGIGSYVEREEGIKRLGVVRADIDNLGATFISGIPEKYNSISRTATLSRQLSLFFKYELNHLLENYQITAIYSGGDDLFLIGAWDDIIEVSVYINEKFKDFTLGKLTMSAGVGMFSGKYPISKMAFETGLLEEAAKTDEKNQIALWVQEKVYNWDEFKKYILEEKLLVLQHGFSQTDEHGKAFIYKMLALLRNNETINIARLAYLLARSKMTEEFTSKIFNWAQNDKDKNQLITALEYYVYQIREVD
>NZ_AP014944.1|WP_000281076.1|69009_69315_+|CRISPR-associated-endonuclease-Cas2
MYLLVSFDLPRDTKFERRVASKYRTRLLELGFSMKQFSLYERYVSDVQKKDKILEILQQEIPDTGSITLYVLPDEVNNSQITILGKEVKVVVRKEPKLIFL
>NZ_AP014944.1|WP_000655859.1|68104_69010_+|type-II-CRISPR-associated-endonuclease-Cas1
MKDVIYVENHYFVTVKENSIKFRNVIDKSEKFYLFEEIEAIIFDHYKSYFSHKLVIKCIENDIAIIFCDKKHSPLTQLISSYGMTHRLQRIQSQFQLSGRTRDRIWKKIVVNKIINQSKCLENNLHNENVKLLVNLAKDVSSGDKSNKEAQAARIYFKDLYGKQFKRGRYNDIINSGLNYGYSILRSFIKKELALHGFEMSLGINHRSKENPFNLADDIIEVFRPFVDNIVYEIVFKKNINTFDVNEKKLLLNVLYEKCIIDKKVVRLLDSVKIVIQSLIRCYEENTPTYLLLPKMIEVGN
>NZ_AP014944.1|WP_072093071.1|66127_66439_-|DUF3387-domain-containing-protein
MLSDDFLKDVEGLKQKNVAVELLNRLLKGQVKSLMKTNATVSKRFSEMLRNSINKYNSRSIETSKVIEELIQLAKDIKQEQQRGNELGLNSDEIAFLRCFSFT
>NZ_AP014944.1|WP_001015193.1|65614_65836_+|hypothetical-protein
MNHETTHSDWRTVANCLASQNYISIVKGLVHHFTAIEDEEILDKIYEDFMNNGSITTVLNNDLQDIINYYLSK
>NZ_AP014944.1|WP_060829143.1|78367_81625_+|DEAD/DEAH-box-helicase-family-protein
MELKLIDNKGDNTLENLISEKVTKHSKISIQTAAFSIFAFHALQKEIKRSKGLRLVLTKSFFEKEETSFLKRYEIAQSEEDISGNKYEIKLRNKMNTAFIARETARLIEEKVKVHQLGPNQNALDELLIENEADIEGNVVVPSMFKFTSDGLGLTESNNVSSMTGIIGEPNHLAGLKDDFDAVWKDPKKSKEVTGKVLEKVRTIYQENPPEWIYFVSLYHIFHDKLSELDEQDIAPEGSGFKDSVIWNKLYQFQKDGVMGLIRKLEKYNGEILADSVGLGKTFSALAVIKYFELQRKRVLVLAPKRLRDNWTLYTRPDVRNVLVDDYFNYTVLNHTDLSRYKGESDGIKLDTFLWSDFDLVVIDESHNFRNNDTSVNRETKTRYQRLMEDIIQKGRKTKVLMLSATPINNRMNDLKNQIGFITEGKTDALAKYGVDDIDTTLRLAQQAFNQWMELDESERTTQSFLDKVNPDYFKLLDMLTIARSRKHIEKYYDTTSLGDFPERLKPMTVKPNIDASGQFPDLQDVYDSIGYLNMAMYQPLQYVLSTKRKRYEELYDTKVKEGKSSFRQVDREQALAKLIRANLFKRLESSIYSFGSTLDRMVGGIEDILKKIKEHQAGNVEMPSITDFDDEDLESAFDEQAVGTKTKILIGDMDLVKWSQALNEDLETLKELQTVTHRVTPEKDDKLMDLEKILKHKYEHPINGNNKKVIIFTAFADTANYLYENLADKVKRLCGLNSALVTGGSTPNKTTMKGVAVNDMSDILTNFSPISKGRDQINPNATEEIDLLIATDTISEGQNLQDADYLINYDIHWNPVRVIQRFGRIDRIGSRNKQIQLVNFWPNVDLDTYLNLEQRVKGRMVMLNTAATGEDDLLNIKSNKEMNDLKYRKKQLEQLQTQVIDLEDVNGAISITDMTFNDFKADLQNALKEHEKLLNEAPLGMYAITDTTNFPEAEPGVILTLKQQTNDLGQENSILPYIVVYMRMDGTVKINYMYAKQVLDFFKKLTVGKKTVNQPLVDEFYEETNGGKDMSAYSEILSKAIEAIRGKQDEVGMGSLFSPGGTSVQTELLDDLDDVELISFLIIR
>NZ_AP014944.1|WP_060829144.1|81625_82348_+|DUF4391-domain-containing-protein
MSELESKDIIKWWKFPSATIINRNLPKTQIYPHMKNTADKQFLQDSVQSIYMLASLKTDNTHIAVYEDDKELYQEIQFLYVKTKDKGDSTKIYKMLSHLIPYPLVILTDEPDSFTIYMGRFEKLSTGFLKLVNVYPSPVYQDENLEEVLQQISLIDLPRQNLKTFYDGLRDEIATATAKSQYGEAVGNITGEEKDQLDALKKQIEDLRGQIKKERQLNRKIDMQMKLKKLKDELLSKINQ
>NZ_AP014944.1|WP_060829145.1|82383_84384_+|site-specific-DNA-methyltransferase
MTNKRTNERLEEVSSHSLDITEQNIEKLKELFPEVLTEKKIDFDKLRLILGDEVETAPERYSFTWNGKKQAMQLAQQPTVATLKPNKAKSKNWDETQNLYIEGDNLEVLKILQKSYANKVKLIYLDPPYNTGSDFVYQDSFSDSIKNYLEVTGQVDEDGTKFSTNAETSGRYHTNWLNMMYSRLKLGRSLLTDDGVMFISIDEHEISNLEKLVSELFGENNLAGTIIWDKRNPKGDSKGVAMQHEYVIVVAKSLEIFSSKNEFKRLKKNAEGMLRKAKQIINKIGADFTLSDANDEYRKWVNAQDSFSGGERAYSKIDEQGNVYREVSMTWPNNKQAPADYFVPIIHPTTGKPTKIPGKGWRYPSATLKQMILDNMVVFGKDETTIPRRKYLLSENMYENVPSLYYNGKSGSTDVSNLEMKTTYFDNPKPVDLLKQIIQSTTTENDIILDFFSGSATTAESVMKQNSEDDNNRQFIMVQLPEIIEDKKSDGYKDGFRNIPEIAEERIRRAGDKIIGENPELADKLDIGFKVFELSKSNIKKWNAEPKDLNEQFELLANNFEEGSKSIDVVYEIMLKQGLDLTYPISEIKVGDAVVYDIAFGAMFVVLGDKITSEVASHIIKQIADEEAENSVVVLQDEKFINDSEKLNTIEQLNASGIQYNDILSI
>NZ_AP014944.1|WP_060829146.1|84404_87395_+|DEAD/DEAH-box-helicase-family-protein
MKIQFDTLDYQTDAVNSAVRVFEGQTIKESNFTITDDYSKGSMFTEDGIGVGNRVIINEEQMLKNVNKTQILDGIVPSDNLFGNNKAFPQFNIEMETGTGKTFVYLKTILELNKQYGFLKFVIVVPSIAIKEGVLKSFEITKDYFKNQYNGVVYDLFMFDSSKLDRVRSFASANTIDIMVTTIQSFNKDTNVMNRENDRISGARPIDLIAETRPIVIIDEPQSVDNTDLAKDALKSLDPSAGFRYSATHRDNTYPKIYQLGAVDAYDNQLVKQIEVAGIEMDEDGNRAHLKLIDVKTGKNGISAKIEVYKKTRNDADKITMNFKAGDDMFSKTKLQAYDEVGFIQDIDATPGFESVTFSGNPEKITLESATLEDEAIKRAQISKTIEEHLNKELKFKQSGQRIKVLSLFFLDKVENYRVYDEEGNPSLGRYARIFEEEYERLIHLSKYKELNDVNMPVSEVHDGYFSADNKGKLKNTKGDTQADESTYEMIMKNKEGLLTFYDEEKHHTAKANKIRFIFSHSALKEGWDNPNVFQIATLIETKDTINKRQKIGRGLRIAVNEDGERVPGFAVNTLTVMANESYKDFAEGLQKEYEEDGVIFGVFNKDSFATIITHYDEVTEEMEILGKEKSEQLFNYLKQEEFINSSGRATDKLKQAITDQEIEVPEGFIDVVPQILVAAKSKVKSLDIKDAKDKVEVKVVKEALADDFLELWNKIKYKTTYKIHFDSNKLIEFAAKGNESFDGVDSIQTRKGTYLYKKGMVEMSQAGVKADESSESGVRATTSGAYKLPDIITFLQNETSLTRKTIVAILQSVNNLDSFKNNPLSYMNQAAKIINAIKNQLIVDGIEYTRTNDEYEQTLFSTETLNAYLGEKGNSVKVDESKQKTVYDYVVTDSNIEKDFARKAEMDDNVKFYIKLPDWFKIRTPLGPYNPDWALLYEEDDEQHLYFIVETKGDTSFEQLRPHERAKILAGEKHFKAVDTDIKFKRVSDEAEIRG
>NZ_AP014944.1|WP_082704387.1|89969_90965_-|helix-turn-helix-transcriptional-regulator
MDEESIHKIIQLVEENLLENYSLDDYVQMTGYSKFHLMRIFKKAKGYTFYNYILNRRIAHASHYLLYTDMNIIDIAFMLNFQSQEAFSRSFKAVYGLLPGKYRKLLSGISQTSEAEVDITTEDIKGWIISGTAPQMYEIKLDSREYHSGKQSASIASIREASSYNENTFGTLMQSISSQDYKSKRLKFSAFVKTEAADRCGVWARVDDATSDVLQFDNMMERAIIGTNDWNYYSVVLDVNEMAESLHFGVLLIGKGKVWIDQFKIEEVNLSVPSTDIINKQQNLPAKPINLNSEDDSSAQNYFVKDCKILYRSPILSPNSQIYLLDRTFFL
>NZ_AP014944.1|WP_060829148.1|91254_94266_+|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein
MYENKREKHAIRKFSVGTASIVIGGLIYGFMGDNEAQASETSFNNLGENKVEFNAQNPQAPQQTYTEVTIKENQTSESKALENRNSQPEEKAKVEVVENEQPKIKSSVEENTVTDAQRQAVAKNEESSSEAIQQPKKEATDVEPQKKLSRAIQSATNIEQDVRAKKVNKEATRDVSKEVIVDNGEITGFKNGNNIHPHHGQGGRLNYKLKFPENVKSGDTFKIQLSDNVNTHGISVERNAPNIVTKNEQGREETIAEGNVLEDGRTILYTFKDYVNGKQNLTADLSISYFTSPENVKDSGPQLIESKIGIDVTSSDIYIYYDNSHYVDGRISELDKKEGKFKQIAYINPNGYLNGRGIISVSGDVVSGKPKASTTPKVSIYKYKGQGYPPASIYLEPNMWEEVIMNNNLINYNNNGSYSLSLDIANDQKYAIKYEGLFDSDAEKLLYRTYIQGYYNGYYPFSFEKINGVKLYENNASGSGELKPVPPKPNPEVHNNLVETTEDSNVIDISWDTALDEENGENKGPQEEITENNNVEVVEESNLIENTEDTAPDEENGENRGPQEEVTENKDVEVMEEHNLIENNENTMTEEESGQNEGSQEEVEEHQVIDIIADTTPEGESGQNEGSEEEIEENQITDIIEDTTPEGERGQNEGSQEEVEEHQVIDIIEDTTPEGESGRNEGNQEEVEEHQVIDIIADTTPEGERGQNEGSQEEVEEHQVIDILEDTTPEGESGQNEGNQEEIEENQITDIIEDTTPEGESGQNEGSQEEVEENQVIDIIEDTTPEGESGQNEGSQEEVEENQIIDIIEDTTPEGESGQNGGNQEEVEEHQIIDIIEDTTPEGESGQNGGNQEEIEEHQIIDIIADTTPEGESGQNEGNQEEIEEHQIIDIIEDTTPEGESGQNEGNQEEIEEHQVIDRVGGKAPERKGGQIERNQEKIEEHPINAPVIHVSTSMHKNANSKSVKVLPSTGEAHKNTPTLAILLTVIGSVLLFRRKSKFNKAK
>NZ_AP014944.1|WP_060829149.1|94664_95495_+|AraC-family-transcriptional-regulator
MEKYRVVSSERTHLFKDMHFLFAGEEYCKAGYRFGPAVRPNYIIHYIISGTGYYEFNGQVYKLSANQSFVIFPDKSSVYWADEADPWHYIWIGFTGVSSDEAIQQMGISVTFPIINFKKHNRCQEIVLKVLDNQTTSISAHFLFQSVLFDFLNEILLSRLSISKPQTAPEYSRYIHESLQYIENNYNHPFTISEMAEALFVNRSYLSRIFHQELGITLKEYINNFRITRARELLVITDYSYSEIAHQIGYESYNSFYKAFRHVTGETPSTYRSKQK
>NZ_AP014944.1|WP_060829150.1|95496_97713_-|alpha-galactosidase
MSIYINQDLLQFHLTNGQISYIFYIGPTHQPVQLYTGPHIEDANYTFLEHQQSRPVSNYMIENDTTFSHEHTLMEYPSFGSTDFRSPAFEVRHPDGSHITNLEYEHYEVRHQAPVLKDLPHVRQSQQNVETLIIYLIDPVSQLRVKLYYSLFDDMNIIARHTEFENTGVNTLTLTRALSMNLDLMSDNFSLVHLSGAWGRERHVTQQSLSPGTFEIQSLRGHSSHLHHPFFALAQPNTTEDSGLVYGMSFAYSGNFLGHVEVDNFNKTRASIGIHPEYFSWQLTPGTQFTTPQAYLTIGLAGFNDMSQQFHRLVHTYLIAPQWRNQPRPILINNWEATYYDFTEDKLVAIAEKAKEIGIEMFVLDDGWFGSRNSDHEGLGDFFVNETKLPKGLQHLNQRINDLGLDFGLWMEPEMVNKQSKLYAAHPDWVIQTPSRTMSHGRYQFVLDYTNPDVIDYVYHEISNILDHTNIKYIKWDMNRSMTEVFSSRWPTEQQGEIYHRYILGLYDLLHRITTRFPHILIESCASGGGRFDLGMLYYTPQIWTSDNTDAYQRQWIQYGTSYLYPTSTMGTHVSKSPNEQEHRSMPLATRANVSYFGTFGYELDLATLDATTLEIMKQQVTFMKTHRNLLQFGKFFRLLNPSQHEFTAWMVIDHNRNHAIVGVYKHLNTINNGRHRVVLKGLNPSAHYHISELNLTMAGNALMAIGIDIPDTSNGELRNGEAKTYDFDSWLYTLERV
>NZ_AP014944.1|WP_060829151.1|99830_100811_-|tRNA-dihydrouridine-synthase
MKENFWRELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTASFCHPEGIHSVRGRLTFSEDEQPMVAHIWGDQPEQFREMSIGLAEMGFKGIDLNMGCPVANVAQKGKGSGLILRPEVAAEIIQSTKAGGLPVSVKTRLGYYEIDEWKDWLKHVLKQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPDTLLTINGDIPDRQTGLELVEKYGVDGIMIGRGVFHNPFAFEKEPREHTSKELLDLLRLHLTLFQKYNKDEDRQFKSLRRFFKIYVRDIKGASQLRHQLMNTESIAEARELLDAFETQMENRTLT
>NZ_AP014944.1|WP_169925607.1|101200_101374_+|hypothetical-protein
MKTCRELYAELEYWDQYQPNNVSSSILKQAMRNQIKSQIRDQIDVSKNKDTILKITN

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Crispr_ID: NZ_AP014944_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014944_3

200142-200218

Orphan

Consensus_repeat	Method
CAGCTTTGTTGTCATCTTTGTGCATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014944_3

>merge|NZ_AP014944|3|200142-200218|CRISPRCasFinder
CAGCTTTGTTGTCATCTTTGTGCATGCCTTTATCTTCAGCTTTTTTGTCTTCAGCTTTGTTGTCATCTTTCTGCATG

>NZ_AP014944|3|3|200142-200218|CRISPRCasFinder
CAGCTTTGTTGTCATCTTTGTGCATG	CCTTTATCTTCAGCTTTTTTGTCTT
CAGCTTTGTTGTCATCTTTCTGCATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014944.1\|WP_060829221.1\|202144_202858_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_AP014944.1\|WP_060829214.1\|193872_195105_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341154
NZ_AP014944.1\|WP_060829215.1\|195247_195826_-\|DUF2812-domain-containing-protein	unknown	unknown	gnl\|CDD\|378589
NZ_AP014944.1\|WP_060829216.1\|195812_196139_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367559
NZ_AP014944.1\|WP_060829223.1\|203834_205265_-\|arginine-ornithine-antiporter	unknown	unknown	gnl\|CDD\|163522
NZ_AP014944.1\|WP_060829225.1\|206427_207663_-\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
NZ_AP014944.1\|WP_060829227.1\|208665_209259_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_AP014944.1\|WP_060829222.1\|202876_203818_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_AP014944.1\|WP_060829224.1\|205384_206392_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179366
NZ_AP014944.1\|WP_103356157.1\|197678_198158_-\|YagU-family-protein	unknown	unknown	gnl\|CDD\|226008
NZ_AP014944.1\|WP_060829212.1\|191740_192322_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341135
NZ_AP014944.1\|WP_060829213.1\|192323_193880_+\|type-I-restriction-modification-system-subunit-M	unknown	unknown	gnl\|CDD\|211578
NZ_AP014944.1\|WP_060829228.1\|209453_211229_+\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
NZ_AP014944.1\|WP_060829209.1\|188085_188274_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_060829219.1\|198503_199514_+\|DUF418-domain-containing-protein	unknown	unknown	gnl\|CDD\|225193
NZ_AP014944.1\|WP_060829226.1\|208088_208568_+\|ArgR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224355
NZ_AP014944.1\|WP_060829211.1\|188862_191658_+\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NZ_AP014944.1\|WP_060829230.1\|212501_213269_+\|serine-protease	unknown	unknown	gnl\|CDD\|226119
NZ_AP014944.1\|WP_060829229.1\|211488_212076_+\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|224565
NZ_AP014944.1\|WP_060829217.1\|196515_196842_+\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609

Protein	Function_ID	Function_description	E-value
NZ_AP014944.1\|WP_060829221.1\|202144_202858_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.80805e-29
NZ_AP014944.1\|WP_060829214.1\|193872_195105_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341154	cd17265, RMtype1_S_Eco4255III-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Escherichia coli O118:H16 07-4255 S subunit (S.Eco4255III) TRD2-CR2 and Escherichia coli ECONIH1 S subunit (S.EcoNIH1II) TRD2-CR2. Escherichia coli O118:H16 07-4255 S subunit (S.Eco4255III) recognizes 5'... GAGNNNNNGTTY ... 3', and Escherichia coli ECONIH1 S subunit (S.EcoNIH1II) recognizes 5'... YTCANNNNNNGTTY ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.Eco4255III-TRD1 recognizes GAG/CTC and S.EcoNIH1II-TRD1 recognizes YTCA/TGAR, while both S.EcoNIH1II-TRD2 and S.Eco4255III-TRD2 recognize RAAC/GTTY. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	4.46493e-47
NZ_AP014944.1\|WP_060829215.1\|195247_195826_-\|DUF2812-domain-containing-protein	gnl\|CDD\|378589	pfam11193, DUF2812, Protein of unknown function (DUF2812). This is a bacterial family of uncharacterized proteins, however some members of this family are annotated as membrane proteins.	8.36634e-22
NZ_AP014944.1\|WP_060829216.1\|195812_196139_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	4.92523e-09
NZ_AP014944.1\|WP_060829223.1\|203834_205265_-\|arginine-ornithine-antiporter	gnl\|CDD\|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_AP014944.1\|WP_060829225.1\|206427_207663_-\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_AP014944.1\|WP_060829227.1\|208665_209259_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.62492e-11
NZ_AP014944.1\|WP_060829222.1\|202876_203818_-\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	3.38057e-168
NZ_AP014944.1\|WP_060829224.1\|205384_206392_-\|ornithine-carbamoyltransferase	gnl\|CDD\|179366	PRK02102, PRK02102, ornithine carbamoyltransferase; Validated.	0
NZ_AP014944.1\|WP_103356157.1\|197678_198158_-\|YagU-family-protein	gnl\|CDD\|226008	COG3477, COG3477, Predicted periplasmic/secreted protein [Function unknown].	2.32556e-77
NZ_AP014944.1\|WP_060829212.1\|191740_192322_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341135	cd17246, RMtype1_S_SonII-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Shewanella oneidensis MR-1 S subunit (S.SonII) TRD2-CR2. This model contains Shewanella oneidensis MR-1 S subunit (S.SonII) TRD2-CR2 and similar TRD-CR's. S.SonII recognizes 5'... GTCANNNNNNRTCA ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases. S.SonII TRD1-CR1 does not belong to this subfamily.	1.46819e-08
NZ_AP014944.1\|WP_060829213.1\|192323_193880_+\|type-I-restriction-modification-system-subunit-M	gnl\|CDD\|211578	TIGR00497, hsdM, type I restriction system adenine methylase (hsdM). Function: methylation of specific adenine residues; required for both restriction and modification activities. The ECOR124/3 I enzyme recognizes 5'GAA(N7)RTCG. for E.coli see (J. Mol. Biol. 257: 960-969 (1996)). [DNA metabolism, Restriction/modification].	1.78758e-143
NZ_AP014944.1\|WP_060829228.1\|209453_211229_+\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
NZ_AP014944.1\|WP_060829230.1\|212501_213269_+\|serine-protease	gnl\|CDD\|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	2.56591e-32
NZ_AP014944.1\|WP_060829219.1\|198503_199514_+\|DUF418-domain-containing-protein	gnl\|CDD\|225193	COG2311, COG2311, Predicted membrane protein [Function unknown].	3.15429e-39
NZ_AP014944.1\|WP_060829226.1\|208088_208568_+\|ArgR-family-transcriptional-regulator	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	1.07731e-37
NZ_AP014944.1\|WP_060829211.1\|188862_191658_+\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	0
NZ_AP014944.1\|WP_060829229.1\|211488_212076_+\|DsbA-family-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	3.50707e-15
NZ_AP014944.1\|WP_060829217.1\|196515_196842_+\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.95137e-23

>NZ_AP014944.1|WP_060829219.1|198503_199514_+|DUF418-domain-containing-protein
MEPTKKRIELLDYMRGFALLGIIFANIIPILKIQGFHGQIDIDYMKYLNILVEAKFFSIFSLLFGIGFYIFFNSAKCKDVNPYFLYLRRILFLLLLGIIHQIFQPGEALLFYAIIGLPLLLFTFVNKKLNLVIGLALLFVALFGGNKIAFVPGLFILGYTIGQFDLHKNIYNRPKSLIVALLLSFGGFIISMVVLHQHNVLPTYELAKSQISLNAYVEKYNTFSDLIVFTAPFISLFYVLLLTYLLQYDTVKKILLPLKYYGQMALTNYLMNTLLIIVAGQFLTLTFAQTGIACLVILIVQMIFSMIWLRFFIYGPIEYIWRAATYLQFFSIKRSQ
>NZ_AP014944.1|WP_103356157.1|197678_198158_-|YagU-family-protein
MGLLFYTGIIGGLLSGIVKLGWEVMFPPRTPERNATNPPQQLLQQLGFSHDFTHQTYTFSGMSLPWVSFIVHFSFSIVIAIIYCFLVKKYAYMAMGQGAVFGIVIWVLFHLMIMPIMHTVPAPWDQPFQEHLSELFGHIVWMMTIDLVRQLFVHRYQLD
>NZ_AP014944.1|WP_060829217.1|196515_196842_+|PadR-family-transcriptional-regulator
MSVSNQMMKGLLDGAILGLIAQGETYGYEILEKLKANQFPEISDGSIYPVLLRLSKRGYVHTTTRKSDNGGPKRKYYTISESGKQELEQFKAKWRDLNTGMNHLFGRV
>NZ_AP014944.1|WP_060829216.1|195812_196139_-|helix-turn-helix-transcriptional-regulator
MKRYPLVPLSETMHYILLAVRTPIHGYKIMQIVKEKSEGEVNIAAGTLYGALENLKKHQYIELISPPIERKKVYQITELGEHILAIENKRLLRMAEIYQEGSDKNEEV
>NZ_AP014944.1|WP_060829215.1|195247_195826_-|DUF2812-domain-containing-protein
MRKFKIFMNPIKEEAWINAQLEKGYQLISHSSWGVYTFRKTEKKYVTRIDYRSLNKKQYDEYIALHEDCGWQHVYGHKYGTDNQYWQKEKEGQDVLFSDITSQIHYFKRLQTFYLSILLPFFFIIFFYLKSGIFHLFLTPGLFDMPFDLMWKAILFELPFALLRLLPLLVLIYIGRLIIKNSIKIKAMEKNT
>NZ_AP014944.1|WP_060829214.1|193872_195105_+|restriction-endonuclease-subunit-S
MTNETKNIPELRFPEFEGEWDEKELGDIGEKVKTKNKFEKFDETFTNSAEQGIVSQKEYFEKDISNSKNLSNYYVVENNDFVYNPRISNYAPVGPINRNKLKRTGIMSPLYTIFKMRKVDYTFCEYFFSSTKWHNFMKFNGDSGARSDRFSIKDSIFFKMPIKVPTNLEQQKIGDFFSKLDRQIELEEKKLALLEEQKKGYMQQIFSQELRFKDENGNNYPEWETLKVKDIAETFRGLTYKPEDIRTEGVRVLRSSNIIKDKIHFYEDDIFVDERVVKIPLVDEDDILITAANGSPKLVGKHAIIEKLKDKSVAGGFMYILRSNYSKFMQIWMSTTEYRRIISRVQGGNGSIGNLSRNDLENGNITLPCNEEKSKIGNFFKKIDELIERQYTKIELLKKRKQGLLQKMFV
>NZ_AP014944.1|WP_060829213.1|192323_193880_+|type-I-restriction-modification-system-subunit-M
MSITEKQRQQQAELQKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKTEVQVDVLLEGENMTYEQAWQNEDYKEALEAELLERIGYVIEPQDLFSTLIKKIENQTFEIEDLHKAISKIETSTRGQESEDDFDHLFDDMDLNSSRLGNTNAARTKLISKVMMNLSTLPFVHSDIEIDMLGDAYEYLIGQFAATAGKKAGEFYTPQQVSKILAKIVTANKQDLKNVYDPTCGSGSLLLRVGREANVRHYYGQEYNSTTFNLARMNMLLHDVNYSHFSIENGDTLEHPAVLEEKFEAVVANPPYSAKWSADPSFLDDERFSNYGKLAPKSKADFAFIQHMIYHLDDNGTMAVVLPHGVLFRGAAEGVIRKYLIEEKNYLDAIIGLPANLFFGTSIPTAILVFKKCREKDENVLFIDASQSFEKGKNQNHLSDEDVNKIVETYLKREDIEKYSHVAILDEIKENDYNLNIPRYVDTFEEEEPVDLEAVQQEIKAVDEEIASLEKEIAGYLKQLGVELHD
>NZ_AP014944.1|WP_060829212.1|191740_192322_+|restriction-endonuclease-subunit-S
MSAIKPLIRYHSGTIINRLTPVTDALGSPIMIYDQNMMDEDLGKYTWHPTQPKMITLEEGHNAKCIEAGQIVFNMITGECVIVSSKYSGAILPYNYTHIEVDRESVYPRYLVYWLNHSPKALKQIKLYQQGGSMIKKMTHKQLQALEIPLPRMHQQELIGNLAHSRVRLKYLKAKREHLMDTYLRAILFREEH
>NZ_AP014944.1|WP_060829211.1|188862_191658_+|type-I-restriction-endonuclease-subunit-R
MAYQSEFALENDVLKQLTQMGYEQLNIHTHDEMLQNFRAIINERHIEALNHQPLTDTEFDCLITDINGKSVFDSAVILRDKYVLKRDDETVVYLSFLDQNKWCQNKFQVTNQVSVKDTYKSRYDVTILINGLPLVQIELKRSGVAISEAFNQVERYRKQNFTGLFRYIQLFVISNKMETRYYANSDLTILKSHMFYWSNEKNERINHLKHFIEDFLEPCHLAKIISRYMIVNETDKILMALRPYQVYAVEKLIERALETNNNGFIWHTTGSGKTLTSFKASQILSQQEGIKKVIFLVDRKDLDSQTLAEFNKFQEDSVDLTDSTRKLLKQLGDATLPLIVTTIQKMAHAIKSNDPVMNQYEHDKVVFIIDECHRSQFGEMHRSVKQHFKNAQYFGFTGTPRFEENKSQDGRATADIFDKCLHHYLIKDAIRDGNVLGFSVDYARTFDPKKDLEEEYVSKINEKEVWMAEERISKITDHIIENYAKKTRNGHYTSMLTVQSIPMAIAYYEAFKKAKEAGKHNLNVTTIFTFQPNEDSNEQEDFVHSREMLDRVMVDYNAMFGTNFNTDYFDGFFSDVSKKMKKVIPGEKIDILIVVDMFLTGFDSKKLNTLYVDKNLKYHNLIQAYSRTNRVEKETKPYGNIVCYRDLKVETDQAIEIFSQTDNTDTVLSGSYEEYLADFKEILKQLFALVITPADVDQLEREDDQKEFVLIFRALASLLLKLKTFEEFEFTPEQLGISEQTFEDYKSKYLNLYEKVVKSNKEESEGVSILEDIDFKVEILRNDLINVQYIMNLIGQIELKDKVEQERNRKQIHQLLDRADDEQLRLKADLIRQFLDKVVPTLKEGTDVNEAYYQYEEAEKHKEIEAFAEDKAYPSQLLGHIIEEYEYSGSINKNTIDEGLKNQGGFLARTKTANKIKSFVMETAQKYSSTE
>NZ_AP014944.1|WP_060829209.1|188085_188274_+|hypothetical-protein
MKKIYNIITTILILISLTIIVTSIFVHNEQYQTMINTALFILVIFIGIFAVTVRIIHDKTKR
>NZ_AP014944.1|WP_060829221.1|202144_202858_-|Crp/Fnr-family-transcriptional-regulator
MGQNPYDHSTIDNSLIKKNVNAYLEQFANFINIPTVALQPYKNEFIVRQYNKGQVIYYSSDELTHLYYLIDGYILREHYSVNGDVYRVLNKGEHLYPLHNLFQDKTTNEMCTALTDSIVMAVPIELIEYICRNHDKVFIQMYKYLCENEKQLTEYNMALSAKSAKARVEKVLIYLCHTIGEDHEEFYEIKQFLTIQMVSDLASVSRETTGHIVNELKTQNLLLKDQKNWMISKAILK
>NZ_AP014944.1|WP_060829222.1|202876_203818_-|carbamate-kinase
MYKKIVIALGGNAIQTTDGSAETQKQAIRTTMQRLKPLFNTDYDIVISHGNGPQIGSLLIQQATADSPQTPAMPLDVCGAMTQGMIGFWIETEVNRVLAEVNSDRKAGTVITRVEIDENDPRMSNPTKPIGPFYTEAQVEQQKAQYPDSIYKEDAGRGYRKVVPSPLPVSILEHELISTLVENNNIIVACGGGGVPVVKRGDTYEGVEAVIDKDFASERLAQLIDANTLMILTNVENVYINFNEPNQEKLTDIDVESLKRYAQEGKFAEGSMLPKIEAAIDFVENGEGRRAVITNLDKAYEAFKGEVGTQIYK
>NZ_AP014944.1|WP_060829223.1|203834_205265_-|arginine-ornithine-antiporter
MGGTDENKLNKTALIGLVIGSMIGGGAFNIISDMGKEAGGLAIIIGWLITAVGMISLAFVFQNLTNERQDLDGGIYSYAQAGFGDFIGFSSAWGYWFAAFLGNVAYATLLMSAVGNFFPMFKGGNTLPSIIIASILLWGVHYLILKGVETAALINSIVTIAKLIPILLVLVCMIVAFNFDTFKAGIFGMTSGPTHMFSWGDTLSQVKSTMLVTVWVFTGIEGAVVFSGRAKNKKDVGSATVIGLVSVLVIYFLMTVLAQGVIQQNHISELSNPSMAAVLEHIVGHWGSVLVNIGLIISVLGAWLGWTLLAGELPFIVAKDGLFPKWFAKENENKAPVHSLLVTNILVQIFLISMLFTQSAYQFAFSLASSAILVPYMLSAFYQVKYTIQTKHRATTKQWMIGIIASVYTIWLVYAAGLDYFLLTMLLYIPGLIVYTIVQRNNQKPLKRVDYLFFVIIIILAIIGILRLLSGAVDVF
>NZ_AP014944.1|WP_060829224.1|205384_206392_-|ornithine-carbamoyltransferase
MTDIQKPLDLKGRHLLKEDDFTKKEFSDLIDFAMTLKSYKQQGIPHRYLEGKNIALLFEKTSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQDTVEALAAFSGVPVWNGLTDAWHPTQMLADYMTIKENFGHLDGIKLTYVGDGRNNVANSLLVAGPMLGVDVTICSPKSLFPSQDYIDIAERRAKQDGGSVTITDNIDEGVKGADVIYTDVWVSMGEESEFESRIKLLKDYQVNKALFDKTGKDSTIFLHCLPAFHDTNTEYGQKIKDEYGLSEMEVTDEIFRSKHAKVFDQAENRMHTIKAVMAATLG
>NZ_AP014944.1|WP_060829225.1|206427_207663_-|arginine-deiminase
MEKGPIQVNSEIGRLKTVLLKRPGKELENLVPDHLSGLLFDDIPYLKVAQEEHDKFAQVLRDEGVEVVYLEKLAAEAIADKAVREQFIDDILAESQKTVLGHEKEIKTLFETLSDQELIDKIMSGVRKEEIQLETNHLVEYMDDRYPFYLDPMPNLYFTRDPQASIGRGMTINRMYWRARRRESIFMTYILKHHPRFKDADVPVWLDRNSPFNIEGGDELVLSKEVLAIGISERTSAQAIERLARQILFDDQSTFTKVLAIEIPNSRSFMHLDTVFTMIDYDKFTMHAAIFKEENHMNIFTIEKDEATNDIKISHSSQLKATLEDALHVDNIEFIPTGNGDVIDGAREQWNDGSNTLTIRPGVVVTYDRNYVSNQLLRDKGVKVIEITGSELVRGRGGPRCMSQPLFREDI
>NZ_AP014944.1|WP_060829226.1|208088_208568_+|ArgR-family-transcriptional-regulator
MKKRKRLDLVSMIVKEHDIHSKAEIVDYIEKHFGIRYSVATISRDLNELKIYKMPSAHQERCYQKYNENAQNDAKAKLINFYKDEIASVVIKDTYLIIKTAPGFAQSINYYIDQMELNEVLGTVGGNDTILVLTASAELSKYVHYKLFNQTYQDANVTP
>NZ_AP014944.1|WP_060829227.1|208665_209259_-|TetR/AcrR-family-transcriptional-regulator
MNKQDLRVIKTQNALMNAFTELLKVKEFEHITIQDLCDYALIRRSTFYRHYKDKYHLLNHAIENVLNRFRQIHLSDIRFEDPKPFLERYIHDLLTFINDNKVIVNSVVTHHLYDETSRIIYEQIYQAINKQTQYDIQTGARLDVDPTIYNHFLTGGVLSVVFNWSKEAHAEQTLTAVKKDIVNLICGMRETHLKRIN
>NZ_AP014944.1|WP_060829228.1|209453_211229_+|oleate-hydratase
MYYSKGNYEAFARPRKPENVENKSAYLVGSGLAALAAACFLIRDGQMKGSQVHVLEELPKPGGSLDGDELPNKGYVVRGGREMENHFECLWDLFRSVPSLEVENASVLDEFYWLNKEDPNYSRCRMIENRGHRVDTDGDFTLTQKAIKEILDLCLTNEEDLNDVKITDVFSEDFLKSNFWVYWKTMFAFEPWHSAMEMRRYLMRFVHHIGGLADFSALKFTKYNQYESLVLPMVEYLKSNDVQFEYNIKVEDIKVDVTTSQKLAREILIKRDGKNDVIPLTSNDLVFVTNGSITESSTYGDNDTPAPITDDIGGSWLLWNNLAKQSPEFGNPEKFYKDLPKRSWFISATATTSNKKIIGAIERLCKRDPLSHKTVTGGIITVNDSSWQMSFTVNRQQQFKSQPDDQVSTWIYALYSDVDGDYIKKPITECSGSEICQEWLYHMGVPTEEIEYLATEEANTIPAYLPYITSYFMPRAVGDRPLVVPHQSRNLAFIGNFAETERDTVFTTEYSVRTAMEAVYQLLDIDRGVPEVIASVFDLRVLMDAAYELNDRKSLQEITESSKIQKVALSGFLRKIKGTYVETLLKNHHLL
>NZ_AP014944.1|WP_060829229.1|211488_212076_+|DsbA-family-protein
MKKIFYFLMMALVLVAFTACQKGEHREKQVKIVEYFDYKCPYCKVFDQKVMTEIEKKYGTERIDYQLIDVAFLGNDAIEGARAAKAVQIVAPQQFMTFHHHLIEQQPNHEGKWLTHDKIDQQINRLSISKKQKDKIKNEYKSKNSEAWKRAEKDIIKANNEKIKLVPTLKINGEEVSDPLNKDEVFKKIDDALKA
>NZ_AP014944.1|WP_060829230.1|212501_213269_+|serine-protease
MNKFLLKTATVVSLSFMAFTQVSYASSHVDYKIIGEDSRVKVNNTTLNPYQSITFIESKFNNVYEDCSGTVIAPNKVITAAHCVYNPEHGGLTEQSKLTPGLNGKIAPFGQFESNDIKVPQQYKDHQEDQYDIAIIDVKPRNGVSIGNVVKPIQIEASDNSKNKEVEITGYPSDKFEQLRVQTQWSSSSLVDFQDGNKAYYTADTISGESGAPIFNKQTNNIIGVHTGAVETNAGLYNRGTTFTKSILNWVKQNL

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Crispr_ID: NZ_AP014944_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014944_4

1549038-1550061

orTypeII

Consensus_repeat	Method
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CRISPRCasFinder
GTTTCATTTATACCTAAAATTACAGAGTACTAAAACNNNNNN	CRT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAACCT	PILER-CR
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	PILER-CR

15 spacers

cas2,cas1,cas9

The CRISPR arrays of NZ_AP014944_4

>merge|NZ_AP014944|4|1549038-1550061|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GATTAGTATTCATTTAAAATTGCAGAGTACTAAAACCTTCCGAATCCATTTCAGCGCAATAAACAGTTTCATTTATACCTAAAATTACAGAGTACTAAAACGATTGATAGTTTGCGATTCTTGCAGTCATTGTTTCATTTATACCTAAAATTACAGAGTACTAAAACACTCACTTGTAAATTCCTCCACTTGCTCTAGTTTCATTTATACCTAAAATTACAGAGTACTAAAACTCGTCATCAATCCATCGCCATATGCTTCTTGTTTCATTTATACCTAAAATTACAGAGTACTAAAACTGACAACCACGCTTTTAGCTTGCATATCAAGTTTCATTTATACCTAAAATTACAGAGTACTAAAACATATTCTATTCAATTCGTTCTGCAACTTGTGTTTCATTTATACCTAAAATTACAGAGTACTAAAACTTACATAATCGTTTATGATTATTTCATGTTGTTTCATTTATACCTAAAATTACAGAGTACTAAAACCTGGAATAACCACAAAGCCAGAGTCAGTTTGTTTCATTTATACCTAAAATTACAGAGTACTAAAACCCATGATGTCTAAAAACACCGATTTACCATGTTTCATTTATACCTAAAATTACAGAGTACTAAAACACGTTAGATTTGCAGGTGTTAAGCACGGCTGTTTCATTTATACCTAAAATTACAGAGTACTAAAACTGTATGGGGTGCGGTCGACTCTACTATCAGTTTCATTTATACCTAAAATTACAGAGTACTAAAACGTAAATAATTCCGTTTGGACTCGTTACGTTGTTTCATTTATACCTAAAATTACAGAGTACTAAAACCCATCGCTTCTTTGCGTGAATTTGAAATATGTTTCATTTATACCTAAAATTACAGAGTACTAAAACATGTTTTTTCATTAAAGCTACCAGTAATTCGTTTCATTTATACCTAAAATTACAGAGTACTAAAACAATTCGCCTTTATATTCAGGTTTCTTTTTTGTTTCATTTATACCTAAAATTACAGAGTACTAAAAC

>NZ_AP014944|4|4|1549038-1550061|CRISPRCasFinder
GATTAGTATTCATTTAAAATTGCAGAGTACTAAAAC	CTTCCGAATCCATTTCAGCGCAATAAACA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	GATTGATAGTTTGCGATTCTTGCAGTCATT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ACTCACTTGTAAATTCCTCCACTTGCTCTA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TCGTCATCAATCCATCGCCATATGCTTCTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TGACAACCACGCTTTTAGCTTGCATATCAA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ATATTCTATTCAATTCGTTCTGCAACTTGT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TTACATAATCGTTTATGATTATTTCATGTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CTGGAATAACCACAAAGCCAGAGTCAGTTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CCATGATGTCTAAAAACACCGATTTACCAT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ACGTTAGATTTGCAGGTGTTAAGCACGGCT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TGTATGGGGTGCGGTCGACTCTACTATCA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	GTAAATAATTCCGTTTGGACTCGTTACGTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CCATCGCTTCTTTGCGTGAATTTGAAATAT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ATGTTTTTTCATTAAAGCTACCAGTAATTC
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	AATTCGCCTTTATATTCAGGTTTCTTTTTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC

>NZ_AP014944|4|3|1549044-1550061|CRT
TATTCATTTAAAATTGCAGAGTACTAAAACCTTCCG	AATCCATTTCAGCGCAATAAACA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	GATTGATAGTTTGCGATTCTTGCAGTCATT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ACTCACTTGTAAATTCCTCCACTTGCTCTA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TCGTCATCAATCCATCGCCATATGCTTCTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TGACAACCACGCTTTTAGCTTGCATATCAA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ATATTCTATTCAATTCGTTCTGCAACTTGT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TTACATAATCGTTTATGATTATTTCATGTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CTGGAATAACCACAAAGCCAGAGTCAGTTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CCATGATGTCTAAAAACACCGATTTACCAT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ACGTTAGATTTGCAGGTGTTAAGCACGGCT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TGTATGGGGTGCGGTCGACTCTACTATCA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	GTAAATAATTCCGTTTGGACTCGTTACGTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CCATCGCTTCTTTGCGTGAATTTGAAATAT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ATGTTTTTTCATTAAAGCTACCAGTAATTC
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	AATTCGCCTTTATATTCAGGTTTCTTTTTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC

>NZ_AP014944|4|2|1549052-1549207|PILER-CR
TAAAATTGCAGAGTACTAAAACCTTCCGAATCCATTTCA	GCGCAATAAACAGTTTCATTTATACCT
AAAATTACAGAGTACTAAAACGATTGATAGTTTGCGATT	CTTGCAGTCATTGTTTCATTTATACCTAAA
ATTACAGAGTACTAAAACACTCACTTGTAAATTCCTCCACTTGCTCTAGTTTCATTTATACCTAAAATTACAGAGTACTAAAACTCGTCATCAATCCATCGCCATATGCTTCTTGTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TGACAACCACGCTTTTAGCTTGCATATCAA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ATATTCTATTCAATTCGTTCTGCAACTTGT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TTACATAATCGTTTATGATTATTTCATGTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CTGGAATAACCACAAAGCCAGAGTCAGTTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CCATGATGTCTAAAAACACCGATTTACCAT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ACGTTAGATTTGCAGGTGTTAAGCACGGCT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TGTATGGGGTGCGGTCGACTCTACTATCA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	GTAAATAATTCCGTTTGGACTCGTTACGTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CCATCGCTTCTTTGCGTGAATTTGAAATAT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ATGTTTTTTCATTAAAGCTACCAGTAATTC
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	AATTCGCCTTTATATTCAGGTTTCTTTTTT


>NZ_AP014944|4|3|1549301-1550061|PILER-CR
	GCGCAATAAACAGTTTCATTTATACCT
AAAATTACAGAGTACTAAAACGATTGATAGTTTGCGATT	CTTGCAGTCATTGTTTCATTTATACCTAAA
ATTACAGAGTACTAAAACACTCACTTGTAAATTCCTCCACTTGCTCTAGTTTCATTTATACCTAAAATTACAGAGTACTAAAACTCGTCATCAATCCATCGCCATATGCTTCTTGTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TGACAACCACGCTTTTAGCTTGCATATCAA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ATATTCTATTCAATTCGTTCTGCAACTTGT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TTACATAATCGTTTATGATTATTTCATGTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CTGGAATAACCACAAAGCCAGAGTCAGTTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CCATGATGTCTAAAAACACCGATTTACCAT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ACGTTAGATTTGCAGGTGTTAAGCACGGCT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	TGTATGGGGTGCGGTCGACTCTACTATCA
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	GTAAATAATTCCGTTTGGACTCGTTACGTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	CCATCGCTTCTTTGCGTGAATTTGAAATAT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	ATGTTTTTTCATTAAAGCTACCAGTAATTC
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC	AATTCGCCTTTATATTCAGGTTTCTTTTTT
GTTTCATTTATACCTAAAATTACAGAGTACTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014944.1\|WP_060829983.1\|1561772_1562744_+\|thermonuclease-family-protein	unknown	unknown	gnl\|CDD\|366169
NZ_AP014944.1\|WP_060829982.1\|1560645_1560909_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_060829978.1\|1556211_1557582_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NZ_AP014944.1\|WP_060829972.1\|1546079_1546673_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_060829974.1\|1550235_1551246_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_060829980.1\|1559239_1559446_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_016424977.1\|1558593_1559103_-\|thermonuclease-family-protein	unknown	unknown	gnl\|CDD\|366169
NZ_AP014944.1\|WP_050331066.1\|1547183_1547546_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|130944
NZ_AP014944.1\|WP_060829977.1\|1552473_1555650_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187774
NZ_AP014944.1\|WP_060829975.1\|1551258_1551567_-\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_AP014944.1\|WP_060829965.1\|1537909_1539364_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|223903
NZ_AP014944.1\|WP_060829967.1\|1540083_1540890_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_AP014944.1\|WP_060829970.1\|1543212_1544496_-\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NZ_AP014944.1\|WP_060829969.1\|1542142_1543207_-\|threonine-synthase	unknown	unknown	gnl\|CDD\|236013
NZ_AP014944.1\|WP_060829968.1\|1541225_1542146_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_AP014944.1\|WP_060829971.1\|1544687_1546040_+\|aspartate-kinase	unknown	unknown	gnl\|CDD\|236364
NZ_AP014944.1\|WP_060829966.1\|1539595_1539910_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_060829973.1\|1547734_1548586_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014944.1\|WP_082704415.1\|1557584_1558313_-\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|224982
NZ_AP014944.1\|WP_060829976.1\|1551571_1552474_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851

Protein	Function_ID	Function_description	E-value
NZ_AP014944.1\|WP_060829976.1\|1551571_1552474_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.78216e-99
NZ_AP014944.1\|WP_016424977.1\|1558593_1559103_-\|thermonuclease-family-protein	gnl\|CDD\|366169	pfam00565, SNase, Staphylococcal nuclease homolog. Present in all three domains of cellular life. Four copies in the transcriptional coactivator p100: these, however, appear to lack the active site residues of Staphylococcal nuclease. Positions 14 (Asp-21), 34 (Arg-35), 39 (Asp-40), 42 (Glu-43) and 110 (Arg-87) [SNase numbering in parentheses] are thought to be involved in substrate-binding and catalysis.	2.01568e-45
NZ_AP014944.1\|WP_050331066.1\|1547183_1547546_+\|hypothetical-protein	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.46711e-08
NZ_AP014944.1\|WP_060829977.1\|1552473_1555650_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	6.68632e-119
NZ_AP014944.1\|WP_060829975.1\|1551258_1551567_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	6.37732e-27
NZ_AP014944.1\|WP_060829965.1\|1537909_1539364_+\|amino-acid-permease	gnl\|CDD\|223903	COG0833, LysP, Amino acid transporters [Amino acid transport and metabolism].	0
NZ_AP014944.1\|WP_060829967.1\|1540083_1540890_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	6.81529e-74
NZ_AP014944.1\|WP_060829970.1\|1543212_1544496_-\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NZ_AP014944.1\|WP_060829969.1\|1542142_1543207_-\|threonine-synthase	gnl\|CDD\|236013	PRK07409, PRK07409, threonine synthase; Validated.	0
NZ_AP014944.1\|WP_060829968.1\|1541225_1542146_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	1.19484e-111
NZ_AP014944.1\|WP_060829971.1\|1544687_1546040_+\|aspartate-kinase	gnl\|CDD\|236364	PRK09034, PRK09034, aspartate kinase; Reviewed.	0
NZ_AP014944.1\|WP_060829978.1\|1556211_1557582_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	4.1633e-29
NZ_AP014944.1\|WP_082704415.1\|1557584_1558313_-\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|224982	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only].	6.81579e-83
NZ_AP014944.1\|WP_060829983.1\|1561772_1562744_+\|thermonuclease-family-protein	gnl\|CDD\|366169	pfam00565, SNase, Staphylococcal nuclease homolog. Present in all three domains of cellular life. Four copies in the transcriptional coactivator p100: these, however, appear to lack the active site residues of Staphylococcal nuclease. Positions 14 (Asp-21), 34 (Arg-35), 39 (Asp-40), 42 (Glu-43) and 110 (Arg-87) [SNase numbering in parentheses] are thought to be involved in substrate-binding and catalysis.	7.38439e-39

>NZ_AP014944.1|WP_060829973.1|1547734_1548586_+|hypothetical-protein
MSIMIWVIISALFIIVLLSLLRVKFYQNKLEVELYTKSQLLNKISKMKQEKYQFQTKEKDSSEYHLDLRRAKQTLTQDLDALVDDEKIRHYRIFTTSQIAPKNTIYPFISQFDILVVTNIGLILLNLKALKAKTFYHFEGRLPLKDESDIHQIVGHYIAHQYHNQFQSELRTHYTFSENIHENEVTYQFNKFDPYEMAEKATQNLQTHFESLVDVPVSTIGVIYCAKQNGERIDGDATPYSQVYTCENNQDFKNALQQFIATTHSNLSDASYEQVINNIEHNN
>NZ_AP014944.1|WP_050331066.1|1547183_1547546_+|hypothetical-protein
MNNHFKMETEAIFFYESNRKKIISELKKQHGLKLNDILFLYHLKTTNSRRISLHKVKQSIDFSLMEIHKSLTALTEKDIIGKERSTEDERKVFITIDDKQAKKMDQLLDDFNQIQKEVLQ
>NZ_AP014944.1|WP_060829972.1|1546079_1546673_-|hypothetical-protein
MEENQKCHVNQLMYTLIERVPNDFKFHGEAATNLFLNDQLCLEDGIEICVNRMDLLTVLSVIPQNYRIKGLDKHGKMLNCEKHRLHQIASVEVYENEILLLNIIVYDVYNEEWMFRLNNNIRIPEKQIYYHSLKWNVDYIKPEIVLMYILHEPLNQKQVQYYRHLIDRMSYYQFITLKVAVGEDLLRKVLTERSTYR
>NZ_AP014944.1|WP_060829971.1|1544687_1546040_+|aspartate-kinase
MKVSKFGGSSVASAEQIKKVLNIVNSDNDRRIIVVSAPGKRNDDDIKTTDLLIRLYEKVVNGLDYIHKKEEILTRFQDIIDGLSLKTDVLNEIDQTLEHHISTLKDQPARLLDALKSSGENFNAQIIAAYNNEKGIPTTYLSPKEAGIIVTDDPGNAQILESSYDQINQLKNYDKKIIIPGFFGYSETNHIVTFPRGGSDITGAIVARGVKADLYENFTDVSGIYRANPKVISKPEIINEITYREMRELSYAGFSVFHDEALQPLYHYRIPVVIKNTNRPDDPGTYIVHDREIDRKNVVTGISCDKNFTSINIKKYLMNRQVGFTVNILDILAKHHISFDHMPSGIDNISIIMRSAQLVGKEQKVLEEIRQRCEIDELSVENDLAILMVVGEGMSAAVGTANKITDALAQANINLKMINQGSSEISMMFGISTKDADDAVKACYQHCYQK
>NZ_AP014944.1|WP_060829970.1|1543212_1544496_-|homoserine-dehydrogenase
MKQLNVALLGLGTVGSGVVKIIEENHQQIKDTIQKDIHIKHILVRDTSKKRPLNISRYHLTEDINDILNDNDVDIIIEVMGGIEPTVDWLKAALTQKKHVITANKDLLAVHLRVLEDLAQQNAVALKYEASVAGGIPIVNAINNGLNANNISKFMGVFNGTSNFILTKMTEEGTPYEDALKEAQDLGFAEADPTDDVEGIDAARKVVITSYLSFNQVINLKDVETEGISGVTTQDIDAAKALGYKIKLIGKGAYVNGKVEASVKPTLIAHSHQLAAVENEYNAIYVIGDAVGETMFYGKGAGSLATGSAVVSDLLNVALQFESDLHTLPPHFELKTDKTKEMMDDGETVTIKEKESYYLVINTPEVSQKQVEATLKSKLPFHKSLQIETLSSNSVAVVVVGVDQHPTTYVESEEGYHVQKVYPVEGV
>NZ_AP014944.1|WP_060829969.1|1542142_1543207_-|threonine-synthase
MKLWKGLVEEYQSFLPVTDDTPKVTLNEGHTPLIYCDTISEMLGVELYVKYEGANPTGSFKDRGMVMAVTKAKEQGRKIVICASTGNTSASAAAYAARAGLKAIVVIPEGKIALGKLSQAVMYGAEIVSIEGNFDEALEIVKEVAQDGEIELVNSVNPYRIEGQKTGAFEIVDQLEGQAPDVLAIPVGNAGNITAYWKGFKTYHDANQSELPQMFGFQAEGASPIVQNKVVKNPETIATAIRIGNPASWDKAVQAIDESNGLIDAVTDEEILEAYQLMTSKEGIFSEPASNASIAGLIKLHRQGRLKQGQRVVAVLTGNGLKDPDTAIGLLENPIQALPNNKESIIQYIKDALQ
>NZ_AP014944.1|WP_060829968.1|1541225_1542146_-|homoserine-kinase
MTKNKLSLKVPASTANLGCGFDSIGMALNKFLYIEAQIISGEKWRFVHEGPHLVGLPGDEAHYMYQIAQKVADKYRVTLPALEIKMFSDIPLARGLGSSASALVAALYIANYFGDIELSKYELLQLATNIEGHPDNVAPTIYGGLVVGYHNEETHITSVAHIDVPDVDFIVTIPSYELATTTARKVLPETLTHKEAVKYSAISNTMISALIQHNYVLAGQMMEQDGLHEPFRQHLIQDFDQIKTIAHRYHAYATVLSGAGPTILTMVKKENSGPLVRALRKEIKSCHSELATVNTTGVVSDVIHHY
>NZ_AP014944.1|WP_060829967.1|1540083_1540890_-|Cof-type-HAD-IIB-family-hydrolase
MKIELIVMDMDDTLMTSENHLSEKTKSYLLNLQNEGYKLALASGRPTEGMLPIAKELKMDQYGSYIMSYNGAQTTDLAANEIVSKKDIEKEEFDKIVDFCRERNLFVLTYDHGKIIYDGEHEYMNRESELTGLEMEKVDDLKSYIQKSVPKVMGVDFEENIEKIIKQFGNEFNKAIDMTTSKPFFLEFMRKSVSKGAAIEALAERLDIDVNHIVAFGDSANDIEMFKTAGTAIAMDNASDEVKEQADMVTKSNDEDGIPYALEQLINK
>NZ_AP014944.1|WP_060829966.1|1539595_1539910_+|hypothetical-protein
MVGQTNLFDDVLKPDERFVIVVQALENKNGQLAKRTLREYSSLTHDQMNNLFQHLKELYLDSEFEANQSAFTITDYTNLDYTADQVYAHIKRHRGKHEWTHTAK
>NZ_AP014944.1|WP_060829965.1|1537909_1539364_+|amino-acid-permease
MEEKKLSRTLQSRHITMIAIGGAIGTGLFVATGGVIAQAGPGGAILAYIIIGIMLYFLMSSIGEMATFYPVSGAFSSYATRFVDPSLGFTMGWLYWTIWSLVTSVDVIVASNVISYWDTFHFFSPLVWSLLFLTLLFLVNVFTVKAFGEAEFWLSLIKVITIIIFIILGILMIFGILGGHYYGLKNFTVGEAPFVGGISGFLSVLLIAGFSVGGTEVVAVTAGESDNPRESMPKAIKQVFWRILLFYVLSIAVISAILAYTDPTLLNENGSIAQSPFTIVFDKVGIAFAASVINAVILTSLLSAANSGVFTTSRMLYSLSQHGQAPQFLGKIHHRSKLPLNALFTTFVFIAIVTLYANYNPKSVIGLLNIIGALVTFVWGSSLIAQIRMRRAIKKQNKNIDQLLAYKAPFFPVGPIIVIAILLFLIFGSSAEAIVHFEVSKLLQSFLPIIVLIVVYFVHKAINKTKVIPLEEIDLSEHESYRES
>NZ_AP014944.1|WP_060829974.1|1550235_1551246_-|hypothetical-protein
MNNMIWEIKSTLIPKTEMNIGMYTSIYNEFETKEEDILNIICDYFQKRHSNKDEVSIYERINQEQLPYTLYQCYMLSHEEINKEHTLSANALITKKINRLLSEQYERESYLNSINVLLEDLLNLVKSDLPLKTKRFDIKSFIKNIEFAYDLDHEYSRLIVRLESLIPLIVEELNYQSNNKTLLIYCYPESNLSPKEQIRFRNILEGLGVPIIVLTGSKHFIAHDLAHMNYIRNEKQLLTAEFIDHLVWDAPLNFEKHEIKRSLEKIIQLYQEVIELTPKISNYNLADIIVFEPIDIYVVVRYLKHAKQDFELDIHYDNLPIAVAKYIKMYDLKFNK
>NZ_AP014944.1|WP_060829975.1|1551258_1551567_-|CRISPR-associated-endonuclease-Cas2
MRVMIMFDLPVETKKQRRIYSKFRKRLLENGFLMMQYSVYIKSVANKDAADFSVLQVKQFLPQDGHVRSLIITEKQYEKMQILLGKEDQNIALLGDNRTIIF
>NZ_AP014944.1|WP_060829976.1|1551571_1552474_-|type-II-CRISPR-associated-endonuclease-Cas1
MSWRIVYASDVTKLSLSLNSLKIAKGDQEIKVPLSDIFAVVIEDLTVTVTARLLVELSDYNILVIFCNQKHLPECVLQPISGHFSQYAQMKAQLSWDELSKEELWKQIVKQKILNQITCMEHNNIDEARIRKMHELRDVVQLKDEHNIEGQAAKYYFNSFFEEFRRDDDNSLENAVLNYGYTILNAAIARTIVAKGLIPALGIHHIGGRNHFNLASDFIEPFRPLVDLFLFKHPPEDFLTKAYRLKLVNLLHARVLIDGKMQTVIRAIEIMIQSIIDYFREGQKQLLKFPDIKQFTFYEL
>NZ_AP014944.1|WP_060829977.1|1552473_1555650_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKNSYILGLDVGIASVGYGLIHSDSKSVIDAGVRLFPEANVENNEGRRAKRGSRRLKRRRIHRLDRVKYLLAQYHLIIDDKIPKSTNPYAIRVKGLSSALSKSELVIALLHLAKRRGIHNVNVVMDENESTNELSTKEQLKENAKQLENRYVCELQLDRLNEQYKVRGERNRFKTEDFVREARQILTTQQKYHDIDEHFIEQYTHLLETRREYYEGPGKGSQYGWEGDLKQWYEMLMGRCTYFPEELRSVKYAYTADLFNALNDLNNLVIARDENEKLEYFEKYHIIENVFKQKKSPTLKQIAKEIDVKESDIKGYRITKNGKPQFTSFKLYHDLNKIFLDKKNLENIELLDEIAFILTLYQDPLSIKEALDQLQDLLTESEKEAIAHLNGYTGTHRLSLKCLHLLIDEMWQTSRNQMEVFTALNLKPQKYQLSKQKQIPKKMVEEFILSPVVKRSFIQSIEIVNTIIKKYGLPEEIIIELAREKNSEDRRKFLNRIQKENENTRKQVEEVIREYGNRNAKGLVEKIKLHQMQEGKCLYSLQNIPLDDLLRNPSHYEIDHIIPRSVSFDNSFNNKVLVKQEENSKKGNRTPYQYLNSNESVLSYVQFKQHILNLSKSKERISKKKREYLLEERDINKFEVQKEFINRNLVDTRYATRELVQLLKSYFSANDLDVKVKTINGSFTNYLRKAWKFDKSRNKGFKHHAEDALIIANVSYLFKQSKELKEANAILENNNLSLNKNKDSKNLLTEQDYRKMFEIPKQVQDIKDYKDFKYSHRVDKKPNRQLINDSLYSTREVNENHYIVQTVKDIYAKDNTKIKDLFLKTPEKLLMYQHDPQTFEKLMLVIKQYGEEKNPFAKYYEENGEYLTKYAKNEKGPTIKRLKYIGKKVGTHLDISTNFSGAKRKVVQLSIKPFRFDVFHSKAGYHMLTLTYMDIKKKEKHYQILKNEYQALKERYKVPSDAQFIGSFYYNDLISINDELFRVIGVNNSTRNVVELNMVDINYKDYCDLMGIKKTPRIFKTITKKTGKIEKYSTDILGNQFKVKPSKSPQLIFKRGVL
>NZ_AP014944.1|WP_060829978.1|1556211_1557582_-|APC-family-permease
MKKLGFWSIVLLAINSIIGSGIFLSPGAVISIAGSYTPYVYILAAIFASILAVTFAAASKYVNKSGAAYAYATAAFGNNIGFYVGITRFIAACIAWGVMSTAVVKTVITIFGGDNTNTTLITIGFLILMVTLLLINITGNKLFEIINNLSTIGKLLALVTTIVAGIVVIVTTGEVRFSEVTHIVDTSKIDTTTFVLAIVAAFYAFTGFESVASGSEDMKNPEKNLPRAIPLAILSIAAVYLGIILVTMALNPQALIETKQVVSLVAVFHSPIIQNIILYGALISMFGINVAASFSTPRIIEAIANQQQISPWFKKRTKYDFPFNAFIVTFLIAIIIPMAFQYNMTSIIVLSSISRFIQFLVVPIGVIVFYYNKNKGTVLENVKKNVFTDVILPTISFLFTIILLVKFNWKGQFSIVEGQHTTLNYFAITAMVIGYIVLPAILFILNKMRYQQSDIK
>NZ_AP014944.1|WP_082704415.1|1557584_1558313_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MVAIIGITANILRDKDGMFPGYERCYINQDYVYSVTKHAGVPVVLPIHSDKNAIVKQVEQLDGLILSGGYDVSPHLYGEDPRNLIGETLLKRDLFEYTALEQAKKRGIPILGICRGAQLINVYHGGTLYQDVSYRERETLRHWQGVNPTEKTHRIQILEQCHLARVFEEREIFVNSFHHQLIKDIAPDFKGTARSSDGVIECIEAQNYPYLVGVQWHPEMLWREEAMDKLFIDFIKNAKESG
>NZ_AP014944.1|WP_016424977.1|1558593_1559103_-|thermonuclease-family-protein
MKKFTSGLLIVVVAIFVLTLQYVNGQGPFKTTEGSTKGDSYIVTRVIDGDTIIVNKDGKEERVRMIGVDTPETVKPNTPVQPYGKEASDFTKKHLTGKRVTLEYDRAPKDRYGRTLAYVWVGDKMFNVRLAKEGLARAKFYSPNYKYRPQIEQAQKEAQKKKLNIWSEA
>NZ_AP014944.1|WP_060829980.1|1559239_1559446_+|hypothetical-protein
MKTFKNNYLSLVVIIVAILIGFFLQHKFNLPLFAGAFIGVFLGMLGGFITQILMPKDQNHDADQKHRQ
>NZ_AP014944.1|WP_060829982.1|1560645_1560909_+|hypothetical-protein
MGELNKNELEQLEKRINHRFDDLERHLHALPMHLEDKMKLIFQIEKEILRGERIKDRDKIINRIAVTLTVIGTILTTIIALFTFFWR
>NZ_AP014944.1|WP_060829983.1|1561772_1562744_+|thermonuclease-family-protein
MKQRQWYQTQWFTILMLIFVFPVGLFLMWKYQSWGKWIKIIITVVVLIIFMINFQNNKQPQDSHSTKQETTQEHANKEEHKKQTSKHKDEKNEAKKEKEDKESYEPGTTDRIPVKLSAAVDGDTAKFVYNNKTETFRFLLIDTPETKHPRLGKQPFGQEASDRTAELLRNAKKIEVEFDVGQKQDKYQRYLAYIYVDGKMLNDILVKEGLARVAYVYPPNTRYLSELEASQEKAREEKLGIWSLTSAFEEESHEQPATTPAPAKNDNTAQPAPQQSQTEPAQSTQSFANCTQLRTVYPNGVPQGHPAYQPKLDRDNDNFACER

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP014944_4	4.2\|1549139\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549139-1549168	30	MK075001	Staphylococcus phage phiSP15-1, complete genome	6522-6551	1	0.967
NZ_AP014944_4	4.2\|1549139\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549139-1549168	30	MK075006	Staphylococcus phage phiSP119-3, complete genome	10234-10263	1	0.967
NZ_AP014944_4	4.3\|1549205\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549205-1549234	30	MT423824	Staphylococcus virus pSp_SNUABM-S, complete genome	22879-22908	1	0.967
NZ_AP014944_4	4.3\|1549205\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549205-1549234	30	MT423823	Staphylococcus virus pSp_SNUABM-J, complete genome	23635-23664	1	0.967
NZ_AP014944_4	4.3\|1549205\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549205-1549234	30	MT724048	Staphylococcus phage SAP3, partial genome	3322-3351	1	0.967
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	KX827371	Staphylococcus phage SpT99F3, complete genome	19597-19619	1	0.957
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	MK075002	Staphylococcus phage phiSP38-1, complete genome	21634-21656	1	0.957
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	MK075002	Staphylococcus phage phiSP38-1, complete genome	21634-21660	1	0.963
NZ_AP014944_4	4.18\|1549157\|30\|NZ_AP014944\|PILER-CR	1549157-1549186	30	MK075001	Staphylococcus phage phiSP15-1, complete genome	6522-6551	1	0.967
NZ_AP014944_4	4.18\|1549157\|30\|NZ_AP014944\|PILER-CR	1549157-1549186	30	MK075006	Staphylococcus phage phiSP119-3, complete genome	10234-10263	1	0.967
NZ_AP014944_1	1.14\|67821\|35\|NZ_AP014944\|CRISPRCasFinder,CRT	67821-67855	35	MT926124	Staphylococcus phage vB_SauP_EBHT, complete genome	2846-2880	2	0.943
NZ_AP014944_1	1.14\|67821\|35\|NZ_AP014944\|CRISPRCasFinder,CRT	67821-67855	35	MK922548	Staphylococcus phage SA46-CTH4, complete genome	3204-3238	2	0.943
NZ_AP014944_1	1.14\|67821\|35\|NZ_AP014944\|CRISPRCasFinder,CRT	67821-67855	35	MK922547	Staphylococcus phage SA30-CTH2, complete genome	3197-3231	2	0.943
NZ_AP014944_1	1.14\|67821\|35\|NZ_AP014944\|CRISPRCasFinder,CRT	67821-67855	35	KJ210330	Staphylococcus phage GRCS, complete genome	3491-3525	2	0.943
NZ_AP014944_1	1.14\|67821\|35\|NZ_AP014944\|CRISPRCasFinder,CRT	67821-67855	35	MK936475	Staphylococcus phage SA03-CTH2, complete genome	14280-14314	2	0.943
NZ_AP014944_1	1.15\|67892\|33\|NZ_AP014944\|CRISPRCasFinder,CRT	67892-67924	33	NC_013373	Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence	26794-26826	2	0.939
NZ_AP014944_1	1.26\|67891\|34\|NZ_AP014944\|PILER-CR	67891-67924	34	NC_013373	Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence	26794-26827	2	0.941
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	MG592473	Vibrio phage 1.101.O._10N.261.45.C6, partial genome	117358-117382	2	0.92
NZ_AP014944_4	4.1\|1549074\|29\|NZ_AP014944\|CRISPRCasFinder	1549074-1549102	29	KX827371	Staphylococcus phage SpT99F3, complete genome	19597-19625	2	0.931
NZ_AP014944_4	4.1\|1549074\|29\|NZ_AP014944\|CRISPRCasFinder	1549074-1549102	29	MK075002	Staphylococcus phage phiSP38-1, complete genome	21634-21662	2	0.931
NZ_AP014944_4	4.3\|1549205\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549205-1549234	30	AP019561	Staphylococcus phage SP197 DNA, complete genome	7626-7655	2	0.933
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	KY389064	Staphylococcus phage phi879, complete genome	16674-16696	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	KY389063	Staphylococcus phage phi575, complete genome	18299-18321	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NZ_CP046030	Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence	40793-40815	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	AF424783	Staphylococcus aureus phage phi 13, complete genome	18336-18358	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	AB044554	Staphylococcus prophage phiPV83 proviral DNA, complete sequence	18068-18090	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	GQ915271	Staphylococcus phage SAP090B, partial sequence	3714-3736	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NC_004617	Staphylococcus prophage phi 13, complete genome	18336-18358	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	KY653125	Staphylococcus phage IME1346_01, complete genome	18318-18340	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NC_021773	Staphylococcus phage JS01, complete genome	29707-29729	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	MH401414	Staphylococcus aureus phage SA45ruMSSAST97, complete genome	29706-29728	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	MH401415	Staphylococcus aureus phage SA537ruMSSAST97, complete genome	29707-29729	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	KX232515	Staphylococcus phage 3 AJ-2017, complete genome	24537-24559	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NC_009761	Staphylococcus phage tp310-1, complete sequence	19144-19166	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	MG543995	Staphylococcus phage UPMK_1, partial genome	114646-114668	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	AB243556	Staphylococcus phage phiPVL108 DNA, complete genome	19598-19620	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NC_008689	Staphylococcus phage phiPVL108, complete genome	19598-19620	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	MH384260	Staphylococcus phage SA780ruMSSAST101, complete genome	19416-19438	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NC_048658	Staphylococcus phage SA7, complete genome	15492-15514	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NC_009763	Staphylococcus phage tp310-3, complete sequence	18419-18441	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NC_002321	Staphylococcus phage PVL proviral DNA, complete sequence	1319-1341	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	NC_002486	Staphylococcus prophage phiPV83, complete genome	18068-18090	2	0.913
NZ_AP014944_4	4.16\|1549080\|23\|NZ_AP014944\|CRT	1549080-1549102	23	FJ713816	Staphylococcus phage phiPVL-CN125, complete genome	20915-20937	2	0.913
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	KX827371	Staphylococcus phage SpT99F3, complete genome	19597-19623	2	0.926
NZ_AP014944_1	1.25\|67820\|36\|NZ_AP014944\|PILER-CR	67820-67855	36	MK936475	Staphylococcus phage SA03-CTH2, complete genome	14279-14314	3	0.917
NZ_AP014944_1	1.25\|67820\|36\|NZ_AP014944\|PILER-CR	67820-67855	36	MT926124	Staphylococcus phage vB_SauP_EBHT, complete genome	2846-2881	3	0.917
NZ_AP014944_1	1.25\|67820\|36\|NZ_AP014944\|PILER-CR	67820-67855	36	MK922548	Staphylococcus phage SA46-CTH4, complete genome	3204-3239	3	0.917
NZ_AP014944_1	1.25\|67820\|36\|NZ_AP014944\|PILER-CR	67820-67855	36	MK922547	Staphylococcus phage SA30-CTH2, complete genome	3197-3232	3	0.917
NZ_AP014944_1	1.25\|67820\|36\|NZ_AP014944\|PILER-CR	67820-67855	36	KJ210330	Staphylococcus phage GRCS, complete genome	3491-3526	3	0.917
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NC_003042	Clostridium perfringens str. 13 plasmid pCP13, complete sequence	24310-24334	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NC_023917	Clostridium perfringens plasmid pCP-OS1 DNA, complete sequence, strain: OS1	22117-22141	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NC_023918	Clostridium perfringens plasmid pCP-TS1 DNA, complete sequence, strain: TS1	22099-22123	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NZ_MK275619	Clostridium perfringens strain JXJA17 plasmid p1, complete sequence	55651-55675	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NZ_CP014218	Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence	22814-22838	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	KM236237	Citrobacter phage Miller, complete genome	152170-152194	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	KC801932	Escherichia phage Lw1, complete genome	150181-150205	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	MK448931	Streptococcus phage Javan414, complete genome	26482-26506	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NC_031057	Citrobacter phage vB_CfrM_CfP1, complete genome	153732-153756	3	0.88
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	28772-28796	3	0.88
NZ_AP014944_4	4.2\|1549139\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549139-1549168	30	MF417958	Uncultured Caudovirales phage clone 7F_13, partial genome	8672-8701	3	0.9
NZ_AP014944_4	4.9\|1549601\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549601-1549630	30	MK075001	Staphylococcus phage phiSP15-1, complete genome	10277-10306	3	0.9
NZ_AP014944_4	4.9\|1549601\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549601-1549630	30	MK075006	Staphylococcus phage phiSP119-3, complete genome	13986-14015	3	0.9
NZ_AP014944_4	4.18\|1549157\|30\|NZ_AP014944\|PILER-CR	1549157-1549186	30	MF417958	Uncultured Caudovirales phage clone 7F_13, partial genome	8672-8701	3	0.9
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	CP015514	Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence	591810-591834	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NZ_CP018877	Bacillus megaterium strain JX285 plasmid 4, complete sequence	48077-48101	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NZ_CP045273	Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence	651025-651049	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	MT366947	Bacillus phage Hyb2phi3Ts-SPbeta, complete genome	31527-31551	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	KY030782	Bacillus phage phi3T, complete genome	31527-31551	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NC_001884	Bacillus phage SPBc2, complete genome	42038-42062	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	AF020713	Bacteriophage SPBc2 complete genome	42038-42062	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	MT366946	Bacillus phage Hyb1phi3Ts-SPbeta, complete genome	34126-34150	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	MT366948	Bacillus phage Hyb3phi3Ts-SPbeta, complete genome	31527-31551	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	CP052843	Bacillus phage Hybphi3Ts, partial sequence	7970-7994	4	0.84
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	MT366945	Bacillus phage phi3Ts, complete genome	31527-31551	4	0.84
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	KX232515	Staphylococcus phage 3 AJ-2017, complete genome	24533-24559	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	AF424783	Staphylococcus aureus phage phi 13, complete genome	18336-18362	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	AB044554	Staphylococcus prophage phiPV83 proviral DNA, complete sequence	18068-18094	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	GQ915271	Staphylococcus phage SAP090B, partial sequence	3714-3740	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	NC_004617	Staphylococcus prophage phi 13, complete genome	18336-18362	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	KY389064	Staphylococcus phage phi879, complete genome	16674-16700	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	KY653125	Staphylococcus phage IME1346_01, complete genome	18318-18344	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	NC_021773	Staphylococcus phage JS01, complete genome	29707-29733	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	MH401414	Staphylococcus aureus phage SA45ruMSSAST97, complete genome	29706-29732	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	MH401415	Staphylococcus aureus phage SA537ruMSSAST97, complete genome	29707-29733	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	NC_009761	Staphylococcus phage tp310-1, complete sequence	19144-19170	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	MG543995	Staphylococcus phage UPMK_1, partial genome	114646-114672	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	KY389063	Staphylococcus phage phi575, complete genome	18299-18325	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	AB243556	Staphylococcus phage phiPVL108 DNA, complete genome	19598-19624	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	NC_008689	Staphylococcus phage phiPVL108, complete genome	19598-19624	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	MH384260	Staphylococcus phage SA780ruMSSAST101, complete genome	19416-19442	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	NC_048658	Staphylococcus phage SA7, complete genome	15492-15518	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	NC_009763	Staphylococcus phage tp310-3, complete sequence	18419-18445	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	NC_002321	Staphylococcus phage PVL proviral DNA, complete sequence	1319-1345	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	NC_002486	Staphylococcus prophage phiPV83, complete genome	18068-18094	4	0.852
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	FJ713816	Staphylococcus phage phiPVL-CN125, complete genome	20915-20941	4	0.852
NZ_AP014944_3	3.1\|200168\|25\|NZ_AP014944\|CRISPRCasFinder	200168-200192	25	NC_014533	Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence	58979-59003	5	0.8
NZ_AP014944_4	4.1\|1549074\|29\|NZ_AP014944\|CRISPRCasFinder	1549074-1549102	29	KY389064	Staphylococcus phage phi879, complete genome	16674-16702	5	0.828
NZ_AP014944_4	4.1\|1549074\|29\|NZ_AP014944\|CRISPRCasFinder	1549074-1549102	29	KY389063	Staphylococcus phage phi575, complete genome	18299-18327	5	0.828
NZ_AP014944_4	4.2\|1549139\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549139-1549168	30	NC_013378	Staphylococcus epidermidis plasmid SAP105B, complete sequence	2062-2091	5	0.833
NZ_AP014944_4	4.18\|1549157\|30\|NZ_AP014944\|PILER-CR	1549157-1549186	30	NC_013378	Staphylococcus epidermidis plasmid SAP105B, complete sequence	2062-2091	5	0.833
NZ_AP014944_1	1.16\|67961\|35\|NZ_AP014944\|CRISPRCasFinder,CRT	67961-67995	35	NZ_CP043848	Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence	50879-50913	6	0.829
NZ_AP014944_2	2.2\|76863\|41\|NZ_AP014944\|CRISPRCasFinder	76863-76903	41	MF417907	Uncultured Caudovirales phage clone 7F_7, partial genome	31442-31482	6	0.854
NZ_AP014944_2	2.2\|76863\|41\|NZ_AP014944\|CRISPRCasFinder	76863-76903	41	KY653129	Staphylococcus phage IME1365_01, complete genome	11951-11991	6	0.854
NZ_AP014944_4	4.12\|1549798\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549798-1549827	30	NZ_KX858825	Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence	10829-10858	6	0.8
NZ_AP014944_4	4.17\|1549091\|27\|NZ_AP014944\|PILER-CR	1549091-1549117	27	KY653118	Morganella phage IME1369_01, complete genome	9919-9945	6	0.778
NZ_AP014944_2	2.5\|76862\|42\|NZ_AP014944\|CRT	76862-76903	42	KY653129	Staphylococcus phage IME1365_01, complete genome	11951-11992	7	0.833
NZ_AP014944_2	2.5\|76862\|42\|NZ_AP014944\|CRT	76862-76903	42	MF417907	Uncultured Caudovirales phage clone 7F_7, partial genome	31441-31482	7	0.833
NZ_AP014944_4	4.1\|1549074\|29\|NZ_AP014944\|CRISPRCasFinder	1549074-1549102	29	KY653118	Morganella phage IME1369_01, complete genome	9917-9945	7	0.759
NZ_AP014944_4	4.10\|1549667\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549667-1549696	30	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17295-17324	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	MT758689	Lactobacillus phage Lbab1, complete genome	19746-19775	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NC_012530	Lactobacillus phage Lb338-1, complete genome	27043-27072	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NZ_CP022441	Klebsiella sp. LY plasmid unnamed3, complete sequence	302322-302351	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	KU318421	Klebsiella pneumoniae strain KP04 plasmid pKP04VIM, complete sequence	206284-206313	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NC_023911	Raoultella planticola strain KpNDM1 plasmid pKpNDM1, complete sequence	143078-143107	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NZ_CP025964	Klebsiella pneumoniae strain WCHKP34 plasmid pIMP4_LL34, complete sequence	75267-75296	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NZ_CP026019	Klebsiella pneumoniae strain 13190 plasmid p13190-1, complete sequence	159889-159918	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NZ_MF344566	Klebsiella pneumoniae strain A324 plasmid pA324-IMP, complete sequence	208012-208041	7	0.767
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NZ_MF344563	Klebsiella pneumoniae strain 13190 plasmid p13190-VIM, complete sequence	219501-219530	7	0.767
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	MN694790	Marine virus AFVG_250M551, complete genome	33981-34014	8	0.765
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NZ_LR214999	Mycoplasma conjunctivae strain NCTC10147 plasmid 3	55978-56011	8	0.765
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	LR214965	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11	45570-45603	8	0.765
NZ_AP014944_4	4.4\|1549271\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549271-1549300	30	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1935099-1935128	8	0.733
NZ_AP014944_4	4.15\|1549996\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549996-1550025	30	NZ_CP036543	Bacteroides fragilis strain DCMOUH0018B plasmid pBFO18_1, complete sequence	2079-2108	8	0.733
NZ_AP014944_4	4.15\|1549996\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549996-1550025	30	NZ_CP032274	Acinetobacter sp. WCHAc010034 plasmid p6_010034, complete sequence	999-1028	8	0.733
NZ_AP014944_4	4.15\|1549996\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549996-1550025	30	MT411892	Staphylococcus phage Metroid, complete genome	100635-100664	8	0.733
NZ_AP014944_4	4.15\|1549996\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549996-1550025	30	AP018375	Staphylococcus phage phiSA039 DNA, complete genome	92829-92858	8	0.733
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	123527-123560	9	0.735
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	MT150133	Enterobacteria phage vB_EcoM_IME540, complete genome	108313-108342	9	0.7
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NC_028925	Enterobacteria phage vB_EcoM_VR25, complete genome	61519-61548	9	0.7
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	MK234886	Escherichia phage AnYang, complete genome	30700-30729	9	0.7
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	MT446420	UNVERIFIED: Escherichia virus TH54, complete genome	121018-121047	9	0.7
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	KU878969	Escherichia phage MX01, complete genome	63189-63218	9	0.7
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	KY979109	Salmonella phage SHP1, complete genome	13917-13946	9	0.7
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	NC_019500	Enterobacteria phage Bp7, complete genome	5506-5535	9	0.7
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	MK295203	Escherichia phage vB_EcoM_005, complete genome	76903-76932	9	0.7
NZ_AP014944_4	4.14\|1549930\|30\|NZ_AP014944\|CRISPRCasFinder,CRT,PILER-CR	1549930-1549959	30	MH051913	Enterobacteria phage vB_EcoM_IME281, complete genome	110186-110215	9	0.7
NZ_AP014944_4	4.2\|1549139\|30\|NZ_AP014944\|CRISPRCasFinder,CRT	1549139-1549168	30	NZ_CP017759	Cupriavidus necator strain NH9 plasmid pENH92, complete sequence	28493-28522	10	0.667
NZ_AP014944_4	4.18\|1549157\|30\|NZ_AP014944\|PILER-CR	1549157-1549186	30	NZ_CP017759	Cupriavidus necator strain NH9 plasmid pENH92, complete sequence	28493-28522	10	0.667
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NZ_CP028886	Borrelia turcica IST7 plasmid lp32-A, complete sequence	1427-1460	11	0.676
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1264667-1264700	12	0.647
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1264689-1264722	12	0.647
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1264689-1264722	12	0.647
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1264689-1264722	12	0.647
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1264689-1264722	12	0.647
NZ_AP014944_1	1.5\|67173\|34\|NZ_AP014944\|CRISPRCasFinder,CRT	67173-67206	34	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1264689-1264722	12	0.647

1. spacer 4.2|1549139|30|NZ_AP014944|CRISPRCasFinder,CRT matches to MK075001 (Staphylococcus phage phiSP15-1, complete genome) position: , mismatch: 1, identity: 0.967

gattgatagtttgcgattcttgcagtcatt	CRISPR spacer
gattgatagtttgcgattcttgcaatcatt	Protospacer
************************.*****

2. spacer 4.2|1549139|30|NZ_AP014944|CRISPRCasFinder,CRT matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 1, identity: 0.967

gattgatagtttgcgattcttgcagtcatt	CRISPR spacer
gattgatagtttgcgattcttgcaatcatt	Protospacer
************************.*****

3. spacer 4.3|1549205|30|NZ_AP014944|CRISPRCasFinder,CRT matches to MT423824 (Staphylococcus virus pSp_SNUABM-S, complete genome) position: , mismatch: 1, identity: 0.967

actcacttgtaaattcctccacttgctcta	CRISPR spacer
actcacttgtaaattcctccacttgctgta	Protospacer
*************************** **

4. spacer 4.3|1549205|30|NZ_AP014944|CRISPRCasFinder,CRT matches to MT423823 (Staphylococcus virus pSp_SNUABM-J, complete genome) position: , mismatch: 1, identity: 0.967

actcacttgtaaattcctccacttgctcta	CRISPR spacer
actcacttgtaaattcctccacttgctgta	Protospacer
*************************** **

5. spacer 4.3|1549205|30|NZ_AP014944|CRISPRCasFinder,CRT matches to MT724048 (Staphylococcus phage SAP3, partial genome) position: , mismatch: 1, identity: 0.967

actcacttgtaaattcctccacttgctcta	CRISPR spacer
actcacttgtaaattcctccacttgctgta	Protospacer
*************************** **

6. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to KX827371 (Staphylococcus phage SpT99F3, complete genome) position: , mismatch: 1, identity: 0.957

aatccatttcagcgcaataaaca	CRISPR spacer
agtccatttcagcgcaataaaca	Protospacer
*.*********************

7. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to MK075002 (Staphylococcus phage phiSP38-1, complete genome) position: , mismatch: 1, identity: 0.957

aatccatttcagcgcaataaaca	CRISPR spacer
agtccatttcagcgcaataaaca	Protospacer
*.*********************

8. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to MK075002 (Staphylococcus phage phiSP38-1, complete genome) position: , mismatch: 1, identity: 0.963

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tccgagtccatttcagcgcaataaaca	Protospacer
*****.*********************

9. spacer 4.18|1549157|30|NZ_AP014944|PILER-CR matches to MK075001 (Staphylococcus phage phiSP15-1, complete genome) position: , mismatch: 1, identity: 0.967

gattgatagtttgcgattcttgcagtcatt	CRISPR spacer
gattgatagtttgcgattcttgcaatcatt	Protospacer
************************.*****

10. spacer 4.18|1549157|30|NZ_AP014944|PILER-CR matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 1, identity: 0.967

gattgatagtttgcgattcttgcagtcatt	CRISPR spacer
gattgatagtttgcgattcttgcaatcatt	Protospacer
************************.*****

11. spacer 1.14|67821|35|NZ_AP014944|CRISPRCasFinder,CRT matches to MT926124 (Staphylococcus phage vB_SauP_EBHT, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataaaaatatttttgg	Protospacer
********.*********************** **

12. spacer 1.14|67821|35|NZ_AP014944|CRISPRCasFinder,CRT matches to MK922548 (Staphylococcus phage SA46-CTH4, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataagaatattttagg	Protospacer
********.**************.***********

13. spacer 1.14|67821|35|NZ_AP014944|CRISPRCasFinder,CRT matches to MK922547 (Staphylococcus phage SA30-CTH2, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataagaatattttagg	Protospacer
********.**************.***********

14. spacer 1.14|67821|35|NZ_AP014944|CRISPRCasFinder,CRT matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataaaaatatttttgg	Protospacer
********.*********************** **

15. spacer 1.14|67821|35|NZ_AP014944|CRISPRCasFinder,CRT matches to MK936475 (Staphylococcus phage SA03-CTH2, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataagaatattttagg	Protospacer
********.**************.***********

16. spacer 1.15|67892|33|NZ_AP014944|CRISPRCasFinder,CRT matches to NC_013373 (Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence) position: , mismatch: 2, identity: 0.939

tcatctttcatgtcactgattaattcatttgta	CRISPR spacer
tcatctttcatatcattgattaattcatttgta	Protospacer
***********.***.*****************

17. spacer 1.26|67891|34|NZ_AP014944|PILER-CR matches to NC_013373 (Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence) position: , mismatch: 2, identity: 0.941

ctcatctttcatgtcactgattaattcatttgta	CRISPR spacer
ctcatctttcatatcattgattaattcatttgta	Protospacer
************.***.*****************

18. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to MG592473 (Vibrio phage 1.101.O._10N.261.45.C6, partial genome) position: , mismatch: 2, identity: 0.92

cctttatcttcagcttttttgtctt	CRISPR spacer
tctttatcttcagcttttttgtatt	Protospacer
.********************* **

19. spacer 4.1|1549074|29|NZ_AP014944|CRISPRCasFinder matches to KX827371 (Staphylococcus phage SpT99F3, complete genome) position: , mismatch: 2, identity: 0.931

cttccgaatccatttcagcgcaataaaca	CRISPR spacer
cttctgagtccatttcagcgcaataaaca	Protospacer
****.**.*********************

20. spacer 4.1|1549074|29|NZ_AP014944|CRISPRCasFinder matches to MK075002 (Staphylococcus phage phiSP38-1, complete genome) position: , mismatch: 2, identity: 0.931

cttccgaatccatttcagcgcaataaaca	CRISPR spacer
cctccgagtccatttcagcgcaataaaca	Protospacer
*.*****.*********************

21. spacer 4.3|1549205|30|NZ_AP014944|CRISPRCasFinder,CRT matches to AP019561 (Staphylococcus phage SP197 DNA, complete genome) position: , mismatch: 2, identity: 0.933

actcacttgtaaattcctccacttgctcta	CRISPR spacer
actcacttgtaaactcctccacttgttcta	Protospacer
*************.***********.****

22. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to KY389064 (Staphylococcus phage phi879, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
tatccatttcagcacaataaaca	Protospacer
 ************.*********

23. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to KY389063 (Staphylococcus phage phi575, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
tatccatttcagcacaataaaca	Protospacer
 ************.*********

24. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NZ_CP046030 (Staphylococcus chromogenes strain 1401 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

25. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to AF424783 (Staphylococcus aureus phage phi 13, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

26. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to AB044554 (Staphylococcus prophage phiPV83 proviral DNA, complete sequence) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

27. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to GQ915271 (Staphylococcus phage SAP090B, partial sequence) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

28. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NC_004617 (Staphylococcus prophage phi 13, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

29. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to KY653125 (Staphylococcus phage IME1346_01, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

30. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NC_021773 (Staphylococcus phage JS01, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

31. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to MH401414 (Staphylococcus aureus phage SA45ruMSSAST97, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

32. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to MH401415 (Staphylococcus aureus phage SA537ruMSSAST97, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

33. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to KX232515 (Staphylococcus phage 3 AJ-2017, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

34. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NC_009761 (Staphylococcus phage tp310-1, complete sequence) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

35. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

36. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to AB243556 (Staphylococcus phage phiPVL108 DNA, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

37. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NC_008689 (Staphylococcus phage phiPVL108, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

38. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to MH384260 (Staphylococcus phage SA780ruMSSAST101, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

39. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NC_048658 (Staphylococcus phage SA7, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

40. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NC_009763 (Staphylococcus phage tp310-3, complete sequence) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

41. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NC_002321 (Staphylococcus phage PVL proviral DNA, complete sequence) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

42. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to NC_002486 (Staphylococcus prophage phiPV83, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

43. spacer 4.16|1549080|23|NZ_AP014944|CRT matches to FJ713816 (Staphylococcus phage phiPVL-CN125, complete genome) position: , mismatch: 2, identity: 0.913

aatccatttcagcgcaataaaca	CRISPR spacer
aatccatttcagcacaatataca	Protospacer
*************.***** ***

44. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to KX827371 (Staphylococcus phage SpT99F3, complete genome) position: , mismatch: 2, identity: 0.926

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tctgagtccatttcagcgcaataaaca	Protospacer
**.**.*********************

45. spacer 1.25|67820|36|NZ_AP014944|PILER-CR matches to MK936475 (Staphylococcus phage SA03-CTH2, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataagaatattttagg	Protospacer
 ********.**************.***********

46. spacer 1.25|67820|36|NZ_AP014944|PILER-CR matches to MT926124 (Staphylococcus phage vB_SauP_EBHT, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataaaaatatttttgg	Protospacer
 ********.*********************** **

47. spacer 1.25|67820|36|NZ_AP014944|PILER-CR matches to MK922548 (Staphylococcus phage SA46-CTH4, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataagaatattttagg	Protospacer
 ********.**************.***********

48. spacer 1.25|67820|36|NZ_AP014944|PILER-CR matches to MK922547 (Staphylococcus phage SA30-CTH2, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataagaatattttagg	Protospacer
 ********.**************.***********

49. spacer 1.25|67820|36|NZ_AP014944|PILER-CR matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataaaaatatttttgg	Protospacer
 ********.*********************** **

50. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NC_003042 (Clostridium perfringens str. 13 plasmid pCP13, complete sequence) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
attttatcttcagcttttttatctt	Protospacer
 .******************.****

51. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NC_023917 (Clostridium perfringens plasmid pCP-OS1 DNA, complete sequence, strain: OS1) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
attttatcttcagcttttttatctt	Protospacer
 .******************.****

52. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NC_023918 (Clostridium perfringens plasmid pCP-TS1 DNA, complete sequence, strain: TS1) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
attttatcttcagcttttttatctt	Protospacer
 .******************.****

53. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NZ_MK275619 (Clostridium perfringens strain JXJA17 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
attttatcttcagcttttttatctt	Protospacer
 .******************.****

54. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NZ_CP014218 (Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
tctttatctttagcttttttatctt	Protospacer
.*********.*********.****

55. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to KM236237 (Citrobacter phage Miller, complete genome) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
gctttatgttcatcttttttgtctt	Protospacer
 ****** **** ************

56. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to KC801932 (Escherichia phage Lw1, complete genome) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
gctttatgttcatcttttttgtctt	Protospacer
 ****** **** ************

57. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to MK448931 (Streptococcus phage Javan414, complete genome) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
actttatcttctgcttttttggctt	Protospacer
 ********** ********* ***

58. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NC_031057 (Citrobacter phage vB_CfrM_CfP1, complete genome) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
gctttatgttcatcttttttgtctt	Protospacer
 ****** **** ************

59. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 3, identity: 0.88

cctttatcttcagcttttttgtctt	CRISPR spacer
tctttatctttagcttttttatctt	Protospacer
.*********.*********.****

60. spacer 4.2|1549139|30|NZ_AP014944|CRISPRCasFinder,CRT matches to MF417958 (Uncultured Caudovirales phage clone 7F_13, partial genome) position: , mismatch: 3, identity: 0.9

gattgatagtttgcgattcttgcagtcatt	CRISPR spacer
gattgatagtttgcgtttcttacagtcact	Protospacer
*************** *****.******.*

61. spacer 4.9|1549601|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MK075001 (Staphylococcus phage phiSP15-1, complete genome) position: , mismatch: 3, identity: 0.9

ccatgatgtctaaaaacaccgatttaccat	CRISPR spacer
tcatgatgtctaaaaatactgatttaccat	Protospacer
.***************.**.**********

62. spacer 4.9|1549601|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 3, identity: 0.9

ccatgatgtctaaaaacaccgatttaccat	CRISPR spacer
tcatgatgtctaaaaatactgatttaccat	Protospacer
.***************.**.**********

63. spacer 4.18|1549157|30|NZ_AP014944|PILER-CR matches to MF417958 (Uncultured Caudovirales phage clone 7F_13, partial genome) position: , mismatch: 3, identity: 0.9

gattgatagtttgcgattcttgcagtcatt	CRISPR spacer
gattgatagtttgcgtttcttacagtcact	Protospacer
*************** *****.******.*

64. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to CP015514 (Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
ttcttatctacagcttttttgtctt	Protospacer
...****** ***************

65. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NZ_CP018877 (Bacillus megaterium strain JX285 plasmid 4, complete sequence) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
attttattttcatcttttttgtctt	Protospacer
 .*****.**** ************

66. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NZ_CP045273 (Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
actttttcttcaacttttttgtcta	Protospacer
 **** ******.***********

67. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to MT366947 (Bacillus phage Hyb2phi3Ts-SPbeta, complete genome) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcagctttttgttgat	Protospacer
*******************  *  *

68. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to KY030782 (Bacillus phage phi3T, complete genome) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcagctttttgttgat	Protospacer
*******************  *  *

69. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NC_001884 (Bacillus phage SPBc2, complete genome) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcagctttttgttgat	Protospacer
*******************  *  *

70. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to AF020713 (Bacteriophage SPBc2 complete genome) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcagctttttgttgat	Protospacer
*******************  *  *

71. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to MT366946 (Bacillus phage Hyb1phi3Ts-SPbeta, complete genome) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcagctttttgttgat	Protospacer
*******************  *  *

72. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to MT366948 (Bacillus phage Hyb3phi3Ts-SPbeta, complete genome) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcagctttttgttgat	Protospacer
*******************  *  *

73. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to CP052843 (Bacillus phage Hybphi3Ts, partial sequence) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcagctttttgttgat	Protospacer
*******************  *  *

74. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to MT366945 (Bacillus phage phi3Ts, complete genome) position: , mismatch: 4, identity: 0.84

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcagctttttgttgat	Protospacer
*******************  *  *

75. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to KX232515 (Staphylococcus phage 3 AJ-2017, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

76. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to AF424783 (Staphylococcus aureus phage phi 13, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

77. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to AB044554 (Staphylococcus prophage phiPV83 proviral DNA, complete sequence) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

78. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to GQ915271 (Staphylococcus phage SAP090B, partial sequence) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

79. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to NC_004617 (Staphylococcus prophage phi 13, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

80. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to KY389064 (Staphylococcus phage phi879, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tcattatccatttcagcacaataaaca	Protospacer
**   ************.*********

81. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to KY653125 (Staphylococcus phage IME1346_01, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

82. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to NC_021773 (Staphylococcus phage JS01, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

83. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to MH401414 (Staphylococcus aureus phage SA45ruMSSAST97, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

84. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to MH401415 (Staphylococcus aureus phage SA537ruMSSAST97, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

85. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to NC_009761 (Staphylococcus phage tp310-1, complete sequence) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

86. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

87. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to KY389063 (Staphylococcus phage phi575, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tcattatccatttcagcacaataaaca	Protospacer
**   ************.*********

88. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to AB243556 (Staphylococcus phage phiPVL108 DNA, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

89. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to NC_008689 (Staphylococcus phage phiPVL108, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

90. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to MH384260 (Staphylococcus phage SA780ruMSSAST101, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

91. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to NC_048658 (Staphylococcus phage SA7, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

92. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to NC_009763 (Staphylococcus phage tp310-3, complete sequence) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

93. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to NC_002321 (Staphylococcus phage PVL proviral DNA, complete sequence) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

94. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to NC_002486 (Staphylococcus prophage phiPV83, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

95. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to FJ713816 (Staphylococcus phage phiPVL-CN125, complete genome) position: , mismatch: 4, identity: 0.852

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tgtgaatccatttcagcacaatataca	Protospacer
* .**************.***** ***

96. spacer 3.1|200168|25|NZ_AP014944|CRISPRCasFinder matches to NC_014533 (Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence) position: , mismatch: 5, identity: 0.8

cctttatcttcagcttttttgtctt	CRISPR spacer
cctttatcttcatcttttttgatac	Protospacer
************ ******** . .

97. spacer 4.1|1549074|29|NZ_AP014944|CRISPRCasFinder matches to KY389064 (Staphylococcus phage phi879, complete genome) position: , mismatch: 5, identity: 0.828

cttccgaatccatttcagcgcaataaaca	CRISPR spacer
cgtcattatccatttcagcacaataaaca	Protospacer
* **   ************.*********

98. spacer 4.1|1549074|29|NZ_AP014944|CRISPRCasFinder matches to KY389063 (Staphylococcus phage phi575, complete genome) position: , mismatch: 5, identity: 0.828

cttccgaatccatttcagcgcaataaaca	CRISPR spacer
cgtcattatccatttcagcacaataaaca	Protospacer
* **   ************.*********

99. spacer 4.2|1549139|30|NZ_AP014944|CRISPRCasFinder,CRT matches to NC_013378 (Staphylococcus epidermidis plasmid SAP105B, complete sequence) position: , mismatch: 5, identity: 0.833

gattgatagtttgcgattcttgcagtcatt-	CRISPR spacer
gattgatattttgcgattctt-cagtaaaag	Protospacer
******** ************ **** *

100. spacer 4.18|1549157|30|NZ_AP014944|PILER-CR matches to NC_013378 (Staphylococcus epidermidis plasmid SAP105B, complete sequence) position: , mismatch: 5, identity: 0.833

gattgatagtttgcgattcttgcagtcatt-	CRISPR spacer
gattgatattttgcgattctt-cagtaaaag	Protospacer
******** ************ **** *

101. spacer 1.16|67961|35|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP043848 (Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.829

ggtaatagttgctcaataggtaataaaacgtcggt	CRISPR spacer
gggaatagttgctcgataggtaataaaacgtttac	Protospacer
** ***********.****************. ..

102. spacer 2.2|76863|41|NZ_AP014944|CRISPRCasFinder matches to MF417907 (Uncultured Caudovirales phage clone 7F_7, partial genome) position: , mismatch: 6, identity: 0.854

aactgatatactcctttaccatgtattaattctggaccact	CRISPR spacer
tattcatatactcccttgccatgtattaattctggaccacg	Protospacer
 *.* *********.**.**********************

103. spacer 2.2|76863|41|NZ_AP014944|CRISPRCasFinder matches to KY653129 (Staphylococcus phage IME1365_01, complete genome) position: , mismatch: 6, identity: 0.854

aactgatatactcctttaccatgtattaattctggaccact	CRISPR spacer
tattcataaactcctttgccatgtattaattctggaccacg	Protospacer
 *.* *** ********.**********************

104. spacer 4.12|1549798|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX858825 (Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence) position: , mismatch: 6, identity: 0.8

gtaaataattccgtttggactcgttacgtt	CRISPR spacer
gtgtatcattccgtttggactggttactct	Protospacer
**. ** ************** ***** .*

105. spacer 4.17|1549091|27|NZ_AP014944|PILER-CR matches to KY653118 (Morganella phage IME1369_01, complete genome) position: , mismatch: 6, identity: 0.778

tccgaatccatttcagcgcaataaaca	CRISPR spacer
tccgaaaccatttcatcgcaatacctg	Protospacer
****** ******** *******  ..

106. spacer 2.5|76862|42|NZ_AP014944|CRT matches to KY653129 (Staphylococcus phage IME1365_01, complete genome) position: , mismatch: 7, identity: 0.833

gaactgatatactcctttaccatgtattaattctggaccact	CRISPR spacer
atattcataaactcctttgccatgtattaattctggaccacg	Protospacer
. *.* *** ********.**********************

107. spacer 2.5|76862|42|NZ_AP014944|CRT matches to MF417907 (Uncultured Caudovirales phage clone 7F_7, partial genome) position: , mismatch: 7, identity: 0.833

gaactgatatactcctttaccatgtattaattctggaccact	CRISPR spacer
atattcatatactcccttgccatgtattaattctggaccacg	Protospacer
. *.* *********.**.**********************

108. spacer 4.1|1549074|29|NZ_AP014944|CRISPRCasFinder matches to KY653118 (Morganella phage IME1369_01, complete genome) position: , mismatch: 7, identity: 0.759

cttccgaatccatttcagcgcaataaaca	CRISPR spacer
catccgaaaccatttcatcgcaatacctg	Protospacer
* ****** ******** *******  ..

109. spacer 4.10|1549667|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

acgttagatttgcaggtgttaagcacggct	CRISPR spacer
cggattgatttgcaggtgataagcacagcc	Protospacer
  * * ************ *******.**.

110. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MT758689 (Lactobacillus phage Lbab1, complete genome) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
atgttttttcatcaaagttaccatatactt	Protospacer
************.****.*****   *.*.

111. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NC_012530 (Lactobacillus phage Lb338-1, complete genome) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
atgttttttcatcaaagttaccatatactt	Protospacer
************.****.*****   *.*.

112. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022441 (Klebsiella sp. LY plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
ctcaatcttcattaaagcaaccattaattc	Protospacer
 *   *.*********** **** ******

113. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to KU318421 (Klebsiella pneumoniae strain KP04 plasmid pKP04VIM, complete sequence) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
ctcaatcttcattaaagcaaccattaattc	Protospacer
 *   *.*********** **** ******

114. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NC_023911 (Raoultella planticola strain KpNDM1 plasmid pKpNDM1, complete sequence) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
ctcaatcttcattaaagcaaccattaattc	Protospacer
 *   *.*********** **** ******

115. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025964 (Klebsiella pneumoniae strain WCHKP34 plasmid pIMP4_LL34, complete sequence) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
ctcaatcttcattaaagcaaccattaattc	Protospacer
 *   *.*********** **** ******

116. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026019 (Klebsiella pneumoniae strain 13190 plasmid p13190-1, complete sequence) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
ctcaatcttcattaaagcaaccattaattc	Protospacer
 *   *.*********** **** ******

117. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MF344566 (Klebsiella pneumoniae strain A324 plasmid pA324-IMP, complete sequence) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
ctcaatcttcattaaagcaaccattaattc	Protospacer
 *   *.*********** **** ******

118. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MF344563 (Klebsiella pneumoniae strain 13190 plasmid p13190-VIM, complete sequence) position: , mismatch: 7, identity: 0.767

atgttttttcattaaagctaccagtaattc	CRISPR spacer
ctcaatcttcattaaagcaaccattaattc	Protospacer
 *   *.*********** **** ******

119. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to MN694790 (Marine virus AFVG_250M551, complete genome) position: , mismatch: 8, identity: 0.765

aattttctaattctataagttcattaattccgat	CRISPR spacer
aattttctatttctataatttcattacactctag	Protospacer
********* ******** *******  ..* *

120. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_LR214999 (Mycoplasma conjunctivae strain NCTC10147 plasmid 3) position: , mismatch: 8, identity: 0.765

aattttctaattctataagttcattaattccgat	CRISPR spacer
gtttagctaattctataagttcattgtttctggt	Protospacer
. **  *******************. ***.*.*

121. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to LR214965 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11) position: , mismatch: 8, identity: 0.765

aattttctaattctataagttcattaattccgat	CRISPR spacer
gtttagctaattctataagttcattgtttctggt	Protospacer
. **  *******************. ***.*.*

122. spacer 4.4|1549271|30|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 8, identity: 0.733

tcgtcatcaatccatcgccatatgcttctt	CRISPR spacer
gacacatcaatccattgccgtatgcttggt	Protospacer
    ***********.***.*******  *

123. spacer 4.15|1549996|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP036543 (Bacteroides fragilis strain DCMOUH0018B plasmid pBFO18_1, complete sequence) position: , mismatch: 8, identity: 0.733

aattcgcctttatattcaggtttctttttt	CRISPR spacer
acccttgcttcatattcaggtttctttatt	Protospacer
* ...  ***.**************** **

124. spacer 4.15|1549996|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032274 (Acinetobacter sp. WCHAc010034 plasmid p6_010034, complete sequence) position: , mismatch: 8, identity: 0.733

aattcgcctttatattcaggtttctttttt	CRISPR spacer
actatttttttatattcaggtttttttttc	Protospacer
* * . ..***************.*****.

125. spacer 4.15|1549996|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MT411892 (Staphylococcus phage Metroid, complete genome) position: , mismatch: 8, identity: 0.733

aattcgcctttatattcaggtttctttttt	CRISPR spacer
aaatcgactttatattcaggttttaaatca	Protospacer
** *** ****************.   *.

126. spacer 4.15|1549996|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to AP018375 (Staphylococcus phage phiSA039 DNA, complete genome) position: , mismatch: 8, identity: 0.733

aattcgcctttatattcaggtttctttttt	CRISPR spacer
aaatcgactttatattcaggttttaaatca	Protospacer
** *** ****************.   *.

127. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 9, identity: 0.735

aattttctaattctataagttcattaattccgat	CRISPR spacer
ctttgactaattctacaagttcatttattctatt	Protospacer
  **  *********.********* ****.. *

128. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MT150133 (Enterobacteria phage vB_EcoM_IME540, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

129. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NC_028925 (Enterobacteria phage vB_EcoM_VR25, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

130. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MK234886 (Escherichia phage AnYang, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

131. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MT446420 (UNVERIFIED: Escherichia virus TH54, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

132. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to KU878969 (Escherichia phage MX01, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

133. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to KY979109 (Salmonella phage SHP1, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

134. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to NC_019500 (Enterobacteria phage Bp7, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

135. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MK295203 (Escherichia phage vB_EcoM_005, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

136. spacer 4.14|1549930|30|NZ_AP014944|CRISPRCasFinder,CRT,PILER-CR matches to MH051913 (Enterobacteria phage vB_EcoM_IME281, complete genome) position: , mismatch: 9, identity: 0.7

atgttttttcattaaagctaccagtaattc	CRISPR spacer
gcaggttttcaataaagctacgagtaatag	Protospacer
...  ****** ********* ******

137. spacer 4.2|1549139|30|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP017759 (Cupriavidus necator strain NH9 plasmid pENH92, complete sequence) position: , mismatch: 10, identity: 0.667

gattgatagtttgcgattcttgcagtcatt	CRISPR spacer
ctacgatactttgcgattcttgcagaggag	Protospacer
   .**** ****************  .

138. spacer 4.18|1549157|30|NZ_AP014944|PILER-CR matches to NZ_CP017759 (Cupriavidus necator strain NH9 plasmid pENH92, complete sequence) position: , mismatch: 10, identity: 0.667

gattgatagtttgcgattcttgcagtcatt	CRISPR spacer
ctacgatactttgcgattcttgcagaggag	Protospacer
   .**** ****************  .

139. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP028886 (Borrelia turcica IST7 plasmid lp32-A, complete sequence) position: , mismatch: 11, identity: 0.676

aattttctaattctataagttcattaattccgat	CRISPR spacer
tcttttctaattctttaagtttattattcttttc	Protospacer
  ************ ******.**** *...  .

140. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

aattttctaattctataagttcattaattccgat	CRISPR spacer
tgagacggaatactataagttcattaactccgga	Protospacer
 .   .  *** ***************.****.

141. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

aattttctaattctataagttcattaattccgat	CRISPR spacer
tgagacggaatactataagttcattaactccgga	Protospacer
 .   .  *** ***************.****.

142. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

aattttctaattctataagttcattaattccgat	CRISPR spacer
tgagacggaatactataagttcattaactccgga	Protospacer
 .   .  *** ***************.****.

143. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

aattttctaattctataagttcattaattccgat	CRISPR spacer
tgagacggaatactataagttcattaactccgga	Protospacer
 .   .  *** ***************.****.

144. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

aattttctaattctataagttcattaattccgat	CRISPR spacer
tgagacggaatactataagttcattaactccgga	Protospacer
 .   .  *** ***************.****.

145. spacer 1.5|67173|34|NZ_AP014944|CRISPRCasFinder,CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

aattttctaattctataagttcattaattccgat	CRISPR spacer
tgagacggaatactataagttcattaactccgga	Protospacer
 .   .  *** ***************.****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

164347 : 230001

Tupanvirus(33.33%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060829194.1\|164347_165526_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_060829195.1\|165735_166221_+	peptide-methionine (S)-S-oxide reductase	NA	NA	NA	NA
WP_060829196.1\|166294_166897_-	response regulator transcription factor	NA	NA	NA	NA
WP_060829197.1\|166893_167994_-	sensor histidine kinase	NA	NA	NA	NA
WP_060830485.1\|167990_168725_-	ABC transporter permease	NA	NA	NA	NA
WP_060829198.1\|168724_169591_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.5e-18	26.2
WP_060829199.1\|169960_173098_+	ATP-binding protein	NA	NA	NA	NA
WP_060829200.1\|173234_174086_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_060829201.1\|174190_176149_-	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_060829202.1\|176164_177055_-	N-acetylmuramic acid 6-phosphate etherase	NA	NA	NA	NA
WP_060829203.1\|177056_178121_-	DUF871 domain-containing protein	NA	NA	NA	NA
WP_060829204.1\|178525_182227_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.5e-80	28.3
WP_171839456.1\|182231_185675_+	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	7.2e-56	27.5
WP_060829206.1\|185685_186309_+	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_060829207.1\|186503_186905_+	hypothetical protein	NA	NA	NA	NA
WP_060829208.1\|187053_187881_+	autolysin	NA	NA	NA	NA
WP_060829209.1\|188085_188274_+	hypothetical protein	NA	NA	NA	NA
WP_060829211.1\|188862_191658_+	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_060829212.1\|191740_192322_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_060829213.1\|192323_193880_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.5e-210	74.2
WP_060829214.1\|193872_195105_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.2e-42	35.3
WP_060829215.1\|195247_195826_-	DUF2812 domain-containing protein	NA	NA	NA	NA
WP_060829216.1\|195812_196139_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_060829217.1\|196515_196842_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_103356157.1\|197678_198158_-	YagU family protein	NA	NA	NA	NA
WP_060829219.1\|198503_199514_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_060829220.1\|199695_201363_-	staphylococcal protein A	NA	NA	NA	NA
WP_060829221.1\|202144_202858_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_060829222.1\|202876_203818_-	carbamate kinase	NA	NA	NA	NA
WP_060829223.1\|203834_205265_-	arginine-ornithine antiporter	NA	NA	NA	NA
WP_060829224.1\|205384_206392_-	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_060829225.1\|206427_207663_-	arginine deiminase	NA	NA	NA	NA
WP_060829226.1\|208088_208568_+	ArgR family transcriptional regulator	NA	NA	NA	NA
WP_060829227.1\|208665_209259_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_060829228.1\|209453_211229_+	oleate hydratase	NA	NA	NA	NA
WP_060829229.1\|211488_212076_+	DsbA family protein	NA	NA	NA	NA
WP_060829230.1\|212501_213269_+\|protease	serine protease	NA	NA	NA	NA
WP_060829231.1\|213531_214299_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_060829232.1\|214800_215967_-	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_103356450.1\|215977_216511_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_060829233.1\|216803_217142_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_060830487.1\|217205_218006_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_060829234.1\|218573_219545_+	chitosanase	A0A223LI87	Streptomyces_phage	2.9e-18	36.9
WP_060829235.1\|219569_220832_+	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_060829236.1\|220944_221679_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_060829237.1\|222230_223601_+	MFS transporter	NA	NA	NA	NA
WP_050329883.1\|223631_224294_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_060829238.1\|224333_225512_+	phosphopentomutase	NA	NA	NA	NA
WP_060829239.1\|225676_226588_+	hypothetical protein	NA	NA	NA	NA
WP_060829240.1\|227045_227774_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_060829241.1\|227820_228528_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_060829242.1\|228681_230001_-\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

915133 : 944733

uncultured_Caudovirales_phage(31.25%)

head,transposase,protease,tRNA,integrase,capsid,portal

attL 934924:934941|attR 948321:948338

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050330452.1\|915133_915580_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_060829618.1\|915572_916229_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_060830504.1\|916252_916678_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_060829619.1\|916670_917699_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.0e-61	40.3
WP_060829620.1\|918147_920091_-	ABC-F type ribosomal protection protein	A0A2K9L3Z8	Tupanvirus	1.6e-52	29.7
WP_060829621.1\|920243_920882_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_050345383.1\|921174_922257_+	YeeE/YedE family protein	NA	NA	NA	NA
WP_050330465.1\|922281_922506_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_060829622.1\|922903_924391_+	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	1.5e-10	24.0
WP_060829242.1\|924459_925779_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_050330468.1\|925965_926682_-	response regulator transcription factor	A0A2H4J4Z6	uncultured_Caudovirales_phage	6.1e-26	32.2
WP_060829623.1\|926696_927989_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_060829624.1\|928015_928150_-	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_060829625.1\|928152_928719_-	accessory gene regulator AgrB	NA	NA	NA	NA
WP_103356492.1\|929125_929203_+	delta-lysin family phenol-soluble modulin	NA	NA	NA	NA
WP_060829626.1\|929444_930248_-	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_060829627.1\|930413_931922_+	hypothetical protein	NA	NA	NA	NA
WP_060829628.1\|932034_932787_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_016425569.1\|932991_933276_+	co-chaperone GroES	A0A221S4A8	uncultured_virus	2.1e-14	39.1
WP_050330477.1\|933321_934941_+	chaperonin GroEL	A0A240F779	uncultured_virus	4.4e-157	54.0
934924:934941	attL	NA	NA	NA	NA
WP_060829629.1\|935056_936229_-\|integrase	site-specific integrase	A0A2H4JBC4	uncultured_Caudovirales_phage	6.6e-195	87.5
WP_060829630.1\|936237_936825_-	helix-turn-helix transcriptional regulator	A0A1W6JPB6	Staphylococcus_phage	5.4e-20	34.9
WP_060829631.1\|936921_937158_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_060829632.1\|937144_937450_+	helix-turn-helix domain-containing protein	A0A2H4JHK0	uncultured_Caudovirales_phage	3.9e-38	81.2
WP_060829633.1\|937446_937650_+	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	4.0e-23	73.1
WP_060829634.1\|937652_937859_+	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	1.3e-16	62.1
WP_060829635.1\|937860_938133_+	hypothetical protein	NA	NA	NA	NA
WP_060829636.1\|938132_938435_+	DUF1474 family protein	A0A2H4JB50	uncultured_Caudovirales_phage	2.2e-30	66.7
WP_060829637.1\|938532_940902_+	DNA primase	A0A2H4JCU9	uncultured_Caudovirales_phage	2.0e-145	42.2
WP_060829638.1\|941287_941632_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	4.5e-43	69.6
WP_082704434.1\|941815_942949_+\|portal	phage portal protein	A0A1L2BY94	Clostridium_phage	3.1e-56	34.9
WP_060829640.1\|942935_943502_+\|head,protease	HK97 family phage prohead protease	A0A1B1PA08	Enterococcus_phage	1.0e-20	34.9
WP_060829641.1\|943503_944733_+\|capsid	phage major capsid protein	NA	NA	NA	NA
948321:948338	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1099938 : 1123526

Staphylococcus_phage(90.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060829727.1\|1099938_1100256_-	DUF4870 domain-containing protein	A0A2H4J741	uncultured_Caudovirales_phage	5.6e-16	48.0
WP_060829728.1\|1100549_1101944_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.8e-130	52.5
WP_060829729.1\|1101940_1102930_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.3e-79	45.7
WP_050330616.1\|1102905_1103157_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	3.5e-29	69.9
WP_050330617.1\|1103214_1103685_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	8.9e-34	47.8
WP_050330618.1\|1103665_1104436_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.8e-84	62.7
WP_060829730.1\|1104566_1106150_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	2.4e-240	75.6
WP_050330620.1\|1106697_1107897_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	3.1e-179	80.8
WP_050332160.1\|1107986_1108898_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	2.1e-87	67.9
WP_060829731.1\|1109487_1110324_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.2e-111	68.2
WP_060829732.1\|1110463_1110820_-	CrcB family protein	NA	NA	NA	NA
WP_060829733.1\|1110816_1111182_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	1.3e-32	59.3
WP_060829734.1\|1111218_1111521_-	hypothetical protein	NA	NA	NA	NA
WP_050330625.1\|1111676_1112387_+	transaldolase	M1PR54	Cyanophage	5.0e-20	37.0
WP_060829735.1\|1112633_1113083_+	hypothetical protein	NA	NA	NA	NA
WP_060829736.1\|1113085_1113514_-	hypothetical protein	NA	NA	NA	NA
WP_082704409.1\|1113516_1114005_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	3.1e-21	43.8
WP_016425399.1\|1114209_1114431_+	hypothetical protein	NA	NA	NA	NA
WP_060829737.1\|1114587_1115451_+	N-acetylglucosaminidase	A0A1W6JQU5	Staphylococcus_phage	7.9e-36	43.9
WP_103356715.1\|1115772_1116660_-	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_060829739.1\|1116885_1118445_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	3.4e-13	60.3
WP_060829740.1\|1118984_1120031_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.5e-113	57.8
WP_050330632.1\|1120035_1120665_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.8e-61	57.1
WP_050330633.1\|1120679_1121861_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.7e-150	65.4
WP_050345483.1\|1121879_1122338_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.2e-51	66.7
WP_050345484.1\|1122542_1123526_-	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	1.5e-120	66.9

DBSCAN-SWA_4

1126736 : 1135476

Staphylococcus_phage(85.71%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060829742.1\|1126736_1127219_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	9.8e-20	35.4
WP_060829743.1\|1127628_1128039_+	transcriptional regulator	NA	NA	NA	NA
WP_060829744.1\|1128089_1128650_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	2.7e-61	61.1
WP_050345488.1\|1128646_1129600_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	6.4e-63	78.5
WP_060829745.1\|1129744_1130926_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	4.8e-153	68.7
WP_060829746.1\|1131301_1133713_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	80.5
WP_060829747.1\|1133731_1134043_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.1e-32	64.1
WP_060829748.1\|1134219_1135476_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	2.0e-32	69.5

DBSCAN-SWA_5

1249827 : 1261161

uncultured_Mediterranean_phage(57.14%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016425273.1\|1249827_1250826_+	Holliday junction branch migration DNA helicase RuvB	E3T4M7	Cafeteria_roenbergensis_virus	2.6e-06	27.1
WP_050345539.1\|1250843_1251869_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_060829804.1\|1251886_1253026_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.0e-87	45.5
WP_060829805.1\|1253042_1253306_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	3.0e-07	45.7
WP_060829806.1\|1253444_1255724_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	6.1e-27	31.6
WP_060830513.1\|1255832_1258115_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.4e-69	29.0
WP_050330737.1\|1258128_1258647_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.2e-26	48.0
WP_050330738.1\|1258971_1261161_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	7.7e-11	36.5

DBSCAN-SWA_6

1394550 : 1403546

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060829882.1\|1394550_1395279_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.8e-10	30.6
WP_060829883.1\|1395268_1395811_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.3e-09	32.7
WP_050330852.1\|1395810_1396554_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_050331964.1\|1396848_1397574_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.6e-45	40.9
WP_060829884.1\|1397557_1399300_+	HAMP domain-containing protein	Q8QKV4	Ectocarpus_siliculosus_virus	4.4e-09	25.0
WP_050345599.1\|1400011_1400557_+	ECF transporter S component	NA	NA	NA	NA
WP_014613875.1\|1400879_1401128_-	ferredoxin	A0A127AYY7	Bacillus_phage	2.3e-17	53.3
WP_060829885.1\|1401232_1402177_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_060829886.1\|1402169_1403546_+	ATP-dependent DNA helicase RecQ	A0A0G2Y8K9	Acanthamoeba_polyphaga_mimivirus	1.9e-55	34.0

DBSCAN-SWA_7

1822213 : 1830633

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060830108.1\|1822213_1822780_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.8e-25	36.9
WP_050345828.1\|1822776_1823811_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	7.7e-62	41.5
WP_060830109.1\|1823814_1825236_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.2e-50	33.5
WP_060830110.1\|1825214_1827404_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.5e-136	39.2
WP_050331381.1\|1827396_1828068_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_016424734.1\|1828069_1828330_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_060830111.1\|1828332_1829034_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	2.8e-47	42.1
WP_060830112.1\|1829030_1830164_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_050331384.1\|1830150_1830633_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.0e-21	44.7

DBSCAN-SWA_8

2001632 : 2045943

Staphylococcus_phage(88.89%)

head,plate,protease,terminase,holin,integrase,capsid,tail,portal

attL 2039688:2039703|attR 2048016:2048031

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_060830199.1\|2001632_2002319_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_060830525.1\|2002639_2003038_-	hypothetical protein	NA	NA	NA	NA
WP_060830200.1\|2003780_2004536_-	CHAP domain-containing protein	A0A1J0MF88	Staphylococcus_phage	2.4e-145	96.0
WP_060830201.1\|2004548_2004803_-\|holin	phage holin	A0A1J0MFP5	Staphylococcus_phage	1.4e-38	96.4
WP_060830202.1\|2004820_2006710_-	glucosaminidase domain-containing protein	A0A1J0MFI1	Staphylococcus_phage	0.0e+00	98.9
WP_015728845.1\|2006832_2007207_-	hypothetical protein	A0A1J0MFD0	Staphylococcus_phage	1.1e-53	100.0
WP_060830203.1\|2007239_2008511_-\|plate	BppU family phage baseplate upper protein	A0A1J0MFQ3	Staphylococcus_phage	2.9e-236	97.9
WP_060830204.1\|2008527_2009571_-	SGNH/GDSL hydrolase family protein	A0A1J0MFI8	Staphylococcus_phage	1.1e-188	98.6
WP_060830205.1\|2009582_2010275_-	hypothetical protein	A0A1J0MFH9	Staphylococcus_phage	2.3e-102	99.6
WP_060830206.1\|2010278_2011676_-	hypothetical protein	A0A1J0MF94	Staphylococcus_phage	1.3e-237	92.3
WP_060830207.1\|2011688_2012621_-\|tail	phage tail family protein	A0A1J0MF79	Staphylococcus_phage	9.0e-179	99.7
WP_060830208.1\|2012633_2015753_-\|tail	phage tail protein	A0A223LI73	Staphylococcus_phage	1.5e-246	98.3
WP_015728838.1\|2015769_2016120_-	hypothetical protein	A0A1J0MFN5	Staphylococcus_phage	3.0e-58	100.0
WP_060830209.1\|2016149_2016530_-\|tail	tail assembly chaperone	A0A1J0MFC0	Staphylococcus_phage	1.1e-63	100.0
WP_015728836.1\|2016589_2017243_-\|tail	phage major tail protein, TP901-1 family	A0A1J0MG89	Staphylococcus_phage	1.1e-69	100.0
WP_060830210.1\|2017260_2017656_-	hypothetical protein	Q4ZE28	Staphylococcus_virus	1.3e-54	81.7
WP_060830211.1\|2017665_2018016_-	HK97 gp10 family phage protein	A0A1J0MFN9	Staphylococcus_phage	1.3e-50	83.6
WP_060830212.1\|2018005_2018320_-	hypothetical protein	A0A1J0MF86	Staphylococcus_phage	1.7e-49	100.0
WP_060830213.1\|2018316_2018649_-\|head,tail	phage head-tail connector protein	A0A1J0MFR4	Staphylococcus_phage	4.2e-54	99.1
WP_060830214.1\|2018660_2019110_-	Ig domain-containing protein	A0A1J0MFM7	Staphylococcus_phage	1.9e-73	100.0
WP_060830215.1\|2019199_2020111_-	hypothetical protein	A0A1J0MFM8	Staphylococcus_phage	1.1e-165	99.7
WP_060830216.1\|2020128_2020737_-	DUF4355 domain-containing protein	A0A1J0MFB3	Staphylococcus_phage	1.5e-49	99.0
WP_014613564.1\|2020888_2021083_-	hypothetical protein	A0A1J0MG79	Staphylococcus_phage	6.3e-18	67.2
WP_060830526.1\|2021079_2022432_-\|capsid	minor capsid protein	A0A1J0MF61	Staphylococcus_phage	3.1e-236	93.3
WP_060830217.1\|2022424_2023870_-\|portal	phage portal protein	A0A1J0MFG2	Staphylococcus_phage	6.3e-272	99.2
WP_110165026.1\|2023881_2025159_-\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	1.3e-196	75.7
WP_060830219.1\|2025151_2025493_-	helix-turn-helix domain-containing protein	A0A2H4IYT3	uncultured_Caudovirales_phage	4.9e-34	67.3
WP_060830220.1\|2025522_2026077_-	GIY-YIG nuclease family protein	A1BU52	Staphylococcus_virus	7.1e-14	47.7
WP_037543601.1\|2026364_2026790_-	sigma-70 family RNA polymerase sigma factor	A0A1J0MFD1	Staphylococcus_phage	7.5e-72	100.0
WP_154800885.1\|2026790_2026934_-	hypothetical protein	A0A1J0MFM4	Staphylococcus_phage	7.4e-16	100.0
WP_060830221.1\|2026933_2027101_-	transcriptional regulator	A0A1J0MFF2	Staphylococcus_phage	3.1e-21	98.2
WP_037542749.1\|2027116_2027305_-	DUF1381 domain-containing protein	A0A223LFC9	Staphylococcus_phage	3.6e-26	100.0
WP_020219701.1\|2027341_2027878_-	dUTP diphosphatase	A0A1P8L6E0	Staphylococcus_phage	3.1e-75	76.4
WP_060830222.1\|2027870_2028182_-	hypothetical protein	NA	NA	NA	NA
WP_168250661.1\|2028198_2028360_-	hypothetical protein	A0A223LGT8	Staphylococcus_phage	5.0e-21	90.6
WP_015728818.1\|2028360_2028618_-	hypothetical protein	A0A1J0MFL3	Staphylococcus_phage	3.6e-37	92.9
WP_060830223.1\|2028617_2029016_-	hypothetical protein	A0A1J0MFF1	Staphylococcus_phage	3.4e-42	67.4
WP_082704421.1\|2029161_2029389_-	hypothetical protein	A0A1J0MFY5	Staphylococcus_phage	4.8e-25	86.8
WP_060830225.1\|2029369_2030047_-	N-6 DNA methylase	B7T0H3	Staphylococcus_virus	2.0e-87	70.1
WP_060830226.1\|2030043_2030529_-	DUF3310 domain-containing protein	A0A223LGV5	Staphylococcus_phage	2.4e-66	75.2
WP_168295458.1\|2030766_2030928_-	hypothetical protein	NA	NA	NA	NA
WP_037543623.1\|2030924_2031233_-	hypothetical protein	A0A223LH51	Staphylococcus_phage	4.8e-52	100.0
WP_060830228.1\|2031243_2031462_-	hypothetical protein	A0A1J0MFE4	Staphylococcus_phage	1.0e-32	98.6
WP_060830527.1\|2031454_2031829_-	RusA family crossover junction endodeoxyribonuclease	A0A1J0MFP7	Staphylococcus_phage	4.6e-65	97.6
WP_060830229.1\|2031886_2032066_-	hypothetical protein	A0A1J0MFQ5	Staphylococcus_phage	8.3e-25	94.9
WP_060830230.1\|2032059_2032833_-	ATP-binding protein	A0A1J0MFK2	Staphylococcus_phage	8.1e-141	98.4
WP_060830231.1\|2032842_2033580_-	conserved phage C-terminal domain-containing protein	Q6R839	Staphylococcus_virus	1.9e-83	72.1
WP_060830232.1\|2033654_2033933_+	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	1.6e-43	87.0
WP_168295453.1\|2033929_2034079_-	hypothetical protein	A7TWN0	Staphylococcus_phage	1.3e-07	64.6
WP_060830233.1\|2034071_2034746_-	hypothetical protein	A0A1J0MFS2	Staphylococcus_phage	1.2e-116	89.7
WP_015728805.1\|2034929_2035367_-	single-stranded DNA-binding protein	A0A1J0MFL8	Staphylococcus_phage	2.4e-73	98.6
WP_060830235.1\|2035366_2036035_-	ERF family protein	A0A1J0MFT8	Staphylococcus_phage	1.5e-119	99.5
WP_060830236.1\|2036035_2036521_-	siphovirus Gp157 family protein	A0A223LGF3	Staphylococcus_phage	5.0e-80	98.1
WP_060830237.1\|2036504_2036729_-	hypothetical protein	A0A223LFR3	Staphylococcus_phage	3.4e-31	98.6
WP_060830238.1\|2036740_2037001_-	DUF1108 family protein	A0A1J0MFJ8	Staphylococcus_phage	2.3e-39	95.3
WP_015728800.1\|2037246_2037471_-	hypothetical protein	A0A1J0MG48	Staphylococcus_phage	6.1e-33	100.0
WP_060830239.1\|2037467_2038211_-	ORF6C domain-containing protein	A0A223LFP5	Staphylococcus_phage	3.4e-136	99.6
WP_060830240.1\|2038288_2038516_+	hypothetical protein	A0A223LIF2	Staphylococcus_phage	1.9e-34	100.0
WP_015728797.1\|2038512_2038680_-	hypothetical protein	A0A1J0MFJ7	Staphylococcus_phage	1.5e-23	100.0
WP_015728794.1\|2038788_2039058_-	helix-turn-helix transcriptional regulator	H9A0Y0	Staphylococcus_phage	1.5e-38	93.3
WP_060830241.1\|2039191_2039896_+	helix-turn-helix transcriptional regulator	A0A1J0MFC5	Staphylococcus_phage	4.1e-91	73.1
2039688:2039703	attL	NA	NA	NA	NA
WP_060830528.1\|2040191_2040455_+	hypothetical protein	A0A1W6JQ94	Staphylococcus_phage	8.0e-24	65.5
WP_037543680.1\|2040502_2040940_+	DUF4231 domain-containing protein	A0A1J0MFR0	Staphylococcus_phage	4.3e-75	100.0
WP_037543682.1\|2040933_2041341_+	TIR domain-containing protein	A0A1J0MFJ5	Staphylococcus_phage	3.4e-74	100.0
WP_037543684.1\|2041337_2041535_-	hypothetical protein	A0A1J0MFE5	Staphylococcus_phage	4.3e-30	100.0
WP_060830242.1\|2041650_2042700_+\|integrase	site-specific integrase	A0A1J0MF14	Staphylococcus_phage	2.2e-202	100.0
WP_016424582.1\|2042767_2044165_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_050331554.1\|2044262_2044712_-	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_060830243.1\|2044701_2045943_-	cysteine desulfurase	Q2XUY6	environmental_halophage	2.0e-117	48.0
2048016:2048031	attR	NA	NA	NA	NA

DBSCAN-SWA_9

2121381 : 2131003

uncultured_Caudovirales_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050331610.1\|2121381_2123487_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	87.0
WP_050345966.1\|2123449_2123848_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	3.6e-44	64.4
WP_060830276.1\|2124471_2125359_+	DMT family transporter	NA	NA	NA	NA
WP_050331613.1\|2125375_2125876_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	4.1e-53	71.7
WP_060830277.1\|2126194_2127700_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.6e-68	34.4
WP_050331615.1\|2128381_2129884_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	5.3e-64	33.8
WP_060830278.1\|2130073_2131003_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	7.7e-13	25.5

Anti-CRISPR protein detection

Acr_ID: NZ_AP014944.1|WP_060830525.1|2002639_2003038_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_AP014944.1|WP_060830525.1|2002639_2003038_-|hypothetical-protein

2002639_2003038_-

132 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|52	0.6771653543307087	0.9696969696969697	0.9694656488549618

2001632-2045943

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP014944

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information