CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP014942	Staphylococcus aureus strain FDA209P	9 crisprs	cas3,DEDDh,DinG,csa3,WYL	7	1	9	0
NZ_AP014943	Staphylococcus aureus strain FDA209P plasmid pFDA209P, complete sequence	0 crisprs	csa3	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP014942_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_1

144856-144937

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014942_1

>merge|NZ_AP014942|1|144856-144937|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_AP014942|1|1|144856-144937|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_000171645.1\|148735_149767_+\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NZ_AP014942.1\|WP_000197961.1\|147961_148723_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NZ_AP014942.1\|WP_000290396.1\|141613_143101_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143435
NZ_AP014942.1\|WP_001230676.1\|136980_137868_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	unknown	unknown	gnl\|CDD\|187543
NZ_AP014942.1\|WP_042727606.1\|137921_139184_+\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|223749
NZ_AP014942.1\|WP_001236999.1\|140803_141187_-\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291
NZ_AP014942.1\|WP_000356963.1\|145000_145204_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000480603.1\|140470_140797_-\|staphylobilin-forming-heme-oxygenase-IsdI	unknown	unknown	gnl\|CDD\|183968
NZ_AP014942.1\|WP_001013481.1\|143747_144707_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_AP014942.1\|WP_042727612.1\|153624_160800_+\|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|237108
NZ_AP014942.1\|WP_000826862.1\|151927_153178_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_AP014942.1\|WP_000706137.1\|150516_151542_+\|NAD-dependent-formate-dehydrogenase	unknown	unknown	gnl\|CDD\|181041
NZ_AP014942.1\|WP_000239649.1\|134001_135207_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_001092004.1\|149983_150343_+\|DUF2294-domain-containing-protein	unknown	unknown	gnl\|CDD\|227896
NZ_AP014942.1\|WP_000590860.1\|146236_146977_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_AP014942.1\|WP_000171919.1\|145382_145895_+\|DUF4242-domain-containing-protein	unknown	unknown	gnl\|CDD\|379428
NZ_AP014942.1\|WP_000826655.1\|146990_147965_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270271
NZ_AP014942.1\|WP_000723455.1\|139260_140406_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|223458
NZ_AP014942.1\|WP_001291017.1\|135207_136413_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340825
NZ_AP014942.1\|WP_000825098.1\|136423_136981_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|225059

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_000171645.1\|148735_149767_+\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.67474e-20
NZ_AP014942.1\|WP_000197961.1\|147961_148723_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.22607e-73
NZ_AP014942.1\|WP_000290396.1\|141613_143101_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NZ_AP014942.1\|WP_001230676.1\|136980_137868_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	gnl\|CDD\|187543	cd05232, UDP_G4E_4_SDR_e, UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of bacterial proteins, and includes the Staphylococcus aureus capsular polysaccharide Cap5N, which may have a role in the synthesis of UDP-N-acetyl-d-fucosamine. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	8.67203e-118
NZ_AP014942.1\|WP_042727606.1\|137921_139184_+\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_AP014942.1\|WP_001236999.1\|140803_141187_-\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	7.54946e-41
NZ_AP014942.1\|WP_001013481.1\|143747_144707_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	3.08716e-108
NZ_AP014942.1\|WP_000480603.1\|140470_140797_-\|staphylobilin-forming-heme-oxygenase-IsdI	gnl\|CDD\|183968	PRK13313, PRK13313, staphylobilin-forming heme oxygenase IsdI.	1.40112e-64
NZ_AP014942.1\|WP_042727612.1\|153624_160800_+\|amino-acid-adenylation-domain-containing-protein	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_AP014942.1\|WP_000826862.1\|151927_153178_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.61322e-72
NZ_AP014942.1\|WP_000706137.1\|150516_151542_+\|NAD-dependent-formate-dehydrogenase	gnl\|CDD\|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
NZ_AP014942.1\|WP_001291017.1\|135207_136413_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	1.1999e-72
NZ_AP014942.1\|WP_001092004.1\|149983_150343_+\|DUF2294-domain-containing-protein	gnl\|CDD\|227896	COG5609, COG5609, Uncharacterized conserved protein [Function unknown].	6.06834e-49
NZ_AP014942.1\|WP_000590860.1\|146236_146977_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.48266e-112
NZ_AP014942.1\|WP_000171919.1\|145382_145895_+\|DUF4242-domain-containing-protein	gnl\|CDD\|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	2.56603e-26
NZ_AP014942.1\|WP_000723455.1\|139260_140406_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	0
NZ_AP014942.1\|WP_000826655.1\|146990_147965_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	5.03649e-50
NZ_AP014942.1\|WP_000825098.1\|136423_136981_+\|sugar-transferase	gnl\|CDD\|225059	COG2148, WcaJ, Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane].	3.08096e-87

>NZ_AP014942.1|WP_001013481.1|143747_144707_+|cation-transporter
MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVIEFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILAAFLNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQEDNINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRNAWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEGDDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT
>NZ_AP014942.1|WP_000290396.1|141613_143101_+|aldehyde-dehydrogenase-family-protein
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDKEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
>NZ_AP014942.1|WP_001236999.1|140803_141187_-|YbaN-family-protein
MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIAFSIYMVDVLAVRVGLIIMVIIQTAVLFTFVKTLPKSNHKIEE
>NZ_AP014942.1|WP_000480603.1|140470_140797_-|staphylobilin-forming-heme-oxygenase-IsdI
MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
>NZ_AP014942.1|WP_000723455.1|139260_140406_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDMLDSVLSIFDIQADHDLNIMQDQQTLAGLTANALAKLDSIINEEQPDMILVHGDTTTTFVGSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFENKDKERILITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIFKAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSYLVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIEDDEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRSDKPDEFVPLRHK
>NZ_AP014942.1|WP_042727606.1|137921_139184_+|nucleotide-sugar-dehydrogenase
MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEIYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAGKRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAIDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVIFDTKNVVKSSFEDVSYYNYGNIFNFIDK
>NZ_AP014942.1|WP_001230676.1|136980_137868_+|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN
MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSFKDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKAEDVKQFIFMSTMAVYGKEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCPGNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTSSVMYEIRRQSHRKTVLINMPSMLNKYFNKLSVFRKLFGNLIYSNTLYENNNALEVIPGKMSLVIADIMDETTTKDKA
>NZ_AP014942.1|WP_000825098.1|136423_136981_+|sugar-transferase
MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPTINNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEMSIVGPRPALYNQYELIEKRTKANVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTHQSMMLDMYIIYKTIKNIVTSEGVHH
>NZ_AP014942.1|WP_001291017.1|135207_136413_+|glycosyltransferase-family-4-protein
MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGWPYEYSNHKQVSKTEMHRGIRIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKYDQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYINRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKAYREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDHRIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKALVLIMDKQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREINTMKYYNLLK
>NZ_AP014942.1|WP_000239649.1|134001_135207_+|hypothetical-protein
MVKKVFIMDSVKTIIGTLLIALGLQFLAYPIINQRVGNEAFGSILTIYTIITITSVVLGNTLNNIRLINMNLYKSNHYYWKFVSILLISILIESIALIIVFLYFFNLNTIDIIFLILLNILMCLRIYLNVFFRMTLKYNQILYIALIQFLGLLIGLFLYYLTQNWIVCFITSELFATIYTLVKLRGLTIGEYQSEDNNVVKDYVMLLSTNSLNNLNLYLDRLILLPIIGGTAVTISFLSTFIGKMLATFLYPINNVVLSYISVNESDNIKKQYLKTNLFAIAALCLVMIICYPITIIIVSLLYNIDSSLYSKFIILGNIGVLFNAVSIMIQTLNTKHASITLQANYMTLHTITFIFITILMTIAFGLNGFFWTTLFSNIIKYVILNIIGLKSKFINKKDVD
>NZ_AP014942.1|WP_000356963.1|145000_145204_-|hypothetical-protein
MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILKPKDVVLDVDSIKEIDENHLNDAT
>NZ_AP014942.1|WP_000171919.1|145382_145895_+|DUF4242-domain-containing-protein
MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENLTHGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIPEGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAVDTPIDGIEKL
>NZ_AP014942.1|WP_000590860.1|146236_146977_+|ABC-transporter-ATP-binding-protein
MIKIQQLQHHFGSLKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRNDSHLLKIRNEIMETFALNHHQVEPEYYL
>NZ_AP014942.1|WP_000826655.1|146990_147965_+|ABC-transporter-substrate-binding-protein
MKRLSIIVIIGIFIIIGCDWQRTSKEPSKNAQNQQVIKIGYLPITHSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQKGSNIKAVALGHHEGNVIMGQKGMHLNEFNNNGDDYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS
>NZ_AP014942.1|WP_000197961.1|147961_148723_+|ABC-transporter-permease
MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVGKSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLIRPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLNLTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLNLEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE
>NZ_AP014942.1|WP_000171645.1|148735_149767_+|acyl-CoA/acyl-ACP-dehydrogenase
MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALRKNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLSNPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFILRANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQIPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTSHLSELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHLGKLEAELKG
>NZ_AP014942.1|WP_001092004.1|149983_150343_+|DUF2294-domain-containing-protein
MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAHMTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDIDLNDDEVISIFVFDKSIE
>NZ_AP014942.1|WP_000706137.1|150516_151542_+|NAD-dependent-formate-dehydrogenase
MKIVALFPEAVEGQENQLLNTKKALGLKTFLEERGHEFIILADNGEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNIGVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIGIFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSTSDAITIHAPLTPETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAPADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIASKSYTAK
>NZ_AP014942.1|WP_000826862.1|151927_153178_+|MFS-transporter
MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGIYLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFCVAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEIIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMFIVLTIGASMLVAGVFGGQKQVNTN
>NZ_AP014942.1|WP_042727612.1|153624_160800_+|amino-acid-adenylation-domain-containing-protein
MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMYALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELSTYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTRQHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDDMTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQRFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLADIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTERDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDLAHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDPNYPSDRQEYILKDVTPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNPKGTLIPHRGIVRLVHQNHYVPLNEETTILLSGTIAFDAATFEIYGTLLNGGKLIVAKKEQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVDLLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCGVGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLYRKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNKIKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHLLCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFELAQAIAKVQEQNYEVIPETIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSELNVAQLRQAVQRLIARHEILRTQYIVVDDEVRQRIVADVAVDFEEVNTHFTDEQEIMRQFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLLPLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFTMNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQMLGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRNPLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYIINIEYNTDLYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGNKSIISYFNEAVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFTERSFEMIAAMLATVKVGASYIPIDIDFPKKRQGAILEDAKVTAVMSYGVEIETTLPVIQLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLLNLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPAQLQQLINKHRVTVASIPLQMCSVMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPSESTVITSYWSHHCGDLIPEMIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAIGYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELDEIENAILAIRGISDCVVTVSHFDTHDILNAYYVGEQQMEQDLKQYLNDHLPKYMIPKTITHIDCMPLTTNDKVDTTRLPNPSPIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVGVDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMHQNQQSLVALPDNLSELQKIVMSRYNLGVLEDSLSHRPLGNTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIAWYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHAGARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTNRFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMPVKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMNHISEKWPTITNNWLYHWAQYIKTIFNK

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Crispr_ID: NZ_AP014942_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_2

268101-268241

Orphan

Consensus_repeat	Method
GGGCCCCAACACAAAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014942_2

>merge|NZ_AP014942|2|268101-268241|CRISPRCasFinder
GGGCCCCAACACAAAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGGCGGAAAGTCAGCATACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGG

>NZ_AP014942|2|2|268101-268241|CRISPRCasFinder
GGGCCCCAACACAAAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGG	CGGAAAGTCAGCATACAATAATGTGCAAGTTGGCG
GGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_042727591.1\|271977_272976_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_AP014942.1\|WP_001789860.1\|269271_269406_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000570077.1\|277389_278049_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_AP014942.1\|WP_000645454.1\|262829_263570_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
NZ_AP014942.1\|WP_000337372.1\|275069_276062_+\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NZ_AP014942.1\|WP_042727596.1\|260153_260828_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_AP014942.1\|WP_000610203.1\|255520_256546_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176199
NZ_AP014942.1\|WP_001066543.1\|273459_274836_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_AP014942.1\|WP_000066933.1\|265780_266572_+\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225101
NZ_AP014942.1\|WP_000736795.1\|276387_277338_+\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|366703
NZ_AP014942.1\|WP_000031267.1\|268491_269253_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_AP014942.1\|WP_000975368.1\|258288_260010_+\|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|376098
NZ_AP014942.1\|WP_000240920.1\|256567_258256_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NZ_AP014942.1\|WP_042727592.1\|270445_270850_-\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NZ_AP014942.1\|WP_000607067.1\|264118_264820_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NZ_AP014942.1\|WP_000922332.1\|264927_265632_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_AP014942.1\|WP_000182745.1\|269503_270418_-\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_AP014942.1\|WP_001792906.1\|263682_264126_+\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NZ_AP014942.1\|WP_042727594.1\|266587_268024_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
NZ_AP014942.1\|WP_000029204.1\|270864_271746_-\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_042727591.1\|271977_272976_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.99368e-99
NZ_AP014942.1\|WP_000337372.1\|275069_276062_+\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	1.22357e-151
NZ_AP014942.1\|WP_000570077.1\|277389_278049_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.07951e-65
NZ_AP014942.1\|WP_000645454.1\|262829_263570_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	9.61135e-152
NZ_AP014942.1\|WP_042727596.1\|260153_260828_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	8.44414e-154
NZ_AP014942.1\|WP_000610203.1\|255520_256546_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176199	cd08237, ribitol-5-phosphate_DH, ribitol-5-phosphate dehydrogenase. NAD-linked ribitol-5-phosphate dehydrogenase, a member of the MDR/zinc-dependent alcohol dehydrogenase-like family, oxidizes the phosphate ester of ribitol-5-phosphate to xylulose-5-phosphate of the pentose phosphate pathway. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	0
NZ_AP014942.1\|WP_001066543.1\|273459_274836_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.20037e-31
NZ_AP014942.1\|WP_000066933.1\|265780_266572_+\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	1.8481e-54
NZ_AP014942.1\|WP_000736795.1\|276387_277338_+\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	6.32575e-32
NZ_AP014942.1\|WP_000031267.1\|268491_269253_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.03413e-27
NZ_AP014942.1\|WP_000975368.1\|258288_260010_+\|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	4.75037e-35
NZ_AP014942.1\|WP_000240920.1\|256567_258256_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.42901e-119
NZ_AP014942.1\|WP_042727592.1\|270445_270850_-\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	2.3935e-68
NZ_AP014942.1\|WP_000607067.1\|264118_264820_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NZ_AP014942.1\|WP_000922332.1\|264927_265632_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.3822e-62
NZ_AP014942.1\|WP_000182745.1\|269503_270418_-\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	6.00205e-143
NZ_AP014942.1\|WP_001792906.1\|263682_264126_+\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	8.44339e-64
NZ_AP014942.1\|WP_042727594.1\|266587_268024_+\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
NZ_AP014942.1\|WP_000029204.1\|270864_271746_-\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	4.46997e-117

>NZ_AP014942.1|WP_042727594.1|266587_268024_+|6-phospho-beta-glucosidase
MTKLPQNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEGVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGDLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>NZ_AP014942.1|WP_000066933.1|265780_266572_+|PTS-glucose-transporter-subunit-IIA
MSNKYKEQAQDILTAVGGVENIVDATYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKNANVEESENTDNINSQDTSYTPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLVSMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDHVEAGQTLLQFDQQYIQQQGYNADVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>NZ_AP014942.1|WP_000922332.1|264927_265632_-|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHQSNFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEMATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDKLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>NZ_AP014942.1|WP_000607067.1|264118_264820_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>NZ_AP014942.1|WP_001792906.1|263682_264126_+|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>NZ_AP014942.1|WP_000645454.1|262829_263570_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSANAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPTYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NZ_AP014942.1|WP_042727596.1|260153_260828_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGKVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NZ_AP014942.1|WP_000975368.1|258288_260010_+|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase
MMKFSVIVPTYNSEKYMTELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>NZ_AP014942.1|WP_000240920.1|256567_258256_+|CDP-glycerol-glycerophosphotransferase-family-protein
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS
>NZ_AP014942.1|WP_000610203.1|255520_256546_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MINQVYQLVAPRQFEVTYNNVDIYSDYVIVRPLYMSICAADQRYYTGSRDENVLSQKLPMSLIHEGVGEVVFDSKGVFNKGTKVVMVPNTPTEKDDVIAENYLKSSYFRSSGHDGFMQDFVLLNHDRAVPLPDDIDLSIISYTELVTVSLHAIRRFEKKSISNKNTFGIWGDGNLGYITAILLRKLYPESKIYVFGKTDYKLSHFSFVDDVFFINKIPEGLTFDHAFECVGGRGSQSAINQMIDYISPEGSIALLGVSEFPVEVNTRLVLEKGLTLIGSSRSGSKDFQDVVDLYIQYPDIVDKLALLKGQEFEIATINDLTEAFEADLSTSWGKTVLKWIM
>NZ_AP014942.1|WP_000031267.1|268491_269253_-|class-I-SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPIAIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYNQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTIKIINNALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKED
>NZ_AP014942.1|WP_001789860.1|269271_269406_+|hypothetical-protein
MIIIIINIAYLYAIIWKLKRLQKIVTSFITKHESTSIGLVENYF
>NZ_AP014942.1|WP_000182745.1|269503_270418_-|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTTEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFIVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>NZ_AP014942.1|WP_042727592.1|270445_270850_-|D-ribose-pyranase
MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIGVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>NZ_AP014942.1|WP_000029204.1|270864_271746_-|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>NZ_AP014942.1|WP_042727591.1|271977_272976_-|LacI-family-DNA-binding-transcriptional-regulator
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSSLMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGINGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMMIVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>NZ_AP014942.1|WP_001066543.1|273459_274836_-|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGDHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSIICLSIFSITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTSLQPSQYIIAVVIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYTPSVAATVTFIVSIILMMLGSLSAYMIIPKTVKS
>NZ_AP014942.1|WP_000337372.1|275069_276062_+|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKADAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGHSVEVSFKEGEVVIKDNPIGVLTNHPDLNWHYSNLRQYINISPYPATAKLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNEIVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>NZ_AP014942.1|WP_000736795.1|276387_277338_+|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNSPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR
>NZ_AP014942.1|WP_000570077.1|277389_278049_-|ABC-transporter-ATP-binding-protein
MIEINNLSKRYRNKQIFNHLTMSFDSNRLTVLLGDNGAGKSTLLRMVAGIEKANDGTINYFGEKWNQRQIQNHIGYVPQDIALFEHMTVAENINFFKSLCKNPINDTTINEYLQQLNFDDTSAKVSTLSGGNKRKINILVGLLGQPRILILDEPTVGIDLKSRHDIHQLLNIMKSKCLIILTTHHLDEVEALADDIKLIGQDPFYQHVLEDKQWAYTYY

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Crispr_ID: NZ_AP014942_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_3

696256-696354

Orphan

Consensus_repeat	Method
AAGAGCCCCTAATTAATAAATTAAAAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014942_3

>merge|NZ_AP014942|3|696256-696354|CRISPRCasFinder
AAGAGCCCCTAATTAATAAATTAAAAGGGGACAAAGGAATACAGTTGGATGCTAACGCACCAACTGCATAAGAGCCCCTAATTAATAAATTAAAAGGGG

>NZ_AP014942|3|3|696256-696354|CRISPRCasFinder
AAGAGCCCCTAATTAATAAATTAAAAGGGG	ACAAAGGAATACAGTTGGATGCTAACGCACCAACTGCAT
AAGAGCCCCTAATTAATAAATTAAAAGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_000532966.1\|693002_693719_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
NZ_AP014942.1\|WP_000638621.1\|700407_700950_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_AP014942.1\|WP_000733433.1\|699501_699891_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000865624.1\|694544_695189_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|225188
NZ_AP014942.1\|WP_001090985.1\|692453_692813_+\|HTH-type-transcriptional-regulator-SarX	unknown	unknown	gnl\|CDD\|130944
NZ_AP014942.1\|WP_000731641.1\|687658_688456_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_AP014942.1\|WP_000820892.1\|701045_701612_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
NZ_AP014942.1\|WP_000120367.1\|686062_687070_+\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
NZ_AP014942.1\|WP_001259679.1\|698991_699435_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_AP014942.1\|WP_000545116.1\|700028_700328_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_001789973.1\|694283_694400_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000842860.1\|698175_698865_-\|DUF1129-family-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000152582.1\|697588_698077_+\|DUF456-domain-containing-protein	unknown	unknown	gnl\|CDD\|225395
NZ_AP014942.1\|WP_000081602.1\|688816_689461_+\|Bax-inhibitor-1-family-protein	unknown	unknown	gnl\|CDD\|223742
NZ_AP014942.1\|WP_000148828.1\|701613_702072_-\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_AP014942.1\|WP_000687412.1\|695304_696171_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_AP014942.1\|WP_001129752.1\|690157_692308_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_AP014942.1\|WP_000833486.1\|693718_694192_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|226072
NZ_AP014942.1\|WP_000358498.1\|702074_702758_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
NZ_AP014942.1\|WP_000367063.1\|696371_697592_+\|sugar-efflux-transporter	unknown	unknown	gnl\|CDD\|341024

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_000532966.1\|693002_693719_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	8.8628e-136
NZ_AP014942.1\|WP_000638621.1\|700407_700950_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.26713e-28
NZ_AP014942.1\|WP_000865624.1\|694544_695189_+\|DUF402-domain-containing-protein	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	1.46792e-91
NZ_AP014942.1\|WP_001090985.1\|692453_692813_+\|HTH-type-transcriptional-regulator-SarX	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.54609e-22
NZ_AP014942.1\|WP_000731641.1\|687658_688456_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.44834e-40
NZ_AP014942.1\|WP_000820892.1\|701045_701612_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	1.24037e-61
NZ_AP014942.1\|WP_000120367.1\|686062_687070_+\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	1.90489e-104
NZ_AP014942.1\|WP_001259679.1\|698991_699435_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.77401e-13
NZ_AP014942.1\|WP_000152582.1\|697588_698077_+\|DUF456-domain-containing-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	4.76789e-44
NZ_AP014942.1\|WP_000081602.1\|688816_689461_+\|Bax-inhibitor-1-family-protein	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	1.16188e-32
NZ_AP014942.1\|WP_000148828.1\|701613_702072_-\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	1.18273e-77
NZ_AP014942.1\|WP_000687412.1\|695304_696171_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.04787e-39
NZ_AP014942.1\|WP_001129752.1\|690157_692308_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.12683e-20
NZ_AP014942.1\|WP_000833486.1\|693718_694192_+\|cupin-domain-containing-protein	gnl\|CDD\|226072	COG3542, COG3542, Uncharacterized conserved protein [Function unknown].	7.22926e-75
NZ_AP014942.1\|WP_000358498.1\|702074_702758_-\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.000491798
NZ_AP014942.1\|WP_000367063.1\|696371_697592_+\|sugar-efflux-transporter	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.30756e-101

>NZ_AP014942.1|WP_000687412.1|695304_696171_+|LysR-family-transcriptional-regulator
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
>NZ_AP014942.1|WP_000865624.1|694544_695189_+|DUF402-domain-containing-protein
MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDPLEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGNARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDFKGFQKKIMYCFNKINAKAQKNHQKPQNKTNIEKSKQIKPKQYNQTKNHQQQKKN
>NZ_AP014942.1|WP_001789973.1|694283_694400_+|hypothetical-protein
MLQLFLMKIALNDFENDKSVLFIFLKNHFYEEMCVLSN
>NZ_AP014942.1|WP_000833486.1|693718_694192_+|cupin-domain-containing-protein
MKSAEQWIDELQLESHPEGGFYRETIREVLKDGRRAPFSSIYFLLTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYTTATLGTDIQNGDVLQYVVPKGTIFASSIEISNTYSLVGCMCQPAFEFKQFELFKQSELITQYPHLKSVIEKYALK
>NZ_AP014942.1|WP_000532966.1|693002_693719_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
>NZ_AP014942.1|WP_001090985.1|692453_692813_+|HTH-type-transcriptional-regulator-SarX
MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
>NZ_AP014942.1|WP_001129752.1|690157_692308_+|helix-turn-helix-transcriptional-regulator
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINDIETTYFVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
>NZ_AP014942.1|WP_000081602.1|688816_689461_+|Bax-inhibitor-1-family-protein
MSQNTNHSYYHQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLPLSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDIFYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTIITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR
>NZ_AP014942.1|WP_000731641.1|687658_688456_-|LysM-peptidoglycan-binding-domain-containing-protein
MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNSSNTSPQAGSASSHTVQAGESLNIIASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
>NZ_AP014942.1|WP_000120367.1|686062_687070_+|inorganic-phosphate-transporter
MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKTAILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYGIPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFKVIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVEPQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLACLLFYILNLFF
>NZ_AP014942.1|WP_000367063.1|696371_697592_+|sugar-efflux-transporter
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDVIST
>NZ_AP014942.1|WP_000152582.1|697588_698077_+|DUF456-domain-containing-protein
MTIILWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHNQHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFGIIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALLIN
>NZ_AP014942.1|WP_000842860.1|698175_698865_-|DUF1129-family-protein
MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVLLIGIVSFLKGFLGFFMEKNGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIERNISKKHSHTFL
>NZ_AP014942.1|WP_001259679.1|698991_699435_+|GNAT-family-N-acetyltransferase
MRTLNKDEHNYIKQIANIHETLLSQVESNYKCTKLSIALRYEMICSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKRISSTIHKNNLPMISLNKDLGYQVSHVKMYKDID
>NZ_AP014942.1|WP_000733433.1|699501_699891_+|hypothetical-protein
MKKLIISIMAVMLFLTGCGKSQEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDEDKNKDKDKEASQDKQSKDQIKSSDKDNHKKPTSTDKDQKANDKHQS
>NZ_AP014942.1|WP_000545116.1|700028_700328_+|hypothetical-protein
MHEQDFRILEGQDITLPELGRELENITGRTIADSTGEIKRVIAHLPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK
>NZ_AP014942.1|WP_000638621.1|700407_700950_+|GNAT-family-N-acetyltransferase
MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRSELDMRTMDAVIKDYGIGLFAVEDKETHQWIGFIGLNYIPETSDYPFKELPLYEIGWRLLPEFWGKGLATEGAKATLKLAEQHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELPNLSKYHLLKRQVRYYINLRK
>NZ_AP014942.1|WP_000820892.1|701045_701612_-|TIGR00730-family-Rossman-fold-protein
MKRIAVYCGASKGHDPSYVQKAYDLGKYFAEQGYELVFGAGSIGIMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD
>NZ_AP014942.1|WP_000148828.1|701613_702072_-|YaiI/YqxD-family-protein
MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
>NZ_AP014942.1|WP_000358498.1|702074_702758_-|hypothetical-protein
MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKVASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKDADKMNKILQKNIEKRHKEEQKAREKNEIQRIKDMKKSQKYEEKAGLTPNKLDEKTEKKGDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQQNKENNTEA

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Crispr_ID: NZ_AP014942_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_4

749150-749232

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014942_4

>merge|NZ_AP014942|4|749150-749232|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>NZ_AP014942|4|4|749150-749232|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_000098285.1\|738273_740214_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NZ_AP014942.1\|WP_000022321.1\|736795_737800_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NZ_AP014942.1\|WP_042727549.1\|753232_754099_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_AP014942.1\|WP_000692521.1\|754899_755298_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NZ_AP014942.1\|WP_031797439.1\|750687_750789_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000525103.1\|740483_742367_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_AP014942.1\|WP_060829053.1\|750866_752372_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_AP014942.1\|WP_000562498.1\|757483_758455_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_AP014942.1\|WP_001790169.1\|735807_736014_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000499195.1\|758968_759124_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000429006.1\|749680_750598_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_AP014942.1\|WP_000930014.1\|752712_753213_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851
NZ_AP014942.1\|WP_000180991.1\|745351_746866_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_AP014942.1\|WP_000876318.1\|759162_760134_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NZ_AP014942.1\|WP_000197275.1\|748458_749001_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NZ_AP014942.1\|WP_000855505.1\|755260_757366_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NZ_AP014942.1\|WP_000983677.1\|742378_744160_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NZ_AP014942.1\|WP_042727613.1\|736101_736812_+\|allophanate-hydrolase-subunit-1	unknown	unknown	gnl\|CDD\|224960
NZ_AP014942.1\|WP_000589260.1\|744381_745359_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_AP014942.1\|WP_000663025.1\|747105_748164_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_000098285.1\|738273_740214_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NZ_AP014942.1\|WP_000022321.1\|736795_737800_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	3.65343e-143
NZ_AP014942.1\|WP_042727549.1\|753232_754099_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	2.58734e-10
NZ_AP014942.1\|WP_000692521.1\|754899_755298_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NZ_AP014942.1\|WP_000525103.1\|740483_742367_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_AP014942.1\|WP_060829053.1\|750866_752372_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	6.99441e-173
NZ_AP014942.1\|WP_000562498.1\|757483_758455_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NZ_AP014942.1\|WP_000429006.1\|749680_750598_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.55646e-79
NZ_AP014942.1\|WP_000930014.1\|752712_753213_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
NZ_AP014942.1\|WP_000180991.1\|745351_746866_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
NZ_AP014942.1\|WP_000876318.1\|759162_760134_+\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
NZ_AP014942.1\|WP_000197275.1\|748458_749001_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	1.69885e-107
NZ_AP014942.1\|WP_000855505.1\|755260_757366_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_AP014942.1\|WP_000983677.1\|742378_744160_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_AP014942.1\|WP_042727613.1\|736101_736812_+\|allophanate-hydrolase-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	6.58993e-93
NZ_AP014942.1\|WP_000589260.1\|744381_745359_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.80291e-155
NZ_AP014942.1\|WP_000663025.1\|747105_748164_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0

>NZ_AP014942.1|WP_000197275.1|748458_749001_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDVVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NZ_AP014942.1|WP_000663025.1|747105_748164_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPLHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NZ_AP014942.1|WP_000180991.1|745351_746866_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NZ_AP014942.1|WP_000589260.1|744381_745359_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQLLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NZ_AP014942.1|WP_000983677.1|742378_744160_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NZ_AP014942.1|WP_000525103.1|740483_742367_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKIIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQTVQAYADDQSDKLFKRMMDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NZ_AP014942.1|WP_000098285.1|738273_740214_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NZ_AP014942.1|WP_000022321.1|736795_737800_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRIGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NZ_AP014942.1|WP_042727613.1|736101_736812_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDLESLLKHYKIKLETFIELHSKAQYFVSIMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>NZ_AP014942.1|WP_001790169.1|735807_736014_+|hypothetical-protein
MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIATITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NZ_AP014942.1|WP_000429006.1|749680_750598_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NZ_AP014942.1|WP_031797439.1|750687_750789_+|hypothetical-protein
MVITDIDVYRVGRENIVIAVYIEHIKLLFILIS
>NZ_AP014942.1|WP_060829053.1|750866_752372_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNAAAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NZ_AP014942.1|WP_000930014.1|752712_753213_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NZ_AP014942.1|WP_042727549.1|753232_754099_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFIYKYPQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NZ_AP014942.1|WP_000692521.1|754899_755298_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NZ_AP014942.1|WP_000855505.1|755260_757366_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NZ_AP014942.1|WP_000562498.1|757483_758455_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NZ_AP014942.1|WP_000499195.1|758968_759124_+|hypothetical-protein
MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNATINEKYYQ
>NZ_AP014942.1|WP_000876318.1|759162_760134_+|ABC-transporter-permease
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

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Crispr_ID: NZ_AP014942_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_5

795667-795749

Unclear

Consensus_repeat	Method
CCAACTTGCATTGTCTGTAGAAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014942_5

>merge|NZ_AP014942|5|795667-795749|CRISPRCasFinder
CCAACTTGCATTGTCTGTAGAAATTCTTTTCGAAATTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGTCTGTAGAAATT

>NZ_AP014942|5|5|795667-795749|CRISPRCasFinder
CCAACTTGCATTGTCTGTAGAAATT	CTTTTCGAAATTCTCTGTGTTGGGGCCCACACC
CCAACTTGCATTGTCTGTAGAAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_000638419.1\|784565_784802_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_AP014942.1\|WP_001248939.1\|796922_797918_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_AP014942.1\|WP_000369722.1\|796014_796926_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_AP014942.1\|WP_000057543.1\|792807_794247_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_AP014942.1\|WP_001224793.1\|792314_792800_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_AP014942.1\|WP_000070831.1\|801980_802610_+\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_AP014942.1\|WP_000513312.1\|791467_792307_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_AP014942.1\|WP_000538141.1\|783918_784569_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_AP014942.1\|WP_000229236.1\|785070_787056_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_AP014942.1\|WP_000749383.1\|782905_783745_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_AP014942.1\|WP_000134963.1\|794313_795249_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_AP014942.1\|WP_000958224.1\|790529_791462_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_AP014942.1\|WP_001049165.1\|799545_800133_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_AP014942.1\|WP_000279414.1\|804379_805390_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_AP014942.1\|WP_000006551.1\|798028_798973_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_AP014942.1\|WP_001260101.1\|806840_807602_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_AP014942.1\|WP_000662681.1\|787063_789910_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_AP014942.1\|WP_000816304.1\|800375_801278_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_AP014942.1\|WP_000654030.1\|803313_804327_+\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_AP014942.1\|WP_001074757.1\|805528_806719_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_000638419.1\|784565_784802_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_AP014942.1\|WP_001248939.1\|796922_797918_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_AP014942.1\|WP_000369722.1\|796014_796926_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_AP014942.1\|WP_000057543.1\|792807_794247_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_AP014942.1\|WP_001224793.1\|792314_792800_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_AP014942.1\|WP_000070831.1\|801980_802610_+\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.80381e-05
NZ_AP014942.1\|WP_000513312.1\|791467_792307_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.82832e-120
NZ_AP014942.1\|WP_000538141.1\|783918_784569_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_AP014942.1\|WP_000229236.1\|785070_787056_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_AP014942.1\|WP_000749383.1\|782905_783745_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
NZ_AP014942.1\|WP_000134963.1\|794313_795249_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_AP014942.1\|WP_000958224.1\|790529_791462_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_AP014942.1\|WP_001049165.1\|799545_800133_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_AP014942.1\|WP_000279414.1\|804379_805390_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_AP014942.1\|WP_000006551.1\|798028_798973_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_AP014942.1\|WP_001260101.1\|806840_807602_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.48635e-146
NZ_AP014942.1\|WP_000662681.1\|787063_789910_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_AP014942.1\|WP_000816304.1\|800375_801278_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
NZ_AP014942.1\|WP_000654030.1\|803313_804327_+\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
NZ_AP014942.1\|WP_001074757.1\|805528_806719_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0

>NZ_AP014942.1|WP_000134963.1|794313_795249_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_AP014942.1|WP_000057543.1|792807_794247_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_AP014942.1|WP_001224793.1|792314_792800_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_AP014942.1|WP_000513312.1|791467_792307_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEKLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_AP014942.1|WP_000958224.1|790529_791462_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_AP014942.1|WP_000662681.1|787063_789910_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_AP014942.1|WP_000229236.1|785070_787056_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQIRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_AP014942.1|WP_000638419.1|784565_784802_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_AP014942.1|WP_000538141.1|783918_784569_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_AP014942.1|WP_000749383.1|782905_783745_+|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_AP014942.1|WP_000369722.1|796014_796926_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_AP014942.1|WP_001248939.1|796922_797918_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_AP014942.1|WP_000006551.1|798028_798973_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_AP014942.1|WP_001049165.1|799545_800133_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_AP014942.1|WP_000816304.1|800375_801278_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_AP014942.1|WP_000070831.1|801980_802610_+|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDNASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_AP014942.1|WP_000654030.1|803313_804327_+|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_AP014942.1|WP_000279414.1|804379_805390_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_AP014942.1|WP_001074757.1|805528_806719_+|phosphoglycerate-kinase
MAKKIVSDLNLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_AP014942.1|WP_001260101.1|806840_807602_+|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTVVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSENQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: NZ_AP014942_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_6

838807-838888

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014942_6

>merge|NZ_AP014942|6|838807-838888|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_AP014942|6|6|838807-838888|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_000255553.1\|832564_833182_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_AP014942.1\|WP_001033317.1\|845292_846021_-\|staphylococcal-enterotoxin-type-Q	unknown	unknown	gnl\|CDD\|280949
NZ_AP014942.1\|WP_001140697.1\|831910_832492_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_AP014942.1\|WP_000571218.1\|840537_841563_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_AP014942.1\|WP_001063624.1\|847079_847292_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_AP014942.1\|WP_001190695.1\|836287_836608_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_AP014942.1\|WP_000732326.1\|842268_843090_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_AP014942.1\|WP_000589549.1\|836751_837108_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_AP014942.1\|WP_000142630.1\|846195_846930_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_AP014942.1\|WP_001018962.1\|839612_839999_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_AP014942.1\|WP_000422908.1\|835598_836138_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_AP014942.1\|WP_000290490.1\|837265_837646_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_AP014942.1\|WP_042727546.1\|844540_845269_-\|staphylococcal-enterotoxin-type-K	unknown	unknown	gnl\|CDD\|280949
NZ_AP014942.1\|WP_000569884.1\|833336_833831_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_AP014942.1\|WP_000520233.1\|841555_842251_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_AP014942.1\|WP_000974460.1\|834229_834652_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_AP014942.1\|WP_000264181.1\|843232_844453_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_AP014942.1\|WP_000932212.1\|837824_838703_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_AP014942.1\|WP_000150013.1\|834799_835516_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_AP014942.1\|WP_001065801.1\|839991_840288_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_000255553.1\|832564_833182_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.40612e-61
NZ_AP014942.1\|WP_001033317.1\|845292_846021_-\|staphylococcal-enterotoxin-type-Q	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	7.79999e-28
NZ_AP014942.1\|WP_001140697.1\|831910_832492_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.29633e-48
NZ_AP014942.1\|WP_000571218.1\|840537_841563_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_AP014942.1\|WP_001063624.1\|847079_847292_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	7.52525e-13
NZ_AP014942.1\|WP_001190695.1\|836287_836608_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_AP014942.1\|WP_000732326.1\|842268_843090_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NZ_AP014942.1\|WP_000589549.1\|836751_837108_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_AP014942.1\|WP_000142630.1\|846195_846930_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.1934e-12
NZ_AP014942.1\|WP_001018962.1\|839612_839999_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_AP014942.1\|WP_000422908.1\|835598_836138_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_AP014942.1\|WP_000290490.1\|837265_837646_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.28962e-69
NZ_AP014942.1\|WP_042727546.1\|844540_845269_-\|staphylococcal-enterotoxin-type-K	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	2.55336e-24
NZ_AP014942.1\|WP_000569884.1\|833336_833831_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_AP014942.1\|WP_000520233.1\|841555_842251_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_AP014942.1\|WP_000974460.1\|834229_834652_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_AP014942.1\|WP_000264181.1\|843232_844453_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.06701e-37
NZ_AP014942.1\|WP_000932212.1\|837824_838703_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.72543e-74
NZ_AP014942.1\|WP_000150013.1\|834799_835516_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	5.95463e-148
NZ_AP014942.1\|WP_001065801.1\|839991_840288_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14

>NZ_AP014942.1|WP_000932212.1|837824_838703_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQEHLKSLDADNEDIPFSGAFSIKFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_AP014942.1|WP_000290490.1|837265_837646_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSKMIGE
>NZ_AP014942.1|WP_000589549.1|836751_837108_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_AP014942.1|WP_001190695.1|836287_836608_-|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_AP014942.1|WP_000422908.1|835598_836138_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_AP014942.1|WP_000150013.1|834799_835516_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_AP014942.1|WP_000974460.1|834229_834652_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_AP014942.1|WP_000569884.1|833336_833831_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_AP014942.1|WP_000255553.1|832564_833182_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLIF
>NZ_AP014942.1|WP_001140697.1|831910_832492_+|histidine-phosphatase-family-protein
MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGLFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>NZ_AP014942.1|WP_001018962.1|839612_839999_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_AP014942.1|WP_001065801.1|839991_840288_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_AP014942.1|WP_000571218.1|840537_841563_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_AP014942.1|WP_000520233.1|841555_842251_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_AP014942.1|WP_000732326.1|842268_843090_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_AP014942.1|WP_000264181.1|843232_844453_-|site-specific-integrase
MWFEKFKNKNKETKYRYYEKYKDPLTNKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDKTPTTLKSLTFHAASDEWFQNYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDSKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINMKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQNEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQLKLG
>NZ_AP014942.1|WP_042727546.1|844540_845269_-|staphylococcal-enterotoxin-type-K
MKKLISILLINIIILGVSNNASAQGDIGIDNLRNFYTKKDFVDLKDVKDNDTPIANQLQFSNESYDLISESKDFNKFSNFKGKKLDVFGISYNGQCNTKYIYGGVTATNEYLDKSRNIPINIWINGNHKTISTNKVSTNKKLVTAQEIDVKLRKYLQEEYNIYGHNGTKKGEEYGHKSKFYSGFNIGKVTFHLNNNDTFSYGLFYTGDDGLPKSFLKIYEDNKTVESEKFHLDVDISYKETI
>NZ_AP014942.1|WP_001033317.1|845292_846021_-|staphylococcal-enterotoxin-type-Q
MNKIFRILTVSLFFFTFLIKNNLAYADVGVINLRNFYANYEPEKLQGVSSGNFSTSHQLEYIDGKYTLYSQFHNEYEAKRLKDHKVDIFGISYSGLCNTKYMYGGITLANQNLDKPRNIPINLWVNGKQNTISTDKVSTQKKEVTAQEIDIKLRKYLQNEYNIYGFNKTKKGQEYGYQSKFNSGFNKGKITFHLNNEPSFTYDLFYTGTGQAESFLKIYNDNKTIDAENFHLDVEISYEKTE
>NZ_AP014942.1|WP_000142630.1|846195_846930_-|helix-turn-helix-transcriptional-regulator
MTFGEILKKERVSWKLSVKELSTLSGVSQTYISKLENGKRNFPSLETIFNLLIGFKTHIEYKMGSESPFYEINNSYLDEILIMFINSSNSTISDRDPNELITQFNEYYDVTIKKKQNENSKIESDIFSNKIKLVKGTTKKEVIEKPYFDLNWLLTQNEYEVFFDRSFLLDNNFLNKKHFTEKDMYYYNVLNDNDLKTIKDLIVVFLLNKYNYIKNKDDFFNIFTNSEDDKTKRDALYKILYETD
>NZ_AP014942.1|WP_001063624.1|847079_847292_+|helix-turn-helix-transcriptional-regulator
MNNNLSLLMGKHRVTASKLSTVTGISRTSIHGLYHERTENPDTKTVMKLCEYFNITPNEFFGIIEKEGVK

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Crispr_ID: NZ_AP014942_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_7

1121488-1121674

Orphan

Consensus_repeat	Method
GGCGGGGCCCCAACATAGA	CRT

3 spacers

The CRISPR arrays of NZ_AP014942_7

>merge|NZ_AP014942|7|1121488-1121674|CRT
GGCGGGGCCCCAACATAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGTGGGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGTGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGA

>NZ_AP014942|7|1|1121488-1121674|CRT
GGCGGGGCCCCAACATAGA	GAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTG
GGGTGGGCCCCAACACAGA	AGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTT
GGCGGGGCCCCAACATAGT	GAAATTGGATTCCCAATTTCTACAGACAATGCAAGTT
GGCGGGGCCCCAACATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_001245802.1\|1130415_1130604_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NZ_AP014942.1\|WP_000791581.1\|1116261_1116759_+\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NZ_AP014942.1\|WP_000231632.1\|1118662_1118896_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_001032816.1\|1117855_1118041_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000739570.1\|1114424_1114826_-\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NZ_AP014942.1\|WP_000584398.1\|1115496_1116003_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000149429.1\|1128687_1128915_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000793612.1\|1124695_1125697_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_AP014942.1\|WP_000432077.1\|1126823_1128380_+\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_AP014942.1\|WP_000765708.1\|1121004_1121151_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_001063559.1\|1122712_1123438_-\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_AP014942.1\|WP_001802045.1\|1121107_1121332_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000147103.1\|1131706_1131841_+\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_AP014942.1\|WP_001239285.1\|1129219_1130167_-\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NZ_AP014942.1\|WP_000739208.1\|1113725_1114055_+\|complement-convertase-inhibitor-Ecb	unknown	unknown	gnl\|CDD\|289007
NZ_AP014942.1\|WP_000669528.1\|1116909_1117260_+\|complement-inhibitor-SCIN-family-protein	unknown	unknown	gnl\|CDD\|371594
NZ_AP014942.1\|WP_000398672.1\|1131515_1131650_+\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_AP014942.1\|WP_000857485.1\|1119372_1120332_-\|alpha-hemolysin	unknown	unknown	gnl\|CDD\|273388
NZ_AP014942.1\|WP_042727635.1\|1125719_1126652_+\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_AP014942.1\|WP_000739523.1\|1123532_1124258_-\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_001245802.1\|1130415_1130604_+\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
NZ_AP014942.1\|WP_000791581.1\|1116261_1116759_+\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.84801e-27
NZ_AP014942.1\|WP_000147103.1\|1131706_1131841_+\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	4.87929e-13
NZ_AP014942.1\|WP_000739570.1\|1114424_1114826_-\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	5.2726e-76
NZ_AP014942.1\|WP_000793612.1\|1124695_1125697_+\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_AP014942.1\|WP_000432077.1\|1126823_1128380_+\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_AP014942.1\|WP_000739523.1\|1123532_1124258_-\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
NZ_AP014942.1\|WP_001063559.1\|1122712_1123438_-\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
NZ_AP014942.1\|WP_000739208.1\|1113725_1114055_+\|complement-convertase-inhibitor-Ecb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.51827e-21
NZ_AP014942.1\|WP_000669528.1\|1116909_1117260_+\|complement-inhibitor-SCIN-family-protein	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	8.46865e-41
NZ_AP014942.1\|WP_000398672.1\|1131515_1131650_+\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
NZ_AP014942.1\|WP_000857485.1\|1119372_1120332_-\|alpha-hemolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.4958e-141
NZ_AP014942.1\|WP_042727635.1\|1125719_1126652_+\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_AP014942.1\|WP_001239285.1\|1129219_1130167_-\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	7.44089e-84

>NZ_AP014942.1|WP_001802045.1|1121107_1121332_+|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_AP014942.1|WP_000765708.1|1121004_1121151_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_AP014942.1|WP_000857485.1|1119372_1120332_-|alpha-hemolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
>NZ_AP014942.1|WP_000231632.1|1118662_1118896_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_AP014942.1|WP_001032816.1|1117855_1118041_-|hypothetical-protein
MNKHINKKASKLLEDYKKVQQRKSEETDKGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_AP014942.1|WP_000669528.1|1116909_1117260_+|complement-inhibitor-SCIN-family-protein
MKFKKYILTGTLALLLSSTAIATIEGNKADASSKKDYIIQSEFHDKRIAEELKSLLDQSYVNDLAAGSLNPYYKRTIMMNQYRAKAALKSNNFAKMAEAKVALENIYKEIDEIINR
>NZ_AP014942.1|WP_000791581.1|1116261_1116759_+|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVR
>NZ_AP014942.1|WP_000584398.1|1115496_1116003_+|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_AP014942.1|WP_000739570.1|1114424_1114826_-|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLSTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSIYWD
>NZ_AP014942.1|WP_000739208.1|1113725_1114055_+|complement-convertase-inhibitor-Ecb
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNAETVKKYNEYQTNFKKQVNKKVVDAQKAVNLFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK
>NZ_AP014942.1|WP_001063559.1|1122712_1123438_-|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_AP014942.1|WP_000739523.1|1123532_1124258_-|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NZ_AP014942.1|WP_000793612.1|1124695_1125697_+|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDNIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_AP014942.1|WP_042727635.1|1125719_1126652_+|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVIIHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NZ_AP014942.1|WP_000432077.1|1126823_1128380_+|YfcC-family-protein
MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>NZ_AP014942.1|WP_000149429.1|1128687_1128915_+|hypothetical-protein
MTHLTKVLVTLTGICVVLLFSKYFVAYANMVFDWNLRWYMLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NZ_AP014942.1|WP_001239285.1|1129219_1130167_-|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>NZ_AP014942.1|WP_001245802.1|1130415_1130604_+|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>NZ_AP014942.1|WP_000398672.1|1131515_1131650_+|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF
>NZ_AP014942.1|WP_000147103.1|1131706_1131841_+|beta-class-phenol-soluble-modulin
MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF

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Click the colored protein region to show detailed information

Crispr_ID: NZ_AP014942_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_8

1734097-1734183

Orphan

Consensus_repeat	Method
ATGCAAGTTGGGGTGGGGCCCCAACATAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014942_8

>merge|NZ_AP014942|8|1734097-1734183|CRISPRCasFinder
ATGCAAGTTGGGGTGGGGCCCCAACATAGAGAATTTCGAAAAGAAATTCTACAGACCATGCAAGTTGGGGTGGGCCCCAACATAGAA

>NZ_AP014942|8|7|1734097-1734183|CRISPRCasFinder
ATGCAAGTTGGGGTGGGGCCCCAACATAGA	GAATTTCGAAAAGAAATTCTACAGACC
ATGCAAGTTGGGGTGGGCCCCAACATAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_000040063.1\|1740734_1741937_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_AP014942.1\|WP_000123164.1\|1716498_1717767_-\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NZ_AP014942.1\|WP_001836688.1\|1729662_1732860_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|223660
NZ_AP014942.1\|WP_060829070.1\|1739988_1740489_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_AP014942.1\|WP_001789984.1\|1738507_1738606_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000277602.1\|1735776_1736190_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_AP014942.1\|WP_000883648.1\|1725987_1726932_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NZ_AP014942.1\|WP_000058389.1\|1727983_1729213_-\|NAD-dependent-malic-enzyme-4	unknown	unknown	gnl\|CDD\|235976
NZ_AP014942.1\|WP_000471571.1\|1726931_1727789_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_AP014942.1\|WP_000136253.1\|1743094_1743589_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_AP014942.1\|WP_000689998.1\|1738729_1739848_-\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_AP014942.1\|WP_000717561.1\|1724750_1725719_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_AP014942.1\|WP_001232648.1\|1722971_1724729_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NZ_AP014942.1\|WP_000829167.1\|1717815_1718937_-\|citrate-synthase	unknown	unknown	gnl\|CDD\|184468
NZ_AP014942.1\|WP_000626076.1\|1732880_1733822_-\|pApA-hydrolase-Pde2	unknown	unknown	gnl\|CDD\|223691
NZ_AP014942.1\|WP_000840584.1\|1742024_1742972_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|223897
NZ_AP014942.1\|WP_000160435.1\|1734273_1735572_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_AP014942.1\|WP_000818525.1\|1719285_1720647_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_AP014942.1\|WP_000161674.1\|1737358_1738414_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NZ_AP014942.1\|WP_000777190.1\|1736494_1737184_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_000040063.1\|1740734_1741937_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_AP014942.1\|WP_000123164.1\|1716498_1717767_-\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NZ_AP014942.1\|WP_001836688.1\|1729662_1732860_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|223660	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].	0
NZ_AP014942.1\|WP_060829070.1\|1739988_1740489_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	3.01594e-33
NZ_AP014942.1\|WP_000277602.1\|1735776_1736190_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	6.00154e-19
NZ_AP014942.1\|WP_000883648.1\|1725987_1726932_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NZ_AP014942.1\|WP_000058389.1\|1727983_1729213_-\|NAD-dependent-malic-enzyme-4	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NZ_AP014942.1\|WP_000471571.1\|1726931_1727789_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_AP014942.1\|WP_000136253.1\|1743094_1743589_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	8.69777e-99
NZ_AP014942.1\|WP_000689998.1\|1738729_1739848_-\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_AP014942.1\|WP_000717561.1\|1724750_1725719_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_AP014942.1\|WP_001232648.1\|1722971_1724729_-\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NZ_AP014942.1\|WP_000829167.1\|1717815_1718937_-\|citrate-synthase	gnl\|CDD\|184468	PRK14035, PRK14035, citrate synthase; Provisional.	0
NZ_AP014942.1\|WP_000626076.1\|1732880_1733822_-\|pApA-hydrolase-Pde2	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	2.09048e-98
NZ_AP014942.1\|WP_000840584.1\|1742024_1742972_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	1.04193e-56
NZ_AP014942.1\|WP_000160435.1\|1734273_1735572_-\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_AP014942.1\|WP_000818525.1\|1719285_1720647_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_AP014942.1\|WP_000161674.1\|1737358_1738414_+\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	9.25455e-126
NZ_AP014942.1\|WP_000777190.1\|1736494_1737184_-\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	1.10209e-133

>NZ_AP014942.1|WP_000626076.1|1732880_1733822_-|pApA-hydrolase-Pde2
MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGRKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVDSWDEFEQLATALRTKLN
>NZ_AP014942.1|WP_001836688.1|1729662_1732860_-|DNA-polymerase-III-subunit-alpha
MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDACIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKKVGDQHRDIVQVFETHNDTYMDHLSISIQGRKHVWIQDVCYQTRQDADTISALAAIRDNTKLDLIHDQEDFGAHFLTEKEVNQLDINQEYLTQVDVIAQKCNAELKYHQSLLPQYETPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKKTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQKGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDHRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVMLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
>NZ_AP014942.1|WP_000058389.1|1727983_1729213_-|NAD-dependent-malic-enzyme-4
MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPCKDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGINGVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRGAIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMADNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIEVDPQDVYDKTMKLTDLQ
>NZ_AP014942.1|WP_000471571.1|1726931_1727789_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
>NZ_AP014942.1|WP_000883648.1|1725987_1726932_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDVEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
>NZ_AP014942.1|WP_000717561.1|1724750_1725719_-|6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
>NZ_AP014942.1|WP_001232648.1|1722971_1724729_-|pyruvate-kinase
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
>NZ_AP014942.1|WP_000818525.1|1719285_1720647_+|amino-acid-permease
MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILLTYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIGLIVVGFVMILFAFKTQFGHASFTNLYEHGIFAKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFASSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKNATYKLLGGKYMGYLIFVFFIFVFGLLFINVDTRRAIYFIPIWFILLAFMYLRYKRIAAKSNK
>NZ_AP014942.1|WP_000829167.1|1717815_1718937_-|citrate-synthase
MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYIAHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYMLRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSRQITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSRSAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK
>NZ_AP014942.1|WP_000123164.1|1716498_1717767_-|NADP-dependent-isocitrate-dehydrogenase
MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVEKEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK
>NZ_AP014942.1|WP_000160435.1|1734273_1735572_-|CBS-domain-containing-protein
MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDADKMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGAMELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVINFANEHDLPVLSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANRTGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMIWEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGITVEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHITVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV
>NZ_AP014942.1|WP_000277602.1|1735776_1736190_+|universal-stress-protein
MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQASIKAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEIVVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK
>NZ_AP014942.1|WP_000777190.1|1736494_1737184_-|metal-dependent-hydrolase
MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKVNFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
>NZ_AP014942.1|WP_000161674.1|1737358_1738414_+|aminopeptidase-P-family-protein
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLTSGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIILEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
>NZ_AP014942.1|WP_001789984.1|1738507_1738606_-|hypothetical-protein
MNDIDLIHYMLLMNIPAYVFLACLLHIAFRLG
>NZ_AP014942.1|WP_000689998.1|1738729_1739848_-|alanine-dehydrogenase
MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
>NZ_AP014942.1|WP_060829070.1|1739988_1740489_+|universal-stress-protein
MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPYDVLVVRTEELPADFQPQVATTQLREKYQN
>NZ_AP014942.1|WP_000040063.1|1740734_1741937_-|acetate-kinase
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
>NZ_AP014942.1|WP_000840584.1|1742024_1742972_-|class-I-SAM-dependent-methyltransferase
MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTNERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEELHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQDAIMPLPLEEIDIVIGDFPVGYYPIDERSKEFKLGFEEGHSYSHYLLIEQAINVLKDAGYAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSGETKPVEVLLANIPDFKNPSQFQGFMTELNQWMDTNRPKK
>NZ_AP014942.1|WP_000136253.1|1743094_1743589_-|thiol-peroxidase
MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSDASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI

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Crispr_ID: NZ_AP014942_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014942_9

2180496-2180652

Orphan

Consensus_repeat	Method
CCCCTACTTTTCAACTTTAGTTGTTAGGGGCTCTTATGCAG	PILER-CR

2 spacers

csa3

The CRISPR arrays of NZ_AP014942_9

>merge|NZ_AP014942|9|2180496-2180652|PILER-CR
CTTACAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTATTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTCTTATGCAG

>NZ_AP014942|9|1|2180496-2180652|PILER-CR
CTTACAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGC	GTAGCATCCAACTGTATTCCTCTAT
TTTTCAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTA	GCGCAGGCGCTCCTAC
TTTTCAACTTTAGTTGTTAGGGGCTCTTATGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014942.1\|WP_000334465.1\|2186274_2188080_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_AP014942.1\|WP_031797709.1\|2181407_2181485_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000123402.1\|2173324_2174698_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_AP014942.1\|WP_000019744.1\|2178145_2179126_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_AP014942.1\|WP_060829078.1\|2177006_2177672_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_AP014942.1\|WP_000648723.1\|2192911_2194018_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_AP014942.1\|WP_000115560.1\|2182190_2183327_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_AP014942.1\|WP_001123303.1\|2172454_2172868_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_AP014942.1\|WP_000160304.1\|2170980_2171691_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_AP014942.1\|WP_001292149.1\|2192477_2192912_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_AP014942.1\|WP_000927341.1\|2190333_2192466_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_AP014942.1\|WP_000808817.1\|2175371_2175602_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000220900.1\|2180748_2180841_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000003759.1\|2177823_2178144_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_AP014942.1\|WP_060829079.1\|2185260_2186043_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_AP014942.1\|WP_001127960.1\|2175632_2176571_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_AP014942.1\|WP_000495669.1\|2179391_2180483_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014942.1\|WP_000083807.1\|2188760_2190299_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_AP014942.1\|WP_000370945.1\|2184335_2185193_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_AP014942.1\|WP_000070866.1\|2171811_2172255_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854

Protein	Function_ID	Function_description	E-value
NZ_AP014942.1\|WP_000334465.1\|2186274_2188080_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_AP014942.1\|WP_000123402.1\|2173324_2174698_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_AP014942.1\|WP_000019744.1\|2178145_2179126_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
NZ_AP014942.1\|WP_060829078.1\|2177006_2177672_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.80456e-47
NZ_AP014942.1\|WP_000648723.1\|2192911_2194018_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_AP014942.1\|WP_000115560.1\|2182190_2183327_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	4.78584e-06
NZ_AP014942.1\|WP_001123303.1\|2172454_2172868_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_AP014942.1\|WP_000160304.1\|2170980_2171691_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_AP014942.1\|WP_001292149.1\|2192477_2192912_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_AP014942.1\|WP_000927341.1\|2190333_2192466_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.36261e-68
NZ_AP014942.1\|WP_000370945.1\|2184335_2185193_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.28483e-59
NZ_AP014942.1\|WP_000003759.1\|2177823_2178144_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_AP014942.1\|WP_060829079.1\|2185260_2186043_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	7.55858e-107
NZ_AP014942.1\|WP_001127960.1\|2175632_2176571_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_AP014942.1\|WP_000083807.1\|2188760_2190299_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_AP014942.1\|WP_000070866.1\|2171811_2172255_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67

>NZ_AP014942.1|WP_000495669.1|2179391_2180483_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENGKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_AP014942.1|WP_000019744.1|2178145_2179126_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_AP014942.1|WP_000003759.1|2177823_2178144_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_AP014942.1|WP_060829078.1|2177006_2177672_-|SDR-family-oxidoreductase
MNILVIGANGGVGLLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NZ_AP014942.1|WP_001127960.1|2175632_2176571_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_AP014942.1|WP_000808817.1|2175371_2175602_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_AP014942.1|WP_000123402.1|2173324_2174698_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_AP014942.1|WP_001123303.1|2172454_2172868_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_AP014942.1|WP_000070866.1|2171811_2172255_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_AP014942.1|WP_000160304.1|2170980_2171691_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_AP014942.1|WP_000220900.1|2180748_2180841_+|hypothetical-protein
MTYGSIIAIVCALFVIFFIPYMEKNNKKKK
>NZ_AP014942.1|WP_031797709.1|2181407_2181485_-|hypothetical-protein
MLLLERSSMSVFEMLIIVLTIIGLV
>NZ_AP014942.1|WP_000115560.1|2182190_2183327_-|SAP-domain-containing-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIFKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKTDVKDYDNARKYSNVYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASDLYERLIYNKNLSNNIIFELFKKDTQDYSDLEEQLIEKFINYVVSYVKKEGWSNTLLELSKMLENGYTIDKEEFKKEDEYLSRYIITDINYLKNLESKIGVAIDSRNGEIHLVLDDDSLDKLIKNQKNDNEV
>NZ_AP014942.1|WP_000370945.1|2184335_2185193_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGIHQDETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_AP014942.1|WP_060829079.1|2185260_2186043_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQESERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_AP014942.1|WP_000334465.1|2186274_2188080_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_AP014942.1|WP_000083807.1|2188760_2190299_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_AP014942.1|WP_000927341.1|2190333_2192466_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSSYLTVNPLLPDSDISYVAQFLNTKSTFQEMHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSNLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRSKFLERIKKQFI
>NZ_AP014942.1|WP_001292149.1|2192477_2192912_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_AP014942.1|WP_000648723.1|2192911_2194018_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP014942_1	1.1\|144880\|34\|NZ_AP014942\|CRISPRCasFinder	144880-144913	34	NZ_AP014942.1	1429100-1429133	0	1.0
NZ_AP014942_5	5.1\|795692\|33\|NZ_AP014942\|CRISPRCasFinder	795692-795724	33	NZ_AP014942.1	1942283-1942315	0	1.0
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	2297317-2297353	0	1.0
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	348042-348078	0	1.0
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	802880-802916	0	1.0
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	1019123-1019159	0	1.0
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	1474141-1474177	0	1.0
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	1613737-1613773	0	1.0
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	1940917-1940953	0	1.0
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	2331631-2331667	0	1.0
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	749138-749174	0	1.0
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	1429080-1429116	0	1.0
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	1474197-1474233	0	1.0
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	1942318-1942354	0	1.0
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	1942377-1942413	0	1.0
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	2331687-2331723	0	1.0
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	2734216-2734252	0	1.0
NZ_AP014942_1	1.1\|144880\|34\|NZ_AP014942\|CRISPRCasFinder	144880-144913	34	NZ_AP014942.1	1205738-1205771	1	0.971
NZ_AP014942_1	1.1\|144880\|34\|NZ_AP014942\|CRISPRCasFinder	144880-144913	34	NZ_AP014942.1	2619715-2619748	1	0.971
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	839190-839224	1	0.971
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	839246-839280	1	0.971
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	1205817-1205851	1	0.971
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	2297369-2297403	1	0.971
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	2461883-2461917	1	0.971
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	2734100-2734134	1	0.971
NZ_AP014942_6	6.1\|838831\|34\|NZ_AP014942\|CRISPRCasFinder	838831-838864	34	NZ_AP014942.1	1429100-1429133	1	0.971
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	1340100-1340136	1	0.973
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	2487210-2487246	1	0.973
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	2619675-2619711	1	0.973
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	1429138-1429174	1	0.973
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	2297373-2297409	1	0.973
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	2569085-2569121	1	0.973
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	795727-795763	1	0.973
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	1205755-1205791	1	0.973
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	2569029-2569065	1	0.973
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	2619732-2619768	1	0.973
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	2734160-2734196	1	0.973
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	758700-758734	2	0.943
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	1117601-1117635	2	0.943
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	1474147-1474181	2	0.943
NZ_AP014942_2	2.1\|268154\|35\|NZ_AP014942\|CRISPRCasFinder	268154-268188	35	NZ_AP014942.1	2331637-2331671	2	0.943
NZ_AP014942_6	6.1\|838831\|34\|NZ_AP014942\|CRISPRCasFinder	838831-838864	34	NZ_AP014942.1	1205738-1205771	2	0.941
NZ_AP014942_6	6.1\|838831\|34\|NZ_AP014942\|CRISPRCasFinder	838831-838864	34	NZ_AP014942.1	2619715-2619748	2	0.941
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	144840-144876	2	0.946
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	790234-790270	2	0.946
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	838868-838904	2	0.946
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	903113-903149	2	0.946
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	1613679-1613715	2	0.946
NZ_AP014942_7	7.1\|1121507\|37\|NZ_AP014942\|CRT	1121507-1121543	37	NZ_AP014942.1	1951668-1951704	2	0.946
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	839138-839174	2	0.946
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	839194-839230	2	0.946
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	839250-839286	2	0.946
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	1121675-1121711	2	0.946
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	1205811-1205847	2	0.946
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	1205867-1205903	2	0.946
NZ_AP014942_7	7.2\|1121563\|37\|NZ_AP014942\|CRT	1121563-1121599	37	NZ_AP014942.1	2461887-2461923	2	0.946
NZ_AP014942_7	7.3\|1121619\|37\|NZ_AP014942\|CRT	1121619-1121655	37	NZ_AP014942.1	1734069-1734105	2	0.946

1. spacer 1.1|144880|34|NZ_AP014942|CRISPRCasFinder matches to position: 1429100-1429133, mismatch: 0, identity: 1.0

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
**********************************

2. spacer 5.1|795692|33|NZ_AP014942|CRISPRCasFinder matches to position: 1942283-1942315, mismatch: 0, identity: 1.0

cttttcgaaattctctgtgttggggcccacacc	CRISPR spacer
cttttcgaaattctctgtgttggggcccacacc	Protospacer
*********************************

3. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 2297317-2297353, mismatch: 0, identity: 1.0

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcaaaaagaaattctacagacaatgcaagttg	Protospacer
*************************************

4. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 348042-348078, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

5. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 802880-802916, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

6. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 1019123-1019159, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

7. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 1474141-1474177, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

8. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 1613737-1613773, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

9. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 1940917-1940953, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

10. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 2331631-2331667, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

11. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 749138-749174, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

12. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 1429080-1429116, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

13. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 1474197-1474233, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

14. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 1942318-1942354, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

15. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 1942377-1942413, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

16. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 2331687-2331723, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

17. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 2734216-2734252, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

18. spacer 1.1|144880|34|NZ_AP014942|CRISPRCasFinder matches to position: 1205738-1205771, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaagttggattcccaat	Protospacer
********************.*************

19. spacer 1.1|144880|34|NZ_AP014942|CRISPRCasFinder matches to position: 2619715-2619748, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaaattggattgccaat	Protospacer
**************************** *****

20. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 839190-839224, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcttacaataatgtgcaagttggcg	Protospacer
************ **********************

21. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 839246-839280, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcttacaataatgtgcaagttggcg	Protospacer
************ **********************

22. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 1205817-1205851, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcttacaataatgtgcaagttggcg	Protospacer
************ **********************

23. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 2297369-2297403, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cgaaaagtcagcatacaataatgtgcaagttggcg	Protospacer
**.********************************

24. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 2461883-2461917, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcttacaataatgtgcaagttggcg	Protospacer
************ **********************

25. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 2734100-2734134, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcctacaataatgtgcaagttggcg	Protospacer
************ **********************

26. spacer 6.1|838831|34|NZ_AP014942|CRISPRCasFinder matches to position: 1429100-1429133, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

27. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 1340100-1340136, mismatch: 1, identity: 0.973

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacagacaatgcaagttg	Protospacer
*******.*****************************

28. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 2487210-2487246, mismatch: 1, identity: 0.973

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcaaaaagaaattctacagacaatgtaagttg	Protospacer
******************************.******

29. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 2619675-2619711, mismatch: 1, identity: 0.973

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacagacaatgcaagttg	Protospacer
*******.*****************************

30. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 1429138-1429174, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agatgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
** **********************************

31. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 2297373-2297409, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcatacaataatgtgcaagtt	Protospacer
****************** ******************

32. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 2569085-2569121, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaaatcagcttacaataatgtgcaagtt	Protospacer
************.************************

33. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 795727-795763, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggatttccaatttctacagacaatgcaagtt	Protospacer
***********.*************************

34. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 1205755-1205791, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaagttggattcccaatttctacagacaatgcaagtt	Protospacer
***.*********************************

35. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 2569029-2569065, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgtaagtt	Protospacer
*******************************.*****

36. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 2619732-2619768, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattgccaatttctacagacaatgcaagtt	Protospacer
*********** *************************

37. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 2734160-2734196, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccgatttctacagacaatgcaagtt	Protospacer
**************.**********************

38. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 758700-758734, mismatch: 2, identity: 0.943

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagctaacaataatgtgcaagttggcg	Protospacer
************  *********************

39. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 1117601-1117635, mismatch: 2, identity: 0.943

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cgaaaagtcagcatacaaaaatgtgcaagttggcg	Protospacer
**.*************** ****************

40. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 1474147-1474181, mismatch: 2, identity: 0.943

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cgaaaagtcagcttacaataatgtgcaagttggcg	Protospacer
**.********* **********************

41. spacer 2.1|268154|35|NZ_AP014942|CRISPRCasFinder matches to position: 2331637-2331671, mismatch: 2, identity: 0.943

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cgaaaagtcagcttacaataatgtgcaagttggcg	Protospacer
**.********* **********************

42. spacer 6.1|838831|34|NZ_AP014942|CRISPRCasFinder matches to position: 1205738-1205771, mismatch: 2, identity: 0.941

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaacttctctttgttggggcccat	Protospacer
****.********.********************

43. spacer 6.1|838831|34|NZ_AP014942|CRISPRCasFinder matches to position: 2619715-2619748, mismatch: 2, identity: 0.941

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attggcaatccaatttctctttgttggggcccat	Protospacer
****. ****************************

44. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 144840-144876, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

45. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 790234-790270, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaaacaatgcaagttg	Protospacer
*******.***************.*************

46. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 838868-838904, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

47. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 903113-903149, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

48. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 1613679-1613715, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

49. spacer 7.1|1121507|37|NZ_AP014942|CRT matches to position: 1951668-1951704, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaggaaattctacagacaatgcaagttg	Protospacer
*******.***.*************************

50. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 839138-839174, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

51. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 839194-839230, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

52. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 839250-839286, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

53. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 1121675-1121711, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

54. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 1205811-1205847, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

55. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 1205867-1205903, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

56. spacer 7.2|1121563|37|NZ_AP014942|CRT matches to position: 2461887-2461923, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

57. spacer 7.3|1121619|37|NZ_AP014942|CRT matches to position: 1734069-1734105, mismatch: 2, identity: 0.946

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggacccccaatttctacagacaatgcaagtt	Protospacer
*********..**************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP014942_8	8.1\|1734127\|27\|NZ_AP014942\|CRISPRCasFinder	1734127-1734153	27	KM359505	Prochlorococcus phage P-TIM68, complete genome	102710-102736	5	0.815

1. spacer 8.1|1734127|27|NZ_AP014942|CRISPRCasFinder matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 5, identity: 0.815

gaatttcgaaaagaaattctacagacc	CRISPR spacer
ctatttccaaaagaaattatacagatc	Protospacer
  ***** ********** ******.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

727314 : 735134

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|727314_728370_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|728369_729056_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|729030_729504_-	DoxX family protein	NA	NA	NA	NA
WP_001093556.1\|729845_730286_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637687.1\|730565_731150_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|731248_731962_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|731965_732385_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|732386_733055_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604515.1\|733405_733999_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
WP_001217794.1\|733982_735134_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	3.5e-23	36.1

DBSCAN-SWA_2

747105 : 761835

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663025.1\|747105_748164_+	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	1.5e-20	27.3
WP_000197275.1\|748458_749001_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429006.1\|749680_750598_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_031797439.1\|750687_750789_+	hypothetical protein	NA	NA	NA	NA
WP_060829053.1\|750866_752372_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.5e-58	32.2
WP_000930014.1\|752712_753213_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_042727549.1\|753232_754099_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|754899_755298_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|755260_757366_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|757483_758455_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|758968_759124_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|759162_760134_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|760120_761077_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616842.1\|761073_761835_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_3

840537 : 860911

Staphylococcus_phage(81.82%)

integrase,coat,terminase

attL 843074:843090|attR 858173:858189

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571218.1\|840537_841563_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-27	36.8
WP_000520233.1\|841555_842251_+	ABC transporter permease	NA	NA	NA	NA
WP_000732326.1\|842268_843090_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
843074:843090	attL	NA	NA	NA	NA
WP_000264181.1\|843232_844453_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	4.6e-98	47.3
WP_042727546.1\|844540_845269_-	staphylococcal enterotoxin type K	A0EX09	Staphylococcus_phage	1.6e-21	31.8
WP_001033317.1\|845292_846021_-	staphylococcal enterotoxin type Q	A0EX09	Staphylococcus_phage	7.9e-29	35.4
WP_000142630.1\|846195_846930_-	helix-turn-helix transcriptional regulator	Q4ZE79	Staphylococcus_phage	8.5e-132	98.4
WP_001063624.1\|847079_847292_+	helix-turn-helix transcriptional regulator	Q4ZE78	Staphylococcus_phage	3.4e-33	98.6
WP_001138298.1\|847292_847565_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	3.4e-46	100.0
WP_012990927.1\|847576_847723_+	hypothetical protein	NA	NA	NA	NA
WP_001058492.1\|847715_847925_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	7.7e-30	95.7
WP_001103944.1\|847927_848248_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	6.5e-20	58.2
WP_042727545.1\|848314_849184_+	primase C-terminal domain-containing protein	A0A1W6JQL5	Staphylococcus_phage	3.0e-160	95.5
WP_042727544.1\|849200_850658_+	virulence-associated protein E	A0A1W6JQD6	Staphylococcus_phage	4.6e-278	96.1
WP_042727543.1\|850959_851322_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	1.2e-62	93.3
WP_042727542.1\|851323_851608_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.4e-45	92.6
WP_042727541.1\|851604_852246_+	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	7.7e-113	94.4
WP_042727540.1\|852819_853161_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	5.4e-57	97.3
WP_000846284.1\|853172_853751_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	4.8e-29	38.9
WP_000448775.1\|853768_853987_+	hypothetical protein	NA	NA	NA	NA
WP_000771380.1\|854037_854565_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	2.1e-87	95.4
WP_001656917.1\|854696_854909_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	5.4e-31	97.1
WP_001293071.1\|854905_855475_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	4.6e-101	98.4
WP_000801979.1\|855751_856720_+	Abi family protein	A0A0H4U080	Erysipelothrix_phage	5.9e-24	27.3
WP_001035618.1\|856954_857509_-	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	4.8e-71	76.1
WP_000752917.1\|858542_858737_+	CsbD family protein	NA	NA	NA	NA
858173:858189	attR	NA	NA	NA	NA
WP_001183858.1\|858970_859822_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_000168845.1\|860149_860911_+	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3

DBSCAN-SWA_4

1020636 : 1029109

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1020636_1021119_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010407.1\|1021105_1022230_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1022233_1022938_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1022937_1023201_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666806.1\|1023202_1023874_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_042727722.1\|1023866_1026056_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-141	39.8
WP_000483720.1\|1026034_1027519_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
WP_042727723.1\|1027511_1028540_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_000238669.1\|1028542_1029109_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_5

1287143 : 1303350

Staphylococcus_phage(54.17%)

integrase,head,terminase,portal

attL 1279346:1279363|attR 1307083:1307100

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1279346:1279363	attL	NA	NA	NA	NA
WP_001836882.1\|1287143_1288271_-\|integrase	site-specific integrase	A0A0C5AN64	Paenibacillus_phage	6.2e-33	31.4
WP_001183750.1\|1288323_1289019_-	Ltp family lipoprotein	A0A2H4J5B8	uncultured_Caudovirales_phage	3.6e-07	50.3
WP_000554410.1\|1289030_1289414_-	hypothetical protein	NA	NA	NA	NA
WP_000664917.1\|1289560_1289953_-	helix-turn-helix domain-containing protein	A0A2I6PE55	Staphylococcus_phage	1.6e-28	53.6
WP_001209962.1\|1290120_1290339_+	DUF739 family protein	A0A2I6PE94	Staphylococcus_phage	4.9e-19	62.5
WP_000932238.1\|1290365_1290641_+	hypothetical protein	NA	NA	NA	NA
WP_000392387.1\|1290905_1291076_+	hypothetical protein	Q4ZDZ8	Staphylococcus_virus	2.4e-21	89.3
WP_000800341.1\|1291064_1291271_-	hypothetical protein	A1BTY8	Staphylococcus_virus	3.3e-25	75.0
WP_001157025.1\|1291331_1292015_+	phage repressor protein	A9CR56	Staphylococcus_phage	5.2e-107	85.6
WP_000072840.1\|1292113_1292275_+	DUF1270 family protein	R4IH12	Staphylococcus_phage	1.1e-12	69.8
WP_000786993.1\|1292361_1292679_+	DUF2482 family protein	W5RAK4	Staphylococcus_phage	1.6e-39	80.6
WP_000786634.1\|1292668_1292935_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	3.0e-18	53.6
WP_001004327.1\|1292939_1293476_+	host-nuclease inhibitor Gam family protein	A0A0H3U480	Staphylococcus_phage	1.7e-76	82.5
WP_042727645.1\|1293476_1294256_+	ATP-binding protein	A0A1W6JPW0	Staphylococcus_phage	6.7e-127	87.6
WP_000702007.1\|1294282_1294831_+	hypothetical protein	A7TWM8	Staphylococcus_phage	1.1e-91	92.9
WP_000929466.1\|1294843_1295746_+	DnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	2.9e-49	52.0
WP_000946005.1\|1295746_1296037_+	hypothetical protein	A0A223LIA9	Staphylococcus_phage	7.2e-18	58.1
WP_000714410.1\|1296051_1296216_+	hypothetical protein	A0A0E3T9L7	Staphylococcus_phage	1.1e-18	88.9
WP_000860979.1\|1296215_1296527_+	hypothetical protein	NA	NA	NA	NA
WP_000185176.1\|1296519_1297050_+	nucleotide pyrophosphohydrolase	A0A1P8VVP1	Streptococcus_phage	5.2e-22	38.2
WP_025174970.1\|1297191_1297299_+	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	3.2e-08	87.5
WP_000835355.1\|1297295_1297760_+	hypothetical protein	C9E2P0	Enterococcus_phage	3.2e-20	43.0
WP_000653930.1\|1298036_1298525_+	hypothetical protein	R9TMH4	Paenibacillus_phage	4.3e-07	27.7
WP_000090969.1\|1298677_1299106_+	helix-turn-helix domain-containing protein	A1EAE0	Streptococcus_phage	1.1e-25	45.1
WP_000207537.1\|1299092_1300367_+\|terminase	PBSX family phage terminase large subunit	Q4ZE37	Staphylococcus_virus	1.9e-195	76.4
WP_000158568.1\|1300379_1301828_+\|portal	phage portal protein	Q4ZE36	Staphylococcus_virus	7.4e-196	69.4
WP_042727644.1\|1301817_1303350_+\|head	phage head morphogenesis protein	Q4ZE35	Staphylococcus_virus	1.9e-109	61.6
1307083:1307100	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1585290 : 1593620

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1585290_1586076_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_060829067.1\|1586201_1587092_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001062187.1\|1587101_1588448_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683929.1\|1588561_1589662_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624583.1\|1589664_1590342_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1590472_1591579_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217257.1\|1591802_1593620_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.3

DBSCAN-SWA_7

1661441 : 1670484

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1661441_1661960_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594991.1\|1661981_1664255_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	5.2e-63	28.8
WP_000749795.1\|1664457_1666737_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1667011_1667272_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1667290_1668430_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1\|1668452_1669478_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1\|1669479_1670484_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1795789 : 1859947

Staphylococcus_phage(95.56%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050538.1\|1795789_1802350_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.6e-309	99.0
WP_000836465.1\|1802675_1802987_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001808015.1\|1803008_1805426_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.3
WP_001025061.1\|1805713_1806895_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526539.1\|1807004_1807958_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1807954_1808518_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1808637_1809039_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1809610_1810438_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1810440_1810560_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1810671_1811673_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|1811794_1812259_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_042727556.1\|1812271_1813453_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.5e-226	99.5
WP_000493892.1\|1813463_1814096_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_000077358.1\|1814102_1815146_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-196	98.8
WP_001261668.1\|1815626_1817129_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000221177.1\|1817651_1817966_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_000989122.1\|1817965_1819258_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	9.4e-227	99.3
WP_001032833.1\|1819344_1820199_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1820474_1820699_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1820897_1821368_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1821480_1821924_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1821910_1822354_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168901.1\|1822649_1823285_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1823724_1824438_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1824697_1825000_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1825255_1825621_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623478.1\|1825617_1825971_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.6e-22	100.0
WP_000453314.1\|1826353_1827187_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000366163.1\|1827398_1828307_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933822.1\|1828431_1829625_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109906.1\|1829996_1831589_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_001834463.1\|1831966_1832713_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-142	98.8
WP_000672014.1\|1832717_1833191_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_000718107.1\|1833256_1833514_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778525.1\|1833510_1834512_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.2e-186	97.9
WP_000348374.1\|1834516_1835995_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	8.1e-283	97.4
WP_072433592.1\|1836153_1836609_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	5.7e-78	97.9
WP_001795535.1\|1836911_1837562_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
WP_000070655.1\|1837642_1838638_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	6.2e-77	98.8
WP_000669027.1\|1838713_1839340_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	5.3e-90	93.8
WP_000627537.1\|1839380_1839722_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	3.0e-55	95.6
WP_000414214.1\|1839822_1840395_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.1e-25	96.6
WP_000864143.1\|1840591_1841149_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.7e-77	96.2
WP_000375476.1\|1841521_1841698_-	hypothetical protein	NA	NA	NA	NA
WP_000731418.1\|1843249_1843693_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000745473.1\|1843692_1844136_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000221409.1\|1844674_1847098_+	polysaccharide lyase 8 family protein	NA	NA	NA	NA
WP_001036003.1\|1847221_1847599_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000759947.1\|1847804_1848245_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001836790.1\|1848289_1849903_+	hypothetical protein	NA	NA	NA	NA
WP_000095395.1\|1849917_1850217_+	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_047210362.1\|1850343_1851588_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.2e-125	62.1
WP_060829072.1\|1851580_1853137_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.0e-287	99.2
WP_001791797.1\|1853300_1853435_-	hypothetical protein	NA	NA	NA	NA
WP_001038690.1\|1853499_1854219_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.9e-131	99.6
WP_001038757.1\|1854369_1855086_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	2.4e-131	99.2
WP_011447030.1\|1855187_1855295_+	hypothetical protein	NA	NA	NA	NA
WP_001038706.1\|1855243_1855963_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	5.1e-129	99.2
WP_001038872.1\|1856083_1856803_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
WP_001039444.1\|1856860_1857583_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
WP_001039433.1\|1857707_1858415_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.7e-130	99.6
WP_001092776.1\|1859377_1859947_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	2.6e-51	62.6

DBSCAN-SWA_9

1952272 : 2044271

110

Staphylococcus_phage(90.79%)

integrase,transposase,tail,capsid,tRNA,head,protease,terminase,portal,holin

attL 2000085:2000100|attR 2050110:2050125

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000545370.1\|1952272_1953700_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_000027917.1\|1953712_1955170_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|1955171_1955474_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957020.1\|1955840_1957379_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831695.1\|1957467_1958667_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774565.1\|1958679_1960683_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
WP_000992921.1\|1960686_1962879_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272070.1\|1962875_1963568_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|1963739_1964042_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|1964150_1965446_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827750.1\|1966305_1967472_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434934.1\|1967502_1967829_+	staphostatin A	NA	NA	NA	NA
WP_000669861.1\|1968120_1968294_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|1968274_1968877_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040866.1\|1969147_1969969_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000284433.1\|1969961_1971431_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.5e-108	45.1
WP_000897635.1\|1971614_1972691_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177828.1\|1972710_1973505_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|1973576_1973684_+	hypothetical protein	NA	NA	NA	NA
WP_000323164.1\|1973694_1975257_-	SLC13 family permease	NA	NA	NA	NA
WP_000275706.1\|1975461_1976559_-	pectate lyase	U5PWM6	Bacillus_phage	2.5e-47	34.9
WP_000149686.1\|1976930_1977491_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|1977543_1978473_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001808146.1\|1978614_1979934_+\|transposase	ISL3-like element IS1181 family transposase	NA	NA	NA	NA
WP_001790680.1\|1980188_1980362_-	hypothetical protein	NA	NA	NA	NA
WP_001021216.1\|1980413_1981793_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181322.1\|1981912_1982941_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|1983210_1983612_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|1984184_1984358_-	hypothetical protein	NA	NA	NA	NA
WP_001188074.1\|1984808_1985849_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713070.1\|1985905_1986748_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|1986744_1987302_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|1987361_1987886_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|1988006_1988570_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221651.1\|1988635_1989376_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|1989375_1990248_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645725.1\|1990244_1990925_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991303.1\|1990925_1991822_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|1991818_1992199_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|1992457_1992634_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|1992876_1992975_-	hypothetical protein	NA	NA	NA	NA
WP_001068523.1\|1993174_1994461_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_031864371.1\|1995040_1997104_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000669789.1\|1998061_1998241_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001791826.1\|1998551_1998812_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702262.1\|1998864_1999215_-	complement inhibitor SCIN-A	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
2000085:2000100	attL	NA	NA	NA	NA
WP_000920041.1\|2000711_2001203_-	staphylokinase	A7TWR8	Staphylococcus_phage	8.0e-86	100.0
WP_000861038.1\|2001393_2002149_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000611512.1\|2002160_2002415_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_001791821.1\|2002466_2002574_+	hypothetical protein	NA	NA	NA	NA
WP_072353918.1\|2002626_2002803_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	5.5e-21	94.8
WP_000340977.1\|2002945_2003320_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001262620.1\|2003375_2003663_-	hypothetical protein	C5I682	Staphylococcus_phage	9.9e-44	100.0
WP_001000058.1\|2003708_2003861_-	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
WP_042727565.1\|2003853_2007636_-	phage minor structural protein	R9QT86	Staphylococcus_phage	0.0e+00	100.0
WP_001154317.1\|2007651_2009142_-\|tail	phage tail family protein	R9QST9	Staphylococcus_phage	3.1e-298	100.0
WP_042727566.1\|2009141_2013791_-\|tail	phage tail tape measure protein	R9QSQ8	Staphylococcus_phage	0.0e+00	100.0
WP_000570353.1\|2013846_2013969_-	hypothetical protein	D2JLF6	Staphylococcus_phage	6.9e-15	100.0
WP_000442601.1\|2014028_2014475_-	hypothetical protein	D2JLF5	Staphylococcus_phage	5.4e-73	100.0
WP_000570652.1\|2014539_2015493_-	Ig-like domain-containing protein	A7TWD0	Staphylococcus_phage	6.2e-175	100.0
WP_000611452.1\|2015493_2015874_-	hypothetical protein	D2JLF3	Staphylococcus_phage	5.8e-68	100.0
WP_000501244.1\|2015870_2016248_-	HK97 gp10 family phage protein	D2JLF2	Staphylococcus_phage	1.1e-61	100.0
WP_000975314.1\|2016247_2016583_-\|head,tail	head-tail adaptor protein	A7TWC7	Staphylococcus_phage	1.1e-59	100.0
WP_001177483.1\|2016569_2016902_-\|head,tail	phage head-tail connector protein	D2JLF0	Staphylococcus_phage	2.1e-58	100.0
WP_001252099.1\|2016910_2017069_-	hypothetical protein	D2JLE9	Staphylococcus_phage	3.2e-20	100.0
WP_000849950.1\|2017104_2018352_-\|capsid	phage major capsid protein	A7TWC4	Staphylococcus_phage	5.0e-209	100.0
WP_000032525.1\|2018439_2019024_-\|head,protease	HK97 family phage prohead protease	D2JLE7	Staphylococcus_phage	9.8e-107	100.0
WP_000511068.1\|2019016_2020267_-\|portal	phage portal protein	R9QSV8	Staphylococcus_phage	1.7e-236	100.0
WP_001836552.1\|2020272_2020473_-	hypothetical protein	R9QT78	Staphylococcus_phage	7.6e-27	100.0
WP_000133306.1\|2020486_2022181_-\|terminase	terminase	A0A1V0E5G5	Staphylococcus_phage	0.0e+00	100.0
WP_000919026.1\|2022183_2022651_-\|terminase	phage terminase small subunit P27 family	D2JLE3	Staphylococcus_phage	1.1e-81	100.0
WP_000817289.1\|2022780_2023125_-	HNH endonuclease	D2JLE2	Staphylococcus_phage	4.2e-65	100.0
WP_000406187.1\|2023140_2023593_-	nucleoside triphosphate pyrophosphohydrolase family protein	R9QTP3	Staphylococcus_phage	1.8e-79	100.0
WP_000282753.1\|2023707_2024169_-	hypothetical protein	R9QT84	Staphylococcus_phage	8.7e-74	100.0
WP_000265041.1\|2024191_2024392_-	DUF1514 family protein	R9QT57	Staphylococcus_phage	1.1e-28	100.0
WP_001005262.1\|2024391_2025042_-	hypothetical protein	D2JLD8	Staphylococcus_phage	8.9e-117	100.0
WP_000595267.1\|2025200_2025350_-	hypothetical protein	R9QSU6	Staphylococcus_phage	1.8e-17	100.0
WP_000195810.1\|2025346_2025553_-	DUF1381 domain-containing protein	S4V684	Staphylococcus_phage	7.6e-30	100.0
WP_000185669.1\|2025589_2026126_-	dUTP diphosphatase	R4IG63	Staphylococcus_phage	9.4e-96	100.0
WP_001065083.1\|2026118_2026367_-	DUF1024 family protein	A0A2K9VBU0	Staphylococcus_phage	3.1e-38	100.0
WP_001105621.1\|2026359_2026644_-	hypothetical protein	E9LT36	Staphylococcus_phage	2.7e-46	100.0
WP_000982708.1\|2026640_2027090_-	hypothetical protein	A0A2I6PDH2	Staphylococcus_phage	9.3e-81	100.0
WP_000693615.1\|2027277_2027664_-	hypothetical protein	I1W655	Staphylococcus_phage	4.1e-69	100.0
WP_000131377.1\|2027677_2027920_-	hypothetical protein	R9QT89	Staphylococcus_phage	3.0e-41	100.0
WP_000101270.1\|2027923_2028292_-	hypothetical protein	A0A0E3XD52	Staphylococcus_phage	6.7e-53	100.0
WP_000401964.1\|2028304_2028709_-	RusA family crossover junction endodeoxyribonuclease	A0A0E3XBN4	Staphylococcus_phage	1.4e-72	100.0
WP_000338528.1\|2028717_2028936_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
WP_000148329.1\|2028942_2029836_-	DnaD domain-containing protein	A0A0E3TAG7	Staphylococcus_phage	1.1e-141	100.0
WP_000934769.1\|2029865_2030336_-	single-stranded DNA-binding protein	A0A0E3T9H6	Staphylococcus_phage	5.7e-81	100.0
WP_071621397.1\|2030336_2030954_-	MBL fold metallo-hydrolase	S4SWA4	Staphylococcus_phage	9.1e-87	100.0
WP_000138475.1\|2031034_2031955_-	recombinase RecT	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
WP_001813910.1\|2031956_2033912_-	AAA family ATPase	R9QT82	Staphylococcus_phage	0.0e+00	100.0
WP_042727568.1\|2033908_2034172_-	hypothetical protein	R9QT48	Staphylococcus_phage	7.7e-43	100.0
WP_000291488.1\|2034180_2034441_-	DUF1108 family protein	A0A2I6PDH1	Staphylococcus_phage	2.6e-43	100.0
WP_000066020.1\|2034533_2034695_-	DUF1270 domain-containing protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
WP_001798161.1\|2034691_2035012_-	DUF771 domain-containing protein	R9QT52	Staphylococcus_phage	1.5e-56	100.0
WP_000801108.1\|2035070_2035298_+	hypothetical protein	A7TWL9	Staphylococcus_phage	1.7e-38	100.0
WP_000389906.1\|2035299_2035491_-	hypothetical protein	A7TWL8	Staphylococcus_phage	2.8e-26	100.0
WP_000768245.1\|2035540_2035897_+	DUF2513 domain-containing protein	A0A1P8L6H1	Staphylococcus_phage	6.1e-59	100.0
WP_001148859.1\|2035891_2036086_-	hypothetical protein	A0A1P8L6G6	Staphylococcus_phage	4.3e-19	100.0
WP_001148565.1\|2036101_2036890_-	phage antirepressor KilAC domain-containing protein	R9QSV3	Staphylococcus_phage	1.2e-144	100.0
WP_000639922.1\|2036905_2037148_-	DUF739 family protein	R9QSU1	Staphylococcus_phage	9.5e-40	100.0
WP_001083967.1\|2037311_2038028_+	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	9.2e-131	100.0
WP_000804508.1\|2038039_2038897_+	restriction endonuclease	R9QTP0	Staphylococcus_phage	1.2e-161	100.0
WP_000705243.1\|2038941_2039124_+	hypothetical protein	R9QT81	Staphylococcus_phage	5.3e-27	100.0
WP_001013104.1\|2039159_2039306_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.1e-14	89.6
WP_000191459.1\|2039302_2039917_-	hypothetical protein	A7TW88	Staphylococcus_phage	7.9e-107	100.0
WP_000857176.1\|2040024_2041062_+\|integrase	site-specific integrase	A7TWL3	Staphylococcus_phage	3.4e-179	100.0
WP_000595401.1\|2042180_2043197_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	2.3e-26	29.3
WP_000791404.1\|2043218_2044271_-	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.5e-36	34.6
2050110:2050125	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_AP014943

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

10055 : 18966

Staphylococcus_phage(57.14%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000277738.1\|10055_11702_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.0e-289	98.4
WP_000378396.1\|12064_14245_-	cadmium-translocating P-type ATPase CadA	E4ZFI9	Streptococcus_phage	9.3e-251	63.7
WP_000159128.1\|14237_14603_-	winged helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	8.5e-24	47.8
WP_000361064.1\|14840_15218_-	hypothetical protein	NA	NA	NA	NA
WP_001105942.1\|15312_15987_+\|transposase	IS6-like element ISSau6 family transposase	A0A0N9RU54	Staphylococcus_phage	1.3e-113	88.4
WP_001035802.1\|16021_16234_-	hypothetical protein	NA	NA	NA	NA
WP_000633163.1\|16553_16889_+	recombinase family protein	NA	NA	NA	NA
WP_000120605.1\|16949_17264_+	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4PQT4	Staphylococcus_phage	4.7e-39	73.1
WP_001834181.1\|17260_18553_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	3.0e-188	81.4
WP_000358995.1\|18570_18966_+	thioredoxin-dependent arsenate reductase	A0A2H4PQT9	Staphylococcus_phage	8.5e-62	86.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP014942

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_AP014943

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection