CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014240	Selenomonas sp. oral taxon 136 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP014239	Selenomonas sp. oral taxon 136 strain F0591, complete genome	4 crisprs	DEDDh,cas2,csm6,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,csx20,csx10gr5,csx19,csa3,WYL	0	2	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014239_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014239_1

1018343-1018738

TypeIII

Consensus_repeat	Method
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	CRISPRCasFinder
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	CRT
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	PILER-CR

5 spacers

cas2,csm6,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10

The CRISPR arrays of NZ_CP014239_1

>merge|NZ_CP014239|1|1018343-1018738|CRISPRCasFinder,CRT,PILER-CR
GGTTCCGGCCCCTTACGGGGATATGGTTTTGAAATGTCAAGAAGGTGCATGGAACCATTATGGTATGCCTAGTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAATAGTGTGCGAGTGTTGCATAGGGCGTCGCGCCTCATGGCCGTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAATTCCCTTAACTGGAAGCGTTGGTGCTCTGTTTTTGGTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAATATACTGTTTCCCTTATCATTTCGGCAATCTGCCCTATTGTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAATTGTAAGCGCGGTGAAGGCGTTCAGGACAGCACGAAAAGAGTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT

>NZ_CP014239|1|1|1018343-1018738|CRISPRCasFinder
GGTTCCGGCCCCTTACGGGGATATGGTTTTGAAAT	GTCAAGAAGGTGCATGGAACCATTATGGTATGCCTA
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	AGTGTGCGAGTGTTGCATAGGGCGTCGCGCCTCATGGCC
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	TCCCTTAACTGGAAGCGTTGGTGCTCTGTTTTTG
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	ATACTGTTTCCCTTATCATTTCGGCAATCTGCCCTATT
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	TGTAAGCGCGGTGAAGGCGTTCAGGACAGCACGAAAAGA
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT

>NZ_CP014239|1|1|1018343-1018738|CRT
GGTTCCGGCCCCTTACGGGGATATGGTTTTGAAAT	GTCAAGAAGGTGCATGGAACCATTATGGTATGCCTA
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	AGTGTGCGAGTGTTGCATAGGGCGTCGCGCCTCATGGCC
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	TCCCTTAACTGGAAGCGTTGGTGCTCTGTTTTTG
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	ATACTGTTTCCCTTATCATTTCGGCAATCTGCCCTATT
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	TGTAAGCGCGGTGAAGGCGTTCAGGACAGCACGAAAAGA
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT

>NZ_CP014239|1|1|1018414-1018738|PILER-CR
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	AGTGTGCGAGTGTTGCATAGGGCGTCGCGCCTCATGGCC
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	TCCCTTAACTGGAAGCGTTGGTGCTCTGTTTTTG
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	ATACTGTTTCCCTTATCATTTCGGCAATCTGCCCTATT
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT	TGTAAGCGCGGTGAAGGCGTTCAGGACAGCACGAAAAGA
GTTTCCGTCCCCTTGCGGGGATGTGGTTTTAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014239.1\|WP_009753315.1\|1009883_1010147_-\|Txe/YoeB-family-addiction-module-toxin	unknown	unknown	gnl\|CDD\|284238
NZ_CP014239.1\|WP_061945234.1\|1011196_1012303_-\|aminofutalosine-synthase-MqnE	unknown	unknown	gnl\|CDD\|213851
NZ_CP014239.1\|WP_061945236.1\|1012441_1013209_-\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|224790
NZ_CP014239.1\|WP_061945250.1\|1021958_1023191_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NZ_CP014239.1\|WP_050342403.1\|1010146_1010413_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NZ_CP014239.1\|WP_061945256.1\|1024931_1025357_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NZ_CP014239.1\|WP_083501155.1\|1028490_1028676_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_CP014239.1\|WP_083501203.1\|1024194_1024929_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP014239.1\|WP_061945226.1\|1007815_1008370_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014239.1\|WP_061945239.1\|1014010_1016038_+\|oligopeptide-transporter,-OPT-family	unknown	unknown	gnl\|CDD\|224216
NZ_CP014239.1\|WP_061945258.1\|1025349_1027770_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP014239.1\|WP_061945248.1\|1021219_1021975_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	COG5551_cas6_CAS-III	gnl\|CDD\|227838
NZ_CP014239.1\|WP_061945232.1\|1010488_1011124_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376839
NZ_CP014239.1\|WP_061945247.1\|1019861_1021214_-\|hypothetical-protein	csm6	pfam09659_csm6_CAS-III-A	gnl\|CDD\|312974
NZ_CP014239.1\|WP_061945243.1\|1016839_1018108_-\|pectate-lyase	unknown	unknown	gnl\|CDD\|226384
NZ_CP014239.1\|WP_061945245.1\|1019092_1019410_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP014239.1\|WP_061945260.1\|1028068_1028473_-\|antitoxin-HicB	unknown	unknown	gnl\|CDD\|374224
NZ_CP014239.1\|WP_061945241.1\|1016144_1016564_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|334450
NZ_CP014239.1\|WP_061945252.1\|1023187_1024198_-\|hypothetical-protein	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|380071
NZ_CP014239.1\|WP_061945228.1\|1008350_1008680_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP014239.1\|WP_009753315.1\|1009883_1010147_-\|Txe/YoeB-family-addiction-module-toxin	gnl\|CDD\|284238	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system. YoeB_toxin is a family of bacterial toxins that forms one component of the type II toxin-antitoxin system in E. coli whose antitoxin is represented by YefM, found in pfam02604. The plasmid encoded Axe-Txe proteins in Enterococcus faecium act as an antitoxin-toxin pair. When the plasmid is lost, the antitoxin is degraded relatively quickly by host enzymes. This allows the toxin to interact with its intracellular target, thus killing the cell or impeding cell growth. These toxins are highly potent protein synthesis inhibitors, specifically blocking the initiation of translation. In the case of YoeB, it binds to the 50 S ribosomal subunit in 70 S ribosomes and interacts with the A site leading to mRNA cleavage at this site. As a result, the 3'-end portion of the mRNA is released from ribosomes, and translation initiation is effectively inhibited.	1.00147e-32
NZ_CP014239.1\|WP_061945234.1\|1011196_1012303_-\|aminofutalosine-synthase-MqnE	gnl\|CDD\|213851	TIGR03700, mena_SCO4494, putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family. Members of this protein family appear to be involved in menaquinone biosynthesis by an alternate pathway via futalosine, based on close phylogenetic correlation with known markers of the futalosine pathway, gene clustering in many organisms, and paralogy with the SCO4550 protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	7.9993e-163
NZ_CP014239.1\|WP_061945236.1\|1012441_1013209_-\|cyclase-family-protein	gnl\|CDD\|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	1.21209e-46
NZ_CP014239.1\|WP_061945250.1\|1021958_1023191_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	1.23858e-13
NZ_CP014239.1\|WP_050342403.1\|1010146_1010413_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	9.78952e-11
NZ_CP014239.1\|WP_061945256.1\|1024931_1025357_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	1.13579e-22
NZ_CP014239.1\|WP_083501155.1\|1028490_1028676_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	5.70257e-18
NZ_CP014239.1\|WP_083501203.1\|1024194_1024929_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	2.25548e-72
NZ_CP014239.1\|WP_061945239.1\|1014010_1016038_+\|oligopeptide-transporter,-OPT-family	gnl\|CDD\|224216	COG1297, COG1297, Predicted membrane protein [Function unknown].	0
NZ_CP014239.1\|WP_061945258.1\|1025349_1027770_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	6.85904e-175
NZ_CP014239.1\|WP_061945248.1\|1021219_1021975_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.64566e-16
NZ_CP014239.1\|WP_061945245.1\|1019092_1019410_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.46623e-24
NZ_CP014239.1\|WP_061945232.1\|1010488_1011124_-\|hypothetical-protein	gnl\|CDD\|376839	pfam02589, LUD_dom, LUD domain. This entry represents a domain found in lactate utilization proteins B (LutB) and C (LutC), as well as several uncharacterized proteins. LutB and LutC are encoded by th conserved LutABC operon in bacteria. They are involved in lactate utilization and is implicated in the oxidative conversion of L-lactate into pyruvate.	3.01183e-22
NZ_CP014239.1\|WP_061945243.1\|1016839_1018108_-\|pectate-lyase	gnl\|CDD\|226384	COG3866, PelB, Pectate lyase [Carbohydrate transport and metabolism].	1.18908e-61
NZ_CP014239.1\|WP_061945247.1\|1019861_1021214_-\|hypothetical-protein	gnl\|CDD\|312974	pfam09659, Cas_Csm6, CRISPR-associated protein (Cas_Csm6). Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	2.42861e-44
NZ_CP014239.1\|WP_061945260.1\|1028068_1028473_-\|antitoxin-HicB	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	4.79114e-11
NZ_CP014239.1\|WP_061945241.1\|1016144_1016564_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	5.87502e-09
NZ_CP014239.1\|WP_061945252.1\|1023187_1024198_-\|hypothetical-protein	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	2.41965e-20

>NZ_CP014239.1|WP_061945243.1|1016839_1018108_-|pectate-lyase
MKKKLLLIACIGALAAIFILPFVQSSMGKTDFIREVLAKNDGFAAEGSGTTGGAAAVEDNIFRVTNRQEFIAALGNRKNTEPRLLMIYGTIDFDTDADGKHLTKEDYMAEGYDFQQYLESHAPHSNAPKSRKEEQEEKRKQSQKNQEKNIMVHVPANTSIIGIEHAKLKGVDLVLDADNVIIRNIMFESPYDYFPSWDPNDGPDGSWNSQYDSVTIRGGTHIWIDHCHFEDGQQPTETYFHREYEHRDGLVDIVNQADDITMSYNVFERHNKAILIGNSDAKTADDGKLNVTLHHNYFHNLVQRAPRVRFGKVHVYNNYYQTDDENGAYRYAYSLGVGKNSKIYAENNVADIDGRTYQDFVKVFGGTEFTAVNTIFNGEKIDTFNEHLSPVMWTPERFMKIDDVNEVKSKVLQQAGVLKNED
>NZ_CP014239.1|WP_061945241.1|1016144_1016564_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MNLRDEFERIMREQREIALATTTDGLPHVRIVNFYYTPEEHCVYFATFKDNEKVVEIAANPNIAFTTVPHNGTNEHVRASGRAVKSARTVYDLAALFAAKIPRYQETIDAVGDDLILYEISLDTAVVTIDMEHIERIRL
>NZ_CP014239.1|WP_061945239.1|1014010_1016038_+|oligopeptide-transporter,-OPT-family
MKHSENEFMQHELRLPELTMRGMILGAILTIIFTASNVYLGLKVGLTFSSAIPAAVISMAVLKMAKDANILENNMVQTQASAAGTLSAIIFIIPGMLMIGYWQDFEFWQTLVVSACGGCLGVLFTIPLRRAMVVHSDLAYPEGVAAAEILKVGSHDDSREQHGSGLKEILSGSAIAGVIAFLTNGLQVLGGSLSAWFHVGRGMTQLPLGYSSALVGAGYLIGITSGLAMLIGIAIAWAGFVPYFTITGALPDGMTLQKFAGTVYQQKVRLIGAGAMGVAAIWTLLCLARPVIDGVKESIAGARADSAERGLHRMDIDMTMKSVGLVFAVTVIGLLVIFYAFVSPEQIPGSQKVIFTLVGVGVAVLMGFFVAAACAYMAGLVGTSSSPISGIGILGIIVASLVMYSLCSMFGIFALPGGEKFATATAIFTTSIILAIACISNDNMQDLKTGYLVGATPWRQQVALLIGCVIGALVIAPVLNLLYEAYGFSGALPRAGMDPAQALAAPQAVLMTTIAQGIFSQKLAWEYIYIGIGVGIVLVLIDLFLRRSTKNLAMPPLAVGMGIYLPPVIQTPLVVGAILGYFLNRRLRQTHGEDEERVGLRRGTLFASGLIVGESIIGVLLAGIIVVSVSNGGSESPLAVVGADFAGTAEMLGLLVFLGVLAIFGKVVLSGKKET
>NZ_CP014239.1|WP_061945236.1|1012441_1013209_-|cyclase-family-protein
MGYQLWNALEELKSDAYEWVDLTHPLNNDSPCWAGIPEGSVELSKTCFDWGNPMLDCLIQTFKFPGQFGTHIDFPGHFVRNLPLAEDFGARHMLYPLCVIDVTEQVARDVHYAVTVEDIKAYEAKYGAIPDGAFVALYTGWSRHWPDMDAISGIAADGSENFPSWSMDALKYIYETRNAAANGHETLDTDASTEAAKAGDLACERYVLGKGKLQVEVLTNLDRVAPAGALLFLGWPNIEGATGLPVRALAITPKK
>NZ_CP014239.1|WP_061945234.1|1011196_1012303_-|aminofutalosine-synthase-MqnE
MCLGDDELQSKYLDIEKKAERGERLTYEDGVALFASHDIAWLGALADHVRAEKCGDIVYYNVNCHVNLTNICMAHCKFCAFGRDAEDAGAYEMSASEAVAHVAEAMRDPHLAGLHVVSGLHPTWTFDDYLLRLRALHEAFPSLYLKGFTGVEITHFAHTSGLSVREVLLRLREAGLQSIAGGGAEILSDRVRGELCPNKATADEWLATHRTAHELGIKTNASMLYGHIEMLEERVAHMMRLRDLQDETGGFQTFIPFPFLPSHTELGRTVRQTSMWDDLRTIAIARLLLDNFRNIKAYWVMLTVPVAQVALGFGANDIDGTVHKETILHDAGAKSPRALSEDHIIRIIREIGRTPAACDSNFNIIETY
>NZ_CP014239.1|WP_061945232.1|1010488_1011124_-|hypothetical-protein
MSDTTDEERIVRTMEAFRKNRYDVSRFAERTAAADYLAREIRGKRVGFGDSETLRALSLYERLSEHNEVVDPPRAGHVGGIEAFLAAGREALMTDIFVLSANAITEEGQILNMDGAGNRVAGSLFGHEKTYFVVGINKLVPNIEAGIDRIHRIAAPRNAQRKGKKTPCAAAGDRCYDCAALERICNALTIHYKKMSYRPMELVLIEEKLGL
>NZ_CP014239.1|WP_050342403.1|1010146_1010413_-|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MAQTMVNFRMDAELKQRMEETCHKMGLTLTAAFTMFAAKVTQDRRIPFEVTAEPDPFYSEENMARLRAAIADVKAGRNLTEHELIEAD
>NZ_CP014239.1|WP_009753315.1|1009883_1010147_-|Txe/YoeB-family-addiction-module-toxin
MDKIWQDAAWADYLYWQMQDKKTLKKINRLLQSIDRSGYDCQGQPEPLKGDLSGFWSVRIDAKNRIVFRIVDNRMEIAQCGSHYRDK
>NZ_CP014239.1|WP_061945228.1|1008350_1008680_-|hypothetical-protein
MMKADLRFLQYTPDFISGTMSLREPQKISLEVLANILQVVPPEKGIDLKGALQKVHGLYPTCTDFEREFLSLLPALYGATWLRGYAKHRHDVPAGHCRKDLQADDAALS
>NZ_CP014239.1|WP_061945226.1|1007815_1008370_-|hypothetical-protein
MMQHFHKTEEMFSYDIVKVNDFNMPQELFGSSELDLFSPDAKADGIRSVVFTGIEKGVFDRAKFDSIPELTFARLCEQDVKVLKWLRPAPSDFDLKYGRGHNYEPDFVVETADRCYLVEIKGEDKLNDTGVLAKKEVGIRYCQTATAVCRELHYKPWDYVFIPSKQVQPTSSMEYLCGQFVCHV
>NZ_CP014239.1|WP_061945245.1|1019092_1019410_-|CRISPR-associated-endonuclease-Cas2
MEYDYDESEFCAADERRCIVLIIYDITDNKRRTKMVKCLERYGVRVQKSAFEAFLTARKYDDLIARTTRLIDPRTDSLRIYLLANHTSVRSWGVGDRHVEDVIIF
>NZ_CP014239.1|WP_061945247.1|1019861_1021214_-|hypothetical-protein
MKRILFSPLGDTDPIRDCHDGACLHILRHYQPERVVLFYTKDMENKERRDHRYTRAIHKLSPNCAIEEIFSGIVAAYLYEEFSKILPEAVQSVRDRYPEHEILINLSSGTPQMKTVLAMLAADTERCRGIQVPSHSGKSNRKNRPASDDVDVDILLELNEDDEEGAKNRCEEPPLSVFRYHAEKNRIISLIRAYEYNAALTLARSSSLVPADAKLLLKHAAARTDLLPDKARKILAEYDGQKLFLFTGEEELLMEYFLIMQIDQENDHLSNFMLRISPFLDKFLFDYVQKNVKGGRQHPQNIRNLSKYIARKGGYRLERERIKQAAPKWLERLDREYGGYKDSDLSFTLLIHYCDYMQEEGLTKDTKLHDDMMAELGKLGNVRSLRNNVAHQITNVTRESFQKVIQMTPPALMAIFTQMLTLVYGGKVKEALTTYSRINSWLEEALEIHE
>NZ_CP014239.1|WP_061945248.1|1021219_1021975_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MLRRFEAELRLPDGARAPSSMGSILHGALIEQLPEDYADYLHTENLRPYSQSIRWDRARERVIWRIGTLDRTAGEIIGAVLQSLEHIHLRQKGYTVDMQNIQCIEERGYQDIADEYFRAETAPRGAEIHFLTPTSFKQGGAYIILPESALILQSLLARWNRFCPDIRIEEDDLAQTLAAHTRLTRYALRSAAFSVEGYNIRGFRGQIALQFAGSDMVRRILGTLLTFAPYAGLGIKTALGMGAVETDIWKG
>NZ_CP014239.1|WP_061945250.1|1021958_1023191_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MKGDIIRQTYEIKCIAPVHIGSGEELRTFEYLYNRDKLELCLLNESKWLAFLETRGLTEAFIKYVEIEGAGRSPRNLLEWLTANRVTEADLRKAGAIRRKVPVAQLSEKKYKNRKPTLNKVVCHLVRSDNAQPYIPGSSIKGTLRTGILHHFIRKDPARFRPYWQEICSVRGSLKEKGHKWNEIILRLEQELLHTLTYEDTERGDAAASALRGLCVSDAMLVGCAAKAPTIIVQKIDATTLIKPGERRGESPIVLFRECIPADSRLRFTITANLPMLRAAGIDSLPSVLNMLRTCTLDGLTRQQRVFEAIDAKYYGALFDDITAFKANALLGGGTGFLTKSLIYALADKENDARRFAAAYFDEQFTNPSHKHMETDVRLTPRTLKRAQTDGADWIMGLCSITGVGNAETL
>NZ_CP014239.1|WP_061945252.1|1023187_1024198_-|hypothetical-protein
MSYVIYPLHFETAVHFGQPGRGGRLDEACMEYPADVLFGALCAELAAAGEEESLVRLAEEVERGDLRLSDLLPWQSRKSDGAMALFLPRPVLRVERKEREWREDYQTTCANATLRKKQKKLKYIRASRMQDYIRAMERGIPFEENDFDAAFGIEFLCQRVNTRGEEPLPYYVAQFTFAARAGLFLIARVRDAEMGAWLHRLLTWLGMAGIGGKRTSGYGKFRVGEIIHTDADDGGDIAALRDMLAADRAPWQLALAPVLPTADDLAAVKAGAYRLRRAGGFISYPTHAAEKKNSVYLLDAGSCFPVRIGGTCSTLGTHDGHPVWRYGYGLYAGVTA
>NZ_CP014239.1|WP_083501203.1|1024194_1024929_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MEQKNTRQRALKGKLDIGAILRLETGLHIGASSDFAPIGAVDSPFLRDPMTKRPIIPGSSLKGKIRTLLARSFSTDEYFLNKIDEDSPVIQRLFGSAAQSGAGGLGARLQFSDIRMTEASCQRFAAMELDTYIGEIKFENTISRISAAANPRQIERVPAGAEFDFRLVYNIEDEGDLAEDLQILADGIRLLQMDYLGGHGSRGYGRVLLRDFHVKHFTIHAENAMTQERLQRIAEMLQKGGGSM
>NZ_CP014239.1|WP_061945256.1|1024931_1025357_-|type-III-A-CRISPR-associated-protein-Csm2
MAETIKKLTETDDIAGKAEKIILGLKNDRLLGGTNGLTTNQIRKFLTAVNTLTNKITLYRHQQEQTRELSEDLAKEVRFLKVKLAYQVARGNKGVKQFAKDTQLKEYIDTVGTDLKEYMAFAQFIEALVAYHKFYGEKEGE
>NZ_CP014239.1|WP_061945258.1|1025349_1027770_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MEDLCERIERAALLRTVRILAARAHPAAHDAGTAFLAEYCAEDAALLQLLRADAGASDDAIGWILDAAQRLAGAGTSASEHAAPHEPTHLESVFNRFGAANGSKEGFPIRSLTDGAGMLFPRPVGDLDDAVRGHREVCDRLARHFARKSPVHMPLGELLRVLEETMSYVPSPAGADIALYDYARMTAAYAAALHRYAAAQDIHSAHTYEERGGEALPAFLLVSADISGIQPFIYAIPSKGALKSLRGRSFYLEILLENIVDEILSACGISRSALLYTGGGHFYLLLPNTVDVQNLLTRCHTEANSWMLEHFGSSLYLAMAWTACTGAEFAGQGTQEAFHRVSEGLSAEKLCRYSEDQLAAMFVPESAWNKTRDKDRECAVCHTSTTHLMPYSADSSIEACGVCSHLFTFGERILTKNAFCVSAERSAEALSLPGIGRTLYLTAEELDDVDRLSYKIERIYAKNAAYTGDLPAAHLWLGDYSARENKALLEMENLAQRSGGTEDSKGIPRIGVMRADVDNLGAAFLAGFPSEYVTMTRTAALSQRLSLFFKHYINLLCSGSVSGVGDRQKTAPFSLFGREKKAERDVHIVYSGGDDIFLLGAWDDIVELAVDLRRAFLRFTGGKLRFSAGLGFFKDKCPVAEMARRTGDLESRAKDQRGADGRPQKDSVALFGAVTEGRSLAEFERHTPIYGWDVFIDHVCGEKLAFLRAHCIFEEGAKGERLSLGKSAVYRLLTLLEQDGQIQLARFAYALARLAPPAQSPAQEAYRRVRTQLYEWYRDPAERRQLSTALQLIIYSIREKGEGSNG
>NZ_CP014239.1|WP_061945260.1|1028068_1028473_-|antitoxin-HicB
MDKIVYPAVFRPDECVGGYTVDFPDLLGCVTEGDTLHEALYMASDALGLYLYTLKADKKPFPPATDPADIETHGRDFTTLIEWDEEAYLRRTDNRSVKKTLTIPAWMDTLAREHNINFSQLLQNAIRRECGMEA
>NZ_CP014239.1|WP_083501155.1|1028490_1028676_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MMTSKELLKILKKDGWQIERINGSHYILKHPTKPGMPIIPMHNKDLRIGTFKTILKQAGLE

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Crispr_ID: NZ_CP014239_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014239_2

1177636-1177739

Orphan

Consensus_repeat	Method
GTCCCAACACACACAATGCTGCGTGCGGCATTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014239_2

>merge|NZ_CP014239|2|1177636-1177739|CRISPRCasFinder
GTCCCAACACACACAATGCTGCGTGCGGCATTGAAACTCCCTTCTCGTGCCGTTTCGGCAACTCATGGTAGTCCCGACACACACAATGCTGCGTGCGGCATTGA

>NZ_CP014239|2|2|1177636-1177739|CRISPRCasFinder
GTCCCAACACACACAATGCTGCGTGCGGCATTGA	AACTCCCTTCTCGTGCCGTTTCGGCAACTCATGGTA
GTCCCGACACACACAATGCTGCGTGCGGCATTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014239.1\|WP_061945468.1\|1186171_1187623_-\|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl\|CDD\|273037
NZ_CP014239.1\|WP_061945451.1\|1173824_1174298_-\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|224854
NZ_CP014239.1\|WP_061945466.1\|1184702_1185845_-\|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl\|CDD\|235541
NZ_CP014239.1\|WP_061945457.1\|1181905_1182247_-\|nucleotidyltransferase	unknown	unknown	gnl\|CDD\|224583
NZ_CP014239.1\|WP_157064456.1\|1169924_1170806_-\|N-acetylneuraminate-lyase	unknown	unknown	gnl\|CDD\|179749
NZ_CP014239.1\|WP_061945453.1\|1178287_1178980_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014239.1\|WP_083501205.1\|1181616_1182012_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|225236
NZ_CP014239.1\|WP_061945450.1\|1172768_1173566_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|238693
NZ_CP014239.1\|WP_071884690.1\|1166847_1167747_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NZ_CP014239.1\|WP_061945449.1\|1171623_1172772_-\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|238434
NZ_CP014239.1\|WP_006305399.1\|1187959_1188094_+\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|179004
NZ_CP014239.1\|WP_061945461.1\|1183364_1184483_-\|DNA-replication/repair-protein-RecF	unknown	unknown	gnl\|CDD\|234608
NZ_CP014239.1\|WP_061945463.1\|1184485_1184701_-\|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl\|CDD\|379097
NZ_CP014239.1\|WP_061945455.1\|1179336_1181394_-\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl\|CDD\|235542
NZ_CP014239.1\|WP_061945459.1\|1182259_1183168_-\|DUF721-domain-containing-protein	unknown	unknown	gnl\|CDD\|377496
NZ_CP014239.1\|WP_061945448.1\|1170888_1171560_-\|N-acetylmannosamine-6-phosphate-2-epimerase	unknown	unknown	gnl\|CDD\|234907
NZ_CP014239.1\|WP_061946952.1\|1176623_1177253_-\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|225462
NZ_CP014239.1\|WP_061945446.1\|1168316_1169822_-\|sodium:solute-symporter	unknown	unknown	gnl\|CDD\|271386
NZ_CP014239.1\|WP_061945452.1\|1174540_1176259_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014239.1\|WP_061945444.1\|1167765_1168215_-\|DUF386-domain-containing-protein	unknown	unknown	gnl\|CDD\|377217

Protein	Function_ID	Function_description	E-value
NZ_CP014239.1\|WP_061945457.1\|1181905_1182247_-\|nucleotidyltransferase	gnl\|CDD\|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	1.7215e-15
NZ_CP014239.1\|WP_061945451.1\|1173824_1174298_-\|IS200/IS605-family-transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.63717e-48
NZ_CP014239.1\|WP_061945466.1\|1184702_1185845_-\|DNA-polymerase-III-subunit-beta	gnl\|CDD\|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	5.64026e-118
NZ_CP014239.1\|WP_061945444.1\|1167765_1168215_-\|DUF386-domain-containing-protein	gnl\|CDD\|377217	pfam04074, DUF386, Domain of unknown function (DUF386). This family consists of conserved hypothetical proteins, typically about 150 amino acids in length, with no known function.	9.62229e-47
NZ_CP014239.1\|WP_157064456.1\|1169924_1170806_-\|N-acetylneuraminate-lyase	gnl\|CDD\|179749	PRK04147, PRK04147, N-acetylneuraminate lyase; Provisional.	2.61881e-175
NZ_CP014239.1\|WP_061945468.1\|1186171_1187623_-\|chromosomal-replication-initiator-protein-DnaA	gnl\|CDD\|273037	TIGR00362, DnaA, chromosomal replication initiator protein DnaA. DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP014239.1\|WP_061945448.1\|1170888_1171560_-\|N-acetylmannosamine-6-phosphate-2-epimerase	gnl\|CDD\|234907	PRK01130, PRK01130, putative N-acetylmannosamine-6-phosphate 2-epimerase.	2.72623e-109
NZ_CP014239.1\|WP_083501205.1\|1181616_1182012_-\|DUF86-domain-containing-protein	gnl\|CDD\|225236	COG2361, COG2361, Uncharacterized conserved protein [Function unknown].	1.55932e-16
NZ_CP014239.1\|WP_061945450.1\|1172768_1173566_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	7.40805e-129
NZ_CP014239.1\|WP_071884690.1\|1166847_1167747_-\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	3.50939e-61
NZ_CP014239.1\|WP_061945449.1\|1171623_1172772_-\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	3.97147e-139
NZ_CP014239.1\|WP_006305399.1\|1187959_1188094_+\|50S-ribosomal-protein-L34	gnl\|CDD\|179004	PRK00399, rpmH, 50S ribosomal protein L34; Reviewed.	1.97483e-09
NZ_CP014239.1\|WP_061945461.1\|1183364_1184483_-\|DNA-replication/repair-protein-RecF	gnl\|CDD\|234608	PRK00064, recF, recombination protein F; Reviewed.	4.70064e-118
NZ_CP014239.1\|WP_061945463.1\|1184485_1184701_-\|RNA-binding-S4-domain-containing-protein	gnl\|CDD\|379097	pfam13275, S4_2, S4 domain. The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4.	9.79652e-22
NZ_CP014239.1\|WP_061945459.1\|1182259_1183168_-\|DUF721-domain-containing-protein	gnl\|CDD\|377496	pfam05258, DUF721, Protein of unknown function (DUF721). This family contains several actinomycete proteins of unknown function.	1.12389e-12
NZ_CP014239.1\|WP_061946952.1\|1176623_1177253_-\|NAD(P)H-binding-protein	gnl\|CDD\|225462	COG2910, COG2910, Putative NADH-flavin reductase [General function prediction only].	2.08385e-71
NZ_CP014239.1\|WP_061945446.1\|1168316_1169822_-\|sodium:solute-symporter	gnl\|CDD\|271386	cd11495, SLC5sbd_NIS-like_u3, uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain. Proteins belonging to the same subfamily as this uncharacterized subgroup include i) NIS, which transports I-, and other anions including ClO4-, SCN-, and Br-, ii) SMVT, which transports biotin, pantothenic acid and lipoate, and iii) the Na(+)/monocarboxylate cotransporters SMCT1 and 2. SMCT1 is a high-affinity transporter while SMCT2 is a low-affinity transporter. This subgroup belongs to the solute carrier 5 (SLC5) transporter family.	0
NZ_CP014239.1\|WP_061945455.1\|1179336_1181394_-\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl\|CDD\|235542	PRK05644, gyrB, DNA gyrase subunit B; Validated.	0

>NZ_CP014239.1|WP_061946952.1|1176623_1177253_-|NAD(P)H-binding-protein
MNIAVVASNGKASRAIIEELVARGHEVTAFARHENQSAAKHFVQKDILDLTKGDLAGFDVVVDGFGAFTPETLPLHTKTSQHLADLVAGTNTRLYIVGGAGSLYVDASHKMQLLDTPEFPAVFYAIAKAQTEELAALRERKDAKWVFVSPAADFRPDGEKTGAYLLGGEELTLSAAGESIISYADYAVGMVDLIESGEHIGTRVSLVQK
>NZ_CP014239.1|WP_061945452.1|1174540_1176259_-|hypothetical-protein
MSDTIYIEPDLSYLEDRLDALGDFVGAAHAEIHAVGRSVDDLRGDVETLTQDFHAYAAKQERTNRIQLAEIRLVKLRQEIEHRFGHYAEIRRMARGILEANDLAVVRRDTLRAAAEELMLHAPGYWLAPALVALAAWISDEEEVANRACAEALHRDDERTSIFFALVCRRFGRKEASLHWLQRYFAGLDGGALDRKAAIVIDAYVSGLLGRDADGLIRRRIDGWIDRFSRVYSFADAQEKRWYEAMKAMCPAPPAEGSFPYLRVHARSVSGALEHTLSCARLYEKLSTHFQQIVTQTAPPRTLKQQLDSILERLAADFDAAEKPLHMESILEKLVIHEGGREDRARKILAEKVKAFDERRDFMQLLSDAAMHPQEMQASPALQKMALALGRDSILSAFRDIVAENRADIPQTIKFRILAFDNETEDGSNEEKLLRLFVTWNDIKRMIRMRPYELSSQEKLFRWIWLLPVLLGLYGGEVYWTALGIAAGGVIFNAYIKAKKRMDSIHARITEEYQKQEEEGTQMLRGVIAEIVDYRTEIARLDAESEKVIDFLQGLNPAQFMASADGSRRVQV
>NZ_CP014239.1|WP_061945451.1|1173824_1174298_-|IS200/IS605-family-transposase
MSKQQNADTHSLAHTKWNCKYHVVFAPKYRRKVFYEGKRLEIREILRKLCAWKGVEIIEGEICPDHIHLLLSIPPKISIASFMGYLKGKSSLMIFPKYGNMKFAYRNREFWCKGYYVDTVGKNTKAIKEYIADQLKKDREQDQLSLFDPRDPFMGGK
>NZ_CP014239.1|WP_061945450.1|1172768_1173566_-|glucosamine-6-phosphate-deaminase
MLYCRRFRTSFIERRIALRIIYTDTYQNMSKEAAKILAGQLWVKPDSVLGLATGSTPVELYQNLVWLHEAVGLDFSEATSFNLDEYVGLPEDDPQSYHRFMHENLFDHVNIRKDHIFFPNGMAKDADAEAARYEAAIAAAGGIDMQLLGIGRNAHIGFNEPGEAFARTTHKVVLKESTIEANSRFFSSPDEVPREAMSMGIGTIFHARHIVLMASGAEKAEAVRDAVCGTITPRVPASILQLHPQVTLIVDREAGALLRESSDTK
>NZ_CP014239.1|WP_061945449.1|1171623_1172772_-|N-acetylglucosamine-6-phosphate-deacetylase
MRAIQNGVLILPSADGHFTAQEGLVLCYDERITNILPAAEFHAADAEMVIDAAGAYVAPGFLNVHIHGCDGADTMDEDADALRRIAAFQARTGVTSFLPTTMTCAFDAVERALVRIRRAMNADGTGARVLGAHMEGPFISPAKKGAQDEQYILPPAFAKIAPYADVIKIITIAPEMLTEEDFIAQCRTHGIIVSLGHTAADYDTARTAIRRGAGHITHLCNAMTGLNHRRPGVLGAALDSDANCELIVDNVHVHPAMQRIIYAAKRGAHIIPITDSLRACGCGDGVSELGGQKVFVKGTLATLADGTIAGSVLCLNHGLSIFRENTGASIPAVVETATRTPAEELGVYDRLGSLTVGKYADIAIFDEQFRIHRTVIGGRDCF
>NZ_CP014239.1|WP_061945448.1|1170888_1171560_-|N-acetylmannosamine-6-phosphate-2-epimerase
MNFFDKVKGKLIISCQALADEPLCSPFIMGRMARAAKEGGAVGIRAQSVADIDEIRAVTQLPVIGLIKQNYADSEIYITPTMREVEALIGTGCEMIALDMTARERPQETDVRDLIARIHAAHRLVLADISTYEEGMKAAELGADAVSTTMSGYTPYSPQIAGPDFELMQRLAKDAPVPVFAEGRINTPEELVQAMQTGVFGAIVGSAITRPQMIARRFTEAIA
>NZ_CP014239.1|WP_157064456.1|1169924_1170806_-|N-acetylneuraminate-lyase
MIMKDLKGLYSALLCSFHEDGTLNEKGLRQIIRHNIDHNKMDGLYVGGSTGENFMLSTDEKKRIFEIAKDEAKDDVTLIAQVGSINLKESIELAKFATDLGYDALSAVTPFYYKFSFDEVRHYYESIIADVDNRMIIYFIPFLTGVNISIPQFEKLFSNKKIVGVKFTQGDFYLLERMRKAFPDKLIFAGFDEMLLPATVLGIDGAIGSTYNVNAARARQIYDLAHANKISEALEVQHVTNDLITDILDNGLYGTIKLLLAEQGVEAGYCREPMKAYTPEMRARAKEIYKKYF
>NZ_CP014239.1|WP_061945446.1|1168316_1169822_-|sodium:solute-symporter
MHEGFTWIDTAVLIIYLLGVLLAGLYYSKKEMKGKEFFKGDGTIPWYVTCVSIFATLLSPISFLAIPGNSYHGSWIFWWAQLGMLFAIPLTIRYFLPIYSRLEIDTAYHYLQKRFESGKLRILGALMFIVYQLGRMSIIMYLPSIALAEVTGIDVNLLIVVMGVIAIIYSYSGGLKAVLYTDFIQGTVLIVGIALSLVVMIGSIHGGWGTVWDTLTTGHKFLLENEVWFSPDIVSSSVFITFIGGGLVTFASYVSSQDIVQRFTTTTDMKQLRKMTLGNGVISIFAATVFFLVGTALFVFYQQNPGLLMTDRRDLVLAAYITYELPTGLTGILLAALFAAAQSTLSTGINSVATSWVLDIQSVLHPEMPMKKQTRIAQFISLGIGILSIVVAIIMAGSDIRSAYQWFNSFIGLALGALAGVFVLGAFSRHANAAGAVAGFLVSTAVVIYLKYFVPSVSFWSYTLITIALTLGVGTIVSRLIAPGYTAPAGTTVYDTRGASH
>NZ_CP014239.1|WP_061945444.1|1167765_1168215_-|DUF386-domain-containing-protein
MIYGSIHHEDTYSFLPPRIRQALDFARTHDLGALPTGRNEIAGDDVYVNIAHYTTGERSEKIWEAHRAYIDIHVLAEGTEKIDVSLIERMETHPYEADKDYVPADGAATQTTIMRPGDFLVCFPEDVHRSGVKVDAPAPLKKGIFKVRV
>NZ_CP014239.1|WP_071884690.1|1166847_1167747_-|ROK-family-protein
MYICIDIGGTDIKYGVMDAAGEFAVHGTLPTEAKAYGGPGIVRKVSDLVRETCGTYDVRGVAISTAGMVDPATGEIVYALEESIPQYRGVNWKAIMRENFDLPASVENDVNCAALGELWKGAGRGASSLFAMTVGTSIGGCLIMDGRVVHGVSRSAGEIAYMRVPGGRLHERCSAAGLVSAVCCANGLPAGSIDGRFVFDLLAKGDPAAQEEVALLIDSLADAITNVVCVVNPERIVLGGGIMAQEAVLRPLLEAALRDRLPPIVDEATTIAFAATQNNAGMLGALYHFLQEQESAIPG
>NZ_CP014239.1|WP_061945453.1|1178287_1178980_-|hypothetical-protein
MKQFLDQLAVPRGDWTALFSACLGKMISVQQACAEYVVKNEDWNVDLARGVISFGTREYPLQFIGSESASSGTWLWGWENINDFPEKIIRLARETREFGAAQQIEALTTDEFDLNDTYNGHNLSIVACGLADGYAYYRCPHDGGAFFVGIFHVPDAVFDPVDFPRFISTVSQCIQQFDVDHRILVEGFLRWNQTPYEWHGSRITAHFTQDLIIAFEDVDGAQRISTMRSI
>NZ_CP014239.1|WP_061945455.1|1179336_1181394_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MAKKNNPNETTDEQAEIRPLTPEEAKEAAEMADAPDLTGIAISEEEMGDEVTAVDADYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVYEVVDNSIDEALAGYCDTVGVTVHKDNSITVTDNGRGIPVDMHESGMPAVEVVLTVLHAGGKFGGDGYKVSGGLHGVGVSVVNALSTEMDVEVRRDGKIFAISFSRGVTTTKLHEIGTSDTTGTRVHFVPDPEIFTVTTYSFDTLKHRLRELAFLNHGITITLTDERGAEVRSETFHFDGGIRSFVSHLNRKKETINEEPIYFNGVKDDTVVEIAMQYNDSYQENIYSFVNNINTEEGGTHLAGFKIALTRAANDFARRLNVLKDKDGNLSGEDVREGLTAVISLKVREPQFEGQTKTKLGNSEVRGIVDSIVTEGLTEYFEENPAVTKKVLDKALMASRAREAARKARELTRRKNALEVSSLPGKLADCSVKDPDQCEIYIVEGDSAGGSAKQGRDRRFQAILPLRGKILNVEKARLDKIFANAEIRTMITAFGTGIGEEFDLAKRRYSKIIIMTDADVDGAHIRTLLLTFFYRYMKPLVDHGHVYIAQPPLYQIRKDKKHFYTYSDEEQAKKLDEIGRDGVTIQRYKGLGEMNPEQLWETTMNPEGRTMLRVGAEDAETADELFTILMGDKVEPRRQFIEENAKLVRNLDI
>NZ_CP014239.1|WP_083501205.1|1181616_1182012_-|DUF86-domain-containing-protein
MSIRFLQNMWKETRCCSMMLSPKDAQILQIIVQYCEDIDEAQERFGKTRDDFIKDRLFQHACSMALQTIGEASRSFSDAFITEHQEVAWKLIKGMRNFFAHSYHISIDMDKVWMMVHRDIPLLKAYCVRNH
>NZ_CP014239.1|WP_061945457.1|1181905_1182247_-|nucleotidyltransferase
MILSIDEIRDKIRPICEKYKIEKVWLFGSYARGEAREDSDVDVYAASGNHVSLLDLIAFRMDLEDAVAKDVDMITRIPNEYPIFAKYVERDKVLLYDAQSEGRTDSANYRSVL
>NZ_CP014239.1|WP_061945459.1|1182259_1183168_-|DUF721-domain-containing-protein
MRTTLGTAGADDDVRAAIRRLGPSFERDYITHTTLSHWADIMGEMVARRVHAVAVKDKKLFLYAPDAVWKNEMRMSAPEIVQRVNNYAGGRMVTEIAFARTMRPALQTADDAAAETPAAYRRALAQTGLTDAEIARGASLAARIEDSDLRTHIERAYLTTRKARNLKEARGLTPCPVCGRLTSGVCMDCRRSEERGLRREVRAILRREPWAKLADITRRIPSADALMVGSERADLIRSIAGRTEYTAQDSENARLLTMLHRGLPPEQVTPKKIQSTFWELRNELITTREFWEEMKKRRAKKS
>NZ_CP014239.1|WP_061945461.1|1183364_1184483_-|DNA-replication/repair-protein-RecF
MQITELTLRSYRSYETLHLAFDLGVQIFLGANAQGKTNIIEALYYAAFGRSHRTSSDAELIRAGADGAHIGLSFRRHDVPGELSFTFARGARRRITYAGESLRQRDLVGLLPMVLFSPEDLFLVKGAPALRRRYLDAELSQASPAYYGELLRYTRILKQRNAVLKDIRERLAAPDDLPPWDAQLARSAAYIVTRRIAAVAQLGALSARVQAVLAAGEELALAYEIAGAGAEDFAEDDMTESLHLWYNKMLCEGRARDIARAATGVGPHLDDLVLRVGGMSLRSYGSQGQQRTGALALKLAELFYLQENIGEAPILLLDDVMSELDADRRRALLDFIRHEHIQTFITATDAAYFPAERMGTYRYVEAGTVREN
>NZ_CP014239.1|WP_061945463.1|1184485_1184701_-|RNA-binding-S4-domain-containing-protein
MMDIAIHTDTIQLDQFLKLAGAVASGGEVKALLAEGIILRNDVPETARRRKLVPGDVITINSSDAYRVVRV
>NZ_CP014239.1|WP_061945466.1|1184702_1185845_-|DNA-polymerase-III-subunit-beta
MNITLPKSDLIAALQIVSKGLSTKPQTPILSGVYMNAREGQLELQTTNYELGFIMTIPAEIHGTGTAVLPGKYLTEFARKLPAEEVSINTESSDGLAEIRSGTVRFTLRTMEVTDFPVLQRMDGTLQFTIKDRVLARLVKKSAFACLKEEQRDRRPIFTGCQLEVEGREVTFAATNVHRLAVKSEQLEEEAGQIRVIIPARFLEEVTRTMNSDVPSDVHMSCSYNQISVSFDNIYMTSRLIEGAFPDYRRVIPQDANIRTKVTLDVAAFSAAVDRASLIARTDQYNIVKLRFADGMMCISSNSPEIGEAEETITAQVEGDDVTIAFNASYLMDAMKSLDSDTCILSLQGSNEQGVNLSPITIREEADPNYIYVVTPVRTH
>NZ_CP014239.1|WP_061945468.1|1186171_1187623_-|chromosomal-replication-initiator-protein-DnaA
MSEEKNLADLWQKVLDKTSGIIHEDAVKKWILPIVPVSLNDKELLLAVGEDIQKQYVESRLGALFGDVIQKALGAGYTFRIVIDPAAASQKEPPAAKEIPVEPAMAEEAAAGHIAADEQATYPTQGSLPLTPPETHAPAPDDATTLNPKYTFEAFVTGRSNQFPYAMAKAVADAPGLPSHNPLFIYGGVGLGKTHLMHAVGHKILADDPKKRVLYIASTDFTNEFIRSIREKNMDAFREKYYHIDVLLIDDIQFFAGQEQTQTEFFQTFNKLRDNGSQIILTSDRQPQDVKGLEDRLISRFAGGAPVDIQPPEFETRVAILQKKAQSEDVDIPADVVTYIASRVDSNIRELEGALTRLIKYASMMRMPINETTCVAALGNYLRGEKGRRITMEMIERIVCTHFKVTSEDIRSSKRSNDIAYPRQIAMYLCHEMTEVSWPTIGGFFNRDHSTVIHAHKKIQSLTESDPATDALIKSLSIQVRGI
>NZ_CP014239.1|WP_006305399.1|1187959_1188094_+|50S-ribosomal-protein-L34
MKRTFQPNNHWRKKTHGFRERMKTKGGRLVLKRRRQRGRKKLSA

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Crispr_ID: NZ_CP014239_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014239_3

1205420-1205657

Orphan

Consensus_repeat	Method
TGCGGCGCGATCACCTGCGTGCCCGTCTTGTCGATGAAGCCGA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP014239_3

>merge|NZ_CP014239|3|1205420-1205657|PILER-CR
ACCTGCGTGCCCGTCTTGTCGATGTAGGCGAGCCCCTTTTTCCCGCGCACGGCGGCCAGCCCCTCGCTGAATCCCATGGGGATGTCCCGATACTGCGGTGCGATCACCATCGTGCCCGTCTTGTCGATAAAGCCCCACTTGCCCCCAACCTCGACGGCGGCCAGTCCCTCGGAGAAAATGCCCGCCGAGGCGTACTGCGGCGCGATCACCTGTGCGCCCGTCTTGTCGATGAAGCCGA

>NZ_CP014239|3|2|1205420-1205657|PILER-CR
ACCTGCGTGCCCGTCTTGTCGATGTAGGCGAGCCCCTTTTTCC	CGCGCACGGCGGCCAGCCCCTCGCTGAATCCCATGGGGATGTCCCGATACTGCGGTGCGATC
ACCATCGTGCCCGTCTTGTCGATAAAGCCCCACTTGCCCCCAA	CCTCGACGGCGGCCAGTCCCTCGGAGAAAATGCCCGCCGAGGCGTACTGCGGCGCGATC
ACCTGTGCGCCCGTCTTGTCGATGAAGCCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014239.1\|WP_061945488.1\|1198986_1200546_-\|WG-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379719
NZ_CP014239.1\|WP_061945510.1\|1212962_1213748_+\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235933
NZ_CP014239.1\|WP_061945478.1\|1194226_1195246_+\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|235136
NZ_CP014239.1\|WP_061945500.1\|1206459_1207290_-\|AmmeMemoRadiSam-system-radical-SAM-enzyme	unknown	unknown	gnl\|CDD\|275136
NZ_CP014239.1\|WP_061945480.1\|1195235_1196165_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP014239.1\|WP_061945504.1\|1209031_1209796_-\|DUF554-domain-containing-protein	unknown	unknown	gnl\|CDD\|377371
NZ_CP014239.1\|WP_061945508.1\|1212106_1212949_+\|5-dehydro-4-deoxy-D-glucuronate-isomerase	unknown	unknown	gnl\|CDD\|179169
NZ_CP014239.1\|WP_061945486.1\|1198466_1198868_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014239.1\|WP_061945502.1\|1207286_1208669_-\|AMMECR1-domain-containing-protein	unknown	unknown	gnl\|CDD\|235170
NZ_CP014239.1\|WP_083501161.1\|1203066_1203738_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP014239.1\|WP_061945490.1\|1200819_1201251_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014239.1\|WP_061945484.1\|1197830_1198241_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014239.1\|WP_061945512.1\|1213776_1214742_+\|2-keto-3-deoxygluconate-transporter	unknown	unknown	gnl\|CDD\|235384
NZ_CP014239.1\|WP_061945514.1\|1214962_1216324_+\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NZ_CP014239.1\|WP_061946953.1\|1209896_1210844_-\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl\|CDD\|235577
NZ_CP014239.1\|WP_061945482.1\|1196161_1197268_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP014239.1\|WP_157064457.1\|1210848_1211772_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|238571
NZ_CP014239.1\|WP_061945492.1\|1201369_1202806_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP014239.1\|WP_061945516.1\|1216694_1217966_-\|sugar-phosphate-kinase	unknown	unknown	gnl\|CDD\|226939
NZ_CP014239.1\|WP_061945496.1\|1203892_1204648_+\|creatininase-family-protein	unknown	unknown	gnl\|CDD\|376872

Protein	Function_ID	Function_description	E-value
NZ_CP014239.1\|WP_061945488.1\|1198986_1200546_-\|WG-repeat-containing-protein	gnl\|CDD\|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.60614e-12
NZ_CP014239.1\|WP_061945478.1\|1194226_1195246_+\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	2.64443e-49
NZ_CP014239.1\|WP_061945500.1\|1206459_1207290_-\|AmmeMemoRadiSam-system-radical-SAM-enzyme	gnl\|CDD\|275136	TIGR04337, Radical_SAM, AmmeMemoRadiSam system radical SAM enzyme. Members of this protein family are uncharacterized radical SAM enzymes that occur in a prokaryotic three-gene system along with homologs of mammalian proteins Memo (Mediator of ErbB2-driven cell MOtility) and AMMERCR1 (Alport syndrome, Mental Retardation, Midface hypoplasia, and Elliptocytosis). Among radical SAM enzymes that have been experimentally characterized, the most closely related in sequence include activases of pyruvate formate-lyase and of benzylsuccinate synthase.	1.69409e-85
NZ_CP014239.1\|WP_061945504.1\|1209031_1209796_-\|DUF554-domain-containing-protein	gnl\|CDD\|377371	pfam04474, DUF554, Protein of unknown function (DUF554). Family of uncharacterized prokaryotic proteins. Multiple predicted transmembrane regions suggest that the region is membrane associated.	8.00519e-73
NZ_CP014239.1\|WP_061945512.1\|1213776_1214742_+\|2-keto-3-deoxygluconate-transporter	gnl\|CDD\|235384	PRK05274, PRK05274, 2-keto-3-deoxygluconate permease; Provisional.	4.52448e-148
NZ_CP014239.1\|WP_061945508.1\|1212106_1212949_+\|5-dehydro-4-deoxy-D-glucuronate-isomerase	gnl\|CDD\|179169	PRK00924, PRK00924, 5-keto-4-deoxyuronate isomerase; Provisional.	7.19024e-179
NZ_CP014239.1\|WP_061945502.1\|1207286_1208669_-\|AMMECR1-domain-containing-protein	gnl\|CDD\|235170	PRK03881, PRK03881, hypothetical protein; Provisional.	0
NZ_CP014239.1\|WP_083501161.1\|1203066_1203738_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	4.9003e-31
NZ_CP014239.1\|WP_061945510.1\|1212962_1213748_+\|gluconate-5-dehydrogenase	gnl\|CDD\|235933	PRK07097, PRK07097, gluconate 5-dehydrogenase; Provisional.	2.63241e-173
NZ_CP014239.1\|WP_061945480.1\|1195235_1196165_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.43375e-97
NZ_CP014239.1\|WP_061945514.1\|1214962_1216324_+\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NZ_CP014239.1\|WP_061945492.1\|1201369_1202806_-\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.9906e-49
NZ_CP014239.1\|WP_061945482.1\|1196161_1197268_+\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	9.95185e-33
NZ_CP014239.1\|WP_157064457.1\|1210848_1211772_-\|sugar-kinase	gnl\|CDD\|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	2.98694e-91
NZ_CP014239.1\|WP_061945496.1\|1203892_1204648_+\|creatininase-family-protein	gnl\|CDD\|376872	pfam02633, Creatininase, Creatinine amidohydrolase. Creatinine amidohydrolase (EC:3.5.2.10), or creatininase, catalyzes the hydrolysis of creatinine to creatine.	1.70972e-64
NZ_CP014239.1\|WP_061945516.1\|1216694_1217966_-\|sugar-phosphate-kinase	gnl\|CDD\|226939	COG4573, GatZ, Predicted tagatose 6-phosphate kinase [Carbohydrate transport and metabolism].	2.6158e-06
NZ_CP014239.1\|WP_061946953.1\|1209896_1210844_-\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl\|CDD\|235577	PRK05718, PRK05718, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional.	7.79687e-80

>NZ_CP014239.1|WP_061945496.1|1203892_1204648_+|creatininase-family-protein
MLNELWRMTAHQVKEGNFKKAVLAVGACEAHGQHLAEGCDTIVSYKLGKAIADELGDMLVLPPIPVGYSGHYDSFPFTLTLQYDTVTQVIYDIVESVLRNGIDTILIINGHDGNIAPIEVASRKIKEKYPSARIAALDQWWVTAGELLPKGTFEVWNGLGHAGEGETSIAYYLFPEWCEPEQATCRVPKNLPELMGIKWDFSELTNTAQTGDATKGTAEKGEKMFKVLIEYCTKTIKALDAVDWQFEADQK
>NZ_CP014239.1|WP_083501161.1|1203066_1203738_+|GntR-family-transcriptional-regulator
MRARRCGMAMDAEQSGKHSITSTVLRALRKEICASAYADGQFITEAEVSQKYRVSKTPAREALTILCEEKLLCKIPRKGYMVKKLSLEELRKLYQFRNILERAIVEHAVRYADEEDLRNLDVLASAQVDTSHPEWIQEYHRVNSAFHIGLAALTRNNYLIDALRGVLNILQRDLIEDMKYIGVEKTLGEHRRIVEAVRRRDLTEALSITSQQINIIERKEHMS
>NZ_CP014239.1|WP_061945492.1|1201369_1202806_-|cytosine-permease
MMDKQSSVKENDPHNVPDDQEFMSEPVPMDKRHSTKDQIMVWIGFGYVVTGLVVGGQIGGQGGAGLPPLTAFLSVALGMGFLFFLTSFLGIASQKTGYNLSLLCRFSYGERGSNLPLAMMSLMTLGWFASIAGMIGQIWGAWIGNPSGVVVFDPNAHGFHGVAAITLEEFLSTFVWGLIFTYTAVRGMGAIEKVANIFAPFIMIVAIVMGFVYISQAGGLSPFLSKAGMLSGMSMGTAITAVVGSWIAGAIMGTELFRFNKNIRAVWWCAAACFIFTNPILNVVGYIGAVQTGDFNYVMYMLQVSIPVAILGVIVWTSALWTTDNGELYCNALYTGPVLRSYGFNVERKQVVIVIGVLGSILGSLAFYQLFFADFINVLGIMGPPIASPILADYFVSGRHRKYNAAALAYQPAIRWAGLLSFAIGAAIALYCSYGVTLPGEFPSGVFAMIVSFIVYIVIYRFLPDAVADQRILKQING
>NZ_CP014239.1|WP_061945490.1|1200819_1201251_+|hypothetical-protein
MMTSMIVLILFGVVACGAALWSMYCGLRGGATKKFLHFENGRLTVYYYSFPGMHEKTYALDQIREVRFTHHWVRSPVSHTGKMQIVLHDGTESRSFFYDGSVHMKKMVLATSLALMSLTTKELAEEFRRHGVRRIIIDPHLLE
>NZ_CP014239.1|WP_061945488.1|1198986_1200546_-|WG-repeat-containing-protein
MTKENEMTRMNMTRLCTAVAALSTALLLSTGIGQAAEKPQEELSSAVIMPNTARTVFQVQKNGKWSAVATDGTEVVPLVYDSIFTYAEGYLIVQKNGRLGIIRADGTQIVPTAYVNIKPLMDDIIVVRDEKGKVGAYDLSGALLLPAAYASIQPMGHGILCIGEEYHQYRLCRRDGSRLTDEIFYSVEPFSEGRAAVIRKKGEQYGYIDETGNMVIPPSYDRAEPFHEDRAAVNIDKKWGFIDRSGAMVIAPQFRKLGHPKGFHEGYALVMKGKKITFIDKAGKTPFKMQWSTACSFYDGLAEVSHSRGTRTLANLGSAVTSALSLAAGAPLYEDDGSIIDDGARRGYINTSGTEVIPSTNDYTTMFKDGIALVKVHGQWGAVDRSGTYIVHPQYSKMHYFCDDLAAVCDGRKWGYVGRDGIMHIPPAYDEADDFHEGLTRVRAADDVLIIDKTGQIAFHLPAGLEFPWHFSAGIAPIIKDGKWGFIDRSGSIVVSPQYSAVLRYDVLWMMGSSTYYSG
>NZ_CP014239.1|WP_061945486.1|1198466_1198868_+|hypothetical-protein
MKFDKIYVGRGIAAPTPVRRTTHLGEDTGDTFARILQEERDAAEAELQNPENSEPDTIVTRVLADGSVVTRAYKGARLISETTTHGNRLTPSKALIAEQATYLSGAAQSAAAMLASLTPQGAAEHTEHISNTL
>NZ_CP014239.1|WP_061945484.1|1197830_1198241_+|hypothetical-protein
MELEKIYGSGGAVPASSARRTHAKEDTSGTFARMLQNMREAKPVNSYGREDLEGDTVVTRVLADGSVITQIYKGTTLISETTTPGTNPEAGKALISERVEQLKLDEDAAQNPLLDSHAAQGAQGIAALIGTAVSSD
>NZ_CP014239.1|WP_061945482.1|1196161_1197268_+|ABC-transporter-permease
MTRILALLAKELIQMRRDPITIGVTFLLPVIYLVVFGFAISTDVRHQSTVVFDQSRSEESRSFLAAMTASGYFDLRYIAWSYDELNERIERGDAKIGVVFPPNLVQEANAGRTVPIQMIVDASDSIASTSAIAAATGLGMQVRPTAAHGASAAAPAYDVRIRAWYNPDAVTSYYMLPALMGIILSITMVVMVSMSIVREREAGTLEQLLVTPLHVWELLIGKILPYIILGYIQTTICVLIALAVFGVPLRGSILLLYGLTTLFLLASLTMGLMIASLAQNQLQAGLMSIATLLPGFLLSGFMFPREAMPTFFQYLSLAIPMTHYIEILRMIFLKGGGLTALYQQTAFLALFILVFFGTAVRKFKRSVI
>NZ_CP014239.1|WP_061945480.1|1195235_1196165_+|ABC-transporter-ATP-binding-protein
MEREPRADDAPVIETHDLTRVFGSYTAVDRLNLSVPRGAIYGFIGSNGSGKSTAIRMICGLLPPTSGTAFVLGCNTAVHPERARQALGYMSQRFSLYTNMTVRENMMFYGGLYGLSREERRTRVAEVIARMQLTDRADVLAGGLSGGQKQRLALGCAILHRPALLVLDEPTSAVDPTSRRLFWNLLSEMAGTERTTIFVTTHFMDEAEHCDEIAFLQRGKKIASGSPSALKEELPARLYVLPQDSAEEGEAALRAAGVPCDEVYVFGRQVRALVPRDTVLPEQLHAAPWDLTMEDVFIYYDRRQREAQG
>NZ_CP014239.1|WP_061945478.1|1194226_1195246_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MILRKGERCMKMKMARIVLLLLALILLAVFAYREYAAQELRAQLLTGTVEATRVEVSTKESGCIEELFLQEGMTVRAGDPAARIGRRDLDAAVLRDEAALAHAETSLQRTQSGNRAEEIRAAAERTNAARAAAEKADADYARGAELIAGGAISQQAFDGLREARDAANANLRAAQQEQALTESGSRPEDIRMAEEDVRRQQAILEIDASAVSDLTVRVPKDGIVLSKNYERGEFVRAGMPIATLIDPQDVWVKVYVPTDVLGDLRIGDPAKVYIDGQADPLDGTIKEISDAAEFTLRQSITKNERANLVFGVKVAVDNAAGILKPGMPADVDLEPRNGT
>NZ_CP014239.1|WP_061945500.1|1206459_1207290_-|AmmeMemoRadiSam-system-radical-SAM-enzyme
MTAVCSLCPHACRLREDETGFCRARTNVGGVIRPTNYGRLTALALDPIEKKPLYHFHPGRAILSVGSYGCNLACPFCQNADIAAADASIPTENVLPARLAALAQELSAAPHGSLGVAFTYNEPLISYEYIMDTAPLLHAAGLAVVLVTNGMICAEPLARLLPHVDAMNIDLKGWREDFYRRLGGDLMTVRGTITHAVRAGVHVEVTTLIIPAMNDSLADMDAEARWLAALSPDLPLHISRYFPRHRMHTPPTPIADIDTLTAVAARHLRYVHRGNC
>NZ_CP014239.1|WP_061945502.1|1207286_1208669_-|AMMECR1-domain-containing-protein
MSIVAAYAVPHPPLLLPEVGQGEERKLQLTLNAYERAMKEAAELAPETVIVASPHTVMYADYFHIAPGEMASGDFAAFGAPDLRVMADYDGPFAKELAKAASVEGIAAGGVGGRGAALDHGVMVPLSFLEPHTTDFRLVRVGVSGLSPKEHYVFGRCIARVAEELGRRAVFFASGDLSHRLTPDAPRGFAPEGPRFDKACMKYLEEGDFLKLLRMDPAIYQPAAECALRGLWMLAGVLDARALKIKKLSYQGTTGIGYGLVSFKVTREDPRRSFVERYEMLERRAREERRAAEDDYVRLARRAVETIVRTGKLPPVPAELPEEMTGRAGVYVTLTRDGTPRGTYGTFEPSAKSIADEITRNAAHAARNDTHVAPVTEEELDALDITVDVLSEPELVDGADALDPKTYGIIAESRGRKGVMLPAAPGTETAEEQLRAARKKGGIPEDAEIRIWRFTSERHA
>NZ_CP014239.1|WP_061945504.1|1209031_1209796_-|DUF554-domain-containing-protein
MAYNMPLRNGKRGGTMLPGIGIIANVAAIALGGVLGLGCGRFIAERVQETLMRACALSVMFLGLGGTLRTMLSVNADGQLALGGIYMMITSLIVGGLVGELLNIEARMTAFGAWLKRVSGSAGDTRFIDGFVTASLTVCIGAMAVIGSINDRLLGDPSVLFTKSVLDGVIIMLLTATLGKGCIFSSVSVGLFQGAIFALAGLLAPYMTDSALAGLSCVGNILIFAIGTNLLGLPNIRVANFLPALVIAALRGMG
>NZ_CP014239.1|WP_061946953.1|1209896_1210844_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MQKMSEIGLVPLVVLEDAACAKPLGEALAAGGIPVAEVTFRTDACLDIIRTMKEIPTLIVGAGTVHTVKQAEAAVAAGATFIVTPAYNPDVIDWCTAHEVDIVPGTVSPGEIEAVRARGIKFCKFFPAAAYGGTATLKSLAGPFADVQFLPTGGVSLDNMRDYLNLPNVAAVGGSFMTPGKLVKEQDWDGIAAVCRDAVQKMLGLRIGHVGIHTAGRAEAEELTDALCRLTGETKIAAGGGFFAGTIAEICAEPTPGDYGHLCIDTDDMPRALAYYARRGIALDPEYTFRDENGAVRLAYLKEKVGGFSIHLRRA
>NZ_CP014239.1|WP_157064457.1|1210848_1211772_-|sugar-kinase
MGLLIAQSEGDLSGVSGYDLAVAGAEFNVAIGAARLGHRVTYLTKLGKDPFGERIIHVLNENGIGNEFVSWSDEKRTGFMLKGRVHAGDPPIFYFRAGSAASTLSPQDVENVNFSVYSHIHLTGILPALTESTCTATLLMFERARAAGLTISFDPNLRPQLWPDEHTMRKTINDLAARADIVLPGTAEGKILMGSDDPAAICAFYQELGATTVITKCGAAGAYVADGAEHYKVTGFRVREVVDTVGAGDGFAAGILTGLMEGLPMRDAVRRAAAIGAIQVMSRGDNEGLPTPAELERFMKEADSTDE
>NZ_CP014239.1|WP_061945508.1|1212106_1212949_+|5-dehydro-4-deoxy-D-glucuronate-isomerase
MDVRYSAHPRDVKRYTTEELRREFLIQGLFQADQVSATYSHVDRMLVFGCMPISRHVSLDQGIDVWKNFGTAYILERREIGIFNVGQTGRITADGVSYTLHHRDCLYISMGTKDVNFESVNEAEPAKFYMVSAPAHKACKTTFLSMEQAKKVPAGALEFGNCRTINQYIHPDVLETCQLSMGLTVLDPGSVWNTMPAHTHERRMEVYFYFDFSPDDIVFHMMGEPTETRHLIMHCDEAVIGPSWSIHSGCGTSNYAFIWAMGGENKVFQDMDTVANRDLR
>NZ_CP014239.1|WP_061945510.1|1212962_1213748_+|gluconate-5-dehydrogenase
MTTQNRFALNGKVALVTGAAYGIGYAIAAAFARAGAKIAFNCRSKEHLQTALGTFRDDGIDALGYLCDVRDENSVAEMVQDIEKRCGVIDILVNNAGIIKRIPMCEMTAEEFREVVDIDLNAPFIVSKAVLPQMIEKGHGKIINICSMMSELGRETVSAYAAAKGGLKMLTRNIAAEYGRYNIQCNGLGPGYIATPQTAPLREHGHPFNDFILAKTPANRWGTPEDLAGPAIFLASDASNFVNGQILYADGGILAYIGKQP
>NZ_CP014239.1|WP_061945512.1|1213776_1214742_+|2-keto-3-deoxygluconate-transporter
MKIKQSIERIPGGLMLVPLFLGALCHTFAPWAGKYFGSFTNGLISGTVPILSVWFFCMGAGIDLRSTGTVLRKSGTIVVTKILVAWIIGMICVKFMPPGMIQTGFFAGLSTLAIVASMDMTNGGLYASIMQQYGTKEEAGAFVLTSIESGPLVTMFILGSTGAAYFEPRLFVGAVLPFVIGFILGNLDKELRTFFGSASMTMIPFFGFALGNTIDLAVIGQTGLLGILMGLSVIVVTGIPLFFADRWIAGGHGGAGLAASSTAGAAVTNPIIIAQMIPEFEPIAPAATALVATCVIVTALLVPVITASWCNYMKRKTEAQV
>NZ_CP014239.1|WP_061945514.1|1214962_1216324_+|sodium:alanine-symporter-family-protein
MESFLPVLNAVDTFLWGAPLIVLLVGTGIMLTLRLSLIQVRRLPRALALILRAKNRGEGDVSSFKALCVALAATIGTGNIVGVATAVKVGGPGAIFWMWMAAFFGMATKYAEGLLAVKYRTTDERGEIAGGPMYYIRHGMGEKYRPLAGFFACAAVLVAFFGIGTFPQVNAIVDSAELSFGVPRLVTDIALTVLIAAITIGGLRSIAEVASRIIPFMAVLYIVISLGIIAMHIDGIPAAIGLILDGAFTGTAAAGGFAGSTIMMAMQNGIARGVFSNESGLGSAPIAAAAAKTKEPAEQGLISMTGTFIDTIIICTMTGLVLVLTGAWQSDTAGAAMTGAAFTGAYGHIGGALLTISLALFAFTTILGWNYYGERAILYLAGVRAILPYRLVFIALIACGAFLKLEAIWVLADIVNGLMAIPNLIALIALSGIVVHETRRYLDKVKRSKRMRR
>NZ_CP014239.1|WP_061945516.1|1216694_1217966_-|sugar-phosphate-kinase
MSKMTLHEVVQKMLRLEGSAKATMVGIGPMSPTLIKATMLLAKQKDFPLMFIASRNQVDADELGGGYVCHWDQARFHKAIQETAKAVGYEGLYYLCRDHGGPWQRDNERNAHLPEDEAMRLGKQSYLVDLENGFDLLHIDPTKDPYVVGKVIDMDVNIRRTVELIDYVETERKKRNLPPVSYEVGTEETNGGLTSPENYEKFIEKLHAQLDAKGLPHPAFIVGNTGTLTRLTENVGHVDSTSCKELSAVAKKYGVGLKEHNGDYLDDATLLEHPALGVTAMNVAPEFGTVETQAYLKLIETEERLVKQGLIKEASGLGAALREESVQSGRWKKWMVDGKDQLLPEDIFKDEKLTQLIIEISGHYTFDLPRVKEEIARLYQNLAVSGIDGEKYVIYKIQASVDHYVACFNLTGLTSKLKESPIK

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Crispr_ID: NZ_CP014239_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014239_4

2037991-2038245

TypeIII

Consensus_repeat	Method
GCTGCACCACCAACAAAGCCGCGTGCGGCATTGAAAC	PILER-CR
ACAAAGCCGCGTGCGGCATTGAAAC	CRT

3 spacers

csm3gr7,csx19,csx10gr5,cas10,cas6,csx20,csx1

The CRISPR arrays of NZ_CP014239_4

>merge|NZ_CP014239|4|2037991-2038245|PILER-CR,CRT
GCTGCACCACCAACAAAGCCGCGTGCGGCATTGAAACTAGCCGTAAAGAGGGCGTGCCTCCCACCATGCAGGGCTGCACCACACACAAAGCCGCGTGCGGCATTGAAACTTCAGAATTGTTCTTCATAAAGAATCCCTCCTAAAAGCTGCACCACCAACAAAGCCGCGTGCGGCATTGAAACGAAACAAGTCCGGCTTTTGTCGCCATGTACATCTTGGCTGCACCACCCACAAAGCCGCGTGCCTACATTGATT

>NZ_CP014239|4|3|2037991-2038172|PILER-CR
GCTGCACCACCAACAAAGCCGCGTGCGGCATTGAAAC	TAGCCGTAAAGAGGGCGTGCCTCCCACCATGCAGG
GCTGCACCACACACAAAGCCGCGTGCGGCATTGAAAC	TTCAGAATTGTTCTTCATAAAGAATCCCTCCTAAAA
GCTGCACCACCAACAAAGCCGCGTGCGGCATTGAAAC

>NZ_CP014239|4|2|2038003-2038245|CRT
ACAAAGCCGCGTGCGGCATTGAAAC	TAGCCGTAAAGAGGGCGTGCCTCCCACCATGCAGGGCTGCACCACAC
ACAAAGCCGCGTGCGGCATTGAAAC	TTCAGAATTGTTCTTCATAAAGAATCCCTCCTAAAAGCTGCACCACCA
ACAAAGCCGCGTGCGGCATTGAAAC	GAAACAAGTCCGGCTTTTGTCGCCATGTACATCTTGGCTGCACCACCC
ACAAAGCCGCGTGCCTACATTGATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014239.1\|WP_061946593.1\|2039018_2039510_+\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674
NZ_CP014239.1\|WP_061946603.1\|2044555_2045491_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NZ_CP014239.1\|WP_061946587.1\|2033852_2035229_+\|CRISPR-associated-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274211
NZ_CP014239.1\|WP_061946597.1\|2040150_2040651_+\|DUF177-domain-containing-protein	unknown	unknown	gnl\|CDD\|376863
NZ_CP014239.1\|WP_061946585.1\|2029802_2031392_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|187810
NZ_CP014239.1\|WP_061946579.1\|2026730_2028467_+\|CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	gnl\|CDD\|187863
NZ_CP014239.1\|WP_009442436.1\|2043596_2044544_+\|enoyl-[acyl-carrier-protein]-reductase-FabK	unknown	unknown	gnl\|CDD\|132195
NZ_CP014239.1\|WP_061946581.1\|2028469_2028835_+\|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	unknown
NZ_CP014239.1\|WP_061946601.1\|2042592_2043597_+\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475
NZ_CP014239.1\|WP_061946583.1\|2028884_2029706_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl\|CDD\|273848
NZ_CP014239.1\|WP_061946599.1\|2041583_2042600_+\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
NZ_CP014239.1\|WP_009442443.1\|2039546_2040086_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP014239.1\|WP_061946993.1\|2031394_2032252_+\|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NZ_CP014239.1\|WP_061946990.1\|2032248_2033856_+\|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl\|CDD\|131722
NZ_CP014239.1\|WP_006306287.1\|2040666_2040846_+\|50S-ribosomal-protein-L32	unknown	unknown	gnl\|CDD\|237038
NZ_CP014239.1\|WP_009442439.1\|2041001_2041556_+\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
NZ_CP014239.1\|WP_061946577.1\|2024878_2026729_+\|hypothetical-protein	csx1	cd09732_csx1_CAS-III	gnl\|CDD\|378186
NZ_CP014239.1\|WP_061946591.1\|2035817_2037611_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
NZ_CP014239.1\|WP_061946589.1\|2035225_2035825_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl\|CDD\|274900
NZ_CP014239.1\|WP_061946592.1\|2038467_2039022_+\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl\|CDD\|223813

Protein	Function_ID	Function_description	E-value
NZ_CP014239.1\|WP_061946603.1\|2044555_2045491_+\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	3.01123e-127
NZ_CP014239.1\|WP_061946587.1\|2033852_2035229_+\|CRISPR-associated-protein	gnl\|CDD\|274211	TIGR02581, putative_CRISPR-associated_protein, CRISPR-associated RAMP protein, SSO1426 family. Members of this CRISPR-associated (cas) gene family are found in the RAMP-2 subtype of CRISPR/cas locus and designated TM1809 family.	3.06181e-17
NZ_CP014239.1\|WP_061946597.1\|2040150_2040651_+\|DUF177-domain-containing-protein	gnl\|CDD\|376863	pfam02620, DUF177, Uncharacterized ACR, COG1399. This family is nearly universally conserved in bacteria and plants except the Chlorophyceae algae. Thus far, mutantional analysis in bacteria have not established a function. In contrast, mutants have embryo lethal phenotypes in maize and Arabidopsis. In maize, the mutant embryos arrest at an early transition stage.It has been suggested that family members specifically affect 23S rRNA accumulation in plastids as well as bacteria.	4.57261e-21
NZ_CP014239.1\|WP_061946585.1\|2029802_2031392_+\|hypothetical-protein	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	9.71538e-07
NZ_CP014239.1\|WP_061946579.1\|2026730_2028467_+\|CRISPR-associated-protein	gnl\|CDD\|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	2.88375e-05
NZ_CP014239.1\|WP_009442436.1\|2043596_2044544_+\|enoyl-[acyl-carrier-protein]-reductase-FabK	gnl\|CDD\|132195	TIGR03151, enACPred_II, putative enoyl-[acyl-carrier-protein] reductase II. This oxidoreductase of the 2-nitropropane dioxygenase family (pfam03060) is commonly found in apparent operons with genes involved in fatty acid biosynthesis. Furthermore, this genomic context generally includes the fabG 3-oxoacyl-[ACP] reductase and lacks the fabI enoyl-[ACP] reductase.	7.34788e-167
NZ_CP014239.1\|WP_061946599.1\|2041583_2042600_+\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	3.19579e-174
NZ_CP014239.1\|WP_061946601.1\|2042592_2043597_+\|ketoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	0
NZ_CP014239.1\|WP_061946583.1\|2028884_2029706_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	4.21131e-09
NZ_CP014239.1\|WP_061946592.1\|2038467_2039022_+\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl\|CDD\|223813	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair].	4.89878e-61
NZ_CP014239.1\|WP_009442443.1\|2039546_2040086_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00756832
NZ_CP014239.1\|WP_061946993.1\|2031394_2032252_+\|CRISPR-associated-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.01318e-11
NZ_CP014239.1\|WP_061946593.1\|2039018_2039510_+\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	3.54574e-76
NZ_CP014239.1\|WP_006306287.1\|2040666_2040846_+\|50S-ribosomal-protein-L32	gnl\|CDD\|237038	PRK12286, rpmF, 50S ribosomal protein L32; Reviewed.	6.5601e-28
NZ_CP014239.1\|WP_009442439.1\|2041001_2041556_+\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	1.34456e-81
NZ_CP014239.1\|WP_061946577.1\|2024878_2026729_+\|hypothetical-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	1.05084e-06
NZ_CP014239.1\|WP_061946591.1\|2035817_2037611_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	3.92811e-91
NZ_CP014239.1\|WP_061946589.1\|2035225_2035825_+\|TIGR03984-family-CRISPR-associated-protein	gnl\|CDD\|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	4.92936e-29
NZ_CP014239.1\|WP_061946990.1\|2032248_2033856_+\|hypothetical-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	3.46853e-08

>NZ_CP014239.1|WP_061946591.1|2035817_2037611_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MAKDYDTATAPYNFVSLPQGVLTSPIEGDAMSDAERVENYRAHVLAKGRLSGRIDLEIKTLTPVFIGTGVDAGDAVENFFAPTGIPILPGSSLRGMIKNLFKIVTCSAMRAGEDYHDQVLYFRTLADREKNMQRLYTTEMATTVRKGTNTISETKAEAGYLVQQTGDDGYYICPAEFDIMTYGVGRQPENEVRWGEPGSGRADCHTGRMHKKGTYTRHRDPDWTQRIPVSNHVVQAYREDSSRKGVELLDKEKGHFCAKKGDAAASFTGWDDIRFVAPCFYKTDAQGEIAHFGFGRFYRIAYHMSIGDHVLRMESERIDYTDALFGRREERECARVGREQTNRRSGCKELWASRLAFADAVPKETPRTEAPHFPQILSAPKPTAVQLYLEQKNGANRLAHWDSAGVPIRGYKLYWHQKNGTAWMNREQDEPNTQTQRKIQPVAAGNTFYGSIRFERLSEDELGALLKVLCLCDGCLLCKIGKGKPIGLGSIEITPRLFLTDTEDSYHSAFDGEGGWNTAERETEMNAYIQVFERELDRLGKDVRARYDKAQKELVHLLRWDHTKDPKWEEKIAQMTIGQGDRRFQGRAILPTALDVK
>NZ_CP014239.1|WP_061946589.1|2035225_2035825_+|TIGR03984-family-CRISPR-associated-protein
MSKEKKQKMRCICAGKSAVETVDIPASAEELSRELTRRNVQKATAILWQVNKIHCGTWQQGTFSFPDEAPLNTKLLIELRIFNETSELHLQRKNDRLIGRFRTDGEGEAAEYVDTLARFWGSRSDATREEEQHSAWMTLRDPERKLKLTLPKIEDSAENPVYVGLVTRSYIGIHTTGQAGYVDHRYCRIAAADMEESNG
>NZ_CP014239.1|WP_061946587.1|2033852_2035229_+|CRISPR-associated-protein
MNTNVNPAQILGRITVRGRLHLAAPLLIGEGESGEDRNDRDIHVLRSKDGVPFIPGTSLAGALRSFIEADTPCAADILFGTMHRTGGESVCDERQSAVSLYDVELNDAVIGSRDGVHIDDVTGTAIDAHKYDYEIVESGAGGPFYAEIFLRRVHQKDEHMLKETLLRLSELLRGGFHVGALTTKGFGRMQLRDMVVDCYDFRRTEDAIAWLSPQRGNAAWHMAYDDTAQAEPPPAKGDFVITADFALTGALIVRDSVDPLAADGEKSPAARMKTNAAGQNIIPGTTLKGVLRHRAAYILHALGKEQTQAEAFIDRLMGTTAARGRFIVEEAVVDAEMHTQTRSRIDRFTGGTIPSALFSTAPVWRKKDEGRSVTLRFGVRQASEQEAGLCVLLLKDLWLGRAAIGGEKSIGRGTLEGLHAVIHYHGRCYELAQGQNFAADTVQSLQGYVTALCEEDAT
>NZ_CP014239.1|WP_061946990.1|2032248_2033856_+|hypothetical-protein
MMQMMKVRIRTKAPMILSAPGHTSVMTATQDSFSGSVLRGIFAARFIKAAALGNAAHENDDFMRLFYGGLRFVNAYPVEPLTQTRAIPLPLSVQRSKDGSSICDLMYGEAPRDGGFKSMRGFAAVCDKGLHPVAVQKEIRLHISRSDLNGGSGKERLAGRSMDGGVYNYEAIAQGQSFEGLICGAEEELRLLCGTIGTETFSCCAGRSKYTQYGQCEITVMPAEDISLPPIPTEERFCLRCETPFLPHRAVLGDARSMLDEVVDALNAGTDGGFLLAEEQRSIYAQAEDIDNFVGVWGMRRPRETALSAGTVFAVRKTGGWQPCDMEAVNAILCSGVGRRTEEGFGQLRIWDGRGLCCIAQDPPTPEARELCTESRRIAEQIILAHIIEQIRVLAAEDAGRARRTFPPDASHAFARLDSALGIRPQGACERIRQIVLDTKKEMPLGKMLENVKVEGRPLRSYLGEIIHEEMPYAARERQNVTAEQDLIDAGKEIGVWGGTAALLKQEEVFYAYWHTFFRFARKTAGKPEKGGESA
>NZ_CP014239.1|WP_061946993.1|2031394_2032252_+|CRISPR-associated-protein
MAKNRNKDGKTGQKKIKYGKKEPVVRQSTREPDEPQIRQADTVDPFAMMQTQPAGLGDIDPAAPIRIHIRTFSPLHLGTGYADIHVDADVVQDDVGLPYFPAKRLKGLLYESGCEVAEMAETAELDLFDRAALDTLFQRGRMGQVQLILHNLYMEQYEEIHADLKHLEEKYPSIFRPEDVLGVYANLRWQTRINRETGIAEQTTLHNMRVIEKGAAFSGEIRLVDAGIKHLCILALAVRNLSQCGGKRTRGFGRIGCTLRQNGKDIVPALITKAIGRQGRKGGRR
>NZ_CP014239.1|WP_061946585.1|2029802_2031392_+|hypothetical-protein
MQYKAILFDTRSIQKYIFSSNQLKTNIGASYLVEAVFEEILLPAVREILGADTLDDMSWKRPEDTDWSSMTAAARVGYIGGGKALLLFAEHVDDDILSAVIAAFTKKLLIHAPGLHTGAATGTLELAADGRYIGAERLNPLFDRLKEGQNTVFPAVNVPYTGLTLACSETGETANAWVDGRFCSWEVAAKLHPTFPSGSGEADVQQALMDKLMTAFTPEEQEHFIGRYDFPVEFARLGQKTPKNDIAVVHIDGNNMGRKFQGCETLTAYIRRSRGIRHDTLAVFAALVKHIVEHIDRYKDSLDLRDEHGLCTLPVRPIVLGGDDMTFVCAGKAAVEFSAFLMQHLMEKNIASCAGITIMNTSYPFFRAYEMAEELCGAAKNEMRALERAAGHEVDSCWLDFAILHGEQPPTLEQFRAREYRGARGDLHFGPYRVDTDGAGATDERHITALLAGVRGLRRLPRNKVKELRRVLAYGKHEQQQFMTQLGHLNLQLPDVPAWRAYAENLWEQERTPYMDAIELMDYVMDGEV
>NZ_CP014239.1|WP_061946583.1|2028884_2029706_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MLGILVLRLRTERGGHYSMFPGKLLHGALFRCIAAYDATFAAELHARKMKPFTIGFFRRTGKNNAAVLRAQELNEPHYAEGEELLLRLTALDENVLAALLRIPLGTVLAVGQLSFIVEEILADGRENTGVIAEEELIAAALSAEDAQKIRISFRSPTVFRVDKDDCAVPRPALIFASLADKWTWQELPFAVDKDIVRAIAAKLIPLDWLGAGVRIRQSERKTMPGFTGTFAFSIGRLSPEEREIILLLAQFAPFCGVGRLTAQGFGETIVALG
>NZ_CP014239.1|WP_061946581.1|2028469_2028835_+|hypothetical-protein
MTEFINHTNHPSSRWEEGQRQAAEAYGIIVDLPFPRIPADWDAQAVHRLAEENAQEILARKPMAVLVQGEFTYTFALVSLLKAAGIAVLSACSERLVNERVDENGETIRESRFVFRRFRAY
>NZ_CP014239.1|WP_061946579.1|2026730_2028467_+|CRISPR-associated-protein
MRTNIMLCFLSDVKLVRETGAISVADYQNIGEKKKCHTTNESAVRYLLSGAHEPADRLSRLFLVRTNKVAGAIQGYNATHDWEQTHYDYFLHRISDIVPHAEQIAEAIDFDENEPIEENTNVLIDVASHVRRYAKAVRKDHPDTEIILHVDVTGGLRNASMILVALMRLLQYENIRIGKVLYSDYNKKRVEEVNPLYSFFDLVAGAEEFVRHGEVTVMNRFFEQREKSQALRALLASMRKFAEELKLCHYGDLRDAIVELQRSITAFSSAATGNATAEAKQSDELMRQMLGRIEEDYAKILKEELNDIALIRWCIAHDLLQQAMTLVTERIPEALVDSGFLSLSSEEVQALFECKLEEDSMHRNRGVFLVTEFKYKNMKNFQKARNEWREKRQRFFKEFRQEVTEDKINEFVDGRLSDRFEVRLKDAETLRAFLLWLNRMRSPEKCSLQHTEHGRTYLEQIKPIYIDATKGDWDALLANKDNFVVAKLIRILGSQDSKCPFLDIEWKPGACRLYEAGIEPKDKNLAEDILDKYFVIKDERNHTNHARAEKGRMAVDSLKNSMEQILKDTEIACRMAKE
>NZ_CP014239.1|WP_061946577.1|2024878_2026729_+|hypothetical-protein
MNQNIAINFFSPVRCKTDPDTGRRICIVTEGNFILEVGSEPFPGFQTNEAPLADVVDLLAQKGERLHRVYCLVTPQCLSAEMGGEDRGLVVEEHGERSKYPSQFEFWCSRMKRLRPALVETDFIPILLHYHEDTLIEDIESQVASLTERIKADAGGFAEWHACHIYADITGGARYVTMMMTSVMQFLQYDGMRVEKMIYADFKTLSLENRIFDVHGTLDVYKLVAGADAFVSYGISRTIEEYFDYDAESGTSGKPISDALKGVLRAMHTFSDAIQICQTGNIPPALSALSTAITIFLDVPEEDRTVDDRMFMQLIDTITEGYGELLGETEDEAERYVPIIRWCIEKGLLQQAMTLATEWLPVCFVRQGIVYPVSAYMPCAERSVDRMHPGWMQNFIINSTQYWNAIQTMCVDTYKPILTDALEHGIVPERAPSLVLSYCKLGQTFQHLRENPAEIRTLPEDVLWLYELVCTQIEKEKDGQRWTVPKLLQDGAAWARIKSKLLNKILEKKNNPLVFRLLGIQKCKFPSGSSDDLDRRWAAWEDTWTKMLETMGIVQTDCGRKHMMSCLRAYFYLREQRNQVNHATAENTLGRREIVGLLDNVLAELSAAASNSQEER
>NZ_CP014239.1|WP_061946592.1|2038467_2039022_+|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MRIITGSARGTRLKSPAGDGTRPTADRTREALFSMLGSRVVDARVLDLFAGTGALALEALSRGAASAVLVDRTTQAILAENATRTKLTGRVEIRRGDVYAAAAELAREGRTFDLIFADPPYAHGDNDRVLEAAARGALLAAGGLLVLEQGAGEEIVLQAGALRLMRERRYGAARICFYAEEEQG
>NZ_CP014239.1|WP_061946593.1|2039018_2039510_+|pantetheine-phosphate-adenylyltransferase
MRRAVFAGSFDPVTTGHIDIVERAASMFDELIVCIFHNVAKEGCFPLEQRVEFLRTATAHVPNVRVDVSSGLLTDYMRRERAHVVVRGLRSVKDFEYEENHAAMVRHLMPESDTIFLLTRPDLTFISSSGVRELIRFRGPVQGIVPPPVEQAILKLYEKPRRG
>NZ_CP014239.1|WP_009442443.1|2039546_2040086_+|hypothetical-protein
MAVTDTLKKLEDLVADASHLPFSDKALVNDDEIVHLVEELRMDLPKELNRAAEIMQEQEGIIARANEQAKNIVSAAEARANQLLEESEIVIQAKERARAIMQQSQDQARELMEQSQANATRLQSDADAYANQVFEQLIAHVGSTFKGVQQAEAGLNQALNVLRTAKAQMNAPQGDGQEL
>NZ_CP014239.1|WP_061946597.1|2040150_2040651_+|DUF177-domain-containing-protein
MMKLDVAALASAPGESREFTFSVTPESLDLGDSTTAYRGAVHVEGTVMDTGTSFRIVGTVRAVRAFVCDRCLAEGERENTYDFSEDYAKTPGEVDETEGCDGETIVLDPLVRDTLLVAEPLRELCKSDCKGLCPVCGQNLNEGTCTCNTFVPDPRLAALESLLKND
>NZ_CP014239.1|WP_006306287.1|2040666_2040846_+|50S-ribosomal-protein-L32
MAVPKRKTSKARRDRRRANWKLEAPHYVSCPQCHEPKLPHHVCMECGYYDGKPVAEAAE
>NZ_CP014239.1|WP_009442439.1|2041001_2041556_+|transcription-factor-FapR
MTEKKRRRQESLVLAVRKEPFLTDEALARRLSVSVQTVRLDRTELGIPELRARVRTLAENAREKVRAIPHAEVVGDLLSLELGVRGTSALKVTDDHLFADSEIARGTALFSQANSLALAIVDAPLAVTGVANVKYKTPIYKGDTVIAQAEIVKIRGNKIFVWVKTYRDGREVFRAKFIVVSLGK
>NZ_CP014239.1|WP_061946599.1|2041583_2042600_+|phosphate-acyltransferase-PlsX
MRIAVDAMGGDFAPKEIVRGAIDAAKKYDCEIVLVGDEAKIRAELGGADTDALHISIVHAADVIGMDEAPAEAVRSKKDASIVVATCMVKDGECDAVFSAGSTGAAVTAAQLILHRIRGVSRPTIATPMPTPDGVTLMLDSGANVDSKPEHLVQSAVMGSLYAQYVFGVERPRVGLLNIGEEETKGNEQAKETYPLLKTDPNIYFCGNAEGRDVPKGNFDVVVCDGFVGNVVLKFAEGLAKTILGLIREEIRGAGLMAKLGALLLMPTLRHLGKRLDVREYGGAPLLGVNGCCVIGHGSSDAKSIASAIGVAVSYVNGKVLDQIRDALAKDEEETGRV
>NZ_CP014239.1|WP_061946601.1|2042592_2043597_+|ketoacyl-ACP-synthase-III
MSKISAGILGTGYYVPKRVLTNFDLEKMVQTNDAWIVERTGIHERRIAAPDEPVSALAQRAAEMALADAGVAAADLDLIIMATLTSDRIIPATACVLQDRLGAKHAAAFDLSAACSGFVYAASIAAQFIESGVYRHVLVIGGETLSKVIDWTDRNTCILFGDGAGAAVFGAVEDGYGMRAFDLGSDGSGADALDIPSSGSLCPVTPETIEQRLNFVHMDGKAVFRFAAKVMGKTVETSLHRAGMEREELDYLVPHQANIRIIQAAAKRLAMPMEKVIINIHHYGNMSAASIPVALAEAAHAHRFKKGDNIALAGFGAGLTWASCIMKWAKEENG
>NZ_CP014239.1|WP_009442436.1|2043596_2044544_+|enoyl-[acyl-carrier-protein]-reductase-FabK
MFEHNPICQMLGIKYPIFQGGMAWIGTAELASAVSNAGGLGLIGAGHMPPDALRAEIQKVKGWTDKPFGVNVMLMSPFVKEVMQVVLEERVPVITTGAGNPGEYVPALKEIGSKVIPVVASVALARRLERTGVDAVIAEGTESGGHIGEITTMALLPQVVDALHVPVIGAGGIGDARGMAAAFALGAQAIQMGSRFVLSTECIAHPNYKNAVLKAKDRSTVVTGRSLGHPARVLHNKLSRKYEEMEAAGASHEELEQLGVGSLHRATHEGDVENGSVMIGEISGMLSDIKPVKEIIEDIVRDLPGAMDAARKVCD
>NZ_CP014239.1|WP_061946603.1|2044555_2045491_+|ACP-S-malonyltransferase
MGKLAFLFPGQGAQVVGMGRDFYDAYDLAKERFAEADEALGYSISKLCFEGPADQLQLTENTQPAILTVSVIAAQLLQERGVSPAIAGGHSLGEYAALVLAGALSFRDAVVLVHKRGAYMQEAVPVGEGAMAAIIGLDDATIIDACAAASAQGAVQAVNFNCPGQTVIAGAEKGVSAAVELLKEKGAKKAVILPVSAPFHSTLMAPAAKKLAAELDKVALHDAAFPIVSNYTGGLQQTAAEIKENLVAQADHPVRWIACVATMRDFGADTYIECGPGKTLAGFNKRIDKTLTSLNVEDEASLQKTLDTLNK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP019840	Enterobacter roggenkampii strain R11 plasmid pASM1, complete sequence	84639-84677	9	0.769
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP022149	Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_1, complete sequence	64657-64695	9	0.769
NZ_CP014239_4	4.2\|2038100\|36\|NZ_CP014239\|PILER-CR	2038100-2038135	36	NC_005893	Lactobacillus phage phiAT3, complete genome	24445-24480	9	0.75
NZ_CP014239_4	4.2\|2038100\|36\|NZ_CP014239\|PILER-CR	2038100-2038135	36	AY605066	Bacteriophage phi AT3, complete sequence	24445-24480	9	0.75
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_KX786187	Enterobacter cloacae strain N14-0444 plasmid pIMI-6, complete sequence	127766-127804	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_KX858825	Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence	57315-57353	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_KX858825	Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence	62570-62608	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_KT225520	Raoultella ornithinolytica strain RJ46C plasmid pRJ46C, complete sequence	83327-83365	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_LS999207	Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence	4619-4657	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_LS999207	Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence	10819-10857	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_LS999207	Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence	14069-14107	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_LS999207	Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence	145609-145647	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP039454	Enterobacter bugandensis strain 220 plasmid pSurvcare220, complete sequence	86724-86762	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NC_014107	Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_A, complete sequence	57113-57151	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP033467	Enterobacter cloacae strain E3442 plasmid p3442-FRI-1, complete sequence	39244-39282	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP034768	Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence	24049-24087	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP034768	Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence	29741-29779	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP034768	Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence	34468-34506	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP031569	Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence	16834-16872	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP031569	Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence	37389-37427	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP043854	Enterobacter hormaechei strain EB_P6_L3_02.19 plasmid unnamed1, complete sequence	110497-110535	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP043854	Enterobacter hormaechei strain EB_P6_L3_02.19 plasmid unnamed1, complete sequence	121541-121579	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP012169	Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-210.894kb, complete sequence	80679-80717	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP027145	Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed2, complete sequence	77966-78004	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP027145	Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed2, complete sequence	83666-83704	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP027145	Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed2, complete sequence	86686-86724	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP033799	Enterobacter roggenkampii strain FDAARGOS_523 plasmid unnamed3, complete sequence	68468-68506	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP033799	Enterobacter roggenkampii strain FDAARGOS_523 plasmid unnamed3, complete sequence	87304-87342	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP033799	Enterobacter roggenkampii strain FDAARGOS_523 plasmid unnamed3, complete sequence	90330-90368	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP043512	Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed1, complete sequence	137180-137218	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP043512	Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed1, complete sequence	140477-140515	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_AP019534	Enterobacter asburiae strain MRY18-106 plasmid pMRY18-106EAS_1, complete sequence	24869-24907	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_AP019534	Enterobacter asburiae strain MRY18-106 plasmid pMRY18-106EAS_1, complete sequence	30572-30610	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_LT991956	Enterobacter hormaechei subsp. steigerwaltii isolate C309 plasmid pC309-p2	76707-76745	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP021777	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0053 plasmid unitig_2, complete sequence	23265-23303	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP045770	Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence	167-205	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP045770	Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence	3137-3175	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP045770	Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence	93031-93069	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP045770	Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence	98727-98765	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_AP019633	Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence	26544-26582	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_AP019633	Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence	32240-32278	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_AP019633	Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence	35271-35309	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_AP019633	Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence	36544-36582	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	KT780723	Uncultured bacterium plasmid pGA45, complete sequence	37921-37959	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_AP019635	Enterobacter sp. 18A13 plasmid pECC18A13-1, complete sequence	54316-54354	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_AP019631	Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence	20807-20845	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP020054	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0065 plasmid unitig_1, complete sequence	48580-48618	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP020054	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0065 plasmid unitig_1, complete sequence	67416-67454	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	MK471334	Enterobacter cloacae plasmid pNRZ-28021, complete sequence	46077-46115	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_KX912253	Enterobacter asburiae strain H162620587 plasmid pJF-587, complete sequence	79304-79342	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_KX912253	Enterobacter asburiae strain H162620587 plasmid pJF-587, complete sequence	85296-85334	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP035636	Enterobacter cloacae strain EN3600 plasmid unnamed4, complete sequence	83836-83874	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP050011	Citrobacter sp. Y3 plasmid unnamed2, complete sequence	5075-5113	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP050011	Citrobacter sp. Y3 plasmid unnamed2, complete sequence	8329-8367	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP050011	Citrobacter sp. Y3 plasmid unnamed2, complete sequence	19147-19185	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP017187	Enterobacter hormaechei subsp. hoffmannii strain DSM 14563 plasmid pDSMZ14563, complete sequence	114515-114553	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP017187	Enterobacter hormaechei subsp. hoffmannii strain DSM 14563 plasmid pDSMZ14563, complete sequence	117765-117803	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP017187	Enterobacter hormaechei subsp. hoffmannii strain DSM 14563 plasmid pDSMZ14563, complete sequence	123965-124003	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP017991	Enterobacter cloacae complex sp. ECNIH7 plasmid pENT-1ac, complete sequence	123086-123124	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	CP032294	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0073 plasmid unnamed3, complete sequence	77464-77502	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	CP032294	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0073 plasmid unnamed3, complete sequence	80490-80528	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	CP032294	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0073 plasmid unnamed3, complete sequence	99325-99363	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP019890	Enterobacter hormaechei strain FRM plasmid unnamed1, complete sequence	72604-72642	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP019890	Enterobacter hormaechei strain FRM plasmid unnamed1, complete sequence	75807-75845	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP026851	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0072 plasmid unnamed1	56505-56543	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP022534	Enterobacter hormaechei strain MS7884A plasmid pMS7884B, complete sequence	102125-102163	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP022534	Enterobacter hormaechei strain MS7884A plasmid pMS7884B, complete sequence	105150-105188	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP022534	Enterobacter hormaechei strain MS7884A plasmid pMS7884B, complete sequence	123676-123714	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP029719	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence	110699-110737	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP029719	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence	131255-131293	10	0.744
NZ_CP014239_1	1.5\|1018665\|39\|NZ_CP014239\|CRISPRCasFinder,CRT,PILER-CR	1018665-1018703	39	NZ_CP034768	Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence	33046-33084	11	0.718

1. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019840 (Enterobacter roggenkampii strain R11 plasmid pASM1, complete sequence) position: , mismatch: 9, identity: 0.769

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
tgccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
**. .***************** ****.*****.  .**

2. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022149 (Enterobacter roggenkampii strain 704SK10 plasmid p704SK10_1, complete sequence) position: , mismatch: 9, identity: 0.769

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
tgccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
**. .***************** ****.*****.  .**

3. spacer 4.2|2038100|36|NZ_CP014239|PILER-CR matches to NC_005893 (Lactobacillus phage phiAT3, complete genome) position: , mismatch: 9, identity: 0.75

--ttcagaattgttcttcataaagaatccctcctaaaa	CRISPR spacer
gatcttgagc--ttcttcataatgaatccctccaaaaa	Protospacer
  *.. **..  ********** ********** ****

4. spacer 4.2|2038100|36|NZ_CP014239|PILER-CR matches to AY605066 (Bacteriophage phi AT3, complete sequence) position: , mismatch: 9, identity: 0.75

--ttcagaattgttcttcataaagaatccctcctaaaa	CRISPR spacer
gatcttgagc--ttcttcataatgaatccctccaaaaa	Protospacer
  *.. **..  ********** ********** ****

5. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX786187 (Enterobacter cloacae strain N14-0444 plasmid pIMI-6, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

6. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX858825 (Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

7. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX858825 (Enterobacter cloacae strain N13-1531 plasmid pIMI-5, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

8. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT225520 (Raoultella ornithinolytica strain RJ46C plasmid pRJ46C, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

9. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LS999207 (Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

10. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LS999207 (Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

11. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LS999207 (Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

12. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LS999207 (Enterobacter cloacae isolate EC-TO80 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

13. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039454 (Enterobacter bugandensis strain 220 plasmid pSurvcare220, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

14. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NC_014107 (Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_A, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

15. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033467 (Enterobacter cloacae strain E3442 plasmid p3442-FRI-1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

16. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034768 (Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

17. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034768 (Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

18. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034768 (Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

19. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031569 (Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

20. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031569 (Enterobacter hormaechei strain 2013_1a plasmid pIncFIB-1301491, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

21. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043854 (Enterobacter hormaechei strain EB_P6_L3_02.19 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

22. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043854 (Enterobacter hormaechei strain EB_P6_L3_02.19 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

23. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012169 (Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-210.894kb, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

24. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027145 (Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

25. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027145 (Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

26. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027145 (Enterobacter hormaechei subsp. hoffmannii strain AR_0365 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

27. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033799 (Enterobacter roggenkampii strain FDAARGOS_523 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

28. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033799 (Enterobacter roggenkampii strain FDAARGOS_523 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

29. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033799 (Enterobacter roggenkampii strain FDAARGOS_523 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

30. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043512 (Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

31. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043512 (Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

32. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019534 (Enterobacter asburiae strain MRY18-106 plasmid pMRY18-106EAS_1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

33. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019534 (Enterobacter asburiae strain MRY18-106 plasmid pMRY18-106EAS_1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

34. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT991956 (Enterobacter hormaechei subsp. steigerwaltii isolate C309 plasmid pC309-p2) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

35. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021777 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0053 plasmid unitig_2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

36. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045770 (Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

37. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045770 (Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

38. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045770 (Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

39. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045770 (Enterobacter cancerogenus strain MiY-F plasmid pCFSAN086183, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

40. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019633 (Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

41. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019633 (Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

42. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019633 (Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

43. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019633 (Enterobacter asburiae strain 1808-013 plasmid pEAS1808-013-1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

44. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to KT780723 (Uncultured bacterium plasmid pGA45, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

45. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019635 (Enterobacter sp. 18A13 plasmid pECC18A13-1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

46. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019631 (Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

47. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020054 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0065 plasmid unitig_1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

48. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020054 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0065 plasmid unitig_1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

49. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to MK471334 (Enterobacter cloacae plasmid pNRZ-28021, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

50. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX912253 (Enterobacter asburiae strain H162620587 plasmid pJF-587, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

51. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX912253 (Enterobacter asburiae strain H162620587 plasmid pJF-587, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

52. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035636 (Enterobacter cloacae strain EN3600 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

53. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050011 (Citrobacter sp. Y3 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

54. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050011 (Citrobacter sp. Y3 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

55. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050011 (Citrobacter sp. Y3 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

56. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017187 (Enterobacter hormaechei subsp. hoffmannii strain DSM 14563 plasmid pDSMZ14563, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

57. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017187 (Enterobacter hormaechei subsp. hoffmannii strain DSM 14563 plasmid pDSMZ14563, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

58. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017187 (Enterobacter hormaechei subsp. hoffmannii strain DSM 14563 plasmid pDSMZ14563, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

59. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017991 (Enterobacter cloacae complex sp. ECNIH7 plasmid pENT-1ac, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
cgccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
.*. .***************** ****.*****.  .**

60. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to CP032294 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0073 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

61. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to CP032294 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0073 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

62. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to CP032294 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0073 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

63. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019890 (Enterobacter hormaechei strain FRM plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

64. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019890 (Enterobacter hormaechei strain FRM plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

65. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026851 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0072 plasmid unnamed1) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

66. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022534 (Enterobacter hormaechei strain MS7884A plasmid pMS7884B, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

67. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022534 (Enterobacter hormaechei strain MS7884A plasmid pMS7884B, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

68. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022534 (Enterobacter hormaechei strain MS7884A plasmid pMS7884B, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

69. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029719 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

70. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029719 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0154 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.744

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgga	Protospacer
 *. .***************** ****.*****.  .**

71. spacer 1.5|1018665|39|NZ_CP014239|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034768 (Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence) position: , mismatch: 11, identity: 0.718

tgtaagcgcggtgaaggcgttcaggacagcacgaaaaga	CRISPR spacer
agccggcgcggtgaaggcgttccggacggcacggccgaa	Protospacer
 *. .***************** ****.*****.  ..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

23100 : 122651

Streptococcus_phage(13.51%)

protease,integrase,transposase,tRNA,tail,head,terminase,capsid,holin,portal

attL 65476:65494|attR 123167:123185

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006689390.1\|23100_24462_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_061943330.1\|24415_25078_-	bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase	NA	NA	NA	NA
WP_061943333.1\|25218_25980_-	5'/3'-nucleotidase SurE	NA	NA	NA	NA
WP_009441983.1\|26271_27222_-	malate dehydrogenase	NA	NA	NA	NA
WP_157064386.1\|27418_27580_-	hypothetical protein	NA	NA	NA	NA
WP_061943336.1\|28028_29534_-\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	1.6e-92	40.7
WP_006689565.1\|29545_30016_-	transcription elongation factor GreA	NA	NA	NA	NA
WP_061943340.1\|30029_30326_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_061943343.1\|30322_30931_-	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	1.2e-27	52.3
WP_083501132.1\|30954_31677_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_061943349.1\|31677_32598_-	YitT family protein	M1Q1P6	Streptococcus_phage	7.3e-40	32.7
WP_083501133.1\|32594_33257_-	hypothetical protein	NA	NA	NA	NA
WP_061943352.1\|33282_34515_-	aminopeptidase	NA	NA	NA	NA
WP_083501134.1\|34516_34963_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_061943355.1\|35039_36323_-	M18 family aminopeptidase	NA	NA	NA	NA
WP_061943358.1\|36585_37656_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.7e-67	40.8
WP_009442474.1\|37781_38243_-	nucleoside deaminase	S4VYT2	Pandoravirus	7.7e-06	40.9
WP_009442475.1\|38232_38511_-	hypothetical protein	NA	NA	NA	NA
WP_061943361.1\|39842_40802_+	ATP-binding protein	A0A2K9R7H3	Dishui_lake_phycodnavirus	5.0e-15	28.7
WP_071884664.1\|43371_43605_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_157064450.1\|43588_43675_+	hypothetical protein	NA	NA	NA	NA
WP_061943364.1\|43922_46811_+	ATP-dependent helicase	A0A068EQC7	Bacillus_phage	3.6e-32	27.5
WP_061943367.1\|46825_48688_+	site-specific DNA-methyltransferase	S0A0D5	Cellulophaga_phage	1.9e-39	39.1
WP_061943370.1\|48688_51316_+	type III restriction endonuclease	NA	NA	NA	NA
WP_061943373.1\|51691_52606_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_157064387.1\|52651_53167_-	O-acetyl-ADP-ribose deacetylase	A0A140GBC4	Giant_seaperch_iridovirus	1.4e-40	56.0
WP_061943379.1\|53359_53707_-	histidine triad nucleotide-binding protein	NA	NA	NA	NA
WP_061943381.1\|53773_57568_-	helicase-exonuclease AddAB subunit AddA	S5M596	Bacillus_phage	3.1e-15	23.6
WP_061943384.1\|57521_61118_-	ATP-dependent deoxyribonuclease subunit B	NA	NA	NA	NA
WP_061943387.1\|61114_64195_-	SMC family ATPase	A0A192YBB5	Morganella_phage	2.1e-06	26.8
WP_061943390.1\|64191_65337_-	exonuclease SbcCD subunit D	NA	NA	NA	NA
WP_061943393.1\|65406_67440_-	NAD-dependent DNA ligase LigA	A0A0A8J9A9	Ralstonia_phage	3.3e-85	33.8
65476:65494	attL	NA	NA	NA	NA
WP_061943397.1\|67447_69688_-	DNA helicase PcrA	A7KV33	Bacillus_phage	2.7e-136	42.5
WP_039980876.1\|69767_71414_-	putative manganese-dependent inorganic diphosphatase	NA	NA	NA	NA
WP_061943400.1\|71543_71900_-	YraN family protein	NA	NA	NA	NA
WP_006689416.1\|71896_72208_-	flagellar biosynthesis protein FlhB	NA	NA	NA	NA
WP_061943403.1\|72304_74458_-	hypothetical protein	NA	NA	NA	NA
WP_061943406.1\|74447_75227_-	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	2.5e-25	40.2
WP_061943408.1\|75253_76144_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_061943412.1\|76349_76970_-	hypothetical protein	NA	NA	NA	NA
WP_061943415.1\|77014_77551_-	N-acetylmuramoyl-L-alanine amidase	A0A240EWQ9	Vibrio_phage	2.2e-20	38.5
WP_061946896.1\|77547_77973_-\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	7.5e-32	58.5
WP_061943418.1\|77972_79076_-	hypothetical protein	NA	NA	NA	NA
WP_061943421.1\|79080_79302_-	hypothetical protein	NA	NA	NA	NA
WP_061943424.1\|79298_80993_-	hypothetical protein	NA	NA	NA	NA
WP_061943427.1\|80989_81910_-	hypothetical protein	NA	NA	NA	NA
WP_061943430.1\|81920_82334_-	hypothetical protein	NA	NA	NA	NA
WP_083501135.1\|82336_82690_-	phosphoribosylformylglycinamidine cyclo-ligase	NA	NA	NA	NA
WP_061943433.1\|82649_85202_-	hypothetical protein	NA	NA	NA	NA
WP_061943436.1\|85388_85703_-	hypothetical protein	NA	NA	NA	NA
WP_061943439.1\|85714_86314_-\|tail	phage tail protein	NA	NA	NA	NA
WP_061943442.1\|86315_86678_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_061943444.1\|86674_87073_-	histone H1	NA	NA	NA	NA
WP_061943447.1\|87065_87392_-\|head	phage head closure protein	NA	NA	NA	NA
WP_061943449.1\|87404_87680_-\|head,tail	phage gp6-like head-tail connector protein	A0A1B0RXK2	Streptococcus_phage	1.2e-14	49.5
WP_061943451.1\|87708_88881_-\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	4.6e-95	47.3
WP_061943454.1\|88894_89590_-\|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	8.8e-70	60.5
WP_061943457.1\|89579_90836_-\|portal	phage portal protein	Q6DMU2	Streptococcus_phage	1.6e-175	74.0
WP_061943460.1\|90850_92452_-\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	2.8e-260	80.4
WP_061943463.1\|92464_93031_-\|terminase	terminase	A0A2K5B277	Erysipelothrix_phage	1.7e-47	51.9
WP_061943465.1\|93142_93499_-	HNH endonuclease	NA	NA	NA	NA
WP_061943468.1\|93608_94037_-	hypothetical protein	NA	NA	NA	NA
WP_061943470.1\|94109_94481_-	hypothetical protein	NA	NA	NA	NA
WP_061943473.1\|94877_95306_-	hypothetical protein	NA	NA	NA	NA
WP_061943476.1\|95382_95886_-	class I SAM-dependent methyltransferase	A0A2H4PBJ4	Lactobacillus_phage	2.6e-47	55.9
WP_061943478.1\|96312_96759_-	hypothetical protein	NA	NA	NA	NA
WP_061943481.1\|97096_100042_-	DUF927 domain-containing protein	I3VYX9	Thermoanaerobacterium_phage	6.3e-85	36.3
WP_061943484.1\|100062_100455_-	VRR-NUC domain-containing protein	V5YTP9	Pseudomonas_phage	8.5e-22	45.3
WP_061943487.1\|100458_101823_-	DEAD/DEAH box helicase	V5YTP6	Pseudomonas_phage	4.2e-84	40.2
WP_061943489.1\|101829_102375_-	single-stranded DNA-binding protein	Q8SBL5	Clostridium_phage	2.3e-09	36.9
WP_061943492.1\|102390_103071_-	single-stranded DNA-binding protein	A0A0A7RVW0	Clostridium_phage	3.8e-33	52.7
WP_061943494.1\|103067_103571_-	siphovirus Gp157 family protein	G8C7S9	Escherichia_phage	3.1e-08	27.5
WP_061943497.1\|103582_103930_-	hypothetical protein	NA	NA	NA	NA
WP_061943499.1\|103945_104170_-	hypothetical protein	A0A1S5SAD2	Streptococcus_phage	4.0e-16	54.1
WP_061943501.1\|104393_104579_-	hypothetical protein	NA	NA	NA	NA
WP_061946898.1\|104575_104887_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_061943504.1\|104886_105198_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_071884665.1\|105274_106027_-	hypothetical protein	C8CLG1	Xylella_phage	1.9e-38	40.3
WP_061943507.1\|106023_106242_-	hypothetical protein	NA	NA	NA	NA
WP_071530394.1\|106281_106509_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_037366602.1\|106622_106940_+	helix-turn-helix transcriptional regulator	A0A139ZPI6	Marinitoga_camini_virus	4.6e-10	47.9
WP_061943510.1\|106946_108026_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_061943513.1\|108222_110298_+	AAA family ATPase	NA	NA	NA	NA
WP_061943516.1\|110334_111009_+	Fic family protein	D7RWK9	Brochothrix_phage	4.9e-09	28.6
WP_071884732.1\|111054_111390_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_061943519.1\|111385_111580_-	hypothetical protein	NA	NA	NA	NA
WP_061943522.1\|111773_113045_+\|integrase	tyrosine-type recombinase/integrase	A0A2I7SCV1	Paenibacillus_phage	5.6e-38	28.8
WP_061943524.1\|113300_113792_-	hypothetical protein	NA	NA	NA	NA
WP_061943526.1\|114029_116477_-	DNA internalization-related competence protein ComEC/Rec2	Q332B9	Clostridium_botulinum_C_phage	2.3e-32	30.7
WP_061943528.1\|116473_117040_-	competence protein ComEA	NA	NA	NA	NA
WP_061943530.1\|117066_117861_-	adenosylmethionine decarboxylase	NA	NA	NA	NA
WP_061943532.1\|117890_119228_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	6.6e-90	42.2
WP_009442560.1\|119398_120796_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A2H5BJT2	Erwinia_phage	1.2e-36	27.1
WP_061943534.1\|120792_121332_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_009442562.1\|121328_122651_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
123167:123185	attR	NA	NA	NA	NA

DBSCAN-SWA_2

680564 : 688370

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061944564.1\|680564_681029_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	3.7e-40	57.5
WP_061944566.1\|681041_681659_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_061944568.1\|681676_682891_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.3e-105	50.0
WP_061944571.1\|683113_683749_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.4e-35	40.0
WP_061944574.1\|683758_684862_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	2.0e-39	34.7
WP_061944576.1\|685347_685734_-	dihydroxyacetone kinase	NA	NA	NA	NA
WP_061944579.1\|685735_686407_-	TerC family protein	W8EBD0	Pseudomonas_phage	3.6e-28	40.4
WP_061944581.1\|686417_688370_-	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	3.5e-108	36.7

DBSCAN-SWA_3

851007 : 884904

Clostridium_phage(30.77%)

protease,plate,terminase,tail,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157064399.1\|851007_851628_-\|protease	glycoprotease	NA	NA	NA	NA
WP_061944907.1\|851649_852201_-	N-acetylmuramoyl-L-alanine amidase	A0A142F1B8	Bacillus_phage	2.1e-13	33.1
WP_061946932.1\|852197_852701_-	endonuclease	NA	NA	NA	NA
WP_157064400.1\|852782_852947_-	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_061944910.1\|852949_853321_-	hypothetical protein	NA	NA	NA	NA
WP_083501146.1\|854742_855402_-	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_061944917.1\|855364_856462_-\|plate	baseplate J/gp47 family protein	H7BWD5	unidentified_phage	2.1e-81	43.5
WP_061944920.1\|856461_856899_-	DUF2634 domain-containing protein	X5JB38	Clostridium_phage	5.0e-23	45.2
WP_061944921.1\|856903_857311_-	DUF2577 domain-containing protein	S5MC71	Brevibacillus_phage	8.9e-06	29.1
WP_061946933.1\|857307_858264_-	hypothetical protein	H7BVH4	unidentified_phage	6.4e-79	48.4
WP_061944924.1\|858331_859039_-	hypothetical protein	X5J9Z8	Clostridium_phage	1.2e-26	34.9
WP_157064401.1\|859035_861108_-	tape measure protein	H7BVH2	unidentified_phage	3.8e-52	30.2
WP_061944931.1\|861181_861364_-	hypothetical protein	NA	NA	NA	NA
WP_061944941.1\|861366_862113_-	toxin Bro	A0A0A8WIE3	Clostridium_phage	5.6e-30	38.4
WP_071884678.1\|862542_863220_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_157064402.1\|863312_863843_-	hypothetical protein	NA	NA	NA	NA
WP_157064403.1\|864186_864336_-	hypothetical protein	NA	NA	NA	NA
WP_061944950.1\|864362_864794_-	hypothetical protein	NA	NA	NA	NA
WP_157064404.1\|864806_865289_-	hypothetical protein	A0A0A8WJ62	Clostridium_phage	1.5e-39	54.0
WP_061944953.1\|865307_866663_-\|tail	phage tail protein	X5JAJ1	Clostridium_phage	6.8e-119	48.1
WP_061944956.1\|866667_866868_-	hypothetical protein	NA	NA	NA	NA
WP_061944959.1\|866875_867298_-	hypothetical protein	A0A0A8WJT3	Clostridium_phage	6.4e-23	42.1
WP_061944962.1\|867287_867839_-	HK97 gp10 family phage protein	X2CXN4	Lactobacillus_phage	6.6e-12	46.6
WP_071884679.1\|867838_868207_-	hypothetical protein	NA	NA	NA	NA
WP_061944968.1\|868182_868545_-	hypothetical protein	NA	NA	NA	NA
WP_061944970.1\|868544_868727_-	hypothetical protein	NA	NA	NA	NA
WP_061944973.1\|868738_869659_-	hypothetical protein	A0A1S5SA65	Streptococcus_phage	5.6e-80	51.0
WP_061944976.1\|869677_870229_-	hypothetical protein	I1TLE1	Bacillus_phage	3.6e-10	33.3
WP_061944980.1\|870339_870690_-	hypothetical protein	A0A1P8BMG7	Lactococcus_phage	8.1e-16	41.4
WP_157064405.1\|870743_870899_-	hypothetical protein	NA	NA	NA	NA
WP_061944982.1\|871118_871313_-	hypothetical protein	NA	NA	NA	NA
WP_061944984.1\|871302_873129_-	hypothetical protein	X5JAI9	Clostridium_phage	6.3e-75	44.4
WP_157064406.1\|873169_874549_-\|portal	phage portal protein	S5MNW1	Brevibacillus_phage	4.4e-97	42.7
WP_061944986.1\|874561_875956_-\|terminase	phage terminase large subunit	A0A090EUA8	Clostridium_phage	2.4e-191	73.2
WP_061946936.1\|875948_876476_-\|terminase	terminase small subunit	U5PZD3	Bacillus_phage	5.7e-29	41.3
WP_061944988.1\|876801_877707_-	hypothetical protein	NA	NA	NA	NA
WP_061944991.1\|877709_878132_-	DUF4065 domain-containing protein	I6R0L8	Salmonella_phage	3.9e-12	30.9
WP_061944993.1\|878211_878703_-	hypothetical protein	NA	NA	NA	NA
WP_061944994.1\|878879_879371_-	class I SAM-dependent methyltransferase	A0A0E3Y6D6	Fusobacterium_phage	5.6e-55	61.3
WP_061944995.1\|879354_880341_-	DNA (cytosine-5-)-methyltransferase	A0A1P8DJM9	Virus_Rctr41k	1.2e-43	33.4
WP_061944998.1\|880340_880769_-	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	1.3e-18	48.0
WP_061946937.1\|880781_881063_-	hypothetical protein	NA	NA	NA	NA
WP_061946938.1\|881175_881775_-	ATP-binding protein IstB	A0A1B1P7U2	Bacillus_phage	3.2e-20	38.6
WP_061945001.1\|881920_882727_-	DnaD domain protein	NA	NA	NA	NA
WP_061945004.1\|882743_883049_-	hypothetical protein	NA	NA	NA	NA
WP_061945007.1\|883053_883713_-	hypothetical protein	A8ATM8	Listeria_phage	3.1e-16	32.2
WP_061945010.1\|883712_884249_-	hypothetical protein	NA	NA	NA	NA
WP_061945013.1\|884229_884904_-	AAA family ATPase	A0A2I7R7K9	Vibrio_phage	1.7e-25	34.3

DBSCAN-SWA_4

1231228 : 1288203

Faecalibacterium_phage(28.0%)

plate,transposase,tail,terminase,holin,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061945547.1\|1231228_1231789_+	hypothetical protein	A0A2K9V2V4	Faecalibacterium_phage	2.6e-24	34.1
WP_061945549.1\|1231808_1232606_+	ParA family protein	H7BUL8	unidentified_phage	7.0e-39	35.7
WP_061945551.1\|1232608_1233673_+	hypothetical protein	NA	NA	NA	NA
WP_061945553.1\|1233669_1234203_+	hypothetical protein	NA	NA	NA	NA
WP_061945555.1\|1234207_1234477_+	hypothetical protein	NA	NA	NA	NA
WP_061945557.1\|1234457_1235381_+	hypothetical protein	A0A0A7S0B8	Clostridium_phage	4.0e-86	52.5
WP_157064420.1\|1235368_1236103_+	hypothetical protein	A0A2K9V3X0	Faecalibacterium_phage	1.5e-27	42.8
WP_157064458.1\|1235841_1236807_+	hypothetical protein	A0A1P8DJM9	Virus_Rctr41k	2.5e-22	31.7
WP_061946955.1\|1236799_1238179_+	helicase	F4YCV3	Synechococcus_phage	1.1e-127	52.0
WP_061945563.1\|1238228_1239083_+	site-specific DNA-methyltransferase	A0A0F7L417	uncultured_marine_virus	2.4e-93	59.8
WP_061945565.1\|1239093_1239450_+	DUF4406 domain-containing protein	NA	NA	NA	NA
WP_157064421.1\|1239487_1239715_+	hypothetical protein	NA	NA	NA	NA
WP_157064422.1\|1239876_1240635_+	hypothetical protein	NA	NA	NA	NA
WP_061946956.1\|1240639_1241053_+	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_157064423.1\|1241101_1241302_+	hypothetical protein	NA	NA	NA	NA
WP_061945571.1\|1241460_1241979_+	hypothetical protein	NA	NA	NA	NA
WP_157064424.1\|1241950_1243768_+\|terminase	phage terminase large subunit family protein	A0A2K9V301	Faecalibacterium_phage	6.3e-128	41.1
WP_061945575.1\|1243836_1244040_+	hypothetical protein	NA	NA	NA	NA
WP_061945577.1\|1244036_1245557_+\|portal	phage portal protein	A0A2K9V303	Faecalibacterium_phage	2.0e-82	36.2
WP_061945579.1\|1245534_1246047_+	hypothetical protein	A0A2K9V308	Faecalibacterium_phage	6.5e-22	60.6
WP_061945581.1\|1246085_1247411_+	hypothetical protein	A0A2K9V304	Faecalibacterium_phage	2.6e-54	34.3
WP_061945583.1\|1247425_1247752_+	DUF2190 family protein	A0A2K9V343	Faecalibacterium_phage	1.4e-06	35.5
WP_061945585.1\|1247751_1248099_+	hypothetical protein	NA	NA	NA	NA
WP_061945586.1\|1248095_1248671_+	hypothetical protein	NA	NA	NA	NA
WP_061945588.1\|1248667_1249153_+	hypothetical protein	NA	NA	NA	NA
WP_039980878.1\|1249154_1249493_+	hypothetical protein	NA	NA	NA	NA
WP_061945590.1\|1249495_1250944_+\|tail	phage tail protein	A0A059WKP9	Vibrio_phage	3.6e-142	52.0
WP_061945592.1\|1250960_1251524_+\|tail	phage major tail tube protein	A0A067ZJA9	Vibrio_phage	1.2e-40	46.2
WP_061945594.1\|1251587_1251902_+	hypothetical protein	NA	NA	NA	NA
WP_061945596.1\|1252296_1255386_+\|tail	phage tail tape measure protein	D4HTW4	Vibrio_phage	3.9e-53	38.1
WP_009442506.1\|1255378_1255585_+\|tail	tail protein	NA	NA	NA	NA
WP_061945598.1\|1255588_1256602_+	hypothetical protein	A0A067ZG47	Vibrio_phage	1.4e-55	35.1
WP_061945601.1\|1256591_1256993_+\|plate	baseplate assembly protein	A0A067ZIM2	Vibrio_phage	7.6e-18	38.5
WP_071586069.1\|1257004_1257325_+	hypothetical protein	NA	NA	NA	NA
WP_061945603.1\|1257326_1257881_+\|tail	phage tail protein	NA	NA	NA	NA
WP_157064459.1\|1257892_1258198_+	hypothetical protein	A0A067ZJ13	Vibrio_phage	1.7e-14	43.2
WP_061945607.1\|1258184_1259303_+\|plate	baseplate J/gp47 family protein	A0A0C5AEG2	Bacteriophage	1.7e-86	46.5
WP_061945609.1\|1259295_1260036_+\|tail	phage tail protein I	A0A0C5AJ63	Bacteriophage	6.1e-29	40.5
WP_061945611.1\|1260048_1260837_+	hypothetical protein	A0A0C5AEQ0	Bacteriophage	1.6e-11	36.9
WP_061945613.1\|1260855_1261398_+	hypothetical protein	NA	NA	NA	NA
WP_061945615.1\|1261402_1261771_+	hypothetical protein	NA	NA	NA	NA
WP_157064400.1\|1261773_1261938_+	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_061945617.1\|1262002_1262293_+	hypothetical protein	NA	NA	NA	NA
WP_061945619.1\|1262304_1262808_+\|holin	phage holin family protein	Q0H258	Geobacillus_phage	2.4e-16	39.6
WP_061945621.1\|1262804_1263419_+	hypothetical protein	NA	NA	NA	NA
WP_071884697.1\|1263455_1264721_+	N-acetylmuramoyl-L-alanine amidase	A0A0A7RTQ5	Clostridium_phage	9.8e-19	35.2
WP_061945623.1\|1264717_1264921_+	hypothetical protein	NA	NA	NA	NA
WP_006690722.1\|1265955_1266231_+	hypothetical protein	NA	NA	NA	NA
WP_061945625.1\|1266311_1267673_+	beta-mannosidase	NA	NA	NA	NA
WP_061945627.1\|1267698_1268238_-	hypothetical protein	NA	NA	NA	NA
WP_061945630.1\|1268264_1268825_-	hypothetical protein	NA	NA	NA	NA
WP_061945632.1\|1268954_1269233_-	hypothetical protein	NA	NA	NA	NA
WP_061945634.1\|1269372_1270689_+	NCS2 family permease	NA	NA	NA	NA
WP_061945636.1\|1270698_1272432_+	adenine deaminase	NA	NA	NA	NA
WP_061945638.1\|1272649_1273240_+	hypothetical protein	NA	NA	NA	NA
WP_157064425.1\|1273933_1275058_+	hypothetical protein	NA	NA	NA	NA
WP_061945642.1\|1275054_1276707_+	hypothetical protein	NA	NA	NA	NA
WP_157064426.1\|1276886_1277027_+	hypothetical protein	NA	NA	NA	NA
WP_061946957.1\|1277988_1279137_+	NgoFVII family restriction endonuclease	NA	NA	NA	NA
WP_061945644.1\|1279148_1281008_+	restriction endonuclease	NA	NA	NA	NA
WP_061945646.1\|1281018_1281444_+	DNA mismatch endonuclease Vsr	E5E3X5	Burkholderia_phage	3.9e-28	45.9
WP_071884698.1\|1281499_1281892_+	hypothetical protein	NA	NA	NA	NA
WP_061945648.1\|1281963_1283010_-	DNA (cytosine-5-)-methyltransferase	M1PSQ0	Streptococcus_phage	4.3e-28	27.7
WP_071884699.1\|1282994_1283351_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_061945650.1\|1284537_1285719_-	MFS transporter	NA	NA	NA	NA
WP_061945652.1\|1286767_1287286_+	cysteine hydrolase	NA	NA	NA	NA
WP_061945654.1\|1287396_1288203_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA

DBSCAN-SWA_5

2108643 : 2114669

Synechococcus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061946676.1\|2108643_2109594_+	chemotaxis protein CheV	Q56AR1	Bacillus_thuringiensis_phage	2.2e-55	39.3
WP_009442369.1\|2109699_2110188_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	9.9e-20	38.8
WP_061946677.1\|2110227_2110941_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HI61	Synechococcus_phage	2.8e-47	43.7
WP_009442367.1\|2110946_2112398_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.0e-64	35.0
WP_061946999.1\|2112404_2113454_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.8e-66	42.3
WP_009442365.1\|2113446_2114079_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.2e-27	39.4
WP_061946678.1\|2114075_2114669_+	hypothetical protein	E3SNU8	Prochlorococcus_phage	4.9e-53	56.0

DBSCAN-SWA_6

2127208 : 2153836

Klosneuvirus(25.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050344111.1\|2127208_2127943_+\|tRNA	tRNA threonylcarbamoyladenosine dehydratase	NA	NA	NA	NA
WP_050344109.1\|2127939_2128920_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_061946687.1\|2128923_2129322_+	(deoxy)nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
WP_061946688.1\|2129678_2131184_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	1.5e-53	33.4
WP_006689518.1\|2131332_2131983_+	HAD family phosphatase	NA	NA	NA	NA
WP_009442334.1\|2132008_2132260_+	IreB family regulatory phosphoprotein	NA	NA	NA	NA
WP_061947001.1\|2132268_2132688_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_050344103.1\|2132751_2133057_+	DUF1292 domain-containing protein	NA	NA	NA	NA
WP_061946689.1\|2133153_2134257_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_061946690.1\|2134275_2135517_+	U32 family peptidase	Q6DW11	Phage_TP	1.4e-57	37.8
WP_009442329.1\|2135513_2135795_+	hypothetical protein	NA	NA	NA	NA
WP_061947003.1\|2135804_2136254_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_061946691.1\|2136243_2137320_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_009442326.1\|2137368_2137926_+	elongation factor P	NA	NA	NA	NA
WP_006689508.1\|2137952_2138360_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_009442325.1\|2138382_2138958_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_050344096.1\|2138970_2139213_+	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_009442323.1\|2139209_2139623_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_050344092.1\|2139694_2140903_+	exodeoxyribonuclease VII large subunit	A0A1V0SD82	Indivirus	4.2e-35	28.0
WP_006689503.1\|2140892_2141129_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_061946692.1\|2141130_2142006_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_061946693.1\|2142015_2142822_+	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_050344089.1\|2142837_2143692_+	NAD(+)/NADH kinase	NA	NA	NA	NA
WP_061946694.1\|2143703_2144156_+	arginine repressor	NA	NA	NA	NA
WP_061946695.1\|2144171_2145893_+	DNA repair protein RecN	NA	NA	NA	NA
WP_157064444.1\|2145892_2146408_+	DUF4367 domain-containing protein	NA	NA	NA	NA
WP_061946696.1\|2146541_2147372_+	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_083501183.1\|2147368_2148484_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_083501184.1\|2148688_2149312_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_061946698.1\|2149439_2150405_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_061946699.1\|2150457_2151111_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_061946700.1\|2151163_2151793_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_061946701.1\|2151845_2152475_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_061946702.1\|2152798_2153836_-\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	7.4e-57	36.8

DBSCAN-SWA_7

2360797 : 2431539

unidentified_phage(23.08%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061947031.1\|2360797_2361295_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_061946843.1\|2361403_2363056_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_009442176.1\|2363229_2363766_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_061946844.1\|2363820_2365446_+	GDSL family lipase	NA	NA	NA	NA
WP_061946845.1\|2365492_2366524_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_061946846.1\|2366590_2367742_-	SpoIID/LytB domain-containing protein	Q2XU88	Pseudomonas_phage	4.3e-29	33.6
WP_061946847.1\|2367757_2368360_-	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_009442182.1\|2368361_2369399_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	2.9e-08	30.5
WP_061946848.1\|2369420_2370020_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_061946849.1\|2370092_2370587_-	crossover junction endodeoxyribonuclease RuvC	NA	NA	NA	NA
WP_061946850.1\|2370653_2371382_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_061946851.1\|2371414_2372617_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	1.4e-59	33.4
WP_061946852.1\|2372635_2374723_-	penicillin-binding protein 1A	NA	NA	NA	NA
WP_061946853.1\|2375024_2377382_-	endonuclease MutS2	NA	NA	NA	NA
WP_061946854.1\|2377440_2379921_-	peptidase U32	Q6DW11	Phage_TP	2.0e-31	29.6
WP_061946855.1\|2379953_2380547_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	8.1e-16	34.5
WP_009442191.1\|2380533_2381262_-	hypothetical protein	NA	NA	NA	NA
WP_009442192.1\|2381270_2381900_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_009442193.1\|2381909_2382461_-	NUDIX hydrolase	NA	NA	NA	NA
WP_071884731.1\|2382498_2383461_-	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
WP_061946857.1\|2383460_2387021_-	chromosome segregation protein SMC	NA	NA	NA	NA
WP_061946858.1\|2387165_2388164_+	class II fructose-1,6-bisphosphate aldolase	NA	NA	NA	NA
WP_061945451.1\|2388290_2388764_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	1.4e-15	37.5
WP_061946859.1\|2388974_2389688_-	HAD family hydrolase	NA	NA	NA	NA
WP_061946860.1\|2389822_2390764_-	transketolase family protein	NA	NA	NA	NA
WP_061946861.1\|2390766_2391618_-	transketolase	A0A2K9L6P9	Tupanvirus	2.3e-27	33.2
WP_061946862.1\|2391821_2392859_+\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	1.7e-56	37.1
WP_061946863.1\|2393045_2394734_-	ribonuclease J	NA	NA	NA	NA
WP_061946864.1\|2395047_2396475_-	argininosuccinate lyase	NA	NA	NA	NA
WP_061946865.1\|2397699_2398635_-	ornithine carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	5.0e-20	31.7
WP_061946866.1\|2398696_2399902_-	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_061946867.1\|2399911_2400796_-	acetylglutamate kinase	NA	NA	NA	NA
WP_061946868.1\|2400806_2402018_-	bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ	NA	NA	NA	NA
WP_061946869.1\|2402039_2403074_-	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
WP_061946870.1\|2403361_2404312_-	homoserine kinase	NA	NA	NA	NA
WP_061946871.1\|2404308_2405610_-	homoserine dehydrogenase	NA	NA	NA	NA
WP_061946872.1\|2405701_2406283_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_061946873.1\|2406279_2407605_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_061946874.1\|2407631_2409023_-	DUF512 domain-containing protein	NA	NA	NA	NA
WP_061946875.1\|2409052_2410762_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_061946876.1\|2410758_2411838_-	flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA	NA	NA	NA
WP_061946877.1\|2411846_2412887_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_061946878.1\|2412907_2413729_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_009442216.1\|2413744_2414539_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	1.2e-17	37.3
WP_009442217.1\|2414621_2414855_-	hypothetical protein	NA	NA	NA	NA
WP_009442218.1\|2414854_2415412_-	ribosome recycling factor	NA	NA	NA	NA
WP_039980801.1\|2415408_2416134_-	UMP kinase	NA	NA	NA	NA
WP_061946879.1\|2416253_2417120_-	elongation factor Ts	NA	NA	NA	NA
WP_009442221.1\|2417192_2417897_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_039980803.1\|2418109_2418676_-	cell division protein SepF	NA	NA	NA	NA
WP_061946880.1\|2418909_2419947_+\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	1.1e-57	37.4
WP_061946881.1\|2420013_2421831_-	translational GTPase TypA	NA	NA	NA	NA
WP_009442225.1\|2422005_2422563_-	hypothetical protein	NA	NA	NA	NA
WP_061946882.1\|2428420_2429158_+	thiamine diphosphokinase	NA	NA	NA	NA
WP_061946883.1\|2429175_2429955_+\|tRNA	tRNA 2-thiocytidine biosynthesis protein TtcA	A0A0U2S5Z2	Escherichia_phage	2.4e-23	30.0
WP_061947033.1\|2429958_2430309_-	hypothetical protein	NA	NA	NA	NA
WP_061946884.1\|2430468_2431539_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	3.3e-68	41.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP014239

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection