CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012199	Sphingopyxis granuli strain TFA chromosome, complete genome	2 crisprs	DEDDh,cas3,csa3,RT,WYL,DinG,cas1	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012199_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012199_1

1982489-1982753

Orphan

Consensus_repeat	Method
CCATCGTGCAATGCCCCATCGCCGC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP012199_1

>merge|NZ_CP012199|1|1982489-1982753|CRISPRCasFinder
CTGGCCGGCAATGGCCCATCGCGGCGTGCTCGGGCGGGCAGGGGACGGCGGGCTTCGCCGGTACCGGCGGCGGCGCTTCCAGTGTGCAGTGCCCCATGGCAGCATGCTCCGCCGTGCAGCCGGGTGCGTTCGGTTCGTGGCGCGGAGGCGCCGGGTCCATCGTGCAATGCCCCATCGCCGCATGCTCGGCGGAGCATGCGGTCGTAGGCTCTTCCGGCGCCGGCTTTTCGGGCGGTGGCGCCATCGTGCAATGCCCCATCGCCGC

>NZ_CP012199|1|1|1982489-1982753|CRISPRCasFinder
CTGGCCGGCAATGGCCCATCGCGGC	GTGCTCGGGCGGGCAGGGGACGGCGGGCTTCGCCGGTACCGGCGGCGGCGCTT
CCAGTGTGCAGTGCCCCATGGCAGC	ATGCTCCGCCGTGCAGCCGGGTGCGTTCGGTTCGTGGCGCGGAGGCGCCGGGT
CCATCGTGCAATGCCCCATCGCCGC	ATGCTCGGCGGAGCATGCGGTCGTAGGCTCTTCCGGCGCCGGCTTTTCGGGCGGTGGCG
CCATCGTGCAATGCCCCATCGCCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012199.1\|WP_067182843.1\|1988915_1989485_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP012199.1\|WP_067111865.1\|1969779_1970886_-\|rod-shape-determining-protein-RodA	unknown	unknown	gnl\|CDD\|274033
NZ_CP012199.1\|WP_148650843.1\|1989700_1990330_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_CP012199.1\|WP_067182829.1\|1985348_1985762_+\|MerR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|133410
NZ_CP012199.1\|WP_067182821.1\|1977562_1978027_-\|MaoC-family-dehydratase	unknown	unknown	gnl\|CDD\|239538
NZ_CP012199.1\|WP_067182815.1\|1974241_1975288_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237562
NZ_CP012199.1\|WP_082737176.1\|1982824_1984678_-\|copper-resistance-system-multicopper-oxidase	unknown	unknown	gnl\|CDD\|273649
NZ_CP012199.1\|WP_067182811.1\|1970882_1972802_-\|penicillin-binding-protein-2	unknown	unknown	gnl\|CDD\|274573
NZ_CP012199.1\|WP_067182837.1\|1987433_1988429_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187632
NZ_CP012199.1\|WP_067182835.1\|1986176_1987274_-\|redox-regulated-ATPase-YchF	unknown	unknown	gnl\|CDD\|236583
NZ_CP012199.1\|WP_067182840.1\|1988508_1988919_-\|GNAT-family-acetyltransferase	unknown	unknown	gnl\|CDD\|235142
NZ_CP012199.1\|WP_067182826.1\|1984569_1985307_-\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|223767
NZ_CP012199.1\|WP_067182824.1\|1980038_1981610_-\|alkaline-phosphatase-D-family-protein	unknown	unknown	gnl\|CDD\|226070
NZ_CP012199.1\|WP_067182818.1\|1975483_1977319_+\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|234630
NZ_CP012199.1\|WP_067182832.1\|1985813_1986113_-\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NZ_CP012199.1\|WP_067182846.1\|1990639_1991536_-\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|350614
NZ_CP012199.1\|WP_067182813.1\|1973326_1974220_-\|rod-shape-determining-protein-MreC	unknown	unknown	gnl\|CDD\|237560
NZ_CP012199.1\|WP_067111828.1\|1972808_1973330_-\|rod-shape-determining-protein-MreD	unknown	unknown	unknown
NZ_CP012199.1\|WP_067186996.1\|1978163_1979777_+\|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl\|CDD\|349937
NZ_CP012199.1\|WP_067182808.1\|1968366_1969530_+\|cystathionine-gamma-synthase	unknown	unknown	gnl\|CDD\|131135

Protein	Function_ID	Function_description	E-value
NZ_CP012199.1\|WP_067182843.1\|1988915_1989485_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	3.63502e-89
NZ_CP012199.1\|WP_067182824.1\|1980038_1981610_-\|alkaline-phosphatase-D-family-protein	gnl\|CDD\|226070	COG3540, PhoD, Phosphodiesterase/alkaline phosphatase D [Inorganic ion transport and metabolism].	5.84607e-154
NZ_CP012199.1\|WP_148650843.1\|1989700_1990330_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	1.20306e-83
NZ_CP012199.1\|WP_067182829.1\|1985348_1985762_+\|MerR-family-DNA-binding-protein	gnl\|CDD\|133410	cd04783, HTH_MerR1, Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator. Helix-turn-helix (HTH) transcription regulator MerR1. MerR1 transcription regulators, such as Tn21 MerR and Tn501 MerR, mediate response to mercury exposure in eubacteria. These proteins are comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain winged HTH motifs that mediate DNA binding, while the C-terminal domains have three conserved cysteines that define a mercury binding site. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	9.37134e-55
NZ_CP012199.1\|WP_067182832.1\|1985813_1986113_-\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	7.2913e-50
NZ_CP012199.1\|WP_067182815.1\|1974241_1975288_-\|rod-shape-determining-protein	gnl\|CDD\|237562	PRK13927, PRK13927, rod shape-determining protein MreB; Provisional.	0
NZ_CP012199.1\|WP_082737176.1\|1982824_1984678_-\|copper-resistance-system-multicopper-oxidase	gnl\|CDD\|273649	TIGR01480, unnamed_protein_product, copper-resistance protein, CopA family. This model represents the CopA copper resistance protein family. CopA is related to laccase (benzenediol:oxygen oxidoreductase) and L-ascorbate oxidase, both copper-containing enzymes. Most members have a typical TAT (twin-arginine translocation) signal sequence with an Arg-Arg pair. Twin-arginine translocation is observed for a large number of periplasmic proteins that cross the inner membrane with metal-containing cofactors already bound. The combination of copper-binding sites and TAT translocation motif suggests a mechansism of resistance by packaging and export. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0
NZ_CP012199.1\|WP_067182811.1\|1970882_1972802_-\|penicillin-binding-protein-2	gnl\|CDD\|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP012199.1\|WP_067182837.1\|1987433_1988429_-\|SDR-family-oxidoreductase	gnl\|CDD\|187632	cd05374, 17beta-HSD-like_SDR_c, 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. 17beta-hydroxysteroid dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.21593e-71
NZ_CP012199.1\|WP_067182835.1\|1986176_1987274_-\|redox-regulated-ATPase-YchF	gnl\|CDD\|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NZ_CP012199.1\|WP_067182840.1\|1988508_1988919_-\|GNAT-family-acetyltransferase	gnl\|CDD\|235142	PRK03624, PRK03624, putative acetyltransferase; Provisional.	2.37413e-60
NZ_CP012199.1\|WP_067182826.1\|1984569_1985307_-\|glutaredoxin-family-protein	gnl\|CDD\|223767	COG0695, GrxC, Glutaredoxin and related proteins [Posttranslational modification, protein turnover, chaperones].	9.07908e-11
NZ_CP012199.1\|WP_067111865.1\|1969779_1970886_-\|rod-shape-determining-protein-RodA	gnl\|CDD\|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	1.75089e-155
NZ_CP012199.1\|WP_067182818.1\|1975483_1977319_+\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0
NZ_CP012199.1\|WP_067182846.1\|1990639_1991536_-\|TraB/GumN-family-protein	gnl\|CDD\|350614	cd14789, Tiki, Tiki homology domain antagonizes Wnt function via cleavage of amino-terminal residues. Tiki is a membrane-associated metalloprotease that inhibits Wnt via the cleavage of its amino terminus, diminishing Wnt's binding to receptors. Wnt is essential in animal development and homeostasis. In xenopus, tiki is critical in head development. In human cells, TIKI inhibits Wnt-signaling, which is important in embryogenesis, homeostasis, and regeneration. Deregulation of WNT contributes to birth defects, cancer and various diseases. TIKI homology domains are part of the TraB family and are related to the Erythromycin esterase, GumN plant pathogens, RtxA toxins, and Campylobacter Jejuni heme-binding, Chan-like proteins. TraB/PrgY are identified in gut bacterium Enterococcus faecalis, but its function has not been well characterized. Plasmid-borne, TraB has been implicated in the regulation of pheromone sensitivity and specificity. Based on homology to TIKI activity, it has been proposed that TraB acts as a metalloprotease in the inactivation of mating pheromone. The TIKI/TraB family has 2 conserved GxxH motifs and conserved glutamate and arginine residues that may be catalytic.	2.89228e-63
NZ_CP012199.1\|WP_067182813.1\|1973326_1974220_-\|rod-shape-determining-protein-MreC	gnl\|CDD\|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	2.11112e-54
NZ_CP012199.1\|WP_067182821.1\|1977562_1978027_-\|MaoC-family-dehydratase	gnl\|CDD\|239538	cd03454, YdeM, YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	2.38054e-70
NZ_CP012199.1\|WP_067186996.1\|1978163_1979777_+\|M20/M25/M40-family-metallo-hydrolase	gnl\|CDD\|349937	cd08015, M28_like, M28 Zn-peptidase-like; uncharacterized subfamily. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions.	3.46518e-86
NZ_CP012199.1\|WP_067182808.1\|1968366_1969530_+\|cystathionine-gamma-synthase	gnl\|CDD\|131135	TIGR02080, Cystathionine_gamma-synthase, O-succinylhomoserine (thiol)-lyase. This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family].	0

>NZ_CP012199.1|WP_067182824.1|1980038_1981610_-|alkaline-phosphatase-D-family-protein
MLNRRHFLATATLAGLSAPAILRAEAGFFRDFPFSLGVAAGDPASDGFVIWTRLAPEPMAPHGGMPLVPVPVEWEVASDGGFRDVVAKGTELARPELGHSVHVEVAGLQPDRPYYYRFVAGGERSLRGRARTLPAPGARADALKFGVCGCQHYESGFYGAYRHLAREDLAFVYHYGDFIYEYQQDYLYDSGLPIRPVRRYALRGLQDLGDFRTAYTQTLLDIDMQAARSAHGFISSFDDHEIRNDWVSTFDDWKLGLDGNDPDAPPPEVFMLRKQAAMQAWYEHMPVRRALLPRGGMVAAHRELRYGDLMAMQVLDTRQYRGNQPCGDGFKPACPDVYAKDAQVLGKAQEEWLARNLAKGGATWNTIAQQVTMMSLDRRRRPDEPEKIINIDSWAGYEAPRERILSRFAGLKNCVVLTGDEHQNFCGDLVLKDKVVAAEFVGTSISSGGDGSDKRAGTDEWLARNPELKFANDQRGYLVCEVGREAWQTHFMVVDKVTTPVNTLSKRATGVVENGRPGITMSA
>NZ_CP012199.1|WP_067186996.1|1978163_1979777_+|M20/M25/M40-family-metallo-hydrolase
MRRTWIAMAMAGAAFVAVPAAGQKADDADTNAIIDQGFNHSQVMRIAQEMTDGLGPRLTNSPAMRRAEQWAIDRFAGWGLANVRREGFEFGRGWEILSVDVRMTAPRPLALTAIPIAWTPSTGGAITAPIVVAPMSKEEHFAEWKGKLAGKIVLVTLPGTGDEPEKAPFRRLGGEDFEKLDAYRQPKYDPDAINKRLERVSFAEKLDAFLKAEGAVAWVRQSYRDGKLVHGEGYNYRVGHTLSLPGVELAAEDYRRLARLAKSGPAPQLSIDSNVRFDDSDTKAYNIIADIPGSDPKAGYVMAGAHFDSWVAGDGATDNAAGSAVVMEAARILKTLGVRPKRTIRFVLWTGEEQGLLGSLAYVDKHLATRPGPTEGEDGNALYYGWPNRYPVTPRPGYGDLKAYFNMDNGSGKLRGVYAEGNVAAVPLLQAWLAPFASMGAGKVVAAPTGGTDHVYMQSVGVPGFQFIQDPLDYGSRTHHSSADTFDHLKADDLRQASVVMAGMLLASANSDKTLPRFPVPSQPAPYDPFQYKDPDQ
>NZ_CP012199.1|WP_067182821.1|1977562_1978027_-|MaoC-family-dehydratase
MLYYEDIAVGKIQRFGSKLVTREEVVDFASRYDPQPFHLDDEAAAQTYFGRLSASGWHTGAMAMRMMVDHMKAHEQAGLGSPGIDELRWLKPVYPGDTLRCEMEVVEKRRSAKRPDMGILSSKLTVLNQHDEPVMTMRSAGLIRVRDAAGNGQA
>NZ_CP012199.1|WP_067182818.1|1975483_1977319_+|DNA-mismatch-repair-endonuclease-MutL
MSIRRLPEKLVNRIAAGEVVERPAAALKELVENAIDSGATRISVRIAEGGIARLEVEDDGCGMTPAEMALALERHATSKLPGDAIEDVTTLGFRGEALPSIASVARMTLESRVAGGDGWRRVVDNGALAGEGPAALAKGTRVVVEDLFARVPARRKFLRSARSEYASCLDGVKRLAMARPDIGFTVEHDGRRVLDVQGGQDRLARVAALTSRELADNSIGVDLDRGEVHLGGVISLPTYNRGIADHQYLFVNGRPVKDRLLVGALRGAYADLLARDRHPVVALFLDLPTGEVDVNVHPAKTEVRFRDPQLVRGMIVGGLRRALDEHGFRSVQRPAEAALAAWRQEPVASMPHPAMEQPMTGFLFGHRTEPAVHLFGADAPPPAEDVARVYDRLTPFSGAAAPIAGRAEVAEAPPPAAGAHPLGIARGQIAKTYIVAEAEDGLVIVDQHAAHERLVLETLRRGMAGQGVASQGLLLPEVVELDEPACDRLEAASPQLAALGVELERFGPTAVMVRATPAMLGTIDCRKLVTDIADDLAGYDAALGLSEKLELVAATMACHGSVRAGRTLAVAEMNALLRQMEVTPHSGQCNHGRPTWVKLAMDDVEKLFGRK
>NZ_CP012199.1|WP_067182815.1|1974241_1975288_-|rod-shape-determining-protein
MSFFSRFLKFNSQDMAIDLGTANTVVYVRGKGIVLNEPSVVAVETLNGIKRVKAVGDDAKLMMGKTPDTIEAIRPLRDGVIADIDVAEQMIKHFITKVHGGKPNAFRSPEIVICVPSGSTSVERRAIRDAASNAGASQVWLIEEPMAAAIGADMPVTEPIGSMVVDIGGGTTEVAVLSLRGLAYTTSVRAGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDFGIARIPSDGVGLTIHIKGRDLVNGVPKEISINQAQIAEALSEPIGTIVEGVRIALENTAPELAADIVDQGIVLTGGGALIAELDELLRDATGLPVTVAEDPLTCVAIGTGRAMEDPAFRGVLQQA
>NZ_CP012199.1|WP_067182813.1|1973326_1974220_-|rod-shape-determining-protein-MreC
MVRPAHRRPGQSRKAQYGLFAAYVIAVTGAVAGLLLAILSVVDPVGFTTLRVASHEVAAPIARVTRSVTGSISGIDDAVSAYVGAGSQNRRLRKELAETRRKLVATSSLEEENRQLKALLQLQQTDKAALAHGYLLTSTSTSSRRLALLSIGRNVGVAAGQPVRGADGLIGRVLTAGPSVSQVLLLTDVDNVVPVRRARDGLPALANGRGNGDLDIRTLNIANNPFKPGDILVTSGTGGLYPPNIPVAIVVRRQDDGALARPLADPAKVDAVAVLRPYTPDNLEARAAPAAPPAGTP
>NZ_CP012199.1|WP_067111828.1|1972808_1973330_-|rod-shape-determining-protein-MreD
MNRAGPRLGEPASLWRMRIVPIASVMLASALPLMLPLVASSPVLPPMGLLFFLCWQLLRTEMWPVWIGLPLGLWDDLFSGAPIGTAIGLWTLASIAIHYFSQRIYWRGFFHDWGIAALLAAAVQAAAALIAHPHAPAGHLLGLVVPQIIVSALLVPLFLRLTGAFDNFRLKRR
>NZ_CP012199.1|WP_067182811.1|1970882_1972802_-|penicillin-binding-protein-2
MRRKNPRQTMPITEAWRGMTFTRRTLLVGGGQMAVGAALATRMAYISVVDNDRYVLESESNRVNLTLVPPRRGWIVDRHGKALANNRVSLRIDIIPDRLHNKDLVLGQLRTLLRLDGDAMDRIERDLKAASGFQPVAVAEDVTEQDYSAVLVRLPDLSGIAPARGFARNYPTGAAVGHLIGYVGAPNAEEYEKAKNPLYITPGFKIGKDGLEKYFEDVLKGKPGARRVEVTARGKVVRDLSTQPDVQGKTVHLTIDADLQEYVARRMGRESGAAIVIDCLNGDILSFVSMPSFDPNSFSDGISNSEYAWLRADDHQPLINKATRGLYPPGSTLKPMAAIAAMEHGVDPGEKHTCIGGYRLGSRFFRCLGRHGTIDMPTAIEKSCNSYFYWLGHRLGYDAIAPTARLLGLGEEYQLAGSAQRYGTIPDSEWKMRKYHREWSASDSLNAVIGQGYVLANPLQLAVMAARIASGRALYPRLINRQFENKPLPFAEEHLAVAREGMNRVVNGPGTAVRSRLPLDGIAMAGKTGTAQVRGLASGGNGKGGTWKYRDHGLFVCFAPVDNPRYAASVVIEHGMGGSRAAAPVAKDIFTFLYDREKAMAALEGFEAGWGGTITERMNRDYAAWKAGASSDPEPGAPR
>NZ_CP012199.1|WP_067111865.1|1969779_1970886_-|rod-shape-determining-protein-RodA
MIPVPPAIQRIPWKLIALLSAITGFGLLVLYSAAGGNASPWALQQGTRFAIFLTMALAIGRIPLRFFEDFSYLGYLGVAVLLVAVELLGFVGGGSQRWLNLGFMNLQPSELMKVAIVLALARFYTQLPPGETRSWTALWPALVMIGIPAALVMLQPDLGTALAICASGAIVMFVAGLPLWWFGSAVIAGAAALPILFSMLHDYQQKRVLIFLDPESDPLGAGYHISQSKIAIGSGGISGKGFLNGSQSHLDYLPEGHTDFIFATMAEEWGLIGGLALMFGFFLLLRWSTRVAMNARTRFGQLVATGLTMTIFFYIAINLMMVMGLAPVVGIPLPLFSYGGSSMLTIMTCVGIVLAIENDSRTGVRRFH
>NZ_CP012199.1|WP_067182808.1|1968366_1969530_+|cystathionine-gamma-synthase
MTERAEGLRPETIAAAHGVASDVAFGAIAPPLYLSSTYEFAGFEQPRAYDYGRAANPTRDLLATALAKLEGGAGAILTASGMAALDLIVSRLPAGAVVIAPHDCYGGTMRLLKAREQLGQVSLRLVDQRDGDAVAAVLSGAPALMLIETPSNPLLRVVDIAALAARAKAAGAAVAVDNTFLSPALQRPLALGADYVIHSTTKYLNGHSDVIGGAVVAADAEQAASLSQWANIVGCGGSPFDAWLTLRGLRTLFPRMRQQQANAMAIARMLSDHPAVSAVHYPGLETHPDHALAARQQQGFGAMLSFDLAGGAAAAKRLVAALRVFTFAESLGGVESLIVHPATMTHADMGDDARRVAGIGEGLLRVSVGIEAEHDLIEDMKAGLAAC
>NZ_CP012199.1|WP_082737176.1|1982824_1984678_-|copper-resistance-system-multicopper-oxidase
MRLRRRRQQGAAGLRLADRESGHDRNGAVDDRNAAVIDAIGRRALIAGGAAAALTPWLPLWAKPVSAGLPTVSGPDVRLTIAHQTLAIDGRDHHAIGINGTIPGPLIRLTEGTQARLHVTNRLDEDSSIHWHGLILPFHMDGVPGISFPGIAPGATFTYEFPVRQAGTYWYHSHSGLQEQMGHYGPIVIDPAGADPVAHDREHVILLSDFSPLHPHAIFRKLKQMGGYFNHRKQTLSGLLAGRDQPLKDRIAWGAMRMDPTDISDVTAAAYRYLVNGHGPADNWTGLFRAGERVRLRIINASAMTTFNIRIPGLPMTVVQADGCNVRPVTVDEFQIGVAETYDVIVTPEDRAYTLVGETSDRSGMARATLAPRAGMAAPVPALRPRPVLTMKDMGMGGMNHGGNHGGGPACAPEHAAMGHCTPDAAGGHGGGMDHGMRDMTLAPTVRDTPAVQSISPMPADRTGEPGIGLEGVERALTYRDLIALDRNPDTRAPTRQMQIHLTGNMERYMWAFDGVKMNEVKAPIPFTQGERVRVTLVNDTMMTHPIHLHGHFFELVTGKGDHAPRKHTVNVQPGGKLSFDLTADAYGDWAFHCHLLYHMHAGMMQVVTVRPAGDAA
>NZ_CP012199.1|WP_067182826.1|1984569_1985307_-|glutaredoxin-family-protein
MTKQAILYRMVMPDHICPYGLKAKHLLKSRGFAVDDRWLTTRAETDAFKTEHGVKTTPQTFIDGVRIGGHDDLRRHFGLKVADPDATSYTPVIALFAMTALMALATSFAAYGDAFTLRAAEWFVSFSMIVLALLKLQDVDKFATMFLNYDLLARRWVPYASIYPFAEGLAGVLMTAHALPWLSIPVALFIGGIGAVSVFKAVYIDRRSIKCACVGGGSKVPLGFVSLTENLGMIAMALWMIGTLP
>NZ_CP012199.1|WP_067182829.1|1985348_1985762_+|MerR-family-DNA-binding-protein
MQLTIGKLASAGGVGVETVRYYQRRGLMATPVRSGGERWGGGIRRYGADDLRRLRFIRSAQAAGFTLDEISELLALEESNDRARVRLLARQRIDALDRKIAQMTETRAALARLADQCAASDAGDGRGPCPILAAFEP
>NZ_CP012199.1|WP_067182832.1|1985813_1986113_-|GIY-YIG-nuclease-family-protein
MHPDAQPAVYIMANRKDGVLYTGVTSDLIGRTWQHRQKASGFSARYRCDKLVWFEIYDDMLSAIAREKQIKAGSRARKIALIEAKNPGWRDLFPELAGG
>NZ_CP012199.1|WP_067182835.1|1986176_1987274_-|redox-regulated-ATPase-YchF
MGFKCGIVGLPNVGKSTLFNALTETQAAQAANYPFCTIEPNIGNVAVPDDRLDKLAAIAGSQKIIPTQLAFVDIAGLVRGASKGEGLGNQFLGNIREVDAIVHVLRCFEDDDIQHVENKVDPVADAETVETELLLSDLESLEKRVPAFQKKATGGDKEAKAAASVLGQALDLLRAGKPARLTEPKDPEEERILRQAQLLTTKPVLYVCNVEEANAATGNAHSDAVFARAKAEGAQAVLVSAAIESELVGMEAEERMLFLEEMGLHETGLARVIRAGYELLHLLTFFTVGPKEARAWTVHAGATAPEAAGEIHSDFQKGFIRAETIAFADYVALGGEAKAREAGKLRAEGKGYVVQDGDVMHFLHS
>NZ_CP012199.1|WP_067182837.1|1987433_1988429_-|SDR-family-oxidoreductase
MPDRNRPARRDLIAGAAALAATAPTLLHAAAPTALPSLTGRTVLITGTSSGFGRIGALHYARLGAKVIATMRNLPRPEADTLAAEAAKEKLDLHIVEIDVTSDDSVAAGTASALEAAGGRIDTLINNAGVGISGPIEVQDMEATHLAFNTNVIGMQRMIRALLPQMRAARAGQIVNISSQLGRVIVPGGGHYSATKFAVEALSEQLAYELVPHGIEVTIIQPGGYPTRVWQNRNVYTGALKERSDPERLAAYEPFTRGMGTEDGSGRSADPADVPRAIAEIMAMPAGTRPLRRAVHPGPKPQEAINRVAAEVQVAWLGGSPLGPLIRAVHD
>NZ_CP012199.1|WP_067182840.1|1988508_1988919_-|GNAT-family-acetyltransferase
MTITRAATAADRDAVIAIWEICALTRPWNDPAADFQRALDHDASTIFVAERSAEIIGTAMTGFDGHRGWIYYLGVAPNRQGQGIARRLLDAACEWLRLRGCPKVELMLRDGNPASGLYEHLGWEPQDVRVFARWLT
>NZ_CP012199.1|WP_067182843.1|1988915_1989485_-|aminoacyl-tRNA-hydrolase
MQLWVGLGNPGPQYAMHRHNVGFMAVDVIADAHGFAAPAKKFQGWVQDGRIGRHRILLLKPSTFMNESGRSVRAALDFYKLTPQDVTVFYDELDLAPMKVKVKRGGGAAGHNGIRSLIQHIGDDFRRVRIGIGHPGHKDRVTGYVLGPYHKSEIEPLTDLLGAIAAEAGGLADGDDARFLNDLALRLQA
>NZ_CP012199.1|WP_148650843.1|1989700_1990330_-|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MSDQLTLTAETRERAGKGASRELRRNGRVPAVVYGGNEDPLMIHVEEKLLMKQLMTGVFLNSVVMIEVGGKTIRTLPKDVAFHPVKDRPIHADFLRVSKDTKVQVGVPVLFVNEEKSPGLKRGGVLNVVRHELELICEADKIPDDITIDVTGFDVGESIHISHVTLPQGVESAITDRDFTIATIVAPSALKSSDGDTTKDEGEAAEGEA
>NZ_CP012199.1|WP_067182846.1|1990639_1991536_-|TraB/GumN-family-protein
MTRRRWHRRRGGRAAAALAFLLFVGCGSAEPPREARPAMWLVADPDTRIYLLGTMHALPRGTDWDGGKVAEAMRAADALVMELSPDELAAAGAVFGQLAPRSAPLAIDRRLSGEALGGYRRLEAKGGDFGGDRLDDWAVMVLMGQRTAALAKLSPDAGVEAGLTAAFRDADKPIGGLETAKAQLLLFETLPPEAQRTLLERAASRADSAPREVGALADAWSRGDVAALEAVINADVEAVPAARKAILTDRNRRWSAWVKRRMDRPGTLLVAVGAGHLIGPEGVPALLEADGLTVTRVQ

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Crispr_ID: NZ_CP012199_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012199_2

4127701-4127789

Orphan

Consensus_repeat	Method
CCCCTCCCGCAAGCGGGAGGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012199_2

>merge|NZ_CP012199|2|4127701-4127789|CRISPRCasFinder
CCCCTCCCGCAAGCGGGAGGGGGTAGGGGCGGGCCAGCGGCCTGCCCGGAACGAGCCCACCCCCGACCCCTCCCGCAAGCGGGAGGGGG

>NZ_CP012199|2|2|4127701-4127789|CRISPRCasFinder
CCCCTCCCGCAAGCGGGAGGGGG	TAGGGGCGGGCCAGCGGCCTGCCCGGAACGAGCCCACCCCCGA
CCCCTCCCGCAAGCGGGAGGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012199.1\|WP_067186173.1\|4134536_4136297_+\|fatty-acyl-AMP-ligase	unknown	unknown	gnl\|CDD\|236403
NZ_CP012199.1\|WP_067186152.1\|4117923_4118694_-\|isocitrate-lyase/phosphoenolpyruvate-mutase-family-protein	unknown	unknown	gnl\|CDD\|379346
NZ_CP012199.1\|WP_067112971.1\|4121573_4121822_+\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NZ_CP012199.1\|WP_067186174.1\|4136402_4138757_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NZ_CP012199.1\|WP_067186164.1\|4123654_4125184_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|236448
NZ_CP012199.1\|WP_067186171.1\|4133782_4134355_-\|RecX-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|234646
NZ_CP012199.1\|WP_067186162.1\|4123049_4123616_+\|F0F1-ATP-synthase-subunit-delta	unknown	unknown	gnl\|CDD\|235593
NZ_CP012199.1\|WP_067186158.1\|4121808_4122096_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|224937
NZ_CP012199.1\|WP_082737480.1\|4131583_4132369_+\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NZ_CP012199.1\|WP_067112951.1\|4127800_4128058_+\|ATP-synthase-F1-subunit-epsilon	unknown	unknown	gnl\|CDD\|184058
NZ_CP012199.1\|WP_067112953.1\|4125260_4126136_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|235535
NZ_CP012199.1\|WP_067112978.1\|4118690_4119725_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	unknown	unknown	gnl\|CDD\|185333
NZ_CP012199.1\|WP_148650926.1\|4130488_4130674_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012199.1\|WP_067113816.1\|4128737_4130231_+\|CpaF-family-protein	unknown	unknown	gnl\|CDD\|227297
NZ_CP012199.1\|WP_067111910.1\|4132814_4133201_-\|NADH:ubiquinone-oxidoreductase-subunit-NDUFA12	unknown	unknown	gnl\|CDD\|236176
NZ_CP012199.1\|WP_082737358.1\|4126150_4127692_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|236447
NZ_CP012199.1\|WP_067186156.1\|4120006_4121542_+\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379142
NZ_CP012199.1\|WP_082737481.1\|4133291_4133738_-\|DUF192-domain-containing-protein	unknown	unknown	gnl\|CDD\|376876
NZ_CP012199.1\|WP_067186160.1\|4122092_4122782_-\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223489
NZ_CP012199.1\|WP_067186168.1\|4130753_4131587_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|227135

Protein	Function_ID	Function_description	E-value
NZ_CP012199.1\|WP_067186173.1\|4134536_4136297_+\|fatty-acyl-AMP-ligase	gnl\|CDD\|236403	PRK09192, PRK09192, fatty acyl-AMP ligase.	0
NZ_CP012199.1\|WP_067186152.1\|4117923_4118694_-\|isocitrate-lyase/phosphoenolpyruvate-mutase-family-protein	gnl\|CDD\|379346	pfam13714, PEP_mutase, Phosphoenolpyruvate phosphomutase. This domain includes the enzyme Phosphoenolpyruvate phosphomutase (EC:5.4.2.9). This protein has been characterized as catalyzing the formation of a carbon-phosphorus bond by converting phosphoenolpyruvate (PEP) to phosphonopyruvate (P-Pyr). This enzyme has a TIM barrel fold.	1.02741e-76
NZ_CP012199.1\|WP_067112971.1\|4121573_4121822_+\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	6.15075e-09
NZ_CP012199.1\|WP_067186174.1\|4136402_4138757_+\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.09768e-109
NZ_CP012199.1\|WP_067186164.1\|4123654_4125184_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0
NZ_CP012199.1\|WP_067186171.1\|4133782_4134355_-\|RecX-family-transcriptional-regulator	gnl\|CDD\|234646	PRK00117, recX, recombination regulator RecX; Reviewed.	5.51378e-09
NZ_CP012199.1\|WP_067186162.1\|4123049_4123616_+\|F0F1-ATP-synthase-subunit-delta	gnl\|CDD\|235593	PRK05758, PRK05758, F0F1 ATP synthase subunit delta; Validated.	5.77115e-57
NZ_CP012199.1\|WP_067186158.1\|4121808_4122096_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	3.96893e-20
NZ_CP012199.1\|WP_082737480.1\|4131583_4132369_+\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	3.13396e-107
NZ_CP012199.1\|WP_067112951.1\|4127800_4128058_+\|ATP-synthase-F1-subunit-epsilon	gnl\|CDD\|184058	PRK13449, atpC, ATP synthase F1 subunit epsilon.	1.02126e-42
NZ_CP012199.1\|WP_067112953.1\|4125260_4126136_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|235535	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated.	5.4045e-138
NZ_CP012199.1\|WP_067112978.1\|4118690_4119725_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	gnl\|CDD\|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	1.72996e-107
NZ_CP012199.1\|WP_067113816.1\|4128737_4130231_+\|CpaF-family-protein	gnl\|CDD\|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	3.56988e-156
NZ_CP012199.1\|WP_067111910.1\|4132814_4133201_-\|NADH:ubiquinone-oxidoreductase-subunit-NDUFA12	gnl\|CDD\|236176	PRK08183, PRK08183, NADH:ubiquinone oxidoreductase subunit NDUFA12.	5.82254e-68
NZ_CP012199.1\|WP_082737358.1\|4126150_4127692_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NZ_CP012199.1\|WP_067186156.1\|4120006_4121542_+\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.50325e-19
NZ_CP012199.1\|WP_082737481.1\|4133291_4133738_-\|DUF192-domain-containing-protein	gnl\|CDD\|376876	pfam02643, DUF192, Uncharacterized ACR, COG1430. Two structures have been solved for members of this large (>500 members) family of bacterial proteins present mostly in environmental bacteria and metagenomes (distant homologs are also present in several Plasmodium species). TOPSAN analysis for Structure 3pjy shows that there is much similarity with the other solved structure, Structure 3m7a, solved for UniProt:Q2GA55 (Saro_0823), a homolog of Thermotoga maritima TM1668, UniProt:Q9X1Z6., The homolog in Caulobacter crescentus (CC1388), UniProt:Q9A8G6, is associated with CspD, a cold shock protein (CC1387), UniProt:Q9A8G7. However, the genomic context of UniProt:Q2GA55 is most conserved with a putative xylose isomerase, suggesting a possible role in extracellular sugar processing. Saro_0821, UniProt:Q2GA57, is annotated as an AMP-dependent synthetase and ligase. Structure 3m7a structure corresponds to the C-terminal (27-165) fragment of the YP_496102 (Saro_0823) protein and it is structurally unique, as the best hits from Dali have a Z-score of 3.8 (1nt0, 2j1t, 3kq4) and it is thus a likely candidate for a new fold. Interestingly, many of the top Dali hits are involved in sugar metabolism. There are no obvious active site-like cavities on the protein surface of 3m7a (http://www.topsan.org/Proteins/JCSG/).	1.98927e-49
NZ_CP012199.1\|WP_067186160.1\|4122092_4122782_-\|dienelactone-hydrolase-family-protein	gnl\|CDD\|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	5.23305e-43
NZ_CP012199.1\|WP_067186168.1\|4130753_4131587_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|227135	COG4798, COG4798, Predicted methyltransferase [General function prediction only].	3.4567e-52

>NZ_CP012199.1|WP_082737358.1|4126150_4127692_+|F0F1-ATP-synthase-subunit-beta
MATAPAPEKKAPAKKAAAPKKPAASKAAAPKKAAAGAATGRVAQVIGAVVDVQFDGALPAILNALETDNGGNRLVLEVAQHLGENTVRTIAMDATDGLTRGQPVTDTGAQISVPVGPQTLGRILNVIGDPIDERGPINSDMTAPIHAKAPEFVDQSTEAAILVTGIKVIDLLAPYARGGKIGLFGGAGVGKTVLIQELINNIAKGHGGVSVFAGVGERTREGNDLYHEFLDAGVIAKDADGNPTPEGSKVALVFGQMNEPPGARARVALSGLTMAEYFRDQEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGALQERITSTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRAISELGIYPAVDPLDSTSRVLEPRVVGQEHYETARRVQETLQKYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFHVAEVFTNIPGKFVQIEDTIKSFKAVVDGEYDHLPEAAFYMVGGIEEAVAKAAKLAAEAA
>NZ_CP012199.1|WP_067112953.1|4125260_4126136_+|F0F1-ATP-synthase-subunit-gamma
MASLKELKGRINSVKSTQKITKAKKMVAAAKLRKAQAAAEAARPYAERLEGVVASLASKVGAADGAPKLLSGTGKSDTHLLLVLNSDRGLAGAFNSNIVKAARDKAHELQAAGKTVRFFLVGRKGRPVINRLFPGQIIENYETTGIREIGFEQAREVAEKISELFEAGAFDVAHLFYSKFRSALVQEATGQQLIPVPAPDEAPASSGAAVEYEPDEEAILADLLPRNVTIQIFKGLLENAASEQGASMTAMDNATRNAGDLINKLTIQYNRSRQAAITTELVEIISGAEAL
>NZ_CP012199.1|WP_067186164.1|4123654_4125184_+|F0F1-ATP-synthase-subunit-alpha
MEIRAAEISKVIKDQIANFGTDATVSEIGQVLSVGDGIARVHGLDNVQAGEMVEFANGVKGMALNLEADNVGIVIFGSDAEIKEGDTVKRTGTIVDVPVGKGLLGRVVDGLGNPIDGKGPIKADKRMRVEVKAPGIIPRQSVHEPVQTGLKALDALVPVGRGQRELIIGDRQTGKTAVAIDTFINQREVNKGDDESKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPAPLQYLAPYTGVTMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNADNGSGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETNLFYQGIRPAINVGLSVSRVGSAAQTKAMKKVSGSIKLELAQYREMEAFAQFGSDLDAATQKLLNRGARLTQLLKQPQFHPMPFEEQTASIFAGTNGYLDTVAVNDVTRYEAAMLAYLRSDHADVLKMIRDTKDLGDDAKKGLVAALDAFAKIFA
>NZ_CP012199.1|WP_067186162.1|4123049_4123616_+|F0F1-ATP-synthase-subunit-delta
MENSGGIQGNITAGLAGRYASALFDLARESDAIDSVRQSLATLKAGLAESADLAALTQSPVVGRADAAKAVAAVAKSLGLDSLTTKFLGVLAENRRLADLGGMIDAFDAIVSAHRGEVTAKVTSAHPLSAEQLKALAANLKTRVGRDVQIATTVDPAILGGLVVQLGSQLIDGSIRTRLNSFAQAMKG
>NZ_CP012199.1|WP_067186160.1|4122092_4122782_-|dienelactone-hydrolase-family-protein
MGEMIRMTMDDGAEIAVYHAQPEGERRGGLVLIQEIFGVTDHIRELCDEYAADGYEVLAPALFDREHPGFESDYSGPQFERAVELARQLHPFEQSLKDAQTCIDALKGANGSGGPVFITGYCYGGSVAWRMAQTSPDLAAASCYYGSLVPTQFADQAPQCAAIAHFGRFDAGIPMEGVEALITREHPTAQIFVYEAGHGFNSDRRKDYHEPSAELARERTLMLFRACGG
>NZ_CP012199.1|WP_067186158.1|4121808_4122096_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MTTYNLDFFKDAKKEWDRLDKSVRAQFRKKLTQRLANPHIPSARLSGMANCYKIKLRSAGYRLIYQVEDETITVVVVAIGKRERNEAYEEAKRRL
>NZ_CP012199.1|WP_067112971.1|4121573_4121822_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MGKPLLADFGISISELKKNPSAAIRAADGAPVAILNRNTPEAYLVPADAWEAILDALDDIELARIVRERQGQERIRVSIDDL
>NZ_CP012199.1|WP_067186156.1|4120006_4121542_+|trypsin-like-peptidase-domain-containing-protein
MTRLLPLLLAFFAIVLPARAADDISAASRSVVRVVTVAMMEGEVVGFGHGSGIAITPTRILTNAHVVESAVRYPNNVALGVVPSEGQKSYPARLIAIDTARDLALIEMGEGRLPAAAIYTRPLESGTDVVALGYPGNVDLATARSAADYITPRTPVRSEGNMSNVQAVDGIATLVHTAKISRGNSGGPLVDACGRVVGINTFITRADDGDSPFAFAISVREIARFLADAGQQYTSVGTACLSMAEATARDRAALDAETRAAAEAEAAKTAAARLDRELKQARAEEAALASRENRIALAGVLFVIGALAAGAGLLFYSQKAMRNAKIAGGAGAVLMIGAAILFVTRPDAHAEIAGETEQAPAPDVAPKLAQGNFLCTIQPDRSRITVSSTIDVPVEIGGDGCINRRTQYAQGTDGRWQRILVPNEEATVTIASIDDGAHEYRVERYLLDAETMAKARALRAAAEIKGCAADPQALAAFATQQDAIKGALPPTPNERLVYRCQKVAGSAAATP
>NZ_CP012199.1|WP_067112978.1|4118690_4119725_-|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada
MSAGTMTDDECWAAVQRRDRALDGRFVTGVLTTGIYCRPSCAARHPARANVRFFADGAAARAAGLRPCKRCLPDDVARDEGAVIAAIAAIKGSEEPLALADLAARTGYSPTHFQRVFTRHTGLSPAAYARALREERARTALSEGARVTDAIYDAGFSGPSRFYDNMEGRMGMTASAWVNGGKGVTIHWAVVPTSLGDMLVAATGKGVCRLSFAEGREALEERFPAATLVEGDAAFAALLTQVIEAVETPAAGFDHIPIDVKGTAFQEAVWRELRKIPAGETRSYADIAAAVGKPKAVRAAGSANGANNVAVLIPCHRVVRSDGSLGGYAYGLPIKRELLKREIP
>NZ_CP012199.1|WP_067186152.1|4117923_4118694_-|isocitrate-lyase/phosphoenolpyruvate-mutase-family-protein
MTPTSSSAIAAFRALHVPGDPLILVNIWDAGSAKAVAAAGARAIATGSYGVAGAQGRADGEDFPLDDALENLRRILDVTDLPVTIDMESGYGADPAAVGASISRAREAGAAGVNIEDRLPGASELLPIAAAQARYRAAADTGLFVNARCDVFRGWDAGKDGAALVAATLERARAYSDAGAGSLFVPFLADAGCIGAICEASPLPVNILRSSVGPTHAELAALGVARISHGHQPWAAAMAWLTAQAETVLGGGEPAY
>NZ_CP012199.1|WP_067112951.1|4127800_4128058_+|ATP-synthase-F1-subunit-epsilon
MALKFELVTPARLERSSDVHMVTVPGSEGDFSVLEGHAPFMTTLRNGPLTIYASAGAAPETIEVEGGFAEVNEAGLTVLAERIAG
>NZ_CP012199.1|WP_067113816.1|4128737_4130231_+|CpaF-family-protein
MSAFGRRPGTAGRPAFGVAKPMQTGPGVPGGSQFPPIEPAPAAHDPAPSPLSPELEAMERLNQRSSAENMEPERAQGFEASVHKIKEQVLPRLLERVDPEAAATLSKDELTEEFRPIILEVLAELRITLNRREQFALEKVLVDELLGFGPLEELLADPDISDIMVNGPYQTYVERKGQLVIAPIQFRDEQHLFQIAQRICNQVGRRVDQTTPLADARLKDGSRVNVIVPPLSLRGTAISIRKFSAKPITLDMLCQWGAMSQKMCTALKIAGASRFNIVISGGTGSGKTTMLNALSKMIDPGERVLTIEDAAELRLQQPHWLPLETRPANLEGNGAIHMGDLVKNALRMRPDRIIMGEVRGAECFDLLAAMNTGHDGSMCTLHSNSPRECLGRMENMVLMGDIKIPKEAISKQIADSVDLIVQIKRLRDGSRRVTNVTEVIGMEGDVIVTQELFKFEYLDEDKDGKIVGEYRSMGLRPYTLEKARQFGFDQPYLEACL
>NZ_CP012199.1|WP_148650926.1|4130488_4130674_-|hypothetical-protein
MQVSMLSVSIGAVVLFGIAEIAEWRRKHRHDVDRVGFMPWRGIALASIAVALFAAAFALKG
>NZ_CP012199.1|WP_067186168.1|4130753_4131587_+|class-I-SAM-dependent-methyltransferase
MRHFRPVAIAALLAASAACSAPSSNAAAGEAAAQPSDAIAAAVAAPTRTAANLPRDAYRHPAETLAFFGVTGRDTVVELWPGGGWYTEILAPLARAGGGTLYAAAPWERGLNKIKEWQGAHPDVYGAVRLAEFPATGAGPKVPDGSADVVLTFRNVHNWRFGGADKTADAFKQIYAMLKPGGVLGVVEHRLPEEMDSAREEKSGYMKRSSIVAFAEAAGFRLAGESDINANPKDTHDYEKGVWTLPPTLTEGEKDKDKYLAIGESDRMTLKFVKPAS
>NZ_CP012199.1|WP_082737480.1|4131583_4132369_+|leucyl/phenylalanyl-tRNA--protein-transferase
MTKPLETIDPALLLSAYAQGLFPMADGADDPSVHWVEPRLRAILPLDGFHLSHSLRKVIVADRFRVTTDTAFPAMMALCAEPAPDRPTTWINPIIKASYERLFRLGHAHSVECWLGDALVGGLYGVSLGRAFFGESMVSRVRDASKVALAHLVARLKAGGWQLLDCQFITPHLASLGAIEIPQAAYLARLYSVLSGVEGGAAGGVAGAGGGDGGAGAAVVPSPPFVAGDWGALDALGAASDLGAARATGSPPGYVIAQLLT
>NZ_CP012199.1|WP_067111910.1|4132814_4133201_-|NADH:ubiquinone-oxidoreductase-subunit-NDUFA12
MSILGKIFTWWDGATVGTLLNSWKNGEKVGEDSLGNRYYRARKGNRRWVIYNGSNDASRVPPEWHGWLHGTLDELPSEALPAPRPWQAEPTPNLTGSLGAYRPAGALERGGRRAAATGDYEAWRPGAE
>NZ_CP012199.1|WP_082737481.1|4133291_4133738_-|DUF192-domain-containing-protein
MMTAFALVLALPVTACAKDSDAQSQSATVPLTVAMMGVQHKFQVEVARTAEEQARGLMFRTSLPADGGMIFPFTPPRPASFWMKNTLIPLDMIFIRADGSIDRIAENTIPESLEPVVSGGDVAAVLELAGGTAARLGIDETATVTWKN
>NZ_CP012199.1|WP_067186171.1|4133782_4134355_-|RecX-family-transcriptional-regulator
MSHSRVPSDRRKKPLDAARLDELALAYVARFATSRAKLTRYLARKVRESEWQGDADAMAACDAVADRMERLRFLDDRQYAAMRAGAMTRRGLGVRRVKAQLFVDGIADEDSGEAIAEAEERAMAAAVGFARRRRFGPFATRAADDPAQRERQVAAFVRAGHAPALARRILAIAPGDDAALAALDGEAALD
>NZ_CP012199.1|WP_067186173.1|4134536_4136297_+|fatty-acyl-AMP-ligase
MTQKNNVAPNDTVAPTPTPTECAQPRRFSDFATVGEALAYAAAGTRGLNFHDPRGRLVRAYSYRELRDDAIATAYRLIAAGVQPGDRIALIAETGAEFAALFFGTIHAGAWPVPLPLPTSFGGRDSYVGQLVVQLESCDPALLFFPPDIAAMAIEAAKAKGVTPVDWDEFAARPAPVAPLPEQKSDETCYLQYSSGSTRFPHGVAVTHAALLNNLAAHAHGMKLQDSDRCVSWLPWYHDMGLVGCFLSPVANQVSVDYLKTEDFARRPLAWLDLISRNEGTTLSYSPTFGYDICARRISSQTNVADRFDLSRWRVAGNGADMIRPDVMQAFVDAFAEAGFQAGAFLPSYGLAEATLAVSIMPPGEGIVVELVEETELSGAAGNGDRPTRYRAIVNCGRAVRDMTIEVRDEEGHVLPDQTVGKVWCTGPSLMTGYYRDPDATAACMQDGWLDTGDMGYLSDGYIYIVGRAKDMIIINGKNHWPQDIEWAVEQLPGFKSGDIAAFAITAPGGEETPAVLVQCRTSDEAERVALREAIRDRVRAITGMNCLVELIPPRTLPRTSSGKLSRSKARAQYLAGEIQPFAIAA
>NZ_CP012199.1|WP_067186174.1|4136402_4138757_+|EAL-domain-containing-protein
MKSLLTDQNPADDVSVRTLLGLGASHRDIAHLRQLQLAPLRGRGSLRLWMGVAMALIAAFTMVPHVRSVIVAGWLTCALSFSLWSYRSFATRPLGEARIAGPAEFALCNRHAFYSALLWTVPFWLQGLSPGTDHALAMWATTLLMMLTLAMIAHSLPTVCILYIAPVSLSAAVALVRAGAPQLAVVAVAAGLLLSFFCIRFAQNHIRFRRAEEVLHEKSETVSLLLREFEETSADWLWQTDSNRRLVHVSPRLAYALGAAADALEGQPLVQALSGDAWETGNFPRSLHDMAERMKRRESFSNLIVPVTIGGKPRWWELSASPRLDEAGKFLGFRGVGSDVTEQRVSAEQIAKMARFDNLTGLPNRLSLNEALARALDQAQSARSRCALLMIDLDRFKAVNDTLGHPIGDKLLAQVAARLKGMMDRSMTCGRLGGDEFAVVLHQAPSADEAEEMARRIIATLSRPYVVDNHQLFVGASVGYAIGPQDGATVETLTRNADLALYKSKDKGGNVVAAYVASLHAQAEERRVMEQELRGALDRGEFELYYQPVVTAEDGTLNGFEALIRWTNQKLGSVPPGRFIPLAEDSRLIAPIGEWVLRTACHEAMRWPANLKVAINVSAEQLTDPNFASVVVSALAQSGLPPHRLEIEVTESVFLRDGGGAAQLLDQLIGLGIRLSLDDFGTGYSSLGYLRKTQFSTIKVDRSFVVGAAKGSIESIAIIRAVVALADSLGMSTTAEGAETEIEVDTLRALGCSNIQGYYYGRPMPAADVLTLFRPPENLATAAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

920672 : 934168

Caulobacter_phage(14.29%)

portal,head,transposase,protease,tail,capsid

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_067180923.1\|920672_921635_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_148650792.1\|921773_922610_+	hypothetical protein	NA	NA	NA	NA
WP_172709609.1\|922876_923020_+	hypothetical protein	NA	NA	NA	NA
WP_148650793.1\|923016_923226_+	hypothetical protein	NA	NA	NA	NA
WP_067180931.1\|923426_924044_+	hypothetical protein	NA	NA	NA	NA
WP_067180934.1\|924315_925650_+	DNA-packaging protein	A0A0K1LMR9	Caulobacter_phage	3.9e-66	38.0
WP_067180935.1\|925817_926924_+\|portal	phage portal protein	A0A0K1LLE7	Bacillus_phage	1.7e-43	33.7
WP_067180938.1\|926937_927246_+	hypothetical protein	K4I011	Acidithiobacillus_phage	2.6e-10	50.0
WP_082737413.1\|927290_927695_+\|head,protease	HK97 family phage prohead protease	A0A2H4JAI0	uncultured_Caudovirales_phage	2.7e-10	35.8
WP_082737065.1\|927700_928840_+\|capsid	phage major capsid protein	Q8W627	Enterobacteria_phage	3.8e-86	49.3
WP_067180940.1\|929001_930747_+\|tail	tail fiber domain-containing protein	A0A218KRF6	Acinetobacter_phage	8.8e-10	26.8
WP_172709610.1\|930743_930902_+	hypothetical protein	NA	NA	NA	NA
WP_067180943.1\|930918_931200_+	hypothetical protein	NA	NA	NA	NA
WP_067180946.1\|931196_931742_+	hypothetical protein	NA	NA	NA	NA
WP_172709611.1\|931741_932152_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_067112904.1\|932238_932577_-	hypothetical protein	NA	NA	NA	NA
WP_067112902.1\|932623_933031_+\|tail	phage tail protein	NA	NA	NA	NA
WP_067180952.1\|933027_933342_+	gene transfer agent family protein	NA	NA	NA	NA
WP_082737415.1\|933426_933600_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_067180958.1\|933592_934168_+\|tail	tail tape measure protein	A0A1B1P750	Rhodovulum_phage	5.7e-06	31.2

DBSCAN-SWA_2

1836732 : 1918591

Stx2-converting_phage(21.05%)

integrase,transposase,tRNA

attL 1884650:1884709|attR 1888288:1888373

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_067182539.1\|1836732_1838013_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.5e-88	45.1
WP_148650965.1\|1838491_1839298_+	hypothetical protein	NA	NA	NA	NA
WP_067106274.1\|1839979_1840441_+	RNA polymerase-binding protein DksA	NA	NA	NA	NA
WP_067106277.1\|1840534_1840927_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_076074740.1\|1840977_1841136_-	YdcH family protein	NA	NA	NA	NA
WP_067106279.1\|1841262_1841460_+	DUF465 domain-containing protein	NA	NA	NA	NA
WP_067106309.1\|1841554_1841995_+	DUF1465 family protein	NA	NA	NA	NA
WP_067182542.1\|1842079_1842541_+	hypothetical protein	NA	NA	NA	NA
WP_067182545.1\|1842562_1843642_-	DUF2332 domain-containing protein	NA	NA	NA	NA
WP_067186983.1\|1843680_1844355_+	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_067182546.1\|1844355_1845660_+	histidinol dehydrogenase	NA	NA	NA	NA
WP_067106287.1\|1845656_1846109_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_067182548.1\|1846220_1847153_+	thiamine-phosphate kinase	NA	NA	NA	NA
WP_067182549.1\|1847332_1849435_+	sodium-translocating pyrophosphatase	NA	NA	NA	NA
WP_067182551.1\|1849596_1850409_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_067106297.1\|1850725_1851256_+	CarD family transcriptional regulator	NA	NA	NA	NA
WP_067182552.1\|1851340_1852081_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_067108408.1\|1852337_1853258_-\|tRNA	methionyl-tRNA formyltransferase	NA	NA	NA	NA
WP_067108324.1\|1853456_1854053_+	recombination protein RecR	NA	NA	NA	NA
WP_067182555.1\|1854084_1854618_+	peptide deformylase	E3SLL2	Synechococcus_phage	6.8e-22	43.2
WP_067108330.1\|1854782_1855334_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_067108332.1\|1855338_1856382_-	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_067108335.1\|1856489_1857206_+	ribonuclease PH	NA	NA	NA	NA
WP_067182558.1\|1857207_1857849_+	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	E9KZD2	Cassava_brown_streak_virus	7.4e-07	40.3
WP_067182561.1\|1857907_1858423_+	DUF2239 family protein	NA	NA	NA	NA
WP_067182565.1\|1858454_1859600_+	coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_067182567.1\|1859645_1860536_+	tyrosine recombinase XerC	A0A1I9SC88	Mycobacterium_phage	3.8e-09	33.2
WP_067182568.1\|1860543_1861152_-	DedA family protein	NA	NA	NA	NA
WP_067182570.1\|1861206_1862157_-	glutathione synthase	NA	NA	NA	NA
WP_067182572.1\|1862200_1862551_-	YraN family protein	NA	NA	NA	NA
WP_067182573.1\|1862547_1863408_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_067108411.1\|1863418_1864606_+	penicillin-binding protein activator	NA	NA	NA	NA
WP_067182575.1\|1864786_1865323_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	9.9e-13	38.2
WP_067186984.1\|1865338_1866040_-	NRDE family protein	NA	NA	NA	NA
WP_067182576.1\|1866125_1866563_+	hypothetical protein	NA	NA	NA	NA
WP_067182577.1\|1866602_1868108_-	peptidase S10	NA	NA	NA	NA
WP_082737441.1\|1868200_1868422_-	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_067182578.1\|1868421_1868676_-	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_067182581.1\|1868802_1870989_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_172709637.1\|1871093_1871615_+	DUF3617 domain-containing protein	NA	NA	NA	NA
WP_067182585.1\|1872200_1873958_+	hypothetical protein	NA	NA	NA	NA
WP_003039428.1\|1874230_1874467_+	acyl carrier protein	NA	NA	NA	NA
WP_067182587.1\|1874636_1875899_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_067182590.1\|1876064_1877003_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_067182596.1\|1877101_1877854_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_067182600.1\|1878009_1878573_+	2'-5' RNA ligase family protein	NA	NA	NA	NA
WP_067182615.1\|1878881_1880135_+\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	3.6e-74	39.8
WP_067182617.1\|1880360_1881020_-	transglycosylase SLT domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	6.9e-24	48.5
WP_067182619.1\|1881147_1882056_+	toprim domain-containing protein	A0A2I6UG20	Salinibacter_virus	2.8e-07	39.5
WP_067182621.1\|1882159_1884628_+	strawberry notch family protein	NA	NA	NA	NA
1884650:1884709	attL	NA	NA	NA	NA
WP_067182623.1\|1884766_1885771_-\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	1.0e-10	33.9
WP_067182626.1\|1885767_1886682_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_067182629.1\|1886675_1888223_-\|integrase	tyrosine-type recombinase/integrase	A0A0K2CP59	Brevibacillus_phage	1.9e-11	30.6
WP_067182632.1\|1888279_1890124_+	strawberry notch C-terminal domain-containing protein	A0A076FMQ0	Aureococcus_anophage	6.2e-14	30.7
1888288:1888373	attR	NA	NA	NA	NA
WP_067182635.1\|1890179_1890593_+	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_082737163.1\|1890589_1891309_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_067182641.1\|1891475_1892993_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.3e-98	39.2
WP_067182644.1\|1893024_1893381_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_067186985.1\|1893377_1893815_-\|transposase	transposase	NA	NA	NA	NA
WP_067182647.1\|1894273_1894843_-	plasmid pRiA4b ORF-3 family protein	NA	NA	NA	NA
WP_067182650.1\|1894948_1895785_-	ATP-binding protein	NA	NA	NA	NA
WP_079639878.1\|1895781_1897296_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_067182653.1\|1897524_1899066_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	5.4e-120	45.8
WP_006963110.1\|1899119_1899467_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	1.9e-33	59.8
WP_052182212.1\|1899463_1899820_-\|transposase	transposase	NA	NA	NA	NA
WP_067182655.1\|1900116_1900563_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_067182658.1\|1900559_1900916_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_067182660.1\|1900947_1902465_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.4e-99	39.6
WP_067182668.1\|1903359_1904877_-	acyl--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.5e-29	30.2
WP_172709638.1\|1905148_1905904_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_067182671.1\|1906073_1908338_+	TonB-dependent receptor	NA	NA	NA	NA
WP_067182673.1\|1908383_1909676_+	MFS transporter	NA	NA	NA	NA
WP_067182676.1\|1909700_1910828_+	alcohol dehydrogenase catalytic domain-containing protein	NA	NA	NA	NA
WP_067182679.1\|1910837_1911302_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_067182681.1\|1911298_1912186_-	alpha/beta hydrolase	A0A249XTE1	Mycobacterium_phage	1.2e-07	37.6
WP_067182684.1\|1912185_1914357_-	TonB-dependent receptor	NA	NA	NA	NA
WP_082737167.1\|1914508_1916053_-	carboxylesterase family protein	S4VZJ7	Pandoravirus	1.8e-38	35.6
WP_148650832.1\|1916248_1916404_+\|transposase	transposase	NA	NA	NA	NA
WP_148650833.1\|1917441_1918591_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.8e-51	44.5

DBSCAN-SWA_3

2085239 : 2091645

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_067183027.1\|2085239_2086247_+	beta-N-acetylhexosaminidase	A0A1B1IVS3	uncultured_Mediterranean_phage	8.1e-16	37.2
WP_067106537.1\|2086254_2087028_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	5.1e-34	34.2
WP_067183031.1\|2087024_2087618_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.3e-34	41.0
WP_067106498.1\|2087643_2087871_+	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	1.2e-07	61.4
WP_067183033.1\|2087909_2088350_+	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_067183036.1\|2088346_2089156_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	8.7e-37	37.7
WP_067106494.1\|2089175_2089307_-	entericidin A/B family lipoprotein	NA	NA	NA	NA
WP_067183039.1\|2089551_2091015_-	magnesium transporter	NA	NA	NA	NA
WP_067183041.1\|2091195_2091645_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	2.2e-34	52.2

DBSCAN-SWA_4

3102634 : 3162313

uncultured_Mediterranean_phage(16.67%)

integrase,transposase

attL 3140946:3140963|attR 3168863:3168880

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052182212.1\|3102634_3102991_+\|transposase	transposase	NA	NA	NA	NA
WP_006963110.1\|3102987_3103335_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	1.9e-33	59.8
WP_067182653.1\|3103388_3104930_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	5.4e-120	45.8
WP_079639878.1\|3105158_3106673_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_067182650.1\|3106669_3107506_+	ATP-binding protein	NA	NA	NA	NA
WP_067182647.1\|3107611_3108181_+	plasmid pRiA4b ORF-3 family protein	NA	NA	NA	NA
WP_148650883.1\|3111066_3112294_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.9e-104	68.4
WP_067187100.1\|3113277_3117003_-	ATPase	NA	NA	NA	NA
WP_148650884.1\|3117030_3117489_-	BREX-3 system P-loop-containing protein BrxF	NA	NA	NA	NA
WP_067184740.1\|3117481_3118378_-	WYL domain-containing protein	NA	NA	NA	NA
WP_067184745.1\|3118787_3119432_+	helix-turn-helix transcriptional regulator	A5X9F5	Aeromonas_virus	1.9e-18	38.2
WP_082737276.1\|3119443_3119869_+	hypothetical protein	NA	NA	NA	NA
WP_082737459.1\|3119976_3120168_+	hypothetical protein	NA	NA	NA	NA
WP_067184748.1\|3120167_3120365_+	hypothetical protein	NA	NA	NA	NA
WP_067187101.1\|3120398_3120638_-	hypothetical protein	NA	NA	NA	NA
WP_067184751.1\|3120710_3123647_-	conjugative relaxase	NA	NA	NA	NA
WP_067184754.1\|3123684_3126069_-	type IV secretion system DNA-binding domain-containing protein	NA	NA	NA	NA
WP_082737277.1\|3126058_3126391_-	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_148650885.1\|3126543_3126774_-	hypothetical protein	NA	NA	NA	NA
WP_020820072.1\|3126830_3127025_+	hypothetical protein	NA	NA	NA	NA
WP_067184757.1\|3127127_3127364_-	hypothetical protein	NA	NA	NA	NA
WP_067184760.1\|3127549_3127918_+	hypothetical protein	NA	NA	NA	NA
WP_007688363.1\|3128032_3128422_-	single-stranded DNA-binding protein	A0A1P8L6D9	Staphylococcus_phage	8.5e-14	35.5
WP_067184763.1\|3128725_3129154_-	hypothetical protein	A0A1B1IUL8	uncultured_Mediterranean_phage	2.1e-34	63.1
WP_067184766.1\|3129164_3129626_-	hypothetical protein	NA	NA	NA	NA
WP_067184769.1\|3129747_3130701_-	DUF2493 domain-containing protein	NA	NA	NA	NA
WP_067184772.1\|3131006_3131429_-	hypothetical protein	NA	NA	NA	NA
WP_082737278.1\|3131440_3131737_-	antirestriction protein ArdC	A0A1B1IWW8	uncultured_Mediterranean_phage	6.5e-06	42.2
WP_037485796.1\|3131733_3132636_-	DUF1738 domain-containing protein	A0A1B1IWW8	uncultured_Mediterranean_phage	1.1e-32	35.0
WP_037485793.1\|3132693_3134901_-	hypothetical protein	NA	NA	NA	NA
WP_067179944.1\|3134897_3136685_-	hypothetical protein	NA	NA	NA	NA
WP_081796380.1\|3136681_3138073_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_067184778.1\|3138226_3138976_-	DUF1738 domain-containing protein	A0A1V0EBY3	Caulobacter_phage	7.1e-41	44.5
WP_067184781.1\|3139143_3141132_-	ParB/RepB/Spo0J family partition protein	NA	NA	NA	NA
3140946:3140963	attL	NA	NA	NA	NA
WP_067184784.1\|3141480_3141777_-	DCL family protein	NA	NA	NA	NA
WP_067184787.1\|3141790_3144400_-	DEAD/DEAH box helicase	M1HAU1	Paramecium_bursaria_Chlorella_virus	1.4e-11	22.9
WP_067184790.1\|3144396_3145359_-	DUF1837 domain-containing protein	NA	NA	NA	NA
WP_067184791.1\|3145621_3146134_+	hypothetical protein	NA	NA	NA	NA
WP_067184794.1\|3146199_3146934_-	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_067184797.1\|3146930_3147344_-	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_067184799.1\|3147397_3149245_-	strawberry notch C-terminal domain-containing protein	A0A076FMQ0	Aureococcus_anophage	4.8e-14	32.2
WP_067182623.1\|3149294_3150299_-\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	1.0e-10	33.9
WP_067182626.1\|3150295_3151210_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_067182629.1\|3151203_3152751_-\|integrase	tyrosine-type recombinase/integrase	A0A0K2CP59	Brevibacillus_phage	1.9e-11	30.6
WP_009823939.1\|3153307_3154312_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_009823940.1\|3154308_3155664_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_007015824.1\|3155660_3156893_-\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJ76	Virus_Rctr85	2.1e-05	27.3
WP_067184802.1\|3156983_3159200_-	strawberry notch family protein	A0A1Y0T2N3	Pseudomonas_phage	8.6e-10	28.2
WP_067184805.1\|3159241_3160171_-	toprim domain-containing protein	A0A0H5AWB1	Pseudomonas_phage	1.9e-11	29.4
WP_067184808.1\|3160295_3160952_+	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	8.4e-22	50.4
WP_067184810.1\|3161041_3162313_-\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	9.3e-09	21.5
3168863:3168880	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012199

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection