CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014016	Staphylococcus simulans strain FDAARGOS_124 chromosome, complete genome	2 crisprs	csa3,DEDDh,cas3,DinG,cas2,cas1,RT,WYL	0	14	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014016_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014016_1

1194342-1195031

Unclear

Consensus_repeat	Method
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	CRISPRCasFinder
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	CRT
AGTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	PILER-CR

10 spacers

cas2,cas1

The CRISPR arrays of NZ_CP014016_1

>merge|NZ_CP014016|1|1194342-1195031|CRISPRCasFinder,CRT,PILER-CR
TGGTCAATTCATTCTAAAAGATCACAATTCTAAAACCTTTCTAGTGCTAACTTGCGTGTATTATCGTTTTACTTCATTCTAAAAGATCACAATTCTAAAACCAAAAGAACGTATTAATGGAAAACAATTAGTTTTACTTCATTCTAAAAGATCACAATTCTAAAACTAGTGACAACAAAGCGAAAATCGAGATTAGTTTTACTTCATTCTAAAAGATCACAATTCTAAAACAAGTGGGCGACAAGTATTTGAAAATTGCAGTTTTACTTCATTCTAAAAGATCACAATTCTAAAACAAGTGGGCGACAAGTATTTAAAAATTGCAGTTTTACTTCATTCTAAAAGATCACAATTCTAAAACAGCGGTAAACCCGTATTGATTAAAGCAAAGGTTTTACTTCATTCTAAAAGATCACAATTCTAAAACGATGCATCAAATGTTTTTACGCCCAATTCAGTTTTACTTCATTCTAAAAGATCACAATTCTAAAACTGTGACTTACCTAAATCTAACATTTGATATGTTTTACTTCATTCTAAAAAATCACAATTCTAAAACATTACGGAGGATGTCATCGGCTTTCTAACAGTTTTACTTCATTCTAAAAGATCACAATTCTAAAACAAGTTTTGTGTGTTTCATGATACAGGAAAGTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC

>NZ_CP014016|1|1|1194342-1195031|CRISPRCasFinder
TGGTCAATTCATTCTAAAAGATCACAATTCTAAAAC	CTTTCTAGTGCTAACTTGCGTGTATTATC
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	CAAAAGAACGTATTAATGGAAAACAATTA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	TAGTGACAACAAAGCGAAAATCGAGATTA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AAGTGGGCGACAAGTATTTGAAAATTGCA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AAGTGGGCGACAAGTATTTAAAAATTGCA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AGCGGTAAACCCGTATTGATTAAAGCAAAG
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	GATGCATCAAATGTTTTTACGCCCAATTCA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	TGTGACTTACCTAAATCTAACATTTGATAT
GTTTTACTTCATTCTAAAAAATCACAATTCTAAAAC	ATTACGGAGGATGTCATCGGCTTTCTAACA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AAGTTTTGTGTGTTTCATGATACAGGAAA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC

>NZ_CP014016|1|1|1194342-1195031|CRT
TGGTCAATTCATTCTAAAAGATCACAATTCTAAAAC	CTTTCTAGTGCTAACTTGCGTGTATTATC
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	CAAAAGAACGTATTAATGGAAAACAATTA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	TAGTGACAACAAAGCGAAAATCGAGATTA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AAGTGGGCGACAAGTATTTGAAAATTGCA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AAGTGGGCGACAAGTATTTAAAAATTGCA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AGCGGTAAACCCGTATTGATTAAAGCAAAG
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	GATGCATCAAATGTTTTTACGCCCAATTCA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	TGTGACTTACCTAAATCTAACATTTGATAT
GTTTTACTTCATTCTAAAAAATCACAATTCTAAAAC	ATTACGGAGGATGTCATCGGCTTTCTAACA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AAGTTTTGTGTGTTTCATGATACAGGAAA
GTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC

>NZ_CP014016|1|1|1194798-1195031|PILER-CR
AGTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	TGTGACTTACCTAAATCTAACATTTGATA
TGTTTTACTTCATTCTAAAAAATCACAATTCTAAAAC	ATTACGGAGGATGTCATCGGCTTTCTAAC
AGTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC	AAGTTTTGTGTGTTTCATGATACAGGAA
AGTTTTACTTCATTCTAAAAGATCACAATTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014016.2\|WP_105165365.1\|1209543_1210269_-\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|225185
NZ_CP014016.2\|WP_023015755.1\|1182375_1182987_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NZ_CP014016.2\|WP_061054776.1\|1196272_1197148_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP014016.2\|WP_002480619.1\|1188594_1189695_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NZ_CP014016.2\|WP_002480617.1\|1190959_1191868_-\|aspartate-carbamoyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|234849
NZ_CP014016.2\|WP_002480621.1\|1184606_1185371_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	unknown	unknown	gnl\|CDD\|99814
NZ_CP014016.2\|WP_002480608.1\|1201429_1202347_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP014016.2\|WP_061054775.1\|1195081_1195933_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014016.2\|WP_002480607.1\|1202359_1202842_-\|signal-peptidase-II	unknown	unknown	gnl\|CDD\|234739
NZ_CP014016.2\|WP_002480616.1\|1191898_1193200_-\|uracil-xanthine-permease	unknown	unknown	gnl\|CDD\|236744
NZ_CP014016.2\|WP_023015762.1\|1195929_1196223_-\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP014016.2\|WP_002480618.1\|1189701_1190973_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|236479
NZ_CP014016.2\|WP_061054777.1\|1205920_1208668_-\|isoleucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235588
NZ_CP014016.2\|WP_002480605.1\|1203463_1204258_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|225312
NZ_CP014016.2\|WP_002480615.1\|1193421_1193949_-\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	unknown	unknown	gnl\|CDD\|235365
NZ_CP014016.2\|WP_105165375.1\|1202971_1203430_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP014016.2\|WP_002480623.1\|1182988_1183693_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NZ_CP014016.2\|WP_061054774.1\|1185428_1188602_-\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NZ_CP014016.2\|WP_002480622.1\|1183692_1184610_-\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235982
NZ_CP014016.2\|WP_002480602.1\|1208902_1209517_-\|DivIVA-domain-containing-protein	unknown	unknown	gnl\|CDD\|377456

Protein	Function_ID	Function_description	E-value
NZ_CP014016.2\|WP_105165365.1\|1209543_1210269_-\|RNA-binding-protein	gnl\|CDD\|225185	COG2302, COG2302, Uncharacterized conserved protein, contains S4-like domain [Function unknown].	1.19684e-92
NZ_CP014016.2\|WP_023015755.1\|1182375_1182987_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	4.78352e-77
NZ_CP014016.2\|WP_061054776.1\|1196272_1197148_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	3.23461e-92
NZ_CP014016.2\|WP_002480619.1\|1188594_1189695_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NZ_CP014016.2\|WP_002480617.1\|1190959_1191868_-\|aspartate-carbamoyltransferase-catalytic-subunit	gnl\|CDD\|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	1.56537e-169
NZ_CP014016.2\|WP_002480621.1\|1184606_1185371_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	gnl\|CDD\|99814	cd06218, DHOD_e_trans, FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to orotate coupled with the reduction of NAD+. In L. lactis, DHOD B (encoded by pyrDa) is co-expressed with pyrK and both gene products are required for full activity, as well as 3 cofactors: FMN, FAD, and an [2Fe-2S] cluster.	8.92453e-122
NZ_CP014016.2\|WP_002480608.1\|1201429_1202347_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	2.58973e-123
NZ_CP014016.2\|WP_002480607.1\|1202359_1202842_-\|signal-peptidase-II	gnl\|CDD\|234739	PRK00376, lspA, lipoprotein signal peptidase.	1.37287e-51
NZ_CP014016.2\|WP_002480616.1\|1191898_1193200_-\|uracil-xanthine-permease	gnl\|CDD\|236744	PRK10720, PRK10720, uracil transporter; Provisional.	1.09017e-142
NZ_CP014016.2\|WP_023015762.1\|1195929_1196223_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.02755e-26
NZ_CP014016.2\|WP_002480618.1\|1189701_1190973_-\|dihydroorotase	gnl\|CDD\|236479	PRK09357, pyrC, dihydroorotase; Validated.	0
NZ_CP014016.2\|WP_061054777.1\|1205920_1208668_-\|isoleucine--tRNA-ligase	gnl\|CDD\|235588	PRK05743, ileS, isoleucyl-tRNA synthetase; Reviewed.	0
NZ_CP014016.2\|WP_002480605.1\|1203463_1204258_-\|VOC-family-protein	gnl\|CDD\|225312	COG2514, COG2514, Predicted ring-cleavage extradiol dioxygenase [General function prediction only].	4.78216e-79
NZ_CP014016.2\|WP_002480615.1\|1193421_1193949_-\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	gnl\|CDD\|235365	PRK05205, PRK05205, bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR.	2.65186e-88
NZ_CP014016.2\|WP_105165375.1\|1202971_1203430_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	8.49376e-30
NZ_CP014016.2\|WP_002480623.1\|1182988_1183693_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	1.78708e-129
NZ_CP014016.2\|WP_061054774.1\|1185428_1188602_-\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_CP014016.2\|WP_002480622.1\|1183692_1184610_-\|dihydroorotate-dehydrogenase	gnl\|CDD\|235982	PRK07259, PRK07259, dihydroorotate dehydrogenase.	2.37773e-173
NZ_CP014016.2\|WP_002480602.1\|1208902_1209517_-\|DivIVA-domain-containing-protein	gnl\|CDD\|377456	pfam05103, DivIVA, DivIVA protein. The Bacillus subtilis divIVA1 mutation causes misplacement of the septum during cell division, resulting in the formation of small, circular, anucleate mini-cells. Inactivation of divIVA produces a mini-cell phenotype, whereas overproduction of DivIVA results in a filamentation phenotype. These proteins appear to contain coiled-coils.	2.39004e-27

>NZ_CP014016.2|WP_002480615.1|1193421_1193949_-|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR
MTERIVLDDAGMQRTLTRIAHEILEYNKGTENLVLLGVKTRGEFLAKRIQMKIQQIEDVSVPTGTLDITQFRDDLELPTPKMSEKSYVIDVDLKDKVVIIIDDVLYTGRTVRASLDAILLHSRPQKIGLATLVDRGHRELPIRADFVGKNIPTAKDEEVLVYVDETDGRNAVIIE
>NZ_CP014016.2|WP_002480616.1|1191898_1193200_-|uracil-xanthine-permease
MENEQMFERTVKPVLDVNEKPKAGQWAFLSLQHLFAMFGATVLVPFLTGLPISAALLASGIGTLLYILITKSMIPAYLGSSFAFITPIITGLSTHSLGDMLVALFMSGVMYVIIGILIKLSGIGWLMHLLPPVVVGPVIMVIGLSLAPTAANMAMFENTADMKGYNVTYLIVAMITLITTLVVQGYMKGFFSLIPVLIGIIVGYIAGIIFGIVDFKPVMKASWFDWPHIYVPFVDYHPSFHFGLVLLMVPIVFVTVSEHIGHQMVINKIVGRNFFEKPGLHRSIIGDGVSTMFASIIGGPPSTTYGENIGVLAITKIYSIYVIGGAAVIAIILAFVGKFTALISSIPTPVMGGVSILLFGIIASSGLRMLVESKVDFSENRNLVIASVILVVGIGNLMFDIHGVKVEGMALAALSGIVLNLILPKVKPETSNK
>NZ_CP014016.2|WP_002480617.1|1190959_1191868_-|aspartate-carbamoyltransferase-catalytic-subunit
MKQLVSMEHLSNEEIYSLIETAIEYKQGKKVHKLNDTYVANLFFENSTRTKCSFEMAERRLGMQEIPFETSTSSVKKGESLYDTCKTLESIGVDALVIRHPQNDYYKELEGLNIPVINGGDGSGQHPTQSLLDIMTIYEEYKKFKGLNVLICGDIKNSRVARSNYQALTALGANVKFAAPDEWVDDTLDAPYVKIDDVIEETDIVMLLRVQHERHDGELNFDPHEYHEKYGLTKERYNRMKPNAIVMHPAPVNRGVEIDTELVEAPKARIFKQMKNGMFLRMSVISHIIAEQQKGVLIDVAN
>NZ_CP014016.2|WP_002480618.1|1189701_1190973_-|dihydroorotase
MLLIKNAKVLKDGKLTEASILVEDDKVKEIAPEITVGSEVEVIDAKGRFAAPGLVDVHVHLREPGGEHKETIETGTKAAARGGFTTVCPMPNTRPVPDTVEHLEKLNKLIEDNARVRVLPYASITIRQAGSELVDFKGLAEHGAFAFTDDGVGVQTAGTMYEAMQQAAKLNKAVVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICEAVQIARDVLLAEAADCHYHVCHVSTKESVRAIRDAKAAGIKVTAEVTPHHLLMTEDDVPGDNAMYKMNPPLRSKEDRDALIEGLLDGTIDCIATDHAPHAADEKAQPMTKAPFGIVGSETAFPLLYTHFVKNGDWSLQQLVDYLTIKPAQIFDLPYGILEEGKTADLTLIDLEEEREIKAEDFHSKASNTPFIGYKVYGNPVLTMVAGEVAFKEE
>NZ_CP014016.2|WP_002480619.1|1188594_1189695_-|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit
MLEKRYLVFEDGSIYEGRKLGSDNLTKGEIVFNTAMTGYQETISDPSYTGQIITFTYPLIGNYGINRDDFESLVPTLSGVVVKEASTHPSNFRQQKTFNDVLVQYDIPGISGVDTRSITRKIREHGVLKAGFTDHAEDIPAFIEELKQFELSRDEVPMVSTKTPYVSTGSDLSVVLVDFGKKQNIVRELNARGCNVTVVPYNTPAEIILGMSPDGVMLSNGPGDPEDVPEAVEMIQGILGKIPFFGICLGHQLFALSQGAEAFKMKFGHRGANHPVKDLATGKIALTSQNHGYAIDEASVAHTDLEVTHIALNDGTVEGLKHKTLPAFSVQYHPEACPGPTDSNYLFDQFIDMMKEFKAKERTVNA
>NZ_CP014016.2|WP_061054774.1|1185428_1188602_-|carbamoyl-phosphate-synthase-large-subunit
MPRNNDIKTILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYRVILVNSNPATIMTDKEIADKVYIEPLTHDFIARIIRKEQPDALLPTLGGQTGLNMAIQLHDSGVLEANNVRLLGTKLSSIQQAEDRELFRSLMNDLDVPVPESDIVHTVEQAFAFKEQVGYPLIVRPAFTMGGTGGGICHNDEELKEVVTNGLHYSPATQCLIEKSIAGFKEIEYEVMRDKNDNAIVVCNMENIDPVGIHTGDSIVVAPSQTLTDVEYQMLRDVSLKVIRALGIEGGCNVQLALDPYSMNYYIIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMLNPVTGTSYAAFEPALDYVISKIPRFPFDKFEKGERVLGTQMKATGEVMAIGRTYEESLLKAIRSLEYGVHHLGLPNGESYDLDYIKERILQQDDERLFFIGEAIRRGTTLEEIHEMTKIDYFFLNKFQHIIDIERELKAHKGDIEYLKYAKDYGFSDKVIAHRFDMEEEDVYRLRHENDIKPVYKMVDTCAAEFESATPYYYGTYERDNESIVTDKEKVIVLGSGPIRIGQGVEFDYATVHAVWAIQNAGYEAIIVNNNPETVSTDFSISDKLYFEPLTEEDVMNIIELEQPKGVVVQFGGQTAINLAEKLAKHGVQILGTSLENLNRAEDRKEFEELLNTIDVPQPKGKTATSPAEALDNAREIGYSVVVRPSYVLGGRAMEIVYNDAELENYMREAVKASPEHPVLVDRYLTGKEIEVDAISDGETVIIPGIMEHIERAGVHSGDSIAVYPPQTLSDEVIQTLEAYTTKLAKGLDIIGLINIQFVLAHDGVYVLEVNPRSSRTVPFLSKITDIPMAQLAMRAILGEKLSDLGYKPGLQPYSEGVYVKAPVFSFNKLKNVDITLGPEMKSTGEVMGKDLTLEKALFKGLTASGVEVKDHGTVLITVSDKDKEEMVKIAKRLHEVGYKVLATSGTAAKLAENHIPVETVGKIGGEDDLLNRIQNGDVQIVINTMTKGKTIERDGFQIRRASVENGVPCLTSLDTANALTNVIESMTFTMRSM
>NZ_CP014016.2|WP_002480621.1|1184606_1185371_-|dihydroorotate-dehydrogenase-electron-transfer-subunit
MEQNIIVSNREIADRIFEIKVKGPVTRKMTQPGQFVHIKVGEGSLHMLRRPISICHIEPEIETFTMLYRAEGAGTQRLSQMRENDAIDIIAPLGNGFPVEKAERKALLVGGGIGVPPLYELSKQLNRQGIETVHVLGFRSKKDVFYADEFAQLGETHIVTEDGTMGSKGFVTNVISELPVDYDIYYTCGPKPMLKAIKEHDKLADVEGFLSLEERMGCGIGACYACVCHTPESETSYVKVCTDGPVFEKGAVIL
>NZ_CP014016.2|WP_002480622.1|1183692_1184610_-|dihydroorotate-dehydrogenase
MSRLNVEIPGLELKNPIMPASGCFAFGAEFSQFYDLSELGAIMIKAATKEARYGNETPRVAETDSGMINAIGLQNPGVHHIIEHELKKLEQFNVPIIANVAGSTEEDYVYVAEHISKAPNVKALELNISCPNVKEGGMQFGVDPVVAAELTRKVKAVSEVPVYVKLSPNVTDIVAMAKAIAQYADGLTMINTLVGLRIDAKTGRPIIANTVGGLSGPAIKPVAMRMVYQVRQAVDIPIIAMGGVQNAQDVIDYISVGANAVAVGTANFQNPMVCKEIIDELPALLDDLGVNHINELYKRTFEVTK
>NZ_CP014016.2|WP_002480623.1|1182988_1183693_-|orotidine-5'-phosphate-decarboxylase
MANRNLPLPIIALDFATAEEVENFLDLFDEPLYIKIGMELYYQTGPELINKIKARGHQIFLDLKLHDIPNTVKQAMAGLGRLNVDLVNVHAAGGTEMMRQAVEGLRSVNKDTKIIAVTQLTSTTEEMLQKEQNIQTSIEEAVLNYARLTKEAGLDGVVCSPLEAELLTKELGSDFLKVTPGIRPAHYAQDDQKRITTPDKAREMGSTHIVVGRPITQSDNPVESYHHIKESWLG
>NZ_CP014016.2|WP_023015755.1|1182375_1182987_-|orotate-phosphoribosyltransferase
MSKQIAQSLLDIGAVALSPNDLFTWSSGIKSPIYCDNRVTLGYPEVRNAIRDGLIELIQTHFKDAEIVSGTATAGIPHAAFISEKLDMPMSYVRSKSKSHGKQNQIEGAPSKGKKIVVVEDLISTGGSSLVAAEALREAGAEVLGVVAIFTYGLAKADQMFKDADIPFYTLSDYNELIDVAKEQGKISESDIQSLVEWRDNLA
>NZ_CP014016.2|WP_061054775.1|1195081_1195933_-|hypothetical-protein
MKLVGEFYKPIEIVEQKLNVISFQNTSKLNALTDGLIKYSQSKSKNYDENVRLVADNYQTILPNNVNLIIVPCGDINLFDSKIFKEALYHRFEQQIFNEETTNLLYNKVESTIESFLNSLEIKNESYQVDFQSSNIVLKKLLGMFKPDFHNDLDDLNAIEQRKLFIDTLTSTEKENVLVLLFPEAHLGLSDMKAFNKYLQTLNMFSIIVTSHPYFIIESDTLALIKTNGESVNTKQIREELLLFKEKETITDLDKTSKMIAYHEFCQHPYLDDEFFIQFMNKY
>NZ_CP014016.2|WP_023015762.1|1195929_1196223_-|CRISPR-associated-endonuclease-Cas2
MFDLPVETSRERREYRKFVKFLLNEGYVRSQYSIYCKLILNRGTLNHQISKLKQNLPAHGIVQSLIVTEKQFSDMTYLVGEPRTKYDVNTTERILEL
>NZ_CP014016.2|WP_061054776.1|1196272_1197148_-|type-II-CRISPR-associated-endonuclease-Cas1
MSFRTVIITKESKLSLRMNHLIVKADELYKIPLQEILCLVIENPSVSITGHLLNALSENKIITLLCDKKHLPSSFVVPIYGHHKQSRHIAKQLNWNKEYKSLLWQRIIKNKIAKQKQVIQYFYRNIDTSFFDNCVHETKLNDSTNREGLAAKSYFNIILDSGVSRNSDEFVNGGLDYGYQVLLAVFVRTIVSKGYLTEIGIKHKNEFNPFNLACDFMEVFRPMVDFLVLQNVYDKFEKEEKRAILNMFNEKVKLNKKNYFLVNAIEIYLDGIFKFLESGDINFIKMPVFNF
>NZ_CP014016.2|WP_002480608.1|1201429_1202347_-|RluA-family-pseudouridine-synthase
MTQFDFQITEDEHVGQRIDKFLPEQNSDWSRSQIQDWIKEGLVEVNQKVVKANYKMKKNDQVQVTEKETVEADIQPENLDLDIYYEDEDVAIVYKPKGMVVHPSPGHYSGTLVNGLMYQIKDLSGINGEIRPGIVHRIDKDTSGLLMVAKNDIAHRGLVEQLMDKTVTRKYTALVHGNIPHDYGTIDAPIGRNKVDRQAMDVVDDGKDAITHFNVLEHFNNYTLVECELETGRTHQIRVHMKYIGYPLVGDPKYGPKKTMDIGGQALHAGVIGFTHPVTGEYIERKAPLPDYFEEILEDIRTRHA
>NZ_CP014016.2|WP_002480607.1|1202359_1202842_-|signal-peptidase-II
MRKSYFIGATLFVTLAVLILDQFTKAYIVKTMSVGDSYSVIPGFLNITSHRNTGAAWGILSGKMGFFFLVTIIVLGLLTYFYVKEARGHFWMQMAISLLFAGALGNFIDRMKNGEVVDFIDTYIFGYDFPIFNVADSSLTVGVILILILLLFDSKKNKVK
>NZ_CP014016.2|WP_105165375.1|1202971_1203430_-|CHAP-domain-containing-protein
MLVVLGGATYVAVDHQDEIEHYIEQMKPDPMAFNPYDDGECTDYVFEKVKDDGNMIGKSWGDAKYWADKAEEAGYTVNQQPKASSLLQSPRGEEGHVAYIEHVNDDGSLYVTEMNYVAPHKVTSRTIQPQQVQNYHYIHPKENPKTQDTKEA
>NZ_CP014016.2|WP_002480605.1|1203463_1204258_-|VOC-family-protein
MRQLGEKHYVNGVTLNVRDKENLKHFYEEILGFNVINETYTSIQYEVGDSKHRITLHQIDDGREPLVSEAGLFHIGIRLGSHAHLADLMAHLTEHEIPLNGAEHNVSTSLYFTDPEGNGFEFYADQPEETWDFDKENRVIMDTRHLYASKLMNLRSRDGWQGIPDDSMIGNLHLKTVRISEVKDYYLAHFGLEESSFVNKSSLFMSSNGYHHTLAVNHWMSSMQRMENDDTYGLTLVDFHYPETTHTWLKGPDGIAFRFNYLGV
>NZ_CP014016.2|WP_061054777.1|1205920_1208668_-|isoleucine--tRNA-ligase
MNYKETLLMPKTDFPMRGGLPKKEPEIQKQWDEQDLYHKILEKNKGNETYILHDGPPYANGNLHMGHALNKILKDFIVRYKSMQGYYSPYVPGWDTHGLPIEQALTKKGVKRKEMPVSEFRELCKEFALEQIDIQKKDFKRLGVNGDFNDPYITLKPEYEAAQIRLFGEMADRGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSPSIYVAFDVKDGKGVVDEDAKFIIWTTTPWTLPSNVAITVHPELKYGQYKVNGEKYVVGTDLVEEVAEALDWDKDAIELEKTFTGKELEYVETQHPFVDRVSLVINGLHVTTDAGTGAVHTAPGHGEDDYIVGQKYGLPVISPLDDKGVFTEEGGQFEGMFYDKANKAVTDLLKENGSLLKLQFITHSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIEETHFKVDWGKTRIYNMIRDRGEWVISRQRVWGVPLPVFYAENGDIIMDKEVIYHVANLFEKYGSNVWFDREAKDLLPKGFTHPGSPNGEFTKEEDIMDVWFDSGSSHRGVLETRLELSFPADLYLEGSDQYRGWFNSSITTSVATRGQSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQIVKQKGADIARLWVSSVDYLSDVRISDEILKQTADVYRKIRNTLRFMLGNVNDFNPSTDALDEADLLEVDRYLLNRLREFTANIIKHYDNFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEKQDSPKRRSMQTVLYQILVDMTKLLAPILAHTAEEVWSYIPHVEEESVHLANMPEVVEPDTALLEKWNTFMKLRDDVNRALESARNDKVIGKSLEAKVIIGSNEHFDATSFLKDFENLQQLFIVSQVEVEDKVEDGTEYYHGDIKVVHADGEKCERCWNYSTELGSANGLDHLCPRCQAVVETL
>NZ_CP014016.2|WP_002480602.1|1208902_1209517_-|DivIVA-domain-containing-protein
MSFTPNEIKNKEFSRIKNGLEPTEVADYLSQLSQEIEHLKEQKKQLETVVEEKENNLKAYKEVQQSVSDALVQAQSASQETKMAATKEAEAIIAKAKAEADRIVNDGVEKARRLSFQTEDMKRQSKIFRSRFRMLVEAQLDLLKNDDWDYLLNYDLDAQQVTEENFQHLHQNDVTEQEKQQAQAQQAEAQEGTPAQNETDKEQK
>NZ_CP014016.2|WP_105165365.1|1209543_1210269_-|RNA-binding-protein
MLMDKVQQAERNYAPVLTHFLDPRAQYILEVIVNSFDDLQVSFNGGSPSSERKRAVIAPDYFEPTEEDFELVLFDLEYPEKFASIDHRNVLGTLMSFSIERDQLGDIIVGDKIQFILTKNIKSYIMLELKRIKGVPVKLHEVPLEDMIQSKEDWTLHQATVSAMRLDVVLKEMIRKSRSIAKQYIEKKSIKVNHTIIERPDFQLEPGDLLSIQGHGRARVTEIGHKTKKDKLRIVYETLFK

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Crispr_ID: NZ_CP014016_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014016_2

2570472-2571034

Unclear

Consensus_repeat	Method
GTTTTAGTACTCTGTAATTTTAGGTAT	PILER-CR
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	CRISPRCasFinder
GTTTTAGTACTCTGTAATTTTAGGTATNAGTGATTC	CRT

8 spacers

cas2,cas1

The CRISPR arrays of NZ_CP014016_2

>merge|NZ_CP014016|2|2570472-2571034|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTCTGTTTTAAATGCTTCTAAAGAAAGTGCTTTGTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTCATGAACTCAATATCAGTGATAAGCGATTTGTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTCCAAGGTGAGCGTGTTTATCCGAACAAAAAGGTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTCTTGAACATATATGAAAGCTCACTGTAACCCGTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTCTTGTAGCATAACAACAAACTGTGCTCCTAAGTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTCAAAGCAGTATGAATGCAACAACAAAATCCTGTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTCAAAGTAATATCAATACAAATCGTATGGCAAGTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTCATTAAGTTAGGCTTTGCAGATGAGAAATCAGTTTTAGTACTCTGTAATTTTAAGTATGTGTAATTA

>NZ_CP014016|2|2|2570472-2571025|PILER-CR
GTTTTAGTACTCTGTAATTTTAGGTAT	GAGTGATTCTGTTTTAAATGCTTCTAAAGAAAGTGCTTT
GTTTTAGTACTCTGTAATTTTAGGTAT	GAGTGATTCATGAACTCAATATCAGTGATAAGCGATTT
GTTTTAGTACTCTGTAATTTTAGGTAT	GAGTGATTCCAAGGTGAGCGTGTTTATCCGAACAAAAAG
GTTTTAGTACTCTGTAATTTTAGGTAT	GAGTGATTCTTGAACATATATGAAAGCTCACTGTAACCC
GTTTTAGTACTCTGTAATTTTAGGTAT	GAGTGATTCTTGTAGCATAACAACAAACTGTGCTCCTAA
GTTTTAGTACTCTGTAATTTTAGGTAT	AAGTGATTCAAAGCAGTATGAATGCAACAACAAAATCCT
GTTTTAGTACTCTGTAATTTTAGGTAT	AAGTGATTCAAAGTAATATCAATACAAATCGTATGGCAA
GTTTTAGTACTCTGTAATTTTAGGTAT	AAGTGATTCATTAAGTTAGGCTTTGCAGATGAGAAATCA
GTTTTAGTACTCTGTAATTTTAAGTAT

>NZ_CP014016|2|2|2570472-2571034|CRISPRCasFinder
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	TGTTTTAAATGCTTCTAAAGAAAGTGCTTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	ATGAACTCAATATCAGTGATAAGCGATTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	CAAGGTGAGCGTGTTTATCCGAACAAAAAG
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	TTGAACATATATGAAAGCTCACTGTAACCC
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	TTGTAGCATAACAACAAACTGTGCTCCTAA
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTC	AAAGCAGTATGAATGCAACAACAAAATCCT
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTC	AAAGTAATATCAATACAAATCGTATGGCAA
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTC	ATTAAGTTAGGCTTTGCAGATGAGAAATCA
GTTTTAGTACTCTGTAATTTTAAGTATGTGTAATTA

>NZ_CP014016|2|2|2570472-2571034|CRT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	TGTTTTAAATGCTTCTAAAGAAAGTGCTTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	ATGAACTCAATATCAGTGATAAGCGATTT
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	CAAGGTGAGCGTGTTTATCCGAACAAAAAG
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	TTGAACATATATGAAAGCTCACTGTAACCC
GTTTTAGTACTCTGTAATTTTAGGTATGAGTGATTC	TTGTAGCATAACAACAAACTGTGCTCCTAA
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTC	AAAGCAGTATGAATGCAACAACAAAATCCT
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTC	AAAGTAATATCAATACAAATCGTATGGCAA
GTTTTAGTACTCTGTAATTTTAGGTATAAGTGATTC	ATTAAGTTAGGCTTTGCAGATGAGAAATCA
GTTTTAGTACTCTGTAATTTTAAGTATGTGTAATTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014016.2\|WP_002479888.1\|2555976_2557377_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225121
NZ_CP014016.2\|WP_002479872.1\|2579878_2581375_+\|xylulokinase	unknown	unknown	gnl\|CDD\|198374
NZ_CP014016.2\|WP_002479877.1\|2574830_2575838_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NZ_CP014016.2\|WP_061055233.1\|2564353_2564791_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	unknown
NZ_CP014016.2\|WP_061055229.1\|2557393_2558815_+\|glucuronate-isomerase	unknown	unknown	gnl\|CDD\|235087
NZ_CP014016.2\|WP_061055235.1\|2569451_2570441_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014016.2\|WP_057510028.1\|2577662_2578421_+\|5-oxoprolinase-subunit-PxpA	unknown	unknown	gnl\|CDD\|235446
NZ_CP014016.2\|WP_023015517.1\|2558811_2559858_+\|mannonate-dehydratase	unknown	unknown	gnl\|CDD\|235172
NZ_CP014016.2\|WP_002479873.1\|2578424_2579654_+\|divalent-metal-cation-transporter	unknown	unknown	gnl\|CDD\|224826
NZ_CP014016.2\|WP_082732266.1\|2571202_2572291_+\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP014016.2\|WP_037556193.1\|2572545_2573604_+\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP014016.2\|WP_061055232.1\|2562662_2564009_-\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|225723
NZ_CP014016.2\|WP_002479871.1\|2581441_2581621_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014016.2\|WP_002479878.1\|2574109_2574841_+\|5-oxoprolinase-subunit-PxpB	unknown	unknown	gnl\|CDD\|224960
NZ_CP014016.2\|WP_061055231.1\|2560725_2562525_+\|beta-glucuronidase	unknown	unknown	gnl\|CDD\|236657
NZ_CP014016.2\|WP_002479875.1\|2576301_2577666_+\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl\|CDD\|236307
NZ_CP014016.2\|WP_061055230.1\|2559862_2560705_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|236216
NZ_CP014016.2\|WP_060803561.1\|2569132_2569441_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP014016.2\|WP_061055234.1\|2568215_2569121_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP014016.2\|WP_002479876.1\|2575840_2576284_+\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	unknown	unknown	gnl\|CDD\|235777

Protein	Function_ID	Function_description	E-value
NZ_CP014016.2\|WP_002479888.1\|2555976_2557377_+\|MFS-transporter	gnl\|CDD\|225121	COG2211, MelB, Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism].	3.48699e-132
NZ_CP014016.2\|WP_002479872.1\|2579878_2581375_+\|xylulokinase	gnl\|CDD\|198374	cd07808, FGGY_D-XK_EcXK-like, Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases. This subgroup is predominantly composed of bacterial D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17), which catalyze the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. D-xylulose has been used as a source of carbon and energy by a variety of microorganisms. Some uncharacterized sequences are also included in this subgroup. The prototypical member of this CD is Escherichia coli xylulokinase (EcXK), which exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ is required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	0
NZ_CP014016.2\|WP_002479877.1\|2574830_2575838_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	4.28945e-120
NZ_CP014016.2\|WP_061055229.1\|2557393_2558815_+\|glucuronate-isomerase	gnl\|CDD\|235087	PRK02925, PRK02925, glucuronate isomerase; Reviewed.	0
NZ_CP014016.2\|WP_057510028.1\|2577662_2578421_+\|5-oxoprolinase-subunit-PxpA	gnl\|CDD\|235446	PRK05406, PRK05406, 5-oxoprolinase subunit PxpA.	5.91249e-154
NZ_CP014016.2\|WP_023015517.1\|2558811_2559858_+\|mannonate-dehydratase	gnl\|CDD\|235172	PRK03906, PRK03906, mannonate dehydratase; Provisional.	0
NZ_CP014016.2\|WP_002479873.1\|2578424_2579654_+\|divalent-metal-cation-transporter	gnl\|CDD\|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	2.39716e-80
NZ_CP014016.2\|WP_082732266.1\|2571202_2572291_+\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.86615e-96
NZ_CP014016.2\|WP_037556193.1\|2572545_2573604_+\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	2.30293e-87
NZ_CP014016.2\|WP_061055232.1\|2562662_2564009_-\|PepSY-domain-containing-protein	gnl\|CDD\|225723	COG3182, PiuB, Uncharacterized iron-regulated membrane protein [Function unknown].	1.03528e-99
NZ_CP014016.2\|WP_002479878.1\|2574109_2574841_+\|5-oxoprolinase-subunit-PxpB	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	2.85747e-92
NZ_CP014016.2\|WP_061055231.1\|2560725_2562525_+\|beta-glucuronidase	gnl\|CDD\|236657	PRK10150, PRK10150, beta-D-glucuronidase; Provisional.	0
NZ_CP014016.2\|WP_002479875.1\|2576301_2577666_+\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl\|CDD\|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0
NZ_CP014016.2\|WP_061055230.1\|2559862_2560705_+\|SDR-family-oxidoreductase	gnl\|CDD\|236216	PRK08277, PRK08277, D-mannonate oxidoreductase; Provisional.	1.05706e-160
NZ_CP014016.2\|WP_060803561.1\|2569132_2569441_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.62482e-35
NZ_CP014016.2\|WP_061055234.1\|2568215_2569121_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	8.26923e-93
NZ_CP014016.2\|WP_002479876.1\|2575840_2576284_+\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	8.12324e-35

>NZ_CP014016.2|WP_061055235.1|2569451_2570441_+|hypothetical-protein
MYEAVLEISIEELPRVILNTSEYTSIYNEDSTHEEYILETLKNYFQPRNSNKDCVTITNLLECERVSNNRFRGFILNHSAIENEHQLAATSMMTKKIIRELHNDMEIEGYINSINVLLDDLRENLRGTLPLAVKSFDLKQFIRLLSFKYDYTEDYARLINRLEQVVPLVVDEMNYQAKEKAFLIYLYPEAGLSIKEQIRFRKTLNDLPIPIIVLTESSYFLSENIKGLNYFINNIQMITEEFIDDSYWNAPINIEIEKFKERFEYLFKKYCSFLEVNPTISNYNLTEIVVFDDLDLYIVIAFLKHCKFNYHLDIDKEKISSALSAYLFS
>NZ_CP014016.2|WP_060803561.1|2569132_2569441_+|CRISPR-associated-endonuclease-Cas2
MRVMIMFDLPTDTKEERRLYSKFRKGLISEGFLMMQYSIYIKSCINKDSAESSVNYVKRILPPDGHVRALTITEKQYEKMKILLGEEDKNIEILGDNRTILF
>NZ_CP014016.2|WP_061055234.1|2568215_2569121_+|type-II-CRISPR-associated-endonuclease-Cas1
MAWRIVYLSEVDKLALNLNNLKIAKGDLEVKIPLSDIFAIVIEDLTTTITSRLMIELSKYNILVVFCNQQHLPECMVHPINGHFNQYGQMKEQLQWSEQNKGELWKHILVQKIQNQIQCMKHVGVLDERIIKMKELQTLVTSRDEMNIEGQAAKYYFNTFFEDFRRDDEFLIENMVLNFGYTILNSAIARTIVAKGLIPALGIHHIGARNHFNLASDIIEVFRPLVDLYLLKHPPEEEYMTKAYRLELVNLMHARVQIDGKQHTVIRAIEIMVQSIIEYFRTGRYETLKLPNIKQYSFYES
>NZ_CP014016.2|WP_061055233.1|2564353_2564791_+|LPXTG-cell-wall-anchor-domain-containing-protein
MRKIGIFLTTLVAVALIFTGIEDIVKGAEAQAAKAVTGEVVSDELDPDGDGWANIGFENIKLDEPYQTKLVQLTHLKDTGKMSTTEYNEKVAALISEARSIDASQSQELPAAGEAERNLVLVIFGLCISLIGMVTVMTSRKRKSE
>NZ_CP014016.2|WP_061055232.1|2562662_2564009_-|PepSY-domain-containing-protein
MKPKTFNPMQRLHFYAAVFITPLLITLTLSGIAYLFFPEVENQLYKHEFYGQSEHTKQQSMTDAIKQIEKEHPGYTINKVSVMESPYNNRITIGDMEGNSYYIFLDNHNQIVDQQNAKYTYSNMVRSIHSSLSTENTAINYLVELTACWTVFMILSGIYMLVRKKLLKSNNKVLKFQKWHAIVGLIIAIPMLILVFTGLPWSGFMGAKINQISTAYPQLGQTQLVANPPKSEANEIPWALRQKAAPQSEGGGHHGGMAMPMTNIPGQLSLDKVIHNAEKQGLTRPFAIVYPTSPDGSFTLSKASNSGVTGFDVAPEKETTRYMDQYTGKQLGKVDYQDYGILAKWLTWGIPLHEGHLFGMANKIINLLVCIAFLGGIIFGFMSWFRRLKHMKQAEMLPRRVKKPMSISLIITLIILGVLMPLFGFSLIIVFIIETLLYLKDKRNKQLN
>NZ_CP014016.2|WP_061055231.1|2560725_2562525_+|beta-glucuronidase
MLYPITTETRNIIDLNGTWKFRLEHANEKLDATQPLDTDLVMSVPGSYNEQGAISEIRNHVGTVFYERDFIVPKALRDERLVLRFGSATHEAIVYIDGEEVVSHKGGFLPFEVDITDKVGAGSHRLTVSVNNILDHSTLPVGNYEEFTDEDGNLIRKNTPNFDFFNYSGLHRPVKIYTTPHKYVEDITVVPKVEGDNATVRYETEVVGDVEEIRVELLDEEGTIVGSATGAQGDIKVENSRLWEPLNAYLYNLKVTLFDNGEVVDTYTERVGIRSVEVKDGQFLINNKPFYFKGFGKHEDTPINGRGYNENANVMDLNLMKWINANSFRTAHYPYSEEMMRLADEQGIVVIDETTAVGVHLNFLVHLGKSNNPIDTWKDIKTKEAHEQVIRELIARDKNHACVVMWSIANEPESDAKGAKEYFEPLVQLARDLDPQDRPMTIVTIMFSQPDNCQVQDLVDVLCLNRYYGWYVDQGDLRAAKASLKKEMDGWSKVQPNKPIMFTEYGADTVAGLHAIDDIMFTEEYQVKYYEANHEIVDQYPQFIGEQTWNFADFETSTGHIRVQGNRKGIFTRDRKPKSVAFYFKERWANIPDFYYKTK
>NZ_CP014016.2|WP_061055230.1|2559862_2560705_+|SDR-family-oxidoreductase
MIPYEIDLNNKTVVVTGGNGVIGSAMSKSLAQVGANIAIIGLNDETGAQVVREIEEAGGKALFVSASVTDKAQMEQAKTKIHEAFGKVDVLINGAGGNHPKGTTDDEHFDKDNKDQMQTFFELDEASVGFVFDLNFLGTFIPSQVFAQDMIDNKEATIINISSMNAFTPLTKIPAYSGAKAAVSNFTQWLSVYLADTGVRVNAIAPGFLVTSQNEKLLIKEDGSYSARAEKILNATPLHRFGKPEELIGALFFLVDYRSSSFVDGVALPVDGGFNAYSGV
>NZ_CP014016.2|WP_023015517.1|2558811_2559858_+|mannonate-dehydratase
MKMTFRWYGKEDPISLEYIRQIPGMEGIVSAIYDVPVGEVWPLDKIEALKKEIEDAGLELSVIESVPVHEDIKLGRPTRDKYIENYQQTLRNLSKAGIKVVCYNFMPVFDWTRSDLEYRLDDGSTALIYNEDHIKKMDPLSGELSLPGWDSSYTKDDLADLFKAYESVDEEKLWENLSYFINKIIPVAEEEDILMAIHPDDPPWNIFGLPRIITNKENLERFINLYDSKSNGLTMCSGSLGCDKNNDFPEMLRYFGKKDRVHFVHARNIKHTGTHSFEESAHPSDKGSLDMYEIVKAMHDFGYEGPVRPDHGRMIWGETGKPGYGLYDRALGATYLIGLYEAVSKGKE
>NZ_CP014016.2|WP_061055229.1|2557393_2558815_+|glucuronate-isomerase
MAFINETFMLHNDKAVQLYEDYAKDMPIYDYHCHLDPKQISEDHHFDNITDLWLSGDHYKWRVMRAQGIEEHYITGDADKKEKFVKWAQALQNAVGNPVYHWSQLELAMYFGVYDLLTEDNAEEIYERVNQYLKDNHVTTQSLIKESKVNLICTTDNPTDDLHYHDEIKAQSDFKTAVLPAFRPDAAFKIGSQDFLDFVEKLAEITQPIQSVESFIDSLKQRIDYFHSKGGRLADHGLERIDYEDFTSEEITDIFRKALSKETVSDFEKAQFITFVLNELSKAYADKGWTMQIHFGAIRNNNTRAFEKLGPDTGFDSINDQTNLAYNLNHLLDMMEREDHLPKTILYNLNPNYNDVVGSTIANFQTEPGIASKIQHGAGWWFNDTKRGMLRQMSSLADQGMLMHFVGMLTDSRSFISYARHEYFRRILCTYIGEMVENGEIPDEPSLLEKLIKGICYNNAYHYFGLIKEENNQ
>NZ_CP014016.2|WP_002479888.1|2555976_2557377_+|MFS-transporter
METMTKRQEEKVETFKAIEKPKLPLKEKIAYGFGDLGNGMMFDLGQIYLLKFYTDVLGISATYAGLVFLISKIFDAFVDTGVGSYVDSRKNIGPRGKFRPYILFGTVPLAIMTVMTFITPNLDYTGKVIWAFATYMIFSMAYSIVNIPYGSLSASMTVNADDRTQLSVFRNMGSQGALFITGIIVLPMVSQFPNQAIGFPVVVGVLAAIGVIFHIICYKGVKERFTVEPPDTKGQSRIAFKNLLKNGAFAVLAFYTLLTITAMFLKQSTQLYYFQYVLGEVNLVGIVSLFNFIALIPALYLTTVLSKKFGKKMTAIIGVVGFIICEMLNYAFFGENVVTFLIFSTLGMFFLVIPNTVTWAFIADVVEYGQWKSGVRTEGIIYSSYSFTRKVSQALAGFIPGIALTFIGYQPNVEQTADTLQGLGLLYFVVPAVISLIAVIVFGIFYKLTDKRHEQIVKELALREEI
>NZ_CP014016.2|WP_082732266.1|2571202_2572291_+|PTS-transporter-subunit-IIC
MEHTAMDHTSPTHPGTKIGPKYFLFNLLNGVAIGIVAGLIPNAILGEILKALVPFNPVFTQLLHVTTAIQFAVPCLIGALVAYRFKFTPLGIAVVSAASFIGSGAVVFKHNAWVITGIGDLINTMFAAAIASLMILFIGERFGSLNLIILPTFVAVSTGFIALHTLPYVKLVTTAIGNMVNSFTELQPIPMCILISLVYASIVISPISTAALSMAIGIEGLAAGSASIGIAAVEAVLTIGTLRVNRLGVPMTIFLGGVKMMLPNLVRHPIIFLPITTTAAVTGFVASLIGIGGTKESAGFGIIGLVGPINAFRFLDYGDFWLKAILCAVAFFIVPFITAFIAHFVYSKIFKIYDEEIFKFID
>NZ_CP014016.2|WP_037556193.1|2572545_2573604_+|PTS-transporter-subunit-IIC
MTRPGTKVSVGTFFYNVLNGVAFAIIAGLVPHAVLGEILKALSPYSKSAGVLLQVATAIQFTVPMLVGALVAHRFKFTPLGIAVVAAASFIGSGAAQFKNGAWVITGIGDLINTMLAASIASLLILFIGERFGSLNLIILPTFVAVITGFITLHTLPYVKLVTTGIGHIINTFTEMQPVLMCMLIAIAYSMIIISPISTVATSMAIGISGLAAGAASIGITAAEATLVFGTITVNRLGVPATILLGGVKMMLPNMVKYPVMLVPITVTAAISGFVASFIGIGGTKESAGFGIIGMVGPINAFRFMHVDEVWLKLVLIITAFFVVPFTVAYIAHFIFIKIFKLYDKEIFRFLG
>NZ_CP014016.2|WP_002479878.1|2574109_2574841_+|5-oxoprolinase-subunit-PxpB
MDYQIISEQAILVRFEPQIAPETFKKVQQLVVYLERQDHEAIKEIVPSYRAVMIHFDDHKIHAKALIEDLKLDTLDVSDIETSESSKVVRIPVIYGGKYGPDIEEVAKLNDLTVEDVIQLHTEPTYLIYMLGFMPGFPYLGGLDERLYTPRRDEPRVRIDAGSVGIAKNQTGLYPQDSPGGWQIIGRTPLDVFDLDREPMTLYEAGDRIEFYQISQDTYDEIIAQKNDPDFDIERWVTVQDEH
>NZ_CP014016.2|WP_002479877.1|2574830_2575838_+|biotin-dependent-carboxyltransferase-family-protein
MSIRIIKPGLFSTIQDIGRYGYQKEGFSSAGALDRYSYRLGTQLIGNEGPAIEATIIGPTLQFLEDNTVVITGAEFKATLNGEPISHQTVVQVYKGDVLALNAAIKGARGYLHFGHPIDVPEVAGSYATHTRTKMGGFHGRALRKDDMIPVHYNNDYRRHVGYTSDLDLIHEGTDAIRVVEGPQYDSFPDASHEGLVSEPFEISEQSDRMGFRLKGASIPPTDSADIISEPVALGSVQVPNDGNPIVLMNDKQTVGGYTKIATVCQSDLSVLAQKQPGQKVNFEWVTVEEAIQHLDDYNKGFEASLEAIEKEPLFDMREMRTTSKRISELLEGDE
>NZ_CP014016.2|WP_002479876.1|2575840_2576284_+|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein-subunit
MKLEEIKDLINLVKENKVNKFKYKDEAHEIELDFSSPQQTQPATQIQNQATSNPAPEAAQEPQADNQASGETVNAPMVGTFFLQDTKELTEPIVKVGDKIKKGDVIGYIEAMKVMNEVTSEVEGEVTDILVDHGTNVEYDQALIEVK
>NZ_CP014016.2|WP_002479875.1|2576301_2577666_+|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MYRCLIANRGEIAVRIIRACREVGVETVAVYAKGDEKSLHVSLADQAICIGEANPLDSYLNINRIIAAAEITGANAIHPGYGFLSESPNFAQKVEENDIYFIGPTKRTMEMMGDKITARQTVESADVPIIPGSIGAVHSVDEIKEIAKDIGYPVVLKAASGGGGKGIRIVKEPEHLEKAFKEAQSEGKKYFDDDRIYVEAFIPVAKHVEVQVIGDGKENYVHLGERDCSVQRKNQKLIEESPCAALSEEKRQKICEDAVKVAQASNYRSAGTIEFLVTDDAYYFIEMNARIQVEHTVTEMRADRDLLQAQLYLMKHGELPFSQDDIHFTGHVIEARINAENPERKFQPSPGKVKALHLPQGFNVRVDSLLYPGYVVSPYYDSLVAKVIVKGANRTHAIEKLKATLDEMVIDGFSTTADFLYAVLSYPAYADGDAKDVDIKFLDRHQITKGAALT
>NZ_CP014016.2|WP_057510028.1|2577662_2578421_+|5-oxoprolinase-subunit-PxpA
MKIDLNCDLGEAFGNYSFGGDHQIIPLITSANIACGFHAGDENVMYETVKLAKENGVGIGAHPGFHDIQGFGRRNMDLSPDEIYTLVAYQIGALSAFCRIHDVKINHVKPHGALYNMGARDKDIAHAIAQAVYDVDPSLILVGLSNTLLVSEAEAVGLKAANEVFADRRYEENGQLVSRKEADAVLTDTDEAIEQVVKMVKENKVIAKTGKEIELKADTICVHGDGAHALEFVSKIRERLTKEGISITKLGG
>NZ_CP014016.2|WP_002479873.1|2578424_2579654_+|divalent-metal-cation-transporter
MGENKQNKPEFQFTKEHKRLLLGSVFLMATSAIGPAFLTQTAVFTQQFAASFAFAILLSIIIDIGAQINIWRILVVTGLRGQEIANKMVKGLGTFISILVAIGGLAFNIGNVAGAGLGLNAIFGIDVKWGAAITAILAIGVFISKSGQKVMDFVTMILGVMMIGITAYVMVKSNPPYLEAAEKMVMPEHPGALVLPIITLIGGTVGGYITFAGAHRILDSGIKGKDYLPFVNHSAIAGILTTGVMRGLLFLAVLGVVVTGVTLNPENPPASVFEHALGPIGKNIFGIVLFAAALSSVIGSAYTSATFLKTLSKSLMKRSNIIVIVFIVVSTITFLLIGKPVKLLIIAGALNGLILPITLGVILIASKKKSIVGDYKHPTWMLMFGVLAVLVTIVTGFLSFQGLADLWNS
>NZ_CP014016.2|WP_002479872.1|2579878_2581375_+|xylulokinase
MTTEAVIGIDLGTSAIKLIAVDRLGNVLGTQSEPLKLYHDYPGYSEQAPEEWVAAAVNGLHHLLAQPVLSDVSIEGLSFSGQMHGLVIVEQAGQPLRRAILWNDTRTTPQCEQIKAKYGDQVLGNPVVEGFTLTKLLWVQQHEPDLFKQIDTFMLPKDYLRFALTGVLHTEYSDAAATMLLNPQTKAWDKALGASFDIPDHIYPDLVESHAQVGVLKAELQQQLSLNKPVPVFAGGADNACAALGSGVIHPDDAICSIGTSGVLLICEPVGESEGYGHKIHLMNHAVPDVNYLMGVTLSAGYSLSWFKREFYPEDDFTTLMKDAEASQIGAHGLIFTPYLVGERTPHGDASIRGSFIGITGNHTRGDFGRAVVEGITYSLYDSLVYLRSIGRNVTKIVSTGGGAKSDFWLQLQADVFNTEIYKLKHEEGPSMGAAMLAAYSLGWYDSLKDCAEAFIHYSKVFQPDLKRHQTYEAYFEIYQQAYQATRHLTSDLLVLQK
>NZ_CP014016.2|WP_002479871.1|2581441_2581621_-|hypothetical-protein
MSFKEYVEDVVETIKHMRFGSKNGIIMIVSAIVLSAITTPIIGLPLGAWIGYYLEKNGK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	KU598975	Staphylococcus phage CNPx, complete genome	21953-21981	3	0.897
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	DQ831957	Staphylococcus phage CNPH82, complete genome	21944-21972	3	0.897
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	KU598975	Staphylococcus phage CNPx, complete genome	21952-21981	4	0.867
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	DQ831957	Staphylococcus phage CNPH82, complete genome	21943-21972	4	0.867
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	JN192400	Staphylococcus phage vB_SepiS-phiIPLA5, complete genome	22599-22627	4	0.862
NZ_CP014016_1	1.7\|1194769\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194769-1194798	30	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	331219-331248	5	0.833
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	JN192400	Staphylococcus phage vB_SepiS-phiIPLA5, complete genome	22598-22627	5	0.833
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	MK448341	Streptococcus satellite phage Javan16, complete genome	8474-8503	5	0.833
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	KY653120	Staphylococcus phage IME1348_01, complete genome	37544-37572	5	0.828
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	JN192401	Staphylococcus phage vB_SepiS-phiIPLA7, complete genome	21488-21516	5	0.828
NZ_CP014016_1	1.13\|1194967\|28\|NZ_CP014016\|PILER-CR	1194967-1194994	28	NZ_CP011053	Halomonas sp. KO116 plasmid unnamed1, complete sequence	283849-283876	5	0.821
NZ_CP014016_2	2.16\|2570969\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570969-2570998	30	MF417969	Uncultured Caudovirales phage clone 2AX_1, partial genome	9002-9031	5	0.833
NZ_CP014016_2	2.16\|2570969\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570969-2570998	30	MF417907	Uncultured Caudovirales phage clone 7F_7, partial genome	22372-22401	5	0.833
NZ_CP014016_1	1.2\|1194443\|29\|NZ_CP014016\|CRISPRCasFinder,CRT	1194443-1194471	29	NZ_CP011009	Bacillus simplex strain SH-B26 plasmid pSHB26, complete sequence	151544-151572	6	0.793
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	KY653120	Staphylococcus phage IME1348_01, complete genome	37543-37572	6	0.8
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	JN192401	Staphylococcus phage vB_SepiS-phiIPLA7, complete genome	21487-21516	6	0.8
NZ_CP014016_1	1.9\|1194901\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194901-1194930	30	NZ_CP021407	Celeribacter manganoxidans strain DY25 plasmid pDY25-C, complete sequence	58780-58809	6	0.8
NZ_CP014016_1	1.10\|1194967\|29\|NZ_CP014016\|CRISPRCasFinder,CRT	1194967-1194995	29	NZ_CP011053	Halomonas sp. KO116 plasmid unnamed1, complete sequence	283849-283877	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NZ_CP039285	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL2, complete sequence	121391-121419	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NZ_CP043040	Leptospira interrogans serovar Hardjo strain L53 plasmid p1	33956-33984	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NZ_CP044516	Leptospira interrogans serovar Canicola strain 611 plasmid p2, complete sequence	2551-2579	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NC_025197	Leptospira interrogans serovar Canicola strain Gui44 plasmid pGui2, complete sequence	2551-2579	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NZ_CP044512	Leptospira interrogans serovar Canicola strain LJ178 plasmid p2, complete sequence	2551-2579	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NZ_CP039260	Leptospira interrogans strain FMAS_KW1 plasmid pLiLS1, complete sequence	9825-9853	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NZ_CP039286	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence	4083-4111	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NZ_CP039286	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence	82536-82564	6	0.793
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	NC_025151	Leptospira interrogans serovar Lai str. 56601 plasmid Laicp, complete sequence	53448-53476	6	0.793
NZ_CP014016_1	1.12\|1194901\|29\|NZ_CP014016\|PILER-CR	1194901-1194929	29	NZ_CP021407	Celeribacter manganoxidans strain DY25 plasmid pDY25-C, complete sequence	58780-58808	6	0.793
NZ_CP014016_1	1.13\|1194967\|28\|NZ_CP014016\|PILER-CR	1194967-1194994	28	AP019515	Halomonas sulfidaeris ATCC BAA-803 plasmid pBAA-803-A DNA, complete genome	233265-233292	6	0.786
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	MN693421	Marine virus AFVG_25M197, complete genome	16627-16656	6	0.8
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	MN693283	Marine virus AFVG_25M198, complete genome	16672-16701	6	0.8
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	NZ_LR214998	Mycoplasma conjunctivae strain NCTC10147 plasmid 2	7262-7291	6	0.8
NZ_CP014016_2	2.10\|2570574\|29\|NZ_CP014016\|CRISPRCasFinder,CRT	2570574-2570602	29	NZ_CP015232	Epibacterium mobile F1926 plasmid unnamed2, complete sequence	15015-15043	6	0.793
NZ_CP014016_2	2.10\|2570574\|29\|NZ_CP014016\|CRISPRCasFinder,CRT	2570574-2570602	29	NZ_LR027555	Epibacterium mobile isolate EPIB1 plasmid 3, complete sequence	40399-40427	6	0.793
NZ_CP014016_2	2.11\|2570639\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570639-2570668	30	NC_041879	Bacillus phage Mgbh1, complete genome	24430-24459	6	0.8
NZ_CP014016_2	2.16\|2570969\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570969-2570998	30	MH884508	Bacillus phage vB_BcoS-136, complete genome	107882-107911	6	0.8
NZ_CP014016_1	1.3\|1194508\|29\|NZ_CP014016\|CRISPRCasFinder,CRT	1194508-1194536	29	AP018320	Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome	307485-307513	7	0.759
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NZ_CP039285	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL2, complete sequence	121390-121419	7	0.767
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NZ_CP043040	Leptospira interrogans serovar Hardjo strain L53 plasmid p1	33955-33984	7	0.767
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NZ_CP044516	Leptospira interrogans serovar Canicola strain 611 plasmid p2, complete sequence	2550-2579	7	0.767
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NC_025197	Leptospira interrogans serovar Canicola strain Gui44 plasmid pGui2, complete sequence	2550-2579	7	0.767
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NZ_CP044512	Leptospira interrogans serovar Canicola strain LJ178 plasmid p2, complete sequence	2550-2579	7	0.767
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NZ_CP039260	Leptospira interrogans strain FMAS_KW1 plasmid pLiLS1, complete sequence	9824-9853	7	0.767
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NZ_CP039286	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence	4083-4112	7	0.767
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NZ_CP039286	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence	82536-82565	7	0.767
NZ_CP014016_1	1.8\|1194835\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194835-1194864	30	NC_025151	Leptospira interrogans serovar Lai str. 56601 plasmid Laicp, complete sequence	53448-53477	7	0.767
NZ_CP014016_1	1.10\|1194967\|29\|NZ_CP014016\|CRISPRCasFinder,CRT	1194967-1194995	29	AP019515	Halomonas sulfidaeris ATCC BAA-803 plasmid pBAA-803-A DNA, complete genome	233265-233293	7	0.759
NZ_CP014016_1	1.11\|1194835\|29\|NZ_CP014016\|PILER-CR	1194835-1194863	29	MK448341	Streptococcus satellite phage Javan16, complete genome	8475-8503	7	0.759
NZ_CP014016_1	1.12\|1194901\|29\|NZ_CP014016\|PILER-CR	1194901-1194929	29	NZ_CP023039	Komagataeibacter saccharivorans strain CV1 plasmid unnamed3, complete sequence	10350-10378	7	0.759
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	MW057858	Providencia phage PSTCR6, complete genome	12688-12717	7	0.767
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	NC_020909	Octadecabacter arcticus 238 plasmid pOA238_118, complete sequence	15541-15570	7	0.767
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	NC_024208	Lactococcus phage P118, complete genome	28046-28075	7	0.767
NZ_CP014016_1	1.7\|1194769\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194769-1194798	30	NZ_CP016746	Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence	70460-70489	8	0.733
NZ_CP014016_1	1.9\|1194901\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	1194901-1194930	30	NZ_CP023039	Komagataeibacter saccharivorans strain CV1 plasmid unnamed3, complete sequence	10349-10378	8	0.733
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	MN694190	Marine virus AFVG_250M608, complete genome	28251-28280	8	0.733
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	MT446392	UNVERIFIED: Escherichia virus TH15, complete genome	126443-126472	8	0.733
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	NC_028957	Enterobacteria phage vB_EcoM_VR26, complete genome	50089-50118	8	0.733
NZ_CP014016_2	2.15\|2570903\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570903-2570932	30	NZ_LR134427	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 18	15911-15940	8	0.733
NZ_CP014016_2	2.9\|2570508\|30\|NZ_CP014016\|CRISPRCasFinder,CRT	2570508-2570537	30	MK867354	Synechococcus phage S-SCSM1, complete genome	62652-62681	9	0.7

1. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to KU598975 (Staphylococcus phage CNPx, complete genome) position: , mismatch: 3, identity: 0.897

tgtgacttacctaaatctaacatttgata	CRISPR spacer
tgatacttacctaaatccaacatttgata	Protospacer
**  *************.***********

2. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to DQ831957 (Staphylococcus phage CNPH82, complete genome) position: , mismatch: 3, identity: 0.897

tgtgacttacctaaatctaacatttgata	CRISPR spacer
tgatacttacctaaatccaacatttgata	Protospacer
**  *************.***********

3. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to KU598975 (Staphylococcus phage CNPx, complete genome) position: , mismatch: 4, identity: 0.867

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
tgatacttacctaaatccaacatttgatac	Protospacer
**  *************.***********.

4. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to DQ831957 (Staphylococcus phage CNPH82, complete genome) position: , mismatch: 4, identity: 0.867

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
tgatacttacctaaatccaacatttgatac	Protospacer
**  *************.***********.

5. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to JN192400 (Staphylococcus phage vB_SepiS-phiIPLA5, complete genome) position: , mismatch: 4, identity: 0.862

tgtgacttacctaaatctaacatttgata	CRISPR spacer
tgatatttacctaaatctagcatttgata	Protospacer
**  *.*************.*********

6. spacer 1.7|1194769|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 5, identity: 0.833

gatgcatcaaatgtttttacgcccaattca	CRISPR spacer
tttctatcaaatatttttacgcccaattca	Protospacer
  * .*******.*****************

7. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to JN192400 (Staphylococcus phage vB_SepiS-phiIPLA5, complete genome) position: , mismatch: 5, identity: 0.833

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
tgatatttacctaaatctagcatttgataa	Protospacer
**  *.*************.*********

8. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MK448341 (Streptococcus satellite phage Javan16, complete genome) position: , mismatch: 5, identity: 0.833

tgtgacttacctaaatctaaca-tttgatat	CRISPR spacer
tctgacttatctaaatctaacagttcgcta-	Protospacer
* *******.************ **.* **

9. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to KY653120 (Staphylococcus phage IME1348_01, complete genome) position: , mismatch: 5, identity: 0.828

tgtgacttacctaaatctaacatttgata	CRISPR spacer
tgatattttcctaaatctagcatttgata	Protospacer
**  *.** **********.*********

10. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to JN192401 (Staphylococcus phage vB_SepiS-phiIPLA7, complete genome) position: , mismatch: 5, identity: 0.828

tgtgacttacctaaatctaacatttgata	CRISPR spacer
tgatattttcctaaatctagcatttgata	Protospacer
**  *.** **********.*********

11. spacer 1.13|1194967|28|NZ_CP014016|PILER-CR matches to NZ_CP011053 (Halomonas sp. KO116 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.821

aagttttgtgtgtttcatgatacaggaa	CRISPR spacer
gcgttttgtgtatttcatgagacaggag	Protospacer
. *********.******** ******.

12. spacer 2.16|2570969|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MF417969 (Uncultured Caudovirales phage clone 2AX_1, partial genome) position: , mismatch: 5, identity: 0.833

attaagttaggctttgcagatgagaaatca	CRISPR spacer
atcaataaaggttttgcagatgagaaatca	Protospacer
**.**   ***.******************

13. spacer 2.16|2570969|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MF417907 (Uncultured Caudovirales phage clone 7F_7, partial genome) position: , mismatch: 5, identity: 0.833

attaagttaggctttgcagatgagaaatca	CRISPR spacer
atcaataaaggttttgcagatgagaaatca	Protospacer
**.**   ***.******************

14. spacer 1.2|1194443|29|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP011009 (Bacillus simplex strain SH-B26 plasmid pSHB26, complete sequence) position: , mismatch: 6, identity: 0.793

caaaagaacgtattaatggaaaacaatta	CRISPR spacer
ttaaagaaattattaatggaaaacaacaa	Protospacer
. ******  ****************. *

15. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to KY653120 (Staphylococcus phage IME1348_01, complete genome) position: , mismatch: 6, identity: 0.8

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
tgatattttcctaaatctagcatttgatag	Protospacer
**  *.** **********.*********

16. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to JN192401 (Staphylococcus phage vB_SepiS-phiIPLA7, complete genome) position: , mismatch: 6, identity: 0.8

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
tgatattttcctaaatctagcatttgatag	Protospacer
**  *.** **********.*********

17. spacer 1.9|1194901|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP021407 (Celeribacter manganoxidans strain DY25 plasmid pDY25-C, complete sequence) position: , mismatch: 6, identity: 0.8

attacggaggatgtcatcggctttctaaca	CRISPR spacer
ttgacggaggatgtcatcggctgtctccta	Protospacer
 * ******************* ***  .*

18. spacer 1.10|1194967|29|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP011053 (Halomonas sp. KO116 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

aagttttgtgtgtttcatgatacaggaaa	CRISPR spacer
gcgttttgtgtatttcatgagacaggagg	Protospacer
. *********.******** ******..

19. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NZ_CP039285 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL2, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

20. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NZ_CP043040 (Leptospira interrogans serovar Hardjo strain L53 plasmid p1) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

21. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NZ_CP044516 (Leptospira interrogans serovar Canicola strain 611 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

22. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NC_025197 (Leptospira interrogans serovar Canicola strain Gui44 plasmid pGui2, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

23. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NZ_CP044512 (Leptospira interrogans serovar Canicola strain LJ178 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

24. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NZ_CP039260 (Leptospira interrogans strain FMAS_KW1 plasmid pLiLS1, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

25. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NZ_CP039286 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

26. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NZ_CP039286 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

27. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to NC_025151 (Leptospira interrogans serovar Lai str. 56601 plasmid Laicp, complete sequence) position: , mismatch: 6, identity: 0.793

tgtgacttacctaaatctaacatttgata	CRISPR spacer
aatgttttacctaaatctaaaatttgatc	Protospacer
 .** .************** *******

28. spacer 1.12|1194901|29|NZ_CP014016|PILER-CR matches to NZ_CP021407 (Celeribacter manganoxidans strain DY25 plasmid pDY25-C, complete sequence) position: , mismatch: 6, identity: 0.793

attacggaggatgtcatcggctttctaac	CRISPR spacer
ttgacggaggatgtcatcggctgtctcct	Protospacer
 * ******************* ***  .

29. spacer 1.13|1194967|28|NZ_CP014016|PILER-CR matches to AP019515 (Halomonas sulfidaeris ATCC BAA-803 plasmid pBAA-803-A DNA, complete genome) position: , mismatch: 6, identity: 0.786

aagttttgtgtgtttcatgatacaggaa	CRISPR spacer
gcgttttgtgtatttcatgagacaggcg	Protospacer
. *********.******** ***** .

30. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MN693421 (Marine virus AFVG_25M197, complete genome) position: , mismatch: 6, identity: 0.8

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
tactcgaaatgcttctaaagaaattgtttt	Protospacer
*..*. ***************** **.***

31. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MN693283 (Marine virus AFVG_25M198, complete genome) position: , mismatch: 6, identity: 0.8

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
tactcgaaatgcttctaaagaaattgtttt	Protospacer
*..*. ***************** **.***

32. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_LR214998 (Mycoplasma conjunctivae strain NCTC10147 plasmid 2) position: , mismatch: 6, identity: 0.8

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
tgttttaaatgtttctaaagagaaattttt	Protospacer
***********.*********.*.  .***

33. spacer 2.10|2570574|29|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP015232 (Epibacterium mobile F1926 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

atgaactcaatatcagtgataagcgattt	CRISPR spacer
atgaaatcaatatcagtgataaaatataa	Protospacer
***** ****************.  **

34. spacer 2.10|2570574|29|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_LR027555 (Epibacterium mobile isolate EPIB1 plasmid 3, complete sequence) position: , mismatch: 6, identity: 0.793

atgaactcaatatcagtgataagcgattt	CRISPR spacer
atgaaatcaatatcagtgataaaatataa	Protospacer
***** ****************.  **

35. spacer 2.11|2570639|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NC_041879 (Bacillus phage Mgbh1, complete genome) position: , mismatch: 6, identity: 0.8

caaggtgagcgtgtttatccgaacaaaaag	CRISPR spacer
caaggtcagcgagtttatccgaaatgatag	Protospacer
****** **** ***********  .* **

36. spacer 2.16|2570969|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MH884508 (Bacillus phage vB_BcoS-136, complete genome) position: , mismatch: 6, identity: 0.8

attaagttaggctttgcagatgagaaatca	CRISPR spacer
gttaagttaggtgttgcagatgaggtatta	Protospacer
.**********. ***********. **.*

37. spacer 1.3|1194508|29|NZ_CP014016|CRISPRCasFinder,CRT matches to AP018320 (Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome) position: , mismatch: 7, identity: 0.759

tagtgacaacaaagcgaaaatcgagatta	CRISPR spacer
gtgggacaagcaagcgaaaatcgagatcg	Protospacer
  * *****  ****************..

38. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP039285 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL2, complete sequence) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

39. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP043040 (Leptospira interrogans serovar Hardjo strain L53 plasmid p1) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

40. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP044516 (Leptospira interrogans serovar Canicola strain 611 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

41. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NC_025197 (Leptospira interrogans serovar Canicola strain Gui44 plasmid pGui2, complete sequence) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

42. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP044512 (Leptospira interrogans serovar Canicola strain LJ178 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

43. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP039260 (Leptospira interrogans strain FMAS_KW1 plasmid pLiLS1, complete sequence) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

44. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP039286 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

45. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP039286 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL3, complete sequence) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

46. spacer 1.8|1194835|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NC_025151 (Leptospira interrogans serovar Lai str. 56601 plasmid Laicp, complete sequence) position: , mismatch: 7, identity: 0.767

tgtgacttacctaaatctaacatttgatat	CRISPR spacer
aatgttttacctaaatctaaaatttgatcc	Protospacer
 .** .************** ******* .

47. spacer 1.10|1194967|29|NZ_CP014016|CRISPRCasFinder,CRT matches to AP019515 (Halomonas sulfidaeris ATCC BAA-803 plasmid pBAA-803-A DNA, complete genome) position: , mismatch: 7, identity: 0.759

aagttttgtgtgtttcatgatacaggaaa	CRISPR spacer
gcgttttgtgtatttcatgagacaggcgg	Protospacer
. *********.******** ***** ..

48. spacer 1.11|1194835|29|NZ_CP014016|PILER-CR matches to MK448341 (Streptococcus satellite phage Javan16, complete genome) position: , mismatch: 7, identity: 0.759

tgtgacttacctaaatctaacatttgata	CRISPR spacer
tctgacttatctaaatctaacagttcgct	Protospacer
* *******.************ ** ..

49. spacer 1.12|1194901|29|NZ_CP014016|PILER-CR matches to NZ_CP023039 (Komagataeibacter saccharivorans strain CV1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

attac-ggaggatgtcatcggctttctaac	CRISPR spacer
-cgacaggaggatgtcatcgcctttcttcg	Protospacer
 . ** ************** ******

50. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MW057858 (Providencia phage PSTCR6, complete genome) position: , mismatch: 7, identity: 0.767

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
tgttttacatgctcctaaagaaatggtcgt	Protospacer
******* *****.*********  *.. *

51. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NC_020909 (Octadecabacter arcticus 238 plasmid pOA238_118, complete sequence) position: , mismatch: 7, identity: 0.767

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
agttttaaatgcttctaaacaacttggcat	Protospacer
 ****************** **  ** . *

52. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NC_024208 (Lactococcus phage P118, complete genome) position: , mismatch: 7, identity: 0.767

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
gtttttaaatgtttctaaagaaataccttg	Protospacer
  *********.***********   ***

53. spacer 1.7|1194769|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP016746 (Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence) position: , mismatch: 8, identity: 0.733

gatgcatcaaatgtttttacgcccaattca	CRISPR spacer
ataaaataaaatgtttttacgctcaattga	Protospacer
.  . ** **************.***** *

54. spacer 1.9|1194901|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_CP023039 (Komagataeibacter saccharivorans strain CV1 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

attac-ggaggatgtcatcggctttctaaca	CRISPR spacer
-cgacaggaggatgtcatcgcctttcttcgg	Protospacer
 . ** ************** ******   .

55. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MN694190 (Marine virus AFVG_250M608, complete genome) position: , mismatch: 8, identity: 0.733

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
ttttttaaattcttctaaagaaatccaatg	Protospacer
* ******** ************ .   *

56. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MT446392 (UNVERIFIED: Escherichia virus TH15, complete genome) position: , mismatch: 8, identity: 0.733

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
tgatttaaatggttctaaagaaaaattagt	Protospacer
** ******** ***********.  .  *

57. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NC_028957 (Enterobacteria phage vB_EcoM_VR26, complete genome) position: , mismatch: 8, identity: 0.733

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
tgatttaaatggttctaaagaaaaattagt	Protospacer
** ******** ***********.  .  *

58. spacer 2.15|2570903|30|NZ_CP014016|CRISPRCasFinder,CRT matches to NZ_LR134427 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 18) position: , mismatch: 8, identity: 0.733

aaagtaatatcaatacaaatcgtatggcaa	CRISPR spacer
ccattaatatcaatacaattcctatggacg	Protospacer
  * ************** ** *****  .

59. spacer 2.9|2570508|30|NZ_CP014016|CRISPRCasFinder,CRT matches to MK867354 (Synechococcus phage S-SCSM1, complete genome) position: , mismatch: 9, identity: 0.7

tgttttaaatgcttctaaagaaagtgcttt	CRISPR spacer
aaaattaaatgcttataaagaaagtcttga	Protospacer
 .  ********** ********** .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

19541 : 49185

Enterobacteria_phage(33.33%)

protease,holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002479791.1\|19541_21641_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	1.0e-113	37.2
WP_002479790.1\|21803_22490_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002479789.1\|22502_24038_+	gluconokinase	NA	NA	NA	NA
WP_061054600.1\|24174_25536_+	gluconate permease	NA	NA	NA	NA
WP_002479787.1\|25606_26386_+	hypothetical protein	NA	NA	NA	NA
WP_061054601.1\|26430_27684_+	acetylornithine deacetylase	NA	NA	NA	NA
WP_002479785.1\|27780_29949_-	RNA degradosome polyphosphate kinase	NA	NA	NA	NA
WP_037556180.1\|30155_31685_-	exopolyphosphatase	NA	NA	NA	NA
WP_002479783.1\|32030_32492_+	DUF1307 domain-containing protein	NA	NA	NA	NA
WP_105165370.1\|32741_33464_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_061054602.1\|33652_34396_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002479780.1\|34564_35233_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	5.2e-19	34.2
WP_002479779.1\|35229_36009_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002479778.1\|36180_37344_+	MFS transporter	NA	NA	NA	NA
WP_037556068.1\|37382_38762_-	carboxylesterase/lipase family protein	NA	NA	NA	NA
WP_002479776.1\|38844_40482_-	APC family permease	NA	NA	NA	NA
WP_061054603.1\|40958_41555_+	YdeI/OmpD-associated family protein	NA	NA	NA	NA
WP_002479773.1\|42022_43237_+\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	3.8e-20	50.5
WP_002479772.1\|43236_43866_+	ABC transporter permease	NA	NA	NA	NA
WP_002479771.1\|43897_44842_+	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002479770.1\|44841_45531_+	ABC transporter permease	NA	NA	NA	NA
WP_002479769.1\|45624_46392_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002479768.1\|46505_47048_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002479767.1\|47049_47412_-	DUF3147 family protein	NA	NA	NA	NA
WP_002479766.1\|47431_47791_-	DUF3147 family protein	NA	NA	NA	NA
WP_002479765.1\|48025_48727_-\|holin	antiholin-like protein LrgB	NA	NA	NA	NA
WP_002479764.1\|48723_49185_-\|holin	antiholin-like murein hydrolase modulator LrgA	NA	NA	NA	NA

DBSCAN-SWA_2

568717 : 603082

Staphylococcus_phage(92.59%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096754676.1\|568717_570679_-	copper-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.8e-67	30.3
WP_103364072.1\|571020_571512_-	hypothetical protein	NA	NA	NA	NA
WP_002481263.1\|571712_572405_+	hypothetical protein	NA	NA	NA	NA
WP_002481262.1\|572520_573909_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.8e-157	56.9
WP_002481261.1\|573911_574922_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	8.5e-98	54.0
WP_002481260.1\|574912_575170_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	4.7e-29	75.7
WP_002481259.1\|575247_575739_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.0e-35	50.3
WP_002481258.1\|575704_576478_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.7e-93	66.5
WP_002481257.1\|576530_578123_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	4.0e-259	81.4
WP_002481256.1\|578509_579706_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	8.8e-187	81.4
WP_002481255.1\|579802_580702_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	4.0e-99	75.4
WP_002481254.1\|580823_581660_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.2e-103	64.1
WP_002481253.1\|581711_582065_-	CrcB family protein	NA	NA	NA	NA
WP_061054676.1\|582057_582429_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	5.2e-37	63.6
WP_002481251.1\|582489_582798_-	hypothetical protein	NA	NA	NA	NA
WP_002481250.1\|582985_583702_+	transaldolase	M1PR54	Cyanophage	3.8e-20	35.0
WP_002481249.1\|583843_584305_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.8e-18	40.9
WP_002481248.1\|584279_584720_-	hypothetical protein	NA	NA	NA	NA
WP_002481247.1\|584719_585217_-	hypothetical protein	A0A2H4PQT5	Staphylococcus_phage	1.1e-21	42.5
WP_023016000.1\|585421_585643_+	hypothetical protein	NA	NA	NA	NA
WP_002481245.1\|586042_586888_+	N-acetylglucosaminidase	A0A1W6JNR1	Staphylococcus_phage	4.2e-42	41.7
WP_002481244.1\|587029_588511_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.0e-14	64.5
WP_002481243.1\|588904_589954_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	9.0e-119	59.6
WP_002481242.1\|589958_590591_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.7e-67	61.4
WP_002481241.1\|590606_591788_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.8e-168	73.5
WP_002481240.1\|591820_592282_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.1e-57	72.5
WP_002481239.1\|592355_593351_-	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	2.9e-114	63.3
WP_002481238.1\|593612_594443_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002481237.1\|594619_595576_+	L-lactate dehydrogenase	NA	NA	NA	NA
WP_002481236.1\|595641_596199_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	6.0e-61	62.2
WP_002481235.1\|596195_597158_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.5e-67	84.4
WP_061054677.1\|597430_598609_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	6.7e-163	73.2
WP_002481232.1\|598987_601402_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	84.9
WP_002481231.1\|601422_601740_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.5e-32	66.7
WP_061054678.1\|601825_603082_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	2.6e-40	75.0

DBSCAN-SWA_3

726337 : 736411

Klosneuvirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061054696.1\|726337_728611_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.7e-75	30.7
WP_023016066.1\|728629_729148_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	8.1e-28	44.4
WP_002481117.1\|729499_731689_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	9.0e-12	38.0
WP_002481116.1\|731704_732157_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_002481115.1\|732153_733029_+	N-acetylmuramoyl-L-alanine amidase	A0A0N9SGH1	Paenibacillus_phage	6.8e-11	33.1
WP_002481114.1\|733354_734629_+\|tRNA	histidine--tRNA ligase	A0A2K9L6G5	Tupanvirus	3.9e-15	23.8
WP_061054697.1\|734644_736411_+\|tRNA	aspartate--tRNA ligase	A0A1V0SIS0	Klosneuvirus	9.2e-07	33.7

DBSCAN-SWA_4

1308080 : 1316502

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002480502.1\|1308080_1308647_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.5e-32	40.3
WP_061054794.1\|1308643_1309684_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.5e-68	43.5
WP_002480500.1\|1309688_1311110_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.6e-47	30.8
WP_002480499.1\|1311088_1313278_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	7.4e-139	39.4
WP_002480498.1\|1313270_1313942_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002480497.1\|1313941_1314202_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002480496.1\|1314201_1314906_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	1.1e-48	42.9
WP_002480495.1\|1314905_1316033_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002480494.1\|1316019_1316502_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	4.7e-22	44.7

DBSCAN-SWA_5

1518767 : 1578468

Staphylococcus_phage(55.26%)

tail,protease,integrase,portal,transposase,terminase,capsid,head

attL 1562669:1562683|attR 1584139:1584153

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002481612.1\|1518767_1519526_-	Fe-S cluster assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	1.8e-07	28.3
WP_061054819.1\|1520283_1520874_-	hypothetical protein	NA	NA	NA	NA
WP_002481609.1\|1521358_1521829_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	4.4e-41	53.6
WP_061054820.1\|1521888_1522524_-	hypothetical protein	Q4ZE82	Staphylococcus_phage	4.8e-22	29.7
WP_061054821.1\|1522520_1523039_-	hypothetical protein	NA	NA	NA	NA
WP_061054822.1\|1523051_1523375_-	hypothetical protein	A0A2H4JHK4	uncultured_Caudovirales_phage	1.2e-10	36.5
WP_061055253.1\|1523689_1524322_-	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	3.9e-85	70.8
WP_061054823.1\|1525004_1526660_-	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	1.1e-131	42.5
WP_061054824.1\|1526664_1527522_-	primase alpha helix C-terminal domain-containing protein	A0A2H4JEH3	uncultured_Caudovirales_phage	3.2e-90	55.7
WP_061054825.1\|1527607_1527901_-	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	2.7e-20	52.8
WP_061054826.1\|1527901_1528312_-	hypothetical protein	A0A2H4JBF1	uncultured_Caudovirales_phage	1.8e-59	85.8
WP_061054827.1\|1528313_1528517_-	hypothetical protein	A0A2H4JD47	uncultured_Caudovirales_phage	2.9e-18	69.8
WP_061054828.1\|1528535_1528808_-	hypothetical protein	Q4ZE77	Staphylococcus_phage	5.7e-25	57.8
WP_061055254.1\|1528773_1529019_-	helix-turn-helix transcriptional regulator	Q4ZE78	Staphylococcus_phage	8.8e-17	58.8
WP_061054829.1\|1529201_1529759_+	helix-turn-helix transcriptional regulator	A0A0E3U244	Fusobacterium_phage	1.3e-07	49.2
WP_061054830.1\|1529774_1530998_+\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	6.2e-103	49.5
WP_002481595.1\|1531140_1531968_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002481594.1\|1531992_1532688_-	ABC transporter permease	NA	NA	NA	NA
WP_061054831.1\|1532680_1533706_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.1e-27	37.4
WP_002481592.1\|1533968_1534265_-	thioredoxin family protein	NA	NA	NA	NA
WP_002481591.1\|1534261_1534624_-	hypothetical protein	NA	NA	NA	NA
WP_002481590.1\|1534915_1535296_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_002481589.1\|1535450_1535807_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.9e-22	47.7
WP_002481588.1\|1535949_1536270_+	thioredoxin family protein	A0A1X9I9P5	Staphylococcus_phage	8.3e-07	36.4
WP_002481587.1\|1536338_1536881_-	nitroreductase	NA	NA	NA	NA
WP_002481586.1\|1536954_1537680_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	3.1e-09	27.9
WP_002481585.1\|1538087_1538603_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002480485.1\|1538758_1540075_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	4.7e-40	29.6
WP_023015356.1\|1540313_1540517_-	sterile alpha motif-like domain-containing protein	NA	NA	NA	NA
WP_061054832.1\|1540985_1541843_-	TPM domain-containing protein	NA	NA	NA	NA
WP_002481583.1\|1541839_1542421_-	LemA family protein	NA	NA	NA	NA
WP_002481582.1\|1542638_1543943_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_002481581.1\|1544061_1544808_+	hypothetical protein	A0A2H4J494	uncultured_Caudovirales_phage	7.6e-19	77.8
WP_002481579.1\|1544882_1545086_-	cold-shock protein	Q9AZD3	Lactococcus_phage	4.1e-20	67.7
WP_002481578.1\|1545448_1546261_+	oxidoreductase	NA	NA	NA	NA
WP_061055255.1\|1546329_1546944_-	flavin reductase family protein	NA	NA	NA	NA
WP_002481576.1\|1547380_1548070_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	9.4e-16	38.6
WP_002481575.1\|1548681_1549152_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	3.2e-68	84.9
WP_002481574.1\|1549215_1551579_-	ribonuclease R	Q0GXV6	Lactococcus_phage	2.3e-93	39.5
WP_002481573.1\|1551622_1552363_-	carboxylesterase	NA	NA	NA	NA
WP_002481572.1\|1552456_1552693_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_002481571.1\|1552781_1553249_-	hypothetical protein	NA	NA	NA	NA
WP_002481570.1\|1553441_1554746_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	4.5e-192	78.7
WP_002481569.1\|1554839_1556357_-	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_002481568.1\|1556358_1557120_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_002481567.1\|1557159_1558350_-	phosphoglycerate kinase	NA	NA	NA	NA
WP_002481566.1\|1558616_1559624_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_002481565.1\|1559677_1560703_-	hypothetical protein	NA	NA	NA	NA
WP_002481564.1\|1561006_1561231_+	hypothetical protein	NA	NA	NA	NA
WP_061054833.1\|1561275_1562064_-	DUF4887 domain-containing protein	NA	NA	NA	NA
WP_002481562.1\|1562647_1563550_+	TIGR01777 family protein	NA	NA	NA	NA
1562669:1562683	attL	NA	NA	NA	NA
WP_002481561.1\|1563899_1564484_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	4.8e-53	55.8
WP_061054834.1\|1565341_1565701_-	hypothetical protein	NA	NA	NA	NA
WP_060804156.1\|1565782_1566091_-\|head	phage head closure protein	NA	NA	NA	NA
WP_061054835.1\|1566150_1567794_-\|terminase	terminase large subunit	A0A290GJW3	Caldibacillus_phage	6.5e-156	50.3
WP_060804154.1\|1567786_1568107_-	hypothetical protein	NA	NA	NA	NA
WP_061054837.1\|1568526_1568808_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_061054838.1\|1568873_1570106_-\|capsid	phage major capsid protein	NA	NA	NA	NA
WP_061054839.1\|1570107_1570674_-\|head,protease	HK97 family phage prohead protease	U3PDW7	Staphylococcus_phage	2.7e-21	37.1
WP_061054840.1\|1570660_1571863_-\|portal	phage portal protein	A0A1L2BY94	Clostridium_phage	1.7e-60	34.9
WP_061054841.1\|1572032_1572305_-	hypothetical protein	Q4ZE68	Staphylococcus_phage	1.2e-30	70.8
WP_061054842.1\|1572291_1573095_-	bifunctional DNA primase/polymerase	Q4ZE69	Staphylococcus_phage	3.7e-120	76.8
WP_061054843.1\|1573264_1574884_-	hypothetical protein	A0A1W6JPF4	Staphylococcus_phage	1.0e-230	74.1
WP_061054844.1\|1574941_1575241_-	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	6.1e-20	48.5
WP_061054845.1\|1575237_1575582_-	hypothetical protein	NA	NA	NA	NA
WP_061054846.1\|1575586_1575793_-	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	5.1e-18	63.1
WP_061054847.1\|1575795_1575999_-	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	7.5e-22	68.7
WP_061054848.1\|1576015_1576261_-	DUF771 domain-containing protein	NA	NA	NA	NA
WP_061054849.1\|1576305_1576533_-	helix-turn-helix transcriptional regulator	A0A1Q1PVY0	Staphylococcus_phage	1.9e-10	47.9
WP_105165378.1\|1576652_1577411_+	helix-turn-helix transcriptional regulator	A0A1Q1PVX8	Staphylococcus_phage	1.2e-06	37.5
WP_061054851.1\|1577412_1578468_+\|integrase	site-specific integrase	A0A1W6JQE7	Staphylococcus_phage	5.8e-65	43.1
1584139:1584153	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1619277 : 1631758

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172954254.1\|1619277_1620234_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	1.3e-132	80.1
WP_002481524.1\|1620551_1621526_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	2.1e-170	90.7
WP_002481523.1\|1621638_1623744_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	88.0
WP_023015387.1\|1623706_1624108_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.8e-43	65.4
WP_002481521.1\|1624992_1625880_+	DMT family transporter	NA	NA	NA	NA
WP_002481520.1\|1625882_1626386_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	6.6e-51	70.1
WP_002481519.1\|1626568_1628092_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	7.1e-72	37.7
WP_002481518.1\|1628386_1629889_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	3.0e-67	34.3
WP_002481517.1\|1630015_1630552_-	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_002481516.1\|1630693_1631758_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	2.2e-19	25.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP014016

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection