CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014485	Streptomyces albidoflavus strain SM254 chromosome, complete genome	38 crisprs	csa3,DEDDh,cas3,DinG,Cas14u_CAS-V,WYL,c2c9_V-U4,Cas9_archaeal,cas4	8	41	1	0

1. NZ_CP014485

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014485_1

• CRISPR_ID: NZ_CP014485_1
• CRISPR_location: 385369-385471
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_1

Consensus_repeat	Method
AGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP014485_1

>1.1|385392|57|NZ_CP014485|CRISPRCasFinder
ATCGGTGACCCGCAGGGGCACGGCCGGTAGGTCGGGGCGAAGCCCGGCACACACAAC

CRISPR arrays and Neighbor proteins around NZ_CP014485_1

CRISPR arrays

The CRISPR arrays of NZ_CP014485_1

>merge|NZ_CP014485|1|385369-385471|CRISPRCasFinder
AGCCCGGCCGGCGCTTGAGGCCAATCGGTGACCCGCAGGGGCACGGCCGGTAGGTCGGGGCGAAGCCCGGCACACACAACAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP014485|1|1|385369-385471|CRISPRCasFinder
AGCCCGGCCGGCGCTTGAGGCCA	ATCGGTGACCCGCAGGGGCACGGCCGGTAGGTCGGGGCGAAGCCCGGCACACACAAC
AGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061403780.1|384472_385150_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014485.1|WP_010640359.1|396378_396963_-|flavin-reductase-family-protein	unknown	unknown	gnl|CDD|214900
NZ_CP014485.1|WP_015506693.1|390556_391528_-|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP014485.1|WP_061403779.1|383498_384476_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP014485.1|WP_061403777.1|376160_377297_-|PLP-dependent-cysteine-synthase-family-protein	unknown	unknown	gnl|CDD|223110
NZ_CP014485.1|WP_003952271.1|385541_386765_-|geranylgeranyl-reductase-family-protein	unknown	unknown	gnl|CDD|273936
NZ_CP014485.1|WP_061403783.1|391784_392825_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP014485.1|WP_008416220.1|375342_376149_+|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl|CDD|224268
NZ_CP014485.1|WP_061403782.1|388340_389321_-|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|107205
NZ_CP014485.1|WP_061403781.1|386925_388293_+|dipeptidase	unknown	unknown	gnl|CDD|236127
NZ_CP014485.1|WP_003952263.1|395391_396177_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl|CDD|238847
NZ_CP014485.1|WP_061403778.1|382498_383158_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_010640320.1|378813_380052_-|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP014485.1|WP_003952265.1|392850_394152_-|aldolase	unknown	unknown	gnl|CDD|367449
NZ_CP014485.1|WP_010640322.1|380103_380763_-|alpha-ketoglutarate-dependent-dioxygenase-AlkB	unknown	unknown	gnl|CDD|372627
NZ_CP014485.1|WP_049978269.1|394335_395298_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl|CDD|224936
NZ_CP014485.1|WP_003952279.1|377621_377942_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_015506691.1|380894_382112_+|MFS-transporter	unknown	unknown	gnl|CDD|340951
NZ_CP014485.1|WP_003952268.1|389331_390354_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239217
NZ_CP014485.1|WP_008416226.1|378188_378725_+|ATP-binding-protein	unknown	unknown	gnl|CDD|340413

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_061403780.1|384472_385150_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.97501e-66
NZ_CP014485.1|WP_015506693.1|390556_391528_-|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	8.78902e-63
NZ_CP014485.1|WP_061403779.1|383498_384476_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	5.11962e-27
NZ_CP014485.1|WP_061403777.1|376160_377297_-|PLP-dependent-cysteine-synthase-family-protein	gnl|CDD|223110	COG0031, CysK, Cysteine synthase [Amino acid transport and metabolism].	1.21922e-94
NZ_CP014485.1|WP_003952271.1|385541_386765_-|geranylgeranyl-reductase-family-protein	gnl|CDD|273936	TIGR02032, Uncharacterized_protein_MJ1520, geranylgeranyl reductase family. This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll].	9.56591e-91
NZ_CP014485.1|WP_061403783.1|391784_392825_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.26372e-102
NZ_CP014485.1|WP_008416220.1|375342_376149_+|DeoR/GlpR-transcriptional-regulator	gnl|CDD|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	1.48224e-77
NZ_CP014485.1|WP_061403782.1|388340_389321_-|pyridoxal-phosphate-dependent-enzyme	gnl|CDD|107205	cd01562, Thr-dehyd, Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.	2.56034e-73
NZ_CP014485.1|WP_061403781.1|386925_388293_+|dipeptidase	gnl|CDD|236127	PRK07907, PRK07907, hypothetical protein; Provisional.	0
NZ_CP014485.1|WP_003952263.1|395391_396177_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl|CDD|238847	cd01714, ETF_beta, The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an alpha and a beta subunit which binds one molecule of FAD per dimer . A similar system also exists in some bacteria. The homologous pair of proteins (FixA/FixB) are essential for nitrogen fixation. The beta subunit protein is distantly related to and forms a heterodimer with the alpha subunit.	4.84728e-79
NZ_CP014485.1|WP_003952265.1|392850_394152_-|aldolase	gnl|CDD|367449	pfam03328, HpcH_HpaI, HpcH/HpaI aldolase/citrate lyase family. This family includes 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase and 4-hydroxy-2-oxovalerate aldolase.	0.00440912
NZ_CP014485.1|WP_010640320.1|378813_380052_-|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.38013e-38
NZ_CP014485.1|WP_010640359.1|396378_396963_-|flavin-reductase-family-protein	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	3.87679e-45
NZ_CP014485.1|WP_010640322.1|380103_380763_-|alpha-ketoglutarate-dependent-dioxygenase-AlkB	gnl|CDD|372627	pfam13532, 2OG-FeII_Oxy_2, 2OG-Fe(II) oxygenase superfamily.	1.33204e-57
NZ_CP014485.1|WP_049978269.1|394335_395298_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl|CDD|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	2.47113e-103
NZ_CP014485.1|WP_015506691.1|380894_382112_+|MFS-transporter	gnl|CDD|340951	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters. The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.24595e-81
NZ_CP014485.1|WP_003952268.1|389331_390354_-|NUDIX-hydrolase	gnl|CDD|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	7.14438e-17
NZ_CP014485.1|WP_008416226.1|378188_378725_+|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	9.97847e-17

Protein sequences

>NZ_CP014485.1|WP_061403780.1|384472_385150_+|response-regulator-transcription-factor
MTTRLGPTRILIADDQEDVRSGFRLILGSQPDMSVVGEAADGLTAVDLARALRPDLVLADIRMPGVDGLELTRRLAGPGVPDPIRVLVVTTFDHDSYVRTALHDGACGFLLKRSGPGLLIEGVRAAMAGDILISPQLTVRLLQTLTPSAPAPPTRLAPLTARETEIARLVAQGHTNAEIGTTLSISPGTAKTHIANIQTKLKARNRVGIAAWTWENGLANPTPQN
>NZ_CP014485.1|WP_061403779.1|383498_384476_+|sensor-histidine-kinase
MFCAVLSLVTSFVLPTAGSGGGWKLAEVAVLLVLLGVVSRWSPLRELVVAVPLMALAVALWPLPLVAGESFPEAVGIATFWLLPAVAAVGAGAYPRRQERRRRSAVAEARSAQRLQLSRDLHDFVAHDVSGIVVQAQAARFVATTDPSQAVLALERIERAGLNALAAMDRTVQMLHGPEVAPATDPLPGVSQLPSLIEDFTSAGAAEAHLDLPPQVSTGLSREVGSVAYRIVVEALTNVRRHAPDASRVTVAFTPTASAVELRITDDGKARSAPARRRASRGGLGLPALAEHAQAVGGTLSAGPHGDGGWQLTAVLPATLPEETP
>NZ_CP014485.1|WP_061403778.1|382498_383158_-|hypothetical-protein
MRITTIGATATAVAVLASPITSTPAPTPATVPAVPAASVVSKPAKAASVHGEARISYIESIHDDIRFTIHAEQTPFTRPMPPTAPEGLSTDARGTLKFSHSRGEVTGWAEATVDCLVTSGRTATLTAVVTKSNVEEPGARLGISVQQGGKGEPDRLGFSWGVVNVDPENIDENGQLVRPQAGSCMAPAPFTTVIKGGYKVIHAEITKSPTQPEPAPHHS
>NZ_CP014485.1|WP_015506691.1|380894_382112_+|MFS-transporter
MPLINKPGSTPRSASSPSSSRSSLSVLRRALTVFFALDGFVFAGWVVRIPAIKEQTQASASDLGLALLGVSAGAVVTMTLTGRLCRRYGSRPVTVAGALLLALGVTLPPLTHSALALGLVLLVFGAAYGGINVAMNSAAVDVVAALGRPVMPTFHAAFSLGGMVGAGLGGIVAGYLSPTWHLLLLGVVTLLVTLATAPVLLRQPMPAPVRPEPAEGASAAPLAGRARTLVAVFGLIAFCTAYGEGALADWGALHLQEDLAARPGVAAAGYAVFALAMTVGRLSGTALLERVGRTATLVGGGIVAGVGMLFGALAPSLWVALLGFAVTGLGLANLFPVAIERAGALTGPSGVAAASTLGYGGMLLGPPAIGFMAEWGSLPLALVSVAVLAGVAAFVGWGARGAARA
>NZ_CP014485.1|WP_010640322.1|380103_380763_-|alpha-ketoglutarate-dependent-dioxygenase-AlkB
MAALIPRSRTTPAPGAVHVPEWLPEERQRELVEACRGWARGPVPMRRTELPGGGVMSVQSVSLGWHWSPYRYTRRAGDVNGAPVAPLPEWLVELGRRAVADAYQDEAAGRAYRPDVALVNFYGAGATMGMHQDKDERSDAPVVSLSVGDACLFRLGNTEGRGRPWQDLRLESGDLLVFGGPSRFAYHGVPKVYPGTAEPSVGPATGRLNLTLRETGLPG
>NZ_CP014485.1|WP_010640320.1|378813_380052_-|ROK-family-protein
MNGKSAPRTLGGTPPRTRLERGRGALGPALELVRTGRAPTRAVLTSELGVTRATAGVVAAELATLGLIRVDARPTAEGSQGRPSHRLSVDPEGPVVLAAQVHSDGFRAALVGLGGQIVATTPGCETVGADPAEVIGAVVDAGAGLLAETGRRCVGAGLAVPSAVAEPDGTALNPLHLAWPPGAPVREIFRRCVAGAGVPGPAFAANDVNLAALAEHRHGAGRGARDLLCVATGHRGVGGALVLDGRLHSGSSGLALEVGHLTVDPDGRPCHCGGRGCLDVETDPLAFLAAAGHRPGPQGSLLQQARDLIAARPDDPAVREAVTVLVDRLGFGLAGLVNILNPDRVILGGLHRTLLEADPERLRAVVADRSLWGRSGSVPILSCTLDHNSLVGAAELAWQPVLDDPLAALAVV
>NZ_CP014485.1|WP_008416226.1|378188_378725_+|ATP-binding-protein
MISQPTRQCAVELQALPPRIGQVRRIVSAQLRYWHLDPLVDRAALGVTELLTNVHRHAGPDKRCTVRLELLLDRLTVSVRDRDPRLPVVRDATMDATCGRGLALVAAVSECWGVRPWETSGKVVWFTLPAPGPVPAEPGGAALYGATTPGPFPPAALDSALPGLAAGPSAPARSAFAG
>NZ_CP014485.1|WP_003952279.1|377621_377942_+|hypothetical-protein
MGKSEFSATGVGIMRRLRSLTRAGQVRVADGRLALLTSCGRVIDSAPAREVRVERPWFGSDDQAVIAFNDTRYRLRLGGPAAAASAPHVSPVRRLREAVGQARGVG
>NZ_CP014485.1|WP_061403777.1|376160_377297_-|PLP-dependent-cysteine-synthase-family-protein
MTTPQHEQAAACPLPTADVDRSDPGYREWLKEAVRKVQADANRSADTHLLRFPLPEEWGVDLYLKDESTHPTGSLKHRLARSLFLYGLCNGWIRPSRPVIEASSGSTAVSEAYFAQLIGVPFIAVMPRTTSPEKCRLIEFHGGRCHFVDDPRTMYEESARLAAETGGHYMDQFTYAERATDWRGNNNIAESIYQQMRRERHPEPAWVVATAGTGGTSATIARYVHYMQYDTRVCVADPENSCFFDGWRLGDPAVHCDSGSRIEGIGRPRMEPSFLPGAIDRMMKVPDAASVATVRMLEGAIGRRAGGSTGTGLWSALRIVAEMRAEGRTGSVVTLLCDPGDRYLDKYYSDTWLAEQGLDITPYARTLDAFLSTGRRPA
>NZ_CP014485.1|WP_008416220.1|375342_376149_+|DeoR/GlpR-transcriptional-regulator
MGEQQSLLAEQRRALIADEVRRRGGVRVNELTRRLGVSDMTVRRDLDVLARQGVLEKVHGGAVPPADASAHEPGFEAKSGLEPDAKESIAREAAALVSPGTAIALSGGTTTYALAKRLTGVADLTVVTNSVRVADVFHAAQPGAERQAAVVLTGGVRTPSDSLVGPVADQAIRSLHVDVLFIGVHGIAPEAGLSTPNLAEAETNRCLVRSARRVVVVADHTKWGTVGLSSFATLDEVDTLVTDEGLDEEARAEVAERLRLLVVAGPQG
>NZ_CP014485.1|WP_003952271.1|385541_386765_-|geranylgeranyl-reductase-family-protein
MSSENSAGDDRQVWDVVVVGAGPAGASAAYAAAVAGRRVLLLEKAELPRYKTCGGGIIGPSRDNLPPGFDLPLQDRVRAVTFSLDGRFARTRRSRQMLFGLVNRPEFDQRLVEAAQKAGAELRTGATVLRVEQHGPAVPDRRTVAVFVQTSGPGGEREEETLLARAVVGADGSASRIGAHVGVKLDQVDLGLEAEIPVPETVAEDWQGRVLIDWGPMPGSYGWVFPKGDTLTVGVISARGEGAATKRYLTDFIARLGLAGFEPSLSSGHLTRCRTDDSPLSRGRVVVCGDAAGLLEPWTREGISYALRSGRLAGEWALRIAEAHDAVDARRQALNYAFAIKAGLGVEMAVGRRLHQLFARRPGVLHAALTGVRPAWNAFAKVTRGGTTLGELIRNHPVAARMLAGRE
>NZ_CP014485.1|WP_061403781.1|386925_388293_+|dipeptidase
MPSTPIAETVAALMPRAKEELTELVAFRSVADEEQFPRAECEAAADWVADALRGEGFQDVALLDTPDGTRSVYGYLPGPEGARTVLLYAHYDVQPPLDEAAWVTPPFALTERDGRWYGRGAADCKGGFIMHLLALRALKAAGGVPVHVKVIAEGSEEQGTGGLERYAEAHPGLLRSDAIVIGDSGNFRVGVPTVTATLRGMAMARLTVDTLAGNLHSGQFGGAAPDALAALIRVLDSLRDEDGSTTVEGLANEAVWPGLQYPEEEFRKDAKVLDGVRLTGSGTVADRIWARPSVTVIGIDCPPVVGATPSVQASARAQISLRVPPGVDAAEAMKLLAAHLERHVPWGARARVEQIGEGQPFSADTSSPAYQAMAEAMAAAYPGEQMQEAGQGGSIPLTNTLGSLYPEAEILLIGLSEPQAQIHAPNESVAPEELERLAVTEAYFLQNYARTATAG
>NZ_CP014485.1|WP_061403782.1|388340_389321_-|pyridoxal-phosphate-dependent-enzyme
MPRTRLDTGRILAARQLIDPVFLDTPFYRCEALEPRLGCAVNIKLETANPVRSFKGRGTEVVASLLADAGRRAVVCASAGNLGQALAWSGRTRGVDVTVVASRSATTAKLDRIRALGATLELVDGDHESARERAASLARNAGIRLLEDSLDLETCEGAATIGWELVNSRLPFDTVVLALGGGALATGVGHVLKELTPHVEVVCVQALGAPALAYSWRRRRVVTTASTDTIADGVAGRFPIPAVLEDLLLVADDVVLVREESIVAGMRLLLHHAGLVVEPSAALGLAAVIEDRDRFAGRSVATVVCGSNVDMAAHRRWTGGAQAREC
>NZ_CP014485.1|WP_003952268.1|389331_390354_-|NUDIX-hydrolase
MIIWVNGAFGADQTAVAKELTELLPRSVLFDPETVEEQLVRLLPPKRLAEVADLQELPMWRRLVVDTAAALFAETGGDVVVPGSLLRQEYRDEIFGALAARRITVSHVLVDPGETILRARSAETPTGTRTASRPPHDPAAYGAVLSAWLAADAHVLDTRGLSPAQSAQRIADLLHQGGARTCDIVQTPEPTAETVASGVLLFDERERVLLVDPTYKPGWEFPGGIVEPGEAPAAAGVREVAEETGLSLDQADLRLLVMDWEPPMPPGFGGLRLLFDGGRLDSRHATSMLLPGPELRACRFVGLDEAEGLLPPVRFERLRWAVAARGTGGPLYLERGVPLR
>NZ_CP014485.1|WP_015506693.1|390556_391528_-|ROK-family-protein
MTRTELTAALDIGGTKIAAALVDREGRIVLRAQRPTPADQDGERVVAAVHAALGELAAHPDWERAGALGIGSAGPVDASAGTVSPVNIPGWRDFPLVERVREVVGARPVRLIGDGVAVAAAEHWQGAARGYDDALCMVVSTGVGGGLVLGGRLYAGPTGNAGHIGHISVDFDGDLCPCGGRGCVERIASGPHIAARALAEGWRPGPDGDTSAAAVAAAARAGDPVARASFARAGRALAAGIAATATLTEIRIAVIGGGVAAAGDVLFAPLRRALDQYATLAFVRGLTVVPARTGTDAGLIGAAAAVLREDGWGGSAAGRRQAA
>NZ_CP014485.1|WP_061403783.1|391784_392825_+|LacI-family-DNA-binding-transcriptional-regulator
MAQTVRRPAPRYGNRPTMKDVAARAGVGLKTVSRVVNSEPGVTVETERRVREAIDALGFRRNDSARVLRKGRTASVGLILEDLADPFYGPLSRAVEEVARAHGALLINGSSAEDPERERELALALCARRVDGLVVIPAGEDHRYLEPEIAAGVATVFVDRPAGGIEADAVLSDNAGGAREGVAHLLAHGHRRIGFVGDLPHIHTAAERLRGYREAMAEAGAPVDERWVSMGPTGAERVAAEAARLLSGPEPVTALFAGNNRVTVTALRVLADREEPVALVGFDDIELGDLLRPGVTVVAQDAALIGRTAADLLFGRLEGEPARPRQVKLPTRLIVRGSGELRPAGR
>NZ_CP014485.1|WP_003952265.1|392850_394152_-|aldolase
MGQHEQAATSFGSGLTEEIGALLAPVDAELERRYPGDPGTRQPVHTVYVPADAFGPATLRDWGDEALDALDAHAPDAGSFAAVLGLADDLAAPVYDRVRAKLTREPVEDLRIDFEDGYGPRPDAEEDEAAVRAARTVAAAYADGSAAPYMGIRMKCMEAAVRDRGIRTLDLFLTTLLASGPLPSGLVLTLPKVTYAAQVTAMARLLEAFEKTHGLDAGRLGFEIQIETSQSILGPDGTATVARMIDAAEGRATGLHYGTFDYSACLGVAAAHQASDHPAADHAKAVMQVAAAGTGVRVSDGSTNVLPVGPTPKVHDAWRLHYGLTRRALARAYYQGWDMHPAHIPTRYAAVFAFYRESFEQAAARLAAYANRTGGDVMDEPATAKALAAHLLRGLECGALDNGEVARLSGLTRADLEAYARPRRAELGAERGA
>NZ_CP014485.1|WP_049978269.1|394335_395298_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MAEVLVYVDHVDGAVRKPTLELLTLARRIGEPVAVALGAGAADTASALAEHGAVKVLTADAPEFADYLVVPKVDALQAAYEAVSPAAVLLPSSAEAKEIAARLALRIGSGIITDAVDLEAGDEGPVATQSVFAAAFTTKSRVSKGIPVITVKPNSAPVEAAPAAGAVEALSVSFSEKATGTKVVSRTPRESTGRPELTEAAIVVSGGRGVNGAENFAIIEALADSLGAAVGASRAAVDAGWYPHTSQVGQTGKSVSPQLYIANGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDYGVVGDLFEVVPQLTEEVKARKG
>NZ_CP014485.1|WP_003952263.1|395391_396177_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MSLRIVVCVKYVPDATGDRHFADDLTLDRDDVDGLLSELDEYAVEQALQIADEADDAEITVLTVGPDDAKDALRKALSMGADKAVHVEDDDLHGTDVMGTSLVLAKAIEKTGYDLVICGMASTDGVMGVLPAVLAERLGVPQVTLLSEVSVEDGTVKGRRDGDTATEQLEAALPAVVSVTDQSGEARYPSFKGIMAAKKKPVESLDLEDLDIEADEVGLENAWTKVDSATERPARTAGTIVKDEGEGGKQLAAFLAERKFV
>NZ_CP014485.1|WP_010640359.1|396378_396963_-|flavin-reductase-family-protein
MPPAENRTAPRLPSPSSPDPGSPHGGTDGSADARAPLDGSPELLRAAFRRHPAGVAVITARGSRLAGFTATSLTSVSAEPPLVSFGVGTASGSWPVIAEAEHVGVHLLGEHQRELAGLFARSGADRFAPPTRWREGPEGVPLLESVPVWLVCRVVARVPAGDHRVVVAEVVAGDPAGPGRPLVHHDGCYNALRD

Crispr_ID: NZ_CP014485_2

• CRISPR_ID: NZ_CP014485_2
• CRISPR_location: 1092797-1092913
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DEDDh

Consensus repeat of NZ_CP014485_2

Consensus_repeat	Method
GATGGCCTCAAACGCCGGCCGGGCTG	CRISPRCasFinder

spacers of NZ_CP014485_2

>2.1|1092823|65|NZ_CP014485|CRISPRCasFinder
GAAGATGGCCTCAAACGCCGGCCGGGCTGGATTCGGCTGAGATCCGGCCTCAACCACCGGTCACT

CRISPR arrays and Neighbor proteins around NZ_CP014485_2

CRISPR arrays

The CRISPR arrays of NZ_CP014485_2

>merge|NZ_CP014485|2|1092797-1092913|CRISPRCasFinder
GGTGGCCTCAAGCGCCGGCCAGGCTCGAAGATGGCCTCAAACGCCGGCCGGGCTGGATTCGGCTGAGATCCGGCCTCAACCACCGGTCACTGATGGCCTCAAACGCCGGCCAGGCTG

>NZ_CP014485|2|2|1092797-1092913|CRISPRCasFinder
GGTGGCCTCAAGCGCCGGCCAGGCTC	GAAGATGGCCTCAAACGCCGGCCGGGCTGGATTCGGCTGAGATCCGGCCTCAACCACCGGTCACT
GATGGCCTCAAACGCCGGCCAGGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003951623.1|1091986_1092769_+|sirohydrochlorin-chelatase	unknown	unknown	gnl|CDD|225049
NZ_CP014485.1|WP_003951613.1|1101821_1103063_-|hypothetical-protein	unknown	unknown	gnl|CDD|376148
NZ_CP014485.1|WP_059213930.1|1096430_1097054_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061403982.1|1085809_1086475_+|adenylyl-sulfate-kinase	unknown	unknown	gnl|CDD|238985
NZ_CP014485.1|WP_018895718.1|1085080_1085806_+|phosphoadenylyl-sulfate-reductase	unknown	unknown	gnl|CDD|234997
NZ_CP014485.1|WP_031176958.1|1098896_1099961_+|membrane-protein	unknown	unknown	gnl|CDD|274414
NZ_CP014485.1|WP_008403888.1|1088769_1088934_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061403983.1|1087415_1088768_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|180120
NZ_CP014485.1|WP_008403897.1|1084901_1085084_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003951629.1|1086471_1087413_+|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl|CDD|235375
NZ_CP014485.1|WP_008410980.1|1100983_1101697_-|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|181176
NZ_CP014485.1|WP_003951621.1|1093986_1094475_+|glutathione-peroxidase	unknown	unknown	gnl|CDD|238207
NZ_CP014485.1|WP_003951615.1|1100097_1100958_+|aminoglycoside-phosphotransferase-family-protein	unknown	unknown	gnl|CDD|366736
NZ_CP014485.1|WP_003951625.1|1090255_1091080_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224041
NZ_CP014485.1|WP_003951624.1|1091066_1091984_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
NZ_CP014485.1|WP_015506885.1|1093308_1093911_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP014485.1|WP_003951620.1|1094593_1095805_-|S8-family-peptidase	unknown	unknown	gnl|CDD|173790
NZ_CP014485.1|WP_018895720.1|1089054_1090173_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270271
NZ_CP014485.1|WP_008410987.1|1098354_1098783_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP014485.1|WP_003951618.1|1097063_1098188_-|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_008410980.1|1100983_1101697_-|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	1.5e-36	120.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003951623.1|1091986_1092769_+|sirohydrochlorin-chelatase	gnl|CDD|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	1.73646e-28
NZ_CP014485.1|WP_003951613.1|1101821_1103063_-|hypothetical-protein	gnl|CDD|376148	pfam18725, HEPN_SAV2148, SAV2148-like HEPN. SAV2148-like HEPN nuclease domain.	2.75976e-127
NZ_CP014485.1|WP_061403982.1|1085809_1086475_+|adenylyl-sulfate-kinase	gnl|CDD|238985	cd02027, APSK, Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form important for the assimilation of inorganic sulfate.	7.51222e-78
NZ_CP014485.1|WP_003951621.1|1093986_1094475_+|glutathione-peroxidase	gnl|CDD|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	6.87729e-86
NZ_CP014485.1|WP_003951615.1|1100097_1100958_+|aminoglycoside-phosphotransferase-family-protein	gnl|CDD|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	1.16726e-12
NZ_CP014485.1|WP_018895718.1|1085080_1085806_+|phosphoadenylyl-sulfate-reductase	gnl|CDD|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.40841e-113
NZ_CP014485.1|WP_061403983.1|1087415_1088768_+|50S-ribosome-binding-GTPase	gnl|CDD|180120	PRK05506, PRK05506, bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Provisional.	0
NZ_CP014485.1|WP_008410980.1|1100983_1101697_-|DNA-polymerase-III-subunit-epsilon	gnl|CDD|181176	PRK07942, PRK07942, DNA polymerase III subunit epsilon; Provisional.	3.31956e-108
NZ_CP014485.1|WP_003951629.1|1086471_1087413_+|sulfate-adenylyltransferase-subunit-CysD	gnl|CDD|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP014485.1|WP_003951618.1|1097063_1098188_-|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	3.82123e-21
NZ_CP014485.1|WP_003951625.1|1090255_1091080_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	3.94432e-109
NZ_CP014485.1|WP_003951624.1|1091066_1091984_+|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	4.47304e-54
NZ_CP014485.1|WP_015506885.1|1093308_1093911_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.41458e-19
NZ_CP014485.1|WP_003951620.1|1094593_1095805_-|S8-family-peptidase	gnl|CDD|173790	cd04077, Peptidases_S8_PCSK9_ProteinaseK_like, Peptidase S8 family domain in ProteinaseK-like proteins. The peptidase S8 or Subtilase clan of proteases have a Asp/His/Ser catalytic triad that is not homologous to trypsin. This CD contains several members of this clan including: PCSK9 (Proprotein convertase subtilisin/kexin type 9), Proteinase_K, Proteinase_T, and other subtilisin-like serine proteases. PCSK9 posttranslationally regulates hepatic low-density lipoprotein receptors (LDLRs) by binding to LDLRs on the cell surface, leading to their degradation. The binding site of PCSK9 has been localized to the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR. Characterized Proteinases K are secreted endopeptidases with a high degree of sequence conservation. Proteinases K are not substrate-specific and function in a wide variety of species in different pathways. It can hydrolyze keratin and other proteins with subtilisin-like specificity. The number of calcium-binding motifs found in these differ. Proteinase T is a novel proteinase from the fungus Tritirachium album Limber. The amino acid sequence of proteinase T as deduced from the nucleotide sequence is about 56% identical to that of proteinase K.	6.56464e-124
NZ_CP014485.1|WP_018895720.1|1089054_1090173_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.62904e-54
NZ_CP014485.1|WP_008410987.1|1098354_1098783_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.09713e-12
NZ_CP014485.1|WP_031176958.1|1098896_1099961_+|membrane-protein	gnl|CDD|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	4.38194e-08

Protein sequences

>NZ_CP014485.1|WP_003951623.1|1091986_1092769_+|sirohydrochlorin-chelatase
MRHLILPSSASAAPVLMVVAHGSRDPRHAATVHALVERVRGLAPGLRVEPAFLDFDAETVPDLLERLHAEGVRDVVALPLLLTRAFHAKADLPAVLRESAARLPLLRVRQAGVLGPSPLLVAALERRLGEAGVELGQRGSTGVVLASAGSSDAEAIAVIAEIAREWRRTGWCAVRPAFASACGPGRPRTEDAVAAMRAGGARRVVVAPYVLAPGRLPDRIAAGAAGADVLAPVLGAAPEVARLVLRRYREAGAGGRLVAA
>NZ_CP014485.1|WP_003951624.1|1091066_1091984_+|ABC-transporter-permease
MASTETRDAAEEAAREPKKPSEDLAGLEAGLDALDAVPTRRTSLRDTFVRKVLPPLVAVALVLVVWQVLVWAQVTEEYKLPSPGAVWGEVTDAWYQGTLLGYIWTSVSRGLLGFLFALAIGTPLGLLVARVKFVRAAIGPILSGLQSLPSVAWVPPAVIWLGLNDQMMFAVILLGAVPSIANGLVSGVDQVPPLYLRAGRTLGATGLRGTWHIVMPAALPGYLAGLKQGWAFSWRSLMAAEIIASSPELGIGLGQLLENGRVASSMSMVFLAILLILVVGVAIDLLIFSPLERWVLRNRGLLARS
>NZ_CP014485.1|WP_003951625.1|1090255_1091080_+|ABC-transporter-ATP-binding-protein
MTTTVTEAGPADGTSAGAAPSPAARIAHVSKSFPGPAGDQLVLDDITLDVAPGEFVTLLGASGCGKSTLLNLVAGLDAPSAGTIETPGRPALMFQEHALFPWLTAGKNIELALKLRGVPKPERRPRAEELLERVRLAGAHGKRVHELSGGMRQRVALARALAQDSRLLLMDEPFAALDAITRDVLHDELTRVWHAANDDPDGRKLSVLFVTHNVREAVRLAERVVLLSSRPGRVARQWTVDIPQPRRIEDAAVAELSVEITEELRGEIRRHGQH
>NZ_CP014485.1|WP_018895720.1|1089054_1090173_+|ABC-transporter-substrate-binding-protein
MPASRPPFRTRTRALAAVAALPLLVGALASCGYGSDAADDKKPEKAAGGSKLSTDQVKIGYFPNLTHATALVGVEKGLIEKELGGAELVPSTFNAGPSEIEALNSGSIDIGFIGPSPSVNGYVKSKGDSLRIISGSASGGVKLVVNPDKIKTVKDLKGKKIATPQLGNTQDVAFLHWISEQGWKVDAQSGKGDVSVVRTDNKITPDAYKSGSLDGAWVPEPTASKLVADGAKVLLDEADLWPDKKFVITNIIVSQKFLKEHPDAVEAVLRGSVKTNKWINDNPEEAKASANDALKTLTGKPLPAEVLDPAWKSIQITDDPLAATLDSQAEHAVNAGLLEQPDLNGIYDLRPLNKVLEAEGAPAVDDAGLGVK
>NZ_CP014485.1|WP_008403888.1|1088769_1088934_+|hypothetical-protein
MTTDGSTAPGADRARHADPGHFFADVYGTFAKEGGRVGSGALGSGQGGVARCAR
>NZ_CP014485.1|WP_061403983.1|1087415_1088768_+|50S-ribosome-binding-GTPase
MTTTATTTAEQLSATTLLRFATAGSVDDGKSTLVGRLLHDSKSVLTDQLEAVEAASLSRGHEGPDLALLTDGLRAEREQGITIDVAYRYFATPRRRFILADTPGHVQYTRNMVTGASTAELAVVLVDARNGVVEQTRRHAAVAALLRVPHVVLAVNKMDLVDYAEPVYAAIAEEFTAYATSLGVPEVTTIPISALAGDNVVEPSARMDWYAGPTVLEHLETVPVSHDLTACAPRFPVQYVIRPQSAEHRDYRGYAGQIASGALRVGEEVVVLPSGRTTTVAAIDVLGEPTDIAWAPQSVTVRLTDDVDVSRGDLIAPVAEAPELTREVTATVCHVADTPLTEGQRVLLKHTTRTVKAIVEAIPSRLTLDDLSQHPEPGRLEANDIGRVRLRTAEPLALDAYALSRRTGSFLLIDPADGTTLTAGMAGDAFADSAAAAEPAPEADDEGWDF
>NZ_CP014485.1|WP_003951629.1|1086471_1087413_+|sulfate-adenylyltransferase-subunit-CysD
MTTVASSARAAGPETPYALSHLDALESEAVHIFREVAGEFERPVILFSGGKDSIVMLHLALKAFAPAPVPFSLLHVDTGHNFPEVLEYRDRTVAEHGLRLHVASVQEYIDRGDLRERPDGTRNPLQTVPLTDAIREQRFDAVFGGGRRDEEKARAKERVFSLRDAFSQWDPRRQRPELWQLYNGRHAPGEHVRVFPLSNWTELDVWQYIARESIALPEIYFAHERPVFRRSGMWLTAGEWGGPKDDEPVETRLVRYRTVGDMSCTGAVDSDATTLDAVITEIAASRLTERGATRADDKLSEAAMEDRKREGYF
>NZ_CP014485.1|WP_061403982.1|1085809_1086475_+|adenylyl-sulfate-kinase
MTTTDAPPTGAATSQIHPPQHHPQRQEKNVTGATVWLTGLPSAGKTTLAREVAALLAADGHRTEVLDGDEIRTFLSAGLGFERADRDTNVQRIGFVAELLASHGVTVLVPVIAPYADSRAAVRERHAKNGTPYLEVHVATPVEVCAERDVKGLYARQAAGEISGLTGVDDPYEVPEAPDLRIETHGSTVAESAETLRTLLAGLGLLTPAPPAGSDDERRSA
>NZ_CP014485.1|WP_018895718.1|1085080_1085806_+|phosphoadenylyl-sulfate-reductase
MSGIRTEPAAADAGEDELRTLAERAGAELEEAPALEIVRWAADTFGERFCVTSSMEDAVVAHLASRVRPGVDVVFLDTGYHFPETIGTRDAVEAVLDVNVLTLTPRQSVAEQDAEYGPKLHDRDPDLCCALRKVKPLEEGLAGYAAWATGLRRDESPTRANTPVVGWDARRRKVKVSPIARWTQDDVDAYVARYGVLTNPLLSDGYASVGCAPCTRRVAAGEDARAGRWAGTGKTECGLHG
>NZ_CP014485.1|WP_008403897.1|1084901_1085084_+|hypothetical-protein
MSERAAPFHCPYCGDEDLRPGEQGHGAWECAACNRAFQLKFLGLLTRGLARTPDGEGEAT
>NZ_CP014485.1|WP_015506885.1|1093308_1093911_+|class-I-SAM-dependent-methyltransferase
MDAQYWDEKYRSTDQLFSGAPNAVLVAEVAELPPGHALDLGCGEGADAHWLARHGWRVTAVDIAPTALRRAAEAAPELADQVTWTAADITRTPPAPRTYDLVSAHYFPLPRTADHTALHGLLEAVAPGGTLLFTGHDLADLADHLEQEYTPHDFYQPAEVAALLGEEWTVLVDETRPRTTPPPPGTGHTHDTVLRARRRP
>NZ_CP014485.1|WP_003951621.1|1093986_1094475_+|glutathione-peroxidase
MSVLDVEIDALTGGSADLSQYRGSAVLVVNVASRCGLTPQYAGLEKLHQRYAARGFTVLGVPCNQFMGQEPGTAEEIATFCSATYGTSFPMTQKTDVNGAERHPLYTGLVGTADAEGHTGDIRWNFEKFLIAPDGTVAARFAPQTEPEAEEIAAAVEAVLPR
>NZ_CP014485.1|WP_003951620.1|1094593_1095805_-|S8-family-peptidase
MATHQRARRTKLTAAIATTAMAVGVTVFASPFAGAAPAPAEGKVYGTAAKGAVSGSYIVMLDEKASKAEKKGLAKEYGGTFKRNYGSAVNGFSTAGMSLEDAKRLAADPAVEKVVQNKKFTIDATQTNPPSWGLDRIDQTETAGDGEYTYPDAAGEGVTAYVIDTGVRVTHEDFEGRATSGYDAVDGDDDADDGNGHGTHVAGTIAGAAHGVAKKANIVAVRVLDDNGSGTTEQVVAGIDWVTENHSGPSVANMSLGGGADEALDTAVRNSIAAGVTYGVAAGNESSDASSSSPARVEEAITVASSDEDDAQSSFSNYGDIVDIYAPGSEITSAWNTGDDATNTISGTSMATPHVVGAAAVYLGGNPEATPEEVATALTDGATPDAITNPSAGTPNLLLKVVE
>NZ_CP014485.1|WP_059213930.1|1096430_1097054_+|hypothetical-protein
MTLSHAPSPDALDEEAARLHESAVWQELVASWPTTAAPEETCLRPAAPQEEWRALLSVPVADLVAEAARALPAPDPAVASPLPGRVGAVLPDRLYGWRRAGRVEVLPSVHMAYARRVLVEWGWQNRPYRMRNLRGARCLCGALLTTHRLGHGSLDTANRSAAWLMTELRERGWRDLIGPWNRAPGRTAAEALELLDAASARARRAGE
>NZ_CP014485.1|WP_003951618.1|1097063_1098188_-|mechanosensitive-ion-channel
MENVLRPLIVVGGALALTLLLGWLADLLLRRANARHPETPLWGLLRRCRPPLQVVLLTAILRGAYRQTKLDIIQDHEAGIGQVLSLVLIASTAWLVLRAAAAAVESTYARYASMSADRARVRRVRTQVTLIMRIVTAVVCVVAGAAMLLTFPELRAVGTSMLASAGIIGIVAGVAAQSTLGNLFAGFQIAFGDMVRLGDTVVVDGEWGVIDEVTLTVVAVRTWDERRITMPVSYFTSQPFENWSRGGVQMTGSVFLQLDHRAPLSLMRKKTEEILEHCEAWDRRSWSLAVTDSTATTMEVRVVVTARDADDIWTARCTVREQLLVWLAEEHPYALPRVTTGAADPLPPRPAGGLLGKDGTAADEHRELPDTGRG
>NZ_CP014485.1|WP_008410987.1|1098354_1098783_-|MarR-family-transcriptional-regulator
MNHRDEALETIQREMTAFARRARAAAAHLHPELSLVSYTLLSHLETRQGMRATDLAAHYLLDKSTISRQIGALERSGLIERRTAEDDHRVHVLHLTAGGKQALDEATEVRRAAYRERLGDWDEADLDRFAGYLLRYNGADGN
>NZ_CP014485.1|WP_031176958.1|1098896_1099961_+|membrane-protein
MSSVREPAAHAAASSGALRHVLLHLVTPLLMCLGMGLAYLSAFVSPEPHQVPVAVVGSGPQTQVLAQTLKDEDGEALDVRTVADRGEAQELLRGQELSGAFVPDADRPELLIASAASDMSALAVQKVFTPLAAGQGAPLTVTDVATPVEDDPTGQGLFFLLVAVSIGGYASVAVVGGAGGALPMRLRALLVAGVSLVVSLIGTALAGPVFHLAHHSLWAVWGLSWLYAAGILAIGTGLHTFLKRWTTLAMMVLFVMLNFTSSGGLFLPHLQNGFFGALHAFWNGAGFVEGLRSVLYFDSRGLGGHLWTLVAWLAVGAVALLAAAAYERRGRRAAALPAPGPEEAEEEMEESVAV
>NZ_CP014485.1|WP_003951615.1|1100097_1100958_+|aminoglycoside-phosphotransferase-family-protein
MDEPQARSVLAAAGLSTPAEEATLLAFGENAVFAFGDVVAKVGRAPELLERARRELRIAVWLQEQGVPAVRAVQPEPLLVDGHPVTLWRRLSEPVRPAAPADLAALLRQVHALEPPPFGLPRRELLGGVERWLRLAGDAIDPADADYLRERRDGFAKAAAALVPHLPPGPIHGDALPRNVHIGPDGPVLTDLETFSSDFREHDLVVLALSRDRYGLPAEEYRRFTSVYGWDVREWDGCAVLRGARETASCAWVSQHAPGNPKALAEFRRRVASLRDGDTEVRWHPF
>NZ_CP014485.1|WP_008410980.1|1100983_1101697_-|DNA-polymerase-III-subunit-epsilon
MGWHRELLIGFDLETTGTDPREARIVTAAVIEVADGERRGHRTWLADPGIPIPAGATAVHGITDARAAAEGSPPDRVADAVAEALTGYWRAGVPVVAYNAPFDLTLLAAELRRHRLPSLAERLGGAPVGPVIDPLTVDRAVDRYRKGSRRLSAVCAEYGVTLEEAHDASADALAAARLARAIALRHPKVAALGAAALHERQIGWAAERAADFQAYLRRKGERGAVVDGGWPLHAEAA
>NZ_CP014485.1|WP_003951613.1|1101821_1103063_-|hypothetical-protein
MSSGGLELPPGDPGHEGGSGEVPSGAVSLARPVETGAQIGPELDWGADAWSEVRTRAQRAGRAYIWLNLVEQRLRAVVAAVLRPVYEPVHGEDWVVAAAGPAGQEWVQRAVAVREVSRRKGYLLDPADDNVLSFLTLPQLRELMVQHWPCFEPYFDDRRAVELALDELEVTRNVVSRNRALSQAVLSQAERASAVLLEMLGAGSDVPSARRLRVDAVEDLVGDRYADVVGVHPDRVRLLRQFPAEDLFGGARRLDAIGIGLNLLVQNFSGRRLVRLAEEGSRVRLLFLNPASSAVKRRERELGLKRGELSRSVEMNILHMRRVRARLRDPGAFEIQVYDETPRFTAYLVDGDGSDGVAVVQSYLRRTRGMEAPVLVLRGGGRVVRGEGPGENGLFETYREEFELAWADSRPVS

Crispr_ID: NZ_CP014485_3

• CRISPR_ID: NZ_CP014485_3
• CRISPR_location: 1471618-1471720
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_3

Consensus_repeat	Method
AAGCCCGGCCGGCGATTGAGGCCACCC	CRISPRCasFinder

spacers of NZ_CP014485_3

>3.1|1471645|49|NZ_CP014485|CRISPRCasFinder
CACCAGCACCGAAGACGTGCGGCAGCAAACGCAGCGGCTCGCCCGAATC

CRISPR arrays and Neighbor proteins around NZ_CP014485_3

CRISPR arrays

The CRISPR arrays of NZ_CP014485_3

>merge|NZ_CP014485|3|1471618-1471720|CRISPRCasFinder
AAGCCCGGCCGGCGATTGAGGCCACCCCACCAGCACCGAAGACGTGCGGCAGCAAACGCAGCGGCTCGCCCGAATCAAGCCCGGCCGGCGTTTGAGGCCACCC

>NZ_CP014485|3|3|1471618-1471720|CRISPRCasFinder
AAGCCCGGCCGGCGATTGAGGCCACCC	CACCAGCACCGAAGACGTGCGGCAGCAAACGCAGCGGCTCGCCCGAATC
AAGCCCGGCCGGCGTTTGAGGCCACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_030698178.1|1468196_1468841_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
NZ_CP014485.1|WP_008406633.1|1470935_1471394_+|DUF3093-domain-containing-protein	unknown	unknown	gnl|CDD|378627
NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein	unknown	unknown	gnl|CDD|378619
NZ_CP014485.1|WP_079075963.1|1471740_1472676_-|hypothetical-protein	unknown	unknown	gnl|CDD|378945
NZ_CP014485.1|WP_008406623.1|1463995_1466554_-|sensor-histidine-kinase-KdpD	unknown	unknown	gnl|CDD|225115
NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein	unknown	unknown	gnl|CDD|281959
NZ_CP014485.1|WP_003951344.1|1467388_1468180_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235546
NZ_CP014485.1|WP_003951348.1|1462814_1463222_-|OB-fold-nucleic-acid-binding-domain-containing-protein	unknown	unknown	gnl|CDD|239934
NZ_CP014485.1|WP_003951340.1|1470293_1470878_-|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_CP014485.1|WP_003951341.1|1469781_1470297_-|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NZ_CP014485.1|WP_061404094.1|1466576_1467320_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP014485.1|WP_061404097.1|1480557_1481742_-|hypothetical-protein	unknown	unknown	gnl|CDD|223039
NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP014485.1|WP_003951337.1|1472688_1472985_-|DUF4193-domain-containing-protein	unknown	unknown	gnl|CDD|379391
NZ_CP014485.1|WP_003951336.1|1473379_1474651_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP014485.1|WP_003951347.1|1463270_1463966_-|response-regulator	unknown	unknown	gnl|CDD|182522
NZ_CP014485.1|WP_037845666.1|1469015_1469780_-|DUF3710-domain-containing-protein	unknown	unknown	gnl|CDD|378867
NZ_CP014485.1|WP_008406645.1|1476751_1477867_-|ferrochelatase	unknown	unknown	gnl|CDD|234585
NZ_CP014485.1|WP_010641647.1|1475908_1476718_-|inositol-monophosphatase	unknown	unknown	gnl|CDD|238817
NZ_CP014485.1|WP_033240980.1|1474656_1475310_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_030698178.1|1468196_1468841_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	4.55956e-11
NZ_CP014485.1|WP_008406633.1|1470935_1471394_+|DUF3093-domain-containing-protein	gnl|CDD|378627	pfam11292, DUF3093, Protein of unknown function (DUF3093). This family of proteins with unknown function appears to be restricted to Actinobacteria. Some members are annotated as alanine rich membrane proteins however this cannot be confirmed.	1.57638e-49
NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein	gnl|CDD|378619	pfam11268, DUF3071, Protein of unknown function (DUF3071). Some members in this family of proteins are annotated as DNA-binding proteins however this cannot be confirmed. Currently no function is known.	3.71985e-61
NZ_CP014485.1|WP_079075963.1|1471740_1472676_-|hypothetical-protein	gnl|CDD|378945	pfam12787, EcsC, EcsC protein family. Proteins in this family are related to EcsC from B. subtilis. This protein is found in an operon with EcsA and EcsB which are components of an ABC transport system. The function of this protein is unknown.	0.000117094
NZ_CP014485.1|WP_008406623.1|1463995_1466554_-|sensor-histidine-kinase-KdpD	gnl|CDD|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein	gnl|CDD|281959	pfam04030, ALO, D-arabinono-1,4-lactone oxidase. This domain is specific to D-arabinono-1,4-lactone oxidase EC:1.1.3.-, which is involved in the final step of the D-erythroascorbic acid biosynthesis pathway.	7.96812e-116
NZ_CP014485.1|WP_003951344.1|1467388_1468180_-|SDR-family-oxidoreductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.99008e-77
NZ_CP014485.1|WP_003951348.1|1462814_1463222_-|OB-fold-nucleic-acid-binding-domain-containing-protein	gnl|CDD|239934	cd04488, RecG_wedge_OBF, RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a four-stranded (Holliday) junction in vivo and in vitro. This interconversion provides a route to repair stalled forks. The RecG monomer contains three domains. The N-terminal domain is named for its wedge structure, and may provide the specificity of RecG for binding branched-DNA structures. During the reversal of fork to Holliday junction, the wedge domain is fixed at the junction of the fork where the leading and lagging strand duplex arms meet, and is thought to promote the unwinding of the nascent leading and lagging strands. In order to form the Holliday junction, these nascent strands would be annealed, and the parental strands reannealed. The wedge domain may also be a processivity factor of RecG on these branched chain substrates.	1.683e-15
NZ_CP014485.1|WP_003951340.1|1470293_1470878_-|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.00993e-11
NZ_CP014485.1|WP_003951341.1|1469781_1470297_-|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	4.54717e-73
NZ_CP014485.1|WP_061404094.1|1466576_1467320_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.31826e-102
NZ_CP014485.1|WP_061404097.1|1480557_1481742_-|hypothetical-protein	gnl|CDD|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	9.08461e-05
NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.43622e-19
NZ_CP014485.1|WP_003951337.1|1472688_1472985_-|DUF4193-domain-containing-protein	gnl|CDD|379391	pfam13834, DUF4193, Domain of unknown function (DUF4193). This domain of unknown function contains four conserved cysteines and a conserved histidine, including a CXXXXH motif.	1.90861e-60
NZ_CP014485.1|WP_003951336.1|1473379_1474651_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.86374e-51
NZ_CP014485.1|WP_003951347.1|1463270_1463966_-|response-regulator	gnl|CDD|182522	PRK10529, PRK10529, DNA-binding transcriptional activator KdpE; Provisional.	2.18409e-84
NZ_CP014485.1|WP_037845666.1|1469015_1469780_-|DUF3710-domain-containing-protein	gnl|CDD|378867	pfam12502, DUF3710, Protein of unknown function (DUF3710). This family of proteins is found in bacteria. Proteins in this family are typically between 237 and 284 amino acids in length. There are two conserved sequence motifs: DLG and DGPRW.	2.75718e-75
NZ_CP014485.1|WP_008406645.1|1476751_1477867_-|ferrochelatase	gnl|CDD|234585	PRK00035, hemH, ferrochelatase; Reviewed.	1.8658e-128
NZ_CP014485.1|WP_010641647.1|1475908_1476718_-|inositol-monophosphatase	gnl|CDD|238817	cd01639, IMPase, IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria.	3.32006e-97
NZ_CP014485.1|WP_033240980.1|1474656_1475310_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.34314e-69

Protein sequences

>NZ_CP014485.1|WP_008406633.1|1470935_1471394_+|DUF3093-domain-containing-protein
MHPNTPQYAERLTAPRAWWALVAIAGLTSGLIVMPLGVLAMLIGLVVGAAAGAAGLSTYGSAQIRVVGDALVAGDARIPLSALGAAEPLDAEETVAWRSHKADPRAFMLLRSYIPTAVRVEVTDPADPTPYLYLSTRDPERLAAALSPVREG
>NZ_CP014485.1|WP_003951340.1|1470293_1470878_-|PaaI-family-thioesterase
MSGRTPALTPPDSALAPVRHPDAPAPGEPIGTHYEHCFGCGGEQPHGLHLAAKAGEGVSVTAEFLVRPEHQGAPGLAHGGLLATALDDTLGALNWLLRVISVTGRLETDYLRPVPVGTVLHLSAEVTAVDGRKIYATAEGRLNAPDGPVAVRADALFVEVKVEHFTDNGRPEEIQAAMDDPDQIRRVRAFEVNP
>NZ_CP014485.1|WP_003951341.1|1469781_1470297_-|dUTP-diphosphatase
MTRPPLDLRVRRLHPEVPLPAYGNPGDAGADLCTTEPAVLAPGERAVLPTGIAIALPEGYAAFVHPRSGLAARCGLALVNAPGTIDAGYRGEIKVIVVNLDPREKVRFERFDRIAQLVVQQVETVRFHEVSELPGSVRAEGGFGSTGGHSAVGGGEGGNHYASVVADREGQ
>NZ_CP014485.1|WP_037845666.1|1469015_1469780_-|DUF3710-domain-containing-protein
MFGRRKKTDSAEDTAGVTGETGQAEESADAEESATRRTALPPAPRPDGPWDASEVREPGEGRVDLGGLFVPGVEGMELRVEVAGDAIVAATVVLRDSAIQLQGFAAPKKEGIWGEVREEIGSGITQQGGIIEEVEGPLGWELRAQVPVQLPDGKSGYQVVRFVGVDGPRWFLRGVISGQGAVQPQAAGLLEQIFQDTVVVRGEGPMAPRDPIVLKLPDDAQMVPEGVQQENQQTSRFSGGMGQLARGPEITEIR
>NZ_CP014485.1|WP_030698178.1|1468196_1468841_-|TetR/AcrR-family-transcriptional-regulator
MKATETSGEDRRRLKARQTRTALAAAALDLILERGLNAVTVEAVAHRADVTRRTFSRHFGGKEDAALDFTREDGAAINAALRARPACEPPLVAYRRAVRDWLADTRTPGWHQLPRVRSLLALVDDEPTLFAAFERIRADAQEESVRIIAERLGTDPAEDPGPGVVVGAAAGVLTAALRQWWRGGPESAERLPDLVEQSFDVLLGEVALAAPHAP
>NZ_CP014485.1|WP_003951344.1|1467388_1468180_-|SDR-family-oxidoreductase
MSTSAPLPSATPVSPDEFAGRTALVTGAASGIGLATARRLGQGGARVVIADYNAEGAASAAAALRDESVEASAVTVDVTDPASVEAAVRFAQDTYGALHLAVNNAGIGGESAPTGDYDIDVWNRVVRTNLDGVFYSMRYEIPALLAAGGGAIVNTASILGSVGFAGSPAYVAAKHGVVGLTKTAATEYAAQGVRINAVGPGFIDTPLLQGMDKQAYDGLVQLHPAGRLGRSEEVAEVIAFLLSDRASFVHGSYHLVDGAYTAR
>NZ_CP014485.1|WP_061404094.1|1466576_1467320_-|ABC-transporter-ATP-binding-protein
MAGRTAGGGTLTEDAGAAAGTGEEPMVKVCGLRRSYGTGEGAVHALRGVSFDIPRGELVALKGRSGSGKTTLLNLVGGLDEPDGGSVVVDGRELSGLGEKGLLELRRDRIGFIFQSFGLIPVLSAAENVGVPLRLRRAEAAEREERVALLLSLVGLADHARQRPGELSGGQQQRVAVARALANRPALLIADEPTGQLDAETGLAVMELLRAVVRSERVTVLVATHDTTLLGLADRVLELSDGELTEQ
>NZ_CP014485.1|WP_008406623.1|1463995_1466554_-|sensor-histidine-kinase-KdpD
MGRGTLRIYLGAAPGVGKTYAMLSEAHRRVGRGTDCVIGFVAHHDRPRTLALLDGLELIEPLGGPDGDGGTPQTPEMDVEAVLARRPAVALVDELAHTNAPGARNAKRWQDVEELLAAGISVISTVNIQHLESLGDVVEAITGVRQQETVPDEVVRRADQIELVDMSPQALRRRLAHGNVYQSDKVDAALSNYFRPGNLTALRELALLWTADRADEYLQKYRGEHNIRSTWQARERIVVGLTGGPEGRTLIRRAARMAAKGSGSEILAVYIARRDGGLTTASPKELALQRTLVEDLGGTFHHVIGDDIPSALLEFARGVNATQIVLGSSRRKSWQYVFGPGVGATVARESTPDLDVHIVTHEEVGQGRGLPVARGARLGRSRILWGWFIAVCGPALLAIVLSSLDHGPGLANDVLLFLSLTVGAALVGGLLPALASAALCSALLNFYFTPPTRTLTISDPENIVAIVISFAVAVSVASVVDLAARRTHQAARLRAESEILSFLAGSVLRGATTLDALLERVRETFAMESVALLEREDDRTPWTCAGSVGPRPLERPEDADVDMPVGDHMALALCGRVLPAEDRRVLAAFAAQAAVVLDRQRLQDEADQARRLAEGNRIRTALLAAVSHDLRTPLAAIKASVTSLRSDDVAWSEQDEAELLESIEHGADRLDHLVGNLLDMSRLQTGTVTPLIREIDLDEVVPMALGGVPEGSAQLDIPETLPMVAVDPGLLERSVANVVENAVKYAPEGAPVLVAASALGDRVELRVMDRGPGVPDDAKDRIFAPFQRYGDAPRGAGVGLGLAVARGFAEAMGGTLNAEDTPGGGLTMVLTLRAVTGPRAGARTVLPAQVTS
>NZ_CP014485.1|WP_003951347.1|1463270_1463966_-|response-regulator
MTRVLVVDDEPQIVRALELNLRARQYEVDSAGDGTTALRLAAERHPDVIVLDLGLPDMDGVDVLRGLRSWSRVPVLVLSARQSSDEKVQALDAGADDYVTKPFGMDELLARLRAAVRRTEPAAPDEEAEVVDAADFTVDLAAKRVHRQGRDVRLTPTEWHLLEVLVRNTGRLVSQKQLLQEVWGPSYGTESNYLRVYMAQLRRKLETDPAHPRHFITEPGMGYRFERRPQG
>NZ_CP014485.1|WP_003951348.1|1462814_1463222_-|OB-fold-nucleic-acid-binding-domain-containing-protein
MSAAPRPEKPAGRFRRMLDRLSDISAPQERLESDELREEAATSGCARIDTCGDREMVTVTGTLRTVTLRPRAGVPALEAELFDGSGSLDVVWLGRRSITGIEPGRKLIASGRVAMSHGRRTLFNPKYELRPLGRE
>NZ_CP014485.1|WP_079075963.1|1471740_1472676_-|hypothetical-protein
MTGTTPPRKFPFLKRRGDGAPSPAESDGERGLGASLEAADATDGAPGPHSGGSGTGEGPAATEPATPAPGRVAAVRDGLLRQGRNAKAGLGVLADRVIEIAPRIPVRDLHTLRAQFPGLGPEQLADKLISGAAHGTSTVGASVGAAAMLPVPPAMPAELAAEITAVAAIELKLIAELHEVYGQRPEGGATRRATAYLTSWTNERGIDVVRPLTITAALSGPLKRDLRQQITKRMIRNLPNLVPFLVGAAVGAVMNRRDTRKLAERVRQDLRVAQVPWDQLTSLPPLDRPELPPATLPHALPPAPRDDNRPT
>NZ_CP014485.1|WP_003951337.1|1472688_1472985_-|DUF4193-domain-containing-protein
MATDYDTPRKTDDDLNEDSIEELKARRNDKSTSTVDVDEFEAAEGLELPGADLSNEELAVRVLPKQQDEFTCMSCFLVHHRSQLAREKNGQPICRDCD
>NZ_CP014485.1|WP_003951336.1|1473379_1474651_-|HAMP-domain-containing-histidine-kinase
MAASPAPRPAPPKPTSAPPRPTWDPRRPPQQAWLRPTIRIRLTLLYGGMFLIAGILLLSIIYLLAAQAVHVGNELPFQVTSGTFTIYSDACPALSGRRFTSSGAFNDAMKLCIDHQRQQALDDLLSRSLLALVGLSVIAFAFGYAMAGRVLAPLGRITRTARSVAGSDLSRRIELDGPDDELKELADTFDDMLDRLERAFTAQQRFVANASHELRTPLAINRTLLEVQLSDPGAPPELQQLGKTLLATNERSEQLVEGLLLLARSDNQIVERKPVDLGEVATRAVEQVRGEAEQREVELRADIAEAVVQGNGVLLERIALNLTQNAVRYNLPPGEGGWVEVSTELQHGQAVLVVTNTGPVVPAYEIDQLFEPFRRLRTERTGSDKGVGLGLSIVRSVTRAHGGRITAEPREGGGLVMRVTLPL
>NZ_CP014485.1|WP_033240980.1|1474656_1475310_-|response-regulator-transcription-factor
MRVLVVEDEQLLADAVATGLRREAMAVDVVYDGAAALERVGVNDYDVIVLDRDLPLVHGDDVCRKVVELQMPTRVLMLTASGDVSDRVEGLEIGADDYLPKPFAFTELIARVRALGRRTSVPLPPVLERAGIKLDPNRREVFRDGREIQLAPKEFAVLEVLLRSEGAVVSAEQLLEKAWDENTDPFTNVVRVTVMTLRRKLGEPAVIVTVPGSGYRI
>NZ_CP014485.1|WP_010641647.1|1475908_1476718_-|inositol-monophosphatase
MTDPNTGLLALALEAARRAGDFLRDGRPADLAVAATKTSAIDVVTEMDIASEKMITGFLADRRPEDGFLGEEGASTEGTSGVRWIIDPLDGTVNYLYGRPAWAVSIAAERDGVTVVGVVHAPMRGETCRAVLGGGAHLDDTPIQVNTAPTLDRALVGTGFGYLAGRKAHQAAVAARIIPEVRDIRRGGSAAIDLCDVATGRLDAYYERGLNPWDYAAGELIAREAGALTGGRPGALASTELTVAAPPGLFEPLQERLEEYGAWHDGTLA
>NZ_CP014485.1|WP_008406645.1|1476751_1477867_-|ferrochelatase
MSDVRDATPYDALLLLSFGGPEGPDDVVPFLRNVTHGRGIPEERLKEVGQHYYLFDGISPINAQNRDLLAALRADFAEHGVELPVFWGNRNWSPYLPDTLREMAKEGHRRIAVLATSAYASYSGCRQYRENLADALAALQTEGLPVPRVDKLRHYFNHPGFLEPMIDGVLASLADLPEEVRDGAEIAFTTHSIPDAAADTSGPREVHGDGGAYVAQHLDTARVIADAVRERTGVDRPWSLVYQSRSGSPHIPWLEPDICDHLEERHAAGAPAVVMAPIGFVSDHMEVRYDLDTEATAKAAELGLPVRRSATVGADPRFAAAVRDLLLERAATERGEHPARCALGALGPSHDVCPVGCCPARSPRPAAAGLD
>NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter
MPSPYRAIFSAPGSRGFSAAGFVGRLPLSMMGIGIVTMISQLTGRYGLAGALSAMVALSAALIGPQISRLVDLHGQRRVLRPATLVALAAVSGLLLSAQFSLPDWTLFLFAAGIGAVPSIGSMVRARWAALYRDQPRQLHTAYSFESVVDEACFIFGPIVSIGLSTTWFPEAGPLLAAVFLAAGVFSLTAQRSTEPVPHPREHHTKGSALRSTGLQVLVGTFVATGAIFGAIDVVTVAFAEEQGHKGAASLVLATYAAGSCLAGVVFGLLHFGGAPARRWLLGVVAMGVSMIPLQLVGNLPFLAVALFVAGLCIAPTMITTMALVEQHVPRAKLTEGMTWVSTGLAVGVALGSSVSGWVIDAAGAKAGYWVPAAAGAAAVLVGFLGYRRLSSPAPQREGPDGRAADAGQHQDGESGTHQERDLA
>NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein
MDEQQTQGSTRTASPVRTRNGTWRNWAGTVAARPARETAPASAAELAGAVRDAAARGMRVKAVGTGHSFTAAAATDGLLIRPDLLTGIQIDHEAGTVTVAAGTPLKRLNVALAREGLSLTNMGDIMEQTVAGATSTGTHGTGRASASLSAQITGLELVTADGSLLSCSREQNPELFAAARIGLGALGVITSLTFAVEPVFLLRAREEPMGFDQVTAEFDQLVAENEHFEFYWFPHTGNCSTKRNNRTPGPAAPVGRLSGWFEDEFLSNGVFQAANTLGRAVPATIPSLARLSSRALSARTYTDIPYKVFTSPRRVRFVEMEYALPREALVPALRELRAMVDRSPLRVSFPVEVRTAPADDIALSTASGRETAYIAVHLYKGTPYQAYFTAAERIFTAHEGRPHWGKIHTRDAEYFAEVYPRFAEFTALRDRLDPDRLFGNDYLRRVLGD
>NZ_CP014485.1|WP_061404097.1|1480557_1481742_-|hypothetical-protein
MRETTQVKEVGTRSGEEPQEEAKRIDLSVPQVAGSAVAAVAGAVAASQLGVYGTVIGAGVMSVVATTGGSVFQHLFRRTGEQIRDVAHVRPKGEPGPDVPDTFRADPEPDPLTDPAPGRVASADPATAHTVPGDPPAPVEATQLLGRIDPAAPRPADAEATQLLGQADPEATQLLSQADPGATQLLGQAGPDATRALRVPAADPAEADQATRLLRAVPEPSGPETGEFGEATTHQARTGRWKRPLISAAAVFVLAMGGITGWELVSGHALSGDSGPTISHLTGNRSQPSGDQEEEKAPAPEETPSGEAPSDGGSGAPSTQDPEDGTSSTGTPEEGTSPAPTRPGQQPGTPDDSTGDRSPTPTPTPSAGEPEQPTGQPSGGVPSGAAPEEDAPAG
>NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein
MPELRVVAVSNDGTRLVLKAADSTEYTLPIDERLRAAVRGDRPRLGQIEIEVESHLRPRDIQARIRAGASAEEVASLAGIPVDRVRRFEGPVLAERAFMAERARKTPVRRPGENTGPQLGEAVRERLLLRGADRDTVQWDSWRRDDGTWEVLLVYGVAGERHSASWSYDPPRRLVQAVDDEARSLIGESDDVSAPEPSFPFVPRIARLPRERPERPERGPHAVEPETEELPATAEQGGRDSLTSLLEAVPSFRGDMVVPERPAAERPLEEPEQEQEAEEPPAPAASAGSAYADVLMPRAVAAHRDRLIGSTDRQAEADGVRPGRRAAVPSWDEIVFGTRRKNKE

Crispr_ID: NZ_CP014485_4

• CRISPR_ID: NZ_CP014485_4
• CRISPR_location: 1481181-1481326
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014485_4

Consensus_repeat	Method
GGCCCAGGAGCTGGGTGGCCTCG	CRISPRCasFinder

spacers of NZ_CP014485_4

>4.1|1481204|43|NZ_CP014485|CRISPRCasFinder
GGGTCTGCCTGACTCAGGAGCTGGGTCGCCTCCGGGTCGGCCT
>4.2|1481270|34|NZ_CP014485|CRISPRCasFinder
GCATCGGCGGGGCGCGGGGCGGCGGGATCGATCC

CRISPR arrays and Neighbor proteins around NZ_CP014485_4

CRISPR arrays

The CRISPR arrays of NZ_CP014485_4

>merge|NZ_CP014485|4|1481181-1481326|CRISPRCasFinder
GGCCGAGGAGCTGGGTCGCCCCGGGGTCTGCCTGACTCAGGAGCTGGGTCGCCTCCGGGTCGGCCTGGCCCAGGAGCTGGGTGGCCTCGGCATCGGCGGGGCGCGGGGCGGCGGGATCGATCCGGCCCAGGAGCTGGGTGGCCTCG

>NZ_CP014485|4|4|1481181-1481326|CRISPRCasFinder
GGCCGAGGAGCTGGGTCGCCCCG	GGGTCTGCCTGACTCAGGAGCTGGGTCGCCTCCGGGTCGGCCT
GGCCCAGGAGCTGGGTGGCCTCG	GCATCGGCGGGGCGCGGGGCGGCGGGATCGATCC
GGCCCAGGAGCTGGGTGGCCTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein	unknown	unknown	gnl|CDD|378619
NZ_CP014485.1|WP_003951317.1|1494180_1495572_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP014485.1|WP_079075963.1|1471740_1472676_-|hypothetical-protein	unknown	unknown	gnl|CDD|378945
NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein	unknown	unknown	gnl|CDD|281959
NZ_CP014485.1|WP_030770684.1|1485247_1486429_-|alkaline-phosphatase-family-protein	unknown	unknown	gnl|CDD|366747
NZ_CP014485.1|WP_008406645.1|1476751_1477867_-|ferrochelatase	unknown	unknown	gnl|CDD|234585
NZ_CP014485.1|WP_003951340.1|1470293_1470878_-|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_CP014485.1|WP_079075964.1|1490046_1490409_+|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|273389
NZ_CP014485.1|WP_008406633.1|1470935_1471394_+|DUF3093-domain-containing-protein	unknown	unknown	gnl|CDD|378627
NZ_CP014485.1|WP_061404100.1|1487100_1489980_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein	unknown	unknown	gnl|CDD|131764
NZ_CP014485.1|WP_008406666.1|1492087_1492774_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP014485.1|WP_003951337.1|1472688_1472985_-|DUF4193-domain-containing-protein	unknown	unknown	gnl|CDD|379391
NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP014485.1|WP_033240980.1|1474656_1475310_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP014485.1|WP_003951336.1|1473379_1474651_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP014485.1|WP_061404099.1|1484403_1485204_+|VOC-family-protein	unknown	unknown	gnl|CDD|319911
NZ_CP014485.1|WP_003951325.1|1486428_1487028_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_018469408.1|1492995_1493769_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP014485.1|WP_010641647.1|1475908_1476718_-|inositol-monophosphatase	unknown	unknown	gnl|CDD|238817
NZ_CP014485.1|WP_061404098.1|1483330_1484158_-|sulfurtransferase	unknown	unknown	gnl|CDD|225450

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein	gnl|CDD|378619	pfam11268, DUF3071, Protein of unknown function (DUF3071). Some members in this family of proteins are annotated as DNA-binding proteins however this cannot be confirmed. Currently no function is known.	3.71985e-61
NZ_CP014485.1|WP_003951317.1|1494180_1495572_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	6.13683e-60
NZ_CP014485.1|WP_079075963.1|1471740_1472676_-|hypothetical-protein	gnl|CDD|378945	pfam12787, EcsC, EcsC protein family. Proteins in this family are related to EcsC from B. subtilis. This protein is found in an operon with EcsA and EcsB which are components of an ABC transport system. The function of this protein is unknown.	0.000117094
NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein	gnl|CDD|281959	pfam04030, ALO, D-arabinono-1,4-lactone oxidase. This domain is specific to D-arabinono-1,4-lactone oxidase EC:1.1.3.-, which is involved in the final step of the D-erythroascorbic acid biosynthesis pathway.	7.96812e-116
NZ_CP014485.1|WP_030770684.1|1485247_1486429_-|alkaline-phosphatase-family-protein	gnl|CDD|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	9.86342e-40
NZ_CP014485.1|WP_008406645.1|1476751_1477867_-|ferrochelatase	gnl|CDD|234585	PRK00035, hemH, ferrochelatase; Reviewed.	1.8658e-128
NZ_CP014485.1|WP_003951340.1|1470293_1470878_-|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.00993e-11
NZ_CP014485.1|WP_079075964.1|1490046_1490409_+|HPr-family-phosphocarrier-protein	gnl|CDD|273389	TIGR01003, Phosphocarrier_protein_HPr, Phosphotransferase System HPr (HPr) Family. The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS].	5.00425e-20
NZ_CP014485.1|WP_008406633.1|1470935_1471394_+|DUF3093-domain-containing-protein	gnl|CDD|378627	pfam11292, DUF3093, Protein of unknown function (DUF3093). This family of proteins with unknown function appears to be restricted to Actinobacteria. Some members are annotated as alanine rich membrane proteins however this cannot be confirmed.	1.57638e-49
NZ_CP014485.1|WP_061404100.1|1487100_1489980_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein	gnl|CDD|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	4.18465e-105
NZ_CP014485.1|WP_008406666.1|1492087_1492774_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	4.24177e-41
NZ_CP014485.1|WP_003951337.1|1472688_1472985_-|DUF4193-domain-containing-protein	gnl|CDD|379391	pfam13834, DUF4193, Domain of unknown function (DUF4193). This domain of unknown function contains four conserved cysteines and a conserved histidine, including a CXXXXH motif.	1.90861e-60
NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.43622e-19
NZ_CP014485.1|WP_033240980.1|1474656_1475310_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.34314e-69
NZ_CP014485.1|WP_003951336.1|1473379_1474651_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.86374e-51
NZ_CP014485.1|WP_061404099.1|1484403_1485204_+|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.1996e-30
NZ_CP014485.1|WP_018469408.1|1492995_1493769_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	4.89112e-36
NZ_CP014485.1|WP_010641647.1|1475908_1476718_-|inositol-monophosphatase	gnl|CDD|238817	cd01639, IMPase, IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria.	3.32006e-97
NZ_CP014485.1|WP_061404098.1|1483330_1484158_-|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.75196e-82

Protein sequences

>NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein
MDEQQTQGSTRTASPVRTRNGTWRNWAGTVAARPARETAPASAAELAGAVRDAAARGMRVKAVGTGHSFTAAAATDGLLIRPDLLTGIQIDHEAGTVTVAAGTPLKRLNVALAREGLSLTNMGDIMEQTVAGATSTGTHGTGRASASLSAQITGLELVTADGSLLSCSREQNPELFAAARIGLGALGVITSLTFAVEPVFLLRAREEPMGFDQVTAEFDQLVAENEHFEFYWFPHTGNCSTKRNNRTPGPAAPVGRLSGWFEDEFLSNGVFQAANTLGRAVPATIPSLARLSSRALSARTYTDIPYKVFTSPRRVRFVEMEYALPREALVPALRELRAMVDRSPLRVSFPVEVRTAPADDIALSTASGRETAYIAVHLYKGTPYQAYFTAAERIFTAHEGRPHWGKIHTRDAEYFAEVYPRFAEFTALRDRLDPDRLFGNDYLRRVLGD
>NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter
MPSPYRAIFSAPGSRGFSAAGFVGRLPLSMMGIGIVTMISQLTGRYGLAGALSAMVALSAALIGPQISRLVDLHGQRRVLRPATLVALAAVSGLLLSAQFSLPDWTLFLFAAGIGAVPSIGSMVRARWAALYRDQPRQLHTAYSFESVVDEACFIFGPIVSIGLSTTWFPEAGPLLAAVFLAAGVFSLTAQRSTEPVPHPREHHTKGSALRSTGLQVLVGTFVATGAIFGAIDVVTVAFAEEQGHKGAASLVLATYAAGSCLAGVVFGLLHFGGAPARRWLLGVVAMGVSMIPLQLVGNLPFLAVALFVAGLCIAPTMITTMALVEQHVPRAKLTEGMTWVSTGLAVGVALGSSVSGWVIDAAGAKAGYWVPAAAGAAAVLVGFLGYRRLSSPAPQREGPDGRAADAGQHQDGESGTHQERDLA
>NZ_CP014485.1|WP_008406645.1|1476751_1477867_-|ferrochelatase
MSDVRDATPYDALLLLSFGGPEGPDDVVPFLRNVTHGRGIPEERLKEVGQHYYLFDGISPINAQNRDLLAALRADFAEHGVELPVFWGNRNWSPYLPDTLREMAKEGHRRIAVLATSAYASYSGCRQYRENLADALAALQTEGLPVPRVDKLRHYFNHPGFLEPMIDGVLASLADLPEEVRDGAEIAFTTHSIPDAAADTSGPREVHGDGGAYVAQHLDTARVIADAVRERTGVDRPWSLVYQSRSGSPHIPWLEPDICDHLEERHAAGAPAVVMAPIGFVSDHMEVRYDLDTEATAKAAELGLPVRRSATVGADPRFAAAVRDLLLERAATERGEHPARCALGALGPSHDVCPVGCCPARSPRPAAAGLD
>NZ_CP014485.1|WP_010641647.1|1475908_1476718_-|inositol-monophosphatase
MTDPNTGLLALALEAARRAGDFLRDGRPADLAVAATKTSAIDVVTEMDIASEKMITGFLADRRPEDGFLGEEGASTEGTSGVRWIIDPLDGTVNYLYGRPAWAVSIAAERDGVTVVGVVHAPMRGETCRAVLGGGAHLDDTPIQVNTAPTLDRALVGTGFGYLAGRKAHQAAVAARIIPEVRDIRRGGSAAIDLCDVATGRLDAYYERGLNPWDYAAGELIAREAGALTGGRPGALASTELTVAAPPGLFEPLQERLEEYGAWHDGTLA
>NZ_CP014485.1|WP_033240980.1|1474656_1475310_-|response-regulator-transcription-factor
MRVLVVEDEQLLADAVATGLRREAMAVDVVYDGAAALERVGVNDYDVIVLDRDLPLVHGDDVCRKVVELQMPTRVLMLTASGDVSDRVEGLEIGADDYLPKPFAFTELIARVRALGRRTSVPLPPVLERAGIKLDPNRREVFRDGREIQLAPKEFAVLEVLLRSEGAVVSAEQLLEKAWDENTDPFTNVVRVTVMTLRRKLGEPAVIVTVPGSGYRI
>NZ_CP014485.1|WP_003951336.1|1473379_1474651_-|HAMP-domain-containing-histidine-kinase
MAASPAPRPAPPKPTSAPPRPTWDPRRPPQQAWLRPTIRIRLTLLYGGMFLIAGILLLSIIYLLAAQAVHVGNELPFQVTSGTFTIYSDACPALSGRRFTSSGAFNDAMKLCIDHQRQQALDDLLSRSLLALVGLSVIAFAFGYAMAGRVLAPLGRITRTARSVAGSDLSRRIELDGPDDELKELADTFDDMLDRLERAFTAQQRFVANASHELRTPLAINRTLLEVQLSDPGAPPELQQLGKTLLATNERSEQLVEGLLLLARSDNQIVERKPVDLGEVATRAVEQVRGEAEQREVELRADIAEAVVQGNGVLLERIALNLTQNAVRYNLPPGEGGWVEVSTELQHGQAVLVVTNTGPVVPAYEIDQLFEPFRRLRTERTGSDKGVGLGLSIVRSVTRAHGGRITAEPREGGGLVMRVTLPL
>NZ_CP014485.1|WP_003951337.1|1472688_1472985_-|DUF4193-domain-containing-protein
MATDYDTPRKTDDDLNEDSIEELKARRNDKSTSTVDVDEFEAAEGLELPGADLSNEELAVRVLPKQQDEFTCMSCFLVHHRSQLAREKNGQPICRDCD
>NZ_CP014485.1|WP_079075963.1|1471740_1472676_-|hypothetical-protein
MTGTTPPRKFPFLKRRGDGAPSPAESDGERGLGASLEAADATDGAPGPHSGGSGTGEGPAATEPATPAPGRVAAVRDGLLRQGRNAKAGLGVLADRVIEIAPRIPVRDLHTLRAQFPGLGPEQLADKLISGAAHGTSTVGASVGAAAMLPVPPAMPAELAAEITAVAAIELKLIAELHEVYGQRPEGGATRRATAYLTSWTNERGIDVVRPLTITAALSGPLKRDLRQQITKRMIRNLPNLVPFLVGAAVGAVMNRRDTRKLAERVRQDLRVAQVPWDQLTSLPPLDRPELPPATLPHALPPAPRDDNRPT
>NZ_CP014485.1|WP_008406633.1|1470935_1471394_+|DUF3093-domain-containing-protein
MHPNTPQYAERLTAPRAWWALVAIAGLTSGLIVMPLGVLAMLIGLVVGAAAGAAGLSTYGSAQIRVVGDALVAGDARIPLSALGAAEPLDAEETVAWRSHKADPRAFMLLRSYIPTAVRVEVTDPADPTPYLYLSTRDPERLAAALSPVREG
>NZ_CP014485.1|WP_003951340.1|1470293_1470878_-|PaaI-family-thioesterase
MSGRTPALTPPDSALAPVRHPDAPAPGEPIGTHYEHCFGCGGEQPHGLHLAAKAGEGVSVTAEFLVRPEHQGAPGLAHGGLLATALDDTLGALNWLLRVISVTGRLETDYLRPVPVGTVLHLSAEVTAVDGRKIYATAEGRLNAPDGPVAVRADALFVEVKVEHFTDNGRPEEIQAAMDDPDQIRRVRAFEVNP
>NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein
MPELRVVAVSNDGTRLVLKAADSTEYTLPIDERLRAAVRGDRPRLGQIEIEVESHLRPRDIQARIRAGASAEEVASLAGIPVDRVRRFEGPVLAERAFMAERARKTPVRRPGENTGPQLGEAVRERLLLRGADRDTVQWDSWRRDDGTWEVLLVYGVAGERHSASWSYDPPRRLVQAVDDEARSLIGESDDVSAPEPSFPFVPRIARLPRERPERPERGPHAVEPETEELPATAEQGGRDSLTSLLEAVPSFRGDMVVPERPAAERPLEEPEQEQEAEEPPAPAASAGSAYADVLMPRAVAAHRDRLIGSTDRQAEADGVRPGRRAAVPSWDEIVFGTRRKNKE
>NZ_CP014485.1|WP_061404098.1|1483330_1484158_-|sulfurtransferase
MNAIISATALAGELQGPRPPVLLDVRWQLGGPDQRPAYLAGHLPGAVHVDLDGELAGGPGKGGRHPLPDVEAFGAAMRAAGVDAGRPVVTYDGGQGWAAARAWWLLRWAGHPEVRVLDGGLAAWDGPLEEGEVTPEPGDFTPEPGRLELLDADGAAALAASGVLLDARAAERYRGDVEPIDRVGGHIPGAVSAPTTENTGEDGRLLPAAELADRFAALGANPGRKVGVYCGSGVSGAHEVLALAVAGVDAALYVGSWSDWSADPDRPVATGPQPG
>NZ_CP014485.1|WP_061404099.1|1484403_1485204_+|VOC-family-protein
MSAVRGQTVDQRTERPVPGTPCWVSLMADDPVASQEFYGRLFGWEFRPGPEQLGPYARALLDGRVVAGIGRMPEGQSLPVAWTPYLAADDVDETAGTVRHCGGTVGVGPLDAEEAGRMALAADPSGATFGIWQGREHRGAAVEGVPGSVLWNELVTRETAGVLPFYRAAFGFEAEREEGAEDAATLLLDGRPVASVLGVGQALGELGAAHWHTHFAVEDPDETVNRVIELGGRVQRPPRDGSHGRTATVADPWGAVFTVARPDTRA
>NZ_CP014485.1|WP_030770684.1|1485247_1486429_-|alkaline-phosphatase-family-protein
MPSSAWPEPLPLASAPVPAYGSGSLADLLPTLAAGSGVPGMTATLTELPPADRNCVFLIDGLGWHQLLAHPAEAPFLSSLIPTSRGGTGQPLTAGFPATTATSLASVGTGRTPGEHGLPGYTALNPDSGELMNQLRWKPWTDPHAWQPHPTVFSLADAAGVHTAQVSAPGFHHTPLTQVALSGGTFHGRLSGEERMDLAAAQLAAGDRALVYTYYSEVDGKGHRFGVDSDAWRGQLMYVDGLARRLAEQLPPRSALYITADHGMVDIPFDDRHRFDVDEDWELNAGIRLLGGEGRARHLYAVPGAARDVRTVWREVLGEQCWVAGRDEAIEAGWFGPHVEKRVRDRLGDVIVAARDDVAITATRREPNESALTGMHGSMTPAEQLVPLLEVRT
>NZ_CP014485.1|WP_003951325.1|1486428_1487028_-|hypothetical-protein
MAKTGTTTQGLRAAIERSGYYPALVAEAVEAAVGGEPVASYLVHQETTFDANEVRRHVTVLVLTPTRFIVSHTDEQAADSGSPTALATTSTESVKTGRISSVVLSRVVANPESYTPGTLPREVVLTIGWGAVSRIDLEPAACGDPNCEADHGYTGSSTADDLSLRVSEAGDGPDTVRQALAFAQALSEATAATATPAGR
>NZ_CP014485.1|WP_061404100.1|1487100_1489980_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein
MDTPSDQHAYPAHWEADVVLRDGGTARIRPITADDADRLVSFYEQVSDESKYYRFFAPYPRLSAKDVRRFTHHDHVDRVGLAVTIGGEFIATVRYDRIDDRGMPASAPADEAEVAFLVQDAHQGRGVASALLEHIAAVARERGIRRFTAEVLPANTKMIKVFTDAGYQQKRSFEDGVVRLEFGLEPTDRSLAVQHAREQRAEARSVQRLLAPGSVAVVGVGRTLGGVGRSILRNIREAGFTGPVHAVNQGFPDTGDTVEGVRAHRSVRDIAEPVDLAVIAVPAERVPEAVAECGEHGVQGLVVISAGYAEQGPEGRERQRALIRQARSYGMRVIGPNAFGVINTTPETRLNASLAPELPVPGRVGLFTQSGAIGIALLSALHRDGGGADGVPNPTGVSTFVSAGNRADVSGNDVMQYWYDDPHTDVALMYLETIGNPRKFTRLARRTAAAKPLVVVQGARHSGITPTGHPAPVTRLPYATVSALLRQAGVIRVDTVTELVDVGLLLAGQPLPAGPRVAILGNSESLGLLSYDACLSQGLRPLPPRDLTTDATPEDFRAALAAALADDGCDAVVVTAIPWVGADGVPERPDGEALGAALRTAHATAPDKPVVVVHVELGGLAEALSAAAGTGPGSPATQRGPAPSPAAPDSAAPAPDEAPPVPRTRRIPAYPAAERAVRALGEAVRYAQWRREAQRPGGVPEYESIDERGAAADITRLLVAAAPGEEGAAPRAHTLGAEDTRALLARYGIEVRPTLPAPDPDTAVRAAAELGYPVALKTTAPHLRHRADLGGVRLDLADEAQLRQAYAELTGLFGTPAELRPVVQPMAPRGVDTVVRTVIDPAVGAVLTFGLAGAPSELLGDTAHRLVPVTDRDATAMVRSIRTAPLLFGWRGSAPVDTPALEELLQRVSRLVDDHPEVVDVQLEPVVVAPRGVSVLGASVRLAPPPARDDLGPRTLPAY
>NZ_CP014485.1|WP_079075964.1|1490046_1490409_+|HPr-family-phosphocarrier-protein
MSLAGSSGAVCESGLDNIVRFVKGSFNMAERRVNVGWAEGLHARPAFIFVRAATASGIPVTIAKPDTAPVKAASMLAVLGLGVQGGEEIVLSADAEGAEATLERLAKLVAEGLDELPETV
>NZ_CP014485.1|WP_008406666.1|1492087_1492774_-|GntR-family-transcriptional-regulator
MGIPAQSVCTAIREDIVSGVHERGSRLTEEQLARRYGVSRVPVREALRTLEAEGFVVTRRHAGACVAEPTEQEAADLLEIRMLLEPLGAARAARRRTEAHLKVLRGLVRLGQERARLGEGEDLRSLGAWFHETLAQASGSPGLTALLTQLRQKVTWMYAVDPPAAPAESWAEHGAIVDAVARGDAERARALTAQHAERATAVHRLRFGSRTTGVRTSQHAVNIPGGRN
>NZ_CP014485.1|WP_018469408.1|1492995_1493769_-|M23-family-metallopeptidase
MAFTRPTGKHRRPHRRAARTGAGLAGVAALTTTGVVSTLASPAAAAEAPAHTGFTEAIVIGHSLADRIDDQAAAQRLAAEDAAAEQAAVEAARLQAAEAKRKAEKKRAEKVRAARAAERERLNRYVLPVEGSYVSTGYQTGGSLWSSGSHSGVDFHAPAGSAVRAVGAGTVVETGWGGAYGNEVVIQMHDGTYTQYGHLASATVSVGQTVTPGQQIAVSGSTGNSTGPHLHFEARSGADYGTDMDPVAYLRGHGVDV
>NZ_CP014485.1|WP_003951317.1|1494180_1495572_-|insulinase-family-protein
MSDVITPAMDLHPQPAGGAPRPWAFPAPERTTLDNGLTVLTCHRPGQQVVAVEVLLDSPLDTEPEGLDGLATIMARAFSEGTDRDSAEEFAAELERCGATLDAFADHPGVRLSLEVPVSRLEKALGLLADALRAPAFAEAEIERLVRNRLDEIPHEQANPARRAAKELSRQLFPAGSRVSRPRQGTEETVERIDAAAVRAFYERHVRPATATAVIVGDLEGTDLGALLAGSLGAWQGDAGQPNPVPPVTADDTGRVVIVDRPGAVQTQLLIGRVGPDRHDRVWPAQVLGTYSLGGTLTSRLDRVLREEKGYTYGVRSFAQVLRSTPEGTGAAMLAISGSVDTESTGPALDDLWKVLRTLAAEGLTDAELDTAVQNLVGVAPLKYETAAAVASTLADQVEQHLPDDFQARLYRMMTETGATEATAAVVSAFPADRLVTVLVGDASRIAEPVRALGIGEVSVVTG

Crispr_ID: NZ_CP014485_5

• CRISPR_ID: NZ_CP014485_5
• CRISPR_location: 1490998-1491148
• CRISPR_type: Orphan
• Repeat_type: I-C,I-E,II-B
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014485_5

Consensus_repeat	Method
GGGTCCACCCCCGCACGTGCGGGGAACAG	CRISPRCasFinder

spacers of NZ_CP014485_5

>5.1|1491027|32|NZ_CP014485|CRISPRCasFinder
AAGCCGACCCAGCTCATGCTCTACGGCAAGAC
>5.2|1491088|32|NZ_CP014485|CRISPRCasFinder
CACGACGAGCGCGAGGCTCAGCGCCTCGTCTG

CRISPR arrays and Neighbor proteins around NZ_CP014485_5

CRISPR arrays

The CRISPR arrays of NZ_CP014485_5

>merge|NZ_CP014485|5|1490998-1491148|CRISPRCasFinder
GGCTCGCCCCCGCCGCGTGCGGGGAGCAGAAGCCGACCCAGCTCATGCTCTACGGCAAGACGGGTCCACCCCCGCACGTGCGGGGAACAGCACGACGAGCGCGAGGCTCAGCGCCTCGTCTGGGGTCCACCCCCGCACGTGCGGGGAACAG

>NZ_CP014485|5|5|1490998-1491148|CRISPRCasFinder
GGCTCGCCCCCGCCGCGTGCGGGGAGCAG	AAGCCGACCCAGCTCATGCTCTACGGCAAGAC
GGGTCCACCCCCGCACGTGCGGGGAACAG	CACGACGAGCGCGAGGCTCAGCGCCTCGTCTG
GGGTCCACCCCCGCACGTGCGGGGAACAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_037843948.1|1495564_1496929_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP014485.1|WP_061404097.1|1480557_1481742_-|hypothetical-protein	unknown	unknown	gnl|CDD|223039
NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein	unknown	unknown	gnl|CDD|378619
NZ_CP014485.1|WP_003951317.1|1494180_1495572_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein	unknown	unknown	gnl|CDD|281959
NZ_CP014485.1|WP_030770684.1|1485247_1486429_-|alkaline-phosphatase-family-protein	unknown	unknown	gnl|CDD|366747
NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP014485.1|WP_061404099.1|1484403_1485204_+|VOC-family-protein	unknown	unknown	gnl|CDD|319911
NZ_CP014485.1|WP_079075964.1|1490046_1490409_+|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|273389
NZ_CP014485.1|WP_030310486.1|1500884_1502480_-|glycoside-hydrolase-family-13-protein	unknown	unknown	gnl|CDD|200471
NZ_CP014485.1|WP_008406671.1|1499655_1500774_-|GTP-binding-protein	unknown	unknown	gnl|CDD|223597
NZ_CP014485.1|WP_003951312.1|1502517_1503393_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP014485.1|WP_008406666.1|1492087_1492774_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP014485.1|WP_030310488.1|1503403_1504366_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP014485.1|WP_030310490.1|1504368_1505778_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270451
NZ_CP014485.1|WP_061404100.1|1487100_1489980_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein	unknown	unknown	gnl|CDD|131764
NZ_CP014485.1|WP_003951325.1|1486428_1487028_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008406669.1|1497126_1499574_+|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl|CDD|235503
NZ_CP014485.1|WP_018469408.1|1492995_1493769_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP014485.1|WP_061404098.1|1483330_1484158_-|sulfurtransferase	unknown	unknown	gnl|CDD|225450

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_037843948.1|1495564_1496929_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.48874e-75
NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein	gnl|CDD|378619	pfam11268, DUF3071, Protein of unknown function (DUF3071). Some members in this family of proteins are annotated as DNA-binding proteins however this cannot be confirmed. Currently no function is known.	3.71985e-61
NZ_CP014485.1|WP_003951317.1|1494180_1495572_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	6.13683e-60
NZ_CP014485.1|WP_061404098.1|1483330_1484158_-|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.75196e-82
NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein	gnl|CDD|281959	pfam04030, ALO, D-arabinono-1,4-lactone oxidase. This domain is specific to D-arabinono-1,4-lactone oxidase EC:1.1.3.-, which is involved in the final step of the D-erythroascorbic acid biosynthesis pathway.	7.96812e-116
NZ_CP014485.1|WP_030770684.1|1485247_1486429_-|alkaline-phosphatase-family-protein	gnl|CDD|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	9.86342e-40
NZ_CP014485.1|WP_061404097.1|1480557_1481742_-|hypothetical-protein	gnl|CDD|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	9.08461e-05
NZ_CP014485.1|WP_079075964.1|1490046_1490409_+|HPr-family-phosphocarrier-protein	gnl|CDD|273389	TIGR01003, Phosphocarrier_protein_HPr, Phosphotransferase System HPr (HPr) Family. The HPr family are bacterial proteins (or domains of proteins) which function in phosphoryl transfer system (PTS) systems. They include energy-coupling components which catalyze sugar uptake via a group translocation mechanism. The functions of most of these proteins are not known, but they presumably function in PTS-related regulatory capacities. All seed members are stand-alone HPr proteins, although the model also recognizes HPr domains of PTS fusion proteins. This family includes the related NPr protein. [Signal transduction, PTS].	5.00425e-20
NZ_CP014485.1|WP_030310486.1|1500884_1502480_-|glycoside-hydrolase-family-13-protein	gnl|CDD|200471	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Trehalose synthase (EC 5.4.99.16) catalyzes the isomerization of maltose to produce trehalulose. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP014485.1|WP_008406671.1|1499655_1500774_-|GTP-binding-protein	gnl|CDD|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	3.22567e-66
NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.43622e-19
NZ_CP014485.1|WP_008406666.1|1492087_1492774_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	4.24177e-41
NZ_CP014485.1|WP_003951312.1|1502517_1503393_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.87658e-65
NZ_CP014485.1|WP_030310490.1|1504368_1505778_-|extracellular-solute-binding-protein	gnl|CDD|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.46535e-45
NZ_CP014485.1|WP_061404099.1|1484403_1485204_+|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.1996e-30
NZ_CP014485.1|WP_030310488.1|1503403_1504366_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.24826e-74
NZ_CP014485.1|WP_008406669.1|1497126_1499574_+|DNA-topoisomerase-IV-subunit-A	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
NZ_CP014485.1|WP_018469408.1|1492995_1493769_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	4.89112e-36
NZ_CP014485.1|WP_061404100.1|1487100_1489980_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein	gnl|CDD|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	4.18465e-105

Protein sequences

>NZ_CP014485.1|WP_079075964.1|1490046_1490409_+|HPr-family-phosphocarrier-protein
MSLAGSSGAVCESGLDNIVRFVKGSFNMAERRVNVGWAEGLHARPAFIFVRAATASGIPVTIAKPDTAPVKAASMLAVLGLGVQGGEEIVLSADAEGAEATLERLAKLVAEGLDELPETV
>NZ_CP014485.1|WP_061404100.1|1487100_1489980_-|bifunctional-GNAT-family-N-acetyltransferase/acetate--CoA-ligase-family-protein
MDTPSDQHAYPAHWEADVVLRDGGTARIRPITADDADRLVSFYEQVSDESKYYRFFAPYPRLSAKDVRRFTHHDHVDRVGLAVTIGGEFIATVRYDRIDDRGMPASAPADEAEVAFLVQDAHQGRGVASALLEHIAAVARERGIRRFTAEVLPANTKMIKVFTDAGYQQKRSFEDGVVRLEFGLEPTDRSLAVQHAREQRAEARSVQRLLAPGSVAVVGVGRTLGGVGRSILRNIREAGFTGPVHAVNQGFPDTGDTVEGVRAHRSVRDIAEPVDLAVIAVPAERVPEAVAECGEHGVQGLVVISAGYAEQGPEGRERQRALIRQARSYGMRVIGPNAFGVINTTPETRLNASLAPELPVPGRVGLFTQSGAIGIALLSALHRDGGGADGVPNPTGVSTFVSAGNRADVSGNDVMQYWYDDPHTDVALMYLETIGNPRKFTRLARRTAAAKPLVVVQGARHSGITPTGHPAPVTRLPYATVSALLRQAGVIRVDTVTELVDVGLLLAGQPLPAGPRVAILGNSESLGLLSYDACLSQGLRPLPPRDLTTDATPEDFRAALAAALADDGCDAVVVTAIPWVGADGVPERPDGEALGAALRTAHATAPDKPVVVVHVELGGLAEALSAAAGTGPGSPATQRGPAPSPAAPDSAAPAPDEAPPVPRTRRIPAYPAAERAVRALGEAVRYAQWRREAQRPGGVPEYESIDERGAAADITRLLVAAAPGEEGAAPRAHTLGAEDTRALLARYGIEVRPTLPAPDPDTAVRAAAELGYPVALKTTAPHLRHRADLGGVRLDLADEAQLRQAYAELTGLFGTPAELRPVVQPMAPRGVDTVVRTVIDPAVGAVLTFGLAGAPSELLGDTAHRLVPVTDRDATAMVRSIRTAPLLFGWRGSAPVDTPALEELLQRVSRLVDDHPEVVDVQLEPVVVAPRGVSVLGASVRLAPPPARDDLGPRTLPAY
>NZ_CP014485.1|WP_003951325.1|1486428_1487028_-|hypothetical-protein
MAKTGTTTQGLRAAIERSGYYPALVAEAVEAAVGGEPVASYLVHQETTFDANEVRRHVTVLVLTPTRFIVSHTDEQAADSGSPTALATTSTESVKTGRISSVVLSRVVANPESYTPGTLPREVVLTIGWGAVSRIDLEPAACGDPNCEADHGYTGSSTADDLSLRVSEAGDGPDTVRQALAFAQALSEATAATATPAGR
>NZ_CP014485.1|WP_030770684.1|1485247_1486429_-|alkaline-phosphatase-family-protein
MPSSAWPEPLPLASAPVPAYGSGSLADLLPTLAAGSGVPGMTATLTELPPADRNCVFLIDGLGWHQLLAHPAEAPFLSSLIPTSRGGTGQPLTAGFPATTATSLASVGTGRTPGEHGLPGYTALNPDSGELMNQLRWKPWTDPHAWQPHPTVFSLADAAGVHTAQVSAPGFHHTPLTQVALSGGTFHGRLSGEERMDLAAAQLAAGDRALVYTYYSEVDGKGHRFGVDSDAWRGQLMYVDGLARRLAEQLPPRSALYITADHGMVDIPFDDRHRFDVDEDWELNAGIRLLGGEGRARHLYAVPGAARDVRTVWREVLGEQCWVAGRDEAIEAGWFGPHVEKRVRDRLGDVIVAARDDVAITATRREPNESALTGMHGSMTPAEQLVPLLEVRT
>NZ_CP014485.1|WP_061404099.1|1484403_1485204_+|VOC-family-protein
MSAVRGQTVDQRTERPVPGTPCWVSLMADDPVASQEFYGRLFGWEFRPGPEQLGPYARALLDGRVVAGIGRMPEGQSLPVAWTPYLAADDVDETAGTVRHCGGTVGVGPLDAEEAGRMALAADPSGATFGIWQGREHRGAAVEGVPGSVLWNELVTRETAGVLPFYRAAFGFEAEREEGAEDAATLLLDGRPVASVLGVGQALGELGAAHWHTHFAVEDPDETVNRVIELGGRVQRPPRDGSHGRTATVADPWGAVFTVARPDTRA
>NZ_CP014485.1|WP_061404098.1|1483330_1484158_-|sulfurtransferase
MNAIISATALAGELQGPRPPVLLDVRWQLGGPDQRPAYLAGHLPGAVHVDLDGELAGGPGKGGRHPLPDVEAFGAAMRAAGVDAGRPVVTYDGGQGWAAARAWWLLRWAGHPEVRVLDGGLAAWDGPLEEGEVTPEPGDFTPEPGRLELLDADGAAALAASGVLLDARAAERYRGDVEPIDRVGGHIPGAVSAPTTENTGEDGRLLPAAELADRFAALGANPGRKVGVYCGSGVSGAHEVLALAVAGVDAALYVGSWSDWSADPDRPVATGPQPG
>NZ_CP014485.1|WP_008406653.1|1482219_1483254_+|DUF3071-domain-containing-protein
MPELRVVAVSNDGTRLVLKAADSTEYTLPIDERLRAAVRGDRPRLGQIEIEVESHLRPRDIQARIRAGASAEEVASLAGIPVDRVRRFEGPVLAERAFMAERARKTPVRRPGENTGPQLGEAVRERLLLRGADRDTVQWDSWRRDDGTWEVLLVYGVAGERHSASWSYDPPRRLVQAVDDEARSLIGESDDVSAPEPSFPFVPRIARLPRERPERPERGPHAVEPETEELPATAEQGGRDSLTSLLEAVPSFRGDMVVPERPAAERPLEEPEQEQEAEEPPAPAASAGSAYADVLMPRAVAAHRDRLIGSTDRQAEADGVRPGRRAAVPSWDEIVFGTRRKNKE
>NZ_CP014485.1|WP_061404097.1|1480557_1481742_-|hypothetical-protein
MRETTQVKEVGTRSGEEPQEEAKRIDLSVPQVAGSAVAAVAGAVAASQLGVYGTVIGAGVMSVVATTGGSVFQHLFRRTGEQIRDVAHVRPKGEPGPDVPDTFRADPEPDPLTDPAPGRVASADPATAHTVPGDPPAPVEATQLLGRIDPAAPRPADAEATQLLGQADPEATQLLSQADPGATQLLGQAGPDATRALRVPAADPAEADQATRLLRAVPEPSGPETGEFGEATTHQARTGRWKRPLISAAAVFVLAMGGITGWELVSGHALSGDSGPTISHLTGNRSQPSGDQEEEKAPAPEETPSGEAPSDGGSGAPSTQDPEDGTSSTGTPEEGTSPAPTRPGQQPGTPDDSTGDRSPTPTPTPSAGEPEQPTGQPSGGVPSGAAPEEDAPAG
>NZ_CP014485.1|WP_061404096.1|1479187_1480537_+|FAD-binding-protein
MDEQQTQGSTRTASPVRTRNGTWRNWAGTVAARPARETAPASAAELAGAVRDAAARGMRVKAVGTGHSFTAAAATDGLLIRPDLLTGIQIDHEAGTVTVAAGTPLKRLNVALAREGLSLTNMGDIMEQTVAGATSTGTHGTGRASASLSAQITGLELVTADGSLLSCSREQNPELFAAARIGLGALGVITSLTFAVEPVFLLRAREEPMGFDQVTAEFDQLVAENEHFEFYWFPHTGNCSTKRNNRTPGPAAPVGRLSGWFEDEFLSNGVFQAANTLGRAVPATIPSLARLSSRALSARTYTDIPYKVFTSPRRVRFVEMEYALPREALVPALRELRAMVDRSPLRVSFPVEVRTAPADDIALSTASGRETAYIAVHLYKGTPYQAYFTAAERIFTAHEGRPHWGKIHTRDAEYFAEVYPRFAEFTALRDRLDPDRLFGNDYLRRVLGD
>NZ_CP014485.1|WP_008406647.1|1477986_1479261_+|MFS-transporter
MPSPYRAIFSAPGSRGFSAAGFVGRLPLSMMGIGIVTMISQLTGRYGLAGALSAMVALSAALIGPQISRLVDLHGQRRVLRPATLVALAAVSGLLLSAQFSLPDWTLFLFAAGIGAVPSIGSMVRARWAALYRDQPRQLHTAYSFESVVDEACFIFGPIVSIGLSTTWFPEAGPLLAAVFLAAGVFSLTAQRSTEPVPHPREHHTKGSALRSTGLQVLVGTFVATGAIFGAIDVVTVAFAEEQGHKGAASLVLATYAAGSCLAGVVFGLLHFGGAPARRWLLGVVAMGVSMIPLQLVGNLPFLAVALFVAGLCIAPTMITTMALVEQHVPRAKLTEGMTWVSTGLAVGVALGSSVSGWVIDAAGAKAGYWVPAAAGAAAVLVGFLGYRRLSSPAPQREGPDGRAADAGQHQDGESGTHQERDLA
>NZ_CP014485.1|WP_008406666.1|1492087_1492774_-|GntR-family-transcriptional-regulator
MGIPAQSVCTAIREDIVSGVHERGSRLTEEQLARRYGVSRVPVREALRTLEAEGFVVTRRHAGACVAEPTEQEAADLLEIRMLLEPLGAARAARRRTEAHLKVLRGLVRLGQERARLGEGEDLRSLGAWFHETLAQASGSPGLTALLTQLRQKVTWMYAVDPPAAPAESWAEHGAIVDAVARGDAERARALTAQHAERATAVHRLRFGSRTTGVRTSQHAVNIPGGRN
>NZ_CP014485.1|WP_018469408.1|1492995_1493769_-|M23-family-metallopeptidase
MAFTRPTGKHRRPHRRAARTGAGLAGVAALTTTGVVSTLASPAAAAEAPAHTGFTEAIVIGHSLADRIDDQAAAQRLAAEDAAAEQAAVEAARLQAAEAKRKAEKKRAEKVRAARAAERERLNRYVLPVEGSYVSTGYQTGGSLWSSGSHSGVDFHAPAGSAVRAVGAGTVVETGWGGAYGNEVVIQMHDGTYTQYGHLASATVSVGQTVTPGQQIAVSGSTGNSTGPHLHFEARSGADYGTDMDPVAYLRGHGVDV
>NZ_CP014485.1|WP_003951317.1|1494180_1495572_-|insulinase-family-protein
MSDVITPAMDLHPQPAGGAPRPWAFPAPERTTLDNGLTVLTCHRPGQQVVAVEVLLDSPLDTEPEGLDGLATIMARAFSEGTDRDSAEEFAAELERCGATLDAFADHPGVRLSLEVPVSRLEKALGLLADALRAPAFAEAEIERLVRNRLDEIPHEQANPARRAAKELSRQLFPAGSRVSRPRQGTEETVERIDAAAVRAFYERHVRPATATAVIVGDLEGTDLGALLAGSLGAWQGDAGQPNPVPPVTADDTGRVVIVDRPGAVQTQLLIGRVGPDRHDRVWPAQVLGTYSLGGTLTSRLDRVLREEKGYTYGVRSFAQVLRSTPEGTGAAMLAISGSVDTESTGPALDDLWKVLRTLAAEGLTDAELDTAVQNLVGVAPLKYETAAAVASTLADQVEQHLPDDFQARLYRMMTETGATEATAAVVSAFPADRLVTVLVGDASRIAEPVRALGIGEVSVVTG
>NZ_CP014485.1|WP_037843948.1|1495564_1496929_-|insulinase-family-protein
MGDTATARAASGGLTATEHRLANGLRVVLSEDHLTPVAAVCLWYDVGSRHEVKGRTGLAHLFEHLMFQGSAQVKGNGHFELVQGAGGSLNGTTSFERTNYFETMPAHQLELALWLEADRMGTLLTALDDESMENQRDVVKNERRQRYDNVPYGTAFEKLTALAYPEGHPYHHTPIGSMADLDAATLEDAREFFRTYYAPNNAVLSVVGDIDPGQTLAWIEKYFGSIPGHEGKRPPRDGSLPDTIGSELREVVREEVPARALMAAYRLPEDGTRAADAADVALTVLGGGESSRLYNRLVRRDRSAVAAGFGLLRLAGAPSLGWLDVKASGDVEIPAIETAVDEELARFAAEGPTAEEMERAQAQLEREWLDRLGTVAGRADELCRYAVLFGDPQLALTAVGRVLDVTADEVRQAAAERLRPDNRAVLVYEPLTAEEAGPADQTETATGEEAAASE
>NZ_CP014485.1|WP_008406669.1|1497126_1499574_+|DNA-topoisomerase-IV-subunit-A
MARRSTKTPPPDDFEERILDIDVVDEMQGSFLEYAYSVIYSRALPDARDGMKPVHRRIVYQMNEMGLRRDRGYVKCARVVGEVMGKLHPHGDASIYDALVRMAQPFSMRLPLVDGHGNFGSLGNDDPPAAMRYTECRMADATSLMTESIDENTVDFSPNYDGQEQEPVALPAAFPNLLVNGASGIAVGMATNMPPHNLGEVVAAARHLIKHPGADLETLMRFVPGPDLPTGGRIVGLGGVRDAYATGRGTFKIRATVAVENVTARRKGLVVTELPFSVGPEKVISKIKDLVGAKKLQGIADVKDLTDREHGLRLVIEIKNGFVPEAVLEQLYKLTPMEESFGINNVALVDGQPLTLGLKELLEVYLDHRFTVVRRRSEFRRGKKRDRLHLVEGLLVALVDIDEVIRIIRDSENSAEARERLMERFSLSDIQTQYILDTPLRRLTRFDRIELESERDRLTAEIEELSRILDSDAELRKLVSSELAAVSKKYGTDRRTVLLESSGAAAAVPLQVEDTPCRVLLSSTGLLARTADATPLAEAPKRVKHDLIVSAVAATARGEVGAVTSAGRLLRLQVIDLPQLPGTDTTPSLSGGAPVAEFLTLEADERLVCLTTLDESSPGLALGTAQGVVKRVVPDYPSHKEELEVISLRDGDRIVGATELRTGEEDLVFITDEAHLLRFPASVVRPQGRPAGGMAGVKLGEGARVVSFTAVDPAVDAVVFTVAGSRGTLDDSVQTTAKVTPFDQYPRKGRATGGVRCQRFLKGEDCLSFAWAGPAPAHAAQRDGSPAPLPELDPRRDGSGLSLPKPVAAAAGPVG
>NZ_CP014485.1|WP_008406671.1|1499655_1500774_-|GTP-binding-protein
MGRQQIPVVVLAGFLGSGKTTLLNQLLWRSRGTRIGAVVNDFGAIEIDAMTVAGQVGSTVSLGNGCLCCAVDVAELDTYLERLTRPEAGLDVIVIEASGLAEPVELVRMILASENPHIRYGGLVEVVDAAEYEATRERHPELDRHLAAADLVVLNKTDRVTPAELAELLTAVRERAGDGAVTPASYGRIDPELLFDRRPQTERYGQLSFDDAREEDEPGGGREDHDDHDGHLHAAYDSASFTTGTPLHPRRLMDLLDARPEGLYRIKGFVDFGPLDPGHVYTLHAVGRFLRFAPRPWEPGEERRTQLVLIGAGIDPDALTAQLEGCRDAAREAEERHLWSVLRFVRAEEDTADPDDPEALRAAAPGTEQPVA
>NZ_CP014485.1|WP_030310486.1|1500884_1502480_-|glycoside-hydrolase-family-13-protein
MPDSDWWRSAVIYQVYVRSFADADGDGTGDLAGVRAKLPYLAQLGVDALWFNPWYASPMADGGYDVADYRAIHPSFGTLAEAEKLIEEAAGHGIRTIVDIVPNHVSEAHPWFRAALAEGPGGPSRDLFHFRPGRGEHGELAPNDWRSEFGGPAWTRLPDGEWYLHLFAPEQPDLNWAHPAVRTEHEEILRFWFERGVAGVRIDSAALPAKDPALPDFTPGQDPHPYLDRDELHDIYRSWRAVADRYGAVFVGEVWLPDSERFARYLRPDELHTAFNFAFLSCPWEPERLRAAIRDTLAEHAPVGAPATWVLCNHDITRTVTRYGRAETGFDFAAKRFGTPTDPVLGTRRARAAALLSLALPGATYLYQGEELGLPEAEIPREHIEDPMHARSGGVDPGRDGCRVPLPWTADAPHAGFSTGEPWLPQPSGWAAHAADLQDGDPASMLTLYRTALALRRATPGLGDGPLEWLESPEEVLAFRRPGGVLCLVNLGAGPVPVPEGTELLLASGALGADGALPSDTAVWLREPAAA
>NZ_CP014485.1|WP_003951312.1|1502517_1503393_-|carbohydrate-ABC-transporter-permease
MTTRTLISPARLSRPRGRILYWTVLFLVVAVFTLVFIGPLYWMVTSGLKDTEEFARIPPTLVPDAVHPGNYGEAWQVMELSQLLFNTLYYAFGALAFQLVLDVAAAYSLSKLRPVLGKAILGAMLVTLMIPATVLVVPQYLTVLDLPVFERNLLNTPWVIWLPSVTNAFNIFLLKRFFDSIPRELLDAAAIDGASPMRTLRSVVLPISRPILGVVSIFAVVGVWKDFLWPMLALPDPGKQTLNVGIYSLASGVPENWLLAALAMASLPTLILFLIFQRNIMSGLTAGGLKG
>NZ_CP014485.1|WP_030310488.1|1503403_1504366_-|sugar-ABC-transporter-permease
MAPPTSTPTLTRRPAGTDDGAPRVKEPRQGAFARAVRRNLTAHAFLIGAVLCFGFFSWYPMVREVVLAFQKTENGVVSWAGWSNFVYVFNDPDFALAWRNTALFTLLALLLGFVVPFVIALVLNEFRHARGYLRLLVYLPVMLPPVASVLLFKYFYDPGHGLFNRLLELFGLPAQQWLQSSDTAMLSLVIASTWMNMGGACLIYLAALQTIPGELYEAAELDGAGLLRKIWHVTIPQTRLILSLLFLMQIIATMQVFTEPFLLTGGAGPEGSTTTVVHLIYQYAFNFNNYGAAAALGLVLLVVLAGFSAAYVRLNRAEQE
>NZ_CP014485.1|WP_030310490.1|1504368_1505778_-|extracellular-solute-binding-protein
MRSSGFSTPHRRRTAVTFVSALTLLSLAACGTSSSGDQDPAPGGSADAATPLDPKTKLTLTIDCMPPAAKKAELKQWKEDVATFNKTYPNITIDGRSTPGQCLEPPRFTAMLKAKSQPDVFYAYFTDLDQVLDNDGAADISAYVNEKTVPALADIDPDVMKVLKKDDKLYALPTSNYRMGLLINRGLFEKAGLDPDTPPSTWEEVREAADKIAGLGKGIAGFGEYSAGNTGGWHYTATVYGEGGEIVGPDGKAAFNDATGKRVAQNLYDMRWKDDSMGKTQLLKWGDLQKQMATDKLGMFLAAPDDITYMVQQLGADYANFGMGPMPGQKATLFGGNSYMIKKGISSDKIKAAVAWLDLKTLSPGKGQFAWSRTKADGLPVGLPQPAFFTGAAKEQDDKERADHATMPVENFRAFTDNPVDGKAEPPKAQEVYKVLDTVMSTLLTNKDADIDKLLDTAEQQVNQVLANQ

Crispr_ID: NZ_CP014485_6

• CRISPR_ID: NZ_CP014485_6
• CRISPR_location: 1870661-1870762
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_6

Consensus_repeat	Method
CCAGCCCGGCCGGCGTTTGAGGCC	CRISPRCasFinder

spacers of NZ_CP014485_6

>6.1|1870685|54|NZ_CP014485|CRISPRCasFinder
ATCGGTGACCGCCACGGACGACCACCGGCACCGCAGGCCGAAGCCCGGCCACAA

CRISPR arrays and Neighbor proteins around NZ_CP014485_6

CRISPR arrays

The CRISPR arrays of NZ_CP014485_6

>merge|NZ_CP014485|6|1870661-1870762|CRISPRCasFinder
CCAGCCCGGCCGGCGTTTGAGGCCATCGGTGACCGCCACGGACGACCACCGGCACCGCAGGCCGAAGCCCGGCCACAACCAGCCCGGCCGGCGCTTGAGGCC

>NZ_CP014485|6|6|1870661-1870762|CRISPRCasFinder
CCAGCCCGGCCGGCGTTTGAGGCC	ATCGGTGACCGCCACGGACGACCACCGGCACCGCAGGCCGAAGCCCGGCCACAA
CCAGCCCGGCCGGCGCTTGAGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003951005.1|1877246_1877795_-|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl|CDD|367590
NZ_CP014485.1|WP_003951014.1|1866899_1868408_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl|CDD|235489
NZ_CP014485.1|WP_003951003.1|1879118_1880264_-|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl|CDD|234664
NZ_CP014485.1|WP_061404175.1|1858145_1858517_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003951017.1|1863326_1863638_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003951011.1|1870163_1870460_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl|CDD|178810
NZ_CP014485.1|WP_008410677.1|1868425_1868665_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404178.1|1878298_1879075_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP014485.1|WP_061404177.1|1864367_1866602_-|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NZ_CP014485.1|WP_037845343.1|1870824_1872993_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NZ_CP014485.1|WP_008410682.1|1863706_1864333_-|hypothetical-protein	unknown	unknown	gnl|CDD|377085
NZ_CP014485.1|WP_008410656.1|1881082_1882252_-|cysteine-desulfurase	unknown	unknown	gnl|CDD|224029
NZ_CP014485.1|WP_003951012.1|1868661_1870158_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl|CDD|234572
NZ_CP014485.1|WP_008410671.1|1875427_1876441_-|methionine-synthase	unknown	unknown	gnl|CDD|239426
NZ_CP014485.1|WP_008410664.1|1877880_1878243_+|DUF427-domain-containing-protein	unknown	unknown	gnl|CDD|377265
NZ_CP014485.1|WP_018470884.1|1873220_1875407_-|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NZ_CP014485.1|WP_061404176.1|1859675_1862813_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|226415
NZ_CP014485.1|WP_008410668.1|1876522_1877221_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|181298
NZ_CP014485.1|WP_003951002.1|1880325_1881060_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP014485.1|WP_059212636.1|1856297_1857419_+|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl|CDD|369642

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003951014.1|1866899_1868408_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl|CDD|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NZ_CP014485.1|WP_003951003.1|1879118_1880264_-|tRNA-2-thiouridine(34)-synthase-MnmA	gnl|CDD|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP014485.1|WP_061404177.1|1864367_1866602_-|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	1.54724e-92
NZ_CP014485.1|WP_003951011.1|1870163_1870460_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl|CDD|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	1.0549e-38
NZ_CP014485.1|WP_008410668.1|1876522_1877221_-|SDR-family-oxidoreductase	gnl|CDD|181298	PRK08219, PRK08219, SDR family oxidoreductase.	2.39264e-110
NZ_CP014485.1|WP_059212636.1|1856297_1857419_+|PQQ-dependent-sugar-dehydrogenase	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	1.25385e-86
NZ_CP014485.1|WP_037845343.1|1870824_1872993_-|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.91005e-104
NZ_CP014485.1|WP_008410682.1|1863706_1864333_-|hypothetical-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	0.00230578
NZ_CP014485.1|WP_008410656.1|1881082_1882252_-|cysteine-desulfurase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	2.62768e-160
NZ_CP014485.1|WP_003951012.1|1868661_1870158_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl|CDD|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NZ_CP014485.1|WP_008410671.1|1875427_1876441_-|methionine-synthase	gnl|CDD|239426	cd03310, CIMS_like, CIMS - Cobalamine-independent methonine synthase, or MetE. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme catalyses the last step in the production of methionine by transferring a methyl group from 5-methyltetrahydrofolate to L-homocysteine without using an intermediate methyl carrier. The active enzyme has a dual (beta-alpha)8-barrel structure, and this model covers both the N-and C-terminal barrel, and some single-barrel sequences, mostly from Archaea. It is assumed that the homologous N-terminal barrel has evolved from the C-terminus via gene duplication and has subsequently lost binding sites, and it seems as if the two barrels forming the active enzyme may sometimes reside on different polypeptides. The C-terminal domain incorporates the Zinc ion, which binds and activates homocysteine. Side chains from both barrels contribute to the binding of the folate substrate.	3.47784e-62
NZ_CP014485.1|WP_008410664.1|1877880_1878243_+|DUF427-domain-containing-protein	gnl|CDD|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	1.39122e-42
NZ_CP014485.1|WP_003951005.1|1877246_1877795_-|TIGR00730-family-Rossman-fold-protein	gnl|CDD|367590	pfam03641, Lysine_decarbox, Possible lysine decarboxylase. The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear.	1.53611e-38
NZ_CP014485.1|WP_018470884.1|1873220_1875407_-|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP014485.1|WP_061404178.1|1878298_1879075_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.13863e-11
NZ_CP014485.1|WP_003951002.1|1880325_1881060_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	5.8096e-32
NZ_CP014485.1|WP_061404176.1|1859675_1862813_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	1.43626e-37

Protein sequences

>NZ_CP014485.1|WP_003951011.1|1870163_1870460_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MPGITREEVAHLARLARLELKAEELEHFAGQLDDILGAVARVSEVAGQDVPPTSHPLPMTNVMRADEVRPSLTPEQALSGAPAQEQQRFKVPQILGED
>NZ_CP014485.1|WP_003951012.1|1868661_1870158_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MSDSIIKLTAAETAAKIASGELTAVEVTEAHLARIEAVDEKVHAFLHVDREGALAQARAVDAKRAAGEKLGPLAGVPLALKDIFTTEGIPTTVGSKILEGWIPPYDATVTKRLKDADVVILGKTNMDEFAMGSSTENSAYGPTGNPWDLTRIPGGSGGGSSAALAAFEAPLAIGTDTGGSIRQPAAVTGTVGVKPTYGGVSRYGMVAFSSSLDQGGPCARTVLDAALLHEAIAGHDPLDSTSIDAPVPPVVEAARNGSVAGMRVGVVKQFRGEGYQAGVVQRFDESVELLRKLGATVVELDCPSFDLALSAYYLIAPSECSSNLARFDAMRYGLRVGDDGTRSAEEVTAITREEGFGDEVKRRVILGTYALSSGYYDAYYGSAQKVRTLITRDFERAFEEVDVIVSPTTPTTAFPIGERADDPMAMYLADLCTIPTNLAGNAAMSLPCGLAPEDGLPVGLQIIAPAMKDDRLYKVGAAVEAAFVEQWGHPLLEEAPSL
>NZ_CP014485.1|WP_008410677.1|1868425_1868665_-|hypothetical-protein
MSALSKAKGFKKSKTGTYLSIGTTAFGALSVYKQMKAARHDHDTLSLVDAVATAAGIVTGVALLVRELKRLGDDDVLLG
>NZ_CP014485.1|WP_003951014.1|1866899_1868408_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MTVTDLVPYDDALAAYDPVMGLEVHVELGTKTKMFCGCSTELGADANSQTCPTCLGLPGSLPVVNAVGVESAVKIGLALHCEIAEWCRFARKNYFYPDMPKNFQTSQYDEPIAFDGYLDVQLEDGEVFRVEIERAHMEEDTGKSTHVGGATGRIHGASHSLLDYNRAGIPLIEIVTKPIEGAGERAPEVAKAYVAELRELIKALGVSEARMEMGQMRCDVNLSLRPKGRQEFGTRSETKNVNSLRSVERAARFEIQRHAAVLSSGGTIVQETRHFHEEDGSTTAGRIKDNAEDYRYFPEPDLVPVAPPREWVEELRSTLPELPRVRRNRLREEWGVSEHDMQSILNAGAIGPIVATIEAGADAAAARKWWMGELARNANETGRPLEGLPITPAQVARVAELVKGGDLNDKLARQVIEGVLAGEGDPDTVVEKRGLKVVSDEGALTTAVEEAIAGNPAIADKIRGGKVAAAGALVGAVMKATRGQADAARVKELILAQLGVEG
>NZ_CP014485.1|WP_061404177.1|1864367_1866602_-|MMPL-family-transporter
MAALARWCMHHRLLAVLLWLLVLGGAGTAAGLAGSAYTNDYAAGGTESGEATALIERGFPGLAGDSDTVVWHAPDSSVRAADVEQTMTHALDRIADLPGVASVAGPYAEAGTGPGGGISEDGRTAYATVTFAGQTSDISPAQAQAVVDAAHGADGDGLQVEVGGSAVALTEAPALHTAELIGVAVAAVVLFLAFGSLAASLLPIATALVSVGIGYAGIVLLGHVMTVADFAPMLGMLIGLGVGIDYALFIVTRHRTGLKQGLTVDAAAARAVATTGRAVVFAGATVCIALLGMLILRLEFLNGVAIAASLTVLLTVAASLTLLPALLAYIGPRALSRRERRRLAAEGPLPELPTGFAARWSRFVERHPKLLGVLATAVMAVLALPMLTLHLGTSDQGNNPASSTTRQAYDLLADEFGPGVNGPLTLVTEVGGAPDRLALDGLEQTLRQTEGVAGVTPVVFNDASDTALLTVVPTSSPQSEQTSALVDRLRADVLPRAEAGTGLDLKVGGMTAAYDDFAELIVGKLPLFIGVVIGLGFALLLLAFRSVGIPLKAALMNVMAVAGAFGVVVAIFQWGWGSELLGLGSSGPIEPFLPVIMVSVLFGLSMDYQVFLVSRMHEEWVATGDNTRAVRVGLAETGRVINSAAVIMISVFLAFVLSGDRLIAMFGIALAVAVALDAFVLRTLLVPALMHLLGRANWWLPGWLDRVLPRISIEGPPEQRAPHPAEVPVPRAPDEDPARSAALR
>NZ_CP014485.1|WP_008410682.1|1863706_1864333_-|hypothetical-protein
MDTKTADGKRPATGAEDEQQDTDGTTPGKTPGEEKDPAGKGAPAAAETDGVEAVHDAHDADDLDADDEAATEDTATAAPTGIAAGAAAIVSVVLGVVSLTGGWLGTIASARASLIGQLETSQGAGVADQVQAIYGDSWEAAALVGGAFAAVGLLVGIGVVLRVAYWPARTGPVWVRSAAWAGVAVGLVGLLLALSKYTGLLLGVPSAG
>NZ_CP014485.1|WP_003951017.1|1863326_1863638_+|hypothetical-protein
MSRLPAACLHTHLFRGARVLVDGLADPSGYARAPRPLELALRFSDDAPADAEVLVSPESGETVLAVGAYTTEAGTSLSSRTWLVGGVEARDAGVELTIGVRVG
>NZ_CP014485.1|WP_061404176.1|1859675_1862813_-|helix-turn-helix-transcriptional-regulator
MLTDVEHKSVSPVFVGRATELDTLRRALTEVRTGEPRALLIGGEAGVGKTRLLEEFTAEATGDGALVTLGACVESGTEGLPFAPFAAVLRTLRRLLPEEFAAGAAGQEGELARLLPDLGEAALARSGEEGTARLFDLTARLLEHLAAARPVVLVVEDLHWADASTRRLIAYLFRTLRTGRLLVLASYRADDIHRRHPLRPLLAELDRLRTVQRLEVPRFNRAEVAGQLAGILAAEPDDSTVDEVFARSEGNAFFVEELTVAARSGCHAGLTDSLRDLLLVRVEALPERSQHLVRLAAEAGPTTEYALLAAVARLPETDLLDALRAAVGAHILLPSEDGDGYRFRHALVREAVTDDLLPGERTRIGRQFAEALAADPTLVAPDAYATRLAGYWYRAHDAAKALPAVLRAAAEARHRHAYAEQFTLLERAMELWDGVPEEIRGALRSADHAEVYPHLTARRGPGTGEGPGAPLRYLHLMADAAVAGRLCGQRERAYKIAKKAVRMLGETRSTGESWDEPLFAAWFWVQRSRVAESVGRGDGWQELHTAQELVRGLPPSEMHAEVLSCVASWWMLHRPGPEAYAAAERAVQYARMVGADDDVELAARGTLAGLRIDSGDIDTGLAELREVLADALRRERPHQIGRCYVNLPSHLEGIGRSAEAAALIERGLKESDRYGLLFTATFLHANHAESLISLGRWDEALRSADAAAGLTGQAKPAGMAAHSRTVIALARGDLDTAVRQDAVARSRVGSHGAMPQHALPLATTRLSIAAAEGRVHDARAELRAAAETGFPPGTQRYAWPLLVAAATTESDARGLPGAEEGRADHIALVRHLAKNLVTFVPVCEAQAAWVRAELRRGEGQDTVEDWADVHQRFLPLERPWDLARVALRYAEALLADSGTRPGPGRTQAAELLRSARATARRLGARPLADSIDLLARRARLSLSTRPAATPRPDTPTDPAEALGLTRREREVLRLLVAGRTNRHIAEELFISPKTASVHVSHILAKLEVSSRGEAAAVAHRLRLVGSGAGGSGGDGGREKGVGVGA
>NZ_CP014485.1|WP_061404175.1|1858145_1858517_-|hypothetical-protein
MLTATRVDSEGKATVGAQYYGADSENGDRIDDPSEDALFMMISDLNDSDNTFVVVQPDEDDPVWFASVAVLDEGGYETVRRDTTRNEHEVTTATSVNDIARDLTIWMAARNFPGRPTSQVSES
>NZ_CP014485.1|WP_059212636.1|1856297_1857419_+|PQQ-dependent-sugar-dehydrogenase
MALLGAGCSSGPAEPESGPSSPGSASPSGSGSPSAASDAPPDKGSVEVVRTLATGLKSPWGLAPLPDGNLLVASRDEGEIVQVDGDSGKTSEAGQVPGVDAEGEGGLLGLALSPDFATDQLVYAYFTTASDNRIASMRYDAKKPAGERLSAPSTIFKGIPKGFTHNGGRIAFGPDKMLYVGTGETGDKGLAQDKESLGGKILRMTPEGEPAKGNPVQDSVVWSYGHRNVQGLAWDEDRRLWASEFGQDTWDELNHIEKDGNYGWPDVEGEGDGDGDFRNPVEQWRTADASPSGIAVAEGSVWMAGLRGERLWRIPLSGDKPSAKPQAFLEGEYGRLRTVVSAGGDKLWVVTNETDGRGSPEKDDDRILEVRVR
>NZ_CP014485.1|WP_037845343.1|1870824_1872993_-|EAL-domain-containing-protein
MEPTESAAPASWPRLRRTIAARTGPRRAPYGPGRAEGVTPLLPIAVIALAAVLLATGIGRAVATGHALFPAGAAGWALAVLTGIVVGHLVALGRDRWWGGTGSGAALTLAVLLLYGWVPAGLVSITVVVLVGVARRHRWRQGLLHGAVDILGIAAAALLLTLTGVTPSVETPWDPRSWTLATGTGVLFAAAGYLLMTRLLLWLVHTPNPGTLPTVTRTAVIRQSLVGVALLGIAPLICVVAVALPVLLPLFSIPLIALDSTLWIARARAEEQLRDPLTGLPNRQWLLERIWTALDEAEQAGTRSALLLIDLDRFRSVNDTLGHLAGDRLLLQIAERLRPALPRGAEAARLGGDEFAVLLPVADSTTAAQRVARRLVSELGSPLDLDGLTLVLEASAGVAVYPDHAQDAEGLLRRADVAMYQAKRDRTGVEVYESKRDSNTPDRLGLLGDLRRALDAGEVELHYQPKVRFDGHVAGLEALVRWVHPERGRVPPDEFIAIAESSGLMPHLTEYVLETALGQVARWRAQGLNVPVAVNVSPRDVHSPGFAGAVAARLARHGVPAGALQLEITEHVLLEDPQRAADTLAGLTGHGVKMSLDDFGTGYSSLVHLRRLPVSELKIDRSFVARLAVDTEDAEIVRCTVDLAHSLGLLVVAEGVEDDETWERLRDLGCDAVQGWLVAAAMPAGETTAWLRARGARGWRRPAEIAAEAAEAGRAVRSGPPQ
>NZ_CP014485.1|WP_018470884.1|1873220_1875407_-|NAD-dependent-DNA-ligase-LigA
MAGEQQNADVPADARERHKHLAEQVEEHRFRYYVNDQPVVSDAEFDRQLRALTELEEQYPPLRTPDSPTQKVAGQYETEFTSVQHRERMLSLDNAFDDEELAAWAERVAKEVGAPGYHFLCELKVDGLAVNLTYEHGRLTRAATRGDGRVGEDITPNVRTISDIPERLHGDDLPALVEIRGEVFFPMEEFEKLNARLVEAGEKPFANPRNAAAGSLRQKDPRVTATRPLHMVVHGIGAREGFTIDCLSHAYDLLRSWGLPTARHNKVVEGLDGVRAFITYYGDHRHSVEHEIDGVVVKLDEVPLQGRLGSTSRAPRWAIAWKYPPEEVNSRLIDIRVGVGRTGRVTPYAQVEPVTVAGSEVEFATLHNQDVVRAKGVLIGDTVVLRKAGDVIPEILGPVADLRDGTERPFTMPAECPECGTPLKPMKEGDIDLRCPNARSCPAQLRERIYYLAGRKCLDIENFGYVAATALTQPLEPSEPPLRDEGDLFDLTVDQLLPIRSYVLDPDSGLPKRDPKTGEEKIVTFFANKQGEAKKNTLAMLDHIEAAKQRPLARVLTGLSIRHVGPVAAQALAREFRSIERIEAATEEELAQTEGVGPTIAASLKSWFAEEWHREIVRKWREAGVRMEEESTGEDEGPRPLEGLTVVVTGTLEHHTRDNAKEALQNQGAKVTGSVSKKTSFVVVGDNPGSKYDKAMQAKVPVLDEAGFAVLLGQGPDAAREVALPLPE
>NZ_CP014485.1|WP_008410671.1|1875427_1876441_-|methionine-synthase
MSDTDDFPTLRATGIGSMPGGDAREAARTVTGTFAGGEGMPYLPELPARGPGADMTGRTAGLLADLHAQLEPSGWRIADRPGRDMRRAVSWLREDLDALEEYTQGYEGPLKLQVTGVWTLAAALQTRGGEAFLGDAGACRDLAASLAEGLRGHLAEVRRRVPGARLVLQLDEPSLTAVLTGTVRTASGYRTYRAVDRQVVESALREVAAVHDGPVLAHSCAPSVPFALLRRAGFAGASFDFSLLTEGDDEALGEGVEAGFRLLAGVVPGTDTALSDPAGSVMGVRTWWRRLGLNPGLLPEAVAITPSCGLAGASPGYARAALAHCVRAANSLADNPE
>NZ_CP014485.1|WP_008410668.1|1876522_1877221_-|SDR-family-oxidoreductase
MRAMATHVITGAGSGIGAAVARRLHERGDHLVLVARDAGRARELAAAHPGAETLVADLADPDRISWALSHQTLPDRIDSLLHIAGVVDLGTVGELTPKTWRHQIDVNLLAPAELTRHFLPQLRLTHGHVVFVNSGAGLNANGGWAAYAAAKHGLKALADALRQEEQEHGVRVTSVYPGRTASAMQQKIHQQEGKEYDPDRWISPESVATTLLTALDLPADAVINDVSIRPGG
>NZ_CP014485.1|WP_003951005.1|1877246_1877795_-|TIGR00730-family-Rossman-fold-protein
MNICVFLSAADLPERYTRPAREFAELLGKGGHTLVWGGSDKGLMKVVADGVEQSGGKLLGVSVEFLAASARPVPAESGEMIITADLAERKAQLLARADAVVIMVGGTGTLDEATEILELKKHGMHTKPVVLLNTAGFYDGLREQFQRMEDEGFLPLPLTELVLFAEEPVGALAHLEESAGVQ
>NZ_CP014485.1|WP_008410664.1|1877880_1878243_+|DUF427-domain-containing-protein
MTQGHGDDTARGHRITVEQAPVHVRVVRDGQVVAESRRPLLLRETGLPVRYYLPPEDVRTDLLTPSETHTVCPFKGTASYWSLPGEPDLVWAYPEPIEAVAEIRDHFCFYETEVVAEPAG
>NZ_CP014485.1|WP_061404178.1|1878298_1879075_+|alpha/beta-hydrolase
MDTVVSRDGTPIAYGTRGSGPALVLVGGAMTTGEHAAPLAGLLADSFTVVTYDRRGRGRSGDTRPYAVGREVEDLAEVIRAVGGPAALYGVSSGAALALHAASAGTAVSRVALYEPPFTVGEADPSRREAYRSRLVALLAADDRGGAVELFMTHIGLPPEMIAGARRSPAWPGLEAVAPTLAYDDELLGDGAPPLDRLALVPVPALVMAGSASPPAMTEAARTVAEALPEGTYRELGGQTHDVAPEAVAAALREFLLP
>NZ_CP014485.1|WP_003951003.1|1879118_1880264_-|tRNA-2-thiouridine(34)-synthase-MnmA
MTETSPRTENPPRPLRVLAAMSGGVDSAVAAARAAEAGHDVTGVHLALSANPQSFRTGARGCCTIEDSRDARRAADVIGIPFYVWDLAERFREDVVEDFVAEYEAGRTPNPCLRCNEKIKFAALLDKALALGFDAVCTGHYATVVTREDGSRELHRASDMAKDQSYVLGVLDERQLAHALFPLGDTLTTKDEIRAEAERRGLAVAKKPDSHDICFIADGDTRGFLAGRLGTAEGDILDEAGQKVGTHEGAYGYTIGQRKGLRIGTPAADGKPRYVLDISPVDNTVTVGPAAALDVTGLTAIRPRWCGTPPEGSGRYTAQLRAHGEETPVTAEVREGELTVTFDEPVRGVAPGQAVVLYDGSRVVGSATIAATRRAGAVPAA
>NZ_CP014485.1|WP_003951002.1|1880325_1881060_+|N-acetylmuramoyl-L-alanine-amidase
MGNGNHSAGAGRGADGGQGARRRTVRRRSVLIGAGVAAATGGVLAREELGRLWYQVPGVSKPRVEGAVDYAKAEWVAASDANWRRADRPDDFTVDRVIIHVVQGSYAVALKVFQDPAHRAATHYVVGKDGRVAQLIRELDVAYQAGNREYNERAVGIEHEGFVDRPQDFTGAMYESSARLTADICLRHGIPVDRTHVIGHVEVPGTDHTDPGPHWDWDRYLRLVRAAKKQLEREREQDERRERA
>NZ_CP014485.1|WP_008410656.1|1881082_1882252_-|cysteine-desulfurase
MAYLDHAATTPMLPEAVEAMSAQLTRTGNASSLHAAGRRARRTAEEARETLAEALGARPSEVVITAGGTEADNLAVKGLYWARRAADPRRTRVLASPVEHHAVLDAVHWLGEHEGATVEYLPVDTLGRVHPEALREALARNPHDVALATVMWANNEIGTVQPVTELAAVAAEYEIPLHADAVQAFGQLPLEFGASGLAAATVSGHKIGGPYGIGALLLGRQYTPVPVLHGGGQERHVRSGTLDVPAIASFAVAGQLAAERRPRFAEEIGALRDELVAAVHDAVPDAILGGDPDPAGRLPANAHFTFPGCEGDSLLLLLDAQGIECSTGSACTAGVAQPSHVLLATGTPPDLARGTLRFSLGHTSTRADVEAVAKAIGPAVERARNAGLS

Crispr_ID: NZ_CP014485_7

• CRISPR_ID: NZ_CP014485_7
• CRISPR_location: 2031546-2031687
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014485_7

Consensus_repeat	Method
AGCCTGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP014485_7

>7.1|2031569|39|NZ_CP014485|CRISPRCasFinder
TCGGTGACCGCAACTGGTCGACGCATCCCGACCAATCCA
>7.2|2031631|34|NZ_CP014485|CRISPRCasFinder
AACTCAGCCCGGCCGGCGCCTGAGGCCACAACTC

CRISPR arrays and Neighbor proteins around NZ_CP014485_7

CRISPR arrays

The CRISPR arrays of NZ_CP014485_7

>merge|NZ_CP014485|7|2031546-2031687|CRISPRCasFinder
AGCCCGGCCGGCACTTGAGGCCATCGGTGACCGCAACTGGTCGACGCATCCCGACCAATCCAAGCCTGGCCGGCGCTTGAGGCCAAACTCAGCCCGGCCGGCGCCTGAGGCCACAACTCAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP014485|7|7|2031546-2031687|CRISPRCasFinder
AGCCCGGCCGGCACTTGAGGCCA	TCGGTGACCGCAACTGGTCGACGCATCCCGACCAATCCA
AGCCTGGCCGGCGCTTGAGGCCA	AACTCAGCCCGGCCGGCGCCTGAGGCCACAACTC
AGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003950870.1|2029928_2031005_-|peptide-chain-release-factor-1	unknown	unknown	gnl|CDD|234801
NZ_CP014485.1|WP_003950867.1|2031149_2031371_-|50S-ribosomal-protein-L31	unknown	unknown	gnl|CDD|234576
NZ_CP014485.1|WP_061404212.1|2040981_2041956_-|hypothetical-protein	unknown	unknown	gnl|CDD|223097
NZ_CP014485.1|WP_061404211.1|2033343_2035404_-|transcription-termination-factor-Rho	unknown	unknown	gnl|CDD|237171
NZ_CP014485.1|WP_061404209.1|2025858_2027211_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl|CDD|133463
NZ_CP014485.1|WP_078485248.1|2038163_2039456_-|homoserine-dehydrogenase	unknown	unknown	gnl|CDD|235783
NZ_CP014485.1|WP_003950878.1|2023716_2023953_-|ATP-synthase-F0-subunit-C	unknown	unknown	gnl|CDD|169138
NZ_CP014485.1|WP_003950861.1|2039570_2040962_-|diaminopimelate-decarboxylase	unknown	unknown	gnl|CDD|273415
NZ_CP014485.1|WP_049977114.1|2043088_2044240_+|restriction-endonuclease	unknown	unknown	gnl|CDD|375528
NZ_CP014485.1|WP_061404210.1|2027490_2028165_-|protein-tyrosine-phosphatase	unknown	unknown	gnl|CDD|319972
NZ_CP014485.1|WP_026235361.1|2024036_2024864_-|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl|CDD|235617
NZ_CP014485.1|WP_010642250.1|2031751_2032897_-|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP014485.1|WP_003950864.1|2035787_2036705_-|homoserine-kinase	unknown	unknown	gnl|CDD|234920
NZ_CP014485.1|WP_003950875.1|2025117_2025546_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008409324.1|2029042_2029888_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl|CDD|236467
NZ_CP014485.1|WP_003950879.1|2023125_2023671_-|F0F1-ATP-synthase-subunit-B	unknown	unknown	gnl|CDD|180240
NZ_CP014485.1|WP_003950872.1|2028161_2028809_-|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl|CDD|223088
NZ_CP014485.1|WP_061404213.1|2044379_2045447_+|glycoside-hydrolase-family-43-protein	unknown	unknown	gnl|CDD|350141
NZ_CP014485.1|WP_010642262.1|2042108_2042564_-|response-regulator	unknown	unknown	gnl|CDD|381093
NZ_CP014485.1|WP_003950863.1|2037098_2038157_-|threonine-synthase	unknown	unknown	gnl|CDD|236013

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003950870.1|2029928_2031005_-|peptide-chain-release-factor-1	gnl|CDD|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NZ_CP014485.1|WP_003950867.1|2031149_2031371_-|50S-ribosomal-protein-L31	gnl|CDD|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	2.79574e-38
NZ_CP014485.1|WP_061404212.1|2040981_2041956_-|hypothetical-protein	gnl|CDD|223097	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	2.29159e-21
NZ_CP014485.1|WP_061404211.1|2033343_2035404_-|transcription-termination-factor-Rho	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0
NZ_CP014485.1|WP_061404209.1|2025858_2027211_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl|CDD|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	1.99392e-89
NZ_CP014485.1|WP_078485248.1|2038163_2039456_-|homoserine-dehydrogenase	gnl|CDD|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NZ_CP014485.1|WP_003950878.1|2023716_2023953_-|ATP-synthase-F0-subunit-C	gnl|CDD|169138	PRK07874, PRK07874, ATP synthase F0 subunit C.	2.66672e-18
NZ_CP014485.1|WP_003950861.1|2039570_2040962_-|diaminopimelate-decarboxylase	gnl|CDD|273415	TIGR01048, Diaminopimelate_decarboxylase, diaminopimelate decarboxylase. This family consists of diaminopimelate decarboxylase, an enzyme which catalyzes the conversion of diaminopimelic acid into lysine during the last step of lysine biosynthesis. [Amino acid biosynthesis, Aspartate family].	3.11225e-166
NZ_CP014485.1|WP_049977114.1|2043088_2044240_+|restriction-endonuclease	gnl|CDD|375528	pfam18062, RE_AspBHI_N, Restriction endonuclease AspBHI N-terminal. This is the N-terminal domain found in modification-dependent restriction endonuclease proteins such as AspBHI, which can be found in Azoarcus sp. AspBHI is a homo-tetrameric protein that recognizes 5-methylcytosine in the double-strand DNA sequence context of (C/T) (C/G) (5mC) nucleotide (C/G) and cleaves the two strands at a fixed distance (N12/N16) 3 to the modified cytosine. The N-terminal domain is responsible for DNA-recognition and resembles an SRA-like 5-methylcytosine binding domain in structure and function.	9.0541e-38
NZ_CP014485.1|WP_061404210.1|2027490_2028165_-|protein-tyrosine-phosphatase	gnl|CDD|319972	cd16344, LMWPAP, low molecular weight protein arginine phosphatase. Low molecular weight protein arginine phosphatases are part of the low molecular weight phosphatase (LMWP) family. They share a highly conserved active site motif (V/I)CXGNTCRS. It has been shown that the conserved threonine, which in many LMWPTPs is an isoleucine, confers specificity to phosphoarginine over phosphotyrosine.	1.42825e-24
NZ_CP014485.1|WP_026235361.1|2024036_2024864_-|F0F1-ATP-synthase-subunit-A	gnl|CDD|235617	PRK05815, PRK05815, F0F1 ATP synthase subunit A; Validated.	1.41133e-57
NZ_CP014485.1|WP_010642250.1|2031751_2032897_-|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	1.60988e-61
NZ_CP014485.1|WP_003950864.1|2035787_2036705_-|homoserine-kinase	gnl|CDD|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	7.46567e-104
NZ_CP014485.1|WP_003950863.1|2037098_2038157_-|threonine-synthase	gnl|CDD|236013	PRK07409, PRK07409, threonine synthase; Validated.	0
NZ_CP014485.1|WP_008409324.1|2029042_2029888_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl|CDD|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	4.68294e-107
NZ_CP014485.1|WP_003950879.1|2023125_2023671_-|F0F1-ATP-synthase-subunit-B	gnl|CDD|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	2.60829e-40
NZ_CP014485.1|WP_003950872.1|2028161_2028809_-|threonylcarbamoyl-AMP-synthase	gnl|CDD|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	1.6884e-65
NZ_CP014485.1|WP_061404213.1|2044379_2045447_+|glycoside-hydrolase-family-43-protein	gnl|CDD|350141	cd18820, GH43_LbAraf43-like, Glycosyl hydrolase family 43 proteins similar to Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43 and Geobacillus thermoleovorans GbtXyl43B. This uncharacterized glycosyl hydrolase family 43 (GH43) subgroup belongs to a subgroup which includes enzymes with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55) and possibly bifunctional xylosidase/arabinofuranosidase activities, similar to Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43 and Geobacillus thermoleovorans IT-08 beta-xylosidase / exo-xylanase (GbtXyl43B). It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	9.83143e-94
NZ_CP014485.1|WP_010642262.1|2042108_2042564_-|response-regulator	gnl|CDD|381093	cd17538, REC_D1_PleD-like, first (D1) phosphoacceptor receiver (REC) domain of response regulator PleD and similar domains. PleD contains a REC domain (D1) with the phosphorylatable aspartate, a REC-like adaptor domain (D2), and the enzymatic diguanylate cyclase (DGC) domain, also called the GGDEF domain according to a conserved sequence motif, as its output domain. The GGDEF-containing PleD response regulators are global regulators of cell metabolism in some important human pathogens. This model describes D1 of PleD and similar domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	6.94425e-30

Protein sequences

>NZ_CP014485.1|WP_003950867.1|2031149_2031371_-|50S-ribosomal-protein-L31
MKRDIHPEYVETQVSCTCGAAFTTRSTIASGTVRADVCSECHPFYTGKQKILDTGGRVARFEARFGKAAGTKK
>NZ_CP014485.1|WP_003950870.1|2029928_2031005_-|peptide-chain-release-factor-1
MFEAVEELIGEHADIEKRLADPAVHADQAGARKLNKRYAELTPIVGTYRSWKQTGEDIETARELAADDPDFAAEVKELEAAREELTEKLRLLLVPRDPSDDKDVILEIKAGAGGDESALFAGDLLRMYLRYAERVGWKTELIDSTESELGGYKDVQVAVKTKGGQGATEPGQGVWARLKYEGGVHRVQRVPATESQGRIHTSAAGVLVTPEAEEIDVEINQNDLRIDVYRSSGPGGQSVNTTDSAVRITHLPTGVVASCQNEKSQLQNKEQALRILRSRLLAAAQEEAEREAADARRSQVRTVDRSEKIRTYNYPENRISDHRVGFKAYNLDQVLDGELDAVIQACVDADSAAKLAAA
>NZ_CP014485.1|WP_008409324.1|2029042_2029888_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MNLLLAEVAQATQRLADAGVPSPRNDAEELAAYVHQVKRGALHTVKDSDFDARYWEAIARREAREPLQHITGLAYFRYLELQVGPGVFVPRPETESVVGWAIDAVRAMDVVEPLVVDLCSGSGAIALALAQEVPRSTVHAVELSEDALVWTRKNVEGSRVHLHQGDAFGALPELDGQVDLVISNPPYIPLTEWEYVAPEARDHDPQMALFSGEDGLDTIRGIERTAHRLLRPGGIVVVEHADTQGGQVPWIFTEEKGWADAADHPDLNNRPRFATARKALP
>NZ_CP014485.1|WP_003950872.1|2028161_2028809_-|threonylcarbamoyl-AMP-synthase
MARRYDTNDATDRVTGLREAASAVRRGELVVLPTDTVYGVGADAFSPEAVGDLLTAKGRGRNMPSPVLIGSPNTLHGLVTDFSETAWDLVDAFWPGALTLVARHQPSLQWNLGDTRGTVAVRMPLHPVAIELLTETGPMAVSSANLTGHPSPETCEAARNMLGDAISVYLDGGPTPGIVPSSIVDVTGSVPVLLRAGAIDADELRKVVPDLEVAS
>NZ_CP014485.1|WP_061404210.1|2027490_2028165_-|protein-tyrosine-phosphatase
MIVPEGRGIAAQPPGGTFRILHVSTGNVCRSPITERLTRHALADRLGLTGLAGGTESGVGGVIVESAGTWGHEGAPMEANAEAVLASLGADAAGFRGRELLDEHVIRADLVLTATRDHRAQVISMGHSAGLRTFTLKEFTRLVRAIDPATLPDPLEGGVVGRARALVQAAAALRGWLLAPSVEADEVLDPYGAPMPFFQAVGEEIQVALEPVLTALTGVGQPTG
>NZ_CP014485.1|WP_061404209.1|2025858_2027211_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MREYLLTLCITAAVTYLLTGPVRKFAIVAGAMPEIRARDVHREPTPRLGGIAMFFGLCAGLLVADHLTNLGEVFDSNEPRALLSGAALIWLIGVLDDKFEIDALVKLGGQLIAAGVMVMQGLTMLWLPVPGVGQVLLTSWQGNLLTIALVLITINAVNFVDGLDGLAAGMVCIAATAFFMHAYRIWYGYGLEAAAPAALFAALLMGMCLGFLPHNMHPARIFMGDSGSMLIGLVLAAGAISITGQVDPDAMGLFAGSEKAAVHQTVPVYMPLLLPLTIIAVPAADLVLAVVRRTWRGQSPFAADRGHLHHRLLEIGHSHSRAVLIMYFWSALIAFGALAYSVNEASMWVALGVAALSAVGLVLLLLPRFTPRAPRWAEAFVPPRYRRRVSAGPRQEGVVTEGEAGAEGTEPSARVTVGVSGANGATAVGERSRFGGRGGGEREKATSTRS
>NZ_CP014485.1|WP_003950875.1|2025117_2025546_-|hypothetical-protein
MLSNDARILRGAAIPSLGAGLIGTLIGGITVGSQGAIGGAVGTALTLAFFGAGLKAMSVIGRRWSELFMAAGLLVYTTQILVMAILLAVFRDATFMDGRVFGLTMLACVLVWIAGQAWMHTRVKTLYVEPESEDEPVGPERR
>NZ_CP014485.1|WP_026235361.1|2024036_2024864_-|F0F1-ATP-synthase-subunit-A
MSKELAVSSDQLLAFETDCHLFKDCGFPAPSVWSFLFDPIFSVGPVDFNKPMLLALIGTVVILAFFWAAFSKPKLVPGKFQMVAEILYDFVRNGIARETIGKKGEPFVPFLVSLFFFVWILNLWALIPLAQFPVNSVIAFPVGLALMVWIVYMTVTFKTNGFVGGIRNLCVPSGLPKPIYVILTPIEFVSNIFVRPFTLAVRLFANMFAGHILILIFTIATWYMLGTLLGTVYATASFALTLVLTVFEMFIQALQAYVFTVLTATYLSQALEEAH
>NZ_CP014485.1|WP_003950878.1|2023716_2023953_-|ATP-synthase-F0-subunit-C
MSAAFETLAAVTGNIGTIGYGLAAIGPGVGVGIIFGNGVQAMARQPEAAGLIRQNMLLGFAVVEALALIGFVVPFILS
>NZ_CP014485.1|WP_003950879.1|2023125_2023671_-|F0F1-ATP-synthase-subunit-B
MMYLAAEEPQNPLLPVWPEVVIGLLCFAIIFFVFAKKLLPSINKVLDERHDKIVGGIEEAEAAQVEAQSVLEQYKAQLAEARHEAARLRSEAQEQGATLIAEMRAEGQRQREEIIAAGHAQIEADRKAAAQSLRQDVGQLATELAGKIVGESLEEHARQSRTIDRFLDGLDDAATKAEATR
>NZ_CP014485.1|WP_010642250.1|2031751_2032897_-|LCP-family-protein
MAEQTSQDGDTPENGEEARRARRIRPTGQRRRPRSRRRKILLAAAWTAAGGILVGGAGLGFAYVKLNGNLEGVDINAALGSDRPEEVDDGSLDLLVLGSDSRSGDNGKYGRDEGAARSDTAMIVHLHEGRKKATVVSIPRDTLVTRPDCAAEDGSTVSGGQRQMFNTAYEAGGPACAVKTVEQMSGIRMDHYLEVDFSGFQEIIDRLGGVEVTTGKAIDDDKSGLHLDKGTHTLDGEQSLGLVRTRHGVGDGSDLGRIQLQQTFLTALMHRVQDMGLLSSPKKLYGVADAATKSLTTDAELDSVPALLDFAQGLKGLKPEGMEMLTLPVEYDPADANRVLPQEKAGAQVWKALRADKAVPASATEGSAGDKGDVDDVVSAG
>NZ_CP014485.1|WP_061404211.1|2033343_2035404_-|transcription-termination-factor-Rho
MSDTTDLMGVTADSTVDSAAAPATDASAAPAAGSRRRRGTGLEGMVLAELQQVASGLGIRGTARMRKSQLIEVIKEAQAGGGAAAPAKSEPEAAKPKRRATSKARTGEAEAAAEPAQKPAKAAEKKQAKVAEQAEPEAQQDSQQQIDIPGQGAGDEQPAGERRRRRATAEAGSPEQAEAKQERAAKQQDQKGEGRGDDGSGQQQDGGEGRRDRQNRRDRDRGDRERGDRSERGERGGRDRDRRKGDDGGQGGQGGGNRQQQGGGQNRDRHDDFDDDGGGRRGRRGRYRDRRGRRGRDEVGEPQVNEDDVLIPVAGILDILDNYAFIRTSGYLPGPNDVYVSLAQVRKNGLRKGDHVTGAVRQPKDGERREKFNALVRLDSVNGMAPESGRGRPEFNKLTPLYPQDRLRLETDPGVLTTRIIDLVSPIGKGQRGLIVAPPKTGKTMIMQAVANAITHNNPECHLMVVLVDERPEEVTDMQRSVKGEVISSTFDRPAEDHTTVAELAIERAKRLVELGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTALYPPKRFFGAARNIEDGGSLTILATALVDTGSRMDEVIFEEFKGTGNMELKLDRKLADKRIFPAVDVDASGTRKEEILLSGEELGIVWKLRRVLHALDQQQAIELLLDKMRKTQSNAEFLLQIQKTTPTAGGND
>NZ_CP014485.1|WP_003950864.1|2035787_2036705_-|homoserine-kinase
MAGPAFRAAAVRVRVPATSANLGPGYDAFGLSLGLYDDVVVRVADSGLHIDIAGEGSETLPRDEDHLLVRAMRTAFDLLGGQPRGLEIVCANRIPHGRGLGSSSAAICAGIVAARAVTIGAEAKLDDAALLELATEIEGHPDNVAACLLGGFTLAWTESGAARAIRMEPDSSVVPVVFVPGKPVLTETARGLLPRTVPHVDAAANAGRAALLVEALTRRPELLLAATEDRLHQEYRAPAMPDSTALVERLRADGVPAVISGAGPTVLAFATDGAAEKVARLAGDGWAANRLALDLSGAGVLPLAP
>NZ_CP014485.1|WP_003950863.1|2037098_2038157_-|threonine-synthase
MTHQWRGIIEEYRDRLPVSDTTPVVTLREGGTPLVPAQVLSERTGCEVHLKVEGANPTGSFKDRGMTMAISKAKEEGAQAVICASTGNTSASAAAYAVRAGMVSAVLVPQGKIALGKMGQALVHGAKILQVDGNFDDCLTLARALSEQYPVALVNSVNPVRIEGQKTAAFEIVDFLGDAPDIHVLPVGNAGNITAYWRGYREYAADAVSTRTPRMWGFQAAGSAPLVRGEVVKDPATIATAIRIGNPASWDYAIQARDESGGFIDEVTDRQILSAYRLLASQEGVFVEPASAASVAGLLKAAEQGKVDPGQRIVCTVTGNGLKDPDWAVAGAPQPLTVPVDATAAAERLGLA
>NZ_CP014485.1|WP_078485248.1|2038163_2039456_-|homoserine-dehydrogenase
MMRTRPLKVALLGCGVVGSEVARIMTTHAADLAARIGAPVELAGVAVRRPDRVREGIDPSLVTTDATALVKRGDIDVVVEVIGGIEPARTLITTAFEHGASVVSANKALLAQDGAALHAAAEANGRDLYYEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTTNFILDKMDSTGAGYQEALDEATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVYREGMTEVTAADIASARRMGCTIKLLAICERAADGESVTARVHPAMIPLTHPLASVREAYNAVFVESEAAGQLMFYGPGAGGSPTASAVLGDLVAVCRNRLAASRGPGESAYTRLPVSPMGKVVTRYHISLDVADKPGVLAQVATVFAEHGVSIDTVRQTGKDGEASLVVVTHRAHDAALSGTVEALRNLDTVRGVASIMRVEGE
>NZ_CP014485.1|WP_003950861.1|2039570_2040962_-|diaminopimelate-decarboxylase
MSRSAHPAGPRHADVLPEGHYSAPAEDLNALDPKVWARTVRRDEDGVLTVGGLPVTRLAEEFGTPAFFLDETDFRARCRAWRDAFGADADVFYAGKAFLSRAVVRWLHEEGLNLDVCSGGELATALDAGMPAARIAFHGNNKTTAEIRRAVEAGVGRIVLDSFEEIVRVAHVADELGVRQPVQIRVTVGVEAHTHEFIATAHEDQKFGLALAGGQAAEAVRRALKLDGLELIGIHSHIGSQIFDMAGFEVSARRVVQLLAEVRDEHGVELPEIDLGGGLGIAYTSDDDPREPHEIAKALGEIVTRECESAGLATPRISVEPGRAIVGPTAFTLYEVGTVKPLEGLRTYVSVDGGMSDNIRTALYDAEYTVTLASRTSDAEPMLVRVVGKHCESGDIVVRDAFLPADLAPGDLLAVPATGAYCRSMASNYNHALRPPVVAVDEGAARVVVRRETEEDLLRLDVG
>NZ_CP014485.1|WP_061404212.1|2040981_2041956_-|hypothetical-protein
MTPADLSRAVLSAVRSAVDGGELAVAVPERVVVERPGPGGAGEWASNVALRLAREAGRPPREVAEVLRNRLVAAPGVAGVEVTGPGFLNVTLAGDSVGALVDRIAAEGEAYGSGDALREAAPVAVPDRSELRARIVAEAAGRLVRAQGGSVRGGGAAPVPARPGLDSEAVLGDDGLRWALLHPAPHDLPHGAEVLEQRARNPLFRVRYAHARSRGLVAGGDALGIVPGAGPVSGEAARVLTGLLGEQPAVLVAAARKGAPDRLARQLVTLADAFFDFHDSCDVLPRGGEKPGAAHRARLALAEAAGTVLAGGLSLLGISAPDHL
>NZ_CP014485.1|WP_010642262.1|2042108_2042564_-|response-regulator
MCGRVLVVDDNKVIRQLIRVNLELEGFEVVTAVDGAECLDMVHRVRPDVVTLDVVMPRLDGVRTAARLRADERTRDVPIVMVSGCEGGGAAQGAADAEVDAFLAKPFDPQELVRVVGQLRERRRAPEGQDPGDRDDEDEGEFPEGAGRAQG
>NZ_CP014485.1|WP_049977114.1|2043088_2044240_+|restriction-endonuclease
MAKVTVNGRPRRPAILIRSSPWKAGSEQTPWHDVFDMDNGHVRYFGDHKAGTTKPTGTTTGNAALLEAFEEHQAPTPEARAGAAPLLLFRAVSRDGRVKGFVEFCGVGVIERAERIVQWAGHEHTTFTNYVYDIALLDLTAENDQVDWDWITARRGTAVSDQDALAKAPRGWRDWTKRGHSALPRIRRRVAKARITKVRDQRPAPGSPRHKDLQFVYRQFDERKHDFEAVASAVAARVLRGTGHNYREGWITRRSGDGGADFVGRIDLGTGLAGTSLVVLGQAKCVRPESLVSAEQIARVVARLRRGWLGVYVTTGAFSEQAQLEMVEDQYPIVLVNGTDLARELRVMARDDHGDDLAACLNHILYVQGVPVAHRRPEEILLD
>NZ_CP014485.1|WP_061404213.1|2044379_2045447_+|glycoside-hydrolase-family-43-protein
MTSSRRIRALVGALLSCALAAGLGLATASPAAAGQVMRAADPSVIRVGSTYVSVQSAGGGLVVRQASSTEGLAGAEGRQVWADSAGLGEVWAPEIVRDGGRYHIYFAAGRGAAHRMYVISSDQADQGYGGATKLALPEDKWAIDGALFTFEGQRWFVWSGWEGDTDVEQNLYLARMNSPTEPTGPRYVISQPRESWERVVGNPFINEGPEPIMDPNGQLHIAYSANGSWSDQYCVADLRLRKGGDPTYVWDWYKSNGCLFGSHRETMMQGWDPTLYVDGPGHHSFVLLDGDIATSPPAGPRFPSMFHAVAKGTPYAWENRHWYTGTFTWWGETTYRRSGVPGAETDTGWSLKYFE

Crispr_ID: NZ_CP014485_8

• CRISPR_ID: NZ_CP014485_8
• CRISPR_location: 2042040-2042124
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_8

Consensus_repeat	Method
GGCCCGGGTCTCAGCCCTGGGCGCGT	CRISPRCasFinder

spacers of NZ_CP014485_8

>8.1|2042066|33|NZ_CP014485|CRISPRCasFinder
GGGGGCGAGGCGGGAGGAGGCTCACTCAGGTAT

CRISPR arrays and Neighbor proteins around NZ_CP014485_8

CRISPR arrays

The CRISPR arrays of NZ_CP014485_8

>merge|NZ_CP014485|8|2042040-2042124|CRISPRCasFinder
GGCCCGGGTCTCAGCCCTGGGCGCGTGGGGGCGAGGCGGGAGGAGGCTCACTCAGGTATGGCCCGGGTCTCAGCCCTGGGCGCGT

>NZ_CP014485|8|8|2042040-2042124|CRISPRCasFinder
GGCCCGGGTCTCAGCCCTGGGCGCGT	GGGGGCGAGGCGGGAGGAGGCTCACTCAGGTAT
GGCCCGGGTCTCAGCCCTGGGCGCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003950870.1|2029928_2031005_-|peptide-chain-release-factor-1	unknown	unknown	gnl|CDD|234801
NZ_CP014485.1|WP_078485248.1|2038163_2039456_-|homoserine-dehydrogenase	unknown	unknown	gnl|CDD|235783
NZ_CP014485.1|WP_061404212.1|2040981_2041956_-|hypothetical-protein	unknown	unknown	gnl|CDD|223097
NZ_CP014485.1|WP_061404211.1|2033343_2035404_-|transcription-termination-factor-Rho	unknown	unknown	gnl|CDD|237171
NZ_CP014485.1|WP_061404215.1|2049931_2050819_+|cytochrome-c-biogenesis-protein-CcdA	unknown	unknown	gnl|CDD|223856
NZ_CP014485.1|WP_061404214.1|2045470_2046886_-|NAD-dependent-succinate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143418
NZ_CP014485.1|WP_003950867.1|2031149_2031371_-|50S-ribosomal-protein-L31	unknown	unknown	gnl|CDD|234576
NZ_CP014485.1|WP_003950861.1|2039570_2040962_-|diaminopimelate-decarboxylase	unknown	unknown	gnl|CDD|273415
NZ_CP014485.1|WP_049977114.1|2043088_2044240_+|restriction-endonuclease	unknown	unknown	gnl|CDD|375528
NZ_CP014485.1|WP_010642250.1|2031751_2032897_-|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP014485.1|WP_003950864.1|2035787_2036705_-|homoserine-kinase	unknown	unknown	gnl|CDD|234920
NZ_CP014485.1|WP_003950863.1|2037098_2038157_-|threonine-synthase	unknown	unknown	gnl|CDD|236013
NZ_CP014485.1|WP_008409324.1|2029042_2029888_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl|CDD|236467
NZ_CP014485.1|WP_061404216.1|2051703_2052840_-|Ku-protein	unknown	unknown	gnl|CDD|238408
NZ_CP014485.1|WP_078944235.1|2047718_2048615_-|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|274373
NZ_CP014485.1|WP_015507099.1|2050888_2051683_+|class-I-SAM-dependent-methyltransferase-family-protein	unknown	unknown	gnl|CDD|371922
NZ_CP014485.1|WP_033238097.1|2052913_2053819_+|ATP-dependent-DNA-ligase	unknown	unknown	gnl|CDD|240133
NZ_CP014485.1|WP_061404213.1|2044379_2045447_+|glycoside-hydrolase-family-43-protein	unknown	unknown	gnl|CDD|350141
NZ_CP014485.1|WP_015507096.1|2047157_2047643_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_CP014485.1|WP_015507097.1|2049131_2049935_+|DsbA-family-protein	unknown	unknown	gnl|CDD|224565

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003950870.1|2029928_2031005_-|peptide-chain-release-factor-1	gnl|CDD|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NZ_CP014485.1|WP_078485248.1|2038163_2039456_-|homoserine-dehydrogenase	gnl|CDD|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NZ_CP014485.1|WP_061404212.1|2040981_2041956_-|hypothetical-protein	gnl|CDD|223097	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	2.29159e-21
NZ_CP014485.1|WP_061404211.1|2033343_2035404_-|transcription-termination-factor-Rho	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0
NZ_CP014485.1|WP_061404215.1|2049931_2050819_+|cytochrome-c-biogenesis-protein-CcdA	gnl|CDD|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	3.95707e-22
NZ_CP014485.1|WP_061404214.1|2045470_2046886_-|NAD-dependent-succinate-semialdehyde-dehydrogenase	gnl|CDD|143418	cd07100, ALDH_SSADH1_GabD1, Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like. Succinate-semialdehyde dehydrogenase 1 (SSADH1, GabD1, EC=1.2.1.16) catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde (SSA) to succinate. SSADH activity in Mycobacterium tuberculosis (Mtb) is encoded by both gabD1 (Rv0234c) and gabD2 (Rv1731). The Mtb GabD1 SSADH1 reportedly is an enzyme of the gamma-aminobutyrate shunt, which forms a functional link between two TCA half-cycles by converting alpha-ketoglutarate to succinate.	0
NZ_CP014485.1|WP_003950867.1|2031149_2031371_-|50S-ribosomal-protein-L31	gnl|CDD|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	2.79574e-38
NZ_CP014485.1|WP_003950861.1|2039570_2040962_-|diaminopimelate-decarboxylase	gnl|CDD|273415	TIGR01048, Diaminopimelate_decarboxylase, diaminopimelate decarboxylase. This family consists of diaminopimelate decarboxylase, an enzyme which catalyzes the conversion of diaminopimelic acid into lysine during the last step of lysine biosynthesis. [Amino acid biosynthesis, Aspartate family].	3.11225e-166
NZ_CP014485.1|WP_049977114.1|2043088_2044240_+|restriction-endonuclease	gnl|CDD|375528	pfam18062, RE_AspBHI_N, Restriction endonuclease AspBHI N-terminal. This is the N-terminal domain found in modification-dependent restriction endonuclease proteins such as AspBHI, which can be found in Azoarcus sp. AspBHI is a homo-tetrameric protein that recognizes 5-methylcytosine in the double-strand DNA sequence context of (C/T) (C/G) (5mC) nucleotide (C/G) and cleaves the two strands at a fixed distance (N12/N16) 3 to the modified cytosine. The N-terminal domain is responsible for DNA-recognition and resembles an SRA-like 5-methylcytosine binding domain in structure and function.	9.0541e-38
NZ_CP014485.1|WP_010642250.1|2031751_2032897_-|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	1.60988e-61
NZ_CP014485.1|WP_003950864.1|2035787_2036705_-|homoserine-kinase	gnl|CDD|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	7.46567e-104
NZ_CP014485.1|WP_003950863.1|2037098_2038157_-|threonine-synthase	gnl|CDD|236013	PRK07409, PRK07409, threonine synthase; Validated.	0
NZ_CP014485.1|WP_008409324.1|2029042_2029888_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl|CDD|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	4.68294e-107
NZ_CP014485.1|WP_061404216.1|2051703_2052840_-|Ku-protein	gnl|CDD|238408	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku homologs are predicted to form homodimers. It is proposed that the Ku homologs are functionally associated with ATP-dependent DNA ligase and the eukaryotic-type primase, probably as components of a double-strand break repair system.	4.28045e-112
NZ_CP014485.1|WP_078944235.1|2047718_2048615_-|RNA-polymerase-sigma-factor-SigF	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	5.88658e-111
NZ_CP014485.1|WP_015507099.1|2050888_2051683_+|class-I-SAM-dependent-methyltransferase-family-protein	gnl|CDD|371922	pfam12147, Methyltransf_20, Putative methyltransferase. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The family shows homology to methyltransferases.	2.11475e-76
NZ_CP014485.1|WP_033238097.1|2052913_2053819_+|ATP-dependent-DNA-ligase	gnl|CDD|240133	cd04863, MtLigD_Pol_like, MtLigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Mycobacterium tuberculosis (Mt)LigD. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required for non-homologous end joining (NHEJ)-mediated repair of DNA double-strand breaks (DSB). NHEJ-mediated DNA DSB repair is error-prone. MtLigD is monomeric and contains an N-terminal Pol domain, a central phosphoesterase module, and a C-terminal ligase domain. It has been suggested that LigD Pol contributes to NHEJ-mediated DNA DSB repair in vivo, by filling in short 5'-overhangs with ribonucleotides; the filled in termini would then be sealed by the associated LigD ligase domain, resulting in short stretches of RNA incorporated into the genomic DNA. The MtLigD Pol domain is stimulated by manganese, is error-prone, and prefers adding rNTPs to dNTPs in vitro. The MtLigD Pol domain has been shown to prefer DNA gapped substrates containing a 5'-phosphate group at the gap.	1.6082e-109
NZ_CP014485.1|WP_061404213.1|2044379_2045447_+|glycoside-hydrolase-family-43-protein	gnl|CDD|350141	cd18820, GH43_LbAraf43-like, Glycosyl hydrolase family 43 proteins similar to Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43 and Geobacillus thermoleovorans GbtXyl43B. This uncharacterized glycosyl hydrolase family 43 (GH43) subgroup belongs to a subgroup which includes enzymes with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55) and possibly bifunctional xylosidase/arabinofuranosidase activities, similar to Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43 and Geobacillus thermoleovorans IT-08 beta-xylosidase / exo-xylanase (GbtXyl43B). It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	9.83143e-94
NZ_CP014485.1|WP_015507096.1|2047157_2047643_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	4.99807e-07
NZ_CP014485.1|WP_015507097.1|2049131_2049935_+|DsbA-family-protein	gnl|CDD|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	1.57194e-30

Protein sequences

>NZ_CP014485.1|WP_061404212.1|2040981_2041956_-|hypothetical-protein
MTPADLSRAVLSAVRSAVDGGELAVAVPERVVVERPGPGGAGEWASNVALRLAREAGRPPREVAEVLRNRLVAAPGVAGVEVTGPGFLNVTLAGDSVGALVDRIAAEGEAYGSGDALREAAPVAVPDRSELRARIVAEAAGRLVRAQGGSVRGGGAAPVPARPGLDSEAVLGDDGLRWALLHPAPHDLPHGAEVLEQRARNPLFRVRYAHARSRGLVAGGDALGIVPGAGPVSGEAARVLTGLLGEQPAVLVAAARKGAPDRLARQLVTLADAFFDFHDSCDVLPRGGEKPGAAHRARLALAEAAGTVLAGGLSLLGISAPDHL
>NZ_CP014485.1|WP_003950861.1|2039570_2040962_-|diaminopimelate-decarboxylase
MSRSAHPAGPRHADVLPEGHYSAPAEDLNALDPKVWARTVRRDEDGVLTVGGLPVTRLAEEFGTPAFFLDETDFRARCRAWRDAFGADADVFYAGKAFLSRAVVRWLHEEGLNLDVCSGGELATALDAGMPAARIAFHGNNKTTAEIRRAVEAGVGRIVLDSFEEIVRVAHVADELGVRQPVQIRVTVGVEAHTHEFIATAHEDQKFGLALAGGQAAEAVRRALKLDGLELIGIHSHIGSQIFDMAGFEVSARRVVQLLAEVRDEHGVELPEIDLGGGLGIAYTSDDDPREPHEIAKALGEIVTRECESAGLATPRISVEPGRAIVGPTAFTLYEVGTVKPLEGLRTYVSVDGGMSDNIRTALYDAEYTVTLASRTSDAEPMLVRVVGKHCESGDIVVRDAFLPADLAPGDLLAVPATGAYCRSMASNYNHALRPPVVAVDEGAARVVVRRETEEDLLRLDVG
>NZ_CP014485.1|WP_078485248.1|2038163_2039456_-|homoserine-dehydrogenase
MMRTRPLKVALLGCGVVGSEVARIMTTHAADLAARIGAPVELAGVAVRRPDRVREGIDPSLVTTDATALVKRGDIDVVVEVIGGIEPARTLITTAFEHGASVVSANKALLAQDGAALHAAAEANGRDLYYEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTTNFILDKMDSTGAGYQEALDEATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVYREGMTEVTAADIASARRMGCTIKLLAICERAADGESVTARVHPAMIPLTHPLASVREAYNAVFVESEAAGQLMFYGPGAGGSPTASAVLGDLVAVCRNRLAASRGPGESAYTRLPVSPMGKVVTRYHISLDVADKPGVLAQVATVFAEHGVSIDTVRQTGKDGEASLVVVTHRAHDAALSGTVEALRNLDTVRGVASIMRVEGE
>NZ_CP014485.1|WP_003950863.1|2037098_2038157_-|threonine-synthase
MTHQWRGIIEEYRDRLPVSDTTPVVTLREGGTPLVPAQVLSERTGCEVHLKVEGANPTGSFKDRGMTMAISKAKEEGAQAVICASTGNTSASAAAYAVRAGMVSAVLVPQGKIALGKMGQALVHGAKILQVDGNFDDCLTLARALSEQYPVALVNSVNPVRIEGQKTAAFEIVDFLGDAPDIHVLPVGNAGNITAYWRGYREYAADAVSTRTPRMWGFQAAGSAPLVRGEVVKDPATIATAIRIGNPASWDYAIQARDESGGFIDEVTDRQILSAYRLLASQEGVFVEPASAASVAGLLKAAEQGKVDPGQRIVCTVTGNGLKDPDWAVAGAPQPLTVPVDATAAAERLGLA
>NZ_CP014485.1|WP_003950864.1|2035787_2036705_-|homoserine-kinase
MAGPAFRAAAVRVRVPATSANLGPGYDAFGLSLGLYDDVVVRVADSGLHIDIAGEGSETLPRDEDHLLVRAMRTAFDLLGGQPRGLEIVCANRIPHGRGLGSSSAAICAGIVAARAVTIGAEAKLDDAALLELATEIEGHPDNVAACLLGGFTLAWTESGAARAIRMEPDSSVVPVVFVPGKPVLTETARGLLPRTVPHVDAAANAGRAALLVEALTRRPELLLAATEDRLHQEYRAPAMPDSTALVERLRADGVPAVISGAGPTVLAFATDGAAEKVARLAGDGWAANRLALDLSGAGVLPLAP
>NZ_CP014485.1|WP_061404211.1|2033343_2035404_-|transcription-termination-factor-Rho
MSDTTDLMGVTADSTVDSAAAPATDASAAPAAGSRRRRGTGLEGMVLAELQQVASGLGIRGTARMRKSQLIEVIKEAQAGGGAAAPAKSEPEAAKPKRRATSKARTGEAEAAAEPAQKPAKAAEKKQAKVAEQAEPEAQQDSQQQIDIPGQGAGDEQPAGERRRRRATAEAGSPEQAEAKQERAAKQQDQKGEGRGDDGSGQQQDGGEGRRDRQNRRDRDRGDRERGDRSERGERGGRDRDRRKGDDGGQGGQGGGNRQQQGGGQNRDRHDDFDDDGGGRRGRRGRYRDRRGRRGRDEVGEPQVNEDDVLIPVAGILDILDNYAFIRTSGYLPGPNDVYVSLAQVRKNGLRKGDHVTGAVRQPKDGERREKFNALVRLDSVNGMAPESGRGRPEFNKLTPLYPQDRLRLETDPGVLTTRIIDLVSPIGKGQRGLIVAPPKTGKTMIMQAVANAITHNNPECHLMVVLVDERPEEVTDMQRSVKGEVISSTFDRPAEDHTTVAELAIERAKRLVELGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTALYPPKRFFGAARNIEDGGSLTILATALVDTGSRMDEVIFEEFKGTGNMELKLDRKLADKRIFPAVDVDASGTRKEEILLSGEELGIVWKLRRVLHALDQQQAIELLLDKMRKTQSNAEFLLQIQKTTPTAGGND
>NZ_CP014485.1|WP_010642250.1|2031751_2032897_-|LCP-family-protein
MAEQTSQDGDTPENGEEARRARRIRPTGQRRRPRSRRRKILLAAAWTAAGGILVGGAGLGFAYVKLNGNLEGVDINAALGSDRPEEVDDGSLDLLVLGSDSRSGDNGKYGRDEGAARSDTAMIVHLHEGRKKATVVSIPRDTLVTRPDCAAEDGSTVSGGQRQMFNTAYEAGGPACAVKTVEQMSGIRMDHYLEVDFSGFQEIIDRLGGVEVTTGKAIDDDKSGLHLDKGTHTLDGEQSLGLVRTRHGVGDGSDLGRIQLQQTFLTALMHRVQDMGLLSSPKKLYGVADAATKSLTTDAELDSVPALLDFAQGLKGLKPEGMEMLTLPVEYDPADANRVLPQEKAGAQVWKALRADKAVPASATEGSAGDKGDVDDVVSAG
>NZ_CP014485.1|WP_003950867.1|2031149_2031371_-|50S-ribosomal-protein-L31
MKRDIHPEYVETQVSCTCGAAFTTRSTIASGTVRADVCSECHPFYTGKQKILDTGGRVARFEARFGKAAGTKK
>NZ_CP014485.1|WP_003950870.1|2029928_2031005_-|peptide-chain-release-factor-1
MFEAVEELIGEHADIEKRLADPAVHADQAGARKLNKRYAELTPIVGTYRSWKQTGEDIETARELAADDPDFAAEVKELEAAREELTEKLRLLLVPRDPSDDKDVILEIKAGAGGDESALFAGDLLRMYLRYAERVGWKTELIDSTESELGGYKDVQVAVKTKGGQGATEPGQGVWARLKYEGGVHRVQRVPATESQGRIHTSAAGVLVTPEAEEIDVEINQNDLRIDVYRSSGPGGQSVNTTDSAVRITHLPTGVVASCQNEKSQLQNKEQALRILRSRLLAAAQEEAEREAADARRSQVRTVDRSEKIRTYNYPENRISDHRVGFKAYNLDQVLDGELDAVIQACVDADSAAKLAAA
>NZ_CP014485.1|WP_008409324.1|2029042_2029888_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MNLLLAEVAQATQRLADAGVPSPRNDAEELAAYVHQVKRGALHTVKDSDFDARYWEAIARREAREPLQHITGLAYFRYLELQVGPGVFVPRPETESVVGWAIDAVRAMDVVEPLVVDLCSGSGAIALALAQEVPRSTVHAVELSEDALVWTRKNVEGSRVHLHQGDAFGALPELDGQVDLVISNPPYIPLTEWEYVAPEARDHDPQMALFSGEDGLDTIRGIERTAHRLLRPGGIVVVEHADTQGGQVPWIFTEEKGWADAADHPDLNNRPRFATARKALP
>NZ_CP014485.1|WP_049977114.1|2043088_2044240_+|restriction-endonuclease
MAKVTVNGRPRRPAILIRSSPWKAGSEQTPWHDVFDMDNGHVRYFGDHKAGTTKPTGTTTGNAALLEAFEEHQAPTPEARAGAAPLLLFRAVSRDGRVKGFVEFCGVGVIERAERIVQWAGHEHTTFTNYVYDIALLDLTAENDQVDWDWITARRGTAVSDQDALAKAPRGWRDWTKRGHSALPRIRRRVAKARITKVRDQRPAPGSPRHKDLQFVYRQFDERKHDFEAVASAVAARVLRGTGHNYREGWITRRSGDGGADFVGRIDLGTGLAGTSLVVLGQAKCVRPESLVSAEQIARVVARLRRGWLGVYVTTGAFSEQAQLEMVEDQYPIVLVNGTDLARELRVMARDDHGDDLAACLNHILYVQGVPVAHRRPEEILLD
>NZ_CP014485.1|WP_061404213.1|2044379_2045447_+|glycoside-hydrolase-family-43-protein
MTSSRRIRALVGALLSCALAAGLGLATASPAAAGQVMRAADPSVIRVGSTYVSVQSAGGGLVVRQASSTEGLAGAEGRQVWADSAGLGEVWAPEIVRDGGRYHIYFAAGRGAAHRMYVISSDQADQGYGGATKLALPEDKWAIDGALFTFEGQRWFVWSGWEGDTDVEQNLYLARMNSPTEPTGPRYVISQPRESWERVVGNPFINEGPEPIMDPNGQLHIAYSANGSWSDQYCVADLRLRKGGDPTYVWDWYKSNGCLFGSHRETMMQGWDPTLYVDGPGHHSFVLLDGDIATSPPAGPRFPSMFHAVAKGTPYAWENRHWYTGTFTWWGETTYRRSGVPGAETDTGWSLKYFE
>NZ_CP014485.1|WP_061404214.1|2045470_2046886_-|NAD-dependent-succinate-semialdehyde-dehydrogenase
MTEQSKSTFATVNPATGRTVAEFPQIEGKEVDVRVQAAHLAFGEWRARTVEDRAAAVGRAGELLLERKEALAQIVTEEMGKLISEARGEVDLAASILTYYAKYGPEFAAPEPLDVEEGEAYLVSEPLGVLLGVMPWNFPLYQVVRFAGPNLVLGNTVLVKHAGICAQSALALEKIFQDAGLPPGAYTNLFVGHDEVSRIIDSRLVRGASLTGSEGAGAKVAERAGGNLKPSLLELGGSDVFLVLDGENLEHTVKAAAAGRLANTGQSCVAAKRFIVLDAHYDAFLDGLKSAFGRLVPGDPADESTTLGPLSSEGAAETLVEQIEETVRQGAELVMGGKRVDRPGAYVEPTILTGVEPGMRAYAEELFGPAAVVYRVADEDEAVALANDSEYGLGGTVFCADTDRARRVAERIETGMVWINHPTSTQADLPFGGIKRSGYGRELGHLGMREFVNRKLVRVLPPGTELHGIAG
>NZ_CP014485.1|WP_015507096.1|2047157_2047643_-|hypothetical-protein
MSPNPPIYDQLVREHGDVLTETRRVADQARLEAQSALDWSSILPPRRPEQQRPPQGPGPQGPGASGPGRPAAGMPAPRRAPGAPEGQQQGPGPQQRPAGPASAQGLAAVQNGGPQAPAGPRPAQGPPAPQGFAPRQGGPAAPQNGAPREEGQPEPGEEARA
>NZ_CP014485.1|WP_078944235.1|2047718_2048615_-|RNA-polymerase-sigma-factor-SigF
MSAQTEAGRQVKGTQAAPAGGPAAAADLPWVEDGGKIAPQDARDLSKIFFDRLQTLEEGTPEHQYARNTLIEMNLSLVRYAAGRFRHRGPGEMEDIVQVGTIGLIKAIDRFDLSREVEFTTFAVPYIVGEIKRFFRDTSWAVHVPRRLQELRVDMAKAKESLAAELDREPTVKELATKLERTEEEVVEGLVAANGYTAGSLDVPTESGDDNRAGGSPRSLADTLGAPDPAQELVEDLHALAPLLETLDERERRIVEMRFGQELTQSQIGAELGISQMHVSRLLSRILTRLRSGMLAEE
>NZ_CP014485.1|WP_015507097.1|2049131_2049935_+|DsbA-family-protein
MTSAPPAARPPSGSRHRRRKVVAALVLVAALVGGTFALTLDGSRDRERERAEQTATEASAGPEERDEALLRLARREKGDPMAVGDVDAPVVMIEYSDFQCPYCGRFARETKPALLREQVEEGVLRIEWRNFPLFGEESERAALAAWAAGQQGKFWEFHDLAYAEPRKRNSGAFSEKAVVDMAEKAGVGDLEQFRKDLGGAEGRAALERDQQEGSGLGVSSTPAFLVNGEPILGAQPGSTFTEAVEAAEADARSNSEAAGPDAEDGAK
>NZ_CP014485.1|WP_061404215.1|2049931_2050819_+|cytochrome-c-biogenesis-protein-CcdA
MTEAGLLMAFLGGLLALLSPCGALLLPAFFAYSFAGPTRLLLRTLFFYAGLCATLVPLGAAGALAGRLLTGHREVLVAVGGWTLVALGLAQILGLGFGSRRMQRAAGARRDGSALSVAALGAVYGLAGFCAGPILGSVLTVSAVGGDPVRGALLLAVYALGMAVPLFLLALAWDRFELGRRRWLRGRAVRLGPLTVHSTSAAGGLLFVLTGVAFLVFDGMASLGSVVDLETEYAWEERLAEVGALVSDRTVLLALCAVAAAGALAVLLRPGRRTAETAAEEPERAPEPARSGGGG
>NZ_CP014485.1|WP_015507099.1|2050888_2051683_+|class-I-SAM-dependent-methyltransferase-family-protein
MKRVWTTLKWTAARTVLRTVGRASRGIRIGYRFGFDSGVMLDHVYENRARGVLGVGRLIDRVFLDAVGWRAIRARRELLSRVLREEIGRREGEVFVLDVAAGPGRYLQDLVEQTPPGRLRVLCRDLAPAGLRKGEAMAAERGLTGITYEAGDALAPVAPEGRAPDVIVVSGLYELLLDDAEVRESIERLRGLLAEDGVLVFTTQTRHPQLELIAGVLTNRDGEPWVMKCRDMGQAEDWAALAGFKEVSSRRERVGLFTVTLCRA
>NZ_CP014485.1|WP_061404216.1|2051703_2052840_-|Ku-protein
MQSIWNGAISFGLVSIPVKLANATVSHAVSFRQIHTEDGGRIRYRKVCELEEKEVPSSEIGKGFEDADGSIIPITEEDLASLPLPTTRTIDIVAFVESERIDPLQMGNAYYLMVNGAPAAKPYALLREALRRSERVAIAKFALRGRERLGMLRVVDDVIAMHTLHWPDEIRSPEEAAPETDVTVRDAELDLADALMDTLGDVDLDSLHDDYREAVEEMVTAKAEGREPAPEKEPAQGEGTVIDLMSALESSVREAKRSRGEGEGEDTGEKGGENGGESGEKGKDAEVTSLSSRRRTGTRAKSSTGSGSGAKKKSSPARKKAAGGSGSGKSAASSSRGKSGSGRSSTAKKTASSGSGTKKTASSPTTKKKTASARKRSA
>NZ_CP014485.1|WP_033238097.1|2052913_2053819_+|ATP-dependent-DNA-ligase
MTPITHVEGRRLALSNLDKILYPATGFTKGEVLHYYASVAPVLLPHLRDRPLSFLRYPDGAGGESFFAKNVPPGTPDWVRVATVPRSARDTTSARQVVVDDLPSLMWAANLVTEFHTPQWRAEAPAVADRLVLDLDPGEPAGIAECCEVALMLRERLAADGLTAFAKTSGSKGLHLLAPLTGAPSREVTAYAKELAVAAGQAAPELVVHRMAKRLRGGKVFVDFSQNSASKTTATPYTLRARPHPTVSAPLTWEEVATRGEDDRLPGLRIEADEAAARVERYGDLLAPLVTGEAAAPLPGS

Crispr_ID: NZ_CP014485_9

• CRISPR_ID: NZ_CP014485_9
• CRISPR_location: 2431312-2431484
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014485_9

Consensus_repeat	Method
AAGATGGCCTCAAGCGCCGGCCGGGCTGGGAGCGACCCAGCT	PILER-CR

spacers of NZ_CP014485_9

>9.1|2431357|35|NZ_CP014485|PILER-CR
AAGGGGGCGGCCCGACCCCGCCGCCACGCGGCCTG
>9.2|2431437|24|NZ_CP014485|PILER-CR
GCTCCGATGCCCACGCGCACGTCA

CRISPR arrays and Neighbor proteins around NZ_CP014485_9

CRISPR arrays

The CRISPR arrays of NZ_CP014485_9

>merge|NZ_CP014485|9|2431312-2431484|PILER-CR
TGGCCTCAAGCGCCGGCCGGGCTGCGAGAAGGGGGCGGCCCGACCCCGCCGCCACGCGGCCTGAAGATGGCCTCAAGCGCCGGCCGGGCTGGGAGCGATCCGGCTGGGCTCCGATGCCCACGCGCACGTCAAAGACGGCCTCAAGCGCCGGCCGGGCTAGGAATGACCCAGCT

>NZ_CP014485|9|1|2431312-2431484|PILER-CR
TGGCCTCAAGCGCCGGCCGGGCTGCGAGAAGGGGGCGGCCCGACC	CCGCCGCCACGCGGCCTGAAGATGGCCTCAAGCGC
CGGCCGGGCTGGGAGCGATCCGGCTGGGCTCCGATGCCCACGCGC	ACGTCAAAGACGGCCTCAAGCGCC
GGCCGGGCTAGGAATGACCCAGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_008404581.1|2420815_2423113_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|132240
NZ_CP014485.1|WP_061404275.1|2423109_2425026_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224991
NZ_CP014485.1|WP_015507191.1|2440773_2441382_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP014485.1|WP_030770343.1|2426238_2427876_-|beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|119333
NZ_CP014485.1|WP_003950508.1|2433231_2434572_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|236486
NZ_CP014485.1|WP_079075981.1|2437492_2439880_-|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl|CDD|226482
NZ_CP014485.1|WP_003950506.1|2435562_2436993_-|NAD-dependent-malic-enzyme	unknown	unknown	gnl|CDD|223358
NZ_CP014485.1|WP_003950512.1|2428707_2429664_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP014485.1|WP_018469722.1|2429695_2431000_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270450
NZ_CP014485.1|WP_003950507.1|2434874_2435156_-|HU-family-DNA-binding-protein	unknown	unknown	gnl|CDD|259859
NZ_CP014485.1|WP_061404274.1|2417104_2418418_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP014485.1|WP_026048314.1|2418565_2420347_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223989
NZ_CP014485.1|WP_015507192.1|2441382_2442498_-|uroporphyrinogen-III-synthase	unknown	unknown	gnl|CDD|235981
NZ_CP014485.1|WP_100750291.1|2442671_2443730_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003950504.1|2440004_2440592_-|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NZ_CP014485.1|WP_015507187.1|2416381_2416924_-|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NZ_CP014485.1|WP_015507189.1|2432308_2432881_-|YqgE/AlgH-family-protein	unknown	unknown	gnl|CDD|234694
NZ_CP014485.1|WP_008404572.1|2427877_2428711_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP014485.1|WP_003950510.1|2431952_2432246_-|DUF3039-domain-containing-protein	unknown	unknown	gnl|CDD|378609
NZ_CP014485.1|WP_003950515.1|2425022_2425919_-|FAD-binding-domain-containing-protein	unknown	unknown	gnl|CDD|366378

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008404581.1|2420815_2423113_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|132240	TIGR03196, pucD, xanthine dehydrogenase D subunit. This gene has been characterized in B. subtilis as the molybdopterin binding-subunit of xanthine dehydrogenase (pucD), acting in conjunction with pucC, the FAD-binding subunit and pucE, the FeS-binding subunit. The more common XDH complex (GenProp0640) includes the xdhB gene which is related to pucD. It appears that most of the relatives of pucD outside of this narrow clade are involved in other processes as they are found in unrelated genomic contexts, contain the more common XDH complex and/or do not appear to process purines to allantoin.	7.44697e-166
NZ_CP014485.1|WP_061404275.1|2423109_2425026_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	1.13001e-54
NZ_CP014485.1|WP_015507191.1|2440773_2441382_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.00594e-21
NZ_CP014485.1|WP_030770343.1|2426238_2427876_-|beta-N-acetylhexosaminidase	gnl|CDD|119333	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. This GH20 domain family includes an N-acetylglucosamidase (GlcNAcase A) from Pseudoalteromonas piscicida and an N-acetylhexosaminidase (SpHex) from Streptomyces plicatus. SpHex lacks the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_CP014485.1|WP_003950508.1|2433231_2434572_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP014485.1|WP_079075981.1|2437492_2439880_-|UvrD-helicase-domain-containing-protein	gnl|CDD|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	4.70787e-61
NZ_CP014485.1|WP_003950506.1|2435562_2436993_-|NAD-dependent-malic-enzyme	gnl|CDD|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	4.78232e-170
NZ_CP014485.1|WP_003950512.1|2428707_2429664_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.76791e-65
NZ_CP014485.1|WP_018469722.1|2429695_2431000_-|extracellular-solute-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.12208e-90
NZ_CP014485.1|WP_003950507.1|2434874_2435156_-|HU-family-DNA-binding-protein	gnl|CDD|259859	cd14435, SPO1_TF1_like, Bacteriophage SPO1-encoded TF1 binds and bends DNA. This group contains proteins related to bacillus phage SPO1-encoded transcription factor 1 (TF1), a type II DNA-binding protein related to the DNA sequence specific (IHF) and non-specific (HU) domains. Type II DNA-binding proteins bind and bend DNA as dimers. Like IHF, TF1 binds DNA specifically and bends DNA sharply. Bacteriophage SPO1-encoded TF1 recognizes SPO1 phage DNA containing 5-(hydroxymethyl)-2'-deoxyuridine as opposed to thymine, Related family members includes integration host factor (IHF) and HU, also called type II DNA-binding proteins (DNABII), which are small dimeric proteins that specifically bind the DNA minor groove, inducing large bends in the DNA and serving as architectural factors in a variety of cellular processes such as recombination, initiation of replication/transcription and gene regulation. IHF binds DNA in a sequence specific manner while HU displays little or no sequence preference. IHF homologs are usually heterodimers, while HU homologs are typically homodimers (except HU heterodimers from E. coli and other enterobacteria). HU is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups).	9.32606e-39
NZ_CP014485.1|WP_061404274.1|2417104_2418418_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.66652e-57
NZ_CP014485.1|WP_026048314.1|2418565_2420347_-|DEAD/DEAH-box-helicase	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	3.7338e-59
NZ_CP014485.1|WP_015507192.1|2441382_2442498_-|uroporphyrinogen-III-synthase	gnl|CDD|235981	PRK07239, PRK07239, bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; Validated.	3.10948e-173
NZ_CP014485.1|WP_003950504.1|2440004_2440592_-|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	3.15972e-13
NZ_CP014485.1|WP_015507187.1|2416381_2416924_-|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	1.1624e-18
NZ_CP014485.1|WP_015507189.1|2432308_2432881_-|YqgE/AlgH-family-protein	gnl|CDD|234694	PRK00228, PRK00228, YqgE/AlgH family protein.	1.79008e-67
NZ_CP014485.1|WP_008404572.1|2427877_2428711_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.46131e-79
NZ_CP014485.1|WP_003950510.1|2431952_2432246_-|DUF3039-domain-containing-protein	gnl|CDD|378609	pfam11238, DUF3039, Protein of unknown function (DUF3039). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.92152e-35
NZ_CP014485.1|WP_003950515.1|2425022_2425919_-|FAD-binding-domain-containing-protein	gnl|CDD|366378	pfam00941, FAD_binding_5, FAD binding domain in molybdopterin dehydrogenase.	1.14535e-44

Protein sequences

>NZ_CP014485.1|WP_018469722.1|2429695_2431000_-|extracellular-solute-binding-protein
MKLLPRLAAPVAALVLAGLTATACAPQTSDTSSGKDEKTGDLRVWLFQEVNNGPKAKVVDRAVAAYEKAHEGSKVDVQYIPVDSRAEKIKAAFNDPSSAPDVIEYGNTDTAGYVRDGGLADISKEFAAWDEAADTDEAARASVTVDGKTYGAPYFVGVRALYYRTDLFEKHSVAVPETLDEVAAAAKKIRKAEPGLYGIAVGGAYTYGAMPFLWAHGGGLAEEKDGAYTSTLADKKSQAGIAAYTDLFGPDNCPAAKCAQMGGNDTVTAFAAGKAGMAIGGDFSHQAMEDGKVKGKYAVVPLPGTEKGEIAPAFAGGNNLGVLKSTERRSLAVDLVKELAGKKAQSELFDAMGFLPTFTDTRAEAAAEEPFVKPFVQTLDAGATFVPASPAWARIDSSLVLPTMFQEIVSGRKDVAAASRDAAKKMDDAFASAG
>NZ_CP014485.1|WP_003950512.1|2428707_2429664_-|sugar-ABC-transporter-permease
MTQTLTAPATPPVRKGGGGARPPRSGSRRPGWTPWLYLAPALVVLAGLLVYPVYQLGLISVLEYTQAQVSGGEPTSFQGLGNYRQLFTDPQFWQVLTATVVFAALCVLSTLFVGCAFAVLLTRIRALPRLALLIASLGAWATPAITGSTVWMFLFDADFGPVNRLLGLGDFSWTYGRYSAFALVLLEVVWCSFPFVMVTVYAGIRAVPTEVLEAASLDGASQWRVWRSVLAPMLRPILLVVTIQSVIWDFKIFTQIYVMTDGGGIAGQNLVLNVYAYQQAFASSEYSLGAAIGVVMLLILLAVTLVYLRLMRRQGEEL
>NZ_CP014485.1|WP_008404572.1|2427877_2428711_-|carbohydrate-ABC-transporter-permease
MKLVHRPWRLAAEAFALLAAVVVAFPLYWMVLSAFKPAGEIQSDTPRPWTLAPSLDSFRRVFQQEEFGRYFLNSLFVAGSVVVLSALIAFLAATAVTRFKFRFRTTLLIMFLVAQMVPVEALTIPLFFQMRDFGLLNTLGALILPHLAFSLPFAIWMLRGFVKAVPEALEEAALIDGASRTRFLWQILFPLVFPGLVATSVFSFISTWNDFLFAKSFIISDTSQSTLPMALLLFFKPEENDWGGIMAASTVMTVPVLVFFVLVQRRLVSGLGGAVKD
>NZ_CP014485.1|WP_030770343.1|2426238_2427876_-|beta-N-acetylhexosaminidase
MHHLIPAPRHHRPESGPETRLTLGPDTALRTGEGTGTAARWLRTTVGAATGLALPEAAAENPGPVVDLRITGEAGGLGAEAYRLTVSAEGVLIEGGDAAGVFWGAQTLRQLLGPDAFRRAPLNPGRAWQLGHVRIEDAPRFAWRGMMLDVARHFMPKDGVLRHLDLLAAHKLNVFHFHLTDDQGWRVDIRRHPELVRTGSWRPRSKWGHRASELWNDTPHGGYYTHDDIREIVAYAAERHITVVPEIEIPGHSQAAIAAYPELGNTDVTDTASLGVWDTWGINPHALAPTEDTLRFYEGVFEEVLELFPSRFIHVGGDECEKDEWRRSPAAQARIAELGVGDEDGLQSWFIRHFDRWLGARGRRLVGWDEILEGGLAEGATVSSWRGYAGGIAAARAGHDVIMCPEQQVYLNYREDGGPDEPVPIGYVRTLEDVYRFEPVPPELTGAEAAHVIGVQANVWTEVLENQDRVDYQLYPRLAALAEVAWSPLPASAERDFAGFDARMETHFRRLDALGVAYRPPSGPHPWQRRPGVLGRPFEGAPQPG
>NZ_CP014485.1|WP_003950515.1|2425022_2425919_-|FAD-binding-domain-containing-protein
MTTHAPQAAASVTLPASLDEAVAALAATPAAVPVAGGTDLMASVNAGQLRPTALVGLGRVREIRGWQYLDGHALLGAGLTHARMGRPDFAALIPALAAAARAAGPPQIRNAGTLGGNIATAAPSGDTLPVLAALEATLVVASPGGGRREVSVSHLLAGMDMLRGGELIGWVRVPLLHAPQVFLKATGRTGPGRATASVALVVDPARREVRCAIGAIAPMPLRPLEAERWAASLIDWDGERGLPQEALTAFGTYVATACVPDPEVPADGGEPPKLPPAVLHLRRTVAALARRALGRALS
>NZ_CP014485.1|WP_061404275.1|2423109_2425026_-|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MTDDERGEGTGAARGTSLSWGAIPHQGGEEYDDGATAFVQLPEGIADIPLAAPGQGYVPPITVTPATGPADPAATGVWSIPGAVAGGAPAPDPYAQQAGHGPDPYGTLPPQDVPEAAPGQVVADVYPDGAQVPGADGYPQPPADAFAATDAFGDTRPLTIPPGLSPDGPRPDLGAAFGGAERAGQPHGRPGIPGQQQGPGSAGQDATGHWDFTAALGESAPPAQGGTGQWAVPLAPEDVPEESGEYPLSEAAPRTGAWAAAPTHQAPATLPGGATAPWAGEAETTAPEPAPEAAPEASAEEAPGEAPGEAQGAPDGPEAEGQAESAPEADSAPKAADAPAPEPEAEAETEAEAEGAGEEPGGAVEAAGEEAPEAGGLHDERPVVSYTLNVNGIDRPVTEAWIGESLLHVLRERLGLAGAKDGCSQGECGACAVRVDGRVVASCLVPAATTEGSDIHTVEGLGAAEDGGPGEPSDVQRALARHCAVQCGFCIPGMAMTIHDLLEGNPRPTDLETRQALSGNLCRCSGYRAILESVRDVVGEREASAEAAADVAAHDDASAEAEDGEPAGADQAEVAIPHQAGPADGEAPGHPYGALPDGYDGLPQPPPSYDTGGYPPHHGQDGYGYDEQGPHEQHGGQA
>NZ_CP014485.1|WP_008404581.1|2420815_2423113_-|molybdopterin-dependent-oxidoreductase
MSHDTATGIPAQADAEAAPHGLGVSLPLAEARAKTEGTFPYAADLWAEGLLWAAVLRSPHAHARVVSIDTRQAAGMPGVHAIVTHEDVPGEGLHGRYGADRPVFASEVVRHHGEPLAAVAADHPDTARMAAAAIMVEYEVLPAQTDPEEAFTAEPLHPDGNVVRHIPLRHGDQEATGETVVEGVYRIGRQDPAPVGAEAGLAVPRPDGGVELYAASTDPHADRDRAAAVYGLDPERVKVVVTGVPGATADREDPGFLLPLGLLAMRTGCPVKLAATREESFLGHAHRHPTLLRYRHHADAEGRLVRVEAQILMDCGAYTDSSRESLAAAVAFACGPYVVPHATIDGWAVRTNNPPAGHVRGEGALQVCAAYEAQMDKLAKKLGLEPAEVRARNVLATGDVLPTGQTVTCPAPVAELLQAVQDFPLPALPKDTPEEEWLLPGGPEGAGEPGAVRRGVGYGLGMVHMLGAEGADEVSTATVRVQDGRATVICAAVETGQGFTTLARQIVQETLGIDEVAVAPVDTDQPPAGPSCHSRHTWVSAGAVERAAKMVRTQLLQPLAHQFGMSTELLQITDGKITSYDGVLSTTVTEAMDGKELWATAQCRPHPTEPLDGAGQGDAFVGLVFCAVRAVVDVDVEIGSVRVVELAVAQDVGRVLNPAQIAARIEAGLTQGLGAALTENLRAPQGVLRHPDLTGYALPTALDAPDIRIVRLVEERDVVAPFGAKAASAVPVVTAPAAVASAVRAASGRPVNRLPIRPQAAVAQS
>NZ_CP014485.1|WP_026048314.1|2418565_2420347_-|DEAD/DEAH-box-helicase
MTTSASHHLSPAFPGRAPWGTAGKLRAWQQAAMDKYVQEQPRDFLAVATPGAGKTTFALTLASWMLHHHVVQQVTVVAPTEHLKKQWAEAAARIGIKLDPEYSAGPLSKEYQGVAVTYAGVGVRPMLHRNRVEQRKTLVILDEIHHAGDSKSWGEACLEAFEPATRRLALTGTPFRSDTNPIPFVTYEEGNDGIRRSAADYTYGYGSALGDGVVRPVIFLSYSGQMRWRTKAGDEIAARLGEPMTKDAVSQAWRTALDPRGDWMPNVLRAADQRLTEVRKAIPDAGALVIATDQDQARAYAKLIREITGNKATLVLSDDSGASQRIDDFSKSDDRWMVAVRMVSEGVDVPRLAVGVYATTISTPLFFAQAVGRFVRSRRRGETASVFLPTVPMLLGFANEMEVERDHVLDKPKKDGEEDPYAESEKEMDEANKEQDEDTGEQEQFSFEALESEAVFDRVLFDGAEFGMQAHPGSEEEQDYLGIPGLLEPDQVQLLLQKRQARQIAHSRKKPDSEADLLELPAERRPVVSHKELLELRKQLNTLVGAYVHQTGKPHGVIHNELRRACGGPPSAEATAGQIRQRIDKVREWATRG
>NZ_CP014485.1|WP_061404274.1|2417104_2418418_+|MFS-transporter
MTITSTPGRTEPKKPSEPEEPEAHGDRRPVPPSDPSRRNGAVLVGFTAVTNLADGVMRLALPLLAVRLTDSPALVTTASLALTLPWLLTALHIGVVVDRFDRRMLLWLAGAARVAAMGGLFAAAVTGHLTLGRLLAAGAVLGVADVLAATAGSALVPAAVAREHRPRVNAWMVGAETVGQEFAGPFVGGLLLAAGTGLALGAIGVTYAAAALLLVLLAGRFRPAAPAPGTPAVPVNTRIAEGLRLLWRDPVLRTLSLTAAALNAVWGAWLALMPLHAHQAMGLGPGEYGFLLSGLGIGGLVGAATVTWVNRLLGPRRAMLADLLGTCAMTALPALTTSLWAVAAGAFLGGMGGTLWAVNSRTLTQHKVPDALLGRYTAASRLLCYGALPIGTAAAGLLAELLGTRTVFAVISVLALTTVIPFLRRVKAADLTGTSAP
>NZ_CP014485.1|WP_015507187.1|2416381_2416924_-|CGNR-zinc-finger-domain-containing-protein
MLATPALAALVEAFANTLDVDEVTDALATPEELAAWLREYEELDAPDAISPEAHRDYLALRAGLREEMGARVGDVPDPALLAAADEALAAHPVAVSVTGALRPAPGTPADRLPLTRLAIAWSSLVATGDAARLKRCAEHTCAWVFWDVSKNRSRRWCSMQVCGNRNKSRTYAARRRGEGG
>NZ_CP014485.1|WP_003950510.1|2431952_2432246_-|DUF3039-domain-containing-protein
MSTLEPERGAGTGTLVEPTPQTSSGDGDHERYAHYVQKDKIMASALDGTPVVALCGKVWVPGRDPKKYPVCPMCKEIYESMGPGGDKGKGGGDKDKK
>NZ_CP014485.1|WP_015507189.1|2432308_2432881_-|YqgE/AlgH-family-protein
MTEVSSLTGRLLVATPALADPHFDRAVVLLLDHDAEGSLGVVLNRPTPVGVGDILEGWGELAGDPGVVFQGGPVSLDSALGVAVIPGGPGCADPPLGWRPVHGAIGLVDLEAPPELLAAALGSLRIFAGYAGWGPGQLEEELVQGAWYVVESEPGDISAPRPEGLWRAVLRRQRSELAMIATYPDDPSLN
>NZ_CP014485.1|WP_003950508.1|2433231_2434572_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MTVNDDVLLVHGGTPLEGEIRVRGAKNLVPKAMVAALLGSAPSRLGNVPDIRDVRVVRGLLQLHGVTVRPGDEPGELVMDPSHVESANVADIDAHAGSSRIPILFCGPLLHRLGHAFIPGLGGCDIGGRPIDFHFEVLRQFGAKIEKRADGQYLEAPQRLRGTKIELPYPSVGATEQVLLTAVLAEGVTELSNAAVEPEIEDLICVLQKMGAIIAMDTDRTIRVTGVDKLGGYRHQALPDRLEAASWASAALATEGNIYVRGAQQRSMMTFLNTYRKVGGAFEIDDEGIRFWHPGGQLNAIALETDVHPGFQTDWQQPLVVALTQATGLSIIHETVYESRLGFTSALNQMGAHIQLYRECLGGSDCRFGQRNFLHSAVVSGPTRLQGADLVIPDLRGGFSYLIAALAAQGTSRVHGIDLINRGYENFLDKLVELGGKVELPGKALG
>NZ_CP014485.1|WP_003950507.1|2434874_2435156_-|HU-family-DNA-binding-protein
MNRSELVAALADRAEVTRKDADAVLAAFAEVVGDIVSKGDEKVTIPGFLTFERTHRAARTARNPQTGEPIQIPAGYSVKVSAGSKLKEAAKGK
>NZ_CP014485.1|WP_003950506.1|2435562_2436993_-|NAD-dependent-malic-enzyme
MATAPSVSYSMTVRLEVPASGTAVSQLTTAVESHGGSVTGLDVTASGHEALRIDVTIAASSTAHADEIVEGLRGIDGVVLGKVSDRTFLMHLGGKIEMASKHPIRNRDDLSMVYTPGVARVCMAIAENPEDARRLTIKRNSVAVVTDGSAVLGLGNIGPKAALPVMEGKAALFKRFAGIDAWPICLDTQDSDAIVEIVKAIAPGFAGINLEDISAPRCFEIEARLREALDIPVFHDDQHGTAIVVLAALTNALRVVGKSIGDVRVVMSGAGAAGTAILKLLLAAGVKHAVVADIHGVVHAGRDDLVGAEADSPLRWIADNTNPEGVTGTLKEAVVGADVFIGVSAPNVLDGADVAAMAEGAIVFALANPDPEVDPAVARETAAVVATGRSDFPNQINNVLVFPGVFRGLLDAQSHTVNTEMMLAAAGALADVVAEDEVNANYIIPSVFNDKVAGAVADAVSSAAKAVGAAPAPSAV
>NZ_CP014485.1|WP_079075981.1|2437492_2439880_-|UvrD-helicase-domain-containing-protein
MADVRDREISIEQDHLDQVYRRLEEKIHEAEFLMRDAARRGQVGTPGALAERDAQVFRAGIHLNRLNNEFEDFLFGRIDLLLGKDGEKGPDGAYTSVEPADDAVRPDGTADIAETLHIGRIGVLDADYAPLVIDWRAPAAAPFYRSTPVEPGRVVRRRVIRSKGRQVLGVEDDLMRPELTARLDGEPLAVVGDGALMAALGQARSHTMRDIVASIQAEQDRVIRAPAASVTLVEGGPGTGKTAVALHRAAYLLYQDRRRYAGGILIVSPTPLLVSYTEGVLPSLGEEGQVAIRALGSLVDGAEATAYDTPAAARAKGSARMVQVLRRAARGALDLGTARPAPAGEDEEREEVPEGQLDLGLPAPAGPPERLRVVAFGRRIELDAAELGRIRRNALSGTAPVNLLRPRARRLLLDALWARSGASGRHQDPELAAELRSGFDEDILSEDSFAAFLDAWWPELTPRAVLAAMADEKRLARWSRKVLNQGEVRRVARSLARLGPMGEGPLSVHDVALLDELEAVLGAPPRPRRKREADPLDHLTGLQELMPVREETQWERAERLAQERTEYTHVIVDEAQDLTPMQWRMVGRRGRQATWTVVGDPAQSSWSDPDEAAEARDEALGRRPRRRFTLTVNYRNPAEIAELASRVLALAMPGSDSPRAVRSTGVEPRFVVAGERMGETVRAEAARLLETVDGTIGVVVPMERREQAARWVAGLGERVVALGSLEAKGLEYDATVVVSPAEVADESPAGLRVLYVALTRATQELTVVSGRRDQPDADGVPDLLRDDVPAELLGE
>NZ_CP014485.1|WP_003950504.1|2440004_2440592_-|CGNR-zinc-finger-domain-containing-protein
MTGHAYRAGASARVLRFDCGRVCLDLAATAHPVERLDGPDRLRQWLAGAGLVPPGTPLERAGPGWLAAFRDLRTQIAAVVGAELDGRPPGHALDRVNAVARNPPPPPRAVRRADGTLGRGLSGDPDCQALLGAVARDAVDLLTDPGARALLRRCAGQDCPLVYLDTSRGRRRRWCSGETCGNRERVARHRRSRRG
>NZ_CP014485.1|WP_015507191.1|2440773_2441382_+|GNAT-family-N-acetyltransferase
MSMPAFLPAGPGLSLRPWRARDARELIDAYRDPLLRQFTRTWPEDEAGARAWLAREEAGARDGSRYSFAVELAAQAPDGTGPAPSGVRDPAATGLLAGCVVLKVFPHDDDRPARTDTAEVGYWTTASVRGRGLAGRAVLALADWAFTALPALTRLELLHQVDNEPSCRVAEKAGFPHHETLAPQPPVFPLPGHVHVRPRPAA
>NZ_CP014485.1|WP_015507192.1|2441382_2442498_-|uroporphyrinogen-III-synthase
MGEASPLVGFTVGVTAERRAQELGALLGRRGAEVVYAPALRVVPLADDRELREATEELVARPPEIVVASTAVGFRGWVEAAEGWGVGGALREALGGARLLARGPKVTGAVRAAGLREEWSPRSEAMEEVRERLLADGVAGLRVAVQLHGEPVPGFAEALRAAGAEVVGVPVYRWLPPADLTPVDRLVDATVRRTLDALTFTSAPAVVSVLRRAEALGLREALVDAVNGDVAVVCVGPVTARPLQEAGVEPVQPERYRLGPMVQRLCEELPARTPELAVAGHRVQLRGHAVLVDGEARPVPPAPMALLRALARRPGRVVARAELLRALPGAGRDEHAVESATARLRTALGAPELVRTVVKRGYRLAVDDPEG
>NZ_CP014485.1|WP_100750291.1|2442671_2443730_-|hypothetical-protein
MLMRPKTGMPVAAACAIVLLLPGSAAAFGEGGERGSGPSGSTDGKGKVSAGVSQIRISQVKGGGSGKQGNLAPIDADWEPPACWYEPVFTPEELKEFVDRTGGHGDVGIHQSWYGKGLWTDHYRDGEVQDNMDDDRTEAEGYKNYNIGKDGNFWRSVAPDDSHPDSWDCGRIMFWAPDNQVPQIPNAPTPQMLAEYAYEHVKVPDTEVEVRPQARSTVNLPTWVWLDKGKFEDVVVRAELPRTNLYAETTAHPVSLTLEPGTEDAETFPADGTCRINDDGSIGSPYKKGSADQDPPCGITYLRASDKPYQLSASITWEISWEGTGGTGGDLPDGTFETTQDMTVQEIQSINR

Crispr_ID: NZ_CP014485_10

• CRISPR_ID: NZ_CP014485_10
• CRISPR_location: 2534943-2535026
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_10

Consensus_repeat	Method
TGGCCGCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP014485_10

>10.1|2534966|38|NZ_CP014485|CRISPRCasFinder
CATTTGGGCTCGGTCCGATCGGCGGTGCCGCCTACCGA

CRISPR arrays and Neighbor proteins around NZ_CP014485_10

CRISPR arrays

The CRISPR arrays of NZ_CP014485_10

>merge|NZ_CP014485|10|2534943-2535026|CRISPRCasFinder
TGGCCGCAAGCGCCGGCCGGGCTCATTTGGGCTCGGTCCGATCGGCGGTGCCGCCTACCGATGGCCTCAAGCGCCGGCCGGGCT

>NZ_CP014485|10|9|2534943-2535026|CRISPRCasFinder
TGGCCGCAAGCGCCGGCCGGGCT	CATTTGGGCTCGGTCCGATCGGCGGTGCCGCCTACCGA
TGGCCTCAAGCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_008415646.1|2538780_2540397_-|lactate-permease-LctP-family-transporter	unknown	unknown	gnl|CDD|224535
NZ_CP014485.1|WP_061404309.1|2538206_2538839_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP014485.1|WP_061404310.1|2543439_2547186_-|glycosyltransferase	unknown	unknown	gnl|CDD|224137
NZ_CP014485.1|WP_061404305.1|2526358_2527363_-|stage-II-sporulation-protein-M	unknown	unknown	gnl|CDD|376676
NZ_CP014485.1|WP_061404307.1|2528378_2529002_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_010642863.1|2531926_2533090_-|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl|CDD|185085
NZ_CP014485.1|WP_061404303.1|2517001_2518204_+|DUF4350-domain-containing-protein	unknown	unknown	gnl|CDD|379527
NZ_CP014485.1|WP_008415642.1|2535333_2536008_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|378924
NZ_CP014485.1|WP_003950440.1|2534622_2534805_-|hypothetical-protein	unknown	unknown	gnl|CDD|225391
NZ_CP014485.1|WP_003950436.1|2540634_2541030_-|DUF3499-domain-containing-protein	unknown	unknown	gnl|CDD|378788
NZ_CP014485.1|WP_008415638.1|2530834_2531806_-|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl|CDD|223131
NZ_CP014485.1|WP_061404304.1|2518200_2519181_+|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786
NZ_CP014485.1|WP_061404306.1|2527434_2528364_+|RDD-family-protein	unknown	unknown	gnl|CDD|224628
NZ_CP014485.1|WP_003950432.1|2547821_2548085_-|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP014485.1|WP_003950444.1|2529143_2530598_-|adenosylhomocysteinase	unknown	unknown	gnl|CDD|377487
NZ_CP014485.1|WP_008415654.1|2548937_2549450_+|cysteine-dioxygenase-family-protein	unknown	unknown	gnl|CDD|380416
NZ_CP014485.1|WP_049978950.1|2541901_2543443_-|hypothetical-protein	unknown	unknown	gnl|CDD|377520
NZ_CP014485.1|WP_061404308.1|2536698_2538081_-|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl|CDD|236557
NZ_CP014485.1|WP_003950441.1|2533210_2534368_-|bifunctional-glucose-6-phosphate/mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|378434
NZ_CP014485.1|WP_010642870.1|2541470_2541854_+|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240574

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008415646.1|2538780_2540397_-|lactate-permease-LctP-family-transporter	gnl|CDD|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	6.11682e-139
NZ_CP014485.1|WP_061404309.1|2538206_2538839_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.55473e-13
NZ_CP014485.1|WP_008415642.1|2535333_2536008_+|alpha/beta-hydrolase	gnl|CDD|378924	pfam12697, Abhydrolase_6, Alpha/beta hydrolase family. This family contains alpha/beta hydrolase enzymes of diverse specificity.	5.61803e-09
NZ_CP014485.1|WP_061404310.1|2543439_2547186_-|glycosyltransferase	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.75845e-33
NZ_CP014485.1|WP_061404305.1|2526358_2527363_-|stage-II-sporulation-protein-M	gnl|CDD|376676	pfam01944, SpoIIM, Stage II sporulation protein M. SpoIIM is on e of four stage II sporulation proteins that is necessary for the forespore inside the mother-cell to be properly internalized through the breakdown of peptidoglycans trapped between the membranes of the septum separating the forespore and the mother-cell. The four proteins working in sequence are SpoIIB, pfam05036, SpoIIM, SpoIIP, pfam07454, and finally SpoIID, pfam08486. D, M and P are in a complex with each other and the complex assembles in a hierarchical manner such that M, which serves as a membrane anchor, recruits P to the septum and P, in turn, recruits D to the septum.	2.08339e-40
NZ_CP014485.1|WP_010642863.1|2531926_2533090_-|mannose-6-phosphate-isomerase,-class-I	gnl|CDD|185085	PRK15131, PRK15131, mannose-6-phosphate isomerase; Provisional.	1.3309e-108
NZ_CP014485.1|WP_061404303.1|2517001_2518204_+|DUF4350-domain-containing-protein	gnl|CDD|379527	pfam14258, DUF4350, Domain of unknown function (DUF4350). This domain family is found in bacteria, archaea and eukaryotes, and is approximately 70 amino acids in length.	0.000357356
NZ_CP014485.1|WP_061404306.1|2527434_2528364_+|RDD-family-protein	gnl|CDD|224628	COG1714, COG1714, Predicted membrane protein/domain [Function unknown].	1.39897e-18
NZ_CP014485.1|WP_003950440.1|2534622_2534805_-|hypothetical-protein	gnl|CDD|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	2.99279e-13
NZ_CP014485.1|WP_003950436.1|2540634_2541030_-|DUF3499-domain-containing-protein	gnl|CDD|378788	pfam12005, DUF3499, Protein of unknown function (DUF3499). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.	8.96775e-53
NZ_CP014485.1|WP_008415638.1|2530834_2531806_-|cation-diffusion-facilitator-family-transporter	gnl|CDD|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	4.01716e-40
NZ_CP014485.1|WP_061404304.1|2518200_2519181_+|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.50159e-100
NZ_CP014485.1|WP_061404308.1|2536698_2538081_-|phosphomannomutase/phosphoglucomutase	gnl|CDD|236557	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed.	0
NZ_CP014485.1|WP_003950432.1|2547821_2548085_-|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	5.22363e-28
NZ_CP014485.1|WP_003950444.1|2529143_2530598_-|adenosylhomocysteinase	gnl|CDD|377487	pfam05221, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.	0
NZ_CP014485.1|WP_008415654.1|2548937_2549450_+|cysteine-dioxygenase-family-protein	gnl|CDD|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.38817e-23
NZ_CP014485.1|WP_049978950.1|2541901_2543443_-|hypothetical-protein	gnl|CDD|377520	pfam05506, DUF756, Domain of unknown function (DUF756). This domain is found, normally as a tandem repeat, at the C-terminus of bacterial phospholipase C proteins.	0.00424477
NZ_CP014485.1|WP_003950441.1|2533210_2534368_-|bifunctional-glucose-6-phosphate/mannose-6-phosphate-isomerase	gnl|CDD|378434	pfam10432, bact-PGI_C, Bacterial phospho-glucose isomerase C-terminal SIS domain. This is the C-terminal SIS domain of a bacterial phospho-glucose isomerase EC:5.3.1.9 protein which is similar to eukaryote homologs to the extent that the sequence includes the cluster of threonines and serines that forms the sugar phosphate-binding site in conventional PGI. This domain contributes a good proportion of the active catalytic site residues. This PGI uses the same catalytic mechanisms for both glucose ring-opening and isomerisation for the interconversion of glucose 6-phosphate to fructose 6-phosphate. It is associated with family SIS, pfam01380.	4.58355e-16
NZ_CP014485.1|WP_010642870.1|2541470_2541854_+|metallopeptidase-family-protein	gnl|CDD|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	4.12898e-26

Protein sequences

>NZ_CP014485.1|WP_003950440.1|2534622_2534805_-|hypothetical-protein
MALEAGLLEILACPACHAPLEESKTDSTPELLCTGEGCALAYPIRDGIPVLLVDEARRPA
>NZ_CP014485.1|WP_003950441.1|2533210_2534368_-|bifunctional-glucose-6-phosphate/mannose-6-phosphate-isomerase
MFDETLLDDPEALTRADPRGLLRDAAGAGARVRTAARLAAEAGITELHPDGRPRTVLIAGPGTAATATADLLGTLAGGACPVVPLGPTGVAAAAGALRWTLPGWAGPVDLLLIATPDGGEPGLALLAEQAYRRGCTVVAVAPDRTPVSEAVQGAHGLAVPMATAPGELPEEEPVEAYANGTTAASGAFWALLTPLLLLLGRTGLVDADTDAVHDLADRLDTTAERCGPAVAAYSNPAKTLAAELAESLPLVWTEGPGAGPIGRRFTALLAEVAGHPALTAALPEALPAHGALLVSGIADASDPDDFFRDRVDEPEPLRARVVLLRDRPPGGLTAAPAARELALAHNTALSELEPGEGSDLAATAELIATTDFAAVYLALATTPRS
>NZ_CP014485.1|WP_010642863.1|2531926_2533090_-|mannose-6-phosphate-isomerase,-class-I
MDRLQNTVRPYAWGSVTAIPHLTGTEPTGEPQAELWMGAHPGAPSLVDRGTGPRSLAELIAADPDRELGPAVAARFGPQLPFLLKLLAADAPLSVQVHPDSDQAAAGYADEEQRGVPRTAPERNYKDPHHKPELICALTPFEGLCGFRDPAEAADTLAALDLDSLKPYVDLLHAHPEEAALREVLTAVLTADRDEMAATVTEAAAASARLGGPHATYADLARHYPGDPGVLAAMLLNQVSLQPGEALYLGAGVPHAYLSGLGVEIMAASDNVLRCGLTPKHIDVPELLRIVRFDPATPAVLRPEASPDGEEVYDTPVHDFRLSRYVLAPGAPVRDLTLPTPQILLGTEGSPTVGELPLGPGQSVFVPAGEPVELRGPGTVFRATALT
>NZ_CP014485.1|WP_008415638.1|2530834_2531806_-|cation-diffusion-facilitator-family-transporter
MSASGGTKAIVAALSANLAIAVAKFVAFLFSGSSSMLAESVHSLADSGNQGLLLLGGKRAKRQATPEHPFGYGRERYIYAFLVSIVLFSVGGMFAIYEGYEKIKHPHELEHWYWPVGVLVFAIIAEAFSFRTAIKESNPLRGKQSWSQFIRRAKAPELPVVLLEDFGALVGLILALGGVGLALATGDGVWDGIGTLCIGVLLIVIAIVLAAETKSLLLGESAGLDEVRKIEAALVDGDTVTRVIHMRTLHLGPEELLVAAKLAVQHDDTAAEVAAAINAAEARIREAVPIARAIYLEPDIYDEAAAARGTNPAMTPSPDASPR
>NZ_CP014485.1|WP_003950444.1|2529143_2530598_-|adenosylhomocysteinase
MASAQQHDFKVADLSLAEFGRKEITLAEHEMPGLMSIREEYAASQPLAGARVTGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAIAVGPNGTPDNPQGVPVFAWKGESLEEYWWCTEQALTWPNTPTGGPNMILDDGGDATLLVHNGVQYEKDGKVPDPVTAESDEHRVILQLLTRTLGENPQKWTQLASEIRGVTEETTTGVHRLYEMQRDGQLLFPAINVNDAVTKSKFDNKYGCRHSLIDGINRATDVLIGGKTAVVCGYGDVGKGCAESLRGQGARVIVTEIDPICALQAAMDGYQVATLDDVIGQADIFVTTTGNKDIIMAADMAKMKHQAIVGNIGHFDNEIDMAGLAAIPGIVKDEVKPQVHTWTFPDGKVIIVLSEGRLLNLGNATGHPSFVMSNSFADQTLAQIELFTKPDEYPTDVYVLPKHLDEKVARLHLDALGVRLTTLRPEQAAYIGVSVEGPFKPDHYRY
>NZ_CP014485.1|WP_061404307.1|2528378_2529002_-|hypothetical-protein
MPKGRYSLHDPHDHTPLAEEHFHCAPGPHGWRYVAQLTTPATENDHLGSVDLTLDDLGRPLRLELHSGGWQVRGGALEGVTWVRTDPTGEEATEGTVAAHTFTGNSPAFLVATARLLRLTTTSPPTRVRLVSFTGQALAPRTLDQQWALRSSETHATDNGPLTVDEYLVGDVETGEQHTVHLAGDVILSAPGVELEDLETPPTRFTD
>NZ_CP014485.1|WP_061404306.1|2527434_2528364_+|RDD-family-protein
MAGGEAETVSGPVTGEAVALELRPAKLLSRGAAVLIDLAVTWLVFLLVMVGVLVTTASLDEAAVAAVSVAVFLLVPVGGPIAVETLSHGRSLGKWACGLRVVREDGGPIRFRHALVRGAMAVVEILLTVGVVACVASLVSERGRRVGDVFAGTLVVRERIPVARAPELAAPEPWLAQQVNGLDLSSVPDSLWLAVRQYLGRARQLDAQVAAGMAGRLAEELAVRTGVPVPAGVPAGSYLAAVAYERRERERRKVGVLPRDVAEGEVPGGGAGAVPEARGVGEEISPAEGGGGGEGRSGGQAGTGFVPPV
>NZ_CP014485.1|WP_061404305.1|2526358_2527363_-|stage-II-sporulation-protein-M
MDLDVFVAAHEAEWRRLGTLLRRRRLTGPEADELVSLYQRATTHLSLISSAAPDPQLTGRLTRLVALARSKVTAPRRARARDLTGFLAHDFPAALYRTRTWWAPTAVASLLVAALIGWWVATHPEVRSAIAAPAELRELTRPGGDYEAYYSSHPATSFAAQVWTNNAQAAALCLVLGAFLCLPVVAVLLPNMVNIGVGIGLMASAGRLDTFLGLLVPHGLLELTAVLVAAGTGLRLGWTVIDPGPRRRRDALAQEGRAALGMALGLALVLLVSGVIEAFVTPSGLPTWARITIGAAAEAAFLVYVYAVGGRAARAGRTGDLTADETGSGVPVAT
>NZ_CP014485.1|WP_061404304.1|2518200_2519181_+|MoxR-family-ATPase
MSAPTPDADGATEARAALEAVRAEIGKAVVGQDPVVTGLVIALLCRGHVLLEGVPGVAKTLLVRALAAAVELETKRVQFTPDLMPSDVTGSLVFDARTSEFSFQPGPVFTNLLLADEINRTPPKTQASLLEAMEERQVTVDGTARHLPEPFLVAATQNPVEYEGTYPLPEAQLDRFLLKLNVSLPPRDDEIALLSRHARGFDPRDLSAAGLHPVAGPAQLDAARSAVAGTSVSPEIAAYIVDVCRATRDSPSLSLGASPRGATALLSTARAWAWLTGRDYVIPDDVKALALPTLRHHVQLRPEAEMEGVTPDAVLTSLLARVPVPR
>NZ_CP014485.1|WP_061404303.1|2517001_2518204_+|DUF4350-domain-containing-protein
MTSPAPVSSRLSRLWVRSRGVLLAVLLIVVAGITLAALQQGDKSGELDPSSYDPQGSRALAALLAHDGIRVQPVDSLTALRERAGPDTTLLVTVPDRLTGEQQSALRSTAAEADARLVLVTPGTSSLTGLAPGTEARPPAERSAIAPACAFPAAQRAGTADVGGLRYSTDASGAERCYPSDGLPSLLRLPVRAPATEGTPGVPETVLLGSSDILHNNRLDEHGNASLALQLLGSRPHLLWYLPSAPDASAAPEEPRGFLELVPDGWRWATLQLCFAAVLAAIWRGRRLGPVVSEDLPVVVRASETTEGRARLYHRADARDQAAALLRGASRARLAELTGVAAADADAPEVLLPALTALLKSRSPGQDPASLLFGPAPTDDAGLVRLADQLDALEREVRTS
>NZ_CP014485.1|WP_008415642.1|2535333_2536008_+|alpha/beta-hydrolase
MGGVVLVHGLYHQAGHFGVVAAGLRRVGVEVVVPELHRGSLREDTRVVQEAVDGFGVAPVVVGHSYGGSVITGVRGAGHLVYLAAFVLDAGESAAEWGGGSAALREAVVAAGEEGATRLRPELAAGVLYDDCPAPLARRAVGLLREQGPGCGRGVPERQGWRTTPSTYVVCARDRAIDPGVQRRMAARCGEVREWPTGHSPFVGRPELVVGLVREVLAGIGGRG
>NZ_CP014485.1|WP_061404308.1|2536698_2538081_-|phosphomannomutase/phosphoglucomutase
MTADLSQIVKAYDVRGVVPDQWDEHLSALFGAAFAQVTAVPAGSGAIVVGHDMRPSSPGLSHAFARGAAEQGLDVVEIGLCSTDQLYYASGALDLPGAMFTASHNPAQYNGIKLCRAGAAPVGQDTGLADIRALVESWLDDPASAPAPAATPGTLSRRDTLADYAAYLRSLVDVSGIRPLKVVVDAGNGMGGHTVPTVLGDLPLTVVPLYFELDGTFPNHEANPLDPKNLVDLQARVRAEGADLGLAFDGDADRCFVVDERGEPVSPSAVTALVAARELARNGGHGTVIHNLITSWSVPEVVREHGGTPARTRVGHSFIKAEMAATGAIFGGEHSAHYYFRDFWNADTGMLAALHVLAALGGQPAPFSTLVAEYDRYPASGEINSTVTDQQATTARVRVAYADHPAATTDTLDGLTVTTPDWWFNLRPSNTEPLLRLNVEARDRQTLERLTTEVLELVRQ
>NZ_CP014485.1|WP_061404309.1|2538206_2538839_+|GNAT-family-N-acetyltransferase
MTWVREMVVGDAAAVSAVRVAGWRAAYAGVIPGAYLDAMSVERDAARREERFAAGRAAGLCDLVAVGADGQVAGWACCGPRDTPADGPGAGEGELYALYVRPGLLGRGVGRALLGAVHEEAAARGWGALVLWVVEANARARRFYEAAGYRADGGAQSEEYAGVAVREVRYRRPAGPFPGGPGQPSGVRRTGSRAASTPGPPCSAPPRSGT
>NZ_CP014485.1|WP_008415646.1|2538780_2540397_-|lactate-permease-LctP-family-transporter
MFVQPLEPVADSLPLSALVAALPLVTVLVLLGAVRMKAHLAGALGLAVAALVAWLVYGMPLGQTLSSAAQGALFGLFPIMWIVVNALWVYRMTVRTQHFDILRRSFGRLSDDPRIQALVIAFCFGALLEALAGFGAPVAISAVMLVALGFDPVRAAVVALVANTAPVAFGAMGTPVVTLAQVTGLPLDSVASVVGRQTPLLALVVPLVLIWLVDGRRGLRETWLPALVCGVAFAAAQFLAANYFSAQLADIAAALAGAAALMLVPSARRPADEAVRASVLKGVRSDDLDHDDPRPEIYRAYAPYALIVAVFSLAQIPPVKELLAKATQSFDWPFLDVADADGQPVGANIFTLPLVATGGTLVLVAGLLTAVVLGVRAKDALREWGATVHELRFAILTVVSVLALAYVMNLSGQAATIGYTVAAAGAGLAFLSPVLGWFGVAVTGSDTSANALFGALQVTAARESGLSAELLAAANSSGGVLGKMISPQNLTIACAAVGLAGKEGDLLRKVLPWSLGLLLVMCLIVVGQSTAVLGWMLP
>NZ_CP014485.1|WP_003950436.1|2540634_2541030_-|DUF3499-domain-containing-protein
MSPVRRCSRTACGRPAVATLTYVYADSTAVLGPLATYAEPHCYDLCAEHSERLTAPRGWEVVRLADSAGPARPRGDDLEALADAVREAARPQDRPAAPGHRTPDPAPRPAPDPQLPATRRAHLRVLRSPDS
>NZ_CP014485.1|WP_010642870.1|2541470_2541854_+|metallopeptidase-family-protein
MRGPVAPPQVPLSASRAQVFDDFVRDAVERLERHVPQIADIDFVVQEVPRPQGPGDDWQDEAVPLGAALEARKGRPAQVVVYRRPVEIRAKGRDERALLVHEVVVEQVADVLGLTPEAVDPRYGEGE
>NZ_CP014485.1|WP_049978950.1|2541901_2543443_-|hypothetical-protein
MKRTTLSLIAAGAALAAVTSVAAVAAPEEGPAATGKAAQQPVERTSLLCPAPSSSELAETTYTAYTPKTEVSSDSGTAALVPAARSLAGKDDKKDDEKDDKGDKGDEKGEEEKPFLAVKKQGAPVTAEENGSGAPALIGLAEGSLAPGWSAQQTTHFTAGAGRGLHGAACSAPDTDFWFPGASTAEDRSDYLHLTNPDDAAAVVDIELYGKDGALDSEVGEGIQVPPRSSVPVLLSTLTGKPQTNLTVHVTARSGRVAAAVQALDQKVGGDWLTPSAEPSASVVLPGIPKDATAVRLVAFAPGSADADLKVSLAGPNGSLSPAGNETLHLKSGMTTAVDLADVTRGEPGSLVLTPTGDSGETPVVAAVRVIRGKGADQESAFIPAARPVGDRATVTGNGAKGTYLSLTAPGKAAKVRVTASAGTGGGTAATKTYSVGAGRTLAADVPLPDSLKGTYALTVETVSGGPVHASRTLTLSGAAADGISMFTVQNLTDDRGTVTVPAARPEMGVLLD
>NZ_CP014485.1|WP_061404310.1|2543439_2547186_-|glycosyltransferase
MSVHSHSAAYPAASAGSMSDPAATMTATPTSLPGLDPTSAPAYARHVVTAVLVTHDGARWLPDALAGLLAQERPVQNAVAADTGSADDSARLVADAFGDDRVLHLARRTGFGTAVDEAVRAAGVLTPDDLPYLKRPGGWDPVARQWHDENYDLPELPYGEPEQWLWLLHDDCAPAPDALAGLLAAVEAEREAGGEVAIVGPKLRGWYDRRQLLEVGVTIAHSGRRWTGLDRREQDQGQHDHVRPVLSVSTAGMLIRRDVYEELGGFDRALPLMRDDVDLCWRAQAAGHRVLIAPDAVLRHAEAASRERRTVDCAGRGTTSPHRVDKAGAVHTLLVNSRGAALPWVLLRLVVGTVARTLAYLVGKVPGQAVDEISGLLGTLLRPGRILNARRRRGKGTVEPAELRPLFPPPGATVRATVEQVAGNLTRGSDADAPGAGRHGGAVESGPGGDDADFLEVEQFARLKRLARRPGPVLFAVLLLASLVACRALLGGGALAGGALLPVPDQLGDLWGRYADGWHAVGTGTTEPAPPYLALLATLAALLFGSTHTAVTVVLVASVPLAGFAAYLASGSLVPSRLLRAWGSVVYAFLPAVTGALAGGHLGTAVLAVLLPVMARAGLSAAGLLGHPGTWRATWAYTLLLTLATAFTPMVWPLALVLGIGVLVVRRSALGTYAPRFVAQFATPLLVLAPWSLTLLPFGFFQTAGLDTATGGAGPLDLLGASPGGPGTLSAVLFLGVVAAALGALLREERRRAILTAWAVALTALLFAVLANASAWAGPATLVQGAALLGAALVGADGARHRVAEQSFGWRQPLAALIALACALGPAAAALTWMAAGADGPLERRDPVQVPAFVAEESRTQDQARTLVLAGDSAAEVSYALVRGSGGRLGDAELAAAAGTDDRLSTVVARLVAGSGADQADQLGGFAVRYVLVRDGSPREMSRVLDSTPGLTRLSQQDGSALWRVDRQVSRAAVVAKDGSGEPLPVAAGPVELHTDLPAGPAGRVLRLADTADPGWTATLDGEPLERVTVDDWAQGFTLPEGGGRLDVTFEDPFTHTVWIWTQGFLGLVLVVLALPGRRRTVDDDMPDEPAPVPAQPVEGEGRRARRLRAQAEAEAEDAAPEADIPEQREAPGDEPDPAWTAAPEPYEPVEPQQGGYDPYGYQNQGYDQSPQGYPPQTGYDPNAYDPYQQQPQDPYQQGGWQQGQQGYPGYEQQPQQGYGPGQAAPEYGQYEQPPHGHGRERPDGSQQ
>NZ_CP014485.1|WP_003950432.1|2547821_2548085_-|WhiB-family-transcriptional-regulator
MTELFEQLLVEEADEELGWQERALCAQTDPESFFPEKGGSTREAKKVCLACEVRSECLEYALANDERFGIWGGLSERERRRLKKAAV
>NZ_CP014485.1|WP_008415654.1|2548937_2549450_+|cysteine-dioxygenase-family-protein
MNQDSDLQIAGDLLEVQHLLRPAPEHPSTVAGFVRLARTVAADRARWAPLVAYDPTSRWYHRLETGPGYEVWLLSWLPGQGSGAHDHGRSAGVMTVLDGALTEHTPGGRQVLRPGGHRVVAPGHAHEVVNDALEPAVSLHVYFPGLTTMPVRTLERSATTPAEEPARLTH

Crispr_ID: NZ_CP014485_11

• CRISPR_ID: NZ_CP014485_11
• CRISPR_location: 2553143-2553281
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014485_11

Consensus_repeat	Method
GTGGCCTCAATCGCCGGCCGGGCT	PILER-CR

spacers of NZ_CP014485_11

>11.1|2553167|39|NZ_CP014485|PILER-CR
CGGTGACCGGCGGCTGAGGCGCCGTCTCAGCCCCACGAC
>11.2|2553230|28|NZ_CP014485|PILER-CR
TCAGCCTGGCCGGCGCTTGAGGCCAAGG

CRISPR arrays and Neighbor proteins around NZ_CP014485_11

CRISPR arrays

The CRISPR arrays of NZ_CP014485_11

>merge|NZ_CP014485|11|2553143-2553281|PILER-CR
AGCCCGGCCGGCGATTGAGGCCATCGGTGACCGGCGGCTGAGGCGCCGTCTCAGCCCCACGACAGCCCGGCCGGCGCTTGAGGCCACTCAGCCTGGCCGGCGCTTGAGGCCAAGGAGCCCGGCCGGCGTTTGAGGCCAC

>NZ_CP014485|11|2|2553143-2553281|PILER-CR
AGCCCGGCCGGCGATTGAGGCCAT	CGGTGACCGGCGGCTGAGGCGCCGTCTCAGCCCCACGAC
AGCCCGGCCGGCGCTTGAGGCCAC	TCAGCCTGGCCGGCGCTTGAGGCCAAGG
AGCCCGGCCGGCGTTTGAGGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_008415646.1|2538780_2540397_-|lactate-permease-LctP-family-transporter	unknown	unknown	gnl|CDD|224535
NZ_CP014485.1|WP_079055426.1|2558694_2560416_+|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP014485.1|WP_049978950.1|2541901_2543443_-|hypothetical-protein	unknown	unknown	gnl|CDD|377520
NZ_CP014485.1|WP_061404316.1|2566278_2567811_+|cryptochrome/photolyase-family-protein	unknown	unknown	gnl|CDD|225588
NZ_CP014485.1|WP_079075986.1|2557062_2558370_+|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP014485.1|WP_008415654.1|2548937_2549450_+|cysteine-dioxygenase-family-protein	unknown	unknown	gnl|CDD|380416
NZ_CP014485.1|WP_061404314.1|2562788_2564177_+|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP014485.1|WP_008415660.1|2553374_2554466_-|NDP-sugar-synthase	unknown	unknown	gnl|CDD|224129
NZ_CP014485.1|WP_008417606.1|2564220_2564775_-|acyl-CoA-thioesterase	unknown	unknown	gnl|CDD|224523
NZ_CP014485.1|WP_003950436.1|2540634_2541030_-|DUF3499-domain-containing-protein	unknown	unknown	gnl|CDD|378788
NZ_CP014485.1|WP_061404311.1|2551740_2552847_-|hypothetical-protein	unknown	unknown	gnl|CDD|223200
NZ_CP014485.1|WP_008415656.1|2550407_2551712_+|coenzyme-F420-0:L-glutamate-ligase	unknown	unknown	gnl|CDD|183957
NZ_CP014485.1|WP_049978955.1|2556152_2556905_+|TIGR03089-family-protein	unknown	unknown	gnl|CDD|274426
NZ_CP014485.1|WP_061404315.1|2564978_2566157_+|LCP-family-protein	unknown	unknown	gnl|CDD|224235
NZ_CP014485.1|WP_061404312.1|2554585_2555995_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|128941
NZ_CP014485.1|WP_061404310.1|2543439_2547186_-|glycosyltransferase	unknown	unknown	gnl|CDD|224137
NZ_CP014485.1|WP_003950432.1|2547821_2548085_-|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP014485.1|WP_031178234.1|2560497_2562420_+|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP014485.1|WP_010642870.1|2541470_2541854_+|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240574
NZ_CP014485.1|WP_003950429.1|2549454_2550411_+|2-phospho-L-lactate-transferase	unknown	unknown	gnl|CDD|237443

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008415646.1|2538780_2540397_-|lactate-permease-LctP-family-transporter	gnl|CDD|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	6.11682e-139
NZ_CP014485.1|WP_079055426.1|2558694_2560416_+|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	8.72267e-55
NZ_CP014485.1|WP_049978950.1|2541901_2543443_-|hypothetical-protein	gnl|CDD|377520	pfam05506, DUF756, Domain of unknown function (DUF756). This domain is found, normally as a tandem repeat, at the C-terminus of bacterial phospholipase C proteins.	0.00424477
NZ_CP014485.1|WP_061404316.1|2566278_2567811_+|cryptochrome/photolyase-family-protein	gnl|CDD|225588	COG3046, COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only].	8.00847e-154
NZ_CP014485.1|WP_079075986.1|2557062_2558370_+|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	9.02928e-62
NZ_CP014485.1|WP_008415654.1|2548937_2549450_+|cysteine-dioxygenase-family-protein	gnl|CDD|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.38817e-23
NZ_CP014485.1|WP_061404314.1|2562788_2564177_+|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	3.50084e-54
NZ_CP014485.1|WP_008415660.1|2553374_2554466_-|NDP-sugar-synthase	gnl|CDD|224129	COG1208, GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis].	1.83472e-98
NZ_CP014485.1|WP_008417606.1|2564220_2564775_-|acyl-CoA-thioesterase	gnl|CDD|224523	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism].	1.03667e-48
NZ_CP014485.1|WP_003950436.1|2540634_2541030_-|DUF3499-domain-containing-protein	gnl|CDD|378788	pfam12005, DUF3499, Protein of unknown function (DUF3499). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.	8.96775e-53
NZ_CP014485.1|WP_061404311.1|2551740_2552847_-|hypothetical-protein	gnl|CDD|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	9.14159e-20
NZ_CP014485.1|WP_008415656.1|2550407_2551712_+|coenzyme-F420-0:L-glutamate-ligase	gnl|CDD|183957	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional.	0
NZ_CP014485.1|WP_049978955.1|2556152_2556905_+|TIGR03089-family-protein	gnl|CDD|274426	TIGR03089, conserved_hypothetical_protein, TIGR03089 family protein. This protein family is found, so far, only in the Actinobacteria (Streptomyces, Mycobacterium, Corynebacterium, Nocardia, Propionibacterium, etc.) and never more than one to a genome. Members show twilight-level sequence similarity to family of AMP-binding enzymes described by pfam00501.	1.7579e-75
NZ_CP014485.1|WP_061404315.1|2564978_2566157_+|LCP-family-protein	gnl|CDD|224235	COG1316, LytR, Transcriptional regulator [Transcription].	8.38565e-57
NZ_CP014485.1|WP_061404312.1|2554585_2555995_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|128941	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.	4.1864e-48
NZ_CP014485.1|WP_061404310.1|2543439_2547186_-|glycosyltransferase	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.75845e-33
NZ_CP014485.1|WP_003950432.1|2547821_2548085_-|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	5.22363e-28
NZ_CP014485.1|WP_031178234.1|2560497_2562420_+|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	2.07754e-42
NZ_CP014485.1|WP_010642870.1|2541470_2541854_+|metallopeptidase-family-protein	gnl|CDD|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	4.12898e-26
NZ_CP014485.1|WP_003950429.1|2549454_2550411_+|2-phospho-L-lactate-transferase	gnl|CDD|237443	PRK13606, PRK13606, LPPG:FO 2-phospho-L-lactate transferase; Provisional.	4.5399e-174

Protein sequences

>NZ_CP014485.1|WP_061404311.1|2551740_2552847_-|hypothetical-protein
MATPAPSSLAPRASTLWRMAGRFPPRPRAPYGTSEGTPCPDTGPDPTGARTFRAATRAAAAARPEAPARSRAWTPPYQADLGLILGVLRRGPGDPAFRLTQDRAVWRASRTPEGPATLRVTLRAGRAEATAWGPGADWFLDRLPALLGAADTPEAFTPRHRLVADSARRATGLRLTRTGLVLESLIPSVLEQKVTADEAYRAWRRLLTRHGEPAPGPAPERMAVMPDPRAWSLIPSWEWHRAGVDDKRAATILRAVRLHSRLERAAGLPPEKAAALLEAVPGIGPWTSAEVVQRTHGAPDAVTTGDLHLPGIIGYALTGDRTTDDAAMLELLAPYAGQRHRAARLILLAGRVPPRRTPKMPYSDISRL
>NZ_CP014485.1|WP_008415656.1|2550407_2551712_+|coenzyme-F420-0:L-glutamate-ligase
MSAAPAFQVRAVPGLPEVDEGDDLAKLIAAAAPTLADGDIVLVTSKIVSKAEGRVLAADSREAAIDAETVRVVARRGALRIVENRQGLVMAAAGVDASNTPAGTVLLLPEDPDASARALRAGLADALGVDVGVVVTDTFGRPWRNGLTDVAIGSAGVRVLDDLRGGTDAHGNPLHATVIALADELAAAGDLVKGKSEGLPVAVVSGLSALVGGEEGAGARELVRGAADDMFRLGTSEAVREAVTLRRTVRSFTDEPVDPGAVRRAVAAAVTAPAPHHTTPWRFVLLESAASRTRLLDAMRDAWIADLRRDGKSEESIAKRVRRGDVLRNAPYLVVPCLVMDGSHAYPDERRSAAEREMFVVATGAGVQNFLVALAGEQLGSAWVSSTMFCREVVREVLDLPDTWDPMGAVAVGRAATPPADRPGRDPETFLTVR
>NZ_CP014485.1|WP_003950429.1|2549454_2550411_+|2-phospho-L-lactate-transferase
MRIVVLAGGIGGARFLRGLKAAAPDADITVIGNTGDDIHLFGLKVCPDLDTVMYTLGGGINEEQGWGRTDETFQVKDELKAYGVGPDWFGLGDRDFATHIVRTQMLGAGYPLSAVTEALCERWQPGVRLLPMTDDRVETHVAVDLDGERRAVHFQEYWVRLRASVDALAVVPVGAEQSKPAPGVLEALAEADVVLFPPSNPVVSIGTILAVPGIREAIAEAGVPVVGLSPIVGGAPVRGMADKMLSAIGVETAAAAVAEHYGSGLLDGWLVDSADTGAVAEVEAAGIRCRAVPLMMTDLDATAAMAREALALAEEVRA
>NZ_CP014485.1|WP_008415654.1|2548937_2549450_+|cysteine-dioxygenase-family-protein
MNQDSDLQIAGDLLEVQHLLRPAPEHPSTVAGFVRLARTVAADRARWAPLVAYDPTSRWYHRLETGPGYEVWLLSWLPGQGSGAHDHGRSAGVMTVLDGALTEHTPGGRQVLRPGGHRVVAPGHAHEVVNDALEPAVSLHVYFPGLTTMPVRTLERSATTPAEEPARLTH
>NZ_CP014485.1|WP_003950432.1|2547821_2548085_-|WhiB-family-transcriptional-regulator
MTELFEQLLVEEADEELGWQERALCAQTDPESFFPEKGGSTREAKKVCLACEVRSECLEYALANDERFGIWGGLSERERRRLKKAAV
>NZ_CP014485.1|WP_061404310.1|2543439_2547186_-|glycosyltransferase
MSVHSHSAAYPAASAGSMSDPAATMTATPTSLPGLDPTSAPAYARHVVTAVLVTHDGARWLPDALAGLLAQERPVQNAVAADTGSADDSARLVADAFGDDRVLHLARRTGFGTAVDEAVRAAGVLTPDDLPYLKRPGGWDPVARQWHDENYDLPELPYGEPEQWLWLLHDDCAPAPDALAGLLAAVEAEREAGGEVAIVGPKLRGWYDRRQLLEVGVTIAHSGRRWTGLDRREQDQGQHDHVRPVLSVSTAGMLIRRDVYEELGGFDRALPLMRDDVDLCWRAQAAGHRVLIAPDAVLRHAEAASRERRTVDCAGRGTTSPHRVDKAGAVHTLLVNSRGAALPWVLLRLVVGTVARTLAYLVGKVPGQAVDEISGLLGTLLRPGRILNARRRRGKGTVEPAELRPLFPPPGATVRATVEQVAGNLTRGSDADAPGAGRHGGAVESGPGGDDADFLEVEQFARLKRLARRPGPVLFAVLLLASLVACRALLGGGALAGGALLPVPDQLGDLWGRYADGWHAVGTGTTEPAPPYLALLATLAALLFGSTHTAVTVVLVASVPLAGFAAYLASGSLVPSRLLRAWGSVVYAFLPAVTGALAGGHLGTAVLAVLLPVMARAGLSAAGLLGHPGTWRATWAYTLLLTLATAFTPMVWPLALVLGIGVLVVRRSALGTYAPRFVAQFATPLLVLAPWSLTLLPFGFFQTAGLDTATGGAGPLDLLGASPGGPGTLSAVLFLGVVAAALGALLREERRRAILTAWAVALTALLFAVLANASAWAGPATLVQGAALLGAALVGADGARHRVAEQSFGWRQPLAALIALACALGPAAAALTWMAAGADGPLERRDPVQVPAFVAEESRTQDQARTLVLAGDSAAEVSYALVRGSGGRLGDAELAAAAGTDDRLSTVVARLVAGSGADQADQLGGFAVRYVLVRDGSPREMSRVLDSTPGLTRLSQQDGSALWRVDRQVSRAAVVAKDGSGEPLPVAAGPVELHTDLPAGPAGRVLRLADTADPGWTATLDGEPLERVTVDDWAQGFTLPEGGGRLDVTFEDPFTHTVWIWTQGFLGLVLVVLALPGRRRTVDDDMPDEPAPVPAQPVEGEGRRARRLRAQAEAEAEDAAPEADIPEQREAPGDEPDPAWTAAPEPYEPVEPQQGGYDPYGYQNQGYDQSPQGYPPQTGYDPNAYDPYQQQPQDPYQQGGWQQGQQGYPGYEQQPQQGYGPGQAAPEYGQYEQPPHGHGRERPDGSQQ
>NZ_CP014485.1|WP_049978950.1|2541901_2543443_-|hypothetical-protein
MKRTTLSLIAAGAALAAVTSVAAVAAPEEGPAATGKAAQQPVERTSLLCPAPSSSELAETTYTAYTPKTEVSSDSGTAALVPAARSLAGKDDKKDDEKDDKGDKGDEKGEEEKPFLAVKKQGAPVTAEENGSGAPALIGLAEGSLAPGWSAQQTTHFTAGAGRGLHGAACSAPDTDFWFPGASTAEDRSDYLHLTNPDDAAAVVDIELYGKDGALDSEVGEGIQVPPRSSVPVLLSTLTGKPQTNLTVHVTARSGRVAAAVQALDQKVGGDWLTPSAEPSASVVLPGIPKDATAVRLVAFAPGSADADLKVSLAGPNGSLSPAGNETLHLKSGMTTAVDLADVTRGEPGSLVLTPTGDSGETPVVAAVRVIRGKGADQESAFIPAARPVGDRATVTGNGAKGTYLSLTAPGKAAKVRVTASAGTGGGTAATKTYSVGAGRTLAADVPLPDSLKGTYALTVETVSGGPVHASRTLTLSGAAADGISMFTVQNLTDDRGTVTVPAARPEMGVLLD
>NZ_CP014485.1|WP_010642870.1|2541470_2541854_+|metallopeptidase-family-protein
MRGPVAPPQVPLSASRAQVFDDFVRDAVERLERHVPQIADIDFVVQEVPRPQGPGDDWQDEAVPLGAALEARKGRPAQVVVYRRPVEIRAKGRDERALLVHEVVVEQVADVLGLTPEAVDPRYGEGE
>NZ_CP014485.1|WP_003950436.1|2540634_2541030_-|DUF3499-domain-containing-protein
MSPVRRCSRTACGRPAVATLTYVYADSTAVLGPLATYAEPHCYDLCAEHSERLTAPRGWEVVRLADSAGPARPRGDDLEALADAVREAARPQDRPAAPGHRTPDPAPRPAPDPQLPATRRAHLRVLRSPDS
>NZ_CP014485.1|WP_008415646.1|2538780_2540397_-|lactate-permease-LctP-family-transporter
MFVQPLEPVADSLPLSALVAALPLVTVLVLLGAVRMKAHLAGALGLAVAALVAWLVYGMPLGQTLSSAAQGALFGLFPIMWIVVNALWVYRMTVRTQHFDILRRSFGRLSDDPRIQALVIAFCFGALLEALAGFGAPVAISAVMLVALGFDPVRAAVVALVANTAPVAFGAMGTPVVTLAQVTGLPLDSVASVVGRQTPLLALVVPLVLIWLVDGRRGLRETWLPALVCGVAFAAAQFLAANYFSAQLADIAAALAGAAALMLVPSARRPADEAVRASVLKGVRSDDLDHDDPRPEIYRAYAPYALIVAVFSLAQIPPVKELLAKATQSFDWPFLDVADADGQPVGANIFTLPLVATGGTLVLVAGLLTAVVLGVRAKDALREWGATVHELRFAILTVVSVLALAYVMNLSGQAATIGYTVAAAGAGLAFLSPVLGWFGVAVTGSDTSANALFGALQVTAARESGLSAELLAAANSSGGVLGKMISPQNLTIACAAVGLAGKEGDLLRKVLPWSLGLLLVMCLIVVGQSTAVLGWMLP
>NZ_CP014485.1|WP_008415660.1|2553374_2554466_-|NDP-sugar-synthase
MTQAPEAILLVGGKGTRLRPLTVRTPKPMVPAAGVPFLTHQLARARAAGVEHVVMATSYLAEVFEPYFGDGSDLGLHLEYVTEEEPLGTGGAIRNVAPRLHSGPDDPVLIFNGDILTGLDIPALVATHQESGADVSLHLSRVEDPRAFGLVPTDEAGRVLAFLEKPQTPEEIVTDQINAGAYVFRRSVIDTIPTGRPVSVERETFPGLLESGAHLQGMVDSTYWLDLGTPQAFVRGSADLVLGRAPSPAVPGRRGESLVLDGAHVAPDAKLSEGTVVGVGAHVGAGARITGSTLLDGAYVAEGAVVTDSLIGAGARVGARTHVTGAVIGDGADAGADNELRDGLRLWCDAVLPDGGVRFSPDR
>NZ_CP014485.1|WP_061404312.1|2554585_2555995_-|N-acetylmuramoyl-L-alanine-amidase
MTCAAALALPAALPSGALAATAAHPRAGAADTSTGAPAADALPAAPPGAHSLPAADDTPGHTRSLPLPDAPAGRSSEPGEGPDERVLSPREVEPFSLLGVVWDDPDAHLEGRVQVRTRSTVTGAWSGWQELESHHDDHGADRSTPEGAAGRGATAPLWVGRSDAVELRVTARDDHRHQGERTTDRLPEGLRLDLVDPGEAPAPEEEPAPRPTRAGAPVATPAGLPAAAGEPAVLPELTREETLAELEAARAVEEPEAGAAGPQQRAQPYVGPRPKIVTRKGWGADEKLREKNFAYTGKVKAAFVHHSATGNNYTCAQAPSVIRGIYRYHTQSSGWRDLGYNFMVDKCGTVYEGRAGGVDKAVLGAHTLGFNSNSTGIAVLGSYSSVKPPKAAVDAVAKLTAWKLGLSGANPKGKVTLTSGGSNLYAKGKKVSLHVISGHRDGYSTECPGTRLYGQLGTARSASARLQGR
>NZ_CP014485.1|WP_049978955.1|2556152_2556905_+|TIGR03089-family-protein
MNAIDRTPADLLRSALAADPARPLVTFYDDATGERVELSVATFANWVAKTANLLQGDLSAEPGDRLALLLPAHWQSAVWLLACHSTGVVAEVGGDPAAADLVVSGPDTLDAARACSGERIALALRPLGGRFPHAPEGFADYAVEVPGQGDRFAPFAPVEPDEPALAVAGRELTGAELVEEARAEAARLGLGPSDRVLSGLGWETWEGLAAGLYAPLAAGGSVVLCRNTGGLSEEGLARRVADERVDLTLL
>NZ_CP014485.1|WP_079075986.1|2557062_2558370_+|LCP-family-protein
MTDRAGRPDGQGDEGNDEANQETAGSGAREQGAHWGPRPARQGPARRPFLRRRWVWWTAAGTTVALVGAGVGAWALYDRLQGNITRDDAVIAELERHEKERPLPSKQGALNILLVGSDTRAGQGNGQYGVARGQRSDTVIMLHLAADRRSATAMSIPRDLMVEIPSCRRADGESTPARTAQFNDAYSYGGTACTIRTVERLTRIRVDHHMVVDFQGFKRMVDAVDGVRICLKQPMDDKDAHVRLPAGEHTLNGEQSLGFVRARKSLGNGSDTDRMERQQQFLGALVAKVQSNGVLLNPGKLYPLLDAATSSLTTDPSLSSLIDLYDLVRSMRNIPTKEVRFLTVPREAYAGDPNRDQLVEPAASELFTLLREDEPVRIAPRPSDSASPAPSASPTGTGPAAPSASRAPSGTPGVRSTPVPDPTFSGNSAARSACE
>NZ_CP014485.1|WP_079055426.1|2558694_2560416_+|LCP-family-protein
MRLSPSDGRPPGNGRRGAVPRSRRAPDREHPQPGQERPRRPAPEHDDPEPGSRPSRETVPGQRRRRGAEPEPPPGRAAARRAGGRKGRGQKQKKGKKKVLLWTGGVLAFVMVALAASAYAYLEHLKDNINSVADDGAGTGGFSKDRAINVLLIGTDKRSGEGNEGYGDKDSPGHADTTFVLHVSKDRSNATALSIPRDLITDIPDCPTQQEDGTETVIPGKQGTKFNESLGQSERTPSCTMRTVTELTGIKMDHFMVADFNAVKTLTTAVGGVEVCLAKDIDDPDSHLKLSKGTHTIEGEEALAFVRTRHSVGFGGDLSRIEIQQQFLSSLMRKLSSNDTLTSPTKMFSLAEAGTKALTVDSTLADISKLRDLGMELGKLDPKNLTFATIPVKDNPAEPTPVTVVLDDPKAQSVFQMVREDVSFTAVKKKEKKEKAAVAARLKGERADPTEVRVDVYNGGAATGSAQTTLTWLQNTQGVLKSTQLGNAPEELAKTTVEYGEEEAPQARALADMMGLPASALKPGESVSNSQGLPAVKLTLGRDFKGAGIPLVAPKEAPKGVNKVSADKTVCAK
>NZ_CP014485.1|WP_031178234.1|2560497_2562420_+|LCP-family-protein
MGSARSEGGPERDQDPAGALGWDEGLYEGRDAAVETGRAKVPGQRGAGDAGGADGESETEPEDPDEQPDRDSGTPMGVPEQPGPPAGESGPGRRRPEAGGERDAPEEAPEEAPDEAPGDASGEAPEEADAEAAAKPRKPKRRKRRILAWTAAGLALTLVAAGTAGWFYYQHLNDNLDRKPLHIGKSRAPEPTPNAAGQTPLNILLIGSDARDSEENQRLGGARETFGGPALADVQMLLHLSADRSHMSVISMPRDTLLKIPECTDPESGKVYPATVGTRMTNQTLMRGGPGCTVATWEELTGIRIDHFMMVDFAGVVSMADAIGGVPVCVDANLHSRTSDGKGSGLKLKKGTTEIKGEDALAWLRTRYGFGDGSDIARAKAQHMYMNSLVRKLRENTGLSSPNKLRNLAEEATEALTVDEELASVAELYALAEELKKVAPNRTTMATMPWIWSPSDHNRVEPKPDDAEQLFRLVREDIALDGRDGDGPSPSPSEDETSEDPADDPADIAVLVRNGTGSPVAAPVSGRASDLVKLLTEAGFTRATADQNQVENREETAILYPSAELEGDAQSVAEALGMPLGTVRKSAEVSGVTLEIGADWTEGDTFPKPKKGDNEPPDSAEALNGSDDTACMEVDPAFTW
>NZ_CP014485.1|WP_061404314.1|2562788_2564177_+|LCP-family-protein
MRAVTALSVAVLASSGVGHAVMSGLDSGIERVDPFKDMKNRPEAGRGLNILLAGTDGRDTITEEQRQAYRLGGKPCHCTDTLMLLHLSADHSRVSVVSLPRDSYAMMPPHTDRTSGEEHRPHPVKLNAAYAEGGPELTVRTVEKMTEVKIDHYVEVDFTSFMETVDAVGGVEICTVRRLKDSYTGLDLAPGPHRLDGGQALQYVRSRHLDGTGDLSRMQRQQRFLAALTAEVTGSGVLLNPVRFREVAQSVLGSLRADSGFTTERMLDLGKAMRGFTPASAEFTSVPVQEEAREVPAVGNTLVWKAKEAKRIFGALREDRPLADHDSARSKATVVDVPPEQIRVQVENGTPRQGLGAQADRALRATGFGTSGQAVDAADRATARTTVLYDPRWDRSARTVAAAFPGAELKAAPGQGGTLRVVLGADFTEVHPVRAEDPPEGATGALRGDEVTCPRPEAAGKA
>NZ_CP014485.1|WP_008417606.1|2564220_2564775_-|acyl-CoA-thioesterase
MTDPARVPESEIPGKPTSASRTTLSHIMTHNDTNLLGTVHGGVIMKLVDDAAGAVAGRHSEGPAVTASMDEMAFLMPVRVGDLLHVRAQVNWTGRSSMEVGVRVVAERWNDSTPAQQVGTAYLVFTAVDADGKPRQVPPVIPETERDKRRYQEAQIRRTHRLARRRAILDLREQRAAEGLDADD
>NZ_CP014485.1|WP_061404315.1|2564978_2566157_+|LCP-family-protein
MPHVRRRQAPPPAAPPRTTVPPQPQYGRPGGRDDYDDGYNTGQVYGGGGRGGGGYQDGPGGPGGRRPAPNWGRRVKVGLITFLVAALVVSVGTYMWASSKLRGEVDLAKVIERPEEGEGTNYLIVGSDSRDGMTDDDKKRLHTGSAEGKRTDSMMILHVGSNGNTMVSLPRDSEVEIPSFKGSESGKLFPAQGRRVKLNAAYAEDGPELLVRTVEYNTGLRIDHYAEIGFGGFANIVDALGGVEMDIPKAFKDKKSGADFQAGKQTLDGEQALAFVRTRYAFAGSDLDRTKNQQKFLATLANQAATPSTVLNPFRLYPTLGAGLDTLIVDKDMGLFDLAGMFWAMKGLTGGEGTSMNMPISGSNGGNLVWDKAKKDQLMQQLRNDEKVTVTE
>NZ_CP014485.1|WP_061404316.1|2566278_2567811_+|cryptochrome/photolyase-family-protein
MGQRSGGKGTGAVHWLFGDQLGPHFLTPGEDGPHRDTPLVMIESRAVFRRRRFHRAKAHLVLSAMRHRAAELGDRVTYVKAGTYREGLRKAAGKRPVTVHHPTSRAALALVDALPQVTVLPARGFLVGHQEFADWAEGRGGRALRQEDFYRRTRAAHDLLMEGDRPASGRWNLDHDNREPPPRDAGALDVPAPYRPREDAIDEEVRHDLDRWERSGEVTFVGRDGPRHFPATRREALNALRRFVSDRLATFGPYEDAMLTADPVMSHSLLSSSLNLGLLDPAECVERAEAAWRAGEAPLNSVEGFVRQIAGWREYIWHLYWHFGEEYRTTNALGHHAPLPDWWSDLDADAVTAHCLSTVLAQLRDTGWTHHIPRLMVLGNYALQRGWDPAALTDWFHRCFVDGYDWVMLPNVLGMSQYADGGRMTTKPYASGGAYLNRMSDYCSPCAYRPDHRTGDRSCPYTAGYWSFVHRHHERLVHNPRTAQAARGMERLKDLDEVLGQERERGDAAP

Crispr_ID: NZ_CP014485_12

• CRISPR_ID: NZ_CP014485_12
• CRISPR_location: 2619948-2620033
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_12

Consensus_repeat	Method
AGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP014485_12

>12.1|2619971|40|NZ_CP014485|CRISPRCasFinder
TCGGTGACCGACGGCTGAGGCATCACCTCAGCCCAATCCC

CRISPR arrays and Neighbor proteins around NZ_CP014485_12

CRISPR arrays

The CRISPR arrays of NZ_CP014485_12

>merge|NZ_CP014485|12|2619948-2620033|CRISPRCasFinder
AGCCCGGCCGGCGCTTGAGGCCATCGGTGACCGACGGCTGAGGCATCACCTCAGCCCAATCCCAGCCCGGCCGGCGCCTGAGGCCA

>NZ_CP014485|12|10|2619948-2620033|CRISPRCasFinder
AGCCCGGCCGGCGCTTGAGGCCA	TCGGTGACCGACGGCTGAGGCATCACCTCAGCCCAATCCC
AGCCCGGCCGGCGCCTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_018895301.1|2623023_2623956_-|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl|CDD|378959
NZ_CP014485.1|WP_061405481.1|2616124_2616562_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008417684.1|2613437_2613947_+|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|224929
NZ_CP014485.1|WP_061404327.1|2618759_2619809_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238874
NZ_CP014485.1|WP_010642955.1|2624557_2625352_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NZ_CP014485.1|WP_061404326.1|2615136_2615970_-|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224651
NZ_CP014485.1|WP_003950360.1|2626618_2627224_+|GrpB-family-protein	unknown	unknown	gnl|CDD|377252
NZ_CP014485.1|WP_008417686.1|2614003_2614378_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_031178257.1|2614420_2614960_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404328.1|2625453_2626437_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP014485.1|WP_003950374.1|2612589_2613399_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404329.1|2628834_2631360_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223650
NZ_CP014485.1|WP_003950365.1|2622619_2622931_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008417680.1|2612182_2612593_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_010642959.1|2627989_2628763_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NZ_CP014485.1|WP_003950363.1|2624281_2624548_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224393
NZ_CP014485.1|WP_003950367.1|2620194_2621415_+|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|181146
NZ_CP014485.1|WP_008417677.1|2610790_2611807_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP014485.1|WP_003950366.1|2621742_2622543_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003950369.1|2617212_2618610_-|cystathionine-beta-synthase	unknown	unknown	gnl|CDD|273464

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_018895301.1|2623023_2623956_-|Bax-inhibitor-1/YccA-family-protein	gnl|CDD|378959	pfam12811, BaxI_1, Bax inhibitor 1 like. The Bax-inhibitor-1 region of the receptor molecules is conserved from bacteria to humans.	1.24495e-84
NZ_CP014485.1|WP_008417684.1|2613437_2613947_+|roadblock/LC7-domain-containing-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	1.31302e-19
NZ_CP014485.1|WP_061404327.1|2618759_2619809_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238874	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it turn are loaded onto the acyl carrier protein FeeL. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	2.94117e-49
NZ_CP014485.1|WP_061404326.1|2615136_2615970_-|MurR/RpiR-family-transcriptional-regulator	gnl|CDD|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	2.67063e-36
NZ_CP014485.1|WP_003950360.1|2626618_2627224_+|GrpB-family-protein	gnl|CDD|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	7.93459e-63
NZ_CP014485.1|WP_061404328.1|2625453_2626437_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.38645e-87
NZ_CP014485.1|WP_010642955.1|2624557_2625352_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	3.90076e-14
NZ_CP014485.1|WP_061404329.1|2628834_2631360_+|ABC-transporter-permease	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	4.19677e-25
NZ_CP014485.1|WP_010642959.1|2627989_2628763_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	4.41039e-106
NZ_CP014485.1|WP_003950363.1|2624281_2624548_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	1.27369e-18
NZ_CP014485.1|WP_003950367.1|2620194_2621415_+|acetyl-CoA-C-acetyltransferase	gnl|CDD|181146	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase.	0
NZ_CP014485.1|WP_008417677.1|2610790_2611807_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	9.69952e-115
NZ_CP014485.1|WP_003950369.1|2617212_2618610_-|cystathionine-beta-synthase	gnl|CDD|273464	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase. Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family].	0

Protein sequences

>NZ_CP014485.1|WP_061404327.1|2618759_2619809_+|SGNH/GDSL-hydrolase-family-protein
MARRIAAGAAYGGGGIGLLGVAGVGVLLAEAQLAKRSVGSQGNGAAPPRADGVYGRAFGIRPDGEPPLEPLRFLMLGDSTAAGQGVHRSRQTPAALLASGLAAVAERPVELRNVAVPGARSDDLDRQVSLALADGGWVPDVCVLMVGANDVTHRMAATESVRLLASAVRRLRTAGAEVVVGTCPDLGTIEPVYQPLRWLARRASRQLAAAQTIGTVEQGGRTVSLGDLLGPEFAQNPRELFGPDNYHPSAEGYATAAMAVLPTLCASLGLWPEGERPEAARDEGFLPVARAAVRAASEGGTEVTAATGPRGPLALLKRRRRRRIPHEPSPNPAPQTPAPDRGGLNRRPG
>NZ_CP014485.1|WP_003950369.1|2617212_2618610_-|cystathionine-beta-synthase
MHIHDSMVDLVGNTPLVRLNNVTEGIQATVLAKVEYFNPGGSVKDRIALRMIEDAEERGLLGPGSTIVEPTSGNTGVGLAIVAQQKGYKCIFVCPDKVSLDKINVLRAYGAEVVVCPTAVDPEHPDSYYNVSDRLVRETPGAWKPDQYSNPNNPLSHYHSTGPELWEQTDGKITHFVAGIGTGGTISGTGRYLKEVSDGAVQVVGADPEGSVYSGGSGRPYLVEGVGEDFWPTAYDRNITDRIVAVSDKDSFQMTRRLAKEEGLLVGGSCGMAVVAALEVAREAGPDDVIVVLLPDSGRGYLSKIFSDEWMNDYGFLDQGGDEPRVGDVLRDKEGAMPSLVHMHPEETVGEAIEVLREYGVSQMPIVKPGAGHPDVMAAEVVGSVVERELLDALFASRAALDDPLEKHMSRPLPQVGSGEPVADLMAVLGKADAAIVLVEGKPTGVVSRQDLLSFLARSAGTAVE
>NZ_CP014485.1|WP_061405481.1|2616124_2616562_-|hypothetical-protein
MRKVGRAFFVLSVAAGMTVALQGSASAASYTYRATDVIGGPDWNQLKACSYVNYNGEAGRACFQPNGDKFWVQDLKADGHHVEMNAQVNVNGNWYHCLNYHGKAAGWTSCSFATVVPENARIAYNVSVWEGDKLLRSGQLIAADT
>NZ_CP014485.1|WP_061404326.1|2615136_2615970_-|MurR/RpiR-family-transcriptional-regulator
MTHSPAGRLQGLFEGRRLTPTQRRIAHCMVRHADEVPFLSSVELAELAGVSQPSVTRFAVALGFDGYPALRRDLRERAPGAPLAPAEANGYQQAVEAEVANLRRLADFLADPAPLQRAGRLLAQSRPLPVLGLRAAAAQARGFAYFAAKVHPDVRLLDEGGTMLVDRIDAARLAGASALLCFALPRHPREVVEALAYARERGLTVVTVADSAFAPVAAESDILVPGAVGTGLAFDTACAPMLLGRVLLEAMCDALPDAQARMERFDVRAADRGLFAD
>NZ_CP014485.1|WP_031178257.1|2614420_2614960_-|hypothetical-protein
MAVVQRAGAAPLWWLGVVAAGAGLVPEGLTGRRIGVLVGALLFLLAAAVVALVRGGRAAALAAEAERAARSDVLQARSVTVRNWRRGHRWWLLLAFAAALGSAFALPAAGGMALAGWGTGLWLRARGTGRVEEAREVLLWTAADALGRGAGDPLGARTTRLWTTGTEAGDAAPGGGRRR
>NZ_CP014485.1|WP_008417686.1|2614003_2614378_+|hypothetical-protein
MANTETSLKEAMSVIEGATGVALVDYTSGMALGTLGGGKDFNLEVAAAGNTDVVRAKLRTMEHLGLKEEIEDILITLSGQYHLIRLLKSRGGNGLFLYLVLDAGRANLAMARHQLRRIETELEV
>NZ_CP014485.1|WP_008417684.1|2613437_2613947_+|roadblock/LC7-domain-containing-protein
MAAEREVLDELQRLRARVPLLSGALAASADGLVLAQDTAGVEAESLAALTAAALGVAVRLTDATARGSFRELLVRGEKGYVATYAAGSSAVLTLLAEDRINVGRLHLEGRRAGTRIGALVDAALERAATPQPRPEHTRTAMPARPAAPPPQAPGPATGTPPGVLPRRPV
>NZ_CP014485.1|WP_003950374.1|2612589_2613399_+|hypothetical-protein
MRPPASPAPTAPLPAVSPMLRRLAEERATGALMRESGTLYLADGQVVHAESPATPGIDVLLTAGGTLARAGWWEAVAAAGARQRVAAYLVDSGRVPGGALELCHLGALYDAAFFALAPTSTPARFRYGVSHWIGPVHPVAAGSVERETLRRRALLDRIWPDATVDTAPLVRLPDAAAPPLTPRRRAVLAAVDGSRSAAEIARGLGRSAFHTLVDVRRLAAAGALDAVRSCGRPDDGSSGPRAGAPVLPEVTPDPDIALLRRLRDALEVL
>NZ_CP014485.1|WP_008417680.1|2612182_2612593_+|hypothetical-protein
MPGIDECLLDIMKLPGARGAAVVDWTSGLALGTIGESPHDDHEATAAETAEVARMAAEQPAFAQESARSGTPDEDPPASGVEDVIVTSPAGYHILRFVETDFDSSVFVHLWLHRSEGNLALARIRLGELARRLVLA
>NZ_CP014485.1|WP_008417677.1|2610790_2611807_+|LacI-family-DNA-binding-transcriptional-regulator
MGSRQRPTIKTVAARAGVGRTTVSRVINGSELVSDEARTAVLAAIAELNYVPNSVARGLVTSRTDSVALVIPESESRLGSEPYFSAVIRGVSTGLTERRIQLQLVLVRDQAERDQLTESVAERRVDGVLLVSVHEQDPLPGLLENMGLPTVLAGRRAHGEPLSHVRADNEGGAAAAVAHLVARGRRRIATISGPLDMDVSRSRLDGWRDALRDEGVEAAETLVATADFTEAGGEAAMRSLLERDPGLDAVFAASDVMAAGALAELRRQGRRVPEDVALIGFDDSVIARHSNPPLTSVRQPVEAIGRTMAQILLAEIDDPGQPRQHVVLPTELVVRESS
>NZ_CP014485.1|WP_003950367.1|2620194_2621415_+|acetyl-CoA-C-acetyltransferase
MPEAVIVSAARSPIGRAFKGSLKDVRPDDLTAHIIETALAKVPELNPRDIDDLMLGCGLPGGEQGNNLGRIIAVQMGMDHLPGCTVTRYCSSSLQTSRMALHAIKAGEGDVFISAGVETVSRFAKGNSDSLPDTRNPVFAEAEARTAAVAEQGADSWHDPREDGKLPDAYIAMGQTAENLARLKGVTREEMDEFGVRSQNLAEEAIKKGFWEREITPVTTPDGTVVSQDDGPRAGVTLEGVSGLKPVFRPDGRVTAGNCCPLNDGAAALVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGYGPVEASNQALRRAGLTIDDIDLAEINEAFAAQVIPSYRDLGLPLEKVNVNGGAIAVGHPFGMTGARITTTLINSLQFHDKQFGLETMCVGGGQGMAMVIERLS
>NZ_CP014485.1|WP_003950366.1|2621742_2622543_+|hypothetical-protein
MTLALLIALAAVVAVGAVALHAVHGLRRQIAALRAELHATHSGRATVPAARADADGIREAVAEALAEERERELAEARAFWAAQEARDASDAPSLLGGLHGLVDDLFIPRQADLAGLDALDAAEAAQHLPAAEPEEDSPELAAARRRHPSHPDFVPVRPTPVERETAGDDHETTVAVLEELAQARTALADVRPGPLGTLDVYVFADGTTLCMTPGHRETAELLAGSLRAGEAPVLLGGSGVSGAYALTFSCGEDNVYLLADRVIASV
>NZ_CP014485.1|WP_003950365.1|2622619_2622931_-|hypothetical-protein
MLDTTPLTSAVDQFADRLRAAPQSRLQRGAAAEALELARELSARAQRLEEPSGEVRVMPDAGMFAVADQVTVAAHDLALVLPGEAALESAVARVAEARERAGI
>NZ_CP014485.1|WP_018895301.1|2623023_2623956_-|Bax-inhibitor-1/YccA-family-protein
MRSSNPVFSRRGFSRDNGHAQFNAAPQAGGPAVGTQQGNPYAGGNPYAGQNPYAGQNPYAQGDQQTYANPYAQDQYGVQAPTTDRMTMDDVVMRTATTLGTLIVTAALAWWFLPVDAANMGKSYGIAIGAGLVAMVLALVQSFKRKASPALILAYAALEGVFLGVVSNVVDTHIASGAAMQAVIGTMAVFTAVLVAYKAGWIRVNRRFYGFVMAAAMGFVLLMAVNLLFAVFGGGDGLGFRSGGLGIIFGIIGVLLGACFLALDFKQVEDGIAYGAPREESWLAAFGLTMTLVWIYMEFLRLIAILQGDD
>NZ_CP014485.1|WP_003950363.1|2624281_2624548_-|helix-turn-helix-transcriptional-regulator
MTPRTEGAGSGAAAAPDPVHNRIAMLRVERQVTRRQLADALGVHYQTIGYLERGEYSPSLHLALRIAAYFEVPVEFIFSLTPFAPLKP
>NZ_CP014485.1|WP_010642955.1|2624557_2625352_-|ABC-transporter-permease
MNSLRTPTDVGYYVIGSAVFLFVILRNRDNIDETTGLSAGALMLPGVLAFSMIFAALFGLATAVATEREDGTLLRAKSLPHGTTGYVVGQSTRTALEVCFSLTLLLVPGLILLDDGWSGGVWGVPHAASLLVLGVLASTPLGFAVGSLVKNPRTLGGWGFLLMGGMVAISGTFFPLSVLPGWAAGLAQVFPLYWLGHGLRSAMLPDAAAAGEINGTWQVWESYAVLGAWALLGLVLAPVLLRRMARRESGASMSARKETALQRY
>NZ_CP014485.1|WP_061404328.1|2625453_2626437_-|ABC-transporter-ATP-binding-protein
MGEPEMAFDSGGTGGGGEVVVDVRDLWMRYGEKDVLRGVSFEIRRGEVLGLLGPNGAGKTTTIEIMEGFRQPSSGHVRVLGEDPLHGGDAWRARVGVVLQSWRDHSRWRVGALLEQFASYYRPYAGRDGYPGPYEVAELLARVGLSDKAGTKVGALSGGQRRRLDVAVGIVGRPRLLFLDEPTTGFDPKARSDFHDLVHALADLEDTTVLLTTHDLAEAEKLADRILILDGGRIVADGSAEQLARQVAGEDEVRWTRDGVREVHLTPDGTRFTRELFERYGAEITELEVRRASLEDTYLRMVARSEAGLEEPAPDQETVKERTGEPA
>NZ_CP014485.1|WP_003950360.1|2626618_2627224_+|GrpB-family-protein
MPDQQPPDRPEDRTPMTDTEIEAAYVTAPPRLNGPVTLAPYDPRWPEAYAALAARIGERLTPLPHRLDHAGSTSVPGLPAKPVLDLVLTVPDPADEDAYVPALAPLGLRLTIREPDWYAHRLLRGAAGHPAADAVNLHVFPEDCPETARMLRFRDHLRADAADRDLYARTKRELSARSWTYTQQYADAKSEVVAEILRRAG
>NZ_CP014485.1|WP_010642959.1|2627989_2628763_+|ABC-transporter-ATP-binding-protein
MTTTTPLASRSTEVAARATELSKVYGTDETRVVALDQVSIDFRQGELTAIMGPSGSGKSTLMHCVAGLDTFDGGSVRIGDTELGSLKDKQLTQLRRDKIGFIFQAFNLLPTLTALENITLPMDIAGRKPDQAWLDQVIDMVGLRDRLKHRPAQLSGGQQQRVAVARALASQPEIIFGDEPTGNLDSRSGAEVLGFLRNSVRTLHQTVVMVTHDAVAASYADRVVFLADGRIVDEMHRPTADSVLDRMKEFDAKGRTS
>NZ_CP014485.1|WP_061404329.1|2628834_2631360_+|ABC-transporter-permease
MFRTALRNVLAHKARLLMTVLAVMLGVAFVSGTLVFTDTLGNALRNQSAKSYDDVAVSVQTYADQRDQEKTGIDAATLEKIQGIDGVAAAHGRVSGFAGVADPDGKLIGSGWSNTGANFAPGADGKDPQYVFTDGKGPKAGQVALDRATADKGEYQVGDKVRVATNGPVQELTLSGVFTTEDGAVNAGGSLVLFDQRTAQKQYLRPGYFKDVTVTAASGTSDTALLEKVEALLPEDATAQTGQALAEEQAKDIESGLTGLNTMLLAFAGIALFVGVFLIANTFTMLIAQRTRELALMRAVGASRRQVKRSVLAEAALVGLVASAVGFGLGLGLAVALRSAMDAFGAEMPAGPLVVSPVAVGSAFGVGVVITVLAAWLPARRAAKIPPVAAMNSVHAVATVKSLVVRNTIGSIVTAAGAVAIVAGASKGGGDGRYLIAGGAFFALLGVMVLIPLLSRPVIAAVRPLLTKVFGVSGKLAAQNAVRNPRRTGTTASALAIGLTLVTGLSVLGLTVGQAIDRMTTDHIRADYMVTMASGRPMDSSALKALEGADGVSAVSPKQAAGFQFEDDYLGASSVTPGAVDKVFHLKVVDGSLATLEDGAIAVDTKTADKRGWKVGDTLPVTFDDEKKGELKVGATFEGNEFLDSVLIDRAVADAHEAAPMIMEIWVNTDGGPSDSARQALVDALGNNPAIDVMDQQEIRNAFGGIINTMLYIMYGLLAMALIIAVLGVVNTLAMSVFERQQEIGMLRAIGLDRRRVKRMIRLEAVVISLFGAVLGTALGVFLGWAIGETIAESVPGYELVLPWDRIAIFLALAGLVGVLAALWPARSAARLNMLTAIKTE

Crispr_ID: NZ_CP014485_13

• CRISPR_ID: NZ_CP014485_13
• CRISPR_location: 2974665-2974875
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014485_13

Consensus_repeat	Method
CGTGCCTGGTCACTGACTGGCCTCAATCGCCGGCCGGGCTGT	PILER-CR

spacers of NZ_CP014485_13

>13.1|2974709|54|NZ_CP014485|PILER-CR
CGCAGGGTCGAGACGGGCAGGTGGAGGCGGAGCCCAGCCACCACCCGCCCAATC
>13.2|2974807|38|NZ_CP014485|PILER-CR
CAACGACCGGCACCCCCAGACGCGGCGCAGCCACGCCC

CRISPR arrays and Neighbor proteins around NZ_CP014485_13

CRISPR arrays

The CRISPR arrays of NZ_CP014485_13

>merge|NZ_CP014485|13|2974665-2974875|PILER-CR
ACAGCCCGGCCGGCGATTGAGGCCATCAGTGACCCGCAGGGTCGAGACGGGCAGGTGGAGGCGGAGCCCAGCCACCACCCGCCCAATCACAGCCCGGCCGGCGATTGAGGCCAGTCAGTGACCGGGCACGGGCAACGACCGGCACCCCCAGACGCGGCGCAGCCACGCCCCAGCCCGGCCGACGATTGAGGCCAGTCGGGGACCAGGCACG

>NZ_CP014485|13|3|2974665-2974875|PILER-CR
ACAGCCCGGCCGGCGATTGAGGCCATCAGTGACCCGCAGGGTCG	AGACGGGCAGGTGGAGGCGGAGCCCAGCCACCACCCGCCCAATCACAGCCCGGC
CGGCGATTGAGGCCAGTCAGTGACCGGGCACGGGCAACGACCGG	CACCCCCAGACGCGGCGCAGCCACGCCCCAGCCCGGCC
GACGATTGAGGCCAGTCGGGGACCAGGCACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_008404110.1|2962417_2963413_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381313
NZ_CP014485.1|WP_008404117.1|2966381_2966645_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008404125.1|2971499_2972360_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404441.1|2972705_2973965_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP014485.1|WP_061404442.1|2974950_2978169_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_018469941.1|2983249_2984146_+|1,4-dihydroxy-6-naphthoate-synthase	unknown	unknown	gnl|CDD|270353
NZ_CP014485.1|WP_010643321.1|2968521_2968788_+|DUF2530-domain-containing-protein	unknown	unknown	gnl|CDD|378488
NZ_CP014485.1|WP_015507349.1|2982456_2983182_+|futalosine-hydrolase	unknown	unknown	gnl|CDD|236194
NZ_CP014485.1|WP_061404443.1|2980424_2981882_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP014485.1|WP_003950020.1|2984787_2985039_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003950034.1|2965745_2966183_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP014485.1|WP_003950032.1|2966718_2968164_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_CP014485.1|WP_061404444.1|2986519_2988451_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP014485.1|WP_003950021.1|2984262_2984646_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP014485.1|WP_061404439.1|2963632_2964223_-|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl|CDD|274058
NZ_CP014485.1|WP_008406155.1|2979152_2980013_-|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NZ_CP014485.1|WP_008415563.1|2981911_2982436_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_010643339.1|2985347_2986058_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014485.1|WP_061404440.1|2968956_2971395_+|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319795
NZ_CP014485.1|WP_008404115.1|2964301_2965648_-|MFS-transporter	unknown	unknown	gnl|CDD|340863

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008404110.1|2962417_2963413_+|aldo/keto-reductase	gnl|CDD|381313	cd19087, AKR_AKR12A1_B1_C1, AKR12A, AKR12B, AKR12C families of aldo-keto reductase (AKR). Streptomyces fradiae TylCII, Saccharopolyspora erythraea EryBII, and Streptomyces avermitilis aveBVIII are founding members of aldo-keto reductase family 12 member A1 (AKR12A1), B1 (AKR12B1), and C1(AKR12C1), respectively. TylCII acts as a NDP-hexose 2,3-enoyl reductase. EryBII is a mycarose/desosamine reductase involved in L-mycarose and D-desosamine production. aveBVIII functions as a dTDP-4-keto-6-deoxy-L-hexose-2,3-reductase.	3.9928e-167
NZ_CP014485.1|WP_008404115.1|2964301_2965648_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.19265e-82
NZ_CP014485.1|WP_061404441.1|2972705_2973965_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	3.70281e-71
NZ_CP014485.1|WP_018469941.1|2983249_2984146_+|1,4-dihydroxy-6-naphthoate-synthase	gnl|CDD|270353	cd13635, PBP2_Ttha1568_Mqnd, A menaquinone biosynthetic enzyme exhibits the type 2 periplasmic-binding protein fold. This group includes Ttha1568 (MqnD) from Thermus thermophilies HB8, an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. Ttha1568 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.15302e-142
NZ_CP014485.1|WP_010643321.1|2968521_2968788_+|DUF2530-domain-containing-protein	gnl|CDD|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	0.00969272
NZ_CP014485.1|WP_015507349.1|2982456_2983182_+|futalosine-hydrolase	gnl|CDD|236194	PRK08236, PRK08236, hypothetical protein; Provisional.	6.12362e-66
NZ_CP014485.1|WP_061404443.1|2980424_2981882_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.60991e-27
NZ_CP014485.1|WP_003950034.1|2965745_2966183_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.04287e-20
NZ_CP014485.1|WP_003950032.1|2966718_2968164_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.89915e-107
NZ_CP014485.1|WP_061404444.1|2986519_2988451_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.91576e-47
NZ_CP014485.1|WP_003950021.1|2984262_2984646_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	5.07314e-27
NZ_CP014485.1|WP_061404439.1|2963632_2964223_-|RNA-2',3'-cyclic-phosphodiesterase	gnl|CDD|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	2.38125e-35
NZ_CP014485.1|WP_008406155.1|2979152_2980013_-|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	2.60749e-109
NZ_CP014485.1|WP_010643339.1|2985347_2986058_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.84901e-26
NZ_CP014485.1|WP_061404440.1|2968956_2971395_+|HAD-IC-family-P-type-ATPase	gnl|CDD|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0

Protein sequences

>NZ_CP014485.1|WP_061404441.1|2972705_2973965_+|cytochrome-P450
MPSSAPPEQEPLVLDPTGADLHAEHRALHARGPATRVDVLGVPAWSVSDPVLLRALLTSPDVSKDGRAHWPAFAETVQSWPLALWVAVRNMFTSYGADHRRLRRIIAPAFSARRVAAVRPVVERITAGLLDDLAALPPDAPVDLREKLAYPLPVAVIGHLMGVPEERYAHFRAVVDGVFDTTLGREEAAANTGALYVVLDQLIATRRAEPGDNLTSLLLATPDEEGAEPALSHEELRDTLLLVISAGYETTVNVIDQAVHALLTVDGQLDLVRSGQVGWGDVVEETLRHESAVKHLPLRYAVRDIPLPDGRTIARGEAILSSYAAANRHPRWHDDADVFDAGRLSKEHLAFGHGVHFCVGAPLARLEVEVCLRLLFARFPGLALDLPAEGLPPFPSLISNGHRNLPVWLHGGALGEGPG
>NZ_CP014485.1|WP_008404125.1|2971499_2972360_-|hypothetical-protein
MRIRATVAVVSGALALSALTGAAAQAAPGPDRERIQVPTAESVFGKQATAKGKGFKAAAVPKISKVTVNGGKDIVLGTTKAKTFSVSITASHASNIGDAYAYFWHGSTYETADGVFIPNEEYASCKASSATTSTCKLTFTVDPQWELINDLAGSWNVGVGALAADDSDFAWNDKHSKTRVQRYSKLVVNATPEPVKKGKTLTVNGTLSRANWDTWKYAGYTQQSVKLQFKKKGAASYTTVKTVKSGSKGALKTTVKAASDGYWRWSFAGTSTTPAINSTADFVDVK
>NZ_CP014485.1|WP_061404440.1|2968956_2971395_+|HAD-IC-family-P-type-ATPase
MTQRGQVDTGGSDSGNSRIDTGAEPDAAPPAVPPEPGLSSAEVAEAVARGEVNDVPVRSSRSLAEIARANIFTRFNAIIGVLWVIMLFVAPIQDSLFGFVIVANTGIGIFQEWRAKRTLDGLAVIGEAKPTVRRDGRPGEVSTSEIVLGDLIEIGPGDKIVVDGEVREADGLEVDESLLTGEADPVVKRPGDEVMSGSFVTAGGGAFRATKVGREAYAAQLAEEASRFTLVHSELRSGISTILKYVTWMMVPTAIGLVVSQLVVRDNDFKNAVARTVGGIVPMVPEGLVLLTSVAFAIGVIRLGRKQCLVQELPAIEGLARVDTVCLDKTGTLTEGGMDVQAIRPLGGADEAYVRRVLGALGAGDPRPNASLQAVIDACPAPEGWRTTGTLPFSSARKYSGASLDEGDATHRTWLLGAPDVLLRPGAEALAETDALNERGLRVLLLSRAAGGLDGPDPGAGAEPTALVVLEQRLRPDAADTLRYFEDQHVAAKVISGDNAVSVGAVAGKLGLPGAERTYDARKLPKEPEALADTLDENTVFGRVTPQQKRDMVGALQAHGHTVAMTGDGVNDVLALKDADIGVSMGSGSEATRAVAQIVLLNNSFSTLPSVVAEGRRVIGNITRVATLFLVKTVYSVLLAILVVLSQTEYPFLPRHLTLLSTLTIGVPAFFLALAPNKERAQPHFVKRVMRYAIPGGVIAALATFTTYMTARAYYTGPDSLPAETSAATLTLFLVSLWVLAIIARPYTWWRVGLVATMAGAFLVVLAVPWLQDFFALRLVGSVMPWAAVGIAVIAAALIEVVWRLVDRRLPV
>NZ_CP014485.1|WP_010643321.1|2968521_2968788_+|DUF2530-domain-containing-protein
MKKWTPRHEAPEPLEGPVVATITGGTILWFVLFLAQLPFYGWYADHGHTWWIWTCLAGAGLGCLGVWYVRRREAALKRAAAAAPQPGS
>NZ_CP014485.1|WP_003950032.1|2966718_2968164_-|NCS2-family-permease
MPTSAPAQDATSEQPNPPSGALDRYFKITERGSTLSREVRGGFATFFAMAYIIVLNPIILGSAKDMYGHQLDNGQLVTATVLTAALTTLLMGVIGNVPVALAAGLGVNTVVALQLAPRMSWPDAMGMVVLAGFVVMLLVATGLRERVMSAVPLGLRKGIAIGIGLFIMLIGLVDAGFVSRIPDAAQTTVPLQLGADGHLNGWTVLVFVLGVLLTLALMVRKVPGAILISIVAMTVLALIINAVADIPSWGLTTPEWPGNPVATPDFGLIGQVSLFGGFAKVGLLTGILFVFTVLLSCFFDAMGTIMAVGDEAELTDAQGNMPGINKVLFVDGIAVAAGGASSSSATTCFVESTAGVGEGARTGFANIVTGGLFAIGLFLTPVVTMVPSQAATPALVAVGFLILSGSIGAIDWTDFTIAIPAFITFMMMPFTYSITNGIGMGFISFCVLRLAAGRGRSVPAAMYVVSGVFAFYYLMPALGLT
>NZ_CP014485.1|WP_008404117.1|2966381_2966645_+|hypothetical-protein
MDTHVLSLRMDSELFERLRGHAARRGMSVQDYVVRTMIRDDFDQRFQTAVEETEKFYGDEDGGAPGAGEVAEEPARDGAVNGAARPT
>NZ_CP014485.1|WP_003950034.1|2965745_2966183_-|MarR-family-transcriptional-regulator
MPDLTHGEDADAVNALRSSVMRLSRRLKHQRVDESLSPTEMSVLGTLARCGTATPGELARKEHVQPPSMTRIVALLEAKGLVRLEPHPEDRRQKVVTQTEEAEAMLEESRSKRNAWLASLAAELDEEEWAKVRAAAPVLEKLAHL
>NZ_CP014485.1|WP_008404115.1|2964301_2965648_-|MFS-transporter
MSTGPGADSAPAPAAHDSTPPAPKQSMFSSLKIHNYRLFFTGQVISNTGTWMQRIAQDWLVLTLTGSSAAVGVTTALQFLPMLLFGLYGGVLVDRLPKRPLLLFTQSAMGLTGLALAALTLTGHVQVWHVYVTAFVLGLVTVVDNPARQTFVSEMVGPRQLANAVSLNSANFQSARLVGPAVAAVLISAVGSGYAFLINGLSFAAPIAGLLMMRMGDLHKAPRTPRGKGQLREGLRYVAGRPDLIWPIVLVGFIGTFGFNFPIWLSAFADKVFDGGPGMYGTLNTLIAAGSLAGALLAARRGAGRLRLLVAAAAAFGVLEIVAAFAPSVWIFAVLMVLTGMFGLTVNVTANSYVQMATEPQMRGRVMALFMMVFTGGTPLGAPLLGWITDEYGARTGFAVGGAISLLAALAVGLILARVGGLKVKVDLRRGRKHIRFVPDEKRLAPAA
>NZ_CP014485.1|WP_061404439.1|2963632_2964223_-|RNA-2',3'-cyclic-phosphodiesterase
MASPAPRPRLFVAVVPPDAVLAELRRATAALDALPGAGRLRPTEAGGRHVTLAFLGACDPGRLDGLAARLARAAHRTAPFPLALRGAGHFGDRVLWARPDGDLDALARLADRVRAAATRAGLPPDAEHAFRPHLTLARVRPGPPLRLAPFAEALAQLAAGPWQADEVRLLRSVPPPGGVPGARPAYATEGRWPFGG
>NZ_CP014485.1|WP_008404110.1|2962417_2963413_+|aldo/keto-reductase
MKYTQLGRTGLKVSRLVLGTMNFGPKTGEAESHALMDTALDDGINFFDTANVYGWGENKGRTEEILGTWFAQGGDRRDKVVLATKVYGNMGADGAAWPNHDRLSALNIRRAVDASLRRLQTDHIDLYQFHHVDRRTPFDEIWQAMDTLVQQGKILYAGSSNFPGYKIAQANEAAARRGSLGLVSEQCLYNLAERRAEMEVIPAAEEYGLGVIAWSPLHGGLLGGAIRKEREGGGSRTNDGRSGDALANSTIRAQVQAYEDLLEKHGLEPGEVALAWLLTRPGLTGPIVGPRTDEQLASAVRAVELELPQELLTALDEIFPGPGPSPEAFAW
>NZ_CP014485.1|WP_061404442.1|2974950_2978169_-|hypothetical-protein
MTHPTPAQEGKDPFGTARRRRTVLDSWAASPARFREDANAEEDLALGGYRDRLIVELAQNAADAASRAGTDGRLRLTLHESAGTHVLAAANTGAPLDATGVESLSTLRASAKRPATGTATGAAPGAGPSVGRFGVGFAAVLAVSDEPAVLSRTGGVRWDLAQAREAAREVARHSPGLGDELIRRDDHVPLLRLPFPAEGIPPEGYDTVVVLPLRDAAAQDLAERLLAGVDDALLLALPGLTEIVVETPESTRVLRRRDEEPYVVIEESTGGSGATGAPAETRRWRTATSGGPLDAPLLADRPVEERLRPYWSVVWAVPVDAEGAPVRPATAPVVHAPTPSDEPLGVPALLIASFPLDTARRHVAPGPLTDFLVARAAEAYAGLLGAWRPVGPAAVGLVPGPLGQAAVDGAVRAAVLDLLPRTAFLPPALPPAGPDEEPDTDVPLLRADRPEALRPIEAELVEGAGEATVRVLAEVLPTLLPAGLERRAELRTLGVGRLSLGEAIDRLAGVERSPAWWYRLYDSLAGVDPDRLQGLPVPLAAGSTAGSPRQVLLPGPAEDGPRPAALARLGLKVAHPEAAHPLLEKLGALPATPRAVLRTPQVRAAVAESLEGDGYALRDDAPDAEELAELVLTLARDAELAPGDEPWLGALALPDEDGELSPAGELVLPGGEFASIMREGELAAVDEEWAERWGEQPLAACGVLARFTLVRATDVALDPDELEPRDTDFAEPDDVGLLDAVDVWCEDVLDQLPDGPVPPVATEITAVRDLDLVDDDRWPEALALLSRPPLRDALTQPVRVLLPDGTTESVRPYTAWWLRGHPVLDGRRPAGLRAASGDPLLAGLYDEVDAAGFDDALVLRALGVRTTAAALLDEPGGAAELLDRLADPDREVSARQLHALYGLLAELDPEEVTLPDELRAVADGVVTVVDARDALVADAPDLLPFAAGRPLLPVAPALAARLAELLQVGRLSEAVRVTPAGEGVEYPVPEAVRELLGDGVPASYREHDELLADGVELDWHLTASGVLHAATLEGVAAGLAWGAGQWPRRFEVAALLEDPSRRAELSRDRWFD
>NZ_CP014485.1|WP_008406155.1|2979152_2980013_-|DUF3027-domain-containing-protein
MSAATTRSRTPDRLCAEAVDLARSVAEETAAPGVVGEHLAVTADGDRVATHYFACHDPGYRGWRWAVTVARASRAKYVTVDESVLLPGPDALLAPEWVPWSERLRPGDLGPGDLLPTEADDLRLEPGWIADEEPPPNSAVSADMAELVEAEDASLSAGPPADLPLAPERGSVASVAEELGLRRSRVLSRYGLLDAAERWEAQFGAESAMAQAAPAPCVSCGFLLPLAGSLRQAFGICANAYSPADGHVVSLAYGCGGHSEAAVMPTPPRPPDPALDETRLDPLPLD
>NZ_CP014485.1|WP_061404443.1|2980424_2981882_+|MFS-transporter
MRRAARVVGRALRTPVTGPARGIRKVTHAQGAGESGLGRLIELHGVNGAGDVMITVALASTVFFSVPTDEARGRVALYLAVTMLPFTLLAPVVGPLLDRLPHGRRAAMAGSMLARAVLALVLSGAVATGSLEMYPAALGVLVASKAYGVVRSAVVPRLLPQGFSLVKANSRVTLGGLLATGVAAPVGAGLQMIGPGWPLYGACLLFLGGAFLSFRLPPKVDSARGERRALLAADEQHLAAAVDARWDPVTTDDKTDDKTDSTDNKEEEKDRDGERGKGKEKERRRKGPGLRTVGPAVTHALAANACVRCQSGFLIFFLAFLLREHPLTGQSAAVSLAVVGVAAGAGNALGTAVGAWLRARAPEVIIVTVVGALVAVAVSAAVFFGAAVVAVLGAVAGFTQALAKLSLDALIQRDVPELVRTSAFARSETLLQMAWVVGGAIGIALPLRGPLGLSVGALIVALGWLTTVRALLASARRGASHPRVA
>NZ_CP014485.1|WP_008415563.1|2981911_2982436_+|hypothetical-protein
MTSLPRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVATVTIGSDSVNSEATCWNGGSKIDEKKLQQCLQDKGEGDSGDGAEVKTVKVDTEADVHIGVDPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSATGLWSFKLEKES
>NZ_CP014485.1|WP_015507349.1|2982456_2983182_+|futalosine-hydrolase
MRLLVATAVPPERDAVARAFGAPDTPEETALPGAVLLRTPGADVLAAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVVADRILAADLGAETPDGFVPVTGLGFGTDAHVPPAALVEAAREAGLVPGAVLTVSTVTGSADRTAELLARHPSAVAEAMEGFGVAEAAAAHGVPVLEIRAISNAIGPRDRDAWRIPAALTALTSAFVRLAPAEAGSPFALARARLVP
>NZ_CP014485.1|WP_018469941.1|2983249_2984146_+|1,4-dihydroxy-6-naphthoate-synthase
MSESGTGGGVQGTADEAGRLSIAYSPCPNDTFVFDAVAHGRVPGAPALDVTFADIDLTNGMAERGAYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLTREASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKVDAGLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGAERLTALAQALRTSVRMAWDDPAASRPYVLAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTRAAAEGLVPPLAPDALRFP
>NZ_CP014485.1|WP_003950021.1|2984262_2984646_-|cold-shock-protein
MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQRVEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGRYPDRASGAKVAGMLRAVADQLDV
>NZ_CP014485.1|WP_003950020.1|2984787_2985039_+|hypothetical-protein
MSDTTQQTPAPGDRLVKTGGIVFIIGALATLVTVAPLFLGSDPFPTAAYLVSMLMGVGFLIAGAGLVRQIAAQRRETRAAVEG
>NZ_CP014485.1|WP_010643339.1|2985347_2986058_+|response-regulator-transcription-factor
MIHSSGVLRSALVALLERERFQVTSASGFSRASSGTTGAPGTPGAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAGAGAERAGIGLAGASRGRAALVVLAGAEHPGVLRLAYAAGALGLVDRDGPANHLATAIRLAAGGGRYVDDGLAMSLLRAMDMPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRAAGWV
>NZ_CP014485.1|WP_061404444.1|2986519_2988451_-|ABC-transporter-ATP-binding-protein
MTRPRHTDGAPSPLLRPALTFARRRKGPLGALGAWSLLESARTFLTGYAVARALDDGFLAGDVRTGLLWLLALAAAALAGGFADAGVFRALGGVIEPLRDSLVRRVVRATLTRAVASPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSAGAFTGLAALSPRLLPLVLIPLTAGLALFAATLRPMAARQRDLLDADEHLAAFAGRTDHAARDIAATGAAPLVTAEAAPLITAEATAASALARWSAVRVTALGLAAHLPVATLLLAAPTLLSTGLTPGELLAALTYVTTALLPAVNALLTALGAAGSRLLVVLHRLLGEEADAADVREEQAHALRVDDGPRAPGACSQGKADDEVPAIPAPSLPREPVHGPEPFRAEPSPPGPRPTRGPRPTRPALPAVTLRGLTFAYGPDAAPVLDHLDLTVEPGEHLLVVGPSGAGKSTLLALLAGTAHPRHGQIHLAGHTARHARTLGTAARVLVPQEPYIFEATLHDNLTYLAPNAPAPRITEAIHTFTLTPLAADPARPLRPDHLTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAFASHPATVITVSHHFPAPEPGQRVLLLDGATPYLGTHASLLRESALYGELAAGLGEPSAAGSRGTAST

Crispr_ID: NZ_CP014485_14

• CRISPR_ID: NZ_CP014485_14
• CRISPR_location: 2998381-2998570
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014485_14

Consensus_repeat	Method
CGCCCGGCCAAAGAATGGCCTCAAACGCCGGCCGGGCTGTAGG	PILER-CR

spacers of NZ_CP014485_14

>14.1|2998427|56|NZ_CP014485|PILER-CR
GGATGCGGTGTGGCTGGGCTCCGCCCCTGCGTACCCGCCGTGACCCTGCGGGTCAC
>14.2|2998529|20|NZ_CP014485|PILER-CR
TTGCCGGGCTCCGTCTCGAC

CRISPR arrays and Neighbor proteins around NZ_CP014485_14

CRISPR arrays

The CRISPR arrays of NZ_CP014485_14

>merge|NZ_CP014485|14|2998381-2998570|PILER-CR
CGCCCGGCCCTCGATTGGCCTCAATCGCCGGCCGGGCTGGGATGCGGTGTGGCTGGGCTCCGCCCCTGCGTACCCGCCGTGACCCTGCGGGTCACCGATGGCCTCAAGCGCCGGCCGGGCTGTCGGTTGCCGGGCTCCGTCTCGACCGCCCCGGTCAAAGACTGGCCTCAAACGCCGGCCGGGCTGTAGG

>NZ_CP014485|14|4|2998381-2998570|PILER-CR
CGCCCGGCCCTCGATTGGCCTCAATCGCCGGCCGGGCTGGGATGCG	GTGTGGCTGGGCTCCGCCCCTGCGTACCCGCCGTGACCCTGCGGGTCACCGATGGC
CTCAAGCGCCGGCCGGGCTGTCGGTTGCCGGGCTCCGTCTCGACCG	CCCCGGTCAAAGACTGGCCT
CAAACGCCGGCCGGGCTGTAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003950004.1|3005215_3005617_-|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|367422
NZ_CP014485.1|WP_059214161.1|2990722_2993302_-|class-III-lanthionine-synthetase-LanKC	unknown	unknown	gnl|CDD|271199
NZ_CP014485.1|WP_061404447.1|2995344_2996442_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl|CDD|227119
NZ_CP014485.1|WP_037629850.1|3000990_3002700_+|acyl-CoA-oxidase	unknown	unknown	gnl|CDD|173839
NZ_CP014485.1|WP_030310290.1|3011614_3012154_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_059214163.1|2999559_3000624_+|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|377085
NZ_CP014485.1|WP_003950014.1|2993519_2994497_-|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238566
NZ_CP014485.1|WP_008415589.1|2996438_2997503_-|iron-ABC-transporter-permease	unknown	unknown	gnl|CDD|376439
NZ_CP014485.1|WP_061404445.1|2988447_2990343_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP014485.1|WP_008406866.1|3004261_3004870_-|ATP/GTP-binding-protein	unknown	unknown	gnl|CDD|225138
NZ_CP014485.1|WP_061404446.1|2994493_2995348_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224045
NZ_CP014485.1|WP_003950005.1|3004844_3005219_-|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NZ_CP014485.1|WP_061404444.1|2986519_2988451_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP014485.1|WP_061404449.1|3007156_3008227_-|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NZ_CP014485.1|WP_018471168.1|3002811_3004128_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP014485.1|WP_061404448.1|2997635_2998322_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223620
NZ_CP014485.1|WP_008415578.1|2990501_2990633_-|SapB/AmfS-family-lanthipeptide	unknown	unknown	gnl|CDD|380211
NZ_CP014485.1|WP_010643339.1|2985347_2986058_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014485.1|WP_010643360.1|3005613_3006636_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|340391
NZ_CP014485.1|WP_008406841.1|3011342_3011603_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003950004.1|3005215_3005617_-|roadblock/LC7-domain-containing-protein	gnl|CDD|367422	pfam03259, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	2.92122e-15
NZ_CP014485.1|WP_059214161.1|2990722_2993302_-|class-III-lanthionine-synthetase-LanKC	gnl|CDD|271199	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.	3.10991e-93
NZ_CP014485.1|WP_061404447.1|2995344_2996442_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl|CDD|227119	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism].	1.15589e-71
NZ_CP014485.1|WP_037629850.1|3000990_3002700_+|acyl-CoA-oxidase	gnl|CDD|173839	cd01150, AXO, Peroxisomal acyl-CoA oxidase. Peroxisomal acyl-CoA oxidases (AXO) catalyze the first set in the peroxisomal fatty acid beta-oxidation, the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. In a second oxidative half-reaction, the reduced FAD is reoxidized by molecular oxygen. AXO is generally a homodimer, but it has been reported to form a different type of oligomer in yeast. There are several subtypes of AXO's, based on substrate specificity. Palmitoyl-CoA oxidase acts on straight-chain fatty acids and prostanoids; whereas, the closely related Trihydroxycoprostanoly-CoA oxidase has the greatest activity for 2-methyl branched side chains of bile precursors. Pristanoyl-CoA oxidase, acts on 2-methyl branched fatty acids. AXO has an additional domain, C-terminal to the region with similarity to acyl-CoA dehydrogenases, which is included in this alignment.	3.16699e-50
NZ_CP014485.1|WP_059214163.1|2999559_3000624_+|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	7.40182e-50
NZ_CP014485.1|WP_003950014.1|2993519_2994497_-|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl|CDD|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	3.55483e-73
NZ_CP014485.1|WP_008415589.1|2996438_2997503_-|iron-ABC-transporter-permease	gnl|CDD|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	8.13833e-83
NZ_CP014485.1|WP_061404445.1|2988447_2990343_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.16748e-82
NZ_CP014485.1|WP_008406866.1|3004261_3004870_-|ATP/GTP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	1.44526e-35
NZ_CP014485.1|WP_061404446.1|2994493_2995348_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	4.48447e-133
NZ_CP014485.1|WP_003950005.1|3004844_3005219_-|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	9.79786e-23
NZ_CP014485.1|WP_061404444.1|2986519_2988451_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.91576e-47
NZ_CP014485.1|WP_061404449.1|3007156_3008227_-|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	1.56452e-05
NZ_CP014485.1|WP_018471168.1|3002811_3004128_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.9149e-39
NZ_CP014485.1|WP_061404448.1|2997635_2998322_+|HAD-family-hydrolase	gnl|CDD|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	5.11261e-24
NZ_CP014485.1|WP_008415578.1|2990501_2990633_-|SapB/AmfS-family-lanthipeptide	gnl|CDD|380211	NF033212, SapB_AmfS_lanti, SapB/AmfS family lantipeptide. Members of this family are class III lantipeptide precursors. These typically are short peptides, encoded next to the gene for the lantipeptide synthetase that creates the characteristic lanthionine (or beta-methyl lanthionine) bridges for which these natural products are named. Members of this family include SapB and AmfS, which are considered morphogens rather than antibiotics. Members also include labionin-containing peptides such labyrinthopeptins A1 and A2.	5.06968e-12
NZ_CP014485.1|WP_010643339.1|2985347_2986058_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.84901e-26
NZ_CP014485.1|WP_010643360.1|3005613_3006636_-|sensor-histidine-kinase	gnl|CDD|340391	cd00075, HATPase, Histidine kinase-like ATPase domain. This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.	2.79502e-14

Protein sequences

>NZ_CP014485.1|WP_061404448.1|2997635_2998322_+|HAD-family-hydrolase
MPEHLTSAAAPAPSDPAVPAARPVPGGAGPVVGFDLDMTLIDSRPGIGAAYRVLAAETGVLIDVDLVVSRLGPPLETELACWFPAEQVPAAAARYREVYPTTAIAPSLALPGAAQALEAVRAHGGRSLVVTAKNEEHARLHLDHLGLRADLVVGSLWAEAKGGALRAQGATVYVGDHVGDVRGARAAGAFSVAVATGGCTPDELRTAGADLVLPDLTAFPAWLAEFAR
>NZ_CP014485.1|WP_008415589.1|2996438_2997503_-|iron-ABC-transporter-permease
MPPAPPAAPSPAKAPPTAPRPRRDSAVRRAAWTVAALVALLVAVVLSLAVGARTVAPGTVVEALFQGATGPDAEVVREMRLPRTLIGVMVGAALAVAGTALQGITRNPIADPGILGISQGASVGVVLAIAFAGVHTLAGYVWFAFVGAGLAAVAVYAVAAGGRGGATPVKLALSGAAINALLVSVTTAVLTTSSSALDEFRFWNVGALQGRGADVAVQVWPFLLVGLALVASSARGLDALALGEDVAKGLGQRVAAVRITAGAGAAVLTGVGVAAAGPVAFVGLAVPHLVRHLVGGDHRWVLPLAALTGPVMLLASDTVGRVLFPPGEVPAGVMTALIGVPFLVALVRSRAVTA
>NZ_CP014485.1|WP_061404447.1|2995344_2996442_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MSGGSVVLKAGPEPARVRPAGYVPVRVGPASLLVPVRAVATGAVLAGVLAVVCVAYLSVGESFVAPGSVVDVLLGRPSPDTLVVGELRLPRMVAGLYVGAAFGIAGALIQTVARNPLASPDLIGVSQGASAATVAALIFGVTSYTVLPWISVGGGLLAALLVYLFAWRGGLQATRFVLVGVGFAVALRALTTLFLTKGDQTVAQQAQVWMSGSLNGRAWPEAALVGWTLLAALPALVWAARAQRTVTLDDATATSLGARLGRARLGLVLVGVVLASVATGAAGPVDFVALLAPQIARRLARTAQIPLVCSALAGAVTVVAADLLARRLFAPTELPVGVLTAAVGAPYLIWLLVTRHGPRATGGTS
>NZ_CP014485.1|WP_061404446.1|2994493_2995348_-|ABC-transporter-ATP-binding-protein
MTRPAARLTARDLTLAYEDRTVVPGLDLDIPDGRVTVIIGPNACGKSTTLRALGRLLRPVGGAVLLDGAELARLPTRQIARQIGLLPQTPVAPEAITVADLVARGRQPHQRWWQQWSEEDERAVTEAMARTATTDLADRPVDALSGGQRQRVWIAMALAQETGLLLLDEPTTYLDLAHQVEVLDLVRRLNREQGRTVVLVLHDLNQAARYADHLIAFREGRVVAEGAPAEVVTAGLVREIFGLECVVVPDPVTGSPLVVPGAPWDARPAPEPAVPTREESRATP
>NZ_CP014485.1|WP_003950014.1|2993519_2994497_-|iron-siderophore-ABC-transporter-substrate-binding-protein
MTRRTARPLLAATGALALAVTLTACGSGEETAADAGKDAGATRTVETAMGEVEVPEAPKRVVVLDTAELDSALTLGVKPVGAVRSDAAGGFASYLPEKELAGIENVGVIAQPNLEAIAALKPDLILTSKVRDEARYAQLSKIAATVMTENTGYPWKENFQVHAEALGKQKEADRATAAYEKRTAEVTEAVGGPAEAEKTEVNVVRFVEGADIRIYGRKNYIGTLLADVGLGRPAITDKATDGFSYDVSPEKIDLADADVVFTATYGDPEKAKETQTTSSALWRSLDAVKSGAVHKVEDELWIQGIGYTAAQQILDELEEALTSAS
>NZ_CP014485.1|WP_059214161.1|2990722_2993302_-|class-III-lanthionine-synthetase-LanKC
MNPEYALYSGTDRWFYDTPRRAGRAADGSGNGSDGHRYALARRPAPEGWESAERGDWFSLAPAGRQLPAQGWKIHVSATPDNAEEVLETVAGICQERATAFKFLAGPALLLHRNTKYADRAGSGKFVTVYPATTAACGELAAELADALKGSAGPVVLSDLRWGEGPVHVRYGAFAPRFTRAADGSLVPAVADPAGRLVPDTRGPAFRLPDWVELPDFLRPHAEARAAQGTTDLPYTVERALHFSNGGGVYAGSHRETGEAVVLKEGRPHAGLAADGADAVTRLQREYAALRALEGLACVPRVHGLHTVGEHRFLAMEFIPGTPLNTVFARRFPLSAAEPAAEALAEHTAWALRTHQLVTEAVEALHARGIAFGDLHMNNIMVAPDQLSVTLLDFEAATPAAERRPQIVANPAFVAPPHLRGTEVDRYALACLRLALFVPLTTLLPLDRDKAAHLAGLAADRYGIDRALFDEAVTELAGPARPEAGPSRGRPPVSATDWPAARDSMVAALLASATPGRDDRYFPGDIAQFATPAGGQSYGYGAAGVLHALHTVGARCEEAEEWLIRTTRRPASGTPTGFYDGLTGIAWTLDRLGHREEALRLAHLVAAEPLDALGPGLHSGAPGVALALRDLADATDDPALGQAADRAEAAALRPAAPGGKAGLLHGPAGTALLCLRRHARTGEPALLDTAATALREELGRCVPGPDGSLVVSEARRTMPYLGSGSAGIAMVLDDYLAHRPDPAFEEARTALLRATGSAFYIQPGLFRGVAGLLLHLARTTTPGDRAARTALLTRQTALLDWHALTYQGHLAHPGEQLTRLSMDLSTGTAGVLLALAATHGEPAAHLPFLPPLRRPTDRP
>NZ_CP014485.1|WP_008415578.1|2990501_2990633_-|SapB/AmfS-family-lanthipeptide
MALLDLQAMDTPQEEAVGDLATGSQISLLICEYSSLSVTLCTP
>NZ_CP014485.1|WP_061404445.1|2988447_2990343_-|ABC-transporter-ATP-binding-protein
MTAAPADAARARATPAPPPAEGRLLREAVRRGRGPAALVLAATALGAAAAVTLPLALGRAVDLLIARADAGSWVLLCTALIATEVATDALVARTGGRTGAATTAWLRRRALAGFLAAPPAATTGTGLPTRLTANALDAGTAPVAAATAAAAGLAPLGGLAGLFLVDPWAGAAFVCGVPLLLLILRALLRDGRAALTTYQEEQGRMARLLTGALSGAATIAAAGTVRAEERRVLAPLAGMRAAGERTWRVQGRAAGLSGALMPLLVAAVLAVGGVRLVAGHLTPGDLLALSRYAVLAAGAGALAGALNGWVRAKAGTARVETVTALPPTPHGTRDLPPHGDGTLALHGVHVTRDGVPLLDSVTLTLPGGTTTALVGPSGSGKSLLAAVAGRLTDPDQGTVLLDGTDLRTLSADTLRHAVAYAFERPALFGATIAHAVACGPLPEPELRRALRRAAADTFTDRLPHGPRTPLPEAPLSGGELQRLGLARAFTRPTRLLILDDATSSLDTVTAHLVARALTDTPGTRLTITHRLTTAAQSDQVVWLDGGRIRGTGPHSVLWRDPAYRAVFGAGAGGDAGAGADTVTDTGARRRSDVRTDVTGDVRTELPTDMRTDLHTGIRTDPRVDTGTGAAE
>NZ_CP014485.1|WP_061404444.1|2986519_2988451_-|ABC-transporter-ATP-binding-protein
MTRPRHTDGAPSPLLRPALTFARRRKGPLGALGAWSLLESARTFLTGYAVARALDDGFLAGDVRTGLLWLLALAAAALAGGFADAGVFRALGGVIEPLRDSLVRRVVRATLTRAVASPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSAGAFTGLAALSPRLLPLVLIPLTAGLALFAATLRPMAARQRDLLDADEHLAAFAGRTDHAARDIAATGAAPLVTAEAAPLITAEATAASALARWSAVRVTALGLAAHLPVATLLLAAPTLLSTGLTPGELLAALTYVTTALLPAVNALLTALGAAGSRLLVVLHRLLGEEADAADVREEQAHALRVDDGPRAPGACSQGKADDEVPAIPAPSLPREPVHGPEPFRAEPSPPGPRPTRGPRPTRPALPAVTLRGLTFAYGPDAAPVLDHLDLTVEPGEHLLVVGPSGAGKSTLLALLAGTAHPRHGQIHLAGHTARHARTLGTAARVLVPQEPYIFEATLHDNLTYLAPNAPAPRITEAIHTFTLTPLAADPARPLRPDHLTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAFASHPATVITVSHHFPAPEPGQRVLLLDGATPYLGTHASLLRESALYGELAAGLGEPSAAGSRGTAST
>NZ_CP014485.1|WP_010643339.1|2985347_2986058_+|response-regulator-transcription-factor
MIHSSGVLRSALVALLERERFQVTSASGFSRASSGTTGAPGTPGAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAGAGAERAGIGLAGASRGRAALVVLAGAEHPGVLRLAYAAGALGLVDRDGPANHLATAIRLAAGGGRYVDDGLAMSLLRAMDMPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYIASATRKVGARNRVDAIRISRAAGWV
>NZ_CP014485.1|WP_059214163.1|2999559_3000624_+|YihY/virulence-factor-BrkB-family-protein
MKQPARTAGGAVAEEARTVEGVEGDGPVKGEPGRTVEWWVALRRTPGAFWRDDISDFAAALTYYAILAVLPALLVVVIAFGLVSPDTAERFVGQVTAWAPGGSGASLREVLTRVVRVDSTAWTLLVTGGASALWSASSYLAVSRRALHRMYGVRDRRSPWGKAHRIVATALALLALLLVSSLLLMLTEPVAESIGRLLGLDAGVAWAWSVLRWPLLLCLVACLVVVVFRNGPVAARRRAHSIPGGVLAATLWLTASAGLALYASVLSTYSRLYGSLAGIVVFLVWLWLSNVALLLGAQFTAELCRAAGGPGAPACHPEPAEEVAAQDASAGAEDPEDTADAEETREHGRAPTGA
>NZ_CP014485.1|WP_037629850.1|3000990_3002700_+|acyl-CoA-oxidase
MRTVAAAIPDPRALALSAPALTALHEWAGPADPGMATLASIHYNLFLGSLLDHDHAERDLEPWLRMDRIGTFLCTEAEHGNDAVNMETTAEYDRASRQFVLNTPGPGAAKWMPNTSLTGGPKDAVVAARLLVDGRDLGIFLFLTPLSDERGHLPGVSVERLPHTSGAPVDHCATRFHHVRLPHSAMLQGDHGRLSPDGEFESTLGSPRIRFLRSIGRVSMGKLCMSGYSLGATRQAVAVAVRHGSTRLTSGMTKGRRVPLMAHRSHHEPLLDALATTYAATLLHRSVVRQWEVAEEAEREEVDRLVAVTKGWITWAARETMTTCRERCGAKGLLLTQGIAGQLAANEGTITAEGDNQVIWVKAAGELLMGGFTPKPPSETAPEQRSLRDGTHLQDLMADVERIWHERARTRLRTGGVRGNPMARWNGAVTPALELVAAHAHRLAGEALLEGSDRVTGDEAERIRDLHRLFALRQVAAHSGELLAGERLTAEQVRRLPDEVERVVADLEPHALALTERFFVPEQVPGSDPAGLVEAADLVEPVPEAVAGALPAGAESRAGGLRESEPDAT
>NZ_CP014485.1|WP_018471168.1|3002811_3004128_-|cytochrome-P450
MHDANFAADPQALYEQLREQGPAGPVELAPGVDATLVVGYETALRVLQNPTSFPRDARRWAALNEGRVPMDSPVLPMMAYRPNALFTDGAVHLRLRKAVTDSLAKLNITRIRRDVEPIADYLIDQFSERGRADLLAEYAKLLPLLLFNKLFGCPADIGDTLTTEMSAMFDGKDPVRTKARLDACLMQLIAIKRREPADDVISWLIQHPAGLTDEELKDQLVMLMGAGIEPERNLIGNALLELLSGGAGGRGAGMMVEEAVDHVLWHRTPIANYAAHYPAQDTDFGNGVIAPAGSPVLISFAGANSDPALAEARRSAGRGAHLAWGAGSHACPAKDPAQVIAVTAVEKILNALPDLTLGVPEEDLQWRPGPFHRALVSLPVAFSPTPATRMAAALQNRGIPQQQAAPATPQPQHTAPASSDGGGRRKGFWSSFLDIFRV
>NZ_CP014485.1|WP_008406866.1|3004261_3004870_-|ATP/GTP-binding-protein
MDSNPSSAETAQGPLYVSEAVTTAAKILVVGHFAVGKTTLIGALSEIKPLRTEEKMSQASVQFDDLSAAPDKRTTTVALDFGRLTLADDLVLYLFGTPGQQRFMQLWEDTARGALGALLLVDPARLEETFPVIDLIESYGLDYAIAVNSFTPEQKYGEDEVREALDLLPDTPVVYCDARDRESSARALIALVRHLLTRERVA
>NZ_CP014485.1|WP_003950005.1|3004844_3005219_-|DUF742-domain-containing-protein
MTRPGEEASVTSDFVRSYVITGGRTLPAGDQLALQTLVTIAPERTLPLGASPEVKAIWELLGGGYLSVAEVAAHVALPVGVARLLLTDLLDQGHLLRRAEPPRAQNVERDTLEKVLNGLQSLIG
>NZ_CP014485.1|WP_003950004.1|3005215_3005617_-|roadblock/LC7-domain-containing-protein
MKTDLSWVLNDVLEVRGARHAILVSGDGLLLQSSDGIERGEAETNAAAMSSMQSLSRAVASFVGLGRGVWKQTLMEYDGGWIFLIAAGQGAYLAVSAAVDVDMESMSIRMQKTVASLSRAMGVAPRSNNGVSV
>NZ_CP014485.1|WP_010643360.1|3005613_3006636_-|sensor-histidine-kinase
MGARHAHDVADVRADAESATKAVLKSAMGTLQSLAEEQQLLLDGLLKKYGNDAEVLGDLMSVDHTGSQFSRRAKGISVLCGGWLGRRDGTATVYDVARSAQGRIKDFGRVSVHSQVNVAVTSKAVEPVAVVLAELLENATNYSAPGTPVEVNIQAVPSGVCFIVDDAGLGMDQETKDRAATLLASDGTVDITSLGDPPRVGFAVSGMLAARYGFAVSVGSVSPYGGVRAVIRVPEELLTTEFNEPAQAPARVEAVPALPPQHLTAVPDADTPYVVGTTTGGLPKRRRRAGEVAAKAAAEPATTVETPAADSEMTASRLGAFARGTRIGRDTMTTEGPEYQ
>NZ_CP014485.1|WP_061404449.1|3007156_3008227_-|hypothetical-protein
MGIESDQLVFDYLSRVGDLAQQRQVPAAERMRLITELRRDIDQRRARPGGDSPAAVRRALGKLGTPAEVVAKAGGTSAVAEAPAHTPVPPPRPAEPEPRPARPSLRKVFPAPREEAEPPPPPRRVPGLEDVGRGVSGPDLAGASPDWWRVEATPEGLGGGGGAGTYGARLPGEFAGFQGGVEVPELLNPGVRMDKPEAPGAAKGKAEKDEAAAEAEAALAEAAEDPLGTAAPRRRRFSPRALVGGGLGSPLLLLAAALLVAGAILGNLFCLLLGWLTAYLTKRLTPVQAKFAALGIPALTLLGGAVWLWGRTEGRWGEPIPQAGMADAIGELWPVLLRTAAVASAVFLLWRARRRG
>NZ_CP014485.1|WP_008406841.1|3011342_3011603_+|hypothetical-protein
MTDPKPDRAAPLGDLGPGTRQRRQLRFRALDIAWTALFTVLLLWGVTAAVGALRGDTTWAYSVVAGVLLAGALGLRLTLPRRQIRE
>NZ_CP014485.1|WP_030310290.1|3011614_3012154_+|hypothetical-protein
MNRLHTFLTRNLWAQVALSVLGASALVLLISPGESPTAVLIRVAFSSLGGVAVLLAVRRKEKRATGTDTTGLVTLDGRIRSGDVPTDPAEREALRALVAKRLHRTRNRPWALAFLVLLFGGVTVLTALTAGPRETIGFGILAVTFPVWIYFQGRKQLRRLHRMREALREEERGVTQHAA

Crispr_ID: NZ_CP014485_15

• CRISPR_ID: NZ_CP014485_15
• CRISPR_location: 3138436-3138750
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NZ_CP014485_15

Consensus_repeat	Method
AGCCCGGCCGGCGTTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP014485_15

>15.1|3138459|38|NZ_CP014485|CRISPRCasFinder
CCTCCCGGCCCCGGCAGGCGTCCGGGGCCGCCGGTCGA
>15.2|3138520|41|NZ_CP014485|CRISPRCasFinder
ATCAGTGACCGCCACGGTCGATACGGAGCCCGGCCAATGAC
>15.3|3138584|29|NZ_CP014485|CRISPRCasFinder
CTGAGCCCGGCCGGCGCTTGAGGCCACCG
>15.4|3138636|40|NZ_CP014485|CRISPRCasFinder
TTCTGGACCGGCACCGTTGAGCCGGTGCTCAGCCGACCTC
>15.5|3138699|29|NZ_CP014485|CRISPRCasFinder
CCCAGCCCGGCCGGCGCTTGAGGCCACCG

CRISPR arrays and Neighbor proteins around NZ_CP014485_15

CRISPR arrays

The CRISPR arrays of NZ_CP014485_15

>merge|NZ_CP014485|15|3138436-3138750|CRISPRCasFinder
AGCCCGGCCCGCGCTTGAGGCCGCCTCCCGGCCCCGGCAGGCGTCCGGGGCCGCCGGTCGAAGCCCGGCCGGCGTTTGAGGCCAATCAGTGACCGCCACGGTCGATACGGAGCCCGGCCAATGACAGCCCGGCCGGCGATTGAGGCCACTGAGCCCGGCCGGCGCTTGAGGCCACCGAGCCCGGCCGGCGATTGAGGCCGTTCTGGACCGGCACCGTTGAGCCGGTGCTCAGCCGACCTCAGCCCGGCCGGCGCTTGAGGCCACCCAGCCCGGCCGGCGCTTGAGGCCACCGAGCCCGGCCGGCGTCTGAGGCCA

>NZ_CP014485|15|11|3138436-3138750|CRISPRCasFinder
AGCCCGGCCCGCGCTTGAGGCCG	CCTCCCGGCCCCGGCAGGCGTCCGGGGCCGCCGGTCGA
AGCCCGGCCGGCGTTTGAGGCCA	ATCAGTGACCGCCACGGTCGATACGGAGCCCGGCCAATGAC
AGCCCGGCCGGCGATTGAGGCCA	CTGAGCCCGGCCGGCGCTTGAGGCCACCG
AGCCCGGCCGGCGATTGAGGCCG	TTCTGGACCGGCACCGTTGAGCCGGTGCTCAGCCGACCTC
AGCCCGGCCGGCGCTTGAGGCCA	CCCAGCCCGGCCGGCGCTTGAGGCCACCG
AGCCCGGCCGGCGTCTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061404492.1|3135701_3136970_+|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl|CDD|234960
NZ_CP014485.1|WP_003949850.1|3145474_3146536_-|cobalamin-B12-binding-domain-containing-protein	unknown	unknown	gnl|CDD|227345
NZ_CP014485.1|WP_008409854.1|3143503_3144043_-|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NZ_CP014485.1|WP_003949857.1|3139892_3140204_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404491.1|3131902_3132535_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008409858.1|3138843_3139806_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223566
NZ_CP014485.1|WP_003949867.1|3130281_3130917_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014485.1|WP_003949852.1|3144170_3144521_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP014485.1|WP_030307725.1|3143131_3143476_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133394
NZ_CP014485.1|WP_003949851.1|3145044_3145428_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP014485.1|WP_003949856.1|3140382_3141894_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NZ_CP014485.1|WP_008409865.1|3133773_3135486_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|215457
NZ_CP014485.1|WP_003949863.1|3132710_3133631_+|diiron-oxygenase	unknown	unknown	gnl|CDD|378680
NZ_CP014485.1|WP_059213795.1|3131307_3131859_-|CrcB-family-protein	unknown	unknown	gnl|CDD|376809
NZ_CP014485.1|WP_049978317.1|3137485_3138271_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238870
NZ_CP014485.1|WP_003949866.1|3130933_3131311_-|fluoride-efflux-transporter-CrcB	unknown	unknown	gnl|CDD|223317
NZ_CP014485.1|WP_061404490.1|3129022_3130285_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP014485.1|WP_003949855.1|3142342_3142546_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP014485.1|WP_015507393.1|3127864_3128773_-|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176231
NZ_CP014485.1|WP_003949849.1|3146532_3148221_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_061404492.1|3135701_3136970_+|tRNA-4-thiouridine(8)-synthase-ThiI	gnl|CDD|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	3.53465e-167
NZ_CP014485.1|WP_003949850.1|3145474_3146536_-|cobalamin-B12-binding-domain-containing-protein	gnl|CDD|227345	COG5012, COG5012, Predicted cobalamin binding protein [General function prediction only].	7.02863e-19
NZ_CP014485.1|WP_008409854.1|3143503_3144043_-|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	3.3871e-15
NZ_CP014485.1|WP_003949863.1|3132710_3133631_+|diiron-oxygenase	gnl|CDD|378680	pfam11583, AurF, P-aminobenzoate N-oxygenase AurF. This family is a metalloenzyme which is involved in the biosynthesis of antibiotic aureothin by catalyzing the formation of p-nitrobenzoic acid from p-aminobenzoic acid. AurF is a non-heme di-iron monooxygenase which creates nitroarenes via the sequential oxidation of aminoarenes.	5.73174e-103
NZ_CP014485.1|WP_003949867.1|3130281_3130917_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.64385e-68
NZ_CP014485.1|WP_003949852.1|3144170_3144521_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.3583e-20
NZ_CP014485.1|WP_030307725.1|3143131_3143476_+|MerR-family-transcriptional-regulator	gnl|CDD|133394	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator. Helix-turn-helix (HTH) transcription regulator HspR, N-terminal domain. Heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	7.07293e-09
NZ_CP014485.1|WP_003949851.1|3145044_3145428_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	4.95743e-15
NZ_CP014485.1|WP_008409858.1|3138843_3139806_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	8.9512e-42
NZ_CP014485.1|WP_008409865.1|3133773_3135486_+|FAD-dependent-oxidoreductase	gnl|CDD|215457	PLN02852, PLN02852, ferredoxin-NADP+ reductase.	6.06211e-118
NZ_CP014485.1|WP_003949856.1|3140382_3141894_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.35115e-118
NZ_CP014485.1|WP_059213795.1|3131307_3131859_-|CrcB-family-protein	gnl|CDD|376809	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB). CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.	9.43927e-33
NZ_CP014485.1|WP_049978317.1|3137485_3138271_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	2.87627e-62
NZ_CP014485.1|WP_003949866.1|3130933_3131311_-|fluoride-efflux-transporter-CrcB	gnl|CDD|223317	COG0239, CrcB, Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning].	6.43239e-31
NZ_CP014485.1|WP_061404490.1|3129022_3130285_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.00674e-53
NZ_CP014485.1|WP_003949855.1|3142342_3142546_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.10682e-34
NZ_CP014485.1|WP_015507393.1|3127864_3128773_-|zinc-binding-dehydrogenase	gnl|CDD|176231	cd08270, MDR4, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.58522e-103
NZ_CP014485.1|WP_003949849.1|3146532_3148221_-|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	7.95409e-39

Protein sequences

>NZ_CP014485.1|WP_049978317.1|3137485_3138271_-|SGNH/GDSL-hydrolase-family-protein
MSVVRYVALGDSQTEGLGDGDEVSGLRGWADRLAELLDAAEPGLQYANLAVRGQLAGQVRATQLDAALALRPDLATVVAGMNDLLRPRFDADAVGAELEAMFAALTGAGARVATLTFPAMERLVPLARPLAPRVPALNARIREAAARHGVLVVETYGEEVVVDPRLWSPDRLHAAPLGHARIAAAFAHALALPGSDRGWAVPLPAVPPVRGVRALAAEARWVSGFLGPWLGRRVWGRSSADGRVAKRPGLAPLGTAGRAGD
>NZ_CP014485.1|WP_061404492.1|3135701_3136970_+|tRNA-4-thiouridine(8)-synthase-ThiI
MNAVVPAQGVPDLAGPVPIGPCVLLKHGEVFLKGRNRHLFVERLHDNLRGALRGVTGSIWIKEMQNVTVLGGDAPQDELIARARRVMGFVAVQPAMRVETGEEAIVAAAVAALDGAAPGTTFAVRARRRHKPFPLTSTQLERLVGARIQEAHGLPVDLTRPDIRVEVEIDRKESYVSGLRHTGQGGLPVGTSGRALVLLSGGYDSPVAAHRAMRRGLRCDFVHFTGAPYTNAASAFKAYALARELNRYQPPGKLHIVALGHAQKQLAVAGAGRFQVVGQRRLMVKAASVLARRLRAQALVTGDALGQVASQTLSNMALVDEAATLPVLRPLIGWEKQEIIDEARRVGTAEISVLPDEDCCQLLAPRQVSLRTKLEDVAGFEKRLDADELIDQMLASAQVTRPGTDETPAPATPPAASACGTD
>NZ_CP014485.1|WP_008409865.1|3133773_3135486_+|FAD-dependent-oxidoreductase
MTYAITQTCCNDATCVAVCPVNCIHPTPEERAFGSTEMLHIDPRSCIDCGACADACPVDAIFPVDRLKPAHREYAALNAAYYEEEATTTEREEAAAAPASVTGDGAEAQAEAAERTGPLFRAWDAPGFARSLPSDFAPLRIAVVGTGPAGMYAAEDLLLHTDAQVTLVDRLPVAGGLIRYGVAPDHPATKKVGEAFARFHHHPRVRMQLGLEVGKELSAAELAAHHDAVIYAVGAATDRRLGIPGEELPGSVSATGLVAWYNAHPDHAPDAVSLDAERVVVVGNGNVALDVARILVSDPDTLAATDIAGHALDALRGRRVREVVLLGRRGPEDAAYTRTELLALGHLDGVDLVVDDHDPRIGAAIDAAGPLDKAGMLGGVTRTAVDWSRPPEPGRRIVFRFHSAPLAVTGEQAVTGVQVTGGTEIPAQLVVRSIGHRGVAVPGLPFDETTGTVPHEGGRVRGRSNEYVVGWIKRGPSGGIGANRSCAAETVTTLLADAVAGGLPTPSGSAKEFARLARRRNRRLVDARGLAAIERAERESGQRDGRVRTKFATVPELVAAARRSRLRLPG
>NZ_CP014485.1|WP_003949863.1|3132710_3133631_+|diiron-oxygenase
MATTDAQPAAQDEGGHDINDITRRLLESSAKLSYDPATEVDWDTPLDKSFHGMSPEWSSLYGTRYWDELTEDQRKELTRQESGSVASTGIWFEVILQQMVLRDIYAKDPGSPEFQWALTEIADECRHSIMFARGVRKLGAPAYKPRRAVMELGRLFKTLAVGEAAYASILVAEEVLDVMQRDWMRDERVVPFVRTINNIHVVEESRHMKFARDETIKRLEKAGWLRRNVQALVISICAYFVITSMWNRDVYRNAGLNTERALAEAKANQHHKSMIRSSCSGLMDFLASAKLLTRPAAAVYRRANLL
>NZ_CP014485.1|WP_061404491.1|3131902_3132535_+|hypothetical-protein
MRPPAAPAPAHPPGPEPEPEWNVALRRLLGDPYVFVATGPRRHEEWARDVLAVLRREVADPRGRPGLDADRTGPGRDAVPAYPFAPPPAERFPAYLRPLERAAAVGALAVMSEEWQFEPAPVRSRPDREAFLADARTLLDRYGPDAEYWTNAVAAGSGPAPDFVAAGLRGTASYTFLTGAYVNGLDLCDDLGLIAVSADEVGVFWSVGAC
>NZ_CP014485.1|WP_059213795.1|3131307_3131859_-|CrcB-family-protein
MSHPPHTPDGAAPDSAESHRANLPLPPPEPVDPDLGPELAPGERPESQAPVLLAIALGGGLGAVIRYGATVLWPTPAGSFPWTILVVNVVGCAAMGVLMALLTEVWPEAPRLTRPFLGTGVLGGFTTFSTYAVDVQTLFDGGSPGRALGTLALTVAAALAAVAGASWLTRSAVRLGRAEGSLA
>NZ_CP014485.1|WP_003949866.1|3130933_3131311_-|fluoride-efflux-transporter-CrcB
MTWLLVVVGGMIGAPCRYLMDRAVQRRHSSGFPWGTLAVNMSGSLVLGVLVGARLTGAAPENLMVFAATGFCGAYTTYSTFSYETLRLAETGARGAAFANVALSVSAALGAAVMGLGVAKAVWGG
>NZ_CP014485.1|WP_003949867.1|3130281_3130917_+|response-regulator-transcription-factor
MTVIRLLLADDHPIVRAGLRAVLETEPDFEIAGEAASAEEAVALAGRLAVDVVLMDLQFGPGARMNGSEATAAITARPGAPRVLVVTTYDSDADTLPAIEAGATGYLLKDAPPEELAEAVRTAAAGRTTLAPAVADRLLRRMRTPGTALSRRETEVLGLVAEGMSNLRISERLHLSQATVKSHLVHIYAKLGVDSRTAAVAAALERGLIRR
>NZ_CP014485.1|WP_061404490.1|3129022_3130285_+|sensor-histidine-kinase
MPSTTPAPAPPRAPLSTPAPRVLAWCLHLLVAALLVMAVGRALVDGGGQGWAVVVAGVAFGAVYAAGPVVPGVRESRRGAVVWLVAVGVLWAGLLGLTADAMWLAFPLFFVQLHLLAGRAGPWAVALTTGVAVCSYAAHQGGFTAAAAIGPVIGAAVAVAVVRGYQALYRESEQRRRLIEELTRARADLAAAQHTAGVLAERERLAREIHDTLAQGLSSIQLLLRAAQRSLGGEEGAGRYVEQARQAAADNLAEARRFVAALAPQNLEGTTLAGALERLCATTSATAPLTVRFHLAHDPGPLPAAYEVALLRIAQAALGNTVRHAGARTAEVTLSGLGDAVALDVVDDGRGFDPAALPAPDPDRGGFGIPAMRARARALGGTLTIESRPGGGTAVAAQLPLPAEGTRPHPDPDPVPEAPR
>NZ_CP014485.1|WP_015507393.1|3127864_3128773_-|zinc-binding-dehydrogenase
MRALVVEHGSSGPVRFAEVDEPVPSRDQALVAIRHIGLNFGELNYVDQWPAGAVHGHDASGVVVRAAADGSGPPEGTRVALGMSAHAWAERVAVDPASLAAVPEGVELADGAAPGIAGVTALRVLRTRSLLARDVLITGAGGGVGRFAVQLAALAGARVTALVGSPDRAAGLRALGADEVLTSLAGTESRFDLVLDTVGGPLLAQAWDRLAEGGTLHAVGYSSGQDTTFPSGTLFGFGAPRTLATFGDMTPTSADLTELLDLMAAGKLSAPVGRRGVWQDVDDAVQALFARKVHGKIVLDVV
>NZ_CP014485.1|WP_008409858.1|3138843_3139806_+|NAD(P)/FAD-dependent-oxidoreductase
MPTPHTYDVVVIGGGAAGLAGAVTLGRARRTVLVVDAGTPRNAPAAGVHTFLSREGVSPAELLRTGRAEVTSYGGEIREGTVTDARREGDGFVVTLADGSEVSARRLLVTTGITDELPPVQGLAALWGKDVLHCPYCHGWEAQDLPTGVLATGPLSVHQALLWRQWTDDLTLFTHTTAGPTPEEREQLEARGTRIVDGEVTGVETDGEGRLAGVRLADGSTVPVRALATGGTLTARAGFLARLGLETVPVEVGGTVIGSRLDTDATGLTSVPGVWAAGNVASPTDQVVISAGAAVRAAAVLNMDLVTEETRRAVEARRAG
>NZ_CP014485.1|WP_003949857.1|3139892_3140204_-|hypothetical-protein
MRCVIARFPFDLVKSEVVAKMKGVKPEPVTGEYVIIGRHHYPVKQVGEVITRQDRRDFSAGEVTRALTRLGFTCRPAPGTEPAVERTAVETAAAQLGGAPEQG
>NZ_CP014485.1|WP_003949856.1|3140382_3141894_-|DEAD/DEAH-box-helicase
MNQNRASRDDNRTGRRSGGGHRGAGAPRSAGPDRFRSPGRGGPQGARRSGGERTRAGARGEFAPPVTGTPALPPVDAFDQLGLPAPLLACLTAQGVTEPFPIQAATLPNSLAGRDILGRGRTGSGKTLAFGLALLARLEGRRAEPRSPLGLVLVPTRELAQQVTEALTPYARALRLRMTTVVGGLSLGRQASALRGGAEVVVATPGRLKDLIDRGDCRLDQVGATVLDEADQMADMGFMPQVTELLDQVRPGGQRLLFSATLDRNVDLLVRRYLDDPTVHSVDPSAGAVTTMEHHLFQVHGPDKHALATEIAARDGRVILFLDTKHAVDRLAEHLLRNGVRAAALHGGRSQAQRTRTLTQFRDGHVTALVATNVAARGIHVDDLDLVVNVDPPADHKDYLHRGGRTARAGASGSVVTLVLPEQRRSMSRLMADAGITPQTTRVRSGEAELSRITGARTPSGVPVVVRAPAPASPRRGASSSRGRRSPAAQARRAAAVRARPAA
>NZ_CP014485.1|WP_003949855.1|3142342_3142546_-|cold-shock-protein
MATGTVKWFNAEKGFGFIEQDGGGADVFAHYSNISAQGFRELIEGQKVSFDVTQGQKGPQAENIVVA
>NZ_CP014485.1|WP_030307725.1|3143131_3143476_+|MerR-family-transcriptional-regulator
MQVTRKTPPDPADKFDDEDYPAYTMGRAAEMIGATPAFLRAVGEARLITPLRSAGGHRRYSRYQLRVAARARELVDQGTPVEAACRIVILEDQLEEALRVNERLRDAASAAPRD
>NZ_CP014485.1|WP_008409854.1|3143503_3144043_-|ATP-binding-protein
MTVDEGDGDLIQYRQGAARAGNGRRPAQAPRIVEAPQHRQTRRTPQVPGTAGEARALVQQALRDSFGPDATGDSDDGLGDTVVVADALLVTSELVTNAIRHGGGLTGFDVQLEESHLTLHVSDASPELPAATRPDGPFDPDRPLVGGYGWPLVRRLCREVSVRPLPGGGKCVTVTLSLV
>NZ_CP014485.1|WP_003949852.1|3144170_3144521_-|STAS-domain-containing-protein
MLERSRMDITTSAELSAFVIGVHGDVDLHTAPALDAALAQALRAETPRTVVDLSGTGFADSSILGSLLRALRDHREKGRRLILAGPMSDLVTRLFEVTGTLAAFETAPDVRAAREQ
>NZ_CP014485.1|WP_003949851.1|3145044_3145428_-|STAS-domain-containing-protein
MTPLNDPDDPDDLGGTGLTLTAEPAAPGTLALRLAGALDHESADALVREVARRLAERPAPRLLRLDCAGLTACDSLGLSALLMIGRRTGAAACALRLDRRPPHLDRLLEITGTHGYLVGPGEEPGPA
>NZ_CP014485.1|WP_003949850.1|3145474_3146536_-|cobalamin-B12-binding-domain-containing-protein
MTTRTPEETVTAAEPLRALLWDALLAGDEYAAADVLFAALDDGLSAEEALLDVIGPVQAEVGLGWAANRLSVVQEHAATAMNDRIIAALAHRSPPPGEGRGRIAVACVEGEWHALPARLLAETLRLRGWRVDFLGAQAPTPHLIAHLHQTGPDLVALSSSIPTRLPTAHAAITACQAAGVPVLAGGAAFGADGRYARLLGADGWAPDARSAADVAAGGLGVPSGAVLHEPVDDLPHLADQEYTLVSRGRTRLVRETVDGLDDRFPAMRGYTERQRERTAEDIAHIVDFLATALYVDDDALFTSFLVWTAGILEARGVPARSLTPALELLGEPLRDFPRATRLLHRGGAALTGG
>NZ_CP014485.1|WP_003949849.1|3146532_3148221_-|serine/threonine-protein-phosphatase
MDVTKSSTIGAPRARTGRTAAPGAWDEAPCPVLVADAAGAVVTANAHATALFPAAVPGALLSDAVPEWLGAAHRAAVAGQEPGDAVSGAVGERVYRAVARPAAGGGSRGAGAAGLVWWLSDDTGRAEAEAALAVERARTAFLSEASNALLATLNTERCMEVTAQLAARHLADGVVVVLPGAGRRTPLAWAVDGGGSTRALLALDPAEVPGLAEALQGFPPVPSRWIDPEALPTWAVPEEFDGPVCAVAVIPLPGHGVPAGALILLRREGKRGFTEPEEVFARLFAARAGAALSAARMYAEQAAVTQTLMRELLPPRLEQIRGVEFAGGYRASERGERVGGDFYDVHPTAGEAGASLVVLGDVCGKGLDAAVLTGKIRNTLQALLPMADDHPRVLRMLNDSLLSSHHTRFATLVLASAVREGDAVRLDLTSAGHPPPLLVRADGTVEAADTRGSLVGALPEVEATTARVTLRAGETCLLYTDGVTEARGGPFGDRMFGEERLREALAECAGMPAEAVVERVQMLAAQWVGAGEHDDMAMVAVTVPRKSPGGVVSAAGRGRGSA

Crispr_ID: NZ_CP014485_16

• CRISPR_ID: NZ_CP014485_16
• CRISPR_location: 3190048-3190248
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP014485_16

Consensus_repeat	Method
TCAGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP014485_16

>16.1|3190073|33|NZ_CP014485|CRISPRCasFinder
CTTGACAGCCCGGCTGGCGCTTGAGGCCACTCC
>16.2|3190131|37|NZ_CP014485|CRISPRCasFinder
TCGCTGACCGGCACGGTCAATCCCACCGCACCCCCAA
>16.3|3190193|31|NZ_CP014485|CRISPRCasFinder
AACCCAGCCCGGCCGGCGCCTGAGGCCAAAC

CRISPR arrays and Neighbor proteins around NZ_CP014485_16

CRISPR arrays

The CRISPR arrays of NZ_CP014485_16

>merge|NZ_CP014485|16|3190048-3190248|CRISPRCasFinder
TCAGCCCGGCCGGCGCTTGAGGCCACTTGACAGCCCGGCTGGCGCTTGAGGCCACTCCTCAGCCCGGCCGGCGCTTGAGGCCATCGCTGACCGGCACGGTCAATCCCACCGCACCCCCAAACAGCCCGGTCGGCGCCTGAGGCCAAACCCAGCCCGGCCGGCGCCTGAGGCCAAACCCAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP014485|16|12|3190048-3190248|CRISPRCasFinder
TCAGCCCGGCCGGCGCTTGAGGCCA	CTTGACAGCCCGGCTGGCGCTTGAGGCCACTCC
TCAGCCCGGCCGGCGCTTGAGGCCA	TCGCTGACCGGCACGGTCAATCCCACCGCACCCCCAA
ACAGCCCGGTCGGCGCCTGAGGCCA	AACCCAGCCCGGCCGGCGCCTGAGGCCAAAC
CCAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_008410364.1|3189742_3190021_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_030307792.1|3193175_3193856_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008410335.1|3194620_3195925_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|274368
NZ_CP014485.1|WP_003949795.1|3191957_3192440_-|CarD-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224248
NZ_CP014485.1|WP_003949801.1|3183867_3184278_-|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274679
NZ_CP014485.1|WP_008409794.1|3182375_3183776_-|cysteine--tRNA-ligase	unknown	unknown	gnl|CDD|234705
NZ_CP014485.1|WP_015507413.1|3179528_3181121_-|DoxX-family-membrane-protein	unknown	unknown	gnl|CDD|236090
NZ_CP014485.1|WP_008409796.1|3181296_3182235_-|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB	unknown	unknown	gnl|CDD|223640
NZ_CP014485.1|WP_003949789.1|3197422_3197746_+|multidrug-transporter	unknown	unknown	gnl|CDD|224987
NZ_CP014485.1|WP_031177882.1|3184328_3185594_-|MFS-transporter	unknown	unknown	gnl|CDD|340887
NZ_CP014485.1|WP_075986682.1|3192401_3192638_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008410337.1|3193943_3194624_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP014485.1|WP_061404502.1|3197735_3198299_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225767
NZ_CP014485.1|WP_061404501.1|3190282_3190798_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|178851
NZ_CP014485.1|WP_061404498.1|3185590_3187357_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224094
NZ_CP014485.1|WP_003949796.1|3190787_3191585_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|234670
NZ_CP014485.1|WP_003949791.1|3196111_3196792_+|phosphate-signaling-complex-protein-PhoU	unknown	unknown	gnl|CDD|273990
NZ_CP014485.1|WP_061404500.1|3188991_3189606_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP014485.1|WP_061404499.1|3187391_3188933_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173855
NZ_CP014485.1|WP_003949805.1|3178393_3179416_+|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008410335.1|3194620_3195925_-|two-component-sensor-histidine-kinase	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.2459e-81
NZ_CP014485.1|WP_003949795.1|3191957_3192440_-|CarD-family-transcriptional-regulator	gnl|CDD|224248	COG1329, COG1329, Transcriptional regulators, similar to M. xanthus CarD [Transcription].	1.13617e-68
NZ_CP014485.1|WP_003949801.1|3183867_3184278_-|PPOX-class-F420-dependent-oxidoreductase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	6.47275e-41
NZ_CP014485.1|WP_008409794.1|3182375_3183776_-|cysteine--tRNA-ligase	gnl|CDD|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NZ_CP014485.1|WP_015507413.1|3179528_3181121_-|DoxX-family-membrane-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	4.54404e-08
NZ_CP014485.1|WP_008409796.1|3181296_3182235_-|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	6.46343e-77
NZ_CP014485.1|WP_003949789.1|3197422_3197746_+|multidrug-transporter	gnl|CDD|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	2.05166e-20
NZ_CP014485.1|WP_031177882.1|3184328_3185594_-|MFS-transporter	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.72116e-57
NZ_CP014485.1|WP_008410337.1|3193943_3194624_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.50602e-94
NZ_CP014485.1|WP_061404502.1|3197735_3198299_+|TetR-family-transcriptional-regulator	gnl|CDD|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	1.34374e-15
NZ_CP014485.1|WP_061404501.1|3190282_3190798_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.58986e-73
NZ_CP014485.1|WP_061404498.1|3185590_3187357_-|ABC-transporter-permease-subunit	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	9.1022e-44
NZ_CP014485.1|WP_003949796.1|3190787_3191585_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl|CDD|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	8.35528e-79
NZ_CP014485.1|WP_003949791.1|3196111_3196792_+|phosphate-signaling-complex-protein-PhoU	gnl|CDD|273990	TIGR02135, Uncharacterized_protein, phosphate transport system regulatory protein PhoU. This model describes PhoU, a regulatory protein of unknown mechanism for high-affinity phosphate ABC transporter systems. The protein consists of two copies of the domain described by pfam01895. Deletion of PhoU activates constitutive expression of the phosphate ABC transporter and allows phosphate transport, but causes a growth defect and so likely has some second function. [Regulatory functions, Other, Transport and binding proteins, Anions].	1.69432e-59
NZ_CP014485.1|WP_061404500.1|3188991_3189606_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.02485e-14
NZ_CP014485.1|WP_061404499.1|3187391_3188933_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173855	cd08490, PBP2_NikA_DppA_OppA_like_3, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.64033e-152
NZ_CP014485.1|WP_003949805.1|3178393_3179416_+|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	3.79596e-72

Protein sequences

>NZ_CP014485.1|WP_008410364.1|3189742_3190021_+|hypothetical-protein
MDSDDERLLRGRVYGHDPTAPEAGPLPGHHYAELVGGPLDGLLLDITTVPPEARPEGAALPTALSTHGPEGRSLYQPRPTTPSRWDWQGDLR
>NZ_CP014485.1|WP_061404500.1|3188991_3189606_-|GNAT-family-N-acetyltransferase
MAVVAGVEAGVRERGEGTGRDAYVVRTASEADVPGARAVMLDTVYRDLRSGYVPRWHADIIDPAAAYLEPERCTLLVVERDGEIVATGAVRDRGPAAPPNPRWVADRFPSGSTAQLCRIYVRPEHRRHGLARRLVRELCDFVVRAGGYERVYLHTDPSVPGAEAFWRATAEEVCDERALPGGGQGIVHFEVPVAGLGRPAAAPA
>NZ_CP014485.1|WP_061404499.1|3187391_3188933_-|ABC-transporter-substrate-binding-protein
MSSQPSKYSVRRRPLLALGAAALLVPVAACGGSTDGGASGGGDQRLRAVMAFPPAQAMSPYGDDAVTLSRLSVVEGLTRIDEEGAAKPALATKWQRDGAKGWEFTLRDARFQDGDAVDAEAVVRSLAAAQDASPKPRVLSEVRLTAEAEGKRTVRITTDEADPLLPQRLANPSLAILSQAAYAKGEKGGKVNPAGHATGPYTLTEVNGAVSAKLDRNDTYWGRKAKAPGVDVKFVADGTARANALRTGTADIAEYVPVAQTSLLDEKQIHEVPTARTNTLYLNTENGVFADPAVRAAARSAIDSKALVDGVYEGRADTARGLLGPGVPWAADARKEPEGRAKAASKAEVAKTKEIVLATYTNRPELPEVASAVQQQLQARGFTVKQYVRDYAQMEADALAGKYDAFIQARNTLLDTADPVSYLGSDFTCEGSFNIAQLCDKGVDEAVAKAAGADGLDARHAAEMEAEAKILGADAAVPLVHERFVQGFDSGKVDGVALDPMERRLITADTRLR
>NZ_CP014485.1|WP_061404498.1|3185590_3187357_-|ABC-transporter-permease-subunit
MKHLAGRALTLLAVLALIGLLPWLTTTDPALTILHARYSDRQPTPEVLDAIRAETGLDGGPAHVLGGWAGGLLHGDLGTSWVSGQPVGPDVTAALTTSLSLMGVSLAVALLLALALSARTLRRGARREATTTRAGVLAAVLAALPEFLLAAVLATVLAVHLGWFPALGWGTPAQAVLPALAMGVPAGALLGRLLDDALPAAFAEPWAKAATAAGLPPRRIARHALRRTLPGLLPQGGLVVVGLTGSAVAVETLFAVPGLGSTALAGALAQDLPVLQAAVLMLLLTGLAAALAVRLLSRVLLGPALTDRALPALVAPRLPARKGVAAGAVVLAVVFCAVLVAGLLRDPLHVDAAARLLPPSAAHPFGTDALGRDVLARLGHGAARTVLLAFAVAAAALLLGLAAGFLRAGALTETVNALPAVLAGLLTAAVAGPGPWGAAAAVAAVAWAPLAAHTEALYVQERAAPHLAAARSLGAGRAHLLRRHLLPAVLPPVTRHALLRVPALALALAALGFLGLGTQPPAPEWGRMLSENMPYVERAPWAVLAPAAALAVLGALAVLLAAAVRGRTGADTATATAPTAPAAREAAA
>NZ_CP014485.1|WP_031177882.1|3184328_3185594_-|MFS-transporter
MSTGTGLRPATSSLREITGLPPYLRLLAGTQFAFNTGFYAVLPYLAGHLGDGLGMAGWLVGLVLGLRTFSQQGLFVVGGALTDRYGPRPVVLAGCLLRIAGFAWLALAGSTATVVAAVVLTGFAAALFSPAVESETAREAVRREQADGTARARTLAVFSAAGQAGAFLGPLLGSLLLAAGGEWGFRAACAAGVAVFVAVFAGHAVLMPRRAAVHRDRPRGGVRHLARNPRFLVLCLTYSTWLLAYNQLYLALPAEVERATGSQAALGWLFALSSLLVVTAQIPLTRHAAVRLAPRTALAGGLALVAAGFALVPVTPGGPGGLLPGAVLVTLLTCGQMLLVPAARGLVPDLVDGRHLGLATGALSSVSGLAVLGGSAASGLLLQAPAPVLWGALAAVPLAGAVAARLLPSGRGGGEAGRAAG
>NZ_CP014485.1|WP_003949801.1|3183867_3184278_-|PPOX-class-F420-dependent-oxidoreductase
MSDTAQLSDALKQKLDTPVFITVATIQPDGSPQLSPVWVKRDGNDVLFSTTVDRRKTKNLRRDPRVTVQVQPFDEPYTYAEIRGRATVTEEGGQELIDELSRKYTGKSYAEFNPASGQDAARVVVRVTPDKVVGRL
>NZ_CP014485.1|WP_008409794.1|3182375_3183776_-|cysteine--tRNA-ligase
MTIRLYDTSARQIRDFAPLTPGCVSIYLCGATVQSAPHIGHIRSGLNFDILRRWFAYRGYDVTFIRNVTDIDDKIIKKSAEQERPWWAIGYENERAFNNGYDALGCLPPTYEPRATGHVPEMIEMMRGLIERGHAYEADGNVYFDVRSFPEYLELSNQDLDELRQPSGEGETGKRDPRDFAMWKAAKPGEPSWETPWGRGRPGWHLECSAMAHKYLGSAFDIHGGGLDLVFPHHENEIAQAKAYGDDFATYWVHNAWVTMAGEKMSKSLGNSVLVSEMVKHWRPIVLRYYLGTPHYRSMIEYSEEALREAESAFARIEGFMQRVTEKAGETPEPATEVPPAFAEAMDDDLGVPQALAVIHTTVRQGNSALAADDKEAAVARLAEVRAMLGVLGLDPYDPHWAGEADRGEDLHGAVDTLVRLVLDQREAARTRKDWATADAIRDQLQQSGLVIEDSPTGPRWTLGPR
>NZ_CP014485.1|WP_008409796.1|3181296_3182235_-|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB
MAANNRRMSGKKGAQIGSGGKRRRGLEGKGPTPPAEARKGHVKNRLANAKAKQQARRPKARPGQRSTSELVVGRNPVYEALRDGVPASTLYVQQFIDNDERVRDALALAAERGGIHLMEAPRPELDRMTNGLNHQGLVLQVPPYEYAHAEDLTAAAYDAGQDPLIVLLDGVTDPRNLGAVVRSVSAFGGHGVVVPERRAAGMTAGAWKSSAGAAARTPVARATNLTRTLEAYKKEGVVVVGLAADGEADVTDLPALEGPVAVVVGSEGKGLSRLVGETCDIRVRIPMPGGAESLNAGVAAGIVLYEAARRRA
>NZ_CP014485.1|WP_015507413.1|3179528_3181121_-|DoxX-family-membrane-protein
MVKVHCDPAQVIVNHASFRVQLPSAQKAQSPRISRLTGGASADTARIPVVGTVTRRRAPVVWSGRSAPGDGGATTGLLQAVRASGVRHGDDPPGATQVIPRVDPDEVATGEIPTLTGHTPGEPLLPRMRSAGSAYDDDTYTPRHGTPAYDGDDGGDRAGTDGGDGSDLDQDGRPKARSSVRHAYYPYRRMNLGVVLLPLRVGLGFATAYAGMSKLCDPAYFDGGERGSLMRWLGSLQPWSLAEPLHGFAVHHPVGVGLLVAFLQVLVGVLTVLGLWQRLAASAGAVLAAGLLITVSWRANPVYSMSDVIYLAAWTPLIIAGAPVWSVDGKLAADAWRKLGPRAELWQLRRWVLKRGLVVATVAVGLTLLFGALLGSAVRDADRVVVPGPGEAPRNSVPGMPLPSESGQVSGSPDASAGPDEAPSGGTSEGPSETSSGPAGSEQRETAGTGTTAPAETQGPGQAPPQQNAPQPPPQTSAGPGDDSSGGGSGEPGGGPGPGDGGGAEEPGEDPADGGSGGGGGPKLVGGLFG
>NZ_CP014485.1|WP_003949805.1|3178393_3179416_+|HlyC/CorC-family-transporter
MSFGLAMFVTVLLLIGSGFFVAAEFALVAAKRHRMEKAAAEGKRGAASALAGMKELSLMLAGAQLGITVCTLGLGSVSKPAVSHALDPVLVSWGLPASLSYGIAFAIAMIVVVFLHMVVGEMAPKSWAIAHPESSAMLLAPPFRGIVTVVRPLIWVMNRISNALVRLCRVTPRDELAEVHNREQLTHLVAESRRLGLISEDDSELITSSLTEPLSPVEALQVPAERIVSVPAGADAETILATAAAHDRSRLLVRDGDRFIGSLHARDALITRARGRKATARALARPLPALTEGDTVGQAIELLRQRRASLALVQDREGRVTGLVSLDDLLARLLHPQEAA
>NZ_CP014485.1|WP_061404501.1|3190282_3190798_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MGTETGPQGQAGFTMPLVGIGTDVHAFERGRQLWCAGLHWEGEEFGLAGHSDGDVAAHAACDALFSAAGLGDLGAHFGTSRPEWAGASGVALLGEAARIVRAEGFQVGNVAVQVVGLRPKVGKRRDEAVAALSAAVGAPVSVSGTTTDGLGLTGRGEGLAAIATALVYRVG
>NZ_CP014485.1|WP_003949796.1|3190787_3191585_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MTDETQAPRTAVVIPAAGRGVRLGPGTPKALRTLHGTPMLVHAVRAMAASRAVSLVVVVAPSDGVAEVRAMVDDHLHPTEAPSFAPARAGGGDETDIVVVAGGETRQESVRRGLDALPADVTTVLVHDAARPLVPVDIVDGVVAAVRGGAPAVVPGLPLSDTVKEVGALAEGATGPGEPVVATPERARLRAVQTPQGFDREALDRAHRQGPVQGEGATDDAGLCERLGLPVVVVPGHEEAFKVTRPLDLVLAEAVLARRRANDGY
>NZ_CP014485.1|WP_003949795.1|3191957_3192440_-|CarD-family-transcriptional-regulator
MTFKVGDTVVYPHHGAALIEAIETRQIKGVDKNYLVLKVAQGDLTVRVPADNAELVGVRDVVGQDGLDRVFEVLRAPYAEEPTNWSRRYKANLEKLASGDVIRVAEVVRDLWRRERERGLSAGEKRMLAKARQILVSELALAENTNEDKAEALLDEVLAS
>NZ_CP014485.1|WP_075986682.1|3192401_3192638_+|hypothetical-protein
MGIDHGVANLERHVTGTPSVAIKGNTRIGALEWRFRRSGHISGLDNNNANVLRRACGTRYSQVGAALRGKGNAYVTGS
>NZ_CP014485.1|WP_030307792.1|3193175_3193856_+|hypothetical-protein
MSSSLRRGALAAAAIAFSIASLASCAAGNNAETHQINPDNARATVGDIMVQNAVVVTQPDRESTGPAIVAATIFNNGTKDQTLDSVVVDGVNKKAELTAAQGNGKLTIPAGGRLIVGGEDNASAVLPSSRTAVLDGNAQAITFTFSRTGDVKLNTLVVPATSYFEKWGPSEMPSAPASGSPSPDTSASPGEGSETPADETGGPTEGAEGAEGAQGEAADGASHAGH
>NZ_CP014485.1|WP_008410337.1|3193943_3194624_-|response-regulator-transcription-factor
MTRVLVVEDEESFSDALSYMLRKEGFEVAIAATGPEGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGRSNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRGEPEEAVPQALEAGPVRMDVDRHVVTVSGGKVDLPLKEFDLLEMLLRNAGRVLTRMQLIDRVWGADYVGDTKTLDVHVKRLRAKIEPDPGAPRYLVTVRGLGYKFEP
>NZ_CP014485.1|WP_008410335.1|3194620_3195925_-|two-component-sensor-histidine-kinase
MDVNTAVAAVAAIAGVCTGVIAMLAFRWSERELRRPTRSSLHSTPVLPPGVDTVLSALRSSAVVLDEGDGVVKASSAAYALGLVRGGKLAVEPMLKMARDTRRDGEIRQAELDLPRRGAGRGDGLAVSARVAPLGSRLVLLLVEDLTEARRIEAVRRDFVANVSHELKTPVGALSLLSEAVRDAADDPEAVERFAGRMEIEATRLTSLVQELIDLSRVQNDDPMEDAEPVDVDELIAEAMDRSRQAAAHKQITMSWGGDIDLFVWGSRGALVGALGNLVENAVNYSPPRTRVGVAARRVAEPDGTYIDITVTDQGIGISEKDRERIFERFYRVDPARSRATGGTGLGLAIVKHVAASHGGEVTVWSSEGQGSTFTLRLPEAGATRDRRTRPKTRPRPATGGPDASGATAARTTGDVPVPLTAPPSVLPAPEVLP
>NZ_CP014485.1|WP_003949791.1|3196111_3196792_+|phosphate-signaling-complex-protein-PhoU
MRDAYHEELDSIGDSLVEMARLVGSAIGRATTAILDADLNLAESVIAGDQKIDDLQHDLEARAIALLARQQPVATDLRIVVTSLRMSADLERSGDLAKHVAKQARLRYPESPVPRDLHATLLEMGQLAQRLMAKAAEVIITKDVDLALQLETDDDEMDLLHRTLFQHLMDDRWKHGVETAVDVTLLGRYYERFADHAVSVANRVVYLVTGEHADGIQTPGVPVEGV
>NZ_CP014485.1|WP_003949789.1|3197422_3197746_+|multidrug-transporter
MTWVLLACAILAEVTATISLRLSEGFSKIAPSVVVVVGYVTAFTLLALVLKRGMAIGVAYGIWAAAGVALVALIGAAFLGDSLTPVQYGGLVLVAAGVVALEAGGAH
>NZ_CP014485.1|WP_061404502.1|3197735_3198299_+|TetR-family-transcriptional-regulator
MPTEPVADGRRARGEETRRRLLDATVRVIERDGVAGVTHRAVAAEAGVPKSVASYHYPAVDDLLTAALRDSSDAYARDLAALLPEGYGLGDLAAHLTACQEENRSRALAEYELYLQAARRPALRPAAARWTAVLAELAAPFTTDPAIVATLTATLDGLFLQALLRDEPVDTGRVEAAMRVVIEGAAR

Crispr_ID: NZ_CP014485_17

• CRISPR_ID: NZ_CP014485_17
• CRISPR_location: 3395117-3395633
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of NZ_CP014485_17

Consensus_repeat	Method
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	PILER-CR
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	CRISPRCasFinder
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	CRT

spacers of NZ_CP014485_17

>17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
TGCTGGAAGCGGGTGCAGTCGCAGCTGACCTG
>17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
TACGAACGGGCCGAGGCCCGCGCCGAGCGGTT
>17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
TCGGCGGCCTTGATGCCGGTGGAGGGGACGCC
>17.4|3395329|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
GTGTATGAGCTTCTTGGCCAAGGTGGGTTGCC
>17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
CCGGGCCGTCAGCCGGCGGGCACGAGAGCGGC
>17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
GCGTTCGGGGCGCCGTCGTACCCGATGGCCGG
>17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
TGCCAGCCGGCGACGAACCCGGCCCAGGTCAG
>17.8|3395573|32|NZ_CP014485|CRISPRCasFinder,CRT
ACCATCGTGGTCCTGCCTCGGGCGGTCGGCGG

CRISPR arrays and Neighbor proteins around NZ_CP014485_17

CRISPR arrays

The CRISPR arrays of NZ_CP014485_17

>merge|NZ_CP014485|17|3395117-3395633|PILER-CR,CRISPRCasFinder,CRT
GTGGTCCCCGCGAGGGCGGGGGTGTTCCGTGCTGGAAGCGGGTGCAGTCGCAGCTGACCTGGTGGTCCCCGCGAGGGCGGGGGTGTTCCGTACGAACGGGCCGAGGCCCGCGCCGAGCGGTTGTGGTCCCCGCGAGGGCGGGGGTGTTCCGTCGGCGGCCTTGATGCCGGTGGAGGGGACGCCGTGGTCCCCGCGAGGGCGGGGGTGTTCCGGTGTATGAGCTTCTTGGCCAAGGTGGGTTGCCGTGGTCCCCGCGAGGGCGGGGGTGTTCCGCCGGGCCGTCAGCCGGCGGGCACGAGAGCGGCGTGGTCCCCGCGAGGGCGGGGGTGTTCCGGCGTTCGGGGCGCCGTCGTACCCGATGGCCGGGTGGTCCCCGCGAGGGCGGGGGTGTTCCGTGCCAGCCGGCGACGAACCCGGCCCAGGTCAGGTGGTCCCCGCGAGGGCGGGGGTGTTCCGACCATCGTGGTCCTGCCTCGGGCGGTCGGCGGGTGGCCCCCGCAAGGGCGGGGTGGCCCCA

>NZ_CP014485|17|5|3395117-3395572|PILER-CR
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TGCTGGAAGCGGGTGCAGTCGCAGCTGACCTG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TACGAACGGGCCGAGGCCCGCGCCGAGCGGTT
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TCGGCGGCCTTGATGCCGGTGGAGGGGACGCC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	GTGTATGAGCTTCTTGGCCAAGGTGGGTTGCC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	CCGGGCCGTCAGCCGGCGGGCACGAGAGCGGC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	GCGTTCGGGGCGCCGTCGTACCCGATGGCCGG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TGCCAGCCGGCGACGAACCCGGCCCAGGTCAG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG

>NZ_CP014485|17|13|3395117-3395633|CRISPRCasFinder
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TGCTGGAAGCGGGTGCAGTCGCAGCTGACCTG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TACGAACGGGCCGAGGCCCGCGCCGAGCGGTT
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TCGGCGGCCTTGATGCCGGTGGAGGGGACGCC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	GTGTATGAGCTTCTTGGCCAAGGTGGGTTGCC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	CCGGGCCGTCAGCCGGCGGGCACGAGAGCGGC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	GCGTTCGGGGCGCCGTCGTACCCGATGGCCGG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TGCCAGCCGGCGACGAACCCGGCCCAGGTCAG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	ACCATCGTGGTCCTGCCTCGGGCGGTCGGCGG
GTGGCCCCCGCAAGGGCGGGGTGGCCCCA

>NZ_CP014485|17|1|3395117-3395633|CRT
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TGCTGGAAGCGGGTGCAGTCGCAGCTGACCTG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TACGAACGGGCCGAGGCCCGCGCCGAGCGGTT
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TCGGCGGCCTTGATGCCGGTGGAGGGGACGCC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	GTGTATGAGCTTCTTGGCCAAGGTGGGTTGCC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	CCGGGCCGTCAGCCGGCGGGCACGAGAGCGGC
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	GCGTTCGGGGCGCCGTCGTACCCGATGGCCGG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	TGCCAGCCGGCGACGAACCCGGCCCAGGTCAG
GTGGTCCCCGCGAGGGCGGGGGTGTTCCG	ACCATCGTGGTCCTGCCTCGGGCGGTCGGCGG
GTGGCCCCCGCAAGGGCGGGGTGGCCCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003949595.1|3390929_3391337_+|RidA-family-protein	unknown	unknown	gnl|CDD|223329
NZ_CP014485.1|WP_061404554.1|3404474_3407486_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238119
NZ_CP014485.1|WP_061404549.1|3392048_3392624_-|heme-binding-protein	unknown	unknown	gnl|CDD|377163
NZ_CP014485.1|WP_061404553.1|3400163_3401435_+|methyltransferase	unknown	unknown	gnl|CDD|275041
NZ_CP014485.1|WP_018470313.1|3394319_3394979_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014485.1|WP_061404551.1|3396396_3397749_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_031178664.1|3402231_3403812_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|270371
NZ_CP014485.1|WP_026235287.1|3388122_3388311_-|hypothetical-protein	unknown	unknown	gnl|CDD|373048
NZ_CP014485.1|WP_003949585.1|3398667_3398886_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008413798.1|3393039_3394311_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP014485.1|WP_008413778.1|3403830_3404385_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003949596.1|3390377_3390758_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_CP014485.1|WP_010644052.1|3398473_3398671_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404552.1|3399015_3399273_+|putative-ATP-grasp-modified-RiPP	unknown	unknown	gnl|CDD|275039
NZ_CP014485.1|WP_061404547.1|3387168_3388119_-|hypothetical-protein	unknown	unknown	gnl|CDD|275040
NZ_CP014485.1|WP_018893691.1|3391378_3391999_-|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|223738
NZ_CP014485.1|WP_031178665.1|3401447_3402002_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404548.1|3389681_3390374_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_015507478.1|3388503_3389445_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP014485.1|WP_061404550.1|3395773_3396316_-|flavoprotein	unknown	unknown	gnl|CDD|235513

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003949595.1|3390929_3391337_+|RidA-family-protein	gnl|CDD|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	3.61696e-22
NZ_CP014485.1|WP_061404554.1|3404474_3407486_-|VWA-domain-containing-protein	gnl|CDD|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	3.42689e-09
NZ_CP014485.1|WP_061404549.1|3392048_3392624_-|heme-binding-protein	gnl|CDD|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	1.61573e-21
NZ_CP014485.1|WP_018470313.1|3394319_3394979_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.15646e-69
NZ_CP014485.1|WP_031178664.1|3402231_3403812_+|substrate-binding-domain-containing-protein	gnl|CDD|270371	cd13653, PBP2_phosphate_like_1, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.58843e-40
NZ_CP014485.1|WP_026235287.1|3388122_3388311_-|hypothetical-protein	gnl|CDD|373048	pfam14404, Strep_pep, Ribosomally synthesized peptide in Streptomyces species. A ribosomally synthesized peptide related to microviridin and marinostatin, usually in the gene neighborhood of one or more RimK-like ATP-grasp. The gene-context suggests that it is further modified by the ATP-grasp. The peptide is predicted to function in a defensive or developmental role, or as an antibiotic.	1.21507e-25
NZ_CP014485.1|WP_008413798.1|3393039_3394311_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.9229e-50
NZ_CP014485.1|WP_003949596.1|3390377_3390758_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	6.12361e-31
NZ_CP014485.1|WP_061404553.1|3400163_3401435_+|methyltransferase	gnl|CDD|275041	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system. Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).	2.61826e-164
NZ_CP014485.1|WP_061404552.1|3399015_3399273_+|putative-ATP-grasp-modified-RiPP	gnl|CDD|275039	TIGR04186, conserved_hypothetical_protein, putative ATP-grasp target RiPP. A RiPP is a ribosomally produced, post-translationally modified peptide. This family regularly occurs next to ATP-grasp enzymes related to those of microviridin maturation and next to a methyltransferase.	6.8476e-20
NZ_CP014485.1|WP_061404547.1|3387168_3388119_-|hypothetical-protein	gnl|CDD|275040	TIGR04187, conserved_hypothetical_protein, ATP-grasp ribosomal peptide maturase, SAV_5884 family. Members of this protein family are ATP-grasp ligase family enzymes that regularly occur in a contexts with a methyltransferase and a putative ribosomally translated post-translationally modified peptide precursor. Because of this conserved gene neighborhood and close sequence similarity to ATP-grasp enzymes from microviridin/marinostatin biosynthesis cassettes, this enzyme is suggested also to serve as a peptide maturase.	8.73153e-99
NZ_CP014485.1|WP_018893691.1|3391378_3391999_-|ankyrin-repeat-domain-containing-protein	gnl|CDD|223738	COG0666, Arp, FOG: Ankyrin repeat [General function prediction only].	7.2411e-14
NZ_CP014485.1|WP_015507478.1|3388503_3389445_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.85398e-08
NZ_CP014485.1|WP_061404550.1|3395773_3396316_-|flavoprotein	gnl|CDD|235513	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated.	7.4504e-07

Protein sequences

>NZ_CP014485.1|WP_018470313.1|3394319_3394979_+|response-regulator-transcription-factor
MPAPTDEPPTPAPVRLLLCDDHAVVRAGLRALLSSAPGIEVVAEAGSGEEALALTTLHHPDLVLMDLQLGEGIDGVETTRRLTTLPDHPPYVLVLTTYDTDADITRAVEAGATGYLLKAERPEELFTAIRAAASGRTALSPPVAQRVMTHLRNPQPELTPRERDILRHLTQGLGNREIARALFISEATVKTHLGRIYQKLGVETRAGAVAVGKERRLLG
>NZ_CP014485.1|WP_008413798.1|3393039_3394311_+|sensor-histidine-kinase
MRHPDDDLQPPPSPGAPTSGAFAPGAQTRDDRWLSALLTTAFVVLLAGALLRYVLKHGDSDRLPWIVGLSVVLAVVQVAGQARPGSRRAGRVRLAVVVACWVVVVLLAPSFAWCAVPLIHTALRLLPTRSAVALVTALATLVVLAELRLADGFDPNHLLLPPVVAALATGVFVYLTREATRRQHLIDDLVRTRRELAATERREGTLAERQRLSREIHDSLAQGLSSQNMLLQAADRQWDTDPQAARTHLRTAASIAAHGLTEARRLVHDLAPADLAEGAGLAQALATLAARESRDGLTVRFHAEGPDTHLPDQVASALLRTAQGALANIREHSGARTAALTLTCLDDTVALDVADDGRGFPAPGPGGARDPLGDPDPLRGHGLPAIRARLRQLGGTLAIESTPGEGAVLTATIPLTPATPPAP
>NZ_CP014485.1|WP_061404549.1|3392048_3392624_-|heme-binding-protein
MSLSTAFRSTRTRVLTGSAVVVALGAGVFGTVSASADTAPAAKPAAAQAAADASGRNVTQTSHLTIAAATKAAQAALDAAGKEKQKVSVAVVDRDGRALVTLRGDGAGPQSYEAAQEKAFTAVSWNAPTSELVKRLDSAPTLKDIPGTLFLAGGAPVTVMGAPVAGIGVAGAPSGDLDEKFAKAGVTALFR
>NZ_CP014485.1|WP_018893691.1|3391378_3391999_-|ankyrin-repeat-domain-containing-protein
MSRQEQKKAEARLIEAAGAGDAEGVKAALAAGARTEVSDASGRTPLLLASLGDHVAAARALVEAGADPDAQDDRDDSAWLVTGVTGSVEMMRTLLPAEPDQTLRNRFGGTALIPAAERGHVPYIRAALREASMEVDHVNGLGWTALLEAVILGDGGADHQETVRLLLAAGATPDLADRDGVTPREHAERRGFDRMAELLRKAEAAG
>NZ_CP014485.1|WP_003949595.1|3390929_3391337_+|RidA-family-protein
MAITLVDPEGLPKVGAYRQVAVATGSRLVFVAGQVAWDADGATVGAGDLAAQVERCYLNVHTALTAAGGTFADVAKLTVYVVDWTPDKMPHFLDGVARATARLGETPAAPGTLVGVAALDVPEHLVEVEATAVLD
>NZ_CP014485.1|WP_003949596.1|3390377_3390758_-|helix-turn-helix-transcriptional-regulator
MVTKQLSGTPEDADLSRADSLAREIFSEVANKWALLIIDALGESTVRFSEIRDRVEGISHKMLTQNLRMLERNGLVERYVHPTVPPRVDYTLTEPGLALRETTHLMCAWTQRYLGHIEGARGRFEG
>NZ_CP014485.1|WP_061404548.1|3389681_3390374_+|hypothetical-protein
MTEQRQQDNRPPTPSRRSQRRQTVAELRSQGRAGPGLRDVLPGFLGMVLVTAGPVIGLAWLYRAYGLGALLLGALLLAAATLIGVPWRRAVVRRRGGRYTPAELAVLDDHGLAVAAERILRRDGWHVLPMPDDGRPRLYARDRRDRRLDVSFRPVEGGPDAAEPPGGPATLREPGGPADDRVIRVVISMGTYSPAEIEWASRPGGDHLVDGRQLQQWASGTSLDALGLLT
>NZ_CP014485.1|WP_015507478.1|3388503_3389445_+|helix-turn-helix-transcriptional-regulator
MPAPKSVDPTASLAALLGARIRRLRRAKGWSQTELAAKGATSQGRLAQMELGRETPSQTVCQLLDQALDADGELLALWAHIERTPYPDWSRAFMRFEQRATRMRKYMAATVPGLLQTESYVRALLAAARPSVGGALESLVRARLERRLLLTGESPPYFWAILDESVLRRPIGQPEVMREQLTYLLHMQETERVSLQVLPFSAGVHPALGGSVTVLSFDRRPDVAYLESSHSGELIDDPEAAAGYGLAFDQLHAQALSPHASAAMIRNVLEGSYGVTRVSRRRRRSVAQEQLQQHAGWGLRRGPRRPARPGSDT
>NZ_CP014485.1|WP_026235287.1|3388122_3388311_-|hypothetical-protein
MTPFALQYARPQTGEPAAPYAFDQAEQVNVLAGGGYAAEDTALLARLGSTASTAGSKTHWDD
>NZ_CP014485.1|WP_061404547.1|3387168_3388119_-|hypothetical-protein
MTVLVLTCEEDVTADAVVLQLRRRGVPVLRLDPAEFPGRVDLAVRVTPDGQVTGHLATPGGRVALEEIRSVWVRRPGTPGAHVSAEQRAWITLECERALWGALRATGARWMNDPDALERSRHKLWQLATAARAGLRVPDTLVTTDPDEAARFQKTYADAGSGLVVKSVTGRHPQNPPLILPTAAVPPDADFTGVAACATCLQQRVPKRTDLRLTVVGDRYFPAYVTPRTPTLDWRFLPADASTWVAGKVDGALRAAVRRYLQEAQLAYAAFDFAIDEQGDPWFLEANAGGQFLFAEIETGMPMTEAIAAWLAIRRE
>NZ_CP014485.1|WP_061404550.1|3395773_3396316_-|flavoprotein
MTRPVLYLIATAAGPAQHVDVGIRAAQAAGWDTCLFLTPTAATWWADSMAELEGLTGHPVRHRYTLPGQSGGLPKADAMLVAPLTTTSACKWAAGITDTVALGVPAEAVHLGVPVVAAPFWSTALGAQPAVGRAVETLRGQGVRVVFTEGEPHLPKRGDAAGFGWGEALGEVERGVGGGG
>NZ_CP014485.1|WP_061404551.1|3396396_3397749_-|hypothetical-protein
MATRKRTPNPALADLLDQARWTRTQLAQQVNRLGPQAGLHLTYDRTAVAHWIAGTPPKPAVRPLILEALSARLGRPVTHEEAGLVPASSTEGARSVDTVEELIDLGRADMDPSRRKLLATATLFSAALCVPAFQQTARAADGTASPAKAISRIGPSQVTAVRAMTERVADILDELGAGHARPMAAAFLVNTVGPWLRADATEPVRRDMLAAASDLTYLTGWMAMYEKAHGLGQTYYTKALKLADEAGDHATYCRTLRGMSLQASSLGHGRMALELADSAAEAAPSAGPRLVAFLRGQQAHAASMVGDRNQAHSRLREAESALARADNRRDAVGGYDQTAYLFHVSHVLMEEGDHAGSIKALKHSIRVQAPQERQGRVHAYATLAQRQLRHGHLDASCDSWGRFLDEYEHVASVRGDEHFATMRRDLAPHAKVRAVKELAGRAREVSAAKA
>NZ_CP014485.1|WP_010644052.1|3398473_3398671_+|hypothetical-protein
MNAYERPDTYERLGAPGCRQCEELRDEEVQARREFDHSRAVDCRVLLRRHPHHDSPAPPAPTAPR
>NZ_CP014485.1|WP_003949585.1|3398667_3398886_+|hypothetical-protein
MTEPPARLPHPRRHWTPGTCWRCEAREVPVLWLGPVQTSSGTGSFTACDPCVRRLETYVRRELALRDTAPAF
>NZ_CP014485.1|WP_061404552.1|3399015_3399273_+|putative-ATP-grasp-modified-RiPP
MPITSPRTARPWGAARLAPYPTTTHVPYCKTEIDPLTQLGVALDRHGRVVEMGKHGTSTGTETNTTTSSDGQNNDQGHDQDSDKD
>NZ_CP014485.1|WP_061404553.1|3400163_3401435_+|methyltransferase
MGLAGTRHRPPDGRDARRPAGRRSHHTTDPTTTERHALAARLAQSGALHTPTWRRAVESVPREAFLHPGVFLPEPRGRWRPFLADRSPEAEWTRLAYSEQSLVTQLDGSLTPDQATTPEPVPGVPTSSSTEPALVLRMLESLEVAEGMRVLEIGTGTGYSSALLCHRLGEDAVTTVEVDPGVARRADDALEGIGVSTWTVTGDGLLGHPARAPYDRVIATCAVRRVPYTWVRQTRPGGVVLTTLGSWPHGAGLAKVTVGADGTAEGRIVGPASFMHARAQAQPPVTGDLAARAAYADSEREVCVPPTILEEWTPAFLAQLTVPDAQLVHARTAEGEQQRTYLFDPGRESFAEFAPGPRNAADWTVRQGGPVRLWDQVEEVLLAWRDAGSPGVDAVRLRVTETAHHYWLDGTSAPSLRWEHALR
>NZ_CP014485.1|WP_031178665.1|3401447_3402002_-|hypothetical-protein
MTMTDPYTCPSCSCGQNARTVAVGPPQLEDERPETARERVNRKWNEVLQETRVAQTGISILFGFLLSVAFTSLFGELAGLDRGIYVVTVVLAALATASLIAPVSLHRFLSGLRVKDELVDAAARLMVCGMVLLALTICGTLLLILRTAVPSLLAEVLVGGVMVWFGLCWYVLPWMIRRRAGRRR
>NZ_CP014485.1|WP_031178664.1|3402231_3403812_+|substrate-binding-domain-containing-protein
MEWVNAENVIAVGTFAVASSIAFGQWWYERMVPRRRRIGYRVQLDTAIGDDDGTGGGNTRLGLFDEADGMDEASVVLLRIENDGALSVSIGDYTSGGLHGMTATFDGREVHGVAVTVGPGSGALMSHFTPAHGLEYSGSSLRIPRVPLNKGEYFKLLVLLSGGTVGSKVTVSGGVQDGDVHPNESLTPDEKPPVFSRPARLTSMAFLVGIALLAGLIVTGGERPPPMGCATGSLEVTGSTAFAPVAEELAETYMEQCPGSRITVAAHGSTTGLRELAERGAAAKDGAPDLVALSDGPAPEGQETGDAGQDGGEAGEGGGLAGTRLAVSVFTLLAHADVPVRNLPLADLRRIYAGEVTDWREVGADRSLPIVLVGRGAASGTRDVLQRRLLEGAFEPPASSRDCSRKDNPKASVIRCELDTTDQVIATVARVPGALGYSELRTTSTLEGVRRLSLDGRRPSLDGAGHDAYPYREIEYAYTYGRPPADSLAAGFLAFTTRGPGQDVVRTHGHLPCGTPEGLRVCGAAD
>NZ_CP014485.1|WP_008413778.1|3403830_3404385_-|hypothetical-protein
MSNDSSAPLAENATWQALQATALGEVRRRAALVAAVVDVEPTTVDGAERLAWNDGGGQSAVWYFTADGRALLLTFDHEGSLNLYAEDDYALQVSLYRGVPEDLVALVRDRPENYESLNLTDPDSGATIHYAGGVFWFDGDSWHIADGLVAYCEQEKIELNGEAGFSYCLAPYHFGEEFPESGGK
>NZ_CP014485.1|WP_061404554.1|3404474_3407486_-|VWA-domain-containing-protein
MPAPTASTSVVTVKTGGDRNGDTSVAPLAGVRLGLYEAEDGGTPAFTCVSDADGDCSFVVTGTAVGGANEGRQFWVRQVAAPDGWFVNDTFRTGGTVTTPYRFQTPRLAAATTYSSTATGPGGFMVGSGGSNRTASTGTWQPSRVNPALPERCGLRVALIMDLSGSMSGSVPALKTAADTFVDALQGTPSSMARFTLSSYSPATRGGANAPGLVSVSTLADAAAFKRTYASWTNATAEGSTNWDRALYEPASATSQYDVAVVITDGMPTNYSIPGGPSGGASGSVTRFRELESGIASANALKNEGTRVLAVGVGEGTSGNAALNLASISGTEKYDGDNIATADYFQEADFAGAGAALRRLALAPCTPAVSVVKQIEAEDGTRTNAPAGWTFDAATQTPGVTVTSPRTTTGDGTGAFSFPLVYDGAETATLFVAERQQPGYQVVQQGGRNAVCTDRITERPVEVTDDPGGGPGFSVDVGVLASVTCSVVNKAPPELVPASLTVAKQWSVTTDGAPQVYPEGEQPRELRADLTLGDPTGNGSSPWEWGTVRDGYAAGEQVGVSEAPRFAAGVDCDLTGVDFDGAELDPAAPSTTVTLAAGANRHQVTNHVTCRTKLTLAKRVLGGDADPDDWTLRATGADGSLPGPVGTGGSAGTTGVPVTPEARYQLAESLTGTDPSLLNYRQVDNRTDYQSNPLSTGSMNCIAYDRDGTELLGWNDGINGGVNVPLGTHVTCTATNETVPLTLVKEVEGGTAVPEDWRITATPIEPDPAGVPAQTVTGAPGPAGAVITVRPGQAYRITEDGGPGGYELTSSTCRTDDGATGPRDLVLTVNSGQRGTCTLVNTAVPPSPATLTLVKEVDNRYGGTARPTDWTLYADGTGQSLEGVTGSPEVTGVQVDSGRYVLAERGPDGYDASAWSCGAEGEEPAPVADSAVDIAPGQEVTCTITNTHRKPGPKPTPDPSPGPHPPGPLPDTGLAGAWLGAGALLLVAAGAWLVFRVRRSARG

Crispr_ID: NZ_CP014485_18

• CRISPR_ID: NZ_CP014485_18
• CRISPR_location: 3485187-3485445
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP014485_18

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCTG	PILER-CR

spacers of NZ_CP014485_18

>18.1|3485211|56|NZ_CP014485|PILER-CR
TCCTGAGCCGGCAGGGGCGAGGCGGGCAGGACGGGGCGGAGCTTCCGGCCACACCC
>18.2|3485291|52|NZ_CP014485|PILER-CR
CCGTGGGCAACCGGGACGGGGGCGCAGCTCAGGTCGGGACGAAGCCCGCAGA
>18.3|3485367|55|NZ_CP014485|PILER-CR
ATCAGTGACCGGCTCGGTCGGGCTCCGGCAGGTCGGGGCGAAGCCCAACACAAAA

CRISPR arrays and Neighbor proteins around NZ_CP014485_18

CRISPR arrays

The CRISPR arrays of NZ_CP014485_18

>merge|NZ_CP014485|18|3485187-3485445|PILER-CR
CAGCCCGGCCGGCGACTGAGGCCATCCTGAGCCGGCAGGGGCGAGGCGGGCAGGACGGGGCGGAGCTTCCGGCCACACCCCAGCCTGGCCGGCGCTTGAGGCCACCGTGGGCAACCGGGACGGGGGCGCAGCTCAGGTCGGGACGAAGCCCGCAGACAGCCCGGCCGGCGCTTGAGGCCAATCAGTGACCGGCTCGGTCGGGCTCCGGCAGGTCGGGGCGAAGCCCAACACAAAACAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP014485|18|6|3485187-3485445|PILER-CR
CAGCCCGGCCGGCGACTGAGGCCA	TCCTGAGCCGGCAGGGGCGAGGCGGGCAGGACGGGGCGGAGCTTCCGGCCACACCC
CAGCCTGGCCGGCGCTTGAGGCCA	CCGTGGGCAACCGGGACGGGGGCGCAGCTCAGGTCGGGACGAAGCCCGCAGA
CAGCCCGGCCGGCGCTTGAGGCCA	ATCAGTGACCGGCTCGGTCGGGCTCCGGCAGGTCGGGGCGAAGCCCAACACAAAA
CAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_037638641.1|3485664_3487440_-|hypothetical-protein	unknown	unknown	gnl|CDD|320687
NZ_CP014485.1|WP_093559371.1|3495619_3496897_-|ATP-binding-protein	unknown	unknown	gnl|CDD|214640
NZ_CP014485.1|WP_061404570.1|3479111_3480467_+|histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP014485.1|WP_003949533.1|3475048_3475759_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140
NZ_CP014485.1|WP_061404569.1|3472802_3475052_-|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl|CDD|234921
NZ_CP014485.1|WP_003949525.1|3482350_3483844_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003949514.1|3501083_3501494_-|VOC-family-protein	unknown	unknown	gnl|CDD|319924
NZ_CP014485.1|WP_003949531.1|3476392_3476710_+|Lsr2-family-protein	unknown	unknown	gnl|CDD|378714
NZ_CP014485.1|WP_003949529.1|3478225_3479035_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NZ_CP014485.1|WP_030310101.1|3496893_3498456_-|ATP-binding-protein	unknown	unknown	gnl|CDD|213197
NZ_CP014485.1|WP_078842941.1|3494503_3495412_-|Dyp-type-peroxidase	unknown	unknown	gnl|CDD|367887
NZ_CP014485.1|WP_003949519.1|3491774_3492107_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NZ_CP014485.1|WP_061404571.1|3498639_3501030_-|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|223256
NZ_CP014485.1|WP_003949530.1|3477245_3478229_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP014485.1|WP_018894829.1|3480476_3481142_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014485.1|WP_003949517.1|3494146_3494491_+|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NZ_CP014485.1|WP_003949522.1|3487875_3489150_-|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl|CDD|234856
NZ_CP014485.1|WP_008409760.1|3475755_3476007_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|235659
NZ_CP014485.1|WP_049978357.1|3492210_3493869_-|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl|CDD|223732
NZ_CP014485.1|WP_049978031.1|3481353_3482256_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl|CDD|237571

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_003949519.1|3491774_3492107_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	4.6e-17	57.2	0.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_037638641.1|3485664_3487440_-|hypothetical-protein	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	1.75415e-06
NZ_CP014485.1|WP_093559371.1|3495619_3496897_-|ATP-binding-protein	gnl|CDD|214640	smart00382, AAA, ATPases associated with a variety of cellular activities. AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.	7.42081e-05
NZ_CP014485.1|WP_061404570.1|3479111_3480467_+|histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.47149e-38
NZ_CP014485.1|WP_003949533.1|3475048_3475759_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.30918e-143
NZ_CP014485.1|WP_061404569.1|3472802_3475052_-|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl|CDD|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP014485.1|WP_003949519.1|3491774_3492107_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	9.07104e-14
NZ_CP014485.1|WP_003949514.1|3501083_3501494_-|VOC-family-protein	gnl|CDD|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	8.59344e-39
NZ_CP014485.1|WP_003949531.1|3476392_3476710_+|Lsr2-family-protein	gnl|CDD|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	5.88457e-48
NZ_CP014485.1|WP_003949529.1|3478225_3479035_+|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	9.65729e-11
NZ_CP014485.1|WP_030310101.1|3496893_3498456_-|ATP-binding-protein	gnl|CDD|213197	cd03230, ABC_DR_subfamily_A, ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A. This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	0.00141001
NZ_CP014485.1|WP_078842941.1|3494503_3495412_-|Dyp-type-peroxidase	gnl|CDD|367887	pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.	7.90772e-92
NZ_CP014485.1|WP_061404571.1|3498639_3501030_-|excinuclease-ABC-subunit-UvrA	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NZ_CP014485.1|WP_003949530.1|3477245_3478229_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.86814e-97
NZ_CP014485.1|WP_018894829.1|3480476_3481142_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.82065e-60
NZ_CP014485.1|WP_003949517.1|3494146_3494491_+|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.37735e-08
NZ_CP014485.1|WP_003949522.1|3487875_3489150_-|phosphoribosylamine--glycine-ligase	gnl|CDD|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP014485.1|WP_008409760.1|3475755_3476007_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	2.46331e-40
NZ_CP014485.1|WP_049978357.1|3492210_3493869_-|SulP-family-inorganic-anion-transporter	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.84457e-118
NZ_CP014485.1|WP_049978031.1|3481353_3482256_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl|CDD|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0

Protein sequences

>NZ_CP014485.1|WP_003949525.1|3482350_3483844_-|hypothetical-protein
MGSGHIRRWESGAYAHAVSDPFGQGPVPWLRGSENYFDDTGQVVPWYVEHAPAPGASGPRIPPPRPGGGPRTADDVDQQIKGFASAGAVAPGESIDFHITVNPPQQFSVDVYRIGHYGGDGASKITTSPRLSGIVQPPPLTADRTVSCHHWWLSWRLQVPTLWSIGAYVAVLTTADGRYRSHVPFTVRDSHPADLLLVLPDVTWQAYNLYPEDGRTGASLYHAWDESGKLLGEEDAAVTLSFDRPYAGAGLPLHVGHAYDFIRWAERYGYDLAYADTRDLHSGRIDPTRYRGLVFPGHDEYWSVPMRNTVELARDHGTSLVFLSANTMYWKVELSPSASGVPDRMLICRKRRGPGRPALWREVERAEQQLLGIQYAGRVPEPHPMVVRNASHWLWEATGAHEGDELPGMVAGEADRYFPRTRLPEHDSRILLAHSPYRDHEGVKRHQETSLYRAPSGALVFASGTFAWSPALDRPGHVDERVQRATANLLDRICKRD
>NZ_CP014485.1|WP_049978031.1|3481353_3482256_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MSGFVEKPEPVEAPGLVHLHTGKVRDLYQNEAGDLVMVASDRISAYDWVLPTEIPDKGRVLTQLSLWWFDQLADLVPNHVLSTTLPEGAPADWKGRTLVCKSLEMAPVECVARGYLTGSGLVEYEESRTVCGLALPPGLVNGSELPAAIFTPATKAAVGDHDENVSYEEVARLVGPETAAELRQTTLAVYSRALDVARERGLILADTKFEFGHDADGTLILADEVLTPDSSRYWPADTWEPGRAQPSFDKQFVRDWLTSEASGWDRHAEQPPPALPEEVVDRTRAKYIEAYERLTGVSWG
>NZ_CP014485.1|WP_018894829.1|3480476_3481142_+|response-regulator-transcription-factor
MTEQSPEPPAPTGPAPSGGAPVRVLLADDEHLIRGAVAALLALEDDLVVVAEAATGPEALAMARAHRPDVAVLDLQMPGADGVAVATSLRDELPACRVMIVTGHGRPGNLKQALAAGVRGFVPKTVSAQRLAELVRSVHAGNRYIDPELAADAIAAGDSPLTAREAEVLELAADGAPVAEIAERAALSPGTVRNYLSSAVTKLGAENRHSAVRLARERGWV
>NZ_CP014485.1|WP_061404570.1|3479111_3480467_+|histidine-kinase
MTGTGDHEDAATYGATAQAAIRRPGRWWGRKGTAAKVESYTRISFHLFPVAQLVTALLSLTPVPARSALPVAGALLVHVVLGLRLTGQALDWVAGRRARPRRLLFAYMACGFAGAAIAALVLVKLPDDPPATYYTACVGTYVLFLAFSCGLGVLALRTHRQSLVAVAVATFGGWLLGSALLPAPAAAALALSTLLSAGGLTLASRFSIWLLQAVYELDEARHTRARLAVAEERLRFGRDLHDVLGRNLSVIALKSELAVRLARRGRPEAVEQMAEVQRIAQESQREVREVVRGYREADLYTELLGARGVLSAAGITCTVTGTPTGLPRPVQAALAWVVREAVTNVLRHGNAAHCRITLTVVPAGPRAEGRPAVAELTVENDGVPSASDGSSGGHGLAGLRERLAAEQGTLEAGPAGKSAFRLVARVPVPADEVAESGVPGETAERARQELE
>NZ_CP014485.1|WP_003949529.1|3478225_3479035_+|ABC-transporter-permease
MSAVTTPPAPAGQEQRTRPLGRLAALARAELALLVRSKGVMFAALFVPFVLPFSVAQTVDDDTLKGTGLTLGLVLLPGAIGFSLLFAVYSSLVTIYATRRDELVLKRLRTGELRDNEILAGTAVPSIIIGLAQSAVLIVAVTALLDIGAPKAPHLAVLGILVGIVLMVVLAALTSALSRTAESAQVMAMPVLLVLMLGSGMVVPLEVFPDSLASVCERLPLTGAMALIRGGWTGELSGGDILTAAVTSLAWIALSLFAVRRWFRWEPRR
>NZ_CP014485.1|WP_003949530.1|3477245_3478229_+|ABC-transporter-ATP-binding-protein
MNTEDHVIDVTDLRRVYGGGFEAVRGVSFTVGRGELFALLGTNGAGKTSTLEVLEGLARPASGRVRVLGHDPFGERDAVRPRIGVMLQDGGFPSELTVRETLRMWAGCTSGARPIGEALEMVGLGKRADVRVKVLSGGEKRRLDLALALLGRPEVLFLDEPTTGLDAEGRQDTWSLVRELRAEGTTVLLTTHYLEEAEALADRLAILHEGRIASEGTVEDVVSAQPSRITFDLPDGWFPGDLPPLDQLGVTGHSHDGRTVRLMTQNLQQAATSLLLWARDAGVSLGSLDVRAASLEEAFLHIAREADGRGDSATTAASLDPRKETAA
>NZ_CP014485.1|WP_003949531.1|3476392_3476710_+|Lsr2-family-protein
MAQRVVVTLFDDIDGGEASETVAFGLDGTSYEIDLNRTNAEKLRETLEPYLRAGRKRSASGRAYQRTSVAADPAAVRAWARSHQMDVPPRGRIPKRVYEAFEQAN
>NZ_CP014485.1|WP_008409760.1|3475755_3476007_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVDVMLKPEILDPQGQAVQRALPRLGFEGISDVRQGKRFELEVDGPVDDAALARIHELAETFLANTVIENFTVKVEEEK
>NZ_CP014485.1|WP_003949533.1|3475048_3475759_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MTAGPTPAARSNTRVGVVTFPGSLDDRDTQRAIRLAGAEAVPLWHKDKSLQQVDAVVLPGGFSYGDYLRAGAISRFSPLMEKVIDGARAGLPVLGICNGFQVLTEAHLLPGAMLGNDHLHFICRDQKLRVENTATAWTGDYVAGQEIHIPLKNMDGRYVADSRTLDMLEAEGRVAFRYLDVNPNGSLRDIAGITNEAGNVVGLMPHPEHAVEPLVGSGRTDGLPFFTSIIKKLVSA
>NZ_CP014485.1|WP_061404569.1|3472802_3475052_-|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSLDTVKHATDTPDTEQPWAELGLKEDEYARVREILGRRPTGAELAMYSVMWSEHCSYKSSKVHLRQFGEKAPQSDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTRRVLPGVVAGIGGYGNCLGLPNIGGEVVFDSCYQGNPLVNAGAIGVMRHEDIHLAKASGTGNKVILYGARTGGDGIGGASILASETFDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSGGMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLAICEKWDVIATVIGEVTDGDRLEIFWHGEKIVDVDPRTVAHDGPVYERPLARPEWQDALQADDAGKLPRPATGGELKEQVLALLSSPNQASKSWITSQYDHFVQGNTVLAQPEDAGMIRVDEESGLGVAIATDGNGRFAKLDPYHGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAIRGLADACQILGTPVTGGNVSLYNQTGDVAIHPTPVVAVLGVIDDVARRTPVAFAEEGQLLYLLGETREEFGGSAWSQVVHDHLGGLPPRVDLERERLLADILISASRDGMVDAAHDLSDGGLVQAVAESCLRGQKGARLVVPDELDAFTFLFSESAGRVVVSVPRSEELRFTDMCGARGLPATRIGVVDGDALEVQGEFTLSLREVREAHEGTIEALMA
>NZ_CP014485.1|WP_037638641.1|3485664_3487440_-|hypothetical-protein
MARAGAVAVLRVRGRAVALALLPAALAVVLLAGAPTGVLTGPVWDAARALVSAVAVLVLLAAAGLALAVARARPAVSPTVPVSEDSAPDLHRLVRDLADRLEVPAPSAIALTPDCDSWLEDRSHPALGADAVRPAHGQEPPAPVLVIGSPFLWWMRVAELRAVLAPVVAGTGPSAQPDIIAARRFVRGLDAAAALGTEPGRGPLARLVLGGTARLARLLLHACREEAAEMERAVAATSSERAKAVDYGLRIAAQEQVGLAYAGWDRLLNRVALPAWRIGRWPARLDAGVVAALTELSRRDRLADDFTTRLGERPACDLLEEPGTIDESTSLLAARLFHGEPAGSEPQWLPVDWEGYADEVVDRTWRTEAARLHRVLDGLGVPASEPGGATLARVLEHLAVPAGAPAAEPGGLPELTEAELATASDDELALRTGVDIGGEATGRAATVPQPGGEVRRRVAERAEELAEALAAEVARDEARVPAGVPAPVGQGADETLSAGGRLPLCPLQPPRTGRELLAGHVAAMVCCSAMDTAGALPGLDWLDGPVLLVQGRRASDLAVRVTALVDQGDGGPLLTWVHQTGIRPDKPVRLV
>NZ_CP014485.1|WP_003949522.1|3487875_3489150_-|phosphoribosylamine--glycine-ligase
MKVLVIGSGAREHALCRSLSLDPDVTALYCAPGNAGIAEVAELHPVDALDGAAVARLATGLGADLVVVGPEAPLVAGVADAVRVAGIDCFGPSAEAARLEGSKAFAKDVMAGAGVPTARSYVCTTAAEIDTALDAFGAPYVVKDDGLAAGKGVVVTEDVDEAREHALNCVSAGGGRVVVEEFLDGPEVSLFAVTDGRTVVPLQPAQDFKRALDGDQGPNTGGMGAYSPLPWADPKLVDEVLETVLQPTVDELRRRGTPFSGLLYAGLAITSRGIRVIEFNARFGDPETQVVLARLRTPLAGVLRAAADGTLAALPPLRWSEEAAVTVVVASHNYPGTPRTGDPVEGLAEVAELDAPAAYVLHAGTRQDGDAVLSAGGRVLSVTATGADLTEARDRAYTAVARIRLDGSQHRSDIAARVAVEERG
>NZ_CP014485.1|WP_003949519.1|3491774_3492107_-|helix-turn-helix-transcriptional-regulator
MSTPLYQLKAEFFKTLGHPVRIRVLELLSRREHAVSELLSDIGVEPAHLSQQLAVLRRANLVVPRREGSAVHYSLTNPDVAELLRVARTILSGVLTDQAELLAGLRADES
>NZ_CP014485.1|WP_049978357.1|3492210_3493869_-|SulP-family-inorganic-anion-transporter
MRSLLPTRADFAAMTRDPRRDLLAGLTVAIVALPLALGFGVSSGLGAEAGLATAVVAGALAALFGGSSLQVSGPTGAMTVVLVPIVAQYGPGGVLTVGLLAGVLLLALAVLKAGRYMRYVPAPVVEGFTLGIACVIGLQQVPNALGVTAPEGDSVLMVTWRAVEEFVRTPNWTATGLALGVAAVMLLGARWRPAVPFSIVAVVAATAAAQFFHLDGAAPIGALPSGLPAPSLDFLELSALGSLLAPALAVAALAALESLLSATVADGMTTGQKHDPDRELFGQGVANLAAPLFGGVPATAAIARTAVNVRSGAGSRLAALTHAAVLAVIVFAAAPLVSKIPLAALAGVLIATAVRMVEAGALRAMVRSTRSDAVVLVLTAVATLVLDLVLAVVIGLVVAGALALRAVAVQARIDRTDAPSEPPAVHGDAEHVPPSEHIATYRVDGPLFFAGAHRVLLELSEVASVRVVILRMARVTTMDATGALALKEAVEDLSRRGIAVLACGIRPAHRRTLASVGALEALRDREYATGPEALAAAHAHLGRTGPLPAGTA
>NZ_CP014485.1|WP_003949517.1|3494146_3494491_+|nuclear-transport-factor-2-family-protein
MASTEQVAERFHAALTAADADGLRGVLADEVTFEGPVATASGVAECVAGLVEMGKMISGDHVEVRLADGGNVLTWSTVRAGGGPGRPTVTWLRVDGERITAIRTVFDARGTGGR
>NZ_CP014485.1|WP_078842941.1|3494503_3495412_-|Dyp-type-peroxidase
MDAPLSAAAGFLVLVVKDGEEAVATVRSVVAGTDDLIKDITIRANGAMFTCNVGISHHGWPRLTGKPPPKELRPFREIKGEKHTAVATPGDLLYHLRAASPDLIVEFEKILLEAFGDSVTAVDDVTGFRYFDGRDLLEFADGTANPDGAALPAATLVGDEDPAYAGGSYVVVQKYLHDLSAWRAQTTGTQEEIIGRTKFDNVEKPDATEGQKSHKTLCTIQDADGEHDILRDNMPFAHPGTGEYGTYFIGYSRHLWVTEKMLERMFLGDPPPLHDRILDYSRAVTGATFFCPARAFLAALGD
>NZ_CP014485.1|WP_093559371.1|3495619_3496897_-|ATP-binding-protein
MSAGGLLPAQRSWVAQVCERLTDGQTVIVRGIPGSGKTVLLQAVARELGPTGVLTFGRDYTPDNQADRTATFQEGVLHSLSRYGSAQLLFDDYAHALRNPEGLRLQRQLLQLLVDGEYALDMGALLTGRWGRSMHLVSRGSPLVARARVVALPHPGSADFEAVGCAGSAEAAEAVGGNAALLAKVVPVLGRAALHQVRDSAQALVAKWVEDVPWEAVAWIKGVVRDGPAALPEDDSALEALAPLLVPAARQPDGLPRYGVVEALRTDEGRAALDGRAPTWPSRRQDSVKAFCAYLSGVPEAVWVDRYMAVKPADLLRFVQEVRGACSTRLRLLVAKNRNDMSFTEAEAAAFARHDCTVRVMLPGDRRLLHDRQLVFLGSLEGGVVLPTARVLMGQDLPGSAVAVRARNLDRKLILNVWERARPVS
>NZ_CP014485.1|WP_030310101.1|3496893_3498456_-|ATP-binding-protein
MAGTHNQQVLAEHKARFENRVSGGRQFNKLLREMGAEPNRFVEDPRDGRRWWIYITMPENVRDTFDLHLEVLCLSASYDRVEPRTLDTIAERLRKGEARLDPDFAILLTPDAGAENLVRRRRGQLPILTIDSSELLGHGARIGLRQRIARIMVTQDHYDLTKPITEPAAFYGRRTEVRDIDFALDRGQSVGIFGLRKAGKTSLLNFVENHRADKDRPVVRLDISGLTAEMFQLNLLQKCHELLRAGGAPAPRLATLTRDGRPNTAASLSTYWLNDLDALLDGLPGRLELFVDEIDQAWPGRSNLEEDEARALMRCLIQLRGVVQRREAGGKEGIGLVCAGVDPAIFERPLLDGKDNLLYKFVRLSFLSPMKKDEMQEMVRSLGKRMGLRYRDHETIDFLYHEFGGHPLLTRKACSAATRKRPTDEIPWHVTLEALREALEQRGPNTPRTEVSDVLDSFTDWFGDEAAMLPLLWSKDENEQRDAREWAESEPEMAAHLVLYGITDEKWAPRINAMRDLVLK
>NZ_CP014485.1|WP_061404571.1|3498639_3501030_-|excinuclease-ABC-subunit-UvrA
MTRATRQDAPSAAPHAADHHDLIRVHGARENNLKDVSIEIPKRRLTVFTGVSGSGKSSLVFDTIAAESQRLINETYSAFLQGFMPTLARPEVDVLEGLTTAIIVDQQRLGADPRSTVGTATDANAMLRILFSRLGDPHIGSPNAYSFNVPSVRAHGAITVERGNAKTVRQSFTRTGGMCPHCEGRGTVSDIDLTQLYDDSKSISEGAFTIPGWKSDSWWTVRLYADSGFLDPDKPIRDFTEQEMRDFLYREPTKVKVEGTNLTYEGLIPKIQKSFLSKDREGMQPHIRAFVDRAVTFTACPECGGTRLSEAARSSRIGELNIADACALQITDLADWVATLDEPSVAPLLAALRHTLDSFVEIGLGYLSLDRPAGTLSGGEAQRVKMIRHLGSSLTDVTYVFDEPTIGLHPHDIERMNGLLLRLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGTGGGTISFEGTVAGLRASDTLTGRHLDDRATLKKEVRKPTGTLEIRGADRHNLQDVDVDIPLGVLTVVTGVAGSGKSSLIHGSIPRSDEVVSVDQSPIRGSRRSNPATYTGLLDPIRKAFAKANGVKPALFSANSEGACPNCKGAGVVYTDLGMMAGVSATCEECDGKRFEASVLEHHLGGKDISEVLAMPVTEAEEFFREGEARTPAAHRVLTRLADVGLGYLTLGQPLTTLSGGERQRLKLATHMADKGGTYVLDEPTTGLHLADVDQLLALLDRLVDSGKSVIVIEHHQAVMAHADWIIDLGPGAGHDGGRVVFEGTPADLTENRGTVTGEHLAAYVGG
>NZ_CP014485.1|WP_003949514.1|3501083_3501494_-|VOC-family-protein
MHLTVHASFLPHNDPEAALAFYRDLLGLEVRDDVGYGGMRWITVGPPGGAGSAIVLLPPGADPGVTEDERRTIDAMMAKGTYGGILLATPDLTTTFEKLVAGDAEIVQEPTDQPYGVRDCAVRDPAGNLIRIQERR

Crispr_ID: NZ_CP014485_19

• CRISPR_ID: NZ_CP014485_19
• CRISPR_location: 3503335-3503423
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP014485_19

Consensus_repeat	Method
ACTGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP014485_19

>19.1|3503360|39|NZ_CP014485|CRISPRCasFinder
GTTGTTTGCCGGGCTCCGTCTCGACCGTGCCGGTCAAAG

CRISPR arrays and Neighbor proteins around NZ_CP014485_19

CRISPR arrays

The CRISPR arrays of NZ_CP014485_19

>merge|NZ_CP014485|19|3503335-3503423|CRISPRCasFinder
ACTGGCCTCAAGCGCCGGCCGGGCTGTTGTTTGCCGGGCTCCGTCTCGACCGTGCCGGTCAAAGACTGGCCTCAAACGCCGGCCGGGCT

>NZ_CP014485|19|14|3503335-3503423|CRISPRCasFinder
ACTGGCCTCAAGCGCCGGCCGGGCT	GTTGTTTGCCGGGCTCCGTCTCGACCGTGCCGGTCAAAG
ACTGGCCTCAAACGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_093559371.1|3495619_3496897_-|ATP-binding-protein	unknown	unknown	gnl|CDD|214640
NZ_CP014485.1|WP_003949514.1|3501083_3501494_-|VOC-family-protein	unknown	unknown	gnl|CDD|319924
NZ_CP014485.1|WP_003949517.1|3494146_3494491_+|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NZ_CP014485.1|WP_003949519.1|3491774_3492107_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NZ_CP014485.1|WP_037629784.1|3511590_3513174_+|M28-family-peptidase	unknown	unknown	gnl|CDD|349873
NZ_CP014485.1|WP_061404573.1|3508265_3509015_-|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP014485.1|WP_030310101.1|3496893_3498456_-|ATP-binding-protein	unknown	unknown	gnl|CDD|213197
NZ_CP014485.1|WP_008405038.1|3504082_3506119_+|TerD-family-protein	unknown	unknown	gnl|CDD|376767
NZ_CP014485.1|WP_049978354.1|3501522_3502044_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197666
NZ_CP014485.1|WP_061404574.1|3509900_3510713_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187632
NZ_CP014485.1|WP_008413369.1|3502420_3502990_-|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NZ_CP014485.1|WP_061404571.1|3498639_3501030_-|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|223256
NZ_CP014485.1|WP_061404575.1|3513784_3514459_+|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379163
NZ_CP014485.1|WP_003949500.1|3514540_3515176_-|uracil-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234653
NZ_CP014485.1|WP_078842941.1|3494503_3495412_-|Dyp-type-peroxidase	unknown	unknown	gnl|CDD|367887
NZ_CP014485.1|WP_061404572.1|3507597_3508092_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_031178382.1|3509169_3509670_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|238198
NZ_CP014485.1|WP_003949502.1|3513310_3513607_+|type-II-toxin-antitoxin-system-VapB-family-antitoxin	unknown	unknown	gnl|CDD|227737
NZ_CP014485.1|WP_049978357.1|3492210_3493869_-|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl|CDD|223732
NZ_CP014485.1|WP_008408647.1|3510776_3511370_+|(Fe-S)-cluster-assembly-protein	unknown	unknown	gnl|CDD|132296

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_003949519.1|3491774_3492107_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	4.6e-17	57.2	0.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_093559371.1|3495619_3496897_-|ATP-binding-protein	gnl|CDD|214640	smart00382, AAA, ATPases associated with a variety of cellular activities. AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.	7.42081e-05
NZ_CP014485.1|WP_003949514.1|3501083_3501494_-|VOC-family-protein	gnl|CDD|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	8.59344e-39
NZ_CP014485.1|WP_003949517.1|3494146_3494491_+|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.37735e-08
NZ_CP014485.1|WP_003949519.1|3491774_3492107_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	9.07104e-14
NZ_CP014485.1|WP_037629784.1|3511590_3513174_+|M28-family-peptidase	gnl|CDD|349873	cd03876, M28_SGAP_like, M28 Zn-peptidase Streptomyces griseus aminopeptidase and similar proteins. Peptidase family M28; Streptomyces griseus Aminopeptidase (SGAP, Leucine aminopeptidase (LAP), aminopeptidase S, Mername-AA022 peptidase) subfamily. SGAP is a di-zinc exopeptidase with high preference towards large hydrophobic amino-terminal residues, with Leu being the most efficiently cleaved. It can accommodate all except Pro and Glu residues in the P1' position. It is a monomeric (30 kDa), calcium-activated and calcium-stabilized enzyme; its activation by calcium correlates with substrate specificity and it has thermal stability only in the presence of calcium. Although SGAP contains a calcium binding site, it is not conserved in many members of this subfamily. SGAP is present in the extracellular fluid of S. griseus cultures.	4.08908e-114
NZ_CP014485.1|WP_061404573.1|3508265_3509015_-|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.44697e-19
NZ_CP014485.1|WP_030310101.1|3496893_3498456_-|ATP-binding-protein	gnl|CDD|213197	cd03230, ABC_DR_subfamily_A, ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A. This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	0.00141001
NZ_CP014485.1|WP_008405038.1|3504082_3506119_+|TerD-family-protein	gnl|CDD|376767	pfam02342, TerD, TerD domain. The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.	5.08229e-60
NZ_CP014485.1|WP_049978354.1|3501522_3502044_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.13457e-26
NZ_CP014485.1|WP_061404574.1|3509900_3510713_+|SDR-family-oxidoreductase	gnl|CDD|187632	cd05374, 17beta-HSD-like_SDR_c, 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. 17beta-hydroxysteroid dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	6.77071e-80
NZ_CP014485.1|WP_008413369.1|3502420_3502990_-|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	2.08203e-23
NZ_CP014485.1|WP_061404571.1|3498639_3501030_-|excinuclease-ABC-subunit-UvrA	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NZ_CP014485.1|WP_061404575.1|3513784_3514459_+|LytR-C-terminal-domain-containing-protein	gnl|CDD|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	5.00619e-10
NZ_CP014485.1|WP_003949500.1|3514540_3515176_-|uracil-phosphoribosyltransferase	gnl|CDD|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	1.47948e-115
NZ_CP014485.1|WP_078842941.1|3494503_3495412_-|Dyp-type-peroxidase	gnl|CDD|367887	pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.	7.90772e-92
NZ_CP014485.1|WP_031178382.1|3509169_3509670_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|238198	cd00321, SO_family_Moco, Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the terminal reaction in the oxidative degradation of the sulfur-containing amino acids cysteine and methionine. Assimilatory NRs catalyze the reduction of nitrate to nitrite which is subsequently converted to NH4+ by nitrite reductase. Common features of all known members of this family are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate.	0.000976309
NZ_CP014485.1|WP_003949502.1|3513310_3513607_+|type-II-toxin-antitoxin-system-VapB-family-antitoxin	gnl|CDD|227737	COG5450, COG5450, Transcription regulator of the Arc/MetJ class [Transcription].	4.34799e-08
NZ_CP014485.1|WP_049978357.1|3492210_3493869_-|SulP-family-inorganic-anion-transporter	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.84457e-118
NZ_CP014485.1|WP_008408647.1|3510776_3511370_+|(Fe-S)-cluster-assembly-protein	gnl|CDD|132296	TIGR03252, TIGR03252, uncharacterized HhH-GPD family protein. This model describes a small, well-conserved bacterial protein family. Its sequence largely consists of a domain, HhH-GPD, found in a variety of related base excision DNA repair enzymes (see pfam00730). [DNA metabolism, DNA replication, recombination, and repair].	1.04751e-94

Protein sequences

>NZ_CP014485.1|WP_008413369.1|3502420_3502990_-|restriction-endonuclease
MAAATGASATALWWLHHTDRLPRRGKPHPHEPTALRAASLAEVDALSWREFEHHVAALCRRDGCRDVVVTGGAGDLGADVTATLPDGRRLVIQCKHYAPHRYVPSGDMQKFLGTAWLHHRADVAVFAATCPFGKAALALAAEHRITAVHRDLLGLWNSGTPLTALLAVGGAGQGDAAHRRRWRETYGRG
>NZ_CP014485.1|WP_049978354.1|3501522_3502044_-|helix-turn-helix-transcriptional-regulator
MSTSPPPAPHLGDLALLRRVRDRIDREYARPLDVEALARGVNMSAGHLSRQFRLAYGEPPYSYLMTRRIERAMALLRRGDLSVTEVCFAVGCSSLGTFSSRFTELVGVPPSVFRERQDLAGQNIEGMPACVAKQVTRPVRRARPPRGSAPGGEAAGGGAEPVRNREARTGRPA
>NZ_CP014485.1|WP_003949514.1|3501083_3501494_-|VOC-family-protein
MHLTVHASFLPHNDPEAALAFYRDLLGLEVRDDVGYGGMRWITVGPPGGAGSAIVLLPPGADPGVTEDERRTIDAMMAKGTYGGILLATPDLTTTFEKLVAGDAEIVQEPTDQPYGVRDCAVRDPAGNLIRIQERR
>NZ_CP014485.1|WP_061404571.1|3498639_3501030_-|excinuclease-ABC-subunit-UvrA
MTRATRQDAPSAAPHAADHHDLIRVHGARENNLKDVSIEIPKRRLTVFTGVSGSGKSSLVFDTIAAESQRLINETYSAFLQGFMPTLARPEVDVLEGLTTAIIVDQQRLGADPRSTVGTATDANAMLRILFSRLGDPHIGSPNAYSFNVPSVRAHGAITVERGNAKTVRQSFTRTGGMCPHCEGRGTVSDIDLTQLYDDSKSISEGAFTIPGWKSDSWWTVRLYADSGFLDPDKPIRDFTEQEMRDFLYREPTKVKVEGTNLTYEGLIPKIQKSFLSKDREGMQPHIRAFVDRAVTFTACPECGGTRLSEAARSSRIGELNIADACALQITDLADWVATLDEPSVAPLLAALRHTLDSFVEIGLGYLSLDRPAGTLSGGEAQRVKMIRHLGSSLTDVTYVFDEPTIGLHPHDIERMNGLLLRLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGTGGGTISFEGTVAGLRASDTLTGRHLDDRATLKKEVRKPTGTLEIRGADRHNLQDVDVDIPLGVLTVVTGVAGSGKSSLIHGSIPRSDEVVSVDQSPIRGSRRSNPATYTGLLDPIRKAFAKANGVKPALFSANSEGACPNCKGAGVVYTDLGMMAGVSATCEECDGKRFEASVLEHHLGGKDISEVLAMPVTEAEEFFREGEARTPAAHRVLTRLADVGLGYLTLGQPLTTLSGGERQRLKLATHMADKGGTYVLDEPTTGLHLADVDQLLALLDRLVDSGKSVIVIEHHQAVMAHADWIIDLGPGAGHDGGRVVFEGTPADLTENRGTVTGEHLAAYVGG
>NZ_CP014485.1|WP_030310101.1|3496893_3498456_-|ATP-binding-protein
MAGTHNQQVLAEHKARFENRVSGGRQFNKLLREMGAEPNRFVEDPRDGRRWWIYITMPENVRDTFDLHLEVLCLSASYDRVEPRTLDTIAERLRKGEARLDPDFAILLTPDAGAENLVRRRRGQLPILTIDSSELLGHGARIGLRQRIARIMVTQDHYDLTKPITEPAAFYGRRTEVRDIDFALDRGQSVGIFGLRKAGKTSLLNFVENHRADKDRPVVRLDISGLTAEMFQLNLLQKCHELLRAGGAPAPRLATLTRDGRPNTAASLSTYWLNDLDALLDGLPGRLELFVDEIDQAWPGRSNLEEDEARALMRCLIQLRGVVQRREAGGKEGIGLVCAGVDPAIFERPLLDGKDNLLYKFVRLSFLSPMKKDEMQEMVRSLGKRMGLRYRDHETIDFLYHEFGGHPLLTRKACSAATRKRPTDEIPWHVTLEALREALEQRGPNTPRTEVSDVLDSFTDWFGDEAAMLPLLWSKDENEQRDAREWAESEPEMAAHLVLYGITDEKWAPRINAMRDLVLK
>NZ_CP014485.1|WP_093559371.1|3495619_3496897_-|ATP-binding-protein
MSAGGLLPAQRSWVAQVCERLTDGQTVIVRGIPGSGKTVLLQAVARELGPTGVLTFGRDYTPDNQADRTATFQEGVLHSLSRYGSAQLLFDDYAHALRNPEGLRLQRQLLQLLVDGEYALDMGALLTGRWGRSMHLVSRGSPLVARARVVALPHPGSADFEAVGCAGSAEAAEAVGGNAALLAKVVPVLGRAALHQVRDSAQALVAKWVEDVPWEAVAWIKGVVRDGPAALPEDDSALEALAPLLVPAARQPDGLPRYGVVEALRTDEGRAALDGRAPTWPSRRQDSVKAFCAYLSGVPEAVWVDRYMAVKPADLLRFVQEVRGACSTRLRLLVAKNRNDMSFTEAEAAAFARHDCTVRVMLPGDRRLLHDRQLVFLGSLEGGVVLPTARVLMGQDLPGSAVAVRARNLDRKLILNVWERARPVS
>NZ_CP014485.1|WP_078842941.1|3494503_3495412_-|Dyp-type-peroxidase
MDAPLSAAAGFLVLVVKDGEEAVATVRSVVAGTDDLIKDITIRANGAMFTCNVGISHHGWPRLTGKPPPKELRPFREIKGEKHTAVATPGDLLYHLRAASPDLIVEFEKILLEAFGDSVTAVDDVTGFRYFDGRDLLEFADGTANPDGAALPAATLVGDEDPAYAGGSYVVVQKYLHDLSAWRAQTTGTQEEIIGRTKFDNVEKPDATEGQKSHKTLCTIQDADGEHDILRDNMPFAHPGTGEYGTYFIGYSRHLWVTEKMLERMFLGDPPPLHDRILDYSRAVTGATFFCPARAFLAALGD
>NZ_CP014485.1|WP_003949517.1|3494146_3494491_+|nuclear-transport-factor-2-family-protein
MASTEQVAERFHAALTAADADGLRGVLADEVTFEGPVATASGVAECVAGLVEMGKMISGDHVEVRLADGGNVLTWSTVRAGGGPGRPTVTWLRVDGERITAIRTVFDARGTGGR
>NZ_CP014485.1|WP_049978357.1|3492210_3493869_-|SulP-family-inorganic-anion-transporter
MRSLLPTRADFAAMTRDPRRDLLAGLTVAIVALPLALGFGVSSGLGAEAGLATAVVAGALAALFGGSSLQVSGPTGAMTVVLVPIVAQYGPGGVLTVGLLAGVLLLALAVLKAGRYMRYVPAPVVEGFTLGIACVIGLQQVPNALGVTAPEGDSVLMVTWRAVEEFVRTPNWTATGLALGVAAVMLLGARWRPAVPFSIVAVVAATAAAQFFHLDGAAPIGALPSGLPAPSLDFLELSALGSLLAPALAVAALAALESLLSATVADGMTTGQKHDPDRELFGQGVANLAAPLFGGVPATAAIARTAVNVRSGAGSRLAALTHAAVLAVIVFAAAPLVSKIPLAALAGVLIATAVRMVEAGALRAMVRSTRSDAVVLVLTAVATLVLDLVLAVVIGLVVAGALALRAVAVQARIDRTDAPSEPPAVHGDAEHVPPSEHIATYRVDGPLFFAGAHRVLLELSEVASVRVVILRMARVTTMDATGALALKEAVEDLSRRGIAVLACGIRPAHRRTLASVGALEALRDREYATGPEALAAAHAHLGRTGPLPAGTA
>NZ_CP014485.1|WP_003949519.1|3491774_3492107_-|helix-turn-helix-transcriptional-regulator
MSTPLYQLKAEFFKTLGHPVRIRVLELLSRREHAVSELLSDIGVEPAHLSQQLAVLRRANLVVPRREGSAVHYSLTNPDVAELLRVARTILSGVLTDQAELLAGLRADES
>NZ_CP014485.1|WP_008405038.1|3504082_3506119_+|TerD-family-protein
MREMSKGANVALAALSEDTSAVVVGLSWSSPAGEGDADVSVLLLGPDGKVRHDGDFYFYNHPASPDGSVQLLGKTPAGNGSEDRVSLDLGAVPPGVERIVIAASQYGDGRFGDLDELRLTLADRSGEMLLGYAIEGATDERAFLFGELYLREGAWKFRAIGQGYASGLAGLATDFGIDVDDEGEGEEGAAPPEDAQASATAAPGSPEPSDPAPAPAPPVALPAQRPAPEPAAAKPVRRRPRTAKKKVTLPAARQRTLAENDAWRSARLFPAASLKSDRERETRSTSVLLAAMAQVPEFGRRLTAAFGAPAGRMETFTEVTLPHGETPRRPDGIIRVERAGKLWTALVETKTNGNPLRADQVQSYVDIAARRGYEAVITLSNDVALEGRPLVEVKMDRRRKHKVALWHLSWAEVAHQAQLLIRHEGVGNAAHAWLLQELLHYLQHDNSGCQGFQNMGPSWVQVRNGIDAETLCPGDARAVDVIESWERLVRQVCLRIGGELGRKAMPVQRGKRGADPAARRAALADRLCEDGRLTAELRVDGSPGVLALTADLRTGKLRTSVEVPVPEGGYPLSSAKRLLRMLAEAPADLHVETLVEEGNGPRSTLERLRPEPADLLPRNGERIMGFRLSLFKGMGTTRGSAASGFIRSVDEAVDHFHAQVVAHLPVPDSRPARRPVPA
>NZ_CP014485.1|WP_061404572.1|3507597_3508092_-|hypothetical-protein
MADVDPDTDARRDTGAHPAAEAVRFGPGPVLRLELTDHRDGLFDGAWWPYSHRVHIEIPRLIGGLAGHWGPVTRVGVDLETWGALPTRLVIDGRVVRIDGYPVADDTALVTRDDRALFSLLVVPPEAAPEAAVAAMARALDPRNTAAAGTILTETGVRPGHPRR
>NZ_CP014485.1|WP_061404573.1|3508265_3509015_-|sulfite-exporter-TauE/SafE-family-protein
MTLWEAVAVLLAGFAGGALNTAVGSGTLVTFPVLLATGLPPVTATVSNALGLIPGSLSGAYAYRRELAGQRRLLLSLCASAAAGGLVGAGLLMVLPPGVFATVVPVLVGLALLLIAVQPLLTRALRGRLTRPGGGLPLRIGLGLASVYGGYFSAGQGILYVALSGALLDAPLQRINALKNVLVAQVNAVAAGFFLIAADIDWPAALLIAAGATAGAPFGARAAQRLRPVALRVLILTVGTAGLLHMTLS
>NZ_CP014485.1|WP_031178382.1|3509169_3509670_-|molybdopterin-dependent-oxidoreductase
MSGASGTARTGRCVELCGETGEPARLTVAELAGGWPEQRAEVVFDCATSGPRHHTFTGPLLRDVLLGALPGAVPATRKDRAGRLLVVAGADGHRAVLAWAEVDEEFRYAPVLLAVRLDGALLDAPHLVVPADRCGARYVSAVTGVRLVRPGLPVAAGEERLVSGAG
>NZ_CP014485.1|WP_061404574.1|3509900_3510713_+|SDR-family-oxidoreductase
MDQAGRDGRTALVTGASSGIGAAVAALLVARGYRVLGTSRDPERVAEPVPGVTYLALDLADEASVRACAEAAGPVDVLVNNAGESQSGPLEELPPEALERLFRVNVLSAVRLTQLLLPAMRERRAGRIVMVGSMLASFPLAYRSSYVASKAALKGFADAARRELAPYGIRMSTVEPGSIATGISERRTEYVAANSPYRAEYATMLRHLNANEAAGIPAEKVAATVLRAVEDERPRPLYAVGSNAPFVFALRRLLPRAAVLRIVARRHGLG
>NZ_CP014485.1|WP_008408647.1|3510776_3511370_+|(Fe-S)-cluster-assembly-protein
MEKTLRLAQEPRADALLSRSPLADLVGMLLDQQVPMEWAFSGPYTIARRMGADDLDAHEIAAYDPDEFAALLSAKPAVHRYPGSMARRVQQLCQYLVDHYDGDAEALWRDVADGEELLGRLKALPGYGPQKAQIFLALLGKQLGVRPPGWREAAGVYGQEHAYRSVADITGPESLARVRAHKQEMKRAAKAARDDGS
>NZ_CP014485.1|WP_037629784.1|3511590_3513174_+|M28-family-peptidase
MAVVAATALATPLLLGAAPGHGHGHGPGHGHKPSTPGKDAAALARELVKESSAHDAHRHLRKLQSIADRNDGHRAAGSPGHEASAAYIEKLMKKAGYKVTRQTFSFTYTETLAQKLSVVEPGQRDVAVHAMTYTASTPEGGLQAALVDTPADADSTPGCTAADYSAEVEGAVALIERGGCSFAEKQAAAAEAGAVGAIIYNNTEGALSGTLGEAGAGRVPTGGVTQAEGKALAADAAKGAKVSLEIRQLQEERETDNLLAETRGGSADRTVMLGAHLDSVTEGAGINDNGSGSAGLVEVALNLADATNQNRPGKHGKAKEPRNKVRFAWWSAEENGLLGSEHYVGKLSEKQRGQIPAYLNFDMIASPNAAQFVFDGDDSDGVGEGPGPEGSAQIERDITAFLDRQGKPHEGTDFDGRSDYGPFVEAGIPAGGTFTGAEGLKTKEQAKRYGGTAGEAYDPCYHSACDDLKNISMKAFDTNIDVIAHAVGTYAHDLSSLGKPVKQKAAPEAQRHQGEGRAHGHHHGLTE
>NZ_CP014485.1|WP_003949502.1|3513310_3513607_+|type-II-toxin-antitoxin-system-VapB-family-antitoxin
MIFKRIGNGRPYPDHGRESTRQWADVAPRPVRLDQLVTTKGQLDLETLLAEDSTFYGDLFAHVVKWRGDLYLEDGLHRAVRAALQQRQVLHARVLELD
>NZ_CP014485.1|WP_061404575.1|3513784_3514459_+|LytR-C-terminal-domain-containing-protein
MGGKYRITGDKYPRMRRTGGRRKLVLAATGGVLALGLVGWGTFQLVDVFTGGSTATAAGGRNCPAPATSASPAKATPLPAPGRIKVNVLNATERSGLAKQTADALKKRGFAIGEVGNATEEYDKKVKGTVLLLGAADAVDGAFPVLATQVGGAKQKVEAPVKGEPAEAEGEADEAAKGPRKPNEVDLIIGDGFKKLAPEAAATGALKALNAPKPSPSPTAAGRC
>NZ_CP014485.1|WP_003949500.1|3514540_3515176_-|uracil-phosphoribosyltransferase
MRIHVVDHPLVAHKLTTLRDKRTDSPTFRRLADELVTLLAYEATRDVRTEQVDIDTPVARTTGVKLSYPRPLVVPILRAGLGMLDGMVRLLPTAEVGFLGMIRDESTLQASTYAARMPEDLTGRQVYVLDPMLATGGTLVAAIKEMIRRGADDITAVVLLAAPEGVEIMERELEGTPVTVVTASVDERLNENGYIVPGLGDAGDRMYGQAD

Crispr_ID: NZ_CP014485_20

• CRISPR_ID: NZ_CP014485_20
• CRISPR_location: 3734341-3734432
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_20

Consensus_repeat	Method
AATTCCAGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP014485_20

>20.1|3734370|34|NZ_CP014485|CRISPRCasFinder
TCGGTGACGCGCGCCGGGCAACGGCACCGCACCC

CRISPR arrays and Neighbor proteins around NZ_CP014485_20

CRISPR arrays

The CRISPR arrays of NZ_CP014485_20

>merge|NZ_CP014485|20|3734341-3734432|CRISPRCasFinder
AATTCCAGCCCGGCCGGCGCTTGAGGCCATCGGTGACGCGCGCCGGGCAACGGCACCGCACCCAATTCCAGCCCGGCCGGCGCTTGAGGCCA

>NZ_CP014485|20|15|3734341-3734432|CRISPRCasFinder
AATTCCAGCCCGGCCGGCGCTTGAGGCCA	TCGGTGACGCGCGCCGGGCAACGGCACCGCACCC
AATTCCAGCCCGGCCGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_018470204.1|3726876_3728703_-|acyl-CoA-dehydrogenase-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|173842
NZ_CP014485.1|WP_003949290.1|3731930_3734255_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP014485.1|WP_003949293.1|3728843_3729338_+|SseB-family-protein	unknown	unknown	gnl|CDD|377787
NZ_CP014485.1|WP_030307135.1|3737392_3738289_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP014485.1|WP_026282572.1|3729743_3730700_+|pirin-family-protein	unknown	unknown	gnl|CDD|224655
NZ_CP014485.1|WP_030310156.1|3722629_3723922_-|M18-family-aminopeptidase	unknown	unknown	gnl|CDD|235073
NZ_CP014485.1|WP_079076079.1|3741338_3743384_+|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|226361
NZ_CP014485.1|WP_061404621.1|3734595_3736380_+|aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775
NZ_CP014485.1|WP_003949285.1|3738388_3739045_-|HD-domain-containing-protein	unknown	unknown	gnl|CDD|188314
NZ_CP014485.1|WP_030307132.1|3739152_3739620_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404620.1|3725063_3726041_-|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176206
NZ_CP014485.1|WP_059214288.1|3726178_3726706_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|226489
NZ_CP014485.1|WP_003949279.1|3743506_3743791_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008414096.1|3736788_3737340_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP014485.1|WP_010644618.1|3730840_3731920_+|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
NZ_CP014485.1|WP_003949299.1|3722201_3722432_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003949283.1|3739774_3740170_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|133390
NZ_CP014485.1|WP_003949288.1|3736470_3736725_-|hypothetical-protein	unknown	unknown	gnl|CDD|274395
NZ_CP014485.1|WP_030307128.1|3740294_3741107_+|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270256
NZ_CP014485.1|WP_015507562.1|3724436_3725051_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_018470204.1|3726876_3728703_-|acyl-CoA-dehydrogenase-C-terminal-domain-containing-protein	gnl|CDD|173842	cd01153, ACAD_fadE5, Putative acyl-CoA dehydrogenases similar to fadE5. Putative acyl-CoA dehydrogenase (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	0
NZ_CP014485.1|WP_003949290.1|3731930_3734255_-|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	6.06901e-46
NZ_CP014485.1|WP_003949293.1|3728843_3729338_+|SseB-family-protein	gnl|CDD|377787	pfam07179, SseB, SseB protein N-terminal domain. This family consists of several SseB proteins which appear to be found exclusively in Enterobacteria. SseB is known to enhance serine-sensitivity in Escherichia coli and is part of the Salmonella pathogenicity island 2 (SPI-2) translocon. This entry contains the presumed N-terminal domain of SseB.	5.59412e-05
NZ_CP014485.1|WP_030307135.1|3737392_3738289_-|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	1.15131e-18
NZ_CP014485.1|WP_026282572.1|3729743_3730700_+|pirin-family-protein	gnl|CDD|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.74803e-66
NZ_CP014485.1|WP_030310156.1|3722629_3723922_-|M18-family-aminopeptidase	gnl|CDD|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
NZ_CP014485.1|WP_079076079.1|3741338_3743384_+|molybdate-ABC-transporter-permease-subunit	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	7.47145e-82
NZ_CP014485.1|WP_008414096.1|3736788_3737340_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.99052e-37
NZ_CP014485.1|WP_003949285.1|3738388_3739045_-|HD-domain-containing-protein	gnl|CDD|188314	TIGR03401, Uncharacterized_protein_YFL061W/YNL335W, HD domain protein, cyanamide hydratase family. Members of this protein family are known, so far, in the Ascomycota, a branch of the Fungi, and contain an HD domain (pfam01966), found typically in various metal-dependent phosphohydrolases. The only characterized member of this family, from the soil fungus Myrothecium verrucaria, is cyanamide hydratase (EC 4.2.1.69), a zinc-containing homohexamer that adds water to the fertilizer cyanamide (NCNH2), a nitrile compound, to produce urea (NH2-CO-NH2). Homologs are likely to be nitrile hydratases.	1.27503e-12
NZ_CP014485.1|WP_003949283.1|3739774_3740170_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	5.29234e-14
NZ_CP014485.1|WP_061404620.1|3725063_3726041_-|zinc-binding-dehydrogenase	gnl|CDD|176206	cd08244, MDR_enoyl_red, Possible enoyl reductase. Member identified as possible enoyl reductase of the MDR family. 2-enoyl thioester reductase (ETR) catalyzes the NADPH-dependent dependent conversion of trans-2-enoyl acyl carrier protein/coenzyme A (ACP/CoA) to acyl-(ACP/CoA) in fatty acid synthesis. 2-enoyl thioester reductase activity has been linked in Candida tropicalis as essential in maintaining mitiochondrial respiratory function. This ETR family is a part of the medium chain dehydrogenase/reductase family, but lack the zinc coordination sites characteristic of the alcohol dehydrogenases in this family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. Candida tropicalis enoyl thioester reductase (Etr1p) catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis. Etr1p forms homodimers, with each subunit containing a nucleotide-binding Rossmann fold domain and a catalytic domain.	2.24017e-90
NZ_CP014485.1|WP_059214288.1|3726178_3726706_+|GNAT-family-N-acetyltransferase	gnl|CDD|226489	COG3981, COG3981, Predicted acetyltransferase [General function prediction only].	4.70045e-45
NZ_CP014485.1|WP_010644618.1|3730840_3731920_+|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	9.01595e-44
NZ_CP014485.1|WP_003949288.1|3736470_3736725_-|hypothetical-protein	gnl|CDD|274395	TIGR03022, WbaP_sugtrans, Undecaprenyl-phosphate galactose phosphotransferase, WbaP. The WbaP (formerly RfbP) protein has been characterized as the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. This model includes the enterobacterial enzymes, where the function is presumed to be identical to the S. typhimurium enzyme as well as a somewhat broader group which are likely to catalyze the same or highly similar reactions based on a phylogenetic tree-building analysis of the broader sugar transferase family. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. The most likely heterogeneity would be in the precise nature of the sugar molecule transferred.	0.000292658
NZ_CP014485.1|WP_061404621.1|3734595_3736380_+|aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP014485.1|WP_030307128.1|3740294_3741107_+|molybdate-ABC-transporter-substrate-binding-protein	gnl|CDD|270256	cd13538, PBP2_ModA_like_1, Substrate binding domain of putative molybdate-binding protein;the type 2 periplasmic binding protein fold. This subfamily contains domains found in ModA proteins of putative ABC-type transporter. Molybdate transport system is comprised of a periplasmic binding protein, an integral membrane protein, and an energizer protein. These three proteins are coded by modA, modB, and modC genes, respectively. ModA proteins serve as initial receptors in the ABC transport of molybdate mostly in eubacteria and archaea. After binding molybdate with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ModA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.76688e-83

Protein sequences

>NZ_CP014485.1|WP_003949290.1|3731930_3734255_-|SpoIIE-family-protein-phosphatase
MRTEDSLPDVRDVLAAVATGLWRWDNARGVVTIDAEAARLLGLPEEAAVLPETVVRARFHPVDWNEINGVVSLALTEGTLAEVRLRVMDGEGRVLRTVRSRSKPERIGPERRDVLLTGTLQEASEPPAGARAAVTGDWRRSREAFLLDAGRALAEARSTDEVLRVAAGLSMPGFSPDGLAVFGVEGERLTVVGHHGQNSGDEEPFLDMTLETSYPAADVVRTGRAVYLSSPDEYRERYPLTWPLASRFDRQSWAFLPLVAGGRTIGAWMAAFTYRVYFTPDERSVLTTVARMLAQALSRAGDAESARELTDGLQRTMLPTLGPSVAGMSVAARYIPTGGGLQVGGDWYDMIPLPGAAHGEETGGTQRYAFVIGDVQGHDIRAAGLMGQLRIALRAYAAEGHRPDAVLARATRFLSGIMTSRIYGSSGGSNKGEDGALPVDEYADLRFATCLYIEADPSTGVLEVARAGHPDPVIRMPDGTVLLRPTTGGLPLGIDPDADYPITRIVLEPGETIMLCTDGMIETGGHDFATGFDRVRAVMERPGPPAADEADGQLHDPLSGDGLEDLADRLVQAVHGPSSYHRPGPLVDRREDDIAVLLMHRDLHATGGPVTAGRRTVVTIRQDEGERISEARQQLRAVMHDWADEDQVDSAVLLLSELLTNVLVHTDGDGLLAAELLGPPGSRRLRVEVSDPSDDLPHKRAPGELASSGRGLVLLDLLADSWGVDPQGSGKCIWFEMAEHEPGEKGEDAEEAEDAVPELDEAALDRLAEAAENL
>NZ_CP014485.1|WP_010644618.1|3730840_3731920_+|AI-2E-family-transporter
MLPEGAVRVAGWCVVLLLVTGVAWVAVWLCVLFRAAVIPVLLALLGTALLTPLHRRLLRMRVQRSLAAGLTCAAVLVVVGGATYIVVLALVDSGDQIVASAKLAAQDVAGFLGADEASLDDLASNARELFDRFGGPAASGVISGLGLVAQAGAMGVLAVLLVFFFIRDGDRVVGSLRTMAPGHVGEITEAIGRRAYRAVEGFMRGTTMIALIDGVLTTIGLLLLGVPGAAGLGALVFIGAYIPYLGAFVSGVLAVLVALADRGVVIAAWTLLVIFLVQMLEGNVLQPVIQSRTVQMHPAVVLVAITAGATVGGVIGVLLAVPATAAAFGIVAELRERYGGGSGATAAGAGPVGGEPGTP
>NZ_CP014485.1|WP_026282572.1|3729743_3730700_+|pirin-family-protein
MPAVTVENPLTLPRVVADADAVQRPVLAVTTAPSGFEGEGFPVRRAFAGINYKHLDPFIMMDQMGEVEYAAGEPKGTPWHPHRGFETVTYIIDGTFIHQDSNGGGGTITNGDTQWMTAGSGLLHIETPPESLVMSGGLFHGLQLWVNLPAKDKMKDPRYQDIRGGQVKLLTTGDGGALLRVIAGDFDGHEGPGITHTPITMIHASVRPGAEVTLPWREEYNGLAYVLAGRGTVGTDRRPVRTGQTAVFGAGSALTLRADESQDGHAPDLEVVLLGGKPLREPMAHYGPFVMNTRAELQQAFEDFQAGRLGTVPAVHGM
>NZ_CP014485.1|WP_003949293.1|3728843_3729338_+|SseB-family-protein
MYGYDQNAGAQQHYAPPQAGGYGDPQQAGGIGGYGQPQQPAYPEPSPPSLAEAVRAFTTGAMGGEDFQQVFATSKVYCPRGDNPGFLALHNTQQPVIPMFTSLKELRRYAGKDSKYFVITGAEVIDLLPTGYGFVLDMEGEHRMVFDAKAVEEMVDFAMRRMYG
>NZ_CP014485.1|WP_018470204.1|3726876_3728703_-|acyl-CoA-dehydrogenase-C-terminal-domain-containing-protein
MGHYKSNLRDIEFNLFEVLGRDKQYGTGPFAEMDVDTAKSILEEVARLAENDLADSFADADRNPPVFDPETNTAPLPESFKKSYKAFMESEYWRLGLPEEIGGTTAPRSLIWAHAELILGANPAIWMYSSGPAFAGILFEEGNEVQKKAAEIAVERQWGSTMVLTEPDAGSDVGAGRTKAVEQADGSWHIEGVKRFITSGEHDMSENILHYVLARPEGAGPGTKGLSLFLVPKYEFDWETGEIGARNGAYATNVEHKMGLKASNTCEMTFGDKHPAKGWLIGDKHDGIRQMFRIIEFARMMVGTKAIATLSTGYLNALEYAKERVQGPDLAQFMDKTAPKVTITHHPDVRRSLMTQKAYAEGMRTLVLYTAAVQDTIQVKEAAGEDATADHALNDLLLPIVKGYGSEKSYEQLAQSLQTFGGSGYLQEYPIEQYIRDAKIDTLYEGTTAIQGQDFFFRKIVRNQGAALNTLAGEIKGFLAEAQGGDALAGAREQLAKAAVELEALVGVMLTDLAGTEKDVKSIYKVGLNTTRLLQASGDVVVGYLLVKSAAVAAAALETASAKDKAFYEGKIAAAKFFAANVLPGVAQARALSEAVDLDVMELDEASF
>NZ_CP014485.1|WP_059214288.1|3726178_3726706_+|GNAT-family-N-acetyltransferase
MPQLIEPSPALHASWLAAEAEWEALGTQDGAGRHLVPDQGLETEEGFRRWTETLREQETNPVGGYVPATHRWIVEDGTFLGAIDLRHRLNGFLFEAGGHIGYSVRPSARGRGVATWALGEMLEEARARGIGQVLITCDEDNEASARVAEHLGAVLEDVRDTVLGRKCRFWITLDV
>NZ_CP014485.1|WP_061404620.1|3725063_3726041_-|zinc-binding-dehydrogenase
MKAVVMHEYGGPEVLRYEEVPDPVPGAGEVRIAVRASGVHFIEGHLRAGGAEGLPPAPGLPAIIGSETAGTVDAVGDGVGAEWLGRRVVTRSPSPGGYASLVTSPVSELHHLPDSLGYEAAVTLIGTGAITLDFLDQVAPAPEDVLLVLSAAGGIGRLAVPHVRRLGTTVVGAAGGPTKTATVRGLGADLAVDYDRPGWSEEIRAHFGTARPVTAVLDGVGGTKAAEAYGLLADGGRLVTIGCASGEWFVPDSEEAAARSVDVVPAIARWAAADVDRRLSRTRALEAGADGSLEAAYQTFALSDAAHAHAEMAARRTTGKVVLLP
>NZ_CP014485.1|WP_015507562.1|3724436_3725051_+|hypothetical-protein
MTSQTYRSAYTAREPGVRALPEDSRRRPPAVPRQAGPPGPACPACGAPGARWHGPLALPLCPSCTGAASPAPAGDPVRLGDLLPVMTATLVRAEHGQPLPERSKAVPSPGEGKPMTCRYCLAPGRWHTTVGGAWIPMEPDPFPAYRVPARHRWRIAPDGTAVPLGRAVPADTCRVSHFSVCPARPAPVESPELMARWRSHGGRG
>NZ_CP014485.1|WP_030310156.1|3722629_3723922_-|M18-family-aminopeptidase
MSRPARFDRGHTDDLLTYLAASPSPYHAVANAAERLEKAGFRQVEETDAWDGTTGGKYVLRGGALIAWFVPEGAEPHTPFRIVGAHTDSPNLRVKPLPDTGAAGWRQVAVELYGGTLLNTWLDRDLGLAGRITLRDGRDVLVNIDRPLLRVPQLAIHLDRGANDGLKLDRQKHMQPIWGLGDDVQEGDLIAFVAEEAGVDAADVAGWDLMPHPVEAPAYLGRDRELVAGPRMDNLLSVHAGAAALAAAATSGELPHIPVLAAFDHEENGSQSDTGADGPLLGSVLERSVHARGGSPEDRARALAGTICLSSDTGHAVHPNYPEKHDPTHHPRANGGPILKVNVNMRYATDGSGRAVFAEACEKAGVPFQNFVSNNAMPCGTTIGPITAARHGIKTVDIGVAILSMHSARELCGADDPFLLANALTAFLEN
>NZ_CP014485.1|WP_003949299.1|3722201_3722432_-|hypothetical-protein
MGLGGCIILIAVGAILTFATDFELEGINVTLVGAILMLVGVIGTIAFTSIARRRRLLMTQTPPVVEGGRTHDDRLI
>NZ_CP014485.1|WP_061404621.1|3734595_3736380_+|aspartate--tRNA-ligase
MHRYRSHTCGELRASDVGSDVRLSGWLHNRRDLGGILFIDLRDHYGITQLVARPGTPAAELLDKLSKETVVRIDGQVVSRGTENVNPELPTGEIEIEVSDVEVLGEAAPLPFTINAEDGVNEERRLEYRFLDLRRERMHRNIMLRTAVISAIRHKMTALGFNEMATPILAATSPEGARDFVVPSRLNPGKFYALPQAPQQFKQLLMISGFDRYFQIAPCFRDEDARADRSPGEFYQLDVEMSFVEQEDVFRPIEKLMTELFTEFGGGREVTSPFPRIPFRESMLKYGNDKPDLRAQLELVDITDVFADSGFKAFAGKHVRALPVPDTAGQSRKFFDGLGDYAVEQGAKGLAWVRVGDDGALSGPIAKFLTEDDVAVLTERLGLKPGHAVFFGAGEFDEVSKIMSAVRVEAAKRSGHFEENVFRFCWIVDFPMYEKDEETGKIEFSHNPFSMPQGGMQDLEEKDPLDILAWQYDIVCNGIELSSGAIRNHEPEVMLKAFEIAGYERETVEREFAGMLRAFRLGAPPHGGIAPGVDRIVMLLADEPNIRETIAFPLNGNAQDLMMGAPTELEESRLRELNIQLRKPVADKAKDKDK
>NZ_CP014485.1|WP_003949288.1|3736470_3736725_-|hypothetical-protein
MVTVLTVTVLAVLVVGAVVLLIRLDSRGPAWLTARRVARGTPGQCVHCGSKRTRVLTTDDALNGSLECRSCHQITRGSGPAPAA
>NZ_CP014485.1|WP_008414096.1|3736788_3737340_-|GNAT-family-N-acetyltransferase
MRVEMPIRTERLVLRPLRAEDADALHAYHRREDVARYLYRPPLDREGCAKLIARSIDSPEWGTTGADLGLAVCLRGQVIGETGLRLRSALAAQAEIGWVFAPEYAGHGYATEAARAVLAAAFGPLKVHRVYARLDADNKPSWRVCERLGMRREAYLVDSDVNPATGTWGSEYVYAMLAREFAG
>NZ_CP014485.1|WP_030307135.1|3737392_3738289_-|glycosyltransferase-family-2-protein
MLLPRIGVVIVTMGTRPRELAALLASVARQDVPATRVVLVGNATPLTDVPDDASGLPLTKLPLIGNLGCPGGRNVGLTLLRDADADACDVVVELDDDGLLIADDVFRTVQQRYARDPALGIIGFRVADEHGHTERRWVPRLRAGDPLRGGPVTAFLGGGHALSLPMLRQIGLWPAEFFFGHEESDLAWRALDAGWSIHYAPDLVLQHPRTSPARHAVYHHHTARNRVWLARRRLPAVLIPAHLALWTLLMTARLRSPSALKAWWGGFFEGLRTPCGPRGPMAWRTVWRMTRLGRPPVV
>NZ_CP014485.1|WP_003949285.1|3738388_3739045_-|HD-domain-containing-protein
MAGYENAEPEVAGVRVPDTRLAAEATELVRETAPELIYHHSRRVYYFGALRGKRRGLSYDPELLYLGAMFHDLGLGEEHRNSGRRFEVDSADEARRFLAARAVPEDSIRRVWTAIALHTTPGIPEFMEPEVALVTAGVEYDVLGLGYDSLDEADRTAIVARHPRPDFKRRILAAFTEGVAPKPETTFGNVKADVLAHFVPGFTPGDFVTTIEESAWPE
>NZ_CP014485.1|WP_030307132.1|3739152_3739620_-|hypothetical-protein
MAPVTLRLMTTALPATTPGPAAPAPGPRPFLLTDIEAAVRASWGADTTTPAHRPHWSPDNPARDQCGVTAMVLNDLLGGELIRGVVRVDGIQTDFHWWNRLGEGIEIDLTHEQFAPEEIVSDGEVVPRPPHFTRLREEYELLRSRVLARLARPAA
>NZ_CP014485.1|WP_003949283.1|3739774_3740170_+|helix-turn-helix-transcriptional-regulator
MQSYTIGQAAQLLGVSPDTARRWADAGRVATHRDDNGRRLIEGQALAALAVEVGQQGADDEEASYTTARNAFPGIVTGVKLGDVAAQVEIQAGPHRLVSLLTREAVEELGLEVGMRATARIKSTNVHIDRT
>NZ_CP014485.1|WP_030307128.1|3740294_3741107_+|molybdate-ABC-transporter-substrate-binding-protein
MASSATTRSPRRAPLAVATAAVLIPLAACGGGDGEKGGDGSASAGSEKKNTQLTVLAAASLTDVFEQAGKAYEKEHPGVRIDFSFAGSQELAAQVKQGAPADALVTADTKTMDGLSGETGDPTVIAKNRLVIAVEEGNPKKVESLKDLTDEQLKVVLAAEEVPVGRYGRQILDAQKLTVKPVSQEVSVRAVLSKVELGEADAGLVYKTDAETVPDKVDAVDIPDGQNAVASYPAATLKGTEHAKEAEAFVKWLSSDKAQELLRKAGFQQP
>NZ_CP014485.1|WP_079076079.1|3741338_3743384_+|molybdate-ABC-transporter-permease-subunit
MGGPVRSGRPGAGAGGAVRRGVPAGLLVPALVGVAFLLLPLVGVLARTDWPSLLHHLTTPQVTQALRLSLVVSGWALLLSLLMGVPLAWLLARVPFPGKALVRSLVLLPMVLPPTVGGVALLLAFGRRGVLGPWLESTFGLTLPFHTAGAVVAAAFVAMPFLVISLEGALAGLRPSLEETAASLGAGPLRVFATVTLPLLAPALAAGAALTWARALGEFGATITFAGNLPGATQTVPLQVYLLLQDSPEAATSVSLLLLVIAMAVLVALRGRWTGGAVREARATPPQGAAAPADPAGFADLGAPEEGPTLEKPPIRPGAGVGAGPAPAPAAEESDLRAELTGYTRFPLTAPAGTTIAVVGPNGAGKTTLLRALLGLTPRAHAEVLLGGRDVTRLPTHRREVAWVPQDGALFPHLSALANTAYGLRARGVPRAEARRQAREWLTRLGVGELAGRRPAQLSGGQAQRVALARALAARPRLLLLDEPLAALDQTTRARVRHTLRRHLAGFGGVCLIVTHDPVEAVSLADRVLVLEGGEAVQDAPPAEVTRHPRSPWVARMLGGNAWEGTAGPEGTVELAGGGLLTTAPGEATPPGPGAPVLAVIAPEAVSLHLARPEGSPRNVWAGTVRELTAVGSRLRVLVTSPEVPALVAEITPAAAADLGLTDGTRVWTAVKATEVTVVGL
>NZ_CP014485.1|WP_003949279.1|3743506_3743791_+|hypothetical-protein
MRSYGTGEAPPRTPTAAPDPDPETAAGEQALLDGGPAHGTRLRVLGRPAVVQVTYPCRTEDGPTPFRVDALYVYRRDPRVHHEPLRYGYDHASP

Crispr_ID: NZ_CP014485_21

• CRISPR_ID: NZ_CP014485_21
• CRISPR_location: 3803741-3803836
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_21

Consensus_repeat	Method
CCAGGGCGCCAACCTCTGCCTCCT	CRISPRCasFinder

spacers of NZ_CP014485_21

>21.1|3803765|48|NZ_CP014485|CRISPRCasFinder
CGCCCACTGCACGACCGGCACGAACGACCCGGCCCGGGTCACCAACAC

CRISPR arrays and Neighbor proteins around NZ_CP014485_21

CRISPR arrays

The CRISPR arrays of NZ_CP014485_21

>merge|NZ_CP014485|21|3803741-3803836|CRISPRCasFinder
CCAGGGCGCCAACCTCTGCCTCCTCGCCCACTGCACGACCGGCACGAACGACCCGGCCCGGGTCACCAACACCCAGGGCGCCAACCTCTGCCTCCT

>NZ_CP014485|21|16|3803741-3803836|CRISPRCasFinder
CCAGGGCGCCAACCTCTGCCTCCT	CGCCCACTGCACGACCGGCACGAACGACCCGGCCCGGGTCACCAACAC
CCAGGGCGCCAACCTCTGCCTCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_031178827.1|3806890_3807580_-|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|274926
NZ_CP014485.1|WP_061404638.1|3792996_3803286_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NZ_CP014485.1|WP_008408879.1|3810165_3810963_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224045
NZ_CP014485.1|WP_003949238.1|3788986_3789340_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|163261
NZ_CP014485.1|WP_079076011.1|3807826_3808981_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl|CDD|182464
NZ_CP014485.1|WP_015507582.1|3804650_3805004_+|PRC-barrel-domain-containing-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_030307076.1|3790206_3790905_+|sensor-domain-containing-protein	unknown	unknown	gnl|CDD|379374
NZ_CP014485.1|WP_061404637.1|3790911_3791712_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NZ_CP014485.1|WP_030771211.1|3792718_3792928_-|MbtH-family-protein	unknown	unknown	gnl|CDD|377081
NZ_CP014485.1|WP_008408883.1|3814680_3815715_+|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238566
NZ_CP014485.1|WP_033239344.1|3803951_3804350_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003949226.1|3805140_3805506_+|PH-domain-containing-protein	unknown	unknown	gnl|CDD|377953
NZ_CP014485.1|WP_061404640.1|3808977_3810096_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl|CDD|227119
NZ_CP014485.1|WP_061404641.1|3811075_3814402_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173800
NZ_CP014485.1|WP_061404639.1|3805483_3806710_-|hypothetical-protein	unknown	unknown	gnl|CDD|226614
NZ_CP014485.1|WP_061404635.1|3786083_3786752_-|DUF998-domain-containing-protein	unknown	unknown	gnl|CDD|377627
NZ_CP014485.1|WP_030307077.1|3789336_3790035_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404636.1|3788394_3788856_-|DUF2269-family-protein	unknown	unknown	gnl|CDD|370783
NZ_CP014485.1|WP_033239850.1|3787135_3788380_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP014485.1|WP_008410719.1|3791699_3792722_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|130256

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_031178827.1|3806890_3807580_-|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|274926	TIGR04025, hypothetical_protein, PPOX class probable FMN-dependent enzyme, DR_2398 family. Members of the PPOX family (see pfam01243) may contain either FMN or F420 as cofactor. This subfamily consists of proteins mostly from species that lack the capability to synthesize F420, and therefore most likely all bind FMN.	7.71105e-79
NZ_CP014485.1|WP_061404638.1|3792996_3803286_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP014485.1|WP_008408879.1|3810165_3810963_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	8.33355e-135
NZ_CP014485.1|WP_003949238.1|3788986_3789340_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	8.53379e-30
NZ_CP014485.1|WP_079076011.1|3807826_3808981_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl|CDD|182464	PRK10441, PRK10441, Fe(3+)-siderophore ABC transporter permease.	1.93755e-89
NZ_CP014485.1|WP_061404640.1|3808977_3810096_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl|CDD|227119	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism].	1.32148e-76
NZ_CP014485.1|WP_030307076.1|3790206_3790905_+|sensor-domain-containing-protein	gnl|CDD|379374	pfam13796, Sensor, Putative sensor. This family is often found at the N-terminus of proteins containing pfam07730 and pfam02518. The N-termini of proteins containing these two domains often function in stimulus sensing.	1.25239e-26
NZ_CP014485.1|WP_061404637.1|3790911_3791712_-|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	4.13339e-20
NZ_CP014485.1|WP_030771211.1|3792718_3792928_-|MbtH-family-protein	gnl|CDD|377081	pfam03621, MbtH, MbtH-like protein. This domain is found in the MbtH protein as well as at the N-terminus of the antibiotic synthesis protein NIKP1. MbtH and its homologs were first noted in gene clusters involved in non-ribosomal peptides and other secondary metabolites by Quadri et al. This domain is about 70 amino acids long and contains 3 fully conserved tryptophan residues. The structure of the PA2412 protein shows it adopts a beta-beta-beta-alpha-alpha topology with the short C-terminal helix forming the tip of an overall arrowhead shape. MbtH proteins have been shown to be required for the synthesis of antibiotics, siderophores and glycopeptidolipids.	2.14237e-27
NZ_CP014485.1|WP_008408883.1|3814680_3815715_+|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl|CDD|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	5.07307e-63
NZ_CP014485.1|WP_061404639.1|3805483_3806710_-|hypothetical-protein	gnl|CDD|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	8.36548e-12
NZ_CP014485.1|WP_061404636.1|3788394_3788856_-|DUF2269-family-protein	gnl|CDD|370783	pfam10027, DUF2269, Predicted integral membrane protein (DUF2269). Members of this family of bacterial hypothetical integral membrane proteins have no known function.	0.000691355
NZ_CP014485.1|WP_061404641.1|3811075_3814402_-|S8-family-serine-peptidase	gnl|CDD|173800	cd07474, Peptidases_S8_subtilisin_Vpr-like, Peptidase S8 family domain in Vpr-like proteins. The maturation of the peptide antibiotic (lantibiotic) subtilin in Bacillus subtilis ATCC 6633 includes posttranslational modifications of the propeptide and proteolytic cleavage of the leader peptide. Vpr was identified as one of the proteases, along with WprA, that are capable of processing subtilin. Asp, Ser, His triadPeptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	3.78759e-80
NZ_CP014485.1|WP_061404635.1|3786083_3786752_-|DUF998-domain-containing-protein	gnl|CDD|377627	pfam06197, DUF998, Protein of unknown function (DUF998). Family of conserved archaeal proteins.	4.06517e-08
NZ_CP014485.1|WP_003949226.1|3805140_3805506_+|PH-domain-containing-protein	gnl|CDD|377953	pfam08000, bPH_1, Bacterial PH domain. This family contains many bacterial hypothetical proteins. The structures of Structure 3hsa and Structure 3dcx show similarities to the PH or pleckstrin homology domain. First evidence of PH-like domains in bacteria suggests role in cell envelope stress response.	4.12332e-63
NZ_CP014485.1|WP_033239850.1|3787135_3788380_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.85872e-87
NZ_CP014485.1|WP_008410719.1|3791699_3792722_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	4.8717e-114

Protein sequences

>NZ_CP014485.1|WP_061404638.1|3792996_3803286_-|non-ribosomal-peptide-synthetase
MPSVPSDRPSAAFPLTAAQRGLWFAQRLDPDSPAYNVAEYVEVRGELDVRALRRAVRHVEEETEALRLTFGERDGVPWQRVRAQAGIEVPVSDVSGYADPHAEAVRRMTAELARPADLARGPLVRMALYRLAEGHHLFHQQVHHLAVDGYGAVLALARIAEVYTLLVTAPGEPVPVRPAPLGPVLADEEAYGNSEQRSRDGEFWAAYLDGAPAPAGLVPGAPGGPARRVRAVSRHLGAEEAAGLRAAAKRAGVAWPAFLMAALGVCLHRERGLGEVVLGLPVTGRRTPAARTTPAMLSQVLPMRLAVSPADRVADVARRASAEARQVLRHQRYPAQELRRERGLGVREAQAGPAVNVLAFDDTLSFGPSPATLHNLSVGPVEDLAVAAHASYGDGGLSLDLLGDADRYDEAGLARHHEAFCRMLAAFAEDPERPLGALPLVPAPEHARLVRLGTGPVAEGGPLPTLPEQFAAQAARTPWATAVVCGDERLTFAELDARVRALSVELAARGARPGERVAVGLERSADLVTALLAVLRSGAAYLPVDPSYPVDRLAYMLQDAAPVALVARPGTAVPHEGLELVDPAAVVPGGDGGVPEPPVPEPHDAAYVIYTSGSTGRPKGVVVEHRSLAQLLEHHRREAHALAAESLGRRLRVALTAAISFDASWDPVLWMLAGHELHLADDATRRDPEALAAFLAARRIDAVETTPSHLRQLLAAGLLAGDGHHPRVLALGGEPVDDALWAELRDHDELIVLNYYGPTETTVDAVTARVTGTAPAIGRPVAGARAYVLDSALHPMPLGTPGELYLSGEGVARGYAGRPGLTARRFLPDPYGPPGARMYRTGDLARWRPEGTLEFLGRTDDQVKIRGHRVETGEVEAALRALPGIADAAVAPAGPAGGERRLAAYLVPGPGGTDPAEVRDLLTAALPDHLVPALYAVLDRLPLTPNGKLDTARLPEATAPRSAGGAPRTEDEERMCAEFAACLGLDAVGRDDDFFRLGGHSLLATRLIGRVREAFGAEVAIRALFDHPTPARLLTALDRTAPALPPLRAARPRPARVPLSPAQRRLWLLERLGGAGTAYHLPVGLRLSGPLDRDALAAALGDVAERHESLRTVVAEDADGPYQRVREPAPVPLAVAPLPRTGSPAPDPEPFDLAGEPPLRARLFTDGDRDHLLVLTFHHIAADGWSMLPLLGDLGDAYAARRAGRAPGLTPLPVQYADYALWQRELLGTPDAPTGRAARQLAHWRAALDGAPAESAPPADRPRPDRPSGRGGAVPVTVPAAVHRALLERAAASGTSPFMVLHAALAALLSRLGAGDDLVVGTPVAGRPDEALAGLVGFFVNTLALRTDTSGDPDLTTLLARVREADLAALAHQELPFEQVVSAVSPPRHPARHPLFQVMLALDNTPAPRAALDGLTVRRDTATGRTGAKFDLTWDLAERHTADGAPAGIGGELEYSEDLFDQATAERYAAQFTTLLTALLDRPDTPFTDLPFLGTRDRAAALDENGPTRPPATPDWTLTDVLATRAAADPGRTAVVDATGRLTFGELQDRAERLARRLAAAGVRPGDRVALALPRSAAALAALLGVLRAGAVHVPLDTTHPPARNALVLRTAAPRLVLTTATTDEAVPATGHPRLVLAEDPDDWPATGPLPAPPRPEDAAYVLYTSGSTGRPKGVVVDHRALAHLYAHHREHLIGPAQAAAGGRQLRVALTAALTFDASWDPVLWMAAGHELHLVDDATRRDPEALTAHLRERAVDVVETTPSFAELLRSCGLFAPGHHRPRVLALGGEAVTEPLWEELAALPDVTAWNLYGPTEATVDALVAPVTAGTRPHLGRALPGARARVLDARLAPAAPGATGELYLTGPGLALGYERAPAATAARFLPDPYGPPGSRMYRTGDLVRRRAGRLEYLGRADGQAKVRGFRVETGEVEAALLRHPGVALAAATVRPGPDGSGRLLAWAVPAEGHRPTGRELRAHVATRLPSYMVPAAVVPVATLPLTVHGKTDFAALPDAPGPEAPADGTAVPRSAREEILCALFAECLGQPRVTRDDDFFALGGHSLLALGLIGRVRSAFGVELSVRTLFDATTPAALAARLDAAQPARPALRRAERPARPPLSPAQRRLWFLHGLDPADASYHIPVAVRLDGRLDRAALRDALADVTARHESLRTRVQDHEGEPCQAVLDPADARPALPTTPVTEAEVEAALREAAALPFDLAADLPLRAELFALGAERHVLLVTVHHIAADGWSMGPLAEDLAGAYAARTAGRVPQWAPLPVQYTDYTLWQADLLGDPDDAESVAGRQLAYWAEQLRGAPDEVPLPADRPRPARATGRGGTVDLTLPPATTEAVTRLARATGTSPFMVLHAALAALLTRTGAGEDLTVGTPVAGRTDEALHPLVGFFVNTLPLRVSTGGDPTFRALLARVKETDLAAYAHQDLPFERLVEEVRPARSLNRHPLFQTMLTLNNTRPPRLDLPHLAATLDGVASGGAKFDLSFSLREEDGTLTGTLEYSADRFEPGTARRIAAWFAHLTAAATAAPDTPVRQLPLHGAEEEARLLALGRGEPGEPVTGTVLDRFAATVAGARHGEPAVTAPDGTLTFAELDARARHVAALTASAGVVPGDRVAVLLPRSTDSVAALLGVLTAGAVHVPLDPALPEARLAAVLADARPRLTLATTATAPLLPAGQPRLLLDQAPPAAPAPTTPRPTPDDPAYLLHTSGSTGTPKGVLVGHRSLARLLDHHRRHLFAPAVRATGRARLAVALTAALTFDAAWDPLLWLLDGHHLHLVDDQVRRDPEALVDAVRTHRLDVLETTPSHTAHLLDAGLLADGAHHPAVLALGGEAVPAPLWTRLRAAPATRCLNLYGPTEATVDTLTADLADTPHPVLGTPVTGTRAHVLDAALRPTPPGVPGDLHLAGDSLALGYPGRPAETAARFVPDPYGPPGSRMYRTGDRAVRNADGSLVFAGRADGQVKIRGFRVETGEVAAVLEAHPQIAHAAVVPHEDPEAGTTLTAHLVPAPGTDPNPEEIRAHATRHLPAYMVPTGWSTLDRLPLTAHGKLDTAALPVPRALAVPTGGRVPRTPREDVLCTLFAEALGAERVTIDDDFFALGGHSLLATRLIGRIRATLGTDLSIRTLFEAPTVAALAGRLDSAADDDSLATLLPLRTTGSLPPLFCVHPAGGLAWPYAGLLPHLDPGQPLYGLQTPNLDGTAPFPDSIEEMAATYAAEIRAVQPHGPYRLLGWSFGGNVVQEIAVQLQEAGEEVALLAILDAFPLAPQDDLDSAPRDAVFRALLANLGVGEEAAVGSGGVDAAAVREEFRRAGSPLGALEPATIDAMVDNFAGQARLMRRYTPRTFHGPVLFFTATEGRPADAFPHALWDPYLTGPLHDIPVACAHAQLMSPDARATVGPVLAEALAALAGPEATPPAP
>NZ_CP014485.1|WP_030771211.1|3792718_3792928_-|MbtH-family-protein
MTNPFDDPRTHHRVLVNDEGQHALWPSFATVPAGWEAVFGPADQDACHAYVEEHWTDLTPRSARRTVAA
>NZ_CP014485.1|WP_008410719.1|3791699_3792722_-|ATP-binding-cassette-domain-containing-protein
MSRARPAPPGDGPALRAEGLTKRFGTKQALAGVDLDAPAGTVLGLLGPNGAGKTTTVRVLTTLLRPDTGRAWVAGHDVRTAPEAVRARLGLSGQYAAVDEKLTGRENLYLVARLYGTGRGPARRRATELLDRFRLSEAADRPSGTYSGGMRRRLDLAGALVARPAVVVLDEPTTGLDPRGRADTWECVRELVATGTTVLLTTQYLEEADQLADSVAVIDHGRVIAQGTAAALKSRVGGERLTLTLPDPASRPGALDLLAPLTPHRPHLDPRTGVLTLPTDHGPATLEQALAALRHAGVPLGEVSLAPPTLDDVFLALTGQETSTAPAPGPVPTKEPAWQP
>NZ_CP014485.1|WP_061404637.1|3790911_3791712_-|ABC-transporter-permease
MAAVTRLARDATLIAWRNLLNLRRTPGSVVAALIQPVMFVLLLSYVFGGSLGGDAYRTYLMGGIFAQAVTFNAAFTALGLANDLDRGIVDRFRSLPMPPMAVILGRTLSDLTMSALTVAVTSLCGLFIGWRIAGTLPEAVLAYLLILLFAFAMSWVGATIGLTARSVEVAQSAGLIWLFPVTFLSSAFVPTATLPTALQPVADWNPVSATATALRTLFANPAPPTAPLRDTWPVTHALPYALLSTLAITAVFMGVAVRRFRAMGRG
>NZ_CP014485.1|WP_030307076.1|3790206_3790905_+|sensor-domain-containing-protein
MATADIPTADIPTACPLPHVSEQPAGAVRRGPLSAAAWREYGYVFTSFPLAIAGFVLAVTLFSLGAGLAVTVVGFPVLVALLAGARGLGAGERGRASGLLGLRTKEPAPVPAGGIKGRLADVAGWKAVLFQFVMFPWRIASFVVTLTLLLTGWVVALLPLYAWVFPTFVGWPGYQLFDWTDGAGVRHAYYLESFWQIGAASLVGIGLVLLTPVVVRALNRVDRAAVRGLLAG
>NZ_CP014485.1|WP_030307077.1|3789336_3790035_+|hypothetical-protein
MSADMAPPPPLDDPVERYAVELAAALRGPAGARERLVVEVRDGLAETVAAYEAAGVPAERAVREAVAEFGSVAEVAASCQRELTVAQARHTARALALTGPFLVACWWLVRGTGDGQGGVSGFAQQVAVQLSSAAAVAVVLAALALAATGAWGRWLPVATERLPAAVAWTGTAASVAMAVTTLTLATAAFLAEQWPLTVLAGALAAASHAVVAGSARVCRECARLSSREPAVA
>NZ_CP014485.1|WP_003949238.1|3788986_3789340_+|helix-turn-helix-transcriptional-regulator
MRHDAVRGHLDGLLLAVVEPGPLHGYAIITAVQERSGGALELRTGTIYPALNRLERVGLLRSDWEAVGQRKRRRYELTEAGRRQLAEERSAWRDFTRVIGAVLDPAPVPGAATGAAT
>NZ_CP014485.1|WP_061404636.1|3788394_3788856_-|DUF2269-family-protein
MAKLFLSLHVLAAILAIGPITVAASMFPRLARTAPTPETPALLHKICRSYAYVGAAVPVLGIATGAALGVLSDAWLVVSIVLTGVAAGVLVAVILPGQSELLEPLEGGEGAAAGEEERRAAGARLAMTTGVFNLLWAAVVVLMIVRPGSTTGA
>NZ_CP014485.1|WP_033239850.1|3787135_3788380_+|MFS-transporter
MPLALLALSVVAFGIGTTEFVSMGLLPQIADGVGVSVPQAGNLISAYALGVVVGAPLLTGLGAKIPHKKLLLLLAGLFVVGNVASALAPGFGTLFAARVLAGLPHGALFGVGAVVASRLVAPERAARAVSTMFLGLTVANIVGVPAGTALGQQFGWRSAYLAVAVIGLIALAALARLVPHQPRAEGAGIRHELKAMGNRHIAIGLATAVVGFGGCFAVYSYLVPMLTEVTGMASSSTTLVLALYGVGMTLGTLLAGPMTDRALRPTLYGGLAVMAVVLFAFYFAVQHTVTALVCVLLIGAMGSFITTPVQMLLMAKAEQAPTMAAASNHSAFNLANAGGAWLGGLVISAGWGWASPALVGASLAAVGLGLAVVGGVMDGGFGRGKRSTVVAGAGAKAGVKDEAEVQAAGVERAG
>NZ_CP014485.1|WP_061404635.1|3786083_3786752_-|DUF998-domain-containing-protein
MTGTFTTPGPLHSAAATQRSTARWLTTGGVVAGPLFLAAGLAQGLTREGFDFTRNAISQLALGGAGWVQTLSFVCTGALLVAGAAGLRRTLRRGSAGRWAPALVGVFGLSFWAAAAFPADAGAGFPAGSPDATVMSGHGAAHMAAGMIGYLALCAAFVVLARPLAARGLRGWAVAARVVPVAVLAGFMASAASVLAFTAGAGLGLLWLSAVMARLADAPGDR
>NZ_CP014485.1|WP_033239344.1|3803951_3804350_-|hypothetical-protein
MTKHHAARILIGAGAAFGLVLGATGAANAAPSNPIKTQGGYAQWNADPSGSIPGDSIRACDNTADGWGIEAWLDINRDGTIDRIASTRGHNAPYCTSWKSGNIPEGTPVTVYAVTVNGGIVLEKGGALWSKA
>NZ_CP014485.1|WP_015507582.1|3804650_3805004_+|PRC-barrel-domain-containing-protein
MSDGIWGYQPTAGHTAGTDLIGYKVEATDGTIGKVDKHSDEVGSAYLVVDTGVWIFGKHVMLPAGTVRTVDGAERKIHVELTKEQIKNSPEFDKDRHAGDAQYHDQLGGYYGGHRPL
>NZ_CP014485.1|WP_003949226.1|3805140_3805506_+|PH-domain-containing-protein
MALFGNAHTVDPGSAQQEYARLLGQGEQVHAAYLLIRDTILFTDRRLILVDKQGITGKKVEYHSIPYRSITHFAVETAGTFDLDAELKIWLSGATTPVQKTFTKGVDIYEVQAILTQFVTR
>NZ_CP014485.1|WP_061404639.1|3805483_3806710_-|hypothetical-protein
MSDTATQEKWERVADWGRRLRRPESSARRSLLLILKSALAATVSWFVSYELMNATSPAFAPFSAVLMVQVTVYQSVVQSLRYVGAVTAGVAVQAVLGLSAGPDLVTFALVALVALVISRWRLLGAQGSQVATAAFFAFATYTGASSDTDQVKELGQIVLLVLIGSAVGVGVNVLIAPPLRYRSAEWGIRALAQEIHDLLDTMAPELGEGAPDADTTQGWRDRADRTGTLISQSREGLRTARESLRLNPHPWARRRRGTLTFEAYDRTMEALVRMISQVTAITRSLDLQHQDEKQQEEESGPDRDYAPFLRAYATFLSSVVDFTEILATLDEDHLRDQAGRLDEAADGLERCRREVVRTTEDRGLSLTDPTEPYGVLVVEATRLSEECRYTAGVLGNSAENGSSGSRTA
>NZ_CP014485.1|WP_031178827.1|3806890_3807580_-|pyridoxamine-5'-phosphate-oxidase-family-protein
MTNPAPEAPATGLHHSLARLTRVPDARGLGLTEPAVPAAPLVPEAPAASPLPAGYTELTGVEELDALLGVPHPIVIDKVHDRLDAQDLDLLSRSSFCSLSTADAEGNCDVSPRGGVPGFTHVVDPGTLALPDRPGNRRGDSFRNILTNPHVGLLYLVPGVMDVLRINGRARILTDAPFFDALVEKNQRPKLALVVEIDEIYRHCPASLRRSGIWSPDTWENAAGGTSPA
>NZ_CP014485.1|WP_079076011.1|3807826_3808981_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MNGPADREGRPADPSGPPPSRTRSTALLDLDKRPDAEGATAIAAPPPRRSVRSRPALAAGLVLALVGLGLTLVASLAVGSGDVPFADVLGTFLDPDAENKAQLIVGEVRIPRTVAGLLSGVALGLAGTVMQGVTRNPIADPSLLGINAGASLSVVFAISVLGLGASQQYLWFGFLGALIAALVVYGVGSLGREGATPVKLALAGAATTAVLTSLTTTMLLTDRQSYDQFRFWQIGALNTRSVEVLSEAAPFIVVGGLLALTLGSQLNALALGDDLARGFGQRVGLVRGVSAVAVVLLCGASTVVAGPIGFVGLAVPHIARLVTGPDYRWVLPYSMVLAPMLLLWADIVGRVVAQPGEVQVGVVTAALGCVPFIWLVRRRKLVEL
>NZ_CP014485.1|WP_061404640.1|3808977_3810096_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MSDRATSSFEKAAPARTDASPLHVSEAVLAEAARTVAGARRRGGRRSVLVGLVLALAAFAVFAVSLSVGDMVIPLADVLATLFGGGDAGSQFVVLELRLPRALLAVLVGAGFGMAGAVFQTVLRNPLASPDVIGISSGASAAAVTASMVFAVSGLALSASALIGALIAGTLIYLLAWRKGVVGARLVLVGLGVGFGLNSLVWYLMSRAEVSNAQNALLWLTGSLNGRSWNQVWPQLIALAVLVPLTFAAARALPALQLGDDTASGLGARAERNRLALLACGVALAGASTAAAGPVAFVAFVAAPVARMLLPGRGAVLPHAALAGALLVLLADFAAQHALPGTQLPVGVVTSVVGAPYLLWLLARANRVGRGG
>NZ_CP014485.1|WP_008408879.1|3810165_3810963_+|ABC-transporter-ATP-binding-protein
MSAEHTLEARDVRIGYDGREIVPGLSVKIPPGRFTVIVGPNACGKSTLLRAMARLLAPTSGAVLLDGRPVQQTPTREVASVLGILPQSPVAPEGITVSDLVARGRYPHQGWFRRWTAEDDAAVGAALLSTDVLDLAERPVDELSGGQRQRVWIAMALAQRTDILLLDEPTTFLDVAHQMDVLDLLTDLNRERGVTLVAVLHELNMACRYADHLIAMKQGEVVAEGAPSDIVTEQLVSDVFGMRCSVVPDPASGTPLVVPLGRHHV
>NZ_CP014485.1|WP_061404641.1|3811075_3814402_-|S8-family-serine-peptidase
MVAAAVAVALAAGTAPSAVAQPDPRGTSGDRAHAPDRVKRHLTLVTGDRVGLDADGTPVTFRPAKGRERIPVKRMSDRGHTLVVPADAHRLVVSGKLDRRLFDITELSRPENLRAQRDGLKLIVGYRGKQAHAAKAQVREAGGTEVGRSLTSLNAESVTTPAGDVPEIWKALTAGPGDGERVTTAAGIDRVWLDGVRRASLDKSVPQIGAPTAWKAGFTGKGVKIAVLDTGTDATHPDLKGQVLAEKNFSSAEDTVDRVGHGTHVASIAAGTGAASGGAFKGVAPDAKLLAGKVLDDDGFGEDSGILAGMEWAVAQGADIVNLSLGGTDTPEVDPLEAAVDKLSAEKGVLFAIAAGNEGDGAGTVGSPGSADAALTVGAVDDKDELADFSSRGPRVEDGAVKPDVTAPGVDTTAAIPSDSLIAQEVGENPAGYATISGTSMATPHVAGAAALLKQQHPKWSYAELKGALTASAQPGPYNPFQQGSGRIAVDRALKQTVVADPVSVSFGVQQWPHTDDEPVTEQVRYRNTGTADVTLDLKVTGTGPKGKPAPAGFFTLGADRVTVPAGGTAEVALTADTRLGGDADGTYAAYLVATGGGQTVRTAAAVEREVESYDLTVKHLGRDGRPAAEAETTVFRFDAGADFPFLDPQVVDGTAKIRVPKGTYVVDSNVYQDPEDVTKGVDWIAQPKVAVTKDTTLTFDARKAKPVKITVPDSKAESQIFSPDYGVETEDDAVTFGWVADSPAGMRTLHVGPKITDGSLTQHWSGTWTRGATTQFDIAVGGKVERLATGYSRKFTTGQLAKVKLAMGAAAPKKTGEVTAWPLLPSQNSGWVVSGEQKLPGTRTLYLSTADQVRWDMDFSQLGDLDEEGFPAYETGYQVAAGAGFRPGWTYRKSVNTAVFGPLVNKEFGVFRDGNEIGGYLPLLADGRGNPGGIELSKATSVLYRNGKETGRNSDPLAGEEVFRVPAAAADYRLKATVRHSAKISPLSTRVDVDWTFRSKKTGDHTPLPVSTVRFSPEVAADGTAKAGKTVTVPVKVQGAAAGKNLKSLTTYVSHDGGKNWKKVPVKKGKITVKNPAKGKAVSFAAKVTDKKGNTSKVRIYSAYLGK
>NZ_CP014485.1|WP_008408883.1|3814680_3815715_+|iron-siderophore-ABC-transporter-substrate-binding-protein
MNDSAFSGKAARSSRRRKTATLAGAVAALLVGLTACGAGGDEQAEKPAEGKASSGAFPAKVATKFGEITIDEAPKRIVALGWGDAETALALGAQPVGASDWLPFGGEGVGPWAKGMYDKKPELIGTMEPEFEKIAALKPDLILDTKSSGDQTRYDTLSKIAPTVGVPKGGDMYMTSWEKQTEMVAGALGKKDEGAELIADTEKKFAAAAKEHPEFKDKTITVGSRTSEGFGAYVGGTGRVDFVKRLGFVNNPEIEKLAGDSFSVSVSKEKLDLLDADLTVMAPIGISAKEISDDPLYKAVPSVKDGRSIVFDDKDISQAFATDSVLSVGYALDKVVPLFSEKLK

Crispr_ID: NZ_CP014485_22

• CRISPR_ID: NZ_CP014485_22
• CRISPR_location: 3945009-3945098
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_22

Consensus_repeat	Method
CCGTGCCGGTCACCGACTGGCCTCAA	CRISPRCasFinder

spacers of NZ_CP014485_22

>22.1|3945035|38|NZ_CP014485|CRISPRCasFinder
TCGCCGGCCGGGCTGTTGGTTGCTGGGCTCCGTCTCGA

CRISPR arrays and Neighbor proteins around NZ_CP014485_22

CRISPR arrays

The CRISPR arrays of NZ_CP014485_22

>merge|NZ_CP014485|22|3945009-3945098|CRISPRCasFinder
CCGTGCCGGTCACCGACTGGCCTCAATCGCCGGCCGGGCTGTTGGTTGCTGGGCTCCGTCTCGACCGTGCCGGTCACCGATTGGCCTCAA

>NZ_CP014485|22|17|3945009-3945098|CRISPRCasFinder
CCGTGCCGGTCACCGACTGGCCTCAA	TCGCCGGCCGGGCTGTTGGTTGCTGGGCTCCGTCTCGA
CCGTGCCGGTCACCGATTGGCCTCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_008405085.1|3950469_3950841_-|hypothetical-protein	unknown	unknown	gnl|CDD|226318
NZ_CP014485.1|WP_003949070.1|3952135_3952348_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_031178789.1|3937616_3938090_+|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|379275
NZ_CP014485.1|WP_008405080.1|3951764_3952139_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_010644926.1|3941547_3942546_-|CHAD-domain-containing-protein	unknown	unknown	gnl|CDD|214880
NZ_CP014485.1|WP_010644928.1|3942529_3944740_-|RNA-degradosome-polyphosphate-kinase	unknown	unknown	gnl|CDD|235469
NZ_CP014485.1|WP_015507620.1|3945674_3946709_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003949082.1|3941224_3941452_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin	unknown	unknown	gnl|CDD|227737
NZ_CP014485.1|WP_061404659.1|3938185_3939028_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP014485.1|WP_030306898.1|3947663_3948671_-|ABC-transporter	unknown	unknown	unknown
NZ_CP014485.1|WP_008411241.1|3939118_3939487_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404661.1|3949160_3950435_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|227277
NZ_CP014485.1|WP_008411247.1|3940820_3941228_-|PIN-domain-nuclease	unknown	unknown	gnl|CDD|350322
NZ_CP014485.1|WP_003949076.1|3948667_3949057_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224639
NZ_CP014485.1|WP_003949073.1|3951068_3951512_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003949068.1|3952634_3953468_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	unknown
NZ_CP014485.1|WP_003949078.1|3946705_3947629_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP014485.1|WP_010644913.1|3936958_3937507_+|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224759
NZ_CP014485.1|WP_018470082.1|3940307_3940766_-|DUF1992-domain-containing-protein	unknown	unknown	gnl|CDD|378159
NZ_CP014485.1|WP_061404660.1|3939587_3940286_+|type-1-glutamine-amidotransferase-domain-containing-protein	unknown	unknown	gnl|CDD|153235

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008405085.1|3950469_3950841_-|hypothetical-protein	gnl|CDD|226318	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown].	1.37204e-17
NZ_CP014485.1|WP_031178789.1|3937616_3938090_+|nuclear-transport-factor-2-family-protein	gnl|CDD|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.20147e-18
NZ_CP014485.1|WP_010644928.1|3942529_3944740_-|RNA-degradosome-polyphosphate-kinase	gnl|CDD|235469	PRK05443, PRK05443, polyphosphate kinase; Provisional.	0
NZ_CP014485.1|WP_010644926.1|3941547_3942546_-|CHAD-domain-containing-protein	gnl|CDD|214880	smart00880, CHAD, The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family. It has conserved histidines that may chelate metals.	3.1802e-06
NZ_CP014485.1|WP_003949082.1|3941224_3941452_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin	gnl|CDD|227737	COG5450, COG5450, Transcription regulator of the Arc/MetJ class [Transcription].	4.83634e-05
NZ_CP014485.1|WP_061404659.1|3938185_3939028_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.65549e-20
NZ_CP014485.1|WP_061404661.1|3949160_3950435_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|227277	COG4941, COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription].	6.0493e-100
NZ_CP014485.1|WP_008411247.1|3940820_3941228_-|PIN-domain-nuclease	gnl|CDD|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.32034e-60
NZ_CP014485.1|WP_061404660.1|3939587_3940286_+|type-1-glutamine-amidotransferase-domain-containing-protein	gnl|CDD|153235	cd03141, GATase1_Hsp31_like, Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein. Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein (EcHsp31). This group includes EcHsp31 and Saccharomyces cerevisiae Ydr533c protein. EcHsp31 has chaperone activity. Ydr533c is upregulated in response to various stress conditions along with the heat shock family. EcHsp31 coordinates a metal ion using a 2-His-1-carboxylate motif present in various ions that use iron as a cofactor such as Carboxypeptidase A. The catalytic triad typical of GATase1 domains is not conserved in this GATase1-like domain. However, in common with a typical GATase1 domain, a reactive Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For EcHsp31, this Cys together with a different His and, an Asp (rather than a Glu) residue form a different catalytic triad from the typical GATase1 domain. For Ydr533c a catalytic triad forms from the conserved Cys together with a different His and Glu from that of the typical GATase1domain. Ydr533c protein and EcHsp31 are homodimers.	8.20186e-98
NZ_CP014485.1|WP_003949078.1|3946705_3947629_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.57315e-66
NZ_CP014485.1|WP_010644913.1|3936958_3937507_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.71256e-18
NZ_CP014485.1|WP_018470082.1|3940307_3940766_-|DUF1992-domain-containing-protein	gnl|CDD|378159	pfam09350, DUF1992, Domain of unknown function (DUF1992). This family of proteins are functionally uncharacterized.	3.47702e-13
NZ_CP014485.1|WP_003949076.1|3948667_3949057_-|GntR-family-transcriptional-regulator	gnl|CDD|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	2.16897e-29

Protein sequences

>NZ_CP014485.1|WP_010644928.1|3942529_3944740_-|RNA-degradosome-polyphosphate-kinase
MLRTPGETPDPLEQGPQPPLASLTSAHRAQPAADLDSDPDDYPGDDEAELPEGRFLDRERSWLAFNERVLELAEDPYTPLLERANFLAIFASNLDEFFMVRVAGLKRRIATGVATKSASGLQPREVLEMIWARSRELMARHAACYQQDIAPALADEGIHLVRWAELTEEEQARLFTLFRQQIFPVLTPLAVDPAHPFPYISGLSLNLAVVVRNPVSGHRHFARVKVPPLLSRFLEASPERYVPIEDVIAAHLEELFPGMEVLAHHMFRLTRNEDLEVEEDDTENLLQALEKELMRRRFGPPVRLEVEESIDPYVLDLLVRELKISDAEVYPLPGPLDLTGLFGIAGLDRPELKYKKFVARTHRDLAEVESASAPDIFAAVRERDVLLHHPYDSFSTSVQAFLEQAAADPDVLAIKQTLYRTSGDSPIVDALIDAAESGKQVLVLVEIKARFDEQANIKWARKLEESGCHVVYGLVGLKTHCKLSLVVRQEGELLRRYSHVGTGNYHPKTARLYEDLGLLTVDPKVGADLSDLFNRLSGYSRRESYRRLLVAPHSLRAGLVARIHQEIEHHRAGREAYVRIKVNSMVDEAVIDALYRASMAGVPVDVWVRGICALRPGVPGLSENIRVRSVLGRFLEHSRVFVFGNGDEPEVWFGSADMMHRNLDRRIEALVRVTDPAHRATLDRLLETGVADTTSSWHLDADGEWTRHSHDAEGKPLRHVQEMLIDARRRRRAPTP
>NZ_CP014485.1|WP_010644926.1|3941547_3942546_-|CHAD-domain-containing-protein
MPRLPEPDHLPEQAAGPAPAAAPVATALRAEAAAFLRALRHHTEAAQDPQEAREAARSLGRSARRLGATLHTFRPLLDREWADRLRPELTWLSGVLADEHLVAARLTRLLASLHRLSGPAAPRRGGPGIGAAKAGALLERRLTLARTRAHSACLTAFASARLHALVDEVALLGGDVPLAEDAHLRPAGRADTLAEAAARRLSDAVTALPLHRAGHPYNADALALAVPAPDGQDTPWHQVRLLLRLHRYAQEVVAPDAAPDPRVTAARHALDHHRDASEAAHEAASAAATPRIAPTTAYALGVLHADQRHEVEAARYAFQRAWAGEAVGVGGE
>NZ_CP014485.1|WP_003949082.1|3941224_3941452_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin
MSRTVIDLDDDALAAAAQELGTRTKRDTVNAALREVVERNARLRALHELQELTAEGALDIEVLLDKSARRGGIGR
>NZ_CP014485.1|WP_008411247.1|3940820_3941228_-|PIN-domain-nuclease
MSVPDYLIDTSALVRVLQRRVPREWEHRIGAGLVSLCDLTELELLYSARSTSDRDAIRDRLSLFTWCPMPDGVFRRARTVQALLTDKGEHRSAGAVDLLLAATAEQSGLTLLHHDRDFETVARATGQPVRMIDLL
>NZ_CP014485.1|WP_018470082.1|3940307_3940766_-|DUF1992-domain-containing-protein
MTERKPADVSHEDWVEHQIRQAERRGEFAELPGRGKPLPGNEVEYDALWWVKAKMRREGLGQERPADGAGSLVAVCRRDAEELPAVLARIEDEAEVRRRVGELNKRITDLHLMPPPGPPLGIPRFKVDEVVREWRRARQLAARGRPGGTGRG
>NZ_CP014485.1|WP_061404660.1|3939587_3940286_+|type-1-glutamine-amidotransferase-domain-containing-protein
MATPTNRILIIVTSAGEYESAGYRTGLWLGELTHFYDVAEAAGFGLTIASVDGGRVPIDPESLAHDVLADQGTAERYADRTFMNLLEDTVAVADVRPEEYDAIYLTGGHGTMFDFPRSKALGELVAAFHDEGRVVSAVCHGPCGLLETTLADGRPLLRGREVTGFSWPEEELAQRADAVPFSLEERLRALGASYSVAEEPFAPYVVEDGLLITGQNPASATPVAEAVVRALH
>NZ_CP014485.1|WP_008411241.1|3939118_3939487_+|hypothetical-protein
MSGWMWWGLAFMLLGGGSWIGESVRSALKARHTRKLELQRAETERQRALDAANRPPEPICGCTHHLAKHDKQGTCHERVQAPVEWDADRKPVKFEERPCNCQQYVGPEPLGTVYAPEITDRG
>NZ_CP014485.1|WP_061404659.1|3938185_3939028_+|alpha/beta-hydrolase
MPQLELSAGVVDYEDTGGNGPVVVLLHGVAMDASLWDEVVPGLSGEYRCVRPVLPLGGHRRPMRAGADLSVPGVARLVAEVLEQLDLCRVTLVLNDWGGAQALFALGLGERIGRLVLTSCEAFDNYPPGLPGRNLVAAARLPGGLAAAFGLLRLRPARRLPMTWGRMSLRPVPARLMDGWLRPAQTSPEIRRDLRAYLLGVPPREELLRWAEALREFEGPALVAWAAEDKVMPVEHGRRLAALLPRAAYVEIAGSRTLIPVDQPAELLAHLRDFLARTDP
>NZ_CP014485.1|WP_031178789.1|3937616_3938090_+|nuclear-transport-factor-2-family-protein
MDTDLTDPVERMLAERACERLIVEFGQRLDLGDPGDVAELFTEDAVWEWPAGERRIEGREPLRAYFAGRPADRLSRRVASNILVTVTSPDTATATSYFTTYRVDGHTGGPFPARPPVQVGHYEDTFHRAGGRWRLAHRTLFLAFAGPTDRLPAVGRG
>NZ_CP014485.1|WP_010644913.1|3936958_3937507_+|winged-helix-turn-helix-transcriptional-regulator
MPENASVAEPPDGIDVDVDAVTGAVLTASRLLVAISARSLAAVGDRVTLPQFRMLVVLSVRGPTRLVTLAEALGVAPSTAMRMVDRLIAAGLAERQANPGNRRETSLYLTDAGLRTVREVTDRRRAEIAGVVARLEPARRADLVAALHAFNEAGGEPLAPTGAADTHPLGWGGDPAGPSPRG
>NZ_CP014485.1|WP_015507620.1|3945674_3946709_-|hypothetical-protein
MTATLTPAGRADAPASAARDRRAALPRAVLRLHRTALVVGAVLVGLFTLLLLGSLLWRSAYSPAEVAACGTGSGCPGLNAYETAHTVYWSLLNQSQNVLLLVPLVIAAYAAGPLTARERELGTHHLLWTQSAASPVRWLRSTLALGSVAVAVGAVFLVMVFRTAVAPMEGVWGFGGWEPGGYVGSGPVLVAYCLLGLAFGVCAGTLIGRALPAIFAGVAGTGLVLLAAGVARPWLWPASTLVAPFTRDRKAWPSPGDGAWTADAAVRGQWLVTGDGARIDPESCYTVPGGIEGCGVRAGAETWLVEFHPLSHRLPTQLVESGLVLLLAVLAAGAAFLVLRRRTP
>NZ_CP014485.1|WP_003949078.1|3946705_3947629_-|ABC-transporter-ATP-binding-protein
MTDTDTAIEARGLGKRFGRRNALDACSFRLPAGRICALVGPNGAGKSTLLTLAAGLARPSGGELRVLGTTPAEARREIAYVAQDKALFPQLTVADTLRLGADLNPGRWDQEAAERIVHGDGAESALDPYAKVRGLSGGQRTRVALALALGKRPALLLLDEPVSDLDPLARHQLMGTLLAEAAEHGTTVVMSSHILGELAGACDFLLLLGGGRVRMAGPADDLTAVHRLVTGPGGAAELAPHTVIESRPHGRGQSALIRPEGPVGPGWECEEPSLEDVLLAHLRNPSAPALLAPEATVRDLAGTGVQA
>NZ_CP014485.1|WP_030306898.1|3947663_3948671_-|ABC-transporter
MSTTLNRATGPGTSAPSSPSFRTLARVVLRLHRGALLTWVAVVVLVGAGLVWLRWVGASVVLPGPLECWVGPGCGPQETVQESEMTHHIFWLDWVSVLLLALPVAVAAWAGAALTGAEQERGTAALAWTQSVSPRRWIAVKWAVAGGVLTAGASSLVLLFVWARSVPYMDGSPLDDWTDWLTFSASGPVAPALFLLALTLGAYAGLLLRRSLAALAVSAGAMFGVVQGLPLLIPHLWPTERIFGWKVTAAPARAWVLSESALDAQGRPVSMSDCQYGKESLVRQCAEAKGIEGVETLFHPASHAAPLHLAETALILALTAALAFAALRLLRRRTP
>NZ_CP014485.1|WP_003949076.1|3948667_3949057_-|GntR-family-transcriptional-regulator
MIAYRIDRRSGVATYLQIVQQTRQALRLGLLEPGDKLPTAREVVEATAVNPNTVLKAYRELEREGLVEARRGLGTFVRRTLGPDADTGPLQAELAEWAARARKAGLGREDVAALCTAVLDSTYPEGEDR
>NZ_CP014485.1|WP_061404661.1|3949160_3950435_-|sigma-70-family-RNA-polymerase-sigma-factor
MRRPRPGAGVEHLLRTEAPQVLGALTRRFGRFDIAEDAVQEALIVAGQRWPAEGVPQDPRSWLIRVGYRRMVDLLRAEQARHRREQEVGRTELALGTPERRAAPTGSTDDSLTLLLLCCHPRLSPVSQVALTLRAVGGLTTAEIARAYGTSEATMGTRISRAKQQLVRDGARFVPATDADRRERTEAVMRVLYLIFNEGYTASSGESLARRDLSEEAVRLARLLHAADPDNAEAAGLLALMLLIESRHGARTDADGALVPLESQDRTRWDQELIREGTRLLDAVWDPRGTGTGPYQFQAAIAALHAEAPAPELTDWPRIAMLYLWLERLTPTAPVRLSRVVAVARAFGPTRGLTLLDTLCRRHSLDRDPLVRHHERAVRAHLTRMTGDTAGAAALYREAATLTANGAERRYLLTEAEQADKATT
>NZ_CP014485.1|WP_008405085.1|3950469_3950841_-|hypothetical-protein
MKYLLLGYTSADGWDAATAGSPTEEALEAFAAYQRFEEELTASGELVSTEGLGHPAVSTTVRPTAEGVTATDGPFAELKEVLASFAVIDVSGQERAVEIAARIVAVLGEPVEIRPVMGADFAA
>NZ_CP014485.1|WP_003949073.1|3951068_3951512_+|hypothetical-protein
MSETETETAPQQPTPELRALDRLTGNWKVTGGAEGTVRYEWMAGGFFLLQHVDLVQFGRPVTGMEIIGNLRPFGEPTGPDVASRYYDSQGNTFDYVYELDGDTLTIWAGAKDSPAYFRGTFTPDGTTMTGDWIYPGGGGYSSTMTRV
>NZ_CP014485.1|WP_008405080.1|3951764_3952139_-|hypothetical-protein
MTAGAVEYLAETYGGDARSSVFLGGIITPTRRLALRWLRGQARRIADALDPYPYVRWAPPGALRRVPAADRDAPGALRGWQASTECQDAALHALAAGGPYAFLTHDATCWYRLTVHPLPGPVTP
>NZ_CP014485.1|WP_003949070.1|3952135_3952348_-|hypothetical-protein
MRGGAAGVRGAEPEGGEAEFNPLLFPPCACPRHRGAEGEAGEGEESAVLRQLRARVAEENGARRWVRGQG
>NZ_CP014485.1|WP_003949068.1|3952634_3953468_+|helix-turn-helix-transcriptional-regulator
MTVELSPDDATDPGLSPLRNFGNEVMLERTRMNMSRVELGRAVACGESLVAKIERGDRVPQREFAEGCDQVFPHGNGRFMRLWRLALRYAYPPWFWPYVALEKKATGLRMFNPVVAPGIVQTRSYATAILKEGRPKGLEDLVTARLERQQILQREEPTGLWLVLHERVLRNVVGSEEIMREQLLRLLQIAETSTHRVQIIRDEGRYRGPVGAAPFVLMSFEEGADVVHVDGFPRGYVLAEQDEVADAEDAYDLLRALAMPLEESAELINSVLKECYS

Crispr_ID: NZ_CP014485_23

• CRISPR_ID: NZ_CP014485_23
• CRISPR_location: 3996940-3997051
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP014485_23

Consensus_repeat	Method
ACAGCGACAACGGCGGCGCCTGCGTCGAGGT	CRISPRCasFinder

spacers of NZ_CP014485_23

>23.1|3996971|50|NZ_CP014485|CRISPRCasFinder
CCACATCCCCCCGGCCCTCGATGCCTCCCCGGACTGGTTCAAGTCCTCGC

CRISPR arrays and Neighbor proteins around NZ_CP014485_23

CRISPR arrays

The CRISPR arrays of NZ_CP014485_23

>merge|NZ_CP014485|23|3996940-3997051|CRISPRCasFinder
ACAGCGACAACGGCGGCGCCTGCGTCGAGGTCCACATCCCCCCGGCCCTCGATGCCTCCCCGGACTGGTTCAAGTCCTCGCACAGCAACAACGGCGGCGCCTGCGTCGAGGT

>NZ_CP014485|23|18|3996940-3997051|CRISPRCasFinder
ACAGCGACAACGGCGGCGCCTGCGTCGAGGT	CCACATCCCCCCGGCCCTCGATGCCTCCCCGGACTGGTTCAAGTCCTCGC
ACAGCAACAACGGCGGCGCCTGCGTCGAGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003949019.1|4000747_4001533_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|367243
NZ_CP014485.1|WP_061404676.1|3998901_3999645_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|272861
NZ_CP014485.1|WP_008415453.1|4002213_4002855_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP014485.1|WP_018895042.1|3996543_3996750_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014485.1|WP_018470044.1|3992037_3993042_+|asparaginase	unknown	unknown	gnl|CDD|377601
NZ_CP014485.1|WP_061404679.1|4004771_4005443_-|haloacid-dehalogenase-type-II	unknown	unknown	gnl|CDD|319787
NZ_CP014485.1|WP_061404677.1|3999637_4000642_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|130256
NZ_CP014485.1|WP_008415465.1|3995707_3996547_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP014485.1|WP_061404678.1|4003264_4004278_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP014485.1|WP_037846083.1|3993064_3993415_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133388
NZ_CP014485.1|WP_018895045.1|3995140_3995362_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008415428.1|4007140_4007995_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP014485.1|WP_049978445.1|3991127_3991937_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003949028.1|3994386_3995124_+|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NZ_CP014485.1|WP_018470042.1|3993632_3994268_+|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|376808
NZ_CP014485.1|WP_003949015.1|4004394_4004754_+|VOC-family-protein	unknown	unknown	gnl|CDD|319922
NZ_CP014485.1|WP_061405503.1|4005670_4007110_+|rifampin-monooxygenase	unknown	unknown	gnl|CDD|235870
NZ_CP014485.1|WP_049978468.1|3995358_3995538_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003949033.1|3990509_3990935_-|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl|CDD|235383
NZ_CP014485.1|WP_061404674.1|3998095_3998305_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_061404678.1|4003264_4004278_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	2.3e-34	114.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008415465.1|3995707_3996547_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.26764e-06
NZ_CP014485.1|WP_061404676.1|3998901_3999645_-|ABC-transporter-permease	gnl|CDD|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	1.53911e-15
NZ_CP014485.1|WP_018895042.1|3996543_3996750_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.71688e-19
NZ_CP014485.1|WP_018470044.1|3992037_3993042_+|asparaginase	gnl|CDD|377601	pfam06089, Asparaginase_II, L-asparaginase II. This family consists of several bacterial L-asparaginase II proteins. L-asparaginase (EC:3.5.1.1) catalyzes the hydrolysis of L-asparagine to L-aspartate and ammonium. Rhizobium etli possesses two asparaginases: asparaginase I, which is thermostable and constitutive, and asparaginase II, which is thermolabile, induced by asparagine and repressed by the carbon source.	9.48308e-142
NZ_CP014485.1|WP_061404679.1|4004771_4005443_-|haloacid-dehalogenase-type-II	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.21008e-42
NZ_CP014485.1|WP_061404677.1|3999637_4000642_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.3924e-108
NZ_CP014485.1|WP_008415453.1|4002213_4002855_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.25283e-26
NZ_CP014485.1|WP_061404678.1|4003264_4004278_-|WYL-domain-containing-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	4.22291e-28
NZ_CP014485.1|WP_037846083.1|3993064_3993415_-|MerR-family-transcriptional-regulator	gnl|CDD|133388	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 3). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.37082e-36
NZ_CP014485.1|WP_003949028.1|3994386_3995124_+|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	1.68216e-10
NZ_CP014485.1|WP_018470042.1|3993632_3994268_+|NAD(P)H-dependent-oxidoreductase	gnl|CDD|376808	pfam02525, Flavodoxin_2, Flavodoxin-like fold. This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.	1.01987e-12
NZ_CP014485.1|WP_003949015.1|4004394_4004754_+|VOC-family-protein	gnl|CDD|319922	cd07261, EhpR_like, phenazine resistance protein, EhpR. Phenazine resistance protein (EhpR) in Enterobacter agglomerans confers resistance by binding D-alanyl-griseoluteic acid and acting as a chaperone involved in exporting the antibiotic rather than by altering it chemically. EhpR is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.	3.42669e-32
NZ_CP014485.1|WP_061405503.1|4005670_4007110_+|rifampin-monooxygenase	gnl|CDD|235870	PRK06834, PRK06834, hypothetical protein; Provisional.	7.77552e-162
NZ_CP014485.1|WP_003949019.1|4000747_4001533_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	2.83247e-11
NZ_CP014485.1|WP_003949033.1|3990509_3990935_-|D-tyrosyl-tRNA(Tyr)-deacylase	gnl|CDD|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	3.71768e-80
NZ_CP014485.1|WP_008415428.1|4007140_4007995_-|alpha/beta-fold-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.08253e-11

Protein sequences

>NZ_CP014485.1|WP_018895042.1|3996543_3996750_+|DUF397-domain-containing-protein
MTSEPHWFKSSYSNNGGVCVEVATNLVAPHGIVPVRDSKVQSGPVLTVPATAFSSFVAGVKAGTFRSA
>NZ_CP014485.1|WP_008415465.1|3995707_3996547_+|helix-turn-helix-domain-containing-protein
MVNRKELNPEASPHAAFGAKLRVVREAQGLTQDQLGSAMGYTCGHISSVETGRKVPTLRFSRQVDQALGTANTEDSFERQWREIRQGSLLEGAPEYMGCEARSAEIRLYEVGVVPGLLQTPEYALTLAEGAVLRGSITEEQAAERVQMIADRQEALSRRSPPMVFVVLDESCLRRPVGEPTIMNAQLEYLMEFADRPNTMVQVAPFDLGARRPFDLPIYILTMPDRQLMSYAESAQRGHLDRESTSVLPLLTAYHQLQALALSQAASVAMISQLRKGTP
>NZ_CP014485.1|WP_049978468.1|3995358_3995538_-|hypothetical-protein
MSAVDSPHGKGDQPCSTCQSWKLAEAVANGEQDYSRATDCRVLLKRHRESAECGAGGEG
>NZ_CP014485.1|WP_018895045.1|3995140_3995362_-|hypothetical-protein
MSAGYEPPGKAYREFDPLRFPPCACEGCRRRAALESQAPPPTEPVPAPEQPRYVRCPMLGCGRLHPALPDDAG
>NZ_CP014485.1|WP_003949028.1|3994386_3995124_+|HAD-family-phosphatase
MTSSTHPPEPTADELAGLRDLVAAAKTVIVGFDGPLCRLYDPLTARTAADSLTALLAEHGVPAGDVPGRTPLALLRSLTLGALDDDPALSTALDELLTGSEVAATLTARPAPYADNLVRTWSAVGTRLAVATGHSADAVHAYLAGRGLTACFGPHVYGRTDGLTHLGHDAPPRALAALGADPAEALVLGSTPEDLRAARDAGAPFLGYARDLPAYDRLRAAGAPLVTGTLEPVRQAVWELNLPRR
>NZ_CP014485.1|WP_018470042.1|3993632_3994268_+|NAD(P)H-dependent-oxidoreductase
MTSFPTQAPDQDQNQDRSFLFVLGSSRPDGNTAQLARAAAEHLPAAYGRRWIDLNDLDLPDFQDGRHEGERWQPGEAEATLHEATVAATDIVIATPLYWYSFSAQTKRYLDYWSGWLTLPGSDFAARMAGRRLWGVTVMADRDEVVAGGLDTSLHHTAAYLKMGYGGILLGNGSRPGQVAVDERAQRRAKTFFAGPTPLARFPHEEAAEAA
>NZ_CP014485.1|WP_037846083.1|3993064_3993415_-|MerR-family-transcriptional-regulator
MLIGELSRRTGVSRRLLRYYEDQGLLQAARGTNGYRSYAEDAVAVVGRIRFLLDAGLTTEVIQAVLPCVDQDTFDSGIDWCGELRDLLAGELAALDERLNCLQERRTSLAGLLGQG
>NZ_CP014485.1|WP_018470044.1|3992037_3993042_+|asparaginase
MSPAQPVPPRPAADAPAPPPAGPSPVLAEVVRSGFVEGVHRGSVVVLEADGSVAWSLGEPDRPVFPRSANKPMQAAAILRAGLDLAGERLALAAASHSGEPFHLELAERMLTEFGLSADALQCPPDLPLDPVEAEQYLASGQVRRPLTMNCSGKHAAMLAACARNGWPLDSYLDPAHPLQLLVRETVEAAAGEPVAALGTDGCGAPLMALTLPGLARAFAAFVRAEPGTPERRVADAMRAHPEYVAGTRRPDTWLMRALPGALSKMGAEAVQAVALPDGRALAFKVDDGATRALGPVLARLLERLGYAGETATRIGSAPLMGGAVRVGEIRAAF
>NZ_CP014485.1|WP_049978445.1|3991127_3991937_+|hypothetical-protein
MSTSSTSSTPTTAGTGRLAPEQRSGGVYGSARPPTQRTDSPAPGAGLSATGEPTRDLVLLSLAELRTVRRTALRDEGDLSYVRRILQGRLDILRAEAATRRAERTAAAGSDSASGAAQAGSPRPAGATGAGEGTVSGSGSGSGLALGFGAGLTGAGRRLVVGAPVVARLSQILADAPTRHRASARHVTVSVPQGEESRRLAAEMLSEVELSDLSALTDEELETATARLGRYELQVSRRRAQLQRTADACGAEITRRYREGEAQVDDLLA
>NZ_CP014485.1|WP_003949033.1|3990509_3990935_-|D-tyrosyl-tRNA(Tyr)-deacylase
MRAVVQRVDGASVVVDGETVGEISGEGLCVLVGVTHDDTGEKAAQLARKLWSLRILNEERSCSDTGAPLLVISQFTLYGDARKGRRPTWSAAAPGPVAEPLVEAVVAHLRELGATVATGRFGAKMRVGLTNDGPFTVLLEV
>NZ_CP014485.1|WP_061404674.1|3998095_3998305_-|hypothetical-protein
MTTIILLLVMGITLILSRNIFARFASSQNTPFGRANAKHPKATSMGPVAIGSIMIIAAILGIFGVLEPQ
>NZ_CP014485.1|WP_061404676.1|3998901_3999645_-|ABC-transporter-permease
MSEALTLAGRCLRMNRRDPEALFMAILLPVALMLVFVYFFGGAIDTGSAYVTYVVPGLLVLCAGYGSAGTAMRVTEDMRTGVVDRLRSMGVTGTPMLAGHVAASVVRNILATAMVLSVALLIGFRPAADPLAWLAAAGLLLAYLVAVSWLAAGVGLLARTPEGASGFTFFLMFLPYPSSAFVPIETMPTWLHGFAEHQPVTPLIESLRALLLDEPLGSAPWTALAWCGGILLVAAAASNALFRRRTR
>NZ_CP014485.1|WP_061404677.1|3999637_4000642_-|ATP-binding-cassette-domain-containing-protein
MRQPPHAAVEVQGLSKSYGDHAVLRSVDLRVEQGGVLALLGPNGAGKTTTVRVLTTLTDPDAGSVRVAGYDVVTERRRAQRAISLTGQFAAVDETQTGAENLWTTARLAGLTRAAARRRAAELLERFALTDAGGRLVRTYSGGMRRRLDLAAGLVGEPRVLFLDEPTTGLDPRSRRQLWEVVRELAAAGTAVLLTTQYLEEADQLADRVAVLHGGRIAAEGTPEELKASAGQTVLEVTAADAAAFARLEARTPHPVAHRSPDTLALSFPTRGDARHLRTLLDELDPGRDEITAFHVRQATLDDVFMALTGAPATETTGTTDTTGTTDAKEPSHV
>NZ_CP014485.1|WP_003949019.1|4000747_4001533_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MAPPPPERRDPADETGLPASVEAAWGLRGRPTKGPRPGIGVERIVDAAVKLAATEGLQAVSMGRVAKELGASTMSLYRYVAAKDELFILMQEAATGLPPEDAPPPSAGWRARLAWFGHAYRGVLEANLWLLHIPISSPPATPNSVAWMEAGLDALDGTGLDEATKLGVMMLISGYVRSQAGLMADLTEAMRRSGRSAEDTHRQYIHTLTRLADQRGPEAFPAVRRLLASQVLGEGDDADADFDWGLHRVLDGVQVLIEGRA
>NZ_CP014485.1|WP_008415453.1|4002213_4002855_-|histidine-phosphatase-family-protein
MTSTAATGMASRTLYLARHGDAPGEGGLSAQGRRQAAFLGERLRGVPLSAIHHGPQARARETAEIVAAQRDDEEPVPRACDSAGDYVPYLPERREVASGLPEATWEWLLQLPERERLPGPELARDALRRFTGAVPGGVARHELVVTHNFVIGWLVREALDAPDWRWIGLHHANAALSIIHYAPEGPSSLIVYNDIRHLPEELRWTGFPPGLRV
>NZ_CP014485.1|WP_061404678.1|4003264_4004278_-|WYL-domain-containing-protein
MTPDRFFALLLALQTRRDPVTTTDLAAETGVSVRTVLRDLRWLQDAGFPVLVERGRWGGVTLLPGGALDTARLTPAERDQLALHGLDDRQRHQLGAAADGRRAREKVAARASGAAGPPLPLSAVVTTDSRPWFWSGAQGLEPSALVGDVRRGVRLRIRYRRAAESAPAWQLVDPYGLLAKAGRWYLVADRSGTPRLYSLERLTDWRPTAAPRRLRPGISLADAVAELTTGWETSADLRIHGLLAARHAERAQRILGSRVTVHRPGEGPALTPSPGPDQVALTLSCRNLEEVRQLLPFGADLLITDPPEARTRLRELAAEVVGQYVEQDEGAEGAGPS
>NZ_CP014485.1|WP_003949015.1|4004394_4004754_+|VOC-family-protein
MTRPNMFIVHVSDAPESARFYGDLFAMEPVFEAPRFIAFELGGGVQLALWSGAAEDLSGPRTSEVCLNLDGAPASVDARHEEWTAKGVTIVEEPHDAVFGRTFVAADPDGNLIRVAPFD
>NZ_CP014485.1|WP_061404679.1|4004771_4005443_-|haloacid-dehalogenase-type-II
MSRRPDPQFVTFDMYGTLTDFPVGAAAEKTIEAISSAGQRDVFRRRFAAYQLDESMGDWRPYDELIARAFERACRSAGIPFRPADPAAVFDQIPTWGPHPDVPGPLARLAARHPLVILSNASDQHASRNAALLGAPLHAVYTAEQARAYKPRLGAFEYLYAQLGCRPEDTLHVSASPRYDLQSATDLGVRETVYLNRGYEPSAPHCHAYEVTTLAGVAELLGV
>NZ_CP014485.1|WP_061405503.1|4005670_4007110_+|rifampin-monooxygenase
MIDVLVVGAGPTGLMLAAELRLHGVRTVVVEKDTEPTGHSRAQGLHVRSTEVMDQRGLLDQFLERGRQFRVGGFFAGLGPAWPEGMDTAHSYVLAIPQAETERLLAEHATGLGAEFRRGCALTGLEQDADGVTAGLADGTRLRARYLVGCDGGRSTVRKLLGTPFPGEPSRVDTLLGDVALTATPEELAAVTAEVRKTHLRYGAMPLGEGRYRVIVPDEGASEDRAAPPTLDHLRARLRVVGGTDFGAHDPRWISRFGDATRQAERYRTGRVLLAGDAAHVHPPTGGQGLNLGVQDAFNLGWKLAAEVNGWAPDGLLDSYHAERHPVGAAVLDNTRAQTELMNPGPGQRALRRLVAELMEFEEVNRHLIEKITAVSVRYDLGGGHPLVGRRLRDVRLGRGRLYELTHAGRGLLLDPAGRLSAGGWADRVDHVVDTGPELDELDVPAALLRPDGHVAWVGDDQEGLAPALKRWFGEPAAG
>NZ_CP014485.1|WP_008415428.1|4007140_4007995_-|alpha/beta-fold-hydrolase
MPLSPTFVLVHGAFANSFSFAPLQAELGLLGHRSVAVDLPGHGFEATFPASYQAPQDFAALAAEPGAIKGVTLADNAARVIEALERARRNGPTVLVGHSRGGATITAVANARPDLIDRLVYVSAWCPVDLPVGDYYAEPEMASVDPMAFAPSLLGNPAELGLLRTNFRTSDPAALATFKEAFGADLTDDEFRTFLNTFQPDESLDAGTEADRAQAATWGTLPRTYVRLADDTSLTPAAQDRMIREADALTPGNPFDVHTLDGSHLRWLVHPGPAAAVLAGLAAG

Crispr_ID: NZ_CP014485_24

• CRISPR_ID: NZ_CP014485_24
• CRISPR_location: 4002099-4002185
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP014485_24

Consensus_repeat	Method
AGCCCGGCCGGCGCTTGAGGCCA	CRISPRCasFinder

spacers of NZ_CP014485_24

>24.1|4002122|41|NZ_CP014485|CRISPRCasFinder
ATCGGTGACCGGCACGGTCGAGACGGAGCCCGGCAACCCAC

CRISPR arrays and Neighbor proteins around NZ_CP014485_24

CRISPR arrays

The CRISPR arrays of NZ_CP014485_24

>merge|NZ_CP014485|24|4002099-4002185|CRISPRCasFinder
AGCCCGGCCGGCGCTTGAGGCCAATCGGTGACCGGCACGGTCGAGACGGAGCCCGGCAACCCACAGCCCGGCTGGCGCTTGAGGCCA

>NZ_CP014485|24|19|4002099-4002185|CRISPRCasFinder
AGCCCGGCCGGCGCTTGAGGCCA	ATCGGTGACCGGCACGGTCGAGACGGAGCCCGGCAACCCAC
AGCCCGGCTGGCGCTTGAGGCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061404673.1|3996902_3997193_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014485.1|WP_003949019.1|4000747_4001533_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|367243
NZ_CP014485.1|WP_061404676.1|3998901_3999645_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|272861
NZ_CP014485.1|WP_061404682.1|4009612_4010410_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_018895042.1|3996543_3996750_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP014485.1|WP_061404680.1|4008089_4008842_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP014485.1|WP_061404679.1|4004771_4005443_-|haloacid-dehalogenase-type-II	unknown	unknown	gnl|CDD|319787
NZ_CP014485.1|WP_061404683.1|4010458_4010836_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404677.1|3999637_4000642_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|130256
NZ_CP014485.1|WP_008415465.1|3995707_3996547_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP014485.1|WP_061404678.1|4003264_4004278_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP014485.1|WP_018895045.1|3995140_3995362_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008415428.1|4007140_4007995_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP014485.1|WP_061404681.1|4008957_4009596_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|274422
NZ_CP014485.1|WP_003949028.1|3994386_3995124_+|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NZ_CP014485.1|WP_008415453.1|4002213_4002855_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP014485.1|WP_003949015.1|4004394_4004754_+|VOC-family-protein	unknown	unknown	gnl|CDD|319922
NZ_CP014485.1|WP_061405503.1|4005670_4007110_+|rifampin-monooxygenase	unknown	unknown	gnl|CDD|235870
NZ_CP014485.1|WP_049978468.1|3995358_3995538_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404674.1|3998095_3998305_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_061404678.1|4003264_4004278_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	2.3e-34	114.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_061404673.1|3996902_3997193_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.34228e-20
NZ_CP014485.1|WP_061404681.1|4008957_4009596_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	1.66407e-22
NZ_CP014485.1|WP_061404676.1|3998901_3999645_-|ABC-transporter-permease	gnl|CDD|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	1.53911e-15
NZ_CP014485.1|WP_018895042.1|3996543_3996750_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.71688e-19
NZ_CP014485.1|WP_061404679.1|4004771_4005443_-|haloacid-dehalogenase-type-II	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.21008e-42
NZ_CP014485.1|WP_061404677.1|3999637_4000642_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.3924e-108
NZ_CP014485.1|WP_008415453.1|4002213_4002855_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.25283e-26
NZ_CP014485.1|WP_061404678.1|4003264_4004278_-|WYL-domain-containing-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	4.22291e-28
NZ_CP014485.1|WP_061404680.1|4008089_4008842_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.86246e-18
NZ_CP014485.1|WP_003949028.1|3994386_3995124_+|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	1.68216e-10
NZ_CP014485.1|WP_008415465.1|3995707_3996547_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.26764e-06
NZ_CP014485.1|WP_003949015.1|4004394_4004754_+|VOC-family-protein	gnl|CDD|319922	cd07261, EhpR_like, phenazine resistance protein, EhpR. Phenazine resistance protein (EhpR) in Enterobacter agglomerans confers resistance by binding D-alanyl-griseoluteic acid and acting as a chaperone involved in exporting the antibiotic rather than by altering it chemically. EhpR is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.	3.42669e-32
NZ_CP014485.1|WP_061405503.1|4005670_4007110_+|rifampin-monooxygenase	gnl|CDD|235870	PRK06834, PRK06834, hypothetical protein; Provisional.	7.77552e-162
NZ_CP014485.1|WP_003949019.1|4000747_4001533_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	2.83247e-11
NZ_CP014485.1|WP_008415428.1|4007140_4007995_-|alpha/beta-fold-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.08253e-11

Protein sequences

>NZ_CP014485.1|WP_003949019.1|4000747_4001533_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MAPPPPERRDPADETGLPASVEAAWGLRGRPTKGPRPGIGVERIVDAAVKLAATEGLQAVSMGRVAKELGASTMSLYRYVAAKDELFILMQEAATGLPPEDAPPPSAGWRARLAWFGHAYRGVLEANLWLLHIPISSPPATPNSVAWMEAGLDALDGTGLDEATKLGVMMLISGYVRSQAGLMADLTEAMRRSGRSAEDTHRQYIHTLTRLADQRGPEAFPAVRRLLASQVLGEGDDADADFDWGLHRVLDGVQVLIEGRA
>NZ_CP014485.1|WP_061404677.1|3999637_4000642_-|ATP-binding-cassette-domain-containing-protein
MRQPPHAAVEVQGLSKSYGDHAVLRSVDLRVEQGGVLALLGPNGAGKTTTVRVLTTLTDPDAGSVRVAGYDVVTERRRAQRAISLTGQFAAVDETQTGAENLWTTARLAGLTRAAARRRAAELLERFALTDAGGRLVRTYSGGMRRRLDLAAGLVGEPRVLFLDEPTTGLDPRSRRQLWEVVRELAAAGTAVLLTTQYLEEADQLADRVAVLHGGRIAAEGTPEELKASAGQTVLEVTAADAAAFARLEARTPHPVAHRSPDTLALSFPTRGDARHLRTLLDELDPGRDEITAFHVRQATLDDVFMALTGAPATETTGTTDTTGTTDAKEPSHV
>NZ_CP014485.1|WP_061404676.1|3998901_3999645_-|ABC-transporter-permease
MSEALTLAGRCLRMNRRDPEALFMAILLPVALMLVFVYFFGGAIDTGSAYVTYVVPGLLVLCAGYGSAGTAMRVTEDMRTGVVDRLRSMGVTGTPMLAGHVAASVVRNILATAMVLSVALLIGFRPAADPLAWLAAAGLLLAYLVAVSWLAAGVGLLARTPEGASGFTFFLMFLPYPSSAFVPIETMPTWLHGFAEHQPVTPLIESLRALLLDEPLGSAPWTALAWCGGILLVAAAASNALFRRRTR
>NZ_CP014485.1|WP_061404674.1|3998095_3998305_-|hypothetical-protein
MTTIILLLVMGITLILSRNIFARFASSQNTPFGRANAKHPKATSMGPVAIGSIMIIAAILGIFGVLEPQ
>NZ_CP014485.1|WP_061404673.1|3996902_3997193_+|DUF397-domain-containing-protein
MTPNSPYWRKSSYSDNGGACVEVHIPPALDASPDWFKSSHSNNGGACVEVAANLVPTHDLVPVRDSKTPSGPVLTFPATAFSSFVAGIRAGEFRSA
>NZ_CP014485.1|WP_018895042.1|3996543_3996750_+|DUF397-domain-containing-protein
MTSEPHWFKSSYSNNGGVCVEVATNLVAPHGIVPVRDSKVQSGPVLTVPATAFSSFVAGVKAGTFRSA
>NZ_CP014485.1|WP_008415465.1|3995707_3996547_+|helix-turn-helix-domain-containing-protein
MVNRKELNPEASPHAAFGAKLRVVREAQGLTQDQLGSAMGYTCGHISSVETGRKVPTLRFSRQVDQALGTANTEDSFERQWREIRQGSLLEGAPEYMGCEARSAEIRLYEVGVVPGLLQTPEYALTLAEGAVLRGSITEEQAAERVQMIADRQEALSRRSPPMVFVVLDESCLRRPVGEPTIMNAQLEYLMEFADRPNTMVQVAPFDLGARRPFDLPIYILTMPDRQLMSYAESAQRGHLDRESTSVLPLLTAYHQLQALALSQAASVAMISQLRKGTP
>NZ_CP014485.1|WP_049978468.1|3995358_3995538_-|hypothetical-protein
MSAVDSPHGKGDQPCSTCQSWKLAEAVANGEQDYSRATDCRVLLKRHRESAECGAGGEG
>NZ_CP014485.1|WP_018895045.1|3995140_3995362_-|hypothetical-protein
MSAGYEPPGKAYREFDPLRFPPCACEGCRRRAALESQAPPPTEPVPAPEQPRYVRCPMLGCGRLHPALPDDAG
>NZ_CP014485.1|WP_003949028.1|3994386_3995124_+|HAD-family-phosphatase
MTSSTHPPEPTADELAGLRDLVAAAKTVIVGFDGPLCRLYDPLTARTAADSLTALLAEHGVPAGDVPGRTPLALLRSLTLGALDDDPALSTALDELLTGSEVAATLTARPAPYADNLVRTWSAVGTRLAVATGHSADAVHAYLAGRGLTACFGPHVYGRTDGLTHLGHDAPPRALAALGADPAEALVLGSTPEDLRAARDAGAPFLGYARDLPAYDRLRAAGAPLVTGTLEPVRQAVWELNLPRR
>NZ_CP014485.1|WP_008415453.1|4002213_4002855_-|histidine-phosphatase-family-protein
MTSTAATGMASRTLYLARHGDAPGEGGLSAQGRRQAAFLGERLRGVPLSAIHHGPQARARETAEIVAAQRDDEEPVPRACDSAGDYVPYLPERREVASGLPEATWEWLLQLPERERLPGPELARDALRRFTGAVPGGVARHELVVTHNFVIGWLVREALDAPDWRWIGLHHANAALSIIHYAPEGPSSLIVYNDIRHLPEELRWTGFPPGLRV
>NZ_CP014485.1|WP_061404678.1|4003264_4004278_-|WYL-domain-containing-protein
MTPDRFFALLLALQTRRDPVTTTDLAAETGVSVRTVLRDLRWLQDAGFPVLVERGRWGGVTLLPGGALDTARLTPAERDQLALHGLDDRQRHQLGAAADGRRAREKVAARASGAAGPPLPLSAVVTTDSRPWFWSGAQGLEPSALVGDVRRGVRLRIRYRRAAESAPAWQLVDPYGLLAKAGRWYLVADRSGTPRLYSLERLTDWRPTAAPRRLRPGISLADAVAELTTGWETSADLRIHGLLAARHAERAQRILGSRVTVHRPGEGPALTPSPGPDQVALTLSCRNLEEVRQLLPFGADLLITDPPEARTRLRELAAEVVGQYVEQDEGAEGAGPS
>NZ_CP014485.1|WP_003949015.1|4004394_4004754_+|VOC-family-protein
MTRPNMFIVHVSDAPESARFYGDLFAMEPVFEAPRFIAFELGGGVQLALWSGAAEDLSGPRTSEVCLNLDGAPASVDARHEEWTAKGVTIVEEPHDAVFGRTFVAADPDGNLIRVAPFD
>NZ_CP014485.1|WP_061404679.1|4004771_4005443_-|haloacid-dehalogenase-type-II
MSRRPDPQFVTFDMYGTLTDFPVGAAAEKTIEAISSAGQRDVFRRRFAAYQLDESMGDWRPYDELIARAFERACRSAGIPFRPADPAAVFDQIPTWGPHPDVPGPLARLAARHPLVILSNASDQHASRNAALLGAPLHAVYTAEQARAYKPRLGAFEYLYAQLGCRPEDTLHVSASPRYDLQSATDLGVRETVYLNRGYEPSAPHCHAYEVTTLAGVAELLGV
>NZ_CP014485.1|WP_061405503.1|4005670_4007110_+|rifampin-monooxygenase
MIDVLVVGAGPTGLMLAAELRLHGVRTVVVEKDTEPTGHSRAQGLHVRSTEVMDQRGLLDQFLERGRQFRVGGFFAGLGPAWPEGMDTAHSYVLAIPQAETERLLAEHATGLGAEFRRGCALTGLEQDADGVTAGLADGTRLRARYLVGCDGGRSTVRKLLGTPFPGEPSRVDTLLGDVALTATPEELAAVTAEVRKTHLRYGAMPLGEGRYRVIVPDEGASEDRAAPPTLDHLRARLRVVGGTDFGAHDPRWISRFGDATRQAERYRTGRVLLAGDAAHVHPPTGGQGLNLGVQDAFNLGWKLAAEVNGWAPDGLLDSYHAERHPVGAAVLDNTRAQTELMNPGPGQRALRRLVAELMEFEEVNRHLIEKITAVSVRYDLGGGHPLVGRRLRDVRLGRGRLYELTHAGRGLLLDPAGRLSAGGWADRVDHVVDTGPELDELDVPAALLRPDGHVAWVGDDQEGLAPALKRWFGEPAAG
>NZ_CP014485.1|WP_008415428.1|4007140_4007995_-|alpha/beta-fold-hydrolase
MPLSPTFVLVHGAFANSFSFAPLQAELGLLGHRSVAVDLPGHGFEATFPASYQAPQDFAALAAEPGAIKGVTLADNAARVIEALERARRNGPTVLVGHSRGGATITAVANARPDLIDRLVYVSAWCPVDLPVGDYYAEPEMASVDPMAFAPSLLGNPAELGLLRTNFRTSDPAALATFKEAFGADLTDDEFRTFLNTFQPDESLDAGTEADRAQAATWGTLPRTYVRLADDTSLTPAAQDRMIREADALTPGNPFDVHTLDGSHLRWLVHPGPAAAVLAGLAAG
>NZ_CP014485.1|WP_061404680.1|4008089_4008842_+|class-I-SAM-dependent-methyltransferase
MADECFRHPRLAAVYDALDPDRGDLDAYVRAVREFGARRVLDIGCGTGVFALLLAARGIEVVGVDPARASLDVARAKPGADRVRWICGDATGLPPLRADLATLTANAAQEITGPDAWRATLRGAYGALRPGGHLLFETRDPARRAWEEWTPEASRHTTEIPGHGAVESWVELREVRGPLVTFRWTYVFAADGQVLTSDSTLRFRERQEIEADLAAEGFEVVEVRDAPDRPGKEFVFVARRGEGTGAGTVA
>NZ_CP014485.1|WP_061404681.1|4008957_4009596_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MTDPVWASIHAERAALAADLAGLTEEQWATRSLCSGLTVREVLAHLTASASLNAVRWMAGVIRCRFDFDRQVAVRLAEQLGATPAETLERFRSVVASTTKPPLPVVAMLGETLVHGEDIRRPLGLRRDHPVEVVTRVAAYYQGSDQVVVARSRVAGLRLVADDGPFTSGTGPLVSGPTLALVMAMTGRTACCDDLDGEGVELLRSRCGAGTV
>NZ_CP014485.1|WP_061404682.1|4009612_4010410_-|hypothetical-protein
MSLSGLSLSHWRSLDPPAARRLARQAADRAGGQVTAVETVEHLGAPLHRVRIACRGREFALIPGGEVTLGFDADGRRLPPGLEAGYAESAEQGYGYGPDLRSHLAQVLSPRRTVTVPTVLMAVEAEKLTAPPAGTPGLLAAEGLRMPSSDEWEHACGAGADTLFRWGDTCPLDRIPYGDDSGPHQQPNAFGLRIAHDTYDAELTSEPGAVHGGDGGESVCGGYGAVLAWLPLATAQRNPAMAEFVYGPDGEEMYEEFSTRPVLAL
>NZ_CP014485.1|WP_061404683.1|4010458_4010836_-|hypothetical-protein
MSRGTAGAVADGGFKIALAVGYLVGAVPLGRLLGTPVWLMAVAGVVLLIGGGVELAYTGSRSMRLYTRLMIGYDSGWVLAALAGLLVAWRGGGAGGEVWMGYQVVAQAAFAGVLIAGGSSRRGSG

Crispr_ID: NZ_CP014485_25

• CRISPR_ID: NZ_CP014485_25
• CRISPR_location: 4068001-4068296
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP014485_25

Consensus_repeat	Method
ATGGCCTCAAGCGCCGGCCGGGCTGGGA	CRT
GGCTGTCAAGG------ATGGCCTCAATCGCCGGCCGGGCTG	PILER-CR

spacers of NZ_CP014485_25

>25.1|4068029|50|NZ_CP014485|CRT
TGTGGCTGACGCCCCGCTCCTGCCTGCGGGCCTCGACAGCCCTGTCCGGG
>25.2|4068107|50|NZ_CP014485|CRT
GATGGCTGGCCTTGTCCCCTCCCTGCCGACTCCGACGGTGGCGGTCACGT
>25.3|4068185|56|NZ_CP014485|CRT
TTTGGTGTGGTTGGGCTCCGCCCCTCCGTGCCCGCCGTGACCCTGGGGGTCACCGA
>25.4|4068123|25|NZ_CP014485|PILER-CR
TCCCCTCCCTGCCGACTCCGACGGT
>25.5|4068201|79|NZ_CP014485|PILER-CR
GGGTTTGGTGTGGTTGGGCTCCGCCCCTCCGTGCCCGCCGTGACCCTGGGGGTCACCGACTGGCCTCAAGCGCCGGCCG

CRISPR arrays and Neighbor proteins around NZ_CP014485_25

CRISPR arrays

The CRISPR arrays of NZ_CP014485_25

>merge|NZ_CP014485|25|4068001-4068296|CRT,PILER-CR
ATGGCCTCAAGCGCCGGCCAGGCTGGGATGTGGCTGACGCCCCGCTCCTGCCTGCGGGCCTCGACAGCCCTGTCCGGGATGGCCTCAATCGCCGGCCGGGCTTGGAGATGGCTGGCCTTGTCCCCTCCCTGCCGACTCCGACGGTGGCGGTCACGTACGGCCTCAAGCGCCGGCCGGGCTGGGGTTTGGTGTGGTTGGGCTCCGCCCCTCCGTGCCCGCCGTGACCCTGGGGGTCACCGACTGGCCTCAAGCGCCGGCCGGGCTGGAAAAGATGGCCTCAATCGCCGGCCAGGCTG

>NZ_CP014485|25|2|4068001-4068268|CRT
ATGGCCTCAAGCGCCGGCCAGGCTGGGA	TGTGGCTGACGCCCCGCTCCTGCCTGCGGGCCTCGACAGCCCTGTCCGGG
ATGGCCTCAATCGCCGGCCGGGCTTGGA	GATGGCTGGCCTTGTCCCCTCCCTGCCGACTCCGACGGTGGCGGTCACGT
ACGGCCTCAAGCGCCGGCCGGGCTGGGG	TTTGGTGTGGTTGGGCTCCGCCCCTCCGTGCCCGCCGTGACCCTGGGGGTCACCGA
CTGGCCTCAAGCGCCGGCCGGGCTGGAA

>NZ_CP014485|25|7|4068070-4068296|PILER-CR
CTGTCCGGGATGGCCTCAATCGCCGGCCGGGCTTGGAGATGGCTGGCCTTGTC	CCCTCCCTGCCGACTCCGACGGTGG
CGGTCACGTACGGCCTCAAGCGCCGGCCGGGCTGGGGTTTGGTGTGGTTGGGC	TCCGCCCCTCCGTGCCCGCCGTGACCCTGGGGGTCACCGACTGGCCTCAAGCGCCGGCCGGGCTGGAAAAGATGGCCTC
AATCGCCGGCCAGGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_079076014.1|4069019_4070240_+|zinc-dependent-metalloprotease	unknown	unknown	gnl|CDD|274833
NZ_CP014485.1|WP_003948936.1|4078748_4079915_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213262
NZ_CP014485.1|WP_015507654.1|4062962_4063664_+|VTT-domain-containing-protein	unknown	unknown	gnl|CDD|182775
NZ_CP014485.1|WP_003948938.1|4077270_4077741_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|379209
NZ_CP014485.1|WP_003948951.1|4062108_4062867_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|377906
NZ_CP014485.1|WP_061404699.1|4066259_4067789_+|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	unknown	unknown	gnl|CDD|334815
NZ_CP014485.1|WP_008411390.1|4063745_4065395_-|threonine/serine-exporter-family-protein	unknown	unknown	gnl|CDD|377697
NZ_CP014485.1|WP_061404695.1|4057967_4059473_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143469
NZ_CP014485.1|WP_008406593.1|4077812_4078673_-|dihydropteroate-synthase	unknown	unknown	gnl|CDD|238380
NZ_CP014485.1|WP_010645123.1|4056976_4057840_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP014485.1|WP_061404698.1|4061028_4061655_-|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl|CDD|179647
NZ_CP014485.1|WP_003948942.1|4074747_4075353_+|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl|CDD|236472
NZ_CP014485.1|WP_061404697.1|4060344_4061007_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP014485.1|WP_018469980.1|4072558_4074601_+|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl|CDD|273520
NZ_CP014485.1|WP_003948940.1|4076068_4076668_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl|CDD|223872
NZ_CP014485.1|WP_003948948.1|4065634_4066123_-|inorganic-diphosphatase	unknown	unknown	gnl|CDD|376376
NZ_CP014485.1|WP_008406585.1|4071749_4072289_+|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|223707
NZ_CP014485.1|WP_003948941.1|4075436_4075925_-|DUF3180-domain-containing-protein	unknown	unknown	gnl|CDD|378650
NZ_CP014485.1|WP_075986980.1|4076664_4077033_-|dihydroneopterin-aldolase	unknown	unknown	gnl|CDD|376737
NZ_CP014485.1|WP_061404696.1|4059660_4060227_+|DinB-family-protein	unknown	unknown	gnl|CDD|368218

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_079076014.1|4069019_4070240_+|zinc-dependent-metalloprotease	gnl|CDD|274833	TIGR03883, DUF2342_F420, uncharacterized protein, coenzyme F420 biosynthesis associated. A phylogenetic tree of the DUF2342 family (TIGR03624) consists of two major branches. One of these branches, modeled here, is observed almost entirely to be found in coenzyme F420 biosynthesizing species of the Actinobacterial, Chloroflexi and Archaeal lineages. The few organisms having genes within this family and lacking F420 biosynthesis may either have an undiscovered F420 transporter, or may represent F420-to-FMN revertants. This family includes a Chloroflexus Aurantiacus protein whose crystal structure has been determined (PDB:3CMN_A). This has been annotated as a putative hydrolase, but the support for that assertion is untraceable. There is no cofactor present in the structure.	3.93216e-159
NZ_CP014485.1|WP_003948936.1|4078748_4079915_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl|CDD|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.98188e-149
NZ_CP014485.1|WP_015507654.1|4062962_4063664_+|VTT-domain-containing-protein	gnl|CDD|182775	PRK10847, PRK10847, DedA family protein.	1.47727e-52
NZ_CP014485.1|WP_003948938.1|4077270_4077741_-|nuclear-transport-factor-2-family-protein	gnl|CDD|379209	pfam13474, SnoaL_3, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.34894e-26
NZ_CP014485.1|WP_003948951.1|4062108_4062867_+|MerR-family-transcriptional-regulator	gnl|CDD|377906	pfam07739, TipAS, TipAS antibiotic-recognition domain. This domain is found at the C-terminus of some MerR family transcription factors. The domain has an alpha-helical globin-like fold. The family includes Mta a central regulator of multidrug resistance in Bacillus subtilis.	3.57422e-46
NZ_CP014485.1|WP_061404699.1|4066259_4067789_+|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	gnl|CDD|334815	pfam02113, Peptidase_S13, D-Ala-D-Ala carboxypeptidase 3 (S13) family.	7.10335e-59
NZ_CP014485.1|WP_008411390.1|4063745_4065395_-|threonine/serine-exporter-family-protein	gnl|CDD|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	4.52957e-59
NZ_CP014485.1|WP_061404695.1|4057967_4059473_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143469	cd07151, ALDH_HBenzADH, NADP+-dependent p-hydroxybenzaldehyde dehydrogenase-like. NADP+-dependent, p-hydroxybenzaldehyde dehydrogenase (PchA, HBenzADH) which catalyzes oxidation of p-hydroxybenzaldehyde to p-hydroxybenzoic acid and other related sequences are included in this CD.	0
NZ_CP014485.1|WP_008406593.1|4077812_4078673_-|dihydropteroate-synthase	gnl|CDD|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	1.96156e-110
NZ_CP014485.1|WP_010645123.1|4056976_4057840_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.10877e-08
NZ_CP014485.1|WP_061404698.1|4061028_4061655_-|NAD(P)H:quinone-oxidoreductase	gnl|CDD|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	5.50926e-45
NZ_CP014485.1|WP_003948942.1|4074747_4075353_+|GTP-cyclohydrolase-I-FolE	gnl|CDD|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	1.11788e-115
NZ_CP014485.1|WP_061404697.1|4060344_4061007_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.62556e-08
NZ_CP014485.1|WP_018469980.1|4072558_4074601_+|ATP-dependent-zinc-metalloprotease-FtsH	gnl|CDD|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP014485.1|WP_003948940.1|4076068_4076668_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl|CDD|223872	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism].	2.11636e-64
NZ_CP014485.1|WP_003948948.1|4065634_4066123_-|inorganic-diphosphatase	gnl|CDD|376376	pfam00719, Pyrophosphatase, Inorganic pyrophosphatase.	1.73356e-85
NZ_CP014485.1|WP_008406585.1|4071749_4072289_+|hypoxanthine-phosphoribosyltransferase	gnl|CDD|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	1.73523e-91
NZ_CP014485.1|WP_003948941.1|4075436_4075925_-|DUF3180-domain-containing-protein	gnl|CDD|378650	pfam11377, DUF3180, Protein of unknown function (DUF3180). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	1.3504e-27
NZ_CP014485.1|WP_075986980.1|4076664_4077033_-|dihydroneopterin-aldolase	gnl|CDD|376737	pfam02152, FolB, Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate.	8.67586e-45
NZ_CP014485.1|WP_061404696.1|4059660_4060227_+|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	1.59267e-38

Protein sequences

>NZ_CP014485.1|WP_061404699.1|4066259_4067789_+|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase
MSGRGGWRLKTWQFTAAAAVSGLALASAAAAAAGPWDSGGQRTAESRRAALLPGTGDGDHRTEAGSPLPAGSDPVASEAAAVLAPLEAGNLAPRTGEGAREAAAGQAPVPTAAALEFALEPLLKAKGLGPGATASVVDAATGKELYGRGAKTAMVPASTVKIATGTAALSVLGPDHRIRTTVVAEPGPGYEDGAPPERIVLVGGGDPTLTARADAAGNASLRTLARHAADTLKQRGARTVRLAYDTSAYSGSTRHPIGPNENLAPVTALMADEGRLDTSTSGPAPRSTRPAQDAADAFARFLAERGVKVEGAVREAAATDQAEKLADVRSAPLSALVERMLTHSDNDIAEALARQTALAAGAKADFAGAERETRRALGRLGLPLDGARFADGSGLDRADRVTARLLTSLLARAAHTDHPELRPVLTGLPVAGFSGTLAGRYTDSEAAAGTGVVRAKTGTLTGVNTLAGTVVSTDGRLLTFSFLASATTDPTTAQSTLDHLASTLAHCGC
>NZ_CP014485.1|WP_003948948.1|4065634_4066123_-|inorganic-diphosphatase
MEFDVTIEIPKGSRNKYEVDHETGRIRLDRRLFTSTSYPADYGFVEDTLGEDGDPLDALVLLDDPTFPGCLISCRVIGMFRMTDEAGGDDKLLCVPAGDPRVDHLKDIQDVSEFDRLEIQHFFEVYKDLEPGKSVEGADWVGRAEAEAEIERSYQRAKEAGH
>NZ_CP014485.1|WP_008411390.1|4063745_4065395_-|threonine/serine-exporter-family-protein
MTEDADDRKPQSDEARSAFTPPQGVPQSQAPENESQITSEFALPEGLAAPPAGEDAERSAFTPPATYDARSAPPAFTPAQGIPMVRLAKNSPWQDRMRAMIRLPVAERPAPDLTQKTDDSGPAVPRVLDLTLRIGELLLAGGEGAEDVEAAMFAVSRSYGLDRCEPNVTFTLLSISYQPSLVDDPLTASRTVRRRGTDYTRLAAVYRLVDDISSDDTEVSLEEAYRRLAEIRRNRHPFDTWALTLAAGLLAGGASMLVGGGLVVFVAAALGAIAGDRMAWVFAGRGLPEFYQFAVAAMPPAAIGIALQLAHVEVRASAVITGGLFALLPGRALVAGVQDGLTGYYITAAARLLEVMYLFIGIVVGVLVMLYVGVQLGAELQPREALLSVERPPIQIIAAMALTLAFAVLLQQERSTVLLVTLNGGVAWSVYGAMHFAGNISPVASTAVAAGLVGLFGQLLSRIQFASALPYVTAAIGPLLPGSATYYGLLGIVQGDVNTGLSSLSTAIALALAIAIGVNLGGETARLFLRVPGGPDAATRRAAKRTRGF
>NZ_CP014485.1|WP_015507654.1|4062962_4063664_+|VTT-domain-containing-protein
MNTLALGPSWLDPDYLLNQFGIYGLLLIVFAESGLLIGFFLPGDSLLFTTGLLITTSQLKFPLWLAIVLICVAAVVGDQAGYLFGKKVGPALFKRPDSRLFKQENVTKASEFFDKHGPKSLVLARFVPIVRTFTPIIAGVSSMRYRSFITFNILGGILWGAGVTLLGAWLGQIAFVRENIEAMLILIVLVSVVPIIIEFVKARGQSKRAAAAGPGAGPTPPPAPPQRGRHAKR
>NZ_CP014485.1|WP_003948951.1|4062108_4062867_+|MerR-family-transcriptional-regulator
MEYTVGQVAAVAGVTVRTLHHYDAIGLLSPSGRSAAGHRRYGDGDLDRLQRILFHRALGFALDEIAALLDDPDADPRAHLRRQHALLTDRIETLRRMADAVAAAMEAAQMGINLTPEEKFEVFEGYDPDQYADEARQRWGHTDAYRESQRRTASYTKADWQRLKDEFDALHARVAELLAQGVPADAPEAMDAAEEHRRFIDGAHYPCDARMHTCLADMYVADPRFTATYEAIRPGLAQYLHDAIHANARRTE
>NZ_CP014485.1|WP_061404698.1|4061028_4061655_-|NAD(P)H:quinone-oxidoreductase
MPGTVNVAVIYYSSTGTIARIADAMATAATEAGAHVRLRKVRELAPQAAIDSNPAWAANADATKDLPEAEPDDMVWADAVIFGSPTRYGNVSAQLKQFIDTLGGLWAEGRLADKVYSGFTASSTAHGGQESTLLALYNTVHHFGGILVAPGYTDPSKFVDGNPYGTSHVSGQGDLPVGDQTFQATKVQAERVVRVARALKEGGLTGGA
>NZ_CP014485.1|WP_061404697.1|4060344_4061007_+|PadR-family-transcriptional-regulator
MSAIRMLVLGAVRQHGRAHGYQVRNDLEFWGAHEWSNAKPGSIYHALKQLARQGLLVAHETAPSTAGGPPRTEYSVTGEGEEEFFRLLRAALTGYDQKPDLLYAALGFLVDLERAEAVTLLQERLRSIQEWRRSVTEYWTPEAGPESIGHIGEIMNLWVHSADTGAEWTRGLIARIEAGAYTFAGEGEPFRGILTGGEPNPYATEGNPYREGAPPAARPE
>NZ_CP014485.1|WP_061404696.1|4059660_4060227_+|DinB-family-protein
MVVHVDPEARGDERGALLAFLDAERGGIRRALLGLSDQAAATRPSASELSLSGLLKHVRLTEQSWLERATGTAPEPAEGETYADQEHGYELVGEETVASELAAWEAVARRTEEFIHAAETLDATFALPDAPWFPPGQRVSLRWLLLRLITETARHAGHADIIRESLDGAVAFELVAKERGEERGEEWG
>NZ_CP014485.1|WP_061404695.1|4057967_4059473_+|aldehyde-dehydrogenase-family-protein
MSDSTVPAGAAASGPGFADFGRLAHQYIDGRWRTGTGSWDIIDFNPFNGEKLAAITVATVSEVDEAYRAAERAQKPWAAAGPHARRTVLEKALRITEEHTAQIVEAMCEEQGATRSKARHEVEMACEFLREAIRLTVRPEGVILPASQRSRENRVYRLPVGVVGVISPFNFPFLVALKTVAPALALGNAVVVKPNQNTPVVGGGLIARIFEEAGLPAGLLNVVVTDIAEIGDALIAHPVPRVISFSGSDRVGRHVGAVAASHLKRTVLELSGNSALVVLADADVDYAVDAAVFSRFVYQGQVCMAANRILVDRSVEAEFTEKFTARVRALRTGDPREEETDLGPVISDFQADALSAMVDRALAEGATALVHGRTLGNLVEPTVLAGVPADSALLHQEIFGPVVVLVPFDGDDEAVRIANDTPYGLSGAVHTADAERGVNFAHRVETGMIHVNDSTVQDDPQVAFGGEKASGSGRLNGEATVEAFTTQKWISVQHGRSIFPF
>NZ_CP014485.1|WP_010645123.1|4056976_4057840_+|helix-turn-helix-domain-containing-protein
MTAGESGGSVVRRILLGSQLRRLREGRGITREAAGYSIRASESKISRMELGRVSFKARDVEDLLTLYGVADGAERAALLDLAREANVAGWWHSYSDVLPGWFQTYVGLEGAASLIRVYEVQFVHGLLQTEAYAHAVVERGMPGASAAEIDRRVALRLERQKLLVSERAPGFHVVLDEAALRRPYGDRTVMREQLEHLIEISERPNVTLQVMPFSFGGHAGESGAFALLRFPESDLSDVVYLEQLTSALYLDKREEVAQYERAMERLQRDSPDPSRTRDLLRGLVQLT
>NZ_CP014485.1|WP_079076014.1|4069019_4070240_+|zinc-dependent-metalloprotease
MTSIGGVEMVDWKLAVTTASRLARPGPEITREEAREVVAELRGHAVAAEEHVRAFTGMTTAAGHDTPVLVVDRPGWIEANVAGFRSLLKPLMTKMRARRGNGPGGMIAGAVGGKVTGVELGVLLSFLSSRVLGQYETFAPATRELPGAPDGGGRLLLVAPNIVHVERELGVDPHDFRLWVCLHEETHRTQFTAVPWLRDHLEAEIQAFLAETDVDAGTLLERLSDAVQAFTGGRRGESAEPSATGTATDTATATAPETEPGARSGAHAPEQDIDGRSLVDLVQTPVQREILARVTAVMSLLEGHADYVMDGVGPQIVPSVVEIREKFQRRRAVGANRLDQILRRLLGLDAKLRQYRDGERFVRAVVEEVGMEGFNRVWTSPNTLPTPAEITHPAEWIARVHRGPEA
>NZ_CP014485.1|WP_008406585.1|4071749_4072289_+|hypoxanthine-phosphoribosyltransferase
MGSDLQSVLLTKEEIDAKLVELAEQIDQEYAGKDLLIVGVLKGAVMVMADLARTLSTPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIQGKHVLIVEDIIDSGLTLSWLISNLGSRGPASLKVCTLLRKPEAAKVAIDVEWVGFDIPNEFVVGYGLDFAEKYRNLPFVGTLAPHVYGG
>NZ_CP014485.1|WP_018469980.1|4072558_4074601_+|ATP-dependent-zinc-metalloprotease-FtsH
MDVKRYFRGPVMWIVLAVLAVVVLMQVVGSSGGHKTVDTGQVVQAINDKQVQSASLTTGDDQMIKVDLKDGQKIDGSTKIQASYIGDMGFDLARKLQAGYEDKSIPEGYTVSPSKQSPFLSILLSLLPFVLIVLVFLFLMNQMQGGGSRVMQFGKSKAKLITKDTPKTTFADVAGSDEAVEELHEIKEFLQEPAKFQAVGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFEQAKANAPAIVFVDEIDAVGRHRGAGMGGGHDEREQTLNQLLVEMDGFDVQGGVILIAATNRPDILDPALLRPGRFDRQIAVDRPDMQGRLEILKVHVKGKPVAPDVDLSAVARRTPGFTGADLANVLNEAALLTARSDQKLIDNHMLDEAIDRVVAGPQKRTRIMSDKEKKITAYHEGGHALVAAASPNSDPVHKITILSRGRALGYTMVLPEEDKYSTTRNEMLDQLAYMLGGRAAEELVFHDPTTGAANDIEKATGTARAMVTQYGMTERLGAIKFGGDNTEPFLGRDMAHQRDYSEEVAALVDEEVKKLIETAHNEAWEILVENRDVLDNLVLQLLEKETLGKEEIAEIFATIVKRPARPAWTGSTRRTPSTRPPVLSPKELSLTNGANGSPAALGTGPANGSTPDLTKPPASPEDRPEE
>NZ_CP014485.1|WP_003948942.1|4074747_4075353_+|GTP-cyclohydrolase-I-FolE
MTDPVTLDGLGAIGEFDEKRAEHAVRELLLAVGEDPDREGLRETPARVARAYREIFAGLWQKPEDVLTTTFDLGHDEMVLVKDIEVQSSCEHHLVPFVGVAHVGYIPSADGKITGLSKLARLVDVYARRPQVQERLTTQIADSLMEILEPRGVIVVVECEHMCMTMRGVRKPGAKTITSAVRGQLRDAATRNEAMSLIMAR
>NZ_CP014485.1|WP_003948941.1|4075436_4075925_-|DUF3180-domain-containing-protein
MKQLRIRTLAGLLVVAAVLSWAGARLWDAFGTLPAVPLFAPIVLAAIAAVLLATALAFRSRLRAQRERRPEAKGVDPLVAARALVFGQASALVAALVAGMYGGVTVFLLGYLEVPARADQALYAGTSLVAGAGVIAAGLYLERVCKLPEDGDDNTPGAAPTV
>NZ_CP014485.1|WP_003948940.1|4076068_4076668_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MNPNSSDPTVQPVPASVVEQVDAADVTLSNPKTAVISLGSNLGNRLETLQGAVDALEDTPGLRVKAVSPVYETEPWGVDPGSQPSYFNAVAVIRTTLPPGSLLERAQAVEEAFHRVRDERWGPRTLDVDIVAYAGVVSADPELTLPHPHAHERAFVLAPWHDVDPEAELPGQGPVDELLSALAGDGLTRREDLELRLPE
>NZ_CP014485.1|WP_075986980.1|4076664_4077033_-|dihydroneopterin-aldolase
MIRVDRVALRGLKGRGHHGVFPKEREEGQTFIVDLVLGLDTRPAAESDDLTRTVHYGVVAEEVVAVVEGEPVNLIETLAERIARTCLKTDAVQEVEVTVHKPDAPITVPFDDVTVTITRSRV
>NZ_CP014485.1|WP_003948938.1|4077270_4077741_-|nuclear-transport-factor-2-family-protein
MTPTEIEQVERANAEYYDIVERGDYAELAALWLDEESLSCVHPGWPVLSGRGEVLRSYAVIMANTDYIQFILTDVQTSLLGATAIVTCTENILSGGPPPEDGELGPLVGQLVVATNVFRRTTEGWKLWSHHASPVLAELEAEEGDGDGGPGEESPA
>NZ_CP014485.1|WP_008406593.1|4077812_4078673_-|dihydropteroate-synthase
MSTSFGRGRVAGLPEWDRCAVMGVVNVTPDSFSDGGRWFDTERAVKHGLDLASRGADLIDVGGESTRPGAPRVDEAEELRRVVPVVRALAAEGLVVSVDTMRAAVAEQSLAAGALLVNDVSGGLADPAMIPAVAAAGAPFVVMHWRGFSDAMNSRAVYADVVGEVTDELRTRIDAAVDGGIAPDRIVVDPGLGFAKEAPHDLALVAHLDRLRALGHPLLVAASRKRFLGRVLAGPDAAPPPARERDAATAAISALSAQAGAWAVRVHDVRPTADAVRVARAVEAAR
>NZ_CP014485.1|WP_003948936.1|4078748_4079915_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MIRFEQVSKVYADGTTAVDDLTFEVAAGELVTLVGPSGCGKTTTMKMVNRLIEPTSGRISLDGEDISAVDPVELRRRIGYVIQQVGLFPHKTVLENTATVPHLLGWKRAKARARAAELLELVGLDPSTHGARYPEQLSGGQRQRVGVARALAADPPVLLMDEPFGAVDPVVREHLQNEFLKLQAEVHKTVLFVTHDIEEAVRLGDRIAVYGHGRIEQFDTPAAVLGAPATPYVADFVGADRGLKRLSVTPIEPGDLVRPPVVHLDDPLAAAGERLRAEGARWAVVLDGEEKLHGWISSARTEGAEGTVGEQARRMEAWLPVGAPLKRAFATMLQHDAGWIAVLDPDADHRFLGVLTPAALHEALRRSTAADSRAVPRQEVALETVHAV

Crispr_ID: NZ_CP014485_26

• CRISPR_ID: NZ_CP014485_26
• CRISPR_location: 4513592-4513677
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_26

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCTG	CRISPRCasFinder

spacers of NZ_CP014485_26

>26.1|4513616|38|NZ_CP014485|CRISPRCasFinder
GTTTTGGTGCGGACACGTCTGACCGTGCCGGTCACCGA

CRISPR arrays and Neighbor proteins around NZ_CP014485_26

CRISPR arrays

The CRISPR arrays of NZ_CP014485_26

>merge|NZ_CP014485|26|4513592-4513677|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGGTTTTGGTGCGGACACGTCTGACCGTGCCGGTCACCGATGGCCTCAAGCGCCGGCCGGGCTG

>NZ_CP014485|26|20|4513592-4513677|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTG	GTTTTGGTGCGGACACGTCTGACCGTGCCGGTCACCGA
TGGCCTCAAGCGCCGGCCGGGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003948567.1|4519823_4520399_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|236607
NZ_CP014485.1|WP_010638764.1|4505231_4505894_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl|CDD|274750
NZ_CP014485.1|WP_003948570.1|4517094_4517991_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NZ_CP014485.1|WP_003948565.1|4522171_4523299_+|GuaB3-family-IMP-dehydrogenase-related-protein	unknown	unknown	gnl|CDD|236322
NZ_CP014485.1|WP_061404758.1|4509110_4510481_-|MFS-transporter	unknown	unknown	gnl|CDD|340883
NZ_CP014485.1|WP_003948581.1|4506452_4507589_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl|CDD|236585
NZ_CP014485.1|WP_003948582.1|4505890_4506460_+|ribosomal-protein-S18-alanine-N-acetyltransferase	unknown	unknown	gnl|CDD|273701
NZ_CP014485.1|WP_003948573.1|4513962_4514271_+|co-chaperone-GroES	unknown	unknown	gnl|CDD|178988
NZ_CP014485.1|WP_003948566.1|4520560_4522069_+|IMP-dehydrogenase	unknown	unknown	gnl|CDD|376340
NZ_CP014485.1|WP_008414818.1|4507585_4507861_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_037843101.1|4518169_4518514_-|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP014485.1|WP_030304951.1|4510477_4511128_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|378968
NZ_CP014485.1|WP_061404757.1|4508074_4508491_+|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341390
NZ_CP014485.1|WP_003948578.1|4508600_4509080_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003948572.1|4514428_4516051_+|chaperonin-GroEL	unknown	unknown	gnl|CDD|234573
NZ_CP014485.1|WP_003948568.1|4518959_4519571_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP014485.1|WP_003948564.1|4523390_4524656_-|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl|CDD|223749
NZ_CP014485.1|WP_008413971.1|4516142_4516955_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|223377
NZ_CP014485.1|WP_008414824.1|4512544_4513483_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|366688
NZ_CP014485.1|WP_059212579.1|4511233_4512442_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|380115

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003948567.1|4519823_4520399_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|236607	PRK09648, PRK09648, RNA polymerase sigma factor ShbA.	2.14712e-89
NZ_CP014485.1|WP_010638764.1|4505231_4505894_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl|CDD|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	2.18837e-64
NZ_CP014485.1|WP_003948570.1|4517094_4517991_+|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.41333e-56
NZ_CP014485.1|WP_003948565.1|4522171_4523299_+|GuaB3-family-IMP-dehydrogenase-related-protein	gnl|CDD|236322	PRK08649, PRK08649, GuaB3 family IMP dehydrogenase-related protein.	0
NZ_CP014485.1|WP_061404758.1|4509110_4510481_-|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.31815e-13
NZ_CP014485.1|WP_003948581.1|4506452_4507589_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl|CDD|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	6.79181e-179
NZ_CP014485.1|WP_003948582.1|4505890_4506460_+|ribosomal-protein-S18-alanine-N-acetyltransferase	gnl|CDD|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	2.19163e-31
NZ_CP014485.1|WP_003948573.1|4513962_4514271_+|co-chaperone-GroES	gnl|CDD|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	3.64761e-49
NZ_CP014485.1|WP_003948566.1|4520560_4522069_+|IMP-dehydrogenase	gnl|CDD|376340	pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain. This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains pfam00571 are inserted in the TIM barrel. This family is a member of the common phosphate binding site TIM barrel family.	0
NZ_CP014485.1|WP_037843101.1|4518169_4518514_-|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.05727e-27
NZ_CP014485.1|WP_030304951.1|4510477_4511128_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	4.46532e-10
NZ_CP014485.1|WP_061404757.1|4508074_4508491_+|CBS-domain-containing-protein	gnl|CDD|341390	cd04622, CBS_pair_HRP1_like, CBS pair domain found in Hypoxic Response Protein 1 (HRP1) -like proteinds. Mycobacterium tuberculosis adapts to cellular stresses by upregulation of the dormancy survival regulon. Hypoxic response protein 1 (HRP1) is encoded by one of the most strongly upregulated genes in the dormancy survival regulon. HRP1 is a 'CBS-domain-only protein; however unlike other CBS containing proteins it does not appear to bind AMP. The biological function of the protein remains unclear, but is thought to contribute to the modulation of the host immune response. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	7.75019e-36
NZ_CP014485.1|WP_003948572.1|4514428_4516051_+|chaperonin-GroEL	gnl|CDD|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP014485.1|WP_003948568.1|4518959_4519571_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.73082e-50
NZ_CP014485.1|WP_003948564.1|4523390_4524656_-|nucleotide-sugar-dehydrogenase	gnl|CDD|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	1.59681e-121
NZ_CP014485.1|WP_008413971.1|4516142_4516955_-|SDR-family-oxidoreductase	gnl|CDD|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	4.28598e-81
NZ_CP014485.1|WP_008414824.1|4512544_4513483_+|polysaccharide-deacetylase-family-protein	gnl|CDD|366688	pfam01522, Polysacc_deac_1, Polysaccharide deacetylase. This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It also includes chitin deacetylase from yeast, and endoxylanases which hydrolyzes glucosidic bonds in xylan.	6.13693e-35
NZ_CP014485.1|WP_059212579.1|4511233_4512442_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|380115	pfam18096, Thump_like, THUMP domain-like. This is a domain of unknown function found in bacteria.	1.45483e-18

Protein sequences

>NZ_CP014485.1|WP_008414824.1|4512544_4513483_+|polysaccharide-deacetylase-family-protein
MGQVRQNEQSGGRRLHPGGLLRRTRAARLVAAGLTAAALLSGCALGTESGSGGPGTTGQAGPAPETKAQRLAKKQAAIAAATRRWGLAQVPLTAPAPPDAKPTLSTRDGFEVEGQENLPHVFTTVPVKERVVFLTIDDGAEKDPEFLRMMKELDIPYSAFLSDYLVSEDYDYFRTMQKQGTALHNHTLDHPYLPGLSYEEQRHQICGMQDIIEKQYGKRPRLFRPPYGNYNQDTLKAAKSCGIEAVPLWNAEAFIDRVDYREWDRDLHPGDIVLTHFRGTGQWDGTMVDMVRQAMKVITSKGYAVARLEDYI
>NZ_CP014485.1|WP_059212579.1|4511233_4512442_-|class-I-SAM-dependent-methyltransferase
MTDLDSFTALLTPEGRALLDAVAGHDPADELATATRLRRDHPAPLVSAALGQARLRQRAAVKFGADAARMFFTPHGVEQATRTEVAAHRAARIAALGVRSVADLCCGIGGDAVALARAGVRVLAVDRDPVTAAVARANAEALGLAELIEVREAEVAEVEVGGYDAVFVDPARRGGRGGRVFDPEAYSPPLSWAVEAALRAPVAALKIAPGVPHEAIPPQAEAEWISYGGDVKEAVLWFGGAGAPGGVRPAPGSVRATLLPAGDQLWSPEPPPDVPAGPVGRYLYEPDGAVIRAHQVAEVAERVGGHLVDETIAYVTSDSLRPTPFAAAYEITDVLPFNLKRLKALLREREVGVLTVKKRGSAVEPEEVRRRMKLRGPNAATVFLTRVAGAPTMLVGGPAPAA
>NZ_CP014485.1|WP_030304951.1|4510477_4511128_-|helix-turn-helix-transcriptional-regulator
MPEQPSSRIDLTHNPAALKALTHPLRVRLLGLLRSEGPATASELAATTGETSASTSYHLRVLARHGFVSEAPARDARERRWQAAHTLTTWDNEALLDQPGAEVFLATTRRQQVDHLGRTLDRHEADLAAGRLDPAWRAAAHLDDYEVRLTPASAAELGREFTARAAELAARDDAGNPEAARVVVVTAALPVADRPARDAEAPEAPDAGPAQDGETP
>NZ_CP014485.1|WP_061404758.1|4509110_4510481_-|MFS-transporter
MTAAPAPADAHILDPETARRRYVTVSALFWFPIGLYVPSLVLILGERGLALAAVAAVLSSQGLTVALLELPTGGLSDVLGRRAVLAAGGVLSFAGLLLLALGTVPWVLITGIVLMGASRALASGPAEAWYVDMAQAHSGPEAELRTGLSRGSSAMGASLAVATLLGGLLPWLFAGSGLAAATGGLVLPLSLPGLLSAALVLCYLAYVLLRLPEPPRAPSTLRSVLGSVPGTIASGVRLATRERVVRKVVLTTAAVGAALGAIELLTPGRAAAITGASESGAVVYAGLATAGFASSSLGARLAPLLARLTGGSGRAVLTALGGMACGLALLGVSAPGAGESASTPAVVTGVLGYVLVYLCLGAAGPNENDLLHHRVASSARATALSVQSLALQAVASLGGLVAGLLPLGPLPLLLTAAVVGAGALMWVRAVPDGPRPGHPDGADALAAPAASGEPGR
>NZ_CP014485.1|WP_003948578.1|4508600_4509080_-|hypothetical-protein
MSDSEDFDAFGDDVYQPQGEDTTDDSGIFDEEDNLMNTGLDDLRDEGYSPPEKPRAVEHTGTTAEEEREGESLDERLTEEVPDVQVPPGDGLGDTLDTDGELIDDEVGDLRAGRLVAPDEGAHEDAEKDIIAEDVGIDGAAASAEEAAVHLVDEDADDL
>NZ_CP014485.1|WP_061404757.1|4508074_4508491_+|CBS-domain-containing-protein
MADARTLMSTDVQSILAEETIDRAAQVMRDHNVGALPVKSADGALLGIVTDRDLVVRALAAGKTPDRTTLEDLVEDTPVAVTPDAHSAEVLQAMGNAQVRRVVVVEDGDLLGIISEADLAQHLADEDLAAFVRRVYQG
>NZ_CP014485.1|WP_008414818.1|4507585_4507861_+|hypothetical-protein
MTAHTLMWEARATQGRGADLLEWTRTRAAELAEATPSPLRTELFQAPQDRVLCLTWWHPDHGPDLPELPEPPAELITRAVHRWHFESVEVL
>NZ_CP014485.1|WP_003948581.1|4506452_4507589_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MADHRDEPLVLGIETSCDETGVGIVHGTTLLADAVASSVDEHARFGGVVPEVASRAHLEAMVATIERALTDAGVKARDLDGIAVTAGPGLAGALLVGVTAAKAYAYALGKPLYGVNHLASHICVDQLEHGRLPEPTMALLVSGGHSSLLLSSDITSDVRPLGATIDDAAGEAFDKIARVLQLGFPGGPVIDRLAREGDPEAIAFPRGLTGPRDAAYDFSFSGLKTAVARWIEAKRAAGEEIPVRDVAASFQEAVVDVLTRKAVRACKDEGVDHLMIGGGVAANSRLRALAEERCERAGIRLRVPRPGLCTDNGAMVAALGAEMVARNRAASDWQLSADSSLPVTETHVPGDAHLHPHPHSHAHSHDHVHETAKDNLYS
>NZ_CP014485.1|WP_003948582.1|4505890_4506460_+|ribosomal-protein-S18-alanine-N-acetyltransferase
MSSQETAPPEQPVLREMRWWDIDPVLALERELFPDDAWSRGMFWSELAHARGPEATHRYVAAYTGDRLVGYAGLATAGGTGDVQTIAVARDQWGSGLGSRLLTDLLEHATAFDCTEVMLEVRVDNTRAQALYARFGFEPIGFRRGYYQPGNVDALVMRLSDPSVNPAAPATPATDDPDSVPAQGTEHHG
>NZ_CP014485.1|WP_010638764.1|4505231_4505894_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MLLLALDTATPAVTVALHDGERVLASDTQVDARRHGELLLPAVDKLLTGAGLALADVTGVVVGVGPGPYTGLRVGLMTADTFGFALGVPVHGVCTLDGLAYASDLGPDAGPFVVATDARRKEVYWGLYADSRTPLSGPAVDRPADLADRVAGLPAVGAGALLYPETFADARAPEHVSAAALASVAAERLAAGEELLPPRPLYLRRPDAQVPKNYKVVTPK
>NZ_CP014485.1|WP_003948573.1|4513962_4514271_+|co-chaperone-GroES
MTTASSKVAIKPLEDRIVVQPLDAEQTTASGLVIPDTAKEKPQEGVVLAVGPGRFENGERLPLDVKTGDVVLYSKYGGTEVKYNGEEYLVLSARDVLAIIEK
>NZ_CP014485.1|WP_003948572.1|4514428_4516051_+|chaperonin-GroEL
MAKILKFDEDARRALERGVNQLADTVKVTIGPKGRNVVIDKKFGAPTITNDGVTIAREVECDDPYENLGAQLVKEVATKTNDIAGDGTTTATVLAQALVREGLRNVAAGASPAALKKGIDAAVAAVSAELLDTARPIDDKSDIAAVAALSAQDKQVGELIAEAMDKVGKDGVITVEESNTFGVDLDFTEGMAFDKGYLSPYMVTDQERMEAVLDDPYILIHQGKIGSIQDLLPLLEKVIQAGGSKPLLIIAEDVEGEALSTLVVNKIRGTFNAVAVKAPGFGDRRKAMLGDMATLTGATVIAEEVGLKLDQAGLDVLGTARRVTVTKDDTTIVDGGGNAEDVQGRVAQIKAEIESTDSDWDREKLQERLAKLAGGVCVIRVGAATEVELKERKHRLEDAISATRAAVEEGIVSGGGSALVHAVKVLDDNLGRTGDEATGVAVVRRAAVEPLRWIAENAGLEGYVITTKVAELDKGQGFNAATGEYGDLVKAGVIDPVKVTRSALENAASIASLLLTTETLVVEKPAEEEPEAGHGHGHSH
>NZ_CP014485.1|WP_008413971.1|4516142_4516955_-|SDR-family-oxidoreductase
MTTALITGSTAGIGAAFARRLAASGTDGSGADRGHGAGHHLVLVARDRERLRRQATELHDRHGVEVEVLPADLSTDEGIGAVEARLADRTHPVDLLVNNAGFGNKGAYLEVPLADELKMLKVHCEAVLRLTTAATASMRERGRGGVVNVASVAAFVPRGTYGASKAWVVQFTQGAAHDLAGSGVRLMALCPGFVRTEFHQRAKMGTDNIPGWMWLDADKLVAAALADLARGRTVSIPDPRYKALMGLVKLTPRALLTGMTSRTGRKYGPQ
>NZ_CP014485.1|WP_003948570.1|4517094_4517991_+|LysR-family-transcriptional-regulator
MIEARHLRVLRAVAATGSFSAAARELGCTQPAVSQQMKALESSAGTPLLIRTGREMRLTQAGEALTRHAAGILAGLTAAEEEVAAIAGLRAGRVRLVSFPSGSSSLVPAALAALRAAHPGTRVSLEEAEPPRSAELLRAGDCDIALAFRYAGATAPDEWDDLVVRPLLADRLVGLVPEGHRLADAASAGIGELAADPWIAGCPRCRRQLVEVCETEGFTPRIDFATDDYPAVLGLVAAGLGVAVLPALALESLRPKGVRTIAVEPAVEREIVALTLPDLAQVPAVAATLDHLAATAGR
>NZ_CP014485.1|WP_037843101.1|4518169_4518514_-|WhiB-family-transcriptional-regulator
MADFSRLPGPNADLWDWQLLAACRGVDSSLFFHPEGERGAARSARETSAKEVCMRCPVRAECAAHALAVREPYGVWGGLTEDEREELMGRARTRLTPAGAASAPGPTPPGPGFP
>NZ_CP014485.1|WP_003948568.1|4518959_4519571_+|response-regulator-transcription-factor
MTSVLVCDDSPLAREALRRAVATVPGVERVTTAANGEEVLRRWGADRSDLILMDVRMPGLGGVETVRRLLSADPGARIIMLTVAEDLDGVALAVAAGARGYLHKDASRAELRATVTQALADPTWRLAPRRLRSAEMGAAPTLTAREIQVLEGMSHGRSNAEIGRELFLSEDTVKTHARRLFKKLGASDRAHAVALGFRWGLVR
>NZ_CP014485.1|WP_003948567.1|4519823_4520399_+|sigma-70-family-RNA-polymerase-sigma-factor
MRDDETTAIGGLVHRAVEGDEQATHDLLAHVHPLALRYCRTRLSRLPGDARHFVEDLAQEVCVAVLLALPRYKDTGRPFEAFVFAIAGHKVADLQRAAMRHPGSTAVPSDEMPERPDDSLGPEERALLSSDAAWAKQLLANLPQNQRELLLLRIAVGLTAEETGQMLGMSPGAVRVAQHRALSRLRALAEQ
>NZ_CP014485.1|WP_003948566.1|4520560_4522069_+|IMP-dehydrogenase
MTANVDGVPEKFATLGLTYDDVLLLPGASDMAPDQIDTTSRLSKNVKVNVPLLSAAMDKVTESRMAIAMARQGGAGVLHRNLSIEDQANQVDLVKRSESGMVTDPITVHPDATLGEADAICAKFRISGVPVTDGSGRLLGIVTNRDMAFESDRTRQVREVMTPMPLVTGKVGISGVDAMELLRRHKIEKLPLVDDEGVLKGLITVKDFVKAEKYPNAAKDSEGRLLVGAAVGVAGDAFERAQALIGAGVDFIVVDTAHGHSRLVGDMVAKIKSNSSGVDVIGGNIATRDGAQMLIDSGADGVKVGVGPGSICTTRVVAGIGVPQVTAIYEASLAAQAAGVPVIGDGGLQYSGDIAKALVAGADTVMLGSLLAGCEESPGELLFINGKQFKSYRGMGSLGAMQTRGDRKSFSKDRYFQEGVASDEKLVPEGIEGQVPYRGPLAQVVHQLVGGLRQSMFYVGGATVPELQRNGRFVRITSAGLKESHPHDIQMTVEAPNYAAKR
>NZ_CP014485.1|WP_003948565.1|4522171_4523299_+|GuaB3-family-IMP-dehydrogenase-related-protein
MTEIEIGRGKRGRRAYAFDDIAVVPSRRTRDPKEVSIAWQIDAYRFELPFLAAPMDSIVSPETAIRVGEFGGLGVLNLEGLWTRYEDPQPLLDEIAEELDEERATRRLQEIYDAPIQEELIGRRIKEVRDAGVITAAALSPQRTAQFSKAVVDAGVDIFVIRGTTVSAEHVSGAAEPLNLKQFIYELDVPVIVGGCATYTAALHLMRTGAAGVLVGFGGGAAHTTRNVLGIQVPMATAVADVAAARRDYLDESGGRYVHVIADGGVGWSGDLPKAIACGADAVMMGSPLARATDAPGKGHHWGMEAVHEDVPRGKLVDLGMVGTTEEILTGPSRTPDGSMNMFGALRRSMATTGYSELKEFQRVEVTVADSHHKR
>NZ_CP014485.1|WP_003948564.1|4523390_4524656_-|nucleotide-sugar-dehydrogenase
MPADLAVIGLGSHGLPLAQAAVGAGVDTIGYDPDRARDLASGRLPGTGAEGALTAADVRRMLSGGFRPTADPRELGRVRTAVICAPAPAGPSGGVDLGPLAEAARALAARLRPHTTVILESPAGPGTTEEFLRPLLESGSGLTAGRDFHLAYSPGRTDPGNRTHGYAATPKVIGGLTPACTESAAAFYGRLTDKVVRARGPREAETVHVLETNYRHVNLALVNEMAVLCHDLGVDLWDVIRCAETKPFGFQAFRPGPGAGGHGLPLDPSCLPHADATPGNGLRMVSLARDINARMPQYVIQRATQLLNEHGKSARAARVLLLGVTYKPDVADQQGAPAQEIALRLTERGASVSYHDPYVPHWSPAGRPVPRADSLYEAAAEADLTILLQNHRTYDLQGLAVKAQLLLDTRGTTPAGAAHRL

Crispr_ID: NZ_CP014485_27

• CRISPR_ID: NZ_CP014485_27
• CRISPR_location: 4648093-4648370
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP014485_27

Consensus_repeat	Method
GGGACCACCCCCGCGTGCGCGGGGACCAC	CRISPRCasFinder
CCACCCCCGCGTGCGCGGGGACCAC	CRT
GGGAGTGGTCCCCGCGCACGCGGGGGTGGTCCC	PILER-CR

spacers of NZ_CP014485_27

>27.1|4648122|32|NZ_CP014485|CRISPRCasFinder
TCGATGATGTTCGTGACGACCGGAGCGGCCTC
>27.2|4648183|32|NZ_CP014485|CRISPRCasFinder
CAGTTGGGGTCGAGGTCGCAGATGTTGACGCC
>27.3|4648244|32|NZ_CP014485|CRISPRCasFinder
CCGTTCGCACCCATGGCGATCACCTGGGACGA
>27.4|4648305|32|NZ_CP014485|CRISPRCasFinder
TCGCCGAGCCACGAGGCCCCCTCCTTCACCTT
>27.5|4648122|36|NZ_CP014485|CRT
TCGATGATGTTCGTGACGACCGGAGCGGCCTCGGGG
>27.6|4648183|36|NZ_CP014485|CRT
CAGTTGGGGTCGAGGTCGCAGATGTTGACGCCGGGA
>27.7|4648244|36|NZ_CP014485|CRT
CCGTTCGCACCCATGGCGATCACCTGGGACGAGGGA
>27.8|4648305|36|NZ_CP014485|CRT
TCGCCGAGCCACGAGGCCCCCTCCTTCACCTTGGGA
>27.9|4648188|31|NZ_CP014485|PILER-CR
AGTTGGGGTCGAGGTCGCAGATGTTGACGCC
>27.10|4648253|31|NZ_CP014485|PILER-CR
CGTTCGCACCCATGGCGATCACCTGGGACGA
>27.11|4648318|27|NZ_CP014485|PILER-CR
GAGCCACGAGGCCCCCTCCTTCACCTT

CRISPR arrays and Neighbor proteins around NZ_CP014485_27

CRISPR arrays

The CRISPR arrays of NZ_CP014485_27

>merge|NZ_CP014485|27|4648093-4648370|CRISPRCasFinder,CRT,PILER-CR
GGGGCTTGCCCCGCCTGCGCGGGGACCACTCGATGATGTTCGTGACGACCGGAGCGGCCTCGGGGCCACCCCCGCGTGCGCGGGGACCACCAGTTGGGGTCGAGGTCGCAGATGTTGACGCCGGGACCACCCCCGCGTGCGCGGGGACCACCCGTTCGCACCCATGGCGATCACCTGGGACGAGGGACCACCCCCGCGTGCGCGGGGACCACTCGCCGAGCCACGAGGCCCCCTCCTTCACCTTGGGACCACCCCCGCGTGCGCGGGGACCACTCTCC

>NZ_CP014485|27|21|4648093-4648365|CRISPRCasFinder
GGGGCTTGCCCCGCCTGCGCGGGGACCAC	TCGATGATGTTCGTGACGACCGGAGCGGCCTC
GGGGCCACCCCCGCGTGCGCGGGGACCAC	CAGTTGGGGTCGAGGTCGCAGATGTTGACGCC
GGGACCACCCCCGCGTGCGCGGGGACCAC	CCGTTCGCACCCATGGCGATCACCTGGGACGA
GGGACCACCCCCGCGTGCGCGGGGACCAC	TCGCCGAGCCACGAGGCCCCCTCCTTCACCTT
GGGACCACCCCCGCGTGCGCGGGGACCAC

>NZ_CP014485|27|3|4648097-4648365|CRT
CTTGCCCCGCCTGCGCGGGGACCAC	TCGATGATGTTCGTGACGACCGGAGCGGCCTCGGGG
CCACCCCCGCGTGCGCGGGGACCAC	CAGTTGGGGTCGAGGTCGCAGATGTTGACGCCGGGA
CCACCCCCGCGTGCGCGGGGACCAC	CCGTTCGCACCCATGGCGATCACCTGGGACGAGGGA
CCACCCCCGCGTGCGCGGGGACCAC	TCGCCGAGCCACGAGGCCCCCTCCTTCACCTTGGGA
CCACCCCCGCGTGCGCGGGGACCAC

>NZ_CP014485|27|8|4648154-4648370|PILER-CR
GGGGCCACCCCCGCGTGCGCGGGGACCACCAGTT	GGGGTCGAGGTCGCAGATGTTGACGCCGGGA
CCACCCCCGCGTGCGCGGGGACCACCCGTTCGCA	CCCATGGCGATCACCTGGGACGAGGGACCAC
CCCCGCGTGCGCGGGGACCACTCGCCGAGCCACG	AGGCCCCCTCCTTCACCTTGGGACCAC
CCCCGCGTGCGCGGGGACCACTCTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061404795.1|4652064_4653285_+|glutathionylspermidine-synthase-family-protein	unknown	unknown	gnl|CDD|367631
NZ_CP014485.1|WP_008410772.1|4638932_4640126_-|family-1-glycosylhydrolase	unknown	unknown	gnl|CDD|274539
NZ_CP014485.1|WP_003948480.1|4641023_4641974_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP014485.1|WP_003948471.1|4651342_4651921_+|hypothetical-protein	unknown	unknown	gnl|CDD|240430
NZ_CP014485.1|WP_003948468.1|4653874_4655128_-|ornithine--oxo-acid-transaminase	unknown	unknown	gnl|CDD|179736
NZ_CP014485.1|WP_003948467.1|4655485_4655983_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_026048057.1|4657339_4658176_-|DUF1206-domain-containing-protein	unknown	unknown	gnl|CDD|377695
NZ_CP014485.1|WP_008410798.1|4656419_4657247_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|379142
NZ_CP014485.1|WP_010638599.1|4641979_4643230_-|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270450
NZ_CP014485.1|WP_008410790.1|4648630_4648843_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008410792.1|4649630_4651058_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NZ_CP014485.1|WP_061404794.1|4648972_4649524_-|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|225039
NZ_CP014485.1|WP_061404793.1|4645906_4646785_-|M55-family-metallopeptidase	unknown	unknown	gnl|CDD|176450
NZ_CP014485.1|WP_037637458.1|4646822_4647932_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP014485.1|WP_008410795.1|4653328_4653862_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP014485.1|WP_162494280.1|4643712_4643850_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404791.1|4643966_4644866_+|acetylxylan-esterase	unknown	unknown	gnl|CDD|225989
NZ_CP014485.1|WP_061404792.1|4645000_4645855_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP014485.1|WP_003948481.1|4640193_4641027_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP014485.1|WP_061404790.1|4637315_4638836_-|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|379232

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_061404795.1|4652064_4653285_+|glutathionylspermidine-synthase-family-protein	gnl|CDD|367631	pfam03738, GSP_synth, Glutathionylspermidine synthase preATP-grasp. This region contains the Glutathionylspermidine synthase enzymatic activity EC:6.3.1.8. This is the C-terminal region in bi-enzymes. Glutathionylspermidine (GSP) synthetases of Trypanosomatidae and Escherichia coli couple hydrolysis of ATP (to ADP and Pi) with formation of an amide bond between spermidine and the glycine carboxylate of glutathione (gamma-Glu-Cys-Gly). In the pathogenic trypanosomatids, this reaction is the penultimate step in the biosynthesis of the antioxidant metabolite, trypanothione (N1,N8-bis-(glutathionyl)spermidine), and is a target for drug design. This region, the pre-ATP grasp region, probably carries the substrate-binding site.	1.1253e-172
NZ_CP014485.1|WP_008410772.1|4638932_4640126_-|family-1-glycosylhydrolase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	5.76e-83
NZ_CP014485.1|WP_003948480.1|4641023_4641974_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.31685e-90
NZ_CP014485.1|WP_003948471.1|4651342_4651921_+|hypothetical-protein	gnl|CDD|240430	PTZ00473, PTZ00473, Plasmodium Vir superfamily; Provisional.	0.00532253
NZ_CP014485.1|WP_003948468.1|4653874_4655128_-|ornithine--oxo-acid-transaminase	gnl|CDD|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_CP014485.1|WP_026048057.1|4657339_4658176_-|DUF1206-domain-containing-protein	gnl|CDD|377695	pfam06724, DUF1206, Domain of Unknown Function (DUF1206). This region consists of two a pair of transmembrane helices and occurs three times in each of the family member proteins.	4.84172e-13
NZ_CP014485.1|WP_008410798.1|4656419_4657247_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	7.11501e-07
NZ_CP014485.1|WP_010638599.1|4641979_4643230_-|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.70213e-130
NZ_CP014485.1|WP_003948481.1|4640193_4641027_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.0156e-89
NZ_CP014485.1|WP_061404794.1|4648972_4649524_-|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	2.35464e-27
NZ_CP014485.1|WP_061404793.1|4645906_4646785_-|M55-family-metallopeptidase	gnl|CDD|176450	cd08663, DAP_dppA_1, Peptidase M55, D-aminopeptidase dipeptide-binding protein family. M55 Peptidase, D-Aminopeptidase dipeptide-binding protein (dppA; DAP dppA; EC 3.4.11.-) domain: Peptide transport systems are found in many bacterial species and generally function to accumulate intact peptides in the cell, where they are hydrolyzed. The dipeptide-binding protein (dppA) of Bacillus subtilis belongs to the dipeptide ABC transport (dpp) operon expressed early during sporulation. It is a binuclear zinc-dependent, D-specific aminopeptidase. The biologically active enzyme is a homodecamer with active sites buried in its channel. These self-compartmentalizing proteases are characterized by a SXDXEG motif. D-Ala-D-Ala and D-Ala-Gly-Gly are the preferred substrates. Bacillus subtilis dppA is thought to function as an adaptation to nutrient deficiency; hydrolysis of its substrate releases D-Ala which can be used subsequently as metabolic fuel. This family also contains a number of uncharacterized putative peptidases.	3.01849e-122
NZ_CP014485.1|WP_037637458.1|4646822_4647932_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.70383e-88
NZ_CP014485.1|WP_008410795.1|4653328_4653862_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	6.09459e-13
NZ_CP014485.1|WP_061404791.1|4643966_4644866_+|acetylxylan-esterase	gnl|CDD|225989	COG3458, COG3458, Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism].	1.075e-53
NZ_CP014485.1|WP_061404792.1|4645000_4645855_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.148e-15
NZ_CP014485.1|WP_008410792.1|4649630_4651058_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.48623e-106
NZ_CP014485.1|WP_061404790.1|4637315_4638836_-|VCBS-repeat-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	4.75492e-05

Protein sequences

>NZ_CP014485.1|WP_037637458.1|4646822_4647932_-|LacI-family-DNA-binding-transcriptional-regulator
MGDGVAGTPTVYDVAGRAGVSIATVSRVYRSPESVREATREKVLVAARELGYVPSGSARGLASRSTGVLGLCFPDYSDPDAESEAATVDADDDHAFMLYSDQIIRGMERAARRHGYALLIAASLTGGPESLVAKVAGRVDGCAVLARTVPTEDLEVISRRLPVVMLAGPPEQDGPGGLDRLDHIEVANAEGQRELTRHLIEDHGLRRLTFVGGIEDSPDAEARFAGFRDACRAAGLPVPDEPDLRAELMTQAGGARAAEELVDRAGPDGLPEGVLFANDQMAVGALHALGRRGLRVPEDLAVTGFDGIPLGRLVQPTLTTVRQPMRRLGEEAVELLVRRLAEEKRGEPESLVLPVEVVRRASCGCGHEA
>NZ_CP014485.1|WP_061404793.1|4645906_4646785_-|M55-family-metallopeptidase
MDNHGSTGEDPTSEAKGPRILISVDMEGVSGIVHPREAHPDGYDYGRARALMTAEANAAVAGVLDAEPGAEVWVADAHGSYRNLLPEEVDRRARLVRGKPRPLGMLGGIDERTDAVLFVGYHVRAGAGPGVLAHTMSDALLDVRVDGRSLGEIGLNAAMAGHLGVPVVLLSGDDAACAEVRELVPGVRTVAVKEALGQFAAAGLHPEEARERLRRTAAEAVAGREEVRPFALSGPQTVEVDLAAAHTVDLAMLIPGVTRAGGARTVTFTAADFGEAYRVVLLLVQLGSIRPA
>NZ_CP014485.1|WP_061404792.1|4645000_4645855_+|alpha/beta-hydrolase
MSGAFSRGSRSPGESRLPVHATVWDDRPNSGGSGSRWPVVLVHGILTWGTDPRYGFAAQRPLAARRRLLLMDRRGYGRSPDIARSDWAVDAEDIVELLGTGAHLVGHAYGGVGALAAAVRRPDLVRSLTLIQPGALRPAARHPVVAEALARARAATAALPPDLTPADFLRGATESVGMETPEATPERLRAAATTMAELPCWDAEIDLGPLARAAFPQLLVSGDWEGAPEPYRTYAGLPLIACAEEIAAATGAAHLVVPGHYPHTQQPERVNAALEHLWEAADQG
>NZ_CP014485.1|WP_061404791.1|4643966_4644866_+|acetylxylan-esterase
MPGGFAGFWRGRYEEALEVVTAPEVGAVEEVRDGVRVCRVSFSSVGGVRLGGWLALPVDGPAEHGFVVGHGYGGRDAPGPDLPLPLPRSAALLPCVRGMGERSRLPGVPSVADAHVLHGISSRDTYVIGACVADLWCAASALLELVPELARHPSGPRLGYLGESFGGGLGALALPWDDRFAAARLTVPTFGNHPLRLTLPCAGSGKSVRRHHRDHPHVVDVLSYFDAATAATFVRVPTLVAAALFDPAVPPPGQFAVHNALADDLRALHVLSAGHFDHPGAEEEAAGLARAEREFFTRL
>NZ_CP014485.1|WP_162494280.1|4643712_4643850_-|hypothetical-protein
MTMGMTATAMTVTGTVTATAMTVTGTVTATATAMTVTVTTTCRRL
>NZ_CP014485.1|WP_010638599.1|4641979_4643230_-|sugar-ABC-transporter-substrate-binding-protein
MHRVARTATAVIAASTALAVVTACGGSSGTEVAADAEQTLTVWAMGAEGEKLAEVAKEYEKENPHLKVKVTPVGWDVAHQKLVSAAAAGNLPDIAQMGGSYLGEFAELGVLEPVDTKRFQEKDFFPAGWQQGEVDGEVYGVPWYVDTRVLYYRTDLAEKAGVDKAPADWKELRALASAYQKDAGTKWGLSIQPSGLDTVQSFYPFLYSAGGEIIDEDGKVVVDSPAAVKALKEYGAYFDKGLANKSVPPGYDVVKDFGNGRVPMFFGGPWHVTLLNEGQPDIKGKWAVAEVPADEASVSMAGGSSLTVSKDSPHKAAAEEFIAHLTSTEGQADWYERTKDLPANTTAWESGSLADDPALKVFEKQMKTAKASPTLANLSEITDKVDQAIAQVTQGKATAEEALGKAKDQIEGLVQK
>NZ_CP014485.1|WP_003948480.1|4641023_4641974_-|sugar-ABC-transporter-permease
MSTTTRKADEAAPGGRRPGRRRGSLGVQNAAGWLFSTPFLVLFAVFMAFPIVATLLMSFTDFGLGNVTRPLDARFIGFENYTRLFGDERFLKSLFNTAYFVVVGVPLTIGLGLLVAVLLNNGIDRARTFFRVGFYAPVVTSIVAVAVVWRFVLDPSDGLIAGLASEVGLTAPDFLGSEALAMPSLIAMAVWRNLGTVMVLFIAGLQAIPTEVREAARLDGVGPWQELRRITIPLLRPTLLYASVITTIGYLNVFEEPFVMTQGGPSDSTLTVSLNMYREGFNFFHMGYASAMAYVLFVVIMGITVLQLRLLKDNTR
>NZ_CP014485.1|WP_003948481.1|4640193_4641027_-|carbohydrate-ABC-transporter-permease
MSAEGRVRRPLTYVLLSGGLLVMAAPFLWMGLSAFKTQRELSASPPVWIPSQWTLANFRQLLADLDLPLYFMNSVIVAVLVTVSNLVFCSMLGYALAKLNFAGRNKVFGVVLGALMVPGNLMLLPLFVLMSKLQLIDSYAGLVLPFAAGAFGVFLMRQFMQSIPDELLEAARMDGAGEWFIFWRIVMPLVKPALATLAILTFLGSWNNFVWPLIATNDPDKYTLPVALATFATDPNKAGGSNGVLMAGSFLIVLPVLAVFIALQRHFTQGIATAGMK
>NZ_CP014485.1|WP_008410772.1|4638932_4640126_-|family-1-glycosylhydrolase
MTSTPFPEGFLWGASTAAHQIEGNNTDSDWWVKEHTAGTHIQEPSYDACDSYHRWPEDMDLLASLGFTDYRFSIEWARIEPVEGHFSRAELAHYRRMVEGAIERGLRPMVTLHHFTVPQWFEARGGWTAEGATELFARYVAACAPVIATGVAHVCTINEPNMIAVMAGQAKRGDIGFPPAGLPTPDEETTHAVIAAHHAAVKEVRAISSGIKVGWTIANQVYQALPGAEEVTAAYRHPREDVFIEAARGDDWIGVQSYTRTRIGADGPIPASPEAERTLTEWEYYPTAVGHALRHTAEVVGDVPLIVTENGIATADDERRTAYYTGALGEVAAAIEDGLKVEGYLAWSALDNYEWGSFRPTFGLIAVDWETFERTARPSAVWLGSLGRTRELPGRAV
>NZ_CP014485.1|WP_061404790.1|4637315_4638836_-|VCBS-repeat-containing-protein
MAWMRRPDTPTTRRGRSGRAAASLAAALLVSGGLSAAALAPTTALAADGPAAASADDFNGDGYADLVSGAPGGTVSGKAGAGYVAVTYGSAKGLAPEPGTVVSRSTAGVPGAATAKQRFGETFAKGDLDGDGYSDLVIGSATAEPGAVILWGSPKGLTGGTAVAGFGQAPQVGDFDGDGQADLALFGAAQVAGDDPVTQEARLFKGPLTREGTPAEQLDFLDRSEWWGYDSDGPACAEDDSCVDGPTSVGGPVRPKAVGDVNGDGSDDLVTWLYEGDGVWAHHLFTGSATGFRDAQEAGPIGSSGDDAAVGIGDVDGDGYDDVVTGSGEATAKVTVRYGSAAGLEGREQAFDQSLPGLHGAQEKGDHFGSCVAVADVTGDGRAEIALGISGEDFSGLTDAGSIALLHGTASGVTGEGSQVLHQNTAGVPGVAESGDKFGSACALLDTDGDGHRDLVAAAAEENEQTGAVWALRGTGEGLTVEGASAFGPGHVGGPVTKAKFGSFLR
>NZ_CP014485.1|WP_008410790.1|4648630_4648843_+|hypothetical-protein
MLTTTRPRTTPVPPPCPDRACHTDIHGRLWKDTTYLRNDPDNWRWYCSRCGQHWMPTHEQFAWYRTLPVA
>NZ_CP014485.1|WP_061404794.1|4648972_4649524_-|carboxymuconolactone-decarboxylase-family-protein
MTTENTPTAPSTSTTPTSPDEKAAAYLPEHTPRISVAELAPDLYRALARADAAARKNLDPVIGELVKIRASQINHCAFCLDMHTKDALAMGESVERIVQLSAWEESKHYYTAKEIAAIELTEAITVLTDGFVPDEVYAQAAAHFDENELAHLIGAITVINAWNRLSVAARNVPGHYVPGSLGQ
>NZ_CP014485.1|WP_008410792.1|4649630_4651058_+|PLP-dependent-aminotransferase-family-protein
MTESWANLGIDLHLEPAGPGLRKGLTDALREAVRSGRLAPGTRLPSSRTLAGDLGIARNTVADAYADLVAEGHLTARQGSGTRVAEQAGPASSVPRRQRPVRVPERAGPAHDLTPGTPDLSAFPRAAWLKAARRALTAAPNDAFGYGDPRGRPELRAALAEYLARVRGVAADPERIVVCAGVAHGLKLVTEVLAARGGHGGRQGAGTVAVETYGLRFHREWLAEEGVGTVPLPFDADGTDPAGLDGERAVLLTPTHQFPMGGTLSPARRAAVVDWARRTGGLILEDDYDGEFRHDRRPVGALQGLAPDRVAYFGTASKALAPGLRLGWLVLPPALVDEVLAAKGYADTCGAPDQLTLAEFLTSGAYDRQVRLMRLRYRRRRDELVATLARRAPSVRVGGIAAGLHAVLLLPPGTESEVLRAAAWHGLGVQGLSWFRHPDAEAAGRPVPEGLVIGYGRPPDHAWQSALETLCRCLP
>NZ_CP014485.1|WP_003948471.1|4651342_4651921_+|hypothetical-protein
MAENITVPAVRALDAPVARPATGPGRGAAPQEPPVADERLPVPVRLTKSGAGEPGSGSGEPSAEQRRKKAARRRVRSSTVALGSMGVLAAALAACGSEPDRRCVDRNSYSYGGGYKVVDSSQCRNGSSGSTGGTGGGGSSGGSGRYGSDRNSNAGWYYGGDSKSGYASDGSFNKSSVSSGGFGCSGKGSGGG
>NZ_CP014485.1|WP_061404795.1|4652064_4653285_+|glutathionylspermidine-synthase-family-protein
MQRHTIEPRPGWQETVEAQGVIYPLTRHPDDSLRPYWDESAYYSFSLAEVEALEEVVEELHAMCLAAAAHIVEKDRFAELGITDPRLASLVTEAWHRKAELPSLYGRFDLWYDGSGAPAKMLEYNADTPTSLVEAASAQWFWMEERFPGADQWNSLHERLVDAWRAQAALLPPGSPVHFAHTIDDECGEDLMTVAYLRETAAQAGLETEAIAVEDIGWDSLSHRFVDQRLRFIRSCFKLYPWEWLATDDFGPHVLDTLDNGGGTGTTLWIEPAWKMLLSNKALLAILWELYPGHPNLLASYLDGPRELAATTGYVTKPLLGREGAGVTLHQPGGTQTPAPATGPSCYQQLALLPDLSTPAHGAHSPTNHVVLGAWVVADEAAGLGIRESAGPVTDGYARFLPHVIL
>NZ_CP014485.1|WP_008410795.1|4653328_4653862_+|GNAT-family-N-acetyltransferase
MPELQRLRADHAPALLAFERENRAWFARTISDRGDAYFADFPARHRALLTYQDEGTDHFHVLVADDATTILGRFNLMDITDGQAELGFRMAESATGRGLATEAARTVCHLAATAYALTSLRAQANLDNLASHTVLTRTGFTATEQTVLRNGTAGRRYVKELAGPEEGAAGAIGAAGL
>NZ_CP014485.1|WP_003948468.1|4653874_4655128_-|ornithine--oxo-acid-transaminase
MSGTPSGTHSSPAPGSATAEAIDAAEAHSAHNYHPLPVVVASAEGAWMTDVDGKRYLDLLAGYSALNFGHANPRLIAAAKAQLDRVTLTSRAFFHDRFAAFCEELAALCGKDMVLPMNTGAEAVETAVKTARKWGYRVKGVPDGAARIVVASGNFHGRTTTIVSFSTDEEARADYGPYTPGFDVVPYGDADALEAALTDDTVAVLLEPIQGEAGVLVPPAGYLRRVRELTAERNVLFIADEIQSGLGRTGRTFACEHEGVVPDLYLLGKALGGGVVPVSAVVGDSDVLGVFRPGEHGSTFGGNPLACAVALEVIAMLRTGEYQARATELGTRLHNALADLVKADGPVRAVRGRGLWAGVDLDPAVGTGREISERLMSRGVLVKDTHGSTIRIAPPLVISAEDLDWGLGELRGVLGMA
>NZ_CP014485.1|WP_003948467.1|4655485_4655983_+|hypothetical-protein
MSALDFCAEVLIEGRIRGAGLGDSMAVWDRCMGYEYTDGLSRGRLRRDYGLVEIIFEQYDTGWHATGIEIQAYRLGRFGVGIVPQVLAPYFGAVESRVNAKELLETVAAKGFGIEAVHEEGARTHAYRVDSSGGVVYVLMAETRSMKVPSVGDVWTVVLELPDEE
>NZ_CP014485.1|WP_008410798.1|4656419_4657247_+|trypsin-like-peptidase-domain-containing-protein
MKKPLAGALLAAALLGASAAPAVAAPGPAAPAAVDLAGTVALSNCSGSVVRAPSASADDPALVLSNGHCLETGFPAPGEVLVDQPSSRSFTLLDGAGNGVGTLRAAKLAYGTMTDTDVSLYQLGESYAEIESAYGIEALELDAARPSEGAAITVASGYWKRTYNCSVDGFAHQLKEGSWTWKDSVRYTDACDTIGGTSGSPVIDDATGKVVAVNNTGNESGGRCTDNNPCEVDENGEVTVREGINYGQQTYTLVPCIGPGSEIDLGREGCAVPKP
>NZ_CP014485.1|WP_026048057.1|4657339_4658176_-|DUF1206-domain-containing-protein
MNSSSMAREGHRQARRAADSKVVSAGARAGFAARGVIYLLVGLLAGQIAFQGDGKQADRGGALQEISGQPFGGILLWVIGIALVGMALWRLSEAAFGAAGPDGDKAMKRVVSGARAVFYAFVAYSVLSFAAGEKSGGGSSDKQSQDITAQALGLPGGQWIVGVAALGVAVAGVVVGARAVMRKYHKHLRMGAMSRRARQFVDVTGVFGGAARGLVFAAAGVFAVMAAVDYDPDEAKGMDDTLRSFADTPAGPWLLVLVAVGLAAFGLFSFANAKWRKV

Crispr_ID: NZ_CP014485_28

• CRISPR_ID: NZ_CP014485_28
• CRISPR_location: 4786987-4787074
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_28

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP014485_28

>28.1|4787010|42|NZ_CP014485|CRISPRCasFinder
GTGGTGGGTAGTTCCGTACGGTTCGAAGGTGCTGGTTCCTGA

CRISPR arrays and Neighbor proteins around NZ_CP014485_28

CRISPR arrays

The CRISPR arrays of NZ_CP014485_28

>merge|NZ_CP014485|28|4786987-4787074|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGTGGTGGGTAGTTCCGTACGGTTCGAAGGTGCTGGTTCCTGATGGCCTCAAGCGCCGGCCGGGCT

>NZ_CP014485|28|22|4786987-4787074|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCT	GTGGTGGGTAGTTCCGTACGGTTCGAAGGTGCTGGTTCCTGA
TGGCCTCAAGCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_008411113.1|4782511_4782718_-|acyl-CoA-carboxylase-subunit-epsilon	unknown	unknown	gnl|CDD|379386
NZ_CP014485.1|WP_003948352.1|4781633_4782233_-|septum-formation-inhibitor-Maf	unknown	unknown	gnl|CDD|178901
NZ_CP014485.1|WP_051701296.1|4780582_4781077_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404830.1|4788349_4789531_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|128563
NZ_CP014485.1|WP_003948346.1|4787160_4787949_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|181069
NZ_CP014485.1|WP_061404831.1|4793529_4795023_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223650
NZ_CP014485.1|WP_061404829.1|4778369_4780142_-|ATP-grasp-domain-containing-protein	unknown	unknown	gnl|CDD|227111
NZ_CP014485.1|WP_003948341.1|4792144_4793404_+|L,D-transpeptidase-family-protein	unknown	unknown	gnl|CDD|380079
NZ_CP014485.1|WP_008411123.1|4776043_4776619_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP014485.1|WP_008411092.1|4795876_4796920_+|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176186
NZ_CP014485.1|WP_059213032.1|4777006_4778089_-|hypothetical-protein	unknown	unknown	gnl|CDD|271332
NZ_CP014485.1|WP_015507808.1|4796945_4797479_-|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NZ_CP014485.1|WP_018894341.1|4782746_4784354_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_CP014485.1|WP_003948343.1|4791410_4791725_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003948348.1|4784677_4785562_+|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl|CDD|223417
NZ_CP014485.1|WP_015507806.1|4789617_4791159_+|histidine-ammonia-lyase	unknown	unknown	gnl|CDD|236484
NZ_CP014485.1|WP_075987139.1|4775011_4776010_+|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl|CDD|224268
NZ_CP014485.1|WP_061404832.1|4797573_4798677_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008411107.1|4785634_4786882_+|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NZ_CP014485.1|WP_003948339.1|4795076_4795766_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_008411113.1|4782511_4782718_-|acyl-CoA-carboxylase-subunit-epsilon	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	3.11458e-12
NZ_CP014485.1|WP_003948352.1|4781633_4782233_-|septum-formation-inhibitor-Maf	gnl|CDD|178901	PRK00148, PRK00148, Maf-like protein; Reviewed.	1.30384e-95
NZ_CP014485.1|WP_075987139.1|4775011_4776010_+|DeoR/GlpR-transcriptional-regulator	gnl|CDD|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	3.2323e-82
NZ_CP014485.1|WP_061404830.1|4788349_4789531_+|GGDEF-domain-containing-protein	gnl|CDD|128563	smart00267, GGDEF, diguanylate cyclase. Diguanylate cyclase, present in a variety of bacteria.	1.46917e-39
NZ_CP014485.1|WP_003948346.1|4787160_4787949_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|181069	PRK07657, PRK07657, enoyl-CoA hydratase; Provisional.	1.83306e-71
NZ_CP014485.1|WP_061404831.1|4793529_4795023_+|ABC-transporter-permease	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	2.3848e-16
NZ_CP014485.1|WP_061404829.1|4778369_4780142_-|ATP-grasp-domain-containing-protein	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NZ_CP014485.1|WP_003948341.1|4792144_4793404_+|L,D-transpeptidase-family-protein	gnl|CDD|380079	pfam17964, Big_10, Bacterial Ig domain. This entry represents a bacterial Ig-like domain found associated with transpeptidase domains.	1.95752e-72
NZ_CP014485.1|WP_008411123.1|4776043_4776619_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	9.07031e-11
NZ_CP014485.1|WP_008411092.1|4795876_4796920_+|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP014485.1|WP_059213032.1|4777006_4778089_-|hypothetical-protein	gnl|CDD|271332	cd14962, NHL_like_6, Uncharacterized NHL-repeat domain in bacterial proteins. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	0.00314742
NZ_CP014485.1|WP_018894341.1|4782746_4784354_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP014485.1|WP_015507808.1|4796945_4797479_-|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	3.17423e-41
NZ_CP014485.1|WP_015507806.1|4789617_4791159_+|histidine-ammonia-lyase	gnl|CDD|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NZ_CP014485.1|WP_003948348.1|4784677_4785562_+|biotin--[acetyl-CoA-carboxylase]-ligase	gnl|CDD|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	2.5269e-61
NZ_CP014485.1|WP_008411107.1|4785634_4786882_+|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	4.77436e-29
NZ_CP014485.1|WP_003948339.1|4795076_4795766_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	8.77408e-105

Protein sequences

>NZ_CP014485.1|WP_008411107.1|4785634_4786882_+|adenylate/guanylate-cyclase-domain-containing-protein
MTVDDTGSGTGTPRGPHGRDTGGGAGASDSAAPDGAAPGGGRGPASGAPERGLPDLPDRSERGGEPQEDGGQTEPKQDPLALRIEGLILGAERRYTPFQAARAAGVSMELASRFWRAMGFADIGQAKALTEADVLALRRLAGLVEAGLLSEAMAVQVARSTGQTTARLAEWQIDSFLEGLTEPPEPGMTRTEVTYPLIELLLPELEEFLVYVWRRQLAASTGRVIQVADDEEMVDRRFAVAFADLVGFTRLTRRMEEEELGELVEAFETTAADLVAARGGRLVKTLGDEVLFAADDAGTAAEIALLLIETMANDGSMPELRVGMTFGTITTRMGDVFGTTVNLASRLTSIAPKNAILVDSAFAAELVRTGEAPASEAEAAAAEEPGEYRFALQPMHQRPVRGLGAVEPWLLTRRD
>NZ_CP014485.1|WP_003948348.1|4784677_4785562_+|biotin--[acetyl-CoA-carboxylase]-ligase
MTPTDRPGRNGPAPWSDLSRPPLHESALRRALVRPGGLWTSLDVVQETGSTNADLAARAPELPEGTVLVAEEQLSGRGRLDRRWSAPARSGIFFSVLLRPTAPVEKWGWLPLLTGVAVASAVSRIAGVDTGLKWPNDLMVTVGDEERKAGGILAEMAGGGIVIGVGINVTLRADELPVPTAGSLGLAQAAVTDRDPLLRAVLRSLEEWYGRWQEAGGDAAASGVQAAYAAGCVTLGRAVRAELPGGEALTGEAVALDAEGRLVLATRDGVQRPVGAGDIVHLRPDGPPEGSGGE
>NZ_CP014485.1|WP_018894341.1|4782746_4784354_-|acyl-CoA-carboxylase-subunit-beta
MSAPENATTPPNPELHTTAGKLADLQRRIEEATHAGSARAVEKQHAKGKLTARERIGLLLDEGSFVELDEFARHRSTNFGLEANRPYGDGVVTGYGMVDGRPVAVFSQDFTVFGGALGEVFGQKIIKVMDFALKNGCPVIGINDSGGARIQEGVSALGMYGEIFRRNTHASGVIPQISLVVGPAAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNATSGVAHHMAGDEKDAIEYVKSLLSYLPSNNLSEAPVFAEEADLEISDEDRELDVIVPDSANQPYEMLRVIEHVVDDGEFLETQALFAPNIVTGFGRVEGHPVGVVANQPMQFAGCLDIDASEKAARFVRTCDAFNIPVLTFVDVPGFLPGVDQEHTGIIRRGAKLIYAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTLAQTPAEELEAVRTRLIQEYEEALLNPYTAAERGYIDAVIMPSDTRSHIVRGLRQLRTKRESLPPKKHGNIPL
>NZ_CP014485.1|WP_008411113.1|4782511_4782718_-|acyl-CoA-carboxylase-subunit-epsilon
MMIKVVRGNPTPEELAAALAVVRARAASAPGSDEGPRPPEGWSDPARIARTRMPAPGPRSWARTFWPS
>NZ_CP014485.1|WP_003948352.1|4781633_4782233_-|septum-formation-inhibitor-Maf
MSNRRVVLASASPARLGLLRQAGLAPEVIVSGVDEDALTADSPGALALVLAEAKAAAVALRPEAAGSVLIGCDSVLDLDGVALGKPADAEDATARWKAMRGRNGVLRTGHCVIDTASGRRASATASTTVRFGEPSDEEIAAYVASGEPLHVAGAFTLDGRSAPFIDGIDGDPGNVIGLSLPLLRRLLTELDLAITDFWE
>NZ_CP014485.1|WP_051701296.1|4780582_4781077_+|hypothetical-protein
MAAVAAGVVLFAEAFGVFMLLMTVGIVVENQSMSLDGLDPAMMSGGALGFGIFSAVFLAGCGLVLLLVGVRDRAPARFARILLVVVAVVHGVLGALTVGLVGWEAFAVLMVVLALIVFTLVAYGPGGRPQKPEAQQGAGSEQGEERTQKQESFPGEPGPKPAAS
>NZ_CP014485.1|WP_061404829.1|4778369_4780142_-|ATP-grasp-domain-containing-protein
MRKVLIANRGEIAVRVARACRDAGIESVAVYADPDRDALHVRAADEAFALGGDTPAASYLDIAKVLQAAADSGADAIHPGYGFLSENAEFAQAVLDAGLTWIGPPPQAIRDLGDKVAARHIAQRAGAPLVAGTPDPVSGSDEVVAFAEEHGLPIAIKAAFGGGGRGLKVARTLEEVPELYDSAVREAVAAFGRGECFVERYLDKPRHVETQCLADQHGNVVVVSTRDCSLQRRHQKLVEEAPAPFLSEAQVEQLYSASKAILKEAGYVGAGTVEFLVGNDGTISFLEVNTRLQVEHPVTEEVAGIDLVREMFRIADGEELGYGDPVLRGHSFEFRINGEDPGRGFLPAPGTVTVFDAPTGPGVRLDAGVESGSVIGPAWDSLLAKLIVTGATRQQALQRAARALAEFNVEGMATAIPFHRAVVADPAFAPELTGSSEPFTVHTRWIETEFVNEIKPFDAPADGDAEDESGRETVVVEVGGKRLEVSLPSSLGMSLARTGLAAGAKPKRRAAKKSGPAASGDSLASPMQGTIVKIAVEEGQEVKEGDLVVVLEAMKMEQPLNAHRSGTVKGLAAEVGASITSGAVICEIKD
>NZ_CP014485.1|WP_059213032.1|4777006_4778089_-|hypothetical-protein
MKQRPDRGARWGRLLAVTVVGALALFGPGSATAGAAGAPAEQPVTTELPYAYHSDLETDARHQRLYISDRVTGSVLVTDFDGQVVRKLDGLPGAADLALSKDNRTLYVALADGDAVVALDTATYRQKARYPTGEGTGPAQLALTGGKLWFSHGENWESSIGSLDLGGSKPVVRLNLTPEGYWGGPPRLTASPAAPGKLVAGEQYMSNAGVTVYDVGSGTPKPLVAQDNPGDLGALTGLALTPDGKSLLATGGYPYHHLSLDLDSLKVDHIYPTVAYPTASAVSARGAVAAGVDNSWGEDVYLFRQGESEPYRVVDFDPGTGSYLRPNGLAWSPDGTRLFAVTGTDGPHLSLRVVTAADPR
>NZ_CP014485.1|WP_008411123.1|4776043_4776619_-|TetR/AcrR-family-transcriptional-regulator
MPTETDQRPLRADARRNRERLLVEARRAFAAHGTDTSLEEIARRAGVGIGTLYRHFPHREALLSAVFADAVGELLERARVLLEAERPCAALVEWLRSLITHASEYQGLSGALMSASSGTGSELSRCSDPMRDAGAALLGRAQEAGVVRPDISIGDLLQLTNAIALAAEATPDEPELADRLLSLTLRGIRPD
>NZ_CP014485.1|WP_075987139.1|4775011_4776010_+|DeoR/GlpR-transcriptional-regulator
MFAAERRQLILEMVRANGAVSLRELARVVQTSEVTVRRDVRALEAEGLLDRRHGGAVLPGGFTRESGFPQKSHLASAEKTAIADLAAGLVGEGEAVVVGAGTTTQELARRLARVPGLTVVTNSLLVAQALAHANRVEVVMTGGTLRGSNYALVGSGAEQSLQGLRVSRAFLSGTGLTAERGLSTSNMLSASVDRALVQAAAEVVVLADHTKLGSDTMFQTVPTDLITRLVTDEPPAHEERAAGELQALADQGVQISLAGSHQPPAEAPPPPPAGGGRSGGGVRREAPLPGQRRTVHGAPPPGGPQLRGGAGPGSLGEQQLGERGRMADLRRR
>NZ_CP014485.1|WP_003948346.1|4787160_4787949_+|enoyl-CoA-hydratase/isomerase-family-protein
MPQTAEHLTITRHGHVAELALNRPEAMNAVSTDLARQLAAACEELARDQDVRVTVLTSTHPKAFCVGADLKERNRFTDAELVRQRPTARAAYTGVLELPMPTIAAVHGYALGGGYELALACDLIVADPTAVVGLPEVSVGVIPGGGGTQLLPRRVGAARAAELVFSARRVAGAEALALGLVDRLAEEGQDRAEALELATAMAAHSPVGLRNAKRALRLGQGLDLRAGLEVEDAAWRATAFSGDRAEGVAAFNEKRAPKWPGE
>NZ_CP014485.1|WP_061404830.1|4788349_4789531_+|GGDEF-domain-containing-protein
MGDDLRLRAVVGLAQAMAAVQGPREVWRAAALGACRALGGSFAALSVWEREQGRLRVLVNAGRLAAGEEEYPEAETYPVHQFPEITEFLHERWAGGGEPDAWVETADGRAEGRPGYCHQRVAALRRRGRGCCVVAPIVLHGHAWGELYVARDAGAEVFGRDDADFATVLAAVAAAGIVQCERLEEARRLAYTDALTGLANRRAVDARLDEAVEAHRAEGAVVSLVVCDVNGLKRVNDTHGHAVGDRLLERFGSLLSLCGAMLPGTLAARLGGDEFCLVSVGPEADEVVAVAEELCERAYGLATGEGVACGVASTGDAIGEVRSARRLFRLADAAQYRAKAVRARGPVVAGREAEPETGADAVLKLADTPPPEGGERRRLRGRRGGSGGAGAPG
>NZ_CP014485.1|WP_015507806.1|4789617_4791159_+|histidine-ammonia-lyase
MDMHTVVVGTSGTSAADVVAVARDGARVALSPEALAALAHAREAVDALAAKPEPVYGVSTGFGALATRHIGPELRTQLQRNIVRSHAAGMGPRVEREVVRALMFLRLKTLCSGYTGVRPEVAQTVADVLNAGITPVVHEYGSLGCSGDLAPLSHCALALMGEGDAEGPDGTVRPAAELLAEHGITPVELREKEGLALLNGTDGMLGMLVMALADLDRLYTTADITAALTLEALLGTDRVLAPELHAVRPHPGQAASAANMAAVLAGSGLVGGHQDDAPRVQDAYSVRCAPQVAGAGRDTLAHARLVAERELAAAVDNPLVIDGRVESNGNFHGAPVAYVLDFVAIAVADLASIAERRTDRLLDKNRSHGLPPFLADDPGVDSGLMIAQYTQAALVSELKRLAVPSSADSIPSSAMQEDHVSMGWSAARKLRTAVDALARVLAVELYAATRAVELRAGLTPAPASAAVIAALRAAGVEGPGPDRVLAPDLALTTEFVRSGRPVEAAEQHTGPLA
>NZ_CP014485.1|WP_003948343.1|4791410_4791725_-|hypothetical-protein
MSSTARRSLLTATTAATLLGALWFVPSANASGTAGDTAPQEERAATTAGSAAEPAGEELLLADSGSVDTTPYLVGGTAFLLVGAGFVAYSARRGPWVTEDAGLT
>NZ_CP014485.1|WP_003948341.1|4792144_4793404_+|L,D-transpeptidase-family-protein
MTDSKRRRALSAASALLGGVLVLTACGGGDDGGSGGGSSESREKSQAEVDEAAAKKTSAARIKITPKDGADNASINNDAEVSVTKGKLTDVSMKSADGTDVPGTFSADKTSWKPEGQLQRATVYKIAAEAADSEGRKAHENASFTTVSPDNSFIGNFTPEDGSTVGVGMPVSINFDKGITNKAAVQNGIKVSSSSGQEVVGHWFNEKRLDFRPEDYWAGNSTVTLKLDLDGVEGADGVYGVQQKTVTFKIARNQVSIVDAKTKTMKITRDGKTVKTIPISAGSPDNKTYEGRMVISEKFKETRMNGATVGFTDDDGKGEYDIKDVPHAMRLSTSGTFIHGNYWGDKSIFGNANTSHGCVGLADAKGANDASTPGAWFYNNSMVGDVVDVRNTGDKTIAPDNGLNGWNMDWAQWKAGSAV
>NZ_CP014485.1|WP_061404831.1|4793529_4795023_+|ABC-transporter-permease
MFLTYLRRELRRRRKAALVVASGLALGIALVIVVTSVTAGMQRAQDQVLGSLYGLGTDLTVTKARSAPADGERPERPTFDFDADEDGEEQSGERLVVQGLATLDAATVTTAAAQDGVARAAGGLSLTSISVDGQFRRGQVQQDDGSDGSATPPNGGPGGGGSGGPGGGSGGRVEGGGAAFGIDSFTVYGTDVTADGLGPLASSTLTEGRAFTKADTDAAVAVVDSGYAQQEKLAKGDKVTVGGTKFTVVGIATADSGQAAADVYLPLKRAQTLADAKDKITTVYVQAADSQQIGTLKTALTKKLPGTTVTSSADLADTVSGSLSTAASLAGTVGRWLSWTVLAAAFLVAGLLTTASVGRRVREFGTLKALGWRSGRVTRQIVGEAVVNGLIGGVLGIAVGLGAAYAITAAGPTLTAQLGSLGGGMGGGGMGGGMGRGPGGGSGAGAQSLDVALTAPVSATTLALAVGLAVAGGLVAGAFGGWRASRLRPADALRRVE
>NZ_CP014485.1|WP_003948339.1|4795076_4795766_+|ABC-transporter-ATP-binding-protein
MYRLSGVTKHYRRGKQTVAALDGVDLTLADGDRLVIQGPTGGGKSTLLQMLGGLDRPTSGTVELDGTDLAALPEARLTRVRAETIGFVFQSFNLIPTLTAQENVETALVPLGLRAADRRERAAEALASVGLGERVGHVPAELSGGQQQRVAIARALVKRPKVLLADEPTGNLDTATRDDIMELLDALWREHGLTFVMVTHDPALTRRADRLATLTGGSLALTENRADAS
>NZ_CP014485.1|WP_008411092.1|4795876_4796920_+|NAD(P)-dependent-alcohol-dehydrogenase
MTQTVPAYAAPAPGAPLERTTIERRTPGPHDVLIDIAYAGICHSDIHQARDGWAEGIFPMVPGHEIAGTVAAVGEAVTRFSVGDRVGVGCMVDSCRTCEFCLAGQEQNCANGSTGTYNAIGRDGEPTYGGYATHVVVDENFTVRIPDSLPLDVAAPLLCAGITVYSPLRHWQAGPGKKVAVVGLGGLGHMGVKIAHALGAEVTVLSQSLRKREDGLKLGADHYHATADGTVFDELAGTFDLIVSTVSAPLKLGGYLKLLRPDGALVNVGAPEEPVSLNLFSLIGGRKTLAGSNIGGIPETQEMLDFCAEHGLGAEIEVIRADQINEAYERVVNSDVRYRFVIDTATI
>NZ_CP014485.1|WP_015507808.1|4796945_4797479_-|DinB-family-protein
MSGIVVPVDGLAERVSPPVNGSERESLRGHLDFHRATLLAKCAGLTTEQLRTKSSPPSALSLLGLVRHMAEVERAWFRRTFAGEEIGLVWSPEGDFQVAYDAARADAGEAFAAWQAEVAHARRIEAAAASLDETAWSPRWEAEVSLRAIMLHLIHDYARHNGHADLLREGVDGAVGV
>NZ_CP014485.1|WP_061404832.1|4797573_4798677_-|hypothetical-protein
MELLWALMAVVMIGAVLGPVILRRRRGIRQVQPGTPEAADPAQYGFRPQETLDLRLPGPDQDLLDVLDVVQRTQDWRAASQLLAGTDKHGELRWQRVQAFAGAASLELQQRPGEGGRWLRDWRAQEPKDAGGAAVHAEFLVQQAWRSSTAGSDDFRIILEEARSAVAQAALLAPGDPVPYISELAVARGLGYTQQEFDQLWLKILDRAPAHMGAHLVALPYWSEKWHGSRQQSMAFAEAAAARAPGGSLLSALPLFSLYEHLPEVNLVRNFFQSQVFTRALEGAQFAAQSARQDDPVLPHVRHLLVFFLVSSERWGEAMHQLVRVDGYVGALPWTLSADPAAQFAVYRALAVGGYEANGGSPATLRG

Crispr_ID: NZ_CP014485_29

• CRISPR_ID: NZ_CP014485_29
• CRISPR_location: 5106989-5107627
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 10 spacers
• Cas_protein_info: Cas9_archaeal

Consensus repeat of NZ_CP014485_29

Consensus_repeat	Method
GTGGTCCCCGCGCGTGCGGGGGTGGTCCC	PILER-CR
GGGACCACCCCCGCACGCGCGGGGACCAC	CRISPRCasFinder
GGGACCACCCCCGCACGCGCGGGGACCAC	CRT

spacers of NZ_CP014485_29

>29.1|5107018|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
GAGAGGCAGGAAGCCTCCCCAGGGCCCACACC
>29.2|5107079|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
CTCGGCCGGTGCCCCCGCGTCCAGGCCGCCGG
>29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
ACCTCGGCGACGGCGAGCAGTACCAGGCGCGC
>29.4|5107201|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
TCTTCGTCGTCACGGCCCCGGAAGGGCCGGAC
>29.5|5107262|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
GTCACCGGATCGGATCCAGGGTCCGACGTGTT
>29.6|5107323|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
ATCGTGAACGACTTGCGGGGCTTCTGGGCGCC
>29.7|5107384|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
CCGAGTCCGAAGATGATTGCGACGGGCGCGTA
>29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
AGGCCGTCATCACCGACAACGAGGGCAAGGTT
>29.9|5107506|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT
TCGAGCGCCGGGAGATCAAGATCAGCGGCGTC
>29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT
ACTTCCCCCAGCACGTCCGCGACGGCCAGCTG

CRISPR arrays and Neighbor proteins around NZ_CP014485_29

CRISPR arrays

The CRISPR arrays of NZ_CP014485_29

>merge|NZ_CP014485|29|5106989-5107627|PILER-CR,CRISPRCasFinder,CRT
GGGGCTACCTCAGCATGCGCGGGGACCACGAGAGGCAGGAAGCCTCCCCAGGGCCCACACCGGGCCCACCCCCGCACGCGCGGGGACCACCTCGGCCGGTGCCCCCGCGTCCAGGCCGCCGGGGGACCACCCCCGCATGCGCGGGGACCACACCTCGGCGACGGCGAGCAGTACCAGGCGCGCGGGACCACCCCCGCACGCGCGGGGACCACTCTTCGTCGTCACGGCCCCGGAAGGGCCGGACGGGACCACCCCCGCACGCGCGGGGACCACGTCACCGGATCGGATCCAGGGTCCGACGTGTTGGGACCACCCCCGCACGCGCGGGGACCACATCGTGAACGACTTGCGGGGCTTCTGGGCGCCGGGACCACCCCCGCACGCGCGGGGACCACCCGAGTCCGAAGATGATTGCGACGGGCGCGTAGGGACCACCCCCGCACGCGCGGGGACCACAGGCCGTCATCACCGACAACGAGGGCAAGGTTGGGACCACCCCCGCACGCGCGGGGACCACTCGAGCGCCGGGAGATCAAGATCAGCGGCGTCGGGACCACCCCCGCACGCGCGGGGACCACACTTCCCCCAGCACGTCCGCGACGGCCAGCTGGGGACCACCCCCGCACGCGCGGGGACCAC

>NZ_CP014485|29|9|5106989-5107566|PILER-CR
GGGGCTACCTCAGCATGCGCGGGGACCAC	GAGAGGCAGGAAGCCTCCCCAGGGCCCACACC
GGGCCCACCCCCGCACGCGCGGGGACCAC	CTCGGCCGGTGCCCCCGCGTCCAGGCCGCCGG
GGGACCACCCCCGCATGCGCGGGGACCAC	ACCTCGGCGACGGCGAGCAGTACCAGGCGCGC
GGGACCACCCCCGCACGCGCGGGGACCAC	TCTTCGTCGTCACGGCCCCGGAAGGGCCGGAC
GGGACCACCCCCGCACGCGCGGGGACCAC	GTCACCGGATCGGATCCAGGGTCCGACGTGTT
GGGACCACCCCCGCACGCGCGGGGACCAC	ATCGTGAACGACTTGCGGGGCTTCTGGGCGCC
GGGACCACCCCCGCACGCGCGGGGACCAC	CCGAGTCCGAAGATGATTGCGACGGGCGCGTA
GGGACCACCCCCGCACGCGCGGGGACCAC	AGGCCGTCATCACCGACAACGAGGGCAAGGTT
GGGACCACCCCCGCACGCGCGGGGACCAC	TCGAGCGCCGGGAGATCAAGATCAGCGGCGTC
GGGACCACCCCCGCACGCGCGGGGACCAC

>NZ_CP014485|29|23|5106989-5107627|CRISPRCasFinder
GGGGCTACCTCAGCATGCGCGGGGACCAC	GAGAGGCAGGAAGCCTCCCCAGGGCCCACACC
GGGCCCACCCCCGCACGCGCGGGGACCAC	CTCGGCCGGTGCCCCCGCGTCCAGGCCGCCGG
GGGACCACCCCCGCATGCGCGGGGACCAC	ACCTCGGCGACGGCGAGCAGTACCAGGCGCGC
GGGACCACCCCCGCACGCGCGGGGACCAC	TCTTCGTCGTCACGGCCCCGGAAGGGCCGGAC
GGGACCACCCCCGCACGCGCGGGGACCAC	GTCACCGGATCGGATCCAGGGTCCGACGTGTT
GGGACCACCCCCGCACGCGCGGGGACCAC	ATCGTGAACGACTTGCGGGGCTTCTGGGCGCC
GGGACCACCCCCGCACGCGCGGGGACCAC	CCGAGTCCGAAGATGATTGCGACGGGCGCGTA
GGGACCACCCCCGCACGCGCGGGGACCAC	AGGCCGTCATCACCGACAACGAGGGCAAGGTT
GGGACCACCCCCGCACGCGCGGGGACCAC	TCGAGCGCCGGGAGATCAAGATCAGCGGCGTC
GGGACCACCCCCGCACGCGCGGGGACCAC	ACTTCCCCCAGCACGTCCGCGACGGCCAGCTG
GGGACCACCCCCGCACGCGCGGGGACCAC

>NZ_CP014485|29|4|5106989-5107627|CRT
GGGGCTACCTCAGCATGCGCGGGGACCAC	GAGAGGCAGGAAGCCTCCCCAGGGCCCACACC
GGGCCCACCCCCGCACGCGCGGGGACCAC	CTCGGCCGGTGCCCCCGCGTCCAGGCCGCCGG
GGGACCACCCCCGCATGCGCGGGGACCAC	ACCTCGGCGACGGCGAGCAGTACCAGGCGCGC
GGGACCACCCCCGCACGCGCGGGGACCAC	TCTTCGTCGTCACGGCCCCGGAAGGGCCGGAC
GGGACCACCCCCGCACGCGCGGGGACCAC	GTCACCGGATCGGATCCAGGGTCCGACGTGTT
GGGACCACCCCCGCACGCGCGGGGACCAC	ATCGTGAACGACTTGCGGGGCTTCTGGGCGCC
GGGACCACCCCCGCACGCGCGGGGACCAC	CCGAGTCCGAAGATGATTGCGACGGGCGCGTA
GGGACCACCCCCGCACGCGCGGGGACCAC	AGGCCGTCATCACCGACAACGAGGGCAAGGTT
GGGACCACCCCCGCACGCGCGGGGACCAC	TCGAGCGCCGGGAGATCAAGATCAGCGGCGTC
GGGACCACCCCCGCACGCGCGGGGACCAC	ACTTCCCCCAGCACGTCCGCGACGGCCAGCTG
GGGACCACCCCCGCACGCGCGGGGACCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_037845568.1|5094890_5096249_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238119
NZ_CP014485.1|WP_059213471.1|5105240_5105435_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404909.1|5096449_5098057_-|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|223704
NZ_CP014485.1|WP_003948082.1|5118976_5119327_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	Cas9_archaeal	cas9_archaeal	gnl|CDD|224321
NZ_CP014485.1|WP_061404914.1|5108749_5110015_-|6-phospho-beta-glucosidase	unknown	unknown	gnl|CDD|133432
NZ_CP014485.1|WP_037842601.1|5110069_5111359_-|ROK-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224851
NZ_CP014485.1|WP_010637964.1|5103981_5104263_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_037845564.1|5092544_5093486_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|275041
NZ_CP014485.1|WP_079076026.1|5098060_5100592_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|319004
NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase	unknown	unknown	gnl|CDD|376788
NZ_CP014485.1|WP_010637942.1|5121676_5121874_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404912.1|5105529_5106777_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP014485.1|WP_051701362.1|5100588_5101911_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_078850384.1|5103038_5104007_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404913.1|5107781_5108759_-|ATPase	unknown	unknown	gnl|CDD|225518
NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase	unknown	unknown	gnl|CDD|273828
NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein	unknown	unknown	gnl|CDD|369423
NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NZ_CP014485.1|WP_061404911.1|5102019_5103027_-|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	Cas9_archaeal	cas9_archaeal	2.6e-11	37.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_037845568.1|5094890_5096249_-|VWA-domain-containing-protein	gnl|CDD|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	1.22242e-18
NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	3.10217e-38
NZ_CP014485.1|WP_061404909.1|5096449_5098057_-|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.80318e-39
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	gnl|CDD|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	4.21562e-21
NZ_CP014485.1|WP_061404914.1|5108749_5110015_-|6-phospho-beta-glucosidase	gnl|CDD|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP014485.1|WP_037842601.1|5110069_5111359_-|ROK-family-transcriptional-regulator	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	9.97281e-32
NZ_CP014485.1|WP_061404911.1|5102019_5103027_-|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.5684e-91
NZ_CP014485.1|WP_037845564.1|5092544_5093486_+|methyltransferase-domain-containing-protein	gnl|CDD|275041	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system. Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).	1.62026e-79
NZ_CP014485.1|WP_061404912.1|5105529_5106777_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	6.75933e-08
NZ_CP014485.1|WP_061404913.1|5107781_5108759_-|ATPase	gnl|CDD|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	1.37737e-20
NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase	gnl|CDD|273828	TIGR01840, poly3-hydroxybutyrate_depolymerase_A_precursor, esterase, PHB depolymerase family. This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation].	6.51534e-74
NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein	gnl|CDD|369423	pfam07555, NAGidase, beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.	3.27285e-138
NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase	gnl|CDD|376788	pfam02446, Glyco_hydro_77, 4-alpha-glucanotransferase. These enzymes EC:2.4.1.25 transfer a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.	2.45652e-161
NZ_CP014485.1|WP_079076026.1|5098060_5100592_-|serine/threonine-protein-kinase	gnl|CDD|319004	pfam16918, PknG_TPR, Protein kinase G tetratricopeptide repeat. This domain is found at the C-terminus of protein kinase G and contains a tetratricopeptide repeat (TPR).	8.66228e-81

Protein sequences

>NZ_CP014485.1|WP_061404912.1|5105529_5106777_-|helix-turn-helix-domain-containing-protein
MPSDTPPDPFADALAFGQRMEVLRTRRGMSRPVLAGLLGMSPSWVKQVERGQIQMPKLPVVLRIAELLRVRDLADLTGDQTPSVELFIGPGHPRLPAVRDAVNALTLDDSDRSAPRSAHLAARLATAWSARHKAAHHRDVLGTLLPGLIRDAQLAVRQSNSSAERRTALATLSEVYALSQFFLAYQPDSALLWRVAERCMVAAQESEDPHAIGVAAWLAGEAHRDAAHFDAAQAVAEEALAFLADHRADGGPKMLAIAGALEAGAGFTAARRGDSGSAWGWWDRAQVAARALPVGYYHPVTSFSVPIMGAHAVTLAVELHAGGEAVRQAVAADATAIPSRPRLARHRIEEARAYRLDGQTEAALATLERAHHAAPETIRYNGYARRIVLEETESRQPARRRRAAALADQLGLLAA
>NZ_CP014485.1|WP_059213471.1|5105240_5105435_-|hypothetical-protein
MATTTRLPAPTTLSDAQLRGTACVWCGGQLATTTAVDLGIRPDPQFPWARWFPRACPPCHRART
>NZ_CP014485.1|WP_010637964.1|5103981_5104263_+|hypothetical-protein
MYTGSSRLNSSISAAESADPSVAAAAVTSFREAVAMSRSYRSRTSAGSSPPARNPLEAAVLASANDRYTAAASALSGCDRLSTSRAASDRSAT
>NZ_CP014485.1|WP_078850384.1|5103038_5104007_-|hypothetical-protein
MSRLLPVYTARIEAARANNRQGLPLGGAWLRNANDLMQEEMLPAAERLYQAEKERLRTDYATAQGFPWVAVGLGVLTVGALGGVQHALYRRTNRRFNVGLLGATAACGVLLVWVTAGHTLASAGLSDSYERGVRSLNVLNDARISALKARGGENLTLVARGAVTVPAGQKFAGQDSYDVAYRAEMARLLGPEGGGRSGGLLGQALELADDPAGGDPVRAAADRAGEWRERHLKAREYDEAGDYEQALRRVIGAEKDEATGASFDRLDAALEKALAHEQGEFERAARTGGGALTGLVAGALVLAALGTAGAGVGIARRLAEYR
>NZ_CP014485.1|WP_061404911.1|5102019_5103027_-|glutamate-ABC-transporter-substrate-binding-protein
MNRSDRERPRPGPRLRGWGGVTAMAVACVLTAALVLLPLQRVSEATLGMDDTAPRGPAAAEPARAEACEKPEASSARPSKAEGATLERIKSRTDKPRKLIVGIDQNSYRWGYRDPATGSLEGFDIDLVRAIAEELMGDPEAVVFRAIPTNRRVQAIDSGEVDMVVRTMTITCDRIKEVAFSTAYFETGQQLLVPKGSRITGHDTSLKGRKVCAAAGSTALTELEREAHGADISTTVPNQLDCLVRLQLGEVDAVVTDSALAAGQAAQDPMVELVGEPFTEEFYGVAMHKDAKDLVARVNQVLVEYRKDGWERSYDKWLKDGMGKSPGPPPATYRD
>NZ_CP014485.1|WP_051701362.1|5100588_5101911_-|hypothetical-protein
MGVARADPGAGGSGGTAGGPVLDRDEADRALARLVAEREAVETSLLALQDHAGRRLLEGAGLTGTTAERWRATEADITRLWAYFDAYSAAVTEAREVRARRRWPGREELAALSELLRGASVTVPGTPGGGPGAAVLAEQLSLTELVDRMNTLYAESLAVVVAADAVWSALPARIDLLAAEQRRTRSLAGSVGVLPGEHPAGDDLERIGRVLTVLREQVVSDPLSFWVASDGGATPGAGRPDTRRYDREARALEEVRREIEAVLQVRQDAEARLARLRDVLSRADRTLAEARTARGEVLAKIAASEVPAVSGPPSALKEQVAAAADHRRHGRWHRLSPLLEALERRADDELERARASLTAVTAPLAVRAELRGRLDAYRAKVSRLGLAEDPVLAERYDAARRVLWSAPCDLRVAEEAVLRFQRAAAEALAPGAGDDGRGGA
>NZ_CP014485.1|WP_079076026.1|5098060_5100592_-|serine/threonine-protein-kinase
MRRSCQRPGCAGAYEDVGGGELYCDECGMAPVVSPDGSLSSPPTGVAAGGSARSGRSARGSAGSARGSGSARTAASTGSRSSRRSVSGQLSRSQSGRATTRSVSVRSSASNSASQRGRLGAGLVAVPDVPRPDPRTAVASDPRVPERKRFCSRAECGAPVGRSRGERPGRTEGFCTKCGHPYSFVPKLRAGEVVHGQYEVVGCLAHGGLGWVYLAVDRAVSDRWVVLKGLLDTGDQDAMEAAISERRFLAEIEHANIVRIYNFVEHLDQRTGSLDGYIVMEYVGGKSLKELANERRTPEGRRDPLPVEQACAYGIEALEALGHLHSRNLLYCDFKVDNAIQTEGQLKLIDMGAVRRMDDEESAIYGTVGYQAPEVATHGPSVASDLYTVARTLAVLTFDFQGYTNVYADSLPDPHDVPVLWTYESFYRLLIRATDPDPTRRFATAEEMAEQLTGVLREVVALQSGRPHPAVSTLFGPELRVTDTEVVPDDGVVSRLGERPAPVARALRRARTAPELTAGTPPAHGAPDPAAAALALPMPRVDPGDPNAGFLAGLAAAAPGELASALGLASVDSPELRLRRLRAELERGRVAAAEQGLRELESYVPDDWRLVWYRGVTSLASGDFEGAALSFDALYDAFPGEPAPKLALGLAAEVLGQGENAAEYYRLVWSCDPTFVSAAFSLARVQWASGLRQEAVRTLESVPEASVHHTAARVAAIRVRLRRRDPTEPLLPDLTAAASQLEALEGLGLDPVRRERLATEVLGTALDWVLSGSPGQTPDGASGSGLRAGGTARTVLLGSELDERGLRFGLERAYRTLARLARRGEERIELVERANRFRPRTMV
>NZ_CP014485.1|WP_061404909.1|5096449_5098057_-|protein-phosphatase-2C-domain-containing-protein
MSRIPQLSACPSCEEPLEPADHFCGACGFDLSSVPEPPSGRPGAGPPDGPAPQGATGTPVAWPAAPPLPPSAAPGETSPLHRAEDLPGTDSAGAPLPGAPAEPPPPAGSAAPEGPAPAGTPAAPAPAAGQPWGAPPATGTRVPEARSGGAGPAAEQGDFALAEPGAVPAPPVPPAPPVPPVPEAPPAPPAGNGPPTLVDPAPAVPPAGEGAKAPSPGEDAPADPREAVAASGGGGKSCVACRAGQVDADGYCENCGHAQPRERDHMEEEIAGVAAVSDRGLRHHRNEDAFALAEAALPDGSPAVVAIVCDGVSSATRPDEASLAASRAASEALVASLGQGTHPQTAMHEAIVAAARAVDDLAEERPADAEAPRQNAPACTIVGAVAAGGLLVVGWIGDSRVYWVPADREGPVARLTEDDSWAAQMVAAGLMSEAEAYADSRAHAITGWLGADAYELDPHTASFKPDRPGVAVVCSDGLWNYAESAEDMAAALPADALTRPLHSAQVLVGHALDGGGHDNVTVAVVPFDVRPQEGS
>NZ_CP014485.1|WP_037845568.1|5094890_5096249_-|VWA-domain-containing-protein
MANFAKPDVPRFAVEVYQNEFLPEGGREVNAIVTVTATGGGTLGGLPAHDGAVGTASAVALMVDCSGSMDHPSSKMRHARDATRTAVAALRDGTRFAVIAGTHVAREVYPGGGRLATADDRTREEAREAVLRLRAGGGTAIGSWLRLAEQLLTSEPAGVRHGILLTDGRNEHETPEELRAALDLCAGRFTCDARGVGTDWEVKEVTGIATSLLGSADIVADPAGLARDFRTMMESAMGKEVADVALRLWTPQGAEVTFVKQVAPSVSDLTGRRSAAGPRSGDYPTGSWGDESRDYHVCVRVPAADVGREMLAARVSLVVPQPDGGATPVAQGLVRAVWTDDTAVSTSLNPQVAHYTGQAELAQAIQDGLAARKAGDVDGATAKLGRAVQLAGASGHADTAKLLAKVVDVIDEANGTVRLKARVEDADEMTLDTRSTKTARLHQRPPAPRSGT
>NZ_CP014485.1|WP_037845564.1|5092544_5093486_+|methyltransferase-domain-containing-protein
MARARARLSQDIANQGGFDGEPEWREAFAAVPRHLFVPSYFGPSAGGWRRMWGEDPDPVRRLAWLEGVYTDTPLATRLRDGELLSSSSQPSLMAKMLADLRVHEGDRVLEIGAGTGWNAALLAYRLGSAHVTTVDLDPDITDSARRHLEAAGLHPHVVTGDGARGCRADAPYDRVLATCALDTVPRPWLEQTRPGGLILTPFATGLVRLTVHGPDRAEGRFLPTPAYFVPLRGTEPRAARDLPTDGIARHLLNNEGFRFLLTLTAGRLSPAEALEVWQRESHPVRERFGLTADSGTLTAWLDDPAGPDRWQLV
>NZ_CP014485.1|WP_061404913.1|5107781_5108759_-|ATPase
MGLSGAVLAIDAGNSKTDVAVVTADGEVAGTARGGGFRPPATGVEAAVDTLAEAVARAQEAAGHLPVAQVSACLANADLPVEEEQLSAAIAARGWGASVEVRNDTFAVLRAGLLEDAAPRGVAVVCGAGINCAGMLPDGRTARFPALGRVSGDWGGGGGLAEEALWHAARAEDGRGAPTELARALPEHFGLGSMYALIEALHLGRVPAGRRHELTPVLFTVAEAGDPVASGLVDRLADEVANMAAVALGRLGLLDSPAPVLLGGSILAARRPGLDAGVRGELSRRAPLAEVRVVEAAPVLGAVLLGMDAVGAGVGAYGRVRGWYG
>NZ_CP014485.1|WP_061404914.1|5108749_5110015_-|6-phospho-beta-glucosidase
MKLTVVGGGSTYTPELIDGFARLRDTLPLTELVLVDPDAGRLELVGGLARRIFARQGHPGAITTTGDLDAGVEGADAVLLQLRVGGQAARQRDESWPLECGCVGQETTGAGGLAKALRTVPVVLDIAERVRRTNPDAWIIDFTNPVGIVTRALLQAGHKAVGLCNVAIGFQRKFARLLDVAPAEVHLGHVGLNHLSWETSVRLGGPTGEDVLPRLLTEHGDAIAADLHLPRPLLDRLGVVPSYYLRYFYAHDVVVDELRTGPSRAEKVAAMERELLELYADPALDEKPELLSQRGGAFYSEAAVDLAAALLGRGGSPLQVVNARNDGTLPFLPDDAVVEVQAEVGPEGARPLAVPALDPLYAGLVQHVTAYEDLALRAALEGGRDRVFAALLAHPLIGQYDQAETLTDLLLSHNQEHLPWA
>NZ_CP014485.1|WP_037842601.1|5110069_5111359_-|ROK-family-transcriptional-regulator
MVAGTPRVLRVMNERATLDLLTEHGALSRARIGALTGLSKPTVSQLLARLEAAGLVGPAGTSEGRPGPGARLYALRGEVAYVAALDVRPGRIRAAVADVTGTVLATHTLATPARPGPGGVPAQLTAALDGAARAAGTERPALRRVVVGTPGAFDPRTGRLRYAGHLAGWHSPGLLAEVAAALHPVPVEYENDVNLAAVAERRLGAARGHEDFVLLWNGTGLGAALVIGGRLHRGWTGGAGEIGFLPVAGTPLVRGVARTGSGGFQELAGAQALPRLAGELGVAVPQAGPEGADPADGEAVAATLLRTAAEAYTRPGGDPAPGAAEPPHEGTSSPHAGPAALLRAYAVRLATGIASLVAVLDPAVIVLTGRVLAAGGEPLLRLTEAELAELAPSRPRLLAGEVTGDPVVRGGLEAALTTVRDEVFDTAAL
>NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein
MFPSAPAAGREDTVTLEEAQERATDAAGWVSENWSTWLETGLRILLIIVVAAALRMVIRKTITNLIDRMNRTASAVDGTALGGLLVNAERRRQRSQAIGSVLRSVASFLIVGTAALMILDTFKINLAPLLASAGVAGVAIGFGARNLVTDFLSGVFMILEDQYGVGDTIDAGVATGEVVEVGLRVTKLRGPNGAVWYVRNGEVKRIGNLSQGWSTAAVEVTVRSDEDLDKVRDTLTEVGAQIAKDEPWNERLWGPVEVLGLDSVLLDSMVVGVSAKTMPGQDVAVERELRWRIKKAFDAAGISIVGGPAELAEEDAADPSAGMAAPSAYASATSPQSLAASPIPPASGPRLGK
>NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease
MPHVLVLNASYEPLGVVPLRRALVLVLESKAVCLEESGAFLHSESRTVPAPSVVRLKRFVKVPYRGPVPLTRRALFARDGGRCVYCGGVATSVDHVIPRSRGGLHVWDNVVASCRRCNHVKADRHLMELGWRLRNKPAPPTGLAWRIIGTGHRDPRWLPYLQPFGGDDALARIENVGAGGEAVAVRPARAGA
>NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase
MVTLAGVAGPESVTAPARAASLTEVTGFGSNPGNLRMFRYVPDGLPAGRPLVVAMHGCTQSAGGFDDETGWTKWADQWGFALVLPQQQSANNLNSCFNWFEAGDIRRDAGEALSIKQMTDRMKADVGSDPARVHATGLSAGAAMTNVMLAAYPDVFASGAPVAGLPYACATSVVAAYSCMNPGSNLTPAAWAAKVRDAYPGYAGPWPAVSVWQGTTDTTVVPANLTETVEQWTAVHGTDTTPDATGTVGGYPHAVYRDGDGRDVVETYTITGMGHGQPVDPGSGAEQCGTAGAYILDVNICAAYHIGRFWGLAEDGGGTDPGTPAQRAVIPSTAADDGYVKASASGTGAAVGALEGTMGAAVGRGTDGQHNRTLLSFDTSAVPDDATITRAYVTVSRASGSGDPWAGGNRLLIDVRSGCFGASCATAADDWAAPATASGAAELARFTSGRADSTAFTEVNRTGPTQLRLRLADAPASTAYLFLRTGAEAKLTVEWE
>NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein
MQLRRSRTAAALAVAVIAGTLGGAPTALAAPPAPDPATAADEAPDDAKGETAGLPSVWPRPQSLRAADGKVALGSRVVLVAPLGTDPYALKALREVLREAGVRDVDEVSAEGDVPAGATPVVRVGGESAARPGAGGAGLEKTLRALGASARGDLPQGGYRLAAGQADGRPTVAMAGVGEDGLFHAVQTLRQLVRDGVVPGVVVRDWPGTPVRGLSEGFYGTPWTTEQRLGQLDFLGRTKQNHYLYAPGDDLFRQARWREPYPAGQRAAFRALAERARENHVTLAWAVAPGQAMCLASEDDVKALNRKIDAMWALGARAFQLQFQDVSYSEWHCGEDEAEFGSGPAAAARAQARVANAVAAHLAERHPGSRPLSLMPTEYYQKGATEYRRKLAAELEADVQVAWTGVGVVPRTITGRELAGTREVLGHPLVTLDNYPVNDYAQDRIFLGPYTGREPAVATGSAALIATAMEQPAASRIPLFTSGDYAWNPKDYRPMESWQAAMDTLAGEDPETREAVRALARNTASSVLGADESAYLRPLLAKFWATRADAARAAGRPGTEAADAAARAAKELRAAFSVMRATPERLDGGGSGLGEEVRPWSEQLARFGHAGELAVDLLAAQARGDGTAAWHAERALRAVRAETSRNKVTVGDGVLGPFLDQVEKTADSWHGTVGGDGEKVADTGSAYTVALPRVRPLAGVTVRTDPGVSGLVEARVPGKGWQPVTRLEPGGWTDVESRGLRADALRVTGPEAERVDRLVPWYEDGAEAALRLGRGEADAEIGGGTSEVTARLTAHRPGTVRGALKAKTPKGIQVSAPGESVLPRGTEVRIPVSVRVADGVRPGSYEVPVEFGGRSATLTVRAFPPTDDRDLVRSGKATSSADETEDFPARAAADGDPESRWSSPAEDNAWWQTELPEPARVGRVELHWQDAYAAAYRVQVSEDGRIWRTAATVKDGKGGRERVGLDAKNVRFLRVQGDKRATEYGYSLFSVEAYAVTEKEKSKDKGKGDGKAEEKPGRD
>NZ_CP014485.1|WP_003948082.1|5118976_5119327_+|hypothetical-protein
MAASAHLLLSALSKRPELHDLPAIPSPTTLAGRPDDPFDPDTVDYSLVSHPDSGLEGSCAYGLSEPPLTSEPPLADAAPLTSEPPLPDTAPLTSEPAAAAAVVAEDALLGAVSSGG
>NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase
MALSRLAELHGVATSYSPSPDRTVPAAESAVVAALAALGVDASSPEAIRAALEKAEAGQAARLLPPTVVLRSAAPSADPRTAPELAALPPGTRVRLTRDPDPVPARPAPAGGRDAGEAVRRAAPVGEAPPPAWNWTVPLVPAATAPPPPAGSALPPAADVLWAVPFGVHRIEATTPDGRTATSHLVIAPDHIRGPESRAWGLLVQLYSLLSHRSWGMGDLGDLAELATWAGRVHGAGFVQVNPLHAAVPGTPTDPSPYRPSSRRFPDPVHLRVEAIPEYTALSADVRPHLDGLLRRAAELRGRVLSGEALIDRDAVWELKREALERLCAVPLPPGRQAAYEDFTAAHGQALTDHATWAALTERHGPHWSEWPAPLTDPRSRQTAAARTELAARVDFHRRLAWYTDTQLAEAQRAAREAGMAVGLVHDLAVGVHPDGSDAWSQQDVFAAGMSVGAPPDAFNALGQDWGLPPWRPDRLAESGYAPYRGLLRSLLRNAGALRIDHVMGLFRLWWVPVGAPPTDGTYVHYDAEAMLAVLALEAHRADAVVIGEDLGTVEPGVRETLQRHGVLGTSVLWFERDWDGTGLPLPAEAWRASCVATATTHDLPSTASRLTGDHVRLRHRLGLLTRPLAEEEAEEAAATATWLTVLDGLGLMGAAPGGHLPGAAPDEEAAVLAVHRFLLRTPARMIGVWLPDGTGDRRPQNLPGTWDQYPNWRLPVADAQGHPVTLEQLTASPRVARLLRTVATEDQTPAPMVRTAPPDARPV
>NZ_CP014485.1|WP_010637942.1|5121676_5121874_+|hypothetical-protein
MVAGTTLTTLLMTSPALALTRDDGDDPGPGLSVVETLGLYVALPIVLFLVIAGLVMVMDKSGKRS

Crispr_ID: NZ_CP014485_30

• CRISPR_ID: NZ_CP014485_30
• CRISPR_location: 5113623-5113767
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: Cas9_archaeal

Consensus repeat of NZ_CP014485_30

Consensus_repeat	Method
GGCCTCAAGCGCCGGCCGGGCTG	CRISPRCasFinder

spacers of NZ_CP014485_30

>30.1|5113646|39|NZ_CP014485|CRISPRCasFinder
AATTTGGCTGGGGTCCGGCTTCGTGTGCCGGTTCACGAT
>30.2|5113708|37|NZ_CP014485|CRISPRCasFinder
GAAAGGTGGCCTCAAGCGCCGGCCGGGCTTGAAAGGT

CRISPR arrays and Neighbor proteins around NZ_CP014485_30

CRISPR arrays

The CRISPR arrays of NZ_CP014485_30

>merge|NZ_CP014485|30|5113623-5113767|CRISPRCasFinder
GGCCTCAAGCGCCGGCCGGGCTGAATTTGGCTGGGGTCCGGCTTCGTGTGCCGGTTCACGATGGCCTCAAACGCCGGCCGGGCTGGAAAGGTGGCCTCAAGCGCCGGCCGGGCTTGAAAGGTGGCCTCAAGCGCCGGCCGGGCTT

>NZ_CP014485|30|24|5113623-5113767|CRISPRCasFinder
GGCCTCAAGCGCCGGCCGGGCTG	AATTTGGCTGGGGTCCGGCTTCGTGTGCCGGTTCACGAT
GGCCTCAAACGCCGGCCGGGCTG	GAAAGGTGGCCTCAAGCGCCGGCCGGGCTTGAAAGGT
GGCCTCAAGCGCCGGCCGGGCTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061404912.1|5105529_5106777_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP014485.1|WP_030308893.1|5124167_5124557_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003948082.1|5118976_5119327_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	Cas9_archaeal	cas9_archaeal	gnl|CDD|224321
NZ_CP014485.1|WP_061404914.1|5108749_5110015_-|6-phospho-beta-glucosidase	unknown	unknown	gnl|CDD|133432
NZ_CP014485.1|WP_037842601.1|5110069_5111359_-|ROK-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224851
NZ_CP014485.1|WP_059213471.1|5105240_5105435_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008414245.1|5123183_5124095_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NZ_CP014485.1|WP_078842902.1|5134858_5135686_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_010637964.1|5103981_5104263_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_010637942.1|5121676_5121874_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NZ_CP014485.1|WP_061404917.1|5135887_5136367_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_078850384.1|5103038_5104007_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404913.1|5107781_5108759_-|ATPase	unknown	unknown	gnl|CDD|225518
NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase	unknown	unknown	gnl|CDD|273828
NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein	unknown	unknown	gnl|CDD|369423
NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase	unknown	unknown	gnl|CDD|376788
NZ_CP014485.1|WP_061404911.1|5102019_5103027_-|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NZ_CP014485.1|WP_061404916.1|5124609_5127627_-|DNRLRE-domain-containing-protein	unknown	unknown	gnl|CDD|379232

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	Cas9_archaeal	cas9_archaeal	2.6e-11	37.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_061404912.1|5105529_5106777_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	6.75933e-08
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	gnl|CDD|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	4.21562e-21
NZ_CP014485.1|WP_061404914.1|5108749_5110015_-|6-phospho-beta-glucosidase	gnl|CDD|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP014485.1|WP_037842601.1|5110069_5111359_-|ROK-family-transcriptional-regulator	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	9.97281e-32
NZ_CP014485.1|WP_008414245.1|5123183_5124095_+|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.29595e-45
NZ_CP014485.1|WP_061404911.1|5102019_5103027_-|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.5684e-91
NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	3.10217e-38
NZ_CP014485.1|WP_061404913.1|5107781_5108759_-|ATPase	gnl|CDD|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	1.37737e-20
NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase	gnl|CDD|273828	TIGR01840, poly3-hydroxybutyrate_depolymerase_A_precursor, esterase, PHB depolymerase family. This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation].	6.51534e-74
NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein	gnl|CDD|369423	pfam07555, NAGidase, beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.	3.27285e-138
NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase	gnl|CDD|376788	pfam02446, Glyco_hydro_77, 4-alpha-glucanotransferase. These enzymes EC:2.4.1.25 transfer a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.	2.45652e-161
NZ_CP014485.1|WP_061404916.1|5124609_5127627_-|DNRLRE-domain-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	0.000167981

Protein sequences

>NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease
MPHVLVLNASYEPLGVVPLRRALVLVLESKAVCLEESGAFLHSESRTVPAPSVVRLKRFVKVPYRGPVPLTRRALFARDGGRCVYCGGVATSVDHVIPRSRGGLHVWDNVVASCRRCNHVKADRHLMELGWRLRNKPAPPTGLAWRIIGTGHRDPRWLPYLQPFGGDDALARIENVGAGGEAVAVRPARAGA
>NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein
MFPSAPAAGREDTVTLEEAQERATDAAGWVSENWSTWLETGLRILLIIVVAAALRMVIRKTITNLIDRMNRTASAVDGTALGGLLVNAERRRQRSQAIGSVLRSVASFLIVGTAALMILDTFKINLAPLLASAGVAGVAIGFGARNLVTDFLSGVFMILEDQYGVGDTIDAGVATGEVVEVGLRVTKLRGPNGAVWYVRNGEVKRIGNLSQGWSTAAVEVTVRSDEDLDKVRDTLTEVGAQIAKDEPWNERLWGPVEVLGLDSVLLDSMVVGVSAKTMPGQDVAVERELRWRIKKAFDAAGISIVGGPAELAEEDAADPSAGMAAPSAYASATSPQSLAASPIPPASGPRLGK
>NZ_CP014485.1|WP_037842601.1|5110069_5111359_-|ROK-family-transcriptional-regulator
MVAGTPRVLRVMNERATLDLLTEHGALSRARIGALTGLSKPTVSQLLARLEAAGLVGPAGTSEGRPGPGARLYALRGEVAYVAALDVRPGRIRAAVADVTGTVLATHTLATPARPGPGGVPAQLTAALDGAARAAGTERPALRRVVVGTPGAFDPRTGRLRYAGHLAGWHSPGLLAEVAAALHPVPVEYENDVNLAAVAERRLGAARGHEDFVLLWNGTGLGAALVIGGRLHRGWTGGAGEIGFLPVAGTPLVRGVARTGSGGFQELAGAQALPRLAGELGVAVPQAGPEGADPADGEAVAATLLRTAAEAYTRPGGDPAPGAAEPPHEGTSSPHAGPAALLRAYAVRLATGIASLVAVLDPAVIVLTGRVLAAGGEPLLRLTEAELAELAPSRPRLLAGEVTGDPVVRGGLEAALTTVRDEVFDTAAL
>NZ_CP014485.1|WP_061404914.1|5108749_5110015_-|6-phospho-beta-glucosidase
MKLTVVGGGSTYTPELIDGFARLRDTLPLTELVLVDPDAGRLELVGGLARRIFARQGHPGAITTTGDLDAGVEGADAVLLQLRVGGQAARQRDESWPLECGCVGQETTGAGGLAKALRTVPVVLDIAERVRRTNPDAWIIDFTNPVGIVTRALLQAGHKAVGLCNVAIGFQRKFARLLDVAPAEVHLGHVGLNHLSWETSVRLGGPTGEDVLPRLLTEHGDAIAADLHLPRPLLDRLGVVPSYYLRYFYAHDVVVDELRTGPSRAEKVAAMERELLELYADPALDEKPELLSQRGGAFYSEAAVDLAAALLGRGGSPLQVVNARNDGTLPFLPDDAVVEVQAEVGPEGARPLAVPALDPLYAGLVQHVTAYEDLALRAALEGGRDRVFAALLAHPLIGQYDQAETLTDLLLSHNQEHLPWA
>NZ_CP014485.1|WP_061404913.1|5107781_5108759_-|ATPase
MGLSGAVLAIDAGNSKTDVAVVTADGEVAGTARGGGFRPPATGVEAAVDTLAEAVARAQEAAGHLPVAQVSACLANADLPVEEEQLSAAIAARGWGASVEVRNDTFAVLRAGLLEDAAPRGVAVVCGAGINCAGMLPDGRTARFPALGRVSGDWGGGGGLAEEALWHAARAEDGRGAPTELARALPEHFGLGSMYALIEALHLGRVPAGRRHELTPVLFTVAEAGDPVASGLVDRLADEVANMAAVALGRLGLLDSPAPVLLGGSILAARRPGLDAGVRGELSRRAPLAEVRVVEAAPVLGAVLLGMDAVGAGVGAYGRVRGWYG
>NZ_CP014485.1|WP_061404912.1|5105529_5106777_-|helix-turn-helix-domain-containing-protein
MPSDTPPDPFADALAFGQRMEVLRTRRGMSRPVLAGLLGMSPSWVKQVERGQIQMPKLPVVLRIAELLRVRDLADLTGDQTPSVELFIGPGHPRLPAVRDAVNALTLDDSDRSAPRSAHLAARLATAWSARHKAAHHRDVLGTLLPGLIRDAQLAVRQSNSSAERRTALATLSEVYALSQFFLAYQPDSALLWRVAERCMVAAQESEDPHAIGVAAWLAGEAHRDAAHFDAAQAVAEEALAFLADHRADGGPKMLAIAGALEAGAGFTAARRGDSGSAWGWWDRAQVAARALPVGYYHPVTSFSVPIMGAHAVTLAVELHAGGEAVRQAVAADATAIPSRPRLARHRIEEARAYRLDGQTEAALATLERAHHAAPETIRYNGYARRIVLEETESRQPARRRRAAALADQLGLLAA
>NZ_CP014485.1|WP_059213471.1|5105240_5105435_-|hypothetical-protein
MATTTRLPAPTTLSDAQLRGTACVWCGGQLATTTAVDLGIRPDPQFPWARWFPRACPPCHRART
>NZ_CP014485.1|WP_010637964.1|5103981_5104263_+|hypothetical-protein
MYTGSSRLNSSISAAESADPSVAAAAVTSFREAVAMSRSYRSRTSAGSSPPARNPLEAAVLASANDRYTAAASALSGCDRLSTSRAASDRSAT
>NZ_CP014485.1|WP_078850384.1|5103038_5104007_-|hypothetical-protein
MSRLLPVYTARIEAARANNRQGLPLGGAWLRNANDLMQEEMLPAAERLYQAEKERLRTDYATAQGFPWVAVGLGVLTVGALGGVQHALYRRTNRRFNVGLLGATAACGVLLVWVTAGHTLASAGLSDSYERGVRSLNVLNDARISALKARGGENLTLVARGAVTVPAGQKFAGQDSYDVAYRAEMARLLGPEGGGRSGGLLGQALELADDPAGGDPVRAAADRAGEWRERHLKAREYDEAGDYEQALRRVIGAEKDEATGASFDRLDAALEKALAHEQGEFERAARTGGGALTGLVAGALVLAALGTAGAGVGIARRLAEYR
>NZ_CP014485.1|WP_061404911.1|5102019_5103027_-|glutamate-ABC-transporter-substrate-binding-protein
MNRSDRERPRPGPRLRGWGGVTAMAVACVLTAALVLLPLQRVSEATLGMDDTAPRGPAAAEPARAEACEKPEASSARPSKAEGATLERIKSRTDKPRKLIVGIDQNSYRWGYRDPATGSLEGFDIDLVRAIAEELMGDPEAVVFRAIPTNRRVQAIDSGEVDMVVRTMTITCDRIKEVAFSTAYFETGQQLLVPKGSRITGHDTSLKGRKVCAAAGSTALTELEREAHGADISTTVPNQLDCLVRLQLGEVDAVVTDSALAAGQAAQDPMVELVGEPFTEEFYGVAMHKDAKDLVARVNQVLVEYRKDGWERSYDKWLKDGMGKSPGPPPATYRD
>NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase
MVTLAGVAGPESVTAPARAASLTEVTGFGSNPGNLRMFRYVPDGLPAGRPLVVAMHGCTQSAGGFDDETGWTKWADQWGFALVLPQQQSANNLNSCFNWFEAGDIRRDAGEALSIKQMTDRMKADVGSDPARVHATGLSAGAAMTNVMLAAYPDVFASGAPVAGLPYACATSVVAAYSCMNPGSNLTPAAWAAKVRDAYPGYAGPWPAVSVWQGTTDTTVVPANLTETVEQWTAVHGTDTTPDATGTVGGYPHAVYRDGDGRDVVETYTITGMGHGQPVDPGSGAEQCGTAGAYILDVNICAAYHIGRFWGLAEDGGGTDPGTPAQRAVIPSTAADDGYVKASASGTGAAVGALEGTMGAAVGRGTDGQHNRTLLSFDTSAVPDDATITRAYVTVSRASGSGDPWAGGNRLLIDVRSGCFGASCATAADDWAAPATASGAAELARFTSGRADSTAFTEVNRTGPTQLRLRLADAPASTAYLFLRTGAEAKLTVEWE
>NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein
MQLRRSRTAAALAVAVIAGTLGGAPTALAAPPAPDPATAADEAPDDAKGETAGLPSVWPRPQSLRAADGKVALGSRVVLVAPLGTDPYALKALREVLREAGVRDVDEVSAEGDVPAGATPVVRVGGESAARPGAGGAGLEKTLRALGASARGDLPQGGYRLAAGQADGRPTVAMAGVGEDGLFHAVQTLRQLVRDGVVPGVVVRDWPGTPVRGLSEGFYGTPWTTEQRLGQLDFLGRTKQNHYLYAPGDDLFRQARWREPYPAGQRAAFRALAERARENHVTLAWAVAPGQAMCLASEDDVKALNRKIDAMWALGARAFQLQFQDVSYSEWHCGEDEAEFGSGPAAAARAQARVANAVAAHLAERHPGSRPLSLMPTEYYQKGATEYRRKLAAELEADVQVAWTGVGVVPRTITGRELAGTREVLGHPLVTLDNYPVNDYAQDRIFLGPYTGREPAVATGSAALIATAMEQPAASRIPLFTSGDYAWNPKDYRPMESWQAAMDTLAGEDPETREAVRALARNTASSVLGADESAYLRPLLAKFWATRADAARAAGRPGTEAADAAARAAKELRAAFSVMRATPERLDGGGSGLGEEVRPWSEQLARFGHAGELAVDLLAAQARGDGTAAWHAERALRAVRAETSRNKVTVGDGVLGPFLDQVEKTADSWHGTVGGDGEKVADTGSAYTVALPRVRPLAGVTVRTDPGVSGLVEARVPGKGWQPVTRLEPGGWTDVESRGLRADALRVTGPEAERVDRLVPWYEDGAEAALRLGRGEADAEIGGGTSEVTARLTAHRPGTVRGALKAKTPKGIQVSAPGESVLPRGTEVRIPVSVRVADGVRPGSYEVPVEFGGRSATLTVRAFPPTDDRDLVRSGKATSSADETEDFPARAAADGDPESRWSSPAEDNAWWQTELPEPARVGRVELHWQDAYAAAYRVQVSEDGRIWRTAATVKDGKGGRERVGLDAKNVRFLRVQGDKRATEYGYSLFSVEAYAVTEKEKSKDKGKGDGKAEEKPGRD
>NZ_CP014485.1|WP_003948082.1|5118976_5119327_+|hypothetical-protein
MAASAHLLLSALSKRPELHDLPAIPSPTTLAGRPDDPFDPDTVDYSLVSHPDSGLEGSCAYGLSEPPLTSEPPLADAAPLTSEPPLPDTAPLTSEPAAAAAVVAEDALLGAVSSGG
>NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase
MALSRLAELHGVATSYSPSPDRTVPAAESAVVAALAALGVDASSPEAIRAALEKAEAGQAARLLPPTVVLRSAAPSADPRTAPELAALPPGTRVRLTRDPDPVPARPAPAGGRDAGEAVRRAAPVGEAPPPAWNWTVPLVPAATAPPPPAGSALPPAADVLWAVPFGVHRIEATTPDGRTATSHLVIAPDHIRGPESRAWGLLVQLYSLLSHRSWGMGDLGDLAELATWAGRVHGAGFVQVNPLHAAVPGTPTDPSPYRPSSRRFPDPVHLRVEAIPEYTALSADVRPHLDGLLRRAAELRGRVLSGEALIDRDAVWELKREALERLCAVPLPPGRQAAYEDFTAAHGQALTDHATWAALTERHGPHWSEWPAPLTDPRSRQTAAARTELAARVDFHRRLAWYTDTQLAEAQRAAREAGMAVGLVHDLAVGVHPDGSDAWSQQDVFAAGMSVGAPPDAFNALGQDWGLPPWRPDRLAESGYAPYRGLLRSLLRNAGALRIDHVMGLFRLWWVPVGAPPTDGTYVHYDAEAMLAVLALEAHRADAVVIGEDLGTVEPGVRETLQRHGVLGTSVLWFERDWDGTGLPLPAEAWRASCVATATTHDLPSTASRLTGDHVRLRHRLGLLTRPLAEEEAEEAAATATWLTVLDGLGLMGAAPGGHLPGAAPDEEAAVLAVHRFLLRTPARMIGVWLPDGTGDRRPQNLPGTWDQYPNWRLPVADAQGHPVTLEQLTASPRVARLLRTVATEDQTPAPMVRTAPPDARPV
>NZ_CP014485.1|WP_010637942.1|5121676_5121874_+|hypothetical-protein
MVAGTTLTTLLMTSPALALTRDDGDDPGPGLSVVETLGLYVALPIVLFLVIAGLVMVMDKSGKRS
>NZ_CP014485.1|WP_008414245.1|5123183_5124095_+|LysR-family-transcriptional-regulator
MAPPAPEWDLRKLRILRALHQHGTVTATAEALLMAPSAVSQQLSNFARQLGVPLLEAHGRRVRLTDAAHLVLHHADEVFAQLERADADLAALVRGDAGQVRIGAFSTAVAALVVPLVTRLREEAPGLELRVREAEAGEAYDLLAAGEVDLALSLAAHAPTVRDPRFTRVPLLADPLDVALPSAHPLAGAPDLRLADLAADPWIYGADGPWSDITRAACEAAGFRPEQAHTATGWPAILALVGAELGVALVPRMVSAEYTPGSVVVRPLEADRPRRHVIAAVRRGAEQGGGPVARVLAALRAGA
>NZ_CP014485.1|WP_030308893.1|5124167_5124557_+|hypothetical-protein
MSEHDQGRGRWGDAGGLDGAITGSPRFSVTGGGTRLRVEYRVEGRGVVELTYAPKGEEGEEEISVDQPRLPWRQEVTMRGPVAIPVLSATLDEDGGRADLVVTVDGRERARVTVSGASATGVCVADPGV
>NZ_CP014485.1|WP_061404916.1|5124609_5127627_-|DNRLRE-domain-containing-protein
MPVMKRPGAPRRGRLAIPAAVAALACLITAAPAQAAPPTAPPPVTGGELTEESRAVARAEDSGTPVEVASARTETGEVHAMPDGTLRLTQHAAPVRTRHDGVWKDIDTTLSARDGRVAPRSAAGDVNFSGGGDGPLAVLTDQGRSVELSWPKTLPAPVLQGNTATYRNVLDGVDLAVTAQVDGFSHVLVVHSAEAAADPALKEISYGLKGEGVTVERDTESNTLRALNPAGQELFATATPRMWDSGDAPARRSQGARTADTLSPVDPLAPDVRSAEVGMETSGTTLTLTPDQELLRGEETSYPVYIDPNFSGSKLAWTIAYDRHKNSSFWNGTNWTGSYANEARVGYESDTKGTSRAFFRLNSKELAGATVLSAQFQITNTYSWSCQARNVELWLTGGISASTTWNKQPSWATHLQTKSFAHGYTGCGAKSVDFNATEAAKRSAANGWANITLGLRASSESDTYTWKRFNSNPKIIVSYNRAPNTALAMETRPSTANDTACAVAPYVFVGNTDVTLRARVSDPDGDKVTARFHLWPTGKHPNDAADGVFVVNVDKTNITSGGWAEHTVSKDTLKKYEGFGSGGRFSWKVQARDAHSASDWLPTQGAPGCQFGFDSARPSALPQVSSPEFPGSGDGSVGAPARTPGSFTFTSGGVSDVVSYTYGLNVSPPTTKAEPATAGGPVTVKLTPGYAGPHTLYVFSTDRAGNRSDTQAYSFYADSPGTPDKPGDANGDGFPDLYSLDASGGLRLHPGSGGGGTVGTASALPALGLKDALVTRRGDWTADSFEDLVARHADGTLWLYPADGTGRVADLTRQQVRQFTRPGDEGHIDPATFRQLVSLGDLGQPDQAASPDFLAVIGDALWYLPGFGGGYLDEGYPLADSGWAGRTLVPTGDLDDDGHPDLLVRDTADGKLWLYRGRAGADGSTDPLSLADDTRRTAYGTGFTPAAHPLLAAPGDADGDGVGDLWTTAPSAQGGALLFHRGGTSAPGTPVTVQNGTWGQVRSLT
>NZ_CP014485.1|WP_078842902.1|5134858_5135686_+|hypothetical-protein
MRSPKRGPVAAPWLLFYSRYAGFMDMNGDKLNPGAIIDLTNWAELENADGSAFPVTPAKLHDLTSGDFFKVTSSLSHLYHALLNDGVVYSATAPAFRYVAALLGDRESRAALTPSWDGDKFPLRGKLLSWLADVAFDVSIEHEQRIREWGGYSPTEPFPDFLNIRSIYPEAFPSVASYFDDLDPRVVEAALVAAVRFLESPALAVHRGRLTFLLENVLAQSSSERHRSLASEALASWEQGRVLMEPFTDPHPSEEHGKDHRHSHGKRGSVDEPPF
>NZ_CP014485.1|WP_061404917.1|5135887_5136367_+|hypothetical-protein
MVEAECMTDGSSYGSRPEYLPDFMNDPHDDDGRQVVKLDLAENRVLAAATLSRFPAAAGDVIDFESISFEDRLWWDDEEHWARMAADLLLSHVQRGERIAVIWGNYLMPVVTMPADVAVRRARDILDAGPHFWIHPLGGSVLIECLMDGQVTVATIPSS

Crispr_ID: NZ_CP014485_31

• CRISPR_ID: NZ_CP014485_31
• CRISPR_location: 5132918-5133032
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: Cas9_archaeal

Consensus repeat of NZ_CP014485_31

Consensus_repeat	Method
CCCCGACGGCTCCACCACGCTCCAC	PILER-CR

spacers of NZ_CP014485_31

>31.1|5132943|26|NZ_CP014485|PILER-CR
CTGGGCGAGACCGAGCTGACCGCCAA
>31.2|5132994|21|NZ_CP014485|PILER-CR
CACCGAACGCTTCTACTCCCA

CRISPR arrays and Neighbor proteins around NZ_CP014485_31

CRISPR arrays

The CRISPR arrays of NZ_CP014485_31

>merge|NZ_CP014485|31|5132918-5133032|PILER-CR
CCCCGACGGCTCCACCACGCTCTACCTGGGCGAGACCGAGCTGACCGCCAAGCCCGACGGCACCACCACCACCGAACGCTTCTACTCCCACCCCGACGGCTCCACCACGGTCCGC

>NZ_CP014485|31|10|5132918-5133032|PILER-CR
CCCCGACGGCTCCACCACGCTCTAC	CTGGGCGAGACCGAGCTGACCGCCAA
GCCCGACGGCACCACCACCACCGAA	CGCTTCTACTCCCACCCCGAC
GGCTCCACCACGGTCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061404918.1|5138606_5141183_-|aminopeptidase-N	unknown	unknown	gnl|CDD|274121
NZ_CP014485.1|WP_030771552.1|5147801_5148221_+|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|366659
NZ_CP014485.1|WP_003948082.1|5118976_5119327_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	Cas9_archaeal	cas9_archaeal	gnl|CDD|224321
NZ_CP014485.1|WP_061404921.1|5148306_5150892_-|aminopeptidase-N	unknown	unknown	gnl|CDD|274121
NZ_CP014485.1|WP_061404919.1|5141332_5142361_-|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|237845
NZ_CP014485.1|WP_003948070.1|5137358_5138519_+|allantoicase	unknown	unknown	gnl|CDD|237319
NZ_CP014485.1|WP_008414245.1|5123183_5124095_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NZ_CP014485.1|WP_078842902.1|5134858_5135686_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003948067.1|5142697_5146018_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173796
NZ_CP014485.1|WP_010637942.1|5121676_5121874_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NZ_CP014485.1|WP_061404917.1|5135887_5136367_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein	unknown	unknown	gnl|CDD|369423
NZ_CP014485.1|WP_037842592.1|5136784_5137249_+|SUKH-4-family-immunity-protein	unknown	unknown	gnl|CDD|373067
NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase	unknown	unknown	gnl|CDD|273828
NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase	unknown	unknown	gnl|CDD|376788
NZ_CP014485.1|WP_061404920.1|5146459_5147656_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP014485.1|WP_030308893.1|5124167_5124557_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404916.1|5124609_5127627_-|DNRLRE-domain-containing-protein	unknown	unknown	gnl|CDD|379232

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	Cas9_archaeal	cas9_archaeal	2.6e-11	37.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_030771552.1|5147801_5148221_+|peptidoglycan-binding-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	5.98254e-10
NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease	gnl|CDD|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	4.21562e-21
NZ_CP014485.1|WP_061404921.1|5148306_5150892_-|aminopeptidase-N	gnl|CDD|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NZ_CP014485.1|WP_061404919.1|5141332_5142361_-|aspartate-semialdehyde-dehydrogenase	gnl|CDD|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NZ_CP014485.1|WP_003948070.1|5137358_5138519_+|allantoicase	gnl|CDD|237319	PRK13257, PRK13257, allantoicase; Provisional.	1.10439e-166
NZ_CP014485.1|WP_008414245.1|5123183_5124095_+|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.29595e-45
NZ_CP014485.1|WP_003948067.1|5142697_5146018_-|S8-family-serine-peptidase	gnl|CDD|173796	cd04857, Peptidases_S8_Tripeptidyl_Aminopeptidase_II, Peptidase S8 family domain in Tripeptidyl aminopeptidases_II. Tripeptidyl aminopeptidases II are member of the peptidase S8 or Subtilase family. Subtilases, or subtilisin-like serine proteases, have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure (an example of convergent evolution). Tripeptidyl aminopeptidase II removes tripeptides from the free N terminus of oligopeptides as well as having endoproteolytic activity. Some tripeptidyl aminopeptidases have been shown to cleave tripeptides and small peptides, e.g. angiotensin II and glucagon, while others are believed to be involved in MHC I processing.	1.14446e-63
NZ_CP014485.1|WP_061404920.1|5146459_5147656_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.89572e-58
NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	3.10217e-38
NZ_CP014485.1|WP_061404918.1|5138606_5141183_-|aminopeptidase-N	gnl|CDD|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein	gnl|CDD|369423	pfam07555, NAGidase, beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.	3.27285e-138
NZ_CP014485.1|WP_037842592.1|5136784_5137249_+|SUKH-4-family-immunity-protein	gnl|CDD|373067	pfam14435, SUKH-4, SUKH-4 immunity protein. This family belongs to the SUKH superfamily and functions as immunity proteins in bacterial toxin systems.	1.04108e-06
NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase	gnl|CDD|273828	TIGR01840, poly3-hydroxybutyrate_depolymerase_A_precursor, esterase, PHB depolymerase family. This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation].	6.51534e-74
NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase	gnl|CDD|376788	pfam02446, Glyco_hydro_77, 4-alpha-glucanotransferase. These enzymes EC:2.4.1.25 transfer a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.	2.45652e-161
NZ_CP014485.1|WP_061404916.1|5124609_5127627_-|DNRLRE-domain-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	0.000167981

Protein sequences

>NZ_CP014485.1|WP_061404916.1|5124609_5127627_-|DNRLRE-domain-containing-protein
MPVMKRPGAPRRGRLAIPAAVAALACLITAAPAQAAPPTAPPPVTGGELTEESRAVARAEDSGTPVEVASARTETGEVHAMPDGTLRLTQHAAPVRTRHDGVWKDIDTTLSARDGRVAPRSAAGDVNFSGGGDGPLAVLTDQGRSVELSWPKTLPAPVLQGNTATYRNVLDGVDLAVTAQVDGFSHVLVVHSAEAAADPALKEISYGLKGEGVTVERDTESNTLRALNPAGQELFATATPRMWDSGDAPARRSQGARTADTLSPVDPLAPDVRSAEVGMETSGTTLTLTPDQELLRGEETSYPVYIDPNFSGSKLAWTIAYDRHKNSSFWNGTNWTGSYANEARVGYESDTKGTSRAFFRLNSKELAGATVLSAQFQITNTYSWSCQARNVELWLTGGISASTTWNKQPSWATHLQTKSFAHGYTGCGAKSVDFNATEAAKRSAANGWANITLGLRASSESDTYTWKRFNSNPKIIVSYNRAPNTALAMETRPSTANDTACAVAPYVFVGNTDVTLRARVSDPDGDKVTARFHLWPTGKHPNDAADGVFVVNVDKTNITSGGWAEHTVSKDTLKKYEGFGSGGRFSWKVQARDAHSASDWLPTQGAPGCQFGFDSARPSALPQVSSPEFPGSGDGSVGAPARTPGSFTFTSGGVSDVVSYTYGLNVSPPTTKAEPATAGGPVTVKLTPGYAGPHTLYVFSTDRAGNRSDTQAYSFYADSPGTPDKPGDANGDGFPDLYSLDASGGLRLHPGSGGGGTVGTASALPALGLKDALVTRRGDWTADSFEDLVARHADGTLWLYPADGTGRVADLTRQQVRQFTRPGDEGHIDPATFRQLVSLGDLGQPDQAASPDFLAVIGDALWYLPGFGGGYLDEGYPLADSGWAGRTLVPTGDLDDDGHPDLLVRDTADGKLWLYRGRAGADGSTDPLSLADDTRRTAYGTGFTPAAHPLLAAPGDADGDGVGDLWTTAPSAQGGALLFHRGGTSAPGTPVTVQNGTWGQVRSLT
>NZ_CP014485.1|WP_030308893.1|5124167_5124557_+|hypothetical-protein
MSEHDQGRGRWGDAGGLDGAITGSPRFSVTGGGTRLRVEYRVEGRGVVELTYAPKGEEGEEEISVDQPRLPWRQEVTMRGPVAIPVLSATLDEDGGRADLVVTVDGRERARVTVSGASATGVCVADPGV
>NZ_CP014485.1|WP_008414245.1|5123183_5124095_+|LysR-family-transcriptional-regulator
MAPPAPEWDLRKLRILRALHQHGTVTATAEALLMAPSAVSQQLSNFARQLGVPLLEAHGRRVRLTDAAHLVLHHADEVFAQLERADADLAALVRGDAGQVRIGAFSTAVAALVVPLVTRLREEAPGLELRVREAEAGEAYDLLAAGEVDLALSLAAHAPTVRDPRFTRVPLLADPLDVALPSAHPLAGAPDLRLADLAADPWIYGADGPWSDITRAACEAAGFRPEQAHTATGWPAILALVGAELGVALVPRMVSAEYTPGSVVVRPLEADRPRRHVIAAVRRGAEQGGGPVARVLAALRAGA
>NZ_CP014485.1|WP_010637942.1|5121676_5121874_+|hypothetical-protein
MVAGTTLTTLLMTSPALALTRDDGDDPGPGLSVVETLGLYVALPIVLFLVIAGLVMVMDKSGKRS
>NZ_CP014485.1|WP_015507887.1|5119328_5121623_+|4-alpha-glucanotransferase
MALSRLAELHGVATSYSPSPDRTVPAAESAVVAALAALGVDASSPEAIRAALEKAEAGQAARLLPPTVVLRSAAPSADPRTAPELAALPPGTRVRLTRDPDPVPARPAPAGGRDAGEAVRRAAPVGEAPPPAWNWTVPLVPAATAPPPPAGSALPPAADVLWAVPFGVHRIEATTPDGRTATSHLVIAPDHIRGPESRAWGLLVQLYSLLSHRSWGMGDLGDLAELATWAGRVHGAGFVQVNPLHAAVPGTPTDPSPYRPSSRRFPDPVHLRVEAIPEYTALSADVRPHLDGLLRRAAELRGRVLSGEALIDRDAVWELKREALERLCAVPLPPGRQAAYEDFTAAHGQALTDHATWAALTERHGPHWSEWPAPLTDPRSRQTAAARTELAARVDFHRRLAWYTDTQLAEAQRAAREAGMAVGLVHDLAVGVHPDGSDAWSQQDVFAAGMSVGAPPDAFNALGQDWGLPPWRPDRLAESGYAPYRGLLRSLLRNAGALRIDHVMGLFRLWWVPVGAPPTDGTYVHYDAEAMLAVLALEAHRADAVVIGEDLGTVEPGVRETLQRHGVLGTSVLWFERDWDGTGLPLPAEAWRASCVATATTHDLPSTASRLTGDHVRLRHRLGLLTRPLAEEEAEEAAATATWLTVLDGLGLMGAAPGGHLPGAAPDEEAAVLAVHRFLLRTPARMIGVWLPDGTGDRRPQNLPGTWDQYPNWRLPVADAQGHPVTLEQLTASPRVARLLRTVATEDQTPAPMVRTAPPDARPV
>NZ_CP014485.1|WP_003948082.1|5118976_5119327_+|hypothetical-protein
MAASAHLLLSALSKRPELHDLPAIPSPTTLAGRPDDPFDPDTVDYSLVSHPDSGLEGSCAYGLSEPPLTSEPPLADAAPLTSEPPLPDTAPLTSEPAAAAAVVAEDALLGAVSSGG
>NZ_CP014485.1|WP_061404915.1|5115565_5118625_-|beta-N-acetylglucosaminidase-domain-containing-protein
MQLRRSRTAAALAVAVIAGTLGGAPTALAAPPAPDPATAADEAPDDAKGETAGLPSVWPRPQSLRAADGKVALGSRVVLVAPLGTDPYALKALREVLREAGVRDVDEVSAEGDVPAGATPVVRVGGESAARPGAGGAGLEKTLRALGASARGDLPQGGYRLAAGQADGRPTVAMAGVGEDGLFHAVQTLRQLVRDGVVPGVVVRDWPGTPVRGLSEGFYGTPWTTEQRLGQLDFLGRTKQNHYLYAPGDDLFRQARWREPYPAGQRAAFRALAERARENHVTLAWAVAPGQAMCLASEDDVKALNRKIDAMWALGARAFQLQFQDVSYSEWHCGEDEAEFGSGPAAAARAQARVANAVAAHLAERHPGSRPLSLMPTEYYQKGATEYRRKLAAELEADVQVAWTGVGVVPRTITGRELAGTREVLGHPLVTLDNYPVNDYAQDRIFLGPYTGREPAVATGSAALIATAMEQPAASRIPLFTSGDYAWNPKDYRPMESWQAAMDTLAGEDPETREAVRALARNTASSVLGADESAYLRPLLAKFWATRADAARAAGRPGTEAADAAARAAKELRAAFSVMRATPERLDGGGSGLGEEVRPWSEQLARFGHAGELAVDLLAAQARGDGTAAWHAERALRAVRAETSRNKVTVGDGVLGPFLDQVEKTADSWHGTVGGDGEKVADTGSAYTVALPRVRPLAGVTVRTDPGVSGLVEARVPGKGWQPVTRLEPGGWTDVESRGLRADALRVTGPEAERVDRLVPWYEDGAEAALRLGRGEADAEIGGGTSEVTARLTAHRPGTVRGALKAKTPKGIQVSAPGESVLPRGTEVRIPVSVRVADGVRPGSYEVPVEFGGRSATLTVRAFPPTDDRDLVRSGKATSSADETEDFPARAAADGDPESRWSSPAEDNAWWQTELPEPARVGRVELHWQDAYAAAYRVQVSEDGRIWRTAATVKDGKGGRERVGLDAKNVRFLRVQGDKRATEYGYSLFSVEAYAVTEKEKSKDKGKGDGKAEEKPGRD
>NZ_CP014485.1|WP_061405521.1|5114059_5115550_+|PHB-depolymerase-family-esterase
MVTLAGVAGPESVTAPARAASLTEVTGFGSNPGNLRMFRYVPDGLPAGRPLVVAMHGCTQSAGGFDDETGWTKWADQWGFALVLPQQQSANNLNSCFNWFEAGDIRRDAGEALSIKQMTDRMKADVGSDPARVHATGLSAGAAMTNVMLAAYPDVFASGAPVAGLPYACATSVVAAYSCMNPGSNLTPAAWAAKVRDAYPGYAGPWPAVSVWQGTTDTTVVPANLTETVEQWTAVHGTDTTPDATGTVGGYPHAVYRDGDGRDVVETYTITGMGHGQPVDPGSGAEQCGTAGAYILDVNICAAYHIGRFWGLAEDGGGTDPGTPAQRAVIPSTAADDGYVKASASGTGAAVGALEGTMGAAVGRGTDGQHNRTLLSFDTSAVPDDATITRAYVTVSRASGSGDPWAGGNRLLIDVRSGCFGASCATAADDWAAPATASGAAELARFTSGRADSTAFTEVNRTGPTQLRLRLADAPASTAYLFLRTGAEAKLTVEWE
>NZ_CP014485.1|WP_003948086.1|5113020_5113599_+|HNH-endonuclease
MPHVLVLNASYEPLGVVPLRRALVLVLESKAVCLEESGAFLHSESRTVPAPSVVRLKRFVKVPYRGPVPLTRRALFARDGGRCVYCGGVATSVDHVIPRSRGGLHVWDNVVASCRRCNHVKADRHLMELGWRLRNKPAPPTGLAWRIIGTGHRDPRWLPYLQPFGGDDALARIENVGAGGEAVAVRPARAGA
>NZ_CP014485.1|WP_037842600.1|5111563_5112625_-|mechanosensitive-ion-channel-family-protein
MFPSAPAAGREDTVTLEEAQERATDAAGWVSENWSTWLETGLRILLIIVVAAALRMVIRKTITNLIDRMNRTASAVDGTALGGLLVNAERRRQRSQAIGSVLRSVASFLIVGTAALMILDTFKINLAPLLASAGVAGVAIGFGARNLVTDFLSGVFMILEDQYGVGDTIDAGVATGEVVEVGLRVTKLRGPNGAVWYVRNGEVKRIGNLSQGWSTAAVEVTVRSDEDLDKVRDTLTEVGAQIAKDEPWNERLWGPVEVLGLDSVLLDSMVVGVSAKTMPGQDVAVERELRWRIKKAFDAAGISIVGGPAELAEEDAADPSAGMAAPSAYASATSPQSLAASPIPPASGPRLGK
>NZ_CP014485.1|WP_078842902.1|5134858_5135686_+|hypothetical-protein
MRSPKRGPVAAPWLLFYSRYAGFMDMNGDKLNPGAIIDLTNWAELENADGSAFPVTPAKLHDLTSGDFFKVTSSLSHLYHALLNDGVVYSATAPAFRYVAALLGDRESRAALTPSWDGDKFPLRGKLLSWLADVAFDVSIEHEQRIREWGGYSPTEPFPDFLNIRSIYPEAFPSVASYFDDLDPRVVEAALVAAVRFLESPALAVHRGRLTFLLENVLAQSSSERHRSLASEALASWEQGRVLMEPFTDPHPSEEHGKDHRHSHGKRGSVDEPPF
>NZ_CP014485.1|WP_061404917.1|5135887_5136367_+|hypothetical-protein
MVEAECMTDGSSYGSRPEYLPDFMNDPHDDDGRQVVKLDLAENRVLAAATLSRFPAAAGDVIDFESISFEDRLWWDDEEHWARMAADLLLSHVQRGERIAVIWGNYLMPVVTMPADVAVRRARDILDAGPHFWIHPLGGSVLIECLMDGQVTVATIPSS
>NZ_CP014485.1|WP_037842592.1|5136784_5137249_+|SUKH-4-family-immunity-protein
MRSAGLRAEDRELLSVRGLPDDSNRMFVRDPRRELEVRELADVGAAAFLGDFEDGVNSYWLSVSAGSVWMKKGYGLDEGDVRLANTTLRAFQEMLRIWEEFVFSGVHEESDAYEPLVERTLAKAEETDPVVFEDEESWWARVFEEVELGSLAPE
>NZ_CP014485.1|WP_003948070.1|5137358_5138519_+|allantoicase
MTTHPATPDSQDAHADDPHANDAAPYPGGDPYGDYRTHGVDFSATDLVDLADRRLGAGVIAANDEFFAQRENLLVRERAVFDPEHFGHKGKVMDGWETRRRRGAGPETPFPAPEEHDWALIRLGAPGVVKGVVVDTAHFRGNYPQRVSLQATAVEGNPGPEELLASDVKWEELLPPTPVLGHAANGFAFDVERRFTHLRLCQHPDGGIARLRVYGEVVPDPEWLGLLGTVDLAAVLNGGVYEDASDRFYSSPTQIIQPGTSRKMDDGWENRRRRVRDTNDWVRFRLAAQGVIRAVEIDTAYLKGNSAGWVALSARDGEDGEWYEILPRTRLQPDTPHRFRLATPATATHVRLDAFPDGGVARMRLHGELTEAGAAALADRYRRLAG
>NZ_CP014485.1|WP_061404918.1|5138606_5141183_-|aminopeptidase-N
MPGTNLTREEAQERARLLTVDAYEIELDLSGAQDGGTFRSVTSVRFDSAEAGASTFVDLIAPAVHEVVLNGTALDVAAVFRDSRIALDGLLQGRNELRVVADCAYTNTGEGLHRFVDPVDEQAYLYTQFEVPDSRRVFAVFEQPDLKGTFTFTVTAPTGWTVISNSPTPEPEGDVWRFEPTPRISSYITALIAGPYHAVHSVYEKDGRRVPLGIYCRPSLAEHLDAEHIFDVTRQGFDWFQEKFDYAYPFAKYDQLFVPEFNAGAMENAGAVTIRDQYVFRSKVTDAAYERRAETILHELAHMWFGDLVTMEWWNDLWLNESFATFTSVACQAAAPGSRWPHSWTTFANAEKTWAYRQDQLPSTHPIMAEINDLDDVLVNFDGITYAKGASVLKQLVAYVGEDAFFAGVQAYFKQHAFGNTKLTDLLGALEKTSGRDLTTWAQKWLQTAGINVLRPEITTDADGTVTSFAVRQTAPALPAGAKGTAVLRPHRIAIGSYDLDDAGRLVRTGRIELDVDGELTEVPELVGTGRPAVFLLNDDDLSYAKVRLDEDSLAVVTAHLGDFAESLPRALSWASAWDMTRDGELATRDYLDLVISGIPKESDIGVVQSLQRQVHMAIEQYADPAWRPEGLARWTEFALEQLRAAAPGSDHQLAWARAFADTARTDTQLDLLEALLDGGETIEGLAVDTELRWALLHRLAATGRADEGAVDAELARDRTAAGERHAASARSARPTEEAKATAWASVVESDKLANAVQEAVIGGFVQYDQRELLAPYTAKYFAAVKDVAAGRSHEMVQQIVVGLYPALQISQETLDATDAWIAANDPTPGLRRMITECRAGVERALRAREADAAAGRA
>NZ_CP014485.1|WP_061404919.1|5141332_5142361_-|aspartate-semialdehyde-dehydrogenase
MRVGIVGATGQVGTVMRRILAERNFPVSELRLFASARSAGSAIEWQGSEVTVEDASTADYSGLDIVLFSAGGATSRALAEKVAAQGPVVIDNSSAWRRDPEVPLVVSEVNPHAIADRPKGIIANPNCTTMAAMPVLRPLHDEAGLEALVVATYQAVSGSGLAGVAELHGQTQKVVAEADQLTHDGAAVDFPEPGVYARPIAFNVLPLAGSVVDDGSFETDEEQKLRNESRKILEIPELKVSGTCVRVPVFSGHSLQINARFARPLGVERATELLKGAEGVELSEIPTPLQAAGQDPSYVGRIRVDETVENGLSLFVSNDNLRKGAALNAVQIAELVAAELKG
>NZ_CP014485.1|WP_003948067.1|5142697_5146018_-|S8-family-serine-peptidase
MTSESPQAPISGARRAARVAVAAGLVAALCAGAPLPMAFAADEPATAPTVKSAADKLGSADAERLAEAKADGDKHVTMMIATQPGRTAEVAGKLKAVKGGSVGKTHDKLGYVRATVPTGQADAAIKAAAKLSAVHGIDLNQEIQLDDPTPSGDRAKGVKSAATDSDDFYGAPNAKTPAKNPFNPSFETGAVEFVEKNPKADGRGITIGILDSGIDLGHPALQKTTTGERKITDWVTATDPIVDGDQTWRPMVDAVSGPSFTYKGRTYKAPAGSYQVSVFAEAASKGGDADGDLNRDGDTTDTWGVLYDAKNGTVRVDLNDNGDFTDDEVLRPYKDKFQVGYFGKDDPKTDVVEQIPFVVELRKGVPMDPYGGSWVGKKADFVNIGIIEGSHGTHVAGITAANSLFGGKMNGAAPGAKLVSSRACTWSGGCTSVALTEGMIDLAANRGVDIINMSIGGLPALNDGNNARAELYTRIIDAFGVQLVISAGNSGPGANTIGDPSLADKVISVGATISKETWLANYGSEVRKPYAMMPFSSRGPREDGGFTPTLSAPGAAINTTQTWFPGGPTLEAGYDLPAGYSMLQGTSMASPQAAGASALLLSKAKQQGIDLTPAKLRSALTSTATQIDGVQAYEQGAGLINIVDAWKQINKQDGDTHEYTVRAPVDTAIDELLKDPGHGTGVYDREGGLKVGKKRLYDITVTRTTGPKKAVSHKLALVNNHDETFKLVGGKKVDLKLNKPVTLTVSAKAATKGLHSAILTVDDPSTQGTDQQIMTTVVAADELAKPSFTVKKSGEVDRNETRSYFVEVPEGAKSLEVSLGGLFGKSQVRFISIHPYGVPVDSTSTPNCYNNYNNGNGCRPDLRSYADPAPGVWEIEVEARRTSPLLRNPYQLEVSLLGVAFDPAVQTVPEAKVGTPAPVEWKITNENAALEGKLKGGPLGSSLSKRPEIKNGEAQTSEITVGEGVERLDVAIGNVSDVAADLDLTLYDEQGNQVAQTADGDSEEALSVAKPKPGTYTVEVYAYSVPSGSTAYDYRDVYFSAALGEVKVDTAKTVKLATGASAKIAAEVLVAAPAPEGRKFFGQVQVLNAKGTAAGSGSVEIGKVTE
>NZ_CP014485.1|WP_061404920.1|5146459_5147656_+|serine-hydrolase
MAAPTTPPRPARRHRRPARLAAALAPATALATLTPAPLAAASTTRGHEGTQRVLDTAVADGVPGALARARDRHGVWNGTAGTADLDTGRARGADDRFRIGSVTKTFVATVLLQLQGERRIDLDDTVDQHLPGLVDGHGHDGTAITLRQLLNHTSGISNYTADPEFRRRAFGEEFLDHRYDTWKPGQLVAVAMRHAPDFAPGTSWNYSNTNYILAGMVIEKVTGHGWEKEVERRILRPLGLRATSAPRTDPHLPRPAGRAYSFLGDPDREHPYDVTELNPSQAGAAGAMISTTADLDRFQRALLGGRLLPPAQLRQMTTTVEVHPSAPHVRYGLGLMRQTLSCGIRIWGHDGGIHGSATLAFTTRDTRHSYQANLNGEWSPSDPADAVALTEAEFCREG
>NZ_CP014485.1|WP_030771552.1|5147801_5148221_+|peptidoglycan-binding-protein
MGDPVTHRRRAFALLTASAALLAGAVTAAPAATAAPAAAAAPKKCYTQSTIGLTCHHHYGAKWAEYGSTGAHVKEIQALINGTTTYYGTHGKALAVDGIYGAGTRSAVRWFQQKYIGASAVDGIVGPRTWDALRGFGRK
>NZ_CP014485.1|WP_061404921.1|5148306_5150892_-|aminopeptidase-N
MPGENLTRDEARERAALVAVESYDVALDLRSALGEVTGDGPRTFRSVTTIRFAGLRPGAATFVDLIAPSVSAVTLNGRALDVAEVFDGTRIALEGLEAENTLVVDAQCAYSRTGEGMHRFVDPQDGEVYLYTQYEPADSRRVYANFEQPDLKGRYRFSVTAPEGWGVWSNGAGERDADGVWRFAETEPISTYITCVVAGPYHYVTDDYRRTLPDGSELRIPLGAMCRKGLAPHFDADDIFLVTKQGLDFFHDHFGYPYPFGKYDQAFVPEYNLGAMENPGMVTFREEYIYRGKVTAASYERRATTILHEMAHMWFGDLVTMKWWDDLWLKESFADFMGSFALVEATRFTNGWTTFANNRKAWAYRADQLPSTHPITADIRDLQDAKLNFDGITYAKGASVLKQLVAYVGRDAFLEGARRYFQRHAFGNTTLADLLAVLEETSGRDLAGWSKAWLQTAGVNALTPELTLDAENRITELAVAQEAAASHPELRPHRVAVGLYRLDGVEGALVRYARAELDVTGPRTVVTELAGAEAPDLVLVNDDDLTYCKVRFDENSLATLRSRLGDIADPLARALCWSALWNMTRDGLMPARNFLSLVLEHAGRESDIGVLQMLHAWARTALVHYVVPARRDEAGRALAQGALAELRAAEPGGPAQLTWARFFASVASDEADLQLLGALLDGPARIDGLDMDQELRWTFLEPLAAYGVVDEERIAAELARDDTASGRRHQVRCLAARPSEAVKAQAWAQVVESDALSNALVEATIAGFAQPSQRELTAPYAAKYFEAIGRVWEERSIQIGVLVVRGLFPSLQDGPEPLAAADAWLGEHTDAPPALRRLVLESRDDLARAHRAQVTDAGTGA

Crispr_ID: NZ_CP014485_32

• CRISPR_ID: NZ_CP014485_32
• CRISPR_location: 5158783-5158869
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_32

Consensus_repeat	Method
TAGCCCGGCCGGCGTTTGAGGCC	CRISPRCasFinder

spacers of NZ_CP014485_32

>32.1|5158806|41|NZ_CP014485|CRISPRCasFinder
AGTCTTTGACCGGCACGGTTGAAACGGAGCCCGGCTACCAC

CRISPR arrays and Neighbor proteins around NZ_CP014485_32

CRISPR arrays

The CRISPR arrays of NZ_CP014485_32

>merge|NZ_CP014485|32|5158783-5158869|CRISPRCasFinder
TAGCCCGGCCGGCGTTTGAGGCCAGTCTTTGACCGGCACGGTTGAAACGGAGCCCGGCTACCACCAGCCCGGCCGGCGTTTGAGGCC

>NZ_CP014485|32|25|5158783-5158869|CRISPRCasFinder
TAGCCCGGCCGGCGTTTGAGGCC	AGTCTTTGACCGGCACGGTTGAAACGGAGCCCGGCTACCAC
CAGCCCGGCCGGCGTTTGAGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_030771552.1|5147801_5148221_+|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|366659
NZ_CP014485.1|WP_061404923.1|5157687_5158281_+|biotin-transporter-BioY	unknown	unknown	gnl|CDD|376871
NZ_CP014485.1|WP_061404921.1|5148306_5150892_-|aminopeptidase-N	unknown	unknown	gnl|CDD|274121
NZ_CP014485.1|WP_061404924.1|5164794_5166006_-|cation:proton-antiporter	unknown	unknown	gnl|CDD|223551
NZ_CP014485.1|WP_003948061.1|5153484_5154123_-|superoxide-dismutase	unknown	unknown	gnl|CDD|223678
NZ_CP014485.1|WP_003948050.1|5168316_5168511_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405522.1|5155915_5157361_-|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NZ_CP014485.1|WP_003948067.1|5142697_5146018_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173796
NZ_CP014485.1|WP_003948049.1|5169153_5170551_+|trigger-factor	unknown	unknown	gnl|CDD|234956
NZ_CP014485.1|WP_061404920.1|5146459_5147656_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP014485.1|WP_015507891.1|5160772_5161264_+|ribose-5-phosphate-isomerase	unknown	unknown	gnl|CDD|235509
NZ_CP014485.1|WP_008411884.1|5171534_5172206_+|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl|CDD|237133
NZ_CP014485.1|WP_003948063.1|5151056_5151701_+|DsbA-family-protein	unknown	unknown	gnl|CDD|376526
NZ_CP014485.1|WP_003948057.1|5158963_5160400_-|amino-acid-permease	unknown	unknown	gnl|CDD|273797
NZ_CP014485.1|WP_008411871.1|5154281_5155730_-|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NZ_CP014485.1|WP_008411881.1|5166340_5167543_-|acyltransferase-family-protein	unknown	unknown	gnl|CDD|226122
NZ_CP014485.1|WP_061404922.1|5151787_5153242_+|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|223154
NZ_CP014485.1|WP_008411883.1|5170849_5171467_+|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl|CDD|178955
NZ_CP014485.1|WP_003948046.1|5172364_5173651_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl|CDD|235422
NZ_CP014485.1|WP_003948054.1|5162087_5163317_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|234945

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_030771552.1|5147801_5148221_+|peptidoglycan-binding-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	5.98254e-10
NZ_CP014485.1|WP_061404923.1|5157687_5158281_+|biotin-transporter-BioY	gnl|CDD|376871	pfam02632, BioY, BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is a component of the BioMNY transport system involved in biotin uptake in prokaryotes.	2.62695e-30
NZ_CP014485.1|WP_061404921.1|5148306_5150892_-|aminopeptidase-N	gnl|CDD|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NZ_CP014485.1|WP_061404924.1|5164794_5166006_-|cation:proton-antiporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.35501e-41
NZ_CP014485.1|WP_003948061.1|5153484_5154123_-|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	5.17808e-80
NZ_CP014485.1|WP_003948049.1|5169153_5170551_+|trigger-factor	gnl|CDD|234956	PRK01490, tig, trigger factor; Provisional.	7.22577e-154
NZ_CP014485.1|WP_061405522.1|5155915_5157361_-|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	2.3165e-159
NZ_CP014485.1|WP_003948067.1|5142697_5146018_-|S8-family-serine-peptidase	gnl|CDD|173796	cd04857, Peptidases_S8_Tripeptidyl_Aminopeptidase_II, Peptidase S8 family domain in Tripeptidyl aminopeptidases_II. Tripeptidyl aminopeptidases II are member of the peptidase S8 or Subtilase family. Subtilases, or subtilisin-like serine proteases, have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure (an example of convergent evolution). Tripeptidyl aminopeptidase II removes tripeptides from the free N terminus of oligopeptides as well as having endoproteolytic activity. Some tripeptidyl aminopeptidases have been shown to cleave tripeptides and small peptides, e.g. angiotensin II and glucagon, while others are believed to be involved in MHC I processing.	1.14446e-63
NZ_CP014485.1|WP_061404920.1|5146459_5147656_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.89572e-58
NZ_CP014485.1|WP_015507891.1|5160772_5161264_+|ribose-5-phosphate-isomerase	gnl|CDD|235509	PRK05571, PRK05571, ribose-5-phosphate isomerase B; Provisional.	5.17155e-85
NZ_CP014485.1|WP_008411884.1|5171534_5172206_+|ATP-dependent-Clp-protease-proteolytic-subunit	gnl|CDD|237133	PRK12553, PRK12553, ATP-dependent Clp protease proteolytic subunit; Reviewed.	2.22318e-122
NZ_CP014485.1|WP_003948063.1|5151056_5151701_+|DsbA-family-protein	gnl|CDD|376526	pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyze one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways. This family also contains members with functions other than HCCA isomerisation, such as Kappa family GSTs, whose similarity to HCCA isomerases was not previously recognized. Some members have been annotated as dioxygenases, dehydrogenases, or putative glycerol-3-phosphate transfer proteins, but are most likely HCCA isomerase enzymes.	2.6397e-08
NZ_CP014485.1|WP_003948057.1|5158963_5160400_-|amino-acid-permease	gnl|CDD|273797	TIGR01773, GABA_permease, gamma-aminobutyrate permease. GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_CP014485.1|WP_008411871.1|5154281_5155730_-|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	6.25042e-155
NZ_CP014485.1|WP_008411881.1|5166340_5167543_-|acyltransferase-family-protein	gnl|CDD|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	3.19877e-32
NZ_CP014485.1|WP_061404922.1|5151787_5153242_+|aspartate-aminotransferase-family-protein	gnl|CDD|223154	COG0076, GadB, Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism].	1.17276e-80
NZ_CP014485.1|WP_008411883.1|5170849_5171467_+|ATP-dependent-Clp-protease-proteolytic-subunit	gnl|CDD|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	8.14405e-121
NZ_CP014485.1|WP_003948046.1|5172364_5173651_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl|CDD|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NZ_CP014485.1|WP_003948054.1|5162087_5163317_-|GNAT-family-N-acetyltransferase	gnl|CDD|234945	PRK01346, PRK01346, enhanced intracellular survival protein Eis.	1.40306e-160

Protein sequences

>NZ_CP014485.1|WP_061404923.1|5157687_5158281_+|biotin-transporter-BioY
MSTAAASTRPGQVLADLLPASTVPRARLRDAALVTGGAALTGLAAQIVLPVPGSPVPVTGQTFAALLVGTALGAGRGFASLALYALVGMAGVPWFAEGTSGASMPSFGYVLGMLLAATVVGALARRGADRSVLRTAGLMVLGSALIYAVGVPYLALSTGMSLTSAVAAGLVPFLIGDALKAALAMGALPLAWRLTRD
>NZ_CP014485.1|WP_061405522.1|5155915_5157361_-|amino-acid-permease
MHDAPAGPGDPGATSATTARDPFDSAKPLGHGLKQRHLTMLGLGGVIGAGLFVGSGAGIAVAGPGIVVSYLIAGTLAMLVMRMLGEMSAAMPSSGSFSVHAERALGRWAGFSVGWLYWFLLVVVLAVEATGAAQIANGWVPSVPQWAWVLVFMLVFTGANLAAVKHFGEFEFWFAALKVGAIVLFLVLGVLAILGLLPETEPVGLAHLSGDDGFLPNGWSGVISGVLAVVFAFGGLEVVTIAAAESDDPARSVARAVRSAVYRILFFYVGSMLVIVTLLPWTAMRPGLSPYVAVLDGIGIPSAGQIMNIVVFVALLSALNANLYGSSRMVFSLAERGEAPRALLKVAPGGVPRRAVLASVAFGFVSVLLNLKWPDSVFLYMLNAVGAVLIFVWALIAVSQLRLRRLIEREAPERLVLRMWGYPWLTWAALVAMAAVFTLMLFDSTARPQLLWSSGAAALVLLVAGVREWRLRRGTGAAATG
>NZ_CP014485.1|WP_008411871.1|5154281_5155730_-|amino-acid-permease
MTRTTLTPGDTPGADQRPGGDQASDTGSALSNGLKQRHLSMIALGGVIGAGLFVGSGAGIAAAGPSIVFAYAASGLLVMLVMRMLGEMSAANPASGSFSVHAERAIGPWAGFTSGWAFWFLLCVAVGLEGIGAAEIMSGWLPGTPEWAWVALFMVIFCGTNLAAVKNFGEFEFWFATLKVVAIVVFLVIGVLAILGVLPGSEAPGTSNLTGEGGFLPNGSEGFIIGLLASVFAYGGLETVTIAAAESERPAEGVAKAVRTAMWRIGVFYVGSMAVIVTLVPWDDPAVAEKGPYVATLDHLGIPGSGQIMNVVVLIALLSAMNANIYGASRMACSLVARGQGPRKLGRVFNGVPRIAVLASSFFGFVCVLLSYWRPDDVFAWLLNMIGAVILVVWFFTAASQLLLRRRTEREAPERLVVRMWLFPGLTWVALAAMAGVFVLMAKEPDTRVQLLSTGSLTVALALAGYLLQRKRAAAPAGVGKG
>NZ_CP014485.1|WP_003948061.1|5153484_5154123_-|superoxide-dismutase
MSVYTLPELPYDYAALEPVINPAIIELHHDKHHAAYVKGANDTLEQLAEARDKDQWGAVTGLEKSLAFNLSGHILHSIYWHNMTGDGGGEPLAEDGVGELADAIRESFGSFAGFKAQLTKAAATTQGSGWGVLAYEPLSGRLIVEQIYDHQGNVGQGSTPILVFDAWEHAFYLQYKNQKVDFIEAMWRVVNWQDVARRYASAKARENVLLAP
>NZ_CP014485.1|WP_061404922.1|5151787_5153242_+|aspartate-aminotransferase-family-protein
MPKPEPPARPDVLKEIAALREADAPTRGGRTFAYVYDPAVEGLDALAADAYRAFADVNALDMTVFPSVARLENDLVARVAAHLGAPGCQGTFTSGGTESILLAVKTARDHARATRGVRAGELVLPATAHAAFHKAAHYLGLTPVTVPVDPETYRADPAATARALTPDTVLVVASAPSYAHGVLDPVAEIAALAAEAGVLCHVDACVGGWLLPFLRRAGREVPDFNLTVPGVTSLSVDLHKYGYADKGASVVLYRDAALRRHQYFAHADWPGYPVVNPTVQGTKSAGLLAQAWAVLRYLTDEDYTALAARVADAETRLLTGLAALDGLRVLGTPAAGLVAVTATGPDGTPDLSTVLHLADEMRARGWYLQPQLAHGALPPNLHLTLTPATADRVDALLADLTTALATARTLPPATPAPDLAALAATLDPDTLTDEEAVAVLTYAGLGPDTGTPDRMAPVLALLAALPTRLKERLLTEYIGSLFQI
>NZ_CP014485.1|WP_003948063.1|5151056_5151701_+|DsbA-family-protein
MTDPQQNTEVTADFWFDPLCPWAWMTSRWMLEVEKVRPVRVRWNVMSLAVLNEDRLDELPEGYRELLTQAWGPVRVVIAAQQLHGAEVAGPLYTALGTRYHNQQQPKDRATLVAALEEVGLPADLADYADKDTYDAELRASHAAGITKVGQDVGTPVIAVPGADGEEVAFFGPVVTPAPKGDQAAALWDGTLLVASVPGFYELKRTRTAEPSFD
>NZ_CP014485.1|WP_061404921.1|5148306_5150892_-|aminopeptidase-N
MPGENLTRDEARERAALVAVESYDVALDLRSALGEVTGDGPRTFRSVTTIRFAGLRPGAATFVDLIAPSVSAVTLNGRALDVAEVFDGTRIALEGLEAENTLVVDAQCAYSRTGEGMHRFVDPQDGEVYLYTQYEPADSRRVYANFEQPDLKGRYRFSVTAPEGWGVWSNGAGERDADGVWRFAETEPISTYITCVVAGPYHYVTDDYRRTLPDGSELRIPLGAMCRKGLAPHFDADDIFLVTKQGLDFFHDHFGYPYPFGKYDQAFVPEYNLGAMENPGMVTFREEYIYRGKVTAASYERRATTILHEMAHMWFGDLVTMKWWDDLWLKESFADFMGSFALVEATRFTNGWTTFANNRKAWAYRADQLPSTHPITADIRDLQDAKLNFDGITYAKGASVLKQLVAYVGRDAFLEGARRYFQRHAFGNTTLADLLAVLEETSGRDLAGWSKAWLQTAGVNALTPELTLDAENRITELAVAQEAAASHPELRPHRVAVGLYRLDGVEGALVRYARAELDVTGPRTVVTELAGAEAPDLVLVNDDDLTYCKVRFDENSLATLRSRLGDIADPLARALCWSALWNMTRDGLMPARNFLSLVLEHAGRESDIGVLQMLHAWARTALVHYVVPARRDEAGRALAQGALAELRAAEPGGPAQLTWARFFASVASDEADLQLLGALLDGPARIDGLDMDQELRWTFLEPLAAYGVVDEERIAAELARDDTASGRRHQVRCLAARPSEAVKAQAWAQVVESDALSNALVEATIAGFAQPSQRELTAPYAAKYFEAIGRVWEERSIQIGVLVVRGLFPSLQDGPEPLAAADAWLGEHTDAPPALRRLVLESRDDLARAHRAQVTDAGTGA
>NZ_CP014485.1|WP_030771552.1|5147801_5148221_+|peptidoglycan-binding-protein
MGDPVTHRRRAFALLTASAALLAGAVTAAPAATAAPAAAAAPKKCYTQSTIGLTCHHHYGAKWAEYGSTGAHVKEIQALINGTTTYYGTHGKALAVDGIYGAGTRSAVRWFQQKYIGASAVDGIVGPRTWDALRGFGRK
>NZ_CP014485.1|WP_061404920.1|5146459_5147656_+|serine-hydrolase
MAAPTTPPRPARRHRRPARLAAALAPATALATLTPAPLAAASTTRGHEGTQRVLDTAVADGVPGALARARDRHGVWNGTAGTADLDTGRARGADDRFRIGSVTKTFVATVLLQLQGERRIDLDDTVDQHLPGLVDGHGHDGTAITLRQLLNHTSGISNYTADPEFRRRAFGEEFLDHRYDTWKPGQLVAVAMRHAPDFAPGTSWNYSNTNYILAGMVIEKVTGHGWEKEVERRILRPLGLRATSAPRTDPHLPRPAGRAYSFLGDPDREHPYDVTELNPSQAGAAGAMISTTADLDRFQRALLGGRLLPPAQLRQMTTTVEVHPSAPHVRYGLGLMRQTLSCGIRIWGHDGGIHGSATLAFTTRDTRHSYQANLNGEWSPSDPADAVALTEAEFCREG
>NZ_CP014485.1|WP_003948067.1|5142697_5146018_-|S8-family-serine-peptidase
MTSESPQAPISGARRAARVAVAAGLVAALCAGAPLPMAFAADEPATAPTVKSAADKLGSADAERLAEAKADGDKHVTMMIATQPGRTAEVAGKLKAVKGGSVGKTHDKLGYVRATVPTGQADAAIKAAAKLSAVHGIDLNQEIQLDDPTPSGDRAKGVKSAATDSDDFYGAPNAKTPAKNPFNPSFETGAVEFVEKNPKADGRGITIGILDSGIDLGHPALQKTTTGERKITDWVTATDPIVDGDQTWRPMVDAVSGPSFTYKGRTYKAPAGSYQVSVFAEAASKGGDADGDLNRDGDTTDTWGVLYDAKNGTVRVDLNDNGDFTDDEVLRPYKDKFQVGYFGKDDPKTDVVEQIPFVVELRKGVPMDPYGGSWVGKKADFVNIGIIEGSHGTHVAGITAANSLFGGKMNGAAPGAKLVSSRACTWSGGCTSVALTEGMIDLAANRGVDIINMSIGGLPALNDGNNARAELYTRIIDAFGVQLVISAGNSGPGANTIGDPSLADKVISVGATISKETWLANYGSEVRKPYAMMPFSSRGPREDGGFTPTLSAPGAAINTTQTWFPGGPTLEAGYDLPAGYSMLQGTSMASPQAAGASALLLSKAKQQGIDLTPAKLRSALTSTATQIDGVQAYEQGAGLINIVDAWKQINKQDGDTHEYTVRAPVDTAIDELLKDPGHGTGVYDREGGLKVGKKRLYDITVTRTTGPKKAVSHKLALVNNHDETFKLVGGKKVDLKLNKPVTLTVSAKAATKGLHSAILTVDDPSTQGTDQQIMTTVVAADELAKPSFTVKKSGEVDRNETRSYFVEVPEGAKSLEVSLGGLFGKSQVRFISIHPYGVPVDSTSTPNCYNNYNNGNGCRPDLRSYADPAPGVWEIEVEARRTSPLLRNPYQLEVSLLGVAFDPAVQTVPEAKVGTPAPVEWKITNENAALEGKLKGGPLGSSLSKRPEIKNGEAQTSEITVGEGVERLDVAIGNVSDVAADLDLTLYDEQGNQVAQTADGDSEEALSVAKPKPGTYTVEVYAYSVPSGSTAYDYRDVYFSAALGEVKVDTAKTVKLATGASAKIAAEVLVAAPAPEGRKFFGQVQVLNAKGTAAGSGSVEIGKVTE
>NZ_CP014485.1|WP_003948057.1|5158963_5160400_-|amino-acid-permease
MTSQPPLAKVEQAPDGPAGPTPAEGQGSDGLQAGLKNRHLSMIAIGGVIGAGLFVGSSAGIAAAGPAILVSYAIVGLMVVLVMRMLGEMAAARPSSGSFSAYADMALGRWAGFSIGWLYWFFWVVVLAVEATAGAVILNGWIPAVPQWGWALIVMVVLTGTNLASVASYGEFEFWFAGIKVVAIAAFVLIGVLAVFGVLPGSDNPGAGFANLTAHGGFLPNGAGSILTGVLMVVFSFMGSEIVTLAAGESANPQRAVRKATNSVIWRIAVFYLGSIFVVVALLPWDSKSIVEDGSYVAALNSIGIPHAGQIMNVIVLTAVLSCLNSGLYTASRMAFSLGKRGDAPAAFARVNARGVPQAAILGSVVFGFAAVWFNYQWPETVFQFLLNSSGAVALFVWLVICFSQLRLRGVIARETPEKLVVRMWLFPYLTWVTIAGIVFVIGYMLFDEAGRTQMALSLLVAVLVVAVSLVKHRGARV
>NZ_CP014485.1|WP_015507891.1|5160772_5161264_+|ribose-5-phosphate-isomerase
MRVYLGSDHAGYELKNHLVDWLKANGHDPVDCGPHVYDAADDYPPFCLRAAERTAADPDSLGIVIGGSGNGEQIAANKVKGVRCALAWSKETAALGREHNNANVVSVGARMHTEEEATDFVATFLATPYSDEARHTRRIDMLSAYETTGELPPIPAHHPQHDA
>NZ_CP014485.1|WP_003948054.1|5162087_5163317_-|GNAT-family-N-acetyltransferase
MTSGAEVLRAEDWDQWYSTLELAFGGVPEAPEERELYQRLTEPERSLVVWDGSEVVGTAGAFTFRVTVPGGRPVAAAGVTMVGVAPTHRRRGILTAMMRRQLDDVRARGEALAMLTASEPGIYGRFGYGIATLKLSAEIDTAQVRLTVPEGTDEVVLRRADPREALKVCEEVYARQVAGRPGMLVRAPGWEEQGLLDPPGNRAGGSPLQCVLAERDGEVVGYTRYRTHPSWGLGGPDGAVTVQDLEASGPAVHAALLRYLCGIDLMRTVKLPSRPVDDAWQYLVSDARRCVPRLGDVLQVRLVEVGAALQQRSYQAPLDVVLEVTDAFCPWNEGRWRLSADAEGAACERTEAEPDLALSVRELGAAYLGGVPLSGLAAAGRVRELRPGALARTSTAFGSDVAPWLPHGF
>NZ_CP014485.1|WP_061404924.1|5164794_5166006_-|cation:proton-antiporter
MGGAFVAAAVLARLGGRIGLPTIPLFILAGILLGPHTPGVVLVSDPHDLEMLSALGLVLLLFYLGLEFHIDDLKAGGRNMALAGGIYLALNVGAGLGFGFALGWGVSEALVLAGVLGFSSSAIVTKILVDTSRLGNPETKPILGIIVVEDVFIALYLAALQPILSGADSLSGALVDGGKAFGFLIALALVARYGTRVVGRLINTPDDEILTISFLGAAVLMAGVSEWFGVADAIGAFMVGLMLGSTTSGKRILKLVHPLRDAFGAIFFFVFGLSINPGDLPGVVWPVLIAVALTLSMNVISGITAARIYRFGAQPAANIATTLLARGEFALILATMAAAAGLDSRLSPFIAGYVLVLAIMAPLAAGRSEWLARVLPGGKPKTTEAGEDDAGASGSSVPERTSV
>NZ_CP014485.1|WP_008411881.1|5166340_5167543_-|acyltransferase-family-protein
MTNSLRPHGHHSQPLPPVQEPADGMTAPRPSPTSQERPPGPERPPAAAAKPAKSRDPFFDNAKYLAIVLVAMGHAWQPLTSDSRAAEALYMVVYAFHMPAFIVISGYFSRSFDMRKDRLQRLVTGVAVPYILFETAYSLFKRWADDDPTHPISLLDPWYLTWFLIALFIWRLTTPLWKIVRWPVPLALALALLASVSPDIGDDLDLQRVLQFLPFFVVGLVLKPEHFQMVRRREVRLLALPVFAAALLVGYWAAPRMSSAWFYHRDSAQEMGFAWWVGVIMTLALFGCSMVLTACFFAWVPRRHMWFTALGAGTLYGYLLHGFLAKGSRFWGWYETYDWVRTPLGMIGVTLIAGAIVTVLCTPPVQRLFRFAMEPKMNWAFKRDATELARERAKSGAAIR
>NZ_CP014485.1|WP_003948050.1|5168316_5168511_+|hypothetical-protein
MAISLSVVVLLAIVMVVLIRGGSLKAGPAVVAILFGFFLASSGMAPAIQRVLDSIAQTVSGISF
>NZ_CP014485.1|WP_003948049.1|5169153_5170551_+|trigger-factor
MKSAVETLNPTRVRLTVEVPFEELKDSLDAAYKKINQQVTVKGFRKGKIPARVIDQRFGRGAVLEEAVNDALPKFYTEAVNEGELNVLGQPEVDITELKDGELLAFTAEVDIRPEIEIPDYSGIEVEVDPVEVTDEDVDKAVEELRERFASTAPVERPAEDGDVVTLDLEAKVDGEVLEDGLASDVSYTIGSGELLDGIDDAVKGLEAGGEATFTSELKGGSAAGKEAEITVKVSKVAKRELPELDDDFAQLASEFDTLEEVRADSRKRLENMKQYDQATQAQERVLDALLELAEVPIPEKLLEDEVNTRKHNLEHHQLGQMGLDLAKYLEIQGKTAEEFDAETREQAIKGIKTQFILDELVNKEKLNVDQEELTEHLMRRAASSGMSPDQFAQAVVEGGQVPMLVGEVARGKALAVVVEAVTVKDTNGEVVDLSDDEDEAAEATEAAAGQTEGDAAEAKADSDK
>NZ_CP014485.1|WP_008411883.1|5170849_5171467_+|ATP-dependent-Clp-protease-proteolytic-subunit
MTNLMPSAAGDPSIGGGLGDQVYNRLLGERIIFLGQPVDDDIANKITAQLLLLASDPDKDINLYINSPGGSISAGMAIYDTMQFIKNDVVTIAMGLAASMGQFLLSAGTPGKRFALPNAEILIHQPSAGLAGSASDIKIHAERLLHTKKRMAELTAFHTGQSVEQITRDSDRDRWFSADEAKEYGLIDEVIASAANVPGGGGTGA
>NZ_CP014485.1|WP_008411884.1|5171534_5172206_+|ATP-dependent-Clp-protease-proteolytic-subunit
MNNFPGSGALGADGEYAGPRAESRYIVPRFVERTSQGVREYDPYAKLFEERVIFLGVQIDDASANDVMAQLLCLESIDPDRDISIYINSPGGSFTALTAIYDTMQFVKPDIQTVCMGQAASAAAVLLAAGSPGKRMALPNARVLIHQPYSETGRGQVSDLEIAANEILRMRAQLEEMLAKHSTTPLDKIRDDIERDKILTAEDALAYGLIDQIVSTRKLNAGV
>NZ_CP014485.1|WP_003948046.1|5172364_5173651_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWDELPKPREIYEFLESYVVGQEPAKKALSVAVYNHYKRVQAGQNGAPGGREDAIELGKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQIDTTNVLFIVGGAFSGLEKIIESRAGAKGIGFGATIRSKREIEEKDQFQEVMPEDLVKFGMIPEFIGRLPVITSVHNLDREALLQILIEPRNALVKQYQRLFELDGVELDFEREALEAIADQAILRQTGARGLRAIMEEVLMSVMYEVPSRKDVARVVITAEVVQSNVNPTLIPRDARGRGNGEQKSA

Crispr_ID: NZ_CP014485_33

• CRISPR_ID: NZ_CP014485_33
• CRISPR_location: 5365276-5365427
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014485_33

Consensus_repeat	Method
CAGCCCGGCCGGCGCTTGAGGCC	CRISPRCasFinder

spacers of NZ_CP014485_33

>33.1|5365299|42|NZ_CP014485|CRISPRCasFinder
ATCTTGAACGGACGAGTCCGATCCGGACCTCGCCCCAAAACC
>33.2|5365364|41|NZ_CP014485|CRISPRCasFinder
GTCCTGAACCGTCAGGTTCCCCCGGGCCCAAGCCCAAAGAT

CRISPR arrays and Neighbor proteins around NZ_CP014485_33

CRISPR arrays

The CRISPR arrays of NZ_CP014485_33

>merge|NZ_CP014485|33|5365276-5365427|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCCATCTTGAACGGACGAGTCCGATCCGGACCTCGCCCCAAAACCCAGCCCGGCCGGCGCTTGAGGCCGTCCTGAACCGTCAGGTTCCCCCGGGCCCAAGCCCAAAGATCAGCCCGGCCGGCGCTTGAGGCC

>NZ_CP014485|33|26|5365276-5365427|CRISPRCasFinder
CAGCCCGGCCGGCGCTTGAGGCC	ATCTTGAACGGACGAGTCCGATCCGGACCTCGCCCCAAAACC
CAGCCCGGCCGGCGCTTGAGGCC	GTCCTGAACCGTCAGGTTCCCCCGGGCCCAAGCCCAAAGAT
CAGCCCGGCCGGCGCTTGAGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061404969.1|5359258_5359933_-|methyltransferase	unknown	unknown	gnl|CDD|184931
NZ_CP014485.1|WP_008408690.1|5361664_5362702_-|rod-shape-determining-protein	unknown	unknown	gnl|CDD|336482
NZ_CP014485.1|WP_061404973.1|5369204_5371688_+|glycoside-hydrolase-family-3-protein	unknown	unknown	gnl|CDD|224389
NZ_CP014485.1|WP_008408687.1|5360269_5360650_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061404970.1|5360744_5361533_-|VOC-family-protein	unknown	unknown	gnl|CDD|319911
NZ_CP014485.1|WP_061404971.1|5364592_5365192_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_010637672.1|5371728_5372628_-|hypothetical-protein	unknown	unknown	gnl|CDD|238870
NZ_CP014485.1|WP_010637689.1|5362878_5364204_+|MFS-transporter	unknown	unknown	gnl|CDD|236700
NZ_CP014485.1|WP_061404967.1|5355837_5356887_-|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187551
NZ_CP014485.1|WP_003947876.1|5365971_5366991_+|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176190
NZ_CP014485.1|WP_015507939.1|5365460_5365883_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP014485.1|WP_003947875.1|5367072_5367501_+|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl|CDD|274649
NZ_CP014485.1|WP_003947869.1|5373726_5374998_-|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl|CDD|238430
NZ_CP014485.1|WP_003947870.1|5373144_5373639_+|DUF3145-domain-containing-protein	unknown	unknown	gnl|CDD|378644
NZ_CP014485.1|WP_061404968.1|5357071_5357956_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187613
NZ_CP014485.1|WP_010637679.1|5367569_5368400_+|EI24-domain-containing-protein	unknown	unknown	gnl|CDD|179898
NZ_CP014485.1|WP_061404972.1|5368419_5368986_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP014485.1|WP_003947884.1|5359032_5359245_-|CDGSH-iron-sulfur-domain-containing-protein	unknown	unknown	gnl|CDD|378163
NZ_CP014485.1|WP_003947885.1|5357995_5359036_-|iron-containing-redox-enzyme-family-protein	unknown	unknown	gnl|CDD|379634
NZ_CP014485.1|WP_003947868.1|5375144_5375393_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|179197

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_061404969.1|5359258_5359933_-|methyltransferase	gnl|CDD|184931	PRK14967, PRK14967, putative methyltransferase; Provisional.	4.95877e-83
NZ_CP014485.1|WP_008408690.1|5361664_5362702_-|rod-shape-determining-protein	gnl|CDD|336482	pfam06723, MreB_Mbl, MreB/Mbl protein. This family consists of bacterial MreB and Mbl proteins as well as two related archaeal sequences. MreB is known to be a rod shape-determining protein in bacteria and goes to make up the bacterial cytoskeleton. Genes coding for MreB/Mbl are only found in elongated bacteria, not in coccoid forms. It has been speculated that constituents of the eukaryotic cytoskeleton (tubulin, actin) may have evolved from prokaryotic precursor proteins closely related to today's bacterial proteins FtsZ and MreB/Mbl.	1.4261e-130
NZ_CP014485.1|WP_061404973.1|5369204_5371688_+|glycoside-hydrolase-family-3-protein	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	4.38771e-63
NZ_CP014485.1|WP_003947884.1|5359032_5359245_-|CDGSH-iron-sulfur-domain-containing-protein	gnl|CDD|378163	pfam09360, zf-CDGSH, Iron-binding zinc finger CDGSH type. The CDGSH-type zinc finger domain binds iron rather than zinc as a redox-active pH-labile 2Fe-2S cluster. The conserved sequence C-X-C-X2-(S/T)-X3-P-X-C-D-G-(S/A/T)-H is a defining feature of this family. The domain is oriented towards the cytoplasm and is tethered to the mitochondrial membrane by a more N-terminal domain found in higher vertebrates, MitoNEET_N, pfam10660. The domain forms a uniquely folded homo-dimer and spans the outer mitochondrial membrane, orienting the iron-binding residues towards the cytoplasm.	1.18255e-15
NZ_CP014485.1|WP_010637672.1|5371728_5372628_-|hypothetical-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	1.36119e-23
NZ_CP014485.1|WP_061404970.1|5360744_5361533_-|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.68384e-28
NZ_CP014485.1|WP_010637689.1|5362878_5364204_+|MFS-transporter	gnl|CDD|236700	PRK10489, PRK10489, enterobactin transporter EntS.	1.21394e-72
NZ_CP014485.1|WP_061404967.1|5355837_5356887_-|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187551	cd05240, UDP_G4E_3_SDR_e, UDP-glucose 4 epimerase (G4E), subgroup 3, extended (e) SDRs. Members of this bacterial subgroup are identified as possible sugar epimerases, such as UDP-glucose 4 epimerase. However, while the NAD(P)-binding motif is fairly well conserved, not all members retain the canonical active site tetrad of the extended SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.3155e-78
NZ_CP014485.1|WP_003947876.1|5365971_5366991_+|NADP-dependent-oxidoreductase	gnl|CDD|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	0
NZ_CP014485.1|WP_015507939.1|5365460_5365883_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.20978e-15
NZ_CP014485.1|WP_003947875.1|5367072_5367501_+|organic-hydroperoxide-resistance-protein	gnl|CDD|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	9.82691e-73
NZ_CP014485.1|WP_003947869.1|5373726_5374998_-|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl|CDD|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	0
NZ_CP014485.1|WP_003947870.1|5373144_5373639_+|DUF3145-domain-containing-protein	gnl|CDD|378644	pfam11343, DUF3145, Protein of unknown function (DUF3145). This family of proteins with unknown function appear to be restricted to Actinobacteria.	1.83132e-97
NZ_CP014485.1|WP_010637679.1|5367569_5368400_+|EI24-domain-containing-protein	gnl|CDD|179898	PRK04949, PRK04949, putative sulfate transport protein CysZ; Validated.	5.47043e-22
NZ_CP014485.1|WP_061404972.1|5368419_5368986_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	7.12973e-12
NZ_CP014485.1|WP_061404968.1|5357071_5357956_-|SDR-family-oxidoreductase	gnl|CDD|187613	cd05355, SDR_c1, classical (c) SDR, subgroup 1. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	8.89619e-149
NZ_CP014485.1|WP_003947885.1|5357995_5359036_-|iron-containing-redox-enzyme-family-protein	gnl|CDD|379634	pfam14518, Haem_oxygenas_2, Iron-containing redox enzyme. The CADD, Chlamydia protein associating with death domains, crystal structure reveals a dimer of seven-helical bundles. Each bundle contains a di-iron centre adjacent to an internal cavity that forms an active site similar to that of methane mono-oxygenase hydrolase.	2.91329e-51
NZ_CP014485.1|WP_003947868.1|5375144_5375393_-|acyl-carrier-protein	gnl|CDD|179197	PRK00982, acpP, acyl carrier protein; Provisional.	2.40477e-27

Protein sequences

>NZ_CP014485.1|WP_061404971.1|5364592_5365192_-|hypothetical-protein
MCAAVGGTSSFGSLEFQLVLLRRMADFQAGMVEEARRELGVDAGAMREANRRWQAMVRSPRGRRRAGVLRSVLGVPEAVERRVVGDLECEALRWPVVLWPALRFEAVVAPGGALWNEWLVRGPGDAPPAPAALDALRPWEYTVEEVARAFPARPMQGSAPTRWRLRVTAPEYEGGPVRDAVAEFTWGLLQEVTVMEGRE
>NZ_CP014485.1|WP_010637689.1|5362878_5364204_+|MFS-transporter
MHSETSKDEPPAPDDAQAILPSPRDPVAAPPRKRLLADLTPLRTSADFRRLWIGNTISWVGQGMTALAISLQVYDLTRSSFSVGLVGLFSLVPLVVFGLYGGAIADTVDRRLLGLASSTGSWLLAVALAVAAFAGFHQVWFLYAVVALQAVCAALNSPARTSMIPRLLPAEQLPAANALNSMTTTFGTMTGPMLGGALVGLWGYQAAYLIDAVAFTAALYAMWRLPAMRPQREEGSRGRASVLDGLRFLATRPNIRMTFFTDLCAMVLAHPRALFPAVAVVWYGGDAKTAGLLVAAPAVGALLGSVFSGWLGRVHRHGVAILLAVGGWGLAVAVFGLTRNLWLGLLFLALAGAADAISMVFRSTMLQAATPDAMRGRLQGVFIVVVAGGPRLGDFLAGSVGDLASPTVAVTGGGLLCVLAVTALGLRWRNFARYDARDPQP
>NZ_CP014485.1|WP_008408690.1|5361664_5362702_-|rod-shape-determining-protein
MTASLEQLRRCHFAVDLGAARTRVFIKGEGVVVDEPSAAAINTRTGALIAVGTLAEQMTGRTPGYIRVVRPVKGGTVIDIDMAQRMLRHLLGDKVRRALRRKPRLRAAACTPHDADPLAQRATVETLVGIGARRVELVDTLIAAAVGCGLPVERPEASMILVCGAATTQIAVLSLGSIVTAERVPVGGNAIDHSVLSYLRHHHELMLPSQSVRPLHVALRGGDLSMTGSGTTEIHGRDVATGLARSVEVDTVGLRSAISIPLTGVLDGIGKVLRDCPPDLVADLADRGIMMVGGSALMPGLDQMIREATGMPVQVAERPDIASVTGLGAMLDGLIEPMTLNPLSA
>NZ_CP014485.1|WP_061404970.1|5360744_5361533_-|VOC-family-protein
MSPFPDGAPCWADAMFPDLAAARDFYGQVLGWTFDDLGEEYGNYTMALVDGKPVAALMPVMPGPDAPALWNLYLATSDAAAVTGRVEGLGGTVAMGPEDVGGFGITSSLRDPAGTAFSLWQPNTHPGFGLTEVPGAYAWAEVYTRDAAATDRFFPELFGYQVGVMEDPEMDFRIWSVAGRPVLGRMAMADDFPPEVPSYVNVYFSVPDCDAALDTAVRLGGQVHYGPTTTPFGRFAAVSDQQGASFSVIDTGTTEGEMPPMT
>NZ_CP014485.1|WP_008408687.1|5360269_5360650_+|hypothetical-protein
MYAMTEVQILGASESGGIGWALGIGLAVLAVAVVGMLIWVVRKGIKQRATDPEPPSPESQPRKPDRPTHEEAYREDDEGEFPTDGGRVLPHEMKGVSSHQAEPPEGGRPKHTPGHSGGFGSGGAGG
>NZ_CP014485.1|WP_061404969.1|5359258_5359933_-|methyltransferase
MTSAPAPPLSPVLAPAGVYAPQHDTALLTRAVTAEQPGPGTEVLDLGTGTGAVALHAARTGARVTAVDISWTAVLTARLNAARARCRLRVHRGDLTAPVTGRTFDLVVSNPPYVPAPEETPPASGPARAWDAGPDGRALLDRICADAPAALRPGGTLLLVHSALCGTEATLSRLAAAGMRAEVSDRVRIPYGPVLTGRHEWLVARGLADGTPWEELVIVRAVHA
>NZ_CP014485.1|WP_003947884.1|5359032_5359245_-|CDGSH-iron-sulfur-domain-containing-protein
MRLDPDGGPLLVDGPVEVVTEDGTTHFSHRPTVALCTCRRSARYPWCDTSHRARAPERADAPDSPEEEPR
>NZ_CP014485.1|WP_003947885.1|5357995_5359036_-|iron-containing-redox-enzyme-family-protein
MTTPARSRLTRPRLPEPRGPVSAGVVEALRSGGSPVTDGAEATADPYGEDLQLALYVLYELHYQGFAGAPADDSREWDPELLALRATLEQPFLAALRADAERPASAAAALDALLVEPAGHRPGSVSHHLRRTHRLPELREYAALRSLYHLKEADPHAWMIPRLRGRAKAGLAAVEYDEFGAGRAEDVHARLYAELMAELGLEPAYGHYLDAAPAAALATVNLMSLFGLHRALRGALVGHFAAVEVTSSPGSRRLADALRKAGAGPAAVRFYEEHVEADAVHEQVVRRDVVAGLLADEPELDADVAFGVAATSLLEDRLGALLLDAWTQDRSALLPGHHADAVARPA
>NZ_CP014485.1|WP_061404968.1|5357071_5357956_-|SDR-family-oxidoreductase
MTDPRGHQDAAGDRPRPPQPEQSQEHPGSTARMDPVPDHGEESYRGRGLLRDRRALLTGGDSGIGRAVALAFAREGADLVFAHLPEERDEARVTLRLITEAGRTGIAVPCDIRDEETCRELVARTVAELGGLDLLVNNAAYQMSQPEGIEAITTEQFDRVMRTNLYAMFWLCREARPHLGPGSAIINTTSVQGFQPSPHLLDYAMTKGAITTFTHGLAQMLAADGIRVNAIAPGPVWTPLIPSTLPSTEEFGAQSPLGRAAQPAELAPAYVFLASDQASYITGEIMNVTGGQPL
>NZ_CP014485.1|WP_061404967.1|5355837_5356887_-|NAD-dependent-epimerase/dehydratase-family-protein
MTSSTPKPLRVVVTGATGNVGTSVMRRLAEEPRVVSALGLARRTPRLSYPGVEWAACYLTAPEAPDQLLRLFEGADAVVHLAWRFQPTRDAAVTWEANVLGSLRVFEAAATVGVPALVHASSVGAYAPGPADGHRVDESWPTHGWPGAAYTREKAYLERVLDTFERDHPDTRVVRMRPAFLFKESAAGEQLRIFGHRLLPGRLLRPDLLPVLPGVRGLRFQALHTDDAADAYARAVVQEVRGPFNLAADPVIDGQVLAALLESRSVELPPALPRAALSAGWRLRALGASPGLFDAVLRLPLLDTARARAELGWSPEHSATEALDAFLRGVRSHGGLPTAPLAGHEPAAA
>NZ_CP014485.1|WP_015507939.1|5365460_5365883_-|MarR-family-transcriptional-regulator
MATRTDPLTLEVVELIGAVVARYHEEYDRAAAEQALTGAQARVLGLLSLEAMPMRQIARRLKCEPSNVTGIVDRLALRGLVERQADPGDRRIKVAALTAEGREVARVLRDSLDFAREPLAGFSREEREVLRGMLRRMAGE
>NZ_CP014485.1|WP_003947876.1|5365971_5366991_+|NADP-dependent-oxidoreductase
MTALPSSGREWHLVARPDGWPTPEDFALREVPVEAPTAGRILVRNLYFSVDPYMRGRMNDVKSYVPPFQLDAPMDGGAVGEVIASEAEGFAVGDHVLHGLGWREYANLPAKHAKKVDGSLAPLSAYLGVLGMPGLTAYAGLLDVASFKPGDAVFVSGAAGAVGSEVGQIARLKGASRVIGSAGSDEKVKLLVDEYGFDAAFNYKNGPVAEQLKEAAPDGIDVYFDNVGGDHLEAALGRLNQFGRVALCGAIAQYNDKGAPTGPRNLALAIGKRLRLQGFIVGDHSDLQPQFVDEVSGWVRSGELKYNETFVEGIDNGVEGFLGMLRGENTGKMIIDLSR
>NZ_CP014485.1|WP_003947875.1|5367072_5367501_+|organic-hydroperoxide-resistance-protein
MSIQHIDVAYTAVATAENGRDGRVATDDGKLDVVVNPPKEMGGSGAGTNPEQLFAAGYSACFQGALGVVARAAKADIKGSTVTAQVGIGKAEAGGFGLEVELITSIPNVDRATAEELVAKAHEVCPYSNATRGNIKVTLTVA
>NZ_CP014485.1|WP_010637679.1|5367569_5368400_+|EI24-domain-containing-protein
MGDLGVGFRYLMNGQRWALSHGKTFGLGLLPGLITLVVYAAALVALAFGADDLIAWATPFADGWGSPWLGLFRGFLTAVLFALGLMLAVITFTSVTLLVGSPFYDAVSERVDASIDGNVPTSGRSFWYDLWVSTRDSLRILVRAAIWGVLLFALGFIPVVGQTAIPVAGFFVTGFFLTEELASVALARRDVDLRGRLTLLRSRRMLAWGFGVPLALAYVIPFVAVFLMPGAVAGATLLSRDLLGEPTAPTADAVPGTGEAAPAGLAKPPADTPAER
>NZ_CP014485.1|WP_061404972.1|5368419_5368986_-|TetR/AcrR-family-transcriptional-regulator
MSRGGRNEDRRGEILRAALEVISERGYRAASLAAVAERVGLTQQGLLHHFPTKEALLVGVLEARDQWDATPRESWRLDLLAALVDYNATRPAIVRTFSALLGESVTGDHPARAYFTGRYAVVRADMAAILRTAYGERLPSGLTPEQAAPLLVAVMDGLQYQWLLDPEAVDMTAAFRDFLVLLGEEPLS
>NZ_CP014485.1|WP_061404973.1|5369204_5371688_+|glycoside-hydrolase-family-3-protein
MTDHPGKEYEDRLDEAVEAAFAALDLDAKSRLLAGQDMWSLPALPEAGVGSLVMSDGPVGVRGVRWTAADPSVALPSPTALAASWDPELARRAGVLLAQEARRKGVHVLLAPTVNLHRSPLGGRHFETYSEDPYLTGAIGTGYVQGVQSGGVGTTVKHFAGNDAETERFTVDNRIDARTLREVYLAPFETITTEARPWGVMTAYNSVNGTTMTEHHELVTGVLRGEWGFDGINVSDWLAARSTGPALTAGLDLAMPGPRTVHGPALAAAVRAGQVDEAYVDAAVRRVLRLAGRVGILDGVGPAVGPGHLPAEVDGAAVAREVARRGFVLLRNAPTADGTPVLPLGPEPGTVALIGAAAREARALGGGSATVFPPHLTSPLEGLRAALGEEAVTFRVGADPQTDLGPATQGFDLRAVCRDAEGTVLGTAPVPGGAVQWVGSDLPEGVTHDTLHSIEITGTYTPPESGRHTFGTRGLGAFRLTVDGRELWSGSQGLGEARDPFEAFFGAPTERATAHLTAGTPVDLSLEYVRTRLPDAPLEGVSVSLVHLLPQRDPDELIAEAAEAARQAETAVVVVATTEAVESEGFDRTSLALPGRQDDLVRAVVAANPRTVVVVNAGSPVEMAWREEAAAVLLTWFPGQEGGSALADVLLGHEEPGGRLPTTWPARLADAPVTDTTPTDGRLDYTEGVFVGYAAWERVGTTPAYPFGHGLGYTDWAYETLRAQGRTVTVGLRNTGTRPGRETVQLYLAPPPAAPGEPERPAQRLAGFALAEAGSGESTEVTVELPGRAFQIWDEAAGGWSHRPGRYEVRAGRSAADPRLTLALQED
>NZ_CP014485.1|WP_010637672.1|5371728_5372628_-|hypothetical-protein
MGERGVRGRRRRAGTAAALAVLLGAVLPACGSAPSSSQGSDEQAAPRARQQTGWDTRPASLAAVGDSITRGFDACSVLADCPEASWATGSDPGVRSLALRLLGERGAAERSWNHAVSGARAADLPAQVERAVQDRPELLTVMVGANDACRTSTRHMTKVKDFRKSVEEAMEIVREELPRTQVYMASVPDLKRLWSEGRTSELGKQVWALGICRSMLSKPDAVDKKSVKRRAKVHKRVKAYNRVLAEVCGQDRLCRTDGGAVFDFRFTGTQLSPWDWFHPSKNGQAHIARIAYRAVTAKG
>NZ_CP014485.1|WP_003947870.1|5373144_5373639_+|DUF3145-domain-containing-protein
MTTRGVLYVHSAPRALCPHVEWAVAGVLGVRVSLDWIRQPAAPGTWRAEFSWQGQAGIASRLASALRGWQQLRFEVTAEPSPGAEGERYSSTPGLGIFHAVTGIHGDILVPEDRLRAALVRSQAGETDLEAEIARLLGKPWDDELEPFRHAGEGAPVRWLHQVV
>NZ_CP014485.1|WP_003947869.1|5373726_5374998_-|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MSPTNRTVVVTGIGATTPLGGDAASTWEGLIAGRSGVRPLDDERYADLPVRIAAQIAVEPAEVLPRPLVRKLDRSAQFALIAAREAWADAGYTAMAGEDEQISPERLGTVIASGIGGVTTLLDQYDVLKEKGARRVSPHTVPMLMPNSPSANVGLEVNARAGVHTPVSACASGAEAIGYAVEMIRTGRADVVVAGGTEAAIHPLPVVAFANMMAMSKNNDEPEKASRPYDTGRDGFVLGEGAGVVVLESAEHAAARGASVYCEVLGQGLSADSHHIAQPEPTGRGIAAALQHLMDDTDLKPSEVVHLNAHATSTPQGDIAEVKALRQILGEDLEHVAISATKSMTGHLLGGAGGIETVATVLALKHRKAPPTLNVDELDPAITEAGADVVRGEARELPEGTVAAINNSFGFGGHNVVLAFRTV
>NZ_CP014485.1|WP_003947868.1|5375144_5375393_-|acyl-carrier-protein
MAATQEEIVDGLAEIVNEIAGIPVEDVQLDKSFTDDLDVDSLSMVEVVVAAEERFDVKIPDEDVKNLKTVGDATSYILKHQG

Crispr_ID: NZ_CP014485_34

• CRISPR_ID: NZ_CP014485_34
• CRISPR_location: 5526207-5526303
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_34

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP014485_34

>34.1|5526230|51|NZ_CP014485|CRISPRCasFinder
TGGATTGGGCTGGGATGTGGCTGCGGGTGGTTGTCCGCTGCGGGTCACGGA

CRISPR arrays and Neighbor proteins around NZ_CP014485_34

CRISPR arrays

The CRISPR arrays of NZ_CP014485_34

>merge|NZ_CP014485|34|5526207-5526303|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTTGGATTGGGCTGGGATGTGGCTGCGGGTGGTTGTCCGCTGCGGGTCACGGATGGCCTCAAGCGCCGGCCGGGCT

>NZ_CP014485|34|27|5526207-5526303|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCT	TGGATTGGGCTGGGATGTGGCTGCGGGTGGTTGTCCGCTGCGGGTCACGGA
TGGCCTCAAGCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003947738.1|5531631_5532246_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|367243
NZ_CP014485.1|WP_049977567.1|5514340_5516098_-|NAD+-synthase	unknown	unknown	gnl|CDD|237577
NZ_CP014485.1|WP_031178125.1|5517916_5518411_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008409232.1|5536758_5537832_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP014485.1|WP_003947735.1|5535122_5535536_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_079055385.1|5522042_5523296_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197775
NZ_CP014485.1|WP_061405040.1|5530697_5531618_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_018470694.1|5523310_5523682_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003947731.1|5539527_5540538_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP014485.1|WP_026235343.1|5538160_5539444_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270454
NZ_CP014485.1|WP_061405041.1|5533523_5535104_+|amidohydrolase	unknown	unknown	gnl|CDD|238625
NZ_CP014485.1|WP_008413091.1|5523762_5524386_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
NZ_CP014485.1|WP_061405037.1|5516202_5517822_-|multicopper-oxidase-family-protein	unknown	unknown	gnl|CDD|225043
NZ_CP014485.1|WP_061405042.1|5535661_5536630_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|379588
NZ_CP014485.1|WP_061405039.1|5526362_5526947_-|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|334450
NZ_CP014485.1|WP_010637478.1|5527227_5530233_+|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase	unknown	unknown	gnl|CDD|237613
NZ_CP014485.1|WP_003947746.1|5519094_5519763_-|DUF3105-domain-containing-protein	unknown	unknown	gnl|CDD|378632
NZ_CP014485.1|WP_061405038.1|5524505_5526113_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP014485.1|WP_079076038.1|5518474_5519098_-|DUF305-domain-containing-protein	unknown	unknown	gnl|CDD|367619
NZ_CP014485.1|WP_003947745.1|5519939_5521301_+|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl|CDD|223252

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003947738.1|5531631_5532246_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	3.61346e-09
NZ_CP014485.1|WP_049977567.1|5514340_5516098_-|NAD+-synthase	gnl|CDD|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0
NZ_CP014485.1|WP_026235343.1|5538160_5539444_+|extracellular-solute-binding-protein	gnl|CDD|270454	cd14751, PBP2_GacH, The periplasmic-binding component of the putative oligosacchride ABC transporter GacHFG; possesses type 2 periplasmic binding fold. This group represents the periplasmic component GacH of an ABC import system. GacH is identified as a maltose/maltodextrin-binding protein with a low affinity for acarbose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.69215e-153
NZ_CP014485.1|WP_008409232.1|5536758_5537832_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.18974e-94
NZ_CP014485.1|WP_079055385.1|5522042_5523296_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.73631e-10
NZ_CP014485.1|WP_003947731.1|5539527_5540538_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	4.69732e-91
NZ_CP014485.1|WP_061405041.1|5533523_5535104_+|amidohydrolase	gnl|CDD|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	1.34521e-113
NZ_CP014485.1|WP_008413091.1|5523762_5524386_-|TetR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	1.89795e-11
NZ_CP014485.1|WP_061405037.1|5516202_5517822_-|multicopper-oxidase-family-protein	gnl|CDD|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	6.16581e-89
NZ_CP014485.1|WP_061405042.1|5535661_5536630_-|phosphatase-PAP2-family-protein	gnl|CDD|379588	pfam14378, PAP2_3, PAP2 superfamily.	9.75199e-52
NZ_CP014485.1|WP_061405039.1|5526362_5526947_-|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	2.47625e-13
NZ_CP014485.1|WP_010637478.1|5527227_5530233_+|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase	gnl|CDD|237613	PRK14109, PRK14109, bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase.	0
NZ_CP014485.1|WP_003947746.1|5519094_5519763_-|DUF3105-domain-containing-protein	gnl|CDD|378632	pfam11303, DUF3105, Protein of unknown function (DUF3105). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	4.56688e-61
NZ_CP014485.1|WP_061405038.1|5524505_5526113_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	9.69633e-59
NZ_CP014485.1|WP_079076038.1|5518474_5519098_-|DUF305-domain-containing-protein	gnl|CDD|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	4.24319e-46
NZ_CP014485.1|WP_003947745.1|5519939_5521301_+|type-I-glutamate--ammonia-ligase	gnl|CDD|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	0

Protein sequences

>NZ_CP014485.1|WP_061405038.1|5524505_5526113_+|MFS-transporter
MSAHSAAAPTAAAPMDHRHVMRAFSGLLVVLFVAMISGTVVSVALPQIIGSLDGTQSQYTWVVTATLLASTASTPIWGKLADLFSKKLLLQIAIGLFIVASLACGLAQNTGQLIGFRVIQGLGMGALQVLVQVIIAAMISPKERGRYNGYLGGVMAVATVGGPLLGGFITDTSWLGWRWCFFIAVPFTLIALVMLTRTLHLDEIKRPDTKVDYLGAALIAAGVSLLLLWVTFVGNNFDWISWQTLAMVAGSVLLLGAAVTVEAKVAEPIVPLHVVRRRDPALAIVASLAVGMAMFGGAVFLGQYFQIGRGYSPTEAGLLTIPMMAGVLISSTVAGRLVSKSGKVKPYIIAGVVLLTVGFLGLSLIDHKTSLVGVSLGMLAVGAGVGMSMQNLVLVLQNTVPLSELGAASGSITFFRSLGGTVGVSVLGAVLANQVSAKIADGLSRIGVDPAAGGSGSGTLNIAAMPPQIQEIVRAAYGEATGHIFLISAGIALIGVVATLFLTPTRLRDSVDLADGSGDAGGAGEAGERVPAAAG
>NZ_CP014485.1|WP_008413091.1|5523762_5524386_-|TetR-family-transcriptional-regulator
MDSTEETPAATPDAPLGLRERKKAATRQAVHEAAMRLTREHGLDHVTVEAIADAAGISRRTFSNYFAGKEDALLYGKEQYIQRLLDAVRDRPAEETNWQALRAATQVLRDPRLDPPRREWAQQTRLAMSHPSLLGRQLSTLATLESDLAATLTARSPTDPVRARVMAAAFLVALRIAMQLWIEENEQAEDPMELMMITMDEMGARFV
>NZ_CP014485.1|WP_018470694.1|5523310_5523682_+|hypothetical-protein
MSEVDGARLFREGWIAGVRRHFPGEPKAGYVTPWEGTPEWEREAAGAVCAQVRQFVEVSAGKAGRLSREQKGRFVATCWTAQMYKHFEEPKPGYVADWAELPKWQQETDADIFEAIERHFPPS
>NZ_CP014485.1|WP_079055385.1|5522042_5523296_+|helix-turn-helix-transcriptional-regulator
MGLAERRRARGYRQEKLAHLLGVDRTTVGRWESGRVFPQPPQRRGLAHALGLSLDELDCLLAMPAVRVQETARCQTEESPTPGDSDEMMRRAFLRVLSVSGALAVLPVDEAEALQEGAGLGASADFDRMNGHLWQVYQLARSKKAVHPVVRDQLSMLNEALASGRGPTRSLLSAAADLFQLAGEVAFDGNRYSEAASSYALAASVGREADAYDLWACALVRHAYVEMSEGRHRQAVQLLGAAARLARRGDSALSTRQWVASVQAEAYAGLGDLTACERAMDQAETVRELAGGSANGGWLRFDGARLSEERGARYVQLGRFDRAEETLTGALKQSDLAAGHSYRRRGAVLTDLAVIGVRRGDAEQVVAYGGEAVGLARATGSGYVVHRLQALRGELGSLSEDRRVAGLGAEIAALGMS
>NZ_CP014485.1|WP_003947745.1|5519939_5521301_+|type-I-glutamate--ammonia-ligase
MDKQQEFVLRTLEERDIRFVRLWFTDVLGFLKSVAVAPAELEQAFDEGIGFDGSAIEGFARVYESDMIAKPDPATFQVLPWRAEAPGTARMFCDILMPDGSPSFADPRYVLKRALAKTSDLGFTFYTHPEIEFFLLKNKPVDGSRPVPADSSGYFDHTPQNVGMDFRRQAITMLESMGISVEFSHHEGAPGQQEIDLRYADALSTADNIMTFRLVMKQVALEQGVQASFMPKPFSEYPGSGMHTHLSLFEGDRNAFYESGAEYQLSKVGRSFIAGLLRHAAEISAVTNQWVNSYKRIWGGSARSAGAGGEAPSYICWGHNNRSALIRVPMYKPGKTGSARVEVRSLDSGANPYLSYAVLLAAGLKGIEEGYELPPGADDDVWALSDAERRAMGIEPLPQNLGEAISLMERSELVAETLGEHVYDFFLRNKKQEWEEYRSEVTAFELKNLLPVL
>NZ_CP014485.1|WP_003947746.1|5519094_5519763_-|DUF3105-domain-containing-protein
MGSTRNTPGSAEDRRARIQRMRASEQARERRNRLLFIGVSTLVVVGLIGGGGYLYLQKADEKEQTAAAEKEQAEKPVKDEKSWKAEELGRDHVSTPVSYPMTPPVGGDHNQVWMNCDGDVYEKPIPDVNAVHSLEHGAVWVTHNGDADPADVDKLTERVKSTPYSLMSPVEKQEGALMLSAWGKQVTVDSADDPRVAQFFTKYVQGPQTPEPGAACTGGLSS
>NZ_CP014485.1|WP_079076038.1|5518474_5519098_-|DUF305-domain-containing-protein
MRTRTALAAGAAAVLMALGSVVTVAAAGGEEPPPAPAVPASDSADAGFARDMAVHHQQAVEMSFLVRDSTDGEEIRTLAYDIANTQANQRGMMLGWLDLWGLPKVSEDPPMAWMGMRHKPGKDGALMPGMATRAELDRLRKTEGEAAEILYLRLMTAHHKGGIHMAEGCVSACEVPAEKRLAQGMVDAQQSEIDLMAELLRKRGVRD
>NZ_CP014485.1|WP_031178125.1|5517916_5518411_-|hypothetical-protein
MRTRTGTAAGRAGRLLLLAALLLGVLTMHTLGHPTGDHGGAHSGAHGAAHGPGTVAAAPAAPAGSGAAEHHSPAAGIAAEAAAGAVTGTPDSSDPLPGTDPLSVCLAVLAALTLGLLLRAGGLLGGGAAPGSAARVLLTGRRGAQWPIAPPTRLALARLSVLRI
>NZ_CP014485.1|WP_061405037.1|5516202_5517822_-|multicopper-oxidase-family-protein
MRTPTRRSLLGAGLGLAGTGLLAACSSSGGTSSDHGSGSGATTGAGDWIDPAGREVADAEKARAGGGRVREVRLTATETRLDLGPVTVPTWAYGDRLPGREVRVTAGDTLSLTLANHLPEPTSLHWHGLALRNDMDGVPGLTQKDVRPGADFTYRFTVPHPGTYWFHPHSGTQQDRGLYAPLIVEDPKEPLAYDHEWVVVVDDWVDGVEGSTPDGVLKELSRGMAPGMDHGSGDGGEEGDEGGGHSGHGMSAQEARTEEPGGPSRMMMGARSDLLGGDAGDVKYPYHLVNGRTAEAPEVFRAKPGDRIRVRLVNAGGDTAYRVALGGHRMTVTHTDGFAVEHAETDALLLGMGERYDVLVTAGDGVFPLTALAEGKDATARALLRTGGGAAPKAGARPRELDGKVLTADRLVAAGPAALPARTPDRTVRFQLTGGMARYDWAFNGRPYKASERYPVRAGERVRLVFSNATDMWHPLHLHGHTFALSSAKGAPRKDTAVILPHRTLTADFDADNPGLWMLHCHNVYHAEAGMMTVLGYRR
>NZ_CP014485.1|WP_049977567.1|5514340_5516098_-|NAD+-synthase
MHRLRLALNQIDATVGDLHGNADAVVHRTREAAERGAHLVAFPEMVLTGYPVEDLALRSSFVEASRSALVALAARLADEGLGDVPVVVGYLDRSSTAQPRYGQPAGAPQNAAAVLHGGEVVLSFAKHHLPNYGVFDEFRYFVPGDTMPVIRVRGVDVALAICEDLWQEGGRVPAARAAGAGLLLSVNASPYEREKDDTRLALVRKRAQEAGCATAYVAMTGGQDELVFDGDTIVVDASGAVLARAPQFTEVQLVLDLDLPAAAADAPEGTVDDGLRIDRVILSGEPVAGPGPVEYPGTTVPPLDDDEEVYRALVTGLRAYVRKNGFRSVLIGLSGGIDSALTAALAVDAIGAEHVYGVSMPSKYSSEHSKDDAAELARRTGLHYRTVSIAPMFDAYMGELGLTGLAEENLQSRLRGTTLMAISNQEGQIVLAPGNKSELAVGYSTLYGDSVGAYGPIKDVYKSTVFRLARWRNEVAAERGETPPIPENSVTKPPSAELRPGQVDTDSLPDYDVLDAILARYVDRDEGRDEILAAGFDPETVTRVLKLVDNAEYKRRQYPPGTKISAKGFGKDRRLPITSRWRESG
>NZ_CP014485.1|WP_061405039.1|5526362_5526947_-|pyridoxamine-5'-phosphate-oxidase-family-protein
MGTHPDTDADTNTTAAAPAGHGGSAQRPVSTTLDPRYSTPDAEAVPWSTAEDLLRRSEIFWLTTVRPDGRPHVTPLLAVWQHGALHFATGAEERKARNLAQNQQVILTTGTNTLSDGLDLVVEGEACLVSDTDRLTSLATAWSTKYGPDWAFEVADGTFHHPDGASALVFAVPPHRVFGFTKGTPFSQTRWNFT
>NZ_CP014485.1|WP_010637478.1|5527227_5530233_+|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase
MTIPQGRRSSTFTRLLRHGFTDPSTAERLLGSEALAPVAEDTVLLDALAATADPDLALLGLVRLAEAEPEEERQRLLSTVVTAKPLRDRLLGVLGASEALGDHLARHPQDWRALAIYESADLHPGVEEFTRGLADATDPDSLRVAYRRCLLSIAARDVCGTIDVAETAAELADLATATLRAALRIAEAAAPEDAARCRLAVIAMGKCGGHELNYVSDVDVIFVAEPADSGDADEAPALQAANRLAAHLMRICSETTVEGTIWPVDANLRPEGRNGPLVRTLSSHLAYYQRWAKTWEFQALLKARPVAGDAELGAAYIETIAPLVWQAAERDNFVPDVQKMRRRVVDTIPAHEIERELKLGPGGLRDVEFAVQLLQLVHGRSDPSLRSGTTLDALAALAAGGYVGRTDAAQLDDAYRFLRSMEHRIQLYRLRRTHLVPEGEADLRRLGRSLGLRTEPVVALNRAWRRHAGVVRRLHEKLFYRPLLDAVAQLAPGEARLSTEAARERLVALGYDDPSDALRHLEALASGVSRKAAIQRTLLPVLLGWFADSADPDAGLLNFRKVSDALGQTPWYLRLLRDEGAAAENLARVLSAGRLAPDLLMRAPEAVALLGDVRGLEPRGRAQLEQEVLAAVRRSDNAEHAVAVARGVRRRELFRTAAGDLIGSYGTEESPAEADPGALVDRVGSALSDLNAATLAGTLRAVVRDGWGDTLPTRFTVIGMGRFGGHEQGYGSDADVLFVHEPREGVDEQEAAKAANRVVAELRRLLEIPSADPPLVIDPDLRPEGKTGPLVRTLASYAAYYRRWSQVWEAQALLRAEPVAGDDELGARFVELVDPLRYPAEGLGEDGAREIRRLKARMESERLPRGADPTLHTKLGRGGLSDVEWTVQLLQMRHGAAEPGLRTTSTRPALAAAVAAGLLPAEEAAMLDEAWVLATRVRNAVMLVRGRPGDTFPSDGRELAAVARYLGYEPGHVGDMLDDYRRTTRRARAVVDEVFYGAGAH
>NZ_CP014485.1|WP_061405040.1|5530697_5531618_+|hypothetical-protein
MPTPRFWRVWWRGLAAVVVMIVIAIVGGTLSGADEDEEAEGVYAQVRLVLADQLRPRDCVLAGSLFDLDPRERAAAEKVSVTSCWGPHDGVVFGRLPLAGTAAETSEGGFAGPAKVREVARLGCAERFAEEAQDPYSHDFTIQALYPVTGTEWEKGRRTVVCWASAKGLFQEGEDGMSLFDHHNLDEQQEAFHQALKPLTRARAERPDEEESLRTERRWAASMKRAVEEAVHRLRFDDGMGHFGTAAAADLADVLATQVPAWDAAAKAKDADAYSDAWGEAELEHSFGTEMAEARQVLLLPPVITE
>NZ_CP014485.1|WP_003947738.1|5531631_5532246_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MGRPRTPLIDRPRIATVALELVDANGEFSVPAIARRLGVQTGSLYHHVDGRDGVIELIRERVTEAIDVSTLSAPTWDTALQDWARSYRAAFAAHPKVIPLLTTHPVRAPGMLDQYERVVRVLMDAGFATVDVMPLITALENTVLGSALDLAAPETMWEPADTTSTPRLSQALAAIGEGRADAAFEIALAAFMGYARGVLEGYEG
>NZ_CP014485.1|WP_061405041.1|5533523_5535104_+|amidohydrolase
MPAADLVLTAARVHTLDPARPRAEAVAVKDGTIVAVGDRTDTADWTGPGTDTVDLGGATLTPGLVDAHSHPVWGLEMAAGTDLSAVTGLDGLRAALHTATPTDGWLLGWGLDHNAFGDQPLDRRLIEDIHPGVPVFLRLYDGHSALVNGAALDRAGITGPRTFGQRASVVCDTDGRPTGHLIEHAAMDLVQPHLPTPSDAERIARLRTLLGEMAATGLTGAHVMDLGDGTVPELLTAFEAEGELPLRLRLAPWCMPGSTPADLAELIALQSRAGRLWRVGGVKFFMDGTVEGGTAWLEHADCHGQGTDAFWPDPEAYSAAVRTLDAAGVGTATHAIGDAAVRHVLDTVATLGPGARGRHRIEHIETVPDDQLPRFAELGVAASMQPPHTAYTRADHSDAWSRRLGPERAGRAWRIRELREAGAYVALGSDWPIAHHDARQVLALAQEPRGAARRGGGLSALMALEGVTSHAAAAAGEADVAGRIAPGHRADLTAFAADPLTTPAGELPGTPIALTVVGGSVRHRAV
>NZ_CP014485.1|WP_003947735.1|5535122_5535536_-|hypothetical-protein
MTKDHDDGRPDPAHRRPGEMSDTAVEALGALSKALETTERARGHLYSFHQLTGTADFQLDEAVRLLREAGHAEEAERVRTELVGRNVTPGHWTFQLVEEYDDGYYRPFAALEAELTDRLAGGRRHLHEAELKRRRRS
>NZ_CP014485.1|WP_061405042.1|5535661_5536630_-|phosphatase-PAP2-family-protein
MGPAGRSTRPAGPLGRLRTPRRPRIWFEILLIAVSYWVYSLIRNAVPEQKAQAMANADWIWEAEQRLGIAVEHGVNHAVNSVTWLIVGMNYYYATLHFVVTLGVLVWLYRRHPGRYAAARTVLFATTAVALVGYYLYPLAPPRLMNGQHFIDTVLVHQTWGSMASGDLKHMSNQYAAMPSMHIGWSLWCGLTIFALASVPWAKVLGLLYPALTLVVIVATANHFWLDAVGGLACLLFGYLVARLCYGALPKGLPQQVPDDRREATAPPAAAPTPPAPGPARSTEPPPAEEHPVPSPTGPGPRGATALTRASPEPSPAPAPES
>NZ_CP014485.1|WP_008409232.1|5536758_5537832_-|LacI-family-DNA-binding-transcriptional-regulator
MTARLADIAAQAGVSEATVSRVLNGKQGVAAATRESVLAALDVLGYERPVRLRRRSAGLVGLITPELENPIFPALAQVIGQALTRQGYTPVLATQTPGGSTEDELTEMLVDRGVSGIIFVSGLHADTTADMTRYDRLRGQGVPFVLIDGFTDQVRAPFISPDDRAAMRLAVTHLASLGHTRIGLALGPKRFVPVVRKTEGFTRALHDTFGIDAAEAGREFVRHSLYTLEGGQAAADSLLDGGCTAVVCASDMMALGAIRAVRRRGLDVPADVSVVGFDDSPLIAFTDPPLTTVRKPVTAMGQAAVRALLEEIGGTPAPPSEFVFMPELVVRGSTASAPPPDAPGVGEVPQREIVRKA
>NZ_CP014485.1|WP_026235343.1|5538160_5539444_+|extracellular-solute-binding-protein
MRRGIAATALVASLALAATACGGDTTDESGAKGGKSGGELAGTVTWWDTSTVGSEDKVFKALAEGFEKEHPKVKVNYVNVPFADAQNKFKNAASSGSGAPDVIRSEVAWTPDFASLGYLAPLDGTAALDKEDDYLKQAAASTKYDGKTFGVPQVIDSVGIFYNKKLLKEAGVEVPKTLDELTEAAKAIKSKTGKPALYLRGDDAYWFLSFLYGEGGDMINTKDKSVTIDDKPAIDAFKAVKELVDSKVAVTDATNGWDNMQKAIKDGEVAMAINGPWAVTDTLAGDAFKDKANFGVAPVPAGSKTAGSPQGGHNYAVYAGSKNLDASYEFVKYMSSAKVQAEVTEKLSLLPTRASVYGEPKVAENEIVQFFKPVVETAVERPWVPEGGSLFAPLQTQYTKVLTGQATPEQAAKSTGDSYRKLLKDYK
>NZ_CP014485.1|WP_003947731.1|5539527_5540538_+|sugar-ABC-transporter-permease
MAVHTGPSVAKAPGKATVPGPRRPARTRESGVRRALSTHWYAWTMVAPVVIVLAIIVGYPLGRGIWLSLTDATEANVERTIGVNHIPATYEFTGLQNYVDAFGDPVFLQRLVWTIVWTVACVSITYSLGLALATLLNRQVAGRGFYRMALVVPWAIPGFVSVFSWNFLYNEKHGLLNKILVGGGIDAVPWLNDPTIAKLSVIAVNVWLGVPFMMVALLGGLQSIPGDLYEAAEMDGASAWQRFRHITLPGLRPVSTTVILLSTIWTFNMFPVIFLLTRGGPGDATEILVTQAFRMTFVDSPRNFSTSATWGVIILLLLLVFAFFYRRVLKKQGEVW

Crispr_ID: NZ_CP014485_35

• CRISPR_ID: NZ_CP014485_35
• CRISPR_location: 5924770-5924875
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_35

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCTGT	CRISPRCasFinder

spacers of NZ_CP014485_35

>35.1|5924795|56|NZ_CP014485|CRISPRCasFinder
CTTTTGTGGCTGGGCTCCGCCCCGACCTGCCGCGCCTTGCCCCTGCGGGTCACCGA

CRISPR arrays and Neighbor proteins around NZ_CP014485_35

CRISPR arrays

The CRISPR arrays of NZ_CP014485_35

>merge|NZ_CP014485|35|5924770-5924875|CRISPRCasFinder
TGCCCTCAAGCGCCGGCCGGGCTGTCTTTTGTGGCTGGGCTCCGCCCCGACCTGCCGCGCCTTGCCCCTGCGGGTCACCGACGGCCTCAAACGCCGACCAGGCTCC

>NZ_CP014485|35|28|5924770-5924875|CRISPRCasFinder
TGCCCTCAAGCGCCGGCCGGGCTGT	CTTTTGTGGCTGGGCTCCGCCCCGACCTGCCGCGCCTTGCCCCTGCGGGTCACCGA
CGGCCTCAAACGCCGACCAGGCTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_003947406.1|5923575_5924709_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|225176
NZ_CP014485.1|WP_003947398.1|5932653_5932845_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_030308431.1|5913747_5915142_-|cobyrinate-a,c-diamide-synthase	unknown	unknown	gnl|CDD|234896
NZ_CP014485.1|WP_003947402.1|5929959_5930181_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008403786.1|5933182_5933848_+|hypothetical-protein	unknown	unknown	gnl|CDD|380217
NZ_CP014485.1|WP_059214066.1|5920932_5921154_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405107.1|5915734_5917849_-|putative-cobaltochelatase	unknown	unknown	gnl|CDD|274135
NZ_CP014485.1|WP_003947414.1|5913310_5913751_-|cobalamin-biosynthesis-protein	unknown	unknown	gnl|CDD|376648
NZ_CP014485.1|WP_008414241.1|5921185_5922466_-|inorganic-phosphate-transporter	unknown	unknown	gnl|CDD|376541
NZ_CP014485.1|WP_015508073.1|5919514_5920501_-|cobalamin-biosynthesis-protein	unknown	unknown	gnl|CDD|234919
NZ_CP014485.1|WP_037638617.1|5931295_5931916_-|hypothetical-protein	unknown	unknown	gnl|CDD|273565
NZ_CP014485.1|WP_003947412.1|5915135_5915735_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl|CDD|235662
NZ_CP014485.1|WP_015508074.1|5927241_5927658_-|glyoxalase	unknown	unknown	gnl|CDD|319943
NZ_CP014485.1|WP_059214067.1|5917949_5919518_-|cobyric-acid-synthase	unknown	unknown	gnl|CDD|234838
NZ_CP014485.1|WP_003947403.1|5927913_5929512_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223562
NZ_CP014485.1|WP_033240746.1|5925789_5927199_+|hypothetical-protein	unknown	unknown	gnl|CDD|235904
NZ_CP014485.1|WP_008417072.1|5930313_5931114_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|119339
NZ_CP014485.1|WP_003947407.1|5922778_5923501_+|class-II-aldolase/adducin-family-protein	unknown	unknown	gnl|CDD|376358
NZ_CP014485.1|WP_008403783.1|5932841_5933186_+|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl|CDD|377129
NZ_CP014485.1|WP_008403778.1|5932124_5932586_+|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl|CDD|377129

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_003947406.1|5923575_5924709_+|alpha/beta-hydrolase	gnl|CDD|225176	COG2267, PldB, Lysophospholipase [Lipid metabolism].	2.62787e-07
NZ_CP014485.1|WP_030308431.1|5913747_5915142_-|cobyrinate-a,c-diamide-synthase	gnl|CDD|234896	PRK01077, PRK01077, cobyrinate a,c-diamide synthase.	0
NZ_CP014485.1|WP_015508074.1|5927241_5927658_-|glyoxalase	gnl|CDD|319943	cd08355, TioX_like, Micromonospora sp. TioX and similar proteins. Micromonospora sp. TioX is encoded by a gene of the thiocoraline biosynthetic gene cluster. Thiocoraline is a thiodepsipeptide with potent antitumor activity. TioX may be involved in thiocoraline resistance or secretion. TioX belongs to vicinal oxygen chelate (VOC) superfamily that is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.79326e-39
NZ_CP014485.1|WP_033240746.1|5925789_5927199_+|hypothetical-protein	gnl|CDD|235904	PRK06995, flhF, flagellar biosynthesis protein FlhF.	0.00113447
NZ_CP014485.1|WP_003947414.1|5913310_5913751_-|cobalamin-biosynthesis-protein	gnl|CDD|376648	pfam01890, CbiG_C, Cobalamin synthesis G C-terminus. Members of this family are involved in cobalamin synthesis. The protein encoded by Synechocystis sp.cbiH represents a fusion between cbiH and cbiG. As other multi-functional proteins involved in cobalamin biosynthesis catalyze adjacent steps in the pathway, including CysG, CobL (CbiET), CobIJ and CobA-HemD, it is therefore possible that CbiG catalyzes a reaction step adjacent to CbiH. In the anaerobic pathway such a step could be the formation of a gamma lactone, which is thought to help to mediate the anaerobic ring contraction process. Within the cobalamin synthesis pathway CbiG catalyzes the both the opening of the lactone ring and the extrusion of the two-carbon fragment of cobalt-precorrin-5A from C-20 and its associated methyl group (deacylation) to give cobalt-precorrin-5B. This family is the C-terminal region, and the mid- and N-termival parts are conserved independently in other families.	1.0722e-28
NZ_CP014485.1|WP_008414241.1|5921185_5922466_-|inorganic-phosphate-transporter	gnl|CDD|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	4.03107e-97
NZ_CP014485.1|WP_015508073.1|5919514_5920501_-|cobalamin-biosynthesis-protein	gnl|CDD|234919	PRK01209, cobD, cobalamin biosynthesis protein.	2.01962e-110
NZ_CP014485.1|WP_037638617.1|5931295_5931916_-|hypothetical-protein	gnl|CDD|273565	TIGR01347, sucB, 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component). This model describes the TCA cycle 2-oxoglutarate system E2 component, dihydrolipoamide succinyltransferase. It is closely related to the pyruvate dehydrogenase E2 component, dihydrolipoamide acetyltransferase. The seed for this model includes mitochondrial and Gram-negative bacterial forms. Mycobacterial candidates are highly derived, differ in having and extra copy of the lipoyl-binding domain at the N-terminus. They score below the trusted cutoff, but above the noise cutoff and above all examples of dihydrolipoamide acetyltransferase. [Energy metabolism, TCA cycle].	0.00192501
NZ_CP014485.1|WP_003947412.1|5915135_5915735_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl|CDD|235662	PRK05986, PRK05986, cob(I)yrinic acid a,c-diamide adenosyltransferase.	1.34397e-114
NZ_CP014485.1|WP_008403786.1|5933182_5933848_+|hypothetical-protein	gnl|CDD|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	1.28152e-05
NZ_CP014485.1|WP_059214067.1|5917949_5919518_-|cobyric-acid-synthase	gnl|CDD|234838	PRK00784, PRK00784, cobyric acid synthase.	0
NZ_CP014485.1|WP_003947403.1|5927913_5929512_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	4.60824e-178
NZ_CP014485.1|WP_008417072.1|5930313_5931114_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	2.12777e-55
NZ_CP014485.1|WP_061405107.1|5915734_5917849_-|putative-cobaltochelatase	gnl|CDD|274135	TIGR02442, Uncharacterized_protein_Rv2850c/MT2916, cobaltochelatase subunit. Cobaltochelatase is responsible for the insertion of cobalt into the corrin ring of coenzyme B12 during its biosynthesis. Two versions have been well described. CbiK/CbiX is a monomeric, anaerobic version which acts early in the biosynthesis (pfam06180). CobNST is a trimeric, ATP-dependent, aerobic version which acts late in the biosynthesis (TIGR02257/TIGR01650/TIGR01651). A number of genomes (actinobacteria, cyanobacteria, betaproteobacteria and pseudomonads) which apparently biosynthesize B12, encode a cobN gene but are demonstrably lacking cobS and cobT. These genomes do, however contain a homolog (modelled here) of the magnesium chelatase subunits BchI/BchD family. Aside from the cyanobacteria (which have a separate magnesium chelatase trimer), these species do not make chlorins, so do not have any use for a magnesium chelatase. Furthermore, in nearly all cases the members of this family are proximal to either CobN itself or other genes involved in cobalt transport or B12 biosynthesis.	0
NZ_CP014485.1|WP_003947407.1|5922778_5923501_+|class-II-aldolase/adducin-family-protein	gnl|CDD|376358	pfam00596, Aldolase_II, Class II Aldolase and Adducin N-terminal domain. This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.	1.33377e-58
NZ_CP014485.1|WP_008403783.1|5932841_5933186_+|Asp23/Gls24-family-envelope-stress-response-protein	gnl|CDD|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	2.22284e-08
NZ_CP014485.1|WP_008403778.1|5932124_5932586_+|Asp23/Gls24-family-envelope-stress-response-protein	gnl|CDD|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	1.48351e-35

Protein sequences

>NZ_CP014485.1|WP_003947406.1|5923575_5924709_+|alpha/beta-hydrolase
MRIARTTALAVTAAVGAGAAAVAAGRYASDAALRLPAGHRLPTEPKLTVHRAEAGRITLTRDLASLRPGRYGLTGRDFHAAVGPVLDRADGEVAADTVVRRLERVFDGTPDTGDRAWLTPQLYSGDPATALGLSYAEVEIPGELGVLPGWVVPGDRRTWVLAVHGLAGTIEHPMVVMDQLHRLGLPVLSLAYRGDRGAPRSPDGLNHLGDTEWRDVDAALRFAVANGAARVILYGWSTGATMALFTAARSSLRGRIGGLVLDSPVLGRARTVRALAAARHIPNAFLPLAVRAAEGRTGLSDDRLPHIGGPEGIRVPTLLLHGPDDEIASYDYSLALARSRPDLITLHTVPDAPHAAMWNASPSTYDESLRRFLTPLL
>NZ_CP014485.1|WP_003947407.1|5922778_5923501_+|class-II-aldolase/adducin-family-protein
MEKNRAHPGRPWRPQEDQAVAHAWHDLVETARATVRDGLVVGTSGNVSVRVTPDRPAGGTGDLVLITPTGVPYDRLGPEDTVAVGLDGRQVLGTLKPTSELPLHLAVYRTGTARAVVHTHAPHATAVSTLVDTLPPVHYMAAALGGPVRTAPYALYGSQELAGHLVEALRDRTACLLRNHGTVTTGDTLTQALDRTAQLEWMCRVWLLARSVPGHTPSLLDAGQLDAAAERLRGYGQPGG
>NZ_CP014485.1|WP_008414241.1|5921185_5922466_-|inorganic-phosphate-transporter
MEHITLLLGIVIVTALVFDFTNGFHDTANAMATTISTGAMRPKAAVAMSAVLNLVGAFLSVEVAKTISGGLINEDGLKTEVIFAALVGAILWNLLTWLVGLPSSSSHALFGGLIGAAVMSAGWSSVNGGTVVTKVLLPALAAPLVAGLAAMLATRLTFRINRNVDEKSTAKGYRAGQIASAGLVSLAHGTNDAQKTMGVITLALVTGGVLAPGSNPPMWVIVSAGVAIALGTYLGGWRIIRTMGKGLTDLTPPQGFAAQTSAATVILASSHLGFSLSTTQSCSGAVMGAGLGRKGGVVRWSTATRMFVAWGLTLPAAALVGAAAELLTKQGDWGVAATAVLLVGGSFAIWLRSRRSPVTHDNVNDVEPVQDEPSGIVTQAMASVAPPPTGAAVASEEADGSPLGSIPAQPGHSSATTEPAARPAKV
>NZ_CP014485.1|WP_059214066.1|5920932_5921154_-|hypothetical-protein
MDIDWAALGSVFGVSLVVTVALVGFFTLGIVGLSKASSGTQGGGSGVAAKAGGYLCFALCAAAVAYGIYIIVA
>NZ_CP014485.1|WP_015508073.1|5919514_5920501_-|cobalamin-biosynthesis-protein
MDRADRVFAYGATAGLLADALFADPRRGHPVALFGRAASAVERRLFHDHRGWGALHTALCAGGVTAGAALAARAVRPHPCAAVALTAATTWAVVGGTSLVREARLIGAALEAGDVAEARRLLPRLCGRDPQALDADALARAVVESVAENTSDAVVGALVWGALAGVPGLAGFRAVNTLDAMVGHKSPRLRRFGWASARLDDVVGHPGARLTAALAVLAGPDPRGALRAWRADAHRHPSPNAGPVEAAFAGALGVRLGGTLAYGGRTEHRPVLGGSGRAVRPGDIERAARLSRRVGALALVAGAGARLAAGAIRGRARRAATGQGGAGA
>NZ_CP014485.1|WP_059214067.1|5917949_5919518_-|cobyric-acid-synthase
MSGGVLIAGTTSDAGKSVLTAGICRWLARRGVKVAPFKGQNMSLNSFVTREGAEIGRAQAMQAQAARVEPTALMNPVLLKPGGDRSSQVVLLGKPVGELSAQGFFGSVRPGEPARAVSGGRREALLEPVLACLAELRATHDVVVCEGAGSPAEINLRRTDIVNMGVARAAKLPVLVVGDIDRGGVFASFFGTTALLAPEDQALVAGYVVNKFRGDVELLKPGIEMLRSITGRHTFGVLPYAEGLGIDEEDGLRISLRGAVRESVVAPPVGADVLRVAVCAVPLMSNFTDVDALAAEPGVVVRFVDRPEELADADLVVVPGTRGTVRALAWLRERGLADALLRRVAEGRPVLGICGGYQLLGERIEDEVESRAGTVEGLGVLPVRVRFAVEKTLARPDGSALGEPVEGYEIHHGVAEVQGGEPVFTDADGRALDGCRTGAVWGTHWHGSLESDGYRRAFLTEVARAAGRRFVPAPGTSFGQLREEQLDRLGDLIEEHADTDALLRLIEQGAPPGLPFLPPGAP
>NZ_CP014485.1|WP_061405107.1|5915734_5917849_-|putative-cobaltochelatase
MSTSSRYPFTAIVGQDDLRLALLLNAVSPAVGGVLVRGEKGTAKSTAVRALAALLPPVRTVEGCRFSCDPAAPDPGCPDGPHPAVGPGGERAARMVELPVGASEDRLVGALDIERALAEGVKAFEPGLLADAHRGILYVDEVNLLHDHLIDLLLDAAAMGASYVEREGVSVRHAARFLLVGTMNPEEGELRPQLLDRFGLTVEVAASREPDQRVEVVRRRLAFEDDPAAFAGRWSGEEAGLRERVAAARALLPRVRLGDGALRRIAAVCAAFEVDGMRGDLVMARTATALAAWAGRTEVAVEDVRQAALLALPHRRRRNPFDAPGLDEEKLDEVLRDAAADDPEDEPPTPPEEPGGGDDDGPGPDGGGGGRPDPGDGAGDGSGGLPPQRTEDSGAPAPEDAPEALTGAEPGESGGGTPRPASAEQRAVAAGEPFRTKVLSVPGLGAGAAGRRSRARTEHGRTTGATRPEGALTKLHLTATVRAAAPHQRARGRSGPGLVVRRDDLRQATREGREGNLVLFVVDASGSMAARRRMGAVKGAVLSLLLDAYQRRDKVGLVTFRGREAEVALPPTSSVDAAAARLQALPTGGRTPLAAGLLKAHDVLRVERLRDATRRPLLVVVTDGRATGGPEPVALAGRAARLHAAEATASVVVDCETGPVRLGLAGELARELRGTAVTLDELRAEALTGLVKDVTDHHRARRAA
>NZ_CP014485.1|WP_003947412.1|5915135_5915735_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MPQGQPSVVPEDGLTTRQRRNRPLVAVHTGPGKGKSTAAFGLALRAWNQGWPIGVFQFVKSAKWKVGEENALKTLGASGEGGRVDWHKMGEGWSWVQRDDQQDNEAKAREGWEQVKRDLAAETYRLYVLDEFAYPLHWGWIDTAEVIEVLRNRPGNQHVVITGRNAPAELVDFADLVTEMTKVKHPMDAGQKGQRGIEW
>NZ_CP014485.1|WP_030308431.1|5913747_5915142_-|cobyrinate-a,c-diamide-synthase
MVSTLRIPRLVVAAPSSGSGKTTVATGLMAAFTGRGLTVSPHKAGPDYIDPGYHALATGRPGRNLDAYLCGTELLGPLFAHGAAGADLAVVEGVMGLYDGAAGQGELASTAQLAKALRAPVVLVVDGSSQSRSVAALVHGFASWDPEVRIGGVILNKVGSDRHEELLREALDEAGVDVLGVLRRTPQAATPSRHLGLVPVAEREPDAVAAVAAMAEQVRAGCDLDALWALARSAPPLTGAPWDPAGALAGSGTPPPSGPRPVVAVAGGAAFTFSYAEHAELLTAAGAEVVPFDPLRDEHLPESTGALVIGGGFPEVYAPELSANAALRAEVAALAAAGAPVAAECAGLLYLARELDGAPMCGVLDASARMTERLTLGYRDAVAVGDSVLAPAGTRVSGHEFHRTRLAPGAGTAPAWGVVRPGPPRTEGFVQGGVHASYLHVHWAALPTAAARLVARAVRPGAPV
>NZ_CP014485.1|WP_003947414.1|5913310_5913751_-|cobalamin-biosynthesis-protein
MTASPAGAGLVVGVGACRDAPAEAVYGLVREVLAELGPAAGPLLELATVEAKATEPGIVEAARLLGVRLRSWAPGVLAAVETPHSSPTALAALGVASVAEAAALAGGGELLVPKRKQGGPGPAVATCAVARRGPAAGVPGDGTTTE
>NZ_CP014485.1|WP_033240746.1|5925789_5927199_+|hypothetical-protein
MTSRIPRDSRLRIVRPRPLAAAPAAVAERRARRPAPRPPEGTPPRARLAAMAREGLADAVRVARWAEAALPRGGPAARPAAPADGEGTLSEATAAHAAGELGLTPAKVRADWDTARLAGLVEVHGGVARPGWRLRAWDRDDSAVLRGWVALFDAWSLVHPGPDELTPAAGAEVIEAVPQLLTLLQLSDGPVPVTQLLDLLEQRVEELRTQRCEIPYGPRTEPAAEPAEDVPLATLLDWALHGLAAVGALTYADGHATLTPLGSWAVWVRLEQICVAAQSPAGNIEQPAEEMLRGCARLRPQSARSEYRAWLAARPVGSAVAELLEAARGEDAMVRSLAFEALRVVGAPAEAEVRAAAEDALLRPYALLWLAEHDGTDPEDAPLVLSRQEATWLWVDTAAAVADHGEAPLLVRHLEAAVQPTVPALLADVRAVGHPRTVQVLVALAAAHPDPALAKAVRRAAFQVHTGGA
>NZ_CP014485.1|WP_015508074.1|5927241_5927658_-|glyoxalase
MAATASGPPTVFPTVLYADARAAVRTLTEAFGFAPAAVHETADGRIAHAELSLGNGAVMIGPKGTGSAYDRAMAEGGPVGVYVVVADVDAHHARAAAHEGVEILVPPTDQEYGSRDYMARDAEGNIWSFGTYGPELPA
>NZ_CP014485.1|WP_003947403.1|5927913_5929512_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MITASGVELRAGARVLIESATFRIAKGDRIGLVGRNGAGKTTLTKCLAGQGQPAAGTITSSGEVGYLPQDPRTGDLDVLARDRILSARGLDTLIKKMRENEQRMATGQGATREKAMRKYERLETEFLTKGGYAAEAEAATIAAALNLPDRVLGQPLHTLSGGQRRRIELARILFSDADVLLLDEPTNHLDADSIAWLRDYLKTYRGGFIVISHDVDLVETVVNKVFYLDANRAQIDIYNMGWKLYQQQREADEKRRRRERQNAEKKAATLNAQADKMRAKATKTVAAQNMARRAERLLSGLEAERVSDKVAKLRFPEPAPCGKTPLTAEGLSKSYGSLEIFTDVSLAIDKGSRVVILGLNGAGKTTLLRLLAGTEKPDTGSVVEGHGLKLGYYAQEHETLDPDRTVLENMRSAAPDLDLVEVRKTLGSFLFSGDDVDKPAGVLSGGEKTRLALATLVVSSANVLLLDEPTNNLDPASREEILGALKTYKGAVVLVTHDEGAVDALQPERIILLPDGVEDLWGADYLDLVTLA
>NZ_CP014485.1|WP_003947402.1|5929959_5930181_+|hypothetical-protein
MAETLKKGSRVTGAARDKLAADLKRKYDDGASIRALAEETGRSYGFVHRMLSESGVTLRGRGGATRGKKPSSD
>NZ_CP014485.1|WP_008417072.1|5930313_5931114_+|enoyl-CoA-hydratase/isomerase-family-protein
MAATDPATPLLDQDGVRLTVDGATATVTLTNPAKRNAQSPALWRSLAEAGRLLPGSVRIAVIRGEGKSFSAGLDRQAFTPEGFEGEPSFVDMGKGPAEEMDAIIASYQEAFTWWRRSDLITIAAVQGHAIGAGFQLALACDLRVVAEDVQFAMRETSLGLVPDLTGTQPLVHLVGYARALEICATGRFVHAEEAERTGLANLVVPAEQLDAAVADLAAALLAAPRDAVVETKVLLQGAVGRGLDEQRAAERAAQGRRLRDLVGQGD
>NZ_CP014485.1|WP_037638617.1|5931295_5931916_-|hypothetical-protein
MLRQAADTVPGARLGALRIGPVDGAPTEEPGVPPPPSALWPGPLRIGAEFAATRLEPFPALADRLRATLSEAATHRLGLHVTEVDLRITGVDRPGEASEAESPASPAAPGSSPAESRPPHEDTPEARAATAALAVPGVARLAGAFGGRTGAVRMDHPAPGRPGHVRLELAVSPGHRPLEVARAVRQAVSEALPDRPSVAVLVTEVG
>NZ_CP014485.1|WP_008403778.1|5932124_5932586_+|Asp23/Gls24-family-envelope-stress-response-protein
MTEPTQRESQGELGGRRSHGGPGTRGKTTIADGVVEKIAGLAARDVDGVHAMGSGISRTLGAMRDRVPGGGKSVTRGVSAEVGEVQTALDLEIVVEYGVSIADVARSVRENVVNAVERMTGLEVVEVNIAVSDVKLPDEDDDQDDGGDGRNLQ
>NZ_CP014485.1|WP_003947398.1|5932653_5932845_+|hypothetical-protein
MSMALIGLVAGLALGFAGYFGGFGAFVLVAALGAVGFLAGRIADGDLEPGDFFRPRGRDSGRR
>NZ_CP014485.1|WP_008403783.1|5932841_5933186_+|Asp23/Gls24-family-envelope-stress-response-protein
MTPVTSGPVAPAERGETRIADRVVARIAGQAAREALRGNQRDADPPRATVSIHQDHARVRVSVELGYPTDIGRQCGAVRRRVTERVEGLTGMTVPEVAVQVEKLRVAGKQGRAR
>NZ_CP014485.1|WP_008403786.1|5933182_5933848_+|hypothetical-protein
MSETPEQNGATRAGSGGVLEKDPRVLDPTPPERGPGLAPGGRAHRFWSARRIPAALTALVLLGASGLLLYDVVAVRAGHRAMAWRRTLARELASRPLDDTWTLVGAGVAAALGLWLLLLALTPGRRRLLQMNKVHPDVRAVLHRKAAALVLRDRAMEVPGVQSAKVRLKRRKAKVRAVAHFRDVDEVRTDLRSASGRAVEDLGLARPPKVSVKVVRPRRKG

Crispr_ID: NZ_CP014485_36

• CRISPR_ID: NZ_CP014485_36
• CRISPR_location: 6021698-6021788
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP014485_36

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCT	CRISPRCasFinder

spacers of NZ_CP014485_36

>36.1|6021721|45|NZ_CP014485|CRISPRCasFinder
GTGAAGGGTGGGGGCTGAGCTTGCCGCCCGCCTTCGCGTCACCGA

CRISPR arrays and Neighbor proteins around NZ_CP014485_36

CRISPR arrays

The CRISPR arrays of NZ_CP014485_36

>merge|NZ_CP014485|36|6021698-6021788|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGTGAAGGGTGGGGGCTGAGCTTGCCGCCCGCCTTCGCGTCACCGATGGCCTCAAGCGCCGGCCGGGCT

>NZ_CP014485|36|29|6021698-6021788|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCT	GTGAAGGGTGGGGGCTGAGCTTGCCGCCCGCCTTCGCGTCACCGA
TGGCCTCAAGCGCCGGCCGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061405129.1|6018793_6019333_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|369056
NZ_CP014485.1|WP_031177989.1|6012290_6013022_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|313370
NZ_CP014485.1|WP_059212920.1|6023536_6024592_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486
NZ_CP014485.1|WP_037843783.1|6028765_6029878_+|hypothetical-protein	unknown	unknown	gnl|CDD|274673
NZ_CP014485.1|WP_003947314.1|6027969_6028413_-|cell-division-protein-SepF	unknown	unknown	gnl|CDD|377370
NZ_CP014485.1|WP_061405133.1|6024845_6026009_-|glycosyltransferase-family-39-protein	unknown	unknown	gnl|CDD|227829
NZ_CP014485.1|WP_061405132.1|6021959_6022970_+|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP014485.1|WP_003947321.1|6017813_6018584_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_030309498.1|6031487_6032402_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP014485.1|WP_061405131.1|6020771_6021683_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405134.1|6032398_6034300_+|FAD/NAD(P)-binding-protein	unknown	unknown	gnl|CDD|379196
NZ_CP014485.1|WP_008409584.1|6023226_6023442_+|hypothetical-protein	unknown	unknown	gnl|CDD|288556
NZ_CP014485.1|WP_003947325.1|6013127_6014213_+|prephenate-dehydrogenase	unknown	unknown	gnl|CDD|235824
NZ_CP014485.1|WP_008403414.1|6014349_6015051_+|(d)CMP-kinase	unknown	unknown	gnl|CDD|234579
NZ_CP014485.1|WP_030770087.1|6029894_6030881_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270225
NZ_CP014485.1|WP_061405130.1|6019494_6020775_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340847
NZ_CP014485.1|WP_030310408.1|6017361_6017703_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_003947322.1|6015797_6017261_+|ribosome-biogenesis-GTPase-Der	unknown	unknown	gnl|CDD|179525
NZ_CP014485.1|WP_008403410.1|6015047_6015701_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_CP014485.1|WP_003947315.1|6026238_6027960_+|MFS-transporter	unknown	unknown	gnl|CDD|184957

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP014485.1|WP_061405132.1|6021959_6022970_+|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	2e-55	183.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_061405129.1|6018793_6019333_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|369056	pfam06737, Transglycosylas, Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues.	1.00269e-27
NZ_CP014485.1|WP_031177989.1|6012290_6013022_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|313370	pfam10127, Nuc-transf, Predicted nucleotidyltransferase. Members of this family of bacterial proteins catalyze the transfer of nucleotide residues from nucleoside diphosphates or triphosphates into dimer or polymer forms.	8.79917e-33
NZ_CP014485.1|WP_059212920.1|6023536_6024592_-|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.29314e-30
NZ_CP014485.1|WP_003947314.1|6027969_6028413_-|cell-division-protein-SepF	gnl|CDD|377370	pfam04472, SepF, Cell division protein SepF. SepF accumulates at the cell division site in an FtsZ-dependent manner and is required for proper septum formation. Mutants are viable but the formation of the septum is much slower and occurs with a very abnormal morphology. This family also includes archaeal related proteins of unknown function.	2.12399e-26
NZ_CP014485.1|WP_061405133.1|6024845_6026009_-|glycosyltransferase-family-39-protein	gnl|CDD|227829	COG5542, COG5542, Predicted integral membrane protein [Function unknown].	1.68508e-07
NZ_CP014485.1|WP_061405132.1|6021959_6022970_+|YafY-family-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	4.76619e-50
NZ_CP014485.1|WP_030309498.1|6031487_6032402_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	6.54371e-74
NZ_CP014485.1|WP_037843783.1|6028765_6029878_+|hypothetical-protein	gnl|CDD|274673	TIGR03601, B_an_ocin, bacteriocin, heterocycloanthracin/sonorensin family. Numerous bacteria encode systems for producing bacteriocins by extensive modification of ribosomally produced precursors. Members of the TOMM class (thiazole/oxazole-modified microcins) are recognizable by association with cyclodehydratase (and often dehydrogenase) maturation proteins. This family consists of a special subclass, the heterocycloanthracin family, that share a homologous leader peptide region and then a repeat region with Cys as every third residue. In Bacillus anthracis and Bacillus cereus, the RiPP (ribosomally translated and post-translationally modified natural product) precursor is encoded far from its maturase genes, and every strain has the system. In other species (e.g. B. licheniformis, B. sorenensis), precursor and maturase genes are close together. Sonorensin, from B. sonorensis MT93, was shown to have broad spectrum antimicrobial activity, affecting Gram-positive and Gram-negative bacteria. [Cellular processes, Toxin production and resistance].	0.00304331
NZ_CP014485.1|WP_061405134.1|6032398_6034300_+|FAD/NAD(P)-binding-protein	gnl|CDD|379196	pfam13454, NAD_binding_9, FAD-NAD(P)-binding.	2.0867e-38
NZ_CP014485.1|WP_008409584.1|6023226_6023442_+|hypothetical-protein	gnl|CDD|288556	pfam11720, Inhibitor_I78, Peptidase inhibitor I78 family. This family includes Aspergillus elastase inhibitor and belongs to MEROPS peptidase inhibitor family I78.	0.00339193
NZ_CP014485.1|WP_003947325.1|6013127_6014213_+|prephenate-dehydrogenase	gnl|CDD|235824	PRK06545, PRK06545, prephenate dehydrogenase; Validated.	4.92654e-125
NZ_CP014485.1|WP_008403414.1|6014349_6015051_+|(d)CMP-kinase	gnl|CDD|234579	PRK00023, cmk, (d)CMP kinase.	2.59794e-98
NZ_CP014485.1|WP_030770087.1|6029894_6030881_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.57935e-67
NZ_CP014485.1|WP_061405130.1|6019494_6020775_+|glycosyltransferase-family-4-protein	gnl|CDD|340847	cd03820, GT4_AmsD-like, amylovoran biosynthesis glycosyltransferase AmsD and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.	2.24054e-104
NZ_CP014485.1|WP_003947322.1|6015797_6017261_+|ribosome-biogenesis-GTPase-Der	gnl|CDD|179525	PRK03003, PRK03003, GTP-binding protein Der; Reviewed.	0
NZ_CP014485.1|WP_008403410.1|6015047_6015701_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	1.48578e-34
NZ_CP014485.1|WP_003947315.1|6026238_6027960_+|MFS-transporter	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	2.47349e-115

Protein sequences

>NZ_CP014485.1|WP_061405131.1|6020771_6021683_+|hypothetical-protein
MTALLPRPSQGSTGPGPAGGPPRADCVADTAGGLTFDLAGLDGLADRATGGAALLLRPRERGADTVPLPLTPAGGGRLRAALPRTVPLPEGHWDAWLRLPGSPDRRLAPGAHHLGPLTAARAADAAAGRVVARLPYATRGGRLSLRSWLRAPHAETLGLSAGAGRLTVTGRLYGAAVTAHAYGEIRAVDAPGPLCRVPVTPTPEPGHPPTEGTPFTLTLPHPDLAADGRPRTWSLWLRPAGATGPEARLARLLGPGGVTTAPTPHPPLALPGPRGPLHAAPLYTPGHDLTLRLSPALPPPRRG
>NZ_CP014485.1|WP_061405130.1|6019494_6020775_+|glycosyltransferase-family-4-protein
MRISFLIHNAYGIGGTVRATHNLAAGLAEQHEVEIVSVFRHREKPFLDHHPRVTLRHLVDTRTGTTGYEGDHPEHAIAAEDFPREDRRYHAYSMLTDRRIRAHLGASGADVVVTTRPGLTHHLARQGAAGAVRVGQEHLGLDAHTPALRSRLRTVYPRLDALTTATEADARAHRGRLRLPGVHVAVLPNAVPAPAGPPADPAARRIVAAGRLVPVKRYELLIRAFARVHALHPEWSLDICGDGERRAALAELVDELGLTGHVRLRGAVNPMEEAWTGGSVAAVTSRWESFGMTVVEAMRCGVPVVAVDCPHGPREIITDGVDGLLVRSAGPDALAEALLSLVGDENLRLSMGRAALASAARYSPAAVAERCSDLFTSLAARRGRSGAAARLRGSAHRARGAALSTAFALRDTGRAVGAALAPGGAT
>NZ_CP014485.1|WP_061405129.1|6018793_6019333_+|LysM-peptidoglycan-binding-domain-containing-protein
MPHLLAAAVAALALLAPGHGHAHRADPAGTPDCRSAPWPWGCVADCESDGRWDADTGNGYYGGLQFAPATWRDFGGERYAPAAHLATAEEQIAVGRDVLRVQGWEAWPSCAKRYGLAGRAHTVEPGDTLTSVAARFRVPGGVEGLYRLNEETVGPDPDLLAVGVLLALPPGSGSGRAGG
>NZ_CP014485.1|WP_003947321.1|6017813_6018584_-|hypothetical-protein
MPRMLDVSDDVRAEIGDAEAERLLAGENTPGHYDCTSCRTPGDSEQERTSTVLFVGDETAVLAFAHATCLPSQIVKVAEEQLQGAVRSINADGAGEPAPEQAVLGVTSGLVLIDGELHPALVVEPTGPIVRPGSGGTEDAFLDLLAEQGFVPCPTVEQVPPVLHGWSVLLAVGQLHAVLQPGPEPGAPVAWWQAHQPLQVADSWRAAANKSQTVLVYAAPAGSIGQQPREDLLRDALDRAAAQGRLVAAAMPLAGT
>NZ_CP014485.1|WP_030310408.1|6017361_6017703_-|hypothetical-protein
MHAYDPSRSRPLPPSSIPSMRPAQDLTDGRSPTPIFDALCAEYRRSFRALPGDRSGEEDLRFHAFGGPQSFRRPPQDPFARSPEERATGSWTPPSRRHAAPALPPAPPRWERQ
>NZ_CP014485.1|WP_003947322.1|6015797_6017261_+|ribosome-biogenesis-GTPase-Der
MNDHHISDDEHGELGEAEYAQFMELAAEEGFDIDDVEDAIEEAGHGPLPVLAVVGRPNVGKSTLVNRIIGRREAVVEDKPGVTRDRVTYEAEWAGRRFKLVDTGGWEQDVLGIDASVAAQAEYAIDAADAVVFVVDATVGATDTDAAVVRLLRKAGKPVVLCANKVDGPSAEADAAMLWSLGLGEPHPVSALHGRGTGDMLDAVIEALPDAPAQTFGGAAPGGPRRIALIGRPNVGKSSLLNKVAREDRVVVNELAGTTRDPVDELIELGGVTWKFVDTAGIRKRVHLQQGADYYASLRTAAAVEKAEVAVILIDAGESISVQDQRIVTMAVDSGRAIVVAYNKWDTLDEERRYYLEREIETELAQIAWAPRVNVSAATGRHMERLVPAIETALAGWETRVPTGRLNAFLGELVSSHPHPVRGGKQPRILFGTQAGTKPPRFVLFASGFIEHGYRRFVERRLREEFGFEGTPIKISVRVREKRGRKK
>NZ_CP014485.1|WP_008403410.1|6015047_6015701_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MTADTLPSERGAAVGRGIGIGLMYGLWRPRVLGAWRVPSAGPVILAVNHSHMIDGPMLMGTAPRPVHFLIKKEAFVGPLDPFLKGIGQLKVDRDTTDRAAVTDALGVLKAGGVLGIFPEGTRGEGDFASLRAGLAYFAVRSGAQVVPVAVLGGADRPGRLVKALPPLRSRVDVVFGDPFEAGDGSGRRTRKALDEATVRIQAELRAHLTNARRLTGR
>NZ_CP014485.1|WP_008403414.1|6014349_6015051_+|(d)CMP-kinase
METAPRTVPAIIVAIDGPSGTGKSSTSKAVATALGLRYLDTGAQYRAITWWMVENGIDTADAEAVADAAAKPEIVSGTDPLAPTITVDGIDVSGPIRTQEVTSKVSAVSAVPRVRTLITELQRSIAAGAEGGILVEGRDIGTTVLPDADLKVFLTASPEARAARRSGELKGKEATDLAATREALLRRDAADSGRKTSPLAKAEDAVEVDTSDLTLQQVIECVVTLVEEKRALR
>NZ_CP014485.1|WP_003947325.1|6013127_6014213_+|prephenate-dehydrogenase
MRTALVIGTGLIGTSIALTLAERGVAVYLADADPGQARTAAGLGAGSAEEPPGQVDLAVVAVPPAHVAATLADAMRSGRARAYLDVASVKGGPRRELAALGLDLSGYLGSHPMSGREQSGPLAATADLFEGRPWVLTPTPETDTEVLNLALELVSLCRGVPVVMDADAHDRAVALVSHMPHLVSGLVAARLEHAEDSAVRLCGQGIRDVTRIAASDPRMWIDILSANPGPVADLLGALAEDLEATVAALRALESGDGEKRRAGAEGVERILRRGNAGQIRVPGKHGTAPRAYETVAVLISDQPGELARIFADAGRAGVNIEDVRIEHATGQQAGLVQLMVEPAAVGPLRVGLAERGWSLRA
>NZ_CP014485.1|WP_031177989.1|6012290_6013022_-|nucleotidyltransferase-domain-containing-protein
MPVDGDGRTPWEAAGGELVLVEEHTIVSWVMGSRAFGLATEESDTDRRGVYVAPTPWFWGFSRPPTHLDGPQEERFSWELERFCSLALAANPNILECLHSPLVEFTDPRGEELLSLRDAFLSREVLRTFSRYVAGQRRKLEADVRTHGAPRWKHAMHLLRLQRSCRDLLRTGRLVVEVGEAREELLAVRRGEWSWDRVAAALAELDAACEEAALTTPLPAAPDRARVADFLYRIRRDSAAALG
>NZ_CP014485.1|WP_061405132.1|6021959_6022970_+|YafY-family-transcriptional-regulator
MLDTSARLLRLLSLLQAHRSWTGPQLADRLGVTARTVRRDVERLRELGYPVNAAPGTTGGYQLGAGAELPPLLLDDDEAVAVAVGLRTAAGGGVEGVGESSVRALAKLEQVLPSRLRRRVGALHAYTVPLLRDPGGPGVEPGVLTELAAVCRDAERLRFAYRDHAGNESRRTVEPHRLVCTERRWYLVAWDVDRADWRTFRADRITPRPPHGPRFTPREGPAGDLAAYVSEGLSTRVYPDRVVLRLLVPLAEAAGRISPSDGTLAAESADSCLLTAGATSLDVLVIHVLLLGLEFEVVEGDGVQEGLRAAHGLLGRALERGERKGERDAGAFPESE
>NZ_CP014485.1|WP_008409584.1|6023226_6023442_+|hypothetical-protein
MASLPTPPPDPQDDPAAYVGLTAEEAERQAGERGWTTVRTLQPGAMITMEFLVGRINFEVTDGRVTRGWKG
>NZ_CP014485.1|WP_059212920.1|6023536_6024592_-|phosphatase-PAP2-family-protein
MGTEPNLTRLDRLFARLDREQQRPEQLHVPRMSRHRIALFGATLAFYATIVVAVITTSWLVRLDWQLMFFRPYQQWPEIHPYLDYYVVLGQRGPTAVMVAAWLGWRSWRQHTLRPLLALGASLLLLNVTVGAAKIGMGRLGPHYATEIGANEMWQGGDIFPSGHTANAVVTWGILAYLAATPRARRHLSTLSAVVSLGVGLTTVYLGTHWLSDVLLGWAAGVLILLALPWFEPMINWAEARILATRDLLWARWGDRLPMPRPGAATPAGSASAQAAPPAPPSTSSAPAERLVVEPSAQQLRPGGNRPHLAQRPHAGRAERPSQPPSATRRPPHSGDRSQRGGPSPRPVAGG
>NZ_CP014485.1|WP_061405133.1|6024845_6026009_-|glycosyltransferase-family-39-protein
MTASDQIRPLSAPRAPDPGPPGPRRAGLALAVYAAVRLTGLAVLTAWSALAGNDAHRLLSRRWDSLWYARVAEQGYGWEVVLPDGAVHSNLAFFPLLPWLERLGSWLTPLAAPDVGLVVSALASLAAAWGIYAVAERLYGAVAGVTAVALWAVLPVGIVQSMAYSESLFTALAAWALYALLRERWIVAGLLASLAGLTRPVGMAVTAAVLLGVALAARRERRLTPAMAAGALFSPLGAGAYVVWVGARTGDPLFGYLSVQEGWGNGFDGGLAFARFIGSLLAGPGFWGGLGLVAGLALLAWLCARCVRQGQPAVLLVYAGIVVVLAVCASGYFGSKPRLLLPAFPLLLPLAVGLARWGAVRRGLLLAGVGLLSAGYAGFWLNGSGPP
>NZ_CP014485.1|WP_003947315.1|6026238_6027960_+|MFS-transporter
MTGTPRTAQPEGAEAPARRWMILVVLCASLLLVAVDATVLHVAIPAVSEDLRPGQVQLLWIVDSYPLVCASLLILFGTLGDRVGRRRILLLGYALFGIASALAAAAESAQLLIAARALLGVGGAMIMPATLSILRQVFPDRRERALAIGVWSAVAGIGAAGGPLLGGFLLEHFWWGAVFLINIPIMLVSLPVGRWLLPESTGDGQGPWDAVGALLAAGGLFGVVLGVKQAGSGEVSLLGTLVPLVLGAVLLVVFVRRQRGREHPLVDLALFARPAFGTSVGCIVLAMLALVGLELIAAQYLQLVLGLSPLETGLRLLPLTFAAMAAGLAGSRLLPRLGPRAMVGAGFTLTAVAVLVLTGMGDHDNPPLLIGGFVLLGLGLQTTLFSSYESMLSEAPKEEAGGAAAIGETSYQLGAGIGIALLGSVMNAAYGPGLRHVEGVPASAVADARHSLGEAYDVARELGGPAGAALRTAAKDSFVHGLHVTLVVSAGLLLLGALAALRLPRSMDPTPAEPAGPGPGSTDGAGTSVPGPRGTEDAEEAPRAEAPRPRTEKDPGRAAPADGHRTRDSALRG
>NZ_CP014485.1|WP_003947314.1|6027969_6028413_-|cell-division-protein-SepF
MGSVRKASAWLGLVDDNDERYYDGYADEATEGPEPGDAWVTDPRVQVASESAHEQGRRIGTVTPESFRDARRIGELFRDGVPVIINLTAMDPGDAKRVVDFAAGLIFGLRGSIERIATRVFLLSPPDTEIVDGGAAHRTDNGFFNQS
>NZ_CP014485.1|WP_037843783.1|6028765_6029878_+|hypothetical-protein
MAHLCGLCLALRGQAGQFARVVTNYDGLVISVLTEAQAGAERAGRRRAGPCALRGMRRASVAEGDGARLAAAVSLILASAKTRDHVTDQDGLLAHRPVAAAARRIAGVWDKEGARAGAGVGFDTALLVGAVERQPEVEALAGPGTPLLAVTEPTETATAAAFAHTAHLAGIPGNAAPLAEAGRLFGRLAHLLDAVEDQEKDAASGAWNPLTATGTPRAEARRLAADALHGIRLALDEAEFTDGRLAHVLLVHELGRSVERAFGEERHRHGAEAHGPAPGNPYAPGAPPHPGGPGDLPPPPPPREPRGLIPGCLVFVGMACTCQMCCGTYEGPWSRRRRDGMCKSCGDCCECCSCCSDGCQCCECCGCCDC
>NZ_CP014485.1|WP_030770087.1|6029894_6030881_-|ABC-transporter-substrate-binding-protein
MSSPLPPGTARRTARRQKGLFALVTVAALTLTACGGQGGQAEAGGAGRPGSEAGAVSLPTEDVVSGVRKDPAAAKLLPAALRDGGEISLAASVGSPPSSTYLDDGKTVAGLDRDVSDAAAKVLGLTVEREVASFEAILPALGSGKYQVGTGNFGVTDDRRATLDFVTYINDGQGFAVREDSTLKKVTDLTQLCGLNIATGAGTTFEVTLEENRPRCAEQGEKPYQVRTYAEQGALWGSLQQGRSDVVMSTINGLRYAVDQQPGLKFLNEYQRLDVGLAFKKGTPLAPAFQAAVDHLIEDGTYARILEKWGVTGSALKESRISPPELKS
>NZ_CP014485.1|WP_030309498.1|6031487_6032402_+|amino-acid-ABC-transporter-permease
MPPTPPAAPAPSPTGEAPAAPVLSKEAEPAPPRVVPVRRTGQWAAAAVVLLLLAMAVNSVVRNEAFQWGVVADYFTTPAVLRGLGLTLWLTALVMVLGFVLGTLLAVARMSANPVLKSVSWGYIWFFRSTPVLVQLLFWFNIGALYPQLGLGIPFGPEFLTVRTVNLLGPLTVALIGLTLHEAAYAAEVVRGGLLSVDRGQTEAAQSLGLGRWRRLRRIVLPQAMRAIVPPAGNMLIGTLKGTSIVSVIAVQDLLYSVQLVYHRTYQVIPLLLVATLWYALVTTVLTVGQHYVERYYGRSERDR
>NZ_CP014485.1|WP_061405134.1|6032398_6034300_+|FAD/NAD(P)-binding-protein
MTPALVVVGAGPRGTGVLERIAANLTEVYGDHPLDIHLVDPHPPGGGRIWRHDQSPLLWMNSHAEDVTLFTDDTVEMAGPVTPGPDLAAWAAAYRESTLPPPAVAAGPELDAEIRGLTPAGFASRRLQSAYLGWVHARVRAALPPQVTVHEHRRAAVRVEGAPDGLQRVWLAGSGTPLTADAVLLTLGHLDTEPDDEQRALTAFAARHGLAHLPPAYTADSDLSALAPGAPVLVRGLGLAFVDLMVLVTEGRGGRYTTSADGRLVYHPSGAEPVLYAGSRRGVPYRSKIGYGWQGDPPPLPRFLTAEVVDALHATAGPGGPDFTRDLWPLIDKELGWAHYHRLFTTRPGATRIAWDDFAEKYAAAAPLSEELRTLVATAVPDPADRLDLAALDRPLAGTVHPDPAALQTALRAHIAADLDRRHDPAHSPDLAVFLGLLSVYGQLLRLGDSGQRWHGFFSYLASGPPGPRLRQLAALSEAGIVHFLGPDTAFTADEESGLFRAASPAVPGHHVEARVLVEARLPDAAAVRSADPLPRGLLGDGAATGPGGLLRVDPADGRLLGLGGLPHPRRFALGPHTDARGAGAFTRPRTNSSSFRQNDATARALLALLRGTGERVPVPVPSPSRGTHVPDQ

Crispr_ID: NZ_CP014485_37

• CRISPR_ID: NZ_CP014485_37
• CRISPR_location: 6360938-6361023
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP014485_37

Consensus_repeat	Method
TGGCCTCAAGCGCCGGCCGGGCTG	CRISPRCasFinder

spacers of NZ_CP014485_37

>37.1|6360962|38|NZ_CP014485|CRISPRCasFinder
TTTTCGGCCGGGCCTCGGGTGACCGGGCCGGTCAAAGA

CRISPR arrays and Neighbor proteins around NZ_CP014485_37

CRISPR arrays

The CRISPR arrays of NZ_CP014485_37

>merge|NZ_CP014485|37|6360938-6361023|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTGTTTTCGGCCGGGCCTCGGGTGACCGGGCCGGTCAAAGATGGCCTCAAGCGCCGGCCGGGCTG

>NZ_CP014485|37|30|6360938-6361023|CRISPRCasFinder
TGGCCTCAAGCGCCGGCCGGGCTG	TTTTCGGCCGGGCCTCGGGTGACCGGGCCGGTCAAAGA
TGGCCTCAAGCGCCGGCCGGGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_018895767.1|6362269_6362668_+|barstar-family-protein	unknown	unknown	gnl|CDD|376530
NZ_CP014485.1|WP_061405206.1|6366386_6367172_+|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl|CDD|143600
NZ_CP014485.1|WP_003947007.1|6359080_6359767_+|ribulose-phosphate-3-epimerase	unknown	unknown	gnl|CDD|235515
NZ_CP014485.1|WP_061405538.1|6361213_6361693_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|211538
NZ_CP014485.1|WP_061405205.1|6362681_6363878_-|AlkZ-family-DNA-glycosylase	unknown	unknown	gnl|CDD|377630
NZ_CP014485.1|WP_003947006.1|6359875_6360928_+|transcriptional-regulator	unknown	unknown	gnl|CDD|367868
NZ_CP014485.1|WP_008406376.1|6365733_6366192_+|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NZ_CP014485.1|WP_079076051.1|6350158_6351436_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP014485.1|WP_030309604.1|6354890_6355835_+|methionyl-tRNA-formyltransferase	unknown	unknown	gnl|CDD|234567
NZ_CP014485.1|WP_008406393.1|6358457_6359012_+|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NZ_CP014485.1|WP_061405202.1|6355959_6357396_+|rRNA-cytosine-C5-methyltransferase	unknown	unknown	gnl|CDD|237857
NZ_CP014485.1|WP_061405203.1|6357552_6358398_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|184875
NZ_CP014485.1|WP_018471482.1|6367226_6368921_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366721
NZ_CP014485.1|WP_003947000.1|6364170_6365637_+|GuaB1-family-IMP-dehydrogenase-related-protein	unknown	unknown	gnl|CDD|181127
NZ_CP014485.1|WP_008406369.1|6368937_6369633_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_008406411.1|6349338_6350094_-|toll/interleukin-1-receptor-domain-containing-protein	unknown	unknown	gnl|CDD|379328
NZ_CP014485.1|WP_061405207.1|6369730_6370639_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NZ_CP014485.1|WP_008406404.1|6354008_6354518_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405201.1|6351645_6353781_+|primosomal-protein-N'	unknown	unknown	gnl|CDD|237844
NZ_CP014485.1|WP_061405204.1|6361799_6362225_+|ribonuclease-N	unknown	unknown	gnl|CDD|238340

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_018895767.1|6362269_6362668_+|barstar-family-protein	gnl|CDD|376530	pfam01337, Barstar, Barstar (barnase inhibitor).	1.65582e-22
NZ_CP014485.1|WP_061405206.1|6366386_6367172_+|carbon-nitrogen-hydrolase-family-protein	gnl|CDD|143600	cd07576, R-amidase_like, Pseudomonas sp. MCI3434 R-amidase and related proteins (putative class 13 nitrilases). Pseudomonas sp. MCI3434 R-amidase hydrolyzes (R,S)-piperazine-2-tert-butylcarboxamide to form (R)-piperazine-2-carboxylic acid. It does so with strict R-stereoselectively. Its preferred substrates are carboxamide compounds which have the amino or imino group connected to their beta- or gamma-carbon. This subgroup belongs to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), class 13 represents proteins that at the time were difficult to place in a distinct similarity group. It has been suggested that this subgroup represents a new class. Members of the nitrilase superfamily generally form homomeric complexes, the basic building block of which is a homodimer. Native R-amidase however appears to be a monomer.	3.75284e-109
NZ_CP014485.1|WP_003947007.1|6359080_6359767_+|ribulose-phosphate-3-epimerase	gnl|CDD|235515	PRK05581, PRK05581, ribulose-phosphate 3-epimerase; Validated.	7.4073e-136
NZ_CP014485.1|WP_061405538.1|6361213_6361693_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl|CDD|211538	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c., deazaflavin-dependent oxidoreductase, nitroreductase family. This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity].	5.86778e-09
NZ_CP014485.1|WP_061405205.1|6362681_6363878_-|AlkZ-family-DNA-glycosylase	gnl|CDD|377630	pfam06224, HTH_42, Winged helix DNA-binding domain. This family contains two copies of a winged helix domain.	1.71603e-39
NZ_CP014485.1|WP_003947006.1|6359875_6360928_+|transcriptional-regulator	gnl|CDD|367868	pfam04198, Sugar-bind, Putative sugar-binding domain. This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC. These proteins have an amino-terminal helix-turn-helix pfam00325 that binds to DNA. This domain is probably the ligand regulator binding region. SorC is regulated by sorbose and other members of this family are likely to be regulated by other sugar substrates.	2.83531e-73
NZ_CP014485.1|WP_008406376.1|6365733_6366192_+|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.02655e-29
NZ_CP014485.1|WP_079076051.1|6350158_6351436_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.74401e-09
NZ_CP014485.1|WP_030309604.1|6354890_6355835_+|methionyl-tRNA-formyltransferase	gnl|CDD|234567	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed.	7.89982e-167
NZ_CP014485.1|WP_008406393.1|6358457_6359012_+|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	7.70643e-43
NZ_CP014485.1|WP_061405202.1|6355959_6357396_+|rRNA-cytosine-C5-methyltransferase	gnl|CDD|237857	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB.	7.59939e-95
NZ_CP014485.1|WP_061405204.1|6361799_6362225_+|ribonuclease-N	gnl|CDD|238340	cd00607, RNase_Sa, RNase_Sa. Ribonucleases first isolated from Streptomyces aureofaciens. In general, ribonucleases cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. RNAse Sa is a guanylate specific endoribonuclease which belongs to the superfamily of microbial ribonucleases. Typical of this sub-family, the enzyme hydrolyses the phosphodiester bonds of RNA at the 3' oxygen end of guanosine residues to yield oligonucleotides with the guanosine-2',3'-cyclophosphate at the 3' end and the hydroxyl group at the 5' end. The terminal guanosine-2,3'-cyclophosphate is hydrolysed by guanyl RNAses to give guanosine-3'-phosphate.	3.36275e-42
NZ_CP014485.1|WP_018471482.1|6367226_6368921_+|FAD-dependent-oxidoreductase	gnl|CDD|366721	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.	4.49443e-46
NZ_CP014485.1|WP_003947000.1|6364170_6365637_+|GuaB1-family-IMP-dehydrogenase-related-protein	gnl|CDD|181127	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein.	0
NZ_CP014485.1|WP_008406411.1|6349338_6350094_-|toll/interleukin-1-receptor-domain-containing-protein	gnl|CDD|379328	pfam13676, TIR_2, TIR domain. This is a family of bacterial Toll-like receptors.	1.19599e-07
NZ_CP014485.1|WP_061405207.1|6369730_6370639_-|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.52105e-58
NZ_CP014485.1|WP_061405201.1|6351645_6353781_+|primosomal-protein-N'	gnl|CDD|237844	PRK14873, PRK14873, primosomal protein N'.	0
NZ_CP014485.1|WP_061405203.1|6357552_6358398_+|alpha/beta-fold-hydrolase	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	8.33915e-23

Protein sequences

>NZ_CP014485.1|WP_003947006.1|6359875_6360928_+|transcriptional-regulator
MNSSEEIAVSGMSAGRPALRMGPAELVQAAAMARRFYLEGKSKIQIAEEFGVSRFKVARVLETALERDLVRIEIRVPAELDAERSDALRARFGLRHAVVVESPAEEEESPDPESLGEVAADLLGELVTEGDVLGLAWGRSTIHMAAALDKLPPCTVVQLTGVYDAGTAERGSVEAVRRAAQVAGGEAHPIYAPMLLPDPATAAALRNQTGIARAFEHFDKVTVAAVSIGSWEPGISTVHDMLSEEERAHYASLGVAAEMSAHLFDAEGRRVGRDLGERCITVEADRLRRIPEVVAIAGGGRKAPAIDAVLRSGLVTSLVTDTAAADQLLAAAPPPRPALDRADPDEPGDA
>NZ_CP014485.1|WP_003947007.1|6359080_6359767_+|ribulose-phosphate-3-epimerase
MAAQINPSILSADFARLADEARAVEGADWLHVDVMDNHFVPNLTLGVPVVESLARATETPLDCHLMIEDPDRWAPQYVEAGAGSVTFHVEAAAAPVRLAREIRAKGARAAMALKPATAIEPYEELLPELDMVLIMTVEPGFGGQSFLDLTLPKIRRTRELIGRHGLDLWLQVDGGVSAATIERCAEAGADVFVAGSAVYGAEDPAEAVRSLRDSARKATASAPWACGH
>NZ_CP014485.1|WP_008406393.1|6358457_6359012_+|DinB-family-protein
MNATPRKRADLFLPVEDDPRQNGPTLGDEVTTLMEYLRCQRLTLEVKCAGLDAEQLARRSVEPSTMSLLGLVRHMADVERVWFRARMAGLDAPPYFRLPEDPDGDWDGALPDPALVEEAWRLLRAEQEFGDAFVARAPSLDLTGEAHGEPVSLREVLVHLVEEYARHNGHADFLRERIDGRVGE
>NZ_CP014485.1|WP_061405203.1|6357552_6358398_+|alpha/beta-fold-hydrolase
MSEWELSRTYGSSAGEVRWERLGDPAAPPVVLCHGTPFSSYVWRRIARELARDHQVYVWDMPGYGVSAQFEGQDVSLGAQGRVFAELLAHWDLAAPAVVAHDFGGAVALRAHLLHGAAYRRLALVDPVALAPWGSAFFRLVGEHHGVFEQLPPHLHRALVREYISSASSPGLDPAVLDRLVQPWEGVEGQPAFYRQIAQAGQRYTDEIQGRYGSIELPVAVFWGEDDAWIPVAKAHELAAAVPGAELVLIPGAGHLVQEDAPGRLGTGLARFLGAAEQGAR
>NZ_CP014485.1|WP_061405202.1|6355959_6357396_+|rRNA-cytosine-C5-methyltransferase
MTDQPSRRPRKTGKPYRRPKKDPVRILAFEALRAVDERDAYANLVLPALLRKAREDHPDTFEARDAALATELVYGTLRRQGTYDAIIAACVDRPLREVDPPVLDVLSLGAHQLLGTRIPSHAAVSATVELARVVLGDGRAKFVNAVLRRITADDLDGWLERVAPPYDEDPEDHLAVVHSHPRWVVSALWDSLGGPRAGIEDLLEADNERPEVTLVARPGRTTSDTLLDGLGPDRALPGRWSPYAVRLTEGGEPGAIDAVREGDAGVQDEGSQLVALALAAAPLEGSDSRWLDACAGPGGKAALLAGLAAQRGATLLASEKQPHRAGLVAKALDGNPGPYQVIAADGTRPPWRPGSFDRVLVDVPCTGLGALRRRPEARWRRRPEDLDGFAPLQRALLRTALESVRGGGVVAYATCSPHLAETRAVVDDVLKREGGAELLDARPLMPGVPALGEGPDVQLWPHLHGTDAMYLALLRRTA
>NZ_CP014485.1|WP_030309604.1|6354890_6355835_+|methionyl-tRNA-formyltransferase
MRLVFAGTPEVAVPALDALIASERHEVVAVVTRPDAPAGRGRRLVASPVAERAEEAGIEVLKPNRPRDEEFLARLREIGPDCCPVVAYGALLPKVALDIPARGWVNLHFSLLPAWRGAAPVQHAILAGDQITGASTFLIEEGLDSGPVFGTVTEEVRPTDTSGDLLTRLAFAGSGLLAATMDGIEDGTLQAVPQPADGVSLAPKLTVEDAQVDWAAPALRVDRVVRGCTPAPGAWTVFRGERLKLVAARPLPGEEGLAPGDLAVGKNHVHVGTGSHAVELLWVQPQGKKPMRAADWARGVRIAPGERLGAADVR
>NZ_CP014485.1|WP_008406404.1|6354008_6354518_-|hypothetical-protein
MADHATHDAQARASLHLLVRDIERVRRQVDALRTLTAQLGNVYRPRRTGPATGFVVYGRAPAPTVRLAQELRDSVETLVTAAVDFDRSLGFSWDAVGSALGVTKQAVHRRYGARRATTQAAAEAERAGETSTSTRPVPLNTGLPTVPAARSMPTQPTPRPSALPGPRHG
>NZ_CP014485.1|WP_061405201.1|6351645_6353781_+|primosomal-protein-N'
MSSEDEGAGERSGREPEQLALVREMARQAKAPKAKPRTWRGADVAEHLPVARVVVDKGVLHLDRYFDYAVPKELDAEAQPGVRVRVRFSAGAGRVHAGRREGGGLISGFIVDRLAESDYDGPLAALAQVVSPEPVLTQELLGLARAVADRYAGSLADVLQLAVPPRNAKAEAAASPDPLPPPSVPEAGSWERYGPAGPGLLAELARGGAPRAVWTALPGPQWAEELARAVAATLASGRGALVVLPDGRHAARVDAALTALLGKGHHTLLTADAGPQKRYRQWLAVHRGSVRAVVGTRAAMFAPVRDLGLVALWDDGNENHSEQHAPQPHAREVLMLRAAHENSAVLLGSVSCTVEAAQLVDSGWAVPVAADRAVTRAAAPRVRTIADHDLARDAAARTARLPSLAWQALRDGLREGPVLVQVPRRGYVPRLACERCREPARCRQCAGPLQAAESSLLHCAWCGRPEADWHCEECGGFRLRAQVTGARRTAEELGRAFPSVPVRTSGREQVLDTVDAAPALVVSTPGAEPVAEGGYAAAVLLDGWALLNRPDLRAGETALWRWMSASALVRGQSAGGTVVIVAEPTLAPVQALVRWDPVGYALREYADRSELGFPPVSRMAAVAGPQAAVAEFLGAVELPPDAEILGPVPLHESAERGRGRAGEGPQVRALVRVPPGSGMALAHALKTAQAARMARGGRVPVRVRVDPLDIG
>NZ_CP014485.1|WP_079076051.1|6350158_6351436_-|helix-turn-helix-transcriptional-regulator
MHVPPKRFGAELRRARHERGMTLTRLASAVHYSKSQLSKIENGHQRPTAHLARRCEVELDCPGRLIALLPDPATPTSPAAAGPPSRRLVLTAGAATVLLAGGAPGGAAASAPGEQAGDGSLVDSARALLTHFRRMAQSCPPPTVLVPLAEQTRALVALAADSGSGARNGLLLVAARFAEFTGWMAQESGHDEAARRWTDHAARLAFDGGDHQLGHYGLVRRALMAYYRGHAAETVALSAAAGDHRLAPRIRGLAAQQEAEGHALAGDHGASLRTLDRARDLLAAAEREEDPAPVGTSHLTDPVTMFTGWCLYDLGRPAAAAEHLDAACAALPPQAHRNLARYGVRRALAHASAGEIDHACALARTALTSASAVASYTIGLDLRRLAGVLGRHREHSGVRALAPDLTAALTLSAAARTAPPLPKPA
>NZ_CP014485.1|WP_008406411.1|6349338_6350094_-|toll/interleukin-1-receptor-domain-containing-protein
MPHVFINYRTGDGEQASAHLDDALRQRFGDNASFRDGRSISLGRTFQEELRENVRACEVLLVLAGPGWSARPELWREGDWVREEILEALRNDVLIVPVLLGRGTARPARADLPPELASVADRQCLTYEAHRAEYDVPAILQALTKVVPAFADAEEERAQATETTTNRMREVEGVSAVQTGSAGDISTTVNGSTGAGSTTTHFHAATGSVHTGSGNQHLPQFSGDGPVNYTADNHGTVHNSFGNRTADQEKK
>NZ_CP014485.1|WP_061405538.1|6361213_6361693_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MEVPEEFEGDQPEELGPFAVRLNSLVGRLARLGISLLGSAELTVVGRRSGTPQRIPVNPHTHEGAEYLVSARGHSQWVRNMRAAGGGTLRLGRRTRAFHAEELPDNALKAEILRTYLARWGWEVNDYFQGVTARSPEADLLSACPDHPVFRITTTPQKK
>NZ_CP014485.1|WP_061405204.1|6361799_6362225_+|ribonuclease-N
MFSRSRRPRALLRVSLTALLCTLMALLTGCSAEQGGTSSGGAPAPAWAEGMATVREDRLPAEARDTLRLIDRGGPFPYAKDGSVFGNYEKLLPERKRGHYREYTVKTPGARDRGARRLVTGREDEIYWTEDHYASFRAVLR
>NZ_CP014485.1|WP_018895767.1|6362269_6362668_+|barstar-family-protein
MSDDDSRTGPPARPADPVARAVAAAREAGQPCAVLDLAGVRDKAGFLEACAGQLGLPGWFGRNWDALADLLGDPDSLPLADGGVLVVRGWRELAAASPGDWETARTLLGDSAADARESGRGVTALLALEGEG
>NZ_CP014485.1|WP_061405205.1|6362681_6363878_-|AlkZ-family-DNA-glycosylase
MTDGQRRARLGVRHALAPSARADDPAGAARAVVALHSTDPSSVHVAAWARTRDEQADAASVERALYEDRALVRLLAMRRTVFVAPVETAAVLQAACSREVAARERRKLEGFVAASVPAPGGSAAGWLAGAEEAALASLAARGEATAADLAADDPRLAAQVRIGGASRHARGQSVAARLLLLLAAEGKAVRGRPRGSWTSHQYRWSPLSAWLPDGLAPWETEAARAELARLWLRAYGPGTAEDLRWWTGWTKTQTTRALKEVAPAEVELDDGSTGLVLADDLDPVPDPGPWAALLPALDPTPMGWHSRAWYLGPHQDRLYDRAGNIGPSVWWCGRIVGGWAQDRDGALVCRYLEDVGADARAAVDAEAERLAPRLGDVRLTARTRGRTWLEEELAAGSG
>NZ_CP014485.1|WP_003947000.1|6364170_6365637_+|GuaB1-family-IMP-dehydrogenase-related-protein
MRFLEPGTGRHTSIPPVAYDLTYDDVFMVPRRSAVGSRQAVDLSSPDGTGTTIPLVVANMTAIAGRRMAETTARRGGLTVIPQDIPIEVVTEVTQWVKQRHLVLDTPIVLAPTQTVGDALSLLPKRAHNAGVVVDENHRPVGVVTDEDLTDVDRFTQLADVMSRDLLLLDADIAPGDAFDTLDGANRRYAPAVGADGRLVGILTRTGALRATLYQPNVDAQGRLRIAAAVGINGDVAGKARQLLDAGVDTLVVDTAHGHQESMVRAVRAVRALDPQVPIVAGNIVAAEGVRDLVEAGADIIKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAEARSLGKHVWADGGVRHPRDVAMAVAAGASNVMVGSWFAGTYESPGDLQQSADGRLYKESYGMASARAVRNRTSEESAYDRARKALFEEGISTSRMFLDPQRPGVEDLIDSIIAGVRSSCTYAGAASLAEFAERAVVGVQSAAGYAEGKPLHASWS
>NZ_CP014485.1|WP_008406376.1|6365733_6366192_+|Lrp/AsnC-family-transcriptional-regulator
MRLNDLDERIVHALADDARRSYADIGALVGLSAPAVKRRVDRLRAEGAITGFTVRVDPAALGWRTEGYIEIYCRPHTSPQDIRRGLERYPEVAAASTVTGEADALAQIFAADMRHFEDVLERIAGEPYVERTKSVLVLSPLLRRTTVTSTAG
>NZ_CP014485.1|WP_061405206.1|6366386_6367172_+|carbon-nitrogen-hydrolase-family-protein
MPPSLRTALLQSAPAPADALDRLDEAARRAAADGARLLVTSELYLTGYTPEAGFDALAEPADGPSARAVSALAARHGLAVVHGYAERGADGRLHNSAALTGPDGTPLAHYRKTHLYGDHEHRWFTPGDRSVVQARLDGLTLGLLVCYDVEFPETVRAHALAGTDLLCVPTALAEPFTVVPDTLVPARAVESQLYVAYANRTGTEGPYTFAGRSCLAAPDGTVPVRGGRDEALLLADADPARLAASRADSPYLRDRRPELYG
>NZ_CP014485.1|WP_018471482.1|6367226_6368921_+|FAD-dependent-oxidoreductase
MTSTVPPAGRPAAGLPPITMVGPDFPFPYDDYLGHAAGLGQIPATAHGTEVAVIGGGLSGIVTAYELMKMGLKPVVYEADQIGGRLRTVGFDGCDPGLRAEMGAMRFPPSSTSLQHYIDLVGLQTRPFPNPLSPATPSTVVDLKGESHYARTLDDLPQVYRDVADAWQRCLDEGAEFGDMNEALRTRDIPRIREIWARLVERLDDQTFYGFLAGSEAFRSFKHREIFGQVGFGTGGWDTDFPNSILEILRVVYTEADDHHRGIVGGSQQLPLRLWERAPGKLVHWPQGTSLASLHEGGAPRGAVTRLHRTAGGGITVTDASGAIRTYPAAVFTGQSWLLLSKIACDETLFPMDHWTAMERTHYMESSKLFVPVDRPFWLDKDPATGRDRMSMTLTDRMTRGTYLLDDGPDKPAVICLSYTWCDDSLKWLPLSPAERMEVMLASLGEIYPDVDIRRHIIGSPVTVSWENEPWFMGAFKANLPGHYRYQRRLFTHFMQDGLPADRRGIFLAGDDISWTAGWAEGAVQTALNAVWGVMHHFGGTTDPTNPGPGDRFDELAPVELPED
>NZ_CP014485.1|WP_008406369.1|6368937_6369633_-|hypothetical-protein
MKRTSGTARDAGSLDATVARMREVGAGCPPPDGVGVFNSVYLTVTEELARRIGAGAFPDVRAASTLTTLFAGRYLDAVSAEAAGERVPACWRPLFAQRRHPGVRPLQFALAGIQAHVGHDLPLAVVDSCRALGCRPAALEDEFDTVGEVLRSLEERVREELMPGPDLLELADPLTHLAGAWSLDRARDGAWAAARTLWVVRGVEELGEEFVRRLDTSVGLVARMLLTPLRR
>NZ_CP014485.1|WP_061405207.1|6369730_6370639_-|LysR-family-transcriptional-regulator
MQVLRAVVETGSVAAAAGRLGYTPSAVSQQVAALEAQAGTPLLERVGRGVRPTEAGTLLAGHAELIGGQVALAEAALADLRAGRTGRLTVRYFATAGPGLLAPALARFRDQHPGVGVELRLSEPDDPLAEVAEGRADLGLVVRPDAPPPPGVDLVRLLDDPYRVALPPDHPLAGREVVDLADLAEEPWIGSEPPGPCLHAVLQGCAAAGFTPEVAVECQDYTTAQGFVAAGLGVALLPRLGLAVPHPGVTVRPVRGPEPARTIRAALRSGAPRTPALTGLLTALREAAGPLGGSFSAHPYGS

Crispr_ID: NZ_CP014485_38

• CRISPR_ID: NZ_CP014485_38
• CRISPR_location: 6635413-6635679
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP014485_38

Consensus_repeat	Method
CACCCCCGCTCGCGCGGGGACGAC	CRISPRCasFinder
CCCCCGCTCGCGCGGGGACGAC	CRT
GTCGTCCCCGCGCGAGCGGGGGTGGTCC	PILER-CR

spacers of NZ_CP014485_38

>38.1|6635437|37|NZ_CP014485|CRISPRCasFinder
AACGTGTTGCCGTTGATCGTCACGTCCTCGTAGGGAG
>38.2|6635498|37|NZ_CP014485|CRISPRCasFinder
GCCGAGTCGCTCGCCGACGGCGCCGAGAAGGTCGGAC
>38.3|6635559|36|NZ_CP014485|CRISPRCasFinder
ATCAGCAGGGCTCGGATGAACACCTGGATGCGGGGA
>38.4|6635619|37|NZ_CP014485|CRISPRCasFinder
ATGGTGCGGGGCGCCTCGCGGGAGCTGGACCGGGGAC
>38.5|6635437|39|NZ_CP014485|CRT
AACGTGTTGCCGTTGATCGTCACGTCCTCGTAGGGAGCA
>38.6|6635498|39|NZ_CP014485|CRT
GCCGAGTCGCTCGCCGACGGCGCCGAGAAGGTCGGACCA
>38.7|6635559|38|NZ_CP014485|CRT
ATCAGCAGGGCTCGGATGAACACCTGGATGCGGGGACC
>38.8|6635619|39|NZ_CP014485|CRT
ATGGTGCGGGGCGCCTCGCGGGAGCTGGACCGGGGACCA
>38.9|6635498|33|NZ_CP014485|PILER-CR
GCCGAGTCGCTCGCCGACGGCGCCGAGAAGGTC
>38.10|6635559|39|NZ_CP014485|PILER-CR
ATCAGCAGGGCTCGGATGAACACCTGGATGCGGGGACCA
>38.11|6635626|33|NZ_CP014485|PILER-CR
ATGGTGCGGGGCGCCTCGCGGGAGCTGGACCGG

CRISPR arrays and Neighbor proteins around NZ_CP014485_38

CRISPR arrays

The CRISPR arrays of NZ_CP014485_38

>merge|NZ_CP014485|38|6635413-6635679|CRISPRCasFinder,CRT,PILER-CR
CCCCCGCGCTCGTGCGGGGACGACAACGTGTTGCCGTTGATCGTCACGTCCTCGTAGGGAGCACCCCCGCTCGCGCGGGGACGACGCCGAGTCGCTCGCCGACGGCGCCGAGAAGGTCGGACCACCCCCGCTCGCGCGGGGACGACATCAGCAGGGCTCGGATGAACACCTGGATGCGGGGACCACCCCGCTCGCGCGGGGACGACATGGTGCGGGGCGCCTCGCGGGAGCTGGACCGGGGACCACCCCCGCTCGCGCGGGGACGAC

>NZ_CP014485|38|31|6635413-6635679|CRISPRCasFinder
CCCCCGCGCTCGTGCGGGGACGAC	AACGTGTTGCCGTTGATCGTCACGTCCTCGTAGGGAG
CACCCCCGCTCGCGCGGGGACGAC	GCCGAGTCGCTCGCCGACGGCGCCGAGAAGGTCGGAC
CACCCCCGCTCGCGCGGGGACGAC	ATCAGCAGGGCTCGGATGAACACCTGGATGCGGGGA
CCACCCCGCTCGCGCGGGGACGAC	ATGGTGCGGGGCGCCTCGCGGGAGCTGGACCGGGGAC
CACCCCCGCTCGCGCGGGGACGAC

>NZ_CP014485|38|5|6635415-6635679|CRT
CCCGCGCTCGTGCGGGGACGAC	AACGTGTTGCCGTTGATCGTCACGTCCTCGTAGGGAGCA
CCCCCGCTCGCGCGGGGACGAC	GCCGAGTCGCTCGCCGACGGCGCCGAGAAGGTCGGACCA
CCCCCGCTCGCGCGGGGACGAC	ATCAGCAGGGCTCGGATGAACACCTGGATGCGGGGACC
ACCCCGCTCGCGCGGGGACGAC	ATGGTGCGGGGCGCCTCGCGGGAGCTGGACCGGGGACCA
CCCCCGCTCGCGCGGGGACGAC

>NZ_CP014485|38|11|6635470-6635679|PILER-CR
GGAGCACCCCCGCTCGCGCGGGGACGAC	GCCGAGTCGCTCGCCGACGGCGCCGAGAAGGTC
GGACCACCCCCGCTCGCGCGGGGACGAC	ATCAGCAGGGCTCGGATGAACACCTGGATGCGGGGACCA
CCCCGCTCGCGCGGGGACGACATGGTGC	GGGGCGCCTCGCGGGAGCTGGACCGGGGACCAC
CCCCGCTCGCGCGGGGACGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014485.1|WP_061405325.1|6642005_6643997_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_079076087.1|6638064_6638262_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_107251623.1|6638680_6638953_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP014485.1|WP_061405324.1|6640971_6641985_+|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl|CDD|176257
NZ_CP014485.1|WP_061405319.1|6636817_6637987_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP014485.1|WP_079076059.1|6632806_6633622_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP014485.1|WP_158516865.1|6624944_6627236_+|hypothetical-protein	unknown	unknown	gnl|CDD|227605
NZ_CP014485.1|WP_061405317.1|6635719_6635956_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405316.1|6634760_6635084_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_059213656.1|6634273_6634558_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405314.1|6633621_6633966_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405315.1|6633979_6634240_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_158516866.1|6635070_6635244_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_123985165.1|6640124_6640328_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP014485.1|WP_079076086.1|6630662_6630965_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_123985164.1|6639031_6639961_-|hypothetical-protein	unknown	unknown	gnl|CDD|197715
NZ_CP014485.1|WP_123985163.1|6634554_6634764_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405323.1|6640364_6640604_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405309.1|6627245_6630623_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP014485.1|WP_061405318.1|6636148_6636685_-|flavoprotein	unknown	unknown	gnl|CDD|273116

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014485.1|WP_158516865.1|6624944_6627236_+|hypothetical-protein	gnl|CDD|227605	COG5280, COG5280, Phage-related minor tail protein [Function unknown].	1.70756e-11
NZ_CP014485.1|WP_061405324.1|6640971_6641985_+|alcohol-dehydrogenase-AdhP	gnl|CDD|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.01325e-157
NZ_CP014485.1|WP_061405319.1|6636817_6637987_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.51243e-07
NZ_CP014485.1|WP_123985165.1|6640124_6640328_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.000237026
NZ_CP014485.1|WP_123985164.1|6639031_6639961_-|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	3.51121e-06
NZ_CP014485.1|WP_107251623.1|6638680_6638953_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.57576e-16
NZ_CP014485.1|WP_079076059.1|6632806_6633622_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	5.8427e-21
NZ_CP014485.1|WP_061405318.1|6636148_6636685_-|flavoprotein	gnl|CDD|273116	TIGR00521, coaBC_dfp, phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase. This model represents a bifunctional enzyme that catalyzes the second and third steps (cysteine ligation, EC 6.3.2.5, and decarboxylation, EC 4.1.1.36) in the biosynthesis of coenzyme A (CoA) from pantothenate in bacteria. In early descriptions of this flavoprotein, a ts mutation in one region of the protein appeared to cause a defect in DNA metaobolism rather than an increased need for the pantothenate precursor beta-alanine. This protein was then called dfp, for DNA/pantothenate metabolism flavoprotein. The authors responsible for detecting phosphopantothenate--cysteine ligase activity suggest renaming this bifunctional protein coaBC for its role in CoA biosynthesis. This enzyme contains the FMN cofactor, but no FAD or pyruvoyl group. The amino-terminal region contains the phosphopantothenoylcysteine decarboxylase activity. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A].	2.55014e-08

Protein sequences

>NZ_CP014485.1|WP_158516866.1|6635070_6635244_+|hypothetical-protein
MPDPEPRPAERRIDPAAGDTAALAALGLADPVPIPSADPFREPVYPDGPWPGPDDED
>NZ_CP014485.1|WP_061405316.1|6634760_6635084_+|hypothetical-protein
MSFAQLLNTSVSALVALSAAVFVVTYHRLAPWRSTPMGWHLMLLAATLGLLGLYTVVITIVGLDGTPATVLRIVRAGLLLLVAGLLAQRTLMVTRAQRPEGDPHARP
>NZ_CP014485.1|WP_123985163.1|6634554_6634764_+|hypothetical-protein
MKWPWRRRHGGRSPGQAAADRALHRARADRQEAADRQPAVQETAETLRRYREENHFAQLFRASIEGRRA
>NZ_CP014485.1|WP_059213656.1|6634273_6634558_+|hypothetical-protein
MGELFGLKIADLGAVTLLALVVLMVLTGRLVPRRTYDDLKEERDTWRQAHVVSEEARAMERAQTRELLELGRTGAHALAGLRAAAADSEEVGTG
>NZ_CP014485.1|WP_061405315.1|6633979_6634240_+|hypothetical-protein
MADHISLPDAQTVVKTGAAYARDLAERTAATFLQAFVGGVVLTQPFDLAMWQAAAVGGVAAAGALLKGLVARWRDVTNSASLAKGV
>NZ_CP014485.1|WP_061405314.1|6633621_6633966_+|hypothetical-protein
MPILNLTPHPIRLYANEREDGTDDLDPHLREVYAPEPTPARLATFEVSSGMWPVLVEFGHAQNLPPKRDGYQYIVSLVVALALATRRGDLLVPYREVRNASGTVIGCRSFAQPV
>NZ_CP014485.1|WP_079076059.1|6632806_6633622_+|N-acetylmuramoyl-L-alanine-amidase
MAPPMTPATFLAALKAEGVTVVEVGSWRTHNRNSKGAWGPLNGVMIHHTVTSGSARTVEICRNGYSGLPGPLCHGVITKDGRVHLVGYGRANHAGAGDDDVLSAVIAERALPKPDEANTDGNARFYGFECENLGDGKDPWPAAQLDAIERVSAAICRMHGWDAASVIGHLEWQPGKVDPRGFTMSSMRDRIERRLSAPPGKTPTPTTPDKETPMSYRDVWEQDAAPAPDSSPTKKTNPTWKPISFLREIYDLARETRDLVRDIRDQQKRGS
>NZ_CP014485.1|WP_079076086.1|6630662_6630965_+|hypothetical-protein
MRITAERLRAGLLTGTVNITPTENVPASGALGAYLRGTAAVTFPAGTFTETPRIFLTGRSSVPGVLIECNYTDQSESGFTITIARQTSTLTVVDWLAVAA
>NZ_CP014485.1|WP_061405309.1|6627245_6630623_+|hypothetical-protein
MAWPDRPQKLPLRTELAFGADPAGDPATWTWTDVSEHVEDQSITINRGRGEEGGETRPASTGLELVNNGGDYTPGHAGGAHYPHVRLGVPARLSVQAGGPHLRLPASGAHAVTGTTSGLTVTDLDIRAEVALDRVAAQFRDVTPGGRRPWQTIAQEITGRSRTDGTLMWHLAADMQGGLLLMWTTASEARQDRSSTDVLPYGSGQRFAARATLDVNNGDGGHTVTFYHAPTMDGPWEILGQPIVTSGTTTILQTDATPLRLGRVTTENRLGAVGRLYRAELRNGINGTILASPDLRTVAPGTTSWTDSTGKAWTLAENAEITDWVPHVTGTVDEWAPHWPWGDLSTPGYDGEARTDVTVSGILRRLGTGQPPLQSALRRRLPAGNPFAYWPLEDEPGATSGASGLDSGKPLNVSGLRFGQSTSLLSSDALPTVTAGARIRANLRAGAQGEWAVTMLYNLAQLPQNDSVFFEVQADRGVWTSYRITLRSNSVVCDAIDDSGSSSSTTRLFNVLTSTFYGGWRRFTLQATQTGNTTEVRGIWRFLDGDGGGSGGGTFTGSAGVLSRIDTTFGAELEGMAIGHLSVMRRADVWVYAAAEDGFAGETALARMRRLAEEERMPLSVIGVEASSPAMGPQRIATLLDLVQECVDADGGILTELRGQPGLQYRSRESLLNQRPALVLDAQANEIAAPFSPVLDDQRTRNRITVSREGGSSATVEDAESIAESGIYDASAQLNVAYDTQLEALAGWRLHLGTVRGMRYPQVGADLAIAPRLIDGWLSVDSGTRMDVTGLPPQHPQGTVPLMVEGTTETITPTRWTVRATCSPASPWTAGVVGDDQLGRVDTDGTVLAGPVASADGAILTRVTAGPTWTRAASELPYVLNADGEEVTVIAVADVFDTFQRTVTGGWGTASGGLPWLLGGGAAAERSVSAGRGVVTVSSATISAVRIQALAGPLGDAEVRVRMSVPQVSTGAALIPGVLLRYADGSNYYRARLHFNAGGTLSTSITRTVTQVGSTVTVSGGYTAGAEFEVRARVDGHRLRMRVWPVGGTEPTIWHQDQTITTDPIEHGLVGVTAGGFTGNTNVDPQIRFDLFEAVGVQRMTVTRPDPQDHAAGGDVRLAQPAIVI
>NZ_CP014485.1|WP_158516865.1|6624944_6627236_+|hypothetical-protein
MQITPSFQGFGSNIMSEVGRELSSGAGRAGEQAGEAAGREFGSSFEERASAAAERMGPIGTAAGVGIAGALGVGLAAAMDASSATAKLTAQLGLTEAEAARVGAISGEVFSAGFGESMGEVSEAVGAVTSSVADLGATSDAELQQLTTTALGLAETFQWDVGEAATAAGNLVKNGLAKDATDAFDVMSQAAKTLPASMRADIPAVVSEYGIHFARIGLDAKTAFGMMSQYVEAGGRDIDQAADVLHEFGRITSEETDRAAEGFKALGLDSSQMLSDIAKGGEPAEAALTATLDALRGVKDPAEQSALAVELFGDMAGEGVDALWAMDPATAAAASGMDKTAGSGKELTDALAADPARVFEGAMRDLTMSLAQELAPALAGVAGWVSDNEGAFKGIVFAVGGIALAVAGATAALRLYQGAIVAVRVATAIWTGIQWLLNAAFWANPMTWVVLGIIALIAIIVLAIVYWNEIVAAVRAAWQWITEATGVAVEWLKVKLGEAWEWIKTTASAAWEAVKATIGGAWQWIKDQTGAAVDWVATKAAAAWEGIKGAAKAAWDGVVLILKLAWATIVQIAAGAVLGLITAISGAWSTIKRATSTAWATVKRSITDAVGRAYDSVKNAGSRFLSVGRDIVNGIVTGVRNAAGRLFGSLRDMASNALSAAKNALGIGSPSRLFADQIGQWIPAGVEVGIDAGQGELDQRVERLVQTPDVPVVRASVATGAAASPAPVVIRADGGRASRVLLELLQQSIRTDLGGDVTRLGTR
>NZ_CP014485.1|WP_061405317.1|6635719_6635956_-|hypothetical-protein
MDIPDSLIDLQRAADAEWARLAELTDNDERERQRRVWFEAGARAQAAITEWAVAENKNRYKVEKAVREAVRHPESGSD
>NZ_CP014485.1|WP_061405318.1|6636148_6636685_-|flavoprotein
MTTLYLFGSAAPPVLGVGTVIEDAQQRGFDVCLGLTPTAARWLEPQTAELERLTGHPVRSEYKAPGTADAWPKADVVLFAPATFNSINAWALGITSSFVVGVCAEGIGKGIPLVTMPCVNAAYAQHRALDRSVAELRDMGVSVLYGEGGFQPNPPGEGREFPWRVAFDEVERAVGAGR
>NZ_CP014485.1|WP_061405319.1|6636817_6637987_+|helix-turn-helix-domain-containing-protein
MPTPDDDSTGGRIRRERRRARLSQRQLADRIPFSYSLLNQVECGARAASTELVAAVAAALRIDVSLLTGSAVTDQLPGQRADIVRPIREALDLYDLAPDVERPTRPVAAMVEAADRVCQQVRATHLRTAASALPDLIADLTHVALTSPSTEGWRALASTYRSAHDVALKLEHRDLAALALERMGWAAERASDPCLAAIRQYKRALSWQDSELGLRLVQAGHDTLDGQSSREALAVAGQLHLGASAVAARARDRAGVARHIEAARELAARTGPAQSIHWLGFGALNVRLHAMGAAITMRQYDDALQQARALRIPPSAMTSRRARFLVDRAMAEMETGLGDTSLRHLVEARAVAPEQTRYLPRTRETVRGLLHTTRRPSERLTRMAAWVGV
>NZ_CP014485.1|WP_079076087.1|6638064_6638262_+|hypothetical-protein
MATTVQELPQPTALGERQLRGTECVWCAGRLDTATAVDLGVRPDPQCPWASWFPRACPACAAGRS
>NZ_CP014485.1|WP_107251623.1|6638680_6638953_-|helix-turn-helix-transcriptional-regulator
MTAAYAAQSVCRVPPQDHPAWLHAERRALGDRIRERRMRQNLTQEKLAEAAGVSRDTVQRIERGTNDPRYSDLARIACALDTPLAKLVGG
>NZ_CP014485.1|WP_123985164.1|6639031_6639961_-|hypothetical-protein
MSPEQIAAYRAIAIGNPPEAGPATEQLAELGLIEWRPHEETWVAHDPRATARGLMGEALEELAELVTRIRRVPALDALASDYDPHRMYGGPASEFLASRAAMNDRIGQVAASTSISIMTAQPGEPADRDPQIVALGVQRTIDVLHAGTEVRGLYNSLAAAHPQTAASIDAMVDAGSAARTMSGSFPRMMIFDSRHLFIDNHVVSGAEADSGWHVTDRGSVAWAVHVFDALWNRAARWSSVPVGGATTGRQRQILVELEAGYTTQQAARRLGLGERTITKELSALRSALGMRTLYQVMAWWATSPDRDLP
>NZ_CP014485.1|WP_123985165.1|6640124_6640328_+|hypothetical-protein
MSMKLRIALAAAALAAAAAVTPLATASADPAPAPPAAADDIGWGAPGKNPTPSPSPTATPAGDIGWG
>NZ_CP014485.1|WP_061405323.1|6640364_6640604_+|hypothetical-protein
MDVHLVEARLPGGVLAWADRRRTQAVMYVHPDLASGGALSAAGRHLVRESLDASVGVGWRLGGGVPDFALPGPPLSWGK
>NZ_CP014485.1|WP_061405324.1|6640971_6641985_+|alcohol-dehydrogenase-AdhP
MKAAVVRSFTEPLVVEEREVPEPAGHQVLVRMETSGLCHTDIHAAHGDWPIKPSPPFVPGHEGIGVVEARGDQVDHVQVGQRVAIPWLGEACGHCEYCVSGWETLCLQQQNSGYSVDGSHTEYALAHGTYVVPVPDGIDPLDAAPLTCAGVTTYKAVKLSGARPGKRALVSGIGGLGHLALQYATIFGAETIAVDITDEKLQLARDLGADHVVDARTQDVAEEVRRLGGADAAISLAVSNDSFRAAYDSLNRGGTLVLVALPPEGELSIPVFDTVLNGTTVTGSIVGTREDLVEVFRLHQLGRTRVVRETRRLEDINTSIDEVLDGKVTARLVFDLR
>NZ_CP014485.1|WP_061405325.1|6642005_6643997_-|hypothetical-protein
MAPLPHRPDAAPPARIGLDRAEAVVVERYARLVRLAHLVLPPALGRHRRVLLAHGVVQRALPGLTTGRGQVPVPDGSTDPVGYAWVRGQVLSAALAFEHRPRLWPRRLPPPRALRPGLPAVWGLRFFPRAGGTEELALDRVLAEVSAPARAAFALDALEELGTEDVAALLAAAGVADPEAALKEAAGVRARTGEAAGVLLASQEFDPCQVQTRPTDLLSRRRKGRLVGVGLVAVAASCALAVSGPAPAPGPEVSEADGKGGVAPVAEARGGTPALNPALLRRTDAAQWADTARVDFTAWPPRGGRTEDTELLGRALRAWSSPEAAGVKLSRSRTTPAVPPAGPPRLLYAGDVAGAAVVLLHDGSRAARYAEPLNGSSPPSLEVARTDEADVTTAAALVVSRTESGVRFLLAPWVGEAKTRDLLRPGGDARKLRVDEDGVTEAVAGPPVAGAACERWPVVRLRSSPRVVEDHAFLVTDLGELTAAHLSYTPLPGSGAGARAPREATGETALAAWARVGCRLAGLERSGVRSVNTWDFAEQTLPEEAGRAVWGCTRVSTWQGPGHVLVHLRPEAGRAAVRLVGETGPTAACSRFGQHLVASTAWRAPSGRWYSLAAGSREVRALTVSGHERERGRTAAVRTDGEPDPRVTGHLSGGDELTELEYR

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	2717253-2717272	0	1.0
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	4340836-4340855	0	1.0
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	2999245-2999273	0	1.0
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	2717104-2717123	1	0.95
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	2890353-2890372	1	0.95
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	2899387-2899406	1	0.95
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	4040913-4040932	1	0.95
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	4041524-4041543	1	0.95
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	5582500-5582519	1	0.95
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	2058736-2058764	1	0.966
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	2431746-2431774	1	0.966
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	2535001-2535029	1	0.966
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	3860570-3860598	1	0.966
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	5263184-5263212	1	0.966
NZ_CP014485_19	19.1|3503360|39|NZ_CP014485|CRISPRCasFinder	3503360-3503398	39	NZ_CP014485.1	2387120-2387158	1	0.974
NZ_CP014485_24	24.1|4002122|41|NZ_CP014485|CRISPRCasFinder	4002122-4002162	41	NZ_CP014485.1	2717248-2717288	1	0.976
NZ_CP014485_26	26.1|4513616|38|NZ_CP014485|CRISPRCasFinder	4513616-4513653	38	NZ_CP014485.1	5848210-5848247	1	0.974
NZ_CP014485_26	26.1|4513616|38|NZ_CP014485|CRISPRCasFinder	4513616-4513653	38	NZ_CP014485.1	5848273-5848310	1	0.974
NZ_CP014485_11	11.2|2553230|28|NZ_CP014485|PILER-CR	2553230-2553257	28	NZ_CP014485.1	2619864-2619891	2	0.929
NZ_CP014485_14	14.2|2998529|20|NZ_CP014485|PILER-CR	2998529-2998548	20	NZ_CP014485.1	4068784-4068803	2	0.9
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	NZ_CP014485.1	2031662-2031690	2	0.931
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	NZ_CP014485.1	4513651-4513679	2	0.931
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	3485078-3485106	2	0.931
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	4067999-4068027	2	0.931
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	4332544-4332572	2	0.931
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	6021763-6021791	2	0.931
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP014485.1	6118063-6118091	2	0.931
NZ_CP014485_19	19.1|3503360|39|NZ_CP014485|CRISPRCasFinder	3503360-3503398	39	NZ_CP014485.1	2890348-2890386	2	0.949
NZ_CP014485_19	19.1|3503360|39|NZ_CP014485|CRISPRCasFinder	3503360-3503398	39	NZ_CP014485.1	2899373-2899411	2	0.949
NZ_CP014485_19	19.1|3503360|39|NZ_CP014485|CRISPRCasFinder	3503360-3503398	39	NZ_CP014485.1	4805163-4805201	2	0.949
NZ_CP014485_22	22.1|3945035|38|NZ_CP014485|CRISPRCasFinder	3945035-3945072	38	NZ_CP014485.1	2890334-2890371	2	0.947
NZ_CP014485_22	22.1|3945035|38|NZ_CP014485|CRISPRCasFinder	3945035-3945072	38	NZ_CP014485.1	2899388-2899425	2	0.947
NZ_CP014485_24	24.1|4002122|41|NZ_CP014485|CRISPRCasFinder	4002122-4002162	41	NZ_CP014485.1	4340831-4340871	2	0.951
NZ_CP014485_24	24.1|4002122|41|NZ_CP014485|CRISPRCasFinder	4002122-4002162	41	NZ_CP014485.1	5582484-5582524	2	0.951

1. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 2717253-2717272, mismatch: 0, identity: 1.0

ttgccgggctccgtctcgac	CRISPR spacer
ttgccgggctccgtctcgac	Protospacer
********************

2. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 4340836-4340855, mismatch: 0, identity: 1.0

ttgccgggctccgtctcgac	CRISPR spacer
ttgccgggctccgtctcgac	Protospacer
********************

3. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 2999245-2999273, mismatch: 0, identity: 1.0

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccagcccggccggcgcttgaggccaccg	Protospacer
*****************************

4. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 2717104-2717123, mismatch: 1, identity: 0.95

ttgccgggctccgtctcgac	CRISPR spacer
ttgccggggtccgtctcgac	Protospacer
******** ***********

5. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 2890353-2890372, mismatch: 1, identity: 0.95

ttgccgggctccgtctcgac	CRISPR spacer
ttgccgggctccgtttcgac	Protospacer
**************.*****

6. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 2899387-2899406, mismatch: 1, identity: 0.95

ttgccgggctccgtctcgac	CRISPR spacer
ttgccgggctccgtttcgac	Protospacer
**************.*****

7. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 4040913-4040932, mismatch: 1, identity: 0.95

ttgccgggctccgtctcgac	CRISPR spacer
ttgcggggctccgtctcgac	Protospacer
**** ***************

8. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 4041524-4041543, mismatch: 1, identity: 0.95

ttgccgggctccgtctcgac	CRISPR spacer
ttgccgggctccgtcccgac	Protospacer
***************.****

9. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 5582500-5582519, mismatch: 1, identity: 0.95

ttgccgggctccgtctcgac	CRISPR spacer
ttgccgggctccgtcccgac	Protospacer
***************.****

10. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 2058736-2058764, mismatch: 1, identity: 0.966

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
ccgagcccggccggcgcttgaggccaccg	Protospacer
** **************************

11. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 2431746-2431774, mismatch: 1, identity: 0.966

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
ccaagcccggccggcgcttgaggccaccg	Protospacer
** **************************

12. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 2535001-2535029, mismatch: 1, identity: 0.966

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccagcccggccggcgcttgaggccatcg	Protospacer
**************************.**

13. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 3860570-3860598, mismatch: 1, identity: 0.966

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccagcccggccggcgcttgaggccatcg	Protospacer
**************************.**

14. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 5263184-5263212, mismatch: 1, identity: 0.966

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccagcccggccggcgcttgaggccatcg	Protospacer
**************************.**

15. spacer 19.1|3503360|39|NZ_CP014485|CRISPRCasFinder matches to position: 2387120-2387158, mismatch: 1, identity: 0.974

gttgtttgccgggctccgtctcgaccgtgccggtcaaag	CRISPR spacer
gttgtgtgccgggctccgtctcgaccgtgccggtcaaag	Protospacer
***** *********************************

16. spacer 24.1|4002122|41|NZ_CP014485|CRISPRCasFinder matches to position: 2717248-2717288, mismatch: 1, identity: 0.976

atcggtgaccggcacggtcgagacggagcccggcaacccac	CRISPR spacer
atcggtgaccggcacggtcgagacggagcccggcaaccaac	Protospacer
************************************** **

17. spacer 26.1|4513616|38|NZ_CP014485|CRISPRCasFinder matches to position: 5848210-5848247, mismatch: 1, identity: 0.974

gttttggtgcggacacgtctgaccgtgccggtcaccga	CRISPR spacer
gttttggtgcggacacgtccgaccgtgccggtcaccga	Protospacer
*******************.******************

18. spacer 26.1|4513616|38|NZ_CP014485|CRISPRCasFinder matches to position: 5848273-5848310, mismatch: 1, identity: 0.974

gttttggtgcggacacgtctgaccgtgccggtcaccga	CRISPR spacer
gttttggtgcggacacgtccgaccgtgccggtcaccga	Protospacer
*******************.******************

19. spacer 11.2|2553230|28|NZ_CP014485|PILER-CR matches to position: 2619864-2619891, mismatch: 2, identity: 0.929

tcagcctggccggcgcttgaggccaagg	CRISPR spacer
tcagccgggccggcgtttgaggccaagg	Protospacer
****** ********.************

20. spacer 14.2|2998529|20|NZ_CP014485|PILER-CR matches to position: 4068784-4068803, mismatch: 2, identity: 0.9

ttgccgggctccgtctcgac	CRISPR spacer
ttgccggggtccgcctcgac	Protospacer
******** ****.******

21. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to position: 2031662-2031690, mismatch: 2, identity: 0.931

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
ctcagcccggccggcgcttgaggccatcg	Protospacer
** ***********************.**

22. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to position: 4513651-4513679, mismatch: 2, identity: 0.931

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
ctcagcccggccggcgcttgaggccatcg	Protospacer
** ***********************.**

23. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 3485078-3485106, mismatch: 2, identity: 0.931

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
ccaagcccggccggcgcttgaggccatcg	Protospacer
** ***********************.**

24. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 4067999-4068027, mismatch: 2, identity: 0.931

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccagcctggccggcgcttgaggccatcg	Protospacer
*******.******************.**

25. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 4332544-4332572, mismatch: 2, identity: 0.931

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccagcccggccggcgtttgaggccatcg	Protospacer
****************.*********.**

26. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 6021763-6021791, mismatch: 2, identity: 0.931

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
ccaagcccggccggcgcttgaggccatcg	Protospacer
** ***********************.**

27. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to position: 6118063-6118091, mismatch: 2, identity: 0.931

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccggcccggccggcgcctgaggccaccg	Protospacer
***.*************.***********

28. spacer 19.1|3503360|39|NZ_CP014485|CRISPRCasFinder matches to position: 2890348-2890386, mismatch: 2, identity: 0.949

gttgtttgccgggctccgtctcgaccgtgccggtcaaag	CRISPR spacer
gttggttgccgggctccgtttcgaccgtgccggtcaaag	Protospacer
**** **************.*******************

29. spacer 19.1|3503360|39|NZ_CP014485|CRISPRCasFinder matches to position: 2899373-2899411, mismatch: 2, identity: 0.949

gttgtttgccgggctccgtctcgaccgtgccggtcaaag	CRISPR spacer
gttggttgccgggctccgtttcgaccgtgccggtcaaag	Protospacer
**** **************.*******************

30. spacer 19.1|3503360|39|NZ_CP014485|CRISPRCasFinder matches to position: 4805163-4805201, mismatch: 2, identity: 0.949

gttgtttgccgggctccgtctcgaccgtgccggtcaaag	CRISPR spacer
gttggtcgccgggctccgtctcgaccgtgccggtcaaag	Protospacer
**** *.********************************

31. spacer 22.1|3945035|38|NZ_CP014485|CRISPRCasFinder matches to position: 2890334-2890371, mismatch: 2, identity: 0.947

tcgccggccgggctgttggttgctgggctccgtctcga	CRISPR spacer
tcgccggccgggctgttggttgccgggctccgtttcga	Protospacer
***********************.*********.****

32. spacer 22.1|3945035|38|NZ_CP014485|CRISPRCasFinder matches to position: 2899388-2899425, mismatch: 2, identity: 0.947

tcgccggccgggctgttggttgctgggctccgtctcga	CRISPR spacer
tcgccggccgggctgttggttgccgggctccgtttcga	Protospacer
***********************.*********.****

33. spacer 24.1|4002122|41|NZ_CP014485|CRISPRCasFinder matches to position: 4340831-4340871, mismatch: 2, identity: 0.951

atcggtgaccggcacggtcgagacggagcccggcaacccac	CRISPR spacer
atcagtgaccggcacggtcgagacggagcccggcaaccgac	Protospacer
***.********************************** **

34. spacer 24.1|4002122|41|NZ_CP014485|CRISPRCasFinder matches to position: 5582484-5582524, mismatch: 2, identity: 0.951

atcggtgaccggcacggtcgagacggagcccggcaacccac	CRISPR spacer
atcggtgaccggcacggtcgggacggagcccggcaaccgac	Protospacer
********************.***************** **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014485_17	17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395146-3395177	32	NC_010311	Streptomyces sp. HK1 plasmid pSHK1, complete sequence	26157-26188	1	0.969
NZ_CP014485_17	17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395146-3395177	32	NZ_CP029339	Streptomyces sp. SM17 plasmid pSM17A, complete sequence	143726-143757	1	0.969
NZ_CP014485_17	17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395146-3395177	32	NZ_CP026489	Streptomyces sp. 604F plasmid unnamed, complete sequence	45164-45195	1	0.969
NZ_CP014485_17	17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395451-3395482	32	NZ_CP009804	Streptomyces sp. FR-008 plasmid pSSFR2, complete sequence	21861-21892	1	0.969
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	40128-40159	1	0.969
NZ_CP014485_27	27.3|4648244|32|NZ_CP014485|CRISPRCasFinder	4648244-4648275	32	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	156038-156069	1	0.969
NZ_CP014485_27	27.10|4648253|31|NZ_CP014485|PILER-CR	4648253-4648283	31	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	156039-156069	1	0.968
NZ_CP014485_38	38.9|6635498|33|NZ_CP014485|PILER-CR	6635498-6635530	33	LN997845	Streptomyces reticuli genome assembly TUE45, plasmid : IV	15768-15800	1	0.97
NZ_CP014485_38	38.11|6635626|33|NZ_CP014485|PILER-CR	6635626-6635658	33	NC_019307	Streptomyces sp. W75 plasmid pCQ4, complete sequence	45421-45453	1	0.97
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NC_023316	Streptomyces sp. 14R-10 plasmid pZL1, complete sequence	10426-10457	2	0.938
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	119913-119938	2	0.923
NZ_CP014485_9	9.2|2431437|24|NZ_CP014485|PILER-CR	2431437-2431460	24	NZ_CP016084	Streptomyces sp. SAT1 plasmid unnamed4, complete sequence	71446-71469	4	0.833
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	MN945904	Mycobacterium phage Eponine, complete genome	44962-44993	4	0.875
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NC_027365	Mycobacterium virus Fionnbarth, complete genome	44360-44391	4	0.875
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NZ_CP015737	Shinella sp. HZN7 plasmid pShin-01, complete sequence	263170-263201	4	0.875
NZ_CP014485_27	27.7|4648244|36|NZ_CP014485|CRT	4648244-4648279	36	ASHF01000034	Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence	156038-156073	4	0.889
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_LR594664	Variovorax sp. RA8 plasmid 3	300388-300413	4	0.846
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	43795-43820	4	0.846
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	43794-43819	4	0.846
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	43791-43816	4	0.846
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_CP040764	Paracoccus sp. 2251 plasmid unnamed3, complete sequence	117842-117867	4	0.846
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1588501-1588526	4	0.846
NZ_CP014485_38	38.4|6635619|37|NZ_CP014485|CRISPRCasFinder	6635619-6635655	37	NC_019307	Streptomyces sp. W75 plasmid pCQ4, complete sequence	45421-45457	4	0.892
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	MH045568	Microbacterium phage Kieran, complete genome	12875-12903	5	0.828
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	MN062717	Microbacterium phage Sharkboy, complete genome	12871-12899	5	0.828
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	MT310853	Microbacterium phage AvGardian, complete genome	12858-12886	5	0.828
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NC_042099	Microbacterium phage Dismas, complete genome	12872-12900	5	0.828
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	196866-196894	5	0.828
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1616398-1616426	5	0.828
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_LT984809	Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence	115489-115514	5	0.808
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2475822-2475847	5	0.808
NZ_CP014485_38	38.2|6635498|37|NZ_CP014485|CRISPRCasFinder	6635498-6635534	37	LN997845	Streptomyces reticuli genome assembly TUE45, plasmid : IV	15768-15804	5	0.865
NZ_CP014485_38	38.6|6635498|39|NZ_CP014485|CRT	6635498-6635536	39	LN997845	Streptomyces reticuli genome assembly TUE45, plasmid : IV	15768-15806	5	0.872
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	393389-393422	6	0.824
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	JQ067089	Pseudomonas phage PaMx28, partial genome	13942-13973	6	0.812
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	547248-547279	6	0.812
NZ_CP014485_11	11.2|2553230|28|NZ_CP014485|PILER-CR	2553230-2553257	28	NZ_CP024423	Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence	205756-205783	6	0.786
NZ_CP014485_11	11.2|2553230|28|NZ_CP014485|PILER-CR	2553230-2553257	28	NZ_CP020441	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence	202726-202753	6	0.786
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP017759	Cupriavidus necator strain NH9 plasmid pENH92, complete sequence	196261-196292	6	0.812
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1489034-1489065	6	0.812
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP040821	Paraoceanicella profunda strain D4M1 plasmid pD4M1C, complete sequence	174400-174431	6	0.812
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP035001	Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence	58383-58414	6	0.812
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	5153-5184	6	0.812
NZ_CP014485_27	27.9|4648188|31|NZ_CP014485|PILER-CR	4648188-4648218	31	NZ_CP045413	Roseovarius sp. THAF8 plasmid pTHAF8_c, complete sequence	56572-56602	6	0.806
NZ_CP014485_27	27.9|4648188|31|NZ_CP014485|PILER-CR	4648188-4648218	31	NZ_CP045395	Roseovarius sp. THAF27 plasmid pTHAF27_b, complete sequence	21961-21991	6	0.806
NZ_CP014485_29	29.2|5107079|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107079-5107110	32	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	52038-52069	6	0.812
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1159510-1159535	6	0.769
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	451519-451544	6	0.769
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	MK686071	Streptomyces phage Mischief19, complete genome	15961-15986	6	0.769
NZ_CP014485_31	31.1|5132943|26|NZ_CP014485|PILER-CR	5132943-5132968	26	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1249445-1249470	6	0.769
NZ_CP014485_38	38.8|6635619|39|NZ_CP014485|CRT	6635619-6635657	39	NC_019307	Streptomyces sp. W75 plasmid pCQ4, complete sequence	45421-45459	6	0.846
NZ_CP014485_5	5.1|1491027|32|NZ_CP014485|CRISPRCasFinder	1491027-1491058	32	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	63508-63539	7	0.781
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MH509441	Mycobacterium phage Acolyte, complete genome	20801-20832	7	0.781
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	KU204984	Pseudomonas phage AAT-1, complete genome	11956-11987	7	0.781
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	869201-869232	7	0.781
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1641274-1641305	7	0.781
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	869265-869296	7	0.781
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1593159-1593190	7	0.781
NZ_CP014485_9	9.1|2431357|35|NZ_CP014485|PILER-CR	2431357-2431391	35	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1200380-1200414	7	0.8
NZ_CP014485_9	9.1|2431357|35|NZ_CP014485|PILER-CR	2431357-2431391	35	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	613150-613184	7	0.8
NZ_CP014485_11	11.2|2553230|28|NZ_CP014485|PILER-CR	2553230-2553257	28	NZ_CP025016	Rhizobium leguminosarum strain Norway plasmid pRLN4, complete sequence	281140-281167	7	0.75
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1327396-1327424	7	0.759
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	151947-151975	7	0.759
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	NZ_CP042809	Acetobacter oryzoeni strain B6 plasmid unnamed1, complete sequence	158065-158093	7	0.759
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	MH045568	Microbacterium phage Kieran, complete genome	12875-12903	7	0.759
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	MN062717	Microbacterium phage Sharkboy, complete genome	12871-12899	7	0.759
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	MT310853	Microbacterium phage AvGardian, complete genome	12858-12886	7	0.759
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	NC_042099	Microbacterium phage Dismas, complete genome	12872-12900	7	0.759
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	136750-136778	7	0.759
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	151947-151975	7	0.759
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1327396-1327424	7	0.759
NZ_CP014485_15	15.5|3138699|29|NZ_CP014485|CRISPRCasFinder	3138699-3138727	29	NZ_CP042809	Acetobacter oryzoeni strain B6 plasmid unnamed1, complete sequence	158065-158093	7	0.759
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	320881-320912	7	0.781
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	16955-16986	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP011600	Phytobacter ursingii strain CAV1151 plasmid pCAV1151-215, complete sequence	21992-22023	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NC_014842	Pantoea sp. At-9b plasmid pPAT9B05, complete sequence	84462-84493	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_AP018757	Metakosakonia sp. MRY16-398 plasmid pMRY16-398_1, complete sequence	182687-182718	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP026189	Enterobacteriaceae bacterium ENNIH2 plasmid pENT-812c, complete sequence	68210-68241	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP050082	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b4, complete sequence	449175-449206	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP050099	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b5, complete sequence	207279-207310	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NC_008384	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence	410867-410898	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP049732	Rhizobium leguminosarum strain A1 plasmid pRL11, complete sequence	395960-395991	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NC_007765	Rhizobium etli CFN 42 plasmid p42e, complete sequence	297843-297874	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP053441	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eE, complete sequence	215503-215534	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP020909	Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence	298279-298310	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP018230	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed2, complete sequence	140006-140037	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP016289	Rhizobium leguminosarum strain Vaf10 plasmid unnamed2, complete sequence	55483-55514	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NC_012858	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132502, complete sequence	185550-185581	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NC_011366	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence	249217-249248	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NC_021908	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence	304281-304312	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP048282	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248d, complete sequence	272135-272166	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	543740-543771	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP030764	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed4, complete sequence	258150-258181	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP054023	Rhizobium sp. JKLM12A2 plasmid pPR12A202, complete sequence	18631-18662	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	36782-36813	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	226990-227021	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP054033	Rhizobium sp. JKLM13E plasmid pPR13E02, complete sequence	172191-172222	7	0.781
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP053208	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1B, complete sequence	347505-347536	7	0.781
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	158706-158737	7	0.781
NZ_CP014485_17	17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395451-3395482	32	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	236641-236672	7	0.781
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NZ_CP018784	Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence	273630-273661	7	0.781
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NZ_CP040452	Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence	428382-428413	7	0.781
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	290500-290531	7	0.781
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	MH697592	Mycobacterium phage Rando14, complete genome	40781-40812	7	0.781
NZ_CP014485_27	27.1|4648122|32|NZ_CP014485|CRISPRCasFinder	4648122-4648153	32	NZ_CP016619	Microvirga ossetica strain V5/3m plasmid unnamed2, complete sequence	359435-359466	7	0.781
NZ_CP014485_27	27.2|4648183|32|NZ_CP014485|CRISPRCasFinder	4648183-4648214	32	NZ_CP045413	Roseovarius sp. THAF8 plasmid pTHAF8_c, complete sequence	56571-56602	7	0.781
NZ_CP014485_27	27.2|4648183|32|NZ_CP014485|CRISPRCasFinder	4648183-4648214	32	NZ_CP045395	Roseovarius sp. THAF27 plasmid pTHAF27_b, complete sequence	21961-21992	7	0.781
NZ_CP014485_27	27.9|4648188|31|NZ_CP014485|PILER-CR	4648188-4648218	31	NZ_CP013255	Kocuria flava strain HO-9041 plasmid 1, complete sequence	31252-31282	7	0.774
NZ_CP014485_27	27.9|4648188|31|NZ_CP014485|PILER-CR	4648188-4648218	31	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1443336-1443366	7	0.774
NZ_CP014485_29	29.1|5107018|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107018-5107049	32	NZ_CP022140	Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K plasmid unnamed1, complete sequence	56542-56573	7	0.781
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP023738	Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence	29366-29397	7	0.781
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	353708-353739	7	0.781
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	189992-190023	7	0.781
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	332938-332969	7	0.781
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP006843	Corynebacterium glyciniphilum AJ 3170 plasmid pCgly1, complete sequence	3765-3796	7	0.781
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP024891	Rhodococcus ruber strain YYL plasmid pYYL1.2, complete sequence	11840-11871	7	0.781
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP024891	Rhodococcus ruber strain YYL plasmid pYYL1.2, complete sequence	43164-43195	7	0.781
NZ_CP014485_29	29.4|5107201|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107201-5107232	32	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	845068-845099	7	0.781
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	KX241618	Xanthomonas phage Xoo-sp2, complete genome	30972-31003	7	0.781
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	568460-568491	7	0.781
NZ_CP014485_29	29.9|5107506|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107506-5107537	32	NZ_CP021372	Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence	422171-422202	7	0.781
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_LR134466	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 24, complete sequence	50204-50235	7	0.781
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	360679-360710	7	0.781
NZ_CP014485_38	38.9|6635498|33|NZ_CP014485|PILER-CR	6635498-6635530	33	NC_047861	Bordetella phage vB_BbrM_PHB04, complete genome	62667-62699	7	0.788
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	232268-232301	8	0.765
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	766701-766732	8	0.75
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	766250-766281	8	0.75
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	15412-15443	8	0.75
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	716503-716534	8	0.75
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	989502-989533	8	0.75
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	CP002153	Uncultured bacterium plasmid PSP21, complete sequence	19927-19958	8	0.75
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	350568-350599	8	0.75
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	70152-70183	8	0.75
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MT522006	Gordonia phage BBQValindra, complete genome	21484-21515	8	0.75
NZ_CP014485_15	15.3|3138584|29|NZ_CP014485|CRISPRCasFinder	3138584-3138612	29	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	136750-136778	8	0.724
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	151945-151975	8	0.742
NZ_CP014485_17	17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395146-3395177	32	NZ_CP045376	Sulfitobacter sp. THAF37 plasmid pTHAF37_d, complete sequence	54499-54530	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5807759-5807790	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	MN234216	Streptomyces phage Gilgamesh, complete genome	97607-97638	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	MN103533	Mycobacterium phage Weirdo19, complete genome	29141-29172	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NC_016115	Streptomyces pratensis ATCC 33331 plasmid pSFLA02, complete sequence	106161-106192	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP011666	Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence	74481-74512	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	408000-408031	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1945019-1945050	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP035092	Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence	552654-552685	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NC_008688	Paracoccus denitrificans PD1222 plasmid 1, complete sequence	146187-146218	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1935325-1935356	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	JN699007	Mycobacterium phage Acadian, complete genome	23632-23663	8	0.75
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	KR080199	Mycobacterium phage Baee, complete genome	23382-23413	8	0.75
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP021917	Sagittula sp. P11 plasmid unnamed4, complete sequence	31318-31349	8	0.75
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NC_014839	Pantoea sp. At-9b plasmid pPAT9B02, complete sequence	878-909	8	0.75
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP015737	Shinella sp. HZN7 plasmid pShin-01, complete sequence	311514-311545	8	0.75
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP013516	Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence	420928-420959	8	0.75
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	353820-353851	8	0.75
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP006989	Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence	378158-378189	8	0.75
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP021374	Rhizobium sp. ACO-34A plasmid pRACO34Ab, complete sequence	214507-214538	8	0.75
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP012575	Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence	15441-15472	8	0.75
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	CP048046	Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence	14997-15028	8	0.75
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP048050	Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence	101894-101925	8	0.75
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP048048	Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence	1944-1975	8	0.75
NZ_CP014485_17	17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395451-3395482	32	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	363212-363243	8	0.75
NZ_CP014485_17	17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395451-3395482	32	MT711975	Streptomyces phage Alderaan, complete genome	420-451	8	0.75
NZ_CP014485_17	17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395451-3395482	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5845792-5845823	8	0.75
NZ_CP014485_17	17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395451-3395482	32	NZ_CP011274	Planctomyces sp. SH-PL62 plasmid pPL62-1, complete sequence	76588-76619	8	0.75
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	554630-554661	8	0.75
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	714878-714909	8	0.75
NZ_CP014485_27	27.2|4648183|32|NZ_CP014485|CRISPRCasFinder	4648183-4648214	32	NZ_CP013255	Kocuria flava strain HO-9041 plasmid 1, complete sequence	31251-31282	8	0.75
NZ_CP014485_27	27.2|4648183|32|NZ_CP014485|CRISPRCasFinder	4648183-4648214	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4344513-4344544	8	0.75
NZ_CP014485_27	27.2|4648183|32|NZ_CP014485|CRISPRCasFinder	4648183-4648214	32	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1443336-1443367	8	0.75
NZ_CP014485_27	27.4|4648305|32|NZ_CP014485|CRISPRCasFinder	4648305-4648336	32	CP054922	Streptomyces sp. NA03103 plasmid unnamed2, complete sequence	16980-17011	8	0.75
NZ_CP014485_27	27.4|4648305|32|NZ_CP014485|CRISPRCasFinder	4648305-4648336	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1621088-1621119	8	0.75
NZ_CP014485_27	27.9|4648188|31|NZ_CP014485|PILER-CR	4648188-4648218	31	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4344514-4344544	8	0.742
NZ_CP014485_27	27.9|4648188|31|NZ_CP014485|PILER-CR	4648188-4648218	31	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	826203-826233	8	0.742
NZ_CP014485_27	27.9|4648188|31|NZ_CP014485|PILER-CR	4648188-4648218	31	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	103949-103979	8	0.742
NZ_CP014485_27	27.9|4648188|31|NZ_CP014485|PILER-CR	4648188-4648218	31	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	136094-136124	8	0.742
NZ_CP014485_27	27.10|4648253|31|NZ_CP014485|PILER-CR	4648253-4648283	31	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1174511-1174541	8	0.742
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NC_006362	Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence	12934-12965	8	0.75
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP026517	Deinococcus sp. NW-56 plasmid unnamed1, complete sequence	186824-186855	8	0.75
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	441463-441494	8	0.75
NZ_CP014485_29	29.6|5107323|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107323-5107354	32	MN734438	Sphingomonas phage Lucius, complete genome	29980-30011	8	0.75
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	148446-148477	8	0.75
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	NZ_CP054618	Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence	118311-118342	8	0.75
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	375423-375454	8	0.75
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	NZ_CP046575	Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence	113679-113710	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP053575	Citrobacter sp. TSA-1 plasmid unnamed2, complete sequence	33036-33067	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	MT952845	Microbacterium phage GardenState, complete genome	18584-18615	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP050105	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b6, complete sequence	330171-330202	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP025508	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvB, complete sequence	235300-235331	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	450036-450067	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP050110	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b4, complete sequence	330173-330204	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NC_004934	Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence	51967-51998	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP006370	Aureimonas sp. AU20 plasmid pAU20c, complete sequence	138813-138844	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP022667	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR2, complete sequence	402347-402378	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP054033	Rhizobium sp. JKLM13E plasmid pPR13E02, complete sequence	109417-109448	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP047184	Rathayibacter sp. VKM Ac-2801 plasmid unnamed, complete sequence	42536-42567	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	283219-283250	8	0.75
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP050087	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b5, complete sequence	235311-235342	8	0.75
NZ_CP014485_38	38.9|6635498|33|NZ_CP014485|PILER-CR	6635498-6635530	33	NZ_CP016463	Bosea sp. RAC05 plasmid pBSY19_1, complete sequence	683423-683455	8	0.758
NZ_CP014485_38	38.9|6635498|33|NZ_CP014485|PILER-CR	6635498-6635530	33	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1387674-1387706	8	0.758
NZ_CP014485_38	38.9|6635498|33|NZ_CP014485|PILER-CR	6635498-6635530	33	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	425582-425614	8	0.758
NZ_CP014485_38	38.9|6635498|33|NZ_CP014485|PILER-CR	6635498-6635530	33	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	74764-74796	8	0.758
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NZ_CP025805	Sulfitobacter sp. SK012 plasmid unnamed1, complete sequence	6300-6333	9	0.735
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NZ_CP025806	Sulfitobacter sp. SK012 plasmid unnamed3, complete sequence	101359-101392	9	0.735
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	492871-492904	9	0.735
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NZ_CP031753	Rhodobacter sphaeroides strain EBL0706 plasmid p.B, complete sequence	86056-86089	9	0.735
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP026267	Aminobacter sp. MSH1 plasmid pBAM2, complete sequence	36854-36885	9	0.719
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	180548-180579	9	0.719
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MK450430	Gordonia phage Harambe, complete genome	18863-18894	9	0.719
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MG099935	Gordonia phage Anamika, complete genome	18864-18895	9	0.719
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MK524490	Mycobacterium phage Donny, complete genome	33315-33346	9	0.719
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MK494109	Gordonia phage Lahirium, complete genome	19100-19131	9	0.719
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MK494121	Gordonia phage Nimi13, complete genome	18582-18613	9	0.719
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	JN699007	Mycobacterium phage Acadian, complete genome	33310-33341	9	0.719
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MT889381	Mycobacterium phage Suigeneris, complete genome	33315-33346	9	0.719
NZ_CP014485_9	9.1|2431357|35|NZ_CP014485|PILER-CR	2431357-2431391	35	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	845990-846024	9	0.743
NZ_CP014485_9	9.1|2431357|35|NZ_CP014485|PILER-CR	2431357-2431391	35	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	996947-996981	9	0.743
NZ_CP014485_9	9.1|2431357|35|NZ_CP014485|PILER-CR	2431357-2431391	35	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1500379-1500413	9	0.743
NZ_CP014485_9	9.1|2431357|35|NZ_CP014485|PILER-CR	2431357-2431391	35	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1500323-1500357	9	0.743
NZ_CP014485_9	9.1|2431357|35|NZ_CP014485|PILER-CR	2431357-2431391	35	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	987926-987960	9	0.743
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	MH045568	Microbacterium phage Kieran, complete genome	12875-12905	9	0.71
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	MN062717	Microbacterium phage Sharkboy, complete genome	12871-12901	9	0.71
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	MT310853	Microbacterium phage AvGardian, complete genome	12858-12888	9	0.71
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	NC_042099	Microbacterium phage Dismas, complete genome	12872-12902	9	0.71
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	246317-246347	9	0.71
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	546685-546715	9	0.71
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	220527-220558	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	MT310862	Streptomyces phage Itza, complete genome	29623-29654	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	MN062705	Streptomyces phage Celia, complete genome	29709-29740	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	MN234189	Streptomyces phage Urza, complete genome	29644-29675	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_LR594668	Variovorax sp. SRS16 plasmid 3	459207-459238	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1098772-1098803	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	CP000664	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA03, complete sequence	86705-86736	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	136886-136917	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NC_022044	Paracoccus aminophilus JCM 7686 plasmid pAMI6, complete sequence	3249-3280	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP031753	Rhodobacter sphaeroides strain EBL0706 plasmid p.B, complete sequence	100170-100201	9	0.719
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP034185	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence	379781-379812	9	0.719
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	JQ067090	UNVERIFIED: Pseudomonas phage PaMx31, partial genome	27282-27313	9	0.719
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	1067145-1067176	9	0.719
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	MH727561	Mycobacterium phage Serendipitous, complete genome	66466-66497	9	0.719
NZ_CP014485_27	27.2|4648183|32|NZ_CP014485|CRISPRCasFinder	4648183-4648214	32	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	826203-826234	9	0.719
NZ_CP014485_27	27.2|4648183|32|NZ_CP014485|CRISPRCasFinder	4648183-4648214	32	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	103949-103980	9	0.719
NZ_CP014485_27	27.2|4648183|32|NZ_CP014485|CRISPRCasFinder	4648183-4648214	32	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	136093-136124	9	0.719
NZ_CP014485_27	27.3|4648244|32|NZ_CP014485|CRISPRCasFinder	4648244-4648275	32	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1174510-1174541	9	0.719
NZ_CP014485_27	27.10|4648253|31|NZ_CP014485|PILER-CR	4648253-4648283	31	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	775935-775965	9	0.71
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	258977-259008	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	788243-788274	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	505447-505478	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP046101	Rhodococcus sp. AQ5-07 plasmid unnamed2, complete sequence	42441-42472	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	256821-256852	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	110763-110794	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	172115-172146	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NC_006910	Micromonospora rosaria strain SCC2095 plasmid pMR2, complete sequence	9877-9908	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	MK511036	Pseudomonas phage BR327, partial genome	8186-8217	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NC_027298	Pseudomonas phage LPB1, complate genome	7137-7168	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	MN369765	Microbacterium phage Zanella, complete genome	35566-35597	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	MK511018	Pseudomonas phage CF28, partial genome	8218-8249	9	0.719
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NC_026601	Pseudomonas phage vB_PaeS_PAO1_Ab30, complete genome	8191-8222	9	0.719
NZ_CP014485_29	29.4|5107201|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107201-5107232	32	NZ_CP044976	Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-1, complete sequence	257243-257274	9	0.719
NZ_CP014485_29	29.5|5107262|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107262-5107293	32	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	690674-690705	9	0.719
NZ_CP014485_29	29.6|5107323|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107323-5107354	32	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	1029217-1029248	9	0.719
NZ_CP014485_29	29.7|5107384|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107384-5107415	32	NZ_CP013345	Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence	361404-361435	9	0.719
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4697120-4697151	9	0.719
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	483775-483806	9	0.719
NZ_CP014485_29	29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107445-5107476	32	MH399779	Microbacterium phage Jacko, complete genome	19481-19512	9	0.719
NZ_CP014485_29	29.9|5107506|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107506-5107537	32	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	556099-556130	9	0.719
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1367482-1367513	9	0.719
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP049157	Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence	904635-904666	9	0.719
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	739776-739807	9	0.719
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	23620-23651	9	0.719
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	663027-663058	9	0.719
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP047177	Rathayibacter sp. VKM Ac-2759 plasmid unnamed1, complete sequence	42991-43022	9	0.719
NZ_CP014485_38	38.9|6635498|33|NZ_CP014485|PILER-CR	6635498-6635530	33	NZ_CP012899	Burkholderia sp. CCGE1001 plasmid pCCGE1001a, complete sequence	90097-90129	9	0.727
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	37139-37172	10	0.706
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NZ_CP040824	Paraoceanicella profunda strain D4M1 plasmid pD4M1F, complete sequence	80655-80688	10	0.706
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NZ_CP035513	Haematobacter massiliensis strain OT1 plasmid pOT1-3, complete sequence	245274-245307	10	0.706
NZ_CP014485_4	4.2|1481270|34|NZ_CP014485|CRISPRCasFinder	1481270-1481303	34	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1474205-1474238	10	0.706
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	377819-377850	10	0.688
NZ_CP014485_5	5.2|1491088|32|NZ_CP014485|CRISPRCasFinder	1491088-1491119	32	MN813686	Mycobacterium phage BirdsNest, complete genome	17226-17257	10	0.688
NZ_CP014485_7	7.2|2031631|34|NZ_CP014485|CRISPRCasFinder	2031631-2031664	34	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	246317-246350	10	0.706
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	NZ_CP044082	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence	189643-189673	10	0.677
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	377423-377454	10	0.688
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	586174-586205	10	0.688
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP023993	Streptomyces malaysiensis strain DSM 4137 plasmid unnamed, complete sequence	2361-2392	10	0.688
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NZ_CP040762	Paracoccus sp. 2251 plasmid unnamed2, complete sequence	129943-129974	10	0.688
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	271204-271235	10	0.688
NZ_CP014485_17	17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395268-3395299	32	NZ_CP023670	Methylomonas koyamae strain LM6 plasmid pLM6, complete sequence	103789-103820	10	0.688
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	276818-276849	10	0.688
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	1000080-1000111	10	0.688
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NC_015409	Verrucosispora maris AB-18-032 plasmid pVMKU, complete sequence	27694-27725	10	0.688
NZ_CP014485_17	17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395451-3395482	32	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	29523-29554	10	0.688
NZ_CP014485_17	17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395512-3395543	32	NZ_CP014508	Burkholderia sp. PAMC 28687 plasmid 1, complete sequence	67599-67630	10	0.688
NZ_CP014485_17	17.8|3395573|32|NZ_CP014485|CRISPRCasFinder,CRT	3395573-3395604	32	AY320035	Bacteriophage VWB, complete genome	44841-44872	10	0.688
NZ_CP014485_17	17.8|3395573|32|NZ_CP014485|CRISPRCasFinder,CRT	3395573-3395604	32	NC_005345	Streptomyces phage VWB, complete genome	44841-44872	10	0.688
NZ_CP014485_27	27.1|4648122|32|NZ_CP014485|CRISPRCasFinder	4648122-4648153	32	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	525019-525050	10	0.688
NZ_CP014485_27	27.3|4648244|32|NZ_CP014485|CRISPRCasFinder	4648244-4648275	32	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	775935-775966	10	0.688
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP015988	Sphingobium sp. EP60837 plasmid pEP1, complete sequence	229330-229361	10	0.688
NZ_CP014485_29	29.4|5107201|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107201-5107232	32	NZ_CP035000	Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence	120403-120434	10	0.688
NZ_CP014485_29	29.9|5107506|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107506-5107537	32	NC_047902	Pseudomonas phage PMBT3, complete genome	38507-38538	10	0.688
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_LR134467	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence	77007-77038	10	0.688
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	517231-517262	10	0.688
NZ_CP014485_29	29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT	5107567-5107598	32	NZ_CP016617	Microvirga ossetica strain V5/3m plasmid unnamed1, complete sequence	450497-450528	10	0.688
NZ_CP014485_17	17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395207-3395238	32	NC_008043	Ruegeria sp. TM1040 megaplasmid, complete sequence	536239-536270	11	0.656
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP051470	Rhodobacter sphaeroides strain CH10 plasmid pRspCH10A, complete sequence	49561-49592	11	0.656
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NC_011960	Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence	102389-102420	11	0.656
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP030273	Rhodobacter sphaeroides 2.4.1 plasmid pA, complete sequence	37136-37167	11	0.656
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	CP047033	Rhodobacter sphaeroides strain DSM 158 plasmid pEA, complete sequence	30817-30848	11	0.656
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NC_009040	Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence	114067-114098	11	0.656
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP015290	Rhodobacter sphaeroides strain MBTLJ-20 plasmid b, complete sequence	33932-33963	11	0.656
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP047039	Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pEA, complete sequence	30797-30828	11	0.656
NZ_CP014485_17	17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	3395390-3395421	32	NZ_CP015213	Rhodobacter sphaeroides strain MBTLJ-13 plasmid b, complete sequence	74606-74637	11	0.656
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP026215	Citrobacter sp. CFNIH10 plasmid pCIT-ce4a, complete sequence	1718-1749	11	0.656
NZ_CP014485_29	29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT	5107140-5107171	32	NZ_CP018359	Klebsiella oxytoca strain CAV1752 plasmid pCAV1752-5521, complete sequence	3032-3063	11	0.656
NZ_CP014485_38	38.2|6635498|37|NZ_CP014485|CRISPRCasFinder	6635498-6635534	37	NZ_CP016463	Bosea sp. RAC05 plasmid pBSY19_1, complete sequence	683423-683459	11	0.703
NZ_CP014485_16	16.3|3190193|31|NZ_CP014485|CRISPRCasFinder	3190193-3190223	31	NZ_CP018081	Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence	186365-186395	20	0.355

1. spacer 17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_010311 (Streptomyces sp. HK1 plasmid pSHK1, complete sequence) position: , mismatch: 1, identity: 0.969

tgctggaagcgggtgcagtcgcagctgacctg	CRISPR spacer
tgctggaagcgggtccagtcgcagctgacctg	Protospacer
************** *****************

2. spacer 17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029339 (Streptomyces sp. SM17 plasmid pSM17A, complete sequence) position: , mismatch: 1, identity: 0.969

tgctggaagcgggtgcagtcgcagctgacctg	CRISPR spacer
tgctggaagcgggtccagtcgcagctgacctg	Protospacer
************** *****************

3. spacer 17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026489 (Streptomyces sp. 604F plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.969

tgctggaagcgggtgcagtcgcagctgacctg	CRISPR spacer
tgctggaagcgggtccagtcgcagctgacctg	Protospacer
************** *****************

4. spacer 17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009804 (Streptomyces sp. FR-008 plasmid pSSFR2, complete sequence) position: , mismatch: 1, identity: 0.969

gcgttcggggcgccgtcgtacccgatggccgg	CRISPR spacer
gcgttcggcgcgccgtcgtacccgatggccgg	Protospacer
******** ***********************

5. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 1, identity: 0.969

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
tgccagccggcgacgaatccggcccaggtcag	Protospacer
*****************.**************

6. spacer 27.3|4648244|32|NZ_CP014485|CRISPRCasFinder matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 1, identity: 0.969

ccgttcgcacccatggcgatcacctgggacga	CRISPR spacer
ccgttcgcgcccatggcgatcacctgggacga	Protospacer
********.***********************

7. spacer 27.10|4648253|31|NZ_CP014485|PILER-CR matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 1, identity: 0.968

cgttcgcacccatggcgatcacctgggacga	CRISPR spacer
cgttcgcgcccatggcgatcacctgggacga	Protospacer
*******.***********************

8. spacer 38.9|6635498|33|NZ_CP014485|PILER-CR matches to LN997845 (Streptomyces reticuli genome assembly TUE45, plasmid : IV) position: , mismatch: 1, identity: 0.97

gccgagtcgctcgccgacggcgccgagaaggtc	CRISPR spacer
gccgagtcgctcgccgacggcgcggagaaggtc	Protospacer
*********************** *********

9. spacer 38.11|6635626|33|NZ_CP014485|PILER-CR matches to NC_019307 (Streptomyces sp. W75 plasmid pCQ4, complete sequence) position: , mismatch: 1, identity: 0.97

atggtgcggggcgcctcgcgggagctggaccgg	CRISPR spacer
atggtgcggggcgcctctcgggagctggaccgg	Protospacer
***************** ***************

10. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_023316 (Streptomyces sp. 14R-10 plasmid pZL1, complete sequence) position: , mismatch: 2, identity: 0.938

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
ccgggccgtcagccggcgggcacgagcgtggc	Protospacer
************************** *.***

11. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.923

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
ctggtcgagaccgagctgaccgcgaa	Protospacer
**** ****************** **

12. spacer 9.2|2431437|24|NZ_CP014485|PILER-CR matches to NZ_CP016084 (Streptomyces sp. SAT1 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.833

gctccgatgcccacgcgcacgtca	CRISPR spacer
gctccgctgcccacgcgcacgagt	Protospacer
****** **************   

13. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MN945904 (Mycobacterium phage Eponine, complete genome) position: , mismatch: 4, identity: 0.875

ccgggccgtcagccggcgggcacgagagcggc-	CRISPR spacer
ccgggccgccagccgccgggcacg-cagcggcc	Protospacer
********.****** ********  ****** 

14. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_027365 (Mycobacterium virus Fionnbarth, complete genome) position: , mismatch: 4, identity: 0.875

ccgggccgtcagccggcgggcacgagagcggc-	CRISPR spacer
ccgggccgccagccgccgggcacg-cagcggcc	Protospacer
********.****** ********  ****** 

15. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015737 (Shinella sp. HZN7 plasmid pShin-01, complete sequence) position: , mismatch: 4, identity: 0.875

tgccagccg-gcgacgaacccggcccaggtcag	CRISPR spacer
-gccagcagcgcgacgaccccggcccagggcag	Protospacer
 ****** * ******* *********** ***

16. spacer 27.7|4648244|36|NZ_CP014485|CRT matches to ASHF01000034 (Streptomyces sp. GBA 94-10 plasmid pGBA1, complete sequence, whole genome shotgun sequence) position: , mismatch: 4, identity: 0.889

ccgttcgcacccatggcgatcacctgggacgaggga	CRISPR spacer
ccgttcgcgcccatggcgatcacctgggacgagttc	Protospacer
********.************************   

17. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_LR594664 (Variovorax sp. RA8 plasmid 3) position: , mismatch: 4, identity: 0.846

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
atgggcgagaccgagctgagcgccgg	Protospacer
 ****************** ****..

18. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 4, identity: 0.846

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
ctgggcgaggccgagctgaacgccct	Protospacer
*********.********* ****  

19. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 4, identity: 0.846

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
ctgggcgaggccgagctgaacgccct	Protospacer
*********.********* ****  

20. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 4, identity: 0.846

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
ctgggcgaggccgagctgaacgccct	Protospacer
*********.********* ****  

21. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_CP040764 (Paracoccus sp. 2251 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.846

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
ctgggcgagaccgcgctgaccctgaa	Protospacer
************* ******* . **

22. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 4, identity: 0.846

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
ctgggcgaggccaagctgaccgcgca	Protospacer
*********.**.**********  *

23. spacer 38.4|6635619|37|NZ_CP014485|CRISPRCasFinder matches to NC_019307 (Streptomyces sp. W75 plasmid pCQ4, complete sequence) position: , mismatch: 4, identity: 0.892

atggtgcggggcgcctcgcgggagctggaccggggac	CRISPR spacer
atggtgcggggcgcctctcgggagctggaccggttcc	Protospacer
***************** ***************   *

24. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to MH045568 (Microbacterium phage Kieran, complete genome) position: , mismatch: 5, identity: 0.828

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
acccgcccggccggcgcatgaggccgtcg	Protospacer
 ** ************* *******..**

25. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to MN062717 (Microbacterium phage Sharkboy, complete genome) position: , mismatch: 5, identity: 0.828

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
acccgcccggccggcgcatgaggccgtcg	Protospacer
 ** ************* *******..**

26. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to MT310853 (Microbacterium phage AvGardian, complete genome) position: , mismatch: 5, identity: 0.828

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
acccgcccggccggcgcatgaggccgtcg	Protospacer
 ** ************* *******..**

27. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to NC_042099 (Microbacterium phage Dismas, complete genome) position: , mismatch: 5, identity: 0.828

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
acccgcccggccggcgcatgaggccgtcg	Protospacer
 ** ************* *******..**

28. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 5, identity: 0.828

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccagctcgcccggcgcttgaggtcctcg	Protospacer
******.** *************.* .**

29. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 5, identity: 0.828

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cccagctcgcccggcgcttgaggtcctcg	Protospacer
******.** *************.* .**

30. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_LT984809 (Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence) position: , mismatch: 5, identity: 0.808

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
aaccgcgagatcgagctgaccgccaa	Protospacer
    ******.***************

31. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.808

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
aagggcgagaccgagctgaccccgga	Protospacer
  ******************* * .*

32. spacer 38.2|6635498|37|NZ_CP014485|CRISPRCasFinder matches to LN997845 (Streptomyces reticuli genome assembly TUE45, plasmid : IV) position: , mismatch: 5, identity: 0.865

gccgagtcgctcgccgacggcgccgagaaggtcggac	CRISPR spacer
gccgagtcgctcgccgacggcgcggagaaggtcttcg	Protospacer
*********************** *********    

33. spacer 38.6|6635498|39|NZ_CP014485|CRT matches to LN997845 (Streptomyces reticuli genome assembly TUE45, plasmid : IV) position: , mismatch: 5, identity: 0.872

gccgagtcgctcgccgacggcgccgagaagg---tcggacca	CRISPR spacer
gccgagtcgctcgccgacggcgcggagaaggtcttcggg---	Protospacer
*********************** *******   ****.   

34. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.824

-gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
ggctccagc-gggcgcggggcggcgagatcgagcc	Protospacer
 ** .*.** ***************.****** **

35. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to JQ067089 (Pseudomonas phage PaMx28, partial genome) position: , mismatch: 6, identity: 0.812

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
gaagccgagcgcgaggctcagcgtctcgccgg	Protospacer
 * * ******************.****.* *

36. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

cacgacgagcgcgaggctcagcgcctcgtctg--	CRISPR spacer
cgcgccgagcgcgaggcgcagcgc--cgtccgcc	Protospacer
*.** ************ ******  ****.*  

37. spacer 11.2|2553230|28|NZ_CP014485|PILER-CR matches to NZ_CP024423 (Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence) position: , mismatch: 6, identity: 0.786

tcagcctggccggcgcttgaggccaagg	CRISPR spacer
ggcccctggcgggcgcttgcggccaagg	Protospacer
    ****** ******** ********

38. spacer 11.2|2553230|28|NZ_CP014485|PILER-CR matches to NZ_CP020441 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

tcagcctggccggcgcttgaggccaagg	CRISPR spacer
ggcccctggcgggcgcttgcggccaagg	Protospacer
    ****** ******** ********

39. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017759 (Cupriavidus necator strain NH9 plasmid pENH92, complete sequence) position: , mismatch: 6, identity: 0.812

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
cgcgacggggccgaggcccgcgccgagcaggt	Protospacer
..***  *********************.* *

40. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 6, identity: 0.812

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
aacgaactggccgagacccgcgccgatctgct	Protospacer
 ****** *******.********** * *.*

41. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040821 (Paraoceanicella profunda strain D4M1 plasmid pD4M1C, complete sequence) position: , mismatch: 6, identity: 0.812

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcggcggcggtgatgccggtggagggcagggt	Protospacer
********  **************** * * .

42. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035001 (Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence) position: , mismatch: 6, identity: 0.812

tcggcggccttgatgccggtgga-ggggacgcc	CRISPR spacer
tcggcggcattgatgccggttgatacgggcgc-	Protospacer
******** *********** ** . **.*** 

43. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.812

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
tgccagccggtgaggaacccggcctgcgtgag	Protospacer
**********.** **********.. ** **

44. spacer 27.9|4648188|31|NZ_CP014485|PILER-CR matches to NZ_CP045413 (Roseovarius sp. THAF8 plasmid pTHAF8_c, complete sequence) position: , mismatch: 6, identity: 0.806

agttggggtcgaggtcgcagatgttgacgcc-	CRISPR spacer
ccttggggtcgaggtggtagatgttg-cgctg	Protospacer
  ************* *.******** ***. 

45. spacer 27.9|4648188|31|NZ_CP014485|PILER-CR matches to NZ_CP045395 (Roseovarius sp. THAF27 plasmid pTHAF27_b, complete sequence) position: , mismatch: 6, identity: 0.806

agttggggtcgaggtcgcagatgttgacgcc-	CRISPR spacer
ccttggggtcgaggtggtagatgttg-cgctg	Protospacer
  ************* *.******** ***. 

46. spacer 29.2|5107079|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 6, identity: 0.812

ctcggccggtgcccccgcgtccaggccgccgg	CRISPR spacer
cccggccgctgcccccgcgtcccggcccgccg	Protospacer
*.****** ************* ****  * *

47. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.769

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
tctggcgagcccgagctgaccgccgg	Protospacer
.. ****** **************..

48. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 6, identity: 0.769

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
gtcaccgagaccgagctgaccgcctc	Protospacer
 * . *******************  

49. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to MK686071 (Streptomyces phage Mischief19, complete genome) position: , mismatch: 6, identity: 0.769

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
gagggcgagaccgaggtgaccgcgtc	Protospacer
  ************* *******   

50. spacer 31.1|5132943|26|NZ_CP014485|PILER-CR matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 6, identity: 0.769

ctgggcgagaccgagctgaccgccaa	CRISPR spacer
tctggcgagcccgagctgaccgccgg	Protospacer
.. ****** **************..

51. spacer 38.8|6635619|39|NZ_CP014485|CRT matches to NC_019307 (Streptomyces sp. W75 plasmid pCQ4, complete sequence) position: , mismatch: 6, identity: 0.846

atggtgcggggcgcctcgcgggagctggaccggggacca	CRISPR spacer
atggtgcggggcgcctctcgggagctggaccggttcctg	Protospacer
***************** ***************   *..

52. spacer 5.1|1491027|32|NZ_CP014485|CRISPRCasFinder matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 7, identity: 0.781

aagccgacccagctcatgctctacggcaagac	CRISPR spacer
aaaacggcccagctcatgctcttcggcatgct	Protospacer
**. **.*************** ***** * .

53. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MH509441 (Mycobacterium phage Acolyte, complete genome) position: , mismatch: 7, identity: 0.781

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cgcgccaagcgcgaggctcagcgcctcgctgc	Protospacer
*.** *.*********************..  

54. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to KU204984 (Pseudomonas phage AAT-1, complete genome) position: , mismatch: 7, identity: 0.781

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
gacgccgagcgcgaggctcagcgtcttgcggg	Protospacer
 *** ******************.**.*.  *

55. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
ctggccgagcgcgaggcgcagcgcatcgacgg	Protospacer
*  * ************ ****** *** * *

56. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 7, identity: 0.781

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
ctggccgagcgcgaggcgcagcgcatcgacgg	Protospacer
*  * ************ ****** *** * *

57. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
ctggccgagcgcgaggcgcagcgcatcgacgg	Protospacer
*  * ************ ****** *** * *

58. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
ctggccgagcgcgaggcgcagcgcatcgacgg	Protospacer
*  * ************ ****** *** * *

59. spacer 9.1|2431357|35|NZ_CP014485|PILER-CR matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.8

aagggggcggcccgaccccgccgccacg--cggcctg	CRISPR spacer
gggcgggcggcccgaccccgccgccgcgctcgacc--	Protospacer
..* *********************.**  **.**  

60. spacer 9.1|2431357|35|NZ_CP014485|PILER-CR matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.8

aagggggcggcccgaccccgccgccacg--cggcctg	CRISPR spacer
gggcgggcggcccgaccccgccgccgcgctcgacc--	Protospacer
..* *********************.**  **.**  

61. spacer 11.2|2553230|28|NZ_CP014485|PILER-CR matches to NZ_CP025016 (Rhizobium leguminosarum strain Norway plasmid pRLN4, complete sequence) position: , mismatch: 7, identity: 0.75

tcagcctggccggcgcttgaggccaagg	CRISPR spacer
cacgaaaggctggcgcttgaggccaagg	Protospacer
.  *   ***.*****************

62. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 7, identity: 0.759

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
ctcgacccggtcggcgcttgaggccatga	Protospacer
** ..*****.***************. .

63. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 7, identity: 0.759

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
cgaagcccggccggcgaatgaggccatat	Protospacer
* .*************  ********.  

64. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to NZ_CP042809 (Acetobacter oryzoeni strain B6 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
cattgcccggccggtgctggaggccacac	Protospacer
*   **********.*** ********  

65. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to MH045568 (Microbacterium phage Kieran, complete genome) position: , mismatch: 7, identity: 0.759

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
acccgcccggccggcgcatgaggccgtcg	Protospacer
 .  ************* *******..**

66. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to MN062717 (Microbacterium phage Sharkboy, complete genome) position: , mismatch: 7, identity: 0.759

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
acccgcccggccggcgcatgaggccgtcg	Protospacer
 .  ************* *******..**

67. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to MT310853 (Microbacterium phage AvGardian, complete genome) position: , mismatch: 7, identity: 0.759

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
acccgcccggccggcgcatgaggccgtcg	Protospacer
 .  ************* *******..**

68. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to NC_042099 (Microbacterium phage Dismas, complete genome) position: , mismatch: 7, identity: 0.759

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
acccgcccggccggcgcatgaggccgtcg	Protospacer
 .  ************* *******..**

69. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 7, identity: 0.759

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
gctcgcccagccggcgcttgaggtcacgc	Protospacer
 *. ****.**************.***  

70. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 7, identity: 0.759

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cgaagcccggccggcgaatgaggccatat	Protospacer
*  *************  ********.  

71. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 7, identity: 0.759

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
ctcgacccggtcggcgcttgaggccatga	Protospacer
*.*..*****.***************. .

72. spacer 15.5|3138699|29|NZ_CP014485|CRISPRCasFinder matches to NZ_CP042809 (Acetobacter oryzoeni strain B6 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

cccagcccggccggcgcttgaggccaccg	CRISPR spacer
cattgcccggccggtgctggaggccacac	Protospacer
* . **********.*** ********  

73. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.781

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
cgcgaacgtgtcgaggcccgcgccgagcagca	Protospacer
..****** *.*****************.*. 

74. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 7, identity: 0.781

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gacgaactggccgcggcccgcgccgaggcgcc	Protospacer
 ****** ***** *************  *..

75. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011600 (Phytobacter ursingii strain CAV1151 plasmid pCAV1151-215, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
acggcggccctgatgccggtggaaggggattc	Protospacer
 ********.*************.***.  .*

76. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_014842 (Pantoea sp. At-9b plasmid pPAT9B05, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
acggcggcgctgatgccggtggagggggactc	Protospacer
 ******* .*****************.  .*

77. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018757 (Metakosakonia sp. MRY16-398 plasmid pMRY16-398_1, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
acggcggccctgatgccggtggaaggggattc	Protospacer
 ********.*************.***.  .*

78. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026189 (Enterobacteriaceae bacterium ENNIH2 plasmid pENT-812c, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
acggcggccctgatgccggtggaaggggattc	Protospacer
 ********.*************.***.  .*

79. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050082 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b4, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

80. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050099 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b5, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

81. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_008384 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

82. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049732 (Rhizobium leguminosarum strain A1 plasmid pRL11, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

83. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_007765 (Rhizobium etli CFN 42 plasmid p42e, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

84. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053441 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eE, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

85. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020909 (Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

86. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018230 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

87. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016289 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

88. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_012858 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132502, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

89. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_011366 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

90. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_021908 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

91. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048282 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248d, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

92. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
gcggcggccttgttgtcggtggaggcggtggc	Protospacer
 *********** **.********* *..* *

93. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030764 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

94. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054023 (Rhizobium sp. JKLM12A2 plasmid pPR12A202, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

95. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

96. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

97. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054033 (Rhizobium sp. JKLM13E plasmid pPR13E02, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

98. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053208 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1B, complete sequence) position: , mismatch: 7, identity: 0.781

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcgccttgatgccgatgaaggggacgat	Protospacer
***.. ************.**.******** .

99. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 7, identity: 0.781

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
ccgggccgtcagccggcgggctcggcggtcac	Protospacer
********************* **. .*. .*

100. spacer 17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

gcgttcggggcgccgtcgtacccgatggccgg	CRISPR spacer
ccgtgcggggcgtcgtcgtacccgaagacggt	Protospacer
 *** *******.************ *.* * 

101. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018784 (Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence) position: , mismatch: 7, identity: 0.781

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
ggccagccgacgacgaaccgggcccacttcgc	Protospacer
 ********.********* ******  **. 

102. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040452 (Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
tgccagcgggcgaccaacccggccagcaccag	Protospacer
******* ****** ********* . ..***

103. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 7, identity: 0.781

tgccagccggcgacgaacccggc---ccaggtcag	CRISPR spacer
ggccagccggcgccgaccccggccaacccggt---	Protospacer
 *********** *** ******   ** ***   

104. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MH697592 (Mycobacterium phage Rando14, complete genome) position: , mismatch: 7, identity: 0.781

tgccagccggcgacgaacccggcccaggtcag---	CRISPR spacer
tgcccggcggcgacgaacccggc---ggtgacgct	Protospacer
**** * ****************   *** *    

105. spacer 27.1|4648122|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP016619 (Microvirga ossetica strain V5/3m plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

tcgatgatgttcgtgacgaccggagcggcctc	CRISPR spacer
tcgatgtcgttcgtgacgaccggcttggcaac	Protospacer
****** .***************  .***  *

106. spacer 27.2|4648183|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP045413 (Roseovarius sp. THAF8 plasmid pTHAF8_c, complete sequence) position: , mismatch: 7, identity: 0.781

cagttggggtcgaggtcgcagatgttgacgcc-	CRISPR spacer
tccttggggtcgaggtggtagatgttg-cgctg	Protospacer
.  ************* *.******** ***. 

107. spacer 27.2|4648183|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP045395 (Roseovarius sp. THAF27 plasmid pTHAF27_b, complete sequence) position: , mismatch: 7, identity: 0.781

cagttggggtcgaggtcgcagatgttgacgcc-	CRISPR spacer
tccttggggtcgaggtggtagatgttg-cgctg	Protospacer
.  ************* *.******** ***. 

108. spacer 27.9|4648188|31|NZ_CP014485|PILER-CR matches to NZ_CP013255 (Kocuria flava strain HO-9041 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.774

agttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
cggcggggtcgaggtcgctgatggtgacggg	Protospacer
 * .************** **** *****  

109. spacer 27.9|4648188|31|NZ_CP014485|PILER-CR matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 7, identity: 0.774

agttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
ggtgggggtcgagttcgcagatgtagcgccc	Protospacer
.** ********* ********** *   **

110. spacer 29.1|5107018|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022140 (Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

gagaggcaggaagcctccccagggcccacacc--	CRISPR spacer
gagaggcaggaagcctctcccgg--cagaaccgg	Protospacer
*****************.** **  * . ***  

111. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023738 (Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence) position: , mismatch: 7, identity: 0.781

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gcgacggcgacggcgagcagcagcaggcgccg	Protospacer
.*  ****************.* *******  

112. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
acggcggcgacggcgagcagcaccaggaacag	Protospacer
**  ****************.****** .*. 

113. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
agcccggcgacggcgagcaggcccaggctctg	Protospacer
* *.****************  ****** *  

114. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 7, identity: 0.781

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gcgtcggcgacggcgggcagcaccagcccggc	Protospacer
.* ************.****.***** *  **

115. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006843 (Corynebacterium glyciniphilum AJ 3170 plasmid pCgly1, complete sequence) position: , mismatch: 7, identity: 0.781

acctcggcgacggcgagcagtaccaggcgcgc-	CRISPR spacer
gcctcggcgacggcgagcacgacc-gccacgtt	Protospacer
.******************  *** * *.**. 

116. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024891 (Rhodococcus ruber strain YYL plasmid pYYL1.2, complete sequence) position: , mismatch: 7, identity: 0.781

acctcggcgacggcgagcagtaccaggcgcgc-	CRISPR spacer
gcctcggcggcggcgagcagttccgcg-gcgtc	Protospacer
.********.*********** **. * ***. 

117. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024891 (Rhodococcus ruber strain YYL plasmid pYYL1.2, complete sequence) position: , mismatch: 7, identity: 0.781

acctcggcgacggcgagcagtaccaggcgcgc-	CRISPR spacer
gcctcggcggcggcgagcagttccgcg-gcgtc	Protospacer
.********.*********** **. * ***. 

118. spacer 29.4|5107201|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.781

tcttcgtcgtcacggccccggaag-ggccggac	CRISPR spacer
ccttcttcgtcaccgccccggaagttggcgaa-	Protospacer
.**** ******* **********  * **.* 

119. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to KX241618 (Xanthomonas phage Xoo-sp2, complete genome) position: , mismatch: 7, identity: 0.781

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
tcggcgtcatcaccgactacgaggacaagatg	Protospacer
  * ************* ******.****.* 

120. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 7, identity: 0.781

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
cggtcgtcatcaccgacaacgcggggcaagtg	Protospacer
 **.***************** ***  *.** 

121. spacer 29.9|5107506|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021372 (Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence) position: , mismatch: 7, identity: 0.781

tcgagcgccgggagatcaagatcagcggcgtc	CRISPR spacer
ccgccggccgggagatcaagatcggcgtcgtt	Protospacer
.**   *****************.*** ***.

122. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_LR134466 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 24, complete sequence) position: , mismatch: 7, identity: 0.781

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
ccttctcccagcacgtccgcgacgtcggccgg	Protospacer
 ****.****************** * . * *

123. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
acctgttccagcaggtccccgacggccagcgg	Protospacer
**.* ..****** **** *********** *

124. spacer 38.9|6635498|33|NZ_CP014485|PILER-CR matches to NC_047861 (Bordetella phage vB_BbrM_PHB04, complete genome) position: , mismatch: 7, identity: 0.788

gccgagtcgctcgccgacggcgccgagaaggtc	CRISPR spacer
gtcgcggcgctcgccgacggcgccgacgaagtt	Protospacer
*.** * ******************* .*.**.

125. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 8, identity: 0.765

--gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
aggtgctggc--ggcgcgcggcggccggatcgatcc	Protospacer
  *....***  ****** ****** **********

126. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cacgacgagcgcgaagatcagcgtcgggatcg	Protospacer
**************.* ******.*  * ..*

127. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cacgacgagcgcgaagatcagcgtcgggatcg	Protospacer
**************.* ******.*  * ..*

128. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cgccttgagcgcgaggctcagcgcaacgtcga	Protospacer
*.*  .******************  **** .

129. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cgccttgagcgcgaggctcagcgcaacgtcga	Protospacer
*.*  .******************  **** .

130. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cgccttgagcgcgaggctcagcgcaacgtcga	Protospacer
*.*  .******************  **** .

131. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to CP002153 (Uncultured bacterium plasmid PSP21, complete sequence) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cgccttgagcgcgaggctcagcgcaacgtcga	Protospacer
*.*  .******************  **** .

132. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
ttcttcgagcgcgatgcgcagcgcctcgcccg	Protospacer
. *  ********* ** **********.*.*

133. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cacgaccagcgcgaggatcagcgtcagggcca	Protospacer
****** ********* ******.*  * *..

134. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MT522006 (Gordonia phage BBQValindra, complete genome) position: , mismatch: 8, identity: 0.75

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
ggggtcgagcgcgcggcgcagcgcctcggatg	Protospacer
 . * ******** *** **********  **

135. spacer 15.3|3138584|29|NZ_CP014485|CRISPRCasFinder matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 8, identity: 0.724

ctgagcccggccggcgcttgaggccaccg	CRISPR spacer
gctcgcccagccggcgcttgaggtcacgc	Protospacer
 .  ****.**************.***  

136. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.742

aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
gccgaagcccggccggcgaatgaggccatat	Protospacer
. *  *************  ******** *.

137. spacer 17.1|3395146|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045376 (Sulfitobacter sp. THAF37 plasmid pTHAF37_d, complete sequence) position: , mismatch: 8, identity: 0.75

tgctggaagcgggtgcagtcgcagctgacctg	CRISPR spacer
tcgccgcagcggatgcagtcgccgctgaccta	Protospacer
*  . * *****.********* ********.

138. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gccgcggccgccgaggcccgcgccgaggggtt	Protospacer
  ** .   ****************** ****

139. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MN234216 (Streptomyces phage Gilgamesh, complete genome) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gacgaacgggccgaggcccgtgcagaaccccg	Protospacer
 *******************.** **.*  . 

140. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MN103533 (Mycobacterium phage Weirdo19, complete genome) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gtcgagcgggccgaggcccgcgccaaggccct	Protospacer
  ***.******************.**   .*

141. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_016115 (Streptomyces pratensis ATCC 33331 plasmid pSFLA02, complete sequence) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gacgaccaggccgaggcccgcgccgccccgga	Protospacer
 **** *.*****************  * *  

142. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011666 (Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gacgaccaggccgaggcccgcgccgccctgga	Protospacer
 **** *.*****************  * *  

143. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gacgaaccggccgaggccagcgccgccttggt	Protospacer
 ****** ********** ******  . * *

144. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
ccggaacgggccgaggcgctcgccgagatgct	Protospacer
.  ************** * *******  *.*

145. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035092 (Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgag--cggtt	CRISPR spacer
cccgaacgcgccgagacccgcgccgggatcga--	Protospacer
. ****** ******.*********.*  **.  

146. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_008688 (Paracoccus denitrificans PD1222 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgag--cggtt	CRISPR spacer
cccgaacgcgccgagacccgcgccgggatcga--	Protospacer
. ****** ******.*********.*  **.  

147. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
caggaacgtgccgaggccggcgccgacccggc	Protospacer
.* ***** ********* ******* * * .

148. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to JN699007 (Mycobacterium phage Acadian, complete genome) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gccgaacgggccgaggcctccgccggtcgcgt	Protospacer
  ****************. *****. **  *

149. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to KR080199 (Mycobacterium phage Baee, complete genome) position: , mismatch: 8, identity: 0.75

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gccgaacgggccgaggcctccgccggtcgcgt	Protospacer
  ****************. *****. **  *

150. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021917 (Sagittula sp. P11 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
cgcacggccttgttgccgggggaggggacgaa	Protospacer
.  .******** ****** **********  

151. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_014839 (Pantoea sp. At-9b plasmid pPAT9B02, complete sequence) position: , mismatch: 8, identity: 0.75

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
acggcggcgctgatgccggtggagggcgactc	Protospacer
 ******* .**************** .  .*

152. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015737 (Shinella sp. HZN7 plasmid pShin-01, complete sequence) position: , mismatch: 8, identity: 0.75

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcggcggccttgatatcggtggagccggcaag	Protospacer
**************..********  *.*.  

153. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013516 (Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence) position: , mismatch: 8, identity: 0.75

tcggcggccttgatgccggtgga-ggggacgcc	CRISPR spacer
tcggcggcgttgatgccggttgacacaggcgt-	Protospacer
******** *********** ** . .*.**. 

154. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 8, identity: 0.75

tcggcggccttgatgccggtgga-ggggacgcc	CRISPR spacer
tcggcggcgttgatgccggttgacacaggcgt-	Protospacer
******** *********** ** . .*.**. 

155. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006989 (Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence) position: , mismatch: 8, identity: 0.75

tcggcggccttgatgccggtgga-ggggacgcc	CRISPR spacer
tcggcggcgttgatgccggttgacacaggcgt-	Protospacer
******** *********** ** . .*.**. 

156. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021374 (Rhizobium sp. ACO-34A plasmid pRACO34Ab, complete sequence) position: , mismatch: 8, identity: 0.75

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
tcgatcaccttgatgccgatgaaggggacgat	Protospacer
***.. .***********.**.******** .

157. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012575 (Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence) position: , mismatch: 8, identity: 0.75

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
ccgcgccggcagccggcgggcaccctcgagga	Protospacer
*** **** **************    * ** 

158. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to CP048046 (Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence) position: , mismatch: 8, identity: 0.75

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
ccgcgccggcagccggcgggcaccctcgagga	Protospacer
*** **** **************    * ** 

159. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048050 (Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence) position: , mismatch: 8, identity: 0.75

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
ccgcgccggcagccggcgggcaccctcgagga	Protospacer
*** **** **************    * ** 

160. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048048 (Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence) position: , mismatch: 8, identity: 0.75

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
ccgcgccggcagccggcgggcaccctcgagga	Protospacer
*** **** **************    * ** 

161. spacer 17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

gcgttcggggcgccgtcgtacccgatggccgg	CRISPR spacer
aggcgcctggcgctgtcgtacccgaaggccgg	Protospacer
. *. *  *****.*********** ******

162. spacer 17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MT711975 (Streptomyces phage Alderaan, complete genome) position: , mismatch: 8, identity: 0.75

gcgttcggggcgccgtcgtacccgatggccgg	CRISPR spacer
aacttccgggcgccgtcgtacccggtgagcag	Protospacer
.  *** *****************.**. *.*

163. spacer 17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.75

gcgttcggggcgccgtcgtacccgatggccgg	CRISPR spacer
acgctgccggcgccgtcggagccgatggccgc	Protospacer
.**.*   ********** * ********** 

164. spacer 17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011274 (Planctomyces sp. SH-PL62 plasmid pPL62-1, complete sequence) position: , mismatch: 8, identity: 0.75

gcgttcggggcgccgtcgtacccgatggccgg	CRISPR spacer
tcgcgcgggacgccgtcgtagccgatgggaag	Protospacer
 **. ****.********** *******  .*

165. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
aggaagccgacgacgagcccggcccagaccgg	Protospacer
 *  *****.******.**********..*.*

166. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
tgccagccggtgacgaaccccgcgctgaaggg	Protospacer
**********.********* ** * *.  .*

167. spacer 27.2|4648183|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP013255 (Kocuria flava strain HO-9041 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

cagttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
gcggcggggtcgaggtcgctgatggtgacggg	Protospacer
  * .************** **** *****  

168. spacer 27.2|4648183|32|NZ_CP014485|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.75

cagttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
cgcgacgggtcgaggtcgcagttggtgacgac	Protospacer
*.    *************** ** ***** *

169. spacer 27.2|4648183|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 8, identity: 0.75

cagttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
aggtgggggtcgagttcgcagatgtagcgccc	Protospacer
 .** ********* ********** *   **

170. spacer 27.4|4648305|32|NZ_CP014485|CRISPRCasFinder matches to CP054922 (Streptomyces sp. NA03103 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

tcgccgagccacgaggccccctccttcacctt	CRISPR spacer
tcgcccagccacgacgccccctccggaacacc	Protospacer
***** ******** *********   ** ..

171. spacer 27.4|4648305|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.75

tcgccgagccacgaggccccctccttcacctt	CRISPR spacer
tggccgagccacgcggccgcctcctgcgtttc	Protospacer
* *********** **** ****** *...*.

172. spacer 27.9|4648188|31|NZ_CP014485|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.742

agttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
gcgacgggtcgaggtcgcagttggtgacgac	Protospacer
.    *************** ** ***** *

173. spacer 27.9|4648188|31|NZ_CP014485|PILER-CR matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 8, identity: 0.742

agttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
ggtcatggtcgaggtcgcagacgctgacgta	Protospacer
.**.. ***************.*.*****. 

174. spacer 27.9|4648188|31|NZ_CP014485|PILER-CR matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.742

agttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
gatcgtggtcgaggtcgcagacgctgacgta	Protospacer
..*.* ***************.*.*****. 

175. spacer 27.9|4648188|31|NZ_CP014485|PILER-CR matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 8, identity: 0.742

agttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
gatcgtggtcgaggtcgcagacgctgacgta	Protospacer
..*.* ***************.*.*****. 

176. spacer 27.10|4648253|31|NZ_CP014485|PILER-CR matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 8, identity: 0.742

-cgttcgcacccatggcgatcacctgggacga	CRISPR spacer
acaggc-cagccatggcgatcaccagggacag	Protospacer
 *.  * ** ************** *****..

177. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_006362 (Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence) position: , mismatch: 8, identity: 0.75

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gcgatcacgacggcgagcaggaccaggcgcac	Protospacer
.*  . .************* *********.*

178. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026517 (Deinococcus sp. NW-56 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
acctctgggacggcgagcagtacctgaactgg	Protospacer
***** * **************** *.  .* 

179. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 8, identity: 0.75

----acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
tcaaaccgt----acagcgagcagtaccaggtgcgc	Protospacer
    *** .    **.***************.****

180. spacer 29.6|5107323|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MN734438 (Sphingomonas phage Lucius, complete genome) position: , mismatch: 8, identity: 0.75

atcgtgaacgacttgcggggcttc-tgggcgcc	CRISPR spacer
gtcgtgaacgccttgcgggtcttcatggataa-	Protospacer
.********* ******** **** ***...  

181. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
acgagatcatcacccacatcgagggcaaggcc	Protospacer
* *  .******** *** ***********..

182. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054618 (Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
aggccgtcatcgccgacagcgaggagttgatg	Protospacer
***********.******.*****.   *.* 

183. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
aggcggtcatcaccgacatcgagcagcagttc	Protospacer
**** ************* **** .  ** *.

184. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046575 (Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence) position: , mismatch: 8, identity: 0.75

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
cggtcacgatgaccaacaacgagggcaaggtc	Protospacer
 **.*.. ** ***.****************.

185. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP053575 (Citrobacter sp. TSA-1 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
acgatacccagcacgcccgcggcggccagcat	Protospacer
**  . *********.*****.********  

186. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to MT952845 (Microbacterium phage GardenState, complete genome) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
ccggctcccagctcgtccgcgacgtccagcac	Protospacer
 *  *.****** *********** *****  

187. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP050105 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b6, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gcgcacgccagctcgaccgcgacggccagcgg	Protospacer
.* . * ***** ** ************** *

188. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP025508 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvB, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gcgcacgccagctcgaccgcgacggccagccg	Protospacer
.* . * ***** ** **************.*

189. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
ccatcgccaagcacgtccgcgacggcgcccgg	Protospacer
 * ** ** *****************   * *

190. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP050110 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b4, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gcgcacgccagctcgaccgcgacggccagcgg	Protospacer
.* . * ***** ** ************** *

191. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NC_004934 (Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
tccgcgaccagcacgttcgcgacgcccagcag	Protospacer
 *. *  *********.******* ***** *

192. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP006370 (Aureimonas sp. AU20 plasmid pAU20c, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacgg---ccagctg	CRISPR spacer
tcttcccgcagcacgtcggcgacgagatcgag---	Protospacer
 ****** ********* ******.   * **   

193. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP022667 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR2, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gcgcacgccagctcgaccgcgacggccagccg	Protospacer
.* . * ***** ** **************.*

194. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP054033 (Rhizobium sp. JKLM13E plasmid pPR13E02, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gcgcacgccagctcgaccgcgacggccagccg	Protospacer
.* . * ***** ** **************.*

195. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP047184 (Rathayibacter sp. VKM Ac-2801 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
ccgtccaccagctcgtccgcgacggcgcgatc	Protospacer
 * *** ***** *************  * * 

196. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
cgatcggcgagcgcatccgcgacggccagctg	Protospacer
   **  * ***.*.*****************

197. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP050087 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b5, complete sequence) position: , mismatch: 8, identity: 0.75

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gcgcacgccagctcgaccgcgacggccagccg	Protospacer
.* . * ***** ** **************.*

198. spacer 38.9|6635498|33|NZ_CP014485|PILER-CR matches to NZ_CP016463 (Bosea sp. RAC05 plasmid pBSY19_1, complete sequence) position: , mismatch: 8, identity: 0.758

gccgagtcgctcgccgacggcgccgagaaggtc	CRISPR spacer
tcaatgtcgctcgtcgacggcgccgacaaggcg	Protospacer
 * . ********.************ ****. 

199. spacer 38.9|6635498|33|NZ_CP014485|PILER-CR matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.758

gccgagtcgctcgccgacggcgccgagaaggtc	CRISPR spacer
ctcggcacgctcgccgaccgcgccgagcaggcc	Protospacer
 .**.  *********** ******** ***.*

200. spacer 38.9|6635498|33|NZ_CP014485|PILER-CR matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.758

gccgagtcgctcgccgacggcgccgagaaggtc	CRISPR spacer
ctcggcacgctcgccgaccgcgccgagcaggcc	Protospacer
 .**.  *********** ******** ***.*

201. spacer 38.9|6635498|33|NZ_CP014485|PILER-CR matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 8, identity: 0.758

gccgagtcgctcgccgacggcgccgagaaggtc	CRISPR spacer
ggtgatccgctcgccgaaggcgccgaggaggcg	Protospacer
* .** .********** *********.***. 

202. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NZ_CP025805 (Sulfitobacter sp. SK012 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
tgaaggtttgggcgcggggctgcaggatcgatcc	Protospacer
  *  * . *********** **.**********

203. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NZ_CP025806 (Sulfitobacter sp. SK012 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.735

gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
tgaaggtttgggcgcggggctgcaggatcgatcc	Protospacer
  *  * . *********** **.**********

204. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 9, identity: 0.735

gcatc-ggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
-cgtcgggcggggcggcgggcggcgggatccggtg	Protospacer
 *.** *********  ************* . . 

205. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NZ_CP031753 (Rhodobacter sphaeroides strain EBL0706 plasmid p.B, complete sequence) position: , mismatch: 9, identity: 0.735

gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
acatcgacggggcgcggggcagcggcggtcatgc	Protospacer
.*****.*************.**** . . ** *

206. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP026267 (Aminobacter sp. MSH1 plasmid pBAM2, complete sequence) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cacgacgagcgcgaggttcaccgaggcgaaca	Protospacer
****************.*** **   **  ..

207. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
gctttcgggcgcgaggcacagcgcctcgcccg	Protospacer
  .  **.********* **********.*.*

208. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MK450430 (Gordonia phage Harambe, complete genome) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cccgacgagctcgaggctaagcgccgggagct	Protospacer
* ******** ******* ******  *  . 

209. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MG099935 (Gordonia phage Anamika, complete genome) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cccgacgagctcgaggctaagcgccgggagct	Protospacer
* ******** ******* ******  *  . 

210. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MK524490 (Mycobacterium phage Donny, complete genome) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
gccggacagcgcgaggctcagcgtcgcgtcga	Protospacer
  **.  ****************.* **** .

211. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MK494109 (Gordonia phage Lahirium, complete genome) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cccgacgagctcgaggctaagcgccgggagct	Protospacer
* ******** ******* ******  *  . 

212. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MK494121 (Gordonia phage Nimi13, complete genome) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
cccgacgagctcgaggctaagcgccgggagct	Protospacer
* ******** ******* ******  *  . 

213. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to JN699007 (Mycobacterium phage Acadian, complete genome) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
gccggacagcgcgaggctcagcgtcgcgtcga	Protospacer
  **.  ****************.* **** .

214. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MT889381 (Mycobacterium phage Suigeneris, complete genome) position: , mismatch: 9, identity: 0.719

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
gccggacagcgcgaggctcagcgtcgcgtcga	Protospacer
  **.  ****************.* **** .

215. spacer 9.1|2431357|35|NZ_CP014485|PILER-CR matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

aagggggcggcccgaccccgccgccacgcggcctg	CRISPR spacer
gcaatcgcggcccgtccccgccggcacgcggccag	Protospacer
. ..  ******** ******** ********* *

216. spacer 9.1|2431357|35|NZ_CP014485|PILER-CR matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

aagggggcggcccgaccccgccgccacgcggcctg	CRISPR spacer
gcaatcgcggcccgtccccgccggcacgcggccag	Protospacer
. ..  ******** ******** ********* *

217. spacer 9.1|2431357|35|NZ_CP014485|PILER-CR matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.743

aagggggcggcccgaccccgccgccacgcggcctg	CRISPR spacer
gcaatcgcggcccgtccccgccggcacgcggccag	Protospacer
. ..  ******** ******** ********* *

218. spacer 9.1|2431357|35|NZ_CP014485|PILER-CR matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

aagggggcggcccgaccccgccgccacgcggcctg	CRISPR spacer
gcaatcgcggcccgtccccgccggcacgcggccag	Protospacer
. ..  ******** ******** ********* *

219. spacer 9.1|2431357|35|NZ_CP014485|PILER-CR matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.743

aagggggcggcccgaccccgccgccacgcggcctg	CRISPR spacer
gcaatcgcggcccgtccccgccggcacgcggccag	Protospacer
. ..  ******** ******** ********* *

220. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to MH045568 (Microbacterium phage Kieran, complete genome) position: , mismatch: 9, identity: 0.71

aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
cgacccgcccggccggcgcatgaggccgtcg	Protospacer
 . ** ************* *******.   

221. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to MN062717 (Microbacterium phage Sharkboy, complete genome) position: , mismatch: 9, identity: 0.71

aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
cgacccgcccggccggcgcatgaggccgtcg	Protospacer
 . ** ************* *******.   

222. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to MT310853 (Microbacterium phage AvGardian, complete genome) position: , mismatch: 9, identity: 0.71

aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
cgacccgcccggccggcgcatgaggccgtcg	Protospacer
 . ** ************* *******.   

223. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to NC_042099 (Microbacterium phage Dismas, complete genome) position: , mismatch: 9, identity: 0.71

aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
cgacccgcccggccggcgcatgaggccgtcg	Protospacer
 . ** ************* *******.   

224. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
ggatcaccccgcccggcgcctgaggccctgc	Protospacer
.. .** **** ***************  .*

225. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 9, identity: 0.71

aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
gcggctgcccggccggcgactgaggcgaact	Protospacer
.   * ************ ******* ** .

226. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gagatccgggccgagtcccgcgccaagcggcg	Protospacer
 * .  ********* ********.*****. 

227. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MT310862 (Streptomyces phage Itza, complete genome) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
cgggacctggccgaggcccgcgccgagtacgt	Protospacer
.. ** * *******************..  *

228. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MN062705 (Streptomyces phage Celia, complete genome) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
cgggacctggccgaggcccgcgccgagtacgt	Protospacer
.. ** * *******************..  *

229. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MN234189 (Streptomyces phage Urza, complete genome) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
cgggacctggccgaggcccgcgccgagtacgt	Protospacer
.. ** * *******************..  *

230. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594668 (Variovorax sp. SRS16 plasmid 3) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
caggaacgggccgacgccggcgccgatggcca	Protospacer
.* *********** *** *******  * . 

231. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 9, identity: 0.719

-----tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gctctcac-----tgccgaggcccgggccgagcagtt	Protospacer
     .**      *********** *******.***

232. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to CP000664 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA03, complete sequence) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
ctcgaacgggccgaggatcgcgccgttctggc	Protospacer
. ************** .*******  * * .

233. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
ctcgaacgggccgaggatcgcgccgttctggc	Protospacer
. ************** .*******  * * .

234. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_022044 (Paracoccus aminophilus JCM 7686 plasmid pAMI6, complete sequence) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
ctcgaaggggtcgaggcccgcgccgctcgcgc	Protospacer
. **** ***.**************  **  .

235. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031753 (Rhodobacter sphaeroides strain EBL0706 plasmid p.B, complete sequence) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
ctcgaacgggccgaggatcgcgccgttctggc	Protospacer
. ************** .*******  * * .

236. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034185 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gtaaaccgcgccgaggcccgcgcccagcgtgt	Protospacer
   .* ** *************** ****  *

237. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to JQ067090 (UNVERIFIED: Pseudomonas phage PaMx31, partial genome) position: , mismatch: 9, identity: 0.719

tcggcggccttgatgccggtggag----gggacgcc	CRISPR spacer
ccggcggccttggtggcggtggagccccagaa----	Protospacer
.***********.** ********    .*.*    

238. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
tgccatccggcgacgaatccggcgtgcgaatg	Protospacer
***** ***********.***** .. *   *

239. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MH727561 (Mycobacterium phage Serendipitous, complete genome) position: , mismatch: 9, identity: 0.719

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
gggtctccggcgacgaacctggccgaggtgcg	Protospacer
 * .  *************.**** ****  *

240. spacer 27.2|4648183|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 9, identity: 0.719

cagttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
aggtcatggtcgaggtcgcagacgctgacgta	Protospacer
 .**.. ***************.*.*****. 

241. spacer 27.2|4648183|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

cagttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
agatcgtggtcgaggtcgcagacgctgacgta	Protospacer
 ..*.* ***************.*.*****. 

242. spacer 27.2|4648183|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 9, identity: 0.719

cagttggggtcgaggtcgcagatgttgacgcc	CRISPR spacer
agatcgtggtcgaggtcgcagacgctgacgta	Protospacer
 ..*.* ***************.*.*****. 

243. spacer 27.3|4648244|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 9, identity: 0.719

--ccgttcgcacccatggcgatcacctgggacga	CRISPR spacer
aacaggc--cagccatggcgatcaccagggacag	Protospacer
  * * .  ** ************** *****..

244. spacer 27.10|4648253|31|NZ_CP014485|PILER-CR matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 9, identity: 0.71

cgttcgcacccatggcgatcacctgggacga	CRISPR spacer
acacggcacccatggcgatcaccagggagtt	Protospacer
   . ****************** ****   

245. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
tgacccgcgagggcgagcagtacctggcgcaa	Protospacer
   .* **** ************* *****. 

246. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
tgacccgcgagggcgagcagtacctggcgcaa	Protospacer
   .* **** ************* *****. 

247. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gcctcggcgatggcgaccagtacctccagaac	Protospacer
.*********.***** *******    * .*

248. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046101 (Rhodococcus sp. AQ5-07 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gtgatgccgacgacgagcagtaccaggggcac	Protospacer
..  .* *****.************** **.*

249. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
acgaaggcgaccgcgagcagtgccaggccgat	Protospacer
**   ****** *********.******  ..

250. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
acggcggcggcggcgagcagtgccaggacgat	Protospacer
**  *****.***********.*****   ..

251. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
acgaaggcgaccgcgagcagtgccaggccgat	Protospacer
**   ****** *********.******  ..

252. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_006910 (Micromonospora rosaria strain SCC2095 plasmid pMR2, complete sequence) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
tgcacgtcgacggcgagcaggaccagggcgac	Protospacer
  * ** ************* ******   .*

253. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MK511036 (Pseudomonas phage BR327, partial genome) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gggtcggcgacagcgaccagtaccagcagatc	Protospacer
.  ********.**** *********  *  *

254. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_027298 (Pseudomonas phage LPB1, complate genome) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gggtcggcgacagcgaccagtaccagcagatc	Protospacer
.  ********.**** *********  *  *

255. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MN369765 (Microbacterium phage Zanella, complete genome) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
tcctcggcggtggcgagcagtacctgtgggat	Protospacer
 ********..************* *  * ..

256. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MK511018 (Pseudomonas phage CF28, partial genome) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gggtcggcgacagcgaccagtaccagcagatc	Protospacer
.  ********.**** *********  *  *

257. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_026601 (Pseudomonas phage vB_PaeS_PAO1_Ab30, complete genome) position: , mismatch: 9, identity: 0.719

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
gggtcggcgacagcgaccagtaccagcagatc	Protospacer
.  ********.**** *********  *  *

258. spacer 29.4|5107201|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044976 (Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-1, complete sequence) position: , mismatch: 9, identity: 0.719

tcttcgtcgtcacggccccggaagggccggac	CRISPR spacer
acttcgtcgtcgcgggcccggaagcacttgca	Protospacer
 **********.*** ******** .*. *  

259. spacer 29.5|5107262|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 9, identity: 0.719

gtcaccggatcggatccagggtccgacgtgtt	CRISPR spacer
gtgaccggatcggatgcagggtcaccccggga	Protospacer
** ************ *******   *  *  

260. spacer 29.6|5107323|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.719

atcgtgaacgacttgcggggcttctgggcgcc	CRISPR spacer
atcgtgaacgacttgcgtgacttccgcatcga	Protospacer
***************** *.****.* ..   

261. spacer 29.7|5107384|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013345 (Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ccgagtccgaagatgattgcgacgggcgcgta	CRISPR spacer
ccatcgtcgaagatgatcgcgacgggtgcggg	Protospacer
**.   .**********.********.*** .

262. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.719

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
tgaacgtcatcaccgacgacgacggcaccgag	Protospacer
 *. *************.**** ****  *  

263. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 9, identity: 0.719

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
ggttgttcaccaccgacgacgagggcaagttc	Protospacer
.* .  ***.*******.*********** *.

264. spacer 29.8|5107445|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to MH399779 (Microbacterium phage Jacko, complete genome) position: , mismatch: 9, identity: 0.719

aggccgtcatcaccgacaacgagggcaaggtt	CRISPR spacer
gggccgacatcgccgacaacgaggacgcgaac	Protospacer
.***** ****.************.*. *. .

265. spacer 29.9|5107506|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 9, identity: 0.719

tcgagcgccgggagatcaagatcagcggcgtc	CRISPR spacer
aggagcgccgggaggtcaagatcggcttccgg	Protospacer
  ************.********.**  *   

266. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
aacgcgaccagcaccgccgcgacggccagcgc	Protospacer
* . *  *******  **************  

267. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP049157 (Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence) position: , mismatch: 9, identity: 0.719

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gtattcaccagcacgtccgcgtcgcccagcgt	Protospacer
.. *.* ************** ** *****  

268. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP049317 (Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence) position: , mismatch: 9, identity: 0.719

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gtattcaccagcacgtccgcgtcgcccagcgt	Protospacer
.. *.* ************** ** *****  

269. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 9, identity: 0.719

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
ccgtcgcccagcacgtccgcgccggcgaagcc	Protospacer
 * ** *************** **** *. . 

270. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
gcctcccccagcacctccccgacggcgcccat	Protospacer
.*.*********** *** *******   *  

271. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP047177 (Rathayibacter sp. VKM Ac-2759 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
ccgtccaccagctcgtccgcgacggcgccatc	Protospacer
 * *** ***** *************    * 

272. spacer 38.9|6635498|33|NZ_CP014485|PILER-CR matches to NZ_CP012899 (Burkholderia sp. CCGE1001 plasmid pCCGE1001a, complete sequence) position: , mismatch: 9, identity: 0.727

gccgagtcgctcgccgacggcgccgagaaggtc	CRISPR spacer
cagaagtcgctcgacgacgtcgccgagatcttc	Protospacer
   .********* ***** ********   **

273. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 10, identity: 0.706

gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
gcgagcgcggtgcgcagggcggcgggatcgccgg	Protospacer
**.   **** ****.************** .  

274. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NZ_CP040824 (Paraoceanicella profunda strain D4M1 plasmid pD4M1F, complete sequence) position: , mismatch: 10, identity: 0.706

gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
gcatcggcggcgcgccgggcggcgtggcctgggg	Protospacer
********** **** ******** *..* .   

275. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NZ_CP035513 (Haematobacter massiliensis strain OT1 plasmid pOT1-3, complete sequence) position: , mismatch: 10, identity: 0.706

gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
tcatcggcggggcggggggcgtcggctccatcgc	Protospacer
 ************* ****** ***  .*. . *

276. spacer 4.2|1481270|34|NZ_CP014485|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

gcatcggcggggcgcggggcggcgggatcgatcc	CRISPR spacer
ttttgaaggtggcgcggggcgtcgggattgatcc	Protospacer
 . * .. * *********** ******.*****

277. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 10, identity: 0.688

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
accgaggagcgcgaggcacagcgccagcttct	Protospacer
  *** *********** *******   *.. 

278. spacer 5.2|1491088|32|NZ_CP014485|CRISPRCasFinder matches to MN813686 (Mycobacterium phage BirdsNest, complete genome) position: , mismatch: 10, identity: 0.688

cacgacgagcgcgaggctcagcgcctcgtctg	CRISPR spacer
gatctggaccgcgaggctcagcgccgcgttgc	Protospacer
 *.   ** **************** ***.  

279. spacer 7.2|2031631|34|NZ_CP014485|CRISPRCasFinder matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

aactcagcccggccggcgcctgaggccacaactc	CRISPR spacer
ggatcaccccgcccggcgcctgaggccctgcccc	Protospacer
.. *** **** *************** .. *.*

280. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to NZ_CP044082 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.677

aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
gcgacagcgcggccggggcctgaggccggca	Protospacer
.   **** ******* **********..  

281. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 10, identity: 0.688

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gcaaaacgggccgaagaccgcgccgagcacgg	Protospacer
   .**********.* ***********.   

282. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gccgcacgggccgaggcccgcaccgccgtact	Protospacer
  ** ****************.***    ..*

283. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023993 (Streptomyces malaysiensis strain DSM 4137 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gctcgacgggccgaggcccgcaacgagcaggc	Protospacer
  . .****************. *****.* .

284. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040762 (Paracoccus sp. 2251 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gccaccttggccgagggccgcgccgagtggtc	Protospacer
  *.  . ******** **********.***.

285. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
agggcggcactgatgccggtggaggacggggg	Protospacer
  ****** .***************. . *  

286. spacer 17.3|3395268|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023670 (Methylomonas koyamae strain LM6 plasmid pLM6, complete sequence) position: , mismatch: 10, identity: 0.688

tcggcggccttgatgccggtggaggggacgcc	CRISPR spacer
ccggcggtctggatgccggtggagtccctgat	Protospacer
.******.** *************    .* .

287. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 10, identity: 0.688

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
gcgggcagtcagccggtgggcacggtcaatcc	Protospacer
 ***** *********.*******.  .   *

288. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 10, identity: 0.688

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
gcgggcagtcagccggtgggcacggtcaatcc	Protospacer
 ***** *********.*******.  .   *

289. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_015409 (Verrucosispora maris AB-18-032 plasmid pVMKU, complete sequence) position: , mismatch: 10, identity: 0.688

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
agaatgctccagccggcgggcaggacagcggc	Protospacer
  ..  * .************* ** ******

290. spacer 17.6|3395451|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 10, identity: 0.688

gcgttcggggcgccgtcgtacccgatggccgg	CRISPR spacer
gataacggtgcgccgtcctacccgatggtgct	Protospacer
*    *** ******** **********.   

291. spacer 17.7|3395512|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014508 (Burkholderia sp. PAMC 28687 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.688

tgccagccggcgacgaacccggcccaggtcag	CRISPR spacer
ccctcgccggcgacgcgcccggcccaggaaga	Protospacer
. *. ********** .***********  ..

292. spacer 17.8|3395573|32|NZ_CP014485|CRISPRCasFinder,CRT matches to AY320035 (Bacteriophage VWB, complete genome) position: , mismatch: 10, identity: 0.688

accatcgtggtcctgcctcgggcggtcggcgg	CRISPR spacer
cgagccggggtcctgcctcgggcgggcgggcc	Protospacer
   ..** ***************** ***   

293. spacer 17.8|3395573|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NC_005345 (Streptomyces phage VWB, complete genome) position: , mismatch: 10, identity: 0.688

accatcgtggtcctgcctcgggcggtcggcgg	CRISPR spacer
cgagccggggtcctgcctcgggcgggcgggcc	Protospacer
   ..** ***************** ***   

294. spacer 27.1|4648122|32|NZ_CP014485|CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 10, identity: 0.688

tcgatgatgttcgtgacgaccggagcggcctc	CRISPR spacer
tcgacgatgatcgtgacgaccgggacatgacg	Protospacer
****.**** *************..*.   . 

295. spacer 27.3|4648244|32|NZ_CP014485|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 10, identity: 0.688

ccgttcgcacccatggcgatcacctgggacga	CRISPR spacer
gacacggcacccatggcgatcaccagggagtt	Protospacer
    . ****************** ****   

296. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015988 (Sphingobium sp. EP60837 plasmid pEP1, complete sequence) position: , mismatch: 10, identity: 0.688

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
ggcacggcgacgccgagcagcaccagggcgat	Protospacer
. * ******** *******.******   ..

297. spacer 29.4|5107201|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035000 (Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence) position: , mismatch: 10, identity: 0.688

tcttcgtcgtcacggccccggaagggccggac	CRISPR spacer
cgctcggcgtcacggccgcggaagggcgcctg	Protospacer
. .*** ********** *********     

298. spacer 29.9|5107506|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_047902 (Pseudomonas phage PMBT3, complete genome) position: , mismatch: 10, identity: 0.688

tcgagcgccgggagatcaagatcagcggcgtc	CRISPR spacer
ctcactaccgtgagatcaagatcggcggcgag	Protospacer
.. * ..*** ************.******  

299. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_LR134467 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence) position: , mismatch: 10, identity: 0.688

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
ttgaaggtcagcacgtccgcgacggcctcctg	Protospacer
 .     .*******************  ***

300. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 10, identity: 0.688

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
cgcgggtccagggcgtccgcgacggccagcag	Protospacer
  .   .**** .***************** *

301. spacer 29.10|5107567|32|NZ_CP014485|CRISPRCasFinder,CRT matches to NZ_CP016617 (Microvirga ossetica strain V5/3m plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

acttcccccagcacgtccgcgacggccagctg	CRISPR spacer
ggaacccccaggatgtccgcgacggcctcggg	Protospacer
.   ******* *.*************    *

302. spacer 17.2|3395207|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_008043 (Ruegeria sp. TM1040 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.656

tacgaacgggccgaggcccgcgccgagcggtt	CRISPR spacer
gccgaagaggccgaggcccgcgccgccacccc	Protospacer
  **** .*****************     ..

303. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051470 (Rhodobacter sphaeroides strain CH10 plasmid pRspCH10A, complete sequence) position: , mismatch: 11, identity: 0.656

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
atcggccgtcaggcggggggcacgaggctccg	Protospacer
 . ********* *** *********. .   

304. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_011960 (Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence) position: , mismatch: 11, identity: 0.656

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
atcggccgtcaggcggggggcacgaggctccg	Protospacer
 . ********* *** *********. .   

305. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030273 (Rhodobacter sphaeroides 2.4.1 plasmid pA, complete sequence) position: , mismatch: 11, identity: 0.656

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
atcggccgtcaggcggggggcacgaggctccg	Protospacer
 . ********* *** *********. .   

306. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to CP047033 (Rhodobacter sphaeroides strain DSM 158 plasmid pEA, complete sequence) position: , mismatch: 11, identity: 0.656

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
atcggccgtcaggcggggggcacgaggctccg	Protospacer
 . ********* *** *********. .   

307. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NC_009040 (Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence) position: , mismatch: 11, identity: 0.656

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
atcggccgtcaggcggggggcacgaggctccg	Protospacer
 . ********* *** *********. .   

308. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015290 (Rhodobacter sphaeroides strain MBTLJ-20 plasmid b, complete sequence) position: , mismatch: 11, identity: 0.656

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
atcggccgtcaggcggggggcacgaggctccg	Protospacer
 . ********* *** *********. .   

309. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047039 (Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pEA, complete sequence) position: , mismatch: 11, identity: 0.656

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
atcggccgtcaggcggggggcacgaggctccg	Protospacer
 . ********* *** *********. .   

310. spacer 17.5|3395390|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015213 (Rhodobacter sphaeroides strain MBTLJ-13 plasmid b, complete sequence) position: , mismatch: 11, identity: 0.656

ccgggccgtcagccggcgggcacgagagcggc	CRISPR spacer
atcggccgtcaggcggggggcacgaggctccg	Protospacer
 . ********* *** *********. .   

311. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026215 (Citrobacter sp. CFNIH10 plasmid pCIT-ce4a, complete sequence) position: , mismatch: 11, identity: 0.656

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
cgttcggctgcggcgagcagtaccagcttact	Protospacer
  .***** .**************** .   .

312. spacer 29.3|5107140|32|NZ_CP014485|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018359 (Klebsiella oxytoca strain CAV1752 plasmid pCAV1752-5521, complete sequence) position: , mismatch: 11, identity: 0.656

acctcggcgacggcgagcagtaccaggcgcgc	CRISPR spacer
cgttcggctgcggcgagcagtaccagcttact	Protospacer
  .***** .**************** .   .

313. spacer 38.2|6635498|37|NZ_CP014485|CRISPRCasFinder matches to NZ_CP016463 (Bosea sp. RAC05 plasmid pBSY19_1, complete sequence) position: , mismatch: 11, identity: 0.703

gccgagtcgctcgccgacggcgccgagaaggtcggac	CRISPR spacer
tcaatgtcgctcgtcgacggcgccgacaaggcgacag	Protospacer
 * . ********.************ ****. . * 

314. spacer 16.3|3190193|31|NZ_CP014485|CRISPRCasFinder matches to NZ_CP018081 (Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence) position: , mismatch: 20, identity: 0.355

------------aacccagcccggccggcgcctgaggccaaac	CRISPR spacer
ggcacgcctccggcgccggccggactggcgt------------	Protospacer
            .  **.*** *.*.****.            

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	6615072 : 6655930	43	Streptomyces_phage(50.0%)	protease,capsid,terminase,portal,head	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP014485|6615072:6655930|DBSCAN-SWA
TGTGCGTGGCCCTCTCAAGATCCCCAAGCACCTTCAGGCGGTACCCGATCCGGGCGCTGCGGCGGGCACGGTCGCCGAGCGCGTCGACGCGTCGGCGCCTCCGAAGCCGCCGGGCTTCCCGGACGACCCGGAGATGGCGGCGCTGTGGGACGCGATCGTCCCCGAACTGGACCGCGCCGGGCTCCTGACCAGGGCTGATGGTCCGACGGTGGAGCTGGCTATCCGCCACTTCCTCGCGGCCCGGAAGGCGGGCAACGCGCTCCAGGCCGGCGAGGTGGTGCTGGACGACCCGGCGCACGGCGGGACGGCGAAGAAGAACCCTGCCGGCGCCGAGATGCGGTCGCAGTCCCAGCTGTTCCTGGAGTACGCCAAGCAGCTCGGCATGAGCTTCGCCGCCCGGGCACGGATGCCGGCGAAGGACGAGGCGACGGAGGTCAACCCCTTCGCCTGACATCCCGTCGGCGAGGTGCCGCTGTCCGGCGACGGGACTGAGGAGGTCTCCACCACGGGCTCCACCCGGTGTTCGTGGTGTGCGCGCAGCGTCCGGGCAGCGGCTCCTGGTCGACGGGGGTGGTCGCGGTGGCGGTGAAGCTGCCCGGGAAGCGGGAGTTGGCACGGCTGAAGCTCTCGCCGGAGGTGGCCTGGTACCTGCTGGACCGTGGGTACGAGTTGCCGAACTGCCCGCCGCAGCACAAGACCCCGGAGCCGCGCGAGGTCGAGGGCGCGTTTTTCGACCCGGCGCGCGTGGACCGGGTGGTCGACGCGTTCGCCCGCCTGCGGCACACGCAGGGCAAGTGGTCGGGGCGCCCGATCACGCTCCGCTCGTGGCAGATCGCGTACCTGATCGGCCCGACCTACGGGTGGGTGCGGCCGACGGAGGACGGCCGGACGGCTCGGATCATCCAGACCCAGTACCTGGACATCCCCCGGAAGAACGCGAAGACGACGATCGGCGGCGGGCAGTGCATCTACCTGACGTGCGCTGACGGTGAGGCCGGGGCGCAGGTGTACGCGCTGGCGACCCGCAAGGATCAGGCGCGGCTCTGCTTCGATCCGGTCCGCCTGCTGGCGGCGCACGCCCCGGACCTCAAGGGTCACGTGAAGCCGATGAAGGACAAGATCCTTCACCCGAGGTCGGGCTCGTACTTCTCGGTGATGTCGTCGGCCGGCGAGGCGATGCACGGCACCAGCCCGCATGCGGCGTTCGTGGACGAGGTGCACCTGCACAAGAGCAGGGACCTGATCGAGGCGGTGGAGACAGGCACGGGCGCCCGCGAGCAGCCGCTGATCATGTACGCCACGACGGCGGACGCGGGCAGCCCGTTCACGCCGTATGCGGAGATCCGCGAGTACTGCGAGAAGCTCGCCCGCGGCGCGCTGGTCGACCCGACGTTCTACGGCGTCGTGTTCGCTGCGGGGCGGGGCGACGACCCGTTCGCCCCGGAGACCTGGCTGAAGGCCAACCCTGGCCTGGCGGCTGGCGACTCGCCGACGATGGAGTCGATGGAGAAGGCCGCGGCCAAGGCCCGGCAGAACCCGCTGGAGCTGGCCAGCTTCCTGCGGCTGCGGCTCGGCATCCGCACGAAGCAGGAGTCGAAGTTCATCTCGCTCTCGGAGTGGGACCGGAACGCCGGGATGGTGGACCGGGCCGCGCTCCGGCGGGCGGAGTGCTACGGCGGCCTCGACCTGGCGGCCACCTCGGACCTCTCGGCCTTCTGCCTCGTCTTTCCGAACGGGCCGCCGGCCAGCGGCATTGAGGGCTATCAGGCTCTGTGGCGGCTGTGGACTCCGCAGGCGAACCTCTGGAAGCTCAACGAGCGGACGGCGGGCGCGGCGGATGTGTGGGTGCGTGAGGGCTGGCTGACGGTGACGCCGGGCGAGGTCATGGACTACGACCACATCCGGCAGGCGATCAACCAGGACCGCGAGGTCTTCAACGTCCAGGAGATCGCCTACGACCCGTGGAACTCGACGCAGCTCGTCTCGGACTTGTTGTCGGACGAGGCGCCACTGGTGGAGTTCCGGCAGGGCTACCGGTCGATGAGCCCGCCGCTGAAGGAGCTGGCCAGGCTTCTCCGCCAGGGAACGCCGGAGACGCCGTTGCTGCGGCACGGCGGGAACCCGGCGATGCGCTGGCAGATCGACAACCTCGCGGTCGTGTCCGACCCGGCGGAGAACGTCAAGCCGGACAAGAAGCACTCCGCGGACAAGATCGATGGCGTCGTCAGCTTGATCATGGCGCTGGACCGGGCCCGGAACCGGAAGCCGCTGCGGCGGAGCGCCTACGACGACGATGACGACTACGACGACGAGGCGGATGTCGCGTGACTGGGGGTGCAGCATGGGCTTCTGGTCGCGGGTGAAGTCTCTGGCGTGGTGGGGCAGCCGGCCCTCGAGCGGTTCGTGGGATCGGCGGGGCTGGTCGTGGCTGCCGCTGGATCAGTCCTACGTGCTGGGCATGGAGCCGGCGGAGCTGTGGCGGACGCAGCCGCATCTTCGGACGGTCACGGACTTCATCGCCCGGAACGTCGCCCAGCTCGGCCTGCACGCCTACGACCGGCGCGGCGACACGGACCGGCGGCGGGTTCGCGGCGAGGGTGTGGCCGCTCTGCTGCGGCGCCCGAACGCGGACATGACGACCTACGAGCTGGTCTACGGGACGGTCGCTGACCTGGCTTTGTTCGACCGGGCGTTCTGGTGGGTGAAGCGGTCGGCGTCGGCGCCGTCGGGTTGGGAGATCCGCCCGATCCCGTCGGCGTGGGTGGTGCAGGGGGTGGGCGGCACGGTGTTCGCTCCGGCGGACTGGATCGTGCAGCCGCCGCACGGCGCTGAGCAGCTGACGATCCCGGCCGCGCAGATGCTCGTCTTCCACGGCTGGAACCCGAGCGATCCGTCCGCGGGATCGTCGCCGGTGGCGGCGCTGAAGCTGATCCTGTCGGAGCAGGTGCACGCGTACCAGTACCGCGAGCAGGTGTGGCAGCGCGGCGGCCAGCCGTCCGCGGTGATCGAGCGGCCGATGGACGCTCCGCAGTGGGGCTCGAAGGGCAAGGCGCGGTTCAAGCAGGAGTGGCAGGACTCCTACGGCCGGTCGGGCCCGGAGGCGGGCGGGACGGCGATCCTCGAGGACGGCATGAAGCTGGTGAAGACCGGCTTCAGCGCGCGAGAGGACGAGTTCGTCGCGGCGGCCACCCTGAGCCTGACAACGGTGGCGTCCGTCTACCAGGTCAACCCGACGATGGTCGGTGTCCTGGACAACGCGAACTACTCGAACGTGAGGGAGTTCCGCCGGTCGCTGTACGGGGACTCGCTCGGCCCGTGGCTGACGATGCTCCAGGACCGCCTGAACGGCTTCCTGCTGCCGATGCTCGGGGAGCCTGAGGACCGGTACGTCGAGTTCAACCTCGCCGAGAAGCTGCGGGGTTCCTTCGAGGAGCAGGCGGCCGTGCTCCAGGCGAGCGTGGGCCGGCCGTGGATGACGGCGGACGAGGCGCGCGGGCTTCAGAACATGCCCGCGTTGGGCGGTGACGCCGAGGAGCTGGTGACGCCGTTGAACGTCCTCGTGGGCGGTCAGGCGTCGCCGCAGGATTCGGCCCCGCCGCCGACGCTGGCCTCGGACGCTCCGCCGCGTGAGGCGTCGGGGGCGGGGCTGGTGCGGGGAAAAGCCCGCAAGGTCCGCGCGGACCCGGTGCGGGCTGACGACTTCGAGGCCCGGTACGAGCGGGGCCTGACCCGCTGGTTCGACGACTTCACGTCAGCGGTCCTGGCTGGGTACGGCTCGGCGAAGCGGGGTCCGGTCCGAGTGAAGGCGGCCGAGGACTTCGTGGACCGGGAGGAGTGGCAAGCGTCGCTGGCGGATCTGCTGCTGACGCTGGGCCTGGCAACGTCCACGGCGGCGGCTGAGGCTCTGCTGGAGCAGGTGGGTCTGCCGCCCGAGGACTACAACGCCGAGGCGACGGTGGCGTGGCTGACGGCCATGGCCGCTGGCGTCGCCGAGGGCATCGTCGGGGCGACGCTCGCGGAGGCCGACGAGGCGCTCGCGGACGCGGAGCGGACGGACGAGGACGGCGAACCGATGCCGCCCGAGGCCCGTCTGGCGGCGGCGCTTGCGGCGGCGGCCGGGTCGCGTGTTCCGGAGATCGCTTCCAGCCAGGTGACGGCCCTGTCGGGGTTCGGCCAGGCGGAGGCGGCGCGGGGTGCGGGTGGCGGCGCGACGAAGACGTGGCGTGTCCGCTCGACGAACCCCAGGCCGGCGCATCGCCGGATGGACGGGGAGACGGTGCCGCTGGACGACCGGTTCAGCAACGGCGCCCGCTGGCCCGCGGACAGCTCGCTGGACGACGCGGACCGCGCGGGCTGCAAGTGCGCGGTGGAGATCGAGTTCGAGTTCTAGGCCCGAGGGGGCATTTGTGCAGGTCAAGGATGCACCCGCTCTGCGGGTCAAGGTCACCGAAGTCGATACCGAGGGCGGCCCTGAGGCTCCCGGTACCGGCGAGTTCACCGCGCTGGTCAGCGTGTTCGGCAACGTCGACAGCTACGGCGACGTCGTGATGCCCGGGGCGTTCGACCGGTCGCTGAAGGAGTGGTCCGCGTCGGGCTACCCGATCCCCGTGTACTGGGGTCACAACCTGAGCGACCCGGACTACAACATCGGCTCTGTCATCGACGCGGTGGAGACGGAGCGTGGGCTTCAGATCCGGGCCCGCTTGGACATGGACAGCCCGAAGGCCCCGCAGGTGTACCGCCTGTTGAAGGGCGGCAGGGTCAAGGAGTTCTCCTTCGGCTACTCGGTGCGCGACGCAGGGTGGGGCACGAAGGACGGTGCTGAGGTCTTCGAGCTGCGGGACATCGACCTCTACGAGGTGTCGGTCGTCCCGGTCGGCGCGAACCCCGCCACCGAGCTTCAGACGGTCAAGGCCCTCGGTGAGCGCACAGAGCGGGCGGCCGCCCGCGCCCTGGAGGGCGTGAAGGCGGGCCGGGCCCTGTCTGGGAAGAACGAGTCCGCGCTCCGCGAGGTGCGCGATCAGCTTGCCGTCGCGATCGAAGGGATCGACGACGTGCTGTCCGCCCTCGATCCGCCGGAGTCTCCGGCCGAGGACGAGGACGACGAGAAGAAGAGCCAGGAAGAGGACCCGGCCACGGAGCGGGAGCCGGCCGACGACGAGGAGCCCGACGGGGCCAAGTCGATCGAGCCCATGCCCGACTTCGCCGCCGACCCACTGGCGGCCATCATCGAGATCGAGACGAGGAGTGCGCAGGCATGAACCTGCACGAGCAGCGCCAGACGGCGCTCAAGGCCGCCCGGGACGTGGCGGAGAAGGCCCGCGACGAGGGCCGTGTCCTGACCGAGGACGAGCAGACGACGGTGAAGGGCCACCTGGCGACCGCCGACGACTGCGCCGAGAAGATCAAGCAGGCGGCCGAGTCGGACGCCCTGTTCAAGCGGGCGTTCGCCGTCGAGGACGGGAAGCCGTCCGGGGGCGGCTCCGCGCCGGTCGGCGTGAAGGCCAAGCTGGAGGCGGACGCCGCGTACAAGAGCGCGACGCTCGCGGCGTCCTCCCGCACGAGGTTCTCCCAGCGGACCACCGAGTTCGAGGCGAAGGACTTCTCGACCGGCGGCCCGGCGGGCGGGCTGGTGCAGACCCAGTACGGGCAGGTCGTGCCGGAGACGCTGCGGCGTCCGACGGTCGCCCAGCTGCTGGGCTCCGGCACCATGTCGGCGACGACCCTCACGTACTACGTGCAGGGCCCGAGCGCTGGCGATTTCGCGGTGGTCCCGGAGCTGGGCGAGAAGCCCGCGATCGACTTCGACTTCGAGCCCGAGGTCGAGACCCTGTCGAAGATCGCCGGAATCACGAAGATCAGCGACGAGGCGTTCCAGGACACCGCGTACCTGGTCAGCGTCATCGAGTCGCAGATGCGTCTGCGGCTGGTGCTGGCCGAGGAGGCGCAGCTCCTCAACGGCACCGGCACGGGCGGCAACATGACGGGCCTGCTCAACCGGTCCGGCATCCTCACCGAGGCGAGCGCCAGCGCCGACGACGACCTGGACGCCATCTTCCGCGGCATGACCGCCGTGGAGCTGGCTACGCAGCTGCCGGTCGACGCGGTCGTCATCAACCCGCTCGACTACCAGCGCCTCCGCCTGTCCCGTGACGCGAACGAGCAGTACTTCGCGGGCGGCCCGTTCACCGGCGCCTACGGCAACAACGGCATCCAGATGTCCCCGGGCGTGTGGGGCCAGAACACGGTCGTCACCTCGGCCATCGCGCAGGGCACGGTCCTGGTCGGTGCGTTCGCGGTCGGCGGCCAGGTGCTCCGCAAGGGCGGCGTCTCCGTCGAGATGACCAACAGCGACGCGGACGACTTCCGGCACAACCGGGTCGCGATCCGCGTGGAGGAGCGCCTGATGCTGGCGGTCTACCAGCCGTCCGCGTTCTGCGAGGTCACCCTCTTCGCGGAGGACGAGGGCGGCGCCTGAACCGCCTGGTCGTAGCAGTCCACGGGCCCGGCCGCGTTCGGCCGGGCCCGCCTCACAGACAAGGAGAAGGCCGTGGCACGGCTGGAAGAGTACGAGGTCGACATCGCCTCGGGCGTGACGGTGACGATGAAGCTGTCCCCGGACGCCGCGGAGAAGGCGGACCCGAAGCGGGTCCGGAAGGTCACGCGGGCGAAGGGCCGCCCGGTGGCGAACAAGGTGCGCCGCCCGGCGAACAAGTCGGCGACGTCGGAGAGCTGATCTCGGCGAGGAGGTCGTGATGGCTGCTCTGGTGGAGCTACTGGATCGGCTGAGGCGCCGTCCGGGCATGGCTGATCTGACGGAGCAGGAGGCGGACGATCTCCTCGCCGAGGCGGCGGAGATGGTGCACGACTACTGCGGCTGGCGGGTGTGGCCTCGGCTGGTGGAGACCATAACGGTGGATGCGGTGGGCGGGGCTGTGGCGGGCCTGCCCACGATGATGCTGCACGAGGTGTCCTCGGTGGAGACCCGCCCGCCGGCCGCGACCGGCCCGGATGCGTGGGAGCCGGTGGCGGGCGGCTGGGACTGGTCGGAGGGCGGCTGGTTGTACCGGTGCGGCCGCTGGCCGGACGGCCCCCGTCGGCTGCGGGTCGTCATGGAGTCGGGCTACATGGAGCCTCCGGGCGCGGTCGGCAGCGTGATGCTGGGGATCGCGGCCCGGGTGCGGACAGCGCCGGTGGGTGTGTCGTCGGAGCAGGCGGGCGGCGAGTCCGTCTCCTACGGCACGTCGGGCGCCTCGACGGACTCGGGCGCGGGCGGCCAGCTCACGGAGGCTGAGCGTCGGGTCCTGGACCGCTACCGGCTGGAGAACCGGCCATGAGCTTCGGGTGGCACCGGGACACGATCGTGCGAGTGCGGGCCCCGCTGACGACCGACCCCTACGGCAATCCGCGCCGGGACTGGGCGGCGGCCGAGCGCACCTCGATGCCGGGCTGGCGGGTTCAGCCGGTGCAGGGCGCCCGCCAGACGGCTGCCGAGACGATCCCCCGCGAGGGGCTCGAGCGGTCAAAGCGTCTGTTCGGCCCGATCTCTGCGGACATCGAGTCGACGGACCGGATCGAGTGGCAGGGCGAGGTGTGGGTGATCGACGGCGACGTCGACCGCTGGCGCGGCCCGACCGGCCGGCTCGCTCACACGGAGCTGCTGATGCAGCGGATGGAGGGCTGATCATGGCGCGCGCACGAGTTCGGGTGGAGATCAACTACGACGGGATCGGCGAGCTGGCCCGCTCCGGCGGGGTCCGGGCGGACCTCGAGCGGCGGGCGCAGGCGGTCCGCGCGGCCGCCCAGGCGGCGGCCCCCCGCATGCAGGAGGGCCGGATCGAGATCGAGGCGTCGACCCGCGTCGGCCGGGACCGCGCCCGCGGCATCGTCGTGGCGCAGCACCCGGGCGTGCTGCACGCGGAGGCGAAGCACCGGTTCCTCGGCGGCGCGATGGACGCGGCGGGCGACTGATGGCCGCCCCGGTGGTGGCGTGGCCGGACGTCACGCTGCTGGCCACGCAGTACCTGCGGGACCGGCTCGGCGGCGTCCAGGTCGGCTCCCGCATCCCGCGCCCGCGGCCGGTCGAGTTCGTGGTGCTGCGGCGCGTAGGCGGCCCTCGGCGGAACCCGCTGGTGGACGACGCCCGCCTCGACGTGCAGGTGTGGGCGGAGACGGACGAGCGGGCGATGGAGATCGCCAGCCTCGCCCGGTACCAGCTCGGCCTGATGCCGCAGCATGTCCCGGCGGTCCGCCAGTTCGGTGAGGACGCCGGCCCCAACCTGATCCCCGACGCACCCTCGGATGTCCCGCGGGTGCTGCTGACGGTAGTTCTGTCGGTCCGCGGCGCGGTCCCGACCTAAGAGAAGGAGAGTGCGCCGTGGCGAAGGATACGGCGAACGCAAGGGCGTGGTACGGCTTCGACTCCGGGCTGTGGGTGACCCTGCCCGGGGAGCCGATGCCCGACCTCGACGAGATCCCCGACGTCTACGACGAGGCTGGCGTCTTCCAGCCGCCCGGCGAGGCGTTCTACGAGGTGGGCTGGCTGTCCGAGGACGGCCCCACCCAGGGCCGCAACCGCACGGTCGAGCGCTTCCGCGGCTGGCAGGGCAACTCGATCGTGAGGACGGCCGTCACGGAGGACGACCACACCTTCCAGATCCAGGCCCTGGAGGACAACTGGGTGGTGGCCAGCCTCCGGTACCCGGACTCGGTGGTCACCACAACGGCGGGCATCACGAAGACGGTGGTGCAGCAGCAGTCCGGCGAGGACGTGCGTACCGGCGTCCTCGACCTGGTCGACGGCGGCATCTGGAAGCGCATCCTCATCCCGAACCTCGTCGTGGACGAGATGGGCGACACGTCGCACACGGCCGGTGAGCTGACGTTCTACGAGATGACGCTGCTCGCCAAGGTCACCTCCCTGTCGGTCGACGGCGTGGTCCGCGGCGTCAGCCTCATCGAGGTCACCAACAACCCGGCGGCGATCCGGCCGACGGTCCCCGACCCCACCCCCTGATCCACCCCTGACCGGGGCGCCCCCGCCATGCGCGGTCCGGGGGCGCCCCTTCCCTTTCCACGACCGCGCGCAGGGAGAGACCGCGCATGAGCCACGGGAAGACCACGTTCGACCTCGCCGAGCTGCGGCAGCGCGCCGCACAGCGCAAGGGCGGCGACAAGCTGACCATCACCATCGACGGCAAGCCGTACACGATCCCGGTGCCCGGCTTCTGGCCGGACCGGGTCAAGGAGCTGGCCCGCCGTAGCCGAGAGGACGGCGACGTCCCCTTCGTCCGCGAGCTGATGGGCGCCGAGAAGTACGAGAAGTTCGTGGCGGCGGGCGGCCGGTCGGACGACGTGGCACTCCTGCTGGAGGAGTACAAGCAGGCCCAGGGTGCTGACCTGGGGGAATCTTCGCCCTCGCCGACCTCCTGAGTGAGTACGGCGGGGAGATAGAGCACGACCTCCTCCTGATGGGCTTGGACCTGGACGACATCGGCGCACCGCACCTCACGTGGGGGCGGCTGTGGCGGCTCGTCCAGGTCATCCCGAAGACGTCCCGCAGCGCGCTGGCGTGGGCGAAGTCCCGCGAGTCCGGCGTGTACCCGCTCGACATCGAGCTGGCCGCCGGGCACTTCGACGCCCTGTCGGTGGCGAACTGGCAGCGGTCGAAGAAGGCCAGCAGCGCGGGCAGCGCCCCGAAGCCGCTGCCGCGCCCCAGCAAGATCGAGGCGACGCGCGGCGAGGCCCGCGACCGGCTGATCGACCGCGGTCGGGCTCTGCTCCGGCGCCAGCGGCCAAGACCGAAACCCCGAACCAGCTGACGAGACGGGGGTGGTCGTCGTGGCCGGTGGGCCTCAGGTCGGTACCGCATGGGTGCAGATCACCCCCAGCTTCCAGGGCTTCGGCTCCAACATCATGTCGGAGGTCGGCCGCGAGCTGTCCTCCGGCGCGGGCCGCGCGGGCGAGCAGGCCGGCGAGGCGGCCGGGCGCGAGTTCGGCTCCTCCTTCGAGGAGCGTGCGTCTGCGGCGGCGGAGCGCATGGGCCCGATCGGCACGGCGGCTGGCGTCGGCATCGCCGGTGCGCTGGGCGTGGGCCTGGCCGCCGCCATGGACGCCTCGTCGGCCACCGCCAAGCTCACGGCCCAGCTGGGCCTGACGGAGGCGGAGGCGGCCCGGGTCGGCGCCATCTCCGGCGAGGTCTTCTCTGCCGGGTTCGGCGAGTCGATGGGCGAGGTGTCCGAGGCCGTCGGCGCGGTCACCTCCTCTGTGGCCGACCTCGGCGCCACCTCGGACGCGGAGCTTCAGCAGCTCACCACGACCGCGCTCGGCCTCGCGGAGACGTTCCAGTGGGACGTCGGCGAGGCCGCCACCGCGGCGGGCAACCTCGTCAAGAACGGCCTGGCGAAGGACGCGACCGACGCGTTCGACGTCATGTCGCAGGCGGCGAAGACGCTGCCCGCGAGCATGCGCGCCGACATCCCCGCCGTGGTGTCGGAGTACGGCATTCACTTCGCCCGCATCGGCCTCGACGCGAAGACGGCGTTCGGGATGATGTCGCAGTACGTCGAGGCGGGCGGCCGCGACATCGACCAGGCCGCGGACGTCCTCCACGAGTTCGGGCGGATCACGTCCGAGGAGACCGACCGGGCGGCCGAGGGCTTCAAGGCGCTGGGGCTGGACTCCAGCCAGATGCTCTCCGACATCGCGAAGGGCGGCGAGCCGGCCGAGGCCGCGCTCACGGCGACCCTCGACGCGCTGCGCGGAGTGAAGGACCCGGCCGAGCAGAGCGCCCTCGCGGTCGAGCTGTTCGGCGACATGGCCGGTGAGGGCGTCGATGCCCTGTGGGCGATGGACCCGGCAACCGCTGCCGCCGCGTCCGGCATGGACAAAACGGCCGGCTCCGGCAAGGAGCTGACGGACGCGCTCGCGGCGGACCCGGCGCGGGTCTTCGAGGGCGCGATGCGGGACCTGACAATGTCCCTCGCGCAGGAGTTGGCGCCCGCGCTGGCGGGCGTTGCCGGCTGGGTGTCAGACAACGAGGGTGCGTTCAAGGGCATCGTCTTCGCCGTCGGCGGGATCGCGCTGGCGGTGGCCGGGGCGACGGCCGCGCTGCGCCTGTACCAGGGCGCGATCGTCGCGGTGCGCGTCGCGACGGCGATCTGGACCGGGATTCAGTGGCTGCTCAACGCGGCGTTCTGGGCGAACCCCATGACGTGGGTGGTCCTCGGCATCATCGCCCTGATCGCGATCATCGTGCTGGCGATCGTCTACTGGAACGAGATCGTCGCCGCTGTCCGCGCCGCCTGGCAGTGGATCACCGAGGCCACCGGTGTCGCGGTCGAGTGGCTGAAGGTCAAGCTCGGCGAGGCGTGGGAGTGGATCAAGACCACGGCCAGCGCCGCCTGGGAAGCCGTGAAGGCGACCATCGGCGGCGCCTGGCAGTGGATCAAGGACCAGACGGGCGCGGCCGTCGACTGGGTCGCCACCAAGGCCGCAGCTGCCTGGGAAGGCATCAAGGGGGCCGCGAAGGCGGCGTGGGACGGGGTCGTCCTGATCCTCAAGCTGGCCTGGGCCACCATCGTCCAGATCGCTGCCGGTGCGGTCCTCGGGCTCATCACCGCGATCTCGGGCGCCTGGTCGACGATCAAGCGCGCCACCTCTACCGCGTGGGCCACGGTGAAGCGGTCCATCACAGACGCGGTCGGCCGCGCATACGACTCGGTGAAGAACGCCGGGTCCCGCTTCCTCAGCGTCGGCCGGGACATCGTCAACGGCATCGTCACCGGGGTCCGCAACGCCGCCGGGCGCCTCTTCGGTAGCTTGCGAGACATGGCGTCGAATGCCCTGTCGGCAGCGAAGAACGCCCTCGGCATCGGCAGCCCCAGTCGCCTGTTCGCCGACCAGATCGGCCAGTGGATTCCCGCCGGTGTCGAGGTCGGTATCGACGCGGGGCAGGGCGAACTGGACCAGCGCGTGGAGCGGCTGGTACAGACGCCGGACGTGCCTGTGGTCCGGGCCTCCGTGGCCACTGGCGCGGCGGCCTCTCCGGCGCCGGTCGTGATCCGCGCGGATGGCGGCCGGGCTTCTCGCGTGCTGCTGGAGCTGCTTCAGCAGTCCATTCGTACAGACCTCGGCGGCGATGTGACGCGCCTCGGCACCAGGTAGGAGGCACCCATGGCGTGGCCTGACCGCCCCCAGAAGCTCCCGCTCCGCACGGAGCTGGCGTTCGGCGCGGACCCGGCGGGGGATCCGGCCACCTGGACGTGGACCGATGTCAGCGAGCACGTCGAGGACCAGTCGATCACCATCAACCGTGGTCGTGGCGAGGAGGGCGGGGAGACCCGTCCGGCCTCGACTGGGCTCGAGCTGGTCAACAACGGCGGGGACTACACGCCGGGGCACGCGGGCGGGGCTCACTACCCGCACGTGCGGCTCGGCGTGCCCGCGCGGCTCTCGGTGCAGGCCGGTGGGCCGCATCTGCGCCTGCCTGCGAGCGGGGCGCACGCCGTCACCGGCACGACATCCGGCCTGACGGTCACCGACCTCGACATCCGTGCGGAGGTCGCCCTCGACCGCGTCGCCGCTCAGTTTCGAGACGTCACACCCGGCGGACGCCGGCCGTGGCAGACCATCGCCCAGGAGATCACCGGGCGCTCGCGGACCGACGGCACCCTGATGTGGCACCTGGCGGCCGACATGCAGGGCGGCCTGCTCCTCATGTGGACTACCGCGTCCGAGGCCCGCCAGGACCGGAGTTCAACGGACGTCCTCCCCTACGGGTCGGGGCAGCGCTTCGCGGCACGCGCCACCCTCGATGTCAACAACGGCGATGGCGGCCACACCGTCACCTTCTACCACGCCCCCACCATGGATGGCCCGTGGGAGATCCTCGGGCAGCCCATTGTCACTTCGGGCACCACGACGATCCTTCAGACGGATGCGACACCGCTGCGACTGGGGCGGGTGACGACGGAGAACCGTCTCGGCGCCGTCGGCCGCCTCTACCGCGCCGAGCTGCGCAACGGCATCAACGGGACCATCCTGGCCAGCCCGGACCTGCGCACCGTGGCACCCGGCACAACATCGTGGACGGACAGCACGGGCAAGGCATGGACCCTGGCCGAGAACGCAGAGATCACCGACTGGGTGCCGCACGTCACCGGCACCGTGGACGAGTGGGCGCCGCACTGGCCGTGGGGCGACCTGTCCACGCCGGGCTACGACGGGGAAGCCCGCACCGACGTAACCGTCTCCGGCATCCTGCGCCGCCTCGGCACGGGGCAGCCTCCACTCCAGTCCGCGCTGCGGCGCCGACTCCCGGCCGGTAACCCATTCGCGTACTGGCCGCTGGAGGACGAGCCGGGCGCCACGTCAGGGGCGTCCGGCCTGGACAGCGGCAAGCCGCTGAACGTCAGCGGCTTGCGGTTCGGTCAAAGCACGTCGCTGCTGTCGTCGGATGCCCTGCCCACCGTCACCGCCGGGGCCCGCATCCGCGCCAATCTGCGCGCGGGAGCACAGGGCGAATGGGCCGTGACGATGCTCTACAACCTGGCCCAACTACCGCAGAACGACTCCGTATTCTTCGAGGTCCAGGCCGACCGCGGTGTGTGGACCAGCTATCGCATCACCCTGAGAAGCAACTCCGTAGTCTGCGACGCCATCGACGACTCCGGGTCCAGCTCGTCGACCACTCGCCTCTTCAACGTCCTCACCTCGACGTTCTACGGCGGGTGGCGACGCTTCACCCTCCAGGCCACGCAGACCGGCAACACCACCGAGGTCCGCGGGATCTGGCGGTTCCTGGACGGCGACGGCGGCGGGTCGGGGGGTGGTACCTTCACCGGTTCGGCCGGGGTCCTCAGCCGCATCGACACCACGTTCGGCGCGGAGCTGGAGGGCATGGCGATCGGGCACCTGTCCGTCATGCGGCGCGCCGACGTCTGGGTGTACGCAGCTGCGGAGGATGGCTTCGCTGGCGAGACGGCCCTGGCCCGTATGCGGCGCCTGGCTGAAGAGGAGCGTATGCCGCTCAGCGTCATTGGCGTCGAGGCGTCCTCGCCCGCGATGGGCCCCCAGCGCATCGCTACGCTTCTTGACCTCGTCCAGGAGTGCGTGGATGCCGATGGCGGCATCCTCACCGAGCTGCGTGGCCAGCCCGGCCTCCAGTACCGCAGCAGGGAGAGCCTCCTCAATCAGCGGCCCGCCCTCGTCCTCGACGCGCAGGCCAACGAGATCGCCGCGCCGTTCAGCCCGGTCCTCGACGACCAGCGCACCCGCAACCGCATCACCGTCTCCCGCGAGGGCGGCTCGTCGGCGACCGTGGAGGACGCGGAGTCGATCGCCGAGTCCGGCATCTACGACGCCTCGGCGCAGCTCAACGTCGCCTACGACACGCAGCTAGAGGCGCTCGCCGGGTGGCGGCTGCACCTCGGCACCGTCCGAGGCATGCGCTACCCACAGGTCGGCGCCGACCTCGCCATCGCCCCGCGGCTCATCGACGGCTGGCTGTCGGTGGACTCTGGAACCCGCATGGACGTGACCGGCCTCCCGCCACAGCACCCACAGGGCACCGTGCCCCTCATGGTGGAGGGCACCACGGAGACCATCACGCCGACCCGCTGGACGGTCCGCGCGACCTGCTCACCGGCGTCGCCGTGGACGGCCGGGGTTGTGGGCGACGACCAGCTCGGCCGCGTCGACACGGACGGCACCGTGCTGGCCGGTCCTGTCGCGTCCGCCGACGGTGCGATCCTCACGCGGGTCACCGCCGGGCCGACGTGGACGCGGGCCGCCTCCGAGCTGCCCTACGTCCTGAACGCGGACGGCGAGGAGGTGACCGTCATCGCCGTCGCCGACGTCTTCGACACCTTCCAGCGGACCGTGACGGGTGGCTGGGGCACCGCCTCCGGCGGCCTGCCCTGGCTTCTCGGCGGAGGCGCCGCCGCTGAGCGCTCCGTGTCGGCTGGCCGCGGCGTGGTCACGGTGTCCTCGGCCACGATCAGCGCCGTCCGTATCCAGGCGCTCGCCGGGCCGCTCGGTGACGCCGAGGTGCGGGTGCGGATGTCTGTACCGCAGGTGTCCACCGGCGCCGCCCTCATCCCCGGTGTGCTGCTGCGGTACGCCGACGGCTCCAACTACTACCGGGCCCGCCTGCACTTCAACGCTGGCGGCACCCTGTCCACGAGCATCACCCGCACCGTCACGCAGGTCGGCTCCACCGTCACCGTCTCCGGCGGCTACACGGCCGGCGCCGAGTTCGAGGTGCGGGCCCGCGTGGACGGGCACCGCCTCCGCATGCGGGTGTGGCCGGTCGGCGGCACTGAGCCGACGATCTGGCACCAGGACCAGACCATCACCACCGACCCGATCGAGCACGGCCTCGTCGGCGTCACCGCCGGCGGCTTCACCGGGAACACCAACGTGGACCCGCAGATTCGCTTCGACCTGTTCGAGGCTGTCGGCGTCCAGCGGATGACCGTGACCCGGCCCGACCCGCAGGACCACGCGGCGGGCGGCGACGTGCGCCTCGCCCAACCCGCCATCGTCATCTAGGAGGCCGCTGTGCCGTTCCCCTACCCGTGGCAGCCCGGCATGCGGATCACCGCCGAGCGGCTCCGCGCCGGGCTGCTCACCGGCACCGTCAACATCACGCCGACGGAAAACGTCCCAGCGTCTGGGGCTCTCGGCGCCTACCTGCGCGGGACGGCGGCGGTGACCTTCCCAGCCGGGACGTTCACCGAGACGCCCCGCATCTTCCTTACTGGCCGATCCTCGGTCCCGGGCGTGCTCATCGAGTGCAACTACACCGACCAGTCCGAGAGCGGATTCACCATCACCATCGCCCGCCAGACCAGCACCCTCACCGTCGTCGACTGGCTCGCCGTCGCCGCCTGAACGGAGGCACCTTGTGGACACCCTGACCGTCACCGGCCGCTGGCTGTCGACCAACCTGGCCGAGCCGCTGGCGGGCCAGGTCACCCTCACGCCCCGCCCCCGTCGGCTCATCTCCCCGGACGAGGACACCCAGCTCGGCGGGCCCGTCTCCGGAACCCTGGACGAGGAGGGGCGCGTCGCGATCACCATCGTGGCCCCGGGCGGCGGGCTCCTCCCCGAGGAGTGGCTGTGCCAGGTCGACGAGGAGATCGACGGCGCCCGGCGGGCCGTCTACGACGTCATCCTCCCTACCGGGCAGGCCACCGTCGACCTCTCCGACCTTGCGCCTGTCCGCGCTCCGCACGAGTCCTACATTCGCGTCCCCGGACCGCCGGGCCCACCCGGTCCGCCCGGGCCGACCGGACCTGCGGGCGAGCAGGGACCTGCGGGGGCCGACGGCTCCCCAGGCCCGGCCGGAGCGGACGGCCCCCAAGGGCTCGCTGGCGAGCCGGGGCCGGAAGGTCCGCAGGGACCCGAGGGGCCACGCGGCCCGGCCGGTGAACCAGGCGCCGCAGGCGAGCAGGGAGAGCCGGGGCCAGCGGGCGACCCCGGTGAGCAGGGGCCACCCGGACCCCCCGGTGACCCGGGACCGCAAGGAGACCCCGGACCCCAAGGCCCGGCCGGAGAACGTGGACCCGCTGGCGAGCAAGGAGAACCCGGGCCTGCTGGCGAGCGCGGCCCCGAGGGCCTGCAAGGACCCGCCGGGGACTCCGGCCCGGAAGGCGCACAGGGCCCCAAGGGGGACCCGGGCGAACCGGGGCCGCCCGGTGACCCTGGCGCCCCGGGTGCCGATGGTGCGCAGGGCCCCAAGGGTGATCCCGGCGAGCCGGGAGCCGACGGCGCCGAGGGACCGCAGGGCCCGAAGGGCGACCAGGGCGACCCTGGTCCGCAGCCGCCCCTCGGTGCGGCCGGAGCCGGCGCCGACATCGCGCTGCGTTCCACCGACCCGACCACCACCAACGCCCGTACCCCGGTGGCCCACGCGGCCACCCACGCCACCGGCGGCGGCGACCCCCTCACCCCGGCGCAGATCGGCGCCCTCGCGGTCACCGCCCGCGGTACGGCGAACGGCGTGGCCTCGCTCGGCGCCGACGCCCGCCTGCCCGCCGCCCAAGCGCCCGCCGCATCCCCACGGAACGTGTGGACGCCGCAGGCCCTGGGCTTCCAGGCGTGGTCCGTCGACCCGGCGGCCGTCTCCAACCCGACCACCACAAAGGCCGTCGTCGTCGGCCGCACCTACATGTGCGGCATCAACATCACCGAGAGCACGCAGGTCAACCGGGTCGTCATCATGGCCCGCGGCTGGGCCGGAAGCACTGCCGTCCCGGCCGCCCGGTTCTTCGCCGGGATCTACCGGGAGGACGGCACCCGCGCCGCCTGGTCCGGGTCGACCGCCCTGTCGAGCGTCCCGGCGGCCGGGCAGATCACCGGGTCCGCGCCCGGCATGCGCAACAACCACATCGGCGCCGTGCCCATACCGTTGACGGCGACCGCGACCCTGGCCCCCGGCCGGTACTGGGCCGCGTTCCTCATGTCCGCCGGCGCCGCCACGGACATGTACTACATGCACATCCAGAACGAGGCACCGTCCAACCCCGGCAACTTCTTCCTCGGCGCGACCGCGTTCCAGCGGCACTGGTGCATCCCCTCCGGGCAGACCACCCTGCCGTCGACCGTCGACCAGTCCACCGGCGAAGTCGGGCTCGACCCGGCCATCATGGCGCTCGCCCTCGTCTGACACCCCACCACCTCGAGCCCCGCGCCGCATCGGCCGGGGCTCTCCGCATGATCGGAGACCGCGCATGGCACCACCCATGACCCCGGCCACCTTCCTCGCCGCCCTCAAGGCCGAGGGCGTCACCGTCGTGGAGGTGGGGAGCTGGCGCACCCACAACCGCAACAGCAAGGGCGCCTGGGGCCCCCTGAACGGCGTGATGATCCACCACACCGTGACCTCCGGCTCCGCCCGCACCGTGGAGATCTGCCGCAACGGCTACTCGGGCCTGCCCGGGCCGCTGTGCCACGGCGTCATCACCAAGGACGGCCGGGTCCACCTCGTCGGCTACGGCAGGGCCAACCACGCCGGCGCCGGCGACGACGACGTCCTCTCCGCAGTCATCGCCGAGCGCGCCCTGCCCAAGCCGGACGAGGCCAACACCGACGGCAACGCCCGCTTCTACGGCTTCGAGTGCGAGAACCTCGGCGACGGCAAGGACCCCTGGCCCGCCGCCCAGCTCGACGCGATCGAGCGCGTGTCGGCCGCGATCTGCCGCATGCACGGCTGGGACGCCGCCTCCGTCATCGGCCACCTGGAGTGGCAGCCCGGCAAGGTCGACCCCCGCGGCTTCACCATGTCGTCGATGCGCGACCGGATTGAGCGCCGCCTCTCCGCCCCACCCGGCAAGACCCCCACCCCCACCACTCCCGACAAGGAGACGCCCATGTCGTACCGCGACGTGTGGGAGCAGGACGCCGCCCCGGCGCCGGACAGCTCTCCGACGAAGAAGACCAACCCGACCTGGAAGCCCATCTCGTTCCTGCGCGAGATCTACGACCTCGCCCGCGAGACCCGCGACCTGGTCCGCGACATCCGCGACCAGCAGAAGCGGGGGAGTTGATGCCGATTCTCAACCTCACGCCCCACCCAATCCGGCTGTACGCCAACGAGCGTGAGGACGGCACCGACGACCTCGACCCTCACCTGCGGGAGGTCTACGCGCCCGAGCCGACTCCGGCACGACTGGCCACGTTCGAAGTCAGCAGCGGCATGTGGCCCGTGCTGGTCGAGTTCGGGCACGCCCAGAACCTCCCGCCGAAGCGAGACGGGTACCAGTACATCGTCTCCCTCGTCGTCGCGCTCGCCCTCGCCACCCGGCGCGGCGACCTGCTCGTCCCCTACCGCGAGGTCCGCAACGCCTCCGGAACCGTCATCGGCTGCCGCTCCTTCGCGCAGCCCGTCTGAGAGGAACGCCGTCATGGCCGATCACATCTCCCTGCCCGACGCGCAGACGGTCGTGAAGACCGGCGCCGCCTACGCCCGCGACCTCGCCGAGCGCACCGCAGCAACGTTCCTCCAGGCGTTCGTCGGCGGCGTGGTCCTCACCCAACCGTTCGACCTGGCCATGTGGCAGGCCGCCGCCGTCGGCGGGGTCGCCGCCGCGGGCGCCCTGCTGAAGGGCCTCGTCGCCCGCTGGCGGGACGTCACCAACTCGGCGTCCCTGGCGAAGGGCGTCTGACCCGCACGTGAACTACCGATCCAGGAGGCGCTGATGGGTGAGCTGTTCGGCCTGAAGATCGCCGACCTCGGCGCCGTCACGCTCCTCGCGCTGGTCGTCCTCATGGTCCTCACCGGGCGCCTCGTGCCCCGCCGGACCTACGACGACCTGAAGGAGGAGCGGGACACGTGGCGGCAGGCCCACGTCGTCTCGGAGGAGGCGCGGGCGATGGAGCGCGCGCAGACCCGCGAGCTGCTGGAGCTGGGACGCACCGGCGCCCACGCACTCGCGGGTCTGCGCGCGGCCGCCGCCGACTCGGAGGAGGTGGGCACAGGGTGAAGTGGCCATGGCGCCGCCGACACGGCGGCCGAAGTCCTGGGCAAGCAGCAGCCGACCGGGCCCTTCATCGGGCCCGCGCCGACCGGCAGGAGGCCGCCGACCGGCAGCCCGCCGTGCAGGAGACGGCCGAGACCCTGCGCCGGTACCGCGAGGAGAACCACTTCGCGCAGCTGTTCCGCGCGAGCATCGAGGGGAGGCGGGCATGAGCTTCGCCCAGCTGCTCAACACGAGCGTCAGCGCCCTCGTCGCCCTGAGCGCGGCCGTCTTCGTGGTCACCTACCACCGGCTCGCGCCGTGGCGCTCCACCCCCATGGGCTGGCACCTCATGCTCCTCGCCGCGACCCTCGGCCTGCTCGGCCTGTACACCGTCGTCATCACCATCGTCGGCCTCGACGGGACCCCGGCGACCGTGCTCCGCATCGTGCGCGCCGGCCTGCTGCTGCTCGTCGCCGGCCTGCTCGCGCAGCGGACCCTGATGGTGACCCGCGCCCAACGCCCCGAGGGGGACCCTCATGCCCGACCCTGAGCCCCGTCCGGCCGAGCGCCGCATCGACCCGGCCGCCGGAGACACCGCCGCCCTGGCCGCCCTCGGCCTCGCCGACCCGGTGCCCATCCCGTCGGCCGACCCGTTCCGCGAGCCGGTCTACCCCGACGGCCCGTGGCCCGGGCCCGACGACGAGGACTGACAACGCCCCCGCCCCCTGCCGATGCAGGGCGGCGGGGGCGCTTCGTCGTACCCCGCGGCCGCGGGGAGAACCGCTCGAGACGTTGTAGCCGAAGACCAACGGCGGGCCACCCCGCAGTAGCAGGAGAGTCGGCTGCCCACCTAGGAGCTGGACACGGATGGCGGACCACCCCCGCGCTCGTGCGGGGACGACAACGTGTTGCCGTTGATCGTCACGTCCTCGTAGGGAGCACCCCCGCTCGCGCGGGGACGACGCCGAGTCGCTCGCCGACGGCGCCGAGAAGGTCGGACCACCCCCGCTCGCGCGGGGACGACATCAGCAGGGCTCGGATGAACACCTGGATGCGGGGACCACCCCGCTCGCGCGGGGACGACATGGTGCGGGGCGCCTCGCGGGAGCTGGACCGGGGACCACCCCCGCTCGCGCGGGGACGACGCTTCCTGACCTGGGACGCTACAGGGCGGGGCGCCGGTTCTCAGTCGCTTCCGGATTCCGGGTGCCGCACGGCCTCCCGCACGGCCTTCTCCACCTTGTACCGGTTCTTGTTCTCGGCGACGGCCCACTCGGTGATGGCGGCCTGGGCCCGGGCGCCCGCCTCGAACCAGACGCGCCGCTGCCGCTCCCGCTCGTCGTTGTCGGTGAGCTCGGCGAGGCGCGCCCACTCGGCGTCGGCGGCGCGCTGGAGGTCGATCAGGCTGTCGGGGATGTCCACGGCCGGATCCTACGCCGCAGGTCGGACGGCATCGCGGACCGCCTCTGCCCACTCCGCGATCAGCTCCACGTACCGGGCCCGGTCGCCGGCAGCCAAGCGGCCGCCCGAGCGCAGCATCAGCGCGCGGATCTCCGCGTTCACCTTGGCGGCAGGGCGCGGCCGGGCTGCGGGCAGGGAGGACATGAGGGCAGGCTAGCGCCCCGCGCCGACAGCGCGCTCGACCTCGTCGAAAGCGACGCGCCACGGGAACTCGCGGCCTTCGCCGGGCGGATTCGGCTGGAACCCGCCCTCTCCGTACAGCACGCTCACGCCCATGTCGCGCAGCTCGGCAACGCTCCGGTCGAGCGCTCGGTGCTGCGCGTAGGCGGCGTTCACGCACGGCATGGTCACCAGGGGGATGCCCTTGCCGATGCCCTCGGCGCACACCCCGACGACGAAGGAGCTGGTGATGCCGAGGGCCCACGCGTTGATGCTGTTGAAGGTGGCGGGGGCGAACAGCACGACGTCTGCCTTCGGCCAGGCGTCGGCGGTCCCGGGCGCCTTGTACTCGGACCGGACCGGGTGCCCGGTCAGCCGCTCCAGCTCGGCCGTCTGCGGCTCCAGCCAGCGGGCTGCCGTCGGGGTGAGGCCGAGGCACACGTCGAAGCCACGCTGCTGCGCGTCCTCGATCACCGTCCCCACGCCGAGGACCGGAGGGGCAGCCGAGCCGAAGAGGTACAGAGTCGTCATCGCCACATCCCACCCCGCCGACCACGGCAGACGCAACCGCCCCCGATCGGGGACGACCGGGGGCGGTTGGGGTCCCGTCGCCGGGCGGCGCGGGTATGTTCCAGATGACGAGTCAGGAACAGGGGGACCAGTATGCCCACACCGGACGACGACAGCACAGGTGGCCGCATCCGTCGGGAGCGGCGCCGGGCACGACTCAGCCAACGCCAGCTCGCGGATCGCATCCCGTTCTCCTACAGCCTCCTGAATCAGGTGGAGTGCGGGGCGCGCGCAGCGTCGACGGAGCTGGTCGCGGCGGTCGCCGCAGCCCTGCGCATCGACGTCTCCCTGCTCACAGGATCTGCCGTGACCGATCAACTTCCCGGCCAGCGGGCCGACATCGTGCGCCCGATCCGTGAGGCCCTCGACCTCTACGACCTTGCGCCGGACGTGGAGCGCCCAACCCGCCCGGTGGCGGCCATGGTGGAGGCCGCCGACCGCGTGTGTCAGCAGGTGCGGGCGACCCACCTGCGCACCGCTGCGAGCGCGCTGCCGGACCTCATCGCCGACTTGACCCACGTGGCGCTGACTTCTCCGTCCACGGAAGGGTGGCGGGCGCTCGCTTCCACGTACCGGTCCGCGCACGACGTGGCCCTGAAGCTGGAGCACCGGGACCTCGCCGCTCTCGCGCTGGAGAGGATGGGGTGGGCCGCCGAGCGAGCCTCCGACCCGTGTCTTGCGGCGATCCGCCAGTACAAGCGGGCCCTGTCCTGGCAGGACTCCGAGCTGGGGCTGCGCCTCGTCCAGGCGGGCCACGACACGCTGGACGGGCAGTCGTCCCGCGAGGCGTTGGCTGTCGCCGGGCAGCTGCACCTCGGGGCGTCGGCGGTTGCCGCGCGGGCCCGGGACCGGGCGGGTGTCGCCCGGCACATCGAGGCGGCCCGCGAACTGGCCGCCCGCACTGGCCCGGCCCAGTCGATCCACTGGCTGGGGTTCGGCGCGCTCAACGTCCGCCTTCACGCGATGGGTGCCGCGATCACCATGCGCCAGTACGACGATGCGCTCCAGCAGGCCAGGGCTCTGCGCATCCCGCCGTCGGCGATGACATCGCGCCGGGCCCGCTTCCTTGTCGACCGGGCCATGGCCGAGATGGAGACCGGCCTCGGCGACACGTCGCTGAGGCATCTGGTTGAGGCGCGGGCGGTCGCCCCGGAGCAGACCCGCTACCTGCCTCGAACGCGGGAGACGGTGCGCGGCCTGCTGCACACCACCCGCCGGCCGTCGGAGCGGCTGACGCGCATGGCCGCCTGGGTGGGGGTGTGACGCTCACAGATCTGTGAGCGTTCCGGCCTTGGCCGCGCGCCATCCTGCTGATCTCGATCGGACAGCAGGGGATGACCATGGCGACGACAGTGCAGGAGTTACCGCAGCCGACCGCTCTCGGCGAGCGGCAGCTACGGGGCACCGAGTGCGTGTGGTGTGCCGGACGCCTCGACACCGCGACGGCCGTGGACCTCGGCGTGCGCCCGGACCCGCAGTGCCCGTGGGCCAGCTGGTTCCCGCGCGCCTGCCCCGCCTGCGCGGCGGGCCGGTCGTGAGCGGCCTGTGCGCGCCGTGCGGCATCGGCGAGCACGGCGCCTGTGCAGGGAACTACGACGTGTACATCGGCGGCTTCGGTGCGCCAGCGGTCCGGGGTCGCTGCGCCTGCCCCTGCTGCTCGCAGGAGGTGCGCGGCCTTTGCGACCGGTGCGGCAGCCCGTGCAGCCCGGAGACCGCCGCCGACCATCGCACCTGCCCGCTCCGCCTCGACCCCACCCTCGACGCCCCGACGGAGGCCACCCGATGATCTGCGCGCGCTGCGACAAGGCGATCCGCCCCGGGGAGAAGTACGACCGGACCCCGATCCACGGCAACTCCGGCGCCCAGTTCGACGTGCTCCGCCACCTCGACTGCCCCAGTCGGCGGAGACGGGCCCGCCGCTGAGCTGACCCCGGCCGGACGCCGACCCGGCCGGGGTCAGCCGCCGACCAGCTTGGCGAGCGGGGTGTCGAGGGCGCAGGCGATGCGCGCGAGGTCGCTGTACCGCGGGTCGTTGGTGCCGCGCTCGATCCGCTGGACGGTGTCGCGGGAGACGCCGGCCGCCTCCGCGAGCTTCTCCTGCGTCAGGTTCTGCCGCATCCGCCGCTCGCGTATGCGGTCGCCGAGGGCGCGGCGCTCTGCGTGGAGCCAGGCGGGGTGATCTTGGGGCGGCACTCGACAAACGCTCTGCGCTGCATAAGCTGCTGTCAGCAGCTAGGTAGCTGCATTCTTTGATCTTGTGCGGCGCAGAGGTCCGTCGTCGAGATCGAGAGGCAGGGGGGGCAGGTGCTACGGGAGATCCCGGTCCGGGCTGGTCGCCCACCACGCCATCACCTGATACAGCGTCCGCATGCCCAGCGCGGAGCGGAGCGCGGACAGCTCCTTCGTGATGGTGCGTTCGCCGAGGCCGAGCCGCCGCGCCGCCTGCTGCGTGGTGTACCCCGCCTCCAGCTCCACCAGAATCTGCCGCTGGCGTCCCGTCGTGGCACCGCCCACAGGGACGGACGACCAGCGCGCCGCGCGGTTCCACAGGGCGTCGAAAACATGCACGGCCCAGGCGACAGACCCACGGTCGGTGACGTGCCAGCCGCTGTCGGCCTCGGCCCCGGAGACGACGTGGTTGTCGATGAACAGGTGCCGGGAGTCGAAGATCATCATGCGGGGGAAGCTGCCCGACATCGTCCGGGCTGCCGAGCCCGCGTCCACCATGGCGTCGATGGAGGCTGCCGTCTGCGGGTGGGCGGCCGCCAGGCTGTTGTACAGCCCTCGCACCTCGGTACCGGCGTGGAGCACATCGATCGTGCGCTGCACGCCGAGGGCGACGATCTGCGGGTCGCGGTCGGCCGGCTCGCCCGGCTGGGCCGTCATGATGGAGATCGACGTGGAGGCGGCGACCTGGCCGATGCGGTCGTTCATCGCGGCGCGCGAGGCGAGGAACTCCGACGCGGGCCCGCCGTACATGCGGTGCGGGTCGTAGTCGCTGGCCAGGGCGTCGAGCGCAGGCACTCGCCTTATGCGGGTGACGAGTTCCGCCAGCTCTTCCAGGGCCTCGCCCATGAGTCCGCGGGCGGTAGCTCGCGGGTCGTGCGCCACCCAGGTTTCCTCGTGCGGGCGCCACTCGATCAGGCCCAGTTCGGCGAGTTGCTCGGTGGCCGGGCCTGCCTCCGGCGGGTTGCCGATGGCAATGGCTCGGTAGGCGGCGATCTGCTCAGGGCTCAAATCTCTACTCAACATCCGTACAACCCCCGGGAGTTGGCGATGCGGGAACCCGCACATGCCGATTCTGGCACGCCGCGCCTCTTGGTTCACCCCTCAACCACATGCAACGATTCCTTCACCGCGTGTTACTCGGGCACGTGTTCGAGTCATAGTCCCGTGGAGGATGAGCATGAAGCTCCGGATCGCCCTCGCCGCAGCCGCCCTCGCGGCCGCCGCCGCCGTCACCCCGCTCGCCACCGCCAGCGCCGACCCGGCGCCCGCCCCGCCAGCCGCCGCCGACGACATCGGCTGGGGCGCCCCGGGCAAGAACCCCACGCCCTCCCCGTCCCCCACCGCCACACCCGCCGGAGACATCGGCTGGGGCTGACACGCACAAGGCACTGCTGAAGAACGGGGAAGAGGCATGGACGTACATCTCGTAGAGGCCCGGCTGCCCGGCGGCGTCCTCGCGTGGGCGGATCGACGGCGAACGCAGGCGGTGATGTACGTCCACCCGGACCTGGCGTCCGGTGGTGCGCTGAGCGCCGCCGGACGCCACCTGGTCCGGGAGTCGCTCGACGCCTCGGTCGGCGTCGGCTGGCGACTAGGTGGGGGAGTCCCGGACTTCGCCCTTCCGGGCCCGCCCCTCTCCTGGGGGAAGTGAGCCGCCCGCTTGGGAGAATCCTGGGAGATGAATCTCCCGGAGGCATCCTGGGGAACGCGGTGTAGCGCGGAGTAAGGCAGACGCCTGCTGGGCGTTCACCAGCGAAAGCGTCTCAACGCGCAGATCGGGAATGACTCTGCCGCCATCTACACCATCTTCGAGGGCACGAGCGAGATCCAGCGCCTGGTCATCGCGCGCACCCTGGCGGGTATGCCGATCCGCTGACGCCGACGCGACGGTGCGCGACCGCCGCCCTCCCTGGCAAGGGGAGGGCGGCGGTCGCCGTATGCGGACAAGCGTGACGAGCCGGGACGAATTAGCCTGTTGCCCGGCATGAGCCGCCCGTCCGCAGCGCAGGGAGCACCCCATGAAGGCAGCCGTGGTCCGCAGCTTCACCGAGCCGCTCGTGGTCGAGGAGCGGGAGGTGCCGGAACCCGCCGGGCACCAGGTGCTGGTCCGGATGGAGACCTCGGGCCTCTGCCACACGGACATCCACGCCGCCCACGGCGACTGGCCGATCAAGCCCAGCCCGCCGTTCGTCCCCGGCCACGAGGGCATCGGCGTCGTCGAGGCCAGAGGCGACCAGGTGGACCACGTACAGGTCGGCCAGCGGGTCGCCATCCCCTGGCTGGGCGAGGCGTGCGGGCACTGCGAGTACTGCGTCAGCGGCTGGGAGACGCTCTGCCTCCAGCAGCAGAACAGCGGCTACTCCGTCGACGGCAGCCACACCGAGTACGCCCTGGCCCACGGCACCTACGTCGTCCCCGTGCCCGACGGCATCGACCCGCTCGACGCCGCCCCGCTGACCTGCGCCGGCGTCACCACGTACAAGGCGGTCAAGCTCTCGGGCGCCCGTCCCGGCAAGCGCGCCCTGGTCTCCGGCATCGGCGGGCTCGGCCACCTCGCCCTCCAGTACGCCACCATCTTCGGCGCCGAGACCATCGCCGTGGACATCACCGACGAGAAGCTCCAGCTCGCCCGCGACCTCGGCGCCGACCACGTCGTCGACGCCCGCACCCAGGACGTGGCCGAGGAGGTGCGGCGGCTCGGCGGCGCGGACGCGGCCATCTCGCTGGCCGTCAGCAACGACTCGTTCCGCGCCGCCTACGACTCGCTCAACCGGGGCGGCACCCTCGTCCTGGTGGCCCTGCCGCCCGAGGGCGAGCTGTCGATCCCGGTCTTCGACACCGTGCTCAACGGCACCACCGTCACCGGGTCCATCGTCGGGACCCGCGAGGACCTGGTGGAGGTCTTCCGGCTCCACCAGCTCGGCCGTACCCGCGTCGTCCGCGAGACCCGCCGCCTGGAGGACATCAACACCTCCATCGACGAGGTGCTGGACGGCAAGGTGACCGCCCGCCTCGTCTTCGACCTGCGCTGACCGGGGCGGGCGGGACGGGGTCAGCGGTACTCCAGCTCCGTCAGCTCGTCCCCGCCGGAGAGATGGCCGGTCACGCGGGGGTCGGGCTCACCGTCGGTACGGACGGCCGCCGTCCGGCCCCGCTCCCGCTCGTGCCCGGAGACCGTCAGCGCCCGCACCTCGCGGCTCCCCGCCGCCAGCGAGTACCACCGGCCCGACGGCGCCCGCCAGGCGGTGCTGGCCACCAGGTGCTGCCCGAACCGGCTGCACGCCGCGGTCGGCCCGGTCTCGCCGACCAGCCGCACCGCCGCCCGCCCGGCCTCGGGACGCAGATGGACCAGGACGTGCCCCGGCCCCTGCCAGGTGCTGACCCGGGTGCAGCCCCACACCGCGCGCCCGGCCTCCTCCGGCAGCGTCTGTTCGGCGAAGTCCCAGGTGTTCACCGACCGCACGCCGCTCCGCTCCAGCCCGGCCAGCCGGCAGCCGACCCGGGCCCACGCCGCCAGCGCCGTCTCGCCGGTCGCCTCGCGGGGCGCGCGGGCCCCGGCCCCCGAACCGGGCAGCGGCGTGTACGAGAGGTGGGCCGCCGTCAGTTCGCCCAGGTCGGTCACGAGGAAGGCGTGGTCCTCCACGACCCGGGGCGAGGAGCGCAGCCGTACCACCGGCCACCGCTCACAGGCCGCCCCCGCCACCGGCGGCCCGGCCACCGCCTCCGTCACCCCGTCCTCGTCGACCCGCAGCTTCCGGGCATCGCCGCCGGGCCGCAGGAGATCCCGGGTCTTGGCCTCGCCCACCCAGGGGGCGAGCAGGAACCGCACGCCGCTCTCGGTACGGCTGACCACCAGCGCCGCCGCCGTCGTCACATCGGCCTCGTCGGTCCTGGCCACCTCCAGCGAGGGCGGGGAGGAACCATTCAGCGGCTCGGCGTAGCGGGCCGCGCGGGAACCGTCGTGCAGCAGGACCACCGCCGCCCCCGCCACGTCGCCCGCGTAGAGCAGCCGGGGCGGTCCCGCCGGGGGCACCGCGGGCGTCGTACGGGAACGGGACAGCTTCACCCCGGCCGCCTCCGGCGAACTCCAGGCGCGCAGCGCCCGGCCCAGCAGCTCGGTGTCCTCGGTACGGCCGCCGCGCGGCGGCCACGCCGTGAAGTCCACCCGCGCGGTGTCGGCCCACTGCGCGGCGTCGGTACGCCGCAGCAACGCCGGGTTGAGCGCCGGGGTCCCGCCCCGCGCCTCGGCGACCGGGGCCACCCCGCCCTTGCCGTCCGCCTCGCTCACCTCCGGGCCGGGCGCGGGCGCCGGTCCGGAGACCGCCAGCGCGCAGGAGGCGGCCACCGCGACGAGGCCCACGCCCACCAGCCGGCCCTTGCGGCGGCGGCTCAGCAGGTCGGTCGGCCGGGTCTGCACCTGGCAGGGGTCGAACTCCTGGGAGGCGAGCAGTACTCCGGCCGCCTCGCCGGTCCGCGCCCGTACCCCGGCCGCCTCCTTCAGCGCCGCCTCGGGGTCGGCGACCCCGGCCGCCGCCAGCAGCGCGGCCACGTCCTCCGTACCCAGCTCCTCCAGGGCGTCCAGCGCGAAGGCGGCCCTGGCGGGTGCCGAGACCTCCGCCAGCACCCGGTCGAGCGCCAGTTCCTCGGTACCGCCGGCCCGGGGGAAGAACCGCAGCCCCCACACGGCGGGCAGCCCCGGGCGCAGGGCGCGCGGCGGCGGCAGGCGGCGCGGCCAGAGCCGGGGGCGGTGCTCGAAGGCGAGCGCGGCCGACAGGACCTGGCCGCGCACCCAGGCGTAGCCGACCGGGTCCGTGCTGCCGTCCGGGACCGGGACCTGGCCGCGGCCCGTGGTCAGGCCGGGCAGCGCGCGCTGCACCACGCCGTGGGCCAGCAGGACCCGCCGGTGGCGGCCCAGCGCGGGCGGCAGCACCAGATGGGCCAGGCGCACCAGGCGCGCGTAACGCTCGACCACCACCGCCTCGGCCCGGTCGAGCCCGATCCGGGCGGGGGGTGCGGCGTCGGGACGGTGGGGGAGGGGCGCCATGGGTCGGAGAGCCTTTCGCGGGAGCAGGAGACTGGTGCTGACGAGCACTCCGTCAAACGAGTGAACCGGAGGAGGGTCACAGCGCCCGCGCGCACCCGCTCCCACCTGCGCGGCGGCCCCGCGCGCCCACGGCCGCCCCGCCATCTGTGATCCTGGAGCCAGCGAGGTGCGCACGGCGGACGGGAACCCGCCGCGCCGCGCCACCGGACGGCGCCACCGCGCCGCACGACGAAGAGGAGAGGCACCAGAGATGGCACAGCACGTGCGGGGCGTCATCGCCCGCGCCAAGGGCGAGCCCGTGGAACTGACGACGATCGTGGTGCCGGACCCCGGGCCCGGCGAGGCCGTCGTCGACATCCAGGCGTGCGGCGTCTGCCACACCGATCTGCACTACCGCGAGGGCGGCATCAACGACGACTTCCCCTTCCTCCTCGGCCACGAGGCGGCGGGCGTGGTGGAGTCGGTCGGCGAGGGCGTCACCGAGGTCGCCCCCGGCGACTACGTGATCCTCAACTGGCGTGCCGTCTGCGGCCAGTGCCGGGCCTGTAAGCGGGGCCGCCCGCAGTACTGCTTCGACACCCACAACGCCAAGCAGAAGATGACCCTGCTCGACGGCACCGAGCTGACCCCGGCGCTGGGCATCGGCGCCTTCGCCGACAAGACCCTGGTCGCCGCCGGGCAGTGCACCAAGGTCGACCCGGCCGCCTCCCCGGCCGCCGCCGGGCTGCTGGGCTGCGGCGTGATGGCCGGCATCGGCGCCGCCATCAACACCGGCAACGTCGGCCGCGGCGACTCGGTCGCCGTCATCGGCTGCGGAGGGGTCGGCGACGCGGCCGTCGCGGGCGCCCGGCTCGCCGGGGCCCGCCGGATCATCGCCGTCGACATCGACGACCGGAAGCTGGAGAAGGCCCGCTCGGTCGGCGCCACCCACACCGTCAACTCCCGCGAGGCCGACCCCGTCGAGGCCATCCGCGAACTCACCGACGGCTTCGGTGCCGACGTGGTCATCGAGGCCGTCGGCCGGCCCGAGACCTACCGGCAGGCGTTCTACGCCCGCGACCTGGCCGGCACCGTCGTCCTGGTCGGCGTCCCCACCCCCGAGATGAACATCGAGCTGCCCCTCCTCGACGTCTTCGGCCGCGGCGGCGCCCTCAAGTCCTCCTGGTACGGGGACTGCCTGCCCTCCCGGGACTTCCCGATGCTGATCGACCTCTACCTCCAGGGGCGGCTCGACCTCGACGCGTTCGTCACCGAGACCGTCGGCCTGGACGACGTCGAGGAGGCGTTCGCCCGGATGCACGGCGGCGACGTGCTGCGCTCGGTGGTGGTCCTCTGATGGCCGCTCGCATCGAACACCTCGTCACCAGCGGCACCTTCTCGCTGGACGGCGGCACCTGGGACGTCGACAACAACGTGTGGATCGTCGGCGACGACACCGAGGTGATCGTGATCGACGCCGCGCACGACGCGGCCGCCATCGCGGCCGCCGTCGGCGAGCGGAAGCTCGTGGCGATCGTCTCCACCCACGCCCACGACGACCACATCGACGCCGCCCCCGCCCTCGCCGACCGGTACGGCGCGCCGATCCTGCTCCACCCGGACGACCTCGTCCTGTGGGACCAGATCCACCCGGCCCGCCGCCCCGACGCCGACCTCGCCGACGGCCGGCAGATCACCGTCGCCGGGACCACCCTGACGGTGCTGCACACGCCCGGCCACAGTCCCGGGGCCGTCAGCCTGTACGCCCCGGAGCTGCACACCGTCTTCAGCGGCGACACGCTCTTCCAGGGCGGACCCGGCGCGACCGGACGCTCCTTCAGCGACTTCCCCACCATCGTCGCCTCGATCCGGGACCGCCTCCTCACCCTCCCCGAGGCGACCGTGGTCCGCACCGGCCACGGCGACACCACCACCGTCGGCGAGGAGGCCCCGCACCTCGACGAGTGGATCGCCCGCGGCCACTGACCCTGCGTCAGGCCGCGCGCCAGACACGGGACATGCGCCCGCTCCCGCCCGGGGGCGGGCGCTTCCCGTGGTACGAGACGGCGCGCCGGGGCCCGTACACACCCCTTACGCACCCCAGGCACCTGGAGATCACCCCCGCACGCCCCCGATAGGGCACCCTGTCCCCGTGTCCTTCGCCTCGACCCCGTCCTCCTCGCTGCCGAGCCAGTCCCCGCCCGCCGCCCCGCACATGGTGGTCTGCGGGGACGACGCGCTGGCCCAGCGGCTCGCCGCCGAACTCGCCGACGTCTACCGGGTCCGCGTGGTCCTGCTCACCCCGGCCGGCTCCGAGAGCCGCAGCCCCGGCCTGCCCGGCGCCGCCCGTCCACCGGGCCGCGCCTCCCTGCTGCTGGGCCGCGTCTCCTCCGTGATGAACCGCAACGGCGGCCCGGCCACGGCCAACGGCCCCACCCCGCCGCCCGCGCCGCAGGAGCCCCGGCGCTCGGGCCAGGTCCGCGTGGTGGACGCCCCGGCCCCCGACGACGAGGCGTTCGCCGTGGCCCGGGTCCACACCGCCGAGGCGCTGGCCCTCGTCTACGACGACGACGAGACCAACATCCACGCCGCCCTGCGCGCCCGCCGCCTCAACCCCCGCCTGCGGCTGGTGATCCGGCTCTACAACCGCAAGCTCGGCCAGCACCTCGAAGAACTCCTCGAACAGGCCGCCCACCTCGCGGGGCTGGAGGACGTCGACGCCGGTGTCACCGTCATGTCCGACGCCGACACCGCCGCGCCCGCCCTCGCCGCGGCCGCCGTCGCCGGGTCGAGCAAGGTGGTCGAGGCCGACGGCATCCTGCTGCGCGCCGCCGAACGCGACCCCTCCCTGCCGCGCCGCCCGGGCGACCCGCCCCCGGTCACCCTCGCCCTGCTCTCCGCCACCGTCAGCGACCCGGCCGGCTCCGAGGGCTCCGACAGCGACGGCGACACCCCCACCCTGCTCCCCGACGACACCGACGTGGCCGACTCCCAGAGCAGCCGGGCCACCGTCGTCCTGGAACGCGTCGGCACCAGCGTGCCGCAGCTCCCGCGCCGCCGGCTGCGTCGCCGGCTGCGCGGCCGGGGCGCCCCGCTCGGCTCGCTCTTCTCCCGGCAGCTGCGCTGGTCGGTGGCGGGGCTGGTGGCCGCCGTCTGCGTCCTGGCGGTGGTCGCGATCGTCACCACCGACGAACGCCCGCTGCACGCCATGCACATGACGCTGCTGGACCTGCTGGCGATCAACGAGCCCGCCGTGGAGGACGGCGAGGTCCTCACCCGGAAGATCCTCCAGCTGCTCGCCTCCGTCGTCGGCATGCTGCTCCTGCCGTTCCTGCTCGCCGCCGTCCTGGAGGCGCTCGGCACCTTCCGCACCGCCACCCACCTGCGCCGGCCGCCGCGCGGGCTCAGCGGCCATGTGGTCCTGCTGGGCCTGGGAAAGGTCGGCAGCCGGGTGCTGAGCAGGCTGCACGAGATGGAGGTGCCGGTGGTCTGCGTGGAGGAGGACCCCGAGGCCCGGGGCATCGCCCTGGCGCGGCGGCTGCGGGTGCCGACCGTCATCGGCGACGTCACCGAGGAAGGCGTCCTGGAGGCGGCCAAGGTCCACCGGGCCCGCGCGCTGCTCGCCCTCACCAGCGTCGACTCGACCAACCTGGAGGCGGTGCTCTACGCCCGGGGCGTCAAACAGGACCTGCGGGTGGTGATGCGCCTCTTCGACGACGCCTTCGCCACCGCCGTCTACCGCACCCTGCGCGCCGCCCACCCGCAGGCCCGCACCCGCAGCCGCAGCGTCTCCACCCTCTCGGCACCGGCCTTCGCGGTCGCCATGATGGGCCGCCAGATCCTCGGCGCGGTCCCCGTCGAGCGGCGGGTCCTGGTCTTCGCCGCGCTCGACGTCGCCGGCCACCCCGAGTTCGAGGACCGCACCGTCGAGGAGGCGTTCCGGCCCGGCTCCTGGCGCGTCGTCGCCCTCGACGCCGCCCGGCCGGACGAACGCCGCGACCACCTCGGCGCCGTCCCGGGGGAGCGGCGCCCGCCCACCCTGGCCTGGGACATCCACCCCGGTTACGTCCTGCGGGCCCAGGACCGGGTGGTCCTGGTCGCCACCCGGCAGGGCCTCGGTGAACTGCTGGGCCGGCAGGGCATGACCGACCCGGCCGGCCGCTTCTGACCCGCGAGGGTCCGCCGGACGGGCCCGAGCGCCGCCCGGCCCATAGCGGGACGGGCGGCGAGGCGCTCAGAGGCCCGCGGCGGCGTCCCGCAGCGCCTGGATGTCGAGCTTCTTCATCTCCAGCATGGCGCGGGTGGCGCGGGTGGCGGCCTCCCGGTCCGAGGAGGCCAGCAGCTCGACCAGGGCCCGGGGCACGATCTGCCAGGACAGCCCGTACTTGTCCTTGAGCCAGCCGCACTGGACCTCCTCGCCGCCGTCGGCGGTCAGCGCCGCCCAGTAGCGGTCGACCTCCTCCTGCGTCTCGCAGTCCACCGAGAGCGAGATCGCCTCGGTGAAGGTGAACTCCGGTCCGCCGTTGATGGCGACGAACTCCTGTCCCGCCAGCTGGAAGGTGACGGTGACGACGGAGCCCGGCTCACCGGGGCCCGCGTCGGTGAACCGCTCGACGCCGAGGATCCGGGCGTCCTCGAAGAGCGAGGTGTAGAAGGCCGCCGCCTCCTCGGCCTGGCCGTCGAACCAGAGATTGGTGGTGATCTTCTGCATGGCGTGCTCCCGTGCGTTCGGCTCCTCCCGGCCACCGGCGCGGGAGGCGGGGCCGCGGCGGCCCCCTCACAGGGATAGACCGCGCGGGCCCCGCCGATTCATCGGGGCAGCCGTTCGGCGGGTACCGGCGGCTGTGCGGTGGTGGTGTGGTGCAGGAGGTGGTTGAGGGGGAGGGTGGCGGCGCCCTGGGTGATGGCGTCGGGGCCGAGCGTGGAGAGCGTGATCTCGGTGTGGCGCCCCGGGTGGTGCAGGGCGTACCCGCGGGTCCGCTCGCGGATGGTGTCCAGCACCAGCGGCCCGAGCTGGAGCCCGGCCCAGCCGCCGATCAGGATGCGCTGCGGCTGGAAGAGGTTGACCAGGTCGGCGAGGCCGGCGGCCAGGTACTCGGCGGTGTCGTCCAGGATCGCCAGCGCCGTCGGGTCCGCCTCGGCGCCCGCCGCCTCCGGCCGCGCGGCCGCGAGCAGCCGGCTGATCCCGTACTCCTCCGTGGCCTCGTCGGGATCGGGGCCGCCCGCCTCGTGCCAGCGGCTCAGGATGGCCTGCGCCCCGGTGTACGCCTCCAGGCAGCCGCGTGAGCCGCAGCGGCAGATGCGGCCCCGCACCTGCACGGTCAGATGGCCGAACTCGGCCGGGGTGCCGTGGTCGATGCCGTGGATCTGCCCGTCGGTGACGATGCAGGCACCGACGCCGGAGCCGAAGAGCACGATGGCCGCGTCGGTGGTGCCGCGCCCGCCGCCGTACCACATCTCGGCCTGGCCCAGCGCCATGGTGCCGTTGCTGATGTGGAAGGCGGTGGCGGGCGGCAGGTCGGTGGCGCCGCGCAGCAGCCGCTCCAGCGGGACGGCGTCCCAGCCGACGGTCTGGCCGTGCACCACCGCCCCCTCCGGGGTGCGCTCGACGATGCCGGGCACCCCGACGCCGATGCCGGTGAGCGCCTCGGCGGCGATGCCCGACTCCTCCAGCACGGCGGCGATGGAGCGCGCGGTGTGCGCGATGACGGTGTCGATGTCGCGGGCGCCGCCGGTCAGCGGCAGTTCGCAGCGGGCGAGTTCGGTCATGGCGAGGTCGAAGAGCTCGGCCCGGACCCGGGTCTCCCCGATGTCGATGCCGATCAGGTACCCGGCTCTGGGAGCCACCCGCAGCAGGGTGCGGGGGCGGCCGCCGTCGGACTCGACGTGCCCGGCCTCCTCGACCAGTCCCTCCGCTGCCAGCTCGGTGACGACGTTGCTGATCGACCCCGAGCTGAGGCCGGTCGCGGGCCCCAGCGCCTGGCGGCTCATCGGGCCCTGGAAATACAACCGTTGCAATACGGCGGCGCGATTGCCGCGCCGCAGGTCGCGGACGGTCCGTCTGTGGTTCTCGGCCATGTGGCTCCTTCCCAGGCCGCAACATACCCGTGTGCGACCTCTTGACGCGACCTTCTCTCGGGGTTTAACTCACGTCCTAAATTAAGCCGTGACGGTGTTCGGGGACTGAACGCCGACGGTCTGGCCGCCACCTGTTGGTGTTTTCCCTGGAAGGGGCGTTTGCCTCATGCGCAGATTCAGAGCCGCCTGTATGACCGCCACAGTCACCGCGCTGGCCACGGTGGTCGCCGGTTGCGGCGGAGGGACCAGCACCTCCGGCGACGGCGGCGCGGACAAGCCCAAGGAGCTCGTCTACTGGGCCTCCAACCAGGGCCCCAGCATCGAGGCGGACAAGAAGATCCTCACCCCCCGGCTGAAGAAGTTCGAGCAGGAGACCGGGATCAAGGTGAAGCTGGAGGTCGTCCCCTGGTCCGACCTGCTCAACCGCATCCTCGCCGCCACCACCTCCGGCCAGGGCCCCGACGTCCTCAACATCGGCAACACCTGGTCCTCCTCGCTCCAGGCCACCGGCGCGCTGCTGCCCTGGGACGACAAGAACTTCGACAAGATCGGCGGCCGCGACCGCTTCGTCGACTCCGCCGTCGGCTCCACCGGCGCCGAGGGCCAGGACCCGGCCGCCGTCCCGCTCTACTCCCTCGCCTACGCCCTGTACTACAACAAGGCGATGTTCGAGGAGGCCGGCATCGACAAGCCCCCGGCCACCTGGGACGAGATGGTCACCGTCGGCAAGAAGCTGTCCAAGGACGGCAAGTGGGCGCTGGGGGCGGAGGGTTCCAACCTCTCCAACAACATCCACCAGGTGTTCGTGCTGGGCCAGCAGCACGGCGCCGACTTCTTCGACGCCGAGGGCAAGCCCGACTTCACCTCGGACGGTGCCGTCGCGGCCGTGAAGCAGTACGTCGACTTCATGGCCAAGGACAAGATCACCGCGCCCGGCAACGCCGAGTACGCCCAGAACCAGTCCCTCCAGGACTTCGCCAAGGGCAAGACCGCGATGGTGCTCTGGCAGGCCGCGGCCAGCACCTTCAAGAGCCACGGCATGGCCGAGGACGACTTCGGCGTCGCCCCCGTCCCGGTCGCCTCCGGCACCCCGGGCACCGGAGAGCAGGTCAACTCCATGGTGGCCGGCATCAACATCGCCGTCTTCAAGAACTCCAAGAACCTCGACGGCGCCACCAAGTTCGTCGAGTTCATGACGAGCGACACCGAGCAGGTCCACCTCAACAAGACCTACGGCTCCATACCCCCGGTCAAGGCCGCCCAGCAGGACAAGGCGTTCGACCGCCCCGACACCGCCGTGCTGCGCGACACCCTCCTGGAGAGCGCCGCGCCGCTCCCGCAGGTCCCCAACGAGTCGCAGTTCGAGACCGCCGTGGGCACCGCCGTCAAGGAGCTCTTCGCCGACGCCGCCGCCGGCCGCGCCATCACCGACGAAGCGGTGAAGACGCGCCTGGCCAAGGCCGAGCAGCAGATGCCGAAGCAGTGAGCGAATCCGTGACTGCCACCGCCGCCCGCCGCCCGGCCGCCTCCGGCCCGGGCGCGGCCGGCGCCGGCCGGCCCTCCCCGGGCCCGGCCGGCGCCCGGCGGCGCCCGCGTATCCCCGCCCGCCTGCGCAAGATCGGCCTGCCCTACCTGCTGCTGCTCCCGGCGCTCCTGCTCGAACTCCTCGTCCACCTCGTGCCGATGGTCATCGGCATCTGGATGGCGTTCAAGGAGATCACGCAGTTCTACATCGCCAACTGGGGCGACGCCCCGTGGGCCGGGCTCGACAACTTCGCCCTCGCCGTCGACTTCAACGCCCCCGTCGGCGAGGCGCTGCTCCGCTCCTTCTTCACCACCTGCCTCTTCACCGTCCTCTCGGTCGGCCTGTGCTGGTGCGTCGGCACCGCCGCCGCCATCTTCATGCAGGACAACTTCCGCGGCCGCGGCATCCTGCGCGCCCTCTTCCTCACCCCGTACGCGCTGCCGGTCTACGCCGCCGTCATCACCTGGGCGTTCATGTTCCAGCGCGACTACGGCCTGGTGAACCACGTCCTCACCGACCAGCTCGGGCTCACCGGCGAGCGGCCGTTCTGGCTCATCGGCGACAACGCCTTCGTCGCCCTGCTGACCGTCTCGGTGTGGAAGGGCTGGCCGTTCGCCTTCCTCATCGTCATGGCCGGGCTCCAGAACATCCCCAAGGAGCTGTACGAGGCCGCCGCCATCGACGGGGCCGGTGTCTGGCAGCAGATCCGCCGGATCACGCTGCCCTCGCTCGCGCCGGTCAACCAGGTGCTGATCCTGGTGCTGTTCCTGTGGACGTTCAACGACTTCAACACGCCGTTCGTCCTCTTCGGTGACTCCGCCCCGGAATCGGCCGACCTCATCTCCATCCACATCTACCAGTCGTCGTTCGTCACCTGGAACTTCGGCTCGGGCTCGGCGATGTCGGCGCTGCTGCTGCTGTTCCTGCTCGTGGTGACCGCCGCCTACCTGCTGGTGACCTCCCGCGGAAGGAAGTCCTCCGATGGCTGACACCACCCTGACCAAGACGGCGGAGCCCACCGGCAGGGCGAGCGGACAGCCACCCGCCGGACCCCGGTCCCGGCCGGCCCGCTCGCCGATGGCCTCGCCCCGCTCGTTCGTGTGGACCCGGTGGATCTTCCTCGCCGTGCTCACGGTCTTCGTGCTGGTCCCGATCTACGTGATGATCTCCAGCTCGCTGAAGCCGCTCCAGGACGTGTCGGGCGAGTTCCGCTGGATTCCCAGCGGGCTGACCGTCCGCCCGTACTTCGACATCTGGGAGACCGTCCCGCTCGCCAAGTACTTCGTGAACTCCCTGATCGTCGCCGGTGCCGCCACCGTCTTCTCGGTGATCGTCGCCGTCTTCGCCGCCTACGGCGTCAGCCGCTACCGCTTCCGCGGCAAGCGCGTCTTCACCGTCACCGTCCTGTCGACGCAGATGTTCCCCGGCATCCTCTTCCTGCTGCCGCTCTTCCTCATCTACGTCAACATCGGCAACGCCACCGGCATCGCCCTCTTCGGCTCCCGCGGCGGCCTGATCCTCACCTACCTGACCTTCTCGCTGCCGTTCTCCATCTGGATGCTCATCGGCTACTTCGAGTCGGTCCCGAGGGAACTCGACGAGGCGGCCACCGTGGACGGCTGCGGCCCGCTCGGCGCCCTCTTCCGGGTGGTCGTGCCCGCCGCCACCCCCGGCATCGTCGCCGTCGGCGTCTACTCGTTCATGACCGCCTGGGGCGAAGTCCTCTTCGCCTCCGTCATGACCAACGACACCACCCGGACCCTCTCCATCGGCCTCCAGTCCTACGCCACCCAGAACGACGTCTACTGGAACCAGGTCATGGCCGCCTCCCTCGTGGTGAGCGTCCCCGTCGTCGCCGGCTTCCTGCTGCTCCAGCGCTACCTGGTCGCCGGACTGACCGCCGGCTCGGTCAAGTAACCACCGCGCCTCCGCGCACCCCGTCCCGGCCCCGGCCTCCCGGCCCGCCGCCGGTACGGCGCCGCGCCCTGCCCCCACAGGCTCCCGAAAGGACCCGCACGTGACCACCACCGACCCCGCGCCGCTCACCGCGCCCGCCGCCCCCGACCTCAGCGGCCTGCCCGCCGGCTTCACCTGGGGCGTCGCCACCGCCGCCTACCAGATCGAGGGCGCCGTCGCCGAGGACGGCCGCGCCCCCTCCATCTGGGACACCTTCTCCCACACCCCCGGCAAGGTCGCCGGCGGCGACACCGGTGACGTGGCCTGCGACCACTACCACCGCTGGCCCGAGGACCTCGCCCTGATGAAGCGGCTGGGCGTCGACTCCTACCGCCTCTCGATCGCCTGGCCCCGCGTCCACCCGCAGGGCGACGGCCCCGTCAACGAGGCGGGCCTCGCCTTCTACGACCGGCTCGTCGACGCCCTCCTCGAAGCCGGGATCACCCCGAACGTCACCCTGTACCACTGGGACCTGCCCCAGGCCCTCCAGGACCGGGGCGGCTGGCCGGCCCGCGAGACCGCCGAGCACTTCGCCGCCTACGCCTCCACCGTCGCCGAACGCCTCGGCGACCGCGTCAGCCGCTGGGCCACCCTCAACGAGCCGCTCTGCTCCGCCTGGATCGGCCACCTCGAAGGCACCATGGCCCCCGGCCTGCGCGACATCGACGCCGCCGTGAAGGCCTCGTACCACCTGCTCCTCGGCCACGGCCTCGCCGCCCAGGCCGTCCGCGCCGCCTCCCCGCACGCGAAGATCGGCATCGTCAACAACCTCTCCACCGTCTATGCCGCCACCGACAGCGAGGCCGACCAGGCCGCCGCCCGCCGCATGGACGGCCACACCAACCGCTGGTGGCTCGACCCGGTCCACGGCCGGGGCTTCCCCGCCGACATGCGCGAGGTCTACGGCGTCGACCTGCCCGAACGCCCCGGCGACCTCGACACCATCGCCCAGCGCCTCGACTGGATCGGCCTCAACTACTACTTCCCGGCCGTCGTCGCCGACGACCCCGACGCCCCCCACCCGCACATCCGCACCGTCCGCCGCGAGGGCGTCCCGCGCACCGGCATGGACTGGGAGATCGAGGCAGGCGGCCTGGAGGAACTCCTCCTGCGTCTGACTCGCGAGTACGGCGCACAGTCCATCTACGTCACCGAGAACGGCTCGGCCTTCCCCGACACCGTCGCCCCCGACGGCTCCGTCCACGACCCCGAGCGCACCGCCTACCTCCAGGACCACCTGGCGGCCTGCGCCCGCGCCGCCCGCGCCGGAGCCCCCGTCGACGGCTACTACGCCTGGTCCCTGCTGGACAACTTCGAGTGGGCCTACGGCTACGACAAGCGCTTCGGCCTCGTCCACGTCGACTACCCGACCCAGCGCCGCACCATGAAGACCAGCGGCCACACCTACGCCCGCCTCATCGAGGAGTTCCGCCGCACCCGCTGACCGGGCACCGGCCGGAGCCGGGGCGGCCGCGCCTCAGGGCCGCCCCAGCTCCCGCCCGATCTTCCGCAGCTGCTCGAGGCGCTGCTCCAGCGTCGGGTGCGAGGAGAAGAGCCGGGCCATGCTCGTCCCCGAGGAGAAGGCCGGCACGAAGTAGAACGCGTTGTAGGGCTCGGCCTCGCGCAGATCCCGGGTCGGGATGCGGCCCATCTGGCCGGTGATCTTCGTCAGCGCCGAGGCCAGCGCCGCGGGTCGGCCCGTCAGCAGGGCCGCGCCCCGGTCCGCCGACAGCTCCCGGTACCGCGACAGCAGGCGCGTCAGCAGGAACCCGACGGCGTAGACCACCGCGCTGACCAGCGGGATCAGCATGATGAGCAGGCCCGCCTGGTTGTTGCCGCCGCGTCCGCCCCGGGCCAGGCCGCCCCAGAGGGCCACCCGGGTGATCACCCCGGCCAGGACGCCGAGGAACGAGGCGATCGTCATCACCGCCACGTCCTTGTGGGCCACGTGCGACATCTCGTGCGCCAGGACGCCGTCCAGCTCCTCGGGCTCCAGCCGCCGCAGCAGCCCGGTGGTCACGCAGACCAGGGAGGTCTTCTCGCTGCGGCCGGTGGCGAAGGCGTTCGGCACGTCGCTGTCGGCGATGGCCACCTTCGGTTTCTCCATGTCGGCCAGGGCGCAGATCCGGTCGACCGCCCCGTGCAGCTCCGGCGCCTGCTCCCGGGTGACCTGCCGCGCCCCCATCCCGTACGCCGCGATGGAGTCGCTGAACCAGAACTGGGCCACGAAGAGCCCGCCGACCAGCAGCACGATCAGCGGCCAGGAGCCGCGCGCCACCGCCAGCAGCACCCCCACCAGGACCACGTACAGCAGTCCGATGAAGAACATCGTCATGACCATGCGCGCGGTGAGCCCCCGGTCACCCGCGAACCGCGATCCCCGCCGACCAGCCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP014485|6615072:6655930|6630662_6630965_+|WP_079076086.1|DBSCAN-SWA
MRITAERLRAGLLTGTVNITPTENVPASGALGAYLRGTAAVTFPAGTFTETPRIFLTGRSSVPGVLIECNYTDQSESGFTITIARQTSTLTVVDWLAVAA
>NZ_CP014485|6615072:6655930|6638064_6638262_+|WP_079076087.1|DBSCAN-SWA
MATTVQELPQPTALGERQLRGTECVWCAGRLDTATAVDLGVRPDPQCPWASWFPRACPACAAGRS
>NZ_CP014485|6615072:6655930|6621874_6622408_+|WP_123985160.1|DBSCAN-SWA
MADLTEQEADDLLAEAAEMVHDYCGWRVWPRLVETITVDAVGGAVAGLPTMMLHEVSSVETRPPAATGPDAWEPVAGGWDWSEGGWLYRCGRWPDGPRRLRVVMESGYMEPPGAVGSVMLGIAARVRTAPVGVSSEQAGGESVSYGTSGASTDSGAGGQLTEAERRVLDRYRLENRP
>NZ_CP014485|6615072:6655930|6634273_6634558_+|WP_059213656.1|DBSCAN-SWA
MGELFGLKIADLGAVTLLALVVLMVLTGRLVPRRTYDDLKEERDTWRQAHVVSEEARAMERAQTRELLELGRTGAHALAGLRAAAADSEEVGTG
>NZ_CP014485|6615072:6655930|6655012_6655930_-|WP_008413611.1|protease|DBSCAN-SWA
MAGRRGSRFAGDRGLTARMVMTMFFIGLLYVVLVGVLLAVARGSWPLIVLLVGGLFVAQFWFSDSIAAYGMGARQVTREQAPELHGAVDRICALADMEKPKVAIADSDVPNAFATGRSEKTSLVCVTTGLLRRLEPEELDGVLAHEMSHVAHKDVAVMTIASFLGVLAGVITRVALWGGLARGGRGGNNQAGLLIMLIPLVSAVVYAVGFLLTRLLSRYRELSADRGAALLTGRPAALASALTKITGQMGRIPTRDLREAEPYNAFYFVPAFSSGTSMARLFSSHPTLEQRLEQLRKIGRELGRP
>NZ_CP014485|6615072:6655930|6653596_6654979_+|WP_010639655.1|DBSCAN-SWA
MTTTDPAPLTAPAAPDLSGLPAGFTWGVATAAYQIEGAVAEDGRAPSIWDTFSHTPGKVAGGDTGDVACDHYHRWPEDLALMKRLGVDSYRLSIAWPRVHPQGDGPVNEAGLAFYDRLVDALLEAGITPNVTLYHWDLPQALQDRGGWPARETAEHFAAYASTVAERLGDRVSRWATLNEPLCSAWIGHLEGTMAPGLRDIDAAVKASYHLLLGHGLAAQAVRAASPHAKIGIVNNLSTVYAATDSEADQAAARRMDGHTNRWWLDPVHGRGFPADMREVYGVDLPERPGDLDTIAQRLDWIGLNYYFPAVVADDPDAPHPHIRTVRREGVPRTGMDWEIEAGGLEELLLRLTREYGAQSIYVTENGSAFPDTVAPDGSVHDPERTAYLQDHLAACARAARAGAPVDGYYAWSLLDNFEWAYGYDKRFGLVHVDYPTQRRTMKTSGHTYARLIEEFRRTR
>NZ_CP014485|6615072:6655930|6615072_6615522_+|WP_158516863.1|terminase|DBSCAN-SWA
MRGPLKIPKHLQAVPDPGAAAGTVAERVDASAPPKPPGFPDDPEMAALWDAIVPELDRAGLLTRADGPTVELAIRHFLAARKAGNALQAGEVVLDDPAHGGTAKKNPAGAEMRSQSQLFLEYAKQLGMSFAARARMPAKDEATEVNPFA
>NZ_CP014485|6615072:6655930|6620328_6621549_+|WP_061405299.1|capsid|DBSCAN-SWA
MNLHEQRQTALKAARDVAEKARDEGRVLTEDEQTTVKGHLATADDCAEKIKQAAESDALFKRAFAVEDGKPSGGGSAPVGVKAKLEADAAYKSATLAASSRTRFSQRTTEFEAKDFSTGGPAGGLVQTQYGQVVPETLRRPTVAQLLGSGTMSATTLTYYVQGPSAGDFAVVPELGEKPAIDFDFEPEVETLSKIAGITKISDEAFQDTAYLVSVIESQMRLRLVLAEEAQLLNGTGTGGNMTGLLNRSGILTEASASADDDLDAIFRGMTAVELATQLPVDAVVINPLDYQRLRLSRDANEQYFAGGPFTGAYGNNGIQMSPGVWGQNTVVTSAIAQGTVLVGAFAVGGQVLRKGGVSVEMTNSDADDFRHNRVAIRVEERLMLAVYQPSAFCEVTLFAEDEGGA
>NZ_CP014485|6615072:6655930|6615641_6617399_+|WP_079076085.1|terminase|DBSCAN-SWA
MVAVAVKLPGKRELARLKLSPEVAWYLLDRGYELPNCPPQHKTPEPREVEGAFFDPARVDRVVDAFARLRHTQGKWSGRPITLRSWQIAYLIGPTYGWVRPTEDGRTARIIQTQYLDIPRKNAKTTIGGGQCIYLTCADGEAGAQVYALATRKDQARLCFDPVRLLAAHAPDLKGHVKPMKDKILHPRSGSYFSVMSSAGEAMHGTSPHAAFVDEVHLHKSRDLIEAVETGTGAREQPLIMYATTADAGSPFTPYAEIREYCEKLARGALVDPTFYGVVFAAGRGDDPFAPETWLKANPGLAAGDSPTMESMEKAAAKARQNPLELASFLRLRLGIRTKQESKFISLSEWDRNAGMVDRAALRRAECYGGLDLAATSDLSAFCLVFPNGPPASGIEGYQALWRLWTPQANLWKLNERTAGAADVWVREGWLTVTPGEVMDYDHIRQAINQDREVFNVQEIAYDPWNSTQLVSDLLSDEAPLVEFRQGYRSMSPPLKELARLLRQGTPETPLLRHGGNPAMRWQIDNLAVVSDPAENVKPDKKHSADKIDGVVSLIMALDRARNRKPLRRSAYDDDDDYDDEADVA
>NZ_CP014485|6615072:6655930|6640364_6640604_+|WP_061405323.1|DBSCAN-SWA
MDVHLVEARLPGGVLAWADRRRTQAVMYVHPDLASGGALSAAGRHLVRESLDASVGVGWRLGGGVPDFALPGPPLSWGK
>NZ_CP014485|6615072:6655930|6624541_6624892_+|WP_061405307.1|DBSCAN-SWA
MGLDLDDIGAPHLTWGRLWRLVQVIPKTSRSALAWAKSRESGVYPLDIELAAGHFDALSVANWQRSKKASSAGSAPKPLPRPSKIEATRGEARDRLIDRGRALLRRQRPRPKPRTS
>NZ_CP014485|6615072:6655930|6638680_6638953_-|WP_107251623.1|DBSCAN-SWA
MTAAYAAQSVCRVPPQDHPAWLHAERRALGDRIRERRMRQNLTQEKLAEAAGVSRDTVQRIERGTNDPRYSDLARIACALDTPLAKLVGG
>NZ_CP014485|6615072:6655930|6650220_6651540_+|WP_061405328.1|DBSCAN-SWA
MRRFRAACMTATVTALATVVAGCGGGTSTSGDGGADKPKELVYWASNQGPSIEADKKILTPRLKKFEQETGIKVKLEVVPWSDLLNRILAATTSGQGPDVLNIGNTWSSSLQATGALLPWDDKNFDKIGGRDRFVDSAVGSTGAEGQDPAAVPLYSLAYALYYNKAMFEEAGIDKPPATWDEMVTVGKKLSKDGKWALGAEGSNLSNNIHQVFVLGQQHGADFFDAEGKPDFTSDGAVAAVKQYVDFMAKDKITAPGNAEYAQNQSLQDFAKGKTAMVLWQAAASTFKSHGMAEDDFGVAPVPVASGTPGTGEQVNSMVAGINIAVFKNSKNLDGATKFVEFMTSDTEQVHLNKTYGSIPPVKAAQQDKAFDRPDTAVLRDTLLESAAPLPQVPNESQFETAVGTAVKELFADAAAGRAITDEAVKTRLAKAEQQMPKQ
>NZ_CP014485|6615072:6655930|6627245_6630623_+|WP_061405309.1|DBSCAN-SWA
MAWPDRPQKLPLRTELAFGADPAGDPATWTWTDVSEHVEDQSITINRGRGEEGGETRPASTGLELVNNGGDYTPGHAGGAHYPHVRLGVPARLSVQAGGPHLRLPASGAHAVTGTTSGLTVTDLDIRAEVALDRVAAQFRDVTPGGRRPWQTIAQEITGRSRTDGTLMWHLAADMQGGLLLMWTTASEARQDRSSTDVLPYGSGQRFAARATLDVNNGDGGHTVTFYHAPTMDGPWEILGQPIVTSGTTTILQTDATPLRLGRVTTENRLGAVGRLYRAELRNGINGTILASPDLRTVAPGTTSWTDSTGKAWTLAENAEITDWVPHVTGTVDEWAPHWPWGDLSTPGYDGEARTDVTVSGILRRLGTGQPPLQSALRRRLPAGNPFAYWPLEDEPGATSGASGLDSGKPLNVSGLRFGQSTSLLSSDALPTVTAGARIRANLRAGAQGEWAVTMLYNLAQLPQNDSVFFEVQADRGVWTSYRITLRSNSVVCDAIDDSGSSSSTTRLFNVLTSTFYGGWRRFTLQATQTGNTTEVRGIWRFLDGDGGGSGGGTFTGSAGVLSRIDTTFGAELEGMAIGHLSVMRRADVWVYAAAEDGFAGETALARMRRLAEEERMPLSVIGVEASSPAMGPQRIATLLDLVQECVDADGGILTELRGQPGLQYRSRESLLNQRPALVLDAQANEIAAPFSPVLDDQRTRNRITVSREGGSSATVEDAESIAESGIYDASAQLNVAYDTQLEALAGWRLHLGTVRGMRYPQVGADLAIAPRLIDGWLSVDSGTRMDVTGLPPQHPQGTVPLMVEGTTETITPTRWTVRATCSPASPWTAGVVGDDQLGRVDTDGTVLAGPVASADGAILTRVTAGPTWTRAASELPYVLNADGEEVTVIAVADVFDTFQRTVTGGWGTASGGLPWLLGGGAAAERSVSAGRGVVTVSSATISAVRIQALAGPLGDAEVRVRMSVPQVSTGAALIPGVLLRYADGSNYYRARLHFNAGGTLSTSITRTVTQVGSTVTVSGGYTAGAEFEVRARVDGHRLRMRVWPVGGTEPTIWHQDQTITTDPIEHGLVGVTAGGFTGNTNVDPQIRFDLFEAVGVQRMTVTRPDPQDHAAGGDVRLAQPAIVI
>NZ_CP014485|6615072:6655930|6634760_6635084_+|WP_061405316.1|DBSCAN-SWA
MSFAQLLNTSVSALVALSAAVFVVTYHRLAPWRSTPMGWHLMLLAATLGLLGLYTVVITIVGLDGTPATVLRIVRAGLLLLVAGLLAQRTLMVTRAQRPEGDPHARP
>NZ_CP014485|6615072:6655930|6648785_6649967_-|WP_061405327.1|DBSCAN-SWA
MSRQALGPATGLSSGSISNVVTELAAEGLVEEAGHVESDGGRPRTLLRVAPRAGYLIGIDIGETRVRAELFDLAMTELARCELPLTGGARDIDTVIAHTARSIAAVLEESGIAAEALTGIGVGVPGIVERTPEGAVVHGQTVGWDAVPLERLLRGATDLPPATAFHISNGTMALGQAEMWYGGGRGTTDAAIVLFGSGVGACIVTDGQIHGIDHGTPAEFGHLTVQVRGRICRCGSRGCLEAYTGAQAILSRWHEAGGPDPDEATEEYGISRLLAAARPEAAGAEADPTALAILDDTAEYLAAGLADLVNLFQPQRILIGGWAGLQLGPLVLDTIRERTRGYALHHPGRHTEITLSTLGPDAITQGAATLPLNHLLHHTTTAQPPVPAERLPR
>NZ_CP014485|6615072:6655930|6639031_6639961_-|WP_123985164.1|DBSCAN-SWA
MSPEQIAAYRAIAIGNPPEAGPATEQLAELGLIEWRPHEETWVAHDPRATARGLMGEALEELAELVTRIRRVPALDALASDYDPHRMYGGPASEFLASRAAMNDRIGQVAASTSISIMTAQPGEPADRDPQIVALGVQRTIDVLHAGTEVRGLYNSLAAAHPQTAASIDAMVDAGSAARTMSGSFPRMMIFDSRHLFIDNHVVSGAEADSGWHVTDRGSVAWAVHVFDALWNRAARWSSVPVGGATTGRQRQILVELEAGYTTQQAARRLGLGERTITKELSALRSALGMRTLYQVMAWWATSPDRDLP
>NZ_CP014485|6615072:6655930|6635719_6635956_-|WP_061405317.1|DBSCAN-SWA
MDIPDSLIDLQRAADAEWARLAELTDNDERERQRRVWFEAGARAQAAITEWAVAENKNRYKVEKAVREAVRHPESGSD
>NZ_CP014485|6615072:6655930|6619477_6620332_+|WP_061405298.1|head,protease|DBSCAN-SWA
MQVKDAPALRVKVTEVDTEGGPEAPGTGEFTALVSVFGNVDSYGDVVMPGAFDRSLKEWSASGYPIPVYWGHNLSDPDYNIGSVIDAVETERGLQIRARLDMDSPKAPQVYRLLKGGRVKEFSFGYSVRDAGWGTKDGAEVFELRDIDLYEVSVVPVGANPATELQTVKALGERTERAAARALEGVKAGRALSGKNESALREVRDQLAVAIEGIDDVLSALDPPESPAEDEDDEKKSQEEDPATEREPADDEEPDGAKSIEPMPDFAADPLAAIIEIETRSAQA
>NZ_CP014485|6615072:6655930|6642005_6643997_-|WP_061405325.1|DBSCAN-SWA
MAPLPHRPDAAPPARIGLDRAEAVVVERYARLVRLAHLVLPPALGRHRRVLLAHGVVQRALPGLTTGRGQVPVPDGSTDPVGYAWVRGQVLSAALAFEHRPRLWPRRLPPPRALRPGLPAVWGLRFFPRAGGTEELALDRVLAEVSAPARAAFALDALEELGTEDVAALLAAAGVADPEAALKEAAGVRARTGEAAGVLLASQEFDPCQVQTRPTDLLSRRRKGRLVGVGLVAVAASCALAVSGPAPAPGPEVSEADGKGGVAPVAEARGGTPALNPALLRRTDAAQWADTARVDFTAWPPRGGRTEDTELLGRALRAWSSPEAAGVKLSRSRTTPAVPPAGPPRLLYAGDVAGAAVVLLHDGSRAARYAEPLNGSSPPSLEVARTDEADVTTAAALVVSRTESGVRFLLAPWVGEAKTRDLLRPGGDARKLRVDEDGVTEAVAGPPVAGAACERWPVVRLRSSPRVVEDHAFLVTDLGELTAAHLSYTPLPGSGAGARAPREATGETALAAWARVGCRLAGLERSGVRSVNTWDFAEQTLPEEAGRAVWGCTRVSTWQGPGHVLVHLRPEAGRAAVRLVGETGPTAACSRFGQHLVASTAWRAPSGRWYSLAAGSREVRALTVSGHERERGRTAAVRTDGEPDPRVTGHLSGGDELTELEYR
>NZ_CP014485|6615072:6655930|6632806_6633622_+|WP_079076059.1|DBSCAN-SWA
MAPPMTPATFLAALKAEGVTVVEVGSWRTHNRNSKGAWGPLNGVMIHHTVTSGSARTVEICRNGYSGLPGPLCHGVITKDGRVHLVGYGRANHAGAGDDDVLSAVIAERALPKPDEANTDGNARFYGFECENLGDGKDPWPAAQLDAIERVSAAICRMHGWDAASVIGHLEWQPGKVDPRGFTMSSMRDRIERRLSAPPGKTPTPTTPDKETPMSYRDVWEQDAAPAPDSSPTKKTNPTWKPISFLREIYDLARETRDLVRDIRDQQKRGS
>NZ_CP014485|6615072:6655930|6652656_6653496_+|WP_003946779.1|DBSCAN-SWA
MASPRSFVWTRWIFLAVLTVFVLVPIYVMISSSLKPLQDVSGEFRWIPSGLTVRPYFDIWETVPLAKYFVNSLIVAGAATVFSVIVAVFAAYGVSRYRFRGKRVFTVTVLSTQMFPGILFLLPLFLIYVNIGNATGIALFGSRGGLILTYLTFSLPFSIWMLIGYFESVPRELDEAATVDGCGPLGALFRVVVPAATPGIVAVGVYSFMTAWGEVLFASVMTNDTTRTLSIGLQSYATQNDVYWNQVMAASLVVSVPVVAGFLLLQRYLVAGLTAGSVK
>NZ_CP014485|6615072:6655930|6624173_6624503_+|WP_061405306.1|DBSCAN-SWA
MSHGKTTFDLAELRQRAAQRKGGDKLTITIDGKPYTIPVPGFWPDRVKELARRSREDGDVPFVRELMGAEKYEKFVAAGGRSDDVALLLEEYKQAQGADLGESSPSPTS
>NZ_CP014485|6615072:6655930|6635070_6635244_+|WP_158516866.1|DBSCAN-SWA
MPDPEPRPAERRIDPAAGDTAALAALGLADPVPIPSADPFREPVYPDGPWPGPDDED
>NZ_CP014485|6615072:6655930|6648210_6648687_-|WP_003946783.1|DBSCAN-SWA
MQKITTNLWFDGQAEEAAAFYTSLFEDARILGVERFTDAGPGEPGSVVTVTFQLAGQEFVAINGGPEFTFTEAISLSVDCETQEEVDRYWAALTADGGEEVQCGWLKDKYGLSWQIVPRALVELLASSDREAATRATRAMLEMKKLDIQALRDAAAGL
>NZ_CP014485|6615072:6655930|6640124_6640328_+|WP_123985165.1|DBSCAN-SWA
MSMKLRIALAAAALAAAAAVTPLATASADPAPAPPAAADDIGWGAPGKNPTPSPSPTATPAGDIGWG
>NZ_CP014485|6615072:6655930|6622404_6622755_+|WP_061405302.1|DBSCAN-SWA
MSFGWHRDTIVRVRAPLTTDPYGNPRRDWAAAERTSMPGWRVQPVQGARQTAAETIPREGLERSKRLFGPISADIESTDRIEWQGEVWVIDGDVDRWRGPTGRLAHTELLMQRMEG
>NZ_CP014485|6615072:6655930|6651548_6652568_+|WP_037841446.1|DBSCAN-SWA
MTATAARRPAASGPGAAGAGRPSPGPAGARRRPRIPARLRKIGLPYLLLLPALLLELLVHLVPMVIGIWMAFKEITQFYIANWGDAPWAGLDNFALAVDFNAPVGEALLRSFFTTCLFTVLSVGLCWCVGTAAAIFMQDNFRGRGILRALFLTPYALPVYAAVITWAFMFQRDYGLVNHVLTDQLGLTGERPFWLIGDNAFVALLTVSVWKGWPFAFLIVMAGLQNIPKELYEAAAIDGAGVWQQIRRITLPSLAPVNQVLILVLFLWTFNDFNTPFVLFGDSAPESADLISIHIYQSSFVTWNFGSGSAMSALLLLFLLVVTAAYLLVTSRGRKSSDG
>NZ_CP014485|6615072:6655930|6624944_6627236_+|WP_158516865.1|DBSCAN-SWA
MQITPSFQGFGSNIMSEVGRELSSGAGRAGEQAGEAAGREFGSSFEERASAAAERMGPIGTAAGVGIAGALGVGLAAAMDASSATAKLTAQLGLTEAEAARVGAISGEVFSAGFGESMGEVSEAVGAVTSSVADLGATSDAELQQLTTTALGLAETFQWDVGEAATAAGNLVKNGLAKDATDAFDVMSQAAKTLPASMRADIPAVVSEYGIHFARIGLDAKTAFGMMSQYVEAGGRDIDQAADVLHEFGRITSEETDRAAEGFKALGLDSSQMLSDIAKGGEPAEAALTATLDALRGVKDPAEQSALAVELFGDMAGEGVDALWAMDPATAAAASGMDKTAGSGKELTDALAADPARVFEGAMRDLTMSLAQELAPALAGVAGWVSDNEGAFKGIVFAVGGIALAVAGATAALRLYQGAIVAVRVATAIWTGIQWLLNAAFWANPMTWVVLGIIALIAIIVLAIVYWNEIVAAVRAAWQWITEATGVAVEWLKVKLGEAWEWIKTTASAAWEAVKATIGGAWQWIKDQTGAAVDWVATKAAAAWEGIKGAAKAAWDGVVLILKLAWATIVQIAAGAVLGLITAISGAWSTIKRATSTAWATVKRSITDAVGRAYDSVKNAGSRFLSVGRDIVNGIVTGVRNAAGRLFGSLRDMASNALSAAKNALGIGSPSRLFADQIGQWIPAGVEVGIDAGQGELDQRVERLVQTPDVPVVRASVATGAAASPAPVVIRADGGRASRVLLELLQQSIRTDLGGDVTRLGTR
>NZ_CP014485|6615072:6655930|6634554_6634764_+|WP_123985163.1|DBSCAN-SWA
MKWPWRRRHGGRSPGQAAADRALHRARADRQEAADRQPAVQETAETLRRYREENHFAQLFRASIEGRRA
>NZ_CP014485|6615072:6655930|6645332_6645962_+|WP_061405326.1|DBSCAN-SWA
MAARIEHLVTSGTFSLDGGTWDVDNNVWIVGDDTEVIVIDAAHDAAAIAAAVGERKLVAIVSTHAHDDHIDAAPALADRYGAPILLHPDDLVLWDQIHPARRPDADLADGRQITVAGTTLTVLHTPGHSPGAVSLYAPELHTVFSGDTLFQGGPGATGRSFSDFPTIVASIRDRLLTLPEATVVRTGHGDTTTVGEEAPHLDEWIARGH
>NZ_CP014485|6615072:6655930|6623448_6624087_+|WP_061405305.1|DBSCAN-SWA
MAKDTANARAWYGFDSGLWVTLPGEPMPDLDEIPDVYDEAGVFQPPGEAFYEVGWLSEDGPTQGRNRTVERFRGWQGNSIVRTAVTEDDHTFQIQALEDNWVVASLRYPDSVVTTTAGITKTVVQQQSGEDVRTGVLDLVDGGIWKRILIPNLVVDEMGDTSHTAGELTFYEMTLLAKVTSLSVDGVVRGVSLIEVTNNPAAIRPTVPDPTP
>NZ_CP014485|6615072:6655930|6623041_6623431_+|WP_061405304.1|DBSCAN-SWA
MAAPVVAWPDVTLLATQYLRDRLGGVQVGSRIPRPRPVEFVVLRRVGGPRRNPLVDDARLDVQVWAETDERAMEIASLARYQLGLMPQHVPAVRQFGEDAGPNLIPDAPSDVPRVLLTVVLSVRGAVPT
>NZ_CP014485|6615072:6655930|6644247_6645333_+|WP_003946786.1|DBSCAN-SWA
MAQHVRGVIARAKGEPVELTTIVVPDPGPGEAVVDIQACGVCHTDLHYREGGINDDFPFLLGHEAAGVVESVGEGVTEVAPGDYVILNWRAVCGQCRACKRGRPQYCFDTHNAKQKMTLLDGTELTPALGIGAFADKTLVAAGQCTKVDPAASPAAAGLLGCGVMAGIGAAINTGNVGRGDSVAVIGCGGVGDAAVAGARLAGARRIIAVDIDDRKLEKARSVGATHTVNSREADPVEAIRELTDGFGADVVIEAVGRPETYRQAFYARDLAGTVVLVGVPTPEMNIELPLLDVFGRGGALKSSWYGDCLPSRDFPMLIDLYLQGRLDLDAFVTETVGLDDVEEAFARMHGGDVLRSVVVL
>NZ_CP014485|6615072:6655930|6646128_6648144_+|WP_008414983.1|DBSCAN-SWA
MSFASTPSSSLPSQSPPAAPHMVVCGDDALAQRLAAELADVYRVRVVLLTPAGSESRSPGLPGAARPPGRASLLLGRVSSVMNRNGGPATANGPTPPPAPQEPRRSGQVRVVDAPAPDDEAFAVARVHTAEALALVYDDDETNIHAALRARRLNPRLRLVIRLYNRKLGQHLEELLEQAAHLAGLEDVDAGVTVMSDADTAAPALAAAAVAGSSKVVEADGILLRAAERDPSLPRRPGDPPPVTLALLSATVSDPAGSEGSDSDGDTPTLLPDDTDVADSQSSRATVVLERVGTSVPQLPRRRLRRRLRGRGAPLGSLFSRQLRWSVAGLVAAVCVLAVVAIVTTDERPLHAMHMTLLDLLAINEPAVEDGEVLTRKILQLLASVVGMLLLPFLLAAVLEALGTFRTATHLRRPPRGLSGHVVLLGLGKVGSRVLSRLHEMEVPVVCVEEDPEARGIALARRLRVPTVIGDVTEEGVLEAAKVHRARALLALTSVDSTNLEAVLYARGVKQDLRVVMRLFDDAFATAVYRTLRAAHPQARTRSRSVSTLSAPAFAVAMMGRQILGAVPVERRVLVFAALDVAGHPEFEDRTVEEAFRPGSWRVVALDAARPDERRDHLGAVPGERRPPTLAWDIHPGYVLRAQDRVVLVATRQGLGELLGRQGMTDPAGRF
>NZ_CP014485|6615072:6655930|6621621_6621807_+|WP_061405300.1|DBSCAN-SWA
MARLEEYEVDIASGVTVTMKLSPDAAEKADPKRVRKVTRAKGRPVANKVRRPANKSATSES
>NZ_CP014485|6615072:6655930|6622757_6623042_+|WP_123985161.1|DBSCAN-SWA
MARARVRVEINYDGIGELARSGGVRADLERRAQAVRAAAQAAAPRMQEGRIEIEASTRVGRDRARGIVVAQHPGVLHAEAKHRFLGGAMDAAGD
>NZ_CP014485|6615072:6655930|6617412_6619461_+|WP_158516864.1|portal|DBSCAN-SWA
MGFWSRVKSLAWWGSRPSSGSWDRRGWSWLPLDQSYVLGMEPAELWRTQPHLRTVTDFIARNVAQLGLHAYDRRGDTDRRRVRGEGVAALLRRPNADMTTYELVYGTVADLALFDRAFWWVKRSASAPSGWEIRPIPSAWVVQGVGGTVFAPADWIVQPPHGAEQLTIPAAQMLVFHGWNPSDPSAGSSPVAALKLILSEQVHAYQYREQVWQRGGQPSAVIERPMDAPQWGSKGKARFKQEWQDSYGRSGPEAGGTAILEDGMKLVKTGFSAREDEFVAAATLSLTTVASVYQVNPTMVGVLDNANYSNVREFRRSLYGDSLGPWLTMLQDRLNGFLLPMLGEPEDRYVEFNLAEKLRGSFEEQAAVLQASVGRPWMTADEARGLQNMPALGGDAEELVTPLNVLVGGQASPQDSAPPPTLASDAPPREASGAGLVRGKARKVRADPVRADDFEARYERGLTRWFDDFTSAVLAGYGSAKRGPVRVKAAEDFVDREEWQASLADLLLTLGLATSTAAAEALLEQVGLPPEDYNAEATVAWLTAMAAGVAEGIVGATLAEADEALADAERTDEDGEPMPPEARLAAALAAAAGSRVPEIASSQVTALSGFGQAEAARGAGGGATKTWRVRSTNPRPAHRRMDGETVPLDDRFSNGARWPADSSLDDADRAGCKCAVEIEFEF
>NZ_CP014485|6615072:6655930|6633621_6633966_+|WP_061405314.1|DBSCAN-SWA
MPILNLTPHPIRLYANEREDGTDDLDPHLREVYAPEPTPARLATFEVSSGMWPVLVEFGHAQNLPPKRDGYQYIVSLVVALALATRRGDLLVPYREVRNASGTVIGCRSFAQPV
>NZ_CP014485|6615072:6655930|6636148_6636685_-|WP_061405318.1|DBSCAN-SWA
MTTLYLFGSAAPPVLGVGTVIEDAQQRGFDVCLGLTPTAARWLEPQTAELERLTGHPVRSEYKAPGTADAWPKADVVLFAPATFNSINAWALGITSSFVVGVCAEGIGKGIPLVTMPCVNAAYAQHRALDRSVAELRDMGVSVLYGEGGFQPNPPGEGREFPWRVAFDEVERAVGAGR
>NZ_CP014485|6615072:6655930|6636817_6637987_+|WP_061405319.1|DBSCAN-SWA
MPTPDDDSTGGRIRRERRRARLSQRQLADRIPFSYSLLNQVECGARAASTELVAAVAAALRIDVSLLTGSAVTDQLPGQRADIVRPIREALDLYDLAPDVERPTRPVAAMVEAADRVCQQVRATHLRTAASALPDLIADLTHVALTSPSTEGWRALASTYRSAHDVALKLEHRDLAALALERMGWAAERASDPCLAAIRQYKRALSWQDSELGLRLVQAGHDTLDGQSSREALAVAGQLHLGASAVAARARDRAGVARHIEAARELAARTGPAQSIHWLGFGALNVRLHAMGAAITMRQYDDALQQARALRIPPSAMTSRRARFLVDRAMAEMETGLGDTSLRHLVEARAVAPEQTRYLPRTRETVRGLLHTTRRPSERLTRMAAWVGV
>NZ_CP014485|6615072:6655930|6640971_6641985_+|WP_061405324.1|DBSCAN-SWA
MKAAVVRSFTEPLVVEEREVPEPAGHQVLVRMETSGLCHTDIHAAHGDWPIKPSPPFVPGHEGIGVVEARGDQVDHVQVGQRVAIPWLGEACGHCEYCVSGWETLCLQQQNSGYSVDGSHTEYALAHGTYVVPVPDGIDPLDAAPLTCAGVTTYKAVKLSGARPGKRALVSGIGGLGHLALQYATIFGAETIAVDITDEKLQLARDLGADHVVDARTQDVAEEVRRLGGADAAISLAVSNDSFRAAYDSLNRGGTLVLVALPPEGELSIPVFDTVLNGTTVTGSIVGTREDLVEVFRLHQLGRTRVVRETRRLEDINTSIDEVLDGKVTARLVFDLR
>NZ_CP014485|6615072:6655930|6633979_6634240_+|WP_061405315.1|DBSCAN-SWA
MADHISLPDAQTVVKTGAAYARDLAERTAATFLQAFVGGVVLTQPFDLAMWQAAAVGGVAAAGALLKGLVARWRDVTNSASLAKGV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158516863.1|6615072_6615522_+|terminase	P27 family phage terminase small subunit	NA	NA	NA	NA
WP_079076085.1|6615641_6617399_+|terminase	terminase large subunit	A0A1B3AYP7	Gordonia_phage	1.7e-178	54.7
WP_158516864.1|6617412_6619461_+|portal	phage portal protein	A0A1D8ESX2	Arthrobacter_phage	1.1e-141	44.2
WP_061405298.1|6619477_6620332_+|head,protease	HK97 family phage prohead protease	A0A0U4JG80	Arthrobacter_phage	9.5e-50	50.7
WP_061405299.1|6620328_6621549_+|capsid	phage major capsid protein	A0A2R4A112	Microbacterium_phage	6.3e-71	53.6
WP_061405300.1|6621621_6621807_+	hypothetical protein	NA	NA	NA	NA
WP_123985160.1|6621874_6622408_+	hypothetical protein	NA	NA	NA	NA
WP_061405302.1|6622404_6622755_+	hypothetical protein	NA	NA	NA	NA
WP_123985161.1|6622757_6623042_+	hypothetical protein	NA	NA	NA	NA
WP_061405304.1|6623041_6623431_+	hypothetical protein	A0A2H5BLS0	Streptomyces_phage	1.8e-16	38.6
WP_061405305.1|6623448_6624087_+	hypothetical protein	Q6VY45	Streptomyces_phage	2.2e-14	30.6
WP_061405306.1|6624173_6624503_+	hypothetical protein	NA	NA	NA	NA
WP_061405307.1|6624541_6624892_+	hypothetical protein	NA	NA	NA	NA
WP_158516865.1|6624944_6627236_+	hypothetical protein	A0A142K643	Streptomyces_phage	3.8e-93	53.0
WP_061405309.1|6627245_6630623_+	hypothetical protein	D7NW64	Streptomyces_phage	4.7e-108	34.4
WP_079076086.1|6630662_6630965_+	hypothetical protein	NA	NA	NA	NA
WP_079076059.1|6632806_6633622_+	N-acetylmuramoyl-L-alanine amidase	A0A1J0MCN5	Streptomyces_phage	1.8e-82	69.8
WP_061405314.1|6633621_6633966_+	hypothetical protein	NA	NA	NA	NA
WP_061405315.1|6633979_6634240_+	hypothetical protein	NA	NA	NA	NA
WP_059213656.1|6634273_6634558_+	hypothetical protein	NA	NA	NA	NA
WP_123985163.1|6634554_6634764_+	hypothetical protein	NA	NA	NA	NA
WP_061405316.1|6634760_6635084_+	hypothetical protein	NA	NA	NA	NA
WP_158516866.1|6635070_6635244_+	hypothetical protein	NA	NA	NA	NA
WP_061405317.1|6635719_6635956_-	hypothetical protein	NA	NA	NA	NA
WP_061405318.1|6636148_6636685_-	flavoprotein	NA	NA	NA	NA
WP_061405319.1|6636817_6637987_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_079076087.1|6638064_6638262_+	hypothetical protein	NA	NA	NA	NA
WP_107251623.1|6638680_6638953_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_123985164.1|6639031_6639961_-	hypothetical protein	A0A142K655	Streptomyces_phage	6.2e-55	40.1
WP_123985165.1|6640124_6640328_+	hypothetical protein	NA	NA	NA	NA
WP_061405323.1|6640364_6640604_+	hypothetical protein	NA	NA	NA	NA
WP_061405324.1|6640971_6641985_+	alcohol dehydrogenase AdhP	NA	NA	NA	NA
WP_061405325.1|6642005_6643997_-	hypothetical protein	NA	NA	NA	NA
WP_003946786.1|6644247_6645333_+	S-(hydroxymethyl)mycothiol dehydrogenase	A0A0K0KVL7	Prochlorococcus_phage	5.4e-34	29.5
WP_061405326.1|6645332_6645962_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_008414983.1|6646128_6648144_+	NAD-binding protein	NA	NA	NA	NA
WP_003946783.1|6648210_6648687_-	VOC family protein	NA	NA	NA	NA
WP_061405327.1|6648785_6649967_-	ROK family protein	NA	NA	NA	NA
WP_061405328.1|6650220_6651540_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_037841446.1|6651548_6652568_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_003946779.1|6652656_6653496_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_010639655.1|6653596_6654979_+	beta-glucosidase	A0A0B5JD41	Pandoravirus	4.4e-65	35.4
WP_008413611.1|6655012_6655930_-|protease	zinc metalloprotease HtpX	NA	NA	NA	NA