CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014955	Mycobacteroides abscessus strain FLAC013 chromosome, complete genome	1 crisprs	cas3,csa3,DinG,DEDDh,cas4,WYL	0	2	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014955_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014955_1

305910-306146

Orphan

Consensus_repeat	Method
GCCGCCNTTGCCGCCGGN	CRT

4 spacers

DEDDh

The CRISPR arrays of NZ_CP014955_1

>merge|NZ_CP014955|1|305910-306146|CRT
GCCGCCCGTGCCGGCCGACACGTCCATCGGGTGGGTGCCCAGGGACAGGTCGTGCTGGCATTTGACGAGGATGGCGCCGCCGTTGCCGCCGGTACCGGCGAAATTTCCGTCTCCGCCGCGCCCCCCGGTGCCGCCGTTGCCGCCGGTTCTGCCGAATTCGCAGTCGTCCCCGTCGCCGCCTTTGCCGCCGGTGCCTCCGGTTCCGCCTGCTCCTCCGTGCCCGCCGTTGCCGCCGCG

>NZ_CP014955|1|1|305910-306146|CRT
GCCGCCCGTGCCGGCCGA	CACGTCCATCGGGTGGGTGCCCAGGGACAGGTCGTGCTGGCATTTGACGAGGATGGC
GCCGCCGTTGCCGCCGGT	ACCGGCGAAATTTCCGTCTCCGCCGCGCCCCCCGGT
GCCGCCGTTGCCGCCGGT	TCTGCCGAATTCGCAGTCGTCCCCGTC
GCCGCCTTTGCCGCCGGT	GCCTCCGGTTCCGCCTGCTCCTCCGTG
CCCGCCGTTGCCGCCGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014955.1\|WP_005083669.1\|298324_299599_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP014955.1\|WP_005083649.1\|307262_307973_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP014955.1\|WP_005065334.1\|300556_301141_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP014955.1\|WP_005112973.1\|310631_311690_+\|phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|270703
NZ_CP014955.1\|WP_005087054.1\|302526_303348_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|119339
NZ_CP014955.1\|WP_005063138.1\|305086_305695_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_CP014955.1\|WP_005115713.1\|313858_315052_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP014955.1\|WP_005063151.1\|315052_315301_-\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|184031
NZ_CP014955.1\|WP_005083648.1\|309313_309898_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291
NZ_CP014955.1\|WP_005121857.1\|296886_298257_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP014955.1\|WP_005063148.1\|312903_313887_+\|DEDDh-family-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|180377
NZ_CP014955.1\|WP_005072474.1\|307969_309238_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_CP014955.1\|WP_005083666.1\|299595_300570_-\|phosphotransferase	unknown	unknown	gnl\|CDD\|236561
NZ_CP014955.1\|WP_005083660.1\|303397_303838_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|378454
NZ_CP014955.1\|WP_005083655.1\|304749_305094_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_CP014955.1\|WP_005083651.1\|306424_307027_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014955.1\|WP_012296294.1\|303834_304653_-\|Rv3717-family-N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP014955.1\|WP_005083663.1\|301319_302513_+\|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|173848
NZ_CP014955.1\|WP_005112972.1\|310145_310583_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP014955.1\|WP_005083642.1\|311686_312868_+\|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|173838

Protein	Function_ID	Function_description	E-value
NZ_CP014955.1\|WP_005083669.1\|298324_299599_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	2.12946e-172
NZ_CP014955.1\|WP_005083649.1\|307262_307973_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.42317e-107
NZ_CP014955.1\|WP_005065334.1\|300556_301141_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.03933e-10
NZ_CP014955.1\|WP_005112973.1\|310631_311690_+\|phosphotransferase-family-protein	gnl\|CDD\|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	3.50798e-67
NZ_CP014955.1\|WP_005087054.1\|302526_303348_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	1.97601e-31
NZ_CP014955.1\|WP_005063138.1\|305086_305695_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	3.42747e-112
NZ_CP014955.1\|WP_005115713.1\|313858_315052_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.58938e-64
NZ_CP014955.1\|WP_005063151.1\|315052_315301_-\|30S-ribosomal-protein-S18	gnl\|CDD\|184031	PRK13401, PRK13401, 30S ribosomal protein S18; Provisional.	6.99658e-30
NZ_CP014955.1\|WP_005083648.1\|309313_309898_-\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.00559891
NZ_CP014955.1\|WP_005121857.1\|296886_298257_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.76785e-39
NZ_CP014955.1\|WP_005063148.1\|312903_313887_+\|DEDDh-family-exonuclease	gnl\|CDD\|180377	PRK06063, PRK06063, DEDDh family exonuclease.	0
NZ_CP014955.1\|WP_005072474.1\|307969_309238_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	5.14945e-64
NZ_CP014955.1\|WP_005083666.1\|299595_300570_-\|phosphotransferase	gnl\|CDD\|236561	PRK09550, mtnK, methylthioribose kinase; Reviewed.	2.08002e-12
NZ_CP014955.1\|WP_005083660.1\|303397_303838_+\|SRPBCC-family-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	6.28889e-09
NZ_CP014955.1\|WP_005083655.1\|304749_305094_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	5.06927e-36
NZ_CP014955.1\|WP_012296294.1\|303834_304653_-\|Rv3717-family-N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	5.78698e-39
NZ_CP014955.1\|WP_005083663.1\|301319_302513_+\|acyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|173848	cd01159, NcnH, Naphthocyclinone hydroxylase. Naphthocyclinone is an aromatic polyketide and an antibiotic, which is active against Gram-positive bacteria. Polyketides are secondary metabolites, which have important biological functions such as antitumor, immunosupressive or antibiotic activities. NcnH is a hydroxylase involved in the biosynthesis of naphthocyclinone and possibly other polyketides.	4.66409e-105
NZ_CP014955.1\|WP_005112972.1\|310145_310583_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.41241e-15
NZ_CP014955.1\|WP_005083642.1\|311686_312868_+\|acyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	1.5761e-92

>NZ_CP014955.1|WP_005063138.1|305086_305695_+|recombination-protein-RecR
MFEGPVQDLIDELGKLPGVGPKSAQRIAFHLLGVEAPDIDRLTAALTRVRDGVQFCEVCGNVSDKERCRICADPRRDIALVCVVEEPKDVQAVERTREFRGRYHVLGGALDPLSGVGPDQLRIRELLTRIGTEEDGVSISEVIIATDPNTEGEATATYLVRMLRDFPGLTVTRLASGLPMGGDLEFADELTLGRALSGRRPL
>NZ_CP014955.1|WP_005083655.1|304749_305094_+|YbaB/EbfC-family-nucleoid-associated-protein
MQPGGAPDMSALLAQAQQMQQQLMAAQAQIAAAEVTGESGGGLVRITGKGSGEVTSVQIDPKIVDPEDVETLQDLIIGALADLTSKTQELASQRLGPLAGGLGDLGGGLGLPGV
>NZ_CP014955.1|WP_012296294.1|303834_304653_-|Rv3717-family-N-acetylmuramoyl-L-alanine-amidase
MRVSFWRAAGLAGTALLTAASVTVLPVATPSAPTTFTAGAAPGIAGRIVVLDPGHNGANDSSINNQVPDGRGGTKSCQTSGTATDGGYPEHTFTWNTVLLIRQQLTQLGVRTAMTRGDDNKLGPCIDKRAEIENSYNPDAVVSIHADGGPAGGHGFHVNYSNPPVNAVQGEPTLRFAKTMRDSLQAAGLTPATYIGTGGLYGRSDLAGLNLAQHPKVLVELGNMKNAQDSAMMTSPEGRSKYAQAVVQGIVAYLSGTAPAAAPAPEAAPAGG
>NZ_CP014955.1|WP_005083660.1|303397_303838_+|SRPBCC-family-protein
MGQVSASSSVLIDAAPEAVLAAVADYQNVRPQILSSHYRDYQVLEGGQGEGTVASWKLQATESRVRDIKSAVSVAGHTVIEKDANSTLVTTWTVAPAGPGSSVTTKTAWTGGGGIKGFFEKTFAPLGLKKIQAEVLANLKQVVEKG
>NZ_CP014955.1|WP_005087054.1|302526_303348_+|enoyl-CoA-hydratase/isomerase-family-protein
MNAGIPELTGLRCALDDRVLTVLFDHGQLNLLDGPLMSSLSRLARWLSGSDDVTVVLFGSANPDFFIAHLNVEILQSATARTAESVASFQRLVGRFRALRQATIALVEGRVAGGGSEFLLNLDMRFAVRGKALFNQVETGLGIVPAGSGPQHLVQGMGRARALEVILGHEDFGADLAERYGWVNRALNPDEGWRFVNRLARRIAANPLDLIAGVKNTVDALASDLEPGLAAERAAIVAAFADEHSARRIAHFLQRGGQTVEGERRLGDLVSEP
>NZ_CP014955.1|WP_005083663.1|301319_302513_+|acyl-CoA-dehydrogenase-family-protein
MTSSTAVQPDAVQRARELAPAIAARALEAERLRRMPDETIAELSRSGLFSLMAPRRYGGDEASLETLVGAVIEVGKVCGSTAWTFCIYGIHNWLAGLFPEQLQDEMFGSVPAGSPLLFPGSWSPSGIATPVEGGYKITGRWQFGSGVWHSSWASVAAVVQHEEPPKYPDLRTFMIPRSDLEVIDTWFTSGLRGTGSMDIAVNDVFVPEHRVQEFGPLARGQSPSAELHGSAIYRIPLFCALSNVAAAPAVGMALGTVELFTEKIKTRVMRYSMQEQSKLATAHRRMGHVAAQAESARTLLLQTVRDVEDKLRSGEGLTTGDRVAVRRNCAYIVEVCKQAIGEAVEACGASAQYEDSPLQRHLRDVNTLSTHVVYDTDSAYELYGRVELGLPPGSVAF
>NZ_CP014955.1|WP_005065334.1|300556_301141_-|TetR/AcrR-family-transcriptional-regulator
MDAARVVISRVGYAETRVIDITTEAGKSVGVFYNYFTDKAELLRTMVDEFRDDAYARGDTVATSDRPPHEVIRDIVTVYWTTYREHAPVLSGVFQAAQVDPTFVDYWRNLRAPARTMIANNIRHLQARGYCPGMDPDITASAIGAMLDYFCYVWLVEGGERGRSAVTDEEAIDTLARIWFNALWWKSEGAHGAT
>NZ_CP014955.1|WP_005083666.1|299595_300570_-|phosphotransferase
MALPDWVVTLLSRAGLTPVQAQPLTGGVSSEVWRVRLSSGESVVVKRAVERLRVQAQWVVPLERNTFEARYLAAAATIVPAFAPQIVVADDDLHAFAMTDLGPIPSWRDDLAAGRVDADVGAVLGDRLAAIHAQTAGNDSTAREFASDHLFEALRIEPYLRYSAVRSPAHAAALSELAHDLADTHIALVHGDVSPKNIIVTRDGPVLTDAECAWYGDPAFDLAFCLNHLLLKRIWKPQHRALLQETSTRLLTAYLRGVSWEPPDAVAARIARLLPALALARIDGRSPVDYLSTAQRESLRTRAGRALHESATDPLAVAQQLEGL
>NZ_CP014955.1|WP_005083669.1|298324_299599_-|phosphopyruvate-hydratase
MTGTRISRVHARRVWDSRGRPTIEAELLLSDGSTGRAIAPAGASRGSGEVTDLRDGGGPFAGYDVTAAVAAARGLAHHLVDVDAANQQAVDAALTAADQSAEFAAIGGNTAVAMSMAAAHAAAASHGIPLWRYLIGDKPAAMPLPEIQVIGGGAHAARRTDVQDFMVVPAAANTIEEGLNWLAEIHRACGAILSDRGRLAGVADEGGWWPMVDSNEDALELLVASIERAGLQPGTQATIALDIASTEFGSGGRYRLGLDGTELDSDAWSEVLIGWIDKYPIASIEDPLAEDDPAALAAFTQAVGHRVLVVGDDFTVTDAGRVRRATESGACNGLLVKPNQAGTLSAAKTAHDTAHDCGWDTIVSARSGESEDVTIAHLAVGWGAEQLKVGSITRSERTAKWNELLRIDEQLGGAPIRLGRLSLG
>NZ_CP014955.1|WP_005121857.1|296886_298257_-|FAD-binding-oxidoreductase
MPIASGSAHAEGVNRLLRSYRAIPTTATVRLAKPTSNLFRARAKPTTPGLDTSGLTGVIDVDPVNRTAEVAGMCTYEDLVAATLAHGLSPLVVPQLKTITLGGAVTGLGIESASFRNGLPHESVLEMDILTGSGEIVTAAPDRLADLYRGFPNSYGTLGYSVRLRIQLEPVKPFVALRHIRFHSLEELVSVMESIVNTAAYEGESVDYLDGVVFAADECYLSLGALTAAPGPVSDYTGQRVYYRSIQHPDGISNDRLTIHDYLWRWDTDWFWCSRAFGAQNPGIRRLWPRKYRRSSVYWKLIALDQRYDIADRIERFNGRPARERVVQDVEVPISRTPEFLRWFLDEIPIEPVWVCPLRLRDSEGWPLYPIRPGQTYVNIGFWSSVPAGAVEGATNRLIERKVSELGGHKSLYSESFYTRDEFEPLYGGEHYQTLKKTYDPDNRLLDLYAKAVRRQ
>NZ_CP014955.1|WP_005083651.1|306424_307027_-|hypothetical-protein
MIVEPGDREWAGVTHRLEITGFDDLQALRLVPERLEERVARQAIAADDTEAREIARRIAETGDRHADAEDSCCAPCASKNDSRASYPVRLGRLYREIRPAMHTNLSRAVGDALGVPLTADSLQAKITHSFTQRFAVHVTRIPLVIVLFKDIEIGKNATLTLSSKAKSLWANDIRIHSGGRLVITSGYIKIRAASVRGNLA
>NZ_CP014955.1|WP_005083649.1|307262_307973_-|type-1-glutamine-amidotransferase
MSESTVRVGLVLPDVMGTYGDSGNAVVLRQRLRMRGIDAEIVETTLADPVPDSLDVYTLGGAEDYAQRLATRHLIAHPGLQRAAERGAPVLAICAAIQVLGHWYETSSGERVEGVGLLDVTTSPQHQRTIGELAGVPIMDELEDTLTGFENHRGGTVLGPAATPLSRVSRGAGNRTGDGSDGVVQGSVIATYMHGPCLARNPELADLLLARAMNVPELTPLDLDEVARLRRERLKS
>NZ_CP014955.1|WP_005072474.1|307969_309238_-|Mur-ligase-family-protein
MPIEHLSPRGRIALAAGSAARWASRISGRGAGSMIGGLIALKLDGSVLAQLGRGRRTVLITGTNGKSTTTRMTAAALATVGPVATNTEGSNMDAGLVAALAGTREADVAVLEVDEMHVPHVADAVNPAVIVLLNLSRDQLDRVGEINNIERTLRKGLARHRDAVIVANCDDVLMASAAYDSPHVVWVAAGGGWAGDSVSCPRSGELIMRDGNRWYSTGTDFARPDPDWWFDDDRIYGPSGISLPMSLTLPGTANRGNATLAVAAAVELGARPGPAVDAVSAVDQVAGRYRSINLGDHTIRLLLAKNPAGWQEALSMVDTDADGLVIAVNGQVPDGEDLSWLWDVNFEHFACDNGESPVPPVVAAGERGTDLAVRLTYASVTHTLQHDPVQAIKACPPGRVDVIANYTAFLNLNRALAKGGAA
>NZ_CP014955.1|WP_005083648.1|309313_309898_-|hypothetical-protein
MSGSFAGFEGPGSGFGAFSGAGFGGPGFGGPGFGGPGLGPGGPAGFGLRIKRAVTASLLLDGPASAAQIVQRVSDATEDEILLPEPVVERVLERLAHKGVVTTEDGVATLTDFGRKVLAKRGITSQTAQALRAKVFPKLVNVLKLRSGLAEIAGLARVIAITGTDEQKEKLAEAGATLLATVNDVKRSLQSAVA
>NZ_CP014955.1|WP_005112972.1|310145_310583_+|MarR-family-transcriptional-regulator
MSESDEIEPLGYLMFRAGAVMRPRVLAVLRPLGLGMPEFMCLRMLNENPGRTSAELARENNVSAQAMNQVLNGLQNISLVSRPAVPASGRALPAKVTAKGKALLKRVESAIWAAEDEMFSRLGVDDQRELRRILGRLIDAASENE
>NZ_CP014955.1|WP_005112973.1|310631_311690_+|phosphotransferase-family-protein
MSQSTGQFRAHHQSTSQDWAALSAWVARQGHTLETSGARQFAGGKANLNYLVVLDGQPAVFRRPPAGPIAEGANDMAREWRVLSRLGDGFALAPRGLLYCDDLDVLAAPFQFLEYREGLAIGGELPAGLPVDAPSRITATLIEAMTALHRVSPERVGLGELGRPEGLLERQLTGWTRRAHVVWPDGLPDVVTYLTSRLAEEIPEPSAISLLHMDLKLDNMLIDQETLSPNAIIDWDMATRGCPLFDLAILVSYWMEPDDPAGVRAVNQMPTTAQGFGKRADVIDSYFAAAGMPPRPLHWHVACARLRLAVAWMQLYRKWQSGDLIGPGYADFENIAMSVLDWATTQFTEGEI
>NZ_CP014955.1|WP_005083642.1|311686_312868_+|acyl-CoA-dehydrogenase-family-protein
MIDFSIPEELAAKAQRVREFVTETVIPYERDPRLTAHGPTEELRDELVGKARAAGLLTVQAPESYGGWGLSHIGQAVIFEAAGWSTLGPIAMNCAAPDEGNMFLLGKITNEEQSEKFLRPVIEGYQRSAFAMTEPDGAGSDPSQLKTSATFDGQNFVINGRKWLITGARGAKTWIIMANLEANDHLPEGPTLFLCDGETEGIVIERIMNTMDRNYAEGHAVVRFDNLTLPREALLGETGQAFRYAQLRLAPARLTHCMRWLGAASRAQDIAVDYARTRTSFGKTIGEHQGVSFMLADNEIALHQCRLTIWHACWMMDNGAKGRHESSMAKSFVSEELFKVTDRCVQVLGGIGISDETPVEMIFRDMRAFRLYDGPTEVHKYAIGRQVLRTPRA
>NZ_CP014955.1|WP_005063148.1|312903_313887_+|DEDDh-family-exonuclease
MPIWGQTPDHSPKWVVVDLETSGFQPGRARVISVAALAMDADGTITDSVVSLLNPGVDPGPTHVHGLTPEMLEGQPEFSDIAPDLIALLRGRTLVAHNVGFDYSFLAAEAELVGAELPTEAVMCTVELTRRLELDTPNLRLETLAAHWGVEQLKAHDAYDDARVLAEVLPKVLERARERGTWLPIRETTRKRWPNGRVTHDELRPLKTLASRQPCHWLNPGPYTAGQPLVQGMRVALSSEVSRTHEELIEQIMQAGLAYADAVDEDTSLVICNQENPEQGKGFHARSLGVPLLDDRTFMTEVRRVVGGTDIEQFTVPSRAGAQYSLF
>NZ_CP014955.1|WP_005115713.1|313858_315052_+|serine-hydrolase
MPELSTRCFDESSLMRRILAVVLTIALLVSACGKHSAIVVAELDPQTTAKLDSAINEILTSAAVPGAIVGVWGPKGQYVRTFGVANTATRAPLRPDFYHRIGSVTKTFTVTAVLQLVDEGKVELDDPIAKYVDKVPNGNKITLRELARMQSGLFNYSMSLAFSRDLEADPRRQYSTHELLDYAFAQPSNFVPGQGYEYSNTNAVLLGQVVEKVSGQTLPAFVQEHITGPLGMRRTSFPETSAIADPHARGYTQLTPTGSLVDSTDWNPSWASWAGAMISTLDDLRIWVPALATGVLLKPDSQQQRLQTVAMPPVPDDIRYGLGIFDARGWIGHSGSIPGYQTLAIYSPAEQTTVVALLNTDVAKQPAQPSTLFGTAITKVISPDHVFLLENAIPQPR
>NZ_CP014955.1|WP_005063151.1|315052_315301_-|30S-ribosomal-protein-S18
MAPKTPRNRRAKLVDTKPAKPNLFAKLGVSSVDYKDTNTLRMFLSERGKIRSRRVTGLTVQQQRQVANAIKNAREMALLPYA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	MF140397	Arthrobacter phage Abidatro, complete genome	37516-37542	4	0.852
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	580722-580748	4	0.852
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	580390-580416	4	0.852
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	1428875-1428901	4	0.852
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	903089-903115	4	0.852
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	1428853-1428879	4	0.852
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	137845-137871	4	0.852
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NZ_CP021796	Sinorhizobium meliloti strain USDA1157 plasmid accessoryA, complete sequence	106941-106967	4	0.852
NZ_CP014955_1	1.3\|306057\|27\|NZ_CP014955\|CRT	306057-306083	27	NZ_LT703507	Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 3	66353-66379	6	0.778
NZ_CP014955_1	1.3\|306057\|27\|NZ_CP014955\|CRT	306057-306083	27	NZ_CP015273	Mycobacterium chimaera strain ZUERICH-1 plasmid unnamed 1, complete sequence	58577-58603	6	0.778
NZ_CP014955_1	1.3\|306057\|27\|NZ_CP014955\|CRT	306057-306083	27	NZ_CP029333	Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence	107327-107353	6	0.778
NZ_CP014955_1	1.3\|306057\|27\|NZ_CP014955\|CRT	306057-306083	27	NZ_CP045964	Mycobacterium chimaera strain AUSMDU00007395 plasmid pAUSMDU00007395_01, complete sequence	49820-49846	6	0.778
NZ_CP014955_1	1.3\|306057\|27\|NZ_CP014955\|CRT	306057-306083	27	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	50360-50386	6	0.778
NZ_CP014955_1	1.3\|306057\|27\|NZ_CP014955\|CRT	306057-306083	27	NZ_CP015280	Mycobacterium chimaera strain DSM 44623 plasmid unnamed 2, complete sequence	41759-41785	6	0.778
NZ_CP014955_1	1.3\|306057\|27\|NZ_CP014955\|CRT	306057-306083	27	NZ_CP023153	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_2, complete sequence	29396-29422	6	0.778
NZ_CP014955_1	1.3\|306057\|27\|NZ_CP014955\|CRT	306057-306083	27	NZ_CP019224	Mycobacterium chimaera strain CDC 2015-22-71 plasmid pDHQP20152271_1, complete sequence	74501-74527	6	0.778
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NC_012853	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132503, complete sequence	120961-120987	6	0.778
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NZ_CP024587	Roseomonas sp. FDAARGOS_362 plasmid unnamed3, complete sequence	83823-83849	6	0.778
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	444070-444096	6	0.778
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	47017-47043	6	0.778
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	KT224359	Bacillus phage TsarBomba, complete genome	51748-51774	6	0.778
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NC_015147	Pseudarthrobacter phenanthrenivorans Sphe3 plasmid pASPHE302, complete sequence	87623-87649	6	0.778
NZ_CP014955_1	1.4\|306102\|27\|NZ_CP014955\|CRT	306102-306128	27	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	338995-339021	6	0.778

1. spacer 1.4|306102|27|NZ_CP014955|CRT matches to MF140397 (Arthrobacter phage Abidatro, complete genome) position: , mismatch: 4, identity: 0.852

gcctccggttccgcctgctcctccgtg	CRISPR spacer
gccgccggttccgcccgctcctccggc	Protospacer
*** ***********.*********

2. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 4, identity: 0.852

gcctccggttccgcctgctcctccgtg	CRISPR spacer
ggctccggctccggctgctcctccgtc	Protospacer
* ******.**** ************

3. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 4, identity: 0.852

gcctccggttccgcctgctcctccgtg	CRISPR spacer
ggctccggctccggctgctcctccgtc	Protospacer
* ******.**** ************

4. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 4, identity: 0.852

gcctccggttccgcctgctcctccgtg	CRISPR spacer
gccgacggttccgcctgctcctccttt	Protospacer
***  ******************* *

5. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 4, identity: 0.852

gcctccggttccgcctgctcctccgtg	CRISPR spacer
ggctccggctccggctgctcctccgtc	Protospacer
* ******.**** ************

6. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 4, identity: 0.852

gcctccggttccgcctgctcctccgtg	CRISPR spacer
gccgacggttccgcctgctcctccttt	Protospacer
***  ******************* *

7. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 4, identity: 0.852

gcctccggttccgcctgctcctccgtg	CRISPR spacer
ggctccggctccggctgctcctccgtc	Protospacer
* ******.**** ************

8. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NZ_CP021796 (Sinorhizobium meliloti strain USDA1157 plasmid accessoryA, complete sequence) position: , mismatch: 4, identity: 0.852

gcctccggttccgcctgctcctccgtg	CRISPR spacer
ggctccggctccggctgctcctccgtc	Protospacer
* ******.**** ************

9. spacer 1.3|306057|27|NZ_CP014955|CRT matches to NZ_LT703507 (Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 3) position: , mismatch: 6, identity: 0.778

tctgccgaattcgcagtcgtccccgtc	CRISPR spacer
ggggccgaattcgcggtcgtgcccgtg	Protospacer
   ***********.***** *****

10. spacer 1.3|306057|27|NZ_CP014955|CRT matches to NZ_CP015273 (Mycobacterium chimaera strain ZUERICH-1 plasmid unnamed 1, complete sequence) position: , mismatch: 6, identity: 0.778

tctgccgaattcgcagtcgtccccgtc	CRISPR spacer
ggggccgaattcgcggtcgtgcccgtg	Protospacer
   ***********.***** *****

11. spacer 1.3|306057|27|NZ_CP014955|CRT matches to NZ_CP029333 (Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence) position: , mismatch: 6, identity: 0.778

tctgccgaattcgcagtcgtccccgtc	CRISPR spacer
ggggccgaattcgcggtcgtgcccgtg	Protospacer
   ***********.***** *****

12. spacer 1.3|306057|27|NZ_CP014955|CRT matches to NZ_CP045964 (Mycobacterium chimaera strain AUSMDU00007395 plasmid pAUSMDU00007395_01, complete sequence) position: , mismatch: 6, identity: 0.778

tctgccgaattcgcagtcgtccccgtc	CRISPR spacer
ggggccgaattcgcggtcgtgcccgtg	Protospacer
   ***********.***** *****

13. spacer 1.3|306057|27|NZ_CP014955|CRT matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 6, identity: 0.778

tctgccgaattcgcagtcgtccccgtc	CRISPR spacer
ggggccgaattcgcggtcgtgcccgtg	Protospacer
   ***********.***** *****

14. spacer 1.3|306057|27|NZ_CP014955|CRT matches to NZ_CP015280 (Mycobacterium chimaera strain DSM 44623 plasmid unnamed 2, complete sequence) position: , mismatch: 6, identity: 0.778

tctgccgaattcgcagtcgtccccgtc	CRISPR spacer
ggggccgaattcgcggtcgtgcccgtg	Protospacer
   ***********.***** *****

15. spacer 1.3|306057|27|NZ_CP014955|CRT matches to NZ_CP023153 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_2, complete sequence) position: , mismatch: 6, identity: 0.778

tctgccgaattcgcagtcgtccccgtc	CRISPR spacer
ggggccgaattcgcggtcgtgcccgtg	Protospacer
   ***********.***** *****

16. spacer 1.3|306057|27|NZ_CP014955|CRT matches to NZ_CP019224 (Mycobacterium chimaera strain CDC 2015-22-71 plasmid pDHQP20152271_1, complete sequence) position: , mismatch: 6, identity: 0.778

tctgccgaattcgcagtcgtccccgtc	CRISPR spacer
ggggccgaattcgcggtcgtgcccgtg	Protospacer
   ***********.***** *****

17. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NC_012853 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132503, complete sequence) position: , mismatch: 6, identity: 0.778

gcctccggttccgcctgctcctccgtg	CRISPR spacer
aaggccggttccgcctgctcatccgtt	Protospacer
.   **************** *****

18. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NZ_CP024587 (Roseomonas sp. FDAARGOS_362 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.778

gcctccggttccgcctgctcctccgtg	CRISPR spacer
cgatccggttccgcctgctcctgcctc	Protospacer
   ******************* * *

19. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 6, identity: 0.778

gcctccggttccgcctgctcctccgtg	CRISPR spacer
gctaccggttccgcctgctcctcgagc	Protospacer
**. ******************* .

20. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.778

gcctccggttccgcctgctcctccgtg	CRISPR spacer
tggaccggttccgcctggacctccgtg	Protospacer
    *************  ********

21. spacer 1.4|306102|27|NZ_CP014955|CRT matches to KT224359 (Bacillus phage TsarBomba, complete genome) position: , mismatch: 6, identity: 0.778

gcctccggttccgcctgctcctccgtg	CRISPR spacer
tgctacgtttccgcctgctcctccgcc	Protospacer
  ** ** *****************.

22. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NC_015147 (Pseudarthrobacter phenanthrenivorans Sphe3 plasmid pASPHE302, complete sequence) position: , mismatch: 6, identity: 0.778

gcctccggttccgcctgctcctccgtg	CRISPR spacer
cggacctgtcccgcctgctcctccgtg	Protospacer
    ** **.*****************

23. spacer 1.4|306102|27|NZ_CP014955|CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.778

gcctccggttccgcctgctcctccgtg	CRISPR spacer
tggaccggttccgcctggacctccgtg	Protospacer
    *************  ********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1737739 : 1745512

Mycobacterium_phage(44.44%)

integrase

attL 1730192:1730205|attR 1741761:1741774

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1730192:1730205	attL	NA	NA	NA	NA
WP_005110228.1\|1737739_1738990_+\|integrase	site-specific integrase	G8IR34	Mycobacterium_virus	1.6e-93	47.0
WP_005110229.1\|1738986_1739757_-	DUF732 domain-containing protein	NA	NA	NA	NA
WP_005110231.1\|1740163_1741186_-	acyltransferase	A9YX16	Burkholderia_phage	5.7e-25	29.1
WP_005115843.1\|1741404_1742133_+	hypothetical protein	A0A068F4L5	Mycobacterium_phage	4.7e-58	50.6
1741761:1741774	attR	NA	NA	NA	NA
WP_012296456.1\|1742113_1742500_-	helix-turn-helix domain-containing protein	A0A1W6JTN0	Mycobacterium_phage	3.9e-35	72.7
WP_012296457.1\|1742666_1742987_+	helix-turn-helix transcriptional regulator	A0A1W6JTT8	Mycobacterium_phage	2.5e-35	73.8
WP_005110236.1\|1743045_1743852_+	phage regulatory protein/antirepressor Ant	W6AT80	Mycobacterium_phage	1.0e-93	69.8
WP_005110238.1\|1743851_1744187_+	hypothetical protein	A0A142K9K4	Gordonia_phage	8.1e-13	41.7
WP_005115845.1\|1744186_1744579_+	hypothetical protein	A0A142K9K5	Gordonia_phage	1.8e-11	45.0
WP_005110240.1\|1744822_1745512_+	helix-turn-helix transcriptional regulator	A0A2D1GGB6	Gordonia_phage	1.5e-05	36.7

DBSCAN-SWA_2

1749595 : 1799777

Mycobacterium_phage(78.57%)

integrase,terminase,portal,tail,transposase

attL 1796916:1796933|attR 1805517:1805534

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005110252.1\|1749595_1750234_+	ERF family protein	A0A1B0XTM7	Freshwater_phage	9.0e-45	64.3
WP_012296462.1\|1750226_1750652_+	HNH endonuclease	NA	NA	NA	NA
WP_005110255.1\|1750651_1751065_+	hypothetical protein	NA	NA	NA	NA
WP_005110256.1\|1751210_1751471_+	hypothetical protein	NA	NA	NA	NA
WP_005110257.1\|1751467_1752571_+	hypothetical protein	A0A1B1IP91	uncultured_Mediterranean_phage	1.5e-26	28.8
WP_012296463.1\|1752601_1752856_+	hypothetical protein	NA	NA	NA	NA
WP_005110260.1\|1752856_1753792_+	hypothetical protein	A0A023ZWF6	Mycobacterium_phage	6.1e-26	44.6
WP_005110262.1\|1753926_1754076_+	hypothetical protein	NA	NA	NA	NA
WP_012296464.1\|1754413_1754596_+	hypothetical protein	NA	NA	NA	NA
WP_005110265.1\|1754728_1755034_+	hypothetical protein	NA	NA	NA	NA
WP_012296465.1\|1755030_1755327_+	hypothetical protein	A0A222ZKN0	Mycobacterium_phage	7.4e-10	45.1
WP_005110268.1\|1755323_1755641_+	hypothetical protein	A0A1P8DUA9	Mycobacterium_phage	6.3e-07	34.5
WP_005110270.1\|1755945_1756263_+	WhiB family transcriptional regulator	A0A2P1JRB7	Mycobacterium_phage	3.2e-11	45.5
WP_021269284.1\|1756262_1756577_+	WhiB family transcriptional regulator	A0A1B0XUI6	Freshwater_phage	6.8e-14	50.0
WP_005110271.1\|1756615_1757047_+	hypothetical protein	O34053	Streptococcus_phage	3.1e-17	43.0
WP_012296466.1\|1757061_1757355_+	hypothetical protein	NA	NA	NA	NA
WP_005131124.1\|1757323_1757692_+	DUF4326 domain-containing protein	A0A142KC74	Gordonia_phage	8.5e-32	58.8
WP_005110272.1\|1757831_1758509_+	hypothetical protein	M4WA13	Mycobacterium_phage	8.8e-67	54.5
WP_005110273.1\|1758505_1758706_+	hypothetical protein	NA	NA	NA	NA
WP_012296467.1\|1759589_1759922_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_005110276.1\|1759918_1760170_+	XRE family transcriptional regulator	A0A2D1GR59	Pseudomonas_phage	7.1e-14	48.1
WP_005110277.1\|1760441_1760666_+	hypothetical protein	NA	NA	NA	NA
WP_005110280.1\|1760882_1761179_+	hypothetical protein	NA	NA	NA	NA
WP_005110281.1\|1761217_1761394_+	hypothetical protein	NA	NA	NA	NA
WP_005110282.1\|1761541_1761787_+	hypothetical protein	NA	NA	NA	NA
WP_012296468.1\|1761825_1762062_+	hypothetical protein	A0A088FBL5	Mycobacterium_phage	2.6e-05	92.3
WP_005115852.1\|1762058_1762334_+	hypothetical protein	NA	NA	NA	NA
WP_005110285.1\|1762373_1762646_+	hypothetical protein	NA	NA	NA	NA
WP_012296469.1\|1762684_1762852_+	hypothetical protein	NA	NA	NA	NA
WP_005110289.1\|1763126_1763408_-	DUF732 domain-containing protein	NA	NA	NA	NA
WP_005110290.1\|1763537_1764800_+	glycosyltransferase	G8I6V8	Mycobacterium_virus	8.4e-71	73.1
WP_005110291.1\|1764806_1765628_+	hypothetical protein	A0A2D1GAR3	Mycobacterium_phage	4.8e-83	55.4
WP_012296470.1\|1765636_1766320_+	hypothetical protein	A0A0A1ENE4	Mycobacterium_phage	9.2e-88	71.7
WP_005110294.1\|1766319_1766565_+	hypothetical protein	NA	NA	NA	NA
WP_005110295.1\|1766564_1766981_+	hypothetical protein	A0A068F2M6	Mycobacterium_phage	6.3e-23	50.4
WP_005110296.1\|1767055_1767424_+	hypothetical protein	NA	NA	NA	NA
WP_005110298.1\|1767423_1767642_+	hypothetical protein	NA	NA	NA	NA
WP_012296471.1\|1767638_1767842_+	hypothetical protein	NA	NA	NA	NA
WP_012296472.1\|1767838_1768471_+	hypothetical protein	A0A2P1JRF0	Mycobacterium_phage	5.7e-52	48.5
WP_005110299.1\|1768612_1768897_+	hypothetical protein	NA	NA	NA	NA
WP_032689852.1\|1768880_1769228_+	HNH endonuclease	G1BSJ4	Mycobacterium_virus	1.3e-05	42.4
WP_005114206.1\|1769357_1769816_+	hypothetical protein	A0A0A0RSN6	Mycobacterium_phage	5.2e-55	70.2
WP_005110302.1\|1769823_1771476_+\|terminase	large terminase	A0A0S1S0L0	Mycobacterium_phage	1.2e-250	74.1
WP_005110303.1\|1771494_1772859_+\|portal	phage portal protein	A0A1C9LZY2	Mycobacterium_phage	2.1e-168	66.1
WP_005110304.1\|1772909_1773524_+	hypothetical protein	A0A088FVU5	Mycobacterium_phage	1.1e-28	47.6
WP_005110305.1\|1773545_1774376_+	hypothetical protein	A0A0A0RSP1	Mycobacterium_phage	7.7e-81	59.8
WP_005110306.1\|1774375_1774948_+	hypothetical protein	A0A1C9M013	Mycobacterium_phage	1.1e-41	51.1
WP_012296473.1\|1774944_1775280_+	hypothetical protein	G8I4C3	Mycobacterium_phage	2.3e-15	39.3
WP_005110308.1\|1775279_1775546_+	hypothetical protein	A0A068F3C1	Mycobacterium_phage	1.5e-14	50.0
WP_005110309.1\|1775545_1775923_+	hypothetical protein	NA	NA	NA	NA
WP_005110310.1\|1775989_1776577_+	hypothetical protein	A0A068F8K4	Mycobacterium_phage	1.6e-69	67.2
WP_005110311.1\|1776671_1776938_+	hypothetical protein	A0A068F4G7	Mycobacterium_phage	1.3e-13	50.7
WP_005067420.1\|1777054_1777366_+	hypothetical protein	A0A068F4G7	Mycobacterium_phage	4.0e-14	43.7
WP_005110312.1\|1777376_1781390_+\|tail	phage tail tape measure protein	A0A068F1L4	Mycobacterium_phage	4.0e-284	58.0
WP_005110313.1\|1781393_1782503_+	hypothetical protein	A0A068F3C3	Mycobacterium_phage	1.3e-155	67.9
WP_005110314.1\|1782505_1784302_+	hypothetical protein	A0A068F4H3	Mycobacterium_phage	2.4e-236	63.2
WP_005115854.1\|1784316_1784835_+	hypothetical protein	A0A068F2D2	Mycobacterium_phage	6.2e-36	49.1
WP_005110315.1\|1784827_1785913_+\|tail	tail protein	A0A068F8L3	Mycobacterium_phage	1.4e-151	67.8
WP_005110317.1\|1785912_1790037_+	serine hydrolase	A0A0K1LLJ4	Mycobacterium_phage	2.0e-153	40.8
WP_005115856.1\|1790048_1790447_+	hypothetical protein	A0A0U1UNR7	Pseudomonas_phage	2.8e-28	48.9
WP_012296474.1\|1790449_1791847_+	hypothetical protein	G3MDN1	Mycobacterium_phage	1.2e-30	45.3
WP_005067432.1\|1791862_1792294_+	hypothetical protein	A0A2P1JR64	Mycobacterium_phage	2.1e-58	80.4
WP_005110323.1\|1792556_1793930_+	chitinase	A0A222ZPL1	Mycobacterium_phage	2.3e-122	52.4
WP_005110325.1\|1793926_1794343_+	hypothetical protein	A0A2D2W368	Mycobacterium_phage	3.5e-05	35.3
WP_005110326.1\|1794393_1795308_+	hypothetical protein	A0A2P1CCW0	Mycobacterium_phage	8.0e-55	44.8
WP_005110328.1\|1795356_1795578_+	hypothetical protein	NA	NA	NA	NA
WP_012296475.1\|1795574_1796771_+	hypothetical protein	S5W0N6	Mycobacterium_phage	1.8e-118	56.7
1796916:1796933	attL	NA	NA	NA	NA
WP_079454429.1\|1797060_1797708_+\|transposase	TnsA-like heteromeric transposase endonuclease subunit	NA	NA	NA	NA
WP_005093426.1\|1797704_1799777_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
1805517:1805534	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2933482 : 2942041

Streptococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005068898.1\|2933482_2934154_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	4.9e-17	31.1
WP_005093596.1\|2934267_2935191_+	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	1.1e-08	31.6
WP_005091054.1\|2935192_2936062_+	class A beta-lactamase	A0A1B0VBP7	Salmonella_phage	5.8e-55	45.6
WP_005068903.1\|2936163_2938530_-	RelA/SpoT family protein	A0A291L9W9	Bordetella_phage	1.8e-13	38.4
WP_005082386.1\|2938560_2939094_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	8.1e-15	36.4
WP_005093597.1\|2939090_2940767_-	hypothetical protein	NA	NA	NA	NA
WP_005090079.1\|2940766_2942041_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.5e-22	28.6

DBSCAN-SWA_4

4172949 : 4182441

Burkholderia_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005112210.1\|4172949_4174074_-	acyltransferase	A9YX16	Burkholderia_phage	2.3e-19	28.4
WP_005085927.1\|4174070_4175339_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	3.3e-06	40.3
WP_012296730.1\|4175388_4176195_-	class I SAM-dependent methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	4.9e-56	52.6
WP_005085925.1\|4176405_4177098_-	class I SAM-dependent methyltransferase	Q98VI8	Paramecium_bursaria_Chlorella_virus	3.7e-12	30.2
WP_005112211.1\|4177330_4178461_-	acyltransferase	A9YX16	Burkholderia_phage	4.1e-16	27.6
WP_005085923.1\|4178628_4179690_-	NAD-dependent epimerase/dehydratase family protein	A0A0E3IB24	Synechococcus_phage	4.1e-18	26.1
WP_005094865.1\|4179852_4181112_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	1.6e-05	39.2
WP_005062166.1\|4181574_4182441_+	glucose-1-phosphate thymidylyltransferase RfbA	H9NC64	Sphingomonas_phage	2.8e-89	57.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage