CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014961	Mycobacteroides abscessus strain FLAC054 chromosome, complete genome	4 crisprs	DEDDh,cas3,csa3,DinG,cas4,WYL	1	2	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014961_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014961_1

709367-709516

Orphan

Consensus_repeat	Method
CCACCTCAGGGGTGGGCTCCGAGCGGGCCGGCTCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014961_1

>merge|NZ_CP014961|1|709367-709516|CRISPRCasFinder
CCACCTCAGGGGTGGGCTCCGAGCGGGCCGGCTCAGGGGTGGGGTCCTGATGGTCCTCCACCTCAGGGGTGGGCTCCGAGCGGGCCGGCTCAGGGGTGGGGTCCTGATGGTCCTCCACCTCAGGGGTGGGCTCCGAGCGGGCCACCTCAG

>NZ_CP014961|1|1|709367-709516|CRISPRCasFinder
CCACCTCAGGGGTGGGCTCCGAGCGGGCCGGCTCAG	GGGTGGGGTCCTGATGGTCCTCCACCTCAGGGGTGGGCTCCGAGCGGGCCGGCTCAGGGGTGGGGTCCTGATGGTCCT
CCACCTCAGGGGTGGGCTCCGAGCGGGCCACCTCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014961.1\|WP_005085539.1\|721892_723392_+\|type-VII-secretion-integral-membrane-protein-EccD	unknown	unknown	gnl\|CDD\|274855
NZ_CP014961.1\|WP_005085526.1\|706467_706794_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_131804371.1\|704144_705587_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235906
NZ_CP014961.1\|WP_131726083.1\|701329_701866_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_079493757.1\|699211_700429_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373961
NZ_CP014961.1\|WP_005085524.1\|705643_705979_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_005085540.1\|723388_724885_-\|type-VII-secretion-protein-EccB	unknown	unknown	gnl\|CDD\|368288
NZ_CP014961.1\|WP_131726082.1\|700425_700785_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_100247137.1\|714847_716230_-\|type-VII-secretion-associated-serine-protease-mycosin	unknown	unknown	gnl\|CDD\|274856
NZ_CP014961.1\|WP_032701720.1\|712582_714325_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223531
NZ_CP014961.1\|WP_005085537.1\|716265_717768_-\|type-VII-secretion-integral-membrane-protein-EccD	unknown	unknown	gnl\|CDD\|274855
NZ_CP014961.1\|WP_005085517.1\|700796_701333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_032701723.1\|725114_726725_+\|type-VII-secretion-protein-EccE	unknown	unknown	gnl\|CDD\|274857
NZ_CP014961.1\|WP_005085520.1\|701862_703347_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_005085525.1\|706090_706471_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_005085521.1\|703368_704127_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379414
NZ_CP014961.1\|WP_005064840.1\|726748_727075_-\|monovalent-cation/H(+)-antiporter-subunit-G	unknown	unknown	gnl\|CDD\|237169
NZ_CP014961.1\|WP_005085538.1\|717764_721742_-\|type-VII-secretion-protein-EccCa	unknown	unknown	gnl\|CDD\|274858
NZ_CP014961.1\|WP_005064841.1\|727071_727365_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181179
NZ_CP014961.1\|WP_005085533.1\|710761_712576_+\|type-VII-secretion-AAA-ATPase-EccA	unknown	unknown	gnl\|CDD\|188437

Protein	Function_ID	Function_description	E-value
NZ_CP014961.1\|WP_005085533.1\|710761_712576_+\|type-VII-secretion-AAA-ATPase-EccA	gnl\|CDD\|188437	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA. This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking].	1.7666e-173
NZ_CP014961.1\|WP_131804371.1\|704144_705587_-\|hypothetical-protein	gnl\|CDD\|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	8.61698e-05
NZ_CP014961.1\|WP_079493757.1\|699211_700429_+\|hypothetical-protein	gnl\|CDD\|373961	pfam15598, Imm61, Immunity protein 61. A predicted immunity protein with an alpha+beta fold and a conserved arginine. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, which usually contains toxin domains of the Ntox40 family.	2.47636e-29
NZ_CP014961.1\|WP_005064841.1\|727071_727365_-\|hypothetical-protein	gnl\|CDD\|181179	PRK07948, PRK07948, putative monovalent cation/H+ antiporter subunit F; Reviewed.	7.33479e-38
NZ_CP014961.1\|WP_005085539.1\|721892_723392_+\|type-VII-secretion-integral-membrane-protein-EccD	gnl\|CDD\|274855	TIGR03920, T7SS_EccD, type VII secretion integral membrane protein EccD. Members of this family are EccD, a component of actinobacterial type VII secretion systems (T7SS) with ten to eleven predicted transmembrane helix regions. [Protein fate, Protein and peptide secretion and trafficking].	5.22913e-56
NZ_CP014961.1\|WP_005085538.1\|717764_721742_-\|type-VII-secretion-protein-EccCa	gnl\|CDD\|274858	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa. This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP014961.1\|WP_032701720.1\|712582_714325_+\|AAA-family-ATPase	gnl\|CDD\|223531	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility].	1.33654e-58
NZ_CP014961.1\|WP_005085537.1\|716265_717768_-\|type-VII-secretion-integral-membrane-protein-EccD	gnl\|CDD\|274855	TIGR03920, T7SS_EccD, type VII secretion integral membrane protein EccD. Members of this family are EccD, a component of actinobacterial type VII secretion systems (T7SS) with ten to eleven predicted transmembrane helix regions. [Protein fate, Protein and peptide secretion and trafficking].	5.02162e-28
NZ_CP014961.1\|WP_032701723.1\|725114_726725_+\|type-VII-secretion-protein-EccE	gnl\|CDD\|274857	TIGR03923, T7SS_EccE, type VII secretion protein EccE. This model represents the transmembrane protein EccB of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccE1, EccE2, etc. This model represents a conserved core region, and many members have 200 or more additional C-terminal residues. [Protein fate, Protein and peptide secretion and trafficking].	2.18303e-56
NZ_CP014961.1\|WP_005085540.1\|723388_724885_-\|type-VII-secretion-protein-EccB	gnl\|CDD\|368288	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B. EccB is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.	7.35859e-177
NZ_CP014961.1\|WP_005085521.1\|703368_704127_-\|hypothetical-protein	gnl\|CDD\|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	0.000211863
NZ_CP014961.1\|WP_005064840.1\|726748_727075_-\|monovalent-cation/H(+)-antiporter-subunit-G	gnl\|CDD\|237169	PRK12674, PRK12674, putative monovalent cation/H+ antiporter subunit G; Reviewed.	4.8887e-26
NZ_CP014961.1\|WP_100247137.1\|714847_716230_-\|type-VII-secretion-associated-serine-protease-mycosin	gnl\|CDD\|274856	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin. Members of this family are subtilisin-related serine proteases, found strictly in the Actinobacteria and associated with type VII secretion operons. The designation mycosin is used for members from Mycobacterium. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair].	8.40055e-113

>NZ_CP014961.1|WP_005085526.1|706467_706794_-|hypothetical-protein
MNQPQQVVRSRTGSIAVVTTERGLPTAIKIDQRELSRSPQALATEILDLCKLSAIRQQVARRKELQDHKYAAAVCRALDLASEADLAAAEEKLQNDDDDLPDTWLRSV
>NZ_CP014961.1|WP_005085525.1|706090_706471_-|hypothetical-protein
MSSLADSILARVAKQRDLMLAATDECRSTKVRVTSKDKAVSVEVDAYGAMTGLWLTSQAQKLGADALAALIVQTAAAAAQAVLERQGFLTGEFSKRFSNLRNEPLRRWDGTMFTPEPGPSPSSSSG
>NZ_CP014961.1|WP_005085524.1|705643_705979_-|hypothetical-protein
MAIDDAAIAGIRGAKSAETIELKLEQARVWLKKIAALQAGLEKSKTVASSMGAWGQVPQFQSSYDIKANFTETQLNDIRTSLDKGIEYCKAFEATVRDVFAALHGASQTLD
>NZ_CP014961.1|WP_131804371.1|704144_705587_-|hypothetical-protein
MSGDDDNYGPGTKEGTSGIIFLYRALTGGSSNDWSRVNNSQVRKIDDPNLSSLRSKIGDFEKKAIKVTDEVFGDGLEYIDVYNRVKDSNVQGAHDDAEKWKQISANIESARSAFSDFLGNGNLGWEGASKDAAVASARAALDDFNTLQRSAKAMSEVVKKYAQTADETKSQIVSVYSDYKHDVIDRANSEYSAHVDEAKHDYDSYAQTVMNDPYRAGVNGVKDNVPNVAVYGNANAPKPFQAPATTPGTNAPSSSPPSSTSNGAAKPSSVDPKSLVPDKKTTPTNTPTNQAANPAQQAAQQAAQGASNAAKGATDAAKSAADSAKNALDQGLQSLSSLGDLANGNKSLPEGALGLGPIGAKTADALKNLGGRAAGGAGGGRGASSSAPGMRTNTTPIEATKTAATQQSPAASRAGVGASGAAGGGGAPAAGARGAGADGKEHKSNKALRRVQNELFNDSEAVVSVLGAAEEKPSKDTGKD
>NZ_CP014961.1|WP_005085521.1|703368_704127_-|hypothetical-protein
MEKLCKIDLLALSIINRNRGQDTLPYPLRFTQGQKFSLREDYNKYEHTVLQRFNEGDLAAYHSEIEILLGASDIRVASYAGNAQRMSRIVAARRDQLGCLALQHETEDTVTIYRLASAYEVGGAVARALSFGKPGAIARAVLPGVTMPQSYADSGYDPSEQILVRDAVKHEIFPKLDAQVRQIGTIQSHWQHARKWGWSREKETLVWVDTSQGAYILSRDFFTVSPMSIAVLEERINHLIAADVQAIRALRS
>NZ_CP014961.1|WP_005085520.1|701862_703347_+|hypothetical-protein
MTRTGTGIGRWGWIVAAVLTVVVVAGGVTATILLVRRSDTPSVGGPDVVGVDPQYLLAPIKSTQPTTGWTFRLQDAIPEATGSLAYFGPVIANRAYYIATDSRQKPGAKPGAFISTRTWVFGVDLATGKLALAPVELPGSAQCVTNGPTMILCIDDVTEGREKQVWVIDSKNGAIIHSGPTNLSPYNTKHGPYVQQYGAYALVTVDKPEFGETGWYGVGSRAELTWHVPSTGNPIYGGDVFSPDWPTPTMVATDREVQVDGKTQTEYIVFSLADGTVFHDKEYPASGPAWVTADGWVTNVLDDNVDAIAFYDNTGKRINLIKREGKNRLSLFSPSHYGLPIVLDETPSGEETWNVYDTHGQKLVALHGIEGYSKASAATEGRIVGSHVFFAPGEHETGEAPVWTQVDLKTGKPGTSCNKMDLGEPGYLASDGKVVITRPWNTVGDKEDHVNAVDTSNCAVLWDIPIPMGKDRIYRRGNTILRNTDVQLEEVVVS
>NZ_CP014961.1|WP_131726083.1|701329_701866_+|hypothetical-protein
MTASDGDSPTGPIDKLEAVEVPRRMWLTVCAAVVAFVGVAALIVCVVAAFTVPRPTLRPIAASESMSDGQARAVAEATVRLWMSERNEHHQGNMAELTCHSDAGTTALYQLRHLTDNNAIGMLEALGFGDFTRKPGEWRLYVFINKSTTGDSTRIFRFQIQDGGLRVCDVMNLKVAEL
>NZ_CP014961.1|WP_005085517.1|700796_701333_+|hypothetical-protein
MDARAHSVGKWRLLISGVRPVEWFLLFVGALCGVAAVVLFAVLWWPPPRAQLTVTAPISEQQKQVEQIYRQYIESRNRADVVGMRALTCSTPSGNVAKGLEILESGDSLPVRVDRVEGFVNYSEIGVGKVRIDGVHRVSALTDEGRALLKSQEDGDGFQTGKATLVNEGGWKMCGGAV
>NZ_CP014961.1|WP_131726082.1|700425_700785_+|hypothetical-protein
MSRTVDTVITVAFFVGLVPLVAIACIFAFWNGVRGYSGKTESNASSYSFFIGPVGIPIATLLCYLVALILACLSSGYTFYYPLVALGVGFVLTLALFSVSERFRSEHYRSVYRQRETKN
>NZ_CP014961.1|WP_079493757.1|699211_700429_+|hypothetical-protein
MNVDVSPELSAWANRAQYQVSQGSMSQDGRTVLWSSGGEVRIFVASRSDGWFQVTQSDRMQQESFLLCASSMTVVERYLFGRLGRSVRGRRLPLLSYPVAPLREGWKTEPVVLDRVSRLALMEPTGHPIAIVGADPTSGNAQLAALSVFVSADLKDVESSFLAPTGRPLFTTRAEAKEPIEEIPDFTGDIDVNGALVTYLRNLDQHGFINAREALVDAYGPAIALLVRSKISSVLDGAEARKMLTLPAAVSELKELHPEFSLAALEAAVLNSRNRGGAVPIEVDDLASLIMEDEAANDVPWDHYMLFTYFGDRRVGVSDFQYLGRQWQPGFLDNPFDIVDRLRSIREAMLDRDGRAWDAGVIIVDHASRRGRLFVFYGEDAEFWDMTPATQKAIAERGLQLIEQA
>NZ_CP014961.1|WP_005085533.1|710761_712576_+|type-VII-secretion-AAA-ATPase-EccA
MADTRDAQRVFDAGVLSLGIAIDGLETDRDVAYAAMAFKRATEYDPEMCDAWLGRAAAGDTSPEVLFNLYRTSTATMFREQRRLGLQPRALAGRFQTGLYIDYTLSTFTEAWLAYAASLSTAKDYGEAESVLDELDKLRERMADGNSEAQEICSYVRATIHFTTQRWPDVLTILANSASFEDEYIAAGAHLMVGSACAQMGLFGEGIRRLDQAIAGPISGVKRAAEFCKGLTLREMGKEEDARVIFERIYSEEPGFAANATALRDTKYRLIITTQEIIDSRTDKWDPSSARSAEDIGSEDAAERNNQYLAAAQAELDRQIGMTEVKTQVAKLRSAAKLAKVRGDKGLSSASRSLHLAFTGPPGTGKTSIARVIAQTYCGLGFLKTPTVVEAKRQDFVGQHLGSTAIKTDALIDSAMDGVLFIDEAYTLIQTGLSGGDAFGREAVDTLLARMENDRDRLVVIIAGYDGEIDRFLAANDGLASRFTKRIRFESYTPTELGDIGRVIARSRDSDLSDAAYDELVASCAALYSAEAVDQTGQIRRKVDLAGNGRFVRNVIEVAEEEREFRLSEEHGLAVDELDEDALRRIESADMKAALDTVLRMLTN
>NZ_CP014961.1|WP_032701720.1|712582_714325_+|AAA-family-ATPase
MNDPNDPPSERPDPTTPWREPIPDGLGQEQLNPPFGRWPQGGNNAAHPNFGAPPNSSAPLPSPKAHKLSRRFRSQQTPLAPSWDPEPLSMYGAPHHPHDMRTATNDPSSGATFTQPPAPGSMPPPVVPTETRPRSELGPQQPYYSRPEPLAENGGVPPSVPPFLPPALPPAPGPLVHEAAQHPGVQQPPSAEGRQAWLENGRVPDSRAYTDGRSPYGSPSTHRVEGGEPSAQPPMQPPHSYHGTHEPVNTPFTSAQPMPPPQQLDFQRPMLPSVDQLGLIRSAKPLPNRGWRKVVHRLSGGAVNPGESSAEATRRALIDRINAPVRGDYRIAVLSLKGGVGKTTTTFSLGATFASLRGDRVIAVDANPDFGTLAQRGPDETRSTTRDLLSDSNINRYSDVRRHTSQSASRLEILASERDPASSELFSEDDYRAVMRILQRFYNIIITDCGTGLMHSAMAGVLDEANALIVVSSPAIDGARSALATLDWLDHHGYSHLAHQAVVVISSSRPGASSVDLEQLRRHFLTRARMVHTVPFDSHLAEGLEISLDLMNRKTRFAFMELAASVADGFTQATRDRRLT
>NZ_CP014961.1|WP_100247137.1|714847_716230_-|type-VII-secretion-associated-serine-protease-mycosin
MPLIWLCAPPAVAFAVDPPIVQAGPPPSGSVGPTEPTEQKSVCARTGVRNGTDLSLVPSAEMMLDYRTAWRYSRGAGQKVAVIDTGVTPNPRLHVEGGGDYVSGTDGLQDCDAHGTLVAGIIGAAESSSDAFSGVAPEAQILSIRQNSSSFAIKGSGADKNNPSSNSPGYGNTTTLAYAITRAVDMGSSVINLSEVACAPVGLQIDDAALGRAVRYAFERNVVVVAAAGNVSKNGICQNQNETKDPNLPIEAAWSQVRTVASPAWFSDYVLTVGALNKLGQPADFSLSGPWVGVAAPGEGITSLASDGPGVINGVYGQDGLAPINGTSFATPFVSGVVALVRSRFPELNAAQVIDRIKRTARTPDNGPNIASGYGMVDPVAALTASVPPSDQMPNPTKTTAVSLPKRSVEATRARNIILAGTALVIAAMGAIWALYLPRRRREEATSPITDTAATDIKQG
>NZ_CP014961.1|WP_005085537.1|716265_717768_-|type-VII-secretion-integral-membrane-protein-EccD
MTGIRELSRDQIVSAEAEHVRVSVFGDRTQLDIAIPLDIPIASYLPELAQLVLSRGSSNDADANSRESRKNHWVLRHVDSNTPLPANSSLRSNKIKNGSQLVLSSERTLSAPTLYDDVVDAAARLNRSSYAPWDATTARNMALAGVNLVALVLTSFLISMPLSGQLAAVCLLCIFTVGTLLAGAAVAYRSFRNAVVASSFLWACIPVSTAVSWVSLKDLGEFGIAGTCLAMLAFNYSAYRLVGTGLWGILAATVVFVLCGTTALIQALLHPRIEITGTVLTLGATLLLLTVPKLVSPLDQFRAPTMEIESADEAELFENPFNHQPNGDPIRSEGSVESLPTAESVRQRVELASLVRSSLYTGLIVTAGIGLNVTIHPTTETNWKTLVFGFAILGVIALRIRDRLTKLERYSITIPTLISFLAMCITAQFGTAIDALIAYGATTGIAVTVALVEAFAGNSWKKSTKVSAALTYVDYILVASLIPLSLWVLDSYRHFGSVRW
>NZ_CP014961.1|WP_005085538.1|717764_721742_-|type-VII-secretion-protein-EccCa
MPGGEVNLQAPPEVPRVIPGNLFMKLMPFVMVVAVIGMLALMVTVGGRNLATNPMFMMFPMMMVMSMVGMFMGGGGRSGKAAAELNEERKDYFRYLANLRDDSDSTGEAQRTALEWSHPDPRTLVDVVGTRRMWERRPSDPDFCHVRVGVGTHRLASRLLAPETGPPEDLEPVSTVALRRFVKAHSVVHALPTAVSLRAFPTISLEGERKLTQRLVRSMLLELCVFHGPDHVQVAVVTANPDGQNWDWVKWLPQAQHSTAHDGIGTVRLVFPTLELLETSLATELGERGRFTRNAQPQQGLKHLVVVIDDGYVSGDERLVTEAGLDSVTVLDLNAGSERRPPSKRGLQLVVESGDVGARTAVGVERFASPDSLSVAEAQATARRIGRFRPANAAHIVSFESESRASDPGLMALLKIPDAAEIVPEQVWRPRTPRERLRVPIGITPNGQPLELDIKEAAENGMGPHGLCIGATGSGKSEFLRTLVLSMITSHSPDALNLVLVDFKGGATFLGLDGVPHVSAIITNLEDELILVDRMRDALAGEMNRRQELLRASGNFPNVTEYERARANGADLDPLPALFIVVDEFSELLSQKPDFAELFVMIGRLGRSLHVHLLLASQRLEEGKLRGLDSHLSYRIGLKTFSAGESRSVLGVPDAYHLPSVPGSAYLKTDASEPTRFNASYVSGEYVKPKGAGRSARTSNLGAMAPKLFTASPVPMEPKPTVKQPELAEVSEPVSHSPIKRTLLDVVVSRIRGHGRPAHEVWLPPLDASPAVNQLLPEPEWSAPANINAKLVMPLGIIDRPYDQRRDVLMIDLSGANGNIAVVGGPQSGKSTALRTLIVSAAATHTPEQIQFACLDFGGGTLTSLTNLPHVSSVAGRMDGDRIRRTIAEVSGLLRAREQRFRDLGIESMRDFRQRKAQLARLSPESAAQDPLSQDKFGDLILVVDGWASIRSDFEALEPVLQSIAIQGLSYGIHLAISASRWMEIRPAVKDMLGTRIELRLGDPIDSDMGRKVAELVPVGRPGRGITSERLHMLVALPRLDSSSDIEDLPDGVSRTVEMVGNHYRGRHAQRVRMLPHDLDRAAVIEAAAKAHKISRSKIAIGIDESELAPVVLDFDAQPLLVAFGDTECGKTSLLRNIALGIMENATPDEAKIVLVDFRRSMLGAVEGDHLGGYATATASCNELMKSLAGALQDRLPPEDITQQQLKERSWWSGPDIYVLIDDYDLVAVSNSTLSPLLEYLAQARDIGLRVVVTRRIGGAGRALFDPFLGRLRDLSCNGLVMSGSKDEGALFGGYKASPMPPGRGMLVSRTMPSGVIQLSRMPEL
>NZ_CP014961.1|WP_005085539.1|721892_723392_+|type-VII-secretion-integral-membrane-protein-EccD
MTLPPSLADLEPDGSSEPELTRVTLLVGGLQLDVGLPPNLSVSAFIGDVIDIANRQLRVHDRSAEVVFDNTDGRWSLAKLGAAPVDPAKSLAEADIYDGDVLALREVGRVTAPILFDDIEAAGEDSVRRPSDIGVFLRNRSFIAYFGTALVCAVVSALLIHRQAENNPWAGVASIVCGAILLIALSVLAFKRVDNFGARSLGLAVVATPLVAAGILYVVPNGHGLLSLPLSFSLTALISLFTLQISREGRTFHTFVIVVSILGGAASLVYLYARVDSRAIGAVLATVSVFIVYVSPRLTIALSKLPIPRVPTAGEPLDDIETQGGTTVEGVNAIGKQVIPTEEGMVIRVNRANQYLSGILAAAALAGAVGAYLAVDVSDGFFWQGVVFAGAVAAVFCLRGRSHHDVAQSATLIGAGMVTGVAVLSKLVVFLSGWETRAVVGLIALVFLIIACGVIAPRLEFSPVMRRWVELLEYAAIASVIPLSFWIIGLYAFARDMRI
>NZ_CP014961.1|WP_005085540.1|723388_724885_-|type-VII-secretion-protein-EccB
MPAQITTRAQVNGYRFLLRRLEHALIRGDSRMIHDPMRGQMRSLAVGLVIGILITGACGILAFFKPSPAIGNAQILLTKKGGALYVRIGERVHPVLNLSSARLIAGKPEQPAAVDDKKLNALPRGPVVGIIGAPNALLPNADSSTSHWTVCDTFDTPDVSTDTGTGKLLTTVLTNKPQLDREIHAADSREMLLVDYEGETYLIYDGVRAKLSNDPIVIRALHLEQAKIRPISAGLLNSFPLVEPIEPIFVDGASEPSVIRPDLRVGSIIKTNDSRGEQLYVVLRNGVQAISTATADIIRYSDAGSVRDTKEVPPSMISTVPVVHDLPIDKYPQTTPVVSDYNHDRVVCQAWEHGNTDPAAKMRLLIGHRLPMPNEAQVVQLATADGGGPGLDQAYLPPGTGEYIQTTGSGTDVGSLGSLYYVSDSGQRFHIKDLSTVSALGLTGWEDKEAKINRPQAAPWSIVSLLPPGPELSQQAALIAHDGMSADPKGLKVDPPKS
>NZ_CP014961.1|WP_032701723.1|725114_726725_+|type-VII-secretion-protein-EccE
MADALALEFLVAAGIMIALLVGKSWWIGGVAGLLLSLLLVVRIRGTSVPRALAARLDFFFGRQSKTRKTPPAEPFDTPLDGGAQIGFRWDGRTLLTLLKIEEKPQALTVMEPGMTVSGETVSVELLVECMRQFDIRIDSIDVISQGARSFGHTRIASVYDAVLGPLPAIAQRSVWIAIRFDPAQCAEAVTRRGGGRNGILRAAITATRRVANQLTEAGLHTRILTAAEIAQATNQLADGVNLANLEENWTCCSEGNFRLYSYSLKGNALSTAGLGMVWTVPSYSTTVCVSLQNSVKSDYTRIRGLVRFDSHGYGGDINLPGLVPLRGQQFNALVSSLPLPPPRRPLGSWVYGRGTEDFRDLALPASGCGQVIGADEYGRAVALPMFGQQIERVEISGTLHLAQQVVLRALALGARVLVHTRRPALWRGMVGEVGDNSLLWVTEFNRGSIQAGSDRNYSVAVFDGVVEQVVRIGVTAMIVAAPGTVPSPDADVSLEQLDEHSDTVKVSTSAGSAVVSMVATDEEMRYLKESLNVQYA
>NZ_CP014961.1|WP_005064840.1|726748_727075_-|monovalent-cation/H(+)-antiporter-subunit-G
MNAFLDAISGVLVLLGSALALTAAMGVVRFPDTLARMHAASKPQVLGLLLVLAGAALRLRGHADVSMIVLTGLFTIITAPVVAHRVARLAYHERSVRDDLMTTDELER
>NZ_CP014961.1|WP_005064841.1|727071_727365_-|hypothetical-protein
MSLVWHIAAVFLVAAASITTYRLLAGPNTLDRLVAVDTLVAVTMCALAAWAAYSLDSTVLYGMVALSLISFLGSVSVTRFRVPDTAIDPDDPRSRPR

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Crispr_ID: NZ_CP014961_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014961_2

1107176-1107263

Orphan

Consensus_repeat	Method
CGGCTGCTACAACGGCGTGTGCGGTGGCTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014961_2

>merge|NZ_CP014961|2|1107176-1107263|CRISPRCasFinder
CGGCTGCTACAACGGCGTGTGCGGTGGCTGGAACCCCGGCCAGGGTGGTTGGGGCCACGGCTGCTACAACGGCGTGTGCGGTGGCTGG

>NZ_CP014961|2|2|1107176-1107263|CRISPRCasFinder
CGGCTGCTACAACGGCGTGTGCGGTGGCTGG	AACCCCGGCCAGGGTGGTTGGGGCCA
CGGCTGCTACAACGGCGTGTGCGGTGGCTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014961.1\|WP_005066010.1\|1115038_1115785_-\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
NZ_CP014961.1\|WP_005102410.1\|1105274_1106411_+\|lipase	unknown	unknown	gnl\|CDD\|367570
NZ_CP014961.1\|WP_074232589.1\|1108278_1108875_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225767
NZ_CP014961.1\|WP_005063541.1\|1115910_1116693_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319911
NZ_CP014961.1\|WP_024571189.1\|1112730_1113165_+\|DUF779-domain-containing-protein	unknown	unknown	gnl\|CDD\|377532
NZ_CP014961.1\|WP_005065989.1\|1101716_1104119_+\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319795
NZ_CP014961.1\|WP_052539877.1\|1113258_1115049_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
NZ_CP014961.1\|WP_005102528.1\|1116719_1117925_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|179663
NZ_CP014961.1\|WP_005063562.1\|1099090_1099822_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|236115
NZ_CP014961.1\|WP_005100882.1\|1099824_1100925_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293841
NZ_CP014961.1\|WP_005063546.1\|1111229_1112750_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143434
NZ_CP014961.1\|WP_005063556.1\|1105036_1105252_+\|antitoxin	unknown	unknown	gnl\|CDD\|379416
NZ_CP014961.1\|WP_005063565.1\|1097416_1097998_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_017205539.1\|1100921_1101599_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP014961.1\|WP_005065999.1\|1106447_1106891_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|378454
NZ_CP014961.1\|WP_005100846.1\|1104148_1104982_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225852
NZ_CP014961.1\|WP_079461375.1\|1097977_1099066_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983
NZ_CP014961.1\|WP_016341948.1\|1107299_1108220_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274648
NZ_CP014961.1\|WP_062919442.1\|1108825_1110838_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340868
NZ_CP014961.1\|WP_005066003.1\|1110998_1111154_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239527

Protein	Function_ID	Function_description	E-value
NZ_CP014961.1\|WP_005066010.1\|1115038_1115785_-\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	1.51257e-69
NZ_CP014961.1\|WP_005102410.1\|1105274_1106411_+\|lipase	gnl\|CDD\|367570	pfam03583, LIP, Secretory lipase. These lipases are expressed and secreted during the infection cycle of these pathogens. In particular, C. albicans has a large number of different lipases, possibly reflecting broad lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue.	5.45097e-17
NZ_CP014961.1\|WP_074232589.1\|1108278_1108875_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|225767	COG3226, COG3226, Uncharacterized protein conserved in bacteria [Function unknown].	7.56192e-08
NZ_CP014961.1\|WP_005063541.1\|1115910_1116693_+\|VOC-family-protein	gnl\|CDD\|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.84839e-40
NZ_CP014961.1\|WP_024571189.1\|1112730_1113165_+\|DUF779-domain-containing-protein	gnl\|CDD\|377532	pfam05610, DUF779, Protein of unknown function (DUF779). This family consists of several bacterial proteins of unknown function.	2.92171e-69
NZ_CP014961.1\|WP_005065989.1\|1101716_1104119_+\|cation-translocating-P-type-ATPase	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NZ_CP014961.1\|WP_052539877.1\|1113258_1115049_+\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.000155006
NZ_CP014961.1\|WP_005102528.1\|1116719_1117925_-\|DNA-polymerase-IV	gnl\|CDD\|179663	PRK03858, PRK03858, DNA polymerase IV; Validated.	0
NZ_CP014961.1\|WP_005063562.1\|1099090_1099822_+\|enoyl-CoA-hydratase	gnl\|CDD\|236115	PRK07854, PRK07854, enoyl-CoA hydratase; Provisional.	5.5316e-136
NZ_CP014961.1\|WP_005100882.1\|1099824_1100925_+\|hypothetical-protein	gnl\|CDD\|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	4.22158e-68
NZ_CP014961.1\|WP_005063546.1\|1111229_1112750_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143434	cd07116, ALDH_ACDHII-AcoD, Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like. Included in this CD is the NAD+-dependent, acetaldehyde dehydrogenase II (AcDHII, AcoD, EC=1.2.1.3) from Ralstonia (Alcaligenes) eutrophus H16 involved in the catabolism of acetoin and ethanol, and similar proteins, such as, the dimeric dihydrolipoamide dehydrogenase of the acetoin dehydrogenase enzyme system of Klebsiella pneumonia. Also included are sequences similar to the NAD+-dependent chloroacetaldehyde dehydrogenases (AldA and AldB) of Xanthobacter autotrophicus GJ10 which are involved in the degradation of 1,2-dichloroethane. These proteins apparently require RpoN factors for expression.	0
NZ_CP014961.1\|WP_005063556.1\|1105036_1105252_+\|antitoxin	gnl\|CDD\|379416	pfam14013, MT0933_antitox, MT0933-like antitoxin protein. This family of proteins contains the MT0933 protein, which has been identified as an antitoxin to /protein MT0934. This family of proteins is found in bacteria. Proteins in this family are typically between 61 and 90 amino acids in length.	4.21227e-08
NZ_CP014961.1\|WP_017205539.1\|1100921_1101599_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	8.59363e-22
NZ_CP014961.1\|WP_005065999.1\|1106447_1106891_+\|SRPBCC-family-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	6.54669e-14
NZ_CP014961.1\|WP_005100846.1\|1104148_1104982_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	2.00141e-48
NZ_CP014961.1\|WP_079461375.1\|1097977_1099066_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.58016e-34
NZ_CP014961.1\|WP_016341948.1\|1107299_1108220_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274648	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes one such subfamily, exemplified by Rv1855c from Mycobacterium tuberculosis. [Unknown function, Enzymes of unknown specificity].	3.16234e-71
NZ_CP014961.1\|WP_062919442.1\|1108825_1110838_-\|MFS-transporter	gnl\|CDD\|340868	cd06179, MFS_TRI12_like, Fungal trichothecene efflux pump (TRI12) of the Major Facilitator Superfamily of transporters. This family includes Fusarium sporotrichioides trichothecene efflux pump (TRI12), which may play a role in F. sporotrichioides self-protection against trichothecenes. TRI12 belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.77048e-66
NZ_CP014961.1\|WP_005066003.1\|1110998_1111154_+\|hypothetical-protein	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.90021e-05

>NZ_CP014961.1|WP_005065999.1|1106447_1106891_+|SRPBCC-family-protein
MAAKLNSSIDVPLPPEEAWAHASDLRRFDEWLSVHTAWRSALPETLEKGTVIDSIVCVKGMYNRVRWTLQKYDPPTGLFLDGQGRGGVKVKLRVTISPKGSGSVVDFNLHLGGPAMFGPIGAVVAAALRSDIDASLAKFVQVFAAAP
>NZ_CP014961.1|WP_005102410.1|1105274_1106411_+|lipase
MLVLITAACARVEAEGVAPQPPSPPPGEVLSDVPLSLAPDLDAIADGHLIRYMSTSGATGTPTEVTGVVFAPKGEPPQAGWPIVSVGHGTTGLDDECAVSRAPDLRGYIWLVRNLSKRGWVVAITDYEGLGVPGPHPYLEPRSEGFNVIDAARAAVSLIPGASTKWAAIGASQGGQATWAASELAGNYASELEFVGSANLSPAADLTDMATHVGDGRYHWSQLSMMPTLLTGLSVTVPELRPENFLHGSFQDIPQDKALLLGCHNGLDPARSAAIGRLRAKDFHGTSPADPIVFAAALKRIALPLGPASGPMFVYAGGADRLIEAGWIHAAVRRACALGDTVQEVVSPGKGHVDPEGERLGVQWIADRFAGLPAPSNC
>NZ_CP014961.1|WP_005063556.1|1105036_1105252_+|antitoxin
MADFKGLIDKLKSLLAGNKDKVNEAVDKVGDTIDSKTGGKYSAVVDKVQDAAKSAVEKVEGAAAPKDGDAQ
>NZ_CP014961.1|WP_005100846.1|1104148_1104982_-|class-I-SAM-dependent-methyltransferase
MLVRVTDPVKITLTGAPETMLATLYGRAQDATSPNSVLHDHYAAEAVARIDYDFSKTKIKGTQAIGVALRARQLDDWTSEFLTAHREATVLHLACGLDTRVFRINPSETVRWVDVDYPDVIALRRALLPCREGDYRMIGSSVSEATWLDSIPADRPTLAVFEGLTMYLTEAEGQSLIRRITGRFPSGQLAFDCYGSIGIKLQKLVPAVRNAGATLHWGIDDPGQIEALHPGLRCVSDLRSTDVAGEEHLPLSGRIQMKVISHLPALRDIGRIMRFSF
>NZ_CP014961.1|WP_005065989.1|1101716_1104119_+|cation-translocating-P-type-ATPase
MATIEGLTISGLTAAEVAERVAQGKTNDVPSRAARSVSDIVRANVFTRINAILGVLLIIVLSTGSIINGAFGLLIIANSAVGIIQELRAKQTLDKLAIVGQTRPLVRRDGAATALAPNEVVLDDIIELGPGDQIVVDGEVIEESALEIDESLLTGEADAIEKTIGSQVLSGSFVVAGSGAYRATKVGREAYAAKLAEEASKFTLVHSELRNGINKILQFITYLLLPAGALIIYTQLFTTDDSWQESVLRMVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVQELPAIEGLARVDTVCADKTGTLTENGMRLADVRFPDRDGDEDALAVLAQLAADDPRPNASIAAIAEAYDTPPGWETTAIAPFSSAKKWSGASYGDHGNWVIGAPDVLLDPADAIATAAEEIGARGLRVLLLASAELSVDDAHAPGAVTPRALVVLEQKIRPDARETLDYFASQHVSIKVISGDNAVSVSAVAQTLGLTGAAVDARTLPTDTDKLAATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDGVNDVLALKDADIGVAMGAGSSASRAVAQIVLLDNKFATLPYVVAEGRRVIGNIERVSNLFLTKTVYSVLLALTVGLAGLGSKILHYGAVPFPFQPIHVTIAAWFTIGIPAFILSLAPNNERAQTGFVRRVMLSAIPSGLTVGIATFLSYLLARQILHVSGNSTQASTAALITELVAAVWVLAVVARPYQWWRVVLVALSGLGYVAIFAIPLARKAFMLDPGNLAVTGPALGIGIAAAAVIEAVWWLQGKWSGQLRHFWATGED
>NZ_CP014961.1|WP_017205539.1|1100921_1101599_-|class-I-SAM-dependent-methyltransferase
MTSNELPNWDATYQGKGELFQGEPPWNIGEPQPELAALIDAGKFHGTVLDVGCGHAETSLRLAALGHTTVGLDLSPTAIEAARAAAAERGLTNATFEVADITDFSGYDGRFNTIVDSTLFHSIPVEAREAYLQSISRAAAPDASYFVLVFAVGAFPPGIGPNAVTEDELRAAVEPYWAIDELSSAYIHSNIPEVIPGANFEMPVFHKDEKGRNKQPAFLLQAHKR
>NZ_CP014961.1|WP_005100882.1|1099824_1100925_+|hypothetical-protein
MRALWVGAGAAIASTWIGRALRDVPQTLGASKGRIAEVAKGSPQYRGGTFHNAEPARQFSPDAETTTVVWDVLTRRSVGTPKGQVPLAVPEFAGPPADLAATWFGHSSVLVEIDGYRVLTDPVWSDRCSPSRVVGPHRQHPVPLELSALPALDAVVISHDHYDHLDMDSIIALTRSQNAVFVVPLGVGAHLRGWGVSPARVIELDWDQSHQLGKLTLTCTQARHFSGRSIARNTTLWASWAFAGPKHKVFFGGDTGYTKAFKVIGDTYGPFDLTLLPVGAYNTSWADIHMNPEEAVQTHLDLATAQAPLLPIHWATFNLALHPWAEPIERVLAAAEEQGVTVVTPRPGQRADARQPAAPDDWWRLS
>NZ_CP014961.1|WP_005063562.1|1099090_1099822_+|enoyl-CoA-hydratase
MIGVTSDGPVTTIELQRPERRNAVTYELALAFAEEVKKAAETARAIVVTGQGTSFCAGADLSSGAPDPDKFADAWQHSIKSVDAADIPVIAAVNGPAIGAGVMLAMVADLRVVSETARFQFPVAKYGIALDNWSIRRLTSLVGYGRARAMLLAAEPLDAQTALQTGMANRIGELADAQAWAAELAGFAPLALKHAKRVLNDDGAFEDQWPEHKELFDKAWGSQDIIEAQVARIQKRPPNFQGA
>NZ_CP014961.1|WP_079461375.1|1097977_1099066_-|NAD(P)/FAD-dependent-oxidoreductase
MTTVAVIGGGQAGIAAGYFLRRRGLEPLSRRQPADAPGHGFVILDHSPGPGGAWQFRWPTLTLDNTNRIYQLPGLPFDEMGTIRASTAMPRYFGEYEDRYALDVRRPVHVRAVRPARGGFTIDTSVGEFPVDGLINATGTWDKPFVPFVPGAGTFRGRQLHTHDYQRPEEFTGQHVLVVGGGISAVQLLIEIAGIDSVTTSWVTRREPVFVTDLTVDRLRAAVAGVDERSRRGEPQRSVVSATGLPWTAETAEAARRGILTRRPMFSRITPTGVTWPDGSALEVDVILWCTGFRHALDHLAPLHLRNGRGGITMTGRLLTQVAGQPAIHLLGYGSSASTIGANRASRAAVVELMNYLEGRTA
>NZ_CP014961.1|WP_005063565.1|1097416_1097998_+|hypothetical-protein
MCAALGVGLLSGGAAVAHADPAFPDLSGFAVVPPDGFFVTNENSSVRSIHFSTPDGIGCMFRASPNMTPTSRQRLSCDGAVPGIPGDAPNAPNVPGIGGASANVPGLGGVNIPGVGTCPMGTVAQKGDGAFEISKGAWSCGTKPEAPLLNVGQKLTYGNVTCAVGAGSVTACQVVTGDQKHGFVLQPSGSTSF
>NZ_CP014961.1|WP_016341948.1|1107299_1108220_-|LLM-class-flavin-dependent-oxidoreductase
MRFSIWGQTNQSWADLLDIAQYADDGTWRAFYAADHFMSHADTAEERTDFHEATALFAALAAATSRIRLAPLVLSMTFRHPAVLANWAATVDHVSQGRFTLGLGAGWQENEHQRYGLELGKPGARVDRFSEGLQVITGLLNEPATTVDGQYYRLAEGICEPKPLQRPLPILIGATQPRMLALTARYAHEWNQWSSPGTFREVSGRLDAAAEKIGRDPATIWRSTQARVIVTDGPQSEARAAETAAASPIPVLYGTAERIAEQMAPWAQEGVDEVILPDHLLGSGSARRDAYDALAQALRPLSNEKG
>NZ_CP014961.1|WP_074232589.1|1108278_1108875_+|TetR-family-transcriptional-regulator
MEEQPRGRRAEVIAAAIEVAGTMGIGGLTYRSVDAAANVPSGTTSNHFRTRDALLLGAILEIEKLRRAFWRALVTEINPTTVSDLVGIGTAYANGAVGAMSTRVRAYMALLMEGWSHPELREPLQRGRDAQIPRTLHLMCKVDPKTPQLHAEIFQDYLTGIIYQQLANPVADFNPRPGIEALLTALVTPPQTPRAAQR
>NZ_CP014961.1|WP_062919442.1|1108825_1110838_-|MFS-transporter
MISVQRRNLIFVAVLLGMLLAALDGTIVATALPTVVADLGDAGHQSWVVTSYLLASTVATAVMGKFGDLFGRRTVFITCIVIFAGGSLLCGMAGSMAMLVGARAIQGLGSGGLMVTATALIGEIIPMRERGRYQGILGAVFGVTTVIGPLLGGLFTDHLGWRWAFYINLPISVVVIMVAAGAIPALAKATRPVIDYWGIVLIGLGASALTLATSWGGTTYPWSSPVIIGLFASSIAAIGTFVWVESRVPEPILPPRLFRDPVFTICCVLSFVVGFAMLGVMTYLPTFMQFVNGVSATVSGLRTLPMVAGMLITSTGTGTLVGRTGRYKRYPVAGTAIMAIALVLLSRMNDSTPFVLQSLYLFILGVGIGASMQVLTLIVQNTARFDDLGVATSGVTFFRTIGSSFGAAIFGSLFSNFLTRELSSVNTPPRATQSPQALHALPHDAAVPVIHAYADSLDLVFLCAAPVAAVGFVLALFLKEVPLRGADTSLAVDMGEGFGMPNSVSPDKLLEIAIGNAMRGFPHVGLRKLREHAGVSMPIAPLWALVQANRFLRATGSAEVSRIAQWYRIPPEIVDPAFNELVANGYALRTNDHIWLTDSGREEVDKISEAINQYLIERLSRTPDFEDRADREQIQAALERISRRIVTDTDWRENPIAALPAASGAASPAR
>NZ_CP014961.1|WP_005066003.1|1110998_1111154_+|hypothetical-protein
MCGYGCLASLPEGASGCTTVELKTNFLGAAREGKLTAAVFRCTQLVLWPRG
>NZ_CP014961.1|WP_005063546.1|1111229_1112750_+|aldehyde-dehydrogenase-family-protein
MAKYAAPGTEGSAVTFAPRYENFIGGEWVAPADGQYFENASPIDGKVFTQVARGTAPDIEKALDAAHAAAEGWGNTSAAERSNALLRIADRMEQHIERLAVAETWDNGKPIRESLNADIPLAIDHFRYFAGVLRAQEGSISEIDHDTVAYHFHEPLGVVGQIIPWNFPLLMAVWKLAPALAAGNCVVLKPAEQTPASILVLMELIADLLPSGTVNVVNGFGVEAGKPLASSPRIAKIAFTGETTTGRLIMQYATENIIPVTLELGGKSPNIFMPDVMAADDAFLDKALEGFTMFALNQGEVCTCPSRALVHASIYDEFIARAITRVEAIVGGDPLDEDTMIGAQASNDQYEKILSYIDIGRQEGAQVLTGGDARKVAEYPDGAYIQPTVFAGTNNMRIFQEEIFGPVLSVAKFDSLDEALKIANDTLYGLGAGVWSRDMTNAYRLGRGIKAGRVWTNCYHQYPAHAAFGGYKKSGIGRENHKMMLDHYQQTKNILVSYSPDAAGFF
>NZ_CP014961.1|WP_024571189.1|1112730_1113165_+|DUF779-domain-containing-protein
MQRASSDEGSPGESRILINRVELTPAAAELLASLVAKHGPVMFHQSGGCCDGSAPMCYPRGEFRVGASDVLLGEVSRDTPFWMSADQFEYWSHTHLTVDVVPGRGSGFSLEAPEGVRFLIRSRLFTDDEVLALANQPVRTGADG
>NZ_CP014961.1|WP_052539877.1|1113258_1115049_+|hypothetical-protein
MHVGIRTVAVAAVCGLCVGAGVDARAVRPNLSIAGTPTTRSVSSQAVSLASFSDLLAAAAPQNDAAAQMNSVGGGAVSSTDLIGTVAKLLAAPNIMQSSVTPGINTAAVDTVDSPSSEPVDPPTGQPADPPAADEPAPPTNFPGERPAFGTPSYFAQLAFAVFHVVALPITVPVQFFLGSAEGVPTVIAAAINDLSGLLGQIPGLSPQQPTEPQPQQIAQSSSPLQKQAAAETGPTTDPEPPAEPLPTNFPGPRPAFGTPSYFAQLAFAVLHVLALPITVPVQAIIGKTEGVPSVIVAALNDLSSLLGQVPKLSAPVTDTKTTPQDSTSRQADKAAPTLDSASEKPETATSGADAKTSKIERNEHEGKTADKAAEAPKAEHETKPGAASEGTPKTDSAKEVVESKADPTKVVESKADPTKAVEPKADPTKVVEPKVDPAKVVEPKTDPAKAVEPKADTVAEPAKPESSKAEVAKPVTAKPETKVQPAKPESAGPVKVTRDSLKSTPGETGTTGGTKTTEGSKGSVTDSKTPAASTDTKVHDGLKPAVGAKPDKPADKPSTEKSSSEKSGSSSEGSSHSSESKSHSSEGKSHSGSKD
>NZ_CP014961.1|WP_005066010.1|1115038_1115785_-|peroxide-stress-protein-YaaA
MIVLLPPSETKHEGGDGPPLRLNELATPTLNPLREALVDELIALAAEPDACRQALGISASQDAEIQRNAELRISPTMPALHRYTGVLYDNLDVTSLRGASATRARERLAVGSALFGLLRADDPVPAYRLSASSKLPGKPTLAARWRPVLEPVLAELAAGELVVDLRSGSYAGLGRLPHAVTVDCLTEHPDGRRTVITHFNKAHKGKLARILAGSRAEPNDAASVATVARRAGLHVERDGNTLTIVVSP
>NZ_CP014961.1|WP_005063541.1|1115910_1116693_+|VOC-family-protein
MPTRDETPLGAPAWIDLASSDLEKSKAFYSALFGWTLQDAGPEYGGYINAHKDGKAVAGMITNNPEWNAPDAWTTYFATDDIDATLQKAVAHGGTNCLPPMEVPQLGYMALFADPAGAMVGLWQPLAHKGFQLVGEGGAPAWHELNTREYDRAVDFYTTVLGWNTKTEGDSADFRYACAQHDGAPIAGINDASVGQWALPEGVPAHWAVYFGTDDTDAGAAKATELGGVVLAPAQDTPYGRMALIRDTTGATFWLCSVDS
>NZ_CP014961.1|WP_005102528.1|1116719_1117925_-|DNA-polymerase-IV
MTGTASILHADLDSFYASVEQRDTPALRDRPVIVGGGVVLAASYEAKHCGVRTAMGGRQALRLCPHAVVVPPRFDAYSAASKLVFEVFRDTTPLVEPLSIDEAFLDVSGLQRISGAPSDIAAALRVEVRRRAGLPITVGIARTKFLAKVASRQGKPDGLLVVEPHEELSFLRPLPVQALWGVGSVTAEKLRVYGIRTVADVADLGESTLASMVGRAMGHQLHCLANNIDPRRVDGGRRRRSIGAQCALGRGPRADSEIDAIATQLMERIARRMRGTGRSCRTVVLRLRFGDYARATRSRTMPRPTTSTERLLSVARELVKDAGPLIKERGITLIGFSVSNFDPCGAAQLELPFSDAAENTLALDSTLDGLRNRFGTWSVTRANLLHGGGREEWGIPTFEDL

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Crispr_ID: NZ_CP014961_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014961_3

1208020-1208151

Orphan

Consensus_repeat	Method
GGCTACGGTCAGCAGCAACCCCAG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP014961_3

>merge|NZ_CP014961|3|1208020-1208151|PILER-CR
GGATACGGCCAGCAGCAACCCGCGCAGGGCTATGGCCAGAGCGGTGTCCAGGCAACTCCCGGCTACGGTCAGCAGCAGTCTGCTCCGGCGGCTCCGCCTTCGTACGGTGGCTACGGTCAGCAGCAACCGCAG

>NZ_CP014961|3|1|1208020-1208151|PILER-CR
GGATACGGCCAGCAGCAACCCGCG	CAGGGCTATGGCCAGAGCGGTGTCCAGGCAACTCCC
GGCTACGGTCAGCAGCAGTCTGCT	CCGGCGGCTCCGCCTTCGTACGGTGGCTACG
GTCAGCAGCAACCGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014961.1\|WP_074246547.1\|1200712_1201684_-\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP014961.1\|WP_062919454.1\|1196737_1197556_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226406
NZ_CP014961.1\|WP_005126840.1\|1209791_1210430_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|235544
NZ_CP014961.1\|WP_005116210.1\|1215366_1215969_-\|DUF1707-domain-containing-protein	unknown	unknown	gnl\|CDD\|377959
NZ_CP014961.1\|WP_005063403.1\|1220105_1221701_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit	unknown	unknown	gnl\|CDD\|178415
NZ_CP014961.1\|WP_062919457.1\|1214162_1215413_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369571
NZ_CP014961.1\|WP_005098726.1\|1195057_1196695_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234679
NZ_CP014961.1\|WP_005098875.1\|1212002_1213856_+\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|226646
NZ_CP014961.1\|WP_062919456.1\|1208442_1209768_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368653
NZ_CP014961.1\|WP_016893591.1\|1198185_1200606_+\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_CP014961.1\|WP_005116205.1\|1206097_1207219_+\|dimethyl-sulfone-monooxygenase-SfnG	unknown	unknown	gnl\|CDD\|274923
NZ_CP014961.1\|WP_005063441.1\|1197599_1197890_-\|chorismate-mutase	unknown	unknown	gnl\|CDD\|236117
NZ_CP014961.1\|WP_016893598.1\|1218030_1220109_-\|acetyl-CoA-carboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|227111
NZ_CP014961.1\|WP_005063432.1\|1204530_1205133_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_005063407.1\|1216864_1218034_-\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NZ_CP014961.1\|WP_074246520.1\|1210399_1211980_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP014961.1\|WP_052539824.1\|1205129_1205978_-\|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274680
NZ_CP014961.1\|WP_005063434.1\|1203386_1204289_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NZ_CP014961.1\|WP_005063435.1\|1202181_1203351_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NZ_CP014961.1\|WP_016893597.1\|1216055_1216841_-\|enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl\|CDD\|236109

Protein	Function_ID	Function_description	E-value
NZ_CP014961.1\|WP_074246547.1\|1200712_1201684_-\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.3388e-41
NZ_CP014961.1\|WP_062919454.1\|1196737_1197556_-\|hypothetical-protein	gnl\|CDD\|226406	COG3889, COG3889, Predicted solute binding protein [General function prediction only].	3.15792e-05
NZ_CP014961.1\|WP_005116210.1\|1215366_1215969_-\|DUF1707-domain-containing-protein	gnl\|CDD\|377959	pfam08044, DUF1707, Domain of unknown function (DUF1707). This domain is found in a variety of Actinomycetales proteins. All of the proteins containing this domain are hypothetical and probably membrane bound or associated. Currently, it is unclear to the function of this domain.	1.8494e-18
NZ_CP014961.1\|WP_005063403.1\|1220105_1221701_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit	gnl\|CDD\|178415	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain.	0
NZ_CP014961.1\|WP_062919457.1\|1214162_1215413_+\|hypothetical-protein	gnl\|CDD\|369571	pfam07883, Cupin_2, Cupin domain. This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel).	0.00621817
NZ_CP014961.1\|WP_005126840.1\|1209791_1210430_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|235544	PRK05647, purN, phosphoribosylglycinamide formyltransferase; Reviewed.	2.92664e-102
NZ_CP014961.1\|WP_005098875.1\|1212002_1213856_+\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|226646	COG4178, COG4178, ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only].	0
NZ_CP014961.1\|WP_062919456.1\|1208442_1209768_+\|hypothetical-protein	gnl\|CDD\|368653	pfam05887, Trypan_PARP, Procyclic acidic repetitive protein (PARP). This family consists of several Trypanosoma brucei procyclic acidic repetitive protein (PARP) like sequences. The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB; transcription of both loci is developmentally regulated.	1.35266e-12
NZ_CP014961.1\|WP_016893591.1\|1198185_1200606_+\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP014961.1\|WP_005116205.1\|1206097_1207219_+\|dimethyl-sulfone-monooxygenase-SfnG	gnl\|CDD\|274923	TIGR04021, LLM_DMSO2_sfnG, dimethyl sulfone monooxygenase SfnG. This family of FMNH2-dependent members of the luciferase-like monooxygenase (LLM) family includes SfnG, a monooxygenase that converts dimethylsulphone (DMSO2) to methanesulphonate. This step can be followed immediately by methanesulfonate sulfonatase (an alkanesulfonate monooxygenase - see TIGR03565) for the FMNH2-dependent conversion an inorganic form. [Central intermediary metabolism, Sulfur metabolism].	0
NZ_CP014961.1\|WP_005063441.1\|1197599_1197890_-\|chorismate-mutase	gnl\|CDD\|236117	PRK07857, PRK07857, chorismate mutase.	1.44015e-38
NZ_CP014961.1\|WP_016893598.1\|1218030_1220109_-\|acetyl-CoA-carboxylase-subunit-alpha	gnl\|CDD\|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NZ_CP014961.1\|WP_005098726.1\|1195057_1196695_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|234679	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed.	0
NZ_CP014961.1\|WP_005063407.1\|1216864_1218034_-\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	5.50588e-92
NZ_CP014961.1\|WP_074246520.1\|1210399_1211980_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP014961.1\|WP_052539824.1\|1205129_1205978_-\|LLM-class-F420-dependent-oxidoreductase	gnl\|CDD\|274680	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a domain found in a distinctive subset of bacterial luciferase homologs, found only in F420-biosynthesizing members of the Actinobacteria. [Unknown function, Enzymes of unknown specificity].	2.0751e-81
NZ_CP014961.1\|WP_005063434.1\|1203386_1204289_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NZ_CP014961.1\|WP_005063435.1\|1202181_1203351_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP014961.1\|WP_016893597.1\|1216055_1216841_-\|enoyl-CoA-hydratase-family-protein	gnl\|CDD\|236109	PRK07827, PRK07827, enoyl-CoA hydratase family protein.	2.98633e-140

>NZ_CP014961.1|WP_005116205.1|1206097_1207219_+|dimethyl-sulfone-monooxygenase-SfnG
MTTERISDHVKFAYWVPNVSGGLVTSTIEQRTDWGYDYNVKLARTAEDNGFEYALTQVRYEASYGAEYQHESTSFSLALLLATERLKVIAAVHPGLWQPGVLAKLGATADHLSGGRFAVNVVSGWFKDEFTHLGEPWLEHDERYRRSAEFLQVLRKIWTEDDVDFRGDFYRIHDFTLKPKPLHTPELFQGGNSTAARRNGGLYSDWYFSNGKDFAGITDQIVEVRDHARTVSREVNIALNGFIIARDTEAEARDVLREIVEKANRPAVEGFRAAVQQAGAATGDKKGMWADSSFEDLVQYNDGFRTQLIGTPEQIAERIAAYRRRGVDLILGGFLHFQEEIEYFGAKVLPLVREIEAADSQETLSEYRVPVLS
>NZ_CP014961.1|WP_052539824.1|1205129_1205978_-|LLM-class-F420-dependent-oxidoreductase
MDYGLVLFTSDRGISPAIAAKAAEDGGFSTFYVPEHTHIPVKREAAHPGTGGAELPDDRYMRTLDPWVSLGAACAVTSKIRLATAVAIPVEHDPITLAKSIATLDHMSGGRVTVGVGYGWNTDELADHHVPAGRRRTMLREYIEAMRKLWEDEEASYSGEFVNFGPSWAWPKTVQKHVPVIVGAGGTEKNFTWIAKNADGWMSTPRDEDIAGKIVALKEAWKAAGRDGDPLIYVLAGKPDPEQLAAWRELGVTEAIFGMPDRSEEEVRAYIDRLSGKLAAFA
>NZ_CP014961.1|WP_005063432.1|1204530_1205133_+|hypothetical-protein
MELSFDTSGLVPSEDGWYDPATGDQFWVSHSRGAYLSVPLNDVGAVRRVLVETVLNRPAGVVEAFVVGVDALPGLLYVVKVPKADAPQGLTFMASIVVPRAHSYAMVCGAFAEGPVTGIREATVLEEMLAAGGPSSQMWPPHPYAPDLEPGIPYNIADEMRWDERFPDHPLTRLRRWVARVTPTIRVGRKFAALPPFSVR
>NZ_CP014961.1|WP_005063434.1|1203386_1204289_+|succinate--CoA-ligase-subunit-alpha
MSIFLNKDSKVIVQGITGGEGTKHTALMLKAGTQVVGGVNARKAGTTVSHVDKSGQSVDLPVFGSVAEAIKETGADVSIAFVPPAFSKDAIIEAIDAEIPLLVVITEGIPVQDSAYAWAYNVEKGNKTRIIGPNCPGIITPGEALVGITPNNITGTGPVGLVSKSGTLTYQMMYELRDFGFSTAIGIGGDPVIGTTHIDAIEAFEKDPETKIIVMIGEIGGDAEERAADYIKANVSKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTPSETAKLAREILQSL
>NZ_CP014961.1|WP_005063435.1|1202181_1203351_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MDLFEYQAKELFAKHNVPTTPGRVTTTAEDAKAIAEEIGKPVMIKAQVKVGGRGKAGGVKYAATPDDAFTHAQNILGLDIKGHIVKKILVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGVEIEVTAEENPDALAKVPVDAVKGVDLALAREIAEKGKLPAEVLDSAAVTIQKLWEVFVGEDATLVEVNPLVRTPDNQILALDGKVTLDGNADFRQPGHAEFEDKDATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGENHNGVKPANFLDIGGGASAEVMAAGLDVILGDSQVKSVFVNVFGGITACDAVANGIVGALKTLGDTASKPLVVRLDGNKVEEGRAILAEFNHPLVIQAETMDAGADKAAALAAASN
>NZ_CP014961.1|WP_074246547.1|1200712_1201684_-|M23-family-metallopeptidase
MPIDEFGLSDALERPELEDYDVYEDAPEEGAETEDQTALDQLEQDWEEDTDEADRIRASIEATADWFAASAARTRDPRDTPTDKLPRISSGGVHRRREIGQVGKTRLALAAMAAGAAAAAGYNALSEHDAATAADHHGLALGNSAAVLATHGPQLVSAPLATDASVTDEQLAKATAFATERADREKRLLAPRFVMPTNGTFTSGFGYRWGALHGGIDIANSIGTPIVAAADGVVIATGPTAGYGAWVKIRHSDGTVTLYGHINTWEVSVGQRVMAGDRIATIGNRGNSTGPHLHFEVLLGGSQRIDPQGWLANKGLTFTRFGD
>NZ_CP014961.1|WP_016893591.1|1198185_1200606_+|DNA-helicase-PcrA
MANLSEPALFDMPSDSTASSDALLDGLNPQQRAAVAHQGAPLLIVAGAGSGKTAVLTRRIAYLLAARDVSPGQILAITFTNKAAAEMRERVGRIVANRVQSMWVSTFHSSCVRILRNQASLLPGLNSNFSIYDSDDSRRLLQMIGRDMGLDIKRYSPRLLATAISNLKNELISPEQAVANLTAGGQDGELRGDLPQIVADVYGEYQRRLRAANALDFDDLIGETVAVLQQFPQIAQFYRRKFRHILVDEYQDTNHAQYVLVRELVGAHVDHTVDPDGPEPAELCVVGDADQSIYAFRGATIRNIEEFERDYPNAKTILLEQNYRSTQNILSAANSVIAKNANRREKRLWTDSGEGELIVGYVADNEHDEASFIAREIDGLFDRSDANYGDIAVFYRTNNNSRSLEEIFIRTGIPYKVVGGVRFYERKEIRDIVAYLRVLTNPGDAVSLRRILNTPRRGIGDRAEACVAVHAETNGIGFGEALADAAAGKVAMLNSRSEKAIAAFMDMLDQIRVTLRTDDPGALPDIGDVVEAVLNHTGYRYELENSSDPQELARLDNLNELVSVAHEFSADAANAQAAGEDVPVDDEDVGAPPGSLEAFLERVSLVADADELPESSAGVVTMMTLHTAKGLEFPVVFVTGWEDGMFPHMRALGDPVELAEERRLAYVGITRARQRLYLSRAKVRSSWGQPMMNPESRFLQEIPQELIDWRRTDPLPGRIATGAGSYGGGGYGSGGSRAGGSLGAPSKKRTKPLMVLETGDRVSHDKYGLGRVVEVTGVGESATSLIDFGSEGRVKLMHNFAPVQKL
>NZ_CP014961.1|WP_005063441.1|1197599_1197890_-|chorismate-mutase
MTTHMTEKASQGSGDPTLDIDELRKEIDRLDAEILAAIKRRTEVSREIGKARMASGGPRLVHSREMKVLERYSELGQEGHTLAMLLLRLGRGRLGH
>NZ_CP014961.1|WP_062919454.1|1196737_1197556_-|hypothetical-protein
MSDQDKGDDKPDAEENSTDKPTPKDAKPATADDRSVDYELEAAVAAERTPTGKFVARHATKIVIGVLAVCLAAVTAVAVGLWVENNRTVDDIPQARPTVKLGVPLVNPEVTTSSTTTTTKSRTRTTTSTTTGGTDTSTTSASATTTATTVTSATTTSISVPGPTTTSVPREATKDEQYQLTNVLKAFYAALGAKNLEVLNALSCVKITDEDLEGQADDLKITVDKVEKTVINGDTASSRVTITATAGGKTQTKSGVAGFARISNRWVTCANQ
>NZ_CP014961.1|WP_005098726.1|1195057_1196695_-|glucose-6-phosphate-isomerase
MTLSAAWQALETHHKQIASTHLREFFAEDPARGSELTVTVGDLYIDYSKHRLNRETLALLVDLAKAADLEGRRDAMFAGAHINTSEDRAVLHTALRLPREAQLVVDGQDVVADVHQVLDAMGDFTDRLRSGEWTGATGKPITTVVNIGIGGSDLGPVMVYQALRHYADAGISARFVSNVDPADLVATLADLDPATTLFIVASKTFSTLETLTNATAARRWLVAALGDEAVSKHFVAVSTNAKLVSEFGIDTTNMFGFWDWVGGRYSVDSAIGLSVMAAIGREAFGQFLAGFHIVDEHFRTAPLEQNAPALLGLIGLWYSNFFGAQSRGVLPYSNDLSRFAAYLQQLTMESNGKSVKADGAPVTVDTGDIYWGEPGTNGQHAFYQLLHQGTRLIPADFIGFSEPTDDLPTADGTGSMHDLLMSNFFAQTQVLAFGKTAEEITAEGTAPNVVPHKVMPGNRPSTTILASKLTPSTVGQLIALYEHQVFTAGTVWGIDSFDQWGVELGKKQAIALLPVITDDTSPAQQTDSSTDTLVRYYRNARGRAR
>NZ_CP014961.1|WP_062919456.1|1208442_1209768_+|hypothetical-protein
MNQPSRANPAQARALLTVAFGPSAVALVIIAAIVLVQLVIANSDMTGTFGAVASMWLGTHLVPISIGGRVIEVLPLLPTAAMVWGVARTVASALAPTTSWYVIRWVIASALAGPLLMTAISLAIIHDASTVLTQLQSPNALRAFGCVLGVHSVGAVIGVVMRVGRRIALVLQLPSWPMDAARGAVAGVLALFGLSGAVTAGSLVVHWATMDQLYSVTNDFVGQLSLTLLAILYAPNVILGSCALAVGSSAHVGTATFSAFAVFGGQLPAVPILAAVPTPPLGPAWVALMIIGAASGVAVGQQCARHPVPWPTAIHKVVTAALLAATFLAIVGKLAGGQLGNFGRLGIDQGTFGPGVFFWFLVIGLLTVFMLGGATRLPARTRRDPEPAPEPGPEPTPEPEMEAEPEPEPGPQRDPEPESEPEADPNEAPESDPSDPPEPAK
>NZ_CP014961.1|WP_005126840.1|1209791_1210430_+|phosphoribosylglycinamide-formyltransferase
MSVPSQSVEIAPSAPARVVVLASGTGTLLRSLLDAATGDFPARIVAVGTDRPCPALDIAADAQLPSYTVRLGDYDSRDQWDAAIAEATAVHRPDLVVSAGFMKILGPQFLSQFLGRVINTHPALLPSFPGAHAVPEALAHGVKITGCTVHLVDAGMDTGPILAQQAVPVDRDDDEASLHERIKVVERTLLVDVLAAVATKGLTWNGRRASIK
>NZ_CP014961.1|WP_074246520.1|1210399_1211980_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MERKKGLHQVSTQRPIRRALISVYDKTGLEELASGLHAAGVELVSTGSTAKTIAAASIPVTPVEDVTGFPEVLDGRVKTLHPHVHAGVLADTRREEHLTQLEELGVQGFELVVVNLYPFAATVASGAAEDECVEQIDIGGPSMVRAAAKNHPSVAVVVDPAAYGEVLAAVTAGGFTLEARKVLAAKAFRHTAEYDVAVAGWLSGVAEPGDAELPSWIGGTWNRSAVLRYGENPHQRAALYVGAAGQGLAQAEQLHGKEMSYNNYTDADAAWRAAWDQDKACAAIIKHANPCGIAVSDISIADAHLKAHECDPLSAFGGVIAVNREVSVEMAERVADIFTEVIVAPGYADGAVEVLSRKKNVRLLRAAQPESGSTEWRQISGGLLVQQRDALDAEGDDPANWTLVAGAAADADTLADLVFAWKVGRAVKSNAIVIASGGATIGVGMGQVNRVDAARLAVSRGGDRVSGAVAASDAFFPFPDGLEVLSQAGVRAVVHPGGSMRDELVTDAAKAAGITLYTTGARHFAH
>NZ_CP014961.1|WP_005098875.1|1212002_1213856_+|ABC-transporter-ATP-binding-protein/permease
MVQPSLDWPGEPLRSLVWTLQAWAVTMLVFLAVAVIVARFTQWGQQFWRVNAPFFWGRGTWRTWALLAFVMWHTVYMARVAVIFTYQYKDLMNALQVGSEALVTHDSALLTDARQAFFTSFAISGVLVVLTVTYTVVDLFLRRVFAIRWRVWLNTRLVDDWMSQDAFYRNRFLDPPVENPDQRIQNDIETHTTKSVDLVLGAVNKTLLIVMFTGVLWQLSGPLLLWGFEIPRAMVFIAFVFSITVTVLAFWIGRPLVRLNFLNERYGASFRYALVRLRDSAERVAFYRGGERERRLLHSRFNEIIANMWRIVFAQLRLNGWNRGVGDVTTGMIPYIVQAPRFFAGQIKVGDLLQTVAAFGNVCGAMSFFRDSYDEFTVYRAALLRIDQMLDSDHRARDLPRIAVTDADAALTLTDVGVRNLQGQDMITDLNLALTPGGSVVVKGPSGCGKTTLLRSLAQLWPQTSGLVARPDGWATLFLPQLPYLPLGNLRETVVYPLPVEEVSDEELKQALRDVSLGHLTERLDQEADWAAVLSLGEQQRVSFVRVLLVRPTVVFLDESTSALDEGLEDAMYALVRERLPACVVVSVGHRSTIDRHHQSRLELTGTGGWELVAIPG
>NZ_CP014961.1|WP_062919457.1|1214162_1215413_+|hypothetical-protein
MFVQDPRWRQFVADHAPRYEETVFLPALVPAPSTFTERIAAAVTSATTSGAKGLRLRGFRGSEFDFKLTERLSRTPPTDGQSLTEWLSGAADGRRACVAINDVSSWDLGLAALAQSMVRSLVPDRDLVSGADIYTFVADVEWTPFGIHKDDEPSLIFHLGPGLKELWVWPAGGIGQDQLFENPSLGRVSFDFARLLPGARRYTLRPGDFVCIPQGRYHLFRNAGPSVFLGVTLFPPDVRKSFSGLLLDHFGARLDAADEPRSFDDVRRLVVDTLHDPGALAALSETIDVAAAKQRTAGYLRAPKTAALRIGAPPADAPLVWAYAGVVECVAGADRTHLVARGREIVFGGTVNLDELLALDGEFTLNDLDAVLAPQLDDGDRRRHVVNALWRLGALSLGRAPSSALPTTRAACAASA
>NZ_CP014961.1|WP_005116210.1|1215366_1215969_-|DUF1707-domain-containing-protein
MSNLPERVTASMRAADVDRMRVAQLLSDAAAQGRLELSEFEQRLAKVYSANTYGELDQLSADLPDVATSPVRGQGSKPAPSTVLMAIMSGFERRGRWNVPGKLTSFALWGGGVLDLRYADFTSNEVEIRSFSIMGGQTILLPPEVNVDVRGVAVMGGFDHSASGNGVQGAPHVTVKGFSLWGGVNVKRKRRKRRESLEER
>NZ_CP014961.1|WP_016893597.1|1216055_1216841_-|enoyl-CoA-hydratase-family-protein
MSDTLVQYEVEGRAARLTLDSPHNRNALSSGLVRQLREGLQRAATDKTVRAVVLTHTGNTFCAGADLSESTGASADPQDVAKDRAGQLTALLRDILELPLPVVIAVNGHVRAGGFGLVGAADIAVAGPDSTFALTEARIGVAPSIISLTLLPRLTGRAAGRYFVTGEKFDARVAAEIGLVTKSVDSAEAVEAAVTSLVDDIALGSPQGLAESKRLTTAPILADFDARAVELTETSARLFVSPEAQEGMLAFLQKRPPAWQV
>NZ_CP014961.1|WP_005063407.1|1216864_1218034_-|acyl-CoA/acyl-ACP-dehydrogenase
MTQPNPYVESDERKALRQAVASLATSYGHEYYLEKSKTHEPLAELWDEAGKLGFLGVNIPEEYGGGGAGMYELGLVFEELSAAGCPLLLMVVSPAINATIIARYGTDAQKKSWLPAMAEGSFKMAFAITEPDAGSNSHNIITTAKRDGGDWILNGRKVFISGVNEANAVLVVARTEEAKTGKLKPALFVVPTNTKGFEYTPIDMQLTLPEQQFQVFLDDVRVPGDALVGSEDAALMQLFAGLNPERIMGAASGVGLTRLALNKATEYVKTRQVWKTPIGAHQAIAHPLAEIKVELELAKLMMQKAATLYDCGDDWGAAEAANMAKYAAADVACRAADRAVQSLGGNGLTTEYGVAPLLNLSRFGRIAPVSREMILNFVAQTSLGLPRSY
>NZ_CP014961.1|WP_016893598.1|1218030_1220109_-|acetyl-CoA-carboxylase-subunit-alpha
MTRKESMTVPSITSVLVANRGEIARRVFATCRKLGLGTVAVYSDADADSPHVSEADAAVHLPGTSSAETYLRGELIIAAAKATGADAIHPGYGFLSENADFARAVADAGLTWIGPPVAAIESMGSKIESKKLMDAAGVPVLGQLDPETVTTAQLPVLVKASAGGGGRGMRIVSELDKLPAEIAAAQREAQSAFGDPTVFCERYLGTGRHIEVQVMADAHGTVWAVGERECSIQRRHQKVIEEAPSPLVTRVDGMRERLFEASRTAAAAIGYVGAGTMEFLATEDGEFFFLEMNTRLQVEHPVTECTTGLDLVALQIQVADGGTLPAEPPAIQGHSIEARLYAENPAAGWQPQSGTVRRFDIPGATAEFHLPGHPGRNGVRLDSMIETGAEVEGRRLRGSTVSVHYDPMLAKVITVAPTRIEAARLLASTLERARIHGLTTNRDLLVNVLRHPAFLDGDTDTSFLDKHGLDTLVRPLADEAAHQYSALAAALADAAANRAQAVACAAVPSGWRNLRGPSSGFQTKEFVAGESTLRVRYRLTRTGLELDGASDTAWPAIELVSATPEHVALVIDGVRRGFDVANYGDTVDVDSPLGPVALTVVPRFTDPSTEVAAGSLIAPMPGVVLRLGAAVGDAVTAGTPIVWLEAMKMEHTIVAPADGVVEILNVEPGQQVELGTVLAQLATEATTEGEPA
>NZ_CP014961.1|WP_005063403.1|1220105_1221701_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit
MTVLRTAVNTNSPEYIAAAEAMETKLAEVNAETAKALAGGGPKYVARHHERGKLLARERIELLIDPDSPFLELCPLAAWGSDFTVGASLVTGIGVVEGVECMIVANDPTVKGGTSNPWTLRKVLRANDIAFKNRLPVISLVESGGADLPTQKEVFVPGGQMFRDLTRLSAAGIPTIALVFGNSTAGGAYIPGMSDHVVMIKERSKVFLAGPPLVKMATGEESDDESLGGAEMHSRVSGLGDYLAVDEQDAVRLGRQIVSRLNWVKKGPKPAAVIEPIADQEELIGIVPGDLRIPFDPREVIARIVDGSEFDEFKEQYGSSLVTGWARLHGYPIGILANARGVLFSEEAQKATQFIQLANQTNTPLLFVHNTTGYMVGKEYEEGGMIKHGSMMINAVSNSTVPHLSLIVGASYGAGHYGMCGRAYDPRFLFAWPSAKSAVMGGTQLAGVISIVSRAAAAARGQTVNEEADAAMKAAIEAQIEAESLPMFMSGRLYDDGVIDPRDTRAVLGMCLSAIANGPIEGTSNFGVFRM

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Crispr_ID: NZ_CP014961_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014961_4

5032873-5032967

Orphan

Consensus_repeat	Method
GCCAGCCCGCTGAACCCCAACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014961_4

>merge|NZ_CP014961|4|5032873-5032967|CRISPRCasFinder
GCCAGCCCGCTGAACCCCAACAACCCCGCCAACCCGGCCAGCCCGCTGAACCCGAACAACCCGGCCAATCCCGCCAGCCCGCTGAACCCGAACAA

>NZ_CP014961|4|3|5032873-5032967|CRISPRCasFinder
GCCAGCCCGCTGAACCCCAACAA	CCCCGCCAACCCGGCCAGCCCGCTGAACCCGAACAACCCGGCCAATCCC
GCCAGCCCGCTGAACCCGAACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014961.1\|WP_005105816.1\|5039245_5040499_+\|NADH:flavin-oxidoreductase/NADH-oxidase-family-protein	unknown	unknown	gnl\|CDD\|240084
NZ_CP014961.1\|WP_017205868.1\|5023471_5024593_+\|bifunctional-2-methylcitrate-synthase/citrate-synthase	unknown	unknown	gnl\|CDD\|237590
NZ_CP014961.1\|WP_005103161.1\|5033029_5034127_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274934
NZ_CP014961.1\|WP_074292112.1\|5040429_5040912_+\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|281995
NZ_CP014961.1\|WP_005101757.1\|5034853_5035702_+\|DUF2510-domain-containing-protein	unknown	unknown	gnl\|CDD\|376704
NZ_CP014961.1\|WP_005071725.1\|5027187_5029458_-\|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|235367
NZ_CP014961.1\|WP_005138247.1\|5022557_5023475_+\|methylisocitrate-lyase	unknown	unknown	gnl\|CDD\|131370
NZ_CP014961.1\|WP_005138254.1\|5037462_5038536_+\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|226326
NZ_CP014961.1\|WP_005063839.1\|5038532_5039123_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP014961.1\|WP_005120026.1\|5040977_5042042_+\|galactose-1-phosphate-uridylyltransferase	unknown	unknown	gnl\|CDD\|238341
NZ_CP014961.1\|WP_025982628.1\|5021055_5022561_+\|MmgE/PrpD-family-protein	unknown	unknown	gnl\|CDD\|224990
NZ_CP014961.1\|WP_062920170.1\|5030949_5032539_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|235731
NZ_CP014961.1\|WP_016343627.1\|5035706_5036567_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224332
NZ_CP014961.1\|WP_005071727.1\|5029894_5030314_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NZ_CP014961.1\|WP_005071735.1\|5036658_5037450_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181131
NZ_CP014961.1\|WP_005063818.1\|5019516_5020938_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226322
NZ_CP014961.1\|WP_005071732.1\|5034178_5034844_+\|glyoxalase	unknown	unknown	gnl\|CDD\|372667
NZ_CP014961.1\|WP_005071723.1\|5026181_5027069_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_079262855.1\|5024664_5025345_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014961.1\|WP_005063830.1\|5030303_5030906_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP014961.1\|WP_005105816.1\|5039245_5040499_+\|NADH:flavin-oxidoreductase/NADH-oxidase-family-protein	gnl\|CDD\|240084	cd04733, OYE_like_2_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 2. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	8.91091e-165
NZ_CP014961.1\|WP_017205868.1\|5023471_5024593_+\|bifunctional-2-methylcitrate-synthase/citrate-synthase	gnl\|CDD\|237590	PRK14033, PRK14033, bifunctional 2-methylcitrate synthase/citrate synthase.	0
NZ_CP014961.1\|WP_005103161.1\|5033029_5034127_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274934	TIGR04036, family_protein, putative luciferase-like monooxygenase, FMN-dependent, CE1758 family. This tightly conserved subfamily of the bacterial luciferase-like monooxygenase (LLM) family, with members showing > 60 % pairwise sequence identity, includes proteins from both species with and species without the ability to make coenzyme F420. Therefore, the like cofactor is FMN rather than F420. The presence of three members in Kineococcus radiotolerans SRS30216 and two in Saccharopolyspora erythraea NRRL 2338 suggest closely related (subfamily) rather than exactly conserved (equivalog) function. Gene neighborhoods around members are not conserved. [Unknown function, Enzymes of unknown specificity].	2.09098e-76
NZ_CP014961.1\|WP_074292112.1\|5040429_5040912_+\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl\|CDD\|281995	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase. This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.	4.00501e-11
NZ_CP014961.1\|WP_005101757.1\|5034853_5035702_+\|DUF2510-domain-containing-protein	gnl\|CDD\|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	2.65198e-41
NZ_CP014961.1\|WP_005138247.1\|5022557_5023475_+\|methylisocitrate-lyase	gnl\|CDD\|131370	TIGR02317, Methylisocitrate_lyase, methylisocitrate lyase. Members of this family are methylisocitrate lyase, also called (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase. This enzyme acts in propionate metabolism. It cleaves a carbon-carbon bond to convert 2-methylisocitrate to pyruvate plus succinate. Some members of this family have been annotated, incorrectly it seems, as the related protein carboxyphosphoenolpyruvate phosphomutase, which is involved in synthesizing the antibiotic bialaphos in Streptomyces hygroscopicus.	1.72028e-143
NZ_CP014961.1\|WP_005138254.1\|5037462_5038536_+\|diacylglycerol-kinase	gnl\|CDD\|226326	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown].	4.32106e-115
NZ_CP014961.1\|WP_005063839.1\|5038532_5039123_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.72256e-07
NZ_CP014961.1\|WP_005120026.1\|5040977_5042042_+\|galactose-1-phosphate-uridylyltransferase	gnl\|CDD\|238341	cd00608, GalT, Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme contains two identical subunits. It also demonstrates that the active site is formed by amino acid residues from both subunits of the dimer.	1.66003e-113
NZ_CP014961.1\|WP_025982628.1\|5021055_5022561_+\|MmgE/PrpD-family-protein	gnl\|CDD\|224990	COG2079, PrpD, Uncharacterized protein involved in propionate catabolism [General function prediction only].	3.70942e-146
NZ_CP014961.1\|WP_062920170.1\|5030949_5032539_-\|AMP-binding-protein	gnl\|CDD\|235731	PRK06188, PRK06188, acyl-CoA synthetase; Validated.	0
NZ_CP014961.1\|WP_016343627.1\|5035706_5036567_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	1.90611e-09
NZ_CP014961.1\|WP_005071727.1\|5029894_5030314_+\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	2.31723e-22
NZ_CP014961.1\|WP_005063818.1\|5019516_5020938_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|226322	COG3800, COG3800, Predicted transcriptional regulator [General function prediction only].	2.25337e-158
NZ_CP014961.1\|WP_005071732.1\|5034178_5034844_+\|glyoxalase	gnl\|CDD\|372667	pfam13669, Glyoxalase_4, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	1.98773e-08
NZ_CP014961.1\|WP_005071725.1\|5027187_5029458_-\|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	gnl\|CDD\|235367	PRK05222, PRK05222, 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional.	0
NZ_CP014961.1\|WP_005071735.1\|5036658_5037450_+\|SDR-family-oxidoreductase	gnl\|CDD\|181131	PRK07814, PRK07814, SDR family oxidoreductase.	1.62564e-153
NZ_CP014961.1\|WP_005063830.1\|5030303_5030906_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.63043e-07

>NZ_CP014961.1|WP_062920170.1|5030949_5032539_-|AMP-binding-protein
MPDPFDPLHGSINSGHLLVSALKRNRDAPALVLGDVTLTGAQMADEISKYIQAFIELVPDPTDGQGMLALNRPEVLLVIGAGQLLGTRRTALHPLGSLDDHAYVLADAKITTLVIDPTPQFVERAAALVAKVPTLTRVLTLGPVPVELAEVGQDLVAAAAGFAARPLTPINLSPDHINGLTYTGGTTGKPKGVIGTSQSILTMTQIQLAEWEWPERPKFLMCTPLSHAGAAFFMPTLMKGGSMVVLPKFDAGAVLAAIEEHQITATMLVPSMIYALLDHPDSRTRDLSSLQTVYYGASAINPVRLAEAIERFGPIFAQYFGQSEAPMVISYLAKGDHDAKRLSSCGRPSAFLRTALLDENDRPVKQGEPGEICVGGPLVAGGYWGLPEQTAETFKNGWLRTGDVAREDEDGFWFIVDRTKDMIVTGGFNVFPREVEDVVAEHPSVAQVGVIGVPDEKWGEAVTAIVVLRSDASSDEEAVALMTSEIQSAVKERKGSVQSPKHVIVADSLPLTALGKLDKKALRQKYTTV
>NZ_CP014961.1|WP_005063830.1|5030303_5030906_+|TetR/AcrR-family-transcriptional-regulator
MGRKPQYSADDILDAALGLVAAGGPSAATATAIGRVLGAPSGSIYHRFPSRDELMARLWLRSIARYQDGVLAALALPDADDALAAAIDHAFDWTASNHNEALLLLQYEKADLVAHWPDTLATELKTLNSRVRKTLREYTDRRYGEVTTERIDKVMFALIDMPYAAVRRHLPDKGEPAPWLREFVHASAHALLARACPNKP
>NZ_CP014961.1|WP_005071727.1|5029894_5030314_+|PaaI-family-thioesterase
MITLDQAQQVLDAQPFSRLLGAAITRVDERGIQLSLQIRDELRQQSGFIHGGVLSYLADNAITYACGLGLGADIVTSGYTIEYVAPARDGARLVADASLVSAGRTKALGRCEISVEDHDGTATLVAVAQGTSMVRRSGT
>NZ_CP014961.1|WP_005071725.1|5027187_5029458_-|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase
MTTQPLKATTLGSARIGPRRELKRATESYWAGRISRVELEDVAAGLRRDNWTALAAAGLDSVPVNTFSYYDQVLDTAVLLGALPPRVAGIADDLDRYFAAARGNTDVTPLEMTKWFDTNYHYLVPEIGPDTQFTLNPAKLFGELKEAQALDVPARPVVVGPITFLALSKSVDGASAPIERLDEVVALYEQLLVQLAEAGVGWVQIDEPVLVTDILPNGPELAERVYGRLGTVADRPAILVASYFGELGAALPALARTPIEAIAVDLVYGSASAVASVPELAGKTLVAGVVDGRNIWRTNLQSALGTLASLLGSAESVAVSTSCSTLHVPYSLEPETELDDQLRSWLAFADEKVKEVVVLARALGEGRDAVAAEIAASNAAAESRRTDPRLNNGQIRTRLDAVLADGVSRGDAAERRRRQDERLRLPALPTTTIGSFPQTVEIRKARQALTRGEIDDVEYVRQMRAEVADVIALQEKLGLDVLVHGEPERNDMVQYFAEQLDGFFATQNGWVQSYGSRCVRPPILYGDVARRKPMTVEWATYAQSLTQKHVKGMLTGPVTILAWSFVRDDQPLGDTANQIALAIRDETVDLQNAGIAIIQVDEPALRELLPLRNSEKQAYLDWAVGAFRLSTSGVSDATQIHTHLCYSEFGEVIGAIADLDADVTSIEAARSHMEVLDDLNAIGFSNSVGPGVYDIHSPRVPSTEEMATSLREALKAVPAQRLWVNPDCGLKTRKVDEVTSSLANLVAAAASVRADA
>NZ_CP014961.1|WP_005071723.1|5026181_5027069_-|hypothetical-protein
MNTVALEMVPPNVDGGLDRAADELRKLRQFSAEFGIDRRIAHVMIPSMIVEDGDRPLEMKPKLDVVDYWSIIRAELPAVRGLCTQVTSFSDETSLRGRLTDLTDAGMDGVIFVGVPRTMNDGDGAGIPPTDALSKFDDIVQNRGAILIPTRAGEQGRFSFKCDKGANFAMTQLLYSDAVVGFLHEFAHTSDHRPEVLLSFGFVPKLESKIGLIDWLIQDPGNEAVAREQDFVKALAAREPGERRPQLVDLYKRVVDGVAGLGFPLSIHFEAPYGLARPAFETFAEMLEYWSPAVS
>NZ_CP014961.1|WP_079262855.1|5024664_5025345_-|hypothetical-protein
MASAAAVDWDEGSEIIRFPYGCAGWDPALGDPAQRLVTLWATWHKGQNWPRLLGVVEELYDVSAVSYRDESDCIRCRPSSFQYRSVELATRWPEESSRGEPGRRVITGCVVGLRVISVVEPADADIQARQEERDRARRTLDLFGPPGVFGAVIPSRGDRVTVDLADPRLSVNDTRGYAGVVTGIAGQVSRAVHSPDGFYTGLLDINSEAPPPDELFIQLLCDRKPE
>NZ_CP014961.1|WP_017205868.1|5023471_5024593_+|bifunctional-2-methylcitrate-synthase/citrate-synthase
MTISTPTIHKGLAGVVVDTTAISKVVPETNSLTYRGYPVQDLAVQCSFEQVAYLLWHGELPNEGELALFNQRERAQRRLDRSLMALLAKLPETCHPMDVVRTAISYLGAEDPSEDDNTPDANYAKSLRMFAVLPTIVASDMRRRRGLDPIQPHSHLGYSANFLRMCFGEIPDPAIVKAFEQSMILYAEHSFNASTFAARVVTSTQSDIYSAVTAAIGALKGSLHGGANEAVMHDMIEIGDASKASEWLQSKRSRKEKIMGFGHRVYKNGDSRVPTMRAALEDVARARDGGQWLEIYKVLESEMDAATGIKPNLDFPTGPAYYLMGFDIPCFTPIFVMSRITGWTAHIMEQAAANALIRPLSEYSGKPQRTLAC
>NZ_CP014961.1|WP_005138247.1|5022557_5023475_+|methylisocitrate-lyase
MSTLLASATDAATKRAAFRQGLSSGELLRLPGAFSPLVAKLIEEIGFEGVYVSGAVLSADLALPDIGLTTLTEVSARGRQIASVTDLPTLIDADTGFGEPMSAARTVAVLEDSGVAGLHLEDQVNPKRCGHLDGKAVVETAEMVRRLHAAVSARRDPNFVICARTDAAGIEGLPAAIDRARAYADAGADLIFTEALTDIGEFEKFRAAVDIPLLANMTEFGKSELVTADRLREVGYNVVIYPVTTLRLAMYAVEQGLHEINSAGTQSGLLEQMQHRSRLYELLHYAEYNRFDTEIFNFSLDGGQQ
>NZ_CP014961.1|WP_025982628.1|5021055_5022561_+|MmgE/PrpD-family-protein
MHVHSVRTRRSAEAFPRDQHLAWKIAEIASDPVAVPADTAAMVINRVIDNAAVSAASVIRRPVTVARRQAQAHPAAPGAHVFGIGGGYSAEWAAWANGVAVRELDFHDTFLAADYSHPGDNIPPLVAVAQQLGIGGDDLIRGLATAYETQINLTRGICLHEHKIDHVAHLGPAVAAGLGTMLKLDTETIYQAIGQALHLTTATRQSRKGLISSWKAYAPAWAGKVAIEAVDRAMRGEGAPSPIWEGEDGVIAWLLGGPEKLYEVPLPGPGEEKRAILDSYTKEHSAEYQSQAPIDLARRMRERIGDLEQIATIVLHTSHHTHVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALEDGTWHHERSYAPERAHRPETIELWNKISTIEDPEWTRRYHSTDPDEKAFGCKAVVTLKNGEVIADELAIADAHPLGARPFARDNYVNKFTVLSDGVIAPREQERFLSVAQGLADLKPGSLGALNPLVDAVVLDKAPTTPEGIFK
>NZ_CP014961.1|WP_005063818.1|5019516_5020938_-|helix-turn-helix-transcriptional-regulator
MSRPFAGARLRRLREERGLTQAALARVLDLSTSYVNQLENDTRPVTVAVLLRLTERFDLSPHYFSPDSDARLVADLGEIFTEAAVGEVSDLQLEELVARMPSVGQTLVGMHRRLRDVTAELESYRATENAETIGDSVREPLRPMPFEEVRDFFYDHKNYLGELDTAAEDLFEHYGLHVGGLDIQLATVLKQDLGIAVAVDKAGAPSDSSKRRFDAAAGVLRIAHWLTPGQRAFQMATQLALVTQTETMAAILAGADQLSPEAIGVARIGLANYFAGAFLLPYKQFHHAAESSRYDVDILARQFEVGHETVCHRLSTLQRPSMRGVPFILVRTDRAGNISKRQSATAFHFSRVGGNCPLWVVHEAFSNPGQFVTQVAEMPDGRTYFWVARTSSTSTGGFLSTPKSFAIGLGCDIAHAHRLVYSTGIAIDDPSTAVPIGPGCKVCVRESCAQRAFPYIGRSVHVDEDASSGLPYT
>NZ_CP014961.1|WP_005103161.1|5033029_5034127_-|LLM-class-flavin-dependent-oxidoreductase
MRFQLLDIVFHLPNPATRALAPAAERLNRVIETAVLAENLGFDSFAVGERHAGDVLSSAPTVLLGAVAAATDRILLSTGVTVLSLLDPVRAAEDFATIDQLSRGRLEIVIGKGNEDRQYPLMGLDIAKQYEYLQENYELLRRLLREEHVDWVGAHRHPLADATTLPRPYDGPFRIWHGSATSTFAVELAAKWGDPIVTANALQPKENYRVLIDRYRELYAHHGHDPAQLYVGAGSGGLYLADTTEQAIAQYRPIYEARLAQMAKLKAHPQAVGKFPSFESIEDAADRGPVLAGSPERVAEKILDWHEAFGHEFQSISLSPEADFEEQKDTLRRFAEEVVPLVRAEVKSTLWGPLDTRRAKGFTAV
>NZ_CP014961.1|WP_005071732.1|5034178_5034844_+|glyoxalase
MITELDSVLLDVPNLGEAKAAYSRLFNSSAPHPQLHLGLPEWASHPGMLFRVDHLDCAARTVARRGLALTVHGDLATGASNGVTLGLSGQPPAAPQPDADSCRIDHLVLFSPNRDRIIATLCGRLGFDLRLDRLQSWGAHQLFFRGAGLVVEVVLRDDDPSGPDSLWGIAWRTADIEASHARLSGAGATLGDIRNGHKPGTRVVTVKDPALAVPTILIEQR
>NZ_CP014961.1|WP_005101757.1|5034853_5035702_+|DUF2510-domain-containing-protein
MTTPNSGSWQPDPDGRYEFRWHDGQRWTDQVAHQGSVSTAPLGGAATQPAAPDQPAGNQFSGISGDLVDGRFSENEAKPISNQNAKLLRVRLGEPFLARQGSMVAYQGNVDFAFEGGGAAKFLKKALTGEGLPLMRCSGQGDVFLAERAFDVHLLNLNNAGLSISGKNVLAFSAGLNWNIERVRGASVVTGGLFNTTLRGTGWVALTTDGPPVVLNAAEAPTFADTNAVVAWSSNLQTQLKTSFKAGALIGRGSGEALQVSFQGQGFVIVQPSEGIPVVTAG
>NZ_CP014961.1|WP_016343627.1|5035706_5036567_-|helix-turn-helix-domain-containing-protein
MPASSPPTARVVRIVEMLAAAMQPKTVSEIAASTGISRATATAVVNELEAAGWVARDDELRYRIGASLPRAVDTSMPREAQQLLARIAAEAQAGVTVSCISAKALTVVAKAQAGRRAVTGFAVGQSIPLAFPAGSAVMPWRAAEEREQWLGTAAGLSARSGQRLLQQVSDCGYVVYRPDHDDTGMVDLLSDLLGSVGSEVMEAALRERLLRQLSRLTSRPYSPDELTSDEVLPISYLAAPIFDGAEARYELQLGPLLPRATRVVREALIATLMRGARELSGVLGDR
>NZ_CP014961.1|WP_005071735.1|5036658_5037450_+|SDR-family-oxidoreductase
MILDRFKLDGNVAVVTGAGRGLGAAIAEAFAQAGADVLIASRTESQLREVAEKVQAAGRQAEVVVADLSDTEASAALAQKAVDRFGRLDVVVNNVGGTMPKPFLDTTNDDLAEAFSFNVLSGHALLRAAVPHLLKSDNASVINITSTMGRLPGRAFLGYCTAKGALAHYTRTAAMDLSPRIRVNGIAPGSILTSALEVVAGNDEMRNTLEQNTPLHRLGDPDDIAAAAVYLASPAGSFLTGKVLEIDGGLIAPNLDIPLPDLA
>NZ_CP014961.1|WP_005138254.1|5037462_5038536_+|diacylglycerol-kinase
MTKTRVAVWGTGNVGQHALAGVITDPSMELVGVWVSGSNKAGKDAGALAGLDILTGITATTDAAQILALRPDCVVYTAMTDNRLMEALKDLTDLLSAGINVAASAPVFLQYPWGVLPENMLTPIENAAREGNSSIFVGGIDPGFANDLLPLALMGTCQRIDQVRCIEIVDYATYDSATVMFDVMGFGKPMEETPMLLQPGVLSLAWGSVVRQLAAGLGVELDEVTEAYEKLPAPEDFDISSGHIPAGTMAALHFEVRGIKDGRAVTVLEHFTRLREDLAPNWPQPAHEGGTYRVQITGEPSYLLDLGSFSARGDHNYANLIATAMRVVNAVPAVVAAEAGIRTTLDLPLITGKGRAV
>NZ_CP014961.1|WP_005063839.1|5038532_5039123_-|TetR/AcrR-family-transcriptional-regulator
MSARDTLIASVTGLVRRRGVAGTGLNALLEDSGVSRRTIYLNFPGGKQELVAEATRLAGNELTAIIKAAGDDVDPARGIQLFIELWKAQLAETEMQAGCPVVAAVLGRTEAPEAAAVAADAFESWRKILIDRLARYDVDGETARSLASTMIAAIEGAVIMSIAAQSTEALDDVGQRLVELVRLYVPAGAKPNPHVD
>NZ_CP014961.1|WP_005105816.1|5039245_5040499_+|NADH:flavin-oxidoreductase/NADH-oxidase-family-protein
MPDIHDPLPLANGQVLRNRLMKSALSEALGNAEQGPDHRLVQLFSRWGAGGYGLIVTGNVMVDHNHLGEPGNVVIEDDRHLEGLSRWAKATKDGGGLIWMQVNHPGRQANPLVTKHQPVAPSAVRMSVPGWQAPRELTDVEIEDIIDRYARTAVVADTAGFDGVQIHGAHGYLVAQFLSPNTNRRTDRWGGDAQRRMRFVLEIVRRTKAAVSPGFAVAIKLNSADFQRGGFTEEESRGVIAALAAEGIDLIEISGGTYESPAMEGRPVVVSTSTQAREAYFLEYATTARAVAGDVPLAVTGGFRTTAAMNEAIESGACDVIGLGRPTTVNPEAAIELLSTRRDRLTVPDAALPLPARLAATARAKAFLSAHELQWHGTQMHRLGAGSDPDPSIGPWITALRLLKNNGVEAFRKRRSS
>NZ_CP014961.1|WP_074292112.1|5040429_5040912_+|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MDHGLAAPQEQRRRSIPKKEKFMTDKTLRKFRRERAMGRYLLNPAVGALAKLGVRTALASELETTGRRTGQLRRVPVSVQFDSTGAWVICQHGTRSGWGSNIAANPNVRIRQGNRWRTGTAQFRPDDDVVARGRGFGVIGARVVKALETTPISVRIDFTD
>NZ_CP014961.1|WP_005120026.1|5040977_5042042_+|galactose-1-phosphate-uridylyltransferase
MWRTRRELADGREILYFDSTPTERAAVDRRDLPPVSTQSQIRFDPLLGDWVTLASHRQTRTFLPPTDLCPLCPSTPERPTEIPEHAYEVVAFENRFPSLSLHAQAATPPAGAGFGRCEVLCFTSEHDTSFAQLEPRRARLIVDVWAERTKELSAIDGVKQVYCFENHGEEIGVTLAHPHGQIYAYPFITAKTARVLSNVDTHRKQHGTNLFGEILAAERATGTRVVTANDEWTAFVPSFARWPYEVSLYPHRQVADIPDLDDAARSAFAELYLDVLQRFACRFDNPMPYIAGWNQAPTVASGAIRDNWWLHLQVFSIRRAPGKLKYLAGSESGMGAFISDTTPEQVAAELRDVM

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP014961_1	1.1\|709403\|78\|NZ_CP014961\|CRISPRCasFinder	709403-709480	78	NZ_CP014961.1	709346-709423	18	0.769

1. spacer 1.1|709403|78|NZ_CP014961|CRISPRCasFinder matches to position: 709346-709423, mismatch: 18, identity: 0.769

gggtggggtcctgatggtcctccacctcaggggtgggctccgagcgggccggctcagggg	CRISPR spacer
gggtggggtcctgatggtcctccacctcaggggtgggctccgagcgggccggctcagggg	Protospacer
************************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014961_2	2.1\|1107207\|26\|NZ_CP014961\|CRISPRCasFinder	1107207-1107232	26	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	418376-418401	5	0.808
NZ_CP014961_2	2.1\|1107207\|26\|NZ_CP014961\|CRISPRCasFinder	1107207-1107232	26	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	678153-678178	5	0.808
NZ_CP014961_2	2.1\|1107207\|26\|NZ_CP014961\|CRISPRCasFinder	1107207-1107232	26	NZ_CP029333	Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence	54049-54074	6	0.769
NZ_CP014961_2	2.1\|1107207\|26\|NZ_CP014961\|CRISPRCasFinder	1107207-1107232	26	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	143457-143482	6	0.769
NZ_CP014961_3	3.2\|1208104\|31\|NZ_CP014961\|PILER-CR	1208104-1208134	31	NZ_LT984809	Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence	307564-307594	7	0.774
NZ_CP014961_3	3.2\|1208104\|31\|NZ_CP014961\|PILER-CR	1208104-1208134	31	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	249298-249328	7	0.774
NZ_CP014961_3	3.2\|1208104\|31\|NZ_CP014961\|PILER-CR	1208104-1208134	31	NZ_AP018829	Asticcacaulis excentricus strain M6 plasmid pASEM-1, complete sequence	67692-67722	8	0.742
NZ_CP014961_3	3.2\|1208104\|31\|NZ_CP014961\|PILER-CR	1208104-1208134	31	NZ_CP009803	Streptomyces sp. FR-008 plasmid pSSFR1, complete sequence	5442-5472	9	0.71
NZ_CP014961_3	3.2\|1208104\|31\|NZ_CP014961\|PILER-CR	1208104-1208134	31	NZ_CP030354	Novosphingobium sp. P6W plasmid pP6W1, complete sequence	312363-312393	9	0.71
NZ_CP014961_3	3.2\|1208104\|31\|NZ_CP014961\|PILER-CR	1208104-1208134	31	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	300992-301022	10	0.677
NZ_CP014961_3	3.2\|1208104\|31\|NZ_CP014961\|PILER-CR	1208104-1208134	31	NC_023286	Streptomyces sp. F12 plasmid pFRL6, complete sequence	187281-187311	10	0.677
NZ_CP014961_3	3.2\|1208104\|31\|NZ_CP014961\|PILER-CR	1208104-1208134	31	NC_023283	Streptomyces sp. FR1 plasmid pFRL3, complete sequence	254464-254494	10	0.677

1. spacer 2.1|1107207|26|NZ_CP014961|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 5, identity: 0.808

aaccccggccagggtggttggggcca	CRISPR spacer
gaccccggccagggtggtcgcggcgg	Protospacer
.*****************.* *** .

2. spacer 2.1|1107207|26|NZ_CP014961|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 5, identity: 0.808

aaccccggccagggtggttggggcca	CRISPR spacer
gaccccggccagggtggtcgcggcgg	Protospacer
.*****************.* *** .

3. spacer 2.1|1107207|26|NZ_CP014961|CRISPRCasFinder matches to NZ_CP029333 (Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence) position: , mismatch: 6, identity: 0.769

aaccccggccagggtggttggggcca	CRISPR spacer
ttgcccggcgagggtggttggggcac	Protospacer
   ****** **************

4. spacer 2.1|1107207|26|NZ_CP014961|CRISPRCasFinder matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 6, identity: 0.769

aaccccggccagggtggttggggcca	CRISPR spacer
ttgcccggcgagggtggttggggcac	Protospacer
   ****** **************

5. spacer 3.2|1208104|31|NZ_CP014961|PILER-CR matches to NZ_LT984809 (Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence) position: , mismatch: 7, identity: 0.774

gtctgctccggcggctccgccttcgtacggt	CRISPR spacer
atctgctccggcgtcaccgccttcgccccgg	Protospacer
.************ * *********. * *

6. spacer 3.2|1208104|31|NZ_CP014961|PILER-CR matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 7, identity: 0.774

gtctgctccggcggctccgccttcgtacggt-	CRISPR spacer
atcggctccggcgcctccgccttcac-cgctc	Protospacer
.** ********* **********.. ** *

7. spacer 3.2|1208104|31|NZ_CP014961|PILER-CR matches to NZ_AP018829 (Asticcacaulis excentricus strain M6 plasmid pASEM-1, complete sequence) position: , mismatch: 8, identity: 0.742

gtctgctccggcggctccgccttcgtacggt	CRISPR spacer
tgcccctccgccggctccgccgtcgtaccgg	Protospacer
  *. ***** ********** ****** *

8. spacer 3.2|1208104|31|NZ_CP014961|PILER-CR matches to NZ_CP009803 (Streptomyces sp. FR-008 plasmid pSSFR1, complete sequence) position: , mismatch: 9, identity: 0.71

gtctgctccggcggctccgccttcgtacggt	CRISPR spacer
atcggctccggcgcctccgccttcacagccc	Protospacer
.** ********* **********..*   .

9. spacer 3.2|1208104|31|NZ_CP014961|PILER-CR matches to NZ_CP030354 (Novosphingobium sp. P6W plasmid pP6W1, complete sequence) position: , mismatch: 9, identity: 0.71

gtctgctccggcggctccgccttcgtacggt	CRISPR spacer
ctctgcaccggcggcttcgccttcaacgaga	Protospacer
 ***** *********.*******.   .*

10. spacer 3.2|1208104|31|NZ_CP014961|PILER-CR matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 10, identity: 0.677

gtctgctccggcggctccgccttcgtacggt	CRISPR spacer
atcggctccggcgcctccgccttcaccgccc	Protospacer
.** ********* **********..    .

11. spacer 3.2|1208104|31|NZ_CP014961|PILER-CR matches to NC_023286 (Streptomyces sp. F12 plasmid pFRL6, complete sequence) position: , mismatch: 10, identity: 0.677

gtctgctccggcggctccgccttcgtacggt	CRISPR spacer
atcggctccggcgcctccgccttcaccgccc	Protospacer
.** ********* **********..    .

12. spacer 3.2|1208104|31|NZ_CP014961|PILER-CR matches to NC_023283 (Streptomyces sp. FR1 plasmid pFRL3, complete sequence) position: , mismatch: 10, identity: 0.677

gtctgctccggcggctccgccttcgtacggt	CRISPR spacer
atcggctccggcgcctccgccttcaccgccc	Protospacer
.** ********* **********..    .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

225226 : 260878

Mycobacterium_phage(70.97%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005065238.1\|225226_227110_-	SufS family cysteine desulfurase	Q2XUY6	environmental_halophage	5.6e-95	41.7
WP_005063052.1\|227096_228020_-	hypothetical protein	A0A2K9L2D2	Tupanvirus	3.5e-42	36.8
WP_062919159.1\|228437_229709_+	TQXA domain-containing protein	NA	NA	NA	NA
WP_005065241.1\|229705_230749_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	3.8e-16	26.7
WP_074303599.1\|231060_231363_-	helix-turn-helix transcriptional regulator	A0A142F2H9	Mycobacterium_phage	4.1e-32	69.6
WP_052536770.1\|231525_231759_+	helix-turn-helix domain-containing protein	W8ED09	Mycobacterium_phage	1.7e-06	42.1
WP_062919160.1\|231755_232655_+	hypothetical protein	NA	NA	NA	NA
WP_062869300.1\|232675_233539_+	hypothetical protein	A0A142F2J1	Mycobacterium_phage	2.4e-45	39.3
WP_062919161.1\|233635_233992_+	hypothetical protein	R4TPB7	Mycobacterium_phage	2.8e-16	45.3
WP_153995373.1\|234023_234173_+	hypothetical protein	NA	NA	NA	NA
WP_079767737.1\|234605_235649_+	hypothetical protein	A0A068F3L1	Mycobacterium_phage	4.0e-42	46.9
WP_052621499.1\|235645_235900_+	hypothetical protein	NA	NA	NA	NA
WP_062869312.1\|235896_236682_+	sigma-70 family RNA polymerase sigma factor	A0A142F2I6	Mycobacterium_phage	6.7e-42	38.1
WP_062869314.1\|236678_236891_+	hypothetical protein	NA	NA	NA	NA
WP_062919166.1\|237416_237674_+	hypothetical protein	NA	NA	NA	NA
WP_062919167.1\|237670_238570_+	recE	A0A076GDU3	Mycobacterium_phage	4.9e-81	51.0
WP_062919168.1\|238566_239784_+	hypothetical protein	A0A2P1CGD3	Mycobacterium_phage	8.9e-94	50.9
WP_062919169.1\|239788_240676_+	hypothetical protein	A0A0M4RAA7	Mycobacterium_phage	2.9e-86	54.2
WP_052536756.1\|240702_241068_+	hypothetical protein	A0A1P8D5Q7	Corynebacterium_phage	6.1e-14	44.2
WP_062919170.1\|241071_241896_+	DUF2303 family protein	A0A1P8D5Q0	Corynebacterium_phage	6.2e-30	31.8
WP_052536754.1\|241892_242294_+	hypothetical protein	NA	NA	NA	NA
WP_062919171.1\|242290_242569_+	hypothetical protein	NA	NA	NA	NA
WP_062919172.1\|242568_242865_+	hypothetical protein	A0A2D1GGE9	Gordonia_phage	1.9e-05	52.9
WP_062919173.1\|242861_243206_+	hypothetical protein	NA	NA	NA	NA
WP_079767873.1\|243850_244243_+	hypothetical protein	A0A059VL25	Mycobacterium_phage	8.8e-27	52.5
WP_062919174.1\|244239_244704_+	hypothetical protein	NA	NA	NA	NA
WP_153995374.1\|244706_244910_+	hypothetical protein	NA	NA	NA	NA
WP_062919176.1\|244912_245956_+	phage Gp37/Gp68 family protein	A0A142K7I8	Mycobacterium_phage	1.3e-112	57.8
WP_062919177.1\|245952_246588_+	hypothetical protein	A0A142F2L8	Mycobacterium_phage	7.3e-55	51.1
WP_153995375.1\|246584_246938_+	hypothetical protein	NA	NA	NA	NA
WP_052536743.1\|246934_247351_+	hypothetical protein	NA	NA	NA	NA
WP_079767738.1\|247347_248082_+	hypothetical protein	A0A222YVB7	Mycobacterium_phage	1.4e-73	56.2
WP_062919180.1\|248084_248462_+	DUF4326 domain-containing protein	A0A222ZJK9	Mycobacterium_phage	1.1e-21	50.0
WP_062919181.1\|248464_249409_+	hypothetical protein	A0A2H4JEK9	uncultured_Caudovirales_phage	4.9e-47	64.1
WP_062919182.1\|249405_249612_+	hypothetical protein	NA	NA	NA	NA
WP_065211448.1\|249611_250004_+	hypothetical protein	NA	NA	NA	NA
WP_052536737.1\|249993_250311_+	hypothetical protein	A0A142F2L5	Mycobacterium_phage	1.5e-05	38.2
WP_153995376.1\|250307_250916_+	hypothetical protein	NA	NA	NA	NA
WP_052536735.1\|250912_251365_+	hypothetical protein	A0A142F2M2	Mycobacterium_phage	1.9e-12	34.6
WP_052536734.1\|251663_252701_+	hypothetical protein	A0A142F2M4	Mycobacterium_phage	2.3e-58	40.1
WP_052536733.1\|252697_253051_+	hypothetical protein	NA	NA	NA	NA
WP_062919186.1\|253135_253561_+	hypothetical protein	A0A142F2N4	Mycobacterium_phage	3.2e-38	59.0
WP_052536731.1\|253557_253902_+	hypothetical protein	NA	NA	NA	NA
WP_062919187.1\|253898_254336_+	hypothetical protein	NA	NA	NA	NA
WP_153995366.1\|254332_254494_-	hypothetical protein	NA	NA	NA	NA
WP_131804549.1\|254498_254693_-	hypothetical protein	NA	NA	NA	NA
WP_074303556.1\|254698_254950_-	hypothetical protein	A0A1B3AZZ6	Gordonia_phage	1.2e-16	60.8
WP_062919189.1\|256370_258086_+	TROVE domain-containing protein	A0A076GDS2	Mycobacterium_phage	3.2e-206	63.9
WP_052536723.1\|258092_258323_+	hypothetical protein	A0A076G7T2	Mycobacterium_phage	1.1e-16	70.3
WP_062919190.1\|258494_258824_+	hypothetical protein	NA	NA	NA	NA
WP_062919191.1\|258830_259217_+	hypothetical protein	K4JS85	Caulobacter_phage	2.9e-06	30.7
WP_052536720.1\|259213_259453_+	hypothetical protein	NA	NA	NA	NA
WP_062919192.1\|259449_259914_+	hypothetical protein	NA	NA	NA	NA
WP_062919193.1\|259898_260204_+	hypothetical protein	A0A068F8P5	Mycobacterium_phage	4.2e-08	55.6
WP_078345221.1\|260200_260878_+	hypothetical protein	A0A142F2N6	Mycobacterium_phage	3.6e-12	58.5

DBSCAN-SWA_2

268136 : 307970

Mycobacterium_phage(92.0%)

head,integrase,holin,capsid,tail,protease,portal

attL 302067:302081|attR 304716:304730

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079767739.1\|268136_269645_+	hypothetical protein	A0A0F6WE93	Mycobacterium_phage	2.2e-73	38.5
WP_062869421.1\|269645_270095_+	hypothetical protein	NA	NA	NA	NA
WP_109545027.1\|270057_271668_+	hypothetical protein	A0A142F2D8	Mycobacterium_phage	1.0e-209	67.3
WP_062919207.1\|271834_273142_+\|portal	phage portal protein	A0A142F2E0	Mycobacterium_phage	2.9e-130	56.6
WP_079767397.1\|273138_274023_+\|head,protease	HK97 family phage prohead protease	A0A142F2E1	Mycobacterium_phage	1.4e-80	57.3
WP_062919208.1\|274216_275596_+\|capsid	phage major capsid protein	A0A142F2E2	Mycobacterium_phage	3.1e-167	67.3
WP_052536701.1\|275686_276028_+	hypothetical protein	NA	NA	NA	NA
WP_052536700.1\|276002_276557_+	hypothetical protein	A0A142F2E4	Mycobacterium_phage	6.8e-41	47.5
WP_062919209.1\|276553_276931_+	hypothetical protein	NA	NA	NA	NA
WP_052536698.1\|276930_277179_+	hypothetical protein	A0A142F2E6	Mycobacterium_phage	4.6e-21	61.7
WP_052536697.1\|277178_277616_+	hypothetical protein	NA	NA	NA	NA
WP_052536696.1\|277692_278274_+	hypothetical protein	A0A142F2E8	Mycobacterium_phage	2.3e-87	81.3
WP_052536695.1\|278270_278669_+	hypothetical protein	A0A142F2E9	Mycobacterium_phage	5.1e-22	55.7
WP_052536694.1\|278788_279103_+	hypothetical protein	A0A142F2F0	Mycobacterium_phage	3.5e-18	52.1
WP_153995377.1\|279099_283809_+\|tail	phage tail tape measure protein	A0A142F2F1	Mycobacterium_phage	5.8e-290	44.6
WP_062869433.1\|283805_284819_+	hypothetical protein	A0A142F2F2	Mycobacterium_phage	2.0e-139	69.5
WP_079767740.1\|284819_286655_+	hypothetical protein	A0A142F2F3	Mycobacterium_phage	5.3e-300	80.5
WP_062919211.1\|286654_287266_+	hypothetical protein	A0A142F2F4	Mycobacterium_phage	1.7e-72	75.8
WP_062869437.1\|287266_288670_+	hypothetical protein	A0A142F2F5	Mycobacterium_phage	8.8e-162	60.1
WP_062919213.1\|291370_292504_+	hypothetical protein	G1DA55	Mycobacterium_virus	7.5e-10	53.8
WP_153995378.1\|292512_292863_+	hypothetical protein	A0A249XMQ7	Mycobacterium_phage	9.6e-09	56.1
WP_153995379.1\|292859_293210_+	hypothetical protein	NA	NA	NA	NA
WP_109530880.1\|294057_294849_+	N-acetylmuramoyl-L-alanine amidase	A0A0A0RKX1	Mycobacterium_phage	3.6e-104	72.8
WP_062919217.1\|294845_296012_+	hypothetical protein	A0A023ZXI5	Mycobacterium_phage	1.0e-147	66.0
WP_062869451.1\|296065_296443_+	hypothetical protein	A0A0M3UKI2	Mycobacterium_phage	3.9e-24	50.0
WP_052536682.1\|296451_296850_+	DUF2746 domain-containing protein	A0A249XUL1	Mycobacterium_phage	6.7e-06	36.9
WP_131830718.1\|296950_297172_+	hypothetical protein	NA	NA	NA	NA
WP_062919218.1\|297179_297833_-	DUF1851 domain-containing protein	NA	NA	NA	NA
WP_062920218.1\|297829_300001_-	hypothetical protein	NA	NA	NA	NA
WP_062869454.1\|300033_300354_-	hypothetical protein	NA	NA	NA	NA
WP_153995380.1\|300513_300966_-	hypothetical protein	NA	NA	NA	NA
WP_062869458.1\|301088_301397_+	hypothetical protein	NA	NA	NA	NA
WP_062919221.1\|301532_302717_+	hypothetical protein	A0A142F2H7	Mycobacterium_phage	1.0e-118	55.4
302067:302081	attL	NA	NA	NA	NA
WP_062919222.1\|302767_303064_-	hypothetical protein	NA	NA	NA	NA
WP_079612496.1\|303089_304094_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1SGM4	Mycobacterium_phage	1.6e-96	61.5
WP_005065283.1\|304379_304814_+	hypothetical protein	NA	NA	NA	NA
304716:304730	attR	NA	NA	NA	NA
WP_005065285.1\|304803_305355_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005063057.1\|305351_305945_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_005063058.1\|306056_306281_+	hypothetical protein	A0A076YS62	Mycobacterium_phage	8.6e-11	46.2
WP_005063059.1\|306380_307970_+\|holin	glucose-methanol-choline oxidoreductase	A0A1V0S9M4	Catovirus	4.2e-51	29.7

DBSCAN-SWA_3

507277 : 550739

Mycobacterium_phage(74.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062919257.1\|507277_508237_+	hypothetical protein	A0A023ZXB3	Mycobacterium_phage	2.4e-81	49.0
WP_062919258.1\|508233_509289_+	hypothetical protein	A0A2D1GGG2	Gordonia_phage	1.3e-56	45.2
WP_062919259.1\|509288_509528_+	hypothetical protein	NA	NA	NA	NA
WP_062919260.1\|509535_509934_+	hypothetical protein	NA	NA	NA	NA
WP_062919261.1\|509986_510484_+	hypothetical protein	NA	NA	NA	NA
WP_062919262.1\|510471_510888_+	hypothetical protein	NA	NA	NA	NA
WP_062919263.1\|510884_511145_+	hypothetical protein	NA	NA	NA	NA
WP_062919264.1\|511141_511723_+	hypothetical protein	A0A1L6BYL0	Mycobacterium_phage	1.6e-29	53.7
WP_062919265.1\|511719_512115_+	hypothetical protein	A0A059VL25	Mycobacterium_phage	1.1e-24	50.4
WP_062919266.1\|512111_513683_+	DNA methyltransferase	A0A142KB20	Gordonia_phage	9.9e-178	58.7
WP_153995383.1\|513900_514233_+	hypothetical protein	NA	NA	NA	NA
WP_062919268.1\|514225_515134_+	phage Gp37/Gp68 family protein	A0A2P1A0W3	Gordonia_phage	5.2e-115	66.4
WP_062919269.1\|515299_515557_+	NrdH-redoxin	A0A2H4PFR8	Mycobacterium_phage	2.2e-18	55.1
WP_062919270.1\|515556_516501_+	hypothetical protein	E0YQ62	Mycobacterium_phage	4.0e-65	56.5
WP_062919272.1\|517273_517639_+	hypothetical protein	NA	NA	NA	NA
WP_062919273.1\|517635_517878_+	hypothetical protein	NA	NA	NA	NA
WP_062919274.1\|517874_518492_+	hypothetical protein	A0A142KBT1	Gordonia_phage	1.3e-29	38.6
WP_016892133.1\|518492_518831_+	WhiB family transcriptional regulator	A0A2H4JGM8	uncultured_Caudovirales_phage	1.9e-06	39.2
WP_062919275.1\|518874_519555_+	hypothetical protein	A0A1B3AYN8	Gordonia_phage	4.1e-64	59.6
WP_062919276.1\|519569_519764_+	hypothetical protein	NA	NA	NA	NA
WP_062919277.1\|519760_520165_+	hypothetical protein	NA	NA	NA	NA
WP_153995384.1\|521849_522296_+	hypothetical protein	NA	NA	NA	NA
WP_062920222.1\|522292_522559_+	hypothetical protein	NA	NA	NA	NA
WP_062919280.1\|522551_522830_+	hypothetical protein	S5W0L6	Mycobacterium_phage	1.9e-12	55.9
WP_052534401.1\|522960_523242_+	hypothetical protein	NA	NA	NA	NA
WP_062920223.1\|523491_523935_+	hypothetical protein	A0A023ZWK1	Mycobacterium_phage	7.4e-14	40.4
WP_062919281.1\|523891_525565_+	hypothetical protein	A0A2K9VEU8	Mycobacterium_phage	3.7e-122	46.0
WP_062919282.1\|525616_527020_+	hypothetical protein	A0A023ZWK5	Mycobacterium_phage	2.3e-146	60.0
WP_062919283.1\|527019_528273_+	peptidase	A0A1B3AZ47	Gordonia_phage	2.4e-70	45.7
WP_062919284.1\|528274_528727_+	hypothetical protein	A0A142KBL3	Gordonia_phage	2.2e-45	70.3
WP_016892118.1\|528759_529704_+	hypothetical protein	A0A142KC12	Gordonia_phage	1.5e-104	59.5
WP_062919285.1\|529700_530123_+	hypothetical protein	NA	NA	NA	NA
WP_062919286.1\|530129_530525_+	hypothetical protein	A0A023ZWL1	Mycobacterium_phage	1.9e-16	45.5
WP_062919287.1\|530518_531205_+	hypothetical protein	A0A2K9VET7	Mycobacterium_phage	6.3e-36	42.5
WP_062919288.1\|531204_531447_+	hypothetical protein	A0A2K9VEX1	Mycobacterium_phage	1.4e-14	53.2
WP_062919289.1\|531443_531866_+	hypothetical protein	W8EG37	Mycobacterium_phage	3.1e-17	45.2
WP_062919290.1\|531886_532429_+	hypothetical protein	A0A023ZYD0	Mycobacterium_phage	4.3e-64	66.1
WP_062919291.1\|532444_532732_+	hypothetical protein	NA	NA	NA	NA
WP_062919292.1\|532703_533447_+	hypothetical protein	A0A023ZX24	Mycobacterium_phage	1.8e-33	37.6
WP_062919293.1\|533452_533752_+	hypothetical protein	NA	NA	NA	NA
WP_062919294.1\|533946_537672_+	hypothetical protein	S5Y5B9	Mycobacterium_phage	3.4e-51	48.6
WP_025982991.1\|537671_538778_+	hypothetical protein	A0A023ZWM1	Mycobacterium_phage	3.1e-146	63.5
WP_062919295.1\|538774_540493_+	hypothetical protein	A0A023ZX29	Mycobacterium_phage	4.4e-264	73.5
WP_062919296.1\|540492_541047_+	hypothetical protein	A0A023ZXQ6	Mycobacterium_phage	2.3e-20	41.0
WP_062919297.1\|541043_542150_+	hypothetical protein	A0A023ZX82	Mycobacterium_phage	8.4e-115	56.2
WP_062919298.1\|542149_544276_+	hypothetical protein	A0A2P1JZR8	Mycobacterium_phage	8.7e-44	40.9
WP_062920224.1\|544377_546015_+	hypothetical protein	A0A2P1JQM8	Mycobacterium_phage	4.6e-37	35.7
WP_062919299.1\|546042_546450_+	hypothetical protein	X2KN63	Mycobacterium_phage	8.8e-38	61.5
WP_062920225.1\|546654_546918_+	hypothetical protein	NA	NA	NA	NA
WP_062919300.1\|546914_548414_+	N-acetylmuramoyl-L-alanine amidase	A0A2D1GPR8	Mycobacterium_phage	1.8e-80	40.2
WP_062919301.1\|548410_549577_+	hypothetical protein	A0A023ZXI5	Mycobacterium_phage	1.0e-150	67.6
WP_016895933.1\|549591_549831_+	membrane protein	NA	NA	NA	NA
WP_016892097.1\|549830_550184_+	hypothetical protein	NA	NA	NA	NA
WP_062919302.1\|550190_550739_+	hypothetical protein	A0A2K9VF19	Mycobacterium_phage	2.8e-31	44.8

DBSCAN-SWA_4

867511 : 896998

Mycobacterium_phage(86.67%)

protease,integrase

attL 867456:867470|attR 888244:888258

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
867456:867470	attL	NA	NA	NA	NA
WP_062919341.1\|867511_868777_+\|integrase	tyrosine-type recombinase/integrase	A0A222ZRP3	Mycobacterium_phage	3.5e-101	47.3
WP_062919342.1\|868780_869551_-	hypothetical protein	A0A068F4L5	Mycobacterium_phage	6.1e-56	49.2
WP_005089876.1\|869656_870016_-	hypothetical protein	NA	NA	NA	NA
WP_005089874.1\|870153_870426_+	hypothetical protein	A0A222ZRD7	Mycobacterium_phage	3.7e-08	36.7
WP_005089873.1\|870422_870638_+	helix-turn-helix domain-containing protein	G8IR38	Mycobacterium_virus	1.2e-09	51.7
WP_062919343.1\|870639_870951_+	hypothetical protein	NA	NA	NA	NA
WP_131721800.1\|871585_871894_+	hypothetical protein	A0A222ZMV4	Mycobacterium_phage	5.3e-19	47.9
WP_062919344.1\|872204_872978_+	hypothetical protein	A0A222ZNH4	Mycobacterium_phage	1.0e-79	53.4
WP_074292784.1\|872974_873178_+	hypothetical protein	A0A1B1P7Q3	Bacillus_phage	1.3e-05	35.9
WP_062919346.1\|873440_874343_+\|protease	membrane protease subunit, stomatin/prohibitin	A0A0M5M0P3	Mycobacterium_phage	5.4e-88	59.1
WP_052535282.1\|874604_874901_+	hypothetical protein	NA	NA	NA	NA
WP_062919347.1\|874875_876309_+	DUF2828 family protein	A0A1D8EPU2	Mycobacterium_phage	1.8e-162	61.9
WP_153995386.1\|877019_877205_+	hypothetical protein	NA	NA	NA	NA
WP_062919348.1\|877229_878069_+	hypothetical protein	A0A2H4J3W2	uncultured_Caudovirales_phage	1.8e-77	53.6
WP_079767751.1\|878516_879278_+	hypothetical protein	H6U5J4	Mycobacterium_phage	1.3e-58	52.5
WP_062919349.1\|879440_879788_+	hypothetical protein	A0A2D2W3B6	Mycobacterium_phage	8.9e-31	60.2
WP_062919350.1\|879818_880055_+	hypothetical protein	NA	NA	NA	NA
WP_065211451.1\|880733_881396_+	hypothetical protein	A0A0K2FNB6	Mycobacterium_phage	2.1e-60	50.9
WP_065211452.1\|881392_882664_+	AAA family ATPase	A0A0M3UKG3	Mycobacterium_phage	1.2e-117	51.9
WP_079767752.1\|883366_884128_+	hypothetical protein	H6U5K5	Mycobacterium_phage	1.3e-61	50.8
WP_062919352.1\|884124_885615_+	nicotinate phosphoribosyltransferase	A0A0M4R260	Mycobacterium_phage	3.0e-216	75.0
WP_062919353.1\|885964_886894_+	AAA family ATPase	A0A0M4QU41	Mycobacterium_phage	4.7e-127	72.8
WP_079767753.1\|887190_887382_+	hypothetical protein	A0A0M4RQK6	Mycobacterium_phage	3.1e-09	68.2
WP_062919355.1\|887374_887725_+	hypothetical protein	NA	NA	NA	NA
WP_079767754.1\|887744_888116_+	RusA family crossover junction endodeoxyribonuclease	A0A286MQI7	Mycobacterium_phage	4.9e-35	57.5
WP_079767878.1\|888197_888623_+	WhiB family transcriptional regulator	A0A2P1CGA4	Mycobacterium_phage	2.9e-07	44.7
888244:888258	attR	NA	NA	NA	NA
WP_062919356.1\|889175_890021_+	hypothetical protein	H6U5J3	Mycobacterium_phage	7.7e-52	52.7
WP_062919357.1\|890013_890415_+	single-stranded DNA-binding protein	A0A222ZMU2	Mycobacterium_phage	3.5e-31	59.2
WP_079767755.1\|890438_890843_+	DUF2493 domain-containing protein	A0A291I9Y2	Mycobacterium_phage	3.4e-42	63.4
WP_062919358.1\|891179_892460_+	hypothetical protein	A0A1D8EPX0	Mycobacterium_phage	3.7e-159	64.7
WP_005089818.1\|892507_892792_+	hypothetical protein	A0A222ZMY0	Mycobacterium_phage	4.6e-17	44.8
WP_032702005.1\|892843_893248_+	hypothetical protein	A0A222ZP47	Mycobacterium_phage	4.3e-37	58.8
WP_065211453.1\|893806_894124_+	DUF3310 domain-containing protein	A0A222ZST3	Mycobacterium_phage	1.2e-18	67.7
WP_062919359.1\|894113_894899_+	hypothetical protein	B5A774	Mycobacterium_virus	2.0e-107	69.7
WP_062919360.1\|895408_895648_+	hypothetical protein	NA	NA	NA	NA
WP_131833163.1\|895845_896031_+	hypothetical protein	NA	NA	NA	NA
WP_153995387.1\|896109_896382_+	hypothetical protein	A0A0M4RBN9	Mycobacterium_phage	1.4e-10	73.6
WP_062919361.1\|896752_896998_+	hypothetical protein	A0A286MQK7	Mycobacterium_phage	5.7e-16	60.3

DBSCAN-SWA_5

905363 : 929481

Mycobacterium_phage(90.48%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_074292738.1\|905363_905579_-	hypothetical protein	A0A222ZSP7	Mycobacterium_phage	4.5e-09	45.3
WP_062919368.1\|905624_906191_-	hypothetical protein	A0A291IA04	Mycobacterium_phage	5.3e-49	59.8
WP_153995389.1\|906194_906428_-	hypothetical protein	A0A2P1JUA2	Erwinia_phage	7.1e-08	44.8
WP_062919370.1\|906767_907025_-	hypothetical protein	NA	NA	NA	NA
WP_131804345.1\|907267_908104_-	hypothetical protein	A0A222ZN27	Mycobacterium_phage	2.8e-38	34.3
WP_062919372.1\|908178_909369_-	AAA domain-containing protein	A0A222ZT54	Mycobacterium_phage	1.3e-44	38.4
WP_153995390.1\|909734_909908_-	hypothetical protein	NA	NA	NA	NA
WP_153995391.1\|910109_910361_-	hypothetical protein	NA	NA	NA	NA
WP_079767880.1\|911092_911452_+	hypothetical protein	A0A286MQB1	Mycobacterium_phage	3.1e-26	59.1
WP_153995392.1\|911635_912385_+	hypothetical protein	A0A222ZMR5	Mycobacterium_phage	2.8e-45	40.9
WP_050545121.1\|912381_913233_+	hypothetical protein	A0A222ZMR5	Mycobacterium_phage	3.7e-86	57.8
WP_062919377.1\|913244_914690_+\|portal	phage portal protein	A0A0M3UK79	Mycobacterium_phage	3.7e-139	55.2
WP_062919378.1\|914710_915805_+	hypothetical protein	A0A0M4R9T5	Mycobacterium_phage	1.5e-79	45.4
WP_005089753.1\|915861_916488_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_062919379.1\|916525_917695_+	hypothetical protein	A0A0M4S3M0	Mycobacterium_phage	2.9e-97	51.8
WP_062920233.1\|917744_918182_+	hypothetical protein	A0A0K2FNR3	Mycobacterium_phage	9.5e-30	51.7
WP_032701992.1\|918147_918501_+	hypothetical protein	A0A0K2FN66	Mycobacterium_phage	5.9e-22	50.5
WP_032701991.1\|918513_918909_+	hypothetical protein	NA	NA	NA	NA
WP_005089747.1\|918921_919398_+	hypothetical protein	A0A286MQC1	Mycobacterium_phage	7.9e-54	59.2
WP_062919380.1\|919440_920337_+	Ig-like domain-containing protein	A0A0U4JMB7	Mycobacterium_phage	9.4e-133	78.5
WP_062919381.1\|920425_920746_+	hypothetical protein	A0A173G9Z1	Mycobacterium_phage	5.5e-27	63.2
WP_131833159.1\|920967_921255_+	hypothetical protein	A0A1B1SEV9	Mycobacterium_phage	2.5e-23	59.6
WP_079767881.1\|921562_926290_+	hypothetical protein	F6M811	Mycobacterium_virus	6.8e-291	49.9
WP_062919384.1\|926368_927250_+	hypothetical protein	G1BRU3	Mycobacterium_phage	5.8e-151	83.5
WP_079583915.1\|927222_929010_+	hypothetical protein	H6U5F0	Mycobacterium_phage	4.4e-283	78.3
WP_062919385.1\|929031_929481_+	hypothetical protein	A0A0K2FNS6	Mycobacterium_phage	1.4e-39	51.7

DBSCAN-SWA_6

2933822 : 2942381

Streptococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062919704.1\|2933822_2934494_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	2.9e-17	31.6
WP_005057567.1\|2934607_2935531_+	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	1.1e-08	31.6
WP_005068900.1\|2935532_2936402_+	class A beta-lactamase	A0A1B0VBP7	Salmonella_phage	1.5e-55	46.0
WP_005068903.1\|2936503_2938870_-	RelA/SpoT family protein	A0A291L9W9	Bordetella_phage	1.8e-13	38.4
WP_005068905.1\|2938900_2939434_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.1e-14	36.4
WP_016892305.1\|2939430_2941107_-	hypothetical protein	NA	NA	NA	NA
WP_016892306.1\|2941106_2942381_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.5e-22	28.6

DBSCAN-SWA_7

4307272 : 4353038

Mycobacterium_phage(73.33%)

terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005061616.1\|4307272_4308103_-	NAD(P)-dependent oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	5.7e-07	29.1
WP_062920037.1\|4308230_4308521_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005070857.1\|4308641_4308833_+	hypothetical protein	NA	NA	NA	NA
WP_049233916.1\|4308829_4309594_+	antirepressor	A0A142K8T5	Gordonia_phage	2.5e-49	48.1
WP_017555346.1\|4309697_4310084_+	hypothetical protein	NA	NA	NA	NA
WP_017555347.1\|4310080_4310401_+	hypothetical protein	NA	NA	NA	NA
WP_017555348.1\|4310400_4310943_+	hypothetical protein	A0A218M960	Mycobacterium_phage	1.0e-41	58.1
WP_017555349.1\|4310939_4311290_+	hypothetical protein	J7KDJ6	Mycobacterium_virus	7.4e-25	53.2
WP_062920038.1\|4311286_4311547_+	hypothetical protein	NA	NA	NA	NA
WP_017555351.1\|4311543_4312428_+	hypothetical protein	A0A1B3AYT6	Gordonia_phage	2.0e-103	63.3
WP_079270977.1\|4312400_4313450_+	hypothetical protein	A0A160DCX2	Gordonia_phage	2.0e-49	44.8
WP_017555353.1\|4313452_4313794_+	hypothetical protein	G8I4S2	Mycobacterium_phage	4.5e-35	68.1
WP_005061650.1\|4313821_4314658_+	DUF2303 family protein	G8I4S3	Mycobacterium_phage	1.3e-104	67.3
WP_025988934.1\|4314669_4315533_+	SPFH domain-containing protein	A0A0M4RAA7	Mycobacterium_phage	1.8e-72	52.9
WP_017555355.1\|4315543_4316068_+	hypothetical protein	A0A0F6WF12	Mycobacterium_phage	7.6e-42	53.6
WP_017555356.1\|4316064_4316481_+	hypothetical protein	NA	NA	NA	NA
WP_017555357.1\|4316477_4317002_+	hypothetical protein	A0A1J0MDV9	Mycobacterium_phage	1.7e-09	30.3
WP_153995443.1\|4317094_4318144_+	site-specific DNA-methyltransferase	A0A2H4GSZ1	Mycobacterium_phage	2.3e-98	55.2
WP_062920040.1\|4318333_4318657_+	hypothetical protein	A0A159B6R8	Tsukamurella_phage	2.0e-29	57.8
WP_062920341.1\|4318656_4318965_+	hypothetical protein	A0A076G9B0	Mycobacterium_phage	3.3e-21	48.3
WP_062920041.1\|4318961_4319282_+	hypothetical protein	A0A2H4JB07	uncultured_Caudovirales_phage	2.4e-06	43.4
WP_062920042.1\|4319406_4319856_+	hypothetical protein	Q6JIG5	Burkholderia_virus	9.4e-41	61.2
WP_062920342.1\|4319855_4320224_+	hypothetical protein	A0A1D8EX67	Mycobacterium_phage	9.7e-52	80.2
WP_062920043.1\|4320216_4320600_+	hypothetical protein	NA	NA	NA	NA
WP_109556946.1\|4320592_4321018_+	DUF4326 domain-containing protein	A0A142KCP7	Gordonia_phage	7.1e-30	50.0
WP_062920045.1\|4321017_4321761_+	hypothetical protein	A0A076YNI8	Mycobacterium_phage	4.4e-35	49.6
WP_062920046.1\|4321830_4322199_+	hypothetical protein	NA	NA	NA	NA
WP_062920047.1\|4322195_4322483_+	hypothetical protein	B5U3D3	Mycobacterium_virus	3.2e-34	74.4
WP_062920343.1\|4322900_4323911_+	hypothetical protein	NA	NA	NA	NA
WP_062920048.1\|4324534_4324825_+	hypothetical protein	NA	NA	NA	NA
WP_062873664.1\|4325317_4325512_+	hypothetical protein	A0A1I9SC44	Mycobacterium_phage	8.5e-15	59.4
WP_062873665.1\|4325511_4325748_+	hypothetical protein	A0A2K9VEW2	Mycobacterium_phage	1.1e-21	59.7
WP_062873666.1\|4325775_4326273_+	hypothetical protein	NA	NA	NA	NA
WP_079767855.1\|4326468_4326732_-	hypothetical protein	NA	NA	NA	NA
WP_074243865.1\|4327017_4327272_+	hypothetical protein	G3M5G1	Mycobacterium_phage	6.1e-21	57.6
WP_062920050.1\|4327268_4327622_+	hypothetical protein	A0A088F7V7	Mycobacterium_phage	1.4e-15	52.0
WP_062920344.1\|4327728_4327992_+	hypothetical protein	A0A1D8EX45	Mycobacterium_phage	3.7e-29	71.3
WP_062920051.1\|4327988_4328441_+	AAA family ATPase	A0A1D8EX78	Mycobacterium_phage	1.7e-53	66.7
WP_057138161.1\|4328601_4329003_+	hypothetical protein	A0A023ZWK1	Mycobacterium_phage	1.8e-06	33.0
WP_005070911.1\|4329151_4330564_+\|terminase	terminase	R4TCB6	Mycobacterium_phage	3.7e-152	57.2
WP_062920052.1\|4330578_4332027_+	hypothetical protein	A0A249XTF7	Mycobacterium_phage	2.9e-168	65.4
WP_062920053.1\|4332020_4333274_+	peptidase S14	A0A1B3AZ47	Gordonia_phage	4.1e-86	51.3
WP_005070916.1\|4333277_4333655_+	hypothetical protein	W8EH90	Mycobacterium_phage	6.2e-46	82.4
WP_005070919.1\|4333671_4334583_+	hypothetical protein	A0A2K9VEV5	Mycobacterium_phage	1.2e-138	81.1
WP_062920054.1\|4334582_4335032_+	hypothetical protein	NA	NA	NA	NA
WP_005070923.1\|4335036_4335399_+	hypothetical protein	A0A218M9J6	Mycobacterium_phage	3.2e-31	58.3
WP_062920055.1\|4335398_4335806_+	hypothetical protein	NA	NA	NA	NA
WP_050886884.1\|4335805_4336165_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_062920056.1\|4336164_4336575_+	hypothetical protein	NA	NA	NA	NA
WP_062920057.1\|4336665_4337745_+	hypothetical protein	G1JTF7	Mycobacterium_virus	7.0e-58	44.1
WP_062920058.1\|4337840_4338287_+	hypothetical protein	A0A0A7RVK9	Mycobacterium_phage	1.3e-26	43.0
WP_005070934.1\|4338348_4338711_+	hypothetical protein	A0A2P1JR40	Mycobacterium_phage	1.7e-29	62.6
WP_062920059.1\|4338725_4342352_+	hypothetical protein	A0A0B5H802	Mycobacterium_phage	2.8e-207	43.7
WP_049234017.1\|4342348_4344079_+	hypothetical protein	A0A1I9SC71	Mycobacterium_phage	1.1e-198	58.8
WP_079767856.1\|4344119_4345826_+	hypothetical protein	A0A097EYM8	Mycobacterium_phage	4.5e-269	77.8
WP_062873677.1\|4345841_4346681_+	hypothetical protein	A0A142K812	Mycobacterium_phage	9.2e-82	54.3
WP_062920061.1\|4346677_4349125_+	hypothetical protein	A0A2P1JZR8	Mycobacterium_phage	7.4e-47	30.0
WP_062920062.1\|4349208_4350180_+	hypothetical protein	A0A059VL91	Mycobacterium_phage	6.4e-26	55.9
WP_062920063.1\|4350202_4350658_+	hypothetical protein	NA	NA	NA	NA
WP_062920064.1\|4350677_4351076_+	hypothetical protein	A0A221J765	Mycobacterium_phage	2.8e-52	79.4
WP_062920065.1\|4351218_4351866_+	M15 family metallopeptidase	A0A0K1LIU2	Mycobacterium_phage	2.4e-98	77.2
WP_062920066.1\|4351862_4353038_+	hypothetical protein	A0A1X9SFG9	Mycobacterium_phage	1.8e-123	70.9

DBSCAN-SWA_8

4527882 : 4537378

Burkholderia_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062920103.1\|4527882_4529007_-	acyltransferase	A9YX16	Burkholderia_phage	7.1e-21	28.7
WP_005071257.1\|4529003_4530272_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	3.3e-06	40.3
WP_012296730.1\|4530321_4531128_-	macrocin O-methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	4.9e-56	52.6
WP_005138043.1\|4531338_4532031_-	class I SAM-dependent methyltransferase	Q98VI8	Paramecium_bursaria_Chlorella_virus	3.7e-12	30.2
WP_062920104.1\|4532263_4533394_-	acyltransferase	A9YX16	Burkholderia_phage	5.3e-16	26.3
WP_062920105.1\|4533561_4534623_-	NAD-dependent epimerase/dehydratase family protein	A0A0E3IB24	Synechococcus_phage	2.6e-17	25.8
WP_062920348.1\|4534786_4536046_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	1.6e-05	39.2
WP_079636292.1\|4536188_4536488_-	hypothetical protein	NA	NA	NA	NA
WP_005062166.1\|4536511_4537378_+	glucose-1-phosphate thymidylyltransferase RfbA	H9NC64	Sphingomonas_phage	2.8e-89	57.5

DBSCAN-SWA_9

5223491 : 5231863

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005103079.1\|5223491_5224961_+	serine hydrolase	A0A1J0GRK9	Mycobacterium_phage	9.4e-13	28.5
WP_005082750.1\|5225088_5225901_+	DUF1906 domain-containing protein	A0A2D1GEF2	Gordonia_phage	3.1e-50	49.1
WP_016893138.1\|5225949_5227146_-	LysM peptidoglycan-binding domain-containing protein	A0A1W6JL93	Lactococcus_phage	2.6e-05	47.3
WP_005100934.1\|5227575_5228424_+	N-acetylmuramoyl-L-alanine amidase	A0A2D1GEV9	Mycobacterium_phage	3.6e-65	55.6
WP_005101057.1\|5228590_5228893_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_005100873.1\|5229184_5229634_+	hypothetical protein	NA	NA	NA	NA
WP_005072025.1\|5229654_5231106_+	HAMP domain-containing histidine kinase	Q8QKV4	Ectocarpus_siliculosus_virus	2.9e-06	33.6
WP_005064635.1\|5231185_5231863_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.4e-26	31.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP014961

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection