CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP012288	Pediococcus damnosus strain TMW 2.1535 chromosome, complete genome	4 crisprs	DinG,RT,WYL,cas9,cas1,cas2,csn2,cas3,DEDDh,csa3	1	9	17
NZ_CP012291	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-3, complete sequence	1 crisprs	NA	0	2	1
NZ_CP012293	Pediococcus damnosus strain TMW 2.1535 plasmid unnamed	0 crisprs	NA	0	0	0
NZ_CP012289	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-1, complete sequence	0 crisprs	NA	0	0	1
NZ_CP012290	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-2, complete sequence	0 crisprs	NA	0	0	5
NZ_CP012292	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-4, complete sequence	1 crisprs	csa3	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012288_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012288_1

623926-624065

Orphan

Consensus_repeat	Method
GATTTTGCGTATGCAACATAGTCATTTAAAAATCGAGGAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012288_1

>merge|NZ_CP012288|1|623926-624065|CRISPRCasFinder
GATTTTGCGTATGCAACATAGTCATTTAAAAATCGAGGAGGGCCAGTCCGACTTGGCATTGGAATGCCATAGCAAGGATGGACACCGTACCGAGAATAGGATTTTGCGTATGCAAAATAGTCATTTAAAAATCGAGGAGG

>NZ_CP012288|1|1|623926-624065|CRISPRCasFinder
GATTTTGCGTATGCAACATAGTCATTTAAAAATCGAGGAGG	GCCAGTCCGACTTGGCATTGGAATGCCATAGCAAGGATGGACACCGTACCGAGAATAG
GATTTTGCGTATGCAAAATAGTCATTTAAAAATCGAGGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012288.1\|WP_046871516.1\|615312_616131_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP012288.1\|WP_046871528.1\|628955_629822_-\|viroplasmin-family-protein	unknown	unknown	gnl\|CDD\|260010
NZ_CP012288.1\|WP_046871529.1\|629963_630146_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_046872291.1\|630432_631800_-\|ISLre2-family-transposase	unknown	unknown	gnl\|CDD\|284250
NZ_CP012288.1\|WP_046871530.1\|632101_632353_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_046871520.1\|622377_622830_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP012288.1\|WP_062904288.1\|617007_618213_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP012288.1\|WP_046871515.1\|612464_613547_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_062916563.1\|626171_627365_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP012288.1\|WP_046871527.1\|628418_628946_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP012288.1\|WP_046871523.1\|624480_624981_-\|O-acetyl-ADP-ribose-deacetylase	unknown	unknown	gnl\|CDD\|394878
NZ_CP012288.1\|WP_046871524.1\|624993_626160_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_056986319.1\|618759_620655_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP012288.1\|WP_046871519.1\|620641_622378_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP012288.1\|WP_062904581.1\|613818_615066_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP012288.1\|WP_046871522.1\|624072_624261_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_046871521.1\|623012_623693_-\|noncanonical-pyrimidine-nucleotidase,-YjjG-family	unknown	unknown	gnl\|CDD\|162788
NZ_CP012288.1\|WP_046871517.1\|616147_616471_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_046871526.1\|627510_627891_-\|iron-sulfur-cluster-biosynthesis-family-protein	unknown	unknown	gnl\|CDD\|366687
NZ_CP012288.1\|WP_046871514.1\|611453_612011_-\|DUF5067-domain-containing-protein	unknown	unknown	gnl\|CDD\|374759

Protein	Function_ID	Function_description	E-value
NZ_CP012288.1\|WP_046871516.1\|615312_616131_-\|HAD-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.38745e-46
NZ_CP012288.1\|WP_046871528.1\|628955_629822_-\|viroplasmin-family-protein	gnl\|CDD\|260010	cd09278, RNase_HI_prokaryote_like, RNase HI family found mainly in prokaryotes. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD), residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Prokaryotic RNase H varies greatly in domain structures and substrate specificities. Prokaryotes and some single-cell eukaryotes do not require RNase H for viability.	1.14956e-55
NZ_CP012288.1\|WP_046872291.1\|630432_631800_-\|ISLre2-family-transposase	gnl\|CDD\|284250	pfam06782, UPF0236, Uncharacterized protein family (UPF0236).	1.04753e-29
NZ_CP012288.1\|WP_046871520.1\|622377_622830_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.60261e-12
NZ_CP012288.1\|WP_062904288.1\|617007_618213_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	8.98508e-26
NZ_CP012288.1\|WP_062916563.1\|626171_627365_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.30489e-54
NZ_CP012288.1\|WP_046871527.1\|628418_628946_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.40699e-18
NZ_CP012288.1\|WP_046871523.1\|624480_624981_-\|O-acetyl-ADP-ribose-deacetylase	gnl\|CDD\|394878	cd02908, Macro_OAADPr_deacetylase, macrodomain, O-acetyl-ADP-ribose (OAADPr) family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. This family includes eukaryotic macrodomain proteins such as human MacroD1 and MacroD2, and bacterial proteins such as Escherichia coli YmdB; these have been shown to be O-acetyl-ADP-ribose (OAADPr) deacetylases that efficiently catalyze the hydrolysis of OAADPr to produce ADP-ribose and free acetate. OAADPr is a sirtuin reaction product generated from the NAD+-dependent protein deacetylation reactions and has been implicated as a signaling molecule. By acting on mono-ADP-ribosylated substrates, OAADPr deacteylases may reverse cellular ADP-ribosylation.	9.67097e-95
NZ_CP012288.1\|WP_056986319.1\|618759_620655_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.45124e-177
NZ_CP012288.1\|WP_046871519.1\|620641_622378_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.45696e-162
NZ_CP012288.1\|WP_062904581.1\|613818_615066_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.21343e-46
NZ_CP012288.1\|WP_046871521.1\|623012_623693_-\|noncanonical-pyrimidine-nucleotidase,-YjjG-family	gnl\|CDD\|162788	TIGR02254, hydrolase_haloacid_dehalogenase-like_family, noncanonical pyrimidine nucleotidase, YjjG family. This HAD superfamily includes including YjjG from E. coli and YfnB from B. subtilis. YjjG has been shown to act as a house-cleaning enzyme, cleaving nucleotides with non-canonical nucleotide bases. This family is a member of the haloacid dehalogenase (HAD) superfamily of hydrolases which are characterized by three conserved sequence motifs. By virtue of an alpha helical domain in-between the first and second conserved motif, this family is a member of subfamily IA (TIGR01549).	1.40992e-72
NZ_CP012288.1\|WP_046871526.1\|627510_627891_-\|iron-sulfur-cluster-biosynthesis-family-protein	gnl\|CDD\|366687	pfam01521, Fe-S_biosyn, Iron-sulphur cluster biosynthesis. This family is involved in iron-sulphur cluster biosynthesis. Its members include proteins that are involved in nitrogen fixation such as the HesB and HesB-like proteins.	8.07463e-21
NZ_CP012288.1\|WP_046871514.1\|611453_612011_-\|DUF5067-domain-containing-protein	gnl\|CDD\|374759	pfam16729, DUF5067, Domain of unknown function (DUF5067).	7.52663e-06

>NZ_CP012288.1|WP_046871521.1|623012_623693_-|noncanonical-pyrimidine-nucleotidase,-YjjG-family
MKYQNLLFDVDDTLLDFHAAENQALKALFAEIKYPLTDDMVTYFRALNEHMWQRFELGQLDRQTLVNTRFTKLFAHFNETVDGIKYEQIYREFLNQGHQLEPHALELLNSLKDQFNLFIVSNGIGSVQQHRLNDSGLSTYFKHIFVSEEVGYQKPRIEFFDFIANHISGFTPKNALIIGDSLTSDIQGGANAGIDSVWFNPALQPNHSSVSPTYQIDDLLDLKEIL
>NZ_CP012288.1|WP_046871520.1|622377_622830_-|MarR-family-transcriptional-regulator
MEKHLGINRQIHVLANCSTRKFNESFLDDDITGKQGGVLHFLLMRAGKQKIYQRDIEEHFGIRRSSVTSLLQKLEDNGYITRESVADDARLKLIVLTPKAMAFQKSVVQGTIDFEARMLQGVSEDEIATWQKVTQQMTRNLKDKKIGSDK
>NZ_CP012288.1|WP_046871519.1|620641_622378_-|ABC-transporter-ATP-binding-protein
MLKRIGHSVREYKKYALISPILVAIETFIETFIPYLMSKMIDKGIIPGNLAYIEKLGVFMLIGTFISLAGGAGASWYSSKASAGFAKNLRHDLYHHIQDFSFEDVDHFSTSSIVVRLTTDIMNIQQAFQMLIRAAARAPLMLIFSITMAFTVDAQMAMVFVVSVPLMAIGLTVIIAIGRPLFKKVYQRYDGLNRVVRENLRGIRVVKTYNRAELEDKKAEKASSSIYEVFSKAERILQLNSPIMQFVMYGTLLFLAWFGAKRIVGGTMQTGQLVSLLAYAMSVLMSLNILSNVFNQMTISLASAQRIDEVLTYKSTLTNPKNPLTDVKTGEIDFDHVDFAYADDGVTRLEDINLHIKPGETIGIIGETGSGKSSLVQLIPRLYDVSHGSVKVGDQDVRDYDIRTLRDNVSMVLQQNVLFSGSIADNLRWGDEQATDEQLVQAAKLAQADDFINSLPDGYDTYIEQGGSNVSGGQKQRLTIARALLKNPKILILDDSTSAVDTHTDSLIQTAFREELPEMTKLIIAQRISSVQGADRIVVIDQGKIEAVGTHDELMNSDDLYQDIYNSQIKGGETHAKN
>NZ_CP012288.1|WP_056986319.1|618759_620655_-|ABC-transporter-ATP-binding-protein
MQRTRVAGRAKLDGSAWQILWRLLKYIMQKSHFALFIAFFSVIVSAGASVVGTLFIQRLIDDYITPLMKVAHPNFTPLLHMIILMGAIYLLGVIGTLLYSQLMIMTGQKLQKRIRDEMFTHMQQLPLSYFDSNDYGDVMSRYTNDVDTLRQMVEQSFPMFINALFNVVFTLTAMITLSPTLTIISLIVFALSIFIVRKLSSKSSYYFRMQQKALGNIDGYIEEMLNGQKVIKVFSHEDQAKAGFDKRNEALRQDASMANGLSTMLFPIMGNVGNILYVLIAVVGGYFAVNHITPITLGEIAAFVQLSRSFSQPIAQITMQLNSIIMGLAGAQRMFQLFDEPVEQDSGDTTLVYVTENEQHELTETSERTDKWAWKTPEKDGNVKLTPVKGHIEFKDVSFSYDGKKTVLHHISLDAKPGEKMAFVGATGAGKTTITNMLNRFYDISSGQILYDGIDIQNIQKASLRLSMGIVLQDTNLFTASIRDNIRYGRLNATDEEAVEAAKLANADSFIRNLPKGYDTVIDGSGSDLSQGQRQLLSIARAAIADPPTMIMDEATSSIDTRTEALVQSGMDNLMKGRTTFVIAHRLSTIHNSDEILVIEDGRIIEAGNHESLMQEKGEYYELYTGKTILE
>NZ_CP012288.1|WP_062904288.1|617007_618213_-|IS110-family-transposase
MEIIFGIDVSKHSSNVAILADDSVIKEFKITNDRIGYETLDDALNSFKSPKVIFESSGIYSRSIRAFLQRKNWIYTEINPLAAKKDMDGFRHNKNDQLDAVALATAMAHYHYQSTFREAGVYEELHDLERTYQEFNEDLVRAKNRLHKNLQLTFPEVEQFISTTDGTLYWHVVQQFPHPTFVLETKLSELAQLILKATLKNMSEKRALGLAEHLKELANKSAPAVSSDACAVSSVVYLAGEVERLNDKKDEIIREMSQISVSLNEIPILQSIPGFGIKTAVCLLAELGDISRFHSSNAINAYIGIDLIQYQSGDYEMGQHIRKRGNSYARKILFKAVLNMVCAAKYHPSNVSILYQRKKQSSSETHTKKIAIAAMGRLIRTIYHLIKNNELYDSRKCLPQH
>NZ_CP012288.1|WP_046871517.1|616147_616471_-|hypothetical-protein
MIQIPQDMTEVKVKIAQLEELGHKSNEKQVVFDAIQDNAQAILDEQLEGHYDSCTLDNDKITIYETPEKPIGSVKSQGASFEEDFRKNANNMFIYLQQEISKVINQR
>NZ_CP012288.1|WP_046871516.1|615312_616131_-|HAD-family-hydrolase
MSIKLIASDIDGTFLDDQHEFDRTRFQNQLDEMNRRGIHFVVASGNQYLHCTKVMTGINGDLTYVAEDGALIVEKGKMLDSSPIEPELWQKVVTSVDEQPILANAVIILSGEKAAHTNVTPQNEVWGRTGYFYENLTHASDFSTVTDEIYKVDVNWPDLADIRDKYNVLTTEFGNQLTEVMSGYSGIDIIKPHVTKAYGLVQLQRIWNVSMAETMTFGDNQNDAEMLKHAKYGYAMKNASPEAKAATSLVTPLDNNHSGVLDMIDRVLNDQI
>NZ_CP012288.1|WP_062904581.1|613818_615066_+|ISL3-family-transposase
MQMSLTNPILCLFEITDPNLIVTGISKERCSTNQRIHVVHATLSYQLLKCPHCGHKSLIKNGTHMSHLRLGTLSGGRYEMHLKRQRYQCKDCSKTCGAKTKLVNRNETFTHNIKHQVIVLARDMLTSKEIAKLCGISPSSVQRILNANIHLAYRVKHLPENLCFDEFRSCNHWMSFNCCDAVSHRRIVTLKDRLSKDIIDYFEARFSVQERAQVQSVTIDMNAEYGSFIHRLFPNAATIIDRFHIIQLAGRALDNERTQTIRTIQDKHSRIYHILKSQWRLFHLDEIKVNDSKAVYLRGINEYMTQQNAIDLALDAFPRFRSVYQTYQGILSAIHQKDANAFQSLLTNYQPTSNQMDITINTFIKNGSALLNSCRYPFSNGPIEGLNRKIKALKRNCFGFRNIDNFFIRISLIHE
>NZ_CP012288.1|WP_046871515.1|612464_613547_-|hypothetical-protein
MNGKRIKTVILATLAMLALTACRSQDQKRSSSKATTSVSRSATKVSKRKTVKTSDTTSQSSSSAKESAPKTNTMNFDQIKQGNYGSLQGTWTETGHSASKDGQAVEKGGTDTLTVSNGTITNGSTKVQKQTLTDAAGEHSLVFKTKDDVLTANLADEDVAINWMVTFYPKGTTNKYKTNNDSGKNSQNMIVVWTSNNSYTEIFAQTSTTPSVSKTANAAKTTKATKPVETGLNLAQISRNNFSSLVGTWKNTDGKTIIVTNEVKNKPTGSNVAYSKGAVVKGTDGNGHSRVITAGKVTSGYIQGGIGTFDSDAAVSAFDPLTIIPKNVKLSDADDSDSTRDRLILGGGQGGYATQAYYKE
>NZ_CP012288.1|WP_046871514.1|611453_612011_-|DUF5067-domain-containing-protein
MKKKNEAGTATKKRPIYKRIWFWLLVLIMIGGIGAIAGGSGNDSSENQADSKTEKQSESTADKSHKVGDEATVGKVSYKLNSVETTDERNEFEDTNPKNVVVAKYTVTNNSDEDVPVGTDLDVYGSDGKKLKSYAVSDNTLDSVASGKKADVEAAYGVDELGNIELHFSPLASFDDAVKFHTTVE
>NZ_CP012288.1|WP_046871522.1|624072_624261_+|hypothetical-protein
MGDLTKLAEEIINYQKKHDLTDASIAFGTHLSVEKIHNIKINKYNATEDDIRRINDYMRDNK
>NZ_CP012288.1|WP_046871523.1|624480_624981_-|O-acetyl-ADP-ribose-deacetylase
MAFKVIRGDITTMKVDAIVNAANTTLLGSGGVDGAIHRAAGPELLAACRLLHGCQTGEAKITPGFKLPAKFVIHTPGPIWRGGHQHEAELLHNSYQNSLNLADQNHCVSVAFPSISTGVYRFPLQAGAKIAVTTIREFLKTAQSVKDVTMVCFDEGTYQAYLEVQK
>NZ_CP012288.1|WP_046871524.1|624993_626160_-|hypothetical-protein
MDSVLYDLEFAKNDQRLANVFPKEQETFYTGFVNSIGADGVILNTYDDTGQADGAVYVQFDAIENVEFDSPDLDNMLETIQIAENDQLFTVMDRIPDFVSTSDLIKQVVEDAYKNEQFLVLTRSDLENYQEGKVTAVHENDFEMHLVDKFDLTHEVLTTIKYTEAEIVEFSGRELAVETATWPEIAKQQPESRLTLTDTKDFYAVLKNAEQKQELITINDETKSSNFFVGTVNAVNKSEVLCNLVDMAGQFGGYSLIRLDAIVSITLKSDYMQVMEAFINYQKKNQTFVQPVLNEERLFDATDDLIMALIKQTETFSRVLSISLLTGAREMGYITDVTTDTFRFHVIDADLYVDQTGIEIVIEDVDELSFDFLNAVLIENHLRDKGLL
>NZ_CP012288.1|WP_062916563.1|626171_627365_-|MFS-transporter
MDDRTKQTFSWPLFLSPFVSRLGDALFVFGLNWFIVRATGHASLLGIVQGIGGIVLVAGDLFAGPLVDKYNRKLIMLLADIVSFLACLIMAGIMDVNKPVFYQLVLLTCIIDIGLAFNFPAAKAVVPEIIRSDKLSTFNSWSNTGLTLADIVAPLFGGFLLTLHWINFRSFLFINALSFLLSFIFTLALKYKPEKDHTKESMPILESLVKGLNYVRNKRDVFRLIIFDAFLAAMYAGYTLLLPYDVDHYYNGDEKLYSYVLSLVAVGGMLGGLSLVLNKHQPRIKTNYQDAFILAIVLILTGIWINYGLLLVSAFAYGFYTSRMSIRMMTIVQNLTDIAFLGRVFSIWFLCFDSMHPLGSFVFGFISDWFNHGTFFVLGGLVLLGLLVVYLMGRNSD
>NZ_CP012288.1|WP_046871526.1|627510_627891_-|iron-sulfur-cluster-biosynthesis-family-protein
MNIKFDSVSADKVQAHLDDNKRLLLTFEDGVGDYSQHAMIHMQVQFTINVVAKDMPTTGYNAVVHSNIGDLLIKDYSTDDLEENMSMKFNTHLGTLQLSGDGGAIDDNVGFIDFTDKNGIKNNPAR
>NZ_CP012288.1|WP_046871527.1|628418_628946_+|GNAT-family-N-acetyltransferase
MEKFEKYRPILTPHFTLDWLTAAKVKDIYALRHDANVAKMSDRDVDSDIQATVDYVNKIMRAIMNNDSLLWGISERKIEKFLGTFCIWNFNDSKTAAEVRFEVLPNQQNHGIMTEILQRMTEFSFNELGLEKLYAVAKQSNTPAITVLKKTGFEIDPTYPGSQNTLSFSLCATTR
>NZ_CP012288.1|WP_046871528.1|628955_629822_-|viroplasmin-family-protein
MAAKKKFYAVAKGKQTGIFTDWNETKPMIDGFPGAKYKGFKTEAEARQWLNDGGVISKTKPTKKVNTAQSHQANDTEIIVYTDGGSRNTGNVNGGHVKKQDKAAWAYLINVAGKQISDSQGEFGATNNRMEIMALLRALEWLVENQKQTDEISVVTDSQYVLNAIQKHWLAGWKRRGWKRGSGQPLANSELWRQLDGLLPKFSHLQFYWTKGHATNEGNVFVDHLLNQTMDKMSGGQVANKAIRASSPAQTASKLTKKAQKKSVPTSETQKSLDAIKKSLEKLEWYND
>NZ_CP012288.1|WP_046871529.1|629963_630146_-|hypothetical-protein
MRFGNFSNRDYRIALDTETQLFWASEKNDPSIKASGVTITEALDKLNEKTNGLVQQQYAN
>NZ_CP012288.1|WP_046872291.1|630432_631800_-|ISLre2-family-transposase
MYILADFIESLGNLDSLFDLEEQVILHLRKSFQLVVAEYLRQLDETLVPSIPAENTFINRQARTIEFMFGAVNFERRCYLRPNGSYYFPLDEQLQLEERKRISPYFKSVVAKIGQTTTMRNTAAMINLASQTDISAWSVDRIIRDMADTVKTEEKSSEEKLVKKRKVENLVVEGDAFEIHKINRRRQDVHHYIVFESGLDGTRSNKVEFVGINQKKVQKRVTDYIEKYYKISEMTVFTASDGGPGYNPKSMREIVPSAQRVEFTIDRYHFVKKIKQTFGLFNPLVDKAVKSVSLYDQNQLNVILDTFESQIKTDKELESLRVLRQYLARNWQFIKSPHDRGFMRVGKLGSVESSHRAYTYRMKKQGKVWSEKGLEAMLKLIEARVNGKLDKYLRGGLRKLQELTIEIATESLKTLSSAQLSNKHHSKHIGVLSGKIPVDAPTSSPIGAMAKIFSN
>NZ_CP012288.1|WP_046871530.1|632101_632353_+|hypothetical-protein
MRKIFTLSIIGVVLVGLVFLTLSSCGDHKASFDTSTVGSSKQDSTYGAWWEHMWSLPDKNSSNKKNNPRKNSVTKFSNDDNKK

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Crispr_ID: NZ_CP012288_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012288_2

1173473-1173698

Orphan

Consensus_repeat	Method
AGGCAAAGACGGGCGCATGCGGGATCGCAATCCCGCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP012288_2

>merge|NZ_CP012288|2|1173473-1173698|PILER-CR
CGGATGCGGGATCGCAATCCCGCATCCGTCACGCTTGTGATTCTCTTTTTGACTTGTCGAGCTGTCCTAAGACTCGGCGGAAAGCAGCAGGCAAAGACGGGCGTATGTGGGATCGCAATCCCGCGAGAGTCGTGCTTATGATCAGCCTCTTGTTTTACCGAACTGTCCTAAGACTCAGCGGAAAGTAGCAGGCAAAGACGGGCGCGTGCGGGATCGCAATCCCGCG

>NZ_CP012288|2|1|1173473-1173698|PILER-CR
CGGATGCGGGATCGCAATCCCGCATCCGTCACGCTTG	TGATTCTCTTTTTGACTTGTCGAGCTGTCCTAAGACTCGGCGGAAAGCAGCAGGCAAAGACGGG
CGTATGTGGGATCGCAATCCCGCGAGAGTCGTGCTTA	TGATCAGCCTCTTGTTTTACCGAACTGTCCTAAGACTCAGCGGAAAGTAGCAGGCAAAGACGGG
CGCGTGCGGGATCGCAATCCCGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012288.1\|WP_046871028.1\|1162393_1163035_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_003555353.1\|1178515_1179739_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NZ_CP012288.1\|WP_046871033.1\|1170331_1170889_+\|ECF-type-riboflavin-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|184218
NZ_CP012288.1\|WP_056986021.1\|1165267_1166920_-\|alpha,alpha-phosphotrehalase	unknown	unknown	gnl\|CDD\|274115
NZ_CP012288.1\|WP_003555349.1\|1177768_1178506_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|180607
NZ_CP012288.1\|WP_081213089.1\|1176552_1177692_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP012288.1\|WP_046871032.1\|1168389_1169907_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273919
NZ_CP012288.1\|WP_046871031.1\|1167876_1168371_+\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|376324
NZ_CP012288.1\|WP_046871030.1\|1166932_1167649_-\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NZ_CP012288.1\|WP_052694578.1\|1174863_1175754_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP012288.1\|WP_046872521.1\|1174466_1174700_+\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP012288.1\|WP_062904288.1\|1163546_1164752_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP012288.1\|WP_046871027.1\|1161620_1162217_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_062904507.1\|1170893_1172603_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP012288.1\|WP_046872520.1\|1174199_1174406_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_155387016.1\|1173858_1174017_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_046872497.1\|1180478_1180694_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_046872216.1\|1180803_1181139_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_056986019.1\|1175755_1176523_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378937
NZ_CP012288.1\|WP_046871035.1\|1172595_1173429_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692

Protein	Function_ID	Function_description	E-value
NZ_CP012288.1\|WP_003555353.1\|1178515_1179739_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.70068e-42
NZ_CP012288.1\|WP_046871033.1\|1170331_1170889_+\|ECF-type-riboflavin-transporter-substrate-binding-protein	gnl\|CDD\|184218	PRK13661, PRK13661, ECF-type riboflavin transporter substrate-binding protein.	4.32555e-79
NZ_CP012288.1\|WP_056986021.1\|1165267_1166920_-\|alpha,alpha-phosphotrehalase	gnl\|CDD\|274115	TIGR02403, Trehalose-6-phosphate_hydrolase, alpha,alpha-phosphotrehalase. Trehalose is a glucose disaccharide that serves in many biological systems as a compatible solute for protection against hyperosmotic and thermal stress. This family describes trehalose-6-phosphate hydrolase, product of the treC (or treA) gene, which is often found together with a trehalose uptake transporter and a trehalose operon repressor.	0
NZ_CP012288.1\|WP_081213089.1\|1176552_1177692_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.9929e-31
NZ_CP012288.1\|WP_046871032.1\|1168389_1169907_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273919	TIGR01995, beta-glucosides_PTS_EIIBCA, PTS system, beta-glucoside-specific IIABC component. This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.	5.13755e-132
NZ_CP012288.1\|WP_046871031.1\|1167876_1168371_+\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|376324	pfam00358, PTS_EIIA_1, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1.	1.3589e-54
NZ_CP012288.1\|WP_046871030.1\|1166932_1167649_-\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	6.03968e-100
NZ_CP012288.1\|WP_046872521.1\|1174466_1174700_+\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	7.47555e-13
NZ_CP012288.1\|WP_062904288.1\|1163546_1164752_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	8.98508e-26
NZ_CP012288.1\|WP_052694578.1\|1174863_1175754_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.0313e-71
NZ_CP012288.1\|WP_062904507.1\|1170893_1172603_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	7.8648e-82
NZ_CP012288.1\|WP_003555349.1\|1177768_1178506_-\|ATP-binding-protein	gnl\|CDD\|180607	PRK06526, PRK06526, transposase; Provisional.	8.58859e-69
NZ_CP012288.1\|WP_056986019.1\|1175755_1176523_+\|ABC-transporter-permease	gnl\|CDD\|378937	pfam12730, ABC2_membrane_4, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	9.90841e-07
NZ_CP012288.1\|WP_046871035.1\|1172595_1173429_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.73154e-34

>NZ_CP012288.1|WP_046871035.1|1172595_1173429_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MNNNVLIGYKQRDNFVDRLTGTTKLIGLIALSVIGMTSFDTRFLLVLTVCSLALFRVSGIKFHEVSFILGFITVFSVLNLIAVYIFGPKYGVHLYGSEHVIWQGIGPYNLTWEQLFYEFNLFLKYIFTVPLALIFLMTTNPSEFSSSLNRIGISYRISYAVSLALRYIPDVQNDYRQISRAQQARGNEISKKGKLTHRVKVAGQILLPLIFTSLDRIETISQAMELRRFGKLKKRTWYAARPMKRNDFLALIVIALVVLVGIYLFKVNGGRFYNPFK
>NZ_CP012288.1|WP_062904507.1|1170893_1172603_+|ABC-transporter-ATP-binding-protein
MNNPIISFQDVSFQYQSQSEPTLNHLNFDIYAGEKVLIAGPSGSGKTTISRLMNGLIPSAYPGKLSGKILINGQSVTDQTIFDLSLKVGTVLQDPDTQFVGLTVAEDIAFALENDGEKQSVLKQKASEWAKQLGISEIINNHPQEISGGQKQRVAMAGVLVDEGKILLFDEPLASLDPVAGRESIELIDEMQKKGDTTTVIIEHRIEDVLYKSVDRIILVDEGEIVANDTPDTILKSGILAKLGLREPLYLSALKYAGVDLKQVAHVDNVNDVALTENTVAAVKKWVQPHHSQTLATDQEPVLKAKDISFSCDSKQVLNKLNLSIQPGEMVSLVGRNGVGKTTLSNIITGFLHQSSGSLTLNGKVMDDDSIKERADHIGYVLQDPNMMISKNTVSEEVALGLTLRQVTPDEIETRVAETLKVCGLFEYRHWPISALSFGQKKRVTIAAILVLNPELLILDEPTAGQDWRHYTEMLTFIRDLNQKTGISVIFITHDMHLMMEYSDRVVVLNDGVIAYDDQPMKLFANLDLLKQASLVETSLFTLAQRVKVDPEDLIASFIDQERVGQRDE
>NZ_CP012288.1|WP_046871033.1|1170331_1170889_+|ECF-type-riboflavin-transporter-substrate-binding-protein
MHKKQGISVRTVVAIGIGTAIFFVLMRYIPIPTGVPDTNINLAYGFLALMGSIFGPVAGGLIAFLGHMFNDLTWGEPWWTWIVADGIYGILFGLTKKYLNIENGGLTKHKLVIFNVYQIIISVLVWGIIAPTGDVLVYSEPASKVYLQGITSVICNALSVGILGTILLVAYARTRSKKGSLKKES
>NZ_CP012288.1|WP_046871032.1|1168389_1169907_+|PTS-transporter-subunit-EIIC
MAKKDYTKLASDIIENIGGKENVKSLIHCITRLRFYLKDESIAKDDVIKNLDGVIDVRHAQGQYQVVIGAAVTDVYDAVIAQLGQEFADPDATEAAVQETKAAAGSAKEPDNRSFGQKIKDGFNALIGVITGSMMPVVGLLAASGILKGLLQMAVDFHWTVPTSQTYIIISAMGDSAFYFLPIIVGFTAAKRLKSDPVIMAIIGGVLVYPSLFSIATGTKTTGTFLGMALNTNLFGLPIHMVNYTYSIFPIIAGAWMAHYIEIWLKKWIPQILQMIFVPLFEVIIVSAIIIIFVGPAITLVSTGISWLLDAILKFNYPIAGLIIGGFYQSLVIFGLHWAIVPLIANDIASKGYSYLNAIVSMTMVAQGAAVLAIFLKSKIASIKELSGAAAISAFVGITEPSIYGINLKYGRAFLTASIGAAAGGLVSGLLNVNMYGFTGSIIGFPSFFTPAKFGGGMSNEINFWIATAVTLVVAFGCTWAFGFKDADVAAEKKVVRRKTIGKDA
>NZ_CP012288.1|WP_046871031.1|1167876_1168371_+|PTS-glucose-transporter-subunit-IIA
MFGFGKRKKVATDNAIYAPVTGQVIDLSKVSDPVFAQKAMGEGLGVKPSDGKIVSPVAGAVTMVAGTKHALGFTMANGLEVLIHMGVDTVDLKGAPFTVSVKPGDIVNGGDAIATIDLDQIHDANLDDVIIVVFTNSADKLDHLDVTTGETTAKAKIGMVTVKA
>NZ_CP012288.1|WP_046871030.1|1166932_1167649_-|trehalose-operon-repressor
MRNKFNAIYQDLADKINHHNYPVDSYLPSETQLSELYGTSRETIRKALSELLTNGFIQKIRGKGSIVLNLQRFNFPVSGITSFKELNNSLHMNSTTEVLCLEDQHVPLEKFDYQSSSPLLATYVERLRKTNNEPIVLDHDYILKSVVPEISHKVAADSLYDYFENQLGLTISYATKKITVESPTKEEAQLLELNEHQDVVIVRSQTYLEDTTLFQFTESVHRPDKFSFVDFARRQKIN
>NZ_CP012288.1|WP_056986021.1|1165267_1166920_-|alpha,alpha-phosphotrehalase
MSFQNKIIYQIYPKSFYDSDGDGIGDLQGIIKKIPYLVKLNIDMIWFNPFFVSPQNDNGYDIADYCKVDPRFGTMADFDELARKLKENHIGIMLDMVLNHTSTSHEWFQKALAGNKKYQAFYYIRDPKPNGDLPTNWESKFGGPAWAKFGNTGKYYLHLYDPSQADLDWHNPEVRQALYKVINFWRAKGVHGFRFDVINVTGKEEKLIDAPTNVASKTLYTDTPIVQDYLKEMNQASFGQDPDAITVGEMSSTSIANSVQYTLPGNHELSMVFTFHHLKVDYVNGEKWSKMPFDFMKLKGILNEWQSGMAKGGGWNALFWNNHDQPRAINRFGDPIHYRAKSAEMLATTMHLLRGTPYIYMGEEIGMSDPDYTSMSDYVDIECKNAYQELLNAGKSPSEAFEIIKTKSRDNSRTPMQWNNSKYAGFSTHKPWLMPTNQAKVNVQDELDHGEIFTYYQKLIKLRKTMPIISEGNFKPLLENDHQVFAYLRTYRNQTLLVLNNFYGKATTVQLPSEMTKLHGKVLISNYDESIELQDQLELKPYQSVAFLLN
>NZ_CP012288.1|WP_062904288.1|1163546_1164752_+|IS110-family-transposase
MEIIFGIDVSKHSSNVAILADDSVIKEFKITNDRIGYETLDDALNSFKSPKVIFESSGIYSRSIRAFLQRKNWIYTEINPLAAKKDMDGFRHNKNDQLDAVALATAMAHYHYQSTFREAGVYEELHDLERTYQEFNEDLVRAKNRLHKNLQLTFPEVEQFISTTDGTLYWHVVQQFPHPTFVLETKLSELAQLILKATLKNMSEKRALGLAEHLKELANKSAPAVSSDACAVSSVVYLAGEVERLNDKKDEIIREMSQISVSLNEIPILQSIPGFGIKTAVCLLAELGDISRFHSSNAINAYIGIDLIQYQSGDYEMGQHIRKRGNSYARKILFKAVLNMVCAAKYHPSNVSILYQRKKQSSSETHTKKIAIAAMGRLIRTIYHLIKNNELYDSRKCLPQH
>NZ_CP012288.1|WP_046871028.1|1162393_1163035_+|hypothetical-protein
MQHRYLKMLIYFCVWMGLNILWVLRSISYPTVDSTMLVGKSIALHFAPIVGITVLLLMTLFKWRPLNLVALIWLVLATITARPPIYLLSVGMFGGILVLICDVYLTVIICNHDQPVKYVNQIAVILGIAFFLCLLSPKLSAQFASSGYSDPVTATKTEITVTKKNTNQLKTNNVTRITPRHPKIYLNGVGDINLKIRRIGIFYFSYADYVYKW
>NZ_CP012288.1|WP_046871027.1|1161620_1162217_+|hypothetical-protein
MHKIPSTAFAKAGIYEKEKVDYIKKCFTPMRVSINDQIFPRSQKNSDKESHKIGREIFGLATPETIEFNDTEIRVIDKDKKVVETTKATDVQYIQFGVIRRMTTYMWSPGFYYELTMTLGTSSGNYYLLNGDFAVYEQLKAWGEKQNIEIEDPFELASITTDAHVFGAGDPSTWGTLLDKTFITKVAKVADLNYPEEV
>NZ_CP012288.1|WP_155387016.1|1173858_1174017_+|hypothetical-protein
MKYENKTKTDNQVLKTIQPDKSMEAGMRLLAQLKKAEKGSFHSLEEVRHKLF
>NZ_CP012288.1|WP_046872520.1|1174199_1174406_+|hypothetical-protein
MEKNWLKTAVSVTMSGEGHEEGLKRSFGNMPETVTDDQIKGLGSVLEAVSKDKFDFATVTTTEKVVNN
>NZ_CP012288.1|WP_046872521.1|1174466_1174700_+|DUF2922-domain-containing-protein
MKQLDMEFVSSLGKVRHIKLKYVSEDLEPAAVKTAMTQLAGLKVFVKDDEELYAQPQAAKYIETINTPLFDDKAVKA
>NZ_CP012288.1|WP_052694578.1|1174863_1175754_+|ABC-transporter-ATP-binding-protein
MNDFLKVKHLNMKIGKRKILKDINFSCRKGHITGLIGPNGAGKTTIMKCILGLYPYHKASIILNGTDIKSSNILNVGIGALIENPSIYPFLTGTEHLVMYAKDKNCIEDIVQALKMQSFINKKSKDYSLGMKQKLGIAIALLDNPQLIILDEPMNGLDPSSTYLLRNLLLKLAKQGITILISSHILSELEKIIDDVVMINNGKVILNVSKNKLEQQSQSTLFLSTNHNDKALKVLLEQGFKAQESNGMIKAFNISSSNLNELLAVIINNDIRLLGLEHKENGLEDTLLKLIESENN
>NZ_CP012288.1|WP_056986019.1|1175755_1176523_+|ABC-transporter-permease
MSSLINQEIYKLCHKKTVQFTPLVLFLAMLVVGIITKNGSDNRFYIEAGYAGFQWITIILIIECASMVAMEFQYGTIKHLIYESNNRMKIYLSKLLTMFLYDVLLHIFTLVFTIVIKYLTVGTNVSFSQNYLYHASLFQNLFTNTLVDFLGSLIIVSSVFMMASLMNSSAIAIAVGIGFIFIGEGLSSALISALIKKIPLIKWNPFNMLNIANQWSNPDYFSTTHLTQTQLINGNILYTLIFIVMSFLFFRKKRV
>NZ_CP012288.1|WP_081213089.1|1176552_1177692_-|MFS-transporter
MYETTKNQSLVSILGTISMAAMLLSFIGGYIVDQQSKVNLLRAIILIRCLLVVIGLLLLYLFHSNLKTLFLVVIANSLLSIVYTPLSESIAPVLVENKKELFKANSWVSLANQLASVSSSGLSVLFVLWRKPIWALLGLGLSVLISYLTILHVPADAAPIKKHSLSFRETMSDFKHGLLLIVHNRLISLMIPIALISNFCFWSIWLLMPKYSVDIFNQYKIVYNVIDISFTIGGILGAAAFSKYHGRLKTGIFYPALLVGQSIMLILLGVNAWVKPSIINVFFISILWIGYGIFNSISSVLYFSIIQMSASNDTIGLIIGAVLTIFSLANPIAAALSAPISRLYTLPTIIVIFGSIMLFAALVVFSPYFNKELAKYDKK
>NZ_CP012288.1|WP_003555349.1|1177768_1178506_-|ATP-binding-protein
MTTNNQILLNNLERLGLNKIREYLPNYLDQIHTDNLSLTEALIDLTNSELQNRHEGQIARAIGRARFPNTKSLDTFDFSFQPSINRQEVLEFQNLAFMEKSENLIFIGNPGVGKTHLAISIGIEACKQGCRVLFINCHELLIRLRAAYEKGLLDRSLSRYSRYDLLIIDEIGYLPIGHQEANLLFQLVNARYEKHSTIITSNSDLSAWVDIFQNPTVTAAILDRLVHHVHVVKITGKSYRLRGLK
>NZ_CP012288.1|WP_003555353.1|1178515_1179739_-|IS21-family-transposase
MRRDLREGVTIYVTENIKPNFAEIARQYNVDYRTVKKAYEEVKAGLKGRPSGRPKRPSLLDPFKQTIDSKLELNCSAASIFKFIQKKGFTGSYTLVKDYCRQTRRERVKKATIRIEHSPGLSAQVDWKEEMALVSSEGELFKFNIFLYVLPYSKLKYMTLTFDRSQDTLFSCLHDAFLHTGGIPTEIWFDNMKTVVDHTKSQFGHAVFNERFHEFCKDAGFTPIACRPFRPQTKGAVEALARTVERLRPYNTEFADGTELIELVHMLRDDLNHETSQATDEVPYLKWLDEEKEYLHRVPVNLLEPYFEENITRVVSKEAMINFRKCKYSVDPRYIGCTVAVEISNDEQRIHIYYNGEEIRTHSITTNSLNYDPQDQFNILKSDLLKGRTDEDISAYIREHMTDYDNL
>NZ_CP012288.1|WP_046872497.1|1180478_1180694_+|hypothetical-protein
MADFAEKTALLDTATKDIFDWSDDATPLRDAMWDKVMESNSHNTDATSEQAAKWEDMNDSDLKAAAEKLLK
>NZ_CP012288.1|WP_046872216.1|1180803_1181139_+|hypothetical-protein
MNKLKTKYDVYRYTGIPVVKDASGNYKFKLDDMGHVKPHSWRTGKHTKGKFKQRGQVFLTENRLFIAVITAEKMSFNQRHSVTPLQRFTSETINESLLKTGTELVRNLQDD

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Crispr_ID: NZ_CP012288_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012288_3

1234031-1235322

TypeII

Consensus_repeat	Method
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	PILER-CR
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CRISPRCasFinder
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CRT

19 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP012288_3

>merge|NZ_CP012288|3|1234031-1235322|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGTGATACCAGTGCCGTTTAACGCTGACATCGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCACTTTCCAAAAGCCAAGAAAGCTGGTTGAAAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCACTTCCACATTTTTGGCACCATCAAACGCAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCATAAAACATGATAAAGACGTTCAGCATGAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTATTATATGCAGATCCTAATGTTGAACTAAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCACTGATTAGTTTGGTCTCACAATCCAAGCGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCACGCAAGACCAAATTGATTCTGGCCCAGCAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCATGGACGTTCATGTATGGCTCATTCTCAAAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGCCCGTTTGGGTTTGGCCTTGAACATAATCGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTGTATTACAGGGTTTACATTGCCTACGCGGGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCAAAAGTTTGTGCTGCCAATGGCAGGAACGTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGATCCATTAACAATCGCAAACTCACCATTTCCTTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGTTTGTCCGAACCGTGCGTCATGCACATCTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTACTCAATCGCAAATTGATTCCGCACCGGAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCATCTTATCTGGCATTTCATCACACATACGTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCTGACCATAAAGCTGTATCAGCAACCACCAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCCGGTCGTCGTCGGTTAAGTACCACTCATGGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGTGTGGCGTTGGCTAACGTTGTTGAGGGCAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTAATGTAAAAAAGCTTGACTGTATACACATGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGGAA

>NZ_CP012288|3|2|1234031-1235256|PILER-CR
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGATACCAGTGCCGTTTAACGCTGACATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACTTTCCAAAAGCCAAGAAAGCTGGTTGAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTTCCACATTTTTGGCACCATCAAACGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATAAAACATGATAAAGACGTTCAGCATGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATTATATGCAGATCCTAATGTTGAACTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTGATTAGTTTGGTCTCACAATCCAAGC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACGCAAGACCAAATTGATTCTGGCCCAGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATGGACGTTCATGTATGGCTCATTCTCAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCCGTTTGGGTTTGGCCTTGAACATAATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTATTACAGGGTTTACATTGCCTACGCGG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAAGTTTGTGCTGCCAATGGCAGGAACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGATC	CATTAACAATCGCAAACTCACCATTTCCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTTTGTCCGAACCGTGCGTCATGCACATCT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TACTCAATCGCAAATTGATTCCGCACCGGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATCTTATCTGGCATTTCATCACACATACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTGACCATAAAGCTGTATCAGCAACCACCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGGTCGTCGTCGGTTAAGTACCACTCATG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGTGGCGTTGGCTAACGTTGTTGAGGGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC

>NZ_CP012288|3|2|1234031-1235322|CRISPRCasFinder
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGATACCAGTGCCGTTTAACGCTGACATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACTTTCCAAAAGCCAAGAAAGCTGGTTGAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTTCCACATTTTTGGCACCATCAAACGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATAAAACATGATAAAGACGTTCAGCATGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATTATATGCAGATCCTAATGTTGAACTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTGATTAGTTTGGTCTCACAATCCAAGC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACGCAAGACCAAATTGATTCTGGCCCAGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATGGACGTTCATGTATGGCTCATTCTCAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCCGTTTGGGTTTGGCCTTGAACATAATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTATTACAGGGTTTACATTGCCTACGCGG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAAGTTTGTGCTGCCAATGGCAGGAACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGATC	CATTAACAATCGCAAACTCACCATTTCCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTTTGTCCGAACCGTGCGTCATGCACATCT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TACTCAATCGCAAATTGATTCCGCACCGGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATCTTATCTGGCATTTCATCACACATACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTGACCATAAAGCTGTATCAGCAACCACCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGGTCGTCGTCGGTTAAGTACCACTCATG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGTGGCGTTGGCTAACGTTGTTGAGGGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TAATGTAAAAAAGCTTGACTGTATACACAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGGAA

>NZ_CP012288|3|1|1234031-1235322|CRT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGATACCAGTGCCGTTTAACGCTGACATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACTTTCCAAAAGCCAAGAAAGCTGGTTGAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTTCCACATTTTTGGCACCATCAAACGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATAAAACATGATAAAGACGTTCAGCATGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATTATATGCAGATCCTAATGTTGAACTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTGATTAGTTTGGTCTCACAATCCAAGC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACGCAAGACCAAATTGATTCTGGCCCAGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATGGACGTTCATGTATGGCTCATTCTCAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCCGTTTGGGTTTGGCCTTGAACATAATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTATTACAGGGTTTACATTGCCTACGCGG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAAGTTTGTGCTGCCAATGGCAGGAACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGATC	CATTAACAATCGCAAACTCACCATTTCCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTTTGTCCGAACCGTGCGTCATGCACATCT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TACTCAATCGCAAATTGATTCCGCACCGGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATCTTATCTGGCATTTCATCACACATACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTGACCATAAAGCTGTATCAGCAACCACCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGGTCGTCGTCGGTTAAGTACCACTCATG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGTGGCGTTGGCTAACGTTGTTGAGGGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TAATGTAAAAAAGCTTGACTGTATACACAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012288.1\|WP_056986236.1\|1222551_1223055_-\|transcription-elongation-factor-GreA	unknown	unknown	gnl\|CDD\|234693
NZ_CP012288.1\|WP_063510373.1\|1236619_1237435_+\|DUF1275-domain-containing-protein	unknown	unknown	gnl\|CDD\|377734
NZ_CP012288.1\|WP_046871859.1\|1223407_1224409_-\|zinc-binding-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223677
NZ_CP012288.1\|WP_046872291.1\|1230646_1232014_-\|ISLre2-family-transposase	unknown	unknown	gnl\|CDD\|284250
NZ_CP012288.1\|WP_046871854.1\|1232145_1233048_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP012288.1\|WP_046871857.1\|1225066_1225312_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_046872091.1\|1237922_1238834_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP012288.1\|WP_056985955.1\|1233546_1233933_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP012288.1\|WP_062916645.1\|1245379_1246789_+\|pyruvate-oxidase	unknown	unknown	gnl\|CDD\|213733
NZ_CP012288.1\|WP_056985954.1\|1240479_1241040_+\|UbiX-family-flavin-prenyltransferase	unknown	unknown	gnl\|CDD\|223241
NZ_CP012288.1\|WP_056985953.1\|1241362_1242706_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP012288.1\|WP_046872501.1\|1236005_1236479_+\|CinA-family-protein	unknown	unknown	gnl\|CDD\|334938
NZ_CP012288.1\|WP_046872092.1\|1238981_1240457_+\|UbiD-family-decarboxylase	unknown	unknown	gnl\|CDD\|376697
NZ_CP012288.1\|WP_046871858.1\|1224526_1225009_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP012288.1\|WP_062904505.1\|1226234_1230371_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP012288.1\|WP_046871856.1\|1225527_1226040_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP012288.1\|WP_046872502.1\|1235451_1235913_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225064
NZ_CP012288.1\|WP_046870605.1\|1242927_1243389_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|238182
NZ_CP012288.1\|WP_062904504.1\|1233025_1233283_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP012288.1\|WP_062916642.1\|1243432_1244803_+\|Nramp-family-divalent-metal-transporter	unknown	unknown	gnl\|CDD\|234815

Protein	Function_ID	Function_description	E-value
NZ_CP012288.1\|WP_056986236.1\|1222551_1223055_-\|transcription-elongation-factor-GreA	gnl\|CDD\|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	9.41281e-52
NZ_CP012288.1\|WP_063510373.1\|1236619_1237435_+\|DUF1275-domain-containing-protein	gnl\|CDD\|377734	pfam06912, DUF1275, Protein of unknown function (DUF1275). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although most members have 6 TM regions, and may be putative permeases.	1.62147e-44
NZ_CP012288.1\|WP_046871859.1\|1223407_1224409_-\|zinc-binding-alcohol-dehydrogenase-family-protein	gnl\|CDD\|223677	COG0604, Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only].	9.52511e-33
NZ_CP012288.1\|WP_046872291.1\|1230646_1232014_-\|ISLre2-family-transposase	gnl\|CDD\|284250	pfam06782, UPF0236, Uncharacterized protein family (UPF0236).	1.04753e-29
NZ_CP012288.1\|WP_046871854.1\|1232145_1233048_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	8.74374e-100
NZ_CP012288.1\|WP_046872091.1\|1237922_1238834_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.53013e-41
NZ_CP012288.1\|WP_056985955.1\|1233546_1233933_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	5.4497e-39
NZ_CP012288.1\|WP_062916645.1\|1245379_1246789_+\|pyruvate-oxidase	gnl\|CDD\|213733	TIGR02720, Pyruvate_oxidase, pyruvate oxidase. Members of this family are examples of pyruvate oxidase (EC 1.2.3.3), an enzyme with FAD and TPP as cofactors that catalyzes the reaction pyruvate + phosphate + O2 + H2O = acetyl phosphate + CO2 + H2O2. It should not be confused with pyruvate dehydrogenase [cytochrome] (EC 1.2.2.2) as in E. coli PoxB, although the E. coli enzyme is closely homologous and has pyruvate oxidase as an alternate name. [Energy metabolism, Aerobic].	0
NZ_CP012288.1\|WP_056985954.1\|1240479_1241040_+\|UbiX-family-flavin-prenyltransferase	gnl\|CDD\|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	8.93354e-100
NZ_CP012288.1\|WP_056985953.1\|1241362_1242706_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.13793e-52
NZ_CP012288.1\|WP_046872501.1\|1236005_1236479_+\|CinA-family-protein	gnl\|CDD\|334938	pfam02464, CinA, Competence-damaged protein. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. This Pfam family consists of putative competence-damaged proteins from the cin operon. Some members of this family have nicotinamide mononucleotide (NMN) deamidase activity.	4.91686e-55
NZ_CP012288.1\|WP_046872092.1\|1238981_1240457_+\|UbiD-family-decarboxylase	gnl\|CDD\|376697	pfam01977, UbiD, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase. This family has been characterized as 3-octaprenyl-4- hydroxybenzoate carboxy-lyase enzymes. This enzyme catalyzes the third reaction in ubiquinone biosynthesis. For optimal activity the carboxy-lase was shown to require Mn2+.	7.53053e-130
NZ_CP012288.1\|WP_046871858.1\|1224526_1225009_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.20806e-09
NZ_CP012288.1\|WP_062904505.1\|1226234_1230371_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	7.21804e-145
NZ_CP012288.1\|WP_046871856.1\|1225527_1226040_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	2.0356e-37
NZ_CP012288.1\|WP_046872502.1\|1235451_1235913_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	3.09841e-57
NZ_CP012288.1\|WP_046870605.1\|1242927_1243389_+\|universal-stress-protein	gnl\|CDD\|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	3.17299e-09
NZ_CP012288.1\|WP_062904504.1\|1233025_1233283_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	3.68856e-23
NZ_CP012288.1\|WP_062916642.1\|1243432_1244803_+\|Nramp-family-divalent-metal-transporter	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	0

>NZ_CP012288.1|WP_056985955.1|1233546_1233933_+|type-II-A-CRISPR-associated-protein-Csn2
MFQGQLQKKIVSKLDDDTRLQLTDLNNKLKSLIFDATFSLDLPLKVDSEFDPVKLVKYCNVGFVSALNRDPYDIIETVLKTASELKETKILILTNVRNYLSVSQFNELVSLISTLDLNILFIEFSDNR
>NZ_CP012288.1|WP_062904504.1|1233025_1233283_+|CRISPR-associated-endonuclease-Cas2
MRLMVMFDLPVETSEDRRNYRKFRKALLNEGFLMVQYSIYVRVCVDKKSANLMEKRIATFSPANGLIQSLMVTEKQYNSMNFIVG
>NZ_CP012288.1|WP_046871854.1|1232145_1233048_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVTQHAKISYSGHCVVVQTQDSTNQIPVSDIQILLISTTRAVITSAVISELAKHQSKVIFTDNSGEPVTETMDYYPNNRDPQLLQTQFNWNEERKTSLWTKIIVQKITNQIYVTEALGINAQDLKDELAKLEINDVTNREAVVARKYFSLLFESESSRRNFSPINAALNYGYAIILSAVNREIAANGYLTQLGVHHHSQENDFNLGSDLMEPFRPIVDWWVKQKKFNDFTPDIKFGLVDLLNLKMKYNGQNTILRNAITKHVDNCLKYLSGEIDKIKIEVEISEVSNNAINGHV
>NZ_CP012288.1|WP_046872291.1|1230646_1232014_-|ISLre2-family-transposase
MYILADFIESLGNLDSLFDLEEQVILHLRKSFQLVVAEYLRQLDETLVPSIPAENTFINRQARTIEFMFGAVNFERRCYLRPNGSYYFPLDEQLQLEERKRISPYFKSVVAKIGQTTTMRNTAAMINLASQTDISAWSVDRIIRDMADTVKTEEKSSEEKLVKKRKVENLVVEGDAFEIHKINRRRQDVHHYIVFESGLDGTRSNKVEFVGINQKKVQKRVTDYIEKYYKISEMTVFTASDGGPGYNPKSMREIVPSAQRVEFTIDRYHFVKKIKQTFGLFNPLVDKAVKSVSLYDQNQLNVILDTFESQIKTDKELESLRVLRQYLARNWQFIKSPHDRGFMRVGKLGSVESSHRAYTYRMKKQGKVWSEKGLEAMLKLIEARVNGKLDKYLRGGLRKLQELTIEIATESLKTLSSAQLSNKHHSKHIGVLSGKIPVDAPTSSPIGAMAKIFSN
>NZ_CP012288.1|WP_062904505.1|1226234_1230371_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTNEKYSIGLDIGTSSIGFAVVNDNNRVIRVKGKNAIGVRLFDEGKAAADRRSFRTTRRRLSRRRWRLKLLREIFDAYITPVDEAFFIRLKESNLSPKDSKKQYSGDILFNDRSDKDFYEKYPTIYHLRNALMTEHRKFDVREIYLAIHHIMKFRGHFLNATPANNFKVGRLNLEEKFEELNDIYQRVFPDESIEFRTDNLEQIKEVLLDNKRSRADRQRTLVSDIYQSSEDKDIEKRNKAVATEILKASLGNKAKLNVITNVEVDKEAAKEWSITFDSESIDDDLAKIEGQMTDDGHEIIEVLRSLYSGITLSAIVPENHTLSQSMVAKYDLHKDHLKLFKKLINGMTDTKKAKNLRAAYDGYIDGVKGKVLPQEDFYKQVQVNLDDSAEANEIQTYIDQDIFMPKQRTKANGSIPHQLQQQELDQIIENQKAYYPWLAELNPNPDKKRQQLAKYKLDELVTFRVPYYVGPMITAKDQKNQSGAEFAWMIRKEPGNITPWNFDQKVDRMATANQFIKRMTTTDTYLLGEDVLPAQSLLYQKFEVLNELNKIRIDHKPISIEQKQQIFNDLFKQFKNVTIKHLQDYLVSQGQYSKRPLIEGLADEKRFNSSLSTYSDLCGIFGAKLVEENDRQEDLEKIIEWSTIFEDKKIYRAKLNDLTWLTDDQKEKLATKRYQGWGRLSRKLLVGLKNSEHRNIMDILWITNENFMQIQAEPDFAKLVTDANKGMLEKTDSQDVINDLYTSPQNKKAIRQILLVVHDIQNAMHGQAPAKIHVEFARGEERNPRRSVQRQRQVEAAYEKVSNELVSAKVRQEFKEAINNKRDFKDRLFLYFMQGGIDIYTGKQLNIDQLSSYQIDHILPQAFVKDDSLTNRVLTNENQVKADSVPIDIFGKKMLSVWGRMKDQGLISKGKYRNLTMNPENISAHTENGFINRQLVETRQVIKLAVNILADEYGDSTQIISVKADLSHQMREDFELLKNRDVNDYHHAFDAYLAAFIGNYLLKRYPKLESYFVYGDFKKFTQKETKMRRFNFIYDLKHCDQVVNKETGEILWTKDEDIKYIRHSFAYKKILVSHEVREKRGALYNQTIYKAKDDKGSGQGSKKLIRIKDDKETKIYGGYSGKSLAYMTIVQITKKNKVSYRVIGIPTLALARLNKLENDSTENNGELYKIIKPQFTHYKVDKKNGEIIETTDDFKIVVSKVRFQQLIDDAGQFFMLASDTYKNNAQQLVISNNALKAINNTNITDCPRDDLERLDNLRLDSAFDEIVKKMDKYFSAYDANNFREKIRNSNLIFYQLPVEDQWENNKITELGKRTVLTRILQGLHANATTTDMSIFKIKTPFGQLRQRSGISLSENAQLIYQSPTGLFERRVQLNKIK
>NZ_CP012288.1|WP_046871856.1|1225527_1226040_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MKISVPTSNGLLLDKYSKHAAPEQIYNGNPSISFPIDIQDVPDNATTLALTLLDFDAVPVCGFPWIHWTAVNIPADKSVTIPENASQSNVIDFIQGNNSTAGSLIGATDPLTTRHYIGPTPPDKNHDYWLSIYALDTTLSLQNGFWLNEFYHAAKGHIISKQRLSIISRA
>NZ_CP012288.1|WP_046871857.1|1225066_1225312_-|hypothetical-protein
MLLNSKNLSVLEVQVLGIYQAKIEVKTISGKCLFVYPTQTQKDDPLFWQSLKDIIKAKLWLPINKTLNQLIDSDWLVPLNT
>NZ_CP012288.1|WP_046871858.1|1224526_1225009_+|winged-helix-DNA-binding-protein
MDEKQYQTITQLLKQLSATENHNQHEAWIAKQAAIKENPQKNHLTHNDLDILGVLLQGEKTVSEVVEAVQITQGGTSRRINHLEKLDLLEKFKRPTNKKTVYLKLTADGQKLATAHIALHKHLHEETVQALAEFSDSELAVVTRFLRKLADAQKDFETRY
>NZ_CP012288.1|WP_046871859.1|1223407_1224409_-|zinc-binding-alcohol-dehydrogenase-family-protein
MKALIIKDFKTAPMIDLNVPTPVADTKFDTLIDVLAAPIENFDKANATGRHYSSTYWHPAFPSIPGASGIGRRVDNGKLVAFPARTLKPRFGSFAEQTVANSKLLFEIPEDTDIYSSTAAASSLTTSIAPLQFSLEMKPGNTVLINGATGFAGQLAIQAAKALGAAEIIGTGRNPERLAALKDLGATQTISLADDDETILNNLSNMKIKGDLIILDYLWGHPIELILKSIVPTSLEMKRATSLVSIGAIAGQNITLPSTALRTSGLQIIGMQTPKVMQNQQAVYQAVWKLLGTGKIKTTVKTISLEDAAKDIDWQKPVPSGVRTVIKVSEIKR
>NZ_CP012288.1|WP_056986236.1|1222551_1223055_-|transcription-elongation-factor-GreA
MEAIKLVREATMSEPYFNKITATGYHEIEKEIEELKAKRPALTKRLAAAAALGDRSENAEYTFSKRDLRQLESRLHFLNKQLQYSKIVQPTNNQIVEIGKKVTIEFVDDHDQMDYQLVGKQEADIKTNKISLVSPLGSALLNKTVGDIVTIHAPEETYQVKILSVNL
>NZ_CP012288.1|WP_046872502.1|1235451_1235913_+|GNAT-family-N-acetyltransferase
MQVTVKSFSELSNTELFKIYKLRTQVFVVEQLCAYQEVDDEDLIAQHLQFTNEAQQLVAYLRIIPETNETIVHIGRVVVNPLFRKQGYGRKLITSGLETIKKDMPKVTTVKIQAQAYLRSFYQSFGFKPVSDVYLDTGIPHLDMILELQGNKK
>NZ_CP012288.1|WP_046872501.1|1236005_1236479_+|CinA-family-protein
MDEKLVNYVINTLIEENLSITAAESLTGGLFQSEITTVPGSSAVFSGGFVTYADEVKTQLLSVPKELIQQYGVVSYEVAVAMAQGAQKVLKTDLAISFTGAAGPTGLEGEDAGTAWIGITFHGQTDAYDLRKPELERNAFREACCQFAFQKISDLLV
>NZ_CP012288.1|WP_063510373.1|1236619_1237435_+|DUF1275-domain-containing-protein
MRRHVYPAYQQLYFGAFLAAIAGGLDAYTYLQHGGVFAGLQTGNLILLGVSLSKGQFVKVGYYLIAIIAFGLGTIFIRHMQHFFKQNYLKRAYFVLGYEFVLMVLVAMISQRAPDVITVMLLAITAAAQLQEFRKLQDGPFTSLMMTGNIRTTAENLYTGYVHHDVTAQQKATDTGIVIGSFAAGAFLSGIFVPWLKDAAILVPAVLVLGAVFYLAQHSKSTPNRKDPQSDSNEKAWSETTRASVHPHTSEDDTKTDSEPETRSSRRRRKL
>NZ_CP012288.1|WP_046872091.1|1237922_1238834_-|LysR-family-transcriptional-regulator
MTIDDLKDFVTLYQTRNVSDAAVELMMTQSALSKRIQAMENELATKLISTKNKRHLVITESGEVFFRYAKTILTQYGLLTNELAEYRELKKGTLHIGSVPVMSQYGLMEKTSQFMADYPQINIRLEELEGEELLEMLQTKQLDLGILRNMQSQLLNKSQFQFIDIDQDELKIILPITHPLAKQKRISMNNLRDIEVVSLNPGSGIYEQVGNLYQQAGFTPNIRFTSTHIETLLGIIAKSERVTFLFEKSAEPFMTDQFVSRSFETPIYNKLQLVYPQGELTQAGRRFVGYMEVSGTKRLKHKN
>NZ_CP012288.1|WP_046872092.1|1238981_1240457_+|UbiD-family-decarboxylase
MAKKDVYDLRKVLDELKKEPGQYHETNVEVDPDAELSGVYRYIGAGGTVQRPTQEGPAMMFNNVKGFPHTRVLMGLMASRKRVGKMFHHDYHTLGQFLNDSVENPVDPVMVKEADAPTHEVVHKATDPDFDIRKLVAAPTNTPQDAGPYITVGVVYGSNPDKTMSDVTIHRMVLEDKDKLGIYIMPGGRHIGKFAEEYEKMNKPMPITINIGLDPAVTIGATFEPPTTPLGYNELGVAGAIRQEPVQLVDGLTVDEKAIARSEYTLEGYIMPNERIQEDINTHTGKAMPEFPGYDGDANPALQVIKVTAVTHRKDPIMQSVIGPSEEHVSMAGIPTEASILSLTNRAIPGKVLNVYNPPAGGGKLMTIMQIRKENKADEGIQRQAALLAFSSFKELKTVFLVDEDVDIFDMNDVVWTINTRFQADQDIVVLPGMRNHPLDPSERPEYDPKSIRTRGMSSKLIIDGTVPFDMKDQFERAQFKEVKDWKKYLE
>NZ_CP012288.1|WP_056985954.1|1240479_1241040_+|UbiX-family-flavin-prenyltransferase
MKKIIVGITGASGTVYAIDLLEKLHQLDDVEVHLVMSQWAKKNLELETDYSLQQIKALADKTYNVNDQGATIASGSFLNDGMVIVPASMKTVATIAYGIGDNLIARAADVTIKEQRKLVIVPRETPLSVIHLENLTKLAKIGAQIIPPMPAFYNHPKTIQDLVNHQTMKVLDAFGIPNEVDERWKE
>NZ_CP012288.1|WP_056985953.1|1241362_1242706_+|MFS-transporter
MGILVETSLNVTMNTLSNQFGVSVGTVQWITTAYLLLVTIMMAAMAFIMRRFKFRSIFIFSAAAFIVGSIVCAIADSFWILLIGRMIQAIATGLATPLMFQIINVKIPRQHVGTYNGVASMLTSLSPALGPTYGGILNTLMNWRWIFWVVLPLSVIVLIMGMINIDIPVQHKRGEKLSFDSIGMVWLSLVLIGFVWTFNEAGLAGWTSAAFWISLVISILLLLSYAWYNSKSSKEVLDFSLLKKKSVFLHLINYFVLAFVNIGISWLLPMVAEVNLHQTSMVAGLLVLPGALIGAIISPSTGAIMDKKGAFLPLMIGNICLLASVVLFFFLNDVMTSMILLILFVILRVGVAFSFGNVMGAASQQVVPEKRGDINSLFNMMQQYAGAMGTVILASVISSLELHGGSTFSQVRQGSKIDYVILSVLALVALITVIINKSTRNHMTKNN
>NZ_CP012288.1|WP_046870605.1|1242927_1243389_+|universal-stress-protein
MQVDKLKEPLVFHRVLLTVDADDPNSSTRAFQYATTMAHDYQVELCIVSVLEDDDISIFDVMTPGKVDKKEDVVRQAVEDYTTIAEELGVKHVTGLTVGASDVDDVILDKVIPRFKPDLIVCGSDTEDSKHRVPGAVGLRIAKRAQVSVIVVR
>NZ_CP012288.1|WP_062916642.1|1243432_1244803_+|Nramp-family-divalent-metal-transporter
MAKNSNEEKHHIISSTDGANKSLDEINGSVSVPQNAGVFKTFLAYLGPGVLISVGYMDPGNWITSISGGAQFKYRLLSVVLISSLIAMLLQAMAARLGIVTGRDLAQLTREKTSKFGGIVLFIITELAIMATDVAEIIGSAIALELLFGFPLIVGIIITIFDVLLLMLLMKLGFRKIEAIVATLVAVILFVFLYEVILAQPNMPEVLKGFAPGKDLIQNKSMLYIGLGIVGATVMPHNLYLGSSISQTRNFDRNDHKSIRSAIRYTVTDSNMQLTVAFVVNCLLLILGAALFFGINSDLGRFVDLYNALGDSKIVGAIASPVLSTLFAVALLSSGQSSTITGTLSGQIIMEGFIRLKMPMWAQRLVTRLVSVLPVLAFAIYYHGNEAKIENLLTFSQVFLSIALPFAMIPLILFTSSKKIMGEFANRPWVKVCAWIAAVVLVILNVWLIITTVSAL
>NZ_CP012288.1|WP_062916645.1|1245379_1246789_+|pyruvate-oxidase
MSKTINAGIAMMKVIEDWDVKQVYGIPGGSINSTMEALRVEQDKIDYVQVRHEEVGAFAAAAHAKLTGKIGVCFGSAGPGATHLFNGLYDAQMDHAPVLAIIGQVGTSDMNWDSFQEMNENPMFADVSVYNRTVMTADSLPHVIDEAIRRAYKENGVAVVTIPNDFGTKDIPADFWSSGHSYVKPLLPQPDEEKIKAALKLISEAKHPVIFAGIGVNGATEELVTLSKHLKLPVVMSAISKGMIPDDFEGNMGSAYRVSTKPGNETLEQADLIMMIGADFPFARTKGMFNPDAKFIQVDIDSSKIGKRHNVDVPILSDAKQELVALSDEVAHRRFYDACVANRKNWRAYLQQLADKTTSPLGVGSVFKQINRISTGNDVFAIDVGDVTMNSLRFLNMNEKQKFTTSALFATMGYGMGAAIAGKLTYPDRQVFNLTGDGAFAMVMQDLLTQVKEKLHIINVVFSNVSVKF

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Crispr_ID: NZ_CP012288_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012288_4

1406885-1407264

Orphan

Consensus_repeat	Method
CCAGGTGGCACAANAANNACACCAGGTGG	CRT

5 spacers

The CRISPR arrays of NZ_CP012288_4

>merge|NZ_CP012288|4|1406885-1407264|CRT
TCAGGTGGCACAACAAAGACACCAGGCGGTACAACAACGACAACAACGCCGGGTGGTACAACGACAACAACAACACCAGGTGGCACAACAACGACACCAGGTGGAGAAGTAACAACACCAGGCGGTACAGTAACAACGCCGGGTGGTACAATAACAACGCCAGGTGGCACAACAAAGACACCAGGTGGAGAAGTAACAACACCAGGCGGTACAATAACAACGCCAGGTGGCACAGTAAAGACACCAGGTGGAAAAGTAACAACGCCAGGTGGTTCAACTATTACGCCAGGTGGTACAAAAACAACACCAAATGGTACGGTAACATCGCCAGGTGGCACAACAATAAAGACACCAGGTGGCACAACAATAACTCCAGGTGG

>NZ_CP012288|4|2|1406885-1407264|CRT
TCAGGTGGCACAACAAAGACACCAGGCGG	TACAACAACGACAACAACGCCGGGTGGTACAACGACAACAACAACA
CCAGGTGGCACAACAACGACACCAGGTGG	AGAAGTAACAACACCAGGCGGTACAGTAACAACGCCGGGTGGTACAATAACAACG
CCAGGTGGCACAACAAAGACACCAGGTGG	AGAAGTAACAACACCAGGCGGTACAATAACAACG
CCAGGTGGCACAGTAAAGACACCAGGTGG	AAAAGTAACAACGCCAGGTGGTTCAACTATTACG
CCAGGTGGTACAAAAACAACACCAAATGG	TACGGTAACATCGCCAGGTGGCACAACAATAAAGACA
CCAGGTGGCACAACAATAACTCCAGGTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012288.1\|WP_046871592.1\|1417020_1417383_+\|DUF3899-domain-containing-protein	unknown	unknown	gnl\|CDD\|372441
NZ_CP012288.1\|WP_046871140.1\|1395919_1397455_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP012288.1\|WP_056986065.1\|1411866_1412877_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NZ_CP012288.1\|WP_046871595.1\|1419842_1420283_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|378129
NZ_CP012288.1\|WP_046870767.1\|1397922_1399308_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NZ_CP012288.1\|WP_046871185.1\|1403934_1404552_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP012288.1\|WP_144010372.1\|1401095_1401461_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_062909601.1\|1414127_1415321_-\|CotH-kinase-family-protein	unknown	unknown	gnl\|CDD\|378045
NZ_CP012288.1\|WP_062916816.1\|1395197_1395743_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|377129
NZ_CP012288.1\|WP_062916666.1\|1404977_1406762_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_062904481.1\|1407859_1409416_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|282904
NZ_CP012288.1\|WP_046871594.1\|1418238_1419615_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP012288.1\|WP_046871182.1\|1399574_1401080_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236304
NZ_CP012288.1\|WP_046871184.1\|1401848_1402577_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP012288.1\|WP_046871593.1\|1417435_1418242_-\|sugar-phosphatase	unknown	unknown	gnl\|CDD\|182509
NZ_CP012288.1\|WP_046871141.1\|1394926_1395121_+\|DUF2273-domain-containing-protein	unknown	unknown	gnl\|CDD\|227834
NZ_CP012288.1\|WP_052694479.1\|1402603_1403677_+\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_CP012288.1\|WP_046871591.1\|1416095_1416986_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|377085
NZ_CP012288.1\|WP_056986062.1\|1415363_1415864_-\|SH3-like-domain-containing-protein	unknown	unknown	unknown
NZ_CP012288.1\|WP_056986064.1\|1412879_1413863_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|132997

Protein	Function_ID	Function_description	E-value
NZ_CP012288.1\|WP_046871592.1\|1417020_1417383_+\|DUF3899-domain-containing-protein	gnl\|CDD\|372441	pfam13038, DUF3899, Domain of unknown function (DUF3899). Putative Tryptophanyl-tRNA synthetase.	4.35052e-07
NZ_CP012288.1\|WP_056986065.1\|1411866_1412877_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	3.68527e-17
NZ_CP012288.1\|WP_046871595.1\|1419842_1420283_+\|DUF1934-domain-containing-protein	gnl\|CDD\|378129	pfam09148, DUF1934, Domain of unknown function (DUF1934). Members of this family are found in a set of hypothetical bacterial proteins. Their precise function has not, as yet, been defined.	6.06128e-32
NZ_CP012288.1\|WP_046870767.1\|1397922_1399308_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.7232e-175
NZ_CP012288.1\|WP_046871185.1\|1403934_1404552_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.0588e-53
NZ_CP012288.1\|WP_062909601.1\|1414127_1415321_-\|CotH-kinase-family-protein	gnl\|CDD\|378045	pfam08757, CotH, CotH kinase protein. Members of this family include the spore coat protein H (cotH). This protein is an atypical protein kinase that phosphorylates CotB and CotG.	2.9561e-17
NZ_CP012288.1\|WP_062916816.1\|1395197_1395743_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	4.77443e-34
NZ_CP012288.1\|WP_062904481.1\|1407859_1409416_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|282904	pfam05109, Herpes_BLLF1, Herpes virus major outer envelope glycoprotein (BLLF1). This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.	0.00210212
NZ_CP012288.1\|WP_046871594.1\|1418238_1419615_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	8.66568e-145
NZ_CP012288.1\|WP_046871182.1\|1399574_1401080_+\|hypothetical-protein	gnl\|CDD\|236304	PRK08581, PRK08581, amidase domain-containing protein.	0.000287189
NZ_CP012288.1\|WP_046871184.1\|1401848_1402577_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	6.54021e-51
NZ_CP012288.1\|WP_046871593.1\|1417435_1418242_-\|sugar-phosphatase	gnl\|CDD\|182509	PRK10513, PRK10513, sugar phosphate phosphatase; Provisional.	8.49459e-107
NZ_CP012288.1\|WP_046871141.1\|1394926_1395121_+\|DUF2273-domain-containing-protein	gnl\|CDD\|227834	COG5547, COG5547, Small integral membrane protein [Function unknown].	1.49491e-11
NZ_CP012288.1\|WP_052694479.1\|1402603_1403677_+\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	5.89215e-58
NZ_CP012288.1\|WP_046871591.1\|1416095_1416986_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	9.01093e-50
NZ_CP012288.1\|WP_056986064.1\|1412879_1413863_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	3.7817e-13
NZ_CP012288.1\|WP_046871140.1\|1395919_1397455_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	4.59589e-16

>NZ_CP012288.1|WP_062916666.1|1404977_1406762_+|KxYKxGKxW-signal-peptide-domain-containing-protein
MGKNNILGRAKKIDEHYKMYKDGKRWMFAGMAMLSLGIGMATQVNDAHADTVVPTANVATTSSASKSSAASSTASSSASVSSASNSSVTSNSVNSSSASVGSASKSGATSSATSSSASVSSASNSSVTSSTVSSSTSVSSVSKSGATSSTATSNVTPNVKVPSSVTSISDATSSATVTNLVDPTNADIAAAKSAALIAYETTGKPQMITAAAAASVTAFTSTKTTVDTNPSTETDVSKTNPTKVTEDTGQGEQGTDALQAGSGAPTSTNMNVVVGSTIGVSGTVAGDQKTYLQVEVPDGLKVNTNGNATVYTTISIPADDLSILTGLIEGIGTALSNGAKLVDAIPGVNFNAQGVVDAFDVSTLISKLGTGVFSAPVTQSADGKYMYVDITGDTGISNILTQDITQTITNLTNAVSAIHVTATVLGFTTDVSGTAASDIMSFLTPAINALKASITTGGSFINKIGSATLVGQIQTTVPVTAVTPTVTGATGSYTLEAQYVNDNTLEADIADLGNNTAKAVLTYKNTPVVSVSKVAGDSKSGYQITGTTTGGGAAARGVTVTVTDSAGNVVGTGVSDANGNTQSELMAALGLKVL
>NZ_CP012288.1|WP_046871185.1|1403934_1404552_+|response-regulator-transcription-factor
MIKIMIVDDHPIYRDGLRVAFKDKKDLKIMAEAENGKIALQKLDTVEIDIVLLDIRMPVLDGIATLGRIKSQFPKVKVIILTGYEDVNVFSKAMSLKTDGFILKSATAQIIFQTIHDVMEGKVIVSPKLLRNTTDYRNLRYELTDEDLDVLTRIAKGERTSKIAGDLHFGERTIKSHLTNIYEKLGVNSRVAAVAKVMQLGLIKL
>NZ_CP012288.1|WP_052694479.1|1402603_1403677_+|DUF916-and-DUF3324-domain-containing-protein
MKRKNLFLILITMVLGVLLTIPVSASELSFGVEANLPENQVDKGVTYFDLNLKPGATQTVTVTVTNSSKDQVKIEPEVNTATTNLNGTVEYQKVAKKNLDTSLKYSLADYVKPVEKTVVLNGKQTKKIHLKITMPKEKFNGVMAGGLRLQDKNQEVSKNAKKKKGTTVQNEYAYLIGIVLQQNTKKVLPDMKLASVKPGQVNLRNVINARLRNVKATYLNKLSVNAKVTKQGNSKVLYRQKRTNMQMAPNSVFNYGLQLNGQSLKAGRYVMNITAKSKKQTWHFKKTFTITREKAAKLNAKDVSIKKDYTWIYVSVGVLIILLLIAIAFWLSRRKLKAKEAENEALRQQLNKHEEDD
>NZ_CP012288.1|WP_046871184.1|1401848_1402577_+|WxL-domain-containing-protein
MINKKLLLSVLSIGTLVLGAVAPVTAFAAESRIEQSTATAAFKENTVDPVDPVDPTNPTDPTDPEIPGTGETGPLTIDYVSSFDFGTHNIPTADATYTAADAKKGDGTAIPNYVQVSDRRAGTPKGWSLTVKEEKQFVDTTGSELSGAALSLGTSQKQAASVGYPTSNDTVTSTTTDTALVPGATTSVMKADVGGGAGTWVDVFGEAGASSVKLMVPAAAHPNADSYSTKLTWTLADTPSGD
>NZ_CP012288.1|WP_144010372.1|1401095_1401461_+|hypothetical-protein
MKRGLLLTILTITSMCLINSPIRGDTHVSEVTSEGRVGFTKGTISPSYPPSDLRPADKVPNGPDTTIKPTVPVSAAKKQQFLPQTDEESDGILQVFGSLGFVVVAWYWMKKNQVRRHNQKN
>NZ_CP012288.1|WP_046871182.1|1399574_1401080_+|hypothetical-protein
MKRILKSLLVFVALTSIFGFYSHRNTYAEEADPMFSLTATKSLMKVGDKVEVKATRLRELTADSENFTLVVPTGMQLDENALSQSSQAANFQSHQESDKLILTVTDQTVKNFTIPLIAETAGTFSLSVLSANQLVTSNVVHVTAMAVPVESSSSTTSGTQAESTSSSAISDSSSTASSTSEQPESSSSADVVSESSSSSSSSETVAKSATSSANKKVISGRSMATAAISIDQTPNILQVSDLYYYGGSTGQPISGFFQDPDKEKVTVNFIITKTSGGGATPPNSGQVQTLGVINTSGGNVKDKFSYMIPAKSLAVHNAGSVGSVYKLTIQFTDGGTKPSSIRQANFRLLYVDGELTLTAPDSIGFGTDLDAKATGNPVYMNKTVTGNPLAVKDTRKIPTGAIVNGWSVTATLAKQMTGTNNEGVLANSLHYINAGTDYVLGPAAVPVKALPKSEPGTTNNISATWNSTNGLAFEPTAGQPVGGGAYSGAVTWTLQDTPGNK
>NZ_CP012288.1|WP_046870767.1|1397922_1399308_+|group-II-intron-reverse-transcriptase/maturase
MRKSQKTEQIADHRWMAGLEDQEHIGARSTASGENTRMSGIKFQDLVLARNNLNLAYQRVTKNKGAAGLDGMTVEDLLPYLKEHRKELLEQLANGTYKPAPVKRVEIPKPNGGTRKLGIPTVVDRMVQQAVAQVMSPVFEQAFSESSFGFRPGRSAQQAIKQVVSFYNEGFHRVVDLDLKAYFDTVNHDLLIKFIEQYVNDPWLTKLIRRFLTSGVMNHGLFESSEKGTPQGGPLSPLLANIYLNELDKELTKRGHKFVRYADDCNIYVKSQRAGQRVLESISNFLEGRLKVTVNQKKTQVGSPLRLKFLGFSLGVGHGGAYVRPAKEPKLRIKQALKQITKRNRGVSTDKIFQEIQQKMRGWIQYFSVGKMTTFIQTLDKWLRSRIRQYIWKQWKKTKTKINNLKRLGLSTSDAVKSANTRKGYWRTAHSKTLLYTLTNEKLERLGLMNLTKTLQFIQSA
>NZ_CP012288.1|WP_046871140.1|1395919_1397455_+|helix-turn-helix-domain-containing-protein
MNKADLLEKTQQSLFKIMEILYLSDGSVSKQTLAQKLDLSPATLKRYLDDLQVDVQPLIDEKKITFCIGANTAEFKLIQNFALDDWIFRLYLKDAPKFQILMYIYKHGSMDSYQLQDDLNMSEASLYRVIKQLNKLLKEFELTIHNGHLQGSELQVRFFYYILFQLTNYFPPKKSFAIDKFVDGLQSELHFYFHSEAVHRVDSWLIISQQRLGSQSVMDSEIPKRVRELYQKNELYQQVSKCYKQAFHMRSATKEQFEIEAFCVMLISMSVFNSKTNVARRFYDIYNSQKTQLADLVEKMNHTITSTLKISRHQWPFELMKLVFDICARPFCFTGDLAHMDEIYSEYYMTHFFSQEARLVVKELMQIFKKEPSTPFSQFIKQNENYFQRRLLFVIRDFRYQQIKDIDIGVDTTFDYYISQMVIDQVRQIFKKDIRVNVTYYQPGNAYDLVLTNYHEEPYDDTDYTYWLTNLGTIHDLEMIKKIVEKNFYAETPVHHLMLKQPNKLHNTKKW
>NZ_CP012288.1|WP_062916816.1|1395197_1395743_+|Asp23/Gls24-family-envelope-stress-response-protein
MNSGRPTPPRPNDHKTDSSVKGELTYENKVVQKIIGIALEEIDGLLTVDGGFFSNVKDKLVNNDDVRAGINTEVGKKQVAVDMDIVAEYGTDIEDIFEQMKRVITREVKEMTHLEVIEVNVNVVDVKTREEYEADSETVQDKAMNAADKTGDFASRKTEDAKHAMSKGRHKIDEKTEPRVE
>NZ_CP012288.1|WP_046871141.1|1394926_1395121_+|DUF2273-domain-containing-protein
MQTFIDKYKLPIIGGVIGLILAILLVTIGFFQTLLLVVLVILGAAVGMYVDRTKLLERYLNNKN
>NZ_CP012288.1|WP_062904481.1|1407859_1409416_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKTPGGSVVTSGGTTTTPGGTVKTPGQNTKTPGGTTTTPGGTIITDGGTTITKGGTTITKGGNVTTPGGNKVTPGGTTTTPGGKVTTPGQNTKTPGGTQTTPGGSKVSNGGTITTPGGTQVGPNAGGDNTTKPSQPVKTPGGSVVTPGGTTTTPGGTVKTPGQNTKTPGGTTTTPGGTIITDGGTTITKGGTTITKGGNVTTPGGNKVTPGGTTTTPGGKVTTPGQNTKTPGGTQTTPGGSKVSNGGTITTPGGTQVGPNAGGDNTTKPSQPVKTPGGSVVTPGGTTTTPGGTVKTPGQNTKTPGGTTTTPGGTIITDGGTTITKGGTTITKGGNVTTPGGNKVTPGGTTTTPGGKVTTPGQNTKTPGGTQTTPGGSKVSNGGTITTPGGTQVGPNAGGDNTTKPSQPVKTPGGSVVTPGGTTTTPGGTVKTPGQNTSTPGGTRVNFSGTELQNNTNANLNNTSGSSVNASKNSQNVNEKGKLPQTSDASNNLSELGVLGMLLMSLLSLVGLKRRKRN
>NZ_CP012288.1|WP_056986065.1|1411866_1412877_+|glycosyltransferase-family-2-protein
MQKTVSIIIPFHNEPIYTVFNVLTSINNQIGINFEKVEVILVNDGGPELPNGKDTFRLLKNLDVIYLRSSEGHGPGPARQMGMDHASGQYFMFMDADDQFHIDGALLDFFNVTDKKNYDIIAGKYVEQAKSIENGNLFYVFHDNNENYSIFSKWFNRDLIERYHIRWADDLKVFEDTYFVGLAYEFATNIKQIDAYSYTWLYNSKSVGRRIDNSGISFDDQLHIWSRGRRYFLEQVQKYKAARVEDWFVDYVADIYYRQKKFKPANMEKFTEEHIHLLREFSSYWLPARVKIMQAIISYNIKKTNYTGLSNDDAIKFLYDTEQYALGNQFSEKETK
>NZ_CP012288.1|WP_056986064.1|1412879_1413863_+|glycosyltransferase-family-2-protein
MDAKKEFRPTVSIIIPFYNEDEYQLMIALSSINYQIGIDFREVEIILVGDGGKKLKSLDDFSVLNNLNIRYKYFTNSGGAGVARQRGMEMAKGRYYMFVDADDEFYYDGALQEFFDVVKKGDHEVIVAKYIEQGRNADGSYFYLHNDPVWSAAYAKWFNRDYVERMGLHWLDDVRIFEDVYFCAMAVELASDVVWLDSFVYSWLYNEKSTVRDPALKFNIRLDQWAKMNKYYLRKIKEKAPQKLAFDFGNSIATLFYWEKKNPGYDEKTLDHEQQLMLKENADLWGSTQDIMQQQLQALHQPGSEYENYDISDFSKYLAHSEKLLKS
>NZ_CP012288.1|WP_062909601.1|1414127_1415321_-|CotH-kinase-family-protein
MATLFIGSDTASRSKAKSKISSVTIRQPNGENTLAQIKFSVQGNYTKDFKRRNFEFELYNDFEQSQSKLVKFGTWQPRSKFSLRGDYTDQTHSRNGTGYSLWKEILATEKIYPEKIRDKEMLGTIQTQPVNVFFDGMNYGIYSLSSYFDANSLKLDSNNEDEILLLALDGYTNDKDLAFANPTARLNDSDFGVMSHHTAADKKLFTNTNRLMKFIHSSTDQEFHKNAQNYFDPLNLIDYILFTGALDAFDNVTHNTTVFTYDGKHWLFSLIDLDISFDIDADGKLLSNPHPVLNHIDSPLFKRIFACFPEEVESRWQELRKTILSEDHVIDAYKQKMDEIGGTNFAADQNIWHSPTGPTSSLANVTNFVHRQLPKCDHIIEKSFHSNLLNGFKIDFK
>NZ_CP012288.1|WP_056986062.1|1415363_1415864_-|SH3-like-domain-containing-protein
MSDSNYDVYVNNMVEVNYDATIDQTARFDGLYKGMMWPYNHGDVAGNRDARPLHGTAIHVTQEANLNTGMTFVKFNWQGNDVWIPKEGVIPPTFDSQISLTNQLATLAKTNIDYPYFKDIPQTKKFSHIPIGYINKDRIAGQTILVTARAIRSDNQEFKQFFTNGS
>NZ_CP012288.1|WP_046871591.1|1416095_1416986_+|YihY/virulence-factor-BrkB-family-protein
MLRRFQQTSFFDFITIFLRRYKKGNISNNGIVLAYYTLLSFFPLLLLIGNVLPLLNLPVNTVLKYVNRIMPENIYKILSPLIKQLLTTNNGGVLSIGVVVALWSASKGISAFQQALNATYDMENTTNAILMRILSFLIVLLFMVALIIIVFSFSFGQVALAYLTPLLQIPQDFINFVETIKWPITILGIWLILTILYMIVPMARVRWRYAWAGALFAMIGLVILTQFFTLYLRYFGGAVTTYKTIGTFIIIMLWLDFLAEIMLIGGVINAALQEKISGLPFKPKLSHLKRNHQTSH
>NZ_CP012288.1|WP_046871592.1|1417020_1417383_+|DUF3899-domain-containing-protein
MTITENIKKHKALTSEALIVILMLIDWLIFKDPLKVSNHFFMAGLLLLIVGIFFVLERGHLFTGWFRRPAKGEDDSDRKKIDVHKVGREKNGPIVITKPARYFLNIGSFTIIVSVLISLF
>NZ_CP012288.1|WP_046871593.1|1417435_1418242_-|sugar-phosphatase
MIKLIAIDLDGTLLTDDKHIAAETVTAIKQASQSGVKVVLCSGRPLTGVAEHLHTLGLSGNDQYVITFNGALVQTIEGRVLIHHTLNYNDYTDLEALSRKLHNHFHVETENHIYTANKNISPYTIGESFYVRMAIRYRAVGDMPANFKISKGMFIDPPEKITELRKKIPQTFLDKYYFVQSEPYFLEVLNKSASKGNALKGLTKRLNLLPENVMAIGDQGNDLSMLQFAGTPVAMGNAIPEAKKLATFITSTNEENGVAKAIQKFVLD
>NZ_CP012288.1|WP_046871594.1|1418238_1419615_-|HD-domain-containing-protein
MDYRNQMLPMEKVFRDPVHDYVYVQNQVILDLINTKEFQRLRRIHQLGTTSLVFHGAEHTRFSHSLGCYEVARRICDNFERNYPTKTPGDGLWDNSERLVTLCAALLHDIGHGAYSHTFEHIFHTDHEWYTEQIITSPETEVNKVLRRVSPKFPDEVASVISHKYPNPQVVQMISSQIDADRMDYLLRDSYYTGTNYGTFDLTRILRVMRPYKGGIAFSISGIHAVEDFIVSRFQMYLQVYFHPVSRSMEMILSHLLQRANEIYGGNQKDADKQRNFVPYFLLPFFDHTATVTDYLRLDDGVLNTYFQQWEDDQDPVLNDLSKRFLNRIPLKSVRFTHETEYLLPELRNLIEKAGFNSTYYTAVNDSYDLPYDAYDPSTSKPRTQIELMQHDGTLVELSTASALVAAITGRVSGDQRFFFPKKMLSQDAGELFHPLYQEFQSYIKNGVLMDAKEGHLS
>NZ_CP012288.1|WP_046871595.1|1419842_1420283_+|DUF1934-domain-containing-protein
MDELNTGVPIAIHLDTYITQEGEQSHFTFDEDGQLFQMGDSVYLRYQETDEHTKEPVPVTMKIDNEGDVLLTRSGENKLRLRFSNGKRIQARYRTPYGILPVDTVTPFLEVRMRDQPISGTVNVNYQLFAGESLLGDYKIRLQFTA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP012288_3	3.3\|1234200\|31\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234200-1234230	31	NZ_CP012288.1	976925-976955	0	1.0

1. spacer 3.3|1234200|31|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to position: 976925-976955, mismatch: 0, identity: 1.0

cacttccacatttttggcaccatcaaacgca	CRISPR spacer
cacttccacatttttggcaccatcaaacgca	Protospacer
*******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	NC_019526	Enterobacteria phage vB_KleM-RaK2, complete genome	344166-344195	6	0.8
NZ_CP012288_3	3.2\|1234133\|31\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234133-1234163	31	NC_011990	Agrobacterium radiobacter K84 plasmid pAtK84b, complete sequence	89039-89069	7	0.774
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	MH051916	Enterobacteria phage vB_EcoM_IME340, complete genome	124535-124564	7	0.767
NZ_CP012288_3	3.11\|1234729\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234729-1234758	30	MW117965	Synechococcus phage S-H38, complete genome	72791-72820	7	0.767
NZ_CP012288_3	3.14\|1234927\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234927-1234956	30	NC_015383	Burkholderia gladioli BSR3 plasmid bgla_4p, complete sequence	267931-267960	7	0.767
NZ_CP012288_3	3.15\|1234993\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234993-1235022	30	MN693904	Marine virus AFVG_250M977, complete genome	513-542	7	0.767
NZ_CP012288_3	3.1\|1234067\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234067-1234096	30	NZ_CP016890	Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence	419338-419367	8	0.733
NZ_CP012288_3	3.1\|1234067\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234067-1234096	30	MN693541	Marine virus AFVG_25M436, complete genome	28757-28786	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	Y00122	Bacteriophage T4 genes nrdC, 49 and 55 (5' terminus)	1029-1058	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	KM607002	Enterobacteria phage RB55, complete genome	47527-47556	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	KJ477684	Enterobacteria phage T4 strain wild, complete genome	47549-47578	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	HM137666	Enterobacteria phage T4T, complete genome	47549-47578	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	NC_000866	Enterobacteria phage T4, complete genome	47562-47591	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	KX828711	Shigella phage SH7, complete genome	42355-42384	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	KJ477686	Enterobacteria phage T4 strain GT7, complete genome	47549-47578	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	KJ477685	Enterobacteria phage T4 strain 147, complete genome	45441-45470	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	HE956711	Yersinia phage phiD1 complete genome	44164-44193	8	0.733
NZ_CP012288_3	3.5\|1234333\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234333-1234362	30	KM607003	Enterobacteria phage RB59, complete genome	47527-47556	8	0.733
NZ_CP012288_3	3.19\|1235257\|30\|NZ_CP012288\|CRISPRCasFinder,CRT	1235257-1235286	30	CP046512	Bacillus cereus strain JHU plasmid p1, complete sequence	129098-129127	8	0.733
NZ_CP012288_3	3.3\|1234200\|31\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234200-1234230	31	MT932329	Campylobacter phage F379, complete genome	36544-36574	9	0.71
NZ_CP012288_3	3.3\|1234200\|31\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234200-1234230	31	NC_019507	Campylobacter phage CP21, complete genome	162218-162248	9	0.71
NZ_CP012288_3	3.3\|1234200\|31\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1234200-1234230	31	HE815464	Campylobacter phage CP21 complete sequence	162218-162248	9	0.71
NZ_CP012288_3	3.18\|1235191\|30\|NZ_CP012288\|PILER-CR,CRISPRCasFinder,CRT	1235191-1235220	30	MN694366	Marine virus AFVG_250M1050, complete genome	29824-29853	9	0.7

1. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to NC_019526 (Enterobacteria phage vB_KleM-RaK2, complete genome) position: , mismatch: 6, identity: 0.8

-tattatatgcagatcctaatgttgaactaa	CRISPR spacer
atgcta-atgcagatcctaatgttaaacttc	Protospacer
 *..** *****************.****

2. spacer 3.2|1234133|31|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to NC_011990 (Agrobacterium radiobacter K84 plasmid pAtK84b, complete sequence) position: , mismatch: 7, identity: 0.774

actttccaaaagccaagaaagctggttgaaa	CRISPR spacer
actatgcaaaagccaagaaagctgtcatata	Protospacer
*** * ****************** .  * *

3. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to MH051916 (Enterobacteria phage vB_EcoM_IME340, complete genome) position: , mismatch: 7, identity: 0.767

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactag	Protospacer
 .*  ******* ***** **********.

4. spacer 3.11|1234729|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to MW117965 (Synechococcus phage S-H38, complete genome) position: , mismatch: 7, identity: 0.767

aaaagtttgtgctgccaatggcaggaacgt	CRISPR spacer
gcaagtttatgatgccaatggcaggatgtt	Protospacer
. ******.** **************   *

5. spacer 3.14|1234927|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to NC_015383 (Burkholderia gladioli BSR3 plasmid bgla_4p, complete sequence) position: , mismatch: 7, identity: 0.767

tactcaatcgcaaattgattccgcaccgga	CRISPR spacer
aggcgaatcgcacattgaatccgcaccgga	Protospacer
 . . ******* ***** ***********

6. spacer 3.15|1234993|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to MN693904 (Marine virus AFVG_250M977, complete genome) position: , mismatch: 7, identity: 0.767

atcttatctggcatttcatcacacatacgt	CRISPR spacer
aaatcctcttgcatttaatcacacatacga	Protospacer
*  *. *** ****** ************

7. spacer 3.1|1234067|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016890 (Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

gtgataccagtgccgtttaacgctgacatc	CRISPR spacer
gactatctggtgccggttaacgctgacatc	Protospacer
*     *..****** **************

8. spacer 3.1|1234067|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to MN693541 (Marine virus AFVG_25M436, complete genome) position: , mismatch: 8, identity: 0.733

gtgataccagtgccgtttaacgctgacatc	CRISPR spacer
ccaataccagtgccgtataccgctgagtta	Protospacer
 ..************* ** ******  *

9. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to Y00122 (Bacteriophage T4 genes nrdC, 49 and 55 (5' terminus)) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

10. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to KM607002 (Enterobacteria phage RB55, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

11. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to KJ477684 (Enterobacteria phage T4 strain wild, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

12. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to HM137666 (Enterobacteria phage T4T, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

13. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to NC_000866 (Enterobacteria phage T4, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

14. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to KX828711 (Shigella phage SH7, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

15. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to KJ477686 (Enterobacteria phage T4 strain GT7, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

16. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to KJ477685 (Enterobacteria phage T4 strain 147, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

17. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to HE956711 (Yersinia phage phiD1 complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

18. spacer 3.5|1234333|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to KM607003 (Enterobacteria phage RB59, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

19. spacer 3.19|1235257|30|NZ_CP012288|CRISPRCasFinder,CRT matches to CP046512 (Bacillus cereus strain JHU plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

taatgtaaaaaagcttgactgtatacacat	CRISPR spacer
taatgtaaaaaagctggactatatgagagg	Protospacer
*************** ****.***. . .

20. spacer 3.3|1234200|31|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to MT932329 (Campylobacter phage F379, complete genome) position: , mismatch: 9, identity: 0.71

cacttccacatttttggcaccatcaaacgca	CRISPR spacer
tatgtctacacttttggcaccatcaaatatt	Protospacer
.*. **.***.****************...

21. spacer 3.3|1234200|31|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to NC_019507 (Campylobacter phage CP21, complete genome) position: , mismatch: 9, identity: 0.71

cacttccacatttttggcaccatcaaacgca	CRISPR spacer
tatgtctacacttttggcaccatcaaatatt	Protospacer
.*. **.***.****************...

22. spacer 3.3|1234200|31|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to HE815464 (Campylobacter phage CP21 complete sequence) position: , mismatch: 9, identity: 0.71

cacttccacatttttggcaccatcaaacgca	CRISPR spacer
tatgtctacacttttggcaccatcaaatatt	Protospacer
.*. **.***.****************...

23. spacer 3.18|1235191|30|NZ_CP012288|PILER-CR,CRISPRCasFinder,CRT matches to MN694366 (Marine virus AFVG_250M1050, complete genome) position: , mismatch: 9, identity: 0.7

gtgtggcgttggctaacgttgttgagggca	CRISPR spacer
ctgtggcattggctgacgttgttgctaatt	Protospacer
 ******.******.*********  ...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

55560 : 108417

Mycobacterium_phage(17.65%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904584.1\|55560_56766_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.6e-90	45.3
WP_046871473.1\|57223_58582_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	5.6e-44	33.6
WP_046871474.1\|58675_59404_-	dihydrofolate reductase family protein	NA	NA	NA	NA
WP_056986378.1\|59612_60908_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	6.2e-69	39.3
WP_046871475.1\|61073_62495_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_046871476.1\|62567_63218_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_046871477.1\|63241_63634_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_046871478.1\|63782_64232_-	hypothetical protein	NA	NA	NA	NA
WP_046871495.1\|64232_65078_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.5e-43	37.8
WP_052694504.1\|65810_66608_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_046871479.1\|66871_68560_-	SH3-like domain-containing protein	NA	NA	NA	NA
WP_062916500.1\|69041_76703_-	KxYKxGKxW signal peptide domain-containing protein	NA	NA	NA	NA
WP_046871481.1\|77230_78559_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	4.0e-87	41.3
WP_046871482.1\|78607_79126_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.8e-26	40.7
WP_046871497.1\|79125_81444_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.5e-86	34.2
WP_046871483.1\|81595_81928_-	DUF1049 domain-containing protein	NA	NA	NA	NA
WP_062916502.1\|81940_82756_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	7.7e-09	28.5
WP_046871485.1\|82771_83698_-	ribonuclease Z	NA	NA	NA	NA
WP_046871486.1\|83878_84154_+	hypothetical protein	NA	NA	NA	NA
WP_046871487.1\|84169_84952_+	hypothetical protein	NA	NA	NA	NA
WP_081213081.1\|85015_87010_-	acetyltransferase	A0A1R3Y5Q6	Salmonella_virus	4.5e-26	28.6
WP_046872210.1\|87030_88326_-	GTPase ObgE	NA	NA	NA	NA
WP_056986325.1\|88458_90249_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_181407262.1\|90414_91146_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.3e-27	37.5
WP_046872207.1\|91147_92626_-	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_167630938.1\|92923_93073_+	hypothetical protein	NA	NA	NA	NA
WP_046872206.1\|93106_93397_-	nucleoside triphosphate pyrophosphohydrolase family protein	A0A1S7FYY8	Listeria_phage	1.1e-18	47.3
WP_046872205.1\|93400_93991_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_046872204.1\|94093_95341_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.1e-136	59.3
WP_003555349.1\|95486_96224_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_003555353.1\|96233_97457_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_057808145.1\|97709_98957_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046872203.1\|99069_100407_-	trigger factor	NA	NA	NA	NA
WP_046872202.1\|100613_101801_-	elongation factor Tu	A0A076FFS6	Aureococcus_anophage	1.6e-31	27.9
WP_145974412.1\|101990_102905_-	hypothetical protein	NA	NA	NA	NA
WP_062904280.1\|103062_104310_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_056986483.1\|104459_106169_-	ribonuclease J	NA	NA	NA	NA
WP_046872199.1\|106586_106856_-	30S ribosomal protein S15	NA	NA	NA	NA
WP_046872291.1\|107049_108417_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

243684 : 284444

Mycobacterium_phage(16.67%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904581.1\|243684_244932_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046871325.1\|245014_245407_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_056986228.1\|245421_245865_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_046871323.1\|245986_246754_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_081036080.1\|246764_247562_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_046871321.1\|247554_248427_-	energy-coupling factor ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.4e-08	28.7
WP_056986230.1\|248402_249239_-	energy-coupling factor ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-19	31.2
WP_046871319.1\|249472_249856_-	50S ribosomal protein L17	NA	NA	NA	NA
WP_056986231.1\|249877_250822_-	DNA-directed RNA polymerase subunit alpha	NA	NA	NA	NA
WP_046871317.1\|250904_251294_-	30S ribosomal protein S11	NA	NA	NA	NA
WP_046871316.1\|251315_251681_-	30S ribosomal protein S13	NA	NA	NA	NA
WP_011668476.1\|251701_251821_-	50S ribosomal protein L36	NA	NA	NA	NA
WP_046871315.1\|251848_252067_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_046871314.1\|252229_252889_-	adenylate kinase	NA	NA	NA	NA
WP_046871313.1\|252909_254223_-	preprotein translocase subunit SecY	NA	NA	NA	NA
WP_056986232.1\|254222_254657_-	50S ribosomal protein L15	NA	NA	NA	NA
WP_046871311.1\|254685_254868_-	50S ribosomal protein L30	NA	NA	NA	NA
WP_046871310.1\|254880_255384_-	30S ribosomal protein S5	NA	NA	NA	NA
WP_080945511.1\|255405_255762_-	50S ribosomal protein L18	NA	NA	NA	NA
WP_046871308.1\|255807_256344_-	50S ribosomal protein L6	NA	NA	NA	NA
WP_046871307.1\|256374_256773_-	30S ribosomal protein S8	NA	NA	NA	NA
WP_074693903.1\|256806_256992_-	type Z 30S ribosomal protein S14	NA	NA	NA	NA
WP_046871306.1\|257010_257553_-	50S ribosomal protein L5	NA	NA	NA	NA
WP_046871305.1\|257578_257890_-	50S ribosomal protein L24	NA	NA	NA	NA
WP_046871304.1\|257923_258292_-	50S ribosomal protein L14	NA	NA	NA	NA
WP_046871303.1\|258346_258613_-	30S ribosomal protein S17	NA	NA	NA	NA
WP_046871302.1\|258640_258835_-	50S ribosomal protein L29	NA	NA	NA	NA
WP_046871301.1\|258824_259259_-	50S ribosomal protein L16	NA	NA	NA	NA
WP_046871300.1\|259261_259933_-	30S ribosomal protein S3	NA	NA	NA	NA
WP_046871299.1\|259945_260293_-	50S ribosomal protein L22	NA	NA	NA	NA
WP_046871298.1\|260305_260596_-	30S ribosomal protein S19	NA	NA	NA	NA
WP_046871297.1\|260623_261472_-	50S ribosomal protein L2	NA	NA	NA	NA
WP_062916523.1\|261498_261786_-	50S ribosomal protein L23	NA	NA	NA	NA
WP_046871295.1\|261785_262409_-	50S ribosomal protein L4	NA	NA	NA	NA
WP_046871294.1\|262427_263063_-	50S ribosomal protein L3	NA	NA	NA	NA
WP_046871293.1\|263110_263419_-	30S ribosomal protein S10	NA	NA	NA	NA
WP_046871292.1\|263732_264287_+	cysteine hydrolase	G3MA16	Bacillus_virus	1.1e-30	41.7
WP_062916525.1\|264449_265328_+\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	6.6e-06	26.7
WP_003555353.1\|265407_266631_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_003555349.1\|266640_267378_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_062916527.1\|267493_267832_+\|transposase	transposase	NA	NA	NA	NA
WP_062904580.1\|267951_270051_-	elongation factor G	E4ZFJ7	Streptococcus_phage	1.5e-64	27.9
WP_046871290.1\|270183_270654_-	30S ribosomal protein S7	NA	NA	NA	NA
WP_046871289.1\|270667_271081_-	30S ribosomal protein S12	NA	NA	NA	NA
WP_052694487.1\|271428_272112_+	prepilin peptidase	NA	NA	NA	NA
WP_062916529.1\|272187_275832_-	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	3.1e-65	24.7
WP_062904579.1\|276033_279654_-	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	8.4e-55	25.8
WP_056986283.1\|279909_282396_-\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	1.5e-127	40.1
WP_056986284.1\|282416_282881_-	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_062904581.1\|283196_284444_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7

DBSCAN-SWA_3

371044 : 424379

Lactococcus_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904288.1\|371044_372250_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.6e-90	45.3
WP_046872242.1\|372539_373217_-	Fic family protein	NA	NA	NA	NA
WP_010620873.1\|373483_374656_+\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_046872241.1\|374794_375829_-	DUF4767 domain-containing protein	NA	NA	NA	NA
WP_062904581.1\|376160_377408_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_056986278.1\|377559_379113_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.6e-18	29.6
WP_046872239.1\|379252_380179_-	type I pantothenate kinase	NA	NA	NA	NA
WP_056986279.1\|380198_382493_-	AAA family ATPase	NA	NA	NA	NA
WP_062916543.1\|383234_385091_+	monovalent cation:proton antiporter family protein	NA	NA	NA	NA
WP_046872355.1\|385254_385920_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_062904099.1\|385937_387572_+	amino acid permease	NA	NA	NA	NA
WP_046872353.1\|387646_388000_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_046872352.1\|388096_388666_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_100077841.1\|388861_389020_-	hypothetical protein	NA	NA	NA	NA
WP_046872360.1\|389109_389517_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046872351.1\|389690_390731_-	zinc-dependent alcohol dehydrogenase family protein	A0A0G2Y405	Acanthamoeba_polyphaga_mimivirus	1.9e-07	29.4
WP_056986217.1\|390899_391874_-	amidohydrolase	NA	NA	NA	NA
WP_052694561.1\|391885_392338_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_052694560.1\|392461_393274_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_046872349.1\|393445_394324_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_052694559.1\|394541_395123_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_155387004.1\|395452_395614_+	hypothetical protein	NA	NA	NA	NA
WP_046872347.1\|395803_396481_-	DUF4867 family protein	NA	NA	NA	NA
WP_046872346.1\|396546_397542_-	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_046872345.1\|397706_398225_-	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_046872344.1\|398544_398973_-	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
WP_046872343.1\|399349_399841_+	PTS N-acetylgalactosamine transporter subunit IIB	NA	NA	NA	NA
WP_046872342.1\|399898_400708_+	PTS N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_046872341.1\|400697_401528_+	PTS N-acetylgalactosamine transporter subunit IID	NA	NA	NA	NA
WP_046872340.1\|401554_401998_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_046870886.1\|404139_404649_-	hypothetical protein	NA	NA	NA	NA
WP_046870885.1\|404667_405420_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_056986108.1\|405706_406741_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_056986109.1\|406882_408151_+	MFS transporter	NA	NA	NA	NA
WP_046870882.1\|408167_409748_+	family 78 glycoside hydrolase catalytic domain	NA	NA	NA	NA
WP_056986110.1\|409749_411012_+	MFS transporter	NA	NA	NA	NA
WP_056986111.1\|411143_411494_-	hypothetical protein	NA	NA	NA	NA
WP_056986112.1\|411673_412717_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_046870879.1\|412732_413905_-	SIS domain-containing protein	NA	NA	NA	NA
WP_046870878.1\|413945_414689_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_056986113.1\|414833_415670_-	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_046870876.1\|415653_416562_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_046870875.1\|416576_417071_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_046870874.1\|417219_419268_-	hypothetical protein	NA	NA	NA	NA
WP_046870873.1\|419282_419678_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_052694462.1\|419915_420836_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_062916545.1\|420998_422057_+\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	6.1e-06	26.7
WP_003555353.1\|422136_423360_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_003555349.1\|423369_424107_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_145974414.1\|424160_424379_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_4

432988 : 478139

Streptococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904288.1\|432988_434194_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.6e-90	45.3
WP_062916548.1\|434814_436449_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046870864.1\|436785_438063_+	GTPase HflX	NA	NA	NA	NA
WP_046871452.1\|438147_439773_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046871451.1\|440101_441436_+	amino acid permease	NA	NA	NA	NA
WP_155515903.1\|441453_441606_+	hypothetical protein	NA	NA	NA	NA
WP_081036069.1\|441606_442356_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_046872291.1\|443020_444388_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_056986423.1\|444503_445631_-	hypothetical protein	NA	NA	NA	NA
WP_155515913.1\|445681_445840_-	hypothetical protein	NA	NA	NA	NA
WP_046871448.1\|445944_446841_-	ABC transporter permease	NA	NA	NA	NA
WP_046871447.1\|446853_447813_-	ABC transporter permease	NA	NA	NA	NA
WP_046871446.1\|447817_448765_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.0e-17	30.8
WP_046871445.1\|448765_449764_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-18	30.0
WP_035181568.1\|450021_451293_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_046871444.1\|451471_452125_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_046871443.1\|452138_452777_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_046871442.1\|452773_453610_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_181407275.1\|453622_454357_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	6.7e-36	38.2
WP_062904581.1\|454632_455880_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046871440.1\|456135_456993_-	DUF2975 domain-containing protein	NA	NA	NA	NA
WP_046871439.1\|457012_457495_-	hypothetical protein	NA	NA	NA	NA
WP_056986609.1\|457657_458095_-	transcriptional repressor	NA	NA	NA	NA
WP_172793931.1\|458170_458743_-	guanylate kinase	NA	NA	NA	NA
WP_046871436.1\|458997_459177_+	hypothetical protein	NA	NA	NA	NA
WP_046870767.1\|459268_460654_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	6.7e-29	27.2
WP_046872505.1\|461057_461621_-	ECF transporter S component	NA	NA	NA	NA
WP_062916551.1\|461625_462459_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_062904563.1\|464746_467185_+	Xaa-Pro dipeptidyl-peptidase	NA	NA	NA	NA
WP_056986466.1\|467205_468048_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_062904288.1\|469057_470263_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.6e-90	45.3
WP_046872562.1\|470807_471362_+	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_046872561.1\|471415_472324_+	proline-specific peptidase family protein	NA	NA	NA	NA
WP_046872560.1\|472388_473936_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2H4UUX5	Bodo_saltans_virus	1.2e-42	28.4
WP_046872559.1\|474077_474455_+	VOC family protein	NA	NA	NA	NA
WP_062916553.1\|475758_476589_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.9e-42	40.6
WP_035181568.1\|476867_478139_+\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

503137 : 563898

Mycobacterium_phage(33.33%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904581.1\|503137_504385_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046870754.1\|504614_505073_+	universal stress protein	NA	NA	NA	NA
WP_046870755.1\|505144_506029_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_056986150.1\|506060_506807_+	NADPH-dependent oxidoreductase	NA	NA	NA	NA
WP_062904424.1\|506974_508222_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	4.1e-09	24.7
WP_056986599.1\|508370_510737_-	phosphoketolase family protein	NA	NA	NA	NA
WP_046872328.1\|510976_511699_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_046872291.1\|511887_513255_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_080945589.1\|513379_513883_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_046872418.1\|514012_515542_-	accessory Sec system glycosyltransferase Asp1	NA	NA	NA	NA
WP_062916555.1\|515542_517102_-	glycosyltransferase	NA	NA	NA	NA
WP_081115620.1\|517320_518568_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_052694568.1\|518706_520107_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_046872420.1\|520596_521133_-	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_046872421.1\|521284_521620_+	hypothetical protein	NA	NA	NA	NA
WP_046872422.1\|521629_522196_+	DUF5067 domain-containing protein	NA	NA	NA	NA
WP_100077862.1\|522366_523344_-	aldo/keto reductase	NA	NA	NA	NA
WP_046872291.1\|523454_524822_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_046872425.1\|525255_526329_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	3.7e-43	35.8
WP_052694569.1\|526426_526957_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046872426.1\|527017_527446_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_056986457.1\|527689_528073_-	hypothetical protein	NA	NA	NA	NA
WP_046872428.1\|528152_530885_-	HAD-IC family P-type ATPase	M1HX51	Paramecium_bursaria_Chlorella_virus	2.0e-69	29.1
WP_046872429.1\|531132_532518_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_062904557.1\|532692_533703_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	4.3e-09	24.7
WP_003555353.1\|533830_535054_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_003555349.1\|535063_535801_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_062904556.1\|535835_536075_-	hypothetical protein	NA	NA	NA	NA
WP_172793946.1\|536390_537182_-	HAD family phosphatase	NA	NA	NA	NA
WP_056986515.1\|537368_537848_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_046872432.1\|537910_538771_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.8e-57	42.1
WP_046872433.1\|539107_539764_+	membrane protein	NA	NA	NA	NA
WP_046872434.1\|539849_540641_+	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_046872435.1\|540671_541616_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_046872436.1\|541709_542120_-	transcriptional regulator Spx	G3MAU4	Bacillus_virus	3.6e-07	31.0
WP_046872437.1\|542594_542852_+	hypothetical protein	NA	NA	NA	NA
WP_046870641.1\|542885_543677_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_046870642.1\|543688_544459_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_046870643.1\|544669_545131_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_052694445.1\|545223_545583_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	5.4e-07	32.3
WP_062916813.1\|545725_546973_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.3
WP_046870645.1\|547158_548391_+	MFS transporter	NA	NA	NA	NA
WP_081213087.1\|549117_549807_-	hypothetical protein	A0A1B3B081	Gordonia_phage	2.5e-08	42.9
WP_046872291.1\|549810_551178_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_046870647.1\|552215_553505_+	adenylosuccinate synthase	L7Y4J5	Megavirus	4.0e-68	35.1
WP_056986257.1\|553530_554499_+	GMP reductase	G3MBI2	Bacillus_virus	5.6e-131	71.6
WP_046870648.1\|554893_555337_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_056986258.1\|555440_556331_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_056986259.1\|556383_557796_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_046870691.1\|557983_558436_+	transcriptional repressor	NA	NA	NA	NA
WP_046870692.1\|558510_559419_-	dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_056986261.1\|560100_561078_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_056986260.1\|561121_562321_-	acetate kinase	NA	NA	NA	NA
WP_046872291.1\|562530_563898_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

700724 : 766207

Streptococcus_phage(25.0%)

integrase,transposase,tRNA

attL 743817:743834|attR 745621:745638

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046871942.1\|700724_702755_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	2.6e-90	36.7
WP_046871941.1\|703088_703937_-	DUF72 domain-containing protein	NA	NA	NA	NA
WP_046871940.1\|704419_705385_-	AEC family transporter	NA	NA	NA	NA
WP_056986090.1\|705454_706837_-	class II fumarate hydratase	NA	NA	NA	NA
WP_046871938.1\|706920_708549_-	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_046871936.1\|709017_709422_+	HicB family protein	A0A1L2JY34	Aeribacillus_phage	1.7e-09	29.6
WP_056986088.1\|709466_710345_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_046872471.1\|711210_711534_-	hypothetical protein	NA	NA	NA	NA
WP_046872470.1\|711642_712599_-	hypothetical protein	NA	NA	NA	NA
WP_046872469.1\|712591_713857_-	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
WP_056986528.1\|713924_714848_-	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_046872466.1\|715479_716499_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_046872291.1\|717466_718834_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_035181568.1\|719035_720307_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_046872291.1\|721427_722795_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_062916587.1\|723366_725979_-	alpha-mannosidase	NA	NA	NA	NA
WP_046871624.1\|725982_727026_-	PTS fructose transporter subunit IIC	NA	NA	NA	NA
WP_046871625.1\|727046_727361_-	PTS fructose transporter subunit IIB	NA	NA	NA	NA
WP_046871626.1\|727373_727832_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_056986100.1\|727824_729753_-	transcription antiterminator	NA	NA	NA	NA
WP_046871627.1\|730015_732322_+	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_046871628.1\|732375_732690_-	hypothetical protein	NA	NA	NA	NA
WP_141306320.1\|732796_733921_-	hypothetical protein	NA	NA	NA	NA
WP_046871630.1\|734239_735685_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_046871631.1\|735721_737020_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_046871633.1\|738575_739676_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_046871634.1\|739844_741155_-	serine/threonine transporter SstT	NA	NA	NA	NA
WP_046871635.1\|741612_742401_+	competence protein ComK	NA	NA	NA	NA
WP_046871636.1\|742434_742671_+	hypothetical protein	NA	NA	NA	NA
WP_046871637.1\|742718_743624_-	restriction endonuclease	NA	NA	NA	NA
743817:743834	attL	NA	NA	NA	NA
WP_046872541.1\|743880_744798_-\|integrase	site-specific integrase	A8ATM2	Listeria_phage	4.0e-78	46.9
WP_056986101.1\|744945_746133_-	restriction endonuclease subunit S	NA	NA	NA	NA
745621:745638	attR	NA	NA	NA	NA
WP_056986102.1\|746129_747719_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.2e-127	50.2
WP_056986105.1\|751480_752251_+	acetoin reductase	W8CYX9	Bacillus_phage	5.2e-07	44.2
WP_046872182.1\|752414_753254_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_046872183.1\|753274_753868_-	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	NA	NA	NA	NA
WP_056986106.1\|754178_754898_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_046872186.1\|755499_756033_-	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_056986107.1\|756138_756828_-	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
WP_046872188.1\|756984_757854_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_046872189.1\|757955_759545_-	hypothetical protein	NA	NA	NA	NA
WP_056986623.1\|759729_761106_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_100078054.1\|761422_761545_+	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_046871693.1\|761801_762002_+	type II toxin-antitoxin system HicA family toxin	A0A1X9I5W4	Streptococcus_phage	2.5e-17	67.8
WP_046871692.1\|762023_762458_+	type II toxin-antitoxin system HicB family antitoxin	A0A1X9I727	Streptococcus_phage	1.4e-44	60.4
WP_046871691.1\|762514_763204_-	hypothetical protein	NA	NA	NA	NA
WP_052694520.1\|763218_764598_-	hypothetical protein	A0A2P0ZKX1	Lactobacillus_phage	1.3e-35	41.0
WP_046872291.1\|764839_766207_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

1000850 : 1054445

Streptococcus_phage(26.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_035181568.1\|1000850_1002122_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_046871416.1\|1002223_1002955_-	methyltransferase domain-containing protein	A0A1X9I6N4	Streptococcus_phage	3.7e-87	60.9
WP_046871417.1\|1002970_1003849_-	proline iminopeptidase-family hydrolase	NA	NA	NA	NA
WP_046871418.1\|1004022_1004355_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_046871419.1\|1004369_1004693_-	plasmid maintenance system killer protein	NA	NA	NA	NA
WP_046871420.1\|1004886_1005342_-	DNA topology modulation protein FlaR	A0A097BYE2	Leuconostoc_phage	1.3e-10	35.0
WP_056986040.1\|1005528_1007094_-	hypothetical protein	NA	NA	NA	NA
WP_062916619.1\|1007249_1009223_-	TetM/TetW/TetO/TetS family tetracycline resistance ribosomal protection protein	E4ZFJ7	Streptococcus_phage	2.0e-66	30.3
WP_046871423.1\|1010441_1012085_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046871424.1\|1012291_1012741_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_100212790.1\|1012864_1014304_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_100212870.1\|1014543_1015386_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_046871426.1\|1015424_1015715_-	hypothetical protein	NA	NA	NA	NA
WP_056986621.1\|1016065_1017295_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7
WP_062904519.1\|1017404_1017692_-	DUF2089 family protein	NA	NA	NA	NA
WP_046871428.1\|1018077_1018422_-	hypothetical protein	NA	NA	NA	NA
WP_046871429.1\|1018801_1020790_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_046871430.1\|1021011_1021851_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_056986505.1\|1022001_1023618_-	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_003555349.1\|1023671_1024409_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_003555353.1\|1024418_1025642_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_010620873.1\|1025911_1027084_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_145974415.1\|1027168_1027381_-	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_056986209.1\|1027377_1029495_-	AAA family ATPase	NA	NA	NA	NA
WP_046872136.1\|1029581_1030061_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_056986211.1\|1030732_1031989_-	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	4.8e-18	27.7
WP_046872134.1\|1032100_1032904_-	MBL fold metallo-hydrolase	A0A2I7SDH3	Paenibacillus_phage	8.1e-35	33.7
WP_062904518.1\|1032991_1034071_-	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_046872133.1\|1034085_1035408_-	hypothetical protein	NA	NA	NA	NA
WP_056986208.1\|1035404_1037252_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	6.8e-37	33.5
WP_046872131.1\|1037270_1037972_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.1e-42	41.5
WP_046872038.1\|1038592_1039222_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_046872037.1\|1039716_1040085_+	DUF1304 family protein	NA	NA	NA	NA
WP_046872036.1\|1040160_1040706_-	C40 family peptidase	A0A217EQL1	Bacillus_phage	4.8e-07	30.7
WP_056986206.1\|1040990_1042187_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	1.8e-54	33.7
WP_056986205.1\|1042301_1043699_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	4.6e-126	53.1
WP_046872033.1\|1043799_1044252_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_046872032.1\|1044257_1046282_-	DHH family phosphoesterase	NA	NA	NA	NA
WP_172793940.1\|1046745_1047891_+	MFS transporter	NA	NA	NA	NA
WP_062904517.1\|1047958_1049320_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_046872031.1\|1049349_1050030_-	EAL domain-containing protein	NA	NA	NA	NA
WP_081213094.1\|1050377_1051625_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	1.2e-08	24.7
WP_046872030.1\|1051746_1051989_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_046872029.1\|1052013_1052565_-	single-stranded DNA-binding protein	U5U726	Lactobacillus_phage	8.3e-39	58.5
WP_046872028.1\|1052603_1052894_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_035181568.1\|1053173_1054445_+\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

1183607 : 1250229

Streptococcus_phage(18.18%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904506.1\|1183607_1184837_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	2.6e-80	48.4
WP_056986165.1\|1185187_1186822_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046871890.1\|1186875_1188294_-	C69 family dipeptidase	NA	NA	NA	NA
WP_046871888.1\|1188747_1188945_+	hypothetical protein	NA	NA	NA	NA
WP_141306204.1\|1189039_1189336_+	hypothetical protein	NA	NA	NA	NA
WP_046871892.1\|1189578_1190235_+	hypothetical protein	NA	NA	NA	NA
WP_046871886.1\|1190658_1191264_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_056986167.1\|1191389_1194137_+	YhgE/Pip domain-containing protein	NA	NA	NA	NA
WP_056986168.1\|1194322_1195936_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046871660.1\|1195955_1197122_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_056986169.1\|1197317_1198616_+	excinuclease ABC subunit A	Q6DMX4	Streptococcus_phage	5.4e-73	37.3
WP_052694514.1\|1198608_1198926_+	hypothetical protein	NA	NA	NA	NA
WP_046871663.1\|1198930_1199347_+	YolD-like family protein	E3W8I0	Leuconostoc_phage	8.8e-09	29.3
WP_046871664.1\|1199527_1200970_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	3.2e-82	36.3
WP_046871665.1\|1201011_1201479_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_080945535.1\|1201620_1202505_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_062916640.1\|1202573_1203785_+	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	3.2e-35	30.1
WP_046871667.1\|1203866_1204409_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_046871668.1\|1204470_1205406_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	1.2e-74	48.4
WP_046871669.1\|1205532_1206183_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.6e-19	33.8
WP_056986171.1\|1206179_1206953_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_046871671.1\|1207076_1208519_+	amino acid permease	NA	NA	NA	NA
WP_062904593.1\|1208648_1210088_+	C69 family dipeptidase	NA	NA	NA	NA
WP_062904581.1\|1210191_1211439_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046872450.1\|1211510_1212917_-	C69 family dipeptidase	NA	NA	NA	NA
WP_046872452.1\|1213011_1214397_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_081036081.1\|1214832_1214991_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_046871865.1\|1215261_1215528_-	hypothetical protein	NA	NA	NA	NA
WP_052694534.1\|1215555_1216353_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_056986237.1\|1216522_1217899_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_046871862.1\|1218157_1219654_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_046871861.1\|1219795_1220713_+	ribokinase	NA	NA	NA	NA
WP_052694533.1\|1220816_1221278_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_155386982.1\|1221347_1221524_-	hypothetical protein	NA	NA	NA	NA
WP_046871860.1\|1221646_1222495_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.4e-45	36.3
WP_056986236.1\|1222551_1223055_-	transcription elongation factor GreA	NA	NA	NA	NA
WP_046871859.1\|1223407_1224409_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_046871858.1\|1224526_1225009_+	winged helix DNA-binding protein	NA	NA	NA	NA
WP_046871857.1\|1225066_1225312_-	hypothetical protein	NA	NA	NA	NA
WP_046871856.1\|1225527_1226040_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_062904505.1\|1226234_1230371_+	type II CRISPR RNA-guided endonuclease Cas9	NA	NA	NA	NA
WP_046872291.1\|1230646_1232014_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_046871854.1\|1232145_1233048_+	type II CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_062904504.1\|1233025_1233283_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_056985955.1\|1233546_1233933_+	type II-A CRISPR-associated protein Csn2	NA	NA	NA	NA
WP_046872502.1\|1235451_1235913_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046872501.1\|1236005_1236479_+	CinA family protein	B5TK85	Pseudomonas_phage	2.1e-14	46.1
WP_063510373.1\|1236619_1237435_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_046872091.1\|1237922_1238834_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_046872092.1\|1238981_1240457_+	UbiD family decarboxylase	NA	NA	NA	NA
WP_056985954.1\|1240479_1241040_+	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_056985953.1\|1241362_1242706_+	MFS transporter	NA	NA	NA	NA
WP_046870605.1\|1242927_1243389_+	universal stress protein	NA	NA	NA	NA
WP_062916642.1\|1243432_1244803_+	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_062916645.1\|1245379_1246789_+	pyruvate oxidase	NA	NA	NA	NA
WP_056986623.1\|1246882_1248259_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_081115592.1\|1248522_1248855_+	hypothetical protein	NA	NA	NA	NA
WP_062904581.1\|1248981_1250229_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7

DBSCAN-SWA_9

1312660 : 1369684

Lactococcus_phage(30.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003555353.1\|1312660_1313884_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_003555349.1\|1313893_1314631_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_046870624.1\|1315290_1316034_-	DUF4811 domain-containing protein	NA	NA	NA	NA
WP_056986376.1\|1316033_1317512_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_046870622.1\|1317678_1318152_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_046870626.1\|1318246_1319371_+	hypothetical protein	NA	NA	NA	NA
WP_062916656.1\|1319664_1321416_+	hypothetical protein	NA	NA	NA	NA
WP_062916659.1\|1321614_1323084_-	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_062916661.1\|1323090_1324464_-	hypothetical protein	NA	NA	NA	NA
WP_062904488.1\|1324870_1326334_+	hypothetical protein	NA	NA	NA	NA
WP_046872079.1\|1326726_1327320_+	ECF transporter S component	NA	NA	NA	NA
WP_046872078.1\|1327382_1328456_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_081036107.1\|1328706_1329180_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046872289.1\|1329816_1330179_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_046872288.1\|1330318_1330921_-	nitroreductase family protein	NA	NA	NA	NA
WP_062904288.1\|1331207_1332413_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.6e-90	45.3
WP_056986615.1\|1332747_1334457_+	SH3-like domain-containing protein	NA	NA	NA	NA
WP_056986616.1\|1334604_1334925_+	hypothetical protein	NA	NA	NA	NA
WP_062904581.1\|1334997_1336245_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046872286.1\|1336529_1337363_+	YitT family protein	NA	NA	NA	NA
WP_046872285.1\|1337432_1338047_+	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	2.1e-06	28.3
WP_046872284.1\|1338181_1338694_+	hypothetical protein	NA	NA	NA	NA
WP_046872283.1\|1339077_1340934_-	FAD/NAD(P)-binding protein	NA	NA	NA	NA
WP_046872282.1\|1342989_1344645_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046872281.1\|1344818_1345535_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_062904581.1\|1345726_1346974_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_056986226.1\|1347292_1350505_+	YhgE/Pip family protein	NA	NA	NA	NA
WP_046870627.1\|1351021_1351648_+	HAD family hydrolase	NA	NA	NA	NA
WP_046870628.1\|1351681_1351915_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_052694444.1\|1352154_1352697_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_046870630.1\|1353064_1354306_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_046870631.1\|1354336_1354525_+	hypothetical protein	NA	NA	NA	NA
WP_056986225.1\|1354542_1355727_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046870633.1\|1356110_1356749_+	LysM peptidoglycan-binding domain-containing protein	A0A288TY55	Enterococcus_phage	1.8e-21	51.9
WP_046870635.1\|1357859_1359317_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	3.9e-35	26.8
WP_056986223.1\|1359628_1361002_+	MATE family efflux transporter	NA	NA	NA	NA
WP_056986222.1\|1361020_1361209_+	hypothetical protein	NA	NA	NA	NA
WP_056986221.1\|1361309_1362512_-	acetate kinase	NA	NA	NA	NA
WP_062904591.1\|1362737_1363697_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_062904581.1\|1363767_1365015_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046870639.1\|1365246_1366908_+	alpha-glucosidase	NA	NA	NA	NA
WP_046870640.1\|1366933_1368217_+	alpha-amylase	NA	NA	NA	NA
WP_056986621.1\|1368454_1369684_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7

DBSCAN-SWA_10

1429262 : 1480203

Streptococcus_phage(23.08%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046871604.1\|1429262_1430162_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_046871605.1\|1430233_1431016_+	hypothetical protein	NA	NA	NA	NA
WP_046871606.1\|1431188_1432565_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_046871607.1\|1432742_1434305_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.3e-68	37.7
WP_046871608.1\|1434597_1434957_+	holo-ACP synthase	NA	NA	NA	NA
WP_046871609.1\|1434963_1436091_+	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	1.8e-35	31.5
WP_141306217.1\|1436168_1436441_+	hypothetical protein	NA	NA	NA	NA
WP_046871611.1\|1436459_1436831_+	type II toxin-antitoxin system PemK/MazF family toxin	A0A291I9M9	Lactobacillus_phage	1.7e-11	37.9
WP_046871612.1\|1436915_1437281_+	DUF488 family protein	NA	NA	NA	NA
WP_046871613.1\|1437277_1437766_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046871614.1\|1437860_1438370_+	QueT transporter family protein	E7DN70	Pneumococcus_phage	2.2e-09	32.7
WP_062904477.1\|1438747_1439395_-	CBS domain-containing protein	NA	NA	NA	NA
WP_046871616.1\|1439527_1440919_-	peptidoglycan binding domain-containing protein	NA	NA	NA	NA
WP_046871617.1\|1441102_1442065_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_046871618.1\|1442392_1442950_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_046871619.1\|1442971_1446478_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_080945531.1\|1446524_1448090_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_062904288.1\|1448640_1449846_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.6e-90	45.3
WP_046871932.1\|1450328_1450598_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_080945556.1\|1450909_1451182_+	septum formation initiator family protein	NA	NA	NA	NA
WP_046871931.1\|1451338_1451830_+	RNA-binding protein S1	NA	NA	NA	NA
WP_062916668.1\|1451912_1453310_+\|tRNA	tRNA lysidine(34) synthetase TilS	A0A0N7G7K4	Chrysochromulina_ericina_virus	1.1e-10	28.7
WP_046871930.1\|1453309_1453852_+	hypoxanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_062904476.1\|1453948_1456120_+\|protease	ATP-dependent zinc metalloprotease FtsH	A0A0P0BXI2	Ostreococcus_lucimarinus_virus	5.3e-105	44.5
WP_062916670.1\|1456242_1457127_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_046871927.1\|1457260_1458268_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_062916672.1\|1458341_1459835_+\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	3.3e-90	37.7
WP_062904581.1\|1459926_1461174_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046872061.1\|1467219_1468719_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.3e-70	36.2
WP_062916674.1\|1468851_1469673_+	metallophosphoesterase	NA	NA	NA	NA
WP_046872059.1\|1470149_1471013_-	SH3-like domain-containing protein	NA	NA	NA	NA
WP_046872058.1\|1471516_1473010_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
WP_080945560.1\|1473029_1474340_-	aspartate kinase	NA	NA	NA	NA
WP_056986385.1\|1474255_1476133_-	asparagine synthase (glutamine-hydrolyzing)	A0A1B1ISV2	uncultured_Mediterranean_phage	7.2e-34	32.2
WP_062904474.1\|1476427_1477225_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	3.7e-32	35.0
WP_046872291.1\|1477467_1478835_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_056986621.1\|1478973_1480203_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7

DBSCAN-SWA_11

1532645 : 1637589

Streptococcus_phage(19.05%)

protease,transposase,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081115615.1\|1532645_1533893_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_035181568.1\|1534082_1535354_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_046871069.1\|1535446_1536466_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.8e-111	60.4
WP_046871053.1\|1536491_1538657_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	8.6e-257	60.9
WP_046871054.1\|1538766_1538997_-	redoxin NrdH	X2KRY7	Enterococcus_phage	1.2e-12	44.0
WP_056986262.1\|1539296_1539920_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_046871055.1\|1539909_1540428_+	nucleoside deaminase	A0A0B5J096	Pandoravirus	5.1e-06	39.7
WP_046871056.1\|1540618_1542406_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	7.0e-55	43.6
WP_046871057.1\|1542425_1542740_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_046871058.1\|1542755_1543355_+	recombination protein RecR	NA	NA	NA	NA
WP_046871059.1\|1543419_1544073_+	dTMP kinase	M1PSC7	Streptococcus_phage	7.2e-50	49.5
WP_056986263.1\|1544078_1544408_+	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_046871060.1\|1544431_1545439_+	DNA polymerase III subunit delta'	NA	NA	NA	NA
WP_046871061.1\|1545477_1545822_+	DNA replication initiation control protein YabA	NA	NA	NA	NA
WP_080945500.1\|1545808_1546726_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.2e-85	58.4
WP_056986264.1\|1546880_1547639_+	hypothetical protein	NA	NA	NA	NA
WP_046871064.1\|1547702_1548698_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	2.5e-54	40.0
WP_046871065.1\|1548813_1549539_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_046871066.1\|1549522_1550098_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_046871067.1\|1550105_1551143_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	7.0e-63	42.3
WP_056986265.1\|1551163_1552159_+	serine hydrolase	NA	NA	NA	NA
WP_062904469.1\|1552651_1554037_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.1e-28	27.2
WP_046872399.1\|1554132_1556073_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.2e-52	31.2
WP_046872395.1\|1556195_1556819_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_056986412.1\|1556820_1557477_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_046872397.1\|1557662_1557947_+	co-chaperone GroES	A7KV50	Bacillus_phage	9.2e-10	33.7
WP_046872398.1\|1557979_1559620_+	chaperonin GroEL	A0A240F766	uncultured_virus	2.9e-148	53.6
WP_062903827.1\|1559919_1561755_+	APC family permease	NA	NA	NA	NA
WP_035181568.1\|1561831_1563103_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_080945555.1\|1563486_1564710_+	undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	NA	NA	NA	NA
WP_046871894.1\|1565274_1565913_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	1.7e-43	43.3
WP_062916680.1\|1565961_1567299_+	DNA/RNA helicase	A0A1X9I5S6	Streptococcus_phage	1.7e-77	41.3
WP_158231700.1\|1567450_1567966_+	ComF family protein	NA	NA	NA	NA
WP_046871896.1\|1568108_1568675_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_046871897.1\|1568933_1571300_+	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_192868910.1\|1571393_1572509_+	peptide chain release factor 2	NA	NA	NA	NA
WP_056986387.1\|1572542_1573262_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.7e-39	36.5
WP_158509293.1\|1573305_1574661_+	PAS domain-containing protein	W8CYF6	Bacillus_phage	1.4e-23	29.5
WP_062904406.1\|1574819_1576067_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	4.1e-09	24.7
WP_046871901.1\|1576299_1577166_+	phosphate ABC transporter substrate-binding protein PstS family protein	E3SM63	Prochlorococcus_phage	3.2e-05	27.4
WP_046871902.1\|1577171_1578095_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_046871903.1\|1578091_1578979_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_056986245.1\|1578994_1579798_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.5e-15	29.1
WP_046871905.1\|1579865_1580621_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.4e-22	32.3
WP_046871906.1\|1580639_1581317_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_056986246.1\|1581563_1581905_+	PspC domain-containing protein	NA	NA	NA	NA
WP_046871908.1\|1582009_1582372_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_046871909.1\|1582402_1583344_+	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_046871910.1\|1583359_1584202_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_056986247.1\|1584271_1585288_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_046871912.1\|1585344_1586253_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.5e-72	49.7
WP_046871913.1\|1586416_1587358_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	9.7e-80	48.2
WP_081213086.1\|1587501_1587684_-\|transposase	transposase	NA	NA	NA	NA
WP_003555349.1\|1587792_1588530_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_003555353.1\|1588539_1589763_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_062916683.1\|1589849_1590884_-\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	7.8e-06	26.7
WP_056986248.1\|1591181_1592909_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.1e-185	55.5
WP_046871915.1\|1592933_1593563_+	HD domain-containing protein	NA	NA	NA	NA
WP_046871916.1\|1593760_1595764_+	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_046871917.1\|1595775_1598643_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	3.2e-307	56.0
WP_056986066.1\|1598829_1599723_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	5.0e-09	28.8
WP_046871919.1\|1599719_1600730_+	YvcK family protein	A1IMD5	Streptococcus_phage	2.0e-94	55.6
WP_046871920.1\|1600767_1601697_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	2.7e-50	38.4
WP_046871572.1\|1601758_1602355_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	6.8e-55	53.8
WP_056986067.1\|1602934_1604269_+	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_062916686.1\|1604471_1605500_+	SorC family transcriptional regulator	NA	NA	NA	NA
WP_046871570.1\|1605566_1606589_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_046871569.1\|1606714_1607917_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_046871568.1\|1607999_1608755_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_046871567.1\|1608826_1610146_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.2e-171	68.0
WP_062904581.1\|1610564_1611812_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046871566.1\|1611965_1613480_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_046871565.1\|1613604_1615170_+	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
WP_056986069.1\|1615284_1615521_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_062916688.1\|1615593_1617966_+	ribonuclease R	Q0GXV6	Lactococcus_phage	4.2e-87	39.0
WP_046871562.1\|1617979_1618453_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.3e-44	59.1
WP_062916690.1\|1618516_1619944_-	APC family permease	NA	NA	NA	NA
WP_046871560.1\|1620074_1620641_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046871559.1\|1620653_1621226_-	hypothetical protein	NA	NA	NA	NA
WP_046871558.1\|1621255_1622128_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_046871557.1\|1622262_1622985_+	uracil-DNA glycosylase	E2IUG8	Saimiriine_herpesvirus	2.3e-41	43.2
WP_046871556.1\|1622988_1623459_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_046871555.1\|1623455_1623965_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046871554.1\|1623957_1624494_-	3'-5' exonuclease	A0A0A8WJ41	Clostridium_phage	3.6e-07	25.6
WP_046871553.1\|1624598_1625513_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_046871552.1\|1625597_1626545_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_056986070.1\|1626591_1627236_-	DUF1361 domain-containing protein	NA	NA	NA	NA
WP_046870830.1\|1627456_1628308_+	TIGR00159 family protein	NA	NA	NA	NA
WP_056986071.1\|1628304_1629162_+	hypothetical protein	NA	NA	NA	NA
WP_046870828.1\|1629186_1630551_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_046870827.1\|1630776_1632597_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	9.9e-105	39.6
WP_056986072.1\|1632842_1633979_+	glucosaminidase domain-containing protein	H7BVI1	unidentified_phage	5.0e-06	32.3
WP_080945482.1\|1633947_1634127_+	SH3-like domain-containing protein	NA	NA	NA	NA
WP_046870826.1\|1634541_1634847_+	hypothetical protein	NA	NA	NA	NA
WP_056986073.1\|1635236_1636613_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.0e-12	26.9
WP_046870824.1\|1636887_1637589_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_12

1652096 : 1684869

Lactobacillus_phage(46.15%)

integrase,head,bacteriocin,transposase,terminase,capsid,tail,portal

attL 1654962:1655021|attR 1683445:1684994

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904581.1\|1652096_1653344_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046870809.1\|1653450_1654317_-	fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_062904457.1\|1654671_1655022_+	EamA family transporter	NA	NA	NA	NA
1654962:1655021	attL	NA	NA	NA	NA
WP_046872291.1\|1655018_1656386_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_081115584.1\|1656481_1657099_+	hypothetical protein	NA	NA	NA	NA
WP_046870807.1\|1657259_1658615_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_056986351.1\|1658814_1659657_+	hypothetical protein	NA	NA	NA	NA
WP_046870805.1\|1659792_1660125_+	toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_046870833.1\|1660383_1661217_+	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_046870804.1\|1661502_1661712_-	hypothetical protein	NA	NA	NA	NA
WP_046870803.1\|1661704_1662034_-	hypothetical protein	NA	NA	NA	NA
WP_062916693.1\|1662373_1663525_-\|integrase	site-specific integrase	U3PCM7	Lactobacillus_phage	1.1e-40	33.9
WP_062916696.1\|1663582_1664224_-	transcriptional regulator	L0P7E1	Lactobacillus_phage	7.7e-12	56.1
WP_062916698.1\|1664358_1664556_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_062903804.1\|1664572_1664845_+	hypothetical protein	NA	NA	NA	NA
WP_062916700.1\|1665039_1665393_+	hypothetical protein	NA	NA	NA	NA
WP_062916702.1\|1665389_1667771_+	hypothetical protein	Q9T0Y1	Lactobacillus_phage	2.4e-106	32.7
WP_062916704.1\|1668112_1668391_+	hypothetical protein	NA	NA	NA	NA
WP_062916706.1\|1668419_1668755_+\|head	phage head closure protein	NA	NA	NA	NA
WP_062916818.1\|1668763_1669129_+	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	9.1e-18	40.9
WP_062916708.1\|1669387_1669861_+\|terminase	phage terminase small subunit P27 family	M1PKP2	Streptococcus_phage	1.4e-10	30.5
WP_062916710.1\|1669853_1671563_+\|terminase	terminase large subunit	E9LUI0	Lactobacillus_phage	3.9e-119	41.9
WP_062916713.1\|1671528_1671708_+	hypothetical protein	NA	NA	NA	NA
WP_062916715.1\|1671710_1672898_+\|portal	phage portal protein	A0A1W6JPW5	Staphylococcus_phage	1.7e-57	35.1
WP_062916718.1\|1672897_1674451_+\|capsid	phage major capsid protein	B8R651	Lactobacillus_phage	1.3e-36	23.3
WP_062916720.1\|1674516_1674798_+\|head,tail	phage gp6-like head-tail connector protein	Q6J1Y1	Lactobacillus_phage	8.6e-08	37.6
WP_046870802.1\|1675756_1676092_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_003555353.1\|1676720_1677944_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_003555349.1\|1677953_1678691_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_062904456.1\|1678770_1679097_+	DUF2712 domain-containing protein	NA	NA	NA	NA
WP_046870800.1\|1679170_1679971_+	hypothetical protein	NA	NA	NA	NA
WP_046870799.1\|1679960_1680683_+	hypothetical protein	NA	NA	NA	NA
WP_046870798.1\|1680666_1681377_+	hypothetical protein	NA	NA	NA	NA
WP_046870797.1\|1681378_1682032_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.9e-26	34.3
WP_046870796.1\|1682223_1682886_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_056986560.1\|1682886_1683465_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_046872291.1\|1683501_1684869_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
1683445:1684994	attR	NA	NA	NA	NA

DBSCAN-SWA_13

1732759 : 1784330

Mycobacterium_phage(18.75%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904581.1\|1732759_1734007_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_056986085.1\|1734183_1735329_+	cysteine desulfurase	NA	NA	NA	NA
WP_046871374.1\|1735359_1736577_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_046871373.1\|1736671_1737178_+	peroxiredoxin	NA	NA	NA	NA
WP_056986084.1\|1737451_1740115_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	1.7e-161	42.7
WP_080945520.1\|1740160_1741540_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_046871402.1\|1741629_1742244_+	DNA repair protein RadC	NA	NA	NA	NA
WP_056986083.1\|1742397_1743243_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_056986082.1\|1743267_1743813_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_046870896.1\|1744265_1744916_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_046870897.1\|1744928_1745564_+	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.3e-23	32.1
WP_056986081.1\|1745582_1746434_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046870899.1\|1746606_1747878_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	5.5e-54	32.3
WP_062916728.1\|1747870_1749175_+	insulinase family protein	NA	NA	NA	NA
WP_046870901.1\|1749171_1749897_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_046870902.1\|1749966_1750845_+	DUF4115 domain-containing protein	NA	NA	NA	NA
WP_046870903.1\|1750859_1751444_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_062904448.1\|1751550_1752774_+	competence/damage-inducible protein A	NA	NA	NA	NA
WP_062916730.1\|1752863_1753988_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.8e-120	63.9
WP_056986077.1\|1754209_1755769_+	ribonuclease Y	NA	NA	NA	NA
WP_046870907.1\|1755926_1758566_+	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	6.1e-39	25.1
WP_046870908.1\|1758580_1760536_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	9.4e-61	30.8
WP_046870909.1\|1760603_1761197_+	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_046870910.1\|1761214_1762234_+	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	2.8e-08	29.7
WP_046870911.1\|1762309_1763452_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.3e-83	45.8
WP_046870914.1\|1763511_1763934_+	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_062904581.1\|1764053_1765301_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_056986076.1\|1765521_1767015_+	glucose-6-phosphate dehydrogenase	M4SIY3	Cyanophage	1.6e-68	33.3
WP_162261346.1\|1767237_1768329_+	DNA polymerase IV	NA	NA	NA	NA
WP_056986623.1\|1768442_1769819_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_046872062.1\|1770161_1771124_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_062904444.1\|1771127_1772504_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	7.3e-44	30.3
WP_046872064.1\|1772752_1775392_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.1e-64	33.8
WP_056986406.1\|1775511_1775811_+	IreB family regulatory phosphoprotein	NA	NA	NA	NA
WP_046872066.1\|1775807_1776248_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_056986408.1\|1776257_1776551_+	DUF1292 domain-containing protein	NA	NA	NA	NA
WP_046872074.1\|1776705_1779063_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.8e-26	56.1
WP_046872068.1\|1779148_1779460_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	2.1e-15	41.0
WP_062904581.1\|1779623_1780871_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046872291.1\|1781176_1782544_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_056986566.1\|1782696_1782846_+	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_062916733.1\|1782875_1783058_+	hypothetical protein	NA	NA	NA	NA
WP_035181568.1\|1783058_1784330_-\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_14

1788741 : 1843550

Streptococcus_phage(25.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_145913122.1\|1788741_1789137_-\|transposase	transposase	NA	NA	NA	NA
WP_003555353.1\|1789229_1790453_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_003555349.1\|1790462_1791200_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_062904442.1\|1791234_1792125_-\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	6.7e-06	26.7
WP_046872443.1\|1792352_1793171_+	glutamate racemase	NA	NA	NA	NA
WP_181407286.1\|1793173_1793770_+	XTP/dITP diphosphatase	A0A2P1DNN4	Cassava_brown_streak_virus	1.7e-13	33.5
WP_052694571.1\|1793807_1794698_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_046872442.1\|1794838_1795240_+	DUF948 domain-containing protein	NA	NA	NA	NA
WP_046872441.1\|1795260_1795647_+	hypothetical protein	NA	NA	NA	NA
WP_062904581.1\|1795848_1797096_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046871676.1\|1797175_1798273_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_046871677.1\|1798468_1799473_+	catabolite control protein A	NA	NA	NA	NA
WP_062916737.1\|1800075_1801248_+	PLP-dependent transferase	NA	NA	NA	NA
WP_046871679.1\|1801267_1802566_+	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase	NA	NA	NA	NA
WP_100078183.1\|1803553_1804150_+	C39 family peptidase	NA	NA	NA	NA
WP_081213095.1\|1804655_1805474_+	C40 family peptidase	NA	NA	NA	NA
WP_046872291.1\|1805788_1807156_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_056986289.1\|1807556_1808594_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	9.1e-63	39.7
WP_046872380.1\|1808658_1809507_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.2e-31	36.6
WP_046872381.1\|1809638_1810676_+	LCP family protein	NA	NA	NA	NA
WP_062916750.1\|1810811_1811951_+	ATP-binding protein	NA	NA	NA	NA
WP_145974417.1\|1811974_1812292_+	hypothetical protein	NA	NA	NA	NA
WP_056986286.1\|1812430_1812946_-	VanZ family protein	NA	NA	NA	NA
WP_046872383.1\|1813008_1813551_-	VanZ family protein	NA	NA	NA	NA
WP_046872513.1\|1813766_1814222_+	hypothetical protein	NA	NA	NA	NA
WP_046872511.1\|1814830_1816486_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_158510060.1\|1816850_1817723_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.7e-10	32.8
WP_046872509.1\|1817738_1817969_+	hypothetical protein	NA	NA	NA	NA
WP_062904581.1\|1818163_1819411_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_062916820.1\|1819848_1821720_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.3e-101	35.5
WP_046872508.1\|1821825_1822059_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_081036082.1\|1822312_1823692_+	purine permease	NA	NA	NA	NA
WP_056986623.1\|1823918_1825295_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_046872082.1\|1825600_1826725_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A0N9R0B2	Chrysochromulina_ericina_virus	1.4e-24	27.2
WP_046872083.1\|1826731_1827151_+	GtrA family protein	NA	NA	NA	NA
WP_046872084.1\|1827181_1827643_-	flavodoxin	NA	NA	NA	NA
WP_056986459.1\|1827899_1828721_+	recombination regulator RecX	NA	NA	NA	NA
WP_052694544.1\|1828744_1829944_+	serine hydrolase	NA	NA	NA	NA
WP_046872086.1\|1830091_1830649_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_062904440.1\|1830952_1832059_+	AI-2E family transporter	NA	NA	NA	NA
WP_046872088.1\|1832168_1832579_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	7.3e-16	40.7
WP_062913321.1\|1832802_1834008_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	7.0e-75	46.9
WP_046871849.1\|1834357_1835197_+	hypothetical protein	NA	NA	NA	NA
WP_046871848.1\|1837266_1838844_+	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	3.7e-31	26.3
WP_046871847.1\|1839077_1841210_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.7e-146	45.4
WP_056986369.1\|1841306_1843550_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.3e-122	39.9

DBSCAN-SWA_15

1920555 : 2029705

108

Mycobacterium_phage(11.76%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_056985992.1\|1920555_1922532_+\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	5.0e-94	31.7
WP_046872291.1\|1922652_1924020_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_062916822.1\|1924298_1924799_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	1.4e-16	43.1
WP_046871233.1\|1924818_1925022_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_046871234.1\|1925076_1925433_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_046871235.1\|1925543_1926494_-	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_046871236.1\|1926706_1927234_+	YqeG family HAD IIIA-type phosphatase	NA	NA	NA	NA
WP_056986121.1\|1927234_1928347_+	ribosome biogenesis GTPase YqeH	NA	NA	NA	NA
WP_046871238.1\|1928364_1928676_+	YhbY family RNA-binding protein	NA	NA	NA	NA
WP_081115577.1\|1928699_1929344_+	nicotinate-nucleotide adenylyltransferase	G3MA22	Bacillus_virus	7.2e-18	26.9
WP_046871240.1\|1929330_1929936_+	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	NA	NA	NA	NA
WP_056986120.1\|1929947_1930307_+	ribosome silencing factor	NA	NA	NA	NA
WP_062916757.1\|1930303_1931038_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_046871243.1\|1931046_1932168_+	nucleotidyltransferase	NA	NA	NA	NA
WP_046871244.1\|1932242_1932788_+	DUF177 domain-containing protein	NA	NA	NA	NA
WP_046871245.1\|1932849_1933032_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_046871246.1\|1933184_1934603_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	2.5e-39	28.5
WP_046871247.1\|1934798_1935485_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-27	30.2
WP_046871248.1\|1935481_1937023_+	HAMP domain-containing protein	Q8QNA2	Ectocarpus_siliculosus_virus	1.6e-10	28.8
WP_046871249.1\|1937066_1937993_-	membrane protein insertase YidC	NA	NA	NA	NA
WP_046871250.1\|1938065_1938338_-	acylphosphatase	NA	NA	NA	NA
WP_046871251.1\|1938504_1939281_+	RNA methyltransferase	NA	NA	NA	NA
WP_046871252.1\|1939405_1939906_+	hydrolase	NA	NA	NA	NA
WP_046871253.1\|1939933_1940284_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_046871640.1\|1940591_1941638_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	9.0e-26	38.7
WP_046871641.1\|1941646_1944070_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_046871642.1\|1944171_1945293_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_046871643.1\|1945310_1945973_+	uridine kinase	A0A1V0SAA3	Catovirus	2.1e-33	36.1
WP_046871644.1\|1946046_1946532_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_046871645.1\|1946592_1949247_-	YfhO family protein	NA	NA	NA	NA
WP_100078258.1\|1949382_1951437_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_080945532.1\|1951632_1951782_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_046871647.1\|1951865_1952420_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_062904430.1\|1952422_1953103_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_046871649.1\|1953163_1953385_+	YqgQ family protein	NA	NA	NA	NA
WP_046871650.1\|1953403_1954366_+	ROK family glucokinase	NA	NA	NA	NA
WP_062904406.1\|1954483_1955731_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	4.1e-09	24.7
WP_100078185.1\|1956064_1956358_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_080945533.1\|1956495_1956672_-	DUF3042 family protein	NA	NA	NA	NA
WP_046871652.1\|1956761_1957496_+	glycerophosphodiester phosphodiesterase	A0A2H4PGQ5	Escherichia_phage	4.7e-13	42.3
WP_046871653.1\|1957497_1958424_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_046871654.1\|1958426_1959680_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_046871655.1\|1959774_1960149_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_046871656.1\|1960185_1961529_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_046871657.1\|1961785_1962664_+	hypothetical protein	NA	NA	NA	NA
WP_056986415.1\|1962656_1963598_+	hypothetical protein	NA	NA	NA	NA
WP_046871659.1\|1963615_1964155_+	dUTP diphosphatase	A0A1L2JY27	Aeribacillus_phage	1.3e-09	31.0
WP_003555349.1\|1964923_1965661_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_003555353.1\|1965670_1966894_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_062904581.1\|1967146_1968394_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046872108.1\|1968925_1969438_+	hypothetical protein	NA	NA	NA	NA
WP_046872100.1\|1971203_1971665_+	GNAT family N-acetyltransferase	E9LUK4	Lactobacillus_phage	7.2e-28	42.0
WP_056986594.1\|1971790_1972192_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_046872291.1\|1972248_1973616_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_158510061.1\|1973813_1973975_+	TetR/AcrR family transcriptional regulator C-terminal domain-containing protein	NA	NA	NA	NA
WP_046872102.1\|1974122_1974431_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_046872103.1\|1974446_1974785_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_046872104.1\|1974805_1975093_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_046872105.1\|1975243_1975801_+	elongation factor P	NA	NA	NA	NA
WP_046872106.1\|1975820_1976252_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_046872107.1\|1976248_1976653_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_046872141.1\|1976749_1977613_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.3e-33	36.1
WP_046872142.1\|1977605_1978958_+	exodeoxyribonuclease VII large subunit	L7RDW5	Acanthamoeba_polyphaga_moumouvirus	2.1e-27	31.2
WP_046872143.1\|1978950_1979217_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_046872144.1\|1979209_1980112_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_056986361.1\|1980108_1980936_+	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_046872146.1\|1980952_1981408_+	ArgR family transcriptional regulator	NA	NA	NA	NA
WP_062916759.1\|1981442_1983131_+	DNA repair protein RecN	NA	NA	NA	NA
WP_081036088.1\|1983273_1984467_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	8.1e-15	32.4
WP_062904426.1\|1984463_1985099_+	ABC transporter permease	NA	NA	NA	NA
WP_046872150.1\|1985111_1986047_+	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046872151.1\|1986049_1986721_+	ABC transporter permease	NA	NA	NA	NA
WP_046872152.1\|1986722_1987055_-	hypothetical protein	NA	NA	NA	NA
WP_046872153.1\|1987217_1987832_+	guanylate kinase	A0A218KC48	Bacillus_phage	2.4e-10	29.5
WP_046872154.1\|1987833_1988043_+	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_046872155.1\|1988114_1989335_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	2.8e-47	34.0
WP_062904307.1\|1989348_1991763_+	primosomal protein N'	NA	NA	NA	NA
WP_046872156.1\|1991778_1992729_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	3.0e-12	35.1
WP_046872157.1\|1992725_1994057_+	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_046872158.1\|1994063_1994807_+	Stp1/IreP family PP2C-type Ser/Thr phosphatase	R4ZGL0	Mythimna_separata_entomopoxvirus	3.3e-06	26.8
WP_056986329.1\|1994807_1996298_+	Stk1 family PASTA domain-containing Ser/Thr kinase	S4VYI4	Pandoravirus	6.6e-22	34.2
WP_056986328.1\|1996313_1997231_+	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_046872161.1\|1997233_1997890_+	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_046872162.1\|1997889_1998534_+	thiamine diphosphokinase	NA	NA	NA	NA
WP_062904424.1\|1998718_1999966_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	4.1e-09	24.7
WP_046870836.1\|2000044_2000230_-	50S ribosomal protein L28	NA	NA	NA	NA
WP_046870837.1\|2000647_2001010_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_056986508.1\|2001088_2002723_+	DAK2 domain-containing protein	NA	NA	NA	NA
WP_046870838.1\|2002783_2004838_+	ATP-dependent DNA helicase RecG	A0A0C5KL28	Enterococcus_phage	2.6e-05	28.8
WP_056986621.1\|2004985_2006215_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7
WP_046870839.1\|2006565_2007582_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_081213090.1\|2007653_2008052_+	acyl carrier protein	A0A1L2CUN7	Pectobacterium_phage	9.6e-05	37.8
WP_062904581.1\|2008037_2009285_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046870841.1\|2009553_2010255_+	ribonuclease III	A0A1V0SDK0	Indivirus	5.3e-22	36.5
WP_062916762.1\|2010273_2013822_+	chromosome segregation protein SMC	NA	NA	NA	NA
WP_080945484.1\|2013839_2014973_+	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
WP_046870843.1\|2014988_2015330_+	putative DNA-binding protein	NA	NA	NA	NA
WP_046870844.1\|2015347_2016781_+	signal recognition particle protein	NA	NA	NA	NA
WP_046870845.1\|2017039_2018107_+	hypothetical protein	NA	NA	NA	NA
WP_056986148.1\|2018214_2019039_-	serine/threonine protein phosphatase	A0A060ALG7	Listeria_phage	3.6e-14	27.2
WP_046870597.1\|2019368_2020361_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_046870596.1\|2020367_2021864_-	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	2.2e-17	24.6
WP_046870595.1\|2022045_2023719_+	alpha-glucosidase	NA	NA	NA	NA
WP_046870594.1\|2023722_2025663_+	PTS sugar transporter subunit IIBCA	NA	NA	NA	NA
WP_003555353.1\|2025826_2027050_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.9e-107	51.7
WP_003555349.1\|2027059_2027797_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	7.4e-59	50.4
WP_062916765.1\|2027985_2028618_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_062916767.1\|2028775_2029705_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	6.5e-20	29.9

DBSCAN-SWA_16

2039849 : 2103703

Streptococcus_phage(20.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062916774.1\|2039849_2041217_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_056986583.1\|2041510_2042437_+	1-phosphofructokinase	NA	NA	NA	NA
WP_062916776.1\|2042457_2044428_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_056986585.1\|2044551_2045739_-	hypothetical protein	NA	NA	NA	NA
WP_056986621.1\|2046089_2047319_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7
WP_062916778.1\|2047619_2048807_+	amidohydrolase family protein	NA	NA	NA	NA
WP_056986546.1\|2048828_2050031_+	amidohydrolase family protein	NA	NA	NA	NA
WP_056986544.1\|2050183_2050858_+	DUF969 domain-containing protein	NA	NA	NA	NA
WP_056986542.1\|2050850_2051774_+	DUF979 domain-containing protein	NA	NA	NA	NA
WP_056986540.1\|2051791_2052439_+	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_046870591.1\|2052498_2053602_-	acyltransferase	NA	NA	NA	NA
WP_100212720.1\|2053779_2054541_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_046870590.1\|2054646_2055516_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_046870589.1\|2055645_2056563_+	acyltransferase domain-containing protein	NA	NA	NA	NA
WP_046870588.1\|2056682_2058326_+	malonate decarboxylase subunit alpha	NA	NA	NA	NA
WP_052694439.1\|2058347_2059163_+	triphosphoribosyl-dephospho-CoA synthase	NA	NA	NA	NA
WP_046870587.1\|2059164_2059464_+	malonate decarboxylase subunit delta	NA	NA	NA	NA
WP_046870586.1\|2059453_2061121_+	biotin-independent malonate decarboxylase subunit beta	NA	NA	NA	NA
WP_052694438.1\|2061123_2061747_+	malonate decarboxylase holo-ACP synthase	NA	NA	NA	NA
WP_046870584.1\|2061819_2062614_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_046870583.1\|2063265_2064504_+	hypothetical protein	NA	NA	NA	NA
WP_062904581.1\|2064650_2065898_-\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	5.3e-09	24.7
WP_046870582.1\|2066188_2066740_-	hypothetical protein	NA	NA	NA	NA
WP_046870581.1\|2067001_2068006_+	3'-5' exonuclease	A0A0A7RWA3	Clostridium_phage	8.6e-18	30.0
WP_046870580.1\|2068616_2068889_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_046870579.1\|2068904_2069162_+	KH domain-containing protein	NA	NA	NA	NA
WP_056986519.1\|2069212_2069734_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_046870577.1\|2069730_2070486_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_056986521.1\|2070614_2070962_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_046870599.1\|2071077_2072094_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.5e-41	34.0
WP_080945593.1\|2073911_2074118_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_062916780.1\|2074172_2074985_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_046872537.1\|2075087_2076443_+	RsmF rRNA methyltransferase first C-terminal domain-containing protein	NA	NA	NA	NA
WP_062916782.1\|2076497_2077538_-	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_056986135.1\|2077550_2078627_-	phosphomevalonate kinase	NA	NA	NA	NA
WP_056986134.1\|2078659_2079625_-	diphosphomevalonate decarboxylase	NA	NA	NA	NA
WP_046871787.1\|2079599_2080574_-	mevalonate kinase	NA	NA	NA	NA
WP_062904418.1\|2080902_2083776_+	DEAD/DEAH box helicase	A0A1X9I5C8	Streptococcus_phage	2.2e-58	34.1
WP_046871786.1\|2083840_2084335_+	DUF5590 domain-containing protein	NA	NA	NA	NA
WP_046871779.1\|2084363_2085665_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	2.1e-56	30.4
WP_046871778.1\|2085686_2086412_+	DnaD domain protein	A0A0N7AE27	Bacillus_phage	4.9e-15	36.3
WP_056986133.1\|2086484_2088767_-	penicillin-binding protein	NA	NA	NA	NA
WP_056986132.1\|2088756_2089392_-	Holliday junction resolvase RecU	A0A2H4J3A4	uncultured_Caudovirales_phage	1.4e-21	36.5
WP_046871775.1\|2089480_2090050_+	DUF1273 domain-containing protein	NA	NA	NA	NA
WP_046871774.1\|2090109_2090451_+	cell division regulator GpsB	NA	NA	NA	NA
WP_046871773.1\|2090918_2092076_+	class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_158231967.1\|2092062_2093181_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_046871771.1\|2093180_2093600_+	EbsA family protein	NA	NA	NA	NA
WP_046871770.1\|2093596_2095255_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_046871785.1\|2095275_2095731_+	signal peptidase II	NA	NA	NA	NA
WP_062916784.1\|2095732_2096644_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	2.1e-10	27.4
WP_172793939.1\|2096786_2097308_+	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_062916786.1\|2097326_2098409_+	carbamoyl phosphate synthase small subunit	NA	NA	NA	NA
WP_056986130.1\|2098410_2100867_+	carbamoyl phosphate synthase large subunit	NA	NA	NA	NA
WP_062904414.1\|2101008_2102256_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	7.0e-09	24.7
WP_035181568.1\|2102431_2103703_+\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_17

2139828 : 2149735

Staphylococcus_phage(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_056986001.1\|2139828_2141259_-	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	7.2e-26	32.8
WP_046871118.1\|2141270_2141501_-	YozE family protein	NA	NA	NA	NA
WP_046871117.1\|2141511_2142117_-	YpmS family protein	NA	NA	NA	NA
WP_046871116.1\|2142122_2143061_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_056985999.1\|2143165_2144011_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	8.9e-16	33.6
WP_046871114.1\|2144080_2144596_-	dihydrofolate reductase	S5M436	Bacillus_phage	3.5e-23	42.8
WP_046871113.1\|2144614_2145565_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	5.0e-116	62.4
WP_046871112.1\|2145583_2147485_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.8e-53	30.5
WP_046871111.1\|2147491_2148715_-\|tRNA	CCA tRNA nucleotidyltransferase	G3MAR3	Bacillus_virus	7.7e-37	43.0
WP_046871138.1\|2148859_2149735_+	YitT family protein	M1Q1P6	Streptococcus_phage	1.3e-54	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP012289

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

901 : 9528

Bacillus_phage(50.0%)

transposase,terminase,integrase

attL 2456:2469|attR 6358:6371

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158509302.1\|901_1459_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.3e-26	39.1
WP_158510062.1\|1499_1661_-	hypothetical protein	NA	NA	NA	NA
WP_062904581.1\|1857_3105_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.0e-39	30.5
2456:2469	attL	NA	NA	NA	NA
WP_001748110.1\|3673_4018_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_003643337.1\|4011_4275_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_062904616.1\|4360_4948_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	1.1e-20	33.2
WP_052694451.1\|5763_6378_+	HNH endonuclease	A8YQN4	Lactobacillus_phage	1.6e-11	28.7
6358:6371	attR	NA	NA	NA	NA
WP_062904617.1\|6575_7034_+\|terminase	phage terminase small subunit P27 family	E9LUP8	Lactobacillus_phage	2.8e-80	96.1
WP_155386924.1\|7047_7200_-	hypothetical protein	NA	NA	NA	NA
WP_046870702.1\|7186_7606_-	hypothetical protein	NA	NA	NA	NA
WP_062904618.1\|7920_9528_-	hypothetical protein	A0A1B1P7L5	Bacillus_phage	1.2e-24	28.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP012290

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 4695

Staphylococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075168805.1\|1804_2683_-	glycosyl transferase	NA	NA	NA	NA
WP_191982121.1\|2729_3716_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.1e-45	36.9
WP_056986352.1\|4113_4695_-	recombinase family protein	M9Q1K0	Clostridium_phage	9.1e-20	34.9

DBSCAN-SWA_2

8778 : 9651

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046870601.1\|8778_9651_+	N-acetylmuramoyl-L-alanine amidase	A0A067ZJB6	Vibrio_phage	1.1e-16	35.4

DBSCAN-SWA_3

12889 : 13444

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033615067.1\|12889_13444_-	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	6.8e-33	45.1

DBSCAN-SWA_4

35404 : 40446

Clostridium_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_056986383.1\|35404_36196_-	AAA family ATPase	E2ELL2	Clostridium_phage	1.0e-13	25.4
WP_056986382.1\|37180_37381_-	hypothetical protein	NA	NA	NA	NA
WP_155515909.1\|37753_37924_-	hypothetical protein	NA	NA	NA	NA
WP_010619295.1\|38104_39130_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.6e-40	35.2
WP_004561985.1\|39456_40446_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.9e-59	40.5

DBSCAN-SWA_5

45071 : 54104

Streptococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062916853.1\|45071_46310_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	8.4e-39	28.8
WP_056986360.1\|47129_48653_-	primase C-terminal domain-containing protein	NA	NA	NA	NA
WP_042255042.1\|49269_50169_+	AAA family ATPase	A0A0K2FLP4	Brevibacillus_phage	4.2e-16	26.5
WP_042255044.1\|50155_50437_+	hypothetical protein	NA	NA	NA	NA
WP_062916855.1\|50710_51577_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_056986358.1\|51573_52524_-	glycosyltransferase family 8 protein	A0ZYL4	Archaeal_BJ1_virus	3.8e-07	22.4
WP_056986621.1\|52874_54104_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP012292

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012292_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012292_1

9329-9483

Orphan

Consensus_repeat	Method
AATCCCTTGATACAAGCAGACTTCCGAAAAACGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012292_1

>merge|NZ_CP012292|1|9329-9483|CRISPRCasFinder
AATCCCTTGATACGAGCAGACTTCCGAAAAACGGAAATCAGCATGAGACCGTTGAATCCCTTGATACAAGCAGACTTCCGAAAAACGGAAATCAGCATGAGACCGTTGGTAACATATCCCAATCCCTTGATACAAGCAGACTTCCGAAAAACGGA

>NZ_CP012292|1|1|9329-9483|CRISPRCasFinder
AATCCCTTGATACGAGCAGACTTCCGAAAAACGGA	AATCAGCATGAGACCGTTGAATCCCTTGATACAAGCAGACTTCCGAAAAACGGAAATCAGCATGAGACCGTTGGTAACATATCCC
AATCCCTTGATACAAGCAGACTTCCGAAAAACGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012292.1\|WP_054712561.1\|7790_7994_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012292.1\|WP_046870853.1\|11995_12355_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012292.1\|WP_054712567.1\|5109_6033_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP012292.1\|WP_054712564.1\|6950_7736_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NZ_CP012292.1\|WP_065868917.1\|2485_2716_+\|CrcB-family-protein	unknown	unknown	gnl\|CDD\|184571
NZ_CP012292.1\|WP_062916925.1\|13775_14978_-\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341151
NZ_CP012292.1\|WP_075168959.1\|6619_6784_-\|MFS-transporter	unknown	unknown	unknown
NZ_CP012292.1\|WP_011668133.1\|4193_4481_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012292.1\|WP_056986487.1\|4577_5054_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP012292.1\|WP_056986492.1\|2093_2492_+\|CrcB-family-protein	unknown	unknown	gnl\|CDD\|223317
NZ_CP012292.1\|WP_020090510.1\|12367_12955_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271192
NZ_CP012292.1\|WP_027822196.1\|13309_13666_+\|type-II-toxin-antitoxin-system-YafQ-family-toxin	unknown	unknown	gnl\|CDD\|379750
NZ_CP012292.1\|WP_054712554.1\|10162_10360_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012292.1\|WP_062916927.1\|14970_16563_-\|type-I-restriction-modification-system-subunit-M	unknown	unknown	gnl\|CDD\|280533
NZ_CP012292.1\|WP_056986490.1\|2876_3719_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP012292.1\|WP_002834561.1\|13031_13310_+\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NZ_CP012292.1\|WP_046870851.1\|10410_11145_+\|Fic-family-protein	unknown	unknown	gnl\|CDD\|376885
NZ_CP012292.1\|WP_062916929.1\|16590_19563_-\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NZ_CP012292.1\|WP_050894606.1\|11519_11729_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012292.1\|WP_056986488.1\|3759_4023_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366690

Protein	Function_ID	Function_description	E-value
NZ_CP012292.1\|WP_062916925.1\|13775_14978_-\|restriction-endonuclease-subunit-S	gnl\|CDD\|341151	cd17262, RMtype1_S_Aco12261I-TRD2-CR2, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Aminobacterium colombiense DSM 12261 S subunit (S.Aco12261I) TRD2-CR2 and Moraxella catarrhalis S subunit (S.Mca353ORF290P) TRD2-CR2. Aminobacterium colombiense DSM 12261 S subunit (S.Aco12261I) recognizes 5'... GCANNNNNNTGT ... 3', and Moraxella catarrhalis S subunit (S.Mca353ORF290P) recognizes 5'... CAAGNNNNNNTGT ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	7.49625e-78
NZ_CP012292.1\|WP_054712567.1\|5109_6033_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	4.45666e-73
NZ_CP012292.1\|WP_054712564.1\|6950_7736_+\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	1.71649e-30
NZ_CP012292.1\|WP_065868917.1\|2485_2716_+\|CrcB-family-protein	gnl\|CDD\|184571	PRK14214, PRK14214, fluoride efflux transporter CrcB.	1.21895e-06
NZ_CP012292.1\|WP_062916927.1\|14970_16563_-\|type-I-restriction-modification-system-subunit-M	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	3.01453e-137
NZ_CP012292.1\|WP_056986488.1\|3759_4023_-\|IS3-family-transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	5.25483e-07
NZ_CP012292.1\|WP_056986487.1\|4577_5054_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.59579e-30
NZ_CP012292.1\|WP_056986492.1\|2093_2492_+\|CrcB-family-protein	gnl\|CDD\|223317	COG0239, CrcB, Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning].	1.0118e-11
NZ_CP012292.1\|WP_027822196.1\|13309_13666_+\|type-II-toxin-antitoxin-system-YafQ-family-toxin	gnl\|CDD\|379750	pfam15738, YafQ_toxin, Bacterial toxin of type II toxin-antitoxin system, YafQ. YafQ is a family of bacterial toxin ribonucleases of type II toxin-antitoxin systems. The E.coli gene is expressed from the dinB operon. The cognate antitoxin for the E. coli protein is DinJ, in family RelB_antitoxin, pfam02604.	5.32308e-22
NZ_CP012292.1\|WP_056986490.1\|2876_3719_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.31698e-138
NZ_CP012292.1\|WP_002834561.1\|13031_13310_+\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	2.51812e-05
NZ_CP012292.1\|WP_046870851.1\|10410_11145_+\|Fic-family-protein	gnl\|CDD\|376885	pfam02661, Fic, Fic/DOC family. This family consists of the Fic (filamentation induced by cAMP) protein and doc (death on curing). The Fic protein is involved in cell division and is suggested to be involved in the synthesis of PAB or folate, indicating that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism. This family contains a central conserved motif HPFXXGNG in most members. The exact molecular function of these proteins is uncertain. P1 lysogens of Escherichia coli carry the prophage as a stable low copy number plasmid. The frequency with which viable cells cured of prophage are produced is about 10(-5) per cell per generation. A significant part of this remarkable stability can be attributed to a plasmid-encoded mechanism that causes death of cells that have lost P1. In other words, the lysogenic cells appear to be addicted to the presence of the prophage. The plasmid withdrawal response depends on a gene named doc (death on curing) that is represented by this family. Doc induces a reversible growth arrest of E. coli cells by targetting the protein synthesis machinery. Doc hosts the C-terminal domain of its antitoxin partner Phd (prevents host death) through fold complementation, a domain that is intrinsically disordered in solution but that folds into an alpha-helix on binding to Doc.This domain forms complexes with Phd antitoxins containing pfam02604.	0.000949229
NZ_CP012292.1\|WP_062916929.1\|16590_19563_-\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	4.89106e-149
NZ_CP012292.1\|WP_020090510.1\|12367_12955_-\|site-specific-integrase	gnl\|CDD\|271192	cd01192, INT_C_like_3, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	1.22618e-72

>NZ_CP012292.1|WP_054712561.1|7790_7994_+|hypothetical-protein
MAFEDKMNQLKNSMSSKPAKNEPTAPRISKSYTLKQDIANELTRRAKEKELTASRYLEKLLKKEFNL
>NZ_CP012292.1|WP_054712564.1|6950_7736_+|ParA-family-protein
MKIITFSAIKGGVGKTTLTFNYGEWLSSKGYNVLMIDSDHQCSLTQTYDIYKDHDTLANVFTKDNEKVEIIELHKNLSIIPASMNLDTINNDLQTRANKELLMYMWFSDNYNELKKFNYVLIDTHPDFSTITQNMIVISDFVFSPIEPSEYGFISKSNLELRMKQLKQDVINVETRQSFVTAELKFIGNRIKHNTKSSHEFVEQMKKDPRTIALIPEREIFNKTTLNHKPLIKMEQENNSTQRAKEFFENIDNIFETFAKQ
>NZ_CP012292.1|WP_075168959.1|6619_6784_-|MFS-transporter
MAQKEALMNSMGKIKHAKKRQISHAFSHTYLVGAVIILILSPIALLTDRKQFKS
>NZ_CP012292.1|WP_054712567.1|5109_6033_-|IS30-family-transposase
MSTTIVSFQNRVVIETLHNEGRSLRYIANYLDFSQTTIFNELHRLNGEYQAELAQTDFERKVSQRGRKSSLTKNLKHLIEEKIQVQKWSPEQVAHVVGIAYKTVYNWIDQGWLDVQLPDLPDHGIRRHRAKEKRGTFSHGRSIEKRPHKIETRQEFGHFEADTVLSGKRKGQAVATFVERKSRLTIVKRLHGRDSQSMTQTVLELARQLQDKLKTLTVDHGKEFANYQTIERRTGTQVYFAHAYSPHERGSNENRNRVLRRFIPKGQAIEELSDHQLVQINWYLNSRPLKCLNWHTPIEIFLLNLRH
>NZ_CP012292.1|WP_056986487.1|4577_5054_+|universal-stress-protein
MLQQYKHILVPVDGSYEAELAFKKAVAVAKRNDADLHLVHVVDTRALQIFSSLDTSMAEQVTETAKKTLDKYVADAKADGLDKIDYAIEYGAPRTIIEDVPRGNDTDLIMIGATGLNAVGRLLIGSVTDYVTRTAVCDVIVVRTDLDNQPAKAAHRAE
>NZ_CP012292.1|WP_011668133.1|4193_4481_+|hypothetical-protein
MAITILMACYTLLALGIGWYFYAHRRRAFLVFHPESSHELSRVLTISGVVMLLIGVLSAVATIMNNMVFISTMLLVGVIAIISIQLILLHWFPKA
>NZ_CP012292.1|WP_056986488.1|3759_4023_-|IS3-family-transposase
MPTRYDKEFKQNIINLYKQGESAAQLAREYGIGYSTVHKWIQGQAKTQSGKSPDEIKAMEKRLASLSEENEILKKTWASLRRSNQYL
>NZ_CP012292.1|WP_056986490.1|2876_3719_-|IS3-family-transposase
MCRILGVSRAQYYRYRSPKPSKRRAEDEDLKQRILRIFAEFKQRYGVMKIHHEWNLELQPLQRPCSPRRISRLMKELDIHSVTVNKWKAASASKTKVEQRPNLLKQDFSTTGLNQKWTADMTYIQTKRNGWCYLSTIMDLHSRRIIGYSFSKKMDTDLVLKTLESAVKNRTITGDLIIHTDLGSQYTSDDYNQRLTELHIRHSHSRKGCPYDNAPMESFHASLKKECVYPVPVFENYETAAAVLFEYVHAFYNRKRIHSSLGYQTPLQVEIATLTSQMAA
>NZ_CP012292.1|WP_065868917.1|2485_2716_+|CrcB-family-protein
MVMLVTLGAGVGAVMQYVLTQLGKNWWTWVSVATLVINASGAFLAGFLAMCALQQAWSLLLLTGVWWVHDFFHIHD
>NZ_CP012292.1|WP_056986492.1|2093_2492_+|CrcB-family-protein
MQRLRYQDILAMFIGGCFGGIACWEIGLWLNDADTMLGTTAMNLIGRFLLEFVTYGLAVYIDLPGWLILALGTGFVGAFTTFSTMVPNLYKNVGESPVYEIRIFLLELLVGLGAAFSGYLCAEAWGRRRQTW
>NZ_CP012292.1|WP_054712554.1|10162_10360_+|hypothetical-protein
MTKPSKEIETIDQLLADPWAVNIQDIWEQAAHNPDPDKRKLFDALHTYLLDKRQEQIINEKHFVI
>NZ_CP012292.1|WP_046870851.1|10410_11145_+|Fic-family-protein
MAKTRTYMDKYKFTAAENQRFARANFTKLVHTNARFEGVNTTLPQTQTIMDGMSVAGVPVEDVLTIVNLKRGWQYITAQNSPLTLTMEKQINKIVAAEDALVPGELRQGKGGVNLGSDDFFEQPLINEKQEQSFLQKILADPRTTITDKALTVMYHNMRQQIFWDGNKRTATLSANKIMIDGGAGLINVPLDKWDQWNELIANYYRTNDMAKIKRWTYDNGIQGLQIRANLALKSVKDKTSKRI
>NZ_CP012292.1|WP_050894606.1|11519_11729_-|hypothetical-protein
MSQSNLEKQEAKLKQLNQKIKAEKNKIEQNLGKQIIRSANLDYGTLTTPQIKMIAKKVAAFLNQAQNNQ
>NZ_CP012292.1|WP_046870853.1|11995_12355_-|hypothetical-protein
MDLDFKSNKYDLFDDWHQNKTKQAFTQKLQQQAQLEKTQLPQLLSREDLKIRWQMNSRQSVHQVASKPDFPQPVFAFNHGKTPLYLATEIQIFEINHPWVITPGARLAYSHWILRNVID
>NZ_CP012292.1|WP_020090510.1|12367_12955_-|site-specific-integrase
MQQVVLPIKDSNVLKEVQDTLLNNFKAGRRNYTVFQVGKATLLRVSDVMRLKQTDIFNPDGSIKQNAFIHDRKTGKPNTLYLKPVQTELLLYRQWLLDHRLASEWLFPSIQHPERHITEKQFYKIMSKVGDLLGINYLGTHTMRKTGAYRVYTQSNYNIGLVMHLLNHSSEAMTLAYLGLDQASTETMLDKIDFG
>NZ_CP012292.1|WP_002834561.1|13031_13310_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MTLALTQSDFRANLKKYLDQVNDEDETVYIARSNSRAVAIVSQEKMDWLERALKAKEGSLEYAIARDQLIKRHVLPDDEIVESNDDYWGQFK
>NZ_CP012292.1|WP_027822196.1|13309_13666_+|type-II-toxin-antitoxin-system-YafQ-family-toxin
MKKLRFKPRATFNADLKRLASLDKSIIDEVRAAIDLLLEQQQLPPEFEDHELNRRMSGYNEFHLRDTPKNKTPSETNDVLVVYTIDKDELVLIGIRVGSHDRLFPGQNRAKRYRKNDK
>NZ_CP012292.1|WP_062916925.1|13775_14978_-|restriction-endonuclease-subunit-S
MSNKVPQIRFNGYSDAWEDRKLSDIADRFDNLRVPITASDRKPGDTPYYGANGIQDYVEGFTHNGEFILVAEDGANDLKNYPVQYVNGKVWVNNHAHVLQGKKTITDNKFLMNAIKNFKIEPFLVGGGRAKLNADVMMKLNILLPTFVEQEKIGSLFSLLDKTIALHQRKLDLLKEEKKGYLQKMFPKNGAKVPELRFAGFADDWEERKLGDTETHFTDGNYGESYPSAKDMSDKANGIPFLRGSDFSNGYLDSSNANYIKPEKHAELTSGHIKQDDIVLVVRGSLGTLGYATKENEGWNINSQLAILRTNKSEISGMFLIQYLLGSKGQKEIFSRNTGTALKQLPIKQLKDIPVPVPTLLEQQKIGNFFKELDSTIALHQRKLDLLKEQKKGFLQKMFV
>NZ_CP012292.1|WP_062916927.1|14970_16563_-|type-I-restriction-modification-system-subunit-M
MALPADKQALIWKTLNETRGKIEPSEYKNYIFGLMFYKFLSEKAQTWLDSQLRGETWSSVWEQNPEKAAAFMQTKLGYVIQPGELFSDWQAAINVDQFNITNVADALGHFNQGIQPGAKATFEGIFDDMDLASSRLGSNTQTRTKTLMDWISLIDQIELDEDADVLGDLYEYLIGMFAANSGAKAGEFYTPHQVSDIMARILTAGREDMPTYSLYDPAMGSGSLLLTTASYMKNDGVRGAIKYYGQEVITTTYNLGRINLMMHGVEYNDIHIHNADTLSSDWPDGVQSGVDSPRMFDAVMANPPYSLKWDNTNREDDPRFKAGIAPKSKADFAFLQHGLYHLKQDGRMAIVLPHGVLFRGAAEGRIRQALLENRNISAVIGLPEKIFTNTGIPTIIMILEKNRTTDDVLFIDASKGFEKQKNNNKLRQEDVDLIVETFLKREDVAKYAHVASFDEIKENDFNLNIPRYVDTFEEEEPVDLVAVSQDLVDVNRDIAQSESDLLAMISDLAVTEDSQAIIESAKQLLGGKHE
>NZ_CP012292.1|WP_062916929.1|16590_19563_-|type-I-restriction-endonuclease-subunit-R
MAEDKFEQAVIDKLKSEGWEYLTDYSSVTVDRLYDHWRDIMNANNRKRLEDTPLSDNEFEQVKLELTKNKTPYDAQLMLAGAGGVGTVPLNRDDGTQLELEIFYGDEVAGGHSRYEVVNQITFTDLATSLSSKRRIDIMLLINGLPVAHIEEKDESLQNQWNAFEQFQKYDGDGMYTGLFSFVQVQFVLSQNSAHYFARPKNSDSYNRDFAFGWRDDAGKDVTNTMTFIHEVMGIPALHRLVTVNMIPDAANDNLMVMRSYQIQATRQILDRMREMDQNGLVEKEGGYVWHTTGSGKTVTSFKVAQLLASRPRVEDVLFIVDRVDLVNQTYENFKSFAYKTFENRIQVVNGSELKRALKHDNTAHIYLITVQGLDKAIKSGLASNKRMVILMDEAHRSASGDAVSRIKQALPKTTWFGFTGTPNFYSDEVHDVKTSKDVSTHAIFGPCLHRYTIKDAIGDGNVLGFDVTYYETDFEHDMDSGLTEKELEKEVYASLPFRQAVVADIQRNWATNASGPINMGVREPNQFQGMLAVSGKQAVASYYSLFKQLAPELRVAMTYSRDEANGTGASDLQAALKQAMQDYMTFYGTRNFLEDKDPQRAYLNDMTKRIARKKPYNKGNDADRLDLIIVSDQLLTGFDSKFVNIIYMDKILGEGPLIQAMSRTNRTIDKTAKPHGKVRFYRQGAVMEEKVKDALVIYTKGGNDTLADAGNTPDDQEQKDLFDEGILAPKAADKIVDLNPQIKRLQQLAGDDFSQMPRSEKEQVEFAVTAAQVNSQVQQLVQQGYVLGNSVEGPEGPITLGIESATQLSSLQARMNDVNEVLPADKQVDLTNIKLVLQSFANEIIDYDKLVDLLNAYMDEVSVANRAAVEEHVQPLDQDNREEIGQVLDGIEQGEYTEPFTTETLKSVRKAIRTAQQDLKIYKWAADHDYNGNDILAAYELYRPGIPLVDNTALNQYLQDLESHLDIGFFELADFEESLLNYFAKITKK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP012282	Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-7, complete sequence	9364-9448	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP014926	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-2, complete sequence	8117-8201	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP014935	Pediococcus claussenii strain TMW 2.53 plasmid pL253-2, complete sequence	4405-4489	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP014938	Pediococcus claussenii strain TMW 2.54 plasmid pL254-2, complete sequence	4405-4489	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP012292	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-4, complete sequence	9364-9448	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP019747	Lactobacillus brevis strain TMW 1.2111 plasmid pl12111-4, complete sequence	36397-36481	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP014885	Lactobacillus backii strain TMW 1.1991 plasmid pL11991-4, complete sequence	32761-32845	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP014877	Lactobacillus backii strain TMW 1.1989 plasmid pL11989-4, complete sequence	20125-20209	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP014628	Lactobacillus backii strain TMW 1.1988 plasmid L11988-4, complete sequence	11513-11597	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP019738	Lactobacillus brevis strain TMW 1.2108 plasmid pl12108-4, complete sequence	33714-33798	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP018797	Lactobacillus parabuchneri strain FAM21731 plasmid pFAM21731.1, complete sequence	57121-57205	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP014903	Lactobacillus backii strain TMW 1.2002 plasmid pL12002-4, complete sequence	56863-56947	25	0.706
NZ_CP012292_1	1.1\|9364\|85\|NZ_CP012292\|CRISPRCasFinder	9364-9448	85	NZ_CP014895	Lactobacillus backii strain TMW 1.1992 plasmid pL11992-5, complete sequence	20198-20282	25	0.706

1. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP012282 (Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-7, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

2. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP014926 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-2, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

3. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP014935 (Pediococcus claussenii strain TMW 2.53 plasmid pL253-2, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

4. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP014938 (Pediococcus claussenii strain TMW 2.54 plasmid pL254-2, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

5. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP012292 (Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-4, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

6. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP019747 (Lactobacillus brevis strain TMW 1.2111 plasmid pl12111-4, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

7. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP014885 (Lactobacillus backii strain TMW 1.1991 plasmid pL11991-4, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

8. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP014877 (Lactobacillus backii strain TMW 1.1989 plasmid pL11989-4, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

9. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP014628 (Lactobacillus backii strain TMW 1.1988 plasmid L11988-4, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

10. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP019738 (Lactobacillus brevis strain TMW 1.2108 plasmid pl12108-4, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

11. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP018797 (Lactobacillus parabuchneri strain FAM21731 plasmid pFAM21731.1, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

12. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP014903 (Lactobacillus backii strain TMW 1.2002 plasmid pL12002-4, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

13. spacer 1.1|9364|85|NZ_CP012292|CRISPRCasFinder matches to NZ_CP014895 (Lactobacillus backii strain TMW 1.1992 plasmid pL11992-5, complete sequence) position: , mismatch: 25, identity: 0.706

aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	CRISPR spacer
aatcagcatgagaccgttgaatcccttgatacaagcagacttccgaaaaacggaaatcag	Protospacer
************************************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP012291

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012291_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012291_1

111562-111699

Orphan

Consensus_repeat	Method
ATACAAAGATACAAGGATACAAGGATACA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP012291_1

>merge|NZ_CP012291|1|111562-111699|CRISPRCasFinder
ATCCTAATATACAAGGATACTTGGATACAAGGATGATAACATACAAAGATACAAGGATACAAGGATACATTTCTTCTCAAAAGCCGTTAAATTAAGATTGACTGCAAGTATCCTAATATACTTAGATACAAGGATACA

>NZ_CP012291|1|1|111562-111699|CRISPRCasFinder
ATCCTAATATACAAGGATACTTGGATACA	AGGATGATAACATACAAAG
ATACAAGGATACAAGGATACATTTCTTCT	CAAAAGCCGTTAAATTAAGATTGACTGCAAGT
ATCCTAATATACTTAGATACAAGGATACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012291.1\|WP_145974423.1\|118352_118568_-\|transposase	unknown	unknown	gnl\|CDD\|379233
NZ_CP012291.1\|WP_020923847.1\|113825_114104_+\|BRCT-domain-containing-protein	unknown	unknown	gnl\|CDD\|349379
NZ_CP012291.1\|WP_062904602.1\|97665_99432_+\|alpha-glycosidase	unknown	unknown	gnl\|CDD\|200477
NZ_CP012291.1\|WP_062904581.1\|111869_113117_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP012291.1\|WP_062904605.1\|105453_107568_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_CP012291.1\|WP_081115635.1\|103831_104281_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012291.1\|WP_046872572.1\|114497_114872_+\|DUF536-domain-containing-protein	unknown	unknown	unknown
NZ_CP012291.1\|WP_035168888.1\|114284_114485_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012291.1\|WP_046872463.1\|110739_111540_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379293
NZ_CP012291.1\|WP_145974422.1\|116418_116865_+\|SHOCT-domain-containing-protein	unknown	unknown	gnl\|CDD\|378276
NZ_CP012291.1\|WP_062916767.1\|104307_105237_+\|IS30-like-element-ISLpl1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP012291.1\|WP_062904601.1\|96319_97666_+\|SLC45-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340871
NZ_CP012291.1\|WP_062916905.1\|117558_118299_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP012291.1\|WP_081115631.1\|101472_102378_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NZ_CP012291.1\|WP_062916923.1\|120145_121099_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380517
NZ_CP012291.1\|WP_046872462.1\|110387_110738_-\|DUF5388-domain-containing-protein	unknown	unknown	gnl\|CDD\|375154
NZ_CP012291.1\|WP_062904603.1\|100263_101106_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP012291.1\|WP_002816285.1\|99958_100210_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP012291.1\|WP_046872533.1\|116997_117291_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012291.1\|WP_062916907.1\|118709_119741_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382

Protein	Function_ID	Function_description	E-value
NZ_CP012291.1\|WP_020923847.1\|113825_114104_+\|BRCT-domain-containing-protein	gnl\|CDD\|349379	cd17748, BRCT_DNA_ligase_like, BRCT domain of bacterial NAD-dependent DNA ligase (LigA) and similar proteins. LigA, also called NAD(+)-dependent polydeoxyribonucleotide synthase, catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. The Trp-X-X-X-Cys/Ser signature motif of the BRCT family is not conserved in this family.	7.23915e-20
NZ_CP012291.1\|WP_062904602.1\|97665_99432_+\|alpha-glycosidase	gnl\|CDD\|200477	cd11338, AmyAc_CMD, Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins. Cyclomaltodextrinase (CDase; EC3.2.1.54), neopullulanase (NPase; EC 3.2.1.135), and maltogenic amylase (MA; EC 3.2.1.133) catalyze the hydrolysis of alpha-(1,4) glycosidic linkages on a number of substrates including cyclomaltodextrins (CDs), pullulan, and starch. These enzymes hydrolyze CDs and starch to maltose and pullulan to panose by cleavage of alpha-1,4 glycosidic bonds whereas alpha-amylases essentially lack activity on CDs and pullulan. They also catalyze transglycosylation of oligosaccharides to the C3-, C4- or C6-hydroxyl groups of various acceptor sugar molecules. Since these proteins are nearly indistinguishable from each other, they are referred to as cyclomaltodextrinases (CMDs). The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP012291.1\|WP_062904581.1\|111869_113117_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.21343e-46
NZ_CP012291.1\|WP_062904605.1\|105453_107568_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP012291.1\|WP_145974423.1\|118352_118568_-\|transposase	gnl\|CDD\|379233	pfam13518, HTH_28, Helix-turn-helix domain. This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.	0.0022602
NZ_CP012291.1\|WP_062916923.1\|120145_121099_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380517	cd06294, PBP1_MalR-like, ligand-binding domain of maltose transcription regulator MalR which is a member of the LacI-GalR family repressors. This group includes the ligand-binding domain of maltose transcription regulator MalR which is a member of the LacI-GalR family repressors that are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	7.06738e-69
NZ_CP012291.1\|WP_046872463.1\|110739_111540_-\|AAA-family-ATPase	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	1.2288e-43
NZ_CP012291.1\|WP_145974422.1\|116418_116865_+\|SHOCT-domain-containing-protein	gnl\|CDD\|378276	pfam09851, SHOCT, Short C-terminal domain.	3.01434e-06
NZ_CP012291.1\|WP_062916767.1\|104307_105237_+\|IS30-like-element-ISLpl1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.8745e-69
NZ_CP012291.1\|WP_062904601.1\|96319_97666_+\|SLC45-family-MFS-transporter	gnl\|CDD\|340871	cd17313, MFS_SLC45_SUC, Solute carrier family 45 and similar sugar transporters of the Major Facilitator Superfamily of transporters. This group includes the solute carrier 45 (SLC45) family as well as plant sucrose transporters (SUCs or SUTs) and similar proteins such as Schizosaccharomyces pombe general alpha-glucoside permease. the SLC45 family is composed of four (A1-A4) vertebrate proteins as well as related insect proteins such as Drosophila sucrose transporter SCRT or Slc45-1. Members of this group transport sucrose and other sugars like maltose into the cell, with the concomitant uptake of protons (symport system). Plant sucrose transporters are crucial to carbon partitioning, playing a key role in phloem loading/unloading. They play a key role in loading and unloading of sucrose into the phloem and as a result, they control sucrose distribution throughout the whole plant and drive the osmotic flow system in the phloem. They also play a role in the exchange of sucrose between beneficial symbionts (mycorrhiza and Rhizobium) as well as pathogens such as nematodes and parasitic fungi. There are nine sucrose transporter genes in Arabidopsis and five in rice. Vertebrate SLC45 family proteins have been implicated in the regulation of glucose homoeostasis in the brain (SLC45A1), with skin and hair pigmentation (SLC45A2), and with prostate cancer and myelination (SLC45A3). Mutations in SLC45A2, also called MATP (membrane-associated transporter protein) or melanoma antigen AIM1, cause oculocutaneous albinism type 4 (OCA4), an autosomal recessive disorder of melanin biosynthesis that results in congenital hypopigmentation of ocular and cutaneous tissues. The SLC45 family and related sugar transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.74915e-98
NZ_CP012291.1\|WP_062916905.1\|117558_118299_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	8.93385e-124
NZ_CP012291.1\|WP_081115631.1\|101472_102378_+\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.282e-29
NZ_CP012291.1\|WP_046872462.1\|110387_110738_-\|DUF5388-domain-containing-protein	gnl\|CDD\|375154	pfam17363, DUF5388, Family of unknown function (DUF5388). This is a family of unknown function found in Lactobacillales.	7.13772e-19
NZ_CP012291.1\|WP_062904603.1\|100263_101106_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	6.45472e-136
NZ_CP012291.1\|WP_002816285.1\|99958_100210_+\|IS3-family-transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.47634e-08
NZ_CP012291.1\|WP_062916907.1\|118709_119741_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	9.62297e-77

>NZ_CP012291.1|WP_046872463.1|110739_111540_-|AAA-family-ATPase
MGEVITFGNFKGGTGKTTNATLACLALARAGKKTLLIDFDPQANATDIYFKTAANLGHDDIKFNQTLLASIQEEDLSRSLVTLDKNIDFIPSSADFSLYPRIMEKKFKNNYKDRVTYFSKLLASLKEKYDFVVFDLPPTISLISDSALYASDWVLIILQTQEHSLQGAESFLKYIQEQVIDEYEAPSLNLLGILPVLLKNGAPVDHSTLEVAEEEFGKENMLKTLIRNMERIKRYSIRGVFLKDQFDKKIIRLYDSVAQEIVERAD
>NZ_CP012291.1|WP_046872462.1|110387_110738_-|DUF5388-domain-containing-protein
MVELLHNPNSNKSKIIPRKSVPQPQKEISISSLNESNKTKSKQIDGVTFDTTLRIDNHLKNFMKAMVILGYSSTQQNGLAQLQKTFFESLTESEQNTLTTQIQTLETGDANKVKSK
>NZ_CP012291.1|WP_062904605.1|105453_107568_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MANFYENDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGKSLTPDEFAQYRATGKLPQNNKTIEVSKDGKQAFKKGGILEKLGTNLTEQARDGLLDPVIGRENEIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSSLEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKPALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKHHHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKKLEAAKEAAVKSEDFTKAADIKKSIEETKQKIKKTDQKEKITATIDDVAQSVERLTGIPVADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPTGVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTERVRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFSNEALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLAKKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADLVDGEIVISAA
>NZ_CP012291.1|WP_062916767.1|104307_105237_+|IS30-like-element-ISLpl1-family-transposase
MSSITYSERIKIETYCELGLSNIQMGVRLNRSPSTISYELSRCQPYQAELAQTDAEYKRSRCGRKTKLSDELKQKILNHLRLSWSPGMIAHEFKLATKSIYNWLNQGRIGFSLNDLPEHGVRQRRNVDQRSKYNQSLGRSIEQRPMMINQRNRIGDFELDTVVGPRGHSKAVLLTLIDRKSRFLWAYRLKDRTTATVNEALTKFLTTFNGPVHSFTVDRGTEFSGLVSLESQYGIKTYYCHAYTPAERGSNERFNRNLRYFYPKGTRFEHISAQDLTTTLLQINQRPLKILDWQTPYQVMLTNLSKNSD
>NZ_CP012291.1|WP_081115635.1|103831_104281_-|hypothetical-protein
MVNTILKEADLFCPNSVRINFTIYLFVIFFSILLFLTVGMSEKAYAEQISGTVHNELVGTFDKSQTSNRTIEEMKKIARDDHNVTLLITNNQVTISENIGVSDGATLRVQNQEVPIKNGKFTVNTKKCSTSKYNFSDANVKTDVTVDCK
>NZ_CP012291.1|WP_081115631.1|101472_102378_+|alpha/beta-hydrolase
MKVTQAVLDDIKRTTDQWRASDEKRDAGLPTEFPDVKRYDNISYGPAGEENLLDVYTPKDVTQSVPTIIDIHGGGNVYGSKELYQHYCLDWAKHGFGVVNFNYRLAPQNIFPGALKDTALVAKWVADHGQDYHLDTNNVFIIGDSAGGTLAYQYLTAYANPKYRKALGLVSSGQLVVRGGALNSGFYFVKRPGAITPDSLMSAYFTPEMMQKYDQELHTENYVTPDFPPVFVMTANHDFLHDEGVRFDQFLLDHHLAHRFASFGTESDPREHVFQLNQRDAVAAKANQQQREFFRSLFVEK
>NZ_CP012291.1|WP_062904603.1|100263_101106_+|IS3-family-transposase
MCRILGVSRAQYYRYRSPKPSKCRAEDEDLKQWILRIFAEFKQRYGVMKIHHELNLELQPLQRRCSPRRISRLMKELDIHSITVNKWKAASASKTKVEQRPNLLKQDFSTTGLNQKWTADMTYIQTKRNGWCYLSTIMDLHSRRIIGYSFSKKMATDLVLTTLESAVKNRTITGDLIIHTDLGSQYTSDDYNQRLTELHIRHSYSRKGCPYDNAPMESFHASLKKECVYPVPVFENYETAATVLFEYVHAFYNRKRIHSSLGYQTPLQVEVATLTSQMAA
>NZ_CP012291.1|WP_002816285.1|99958_100210_+|IS3-family-transposase
MPTRYDKEFKQNIINLYKQGESAAQLAREYGIGYSTVHKWIQGQAKTQSGKSPDEIKAMEKRLASLSEENEILKKALGFLAQK
>NZ_CP012291.1|WP_062904602.1|97665_99432_+|alpha-glycosidase
MNFAAIYHRPESEMAFLDDPQTMHIRLRTAKGDIKTVQLLHGDPYSLRSLASIKPPFYITPTPMKKILSDDLYDYWQIAVTEPKKRLAYAFDITSVDGIRTVYTDHGYIQPDDHGALEDLNTYFRMPFFQEIDMFHSSEWVKNTVWYQIFPERFANGDRSNDPIGTKKWNASDHPGRQDFYGGDLQGVLDHLNHLQKLGVNGIYFNPLFKAPSNHKYDTEDYYQIDPHFGNAALFKEVVTQAHQRGIHVMLDAVFNHIGDKSLQWQDVLKNGQRSKYAGWFHVNKFPATYTPTKNFEFTPDATYDTFDYTPHMPKLNTANPAVQEYLLGIAKYWIKEFDIDAWRLDVANEIDHHFWKRFHKETTALKPDFYILGEIWHTSQAWLNGDEFSGVMNYSYTGAILDHFINHRISAEQMIDHLSNQLMKYRDQTNQMMFNVLDSHDTARIMTQARGNRDLVKETFAFTFLQPGTPSIYYGTEYGMDGDNDPDCRKPMNWVPDDDGQDMFTFFKKLVALRRNNADLIEGGMVVLKVLPTGLVEISRMGAGKVLTGIFNTTNLPIKCLSTGRLLLSQGVQDHQLMPNGFVITMK
>NZ_CP012291.1|WP_062904601.1|96319_97666_+|SLC45-family-MFS-transporter
MNRKKLNKRLPSLAFSVLMLMTFGNLGTSMAFSLQSANMGRIFQTLGADPTKLGWFFILPPLAGMVVQPLVGYFSDRTWIPKIGRRLPYLILGTIVAVIVMFLLPNSGSFGFKTSTALWFGAVTILFMDLSSNMSMQPFKMMISDMVNDEQKDQAWSWQTIWGNIGGVAADLFPFLLTWIGIKNIAAKGELPDSVKWSFYIGAAILIVSSIFTICKVDEYNPETYAKYHGLDQDANISENFFTIIKHAPKVFWTLGIVEFFSWTGFQYLWTYGAGTVAQNIWHTTNASSAAYQAAGNWFGVLSAVEVAVAIIYGLILQKLNDRIRKPAYALGMILGALGFWGLSVAPTKLWSVIAFIGIGMCWVTINSIPFTILTNALDGKHDGTYMGLFNSWICFPQVVASVCSFALYPLLGNYMPHMLVVAAVLALIGAFAVYVVKEISVERGDIE
>NZ_CP012291.1|WP_062904581.1|111869_113117_+|ISL3-family-transposase
MQMSLTNPILCLFEITDPNLIVTGISKERCSTNQRIHVVHATLSYQLLKCPHCGHKSLIKNGTHMSHLRLGTLSGGRYEMHLKRQRYQCKDCSKTCGAKTKLVNRNETFTHNIKHQVIVLARDMLTSKEIAKLCGISPSSVQRILNANIHLAYRVKHLPENLCFDEFRSCNHWMSFNCCDAVSHRRIVTLKDRLSKDIIDYFEARFSVQERAQVQSVTIDMNAEYGSFIHRLFPNAATIIDRFHIIQLAGRALDNERTQTIRTIQDKHSRIYHILKSQWRLFHLDEIKVNDSKAVYLRGINEYMTQQNAIDLALDAFPRFRSVYQTYQGILSAIHQKDANAFQSLLTNYQPTSNQMDITINTFIKNGSALLNSCRYPFSNGPIEGLNRKIKALKRNCFGFRNIDNFFIRISLIHE
>NZ_CP012291.1|WP_020923847.1|113825_114104_+|BRCT-domain-containing-protein
MLDLRDCEIAFTGRLTTMTRDQAFSLAKVFGAKPQNWVTKQTDYLVVGLIETALGEEPITKKLLTGTPTISERDFLDWCQARLAQWSRSLGG
>NZ_CP012291.1|WP_035168888.1|114284_114485_+|hypothetical-protein
MNIPRVTQLTVGDLKQLLNQYDDSTTVYVSNDTAKEVSAYEAVSVESDVLDDKPLIIISGGIVDER
>NZ_CP012291.1|WP_046872572.1|114497_114872_+|DUF536-domain-containing-protein
MLTYKELADKLGVKKDTIIYRARKPPDKSIIKKNGINYLTDSAAETISKTIQQKKQTDNTRNTNDTVLTEQLAIKDQQITKLQQLLDQQQQLTANLQNKLETTQQQLTTAETQKTKHWWQKLFS
>NZ_CP012291.1|WP_145974422.1|116418_116865_+|SHOCT-domain-containing-protein
MYVISFEEDGLLFMGINLANQFTNSDKFIPLSEIGSISYKSSKLINGRLVFNAEKLIINSKDGKTSEHLMYTMVAIASWIKKDLPNVHARIDSYPSLKESFSAKEEPSVVADTSSAADKLRELKALLDEGVITRSEFDEKKRDILSEL
>NZ_CP012291.1|WP_046872533.1|116997_117291_-|hypothetical-protein
MKDWEYSNFTKEASMFGGPAKFIATIKEEAEKAGIEKGLVIGLSAGVLVTSVSVTAYKKTKSLLAKRKQEKKLAKEAEEQLMQELHDMDENPDDTIQ
>NZ_CP012291.1|WP_062916905.1|117558_118299_-|IS3-family-transposase
MCRILGVSRAQYYRYRSPKPSKRRAEDAGLKQRILRIFAEFKQRYGVMKIHHELNLELQPLQLRCSPRRISRLMKELDSHSVTVNKWKAASASKTKVEQRPNLLKQDFSTTGLNQKWTADMTYIQTKRNGWCYLSTIMDLHSRRIIGYSFSKKMATDLVLKTLESAVKNRTITGDLIIHTDLGSQYTSDDYNQRLTELHIRHSYSRKGCPYDNAPMESFHACLKKECVYPVPVFEDYETAAAVLFE
>NZ_CP012291.1|WP_145974423.1|118352_118568_-|transposase
MINLYKQGESAAQLAREYGIGYSAVHKWIQGQAKTQSGKSPDEIKAMEKRLASLSEENEILKKALGFLAQK
>NZ_CP012291.1|WP_062916907.1|118709_119741_+|IS30-family-transposase
MQEQNTTVRKKGQHLTSFERGRIATLHSQGYSNRAIARALNVCHQTINNELCRGEIDQVKKVNGQRQYYAVYSPETAQAKYEANRAHCHRPLKLVGIADFIDYFTTHLRQDGWSPDAAVGRAKLEGLYQPEEMVSTKTLYHYIDAQLLEVRNLDLLEKTRHRAKHHHSIKHKRLAGRSIDERPKSIDQRQEFGHFELDTVVGKRNGQESVILTLIERQSRCQILRLIDGRDADSVNYKLAKICQEYGSIMKSVTADNGAEFSEVGAVLTGVANLYYAHPYRSSERGTNEAHNRMIRRDVPKGLSMDILGPHDIQAVESKLNNLPRRQTGYQTPKELFSAASAG
>NZ_CP012291.1|WP_062916923.1|120145_121099_+|LacI-family-DNA-binding-transcriptional-regulator
MITIKDIARRAGVSVSTASRALNNNSRISLKTRERIQKLAKDLDYLPNYTAKNLTRGEANVVGVIFPTVESSSPENPFYIDMLRGINQSLVARHYVLSIAIGSRVEEVLANVTAMVQQAKVKRFVLLYTDENDPVVDYLRRENLDFVVIGQPVGDLPDRYVDNDNVQAGRDATMAILQNGGVRNPLFVESEYEWQYEQNRRMGYEKAMAEVQLEPLVFRLPKRVSETAVEVFLNQHQDVDAVIATDDVGLLRFNRVWSKIRHTKKIPMMSFNKSELLALIDQDVRMVDMRPEMLGSRAVELLFTDRNVQKLIVQYEL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NC_021233	Lactobacillus plantarum subsp. plantarum P-8 plasmid LBPp1, complete sequence	29698-29716	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP042372	Lactobacillus malefermentans strain CBA3618 plasmid unnamed1, complete sequence	38622-38640	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP024414	Lactobacillus plantarum strain ATCC 8014 plasmid pLP49, complete sequence	42590-42608	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP025692	Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence	3703-3721	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP015859	Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence	6607-6625	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP015859	Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence	75408-75426	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP031186	Lactobacillus brevis strain SA-C12 plasmid pSAC12_A, complete sequence	12478-12496	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP021481	Lactobacillus brevis strain SRCM101174 plasmid pLB1174-3 sequence	12311-12329	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP035560	Lactobacillus plantarum strain SRCM103297 plasmid unnamed4	13802-13820	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP032748	Lactobacillus paraplantarum strain DSM 10667 plasmid unnamed4, complete sequence	32040-32058	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP012276	Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-1, complete sequence	25072-25090	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP031211	Lactobacillus brevis strain UCCLB521 plasmid pUCCLB521_C, complete sequence	15201-15219	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP024059	Lactobacillus plantarum strain KACC 92189 plasmid unnamed1	49761-49779	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP014884	Lactobacillus backii strain TMW 1.1991 plasmid pL11991-3, complete sequence	32488-32506	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP023491	Lactobacillus plantarum strain NCIMB 700965 plasmid unamed1, complete sequence	59305-59323	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP035028	Lactobacillus plantarum strain YW11 plasmid plsm_YW11_pC, complete sequence	6247-6265	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP035028	Lactobacillus plantarum strain YW11 plasmid plsm_YW11_pC, complete sequence	51664-51682	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP014916	Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-1, complete sequence	27774-27792	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP014624	Lactobacillus backii strain TMW 1.1988 plasmid L11988-1, complete sequence	26489-26507	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP016800	Lactobacillus brevis strain TMW 1.2112 plasmid pl12112-3, complete sequence	11368-11386	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP035023	Lactobacillus plantarum strain 13_3 plasmid plsm_LP12_3_pC	6247-6265	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP035023	Lactobacillus plantarum strain 13_3 plasmid plsm_LP12_3_pC	51665-51683	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP019752	Lactobacillus brevis strain TMW 1.2113 plasmid pl12113-2, complete sequence	772-790	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP012659	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK05, complete sequence	17127-17145	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP015339	Lactobacillus brevis strain 100D8 plasmid unnamed1, complete sequence	38260-38278	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP026506	Lactobacillus plantarum strain NCIMB700965.EF.A plasmid punamed1, complete sequence	58709-58727	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP047123	Lactobacillus hilgardii strain FLUB plasmid unnamed2	32873-32891	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP017699	Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-5, complete sequence	17389-17407	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP031176	Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_B, complete sequence	28337-28355	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP046663	Lactobacillus plantarum strain 83-18 plasmid p83-18.3, complete sequence	8190-8208	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP048922	Lactobacillus plantarum strain X7022 plasmid unnamed1, complete sequence	1204-1222	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP028263	Lactobacillus plantarum strain SRCM102737 plasmid unnamed2, complete sequence	37920-37938	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NC_020822	Lactobacillus brevis KB290 plasmid pKB290-4, complete sequence	8677-8695	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP014893	Lactobacillus backii strain TMW 1.1992 plasmid pL11992-3, complete sequence	38683-38701	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP028242	Lactobacillus plantarum strain SRCM101518 plasmid unnamed1, complete sequence	71241-71259	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP013153	Lactobacillus plantarum strain MF1298 plasmid pMF1298-3, complete sequence	38454-38472	0	1.0
NZ_CP012291_1	1.1\|111591\|19\|NZ_CP012291\|CRISPRCasFinder	111591-111609	19	NZ_CP012291	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-3, complete sequence	111591-111609	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NC_021233	Lactobacillus plantarum subsp. plantarum P-8 plasmid LBPp1, complete sequence	29754-29785	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP042372	Lactobacillus malefermentans strain CBA3618 plasmid unnamed1, complete sequence	38678-38709	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP024414	Lactobacillus plantarum strain ATCC 8014 plasmid pLP49, complete sequence	42646-42677	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP025692	Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence	3759-3790	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP015859	Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence	6663-6694	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP015859	Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence	75464-75495	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP031186	Lactobacillus brevis strain SA-C12 plasmid pSAC12_A, complete sequence	12409-12440	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP021481	Lactobacillus brevis strain SRCM101174 plasmid pLB1174-3 sequence	12242-12273	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP035560	Lactobacillus plantarum strain SRCM103297 plasmid unnamed4	13858-13889	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP032748	Lactobacillus paraplantarum strain DSM 10667 plasmid unnamed4, complete sequence	32096-32127	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP012276	Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-1, complete sequence	25120-25151	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP024059	Lactobacillus plantarum strain KACC 92189 plasmid unnamed1	49692-49723	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP014884	Lactobacillus backii strain TMW 1.1991 plasmid pL11991-3, complete sequence	32544-32575	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP023491	Lactobacillus plantarum strain NCIMB 700965 plasmid unamed1, complete sequence	59361-59392	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP035028	Lactobacillus plantarum strain YW11 plasmid plsm_YW11_pC, complete sequence	6178-6209	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP035028	Lactobacillus plantarum strain YW11 plasmid plsm_YW11_pC, complete sequence	51595-51626	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP014916	Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-1, complete sequence	27830-27861	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP014624	Lactobacillus backii strain TMW 1.1988 plasmid L11988-1, complete sequence	26420-26451	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP016800	Lactobacillus brevis strain TMW 1.2112 plasmid pl12112-3, complete sequence	11424-11455	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP035023	Lactobacillus plantarum strain 13_3 plasmid plsm_LP12_3_pC	6178-6209	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP035023	Lactobacillus plantarum strain 13_3 plasmid plsm_LP12_3_pC	51596-51627	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP019752	Lactobacillus brevis strain TMW 1.2113 plasmid pl12113-2, complete sequence	828-859	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP012659	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK05, complete sequence	17058-17089	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP015339	Lactobacillus brevis strain 100D8 plasmid unnamed1, complete sequence	38316-38347	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP026506	Lactobacillus plantarum strain NCIMB700965.EF.A plasmid punamed1, complete sequence	58765-58796	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP047123	Lactobacillus hilgardii strain FLUB plasmid unnamed2	32921-32952	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP017699	Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-5, complete sequence	17320-17351	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP031176	Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_B, complete sequence	28268-28299	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP046663	Lactobacillus plantarum strain 83-18 plasmid p83-18.3, complete sequence	8121-8152	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP048922	Lactobacillus plantarum strain X7022 plasmid unnamed1, complete sequence	1260-1291	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP028263	Lactobacillus plantarum strain SRCM102737 plasmid unnamed2, complete sequence	37976-38007	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NC_020822	Lactobacillus brevis KB290 plasmid pKB290-4, complete sequence	8733-8764	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP014893	Lactobacillus backii strain TMW 1.1992 plasmid pL11992-3, complete sequence	38739-38770	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP028242	Lactobacillus plantarum strain SRCM101518 plasmid unnamed1, complete sequence	71297-71328	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP013153	Lactobacillus plantarum strain MF1298 plasmid pMF1298-3, complete sequence	38510-38541	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP012291	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-3, complete sequence	111639-111670	0	1.0
NZ_CP012291_1	1.2\|111639\|32\|NZ_CP012291\|CRISPRCasFinder	111639-111670	32	NZ_CP031211	Lactobacillus brevis strain UCCLB521 plasmid pUCCLB521_C, complete sequence	15257-15288	1	0.969

1. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NC_021233 (Lactobacillus plantarum subsp. plantarum P-8 plasmid LBPp1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

2. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP042372 (Lactobacillus malefermentans strain CBA3618 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

3. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP024414 (Lactobacillus plantarum strain ATCC 8014 plasmid pLP49, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

4. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP025692 (Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

5. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP015859 (Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

6. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP015859 (Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

7. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP031186 (Lactobacillus brevis strain SA-C12 plasmid pSAC12_A, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

8. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP021481 (Lactobacillus brevis strain SRCM101174 plasmid pLB1174-3 sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

9. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035560 (Lactobacillus plantarum strain SRCM103297 plasmid unnamed4) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

10. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP032748 (Lactobacillus paraplantarum strain DSM 10667 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

11. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP012276 (Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

12. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP031211 (Lactobacillus brevis strain UCCLB521 plasmid pUCCLB521_C, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

13. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP024059 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed1) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

14. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP014884 (Lactobacillus backii strain TMW 1.1991 plasmid pL11991-3, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

15. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP023491 (Lactobacillus plantarum strain NCIMB 700965 plasmid unamed1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

16. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035028 (Lactobacillus plantarum strain YW11 plasmid plsm_YW11_pC, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

17. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035028 (Lactobacillus plantarum strain YW11 plasmid plsm_YW11_pC, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

18. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP014916 (Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

19. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP014624 (Lactobacillus backii strain TMW 1.1988 plasmid L11988-1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

20. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP016800 (Lactobacillus brevis strain TMW 1.2112 plasmid pl12112-3, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

21. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035023 (Lactobacillus plantarum strain 13_3 plasmid plsm_LP12_3_pC) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

22. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035023 (Lactobacillus plantarum strain 13_3 plasmid plsm_LP12_3_pC) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

23. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP019752 (Lactobacillus brevis strain TMW 1.2113 plasmid pl12113-2, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

24. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP012659 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK05, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

25. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP015339 (Lactobacillus brevis strain 100D8 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

26. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP026506 (Lactobacillus plantarum strain NCIMB700965.EF.A plasmid punamed1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

27. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP047123 (Lactobacillus hilgardii strain FLUB plasmid unnamed2) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

28. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP017699 (Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-5, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

29. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP031176 (Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_B, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

30. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP046663 (Lactobacillus plantarum strain 83-18 plasmid p83-18.3, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

31. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP048922 (Lactobacillus plantarum strain X7022 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

32. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP028263 (Lactobacillus plantarum strain SRCM102737 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

33. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NC_020822 (Lactobacillus brevis KB290 plasmid pKB290-4, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

34. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP014893 (Lactobacillus backii strain TMW 1.1992 plasmid pL11992-3, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

35. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP028242 (Lactobacillus plantarum strain SRCM101518 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

36. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP013153 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-3, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

37. spacer 1.1|111591|19|NZ_CP012291|CRISPRCasFinder matches to NZ_CP012291 (Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-3, complete sequence) position: , mismatch: 0, identity: 1.0

aggatgataacatacaaag	CRISPR spacer
aggatgataacatacaaag	Protospacer
*******************

38. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NC_021233 (Lactobacillus plantarum subsp. plantarum P-8 plasmid LBPp1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

39. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP042372 (Lactobacillus malefermentans strain CBA3618 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

40. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP024414 (Lactobacillus plantarum strain ATCC 8014 plasmid pLP49, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

41. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP025692 (Lactobacillus plantarum strain IRG1 plasmid pIRG102, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

42. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP015859 (Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

43. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP015859 (Lactobacillus plantarum strain LZ227 plasmid LZ227p4, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

44. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP031186 (Lactobacillus brevis strain SA-C12 plasmid pSAC12_A, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

45. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP021481 (Lactobacillus brevis strain SRCM101174 plasmid pLB1174-3 sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

46. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035560 (Lactobacillus plantarum strain SRCM103297 plasmid unnamed4) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

47. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP032748 (Lactobacillus paraplantarum strain DSM 10667 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

48. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP012276 (Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

49. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP024059 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed1) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

50. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP014884 (Lactobacillus backii strain TMW 1.1991 plasmid pL11991-3, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

51. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP023491 (Lactobacillus plantarum strain NCIMB 700965 plasmid unamed1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

52. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035028 (Lactobacillus plantarum strain YW11 plasmid plsm_YW11_pC, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

53. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035028 (Lactobacillus plantarum strain YW11 plasmid plsm_YW11_pC, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

54. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP014916 (Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

55. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP014624 (Lactobacillus backii strain TMW 1.1988 plasmid L11988-1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

56. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP016800 (Lactobacillus brevis strain TMW 1.2112 plasmid pl12112-3, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

57. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035023 (Lactobacillus plantarum strain 13_3 plasmid plsm_LP12_3_pC) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

58. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP035023 (Lactobacillus plantarum strain 13_3 plasmid plsm_LP12_3_pC) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

59. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP019752 (Lactobacillus brevis strain TMW 1.2113 plasmid pl12113-2, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

60. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP012659 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK05, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

61. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP015339 (Lactobacillus brevis strain 100D8 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

62. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP026506 (Lactobacillus plantarum strain NCIMB700965.EF.A plasmid punamed1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

63. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP047123 (Lactobacillus hilgardii strain FLUB plasmid unnamed2) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

64. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP017699 (Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 plasmid pLDW-5, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

65. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP031176 (Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_B, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

66. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP046663 (Lactobacillus plantarum strain 83-18 plasmid p83-18.3, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

67. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP048922 (Lactobacillus plantarum strain X7022 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

68. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP028263 (Lactobacillus plantarum strain SRCM102737 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

69. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NC_020822 (Lactobacillus brevis KB290 plasmid pKB290-4, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

70. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP014893 (Lactobacillus backii strain TMW 1.1992 plasmid pL11992-3, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

71. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP028242 (Lactobacillus plantarum strain SRCM101518 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

72. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP013153 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-3, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

73. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP012291 (Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-3, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattgactgcaagt	Protospacer
********************************

74. spacer 1.2|111639|32|NZ_CP012291|CRISPRCasFinder matches to NZ_CP031211 (Lactobacillus brevis strain UCCLB521 plasmid pUCCLB521_C, complete sequence) position: , mismatch: 1, identity: 0.969

caaaagccgttaaattaagattgactgcaagt	CRISPR spacer
caaaagccgttaaattaagattaactgcaagt	Protospacer
**********************.*********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7989 : 65080

Lactobacillus_phage(25.0%)

terminase,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_056986395.1\|7989_8727_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	7.2e-30	39.7
WP_056986393.1\|9051_9933_+	DUF1003 domain-containing protein	NA	NA	NA	NA
WP_046871959.1\|10091_10415_+	multidrug efflux SMR transporter	E5E3Y9	Acinetobacter_phage	5.4e-06	31.1
WP_046871958.1\|10505_10949_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_017260570.1\|11410_11749_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_056986391.1\|11748_12165_+	cupin domain-containing protein	NA	NA	NA	NA
WP_046041507.1\|12792_14157_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	5.3e-10	22.9
WP_062916868.1\|15964_17209_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	7.1e-46	31.9
WP_020923840.1\|17378_17657_-	hypothetical protein	NA	NA	NA	NA
WP_062916870.1\|17679_17889_-	hypothetical protein	NA	NA	NA	NA
WP_062916872.1\|18159_20220_+	MobA/MobL family protein	NA	NA	NA	NA
WP_081213106.1\|20232_20418_+	hypothetical protein	NA	NA	NA	NA
WP_062916875.1\|20481_21510_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.4e-36	32.2
WP_062916921.1\|21639_22749_+	family 20 glycosylhydrolase	NA	NA	NA	NA
WP_056986474.1\|24298_25189_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_052694451.1\|25793_26408_+	HNH endonuclease	A8YQN4	Lactobacillus_phage	1.6e-11	28.7
WP_062916877.1\|26606_27065_+\|terminase	phage terminase small subunit P27 family	E9LUP8	Lactobacillus_phage	5.8e-78	93.4
WP_062916878.1\|27096_27447_+	hypothetical protein	E9LUP9	Lactobacillus_phage	1.9e-17	82.7
WP_062916881.1\|27998_29237_+	ATP-binding protein	NA	NA	NA	NA
WP_003589711.1\|29239_30109_+	hypothetical protein	NA	NA	NA	NA
WP_003589709.1\|30262_30622_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2I6TCA4	Escherichia_phage	3.5e-06	33.7
WP_003589707.1\|30623_30902_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_062916883.1\|31022_33788_+	class I SAM-dependent DNA methyltransferase	Q6NE04	Leptospira_phage	1.2e-157	37.3
WP_056988651.1\|33838_34225_-	hypothetical protein	NA	NA	NA	NA
WP_062904599.1\|34427_35015_+	recombinase family protein	M4QQC6	Vibrio_phage	1.0e-18	42.3
WP_081115629.1\|35278_35560_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_046872291.1\|37256_38624_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_062904601.1\|38762_40109_+	SLC45 family MFS transporter	NA	NA	NA	NA
WP_062904602.1\|40108_41875_+	alpha-glycosidase	NA	NA	NA	NA
WP_002816285.1\|42401_42653_+\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	9.2e-38	96.4
WP_062904603.1\|42706_43549_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	5.9e-153	96.4
WP_081115631.1\|43915_44821_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_081115635.1\|46273_46723_-	hypothetical protein	NA	NA	NA	NA
WP_062916767.1\|46749_47679_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW47	unidentified_phage	3.0e-25	34.4
WP_062904605.1\|47895_50010_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	2.2e-119	38.9
WP_062916885.1\|51115_52045_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	6.3e-23	29.2
WP_062916887.1\|52213_52738_+	hypothetical protein	NA	NA	NA	NA
WP_062916889.1\|52762_53611_+	hypothetical protein	NA	NA	NA	NA
WP_162259330.1\|53921_54095_-	hypothetical protein	NA	NA	NA	NA
WP_057879148.1\|54161_54497_-	DUF5388 domain-containing protein	NA	NA	NA	NA
WP_057879149.1\|54489_55299_-	AAA family ATPase	F0PIG8	Enterococcus_phage	4.8e-51	43.1
WP_020923847.1\|56239_56518_+	BRCT domain-containing protein	NA	NA	NA	NA
WP_054762789.1\|57634_57916_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_082918593.1\|57905_58310_+	hypothetical protein	NA	NA	NA	NA
WP_056986624.1\|58412_59684_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.7e-47	32.3
WP_056986587.1\|59876_60557_-	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_056986588.1\|60561_60990_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_056986589.1\|61302_62979_+	acetolactate synthase AlsS	E5EQ70	Micromonas_sp._RCC1109_virus	2.1e-37	24.1
WP_056986590.1\|62998_63709_+	acetolactate decarboxylase	NA	NA	NA	NA
WP_062916891.1\|63808_65080_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.9e-47	32.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage