CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP012295	Pediococcus damnosus strain TMW 2.1536 plasmid pL21536-1, complete sequence	0 crisprs	NA	0	0
NZ_CP012294	Pediococcus damnosus strain TMW 2.1536 chromosome, complete genome	4 crisprs	RT,cas3,csa3,DEDDh,WYL,cas9,cas1,cas2,csn2,DinG	17	7
NZ_CP012296	Pediococcus damnosus strain TMW 2.1536 plasmid pL21536-2, complete sequence	0 crisprs	cas2	0	5

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012294_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012294_1

542851-543001

Orphan

Consensus_repeat	Method
TGAGGACGGCTCGACAAAGCAGAAGTCAAAATATAACTATCCTTCCCGCGGGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012294_1

>merge|NZ_CP012294|1|542851-543001|CRISPRCasFinder
TGAGGACGGCTCGACAAAGCAGAAGTCAAAATATAACTATCCTTCCCGCGGGATTGCGATTCCGTTTACTTGTGGGCCCATCTCTTTTCTGCTTTTTTGAGGACGGCTCGACAAAGCAAAAGTCAAAATATAACTATCCTTCCCGCGGGAT

>NZ_CP012294|1|1|542851-543001|CRISPRCasFinder
TGAGGACGGCTCGACAAAGCAGAAGTCAAAATATAACTATCCTTCCCGCGGGAT	TGCGATTCCGTTTACTTGTGGGCCCATCTCTTTTCTGCTTTTT
TGAGGACGGCTCGACAAAGCAAAAGTCAAAATATAACTATCCTTCCCGCGGGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012294.1\|WP_046872436.1\|548374_548785_-\|transcriptional-regulator-Spx	unknown	unknown	gnl\|CDD\|179316
NZ_CP012294.1\|WP_062913150.1\|544575_545436_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
NZ_CP012294.1\|WP_046872429.1\|541396_542782_+\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP012294.1\|WP_062913148.1\|535519_536593_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP012294.1\|WP_172793946.1\|543055_543847_-\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|223635
NZ_CP012294.1\|WP_046870642.1\|550353_551124_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|379135
NZ_CP012294.1\|WP_046872433.1\|545772_546429_+\|membrane-protein	unknown	unknown	gnl\|CDD\|225239
NZ_CP012294.1\|WP_046872437.1\|549259_549517_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_062913149.1\|544033_544513_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|179443
NZ_CP012294.1\|WP_046872426.1\|537281_537710_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|107228
NZ_CP012294.1\|WP_046870641.1\|549550_550342_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|379135
NZ_CP012294.1\|WP_046872434.1\|546514_547306_+\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|379135
NZ_CP012294.1\|WP_046872435.1\|547336_548281_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223999
NZ_CP012294.1\|WP_056986457.1\|537953_538337_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_145930480.1\|534188_535166_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381318
NZ_CP012294.1\|WP_046872428.1\|538416_541149_-\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NZ_CP012294.1\|WP_046872421.1\|533106_533442_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_046872420.1\|532418_532955_-\|DUF1836-domain-containing-protein	unknown	unknown	gnl\|CDD\|378076
NZ_CP012294.1\|WP_052694569.1\|536690_537221_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP012294.1\|WP_046872422.1\|533451_534018_+\|DUF5067-domain-containing-protein	unknown	unknown	gnl\|CDD\|374759

Protein	Function_ID	Function_description	E-value
NZ_CP012294.1\|WP_046872429.1\|541396_542782_+\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	3.54247e-103
NZ_CP012294.1\|WP_062913148.1\|535519_536593_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.43394e-77
NZ_CP012294.1\|WP_172793946.1\|543055_543847_-\|HAD-family-phosphatase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	7.43948e-54
NZ_CP012294.1\|WP_046870642.1\|550353_551124_-\|tyrosine-protein-phosphatase	gnl\|CDD\|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	7.15028e-71
NZ_CP012294.1\|WP_062913149.1\|544033_544513_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|179443	PRK02551, PRK02551, flavoprotein NrdI; Provisional.	1.43886e-83
NZ_CP012294.1\|WP_046872426.1\|537281_537710_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|107228	cd06471, ACD_LpsHSP_like, Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.	2.14064e-44
NZ_CP012294.1\|WP_046870641.1\|549550_550342_-\|tyrosine-protein-phosphatase	gnl\|CDD\|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	6.24034e-76
NZ_CP012294.1\|WP_046872434.1\|546514_547306_+\|tyrosine-protein-phosphatase	gnl\|CDD\|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	1.33281e-84
NZ_CP012294.1\|WP_046872428.1\|538416_541149_-\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP012294.1\|WP_046872435.1\|547336_548281_+\|alpha/beta-hydrolase	gnl\|CDD\|223999	COG1073, COG1073, Hydrolases of the alpha/beta superfamily [General function prediction only].	2.08504e-18
NZ_CP012294.1\|WP_046872436.1\|548374_548785_-\|transcriptional-regulator-Spx	gnl\|CDD\|179316	PRK01655, spxA, transcriptional regulator Spx; Reviewed.	7.31277e-38
NZ_CP012294.1\|WP_145930480.1\|534188_535166_-\|aldo/keto-reductase	gnl\|CDD\|381318	cd19092, AKR_BsYcsN_EcYdhF-like, Bacillus subtilis YcsN, Escherichia coli YdhF and similar proteins. Bacillus subtilis YcsN and Escherichia coli YdhF are prototypes of this family. They are uncharacterized aldo/keto reductase family oxidoreductases.	1.54125e-125
NZ_CP012294.1\|WP_046872422.1\|533451_534018_+\|DUF5067-domain-containing-protein	gnl\|CDD\|374759	pfam16729, DUF5067, Domain of unknown function (DUF5067).	4.83698e-11
NZ_CP012294.1\|WP_046872433.1\|545772_546429_+\|membrane-protein	gnl\|CDD\|225239	COG2364, COG2364, Predicted membrane protein [Function unknown].	4.9437e-09
NZ_CP012294.1\|WP_046872420.1\|532418_532955_-\|DUF1836-domain-containing-protein	gnl\|CDD\|378076	pfam08876, DUF1836, Domain of unknown function (DUF1836). This family of proteins are functionally uncharacterized.	9.20891e-35
NZ_CP012294.1\|WP_052694569.1\|536690_537221_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.29983e-16
NZ_CP012294.1\|WP_062913150.1\|544575_545436_-\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	1.36315e-128

>NZ_CP012294.1|WP_046872429.1|541396_542782_+|HlyC/CorC-family-transporter
MDSGQIISDTIIILITFIMAYFFVAAEFALVESRLSALEEAKETAVGGRLKKINRAIHMVSNLNEYLSTTQVGTSVCGIILGWIGESYVEYFIIKFFGSTHLINQASLHAIGAIIGVLLLTYLEVVITEIVPKNISIDIPLKVLMRLVNPLHWFHTIFYPFVWLLNTSANGIVKLMGMEPAEENNEVLSQAEILSLSKNSVTGGELDQNDYVYMQRAFDFNDKVAKDIMIDRTQLVVLNVDVTVDEALRVYLQKRFSRFPVVANNDKDKILGYVYNYDLVRQSRVDGKVKVSKLLRNIITVPETVLIQDVLQRMLKKQTPISVVVDEYGGTSGIITDKDIYEEVFGTISDEVDDVSGDYIHKESDGSYRVSGKTTMYDFERYFGIDVPGFEGEDVVTIGGYVIDHHPNIQVHDQVRIDRYNFEVLDNENAHIDWFHVTSISDNEFKKLKEDAETKRLNANG
>NZ_CP012294.1|WP_046872428.1|538416_541149_-|HAD-IC-family-P-type-ATPase
MTKGSASDSTDYGGEIEKSKPPHAFITQTTDQLLAQDHISLDQGLTSEKAQERLEQDGPNSLVQKKQSKWVRFFKQFNNSITYILIVAAVATFILREYSDSIVIGLVVIVNALIGYFQESKASDAIDNIKQMLQVSATVIRDGKRDDIEAENLVVGDLVFLEAGDNVPADLRILTADNLKIQESSLTGETDSVLKNDEPLTDPKTPLGDRLNMAYASTAVTNGSGLGIVTATGANSEIGKINASMESVKTKTTPLMQEINGLGKYISYAIVAVAVLLAIYGLITRVYSVSALMVAVITMVVGSLPEGLPASTSVVLAMGVQKMTKQNAIVKTLPAVETLGSVDVINTDKTGTLTKNEMTIDTLITQNGRYEVTGTGYTPTGHITMNGQPISVGHDEDLDRLMVAGHEANDTRLIEEDGKWEINGEPTDGAFLTLYHKVFEKNEPDLVEIDKIPFDSEYRYIAKLDEDSDGQRVILVKGSPDKIFTMAKQADSSFDIPDWTNRVSQLARDGERVVALGYRKVSNDVHELTPEIMAEGVHFLGIAGIIDPPREETIVALKEMREAGIKVKMITGDHPETASAIAKKLGLDGNIAAITGAEIDELSDEKLKEVIQDYNVFARTTPMNKLRIVEAYQANGLVTAMTGDGVNDAPALKKADIGIAMGIKGTDVAKEAADMVLADDNFATLTTAIKEGRHVYDNIKKTIRFLLPTSFAEGLIVLISIMFQQELPLVPTQLLWINMVSAVTIQFAFLFEPAEEGIMKRMPRKSNQSFLNRKDVWQIVYVAILIAGLGIGAFNWLTMQGFSSTVASTVTLNVIVFGKIFYLFNIRTPKPALSKDVLRNKMAFVIIGILLILQAGITYLPFMQEIFSTASLDASLWIIPVIAGIIVLIVTEIDKAFGLRHRLHLATSRN
>NZ_CP012294.1|WP_056986457.1|537953_538337_-|hypothetical-protein
MAKDDKVKVETDAEQIAKIDFDKEDVKQAADMIEEKGFVTRNDFPDLKDRLWSEGFYEKIEDEFHQRDNENPYIFFERFDFVGGAIESIIFDMDQVKTREKALHVLGDALDLKVQDKPNETHKMVTY
>NZ_CP012294.1|WP_046872426.1|537281_537710_-|Hsp20/alpha-crystallin-family-protein
MANELRNTDFDDFAPFDFYDNFGKNFFKSMTQGSSMKTDIRENEKDYEVSAELPGLKKENISLNYDNDTLTIEGKHNVNKEKKDEKGNLIRQERSFSNTSRQFYLPDIDRDKISASYDGGVLKITLPKSESKLESGKQIPIN
>NZ_CP012294.1|WP_052694569.1|536690_537221_+|GNAT-family-N-acetyltransferase
MKNLQTKNYELHFPVQSDVDILFRYRSNIEIAHSEGRIPDKSRQETAKFLTQLLSKIDAGIVNYWLISDHTKNHLGGISIWGFNQEKTEAEVGYDILPKFQGKGVISEVFPEIEQYAFTVLKLQKLSVYTSKIDILSQHILRKNHYRLIEHWIEKNLKGEPTDMFHFAKTIEEYQK
>NZ_CP012294.1|WP_062913148.1|535519_536593_+|IS30-family-transposase
MKEVFVLAQEQLTISHLKGHHLAQIERGKIAGLLAAGKSARQIAAEIGVCHQTINNELKRGCIQQVKKVNGKEQYFNVYAPDTAQIHYQTNRQRCHRPLNFKSITNFLAYFDDHFHQDHWSPDAAVGFAHKHRLFKRTEMVCTKTLYNYIDAQLLEIRNLDLLEKTKRRTKHHWSHKHRRLIGKSIEERPECVDKRSEFGHFEIDTVVGKRSGHECVLLTFTERKTRFDFIRLIEGKDADSVAYAIKGICAEFGDLIKSVTADNGTEFTALEEAFTGVADIYYAHPYSSSERGTNETHNRMIRRYLPKGYSLDTVSPKTVAIVEDRLNQLPRRILKYQAPEKAFQIEAARARRAHIA
>NZ_CP012294.1|WP_145930480.1|534188_535166_-|aldo/keto-reductase
MVINLFIGVIFLKQITIGGKKVSNVALGIMRMDALDTDAATKVIETAVDNGVNFIDTADIYGGGKSDLVFQKVLDKSSVSRDDLWIQSKVGIRNSNDDGSGKPYGNRYDFSKQHIIDAVNHELQSLKLDYLDSVLLHRPDPLMELNEVAEAFDELQTAGKVRHFGVSNFNPMQFDMLQGAVSQKLMFNQLQFGIMHSNMIDFGMHTNMQDAHSIDHDGQFIEYSRIHDIVIQAWSPYQWGNFNGPFIDNPKFPELNKKMQALADQYGVTKNAIATAWILRHPAKFQVLVGSMNPQHIKESLAGSDVEMTGQEWYDIYYAAGNDMP
>NZ_CP012294.1|WP_046872422.1|533451_534018_+|DUF5067-domain-containing-protein
MKSFKKVFSILMIGLVATSLTACSSGNTSKSSQQSSSSEKKVSSAKKAVKKTATLSDQTFKTPQGTFLITENHVTASATKNKQVLILKYTFTNTSKSQLVPSDYWYKYVKATQIVNGSTKTLEQGSLPFSTAATTDDNLENSSVSEIKPNHHINAEGSWQLDKNGAPVKVSFYDTHKQLVGTRQYDTN
>NZ_CP012294.1|WP_046872421.1|533106_533442_+|hypothetical-protein
MFELTKKRRVSDEVKEIIPQPVIDGLWKTLKQMQADDLVVSPVIAFVFSDDYTEDTIYVMGLQNSGDVAKEYDLAYSGKKDFLGNGTIVIVKDKPKTISMSISAVNNQTKE
>NZ_CP012294.1|WP_046872420.1|532418_532955_-|DUF1836-domain-containing-protein
MNELETYNRWLKTVREVKLPHWDELPNFDLYMDQVVALLSGYTGPLGMDPVTPTMINNYVKQKAVVAPTKKKYQVMQVADILLITLLKQAYPINVIRSGIDRITATDYPKQAYDRFIDIVNQKIARIGLEHTTTMAKNLAEQLMQVTSNMIVDQVQTSELIRLLQRSEEHTPTTLNKK
>NZ_CP012294.1|WP_172793946.1|543055_543847_-|HAD-family-phosphatase
MDIDGTLISHNQNVSLMTKKVIEQLQQKGFIFYIATGRMLSLAQVIQKRINPKVEIIASNGSVYQKGHHLHQDHLGWKAISTVYDVTMELGLSTNFFSTDRTFYTKNKPWDLSRLARMRVMQDGAGKFEDVHDRDHLNEVSDQIINGIVIAQGQLDKLAIARKKLLEADVLNVSSSSSDNIELIPKRIDKASAVRAITNQYGIPVDHTIAFGNDKNDLGMLKAVGTGVAMGNSADEIKTQADVVTETSEDDGLPKYLKRRFLD
>NZ_CP012294.1|WP_062913149.1|544033_544513_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MSIINILYISIAGNTRSFTQDLQDYAKKQHSKDATNPLITLKEISEETDFETERHPYFAFVPTYLDGGNGVDNGVKELMTNVLGEYIAYKNNRKLCLGVIGSGNRNFGLQYCLTAKRYARDYGFDYLDNYELRGNSTDCKRIYETLKKNNVLKKAPEEV
>NZ_CP012294.1|WP_062913150.1|544575_545436_-|aldo/keto-reductase
MAKLTKLTDTYELNNGTKIPIVGFGTWQTPDGDVAEKSVEEALAAGYRHIDTAFAYGNEQSVGKGIKDSGVARDQLWVTSKLDGKDHGYENTKRAVDKSLTNLGLDYLDMFLIHWLNPIAYRDTWEQTNADTWRAMEEAQKAGKIRAIGVSNFRPKHLDALLKTATVVPQVNQIFLNPSDLQPEVVKYDDDHNILSEAYSPLGTGKIFGVSELKTMSEKYHKTVAQVVLRWSLQHGFLPLPKSVHNERIIENTKLFDFEIDDADMKKIDGLRGLAGLATDPDTITW
>NZ_CP012294.1|WP_046872433.1|545772_546429_+|membrane-protein
MDKHADFKKRLFFFVISIILNSFSNALTVASHCGSALWTASSVNLSSWLNFPLSNVLFVEGLAVILANALLLQHFDWHRMLGNLVFMIPFSYLVGTISTNLDAHGFLTLPLWIRILADALGIVGIGIAVSIYQRANIVLHPNDDLTYIVRFRFMHGRAAKAQWISYIPAISIILLTFIMTHQIHAVGLGTVLAFILQGAVTGWADQHVFTTLKHHLNV
>NZ_CP012294.1|WP_046872434.1|546514_547306_+|tyrosine-protein-phosphatase
MVRSRILQLQKGGNFRELGGYETIAGKTIKWHKIIRSGKLADLTDADIAYLNDYGLKYDVDFRSPEEKATSPDRIPDQAKYLFIPVFSTDETQNSKQTERLQRKMDTDPTTGRLQMQHAYKDIITNPHSQKAYRSFFDVLLENDGEKSTLLFHCTAGKDRTGMGAVFFLNALGVNEDTIKADYLLTNKVIQQQQIMLTKTLKLQGASSAFIQSMRDLQSVQISFYNTAMDQIEKTSGDMAAYLHEYLHLSDSDIQDLRHIYLE
>NZ_CP012294.1|WP_046872435.1|547336_548281_+|alpha/beta-hydrolase
MKRKNLIGFGLVAPLALGITGITAASARLYDYAFRRVDYVPETSADKQKYADEYYNYVNWFHNIPTHHWTLHADDLENRVEATFIPAAKLDSKKTVIIAHGYKGNGETMSNYAKMFYDMGYNVLLPDDRAHGRSSGDYINFGWIDRLDFVDWANSVVSRIGADSQIIMFGVSMGGATIQMTSGENLPPQVKLMISDCGYSSLRDELSYLLKEQFNLPSKIFVPLINAINHHRMGFSIDDVSSIRQLRKNTRPFLFIHGEKDIYVPTYMVDESFEACPDPKEIWIVPNASHAESFWINPQAYQTKIQQFIDKYSK
>NZ_CP012294.1|WP_046872436.1|548374_548785_-|transcriptional-regulator-Spx
MDKITVLWGPSCGSARRACHWLDTQELTYDKVNVVSTAITLDTLKKVLSLTEYGAEEIISERSKIFKKFGREYIDSLTISELHRLLVNYPSLIKKPIIFTHNKLQVGFNEDEIRSFIPRETRRVSFAQMLNILHDA
>NZ_CP012294.1|WP_046872437.1|549259_549517_+|hypothetical-protein
MRTKYWSDFILAIIVIIACVVGWFTGYFQNGSNYSSIEKTLILILAFSVLFRLRMDMKGANRWEAVSAAFLGVAFLLAVVLLAFL
>NZ_CP012294.1|WP_046870641.1|549550_550342_-|tyrosine-protein-phosphatase
MEKQRVLPIKSGLNFRELGGYSTKDGKTIKWQKLLRSGYLSVLTKEDKHYLSDYGLRYDVDLRSDYEISRNPDPHIPEMVQVTASVYPFTTQQPSSIKRWLKHLFHKETHEPSMLSDPYQLMVLDNHAQTAFKKLFQVLLKNDQPDESVVFHCSAGKDRTGIAAFLVLSALGVPQETIENDYLLSNQVLFGKMPSLKSATATKNTALDRMNQARNVNLQSLHLAEQAIETSYQGITNYLHEAMNLSDEDLNQLKELYTEQKKV
>NZ_CP012294.1|WP_046870642.1|550353_551124_-|tyrosine-protein-phosphatase
MKKERILNVEGSVNFRELGGYSTKDGKSIKWQKLLRSGDLSRLTDEAVQNLNDYGLHYDIDLRSPSEAGWLQDRLPNDVIYRSYPVYPIAKSETSDLPELPNDSTTSDYSHPYALMIMNPQSQLAFRMMFQDMLANSDSKKSLLFHCAAGKDRTGVAGFLILTALGVDYPLIKQDYILTNVVYSTMDQDSLRKQLKNDKAENFVNKMNSVFQVQGDTLDIARQAILDNYGDYETYFKQAMKLSKADLDDLKAIYLE

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Crispr_ID: NZ_CP012294_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012294_2

1237641-1239921

TypeII

Consensus_repeat	Method
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	PILER-CR
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CRISPRCasFinder
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CRT

34 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP012294_2

>merge|NZ_CP012294|2|1237641-1239921|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCAGGTATCGTTTGTAATCCTACGAGTGCAATGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGTGATACCAGTGCCGTTTAACGCTGACATCGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCATAAAACATGATAAAGACGTTCAGCATGAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTATTATATGCAGATCCTAATGTTGAACTAAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCACTGATTAGTTTGGTCTCACAATCCAAGCGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCACGCAAGACCAAATTGATTCTGGCCCAGCAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCATGGACGTTCATGTATGGCTCATTCTCAAAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGCCCGTTTGGGTTTGGCCTTGAACATAATCGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTGTATTACAGGGCTTACATTGCCTACGCGGGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCAAAAGTTTGTGCTGCCAATGGCAGGAACGTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCATTAACAATCGCAAACTCACCATTTCCTTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGTTTGTCCGAACCGTGCGTCATGCACATCTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTACTCAATCGCAAATTGATTCCGCACCAGAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTGTTAGGCCTTCCACAGTAAAGCTAATTTTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCATTCGACTATCCCGGATTGATTGGAGATTCGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCTCGGTACGCAATAACCTTGCCGCCACGTCGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCACCCTTCGATTACTAACCCGCTTAATCTGAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTATGATGATTGCGTGCAGTAGGTGGTATACGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCAAAACGTTGATTGATAACGGTGTAGCAGATGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGTGGTAAGACTGTTTACAGTCCCTCGATAAGTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTCATCTCCTCCGATTGCATCTGTATCTAGTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTGCCGACATTGCCGAGACCCCAACCAGCTTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTTAGCTTATGCCAACATTGGTGGTAATGATGTTTTAGAAGAGTGTCGAATCAATATAGTTGAGAGCTTCGCTTTCTGTTGAATAGTAATATGTGTTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGCCATTGGTGTCTAATGACTGTGGTGCTGTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCGTGTACATGATGTGGTCGTCCCCAATGTTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCTAGATACAGGTAATCTGTGGGTATTGTGTGGTTTTAGAAGAGTGTCGAATCAATATAGTTAAAAGCTTCACCTACAATTAATGTATTACCCTTTAAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTAATAACGGAGCGTTAAAGGCTTGGAGTTAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCGGGGTCGCTTCCACATATCCTGTGGTCCAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCCGTTGGTCCGACAACTTCCGCAGCTCTTTGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCCCGGTCGTCGTCGGTTAAGTACCACTCATGGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCGTGTGGCGTTGGCTAACGTTGTTGAGGGCAGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGCTAATGTAAAAAAGCTTGACTGTATACACATGTTTTAGAAGAGTGTCGAATCAATATAGTTAAGGAA

>NZ_CP012294|2|1|1237641-1239855|PILER-CR
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AGGTATCGTTTGTAATCCTACGAGTGCAAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGATACCAGTGCCGTTTAACGCTGACATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATAAAACATGATAAAGACGTTCAGCATGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATTATATGCAGATCCTAATGTTGAACTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTGATTAGTTTGGTCTCACAATCCAAGC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACGCAAGACCAAATTGATTCTGGCCCAGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATGGACGTTCATGTATGGCTCATTCTCAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCCGTTTGGGTTTGGCCTTGAACATAATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTATTACAGGGCTTACATTGCCTACGCGG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAAGTTTGTGCTGCCAATGGCAGGAACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATTAACAATCGCAAACTCACCATTTCCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTTTGTCCGAACCGTGCGTCATGCACATCT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TACTCAATCGCAAATTGATTCCGCACCAGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTTAGGCCTTCCACAGTAAAGCTAATTTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATTCGACTATCCCGGATTGATTGGAGATTC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTCGGTACGCAATAACCTTGCCGCCACGTC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACCCTTCGATTACTAACCCGCTTAATCTGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATGATGATTGCGTGCAGTAGGTGGTATAC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAACGTTGATTGATAACGGTGTAGCAGAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGT	GGTAAGACTGTTTACAGTCCCTCGATAAGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TCATCTCCTCCGATTGCATCTGTATCTAGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGCCGACATTGCCGAGACCCCAACCAGCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TTAGCTTATGCCAACATTGGTGGTAATGAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTGAGAGC	TTCGCTTTCTGTTGAATAGTAATATGTGTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCATTGGTGTCTAATGACTGTGGTGCTGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CGTGTACATGATGTGGTCGTCCCCAATGTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTAGATACAGGTAATCTGTGGGTATTGTGTG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAAAGC	TTCACCTACAATTAATGTATTACCCTTTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TAATAACGGAGCGTTAAAGGCTTGGAGTTA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CGGGGTCGCTTCCACATATCCTGTGGTCCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGTTGGTCCGACAACTTCCGCAGCTCTTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGGTCGTCGTCGGTTAAGTACCACTCATG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGTGGCGTTGGCTAACGTTGTTGAGGGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC

>NZ_CP012294|2|2|1237641-1239921|CRISPRCasFinder
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AGGTATCGTTTGTAATCCTACGAGTGCAAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGATACCAGTGCCGTTTAACGCTGACATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATAAAACATGATAAAGACGTTCAGCATGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATTATATGCAGATCCTAATGTTGAACTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTGATTAGTTTGGTCTCACAATCCAAGC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACGCAAGACCAAATTGATTCTGGCCCAGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATGGACGTTCATGTATGGCTCATTCTCAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCCGTTTGGGTTTGGCCTTGAACATAATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTATTACAGGGCTTACATTGCCTACGCGG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAAGTTTGTGCTGCCAATGGCAGGAACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATTAACAATCGCAAACTCACCATTTCCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTTTGTCCGAACCGTGCGTCATGCACATCT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TACTCAATCGCAAATTGATTCCGCACCAGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTTAGGCCTTCCACAGTAAAGCTAATTTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATTCGACTATCCCGGATTGATTGGAGATTC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTCGGTACGCAATAACCTTGCCGCCACGTC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACCCTTCGATTACTAACCCGCTTAATCTGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATGATGATTGCGTGCAGTAGGTGGTATAC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAACGTTGATTGATAACGGTGTAGCAGAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGT	GGTAAGACTGTTTACAGTCCCTCGATAAGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TCATCTCCTCCGATTGCATCTGTATCTAGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGCCGACATTGCCGAGACCCCAACCAGCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TTAGCTTATGCCAACATTGGTGGTAATGAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTGAGAGC	TTCGCTTTCTGTTGAATAGTAATATGTGTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCATTGGTGTCTAATGACTGTGGTGCTGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CGTGTACATGATGTGGTCGTCCCCAATGTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTAGATACAGGTAATCTGTGGGTATTGTGTG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAAAGC	TTCACCTACAATTAATGTATTACCCTTTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TAATAACGGAGCGTTAAAGGCTTGGAGTTA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CGGGGTCGCTTCCACATATCCTGTGGTCCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGTTGGTCCGACAACTTCCGCAGCTCTTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGGTCGTCGTCGGTTAAGTACCACTCATG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGTGGCGTTGGCTAACGTTGTTGAGGGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TAATGTAAAAAAGCTTGACTGTATACACAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGGAA

>NZ_CP012294|2|1|1237641-1239921|CRT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AGGTATCGTTTGTAATCCTACGAGTGCAAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGATACCAGTGCCGTTTAACGCTGACATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATAAAACATGATAAAGACGTTCAGCATGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATTATATGCAGATCCTAATGTTGAACTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CACTGATTAGTTTGGTCTCACAATCCAAGC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACGCAAGACCAAATTGATTCTGGCCCAGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATGGACGTTCATGTATGGCTCATTCTCAAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCCGTTTGGGTTTGGCCTTGAACATAATC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTATTACAGGGCTTACATTGCCTACGCGG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAAGTTTGTGCTGCCAATGGCAGGAACGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CATTAACAATCGCAAACTCACCATTTCCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTTTGTCCGAACCGTGCGTCATGCACATCT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TACTCAATCGCAAATTGATTCCGCACCAGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGTTAGGCCTTCCACAGTAAAGCTAATTTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ATTCGACTATCCCGGATTGATTGGAGATTC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTCGGTACGCAATAACCTTGCCGCCACGTC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	ACCCTTCGATTACTAACCCGCTTAATCTGA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TATGATGATTGCGTGCAGTAGGTGGTATAC
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	AAAACGTTGATTGATAACGGTGTAGCAGAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGT	GGTAAGACTGTTTACAGTCCCTCGATAAGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TCATCTCCTCCGATTGCATCTGTATCTAGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TGCCGACATTGCCGAGACCCCAACCAGCTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TTAGCTTATGCCAACATTGGTGGTAATGAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTGAGAGC	TTCGCTTTCTGTTGAATAGTAATATGTGTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GCCATTGGTGTCTAATGACTGTGGTGCTGT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CGTGTACATGATGTGGTCGTCCCCAATGTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CTAGATACAGGTAATCTGTGGGTATTGTGTG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAAAGC	TTCACCTACAATTAATGTATTACCCTTTAA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TAATAACGGAGCGTTAAAGGCTTGGAGTTA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CGGGGTCGCTTCCACATATCCTGTGGTCCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGTTGGTCCGACAACTTCCGCAGCTCTTT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	CCGGTCGTCGTCGGTTAAGTACCACTCATG
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	GTGTGGCGTTGGCTAACGTTGTTGAGGGCA
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGAGC	TAATGTAAAAAAGCTTGACTGTATACACAT
GTTTTAGAAGAGTGTCGAATCAATATAGTTAAGGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012294.1\|WP_046871860.1\|1226909_1227758_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
NZ_CP012294.1\|WP_046871856.1\|1230674_1231187_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP012294.1\|WP_056986236.1\|1227814_1228318_-\|transcription-elongation-factor-GreA	unknown	unknown	gnl\|CDD\|234693
NZ_CP012294.1\|WP_046871857.1\|1230213_1230459_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_062913272.1\|1229673_1230156_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP012294.1\|WP_046871853.1\|1236635_1236941_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP012294.1\|WP_062913273.1\|1231381_1235539_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP012294.1\|WP_056985953.1\|1245961_1247305_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP012294.1\|WP_062913274.1\|1236937_1237543_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP012294.1\|WP_046872091.1\|1242521_1243433_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP012294.1\|WP_062913275.1\|1248031_1249402_+\|Nramp-family-divalent-metal-transporter	unknown	unknown	gnl\|CDD\|234815
NZ_CP012294.1\|WP_081113859.1\|1241218_1242034_+\|DUF1275-domain-containing-protein	unknown	unknown	gnl\|CDD\|377734
NZ_CP012294.1\|WP_046872501.1\|1240604_1241078_+\|CinA-family-protein	unknown	unknown	gnl\|CDD\|334938
NZ_CP012294.1\|WP_046870605.1\|1247526_1247988_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|238182
NZ_CP012294.1\|WP_046871859.1\|1228555_1229557_-\|zinc-binding-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223677
NZ_CP012294.1\|WP_056985954.1\|1245078_1245639_+\|UbiX-family-flavin-prenyltransferase	unknown	unknown	gnl\|CDD\|223241
NZ_CP012294.1\|WP_046870608.1\|1251906_1253253_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181958
NZ_CP012294.1\|WP_046872502.1\|1240050_1240512_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225064
NZ_CP012294.1\|WP_062913276.1\|1249978_1251727_+\|pyruvate-oxidase	unknown	unknown	gnl\|CDD\|213733
NZ_CP012294.1\|WP_046871854.1\|1235755_1236658_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851

Protein	Function_ID	Function_description	E-value
NZ_CP012294.1\|WP_046871860.1\|1226909_1227758_+\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	7.19686e-120
NZ_CP012294.1\|WP_046872501.1\|1240604_1241078_+\|CinA-family-protein	gnl\|CDD\|334938	pfam02464, CinA, Competence-damaged protein. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. This Pfam family consists of putative competence-damaged proteins from the cin operon. Some members of this family have nicotinamide mononucleotide (NMN) deamidase activity.	4.91686e-55
NZ_CP012294.1\|WP_056986236.1\|1227814_1228318_-\|transcription-elongation-factor-GreA	gnl\|CDD\|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	9.41281e-52
NZ_CP012294.1\|WP_062913275.1\|1248031_1249402_+\|Nramp-family-divalent-metal-transporter	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	0
NZ_CP012294.1\|WP_062913272.1\|1229673_1230156_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.12935e-09
NZ_CP012294.1\|WP_046871853.1\|1236635_1236941_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.81667e-24
NZ_CP012294.1\|WP_062913273.1\|1231381_1235539_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	7.84327e-145
NZ_CP012294.1\|WP_056985953.1\|1245961_1247305_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.13793e-52
NZ_CP012294.1\|WP_062913274.1\|1236937_1237543_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.1362e-66
NZ_CP012294.1\|WP_046872091.1\|1242521_1243433_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.53013e-41
NZ_CP012294.1\|WP_046871856.1\|1230674_1231187_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	2.0356e-37
NZ_CP012294.1\|WP_081113859.1\|1241218_1242034_+\|DUF1275-domain-containing-protein	gnl\|CDD\|377734	pfam06912, DUF1275, Protein of unknown function (DUF1275). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although most members have 6 TM regions, and may be putative permeases.	3.46145e-44
NZ_CP012294.1\|WP_046870605.1\|1247526_1247988_+\|universal-stress-protein	gnl\|CDD\|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	3.17299e-09
NZ_CP012294.1\|WP_046871859.1\|1228555_1229557_-\|zinc-binding-alcohol-dehydrogenase-family-protein	gnl\|CDD\|223677	COG0604, Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only].	9.52511e-33
NZ_CP012294.1\|WP_056985954.1\|1245078_1245639_+\|UbiX-family-flavin-prenyltransferase	gnl\|CDD\|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	8.93354e-100
NZ_CP012294.1\|WP_046870608.1\|1251906_1253253_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	1.92234e-116
NZ_CP012294.1\|WP_046872502.1\|1240050_1240512_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	3.09841e-57
NZ_CP012294.1\|WP_062913276.1\|1249978_1251727_+\|pyruvate-oxidase	gnl\|CDD\|213733	TIGR02720, Pyruvate_oxidase, pyruvate oxidase. Members of this family are examples of pyruvate oxidase (EC 1.2.3.3), an enzyme with FAD and TPP as cofactors that catalyzes the reaction pyruvate + phosphate + O2 + H2O = acetyl phosphate + CO2 + H2O2. It should not be confused with pyruvate dehydrogenase [cytochrome] (EC 1.2.2.2) as in E. coli PoxB, although the E. coli enzyme is closely homologous and has pyruvate oxidase as an alternate name. [Energy metabolism, Aerobic].	0
NZ_CP012294.1\|WP_046871854.1\|1235755_1236658_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	8.74374e-100

>NZ_CP012294.1|WP_062913274.1|1236937_1237543_+|type-II-A-CRISPR-associated-protein-Csn2
MNITYYPFKPIIINTTKPTLIETSNQKVYTDLISGLKGYSDVIKISDDDFKLVECERAVKWVGDAFVDADLNKMFQGQLQKKIVSKLDDDTRLQLTDLNNKLKSLIFDATFSLDLPLKVDSEFDPVKLVKYCNVGFVSALNRDPYDIIETVLKTASELKETKILILTNVRNYLSVSQFNELVSLISTLDLNILFIEFSDNR
>NZ_CP012294.1|WP_046871853.1|1236635_1236941_+|CRISPR-associated-endonuclease-Cas2
MRLMVMFDLPVETSEDRRNYRKFRKALLNEGFLMVQYSIYVRVCVDKKSANLMEKRIATFSPANGLIQSLMVTEKQYNSMNFIVGESKQDVRNSADRTIII
>NZ_CP012294.1|WP_046871854.1|1235755_1236658_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVTQHAKISYSGHCVVVQTQDSTNQIPVSDIQILLISTTRAVITSAVISELAKHQSKVIFTDNSGEPVTETMDYYPNNRDPQLLQTQFNWNEERKTSLWTKIIVQKITNQIYVTEALGINAQDLKDELAKLEINDVTNREAVVARKYFSLLFESESSRRNFSPINAALNYGYAIILSAVNREIAANGYLTQLGVHHHSQENDFNLGSDLMEPFRPIVDWWVKQKKFNDFTPDIKFGLVDLLNLKMKYNGQNTILRNAITKHVDNCLKYLSGEIDKIKIEVEISEVSNNAINGHV
>NZ_CP012294.1|WP_062913273.1|1231381_1235539_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTNEKYSIGLDIGTSSIGFAVVNDNNRVIRVKGKNAIGVRLFDEGKAAADRRSFRTTRRSFRTTRRRLSRRRWRLKLLREIFDAYITPVDEAFFIRLKESNLSPKDSKKQYSGDILFNDRSDKDFYEKYPTIYHLRNALMTEHRKFDVREIYLAIHHIMKFRGHFLNATPANNFKVGRLNLEEKFEELNDIYQRVFPDESIEFRTDNLEQIKEVLLDNKRSRADRQRTLVSDIYQSSEDKDIEKRNKAVATEILKASLGNKAKLNVITNVEVDKEAAKEWSITFDSESIDDDLAKIEGQMTDDGHEIIEVLRSLYSGITLSAIVPENHTLSQSMVAKYDLHKDHLKLFKKLINGMTDTKKAKNLRAAYDGYIDGVKGKVLPQEDFYKQVQVNLDDSAEANEIQTYIDQDIFMPKQRTKANGSIPHQLQQQELDQIIENQKAYYPWLAELNPNPDKKRQQLAKYKLDELVTFRVPYYVGPMITAKDQKNQSGAEFAWMIRKEPGNITPWNFDQKVDRMATANQFIKRMTTTDTYLLGEDVLPAQSLLYQKFEVLNELNKIRIDHKPISIEQKQQIFNDLFKQFKNVTIKHLQDYLVSQGQYSKRPLIEGLADEKRFNSSLSTYSDLCGIFGAKLVEENDRQEDLEKIIEWSTIFEDKKIYRAKLNDLTWLTDDQKEKLATKRYQGWGRLSRKLLVGLKNSEHRNIMDILWITNENFMQIQAEPDFAKLVTDANKGMLEKTDSQDVINDLYTSPQNKKAIRQILLVVHDIQNAMHGQAPAKIHVEFARGEERNPRRSVQRQRQVEAAYEKVSNELVSAKVRQEFKEAINNKRDFKDRLFLYFMQGGIDIYTGKQLNIDQLSSYQIDHILPQAFVKDDSLTNRVLTNENQVKADSVPIDIFGKKMLSVWGRMKDQGLISKGKYRNLTMNPENISAHTENGFINRQLVETRQVIKLAVNILADEYGDSTQIISVKADLSHQMREDFELLKNRDVNDYHHAFDAYLAAFIGNYLLKRYPKLESYFVYGDFKKFTQKETKMRRFNFIYDLKHCDQVVNKETGEILWTKDEDIKYIRHLFAYKKILVSHEVREKRGALYNQTIYKAKDDKGSGQESKKLIRIKDDKETKIYGGYSGKSLAYMTIVQITKKNKVSYRVIGIPTLALARLNKLENDSTENNGELYKIIKPQFTHYKVDKKNGEIIETTDDFKIVVSKVRFQQLIDDAGQFFMLASDTYKNNAQQLVISNNALKAINNTNITDCPRDDLERLDNLRLDSAFDEIVKKMDKYFSAYDANNFREKIRNSNLIFYQLPVEDQWENNKITELGKRTVLTRILQGLHANATTTDMSIFKIKTPFGQLRQRSGISLSENAQLIYQSPTGLFERRVQLNKIK
>NZ_CP012294.1|WP_046871856.1|1230674_1231187_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MKISVPTSNGLLLDKYSKHAAPEQIYNGNPSISFPIDIQDVPDNATTLALTLLDFDAVPVCGFPWIHWTAVNIPADKSVTIPENASQSNVIDFIQGNNSTAGSLIGATDPLTTRHYIGPTPPDKNHDYWLSIYALDTTLSLQNGFWLNEFYHAAKGHIISKQRLSIISRA
>NZ_CP012294.1|WP_046871857.1|1230213_1230459_-|hypothetical-protein
MLLNSKNLSVLEVQVLGIYQAKIEVKTISGKCLFVYPTQTQKDDPLFWQSLKDIIKAKLWLPINKTLNQLIDSDWLVPLNT
>NZ_CP012294.1|WP_062913272.1|1229673_1230156_+|winged-helix-DNA-binding-protein
MDEKQYQTITQLLKQLSATENHNQHEVWIAKQAAIKENPQKNHLTHNDLDILGVLLQGEKTVSEVVEAVQITQGGTSRRINHLEKLDLLEKFKRPTNKKTVYLKLTADGQKLATAHIALHKHLHEETVQALAEFSDSELAVVTRFLRKLADAQKDFETRY
>NZ_CP012294.1|WP_046871859.1|1228555_1229557_-|zinc-binding-alcohol-dehydrogenase-family-protein
MKALIIKDFKTAPMIDLNVPTPVADTKFDTLIDVLAAPIENFDKANATGRHYSSTYWHPAFPSIPGASGIGRRVDNGKLVAFPARTLKPRFGSFAEQTVANSKLLFEIPEDTDIYSSTAAASSLTTSIAPLQFSLEMKPGNTVLINGATGFAGQLAIQAAKALGAAEIIGTGRNPERLAALKDLGATQTISLADDDETILNNLSNMKIKGDLIILDYLWGHPIELILKSIVPTSLEMKRATSLVSIGAIAGQNITLPSTALRTSGLQIIGMQTPKVMQNQQAVYQAVWKLLGTGKIKTTVKTISLEDAAKDIDWQKPVPSGVRTVIKVSEIKR
>NZ_CP012294.1|WP_056986236.1|1227814_1228318_-|transcription-elongation-factor-GreA
MEAIKLVREATMSEPYFNKITATGYHEIEKEIEELKAKRPALTKRLAAAAALGDRSENAEYTFSKRDLRQLESRLHFLNKQLQYSKIVQPTNNQIVEIGKKVTIEFVDDHDQMDYQLVGKQEADIKTNKISLVSPLGSALLNKTVGDIVTIHAPEETYQVKILSVNL
>NZ_CP012294.1|WP_046871860.1|1226909_1227758_+|aldo/keto-reductase
MSVLTDTFELANGVKIPKVGFGTWQTPAGDVAYQAVRNALKVGYRHIDTAKAYGNEEDVGRAVRDSGIARDQIFVTSKLPAHSKTYDEAMADFESTFKKLNIDYVDLYLVHAPWPWDEIGKDCDKGNVEVWRAMQDIYASGRVKAIGVSNFNVHDLKNVLADAKVKPMVNQIQYYVGYTEPKITSFAKQNGILVEAYSPLATGGLLKNDQMLALAKENKVSVAQLALRFCLQNNILPLPKAVGQSHIEDNAKLDFEISDEDMEKLNGMPDTAPEHSHNKTQG
>NZ_CP012294.1|WP_046872502.1|1240050_1240512_+|GNAT-family-N-acetyltransferase
MQVTVKSFSELSNTELFKIYKLRTQVFVVEQLCAYQEVDDEDLIAQHLQFTNEAQQLVAYLRIIPETNETIVHIGRVVVNPLFRKQGYGRKLITSGLETIKKDMPKVTTVKIQAQAYLRSFYQSFGFKPVSDVYLDTGIPHLDMILELQGNKK
>NZ_CP012294.1|WP_046872501.1|1240604_1241078_+|CinA-family-protein
MDEKLVNYVINTLIEENLSITAAESLTGGLFQSEITTVPGSSAVFSGGFVTYADEVKTQLLSVPKELIQQYGVVSYEVAVAMAQGAQKVLKTDLAISFTGAAGPTGLEGEDAGTAWIGITFHGQTDAYDLRKPELERNAFREACCQFAFQKISDLLV
>NZ_CP012294.1|WP_081113859.1|1241218_1242034_+|DUF1275-domain-containing-protein
MRRHVYPAYQQLYFGAFLAAIAGGLDAYTYLQHGGVFAGLQTGNLILLGVSLSKGQFVKVGYYLIAIIAFGLGTIFIRHMQHFFKQNYLKRAYFVLGYEFVLMVLVAMISQRAPDVITVMLLAITAAAQLQEFRKLQDGPFTSLMMTGNIRTTAENLYTGYVHHDVTAQQKATDTGIVIGSFAAGAFLSGIFVPWLKDAAILVPTVLVLGAVFYLAQHSKSTPNRKDPQSDSNEKAWSETTRASVHPHTSEDDTKTDSEPETRSSRRRRKL
>NZ_CP012294.1|WP_046872091.1|1242521_1243433_-|LysR-family-transcriptional-regulator
MTIDDLKDFVTLYQTRNVSDAAVELMMTQSALSKRIQAMENELATKLISTKNKRHLVITESGEVFFRYAKTILTQYGLLTNELAEYRELKKGTLHIGSVPVMSQYGLMEKTSQFMADYPQINIRLEELEGEELLEMLQTKQLDLGILRNMQSQLLNKSQFQFIDIDQDELKIILPITHPLAKQKRISMNNLRDIEVVSLNPGSGIYEQVGNLYQQAGFTPNIRFTSTHIETLLGIIAKSERVTFLFEKSAEPFMTDQFVSRSFETPIYNKLQLVYPQGELTQAGRRFVGYMEVSGTKRLKHKN
>NZ_CP012294.1|WP_056985954.1|1245078_1245639_+|UbiX-family-flavin-prenyltransferase
MKKIIVGITGASGTVYAIDLLEKLHQLDDVEVHLVMSQWAKKNLELETDYSLQQIKALADKTYNVNDQGATIASGSFLNDGMVIVPASMKTVATIAYGIGDNLIARAADVTIKEQRKLVIVPRETPLSVIHLENLTKLAKIGAQIIPPMPAFYNHPKTIQDLVNHQTMKVLDAFGIPNEVDERWKE
>NZ_CP012294.1|WP_056985953.1|1245961_1247305_+|MFS-transporter
MGILVETSLNVTMNTLSNQFGVSVGTVQWITTAYLLLVTIMMAAMAFIMRRFKFRSIFIFSAAAFIVGSIVCAIADSFWILLIGRMIQAIATGLATPLMFQIINVKIPRQHVGTYNGVASMLTSLSPALGPTYGGILNTLMNWRWIFWVVLPLSVIVLIMGMINIDIPVQHKRGEKLSFDSIGMVWLSLVLIGFVWTFNEAGLAGWTSAAFWISLVISILLLLSYAWYNSKSSKEVLDFSLLKKKSVFLHLINYFVLAFVNIGISWLLPMVAEVNLHQTSMVAGLLVLPGALIGAIISPSTGAIMDKKGAFLPLMIGNICLLASVVLFFFLNDVMTSMILLILFVILRVGVAFSFGNVMGAASQQVVPEKRGDINSLFNMMQQYAGAMGTVILASVISSLELHGGSTFSQVRQGSKIDYVILSVLALVALITVIINKSTRNHMTKNN
>NZ_CP012294.1|WP_046870605.1|1247526_1247988_+|universal-stress-protein
MQVDKLKEPLVFHRVLLTVDADDPNSSTRAFQYATTMAHDYQVELCIVSVLEDDDISIFDVMTPGKVDKKEDVVRQAVEDYTTIAEELGVKHVTGLTVGASDVDDVILDKVIPRFKPDLIVCGSDTEDSKHRVPGAVGLRIAKRAQVSVIVVR
>NZ_CP012294.1|WP_062913275.1|1248031_1249402_+|Nramp-family-divalent-metal-transporter
MAKNSNEEKHHIISSTDGANKSLDEINGSVSVPQNAGVFKTFLAYLGPGVLVSVGYMDPGNWITSISGGAQFKYRLLSVVLISSLIAMLLQAMAARLGIVTGRDLAQLTREKTSKFGGIVLFIITELAIMATDVAEIIGSAIALELLFGFPLIVGIIITTFDVLLLMLLMKLGFRKIEAIVATLVAVILFVFLYEVILAQPNMPEVLKGFAPGKDLIQNKSMLYIGLGIVGATVMPHNLYLGSSISQTRNFDRNDHKSIRSAIRYTVADSNMQLTVAFVVNCLLLILGAALFFGTNSDLGRFVDLYNALGDSKIVGAIASPVLSTLFAVALLSSGQSSTITGTLSGQIIMEGFIRLKMPMWAQRLVTRLVSVLPVLAFAIYYHGNEAKIENLLTFSQVFLSIALPFAMIPLILFTSSKKIMGEFANRPWVKVCAWIAAVVLVILNVWLIITTVSAL
>NZ_CP012294.1|WP_062913276.1|1249978_1251727_+|pyruvate-oxidase
MSKTINAGIAMMKVIEDWDVKQVYGIPGGSINSTMEALRVEQDKIDYVQVRHEEVGAFAAAAHAKLTGKIGVCFGSAGPGATHLFNGLYDAQMDHAPVLAIIGQVGTSDMNWDSFQEMNENPMFADVSVYNRTVMTADSLPHVIDEAIRRAYKENGVAVVTIPNDFGTKDIPADFWSSGHSYVKPLLPQPDEEKIKAALKLISEAKHPVIFAGIGVNGATEELVTLSKHLKLPVVMSAISKGMIPDDFEGNMGSAYRVSTKPGNETLEQADLIMMIGADFPFARTKGMFNPDAKFIQVDIDSSKIGKRHNVDVPILSDAKQAMKQLVALSDEVAHRRFYDACVANRKNWRAYLQQLADKTTSPLGVGSVFKQINRISTGNDVFAIDVGDVTMNSLRFLNMNEKQKFTTSALFATMGYGMGAAIAGKLTYPDRQVFNLTGDGAFAMVMQDLLTQVKEKLHIINVVFSNESFDFIKDEQEDEKQKYFGMDLQGADFAMIAHGMGALGISVHTYDEMVAAFDTAKQVEGPVVIDVKIHNNRPLPAEKLQLDPATNSAAEIAAFKKRYDADILQPFSVYLNEFEVE
>NZ_CP012294.1|WP_046870608.1|1251906_1253253_+|FAD-dependent-oxidoreductase
MKIIVIGATHAGTFATKQILTEHPDYDVTVYERNDNLSFLSCGIALWVGDHVSDPNKMFYSSPGELTKLGATMKMRHDVLSVDPDKKVIRVKDLVSGELFQDHYDKLVMTTGSAPVIPPIKGVDNSKVKLCKDWNDAKILKETTPDAKSAVIVGAGYIGAELAEQLAVAGKKVTLIDGLPHVLAKNFDLEIGSRVEKDYEDHGVKLAMNEMVQSFTGNDQVTVTTSKNSYTADFAVLCAGFRPATDLLKGKVKMLKNGAIVIDEYMRSSDPDILAAGDSAVVHYNPTGKVDYIPLATNAIRQGILIGHNIEKPTMKYMGTQASSAVALFGKTLASSGLTESGAKARGVTVSTVTLEENYRPEFMLSTTPILMRLVWDPKSRVVLGGAFYSSYDCAQSANVISLAIQQKMTIDELSMVDMFFQPNFDNPLNYVNELAMAAIHKSDANSK

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Crispr_ID: NZ_CP012294_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012294_3

1517407-1517557

Orphan

Consensus_repeat	Method
AGGAGCCAGTCCGACTAGCCATTTTAATGGCGTAGCGAGGATGGACATCCG	CRISPRCasFinder

1 spacers

DinG

The CRISPR arrays of NZ_CP012294_3

>merge|NZ_CP012294|3|1517407-1517557|CRISPRCasFinder
AGGAGCCAGTCCGACTAGCCATTTTAATGGCGTAGCGAGGATGGACATCCGTCTTGAAGATAAGATTTTGCGAGAGCAAAATAGACCTTAGATTTTGAAAAGGAGCCAGTCCGACTAGCCATTTTAATGGCGTAGCGAGGATGGACATCCG

>NZ_CP012294|3|3|1517407-1517557|CRISPRCasFinder
AGGAGCCAGTCCGACTAGCCATTTTAATGGCGTAGCGAGGATGGACATCCG	TCTTGAAGATAAGATTTTGCGAGAGCAAAATAGACCTTAGATTTTGAAA
AGGAGCCAGTCCGACTAGCCATTTTAATGGCGTAGCGAGGATGGACATCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012294.1\|WP_100078054.1\|1528098_1528221_-\|AbrB-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP012294.1\|WP_062913328.1\|1530098_1531532_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237177
NZ_CP012294.1\|WP_062913325.1\|1512335_1512608_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_046871692.1\|1527185_1527620_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NZ_CP012294.1\|WP_046871689.1\|1518449_1519367_+\|ribonucleoside-hydrolase-RihC	unknown	unknown	gnl\|CDD\|182713
NZ_CP012294.1\|WP_081113881.1\|1517686_1518340_+\|class-A-sortase	unknown	unknown	gnl\|CDD\|320680
NZ_CP012294.1\|WP_046871683.1\|1508150_1510520_+\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NZ_CP012294.1\|WP_046871693.1\|1527641_1527842_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_CP012294.1\|WP_046871691.1\|1526439_1527129_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_052694520.1\|1525045_1526425_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|119383
NZ_CP012294.1\|WP_056986240.1\|1523268_1524699_-\|SEC10/PgrA-surface-exclusion-domain-containing-protein	unknown	unknown	gnl\|CDD\|275124
NZ_CP012294.1\|WP_145930492.1\|1512827_1514933_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|380246
NZ_CP012294.1\|WP_046871675.1\|1499843_1501256_+\|C69-family-dipeptidase	unknown	unknown	gnl\|CDD\|335383
NZ_CP012294.1\|WP_056986623.1\|1528537_1529914_-\|ISLre2-family-transposase	unknown	unknown	gnl\|CDD\|284250
NZ_CP012294.1\|WP_046871682.1\|1502796_1507173_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_046871684.1\|1510732_1512025_+\|nucleoside-permease	unknown	unknown	gnl\|CDD\|224883
NZ_CP012294.1\|WP_010620873.1\|1501465_1502638_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_CP012294.1\|WP_046871687.1\|1515046_1516471_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|227268
NZ_CP012294.1\|WP_062904010.1\|1507375_1507984_-\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|237555
NZ_CP012294.1\|WP_046871671.1\|1498271_1499714_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|237929

Protein	Function_ID	Function_description	E-value
NZ_CP012294.1\|WP_062913328.1\|1530098_1531532_+\|hypothetical-protein	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0.000615286
NZ_CP012294.1\|WP_046871692.1\|1527185_1527620_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	4.40396e-10
NZ_CP012294.1\|WP_046871693.1\|1527641_1527842_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	1.04475e-06
NZ_CP012294.1\|WP_081113881.1\|1517686_1518340_+\|class-A-sortase	gnl\|CDD\|320680	cd06165, Sortase_A, Sortase domain found in class A sortases. Class A sortases are membrane-bound cysteine transpeptidases distributed in Gram-positive bacteria (mainly present in Firmicutes). They perform a housekeeping role in the cell as members of this group are capable of anchoring a large number of functionally distinct surface proteins containing a cell wall sorting signal to an amino group located on the bacterial cell wall. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is cleaved at a conserved cell wall-sorting signal (Class A sortases recognize a canonical LPXTG motif, X can be any amino acid), and covalently linked to peptidoglycan for display on the bacterial surface. The prototypical sortase A protein from Staphylococcus aureus (named Sa-SrtA) cleaves the amide bond between threonine and glycine residues of the canonical LPXTG motif in a wide range of protein substrates with diverse functions that can promote bacterial adhesion, nutrient acquisition, host cell invasion, and immune evasion. Next, it catalyzes a transpeptidation reaction by which the proteins are covalently linked to the peptidoglycan precursor lipid II. SrtA is therefore affects the ability of a pathogen to establish successful infection. SrtA contains an N-terminal hydrophobic segment, a linker region and an extra-cellular C-terminal catalytic domain. The hydrophobic segment functions as both a signal peptide for secretion and a stop-transfer signal for membrane anchoring. The catalytic domain contains the catalytic TLXTC signature sequence where X is usually a valine, isoleucine or a threonine. The gene encoding SrtA is generally not located in the same gene cluster as its substrates while the gene encoding SrtB is usually clustered in the same locus as its substrate.	1.72347e-59
NZ_CP012294.1\|WP_046871683.1\|1508150_1510520_+\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	5.61493e-66
NZ_CP012294.1\|WP_046871671.1\|1498271_1499714_+\|amino-acid-permease	gnl\|CDD\|237929	PRK15238, PRK15238, inner membrane transporter YjeM; Provisional.	1.41105e-32
NZ_CP012294.1\|WP_145930492.1\|1512827_1514933_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|380246	NF033396, pilus_ancill_1, pilus ancillary protein 1.	7.5615e-05
NZ_CP012294.1\|WP_046871675.1\|1499843_1501256_+\|C69-family-dipeptidase	gnl\|CDD\|335383	pfam03577, Peptidase_C69, Peptidase family C69.	0
NZ_CP012294.1\|WP_056986623.1\|1528537_1529914_-\|ISLre2-family-transposase	gnl\|CDD\|284250	pfam06782, UPF0236, Uncharacterized protein family (UPF0236).	7.72905e-36
NZ_CP012294.1\|WP_010620873.1\|1501465_1502638_-\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	7.20386e-123
NZ_CP012294.1\|WP_046871684.1\|1510732_1512025_+\|nucleoside-permease	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	6.24557e-113
NZ_CP012294.1\|WP_046871689.1\|1518449_1519367_+\|ribonucleoside-hydrolase-RihC	gnl\|CDD\|182713	PRK10768, PRK10768, ribonucleoside hydrolase RihC; Provisional.	0
NZ_CP012294.1\|WP_046871687.1\|1515046_1516471_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|227268	COG4932, COG4932, Predicted outer membrane protein [Cell envelope biogenesis, outer membrane].	5.23349e-07
NZ_CP012294.1\|WP_052694520.1\|1525045_1526425_+\|hypothetical-protein	gnl\|CDD\|119383	cd06523, GH25_PlyB-like, PlyB is a bacteriophage endolysin that displays potent lytic activity toward Bacillus anthracis. PlyB has an N-terminal glycosyl hydrolase family 25 (GH25) catalytic domain and a C-terminal bacterial SH3-like domain, SH3b. Both domains are required for effective catalytic activity. Endolysins are produced by bacteriophages at the end of their life cycle and participate in lysing the bacterial cell in order to release the newly formed progeny. Endolysins (also referred to as endo-N-acetylmuramidases or peptidoglycan hydrolases) degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.	1.09236e-44
NZ_CP012294.1\|WP_056986240.1\|1523268_1524699_-\|SEC10/PgrA-surface-exclusion-domain-containing-protein	gnl\|CDD\|275124	TIGR04320, hypothetical_protein, SEC10/PgrA surface exclusion domain. This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.	2.23364e-33
NZ_CP012294.1\|WP_062904010.1\|1507375_1507984_-\|C40-family-peptidase	gnl\|CDD\|237555	PRK13914, PRK13914, invasion associated endopeptidase.	1.43228e-30

>NZ_CP012294.1|WP_046871687.1|1515046_1516471_+|LPXTG-cell-wall-anchor-domain-containing-protein
MIATKKGFFKKIGAGLLVAAAMAPLALGLTSIKSVSAADDKVTVSLHKMVRDQGTTGGITSDGTNQGTINGFSDWNKSSHGDVEFSIYSVDSAFTAWKAKPGTPSYDNDGDAFNAFQKYILDFGDDHTALLADLGITEADQTIDSRKDENNANLFNFTQITNSGKYMILETYADASHTTTKAAPIVFNLPLEKATGDTVHLYAKNDVPKTDPELEKKMENPNEPGEFIFKSGIKFTLTKDTGDFTPVESSTNAQGRIKIENLAAGDYTLTETAVDGYTPITIKFNVSGGNITITDSPDDVHAKKEGSVWTIYAKNFLKFGEKDFTKIDSKDSEKLAGAVFYVKNNSVLGQGEFAQFEGGKFVKWVANKENATPFTSGDGDNGTTLGAFNIPLMPYGTYYLEEDVAPNHYGKLDSTIPFTIDGDSEAEAAKEIKNTKYDLPITGGMGIWVFVLVGAVLMGGAGFYYYKSRKNKLI
>NZ_CP012294.1|WP_145930492.1|1512827_1514933_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKFSGLKENVKFGSLSFLAPVENEKVESEDSSATEKESETSKEESQSSGSTESEDNDDADTDVDQNSRARTNSDTGSATEKATRAVTEIPLPEFPDRSGNPLGVAANFHIFAENFARGGNAHTSGNIAVNSLTNVSEIGNEGRDTRWQETSYVKAYDGRRDRLTFRAAVFGNEHSLTDINNGAQTFLTGGPLGTGRVSYQYNNSGDNITGAAINGNWIDVTDTLTTLKQTRDNLVNTPYAIDFDDTRYLTEDSNGLTLNFEDEAVQNTFVIKVSNSQIAGKTLNIKLRDEQNVIFVATPDKDSGALGSAHMHVYVDGELIGPDPEAGKGTRYNYSILWAIPEGSEEVNLVGNMFFGSVLAPSQTVQSYTNFNGTIVADTYLGSSAETHSWTYNPTTEVEPEPEETQLVVKKTVEGSDDDKNKEFKFVITRLDEENFDGTLKMKINGQGEEINLKFTDGKSEEITLKHGQYVSLVVPNGSRFSINETEAHGASTGIEIDGNAVESDNRETGPVQMGEADKGQSHIVDYTNKFEEEPETKDLQIKKTVTGDVPHGTKFKFNLSIDPKKAGTYKYTAGDGSEQDITFDEDGKSTSSIELEADQTATIKGLPKDAKVTITEIDADGYKTTIKHENNGAEEKKEITIDFTTINSNSTSVVFNNHLTKPNMPVTGGIGNLIFILVGLLVVAVGGYLLYKNRRGNVNG
>NZ_CP012294.1|WP_062913325.1|1512335_1512608_+|hypothetical-protein
MAIRRVYSVLMICLLLFGIGYPATGAFAEGDKDDQFKITETEFTNENDEKLEEVDADQQVNAKFHLKMTGKQARENDSTSIKLLGTDSLT
>NZ_CP012294.1|WP_046871684.1|1510732_1512025_+|nucleoside-permease
MGNGRYLIVNIIGIFVFIGVAFLFSKDKKHVDWRSVITMLVINIFLAWFLTGFSIGIDGVKAAAGAFNWMVQISYSGIGFALASWVKVKPMDFVTSSLLPILMIVPLFDILTYIGFLPWLIKWVGRGLAFITRQPKFESFFAVEMMFLGNTEALAVSSLQLKQMKAQRLVTIAMMSMSCVTASILGAYMQMMPGEYVIAAVPINIVNAIIVTIILNPVTVTPEEDTIAKLGGSAQVEENTQTTETSGSEDLAEDQVKADMKPKKEPFFSFLGDSILGAGKLVLIILANVIAFVALAKLIDSCLQLVAPWLTMENILGVIMFPFAWLLGLDVPTAFKFAQFMGTKLVTNEFVVMGKVSPVISTYAPHFKAMLTVFLTSFANLSTTGMIIGAFKGIVDRKKNDVISKNVGYMLLSGVLVSLMSAGIVGLFSW
>NZ_CP012294.1|WP_046871683.1|1508150_1510520_+|ATP-dependent-DNA-helicase
MAAKKIGIRELVEFVLRAGDLNSSSNSQNTALEGAQIHRKLQKAGGENYEKEVYVKRTVSMAGEDYVIDGRADGVIQTADQLLIEEIKTSDPDFEDLSENTLTLYWSQAKVYGAILTHDLDLPKVTLRLTYYQRTTDEITKTEHTYTSEELQTFFDGLIEEYRNWLVMRSDWRKTRNKSIKALKFPFDEYRNGQRDLAVAVYKTIALKKRLFVEAPTGTGKTISTLFPSIKAMGEDLCDRLFYLTAKQSTRSVAEKGLQLMVDKGLQIKSITLTAKDKIIFPEEVDVAPEDNPYMIGYYDRLKDGIRDVFEHENQITRPTIEKYAKKHTLDPFEFSLDISTFMDVIICDYNYLFDPIVYLQRFFTQPEDANFFLVDEAHNLVSRSRDMYTAQVDDGDTDDLIKAGKTAGKNEDIQGITNQLKKVQTVFDQVKIPLTEQHKTQAVTTEELTGFRHGLEKFNSFVQDWLPKQPQTPFTSQILDFYFTLLRYVKISAFYDESYRVIVTIEEDQSVSVKELCLDPSPYLDMSLKMGRGVVFFSATLSPMDYFKETLGCAENGLSLQLTSPFLEQRQNILITQYVNTTYHQRENSLGSIVDSIFEMVNAKQGNYLIFCPSYKYMTQIENAFLQKYQQFNVIEQSNQMNEAARKEFLDAFAKNYPHSLIGFSVLGGIFSEGIDLVGDYLIGVAIVSVGLPGLSDERNLLRDYFDQKNGKGFEYAYQLPGMNHVLQAAGRLIRSDQDAGNVVLMDNRFGNQRYTRLFPRHWQHYQRVYSVEQLAKNVQGFWQKLDE
>NZ_CP012294.1|WP_062904010.1|1507375_1507984_-|C40-family-peptidase
MKTKSALPILLFFATFLAIFFGQSTISADSIKPIQGIQATANHTDTLSSISIPEKIQAIKSDSKANVADTSDKKATKNYSDLINLARKQLGKDYVWGAVGPDTFDCSGLTQYLFANAYNKTLPRTAAAQYAAFDHVSHDDVQPGDLVFFSYNGGASIDHVGIVVSGDNQMIDAQDRGVLKESYMASYWKPYIAGYAHVMDLK
>NZ_CP012294.1|WP_046871682.1|1502796_1507173_+|hypothetical-protein
MKKKVYKKQSSKIRRLIVMSCTIPLLSTSILPMVNISAQNVESSQKTSKKNQDVKDAEQLPDLSKKVENMAVESDDESSKKVDSNSKDKEQTELKNDNNSKDEEQVENSKNKIASEKVEEKVKDKKDARASASVTISPSEVNEWDSYSPGGLETALLILPVSIDASANTRVTYGLYFKPDSGPEHSVSHGMVTTNSVGQATWEAGAWSEKESGNYIIRFSSGMSGSTSARYTYNKAEIPTVASHTISAGVSVTFTAENINADHVAEYQWQKRERGQWADIEGATNRTYRTDGTDAVGTTEYRVTVKYGTDNVLTKTSNAATLTVTGITPTIADQSVLEGQKATFKVEEPVSGVHYQWLKKDGDSFEPISGATSSTYTTNGDEADGTQYKVKATSGSLVDESNVATLTVAELMNPEIENQEVLEGQKVTFTSEAVAGVNYQWQQWIDDEWKNIDGATNHEYETKGTEADQSKFRVRVNNGYINKYSDEAVLTVTELVKPEVADETVLEGQKATFTTEAVSGVSYQWQQLIDGDWENIAGATNHEYETKGTEADQSKFRVRANNGHINKYSNEAVLTVTELVKPTVADKTVLEGEKATFATETVSGVSYQWQQKVDGDWENIDGADKNEYETKGTEADQSEFRVKANNGHIDKYSDAAVLTVTELAKPEVADKTALEGQKATFTTEAVSGVSYQWQQLIDGDWENIDGATKHEYETKGTESDQSKFRVRANNGHINKYSNEAVLTVTELVKPTVDNETVLEGQKAIFTTKAVSGVSYQWQQLIDGDWENIDDADKNEYETKGTEADQSEFRVIADNGHVTKTSNAASLTVKELAKPSVADETVLEGQKATFSTEKDADVKSYHWQQKIDGDWKDIDGADKNEYTTEGTEADQSEFRVIVDNGYITKTSETAKLTVKELAKPTVADETVLEGQKATFTTKGGSTAKSYQWQQKIDGDWKDIDGADKNEYTTEGTEADQSEFRVIVDNGYVTKTSETAKLTVKELAKPEVADETVLEGQKATFKTKADPTAESYQWQQLIDDEWKDIDGADKTEYTTDGTDADQSKFRVNVDNGHINKYSNAAVLAVKELAKPEVADETVLEGQKVTFTTKADPTAKSYQWQQLIDDEWKDIDGADENEYTTEGTEADQSKFRVIVDNGYVTKTSNAASLTVKELAKPQVSDKTVLEGQKATFTTKADSTAKSYQWQQLIDDEWKDIDGADKNEYTTEGTEADQSKFRVIVDNGHVNKTSDAASLTVKELAKPEVKDQTVAEGQKATFVAKADSDVKSYQWQQLINGKWQDINGATNRKYTTKGTESNRSKFRVVVSNSYVTKTSDVAFLTVIKNGNTDNSGSDGQDSQKDNSNAGQSSSKNGKNQGKDANTDQSNQSLGKNVNTDQNDLKNNQNQVGNTAKAADGNDQDQTQNDKLPQSDERREIGLMIIGGLLLVLTLLAGPILRLRKKQ
>NZ_CP012294.1|WP_010620873.1|1501465_1502638_-|IS256-family-transposase
MNQFTKEIVTALAQRQDLDIIFKDQLETAVNELLQNELSAFLGYEPYDRNGFNSGNSRNGHYTRTFNTKYGELNLTIPRDRNGEFVNHTLPAYQRRTDQLEQTIIQLYQKGITTHEIADLMEKMYGSYYTPQTVSNLTKVVNEQVEAFKNRTLSERYAVVYLDATYLPLRRDTVAKEAVHIAIGIQPNGHKEVLSYKIAPTESSSVWSEVLADLKDRGVQQTLLFVADGLVGLETAVGKYYPNAVIQQCLVHVSRNISHHVRVHDRKAVLNDFKLIHQATNKRMAEHSLANFVDHWRKRYPKVTQALLKNQKLLVFFNFPPAIRSSIYSTNLIESFNKKFKRQTKKREQFPNEESLERTLMTVILDYNDKFGRRTHKGFNLVQDTLESMF
>NZ_CP012294.1|WP_046871675.1|1499843_1501256_+|C69-family-dipeptidase
MCTSVLVGKKASLDGSTMIARNEDRYLPIHPKKFYMHPAVKGQKVVLKSKLNGFEAPLPADGYRYTATPDADPNKLHEGVNDESGINEKNVAVSATESTYGNERTLAYDPLIKDGLGEDSLETMVLPYVDSAQDGVKRLGDLIAKYGSNAGNSVLFSDKDNVWYMEIVTGHYWVAQRIPDDAYAIAANEVAIQQVDFNDPDNFMWADGIQDFVEKHHLNVDAQGWNFRHIFGTFNEKDRHYNTPRVWYAQKFLNPEIEQEPESGELPFICHTTHKISVEDVEFILGSHYNETQYDPLAPGESADKYRYRPISMNRTQNSHVLQIRNNVPAEQAAIYWLNFGVPSFSPYVPFYSNATDTDDSYKNTAMSFNFSDAYWMYRTLSMMVESHYPQFVQNSRDYLTAIRETQRRYLENTDNKARDLTGSALSDYLTEQNKVLVTEMRKQTVDFIGSLVVQGAGLSKLTFNMDKNL
>NZ_CP012294.1|WP_046871671.1|1498271_1499714_+|amino-acid-permease
MGDTSTNTKQFRWFTIALIAFNTVWGFNNVVNNYAQQGASVITSWIIILAVYFIPYTLMVGQLGSTFQKSGGGVSSWIDATSTRGLAYFAAWTYWVVHVPYLAQKPQNILIAISWAFTGAGTYFSHFSTAIFSILCLIVFLFFMWVASKGITTLGVIATFAGTATFVMSILFIFLAIAAPHLPNVTAATQNLTHVKTYIPNFNFSYFTTLSMLVLAVGGSEKIAPYVNKTKNPSKEFPLGMIVLAILVGVCAIAGSVGMAILFNSKAIPKDLMMNGAYSAFQRLGQYYHIGNALMITYGLTNSIGQIAALIVSIDAPLRILLSGHNDEYVPKSLMKLNKHGVFINGYKMTGILVGILIILPGLGIKNIQQLYNWLLNLNSIVMPLRYLWVFVAFMLLSKHMNKFHSDYMFVKNKTIGWLLGFWCFIFTAFVCVLGMVPKVSFSSDPHGWFLQLGLNIITPIVLIALGFIMPMIARRDKNK
>NZ_CP012294.1|WP_081113881.1|1517686_1518340_+|class-A-sortase
MVGLLSNPLIEHMGNEEVENMTPKKVEASKRKPANFDYSSVEMLNPVSVSVEAAKNATKGFTNGLSQGDDAGDYAPLGKVSIPSVALRLPIGKGLGHEVLSRGAGTMSEDQQMGQGNYAISGHYMTNTRILFSPLKQVKISDMIYLTDMKKVYRYRTYSKRTVPKSEVEVLKEVAGKKVVTLITCASPATNEPNRIVVQGELVGTSTNLNKYKNIFG
>NZ_CP012294.1|WP_046871689.1|1518449_1519367_+|ribonucleoside-hydrolase-RihC
MTTKIIMDCDPGIDDAAAISVALNNPALAVKLITTVAGNVTVDKTTKNALKLVHFFNKKVPVASGAEQPLIKPFEDAARIHGESGMPGYNFDELVGDTVKHTAMEALYQTIMKSPEPITLVPTGAYTNIALLLATHPEVKPKISRIIAMGGSLGRGNMTSAAEFNVYTDPDAAQIMYNSGIPIVMIGLDVTMKALLTQKTLNTVGTLGEAGNMLASIFKHYYEGHEGGIPMHDVNTICYLLHPEFYQTARYWIDIQTSGPAIGETVADIRGAYHLGNTNAQVAVGIDADDFNQWFIEEVQNMKTE
>NZ_CP012294.1|WP_056986240.1|1523268_1524699_-|SEC10/PgrA-surface-exclusion-domain-containing-protein
MNKLSKIAVATLASVNMVGAGVITPSLLGQAVSVQASSSYKKVASRNIKKTAYHRKSSTGTVWNASHTKALHYLKNYSKTTWNVTKQITLKHNGKKTNYFYVKDSKNSKINGYVYTGYVTKGAYKAPGYTVTYNHKYGKVQYHRASSKSVSVWNTGHKKAVHNLKNYPTTTWYVDQTITWKSPKGAKSNYYHVIDKNNSKVNGYVWHGYVTKGAYVKPAKTTIIKPSVAADKNSIKLPAGYYSALAKYAKDADAGKSTTNDAKAIDKFAKTGSAQTYKQSSSDQAVKIDDVNKLSSTIQLQLTQFAAQLINNIRKQAGNPGVTVSKGAIDFASAVNKGYMADNWNLMEKSAHDVPAIQKAAKSFGLNADEQYYENLSVLESTNKSEYNTLADLKGGIYQSMLIFLFKDAGSSYGHAQSIAGCHTEKKTYFGFAAQHFTDGDRYAYQTHYELIPNDPFYITTPSKFNTKTTYAIPSN
>NZ_CP012294.1|WP_052694520.1|1525045_1526425_+|hypothetical-protein
MDVIHTHQRSKKSFWLKVTMVMISLLIFTGVATQHAQAATLNSQIPDLSEWQGELSASQVKKLAKVEPFIILRVQQGSDYKDKYFSHNAALCQQYGLKYGAYSYSQYSSTSDAKQEAKDLYNRAPNASFYVNDYEEQTVTSGTTNSATKAWYTELHSLTSKHVLFYSYNSFAQSYAASALKSYDGFWLASYTQAEPTGISHVLWQYTDEWNCSPIGELVDASLKKGKTNSWFVDSTSNAISYKKYVTENGAKSSYTIWKNLSFTAKSGQTGTSGKTYYAKYYYKHSNGSTYLSLYDKNGKWVGYVNANAMTVMTAHSFNHSVTIYDPNYTVWNNFVWANVKHYSKNYVNQQFTVKYQYYRGNGQAYYSLYKGNTWFGYVNANATWKAIGTNKTVQIAKQNQTIWRNLSFTKKYGSTNTYYGQTYTVKYYYNHPNGSTYYSLYNGKTWIGYINKNMVTSN
>NZ_CP012294.1|WP_046871691.1|1526439_1527129_+|hypothetical-protein
MKKQVVLASCSLILGVALLGIGGASHSQNAATIHAVTTPASSGLAAPEKVDGTNTEVQSVTGNSTSGKVTYTNGANTATAATYKQNKYQSNSQAKSSFANYHNVTETNGPKITLADGTKAVKQGVMGHVYIQWQKNGWDVTAVANSDQMGTGTVNSSNKAATKVANKVQKTLKSTKVTTKKVTHGDVVVYNSNQTKPANSISWQQGKKVARVTGVNAKTTAKIAKDTLK
>NZ_CP012294.1|WP_046871692.1|1527185_1527620_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MFASYPALFYYDKSEKVPFFITFPDFTNSATQGTSISDAMAMASDWLGITIADSLENNRNLPKPSDIKSLSLKKDNPYPNDLKYDPALSFVSMVLVDLTGYIDSGQPIKKTLTIPKWADKLGKELKLNFSQTLTDAIANKKLNN
>NZ_CP012294.1|WP_046871693.1|1527641_1527842_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MPMTQKQMVKLLKINGWIKSSGGKGSHIKMSKPVKRPITVPHGELNKFTERAIKKEADLESSQLHL
>NZ_CP012294.1|WP_100078054.1|1528098_1528221_-|AbrB-family-transcriptional-regulator
MDQKKDTFWDKVNAHVAKYGSIDTPQIDFGSDVGAEVIDD
>NZ_CP012294.1|WP_056986623.1|1528537_1529914_-|ISLre2-family-transposase
MSQILTEIMTVLKDSNNLFDAEQNLMMQCQTLIATALGQALEDLDDLLIGETEYQEIVGKRERTLNFMCGAVTFKRRLVKLTDKKYVFPLDRYLQLIPRSRFSPLMVEKVAKLASHSVLRTTALAVNLLTPLSISHQKVGQLYQTAGTQCEKQREETTLVTVAKKRQVPYLYLEGDAFCVAIKAKHHHKNIFVHRLQLTEGITQNGQRRQTLNRHVFTGLNRRVVFKQAQDYLSQNYDLQHTTVITGSDNGSGYEPSCFDELAIGAKKHEHFLDCYHLNRKIRKRLSMMPKKLQNMLFQAVHNWDSDQIQVILDTCESIASDTDSLESIQLLRRYLKRNWNYLKPAVERSLTAENVCLGGCESNHRRFTYRLKHQGRSWSIPGLKAMVNVITSEINGQLEAAMLNVPAASPINVKPVNISASHFLKQPFTQHQGIKHGSLHLDAATSSAMGNLVKIIS
>NZ_CP012294.1|WP_062913328.1|1530098_1531532_+|hypothetical-protein
MAKFHSGFRQQQRDTKHKQQADHRKKLAEFRKQQLDRQASETIAPEATAKSQSSLPKNDHEKTKYRKLKQQYTKLQKKLVASGKQNLQLSQQLNKQKRNANQTNLQQKLQAKDQQLKDNEQELQQKEAVIKRLLAEKSLANDEVLAIHEEMQRTKANFTILARHVKPKLAADEHQKQVQSLSNVLIGFLANRYLGQKTHYYQLSAADMLKLFREEIKNQETTKAEMKTVHQENQQLKIQIKAAQKAANQANLNRQIISNRFESLVNFNVEHQLHRVSTKTLLETLMTRVGRADLSEFDLLERLYDAYMRRVEPQMAQEVENQDPQIRFGFIHITENVTTFTDVNFVIHYNVKNPKQLELVNGNAYRGRLVQDDTELVLEKALPFFKRRLERVAHHNHKQRLSTNKVMPEVKSALDGKQVLIATWKRNFDYKEYLKPFGVITTVADTAEIKGDRLAMLAGAKRFDLVFCDTGGCTIAR

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Crispr_ID: NZ_CP012294_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP012294_4

1662987-1663126

Orphan

Consensus_repeat	Method
CCTCCTCGATTTTTAAATGACTATTTTGCATACGCAAAATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP012294_4

>merge|NZ_CP012294|4|1662987-1663126|CRISPRCasFinder
CCTCCTCGATTTTTAAATGACTATTTTGCATACGCAAAATCCTATTCTCGGTACGGTGTCCATCCTTGCTATGGCATTCCAATGCCAAGTCGGACTGGCCCTCCTCGATTTTTAAATGACTATGTTGCATACGCAAAATC

>NZ_CP012294|4|4|1662987-1663126|CRISPRCasFinder
CCTCCTCGATTTTTAAATGACTATTTTGCATACGCAAAATC	CTATTCTCGGTACGGTGTCCATCCTTGCTATGGCATTCCAATGCCAAGTCGGACTGGC
CCTCCTCGATTTTTAAATGACTATGTTGCATACGCAAAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012294.1\|WP_046871521.1\|1663358_1664039_+\|noncanonical-pyrimidine-nucleotidase,-YjjG-family	unknown	unknown	gnl\|CDD\|162788
NZ_CP012294.1\|WP_046871517.1\|1668933_1669257_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_046871528.1\|1657229_1658096_+\|viroplasmin-family-protein	unknown	unknown	gnl\|CDD\|260010
NZ_CP012294.1\|WP_046871525.1\|1659686_1660880_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP012294.1\|WP_046871523.1\|1662070_1662571_+\|O-acetyl-ADP-ribose-deacetylase	unknown	unknown	gnl\|CDD\|394878
NZ_CP012294.1\|WP_046871518.1\|1666396_1668292_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP012294.1\|WP_046871512.1\|1673164_1673383_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_046871524.1\|1660891_1662058_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_046871526.1\|1659160_1659541_+\|iron-sulfur-cluster-biosynthesis-family-protein	unknown	unknown	gnl\|CDD\|366687
NZ_CP012294.1\|WP_046871529.1\|1656905_1657088_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_062913363.1\|1664221_1664674_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP012294.1\|WP_046871514.1\|1671935_1672493_+\|DUF5067-domain-containing-protein	unknown	unknown	gnl\|CDD\|374759
NZ_CP012294.1\|WP_062913365.1\|1672686_1673079_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|374224
NZ_CP012294.1\|WP_062913362.1\|1654855_1656184_+\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP012294.1\|WP_046871530.1\|1656256_1656508_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_062913364.1\|1664673_1666410_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP012294.1\|WP_046871515.1\|1670399_1671482_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_046871527.1\|1658105_1658633_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP012294.1\|WP_046871522.1\|1662790_1662979_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP012294.1\|WP_046871516.1\|1669273_1670092_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223635

Protein	Function_ID	Function_description	E-value
NZ_CP012294.1\|WP_046871521.1\|1663358_1664039_+\|noncanonical-pyrimidine-nucleotidase,-YjjG-family	gnl\|CDD\|162788	TIGR02254, hydrolase_haloacid_dehalogenase-like_family, noncanonical pyrimidine nucleotidase, YjjG family. This HAD superfamily includes including YjjG from E. coli and YfnB from B. subtilis. YjjG has been shown to act as a house-cleaning enzyme, cleaving nucleotides with non-canonical nucleotide bases. This family is a member of the haloacid dehalogenase (HAD) superfamily of hydrolases which are characterized by three conserved sequence motifs. By virtue of an alpha helical domain in-between the first and second conserved motif, this family is a member of subfamily IA (TIGR01549).	1.40992e-72
NZ_CP012294.1\|WP_046871516.1\|1669273_1670092_+\|HAD-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.38745e-46
NZ_CP012294.1\|WP_046871528.1\|1657229_1658096_+\|viroplasmin-family-protein	gnl\|CDD\|260010	cd09278, RNase_HI_prokaryote_like, RNase HI family found mainly in prokaryotes. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD), residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Prokaryotic RNase H varies greatly in domain structures and substrate specificities. Prokaryotes and some single-cell eukaryotes do not require RNase H for viability.	1.14956e-55
NZ_CP012294.1\|WP_046871525.1\|1659686_1660880_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.05758e-54
NZ_CP012294.1\|WP_046871523.1\|1662070_1662571_+\|O-acetyl-ADP-ribose-deacetylase	gnl\|CDD\|394878	cd02908, Macro_OAADPr_deacetylase, macrodomain, O-acetyl-ADP-ribose (OAADPr) family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. This family includes eukaryotic macrodomain proteins such as human MacroD1 and MacroD2, and bacterial proteins such as Escherichia coli YmdB; these have been shown to be O-acetyl-ADP-ribose (OAADPr) deacetylases that efficiently catalyze the hydrolysis of OAADPr to produce ADP-ribose and free acetate. OAADPr is a sirtuin reaction product generated from the NAD+-dependent protein deacetylation reactions and has been implicated as a signaling molecule. By acting on mono-ADP-ribosylated substrates, OAADPr deacteylases may reverse cellular ADP-ribosylation.	9.67097e-95
NZ_CP012294.1\|WP_046871518.1\|1666396_1668292_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.30096e-178
NZ_CP012294.1\|WP_046871526.1\|1659160_1659541_+\|iron-sulfur-cluster-biosynthesis-family-protein	gnl\|CDD\|366687	pfam01521, Fe-S_biosyn, Iron-sulphur cluster biosynthesis. This family is involved in iron-sulphur cluster biosynthesis. Its members include proteins that are involved in nitrogen fixation such as the HesB and HesB-like proteins.	8.07463e-21
NZ_CP012294.1\|WP_062913363.1\|1664221_1664674_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.08737e-12
NZ_CP012294.1\|WP_062913365.1\|1672686_1673079_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	4.38735e-13
NZ_CP012294.1\|WP_062913362.1\|1654855_1656184_+\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.87915e-149
NZ_CP012294.1\|WP_046871514.1\|1671935_1672493_+\|DUF5067-domain-containing-protein	gnl\|CDD\|374759	pfam16729, DUF5067, Domain of unknown function (DUF5067).	7.52663e-06
NZ_CP012294.1\|WP_062913364.1\|1664673_1666410_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.80248e-161
NZ_CP012294.1\|WP_046871527.1\|1658105_1658633_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.40699e-18

>NZ_CP012294.1|WP_046871522.1|1662790_1662979_-|hypothetical-protein
MGDLTKLAEEIINYQKKHDLTDASIAFGTHLSVEKIHNIKINKYNATEDDIRRINDYMRDNK
>NZ_CP012294.1|WP_046871523.1|1662070_1662571_+|O-acetyl-ADP-ribose-deacetylase
MAFKVIRGDITTMKVDAIVNAANTTLLGSGGVDGAIHRAAGPELLAACRLLHGCQTGEAKITPGFKLPAKFVIHTPGPIWRGGHQHEAELLHNSYQNSLNLADQNHCVSVAFPSISTGVYRFPLQAGAKIAVTTIREFLKTAQSVKDVTMVCFDEGTYQAYLEVQK
>NZ_CP012294.1|WP_046871524.1|1660891_1662058_+|hypothetical-protein
MDSVLYDLEFAKNDQRLANVFPKEQETFYTGFVNSIGADGVILNTYDDTGQADGAVYVQFDAIENVEFDSPDLDNMLETIQIAENDQLFTVMDRIPDFVSTSDLIKQVVEDAYKNEQFLVLTRSDLENYQEGKVTAVHENDFEMHLVDKFDLTHEVLTTIKYTEAEIVEFSGRELAVETATWPEIAKQQPESRLTLTDTKDFYAVLKNAEQKQELITINDETKSSNFFVGTVNAVNKSEVLCNLVDMAGQFGGYSLIRLDAIVSITLKSDYMQVMEAFINYQKKNQTFVQPVLNEERLFDATDDLIMALIKQTETFSRVLSISLLTGAREMGYITDVTTDTFRFHVIDADLYVDQTGIEIVIEDVDELSFDFLNAVLIENHLRDKGLL
>NZ_CP012294.1|WP_046871525.1|1659686_1660880_+|MFS-transporter
MDDRTKQTFSWPLFLSPFVSRLGDALFVFGLNWFIVRATGHASLLGIVQGIGGIVLVAGDLFAGPLVDKYNRKLIMLLADIVSFLACLIMAGIMDVNKPVFYQLVLLTCIIDIGLAFNFPAAKAVVPEIIRSDKLSTFNSWSNTGLTLADIVAPLFGGFLLTLHWINFRSFLFINALSFLLSFIFTLALKYKPEKDHTKESMPILESLVKGLNYVRNKRDVFRLIIFDAFLAAMYAGYTLLLPYDVDHYYNGDEKLYSYVLTLVAVGGMLGGLSLVLNKHQPRIKTNYQDAFILAIVLILTGIWINYGLLLVSAFAYGFYTSRMSIRMMTIVQNLTDIAFLGRVFSIWFLCFDSMHPLGSFVFGFISDWFNHGTFFVLGGLVLLGLLVVYLMGRNSD
>NZ_CP012294.1|WP_046871526.1|1659160_1659541_+|iron-sulfur-cluster-biosynthesis-family-protein
MNIKFDSVSADKVQAHLDDNKRLLLTFEDGVGDYSQHAMIHMQVQFTINVVAKDMPTTGYNAVVHSNIGDLLIKDYSTDDLEENMSMKFNTHLGTLQLSGDGGAIDDNVGFIDFTDKNGIKNNPAR
>NZ_CP012294.1|WP_046871527.1|1658105_1658633_-|GNAT-family-N-acetyltransferase
MEKFEKYRPILTPHFTLDWLTAAKVKDIYALRHDANVAKMSDRDVDSDIQATVDYVNKIMRAIMNNDSLLWGISERKIEKFLGTFCIWNFNDSKTAAEVRFEVLPNQQNHGIMTEILQRMTEFSFNELGLEKLYAVAKQSNTPAITVLKKTGFEIDPTYPGSQNTLSFSLCATTR
>NZ_CP012294.1|WP_046871528.1|1657229_1658096_+|viroplasmin-family-protein
MAAKKKFYAVAKGKQTGIFTDWNETKPMIDGFPGAKYKGFKTEAEARQWLNDGGVISKTKPTKKVNTAQSHQANDTEIIVYTDGGSRNTGNVNGGHVKKQDKAAWAYLINVAGKQISDSQGEFGATNNRMEIMALLRALEWLVENQKQTDEISVVTDSQYVLNAIQKHWLAGWKRRGWKRGSGQPLANSELWRQLDGLLPKFSHLQFYWTKGHATNEGNVFVDHLLNQTMDKMSGGQVANKAIRASSPAQTASKLTKKAQKKSVPTSETQKSLDAIKKSLEKLEWYND
>NZ_CP012294.1|WP_046871529.1|1656905_1657088_+|hypothetical-protein
MRFGNFSNRDYRIALDTETQLFWASEKNDPSIKASGVTITEALDKLNEKTNGLVQQQYAN
>NZ_CP012294.1|WP_046871530.1|1656256_1656508_-|hypothetical-protein
MRKIFTLSIIGVVLVGLVFLTLSSCGDHKASFDTSTVGSSKQDSTYGAWWEHMWSLPDKNSSNKKNNPRKNSVTKFSNDDNKK
>NZ_CP012294.1|WP_062913362.1|1654855_1656184_+|NCS2-family-permease
MGEKIKNYFQIDQLHTTVKREILAGFTTFISMAYILFVNPSVLGASGMDKGAVFTATALASALGCFLMGILAKYPIATAPALGINAFFAYSVCIGMKIPWQTALAGVFVASLIFIVITIFKLREMIINAIPADLKYAISSGIGLFIAFIGLHDGGLIVANKSTVVGLGSLGVATTWLTIFGLILTSILMVRRVPGGIFIGMAATAILGLLTGLIKAPAQWVSTAPSLKPTFMVGVEHIGDINTVQLWVVVLTFLLVTFFDTAGTLVGLAQQAGFMKDNKMPRVGKALMSDSTAMLAGSVLGTSPVGAYVESSAGIAVGGRSGLTAVTTGVLFILGLFFSPMLAVVTSQVTAPALIIVGVLMAQSMKHIAWEKMEIAIPAFLILIGMPLTYSVSDGIALGFIMYPITMVAAKRGKEVHPIMYGLFFVFIFFLICRTVLKLSGK
>NZ_CP012294.1|WP_046871521.1|1663358_1664039_+|noncanonical-pyrimidine-nucleotidase,-YjjG-family
MKYQNLLFDVDDTLLDFHAAENQALKALFAEIKYPLTDDMVTYFRALNEHMWQRFELGQLDRQTLVNTRFTKLFAHFNETVDGIKYEQIYREFLNQGHQLEPHALELLNSLKDQFNLFIVSNGIGSVQQHRLNDSGLSTYFKHIFVSEEVGYQKPRIEFFDFIANHISGFTPKNALIIGDSLTSDIQGGANAGIDSVWFNPALQPNHSSVSPTYQIDDLLDLKEIL
>NZ_CP012294.1|WP_062913363.1|1664221_1664674_+|MarR-family-transcriptional-regulator
MEKHLVINRQIHVLANCSTRKFNESFLDDDITGKQGGVLHFLLMRAGKQKIYQRDIEEHFGIRRSSVTSLLQKLEDNGYITRESVADDARLKLIVLTPKAMAFQKSVVQGTIDFEARMLQGVSEDEIATWQKVTQQMTRNLKDKKIGSDK
>NZ_CP012294.1|WP_062913364.1|1664673_1666410_+|ABC-transporter-ATP-binding-protein
MLKRIGHSVREYKKYALISPILVAIETFIETFIPYLMSKMIDKGIIPGNLAYIEKLGVFMLIGTFISLAGGAGASWYSSKASAGFAKNLRHDLYHHIQDFSFEDVDHFSTSSIVVRLTTDIMNIQQAFQMLIRAAARAPLMLIFSITMAFTVDAQMAMVFVVSVPLMAIGLTVIIAIGRPLFKKVYQRYDGLNRVVRENLRGIRVVKTYNRAELEDKKAEKASSSIYEVFSKAERILQLNSPIMQFVMYGTLLFLAWFGAKRIVGGTMQTGQLVSLLAYAMSVLMRLNILSNVFNQMTISLASAQRIDEVLTYKSTLTNPKNPLTDVKTGEIDFDHVDFAYADDGVTRLEDINLHIKPGETIGIIGETGSGKSSLVQLIPRLYDVSHGSVKVGDQDVRDYDIRTLRDNVSMVLQQNVLFSGSIADNLRWGDEQATDEQLVQAAKLAQADDFINSLPDGYDTYIEQGGSNVSGGQKQRLTIARALLKNPKILILDDSTSAVDTHTDSLIQTAFREELPEMTKLIIAQRISSVQGADRIVVIDQGKIEAVGTHDELMNSDDLYQDIYNSQIKGGETHAKN
>NZ_CP012294.1|WP_046871518.1|1666396_1668292_+|ABC-transporter-ATP-binding-protein
MQRTRVAGRAKLDGSAWQILWRLLKYIMQKSHFALFIAFFSVIVSAGASVVGTLFIQRLIDDYITPLMKVAHPNFTPLLHMIILMGAIYLLGVIGTLLYSQLMIMTGQKLQKRIRDEMFTHMQQLPLSYFDSNDYGDVMSRYTNDVDTLRQMVEQSFPMFINALFNVVFTLTAMITLSPTLTIISLIVFALSIFIVRKLSSKSSYYFRMQQKALGNIDGYIEEMLNGQKVIKVFSHEDQAKAGFDKRNEALRQDASMANGLSTMLFPIMGNVGNILYVLIAVVGGYFAVNHITPITLGEIAAFVQLSRSFSQPIAQITMQLNSIIMGLAGAQRMFQLFDEPVEQDSGDTTLVYVTENEQHELTETSERTDKWAWKTPEKDGNVKLTPVKGHIEFKDVSFSYDGKKTVLHHISLDAKPGEKMAFVGATGAGKTTITNMLNRFYDISSGQILYDGIDIQNIQKASLRLSMGIVLQDTNLFTASIRDNIRYGRLNATDEEVVEAAKLANADSFIRNLPKGYDTVIDGSGSDLSQGQRQLLSIARAAIADPPTMIMDEATSSIDTRTEALVQSGMDNLMKGRTTFVIAHRLSTIHNSDEILVIEDGRIIEAGNHESLMQEKGEYYELYTGKTILE
>NZ_CP012294.1|WP_046871517.1|1668933_1669257_+|hypothetical-protein
MIQIPQDMTEVKVKIAQLEELGHKSNEKQVVFDAIQDNAQAILDEQLEGHYDSCTLDNDKITIYETPEKPIGSVKSQGASFEEDFRKNANNMFIYLQQEISKVINQR
>NZ_CP012294.1|WP_046871516.1|1669273_1670092_+|HAD-family-hydrolase
MSIKLIASDIDGTFLDDQHEFDRTRFQNQLDEMNRRGIHFVVASGNQYLHCTKVMTGINGDLTYVAEDGALIVEKGKMLDSSPIEPELWQKVVTSVDEQPILANAVIILSGEKAAHTNVTPQNEVWGRTGYFYENLTHASDFSTVTDEIYKVDVNWPDLADIRDKYNVLTTEFGNQLTEVMSGYSGIDIIKPHVTKAYGLVQLQRIWNVSMAETMTFGDNQNDAEMLKHAKYGYAMKNASPEAKAATSLVTPLDNNHSGVLDMIDRVLNDQI
>NZ_CP012294.1|WP_046871515.1|1670399_1671482_+|hypothetical-protein
MNGKRIKTVILATLAMLALTACRSQDQKRSSSKATTSVSRSATKVSKRKTVKTSDTTSQSSSSAKESAPKTNTMNFDQIKQGNYGSLQGTWTETGHSASKDGQAVEKGGTDTLTVSNGTITNGSTKVQKQTLTDAAGEHSLVFKTKDDVLTANLADEDVAINWMVTFYPKGTTNKYKTNNDSGKNSQNMIVVWTSNNSYTEIFAQTSTTPSVSKTANAAKTTKATKPVETGLNLAQISRNNFSSLVGTWKNTDGKTIIVTNEVKNKPTGSNVAYSKGAVVKGTDGNGHSRVITAGKVTSGYIQGGIGTFDSDAAVSAFDPLTIIPKNVKLSDADDSDSTRDRLILGGGQGGYATQAYYKE
>NZ_CP012294.1|WP_046871514.1|1671935_1672493_+|DUF5067-domain-containing-protein
MKKKNEAGTATKKRPIYKRIWFWLLVLIMIGGIGAIAGGSGNDSSENQADSKTEKQSESTADKSHKVGDEATVGKVSYKLNSVETTDERNEFEDTNPKNVVVAKYTVTNNSDEDVPVGTDLDVYGSDGKKLKSYAVSDNTLDSVASGKKADVEAAYGVDELGNIELHFSPLASFDDAVKFHTTVE
>NZ_CP012294.1|WP_062913365.1|1672686_1673079_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MRLVAYPAILDDSENKPGQYTVTFPDVPGAITDGNNLEEALYNAPEALGLVLFDEKVLPKSSSLQTIQKQNPDKIVTYISVDLDFIRRNSYKPTVKKNTRISAELAKKAENQGINFSATLTAALEEKLSN
>NZ_CP012294.1|WP_046871512.1|1673164_1673383_-|hypothetical-protein
MVIVNSPQKQDEIIKLLTDYKSDDVNFEFVKKTGMKMEFKTTADDAAAAKLAKSLIKGEKWGSVLFFQAIAG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012294_2	2.21\|1238997\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238997-1239026	30	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	210165-210194	5	0.833
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000032	Agrobacterium fabrum strain CFBP2788 plasmid pTi_CFBP2788, complete sequence	42590-42619	5	0.833
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	NC_019526	Enterobacteria phage vB_KleM-RaK2, complete genome	344166-344195	6	0.8
NZ_CP012294_2	2.15\|1238601\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238601-1238630	30	MN062185	Vibrio phage Phriendly, complete genome	33542-33571	6	0.8
NZ_CP012294_2	2.24\|1239195\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239195-1239224	30	AJ748296	Sulfolobus islandicus rudivirus 1 variant XX, complete genome	29266-29295	6	0.8
NZ_CP012294_2	2.24\|1239195\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239195-1239224	30	AJ414696	Sulfolobus virus SIRV-1 complete viral genome	29062-29091	6	0.8
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	MH051916	Enterobacteria phage vB_EcoM_IME340, complete genome	124535-124564	7	0.767
NZ_CP012294_2	2.10\|1238271\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238271-1238300	30	MW117965	Synechococcus phage S-H38, complete genome	72791-72820	7	0.767
NZ_CP012294_2	2.13\|1238469\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238469-1238498	30	NZ_CP024940	Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence	759517-759546	7	0.767
NZ_CP012294_2	2.19\|1238865\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238865-1238894	30	KY921761	Bacillus phage BeachBum, complete genome	15211-15240	7	0.767
NZ_CP012294_2	2.19\|1238865\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238865-1238894	30	KY821088	Bacillus phage Harambe, complete genome	15841-15870	7	0.767
NZ_CP012294_2	2.21\|1238997\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238997-1239026	30	NZ_CP025508	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvB, complete sequence	159567-159596	7	0.767
NZ_CP012294_2	2.21\|1238997\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238997-1239026	30	NZ_CP022667	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR2, complete sequence	478070-478099	7	0.767
NZ_CP012294_2	2.21\|1238997\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238997-1239026	30	NZ_CP050087	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b5, complete sequence	159584-159613	7	0.767
NZ_CP012294_2	2.21\|1238997\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238997-1239026	30	MT104465	Pseudomonas phage MR1, complete genome	18967-18996	7	0.767
NZ_CP012294_2	2.23\|1239129\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239129-1239158	30	JX195166	Pectobacterium phage My1, complete genome	24893-24922	7	0.767
NZ_CP012294_2	2.1\|1237677\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237677-1237706	30	AF191797	His2 virus, complete genome	14590-14619	8	0.733
NZ_CP012294_2	2.2\|1237743\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237743-1237772	30	NZ_CP016890	Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence	419338-419367	8	0.733
NZ_CP012294_2	2.2\|1237743\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237743-1237772	30	MN693541	Marine virus AFVG_25M436, complete genome	28757-28786	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	Y00122	Bacteriophage T4 genes nrdC, 49 and 55 (5' terminus)	1029-1058	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	KM607002	Enterobacteria phage RB55, complete genome	47527-47556	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	KJ477684	Enterobacteria phage T4 strain wild, complete genome	47549-47578	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	HM137666	Enterobacteria phage T4T, complete genome	47549-47578	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	NC_000866	Enterobacteria phage T4, complete genome	47562-47591	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	KX828711	Shigella phage SH7, complete genome	42355-42384	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	KJ477686	Enterobacteria phage T4 strain GT7, complete genome	47549-47578	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	KJ477685	Enterobacteria phage T4 strain 147, complete genome	45441-45470	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	HE956711	Yersinia phage phiD1 complete genome	44164-44193	8	0.733
NZ_CP012294_2	2.4\|1237875\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1237875-1237904	30	KM607003	Enterobacteria phage RB59, complete genome	47527-47556	8	0.733
NZ_CP012294_2	2.9\|1238205\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238205-1238234	30	NZ_CP011513	Paenibacillus peoriae strain HS311 plasmid unnamed, complete sequence	180129-180158	8	0.733
NZ_CP012294_2	2.16\|1238667\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238667-1238696	30	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	211619-211648	8	0.733
NZ_CP012294_2	2.16\|1238667\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238667-1238696	30	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	222113-222142	8	0.733
NZ_CP012294_2	2.16\|1238667\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238667-1238696	30	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	212947-212976	8	0.733
NZ_CP012294_2	2.16\|1238667\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1238667-1238696	30	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	193902-193931	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_CP021816	Sinorhizobium meliloti strain M270 plasmid accessoryB, complete sequence	11235-11264	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000043	Agrobacterium rhizogenes strain CFBP1905 plasmid pTi_CFBP1905, complete sequence	124390-124419	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_CP039694	Agrobacterium larrymoorei strain CFBP5473 plasmid pTiCFBP5473, complete sequence	209958-209987	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_CP032929	Agrobacterium tumefaciens strain 1D1460 plasmid pTi1D1460, complete sequence	190118-190147	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NC_002147	Agrobacterium tumefaciens MAFF301001 plasmid pTi-SAKURA, complete sequence	200691-200720	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NC_003065	Agrobacterium fabrum str. C58 plasmid Ti, complete sequence	28477-28506	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_MK439386	Agrobacterium tumefaciens strain T37 plasmid pTiT37, complete sequence	27057-27086	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_MK439385	Agrobacterium tumefaciens strain Kerr27 plasmid pTiKerr27, complete sequence	28477-28506	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000041	Agrobacterium tumefaciens strain CFBP296 plasmid pTi_CFBP296, complete sequence	48842-48871	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000044	Agrobacterium fabrum strain CFBP1933 plasmid pTi_CFBP1933, complete sequence	186807-186836	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000050	Agrobacterium tumefaciens strain CFBP4442 plasmid pTi_CFBP4442, complete sequence	129137-129166	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000057	Agrobacterium fabrum strain CFBP5505 plasmid pTi_CFBP5505, complete sequence	26782-26811	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000047	Agrobacterium genomosp. 1 strain CFBP2516 plasmid pTi_CFBP2516, complete sequence	115206-115235	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000046	Agrobacterium genomosp. 1 strain CFBP2177 plasmid pTi_CFBP2177, complete sequence	38214-38243	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NZ_KY000051	Agrobacterium genomosp. 1 strain CFBP5503 plasmid pTi_CFBP5503, complete sequence	46841-46870	8	0.733
NZ_CP012294_2	2.22\|1239063\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239063-1239092	30	NC_048793	Gordonia phage Kenosha, complete genome	18226-18255	8	0.733
NZ_CP012294_2	2.28\|1239460\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239460-1239489	30	NZ_MK439959	Escherichia coli strain Ec-2Lar plasmid pC-Ec2-KPC, complete sequence	47279-47308	8	0.733
NZ_CP012294_2	2.28\|1239460\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239460-1239489	30	NC_015283	Prochlorococcus phage P-RSM4, complete genome	97956-97985	8	0.733
NZ_CP012294_2	2.28\|1239460\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239460-1239489	30	AB711120	Bacillus phage PM1 DNA, complete genome	40725-40754	8	0.733
NZ_CP012294_2	2.34\|1239856\|30\|NZ_CP012294\|CRISPRCasFinder,CRT	1239856-1239885	30	CP046512	Bacillus cereus strain JHU plasmid p1, complete sequence	129098-129127	8	0.733
NZ_CP012294_2	2.23\|1239129\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239129-1239158	30	NZ_CP053715	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed8, complete sequence	20278-20307	9	0.7
NZ_CP012294_2	2.30\|1239592\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239592-1239621	30	NZ_CP015585	Roseomonas gilardii strain U14-5 plasmid 1, complete sequence	150008-150037	9	0.7
NZ_CP012294_2	2.33\|1239790\|30\|NZ_CP012294\|PILER-CR,CRISPRCasFinder,CRT	1239790-1239819	30	MN694366	Marine virus AFVG_250M1050, complete genome	29824-29853	9	0.7

1. spacer 2.21|1238997|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 5, identity: 0.833

tcatctcctccgattgcatc---tgtatctagt	CRISPR spacer
tcatctcctcctattgcatctagtgcatct---	Protospacer
*********** ********   **.****

2. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000032 (Agrobacterium fabrum strain CFBP2788 plasmid pTi_CFBP2788, complete sequence) position: , mismatch: 5, identity: 0.833

--tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtgccg--cttgccgaggccccaaccagctg	Protospacer
  *****   ********.************

3. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NC_019526 (Enterobacteria phage vB_KleM-RaK2, complete genome) position: , mismatch: 6, identity: 0.8

-tattatatgcagatcctaatgttgaactaa	CRISPR spacer
atgcta-atgcagatcctaatgttaaacttc	Protospacer
 *..** *****************.****

4. spacer 2.15|1238601|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to MN062185 (Vibrio phage Phriendly, complete genome) position: , mismatch: 6, identity: 0.8

attcgactatcccggattgattggagattc	CRISPR spacer
attaggtattcccggattggttggagattc	Protospacer
*** *..  **********.**********

5. spacer 2.24|1239195|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to AJ748296 (Sulfolobus islandicus rudivirus 1 variant XX, complete genome) position: , mismatch: 6, identity: 0.8

ttcgctttctgttgaatagtaatatgtgtt	CRISPR spacer
atcgctttctgtcgaaaagtaatattgatt	Protospacer
 ***********.*** ********  .**

6. spacer 2.24|1239195|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to AJ414696 (Sulfolobus virus SIRV-1 complete viral genome) position: , mismatch: 6, identity: 0.8

ttcgctttctgttgaatagtaatatgtgtt	CRISPR spacer
atcgctttctgtcgaaaagtaatattgatt	Protospacer
 ***********.*** ********  .**

7. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to MH051916 (Enterobacteria phage vB_EcoM_IME340, complete genome) position: , mismatch: 7, identity: 0.767

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactag	Protospacer
 .*  ******* ***** **********.

8. spacer 2.10|1238271|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to MW117965 (Synechococcus phage S-H38, complete genome) position: , mismatch: 7, identity: 0.767

aaaagtttgtgctgccaatggcaggaacgt	CRISPR spacer
gcaagtttatgatgccaatggcaggatgtt	Protospacer
. ******.** **************   *

9. spacer 2.13|1238469|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024940 (Paraburkholderia hospita strain mHSR1 plasmid pmHSR1_P, complete sequence) position: , mismatch: 7, identity: 0.767

tactcaatcgcaaattgattccgcaccaga	CRISPR spacer
gaacgaatcgcaaatggattcctcaccagg	Protospacer
 * . ********** ****** ******.

10. spacer 2.19|1238865|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to KY921761 (Bacillus phage BeachBum, complete genome) position: , mismatch: 7, identity: 0.767

aaaacgttgattgataacggtgtagcagat	CRISPR spacer
acaggtgtgattgttaacggtgtaacagat	Protospacer
* *.   ****** **********.*****

11. spacer 2.19|1238865|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to KY821088 (Bacillus phage Harambe, complete genome) position: , mismatch: 7, identity: 0.767

aaaacgttgattgataacggtgtagcagat	CRISPR spacer
acaggtgtgattgttaacggtgtaacagat	Protospacer
* *.   ****** **********.*****

12. spacer 2.21|1238997|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025508 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvB, complete sequence) position: , mismatch: 7, identity: 0.767

tcatctcctccgattgcatctgtatctagt-	CRISPR spacer
ccatctcctccgattgcaactg-gtcgggcg	Protospacer
.***************** *** .** .*.

13. spacer 2.21|1238997|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022667 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR2, complete sequence) position: , mismatch: 7, identity: 0.767

tcatctcctccgattgcatctgtatctagt-	CRISPR spacer
ccatctcctccgattgcaactg-gtcgggcg	Protospacer
.***************** *** .** .*.

14. spacer 2.21|1238997|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050087 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b5, complete sequence) position: , mismatch: 7, identity: 0.767

tcatctcctccgattgcatctgtatctagt-	CRISPR spacer
ccatctcctccgattgcaactg-gtcgggcg	Protospacer
.***************** *** .** .*.

15. spacer 2.21|1238997|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to MT104465 (Pseudomonas phage MR1, complete genome) position: , mismatch: 7, identity: 0.767

tcatctcctccgattgcatctgtatctagt	CRISPR spacer
gcatctcctgcgattgcatctgagccttct	Protospacer
 ******** ************ ..**  *

16. spacer 2.23|1239129|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to JX195166 (Pectobacterium phage My1, complete genome) position: , mismatch: 7, identity: 0.767

ttagcttatgccaacattggtggtaatgat	CRISPR spacer
gacgtttatgctaacattggtcgtaatggt	Protospacer
   *.******.********* ******.*

17. spacer 2.1|1237677|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to AF191797 (His2 virus, complete genome) position: , mismatch: 8, identity: 0.733

aggtatcgtttgtaatcctacgagtgcaat	CRISPR spacer
cgcaatcgtttgtaatcctacgaatgtctg	Protospacer
 *  *******************.**.

18. spacer 2.2|1237743|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016890 (Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

gtgataccagtgccgtttaacgctgacatc	CRISPR spacer
gactatctggtgccggttaacgctgacatc	Protospacer
*     *..****** **************

19. spacer 2.2|1237743|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to MN693541 (Marine virus AFVG_25M436, complete genome) position: , mismatch: 8, identity: 0.733

gtgataccagtgccgtttaacgctgacatc	CRISPR spacer
ccaataccagtgccgtataccgctgagtta	Protospacer
 ..************* ** ******  *

20. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to Y00122 (Bacteriophage T4 genes nrdC, 49 and 55 (5' terminus)) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

21. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to KM607002 (Enterobacteria phage RB55, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

22. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to KJ477684 (Enterobacteria phage T4 strain wild, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

23. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to HM137666 (Enterobacteria phage T4T, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

24. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NC_000866 (Enterobacteria phage T4, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

25. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to KX828711 (Shigella phage SH7, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

26. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to KJ477686 (Enterobacteria phage T4 strain GT7, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

27. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to KJ477685 (Enterobacteria phage T4 strain 147, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

28. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to HE956711 (Yersinia phage phiD1 complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

29. spacer 2.4|1237875|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to KM607003 (Enterobacteria phage RB59, complete genome) position: , mismatch: 8, identity: 0.733

tattatatgcagatcctaatgttgaactaa	CRISPR spacer
ggtattatgcagttcctactgttgaactgg	Protospacer
 .*  ******* ***** *********..

30. spacer 2.9|1238205|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011513 (Paenibacillus peoriae strain HS311 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtattacagggcttacattgcctacgcgg	CRISPR spacer
ggtattacagggctaacattgccctctatc	Protospacer
 ************* ********. *

31. spacer 2.16|1238667|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.733

ctcggtacgcaataaccttgccgccacgtc	CRISPR spacer
gtgtgctggcaatcaccttgccgccacgta	Protospacer
 *  *.  ***** ***************

32. spacer 2.16|1238667|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.733

ctcggtacgcaataaccttgccgccacgtc	CRISPR spacer
gtgtgctggcaatcaccttgccgccacgta	Protospacer
 *  *.  ***** ***************

33. spacer 2.16|1238667|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.733

ctcggtacgcaataaccttgccgccacgtc	CRISPR spacer
gtgtgctggcaatcaccttgccgccacgta	Protospacer
 *  *.  ***** ***************

34. spacer 2.16|1238667|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.733

ctcggtacgcaataaccttgccgccacgtc	CRISPR spacer
gtgtgctggcaatcaccttgccgccacgta	Protospacer
 *  *.  ***** ***************

35. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021816 (Sinorhizobium meliloti strain M270 plasmid accessoryB, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

36. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000043 (Agrobacterium rhizogenes strain CFBP1905 plasmid pTi_CFBP1905, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

37. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039694 (Agrobacterium larrymoorei strain CFBP5473 plasmid pTiCFBP5473, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

38. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032929 (Agrobacterium tumefaciens strain 1D1460 plasmid pTi1D1460, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

39. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NC_002147 (Agrobacterium tumefaciens MAFF301001 plasmid pTi-SAKURA, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

40. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NC_003065 (Agrobacterium fabrum str. C58 plasmid Ti, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

41. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK439386 (Agrobacterium tumefaciens strain T37 plasmid pTiT37, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

42. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK439385 (Agrobacterium tumefaciens strain Kerr27 plasmid pTiKerr27, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

43. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000041 (Agrobacterium tumefaciens strain CFBP296 plasmid pTi_CFBP296, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

44. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000044 (Agrobacterium fabrum strain CFBP1933 plasmid pTi_CFBP1933, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

45. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000050 (Agrobacterium tumefaciens strain CFBP4442 plasmid pTi_CFBP4442, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

46. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000057 (Agrobacterium fabrum strain CFBP5505 plasmid pTi_CFBP5505, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

47. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000047 (Agrobacterium genomosp. 1 strain CFBP2516 plasmid pTi_CFBP2516, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

48. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000046 (Agrobacterium genomosp. 1 strain CFBP2177 plasmid pTi_CFBP2177, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

49. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000051 (Agrobacterium genomosp. 1 strain CFBP5503 plasmid pTi_CFBP5503, complete sequence) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
cgtggcgcttgccgaggccccaaccagctg	Protospacer
.*. *   ********.************

50. spacer 2.22|1239063|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NC_048793 (Gordonia phage Kenosha, complete genome) position: , mismatch: 8, identity: 0.733

tgccgacattgccgagaccccaaccagctt	CRISPR spacer
gacctcggttgccgagtccccaaccagctc	Protospacer
 .**   .******** ************.

51. spacer 2.28|1239460|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK439959 (Escherichia coli strain Ec-2Lar plasmid pC-Ec2-KPC, complete sequence) position: , mismatch: 8, identity: 0.733

ttcacctacaattaatgtattaccctttaa	CRISPR spacer
cggaaaaacaaataatgttttaccctttaa	Protospacer
.  *   **** ****** ***********

52. spacer 2.28|1239460|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NC_015283 (Prochlorococcus phage P-RSM4, complete genome) position: , mismatch: 8, identity: 0.733

ttcacctacaattaatgtattaccctttaa	CRISPR spacer
tgttccttcaattaatgtattaccattatc	Protospacer
* . *** **************** **

53. spacer 2.28|1239460|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to AB711120 (Bacillus phage PM1 DNA, complete genome) position: , mismatch: 8, identity: 0.733

ttcacctacaattaatgtattaccctttaa	CRISPR spacer
ttcatctacaattaatgtatttctcgcagc	Protospacer
****.**************** *.* . .

54. spacer 2.34|1239856|30|NZ_CP012294|CRISPRCasFinder,CRT matches to CP046512 (Bacillus cereus strain JHU plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

taatgtaaaaaagcttgactgtatacacat	CRISPR spacer
taatgtaaaaaagctggactatatgagagg	Protospacer
*************** ****.***. . .

55. spacer 2.23|1239129|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053715 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed8, complete sequence) position: , mismatch: 9, identity: 0.7

ttagcttatgccaacattggtggtaatgat	CRISPR spacer
gccgcttatgccagcattggtggtctgcac	Protospacer
 . **********.**********    *.

56. spacer 2.30|1239592|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015585 (Roseomonas gilardii strain U14-5 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.7

cggggtcgcttccacatatcctgtggtcca	CRISPR spacer
gcaaaacgcttccccatatcctgcggtccg	Protospacer
  ... ******* *********.*****.

57. spacer 2.33|1239790|30|NZ_CP012294|PILER-CR,CRISPRCasFinder,CRT matches to MN694366 (Marine virus AFVG_250M1050, complete genome) position: , mismatch: 9, identity: 0.7

gtgtggcgttggctaacgttgttgagggca	CRISPR spacer
ctgtggcattggctgacgttgttgctaatt	Protospacer
 ******.******.*********  ...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

198026 : 241260

Streptococcus_phage(30.77%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_056986369.1\|198026_200270_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.3e-122	39.9
WP_046871847.1\|200366_202499_-	LTA synthase family protein	W6LM83	Streptococcus_phage	2.7e-146	45.4
WP_046871848.1\|202732_204310_-	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	3.7e-31	26.3
WP_046871849.1\|206356_207196_-	hypothetical protein	NA	NA	NA	NA
WP_062913088.1\|207545_208775_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	1.5e-80	48.4
WP_062913089.1\|208998_209409_-	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	2.8e-15	40.0
WP_056986464.1\|209518_210625_-	AI-2E family transporter	NA	NA	NA	NA
WP_046872086.1\|210928_211486_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_046872291.1\|211640_213008_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_052694544.1\|213192_214392_-	serine hydrolase	NA	NA	NA	NA
WP_062913090.1\|214415_215237_-	recombination regulator RecX	NA	NA	NA	NA
WP_046872084.1\|215493_215955_+	flavodoxin	NA	NA	NA	NA
WP_046872083.1\|215985_216405_-	GtrA family protein	NA	NA	NA	NA
WP_046872082.1\|216411_217536_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A0N9R0B2	Chrysochromulina_ericina_virus	1.4e-24	27.2
WP_056986623.1\|217841_219218_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_081113847.1\|219444_220824_-	purine permease	NA	NA	NA	NA
WP_046872508.1\|221077_221311_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_056986291.1\|221416_223288_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.6e-102	35.6
WP_046872509.1\|223709_223940_-	hypothetical protein	NA	NA	NA	NA
WP_158510929.1\|223936_224857_-	DegV family EDD domain-containing protein	A0A0N9SI50	Staphylococcus_phage	6.1e-10	32.8
WP_046872511.1\|225221_226877_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_046872513.1\|227491_227947_-	hypothetical protein	NA	NA	NA	NA
WP_046872383.1\|228162_228705_+	VanZ family protein	NA	NA	NA	NA
WP_141306346.1\|228794_229283_+	VanZ family protein	NA	NA	NA	NA
WP_062913092.1\|229421_230903_-	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_046872381.1\|231038_232076_-	LCP family protein	NA	NA	NA	NA
WP_062913093.1\|232207_233056_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	8.9e-32	36.6
WP_046872379.1\|233120_234158_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.8e-63	40.0
WP_192868929.1\|234162_234735_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D7XFA9	Escherichia_phage	8.3e-34	42.6
WP_062913094.1\|234743_235616_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.1e-100	60.1
WP_046872376.1\|235756_236908_-	glycosyltransferase	NA	NA	NA	NA
WP_010492178.1\|237364_238540_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_062913095.1\|238604_239111_-	CatB-related O-acetyltransferase	M1HKK6	Paramecium_bursaria_Chlorella_virus	4.3e-18	38.6
WP_158510930.1\|239112_239793_-	hypothetical protein	NA	NA	NA	NA
WP_046872291.1\|239892_241260_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

480308 : 531908

Streptococcus_phage(50.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062904288.1\|480308_481514_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.6e-90	45.3
WP_046872562.1\|482058_482613_+	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_046872561.1\|482666_483575_+	proline-specific peptidase family protein	NA	NA	NA	NA
WP_046872560.1\|483639_485187_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2H4UUX5	Bodo_saltans_virus	1.2e-42	28.4
WP_046872559.1\|485328_485706_+	VOC family protein	NA	NA	NA	NA
WP_046872217.1\|485765_487013_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	4.0e-105	52.7
WP_046872218.1\|487009_487840_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.4e-42	40.6
WP_046870732.1\|488012_488828_-	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_046870733.1\|488899_489775_-	DegV family protein	NA	NA	NA	NA
WP_046870734.1\|489779_490100_-	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	1.2e-21	42.7
WP_081113877.1\|490244_490904_-	TerC family protein	A0A068EP98	Bacillus_phage	4.6e-36	47.0
WP_062904067.1\|491147_492068_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_046870736.1\|492211_494887_+	MMPL family transporter	NA	NA	NA	NA
WP_046870737.1\|495571_496336_-	YibE/F family protein	NA	NA	NA	NA
WP_100077854.1\|496332_497451_-	YibE/F family protein	NA	NA	NA	NA
WP_046870739.1\|497495_497924_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046870740.1\|498112_500272_+	LTA synthase family protein	W6LM83	Streptococcus_phage	5.0e-172	48.1
WP_046870741.1\|500349_501333_-	NAD(P)/FAD-dependent oxidoreductase	A0A2K9L162	Tupanvirus	1.3e-15	25.2
WP_046870742.1\|501335_501779_-	hypothetical protein	NA	NA	NA	NA
WP_046870743.1\|501836_502310_-	NUDIX domain-containing protein	D0R7J3	Paenibacillus_phage	1.0e-13	36.6
WP_046870744.1\|502609_503569_+	nucleoside hydrolase	NA	NA	NA	NA
WP_062913141.1\|503714_505712_+	sodium:proton antiporter	NA	NA	NA	NA
WP_046870746.1\|505777_506713_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_062913142.1\|506979_507405_+	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	4.9e-07	38.9
WP_046870748.1\|507445_508297_+	hypothetical protein	NA	NA	NA	NA
WP_062913143.1\|508790_510167_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_046870749.1\|510484_511258_+	hypothetical protein	NA	NA	NA	NA
WP_010620873.1\|511479_512652_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_062913144.1\|513139_513766_+	VTT domain-containing protein	NA	NA	NA	NA
WP_046870751.1\|514010_514655_-	L,D-transpeptidase	NA	NA	NA	NA
WP_046870752.1\|514663_515122_-	hypothetical protein	NA	NA	NA	NA
WP_046870754.1\|515888_516347_+	universal stress protein	NA	NA	NA	NA
WP_046870755.1\|516418_517303_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_062904063.1\|517334_518081_+	NADPH-dependent oxidoreductase	NA	NA	NA	NA
WP_056986599.1\|518185_520552_-	phosphoketolase family protein	NA	NA	NA	NA
WP_046872328.1\|520788_521511_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_062913145.1\|521699_523067_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_080945589.1\|523191_523695_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_046872418.1\|523824_525354_-	accessory Sec system glycosyltransferase Asp1	NA	NA	NA	NA
WP_046872419.1\|525354_526914_-	glycosyltransferase	NA	NA	NA	NA
WP_062913143.1\|527234_528611_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_062913146.1\|528792_530193_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_056986623.1\|530531_531908_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

778094 : 785697

Enterococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062913189.1\|778094_779882_-	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	6.0e-54	43.3
WP_046871055.1\|780072_780591_-	nucleoside deaminase	A0A0B5J096	Pandoravirus	5.1e-06	39.7
WP_056986262.1\|780580_781204_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_046871054.1\|781504_781735_+	redoxin NrdH	X2KRY7	Enterococcus_phage	1.2e-12	44.0
WP_046871053.1\|781844_784010_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	8.6e-257	60.9
WP_046871069.1\|784035_785055_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.8e-111	60.4
WP_052694474.1\|785118_785697_+	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	3.4e-19	35.7

DBSCAN-SWA_4

837219 : 885107

Staphylococcus_phage(30.0%)

bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_056986621.1\|837219_838449_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7
WP_080945571.1\|838916_839102_-	hypothetical protein	NA	NA	NA	NA
WP_046872214.1\|839094_839787_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_062913197.1\|839803_840925_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_046872216.1\|840917_841253_-	hypothetical protein	NA	NA	NA	NA
WP_046872497.1\|841362_841578_-	hypothetical protein	NA	NA	NA	NA
WP_046872498.1\|842139_843363_+	MFS transporter	NA	NA	NA	NA
WP_056986019.1\|843392_844160_-	ABC transporter permease	NA	NA	NA	NA
WP_052694578.1\|844161_845052_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.7e-31	36.9
WP_046872521.1\|845215_845449_-	DUF2922 domain-containing protein	NA	NA	NA	NA
WP_046872520.1\|845509_845716_-	hypothetical protein	NA	NA	NA	NA
WP_155387016.1\|845898_846057_-	hypothetical protein	NA	NA	NA	NA
WP_056986621.1\|846410_847640_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7
WP_062913198.1\|848192_849026_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_046871034.1\|849018_850728_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.4e-22	34.0
WP_046871033.1\|850732_851290_-	ECF-type riboflavin transporter substrate-binding protein	NA	NA	NA	NA
WP_046871030.1\|853972_854689_+	trehalose operon repressor	NA	NA	NA	NA
WP_056986021.1\|854701_856354_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_145930482.1\|856939_857536_-	hypothetical protein	NA	NA	NA	NA
WP_062913199.1\|857757_858354_-	hypothetical protein	NA	NA	NA	NA
WP_046871043.1\|858614_859520_-	EamA family transporter	NA	NA	NA	NA
WP_062913200.1\|859698_859950_+	hypothetical protein	NA	NA	NA	NA
WP_046871025.1\|859949_860264_+	hypothetical protein	NA	NA	NA	NA
WP_046871024.1\|860504_861656_-	hypothetical protein	NA	NA	NA	NA
WP_046871023.1\|861804_864318_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	3.6e-137	31.9
WP_155386958.1\|864443_864593_-	hypothetical protein	NA	NA	NA	NA
WP_046871042.1\|864650_865055_-	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_100077967.1\|865070_865292_-	hypothetical protein	NA	NA	NA	NA
WP_155386956.1\|865651_865801_-	hypothetical protein	NA	NA	NA	NA
WP_062913453.1\|866022_867270_+\|transposase	ISL3 family transposase	A0A2H4PDF8	Mycobacterium_phage	3.5e-08	23.8
WP_046871021.1\|867388_868690_-	D-serine ammonia-lyase	NA	NA	NA	NA
WP_046871019.1\|869444_870056_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-22	32.0
WP_046871018.1\|870052_870577_-	hypothetical protein	NA	NA	NA	NA
WP_046871017.1\|870557_871364_-	hypothetical protein	NA	NA	NA	NA
WP_046871016.1\|871455_871770_-	hypothetical protein	NA	NA	NA	NA
WP_017866964.1\|872006_872264_+\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	1.0e-15	47.1
WP_145930483.1\|872248_873133_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	2.2e-65	48.3
WP_046871015.1\|873342_873858_-	hypothetical protein	NA	NA	NA	NA
WP_062913454.1\|873835_874432_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	3.1e-23	36.6
WP_046871014.1\|874485_875175_-	hypothetical protein	NA	NA	NA	NA
WP_141306314.1\|875175_875844_-	hypothetical protein	NA	NA	NA	NA
WP_046871012.1\|875827_876640_-	hypothetical protein	NA	NA	NA	NA
WP_046871011.1\|876711_877113_-	hypothetical protein	NA	NA	NA	NA
WP_046871010.1\|877165_878269_-	hypothetical protein	NA	NA	NA	NA
WP_046871009.1\|878258_878771_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_046871008.1\|879440_879668_-	hypothetical protein	NA	NA	NA	NA
WP_046871007.1\|879801_879999_-	hypothetical protein	NA	NA	NA	NA
WP_062913202.1\|879998_880781_-	hypothetical protein	NA	NA	NA	NA
WP_046871006.1\|880963_881713_-	LytTR family transcriptional regulator DNA-binding domain-containing protein	NA	NA	NA	NA
WP_062903989.1\|881713_883060_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_046871003.1\|883234_883585_-	hypothetical protein	NA	NA	NA	NA
WP_046871002.1\|883673_883862_-	hypothetical protein	NA	NA	NA	NA
WP_046871001.1\|883970_884240_-	hypothetical protein	NA	NA	NA	NA
WP_046871000.1\|884300_884564_-	hypothetical protein	NA	NA	NA	NA
WP_046870999.1\|884774_885107_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

DBSCAN-SWA_5

1407764 : 1476080

Streptococcus_phage(28.57%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062913461.1\|1407764_1408970_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.7e-89	45.0
WP_062913310.1\|1409281_1410052_+	glycosyltransferase	NA	NA	NA	NA
WP_056986064.1\|1410054_1411038_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_056986063.1\|1411302_1412508_-	CotH kinase family protein	NA	NA	NA	NA
WP_056986062.1\|1412538_1413039_-	SH3-like domain-containing protein	NA	NA	NA	NA
WP_046871591.1\|1413270_1414161_+	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_145930491.1\|1414246_1414558_+	DUF3899 domain-containing protein	NA	NA	NA	NA
WP_046871593.1\|1414610_1415417_-	sugar-phosphatase	NA	NA	NA	NA
WP_062913311.1\|1415413_1416790_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	9.6e-28	33.7
WP_046871595.1\|1417017_1417458_+	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_062903871.1\|1417503_1418088_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_062913312.1\|1418263_1419865_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	6.4e-148	50.6
WP_046871598.1\|1420098_1421379_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_046871599.1\|1421388_1422681_+	transcription termination factor Rho	NA	NA	NA	NA
WP_046871600.1\|1422789_1423047_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_100078042.1\|1423161_1424397_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_046871601.1\|1424483_1425200_+	class A sortase	NA	NA	NA	NA
WP_046871602.1\|1425244_1425712_-	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_046871603.1\|1425816_1426407_+	LemA family protein	NA	NA	NA	NA
WP_046871604.1\|1426437_1427337_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_046871605.1\|1427408_1428191_+	hypothetical protein	NA	NA	NA	NA
WP_046871606.1\|1428371_1429748_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_046871607.1\|1429925_1431488_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.3e-68	37.7
WP_046871608.1\|1431780_1432140_+	holo-ACP synthase	NA	NA	NA	NA
WP_046871609.1\|1432146_1433274_+	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	1.8e-35	31.5
WP_141306217.1\|1433351_1433624_+	hypothetical protein	NA	NA	NA	NA
WP_062913313.1\|1433642_1434014_+	type II toxin-antitoxin system PemK/MazF family toxin	A0A291I9M9	Lactobacillus_phage	2.2e-11	37.9
WP_046871612.1\|1434098_1434464_+	DUF488 family protein	NA	NA	NA	NA
WP_062913314.1\|1434460_1434949_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_046871614.1\|1435043_1435553_+	QueT transporter family protein	E7DN70	Pneumococcus_phage	2.2e-09	32.7
WP_046871615.1\|1435930_1436578_-	CBS domain-containing protein	NA	NA	NA	NA
WP_062913143.1\|1436911_1438288_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_046871616.1\|1438442_1439834_-	peptidoglycan binding domain-containing protein	NA	NA	NA	NA
WP_062913315.1\|1440017_1440980_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_046871618.1\|1441307_1441865_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_056986621.1\|1442010_1443240_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7
WP_046871619.1\|1443589_1447096_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_081113880.1\|1447142_1448708_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_046871932.1\|1449227_1449497_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_080945556.1\|1449808_1450081_+	septum formation initiator family protein	NA	NA	NA	NA
WP_046871931.1\|1450237_1450729_+	RNA-binding protein S1	NA	NA	NA	NA
WP_062913317.1\|1450811_1452209_+\|tRNA	tRNA lysidine(34) synthetase TilS	A0A0N7G7K4	Chrysochromulina_ericina_virus	1.4e-10	28.7
WP_046871930.1\|1452208_1452751_+	hypoxanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_046871929.1\|1452847_1455025_+\|protease	ATP-dependent zinc metalloprotease FtsH	I3UL75	Ostreococcus_lucimarinus_virus	1.5e-104	48.8
WP_046871928.1\|1455147_1456032_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_062913318.1\|1456165_1457173_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_046871926.1\|1457246_1458740_+\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	4.3e-90	37.7
WP_046872061.1\|1464666_1466166_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.3e-70	36.2
WP_056986386.1\|1466298_1467120_+	metallophosphoesterase	NA	NA	NA	NA
WP_062913319.1\|1467596_1468460_-	SH3-like domain-containing protein	NA	NA	NA	NA
WP_062913320.1\|1468963_1470469_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
WP_080945560.1\|1470488_1471799_-	aspartate kinase	NA	NA	NA	NA
WP_046872056.1\|1473886_1474684_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	4.4e-33	35.3
WP_062913321.1\|1474874_1476080_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	7.0e-75	46.9

DBSCAN-SWA_6

1564336 : 1624808

Streptococcus_phage(42.86%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046872291.1\|1564336_1565704_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_081113866.1\|1565707_1568224_+	alpha-mannosidase	NA	NA	NA	NA
WP_046872466.1\|1570504_1571524_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_046872468.1\|1572155_1573079_+	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_046872469.1\|1573146_1574412_+	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
WP_062913343.1\|1574404_1575361_+	hypothetical protein	NA	NA	NA	NA
WP_062904541.1\|1575451_1575793_+	hypothetical protein	NA	NA	NA	NA
WP_062904288.1\|1576511_1577717_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.6e-90	45.3
WP_046871935.1\|1578305_1579184_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_046871936.1\|1579228_1579633_-	HicB family protein	A0A1L2JY34	Aeribacillus_phage	1.7e-09	29.6
WP_046871937.1\|1579651_1579840_-	PspC domain-containing protein	NA	NA	NA	NA
WP_046871938.1\|1580100_1581729_+	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_062913344.1\|1581812_1583195_+	class II fumarate hydratase	NA	NA	NA	NA
WP_062913345.1\|1583264_1584230_+	AEC family transporter	NA	NA	NA	NA
WP_046871941.1\|1584712_1585561_+	DUF72 domain-containing protein	NA	NA	NA	NA
WP_046871942.1\|1585894_1587925_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	2.6e-90	36.7
WP_056986091.1\|1588232_1589018_+	TatD family hydrolase	NA	NA	NA	NA
WP_062913346.1\|1589004_1589556_+	ribonuclease M5	NA	NA	NA	NA
WP_046871946.1\|1589570_1590446_+	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_062913347.1\|1590888_1591449_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_046871948.1\|1591628_1593062_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_046871949.1\|1593067_1593814_+	DUF4811 domain-containing protein	NA	NA	NA	NA
WP_046871950.1\|1593885_1594197_-	DUF2316 family protein	NA	NA	NA	NA
WP_046871951.1\|1594215_1595217_-	amidohydrolase	NA	NA	NA	NA
WP_046871952.1\|1595514_1595754_+	Veg family protein	NA	NA	NA	NA
WP_056986094.1\|1596004_1596859_+	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_046871955.1\|1597218_1597467_-	hypothetical protein	NA	NA	NA	NA
WP_046871956.1\|1597505_1598168_-	hemolysin III family protein	NA	NA	NA	NA
WP_046871957.1\|1598388_1598901_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_046872318.1\|1599106_1599592_+	hypothetical protein	NA	NA	NA	NA
WP_046872317.1\|1599752_1600325_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_046872316.1\|1600412_1600877_+	universal stress protein	NA	NA	NA	NA
WP_046872291.1\|1601048_1602416_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_046872315.1\|1602548_1602785_+	hypothetical protein	NA	NA	NA	NA
WP_046872314.1\|1602948_1603398_+	universal stress protein	NA	NA	NA	NA
WP_062913348.1\|1603481_1605017_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_046872291.1\|1605320_1606688_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_062913349.1\|1607076_1608585_+	ABC-F type ribosomal protection protein	M1H3A1	Paramecium_bursaria_Chlorella_virus	9.6e-13	28.0
WP_046872308.1\|1608710_1609022_+	hypothetical protein	NA	NA	NA	NA
WP_155387000.1\|1609074_1609251_-	hypothetical protein	NA	NA	NA	NA
WP_046872307.1\|1609263_1610619_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_062913350.1\|1610860_1612171_-\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	2.9e-138	55.8
WP_046872306.1\|1612349_1613723_-	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	7.1e-31	25.8
WP_046872305.1\|1613919_1614633_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_046872304.1\|1614688_1615390_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_046872302.1\|1615774_1616089_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_046872301.1\|1616263_1616641_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_046872300.1\|1616716_1618168_+	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_062913352.1\|1618286_1619051_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_046872297.1\|1620900_1621362_+	hypothetical protein	NA	NA	NA	NA
WP_046872296.1\|1621380_1622466_+	DUF871 domain-containing protein	NA	NA	NA	NA
WP_052694556.1\|1622869_1623469_+	hypothetical protein	NA	NA	NA	NA
WP_056986621.1\|1623578_1624808_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.7e-81	48.7

DBSCAN-SWA_7

2017791 : 2027698

Staphylococcus_phage(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_056986001.1\|2017791_2019222_-	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	7.2e-26	32.8
WP_046871118.1\|2019233_2019464_-	YozE family protein	NA	NA	NA	NA
WP_046871117.1\|2019474_2020080_-	YpmS family protein	NA	NA	NA	NA
WP_046871116.1\|2020085_2021024_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_062913427.1\|2021128_2021974_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	1.2e-15	33.6
WP_046871114.1\|2022043_2022559_-	dihydrofolate reductase	S5M436	Bacillus_phage	3.5e-23	42.8
WP_046871113.1\|2022577_2023528_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	5.0e-116	62.4
WP_046871112.1\|2023546_2025448_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.8e-53	30.5
WP_046871111.1\|2025454_2026678_-\|tRNA	CCA tRNA nucleotidyltransferase	G3MAR3	Bacillus_virus	7.7e-37	43.0
WP_046871138.1\|2026822_2027698_+	YitT family protein	M1Q1P6	Streptococcus_phage	1.3e-54	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP012296

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 10394

Streptococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062913477.1\|622_1834_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_010492182.1\|1866_2238_+	DUF488 family protein	NA	NA	NA	NA
WP_062913478.1\|2418_3597_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_162492793.1\|3673_3892_+	hypothetical protein	NA	NA	NA	NA
WP_024047499.1\|4116_4878_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_010492191.1\|4886_5534_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	1.4e-50	52.4
WP_002823325.1\|5710_5974_+\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	1.2e-08	37.6
WP_003625288.1\|6265_6544_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_050340497.1\|6533_6836_+	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_062913480.1\|7308_8619_-\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	7.8e-128	54.1
WP_062913481.1\|9155_10394_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.6e-40	29.9

DBSCAN-SWA_2

13946 : 14762

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062913486.1\|13946_14762_+	alpha/beta hydrolase	A0A1I9SAY0	Mycobacterium_phage	3.0e-05	28.8

DBSCAN-SWA_3

18892 : 19603

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062913493.1\|18892_19603_-	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	3.0e-17	27.6

DBSCAN-SWA_4

28680 : 34935

Streptococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062913500.1\|28680_29649_-	replication initiator protein A	M1PFC4	Streptococcus_phage	4.0e-12	38.5
WP_062913501.1\|29841_31233_+	amino acid permease	NA	NA	NA	NA
WP_041142899.1\|31498_31681_+	hypothetical protein	A0A2P0ZLG6	Lactobacillus_phage	1.9e-08	70.2
WP_020923847.1\|31881_32160_-	BRCT domain-containing protein	NA	NA	NA	NA
WP_062913502.1\|33019_33820_+	ParA family protein	F0PIG8	Enterococcus_phage	8.0e-67	50.2
WP_062913503.1\|33821_34169_+	hypothetical protein	NA	NA	NA	NA
WP_062913504.1\|34260_34935_+	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	2.8e-28	32.9

DBSCAN-SWA_5

38347 : 38935

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062913505.1\|38347_38935_-	recombinase family protein	M4QQC6	Vibrio_phage	5.9e-19	42.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP012294

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP012296

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection