CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP015072	Escherichia coli strain Ecol_743 plasmid pEC743_3, complete sequence	0 crisprs	RT	0	0
NZ_CP015073	Escherichia coli strain Ecol_743 plasmid pEC743_4, complete sequence	0 crisprs	NA	0	0
NZ_CP015069	Escherichia coli strain Ecol_743 chromosome, complete genome	2 crisprs	cas3,DEDDh,DinG,c2c9_V-U4,csa3,RT	1	6
NZ_CP015071	Escherichia coli strain Ecol_743 plasmid pEC743_OXA48, complete sequence	0 crisprs	NA	0	1
NZ_CP015070	Escherichia coli strain Ecol_743 plasmid pEC743_1, complete sequence	0 crisprs	RT	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015069_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015069_1

4397733-4397874

Orphan

Consensus_repeat	Method
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015069_1

>merge|NZ_CP015069|1|4397733-4397874|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAGAAACCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAAACAGCGCCGGATGCGGCGTGAATGCCTTATCCGGCCTACAAAAGAAATGCAG

>NZ_CP015069|1|1|4397733-4397874|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAG	AAACCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAAACAGC
GCCGGATGCGGCGTGAATGCCTTATCCGGCCTACAAAAGAAATGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015069.1\|WP_000399432.1\|4388395_4389592_+\|UxaA-family-hydrolase	unknown	unknown	gnl\|CDD\|377287
NZ_CP015069.1\|WP_000099866.1\|4400863_4402081_+\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	unknown	unknown	gnl\|CDD\|235571
NZ_CP015069.1\|WP_001235263.1\|4396969_4397686_+\|succinate-dehydrogenase-iron-sulfur-subunit-SdhB	unknown	unknown	gnl\|CDD\|235652
NZ_CP015069.1\|WP_000126143.1\|4391108_4392419_+\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NZ_CP015069.1\|WP_000509910.1\|4404313_4405036_-\|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR	unknown	unknown	gnl\|CDD\|182065
NZ_CP015069.1\|WP_000263355.1\|4394442_4394847_+\|succinate-dehydrogenase-cytochrome-b556-subunit	unknown	unknown	gnl\|CDD\|181900
NZ_CP015069.1\|WP_001181475.1\|4398047_4400849_+\|2-oxoglutarate-dehydrogenase-E1-component	unknown	unknown	gnl\|CDD\|236499
NZ_CP015069.1\|WP_000785832.1\|4392465_4393749_-\|citrate-(Si)-synthase	unknown	unknown	gnl\|CDD\|180164
NZ_CP015069.1\|WP_000884361.1\|4412705_4414274_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|185052
NZ_CP015069.1\|WP_000648958.1\|4407138_4409772_+\|mannosylglycerate-hydrolase	unknown	unknown	gnl\|CDD\|182093
NZ_CP015069.1\|WP_000025458.1\|4403340_4404210_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NZ_CP015069.1\|WP_000568275.1\|4414289_4415429_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|184965
NZ_CP015069.1\|WP_001237779.1\|4390647_4391109_+\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NZ_CP015069.1\|WP_000254365.1\|4394840_4395188_+\|succinate-dehydrogenase-membrane-anchor-subunit	unknown	unknown	gnl\|CDD\|181901
NZ_CP015069.1\|WP_000775540.1\|4395187_4396954_+\|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|181594
NZ_CP015069.1\|WP_000735581.1\|4389619_4390588_+\|TRAP-transporter-substrate-binding-protein-DctP	unknown	unknown	gnl\|CDD\|270387
NZ_CP015069.1\|WP_001305582.1\|4393954_4394062_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015069.1\|WP_001048602.1\|4402174_4403341_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NZ_CP015069.1\|WP_001531490.1\|4405204_4407121_+\|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|182066
NZ_CP015069.1\|WP_000725054.1\|4409969_4411163_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809

Protein	Function_ID	Function_description	E-value
NZ_CP015069.1\|WP_000399432.1\|4388395_4389592_+\|UxaA-family-hydrolase	gnl\|CDD\|377287	pfam04295, GD_AH_C, D-galactarate dehydratase / Altronate hydrolase, C-terminus. Family members include the C termini of D-galactarate dehydratase (EC:4.2.1.42) which is thought to catalyze the reaction D-galactarate = 5-keto-4-deoxy-D-glucarate + H2O, and altronate hydrolase (altronic acid hydratase, EC:4.2.1.7), which catalyzes D-altronate = 2-keto-2-deoxygluconate + H2O. As purified, both enzymes are catalytically inactive in the absence of added Fe2+, Mn2+, and beta-mercaptoethanol. Synergistic activation of altronate hydrolase activity is seen in the presence of both iron and manganese ions, suggesting that the enzyme may have two ion binding sites. Mn2+ appears to be part of the enzyme active centre, but the function of the single bound Fe2+ ion is unknown. The hydratase has no Fe-S core.	5.6924e-134
NZ_CP015069.1\|WP_000099866.1\|4400863_4402081_+\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	gnl\|CDD\|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	0
NZ_CP015069.1\|WP_001235263.1\|4396969_4397686_+\|succinate-dehydrogenase-iron-sulfur-subunit-SdhB	gnl\|CDD\|235652	PRK05950, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	3.48257e-167
NZ_CP015069.1\|WP_000126143.1\|4391108_4392419_+\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	2.11617e-118
NZ_CP015069.1\|WP_000509910.1\|4404313_4405036_-\|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR	gnl\|CDD\|182065	PRK09764, PRK09764, GntR family transcriptional regulator.	1.54929e-163
NZ_CP015069.1\|WP_000263355.1\|4394442_4394847_+\|succinate-dehydrogenase-cytochrome-b556-subunit	gnl\|CDD\|181900	PRK09487, sdhC, succinate dehydrogenase cytochrome b556 subunit.	3.50714e-82
NZ_CP015069.1\|WP_000785832.1\|4392465_4393749_-\|citrate-(Si)-synthase	gnl\|CDD\|180164	PRK05614, gltA, citrate synthase.	0
NZ_CP015069.1\|WP_000884361.1\|4412705_4414274_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|185052	PRK15097, PRK15097, cytochrome bd-I ubiquinol oxidase subunit CydA.	0
NZ_CP015069.1\|WP_000648958.1\|4407138_4409772_+\|mannosylglycerate-hydrolase	gnl\|CDD\|182093	PRK09819, PRK09819, mannosylglycerate hydrolase.	0
NZ_CP015069.1\|WP_000025458.1\|4403340_4404210_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NZ_CP015069.1\|WP_000568275.1\|4414289_4415429_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|184965	PRK15003, PRK15003, cytochrome d ubiquinol oxidase subunit II.	0
NZ_CP015069.1\|WP_001237779.1\|4390647_4391109_+\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	2.66483e-21
NZ_CP015069.1\|WP_000254365.1\|4394840_4395188_+\|succinate-dehydrogenase-membrane-anchor-subunit	gnl\|CDD\|181901	PRK09488, sdhD, succinate dehydrogenase membrane anchor subunit.	5.54037e-58
NZ_CP015069.1\|WP_000775540.1\|4395187_4396954_+\|succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|181594	PRK08958, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
NZ_CP015069.1\|WP_000735581.1\|4389619_4390588_+\|TRAP-transporter-substrate-binding-protein-DctP	gnl\|CDD\|270387	cd13669, PBP2_TRAP_TM0322_like, Periplasmic component of TRAP-type C4-dicarboxylate transport system TM0322 from Thermotoga maritima and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the hyperthermophilic bacterium Thermotoga maritima TRAP-type C4-dicarboxylate transport system TM0322 and its closely related proteins. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.46494e-145
NZ_CP015069.1\|WP_001181475.1\|4398047_4400849_+\|2-oxoglutarate-dehydrogenase-E1-component	gnl\|CDD\|236499	PRK09404, sucA, 2-oxoglutarate dehydrogenase E1 component; Reviewed.	0
NZ_CP015069.1\|WP_001048602.1\|4402174_4403341_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP015069.1\|WP_001531490.1\|4405204_4407121_+\|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC	gnl\|CDD\|182066	PRK09765, PRK09765, PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional.	0
NZ_CP015069.1\|WP_000725054.1\|4409969_4411163_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.01578e-17

>NZ_CP015069.1|WP_001235263.1|4396969_4397686_+|succinate-dehydrogenase-iron-sulfur-subunit-SdhB
MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKEKDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRDLVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCPSFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPKGLNPTRAIGHIKSMLLQRNA
>NZ_CP015069.1|WP_000775540.1|4395187_4396954_+|succinate-dehydrogenase-flavoprotein-subunit
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY
>NZ_CP015069.1|WP_000254365.1|4394840_4395188_+|succinate-dehydrogenase-membrane-anchor-subunit
MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELTYEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALVVYVIYGFVVVWGV
>NZ_CP015069.1|WP_000263355.1|4394442_4394847_+|succinate-dehydrogenase-cytochrome-b556-subunit
MWALFMIRNVKKQRPVNLDLQTIRFPVTAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLLAGVLVW
>NZ_CP015069.1|WP_001305582.1|4393954_4394062_-|hypothetical-protein
MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV
>NZ_CP015069.1|WP_000785832.1|4392465_4393749_-|citrate-(Si)-synthase
MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFDPGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREIAAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKMLEEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYAQRDFKSDIKK
>NZ_CP015069.1|WP_000126143.1|4391108_4392419_+|TRAP-transporter-large-permease
MTALSELLAGSWLDNWLMIIPLMFVCLFINMPVWLAMFCGILTYFLCYSNVPLMVAIQRLIATTQTPSLLAIPFFILLGTLMSYTGIAARILQIANVLIGRMRGGLGGANILVSTMMGGVSASNLADAAMLSRMMVPEMEQKGYSRGFAAAITASGSLITPIIPPGIALILYGLVADVSIGSMFMAGILPGLLCSAMLIVTVWLVAIRRGLKPSSEHWPKPKEVSVALVQAWPALFLIVAVIGGIRANIFTPTEAGAVAVLLVMFIGFVIYRELKISHVFTALSETARSTASVMLIIMASAALGWIFSLERAGITVAEFVTSLTDNKYVFLLIINLLLLVLGMFLEGSAILLILVPLLKPVVAHFGIDPVHFGIIMILNLSLGTLSPPVGTVMLLVCNTVQVSVGQFMREAVPLLISLILLLLVITYIPAISLLLV
>NZ_CP015069.1|WP_001237779.1|4390647_4391109_+|TRAP-transporter-small-permease
MRLLGKMIEVAAVLTLFILVIMTIAAVIMRYCFHMPLQWTEEVSGLLMIWVVMFGAVVAERDNTHLSIPFLADALTSRGQRILAFLVSLMSIILLVVMAWSAWKLAAGTAFKTTQILKISWFWIDIAVTVGAIGVACFTALQLIKKTPRKEGE
>NZ_CP015069.1|WP_000735581.1|4389619_4390588_+|TRAP-transporter-substrate-binding-protein-DctP
MKKLLTPLLFLLALFSPMLNAAPVTIKIAYESNPGEPADTVVKHWAELVKKKSNGDIVFELYPSSQLGSKQDITEQALMGMNIITISDVGFLTDYDADLGILFGPYLTEDPQKLFAIYASDWFKQKEQKLREKGVHIVMSNYLYGTRQIIAKKPIRTPEDLKGMKIRVPNNVMQIKAIEAMGATPTPMPLGDVYPALTQGMIDGVENPVSVLYGQKLHEQAKYLSMVNYLTNTSLWLGGEAFFSTLTPAQLDIIHQTAYEAGLYSQKITTEQDATMLKTMQEQGVEIIYPDVAPFKEKALKVYQQFPEWTPGLYDTIQQQLK
>NZ_CP015069.1|WP_000399432.1|4388395_4389592_+|UxaA-family-hydrolase
MEGYVRQNGRPGIRNTVQVIFMVECASHVAKKIAEGFPCHDVQYFGFSGCYPSDYGYRLVKNLATHSNVGGVLIISLGCENFDRRRLEQEVRESGRPCHTLVIQENKGTTNTITLGKQLVAEMLEQLADTPRCILNWSDLVVGTICGGSDGTSGITGNPAVGRAFDQLLEKGATCIFEESGELLGCEQHMMSRAASSQARDAIEVAMTKAERYYSLMGLGSFSNGNAEGGLTTQEEKSLGAYTKSGDALIAGVILPTQQTPFPGLWLMDVVPDGEPRFGYPNINDSSEALELIASGCHMVLFTTGRGSVIGSVIAPIIKVCNNPQTWEHLSDDMDVNAGRVISEGATLDDIADDIMQVIEHVANGQYCAAERLEHQEFVLTYKAFDYSKSAVCRADPR
>NZ_CP015069.1|WP_001181475.1|4398047_4400849_+|2-oxoglutarate-dehydrogenase-E1-component
MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAISEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALNVE
>NZ_CP015069.1|WP_000099866.1|4400863_4402081_+|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase
MSSVDILVPDLPESVADATVATWHKKPGDVVVRDEVLVEIETDKVVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQQASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAPAAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV
>NZ_CP015069.1|WP_001048602.1|4402174_4403341_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
>NZ_CP015069.1|WP_000025458.1|4403340_4404210_+|succinate--CoA-ligase-subunit-alpha
MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPTLDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYEAVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEAAAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRSLADIGEALKTVLK
>NZ_CP015069.1|WP_000509910.1|4404313_4405036_-|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR
MGHKPLYRQIADRIREQITCGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVETHSEVLIFEVIPADNFLQQQLQISEQDRVWHVKRVRYRKQKPVALEETWMPLALFPDLTWQVMENSKYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGQVFEYSRNAFNTDDYKFTLIAQRKSPR
>NZ_CP015069.1|WP_001531490.1|4405204_4407121_+|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC
MNLTTLTHRDALCLNVRFTSREEAIHALTQRLAALGKISSTEQFLEEVYCRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMKLLTALTTRLADDELRARIQSATTPDELLSALDDKGDAQHTASFSYAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNIYVEKQGANGIEERLTAEQLNSATACIFAAEVAIKESERFNGIPALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGGMLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGNNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLIWRHHAVKHGNYLTDGVMP
>NZ_CP015069.1|WP_000648958.1|4407138_4409772_+|mannosylglycerate-hydrolase
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKLVEGGKLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDKTEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMEKLREIYPQRKFVMSRFEEVFEQIEAQRESLAILKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFDYHHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEVINTTVRLRGSQFNLRDGRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQISQIVPSMGYRTLYIEANQPGNVVTPKSKTEGILENAFWQIALNEDGSLRLVDKDSGVRYDRVFQIEEGSDDGDEYDYSPAKEEWAITSANAKPQYDIIHEAWQSRAIIRYEIAVPRNLSERRAKQCSGRVGVETVITLSHNSRRIDADINLDNQADDHRIRVLIPTPFNTDVVLADTQFGSLTRPVKDCAMNVWQQEGWKEAPVPVWNMLNYAVLQEGRNGIAVFSEGLREFEVIGEENKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVSDSQLRGSFSCRLSLFSYIGTPVTAGVAQQARAWLTPVQCYNKIPWDAMKLNKAKFNVPESYSLLKMPPVGCLISALKKAEDRQELILRLFNPAELTSCDATVAFSRKVMTCTETMMNERFNTEKNEVLKELALFLPGQSRTFSYRIV
>NZ_CP015069.1|WP_000725054.1|4409969_4411163_+|tetratricopeptide-repeat-protein
MKKIVLPVALALLGMNAGAYAADVSIDILSATVKDKRIEGASVTLQRNGAQSVSGITNTSGSISLGTSFADNKDALLIVKKEGYSNLVVKCPCAGMTYAISPVMTNLDGMRVVLSWGEKPFDLDSHLIFPGGHIYFDSKEGTDANLDVDDTDSYGPETVTISKKHFGESYIYAVQDYSNKGLPNSNYLSASKAKVFVYVGSSLVRSYSVPAGKRGNIWTVFKLNPNGEFEDINSVTSANFNGTTLDVRDLATVIMPATDSSAPASPAMQNSGDTQLARKYNREGEAVYKTGQLEQAIQLFQQATELDGNYGQAFSNLGLAYQKNGNIAEAIWANRKAISLASGVNAATTRANSYYNIAKIYETSGQNAEALQHYQLAYTEKNKPSYEEAIARVKTKM
>NZ_CP015069.1|WP_000884361.1|4412705_4414274_+|cytochrome-ubiquinol-oxidase-subunit-I
MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSGKQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLMAFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFNFETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKRSFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPDQEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSGSTDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRIMVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQPWAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGRYHFEQSSTTTQPAR
>NZ_CP015069.1|WP_000568275.1|4414289_4415429_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDTERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPVGFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGNFFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALAGVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLPLLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQLTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY

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Crispr_ID: NZ_CP015069_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015069_2

4563941-4564023

Orphan

I-F

Consensus_repeat	Method
AGTTCACTGCCGTACAGGCAGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015069_2

>merge|NZ_CP015069|2|4563941-4564023|CRISPRCasFinder
AGTTCACTGCCGTACAGGCAGCTTAGAAATTGCCGCGGATCCTGTCTGCCAATAATGACAAGTTCACTGCCGTACAGGCAGAT

>NZ_CP015069|2|2|4563941-4564023|CRISPRCasFinder
AGTTCACTGCCGTACAGGCAGCT	TAGAAATTGCCGCGGATCCTGTCTGCCAATAATGACA
AGTTCACTGCCGTACAGGCAGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015069.1\|WP_001241674.1\|4564916_4565621_-\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NZ_CP015069.1\|WP_000067797.1\|4576298_4577642_+\|replication-associated-recombination-protein-RarA	unknown	unknown	gnl\|CDD\|237355
NZ_CP015069.1\|WP_000458841.1\|4550431_4552084_-\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NZ_CP015069.1\|WP_001295343.1\|4575676_4576288_+\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NZ_CP015069.1\|WP_000188152.1\|4558535_4560482_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NZ_CP015069.1\|WP_001385255.1\|4569273_4570239_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NZ_CP015069.1\|WP_001040187.1\|4564413_4564632_-\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NZ_CP015069.1\|WP_001351020.1\|4556316_4557273_-\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
NZ_CP015069.1\|WP_000491137.1\|4552227_4553127_-\|L-lysine-exporter-LysO	unknown	unknown	gnl\|CDD\|225287
NZ_CP015069.1\|WP_000410785.1\|4560554_4560779_-\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
NZ_CP015069.1\|WP_000934041.1\|4561452_4563729_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
NZ_CP015069.1\|WP_000886683.1\|4577732_4579025_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_CP015069.1\|WP_000520775.1\|4561101_4561422_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NZ_CP015069.1\|WP_001043561.1\|4567384_4569151_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NZ_CP015069.1\|WP_000746478.1\|4557423_4558539_+\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NZ_CP015069.1\|WP_000077084.1\|4571411_4575518_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NZ_CP015069.1\|WP_001202204.1\|4565662_4567384_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
NZ_CP015069.1\|WP_000488716.1\|4553541_4554237_-\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NZ_CP015069.1\|WP_000599803.1\|4554661_4556320_+\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NZ_CP015069.1\|WP_000228473.1\|4570782_4571277_+\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009

Protein	Function_ID	Function_description	E-value
NZ_CP015069.1\|WP_001241674.1\|4564916_4565621_-\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.92039e-139
NZ_CP015069.1\|WP_000067797.1\|4576298_4577642_+\|replication-associated-recombination-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP015069.1\|WP_000458841.1\|4550431_4552084_-\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NZ_CP015069.1\|WP_001295343.1\|4575676_4576288_+\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
NZ_CP015069.1\|WP_000188152.1\|4558535_4560482_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NZ_CP015069.1\|WP_001385255.1\|4569273_4570239_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NZ_CP015069.1\|WP_001040187.1\|4564413_4564632_-\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
NZ_CP015069.1\|WP_001351020.1\|4556316_4557273_-\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	3.43529e-131
NZ_CP015069.1\|WP_000491137.1\|4552227_4553127_-\|L-lysine-exporter-LysO	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	3.40497e-117
NZ_CP015069.1\|WP_000410785.1\|4560554_4560779_-\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
NZ_CP015069.1\|WP_000934041.1\|4561452_4563729_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NZ_CP015069.1\|WP_000886683.1\|4577732_4579025_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP015069.1\|WP_000520775.1\|4561101_4561422_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	3.7104e-49
NZ_CP015069.1\|WP_001043561.1\|4567384_4569151_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP015069.1\|WP_000746478.1\|4557423_4558539_+\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NZ_CP015069.1\|WP_000077084.1\|4571411_4575518_+\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NZ_CP015069.1\|WP_001202204.1\|4565662_4567384_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NZ_CP015069.1\|WP_000488716.1\|4553541_4554237_-\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	7.82992e-144
NZ_CP015069.1\|WP_000599803.1\|4554661_4556320_+\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NZ_CP015069.1\|WP_000228473.1\|4570782_4571277_+\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117

>NZ_CP015069.1|WP_000934041.1|4561452_4563729_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>NZ_CP015069.1|WP_000520775.1|4561101_4561422_+|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMDFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NZ_CP015069.1|WP_000410785.1|4560554_4560779_-|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>NZ_CP015069.1|WP_000188152.1|4558535_4560482_+|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLEWKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNATGGTEPVVNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>NZ_CP015069.1|WP_000746478.1|4557423_4558539_+|macrolide-transporter-subunit-MacA
MKKRKTVKKRYVIAMVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDNAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKINDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>NZ_CP015069.1|WP_001351020.1|4556316_4557273_-|DUF535-domain-containing-protein
MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFCS
>NZ_CP015069.1|WP_000599803.1|4554661_4556320_+|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENIPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>NZ_CP015069.1|WP_000488716.1|4553541_4554237_-|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRN
>NZ_CP015069.1|WP_000491137.1|4552227_4553127_-|L-lysine-exporter-LysO
MFSGLLIILVPLIVGYLIPLRQKAALRVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSTTVILLCNIAALMWLERGLPWSNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>NZ_CP015069.1|WP_000458841.1|4550431_4552084_-|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIATLQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIIGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
>NZ_CP015069.1|WP_001040187.1|4564413_4564632_-|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NZ_CP015069.1|WP_001241674.1|4564916_4565621_-|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCDEFIRHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLSNNFWVPRCLFSPQE
>NZ_CP015069.1|WP_001202204.1|4565662_4567384_-|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPKVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGIYLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>NZ_CP015069.1|WP_001043561.1|4567384_4569151_-|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLFLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQTALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGRYAELSVAGGPFATLLAHRQEEI
>NZ_CP015069.1|WP_001385255.1|4569273_4570239_-|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNTDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NZ_CP015069.1|WP_000228473.1|4570782_4571277_+|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NZ_CP015069.1|WP_000077084.1|4571411_4575518_+|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTVRGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQSTVAWQPVPGPQTGEPVIAPAPEGYPQQPQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAAEQPAQQPYYAPAPEQAVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPTRPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNTEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPVAQQPQYQQPQQPVTQQPQYQQPQQPVVPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NZ_CP015069.1|WP_001295343.1|4575676_4576288_+|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>NZ_CP015069.1|WP_000067797.1|4576298_4577642_+|replication-associated-recombination-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAVGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NZ_CP015069.1|WP_000886683.1|4577732_4579025_+|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	12111-12158	8	0.833
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	424237-424284	8	0.833
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7391-7438	10	0.792
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84215-84262	10	0.792
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87125-87172	10	0.792
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229237-229284	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229338-229385	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229439-229486	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239731-239778	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239832-239879	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239933-239980	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15006-15053	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230643-230690	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230744-230791	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230845-230892	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211613-211660	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211714-211761	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211815-211862	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_AP023207	Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence	31250-31297	11	0.771
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3371-3418	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4012-4059	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4113-4160	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208980-209027	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3370-3417	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4011-4058	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4112-4159	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219474-219521	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3370-3417	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4011-4058	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4112-4159	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210308-210355	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3370-3417	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4011-4058	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4112-4159	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191263-191310	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	MT230402	Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence	270-317	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	101195-101242	12	0.75
NZ_CP015069_1	1.1\|4397780\|48\|NZ_CP015069\|CRISPRCasFinder	4397780-4397827	48	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	158-205	13	0.729

1. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 8, identity: 0.833

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gactcgtaggcctgataagacgcgccagcgtcgcatcaggcaccgaac	Protospacer
.* .********************* ****************   *.*

2. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 8, identity: 0.833

aaaccgtaggcctgataagacgcgcaagcgtcg-catcaggcaaacagc	CRISPR spacer
aacctgtaggcctgataagacgcgcaagcgtcgccatcaggcatctca-	Protospacer
** *.**************************** *********  . .

3. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gttttgtaggcatgataagacgcgccagcgtcgcatcaggcatccggc	Protospacer
.  ..****** ************* ****************  *.**

4. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gttttgtaggcatgataagacgcgccagcgtcgcatcaggcatccggc	Protospacer
.  ..****** ************* ****************  *.**

5. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
attttgtaggcctgataagacgcggcagcgtcgcatcaggcatcgtgc	Protospacer
*  ..*******************  ****************    **

6. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

7. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

8. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

9. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

10. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

11. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

12. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctggt	Protospacer
.. .******* ************* ****************  ..*.

13. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

14. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

15. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

16. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

17. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

18. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

19. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_AP023207 (Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
cggctgtaggcctgataagacgcgacagcgtcgcatcaggcattgatt	Protospacer
 ..*.*******************  ****************   * .

20. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

21. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

22. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

23. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

24. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

25. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

26. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

27. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

28. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

29. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

30. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

31. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

32. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

33. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

34. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

35. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

36. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to MT230402 (Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggtttgtaggcctgataagacgcgacagcgtcgcatcaggcattgatt	Protospacer
.. ..*******************  ****************   * .

37. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
taatacaaggcctgataagacgcgccagcgtcgcatcaggcgctgaat	Protospacer
 **.   ****************** ***************.   *..

38. spacer 1.1|4397780|48|NZ_CP015069|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gtctngtaggcctgataagacgcgtcagcgtcgcatcaggcttcaatt	Protospacer
.  . *******************. ***************    * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

860729 : 869400

Escherichia_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000272486.1\|860729_861833_-	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	1.0e-133	59.5
WP_001393538.1\|861840_863088_-	O16 family O-antigen flippase	NA	NA	NA	NA
WP_001100981.1\|863084_863642_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	7.8e-53	57.5
WP_000783975.1\|863641_864523_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.9e-106	63.8
WP_001023617.1\|864580_865480_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	6.3e-28	34.5
WP_000699450.1\|865479_866565_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.9e-101	53.9
WP_000183060.1\|866937_867831_-	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
WP_001115960.1\|868005_869400_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	6.3e-19	31.9

DBSCAN-SWA_2

965438 : 973750

Enterobacteria_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001296230.1\|965438_967442_+	SWIM zinc finger family protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.7
WP_001296231.1\|967566_968028_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	3.2e-76	99.3
WP_001295430.1\|968068_968539_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_000598641.1\|968585_969305_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295431.1\|969301_970987_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_001240408.1\|971208_971940_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	6.3e-111	98.5
WP_001216963.1\|971999_972107_+	protein YohO	NA	NA	NA	NA
WP_000783109.1\|972087_972819_-	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_000569347.1\|972823_973750_-	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	1.3e-23	30.8

DBSCAN-SWA_3

1205573 : 1283415

Stx2-converting_phage(33.33%)

integrase,transposase

attL 1205380:1205399|attR 1281551:1281570

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1205380:1205399	attL	NA	NA	NA	NA
WP_001131472.1\|1205573_1206764_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	7.6e-130	57.3
WP_000160236.1\|1208031_1208187_+	hypothetical protein	NA	NA	NA	NA
WP_001610751.1\|1209499_1211860_-	type I restriction enzyme HsdR N-terminal domain-containing protein	NA	NA	NA	NA
WP_000100142.1\|1212503_1213520_-	hypothetical protein	NA	NA	NA	NA
WP_001610752.1\|1214001_1216200_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_000117528.1\|1216196_1217513_-	ATP-binding protein	NA	NA	NA	NA
WP_000424707.1\|1217516_1219826_-	TerB N-terminal domain-containing protein	NA	NA	NA	NA
WP_001361538.1\|1220294_1220453_+	hypothetical protein	NA	NA	NA	NA
WP_123863910.1\|1220576_1220867_+	hypothetical protein	NA	NA	NA	NA
WP_001610754.1\|1222100_1223132_+	MFS transporter	NA	NA	NA	NA
WP_000864948.1\|1224138_1225164_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_097748387.1\|1225719_1226864_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.0e-66	44.3
WP_000950719.1\|1230429_1230768_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_000186596.1\|1230761_1231049_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_001361993.1\|1231808_1232168_+	hypothetical protein	NA	NA	NA	NA
WP_000906844.1\|1232215_1232887_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_001610764.1\|1234425_1234773_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_032158436.1\|1234772_1235450_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	2.5e-21	46.0
WP_077250878.1\|1236174_1236465_-	hypothetical protein	NA	NA	NA	NA
WP_001610769.1\|1237304_1238912_+	FGGY-family carbohydrate kinase	NA	NA	NA	NA
WP_024193919.1\|1238935_1240585_+	signal transduction protein	NA	NA	NA	NA
WP_001610771.1\|1240727_1242182_+	MFS transporter	NA	NA	NA	NA
WP_001610772.1\|1242239_1243343_+	mandelate racemase/muconate lactonizing enzyme family protein	NA	NA	NA	NA
WP_001610773.1\|1243366_1244194_+	SDR family oxidoreductase	A0A167REC2	Powai_lake_megavirus	5.3e-05	29.2
WP_001610774.1\|1244187_1245093_+	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_001610775.1\|1245085_1245514_+	heme-binding protein	NA	NA	NA	NA
WP_024193920.1\|1245562_1246573_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_154675828.1\|1249282_1249450_-	hypothetical protein	NA	NA	NA	NA
WP_001610781.1\|1249794_1250220_-	hypothetical protein	NA	NA	NA	NA
WP_000270955.1\|1250216_1250600_-	hypothetical protein	NA	NA	NA	NA
WP_000860849.1\|1250971_1251571_-	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_072146520.1\|1251802_1251952_-	hemolysin activation protein	NA	NA	NA	NA
WP_001367564.1\|1253018_1253810_+	hypothetical protein	NA	NA	NA	NA
WP_001347898.1\|1254193_1254400_+	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_000782651.1\|1254487_1255096_+	hypothetical protein	NA	NA	NA	NA
WP_001339397.1\|1258456_1259134_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_001610764.1\|1259133_1259481_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001610787.1\|1259500_1261072_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.2e-167	58.1
WP_110046492.1\|1260992_1261670_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.5e-98	93.6
WP_000255956.1\|1261666_1262689_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.0e-199	99.1
WP_001493615.1\|1263713_1264649_-	hypothetical protein	NA	NA	NA	NA
WP_000998321.1\|1264645_1266958_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001610790.1\|1267262_1267865_-\|integrase	tyrosine-type recombinase/integrase	A0A1V0E036	Clostridioides_phage	1.8e-07	33.3
WP_001610792.1\|1268263_1269364_+	hypothetical protein	NA	NA	NA	NA
WP_001610793.1\|1269660_1270095_-	hypothetical protein	NA	NA	NA	NA
WP_001069762.1\|1274395_1275268_+	GTPase family protein	NA	NA	NA	NA
WP_063131951.1\|1275640_1278487_+	autotransporter adhesin Ag43	NA	NA	NA	NA
WP_001610805.1\|1278814_1279633_+	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	2.7e-46	39.3
WP_001610806.1\|1279724_1280210_+	antirestriction protein	A9J566	Pseudomonas_phage	9.0e-13	31.0
WP_001610807.1\|1280224_1280701_+	RadC family protein	NA	NA	NA	NA
WP_000691817.1\|1280763_1280985_+	DUF987 domain-containing protein	A0A142F0X9	Klebsiella_phage	1.1e-10	45.8
WP_001298859.1\|1281873_1283415_+\|transposase	IS21-like element ISEc12 family transposase	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
1281551:1281570	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1612506 : 1619646

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000103863.1\|1612506_1615068_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.6e-31	20.8
WP_001141293.1\|1615173_1615830_+	protein-serine/threonine phosphatase	A0A077SLQ6	Escherichia_phage	3.3e-50	46.1
WP_001296319.1\|1615880_1616648_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	9.7e-70	57.4
WP_000847996.1\|1616843_1617752_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	1.9e-117	76.2
WP_000590411.1\|1617748_1619011_+	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	2.2e-135	61.4
WP_001279004.1\|1619007_1619646_+	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	74.5

DBSCAN-SWA_5

1868919 : 1929790

Staphylococcus_phage(20.0%)

tRNA,transposase,protease,lysis,integrase

attL 1870128:1870145|attR 1934458:1934475

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001546095.1\|1868919_1869678_+\|protease	metalloprotease LoiP	NA	NA	NA	NA
WP_000105562.1\|1870107_1871028_-	agmatinase	NA	NA	NA	NA
1870128:1870145	attL	NA	NA	NA	NA
WP_000758881.1\|1871163_1871895_-	hypothetical protein	NA	NA	NA	NA
WP_001295380.1\|1872040_1874017_-	biosynthetic arginine decarboxylase	NA	NA	NA	NA
WP_001297406.1\|1874025_1874157_-	acid stress response protein YqgB	NA	NA	NA	NA
WP_001331575.1\|1874292_1874508_+	hypothetical protein	NA	NA	NA	NA
WP_001062128.1\|1874811_1875966_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.0e-128	63.2
WP_001112301.1\|1876402_1877797_+	galactose/proton symporter	NA	NA	NA	NA
WP_000858396.1\|1877873_1878371_+\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_001305312.1\|1878465_1879173_+	deoxyribonuclease I	NA	NA	NA	NA
WP_001531929.1\|1879252_1879984_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_000593260.1\|1879996_1880947_+	glutathione synthase	NA	NA	NA	NA
WP_001355636.1\|1881055_1881619_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_000017111.1\|1881618_1882035_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_001546096.1\|1882213_1883194_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_000997795.1\|1883211_1883916_+	pyridoxal phosphate homeostasis protein	NA	NA	NA	NA
WP_001094831.1\|1883933_1884500_+	osmotic shock tolerance protein YggT	NA	NA	NA	NA
WP_001277222.1\|1884496_1884787_+	YggU family protein	NA	NA	NA	NA
WP_001174747.1\|1884794_1885388_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_000239978.1\|1885380_1886517_+	radical SAM family heme chaperone HemW	NA	NA	NA	NA
WP_000745201.1\|1886585_1887593_-	DUF1202 family protein	NA	NA	NA	NA
WP_000394125.1\|1887709_1888756_-	L-asparaginase 2	NA	NA	NA	NA
WP_000984796.1\|1888931_1889651_-	DUF2884 domain-containing protein	NA	NA	NA	NA
WP_001107564.1\|1889834_1890161_-	YggL family protein	NA	NA	NA	NA
WP_000786911.1\|1890160_1890880_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_001376017.1\|1891040_1892093_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000091700.1\|1892120_1892396_+	oxidative damage protection protein	NA	NA	NA	NA
WP_001618095.1\|1892459_1893539_+	membrane-bound lytic murein transglycosylase MltC	NA	NA	NA	NA
WP_001327414.1\|1893740_1894997_+	nucleoside permease NupG	NA	NA	NA	NA
WP_001546097.1\|1895045_1897181_-	ornithine decarboxylase	NA	NA	NA	NA
WP_000234526.1\|1897573_1898281_+	DUF554 domain-containing protein	NA	NA	NA	NA
WP_001218869.1\|1898659_1899925_+\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	2.1e-77	38.1
WP_000147017.1\|1900180_1901224_+	hypothetical protein	NA	NA	NA	NA
WP_001774069.1\|1902917_1903469_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_001296368.1\|1905972_1906194_+	pap operon regulatory protein PapI	NA	NA	NA	NA
WP_001189123.1\|1907320_1908829_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.6e-44	31.8
WP_001513409.1\|1910331_1910445_-\|lysis	lysis protein	NA	NA	NA	NA
WP_001110186.1\|1912278_1912539_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_000109147.1\|1912580_1913141_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001296373.1\|1913180_1913609_+	DUF417 family protein	NA	NA	NA	NA
WP_149019277.1\|1914317_1915545_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	4.5e-170	95.0
WP_000074472.1\|1915658_1916852_-	MFS transporter	NA	NA	NA	NA
WP_001296374.1\|1916987_1918712_+	aerobactin synthase IucA	NA	NA	NA	NA
WP_001287500.1\|1918712_1919660_+	N(6)-hydroxylysine O-acetyltransferase	NA	NA	NA	NA
WP_001015715.1\|1919659_1921402_+	aerobactin synthase IucC	NA	NA	NA	NA
WP_000750130.1\|1921398_1922676_+	NADPH-dependent L-lysine N(6)-monooxygenase	NA	NA	NA	NA
WP_000973516.1\|1922757_1924959_+	ferric aerobactin receptor IutA	NA	NA	NA	NA
WP_011076574.1\|1925509_1925653_-	hypothetical protein	NA	NA	NA	NA
WP_001546100.1\|1925902_1929790_+\|protease	serine protease autotransporter toxin Sat	Q9LA58	Enterobacterial_phage	7.5e-227	38.8
1934458:1934475	attR	NA	NA	NA	NA

DBSCAN-SWA_6

4806521 : 4854469

Enterobacteria_phage(57.14%)

tRNA,transposase,tail,head,portal,lysis,capsid,terminase,integrase

attL 4800703:4800717|attR 4822846:4822860

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4800703:4800717	attL	NA	NA	NA	NA
WP_001295972.1\|4806521_4807628_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000476093.1\|4807681_4808143_-	phosphatase NudJ	NA	NA	NA	NA
WP_001248677.1\|4808152_4808806_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000444487.1\|4808977_4810228_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_000741335.1\|4810341_4811484_-\|integrase	phage integrase Arm DNA-binding domain-containing protein	Q77Z02	Phage_21	3.6e-206	100.0
WP_000088653.1\|4811473_4811710_-	excisionase	NA	NA	NA	NA
WP_000488406.1\|4811849_4812089_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	3.9e-38	94.9
WP_000763364.1\|4812136_4812355_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	1.8e-34	95.8
WP_001308571.1\|4812453_4812735_-	hypothetical protein	A0A0P0ZE02	Stx2-converting_phage	1.2e-46	97.8
WP_000548537.1\|4812745_4812937_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
WP_000149539.1\|4812909_4813092_-	DUF1317 domain-containing protein	A0A0N7CHV0	Escherichia_phage	6.3e-28	96.7
WP_000186858.1\|4813088_4813769_-	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	4.6e-132	99.6
WP_000100847.1\|4813765_4814551_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000995417.1\|4814556_4814853_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.5e-47	96.9
WP_000233576.1\|4814928_4815135_-	phage encoded cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
WP_000866321.1\|4815610_4815988_-	ASCH domain-containing protein	Q6SE87	Lactobacillus_prophage	1.3e-30	49.2
WP_000380252.1\|4815965_4817027_-	hypothetical protein	Q6SE88	Lactobacillus_prophage	2.9e-64	42.0
WP_000712396.1\|4817107_4817800_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	2.5e-109	85.3
WP_000184665.1\|4817910_4818138_+	helix-turn-helix domain-containing protein	Q76H55	Enterobacteria_phage	3.8e-22	69.0
WP_001182881.1\|4818168_4818708_+	hypothetical protein	M9NZI6	Enterobacteria_phage	8.9e-62	66.7
WP_000147914.1\|4818704_4819724_+	replication protein	A0A0M5M7Y1	Salmonella_phage	2.7e-112	64.7
WP_000788877.1\|4819720_4820422_+	Replication protein 14	K7P6G2	Enterobacteria_phage	9.9e-130	100.0
WP_000145918.1\|4820418_4820721_+	protein ren	A0A0N6WES4	Escherichia_phage	1.3e-41	93.5
WP_001070442.1\|4820788_4821121_+	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_032143398.1\|4821169_4821319_+	hypothetical protein	NA	NA	NA	NA
WP_000709098.1\|4821376_4822903_+	recombinase family protein	Q3HQV4	Burkholderia_phage	2.7e-31	30.8
4822846:4822860	attR	NA	NA	NA	NA
WP_000700204.1\|4823252_4824296_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_072093903.1\|4824645_4824747_+	hypothetical protein	NA	NA	NA	NA
WP_001053004.1\|4824743_4825199_+	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	1.2e-59	66.9
WP_000224907.1\|4825198_4825369_+	hypothetical protein	K7P7K0	Enterobacteria_phage	5.3e-13	67.9
WP_000774475.1\|4825361_4825652_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	1.3e-46	93.8
WP_001099697.1\|4825648_4826011_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	7.3e-60	95.7
WP_000971095.1\|4826007_4826148_+	YlcG family protein	K7PHH3	Enterobacteria_phage	1.7e-09	72.1
WP_001204794.1\|4826233_4826617_+	antitermination protein QuuD	A0A088CD47	Shigella_phage	2.0e-55	82.5
WP_000737277.1\|4826805_4827888_-	porin OmpC	Q1MVN1	Enterobacteria_phage	4.1e-167	79.0
WP_000839596.1\|4828477_4828693_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_000075094.1\|4828692_4829190_+	lysozyme RrrD	A5LH83	Enterobacteria_phage	1.7e-91	99.4
WP_001441931.1\|4829186_4829630_+\|lysis	lysis protein	M1FJ79	Enterobacteria_phage	4.3e-70	92.5
WP_000084844.1\|4829668_4830043_+	hypothetical protein	M1FPD9	Enterobacteria_phage	1.5e-47	80.6
WP_012896773.1\|4830274_4830553_+	hypothetical protein	K7PJR7	Enterobacteria_phage	1.3e-08	87.5
WP_000867568.1\|4830634_4831183_+\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	1.0e-57	84.2
WP_001573719.1\|4831154_4833083_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.1e-260	66.9
WP_000258997.1\|4833066_4833273_+\|head	phage head-stabilizing protein	K7PM10	Enterobacteria_phage	3.0e-10	55.4
WP_001441934.1\|4833269_4834862_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	4.2e-184	60.9
WP_001253893.1\|4834851_4836357_+	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	7.9e-100	53.5
WP_000256813.1\|4836393_4836741_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.6e-22	58.1
WP_000522650.1\|4836798_4837827_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	4.5e-115	61.6
WP_000201530.1\|4837878_4838253_+	hypothetical protein	NA	NA	NA	NA
WP_001204540.1\|4838245_4838599_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	3.4e-38	65.0
WP_001007370.1\|4838610_4839189_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.1e-78	91.7
WP_000683150.1\|4839185_4839581_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	2.9e-70	98.5
WP_001545921.1\|4839588_4840329_+\|tail	phage tail protein	A0A2I6TC77	Escherichia_phage	2.8e-130	98.0
WP_000479204.1\|4840344_4840767_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	3.7e-71	97.9
WP_000459449.1\|4840748_4841183_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	3.8e-63	98.3
WP_000840282.1\|4841175_4843737_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	88.8
WP_000847387.1\|4843733_4844063_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	9.9e-56	94.5
WP_001152542.1\|4844062_4844761_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	5.2e-131	97.8
WP_000194748.1\|4844766_4845510_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	3.3e-147	96.8
WP_000090860.1\|4845446_4846079_+\|tail	tail assembly protein	C6ZCZ4	Enterobacteria_phage	4.6e-94	97.6
WP_001545959.1\|4846139_4849538_+	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	90.3
WP_001545960.1\|4849596_4851525_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A0E3M194	Enterobacteria_phage	7.5e-111	60.1
WP_000422741.1\|4851606_4852032_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|4852028_4852379_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000080195.1\|4852409_4854023_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000654168.1\|4854190_4854469_+	hypothetical protein	A0A0E3JSQ1	Enterobacteria_phage	7.6e-25	57.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP015071

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

32901 : 66742

Enterobacteria_phage(15.38%)

integrase,transposase

attL 31750:31768|attR 53025:53043

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
31750:31768	attL	NA	NA	NA	NA
WP_165503372.1\|32901_35934_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	62.9
WP_000480968.1\|35837_36674_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001082319.1\|36673_37477_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_015586042.1\|37592_38294_+\|transposase	IS1-like element ISPa14 family transposase	A0A218MNG1	uncultured_virus	9.9e-37	55.0
WP_015586041.1\|38948_39728_-	APH(3')-VI family aminoglycoside O-phosphotransferase	E4ZFP6	Streptococcus_phage	1.1e-31	35.1
WP_001082319.1\|39955_40759_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_001067855.1\|41067_41772_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_004187345.1\|42122_42353_-	hypothetical protein	NA	NA	NA	NA
WP_004206912.1\|42450_42789_-	hypothetical protein	NA	NA	NA	NA
WP_004206911.1\|42978_43839_-	DUF4942 domain-containing protein	I6RTT5	Marinomonas_phage	2.8e-17	29.9
WP_004187364.1\|43911_44091_-	hypothetical protein	NA	NA	NA	NA
WP_004187367.1\|44767_45034_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004206910.1\|45078_45528_-	Mov34/MPN/PAD-1 family protein	NA	NA	NA	NA
WP_004206909.1\|45649_46012_-	DUF3085 domain-containing protein	NA	NA	NA	NA
WP_004206908.1\|46033_46297_-	hypothetical protein	NA	NA	NA	NA
WP_004206907.1\|46414_46825_-	hypothetical protein	NA	NA	NA	NA
WP_004206906.1\|46853_47333_-	hypothetical protein	NA	NA	NA	NA
WP_004206905.1\|47325_47571_-	hypothetical protein	NA	NA	NA	NA
WP_004187378.1\|47949_48513_-	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	5.2e-20	31.3
WP_004206904.1\|48522_48966_-	plasmid partitioning/stability family protein	NA	NA	NA	NA
WP_011091047.1\|48968_49943_-	plasmid segregation protein ParM	A0A0A7NPX4	Enterobacteria_phage	6.1e-85	52.0
WP_004187383.1\|50183_50924_-\|integrase	tyrosine-type recombinase/integrase	I3WFA4	Macacine_betaherpesvirus	9.5e-22	51.6
WP_020316874.1\|50942_51146_-	hypothetical protein	NA	NA	NA	NA
WP_004187390.1\|51187_51673_-	hypothetical protein	NA	NA	NA	NA
WP_004206901.1\|51669_52257_-	restriction endonuclease	NA	NA	NA	NA
WP_004187394.1\|52249_52498_-	helix-turn-helix transcriptional regulator	A0A248SLB9	Klebsiella_phage	1.6e-10	53.0
WP_015586036.1\|52494_52956_-	hypothetical protein	NA	NA	NA	NA
WP_004206899.1\|53096_53642_+	hypothetical protein	NA	NA	NA	NA
53025:53043	attR	NA	NA	NA	NA
WP_004206898.1\|53794_54202_-	hypothetical protein	NA	NA	NA	NA
WP_015062853.1\|54203_54782_-	hypothetical protein	NA	NA	NA	NA
WP_004206896.1\|54759_55116_-	hypothetical protein	NA	NA	NA	NA
WP_015059996.1\|55643_56831_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_015059995.1\|56849_57122_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015059994.1\|57118_57802_+	hypothetical protein	NA	NA	NA	NA
WP_004187411.1\|57846_58065_+	hypothetical protein	NA	NA	NA	NA
WP_004187413.1\|58067_58277_+	hypothetical protein	NA	NA	NA	NA
WP_019725070.1\|58399_59665_-	translesion error-prone DNA polymerase V subunit UmuC	A0A1W6JNT0	Morganella_phage	2.6e-112	50.4
WP_004187425.1\|59652_60087_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.2e-29	55.3
WP_020277900.1\|60179_60545_-	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_004187429.1\|60513_60771_-	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_025987686.1\|61102_62308_-\|transposase	IS4 family transposase	Q9E8P4	Bluetongue_virus	9.9e-170	72.0
WP_015059991.1\|63220_64018_+	carbapenem-hydrolyzing class D beta-lactamase OXA-48	NA	NA	NA	NA
WP_015586033.1\|64319_65231_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011790968.1\|65491_66742_+\|transposase	IS4-like element IS10A family transposase	Q9E8P4	Bluetongue_virus	4.2e-171	71.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP015070

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 64321

Escherichia_phage(40.0%)

transposase,protease,integrase

attL 8116:8132|attR 62418:62434

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001553854.1\|0_3117_-	HsdR family type I site-specific deoxyribonuclease	A0A220A398	Liberibacter_phage	3.7e-27	24.0
WP_001617890.1\|3238_4522_-	restriction endonuclease subunit S	F2Y1N5	Organic_Lake_phycodnavirus	2.2e-10	26.5
WP_001617892.1\|4518_6075_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.2e-104	42.7
WP_001190712.1\|6257_6479_+	type II toxin-antitoxin system Phd/YefM family antitoxin	A0A222YXU1	Escherichia_phage	6.7e-32	100.0
WP_001216034.1\|6478_6859_+	type II toxin-antitoxin system death-on-curing family toxin	A0A077SK56	Escherichia_phage	1.1e-63	100.0
WP_001513661.1\|6863_7043_+	hypothetical protein	Q71TH5	Escherichia_phage	3.5e-23	96.6
WP_001513660.1\|7070_7430_+	hypothetical protein	A0A077SLM1	Escherichia_phage	5.0e-45	98.9
WP_001513659.1\|7716_8034_-	hypothetical protein	NA	NA	NA	NA
8116:8132	attL	NA	NA	NA	NA
WP_012372828.1\|8261_9278_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.4
WP_001373486.1\|9485_10889_+	S-methylmethionine permease	NA	NA	NA	NA
WP_000081352.1\|10875_11808_+	homocysteine S-methyltransferase	NA	NA	NA	NA
WP_000361610.1\|15150_16128_+	replication initiation protein	J9Q7H0	Salmonella_phage	1.4e-100	59.2
WP_001066941.1\|16412_17153_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	1.6e-24	57.6
WP_001309252.1\|17273_17462_-	hypothetical protein	NA	NA	NA	NA
WP_001072358.1\|17828_18998_+	hypothetical protein	NA	NA	NA	NA
WP_001322642.1\|19844_20117_-	transcriptional regulator	NA	NA	NA	NA
WP_001298664.1\|21359_23330_+	TonB-dependent hemoglobin/transferrin/lactoferrin family receptor	NA	NA	NA	NA
WP_000977394.1\|23336_24128_+	DUF4198 domain-containing protein	NA	NA	NA	NA
WP_001323403.1\|24866_25646_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	1.5e-139	100.0
WP_001310017.1\|25645_26668_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	3.2e-201	99.7
WP_000612626.1\|27747_28095_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000839179.1\|28091_28496_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_001189113.1\|28997_30506_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	6.2e-44	31.8
WP_001020413.1\|32771_33947_-	enterotoxin production-related protein TieB	NA	NA	NA	NA
WP_001100763.1\|34015_36277_-	TonB-dependent receptor	NA	NA	NA	NA
WP_001398199.1\|37349_37751_-	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_000557619.1\|37683_37941_-	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_000616807.1\|38033_38687_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001617855.1\|39626_40484_-	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_031943482.1\|40476_40551_-	RepA leader peptide Tap	NA	NA	NA	NA
WP_000083850.1\|40787_41042_-	replication regulatory protein RepA	NA	NA	NA	NA
WP_023144756.1\|41338_41473_-	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_000080195.1\|41908_43522_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000624722.1\|43552_43903_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000422741.1\|43899_44325_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_013023861.1\|44883_45096_-	hypothetical protein	NA	NA	NA	NA
WP_000139341.1\|45226_45787_-	fertility inhibition protein FinO	NA	NA	NA	NA
WP_000205718.1\|45841_46588_-	conjugal transfer pilus acetylase TraX	A0A077JBM8	Xanthomonas_phage	3.2e-09	30.9
WP_001617867.1\|46607_51878_-	conjugative transfer relaxase/helicase TraI	NA	NA	NA	NA
WP_023356304.1\|51877_54094_-	type IV conjugative transfer system coupling protein TraD	NA	NA	NA	NA
WP_000199914.1\|54090_54870_-	hypothetical protein	NA	NA	NA	NA
WP_000850429.1\|55072_55804_-	complement resistance protein TraT	NA	NA	NA	NA
WP_000605862.1\|55835_56333_-	entry exclusion protein	NA	NA	NA	NA
WP_001007062.1\|56351_59171_-	conjugal transfer mating pair stabilization protein TraG	NA	NA	NA	NA
WP_000944328.1\|59167_60541_-	conjugal transfer protein TraH	NA	NA	NA	NA
WP_001348758.1\|60527_60953_-	F-type conjugal transfer protein TrbF	NA	NA	NA	NA
WP_071571857.1\|60900_61248_-	P-type conjugative transfer protein TrbJ	NA	NA	NA	NA
WP_000059829.1\|61177_61723_-	type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB	NA	NA	NA	NA
WP_001617873.1\|61709_61994_-	type-F conjugative transfer system pilin chaperone TraQ	NA	NA	NA	NA
WP_001348757.1\|62120_62441_-	conjugal transfer protein TrbA	NA	NA	NA	NA
62418:62434	attR	NA	NA	NA	NA
WP_000019450.1\|63340_64321_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	1.8e-185	99.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP015069

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP015071

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP015070

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection