CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP015136	Luteitalea pratensis strain DSM 100886 isolate HEG_-6_39 chromosome, complete genome	9 crisprs	csa3,DEDDh,PrimPol,cas3,DinG	0	2	6	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015136_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_1

140940-141046

Orphan

Consensus_repeat	Method
GACGGTCGCTTCGCTCCCGGCTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_1

>merge|NZ_CP015136|1|140940-141046|CRISPRCasFinder
GACGGTCGCTTCGCTCCCGGCTTCCGCCTCCGCCTGACGGTCCCTTCGCTCCCGGCTTCGGCGAGACAGGTCCGCCTCCGCCTGACGGTCCCTTCGCTCCCGGCTTC

>NZ_CP015136|1|1|140940-141046|CRISPRCasFinder
GACGGTCGCTTCGCTCCCGGCTTC	CGCCTCCGCCTGACGGTCCCTTCGCTCCCGGCTTCGGCGAGACAGGTCCGCCTCCGCCT
GACGGTCCCTTCGCTCCCGGCTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_162271265.1\|126634_128473_+\|NADH-quinone-oxidoreductase-subunit-NuoF	unknown	unknown	gnl\|CDD\|224806
NZ_CP015136.1\|WP_110168972.1\|141074_141311_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110174449.1\|141785_142229_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP015136.1\|WP_110168978.1\|148375_148627_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110174450.1\|142576_142975_+\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|223619
NZ_CP015136.1\|WP_110168966.1\|131865_132330_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110168967.1\|132335_132977_+\|toll/interleukin-1-receptor-domain-containing-protein	unknown	unknown	gnl\|CDD\|379328
NZ_CP015136.1\|WP_110168965.1\|131131_131728_+\|NADH-quinone-oxidoreductase-subunit-I	unknown	unknown	gnl\|CDD\|235637
NZ_CP015136.1\|WP_157898580.1\|132976_135943_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|315987
NZ_CP015136.1\|WP_110168976.1\|146180_146714_+\|NfeD-family-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110168960.1\|125315_126638_+\|NADH-quinone-oxidoreductase-subunit-D	unknown	unknown	gnl\|CDD\|223722
NZ_CP015136.1\|WP_110174451.1\|148623_149043_-\|Rieske-2Fe-2S-domain-containing-protein	unknown	unknown	gnl\|CDD\|239558
NZ_CP015136.1\|WP_110168977.1\|146729_148319_+\|flotillin-family-protein	unknown	unknown	gnl\|CDD\|225177
NZ_CP015136.1\|WP_110168973.1\|141364_141775_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924
NZ_CP015136.1\|WP_110168974.1\|143000_145619_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|274576
NZ_CP015136.1\|WP_110168964.1\|130040_131132_+\|NADH-quinone-oxidoreductase-subunit-H	unknown	unknown	gnl\|CDD\|235692
NZ_CP015136.1\|WP_110168975.1\|145620_145983_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|163261
NZ_CP015136.1\|WP_110168963.1\|128460_130044_+\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|273904
NZ_CP015136.1\|WP_110168969.1\|136447_137035_-\|dihydrofolate-reductase-family-protein	unknown	unknown	gnl\|CDD\|334719
NZ_CP015136.1\|WP_157898581.1\|137171_138524_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225233

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_162271265.1\|126634_128473_+\|NADH-quinone-oxidoreductase-subunit-NuoF	gnl\|CDD\|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	0
NZ_CP015136.1\|WP_110174449.1\|141785_142229_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.20653e-26
NZ_CP015136.1\|WP_110168977.1\|146729_148319_+\|flotillin-family-protein	gnl\|CDD\|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	1.09451e-55
NZ_CP015136.1\|WP_110174451.1\|148623_149043_-\|Rieske-2Fe-2S-domain-containing-protein	gnl\|CDD\|239558	cd03476, Rieske_ArOX_small, Small subunit of Arsenite oxidase (ArOX) family, Rieske domain; ArOX is a molybdenum/iron protein involved in the detoxification of arsenic, oxidizing it to arsenate. It consists of two subunits, a large subunit similar to members of the DMSO reductase family of molybdenum enzymes and a small subunit with a Rieske-type [2Fe-2S] cluster. The large subunit of ArOX contains the molybdenum site at which the oxidation of arsenite occurs. The small subunit contains a domain homologous to the Rieske domains of the cytochrome bc(1) and cytochrome b6f complexes as well as naphthalene 1,2-dioxygenase. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer.	3.54193e-22
NZ_CP015136.1\|WP_110174450.1\|142576_142975_+\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	1.39547e-39
NZ_CP015136.1\|WP_110168967.1\|132335_132977_+\|toll/interleukin-1-receptor-domain-containing-protein	gnl\|CDD\|379328	pfam13676, TIR_2, TIR domain. This is a family of bacterial Toll-like receptors.	7.55154e-14
NZ_CP015136.1\|WP_110168965.1\|131131_131728_+\|NADH-quinone-oxidoreductase-subunit-I	gnl\|CDD\|235637	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI.	9.68493e-44
NZ_CP015136.1\|WP_157898580.1\|132976_135943_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	7.46782e-12
NZ_CP015136.1\|WP_110168960.1\|125315_126638_+\|NADH-quinone-oxidoreductase-subunit-D	gnl\|CDD\|223722	COG0649, NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion].	1.21386e-169
NZ_CP015136.1\|WP_157898581.1\|137171_138524_-\|hypothetical-protein	gnl\|CDD\|225233	COG2358, Imp, TRAP-type uncharacterized transport system, periplasmic component [General function prediction only].	1.15475e-19
NZ_CP015136.1\|WP_110168974.1\|143000_145619_-\|ABC-transporter-permease	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	0
NZ_CP015136.1\|WP_110168964.1\|130040_131132_+\|NADH-quinone-oxidoreductase-subunit-H	gnl\|CDD\|235692	PRK06076, PRK06076, NADH-quinone oxidoreductase subunit NuoH.	1.62928e-110
NZ_CP015136.1\|WP_110168975.1\|145620_145983_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	2.98661e-49
NZ_CP015136.1\|WP_110168963.1\|128460_130044_+\|(2Fe-2S)-binding-protein	gnl\|CDD\|273904	TIGR01973, NADH-quinone_oxidoreductase_subunit_G, NADH-quinone oxidoreductase, chain G. This model represents the G subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria while translocating protons, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes related subunits from formate dehydrogenase complexes. [Energy metabolism, Electron transport].	9.9764e-126
NZ_CP015136.1\|WP_110168969.1\|136447_137035_-\|dihydrofolate-reductase-family-protein	gnl\|CDD\|334719	pfam01872, RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis. This domain is found in the C-terminus of RibD/RibG, in combination with pfam00383, as well as in isolation in some archaebacterial proteins. This family appears to be related to pfam00186.	2.75814e-20
NZ_CP015136.1\|WP_110168973.1\|141364_141775_-\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.0468e-44

>NZ_CP015136.1|WP_157898581.1|137171_138524_-|hypothetical-protein
MTVSVVALVFAFVALLEFLTPSLAYQLRDRVVETASGRRGRTYRIALGSAIGSSYRAGTVLNQHLRDRAGYELELVSTVAPGNVRLLLDASQRIDLAVVSSVDDDAVRSSGVYGVAALEPQHFFVIVRTDSALRDVRDLTGAVNPGVRDAGHPPTLGERVLDYYGLLTSTPGTGAPVTVVRPRGSNVADFESGHMVAATRTQFLRSPLIDEILNTADYRLVPIRDHEALARSIPGARPGFIPAGLYGPGRRIPSEAVPTLVVTQLLVARPDVPGRVVRDILECMYHPRFARDAQYAFTESTGRDVGGLPLHPAATIFYGRNDLVTSDRLGRLSFVGSVLVALFTLAQYAIRLRRNDSLRDRRRLLGDELARLEQLRGQIAGDSDAGTRRALVCDADEVLSRAEQQAAAGQWSSEDIQALRSLHALCRVSEGRLPASAEPPPVPVAAPSPR
>NZ_CP015136.1|WP_110168969.1|136447_137035_-|dihydrofolate-reductase-family-protein
MRKLIVSEFVSLDGVMQAPGGKDEDRDGGFEHGGWTIPYWHDDIGAAFGGLMQGVDAFLLGRRTYVTHADAFEPLPPGDPFGDLMNAPRKYVVSKTLTQPIWRNTTVIRDNVVGSIRALKAEPGGTILTDGSSQLVHAMIEHDLVDELHLLVYPLALGSGKRALPAGVHATFELASATPYPTGVVGLHYRRRRAS
>NZ_CP015136.1|WP_157898580.1|132976_135943_+|tetratricopeptide-repeat-protein
MASPVSEDVTRLHEVVTFYSYKGGTGRTMALANAACLITRRDPGCRVLAVDWDLEAPGLHYYLHPAQTGEAESAVDGLVEYFSQVQAAIKDRRGEAVDDEAVLANIPLSAHCRETVVPNVHLMQAGRFDSTYQARLSRLDWQEIYRDSPTLFRTFASLLLRQYDVVLVDSRTGLTDISGICTSLLPDKVVVVFTANQQSLTGVEQLVRSSVEYRRGSPDLRPLLVYPLPSRIDDQREQLRRQWRHGDATLGIEGFQPQFERILRGAYALDGCDLSDYFNEVQVQHSPDYSYGEKVAALAAPDHDRFSIIRSYEALLDWLGSSAAPWETPAQARERTRLESLLQREAEFQRDATIDVAPLLALQAEIVRLSQQHRGATHLDTVRAMQRYVRTALGGGGDLSAALTVLESLGAALPQLRVPVRVHAIGAMLQATPSLRAQGQSAAAERLGRLALSEIEALRGPSGASADVVAALDALGSQLQDAAAFAEARTLREFVLEERRRCDGDERQSTLNASRRLAETHWALGNYATARSMLEHAGTIAATVLGEQARETLAIRQQLAEVLAEQGHADQALQLTDAVLEARSRLLGPAHEDTLATLALRSDVLRDSGRLDEARAACEAVVAAQSASLGNDNPDTLASRDRLAAILQAQGHLAEARAAQEAVVEAYGRVFGAQHPVTLRATANLAATLWALGALSEARALEQHVLDVRRDVLGPAHPETLTAMNNLASTLWSQGDLVGARALEEQALETRRRVLGDDHPATLVSMGNLAETLRLQGELPEAKALGMAVIEGRRRTLGPEHPETLAAMNNLALTLRALGDAEQARRLLEQVVEVRRRVQGHEHPDTLKAAYNLAETLRQAGDLTKARQIHETVLAARRRILGHEDRDTLASMVELSLTASAQDDFATARPLLEHVLEEYLRLAGEDDRRTLAVRTHLARALIALGDVAGAQLHQEHLASAWARRVEKDRIESGPRGIGDYPGARGTRS
>NZ_CP015136.1|WP_110168967.1|132335_132977_+|toll/interleukin-1-receptor-domain-containing-protein
MTDTLHACFISYRHPATAGSREEKLIAHVFKAISDHVEMYTHTHQVYFDQKRLVPGYQYDEKLAEAICRSACMVIVYWPAYLESDYCLQEIEAMLEIEKRRRKKLGSELHGCRLIIPFIVRGRFEDLPNAVRDGCQYLDYSRQATNPHFNIGEDEETSAKLFEIANYIKSLCDKLQRVGADVVGTCKDYGFPARMQVTQPEMAPPPPPPFPGQ
>NZ_CP015136.1|WP_110168966.1|131865_132330_+|hypothetical-protein
MRTFGLLIGLLVATPLAPTDQSPLVPRDTISDQDVPDHGDNINARYIVEHADIRGVPEDDLTEALQDDLRGLIGQRLDSGAADRLQERMVREFPDYDVSRRIERGNESAASGSSTRLTGKRGINSMYHPGHPHAHADVLSSSGCDHDGLSASAA
>NZ_CP015136.1|WP_110168965.1|131131_131728_+|NADH-quinone-oxidoreductase-subunit-I
MGVKVLRRRELTFWEELYIPQIFSGLRITSAHFFRNLFLHAAHSVGALTHRAASATFQYPEQPRPLARRFRSRHRLTVREEGTPRCVGCMLCETVCPARCITIVAGEHPDPNVEKYPVRFDIDLGICVYCGYCVEVCPEDAIRMDTGILDVAAYSRDEMKLDIHELMNPALRKPVVECDLKFPHECRHSGGEIKGSWE
>NZ_CP015136.1|WP_110168964.1|130040_131132_+|NADH-quinone-oxidoreductase-subunit-H
MMPDLLIKLTLVGIVFFGVLNLAGLHTWIERKQSAIMQDRIGANRASIYGFKLMGLFHPLADAVKMFTKEDIIPDGADRVLHMLAPALSVFFALVAFAGIPFGDRVVIGERVIDLQVARIDVALLYVFAMLSLGVYGVILAGFASRNNYAMLGGLRATAQMISYEIALGIAIIGVIMVYGTLDLQELVRGQGRYVAGWIPLWGIVVQPVAFFVFLTAALAATKRTPFDMPEGESEVIGYFVEYSGMKFGMFYLADFLETIMVACLVTTLFLGGWQVPYLMPDGFHFPWGAELPLSSWTYAVLGVGSFSIKVLAFCWLFMQIRWTLPRLRYDQLMVLGWKGLFPIAVANVLVTAAALALLGGKS
>NZ_CP015136.1|WP_110168963.1|128460_130044_+|(2Fe-2S)-binding-protein
MPTLTIDGRQVSSPDGTTVIQAAETLGIFVPRYCYHPALSVAGNCRICLVEVEKTAKLQIACNTPVSEGMVVHTTSEKAEDGRRAVLEFLLANHPLDCPVCDQSGECELQNFYMNFGLYDARFREQKVKKKKAVAIGPHVMLDQERCILCSRCVRFTDEITRTGEFGIFNRGDRAELGLYPGQELNNPYSGNVIDVCPVGALTEQDFRFKARVWYLSSAPSVCNGCAQGCNVDVHYVLDRPHLNGGARVMRLKPRYNPDVNQWWMCDEGRFGFHWIDRGRLTHVRHRGAESTWEQAVADISAALAPRDSGAARLGVIASSGLSNEELFLIREVFQRGLGASVMAAVPVPPGYSDDFLIRADKSPNTRGATILGLAGPGAPPVDSILADARAGRIDALWVFGLDLAALIGDAELDALSGTVDLLIYSGTNDNRTAAAAHWVLPTAAYLEKDGTFVNCQGRVQRIGCALPPLAGSREDWAVLLDIAQQLDHPFPWRTTQEIFLAMAKTVAAFEGMSYEAMGSQGLSIRQ
>NZ_CP015136.1|WP_162271265.1|126634_128473_+|NADH-quinone-oxidoreductase-subunit-NuoF
MNFDALDSQAREIIQRYDQPRAAMLPLLWLVQAELGHVPAEAEFWVGRHLGVAVSHVREVVSFYSMFRTTPGGRRELRVCTSLPCLLRGAGDVLTRIQDQLGVRAGETTPGGELTVTAVECLCACEIAPMAQLDEQFVGPLDEPGALESILRDALRPATFAPLGGAKAGEPGDACHEPEPFISTAGPVLSTRFGNADGTWFDAYVESGGYVAAKRALSMTPAQIIDEISQSNLRGLGGAGFPTAKKWSFIPKNSARPVYLVVNADEGEPGTFKDRYILERDPHALLEGMIVATYSIGSHKAYVYIRGEYFRSADRFNRAVQEAHAHGWLGTNIQGSGFDLDVVVHRGAGAYICGEETALLTSLEGGKGFPKLKPPFPAISGLFHCPTIVNNVETLACVPFILREGAERFARLGTSTQGGTRLFSVCGHVQRPGLYEAPVGVSLRELIEGHAGGVRDGRTLKAVVPGGISAKVLTASEIDVQMDFDSLMAAGSMAGSGGVIVMDDTTCMFEALQSASKFFAHESCGQCSPCREGTGWVYRILNRIAEGKGRPQDLDDLLAIARDMEGKTICVFADAAAWPVQSYITKFREEFDAHVRIGTCPARSREVAACQP
>NZ_CP015136.1|WP_110168960.1|125315_126638_+|NADH-quinone-oxidoreductase-subunit-D
MNTREMLLNVGPAHPAMHGIIRIVTTLDGERIVDIDVEIGYLHRGFEKMAETVDYNGVMPYTDRLNYVSPLINNMGYCMAVEKLLGMSVPDRCHYIRVIMSEISRISDHLTCVGASAMELGAFTVFLYMIKAREYLWDLVEMVTGARLTVTYCRVGGVKGDLPAGFDEACANAFKETRLVIKESDTLLTRNRIFVDRMSGTGKISAEDAISHGITGPFLRGCGVAYDVRKDCPYAVYDRLEFDVPVGTRGDNLDRYMVRMEEMEQSMRIVEQALREIPDGPVLASPDTAKPMPAAEMVDRAKVGNIRSIADSVAVTDPTLDGASKPLHLHIAGDEKRVFLPPKEDTYGNIEGLMQHFKLVMYGHGIQPPAGEVYFPVEGANGELGFYIVSDGSSSAYRVRVRPPCFAIMSALPKLLIGDMIADLTPTFGSVNMIGGELDR
>NZ_CP015136.1|WP_110168972.1|141074_141311_-|hypothetical-protein
MNWNSWIRQFHRWVSVAFTLTVIANFVVMGMNGGQQPPPYVTYSPLLPLALLMFTGLYLFALPYVARARSGRGSLSSS
>NZ_CP015136.1|WP_110168973.1|141364_141775_-|VOC-family-protein
MDITIHSSFLPHDDPDASLAFYRDTLGFEVRNDVGYNGMRWITVGPVGQPGISIVLHPPAATPGLTGDERRTIAEMMAKGTYAMVILATRDLDGTFERLQASGADVIQEPTMQPYGIRDCAFRDPAGNHIRINEVR
>NZ_CP015136.1|WP_110174449.1|141785_142229_-|helix-turn-helix-transcriptional-regulator
MNSRPAVAPHLRELALLRRVRDRMDREYDQPLDVEALARGVQMSAGHLSRQFKLAYGESPYAYLMTRRIERAMALLRRGDLSVTDVCFEVGCSSLGTFSTRFTELVGVPPSVYRRDAAHATTGMPSCVAKQVTRPVRNREARAQDRT
>NZ_CP015136.1|WP_110174450.1|142576_142975_+|FKBP-type-peptidyl-prolyl-cis-trans-isomerase
MLGENRGATSMIPAPADVAAPPADATVTPSGLASRQLEAGTGTQHPGPRSRVLVHYSGWTTDGQMFDSSVSRGEPIAFGLYQVIAGWTEGVQLMVEGEKRRFWIPEPLAYGGRAGAPAGMLVFDVELIRIES
>NZ_CP015136.1|WP_110168974.1|143000_145619_-|ABC-transporter-permease
MFWRRRRSEDDISDEIRTHLDLEADDLVAEGLPEQQARAAARREFGSVALTRERLYEKGRVPWLDDVVRDLRHSVALYRRAPGFTIAVVVTLALGIGLNTAIFSFVNALLLRPLPVPNSERLVAIHTSDFSGPAHGSTGYPDYLDFRDNARDVLSGLAAYSMELMNLSDGAASDRVQGHVVTQNYFSVVGVDVARGRVFGPADEDVVVVSHGLWQRMLGGREDVLGRRLTINGKPSVVIGVAPPGFTGLLRGLPADLWLPLERQSQLADQLTERGSRWLTVVGRLADGVELPRAQAAFKVIGDQLHRAYPREWTDLKGEGRRITLEPANQSLLVDRADVLPFMTTLMAVVGIVLLLACVNVSNLMLARAAVRSREMAIRLSVGAGRARVLRQLFTESVLLAMLAGLASTLVAFAATTQLVRMQPPLPLRISLDLSPDARVLAFTALMSLLTAMLFGLLPALRMTRPNLTTALKGGIADAGVHRLRRGSLRNGLVAVQVALSVVLVVGAGLSVLSLRRAGAVDVGFEPRNVVIASLSAGRQGYDEARARSFFEQLVARIEALPGVRSAALASIVPLDFSGQRTRVDLQGYTPRNGEDMEINFNVVGSRYFETMRVPLVQGREFDATDRVGAMGAVIVNDALVRRYWPDGIAIGKQIRRGQSAFTVVGVTTDGKYRSLSEPPLPYFYLSLGQNLQSDLSLHVRTDREPVAVAGAIRATVRELDPDLPLTDVRTMEDHLGLVLMPLHAAATLLGAFGALALGLAVVGIYSVMACTVSQHTREIGIRMALGARLGDVLALVLREGLVVVGVGLLAGGAAAAGVTRFAASLFYGVSPTDPMTFAGALGLLGVAGLLAALVPALRAARIHPSDALRQG
>NZ_CP015136.1|WP_110168975.1|145620_145983_-|PadR-family-transcriptional-regulator
MPTKRQDSDRVALLQGTLDLLILKTLVLGPHHGQGMARTIQRQSEDAFSVDHGSLYLALQRLEDKGWITGRWGASENNRRARFYTLTRQGRAQLGEKATEWRKLARAIALILGPELGEAD
>NZ_CP015136.1|WP_110168976.1|146180_146714_+|NfeD-family-protein
MDLLPPLSAFTVFLSICAVGFLFLVLALAFGGLFDFLETDHDFATGGPGFFSSRVMAVFVTAFGGFGAVATYYGLGPIPASLVGFGSGIVFGGAIYALARALYNQQVSTEVRADDLVGAVGRVVIGIPPGGVGQVRLRLGEELMDKIARTRDGVAIAENTSVQIEEVLGETVIVKKT
>NZ_CP015136.1|WP_110168977.1|146729_148319_+|flotillin-family-protein
MTENVQLASLILSILGVVLSLFAAAFLFSRNYIKVSPNAVAVLSGRKRKLPDGRTVGYRMVRGGAALRIPLLEKVEYLHLNVMTIPLEIRRAYTLKGVPVSVKAVANVKIRGDDSSLQAAAERFLGMSHDQVQKVIFQTLEGHLRSILGTLTVEEVNSDRQSFAQKLTTEAATDLEKMGIGVDVLTIQEISDEEGYLDALGKRRTAEVKRDATIGEAEAHRDAKIKSSQALQEGEKAKFQADAEIAQSSRDFMIRQAQYQAEIETQKARAAQAGPLAEATARQGVVAEEVRVEKTRTQEAIAVQEQEVLRRQKELDATVIKPAEADRQAAVVRAEAAKQSAILEAEGRRSAMIAMAEAEQEKLRKEGAGRAAAVEAEGRAEAAKIEAIGLAQAKAIEAQGVAEATAILRKAEAWKEFNDAARLQTILEKLPAIIEASSGVFGAVAAPFGNIDKLVVMDTGNGSSENGGGSLARLAQTSPAVVFNLLQQLEALGLSVPDVMQQLGVKGTLPVVPTPPAASPTAVTPPKRG
>NZ_CP015136.1|WP_110168978.1|148375_148627_-|hypothetical-protein
MSGSLKRPFSREQRTTIVYGMLVFVLIVVILQLWLLTATMNAWLGGDEAVVWPAAAVSAAGFALNAGLLTYLGRIERTRKLGE
>NZ_CP015136.1|WP_110174451.1|148623_149043_-|Rieske-2Fe-2S-domain-containing-protein
MKFLVLTSGAFTLGQVLIGLQNWYRKRAGQPAMRRIASVDDLAVGAALLFTYPDENEPCLLVRLTTSEFVAFSQKCTHLSCAVIPRPAEGSFYCPCHEGRFDLRTGAPTAGPPRRPLTRIVLDIRGRDLYAVGVEERAI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015136_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_2

2271525-2271610

Orphan

Consensus_repeat	Method
CGTTCGGCGTTCGTCGATTTGGCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_2

>merge|NZ_CP015136|2|2271525-2271610|CRISPRCasFinder
CGTTCGGCGTTCGTCGATTTGGCTTGCCCGGGTGCCCCGTGCCCGGTACCCGGTGGCGCCGCGTTCGACGTTCAACGTTCGGCGTT

>NZ_CP015136|2|2|2271525-2271610|CRISPRCasFinder
CGTTCGGCGTTCGTCGATTTGGCTT	GCCCGGGTGCCCCGTGCCCGGTACCCGGTGGCGCCG
CGTTCGACGTTCAACGTTCGGCGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_110170495.1\|2270787_2271390_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110170488.1\|2262845_2263784_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_157898939.1\|2269231_2270134_+\|SgcJ/EcaC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|380345
NZ_CP015136.1\|WP_110170503.1\|2281497_2282007_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379324
NZ_CP015136.1\|WP_110170498.1\|2275603_2276935_+\|TldD/PmbA-family-protein	unknown	unknown	gnl\|CDD\|223389
NZ_CP015136.1\|WP_110170496.1\|2272972_2273983_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|225070
NZ_CP015136.1\|WP_110170502.1\|2280261_2281242_+\|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl\|CDD\|271332
NZ_CP015136.1\|WP_110170489.1\|2263793_2264987_-\|esterase	unknown	unknown	gnl\|CDD\|225256
NZ_CP015136.1\|WP_110170501.1\|2278543_2280100_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|226233
NZ_CP015136.1\|WP_110170487.1\|2261774_2262713_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
NZ_CP015136.1\|WP_110170500.1\|2277635_2278535_-\|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl\|CDD\|235467
NZ_CP015136.1\|WP_110170494.1\|2270245_2270788_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP015136.1\|WP_110170504.1\|2282003_2282798_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP015136.1\|WP_110170492.1\|2267612_2268230_-\|gluconate-2-dehydrogenase-subunit-3-family-protein	unknown	unknown	gnl\|CDD\|379295
NZ_CP015136.1\|WP_110170497.1\|2274015_2275587_+\|TldD/PmbA-family-protein	unknown	unknown	gnl\|CDD\|223389
NZ_CP015136.1\|WP_110170491.1\|2265718_2267398_-\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_CP015136.1\|WP_157898938.1\|2268460_2268961_-\|DinB-family-protein	unknown	unknown	gnl\|CDD\|225200
NZ_CP015136.1\|WP_110170499.1\|2277089_2277461_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|225861
NZ_CP015136.1\|WP_110174606.1\|2271692_2272727_-\|glycoside-hydrolase-family-43-protein	unknown	unknown	gnl\|CDD\|350131
NZ_CP015136.1\|WP_110170490.1\|2265107_2265629_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377971

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_110170502.1\|2280261_2281242_+\|SMP-30/gluconolactonase/LRE-family-protein	gnl\|CDD\|271332	cd14962, NHL_like_6, Uncharacterized NHL-repeat domain in bacterial proteins. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	5.73232e-06
NZ_CP015136.1\|WP_110170500.1\|2277635_2278535_-\|N-acetylmuramic-acid-6-phosphate-etherase	gnl\|CDD\|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	4.8384e-146
NZ_CP015136.1\|WP_157898939.1\|2269231_2270134_+\|SgcJ/EcaC-family-oxidoreductase	gnl\|CDD\|380345	cd02215, cupin_QDO_N_C, quercetinase, N- and C-terminal cupin domains. This family contains quercetinase (also known as quercetin 2,3-dioxygenase, 2,3QD, QDO and YxaG; EC 1.13.11.24), a mononuclear copper-dependent dioxygenase that catalyzes the cleavage of the flavonol quercetin (5,7,3',4'-tetrahydroxyflavonol) heterocyclic ring to produce 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. Bacillus subtilis quercetin 2,3-dioxygenase (QDO) is a homodimer that shows oxygenase activity with several divalent metals such as Mn2+, Co2+, Fe2+, and Cu2+, although the preferred one appears to be Mn2+. The dioxygen binds to the metal ion of the Cu-QDO-quercetin complex, yielding a Cu2+-superoxo quercetin radical intermediate, which then forms a Cu2+-alkylperoxo complex which then evolves into endoperoxide intermediate that decomposes to the product. Quercetinase is a bicupin with two tandem cupin beta-barrel domains, both of which are included in this alignment model. The pirins, which also belong to the cupin domain family, have been shown to catalyze a reaction involving quercetin and may have a function similar to that of quercetinase.	8.58572e-28
NZ_CP015136.1\|WP_110170503.1\|2281497_2282007_+\|ATP-binding-protein	gnl\|CDD\|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	2.22014e-30
NZ_CP015136.1\|WP_110170498.1\|2275603_2276935_+\|TldD/PmbA-family-protein	gnl\|CDD\|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	7.16553e-50
NZ_CP015136.1\|WP_110170496.1\|2272972_2273983_-\|amidohydrolase-family-protein	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	1.65903e-28
NZ_CP015136.1\|WP_110170489.1\|2263793_2264987_-\|esterase	gnl\|CDD\|225256	COG2382, Fes, Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism].	2.87335e-23
NZ_CP015136.1\|WP_110170492.1\|2267612_2268230_-\|gluconate-2-dehydrogenase-subunit-3-family-protein	gnl\|CDD\|379295	pfam13618, Gluconate_2-dh3, Gluconate 2-dehydrogenase subunit 3. This family corresponds to subunit 3 of the Gluconate 2-dehydrogenase enzyme that catalyzes the conversion of gluconate to 2-dehydro-D-gluconate EC:1.1.99.3.	7.68738e-10
NZ_CP015136.1\|WP_110170501.1\|2278543_2280100_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|226233	COG3710, CadC, DNA-binding winged-HTH domains [Transcription].	3.7729e-30
NZ_CP015136.1\|WP_110170494.1\|2270245_2270788_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	1.11366e-16
NZ_CP015136.1\|WP_110170504.1\|2282003_2282798_+\|hypothetical-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	0.00129233
NZ_CP015136.1\|WP_110170487.1\|2261774_2262713_-\|HD-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	2.10379e-54
NZ_CP015136.1\|WP_110170497.1\|2274015_2275587_+\|TldD/PmbA-family-protein	gnl\|CDD\|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	6.61516e-74
NZ_CP015136.1\|WP_110170491.1\|2265718_2267398_-\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	3.59154e-63
NZ_CP015136.1\|WP_157898938.1\|2268460_2268961_-\|DinB-family-protein	gnl\|CDD\|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	2.57564e-28
NZ_CP015136.1\|WP_110170499.1\|2277089_2277461_+\|VOC-family-protein	gnl\|CDD\|225861	COG3324, COG3324, Predicted enzyme related to lactoylglutathione lyase [General function prediction only].	5.78495e-30
NZ_CP015136.1\|WP_110174606.1\|2271692_2272727_-\|glycoside-hydrolase-family-43-protein	gnl\|CDD\|350131	cd18619, GH43_CoXyl43_like, Glycosyl hydrolase family 43 protein such as metagenomic beta-xylosidase/alpha-L-arabinofuranosidase CoXyl43. This glycosyl hydrolase family 43 (GH43) subgroup belongs to the GH43_AXH-like subgroup which includes enzymes that have been characterized with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55), alpha-1,2-L-arabinofuranosidase 43A (arabinan-specific; EC 3.2.1.-), endo-alpha-L-arabinanase as well as arabinoxylan arabinofuranohydrolase (AXH) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. Included in this subfamily is the metagenomic beta-xylosidase/alpha-L-arabinofuranosidase CoXyl43, which shows synergy with Trichoderma reesei cellulases and promotes plant biomass saccharification by degrading xylo-oligosaccharides, such as xylobiose and xylotriose, into the monosaccharide xylose. Studies show that the hydrolytic activity of CoXyl43 is stimulated in the presence of calcium. Several of these enzymes also contain carbohydrate binding modules (CBMs) that bind cellulose or xylan. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	0
NZ_CP015136.1\|WP_110170490.1\|2265107_2265629_+\|hypothetical-protein	gnl\|CDD\|377971	pfam08310, LGFP, LGFP repeat. This 54 amino acid repeat is found in many hypothetical proteins. Several hypothetical proteins from C.glutamicum and C.efficiens along with PS1 protein contain this repeat region. The N-terminus region of PS1 contains an esterase domain which transfers corynomycolic acid. The C-terminus region consists of 4 tandem LGFP repeats. It is hypothesized that the PS1 proteins in Corynebacterium, when associated with the cell wall, may be anchored via the LGFP tandem repeats that may be important for maintaining cell wall integrity [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16]. Deletion of Corynebacterium glutamicum csp1 protein results in a 10-fold increase in the cell volume of the organism and infers the corresponding proteins involvement in the cell shape formation. The secondary structure of each repeat is predicted to comprise two beta-strands and one alpha-helix [Adindla et al. 2004].	3.59118e-24

>NZ_CP015136.1|WP_110170495.1|2270787_2271390_+|hypothetical-protein
MATTRSEPPQCSAPISEEILLEYWMAALDEAAETAIEEHLFACDECGGRLRGTIALAEALRDVARSGSLRVIVSDDFVRQAKAEGRTVREYTPPRGGVVACTISADDDFLIARLVAELAGLPRVDLGIYDSEGRERGRMADVPVDAAARAVLYQESATFAKAAPDDVMVLRLLAVEAGGERVLGEYEMRHTRTIPGPAAW
>NZ_CP015136.1|WP_110170494.1|2270245_2270788_+|sigma-70-family-RNA-polymerase-sigma-factor
MPSDLSDADVASRAAAGDSQAEAEMCRRMAPRLRLYGMRHLRSGAAADDLVQQVLLTTLEALRAGKLRDYEKLPHFVLGMARMTVLELRRGAKRRGALLEIYGAILVPEAPIEPEVDRERLGRCLQSLKERDRSVVMLTFYDDRAGSDVARFLGVSEANVRVIRHRAIRQLRGCMEGEVA
>NZ_CP015136.1|WP_157898939.1|2269231_2270134_+|SgcJ/EcaC-family-oxidoreductase
MIAQDRKPQLNTRADQPFRFLGVPTTLRATHETTGGAFGLVENSAMPPGFGSPYHVHHREDESFYVIEGEVAFVVDGQWHYAGPGSFVHGPRDIPHGFAVIGTRPARMLLLATPGGFEQFVLALRTPFDTTPEPPDMAALMAAAARHGVDILGPLPDMPDDLRGGRDDARADIDRLRATHIAALTANDAAGWTAIFADDAVQLPPVGAVNTGTAAIGAFNERFMAMFAVSSFNITPMGLEVHGDVAIEHGDYNIVLTPHGAPAGMSDSGKYITTYRRNDAGAWLITRDGWTSTLRPPADA
>NZ_CP015136.1|WP_157898938.1|2268460_2268961_-|DinB-family-protein
MTPQDLHALVDYNYWATHRLLAAVDALTPEQFVRDLASSFRSVRDTLTHVHDAEWIWLSRLHGVSPTSRLPLDRFEDCAALRAGWAETQGGLRTYVDGLDDAGVQRVVEYRLLNGSSSADRAWHLVQHVVNHGTYHRGQVTTMLRQLGAAPPLPLDLVAYYRERRG
>NZ_CP015136.1|WP_110170492.1|2267612_2268230_-|gluconate-2-dehydrogenase-subunit-3-family-protein
MTDHGRALPLVWHPDSASAAGASAGTPGGITRRSALQGLAAGLGLAAGTPADAHESHHPLAAHVAQRPTKPAITVAKKPQFFDPHQFATLTLVSELIVPGSVASGSPAWIDEVLAIEHEDLRLTFISALAAVDAAARDQHGSTFRALPATQQPALLESLTTPVATLKSWIAGAHYSSEAGMKELGFTGNVFFESFPACTHAEGHE
>NZ_CP015136.1|WP_110170491.1|2265718_2267398_-|GMC-family-oxidoreductase
MQTDPAGQHFDVVIVGSGASGGWAAKRLTEAGLRVAVLEAGRALSDADYKEHVQPPQLKYRGRTKTPFEHTQPQQSQSYAVREWNADWYVNDIEEPYLDDSDPKFLWVRPRVVGGRMNIWGRGCLRMSDIDFKAASHDGVGVDWPITYAEIKPYYDLVEEYVGVSGMKEGLAQYPDGPFQPPMGLTCNEMAVRSRVKKAFGYTVTQGRTANLTKPINGRQACHYCGPCEHGCVTHSYFNSAFTTMRDAVATGRCTLVTGAMAYKVLMDPNTRRARGVLYIDRTTRQPREIFGRAVALCAQTLESVRMLFNSATRQDSNGLANSSGVLGKYLMTHFAGAGASGDLPDLVEQPTMAGANRPCGLLTPRFRNLPGGPRTDGFVRGYGLSTYVGAGFNFAAPGIGEAYKRAIAQPRPATLSFAGFGECLPYEDNTCAVDKDTLDAFGIPVVRLRITPRDNERALHRDMATHAAEILDRIGATNIRQSHGMRGQAHEVGAARMGTDPKASVLTPFLQTHDVGNLFVMDGSSFPSSSWQNPTLTIMALAVRSTHFLLEQLRTRSL
>NZ_CP015136.1|WP_110170490.1|2265107_2265629_+|hypothetical-protein
MSAIDDKYTQLGGPGGFLGRPFDAGAGSGEMDTADRRGRFRDFERGTIYWTATTGAHEVHGDIRLKWARLGGGRSFLGYPLTDETGTPNRRGRFNHFEHGSIYWTPTTGAHEVHGAIRDKWASLGWERSRLGFPTSDEKAVPNSRGRISEFEGGVIVWTPEGGAQVRVRIDDP
>NZ_CP015136.1|WP_110170489.1|2263793_2264987_-|esterase
MRTATARLVSASVIACLGASPAFAQQAHVNLDWAPHRNIGGLVPFGANVVSPDVDQQRRVTFRVKAPRAQEVQLSAPTIAAALGRAESSWPFTKGADGTWTLTLGPVPQNIYVYKFLVDGVPVVDPNNTLGGFGNQPGYSTLVVHGEGPAYYDARPVPHGTITRHVYQSTVTDGERELFVYTPPAYDRTKVYPVLYLLGGSGEIASGWWLDGRAGFIADNLLAEGRAVPMVIAMPNNQVVHRSDPQHADKTFTLFDRELRTEIMPLVESQYRVQADRHGRAIAGLSMGGRHAQLVGFKALDLFASFGILSAGDPASETSTPQFLTDPDINTKVDYLLVGLGTHEDQPTNRSVVFHQILDRHAIRHEYAIGGNGAHDWATWRYLLYTHLLPNLFKPRK
>NZ_CP015136.1|WP_110170488.1|2262845_2263784_-|hypothetical-protein
MDLRTFWINLGWLVVLIVTIATPLALDAVGRLTYFSSLVFWGIPLLYLWPVFQSLTATGTGRRRRALRWSAGTIAVMGVALDLVLGHLTFRFPGCDAAPGTSPYVLCVPGLGGLVPVEELLFYVMGPIVIVLTYACADERWLGRYHSGDDRLDYALIRLSPHLVALAAIAAVTAIVLWRANGTFPTYFAFLTAGAILPAMFLYRAVGHLTNWQGLAVTTLYVLLTSIIWEVTLAIPRDWWGYEPAGMIGLVIGAWSRGTAIFPVEAAVVWLTAPLSCILIYEFANAFFHHSGSTRAALFGDTAASGHRTRRP
>NZ_CP015136.1|WP_110170487.1|2261774_2262713_-|HD-domain-containing-protein
MRKPAILLSALAVITALHFSLHMGGHTQHVVHVTLRTAYLFPVIVAAVWYGRRGGLLTAAAAIVVFVPHVLLDWANQQMENVSQIASGAVFLLVGWVVGALVDQRDRERERAAAAVQRARRLAIVKAIAALSAALDTRDRHTARHSEEVARVALQLGHARGLSADRLEVLRLAALMHDVGKIGVPDDVLFKTDSLTPEERDVIQQHPVTAGGILEAIDGTRDIADIVVAHHECPDGSGYPLGLRADQIPVEAAILSVADVFVALTEQRPYKEARSPEAALAWMQSVSGSKLDAESVRVLADVVMETPPPGSV
>NZ_CP015136.1|WP_110174606.1|2271692_2272727_-|glycoside-hydrolase-family-43-protein
MLALGVALAAAAQTSSGPWFLDQPLLPGIYTADPSAHVFGGRLYLYPSHDIDAGVPADDLGSHFAMRDYHVLSMDRIGGAVKDHGVALDIASVPWAKRQMWAPDAAERGGQYYLYFPAKDARDVFRIGVAVSSNPAGPFKADPEPIDGAFSIDPAVFRDADGAAYLYFGGIWGGQLQRWASGAYQAKDAYPAPGAPALMPKVARLRDDMRHLAEPVRDVIINDAEGRPLTYGDNTRRFFEATWVHRYNGKYYLSYSTGDTHFLVYATGDSPYGPFTYRGRIMEPVLGWTTHHSIVESEGKWYLFYHDAQLSKGQTHLRNVKVTPLVHRPDGTIETIVPYRAGGR
>NZ_CP015136.1|WP_110170496.1|2272972_2273983_-|amidohydrolase-family-protein
MTPPLRHVTRRLACAAICLAPAAVSYAQNTSRQAPPVLDVHFHAMDDSGPTAVPMCPNTSRFTASDPATKEATNGWAQEECTPKLYPAAKGEYIKDVVADMERLNVTAVVFGTPESVRKWIDAAPGRVIPGTGFEAAGARVPLDQLRTSFAKDGFKVMGEIGLQYQGVSPSDMSVDQYFALAEELDIPVAIHMGTGGSGRSNVTRSTFRGSMGNPLLLEELLARHPKLRVQVMHAGYPMIDNMLTLLQANSHVYVDLAGLIWSYPLKEVNRYIERLVDGGFGDRVMFGTDQLVWPKLMAYSISIIQNADYLTPEQKRDILYNNAARFLRIDPKSAK
>NZ_CP015136.1|WP_110170497.1|2274015_2275587_+|TldD/PmbA-family-protein
MSPSFSRREFIASGTALAAGIVVPGWAEIFQSGPDVDAVRAEAADEALAQAAKLGASYADIRVNRYRRESIATRERQVQNVSRSASYGMGLRVLVNGAWGFAASHRVDAATARTLAGQAVAIAKANAALAARKVVLASADTVKATWTSAFTRDPFDVPIDTKLAFLMKLNETALAVPGVSFVSSQLLLVDEHKYFASSEGSRITQRLVRTYPQFTTTAADRARGDFQTRPVVDRAKLVGYEYVEDYPWLQDAEQAGHEVVEKLKAAPVTPGRYDIVVDPSQLFLCIHESVGHSTELDRALGYEANMAGTSFLKPGDAGTRRFGATIVNLVADRSQPGGLATTGYDDEGVKADKWSLVRGGMFVDWQTTRELAPLVGQQRSHGCLHSDNWASVPFPRMPNVSLQSASTEVTRDELFSGIKRGLFIEGRGVSSIDQQRYNFQFGGAVIREIRDGRLGAMVKDAAYQSRTPEFWASCDGIGGPASYRLWGTSADGKGEPGQTNAVSHGCPPARFRQVNVLNTAGSS
>NZ_CP015136.1|WP_110170498.1|2275603_2276935_+|TldD/PmbA-family-protein
MLSRDEALTLCETVLAHARAAGAEDAVVSVASEVAAHARFADNRVTTSGRSEDLTITVTVWVDKRRGATSGNDASAAALGQLAGEAVQIARISPVHREYVPTLGPLEYPDSRGFVDATADVDVAARAVALQDVLRTCREASVSGAGVHTTNASATAVATANGNRRYFRASEAACSITARTEDGTGSGYYAGDHFDVRQVDAAQIARQAVEKAVRSRDPKPIEPGTYPVILEAQAVADLMGFLVGALDARSADEGRSAFSAKDGKTRLGESMFDTRLSLHSDPMHAELPGIPATDEGIPAERITLIRNGVLERLTYPRFWAADRKQTPTPGPTNFIVESATPLTPLPEMIKGLARGLLISRFWYVRLVDPRTIVLTGLTRDGLWWVEDGVIQRPVRNLRFNQSVLAMLAPWNVEAIGPSVRRSPFMVPPLRVGAFTFTSISDAI
>NZ_CP015136.1|WP_110170499.1|2277089_2277461_+|VOC-family-protein
MARHNPVGWFEIYVQDADRARKFYEAVFEVTLQRLPGPDIEMWAFGMDPAAPGASGALVKMPGVPSGGSTMVYFSCEDCAVEGGRVAGAGGKVHRDKMSIGQYGFVVLAVDTEGNMFGLHSIK
>NZ_CP015136.1|WP_110170500.1|2277635_2278535_-|N-acetylmuramic-acid-6-phosphate-etherase
MSDLPITEQENERSRGLDTLTIEDTLALINDEDHGVPTAVRRQLPIIAQAVEGIVGRLRRGGRLIYVGTGTSGRLGVLDASECPPTYGVPAELVQGLIAGGYDACHRAVEASEDDHDAGASDLATRGVTAADAVIGIAASGRTPYTVGAVEHARALGAFTVAIACVPGSAITLAAEVAIVPVVGPEVVAGSTRMKAGTAQKLVLNMISTTAMIQLGYVRGNRMTNMRARNSKLQARAVRILQSETGLDDAAATSALEAAGGDVATAVVMIRTGCAREAAGEALLRASGVIERAIASLCD
>NZ_CP015136.1|WP_110170501.1|2278543_2280100_-|winged-helix-turn-helix-domain-containing-protein
MDAANPEVFAFGAYRLDTGERHLLRGSEEIPLEPKVFDTLLVLVRHAGRLVGKDALMSAVWPDTHVEEGNLTRNVSMLRRALGTDAQANIETVPKYGYRFVGDVTRLTVTVEPALLYPEPPVTTTGLPTPEALLVQPPGLATPRQPWSTLALLLLVVGGSVTFVGLTRGMPDDPSARSGRPDASIADAPSSTAEPLELYLKGRHYLNTLSDESIARAASYFRRALEVNPDYAPAHAGLAEYYATIAAVGTTARMSPAEAYPLAKASALKALSLDEAIPGAYTALALVAMDYEWDHDGADRAFRRAIALAPQHVNAHHWYSHFLVTQGRFEESLEESRRALSLDPLDIPMNYHLGFHYYYARQYLDAERQLRQTLMLDSSSGDANSLLGIGLAQQGRHQEGIAAMQRGMALGGLDVRGAIVAALARAGRRAESDALLAEVLEEGRHRYVSPYELARAHAGRGEIDKAFGRLEQACDDRAADVRHLGVDPGFDGLRADPRFVRILERVGLAAVPGAVARK
>NZ_CP015136.1|WP_110170502.1|2280261_2281242_+|SMP-30/gluconolactonase/LRE-family-protein
MYPTTLPARSILTATTLALTVTLGATSSAFARQDARPDARVYALEPSTHGNPEGVAYDPRSGTFFVGTIGDGTIYRASLDDTVARVFIPGTDGGQATGLKVWRDRLYVAGGATGQLRVYEIATGQLLATVDTGEGGLLNDLAITNTGDVYVTDSFRPYLWHATAEQVEAGGGVPQAIPVEPEIAYDPFAFNLNGIVSLEDGQRLIVGHSGTGELFRIDVDADAPLGRTIQRIDVEPLFSDGLLLDKGQLVVVTFYPAPTLTFVRLDADAGSGVVVGQLTHPSITDPSTVARARNSYLVVNADFLTSTPPFTVTALPRNAAAGESEP
>NZ_CP015136.1|WP_110170503.1|2281497_2282007_+|ATP-binding-protein
MERTPKLFFLCGKMAAGKSTLARMLAEQGDAILLASDEWLGRLYPVEIVDIPAFMKYSTRLNETLTPHICTLLGRGLSVVLDFPGNTRRQRAWFRQLLDASGVDHELHVIDASDAVCKRQLHARSAGFPEGTRWTTDAEFDAITAYFDPPSPDEGFTIIRHEAGAGGQE
>NZ_CP015136.1|WP_110170504.1|2282003_2282798_+|hypothetical-protein
MTRVDWSRVLAVLIVATLERVLAEELIPRAARAGAAVYVSVGQHENEQLRDGLRRFADALRSAGAGGGPAWTSADLQDEDHSSTPQRSLHDALEARYQEYRFPFFENLSELDGAGGLQALEAHYRRASTRFGYDSPPPEARLVAVGRIFLTEGRHDDVVRLARAYAKPYPVMAERLVNQVGYDQLTRGQVPAALRTFKDNVDAFPHSPNAYDSLGDAHCRAGDTVSAIASYQQAARVAEASTPQHPRLATYQKKARTGCEPSSR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015136_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_3

2378761-2378870

Orphan

Consensus_repeat	Method
CGTTCGGCGTTCGACGTTCGACGTTCGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_3

>merge|NZ_CP015136|3|2378761-2378870|CRISPRCasFinder
GCGCCGACGTTCGGCGTTCGACGTTCGACGTTCGTCGCGCTGCCCTCAGGTCCCCGGTGCCCGAAACCCGGTGCCCGGCCGAAGGCGGCGTTCGGCGTTCGACGTTCAAC

>NZ_CP015136|3|3|2378761-2378870|CRISPRCasFinder
GCGCCGACGTTCGGCGTTCGACGTTCGAC	GTTCGTCGCGCTGCCCTCAGGTCCCCGGTGCCCGAAACCCGGTGCCCGGCCG
AAGGCGGCGTTCGGCGTTCGACGTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_157898956.1\|2380303_2381158_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP015136.1\|WP_110170572.1\|2370585_2372724_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP015136.1\|WP_110170581.1\|2386809_2387607_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379240
NZ_CP015136.1\|WP_110170576.1\|2378887_2380225_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP015136.1\|WP_110170574.1\|2375802_2377092_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_CP015136.1\|WP_169812038.1\|2374524_2375304_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|99785
NZ_CP015136.1\|WP_110170568.1\|2365034_2365319_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110174612.1\|2382695_2384237_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|236461
NZ_CP015136.1\|WP_110170569.1\|2365335_2366433_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380659
NZ_CP015136.1\|WP_110170570.1\|2366429_2367215_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|369777
NZ_CP015136.1\|WP_110170583.1\|2389073_2389688_-\|non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP015136.1\|WP_110170582.1\|2387759_2388707_+\|type-I-pantothenate-kinase	unknown	unknown	gnl\|CDD\|235466
NZ_CP015136.1\|WP_110170578.1\|2381175_2382699_-\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP015136.1\|WP_157898958.1\|2388717_2388891_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110170579.1\|2384436_2385783_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP015136.1\|WP_110170567.1\|2364344_2364878_+\|YcbK-family-protein	unknown	unknown	gnl\|CDD\|283577
NZ_CP015136.1\|WP_110170571.1\|2367871_2370589_+\|phosphoesterase	unknown	unknown	gnl\|CDD\|293737
NZ_CP015136.1\|WP_110170575.1\|2377049_2378570_-\|DUF1080-domain-containing-protein	unknown	unknown	gnl\|CDD\|368908
NZ_CP015136.1\|WP_162271346.1\|2363274_2364228_+\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|225536
NZ_CP015136.1\|WP_157898957.1\|2385970_2386741_+\|two-pore-domain-potassium-channel-family-protein	unknown	unknown	gnl\|CDD\|366146

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_157898956.1\|2380303_2381158_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.70347e-22
NZ_CP015136.1\|WP_110170572.1\|2370585_2372724_-\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	0.0012724
NZ_CP015136.1\|WP_110170581.1\|2386809_2387607_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379240	pfam13527, Acetyltransf_9, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	5.7918e-10
NZ_CP015136.1\|WP_110170576.1\|2378887_2380225_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.09669e-30
NZ_CP015136.1\|WP_110170574.1\|2375802_2377092_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.32204e-74
NZ_CP015136.1\|WP_169812038.1\|2374524_2375304_+\|hypothetical-protein	gnl\|CDD\|99785	cd06188, NADH_quinone_reductase, Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase, and has NADH and FAD binding sites. (Na+-NQR) is distinct from H+-translocating NADH:quinone oxidoreductases and noncoupled NADH:quinone oxidoreductases. The NAD(P) binding domain of ferredoxin reductase-like proteins catalyze electron transfer between an NAD(P)-binding domain of the alpha/beta class and a discrete (usually N-terminal) domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal domain of this group typically contains an iron-sulfur cluster binding domain.	5.58778e-105
NZ_CP015136.1\|WP_110174612.1\|2382695_2384237_-\|AAA-family-ATPase	gnl\|CDD\|236461	PRK09302, PRK09302, circadian clock protein KaiC; Reviewed.	4.55317e-60
NZ_CP015136.1\|WP_110170569.1\|2365335_2366433_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380659	cd20004, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate-binding protein such as CUT2. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	3.7259e-118
NZ_CP015136.1\|WP_110170570.1\|2366429_2367215_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	3.73509e-26
NZ_CP015136.1\|WP_110170583.1\|2389073_2389688_-\|non-canonical-purine-NTP-pyrophosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	5.47128e-73
NZ_CP015136.1\|WP_110170582.1\|2387759_2388707_+\|type-I-pantothenate-kinase	gnl\|CDD\|235466	PRK05439, PRK05439, pantothenate kinase; Provisional.	0
NZ_CP015136.1\|WP_110170578.1\|2381175_2382699_-\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	1.941e-46
NZ_CP015136.1\|WP_110170579.1\|2384436_2385783_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.80343e-40
NZ_CP015136.1\|WP_110170567.1\|2364344_2364878_+\|YcbK-family-protein	gnl\|CDD\|283577	pfam05951, Peptidase_M15_2, Bacterial protein of unknown function (DUF882). This family consists of a series of hypothetical bacterial proteins of unknown function.	2.97796e-64
NZ_CP015136.1\|WP_110170571.1\|2367871_2370589_+\|phosphoesterase	gnl\|CDD\|293737	cd16013, AcpA, acid phosphatase A. Acid phosphatase A catalyzes the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at low pH. AcpA hydrolyzes a variety of substrates, including p-nitrophenylphosphate (pNPP), p-nitrophenylphosphorylcholine (pNPPC), peptides containing phosphotyrosine, inositol phosphates, AMP, ATP, fructose 1,6-bisphosphate, glucose and fructose 6-phosphates, NADP, and ribose 5-phosphate. AcpA is distinct from histidine ACPs and purple ACPs, as well as class A, B, and C bacterial nonspecific ACPs.	9.17705e-13
NZ_CP015136.1\|WP_110170575.1\|2377049_2378570_-\|DUF1080-domain-containing-protein	gnl\|CDD\|368908	pfam06439, DUF1080, Domain of Unknown Function (DUF1080). This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. However, the structure surrounding the active site differs from that of the endo-1,3-1,4-beta glucanase.	3.36458e-48
NZ_CP015136.1\|WP_162271346.1\|2363274_2364228_+\|L,D-transpeptidase-family-protein	gnl\|CDD\|225536	COG2989, COG2989, Uncharacterized protein conserved in bacteria [Function unknown].	3.7226e-84
NZ_CP015136.1\|WP_157898957.1\|2385970_2386741_+\|two-pore-domain-potassium-channel-family-protein	gnl\|CDD\|366146	pfam00520, Ion_trans, Ion transport protein. This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.	3.20154e-12

>NZ_CP015136.1|WP_110170575.1|2377049_2378570_-|DUF1080-domain-containing-protein
MTALLALVLLLSSAPAFAGRAAFADASAPRPEFFVFDNGVGRGSWTPEQQAQTLKELGYDGISYNYTTPEDLARWQKAFAAVDLKIYGLYLYTYIDRAEAFDPRLPEAVAMLKGTPTTIWITVQKPKSASADDEARAVAVVQRVADLAKPHGVQVALYGHAGFYVEHALDSARVVAKAHRSNLGATINLCHEYMSGVGDKVDAAVEAVAAKATRVSINGVDVAAKNYITRLDQGDFDLVAYLRKLRAAGYTGPIGLQAYNVPGDPRQNLAANIATWRRIAAQLDEGAAGATAQNVLTAKEKADGWKLLFDGKTTTGWKGFAKQSFPTEGWVVEAGTIKGLGRKGGDIITTTAYGDFEFAWDWRLSFQGNSGVKYFVDETRGNAGGAIGHEYQTIDDDNYTVMSLTERQKTGAWYDVIPPAKTAARPVGEWNSSRLVVRGTTVEHWLNGTLVLAYDMTSVEAARGIATSKFKDVKGFADKIRTPILLQDHDTVVWFRNLKVRELGSR
>NZ_CP015136.1|WP_110170574.1|2375802_2377092_-|MFS-transporter
MVPQPEGPRARLSVSHVRWTVVALLFFAVTINYVDRAVIGVLKPVLDQALGWDQRDYGWMVTAFQAAYAIGYAVSGRLLDRFGIRLGFSVAVALWSLAAMAHGAMSTVLGFSVARAALGLAEGGTLPAAVKGVSEWFPREQRAFATGMFNAGSNVGAITCPVVVPWLAGRWGWQGAFVATGAIGFVWLAVWLWLYRAPDQHPLVNAEELAYIRKDPPEPPHPHLPWAALLGKPQTWAFMIGMMASSPVWWFYIFWVPDFLNKQFGLGLTQSSLPLVVIFTVASAGGVGGGWLSSKLLRAGWTVNAARKTALLACSACILPVFITPLVPVTHVWWAVAIVTLAAAAHCGYAANLFTLVSDTVPRQAVSSVVGIGGMAGSIAGMFFAQLVARVLYATHDNFVVPFAIAACTYSLALLAIHLLLPRLEPMTI
>NZ_CP015136.1|WP_169812038.1|2374524_2375304_+|hypothetical-protein
MTKAGNGNRLPSYLPGQYMQLHVPAYGALRFEDIVVDEPYASVWRAHHLFDLGAGNDLEMKRNYSIATNPASAARELRFNVRIATPPAGQDCDAGAGSSWVWRLKAGDTVQASGPFGSFLVPDGEHELVYVGGGAGMAPIRSHLSYLFDTLRTTRRVTYWYGARSRQEAFYLDYFRELEAQFPNFHFHLALSAPLQGDAWDGPTGLIHDVLRREHLARHAAPDAAAYFVCGPPVMVQATREMLRHEFGVAADAIIADEF
>NZ_CP015136.1|WP_110170572.1|2370585_2372724_-|hypothetical-protein
MTTRARLRRDLSWPVPAADLQDLDVIEIVHGEDGQVLWRVDDRPAAAPQDCREALMKRRHLDEPADAAVTPGIQFADQALTPPPSGEWPDAAESPFPAIESSEIPELSELPVLSELPAPPEFPELTTLLAVTHTDLPDMPLVLQTPELPDAATALPLRETPDLPDLGVVPQVEAAEDTPDVAELPEFSEIPELAALPELAAVLALTDMPDVPLVLQATERLDGATAPPLRENAEPVDVPVVPQVEAAEDTPDVAELPEFSEIPELAALPELAAVLALTDMPDVPLVLQAAELLDVATALPQHKHADVPTVPQFEAAEDTPQAAQWPELPELPQQAAAHAEVPDPPPVLQAPDVLDMAMALQLRENLEFLDVPVLHVFQAPPDVHALLAAHALPEPHEVPQVAALPPIVELPRATGQPEAREVVLTREWPQVVEFIEATPESEWPPAAEPWAIPEEPAMDAPEIPVLDETHAVPFPGRPHLAAAHMRAWVIAARAALARSRVEPVERFALVGGGMLMGVLFAIVGGPPVPATANVAATESPPHLTRPAPAETGAVGSSTVLQRMVPASRLVKAPVSPFPVTIPAETFPGIGLPVTPSAPRPRPQAAPAVLGAIQRYAVAYNRQDARATKAVWPSADRQALVKTFTGLREQRLTLLSCTTAVTGDSAIASCLGTRRYRPRVGDSSTRIQQGRWRFALQRTGGTWLIASVDAPNG
>NZ_CP015136.1|WP_110170571.1|2367871_2370589_+|phosphoesterase
MTGRLRRLLPPALVIVLAGLGLWLVVSPAGVTRPTILEPPGRNQQASITGTEATLVNGRRVTPAGTVLRTQSYNWGLAISPDQSRAALLRADSIEVVDLLPPHDIRRYPPRGTKVPALGTGTYMGIAFAPDGKSIFYGNANEGQILRLDLASGEIVATIDIDDGGIEDSFVGDFVLTRDGRTLVAVDQFNFRLVTVDVASGQVRQSVRVGRHPFAVALSPDERTAWVSNVGMFEYPLIPGVTPDNRATAGITFPAYGVPSAEAEQGTVAEGQSIPGLGPLNHPDAMSVFKVDLASGQVTQKIHTGYLVGADRDDIRTVGGASPGALAVARDRVYVSNATNDTITVLDAGTGKRLADIALNVPGLETLRGVLPFSVVLSPDQSRLYVACAGLNAVAVIDVHTRAIEGYVPAGWFAALVAVSVDGQRLYVSSAKGLGSGRNAGPGFDDPGRGLHPGDIMQGTLQIVETPRGTTLSDGTRQVIDNTYAAREVPPLLARTLPYANSRFEGPIKHIVFVVKENRTYDQVFGQRRDARGNPSGATLGLGVRVASKDGRRVLPRVDVTPNHHALADRFAISDNFYCDADQSNTGHRWVVGVYPNEWVEVNARSRIEARPFGPAPGRRNVNGSSAVVNPEDYNEAGALWEHLARHGVPFFNFGFGAEMPQSIEAQMHKETGIRMTVSFPLPKPLFDRSSRKYPTFNMAIPDQYRMDMFEEELRTRWESGVESFPSLVTIVLPNDHMTSEHPEDGYPFRESYVADNDLALGRLVERLSHSRWWDDMLIIVTEDDPQGGTDSVDAHRSLLMLISPWVKRGYVSPVLASFGSLMRLQFTLLGLPPLNQFDGAATLIDDVFSDSPDITPYDARPSDLRLFDPQLAFKPFARRFNWRGLATSRAMDDPDDMRRDLDDD
>NZ_CP015136.1|WP_110170570.1|2366429_2367215_-|methyltransferase-domain-containing-protein
MDDAEAARYWDDNAEAWTTLSRAGYDEYRDGLNTPAFLAMLPDVRGREGLDVGCGEGYNTRQLAARGARMTGIDLSRGFLRHAVDAERLDPRGIGYVGASAAHVPYADGSFDFVTAFMSLMDMPGLERVLSEMRRVLRPGGFLQASIEHPCFATPHRRNLRGPDGRTYALEVGDYFNRLDGTVTEWTFSAAPPEVKTTVRRFRIPRFTRPLGEWINMFIDAGFAIERIEEPRPDDEAVRAYPRLQDAQVVAFFLHVRVRRI
>NZ_CP015136.1|WP_110170569.1|2365335_2366433_+|substrate-binding-domain-containing-protein
MERDVMASVWHMPSIRGDGYTRGMPPSTGVGRGACLAARRWGVTLMLALLAMAGCGGRDARNASAITIGFVPKGSTHEHWKRVRIGAEKAAAEFSAAGTPVSVIWKAPMREDDREQQLQVVEGFTSQGVSGIVLAPLDSSALRRPVEEAARVGIPTVIFDSALAPPNRIVSYVSTDNGKGGHLAGRRMGELLKGTGTVLMLRYQEGSAATEEREQGFLDQLHSAYPGITVISSDQYAGPTRDTAKRASENLLNRFASKIDGIFTSNESATGGMLLALQDIGRAGHVAFVGFDFSSSFLEPLARGEINGFIAQHPVNMGYLSVKTMVEHLQGKAVPAVVDTGVILVTADNVAEASVQAVINPPDAR
>NZ_CP015136.1|WP_110170568.1|2365034_2365319_+|hypothetical-protein
MFVVRETFTAKPGQASALARQLKAAVSLNPVAKTRVLTDYIARFNTVVIETEVEDLAVFDQQMAEYMSRADIRAAMEGYAERYLTGTREVYRVV
>NZ_CP015136.1|WP_110170567.1|2364344_2364878_+|YcbK-family-protein
MDRRHFLRAVATAVPVLAFPGLASGTPVTVGPRVLTFAHLHTAEKLEVEYMDGVRYLPQALSAVNHLLRDFRTGDVHDIDPALLDLLHALHASTGSRRPFEIISGYRSPLTNAMLRSHGGGVASGSLHMEGKAIDIRLADVPLESLRDAALDLRRGGVGYYAASNFVHVDTGRVRRW
>NZ_CP015136.1|WP_162271346.1|2363274_2364228_+|L,D-transpeptidase-family-protein
MGDLVVDVHETHTHYTGGIVEAVKRFQVRHGLEADGVIGAGTIRAINVPLAGRVRQIELAMERMRWLPKLGEGQNIFVNVANFRLWANDPRTRDEPLRMNVVVGQSLDHQTPLFVEQLEYIVFRPFWNPPRRILVDEILPKARRDPGYLARNQYEIVASGADTAPALAPSPDNIDKVQQGRLTLRQRPGPSNSLGLAKFIFPNDEDVYMHGTPSRGGFAKARRDLSHGCVRLEDPAALATWALRDQPEWTRARIDEAMNGDTPVRVTLRRPMTVVLFYDTVHVSRQGVVYFMDDIYGHDQLLDAALKQGYPYPVQSR
>NZ_CP015136.1|WP_110170576.1|2378887_2380225_-|Gfo/Idh/MocA-family-oxidoreductase
MHRRTFLQSAGLIAAGAAAPTILPARVFGAQAPSGRVNLAFIGTGRQAQGMNLPEFMAVPGVQVVAVCDVDSWRVGQAKALVESTYAKQASSGRYTGCDTHRDFREVLARKDVDAVMISTPDHWHVPMAMMALRAGKDVSLEKPITRHIADGRRLANAVKQHGRVFRVDSEFRSLERFHRAVELVRNGYLGTLKTIRVSSPKEEFPEEAAVEAPVPAELDYEMWLGPAPKVPYMQKRVHNPRDLKGRPGWFRSTMYADGMLTNWGAHLVDICQWANGTERTGPIEVQATGRYHADPVWDVLETFEARYRFANGVEMFYTMDQPQIRFEGDKGWLQVHYSKSAAHPEFLEASAAGILAATIPADGVRFPLRSERVDFIEAVRTRRPTMEDAEVGQRTISLCHLAHIGVKRQGAKLAWDPATERFPTDAEANTHLEGPAGRGKWGTE
>NZ_CP015136.1|WP_157898956.1|2380303_2381158_+|helix-turn-helix-domain-containing-protein
MPGAERRHLYLPARDRSFWTAEGEQLPLLYLAWGARDFHRQPIPVSRHEGWVCVLIEEGAPTMVVRRQAVRMPAGTLALVGPDCPFGWKGATSGASKFRMWMWRDFTGTMGPADLRASIVSRPLARHERQPFLHLHDLCRREVLRAAGPAGTYLEGCRILFDTTIQRELLDRPAGGEDGSDTVALARSWMRAHLDSHEPIARLCDYLNVSQSTLYRVFAAAEGMSPLSWFHEARMARAHELLVSSALSVKEVAHVLGYEHGNDLSRAFRRRFGETPTTRRARQS
>NZ_CP015136.1|WP_110170578.1|2381175_2382699_-|response-regulator
MNDARVVVWAPGRDGRLTCDVLRDRGFSCLLTRAWSDVLFALHGGTGTLLVAGELLTGDIYSSLEGFLTAQPAWSDLPIIVVGADGEDLSAPHPLQALGNVSLLPRPLVLPTLTSTVQAALRARARQYQVRDLLWQRDEAARRKDEFLAMLAHELRNPLAPLRTGLQVLRLSPSAAMAERMHHLMERQLTNVTRLVDDLLDVSRLTRGVVTLKLRPVDVRDVVHQACEAASAAARETGLTLARDVPQTPLVVMADPVRLDQMVGNLLTNAIRFTQAGGRIDVRAERTGGHVRVGVRDTGQGIAASQLPRVFDLFAQSDRPIDRGQGGLGIGLTVVRSLAELHGGAASIASEGEGRGTEARIDLPLHAETIEAAVTPAEVPHEVEGRRVVIIEDNADAAEALAVYLQRIGHDVTVARDGRSGLDAVQRHRPHAIICDIGLPELDGYEVARRLLAQGLPSQCLLIAVTGYGDVVGRARTRAAGFSHHLTKPADPAALARLIEGTDAACA
>NZ_CP015136.1|WP_110174612.1|2382695_2384237_-|AAA-family-ATPase
MAELAWGHRVSVTNGAGEARFGERVSTGVPGLDEVLGGGLPQGHMYLVEGESGAGKTTLGMQFLLEGHRRGERTLWISLSEAERELELIAGSHGWSLSGIAVANPASPARELDPQQQYSFFSPGDVELDDIRNAVVAAVEHVQPTRVVFDPFSDIRHLSRDVLRYRRQVLSLRELFASYDCTAILMQEGTRTGEGDLQAEALAHGYITLQQDTADYGSQRRRLRVHKMRGIPFRDGYHDFAIRTGGLEVYPRLVAADHVEPMPETTLSSDVPELDALIGGGLRRGSSTLLMGPAGVGKSIIATQYAVAAARQGETVALFIFDETARSFLDRSARLGLDLRDLAESGHVQLRQVDAAEFSAGQFTHMVVRAVSDDGASVVVIDSLSGFLSAMPEERFLSSHLHELLTYLGHRNVVTILTLAQHGILGSQLSSPLDISYLADTVLLLRYFEAFGAVRRAISVVKKRTGNHEVLVRELGVNDSGLHIGPPLADFEGVLTGNPRFTGIQADLSRDAR
>NZ_CP015136.1|WP_110170579.1|2384436_2385783_-|Gfo/Idh/MocA-family-oxidoreductase
MPHFLDRRSFLKSASAGLGAGFVIPAVASAAPAIRVQPGAAADRVRVALMGVNSRGGQLARAFLNTPGAAITVICDVDSRAAARAIAAVSALGGGTPRAIPDIRKVLESPDVDALVVAAPDHWHAPAAIMAMQAGKHVYVEKPCSHNAAEGELLVETQKRTGKVVQMGNQRRSWPNVQKAIGLVHGGRIGRVYNARTWYANSRPTIGAGKPAPVPEWLDFDMWQGPAPRRPFVDNLVHYEWHWRWHWGTGESANNGTHMFDLARWGLQVEHPTRVTSAGGRYHFSDDWEFPDTQVVTLEYPDRKMVSWESMSANGYKPQGNGVGVTFHGEQGSLMIDGDGYTVYDLKGTVVEDVKTDPGAVTSQVGPSVRLDSLHTANFLDGIRGKATLFTPIAGGHVSTMMAHLGNIAWKTGHALTCDPATGRIVGDADAMKLWAREYEPGWAPRTS
>NZ_CP015136.1|WP_157898957.1|2385970_2386741_+|two-pore-domain-potassium-channel-family-protein
MPLTMYRPQSPAYQLFMLFLCVATLLGVAIQVVFHPVAQVRGVLQVADTIACGLFFIDFLVTLRRAPDKWRYMYTWGWLDLVSSIPVFDLARWGRAARLARLLRLLRGIKASMVLTEVVLLRRRQSAFLAAGLALLLVVVSASVLILTVEDSTQSNIRSTEDALWWATTTLTTVGYGDRYPVTTEGRIIAAGVMAAGVGLVGVLSGLLAAWFMEPVRTAEQREEDLFELRTLRQEMSELRRLLDQRAGVRDTPEAT
>NZ_CP015136.1|WP_110170581.1|2386809_2387607_+|GNAT-family-N-acetyltransferase
MPHTPASLVEESNRLFQHAWTYFVRRMPAGATTRVPGLLIANGRSGLSFMNIAIPTSPVADEADLRARIGLAASHFRKDGVHWLMVISDDVLPGALRERLTNVCVDAGLQYALPMFGMVADVLLDPVRPLPALDMQVVTTAALREAVGDINAAGYAMPGELFRPVTTLPEFWTDMIGVVGIAKGIPVATASVALIDEVAYVALVATDPDHQRKGYAEAVMRRALEESAEAWGERRTVLHATAAGQPVYRRMGYADVVRFDAFAGV
>NZ_CP015136.1|WP_110170582.1|2387759_2388707_+|type-I-pantothenate-kinase
MSTAATALSRFLTFDRAAWAHLRDSTPLTLSESDVTALRGLNDALSMDEVVQIYLPLSRLLNLYVGASQGLYRTTQTFLGNDGAQVPFIIGLAGSVAVGKSTTARILQALLSRWPNHPSVDLVTTDGFLFPNAVLESRGLMKRKGFPESYDRARLVRFLADVKAGVAEVHAPVYSHQRYDIVPGLVQTVRQPDIVIVEGLNVLQAPPHQRDTDHLFASDFFDFSIYVDADERDIEQWYVARFVRLVETVFQDPDSYFHRYASLDVPQARATAAHIWAEINAPNLRENIQPTRMRAHLILTKDARHVVEQVQLRRV
>NZ_CP015136.1|WP_157898958.1|2388717_2388891_-|hypothetical-protein
MTRPLWFGIAMFSAFGSIYAGLFGLKWLQYPLIALAVLAIAMAFRAPTLPPPEDPRK
>NZ_CP015136.1|WP_110170583.1|2389073_2389688_-|non-canonical-purine-NTP-pyrophosphatase
MSVSVRLLVATSNPGKVRELVALFADVPCTLLSLQDLPSPIAPPDETGETCTDNARLKATAYARAAGLPCLAEDSGFEVAALDGLPGVRSARVPGADDAERNAWVYAQLDARGSRESSARFVSVLALAHSTGDIAHVAEGDVSGEIAPEPRGSNGFGYDPMLFHPPLGRTFAELTQEEKADVSHRGRAARLMHDWIREHIGEIR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015136_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_4

3473854-3473951

Orphan

Consensus_repeat	Method
CGACCTGAAGGTCGGCGGCTACGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_4

>merge|NZ_CP015136|4|3473854-3473951|CRISPRCasFinder
CGACCTGAAGGTCGGCGGCTACGACGGAATGTCCCGTCGACCAAGGTCGACGGCTACACTTCGCGATGTCCGTCGACCTGAACGTCGGCGGCTACGAC

>NZ_CP015136|4|4|3473854-3473951|CRISPRCasFinder
CGACCTGAAGGTCGGCGGCTACGAC	GGAATGTCCCGTCGACCAAGGTCGACGGCTACACTTCGCGATGTCCGT
CGACCTGAACGTCGGCGGCTACGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_110171362.1\|3470578_3472174_-\|ribonuclease-Y	unknown	unknown	gnl\|CDD\|237177
NZ_CP015136.1\|WP_110171356.1\|3463113_3464871_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP015136.1\|WP_110171369.1\|3478733_3478931_-\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676
NZ_CP015136.1\|WP_157899185.1\|3473997_3474345_-\|cell-division-protein-ZapA	unknown	unknown	gnl\|CDD\|377476
NZ_CP015136.1\|WP_110171372.1\|3482032_3483211_-\|PDZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|223864
NZ_CP015136.1\|WP_157899184.1\|3469403_3470573_-\|thiamine-phosphate-kinase	unknown	unknown	gnl\|CDD\|100030
NZ_CP015136.1\|WP_110171358.1\|3466767_3467766_+\|ADP-glyceromanno-heptose-6-epimerase	unknown	unknown	gnl\|CDD\|187559
NZ_CP015136.1\|WP_110171373.1\|3483328_3484513_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|227278
NZ_CP015136.1\|WP_110171363.1\|3472599_3473799_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP015136.1\|WP_110171368.1\|3478225_3478594_-\|50S-ribosomal-protein-L20	unknown	unknown	gnl\|CDD\|179959
NZ_CP015136.1\|WP_110171360.1\|3468768_3469404_-\|3D-domain-containing-protein	unknown	unknown	gnl\|CDD\|270620
NZ_CP015136.1\|WP_110171366.1\|3474674_3476897_-\|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234804
NZ_CP015136.1\|WP_157899186.1\|3474352_3474634_-\|cell-division-protein-ZapB	unknown	unknown	gnl\|CDD\|274765
NZ_CP015136.1\|WP_110171357.1\|3464870_3466775_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP015136.1\|WP_110171371.1\|3479865_3481821_-\|threonine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234752
NZ_CP015136.1\|WP_110171370.1\|3479086_3479788_-\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
NZ_CP015136.1\|WP_110171367.1\|3476893_3477979_-\|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|234780
NZ_CP015136.1\|WP_110171355.1\|3462230_3463052_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110171359.1\|3468025_3468769_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP015136.1\|WP_110171354.1\|3459481_3462208_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_110171362.1\|3470578_3472174_-\|ribonuclease-Y	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
NZ_CP015136.1\|WP_110171356.1\|3463113_3464871_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	9.0948e-174
NZ_CP015136.1\|WP_110171369.1\|3478733_3478931_-\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	1.25718e-22
NZ_CP015136.1\|WP_157899185.1\|3473997_3474345_-\|cell-division-protein-ZapA	gnl\|CDD\|377476	pfam05164, ZapA, Cell division protein ZapA. ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerization and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring.	7.0529e-12
NZ_CP015136.1\|WP_110171372.1\|3482032_3483211_-\|PDZ-domain-containing-protein	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	8.81466e-60
NZ_CP015136.1\|WP_157899184.1\|3469403_3470573_-\|thiamine-phosphate-kinase	gnl\|CDD\|100030	cd02194, ThiL, ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the conversion of this intermediate to thiamine pyrophosphate. The N-terminal domain of ThiL binds ATP and is related to the ATP-binding domains of hydrogen expression/formation protein HypE, the AIR synthases, FGAM synthase and selenophosphate synthetase (SelD).	8.36681e-92
NZ_CP015136.1\|WP_110171366.1\|3474674_3476897_-\|phenylalanine--tRNA-ligase-subunit-beta	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NZ_CP015136.1\|WP_110171373.1\|3483328_3484513_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	3.75936e-39
NZ_CP015136.1\|WP_110171363.1\|3472599_3473799_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.44116e-29
NZ_CP015136.1\|WP_110171368.1\|3478225_3478594_-\|50S-ribosomal-protein-L20	gnl\|CDD\|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	3.09186e-53
NZ_CP015136.1\|WP_110171360.1\|3468768_3469404_-\|3D-domain-containing-protein	gnl\|CDD\|270620	cd14667, 3D_containing_proteins, Non-mltA associated 3D domain containing proteins, named for 3 conserved aspartate residues. This family contains the 3D domain, named for its 3 conserved aspartates, including similar uncharacterized proteins. These proteins contain the critical active site aspartate of mltA-like lytic transglycosylases where the 3D domain forms a larger domain with the N-terminal region. This domain is also found in conjunction with numerous other domains such as the Escherichia coli MltA, a membrane-bound lytic transglycosylase comprised of 2 domains separated by a large groove, where the peptidoglycan strand binds. Domain A is made up of an N-terminal and a C-terminal portion, corresponding to the 3D domain and Domain B is inserted within the linear sequence of domain A. MltA is distinct from other bacterial LTs, which are similar to each other. Escherichia coli peptidoglycan lytic transglycosylase (LT) initiates cell wall recycling in response to damage, during bacterial fission, and cleaves peptidoglycan (PG) to create functional spaces in its wall. PG chains (also known as murein), the major components of the bacterial cell wall, are comprised of alternating beta-1-4-linked N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), and lytic transglycosylases cleave this beta-1-4 bond.	3.36831e-21
NZ_CP015136.1\|WP_157899186.1\|3474352_3474634_-\|cell-division-protein-ZapB	gnl\|CDD\|274765	TIGR03752, conj_TIGR03752, integrating conjugative element protein, PFL_4705 family. Members of this protein family are found occasionally on plasmids such as the Pseudomonas putida toluene catabolic TOL plasmid pWWO_p085. Usually, however, they are found on the bacterial main chromosome in regions flanked by markers of conjugative transfer and/or transposition. [Mobile and extrachromosomal element functions, Plasmid functions].	0.000190731
NZ_CP015136.1\|WP_110171357.1\|3464870_3466775_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP015136.1\|WP_110171371.1\|3479865_3481821_-\|threonine--tRNA-ligase	gnl\|CDD\|234752	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed.	0
NZ_CP015136.1\|WP_110171370.1\|3479086_3479788_-\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	2.2593e-84
NZ_CP015136.1\|WP_110171367.1\|3476893_3477979_-\|phenylalanine--tRNA-ligase-subunit-alpha	gnl\|CDD\|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CP015136.1\|WP_110171358.1\|3466767_3467766_+\|ADP-glyceromanno-heptose-6-epimerase	gnl\|CDD\|187559	cd05248, ADP_GME_SDR_e, ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs. This subgroup contains ADP-L-glycero-D-mannoheptose 6-epimerase, an extended SDR, which catalyzes the NAD-dependent interconversion of ADP-D-glycero-D-mannoheptose and ADP-L-glycero-D-mannoheptose. This subgroup has the canonical active site tetrad and NAD(P)-binding motif. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.47806e-148
NZ_CP015136.1\|WP_110171359.1\|3468025_3468769_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.01557e-19

>NZ_CP015136.1|WP_110171363.1|3472599_3473799_+|Gfo/Idh/MocA-family-oxidoreductase
MQRRRFLAVTLGCCAALPRIAAARQSAPGQTLRVALIGHSGQGDYGHGVDRVWAQIRGARVVAIADADPAGLAAAGQRTGGVRGFADYRAMLAEVKPDVVAVCPRHAHEHRDMIVGALDGGARGVYVEKPFVRTCAEADQVVALARRTGTSLAVAHRNRYHPALPVLQKYLADGTLGRILEIRARGKEDQRGGGQDLWVLGGHLFNVATLFTGAPTACSATIQQQGHPATRSDVHEGDEGVGLIAGDEVHARFDTQRGIPIFYDSKKALGSAAAGFGLQIFCERGVVDLRMDIEPLVHVREGHPFIPDTTPRAWIPLTSAGPGVPETVPGLSKRILDHVAAVEDLLACLGSGREPLCGPTPASETVEMTQAVFASFAAGGPVTMPLTTRTWPLTREPIV
>NZ_CP015136.1|WP_110171362.1|3470578_3472174_-|ribonuclease-Y
MGQWTSLEVIGLALDGIAALALVLWVVWARKRLAADTAHAREQAAQIIASADREALARVKEAELAGKEHAHALLVEAERAGREIQDAARSTSRNAAEQLRAASERTAALLQREQDLARRQEDLLERQAAVVAIDAQAREQLAQADARNVGVLAELQRVGSLTSDEARAELVRQIEQDARRDAAHLVKRLEAEAREQAAGKARQLITEAIQRSAAEHAIETTVSVVDLPSDDMKGRIIGREGRNIRALEQATGVELIVDDTPGAIILSSFDPFRREVAREVIERLIADGRIHPARIEEVVEKVKADLEESVRRDGEAAAFELGLHDVHPELLRLMGRLRFRTSYGQNVLSHSKEVAWLAGIMARELGLDAQVAVRAAFLHDIGKAIDREMEGTHLAIGLDALRKHGERQPVLDAVAAHHMDIDWPSLEAMIVQAADAISAARPGARRDILESYVKRLEKLEDIACSFKGVAKSFALQAGREIRILVQSEQVSDEDAVWLSKDIARRIENELEYPGQIKVTVIRETRAVEIAR
>NZ_CP015136.1|WP_157899184.1|3469403_3470573_-|thiamine-phosphate-kinase
MAAGLPGWDHDVSATCAQVGEHALIRWIASAVGSASSADVLLGIGDDAAVVVPRRNHVDVLTTDVQVDGVHFTRAFCGAADVGHRALHVNLSDVAAMGAQPRVALLSLGLPADLEARWVADLVTGLVTAARAARVQLVGGNISRAPMLFVDVTVSGAAKPRHLLRRSGARPGDELYVSGTVGAAAAGLAWLQSAIGRAGSPSRPSPQGAETDAAEPGDGRFGERALPSAIEAALTRYRRPEARVSLGLQVGRNKAASACIDTSDGLADALRQLAGASGVGVRVDAAAVPVDPAVTELALRTNEDRDALAWSGGEDYELLFAVPRRARRRFLHASGRKGLPPVTRIGMCTREADCLIVQADGRESPLPGGFEHFSSVDSVAGGRIPEAGA
>NZ_CP015136.1|WP_110171360.1|3468768_3469404_-|3D-domain-containing-protein
MLLTRSLRRRIVVAVGAALGFVLLYESPIFDSEYMPRAFRRVARSETPVMQPGPPDPEDVAAPAPGLTVRFRATAYCKGTTTASGAGIQTGIAAADPDLLPVGSVIRAEGLGSRYNGIYTILDTGPRVKGRQIDVYMWSCNEALAFGRRTTRLQVMRLGWNPRTSTPERVGTEFRRREAEMTADAPARPPATTPPPQSAPAPGIPPPTPEP
>NZ_CP015136.1|WP_110171359.1|3468025_3468769_-|class-I-SAM-dependent-methyltransferase
MDLLLEATRRAEQEHFWFKGFRAFVAPLVASAVAAHPPRRLLDCGCGTGVNLPMLAQYGSAYGFDLTWTGLKFAKDHGTHRLTQASVLHVPFRDDSFDVVTCFDVLQCFPPYIAAQVLAEFHRILAPGGHLVMNVAALESLRGDHAVLAEEAHRYERGELHAMLEATGFHVARLTFTNASLFPIMLGARWWQRLRGLKAIEDAHDDFTVPSAVVNDTLTGLLKCEAALLRRLDMPIGSSLLALAQKR
>NZ_CP015136.1|WP_110171358.1|3466767_3467766_+|ADP-glyceromanno-heptose-6-epimerase
MPELIDLERARVLVTGGAGFIGSALVWGLNSRGASRVVIADRLGTSTKWRNLRALRFEDYVEADVLRERLDTGRLGDFDLVLHMGACSATTEQDASYLARNNYEFSKDLCQWALSHGAAFLYASSAATYGDGSASMDDDAAGIERLRPLNMYGYSKLLFDRWARDQALLSRVAGLRFFNVFGPNEDHKGDMRSVVHKACAQVREEGRVQLFRSHHPEYRDGEQRRDFVYVKDVVDMTLHVAARGATGLFNIGSGHAQTWLDLVRPIFGALQVPEQIDFVDMPAALRGTYQYHTQADISRLRATGYAAPPTPLSAAVAEYVADYLVPGRQLGD
>NZ_CP015136.1|WP_110171357.1|3464870_3466775_+|ABC-transporter-ATP-binding-protein
MSAHDDEILGKAYDSRLMRRLMGYLRPYKVRAAFALVAIVAGVAFSLAQPVLVKRAIDQYIASGDLAGVGTVALLYLGTLVGAFVAEFVQTTTLQMLGQRIMYDMRRQVFDHLQRLDLAYYDRNPVGRLMTRVTSDVDAINDLFTSGVVSVFGDVLSLLGIIVVLVSLDWRLALLTFCVLPLILMVTQWFRRNVRESYREVRTWVARLNAFLQENLTGMSTVQLFRREERAFADFDHVNSEHRDANLRSIYYYAVFYPAIELIGALSTALIVWFGGGWVLTGTLTIGTLVAFIQYAQRFFRPISDMSEKFNLLQAAMASSERLFGLLDTPVIITDPSLALGAEPALGPGPSAFEKPRGADSTADGRRPMADNAKRSRGAGRLVVEDVSFAYTPGVEVLKHVSFTVEPGQRIGIVGATGSGKSTLINLLLRFYDVGSGRILLDGRDIRELPLAQLRSHFALVLQDVYLFSGTIAGNIRLGRPDIDDSRVHEAAEAVHAAAFIRDLPHGYDTPVAERGATLSVGQKQLLSFARALAFDPQILVLDEATSSVDTETEMLIRDALHVLMEGRTTIAIAHRLSTIQDMDQILVLHRGELREAGTHQELLALRGIYHRLYQLQYQSHAPAATLQHSHGDA
>NZ_CP015136.1|WP_110171356.1|3463113_3464871_+|ABC-transporter-ATP-binding-protein
MLAALRRLLPYLGRSRRPMLLGLCCAIVANLFALLTPWVLKYAVDDLTAAVTRAKLGRYALALLAISAGGGIFRYFMRRLIIGVSRRVEYDLRSDFFSQLQRFPREYFDKARTGDLMSRASADLGAVRMMAGPAAMYAVSTGVLAIAAVGMMLWIDTRLTLLIVTFTPLVSLMVKYFGQAIHTRFERIQAQLAEISAITQEALAGVRVVRAYGQEAAERAKFLAASDEYVARNRKLILLQASFFPSMTFGFGLAIVAFLYLGGREVIRGSLTLGEFVAFNGYLGQLAWPLIAFGWVTNMFQRGLASWQRMLEVFDTAPSIVDGPTAQRLPEPVRGRLRVRHLTFAYGTGPVVLHDIDLHVPAGSTLAIVGATGSGKSSLVHLLVRMYDPPPGTVFIDGHDVRDVRLEDLRRAIAFVPQETFLFSTTLEDNIAFGAHAMPDAQRRERVEEAAAIARLDKDVVQFAEGYQTRVGERGLTLSGGQKQRTAIARALMTAAPVLVFDDALSAVDTYTEEEILSRLRTVTADRTTIIVAHRISAVRHADQIIVLDEGRIIERGTHDSLAFAGGPYSELVRQQQLEAELAVS
>NZ_CP015136.1|WP_110171355.1|3462230_3463052_-|hypothetical-protein
MKVRRILESAGAASALLLLMSAPAAAQYPPNQSDPATGEKYNVEVAFGLWNPTPEIVFSSEQFGITGSEISLSNDLDVLQKTFRDFRLVLRPARKHKFRVEYIPIKYDIDSLLTRSVVFNGIVYSVGLPVQGEFKWDAWRFGYEYDFIYRDRGFLGVIAEAKYTHVSAELSAVGINEFSEAKAPIPAIGLVGRGYLMPNLAVTGEFTAFRLPDNEDRDYGGRYYDFDIYSTLNFSNNFGVTGGYRRLTLGYQAENDFGDFQMKGFYVMGVARF
>NZ_CP015136.1|WP_110171354.1|3459481_3462208_+|hypothetical-protein
MAVLVPLVTVAALAIAGWLASGIVTVQSLAAPSRIGLLSPPQTIIVVLLPLLALAALVSRRDRRTSPAATHGEPAATHQGPAATRLATLAVLLAPIVLPWLPLPLPAALLVWTGPLALAWWFASVAYTYADAFRATWAALRLRPGFGGQVGERALPRLIWSPSRAPLAAAAITGMALVAAAWRMGPQHPKGDEPDYLIITQSLLLDHDLQIENNHARADYAIYHRAPLPPSYLARGTDGAIYSVHAPGLPALLVPGFAVAGYRGAVATLILIAMAGAWLAWWTAWQLTQDVVASWVGTLATVGSAPFFLHGAAIFPDAPASVFASLAVAVLVAAQGRPDRGARLPIVSTCAASLALGLLPWLHTRYAILSIGFGAAMCLQIAARRDWRALTAFMTPASLLAASWFGFFFVVYGTANPSAPYGAYTQMALAHLLPGLPGLLFDQQFGLLASAPVLMVVLVAMRRTLRETTPGTWWVALLVVSLALLYTCVVGAYRMWWGGLSAPARFLVPLILPLAPFIALGWHSLQTRASRHMVVAMLVTSLALTALLVYVDHGALAYNMRDGRARWARWVSPLIDLSGALPAAHRDAPPIVLRDALIWLIGFAVAWVLWRTLERRGRLTPLVPLVTLAALLPAASAMVWLCHGVGGLAPARSQVLYLARRASAPADVLIAITRPHVERTRTGFIVELDSRRAPSASDYTVLRLDTLPAGRYRLLTDVRAPGARFGVTLGDARTTRFIADLDASAGHASLAFDLALPVENVVVKGSREAAEGTGRTWVLADEVSPPPAVPPATRAHPMGGSVWLLPEADVYAEPGGVWLGGDADITLGLPSSLPMEVNLRAGAADVAVAWSATDNGEARLSAGETRTVTMVPRHGRLRLLTRGGFRPSQVSPGNKDQRYLGAWISAPR
>NZ_CP015136.1|WP_157899185.1|3473997_3474345_-|cell-division-protein-ZapA
MNVTPIVDDETPLGDQDPPNHVVMVDIQGLRYPVRSALDPSYVHKLARYVDVTMDAASTAVPIGESTKLAVLAALNIADECFRGRDDESRIAAELVEKAGELERLIDAVLNKHST
>NZ_CP015136.1|WP_157899186.1|3474352_3474634_-|cell-division-protein-ZapB
MSNTATATAADLAVVERLDEKIRQLITLVEKSRAEATKLRTDNDRLGKEVDALQAQLSDAAGVSTELQAMREERDQVRTRVADMLAQLDALQM
>NZ_CP015136.1|WP_110171366.1|3474674_3476897_-|phenylalanine--tRNA-ligase-subunit-beta
MKILVSWLKEYVDVPVPIDQLAKDLTMRGFEVASVEPVNGDPDDAVIDFEVTANRPDCLSVLGMAREVAVKYGLALRSPVSAFSIGSSAFDARVPGTRNPAPAFAAGFGAASPDAIRVTVERPDLCPLYCAALVDVSIGPSPAWLAERLTLSGVRSINNIVDVTNYVLLELNQPLHAFDFDTIGDRHLVVRTARAGETLTTLDGVTRTLADDMLVIADAGTAQAVAGVMGGGATEIGPTTRTIALESAYFEPTQVRRTRRRLNLSTEASYRFERGVDPGMPARALRRAVELIVEIGAGTPRDGEVIVGTPSSTARSVRLRWSRIWRVLGMDVAPAEVEQILTLLGFHFRPIEDGGLRRKASSDGRTGSPLGAEALAEAASPAHDHPSPEWNVTVPGWRGDVTREEDLIEEIARCAGYERLPVTFPALAAPPAKTAPRLVRDARVRDVLVGAGFAEAVTFTFIERAAAVPFDAAPIAIANPLSELFAVLRPSVVPGVVDSLSHNRRREQHDIRLFEVGTRFTRTHGETRSVAIAWTGAAAAEHWSGSGRMVDLYDVLGVLQRVAETLRVRVDVEADDHPALLTGRAARLVAMHGNTRVDVGWVGQLSPSLGEARGLPAADAVLVAELDLDLAAPDYDPDRQPVMQALPRHPSVVRDLSIVLPADLPAVRVRGTIHASAPPTLVSVREFDRYQGKSLPDGKVSLSLRLTFRAAERTLTDAEVQHATDAILAALAADHGATLR
>NZ_CP015136.1|WP_110171367.1|3476893_3477979_-|phenylalanine--tRNA-ligase-subunit-alpha
MPDLSTSVSALRAEFDTALGAVTSAADLQAVRDRFLGRKQGLVTALYAEIGNAPADQKREIGRLANELKQAVEAGLEARKAVLGRAAIRTPGLDLTLAPRPLPVGSRHPLNAMRERIERIFVRMGYEILDGPEAEDDWHNFEALNMPADHPARDAQDTLYLEAPFVQGTRATGAPGAGVTLRPATLLRTHTSAMQIRYMERHAPPVRIIAPGRVYRRDNLDLTHTPMFQQVEALVVGEQVTMADLKGTLLGFAREFFDPKTPIMFKPSFFPYTEPSAEVFVGCQSCFGSGCSMCKRTGWIEIGGSGMVHPSVFEAVGIDPERYTGFAFGMGIERLALLAHRVDDIRAFYENDLRFLEQFAS
>NZ_CP015136.1|WP_110171368.1|3478225_3478594_-|50S-ribosomal-protein-L20
MPRVKRGTVRRAKREKLLTLAKGYYANKSKLYRFAKEAVDRALKSAFVGRRRKKRDFRRLWIVRINAAARQQGISYSQFIAGLSRAGVTVDRKMLAELAVSEPSAFAALTSRAKDALKQQNA
>NZ_CP015136.1|WP_110171369.1|3478733_3478931_-|50S-ribosomal-protein-L35
MPKLKTHKGASKRFKRTASGKFLRGSAFKRHILTSKTTKRKRGLRGTVLVSAQDQGKLELMLPYK
>NZ_CP015136.1|WP_110171370.1|3479086_3479788_-|translation-initiation-factor-IF-3
MRGPRRDDRVRINERIRVREVRVIDEAGQQLGIMAPAQAVALAKSKGLDLVEVAATAVPPVCRITDYGKYQYNEQKKQRQARKHQKTIEVKEVKFRPKVDLHDYDFKKRNISRFLHEGDKVKAVVFFRGREIAHPEIGRRILERLIAELTEIAVAENLPRMEGNTMHTILSGRPGIKKVEKPSKPEREPRPEVEEDDTEMTAEELAAAAQAVADEDAAGTAPVVETPAERPAE
>NZ_CP015136.1|WP_110171371.1|3479865_3481821_-|threonine--tRNA-ligase
MTPVVLTLPDGSTRSVAAGTPVRDVAADVSPRLAKAALAARVDDQVVDLSYPLTQDARVQILTADGPDALKVYRHSTAHLLAAAVTKLFPGTQCGIGPVIEEPPGFYYDFVVQRPFVPEDLEKIEAEMRRLAQADEIFERQMWPRDEAMAFFGGRGEPLKVQLIEENTQGQSEVSVYTIKDRETFVDFCRGPHVPSTGKLKAFKLTTTSSAYWKGDAKNQPMQRVYGTAFFSDKDLQAHLARLEEAKKRDHRKVGKELGLFMFHPWAPGAAFWLHKGTVLYNGLAEYMRKVLYPAGYEEVKTPIIFNKALWETSGHWHHYRENMFVLEGDEGEAMALKAMNCPGHMLVFASQVRSYKDLPIRFHEQTALHRNEASGVLGGLTRVRQFSQDDAHCFVMQEQIGDEVQRLLALVQQVYGDLGLTFEVKLSTRPEQYLGQRETWDHAESQLKLALEGAGQAYTLNEGDGAFYGPKVDFDVTDAIGRKWQCATIQLDYQIPERFDLKYVGADNAEHRPVVIHRAIFGSFERFIALLIEHFAGAFPLWLAPLQAVVLPIADRHAAYAAQVQVELKAGGLRVGLDDRQEKIGYKIREAQLQKVPYMLVVGDKEVAEGTVSVRSRQGGDLGSRPVREFVTDAQAEIESKGQAGQPVGV
>NZ_CP015136.1|WP_110171372.1|3482032_3483211_-|PDZ-domain-containing-protein
MTTRTRFLVLALTTPLVVFTLVGGLLGQQRTAPGAYPHLRVFDDVVSLIFGSYVEEPNPGTVLDGAMLGLAEGLDPDSSYLDAAQVALLEGVRTAETGSTGLSLTRQYYLRVVASRDGSPAAQAGLHTGDYIRAIDGKSTRHMSLHEGERLLRGPAGSKVTLTVLRGSQTDTHEVPLSRVAALPADVTQRIAAPGVGLVRITAFSDQTPTQLKRAVGELTSKGATQVLIDLRHTAEGDPALGAETARLFVKAGTLGIREARGQGQQKTEARAGDGSLTLPITVLTTNGTSQAAEVFTAALLDNDRAKSVGERTLGRAGSQKLVKLPDGSGLWLTYARWLTPKGTAIHGTGLVPTVPVAEPDREFGAPATAEDPILDKALESVAAKAPAKAAA
>NZ_CP015136.1|WP_110171373.1|3483328_3484513_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MRVPLLLALLAAQLPTLQQPSPTAPAAGTSAPAELVQAAEAAKAQQATKERIAALTREADVLKRQSVSMLDQVRRLDVERDLERAREVQARQALSVLEADLASLTSRQATLRSTLEGERPAIAARLRRLQRLGRVGYARIAWNATSARDVGRAARLMNYLAKDDGRRLQAYARTAGELGETEARLTQRREEARSLEAEARVRRAAAEAAYVKKRELLASLENESEQRERWLAELVAARARLDASMTGRAPVPAPTQVLRVPFTTRRRALPWPVEGNITGRFGRQRDARFGTSTVSNGVTIASTIGSAVRALHPGSVVFAGAFTGFGQLVIVDHGQQSYSLYGYLSGLRVQRGAAVEGGAIVGEVGDAPDGKAALYLEVRVDGRPVDPVLWLQQR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015136_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_5

4165115-4165202

Orphan

Consensus_repeat	Method
GGACGGCTCGGAGAGCCGTCCCTACCAACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_5

>merge|NZ_CP015136|5|4165115-4165202|CRISPRCasFinder
GGACGGCTCGGAGAGCCGTCCCTACCAACGCTGATGCAGATGGACCGATCGGATGCACGGACGGCTCGGAGAGCCGTCCCTACCAACG

>NZ_CP015136|5|5|4165115-4165202|CRISPRCasFinder
GGACGGCTCGGAGAGCCGTCCCTACCAACG	CTGATGCAGATGGACCGATCGGATGCAC
GGACGGCTCGGAGAGCCGTCCCTACCAACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_110171861.1\|4159952_4161545_+\|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl\|CDD\|273267
NZ_CP015136.1\|WP_110171863.1\|4162340_4163015_+\|DNA-repair-protein-RadC	unknown	unknown	gnl\|CDD\|178801
NZ_CP015136.1\|WP_157899317.1\|4166061_4167063_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP015136.1\|WP_110171870.1\|4171935_4172880_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187566
NZ_CP015136.1\|WP_110171857.1\|4154281_4155517_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NZ_CP015136.1\|WP_110171871.1\|4172896_4174267_+\|ethanolamine-permease	unknown	unknown	gnl\|CDD\|129986
NZ_CP015136.1\|WP_110168877.1\|4175871_4177017_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NZ_CP015136.1\|WP_157899315.1\|4155513_4157499_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110171860.1\|4158668_4159118_+\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_CP015136.1\|WP_110174743.1\|4159230_4160022_+\|diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|234768
NZ_CP015136.1\|WP_110171862.1\|4161620_4162259_-\|DUF4398-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
NZ_CP015136.1\|WP_110171872.1\|4174280_4175714_+\|ethanolamine-ammonia-lyase-subunit-EutB	unknown	unknown	gnl\|CDD\|237897
NZ_CP015136.1\|WP_110171859.1\|4157641_4158520_+\|tRNA-2-thiocytidine(32)-synthetase-TtcA	unknown	unknown	gnl\|CDD\|236737
NZ_CP015136.1\|WP_110171864.1\|4163024_4165061_+\|methionine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237028
NZ_CP015136.1\|WP_110171867.1\|4167072_4169205_+\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NZ_CP015136.1\|WP_157899314.1\|4153289_4154285_+\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187539
NZ_CP015136.1\|WP_110171873.1\|4177162_4178035_+\|ethanolamine-ammonia-lyase-subunit-EutC	unknown	unknown	gnl\|CDD\|235482
NZ_CP015136.1\|WP_110171869.1\|4170829_4171435_+\|J-domain-containing-protein	unknown	unknown	gnl\|CDD\|274090
NZ_CP015136.1\|WP_110171868.1\|4169268_4170771_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP015136.1\|WP_110171874.1\|4178415_4178751_+\|helix-hairpin-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378965

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_110171861.1\|4159952_4161545_+\|DASS-family-sodium-coupled-anion-symporter	gnl\|CDD\|273267	TIGR00785, Uncharacterized_transporter_HI_0020, anion transporter. The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds].	4.23893e-69
NZ_CP015136.1\|WP_110171863.1\|4162340_4163015_+\|DNA-repair-protein-RadC	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	1.46114e-80
NZ_CP015136.1\|WP_157899317.1\|4166061_4167063_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	1.68179e-90
NZ_CP015136.1\|WP_110171870.1\|4171935_4172880_+\|SDR-family-oxidoreductase	gnl\|CDD\|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.97533e-146
NZ_CP015136.1\|WP_110171857.1\|4154281_4155517_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.47214e-58
NZ_CP015136.1\|WP_110171871.1\|4172896_4174267_+\|ethanolamine-permease	gnl\|CDD\|129986	TIGR00908, putative_ethanolamine_permease, ethanolamine permease. The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines].	1.27219e-171
NZ_CP015136.1\|WP_110168877.1\|4175871_4177017_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.44735e-15
NZ_CP015136.1\|WP_110171864.1\|4163024_4165061_+\|methionine--tRNA-ligase	gnl\|CDD\|237028	PRK12267, PRK12267, methionyl-tRNA synthetase; Reviewed.	0
NZ_CP015136.1\|WP_110171860.1\|4158668_4159118_+\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	6.83715e-74
NZ_CP015136.1\|WP_110174743.1\|4159230_4160022_+\|diaminopimelate-epimerase	gnl\|CDD\|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	2.77438e-68
NZ_CP015136.1\|WP_110171862.1\|4161620_4162259_-\|DUF4398-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.00202236
NZ_CP015136.1\|WP_110171859.1\|4157641_4158520_+\|tRNA-2-thiocytidine(32)-synthetase-TtcA	gnl\|CDD\|236737	PRK10696, PRK10696, tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional.	8.31714e-112
NZ_CP015136.1\|WP_110171872.1\|4174280_4175714_+\|ethanolamine-ammonia-lyase-subunit-EutB	gnl\|CDD\|237897	PRK15067, PRK15067, ethanolamine ammonia-lyase subunit EutB.	0
NZ_CP015136.1\|WP_110171867.1\|4167072_4169205_+\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP015136.1\|WP_157899314.1\|4153289_4154285_+\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187539	cd05228, AR_FR_like_1_SDR_e, uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs. This subgroup contains proteins of unknown function related to aldehyde reductase and flavonoid reductase of the extended SDR-type. Aldehyde reductase I (aka carbonyl reductase) is an NADP-binding SDR; it has an NADP-binding motif consensus that is slightly different from the canonical SDR form and lacks the Asn of the extended SDR active site tetrad. Aldehyde reductase I catalyzes the NADP-dependent reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate. The related flavonoid reductases act in the NADP-dependent reduction of flavonoids, ketone-containing plant secondary metabolites. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.87834e-59
NZ_CP015136.1\|WP_110171873.1\|4177162_4178035_+\|ethanolamine-ammonia-lyase-subunit-EutC	gnl\|CDD\|235482	PRK05465, PRK05465, ethanolamine ammonia-lyase subunit EutC.	1.64216e-115
NZ_CP015136.1\|WP_110171869.1\|4170829_4171435_+\|J-domain-containing-protein	gnl\|CDD\|274090	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ. This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.	2.03625e-23
NZ_CP015136.1\|WP_110171868.1\|4169268_4170771_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NZ_CP015136.1\|WP_110171874.1\|4178415_4178751_+\|helix-hairpin-helix-domain-containing-protein	gnl\|CDD\|378965	pfam12836, HHH_3, Helix-hairpin-helix motif. The HhH domain is a short DNA-binding domain.	2.37461e-27

>NZ_CP015136.1|WP_110171864.1|4163024_4165061_+|methionine--tRNA-ligase
MPRFYLTTAIDYVNSRPHLGTAYEKITADVIARFKRLSGVQTHFVMGNDEHSQNVFRRARDLGQDPLAYCDRMEQEFREVWGALDLSFDDFIRTTQPRHKAAVETIVNRIAAAGDLYQADYEGWYCVGCEAFKQEKDLVDGLCPIHRTKPDWIKERNHFFKLSAYRDRLLAHFAEHPEFLQPDVRRNEILRLLEAGLDDISISRAGQSWGIPLPTDPSSVVYVWFDALINYASAVGLGTDPALLDTWWPADLHVIGKDITRFHSVIWPAMLMSAGLPVPRQVFGHGWVHLRGEKMSKSLGTAIDPLEAAQRFGTDALRLFLTKEIPYGADGDFSYERFEERYNTDLANNLGNLVNRVAAMAVRYRRGRLTPTGSPSRLQDLAATTVREYGDAMESYALHQGVASVYRLLDATNEYLAERAPWTLAKDPANDAALDEVLFTAAESLRLATVLLGPVMPASTQAILARLGDHASIAARRLATDGAWHNGDARTVTSGEALWPRAEPRPEPSGTPVVIAIPQEKAGASSVSEDQPSVAPVPAAAPPAGSTAHVPGATPVQVSVPAPVAPAGEDGIITIDDFMKVELRVGKVLAAEAIPKSKKLLKLTVQDGPESERTILAGIAESYAPDAIVGRTIAFVANLAPRPMMGLVSHGMVLAADTDGKAQLISFETPPAPGTRVR
>NZ_CP015136.1|WP_110171863.1|4162340_4163015_+|DNA-repair-protein-RadC
MIGLAPQDRPREKLAEQGKAALGDNELLAVLLGHGAAGITALDLANRLLADLGGLRGLARVSPVELSRRRGVGPATASRLVAAIELGRRSVVRAGPARLQIAAAVDAARYLLPRFGTAEVEQGGVLLLDARHRVLHARVLTRGTADATPMHPRDVFREAALAGAAALVLFHNHPSGDPLPSTEDLQLTKRMIEAGELMGITVVDHVILGDTSYCSLRDLGKLTR
>NZ_CP015136.1|WP_110171862.1|4161620_4162259_-|DUF4398-domain-containing-protein
MSDRPGTVRTVLRAACAALVLAALSGCATPPQKEMDQAEGAIATARAAGAAQYAAAEFAAAETALQRSREAAAQRDFRQSLNHALDARERAQTAAREAADKKAVARGLAERVITAGELALATAQQRLGAEVATPLPTSRRTAPHAAAFQALQAVAASANEALQEARSQLQEQRFDDARTTAAPVQAQILAATRTFDATKAGSPPARSARRAR
>NZ_CP015136.1|WP_110171861.1|4159952_4161545_+|DASS-family-sodium-coupled-anion-symporter
MARRWGVLDGVGGGPVSRDLAGVRTLDEASRAVESYSPAEEAFNRKRRTWGLFLGPLIFGLMWLAPLPVPGPAHRLAAILAMVVVLWISEALPMAVTAMLGPILAVVFRVAPARGALAPFADPIIFLFIGSFILAEAMFVHGLDRRIAFTALASRWVGTSGTRILVVYGLVGTCISMWMSNTATTAMMFPIGLSIVAQLRRGSAGQEEALRKFATVMMLITSFGASVGGMATPVGTPPNLIGIGLIERITGTHIGFFRWMAIGVPLVLILFTILATFFVLTSTRGVHVGEAGARIVREELDRLGPMNKAQRNVCVAFGATVLLWTFPGVLAIAGLSNTSLAKAYLTSVPEGVAAMLGAMLLFVLPVHWAARKFTITWEEAARIDWGIVLLYGGGLAMGDLAFSTGLATAMGHGLTSWLPGAGPMLLTTVFTGAAILLSETTSNTASANMVVPVAIAVATASKVDPMLPALGATLGASMGFMMPISTAPNAIVYSSGHVPISAMIRYGIVLDLAGFVVIVALLGLLGPLLF
>NZ_CP015136.1|WP_110174743.1|4159230_4160022_+|diaminopimelate-epimerase
MHFWKAHAYGNDFLYAALADVVSGDLAELARHMCARTTGIGADGLILFERRPGGARMRLHNADGSIAEVSGNGVRGLAALLAHQQPSPVGTAFDIDTDAGTKHLALVSRDEQGRPVFRAAMGRPERLAQQDVPLGDETLPLATLWMGNPQAVWLVETLDTREMLRVGAALQQHPAFPDAVNLELAHVVSPGEVEILIYERGVGPTHSSGTGSCAAAVAAAAYGGAARVVDVVAPGGRQHVEWLDDGVYLTGWAEVLCQGTWLA
>NZ_CP015136.1|WP_110171860.1|4158668_4159118_+|D-tyrosyl-tRNA(Tyr)-deacylase
MRAVLQRVRSASVTVEQRIVGEIGVGFVVLLGVVVGDDAADLAYIVDRTAGLRVFPDAGGRMNVDLRAVSGALLVVSQFTIAGDCRRGRRPSWDGAAPAEEAQAWFERALAAWRALGIDVQSGIFRADMQVALVNDGPVTLLLDSRKQF
>NZ_CP015136.1|WP_110171859.1|4157641_4158520_+|tRNA-2-thiocytidine(32)-synthetase-TtcA
MPYASPLEARIAKKVARASIEHSLIEPNDRVMVGLSGGKDSWALLQILDVIGKRAPFPFTVVAVNVDSGYKDFKHGVIKRACEDRGWDIRIEHTEIGEVMDDLLEANATPCSLCARLRRGVLYRIAEEEGATKIALGHHLDDFIETLLLNLFFGGALKAMPARLVSDDQRHVVIRPLVYVSEQEALEYAMACELPIVGCCCPACGDLGLQRQRLKRLIGDLEREHPGIKSSMLKAIQNVHPRHLLDRRLNPLDVMARTGHVDGDDDGEAVSTAAHPLPVLRRTGTSGADRVS
>NZ_CP015136.1|WP_157899315.1|4155513_4157499_+|hypothetical-protein
MNMPRAARLGRLWSDPGAVATLILGALLLGFALTVQFPVVAFGFQSDEATYYSLGHSFARDWDMQFQRKDLVRVWKEFPTGPEGIFLKRGRSVHLEPQARPPFVRWVKSPDPRTDRLYYGKSFIYPLLASPFITLWGTNGFLVLHALLLTACFGAVYAFVRARSGQAAALAYAVAFLFASAAPVYFVWLTPELFNLSLVLLGLFFWAYKEVAPAAVPTATWLDRWASLLRSPWSDVIACALLGIATFSKPLNVLAAAPILWLAILRRQWGRVAIVSLAFVAATGGLFLINGISSGDMNYQGGGPDRSTFYGRFPFQTPESTFDNTGIARATDGLLTEVIFNQDALTTVLRHNLVYFLVGRHTGLVPYFFPGILTLVLFLFAGRHRREPFQWLILLALVLASVSLLIYMPFTYSGGGGPVGNRYFMGYYALFLFLVPAVITVRAAVVAAVVGGLFTAQLIANPFYSSFNPATHPKYGLFTRLPIELSLVNDLPVNVTPSRAKQPLAGNPPVLAYFIDDNAYNREGEWFWVRGESRADLILRAPARPHADGAFTSLAIDTIEVEVATGAAASVVSIDTGAERVRVAPGARSGDTVRVKMPEGFPYKAIPGQPLNRVYSISIASSEGFVPLFDEGVRDNRFLGARIRITPLYRDDRYQPPRAAH
>NZ_CP015136.1|WP_110171857.1|4154281_4155517_+|glycosyltransferase-family-4-protein
MSEKISVLHVCDHLGWAGSRMHGVKRLFAWTLPRFDKSRFDVSLVSLRQKDSSEDTLEQFGIDVTYLHKGKFDPATLTALLKVMDRKRTQVLHLHGYGATTFGRLAAAMRGTAVLLHEHANHTTTPWFQQVADTTLARYTDLAIAVSASTAEFTIRARKIPAERTKVVYLGAPLEEFGRARSGQEIAAARETLGIARGTFAIGTVTRLMPAKGNQYLIDAVRPIVDQVPEAHVYIAGEGELQAQLGAQARDLGVADRVHFLGFQRDVASVLSAFDLVVFPSLWEGTPLTSFEALAMGKPIVSTDADGLCEILRDGVDAAIVPRESGRAIADAVVALEADPARRASLGAEAQRTSRRYDIAVWVRKMERLYELMARVSKPTRRQGLLREDLSFLDAGQPSPLPGSRLPGAQP
>NZ_CP015136.1|WP_157899314.1|4153289_4154285_+|NAD-dependent-epimerase/dehydratase-family-protein
MTAALVTGVTGFTGGHLARHLVHRGITVRGLVRPRSLGRPEVATLREAGIDIASGDLTDAAAVAAACEGVDVVYHIAATYREAGQPDSAYRAINVQGVEHVIDGARAGGARRVVHCSTGGVHGHVANPPANEDAPFNPGDVYQDTKLEGEQLARAAGQAGGLEVVIARPIGIYGPGDLRFLKMFRGISRRRFPVLGAGEVFYHLTYIDDLCEGFRLCGEVPAAAGGTYILGGPRYTTLNTLVDLIAAELKVKPLPVHLPVWPFWLAGAACEAICVPLRVQPPLYRRRVDFYTKSRAFDITRARTELGFAPAVDLPEGIRRTIAWYRAQGLL
>NZ_CP015136.1|WP_157899317.1|4166061_4167063_+|polyprenyl-synthetase-family-protein
MQPSSSPSDLAQLFEPVREDLERVNQAFLRHIDSRVELIPEIGKYLQNTGGKRVRPAVMLMASRLAGGEAQSDMAVLYASVIEFIHTATLVHDDIIDDSELRRGRLAVHARWGNDVTVLLGDYLYIKSLGMALEYDRIDVLRVLCDITLKMIEGELYQLTKNGDTEITEDEHFDIIRRKTAYLFAGAARIGGMVGTITPAQEQALWDYGFNLGVAFQLVDDLLDYTADQVALGKPVGSDLREGKLTLPIILLRDRVPEQARPIIEQVVRDAEISDEAWRQLLGLLREYDIVPQVTRRAGEYVEQARRQLVSFPESRERDALLGLADYVLARDR
>NZ_CP015136.1|WP_110171867.1|4167072_4169205_+|NAD-dependent-DNA-ligase-LigA
MAAPADRIDALRAVIRHHEERYYVHDDPEVSDAEFDALVRELRELEAAHPDLVTADSPTQRVSGRPAEGFETAVHLRPMLSLDNAYSDEELEAFDERVRKGLGTEGPVHYVAELKIDGLSIAITYEDGRFARGVTRGDGVIGEDVSSNVRTIQPIPLRLKNAPDGRLEVRGEIYFPRAAFDRLNGEREAEGAPLFANPRNAAAGTLRNLDPSLVARRGLRAFFYHAVREDNVGSRGDAEAPTDGLPETHASLMESLSSWGLPVEKHWTRCAGIDAVKTFCASWAETRQQLPFDTDGIVIKVDRREERERLGFTSKFPRWATAYKFPAQQATTTLLRIEVQVGRTGAVTPLAVLAPVFLAGSTIQYATLHNEDEIRRKDIRPGDEVLLEKGGDVIPKIVKPILSTRPEGLAPFEMPAQCPVCATALERPEDEVVWRCPNPSCPARLRRSLEHFAGRRAMNIDGLGSALVDKLVALELVRDFADLYRLTVEGLADLKFEAKAREGGDEVEQGSARTPTARRFGEKSATALVTQIDNSRRNELWRLIFGLGIRHVGERGAQALAEAFGTMQAVAAANVDQLQAVSDIGPVVAASVRRFFDTPASTHLIARLEAAGLHMGEPVAEGRGPKPLEGRTIVLTGGLATMTRDEAAERLTVLGAKVAGSVSKKTSLVIAGEDAGSKLARARDLGVPIGDEDTLVHLLATPATWPFDNL
>NZ_CP015136.1|WP_110171868.1|4169268_4170771_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MSGRILVIDDEAGIRESLRMILEYEGYTCLLAATGEEGLAMARTEAPDLVFSDIKMPGLDGLEVLTRMKALDESLPVVMISGHGTVATAVEATKLGAMDFIEKPLSTERVLLTVRNAINASRLEHENRRLRGAEDARYNIVGQSPVLLQVLDAIGRAAPTNATVLVLGESGVGKELVARAIHRNSLRSRERFVQVNCAAIPEELIESELFGHEKGSFTGATDKQIGKFELADRGTIFLDEVGDMSQKTQAKVLRVLQEGEVERIGSQRTLKVDVRVIAATNKDLEAAIGEGTFREDLYFRLSVIPVHVPPLRERPDDIPLLVKHFAELFAADGGRTRRFTPEALGVLQQHRWRGNIRELKNTIERVLIMARGDVVDVQDVRQFLRVEGTPLALPPAAAVSMALTPAAPQPMPGAAVDGFAGLSTVTPPVTVGPSADEGRPAPPKPTTLREFKEQVEREFLVDKLREHGWNISRTAEVIDTPRSNLYKKLEQYEISQERDG
>NZ_CP015136.1|WP_110171869.1|4170829_4171435_+|J-domain-containing-protein
MPTNEPKSSQGDGQVYAETTDYYELLQISPNADPDTVTRVFRLLARRYHPDQPDTGNEEKFREILAAYAVLNDPEKRAHYDVNHTGIRRERWRFVAEGAPTAGDYVAEQQVRLVVLEILYSRRRTEPHKPGLSLLDLAELMGQPLEHLEFSSWYLVMKKLVVRNDQSQLQITADGVDYLEEHRRNESPRLRLTERTTLGSH
>NZ_CP015136.1|WP_110171870.1|4171935_4172880_+|SDR-family-oxidoreductase
MAFYLVTGGAGFIGSHMVEALRKRGDRVRVADSLVTGKRTNLAHVDEVELLEGDLADEAFARKAVEGVEYVLHQAAIPSVPRSVDDPITSNRANIDATLSLLVAARDAGVRRVVYAGSSSAHGNIATLPKREDMPTAPVSPYALQKLVGEQYMKMFTDLYGLSTVTIRYFNVFGPRQDPGSAYSGVISLFIRYLVEGQAPTIHGDGGQTRDFTYVANVVDGALRASQAETPVSGKVINVATGTRISLNDLFNTLKAITGAHVEPVYGPTRAGDVRDSLADITLARDLLGYRPLVGLEEGLRETVAWYASTQQPA
>NZ_CP015136.1|WP_110171871.1|4172896_4174267_+|ethanolamine-permease
MNAPGAPAPTLTRTLGTFQLWGIAVGLVISGEYFGWSYGWASAGTLGFLVSSAFVALMYATFIFSFTELTTAIPHAGGPFEYSRRAFGPIGGVVAGLATLIEFLFAPPAIALAIGAYMHVQYAWLEPRWVAVGAYGVFMALNIAGMRIAASVELVVTLVAIFELLVFMGVVAPGFSLQAFLRGGWAGRDTFSIASIGGIVAALPFAIWFFLAIEGVAMAAEEVHDPKRSIPRAYIGGIITLLVLAAGVMVFAGGVGDWTQLANINDPLPQAMKRVVGADSGWLHMLLWLGLFGLVASFHGIIIGYSRQMFALARAGYLPHVLARIHPRFHTPHVAILAGGVVGLAAVFSDGLVHIAGQTLTATIVTMSVFGAIVMYIISMASLFRLRRSQPDLPRPFRAPGYPWVPGFALACAVICLLTMVYYNPQVALWFGLMMAAGLGAYLLVRGTGETTSGAH
>NZ_CP015136.1|WP_110171872.1|4174280_4175714_+|ethanolamine-ammonia-lyase-subunit-EutB
MATYAHVIDGTRHVFDDLRTLLACATPERSGDRLAGVGAGSAVQRAAAQMALADVPLGAFLQEALVPYEADEVTRLIVDSHDAAAFAPIAHLTVGSFREWLLSDDVDSDVLARVAPGITPEMAAAVAKIMRAQDLVLAARKARVVTRFRNTIGLAGRMATRLQPNHPTDDLAGIAASVLDGLLYGSGDAVIGINPALDNVAHVVRLLEMLDAVITRYEVPTQACVLTHVTSTLRAIERGAPVDLVFQSIGGTQGTNASFGVSLSLLAEARDAALSLHRGATFAEGPGQNVMYFETGQGSALSAGAHHGCDQQTLEARAYGVARHFAPLLVNSVVGFIGPEYLYDGKQITRAGLEDHFCGKLLGLPMGVDICYTNHAEADQDDMDVLLTVLGAAGCTFIMGVPGADDVMLNYQSTSFHDALYARRVLGLRPAPEFEAWLERMAIFAPGSGARLLEHAGGLPPAFARALHLEPRSRNDV
>NZ_CP015136.1|WP_110168877.1|4175871_4177017_+|DDE-type-integrase/transposase/recombinase
MDLRVQFISEYLADRFTMTALAAQYGISRKTAYKWVARYDAAGPAALGDRSRRPHQHPAATAPALVEALLRVRRRHPQWGAKKLLALGRRQQPDAAWPSRSTVCDLLQRHGLIVPRRRRRPVPHGSHRLAPLTGPNVTWTTDFKGEFRTGDRAYCYPLTLRDGFSRYVLRCDALLSRTTAETRRCFARAFAAYGLPERIRSDNGSPFAGPGLGRLSRLNVWWMRLGIVPERTGLGRPDQNGSHEQFHRVLKAETTRPPARTARAQQERFRTFCREYNGIRPHEALDNQPPATVYQPSPRALPARVPALVYPGHWEVRRVDSNGCIAWGGAPLFLTEVLDGESVALEAVDDGVWTLHFASVSLGRVHDRTRTITALPPAQHP
>NZ_CP015136.1|WP_110171873.1|4177162_4178035_+|ethanolamine-ammonia-lyase-subunit-EutC
MPREPVIANPWSALRRFTPAHVGLGRAGVSLPTMTHLAFQLAHARARDAVHDPLDVARVRGELAALGLTTLVLRSAAVDRATYLQRPDLGRRLDEVSQRTIDALGLPYRADRFDVAFAVVDGLSSNAIHRHAAPFLREVLTALPGARTAPEQEHRNTGVQEHRSEPAVRATWSVAPVAVVEQGRVAIGDAIGEALHARLVVVLIGERPGLSSPDSLGAYLTWEPVPGRTDAERNCLSNIRPEGLDYGDAAVRLVGLLREARRRELSGVALKDEHDALPRASSSPSFLLDP
>NZ_CP015136.1|WP_110171874.1|4178415_4178751_+|helix-hairpin-helix-domain-containing-protein
MTGSMLVLLLALSHPPTPVTLPAAYAFVQDARPAAPAQSVNVNTATVAQFEALPGIGPSMAQRIVAYRDKNGPFKKLEDLMNVQGIGEKSFLKLRPLLTISGQGDAKASKN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015136_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_6

6657961-6658063

Orphan

Consensus_repeat	Method
TTTCGACATTCCGGCATTCCCGGCATTCCGGCATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_6

>merge|NZ_CP015136|6|6657961-6658063|CRISPRCasFinder
TTTCGACATTCCGGCATTCCCGGCATTCCGGCATTGGTCAATGGCTGCAATGTCGAGAGCGTGATGGCTTTCGACATTCCGGCATTCCCGGCATTCCGGCATT

>NZ_CP015136|6|6|6657961-6658063|CRISPRCasFinder
TTTCGACATTCCGGCATTCCCGGCATTCCGGCATT	GGTCAATGGCTGCAATGTCGAGAGCGTGATGGC
TTTCGACATTCCGGCATTCCCGGCATTCCGGCATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_110173827.1\|6665954_6668594_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|379297
NZ_CP015136.1\|WP_110173819.1\|6655352_6656234_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110173826.1\|6664840_6665416_-\|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl\|CDD\|273138
NZ_CP015136.1\|WP_110173820.1\|6656233_6657304_-\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100004
NZ_CP015136.1\|WP_110173818.1\|6654198_6655314_+\|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|185333
NZ_CP015136.1\|WP_157899779.1\|6650744_6651734_+\|Fpg/Nei-family-DNA-glycosylase	unknown	unknown	gnl\|CDD\|223344
NZ_CP015136.1\|WP_110173815.1\|6651992_6652448_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350222
NZ_CP015136.1\|WP_110174904.1\|6663672_6664638_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110173824.1\|6661224_6661995_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP015136.1\|WP_110173816.1\|6652456_6653605_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181651
NZ_CP015136.1\|WP_110173822.1\|6658078_6659617_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP015136.1\|WP_110173828.1\|6669732_6671046_+\|aminoacetone-oxidase-family-FAD-binding-enzyme	unknown	unknown	gnl\|CDD\|272992
NZ_CP015136.1\|WP_110174903.1\|6645870_6650547_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|137505
NZ_CP015136.1\|WP_110173821.1\|6657343_6657880_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|365914
NZ_CP015136.1\|WP_110173814.1\|6651750_6651996_+\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	unknown	unknown	gnl\|CDD\|226603
NZ_CP015136.1\|WP_157899780.1\|6653705_6654140_-\|DUF4281-domain-containing-protein	unknown	unknown	gnl\|CDD\|379473
NZ_CP015136.1\|WP_157899781.1\|6659626_6661228_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_157899782.1\|6668595_6669624_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291
NZ_CP015136.1\|WP_110173825.1\|6662211_6663366_-\|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl\|CDD\|225364
NZ_CP015136.1\|WP_110173829.1\|6671053_6671989_+\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|350614

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_110173827.1\|6665954_6668594_-\|TonB-dependent-receptor	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	4.50828e-12
NZ_CP015136.1\|WP_110173828.1\|6669732_6671046_+\|aminoacetone-oxidase-family-FAD-binding-enzyme	gnl\|CDD\|272992	TIGR00275, TIGR00275, flavoprotein, HI0933 family. The model when searched with a partial length search brings in proteins with a dinucleotide-binding motif (Rossman fold) over the initial 40 residues of the model, including oxidoreductases and dehydrogenases. Partially characterized members include an FAD-binding protein from Bacillus cereus and flavoprotein HI0933 from Haemophilus influenzae. [Unknown function, Enzymes of unknown specificity].	4.32255e-127
NZ_CP015136.1\|WP_110173826.1\|6664840_6665416_-\|pyridoxamine-5'-phosphate-oxidase	gnl\|CDD\|273138	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase. This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	4.60503e-95
NZ_CP015136.1\|WP_110173820.1\|6656233_6657304_-\|RidA-family-protein	gnl\|CDD\|100004	cd00448, YjgF_YER057c_UK114_family, YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	7.37263e-24
NZ_CP015136.1\|WP_110173818.1\|6654198_6655314_+\|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl\|CDD\|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	1.06498e-100
NZ_CP015136.1\|WP_157899779.1\|6650744_6651734_+\|Fpg/Nei-family-DNA-glycosylase	gnl\|CDD\|223344	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair].	1.67913e-47
NZ_CP015136.1\|WP_110173815.1\|6651992_6652448_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350222	cd09874, PIN_MT3492-like, VapC-like PIN domain of the hypothetical protein MT3492 of Mycobacterium tuberculosis CDC1551 and other uncharacterized, annotated PilT protein domain proteins. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis CDC1551, hypothetical protein MT3492, and similar bacterial and archaeal proteins are included in this subfamily. They are PIN domain homologs of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.33386e-33
NZ_CP015136.1\|WP_110173829.1\|6671053_6671989_+\|TraB/GumN-family-protein	gnl\|CDD\|350614	cd14789, Tiki, Tiki homology domain antagonizes Wnt function via cleavage of amino-terminal residues. Tiki is a membrane-associated metalloprotease that inhibits Wnt via the cleavage of its amino terminus, diminishing Wnt's binding to receptors. Wnt is essential in animal development and homeostasis. In xenopus, tiki is critical in head development. In human cells, TIKI inhibits Wnt-signaling, which is important in embryogenesis, homeostasis, and regeneration. Deregulation of WNT contributes to birth defects, cancer and various diseases. TIKI homology domains are part of the TraB family and are related to the Erythromycin esterase, GumN plant pathogens, RtxA toxins, and Campylobacter Jejuni heme-binding, Chan-like proteins. TraB/PrgY are identified in gut bacterium Enterococcus faecalis, but its function has not been well characterized. Plasmid-borne, TraB has been implicated in the regulation of pheromone sensitivity and specificity. Based on homology to TIKI activity, it has been proposed that TraB acts as a metalloprotease in the inactivation of mating pheromone. The TIKI/TraB family has 2 conserved GxxH motifs and conserved glutamate and arginine residues that may be catalytic.	2.43341e-61
NZ_CP015136.1\|WP_110173816.1\|6652456_6653605_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181651	PRK09105, PRK09105, pyridoxal phosphate-dependent aminotransferase.	2.53765e-77
NZ_CP015136.1\|WP_110173822.1\|6658078_6659617_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	4.94831e-87
NZ_CP015136.1\|WP_110174903.1\|6645870_6650547_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|137505	PRK09751, PRK09751, putative ATP-dependent helicase Lhr; Provisional.	0
NZ_CP015136.1\|WP_110173821.1\|6657343_6657880_+\|peptidylprolyl-isomerase	gnl\|CDD\|365914	pfam00160, Pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD. The peptidyl-prolyl cis-trans isomerases, also known as cyclophilins, share this domain of about 109 amino acids. Cyclophilins have been found in all organisms studied so far and catalyze peptidyl-prolyl isomerisation during which the peptide bond preceding proline (the peptidyl-prolyl bond) is stabilized in the cis conformation. Mammalian cyclophilin A (CypA) is a major cellular target for the immunosuppressive drug cyclosporin A (CsA). Other roles for cyclophilins may include chaperone and cell signalling function.	7.88675e-62
NZ_CP015136.1\|WP_110173814.1\|6651750_6651996_+\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	gnl\|CDD\|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	3.33625e-07
NZ_CP015136.1\|WP_157899780.1\|6653705_6654140_-\|DUF4281-domain-containing-protein	gnl\|CDD\|379473	pfam14108, DUF4281, Domain of unknown function (DUF4281). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 147 and 232 amino acids in length. There are two completely conserved residues (W and P) that may be functionally important.	1.53939e-35
NZ_CP015136.1\|WP_110173824.1\|6661224_6661995_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.34648e-85
NZ_CP015136.1\|WP_157899782.1\|6668595_6669624_-\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.00119552
NZ_CP015136.1\|WP_110173825.1\|6662211_6663366_-\|type-IV-pilus-twitching-motility-protein-PilT	gnl\|CDD\|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	6.87469e-174

>NZ_CP015136.1|WP_110173821.1|6657343_6657880_+|peptidylprolyl-isomerase
MTLPAGLYAHFNTSEGAFVARLFEEEAPKTVATFAGLADGSIEWQDPVSRQTIHRPFYDGLIFHRVIDGFVIQGGCPMGNGMGGPGFKFEDEFHPSRRHSKAGILSMANAGPGTNGSQFFVTLGPTPHLDDRHSVFGEVVSGMDVVSRIGHVPTGRGDRPVKDVVIQSLKIERVPATT
>NZ_CP015136.1|WP_110173820.1|6656233_6657304_-|RidA-family-protein
MDAFAPATTAGGLVYVSGVSAGQAALAEPVPGQVTDVLRRLDLTLLEYGSSLTRALSIHVQVRHAADFAAMNAAYARFFPSAPPVRTTVVAPPESSGALVQMSAVAAAAGAPREVLHPAGWPVSPNPYSYAARSGDLVFLAGLVPRDGRTNAVVTGDLETQIASIFCNATDVLGAAGLSLADVVSARVYLTDPAHAPAAEEYYRRHMPPPRPARSIVVAALMNPAYLVEMTFVAMAGKRALGFPDAAIPDDAIASPLMRGGSHLFLSATDGDYAPAAIDAHARTATGRLLNSLRQAGLAWADVADITLQVSDAAHAATARRAIRESMLQPLPAGTTLICGLLPHDARVQISATAVS
>NZ_CP015136.1|WP_110173819.1|6655352_6656234_-|hypothetical-protein
MASQVLRSLVVAGLAFAPGSTWQPSVVAAACAAPSAEPQITPEAVLATARLTLVRCVRGDLDGGRWRDAAERLARARQAGALLRDTDRRAWQALVVRLEATRHVDVGQWTALIDAVIPQEDVLPWAGPLVRGVAAARASWARQDPALQQRARAELVRLERLARSMGPRSEAELARLLVQGAIAGAQYERDEMQLLLEAAHDLEMRLLAGGELRAPVVLAGELEADLLRVTDRYAAASERYRVLLVEWPRRVQSRIGLADAYRRLGFAREAEETLAQARALWASADAEARALIR
>NZ_CP015136.1|WP_110173818.1|6654198_6655314_+|methylated-DNA--[protein]-cysteine-S-methyltransferase
MVTTAPAPASPRDDAAWNAVQNRDASLAGRFVFGVTTTGIYCRPGCPSPRPRRDNVRFFATTAAARTAGFRACRRCHPDDVNDASRNATGNEATARLRDTDLRLLVSHIDAALADGGRPSVASLAAAVGLAPVVFRQRLEATLGIGPRALLSGRQLARLRERLLAGDDVTDALYSAGYGSSSRLYERAQEGLGMTPGAYRRGGAGVAIGWTTAPSPLGLLLVATTIHGVCAVYLGDSEATLRDALEAEFPRATITRGVNRNEWVAAAVAVASGQALEDVPLDLQGTAFQQRVWLALRAIPRGETRTYAQLAAMIGQPTAVRAAARACATNKVSLLVPCHRVVGSDASLTGYRWGVERKRRLLDLERGQNRL
>NZ_CP015136.1|WP_157899780.1|6653705_6654140_-|DUF4281-domain-containing-protein
MTVFELSNLLVLPFWILMVLVPTWGMTRRIMASPWVVAPPALLYLVTLVPVATMVLPEVINPVQARIMSLLGTPTGTTLAWAHLVAFDLFVGRWIYLDSRSRSYSAWGVSPILVLTLLIGPVGLLMYLGARSVIGGANVASDPG
>NZ_CP015136.1|WP_110173816.1|6652456_6653605_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MALTRRGFVRRIGQATAGTVTGTMLAARGFEDLVAAHAAGQDRPEIPPGMVRLGSNENPYGPGPHVVTAVERALHDDGNRYTRLPQLLTGRLASMLSVSGGSLLVSAGSGDLLRAAVLAYVTADKPLVAATPTFETPVRVAESLRLPLRLVPLTAALSNDLDRMAEQGKGAGLVYVCNPDNPTGTFHAKTAIVEFIDKLAAMSPETVVMIDEAYFDCADDPSYGSVAMLATERRNLVVVRTFSKIHGLAGMRIGYAVAHPETLDRLRLCAGGGVVACASAAAAMASLDNIEYFRRQQVLNREARTRLTKAMTDLGYPPVPSQANFVMVDVRRDVRDFGVACRAHGVLVGRPFPPLATQARISFGTPDEMTRAIDVFHQVLRS
>NZ_CP015136.1|WP_110173815.1|6651992_6652448_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MSVPVPVDSWVWPVYLDTSAFVKLLVDETESDALNAELSAVGEVVLSDLAMTELASALARRARESLLASAEAKRLYGHAERVVSSCRVVECTPPVQRRAARLLLTSRHVSLRTLDAIHLALAIEADVSTLVTYDPRLREAAAAQGLFTAPA
>NZ_CP015136.1|WP_110173814.1|6651750_6651996_+|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin
MFVLLVTHAGVREARQDLTSLLEDVGKGREVTITDRGRPVARLVPVSVRQPFPDLARVRTATRGRQVCLADAVLGDREDRV
>NZ_CP015136.1|WP_157899779.1|6650744_6651734_+|Fpg/Nei-family-DNA-glycosylase
MPEGDTIFRAARTLHRALAGQVVTRFETQYAQIARVHDDAPITGRIVEKVESRGKHLLIYFTGTGYRVPGTGCRLLDEGGHEPGIGSRESGVVTPATTAGTRRGEVEGPLVLRTHMLMSGSWHIYRAGEAWHRSPSAARVVVGTAAFVAVGFAVPVAEFVPASALEQDETIGRLGPDLLSPDFDAGEAMARLAASGRPTVAEALLEQRSVAGIGNVFKSELLFLARLWPFVPPAEVTEAQWARMMRDAHVLLKANVIDPAEAGVLTWRGARRTTGRSNPTQRLYVYGRHGRPCRRCGTAILVRHHGEHNRSTYWCPACQAAPLNGQPGP
>NZ_CP015136.1|WP_110174903.1|6645870_6650547_+|DEAD/DEAH-box-helicase
MVRDAPVLDLFHPVVARWFRDAFSAPTAPQAQGWPVIAGGSSTLLLAPTGSGKTLTGFLWCVNRLMFEPAPDEMERCRVLYISPLKALAVDVERNLRAPLAGISRLAREEGVSHHLPQVAIRTGDTPAAERARFTRHPADILITTPESLYLLLTSNAREALRHIHTVIIDEIHAMVATKRGAHLALSLERLETIARVPIQRIGLSATQRPLDEVARFLAGAEPAPARSLQAAGCGLPEGDIHEQFAATTDDPSYRPVAIVDAGRTRQLSLRIEVPVEDMARLTQVEAITSGPAAAGPQAPSIWAAIHPRLLEVVLAHTSTLLFVNSRRLAERLAAAINELADETLVRAHHGSLAREQRVEIEDALKAGRLRGLACTSSLELGIDMGAVDLVVQIEAPPSVASGLQRIGRAGHQVDATSTGLIFPKYRGDLLACAAAVRAMREGRVEATHMPRNPLDVLAQQIVAMVAMDDWAVDDLFARVRQAAPFASLARPIFDGVLDMLSGRYPSDEFAELRPRLTWDRVAHRVTTREGAKRVAIANAGTIPDRGLYGVFLAGAPAGTARVGELDEEMVFESRVGETFLLGASSWRIEDISHDRVTVSPAPGQPGKMPFWKGDGPGRPLEFGREIGALVRQLRRDSPDQARVRLEREHDLDALAATNLVQYLAEQIEATGAVPDDRTIVIERVRDELGDWRLCLLSPLGAQVLAPWAMAVSSRLRDQFGLDVETMWADDGFVVRFPETDEPPDPQWLVPDADEVEALVIRQLGATSLFAARFRECAGRALLLPRRRPGRRAPLWQQRKRAQDLLGVAAKYGSFPILLETYRECLRDVFDIPALAETLRAVQSRQVRVVPVDTPTPSPFAASLLFGYVANYLYDGDAPLAERRAQALTIDQAQLQALLGSAELRDLLDADALDTLEAQLQCLPAEYRARTLDGVHDLLLRIGDLSTTQLRERVAADVPPDAGDRLVRARRAVWLGVAGEQRLVATEDAARYRDALGVPLPQGLPDALLVAQPHALRDLVSRYARTHGPFTTEEVAARYGLGRSTADLALKALQSEGRLLEGEFRPGGQQQEWCDSSVLTAIRRRSLAKLRHDVEPVELPVLGRLLTQWQGVTRPRRGLDALLDVVETLQGLPLAASILEREILPARLERYQPSDLDTLISAGEVVWAGVEPLGERDGRIALFLTDHVGSLWRGVLQPPSLEDLSAREQAILGALDARGALFFATLQEAAGGGFPQDTVDAIWSLVWRGLITNDTLQPLRAQVGSVGREKRSRTASRPFRSRRVAPAAAEGRWTRLAPTVAANATGWSAAMGQQLLTRYGVVTREVAGAEGLPGGFTAIHDVFRTLEESGRIRRGYFVSGVGAMQFAAPAAVDLLRALRTPPEAPEVAVLAATDPANPYGALVKWPESPDGAPGRGPTRSVGARVVLVDGHLTAWIARGMRALLVWLPEHDPERARHAEALARALPLTGTDREHRAASILLTEVNGSPSLDAPIRPFLEAAGFVATSQGLQLRDVTGTSPAMPRLRRPDHWGPDTAVNDVPEVPDEAIAPISWPRRQR
>NZ_CP015136.1|WP_110173822.1|6658078_6659617_-|response-regulator
MWIGSPSSSLAPFIPVIEHLQEAACLETADGTLAVVNEAWLALFGAAGRLSPLLEGPGATAWAPVLSAFEDPEALSARVTARRTTRVASSHETLATTDGRTLEWDHSPIAIGGNVLAHLWRFRDATHQRKLEESVRQAQRLNTVGRLAGGIAHDFNNLLTAVVGYCDLLDTQFDHGDPRRFDLHEIRNAAIRASSLTRQLLAFSRRQIMQPEVVDVGLMIGEMPKMLSRLMGEQVKVDISVPDEPLEVFADPGQIEQAIFSLAANARDAMPDGGTLGVDVRQGHLDIDRARTLDMRSGPVVTVTVWDTGTGMDDATRASAFDPFFTTRPLAQGLGLPTVYGIVRQTGGAVTLESVPGAGARVDIILPAYTDAVSEGPTSLVSVTPAVRERVGPAVVLVVEDEASVLRLVRRVLESEAMVVLSAQDAEEALLLTSQHGGVIDLLLTDVVMPGLNGLELAQRVMAERPHLRVLFMSGYADHAVVQRDIIDTGRPFLQKPFAPDRLVARVKEVLG
>NZ_CP015136.1|WP_157899781.1|6659626_6661228_-|hypothetical-protein
MTVVLARLLGVDPVQWRALVWASFITDFRQMKGSGIGIARAAAGSLGGALVSQLLYGAFCAAIIAVLPNVFASSTIYFTLLLVTLGLALLVDFTSVVLSPEDHVQLAPRPIDSRTFFVARLTSVVGFALLLTAPFALLPAVAYLFRDGGGSLAGAIASVAAAALSAVLVPLVVILVFLGLVQLIPAGRLHRALGYVQFLLSFVFIGGFFLLSRTTRAIDAVRLEKAAAIYVNPAAWFAAWIEIAERRATATDWIAAAVPLLLLVVTGLLVRSRLSLAYAERMSTMFVDRPGDTTSHRPVPHPVFGPAHHAVGLLAGAQFRTDQKFRLGVLGILPLTVIYLLAGFNDEGGPEVMRREPLLVYYAVLFFPVMLRQFLVYSESWRASWVFHAAPMPFDEIVIGLKNTVVSHFLVPYLLLVMTLLGWLYPRPPLELLTLGLVIGLLSHALLTADLLVNPSLPFSQPTRQGTRSLALLALMVPTMAIITTIPLWRPYLYATTGRIFLGVTVLLIVNVLLHETLLTRVERLSRQWACTS
>NZ_CP015136.1|WP_110173824.1|6661224_6661995_-|ABC-transporter-ATP-binding-protein
MIRVVDLHHAYGETPAVQGLSFEAGVGEVLGLLGPNGAGKSTTVKILTGLLPLQRGHVEVAGFDIASHPLDVKRRVGYVPETGALYDALTPDEYFRFISMLYRLDPGVVQPRIEEMLRMFELDSVRSARMVTFSKGMRQKVLIAAALLHAPDVIIFDEPLNGLDANAMLVFKELLRGLAAQGRTILFCSHLLDVVERLCPRIVIVDKGRAIAEGTPDAIAQRTHRPTLEQAFAVLTGARSVQDATAGVLSSLEWRA
>NZ_CP015136.1|WP_110173825.1|6662211_6663366_-|type-IV-pilus-twitching-motility-protein-PilT
MASPALPTPIVQEPPINRLFRLMVQTGASDLHLSVSVPPMVRKDGRMLAVEESAPRLTAEDIRRLLGPITPEKNRTEFERRHDTDFAYEIPGLARFRANIFMDRKGMGAVFRVIPSKILTSEELGLSPQLLQLCHLSKGLVLVTGPTGSGKSTTLCAMVDYINRVRHDHVITIEDPIEFVHDNKQCLINQREVHTHTDGFKDALRAALREDPDIVLVGEMRDLETVAIAIETAETGHLVFGTLHTSTAASTVDRIIDQFPADRQSQIRVMLSESLKGVIAQTLCRKVGGGRIAALEVLVVNTAISNLIREGKTFQIPSMMQVGKALGMQTLNDALSDLVKNKLVSPEEAYVKAVDKAGFEAMLKRMAVDTKFLTPPVMPGAKTA
>NZ_CP015136.1|WP_110174904.1|6663672_6664638_+|hypothetical-protein
MDTPAPTLVPGARVLLDAHNAYPYEGRFGDRVARALATGVPVAIEQDLIWRAGANGTGVSVVGHDVDKVVDAPTFESYFFGTIAPVMEQALKENRRDRWPLVVLNLDFKTNEPAHHAQVRQVLGRYQRWLTSAPRTATPDQPSPMTVGPLLVLTGSHQSQQTDFHDQLVVGDALWLFGAYEAPPPAGATAEDRALALAATPVETLLAHRATNYRRWANFPWHVIEKGGQPHAGPWDAADRARLDALVSRAHAQGLWIRFYTLNGHPAADADAQGWSKGYNFGNLANAAIRWKAAREAKVDFVATDQYEEYAGERRTQNAGR
>NZ_CP015136.1|WP_110173826.1|6664840_6665416_-|pyridoxamine-5'-phosphate-oxidase
MVDPIARFAEAMARAAQDAPFDPIAMSLATSTSDGRPSCRIVLVHEVNERGVVFHTNYGGRKATEIEANPWAAICAYWPWTDEQVRIEGSIARVSSAESDGYFAVRPRGSQIGAWASLQSQPLESRDALIARVREFEAKFEGGDVPRPDTWGGYRLSPLRIEFWKAGEFRLHDREVYERVGEGWTTHRLYP
>NZ_CP015136.1|WP_110173827.1|6665954_6668594_-|TonB-dependent-receptor
MKTLRTLLAAMFLAAGLTTVASAQERPGSLTITVYDTTGAAIAAANVNLTAPDGRITQQLADEKGTVMFQALLPGKYAVVAEFPGFDPNAAAELQVRAGRNTKQDITLEIAGFVEQVDVEQDTADRAVTDSFSTALSASQIEALADDPDEMQQQLEQLAGPGARIRVNGFEGGQLPPKSQIREIRFRFDPFAAENHNAGFPRVDIITRPGNGPIRNNMTLGFRNNALDARNAFSPVQGEGQTQRYGWSIDGPIVKGRTGFSLNVRSNNENDVQTIVALTPEGQYNSLVNQPADRLNVDFNIEHVLTKTHTLRFSFDRDTNSADNLGIGDFDLESRAYSRDGFDNRVRVSDVGSFKKKYLNEIRVQYSWQESDSISASDETTVRVQDAFTDGGAQISGGRKFWELSVADNLDIPLGKKHSVRTGFEVETGNYIGDELRNFAGTFTFPTMLAYETGRPNNYTIREGNPYVEYGNTEAGLFIQDDYRFRKNLLLSFGGRYETQTLIDDKMNFAPRAGMTWSPFKSNKTTVRAGVGIFYDWYETSLYENTIRQDGLHQYDTIIRNPGYPNPYEGGTVIVTAPSIVQVGNDLEMPTVRRFSLGVEQQLLGWLRMRANYFNQHGWNQFRSRNINDPVVGVRPDSTLGNITYLETTGQADSQGLDLNFNFNYQPRRLFGVLGYTIGERNNYTDGALTLPVNSNDLEAEWGPASDDIRHRIFGFFNTELFWGLRAGINYRALSGRPYNITTGFDTNLDGVINERPEGFGRNAGRLPWQSNTDLRLSWGRGFGPSRNPSGPGGMGGGGPVIMRGGPGGGGPGGGGGMMGGPMGGNDKAVRLEVYLQAFNVFNQVNYTRYGSVVSARSYGDPTAAAPARRLELGMRVGF
>NZ_CP015136.1|WP_157899782.1|6668595_6669624_-|hypothetical-protein
MQQQVFRTVAMAGLMSIVATGAAVAQAPAPAPAQTPAPAAAPAKGDPAKAQAVLAAMTKAMGGDKLTGLKSFTAEGESRRVFGEREMSGGIELAGLLPDAFQVVQVMTRPDGMAGPRISQTIKGTDAFRDMTGMGGGGGFMMRMGPGGPGGGPGGPGGGPGGPGAAGPSGANRQDPSIGIKAELYRTLLGIMPSSPLLSALTFTHVAEAEAPNGVADVIDVSGPDGFRARLFVDQAEHRPLMLSYMMRQPRMRQMTAPPQFKNDDERRAYFEEQRKKFEAEPPPPLVEANVFYTDYRKVDGVMLPHKISRQVEGKVQEEWTIEKYKLNAPIKPDQFQKKASN
>NZ_CP015136.1|WP_110173828.1|6669732_6671046_+|aminoacetone-oxidase-family-FAD-binding-enzyme
MKKDAIVVIGAGAAGLMAAITAARAAPQVRVVAVDGAPRLGAKILIAGGGRCNVTHHVVTERDFHGSTPAAIRRVLRAFDVEAARRFFEAEGVPLKRESTGKLFPVSDRAQDVLQALLGAARRAGVELLHPYKVTAIRPDDVGGFEVDGPKGREAPAAATGTVTGGPAGLGASAVILAPGGRSVPKTGSDGSGYAMVSNLGLPLTPRIFPALVPLRLPDGHLVRALSGLATDVRLIVVSSSGRHLASVTGALLCTHQGVSGPAVLDVSRHWQAAMDDDAQSGVLVNWLPDVVAEDLDRRFQNHGARPIRRALAPPLPDRLADALCALAGVDPDEPGATLTRDARKRLVAVCTAWRLPVVGTRGFEVAEVTAGGVPLSALTAGLEARNRPGLFVCGELCDVDGRIGGFNFQWAWASGTVAGRAAAARVAAGTMEPVSG
>NZ_CP015136.1|WP_110173829.1|6671053_6671989_+|TraB/GumN-family-protein
MIRRGSAGLVLVAVLALVVAARSEPAARTPAAAPLLWQGLLGAHQVSLFGTIHVPDPRVLALSPPVRVAFDRADRVVTEIPLDGAQQAELAAALVLPDGQRLRAIVGEAMFARLEARVRAALTPIAPEMAPLVAGMLDRLKPWAALSQLATLEYLPDLLAGRTPLDVKLYGEAVAAGKKVGGLETVAEQAGTFDAFSPEEQATLLDEALRDFEAPAGPTGKQLVEWYLEGNGDKLAAALSQGSRNDALARKFEAEVLVKRNHRMADRIDDLRRDAPGETLFVAVGALHLVGSDNLPQLLQARGYEISRVRP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015136_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_7

7112905-7112974

Orphan

Consensus_repeat	Method
GCGTCGACCTAAAGGTCGACGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_7

>merge|NZ_CP015136|7|7112905-7112974|CRISPRCasFinder
GCGTCGACCTAAAGGTCGACGTCTACAGCCCATTCATCGCCTCGACCGCGTCGATGTGAAGGTCAAGCGC

>NZ_CP015136|7|7|7112905-7112974|CRISPRCasFinder
GCGTCGACCTAAAGGTCGACGTC	TACAGCCCATTCATCGCCTCGACC
GCGTCGATGTGAAGGTCAAGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_110174163.1\|7107108_7107651_-\|peptide-deformylase	unknown	unknown	gnl\|CDD\|234668
NZ_CP015136.1\|WP_110174175.1\|7122917_7125644_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP015136.1\|WP_110174928.1\|7105322_7105712_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319911
NZ_CP015136.1\|WP_157899854.1\|7104116_7104917_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293836
NZ_CP015136.1\|WP_157899857.1\|7115313_7116927_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|224423
NZ_CP015136.1\|WP_110174166.1\|7113156_7113825_-\|DUF1211-domain-containing-protein	unknown	unknown	gnl\|CDD\|377696
NZ_CP015136.1\|WP_110174168.1\|7114228_7115218_-\|folate-binding-protein-YgfZ	unknown	unknown	gnl\|CDD\|223431
NZ_CP015136.1\|WP_110174167.1\|7113821_7114229_-\|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|239517
NZ_CP015136.1\|WP_110174171.1\|7118305_7119601_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NZ_CP015136.1\|WP_110174162.1\|7106278_7107106_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376804
NZ_CP015136.1\|WP_110174170.1\|7116951_7118298_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NZ_CP015136.1\|WP_157899855.1\|7105793_7106282_-\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP015136.1\|WP_110174172.1\|7119604_7120801_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP015136.1\|WP_110174161.1\|7104933_7105209_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_157899856.1\|7111206_7112097_-\|squalene-synthase-HpnC	unknown	unknown	gnl\|CDD\|274592
NZ_CP015136.1\|WP_110174173.1\|7121336_7122524_+\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|240629
NZ_CP015136.1\|WP_169812048.1\|7110251_7111256_-\|presqualene-diphosphate-synthase-HpnD	unknown	unknown	gnl\|CDD\|163278
NZ_CP015136.1\|WP_110174929.1\|7108914_7110255_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274593
NZ_CP015136.1\|WP_110174174.1\|7122542_7122875_+\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238017
NZ_CP015136.1\|WP_110174164.1\|7107775_7108849_-\|class-I-fructose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|236431

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_110174163.1\|7107108_7107651_-\|peptide-deformylase	gnl\|CDD\|234668	PRK00150, def, peptide deformylase; Reviewed.	2.9088e-63
NZ_CP015136.1\|WP_110174175.1\|7122917_7125644_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.64814e-103
NZ_CP015136.1\|WP_110174928.1\|7105322_7105712_-\|VOC-family-protein	gnl\|CDD\|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	9.6992e-23
NZ_CP015136.1\|WP_157899854.1\|7104116_7104917_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293836	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.56441e-27
NZ_CP015136.1\|WP_157899857.1\|7115313_7116927_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	4.91502e-16
NZ_CP015136.1\|WP_110174166.1\|7113156_7113825_-\|DUF1211-domain-containing-protein	gnl\|CDD\|377696	pfam06736, DUF1211, Protein of unknown function (DUF1211). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. These may possibly be integral membrane proteins.	2.00589e-15
NZ_CP015136.1\|WP_110174168.1\|7114228_7115218_-\|folate-binding-protein-YgfZ	gnl\|CDD\|223431	COG0354, COG0354, Predicted aminomethyltransferase related to GcvT [General function prediction only].	4.47091e-48
NZ_CP015136.1\|WP_110174167.1\|7113821_7114229_-\|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	1.55826e-45
NZ_CP015136.1\|WP_110174171.1\|7118305_7119601_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	2.98974e-38
NZ_CP015136.1\|WP_110174162.1\|7106278_7107106_-\|hypothetical-protein	gnl\|CDD\|376804	pfam02511, Thy1, Thymidylate synthase complementing protein. Thymidylate synthase complementing protein (Thy1) complements the thymidine growth requirement of the organisms in which it is found, but shows no homology to thymidylate synthase. The bacterial members of this family at least are flavin-dependent thymidylate synthases.	1.67097e-06
NZ_CP015136.1\|WP_157899855.1\|7105793_7106282_-\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	1.16194e-38
NZ_CP015136.1\|WP_110174172.1\|7119604_7120801_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	2.41196e-44
NZ_CP015136.1\|WP_110174170.1\|7116951_7118298_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.90348e-49
NZ_CP015136.1\|WP_157899856.1\|7111206_7112097_-\|squalene-synthase-HpnC	gnl\|CDD\|274592	TIGR03464, HpnC, squalene synthase HpnC. This family of genes are members of a superfamily (pfam00494) of phytoene and squalene synthases which catalyze the head-t0-head condensation of polyisoprene pyrophosphates. The genes of this family are often found in the same genetic locus with squalene-hopene cyclase genes, and are never associated with genes for the metabolism of phytoene. In the organisms Zymomonas mobilis and Bradyrhizobium japonicum these genes have been characterized as squalene synthases (farnesyl-pyrophosphate ligases). Often, these genes appear in tandem with the HpnD gene which appears to have resulted from an ancient gene duplication event. Presumably these proteins form a heteromeric complex, but this has not yet been experimentally demonstrated.	5.78647e-87
NZ_CP015136.1\|WP_110174173.1\|7121336_7122524_+\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	gnl\|CDD\|240629	cd05304, Rubrum_tdh, Rubrum transdehydrogenase NAD-binding and catalytic domains. Transhydrogenases found in bacterial and inner mitochondrial membranes link NAD(P)(H)-dependent redox reactions to proton translocation. The energy of the proton electrochemical gradient (delta-p), generated by the respiratory electron transport chain, is consumed by transhydrogenase in NAD(P)+ reduction. Transhydrogenase is likely involved in the regulation of the citric acid cycle. Rubrum transhydrogenase has 3 components, dI, dII, and dIII. dII spans the membrane while dI and dIII protrude on the cytoplasmic/matrix side. DI contains 2 domains in Rossmann-like folds, linked by a long alpha helix, and contains a NAD binding site. Two dI polypeptides (represented in this sub-family) spontaneously form a heterotrimer with dIII in the absence of dII. In the heterotrimer, both dI chains may bind NAD, but only one is well-ordered. dIII also binds a well-ordered NADP, but in a different orientation than a classical Rossmann domain.	0
NZ_CP015136.1\|WP_169812048.1\|7110251_7111256_-\|presqualene-diphosphate-synthase-HpnD	gnl\|CDD\|163278	TIGR03465, HpnD, squalene synthase HpnD. The genes of this family are often found in the same genetic locus with squalene-hopene cyclase genes, and are never associated with genes for the metabolism of phytoene. In the organisms Zymomonas mobilis and Bradyrhizobium japonicum these genes have been characterized as squalene synthases (farnesyl-pyrophosphate ligases). Often, these genes appear in tandem with the HpnC gene which appears to have resulted from an ancient gene duplication event. Presumably these proteins form a heteromeric complex, but this has not yet been experimentally demonstrated.	2.09878e-85
NZ_CP015136.1\|WP_110174929.1\|7108914_7110255_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|274593	TIGR03467, HpnE, squalene-associated FAD-dependent desaturase. The sequences in this family are members of the pfam01593 superfamily of flavin-containing amine oxidases which include the phytoene desaturases. These sequences also include a FAD-dependent oxidoreductase domain, pfam01266. The genes of the family modeled here are generally in the same locus with genes involved in the biosynthesis and elaboration of squalene, the condensation product of the polyisoprenoid farnesyl pyrophosphate. This gene and its association with hopene biosynthesis in Zymomonas mobilis has been noted in the literature where the gene symbol hpnE was assigned. This gene is also found in contexts where the downstream conversion of squalene to hopenes is not evidence. The precise nature of the reaction catalyzed by this enzyme is unknown at this time.	7.52868e-103
NZ_CP015136.1\|WP_110174174.1\|7122542_7122875_+\|FHA-domain-containing-protein	gnl\|CDD\|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	1.64228e-18
NZ_CP015136.1\|WP_110174164.1\|7107775_7108849_-\|class-I-fructose-bisphosphate-aldolase	gnl\|CDD\|236431	PRK09250, PRK09250, class I fructose-bisphosphate aldolase.	0

>NZ_CP015136.1|WP_157899856.1|7111206_7112097_-|squalene-synthase-HpnC
MTLEQAYARCQQVATAHYENFPVASRLLPGQMRPHVAAVYAFARAADDFADEGDIPQARRLEWIEQWRVLRQRPPASMTAATGVGQVPAEDVRATFIAVHDTITRCRIDPQLFDDLLSAFAQDVTTTRYETWDSVLDYCRRSANPVGRLVLGIAGVRDEESARQSDAVCTALQLANFWQDLGDDWRTRNRLYVPSELLHEYGADLHALDGGGVDAAWARVIDELGARTNALFDEGRPVCDAVHGRLRYELRATWLGGTTILRKTLEVRRRSLHERPVLTWADLMRIAIGAIRWRSG
>NZ_CP015136.1|WP_169812048.1|7110251_7111256_-|presqualene-diphosphate-synthase-HpnD
MTSCVSRSGRSGGDQGRARSPNGAPIIATVKAGLGEPALPSPQVARIDPVTVGRDTNFALSFLALSADRREAITAVWDFCRAVDDEVDEHEERPLAERAAGLQRWREEVTACFDGGRPRTPQGDALQRVVRRFPVQRLPFEQLIDGCAMDLEPTRFATFCDLRAYCYKVASTVGLICIEIFGYRNPGTRRYAEELGLALQLTNILRDVPSDLARGRLYLPLDELAAHGVTEGDLRAGRLTPAISALLERQALRAREQFARAEAALPPEDARRLVAARIMGAIYRDLLTRIAAREYDVFAGRVRVPGFHKARLALGTWMRTMASSSASGGLRVAK
>NZ_CP015136.1|WP_110174929.1|7108914_7110255_-|FAD-dependent-oxidoreductase
MTSPDVIVIGAGCAGLAAASALAERGARVLVLEARGQLGGRATAFLDRESGEYVDNGQHVLMGCYHETRRYLARVGAADAVQFQKRLAFTCVDKHGAISRLECPDWRPPLHLAGGLLRWKALSWADRLAATRITGGLKAARRVITHGEPVPVQPGETVAAWLARNGQTPRLIALLWEPLAIAALNQSAAQALAEPFVRVLGQIFSDDRSDAALGVPARPLHQVFGEPARAYLEARGGQIKLDALSRVVVAGDRVGYVDTRGTSVRAANVIVAVPWFGLAGVLRGSEQGALGELVAREATRASSSIVSVNLWLERGTMPSPFVGLPERTFQWMFDKRWAFGETASHFTLVASDADAVLRQSNDELADLALAEARDALPDLRQAKVQRIRVVREPNATFSLAAGEPPRPGTRTAVDGLLLAGDWTATGLPATIEGAVVSGHAAAAAVA
>NZ_CP015136.1|WP_110174164.1|7107775_7108849_-|class-I-fructose-bisphosphate-aldolase
MTATSMPTSEIHALLGAEAEALLTYEAKGFSKDTLHLPGPDYIDRVFAHSDRSPSVLRNYAHILGSGRLAGTGYLSIFPVDQGVEHSAGSSFAINPVYFDPENIVRLAYEGGCNCVTSTLGVLGSVARKWAHKIPFMVKLNHNEFLSYPNRYDQVMFASVEQAFEMGAIAVGATVYFGSEESTRQIQEVSAAFARAHELGMLTVLWCYTRNPAFKTKDVDYHVSADLSGQANHLGVTIGADIIKQKMPENNGGYTALKFGKTHPLVYSDLIPGDHPIEMTRYQLANCYMGRIGLINSGGASTSNDFAESVRTAVVNKRAGGMGLILGRRAFQRPFADGVKLLNALQDVYLDKSITIA
>NZ_CP015136.1|WP_110174163.1|7107108_7107651_-|peptide-deformylase
MSILKVARMGHPVLRSRARALDPSEVRAAVMQKFIDDMMDTMLEYEGIGLAAPQVHEGVRVFVAGIDDGQGKLRVIPFVNPVITPLSETKADDWEGCLSIPDIRGRVPRFTHVRIEALDRKGKPFQLELKDFPARVVQHETDHLDGVLFFDRMAKFDTLTYLDEYSRYHRSAKDDEEEDA
>NZ_CP015136.1|WP_110174162.1|7106278_7107106_-|hypothetical-protein
MPYHAEVLLDSVNPTGQRLITFVLRFPRFVLSEFNTHRMFSRNASSSRAIPTTRLMQQLREDPVLPVEWGRNQSGMQAHEVLDADAARAAEAAWLGARDAALAHAEQLRTTGVHKQIVNRVLEPWMWASVIVSATTYDNFFTLRCHPDAQPEIKRLADLMRAAYEASTPEPRETGEWHLPFVGVDDGDLSIEERKQVSVARCARVSYLTHVGTRDIAADKVLHQRLLDAGHWSPFEHVAVAASGEARFNNFTGWQAYRHQMEQARVLVMSEVAPA
>NZ_CP015136.1|WP_157899855.1|7105793_7106282_-|acyl-CoA-thioesterase
MSSHAFKFATTIRVRWGDCDAFGHVNNASYLSYFEEARIDYWKAVVPDVPFTGMAIVHASVDFRGQAYPGDVLTIRAAVTELRRTSFWAAYEVLRGDAVMATGRSAQVFFDYASQKPALIPDAFRDRIAAYEGIPLTNAERRTPNAEQTTSNDERTTPNANT
>NZ_CP015136.1|WP_110174928.1|7105322_7105712_-|VOC-family-protein
MQPGHVGWVDLTVENATEVRDFYRAVVGWDYREVDMDGGYADFAMTNLEGRDVTGICHARGVNEGLPAQWLVYFIVMDLQFAVDEAVGRGGELLREPTDMGAGQFAVIRDPAGAVCALFQPAEPSATQP
>NZ_CP015136.1|WP_110174161.1|7104933_7105209_-|hypothetical-protein
MRLKLRVDGHPFKNLQTLLEATSSERDGEPSQFQARLVKFFLVVFLLTVPGALSFLLSAEALPEFQQFRISPSPQQATVGGGAEIVKFLQF
>NZ_CP015136.1|WP_157899854.1|7104116_7104917_-|MBL-fold-metallo-hydrolase
MRYTRLTAAHDSAYSRGSVHAYLLHGEVPTLVDAPTSDAAFLDELEAALNAAGDGPLAQVIVTHAHPDHIDGAVAVHARWPATVFRKRAPLPQEDGIDWQVIEKEPMLAAGDSELWVLHTPGHAPDHSCLFDVHGGTLIGGDLAINGSTVAIPADYGGSLREYLQSLRAVLELQPRVILPSHGDPILQPASLLRGYLSHRLAREQQVLECLAAGIDTADAIVDRLYAATADALKPAARQNVIAHLRKLAEDGRVESAGEAWRLRST
>NZ_CP015136.1|WP_110174166.1|7113156_7113825_-|DUF1211-domain-containing-protein
MTVSRDVTRIEAFSDAVFGFALTLLVVSLEVPRTYDDMMGTVRALPAFAASFAILLLIWQEHHNFFRRYGIHDGVTIWMNGLLLFVVLFYVFPLKFLMTMLVGPHGVMFGGRPEAVTGEQMPSLMSMYGIGFVAVFLLLAALHWRARRFLRVESDGSVDLQQLDVHLGACLVYVVIGLSSVALARVPAIWAPAAAGFTYALIGPAHFVYHRFMAPRPGSSAV
>NZ_CP015136.1|WP_110174167.1|7113821_7114229_-|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase
MRDVVVSAAVIERDDAFLLTRRAVDTHLGGRWEFPGGKAEAGETLDATLVREIREELGCGVEVGPLLLTTRHAYPDVHVELHFFSARLVGEPLPQLGQEMRWVARDALEALYLPEADADLVAMLTATDRAPEVHE
>NZ_CP015136.1|WP_110174168.1|7114228_7115218_-|folate-binding-protein-YgfZ
MAVTFDTEYRTVHEDAVWADRSTRDARLEVRGPDATDWLQGLLTQDVKGLQPGQGTYAAYLTPQGRMIADVRVFRRDDTYVLETAASARASLLARLDQFVIMEDVTVTDVTETLGCLTVLGPAAAASASACTGAALATLGALPEHAHLAVGVPGALVAASREFGVPAFDLFAPQESLGIWRTWLQARVPLASERLLETVRIEAGRPRYGVDMHEDTIPLEAGIESRGISFDKGCYVGQEVVIRILHRGGGRVARRLVWVEHTPHAQDGAVWSGGESVHLGDRVVGHVTSACWSPARGGLLAMAMLHRDATEPGALVRIGADEATVRKLP
>NZ_CP015136.1|WP_157899857.1|7115313_7116927_+|alpha/beta-fold-hydrolase
MAQAAPDERWTAAYRIVVQGRNVGSEQVTVVRDASGTTIRSSGGIAGGGYVLRSAEFVYGPSGAPLRMRTEARLKDQTVAIATVVADGKATSKVTQGETASQLTHDVASNAVFLPNNVFAAAQGLAYRVVTMAAGSTVPLYVVPQAQVVATLSAVADERLQTAAGMYEVRRHVLDFDNAGTPMVLMLWAEKATGRLIRYSIAAAGVDVVREDLTSVFTREVKEFRENDQTLLVPAVGFSLGATISRPAGKAAPGKKDKNIEKLPAIVLVGGSGNIDRDTIAHGIPVMGQLAGQLADAGYLVVRYDKRGVGQSGGRAESATLADYADDVLSVVGWLRKQKDVDGRRVYVVGHSEGGAVALIAATRAEDIKAVVTLAAPGTKGTDLVLEQQRQALDGLTIGDDEKQRRVELQKQIMNAVLTGQGWEGVPEATRKQADTAWFRSVLQWDPEPVVRKVDQPLLIMHGALDRQVPVANAELLNGLAAKRKKGPGTLTIVPGINHLLVPAKTGDIAEYGSLSAEKVSPLVATQISDWLKQLPR
>NZ_CP015136.1|WP_110174170.1|7116951_7118298_-|ABC-transporter-permease
MTPPDIAALDSALPVTSAPRVRGGARTIQMCKEVVREAAYGVSRNRLRAGLSMLGISWGIVSVVMLLAYGNGFQDALMVGFRNAFGEGVAVIWPGQTSMQAGGQRAGRRIRLKPEDVALMSELPMVKMASPEYINRLPMTYADKSNTYAIRGVNVAYGAMRGERPGNGQGRWLSDEDVADRRRVVFLGYEVARKLFGAQQAVGQTVRIANRPFEVVGVMEDKVQMSSYFSPDKYCAFIPWTTMGELQDTTYVATLVFQTMNPMQQEKALRQVREVLAKKYRFQAADERAININDSVENMATINGITNGLKVVLTFIGVLTLTIGGVGIMNIMFVSVTERTREIGIRKALGARRREILMQFLVEAFFITFLGGATGVAASWVMVWMFSPRPFLAELLDDMTRQTDIHLVLSLELLGICTAILMVVGIIAGLLPALRASRMDPIEALRYE
>NZ_CP015136.1|WP_110174171.1|7118305_7119601_-|ABC-transporter-permease
MKESFLQALDNLRANKLRSFLTMFGIMWGIVSIVVLSAMGEGFQRGNEAVLREFGRNMSIVWASRTTMQAGGERAGRLLNLTADDARAIKTQGRLVSMVSPEIQRGTKVKSAYNEAAVTVHGVEPPYMFMRTIEVDRGRQLNWSDEENESQVGVIGWEMSKQLFGDREPVGEQVLVNGTPFKIVGRIRRKDQDSNYSGPDNNKLFIPFAVMSKYFPRPDAPAGSLSQLIVMPRQEVVDSLESTLTSRTGRVADIDWPLQREIREILARRKEFNPEDRYAISVWDTSLQTMFFDRMISAMAAFFRVVGLVTLALGGIGVMNIMLIAVRDRTREIGVRKALGATTAAIQRQFFLEGFFLTMISGGLGMLIGVGLCTAVNVYATLPIRFSGMVITWSNALLALGSLVVIGVVSSTLPARKAAQLPPTEALRYEM
>NZ_CP015136.1|WP_110174172.1|7119604_7120801_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MTKMNKRLGMLTLGALVAGGGLYVWSGMNPAKATFEPSRLATVEQDTMVRSVVATGKVEPISKVEIKSKANGIIERLHFDVGDVVKAGDILVELDKENLLAQVREASANVQAADAALLAAKAQLEKNKFEAEGPDVEYAKRAAKRAEDLAAQKLVAQSEFDTAQSAYELAMNRQKVAKGQLVVAQAKVSEAAAQVAQARANLERSEEQLRNATIRAPIAGMVLTRDIEIGSPVSSILNLGANATLVMTLGDIKEVFVRGKVDEADIGQVRYEQHARISVETFKDKKFDGRVTLISPMGAEKDNVTTFEVKVSIDNPGNELKANMTANAEIILEERPNSLIVPEAAISYDAERKASVDLFDPNEPTGRRKVQVKVGISNGTRAQLLEGVKKGDRVILPA
>NZ_CP015136.1|WP_110174173.1|7121336_7122524_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha
MVIGVPRELVPGEDRVALVPASVAPLIKSGAAVLVEQGAGVRAGCPDDAYAAAGATLVSRDQVFAQADILLQVRTAAAAGTYGAADVERLSSRHTVIGFADPLGAPETARAMAARGATVISMELIPRITRAQSMDALSSMANIAGYKAVLLAAATLPRMFPMMMTAAGTISPARVFVIGAGVAGLQAIATAKRLGAKIEAYDVRAAVKEQIESLGAKFVELPLDTAAAEGQGGYAAAQDESFYRRQRETMARVVAHSDVVITTAAIPGKKSPVLITADMVASMPPGSVIVDLAAERGGNCELTVADETIVAHGVTIHGPTNLPATVPFHASQLYAKNLTTLLAHLRTKQGDLVIDPADEITREVLVTHKGEVIAPRLREQLGLAPLPAPVAAAAV
>NZ_CP015136.1|WP_110174174.1|7122542_7122875_+|FHA-domain-containing-protein
MWILRTVQGHEPALTFRLMPGTIKTLGRAVRADFIVDAAMVSRLHCRLTAQPTGQLEIEDLQSTNGTYVNGRRVHKATLLPGDTLRVGRVDLVLVHAPLNQVETTLEAGS
>NZ_CP015136.1|WP_110174175.1|7122917_7125644_-|serine/threonine-protein-kinase
MRLVSAERVGSYEILGHLGSGGMGEVYRARDVRLGRTVALKVASDIAGSADADLRARFEREARAIAALDDPHICSVYDIGERDGMLYLVMPCLEGQTLAARLANRRPLPLEDVLRIGLEVAGALERTHRANITHRDLKPANIMLTSTGAKLLDFGLAKVLAPSKANVVPGVTQIATEAPVTAAGTLIGTVHYMAPEQVEGREADARSDVWTFGAVVYEMATGRRPFDGPSAASVIGAILRDQPPPLSSRQPLAPRLLDHVVARCLAKDPDERWQNIGDVGRELRWIAESRAEAPDEAARSPLVRRSLFRWSSVALALAILAASAAALGWFGRGTPIEPSSRASINIALDLGLDAVAGTDIIGASAVLSPDGTRIVFASVDRGGIQGLATRRLDQLEATPLPGTVGAHAPFFSPDGQWVGFFAAGKLKKLRLAGGEPVTLCDAPAGRGGSWSDDGTIVAALDTRDVLKLVSADGGTPRRVTNLGPGEPGHRWPRFLPGGKAALFTVTSAPANHTSASIGIMDFERNLQQVVLPNAGLSPSYLPTGHLAYVSKGTLYAVPFDLDRREVHGDAFAVMAGVADNAVFGAAQIDVSAGGTMVYRSGTTDALRVLEWLDRTGRTAPMGLEPALYQHPRVSPDGSRIAVEVNQGATSHILVYDWQRGTRVRLAGGSGVNTSPRWSPDGQYIVFQSAGRLFSMRADGGSPAQPLTARQNGLQFPGAFTPDGKRLAFFEVTTGRGSLIQTAGLEVNADRLQLGEPVVYRQTSSNNPNPEFSPDGRWLAYMSTDSGGYDIYVRAFPDTGKQWPVTTGGGSHPVWSRSANELFYRADDQRVMVVPYTATGDTFAAGRPRVWSDRRIQYLGLTATFDLAPDGQRVAAVLSAAALEPAQKHATVVLNFFDEVRRRVTTSTR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015136_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_8

7155210-7155365

Orphan

Consensus_repeat	Method
CTAGGTAGGGACGCCTCTCCGAGGCGTCCATCTCCGCAAAGTGGGCCGTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_8

>merge|NZ_CP015136|8|7155210-7155365|CRISPRCasFinder
CTAGGTAGGGACGCCTCTCCGAGGCGTCCATCTCCGCAAAGTGGGCCGTTCCCGATCCCCGAGTCGATCCCCCATGTCCACGGGCCGCGTTACGTGATCAGCTCTCTAGGTAGGGACGCCTCTCCGAGGCGTCCATCTCCGCAAAGTGGGCCGTTC

>NZ_CP015136|8|8|7155210-7155365|CRISPRCasFinder
CTAGGTAGGGACGCCTCTCCGAGGCGTCCATCTCCGCAAAGTGGGCCGTTC	CCGATCCCCGAGTCGATCCCCCATGTCCACGGGCCGCGTTACGTGATCAGCTCT
CTAGGTAGGGACGCCTCTCCGAGGCGTCCATCTCCGCAAAGTGGGCCGTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_110174205.1\|7166091_7167210_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143494
NZ_CP015136.1\|WP_157899861.1\|7155415_7156342_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238920
NZ_CP015136.1\|WP_157899863.1\|7161261_7162842_+\|DUF1800-domain-containing-protein	unknown	unknown	gnl\|CDD\|378055
NZ_CP015136.1\|WP_162472863.1\|7159865_7161167_-\|metallophosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|379868
NZ_CP015136.1\|WP_110174189.1\|7142517_7144236_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP015136.1\|WP_110174193.1\|7146107_7148360_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|350769
NZ_CP015136.1\|WP_110174206.1\|7167222_7167510_+\|BMC-domain-containing-protein	unknown	unknown	gnl\|CDD\|132885
NZ_CP015136.1\|WP_110174194.1\|7148356_7151584_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|274377
NZ_CP015136.1\|WP_110174200.1\|7156412_7158341_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|237425
NZ_CP015136.1\|WP_110174191.1\|7144757_7145105_+\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|237320
NZ_CP015136.1\|WP_110174197.1\|7152701_7153667_-\|2-dehydropantoate-2-reductase	unknown	unknown	gnl\|CDD\|183829
NZ_CP015136.1\|WP_110174203.1\|7162909_7164145_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|226587
NZ_CP015136.1\|WP_110174933.1\|7165074_7166055_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP015136.1\|WP_110174196.1\|7151875_7152694_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP015136.1\|WP_110174190.1\|7144288_7144588_-\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|259856
NZ_CP015136.1\|WP_110174201.1\|7158363_7159746_-\|peptidase-M14	unknown	unknown	gnl\|CDD\|349458
NZ_CP015136.1\|WP_157899864.1\|7164187_7165021_+\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|224007
NZ_CP015136.1\|WP_110174192.1\|7145307_7145571_+\|Smr/MutS-family-protein	unknown	unknown	gnl\|CDD\|376599
NZ_CP015136.1\|WP_110174195.1\|7151597_7151879_-\|DUF1634-domain-containing-protein	unknown	unknown	gnl\|CDD\|377927
NZ_CP015136.1\|WP_157899860.1\|7141063_7142521_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173853

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_110174205.1\|7166091_7167210_+\|alanine-racemase	gnl\|CDD\|143494	cd06820, PLPDE_III_LS_D-TA_like, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Low Specificity D-Threonine Aldolase-like. This subfamily is composed of uncharacterized bacterial proteins with similarity to low specificity D-threonine aldolase (D-TA), which is a fold type III PLP-dependent enzyme that catalyzes the interconversion between D-threonine/D-allo-threonine and glycine plus acetaldehyde. Both PLP and divalent cations (eg. Mn2+) are required for catalytic activity. Low specificity D-TAs show similarity to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. AR exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on its similarity to AR, it is possible that low specificity D-TAs also form dimers in solution. Experimental data show that the monomeric form of low specificity D-TAs exhibit full catalytic activity.	2.50739e-110
NZ_CP015136.1\|WP_157899861.1\|7155415_7156342_-\|hypothetical-protein	gnl\|CDD\|238920	cd01945, ribokinase_group_B, Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time. .	1.47006e-48
NZ_CP015136.1\|WP_157899863.1\|7161261_7162842_+\|DUF1800-domain-containing-protein	gnl\|CDD\|378055	pfam08811, DUF1800, Protein of unknown function (DUF1800). This is a family of large bacterial proteins of unknown function.	5.42695e-157
NZ_CP015136.1\|WP_162472863.1\|7159865_7161167_-\|metallophosphoesterase-family-protein	gnl\|CDD\|379868	pfam16656, Pur_ac_phosph_N, Purple acid Phosphatase, N-terminal domain. This domain is found at the N-terminus of Purple acid phosphatase proteins.	9.48298e-21
NZ_CP015136.1\|WP_110174189.1\|7142517_7144236_+\|sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.86795e-42
NZ_CP015136.1\|WP_110174193.1\|7146107_7148360_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.47077e-31
NZ_CP015136.1\|WP_110174206.1\|7167222_7167510_+\|BMC-domain-containing-protein	gnl\|CDD\|132885	cd07045, BMC_CcmK_like, Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain. Bacterial micro-compartments are primitive protein-based organelles that sequester specific metabolic pathways in bacterial cells. The prototypical bacterial microcompartment is the carboxysome shell, a bacterial polyhedral organelle which increase the efficiency of CO2 fixation by encapsulating RuBisCO and carbonic anhydrase. They can be divided into two types: alpha-type carboxysomes (alpha-cyanobacteria and proteobacteria) and beta-type carboxysomes (beta-cyanobacteria). Potential functional differences between the two types are not yet fully understood. In addition to these proteins there are several homologous shell proteins including those found in pdu organelles involved in coenzyme B12-dependent degradation of 1,2-propanediol and eut organelles involved in the cobalamin-dependent degradation of ethanolamine. Structure evidence shows that several carboxysome shell proteins and their homologs (Csos1A, CcmK1,2,4, and PduU) exist as hexamers which might further assemble into extended, tightly packed layers hypothesized to represent the flat facets of the polyhedral organelles outer shell. Although it has been suggested that other homologous proteins in this family might also form hexamers and play similar functional roles in the construction of their corresponding organelle outer shells at present no experimental evidence directly supports this view.	2.39327e-34
NZ_CP015136.1\|WP_110174194.1\|7148356_7151584_+\|N-6-DNA-methylase	gnl\|CDD\|274377	TIGR02987, m6_adenine_and_m5_cytosine_DNA_methyltransferase, type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family. Members of this family are the m6-adenine DNA methyltransferase protein, or domain of a fusion protein that also carries m5 cytosine methyltransferase activity, of type II restriction systems of the Alw26I/Eco31I/Esp3I family. A methyltransferase of this family is alway accompanied by a type II restriction endonuclease from the Alw26I/Eco31I/Esp3I family (TIGR02986) and by an adenine-specific modification methyltransferase. Members of this family are unusual in that regions of similarity to homologs outside this family are circularly permuted. [DNA metabolism, Restriction/modification].	3.18581e-19
NZ_CP015136.1\|WP_110174200.1\|7156412_7158341_-\|PAS-domain-S-box-protein	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	4.26041e-96
NZ_CP015136.1\|WP_110174191.1\|7144757_7145105_+\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|237320	PRK13258, PRK13258, 7-cyano-7-deazaguanine reductase; Provisional.	5.81414e-64
NZ_CP015136.1\|WP_110174197.1\|7152701_7153667_-\|2-dehydropantoate-2-reductase	gnl\|CDD\|183829	PRK12921, PRK12921, oxidoreductase.	1.08891e-74
NZ_CP015136.1\|WP_110174203.1\|7162909_7164145_+\|DUF1501-domain-containing-protein	gnl\|CDD\|226587	COG4102, COG4102, Uncharacterized protein conserved in bacteria [Function unknown].	2.98417e-78
NZ_CP015136.1\|WP_110174933.1\|7165074_7166055_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	5.52808e-54
NZ_CP015136.1\|WP_110174196.1\|7151875_7152694_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	7.81251e-26
NZ_CP015136.1\|WP_110174190.1\|7144288_7144588_-\|HU-family-DNA-binding-protein	gnl\|CDD\|259856	cd13834, HU_like, DNA-binding proteins similar to HU domains. This subfamily consists of DNA-binding proteins similar to HU domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta).	4.52697e-20
NZ_CP015136.1\|WP_110174201.1\|7158363_7159746_-\|peptidase-M14	gnl\|CDD\|349458	cd06239, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavage. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	6.35239e-83
NZ_CP015136.1\|WP_157899864.1\|7164187_7165021_+\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	1.24319e-24
NZ_CP015136.1\|WP_110174192.1\|7145307_7145571_+\|Smr/MutS-family-protein	gnl\|CDD\|376599	pfam01713, Smr, Smr domain. This family includes the Smr (Small MutS Related) proteins, and the C-terminal region of the MutS2 protein. It has been suggested that this domain interacts with the MutS1 protein in the case of Smr proteins and with the N-terminal MutS related region of MutS2. This domain exhibits nicking endonuclease activity that might have a role in mismatch repair or genetic recombination. It shows no significant double strand cleavage or exonuclease activity. The full-length human NEDD4-binding protein 2 also has the polynucleotide kinase activity.	4.23051e-18
NZ_CP015136.1\|WP_110174195.1\|7151597_7151879_-\|DUF1634-domain-containing-protein	gnl\|CDD\|377927	pfam07843, DUF1634, Protein of unknown function (DUF1634). This family contains many hypothetical bacterial and archaeal proteins. A few members of this family are annotated as being putative transmembrane proteins, and the region in question in fact contains many hydrophobic residues.	6.24872e-09
NZ_CP015136.1\|WP_157899860.1\|7141063_7142521_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.28387e-57

>NZ_CP015136.1|WP_110174197.1|7152701_7153667_-|2-dehydropantoate-2-reductase
MSDATFAVVGAGAVGGYYAARLAHAGFDVALLARGAHLEAIRSRGLWVWSPLGDLVVHPRVSADAAGIGPADVVLYAVKTYDNATALPLLGPLLGPDTLVVTLQNGVSSAADVGTVVGVDRVLAGPTYIATALKAPGLIQQTGTHRRIVFGEIPDTVGPALRARPSAEPSPRVLALAELLRRADIQAEPVADARVPLWEKFVYLAPFAAVTGAARQPAGVVWSTPALRATLDAAFAETEAVARAEGIAVAPDVLDRVRGYMDALPAGTRSSLLIDLQAGKRIELDALAGDVVRRGAALGVPTPVMATLASTLTPYIGGSSR
>NZ_CP015136.1|WP_110174196.1|7151875_7152694_-|sulfite-exporter-TauE/SafE-family-protein
MTLLGIVGVMALGALGGMVGALLGLGGGVFLVPALTLVYGLPFRQAAGIGLMTVIATSSVVSAQKLGDGTVNFRLGIVLEIATTIGGLAGGLTAQALPQRTLRLLFGAVALFIAGVMFREIYRRTTDQESTDGTGWLGGQWYCDEQKRLRAYRVRRLPLALFVSFLAGNVSGLLGIGGGILKVPALTTWCGVPLRVSATTSAMMIGVTAAASAPLYYAAGEIPPMYAAASVLGVMVGTRGGFWIAERAKARGLKVLLGLVLVFVAVMMLVRA
>NZ_CP015136.1|WP_110174195.1|7151597_7151879_-|DUF1634-domain-containing-protein
MTTFETVLARTLRTGVMVSTGLLAAGLCLALARPGPAADLLLQTGLIVLMGTPMARVLISCAEYVRERDWFFAVNAFGVLVVLAVTIWHAWRG
>NZ_CP015136.1|WP_110174194.1|7148356_7151584_+|N-6-DNA-methylase
MSAAWVTGGRVWSRVVERHLATALLHGASEEAAARAMRRCICTWRGASETLGPASGAAAVWEHLVRPCAEALGWSPRRDAAVPVGGIHMRVGEAALGPVRQLLVAMPWGMAHEGLQRAATRLGAARDTRWVAACNGQSWRWYDATRPYAREHMAIDLAHASIDARVWQVLWLLGQLVRSTRSARTPDMPWLERLVTSSASEGAGAAAALRDGVSSALAGLARRADGDHDAHVMLVFQWLFLLFAESRSLLPMWHPAYRRSYAVSSLARESAPTRVSAVGVHEGLAAIGRLGRDGAELGGLTVRALGGPLFSGTLKARRSGRIADAELGTMLAQLTHGSGPRSGTPIDFGELGVEHLGSLYERLMSPPVADGSPALLRKRTGAFYTPRVLADMLVERTLDPLVRGASSREILGLRILDPAMGSGALLASALRYLVAAVEAAWIREGLGGPLDVPRHERESLPRCIAEQCLYGVDVNARAVDVARLSIWLLSMAPDRPLTWLDAHLRVGNSLVGTSPSTILSRLPGRDRWPRRRADAQLTLFDLEQWHHEAAEIGPMMEALVARPTESAAAAGDKSRALASLRSRKVLAAWRARADAWCGAAMEVDPPTSGLWRAVDEALRVGGASPGAGAAQVYQFTDCWLASADAQHCLHWSLEFPEMFENGRHGFDAVIANPPWEMLRGDLGSGADRTAARNDLAPLLRFVRRSGLYREVGGHVNSYQLFLERMLQLVRPAGRLGCLLPGGMLVDHGAAALRRLVLDRVSVDQLSIFDNRDAIFPIHRSVRIVAMTGTSGGPTEAMLVDDGVLATTAVRTQRATEAPRLLPRTLLRQASGDLEAVPWVRDGDQVRLLGQLLSFPRLGGAHWHLRFGRELNATEDRALLRSGPIPDGGLAVVDGKHLQAFSVCPPDTASWVSVVDAARALPDQRWRQWRLAYRDVSSATNMRSLIAALLPPACVSTHTLFCLRTRLGLPTQLYLCGMLNSLVADWFVRRYLGGHVTTSLIASLPVPKVAATHPLRRRVVRLTARLMRTADDERAQGELQAAAATLYALGQESRATVAADFPRLSPVVRERLLGGE
>NZ_CP015136.1|WP_110174193.1|7146107_7148360_+|DEAD/DEAH-box-helicase
MLHTEVRPSDAAAPADGTSARVWCRARTWRVLDKRSAGGTTLWRLVRKAEVPRLIASPPDEVSAMRMGRRAVSRQTWIRDAVAHVRSHAPVWWPATATTLPVAALAWQLVPAMMVLSGHHRRVLLADAVGMGKTIQAGVLLHEIHAREPDATTLVITPATLVAQWATELRTRACLTPAVLDAAALRREAEYPRAMVDAARAGTCWLMSIDLLRQPDVVALLVRTRWTLLVVDEAHAAAPGTARLEAVSRVAGASVRMLLLTATPSAGGAADGLRRLGARAGEAPMPVVRRDASLLSRPHRRSLALRAGLDADHAALCARLDRFVERARVESGARGLLPALVLRRRASSCPAALRRSLERRLEVLGESATTGTPSVLPSLFEPDPFTSQDERDDEVMRVVAWSDATAERTELERLLELARQVPPAGRKLGCVRRLVRRCREPVVVFTAFLDTLRALRALLPAEGVVMVHGEQPDALRAHAIRSFTVGDAAVLLATDTAAEGLNLHARCRLVVHAEVPSSSRIFEQRTGRLDRYGQSRRVHAVIISSLTREDREAMERLQARTQRDKQWIAGAGATTCRRTAVAARRLALDVAQERPAAGAAPERDRDVPAIRACALPPRRWRRLVSRLELPIGTTAVWTATWRIAGGPELSASRVPVLVAGDSSGPPDLTSAARQGAMRGRVTRAVWLVRRLTRWEADAARAIEMDESMNAMPDLFADAPHGHEIRPTRRQPDLWATLEGETMIGPAAGVR
>NZ_CP015136.1|WP_110174192.1|7145307_7145571_+|Smr/MutS-family-protein
MEDPHVVPIGPEFDLHPFAPRDIPDVVDAYLEAAHAAGLREVRLVHGRGIGVQRARVHQVLSAHSLVASFHDDPRSHLGATIVTLIE
>NZ_CP015136.1|WP_110174191.1|7144757_7145105_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MASAGIETFPNPRPGRPYEIETRCPEFTSMCPVTGLPDFGEIRITYVPDATCIELKSLKYYLLDFRNKGVFYEALTNQILDDLVASCAPLRMTVVGDFTPRGGIRTTVTATYQKD
>NZ_CP015136.1|WP_110174190.1|7144288_7144588_-|HU-family-DNA-binding-protein
MAQAQKMTKSALFAFFADKFEVKRTEVRDWFDELAALAEKEIKRSGEFTLPGMVKLSVRKSKARMGRNPATGEPIKIPAKTRVKATVVKAMKDAVMPRK
>NZ_CP015136.1|WP_110174189.1|7142517_7144236_+|sensor-histidine-kinase
MIPITRRMALLVTTAALVPLLIFGLVAGWTLRTTTQNSVRENHAAIAARAAETIALYLKSTEKLVKSAVSDLEGTGLTHAQQQRVLLNQVTNTPEIKVLTLYDARGVPLATSDLTPAPPAPLAHLTEAALTVLPVDLDGDQWPRTRLTLRLDEPLAPYLVAELQLEELWQVVDNVKVGMSGRAFLVDDTGRIIADGRPDGKKRIARRERIGAHPLARATTVAGASYTRAYDGVEVLAVATAPLERYGWRVIVEQPTADAFAPATRLEQQLLRFVTLALLANIAIGIAFGRSLLRPISDLLGGIRAIGEGRLDQRVHITRDDEFRLLGDAFNATADKLGELQQAAIRQERQAMFGRIAAGLVHDLSHPIQNINNNCKLVLQMHDDAEYRATFAKLVKREFSTIQRTFEDLRNLARPIPLEKFPVDAGKLMVDVVERMQAQASVAGVTVAASEVPERTLYLEGDLFALGRVLRNLVLNALQATPPGGRVWIEVDGNDDRVQVHVCDTGCGIPADRIQAVFEDFVTTKRRGLGLGLAISRKIVEQLGGSINVTSTVGEGSRFTLAFPRLSRIAGM
>NZ_CP015136.1|WP_157899860.1|7141063_7142521_+|ABC-transporter-substrate-binding-protein
MLLVFACLPGIVIATAGCGRADAPAAAVPARITVALPSADVPIAPLLFLLTQTRLVSVDQTGIEQPALIERWTRSDDQRTWTLFVRDGVRLHDGRIVTAADVVTRVREAVDRPSTPGLWPVTSVEEAGPREVRVHLREPTSLLLESLSVTQAVDAGAYQAKDDAPAEPELVAVPQSGHGPPSIGTIQVRRYETPRAAVAALLREDVDVLYEVPSEARGLLAVEDGVQIFPNVKPYVITLGFNHRHPILRRRDVRLAMNIAVDRQALVAQVAGGVGIPAADMLWHQHWTHPHVDDAQAFPVDRQRAGQLLDASGLQQRRTPTGAIEPRFRVTCLVVDDPMMQRIARRLQKAYADIGISIDLEPIALEALGTRLASGHFDAFVSPVVSGYGMSMPYASFGNHGHPRMIDHGYTAAAPAAELVRAAATREAFVEAVHALHRTLIEDPPAVSLFWSETSRAVGRRVTVPDSSGDVLGSLARWTVRSKGQ
>NZ_CP015136.1|WP_157899861.1|7155415_7156342_-|hypothetical-protein
MPTPDVLWDVVGLGANAVDFVYRLPAVPQATGNFSKMRISRETISCGGQMTTALVACARFGLRAKYIGATGTDDNGRRIRRELAHHSVDCTDAIIKDARNQYAVIMVDEVTGERIVLWDRDEKLHLRPHEIPARAIVSARLLHVDDVDQEAAIVAGEIAKTAGLVVTSDIDRLTPRTVDLVRAVTVPIFAEHVPTGLTGTKDLASALRQLREMHPGLLCATIGAEGAIALDGDRLVHSPGFKVQAVDTTGAGDVFRAGFIYGTLQGWSTDQVLRFANAAAGLSCTRPGAIGGVPALEEIEALLEAAPA
>NZ_CP015136.1|WP_110174200.1|7156412_7158341_-|PAS-domain-S-box-protein
MSKPQVTTPMAALAATADQTARREQATVSAWGELMQAARVTAAEQDLDLRYVAVLDQPGMPDVSHVIGQLETEVYSGDVAERLVAIKRAAIERGRPHQGRVELEHDGRSCSFEVTATPRRNERGEVVGVLSMAVDLSDALRAHEQHRTSQGRLAGILDSAMDAIVSTGPDHRVLFFNPAAERMFGVPAAQAIGSDVTRFVPPAAGDEHSALIRHLDGLTTGDRRITVSDLCAVRASGEAFPIEASIAHTGAADDQLFTIIIRDRTERDQLQAHLLQSQKLEGIGRLAGGVAHDFNNLLTVILGYCELLRMRQRGGTELEEINNAARRASQLTRQLLAFSRRQVLHVETLDLNTLIRGLHRMLRRIVGEDVGLTTHLAEEQLWVVADFGQLEQVLLNLVGNARDAMPAGGSLRIATRIIDRPVHAESSGRPSVELMIQDNGVGMAEEVRSRIFEPFFTTKGDAGTGLGLATVYGIVTQTGGEIECDSAPGAGTTFRVFLPLAQAQREPSAGASVSRHPAHGHETVLLVEDEPIVRELAARALRQYGYKVLEAQDAESALRFMDLPNLGIVVSDVVMPGRTGDDLSAEFARRRPGLPVLLMTGYSEAMLQRPVDPAHLLRKPFTPTELIAKIRALLDRSPTAGA
>NZ_CP015136.1|WP_110174201.1|7158363_7159746_-|peptidase-M14
MLRLELPGAASLRAGVLLACACVAPACTVASQELQPLTPDALARTWEAERLPLPAPPLVTHAIVEARVARLVRESGGLVTSEVLGTSVEGRAIHHLTIGRGAKPVLLWSQMHGDEPTATSALFDLCQWLVRHRQEPIVARLLDSLTLHIVPMLNPDGAERFQRRNAQFIDINRDALHLQTPEGRLLKGLRDRVEPVIGFNLHNQNWRTSVGTPPQPAAVSLLAVAYDEARSEDPRRQLTKRTCSVIVEALRPLASGRIGRYDDEFEVRAFGDNITKWGTGVVLIETGPWPGPEPDRTLVQLNFVALVTALDAIASARVSNVDPSLYERLPENQSDLFHTLVMGGTVIPGTGVTPFRADVGIVGTRVVRQGPGGRVLQWQGSIQDVGDLRVYGALETVDASGLFVSPAYTAAAVGDEVSLPPGNATASTPRVVPGGPARLWLLRGGSVPDRYRLERIVDLP
>NZ_CP015136.1|WP_162472863.1|7159865_7161167_-|metallophosphoesterase-family-protein
MPVRRLLHGVLLCVLTLGAWSMVAPAQAPIPVHSADPGRRPSRVVLTWRDDPARTQAVTWRTDALVEETFAEIVEASANPGSTALARRSPARTTAVPVPAGTAYYHEARFTALRPGTTYMYRVGDGGTWSEWFQFRTATVEPAAFSFIYLGDAEADVASLWSRAIRAAFADAPRARFVLHAGDLVNVGESDDQWGEWFGAGAWINGTVAQVPVVGNHEYGRVNREDPPQLTALWRPQFSLPEDGPEGLSETTYSFDYQGARVIVLNSAEDGRLADQAAWLESRLKDNKNRWTIVAFHHPVFSVAGDGDNAALRAAWKPLFDKYEVDLVLTGHDHTYGRGENLTEGGPRRDDAGTVYVVSVSGPKMFEVGKNRSWATRTGANLQLYQVVHVAPQSLRFEARTVSGQLFDAFEITKSRNGRRRFIDRKPELSGTY
>NZ_CP015136.1|WP_157899863.1|7161261_7162842_+|DUF1800-domain-containing-protein
MRASFSRSLAWVGVVVAATAMTVSGTGRPPALDRDAAIHTANRLTFGATPATVERLQSEGLDAWLEAQLHPQRVPDPRLEARLAALTTLTLTPRALAEMNLKAQQRRRAAQASMQTAGAGDGGLERAAGGIEPGMERFPRAEDRGPQRQVLIELITQKLVRATAAERQLEEVLVDFWFNHFNVFAGKGPVRQYVYDFERTAIRPHVFGSFRTMLGAVAGSPAMLFYLDNWQSSAPGTQTLRGPGGLNENYARELLELHTLGVDGGYSQADIVDVARAFTGWTIRAPRQGGDAIFDGRRHDRGAKTILGHVLPAGGGRGDGERVMDILARHPSTARFIARKLAIRFVSDTPQEALVARVASRFLQTGGDLRATVDALVRSPEFIDRSARLAKVKTPLEFVASAVRVTGAEVRMAGALGQQLRTLGMPPYFAQPPTGYSDRADAWTNAGALVQRMNIALALTQGRLHGVAPAGLPEADGDDAETRARSMARALLLRDPSPATLKTVAMASIPAEMAALVLGSPEFQRK
>NZ_CP015136.1|WP_110174203.1|7162909_7164145_+|DUF1501-domain-containing-protein
MRENRRVFVKQGAVALLSLGFAPHFLARAVAATTRRRKVVVVVFQRGAVDGLNMVVPHGDGEYYAARPTIAIARPGSTGGALDLDGHFGLHPRLEPLHGLYSRGQFAVVHACGSPDPTRSHFDAQDYMETGTPGVKSTQDGWLNRVMAQRHDAEHAGAMRAVALSPQLPRMLQGHAPALAMSSIERMGVAGGARTGDAFEAQYAAAADQVLRQTGQEAFDAMRTLRAVEARGPRTAAGAAYPRTPFGNALRQVAQLVKADVGLEVAYAEIGGWDTHVNQGGADGQLALRLSDVGRSLGALVTDLGTQMQDVVVVTMSEFGRTIAENGTRGTDHGHGNAMLVLGGPVRGGRVFGRWPGLTREQRVDGRDLAITTDFRDVFSEVLALHLGVDDLRPVFPGHAWQPSRRLGLLA
>NZ_CP015136.1|WP_157899864.1|7164187_7165021_+|sugar-phosphate-isomerase/epimerase
MNAPSLSARLAVCSWSLQPASPQELIAAVRATGLNRVQLDLDPLRESPDVWASTQALLEEAGIEVVSGMFRTVGEDYTTMETIRVTGGVAPDATWEPNKANIAATVPIAKQLGMRLVTFHAGFLPHDETDPAFVTLAQRLRDIADMFAAHGIGVGLETGQETAPALRDLLKILDRPTLSVNFDPANMVLYDKGDPIDALRTLGPWIGQVHIKDGIRTKVPGEWGEEVVVGSGDVDWTAFFAALHEVGFTGDLCVEREAGTTRVADIAAARELVEAIQ
>NZ_CP015136.1|WP_110174933.1|7165074_7166055_+|Gfo/Idh/MocA-family-oxidoreductase
MGLTHINAYRKIAGVDVVAVCDAVRQPVNGVLTGIAGNVAGSDTVDLGASVCAYSKIEDLLADDAVDLVDLCLPTPLHVPQTLAALQAGKHVICEKPLARTSAQSRLIVDAAATAKTFFMPAMCMRFWPGWAWLKDLKAAGTHGDILTARFRRVSAPPGWSRDTYFKGGDSGGALFDLHVHDTDFVQYLFGRPTAVFSTGVSRFSGATDHVVTQYMVPGGATVYSEGSWLLASGFAMSYTVMFERATIDYDSARGNAALQVWEEGKEPQVIVPEGPDGYVGELQHLITAIRTGQAPSIVTAQDGLSAVEICEAEERSVQTGQVVTL
>NZ_CP015136.1|WP_110174205.1|7166091_7167210_+|alanine-racemase
MANLTELQTPLVVVDAPAMRRNITRMAEAAAAGGKLLRPHGKTHKSGWIAREQIAAGAVGMTCAKPGEAEVFAAAEIQDIRIAYPISPTYAPRILSLMDGVRISTIVDDLEVAGGWSDAMVAAGRRLEVLVKIDVGTHRCGVDPRQRDALGFIERVSGMPGLDLRGLLSHAGHSYAAGSVEEIADVARAEAAMMAELVEGCRARGVALEEVSVGSTPTALVSATLDGITELRPGNYVFHDRTQVGLGVVDWPGCALRVHASVTTFPAPDRLVLDCGSKVLSSDGARGFSATPGFGVILGPDGQPDPGLLIERLSEEHAVVRVTGPTRLRIGDRVTVVPNHSCVVANLTNLYVVAEGDTVLETCKVDARGLVN
>NZ_CP015136.1|WP_110174206.1|7167222_7167510_+|BMC-domain-containing-protein
MAPRDVGEALGMIETRGLVGMVEATDAMLKTANVTFVSWQKVDAGLVTSIVRGDVAAVKAATDAGAAAARRVGELVGVHVIPRPADEVETIFPIS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP015136_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015136_9

7357828-7357907

Orphan

Consensus_repeat	Method
ATTTTGAATTCTAAATTCTGAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015136_9

>merge|NZ_CP015136|9|7357828-7357907|CRISPRCasFinder
ATTTTGAATTCTAAATTCTGAATTCCCGAGTCCGTATCGTGGCGGTGCTCGGACCCGCGCTCAATTCTGAATTCTAAATT

>NZ_CP015136|9|9|7357828-7357907|CRISPRCasFinder
ATTTTGAATTCTAAATTCTGAATT	CCCGAGTCCGTATCGTGGCGGTGCTCGGACCC
GCGCTCAATTCTGAATTCTAAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015136.1\|WP_110174356.1\|7366368_7366686_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110174341.1\|7349073_7350054_+\|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl\|CDD\|224238
NZ_CP015136.1\|WP_110174352.1\|7358858_7360253_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224157
NZ_CP015136.1\|WP_110174343.1\|7350539_7351130_-\|CHRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377837
NZ_CP015136.1\|WP_110174359.1\|7367322_7368882_-\|deoxyribodipyrimidine-photolyase	unknown	unknown	gnl\|CDD\|129679
NZ_CP015136.1\|WP_110174347.1\|7354189_7354930_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235500
NZ_CP015136.1\|WP_157899895.1\|7356245_7356614_-\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|274132
NZ_CP015136.1\|WP_110174353.1\|7360249_7362214_+\|peptidase-M49	unknown	unknown	gnl\|CDD\|367566
NZ_CP015136.1\|WP_110174360.1\|7369500_7369758_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110174357.1\|7366767_7367004_-\|DUF4926-domain-containing-protein	unknown	unknown	gnl\|CDD\|379816
NZ_CP015136.1\|WP_110174348.1\|7355080_7356025_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381321
NZ_CP015136.1\|WP_110174358.1\|7367000_7367342_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110174344.1\|7351413_7351950_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP015136.1\|WP_162472871.1\|7362353_7364585_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|365914
NZ_CP015136.1\|WP_157899896.1\|7356829_7357678_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238299
NZ_CP015136.1\|WP_110174346.1\|7353125_7353800_+\|DUF1326-domain-containing-protein	unknown	unknown	gnl\|CDD\|369182
NZ_CP015136.1\|WP_157899899.1\|7364560_7365862_+\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|377697
NZ_CP015136.1\|WP_157899897.1\|7357917_7358709_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373032
NZ_CP015136.1\|WP_157899894.1\|7350064_7350301_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015136.1\|WP_110174345.1\|7351946_7352927_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|183067

Protein	Function_ID	Function_description	E-value
NZ_CP015136.1\|WP_110174341.1\|7349073_7350054_+\|xanthine-dehydrogenase-family-protein-subunit-M	gnl\|CDD\|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	4.26111e-66
NZ_CP015136.1\|WP_110174352.1\|7358858_7360253_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224157	COG1236, YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis].	4.4498e-104
NZ_CP015136.1\|WP_110174343.1\|7350539_7351130_-\|CHRD-domain-containing-protein	gnl\|CDD\|377837	pfam07452, CHRD, CHRD domain. CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..	4.33356e-10
NZ_CP015136.1\|WP_110174359.1\|7367322_7368882_-\|deoxyribodipyrimidine-photolyase	gnl\|CDD\|129679	TIGR00591, Deoxyribodipyrimidine_photo-lyase, photolyase PhrII. All proteins in this family for which functions are known are DNA-photolyases used for the direct repair of UV irradiation induced DNA damage. Some repair 6-4 photoproducts while others repair cyclobutane pyrimidine dimers. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	8.03537e-90
NZ_CP015136.1\|WP_110174347.1\|7354189_7354930_+\|SDR-family-oxidoreductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	1.18372e-51
NZ_CP015136.1\|WP_157899895.1\|7356245_7356614_-\|four-helix-bundle-protein	gnl\|CDD\|274132	TIGR02436, S23_ribosomal_protein, four helix bundle protein. This family describes a protein of unknown function whose structure is a bundle of four long alpha helices. Some of the first members of this family were found encoded in the (atypically large) intervening sequence (IVS) of Leptospira 23S RNA, a region often present in the rRNA gene and removed during rRNA processing without re-ligation. However, this location is not conserved, and naming this protein as a 23S RNA protein is both confusing and inaccurate.	8.61398e-18
NZ_CP015136.1\|WP_110174353.1\|7360249_7362214_+\|peptidase-M49	gnl\|CDD\|367566	pfam03571, Peptidase_M49, Peptidase family M49.	7.02921e-28
NZ_CP015136.1\|WP_110174357.1\|7366767_7367004_-\|DUF4926-domain-containing-protein	gnl\|CDD\|379816	pfam16277, DUF4926, Domain of unknown function (DUF4926). This family consists of uncharacterized proteins around 70 residues in length and is mainly found in various Caulobacter, Microcystis and Cyanothece species. The function of this family is unknown.	3.11041e-16
NZ_CP015136.1\|WP_110174348.1\|7355080_7356025_-\|aldo/keto-reductase	gnl\|CDD\|381321	cd19095, AKR_PA4992-like, Pseudomona aeruginosa PA4992 and similar proteins. Pseudomona aeruginosa PA4992 is the prototype of this family. It is a putative aldo-keto reductase that catalyzes the reversible reduction of ketones to the respective alcohols using NAD(P)H as a hydride donor.	1.04069e-58
NZ_CP015136.1\|WP_110174344.1\|7351413_7351950_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	8.48786e-43
NZ_CP015136.1\|WP_162472871.1\|7362353_7364585_+\|peptidylprolyl-isomerase	gnl\|CDD\|365914	pfam00160, Pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD. The peptidyl-prolyl cis-trans isomerases, also known as cyclophilins, share this domain of about 109 amino acids. Cyclophilins have been found in all organisms studied so far and catalyze peptidyl-prolyl isomerisation during which the peptide bond preceding proline (the peptidyl-prolyl bond) is stabilized in the cis conformation. Mammalian cyclophilin A (CypA) is a major cellular target for the immunosuppressive drug cyclosporin A (CsA). Other roles for cyclophilins may include chaperone and cell signalling function.	6.80574e-29
NZ_CP015136.1\|WP_157899896.1\|7356829_7357678_-\|hypothetical-protein	gnl\|CDD\|238299	cd00537, MTHFR, Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase to convert homocysteine to methionine. The enzymatic mechanism is a ping-pong bi-bi mechanism, in which NAD(P)+ release precedes the binding of methylenetetrahydrofolate and the acceptor is free FAD. The family includes the 5,10-methylenetetrahydrofolate reductase EC:1.7.99.5 from prokaryotes and methylenetetrahydrofolate reductase EC: 1.5.1.20 from eukaryotes. The bacterial enzyme is a homotetramer and NADH is the preferred reductant while the eukaryotic enzyme is a homodimer and NADPH is the preferred reductant. In humans, there are several clinically significant mutations in MTHFR that result in hyperhomocysteinemia, which is a risk factor for the development of cardiovascular disease.	0.000142255
NZ_CP015136.1\|WP_110174346.1\|7353125_7353800_+\|DUF1326-domain-containing-protein	gnl\|CDD\|369182	pfam07040, DUF1326, Protein of unknown function (DUF1326). This family consists of several hypothetical bacterial proteins which seem to be found exclusively in Rhizobium and Ralstonia species. Members of this family are typically around 210 residues in length and contain 5 highly conserved cysteine residues at their N-terminus. The function of this family is unknown.	2.82242e-14
NZ_CP015136.1\|WP_157899899.1\|7364560_7365862_+\|threonine/serine-exporter-family-protein	gnl\|CDD\|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	7.54067e-51
NZ_CP015136.1\|WP_157899897.1\|7357917_7358709_-\|hypothetical-protein	gnl\|CDD\|373032	pfam14371, DUF4412, Domain of unknown function (DUF4412). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is typically between 75 and 104 amino acids in length.	0.000311691
NZ_CP015136.1\|WP_110174345.1\|7351946_7352927_+\|EamA-family-transporter	gnl\|CDD\|183067	PRK11272, PRK11272, putative DMT superfamily transporter inner membrane protein; Provisional.	1.70001e-54

>NZ_CP015136.1|WP_157899896.1|7356829_7357678_-|hypothetical-protein
MASFLEALTGPSSVYAVELRPPRAELSSAAGMDAWIDTYHAVRRLVRRGHHVCLTDSAVGAQEEDNLRHLVLNLGDDVPRDHVVPFLTSKHTLQYCLTYADRAQLHGFPALVVLGGDKAVGTPRSVEHAWQLRAAIRARQPTLALGGWANPHRHPERQVEFLQAGDFTGEYYLTQVASHHQVRDVERFLGEASRRGLTMPGMFGVFYYRSARRRTLDMLAEFMPVPIDELVTEFGAGASPETVCARTIRTLKAAGVRHFYISNLPLTDTDAVLHRILDEAGA
>NZ_CP015136.1|WP_157899895.1|7356245_7356614_-|four-helix-bundle-protein
MAREIQERGYRFGRDVMRYAVGCEPSSVIGRDLLRQLFRAATSVGANLQEAHAGVTRHDFVHKIGLARKEAFEARHWLRLRRDMCPSDEALHPLQREADELCRILTAIILSAKRNDSRPAPQ
>NZ_CP015136.1|WP_110174348.1|7355080_7356025_-|aldo/keto-reductase
MLSRREWLNLTLGAGAALTFDRSVLHAQQPLITRAIPSSGEKIPVVGLGSSATFSQVARSEDVTGLREVLKAFTDQAGTVFDTAPSYGASEEVAGRIAGELGVTEKVFWATKVNVAGRGGGSADPAAAKAQIDASFAKLKKGKIDLIQVHNLGDVPTQLGLLKELKKAGRVRYIGVTSTNKSQYAELQTVMRNEPLDFIGVDYAIDNRDVEEAILPLAQQRKIGVLVYVPFGRTRLFTRVGDRQVPDWAKAFGAETWAQFFLKYLIAHPAVTCVTPATSRAKNVVDNLAGGRGQLPDDATRKKMAQYIEGLPSA
>NZ_CP015136.1|WP_110174347.1|7354189_7354930_+|SDR-family-oxidoreductase
MTLSDKVVLITGGTRMGASLAHACAARGADVALSYAHSAHAIDEVVTSVAATGRRAAAFATDLRVAAACASLVDDVIAWAGQLDVLVCLASVYARVPLDELTPQDWQEQLAVDLDASFHCARAAAAHMRPRGAGHVVLCSDWVAASGRPRYTGYLPYYVAKAGVVALTESLALELAADGVQVNAIAPGPILPAAGTTPEMQAAVMQATPLRHWGGPDVVTHAIMGLLDQEWVTGQVVRVDGGRHLL
>NZ_CP015136.1|WP_110174346.1|7353125_7353800_+|DUF1326-domain-containing-protein
MFRAVLALATILAAAPALAADSTSTPATSVTGTYVEARTAEVFAGGCVMNSEAETMGRQALLAWRVDHGNVAGVTIDGLSVVAALSGTHNLGMREMGGEAPTLVKALMYVDERATPAQRDALVSMARTAIGDLAIRVVDVQAVPIAFERTHHAAAVQAGDARLEVEAHIHHDPSCGAMQWFHPLSRGAQAEVGMTRNQTFTGQALGTRWQQIDKRSAFVGTFAF
>NZ_CP015136.1|WP_110174345.1|7351946_7352927_+|EamA-family-transporter
MSRITTRQKAYAAFMAVCFFWGTTYIGIKIALETVPPFLLGGIRFTIAGSVLAVSLRLLGHRWPDWRRAPTFLVIGVAMLGFGNGGVVWAEQFMASGLVAVLVASTPFWMVGIESFAGGERLTRRTVGGLLVGFTGILLLVWPDLTRALTATSGWTWVGGLVSTQLACIGWSVGSTISKQRLKDTDPLVASAFQMLAGGLVMLLVAAVLGEYGRLAWTPRTLAAVVYLFFAGSLIGFVAYTYALRHLPMSTVSLYPYVNPVVAVILGTWLLHEPLTWRIVAAIAIILAGSAVVSRRPKAIQNSEFRIERDATALGSAAALRVQGSE
>NZ_CP015136.1|WP_110174344.1|7351413_7351950_+|Lrp/AsnC-family-transcriptional-regulator
MALIDRTLDTIELRLLGMLQDYARVSQADMARTVGLAPSAVLERLRKLEARGVIRGFAAVLDPRAVDLGQLAFVAVRVSGSGEQEENAGARLAAVPEVLEVHHVAGEDCYLLKVRTRDAQHLGALLRQRLGRIPGVVSTRTTVVLETVKETSRLPLETRTDLKAVQGHEAVADVEVTP
>NZ_CP015136.1|WP_110174343.1|7350539_7351130_-|CHRD-domain-containing-protein
MNRIGAALALMLAVTAPAQAAVIVYSTNLTDALEPNPSPATGFAMVTIDDVANTMRVQASFSGLLGNSTASHIHVINGPGDANTADQNGPVATTTPTFAGFPLGVTSGIYDQTFSLTASGSYNPAFVTAAGGTVPQARVAFLQGLDDERAYFQIHSSVALGGEIRGFLEAQDVPEPTSLTLAGLALAGLFLRRRSR
>NZ_CP015136.1|WP_157899894.1|7350064_7350301_+|hypothetical-protein
MAHPVPESRLVSPDVHCAHLRHKGMYVLTTPDPGEQKHAGNWDATAYWCTQTQKAMGPDGSPANASCCVSGNGRGCCH
>NZ_CP015136.1|WP_110174341.1|7349073_7350054_+|xanthine-dehydrogenase-family-protein-subunit-M
MKPFAYVKAANEQQALAALGRERGKVMPLAGGMDLVSLLKDRIATPDRLVNVKGLDATIAATPDGGLRIGAAVRLVDLQAHGAVTSQYGALMQAAAEVGTPQIRNLGTVGGNLMQRPRCWYFRNEDFPCLKKGGARCYSVDGENQFHAILGGGPCHIVHPSSLAVPLVAFGAKLRIAGPRGEKEVLAEEFFELPERNLFGETSLRPDELLTHVILPAAKAIKSATYEVRFRSSHDWPIAFASVALQLQGTTVSDARVVLGAVAPIPWRSPEAEAVLKGQTLNEATAAKAADAALAAATPMTQNAYKVQVAKTAVKRALLHAAGVTA
>NZ_CP015136.1|WP_157899897.1|7357917_7358709_-|hypothetical-protein
MRLRTAVVALALVACADAASADVKMVAQMTGKMMGRSPSGETVTYIKGAKMRTDQTMGGNQLSTIMDVEAGELISINHKNKEVEIWNIADLAKTMQSTGIAASGVDVKITPNGTSKEIAGYKADGHDMTVSVKSQMAEGMAMTVTISGPAYLSTDAPGAKDYASFYVAAADKGFFFGDPRAAKAQPGNAKGMMALYRTMAEKGIPLESRQVIKLSGDGPMAGIFAKMGGGEINSTVTSVSAEPLGDDIFAVPAGYKVKRQKLD
>NZ_CP015136.1|WP_110174352.1|7358858_7360253_+|MBL-fold-metallo-hydrolase
MSEITFLGAAQTVTGSRHLLRTNAGRRVLVDCGLFQGLKVLRERNWQELGVVPSSLDAVLLTHAHLDHVGWLPRLVAAGYRGRVYCTPGTRDLCTLVLPDAGRLQEEDARQANKHHYTRHAPARPLFTEDDARRALTLLQPVGFGVPLQVVPGLTAEFIRAGHLLGSSFIRVTQDDAPRTILFGGDLGRYDRPVLPDPTPVAEADVLLIESTYGNRTHEPDDDGASLAGVIVRTYEHGGRLVIPSFAIGRVEELLYWLQRLENDARIPSMPTYVDSPMAAEAINFYSSRPDELDPEMRPAHRGPMFDTRRLHVIKDTEESKALTRSSGPAIIISSSGMATGGRVLHHLKHMLPDPKNTVLFVGFQAAGTRGRLLVDGAKTVKIHGEVIPVAARVVKNDQMSAHADRDEMLRWLRGFSRPPAQTFLVHGEPDAMGALASAIRQELGWSVQQPQHREHVILAAASA
>NZ_CP015136.1|WP_110174353.1|7360249_7362214_+|peptidase-M49
MTDIPYLLERVGPAAVVQLHAEAFARLCLRDKCLAWHLYEAALSGRDIYYDQRYEHGLVMRGVIEALFVGRASLEPAVAAAIERYTRLFWINSGPYEHITSRKFVLELSRVQLLAAIEAVRASGQFVPLDSHATPLAFVDAHARDFLDETWRPMVTSKTPAPGEDILAASANNLYAGVSSTDVEGFEERFALNSRLSKEPDGALREDVYRVGGRYGATLARVVAHLEAACAVAPPATRAALEALIRFYRSGEEQDRREYDIAWVADTACAVDTINGFIEVYLDARGRKGAWEGIVFHENPEKTADIRRIAQHAAWFEAHMPYDQAYRRTDVVGVSARAIDVIVECGDAGPMTAIGINLPNDEALREVYGSKSVSLANVSEAYEKSQPESLRAEFCWSDEERERSRRWQALAGELTTSLHEVIGHGSGRMAPQVGSPQTVLREQYSTLEETRSDLVALHFIADPVMVELGLIDAADHVDVVRAEYEGYARNALVQLRRVRKGTHLEEDHMRNRQAIVHWLMAHTSAIERRQRDGRTFYVVVDDEAFREGVGRMLALVQRIKSEGLYDEAVALLDAHGIHFDPVLRDEVVARVDRLDLPSYTGFVMPRLAPVLDTTGAITDVEVSYPLDLATQMLEYADRYGMADEDRRVLATSTA
>NZ_CP015136.1|WP_162472871.1|7362353_7364585_+|peptidylprolyl-isomerase
MVLAHVWLGTTALAQAQAPAIDVRTAILQADDARITSAAPRAVIDTVLASGTAEAQVMAVRAIGRTRRAEFLGPAVRALDNQSIDVRREAAFAVAHIGSADGSTHAAALDALRQRLTRETDPFVTASLAESIGRLSFPSVASVDAAAGVLAGAWARANASPARAVVSVGVARGTEAMARRVRTLAGTGSDSPGLVALLESLLDRHAPPTPGTVALQDVLDRRVRRLATTGLMTLRSLSAPRRVAAAGDADAQVRRLAVIDLSSRPEVSDADAADAFSDESMLVRHAAVSRLGSRLPTRAEVAVSDRHVSVRLAALDALGEAHACRSACETRLVTTPTGANWHEYAHALVAAARTDAAAARPLVARAASSDVWQVRMYAGRAAGTTLQADVLGALSADTDVNVRHAALAAWREAKLPNLTAAALDALGSDDGQLVIEAANALRGTGADRGTVTALRAALARLTAQKRETSRDPRVALIERIDELDAERATTLRPYLSDFDPFIAERVTALLRTRGVGLPDDSPGSPLARRSLGAGGSPANAGPRSENGPYRSTSAGAADSPIPPTWNDVTRLQGTTVTLTFSGNRTLTFRLYAELAPTAVARFVAQVNRGEWNGRTFHRVEPGFVVQGGSPAANEYAGAADFARDEFSSLSHVRGTIGISTRGPDTGDGQIFINLVDNARLDFAYTVLGSLTGDSGLIDDIVEGEAIESATVVRPVAADRRTSPAATCLAPGVGVGPCPTHGAP
>NZ_CP015136.1|WP_157899899.1|7364560_7365862_+|threonine/serine-exporter-family-protein
MSDAWSAVMGADMPVAPSSGAPYSDEEAAAVGFVLRLGRALHGYGLSADALEYNLQAMSDRLGLEANFFTTPTSIFAAFGPPERQHTHLIRVFPGDVDLGKLARLDAVSRDVEQHRLTVIEGSRRIDEIIALPPISRPVVRVLGYGVASAVVCRILGGGINEVLVAGFAGLLTGAISLASNRLPHGTHVFELVAAFAVSLVVTCFAAISDLRLSVPTATLGGVIVLVPGLTVTVAMTELARRHLAAGTARLSGAFLVFVTIAFGVAVGAEVAGALVGEVRSLQPRRLPDWTLTLAVAVAPLAFGVLLRARLRDFPWLWLSSAIGYTAVRLAALSFGPAMAASIGALVVGVLANLYDRRGLGPAAVAQVPGVLLLVPGSIGYRSLSSLLDQNVIVGVTAAFTMILTAVAIAAGLLVASVLVPTHRQRETTRPSA
>NZ_CP015136.1|WP_110174356.1|7366368_7366686_+|hypothetical-protein
MHTVLFYVQHDNEVPILVPVEVVSREPDRLGHLRLVEPLKLKDAVVETVPLTRCYEYDPYLAHAVQAYAAQVTTLVRVSQSVIEGLAIPVTAPKGTYMQPDARVH
>NZ_CP015136.1|WP_110174357.1|7366767_7367004_-|DUF4926-domain-containing-protein
MTPNLLDVVVLNCDLPAHGLRRGDLGAVVDAPGPGAIVVEFVAASGRTQALVTLAPADVRAVADDDLVAVRSAAPKAS
>NZ_CP015136.1|WP_110174358.1|7367000_7367342_-|hypothetical-protein
MRLPNAERALIDRTKLEGYLLSTAHPIGRFKARFFAALGFTADHWEVLEEALREQHLHQDAEAGVQDEQGQRFSIRAILRGPTGASEMMVSVWFMRTGEDHARFVTAYPGETK
>NZ_CP015136.1|WP_110174359.1|7367322_7368882_-|deoxyribodipyrimidine-photolyase
MSLNNPKLLVAAPASRVRVLRDAPPRRAARYVLYWMIAARRLEDNFALQHAAWWASELDLPLLIFEPLRVGYPWASDRLHAFVLQGMSEHRAAAGRLGVTYFAYVEPRPDAGKGVLRRLAADAAVVVTDDYPTFFLPRMIAAAAARLDCRLEAVDGNGLLPMRATSTVYPTAYAFRRYVQKALPAQLMQFPVRSPLEVLPRRAAPVAAEVLERWPPANDTLLRATAEGLATLPIDHSVAPSPVLTGGSTAAHVRLEEFIAHGLGRYDERNQPDSDGASGLSPWLHFGHIAAHRIFSDVASHAGWTSRQLAARGNGNREGWWGASPQVEAFLDELITWRELGFNFAANRADYDRYESLPEWARASLDAHAADRREHLYTLQQFERAETHDPVWNAAQRQLVREGRIHNYLRMLWGKKILHWTPDPREALAVMIELNNKYALDGRDPNSYSGIFWVLGRYDRPWAPRREVFGVIRYMSSENTARKLRLKNYLRTYGPDAPLPGLDPCDPDDGRMRRASSEC
>NZ_CP015136.1|WP_110174360.1|7369500_7369758_+|hypothetical-protein
MESRRSALEGWTPEQLALGRAWAATWRDAGPRLEAIRRQELRALDAFAAIALLCGAADYQLPPRAPAPTSGLLEQQRLFMRLRPL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015136_7	7.1\|7112928\|24\|NZ_CP015136\|CRISPRCasFinder	7112928-7112951	24	NZ_CP020505	Serratia marcescens strain 95 plasmid unnamed2, complete sequence	47815-47838	3	0.875
NZ_CP015136_7	7.1\|7112928\|24\|NZ_CP015136\|CRISPRCasFinder	7112928-7112951	24	CP049262	Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence	82494-82517	3	0.875
NZ_CP015136_7	7.1\|7112928\|24\|NZ_CP015136\|CRISPRCasFinder	7112928-7112951	24	NZ_CP026400	Escherichia coli strain ECONIH4 plasmid pECO-5e72, complete sequence	50137-50160	3	0.875
NZ_CP015136_7	7.1\|7112928\|24\|NZ_CP015136\|CRISPRCasFinder	7112928-7112951	24	NZ_CP022158	Escherichia coli strain ABWA45 plasmid pABWA45_4, complete sequence	6453-6476	3	0.875
NZ_CP015136_7	7.1\|7112928\|24\|NZ_CP015136\|CRISPRCasFinder	7112928-7112951	24	NZ_MF062700	Enterobacter cloacae strain T5282 plasmid pT5282-CTXM, complete sequence	19051-19074	3	0.875
NZ_CP015136_7	7.1\|7112928\|24\|NZ_CP015136\|CRISPRCasFinder	7112928-7112951	24	NC_048130	Klebsiella phage KN4-1 DNA, complete genome	5372-5395	3	0.875
NZ_CP015136_9	9.1\|7357852\|32\|NZ_CP015136\|CRISPRCasFinder	7357852-7357883	32	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	370908-370939	7	0.781

1. spacer 7.1|7112928|24|NZ_CP015136|CRISPRCasFinder matches to NZ_CP020505 (Serratia marcescens strain 95 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.875

tacagcccattcatcgcctcgacc	CRISPR spacer
cacagctcattcatcgcctccacc	Protospacer
.*****.************* ***

2. spacer 7.1|7112928|24|NZ_CP015136|CRISPRCasFinder matches to CP049262 (Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence) position: , mismatch: 3, identity: 0.875

tacagcccattcatcgcctcgacc	CRISPR spacer
cacagctcattcatcgcctccacc	Protospacer
.*****.************* ***

3. spacer 7.1|7112928|24|NZ_CP015136|CRISPRCasFinder matches to NZ_CP026400 (Escherichia coli strain ECONIH4 plasmid pECO-5e72, complete sequence) position: , mismatch: 3, identity: 0.875

tacagcccattcatcgcctcgacc	CRISPR spacer
cacagctcattcatcgcctccacc	Protospacer
.*****.************* ***

4. spacer 7.1|7112928|24|NZ_CP015136|CRISPRCasFinder matches to NZ_CP022158 (Escherichia coli strain ABWA45 plasmid pABWA45_4, complete sequence) position: , mismatch: 3, identity: 0.875

tacagcccattcatcgcctcgacc	CRISPR spacer
cacagctcattcatcgcctccacc	Protospacer
.*****.************* ***

5. spacer 7.1|7112928|24|NZ_CP015136|CRISPRCasFinder matches to NZ_MF062700 (Enterobacter cloacae strain T5282 plasmid pT5282-CTXM, complete sequence) position: , mismatch: 3, identity: 0.875

tacagcccattcatcgcctcgacc	CRISPR spacer
cacagctcattcatcgcctccacc	Protospacer
.*****.************* ***

6. spacer 7.1|7112928|24|NZ_CP015136|CRISPRCasFinder matches to NC_048130 (Klebsiella phage KN4-1 DNA, complete genome) position: , mismatch: 3, identity: 0.875

tacagcccattcatcgcctcgacc	CRISPR spacer
ttcagccaattcatcgcctcgaca	Protospacer
* ***** ***************

7. spacer 9.1|7357852|32|NZ_CP015136|CRISPRCasFinder matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 7, identity: 0.781

cccgagtccgtatcgtggcggtgctcggaccc	CRISPR spacer
accaggtccgtatcgtgccggtggtcggagac	Protospacer
 **..************ ***** *****  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1475839 : 1553020

Bacillus_phage(50.0%)

plate,tRNA,protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_110169929.1\|1475839_1476256_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_110169930.1\|1476563_1476992_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_110169931.1\|1477084_1478290_-	amidohydrolase	NA	NA	NA	NA
WP_157898801.1\|1478463_1478868_+	hypothetical protein	NA	NA	NA	NA
WP_110169933.1\|1479105_1482177_-	TonB-dependent receptor	NA	NA	NA	NA
WP_157898802.1\|1482528_1483083_-	hypothetical protein	NA	NA	NA	NA
WP_110169935.1\|1483483_1484353_+	ATP-dependent sacrificial sulfur transferase LarE	NA	NA	NA	NA
WP_110169936.1\|1484357_1485161_+	nickel pincer cofactor biosynthesis protein LarB	NA	NA	NA	NA
WP_110169937.1\|1485157_1486528_+	LarC family nickel insertion protein	NA	NA	NA	NA
WP_110169938.1\|1486806_1487436_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_157898803.1\|1487532_1489860_-	VWA domain-containing protein	NA	NA	NA	NA
WP_110169940.1\|1490044_1492366_-	VWA domain-containing protein	NA	NA	NA	NA
WP_157898804.1\|1492520_1493393_+	subclass B3 metallo-beta-lactamase	NA	NA	NA	NA
WP_110169942.1\|1493575_1495057_-\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	2.0e-23	28.2
WP_110169943.1\|1495123_1496542_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.8e-22	27.4
WP_110169944.1\|1496522_1497197_-	response regulator transcription factor	NA	NA	NA	NA
WP_157898805.1\|1497600_1497927_+\|transposase	transposase	NA	NA	NA	NA
WP_110174556.1\|1498560_1499490_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_110169946.1\|1499603_1502075_-	glycoside hydrolase family 127 protein	NA	NA	NA	NA
WP_110169947.1\|1502235_1502529_+	YggU family protein	NA	NA	NA	NA
WP_110174557.1\|1502542_1504549_+	TonB-dependent receptor	NA	NA	NA	NA
WP_110169948.1\|1504639_1506124_+	hypothetical protein	NA	NA	NA	NA
WP_110169949.1\|1506191_1506731_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_157898806.1\|1506727_1507183_+	hypothetical protein	NA	NA	NA	NA
WP_157898807.1\|1507179_1508958_+	RDD family protein	NA	NA	NA	NA
WP_157898808.1\|1509080_1509674_+	hypothetical protein	NA	NA	NA	NA
WP_157898809.1\|1509681_1510461_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_110169953.1\|1510642_1514041_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_110169954.1\|1514183_1515542_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_110169955.1\|1515658_1515859_+	hypothetical protein	NA	NA	NA	NA
WP_110169956.1\|1515904_1517308_+	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_157898810.1\|1517358_1517976_-	YceI family protein	NA	NA	NA	NA
WP_110169958.1\|1518199_1518706_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_110169959.1\|1518831_1520775_-	alkaline phosphatase	NA	NA	NA	NA
WP_110169960.1\|1520822_1521962_+	alkaline phosphatase	NA	NA	NA	NA
WP_110169961.1\|1522024_1523230_+	D-2-hydroxyacid dehydrogenase	NA	NA	NA	NA
WP_157898811.1\|1523333_1524314_+	TIM barrel protein	NA	NA	NA	NA
WP_157898812.1\|1524327_1525485_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_110169964.1\|1525590_1526544_+	TIM barrel protein	NA	NA	NA	NA
WP_110169965.1\|1526714_1527989_-	succinylglutamate desuccinylase/aspartoacylase family protein	NA	NA	NA	NA
WP_162472880.1\|1531091_1532714_+	response regulator	A0A1V0SGX0	Hokovirus	5.3e-33	29.3
WP_110169967.1\|1532722_1533097_+	response regulator	W8CYM9	Bacillus_phage	1.2e-17	39.5
WP_110169968.1\|1533096_1534680_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_157898813.1\|1534732_1535131_-	DUF1801 domain-containing protein	NA	NA	NA	NA
WP_110169970.1\|1535242_1536742_+	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_110169971.1\|1536778_1538110_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_110169972.1\|1538124_1539423_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_110169973.1\|1539456_1542921_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_110169974.1\|1542893_1544399_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_110169975.1\|1544624_1545647_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_110169976.1\|1545669_1546185_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_110169977.1\|1546212_1547709_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_110169978.1\|1547763_1548240_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_110169979.1\|1548288_1548768_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_110169980.1\|1548764_1549613_+	virulence protein SciE type	NA	NA	NA	NA
WP_110169981.1\|1549605_1550127_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_110169982.1\|1550129_1552010_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_110169983.1\|1551973_1553020_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_2

1937270 : 1984663

Mycoplasma_phage(28.57%)

plate,protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_110170251.1\|1937270_1940234_-\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_110174581.1\|1940230_1942597_-\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_110170252.1\|1942640_1942997_-	GPW/gp25 family protein	NA	NA	NA	NA
WP_110170253.1\|1943009_1943330_-	hypothetical protein	NA	NA	NA	NA
WP_110170254.1\|1943329_1943842_-\|plate	baseplate assembly protein	NA	NA	NA	NA
WP_110170255.1\|1943873_1945007_-	hypothetical protein	NA	NA	NA	NA
WP_110170256.1\|1944999_1945323_-	LysM domain-containing protein	NA	NA	NA	NA
WP_110170257.1\|1945319_1945970_-	hypothetical protein	NA	NA	NA	NA
WP_110170258.1\|1945966_1946482_-	hypothetical protein	NA	NA	NA	NA
WP_110170259.1\|1946478_1948560_-	hypothetical protein	NA	NA	NA	NA
WP_110170260.1\|1948564_1951288_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_110170261.1\|1951284_1951560_-	hypothetical protein	NA	NA	NA	NA
WP_110170262.1\|1951559_1953515_-	ATP-binding protein	A0A109WUE1	Acidianus_tailed_spindle_virus	7.1e-08	34.1
WP_110170263.1\|1953511_1954777_-	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_110170264.1\|1954773_1955490_-	hypothetical protein	NA	NA	NA	NA
WP_110170265.1\|1955498_1956245_-	hypothetical protein	NA	NA	NA	NA
WP_110170266.1\|1956244_1956766_-\|tail	phage tail protein	NA	NA	NA	NA
WP_110170267.1\|1956779_1958387_-\|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	2.1e-50	32.3
WP_110170268.1\|1958573_1959707_+	hypothetical protein	NA	NA	NA	NA
WP_110170269.1\|1959720_1960035_+	hypothetical protein	NA	NA	NA	NA
WP_110170270.1\|1960116_1962573_-	ABC transporter permease	NA	NA	NA	NA
WP_162271327.1\|1962756_1964694_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_110170272.1\|1964743_1965241_-	ATP-binding protein	A0A2K9L5I4	Tupanvirus	3.2e-13	34.0
WP_110170273.1\|1965671_1966619_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_110170274.1\|1966615_1967611_-	aldo/keto reductase	NA	NA	NA	NA
WP_110170275.1\|1967678_1968458_-	phosphate ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_110170276.1\|1968454_1969216_-	ATP-binding cassette domain-containing protein	A0A2H4UU96	Bodo_saltans_virus	4.7e-08	24.4
WP_110170277.1\|1969227_1970112_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_110174582.1\|1970115_1971015_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_110170278.1\|1971035_1971971_-	phosphate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_110170279.1\|1971976_1973080_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_157898883.1\|1973235_1973457_+	hypothetical protein	NA	NA	NA	NA
WP_110170281.1\|1973512_1973749_-	DUF892 family protein	NA	NA	NA	NA
WP_110170282.1\|1973905_1975750_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_110170283.1\|1975752_1976595_-	ABC transporter permease	Q6GZ02	Mycoplasma_phage	1.2e-09	24.5
WP_110170284.1\|1976591_1977668_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.1e-26	35.6
WP_110170285.1\|1977803_1978040_-	zf-HC2 domain-containing protein	NA	NA	NA	NA
WP_110170286.1\|1978036_1978525_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_110174583.1\|1978851_1979166_+	MOSC N-terminal beta barrel domain-containing protein	NA	NA	NA	NA
WP_157898884.1\|1979181_1979355_+	hypothetical protein	NA	NA	NA	NA
WP_110170287.1\|1979395_1979806_-	ester cyclase	NA	NA	NA	NA
WP_157898885.1\|1980011_1980269_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_110174584.1\|1980294_1981245_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_110170289.1\|1981410_1982298_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_162271328.1\|1982566_1983328_-	slipin family protein	J3IZE5	Acanthamoeba_polyphaga_lentillevirus	2.8e-21	28.6
WP_162271329.1\|1983337_1984663_-\|protease	ATP-dependent Clp protease proteolytic subunit	NA	NA	NA	NA

DBSCAN-SWA_3

2066128 : 2122572

Synechococcus_phage(25.0%)

integrase,transposase

attL 2091357:2091374|attR 2126912:2126929

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_110170347.1\|2066128_2066440_+\|transposase	transposase	NA	NA	NA	NA
WP_157898901.1\|2066996_2067215_-	hypothetical protein	NA	NA	NA	NA
WP_162271333.1\|2067234_2067663_-	hypothetical protein	NA	NA	NA	NA
WP_110170350.1\|2067836_2070104_+	PD40 domain-containing protein	NA	NA	NA	NA
WP_157898902.1\|2070315_2070810_+\|transposase	transposase	NA	NA	NA	NA
WP_162271334.1\|2070970_2072065_-	TIR domain-containing protein	NA	NA	NA	NA
WP_110170353.1\|2072411_2072738_+	hypothetical protein	NA	NA	NA	NA
WP_162271335.1\|2073286_2075410_-	PD40 domain-containing protein	NA	NA	NA	NA
WP_110174592.1\|2075486_2076038_-	hypothetical protein	NA	NA	NA	NA
WP_110170356.1\|2076298_2076865_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_110170357.1\|2077177_2078104_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_110170358.1\|2079655_2080543_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_110170359.1\|2081901_2083023_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_110170360.1\|2083031_2083499_+	hypothetical protein	NA	NA	NA	NA
WP_110170361.1\|2083532_2084549_+	zinc-dependent alcohol dehydrogenase family protein	E3SJ82	Synechococcus_phage	1.3e-05	25.0
WP_110170362.1\|2085126_2085531_+	cupin domain-containing protein	NA	NA	NA	NA
WP_110170363.1\|2086245_2086881_-	hypothetical protein	NA	NA	NA	NA
WP_157898903.1\|2088097_2088430_+	hypothetical protein	NA	NA	NA	NA
WP_157898904.1\|2088465_2088795_-	hypothetical protein	NA	NA	NA	NA
WP_110170365.1\|2089861_2090005_+	DUF3309 domain-containing protein	NA	NA	NA	NA
WP_157898905.1\|2090020_2090188_-	hypothetical protein	NA	NA	NA	NA
WP_110170367.1\|2090687_2091659_-	ThuA domain-containing protein	NA	NA	NA	NA
2091357:2091374	attL	NA	NA	NA	NA
WP_110174593.1\|2091750_2092824_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_110170368.1\|2093087_2096603_-	carboxypeptidase regulatory-like domain-containing protein	NA	NA	NA	NA
WP_157898906.1\|2097244_2097583_+	hypothetical protein	NA	NA	NA	NA
WP_110170371.1\|2097558_2098329_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.0e-06	33.1
WP_110170372.1\|2099121_2099415_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_110170373.1\|2099822_2101985_-	PQQ-dependent dehydrogenase, methanol/ethanol family	NA	NA	NA	NA
WP_169812006.1\|2102048_2102936_-	hypothetical protein	NA	NA	NA	NA
WP_110170375.1\|2102977_2103628_+	BBE domain-containing protein	NA	NA	NA	NA
WP_110170376.1\|2104006_2104249_+	hypothetical protein	NA	NA	NA	NA
WP_110174594.1\|2104359_2104863_-	DinB family protein	NA	NA	NA	NA
WP_110170377.1\|2106016_2106160_+	DUF3309 domain-containing protein	NA	NA	NA	NA
WP_110170378.1\|2106186_2106552_-\|transposase	transposase	Q8W6R2	Burkholderia_virus	8.8e-13	49.3
WP_110170379.1\|2107246_2109922_+	serine/threonine-protein kinase	M1PCM5	Moumouvirus	1.6e-15	25.3
WP_110170380.1\|2110067_2110499_+	hypothetical protein	NA	NA	NA	NA
WP_110170381.1\|2111107_2111920_-	hypothetical protein	NA	NA	NA	NA
WP_157898907.1\|2112790_2114695_+	PD40 domain-containing protein	NA	NA	NA	NA
WP_110174595.1\|2114948_2115794_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_110170383.1\|2117731_2118445_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_110174596.1\|2119031_2120813_+	recombinase family protein	NA	NA	NA	NA
WP_110170384.1\|2120782_2121232_-	hypothetical protein	NA	NA	NA	NA
WP_157898908.1\|2121657_2122572_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
2126912:2126929	attR	NA	NA	NA	NA

DBSCAN-SWA_4

3229073 : 3305110

Orpheovirus(22.22%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_110171194.1\|3229073_3229721_+\|transposase	transposase	NA	NA	NA	NA
WP_110171195.1\|3230065_3232636_+	serine/threonine-protein kinase	A0A2I2L395	Orpheovirus	1.9e-13	25.0
WP_110171196.1\|3232641_3233235_-	hypothetical protein	NA	NA	NA	NA
WP_157899120.1\|3233336_3234056_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_110171198.1\|3234526_3235669_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_110174670.1\|3235679_3236714_-	TIM barrel protein	NA	NA	NA	NA
WP_157899121.1\|3237143_3237320_-	hypothetical protein	NA	NA	NA	NA
WP_157899122.1\|3238147_3240565_-	protein kinase	G9BWE0	Planktothrix_phage	8.7e-16	31.8
WP_110171200.1\|3240670_3241024_-	hypothetical protein	NA	NA	NA	NA
WP_110171201.1\|3240975_3241176_-	hypothetical protein	NA	NA	NA	NA
WP_157899124.1\|3241434_3242196_+	VOC family protein	NA	NA	NA	NA
WP_157899125.1\|3242750_3243284_+	DUF4440 domain-containing protein	NA	NA	NA	NA
WP_157899126.1\|3243285_3243543_-	hypothetical protein	NA	NA	NA	NA
WP_162271378.1\|3244039_3244495_-	hypothetical protein	NA	NA	NA	NA
WP_157899128.1\|3245093_3245723_-	peptidase dimerisation domain-containing protein	NA	NA	NA	NA
WP_110171206.1\|3246111_3246636_+\|transposase	transposase	NA	NA	NA	NA
WP_162271379.1\|3247239_3248415_-	phosphatase PAP2 family protein	A0A1V0SKZ4	Klosneuvirus	3.4e-13	25.2
WP_162271380.1\|3248629_3251572_-	serine/threonine-protein kinase	A0A2H4UVE2	Bodo_saltans_virus	2.0e-14	26.8
WP_110171209.1\|3251568_3252135_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_110171210.1\|3252494_3253442_+	hypothetical protein	NA	NA	NA	NA
WP_157899129.1\|3253557_3254082_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_157899130.1\|3254166_3254394_-	hypothetical protein	NA	NA	NA	NA
WP_162271381.1\|3255001_3256693_-	PD40 domain-containing protein	NA	NA	NA	NA
WP_157899132.1\|3257440_3257998_+	hypothetical protein	NA	NA	NA	NA
WP_110171214.1\|3258792_3259008_+	hypothetical protein	NA	NA	NA	NA
WP_110171215.1\|3259966_3261175_-	TIR domain-containing protein	NA	NA	NA	NA
WP_157899133.1\|3261171_3262695_-	peptidoglycan-binding protein	NA	NA	NA	NA
WP_110171217.1\|3262973_3263918_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	7.3e-43	36.4
WP_157899134.1\|3263907_3264072_-	hypothetical protein	NA	NA	NA	NA
WP_157899135.1\|3264546_3265431_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_110171219.1\|3265972_3266509_-	hypothetical protein	NA	NA	NA	NA
WP_110171220.1\|3266690_3268433_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_110171221.1\|3268606_3269407_+	isochorismatase family protein	NA	NA	NA	NA
WP_157899136.1\|3269595_3270381_+	hypothetical protein	NA	NA	NA	NA
WP_157899137.1\|3270581_3271163_+	hypothetical protein	NA	NA	NA	NA
WP_110171224.1\|3271249_3271795_+	hypothetical protein	NA	NA	NA	NA
WP_110171225.1\|3272035_3274306_+	PD40 domain-containing protein	NA	NA	NA	NA
WP_110171226.1\|3274677_3274905_+	hypothetical protein	NA	NA	NA	NA
WP_110171227.1\|3275125_3276706_-	tannase/feruloyl esterase family alpha/beta hydrolase	NA	NA	NA	NA
WP_157899138.1\|3277415_3278258_-	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_157899928.1\|3278366_3278678_-	hypothetical protein	NA	NA	NA	NA
WP_157899139.1\|3278843_3279542_-	PD40 domain-containing protein	NA	NA	NA	NA
WP_162271382.1\|3279566_3281831_-	serine/threonine-protein kinase	A0A2I2L395	Orpheovirus	2.8e-16	28.8
WP_110174673.1\|3281820_3282399_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_110171231.1\|3282579_3283077_+	SgcJ/EcaC family oxidoreductase	NA	NA	NA	NA
WP_162271383.1\|3283095_3284118_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_162271384.1\|3284749_3286942_-	PD40 domain-containing protein	NA	NA	NA	NA
WP_157899140.1\|3287588_3288089_-	hypothetical protein	NA	NA	NA	NA
WP_110171235.1\|3288285_3289179_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.3e-20	34.6
WP_110171236.1\|3289175_3292796_+	hypothetical protein	NA	NA	NA	NA
WP_157899141.1\|3293207_3293522_+\|transposase	transposase	NA	NA	NA	NA
WP_162271385.1\|3294749_3296195_-	FAD-binding oxidoreductase	S4VRT3	Pandoravirus	4.2e-34	40.3
WP_110171240.1\|3297762_3300765_+	protein kinase	V5L5T2	Insectomime_virus	3.7e-16	28.0
WP_110174674.1\|3300774_3301485_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_110171241.1\|3301773_3302496_+	hypothetical protein	NA	NA	NA	NA
WP_157899142.1\|3302901_3303867_+	PD40 domain-containing protein	NA	NA	NA	NA
WP_157899143.1\|3304167_3304338_+\|transposase	transposase	NA	NA	NA	NA
WP_157899144.1\|3304342_3305110_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

3320039 : 3360741

Enterobacteria_phage(37.5%)

integrase,transposase

attL 3311834:3311861|attR 3368225:3368252

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3311834:3311861	attL	NA	NA	NA	NA
WP_110171258.1\|3320039_3320390_+\|transposase	transposase	Q1MVF0	Enterobacteria_phage	9.3e-12	44.4
WP_110174676.1\|3321107_3322823_-	asparaginase	NA	NA	NA	NA
WP_157899151.1\|3322846_3324352_-	tannase/feruloyl esterase family alpha/beta hydrolase	NA	NA	NA	NA
WP_110171260.1\|3324769_3325351_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_110171261.1\|3325343_3328283_+	protein kinase	G9BWE0	Planktothrix_phage	3.2e-12	27.2
WP_110174677.1\|3328644_3330120_-	purine permease	Q9KX94	Enterobacteria_phage	6.1e-28	27.3
WP_157899152.1\|3332091_3333003_+	protein phosphatase 2C domain-containing protein	NA	NA	NA	NA
WP_157899153.1\|3333346_3335467_-	PD40 domain-containing protein	NA	NA	NA	NA
WP_157899154.1\|3335650_3336904_+	vanadium-dependent haloperoxidase	NA	NA	NA	NA
WP_110171264.1\|3337214_3337613_+\|transposase	transposase	NA	NA	NA	NA
WP_110171266.1\|3338404_3340363_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_157899155.1\|3340523_3341111_+	hypothetical protein	NA	NA	NA	NA
WP_110171268.1\|3341104_3341314_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2L1IVA1	Escherichia_phage	8.6e-05	45.5
WP_110171269.1\|3341254_3341470_+	hypothetical protein	NA	NA	NA	NA
WP_162271388.1\|3341725_3342868_-	methyltransferase	NA	NA	NA	NA
WP_110171270.1\|3342832_3343825_+\|transposase	transposase	Q1MVF0	Enterobacteria_phage	1.5e-22	41.8
WP_110171271.1\|3343770_3344298_+\|transposase	transposase	NA	NA	NA	NA
WP_110171272.1\|3344332_3345739_+	serine/threonine protein kinase	M1PCM5	Moumouvirus	2.2e-11	31.1
WP_157899158.1\|3345848_3345992_+	hypothetical protein	NA	NA	NA	NA
WP_157899159.1\|3346145_3347747_-	carboxylesterase family protein	A0A0G2Y6W1	Acanthamoeba_polyphaga_mimivirus	2.3e-25	35.7
WP_157899160.1\|3348134_3348362_-	amidohydrolase family protein	NA	NA	NA	NA
WP_110171275.1\|3348294_3349377_-	amidohydrolase family protein	NA	NA	NA	NA
WP_110171276.1\|3351040_3351598_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_157899161.1\|3351696_3352215_+	hypothetical protein	NA	NA	NA	NA
WP_110171278.1\|3352238_3355106_-	protein kinase	A0A2K9L111	Tupanvirus	9.7e-14	24.6
WP_162271389.1\|3355905_3358374_-	Ig-like domain repeat protein	NA	NA	NA	NA
WP_110171280.1\|3359166_3360741_+\|transposase	IS21 family transposase	NA	NA	NA	NA
3368225:3368252	attR	NA	NA	NA	NA

DBSCAN-SWA_6

4537957 : 4602174

uncultured_Mediterranean_phage(20.0%)

protease,head,capsid,integrase

attL 4588789:4588837|attR 4598273:4598321

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_110172158.1\|4537957_4538164_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_157899382.1\|4538102_4538741_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_110172160.1\|4539224_4539902_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_157899383.1\|4539916_4540063_+	hypothetical protein	NA	NA	NA	NA
WP_157899384.1\|4540067_4540220_+	hypothetical protein	NA	NA	NA	NA
WP_110172161.1\|4540430_4540649_-	DUF4062 domain-containing protein	NA	NA	NA	NA
WP_110172162.1\|4541479_4541839_-	hypothetical protein	NA	NA	NA	NA
WP_110172164.1\|4542496_4542826_+	DMT family protein	NA	NA	NA	NA
WP_157899385.1\|4542864_4543344_-	DUF3592 domain-containing protein	NA	NA	NA	NA
WP_110172166.1\|4543694_4545083_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_110172167.1\|4545079_4545634_+	PAS domain-containing protein	NA	NA	NA	NA
WP_110172168.1\|4545740_4545983_-	CsbD family protein	NA	NA	NA	NA
WP_110172169.1\|4545979_4546732_-	BON domain-containing protein	NA	NA	NA	NA
WP_110174767.1\|4546980_4547577_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_110172170.1\|4547576_4549478_+	cation:proton antiporter	NA	NA	NA	NA
WP_157899386.1\|4549497_4550157_+	hypothetical protein	NA	NA	NA	NA
WP_110172172.1\|4550314_4551151_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_157899387.1\|4551176_4551878_-	DUF2892 domain-containing protein	NA	NA	NA	NA
WP_110172174.1\|4552063_4552219_+	lmo0937 family membrane protein	NA	NA	NA	NA
WP_110172175.1\|4552436_4554362_+	malto-oligosyltrehalose trehalohydrolase	NA	NA	NA	NA
WP_110172176.1\|4554358_4556455_+	glycogen debranching enzyme N-terminal domain-containing protein	NA	NA	NA	NA
WP_157899388.1\|4556429_4557824_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_110172178.1\|4558251_4559364_+	glycosyltransferase	NA	NA	NA	NA
WP_157899389.1\|4559438_4559720_-	hypothetical protein	NA	NA	NA	NA
WP_157899390.1\|4560714_4561968_+	BamA/TamA family outer membrane protein	NA	NA	NA	NA
WP_110172181.1\|4561976_4563647_+	hypothetical protein	NA	NA	NA	NA
WP_110172182.1\|4563646_4565032_+	translocase	NA	NA	NA	NA
WP_110172183.1\|4564955_4567190_-	hypothetical protein	NA	NA	NA	NA
WP_110172184.1\|4567199_4568822_-	serine/threonine protein kinase	A0A1B1IUU3	uncultured_Mediterranean_phage	1.3e-12	30.1
WP_157899391.1\|4569163_4572730_+	hypothetical protein	NA	NA	NA	NA
WP_157899392.1\|4572840_4573398_-	DUF937 domain-containing protein	NA	NA	NA	NA
WP_157899393.1\|4573499_4573658_-	hypothetical protein	NA	NA	NA	NA
WP_110172187.1\|4573712_4574672_+	META domain-containing protein	NA	NA	NA	NA
WP_157899394.1\|4574684_4575539_-	maleylpyruvate isomerase family protein	NA	NA	NA	NA
WP_110174768.1\|4575612_4576875_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_110172189.1\|4576924_4577794_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_157899395.1\|4577823_4578921_-	HupE/UreJ family protein	NA	NA	NA	NA
WP_110172191.1\|4579136_4579661_+	DinB family protein	NA	NA	NA	NA
WP_110172192.1\|4579792_4581256_-	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_110172193.1\|4581265_4584457_-	DUF1553 domain-containing protein	NA	NA	NA	NA
WP_162271444.1\|4584583_4587043_-	PAS domain S-box protein	W8CYF6	Bacillus_phage	4.5e-28	30.9
WP_162271445.1\|4587395_4587797_+	hypothetical protein	NA	NA	NA	NA
WP_110172195.1\|4587811_4588036_-	hypothetical protein	NA	NA	NA	NA
WP_157899396.1\|4588416_4588683_-	hypothetical protein	NA	NA	NA	NA
4588789:4588837	attL	NA	NA	NA	NA
WP_110172197.1\|4589051_4590305_+\|integrase	site-specific integrase	A0A1X9SGU9	Bradyrhizobium_phage	2.6e-24	28.8
WP_157899397.1\|4590348_4590987_+	hypothetical protein	NA	NA	NA	NA
WP_157899398.1\|4591033_4591303_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_110172201.1\|4591493_4591706_+	hypothetical protein	NA	NA	NA	NA
WP_110172202.1\|4591692_4593054_+	AAA family ATPase	NA	NA	NA	NA
WP_110172203.1\|4593043_4593520_+	hypothetical protein	NA	NA	NA	NA
WP_157899399.1\|4593522_4593786_+	hypothetical protein	NA	NA	NA	NA
WP_110172205.1\|4593867_4594500_+\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.6e-22	42.5
WP_110172206.1\|4594686_4595922_+\|capsid	phage major capsid protein	R9TPU0	Vibrio_phage	5.8e-08	24.9
WP_110174769.1\|4596121_4596844_+	HXXEE domain-containing protein	NA	NA	NA	NA
WP_157899400.1\|4597047_4597236_+	hypothetical protein	NA	NA	NA	NA
WP_110172208.1\|4597354_4597942_-	hypothetical protein	NA	NA	NA	NA
WP_157899401.1\|4598451_4599144_-	MerR family transcriptional regulator	NA	NA	NA	NA
4598273:4598321	attR	NA	NA	NA	NA
WP_110172210.1\|4599389_4600772_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_110172211.1\|4600832_4601105_+	integration host factor subunit beta	NA	NA	NA	NA
WP_110172212.1\|4601220_4602174_+\|protease	site-2 protease family protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP015136

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection