CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP015345	Alteromonas stellipolaris strain PQQ-42, complete genome	2 crisprs	DEDDh,cas3,csa3,DinG,WYL,RT	2	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015345_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015345_1

2048534-2048696

Orphan

Consensus_repeat	Method
AAAAAACCAACTAAAAAGTTGGCTTAAATGTTTGGTACCAGTGGGCGGACTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015345_1

>merge|NZ_CP015345|1|2048534-2048696|CRISPRCasFinder
AAAAAACCAACTAAAAAGTTGGCTTAAATGTTTGGTACCAGTGGGCGGACTTTGGCTGGGCCGACACTCGGCCGACACGCTTGCGTGGCGATTTCATGAATTTCAGGCACAAAAAAACCAACTAAAAAGTTGGCTTAAATGTTTGGTACCAGTGGGCGGACTT

>NZ_CP015345|1|1|2048534-2048696|CRISPRCasFinder
AAAAAACCAACTAAAAAGTTGGCTTAAATGTTTGGTACCAGTGGGCGGACTT	TGGCTGGGCCGACACTCGGCCGACACGCTTGCGTGGCGATTTCATGAATTTCAGGCACA
AAAAAACCAACTAAAAAGTTGGCTTAAATGTTTGGTACCAGTGGGCGGACTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015345.1\|WP_063456790.1\|2031140_2038610_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293789
NZ_CP015345.1\|WP_057789629.1\|2026167_2029836_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372685
NZ_CP015345.1\|WP_057789646.1\|2048928_2050023_-\|DUF1624-domain-containing-protein	unknown	unknown	gnl\|CDD\|377915
NZ_CP015345.1\|WP_057789630.1\|2029852_2030986_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015345.1\|WP_057789659.1\|2057253_2058627_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240548
NZ_CP015345.1\|WP_057789640.1\|2042100_2045793_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379232
NZ_CP015345.1\|WP_057789661.1\|2058831_2059974_-\|HupE/UreJ-family-protein	unknown	unknown	gnl\|CDD\|379373
NZ_CP015345.1\|WP_082823971.1\|2053549_2054149_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226715
NZ_CP015345.1\|WP_082823972.1\|2054124_2055432_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377237
NZ_CP015345.1\|WP_057789644.1\|2047270_2048368_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP015345.1\|WP_057789657.1\|2055301_2057167_-\|short-chain-oxidoreductase	unknown	unknown	gnl\|CDD\|226715
NZ_CP015345.1\|WP_057789642.1\|2046114_2046903_-\|lipase	unknown	unknown	gnl\|CDD\|226200
NZ_CP015345.1\|WP_057789651.1\|2050891_2052223_-\|phosphopantetheine-binding-protein	unknown	unknown	gnl\|CDD\|181065
NZ_CP015345.1\|WP_057789626.1\|2025463_2026066_+\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl\|CDD\|131644
NZ_CP015345.1\|WP_057789653.1\|2052225_2053533_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236231
NZ_CP015345.1\|WP_057789663.1\|2059983_2061123_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015345.1\|WP_057789634.1\|2038630_2039104_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015345.1\|WP_057789636.1\|2039105_2039969_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015345.1\|WP_082604822.1\|2040004_2042104_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372604
NZ_CP015345.1\|WP_057789649.1\|2050052_2050895_-\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|224007

Protein	Function_ID	Function_description	E-value
NZ_CP015345.1\|WP_063456790.1\|2031140_2038610_+\|hypothetical-protein	gnl\|CDD\|293789	sd00042, LVIVD, LVIVD repeat. LVIVD repeats are mainly found in bacterial and archaeal cell surface proteins, many of them hypothetical. Structurally, LVIVD repeats have been predicted to form a beta-propeller, with each repeat forming one four-stranded anti-parallel beta-sheet blade.	1.29745e-30
NZ_CP015345.1\|WP_057789629.1\|2026167_2029836_+\|hypothetical-protein	gnl\|CDD\|372685	pfam13715, CarbopepD_reg_2, CarboxypepD_reg-like domain. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.	1.85747e-07
NZ_CP015345.1\|WP_057789646.1\|2048928_2050023_-\|DUF1624-domain-containing-protein	gnl\|CDD\|377915	pfam07786, DUF1624, Protein of unknown function (DUF1624). These sequences are found in hypothetical proteins of unknown function expressed by bacterial and archaeal species. The region in question is approximately 230 residues long.	1.33815e-05
NZ_CP015345.1\|WP_057789659.1\|2057253_2058627_-\|MATE-family-efflux-transporter	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	5.23445e-93
NZ_CP015345.1\|WP_057789640.1\|2042100_2045793_-\|hypothetical-protein	gnl\|CDD\|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	3.57988e-15
NZ_CP015345.1\|WP_057789661.1\|2058831_2059974_-\|HupE/UreJ-family-protein	gnl\|CDD\|379373	pfam13795, HupE_UreJ_2, HupE / UreJ protein. These proteins contain many conserved histidines that may be involved in nickel binding.	7.37693e-48
NZ_CP015345.1\|WP_082823971.1\|2053549_2054149_-\|hypothetical-protein	gnl\|CDD\|226715	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism].	2.80392e-26
NZ_CP015345.1\|WP_082823972.1\|2054124_2055432_-\|hypothetical-protein	gnl\|CDD\|377237	pfam04183, IucA_IucC, IucA / IucC family. IucA and IucC catalyze discrete steps in biosynthesis of the siderophore aerobactin from N epsilon-acetyl-N epsilon-hydroxylysine and citrate. This family represents the N-terminal region. The C-terminal region appears to be related to iron transporter proteins.	5.25744e-75
NZ_CP015345.1\|WP_057789644.1\|2047270_2048368_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.73446e-59
NZ_CP015345.1\|WP_057789657.1\|2055301_2057167_-\|short-chain-oxidoreductase	gnl\|CDD\|226715	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism].	5.31686e-75
NZ_CP015345.1\|WP_057789642.1\|2046114_2046903_-\|lipase	gnl\|CDD\|226200	COG3675, COG3675, Predicted lipase [Lipid metabolism].	3.08064e-47
NZ_CP015345.1\|WP_082604822.1\|2040004_2042104_-\|hypothetical-protein	gnl\|CDD\|372604	pfam13435, Cytochrome_C554, Cytochrome c554 and c-prime. This family is a tetra-haem cytochrome involved in the oxidation of ammonia. It is found in both phototrophic and denitrifying bacteria.	5.07192e-10
NZ_CP015345.1\|WP_057789626.1\|2025463_2026066_+\|PEP-CTERM-sorting-domain-containing-protein	gnl\|CDD\|131644	TIGR02595, conserved_hypothetical_protein, PEP-CTERM protein-sorting domain. This model describes a 25-residue domain that includes a near-invariant Pro-Glu-Pro (PEP) motif, a thirteen residue strongly hydrophobic sequence likely to span the membrane, and a five-residue strongly basic motif that often contains four Arg residues. In nearly every case, this motif is found within nine residues, and usually within five residues, of the extreme C-terminus of the protein. Proteins with this motif typically have signal sequences at the N-terminus. This region appears many times per genome or not at all, and co-occurs in genomes with a proposed protein-sorting integral membrane protein we designate exosortase (see TIGR02602). PEP-CTERM proteins frequently are poorly conserved, Ser/Thr-rich proteins and may become extensively modified proteinaceous constituents of extracellular material in bacterial biofilms. [Cell envelope, Surface structures].	0.00897608
NZ_CP015345.1\|WP_057789653.1\|2052225_2053533_-\|AMP-binding-protein	gnl\|CDD\|236231	PRK08308, PRK08308, acyl-CoA synthetase; Validated.	1.98263e-167
NZ_CP015345.1\|WP_057789651.1\|2050891_2052223_-\|phosphopantetheine-binding-protein	gnl\|CDD\|181065	PRK07639, PRK07639, petrobactin biosynthesis protein AsbD.	1.27925e-20
NZ_CP015345.1\|WP_057789649.1\|2050052_2050895_-\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	3.43895e-15

>NZ_CP015345.1|WP_057789644.1|2047270_2048368_+|Gfo/Idh/MocA-family-oxidoreductase
MSSVTRRHFIRMTGAGLLVAHSPLSLALGSTQSQKKLGVALLGLGNYSANLLAPALQHTEHCELRGIVTGTESKISQWQHEYGIQDSNVYTYDTMDEIANNKDIDVIYVVTPTGTHKDFAVKAANTGKHVWCEKPMAMDSDECQAIIDTCNKNGVTLSIGYRMQHEPNTRTFHHYLESMPYGKFKKVSSFAGYAGQGRDASNWRMQQHMGGGALYDMGVYAINSARFLTGKEPLSVTGSHPPQRFPNKFTEVDETTMFTMDFGDGLMADCGTSVVKEFNHFKAECQQGWYQLKPMQSYNGVTGTTSDGKKFEPIKGMQQTLQMDNDALAILTDRQPLVTGSEGLADIRIVNAIFRAAQTGKAVAV
>NZ_CP015345.1|WP_057789642.1|2046114_2046903_-|lipase
MKKLKRYQYERYAILCQLAYPDAEAHYRQILKPFYERHLVDKYGRMSVRILWVDNKKEAIVVFRGSLGFKDWLANLIFLPTKIRQIDKKFYVHWGFSRLLNQPMYSSTKTINEALPLQELLVKVLEPLQKQGKRFTFIGHSSGGAVAVLMADYFERKNAKAVKRVVTFGQPAVGSRSWYKNYLLHHKTYRICCDLDVVTFMPPFPFYFWHVGKMLWLHDDQIYENTPTHERFLKSLRSWLLRPITYHYMRKYIRNKSLFDEH
>NZ_CP015345.1|WP_057789640.1|2042100_2045793_-|hypothetical-protein
MRIPLKKNSRVYFFLLLSLLFSILVFGKMSRSYFSLVPLEITEKSNPKSTPTIVFKDKTLETGLLASHQQTTKVLTSIQQLIGGGICVLDVNNDGWQDLFIIGGSGEHRFYGRQTWWKNKVPQTNTLWLNNEGRTFENITVTSNLSTHLYPMGCSAGDLDNDGDEDLLVTNIGQNQIYENLGGGVFKDRTENSGLQDLKNWSTSASMADFDNDGLLDIYVTNFIDFQQGKKVFEQASGFVGSVNDSLNPILYESESNYLLKNKGHFQFNEVAVSQGVQDNSGRGVAARWFDINQDNYPDLLVVNSAGSPQRLFINQRPANQGFEESARHYNLSHSDGSHSIAIGDTNLDGYQDLLLSSPAGFPPKLYTHTRLEPFKSNSSISQQLYESSWESGIADNRLLYMFGWGAVLSDFNNDMFPDLFIGNGATSIDSDAPSLSIGQPNQLWVNKNGLFRSELLLSDNTAPTRGVINLDINNDGKMDIVTTQNNDYVSVLINESDLDAPWIDVELKHPKKLSNGAKVTLTFESQQSKTNQQIITSAFQPSSFLSQSTSRLHFALPPSVNMVDIEVLWPDNTITRYPSLEVNRIWQLKNAEEASILTNQTSDQTSEISTKTVSDKPWLSMLSEKQQSQLIQSIEGAILSSSNMQPDVNALMYRELDYLFTHVDSSLHTRNTIVQALTSASFTRDSLSLKFIERALVSSDDKIRIAGIKALMQQEHEISIRRLIRMDKDASPKVRCKIANTFKHFFHEEEAVVRRKGLANSHLIFMLSAKEESVKLCTIEALAEAENYRAVVPLIALATQPSSSEKVTIAAIRALGLIRDIKAVPELFRLLETESSARVKAATLIALKRLGYENFQSLIAQLLDFEHNGTQSINVAVALLHDNQLDSLVLKPDVIWQPLESTLNKLERLQLTIEDQILAALDLLILSDRNRKREILENYLTSDKSSIADKAATHLASISPSDEDTTKWRFADRTIKAQKHIIKKLIQRQHVFSKKELSDFLRNEETTQALLYSLKTYKYPKLLSLLKSIPIELINSENSRWLKLCDYQTKLTGTISLSWLENRPTSYQALNCWLKTDSNVASSPPLSFLKKLIPSAPLSTEMVSSRLTTVIEAIANHPTYEADRVLIELIKHHHILKVRKTALAIGLAFKKPYALDLAMHYAKAATRDVMTEFSQIQLTSAVPTDFQAQKFYDYLKIIAFSPAIPFDKRWAAMFKLIQDGQATLESFLL
>NZ_CP015345.1|WP_082604822.1|2040004_2042104_-|hypothetical-protein
MNNTTSTSQLLMREKRQNRWLYSMLVVLLLSGLYSYISSSHSVFSQWLVLAHGFIGTASLLLLVPFIINHFYRTLGQRRAGLFTSGIFLFVLSIVMGFTGVYIIVAGLTEQTAWLLNIHIASGFSLFGVLIFHVISHYIWLAPKRRASLARSKEQNFRYFPSLEEQAFLRIGTFALGFFTITFSLSLIYLAFEIEPSNQPAVTDYQYNYGPHPFRPSQTDTASGTFIDKNQIAGSQNCANCHKEIAEQWYSSIHKQAASDPTYVKNITLLSENKGIEATRYCEGCHAPVALLTGQLSEGGTHGGIKNTTAFHEGISCLSCHNIESATHLKGVASYRYEPHKPYLFDGYESNFFSALREYLIRINPSQHKTDMAKEILIEPELCATCHVQFMDKEMNNWGWVKMQDEYTAWLESPYSMQSEQVFAHSKKTRCQDCHMPLVKGNDPSANSEGEFRSHRFIGANTMLPSLNGDKEQLAQTQKFLQSNKVRLTINPPNRKDATQSDKQITEDIRAITETPAYFYLNETVKLNVVAANIGVGHNFPAGTLDINEAWIAFTALDATGKVIYQSGFLEDDLSVETNAYFYRSLPIDRFGKLVWKHDLFNRVGETYKNFIPAGGSDIVEYTFDVPSWAKGPITLNAVLKYRKLNQRYAKWALGEDYQDLPITDMARATILVPLRQQPPVRMESASSSFLNNTEIEAN
>NZ_CP015345.1|WP_057789636.1|2039105_2039969_+|hypothetical-protein
MKWRIIGMRVLFISSVAFTAVFSSNAQVLPIPNQNEHGAFLLDPWKPEAPVLVAFIDPYCPYCIKALKSKERYQYYNTFIFWAGILGDRSIARVEEILACNNPVSESVINSVVQRIAPECDTSKSLDHRELAQHMADAYDPMAVPSYYFGGRRVGLGELARMVNGVNQLESTVKLDWSRYAELRWRRNNHNLAKLIAVVPTEWSANEVQNNIPLDAKFDWYVAGANFEAICSQLNEGCELEAKEGYRKRSAEIQLLYDLKSSDKVQYVLNGVLLNDPTKLFSKSMVN
>NZ_CP015345.1|WP_057789634.1|2038630_2039104_+|hypothetical-protein
MNNHIKLYIVAIAICSVIAAFYFLNNNESTDLEINNEESQQRPSSGYKEQKSEKLSWFKNMLSDTSGSQTQSSVQAPLPPHLNSVKSNPNEVTIVVDESLIMQRELEFDTLIKDYNANLANRDNQKALKKRFKETSADYKQNIIAKVRQLNNNEGEN
>NZ_CP015345.1|WP_063456790.1|2031140_2038610_+|hypothetical-protein
MNKLNLVVLCIATVASSLPSYAVELNEKCVVNILNRTIQVDQDGYWALPNVPSNMGRIRARATCQLDDGRTVSGQSDYFAVVQNSVVQVGDIQFENVAPIPSDLNFSASTPISLDTIDQTFQLTITASYSDDSVQDVTSEISGINYGSTNPAIASVTANGLVTAHANGIALISARKDGVLVSRAVNISTSGDADGDGLPDDYETENGLNPADPVDAFEDKDGDGLTALEEYSAGTDINNADSDNDGISDKEELEAGEDGFITNPLLADSDGDGIRDGLEIFIGSDPNDENSGDLSNAVNFITVSPAAIFLTYNAIDGEASGQLRVTGHMLDGSEIDLTEQGSGTTYTSADLTIASFGLEDGEVFAGQEGTTEIIVSNNGSEFTVAVEVDEFEPVAVSAISIPGYANNVDVQGDIAYVAAGGSGLQIVNVADRTNPSIISAIDTSGTAIDVKVRGEYVYIADGSGGLIVVNVSDELAPTVVQEISTSGFAKDLSLHDDYIYIASDIGLEIFSIADPNNVIPVGENDALSKAKGVATDGDLLALINDNALAVFDITDRTAPLRITSSNIGNLKSIDFDNGYIYVAAYSTGWRSYKLNQPSASEPDAEVSLQQVAGNRDFVPRDVAVADGFTFFAEQLFPNVVAFVNTRDAENPFFQSTINLSSLGDYAGTGIAVDSAYAYITEERYIVSSDYKATGTTKLFIAQYRMLNDANGIAPEVNLLGPTDRSVVVAGSRINLSATANDDVAVRAVEFWVNGNKVAEDSTYPYQVPYTVVSDERVLTIVAKVFDYGSNSAESSPHLVEVQPDGDNDGLGDNEEVDVWHTDPNDADSDNDGVLDGEEIARGIDPNNVDSDSDGLNDGEELLNGTDPRNPDTEAPFVTATSPENGVTDQAENTPVEVVFNEPLLAKSVKSGALSILEDGLLEVPGSLRLTNGGTTLSFTASDLLKDYTNYTVVVAGVKDIAGNPIVEDYQFSFETGNTVDTDRPTVISVTPTANSTGVPVNASITVVLSERIDPLTIDENALYVVDRTTGLRIDGVTTLLDDNQSLTFAPNVAFLVGRQHQIVLTSQIKDLFGNTLYNTNYYFTTSFDTDATGPQIIATSVLDEQSDVPINARIRVRFDEAVNSLTLDNTKLLLNGNEVAVDTAISDNNTVVSLTPRLMLEPNTSYELFVDLVTDLSGNFLQQSKTIGFTTTSETDTASESITGTSPKSNDRETPLNAILDFSISGRLDPTTVTGNEVYLLDYDGTRARVSAEVSLSNDGQRISLIPSEPLLPGTRYRIYLGYGNYIYDLAGNRLSSNSYYFYTGTSMDTDAPEVVNHGLSGNVDEVALNSVINISFNEPLSEVCLSGDTVQLSNSSGAVAVSWSLSSDKQTLKVYAEDDLVANSDYQLTLNGLCDLAGQTLDNYQLNFTTGTARDTSGPSVIAITPSHGSTDVGVDSSIRVEFSEVLDPVSFVNRVASGHARVYAATGNVAGEWDVNGSVVVFTPTNPLPGATRVTTYLNDIEDQAGNDSSYRTYYFNTAATLDGVSPVVTSVVPADGAMDVGPNNDVVLTFSESLNSADINSYNFVVYNQGSLIRPTVYHSRDGRTVTLRSTWPSNAVLTVVVTGNVRDLSGNYLTDYASVFTTAVVDTDRSRPSVSRVYPSSGATNVPVDSSITLYTNEVMNESSLEEAIHVAQNGVLIGGTLTVTGSGRAIVFTPQEALTEGALIQVYLDSTATDDSGNALNSYESSFRVATPTATAGVRPVPIGYSPYSNQDDAPLNPTIQIAFNQAIDEGSLSGRVLLTKQSGGGEIAATVTVEQGSIVQIVPDTLLDAETDYYVRLDYRIEDMDGDQSGSWRYLYFSTGSDAVADDQQPQVVAMSPPDGTTDVALNPRIHVRFDEAINPIGVVPEAGMDMSFASNQRELLYTRHRPWLPASEITESVPSFTDIAGNAGVGASTSFTTGQEPDVAAPTVETYLPEYNATVPTNAVVRIRLNEAVDPLQVNTSNVYVVNTNDTSTRIPGQVSVESDGRTIVWTPNEVLAVNDRFYVRAYYMTDLSGNSTNHSHYFYTSSEADYVKPTVLSTSVTEGQTEVPLNARLRVRFSEPMSSLESELVFLTSLGESVPVNYSWNSDRTLLTLIPKQLMGINTTYTLNIGQSPDLSGNTVTPVTVSFTTGGFVDSIAGNIVTYSPSSNATDVPLNAVIEFKVSDELDPTLLTSGSFYVIDVDGDGLPILASLLLSEDGQTARLTPSDNFEANNRYRVYFGYGENLYDLAGNRLPYTSFYFYSGDAEDDVAIEVKNHNLSGSQNEVATNIQLRVTLSEKANPLCVTSSNVLLSDLDGLVPINVGLSSDQLTLLVTPTTNLKAVSNYALQLKNVCDLSLNKMADFQLAFTTGDSVDTSAPRIVSFTPEAYTTDVSLTTNISVEFDEPIDAERFLTEIRANDIRVYSSSDTISGNWTVVRNIATFDPLNPLPADTAIYVRVNDVDDQVGNESGVTTRYITTTSF
>NZ_CP015345.1|WP_057789630.1|2029852_2030986_+|hypothetical-protein
MYKLVSFLLLNMLLVGSALGDQRISFPVSIFKDSLPNPSSLYINFPYELVDKSYDQFRQGDLSQEDLIFLKTMDALRGNDAKSLFSLIKLESGLSNKEEIKSYILKFNNLYSGFSDLQIIAKITLYQRVLYVWSVNVRGRTIATSHIFEKINGTLKYKQLESASPLELVVKQAAVNSYYMPKKYPSLSNYKSQYEVELLNDESPSGAYMQFSGNLLTMSRNDEEYFKENNDSLLIFPFYQNMLSYIKTNSLNSFIDNLSPKSQKRIGGYPSPSESKEVSEYLKNLLLPIDLVFVLDADPFYLVFGTNDSRLLAEAAEKGNDSDILSRVNFSYAYLYKGKNGFEFVNVRYVNQFDMVLRKGNFIADSVLAPILSSNQK
>NZ_CP015345.1|WP_057789629.1|2026167_2029836_+|hypothetical-protein
MPGLKITEILHSLLFVLLMSLFCSFGANAEVLIDDLSLLSPEQVVVQYNGGRYDRRTGQMQYVATYTNVSGEELKGPFYLEIADISSTRVTVVNPSDTTSAGNAVFVSDTDTLEDGLTIEFSVIFSGRDRISYSSNAYNEKTIVLIDSDNDGVYDHEDECPNTPSGTLVAANGCMPLNTEPTVTIDSPVTLSTFGHSPVLVTGTVSEDVTTLTLNGIALTPASGQFEAQVALTEGHNVIVARTVDTNNNVETASITVSLDLTPPYVTLESHEDGDVVYTDKITVTGLVNDIVRGTVESTQANVKANGQVGEVSNRSYVVKDVPLEVGDNVIEVSASDQVGNTDKISFNIEYKLPIGKKIELNSGQDQSAPIGDLLSEPLSVKVSDDSGNPLANEAVIFRVTQGAGLVAYGDSNEGRAVVVDTDAEGIASTKFGIGARVGKANHKVSAKVVGFDGAVSFVASGLAKIGDKISVNSGNNQRGIIGQPLPSPFVVAVTDIGSNVVSGARVKFEVLVGGGVLQNGKGTYETTTDSDGRASAILTLGQLHGLDAQRVNVTLIDAPEGETLTAGFLASGFEAADPADTTISGVVLSNQDEPLEGVTVRVDGTTRESKTDGQGRFEIDSVPVGPVHLIADGSTVKGTGEYPALSYRIVTIAGVENPLSSPIYMVKLNLDNAVYAGKEDVSLTLEKFPGFKLDIAKDSVTFPDGSREGFVSVTPVNAAAVPMAPPNGMQPQFIVTIQPTGTQFYPPAKLTLPNVDGHSPGAQVEMYSFDHDLEEFVAIGLGTVTEDGSLVESNPGVGVVKAGWHCGSQPGGSGCCENKKKTCDYCSNKVGSCPGTCEFVPDRIAEVQTPGNCQKEYCGPSKEDNSDIPTNDVVGDCKKPGCEAGSATEIADPNDIKEEDKECKECSGLELTSKLDGTAVSGEICQECQGGAVKNKPNGTEIEGEVCKECSSGKVANVEDGVAPEASNLCKVCKGGKLINKVDPENFKPISDGPNLSLDLDRAKPLTSAIEAGLKKMGINASASLGASVSYKAGPCCNPSDGILVEEAVTEAKGNLSLDVKAEGRIPGLSRGFSEVGFDVGGFTGSVDFGIGVKASIALKFNGEFGQRYESCVNDGEDCAFGQLSVNFSPALSPFAEAIVCLAYDVFGVSIDGCAGVDGIISLTSGVSYSKSMNVGSCTIGSSGGGKIDDVAVTGEIKIILGSDDFGVSMGKVILLNGFDI
>NZ_CP015345.1|WP_057789626.1|2025463_2026066_+|PEP-CTERM-sorting-domain-containing-protein
MVKLVKKPVFSVLLVIASLNICSGAHAGLLSFNDFFADPSVSVAADGSEAIIREDIDFAVSTISLDPFLGDPDIIIPGLNVFLNFDFSFNEALNENDEFVYALFDSSTLEDLAFAAFTNSKTDSVSLDLSSLVGRTLGLYFGLNSLDSLLNSTANISNLSLITVTSPPPDSQVPEPSTLMASLAALMCFFVTRKRKVPMK
>NZ_CP015345.1|WP_057789646.1|2048928_2050023_-|DUF1624-domain-containing-protein
MTISASPSPQQGASLNHRLHTFDFARGILIVLMVLVHVLDFYGSTETHESFIGSSINLLASWQVAAWFVFIMGMFITYTPHQPLAAGLKRAFGLFALGYLLNLTRGTIPMWLSLKNGLVTQAQLGSYTPTTEFFIVDILQFAGIALACCLLVKHFLPHPKYWFLSAFLVTFASPFIWDVSTGWGYIDGVLKLFNGNKYQGAMFPLFPWLAYPLVGMIFGYRLRKSSNIYDFFQKSFWIGIAIIAVGLPITITDTDYHMASNMRPGPGMIISLTGGALVFLWLCQRLTQGQNANRFVSLLCFWGRNVTTYYVIQWLLVGWGLMLVGAQQLPPFAAMSAMIAVMALSHIGVVIWLKVHNIRAMKLA
>NZ_CP015345.1|WP_057789649.1|2050052_2050895_-|sugar-phosphate-isomerase/epimerase
MNLSICTISFRHQLISIEEIAQWAQANHFQGIELWGAHANNLADQPHYDKHWLATYGLKTTMLSDYLPLLVSENVLYHKVQHLCRLAKHWGASKIRTFAGGKGSLDYTDSQKVELFNRLQKICDWLAPHGLNLVIETHPKTYADSVTATQEMFACVDRNNLQLNFDVLHVWESGAEITHALDELLPHINHFHFKNISSESHLSVFAPENVYAAAGTREGMVPIFEGAVDYQDFIEYLHLHHSAGIANADTSLEWFGNHCKQVLSRDRYLIQRLQQTCLSA
>NZ_CP015345.1|WP_057789651.1|2050891_2052223_-|phosphopantetheine-binding-protein
MNKTTIIDAIKLILEKELNNQKLHHFTPSARLNEDLYLDSVQIMQLLVHIELTLGIDIPDAALNNDDVATVSSLADFLLTQSNTDTSKSSDATDDLSQAQEEFEDIKVHCFVSCLCESIKVNPNVDHRPFYFGVWDAEVLVNQDHHLAYHSDDINHDDFREWYKKLYGVTVTSWYCETLSKQENLHTLQTLLAQKSESENIMVMLDMYLLPERENKFNQNPFPHYVMLEETNDPETWFMHDPDFRWEGTQSKTQVIAAIESKAVAGGYIFDSRDITPTSNSVIAEYFLASFNDKNNPMTDKVREIVDAHIDTNNSSTDITQLGEALKQLPVLAIRKYAYEHGFAFFWRDIGFPEAEFEHWCDVIEALVSNYKNIQFRAMKLATEQLSLANKNVLITEIYSLIDQQDEREFRIKQHLFNVFSQWSALHKLDLHGSQTITEEATA
>NZ_CP015345.1|WP_057789653.1|2052225_2053533_-|AMP-binding-protein
MLSVDTTFYSTYDFERFYQQFSTISVLHDKHVNIAVCLRDTATWLALCLYAKNHDISVLPIHPDTPLELAKRNACRAKCGVLFFGDMHNQITVDYRGETDGIAGLIQMSSGTTGEPKCIKRSWVAIDIEIASYISHFQDADDMTPYVACPVTHSYGLICGVLVALGRGKSPTIITNINPKFIMKMVMAAKKPLLYSSPAMLNMISLLWPKTNSLYAAMTSGTLMSKPTLEKVGKRVTHLYQQYGCSESGCVSLSRIESSNTSIGEVLPHVQISSGQDANHPEEIVITVPAINTCHQPQIIYTQDLGYFEHVENASPVLHFVARQDDTIIVSGLNVYPQEIEDIVLEHPSVIDAVLFKVNDTTAGQRACLYFTTDQLDADALRMWCRDKLAAYQIPQYLHAVEHIERLANGKVNRKKLAENYANQKPQSALEQVAG
>NZ_CP015345.1|WP_082823971.1|2053549_2054149_-|hypothetical-protein
MPFIDPWINKYGCEAWLTQLIEATIIPVWHLLVKHGIAVEAHAQNMILRHQHGWPTSVVLRDFHESVEYVEDYLAQPKLKPHFAELHHDYVHAPDNQYYWMSQVDALRELLVDTLFVYNLTDVATLMQRFYHYEETQFWQQVTNTLSAYEKNSPSWRSRIHKIDLLAPKIQTESLLAKKLSGQGAQEFHHTIPNPLHPL
>NZ_CP015345.1|WP_082823972.1|2054124_2055432_-|hypothetical-protein
MNCRLRWNKPFIPKLKILSIAKPLKFLYPVPQQPPSRPALNQLNVETSTKLAHRQHGLNSAAKSRVIKQLVEALLFEQLVPYHYTNGNFWFSVGDTRYIARGHISSFGRIRLDATYIKQIAPFKTATIDLPTLINALPASDATKDQLLKELSQTIGFSEWNDAHLTPIKSRRDLNYSALESAILEGHPYHPCFKARTGFSLSDHASYSPEAGSEFKLHWLAIKRQFLAANLPTEEDCFWQQELGESTLTTLRQRLQVLTPDSQEYGLLPIHPWQRNKLSTALSQPINNKEIIDLGECGDSYQATISVRTLLNITSPQKAHVKLPMNMVNTSSLRTIEPHSVTTAPVISNWLDTLIKQDSWYQKRQNFAIQHEYAGIVVRHPNVAAGSEHWANKLSPSLSVIFRNSQPLQGAIQTPFPLLHYHLLNKTACPLSIHG
>NZ_CP015345.1|WP_057789657.1|2055301_2057167_-|short-chain-oxidoreductase
MATIAKQIADNASYQAFVNGYLKEIDEGVWHSIAQWNLASGFDTGNHDKFMLELQLQHSEIKLVFGVAFRSIVGRHKLTGIYHQRLNSMEWRQLDSISAIMLLIKEIYARSNSHHVCDQELELTSRTIESHQIMADYIQERKDDPALQSPRFIDSEQSVLFGHWLHPTPKSRQGMHRWQHAHYAPELKGCFKLHFFAVERQWLNQSSAIALCAEQIVLRIAEQGACDTELALVKQFSESGKALVAVHPLQAEWLLKQDYIQQLISTGQLHPIGPLGATFTPTSSVRTLYCEQLNFMVKVSIPVKITNSMRINMGHELDAGVTLAKLLNTTRFSSLHPQFQVIGDPAYLSLSLPDRDESGFEMILRDNPFKQTKNELGIGGIQSIAALVQDAILPNERSKLSTIVHTLSEQQGRSLHQTSIAWFDRYWQCAIEPAIRLFDQFGIALEAHQQNSLLDLTEGYPKTYFYRDNQGFYLSSSVKSTLMQLEPDLIKCPELFYDNNMIFDRFGYYLVINQLFSVINRLGLDGLVSEETLLNLARIKLDKLLTQVSPLGQGLIRSITERKSIPCKGNLLTRVDDVDELQAEMEQAVYTQIKNPFYRKAPQVSVSSTATTTLEACLESA
>NZ_CP015345.1|WP_057789659.1|2057253_2058627_-|MATE-family-efflux-transporter
MSSREQNRVLAGPPIITFFYYVIPSMIGLLSLTTASLVDGIFVGNIVGSDALAAVSLLLPYLTFLIAISLMLAIGGAVTAGKYLGEGNTTAASDIMSKTLITAVLVNLFFALLSLALEPTLYAILNVPAHIQPLVTEYFAIIRWVFILQLSTMVLYYFVRTDGHPVLGTKALVIGALTNVVLDWVFILHLDMGIAGAAYATAIAQLIQCMVLVTYFFSPKRTLRFSFKQQNWRAIVSTAYNGVSEFVNEVSVGALFLLLNWLLIAQLGANGVAAFSVVNYFIFLSVMVSYGVADALHLLVSQNYGAKNTPRVYAFLKISLSSVLLTGLLLAGALIFAQTSLTTLFLNERDSEVTELVGDVIGLMWPVFIVNGINILLGCYLTAIHKPAPSALIALCRSILFPATMLVFLYLVFYHTTLLSLSPSPLLFLIALPIAEWLTFVFALIYSYRFRPSTLLE
>NZ_CP015345.1|WP_057789661.1|2058831_2059974_-|HupE/UreJ-family-protein
MKALVVTLFLSLLVMNASVVNAHELSSGYLTLSAGEENTYSGELLLKPDDIGQVAGLDTNGNGALTWGEIHQNQPLLQSYIAKVLSIKVDDTPCKISLSMPNIRSVSGDSYLVSPIQVMCESAGTLGIHYDGIFEHSPTHKLLVNVNLAGQSGVSSQSSTEKTSVTSVLDFDNRSVTYDAVTTSLTALFISLVYEGVWHIFIGIDHILFLVATLLTVNLAREKKQWQKEPSASRVVKHTVILVSAFTLAHSITLTATALNFIALDSRLVELGIAISVLLTALNNIYPLIVRLGIITFAFGLLHGMGFASVFADLNAQSNNLVLSVAAFNIGVEVGQLAIVAVLLPLLLWLRHYTFYAKTLMPLLSSVIAIIAINWTIQRW
>NZ_CP015345.1|WP_057789663.1|2059983_2061123_-|hypothetical-protein
MKKLVSRFLALSTLTLLNISAFSASSTEYSSDTVIATWSAKSETEMTLSQAKKLLNESRYPDATGNERQQVTHFIHYQKQKKDTLSATALTELMVLEAKVLQGTHQFSQAAAILNTIDTTNNAAALLLLADINIQQGNPAAAKTHCQQLVGKTSYLLAFTCMLNAEFTLNTSTATYEKLLSLEGFADKAHAEEVSDSERLWYYETLAAMAYSLDKPEATISHLDKLSAQKLPVSALLLWSDAQLKLAQPQRIIDRFKAMQSASNSTSKRTFSLTSNDSGNNAGNSIDDGLLLRWAKAERQISLHGTEIQKQLADRMALRTWREDVSHAAQVASYFLDIDYKPAIALKFARLNWQAAQTRSDARLLARAESAVATSSTLN

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Crispr_ID: NZ_CP015345_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015345_2

4249119-4249436

Orphan

Consensus_repeat	Method
CTGGTTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTAAAATTCA	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP015345_2

>merge|NZ_CP015345|2|4249119-4249436|PILER-CR
CTGGTTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTTAAAATTTTTTATAAACACGACACGACAATCCCTGGTTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTAAAATTCATTATAAACACGACACGGCAATCACTGGTTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTAAAATTCATTATAAACACGACACGGCAATCACTGGTTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTAAAATTCA

>NZ_CP015345|2|1|4249119-4249436|PILER-CR
CTGGTTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTTAAAATTT	TTTATAAACACGACACGACAATCCCTGG
TTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTAAAATTCATTAT	AAACACGACACGGCAATCACTGG
TTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTAAAATTCATTAT	AAACACGACACGGCAATCACTGG
TTCAACAACTTCGTTGCGAGCCTCAGTAGCGTCCACCACTTCCTTTTTTTAAAATTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015345.1\|WP_057792830.1\|4244108_4244339_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015345.1\|WP_057792833.1\|4249687_4251313_+\|response-regulator	unknown	unknown	gnl\|CDD\|381123
NZ_CP015345.1\|WP_082604944.1\|4243935_4244109_-\|DUF1289-domain-containing-protein	unknown	unknown	gnl\|CDD\|377738
NZ_CP015345.1\|WP_057792841.1\|4255034_4255250_+\|DUF3820-family-protein	unknown	unknown	gnl\|CDD\|378970
NZ_CP015345.1\|WP_057796252.1\|4244406_4245309_-\|M14-family-metallocarboxypeptidase	unknown	unknown	gnl\|CDD\|349450
NZ_CP015345.1\|WP_057796250.1\|4241681_4242662_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015345.1\|WP_061997536.1\|4257117_4257891_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|235150
NZ_CP015345.1\|WP_057792846.1\|4255674_4257018_-\|3-deoxy-7-phosphoheptulonate-synthase-class-II	unknown	unknown	gnl\|CDD\|366662
NZ_CP015345.1\|WP_057792824.1\|4240691_4241348_+\|arylesterase	unknown	unknown	gnl\|CDD\|238860
NZ_CP015345.1\|WP_057792839.1\|4253176_4254970_+\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|227590
NZ_CP015345.1\|WP_057792842.1\|4255252_4255576_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015345.1\|WP_057792837.1\|4251908_4252877_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_CP015345.1\|WP_057792827.1\|4242725_4243664_-\|tRNA-dihydrouridine(16)-synthase-DusC	unknown	unknown	gnl\|CDD\|236713
NZ_CP015345.1\|WP_057792852.1\|4258889_4259357_-\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP015345.1\|WP_057792831.1\|4246921_4248331_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NZ_CP015345.1\|WP_057792821.1\|4239975_4240674_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226647
NZ_CP015345.1\|WP_057792819.1\|4237437_4239960_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|225669
NZ_CP015345.1\|WP_138118059.1\|4257887_4258826_-\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl\|CDD\|235159
NZ_CP015345.1\|WP_057792835.1\|4251300_4251828_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP015345.1\|WP_057792825.1\|4241415_4241601_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP015345.1\|WP_057792833.1\|4249687_4251313_+\|response-regulator	gnl\|CDD\|381123	cd17589, REC_TPR, phosphoacceptor receiver (REC) domain of uncharacterized tetratricopeptide repeat (TPR)-containing response regulators. Response regulators share the common phosphoacceptor REC domain and different output domains. This subfamily contains uncharacterized response regulators with TPR repeats as the effector or output domain, which might contain between 3 to 16 TPR repeats (each about 34 amino acids). TPR-containing proteins occur in all domains of life and the abundance of TPR-containing proteins in a bacterial proteome is not indicative of virulence. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. Some members in this subfamily may contain inactive REC domains lacking canonical metal-binding and active site residues.	8.6048e-32
NZ_CP015345.1\|WP_082604944.1\|4243935_4244109_-\|DUF1289-domain-containing-protein	gnl\|CDD\|377738	pfam06945, DUF1289, Protein of unknown function (DUF1289). This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	3.74094e-17
NZ_CP015345.1\|WP_057792841.1\|4255034_4255250_+\|DUF3820-family-protein	gnl\|CDD\|378970	pfam12843, QSregVF_b, Putative quorum-sensing-regulated virulence factor. QSregVF_b is a family of short Pseudomonas proteins that are potential virulence factors. The structure of UniProtKB:Q9HY15 a secreted protein has been solved and deposited as Structure 3npd, from pfam13652. It is predicted that these two adjacent proteins form a single transcriptional unit based on the prediction that together they interact with their adjacent protein PotD, which is the putrescine-binding periplasmic protein in the polyamine uptake system comprising PotABCD. These two adjacent proteins are predicted to be quroum-sensing-regulated virulence factors.	1.47048e-36
NZ_CP015345.1\|WP_057796252.1\|4244406_4245309_-\|M14-family-metallocarboxypeptidase	gnl\|CDD\|349450	cd06231, M14_REP34-like, Peptidase M14-like domain similar to rapid encystment phenotype 34 (REP34). This family includes Francisella tularensis protein rapid encystment phenotype 34 (REP34) which is a zinc-containing monomeric protein demonstrating carboxypeptidase B-like activity. REP34 possesses a novel topology with its substrate binding pocket deviating from the canonical M14 peptidases with a possible catalytic role for a conserved tyrosine and distinct S1' recognition site. Thus, REP34, identified as an active carboxypeptidase and a potential key F. tularensis effector protein, may help elucidate a mechanistic understanding of F. tularensis infection of phagocytic cells. A functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	2.35131e-59
NZ_CP015345.1\|WP_061997536.1\|4257117_4257891_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|235150	PRK03695, PRK03695, vitamin B12-transporter ATPase; Provisional.	2.31876e-58
NZ_CP015345.1\|WP_057792846.1\|4255674_4257018_-\|3-deoxy-7-phosphoheptulonate-synthase-class-II	gnl\|CDD\|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NZ_CP015345.1\|WP_057792824.1\|4240691_4241348_+\|arylesterase	gnl\|CDD\|238860	cd01822, Lysophospholipase_L1_like, Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity.	2.81271e-90
NZ_CP015345.1\|WP_057792839.1\|4253176_4254970_+\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|227590	COG5265, ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP015345.1\|WP_057792835.1\|4251300_4251828_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	5.06473e-24
NZ_CP015345.1\|WP_057792827.1\|4242725_4243664_-\|tRNA-dihydrouridine(16)-synthase-DusC	gnl\|CDD\|236713	PRK10550, PRK10550, tRNA dihydrouridine(16) synthase DusC.	2.46523e-140
NZ_CP015345.1\|WP_057792852.1\|4258889_4259357_-\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	2.34476e-75
NZ_CP015345.1\|WP_057792831.1\|4246921_4248331_-\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP015345.1\|WP_057792821.1\|4239975_4240674_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226647	COG4181, COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism].	1.74635e-110
NZ_CP015345.1\|WP_057792819.1\|4237437_4239960_-\|FtsX-like-permease-family-protein	gnl\|CDD\|225669	COG3127, COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP015345.1\|WP_138118059.1\|4257887_4258826_-\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl\|CDD\|235159	PRK03784, PRK03784, vtamin B12-transporter permease; Provisional.	5.88821e-60
NZ_CP015345.1\|WP_057792837.1\|4251908_4252877_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	6.26405e-163

>NZ_CP015345.1|WP_057792831.1|4246921_4248331_-|glutamate--tRNA-ligase
MSVVTRFAPSPTGYLHVGGARTALYSWLLAKNNGGEFVLRIEDTDIERSTEEAKQAILDGMQWLGLTWDTGPIYQTDRFDRYKDLIQQLLDEGKAYKCFMSAEELDAIREAQKERGEKPRYPGTWRDRTDHPEGEPFVIRFKTPLEGTVVITDHVRGKIEINNSELDDLIIQRTDGTPTYNFCVVVDDWDMGITHVVRGEDHINNTPRQINILQALGAPVPEYAHVSMILGDDGKKLSKRHGAVSVMQYRDDGFLPQAVLNYLVRLGWSHGDQEIFTLDEMIELFSLDAIGQSASAFNTEKLIWLNQHYIKSLPASEVAGHLKWHFDGLEVDLTTGPALESVIAIQADRVKTLKELAEISTYFYQDYEDFDANAAKKHLRPVARGPLELVKEKLMAIEAWEPENIQAAINTTAEELEVGMGKVGMPLRVATTGSGNSPSLDVTLNLLSKEKVGERIDKALTFIANRENS
>NZ_CP015345.1|WP_057796252.1|4244406_4245309_-|M14-family-metallocarboxypeptidase
MQNYPIGTPGQPWGEEEKEEWKQRQTIKRSYSDEVLKQLGSIPEGFELKQYGALPYDESRYPLYAVIPKNIDAAKPAVLVTGGVHGYETSGVQGALQFINTKLSEYAEDFTIIVVPCVSPWGYETINRWDQYALDPNRSFYPNSPAPESAQLMAFVESLNLPFTLHVDLHETTDTDNSEFRPALAARDATTHDNWNIPDGFYLVANTTNPQKPFQEAIIDAVKQVTHIALADDSGKIIGADLLSEGVICYDKKALYLCGGMTDAEFVTTTEVYPDSANATAENCNAAQVAVITAALEYIK
>NZ_CP015345.1|WP_057792830.1|4244108_4244339_-|hypothetical-protein
MFTFSALIYDGYKQQLVKGDYEDKTQFDAFLNAKFGVHVCMWTAKEPTQKVIDAMLHASLIAKNTASENQTLRAKY
>NZ_CP015345.1|WP_082604944.1|4243935_4244109_-|DUF1289-domain-containing-protein
MSIVSPCIANCKLDADDVCTGCKRTIKEITSWSSYSTQQKQNVLIRLQTQKLDTHSS
>NZ_CP015345.1|WP_057792827.1|4242725_4243664_-|tRNA-dihydrouridine(16)-synthase-DusC
MKIMLAPMEGVVDHLMRDMLTHVGGFDQCVTEFVRVVDQKLPNKTFYKLCPELHNGGKTPNGVPVRVQLLGQHPEWLAENAYTAVDLGSPGVDLNFGCPAKTVNKSKGGAVLLKETQALYDIVKAVRDAVPASQPVSAKIRLGFEDKSLAVENAIAITEAGASELVVHARTKTEGYKPPAYWEWIAKIKQSTNIPLVANGEIWNAEEAQRCQEQSACTNLMVGRGALAMPNLARCIRNDEPPMAWEDVAALLIRYSGYEIYGDKGKYYPNRIKQWCGYLKRQYPEAELLFNDIRRLSKSQEIVDVLARQASH
>NZ_CP015345.1|WP_057796250.1|4241681_4242662_+|hypothetical-protein
MPLPRYKQVNLDVTPYYHCTSRCVRQSFLCGVDASTGKNYNHRRQWIVDRLHKLTKTFAIDLCAYAVMHNHTHIVVHIAKARAEHWSMDEVLLRWKNFYRCPSVVQRYLDEETRSSLSEVELQKAEELSEIYRHRLYSVSWFMRLLNEFIARKANKEDECSGYFWERRFKSQAILSENALAATMAYTDLNPIRADIAKTPEQSHFTSIQYRINALKVNKVPARLMPFNDQVPVNESSLPFNLTDYLVLVDETGRVMRSDKKGAIPKKIKPILDRLKVSGKSWITLSTKLERKFAGPIGSAERICVYASACEYGRKPNIANARRYLQ
>NZ_CP015345.1|WP_057792825.1|4241415_4241601_+|hypothetical-protein
MDVSSSTSTPVSNVLQSPQQEPQRQVQQRASQQTEVSAPQQTQEAAPATDSRVGSRIDTYV
>NZ_CP015345.1|WP_057792824.1|4240691_4241348_+|arylesterase
MIYRFRSAVLFTLLLFIPLSALSDQTDTTVPNNSAKLLILGDSLSAAYGLDQQEGWVSLLQKRWRDENISIDIVNAAVSGETTDGGLARLPRLIEQHTPSHILVELGGNDGLQGHSISKIRDNLSAIVRIAKSDNTVVFVQDMQIPTNYGKRYTQMFSDTFETVSEQHEVTKIPFFLEDIALQKDLMQRDGIHPNAEAQPMIVDFMFEKLTPLIINKR
>NZ_CP015345.1|WP_057792821.1|4239975_4240674_-|ABC-transporter-ATP-binding-protein
MIKTSKVTKSVTTSEGTLEILHPISFEVKSGESVAIIGASGSGKSTLLGLLAGLDEVSQGEIHLDGEPLHTMDEEARAVLRGQKVGFIFQSFMLVQSLTAIENVMLPAEIAGLDNPKQMATKILEQVGIGHRASHYPNQLSGGEQQRVAIARAFITSPKILFADEPTGNLDATNSHKVEDLLFALNREKGTTLVLVTHDNKLADKCDRQLTMQAGELTESTVLSAIKRTEAV
>NZ_CP015345.1|WP_057792819.1|4237437_4239960_-|FtsX-like-permease-family-protein
MSTTSTLAWRLFRHEAKRGELTIILLAIVLSVGAVLSLSLFSERLQGALKERSAAFIAADAQLRSDTPIDEAWLQHARDGGLNTAKQVTTRSMVFHRDEMSLVDLRAVNENYPLKGTVNTTDVPFGQKEAARDLPKPGEVWLQSLLFQTLKLSLGDSIEIGDAEFTVTKVLVDIPDAGFSVFNTDPIALIRLSDLDATAITGPGSRARYVGYFEGESSAISTFYDWLTPSLNDDLHNWRTVEDDESAIGRSVASAERYFLLASLLAIVLAAVSIAVAAQRYSQRHFDPVAIMKTLGATKQVIRRIYLLQILFITGLGIIIGLIMGFIGQQIVVWLVAEQVDVALTIWHWRPVLIAVFTGATCSLLFSLYPLMQLFSIPPLRVLRRDLSTNLRSRTIQYVASGGAIFLLMWIYSQDLMISLILFGSGVVLVAGLLGATFLLIAAGRKFGSGKMGPWQLAWARIKRRSMENSVQLISFSVTIMLLLVVLVMRNDMVSQWRSQLPEGTPNYFLINITGDQKTELDTHFKSNGITIEEFYPVIRGRFVAVNDDSVNTEVSKEDDSNTEGRQGLGREANLTWSNSLQKENEIISGTWHGDNTDALEEDVFAVSVETDVGERLGIELGDMLTFNVGSEIVITKVTSFRKVNWQTMQPNFFFVIQPEAMASFNPTYITSFYLPEAQKSQLTTLLKPFASITMFDVDARINQLRDIVNQVSVAIEFILVLVLVAGSLVLIAQVQASMDERRQELAILRTLGAKGSLIRKSVVFEFLIIGVVAGFMAALANELSLYMLQTNVFQMTASLHFEYWVIAPIVGAIVVGALGAIGCWRLLTLNTSALLRKMV
>NZ_CP015345.1|WP_057792833.1|4249687_4251313_+|response-regulator
MNLQLARQTRLLIAEDQALAKSHMKYALEQLGFQHIDYVDRAAYALTSLRTRQYDVIVCAYDLRQEQGGYNLFEQLKTEKIIPLTTGFIFTSADTAIDVVHAIIELQPDEFLAKPFSVNELDKRLSKVVTRKKVFHDVYRYMDDQNPEQALKELEFILVEPKNAEHFPLALKTKGDLLLLNRQFENAKLFYQSIINIQNFTWAKLGLVQCYIHLDEFDDAERDLIQLALQPESMLSAYDLLAELQIKLEAYDEALECVNVASDISPRNVMRHITAVQLARLTHDYEGQFNSAKKVVRFGKNSVHDTPEMYLSVARAGIDFAMTAETSQTNKIIKQSNEYLRQLKSAYPKVNLDHQLQVISARIHYLKDENDKAKDLLDALDIDNLEEQSVETLLDSAKAFHDLGLRGSALKLLDKATLRQKELDAPNSLLSRYINQEVVEKTAISISPKNLNDVAVVQYKRGELAKSYQTFEQAFRVMPHNAAIALNLLQASAMRRSREGKAEASMNSVMKKCRFTLESASLSEEQSQRYETVKGLLDQVV
>NZ_CP015345.1|WP_057792835.1|4251300_4251828_-|GNAT-family-N-acetyltransferase
MFIEDSARLSFHYITDSDTEFLWELDQDEEVMRFISDGQKTSREDVTNTFVPRFQAYSNPALGWGLWRVQEKESEEDIGWILVRPFGFFTKDPEIDNIELGWRFKQASWGKGYATEAAMQVKDALYQIGIDKFCAMAKQENLNSIKVMEKIGMSYSHEIEYKDNLYQEKVVVYTT
>NZ_CP015345.1|WP_057792837.1|4251908_4252877_-|GTP-3',8-cyclase-MoaA
MLEDSFGRQFHYLRLSVTEACNFRCQYCLPDGYQGPSSEHFLSLGEINTLLSAFSGLGTSKVRLTGGEPTLRRDFLDILSATANTPGIKRVAMTTHGGRMAEHAASWKQAGLHQVNVSIDSLDPRQFAAITGQDKLKQVLAGLDAAVEAGLDVKVNSVLLNDFSDARLNRFLEWLKTMPVTLRFIELMETGDTTSFFKAQHQGGTPLKQTLIDAGWQPMVRRKDAGPAQEFFHPDYAGKIGLIMPYSKDFCKSCNRLRVAANGKLHLCLFSEHGIDMRHLLAEQDVVGLQQFLVECLGEKHATHFLHEGNTGATKHLAMLGG
>NZ_CP015345.1|WP_057792839.1|4253176_4254970_+|ABC-transporter-ATP-binding-protein/permease
MRKNRFPLNENEPIKWQVLKQLWPYLLEFKGRVALALMCLVAAKLASIGLPYVLKYTVDSLNGDVQALAIAVPISLIIAYGALRLTNVLLGEVRDTLFGRVTERAMRRLGLKVFNHLHNLDLGFHLNRRTGGLSRDIERGTNGVSFLMRFMVFNIVPTLLEIGLVVILLLIQFGWSFAMIIVVSVISYVLFSMKATDWRTRFVQQMNEADSTTNSRAVDSLLNFETVKYFNNERFEASRYDTDLAGWEKARRKNRLSLFALNGGQASIIALAMTAMMANAAYGVMEGEMTIGDFVLINAFTMQIFMPLNFLGFVYREIRGSLANIQNLFSLLAQKPAIEDKPNAAHLSANQASIRFSNVQFHYQQARPILKGISFDVPSGAKVAVVGESGAGKSTIMKLLFRFYEPSEGGIFINGQDIRDLSQHSLRSHIGIVPQDTVLFNTSLVENIRYGNPDASDDEVNHAIKLAHLTQFVESLPDGLDTTVGERGLKLSGGEKQRVAIARALLKGAPIMIFDEATSSLDSQSEQAILGALRDAAKGHTSLVIAHRLSTIVDADSILVLSKGMIAEHGTHETLLAQQGIYNRLWATQQRESNDEA
>NZ_CP015345.1|WP_057792841.1|4255034_4255250_+|DUF3820-family-protein
MDPEAIKSAINQTMPFGKYAGRRLFHLPEPYLVWFNTQGFPEGKLGQQLALMYEIKLNGLESVVEPLLHDD
>NZ_CP015345.1|WP_057792842.1|4255252_4255576_+|hypothetical-protein
MFARPRKQKREAIDQRILRLHTGIAKKIIAQPSLINDVQATLEARYESGMMRYGSYILWQGIVETLHTPEVFTALLLAEDVRTASLRRETIFTGILTEAERAEILED
>NZ_CP015345.1|WP_057792846.1|4255674_4257018_-|3-deoxy-7-phosphoheptulonate-synthase-class-II
MSNWQVDSWRQKPILQQPEYDDAAQLKQVEHTLSTYPPLVFAAEARDLRRQLGEVSLGKGFLLQGGDCAESFDEFNAPKIRDTFKVLLQMAIVLTFAGRCPVTKVARMAGQYAKPRSSNFETRNGVTLPSYRGDIINSFEFNEAARRPDPNRLIEAYHRSASTLNLLRAFSQGGLADLHEVNRWNMAFVENNPLKERYHDMAVRIQDTLSFMDVIGINSQSSPTLHETSLFTSHEALLLNYEQALTRIDTLTGKPYDCSAHMIWIGERTRQLDHAHIEFFRGIHNPIGVKVGPSMEEDELIRLIDALNPNNDPGRLTLITRMGADNLADNLPRLLRRVKAEGRHVVWSSDPMHGNTFSASSGYKTRNFDAILREIKQFFQAHNDEGTHAGGIHLEMTGQHVTECTGGAYEISDEDLAQAYKTQCDPRLNADQVLEMAFLVADHLRNA
>NZ_CP015345.1|WP_061997536.1|4257117_4257891_-|ATP-binding-cassette-domain-containing-protein
MSSVITLRDISVNKRLANITLDINKGDCVHILGPNGAGKSTLLSIMAGVLETEHGEASLLEQSLQQWPLSALAAFRTLLAQQSEAVFAVSVKEYLSFFSSEPTFELPSLLEATLEVTGFLQTPLNRLSGGERQRVEICRALLQVWPAIKRGEALLLLDEPLQGVDIRHQYALMALFQTLCTKGNTLVLSSHDISLSANYSYKVLLMKLGTSVSFGLTESVLSVKNLEQTFDCHFAVNKRDDFLDIQVCAPIVLDQMW
>NZ_CP015345.1|WP_138118059.1|4257887_4258826_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MFLLCSITFLLIVGVLATVWLTDSPTALKQHITLQLQIPLIITAILVGSVLAVSGATLQIVLRNPLADPGIIGITSGASLVAATLLLLTPLWAQPYLHYILPLGCFIGALITTFIIYRLARKLLGSAVAVILSGIAISTLSGAVIAWLYMFSDAQSLRNLTFWLMGSVYQTTWPILWVSGPLIIGSLWYQMGQSAKFNRLYAGDLAALSSGVHVQQLTERSLIATAVGVGAAVSIAGAIAFVGLLVPHILRLILGHDNRLLLPASALCGASLLLIVVLMSELTRAITLPVSMITATLGGPLLIWALLKGQLR
>NZ_CP015345.1|WP_057792852.1|4258889_4259357_-|low-molecular-weight-phosphotyrosine-protein-phosphatase
MGQNTSVLFVCLGNICRSPTAEAVFIRKAADAGLKLDIDSAGTHGYHIGKQPDKRSQAVGVERGYSFKGLKCRRVDDKDFEKYDYILAMDNSNLDNLREMSAPEHHEKIHLFLDFANSEDKEVPDPYYGGKRGFELVLDLIEEASDGLIAHIQQS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP015345_2	2.2\|4249271\|23\|NZ_CP015345\|PILER-CR	4249271-4249293	23	NZ_CP015345.1	4249096-4249118	0	1.0
NZ_CP015345_2	2.2\|4249271\|23\|NZ_CP015345\|PILER-CR	4249271-4249293	23	NZ_CP015345.1	4249437-4249459	0	1.0
NZ_CP015345_2	2.3\|4249356\|23\|NZ_CP015345\|PILER-CR	4249356-4249378	23	NZ_CP015345.1	4249096-4249118	0	1.0
NZ_CP015345_2	2.3\|4249356\|23\|NZ_CP015345\|PILER-CR	4249356-4249378	23	NZ_CP015345.1	4249437-4249459	0	1.0
NZ_CP015345_2	2.2\|4249271\|23\|NZ_CP015345\|PILER-CR	4249271-4249293	23	NZ_CP015345.1	4249012-4249034	2	0.913
NZ_CP015345_2	2.3\|4249356\|23\|NZ_CP015345\|PILER-CR	4249356-4249378	23	NZ_CP015345.1	4249012-4249034	2	0.913

1. spacer 2.2|4249271|23|NZ_CP015345|PILER-CR matches to position: 4249096-4249118, mismatch: 0, identity: 1.0

ttataaacacgacacggcaatca	CRISPR spacer
ttataaacacgacacggcaatca	Protospacer
***********************

2. spacer 2.2|4249271|23|NZ_CP015345|PILER-CR matches to position: 4249437-4249459, mismatch: 0, identity: 1.0

ttataaacacgacacggcaatca	CRISPR spacer
ttataaacacgacacggcaatca	Protospacer
***********************

3. spacer 2.3|4249356|23|NZ_CP015345|PILER-CR matches to position: 4249096-4249118, mismatch: 0, identity: 1.0

ttataaacacgacacggcaatca	CRISPR spacer
ttataaacacgacacggcaatca	Protospacer
***********************

4. spacer 2.3|4249356|23|NZ_CP015345|PILER-CR matches to position: 4249437-4249459, mismatch: 0, identity: 1.0

ttataaacacgacacggcaatca	CRISPR spacer
ttataaacacgacacggcaatca	Protospacer
***********************

5. spacer 2.2|4249271|23|NZ_CP015345|PILER-CR matches to position: 4249012-4249034, mismatch: 2, identity: 0.913

ttataaacacgacacggcaatca	CRISPR spacer
ttataaacacgacacgacaacca	Protospacer
****************.***.**

6. spacer 2.3|4249356|23|NZ_CP015345|PILER-CR matches to position: 4249012-4249034, mismatch: 2, identity: 0.913

ttataaacacgacacggcaatca	CRISPR spacer
ttataaacacgacacgacaacca	Protospacer
****************.***.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

11726 : 20638

Staphylococcus_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057793518.1\|11726_12533_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-25	32.1
WP_057793520.1\|12754_13795_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	1.4e-119	64.1
WP_057793522.1\|14049_14538_-	CinA family protein	B5TK85	Pseudomonas_phage	1.5e-28	48.1
WP_057793524.1\|14830_17476_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	1.1e-32	21.5
WP_057793526.1\|17654_19286_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.3e-148	50.6
WP_057793528.1\|19345_20638_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	2.7e-133	59.3

DBSCAN-SWA_2

261224 : 270959

Turkeypox_virus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082746027.1\|261224_262529_-	alkaline phosphatase family protein	A0A0M3PB47	Turkeypox_virus	2.6e-43	32.3
WP_057793871.1\|262602_263616_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.4e-108	57.1
WP_012517258.1\|264006_264222_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_057793873.1\|264580_265027_+	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	5.1e-23	41.8
WP_063456559.1\|265168_266950_+	DNA primase	A0A1S5RFR1	Helicobacter_phage	2.0e-46	32.9
WP_013785437.1\|267274_269101_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.3e-35	33.0
WP_057793877.1\|269339_270959_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.7e-31	34.8

DBSCAN-SWA_3

1700465 : 1714291

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063456764.1\|1700465_1701632_+	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	4.6e-39	33.8
WP_063456765.1\|1701628_1704436_+	glycosyltransferase	A0A1V0SAH6	Catovirus	2.9e-15	37.1
WP_063456766.1\|1704563_1706396_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	5.2e-138	45.5
WP_063456767.1\|1706462_1707803_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_063456768.1\|1707816_1708701_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.7e-97	59.2
WP_063456769.1\|1708744_1709290_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	8.7e-49	56.6
WP_063456770.1\|1709299_1710160_+	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	3.9e-35	35.8
WP_063456771.1\|1710178_1711258_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.2e-97	53.5
WP_063456772.1\|1711345_1713061_+	glycosyltransferase	NA	NA	NA	NA
WP_063457259.1\|1713124_1714291_+	nucleotide sugar dehydrogenase	O41091	Paramecium_bursaria_Chlorella_virus	1.7e-110	55.0

DBSCAN-SWA_4

3620318 : 3630347

uncultured_Caudovirales_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013784150.1\|3620318_3620984_+	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	1.4e-35	45.2
WP_061997315.1\|3621098_3621488_+	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	3.2e-13	34.2
WP_061997316.1\|3621487_3621850_+	sulfur reduction protein DsrE	NA	NA	NA	NA
WP_063457083.1\|3621849_3622209_+	hypothetical protein	NA	NA	NA	NA
WP_063457084.1\|3622399_3622747_+	TusE/DsrC/DsvC family sulfur relay protein	NA	NA	NA	NA
WP_061997318.1\|3622807_3623626_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_063457085.1\|3623828_3625121_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	3.0e-95	45.2
WP_057791932.1\|3625131_3625515_-	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	9.3e-05	32.6
WP_057791934.1\|3625520_3626855_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	1.4e-71	37.4
WP_063457086.1\|3626865_3627666_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_063457087.1\|3627671_3630347_-	DNA translocase FtsK	G1FGP1	Mycobacterium_phage	4.2e-88	51.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP015345

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection