CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP015741	Shinella sp. HZN7 plasmid pShin-05, complete sequence	0 crisprs	NA	0	1
NZ_CP015748	Shinella sp. HZN7 plasmid pShin-12, complete sequence	0 crisprs	NA	0	0
NZ_CP015743	Shinella sp. HZN7 plasmid pShin-07, complete sequence	0 crisprs	NA	0	1
NZ_CP015736	Shinella sp. HZN7 chromosome, complete genome	4 crisprs	csa3,cas9,cas1,cas2,WYL,DEDDh	15	6
NZ_CP015747	Shinella sp. HZN7 plasmid pShin-11, complete sequence	0 crisprs	NA	0	0
NZ_CP015746	Shinella sp. HZN7 plasmid pShin-10, complete sequence	0 crisprs	NA	0	0
NZ_CP015744	Shinella sp. HZN7 plasmid pShin-08, complete sequence	0 crisprs	NA	0	0
NZ_CP015737	Shinella sp. HZN7 plasmid pShin-01, complete sequence	0 crisprs	WYL	0	0
NZ_CP015745	Shinella sp. HZN7 plasmid pShin-09, complete sequence	0 crisprs	NA	0	1
NZ_CP015742	Shinella sp. HZN7 plasmid pShin-06, complete sequence	0 crisprs	csa3,DEDDh	0	1
NZ_CP015739	Shinella sp. HZN7 plasmid pShin-03, complete sequence	0 crisprs	NA	0	0
NZ_CP015740	Shinella sp. HZN7 plasmid pShin-04, complete sequence	0 crisprs	NA	0	0
NZ_CP015738	Shinella sp. HZN7 plasmid pShin-02, complete sequence	2 crisprs	DEDDh,csa3	2	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

773 : 63147

Stx2-converting_phage(12.5%)

transposase,integrase

attL 29094:29108|attR 63060:63074

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_145926104.1\|773_1719_+\|transposase	IS630 family transposase	A0A2P0VP61	Tetraselmis_virus	5.3e-09	21.8
WP_084438671.1\|1867_2416_+	YqhA family protein	K4K6D8	Caulobacter_phage	1.3e-12	31.8
WP_064334242.1\|3928_5290_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_064334243.1\|5509_5758_+	hypothetical protein	NA	NA	NA	NA
WP_168168996.1\|5769_7155_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_064334245.1\|7235_8900_-	electron transfer flavoprotein-ubiquinone oxidoreductase	NA	NA	NA	NA
WP_145926105.1\|9011_9362_+	hypothetical protein	NA	NA	NA	NA
WP_064334246.1\|9460_10390_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_024899813.1\|10467_11217_-	electron transfer flavoprotein subunit beta/FixA family protein	NA	NA	NA	NA
WP_084438673.1\|11523_12873_-	MFS transporter	Q6JIH2	Burkholderia_virus	1.1e-47	30.6
WP_024899816.1\|13319_14495_+	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_168169004.1\|14508_15417_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_064334247.1\|15539_15917_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_024899819.1\|16019_18035_+	6-hydroxypseudooxynicotine oxidase	NA	NA	NA	NA
WP_064334248.1\|18229_18523_+	hypothetical protein	NA	NA	NA	NA
WP_064334249.1\|18725_19397_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_168168997.1\|19808_20947_-\|transposase	IS3 family transposase	A0A2P1JR32	Mycobacterium_phage	9.4e-21	31.9
WP_064334251.1\|21089_23300_-	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.7e-13	36.5
WP_024899825.1\|24194_25229_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_064334252.1\|27090_28167_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_064334253.1\|28560_29241_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
29094:29108	attL	NA	NA	NA	NA
WP_064334254.1\|29416_30451_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_024899989.1\|30482_31283_-	ABC transporter permease	NA	NA	NA	NA
WP_024899990.1\|31275_32181_-	ABC transporter permease	Q6GZ02	Mycoplasma_phage	4.6e-10	26.1
WP_024899991.1\|32183_33257_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-27	35.7
WP_024899992.1\|33433_34066_-	isochorismatase family protein	NA	NA	NA	NA
WP_064334255.1\|34127_35156_-	hypothetical protein	NA	NA	NA	NA
WP_024899994.1\|35182_35965_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_145926120.1\|35977_36679_-	Asp/Glu racemase	NA	NA	NA	NA
WP_024899996.1\|37265_37673_+	hypothetical protein	NA	NA	NA	NA
WP_024899997.1\|37956_39354_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_064334256.1\|39383_40697_+	FAD-dependent oxidoreductase	A0A2K9L3H9	Tupanvirus	6.4e-13	21.8
WP_084438674.1\|40803_41010_-	hypothetical protein	NA	NA	NA	NA
WP_064334257.1\|41011_42667_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.9e-103	46.5
WP_064334258.1\|42712_43060_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	6.4e-37	61.7
WP_037407864.1\|43056_43467_-	IS66 family insertion sequence hypothetical protein	A0A1B0YZU7	Pseudomonas_phage	7.6e-05	41.9
WP_084438675.1\|43541_43733_-	hypothetical protein	NA	NA	NA	NA
WP_084438676.1\|43882_46132_-	nicotine dehydrogenase subunit alpha NdhA	NA	NA	NA	NA
WP_024900002.1\|46128_46596_-	(2Fe-2S)-binding protein	A0A0P0IVM8	Acinetobacter_phage	4.0e-10	29.5
WP_145926109.1\|46879_47548_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_064334260.1\|47710_48613_-	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_024900006.1\|48699_49098_-	DoxX family protein	NA	NA	NA	NA
WP_024900007.1\|49129_49510_-	glutathione S-transferase domain-containing protein	NA	NA	NA	NA
WP_035209847.1\|50509_51424_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_064334261.1\|51808_52621_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	8.2e-35	37.7
WP_145926110.1\|52610_54137_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	8.8e-22	26.1
WP_064334262.1\|54187_54445_+	hypothetical protein	NA	NA	NA	NA
WP_064334263.1\|54444_54915_+	hypothetical protein	NA	NA	NA	NA
WP_064334264.1\|55002_56151_-	DUF1612 and helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_064334265.1\|56165_57827_+\|transposase	transposase	NA	NA	NA	NA
WP_064334266.1\|58169_58601_-	hypothetical protein	NA	NA	NA	NA
WP_064334267.1\|58587_58866_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_064334268.1\|58943_60107_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_064334269.1\|60129_60441_+	hypothetical protein	NA	NA	NA	NA
WP_145926111.1\|60528_60780_+	hypothetical protein	NA	NA	NA	NA
WP_035089229.1\|60841_61597_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.3e-55	46.1
WP_064332397.1\|61611_63147_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	8.0e-116	43.6
63060:63074	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP015738

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015738_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015738_1

193329-193406

Orphan

Consensus_repeat	Method
GGCAATGACCTCATGTATGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015738_1

>merge|NZ_CP015738|1|193329-193406|CRISPRCasFinder
GGCAATGACCTCATGTATGGCGGGTATGGTCGCGACACGATGAGTGGCGGCAATGGCAACGACCTCATGTATGGCGGC

>NZ_CP015738|1|1|193329-193406|CRISPRCasFinder
GGCAATGACCTCATGTATGGCGG	GTATGGTCGCGACACGATGAGTGGCGGCAAT
GGCAACGACCTCATGTATGGCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015738.1\|WP_064333452.1\|182107_182845_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP015738.1\|WP_064333458.1\|188509_189451_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP015738.1\|WP_064333454.1\|183762_184485_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP015738.1\|WP_145926064.1\|184459_185896_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP015738.1\|WP_064333456.1\|185974_186991_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380652
NZ_CP015738.1\|WP_064333467.1\|198698_199745_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270307
NZ_CP015738.1\|WP_064333466.1\|197658_198687_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270307
NZ_CP015738.1\|WP_064333459.1\|189447_190398_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP015738.1\|WP_064333469.1\|201019_201823_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224098
NZ_CP015738.1\|WP_064333468.1\|199729_201016_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224097
NZ_CP015738.1\|WP_064333470.1\|201833_202577_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP015738.1\|WP_064333461.1\|191469_192339_+\|bile-acid:sodium-symporter-family-protein	unknown	unknown	gnl\|CDD\|223462
NZ_CP015738.1\|WP_064333463.1\|194471_195335_+\|transketolase	unknown	unknown	gnl\|CDD\|238970
NZ_CP015738.1\|WP_145926065.1\|194076_194364_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015738.1\|WP_064333453.1\|182841_183732_+\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200563
NZ_CP015738.1\|WP_064333471.1\|202596_203274_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP015738.1\|WP_064333457.1\|187055_188513_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP015738.1\|WP_064333465.1\|196320_197622_+\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223080
NZ_CP015738.1\|WP_064333464.1\|195331_196309_+\|transketolase	unknown	unknown	gnl\|CDD\|226467
NZ_CP015738.1\|WP_064333460.1\|190414_191329_+\|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl\|CDD\|225921

Protein	Function_ID	Function_description	E-value
NZ_CP015738.1\|WP_064333452.1\|182107_182845_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.20304e-66
NZ_CP015738.1\|WP_064333458.1\|188509_189451_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.33143e-49
NZ_CP015738.1\|WP_064333454.1\|183762_184485_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	6.02513e-42
NZ_CP015738.1\|WP_064333463.1\|194471_195335_+\|transketolase	gnl\|CDD\|238970	cd02012, TPP_TK, Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.	7.52982e-108
NZ_CP015738.1\|WP_064333456.1\|185974_186991_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380652	cd19997, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate binding protein such as CUT2. Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their substrate specificity is not known in detail.	9.70853e-139
NZ_CP015738.1\|WP_064333467.1\|198698_199745_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270307	cd13589, PBP2_polyamine_RpCGA009, The periplasmic-binding component of an uncharacterized ABC transport system from Rhodopseudomonas palustris CGA009 and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic binding domain that serves as the primary high-affinity receptor of an uncharacterized ABC-type polyamine transporter from Rhodopseudomonas palustris Cga009 and related proteins from other bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.3637e-76
NZ_CP015738.1\|WP_064333466.1\|197658_198687_+\|extracellular-solute-binding-protein	gnl\|CDD\|270307	cd13589, PBP2_polyamine_RpCGA009, The periplasmic-binding component of an uncharacterized ABC transport system from Rhodopseudomonas palustris CGA009 and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic binding domain that serves as the primary high-affinity receptor of an uncharacterized ABC-type polyamine transporter from Rhodopseudomonas palustris Cga009 and related proteins from other bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.95226e-81
NZ_CP015738.1\|WP_064333459.1\|189447_190398_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.26057e-60
NZ_CP015738.1\|WP_064333469.1\|201019_201823_+\|ABC-transporter-permease	gnl\|CDD\|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	1.2014e-80
NZ_CP015738.1\|WP_064333468.1\|199729_201016_+\|ABC-transporter-permease	gnl\|CDD\|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	7.62144e-78
NZ_CP015738.1\|WP_064333470.1\|201833_202577_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	8.53998e-71
NZ_CP015738.1\|WP_064333461.1\|191469_192339_+\|bile-acid:sodium-symporter-family-protein	gnl\|CDD\|223462	COG0385, COG0385, Predicted Na+-dependent transporter [General function prediction only].	1.14242e-36
NZ_CP015738.1\|WP_145926064.1\|184459_185896_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.30829e-47
NZ_CP015738.1\|WP_064333453.1\|182841_183732_+\|polysaccharide-deacetylase	gnl\|CDD\|200563	cd10938, CE4_HpPgdA_like, Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins. This family is represented by a peptidoglycan deacetylase (HP0310, HpPgdA) from the gram-negative pathogen Helicobacter pylori. HpPgdA has the ability to bind a metal ion at the active site and is responsible for a peptidoglycan modification that counteracts the host immune response. It functions as a homotetramer. The monomer is composed of a 7-stranded barrel with detectable sequence similarity to the 6-stranded barrel NodB homology domain of polysaccharide deacetylase (DCA)-like proteins in the CE4 superfamily, which removes N-linked or O-linked acetyl groups from cell wall polysaccharides. In contrast to typical NodB-like DCAs, HpPgdA does not exhibit a solvent-accessible polysaccharide binding groove, suggesting that the enzyme binds a small molecule at the active site.	2.92802e-100
NZ_CP015738.1\|WP_064333471.1\|202596_203274_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.92868e-47
NZ_CP015738.1\|WP_064333457.1\|187055_188513_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	7.21413e-170
NZ_CP015738.1\|WP_064333465.1\|196320_197622_+\|aspartate-aminotransferase-family-protein	gnl\|CDD\|223080	COG0001, HemL, Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism].	3.86465e-155
NZ_CP015738.1\|WP_064333464.1\|195331_196309_+\|transketolase	gnl\|CDD\|226467	COG3958, COG3958, Transketolase, C-terminal subunit [Carbohydrate transport and metabolism].	3.13538e-97
NZ_CP015738.1\|WP_064333460.1\|190414_191329_+\|SMP-30/gluconolactonase/LRE-family-protein	gnl\|CDD\|225921	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism].	3.61542e-95

>NZ_CP015738.1|WP_064333461.1|191469_192339_+|bile-acid:sodium-symporter-family-protein
MEQSALIDIGLPIAVFIIMAGIGMTLAPVDFQRVVTQPKALVWGIVAALVLMPLVALLLAMLMGLPPEIAVGLVVVAACPIGTTSSLFSYLARGDLALSIALSAVGSLVAIVTLPLFANFAIERLSDGDARVYLPVLRTIGVMIAIILFPVIVGMGIRRKAPGFAARAERLVGAFGLLVLVALIVGIGISVYERWVEILVSAGPAVVALVVCAVALGLLGSRALGLSAAEAVTVTLSISIRNAAIGMVLAITMMHSPEIAVPPALFGLLMYATGFSLVAYGRMTIKAPA
>NZ_CP015738.1|WP_064333460.1|190414_191329_+|SMP-30/gluconolactonase/LRE-family-protein
MASESPYEIHDPRFLHLIVGSARLEELHTGCRWAEGPVWFSDANQLLWSDIPNQRILRWTPDGGVSVYRQPSNFANGHTRDRQGRLVSCEHGLRRVTRTEIDGSITVLAESHAGKRLNSPNDVVVRSDGSVWFTDPTYGILSDYEGYRAEPEQAARNVYRLDPETGAIEAVIGDFAQPNGLAFSPDERTLYVADSAASHDPALPRHIRAFDVADGRRLQNGRVFCHIDTGIPDGIRTDVSGNLWSSAGDGVHCFDPAGTLIGKIRVPQTVANLTFGGPRRNRLFITATASLYSIYLAISGSQRP
>NZ_CP015738.1|WP_064333459.1|189447_190398_+|ABC-transporter-permease
MTLFRHLAQKSWIWSWIAAVIVWLATISVTGGASAIGLTQAALTFAAFSIIVGIGQMFVITLGPGNIDLSVPATMTLAGTVALKLMNVENGMILPGLVVAILIGVAVGIGNYALIKTLRIPPIIATLSMSFIVQSTAIWTNRGLRIKPPPFLADFTTASTFGVPNVALIALVLSLVAWLLLEKTLYGRWISAIGQSMPAARMAGIPVDGARFVTYVFCAVLAALAGYLLACFSGGAALNMGSEYLLMSIAVVVIGGTAVAGGDSNVPGVWGASLFMFLVVSMLNTYGLGAGVRLIMTGLIIISVIMLAGGRRPGAR
>NZ_CP015738.1|WP_064333458.1|188509_189451_+|ABC-transporter-permease
MRMSNDAVRLLIPALSLTVLLAAVFWLQPRAMSYVGLNLLFNLAVPIALATIAQMLVMAVNDLDLSMGAFVSFVACVTATFLRDAPLVGGLILLGAIGVYALLGVVIHLRNLPSIVVTLGMSFVWAGLAVLLLPAPGGQAPDWARALMTMKPPVVPMAIVASIVIAAIAHLVVMRSSLGVLMRGVGGNQRSVERAGWSVILARAAAYGLAGLFAVLAGIALVGLTTSADANIALRYTLLSIAGVILGGGEFIGGRVSPIGAVIGALTLTLAGSFLSFLRISPDWQIGAQGAILITVLALRLVLNRIENRERRR
>NZ_CP015738.1|WP_064333457.1|187055_188513_+|sugar-ABC-transporter-ATP-binding-protein
MTGEMGKPVIAVAEARVSFGAVRALDGVTLSIMPGECVGLVGHNGAGKSTIVSVINGGLTPHAGGVAGDDGAPARAYGITAARARGVRCVFQELSLCPNLTIVENVRLMHRPLGGFGWRRRARAVIEASLAAIFPGHGIESDRTVGELSIAERQMVEIAMAFSDAGVAPRLVILDEPTSSLDASLAEQMLVHVRRFVAAGGSVVFISHILGEILATADRIVVMKDGRIVASRPAADFSERSLVEAMGSVVKGEAHRRASRDLTGAPVVLEQGGRGLPFLARAGEIVGLAGLAGHGQTDMLMALHAAGSGAWLPARDPAVTFVAGDRRLNGVFELWSILRNLSIASLGDMTRSGLVRTGEEDARGAEWQRRIEIRTPDMGNRILSLSGGNQQKVLFARALATRAPVVLMDDPMRGVDVGTKQEVYEIVRQEAATGRTFVWYSTEMEEVCLCDRVYVFREGRIVAELSGDAVGEANILAASFEGAAA
>NZ_CP015738.1|WP_064333456.1|185974_186991_+|ABC-transporter-substrate-binding-protein
MGIRKMLLASAVAACVAVPVSAFADTSGKKIALSNNYAGNSWRQAMLTSWDKVTGEAVKAGAVAAADPFTTAENQATEQAAQIQNMILQGYDAIVVNAASPTALNGAVKEACDAGITVVSFDGIVTEPCAWRIAVDFKEMGRSQVEYLSGKLPEGGNLLEIRGLAGVFVDDEISAGIHEGVKQFPQFKVVGSVHGDWAQDVAQKAVAGILPSLPEIVGVVTQGGDGYGAAQAIAAAKRPMPVIVMGNREDELKWWKEQKDANGYETMSVSIAPGVSTLAFWVAQQILDGKEVKKDLVVPFLRIDQDNLEANLATTQAGGVANVEYSQADAIKVIEAAQ
>NZ_CP015738.1|WP_145926064.1|184459_185896_-|sensor-histidine-kinase
MRENGRPVQARLGKSFAGFAREVAGSRKTRLCLSALTGGRRRRGRPPPGGCSPMLQLAPAALFEHYLGISRLLAGQLDFRSAIRSVANEVAHIIPHDHLDVCVLVEDGNYHTAYETGIDTAWGDLEGAPVVYSPIRSLLWGEVDYLLSDDATVDPRFRFEGAFRAPIDEQSLRSRIHVPMKVEGAIIAALSCSSQSAGLYTLDDVERARVIADLLTPYFFALRAAEQAQRSAIVEAEARAREEGLRLGALRLTEALEQERQRIGMDLHDQTLADLTRLARRVEQLSLSGEIGPDALEPVSRSLQHCMHDLRQIIEQAKPSVLQLFGLAQAVENHLDRSVRDSGMPIRWALADETAGALDKLEPTVSVALFRIAQEAINNAVRHARPTTLAVRLRIEAESLVLDVVDDGCGVVRTRGRIGSGVENMKTRARLISASCAIGAGRNNSGTTVTVRLPLAPQGGAAAPCEGGTGDESPDRGG
>NZ_CP015738.1|WP_064333454.1|183762_184485_-|response-regulator-transcription-factor
MKVLIVEDDPLHRSYLHEAVSAALPECETVIEAENGLSGEKLARDHKSAHIVMDLQMATRNGIEAARTIWKERPETRILFWSNYSDEAYVRGVSRIVPDGAAYGYVLKSASDERLKLALRSIFVESQCVIDREIRGVQQKSLGQTNGFTDSEYEILVDIALGLTDRAIARRRNLSLRSVQNRLQQLYDKLDVYQSTGEDSEDARFNLRTRAVTTALLRKLLNYSALEKAEADLQEWLTNL
>NZ_CP015738.1|WP_064333453.1|182841_183732_+|polysaccharide-deacetylase
MIKNPIPWPNGAKCAACITFDMDADSLIHIAHPEDGHSRVAGISMLQYGPKVAIPRIVESYRQLGIRQTFFVPAWCIERYPQAIEAILEGGHELAHHGFLHEHPRELSDEDEAYWLDRGIEVIVKASGRRPRGWRAPLYNFSHRSADLLVARGFEYDASLMGDDIPYLLECEAGSLVELPSHWGLDDWPQYVQSIDLDYMMPVRAPEQGFAAFAQEFEAAWRHGALWVPVVHPFATGRLARWEVVHRFLEQVLTRGDVWFAPMEEIAAHVRAVVDKGLWSPRIDRLPYYAEPVRVR
>NZ_CP015738.1|WP_064333452.1|182107_182845_+|SDR-family-oxidoreductase
MSRRVLITGAYRGIGAACALVFAATGARVALADIRRPDETAAAAAGAGAAETLALSCDVSDESAVLAVGDAVKERFGGLDVVVHCAGVIHEAPLLDTSAADFDRVIAINLRGSFLVGKMAIGLMEGTAEAPARVILIASDMAYYGRETFSPYVASKHGVLGLTRSWAKEFAPRILVNAICPGPIDTDMLGAANMSAEWRARELAIPLARFGQPEEIGELALFLAGSGGRYFTGQGVGSNGGSIMP
>NZ_CP015738.1|WP_145926065.1|194076_194364_-|hypothetical-protein
MRKGRIARHVRRNSLSIMGVSVAARAAASRKGRSCGASWLLPRIMKDGAERGPAEGERTLLPGHAAKDGKSFARSQPRALRFRVLDRTPLPIAKR
>NZ_CP015738.1|WP_064333463.1|194471_195335_+|transketolase
MARDDDLLSGEQLAFLEERARFVRLETLRLISIAKVGHYTSVFSCAEIFAALYYDVMRLRRGEPAWVDRDRFLMGKGHAAVGLFPILADLGFFDPAWLESYTRLGSPLGDHPDMTKVPGVDFSSGSIGHALSNGVGMLLGARFQKRDFNAFVLLGDGEMQEGQVWEAALSAAAHDLSNLVAIVDRNGYQLDGKVDDVMAIEPLDEKWRAFGWEVHTVDGHDLAALTTLLRRVKADRTREKPCCIIARTVKGKGIDYMETEPGWHLGYLGAEDEARARETILNTVISQ
>NZ_CP015738.1|WP_064333464.1|195331_196309_+|transketolase
MTQLLSKDSWQYREINRRAPSLPTLSNALIALAEAGHPVMAGTADLQYSNGLSGFAQRYPERFVQFGISEQNMVSAAAGMATTGVIPYVATFASFLALLCCEQIRMDVAYCRQPVRLIGHHTGISLGFYGTSHHATEDIAIMRSIANLAVVSTADGPALDAALRATVDYPLPIYFRIHRGHDPVVYENGVPFELGKAIVHGIGRDITIIAAGYPVHGARRAMEELNAAGHSVGLIDMHSIKPLDEEAIIEASARSKVILTVEEHTILGGLGGAVAEVLAEKGRGARLVRHGIRDEYSLIAPPTHLYRHYRLDGDGIRAVALESLA
>NZ_CP015738.1|WP_064333465.1|196320_197622_+|aspartate-aminotransferase-family-protein
MSTNNETIAARAESVIPGGLLSPSRRLGAPIAFARAEGAYLYDADGNRYTDYHCAFGANVLGHRPPAVAAAIAETAENLDLIGAGVLELEVEVAELLVNAIPCAEQVAFCSSGSEATYHALRLARAYTGRKQIIKFQGGYHGWHDYVAMNGQSSRQMIGSYDPMSDGMLFDAARHTAILPYNDAGAVEDYIRKNPGEVAAIIVEPIAHNMGAVIAEKQFLADLRRITSEHGVVLIFDEVITGFRHALGGYQSIVGVTPDLATFGKAATSGYPIGILAGRREIMERVGRTGEGAVFMGGTFNGTPASMAAVKATIGELARPGVYERLFELGAYLRGEIDGIIARHGLKAQAAGFGSVWLVYFFDGAFRDYTDLLRNDNDLDMRFRRALIAGRQVFQPLQLKRLYLSLSHDRAVLDDTLELIDTTMAGLARSVAA
>NZ_CP015738.1|WP_064333466.1|197658_198687_+|extracellular-solute-binding-protein
MRTRFFAMMASAALVVSSPALARDLTVVGFGGATQDVMRETLFKPYQDKAGTPLLEESYTGGIAKVKAMVETGTTTWDVVQMDENEMILACDQGLLEPFDWASLPNSADIIAPAKSDCGVGAFVWSKILAYDGDKTSGVTSWADFWNLDKWPGKRGLRKQARMTLEIALLADGAKPEELYDILATREGQDRAFAKLDEIKPSIQWWESGAQPMEWLASGEVTMTSAYNGRVIAANQQGRHFRMSWTHQLYAMDFWAIPKGGNRDQAFDIVNFMTSPEPQKAFAEKMVYGVTNAKAMDSIAADIKPQLPTAEENMAGALAVSTPFWVDHEEELQQRFNRWVAQ
>NZ_CP015738.1|WP_064333467.1|198698_199745_+|ABC-transporter-substrate-binding-protein
MTYRRFFGGLGMLAVLAGAPAAFADAGRLTVVGAGGVLQDAERKAFFEPFAAASGVVLTEDSYSGQMAKVRAMVDSGSVSWDVMQVEQNTLLSGCAEGLFEELDWSRIGKREDFIPEAYSDCGVGAFVWSMVPSYDKAKLADGPKTWADLWNVEKWPGKRGFRQTAKMTLEIALLSDGVAKDAVYDVLATDEGQDRAFAKLDEIKSSILWWTTGAESVERLAAGDVVATATFNGRVAAANASGKDFALIWDGQVFGIDYWGIVKGSPNRENAEKFIAFASTESAQAAFPQHIAYGVTNLAAIRGVKPEIAKDLPTTEANMAAAVALDTEFWADHGEALEARFATWRAQ
>NZ_CP015738.1|WP_064333468.1|199729_201016_+|ABC-transporter-permease
MARAMTSDVLLRPRAGAADGQQGRVSALAAGFRADRRRQTIVSLVLIGPLVAFIVFAFVLPLGTMLFHAINNPEVRNALPMTLASLEGWDGVDTPPDAAFEALAADIRAGADPKVLAEAGRRLNYEITGFRSLLAKTVRTVRKAPVEPARAQLLAIDGNWDNPAYWRVIQRNGAPLTAFYLLSAVDLRPGENGGVQMAPPEERLFLSTLMRTLTISALVTVICLFVAYPVANAIVAIGGRFSAIMLACVLLPFWTSLLVRTSAWIVILQKEGVVNRLLQALNITDAPLELVFNRTGLYIAMVHILLPFMVLPLVSVMKGISPSYVKASASLGAGPVTTFLRVYLPLTLPGVGAGCLLTFIISAGYYVTPTLVGGASDQMLSYFVAFYANTTINWGMSAALGVLLLACILALYGIVGRIVGIGRIVGME
>NZ_CP015738.1|WP_064333469.1|201019_201823_+|ABC-transporter-permease
MPVALRRVQIAFCCLAMVFLIGPTLVIIPISFSSANFLSYPLPGFSLQWYEKILQPQPWMSALLNSLIIGVGATLVSTVLGTLAALGMSRGRLPARSMILAVVISPMIVPVVISGVGMYFFFARLGLVASFLGLVLAHAVLAVPFVLITVTATLKNFDMNLVRAAASLGASPFHAFRTVTLPLIAPGVISGALFAFVFSFDEVVVALFISGPGQRTLPRQMFDGLRDNIDPSILAMSTLLVIISIVLMGGGALAQKRAAANRSIANL
>NZ_CP015738.1|WP_064333470.1|201833_202577_+|SDR-family-oxidoreductase
MIIVTGATHGIGRACVEKLAAAGARVVATGRDAAAGRALEEIGPGVTFVPGDVGREEDCRRVVDRALDLGGGRLAGLVNNAGMSKRISFAAATQDDWDEVLAVNARSTFLFIRHALEGLRRGRGSVVNIASIAGKTGEEGLAVYCASKAAVIGLTQALALEFGEEVRFNAVCPGQIGTRMMDRIMSDALRRKQLELRIPANRFGAPQEVADVVAWLLSDQSTYVNGTVVTVDGGETAGLRTPRIAQV
>NZ_CP015738.1|WP_064333471.1|202596_203274_-|GntR-family-transcriptional-regulator
MSVMEMQPGEVGSLSARIYTKVREGLIVGNFAPGDRLLMQDLAEQLGTSVTPVREACLRLVSEQALELRSGRFVTVPDLSRARYIQIKLIRMALEGLAAEHAADHVTAADLAQLEAFHAAFVKNEKAGNLEAARSSNRAFHFGVYRLSRMPMLVGQIESMWVSMGPILNVYYREIPHNYTGAEEHVHLIEALRAGDKKKARQAIENDIQRASPSLLRYFEERGAA

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Crispr_ID: NZ_CP015738_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015738_2

193533-193609

Orphan

Consensus_repeat	Method
GGCAATGACCTCATGTATGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015738_2

>merge|NZ_CP015738|2|193533-193609|CRISPRCasFinder
AGCAATGACCACATGTCGGGCGGCAACGGCAACGATCGCATGTGGGGCCAGGGCGGCAATGACAAGCTTTATGGCGG

>NZ_CP015738|2|2|193533-193609|CRISPRCasFinder
AGCAATGACCACATGTCGGGCGG	CAACGGCAACGATCGCATGTGGGGCCAGGGC
GGCAATGACAAGCTTTATGGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015738.1\|WP_064333452.1\|182107_182845_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP015738.1\|WP_064333458.1\|188509_189451_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP015738.1\|WP_064333454.1\|183762_184485_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP015738.1\|WP_145926064.1\|184459_185896_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP015738.1\|WP_064333456.1\|185974_186991_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380652
NZ_CP015738.1\|WP_064333467.1\|198698_199745_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270307
NZ_CP015738.1\|WP_064333466.1\|197658_198687_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270307
NZ_CP015738.1\|WP_064333459.1\|189447_190398_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NZ_CP015738.1\|WP_064333469.1\|201019_201823_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224098
NZ_CP015738.1\|WP_064333468.1\|199729_201016_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224097
NZ_CP015738.1\|WP_064333470.1\|201833_202577_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP015738.1\|WP_064333461.1\|191469_192339_+\|bile-acid:sodium-symporter-family-protein	unknown	unknown	gnl\|CDD\|223462
NZ_CP015738.1\|WP_064333463.1\|194471_195335_+\|transketolase	unknown	unknown	gnl\|CDD\|238970
NZ_CP015738.1\|WP_145926065.1\|194076_194364_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015738.1\|WP_064333453.1\|182841_183732_+\|polysaccharide-deacetylase	unknown	unknown	gnl\|CDD\|200563
NZ_CP015738.1\|WP_064333471.1\|202596_203274_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP015738.1\|WP_064333457.1\|187055_188513_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP015738.1\|WP_064333465.1\|196320_197622_+\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223080
NZ_CP015738.1\|WP_064333464.1\|195331_196309_+\|transketolase	unknown	unknown	gnl\|CDD\|226467
NZ_CP015738.1\|WP_064333460.1\|190414_191329_+\|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl\|CDD\|225921

Protein	Function_ID	Function_description	E-value
NZ_CP015738.1\|WP_064333452.1\|182107_182845_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.20304e-66
NZ_CP015738.1\|WP_064333458.1\|188509_189451_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.33143e-49
NZ_CP015738.1\|WP_064333454.1\|183762_184485_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	6.02513e-42
NZ_CP015738.1\|WP_064333463.1\|194471_195335_+\|transketolase	gnl\|CDD\|238970	cd02012, TPP_TK, Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.	7.52982e-108
NZ_CP015738.1\|WP_064333456.1\|185974_186991_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380652	cd19997, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate binding protein such as CUT2. Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their substrate specificity is not known in detail.	9.70853e-139
NZ_CP015738.1\|WP_064333467.1\|198698_199745_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270307	cd13589, PBP2_polyamine_RpCGA009, The periplasmic-binding component of an uncharacterized ABC transport system from Rhodopseudomonas palustris CGA009 and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic binding domain that serves as the primary high-affinity receptor of an uncharacterized ABC-type polyamine transporter from Rhodopseudomonas palustris Cga009 and related proteins from other bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.3637e-76
NZ_CP015738.1\|WP_064333466.1\|197658_198687_+\|extracellular-solute-binding-protein	gnl\|CDD\|270307	cd13589, PBP2_polyamine_RpCGA009, The periplasmic-binding component of an uncharacterized ABC transport system from Rhodopseudomonas palustris CGA009 and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic binding domain that serves as the primary high-affinity receptor of an uncharacterized ABC-type polyamine transporter from Rhodopseudomonas palustris Cga009 and related proteins from other bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.95226e-81
NZ_CP015738.1\|WP_064333459.1\|189447_190398_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.26057e-60
NZ_CP015738.1\|WP_064333469.1\|201019_201823_+\|ABC-transporter-permease	gnl\|CDD\|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	1.2014e-80
NZ_CP015738.1\|WP_064333468.1\|199729_201016_+\|ABC-transporter-permease	gnl\|CDD\|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	7.62144e-78
NZ_CP015738.1\|WP_064333470.1\|201833_202577_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	8.53998e-71
NZ_CP015738.1\|WP_064333461.1\|191469_192339_+\|bile-acid:sodium-symporter-family-protein	gnl\|CDD\|223462	COG0385, COG0385, Predicted Na+-dependent transporter [General function prediction only].	1.14242e-36
NZ_CP015738.1\|WP_145926064.1\|184459_185896_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.30829e-47
NZ_CP015738.1\|WP_064333453.1\|182841_183732_+\|polysaccharide-deacetylase	gnl\|CDD\|200563	cd10938, CE4_HpPgdA_like, Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins. This family is represented by a peptidoglycan deacetylase (HP0310, HpPgdA) from the gram-negative pathogen Helicobacter pylori. HpPgdA has the ability to bind a metal ion at the active site and is responsible for a peptidoglycan modification that counteracts the host immune response. It functions as a homotetramer. The monomer is composed of a 7-stranded barrel with detectable sequence similarity to the 6-stranded barrel NodB homology domain of polysaccharide deacetylase (DCA)-like proteins in the CE4 superfamily, which removes N-linked or O-linked acetyl groups from cell wall polysaccharides. In contrast to typical NodB-like DCAs, HpPgdA does not exhibit a solvent-accessible polysaccharide binding groove, suggesting that the enzyme binds a small molecule at the active site.	2.92802e-100
NZ_CP015738.1\|WP_064333471.1\|202596_203274_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.92868e-47
NZ_CP015738.1\|WP_064333457.1\|187055_188513_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	7.21413e-170
NZ_CP015738.1\|WP_064333465.1\|196320_197622_+\|aspartate-aminotransferase-family-protein	gnl\|CDD\|223080	COG0001, HemL, Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism].	3.86465e-155
NZ_CP015738.1\|WP_064333464.1\|195331_196309_+\|transketolase	gnl\|CDD\|226467	COG3958, COG3958, Transketolase, C-terminal subunit [Carbohydrate transport and metabolism].	3.13538e-97
NZ_CP015738.1\|WP_064333460.1\|190414_191329_+\|SMP-30/gluconolactonase/LRE-family-protein	gnl\|CDD\|225921	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism].	3.61542e-95

>NZ_CP015738.1|WP_064333461.1|191469_192339_+|bile-acid:sodium-symporter-family-protein
MEQSALIDIGLPIAVFIIMAGIGMTLAPVDFQRVVTQPKALVWGIVAALVLMPLVALLLAMLMGLPPEIAVGLVVVAACPIGTTSSLFSYLARGDLALSIALSAVGSLVAIVTLPLFANFAIERLSDGDARVYLPVLRTIGVMIAIILFPVIVGMGIRRKAPGFAARAERLVGAFGLLVLVALIVGIGISVYERWVEILVSAGPAVVALVVCAVALGLLGSRALGLSAAEAVTVTLSISIRNAAIGMVLAITMMHSPEIAVPPALFGLLMYATGFSLVAYGRMTIKAPA
>NZ_CP015738.1|WP_064333460.1|190414_191329_+|SMP-30/gluconolactonase/LRE-family-protein
MASESPYEIHDPRFLHLIVGSARLEELHTGCRWAEGPVWFSDANQLLWSDIPNQRILRWTPDGGVSVYRQPSNFANGHTRDRQGRLVSCEHGLRRVTRTEIDGSITVLAESHAGKRLNSPNDVVVRSDGSVWFTDPTYGILSDYEGYRAEPEQAARNVYRLDPETGAIEAVIGDFAQPNGLAFSPDERTLYVADSAASHDPALPRHIRAFDVADGRRLQNGRVFCHIDTGIPDGIRTDVSGNLWSSAGDGVHCFDPAGTLIGKIRVPQTVANLTFGGPRRNRLFITATASLYSIYLAISGSQRP
>NZ_CP015738.1|WP_064333459.1|189447_190398_+|ABC-transporter-permease
MTLFRHLAQKSWIWSWIAAVIVWLATISVTGGASAIGLTQAALTFAAFSIIVGIGQMFVITLGPGNIDLSVPATMTLAGTVALKLMNVENGMILPGLVVAILIGVAVGIGNYALIKTLRIPPIIATLSMSFIVQSTAIWTNRGLRIKPPPFLADFTTASTFGVPNVALIALVLSLVAWLLLEKTLYGRWISAIGQSMPAARMAGIPVDGARFVTYVFCAVLAALAGYLLACFSGGAALNMGSEYLLMSIAVVVIGGTAVAGGDSNVPGVWGASLFMFLVVSMLNTYGLGAGVRLIMTGLIIISVIMLAGGRRPGAR
>NZ_CP015738.1|WP_064333458.1|188509_189451_+|ABC-transporter-permease
MRMSNDAVRLLIPALSLTVLLAAVFWLQPRAMSYVGLNLLFNLAVPIALATIAQMLVMAVNDLDLSMGAFVSFVACVTATFLRDAPLVGGLILLGAIGVYALLGVVIHLRNLPSIVVTLGMSFVWAGLAVLLLPAPGGQAPDWARALMTMKPPVVPMAIVASIVIAAIAHLVVMRSSLGVLMRGVGGNQRSVERAGWSVILARAAAYGLAGLFAVLAGIALVGLTTSADANIALRYTLLSIAGVILGGGEFIGGRVSPIGAVIGALTLTLAGSFLSFLRISPDWQIGAQGAILITVLALRLVLNRIENRERRR
>NZ_CP015738.1|WP_064333457.1|187055_188513_+|sugar-ABC-transporter-ATP-binding-protein
MTGEMGKPVIAVAEARVSFGAVRALDGVTLSIMPGECVGLVGHNGAGKSTIVSVINGGLTPHAGGVAGDDGAPARAYGITAARARGVRCVFQELSLCPNLTIVENVRLMHRPLGGFGWRRRARAVIEASLAAIFPGHGIESDRTVGELSIAERQMVEIAMAFSDAGVAPRLVILDEPTSSLDASLAEQMLVHVRRFVAAGGSVVFISHILGEILATADRIVVMKDGRIVASRPAADFSERSLVEAMGSVVKGEAHRRASRDLTGAPVVLEQGGRGLPFLARAGEIVGLAGLAGHGQTDMLMALHAAGSGAWLPARDPAVTFVAGDRRLNGVFELWSILRNLSIASLGDMTRSGLVRTGEEDARGAEWQRRIEIRTPDMGNRILSLSGGNQQKVLFARALATRAPVVLMDDPMRGVDVGTKQEVYEIVRQEAATGRTFVWYSTEMEEVCLCDRVYVFREGRIVAELSGDAVGEANILAASFEGAAA
>NZ_CP015738.1|WP_064333456.1|185974_186991_+|ABC-transporter-substrate-binding-protein
MGIRKMLLASAVAACVAVPVSAFADTSGKKIALSNNYAGNSWRQAMLTSWDKVTGEAVKAGAVAAADPFTTAENQATEQAAQIQNMILQGYDAIVVNAASPTALNGAVKEACDAGITVVSFDGIVTEPCAWRIAVDFKEMGRSQVEYLSGKLPEGGNLLEIRGLAGVFVDDEISAGIHEGVKQFPQFKVVGSVHGDWAQDVAQKAVAGILPSLPEIVGVVTQGGDGYGAAQAIAAAKRPMPVIVMGNREDELKWWKEQKDANGYETMSVSIAPGVSTLAFWVAQQILDGKEVKKDLVVPFLRIDQDNLEANLATTQAGGVANVEYSQADAIKVIEAAQ
>NZ_CP015738.1|WP_145926064.1|184459_185896_-|sensor-histidine-kinase
MRENGRPVQARLGKSFAGFAREVAGSRKTRLCLSALTGGRRRRGRPPPGGCSPMLQLAPAALFEHYLGISRLLAGQLDFRSAIRSVANEVAHIIPHDHLDVCVLVEDGNYHTAYETGIDTAWGDLEGAPVVYSPIRSLLWGEVDYLLSDDATVDPRFRFEGAFRAPIDEQSLRSRIHVPMKVEGAIIAALSCSSQSAGLYTLDDVERARVIADLLTPYFFALRAAEQAQRSAIVEAEARAREEGLRLGALRLTEALEQERQRIGMDLHDQTLADLTRLARRVEQLSLSGEIGPDALEPVSRSLQHCMHDLRQIIEQAKPSVLQLFGLAQAVENHLDRSVRDSGMPIRWALADETAGALDKLEPTVSVALFRIAQEAINNAVRHARPTTLAVRLRIEAESLVLDVVDDGCGVVRTRGRIGSGVENMKTRARLISASCAIGAGRNNSGTTVTVRLPLAPQGGAAAPCEGGTGDESPDRGG
>NZ_CP015738.1|WP_064333454.1|183762_184485_-|response-regulator-transcription-factor
MKVLIVEDDPLHRSYLHEAVSAALPECETVIEAENGLSGEKLARDHKSAHIVMDLQMATRNGIEAARTIWKERPETRILFWSNYSDEAYVRGVSRIVPDGAAYGYVLKSASDERLKLALRSIFVESQCVIDREIRGVQQKSLGQTNGFTDSEYEILVDIALGLTDRAIARRRNLSLRSVQNRLQQLYDKLDVYQSTGEDSEDARFNLRTRAVTTALLRKLLNYSALEKAEADLQEWLTNL
>NZ_CP015738.1|WP_064333453.1|182841_183732_+|polysaccharide-deacetylase
MIKNPIPWPNGAKCAACITFDMDADSLIHIAHPEDGHSRVAGISMLQYGPKVAIPRIVESYRQLGIRQTFFVPAWCIERYPQAIEAILEGGHELAHHGFLHEHPRELSDEDEAYWLDRGIEVIVKASGRRPRGWRAPLYNFSHRSADLLVARGFEYDASLMGDDIPYLLECEAGSLVELPSHWGLDDWPQYVQSIDLDYMMPVRAPEQGFAAFAQEFEAAWRHGALWVPVVHPFATGRLARWEVVHRFLEQVLTRGDVWFAPMEEIAAHVRAVVDKGLWSPRIDRLPYYAEPVRVR
>NZ_CP015738.1|WP_064333452.1|182107_182845_+|SDR-family-oxidoreductase
MSRRVLITGAYRGIGAACALVFAATGARVALADIRRPDETAAAAAGAGAAETLALSCDVSDESAVLAVGDAVKERFGGLDVVVHCAGVIHEAPLLDTSAADFDRVIAINLRGSFLVGKMAIGLMEGTAEAPARVILIASDMAYYGRETFSPYVASKHGVLGLTRSWAKEFAPRILVNAICPGPIDTDMLGAANMSAEWRARELAIPLARFGQPEEIGELALFLAGSGGRYFTGQGVGSNGGSIMP
>NZ_CP015738.1|WP_145926065.1|194076_194364_-|hypothetical-protein
MRKGRIARHVRRNSLSIMGVSVAARAAASRKGRSCGASWLLPRIMKDGAERGPAEGERTLLPGHAAKDGKSFARSQPRALRFRVLDRTPLPIAKR
>NZ_CP015738.1|WP_064333463.1|194471_195335_+|transketolase
MARDDDLLSGEQLAFLEERARFVRLETLRLISIAKVGHYTSVFSCAEIFAALYYDVMRLRRGEPAWVDRDRFLMGKGHAAVGLFPILADLGFFDPAWLESYTRLGSPLGDHPDMTKVPGVDFSSGSIGHALSNGVGMLLGARFQKRDFNAFVLLGDGEMQEGQVWEAALSAAAHDLSNLVAIVDRNGYQLDGKVDDVMAIEPLDEKWRAFGWEVHTVDGHDLAALTTLLRRVKADRTREKPCCIIARTVKGKGIDYMETEPGWHLGYLGAEDEARARETILNTVISQ
>NZ_CP015738.1|WP_064333464.1|195331_196309_+|transketolase
MTQLLSKDSWQYREINRRAPSLPTLSNALIALAEAGHPVMAGTADLQYSNGLSGFAQRYPERFVQFGISEQNMVSAAAGMATTGVIPYVATFASFLALLCCEQIRMDVAYCRQPVRLIGHHTGISLGFYGTSHHATEDIAIMRSIANLAVVSTADGPALDAALRATVDYPLPIYFRIHRGHDPVVYENGVPFELGKAIVHGIGRDITIIAAGYPVHGARRAMEELNAAGHSVGLIDMHSIKPLDEEAIIEASARSKVILTVEEHTILGGLGGAVAEVLAEKGRGARLVRHGIRDEYSLIAPPTHLYRHYRLDGDGIRAVALESLA
>NZ_CP015738.1|WP_064333465.1|196320_197622_+|aspartate-aminotransferase-family-protein
MSTNNETIAARAESVIPGGLLSPSRRLGAPIAFARAEGAYLYDADGNRYTDYHCAFGANVLGHRPPAVAAAIAETAENLDLIGAGVLELEVEVAELLVNAIPCAEQVAFCSSGSEATYHALRLARAYTGRKQIIKFQGGYHGWHDYVAMNGQSSRQMIGSYDPMSDGMLFDAARHTAILPYNDAGAVEDYIRKNPGEVAAIIVEPIAHNMGAVIAEKQFLADLRRITSEHGVVLIFDEVITGFRHALGGYQSIVGVTPDLATFGKAATSGYPIGILAGRREIMERVGRTGEGAVFMGGTFNGTPASMAAVKATIGELARPGVYERLFELGAYLRGEIDGIIARHGLKAQAAGFGSVWLVYFFDGAFRDYTDLLRNDNDLDMRFRRALIAGRQVFQPLQLKRLYLSLSHDRAVLDDTLELIDTTMAGLARSVAA
>NZ_CP015738.1|WP_064333466.1|197658_198687_+|extracellular-solute-binding-protein
MRTRFFAMMASAALVVSSPALARDLTVVGFGGATQDVMRETLFKPYQDKAGTPLLEESYTGGIAKVKAMVETGTTTWDVVQMDENEMILACDQGLLEPFDWASLPNSADIIAPAKSDCGVGAFVWSKILAYDGDKTSGVTSWADFWNLDKWPGKRGLRKQARMTLEIALLADGAKPEELYDILATREGQDRAFAKLDEIKPSIQWWESGAQPMEWLASGEVTMTSAYNGRVIAANQQGRHFRMSWTHQLYAMDFWAIPKGGNRDQAFDIVNFMTSPEPQKAFAEKMVYGVTNAKAMDSIAADIKPQLPTAEENMAGALAVSTPFWVDHEEELQQRFNRWVAQ
>NZ_CP015738.1|WP_064333467.1|198698_199745_+|ABC-transporter-substrate-binding-protein
MTYRRFFGGLGMLAVLAGAPAAFADAGRLTVVGAGGVLQDAERKAFFEPFAAASGVVLTEDSYSGQMAKVRAMVDSGSVSWDVMQVEQNTLLSGCAEGLFEELDWSRIGKREDFIPEAYSDCGVGAFVWSMVPSYDKAKLADGPKTWADLWNVEKWPGKRGFRQTAKMTLEIALLSDGVAKDAVYDVLATDEGQDRAFAKLDEIKSSILWWTTGAESVERLAAGDVVATATFNGRVAAANASGKDFALIWDGQVFGIDYWGIVKGSPNRENAEKFIAFASTESAQAAFPQHIAYGVTNLAAIRGVKPEIAKDLPTTEANMAAAVALDTEFWADHGEALEARFATWRAQ
>NZ_CP015738.1|WP_064333468.1|199729_201016_+|ABC-transporter-permease
MARAMTSDVLLRPRAGAADGQQGRVSALAAGFRADRRRQTIVSLVLIGPLVAFIVFAFVLPLGTMLFHAINNPEVRNALPMTLASLEGWDGVDTPPDAAFEALAADIRAGADPKVLAEAGRRLNYEITGFRSLLAKTVRTVRKAPVEPARAQLLAIDGNWDNPAYWRVIQRNGAPLTAFYLLSAVDLRPGENGGVQMAPPEERLFLSTLMRTLTISALVTVICLFVAYPVANAIVAIGGRFSAIMLACVLLPFWTSLLVRTSAWIVILQKEGVVNRLLQALNITDAPLELVFNRTGLYIAMVHILLPFMVLPLVSVMKGISPSYVKASASLGAGPVTTFLRVYLPLTLPGVGAGCLLTFIISAGYYVTPTLVGGASDQMLSYFVAFYANTTINWGMSAALGVLLLACILALYGIVGRIVGIGRIVGME
>NZ_CP015738.1|WP_064333469.1|201019_201823_+|ABC-transporter-permease
MPVALRRVQIAFCCLAMVFLIGPTLVIIPISFSSANFLSYPLPGFSLQWYEKILQPQPWMSALLNSLIIGVGATLVSTVLGTLAALGMSRGRLPARSMILAVVISPMIVPVVISGVGMYFFFARLGLVASFLGLVLAHAVLAVPFVLITVTATLKNFDMNLVRAAASLGASPFHAFRTVTLPLIAPGVISGALFAFVFSFDEVVVALFISGPGQRTLPRQMFDGLRDNIDPSILAMSTLLVIISIVLMGGGALAQKRAAANRSIANL
>NZ_CP015738.1|WP_064333470.1|201833_202577_+|SDR-family-oxidoreductase
MIIVTGATHGIGRACVEKLAAAGARVVATGRDAAAGRALEEIGPGVTFVPGDVGREEDCRRVVDRALDLGGGRLAGLVNNAGMSKRISFAAATQDDWDEVLAVNARSTFLFIRHALEGLRRGRGSVVNIASIAGKTGEEGLAVYCASKAAVIGLTQALALEFGEEVRFNAVCPGQIGTRMMDRIMSDALRRKQLELRIPANRFGAPQEVADVVAWLLSDQSTYVNGTVVTVDGGETAGLRTPRIAQV
>NZ_CP015738.1|WP_064333471.1|202596_203274_-|GntR-family-transcriptional-regulator
MSVMEMQPGEVGSLSARIYTKVREGLIVGNFAPGDRLLMQDLAEQLGTSVTPVREACLRLVSEQALELRSGRFVTVPDLSRARYIQIKLIRMALEGLAAEHAADHVTAADLAQLEAFHAAFVKNEKAGNLEAARSSNRAFHFGVYRLSRMPMLVGQIESMWVSMGPILNVYYREIPHNYTGAEEHVHLIEALRAGDKKKARQAIENDIQRASPSLLRYFEERGAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015738_1	1.1\|193352\|31\|NZ_CP015738\|CRISPRCasFinder	193352-193382	31	NZ_CP015738	Shinella sp. HZN7 plasmid pShin-02, complete sequence	193352-193382	0	1.0
NZ_CP015738_2	2.1\|193556\|31\|NZ_CP015738\|CRISPRCasFinder	193556-193586	31	NZ_CP015738	Shinella sp. HZN7 plasmid pShin-02, complete sequence	193556-193586	0	1.0
NZ_CP015738_1	1.1\|193352\|31\|NZ_CP015738\|CRISPRCasFinder	193352-193382	31	NC_020548	Azoarcus sp. KH32C plasmid pAZKH, complete sequence	499114-499144	7	0.774
NZ_CP015738_2	2.1\|193556\|31\|NZ_CP015738\|CRISPRCasFinder	193556-193586	31	NC_015963	UNVERIFIED_ORG: Enterobacter soli plasmid pENTAS01, complete sequence	124220-124250	9	0.71

1. spacer 1.1|193352|31|NZ_CP015738|CRISPRCasFinder matches to NZ_CP015738 (Shinella sp. HZN7 plasmid pShin-02, complete sequence) position: , mismatch: 0, identity: 1.0

gtatggtcgcgacacgatgagtggcggcaat	CRISPR spacer
gtatggtcgcgacacgatgagtggcggcaat	Protospacer
*******************************

2. spacer 2.1|193556|31|NZ_CP015738|CRISPRCasFinder matches to NZ_CP015738 (Shinella sp. HZN7 plasmid pShin-02, complete sequence) position: , mismatch: 0, identity: 1.0

caacggcaacgatcgcatgtggggccagggc	CRISPR spacer
caacggcaacgatcgcatgtggggccagggc	Protospacer
*******************************

3. spacer 1.1|193352|31|NZ_CP015738|CRISPRCasFinder matches to NC_020548 (Azoarcus sp. KH32C plasmid pAZKH, complete sequence) position: , mismatch: 7, identity: 0.774

gtatggtcgcgacacgatgagtggcggcaat	CRISPR spacer
ccagggccgcgacacgatcagtggcggccac	Protospacer
 .* **.*********** ********* *.

4. spacer 2.1|193556|31|NZ_CP015738|CRISPRCasFinder matches to NC_015963 (UNVERIFIED_ORG: Enterobacter soli plasmid pENTAS01, complete sequence) position: , mismatch: 9, identity: 0.71

caacggcaacgatcgcatgtggggccagggc	CRISPR spacer
aacaagcaatgagcgcatgtggggccagaag	Protospacer
 *  .****.** ***************..

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP015745

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

50939 : 107011

Lactococcus_phage(23.08%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_064334688.1\|50939_52436_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_064334689.1\|52432_53191_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	8.4e-42	39.7
WP_064334693.1\|59316_59883_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_064334694.1\|60241_60934_+	hypothetical protein	NA	NA	NA	NA
WP_064334695.1\|60936_62607_+	hypothetical protein	A0A0P0CRP3	Ostreococcus_lucimarinus_virus	8.9e-36	27.9
WP_145926147.1\|63521_64061_+\|transposase	transposase	NA	NA	NA	NA
WP_064334696.1\|64441_64621_+	hypothetical protein	NA	NA	NA	NA
WP_064334697.1\|64613_66680_+	recombinase family protein	A0A1B2LRQ3	Wolbachia_phage	1.3e-07	25.4
WP_084438738.1\|66986_68543_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_064334699.1\|68523_69684_-	HlyD family secretion protein	NA	NA	NA	NA
WP_064334700.1\|69676_70132_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_064334458.1\|70438_71032_-	recombinase family protein	A0A219Y912	Aeromonas_phage	2.9e-21	34.6
WP_064334459.1\|71186_74162_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	2.0e-187	37.7
WP_064334701.1\|74801_75461_+	HNH endonuclease	NA	NA	NA	NA
WP_064334702.1\|76136_77351_-	replication initiation protein RepC	L7TKN6	Rhizobium_phage	2.1e-18	28.2
WP_064334703.1\|77506_78529_-	plasmid partitioning protein RepB	A0A240F4U0	Ochrobactrum_phage	3.1e-47	36.4
WP_064334742.1\|78525_79740_-	plasmid partitioning protein RepA	A0A240F4U1	Ochrobactrum_phage	1.2e-117	54.5
WP_064334704.1\|80128_80752_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_064334705.1\|80764_81742_+	P-type conjugative transfer ATPase TrbB	NA	NA	NA	NA
WP_064334706.1\|81731_82115_+	conjugal transfer protein TrbC	NA	NA	NA	NA
WP_064334707.1\|82107_82407_+	conjugal transfer protein TrbD	NA	NA	NA	NA
WP_064334708.1\|82416_84873_+	VirB4 family type IV secretion/conjugal transfer ATPase	NA	NA	NA	NA
WP_064334709.1\|84844_85648_+	P-type conjugative transfer protein TrbJ	NA	NA	NA	NA
WP_064334710.1\|85641_85818_+	entry exclusion protein TrbK	NA	NA	NA	NA
WP_064334711.1\|85822_87001_+	P-type conjugative transfer protein TrbL	NA	NA	NA	NA
WP_064334712.1\|87025_87688_+	conjugal transfer protein TrbF	NA	NA	NA	NA
WP_064334713.1\|87705_88518_+	P-type conjugative transfer protein TrbG	NA	NA	NA	NA
WP_064334714.1\|88521_88959_+	conjugal transfer protein TrbH	NA	NA	NA	NA
WP_064328977.1\|89889_90648_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.9e-42	40.5
WP_064328978.1\|90644_92141_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.1e-13	25.2
WP_064334717.1\|93554_94652_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_064334718.1\|94980_95409_+	hypothetical protein	NA	NA	NA	NA
WP_084438739.1\|95457_96261_+	DUF1403 family protein	NA	NA	NA	NA
WP_064334719.1\|96601_97627_-	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	1.4e-39	32.2
WP_064334720.1\|97638_98550_-	acetaldehyde dehydrogenase (acetylating)	E5EQ71	Micromonas_sp._RCC1109_virus	9.8e-37	35.1
WP_064334721.1\|98566_99850_-	TRAP transporter large permease	NA	NA	NA	NA
WP_064334722.1\|100445_101453_-	DctP family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_064334723.1\|101669_103067_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_064334724.1\|103113_103893_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_064334689.1\|104759_105518_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	8.4e-42	39.7
WP_064334688.1\|105514_107011_-\|transposase	IS21 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP015742

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

71372 : 134019

Salmonella_phage(15.38%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_145926128.1\|71372_71627_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-14	52.8
WP_064334419.1\|71751_73950_-	xanthine dehydrogenase family protein molybdopterin-binding subunit	NA	NA	NA	NA
WP_064334420.1\|73954_74905_-	xanthine dehydrogenase family protein subunit M	NA	NA	NA	NA
WP_064334421.1\|74901_75534_-	aldehyde dehydrogenase iron-sulfur subunit	A0A0P0IVM8	Acinetobacter_phage	2.2e-19	35.8
WP_064334422.1\|75601_76096_-	DUF305 domain-containing protein	A0A1V0SJW0	Klosneuvirus	4.1e-05	30.2
WP_064334423.1\|76409_78023_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	3.2e-22	25.4
WP_064334424.1\|78271_78874_+	hypothetical protein	NA	NA	NA	NA
WP_064334425.1\|78851_79859_+	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_064334426.1\|80231_81686_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_084438697.1\|81996_82449_-	response regulator	NA	NA	NA	NA
WP_064334427.1\|82687_83323_-	DUF1109 family protein	NA	NA	NA	NA
WP_064334428.1\|83324_83879_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_064334429.1\|84105_84387_+	DUF2282 domain-containing protein	NA	NA	NA	NA
WP_064334430.1\|84452_85307_+	DUF692 domain-containing protein	NA	NA	NA	NA
WP_064334431.1\|85310_86087_+	DUF2063 domain-containing protein	NA	NA	NA	NA
WP_145926129.1\|86058_86532_+	DoxX family membrane protein	NA	NA	NA	NA
WP_064334433.1\|86755_88123_+	chloride channel protein	NA	NA	NA	NA
WP_064334434.1\|88285_89770_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.1e-169	65.9
WP_064334435.1\|90090_90351_+	DUF4212 domain-containing protein	NA	NA	NA	NA
WP_064334436.1\|90360_92127_+	cation acetate symporter	NA	NA	NA	NA
WP_064334437.1\|92208_94035_+	CBS domain-containing protein	NA	NA	NA	NA
WP_064334438.1\|94046_94577_+	hypothetical protein	NA	NA	NA	NA
WP_064334439.1\|94580_96266_+	3'-5' exonuclease	A0A1X9SH08	Bradyrhizobium_phage	3.2e-17	36.5
WP_064334440.1\|96722_97679_+	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_064334441.1\|97756_99862_+	TRAP transporter permease	NA	NA	NA	NA
WP_064334442.1\|99858_100257_+	DUF1850 domain-containing protein	NA	NA	NA	NA
WP_064334443.1\|100343_102158_+	sensor histidine kinase	NA	NA	NA	NA
WP_064334444.1\|102154_103516_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_064334445.1\|103576_104860_+	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_064334476.1\|104950_106108_+	osmoprotectant NAGGN system M42 family peptidase	NA	NA	NA	NA
WP_064334446.1\|106208_107786_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_064334447.1\|107816_108764_+	ABC transporter permease	NA	NA	NA	NA
WP_064334448.1\|108792_110550_+	dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein	G9BWD6	Planktothrix_phage	2.3e-26	31.8
WP_064334449.1\|110546_111344_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.4e-15	30.3
WP_064334450.1\|111340_112123_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_064334451.1\|112243_114019_+	N-acetylglutaminylglutamine amidotransferase	F2Y1H0	Organic_Lake_phycodnavirus	2.4e-31	26.6
WP_064334452.1\|114020_115808_+	N-acetylglutaminylglutamine synthetase	NA	NA	NA	NA
WP_064334477.1\|115814_118022_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_145926130.1\|118160_118475_+	hypothetical protein	NA	NA	NA	NA
WP_064334453.1\|118734_119634_-	hypothetical protein	NA	NA	NA	NA
WP_084438707.1\|121578_121848_-	hypothetical protein	NA	NA	NA	NA
WP_145926060.1\|122057_123270_+\|transposase	IS3 family transposase	A0A1B0Z042	Pseudomonas_phage	1.2e-66	48.8
WP_145926131.1\|124327_124453_+	hypothetical protein	NA	NA	NA	NA
WP_084438708.1\|124662_125214_-	TOBE domain-containing protein	NA	NA	NA	NA
WP_145925838.1\|125638_126858_-\|transposase	IS3 family transposase	A0A1B0Z042	Pseudomonas_phage	2.2e-76	53.9
WP_050746605.1\|126934_127963_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_064334456.1\|128104_129661_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_064334457.1\|130127_130316_+	hypothetical protein	NA	NA	NA	NA
WP_064334458.1\|130295_130889_-	recombinase family protein	A0A219Y912	Aeromonas_phage	2.9e-21	34.6
WP_064334459.1\|131043_134019_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	2.0e-187	37.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP015743

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

113907 : 125379

Stx2-converting_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050746970.1\|113907_115263_+	MBL fold metallo-hydrolase	Q331V3	Clostridium_botulinum_C_phage	4.7e-19	30.3
WP_082342933.1\|115304_116777_+	thymidine phosphorylase family protein	A0A0H3UZD4	Geobacillus_virus	1.9e-21	25.4
WP_064334523.1\|117343_117766_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_050746938.1\|117762_118107_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.7e-32	56.6
WP_050746941.1\|118154_119807_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.9e-91	42.1
WP_050746939.1\|119809_120394_+	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	2.5e-17	31.6
WP_168169015.1\|120401_120701_-	hypothetical protein	NA	NA	NA	NA
WP_050746940.1\|120747_121629_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	6.1e-52	46.3
WP_050746942.1\|121625_122885_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.0e-44	36.6
WP_084438720.1\|123231_123780_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_050747148.1\|124038_125379_-\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	1.1e-31	28.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_CP015736

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015736_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015736_1

972268-973293

orTypeII

Consensus_repeat	Method
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CRISPRCasFinder
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CRT
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	PILER-CR

15 spacers

cas2,cas1,cas9

The CRISPR arrays of NZ_CP015736_1

>merge|NZ_CP015736|1|972268-973293|CRISPRCasFinder,CRT,PILER-CR
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACCAACTCGCCTTCGAGCGCCTGGATACGGCGAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACTTCGGATGCCGCCCCGTGGCGGGGCGGTCAAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACTCCCCGCCACAAGCACGGACACGGGCGGGGAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACATGCTGGCGCGTGCGTATTCGAGCAGCGGGAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACGGTGGAAAGGCTGAACATGCTGTCTCCTAAAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACACTTCGCTCTGAAGGTTCGCCTGAGACTGCAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACAAGGACGGGGGCCTCCTCGGCGGCGAAATCAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACCGGGCGAGCGAGCAATCGCTGCGGCCCTCGAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACGGTTCCACCATCGCCAATAGGCTGGCCCTTAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACTGTCAGATCGAGGAAAAGGGCTTTGTTTACAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACAAGGTGAACGTCACTGGGACGCGCAACTGGAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACCGGGTTTTCATTGATAGTCTCTCCTGGTGCAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACAACAATGAGGGCGCGGCCTTCTGGGAGCACAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACAAAATGAGTACCGTCGAGTTCTGCCAAAATAGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAACGACGATCTCGCGCAGGGGCGTGTCGGCCGGAGCCAAGCAGTTCAGAAATCGCAGGCCAACCGCAAC

>NZ_CP015736|1|1|972268-973293|CRISPRCasFinder
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CAACTCGCCTTCGAGCGCCTGGATACGGCG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	TTCGGATGCCGCCCCGTGGCGGGGCGGTCA
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	TCCCCGCCACAAGCACGGACACGGGCGGGG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	ATGCTGGCGCGTGCGTATTCGAGCAGCGGG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	GGTGGAAAGGCTGAACATGCTGTCTCCTAA
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	ACTTCGCTCTGAAGGTTCGCCTGAGACTGC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AAGGACGGGGGCCTCCTCGGCGGCGAAATC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CGGGCGAGCGAGCAATCGCTGCGGCCCTCG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	GGTTCCACCATCGCCAATAGGCTGGCCCTT
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	TGTCAGATCGAGGAAAAGGGCTTTGTTTAC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AAGGTGAACGTCACTGGGACGCGCAACTGG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CGGGTTTTCATTGATAGTCTCTCCTGGTGC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AACAATGAGGGCGCGGCCTTCTGGGAGCAC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AAAATGAGTACCGTCGAGTTCTGCCAAAAT
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	GACGATCTCGCGCAGGGGCGTGTCGGCCGG
AGCCAAGCAGTTCAGAAATCGCAGGCCAACCGCAAC

>NZ_CP015736|1|1|972268-973293|CRT
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CAACTCGCCTTCGAGCGCCTGGATACGGCG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	TTCGGATGCCGCCCCGTGGCGGGGCGGTCA
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	TCCCCGCCACAAGCACGGACACGGGCGGGG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	ATGCTGGCGCGTGCGTATTCGAGCAGCGGG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	GGTGGAAAGGCTGAACATGCTGTCTCCTAA
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	ACTTCGCTCTGAAGGTTCGCCTGAGACTGC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AAGGACGGGGGCCTCCTCGGCGGCGAAATC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CGGGCGAGCGAGCAATCGCTGCGGCCCTCG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	GGTTCCACCATCGCCAATAGGCTGGCCCTT
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	TGTCAGATCGAGGAAAAGGGCTTTGTTTAC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AAGGTGAACGTCACTGGGACGCGCAACTGG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CGGGTTTTCATTGATAGTCTCTCCTGGTGC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AACAATGAGGGCGCGGCCTTCTGGGAGCAC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AAAATGAGTACCGTCGAGTTCTGCCAAAAT
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	GACGATCTCGCGCAGGGGCGTGTCGGCCGG
AGCCAAGCAGTTCAGAAATCGCAGGCCAACCGCAAC

>NZ_CP015736|1|1|972862-973293|PILER-CR
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	TGTCAGATCGAGGAAAAGGGCTTTGTTTAC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AAGGTGAACGTCACTGGGACGCGCAACTGG
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	CGGGTTTTCATTGATAGTCTCTCCTGGTGC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AACAATGAGGGCGCGGCCTTCTGGGAGCAC
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	AAAATGAGTACCGTCGAGTTCTGCCAAAAT
AGCCTAGCAGTTCAGAAATCGCAGGCCAACCGCAAC	GACGATCTCGCGCAGGGGCGTGTCGGCCGG
AGCCAAGCAGTTCAGAAATCGCAGGCCAACCGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015736.1\|WP_064329365.1\|958050_958932_+\|protein-deglycase-HchA	unknown	unknown	gnl\|CDD\|235228
NZ_CP015736.1\|WP_064332441.1\|978979_980113_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173797
NZ_CP015736.1\|WP_064329370.1\|974948_975665_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015736.1\|WP_064329366.1\|958938_959649_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|132580
NZ_CP015736.1\|WP_064329372.1\|976036_976573_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226314
NZ_CP015736.1\|WP_064329364.1\|956475_957627_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP015736.1\|WP_064329373.1\|976574_977207_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP015736.1\|WP_064329375.1\|978074_978617_-\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP015736.1\|WP_064329362.1\|954158_955385_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270303
NZ_CP015736.1\|WP_168168878.1\|974159_974300_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015736.1\|WP_064329376.1\|980416_981223_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|182561
NZ_CP015736.1\|WP_064329369.1\|970897_971824_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP015736.1\|WP_064332439.1\|971889_972195_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP015736.1\|WP_064329371.1\|975750_976044_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015736.1\|WP_064329363.1\|955453_956476_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP015736.1\|WP_084437761.1\|960876_966867_-\|DUF3320-domain-containing-protein	unknown	unknown	gnl\|CDD\|379066
NZ_CP015736.1\|WP_084437764.1\|974411_974771_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370635
NZ_CP015736.1\|WP_064329367.1\|959675_960449_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181762
NZ_CP015736.1\|WP_064329368.1\|967538_970844_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|273840
NZ_CP015736.1\|WP_064329374.1\|977349_978078_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227949

Protein	Function_ID	Function_description	E-value
NZ_CP015736.1\|WP_064329365.1\|958050_958932_+\|protein-deglycase-HchA	gnl\|CDD\|235228	PRK04155, PRK04155, protein deglycase HchA.	0
NZ_CP015736.1\|WP_064332441.1\|978979_980113_+\|S8-family-serine-peptidase	gnl\|CDD\|173797	cd05561, Peptidases_S8_4, Peptidase S8 family domain, uncharacterized subfamily 4. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.0595e-81
NZ_CP015736.1\|WP_064329373.1\|976574_977207_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	2.03382e-12
NZ_CP015736.1\|WP_064329366.1\|958938_959649_+\|hypothetical-protein	gnl\|CDD\|132580	TIGR03541, reg_near_HchA, LuxR family transcriptional regulatory, chaperone HchA-associated. Members of this protein family belong to the LuxR transcriptional regulator family, and contain both autoinducer binding (pfam03472) and transcriptional regulator (pfam00196) domains. Members, however, occur only in a few members of the Gammaproteobacteria that have the chaperone/aminopeptidase HchA, and are always encoded by the adjacent gene.	1.94869e-123
NZ_CP015736.1\|WP_064329372.1\|976036_976573_-\|hypothetical-protein	gnl\|CDD\|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	0.000160744
NZ_CP015736.1\|WP_064329364.1\|956475_957627_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.05851e-47
NZ_CP015736.1\|WP_064329375.1\|978074_978617_-\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	2.70095e-39
NZ_CP015736.1\|WP_064329362.1\|954158_955385_+\|extracellular-solute-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2743e-24
NZ_CP015736.1\|WP_064329376.1\|980416_981223_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|182561	PRK10575, PRK10575, Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC.	1.69231e-113
NZ_CP015736.1\|WP_064329369.1\|970897_971824_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	5.77496e-81
NZ_CP015736.1\|WP_064332439.1\|971889_972195_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.10831e-17
NZ_CP015736.1\|WP_064329363.1\|955453_956476_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.05845e-34
NZ_CP015736.1\|WP_084437761.1\|960876_966867_-\|DUF3320-domain-containing-protein	gnl\|CDD\|379066	pfam13195, DUF4011, Protein of unknown function (DUF4011). This family of proteins is found in archaea and bacteria. Many members are annotated as being putative DNA helicase-related proteins.	3.66418e-57
NZ_CP015736.1\|WP_084437764.1\|974411_974771_-\|hypothetical-protein	gnl\|CDD\|370635	pfam09726, Macoilin, Macoilin family. The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.	0.000199273
NZ_CP015736.1\|WP_064329367.1\|959675_960449_+\|SDR-family-oxidoreductase	gnl\|CDD\|181762	PRK09291, PRK09291, SDR family oxidoreductase.	1.85061e-139
NZ_CP015736.1\|WP_064329368.1\|967538_970844_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|273840	TIGR01865, conserved_hypothetical_protein, CRISPR subtype II/NMENI RNA-guided endonuclease Cas9/Csn1. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.	9.10373e-76
NZ_CP015736.1\|WP_064329374.1\|977349_978078_-\|hypothetical-protein	gnl\|CDD\|227949	COG5662, COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription].	2.43752e-08

>NZ_CP015736.1|WP_064332439.1|971889_972195_+|CRISPR-associated-endonuclease-Cas2
MWMLVTFDLPVDTKRHRAEATKFRQFLLDQGFEMSQLSNYLRLVNGQEQFETYTRRIGSNLPERGDVFIFQFTDRQYENIVRFSDQSRRTRKKNPEQIALF
>NZ_CP015736.1|WP_064329369.1|970897_971824_+|type-II-CRISPR-associated-endonuclease-Cas1
MQRVVDLSSDGLHVAVHRGFLTVSKDREEMGRVALDDIGGVIAHAHGLTWSNTVFVRLSERAVPVVLCAANHAPIACVWPLQGNHLQGRRLNAQVDASRPLAKRIWRDIVVAKIRMQGAVLASVGAEAGAFDMLARKVRSGDPDNVEAQAARRYWQAFMGPDFRRDQDGEGINALLNYGYTVLRAIISRAICAAGLHPSIGLHHSNRANAFALADDLMEPYRPIIDRAVYNLVQDGLREVSPKAKTALVTLTALDLPAPHGMSPLHVHATRLAQQLAALFDKEDEGLELPSPLDPLTLSGLARQGGTP
>NZ_CP015736.1|WP_064329368.1|967538_970844_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKTLGLDLGTNSLGWAIVETRDEPTKYSEGSIVASGVRIFSQSEMAGRDPQSKASLAVARRQARGSRRRRDRYLKRRQRLVDLLVDLGLMPADKAARAELVKNHGDGKTGDLSSSVYALRARALDEALSPYEIGRAIFHLNQRRGFKSNRKADSNDPEQGVISEGMRALDEKMAEAGARTIGEWLHMRRLQGLPVRARIAPDGEGYAFYPSRGALEREFDRIMARQTLFHTDLLTDTAIRELREVVFHQRPLRPVKPGKCSYNPLEERLAKAHPLFQKFRLLKELNELEIVGEDQKHIKLTPEQRNALALQLRTSLTKQGKVPFSKLRSTLKLGREVRFNKETDNRSDLEGDVIYFRMSRPECFGNRWADLPVEMQAAITERLRTEPDYKTLMNWLKAETGLDEVHARAVADTPVPDGFGRLGQSALTALIDALENEVGEGGFVITEAEAAKRVYGRTNSEADPDRKGVDELPKYQEVLARHIPPGTGEPDDPYDDFMGRITNPTVHIALNQLRRVVNALIRTYGKPDRIAIEVGRDLKMNDRERDEVNRRIGRNTKAAIERGVKLTETFRQLDTGYNRLRLELWEDLNQKPENRVCIYCGKAIAGHMLFNGETDIDHILPYSKTLDDSKANRILCCTSCNREKKNRPPSRVPQWRSRYGEILARATTLPKNKQWRFAEDAMTRFGEEEGFLARQLTDMQYISRLALTYLAHLYDYEEVDLDGIYKRHARVRALPGRMTEMLRRQWGLNELLHDHNLIGGDVAKPKNRLDHRHHAIDAIVIACTSRALIQRLATASAAAEERGAERVVERIDPPWSGFREDVRAAVGAIVVSHKPDHGTVGREGYAKGRGQTAGKLHNDTAYGHTGEKDASGNDIVVRRIAVTDIRSPADIRKIRTNAHGHSELRDRLYEATRGLEGKAFEQAVLDFVKGDAKFRGIRHVRITEVANPVWITHGDGRHKKGYLPGGNDRFDVWELADGRWDAEVVTTFDAHRPGFVPRMRLENHNARKIMSLKKGDMIAYNDPVSGQRIIAIVRKFDQRNKQLYLDPHNEAGNLDRREKEKTYKPLRPMPNPLKKYRPRQVRIDEIGQVFDPGPWWERQDG
>NZ_CP015736.1|WP_084437761.1|960876_966867_-|DUF3320-domain-containing-protein
MQMAEDNSPEQYDAGISNTRERPVVVADIAASFTYASYQNAIPVIRSILIENNSDRHFANCKLELTSSPSFLRPKTWTIDRLVPGDRLALSDRKVELDASYLAGLNEAERGEITLRLSSAGNVLDERHLPVRLLARDEWGGVADMAQLLPAFVMPNDPGVAPILRTAAERLAAHGYPSGLDGYQSESPQRAYLLAAAIYSAIAGMALHYAEPPASFESRGQKIRRPSTIAEERLATCLDTTLLFAAALEAAGLYPVLLMFQGHASAGVWLARRTLANAIETDQMEVRKALASRELIVFETTGVTHRPAMTMENAQRILDNRLSEKEAHAFVAAIDVRRSRSGGIMPLASHEPIRRAVPDEEMAPVADLPLPAAPSFGELPVETIEVKPTTAAGRIDRWQKKLLDLTLRNRLLNFPDSRKTIPFLCTDVAYLEDRLAGGGAIRIISLPEQNPLGERDAALYRDVHGKDLQRGFAAEALLRDELPSTLGASELEARLIDLYRQVRNDFAEGGANTLFLAVGFLRWKKKPEDDRSYRAPLLLVPVKLERRSASSRFTVRFHEDEPRFNATLLQFLERDFDLTLPQFAGDLPLDDNGIDVPRLLAMMRQAIRDVPGMEVVDETALSTFSFAKFLMWKDLVERTEALRANKVVRHLIDTPEQAFQAGDGQPSFREERELDRAYAPSDLICLLPSDSSQMAASLAAAEGRDFVIVGPPGTGKSQTIANMIANCLAVGKTVLFVAEKTAALDVVYRRLREHGLANHCIELHSNKADRRHFLGQLKAAWEQGGGIDASEWVAVNERLRLRRDELNAYVEALHKRYPNGWTPYLALGIALKAAENPAPGLAWPERDAHDAQTLQDLEELAGELGLVFASVERQPVLDLVDVGDWSSGWQESLLAAAQSLKDAAEAVRTAVEAYLASLGLGSQGRSSQAEIQGLTNLARVVRKCRGRDITIAFDRELPQCAGALETLANSIKSYREAERGLSAAYAVTAVRDLDPDALDRQWREANASFWPTSALGKRKVQKLLQGYADGGTAEPERDIPLLRRMKECLSAIDRNQLTGKPLPIDGLATDVVAITEILELAWEFRATVPIPGRGQEETRSMLRSVAPCLRGTFENDRVRQTGDRLLTAIEGLQAARQRFREIAGREISAGSDGPDLVTLSEDIGALVNARHLLRDWSAWCRIRRRAMASSLAPLVEQIEKGVVRPEEARSAFRLGYARWWLPKVLDSDPVLRDFRRFQHENAIKEFREIDDLVRSHATRRVISAIAHGLPAVQSVSRNSELGLLRHQMELQRPSQSIRDMIGKMPQSFPKLAPCMLMSPLSIAQYLPPDQALFDVVIFDEASQITTWDAVGAIARARQTVIVGDPKQLPPTNFFGRNEDEDEIADHEKDLESILDEAKAAGIPVRDLRWHYRSRSESLIAFSNHHYYQNRLVTFPSPLVEDRAVRLHKVPDGVYDRGKSRTNRIEAEAVTREAVCRMKGWLRLPEKDRPTLGIITFNAQQQSLILDLLDTARRDDPELEWFFAEERVEQTIVKNLENVQGDERDVIFFSITFWKDAAGKLTMDFGALNRDGGERRLNVAVTRARQELVVFSGFTADQIDPARTKALAVQHLKTFLDYAERGAIALPAQDIGSVGGFDSPFEEAVAAQLERRGWTVVPQVGISGFRIDLGVRHPDLAGAYLAGVECDGATYHRSATARDRDKVREQVLKGLGWNILRVWSTDWWFDAAGCVERLHAGLESLLEESRARRAAEKEDVATHWDMGHEVEGIEEIRDDGVVPAEEIAPPPATTETELVSAEAPMVSRGIEGAAMQAPASATVVGIVEKRRYHVTDLSGFPADPDQFFEFGYRDILRRMIEAIIETESPLRTDILAQRLARAHGWLRTGGRIRERIDLHLRDLDRTVESSGEFIWKKGTVSDILPYRQPASEDARRSIGDIPLAELTAVVLDNPDLLDEPDPARDLARLLGVERLAGVSRARLDEALAKARQHAANIRPSA
>NZ_CP015736.1|WP_064329367.1|959675_960449_+|SDR-family-oxidoreductase
MAKTVLVTGAASGFGRGVALGLASRGHNVIAGCQIWPQVTELRNAAAAEGVGMQVIKLDVLSEIDRKNALEREIDVLFNNAGIMESGPMVEIPMSVFRSVFETNVFAALELAQGFARSMVKRGSGRIVWTSSVAGLVKVPFDGAYAASKHAVEGVCSAMHEELKPYGVEVLTVNPGAFRTGFNDTGMESMDQWWNQGERVVEHWPVRELDRQHDPAEMIQAIIDVIEAEKPAYRTIRPASAEEMVRKEQAAVWERHA
>NZ_CP015736.1|WP_064329366.1|958938_959649_+|hypothetical-protein
MQADATFRVALDIECSQTPSAIEDVVRSFARPLGYDRFVLFSASAARDDVVERIYWVEGDWFGDGETVDAETYIRRCPVTRHMLETHDPFFWTKAREEGGERYRVVRMPRGRGIHGLQIPIFGPSGLEGAMSLGGEHIDASPPARLALAVVASAAFLAARRLLEAPADGVTGKLSNREREVLAWTAAGRRQSDIAATLDLSERTIENHLRRIRRRLGVATTAQAIKVAIRNGDIEG
>NZ_CP015736.1|WP_064329365.1|958050_958932_+|protein-deglycase-HchA
MANPQSDDKRPTPDPAEDNAFFPSPYSLSQFTSPKSDLSGANYSDPYTGGRWKILMIGADERYLLTDNGTMFSTGNHPVETLLPMYHLDKAGFSFDVATLSGNPVKFEFWAMPTEDEKVKGLFAKYRAQFKQPLKLADVIETALGEESDYIAVFIPGGHGALIGLPESEDVKTVLEWAAAKDKFVISLCHGPAAFLAVGLGDMKGGRSIYDGYKICAFPDDLDAQTPDIGYMPGHLTWKFGEKLKALGIEIVNQGISGATHQDRKMLTGDSPLAGNALGKLAAEALLKEAAAG
>NZ_CP015736.1|WP_064329364.1|956475_957627_+|carbohydrate-ABC-transporter-permease
MSTVKALRQPASLQIVSAGFLLFWCVLALFPIAWIAVMSIKAPLDAFAANPFDVILGPATIAQGSGLTLADIAAALLGGGLAIWFAIKVLPGLVARHVPPGYRLLGWILALIGYCIIVLLAGFILLPRLAQAVNAAMALDPVIGFTTQHYHAVWVENAFWQNFVNFAIVTTGVVTISLTVGTLAGYGLSRSGSNLAFWLLIGALVFRALPHSVLVAGYLPVFINSAELLRPLLGENAPTLYGQPLAVIIVLVSINQPFTIWMLRSFFQSIPAELDEAARVDGCTHFQAFRRVIMPVMWPGVITTGLFSFLLAYNDFLVTSLLLDQSDMTMVPAIAAYFNRETTTTDQVEAIAAAVSITAPLFLLVMAFQRQIVSGLTAGAVKG
>NZ_CP015736.1|WP_064329363.1|955453_956476_+|sugar-ABC-transporter-permease
MRFRTFAAFVAPSLLLMVLFIAAPLASVFVQSFFVTQPQIQRVETERCTAGFLEQQCTTEIKNVPVLDKNGAVVTTTRFVGLDNYRAVVRPDRAFAALSAWDWQALMSIDFWKALRFTLTFTLVTLPLVVGLGLAIALAVNNTMRSIRGPVIFVSLLPFIVTPVIGALSIRWLFVGDGILTRAMEAWSGTEIAMFAQGWTIELLMLFYRVWHVAPFAFVIFYAGLQTMNRETLEAAMVDGASRFERLRYVIVPHLMPLIVFVSLIHLMDAYRVFEEVVGFRSQAHVISLQWLTYDLLQPDDAGNRAVSRASASAMLTMIGIVILLVPLLRKSWRDHKGAR
>NZ_CP015736.1|WP_064329362.1|954158_955385_+|extracellular-solute-binding-protein
MKRRNLFIFAVLAALGSGPANAACSFSNEVPIKVLSAAFEAWKSVTDAMAECGNVQASLDQDFRLKQSAAFAANPALYQLGGVANNTIPQLLNEKRIRPLNDLVEKYGQHLKPNQLIKVGGDIVAIAMMVNTQEFAYRKDIFDELGLDVPKTYDQVFEAAEKIRQSGKVDYPLGGMTMSGWNMALEWLNVYASLAGDSFLNADGTPNFNNENGIKALELLKRASEYMDPEYLVSDSTFVQQQMQQGKIAMANIWASRAGAADNQAESKVVGKIHTAASPLAGEGARPVAMLFWDGVVIPRNISDEAAEAAFRVAMEGLDTEMVQAHNDDAVWLIEGYKPGRLAEGAVATASAQPGPISYPMTIEMGLIHSAIGNQISGFFTGAKSAEAALRAAEEEYGTAAREAGLLQ
>NZ_CP015736.1|WP_168168878.1|974159_974300_-|hypothetical-protein
MPPARVKQIVAAIVLAFSAMPIFLAIDGLTLNMRLTLAVFVATITA
>NZ_CP015736.1|WP_084437764.1|974411_974771_-|hypothetical-protein
MKKVIAILSAFLVVGAAAPAPAVADDPVYRFLQKMTRTSKASQARYGRDRDDDRRGSWSSNRNSNSSSNSNSNRNSNSNSNSNSNSNSNSNSNSNSNNNSNSNSNSNSNSSSNSSSDDD
>NZ_CP015736.1|WP_064329370.1|974948_975665_-|hypothetical-protein
MALALLKKPQPRLTFLCRKEDEGVIPAPVRAKTVLPDWFRKLPAIDETQVSPTNSGITVKRCMPFLDAMAAGWVIGLPASVRMEISDGGKTVDCGWDFDRALVSNHASHQVAGNPREPLPPCKFHNYWTVRTPPGWSCLFVPPLNRPNGVFEVVAGVVDTDTYQSEIHFPFFAIGEDGLHMLERGTPIVQVIPFRRDASDLDADIRAESAPEGAVRKTILRKTLAADGWYRKFARAQR
>NZ_CP015736.1|WP_064329371.1|975750_976044_-|hypothetical-protein
MSDKIEVENINTPGRTERLDRTKYMAMRAALLAALPDTAPGMTVAQAQEALLPHLSETDFPERQKAGWWMKAVQLDLEAKGIIKRAPKRPVQLYRVT
>NZ_CP015736.1|WP_064329372.1|976036_976573_-|hypothetical-protein
MRRTTHIGCACGQTRLEVQGDPILVSECLCNSCRAAAGRLATLPGAKNTLTSYHATPAAEYRKDRVCILSGAENLREFRLSPTAGSRRVVATCCNTPIFLEMKGAHWLSLYLHLWPEAQRPRAELRTMTSDLADRSGLPADIPNLKTHTVAFYGKLLAAWIAMGFRNPKIAVGGTIDV
>NZ_CP015736.1|WP_064329373.1|976574_977207_-|TetR/AcrR-family-transcriptional-regulator
MSRPTKQSPERGNARIRLLEAARDIIREKGFAATTIEDLCKAADVTKGAFFHHFGSKEALGVAAAEFWGETTSAYFAAALYHGPSEPLARVLAYVAFRKAIIAGELQEFTCLVGTMAQEVFVSAPDIRDACGRSMFGHTATLEADIEMARRERGITATGWTAESLARHTQAVLQGGFILAKAANDPALARESLDHLERYIRYLFNVTEDD
>NZ_CP015736.1|WP_064329374.1|977349_978078_-|hypothetical-protein
MNKDDFDDETLMAFADGELDEARSLALEEALATDEALAERLTVFLDSRRLVGEALKPLIDEPVPEALLASVRKMAEEAQSPRDNIVVSFRPKPQQMAQPTTRPWLMPVAASLVALVTGVIGFTLGSMGPSATDSAAEIAAALDREVSGRDIRLSGAVLHVVATFRDERGELCREYELKQEASSTLTVACRQDGAWATRLALTTPQAEGYVPASTQETIDTYLTSIQAGAPLSAEEERKALAP
>NZ_CP015736.1|WP_064329375.1|978074_978617_-|RNA-polymerase-sigma-factor
MTNDMPTVPERLVAFLPNLRRFAISLCRSRELADDLVQAACERAILAADSFAPESRFDAWMFRILRNLWIDHLRRLKTAGPHDDIDEARDVSVPSGEAAAHARMDLAEVTIALQKLPDEQREVLVLVCVEEFSYRDAAEVLAIPIGTVMSRLARARKNLMELTGISFGERRSPDTKGGVS
>NZ_CP015736.1|WP_064332441.1|978979_980113_+|S8-family-serine-peptidase
MRRAVAVPDRAPNEIVATGLDDDAIAGLAQDGFVVDDRVEIALIGGEMVRLIVPQGMTLDAARAAVSARSASATVDFNHFYQPQAGGKAACVREGCALVRHMVGWPSGEAGSGLACLKPQRIGLIDTAINAEHAVLAGTRLEILDLGGGEGAKSGEQHGTAVAALLVGAPGSRVPGLLPGSELVAVDAFQRFRKSTDIASVYDLVRGLDLLIQRNIRVVNLSLTGPANRVLEQAVEAANGRGTILVAAAGNDGPNAEPVYPAAYEVVIAVTAVDTAGNPYRRAVRGAHIDIAAPGVGVWTAASISGARQKNGTSFAAPFVTAAVSLLLSAKPGLSPRDIEAELTKSAEDMGTPGKDNIYGWGLLNARALCRQAKDGK
>NZ_CP015736.1|WP_064329376.1|980416_981223_-|ATP-binding-cassette-domain-containing-protein
MLHPSSLLSDARPLFSLDGISYSVDGRTILHALDLQLFTGKTIGLIGHNGSGKSTLIKILARQITPTAGYIRFGERPLDGWPNREFARNLAYMPQQTPVAAGTRVRELVKFGRYPWHGALGAFRPKDARKVDEALDLTGMTALADRPVETLSGGEHQRAWLAVLVAQDTRCFLLDEPISALDIAHQIAVLDLIRTLTKTKGLSVIMVLHDVNMASRYCDEIIALHGGSLIARGSPQSIMTPDVLKAVYGVDFRVYGETGDGPLSALVR

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Crispr_ID: NZ_CP015736_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015736_2

1121713-1121812

Orphan

Consensus_repeat	Method
GGGACGGTGCCCCATCCAATCTCCCCCCCTTGAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015736_2

>merge|NZ_CP015736|2|1121713-1121812|CRISPRCasFinder
GGGACGGTGCCCCATCCAATCTCCCCCCCTTGAGGCGGCAGCTTCTTCAGAAAGGCAGGACCGATGGGACGGTGCCCCATCCAATCTCCCCCCCTTTGAG

>NZ_CP015736|2|2|1121713-1121812|CRISPRCasFinder
GGGACGGTGCCCCATCCAATCTCCCCCCCTTGAGG	CGGCAGCTTCTTCAGAAAGGCAGGACCGAT
GGGACGGTGCCCCATCCAATCTCCCCCCCTTTGAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015736.1\|WP_064329484.1\|1118862_1119219_+\|monovalent-cation/H(+)-antiporter-subunit-G	unknown	unknown	gnl\|CDD\|237169
NZ_CP015736.1\|WP_145925994.1\|1120750_1121527_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015736.1\|WP_133033150.1\|1129702_1129891_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015736.1\|WP_064329483.1\|1118497_1118863_+\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|237148
NZ_CP015736.1\|WP_064332458.1\|1120461_1120740_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|180356
NZ_CP015736.1\|WP_064332459.1\|1127464_1127836_+\|DUF1491-family-protein	unknown	unknown	gnl\|CDD\|227734
NZ_CP015736.1\|WP_064329491.1\|1125811_1127263_+\|MCP-chemoreceptor-protein	unknown	unknown	gnl\|CDD\|214599
NZ_CP015736.1\|WP_064329490.1\|1124974_1125688_+\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|366659
NZ_CP015736.1\|WP_064329481.1\|1115668_1116088_+\|Na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
NZ_CP015736.1\|WP_064329489.1\|1123476_1125003_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP015736.1\|WP_064329487.1\|1121910_1122330_-\|SufE-family-protein	unknown	unknown	gnl\|CDD\|225077
NZ_CP015736.1\|WP_133033149.1\|1128120_1129035_-\|DUF2336-domain-containing-protein	unknown	unknown	gnl\|CDD\|227638
NZ_CP015736.1\|WP_064329485.1\|1119632_1120067_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|227293
NZ_CP015736.1\|WP_084437800.1\|1116482_1118498_+\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|237163
NZ_CP015736.1\|WP_064329488.1\|1122538_1122964_-\|DUF5330-domain-containing-protein	unknown	unknown	gnl\|CDD\|375087
NZ_CP015736.1\|WP_145925993.1\|1113036_1115358_+\|putative-monovalent-cation/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237156
NZ_CP015736.1\|WP_064329479.1\|1112490_1112907_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|224404
NZ_CP015736.1\|WP_064329482.1\|1116087_1116465_+\|Na+/H+-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|183658
NZ_CP015736.1\|WP_064329494.1\|1130567_1131161_-\|DUF1214-domain-containing-protein	unknown	unknown	gnl\|CDD\|227689
NZ_CP015736.1\|WP_064329493.1\|1130023_1130575_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227723

Protein	Function_ID	Function_description	E-value
NZ_CP015736.1\|WP_064329484.1\|1118862_1119219_+\|monovalent-cation/H(+)-antiporter-subunit-G	gnl\|CDD\|237169	PRK12674, PRK12674, putative monovalent cation/H+ antiporter subunit G; Reviewed.	7.70056e-30
NZ_CP015736.1\|WP_064329483.1\|1118497_1118863_+\|cation:proton-antiporter	gnl\|CDD\|237148	PRK12599, PRK12599, putative monovalent cation/H+ antiporter subunit F; Reviewed.	6.96261e-27
NZ_CP015736.1\|WP_064329489.1\|1123476_1125003_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.54805e-54
NZ_CP015736.1\|WP_064332458.1\|1120461_1120740_+\|hypothetical-protein	gnl\|CDD\|180356	PRK06030, PRK06030, hypothetical protein; Provisional.	7.2657e-31
NZ_CP015736.1\|WP_064332459.1\|1127464_1127836_+\|DUF1491-family-protein	gnl\|CDD\|227734	COG5447, COG5447, Uncharacterized conserved protein [Function unknown].	2.14656e-36
NZ_CP015736.1\|WP_064329491.1\|1125811_1127263_+\|MCP-chemoreceptor-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	1.43068e-26
NZ_CP015736.1\|WP_064329490.1\|1124974_1125688_+\|peptidoglycan-binding-protein	gnl\|CDD\|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	2.84686e-12
NZ_CP015736.1\|WP_064329481.1\|1115668_1116088_+\|Na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	8.76999e-53
NZ_CP015736.1\|WP_064329487.1\|1121910_1122330_-\|SufE-family-protein	gnl\|CDD\|225077	COG2166, sufE, Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones].	2.63649e-65
NZ_CP015736.1\|WP_133033149.1\|1128120_1129035_-\|DUF2336-domain-containing-protein	gnl\|CDD\|227638	COG5330, COG5330, Uncharacterized protein conserved in bacteria [Function unknown].	1.88769e-32
NZ_CP015736.1\|WP_064329485.1\|1119632_1120067_+\|transcriptional-regulator	gnl\|CDD\|227293	COG4957, COG4957, Predicted transcriptional regulator [Transcription].	1.37026e-82
NZ_CP015736.1\|WP_084437800.1\|1116482_1118498_+\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|237163	PRK12663, PRK12663, Na+/H+ antiporter subunit D.	0
NZ_CP015736.1\|WP_064329488.1\|1122538_1122964_-\|DUF5330-domain-containing-protein	gnl\|CDD\|375087	pfam17264, DUF5330, Family of unknown function (DUF5330). This is a family of unknown function which is mostly found in Bacteria.	1.10753e-26
NZ_CP015736.1\|WP_145925993.1\|1113036_1115358_+\|putative-monovalent-cation/H+-antiporter-subunit-A	gnl\|CDD\|237156	PRK12647, PRK12647, putative monovalent cation/H+ antiporter subunit A; Reviewed.	0
NZ_CP015736.1\|WP_064329479.1\|1112490_1112907_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|224404	COG1487, VapC, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	5.21641e-12
NZ_CP015736.1\|WP_064329482.1\|1116087_1116465_+\|Na+/H+-antiporter-subunit-C	gnl\|CDD\|183658	PRK12658, PRK12658, Na+/H+ antiporter subunit C.	1.74879e-61
NZ_CP015736.1\|WP_064329494.1\|1130567_1131161_-\|DUF1214-domain-containing-protein	gnl\|CDD\|227689	COG5402, COG5402, Uncharacterized conserved protein [Function unknown].	3.65134e-75
NZ_CP015736.1\|WP_064329493.1\|1130023_1130575_-\|hypothetical-protein	gnl\|CDD\|227723	COG5436, COG5436, Predicted integral membrane protein [Function unknown].	1.73872e-66

>NZ_CP015736.1|WP_145925994.1|1120750_1121527_+|hypothetical-protein
MDDAALAKVLRFLLAVGEARLAEDAVLAADGRRQPLAPAVLAEALRLGLVGRKGERLFAAAEARAYLKRRLCTAETPFALQHRDMAEVTVLRDGVRERALANRLESPLASLTRLKEKTGEAFLPDTALAAGERLHADFTRGGLQPRLTMSWEPRIAGRQKGEAGAARELTDTALAARLRVARAIAAIGPELSGVALDVCCFMKGLETVERERQWPARSAKLMLRAALMALARHYAPPAPAGRRAHAWGAEGYRPDLPG
>NZ_CP015736.1|WP_064332458.1|1120461_1120740_+|hypothetical-protein
MTAMAGDRSLFRRDSRRSTCHVRQIAMYVCHVVLQLSLSDIGAAYGRDRTTVGHACNVVEDRRDDAAFDAFVSAIERVVLSVFGPAGIGSHA
>NZ_CP015736.1|WP_064329485.1|1119632_1120067_+|transcriptional-regulator
MTETTLGAGSNLLVELTADIVAAYVGNHVVPVSELPGLIADVHAALNNTTQPAAAVEVPVVAEKPKPPVPVKKSVQNDYIICLEDGQKFKSLKRHLMTHYGMTPEEYREKWDLPADYPMVAPAYAEARSRLAKEMGLGQRRKGK
>NZ_CP015736.1|WP_064329484.1|1118862_1119219_+|monovalent-cation/H(+)-antiporter-subunit-G
MLDLVLAVIVAVMLVAGGVFTFLAALGIVRLPDVYTRMHAASKAGTVGSGLMLFAAGIHSLDAAIFTRALAGFVFFVLTAPIAAHLIARAAHEAGYRLSRHTVLDEMRDARERSNKKR
>NZ_CP015736.1|WP_064329483.1|1118497_1118863_+|cation:proton-antiporter
MGAETVISAAATFALFLMCAAFFLTAYRVIKGPTLPDRIVALDMLVAIAIGFIAVLAIRTGFNLYIDIAIALGLVGFLATVAFARFVLRQGMEADEPAAEGESPGRRGGRQRKAAKARRRR
>NZ_CP015736.1|WP_084437800.1|1116482_1118498_+|Na+/H+-antiporter-subunit-D
MAATPTDLSEALVMTPVATADWLVVLPPAWCILAGAVLLMARKSLHLQGFLAIPALAVLVLLDALLLAHVAANGPVTMVMGRWLPPFGIAFTADLTGVLFALAGAVVALAGAVHALTDIDGSGRRYGFYPFLLLLMAGVSGAFLTGDIFNLYVWFEVLLISSFGLITLGSEPRQIDGAIKYAFLNLIATTLFLITTGYLYGIFGTLNMADIAAKAAASRAELPLMTLAMLYLTAFGMKAAAFPVNFWLPASYHTPRIVVSALFAGLLTKVGIYALLRTLIMLFPVEREELSFVIALTGAATMLLGALGALGQNDIRRLLGYLVISGIGVMLAGLSLGSPGGTGGAIFYALHSMVVMTGLYMAAGLAGRLSGTFDLSRLGGLYARSALFSALSLVLFFAVSGLPPFSGFWPKVMVAKAAMDIGAWWLAAVVFLSGFLTTIAVGRVFLLAYWRPAGGALSAETIPASALLPLAVLTALTAVFGLFPEALLSTIQLAAQGLADPRAYIGSVFPGGTDMRPAFTVALFALAWLAVSGSFTIANLLLGLVAGGLSLALIRDHIRPDGRRVRPLKLLSLVLLFIKELALSAWKVAVLVASPKMVLKPGIFAFPLTVDRDFEITLLANLITLTPGTLSVDVSADRKVLYVHALDCSDPVGARRDIAGGFEKKILEAFR
>NZ_CP015736.1|WP_064329482.1|1116087_1116465_+|Na+/H+-antiporter-subunit-C
MEVPFVLLIGLFFSAAVYLMLSKFLVRVLLGVVLLGNAVNLLIFTNGRILREVPPIIPVGHDVPQALTANPLPQALILTAIVISFSFFAFLLVLVYRAYQDLGTDNGNEMRLAEPENDPLPPTGY
>NZ_CP015736.1|WP_064329481.1|1115668_1116088_+|Na(+)/H(+)-antiporter-subunit-B
MNTLIFRTVAPFLTALMVLFSLFVLLRGHNEPGGGFIGGLIAVSAFAIYGIANGIAAVRKALWFHPMTISAFGLFIAAIAGLMSIFFAVPFMTGLWVYPVILGVEIPLSSVMLFDTGVYLVVVGAITSIALALEAEEDA
>NZ_CP015736.1|WP_145925993.1|1113036_1115358_+|putative-monovalent-cation/H+-antiporter-subunit-A
MGLTFLAFCLPFLGALVAPALTRLLGHHAAWPLALVPAAIFLHFLGFNAEVSRGEIVTGGYAWVPSYNVSFSWLIDGLSLAFLLLISGIGALIVLYAGGYLKGHPHQGRFFSFILMFMGAMLGLVASDSFLMLFVFWELTSITSFLLIGFDHAREAARRAALQALVVTGGGGLFLLAGLLLLWNVTDVTQLSLLMSFGAEVRASPFYLPLLFLILGGAFTKSAQFPFHFWLPNAMEAPTPVSAYLHSATMVKAGVYLLMRLNPVMGDTPAWETILPAFGGLTLLVGAVLAIRQTDLKLMLAYTTVASLGLLVMLTGFGSQHAVAAAALYLVAHSLFKGALFMVAGLIDHETGTRDITRLGGLKRAMPVTFLAALLAALSMAGLPPFFGFLAKEEIYAALAGGSLRAIAFTAAAVIGNGLMFAVAFAVALKPFLGAPVETPKHAHEGPALLWIGPMLLAIKGLVIGLFSAVAHALLTSPLASAIAGKPETVTISAVPHLGLALALSVVTIVFGAAVFLLIDKARAAANRLVEDIGWGPDRGFDQVMTGLVRAAAAITRRVQPGRMEIYMTATFAVIALALLVPPAVYGEWPRLPVWPADMPFHELAVMALAVLGIGAVLTASNRLTAIVALGIQGFCVAMLFLLFGAPDLAFTQFMIETLSVVILALVMTRLKLTPRDHRPLREKVPDAVIAIACGLGFSLYLLKVTQGRFDTALTDFFNLYSKTIAHGANVVNVIIVDFRGTDTLGEIAVVMVTGLAILSIIRIRKGKAGGKV
>NZ_CP015736.1|WP_064329479.1|1112490_1112907_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MFLVDTNVLLDLVTEDPAWAAWSQAELEAAALLGPLGINDVVYAELSVRYRDIADLDAMIALAQLDHLPMPRQALFLAGKAFQAYRRTGGSRTGVLPDFFIGAHAAVAGLTLITRDAARYRTYFPNLAVRTPDAREGG
>NZ_CP015736.1|WP_064329487.1|1121910_1122330_-|SufE-family-protein
MATLQEIIDDFAFLDEWEDRYRYVIELGKALPDLPEEQRTAANKVQGCASQVWLVSQVGAGADPVMTFTGDSDAHIVRGLVAIVLAIYSGKRASEIAALDAIDTFNAIGLVEHLSSQRANGLRSMVRRIREEAAMRVAA
>NZ_CP015736.1|WP_064329488.1|1122538_1122964_-|DUF5330-domain-containing-protein
MWFLIKGTFWFSLVLVLLPFLDAESSAKLEKGPTVEIGGTFTAASEALHYVTAMCLEKPDVCEKGAETFVALGHRAREGARIAYQFLDTQFAEEGTAVAKADPAAREALDQPLPAMATIDADDEVITGTVAIPTRRPDHKG
>NZ_CP015736.1|WP_064329489.1|1123476_1125003_+|HAMP-domain-containing-histidine-kinase
MAARLGAVAGVAGASVADQRPSASLRATTLALLAAVPGLPLILSAVMPASAALPAGVALAGAGALLTAAAATLKEKPAPRKSFAEELAAAAPPAASPYDLFAGLVTLHDARGFVTAVHGRDRADMLAWMRDPMGRGYLDQIHVSDRIGFLAAIDRLRQGGTRETVELRIDRPRIEADAEQFTHMRVEMTALAGADGALSAVVAQSRDMSDEARLRGESARKAAEAESANDAKTRFLAAVSHELRTPLNAILGFSDILAGEYFGKLENDRQREYVTLIHQSGSHLLSVVNTMLDVSKIEAGRYELMSEPFLVADSVKACEQMLGLQAREKGIKLTSRVPRAIGEAVADQRAIQQVLINLVGNAIKFTDRGGIVTIDATREGRDLILTVSDTGIGIPADKLALIGQPFMQVQNEYTRKYEGTGLGLSLVKGLVALHGGSFLIQSRPGEGTVISVRVPADGSGIAQENDLRPGPASTVEFPPRLAAVIETVYEPSRDGKDTNDERARQKTA
>NZ_CP015736.1|WP_064329490.1|1124974_1125688_+|peptidoglycan-binding-protein
MNAHVRRQPERRPQGQTRKGRSGTRVEPRRPNIVIAALAALGGLAARHPTVVGGTCAFVVVFSFVAANALWYQPGGHPAPFLKMRSADNSLGFTATKPEPHDVTTFVIERAEEGEPLPEVTDVTPAERPFDEVAKVIESKPAQTQADVEEDPVAAAILQAEADPAVTSAVARPVPSELVMKIQKGLSNIAYTDIAVDGLIGEKTRTAIRHFEKHYRLPVTGEPNEKVLAKLKDIGAL
>NZ_CP015736.1|WP_064329491.1|1125811_1127263_+|MCP-chemoreceptor-protein
MSNAALRETAHTRNEDEGQAPVDGAALRRVVGSLAVEASDLGLHLVDIAGSIQDTAAQSREHATLFTRLTQSATAIASANGDIARSLGETDQLAASARQVLGEQAVQLDGSIAAIDHMVTASNEIGTEISAFSGALADVGRLADAIGTIARQTNLLALNAAIEAARAGEAGKGFAVVAAEVRALSLETSSTTASIQKTLQALRARIDRLEAAGEEARVSAEGVKATASQVQGSFAGVEEVMSKILDSASALAATTGAVDRECSDFARSIGAASAEIIRSNETLQGASGKVGEVVAISERIIQATASAGIETPDSPYIRLVQQLADKVSARFSAAVASGEMGMEALFDRQYRPIPGTDPVQMTTRFTDFTDRVLPDIQEPAVAADTRIAFCAAIDDRGYLPTHNRKFSEPQRPGDPAWNTANCRNRRIFDDRVGLAAGRSTEPFLVQTYRRDMGGGQFVLMKDISAPITVNGRHWGGLRLAIRV
>NZ_CP015736.1|WP_064332459.1|1127464_1127836_+|DUF1491-family-protein
MRLRSDIFVSALMRRVFARGDFAAVEVKGAEEAGAVFVRQVFRDGAESLHAPAPQSFFEAEESGLRRFETRLERVEAPAVAEALARERRFDGDLWVVSIETDDLGDLIDFAAAEPKDDGFFRR
>NZ_CP015736.1|WP_133033149.1|1128120_1129035_-|DUF2336-domain-containing-protein
MATVSSFESLRFPSRSDLRQFGELFEPLYNASTEEARRQAVAALSRCPQVPDETALFIATQPIGVAAIFLMGSKAIADRTLMHVLRAAGPEHARAIGRRDDLSPAVVEALVASHQDHASRRVGEDREASLKEAARLEREEQIREELRALVRAATPAVEAPLGLEPATEAHQALFVRFARAGEAGMLAVTLADALGSSQWLSERILLDVSGRQLAETLLALDVPDADSLFVLTKIYPHLAEGGAAALLSALDPAEAIDRVESWQRADSYTNGNGLPKAANADDAQSNGQDHHDRSSEATRHRAAG
>NZ_CP015736.1|WP_133033150.1|1129702_1129891_+|hypothetical-protein
MADVVRLKEWLARTPRRDTIRREAPAQVLLFTGVRYERLTPAMLAARGKAAKQGAPDTARRP
>NZ_CP015736.1|WP_064329493.1|1130023_1130575_-|hypothetical-protein
MRSLLYAIAVGLVGAALLHIVIILSLPSFTGRDAYTRVQAFGETNRFFPLAGNSDSLAPINDDPSMKTAVCAFSVESGPIRLFAEGEVPFWSLAVYDSASNEVFSMNDRTSVSSALDTLIATPIQLIAIRKAVPAELERSILVEMRGEEGYAVLRTFVPTQSREEAAIAFLAEASCEPFTAEQ
>NZ_CP015736.1|WP_064329494.1|1130567_1131161_-|DUF1214-domain-containing-protein
MFRTPLVIATALAVAFGLGILSSIYALRATVGFGAIALGPWTAFPTAQTVDADPYAKAHRARDGKLLLGSAEGLTFTAATDSANRTLVENCRYEIRGITPPARLWTLHAADRNGNPLEDARPGLPTGLNAWSVLRGADSTFSIRIASSATPGNWLAVPEGRAPFLLVMTLLDTPTAGSSGVIDLAMPGITRLDCADA

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Crispr_ID: NZ_CP015736_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015736_3

2032348-2032967

Orphan

Consensus_repeat	Method
GCCGCCGAGCGCATCGACGGCACGCT	CRISPRCasFinder
GCCGCCGAACGCATCGACGGC	PILER-CR

9 spacers

The CRISPR arrays of NZ_CP015736_3

>merge|NZ_CP015736|3|2032348-2032967|CRISPRCasFinder,PILER-CR
GCGGCCGAGCGCATCGAAGGCGCCCTTTCCGGTCGCCTCACCGATATCGAGCGTGTCACCGGCGAAGCCGCCGAGCGCATCGACGGTACGCTGGCAAGCCGTGCCGACCAGATCGCCCGCATTGCCGGGGAAGCGGCGGACCGCATCGACGACACGCTGATTGCCCGCGCCACCCAGATCGAGATGACCGTCGGCAACGTCGCCGAGCGTATCGACGACACGCTGCTGGCCCGCGCAACGCAGATCGAACTGACGGTCGACAATGCCGCCGAGCGCATCGACGGCGCCCTTGTCGGCCGCGTCGACGAGATCAGCCGCACCGTCGGCGAGGCCGCCGAACGCCTCGACGGCACGCTCCTCAACCGGGCAAGCCAGATCGAGCGGTCCGTCGGCAATGCCGCCGAACGCATCGATGGTGCCCTCGTCAATCGCGCCGACGAGATCAGCCGCGCCGTCGGCGAGGCCGCCGAGCGCATCGACGGCACGCTGGCAAGCCGCGCCAGCGACATCGCCCGCATTGCCGGGGAAGCCGCCGAACGCATCGACGGCACGCTCACGGCCCGCACCGGCGACATCGAACGCATCACGGGCGAAGCCGCCGAGCGCATCGCCGGCACGAT

>NZ_CP015736|3|3|2032348-2032967|CRISPRCasFinder
GCGGCCGAGCGCATCGAAGGCGCCCT	TTCCGGTCGCCTCACCGATATCGAGCGTGTCACCGGCGAA
GCCGCCGAGCGCATCGACGGTACGCT	GGCAAGCCGTGCCGACCAGATCGCCCGCATTGCCGGGGAA
GCGGCGGACCGCATCGACGACACGCT	GATTGCCCGCGCCACCCAGATCGAGATGACCGTCGGCAAC
GTCGCCGAGCGTATCGACGACACGCT	GCTGGCCCGCGCAACGCAGATCGAACTGACGGTCGACAAT
GCCGCCGAGCGCATCGACGGCGCCCT	TGTCGGCCGCGTCGACGAGATCAGCCGCACCGTCGGCGAG
GCCGCCGAACGCCTCGACGGCACGCT	CCTCAACCGGGCAAGCCAGATCGAGCGGTCCGTCGGCAAT
GCCGCCGAACGCATCGATGGTGCCCT	CGTCAATCGCGCCGACGAGATCAGCCGCGCCGTCGGCGAG
GCCGCCGAGCGCATCGACGGCACGCT	GGCAAGCCGCGCCAGCGACATCGCCCGCATTGCCGGGGAA
GCCGCCGAACGCATCGACGGCACGCT	CACGGCCCGCACCGGCGACATCGAACGCATCACGGGCGAA
GCCGCCGAGCGCATCGCCGGCACGAT

>NZ_CP015736|3|2|2032612-2032962|PILER-CR
GCCGCCGAGCGCATCGACGGC	GCCCTTGTCGGCCGCGTCGACGAGATCAGCCGCACCGTCGGCGAG
GCCGCCGAACGCCTCGACGGC	ACGCTCCTCAACCGGGCAAGCCAGATCGAGCGGTCCGTCGGCAAT
GCCGCCGAACGCATCGATGGT	GCCCTCGTCAATCGCGCCGACGAGATCAGCCGCGCCGTCGGCGAGGCCG
CCGAGCGCATCGACGGCACGC	TGGCAAGCCGCGCCAGCGACATCGCCCGCATTGCCGGGGAAGCCG
CCGAACGCATCGACGGCACGC	TCACGGCCCGCACCGGCGACATCGAACGCATCACGGGCGAAGCCG
CCGAGCGCATCGCCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015736.1\|WP_064330238.1\|2027571_2027892_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|223706
NZ_CP015736.1\|WP_064330247.1\|2043494_2044331_-\|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl\|CDD\|225460
NZ_CP015736.1\|WP_064332520.1\|2044565_2046878_+\|NADP-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|183799
NZ_CP015736.1\|WP_064330231.1\|2021235_2022711_+\|GTP-binding-protein-YcjX	unknown	unknown	gnl\|CDD\|225648
NZ_CP015736.1\|WP_064330242.1\|2037607_2038978_-\|MCE-family-protein	unknown	unknown	gnl\|CDD\|224380
NZ_CP015736.1\|WP_064330235.1\|2025018_2025387_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|224456
NZ_CP015736.1\|WP_084437892.1\|2039832_2041017_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223838
NZ_CP015736.1\|WP_064330237.1\|2026523_2027135_+\|DUF922-domain-containing-protein	unknown	unknown	gnl\|CDD\|227948
NZ_CP015736.1\|WP_064330233.1\|2023969_2024518_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015736.1\|WP_064330234.1\|2024510_2025029_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|223872
NZ_CP015736.1\|WP_064330239.1\|2028095_2028464_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225108
NZ_CP015736.1\|WP_064330236.1\|2025410_2026283_-\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|238380
NZ_CP015736.1\|WP_064330230.1\|2020552_2021077_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|224973
NZ_CP015736.1\|WP_168168950.1\|2036855_2037458_-\|ABC-transporter	unknown	unknown	gnl\|CDD\|225759
NZ_CP015736.1\|WP_064330245.1\|2041114_2042098_+\|dipeptide-epimerase	unknown	unknown	gnl\|CDD\|239435
NZ_CP015736.1\|WP_064330248.1\|2046995_2047358_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP015736.1\|WP_064330243.1\|2039038_2039824_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224052
NZ_CP015736.1\|WP_064330232.1\|2022707_2023769_+\|TIGR01620-family-protein	unknown	unknown	gnl\|CDD\|226291
NZ_CP015736.1\|WP_168168902.1\|2035654_2036626_+\|Tim44-domain-containing-protein	unknown	unknown	gnl\|CDD\|226830
NZ_CP015736.1\|WP_064330246.1\|2042067_2043285_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|236856

Protein	Function_ID	Function_description	E-value
NZ_CP015736.1\|WP_064330238.1\|2027571_2027892_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|223706	COG0633, Fdx, Ferredoxin [Energy production and conversion].	3.60157e-27
NZ_CP015736.1\|WP_064330247.1\|2043494_2044331_-\|UDP-2,3-diacylglucosamine-diphosphatase	gnl\|CDD\|225460	COG2908, COG2908, Uncharacterized protein conserved in bacteria [Function unknown].	4.4988e-100
NZ_CP015736.1\|WP_064332520.1\|2044565_2046878_+\|NADP-dependent-malic-enzyme	gnl\|CDD\|183799	PRK12862, PRK12862, malic enzyme; Reviewed.	0
NZ_CP015736.1\|WP_064330231.1\|2021235_2022711_+\|GTP-binding-protein-YcjX	gnl\|CDD\|225648	COG3106, COG3106, Predicted ATPase [General function prediction only].	0
NZ_CP015736.1\|WP_064330242.1\|2037607_2038978_-\|MCE-family-protein	gnl\|CDD\|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	3.02548e-48
NZ_CP015736.1\|WP_064330235.1\|2025018_2025387_-\|dihydroneopterin-aldolase	gnl\|CDD\|224456	COG1539, FolB, Dihydroneopterin aldolase [Coenzyme metabolism].	7.43172e-41
NZ_CP015736.1\|WP_084437892.1\|2039832_2041017_-\|ABC-transporter-permease	gnl\|CDD\|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	7.22297e-96
NZ_CP015736.1\|WP_064330237.1\|2026523_2027135_+\|DUF922-domain-containing-protein	gnl\|CDD\|227948	COG5661, COG5661, Predicted secreted Zn-dependent protease [Posttranslational modification, protein turnover, chaperones].	5.79348e-80
NZ_CP015736.1\|WP_064330248.1\|2046995_2047358_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.47145e-33
NZ_CP015736.1\|WP_064330234.1\|2024510_2025029_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|223872	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism].	1.95955e-67
NZ_CP015736.1\|WP_064330239.1\|2028095_2028464_-\|transcriptional-regulator	gnl\|CDD\|225108	COG2198, ArcB, FOG: HPt domain [Signal transduction mechanisms].	0.00284312
NZ_CP015736.1\|WP_064330236.1\|2025410_2026283_-\|dihydropteroate-synthase	gnl\|CDD\|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	3.66672e-114
NZ_CP015736.1\|WP_064330230.1\|2020552_2021077_+\|histidine-phosphatase-family-protein	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	8.71769e-44
NZ_CP015736.1\|WP_168168950.1\|2036855_2037458_-\|ABC-transporter	gnl\|CDD\|225759	COG3218, COG3218, ABC-type uncharacterized transport system, auxiliary component [General function prediction only].	4.90152e-73
NZ_CP015736.1\|WP_064330245.1\|2041114_2042098_+\|dipeptide-epimerase	gnl\|CDD\|239435	cd03319, L-Ala-DL-Glu_epimerase, L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of the murein peptide of peptidoglycan, of which L-Ala-D-Glu is a component. L-Ala-D/L-Glu epimerase is a member of the enolase-superfamily, which is characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	3.8626e-126
NZ_CP015736.1\|WP_064330243.1\|2039038_2039824_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224052	COG1127, Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism].	8.80901e-138
NZ_CP015736.1\|WP_064330232.1\|2022707_2023769_+\|TIGR01620-family-protein	gnl\|CDD\|226291	COG3768, COG3768, Predicted membrane protein [Function unknown].	4.67857e-141
NZ_CP015736.1\|WP_168168902.1\|2035654_2036626_+\|Tim44-domain-containing-protein	gnl\|CDD\|226830	COG4395, COG4395, Uncharacterized protein conserved in bacteria [Function unknown].	4.5217e-64
NZ_CP015736.1\|WP_064330246.1\|2042067_2043285_-\|MFS-transporter	gnl\|CDD\|236856	PRK11128, PRK11128, 3-phenylpropionate MFS transporter.	4.03812e-54

>NZ_CP015736.1|WP_064330239.1|2028095_2028464_-|transcriptional-regulator
MAALNIAFEAPDNAGGMSHSGEKPIDLVHLARQTMGDKGLELDVLQMFARQARASMKELAICEGAARAAVAHRLKGSAQSVGATAVSRTAAALEDNPADAIALAGVAAAVVEAENFILKLCR
>NZ_CP015736.1|WP_064330238.1|2027571_2027892_-|(2Fe-2S)-binding-protein
MSKLTIVAFDGTRHELDVANGSTVMENAVRNSVPGIEAECGGACACATCHVYVDDAWSAIVGPPEAMEEDMLDFAYEVRPTSRLSCQIKMSDALDGLVVHVPERQA
>NZ_CP015736.1|WP_064330237.1|2026523_2027135_+|DUF922-domain-containing-protein
MTTIARLMALAALACLALQPARAETITSKTFAYFSVGGRTAAELDEELSKRGPVMKHSGARHPGATRIKWGGSVTYVRRGSRCAVGEARVTLSTEIILPRWKHRKRATPSLALIWDTLSSDIKRHEERHAEIARTHARNLERTLKTLRPEADCERMQARVDRATADAVSKHDADQARFDRIESKNFNDRMMRLLVHRLKSRAE
>NZ_CP015736.1|WP_064330236.1|2025410_2026283_-|dihydropteroate-synthase
MFSPFEPFRWALAHGRSLELGPRGILMAIVNVTPDSFSDGGRFDSADKAVAQAVLCLEEGAEIVDIGGESTRPGAAPVSAAEEQDRILPVIEALAGTTDALISVDTYRAETARLAVAAGAHIVNDVHGLQREPDIAGVAAGTGAGLCIMHTGRDRQKRPDVVEDQYLFLGRSLEIARAAGIAREAMVLDPGFGFAKDTDENLELMARFGELYGFELPILAGTSRKRFVGAVTGREAEGRDAGTAATTALLRVAGAAVFRVHDVAINRDALAMADAMLAAGRKVTAREART
>NZ_CP015736.1|WP_064330235.1|2025018_2025387_-|dihydroneopterin-aldolase
MTTTYTITLKNCAFFARHGLHDAEEFLGQRFFVDAELEVRPLRPLSDDAIESTVDYGVAFQEIEKIVTGQRRYLIEALAQEIATVLCARFPQISRARITVRKPNAPVPGVLDHVQVTVDHAV
>NZ_CP015736.1|WP_064330234.1|2024510_2025029_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MPFEPFRQAALGLGGNIGDPVRAMAEALRALDARDDCRVTAVSRLYRTPPWGKTDQDWFFNACALVETTLAPEPLLDTCLAIERDMKRERKDRWGPRTIDIDVLTYDGVAQSGGRLDLPHPRMTGRGFVLMPLADVAPDLAVEGRTVASWLEDADVAGIEPASAGPEWWKAT
>NZ_CP015736.1|WP_064330233.1|2023969_2024518_+|hypothetical-protein
MYSRTSLIARVSVAAFLAATAVALPASAGSRDKAFFEQVTGSWQGKGEIVAGKYKGTKFACDLTGDTAPAKGAGIQLDGFCRVGVFKQPMSALITRSGSTYKGKFLDGAAGKGLDITSGQVNGNKVVVGINRQKLNGAMIARLDGDNKMNITISVKVEDKMVPVIGVSLDRNLDDIAVGSIK
>NZ_CP015736.1|WP_064330232.1|2022707_2023769_+|TIGR01620-family-protein
MNDRPRKPAAFSLPGGSPQPPERTRPRAPAAFDDAVTLTPDAEDPFIATTADLPDLTPPVATPRKRRLTLGRIALGALGLLVSLAIGLWVDALIRDLFSRNDWLGYLAIAAAAIAVLAVLGLVARELIGLRRLAAVQDLKRDVAEAALSPSPSVGRAILARLVHLAAARPQTARGRARLAETEGEIIDAAHLVDLAERELMAPLDREARALILGAAKRVSIVTAVSPRALVDLGYVVYESSRLVRGMAELYGGRPGKIGMLRLMRDVIAHLAVTGSIAMGDSLVQQVLGHGLASKLSARLGEGVINGLMTARIGIAAMDLCRPMPFRALKRPGIGDFIGDLTPNMAGGRREEA
>NZ_CP015736.1|WP_064330231.1|2021235_2022711_+|GTP-binding-protein-YcjX
MPPSLTTLTDEALLALDALTGRATNLVNPSIRLGVTGLSRAGKTVFISSLVHNLLNGGRLPLFEAGRSGRVSKIRLEPQPDDAVPRFQYEDHIRALVADRLWPDSTRAISQLRLTLDYESASGWGRLFSPGRLSIDIVDYPGEWLLDLPLLAQDFRAFSANTVSLAQSGIRAELARDWLALSATMDPAAEAEEATARTLAEAFTAYLKACKSDERSLSTLPPGRFLMPGDLEGSPALTFAPLPNLQEGRPARGSLHAMMERRYEAYKTHVVRPFFREHFARLDRQIVLIDALQAINRGAEAVHDLERALGDVLDCFRAGTNSFLSSFVTRRIDRIVIAATKADHLHHESHARLEAVTRRLVERAIERIGMSGAGIEVMALASVRATREATVKHDGEELPVIVGVPMAGERINGEVFDGERKTAIFPGDLPKDPDSLFKELESLPQGEAPHLLNFVRFRPPHIEETGGGLKLSVPHIRLDRALQYLIGDRLA
>NZ_CP015736.1|WP_064330230.1|2020552_2021077_+|histidine-phosphatase-family-protein
MASLGTPAFRLYILRHARAAWAEPGQSDFDRALDDDGFAEAEVIAEEAADQGYRPDLIISSTATRCRQTAEPFHRSVSEDLTIDYVDSLYSGSVDTYAELAFAERQESAVMIVGHNPMIEEFFHRLVGKEIAETAAPFGYPTAGLAILDFDERPTEDDYRGACLAGFMTPRPAH
>NZ_CP015736.1|WP_168168902.1|2035654_2036626_+|Tim44-domain-containing-protein
MIFIQGFGRILATLAVAVMVMMTVVDVAEARRAGGGFGSRGSRTFSTPSTTRTAPTDAQPIDRTMTRQQSAQPSAGRNATATNPRPGLFGGFGGTLLGGLMLGGLVGMLLGQGLGGGIGFLGLILQVLLIAGLFLFLRRMFAQKNAPAYAGAAHARNAAPNNGPDFKIPSIGGGSRQATPQPKGGDEIGIKQADLEQFESMLKELQAAYAAEDFRTLRQITTPEAMSYLAEELGDNATQGLKNEVRDIHLVQGDIAEAWREGADEYATVAMRYESIDVMRDRATGALVSGDPDNLTEAVEIWTFVRRNGSDWKVSAIQGVENA
>NZ_CP015736.1|WP_168168950.1|2036855_2037458_-|ABC-transporter
MGLLRNGTAARAALVAVLATMLAACGSTQARNDTFALTSVATADGPSVRSRQILVPQPSALKALDGEQIVIRPSASEIQYLAGAQWSDSLSKMVQAKLVQAFENTGRLGGVGMPGQGLAIDYQIVTDIRAFEVQTAGADAAVVEISAKLLNDRNGTVRAQKVFRATVPVGGTGNPAFVRALDAAFAAVTADIVGWTLGTI
>NZ_CP015736.1|WP_064330242.1|2037607_2038978_-|MCE-family-protein
METKANYALVGFFTVLVMAAAFVFVYWMSQYGRGGEMAQLAIRIPGSANGLSIGSPVRFNGIPVGSVRSLAIDADDPRFSVAMTEVSTSAPVKQSTTAVLEVQGLTGAAYIELSGGSAGDPNILRQAVDNEVPAVLQAEQSSVTNILSTADKILKRADAAITDIQGFVADARGPLTTTIQNAEQFSGALARNGEKVDQFLQSVGGLSETFRNLSGQLDSTLASVDALIKAVDPKKVEDFVGNVDKVSRDIADASGDIKATVEGFRKTAETFDTFGKQATVTLDKVDSLVAAVDTQKVGGAIDDISVATADARKAIASVTGVANRIGAREEDIDQIITDVQQMSNKLNAASTRVDGVLAKLDGFLGEGDSESLFAEAKATLQSIKQAADTLNGRIGPIADGLQRFSGSGLRDVEALVLDTRRTIQNLDSAISGFERNPQRLLFGGETVKQYDGRNRR
>NZ_CP015736.1|WP_064330243.1|2039038_2039824_-|ATP-binding-cassette-domain-containing-protein
MEQVSAKADDVMLSVKDLTVGFGSNIVLDKLNLDIYRGEILGFVGASGTGKSVLMRTVLRLLRRRSGTIRIFGLDFDKASEAERLALDMKLGVLFQHGALFSSLTVKENIQVPMREYLDLPQAMMDELARLKIELVGLAPEAANKYPSELSGGMIKRAALARALALDPALVFLDEPTSGLDPIGAAEFDELIAKLRDTLGLTVYMVTHDLDSLFSVCDRIAVLGQKKVMVEGTIEDMLAFDDPWVQSYFRGKRARSIVRKT
>NZ_CP015736.1|WP_084437892.1|2039832_2041017_-|ABC-transporter-permease
MLSQAREDARDLTGARSPLDIAIEKLPGKDGEVWRLSGEWVNTTAVAASKRLADIGRGQGGALEIDLGGVTAMDTAGAWLLRRAITERQGGGGAVSLTDREGTHYADLISALPEKLAEPRDEGGGKGTLFERIFEPVGRTVVDIWEDAVAAMFILGSAVRGAQLKLGRRSGVSPSAIVHQIDHMGVRAVPIILLMSFLIGAIIAQQGAFQLRYFGAEVFVVDLVGILQLREVGVLLTAIMIAGRSGSAITAEIGSMKMREEIDALKVMGLSPIGVLVFPRLVALTVALPLLTIIANFAALGGAAFVAWSYSGITFDTFLSRLREAIDLSTVVSGMIKAPFMALIIGIVASVEGLKVGGSAESLGRHVTAAVVKSIFVVILVDGLFAMFYAAIDF
>NZ_CP015736.1|WP_064330245.1|2041114_2042098_+|dipeptide-epimerase
MRRTMLATAESFPIAGTFTISRGAKTTAEVVTCTIKGSGLSGRGECVPYARYGESVAGVLAAIEDMRGAVEDGMGREELARIMPAGAARNAIDCALWDLEAKLSGVPTWQVINAAPPQELVTAYTLSLGEPEAMQRQAAQEAGRPLLKVKVGTADDAARIRAVRAGAPESAIILDANEGWTPENLAHHLALCAEARIALVEQPLPAGNDSALRDLARPVPICADESVHRTQDVKSLIDRYDAINIKLDKAGGLTEALALREAAKEHGLKIMVGCMVGTSLGMAPAVLLAQGADFVDLDGPLLLARDREPGLRYEGSTVYPPDAALWG
>NZ_CP015736.1|WP_064330246.1|2042067_2043285_-|MFS-transporter
MNAPSGFTVTAGAPPFFAARIALVFCAPMMVNGIALPFFPVWLETLSMSDFQIGIVLAVPMFVRVFTAPVAGIIADRIGERSIVLLWSALLSLLTALALFATGSFWPVLLLYTLQGAVYSPYVPITEAIMLSGVRRWNFDYGKMRLWGSLAFIVATMIGGWLAGLYGGAMVLPAMAVAFVLTVLGAVIAPRIGKPRRPSPIAAIATMPTKSTLRQADVQLMLIGVSLVNASHAMLFAFSAIYWQKMGFSGVDVGILWSAGVLAEVVFFLFAVQLRRRFDLWSMMMVGGAVAVGRWVLFPMDMSFAGYFALQCLHAFTYALIHMSAQSRLVERVAEEQEAAAQGLYFFYTGVFTALATFVSGYAYSWYGVQGFYLMSLVAAAGLLSVIAGRVVAPRAQPQSAASGG
>NZ_CP015736.1|WP_064330247.1|2043494_2044331_-|UDP-2,3-diacylglucosamine-diphosphatase
MTATLADPNVRHFRTLFISDVHLGSKAAKADFLIDFLRHHEAETIVLVGDIVDGWRLKRNWYWPQAFNDVTQKLLRKARKGTRIIYIPGNHDEFLRDFPGTHFGGVEVADRIIHEAADGKRYLVLHGDEFDVVVRHARVVAYLGDWAYDAAIAINVVFAAIRRRLGLPYWSFSSWAKQQVKTAVNFIGEFQKVVVDEARRHDADGVICGHIHHAVITEIDGIRYINSGDWVESCTAIAEHHDGEMELITWQKLAANPAEVVPVSRRMLAIETREPEAA
>NZ_CP015736.1|WP_064332520.1|2044565_2046878_+|NADP-dependent-malic-enzyme
MSTGDKSRTQDGPASGDIDQQALFFHRHPRPGKLEINPTKPLGNQRDLALAYSPGVAAPCIAIRDDPQTAADYTARANLVAVVSNGTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIEIDAPTVDEMVSVVSALEPTFGGINLEDIKAPECFEVERQLREKMDIPVFHDDQHGTAIIVAAAVLNGLELAGKALSDAKIVASGAGAAALACLNQLVSLGAKVENIWVHDIEGVVYKGREALMDQWKSVYAQETDKRQLSETIDDADVFLGLSAAGVLKPELLARMAEKPLIMALANPTPEIMPEEARAARPDAMICTGRSDFPNQVNNVLCFPYIFRGALDCGARTINEEMKMAAVRAIASLAREEVSDVAARAYSGETPSFGPNYLIPSPFDQRLILRIAPAVARAAAETGVATRPITDFDAYLDQLNRFVWRSGFIMKPIFAAAKNAAKKRVIFAEGEDERVLRAAQVLLEEDIAKPILIGRPQIIETRLKRYGLRIRPQADFEVVNPEDDPRYRDYVDDYFRIVGRRGVIPEAARTIVRTNQTVIGALALKRGEADALICGVEGRYAKHLRDVSQIIGKKEGVLDFSALSLLISQRGATFFTDTYVTFDPTAEEVAQMTVMAAQEIRRFGITPRAALVSHSNFGSRDSDSAFKMRRAMEMVHEMDPTLEADGEMHGDAAISEALRQRVMPNSTLSGEANLLVFPNLDAANITLGVVKTMTDSLHVGPILLGAAMPAHILSPSVTSRGVVNMAALAVVEASNPA
>NZ_CP015736.1|WP_064330248.1|2046995_2047358_-|helix-turn-helix-transcriptional-regulator
MKDLVSRCPIEEVMQVLSGRWPTLLIYYLKDGTKRFSDLRRDNPTVSHRILTLELRKLEKAGIVRRTVFDGYPLRVEYDLTPSGLTLLPLVDALGDWWEARDARRPAPQMKTAAEAAAVS

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Crispr_ID: NZ_CP015736_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015736_4

2089142-2089239

Orphan

Consensus_repeat	Method
CGCTGCTTCTTGCTGCGCTCCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP015736_4

>merge|NZ_CP015736|4|2089142-2089239|CRISPRCasFinder
CGCTGCTTCTTGCTGCGCTCCTCACGCGCCTTCTGCTGCTCGTCCTGCCGGCGCTGTTCTTCCCGCTCGGCGTCACGCTGCTTCTTGCGGCGCTCCTC

>NZ_CP015736|4|4|2089142-2089239|CRISPRCasFinder
CGCTGCTTCTTGCTGCGCTCCTC	ACGCGCCTTCTGCTGCTCGTCCTGCCGGCGCTGTTCTTCCCGCTCGGCGTCA
CGCTGCTTCTTGCGGCGCTCCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015736.1\|WP_064330278.1\|2086639_2087275_+\|molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl\|CDD\|234725
NZ_CP015736.1\|WP_064330272.1\|2078470_2080294_-\|potassium-transporter	unknown	unknown	gnl\|CDD\|235131
NZ_CP015736.1\|WP_064330290.1\|2099134_2099917_+\|adenosylcobinamide-GDP-ribazoletransferase	unknown	unknown	gnl\|CDD\|234697
NZ_CP015736.1\|WP_064330287.1\|2096258_2097074_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|227310
NZ_CP015736.1\|WP_064330286.1\|2095400_2096129_-\|DUF2270-domain-containing-protein	unknown	unknown	gnl\|CDD\|227817
NZ_CP015736.1\|WP_064330285.1\|2095120_2095387_+\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|227712
NZ_CP015736.1\|WP_064330276.1\|2082647_2085191_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NZ_CP015736.1\|WP_064330271.1\|2077845_2078340_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP015736.1\|WP_064330277.1\|2085575_2086484_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_CP015736.1\|WP_064330273.1\|2080351_2080726_-\|DUF971-domain-containing-protein	unknown	unknown	gnl\|CDD\|226066
NZ_CP015736.1\|WP_064330270.1\|2076889_2077798_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|378820
NZ_CP015736.1\|WP_064330281.1\|2089997_2092052_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|225439
NZ_CP015736.1\|WP_064330283.1\|2093344_2094148_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226670
NZ_CP015736.1\|WP_064330274.1\|2080867_2081914_+\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|237364
NZ_CP015736.1\|WP_064330282.1\|2092392_2093175_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270420
NZ_CP015736.1\|WP_064330284.1\|2094144_2094975_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226634
NZ_CP015736.1\|WP_064330289.1\|2097694_2098711_-\|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234636
NZ_CP015736.1\|WP_064330279.1\|2087271_2087793_+\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|367391
NZ_CP015736.1\|WP_145925898.1\|2081936_2082584_+\|DUF1176-domain-containing-protein	unknown	unknown	gnl\|CDD\|369032
NZ_CP015736.1\|WP_064330288.1\|2097216_2097594_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|260133

Protein	Function_ID	Function_description	E-value
NZ_CP015736.1\|WP_064330278.1\|2086639_2087275_+\|molybdenum-cofactor-guanylyltransferase	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	6.85867e-60
NZ_CP015736.1\|WP_064330272.1\|2078470_2080294_-\|potassium-transporter	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
NZ_CP015736.1\|WP_064330290.1\|2099134_2099917_+\|adenosylcobinamide-GDP-ribazoletransferase	gnl\|CDD\|234697	PRK00235, cobS, cobalamin synthase; Reviewed.	1.63963e-53
NZ_CP015736.1\|WP_064330287.1\|2096258_2097074_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|227310	COG4976, COG4976, Predicted methyltransferase (contains TPR repeat) [General function prediction only].	2.4281e-134
NZ_CP015736.1\|WP_064330286.1\|2095400_2096129_-\|DUF2270-domain-containing-protein	gnl\|CDD\|227817	COG5530, COG5530, Predicted integral membrane protein [Function unknown].	3.27584e-98
NZ_CP015736.1\|WP_064330285.1\|2095120_2095387_+\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|227712	COG5425, COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase [Amino acid transport and metabolism].	7.97801e-54
NZ_CP015736.1\|WP_064330276.1\|2082647_2085191_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	4.61492e-59
NZ_CP015736.1\|WP_064330271.1\|2077845_2078340_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	9.58421e-19
NZ_CP015736.1\|WP_064330277.1\|2085575_2086484_+\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	8.92928e-13
NZ_CP015736.1\|WP_064330273.1\|2080351_2080726_-\|DUF971-domain-containing-protein	gnl\|CDD\|226066	COG3536, COG3536, Uncharacterized protein conserved in bacteria [Function unknown].	3.14912e-67
NZ_CP015736.1\|WP_064330270.1\|2076889_2077798_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	2.1953e-12
NZ_CP015736.1\|WP_064330281.1\|2089997_2092052_-\|OmpA-family-protein	gnl\|CDD\|225439	COG2885, OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane].	9.68203e-29
NZ_CP015736.1\|WP_064330283.1\|2093344_2094148_+\|ABC-transporter-permease	gnl\|CDD\|226670	COG4215, ArtQ, ABC-type arginine transport system, permease component [Amino acid transport and metabolism].	3.89237e-94
NZ_CP015736.1\|WP_064330274.1\|2080867_2081914_+\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|237364	PRK13361, PRK13361, GTP 3',8-cyclase MoaA.	0
NZ_CP015736.1\|WP_064330282.1\|2092392_2093175_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270420	cd13702, PBP2_mlr5654_like, Substrate binding domain of ABC-type histidine/lysine/arginine/ornithine transporter-like; the type 2 periplasmic-binding protein fold. This group includes uncharacterized periplasmic substrate-binding protein similar to HisJ and LAO proteins which serve as initial receptors in the ABC transport of histidine-, arginine, and lysine-arginine-ornithine amino acids. This group belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.28793e-129
NZ_CP015736.1\|WP_064330284.1\|2094144_2094975_+\|ABC-transporter-permease	gnl\|CDD\|226634	COG4160, ArtM, ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism].	4.51473e-104
NZ_CP015736.1\|WP_064330289.1\|2097694_2098711_-\|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase	gnl\|CDD\|234636	PRK00105, cobT, nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Reviewed.	4.64582e-156
NZ_CP015736.1\|WP_064330279.1\|2087271_2087793_+\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|367391	pfam03205, MobB, Molybdopterin guanine dinucleotide synthesis protein B. This protein contains a P-loop.	1.04815e-72
NZ_CP015736.1\|WP_145925898.1\|2081936_2082584_+\|DUF1176-domain-containing-protein	gnl\|CDD\|369032	pfam06674, DUF1176, Protein of unknown function (DUF1176). This family consists of several hypothetical bacterial proteins of around 340 residues in length. Members of this family contain six highly conserved cysteine residues. The function of this family is unknown.	5.79847e-10
NZ_CP015736.1\|WP_064330288.1\|2097216_2097594_-\|diacylglycerol-kinase	gnl\|CDD\|260133	cd14264, DAGK_IM, Integral membrane diacylglycerol kinase. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of diacylglycerol to phosphatidic acid. Escherichia coli DAGK participates in the membrane-derived oligosaccharide cycle (MDO cycle) by recycling lipids to restore phosphatidylglycerols that were used up in the biosynthesis of MDOs. DAGK also recycles diacylglycerols that are produced during the biosynthesis of lipopolysaccharides (LPS) back to phospholipids. DAGK is not the main source of phosphatidic acid in de-novo biosynthesis of glycerophospholipids. Escherichia coli DAGK has low activity as an undecaprenol kinase.	4.83421e-33

>NZ_CP015736.1|WP_064330279.1|2087271_2087793_+|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MTRPKIFGIAGWKNSGKTGLAVRLVSELVARGYRVSTIKHAHHDFDIDKVGADSYRHRQAGAHEVTIVSGTRYAIMHELRGAPEPSFEEILARLAPCDLVLIEGYKREPIPKIEARRLEAANRTPLAPEDPHITAIAADHPVPDAGLPVFDLDDTATIADFVVAVTGLKTPEH
>NZ_CP015736.1|WP_064330278.1|2086639_2087275_+|molybdenum-cofactor-guanylyltransferase
MTATHAIVGVILAGGLSSRMGQDKARIRLGGAALIDRAARRLKPQVSAVAVNANGPVLFERGEELPVFADLDAARAGPLGGVLAALDYARRHHPEASHVATVPTDSPFFPTDLVARLSRVVDTPERIAVARSVSGLHPVFALWPVTLATDLAEWLAGGGALRVRSYLERHQAREITFPLIETSRGEFDPFFNINTPDDLDEAENWLWVLER
>NZ_CP015736.1|WP_064330277.1|2085575_2086484_+|DMT-family-transporter
MTTTANAKGALFMAIAMIGFTCNDALVKSVTGDMNTGQILFVRGLMTTVLVVAIARWMGALGSWRIVLQPAVALRIAAEILASLAYVSALGAMPLANTASILQALPLAVTLGAALFLNEKVGWRRWLAIIAGFAGVLIVIRPGPEGFSLAAVYVIASVVGAAARDLCTRRIDRSVPSLFISVITAASITVTGAVMIVPMGGWQPVSGEAFVRLAAASVLLLVGYQTIVIAMRTGEISFIAPFRYTSLIWAIAIGFLFFGEVPDFWMTVGVGIIVASGLYTFYRENRRRDVEAVAQESKPESP
>NZ_CP015736.1|WP_064330276.1|2082647_2085191_-|methyl-accepting-chemotaxis-protein
MSFIDRLLQQRRIVTKVLLFVIPLVALIAGIGLVGYFTASTLNGHMTVTRETINSLSHFQNLRTGLQDFVDRPGEATRAALGARIDEQEAGINDLDALLPDAAEKAKIASVVALAGTMREQSETLWSIDQERNAVTAGLEEALATMAKDGAFAEKQIGVIRNESGEKEAFAKALLFDAAAYQGLAERIGKFRKPVALAMKAEDKVKAAETYLPQLLKQLDESRAIASPKALEQIKPFEAELAKVKDILAGSDDAEAKKTKFVPVLTKLSKFDADFLKEAGKNSDTAAKRFVGMDAEIALLKTLITLMGDTFKGIDETRLHISELHRKLDQPSRDAVLADVKAVAGSAAELAKLGTKNAALRDLSQKLAPSLARIEQGTQDLISVGEKWQAARAAAYASVADASQTLEQFVSSAQEAGKKDSQRSANVSIIAMVAGTLLAIIGGLMLVETLRGPLKRVTEAMSRLASGDLDISIDGRNRGDEIGDMVRSVAVFRDAARENIRLEQEAEAQRQMTAEEQARRASEQARIEAEQTEALTALSDVLGQLAAGNLEESMTEALAAEYVAMARTYNNAVEALRVTLSDVRATTMEINGGTGNLATSADDLARRTEQQAAALEESSRALRQLTDIVRSTAESAQKTAVSVDETHSYAKRSGEVVAKAVDAMGEINRSSEKISTIIGVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRELAQRCAGAAREIKGLISDSSAQVRNGVALVTETGEALTVINEHISSIHALVGQIEAAAAAQYDGINEVNQAVHQVELITQQNAAMVEENTAEIHGLRHRVEVLNQKIDHFKTRDLDTREGGYYGQHHAA
>NZ_CP015736.1|WP_145925898.1|2081936_2082584_+|DUF1176-domain-containing-protein
MNVLPALLPALLVAALPSLGLAAERPEGIAAAEAVARAALGADCDMNGMEDVPMVGPEAEGFGHALYRFAYKPGYDPNGPDIEAELYQLFCGSGAYNIRNAFVLKTGNSDTPKLIAFATPDLAYEYANGENSRLTAEPKIRGFRATALLVNASFDEKTRTITSHTAWRGIGDAWDSGEWVFRNGDFTLTRFEFDPTYGDPDPTVPESYVVYEAGK
>NZ_CP015736.1|WP_064330274.1|2080867_2081914_+|GTP-3',8-cyclase-MoaA
MNSYAGPLGGANPIAQSDAPMIDPFGRAITYLRVSVTDRCDFRCTYCMAENMTFLPKKDLLTLEELNRLCSTFIAKGVRKLRLTGGEPLVRKNIMHLVRELGRQVHDGRLDELTLTTNGSQLARHAAELADCGVRRINVSLDTLDAQKFRTITRWGDLSKVLEGIDAAQAAGLHIKINAVALKDFNDREIPDLMRWAHGRGMDLTLIETMPMGEIEEDRTDRYMPLSEMRARLEDDFTLTENAYRTGGPARYVTVAETGGRLGFITPMTHNFCESCNRVRLTCTGTLYMCLGQNDAADLRLPLRASDDDALLSQAIDEAITRKPKGHDFVIDRRNRPAVARHMSVTGG
>NZ_CP015736.1|WP_064330273.1|2080351_2080726_-|DUF971-domain-containing-protein
MSDLWPTELRVTKDRQRLVVTFNDGARFDLSAELLRVLSPSAEVQGHGPGQKVTVPGKRNVAIISMTPTGNYAVRIGFDDLHDTGIYTWSYLRELGEKGAELFAAYERELAEKGMSRDISEKPR
>NZ_CP015736.1|WP_064330272.1|2078470_2080294_-|potassium-transporter
MAGEANANDLTQVVVLLAAGVAAVPVFKKIGLGSVLGYLAAGLVIGPFGLGFFADPQAIIHVAELGVVMFLFIIGLEMQPSRLWGMRKDIFGLGAIQVMGAMAALTGIGVSMGFPLIPSFVAGTGFVLTSTAIVMQMLQERGTMSTLKGQRIIAILLFEDLAIVPLLAIVTLLGTGAAATDASDRWLSIGIAIGAIVALVLAGRYLLNPLFRVLAASGAREVMTAAALLVVLGSALAMQVSGLSMAMGAFLAGVLLSESSFRHQLEADIEPFRGILLGLFFLGVGMAIDLGVIAANWQLVVASVVGYMIAKLLLIYVVARLLGTCHAESLERAVLMAQGGEFAFVLYAAAVSAGILNGEENAILTATIIISMVLTPLMVILHDRIVPKQQPSTEGLTLPENVEGTVLMIGFGRFGQIVSQPLLARGYTLSLIDKDAEFVRDAADFGFKVYYGDGARIDILHAAGASTAKAILICLDDKAAAVKIAEIVREEFPLVPILARAYDRGHAVDLVHAGVDFQIRETFESAMVFSRETLKALGEDEDLAAEVVEEFRDVDRERLELEMVGGIYAGRQLIRGNAQPADIVAARTARERAAEEERHRREQEEAS
>NZ_CP015736.1|WP_064330271.1|2077845_2078340_+|winged-helix-turn-helix-transcriptional-regulator
MNKNQAFPWDHPRFRSWIGVGRACQLMQQAMGRAIADLGIKPPHLDILINLYRFDGISQQDLARKLLVGRSNMSMLLPQLEKRGLIERRADAKDKRVLRLSLTGTGRSLTEEAMAIQTGLIDRTLSQAPAERCLAVAEAMEDIIRILQTMESDEPDDTPLAKFR
>NZ_CP015736.1|WP_064330270.1|2076889_2077798_-|alpha/beta-fold-hydrolase
MASFGLKVIRLALSGVARISPDAAGRAAFRLFATTPGRRPRTAKEKELFARSEGWMRQAERVPLAFAGGRAVAHRFAARPCQSFSGRVLVVHGWGSRAAYLTALTEALVAAGHEVVALDLPGHGASGGRTLTLPMAVRAIDAAWQRFGGFDYFCGHSFGGASLACAASGLVPSVPAHRPRRLVTIGSPSEMTWLFKDLGRFLKLGPKAQVALENHVERIAGAPLSAFDAANGAGRLKSPMLVLHAQDDKEVPALHARRYAAAGPNVTLEWANGFGHRRIVSAEPVIDRIVQFLAEDAARIAA
>NZ_CP015736.1|WP_064330281.1|2089997_2092052_-|OmpA-family-protein
MTFRSRLFATVALPVLSTALIATPALADALMKPFEVAQESTGEGQPSEEELLLQQQQQQQDEAERAAEEEKQRQAEEQKAAEEAERAAAEEKAAEEEAQRAAAEEQKAAEEAERAAAEEKAAEDEAQRAAAEEEQRQAEEQQAAEEAEKAAAEQRAAEDEAQRAAAEAEQQRQADERQAAEEQNAQEEQTPAEEQQAEQPAQQPDGGASQTTAGEQPAAGEDEQPAIVETPAETGTDQPATAETGETPAAEPVPDIVDTMSEEEKQEIAEDPARTDETVVLPVENGAAVLDSDKDADNAGGQTSREDRRRKREELRAQEEEVPVPDTDDAAQATISEEVREAVPGRIEAAIREEGQRVDAAPDFAVPETTNIINNTVINNTVINNNTVNNTTIDNSTTKVNIVERFENRTVLEVGDRLIVRGDDRPRLRRDSEEVYYDNLARGRVRETIVRPGGVRIVTIYNRYGDIIQRSRVGLDGREYILVYAPELEDDSPRPGLVDIGYELPPMRLRIPVSDYIIDTSSNPDRDYYDFLAEPPVERVERVYTIDEVKHSARLRDKVRRIDLDTITFATGSADVPMSQARTLRSVAEAMQKVLDRDPGETFLIEGHTDAVGSDASNLVLSDERAESVASLLTDVYGIPPENLQTQGYGERFLKVKTQIAEQQNRRVTIRRVTTLVRPMARAN
>NZ_CP015736.1|WP_064330282.1|2092392_2093175_+|ABC-transporter-substrate-binding-protein
MRISKRFTLAASAAVIALFASSAMAEGEKIVIGTEGAYPPFNNLESDGTLTGFDIDIAKALCEEMKAECTFVTQDWDGIIPALIAKKFDAIIASMSITAERKEKVDFSKKYYNTPPAIVVPKDSEITEATPEALAGKTLGAQGSTTHSNYAEAHMKDAEVKLYPTADEYKLDIANGRIDAVVDDVVVLSEWLKSDDGACCKLLGTLPVDPVINGEGAGIAVRKGETELADKFTAAIAAIRASGKYQEINAKYFPFDVYGD
>NZ_CP015736.1|WP_064330283.1|2093344_2094148_+|ABC-transporter-permease
MSGFFTAIVEAVSAILGIIDPLCGPIGIFNLFAGGTLLACGNAGWGDEIAFGFLVTASLAIATLPVGLVAGFFIALAKQSEEKSLRLSANIYTTLFRGLPELLTLFIVYYGLQILVQNLAAALGYGGAVEINAFFAGMIALGVVFSAYCSEVLLSAFKAIPRGQYEAGYALGLHHGRTMRLIVLPQLIRVALPGLGNLWMALLKDTALVSVIGLPDILRQTGVAARVTKEAFQFYAIACLLFLVLAFLSSLVFSAIEGWAKRSEVAR
>NZ_CP015736.1|WP_064330284.1|2094144_2094975_+|ABC-transporter-permease
MSVVTTLIPPQAPPETPPKPFTASRFFGNIFMGVWLALTVGVFLMIVGGWDPEKFTRYGPSYLSGLGVTLLLVGLSVVLGGLISLPLAFARMSKNPVFSWLAYGYVYFFRGTPLLTQLFLVYYGLGSFSAELKAWGLWWFFRDAWNCALLTFTLNTAAYQAEILRGAIESVPRGQHEGADALGLPKKVAFFKVILPQALIVALRPYGNEIILMIKGSAIVAIVTVFDLMGETRRAFSRTFDYQAYLWAALLYLLMVELLRNLWAWLELRLTRHLKR
>NZ_CP015736.1|WP_064330285.1|2095120_2095387_+|aspartate-semialdehyde-dehydrogenase
MTNDMAMQLKGYGMTTAQILYRMPDHPQLLQTYIWQHYDLAPDFPEMKSFLKFWQEKLDGPLHSVRYVHRRLISATEWRALKGEFILN
>NZ_CP015736.1|WP_064330286.1|2095400_2096129_-|DUF2270-domain-containing-protein
MPADTPPFPLSTDTKRTGSPALPATPVETINTMVHYYRGELGRMAGWRDRIDRTSNWAITVVAALLSVSLSTPTSHHGVLLFAILLVSLLLMIEARRYRFFDVYRARVRQLERFYFAEILNPRATLDRDWAAPIAKSLRKPEFLISYRDAACRRLRRNYCWLYLILLLAWALKISSSMMQRPATAGKDMTLAFEHVVANAALGPVPGGVVIALVLLFYAAVLYFSLKVDMSDSELSHGSVHV
>NZ_CP015736.1|WP_064330287.1|2096258_2097074_+|methyltransferase-domain-containing-protein
MKKIDEDALAEAYNRALSLEKSGDFDAAAKAYAEVLALDPDDHGGAAVRLAAMGRGDTPEKAPDAYVTTLFDQHAEVFDNVLVDQLGYCVPLTVRQRFQALGIGPFKRVLDLGCGTGLTGGALRDMAEDITGIDLSENMVEIAHDKDLYETLYVAEAVDFLDDNEEEPFDLITATDVLPYLGALEPLFFGAAENLLPGGHFIFSSETLPDATFAGRPFMVGPHQRFAHAAAYVRQRLEETGFDIVEITDITVRLEEGEPIPGHLVLAKYRG
>NZ_CP015736.1|WP_064330288.1|2097216_2097594_-|diacylglycerol-kinase
MGQAPIEKKTGISHLFAAATYSAAGARRLLGESAFRHELIAFGVAMVLFAVVGASFFQYVAMAILFLLMIAFEALNTAIEEIVDRVSPEISEMGKHSKDLGSFAVFCLIVANAVYAGYVVASKFI
>NZ_CP015736.1|WP_064330289.1|2097694_2098711_-|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase
MSASGLPFDDFRELLRNLPGPDSAALVAARERDRQLTKPPGALGRLEEIAFWLAAWTGRPPAVTRPLVAIFAGNHGVTKQGITPYPSSVTAQMVENFAAGGAAINQICVTHDLGLKVFDLALDYPTADITEEAALSERDCAATMAFGMEAVAGGTDLLCIGEMGIGNTTIAAAINLALYGGTAEEWVGPGTGSEGAVLERKVAAVKKAVDLHRAHLSDPLEVLRRLGGREIAAMAGAILAARMQKIPVILDGYVATAAGAILRAANPAALDHCLIGHVSAEPGHLKSIEKLGKTPLLALGMRLGEGTGAALAAGIVKAAAACHSGMATFVQAGVSNRT
>NZ_CP015736.1|WP_064330290.1|2099134_2099917_+|adenosylcobinamide-GDP-ribazoletransferase
MAIQDYIDDTARSVAFLSRVPVPQRHFIGHDGRLSRAVRAFPLAGVLIVLPAAALAALLSAFHAPPLLVAFATLAVQVLVTGALHEDGLSDSADGIGGGRDRESALAIMKDSRIGSYGAVALILSFGLRAAAIAALAAALSPSGLGMALLAVAAASRTAMVWHWSLLPPARQGGVAASVGEPDGGATIVALASGILLASALLLPHGSVLALVLALVLAVAAVIAFNRLALGKIGGHTGDTIGATQQLAEMSVLFALALAL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	1199529-1199558	5	0.833
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2565167-2565196	5	0.833
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_AP014802	Rhodovulum sulfidophilum plasmid Plasmid2 DNA, complete genome, strain: DSM 2351	81430-81459	5	0.833
NZ_CP015736_1	1.2\|972370\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972370-972399	30	NZ_CP015530	Rhodococcus sp. WB1 plasmid pWB1, complete sequence	113311-113340	6	0.8
NZ_CP015736_1	1.6\|972634\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972634-972663	30	NC_020543	Sphingomonas sp. MM-1 plasmid pISP2, complete sequence	40983-41012	6	0.8
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	KT809302	Haloarcula californiae icosahedral virus 1, complete genome	17429-17458	6	0.8
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	271986-272015	6	0.8
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	214680-214709	6	0.8
NZ_CP015736_1	1.13\|973096\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973096-973125	30	NZ_CP010886	Vibrio parahaemolyticus strain CHN25 plasmid P2, complete sequence	63887-63916	6	0.8
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_CP030100	Roseovarius sp. AK1035 plasmid unnamed, complete sequence	141449-141478	6	0.8
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_CP045385	Ruegeria sp. THAF33 plasmid pTHAF33_a, complete sequence	181773-181802	6	0.8
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_CP020475	Roseovarius mucosus strain SMR3 plasmid pSMR3-1, complete sequence	135343-135372	6	0.8
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	MT657339	Gordonia phage SpeedDemon, complete genome	81672-81701	6	0.8
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NC_031074	Gordonia phage Bantam, complete genome	78578-78607	6	0.8
NZ_CP015736_1	1.1\|972304\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972304-972333	30	KX657793	Mycobacterium phage DarthPhader, complete genome	48364-48393	7	0.767
NZ_CP015736_1	1.1\|972304\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972304-972333	30	NZ_CP010856	Marinovum algicola DG 898 plasmid pMaD1, complete sequence	36397-36426	7	0.767
NZ_CP015736_1	1.1\|972304\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972304-972333	30	NZ_CP018081	Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence	230639-230668	7	0.767
NZ_CP015736_1	1.2\|972370\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972370-972399	30	NZ_CP012886	Mycobacterium chimaera strain AH16 plasmid unnamed1, complete sequence	248712-248741	7	0.767
NZ_CP015736_1	1.5\|972568\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972568-972597	30	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	79267-79296	7	0.767
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NC_014753	Oceanithermus profundus DSM 14977 plasmid pOCEPR01, complete sequence	52837-52866	7	0.767
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NC_023286	Streptomyces sp. F12 plasmid pFRL6, complete sequence	83099-83128	7	0.767
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	KY555145	Caulobacter phage Ccr29, complete genome	49406-49435	7	0.767
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	KY555143	Caulobacter phage Ccr2, complete genome	44873-44902	7	0.767
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NC_019407	Caulobacter phage CcrMagneto, complete genome	43665-43694	7	0.767
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	KY555142	Caulobacter phage Ccr10, complete genome	44398-44427	7	0.767
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NC_019411	Caulobacter phage CcrSwift, complete genome	43627-43656	7	0.767
NZ_CP015736_1	1.8\|972766\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972766-972795	30	NZ_CP017243	Rhizobium etli 8C-3 plasmid pRsp8C3b, complete sequence	7722-7751	7	0.767
NZ_CP015736_1	1.8\|972766\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972766-972795	30	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	240380-240409	7	0.767
NZ_CP015736_1	1.9\|972832\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972832-972861	30	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	380306-380335	7	0.767
NZ_CP015736_1	1.11\|972964\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972964-972993	30	NZ_CP029835	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed5, complete sequence	2450-2479	7	0.767
NZ_CP015736_1	1.12\|973030\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973030-973059	30	NZ_CP030242	Moraxella bovis strain Epp63 (300) plasmid pMBO-1, complete sequence	3225-3254	7	0.767
NZ_CP015736_1	1.12\|973030\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973030-973059	30	NC_010893	Moraxella bovis Epp63 plasmid pMBO-1, complete sequence	3224-3253	7	0.767
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_CP020371	Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs417, complete sequence	105654-105683	7	0.767
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_CP010860	Marinovum algicola DG 898 plasmid pMaD5, complete sequence	117580-117609	7	0.767
NZ_CP015736_1	1.1\|972304\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972304-972333	30	NZ_CP018096	Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence	416492-416521	8	0.733
NZ_CP015736_1	1.1\|972304\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972304-972333	30	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	812591-812620	8	0.733
NZ_CP015736_1	1.1\|972304\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972304-972333	30	MN317029	Aeromonas phage vB_AhyS-A18P4, complete genome	2694-2723	8	0.733
NZ_CP015736_1	1.3\|972436\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972436-972465	30	MF919515	Propionibacterium phage Leviosa, complete genome	8466-8495	8	0.733
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NZ_CP042998	Aquisphaera giovannonii strain OJF2 plasmid pOJF2_1, complete sequence	97692-97721	8	0.733
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NZ_LR134468	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 26, complete sequence	84559-84588	8	0.733
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NZ_CP033873	Caulobacter sp. FWC26 plasmid p1, complete sequence	132042-132071	8	0.733
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NC_007431	Streptomyces venezuelae pSVH1 plasmid	11724-11753	8	0.733
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NZ_CP029835	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed5, complete sequence	259258-259287	8	0.733
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	MG962371	Mycobacterium phage LaterM, complete genome	6818-6847	8	0.733
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	KM677211	Mycobacterium phage Murucutumbu, complete genome	6812-6841	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP024200	Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence	637349-637378	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	CP026798	Shigella boydii strain NCTC 9353 plasmid unnamed, complete sequence	8555-8584	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	CP026844	Shigella boydii strain NCTC 9733 plasmid unnamed, complete sequence	6411-6440	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026767	Shigella boydii strain 59-248 plasmid unnamed	141887-141916	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026813	Shigella boydii strain 83-578 plasmid unnamed, complete sequence	85792-85821	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026794	Shigella flexneri strain 74-1170 plasmid unnamed	29995-30024	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP033511	Shigella flexneri strain 2016AM-0877 plasmid p2016AM-0877, complete sequence	215190-215219	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026099	Shigella flexneri strain FDAARGOS_74 plasmid unnamed	147447-147476	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026812	Shigella flexneri strain 64-5500 plasmid unnamed, complete sequence	37322-37351	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026826	Shigella dysenteriae strain ATCC 12021 plasmid unnamed	184184-184213	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	CP046677	Escherichia coli strain 152661 plasmid p152661_pINV, complete sequence	132631-132660	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NC_017319	Shigella flexneri 2002017 plasmid pSFxv_1, complete sequence	88859-88888	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP012142	Shigella flexneri 4c strain 1205 plasmid 1205p2, complete sequence	87525-87554	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026800	Shigella flexneri strain NCTC 9728 plasmid unnamed, complete sequence	28373-28402	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NC_002698	Shigella flexneri 5a virulence plasmid pWR501, complete sequence	83444-83473	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP011417	Escherichia coli strain CFSAN029787 plasmid pCFSAN029787_01, complete sequence	253600-253629	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP007038	Shigella flexneri G1663 plasmid pG1663, complete sequence	89383-89412	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP030773	Shigella flexneri 1c strain Y394 plasmid pINV-Y394, complete sequence	87063-87092	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP020087	Shigella flexneri 1a strain 0670 plasmid unnamed1, complete sequence	185472-185501	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP050866	Escherichia coli strain 8-3-Ti3 plasmid unnamed1, complete sequence	115177-115206	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP050863	Escherichia coli strain 8-3-DC15 plasmid unnamed1, complete sequence	115176-115205	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP020337	Shigella flexneri 4c strain 1602 plasmid unnamed1, complete sequence	53016-53045	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NC_010660	Shigella boydii CDC 3083-94 plasmid pBS512_211, complete sequence	40262-40291	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP045942	Shigella flexneri 2a strain AUSMDU00010535 plasmid pAUSMDU00010535_01, complete sequence	106100-106129	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NC_004851	Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence	90200-90229	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	CP054891	Shigella flexneri strain FDAARGOS_713 plasmid unnamed1, complete sequence	84379-84408	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026804	Shigella flexneri strain 89-141 plasmid unnamed1	43036-43065	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP034059	Shigella flexneri strain FDAARGOS_535 plasmid unnamed1, complete sequence	167410-167439	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP024476	Shigella flexneri 7b strain 94-3007 plasmid unnamed3, complete sequence	196370-196399	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_LR213456	Shigella flexneri strain AUSMDU00008332 isolate AUSMDU00008332 plasmid 2	72580-72609	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026771	Shigella flexneri Y strain 93-3063 plasmid unnamed3, complete sequence	24803-24832	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP044157	Shigella flexneri strain AR-0424 plasmid pAR-0424-2, complete sequence	201312-201341	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026763	Shigella boydii strain NCTC 9850 plasmid unnamed	96842-96871	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026876	Shigella boydii strain ATCC 35964 plasmid unnamed, complete sequence	90613-90642	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026837	Shigella boydii strain ATCC 49812 plasmid unnamed, complete sequence	110120-110149	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026796	Shigella boydii strain ATCC BAA-1247 plasmid unnamed	148864-148893	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP044154	Shigella flexneri strain AR-0425 plasmid pAR-0425-2, complete sequence	218320-218349	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP034933	Shigella flexneri strain 2013C-3749 plasmid p2013C-3749-2, complete sequence	35573-35602	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP037924	Shigella flexneri 5a str. M90T plasmid pWR100, complete sequence	5825-5854	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP037924	Shigella flexneri 5a str. M90T plasmid pWR100, complete sequence	219316-219345	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NC_007608	Shigella boydii Sb227 plasmid pSB4_227, complete sequence	35651-35680	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP041512	Shigella boydii strain KCCM 41690 plasmid unnamed, complete sequence	80544-80573	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP027028	Shigella dysenteriae strain E670/74 plasmid unnamed, complete sequence	43804-43833	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NC_019197	Shigella flexneri plasmid pSF5, complete sequence	86901-86930	8	0.733
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP026830	Shigella dysenteriae strain ATCC 12039 plasmid unnamed, complete sequence	16357-16386	8	0.733
NZ_CP015736_1	1.13\|973096\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973096-973125	30	NC_013448	Nocardia aobensis plasmid pYS1, complete sequence	2694-2723	8	0.733
NZ_CP015736_1	1.13\|973096\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973096-973125	30	NC_017791	Deinococcus gobiensis I-0 plasmid P2, complete sequence	81824-81853	8	0.733
NZ_CP015736_1	1.14\|973162\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973162-973191	30	NC_015708	Pseudoalteromonas sp. SANK 73390 plasmid pTML1 carrying thiomarinol biosynthesis cluster	68936-68965	8	0.733
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1221719-1221748	8	0.733
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NZ_CP005085	Sphingobium sp. TKS plasmid pTK1, complete sequence	258336-258365	8	0.733
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	JX403939	Pseudomonas phage YMC/01/01/P52_PAE_BP, complete genome	28600-28629	8	0.733
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NC_042342	Pseudomonas virus H66, complete genome	16240-16269	8	0.733
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	KU310943	Pseudomonas phage YMC11/07/P54_PAE_BP, complete genome	43899-43928	8	0.733
NZ_CP015736_1	1.1\|972304\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972304-972333	30	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	806585-806614	9	0.7
NZ_CP015736_1	1.3\|972436\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972436-972465	30	NC_022050	Paracoccus aminophilus JCM 7686 plasmid pAMI8, complete sequence	53110-53139	9	0.7
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	844725-844754	9	0.7
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	446494-446523	9	0.7
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	103750-103779	9	0.7
NZ_CP015736_1	1.7\|972700\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972700-972729	30	NC_011143	Phenylobacterium zucineum HLK1 plasmid, complete sequence	59059-59088	9	0.7
NZ_CP015736_1	1.9\|972832\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972832-972861	30	NZ_CP041074	Bacillus tropicus strain LM1212-W3 plasmid p1, complete sequence	865-894	9	0.7
NZ_CP015736_1	1.9\|972832\|30\|NZ_CP015736\|CRISPRCasFinder,CRT	972832-972861	30	NZ_CP024774	Bacillus thuringiensis LM1212 plasmid pLM3, complete sequence	68855-68884	9	0.7
NZ_CP015736_1	1.13\|973096\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973096-973125	30	NC_017771	Deinococcus gobiensis I-0 plasmid P3, complete sequence	172053-172082	9	0.7
NZ_CP015736_1	1.13\|973096\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973096-973125	30	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	20088-20117	9	0.7
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	197985-198014	9	0.7
NZ_CP015736_1	1.10\|972898\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	972898-972927	30	NZ_CP010858	Marinovum algicola DG 898 plasmid pMaD3	85439-85468	10	0.667
NZ_CP015736_1	1.15\|973228\|30\|NZ_CP015736\|CRISPRCasFinder,CRT,PILER-CR	973228-973257	30	MK524524	Streptomyces phage Caelum, complete genome	11839-11868	10	0.667
NZ_CP015736_3	3.5\|2032638\|40\|NZ_CP015736\|CRISPRCasFinder	2032638-2032677	40	NZ_CP003988	Streptomyces sp. 769 plasmid pSGZL, complete sequence	163068-163107	11	0.725

1. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.833

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
cctgatctcgcgcagcggcgtgccggccgg	Protospacer
  .************ ******.*******

2. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 5, identity: 0.833

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
cctgatctcgcgcagcggcgtgccggccgg	Protospacer
  .************ ******.*******

3. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014802 (Rhodovulum sulfidophilum plasmid Plasmid2 DNA, complete genome, strain: DSM 2351) position: , mismatch: 5, identity: 0.833

gacgatctcgcgcaggggcgtgtcggccgg--	CRISPR spacer
gccgatctcgcccaggggcgtgt--gccagcc	Protospacer
* ********* ***********  ***.*

4. spacer 1.2|972370|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP015530 (Rhodococcus sp. WB1 plasmid pWB1, complete sequence) position: , mismatch: 6, identity: 0.8

ttcggatgccgccccgtggcggggcggtca	CRISPR spacer
ggccgatgccgccgcctggcggggcggtga	Protospacer
  * ********* * ************ *

5. spacer 1.6|972634|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_020543 (Sphingomonas sp. MM-1 plasmid pISP2, complete sequence) position: , mismatch: 6, identity: 0.8

acttcgctctgaaggttcgcctgagactgc	CRISPR spacer
acttcgctctcaagcttcgcctgggcccga	Protospacer
********** *** ********.* *.*

6. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to KT809302 (Haloarcula californiae icosahedral virus 1, complete genome) position: , mismatch: 6, identity: 0.8

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
ggagacggcggcctcctcggcggcgacata	Protospacer
...***** ***************** **

7. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 6, identity: 0.8

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
gatgacgcgggccccctcggcggcgaaacg	Protospacer
.* **** *****.**************.

8. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 6, identity: 0.8

aaggacgggggcctcctcggcggcgaaatc---	CRISPR spacer
aaggccgggggcctcct---cggcgagctcccg	Protospacer
**** ************   ******. **

9. spacer 1.13|973096|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010886 (Vibrio parahaemolyticus strain CHN25 plasmid P2, complete sequence) position: , mismatch: 6, identity: 0.8

--aacaatgagggcgcggccttctgggagcac	CRISPR spacer
ccacca--gaaggggcggccttctgggagcaa	Protospacer
  * **  **.** *****************

10. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030100 (Roseovarius sp. AK1035 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
ggcgatctcgcgcagcggcttgtcggaatg	Protospacer
*.************* *** ******   *

11. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045385 (Ruegeria sp. THAF33 plasmid pTHAF33_a, complete sequence) position: , mismatch: 6, identity: 0.8

---gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
ttggtcgg---cgcgcaggggcgtgtcggcggg	Protospacer
   * **.   ******************* **

12. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020475 (Roseovarius mucosus strain SMR3 plasmid pSMR3-1, complete sequence) position: , mismatch: 6, identity: 0.8

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
ggcgatctcgcgcagcggcttgtcggaatg	Protospacer
*.************* *** ******   *

13. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to MT657339 (Gordonia phage SpeedDemon, complete genome) position: , mismatch: 6, identity: 0.8

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
ggagatggtgcgcaggggcgagtcggccgg	Protospacer
*. ***  .*********** *********

14. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_031074 (Gordonia phage Bantam, complete genome) position: , mismatch: 6, identity: 0.8

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
ggagatggtgcgcaggggcgagtcggccgg	Protospacer
*. ***  .*********** *********

15. spacer 1.1|972304|30|NZ_CP015736|CRISPRCasFinder,CRT matches to KX657793 (Mycobacterium phage DarthPhader, complete genome) position: , mismatch: 7, identity: 0.767

caactcgccttcgagcgcctggatacggcg	CRISPR spacer
gaagtcgccttcgagcgcctggatcgagta	Protospacer
 ** ********************  .*..

16. spacer 1.1|972304|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP010856 (Marinovum algicola DG 898 plasmid pMaD1, complete sequence) position: , mismatch: 7, identity: 0.767

caactcgccttcgagcgcctggatacggcg	CRISPR spacer
catgacgccttcgagcacctggatatggtc	Protospacer
**   ***********.********.**.

17. spacer 1.1|972304|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP018081 (Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.767

caactcgccttcgagcgcctggatacggcg	CRISPR spacer
catgacgccttcgagcacctggatatggtc	Protospacer
**   ***********.********.**.

18. spacer 1.2|972370|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP012886 (Mycobacterium chimaera strain AH16 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

ttcggatgccgccccgtggc-ggggcggtca	CRISPR spacer
cgaggatcccgccccgtggcgggggcgatt-	Protospacer
.  **** ************ ******.*.

19. spacer 1.5|972568|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 7, identity: 0.767

ggtggaaaggctgaacatgctgtctcctaa	CRISPR spacer
ggtggaaagcctgaacgtgctgtcctcgcc	Protospacer
********* ******.*******..*

20. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_014753 (Oceanithermus profundus DSM 14977 plasmid pOCEPR01, complete sequence) position: , mismatch: 7, identity: 0.767

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
gacctcgggggcctcctcggcggtgaacgc	Protospacer
.*   ******************.***  *

21. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_023286 (Streptomyces sp. F12 plasmid pFRL6, complete sequence) position: , mismatch: 7, identity: 0.767

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
agtgacgggggcgtcgtcggcggcgaggcc	Protospacer
*. ********* ** **********...*

22. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to KY555145 (Caulobacter phage Ccr29, complete genome) position: , mismatch: 7, identity: 0.767

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
ggcgacggcgggctcctcggcggcgacgtc	Protospacer
.. ***** ** ************** .**

23. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to KY555143 (Caulobacter phage Ccr2, complete genome) position: , mismatch: 7, identity: 0.767

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
ggcgacggcgggctcctcggcggcgacgtc	Protospacer
.. ***** ** ************** .**

24. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_019407 (Caulobacter phage CcrMagneto, complete genome) position: , mismatch: 7, identity: 0.767

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
ggcgacggcgggctcctcggcggcgacgtc	Protospacer
.. ***** ** ************** .**

25. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to KY555142 (Caulobacter phage Ccr10, complete genome) position: , mismatch: 7, identity: 0.767

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
ggcgacggcgggctcctcggcggcgacgtc	Protospacer
.. ***** ** ************** .**

26. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_019411 (Caulobacter phage CcrSwift, complete genome) position: , mismatch: 7, identity: 0.767

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
ggcgacggcgggctcctcggcggcgacgtc	Protospacer
.. ***** ** ************** .**

27. spacer 1.8|972766|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP017243 (Rhizobium etli 8C-3 plasmid pRsp8C3b, complete sequence) position: , mismatch: 7, identity: 0.767

cgggcgagcgagcaatcgctgcggccctcg	CRISPR spacer
ggggcgagggagcaatcgctgccgccgatc	Protospacer
 ******* ************* ***  .

28. spacer 1.8|972766|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 7, identity: 0.767

cgggcgagcgagcaatcgctgcggccctcg	CRISPR spacer
ggaggcggcgcgccatcgctgcggccctcg	Protospacer
 *.*  .*** ** ****************

29. spacer 1.9|972832|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 7, identity: 0.767

ggttccaccatcgccaataggctggccctt	CRISPR spacer
atcctcaccatcgcccataggctggccctg	Protospacer
. ...********** *************

30. spacer 1.11|972964|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029835 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.767

aaggtgaacgtcactgggacgcgcaactgg	CRISPR spacer
aaggtggacgtcactgggacggtcgacgtc	Protospacer
******.**************  *.**

31. spacer 1.12|973030|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030242 (Moraxella bovis strain Epp63 (300) plasmid pMBO-1, complete sequence) position: , mismatch: 7, identity: 0.767

cgggttttcattgatagtctctcctggtgc	CRISPR spacer
tgggttttcattaatagtctcttttgtgtc	Protospacer
.***********.*********..**   *

32. spacer 1.12|973030|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_010893 (Moraxella bovis Epp63 plasmid pMBO-1, complete sequence) position: , mismatch: 7, identity: 0.767

cgggttttcattgatagtctctcctggtgc	CRISPR spacer
tgggttttcattaatagtctcttttgtgtc	Protospacer
.***********.*********..**   *

33. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020371 (Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs417, complete sequence) position: , mismatch: 7, identity: 0.767

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
gtcgatctcgcgcagggccgtgtagggatc	Protospacer
* *************** ***** **

34. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010860 (Marinovum algicola DG 898 plasmid pMaD5, complete sequence) position: , mismatch: 7, identity: 0.767

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
ctcgatctcgcccagcggcgtgtcgtcgcg	Protospacer
  ********* *** ********* *  *

35. spacer 1.1|972304|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP018096 (Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence) position: , mismatch: 8, identity: 0.733

caactcgccttcgagcgcctggatacggcg	CRISPR spacer
catctcgccttcgagcgcgtggagctctgg	Protospacer
** *************** ****  .   *

36. spacer 1.1|972304|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 8, identity: 0.733

caactcgccttcgagcgcctggatacggcg	CRISPR spacer
cacctcgccttcgagcgcgtggagctctgg	Protospacer
** *************** ****  .   *

37. spacer 1.1|972304|30|NZ_CP015736|CRISPRCasFinder,CRT matches to MN317029 (Aeromonas phage vB_AhyS-A18P4, complete genome) position: , mismatch: 8, identity: 0.733

caactcgccttcgagcgcctggatacggcg	CRISPR spacer
aaactcgcctttgagcgcccggatcttggt	Protospacer
 **********.*******.**** . *

38. spacer 1.3|972436|30|NZ_CP015736|CRISPRCasFinder,CRT matches to MF919515 (Propionibacterium phage Leviosa, complete genome) position: , mismatch: 8, identity: 0.733

tccccgccacaagcacggacacgggcgggg	CRISPR spacer
accccgccactagcacggacacgcgtcaaa	Protospacer
 ********* ************ *. ...

39. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP042998 (Aquisphaera giovannonii strain OJF2 plasmid pOJF2_1, complete sequence) position: , mismatch: 8, identity: 0.733

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
ccggacgggggcctcgccggcggcgaggcg	Protospacer
  ************* .*********...

40. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_LR134468 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 26, complete sequence) position: , mismatch: 8, identity: 0.733

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
atcgacgggggcctactcgacggcgagcat	Protospacer
*  *********** ****.******.  .

41. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP033873 (Caulobacter sp. FWC26 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
cggcggcggggcttcatcggcggcgaaatc	Protospacer
 .* .  *****.** **************

42. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_007431 (Streptomyces venezuelae pSVH1 plasmid) position: , mismatch: 8, identity: 0.733

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
cccggcggcggcctcctcggcggcgacctt	Protospacer
   *.*** *****************  *.

43. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP029835 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.733

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
cagcggcacggcctcctcgccggcgaaatc	Protospacer
 ** .  . ********** **********

44. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to MG962371 (Mycobacterium phage LaterM, complete genome) position: , mismatch: 8, identity: 0.733

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
cccgttggtggcgtcctcggcggcgaaata	Protospacer
   * .** *** ****************

45. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to KM677211 (Mycobacterium phage Murucutumbu, complete genome) position: , mismatch: 8, identity: 0.733

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
cccgttggtggcgtcctcggcggcgaaata	Protospacer
   * .** *** ****************

46. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024200 (Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tatcagatcgacgaaaagggcgttggcccg	Protospacer
*.********* ********* *** ..

47. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to CP026798 (Shigella boydii strain NCTC 9353 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

48. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to CP026844 (Shigella boydii strain NCTC 9733 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

49. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026767 (Shigella boydii strain 59-248 plasmid unnamed) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

50. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026813 (Shigella boydii strain 83-578 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

51. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026794 (Shigella flexneri strain 74-1170 plasmid unnamed) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

52. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033511 (Shigella flexneri strain 2016AM-0877 plasmid p2016AM-0877, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

53. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026099 (Shigella flexneri strain FDAARGOS_74 plasmid unnamed) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

54. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026812 (Shigella flexneri strain 64-5500 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

55. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026826 (Shigella dysenteriae strain ATCC 12021 plasmid unnamed) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

56. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to CP046677 (Escherichia coli strain 152661 plasmid p152661_pINV, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

57. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_017319 (Shigella flexneri 2002017 plasmid pSFxv_1, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

58. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012142 (Shigella flexneri 4c strain 1205 plasmid 1205p2, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

59. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026800 (Shigella flexneri strain NCTC 9728 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

60. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_002698 (Shigella flexneri 5a virulence plasmid pWR501, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

61. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011417 (Escherichia coli strain CFSAN029787 plasmid pCFSAN029787_01, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

62. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007038 (Shigella flexneri G1663 plasmid pG1663, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

63. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030773 (Shigella flexneri 1c strain Y394 plasmid pINV-Y394, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

64. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020087 (Shigella flexneri 1a strain 0670 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

65. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050866 (Escherichia coli strain 8-3-Ti3 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

66. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050863 (Escherichia coli strain 8-3-DC15 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

67. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020337 (Shigella flexneri 4c strain 1602 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

68. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_010660 (Shigella boydii CDC 3083-94 plasmid pBS512_211, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

69. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045942 (Shigella flexneri 2a strain AUSMDU00010535 plasmid pAUSMDU00010535_01, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

70. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_004851 (Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

71. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to CP054891 (Shigella flexneri strain FDAARGOS_713 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

72. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026804 (Shigella flexneri strain 89-141 plasmid unnamed1) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

73. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034059 (Shigella flexneri strain FDAARGOS_535 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

74. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024476 (Shigella flexneri 7b strain 94-3007 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

75. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR213456 (Shigella flexneri strain AUSMDU00008332 isolate AUSMDU00008332 plasmid 2) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

76. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026771 (Shigella flexneri Y strain 93-3063 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

77. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044157 (Shigella flexneri strain AR-0424 plasmid pAR-0424-2, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

78. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026763 (Shigella boydii strain NCTC 9850 plasmid unnamed) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

79. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026876 (Shigella boydii strain ATCC 35964 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

80. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026837 (Shigella boydii strain ATCC 49812 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

81. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026796 (Shigella boydii strain ATCC BAA-1247 plasmid unnamed) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

82. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044154 (Shigella flexneri strain AR-0425 plasmid pAR-0425-2, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

83. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034933 (Shigella flexneri strain 2013C-3749 plasmid p2013C-3749-2, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

84. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP037924 (Shigella flexneri 5a str. M90T plasmid pWR100, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

85. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP037924 (Shigella flexneri 5a str. M90T plasmid pWR100, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

86. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_007608 (Shigella boydii Sb227 plasmid pSB4_227, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

87. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041512 (Shigella boydii strain KCCM 41690 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

88. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027028 (Shigella dysenteriae strain E670/74 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

89. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_019197 (Shigella flexneri plasmid pSF5, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

90. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026830 (Shigella dysenteriae strain ATCC 12039 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
tgtcatttcgaggaaaagggcttggcgcgg	Protospacer
*****  **************** *. ..

91. spacer 1.13|973096|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_013448 (Nocardia aobensis plasmid pYS1, complete sequence) position: , mismatch: 8, identity: 0.733

aacaatgagggcgcggccttctgggagcac	CRISPR spacer
gacaacgagggcgcggcctgctggttcatc	Protospacer
.****.************* ****     *

92. spacer 1.13|973096|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_017791 (Deinococcus gobiensis I-0 plasmid P2, complete sequence) position: , mismatch: 8, identity: 0.733

aacaatgagggcgcggccttctgggagcac	CRISPR spacer
gccggggagggcgcggtcttctgggtgcag	Protospacer
. *.. **********.******** ***

93. spacer 1.14|973162|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_015708 (Pseudoalteromonas sp. SANK 73390 plasmid pTML1 carrying thiomarinol biosynthesis cluster) position: , mismatch: 8, identity: 0.733

aaaatgagtaccgtcgagttctgccaaaat	CRISPR spacer
aaaatgagtgccgtcgagttccgttaccga	Protospacer
*********.***********.*..*  .

94. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 8, identity: 0.733

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
ctcgatgtcgcgcaggcgcgtgtcgccgtc	Protospacer
  **** ********* ******** *

95. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP005085 (Sphingobium sp. TKS plasmid pTK1, complete sequence) position: , mismatch: 8, identity: 0.733

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
ccacatctggcgcaggggcgtggcggctgc	Protospacer
    **** ************* ****.*

96. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to JX403939 (Pseudomonas phage YMC/01/01/P52_PAE_BP, complete genome) position: , mismatch: 8, identity: 0.733

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
gcgagcgtcgcgcaggggcttgtcggccag	Protospacer
*  ... ************ ********.*

97. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_042342 (Pseudomonas virus H66, complete genome) position: , mismatch: 8, identity: 0.733

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
gcgagcgtcgcgcaggggcttgtcggccag	Protospacer
*  ... ************ ********.*

98. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to KU310943 (Pseudomonas phage YMC11/07/P54_PAE_BP, complete genome) position: , mismatch: 8, identity: 0.733

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
gcgagcgtcgcgcaggggcttgtcggccag	Protospacer
*  ... ************ ********.*

99. spacer 1.1|972304|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.7

caactcgccttcgagcgcctggatacggcg	CRISPR spacer
acggaaaccttcgagcgcctggacgcggcg	Protospacer
  .   .****************..*****

100. spacer 1.3|972436|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_022050 (Paracoccus aminophilus JCM 7686 plasmid pAMI8, complete sequence) position: , mismatch: 9, identity: 0.7

tccccgccacaagcacggacacgggcgggg	CRISPR spacer
gccccgccacaagcacggccacaatccaat	Protospacer
 ***************** ***.. * ..

101. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 9, identity: 0.7

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
cttctcgggggcctccccggcggcgaaggg	Protospacer
     ***********.**********.

102. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 9, identity: 0.7

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
cttctcgggggcctccccggcggcgaaggg	Protospacer
     ***********.**********.

103. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 9, identity: 0.7

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
cttctcgggggcctccccggcggcgaaggg	Protospacer
     ***********.**********.

104. spacer 1.7|972700|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NC_011143 (Phenylobacterium zucineum HLK1 plasmid, complete sequence) position: , mismatch: 9, identity: 0.7

aaggacgggggcctcctcggcggcgaaatc	CRISPR spacer
gttcgcgagggccttctcggcggcgaaaat	Protospacer
.   .**.******.************* .

105. spacer 1.9|972832|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP041074 (Bacillus tropicus strain LM1212-W3 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.7

ggttccaccatcgccaataggctggccctt	CRISPR spacer
tgatccaccaccgccaataggctgaaataa	Protospacer
 * *******.*************.  .

106. spacer 1.9|972832|30|NZ_CP015736|CRISPRCasFinder,CRT matches to NZ_CP024774 (Bacillus thuringiensis LM1212 plasmid pLM3, complete sequence) position: , mismatch: 9, identity: 0.7

ggttccaccatcgccaataggctggccctt	CRISPR spacer
tgatccaccaccgccaataggctgaaataa	Protospacer
 * *******.*************.  .

107. spacer 1.13|973096|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_017771 (Deinococcus gobiensis I-0 plasmid P3, complete sequence) position: , mismatch: 9, identity: 0.7

aacaatgagggcgcggccttctgggagcac	CRISPR spacer
cacactgagggcgcggccttctaccgtagc	Protospacer
 *** *****************.  .  .*

108. spacer 1.13|973096|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 9, identity: 0.7

aacaatgagggcgcggccttctgggagcac	CRISPR spacer
gttcccgagggcgcggccttctcggagaag	Protospacer
. .  .**************** **** *

109. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 9, identity: 0.7

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
gggcgcgtcgcgcagggccgtgtcggcctt	Protospacer
*.  .. ********** **********

110. spacer 1.10|972898|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010858 (Marinovum algicola DG 898 plasmid pMaD3) position: , mismatch: 10, identity: 0.667

tgtcagatcgaggaaaagggctttgtttac	CRISPR spacer
gccgagatcgaggaacagggctttgccatg	Protospacer
  . *********** *********..

111. spacer 1.15|973228|30|NZ_CP015736|CRISPRCasFinder,CRT,PILER-CR matches to MK524524 (Streptomyces phage Caelum, complete genome) position: , mismatch: 10, identity: 0.667

gacgatctcgcgcaggggcgtgtcggccgg	CRISPR spacer
cgtcatctcgcgcagggacgtgtcgctgat	Protospacer
 .. *************.******* . .

112. spacer 3.5|2032638|40|NZ_CP015736|CRISPRCasFinder matches to NZ_CP003988 (Streptomyces sp. 769 plasmid pSGZL, complete sequence) position: , mismatch: 11, identity: 0.725

tgtcggccgcgtcgacgagatcagccgcaccgtcggcgag	CRISPR spacer
cccggcccctatcgacgagatcatccgcacggtcggcgac	Protospacer
. . * ** ..************ ****** ********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1137611 : 1150713

Paracoccus_phage(25.0%)

portal,protease,tail,capsid,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_064329500.1\|1137611_1138748_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	4.6e-60	37.5
WP_064329501.1\|1139128_1139437_+	hypothetical protein	NA	NA	NA	NA
WP_133033157.1\|1139585_1140143_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	1.8e-25	42.5
WP_064329502.1\|1140215_1141460_+\|capsid	phage major capsid protein	Q3HQT0	Burkholderia_phage	4.7e-82	44.4
WP_064329503.1\|1141609_1142179_+	hypothetical protein	NA	NA	NA	NA
WP_064329504.1\|1142178_1142517_+\|head	phage head closure protein	NA	NA	NA	NA
WP_064329505.1\|1142513_1142921_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_064329506.1\|1142948_1143356_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_084437808.1\|1143288_1143918_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_064329508.1\|1143921_1144455_+\|tail	phage tail tape measure protein	D6PFD6	uncultured_phage	8.9e-06	30.9
WP_064329509.1\|1144764_1145400_+	DUF2460 domain-containing protein	A0A0K1Y6G4	Rhodobacter_phage	2.1e-41	47.2
WP_064329510.1\|1145396_1146287_+	DUF2163 domain-containing protein	A0A0B5A5B8	Paracoccus_phage	1.2e-63	46.6
WP_084438282.1\|1146288_1146864_+	peptidase P60	A0A1V0DYB6	Dinoroseobacter_phage	7.1e-33	50.0
WP_064329512.1\|1146867_1150713_+	hypothetical protein	A0A0K1LL82	Rhodobacter_phage	5.0e-223	39.9

DBSCAN-SWA_2

1415192 : 1425125

Diachasmimorpha_longicaudata_entomopoxvirus(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168168947.1\|1415192_1416944_-	gamma-glutamyltransferase	Q5GF27	Diachasmimorpha_longicaudata_entomopoxvirus	5.9e-06	23.5
WP_064329746.1\|1417221_1417854_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	5.5e-63	60.7
WP_064329747.1\|1418142_1419420_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.6e-133	58.4
WP_064329748.1\|1419834_1422258_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	9.8e-193	46.8
WP_023516583.1\|1422463_1422739_+	HU family DNA-binding protein	A0A172Q061	Acinetobacter_phage	1.0e-05	35.2
WP_064329749.1\|1422929_1425125_+	esterase-like activity of phytase family protein	E3SJA5	Synechococcus_phage	4.4e-83	41.6

DBSCAN-SWA_3

1626191 : 1694778

uncultured_Mediterranean_phage(43.48%)

transposase,tRNA,integrase

attL 1617583:1617601|attR 1705457:1705475

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1617583:1617601	attL	NA	NA	NA	NA
WP_064332486.1\|1626191_1627952_+\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_064329915.1\|1628015_1631339_+	hypothetical protein	NA	NA	NA	NA
WP_064329916.1\|1631465_1632485_+	beta-N-acetylhexosaminidase	A0A1B1IVS3	uncultured_Mediterranean_phage	1.2e-22	41.9
WP_064329917.1\|1632597_1633407_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.6e-33	34.9
WP_084437839.1\|1633381_1634113_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.4e-38	43.9
WP_064329918.1\|1634275_1635379_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	4.3e-10	32.3
WP_023511864.1\|1635421_1635619_+	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	1.6e-08	72.1
WP_064329919.1\|1635669_1636299_+	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_064329920.1\|1636295_1637132_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	4.5e-44	41.9
WP_064329921.1\|1637201_1638485_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.8e-100	46.7
WP_064329922.1\|1638504_1639275_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.0e-26	29.8
WP_064329923.1\|1639271_1639928_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	5.3e-16	36.6
WP_064329924.1\|1640188_1640818_+	hypothetical protein	NA	NA	NA	NA
WP_064329925.1\|1640969_1642550_+	peptidoglycan DD-metalloendopeptidase family protein	I3PV24	Clostridium_phage	4.8e-15	33.3
WP_064329926.1\|1642878_1643748_-	ATP-binding protein	NA	NA	NA	NA
WP_064329927.1\|1643931_1644264_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	9.8e-11	36.5
WP_064332488.1\|1644352_1646860_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	4.9e-38	38.8
WP_064329928.1\|1646852_1647239_+	hypothetical protein	NA	NA	NA	NA
WP_064332489.1\|1647303_1648116_+	phytoene/squalene synthase family protein	NA	NA	NA	NA
WP_064329929.1\|1648230_1648683_+	hypothetical protein	NA	NA	NA	NA
WP_064329930.1\|1648891_1650301_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_023511883.1\|1650444_1650588_-	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_064496054.1\|1650931_1651075_-	DUF1127 domain-containing protein	A0A0F6YPC3	Sinorhizobium_phage	6.2e-07	54.5
WP_064329931.1\|1652179_1653283_+	DUF2157 domain-containing protein	NA	NA	NA	NA
WP_064329932.1\|1653285_1653876_+	GDYXXLXY domain-containing protein	NA	NA	NA	NA
WP_064329933.1\|1654366_1655845_+	trigger factor	NA	NA	NA	NA
WP_064329934.1\|1656554_1658090_-	HAMP domain-containing histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	2.2e-20	31.6
WP_064329935.1\|1658362_1658926_+	thermonuclease family protein	NA	NA	NA	NA
WP_084438292.1\|1658970_1659612_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_064329937.1\|1659678_1660167_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_064329938.1\|1660194_1660569_-	hypothetical protein	NA	NA	NA	NA
WP_064329939.1\|1660570_1661443_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_064329940.1\|1661608_1662412_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_064329941.1\|1662505_1663912_-	Si-specific NAD(P)(+) transhydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.1e-39	26.4
WP_064329942.1\|1664474_1666157_-	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_064329943.1\|1666464_1667676_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	8.0e-95	50.1
WP_064329944.1\|1667676_1670160_-	hypothetical protein	NA	NA	NA	NA
WP_084437849.1\|1670569_1671202_-	hypothetical protein	NA	NA	NA	NA
WP_084438294.1\|1671396_1672143_+	recombinase family protein	Q6DMS6	Streptococcus_phage	8.1e-05	25.0
WP_145925838.1\|1672210_1673429_+\|transposase	IS3 family transposase	A0A1B0Z042	Pseudomonas_phage	2.2e-76	53.9
WP_145926002.1\|1674243_1675116_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_064329947.1\|1675108_1676044_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_064329948.1\|1676367_1677159_+	hypothetical protein	NA	NA	NA	NA
WP_064329949.1\|1677145_1678063_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_064329950.1\|1678221_1679154_+	restriction endonuclease	A0A1S6KZY3	Salmonella_phage	3.7e-07	45.7
WP_064329951.1\|1679193_1680120_+	HNH endonuclease	NA	NA	NA	NA
WP_060583174.1\|1682009_1683509_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_003501246.1\|1683510_1684245_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.5e-32	31.2
WP_168168897.1\|1685622_1685991_+\|transposase	transposase	NA	NA	NA	NA
WP_064329397.1\|1685987_1686341_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_064329396.1\|1686403_1688056_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.1e-82	40.0
WP_064329955.1\|1689237_1690197_-	hypothetical protein	NA	NA	NA	NA
WP_064329956.1\|1690193_1691459_-	three-Cys-motif partner protein TcmP	NA	NA	NA	NA
WP_064329957.1\|1691483_1692266_-	DUF5131 family protein	A0A2P1A0W3	Gordonia_phage	1.1e-49	45.9
WP_084437855.1\|1692317_1692695_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_064329958.1\|1692699_1693065_-	hypothetical protein	NA	NA	NA	NA
WP_064329959.1\|1693108_1693528_-	hypothetical protein	NA	NA	NA	NA
WP_064329960.1\|1693524_1694778_-\|integrase	site-specific integrase	A0A248SL35	Klebsiella_phage	5.5e-163	67.8
1705457:1705475	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1816708 : 1827330

uncultured_Mediterranean_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_064330053.1\|1816708_1819627_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	61.4
WP_064330054.1\|1819919_1820426_+	single-stranded DNA-binding protein	R9TP78	Rhizobium_phage	6.2e-49	61.8
WP_064330055.1\|1820503_1820911_+	cupin domain-containing protein	NA	NA	NA	NA
WP_064330056.1\|1821223_1821853_-	MarC family protein	NA	NA	NA	NA
WP_064330057.1\|1822095_1824876_+	DNA gyrase subunit A	A0A1B1IVS2	uncultured_Mediterranean_phage	1.9e-75	42.2
WP_162853123.1\|1825099_1825246_-	hypothetical protein	NA	NA	NA	NA
WP_064330058.1\|1825634_1826129_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	9.4e-26	38.2
WP_064330059.1\|1826162_1826732_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	8.3e-42	58.0
WP_064330060.1\|1826814_1827330_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	4.2e-45	57.5

DBSCAN-SWA_5

2396951 : 2419665

Ochrobactrum_phage(45.0%)

tail,integrase,transposase

attL 2400593:2400611|attR 2418218:2418236

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_064332558.1\|2396951_2398439_-\|tail	phage tail protein	A0A2I7S9H0	Vibrio_phage	2.8e-49	27.7
WP_064330526.1\|2398441_2398627_-	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_064330528.1\|2399237_2399672_-	DUF1320 domain-containing protein	B7SDP4	Haemophilus_phage	4.4e-11	36.0
WP_064330529.1\|2399848_2400271_-	hypothetical protein	NA	NA	NA	NA
WP_064330530.1\|2400383_2401277_-	hypothetical protein	J9SVY7	Pseudomonas_phage	2.0e-74	45.3
2400593:2400611	attL	NA	NA	NA	NA
WP_064330531.1\|2401288_2401678_-	hypothetical protein	NA	NA	NA	NA
WP_064332559.1\|2401679_2402717_-	hypothetical protein	M4SNT6	Rhodobacter_phage	2.7e-38	36.0
WP_064330532.1\|2402780_2403287_-	phage virion morphogenesis protein	A0A2K9VH22	Faecalibacterium_phage	6.9e-16	35.8
WP_064330533.1\|2403283_2404366_-	hypothetical protein	J9STS2	Pseudomonas_phage	6.8e-53	46.6
WP_064330534.1\|2404484_2406110_-	DUF935 domain-containing protein	M4SPR8	Rhodobacter_phage	7.0e-110	43.6
WP_064330535.1\|2406109_2407765_-	hypothetical protein	A0A219VH72	Ochrobactrum_phage	2.7e-218	73.9
WP_064330536.1\|2407757_2408399_-	DUF3486 family protein	A0A219VH75	Ochrobactrum_phage	6.9e-45	49.0
WP_064330537.1\|2408405_2408717_-	hypothetical protein	NA	NA	NA	NA
WP_064330538.1\|2408727_2409030_-	DUF2730 family protein	A0A219VHD8	Ochrobactrum_phage	5.0e-06	27.1
WP_064330539.1\|2409243_2409609_-	hypothetical protein	A0A068CE23	Rhizobium_phage	6.3e-11	42.6
WP_064330540.1\|2409605_2409863_-	hypothetical protein	A0A219VHD7	Ochrobactrum_phage	4.1e-09	50.7
WP_064332560.1\|2409866_2410598_-	TIGR02594 family protein	R9TRQ2	Rhizobium_phage	4.5e-32	38.2
WP_064330541.1\|2410684_2411071_-	response regulator transcription factor	NA	NA	NA	NA
WP_064330542.1\|2411089_2411299_-	hypothetical protein	NA	NA	NA	NA
WP_064330543.1\|2411295_2411946_-	regulatory protein GemA	NA	NA	NA	NA
WP_084437931.1\|2411942_2412191_-	hypothetical protein	R9U2R5	Rhizobium_phage	3.0e-12	47.1
WP_145925909.1\|2412187_2412469_-	hypothetical protein	NA	NA	NA	NA
WP_064330545.1\|2412468_2412702_-	hypothetical protein	NA	NA	NA	NA
WP_064330546.1\|2412691_2413066_-	hypothetical protein	NA	NA	NA	NA
WP_064330547.1\|2413055_2413322_-	hypothetical protein	NA	NA	NA	NA
WP_064330548.1\|2413333_2413993_-	DUF3164 family protein	A0A1B0T6L8	Pelagibaca_phage	2.6e-55	50.2
WP_064330549.1\|2414005_2414527_-	hypothetical protein	NA	NA	NA	NA
WP_064330550.1\|2414523_2414829_-	hypothetical protein	NA	NA	NA	NA
WP_064330551.1\|2414828_2415851_-	AAA family ATPase	A0A219VHC7	Ochrobactrum_phage	1.2e-62	42.9
WP_145925910.1\|2415936_2417976_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A219VHD4	Ochrobactrum_phage	2.9e-129	51.7
WP_064330552.1\|2417972_2418434_-	hypothetical protein	A0A219VHC5	Ochrobactrum_phage	2.3e-50	66.0
2418218:2418236	attR	NA	NA	NA	NA
WP_064330553.1\|2418430_2419294_-	ParB N-terminal domain-containing protein	A0A219VHB6	Ochrobactrum_phage	2.1e-52	45.9
WP_064330554.1\|2419293_2419665_-	hypothetical protein	A0A219VHC3	Ochrobactrum_phage	2.2e-19	43.3

DBSCAN-SWA_6

2828332 : 2868267

Rhizobium_phage(76.32%)

tail,integrase,transposase,plate,terminase

attL 2818448:2818465|attR 2872281:2872298

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2818448:2818465	attL	NA	NA	NA	NA
WP_084437990.1\|2828332_2829241_+\|integrase	tyrosine-type recombinase/integrase	A0A067XRF8	Caulobacter_phage	2.7e-63	48.7
WP_064332593.1\|2829295_2829772_-	thermonuclease family protein	NA	NA	NA	NA
WP_145925923.1\|2830007_2830232_-	hypothetical protein	R9U2V1	Rhizobium_phage	4.7e-17	63.4
WP_064330888.1\|2830362_2830680_-	hypothetical protein	NA	NA	NA	NA
WP_064330889.1\|2830722_2831010_-	hypothetical protein	NA	NA	NA	NA
WP_064330891.1\|2833652_2834093_-	hypothetical protein	A0A291L9V2	Bordetella_phage	3.5e-24	45.6
WP_084437992.1\|2834098_2835214_-	hypothetical protein	R9U468	Rhizobium_phage	1.8e-40	49.7
WP_084437994.1\|2835206_2836343_-\|plate	phage baseplate assembly protein	R9U1E3	Rhizobium_phage	8.0e-129	66.4
WP_064332595.1\|2836335_2836743_-	hypothetical protein	R9U2U6	Rhizobium_phage	7.2e-56	71.1
WP_064330894.1\|2837340_2838339_-	late control protein D	R9U464	Rhizobium_phage	3.3e-126	69.3
WP_064330895.1\|2838338_2838530_-	hypothetical protein	NA	NA	NA	NA
WP_064330896.1\|2838531_2838801_-	hypothetical protein	R9U1D8	Rhizobium_phage	3.3e-33	73.9
WP_064330897.1\|2838797_2839274_-	hypothetical protein	R9U2U2	Rhizobium_phage	1.2e-49	62.0
WP_064330898.1\|2839270_2841862_-	tape measure protein	R9U4C6	Rhizobium_phage	7.7e-111	50.9
WP_064330899.1\|2842101_2842437_-	hypothetical protein	R9U460	Rhizobium_phage	4.1e-33	66.4
WP_064330900.1\|2842518_2842827_-	hypothetical protein	R9U1D3	Rhizobium_phage	1.8e-06	33.3
WP_064330901.1\|2842867_2843374_-\|tail	phage tail protein	R9U2T4	Rhizobium_phage	5.2e-56	58.4
WP_064330902.1\|2843388_2844657_-\|tail	phage tail protein	R9U4C2	Rhizobium_phage	2.3e-185	76.8
WP_064330903.1\|2844660_2844879_-	hypothetical protein	NA	NA	NA	NA
WP_145925924.1\|2844890_2845400_-	hypothetical protein	R9U453	Rhizobium_phage	3.8e-54	66.5
WP_064330905.1\|2845387_2845855_-	DUF1320 family protein	R9U1C9	Rhizobium_phage	6.5e-61	76.3
WP_064330906.1\|2845937_2846357_-	hypothetical protein	R9U2T2	Rhizobium_phage	8.3e-07	57.6
WP_064330907.1\|2846370_2847324_-	hypothetical protein	R9U4B8	Rhizobium_phage	1.4e-142	78.0
WP_064330908.1\|2847335_2847671_-	DUF2190 family protein	R9U0T4	Rhizobium_phage	1.0e-28	64.9
WP_064330909.1\|2847685_2848807_-	hypothetical protein	R9U448	Rhizobium_phage	8.4e-131	65.1
WP_064330910.1\|2849082_2849547_-	phage virion morphogenesis protein	R9U1C4	Rhizobium_phage	5.0e-45	63.2
WP_084437998.1\|2849649_2852508_-	DUF935 family protein	R9U2S4	Rhizobium_phage	4.1e-230	79.6
WP_064330911.1\|2852582_2854238_-\|terminase	phage terminase large subunit	R9U0T3	Rhizobium_phage	3.0e-270	82.1
WP_064330912.1\|2854234_2854738_-	DUF1804 family protein	R9U444	Rhizobium_phage	2.2e-75	89.2
WP_064330913.1\|2854727_2854973_-	hypothetical protein	NA	NA	NA	NA
WP_168168909.1\|2854969_2855134_-	hypothetical protein	NA	NA	NA	NA
WP_064330914.1\|2855171_2855519_-	hypothetical protein	NA	NA	NA	NA
WP_168168952.1\|2855515_2856004_-	hypothetical protein	F8TUT3	EBPR_podovirus	1.3e-11	36.0
WP_064330916.1\|2856646_2857021_-	hypothetical protein	F8TVB5	EBPR_siphovirus	6.4e-27	51.7
WP_064330917.1\|2857017_2857464_-	regulatory protein GemA	R9U1B6	Rhizobium_phage	6.5e-50	68.3
WP_145925926.1\|2857460_2857745_-	hypothetical protein	NA	NA	NA	NA
WP_145925927.1\|2857737_2857995_-	hypothetical protein	NA	NA	NA	NA
WP_064330919.1\|2857991_2858447_-	hypothetical protein	R9U4A4	Rhizobium_phage	2.6e-46	64.2
WP_064330920.1\|2858443_2858917_-	hypothetical protein	NA	NA	NA	NA
WP_145925928.1\|2858913_2859414_-	hypothetical protein	NA	NA	NA	NA
WP_084438000.1\|2859370_2860120_-	DUF3164 family protein	A0A1B0T6L8	Pelagibaca_phage	1.7e-39	38.4
WP_064330922.1\|2860140_2860389_-	hypothetical protein	NA	NA	NA	NA
WP_064330923.1\|2860385_2860604_-	hypothetical protein	R9U2R2	Rhizobium_phage	2.4e-10	58.5
WP_064330924.1\|2860593_2860986_-	hypothetical protein	G8GWC3	Rhodobacter_phage	5.9e-31	55.3
WP_145925929.1\|2860970_2861570_-	hypothetical protein	G8GWC2	Rhodobacter_phage	2.2e-37	44.0
WP_064330925.1\|2861566_2862334_-	ATP-binding protein	G8GWC1	Rhodobacter_phage	5.1e-95	66.9
WP_064330926.1\|2862360_2864631_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	R9U1A8	Rhizobium_phage	0.0e+00	72.3
WP_064330927.1\|2864627_2865095_-	hypothetical protein	R9U2Q7	Rhizobium_phage	5.3e-63	78.7
WP_064330928.1\|2865097_2866081_-	ParB N-terminal domain-containing protein	R9U496	Rhizobium_phage	3.4e-112	66.1
WP_064330929.1\|2866206_2866833_-	hypothetical protein	R9U0S2	Rhizobium_phage	1.9e-15	33.7
WP_168168910.1\|2866829_2866982_-	hypothetical protein	NA	NA	NA	NA
WP_064330930.1\|2866978_2867287_-	hypothetical protein	NA	NA	NA	NA
WP_064330931.1\|2867283_2867586_-	hypothetical protein	NA	NA	NA	NA
WP_145925930.1\|2867739_2868267_+	helix-turn-helix domain-containing protein	G8GWB1	Rhodobacter_phage	1.1e-11	31.3
2872281:2872298	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage