CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP011515	Mitsuaria sp. 7 plasmid, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP011514	Mitsuaria sp. 7, complete genome	1 crisprs	WYL,DinG,csa3,DEDDh,Cas9_archaeal,RT	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

60810 : 68242

Enterobacteria_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_067283649.1\|60810_61362_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	5.9e-45	50.5
WP_067283651.1\|61361_62252_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	1.2e-100	61.5
WP_157523195.1\|62266_63226_-	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	2.7e-29	37.5
WP_067283655.1\|63162_64221_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	7.5e-89	49.2
WP_067283656.1\|64306_65587_-	nucleotide sugar dehydrogenase	NA	NA	NA	NA
WP_067283984.1\|65685_67095_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	8.0e-46	27.7
WP_067283658.1\|67219_68242_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	6.6e-74	42.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP011514

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011514_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011514_1

858751-858831

Orphan

Consensus_repeat	Method
CCCTCTCCCGCGTTGCGGGAGAGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011514_1

>merge|NZ_CP011514|1|858751-858831|CRISPRCasFinder
CCCTCTCCCGCGTTGCGGGAGAGGGAGCCACGGAGCTCGGTGGCGGTTCCTCGAACTCCCTCTCCCGCTTGCGGGAGAGGG

>NZ_CP011514|1|1|858751-858831|CRISPRCasFinder
CCCTCTCCCGCGTTGCGGGAGAGGG	AGCCACGGAGCTCGGTGGCGGTTCCTCGAAC
TCCCTCTCCCGCTTGCGGGAGAGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011514.1\|WP_067270126.1\|850296_854016_-\|response-regulator	unknown	unknown	gnl\|CDD\|236848
NZ_CP011514.1\|WP_067270125.1\|845690_849077_-\|response-regulator	unknown	unknown	gnl\|CDD\|236848
NZ_CP011514.1\|WP_067270132.1\|856410_858069_+\|ATP-dependent-DNA-ligase	unknown	unknown	gnl\|CDD\|236428
NZ_CP011514.1\|WP_157521910.1\|870011_871049_-\|peptidase-S11	unknown	unknown	gnl\|CDD\|236952
NZ_CP011514.1\|WP_067270136.1\|861700_861937_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011514.1\|WP_067270128.1\|854138_855089_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011514.1\|WP_082938292.1\|849076_850300_-\|two-component-system-response-regulator	unknown	unknown	gnl\|CDD\|225971
NZ_CP011514.1\|WP_082938293.1\|855253_856414_+\|ligase-associated-DNA-damage-response-exonuclease	unknown	unknown	gnl\|CDD\|274995
NZ_CP011514.1\|WP_067270123.1\|841303_841780_-\|response-regulator	unknown	unknown	gnl\|CDD\|381147
NZ_CP011514.1\|WP_157522977.1\|861027_861675_+\|ligase-associated-DNA-damage-response-endonuclease-PdeM	unknown	unknown	gnl\|CDD\|274996
NZ_CP011514.1\|WP_067270144.1\|871210_871738_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011514.1\|WP_082938295.1\|867238_869158_-\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|226646
NZ_CP011514.1\|WP_082938294.1\|866627_867242_-\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|376760
NZ_CP011514.1\|WP_067270124.1\|841827_845694_-\|response-regulator	unknown	unknown	gnl\|CDD\|236848
NZ_CP011514.1\|WP_067270146.1\|871734_872229_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011514.1\|WP_067270122.1\|840163_841273_-\|trypsin-like-serine-protease	unknown	unknown	gnl\|CDD\|273938
NZ_CP011514.1\|WP_067270142.1\|869291_869852_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011514.1\|WP_157521908.1\|862029_864606_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011514.1\|WP_067270121.1\|839005_840022_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NZ_CP011514.1\|WP_067270149.1\|872361_874458_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288

Protein	Function_ID	Function_description	E-value
NZ_CP011514.1\|WP_067270126.1\|850296_854016_-\|response-regulator	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	6.07922e-128
NZ_CP011514.1\|WP_067270125.1\|845690_849077_-\|response-regulator	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	7.9951e-103
NZ_CP011514.1\|WP_067270132.1\|856410_858069_+\|ATP-dependent-DNA-ligase	gnl\|CDD\|236428	PRK09247, PRK09247, ATP-dependent DNA ligase; Validated.	0
NZ_CP011514.1\|WP_157521910.1\|870011_871049_-\|peptidase-S11	gnl\|CDD\|236952	PRK11669, pbpG, D-alanyl-D-alanine endopeptidase; Provisional.	1.40115e-72
NZ_CP011514.1\|WP_082938292.1\|849076_850300_-\|two-component-system-response-regulator	gnl\|CDD\|225971	COG3437, COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms].	5.73169e-142
NZ_CP011514.1\|WP_082938293.1\|855253_856414_+\|ligase-associated-DNA-damage-response-exonuclease	gnl\|CDD\|274995	TIGR04122, hypothetical_protein, putative exonuclease, DNA ligase-associated. Members of this protein family frequently are found annotated as a putative exonuclease involved in mRNA processing. This protein is found, exclusively in bacteria, associated with three other proteins: an ATP-dependent DNA ligase, a helicase, and putative phosphoesterase.	0
NZ_CP011514.1\|WP_067270123.1\|841303_841780_-\|response-regulator	gnl\|CDD\|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.93764e-47
NZ_CP011514.1\|WP_157522977.1\|861027_861675_+\|ligase-associated-DNA-damage-response-endonuclease-PdeM	gnl\|CDD\|274996	TIGR04123, hypothetical_protein, metallophosphoesterase, DNA ligase-associated. Members of this protein family are an uncharacterized putative metallophosphoesterase associated with a DNA ligase, a helicase, and a putative exonuclease. It may play a role in DNA repair. Its system is present in about 12 % of prokaryotic reference genomes.	1.18443e-83
NZ_CP011514.1\|WP_082938295.1\|867238_869158_-\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|226646	COG4178, COG4178, ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only].	0
NZ_CP011514.1\|WP_082938294.1\|866627_867242_-\|MgtC/SapB-family-protein	gnl\|CDD\|376760	pfam02308, MgtC, MgtC family. The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologs is not known.	1.51863e-51
NZ_CP011514.1\|WP_067270124.1\|841827_845694_-\|response-regulator	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	3.78988e-72
NZ_CP011514.1\|WP_067270122.1\|840163_841273_-\|trypsin-like-serine-protease	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	6.93759e-93
NZ_CP011514.1\|WP_067270149.1\|872361_874458_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	9.19085e-153
NZ_CP011514.1\|WP_067270121.1\|839005_840022_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	1.89422e-179

>NZ_CP011514.1|WP_067270132.1|856410_858069_+|ATP-dependent-DNA-ligase
MKAFAALYRDLDASTSNLAKQAALRGYLRQAPPEDAAWAVYFLAGGKPRQLVPTKLLREQARLVAGLPEWLFDESYEAVGDLAETISLLLPEPAEVIERPLSVWMTEHLLPLRGQPPEALAVTLQAQWAALAIEQRFVHLKLITGAFRVGVSKLQVTQALAAVGGLDAKLVAQRLMGYTHIGATPSAADYAALIAPADHEGADGAGRGLQPYPFFLAHPFNLPVEQFDAAIGPASEWLIEWKWDGIRAQLVKRGGEVAIWSRGEELVTERFPELRAMGEALPDGTVLDGEILVWRDGRAMPFAELQKRIGRKTLSAKLLGELPAALCVYDLLEENGEDLRGQPQHERRARLERLVAAHPLAGLELSPLISGADWDDLARQREQARSLGVEGMMLKRRDARYGVGRTKDVGVWWKWKIDPLSIDAVLIYAQRGHGRRASLYTDYTFAVWNGPADDPARQLVPFAKAYSGLTDAEIRSVDAVIRKTTTETFGPVRSVTPTMVFELGFEGIARSGRHKSGIAVRFPRMLRRREDKPVEEADTLQSLQALLPEEGA
>NZ_CP011514.1|WP_082938293.1|855253_856414_+|ligase-associated-DNA-damage-response-exonuclease
MDSANAPRAGETVQTTGGRADAGAPAAGDLVVARPEGLYCPPGDFYIDPWRPVDRAVITHGHSDHARVGHAHYLAQHDSAAILRRRLGDDITLQTLAYGEAIVHHGVRLSLHPAGHVLGSAQVRLEHGGRVWVASGDYKLEADGTNAPFEPVRCDTFITESTFGLPIYRWPSQPALFAEINDWWRRNAEAGRASVLYAYALGKAQRLLHGVDASIGPIVAHGAVEPLNAVYRAAGVRLPPTFNAGDPALDKAALSRALVIAPPSAASSPWLKRFGPDLADAFASGWMQLRGTRRRRGVDRGFVVSDHADWPGLMAAIRGTGAERVFVTHGSVATMVRWLGEQGLRAQGFATEYGDEEAAGDTAAGDTAPGDAAGGDAPASPSEPAQ
>NZ_CP011514.1|WP_067270128.1|854138_855089_-|hypothetical-protein
MIDYPSARFESGFESTPEGPPPLHPLLAALKANAPSSVRDELALLLRQAREGRLSPAGLLHVLLSQDAYGGSAWQEICAQTGTVALRQLLDGISDLIAAGRLDPAEALALFRASDDAQSPALHVLAAKTDWRGLGEYAEALVALHDKGVLPDTDFASVLLQAWNGETLVQRALLGSTATLAASLELLSLAVRRGTITEADFLKALGAPGFGGYDARGRTVSTAGGPSPLKATFMTASVPVIEVVLRKVESLREIGAMRSERLREVMEPLFQSTGSAIRRPSAVLADDVAQAKALVARARERWFAAGPDTKDTATAR
>NZ_CP011514.1|WP_067270126.1|850296_854016_-|response-regulator
MGRVSDWLLAHRPLAWALAAGAALALGIAASELHRRSLEHDFQRSLNNAAQREALALQGLTLTGQGMGAIVLAGQLNPSLKTTATLTDFEETRRTRPAADTLEVIATSVGAQQVFVVNARGRIIAAWDDEGSSPIGLDVAFRQYFRQAMRGQPNVFAGISLSTGQRVYWLAAPVYRRPGKDSEIVGAVVARVYVDGLDHFLDTRSYAGALLISPSGVVLASSRRDWRMILHGPATPQRAQAITAARQFGKLFEDAARSRSLPFTLDGPDVEIGGVRHAVAHADVSWNDPTGPWRLVLLGDLDALEPSATRVGITALVALLAFGLLAASLRSLAHSASRDRKDLELQAQHRQLQSLLAERERAQETLQRAKEDAEGATRAKSDFLANMSHEIRTPMNAIIGMSHLALQTGLDARQRNYIEKVHRSAENLLGVIDDILDFSRIEAGKLSLECVPFRMEDVLDHLVNLIGFRVEDKGLELLLNVPPDLPTALIGDPLRLGQVLVNLGNNAAKFTDHGEIIVGIEAVTLAPEQTAAAVGPSAGADLAALDVVAACAPEVELHFQVRDTGIGMTPDQQARLFRSFSQADSSTTRKYGGSGLGLAICKQLVEMMGGRIWLESTPGEGSTFHFTARFVLQAEGSDLPARRALMAHELAHLRTLVVDDNRAAREILSTLGAGFGLEVSTAADGAEAVRDAERAQADGRPYALVLMDWQMPVLDGIEATRQLVDGRLRVPPAVVLVTSFGRDDSLTAALAAAGQSSGQARRPVLLTKPVTASSMLGAIGEALGHADLPAPAAQRRRDSAREAMRLVAGARLLVAEDNELNQELVTALLEDAGVHVTLACNGRVALDLLEASPEGFDGVLMDCQMPVLDGYAATRALRAQPRWADLPVIAMTANAMSGDRERVLEAGMNDHLAKPLNVDLLFETLARWVHPAMPAAEVPMDTRSGAGRRVDTQHGRSEVLEPGGTGTDGADGVGSAGNAGGTGPAARPDSLPQIAGLDVQAGLATAAGHLPLYRKLLRTFHDTQTGFAADFAEAATAGDATTMTRLAHSLRGAAGTLGARPLAAAAGALEEACSQRASAAEREPLLIRAQSLLATLLVSLGRHLAREAMTQATSAASSASAPSSPSWSPTALSPTASATASATVSATPPPVVAAPTLDDGSREHLDALLARLTALLRDSDSSATDAAQELTALLDRLPLPTARARLLRRAADSAARFDFDGALDWLNDDERAASSGRPA
>NZ_CP011514.1|WP_082938292.1|849076_850300_-|two-component-system-response-regulator
MNDLTSAAGAADRRDAADPSDGATVLVVDDTPDNLLLMSELLRDRYRVKIANHGEKALAIAGAEPRPDLILLDVMMPGMDGHEVCRRLKADPATRDVPVIFLTARSDVADETRGLSLGAVDYITKPISPPIVMARVRTHLQLKASADFLRDKAAYLEAEVARRSEELAAIQDVTILAMASLAETRDSDTGNHIRRTQHYVRALAEALQDHPRCRELRAPGFIATLFKSAPLHDIGKIGIPDRILLKPGRFTPDEFEVMKSHPALGRDAIQQAESQLGTPVAFLSTAKDIAYCHQEKWDGSGYPQGLRGEAIPLSARLMALADVYDALISRRVYKDGMTHEEAAAIIAEGSGTHFDPDVVEAFLRIQPEFQSIARRFADDDASLARKRAWMETVSPPDLTPIGVDRGH
>NZ_CP011514.1|WP_067270125.1|845690_849077_-|response-regulator
MRLPGDRSRWVWPDRSAIAWGAALVVSIAAGWGLSAAQRWYLENQLHRALQTTTEREGLSLVQITLSGKDMGAVELIGLVDPLVKTMTRETDADRARLLRPGEAPLRTLAEVLESAGVIVLNGNGMVVGEWGPDQTESFIGRDLSSRSYVQQALKGRSSIYTGLSPDRKIRTLLYAAPVFENHATGSLTVTGAVVARKLSSVLDDFFKSRAHAGGMLISPQGVVFAASRPDWELALVGPVTAERAEALTAMRRFADLFRDPARARVVPFDPVDGAVVEVDGRRLAVAETTVEWNDPAGPWRLVLLDDLSAAWSAQQRLAAAALIAALLLGGYALTRQIAVHRRERELQAAAMVTRADAVRTMFRMAPVGVCLIVNGRIEFLNPLLAEQLGIAQFQDWPRPYADDASRELIDAVLRERRRMRDVEVGLIGAGGETRAYVLSSMPFDYEGDKPGVVLWLVDITRRQEAAREARRAMEAAKDAARAKSSFLAGMGHEIRSPMNVIVGMSDLALQTGLDARQRNYLEKVNGAALSLLDLIDDILDFNSIESGRIALERVPFQLDAVLDRLVDLIGLRAEDKGVELLIHRPADVPDALIGDPMRLGQVLINLGANAVKFTDSGEVIVAVERVPAGDGSGDGAGDGAEDEVELRFSVADSGIGMTQETISRLFHSFNQADTSTTRQYGGSGLGLAVSRQLVEMMGGRIQVTSRPGEGSTFSFTVRLGLRQGSRATATRVSAVMADLSQLRVLVADDNRAARDILGALCAGFGMRVDTAVNGANAAQCVLEAEAGKRPYDLVLMDWQMPVLDGLEATRLIADGRLASPPAILLVTAFGRDATLAAAVAEADPRHRPARLLSKPVTASTLLSAIGEATGRASLPTFAPQRGGATRAAMARLTGTRLLVVEDDPVSGELSAELLRAAGLDVTLAPDGQTALELMARPDPGIDAVLMDCQMPKMDGYETTRRLRQDPRWRELPVIALTASASLEVRERILAAGMNGCLSKPLNVDRLFEALTRLRRGPTTDPAAGDAGAPQTAGLAGVAVGADATSTVAPDAELEALLSRLAERLRHSDATAVEIGGALAAALDRRPPPPARAQLLRRVAAAASGFRFDEALALLSWDAGAPAGGSST
>NZ_CP011514.1|WP_067270124.1|841827_845694_-|response-regulator
MRPLATLLSRHALAAWLIAAALSLLVGALVADQARRVLEDRLRARLATTIDREVLLFRGLTEESKAMGALRLAGRLDPDVKAAALQTELQAALRLRPAADTLSSINDQLGADVTFVVNRNGMIVGEWNRGLQRSPMGEDASHRAYFRESLAGRSAISMALSQATSRRSIYLSAPVFRDSDIRSPVIGVVVTQFYAPSLDRFLTERADMDTLILSPEGVVMASTRPDWALTIAGSVSEERRRQLTAGRRYGRHFDEPRNARPLPFSPEAGDARVEGHRHAVAVRDLGWRDAAGPWRMVLVSDLSTALSVPAQAGLGLLSALMCFAALAALLRSLLLSAARQTQEIALLRQRERFMTIIEHTPAGIGLITDGVVSIANPALRRLVDVEIGQPWPDVYADEDSRARAQSLLESAAGGGGGDVDVELRIVDPHGVRRICQAAFLPVDFGRSGMLVLLTDLTDRLSAENEIRVARESAEATTRAKGDFFANMSHELRTPMNAIIGMSELALQTDLDARQRNYVDKTCRAAETLLGVIDDILDFSRIEAGRLALEHIPFELDEVLAHLVQVVGVGLEEKGVELLLSVPAGLPATLVGDPFRLGQVLAHIGKHAARRSEQDEVVVAVTVVTDGENKEGKVDKENAKESARPPGEDGIVLRFSVRDSGPSLSPAELTRLGRRPAEIDADTPDRGDLALAVCRMLVEMMGGTLRVDSMPGAGLMLHFTARLGIAPPEDHDEEEEAPAALRGRVLVVDDNRVAREVLVALCQGLGLHVDQALDGAGALRAVQAAAREHRPFDWVLMDWRMPGLDGVAAAARLIEEADPVPRIVMVTAFGNDDGLYEAMAELPTEQPLPVLAKPVTDATLRDALGASGASAASGASADAHARRAATQAAMAGLAGARLLVVEDNQVNQELAEELLTNAGIAVTIAGNGAIALERLQQSPDGFDGVLMDCQMPVMDGYDATRQLRQDPRWRELPVIALTANVTGADRARILATGMNDHIAKPLNVDMLFEVLARWVHPVEGATVPAPPQHAHALAHGLPHGSPPSMPSTPSTPSTAATRSARPRPASAPALPVVDGLEARSGMASAANNAGLYLRLLRIFLHSQQETGERLDQAAASDDPRALEHIAHSLRGSSATIGALPLSEAAAALESACRAQAPAARRRELAQAVHVALSRLLHALGETLADDSPPTMPGALYDLSQPPGIPKLEERLTRLRRQLGEHDAAAVDTAERLLAEIDRGRHGLDEPRAAALREALAAATRFDFETARRGLAHDDGAGEALWPRTPHASE
>NZ_CP011514.1|WP_067270123.1|841303_841780_-|response-regulator
MSPTNGDQRPTILIVDDSPEVLSQLYELLKERHRVKVATTGDRALRIAAESPRPDLILLDVLMPGMDGYELCRWLKADAITRDIPVLFLTARSDPADESHGLSLGAVDYITKPISPPILLARVRTHLQLKATADVLRERAAHLEAEIARWAGGDAELS
>NZ_CP011514.1|WP_067270122.1|840163_841273_-|trypsin-like-serine-protease
MSFRSCQVLRRLHSAASIGVLVGVLLPLLVGSGLVQAQPRPVTPRGPLDAQEQNNIAVFRKVSPSVAHITTLAQQRDLFSRHVTEVPSGTGSGFLWDELGHIVTNFHVIRGASAAKVTLSDQSAYDATLVGVDPDRDLAVLRIVAPREKLTPVPMGSSRDLLVGQTVYAIGNPFGLDQTLTRGIVSALNREIESMTQRTIRGAIQTDAAINPGNSGGPLLDSAGRLIGVNTSIFSPSGGSNGIGFAIPADEVNRVVPQLIKHGRVTRPALGLTAGSEQLRQVLRLPKGVVLIGLQPGGGAQRAGLQPFMRGRDGRIVGGDVITAVNGKPVADLDDLLGELEERQVGEKVTLTVWNGGKTRQVQAPLTSD
>NZ_CP011514.1|WP_067270121.1|839005_840022_-|LLM-class-flavin-dependent-oxidoreductase
MQARLSILDLAFIVEGGSAAQALHESMALAQHAERLGYTRYWVAEHHNMDGVASSATAVLIGQIAAATSTIRVGSGGIMLPNHAPLTIAEQFGTLATLFPGRIDLGLGRAPGTDGPTMRALRRHLATAHEDRFPEDVLELIGYLAPAQEGQVVRAVPGQGTEVPVWLLGSSLYGAQLAAYLGLPFAFASHFAPAMLMQALEMYRAQYRPSARHPTPYAAVGLNVVVADTDAQAQRLFTSIQQRFLGMQRGQRGLLPRPIDSMDVLWTAGEKLGVERMLSESIVGSPRTVREGLLATQERTGADEFIVACAVHDPAARRRSYELLAGIAADSAAGSAAR
>NZ_CP011514.1|WP_157522977.1|861027_861675_+|ligase-associated-DNA-damage-response-endonuclease-PdeM
MTLAGERVWLLPGRALWWPATRTVFVADVHLGKAASFRALGQPVPSGTTRDNLDRLSALIDDLRPARLVVLGDFLHAAAAQQPQVLDPVHRWRERHADLAGLLVRGNHDSRAGDPPPSLRFEIVDEPHAMGPFAACHHPRRVPDAYVLAGHLHPATTLHGRAHERHRLPCFCESEGLMILPAFGAFTGTTQAGLPEGSRCHAVGGGSVWPAPGSE
>NZ_CP011514.1|WP_067270136.1|861700_861937_-|hypothetical-protein
MDLDTVSYIFQSPEGTFSIKPRLSRRWRVKHDSMPWGDSFASAEEAAKALSARFAVPADLKEWTEIGDFHTDVGGFNL
>NZ_CP011514.1|WP_157521908.1|862029_864606_-|hypothetical-protein
MRAWSAPPARKNRQGCVIEAPGGKRRAAGASVDSLCAPHTPCRNRWSRWHDATVCCANPALAGSTQARRAARTPMHPLNTATQPLVVVIDDETTILSPREHAPSPIAEATPLARQLARIRLDLLAAMAADHIAHCPRIRSFPDEEASARAFEASCLDYLVSSANARLASPPTDAPKEPASWGWSTEHDLRLKRFLRRAAPQLTEAALCRALARQLLSRIGAPGPDEGPADASLLNIRMAGLKHTLGFRVPEHCVLARDAATGAVHVHGDAFQLGRALWREARSTRGAPEPDVVTADLPGEPSRQLRVEGGEWVSTTGPGRTETTVSLADLARADQAGGLCHRLSDDARERIALTVIEASEIDELMDFPASRISSPAMAAALLARLDDDAMTRWMARQALTERPDIALRVATSCVHAWRHGLVAGNVSQLGKQVVLESLTSVPRNWLDDRSLAWACGLGDEDRVRAVVVGVLGGIGKGLTADEALSILWRAEDHFPLAADSRSRCTDAFLDAIAPALRDGRLSPDQVTRLLGGGTAGEEGYGLTLVFRNGFCDAAGQFLDRLRALQGPQGLSADQLGRILTGAAAGRPSRSTPFSQRTAKLASPTALTRWYAEVLDLWRQGRIDGEHATQLMLGLDTQGWSAWNLALRRQSSEPDPTALLALVDAWVLAIQENLLPRTSLRDGLLSRSPITRQSELARAASNADIDPLSALFRRLGELKRLGVLPDADLVEMLDATVDVDGLTRAVAAEYSRLDAEGQAARRRVAAQRQLTSFERLLNECLVAERLDGASAARLLMARPDGRDSRSVRAAAMAGGHSDSHLRLLDDAVRRGDLSDAQRADAVRAAGGVVLADPPVAIAA
>NZ_CP011514.1|WP_082938294.1|866627_867242_-|MgtC/SapB-family-protein
MSTWTDEVVETVRSEFSDVPDVAQITRIAVRLLLAALLGGILGYEREHHGKAAGIRTHMLVSLGAALFVLVPQQGGMALADMSRVLQGVIAGIGFLGAGAILKLKDEEQVHGLTTAASIWMTAAIGIACGLGREATAVFSMLLALLILAVLPLFTRPHPRKDEDRKDADRTADERKAQARKEPDWPEDVSRDRPQEDGGRDRSA
>NZ_CP011514.1|WP_082938295.1|867238_869158_-|ABC-transporter-ATP-binding-protein/permease
MVHSSSPATDLPPSAPPATPKKAKRRRPPRLSGAAWRQFMQIARPYWLGDQRKAAWGLLLLMIVLMLCETQLAVMLNDKTGEMTSALAERNHSRFWLAVRDSLIVLGFAVPVYAFYYYMRDAFSNHWRRWLTGRFLDGYLDGRKYYEIGAGAAGDIDNPDQRISEDINTFTGRSTHFGLLMIGSMMQLVAFCAVLWSLSKMLVAFLVVYATVGTFLALYVFGSPLIQLNFWQLRREADFRFGLMRLRENAESIAFYRGEPQERAHIESRFESVYQNYWKLIRKQRALNLFQRGFSQLTLVVPAVILAERVLSGDLEVGAAVQAAGAFAAVLTAVSLIVDNFESLSRFVAGIDRLHALSEVMHKRKPRDERAREKIATKHADQLALRALTLYTPQFDRLLVEKLDVALQPGESLLITGVSGCGKSSLLRAIAGLWRCGEGTIEHPPLEDVFFLPQRPYLQPGTLRSQMIYPDTSTELDDDALRAILDEVCLPELAERVGGLDASQDWEKLLSMGEQQRLAFARVLVRTPKMVILDEATSALDGCNERRLYERLCRDGVTLVSIAHRHAVLQHHTHVLRLTGGGAWQLHPAEGYDFDAVEAEAEAAREAALESALEAKLANGADTGPVAKPSEETSTKAST
>NZ_CP011514.1|WP_067270142.1|869291_869852_-|hypothetical-protein
MHPQAPQITNVTQIPNAQPDLHHVMYRLDLLSAETHKLRQEMHEGFALIRKDQEDFKKNQEIFKKELADQRLESAKEFASCRAEFKADLNASRKEFRADLSKARADFKDELQKMREKSREDFDAMLARTKIDVKELMASVVATVDDRIKMSGQASDLRLLKWCARAALSSSAAAGSLAYAVSKLMP
>NZ_CP011514.1|WP_157521910.1|870011_871049_-|peptidase-S11
MTIRDTVLRTLAHTNWKLALPALILTCGSLIVQAASDDPEVVVPTTAPTTAAISPNGVLTPAPAASAGTPEPAPTASSPLIAKSPGTVVAPSPSDEPLMKLPVNARHMLVVDDTGRVLMSKEPDTVVPIASLTKLMTAMVVLDAKQDMNEDIKIDDADVDRLKHSKSRVRVGATMSREAALELALISSENRAASALARHFPGGLPAYEAAVVAKIRALGLSHTSLADPTGLSPNNTSTAAEVARIAAAASKYAVIARISSDKSSEVEVNGRPRELRNTNHLVGAKGWDIRLSKTGYTEEAGRCLAMRMKSGGQTITVILLDADGSAQRLRDAAAIRKSLAKIAAA
>NZ_CP011514.1|WP_067270144.1|871210_871738_-|hypothetical-protein
MIHYADNKTQAFVATLQSLTEASAIEWRIVEPPSPPPGIQPSQPWHFMAVHKGIQLALYRERPISPPTPRFGSTDNFLHVLAIQDSRGREIWQAQHVSYAVERLFDLVHDKVIKIDVILSDVIDPATLASFERDRKLRIQDLIDGDGLLGWFRRQRRALKERFAWTDAGSRTLSS
>NZ_CP011514.1|WP_067270146.1|871734_872229_-|hypothetical-protein
MQSPALATAVAALLAACPPSLIPQWIQDLNTLVGLIGFAITIVVWWQVRSVRLSFQAKARLPGLADEICASRKELDKASKAAGTTRQDLHQMFGGIATLLATAGELMPSRSRAPVNEAILAVKAARVQLDSTPRCHALDLGKTLGALKAAETGVFQTSLALDWK
>NZ_CP011514.1|WP_067270149.1|872361_874458_-|ATP-dependent-helicase
MIAAMCPAALADTQNDVFADLNPEQRSAVEHGLGETSQDGHRPLLVIAGAGSGKTKTLASRVARLIQSGADPQRLLLLTFSRRAAGEMERRAGRVLHRALGLASTQAPPRFPWAGTFHSVGARLLREYAHRIGLAPNFTILDRADAEDLMGLQRQALGLAETTDRFPMKGTCLNIYSRVVNSEARLDQVLQEHFPWCFAVHDELKRLFKAYVEEKQHQQLLDYDDLLLYWSELMSDDTLAAELGERFQHVLVDEYQDTNRLQATILKRLKPRGDRLTVVGDDAQAIYSFRAAEVKNILEFPAQFDPPARVVALERNYRSTQTILDASNAVIAMARERHEKRLWTDKVSSELPHLVTVDDEARQAQWVADKVLERREQGLKLTRQAVLFRTSSHAAPLELELTRRNIPFVKFGGLKFLESTHVKDVLSVLRWAENPRGRLAGFRVAQLLPGFGPASARRLLDAMSPSADPAQALRDFEAPRAASASWAALRDLVLQLISGSSWPMDLEEAVQWYAPHLERLYDDAPVRLSDLEQITRIAQGYGSRERFLTELTLDPPDASSDESGVPSKDEDYLILSTIHSAKGQEWNAVYLLNCVDGCMPSDLSTGAQAQIEEERRLLYVAMTRAKDHLAVMVPQRFYVTQQTRNGDRHLYASVSRFLPGKVVRHFEKVGPANQAQAPLPELVKPAMDVAAKLRKAWD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1923992 : 1933338

Synechococcus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_067272625.1\|1923992_1925084_+	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	1.4e-13	25.1
WP_067272627.1\|1925123_1926476_+	lipopolysaccharide biosynthesis protein RfbH	A0A0P0YLZ6	Yellowstone_lake_phycodnavirus	1.2e-49	34.5
WP_067272630.1\|1926522_1927479_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_067272633.1\|1927475_1928513_+	NAD-dependent epimerase/dehydratase family protein	A0A2H4UUK0	Bodo_saltans_virus	3.4e-25	28.8
WP_067272636.1\|1928509_1929529_+	2Fe-2S iron-sulfur cluster binding domain-containing protein	A0A0E3F6W9	Synechococcus_phage	6.7e-10	40.2
WP_067272638.1\|1929578_1930340_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	3.7e-05	26.9
WP_067272642.1\|1930634_1932209_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	6.7e-17	28.0
WP_067272645.1\|1932258_1933338_+	AAA domain-containing protein	H6WG28	Cyanophage	6.0e-33	39.4

DBSCAN-SWA_2

2980522 : 3019620

uncultured_Mediterranean_phage(25.0%)

tRNA,plate,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_067275050.1\|2980522_2981818_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.5e-94	52.1
WP_067282648.1\|2981925_2982897_-	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_067275053.1\|2982905_2983352_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_067275055.1\|2983425_2984100_+	JAB domain-containing protein	NA	NA	NA	NA
WP_067275063.1\|2984096_2984735_+	DNA mismatch repair protein MutS	NA	NA	NA	NA
WP_067275066.1\|2984929_2985568_+	hypothetical protein	NA	NA	NA	NA
WP_067275068.1\|2985679_2986063_-	hypothetical protein	NA	NA	NA	NA
WP_067275070.1\|2986215_2986644_-	group II truncated hemoglobin	NA	NA	NA	NA
WP_067275072.1\|2986678_2987491_-	MinD/ParA family protein	NA	NA	NA	NA
WP_082939029.1\|2987487_2988126_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	5.3e-13	32.5
WP_067275076.1\|2988390_2989260_+	chemotaxis protein CheR	NA	NA	NA	NA
WP_082938586.1\|2989317_2989989_+	chemoreceptor glutamine deamidase CheD	NA	NA	NA	NA
WP_067275080.1\|2990061_2991177_+	chemotaxis response regulator protein-glutamate methylesterase	NA	NA	NA	NA
WP_067275089.1\|2991369_2992872_+	ATP-dependent endonuclease	NA	NA	NA	NA
WP_067282651.1\|2992868_2993285_-	hypothetical protein	NA	NA	NA	NA
WP_157522344.1\|2993296_2993662_-	hypothetical protein	NA	NA	NA	NA
WP_067275095.1\|2993817_2994780_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_082939030.1\|2994809_2995994_-	oxygen-independent coproporphyrinogen III oxidase-like protein	NA	NA	NA	NA
WP_067275101.1\|2996004_2996610_-	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	NA	NA	NA	NA
WP_067275104.1\|2996675_2997410_-	ribonuclease PH	NA	NA	NA	NA
WP_067275106.1\|2997430_2998330_-	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_058936168.1\|2998326_2999295_-	serine/threonine protein kinase	B0FEC2	Escherichia_phage	1.5e-11	26.4
WP_067275108.1\|2999326_3000244_+	YicC family protein	NA	NA	NA	NA
WP_157522347.1\|3000256_3000424_-	hypothetical protein	NA	NA	NA	NA
WP_067275110.1\|3000457_3001027_-	exonuclease	A0A2L0UZL4	Agrobacterium_phage	1.0e-39	43.9
WP_157522350.1\|3001023_3001176_-	hypothetical protein	NA	NA	NA	NA
WP_157523068.1\|3001453_3002455_+	AAA domain-containing protein	NA	NA	NA	NA
WP_067275113.1\|3002695_3002947_+	hypothetical protein	NA	NA	NA	NA
WP_067275115.1\|3003056_3003680_+	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_067275121.1\|3003676_3004519_+	hypothetical protein	NA	NA	NA	NA
WP_067275123.1\|3004611_3006408_+\|tail	phage tail protein	NA	NA	NA	NA
WP_067275125.1\|3006490_3006934_+\|tail	phage tail protein	NA	NA	NA	NA
WP_067275127.1\|3007106_3008747_+\|tail	phage tail protein	NA	NA	NA	NA
WP_067275128.1\|3008743_3009223_+\|tail	phage tail protein	NA	NA	NA	NA
WP_067275131.1\|3009222_3010374_+	MGMT family protein	NA	NA	NA	NA
WP_157522353.1\|3010380_3010548_+	hypothetical protein	NA	NA	NA	NA
WP_067275134.1\|3010591_3011677_+	hypothetical protein	NA	NA	NA	NA
WP_067282652.1\|3011739_3012429_+	type IV secretion protein Rhs	NA	NA	NA	NA
WP_067275135.1\|3012440_3014045_+	hypothetical protein	NA	NA	NA	NA
WP_067275137.1\|3014049_3014433_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_067275140.1\|3014437_3016792_+\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_067275143.1\|3016791_3019620_+\|tail	phage tail protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011515

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP011514

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection