CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP009113	Rhodococcus opacus strain 1CP plasmid pR1CP2, complete sequence	1 crisprs	NA	1	0
NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	1 crisprs	PD-DExK	2	6
NZ_CP009111	Rhodococcus opacus strain 1CP, complete genome	2 crisprs	csa3,cas3,WYL,Cas14u_CAS-V,DEDDh,c2c9_V-U4,cas4,DinG,Cas9_archaeal	2	3

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009113_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009113_1

4188-4285

Orphan

Consensus_repeat	Method
GCATCCTCGACAGCATGGTCGACGCGAAGCTCGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009113_1

>merge|NZ_CP009113|1|4188-4285|CRISPRCasFinder
GCATCCTCGACAGCATGGTCGACGCGAAGCTCGCCACCAGCGCATTCGACGGCATCACCGTTGGCATGCTCGACAGCATGGTCGACGCGAAGCTCGCC

>NZ_CP009113|1|1|4188-4285|CRISPRCasFinder
GCATCCTCGACAGCATGGTCGACGCGAAGCTCGCC	ACCAGCGCATTCGACGGCATCACCGTTG
GCATGCTCGACAGCATGGTCGACGCGAAGCTCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009113.1\|WP_065493970.1\|2316_2592_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009113.1\|WP_065493923.1\|190_1021_-\|CopG-family-transcriptional-regulator	unknown	unknown	unknown
NZ_CP009113.1\|WP_065493929.1\|9904_11677_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|370445
NZ_CP009113.1\|WP_065493930.1\|12360_13212_+\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|272862
NZ_CP009113.1\|WP_065493932.1\|14169_14730_-\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	unknown
NZ_CP009113.1\|WP_065493928.1\|9051_9732_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NZ_CP009113.1\|WP_065493924.1\|2754_3738_+\|DNA-ligase	unknown	unknown	gnl\|CDD\|236599
NZ_CP009113.1\|WP_081315660.1\|6813_7131_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380100
NZ_CP009113.1\|WP_065493933.1\|14744_15173_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009113.1\|WP_081315667.1\|7202_8105_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NZ_CP009113.1\|WP_065493931.1\|13189_14173_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009113.1\|WP_155773136.1\|8099_8474_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009113.1\|WP_065493926.1\|5572_6736_-\|DUF2637-domain-containing-protein	unknown	unknown	gnl\|CDD\|378511

Protein	Function_ID	Function_description	E-value
NZ_CP009113.1\|WP_065493928.1\|9051_9732_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	3.57518e-44
NZ_CP009113.1\|WP_065493924.1\|2754_3738_+\|DNA-ligase	gnl\|CDD\|236599	PRK09632, PRK09632, ATP-dependent DNA ligase; Reviewed.	1.27878e-71
NZ_CP009113.1\|WP_081315660.1\|6813_7131_-\|hypothetical-protein	gnl\|CDD\|380100	pfam18064, ParB_C, Centromere-binding protein ParB C-terminal. This is the C-terminal domain found in centromere-binding protein ParB, which is used for stable segregation. The C-terminal domain has a ribbon-helix helix (RHH) motif with a C-terminal loop (residues 119-128) following helix alpha-2. The domain forms a dimer with the C-terminal of the beta chain. The function of the C-terminal domain is to bind to DNA.	0.0021741
NZ_CP009113.1\|WP_081315667.1\|7202_8105_-\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	1.83451e-33
NZ_CP009113.1\|WP_065493929.1\|9904_11677_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|370445	pfam09339, HTH_IclR, IclR helix-turn-helix domain.	0.000521531
NZ_CP009113.1\|WP_065493930.1\|12360_13212_+\|SAM-dependent-methyltransferase	gnl\|CDD\|272862	TIGR00027, Hypothetical_protein_Rv0893c/MT0917/Mb0917c., methyltransferase, TIGR00027 family. This model represents a set of probable methyltransferases, about 300 amino acids long, with essentially full length homology. Members share an N-terminal region described by Pfam model pfam02409. Included are a paralogous family of 12 proteins in Mycobacterium tuberculosis, plus close homologs in related species, a family of 8 in the archaeon Methanosarcina acetivorans, and small numbers of members in other species, including plants. [Unknown function, Enzymes of unknown specificity].	2.36001e-49
NZ_CP009113.1\|WP_065493926.1\|5572_6736_-\|DUF2637-domain-containing-protein	gnl\|CDD\|378511	pfam10935, DUF2637, Protein of unknown function (DUF2637). This family of proteins has no known function.	9.53408e-27

>NZ_CP009113.1|WP_065493924.1|2754_3738_+|DNA-ligase
MRLIAPMLATPGEPPEQMDGAWAAEMKYDGCRLLVAVGGDEPPVLWTRNLNVVTSSYPEVAEALTEAFGGRGRIVLDGEVVALVQGRKPSFARLQKRMNTLRPSTTVRRQVPVTYLPFDVLRLNGGNLMPAPYLERRTALTDLGHELHGAGLPIQVLPHWVGVESTVILDAAQNASMEGAIFKKVSSTYQPGKRARSWRKVLLRTRSSALVIGWIPGGGVQRNMVGSLVLGAYDDQGVIRYVGNVGTGFSMAMRRQLKEKLATLERRTSPLETEAAAAEEHGIVRWVEPVIVVDVDYREYRPGGLRHPSYKGQRGDLDPGSITRDSL
>NZ_CP009113.1|WP_065493970.1|2316_2592_-|hypothetical-protein
MTTWTLWLGALLVVGGSAALFKHQAVAARALWVLAVLAVLAFAAAAVGAVTASEVSLPLLLAVVIAIVATGALVAVTVPSKNPRERVSADG
>NZ_CP009113.1|WP_065493923.1|190_1021_-|CopG-family-transcriptional-regulator
MTETRPGRIPVGDPIALRFDPETKRRLEDMAEGIGPRRFGALIRVACRRLVTQPKAVGNGLAEQRRLSEALRAIPLVMLKIKLEPDTAQKFSALAAEHDTTVSALMRIALHRFLETPGRYKHPMLREADRTGLSDWVDVMVNPSSKQQIWRLAGRYGDKLNTALLRVALRRLLDEPGDLTTDLETIAPLRDLRPEIYPARANVHFDPPLRDRLDALAARVGSDRAELMRLAAKRVLDEPGLIEQAVNREIFRSEKNRKYLMARHARRQARRHTLHD
>NZ_CP009113.1|WP_065493926.1|5572_6736_-|DUF2637-domain-containing-protein
MNDLSIRAARIQVRALIAALIVAISIAIGITTGAFVLSFAVQRDLALQAGIPHYLTWIFPAIVDGAILGATIAVVALSKISGRATGKRFFLWLAVVVVFISVFGNAYHARRAGEEAARNVAAGMDLGFTPLTPTGASLIAIIPPLLVLAFTHGVGILIKAIGTAHTEYNALCNDIASRAVEERETSGAVSSRLNPQVIPDRNGQHSFAINDMNAGNASNAGAYVGAAETQVAGVRTSPDATNDDIAEAGSTRVDGCVGEDDVVAESVANDQDIARNELATAETETSVLPDELQTTEYLLAFIESSKLDPMVKETARLKIEHPDATFAALAEATGEKWASTALRRYNKAKDLAVDAGFRTPPLPLTDEATDNGSDESDAAPYELVGAR
>NZ_CP009113.1|WP_081315660.1|6813_7131_-|hypothetical-protein
MSALRRDRNKAATDLASTAAAAQQPAEPEKKPSNKPTTVYIAPDVLKEARLAFKATQSAEADRNWSHFVEKALADATQRRAVQHNDGNAFEGEDKPLPPGRPLAD
>NZ_CP009113.1|WP_081315667.1|7202_8105_-|ParA-family-protein
MHRVTAVINGKGGVFKTTLAANISGLLAESGYKVLLVDLDPQGNIAEDLGYTYGEIDDEGKNLAQALSFGDPITPVRDIRPNLDIIPGGTHLSMATAALASKATKDPIGAKLALATALAPLAGEYDMVLIDCPPGDETLQTAAAAAAKWLLVPTKTDGSSRKGMAAVAARLTSVMDVNEELELLGVVLVGVGANSTSVQRTAREGIATAFGGDADDVVFEKMVRHSEATALAIRERGVLVHELDDVVQSGPKWYEVVRGSAKAQEHAPKSAKEVAADLLAVCQEMVQRITEAEAAEVAAS
>NZ_CP009113.1|WP_155773136.1|8099_8474_+|hypothetical-protein
MQRDRIALRDYVRARWWHRRLPRYPGAGFTVNAGIAINDGNCCNARITCVAGVAGVTSVAGIANVTGNAVIASITVIPGVSSHQQCLQCFYAVQMWYARIAFNTIIDGYALQTAMPVLLATLAN
>NZ_CP009113.1|WP_065493928.1|9051_9732_-|MBL-fold-metallo-hydrolase
MVLTLDQPYTGHVSPESNPQVRLIPGGRIIKMSVAAGDNNVYLIECTTTGQALLIDAANEPERVIALVKQEAPDLRLVVTTHQHIDHWWALKDVVAATGSPTAAHPLDADALPVAPDRLLVDGDTITIGALTFEVIHLRGHTPGSLALAVTEPDGGRTHLFTGDSLFPGGVGKTAEPENFATLIADVETKIFDRHPDNTVVYPGHGDDTTLGVERPHLAEWRERGW
>NZ_CP009113.1|WP_065493929.1|9904_11677_-|helix-turn-helix-domain-containing-protein
MRVDPSRKHNYDTSMVAPKQAPDYPWAIYLASSDHRFRLLVFDFDTANFGADQARTDSDRLAAHLDELGVHYLRAHSGSTGGQHIWVRLGEDGADAAAVGELNRVLDQHYATFDNSPLSKPRRGVVRPPGAPHRDGGRSVPYLAGAELQQALERVGRGTTPEVVTWLLARHPHTKPMGTISAAVRATPIRISDPATDPHLDRPRRPLSAATQELLDTAPGKRADRSAIAHSIFLGMACAGHTLNDARTAAESAPGLVRLREDRDSGRDDLARQWDRALQRAATFAYLPEGNNRQEPLDEDLDTIERVLAVHAARFAQPGGESDERILYALITFARAARTRTLDIDCRRLAQRTGLAASTISRRLRVLAQTGWVTQTYAAAGTRAASWTLNLPPKGWEDPDATQGNPPPALEPASTLLTHHTHDLWSPRPGLGATAARIHWALLGGARTTKEIAGVTGYSLKTAEKTLRRLSRLNLVGPGPRSAESVKGQLHSAAKELGLAEVSAGRRERHIIDRELFAWWNDEQAWRRRKGKKRGPKRNAGMATTLALPIDGPARIKYGRFPTKPGGRADYRTARDIVRGNLAPAERVAA
>NZ_CP009113.1|WP_065493930.1|12360_13212_+|SAM-dependent-methyltransferase
MSEEIQSEGDISATAVAVAHFRALETGRDDRLFSDPLAAHFVAASGLPIGSIGLSDVTASRVYQSVVARTKFLDDALREAAASGAVKQLVVLGAGLDTRARRLALPGVESAYELDLPHLFSFKRRALDSAPTKPIDAALPVIDVAADLLADDWGTHLVAAGFDATLPTAWVVEGVFIYFTTDQNAQIMKQLMQLSAPGSRLLAVHFGIGSLEEAQSKEMAARTEQGGYGFKSVVANPVDWLAEWGWETESVSIKDFAQTLGREVPYLEQPGHEVAWLIASRLP
>NZ_CP009113.1|WP_065493931.1|13189_14173_-|hypothetical-protein
MTIFITAVISLAVLAVASCRIVVDGAATRSRGPLAGLSNPVTQLLLCLGFAKLCRVPVITDDMINPRLQHFTGVANIMSLAGMTWAALVAIPLMGIAAYITGGVQFSARLQLLQAGLIVGVMTIAFLYSPMADQPTSYMTSDFPVTGSVLLYWLAFLLPILTSCGVTAYHCAASLVLVRRGLLARALGALFCAAVVGILYCSHKVVDLFLQYSGVDNAYSHHAKSISLVLVLVALAFAALAAGIYAGAQLPQRIQRYRLLRKYGRDWLAARANTPVVVLDSSHELKYTRWACWAAARTPTAAFHLQVELADASDLAPKQPVTAIATR
>NZ_CP009113.1|WP_065493932.1|14169_14730_-|ImmA/IrrE-family-metallo-endopeptidase
MNDLAGQDEDREIAERAVARMPMQRPWSLDRLIAELSLQRGRPIVTAPLQRKPKLSGEVSGLWVPREDRDLVFYRAGATGMQRDAIICHELGHIVLSHGRLSREAVARYNSRLNSRLPREMITRFSTPLCLMRSQYEEPVERQAEWFSRLLLVKGAELTAPLVPEDASPRHRRMLERAARAFGWDQ
>NZ_CP009113.1|WP_065493933.1|14744_15173_-|hypothetical-protein
MSNQIPLSQRLDLLFVLWCKSSDSPAPYSDIAAEVSRRTGVVLTADEVEDIRFGHRLPDSAVAIAIAEALGWDEPVYLSDEPAQYVEYFNNLQTLLVQRDTKTVLVGGFRSSTEDLSQEARDELHELLGEIEAAEDGRRTTK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_CP009113	Rhodococcus opacus strain 1CP plasmid pR1CP2, complete sequence	4223-4250	0	1.0
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	2029291-2029318	5	0.821
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4766720-4766747	6	0.786
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	KU682439	Stenotrophomonas phage vB_SmaS-DLP_6, complete genome	9670-9697	6	0.786
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	852701-852728	7	0.75
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	1675209-1675236	7	0.75
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	1477765-1477792	7	0.75
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	96399-96426	7	0.75
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	95468-95495	7	0.75
NZ_CP009113_1	1.1\|4223\|28\|NZ_CP009113\|CRISPRCasFinder	4223-4250	28	NZ_CP010863	Marinovum algicola DG 898 plasmid pMaD8, complete sequence	45807-45834	7	0.75

1. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_CP009113 (Rhodococcus opacus strain 1CP plasmid pR1CP2, complete sequence) position: , mismatch: 0, identity: 1.0

accagcgcattcgacggcatcaccgttg	CRISPR spacer
accagcgcattcgacggcatcaccgttg	Protospacer
****************************

2. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.821

accagcgcattcgacggcatcaccgttg	CRISPR spacer
accagcgtattcgacggcatctcggagg	Protospacer
*******.************* * *  *

3. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.786

accagcgcattcgacggcatcaccgttg	CRISPR spacer
gcctgcgcatgcgacggcatcacccacg	Protospacer
.** ****** *************  .*

4. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to KU682439 (Stenotrophomonas phage vB_SmaS-DLP_6, complete genome) position: , mismatch: 6, identity: 0.786

accagcgcattcgacggcatcaccgttg	CRISPR spacer
ccgagcgcattcgaccgcatcaacgtgc	Protospacer
 * ************ ****** ***

5. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 7, identity: 0.75

accagcgcattcgacggcatcaccgttg	CRISPR spacer
cacagcgcattcgacgtcatcgccggcc	Protospacer
  ************** ****.*** .

6. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 7, identity: 0.75

accagcgcattcgacggcatcaccgttg	CRISPR spacer
gcgctcgccttcgacggcatcaccgtct	Protospacer
.*   *** *****************.

7. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 7, identity: 0.75

accagcgcattcgacggcatcaccgttg	CRISPR spacer
gcgctcgccttcgacggcatcaccgtct	Protospacer
.*   *** *****************.

8. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.75

accagcgcattcgacggcatcaccgttg	CRISPR spacer
gcgctcgccttcgacggcatcaccgtct	Protospacer
.*   *** *****************.

9. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 7, identity: 0.75

accagcgcattcgacggcatcaccgttg	CRISPR spacer
gcgctcgccttcgacggcatcaccgtct	Protospacer
.*   *** *****************.

10. spacer 1.1|4223|28|NZ_CP009113|CRISPRCasFinder matches to NZ_CP010863 (Marinovum algicola DG 898 plasmid pMaD8, complete sequence) position: , mismatch: 7, identity: 0.75

accagcgcattcgacggcatcaccgttg	CRISPR spacer
cgcagcgcatccgacggcatcatcgaaa	Protospacer
  ********.***********.**  .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP009112

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009112_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009112_1

98306-98480

Orphan

Consensus_repeat	Method
GCCGTCTTCTTCGCCGGAGCCTTCTCCACGGCCGTCGTCT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP009112_1

>merge|NZ_CP009112|1|98306-98480|PILER-CR
GCCGTCTTCTTCGCCGGAGCCGTACCCGCCGCCGCTCCCTTCACCGGAGCCTCCTTCTCGACAACCTTCTCCACGGCCGTCGTCTCCACGGCCGTCGTCTCCCCTGTCGTTTTCGCCCCTGCCGTCTTCCCCGCTGCCGTCTTCTTCGCTGGAGCCTTCTCCACGGCCGTCGTCT

>NZ_CP009112|1|1|98306-98480|PILER-CR
GCCGTCTTCTTCGCCGGAGCCGTACCCGCCGCCGCTCCCT	TCACCGGAGCCTCCTTCTCGACAACCTTCTCCACGGCCGTCGT
CTCCACGGCCGTCGTCTCCCCTGTCGTTTTCGCCCCTGCC	GTCTTCCCCGCTGCCGTCTTCTTCGCTGGAGCCTTCTCCACGGCCGTCGT
CT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009112.1\|WP_155773081.1\|105213_105795_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NZ_CP009112.1\|WP_065493435.1\|91567_91843_+\|DUF4193-domain-containing-protein	unknown	unknown	gnl\|CDD\|379391
NZ_CP009112.1\|WP_081315528.1\|94481_95957_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271187
NZ_CP009112.1\|WP_065493440.1\|102014_102368_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009112.1\|WP_065493437.1\|95953_96394_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009112.1\|WP_065493443.1\|104001_104580_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009112.1\|WP_081315533.1\|102364_102826_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009112.1\|WP_065493444.1\|105845_108104_+\|catalase/peroxidase-HPI	unknown	unknown	gnl\|CDD\|237891
NZ_CP009112.1\|WP_081315527.1\|89578_90232_+\|RES-family-NAD+-phosphorylase	unknown	unknown	gnl\|CDD\|378053
NZ_CP009112.1\|WP_065493434.1\|88868_89579_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009112.1\|WP_065493447.1\|116377_116866_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|182510
NZ_CP009112.1\|WP_065493428.1\|83928_84981_+\|4-hydroxy-2-oxovalerate-aldolase	unknown	unknown	gnl\|CDD\|181282
NZ_CP009112.1\|WP_155773129.1\|100811_101387_+\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl\|CDD\|274424
NZ_CP009112.1\|WP_065493446.1\|113155_114952_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173842
NZ_CP009112.1\|WP_065493445.1\|108780_112050_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP009112.1\|WP_065493432.1\|87997_88450_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009112.1\|WP_065488362.1\|91865_93149_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_CP009112.1\|WP_065493429.1\|84977_85772_+\|4-oxalocrotonate-decarboxylase	unknown	unknown	gnl\|CDD\|132262
NZ_CP009112.1\|WP_081315534.1\|115364_116093_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP009112.1\|WP_081315637.1\|97147_97696_+\|Tellurium-resistance	unknown	unknown	gnl\|CDD\|226595

Protein	Function_ID	Function_description	E-value
NZ_CP009112.1\|WP_155773081.1\|105213_105795_+\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	2.33843e-33
NZ_CP009112.1\|WP_065493435.1\|91567_91843_+\|DUF4193-domain-containing-protein	gnl\|CDD\|379391	pfam13834, DUF4193, Domain of unknown function (DUF4193). This domain of unknown function contains four conserved cysteines and a conserved histidine, including a CXXXXH motif.	3.0677e-37
NZ_CP009112.1\|WP_081315528.1\|94481_95957_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271187	cd01187, INT_tnpB_C_Tn554, Putative Transposase B from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase B from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain containing six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	7.90267e-12
NZ_CP009112.1\|WP_065493445.1\|108780_112050_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.31552e-80
NZ_CP009112.1\|WP_081315527.1\|89578_90232_+\|RES-family-NAD+-phosphorylase	gnl\|CDD\|378053	pfam08808, RES, RES domain. This presumed domain contains 3 highly conserved polar groups that could form an active site. These are an arginine, glutamate and serine, hence the RES domain. The domain is found widely distributed in bacteria. The domain is about 150 residues in length.	3.96075e-08
NZ_CP009112.1\|WP_065493447.1\|116377_116866_-\|acetyltransferase	gnl\|CDD\|182510	PRK10514, PRK10514, putative acetyltransferase; Provisional.	7.05182e-47
NZ_CP009112.1\|WP_065493428.1\|83928_84981_+\|4-hydroxy-2-oxovalerate-aldolase	gnl\|CDD\|181282	PRK08195, PRK08195, 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated.	0
NZ_CP009112.1\|WP_155773129.1\|100811_101387_+\|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl\|CDD\|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	1.485e-16
NZ_CP009112.1\|WP_065493446.1\|113155_114952_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173842	cd01153, ACAD_fadE5, Putative acyl-CoA dehydrogenases similar to fadE5. Putative acyl-CoA dehydrogenase (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	4.91847e-168
NZ_CP009112.1\|WP_065493444.1\|105845_108104_+\|catalase/peroxidase-HPI	gnl\|CDD\|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NZ_CP009112.1\|WP_065488362.1\|91865_93149_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	9.75345e-136
NZ_CP009112.1\|WP_065493429.1\|84977_85772_+\|4-oxalocrotonate-decarboxylase	gnl\|CDD\|132262	TIGR03218, 4-oxalocrotonate_decarboxylase, 4-oxalocrotonate decarboxylase. Members of this protein family are 4-oxalocrotonate decarboxylase. Note that this protein, as characterized (indirectly) in Pseudomonas sp. strain CF600, was inactive except when coexpressed with DmpE, 2-oxopent-4-enoate hydratase, a homologous protein from the same operon. Both of these enzymes are active in the degradation of catechol, a common intermediate in the degradation of aromatic compounds such as benzoate, toluene, phenol, dimethylphenol (dmp), salicylate, etc. [Energy metabolism, Other].	1.29393e-79
NZ_CP009112.1\|WP_081315534.1\|115364_116093_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.37666e-06
NZ_CP009112.1\|WP_081315637.1\|97147_97696_+\|Tellurium-resistance	gnl\|CDD\|226595	COG4110, COG4110, Uncharacterized protein involved in stress response [General function prediction only].	3.36372e-74

>NZ_CP009112.1|WP_081315637.1|97147_97696_+|Tellurium-resistance
MSLAKGGDTGTMRINLNWTRGRRGLLGNGAIDLDLACLYQLNNGSKGVVQALGNAFGDLHYPPYIALDGDDRSGTNTGGENLHINLAHLADFKRILIFAYIYDGTPNWSAADGVVTLYPPHGPQVEVRLDSPDNRARSCAIALLKNEKNEFTVTREVQYINGTQSEISKAYRWGMKWTAGRK
>NZ_CP009112.1|WP_065493437.1|95953_96394_+|hypothetical-protein
MSRGNPDNLRRAAAAKSAAAHSRADHGIREMIRRNVPVTFRGLAQTAGVSLDFLYRNPEIRHRVEQLRTQQRSAPPAPSPPADPDHPSSVVRTLTVQITELKRRHREKVQTLKSALEAVHGENLELRRRLGGHRPHPAEISPSSNC
>NZ_CP009112.1|WP_081315528.1|94481_95957_+|tyrosine-type-recombinase/integrase
MGSRRLLENLRDTSGRFRGDVLESLWAEMPDRFRTIDLASNDLDTDDLTAFLTDPRGPGFRIRFGQLPADMDREMAWCCWRIAELGGRVPVGVLRSLIRWLAATVEDHPELSGSLMRAAPREWERSIVGSPSRCTLLMIEGGGLGDEQIMRILMLVARTGRRISEIRMLDREPLLPLDRLGGSTGPADGAFVAKLRYQQTKIEQAPDTVLVDAEIVAIIDEQRRWADQHLGPRWARGVTPKYLFLGHNMNRNADKPFPPSRINQTLAVFARRLDVRDSAGRLVDFNRTHRFRHTKATSLLNAGVPLHVVQRYMGHVSPTMTMEYAETLAETHEREFLRYRKVTADGRDLPVDTRDLYDMLELDKRTDRILPNGWCLLPPRQACDKGNTCLTCDKFATDASFLPELRTQQHHTLQLIDERRQAFAARTGQEMSPDNVWLAGRTQEHDALGRIIDTLEQTGHRTDSDGRAVRGAGVAARTDALAAEHEQERRP
>NZ_CP009112.1|WP_065488362.1|91865_93149_+|IS256-family-transposase
MTDVIDLEAESNSARVGVSDARLQELVDQARADGLQLTGEGGLLAKLTKLVVESALEGEMDDHLGYGKNDSVGRGSGNSRNGRRAKTVLTEAGPVELEVPRDRESSFEPKIVAKRQRRLTGVEDMVISLSAKGLTTGEISAHMAEVYGAEVSKQTISTITERVMDGMLEWQNRPLDQVYPVLFIDCIHVKIRDGNVANRPIYVVMGVTADGTRDILGLWAGEHGDGEGAKYWLRVLSELKNRGVQDVLIVVCDGLKHLPDSIGQVWPQTIVQTCVVHLLRNTYAYASRKDWAEIAKDLKPVYTAPSEQAALDRFAEFSDKWEKRYPAIIRMWTNAWAEFVPFLQFDHAIRQVIYTTNAIESVNARIRRAVKARGHFPTEAAALKCVYLAIMSLDPKGTARQRWSNRWKAALNAFEITFDGRLSAGRK
>NZ_CP009112.1|WP_065493435.1|91567_91843_+|DUF4193-domain-containing-protein
MATDYDAPRVTESDEPDTSLEQLTASRKDTQSPAVDVEDTDTAESFELPGADLSGEELTVRVIPKQADEFTCYLGLSGVVCDAAGTVRTTV
>NZ_CP009112.1|WP_081315527.1|89578_90232_+|RES-family-NAD+-phosphorylase
MPNIDPPAGLLRPAHRTVLTAGTVVWRVHSSHRAPHAPNPTAQPDELAGGRFDSLDGSYAYLYLADSPDGAIAETICRDLPLDPSIARIVPASAVADRTLTALTVTRTLTVAALHGPHLAAVGQDLWLTKCDARHYVTTRRWTHAIRTADPDLDGLAYRPRHNEDTLAWILTTDPAITPHPDLTVDPTTTPLPLDHGPGRDLVARIIADHSAILSPT
>NZ_CP009112.1|WP_065493434.1|88868_89579_+|hypothetical-protein
MSTHRSISPRRHHKLAGYRLRRDNATGRYTHAGDRPQSTPSPDERRLSDLSTPELIDVVASELAARPEMHLVRNQVTALLAMAPTLTDRTQAARIGADLVDDAIAQAEIEQAARRHILDHPMLTAGQVAAVLHRPASDRTVASRLRTTGKVVALLVGNSYRYPVFQFNEATASVRDTVAAINTTLGAAADPWGVASWWLTPSTRLPEGQTPADLAADPDPAAGQKLERLASAVLPD
>NZ_CP009112.1|WP_065493432.1|87997_88450_+|hypothetical-protein
MKDSSRPRLPRLLAAGIASLATLTAAIVGAPSVSAAPVDTVLPVPVAGNTLSFQYATWMGICQGRVIARTDTATPGLTYFRMETGCTGTVHWRNLTTGAAGDAEVRASNSPQSPPPAAAATGSGVLVATITLGIPYSTTFWPGMGMWTAP
>NZ_CP009112.1|WP_065493429.1|84977_85772_+|4-oxalocrotonate-decarboxylase
MSTDTTAWNIDTAAEVLLRAEKTRTDRHPITDDWPELDVETAYQVQAALIARKVAQGEKIVGVKLGLTSRAKQERMGITSPLTAWLTDGMVLEAGVPIPTGELIHPRVEPEIVFVLGDRLEGPGATAATAMAAVRSVYAGIEVIDSRYIDFKFTLPDVLADNASSSRFVIGGVERDPRDLDLALEACVLSVDGTVVDSATGAAVQGHPAEALALAANALAERGLALEAGWIVLTGGMTDAVFVEPGKQIVAEFTHLGSVTVSGS
>NZ_CP009112.1|WP_065493428.1|83928_84981_+|4-hydroxy-2-oxovalerate-aldolase
MTATENAVSIRLTDTTLRDGSHAVSHQFTVAQVRAVVRGLDAAGMPVIEVTHGDGLSGSTFNYGFSAVDEIELIAAAVEEAKTAKIAVLLLPGLGTVADLRKAHDVGASVARIATHCTEADVSIQHFGAPRDLDMETVGFLMLSHRTTPENLATQARIMADAGCQCVYVVDSAGALLPDGVADRVAALVAELGSDVQVGVHAHQNLSLGVANSIAGVKAGARQIDGTLCALGAGAGNSPTEILAVAFERLGVATGVDTDSILTVAEEVAKPFIPRLPVADRNSIIQGKYGVYNSFLFHAERAAQRYGVPAHEILARVGEAGYVGGQEDMIIDVAIELAGQSSNRKEAVTV
>NZ_CP009112.1|WP_155773129.1|100811_101387_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MRLTYGVGMGSPITSLYSRVAQDFTDRLLGCPQDRWNSASPCPGWTAWDVAAHVVGNHRRACAGLRGNDYRVPTAGEDVVAAWLDATAGVQASPESEATAQQVLGAEFGYLPFEHFVRRMACADTLIHTWDFARATGQDEHLDPEAVELARTFLVAEDDRIRLPHAFGAKVAPTDNADAQTQLLNFLGRAT
>NZ_CP009112.1|WP_065493440.1|102014_102368_-|hypothetical-protein
MSPKRGERVAPPAAGELWELRFATSDAAKGWDELCRQAPANTLVAYEELRRRTVVGESTTRHHRLKGRLATGVHNGVEMEQWQYEVTAGARVWYVLDIEHRTLWLKHAGTGHPKQTE
>NZ_CP009112.1|WP_081315533.1|102364_102826_-|hypothetical-protein
MGEVPFSDIQNKGKATLSEWQRSGARPLRVTRRDDEDLVLMTAVRADQEREVLAAATAMVDALLHSDDSALVRKVVAAAFPWVSYLSAEELVDFVDELIASLRAGSSLDNPAPPARTIETWRHTAEVYADPELARILSAPSEGDFGAVPVPEL
>NZ_CP009112.1|WP_065493443.1|104001_104580_-|hypothetical-protein
MEPAAEELLLTDDELIGSGWNPDEDTDPEAAEVQASSQPECSSQSWTLKTPEVVDDAASAWHFDSAAEVELITSQAWTYSSAEEASAALAAYRDAASRCVSWDTADTGSGYAYHEQQELFDIPVAEEALGRHGTTSSIKYPEVGSFPMYWVAARDGSQVVQVTYRPGSLLSGVEGRARVEALAATAASKMQD
>NZ_CP009112.1|WP_155773081.1|105213_105795_+|transcriptional-repressor
MPLVWHRLIQCRRKGGSIPASVRNSRNHNAAGLSTRILTNSRNVIHSVRVLSTTDYTDRLRLAGLRVTRSRAAVLEAVHAHPHSGTDTILDAVRVVLPGVSRQAVYGVLHVLTARGLVRRIQPAGLVARYESRVGDNHHHDVCRSCGAIADVDCTIGETPCLAASHDNGYTVDEAEIFFWGLCLNCSTSQQRT
>NZ_CP009112.1|WP_065493444.1|105845_108104_+|catalase/peroxidase-HPI
MSKTNQALTEEHPPIAEAQTEPAQSGGCPVAHGGLKHPTQGGGNRDWWPNQLNLKILQKNPAVRNPMDEDFDYTRELENLDFEALKRDIEEVMTTSQDWWPADYGHYGPLFIRMAWHAAGTYRVSDGRGGACAGMQRFAPLNSWPDNANLDKARHLLWPVKKKYGKTISWADLIVFAGNVALESMGFATFGFGAGRVDQWEPEEDVYWGPELTWLGDERYTGDRNLEKPLGAVQMGLIYVNPEGPNGNPDPVAASRDIRETFARMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEEQGLGWKSAFGTGKGGDTITSGLEGAWTPTPATWDNSFLETLYGYEWELSKSPAGAYQWIPKDGAGAGTVPDAHDAAKTHVPVMLTTDLALRIDPAYEKITRNWLENPDQLADDFAKAWYKLTHRDMGPIGRYLGPLVPGETLLWQDPIPAVTHELIDAGDIASLKSQILESGLTVAELVSTAWASASSFRGSDNRGGANGGRIRLEPQASWEVNNPAELAQVVRTLEGIQESFNTAQTGNKRVSFADLVVLGGAAAVEQAAKDGGHDIEVPFTPGRTDATQEQTDVESFAALEPTADGFRNYLGDGNRLPAEFLLVDKANLLTLTAPELTVLVGGLRVLGANYNTRSEEGVFTSKPGTLTNDFFANLIDLGTTWAPRSTDSEIYEGRDRVTGEVKWTGTRVDLVFGSNSELRALAEVYASDDAQQKFVRDFVSAWNKVMNLDRFELA
>NZ_CP009112.1|WP_065493445.1|108780_112050_-|protein-kinase
MADIDPIETQRDVVGTSVTAELVAVGFEDADEIGRGGFGVVFRCKQTVLDRTVAVKVLTEDLDDEDRERFFREQRAMGQLSGHPNIVDILQVGTTSSDRPFIVMPYHARGSLDARIRLRGPLPPEQSLRLGVKLAGAVETAHRHGILHRDVKPANILLTEYEEAELTDFGIAHIADGFETATGTITGSPAFTAPEVLAGAPPSAASDVYGIGATLFCAMTGHAAFERRSGEQVMAQFVRITTEPLPNLRAQGIAADIGAVVERAMSGNPADRPPTAAALGDELRNVQRRLGFAVDEMALQRTPGAERPESIPHSRGRGLGTGPIGTKGHLPLELTSFVGRRRELTEAKNLLTASRLLTLTGIGGVGKTRLGLRVAAGAQREFGDGVRLIELGELTDESLMVDVVAAALGMRIQSTRRTDDVLVEFLAPRELLLVLDNCEHVVDAAAQLSEMLLRFCPRLRILATSREALGIGGEAVLRVPPLTVPGPDSEPSLQGLPRYDAVTLFADRASAAVPTFGLTDDNRTAVARICQRLDGLPLPIELAAARMRAMSPAQILQKLSDRYALLTRGSRDAPSRQQTLRLCIDWSHDLCTPQEQLVWSRLSVFAGSAELDAAEQVCGDGFPPEELLDLLTSLVDKSILIREEAHGAVQFRLLETLRDYGREQAQRSGEYPVLLRRHRDWYLRLALDAEADWISPRQLEWIARLGREQPNLRETLEYCVSESPDVGLRIVTALYLFWSTRGLYSEGRRWLDRFLAGQTGQSAAADHAKLLYAASMLAELQGDLQAGEALVREGRTLAEGTSDSETESLIDHADGLLAFFGGDLTRARPLLERSLAAFRRQGDTALQVEALWAMGLLHASSGEPDRAISCYQQALTITESRGESVHRAYALCAMAILIWQKGDVGQATALLDQGLVLLARLVEDPVGSAMCLEALAWVAGGENQAHRAAALMGAAKALGAAVGSSPTFVPNLRAFHDQCEHQTRQRLGEKAYRRAVREGADLALGDAVAYALGEHPSDTASPTGLDAQLTTREKQVAELIAEGLTNRAIATRLTISPRTAQGHVEHILVKLGFTSRAQVAAWVVERKGP
>NZ_CP009112.1|WP_065493446.1|113155_114952_+|acyl-CoA-dehydrogenase
MTDVLSRRDIDFLLYEWLDVVSLTSRKRFSEHAKDTFDAVLDLSADIAHKHFATHNKKADANEPTMRPDGTVEMIPEVKKALEVYASAGLIAGQFDENVGGMQLPTTVARAAMAWFQAANAATAAYPFLTIANANLIATYGTEQQIDDYVRPMLEGRYFGTMCLSEPHAGSSLADISTRAVRQDDGSYRLTGTKMWISGGDHGLTENIVHLVLAKTPGGGPGVKGISLFIVPKYLPDADGAVGDRNDVTLTGLNHKMGNRGTTNALLSFGDGLHSPAGRSGAVGFLIGEEHHGLSYMFHMMNEARIGVGFLAISLGYVGYLKSLEYAKVRTQGRPLGSRDPSSPPIPLIEHTDVRRMLLAQKSYVEGALALGLYCSFLVDEQDTATDESAAAEAKLLLDVLTPIVKSWPSQWCLEANSLAIQVHGGYGYTRDYDVEQFYRDNRLNQIHEGTHGIQGLDLLGRKVTMQDGAGLTVLGSKVTATIERGRALGGDTARYAAELDVVWNRIVEVTATLWSAGDSTTTLANSSVYLDTVGHAVIGWMWLEQLAAVDGKDGDFYAGKRHTAQYFYTYELPKVGAQLDLLASLDRTTLDMKPSWF
>NZ_CP009112.1|WP_081315534.1|115364_116093_+|transposase
MRPWWRHSLLSTPIAPAGMAYDTPTRAAPRDRGLGRMPRAVRCRIPIFIAADTSDAGRPWSSSTTSRIRYTGHWTLRIDRTTSSESPSCIPAAETTDNGGSASHRARRLVNQLHALPRELFPGGMERDFGTEVPPASSRRFCRRPRRTQCARMSLSISSETFAGPGSRSRTSPPKPRPSSLPAHQAAEDSRCRRCHAAHILARTGDPTRFVNEAAFASYSGTALIEVASADKQRHRLSRSGD
>NZ_CP009112.1|WP_065493447.1|116377_116866_-|acetyltransferase
MSASKGLVLRPCKGEAEWPTLVRIWRSAVEASHDFLTPEDVAFYESRMLSDYFPAVELTVAEVEETPVAFSGLAGNSLEMLFVDSTYRGHGVGSALLLRAIEYHPDLRLDVNEQNPQAVGFYQHYGFVVLSRSATDGDGRPFPILHMGQAAVGAADTPIGLS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP009112_1	1.1\|98346\|43\|NZ_CP009112\|PILER-CR	98346-98388	43	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	98327-98369	0	1.0
NZ_CP009112_1	1.2\|98429\|50\|NZ_CP009112\|PILER-CR	98429-98478	50	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	98391-98440	0	1.0
NZ_CP009112_1	1.1\|98346\|43\|NZ_CP009112\|PILER-CR	98346-98388	43	NC_012520	Rhodococcus opacus B4 plasmid pROB01, complete sequence	477813-477855	1	0.977
NZ_CP009112_1	1.1\|98346\|43\|NZ_CP009112\|PILER-CR	98346-98388	43	NC_008271	Rhodococcus jostii RHA1 plasmid pRHL3, complete sequence	83782-83824	1	0.977

1. spacer 1.1|98346|43|NZ_CP009112|PILER-CR matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 0, identity: 1.0

gtacccgccgccgctcccttcaccggagcctccttctcgacaa	CRISPR spacer
gtacccgccgccgctcccttcaccggagcctccttctcgacaa	Protospacer
*******************************************

2. spacer 1.2|98429|50|NZ_CP009112|PILER-CR matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 0, identity: 1.0

ccacggccgtcgtctcccctgtcgttttcgcccctgccgtcttccccgct	CRISPR spacer
ccacggccgtcgtctcccctgtcgttttcgcccctgccgtcttccccgct	Protospacer
**************************************************

3. spacer 1.1|98346|43|NZ_CP009112|PILER-CR matches to NC_012520 (Rhodococcus opacus B4 plasmid pROB01, complete sequence) position: , mismatch: 1, identity: 0.977

gtacccgccgccgctcccttcaccggagcctccttctcgacaa	CRISPR spacer
gtacccgccgccgctcccttcaccggagcctccttctcgacga	Protospacer
*****************************************.*

4. spacer 1.1|98346|43|NZ_CP009112|PILER-CR matches to NC_008271 (Rhodococcus jostii RHA1 plasmid pRHL3, complete sequence) position: , mismatch: 1, identity: 0.977

gtacccgccgccgctcccttcaccggagcctccttctcgacaa	CRISPR spacer
gtacccgccgccgctcccttcaccgaagcctccttctcgacaa	Protospacer
*************************.*****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

24222 : 64441

Mycobacterium_phage(30.0%)

transposase,integrase

attL 50030:50089|attR 55155:56613

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005261528.1\|24222_25428_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_065493389.1\|26203_27286_+\|integrase	tyrosine-type recombinase/integrase	A0A0K1Y646	Mycobacterium_phage	1.5e-07	30.4
WP_065493390.1\|27251_29165_+\|integrase	tyrosine-type recombinase/integrase	A0A1U9WS15	Gordonia_phage	1.4e-05	31.2
WP_065493391.1\|29161_29467_+	hypothetical protein	NA	NA	NA	NA
WP_081315517.1\|29917_30364_+\|transposase	IS200/IS605 family transposase	I4AZM1	Saccharomonospora_phage	2.2e-37	57.1
WP_065493394.1\|30688_31402_-	HNH endonuclease	NA	NA	NA	NA
WP_065493395.1\|32041_32266_+	hypothetical protein	NA	NA	NA	NA
WP_065493396.1\|32325_32565_+	hypothetical protein	NA	NA	NA	NA
WP_065493397.1\|32808_33300_+	hypothetical protein	NA	NA	NA	NA
WP_037235132.1\|33832_34078_-	transcriptional regulator	NA	NA	NA	NA
WP_065493398.1\|34896_35217_-	hypothetical protein	NA	NA	NA	NA
WP_155773078.1\|35538_36387_-	hypothetical protein	NA	NA	NA	NA
WP_065493402.1\|37655_38708_-	Ldh family oxidoreductase	NA	NA	NA	NA
WP_065493403.1\|38793_39114_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_065493404.1\|39157_40576_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_065493405.1\|40624_41095_+	cupin domain-containing protein	NA	NA	NA	NA
WP_065493406.1\|41133_41451_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_065493407.1\|41447_42644_+	lactonase family protein	NA	NA	NA	NA
WP_081315520.1\|42691_43576_+	CoA ester lyase	NA	NA	NA	NA
WP_065493409.1\|44043_44448_-	universal stress protein	NA	NA	NA	NA
WP_065493410.1\|44462_45881_-	citrate:proton symporter	NA	NA	NA	NA
WP_065493411.1\|45968_46667_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_065493412.1\|46767_46959_+	hypothetical protein	NA	NA	NA	NA
WP_081315521.1\|46985_48398_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_065493413.1\|48568_48895_+\|transposase	transposase	A0A1B3AZF8	Gordonia_phage	1.7e-15	50.0
WP_065491468.1\|48891_49821_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	2.2e-39	39.9
50030:50089	attL	NA	NA	NA	NA
WP_065493414.1\|50063_51371_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.7e-213	84.5
WP_155773128.1\|52177_52813_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2L1IVA1	Escherichia_phage	2.5e-07	30.6
WP_155773079.1\|53015_53972_+	hypothetical protein	NA	NA	NA	NA
WP_155773080.1\|54258_54993_-	RES domain-containing protein	NA	NA	NA	NA
WP_065493414.1\|55188_56496_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.7e-213	84.5
WP_065493417.1\|57067_57838_-	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	1.2e-14	30.7
55155:56613	attR	NA	NA	NA	NA
WP_065493841.1\|57834_59385_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	4.0e-14	25.6
WP_081315524.1\|59784_61083_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_065491460.1\|62347_64441_-\|transposase	ISAzo13 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

462265 : 526001

Marseillevirus(20.0%)

transposase,integrase

attL 472469:472484|attR 527501:527516

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065492628.1\|462265_463522_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_065493646.1\|463621_464509_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_065493881.1\|464621_465827_+	CoA transferase	NA	NA	NA	NA
WP_065493647.1\|465888_466683_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_065493882.1\|466697_467777_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_065493648.1\|467773_468748_+	hypothetical protein	NA	NA	NA	NA
WP_065493649.1\|469026_469815_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_065493650.1\|469892_471104_+	cytochrome P450	NA	NA	NA	NA
WP_065493651.1\|471395_472844_+	APC family permease	NA	NA	NA	NA
472469:472484	attL	NA	NA	NA	NA
WP_065493652.1\|472997_474143_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_065493653.1\|474749_478001_-	protein kinase	A0A2R3ZRI5	Marseillevirus	3.4e-15	28.8
WP_065493654.1\|478903_479497_+	hypothetical protein	NA	NA	NA	NA
WP_065493655.1\|479493_480126_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_155773105.1\|480466_481168_-	hypothetical protein	NA	NA	NA	NA
WP_065493884.1\|482429_483500_+	glycohydrolase	A0A0K0N740	Gordonia_phage	2.7e-46	34.3
WP_081315586.1\|484158_484569_-	hypothetical protein	NA	NA	NA	NA
WP_065493658.1\|484594_486211_-	acyl--CoA ligase	NA	NA	NA	NA
WP_065493659.1\|486511_487141_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_081315587.1\|487337_488810_-	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	6.7e-43	32.9
WP_081315588.1\|489075_490197_+	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_081315589.1\|490202_490718_+	Zn-ribbon domain-containing OB-fold protein	NA	NA	NA	NA
WP_065493662.1\|490714_491869_+	thiolase family protein	NA	NA	NA	NA
WP_065493663.1\|491865_492435_+	hypothetical protein	NA	NA	NA	NA
WP_065493664.1\|492431_493172_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	5.6e-14	31.5
WP_065493665.1\|493168_493939_+	hypothetical protein	NA	NA	NA	NA
WP_065493666.1\|494025_495123_-	CoA transferase	NA	NA	NA	NA
WP_065493667.1\|495371_496271_+	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_065493887.1\|496438_497050_+	NIPSNAP family protein	NA	NA	NA	NA
WP_155773106.1\|497871_498063_+	hypothetical protein	NA	NA	NA	NA
WP_065493669.1\|498336_499791_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_155773107.1\|499783_499948_-	hypothetical protein	NA	NA	NA	NA
WP_065493670.1\|500497_501943_-	MFS transporter	NA	NA	NA	NA
WP_065493671.1\|505730_507125_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_065493672.1\|507212_507743_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_155773108.1\|507857_508701_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_065493673.1\|509141_509900_-	hypothetical protein	NA	NA	NA	NA
WP_065493674.1\|509912_510686_-	chlorocatechol 1,2-dioxygenase	NA	NA	NA	NA
WP_065493675.1\|510908_511820_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_081315590.1\|512196_513750_+	hypothetical protein	NA	NA	NA	NA
WP_065491073.1\|514131_515337_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_081315591.1\|515610_515955_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_081315592.1\|516011_516320_+	hypothetical protein	NA	NA	NA	NA
WP_065493679.1\|520742_521861_-	maleylacetate reductase	NA	NA	NA	NA
WP_065491533.1\|523005_524028_-\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	2.6e-06	26.9
WP_081315650.1\|525026_526001_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
527501:527516	attR	NA	NA	NA	NA

DBSCAN-SWA_3

539789 : 607699

Mycobacterium_phage(36.36%)

transposase,integrase

attL 569168:569227|attR 584247:585703

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065493889.1\|539789_541481_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_155773110.1\|541692_542950_+\|transposase	IS3 family transposase	A0A2P1JR32	Mycobacterium_phage	9.8e-136	78.2
WP_065493696.1\|544219_545290_-\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	3.6e-06	31.3
WP_065489049.1\|546071_547310_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_065493698.1\|547692_548775_-	DUF3068 domain-containing protein	NA	NA	NA	NA
WP_065493699.1\|549704_551237_-	2,4,6-trichlorophenol monooxygenase	NA	NA	NA	NA
WP_065493700.1\|551411_552242_+	hydroxyquinol 1,2-dioxygenase	NA	NA	NA	NA
WP_065489049.1\|553385_554624_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_081315595.1\|555333_556101_-	FAD synthetase family protein	NA	NA	NA	NA
WP_065493893.1\|556291_557101_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.5e-07	25.8
WP_081315596.1\|557147_558221_+	maleylacetate reductase	NA	NA	NA	NA
WP_081315597.1\|558886_559165_+	WhiB family transcriptional regulator	A0A1C9M023	Mycobacterium_phage	9.0e-10	43.0
WP_155773111.1\|559302_559833_-	hypothetical protein	NA	NA	NA	NA
WP_081315599.1\|562207_563851_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065493703.1\|564447_565011_-	flavin reductase family protein	NA	NA	NA	NA
WP_081315600.1\|565076_567995_-	transcriptional regulator	NA	NA	NA	NA
WP_081315601.1\|568213_569149_-	cupin domain-containing protein	NA	NA	NA	NA
569168:569227	attL	NA	NA	NA	NA
WP_065493414.1\|569200_570508_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.7e-213	84.5
WP_155773112.1\|570744_571635_+	NAD-binding protein	NA	NA	NA	NA
WP_081315602.1\|572194_572554_-\|transposase	transposase	NA	NA	NA	NA
WP_065493707.1\|572659_573649_-\|integrase	site-specific integrase	A0A2K9VH72	Gordonia_phage	6.5e-10	26.8
WP_065493708.1\|573645_574569_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_081315603.1\|574565_575576_-\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJ76	Virus_Rctr85	6.4e-05	37.8
WP_065493709.1\|575806_576232_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_065493710.1\|576361_576553_-	hypothetical protein	NA	NA	NA	NA
WP_081315653.1\|576612_576909_-	hypothetical protein	NA	NA	NA	NA
WP_065493711.1\|577488_578073_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_065493712.1\|578486_579803_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_065493713.1\|579802_581983_-	alpha-ketoacid dehydrogenase subunit alpha/beta	NA	NA	NA	NA
WP_065493714.1\|582201_582870_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_081315604.1\|584049_584283_-	hypothetical protein	NA	NA	NA	NA
WP_065493414.1\|584279_585587_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.7e-213	84.5
WP_065493716.1\|585626_586376_-	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase	NA	NA	NA	NA
584247:585703	attR	NA	NA	NA	NA
WP_065493717.1\|586550_587993_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_065493718.1\|588043_589420_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	7.4e-28	25.8
WP_065493719.1\|589689_590724_+	glutathione-dependent reductase	NA	NA	NA	NA
WP_065493720.1\|591976_592768_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_065489192.1\|592850_593933_-\|transposase	IS630-like element ISRjo2 family transposase	NA	NA	NA	NA
WP_081315605.1\|596691_598131_+\|transposase	transposase	NA	NA	NA	NA
WP_155773113.1\|598432_598942_-\|transposase	transposase	NA	NA	NA	NA
WP_081315606.1\|599857_600718_+	hypothetical protein	NA	NA	NA	NA
WP_065493722.1\|600796_602158_+	aminomethyl transferase family protein	NA	NA	NA	NA
WP_065493899.1\|602646_603543_+	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	1.6e-10	42.2
WP_081315607.1\|603539_604448_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	3.1e-22	30.8
WP_065493723.1\|604728_606123_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_065493672.1\|606210_606741_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_155773108.1\|606855_607699_-\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

613129 : 697940

Mycobacterium_phage(40.0%)

transposase,integrase

attL 668166:668225|attR 683245:684701

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065491073.1\|613129_614335_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_081315591.1\|614608_614953_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_081315592.1\|615009_615318_+	hypothetical protein	NA	NA	NA	NA
WP_065493679.1\|619740_620859_-	maleylacetate reductase	NA	NA	NA	NA
WP_065491533.1\|622003_623026_-\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	2.6e-06	26.9
WP_081315650.1\|624024_624999_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_065493682.1\|624995_625307_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065493683.1\|625629_626592_+	hypothetical protein	NA	NA	NA	NA
WP_065493685.1\|627546_628746_-	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_065493686.1\|629753_630329_-	YceI family protein	NA	NA	NA	NA
WP_065493687.1\|630658_631198_-	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_081315593.1\|631256_631973_+	cupin domain-containing protein	NA	NA	NA	NA
WP_065493689.1\|632578_633157_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_065493690.1\|633508_634888_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_081315651.1\|635382_636399_+	hypothetical protein	NA	NA	NA	NA
WP_081315594.1\|636527_637652_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_155773109.1\|637867_638614_-	hypothetical protein	NA	NA	NA	NA
WP_065493889.1\|638787_640479_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_155773110.1\|640690_641948_+\|transposase	IS3 family transposase	A0A2P1JR32	Mycobacterium_phage	9.8e-136	78.2
WP_065493696.1\|643217_644288_-\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	3.6e-06	31.3
WP_065489049.1\|645069_646308_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_065493698.1\|646690_647773_-	DUF3068 domain-containing protein	NA	NA	NA	NA
WP_065493699.1\|648702_650235_-	2,4,6-trichlorophenol monooxygenase	NA	NA	NA	NA
WP_065493700.1\|650409_651240_+	hydroxyquinol 1,2-dioxygenase	NA	NA	NA	NA
WP_065489049.1\|652383_653622_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_081315595.1\|654331_655099_-	FAD synthetase family protein	NA	NA	NA	NA
WP_065493893.1\|655289_656099_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.5e-07	25.8
WP_081315596.1\|656145_657219_+	maleylacetate reductase	NA	NA	NA	NA
WP_081315597.1\|657884_658163_+	WhiB family transcriptional regulator	A0A1C9M023	Mycobacterium_phage	9.0e-10	43.0
WP_155773111.1\|658300_658831_-	hypothetical protein	NA	NA	NA	NA
WP_081315599.1\|661205_662849_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065493703.1\|663445_664009_-	flavin reductase family protein	NA	NA	NA	NA
WP_081315600.1\|664074_666993_-	transcriptional regulator	NA	NA	NA	NA
WP_081315601.1\|667211_668147_-	cupin domain-containing protein	NA	NA	NA	NA
668166:668225	attL	NA	NA	NA	NA
WP_065493414.1\|668198_669506_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.7e-213	84.5
WP_155773112.1\|669742_670633_+	NAD-binding protein	NA	NA	NA	NA
WP_081315602.1\|671192_671552_-\|transposase	transposase	NA	NA	NA	NA
WP_065493707.1\|671657_672647_-\|integrase	site-specific integrase	A0A2K9VH72	Gordonia_phage	6.5e-10	26.8
WP_065493708.1\|672643_673567_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_081315603.1\|673563_674574_-\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJ76	Virus_Rctr85	6.4e-05	37.8
WP_065493709.1\|674804_675230_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_065493710.1\|675359_675551_-	hypothetical protein	NA	NA	NA	NA
WP_081315653.1\|675610_675907_-	hypothetical protein	NA	NA	NA	NA
WP_065493711.1\|676486_677071_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_065493712.1\|677484_678801_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_065493713.1\|678800_680981_-	alpha-ketoacid dehydrogenase subunit alpha/beta	NA	NA	NA	NA
WP_065493714.1\|681199_681868_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_081315604.1\|683047_683281_-	hypothetical protein	NA	NA	NA	NA
WP_065493414.1\|683277_684585_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.7e-213	84.5
WP_065493716.1\|684624_685374_-	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase	NA	NA	NA	NA
683245:684701	attR	NA	NA	NA	NA
WP_065493717.1\|685548_686991_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_065493718.1\|687041_688418_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	7.4e-28	25.8
WP_065493719.1\|688687_689722_+	glutathione-dependent reductase	NA	NA	NA	NA
WP_065493720.1\|690974_691766_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_065489192.1\|691848_692931_-\|transposase	IS630-like element ISRjo2 family transposase	NA	NA	NA	NA
WP_081315605.1\|695689_697129_+\|transposase	transposase	NA	NA	NA	NA
WP_155773113.1\|697430_697940_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

703726 : 758708

Gordonia_phage(25.0%)

transposase,integrase

attL 735920:735937|attR 759203:759220

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065493724.1\|703726_705121_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_065493900.1\|706075_706555_-	hypothetical protein	NA	NA	NA	NA
WP_081315654.1\|706963_708022_-	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_065493725.1\|708191_708434_-	hypothetical protein	NA	NA	NA	NA
WP_065493726.1\|708594_709119_-	hypothetical protein	NA	NA	NA	NA
WP_065493727.1\|709170_709818_-	hypothetical protein	NA	NA	NA	NA
WP_065493728.1\|709818_710523_-	hypothetical protein	NA	NA	NA	NA
WP_065493729.1\|710576_711110_-	hypothetical protein	NA	NA	NA	NA
WP_065493730.1\|711121_711775_-	hypothetical protein	NA	NA	NA	NA
WP_065493731.1\|711771_712224_-	hypothetical protein	NA	NA	NA	NA
WP_065493732.1\|712346_712760_-	hypothetical protein	NA	NA	NA	NA
WP_065493733.1\|713213_713999_-	multidrug ABC transporter permease	NA	NA	NA	NA
WP_065493734.1\|713995_714943_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.6e-20	30.4
WP_065493902.1\|715022_716513_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_065493735.1\|716589_717096_-	hypothetical protein	NA	NA	NA	NA
WP_065493736.1\|717162_717696_-	flavin reductase family protein	NA	NA	NA	NA
WP_065493737.1\|717692_718973_-	monooxygenase	NA	NA	NA	NA
WP_081315608.1\|719430_720444_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_081315609.1\|720701_721700_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_061043075.1\|724258_724699_-	hypothetical protein	NA	NA	NA	NA
WP_155773114.1\|724695_726861_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_081315655.1\|726860_728039_-\|integrase	tyrosine-type recombinase/integrase	S6C485	Thermus_phage	2.8e-12	27.5
WP_065493741.1\|728144_728399_-	DUF4193 domain-containing protein	NA	NA	NA	NA
WP_065493742.1\|728412_728757_-	WhiB family transcriptional regulator	A0A0R8V0E7	Thermobifida_phage	1.3e-13	44.0
WP_065493743.1\|729435_729852_-	hypothetical protein	NA	NA	NA	NA
WP_065493906.1\|730205_730817_+	5-amino-6-(5-phosphoribosylamino)uracil reductase	NA	NA	NA	NA
WP_065493744.1\|730908_731853_+	barstar family protein	NA	NA	NA	NA
WP_081315656.1\|732224_733559_+	hypothetical protein	NA	NA	NA	NA
WP_065493746.1\|733631_733931_-	hypothetical protein	NA	NA	NA	NA
WP_005567460.1\|734469_734775_-	hypothetical protein	NA	NA	NA	NA
WP_065493747.1\|734771_736685_-\|integrase	tyrosine-type recombinase/integrase	A0A1U9WS15	Gordonia_phage	1.4e-05	31.2
735920:735937	attL	NA	NA	NA	NA
WP_065493748.1\|736650_737733_-\|integrase	tyrosine-type recombinase/integrase	A0A0K1Y646	Mycobacterium_phage	1.5e-07	30.4
WP_054246999.1\|739299_740070_+	AAA family ATPase	NA	NA	NA	NA
WP_065493907.1\|740762_741467_+	SOS response-associated peptidase	A0A1P8CX02	Bacillus_phage	2.3e-25	41.5
WP_065493751.1\|741552_741774_+	hypothetical protein	NA	NA	NA	NA
WP_065493752.1\|741939_743247_+	CopG family transcriptional regulator	NA	NA	NA	NA
WP_065493753.1\|743294_743627_+	hypothetical protein	NA	NA	NA	NA
WP_065493754.1\|743770_744118_+	Lsr2 family protein	A0A160DEV0	Gordonia_phage	1.9e-17	45.7
WP_065493755.1\|744227_744464_+	hypothetical protein	NA	NA	NA	NA
WP_065493756.1\|745005_745299_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_065493757.1\|745327_745573_+	hypothetical protein	NA	NA	NA	NA
WP_155773115.1\|745618_746146_-	hypothetical protein	NA	NA	NA	NA
WP_065493908.1\|747456_747882_-	hypothetical protein	NA	NA	NA	NA
WP_065493758.1\|748828_749329_-	N-formylglutamate amidohydrolase	NA	NA	NA	NA
WP_065493759.1\|749493_750312_-	SDR family oxidoreductase	F2NZ12	Diadromus_pulchellus_ascovirus	1.1e-05	30.2
WP_065493760.1\|750355_751207_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_065493761.1\|751235_752237_-	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_065493762.1\|752233_753148_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_065493763.1\|753282_753858_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_081315610.1\|753919_754300_+	DUF4345 domain-containing protein	NA	NA	NA	NA
WP_081315658.1\|754332_754980_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_155773133.1\|755538_755997_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_065493765.1\|756000_757122_+	AAA family ATPase	NA	NA	NA	NA
WP_081315611.1\|757571_758708_+\|integrase	site-specific integrase	NA	NA	NA	NA
759203:759220	attR	NA	NA	NA	NA

DBSCAN-SWA_6

783548 : 841424

Burkholderia_virus(11.11%)

transposase,integrase

attL 783497:783556|attR 857860:859216

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
783497:783556	attL	NA	NA	NA	NA
WP_155773092.1\|783548_784821_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	3.7e-58	52.9
WP_065493911.1\|788469_789165_-	chlorite dismutase family protein	NA	NA	NA	NA
WP_065493780.1\|789281_789734_-	hypothetical protein	NA	NA	NA	NA
WP_065493781.1\|789824_790238_-	hypothetical protein	NA	NA	NA	NA
WP_065493782.1\|790513_791563_-	hypothetical protein	NA	NA	NA	NA
WP_065493783.1\|791843_792149_-	EthD family reductase	NA	NA	NA	NA
WP_065493784.1\|792183_793044_-	catechol 1,2-dioxygenase	NA	NA	NA	NA
WP_065493785.1\|793183_794506_-	cytochrome P450	NA	NA	NA	NA
WP_065493786.1\|794579_795551_-	oxidoreductase	NA	NA	NA	NA
WP_065493787.1\|795969_796908_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_065493788.1\|797083_798109_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_081315619.1\|801021_801309_-	WhiB family transcriptional regulator	A0A097EWF7	Mycobacterium_phage	1.8e-05	41.4
WP_065493790.1\|801395_802571_-	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_065493791.1\|802737_803040_-	EthD family reductase	NA	NA	NA	NA
WP_155773121.1\|804776_805778_+\|transposase	transposase	A0A1B3AZF8	Gordonia_phage	3.4e-14	50.0
WP_155773122.1\|806309_806705_+\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	2.9e-17	45.5
WP_065493792.1\|806990_807401_+	helix-turn-helix domain-containing protein	K4ICM4	Acidithiobacillus_phage	5.8e-13	38.6
WP_081315622.1\|807536_808064_+	hypothetical protein	NA	NA	NA	NA
WP_081315623.1\|808954_809545_-	zinc-ribbon domain-containing protein	NA	NA	NA	NA
WP_081315624.1\|809545_810868_-	hypothetical protein	A0A1B1P7Q7	Bacillus_phage	6.0e-11	27.4
WP_081315625.1\|810672_811227_-	zinc-ribbon domain-containing protein	NA	NA	NA	NA
WP_065493794.1\|811441_814198_-	hypothetical protein	A0A1V0SJ58	Klosneuvirus	3.9e-20	20.2
WP_065493912.1\|814756_815338_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_155773123.1\|815584_815971_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_065493795.1\|815852_816338_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_155773134.1\|816454_817840_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_065493797.1\|818060_819749_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_065493798.1\|819878_820418_-	TIGR00730 family Rossman fold protein	NA	NA	NA	NA
WP_065493799.1\|821736_824478_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065493802.1\|825935_826970_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_081315627.1\|827373_828303_-	FHA domain-containing protein	NA	NA	NA	NA
WP_065493805.1\|828289_828970_-	glycosyltransferase	NA	NA	NA	NA
WP_065493806.1\|829035_829674_-	HD domain-containing protein	NA	NA	NA	NA
WP_065493807.1\|829903_830848_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_065493808.1\|834662_835652_-\|integrase	site-specific integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	6.5e-10	32.5
WP_155773135.1\|835973_837200_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_065493810.1\|837196_838132_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_065493811.1\|838128_839169_+\|integrase	tyrosine-type recombinase/integrase	Q83VS6	Escherichia_phage	1.0e-05	25.6
WP_065493812.1\|839229_840135_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_155773124.1\|840131_841424_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
857860:859216	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP009111

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009111_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009111_1

38081-38162

Orphan

Consensus_repeat	Method
CGTAGGCCTGCTGGCCGTAACCGCCCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009111_1

>merge|NZ_CP009111|1|38081-38162|CRISPRCasFinder
CGTAGGCCTGCTGGCCGTAACCGCCCTGGTCGTAGTCGGCGTAGCCCTGCTGGTCGTAGGCCTGCTGGTCGTAACCGCCCTG

>NZ_CP009111|1|1|38081-38162|CRISPRCasFinder
CGTAGGCCTGCTGGCCGTAACCGCCCTG	GTCGTAGTCGGCGTAGCCCTGCTGGT
CGTAGGCCTGCTGGTCGTAACCGCCCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009111.1\|WP_065488350.1\|31265_32651_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP009111.1\|WP_005263438.1\|39704_40100_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009111.1\|WP_065488362.1\|45011_46295_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_CP009111.1\|WP_007301411.1\|27879_28581_+\|DUF881-domain-containing-protein	unknown	unknown	gnl\|CDD\|377575
NZ_CP009111.1\|WP_005263432.1\|43761_44208_-\|mitomycin-C-resistance-protein	unknown	unknown	gnl\|CDD\|319901
NZ_CP009111.1\|WP_155772950.1\|46352_46862_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009111.1\|WP_005263451.1\|28635_29289_+\|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl\|CDD\|181107
NZ_CP009111.1\|WP_005565380.1\|40804_41266_+\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NZ_CP009111.1\|WP_065488348.1\|29349_31269_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP009111.1\|WP_005263442.1\|35591_37061_-\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704
NZ_CP009111.1\|WP_005249076.1\|34137_35592_-\|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl\|CDD\|223843
NZ_CP009111.1\|WP_065488354.1\|40154_40808_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009111.1\|WP_081315242.1\|26970_27429_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|371225
NZ_CP009111.1\|WP_065488359.1\|43088_43772_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378964
NZ_CP009111.1\|WP_065488357.1\|41282_42854_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_CP009111.1\|WP_005263445.1\|32653_34141_-\|penicillin-binding-protein-2	unknown	unknown	gnl\|CDD\|223839
NZ_CP009111.1\|WP_081315243.1\|44256_44664_+\|polyketide-cyclase	unknown	unknown	gnl\|CDD\|176874
NZ_CP009111.1\|WP_005249074.1\|37057_37522_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224630
NZ_CP009111.1\|WP_005263426.1\|48014_48392_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009111.1\|WP_005249082.1\|27496_27760_-\|cell-division-protein-CrgA	unknown	unknown	gnl\|CDD\|178907

Protein	Function_ID	Function_description	E-value
NZ_CP009111.1\|WP_065488350.1\|31265_32651_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.60211e-120
NZ_CP009111.1\|WP_065488359.1\|43088_43772_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	1.62215e-12
NZ_CP009111.1\|WP_065488362.1\|45011_46295_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	9.75345e-136
NZ_CP009111.1\|WP_007301411.1\|27879_28581_+\|DUF881-domain-containing-protein	gnl\|CDD\|377575	pfam05949, DUF881, Bacterial protein of unknown function (DUF881). This family consists of a series of hypothetical bacterial proteins. One of the family members YlxW from Bacillus subtilis is thought to be involved in cell division and sporulation.	6.15264e-53
NZ_CP009111.1\|WP_005263451.1\|28635_29289_+\|aminodeoxychorismate/anthranilate-synthase-component-II	gnl\|CDD\|181107	PRK07765, PRK07765, aminodeoxychorismate/anthranilate synthase component II.	1.21575e-149
NZ_CP009111.1\|WP_005565380.1\|40804_41266_+\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	4.8043e-15
NZ_CP009111.1\|WP_065488348.1\|29349_31269_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.01126e-127
NZ_CP009111.1\|WP_005263442.1\|35591_37061_-\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.75827e-80
NZ_CP009111.1\|WP_005249076.1\|34137_35592_-\|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl\|CDD\|223843	COG0772, FtsW, Bacterial cell division membrane protein [Cell division and chromosome partitioning].	1.04166e-88
NZ_CP009111.1\|WP_081315242.1\|26970_27429_-\|PH-domain-containing-protein	gnl\|CDD\|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	7.86146e-05
NZ_CP009111.1\|WP_005263432.1\|43761_44208_-\|mitomycin-C-resistance-protein	gnl\|CDD\|319901	cd07235, MRD, Mitomycin C resistance protein (MRD). Mitomycin C (MC) is a naturally occurring antibiotic, and antitumor agent used in the treatment of cancer. Its antitumor activity is exerted primarily through monofunctional and bifunctional alkylation of DNA. MRD binds to MC and functions as a component of the MC exporting system. MC is bound to MRD by a stacking interaction between a His and a Trp. MRD adopts a structural fold similar to bleomycin resistance protein, glyoxalase I, and extradiol dioxygenases; and it has binding sites at an identical location to binding sites in these evolutionarily related enzymes.	6.86297e-58
NZ_CP009111.1\|WP_065488357.1\|41282_42854_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.10856e-16
NZ_CP009111.1\|WP_005263445.1\|32653_34141_-\|penicillin-binding-protein-2	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	6.97822e-94
NZ_CP009111.1\|WP_081315243.1\|44256_44664_+\|polyketide-cyclase	gnl\|CDD\|176874	cd08865, SRPBCC_10, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	0.000201285
NZ_CP009111.1\|WP_005249074.1\|37057_37522_-\|FHA-domain-containing-protein	gnl\|CDD\|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	6.50815e-24
NZ_CP009111.1\|WP_005249082.1\|27496_27760_-\|cell-division-protein-CrgA	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	9.93822e-50

>NZ_CP009111.1|WP_005249074.1|37057_37522_-|FHA-domain-containing-protein
MQGLILQLTRAGFLLLLWLFVWTVLRALRGDIYAGSGVRVPPRYSRSGNVLPSLGKTKTAKYLVVTQGGLAGTRITLGTQPVLIGRADDSTLVLTDDYASTRHARLSPRGADWYVEDLGSTNGTYLDRAKVTTSVRVPLGTPVRVGKTVIELRP
>NZ_CP009111.1|WP_005263442.1|35591_37061_-|serine/threonine-protein-phosphatase
MTLVLRYAARSDRGLVRSNNEDSVYAGARLLALADGMGGHAAGEVASQLMIAALAHLDDDEPGEDLLGKLEAATREGNDSIADHVEEDPELDGMGTTLTAILFSGNKLGLVHIGDSRAYLLRDDSLAQITRDDTFVQSLVDEGRITAEQAHTHPQRSLIMRALTGNEIEPTLTVREARAGDRYLLCSDGLSDVVSDETIENTMREGSQDECADRLIELALRSGGPDNVTVVVADVIDLDYGQSHPIVAGAASADDEEDTPPPNTAAGRAAAMRPPRATPKRVVPQVEEPPTKKKRHRMWWAALALGLIVVVAVAAFVGRALVRNNYYVGADGERVTVLRGVPGSVLGYSLQEANLVGCVSDAGDLTLMSPTESPNGCTILEVDDLQPSAREQVRAGLPSGKLDDVRNQMTRLAQNDLLPVCESESSTTTTTTPAPTPAPVPETTPPPAPAPVPPAEVPPGPGPTAPPTPTATPAPTVTQVPGQNCRTAS
>NZ_CP009111.1|WP_005249076.1|34137_35592_-|FtsW/RodA/SpoVE-family-cell-cycle-protein
MSVASASPGAQFPSPPGGFAPAPVQSTRRGTELILIGFAILITTISLVLVEASQEQSITWDLAKYAAAYSALFLIAHLAVRRFAPYADPLILPIVALLNGLGLVLIHRLDLADAQSAAYFGLPVPSPDANQQVLWTTLAIAGFVAVLVLLKDYRLLARYSYTLGLAGLVFLAIPAILPSSFSEVNGAKIWIRLPGFSIQPGEFAKILLIIFFASVLVAKRDLFTTAGKHVFGIDLPRARDLGPILLAWMVSVGVLVLEKDLGTSLLLFSTVLVMLYIATERVGWLLIGAGLLGIGFFFAYQLFGHVRVRVSTWLDPLADYNNTGYQISQSLFGLATGGVAGTGLGSGRPAQVPFAKTDFIVATIGEELGLIGLAAVLMLFLILVIRGLRTALAVRDSFGKLLAAGLSFTIAVQVFVVVGGVTKLIPLTGLTTPFMSYGGSSLLANYLLLAILIKISDAAREPAVPKKKGPAPIADAPTEMVPRS
>NZ_CP009111.1|WP_005263445.1|32653_34141_-|penicillin-binding-protein-2
MNTPLRRVAIAVMVMVVALLANATYVQVIKADNLRADPRNSRVLLDEYSRQRGQISAAGQVLAASVPTDDRYKYLRTYPPNPAAPSSPLANAPVTGFYSMQYGSTGLERTEDPVLNGSDNRLFGRRFFDLVSGRDPRGGNVVTTINPVMQQVAYDELTAKGYTGSVVAIEPSTGRILTMVSTPSYDPNSLASHDGTETTAAWEALNADPEKPLINRAVSQTYPPGSTFKVVVTAAALAAGTTPDTQLTAAPQITLPGTSTTLENYNGSTCGGAPTASLREAFARSCNTAFVELGVKTGTDAVSDQSSALGIGGQMPGVPFPVADSTIGSIPDDAALGQSSIGQRDVALTPLQNAMIAATVANGGVRMQPQLVSELQGPDLSNLATTNPVSEGQAMSSQVAATLTDLMIGSENNTSGEGKIPGVQIASKTGTAEHGTDPRNTPPHAWYIGFAPAQNPTVAIAVIVEDGGDRALAATGGSVAAPIGRAVIAAGLQGG
>NZ_CP009111.1|WP_065488350.1|31265_32651_-|serine/threonine-protein-kinase
MALNNGALIANRYRLIRLIATGGMGQVWEATDNRLNRRVAVKVLKSEFSSDPEFVERFRFEARTTAQLNHSGIAGIYDYGEVRDATGDSTAYLVMELVNGEPLNAVLARVGRLAVPHALDMLEQTGRALQVAHDAGVVHRDVKPGNILITPTGQVKITDFGIAKAVENSPVTRTGMVMGTAQYIAPEQALGQDATAASDVYSLGIVGYEALSGRRPFVGDGAITVAMKHVQEAPAPLPSDLPPNIRELIDITIAKDPSTRYASGGEFADAVAAVRAGRRPPPPGTSGTGAARVLPPPMTGATQMMPPSQTAYAGPVTGQVPPDDSNGDGKKGGLTSGQKAVAWGAGGLLVLAAIIALALVLFDGGDTKEPTSPAITSSLQTITTTPRPTTTTEPPYTTTTTEPPYTTTTTQPFTTTTTQPTTTTTTEPTTTTTTTTTTAPTTTTTTTTSEESTTPTPQGLP
>NZ_CP009111.1|WP_065488348.1|29349_31269_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTTPRNLSSRYELGEILGFGGMSEVHLARDVRLSRDVAIKVLRADLARDPTFYLRFRREAQNAAALNHPAIVAVYDTGEAETDAGPLPYIVMEYVDGDTLRDIVRSEGPMASRRAMEVISDVCAALDFSHRNGIVHRDVKPANVMINRAGAVKVMDFGIARAISDASSPMTQTAAVIGTAQYLSPEQARGEQVDARSDVYSLGCVLFEILTGEPPFKGDSPVAVAYQHVREDPQTPSVVNPDIPRELDSVILKAMSKNPANRYQTAADMRSDLVRVLGGQRPSAPMVMSDEDRTTILGAVDSGAGNYRRPQSPTPATASKTDGGEPDKKKNPMRVALMALGALIVVGIVGAFLWSVGPGSKADQVTMPDVTNQAADDAETTLQNLGFRVARQQKPDAVVATGNVITTRPVGGVQVDEGSTITLEVSSGPEQVKVPRLAGLTQQEAQQELNAVGLRLDTAVARAPSDVSDVDKVIEQNPSSGASISLDSEVAVTLGTGPEQIRIPDVTGQKVEVAQANIEGAGFKVQIQNIDSGVPKGQVVSTDPVGGSTAAKGDTIQIRVSNGNNIEMPDLTGKTVSQALAELRSAGWSGSSSSINQTQTSTLDPEMVGKIISQEQPPGSEITKNGVVSVGVGALGIPR
>NZ_CP009111.1|WP_005263451.1|28635_29289_+|aminodeoxychorismate/anthranilate-synthase-component-II
MRILVVDNYDSFVFNLVQYLGQLGTRAVVWRNDDPNLTGPDAVAAAAAEFDGILLSPGPGTPQRAGATMDLVTACAAAETPLLGVCLGHQAIGAAFGATVDRAPELLHGKTSVVHHTGEGVLAGLPDPFTATRYHSLTVLEDTIPDELEVTAHTDSGIVMAMRHRELPIHGVQFHPESVLTEGGHRMLANWLTVCGEAPKESLVATLETEVAQALGA
>NZ_CP009111.1|WP_007301411.1|27879_28581_+|DUF881-domain-containing-protein
MTRSIFWRIAVLVVCLVAGLLVATTRQVSHGNEIRAGDSTRLSDLVRNAQSETDQVAETRDRLAAQVESLQQDAAASDSGVAQALADTKALATDAGLTPMTGPGVTVTLTDAPRDADGKYPVDASPDDLVVHQQDVQSVLNALWVGGAEAISMQDQRIVNTSAPRCIGNTLLLHGRTYSPPYVMSAIGDPTRLEAALANEPGIRVFKQYASRFGLGYSEAASGQLTVPGYAGH
>NZ_CP009111.1|WP_005249082.1|27496_27760_-|cell-division-protein-CrgA
MPKSKVRKKTDYTINPASRTPVKVKAGPSSTLYVSVMLGFMLVGLVWLLVYYLAADQLEWMNNLGAYNFLIGFGFMVVGLIMTMRWR
>NZ_CP009111.1|WP_081315242.1|26970_27429_-|PH-domain-containing-protein
MLMSADEAPLEWSTPLGAVIALAAGGVALGVAGLAVSTEPAGRVLVCVAALGLLLTAASALRQRPRLAVDKEGGGIVVNRLRGRHRYARSEIERARLVRYPRLGRRVPMLEIDIRTEDGTERLLIFGRWDLGTNPEDVFDALAVHRLVGRGQ
>NZ_CP009111.1|WP_005263438.1|39704_40100_+|hypothetical-protein
MSISQVRATSSANVGEYVGSVATTVGALSVDWWCTPAFDAVVTLSCEIPYYRGRKAVLAWNRHFGWSLGVHGLTQGNVLVVEGLGLGPAPDPAHCSDRVAELIAELADWAPRPASGQPAPRIVHGPGAPRG
>NZ_CP009111.1|WP_065488354.1|40154_40808_+|hypothetical-protein
MDGRKAPDPLRLAAGVAATAGGAMQRVIGFGVDTARLLPGVDPLLVTLEERGTQTLRSADELADRLLHAVLRRIVHVALQEVDLTAIVHDHVDLDVVAEGIDIQRIIDRVDIDAIAARVDIPQILDRVDIDAVAARIDVDAIVDRVDVDSVIGRVDLVVLADTVIEGVDLPRIIRESTDSMSNEAVRGVRTQGMQADDAVAGFVGKWFGRGHEPDDA
>NZ_CP009111.1|WP_005565380.1|40804_41266_+|RDD-family-protein
MSTPAHRAAGIVTRGLAAGIDLAVVLAMMGGIYVGVLFLRLLFSPQEFSFPDANAVLSATLFIGVAVLYLTACWSVSGRTVGAVTMGLRVVSRNGELIGWLRALLRAVLCVMFGFGLLWAAVDGRRRSLQDILLRTAVIYDWEPDLHVGEPEI
>NZ_CP009111.1|WP_065488357.1|41282_42854_-|IS1634-family-transposase
MAAYIRKVRTASGATAVQIAAKQGRRDKVLEHLGSAHTDSELAALLETAREKLLAGQQQLDLDLGTNTGGSATINGKRSRWLIEVIETAWRHLGFDVVDNEAFFQLVAARIVEATSVADAGRVLGEIGIAPAHRNTFVRTLRRCTAHGYRDDIARRCFEHAAEASDLNLLLYDVTTLYFEAEKEDELRKVGYSKERRVDPQIVVGLLVDRNGFPLEIGCFEGNHAETRTIVPIVRQFQERHNIEDVEMVIAADAGMLSASNLKDLDAAGLKFIVGSRVMKAPADLASHFHWNGDVFTDGQVIDTVTPRHAKSVVNDITRRSEPVWDPADTSAWRAIWAYSKKRAVRDNQTLNAQEARAREVIDGTRAARSPRFVKTTAKGKSLDAEGIARARSLVGLKGYVTNLPVSLMNPYEVIEKYHDLWQVEQSFRMSKTDLRARPIFSHTRDSIEAHLTIVFAALAISRYLQAETGMSIRRIVRSLRPLQEITVTIAGHAHTALDPLTDDAASILDSLEIPNPRSGLAH
>NZ_CP009111.1|WP_065488359.1|43088_43772_+|AraC-family-transcriptional-regulator
MYTERRSVYPGVVVWQKTAAGGEAAILPDGCMDLIWMNGDVVVAGPDSRPYLTRSCDGDRYVGLRCSPGTLPDLLGTPAEELTNLRVPLAEVLTDRATTEFLGRIADDADPGRALEEFARSRRLLGPPPDGRIPAIARLLEQQTSVREVADRIGVGERQLHRLCRRQFGYGPKMLARILRLQSALGLAGSSIPAAQAAGMAGFADQAHLIREAHELTGRTFGQLVTV
>NZ_CP009111.1|WP_005263432.1|43761_44208_-|mitomycin-C-resistance-protein
MSETFNAGPPEIVSVLGMTATFSAIELVVHDLPASLAFYRRLGLDIPADADQAPHVEFEFPGGVRLLWDTVETIRSFTPDWTEPAGGHRIGLAFDCGTAADVDTLFDEFTGGGYTGRKKPWDAPWGQRYATVDDPDGNPVDLFAALTP
>NZ_CP009111.1|WP_081315243.1|44256_44664_+|polyketide-cyclase
MLGAMTTESTHVSVFIARTAADVYAYASDPANLPAWAAGLSTNITRDGDRWLADSPMGQVAVTFAPANDYGILDHEVTLPSGDTVYNPVRVIPDGDHSEVVFTIRRRDGVTAEEFAEDAAAVNADLQRLKGLLEA
>NZ_CP009111.1|WP_065488362.1|45011_46295_+|IS256-family-transposase
MTDVIDLEAESNSARVGVSDARLQELVDQARADGLQLTGEGGLLAKLTKLVVESALEGEMDDHLGYGKNDSVGRGSGNSRNGRRAKTVLTEAGPVELEVPRDRESSFEPKIVAKRQRRLTGVEDMVISLSAKGLTTGEISAHMAEVYGAEVSKQTISTITERVMDGMLEWQNRPLDQVYPVLFIDCIHVKIRDGNVANRPIYVVMGVTADGTRDILGLWAGEHGDGEGAKYWLRVLSELKNRGVQDVLIVVCDGLKHLPDSIGQVWPQTIVQTCVVHLLRNTYAYASRKDWAEIAKDLKPVYTAPSEQAALDRFAEFSDKWEKRYPAIIRMWTNAWAEFVPFLQFDHAIRQVIYTTNAIESVNARIRRAVKARGHFPTEAAALKCVYLAIMSLDPKGTARQRWSNRWKAALNAFEITFDGRLSAGRK
>NZ_CP009111.1|WP_155772950.1|46352_46862_-|hypothetical-protein
MATVESIVHSALHQSPIGSTDWDPLRIEDLLQECALLDVRHFTSSSIIGILLDLRTALQLDIGNTALVVIGGVSGYSWVSDTVEADTMMRTVVGSYPTMSATEYKLELACSPRSAFQVKGKWASFFEGTVRSIGESQPDLTSVDPTTLASGFPNWQSELAIAYGTTARV
>NZ_CP009111.1|WP_005263426.1|48014_48392_-|hypothetical-protein
MGESVGDCSALLAEMDAFRQGFGQPALLTDALRSALLLIPLTGDDRLLTSTFGGLNWVCAFTSKQEYARYLLARDEQGGPCRFHTVFGWRLLDILVPSVPGPTGVVIDVAGATPMAFPPAVEEVA

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Crispr_ID: NZ_CP009111_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009111_2

461825-462042

Orphan

Consensus_repeat	Method
GGCGGGTAATTTCCGCCGGGCGGCGG	CRT

3 spacers

The CRISPR arrays of NZ_CP009111_2

>merge|NZ_CP009111|2|461825-462042|CRT
GGCGGCGGATATCCGCCGGGCGGCGGTCCCTGCGGCGGCGGCGGGTAATTGCCCTGCGGCGGCGGGTAATTTCCGCCGGGCGGCGGCGGTGGGTAATTACCGGGCGGTGGATAGTTTCCGCCGGGCGGAGGCGGGTAGTTTCCGCCGGGCGGCGGTGGCGGATATCCGCCGGGCGGCGGTCCCTGCGGCGGCGGAGGGTAATTCCCCGGGGGCGGCGG

>NZ_CP009111|2|1|461825-462042|CRT
GGCGGCGGATATCCGCCGGGCGGCGG	TCCCTGCGGCGGCGGCGGGTAATTGCCCTGCGGC
GGCGGGTAATTTCCGCCGGGCGGCGG	CGGTGGGTAATTACCGGGCGGTGGATAGTTTCCGCCGGGCGGA
GGCGGGTAGTTTCCGCCGGGCGGCGG	TGGCGGATATCCGCCGGGCGGCGGTCCCTGCGGCGGC
GGAGGGTAATTCCCCGGGGGCGGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009111.1\|WP_065488722.1\|456236_458120_-\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|293759
NZ_CP009111.1\|WP_005253325.1\|448090_448693_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP009111.1\|WP_005248717.1\|459513_460242_-\|queuosine-precursor-transporter	unknown	unknown	gnl\|CDD\|376842
NZ_CP009111.1\|WP_065488723.1\|458226_459471_+\|tRNA-guanosine(34)-transglycosylase-Tgt	unknown	unknown	gnl\|CDD\|234642
NZ_CP009111.1\|WP_005253353.1\|469991_470672_-\|DUF1275-domain-containing-protein	unknown	unknown	gnl\|CDD\|226146
NZ_CP009111.1\|WP_005253351.1\|468536_469346_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378964
NZ_CP009111.1\|WP_065488726.1\|465109_465778_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251
NZ_CP009111.1\|WP_037202832.1\|465831_466413_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP009111.1\|WP_065488727.1\|466402_467941_-\|metallophosphatase	unknown	unknown	gnl\|CDD\|277344
NZ_CP009111.1\|WP_065488717.1\|448743_451092_+\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|225272
NZ_CP009111.1\|WP_005253343.1\|462883_463840_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP009111.1\|WP_065488718.1\|451237_452971_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP009111.1\|WP_065488719.1\|452967_454947_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP009111.1\|WP_005253341.1\|461148_461817_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227760
NZ_CP009111.1\|WP_065488721.1\|454989_456231_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009111.1\|WP_005253350.1\|467979_468540_-\|TIGR03086-family-protein	unknown	unknown	gnl\|CDD\|274424
NZ_CP009111.1\|WP_005572850.1\|462345_462915_+\|DUF4190-domain-containing-protein	unknown	unknown	gnl\|CDD\|379388
NZ_CP009111.1\|WP_005253352.1\|469501_470017_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226765
NZ_CP009111.1\|WP_005253344.1\|463851_464463_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379409
NZ_CP009111.1\|WP_065488725.1\|460360_460990_-\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640

Protein	Function_ID	Function_description	E-value
NZ_CP009111.1\|WP_065488722.1\|456236_458120_-\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|293759	cd16035, sulfatase_like, uncharacterized sulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	2.8827e-41
NZ_CP009111.1\|WP_005253325.1\|448090_448693_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	3.46236e-22
NZ_CP009111.1\|WP_005248717.1\|459513_460242_-\|queuosine-precursor-transporter	gnl\|CDD\|376842	pfam02592, Vut_1, Putative vitamin uptake transporter.	2.45077e-50
NZ_CP009111.1\|WP_065488723.1\|458226_459471_+\|tRNA-guanosine(34)-transglycosylase-Tgt	gnl\|CDD\|234642	PRK00112, tgt, queuine tRNA-ribosyltransferase; Provisional.	1.98365e-171
NZ_CP009111.1\|WP_005253353.1\|469991_470672_-\|DUF1275-domain-containing-protein	gnl\|CDD\|226146	COG3619, COG3619, Predicted membrane protein [Function unknown].	2.31633e-34
NZ_CP009111.1\|WP_005253351.1\|468536_469346_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	1.93563e-14
NZ_CP009111.1\|WP_065488726.1\|465109_465778_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	1.30701e-51
NZ_CP009111.1\|WP_065488727.1\|466402_467941_-\|metallophosphatase	gnl\|CDD\|277344	cd07399, MPP_YvnB, Bacillus subtilis YvnB and related proteins, metallophosphatase domain. YvnB (BSU35040) is an uncharacterized Bacillus subtilis protein with a metallophosphatase domain. This family includes bacterial and eukaryotic proteins similar to YvnB. YvnB belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	7.5851e-24
NZ_CP009111.1\|WP_065488717.1\|448743_451092_+\|MMPL-family-transporter	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	7.17586e-113
NZ_CP009111.1\|WP_005572850.1\|462345_462915_+\|DUF4190-domain-containing-protein	gnl\|CDD\|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	1.50304e-20
NZ_CP009111.1\|WP_065488718.1\|451237_452971_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.84472e-156
NZ_CP009111.1\|WP_065488719.1\|452967_454947_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP009111.1\|WP_005253341.1\|461148_461817_-\|hypothetical-protein	gnl\|CDD\|227760	COG5473, COG5473, Predicted integral membrane protein [Function unknown].	5.31528e-12
NZ_CP009111.1\|WP_037202832.1\|465831_466413_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.56852e-08
NZ_CP009111.1\|WP_005253350.1\|467979_468540_-\|TIGR03086-family-protein	gnl\|CDD\|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	2.43405e-27
NZ_CP009111.1\|WP_005253343.1\|462883_463840_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	2.48463e-127
NZ_CP009111.1\|WP_005253352.1\|469501_470017_+\|hypothetical-protein	gnl\|CDD\|226765	COG4315, COG4315, Uncharacterized protein conserved in bacteria [Function unknown].	7.35906e-14
NZ_CP009111.1\|WP_005253344.1\|463851_464463_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|379409	pfam13977, TetR_C_6, BetI-type transcriptional repressor, C-terminal. This family comprises the C-terminal portion of proteins that belong to the TetR family of transcriptional regulators. The C-terminus represents the regulatory region, and does not include the DNA binding helix-turn-helix domain. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. One of the target proteins is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	6.18302e-11
NZ_CP009111.1\|WP_065488725.1\|460360_460990_-\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	4.13129e-18

>NZ_CP009111.1|WP_005253341.1|461148_461817_-|hypothetical-protein
MSDYGTPGQTPGQFSVGDAIGYGWNKFKDNALIWIGILLIAAIIQVVLNLVFGGFSTSSDMSAAFSVWRIIGTIVTTIVGYLINAALVRGALHEVDGNKPAFGSFFQFTNVGAIIIASVIIGVAATIGFVLLIIPGLIVIFLTWWTLQFVIDQNEDAITGIKSSFRVISQNVGPVLLLALALVGINIVGAILCGVGLLVSIPITIIASTYAYRVLTGRYVAA
>NZ_CP009111.1|WP_065488725.1|460360_460990_-|RDD-family-protein
MTTGGFDPGQGQQPFGGQQYGQPHYNGAGQHGQQFGAPPQFDSAQQFGTQPFAQPDFGFDPSRPGELLPRLGARVIDGLIVGIPMAVVSTVLALVLGNFVGSVLGAILTAAAAVGYFVFLETTRGQTLGKQILGLRVEGPNGGLPTQQQSLTRNGFYVLSALGGFPLLGFLFGLLGVVAAIVIGVTINGSPTKQGKHDELAGGTRVVQG
>NZ_CP009111.1|WP_005248717.1|459513_460242_-|queuosine-precursor-transporter
MTASDQQTKPDDHATFAHVSRGYYPTFVALFTATLLISNICATKGVAFFADSSLTIGPLQILPVITDGGFFLFPLAYILGDVLSEVYGFKSTRRAIYLGFGALILAAFCFWLLIELPSADFYENQEALRSVVGVYPRLLLAGLAGYLVGQMLNSVTLVLIKERTKEKHLWARLIGSTIVGEFADTLIFCSIAAGAIGISTWSDFVNYVIVGFLWKTLVEVLVMPITYRVIAYVKKREPTYQL
>NZ_CP009111.1|WP_065488723.1|458226_459471_+|tRNA-guanosine(34)-transglycosylase-Tgt
MNAVVPTPPDPFFTVGTRLDGQLGRTGTIHTPHGDIATPSFVAVGTKATVKAVLPESMKELGAQSLLANAYHLYLQPGPDIVDEAGGLGKFMNWDGPTFTDSGGFQVMSLGVGFKKVLAMEAVGVRSDDVIAKGKERLATVDDDGVTFKSHLDGSRHRFTPEVSMQIQHQLGADIMFAFDELTTLLNTRGYQEQSVERTQAWAVRCIAEHEKLTAERSHRPYQALFGVVQGAQYEDLRRQACRGLESITGESGRGFDGYGIGGALEKQNLGTIVRWCNEELPEHKPRHMLGISEPDDFFVAIENGADTFDCVNPSRVARNAAIYHPDGRFNINTSRFRRDFTPIDENCDCYTCANYTSAYIHHLFKAKEMLASTLCTIHNERFTVRLVDQIRASIEGGYFDEFKADTLGRFYRT
>NZ_CP009111.1|WP_065488722.1|456236_458120_-|sulfatase-like-hydrolase/transferase
MSDEKAGHRIDRRTFLSGAAVAGGVTVMSGLFDRRADASEKPLHRQPSNYVQPNIVFIVVDEMRFPQVFPAGITTADQFLQRFMPNLYTLWAPGVKFTQHYTAGVACSPGRACFVTGLYPLQNWMLQTRTGNRASPVPSPAMGRDFPTYGKLLRQAGYVTPYVGKWHLSPSPDEDSGLAPGYLEEYGFDGLTMPDIIGMNGEGFEFDGHIADQAAAWLSTRKPGDGPFCLTASFVNPHDQQFFWAGTEAERYQSLYANNVPPLSPARAWSVTTAESDPPRLGYPSVPPNWEPEKALQSKPSTQVFAREFQALVWGGVTDDIQNLSNYYLQPYGQGTDPDRHIAFAPYTYWERALDSYTNVLSMVDHHIGTVINSLPEDVAANTVFVMTSDHGEYAGAHGFVAGKLSTAYDEAFHIPLIVADPTGRFTGDTDTPRGQLTSSVDVVPLLATLGHGDRNWMSGDLFATYAERVDLLPLLRSNAAAGRDHVVLATNEHAPQGVNWNNSPTHIYVLRTPEAKVAVYSKWLGPTAYIDPASFQYEFYDYATERGRAELDNTFDHDPRGPAMAAQLMTQYLPTQLAAPLPPAFAQQGADAMARYLAYIQLINRYTPGEIDREGIDKLTAFGEVF
>NZ_CP009111.1|WP_065488721.1|454989_456231_-|hypothetical-protein
MTGKVVAAVLVLLLWSGGTSLASAAPPPTAQCAWQFMSDSTVLDVAFPDANATYWVLPYALGPGDTIELSGTYPAARYFSLNTYGTNFDTVDTLRDNQIGPDPGSGNPFADAAADALPATQKRWHATVVTGPADHSRNQIQALPAGADAQSVPVGFLIIRVYVPDDPASPTGGVPLPDVTLTFGGRTSPVPTCGSAFDPSAYDNGPLGQAAEAAFDQIIAGAASGAFPGNVPEATFVNPASTSGLFPNGDNKYVGAGLTYQPGRIVVVQGRAPTFPDTRAGQPVTAPGRQVRYWSMCQNDQVTPYPVVACAADFQTRTDGAGNYTYVVAAPQDVPARAASDPTVTVLPWGSTDVAKKVLFLRYMLPSDAFYPQSVQASQNNHTDPATTMGPYYPRAAYCDTATFEAGGAAACL
>NZ_CP009111.1|WP_065488719.1|452967_454947_+|ABC-transporter-ATP-binding-protein
MSDRATATSAERPAGPRIPGPVAPGAPGSKPNDLWPSTKRLLRRLRPHRIAVGIVLLVAAVSVVLTSIAPRMLGQGTNLIFDGIIGAQLPAGMSKDQAVAALRADGQNTFADMVSGMAVVPGVGIDFSALGRVLAIVLALYLGSSVFMWLSGFLLNIIVQGVVKNLRAEVERKIHRLPLRYFDSHSRGDLLSRVTNDIDNVSQSLQQTMSQLIVSAMTVIGILVMMIVISPLLALIAVLTVPLSILVTAQIAKRSKTHFVSQWKSTGALNSHVEEAYTGHELVTVFGRSREVEARFEEQNEALYQASYRAQFISGLIMPAIMFLGNLNFVAIAVLGGMRVASGTMSLGDVQAFIQYSRQFTQPLTQIGAMVNLMQSGVASAERVFAILDEDEEEPDLTEAPTPAEPRDAGRVHTFGRVEFSDVSFSYSPEKPLIENLSLVAEPGQMVAIVGPTGAGKTTLVNLILRFYELDGGRILLDGVDIAEMSRDDLRSRIGMVLQDAWLFGGTIRDNIAYGRPDATEEEIQAAARISYVDRFVHSLPDGYDTVIDEEGSNISAGEKQLITIARAFISQPSILILDEATSSVDTRTELLVQHATAVLRSDRTSFVIAHRLSTIRDADLIVVMEDGRIVEQGSHDDLLLTRGAYYRLYNSQFVGADV
>NZ_CP009111.1|WP_065488718.1|451237_452971_+|ABC-transporter-ATP-binding-protein
MLNALLTTYLRPYKRDLTAVVLFQLVATAAALYLPSLNADLIDNGVTKGDTGYILSTGVMMLLVTVVQIICSIGSVFFGARAAMGFGRDVRRAVMHQVGSFSSREFGRFGAPSLITRNTNDVQQVQMLVVMSCTILVMAPIMCVGGVVMSIREDAGLAWILAVTVPVLALSMGFVISRMVPAFREMQTRIDGVNRVLREQITGIRVVRAFVRERSEVARFGDANEQLTQTALRVGRLTAVMFPLVMVIANITSVAVIWFGGHEINSGTMQVGSLTAMLSYIMQILMSVMMASFIAMMAPRATVCAERIGEVLATDSTVVPPVDAVTVLENPGVVELRDAQFKFPGADEPVLRDISFRAEPGKTTAIIGGTGSGKTTLLSLIPRLIDATSGSVTVSDTEVRRIDLDVLRSGIGLVPQRPYLFSGTVATNLRYGKPDATDDELWRALEIAQAADFVRAMPEGLDTPIAQGGTTVSGGQRQRLAIARALVRRPSIYLFDDSFSALDLTTDARLRAALKPETSDACVIVVAQRVSTIVEAEQIVVLEDGAVVGIGTHDQLLETCPCYVEIVESQRSVQEAL
>NZ_CP009111.1|WP_065488717.1|448743_451092_+|MMPL-family-transporter
MATYLYRIGRFAYRRKGAVLSVWLVILVLMGVGAATLSGPTKDSFSIPGTPAQQAQDLMAERFPEAAGSDPMNAVSARYVFAAPEGQTLESEQSRQAMDAVLAKVRGIDQVQDAAKVDPATASGADAAKALVNPVTANEQLVEMAKSSAADKGIGEDAAVANAQALSPLNPDKTVGYVEVPFKGSMGDVDQALRDQISAAADAGRNAGLTVEISGSAANEAEPPGGATELVGIGVAAVVLALTFGSLVAAGLPLITAIIGIMIGSLGITVATGFTDLSSMTPTLAIMIGLAVAIDYSLFIVSRFRHELTLTDDRSEAAGRAVGTAGSAVVFAGLTVIIALIALRVVGIPFLSDMGAAAAFTVFIAVSIALTLLPAILGLFGKKAFAGKIPFLSSRDLEDDEGKPSLALRYISAVVRRPAIPLIAGVVVLGALAIPATGLSLALPSEGTGDPATSSRQAYDLVSEGFGPGKNGPLLVVVDAKDVTTGTPSEAFGEVVKTITAQDDVANAQVVGVNKAGDTAQILVTPSSAPSDPATMDLVNNIRGAEAGLHDSIGVNYGVTGQTALEGDVSETLQDALIPYLAVVVGLAFLLLLLVFRSVLVPLTATLGFLLSVAATFGATVAVFQEGWGGIISNPQPIVSFMPIFLIGVVFGLAMDYQVFLVTRMREEYVHGATAKQAVTVGFNHGARVVSAAAVIMISVFAAFIAEPNSFIKSIGFALAAAVFFDAFVVRMVIIPSVMALLGDKAWWLPKWLDKILPNVDIEGEKLKKVLHDADEPLQPVR
>NZ_CP009111.1|WP_005253325.1|448090_448693_+|TetR-family-transcriptional-regulator
MISEIGLRDRKKAATRAALSGAAARLARALGIECVTADAIASEAGVSTRTFHNYFSSKEEAVLAHFEQSVHDWVDLLRARPEDEPIWDSLEHVVVQIVTDPAKPLEETAVMMELVETSPALLAKKLEVHLRVTRLVGEVIAERTGTNIDTDLYPNLLHLAVGSACKASLDLWMSGKSGASGPEELVRDAMRQLRQGIPQP
>NZ_CP009111.1|WP_005572850.1|462345_462915_+|DUF4190-domain-containing-protein
MPRDGYGVDESGYPTYSAPTEKYPDYQQPGAYGTSPNPYAAPNRNQYGGDQYGAPNQQYGTPNPYAAPNQYSAPNQYGGAPNQYGPPGQYGGPAPQYGAPNPYGAPYPQSLGTNGLAIAALITSIVGGCFYGVGSVVGIILGIIALGQIKQSGQEGRGLAIAGIAIGGAYVVGWILFFVIMVIAAASGA
>NZ_CP009111.1|WP_005253343.1|462883_463840_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MSHPSRQSEPPSHRPAGAGRFAPSPSGDLHLGNLRTAVLAWLFARSTGRRFLMRVEDLDRVREGARDRQLADLAELGLDWDGDVVSQSHRLSRYDAAIAELHAAGLTYECFCTRREIQKAASAPHAPQGAYPGTCRNLTPDERADRLAGGRPPALRLRAGVTSFTIDDVLHGSYSGMVDDLVLRRGDGTPAYNLAVVVDDAAQGIDQVVRGDDLLSSAPRQAYLAGLLGLTTPTYAHVALALNEDGKRLAKRDGAVTLTDQKALGRTPSDVLGVLATSLGLAEPGEVVDLGILLDRFDPARLHREPWVVRLPTPPQSP
>NZ_CP009111.1|WP_005253344.1|463851_464463_-|TetR-family-transcriptional-regulator
MRERRYSSTSPERLAAALFDVAAESGLEGASVREVAKRAGVSIGAVQHHFSTKDEMFAFALRTLVDKLLTRLSEVDRGGDPARALFAAMSQLLPLDETRSREAHVMAAFAVRAATSPSLAEIRRKTLFTIRTGLSAVLIGIGTPEAETRAALLLATVDGLALDAIGSPALYPPEYLEHALDIQIGMILQGADVVPSSSIELAS
>NZ_CP009111.1|WP_065488726.1|465109_465778_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MWYWIFKYVLIGPVLRIFGRPTIDGAHHIPVSGPVILASNHLTVVDSFFLVLMVRRRITFVAKSEYFTEGGAKGRAKRWFFTAAGQVPIDRSGASAAESALNTAKKILDDGKVWGIYPEGTRSPDGRLHKGKTGIARVALATGAPVVPVAMHGTRQVNPVGSRMWRFGTVSVTVGEPLDFSRFAELRDNRHVVRAATDELMRALMTLSGQEYVDDYALRRPA
>NZ_CP009111.1|WP_037202832.1|465831_466413_+|TetR/AcrR-family-transcriptional-regulator
MIDTVYMSGEVQPLRARLIDCGRELLDDGGIDAVGLRAVARHAGVSHGAPRRYFPTHKALLAAIAASGFAELSEELRSAIVSEADPLARVRRTARQYLSFADTHRTLFELMFRHDLLEGSGEDLRLHSKPLFETVVALVADAGAETPHVVALNLWTQLHGVATLRATRSIEVIVGDFDVEAFVAQLIDLHLRA
>NZ_CP009111.1|WP_065488727.1|466402_467941_-|metallophosphatase
MSVPGRIAALTAVSLAAALLGGDVVAAADPEPRGASGLPARGLVTSAPLASAVMFAGITGDAAPSHQVPGDESNGRSATSHRFDEYPYMRYEVRFGPESAGTDVTWHGRSMNLDDLAMHVWDEEGQSWGEPVATARPSEPGGPVTLTTRIEGEDSAQILVIDGPRQDRSFREANATADQQFADPNAYDFALQHISDTQYVSRDRPEVYFDMTRWTAENAAERKIAYSMHTGDLVQSWIRPGAPESRARPEYEVADKAMATLEEAGVPYGVLPGNHDNLWNVGGRLIPGEHEKNHALYNEFFGPWRYRDQPYWGESVTDTDNSAHYDLLDIAGAKFLMLYIGYNPPEHVLQWAEDVLADHPDRNVVIGSHYYLDEDGSLRMSGFGDIGSSAGQQIWNRLVVPFETVFLVLAGHVDGQTTVTDRKVGDTDRKVVELLADYQYFTVDSRRETGFQRLLQFDLDGGTLAVTTHSPSLDSFQVEDFDPQRRYQPDDGDFVTDVELRADLPRAVLPTP
>NZ_CP009111.1|WP_005253350.1|467979_468540_-|TIGR03086-family-protein
MTSTTDTPAAHYRDLAAKFTKRVESVPAARWDDASPCDGWTARDVVRHVIDTQRYIVTVVDLELPEPPSVDDDPVAAWAATRDGMQEILNDPALVSREYDGHFGRTDLGKTIDSFYCFDLVVHGWDLARATGLDETIPAGDLTWVGGVAEQMGESIRTAGVCGPAVDVPADADEQTRVLAFLGRKA
>NZ_CP009111.1|WP_005253351.1|468536_469346_-|AraC-family-transcriptional-regulator
MGWYTPTAPSPDLTGTLVCGWSARTQGEHLLVPDACMDILWIPGVGIRVCGPETRAWSFALPPGTESVGVRFRPGAASHLLRTSAAEVRNIRVGLGDVLGSTWERKLTDRLDNAPGYAERIALFENAVRAWRTRGPEADPLIGTVRKALARHSWNVGALADAASVTERQLQRRCNDAFGYGPATLRGILRLQRFMALAQSGTRTGLAELAAAAGYSDQAHLSRECRRISSLTPSDLLTSEAPDWHGTESVVDVGNVQALGRRTGEESAA
>NZ_CP009111.1|WP_005253352.1|469501_470017_+|hypothetical-protein
MRRTWALAAIAAVSLTFSSCAYDSTDSGDTGGNAPVSPTPTSPPAAPGTPVLKMGPTTLGEVMVDDGGMTVYVYDNDEVGSGASSCRDTCLQSWPPVTSVTENPTVQGLQEVVIDTIPAADGTHQLTVNGRPVYRYKDDNEPGDAFGQAVGSVWWTLDSAGNPVTTTAGGE
>NZ_CP009111.1|WP_005253353.1|469991_470672_-|DUF1275-domain-containing-protein
MGVPIDDSKRTLALAVVLSTLAGYVDALGFITLGGFFVAFMSGNLTRFSVGFADAEWAHAATAAAVIGMFVLGCALGAVVVHLSERRRLPVRTTVLAVVSGLLIAGAVAATVGASTVAVGAMLLAMGAENSFFQRDGEVTIGLTYMTGALVKMGHRLAGALFGGPRWAWLRHFALWGGLVVGAVTGALAHHWIGLDALWFAAVLSAALTVTVHLRIDRATRRPQLS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	599308-599333	3	0.885
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1213766-1213791	3	0.885
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NZ_CP010421	Azotobacter chroococcum NCIMB 8003 plasmid pAcX50f, complete sequence	162689-162714	4	0.846
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NZ_CP010420	Azotobacter chroococcum NCIMB 8003 plasmid pAcX50e, complete sequence	95528-95553	4	0.846
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2696758-2696783	4	0.846
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NC_023067	Streptomyces sp. F2 plasmid pFP3, complete sequence	19234-19259	4	0.846
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1127315-1127340	5	0.808
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1630769-1630794	5	0.808
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1630715-1630740	5	0.808
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1118312-1118337	5	0.808
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NC_004808	Streptomyces rochei plasmid pSLA2-L DNA, complete sequence	201981-202006	5	0.808
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NC_030916	Tsukamurella phage TPA4, complete genome	10727-10752	5	0.808
NZ_CP009111_1	1.1\|38109\|26\|NZ_CP009111\|CRISPRCasFinder	38109-38134	26	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	715602-715627	5	0.808
NZ_CP009111_2	2.1\|461851\|34\|NZ_CP009111\|CRT	461851-461884	34	NZ_CP014797	Salipiger profundus strain JLT2016 plasmid pTPRO1, complete sequence	58960-58993	7	0.794
NZ_CP009111_2	2.1\|461851\|34\|NZ_CP009111\|CRT	461851-461884	34	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	280197-280230	7	0.794
NZ_CP009111_2	2.1\|461851\|34\|NZ_CP009111\|CRT	461851-461884	34	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5136212-5136245	8	0.765
NZ_CP009111_2	2.1\|461851\|34\|NZ_CP009111\|CRT	461851-461884	34	NZ_CP021821	Sinorhizobium meliloti strain M162 plasmid accessoryA, complete sequence	318642-318675	9	0.735

1. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 3, identity: 0.885

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
atcgtggtcggcgtcgccctgctggt	Protospacer
.****.******** ***********

2. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 3, identity: 0.885

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
atcgtggtcggcgtcgccctgctggt	Protospacer
.****.******** ***********

3. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NZ_CP010421 (Azotobacter chroococcum NCIMB 8003 plasmid pAcX50f, complete sequence) position: , mismatch: 4, identity: 0.846

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
ctcgtagtcggcgacgccctgctggc	Protospacer
 ************  **********.

4. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NZ_CP010420 (Azotobacter chroococcum NCIMB 8003 plasmid pAcX50e, complete sequence) position: , mismatch: 4, identity: 0.846

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
ctcgtagtcggcgacgccctgctggc	Protospacer
 ************  **********.

5. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
gtcgaagccggcgtagccctgctcgg	Protospacer
**** **.*************** *

6. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NC_023067 (Streptomyces sp. F2 plasmid pFP3, complete sequence) position: , mismatch: 4, identity: 0.846

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
gacgtcgtcggcgtagccctgccggg	Protospacer
* *** ****************.**

7. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
ccggtggtcggcgtatccctgctggt	Protospacer
 . **.********* **********

8. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.808

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
ccggtggtcggcgtatccctgctggt	Protospacer
 . **.********* **********

9. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
ccggtggtcggcgtatccctgctggt	Protospacer
 . **.********* **********

10. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.808

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
ccggtggtcggcgtatccctgctggt	Protospacer
 . **.********* **********

11. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NC_004808 (Streptomyces rochei plasmid pSLA2-L DNA, complete sequence) position: , mismatch: 5, identity: 0.808

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
caggtcgtcggcgtagccgtgctggt	Protospacer
   ** ************ *******

12. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NC_030916 (Tsukamurella phage TPA4, complete genome) position: , mismatch: 5, identity: 0.808

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
gtcgtagtcggcgtcgcccggcttcg	Protospacer
************** **** ***

13. spacer 1.1|38109|26|NZ_CP009111|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

gtcgtagtcggcgtagccctgctggt	CRISPR spacer
ccggtggtcggcgtatccctgctggt	Protospacer
 . **.********* **********

14. spacer 2.1|461851|34|NZ_CP009111|CRT matches to NZ_CP014797 (Salipiger profundus strain JLT2016 plasmid pTPRO1, complete sequence) position: , mismatch: 7, identity: 0.794

tccctgcggcggcggcgggtaattgccctgcggc	CRISPR spacer
ggcgcccggcggcggcgggtagttgccctgccgc	Protospacer
  * . ***************.********* **

15. spacer 2.1|461851|34|NZ_CP009111|CRT matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.794

tccctgcggcggcggcgggtaattgccctgcggc-	CRISPR spacer
cacgcgcggcggcggcgggggattgccct-cggcg	Protospacer
. * .************** .******** ****

16. spacer 2.1|461851|34|NZ_CP009111|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.765

tccctgcggcggcggcgggtaattgccctgcggc	CRISPR spacer
accctgcggcggcggcgggtaaccgccaccctgt	Protospacer
 *********************..*** . * *.

17. spacer 2.1|461851|34|NZ_CP009111|CRT matches to NZ_CP021821 (Sinorhizobium meliloti strain M162 plasmid accessoryA, complete sequence) position: , mismatch: 9, identity: 0.735

tccctgcggcggcggcgggtaattgccctgcggc	CRISPR spacer
agcacccggcggcggcggatagttgccctgacgc	Protospacer
  * . ************.**.********  **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3484590 : 3620812

Staphylococcus_phage(16.67%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_037206356.1\|3484590_3484917_+\|transposase	transposase	A0A1B3AZF8	Gordonia_phage	5.8e-16	51.0
WP_155772979.1\|3484913_3485597_+\|transposase	IS3 family transposase	A0A1B3AZE5	Gordonia_phage	7.6e-26	38.6
WP_155772978.1\|3485514_3485844_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.9e-06	38.2
WP_065490821.1\|3485942_3486689_-	hypothetical protein	NA	NA	NA	NA
WP_065490823.1\|3486688_3488092_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_081315334.1\|3488463_3488877_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_100228459.1\|3488936_3489575_+	serine hydrolase family protein	NA	NA	NA	NA
WP_005265081.1\|3489773_3490226_-\|protease	ATP-dependent Clp protease ClpS	A0A249XSS8	Mycobacterium_phage	2.8e-16	44.8
WP_065490825.1\|3491383_3492892_-	tripartite tricarboxylate transporter TctA	NA	NA	NA	NA
WP_005265084.1\|3492891_3493515_-	tripartite tricarboxylate transporter TctB family protein	NA	NA	NA	NA
WP_064080525.1\|3493511_3494489_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_100228460.1\|3494566_3495364_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_005265087.1\|3495785_3497159_+	C4-dicarboxylate transporter DctA	NA	NA	NA	NA
WP_005265096.1\|3497253_3497742_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_005265099.1\|3497738_3498539_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.7e-14	29.7
WP_065490827.1\|3498568_3499450_+	amidohydrolase family protein	NA	NA	NA	NA
WP_005242619.1\|3499517_3500309_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_065490828.1\|3500483_3502631_-	acetate--CoA ligase family protein	NA	NA	NA	NA
WP_005265103.1\|3502782_3503724_+	acyl-CoA thioesterase II	NA	NA	NA	NA
WP_005265104.1\|3504355_3504592_-	hypothetical protein	NA	NA	NA	NA
WP_065490829.1\|3504808_3506860_-	NAD(+) synthase	NA	NA	NA	NA
WP_005265111.1\|3509390_3509615_-	DUF3263 domain-containing protein	NA	NA	NA	NA
WP_065490832.1\|3509800_3512602_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	5.2e-12	23.4
WP_054247656.1\|3512628_3512775_-	hypothetical protein	NA	NA	NA	NA
WP_065490833.1\|3512839_3514186_-	phosphoribosyl transferase	NA	NA	NA	NA
WP_065490835.1\|3514625_3515501_+	band 7 domain-containing protein	A0A2K9KZA2	Tupanvirus	1.2e-23	28.7
WP_065490836.1\|3515850_3516123_-	hypothetical protein	NA	NA	NA	NA
WP_065490837.1\|3516320_3516779_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_065490838.1\|3516839_3517058_+	hypothetical protein	NA	NA	NA	NA
WP_065493031.1\|3517082_3517517_+	CBS domain-containing protein	A0A2I6B2H4	Macacine_betaherpesvirus	1.2e-53	69.2
WP_065490839.1\|3517575_3518013_+	hypothetical protein	NA	NA	NA	NA
WP_155772983.1\|3517954_3518275_+	hypothetical protein	NA	NA	NA	NA
WP_065490840.1\|3518379_3519879_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_065490841.1\|3519971_3522587_-	cation-transporting P-type ATPase	M1HBF8	Paramecium_bursaria_Chlorella_virus	2.2e-73	31.4
WP_005261606.1\|3522901_3524080_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_081315335.1\|3524342_3526109_-	DNA polymerase/3'-5' exonuclease PolX	E3T5M9	Cafeteria_roenbergensis_virus	1.4e-10	22.8
WP_065490842.1\|3526204_3528013_+	adenosylcobalamin-dependent ribonucleoside-diphosphate reductase	Q8V6N4	Halorubrum_phage	5.2e-90	32.1
WP_081315336.1\|3528127_3530149_-	hypothetical protein	A0A1B1ISB2	uncultured_Mediterranean_phage	1.0e-09	30.0
WP_005261593.1\|3532496_3532790_-	DUF4193 domain-containing protein	NA	NA	NA	NA
WP_080606240.1\|3532803_3533142_-	WhiB family transcriptional regulator	I6XD27	Mycobacterium_virus	3.2e-09	42.9
WP_155772984.1\|3533990_3534185_-	hypothetical protein	NA	NA	NA	NA
WP_065490848.1\|3534297_3535701_+	diguanylate cyclase	NA	NA	NA	NA
WP_065490849.1\|3536435_3536981_-	dihydrofolate reductase	NA	NA	NA	NA
WP_081315337.1\|3538106_3539417_+	histone H1	NA	NA	NA	NA
WP_155772985.1\|3540064_3540391_-	hypothetical protein	NA	NA	NA	NA
WP_065490851.1\|3540456_3541389_+	hypothetical protein	NA	NA	NA	NA
WP_081315338.1\|3542083_3542848_-	zinc permease	NA	NA	NA	NA
WP_005261581.1\|3543011_3543284_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_065490855.1\|3543569_3544706_+	YbdK family carboxylate-amine ligase	NA	NA	NA	NA
WP_005261578.1\|3546375_3546903_+	hypothetical protein	NA	NA	NA	NA
WP_065493037.1\|3546986_3547565_+	hypothetical protein	NA	NA	NA	NA
WP_037205766.1\|3547778_3548399_+	ATP-binding protein	A0A249XSS8	Mycobacterium_phage	7.7e-25	49.6
WP_065490856.1\|3548539_3548911_+	hypothetical protein	NA	NA	NA	NA
WP_005261573.1\|3549390_3549744_+	hypothetical protein	NA	NA	NA	NA
WP_155772986.1\|3549795_3549960_-	hypothetical protein	NA	NA	NA	NA
WP_065490857.1\|3550120_3551260_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.7e-33	33.5
WP_005265268.1\|3551383_3552589_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_065493039.1\|3552948_3553326_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_065493041.1\|3554090_3555281_-	fumarylacetoacetate hydrolase	NA	NA	NA	NA
WP_005264539.1\|3555277_3556747_-	aldehyde dehydrogenase (NADP(+))	NA	NA	NA	NA
WP_065490860.1\|3559518_3560400_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_065490861.1\|3561902_3562517_-	maleylpyruvate isomerase family mycothiol-dependent enzyme	NA	NA	NA	NA
WP_065493042.1\|3563029_3563536_+	polyketide cyclase	NA	NA	NA	NA
WP_065490862.1\|3563839_3564973_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_065490863.1\|3567626_3568997_+	MFS transporter	Q6JIH2	Burkholderia_virus	2.5e-28	25.6
WP_065490864.1\|3569185_3569848_+	transcriptional repressor LexA	E5DV74	Deep-sea_thermophilic_phage	5.9e-15	30.6
WP_065490866.1\|3570546_3571434_+	diiron oxygenase	NA	NA	NA	NA
WP_065490867.1\|3571450_3572854_+	NAD(P)-binding protein	NA	NA	NA	NA
WP_005262506.1\|3573153_3573510_-	hypothetical protein	NA	NA	NA	NA
WP_065489049.1\|3574145_3575384_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_005262508.1\|3576216_3577140_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_065490870.1\|3577326_3578616_+	glutamate dehydrogenase	NA	NA	NA	NA
WP_065490871.1\|3578739_3579966_-	NADH dehydrogenase	NA	NA	NA	NA
WP_065490872.1\|3580096_3580888_-	CoA ester lyase	NA	NA	NA	NA
WP_065490874.1\|3580887_3582159_-	CoA transferase	NA	NA	NA	NA
WP_005262520.1\|3582385_3583306_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005262521.1\|3583312_3584158_-	CoA ester lyase	NA	NA	NA	NA
WP_005262522.1\|3584201_3585320_-	hypothetical protein	NA	NA	NA	NA
WP_065490875.1\|3585528_3586923_-	SLC13 family permease	NA	NA	NA	NA
WP_081315341.1\|3586919_3587159_-	hypothetical protein	NA	NA	NA	NA
WP_005568870.1\|3587274_3588195_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_065490877.1\|3588464_3590051_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_065490879.1\|3590059_3590833_+	cyclase family protein	NA	NA	NA	NA
WP_065490881.1\|3590842_3593005_+	indolepyruvate ferredoxin oxidoreductase subunit alpha	NA	NA	NA	NA
WP_081315342.1\|3593001_3594657_+	indolepyruvate oxidoreductase subunit beta family protein	NA	NA	NA	NA
WP_065490884.1\|3594867_3595722_-	PaaX family transcriptional regulator	NA	NA	NA	NA
WP_065490887.1\|3595858_3597475_+	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	8.4e-39	31.3
WP_065490889.1\|3597735_3598530_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_065490891.1\|3598554_3599775_+	alanine-phosphoribitol ligase	NA	NA	NA	NA
WP_065490893.1\|3599810_3601532_+	flavin reductase family protein	NA	NA	NA	NA
WP_065489380.1\|3603004_3604138_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_155773065.1\|3611062_3611806_-	Asp/Glu racemase	NA	NA	NA	NA
WP_065490899.1\|3611887_3612784_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_065490901.1\|3612831_3613944_-	cupin domain-containing protein	NA	NA	NA	NA
WP_065490903.1\|3614143_3614554_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_065490905.1\|3614607_3616983_+	salicylyl-CoA 5-hydroxylase	NA	NA	NA	NA
WP_065490907.1\|3616982_3618017_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_005261528.1\|3619606_3620812_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

4444729 : 4493931

Catovirus(16.67%)

integrase,transposase,protease

attL 4475921:4475937|attR 4499927:4499943

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065491431.1\|4444729_4445830_-\|protease	serine protease	NA	NA	NA	NA
WP_065491432.1\|4445925_4447764_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	6.0e-33	21.3
WP_065491433.1\|4449284_4449722_-	helix-turn-helix domain-containing protein	K4ICM4	Acidithiobacillus_phage	1.7e-18	40.4
WP_065493130.1\|4450470_4451070_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_065491434.1\|4452057_4453365_-	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_065491435.1\|4453490_4455143_-	AMP-binding protein	NA	NA	NA	NA
WP_065491436.1\|4455438_4456995_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_065491437.1\|4456984_4458394_-	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	NA	NA	NA	NA
WP_065491438.1\|4458430_4459585_-	ATP-NAD kinase family protein	NA	NA	NA	NA
WP_065491439.1\|4459700_4460507_-	SDR family oxidoreductase	A0A0G2Y8L6	Acanthamoeba_polyphaga_mimivirus	2.3e-05	32.6
WP_065491441.1\|4462082_4463522_-	APC family permease	NA	NA	NA	NA
WP_065491442.1\|4464062_4464995_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_065491443.1\|4465870_4466398_-	hypothetical protein	NA	NA	NA	NA
WP_065491444.1\|4466561_4468049_-	ethanolamine permease	NA	NA	NA	NA
WP_065491445.1\|4468051_4469989_-	primary-amine oxidase	NA	NA	NA	NA
WP_081315496.1\|4470444_4471917_+	APC family permease	NA	NA	NA	NA
WP_065491447.1\|4471913_4472663_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_065491448.1\|4472921_4473911_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_065491449.1\|4473907_4474852_-\|integrase	tyrosine-type recombinase/integrase	U3PCM7	Lactobacillus_phage	2.1e-05	32.5
WP_065493131.1\|4474848_4476048_-\|integrase	tyrosine-type recombinase/integrase	A0A142K7N4	Mycobacterium_phage	4.5e-13	34.4
4475921:4475937	attL	NA	NA	NA	NA
WP_065491450.1\|4477850_4479794_+\|integrase	tyrosine-type recombinase/integrase	A0A1B1P7C7	Bacillus_phage	9.5e-05	27.2
WP_065491452.1\|4480661_4481438_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_065491453.1\|4481637_4482957_+	MFS transporter	NA	NA	NA	NA
WP_065491454.1\|4482968_4483181_+	hypothetical protein	NA	NA	NA	NA
WP_155773001.1\|4483219_4483987_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_081315497.1\|4483833_4484688_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_155773002.1\|4484267_4485569_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_081315365.1\|4485565_4487560_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_065491458.1\|4487556_4488555_+	oxidoreductase	NA	NA	NA	NA
WP_065491459.1\|4488575_4489784_+	cytochrome P450	NA	NA	NA	NA
WP_081315366.1\|4490923_4491292_+	alcohol dehydrogenase catalytic domain-containing protein	NA	NA	NA	NA
WP_065491460.1\|4491837_4493931_+\|transposase	ISAzo13 family transposase	NA	NA	NA	NA
4499927:4499943	attR	NA	NA	NA	NA

DBSCAN-SWA_3

7048960 : 7100377

Enterobacteria_phage(11.11%)

integrase,transposase

attL 7039100:7039115|attR 7083924:7083939

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
7039100:7039115	attL	NA	NA	NA	NA
WP_081315508.1\|7048960_7049323_+\|transposase	transposase	NA	NA	NA	NA
WP_065492479.1\|7049319_7050132_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	4.2e-23	31.1
WP_065492480.1\|7050605_7051319_-	hypothetical protein	NA	NA	NA	NA
WP_065492481.1\|7051323_7052064_-	hypothetical protein	NA	NA	NA	NA
WP_065493322.1\|7052483_7053179_-	type 1 glutamine amidotransferase domain-containing protein	NA	NA	NA	NA
WP_005256900.1\|7053197_7053626_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065492483.1\|7055756_7056041_-\|transposase	transposase	NA	NA	NA	NA
WP_100228443.1\|7056781_7058161_+	hypothetical protein	NA	NA	NA	NA
WP_065492484.1\|7059487_7060231_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_065492485.1\|7060463_7061531_-	hypothetical protein	NA	NA	NA	NA
WP_065492486.1\|7061749_7062766_-	PDZ domain-containing protein	B4UTS4	Rhizobium_phage	8.2e-08	29.8
WP_065492487.1\|7063552_7064056_+	hypothetical protein	NA	NA	NA	NA
WP_065492488.1\|7064059_7065940_+	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	1.4e-149	48.4
WP_065492489.1\|7065948_7066473_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_065492490.1\|7066479_7067421_+	J domain-containing protein	M1PC06	Moumouvirus	3.5e-13	51.4
WP_005563792.1\|7067417_7067747_+	hypothetical protein	NA	NA	NA	NA
WP_065492491.1\|7067728_7070362_+	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	3.1e-123	33.4
WP_065492492.1\|7070376_7070829_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	5.4e-12	41.4
WP_081315448.1\|7070825_7071092_+	UBP-type zinc finger domain-containing protein	NA	NA	NA	NA
WP_065492493.1\|7071069_7072797_+	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_037198213.1\|7072801_7073251_+	DUF1931 family protein	NA	NA	NA	NA
WP_065492494.1\|7073588_7073948_-	nicotinate phosphoribosyltransferase	E5DQ49	Aeromonas_phage	2.8e-11	41.7
WP_065493323.1\|7074106_7075744_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_065492495.1\|7076189_7076879_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_155773043.1\|7076945_7077509_-	hypothetical protein	NA	NA	NA	NA
WP_065492497.1\|7077698_7077875_-\|integrase	integrase	NA	NA	NA	NA
WP_005568205.1\|7078022_7078922_-	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_065492498.1\|7078918_7079905_-	nitronate monooxygenase	NA	NA	NA	NA
WP_005256223.1\|7079987_7080887_-	gluconolactonase	NA	NA	NA	NA
WP_065492499.1\|7081147_7082794_+	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.7e-29	24.2
WP_005568213.1\|7083103_7084711_+	GAF domain-containing protein	NA	NA	NA	NA
7083924:7083939	attR	NA	NA	NA	NA
WP_065492500.1\|7084751_7085678_-	NAD(+) diphosphatase	NA	NA	NA	NA
WP_065492501.1\|7085751_7086054_-	Dabb family protein	NA	NA	NA	NA
WP_065492502.1\|7086125_7086869_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_065493325.1\|7087096_7088029_+	alpha/beta hydrolase	A0A2L2DMU8	Acanthamoeba_polyphaga_mimivirus	3.0e-33	30.5
WP_037203513.1\|7088053_7088809_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_155773044.1\|7088925_7089444_+	acyl-CoA transferase	NA	NA	NA	NA
WP_065492503.1\|7089458_7090604_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_065492504.1\|7090603_7091632_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_011598505.1\|7091743_7092544_-	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_065492505.1\|7092716_7093622_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_065492506.1\|7093667_7095284_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_037203511.1\|7095387_7096860_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_065492507.1\|7097542_7097788_+\|transposase	transposase	NA	NA	NA	NA
WP_005256185.1\|7098115_7098400_-	hypothetical protein	NA	NA	NA	NA
WP_081315509.1\|7099300_7100377_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP009113

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP009112

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP009111

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection