CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP015409	Akkermansia muciniphila strain YL44, complete genome	2 crisprs	DinG,cas3,cas2,cas1,cas4,cas5,cas8c,cas7,DEDDh,Cas9_archaeal	1	7	1	0

1. NZ_CP015409

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015409_1

• CRISPR_ID: NZ_CP015409_1
• CRISPR_location: 1424526-1425832
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 19 spacers
• Cas_protein_info: cas2,cas1,cas4,cas3,cas5,cas8c,cas7

Consensus repeat of NZ_CP015409_1

Consensus_repeat	Method
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	PILER-CR
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CRISPRCasFinder
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CRT

spacers of NZ_CP015409_1

>1.1|1424559|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CGGCGCCCTCCGTATCTTTCTGCACCCGCACCTG
>1.2|1424626|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CTGGTGCCTTGCCAATTACGGATGCACGTTCGAG
>1.3|1424693|33|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CAGCACAGGCTCATGGTACCCGCTCAACAAAGA
>1.4|1424759|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CATATCCGTTGCGGGCTGTGTCCCGGACATTCGA
>1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CATCTTTTCGCGGGCGCTGGTGGAGGCATACTCG
>1.6|1424893|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
TTTTGACACGCTTCCGGTGACCTACCAGGACACG
>1.7|1424960|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CGGATTCCGATTCCACTGTCTCCATACGGTAGGA
>1.8|1425027|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CGCTGTTCGTGGCCTTTCCGCCTAAAAAGAGAGG
>1.9|1425094|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CATCGGCGATAATGGGAAGCGGAGGCTCCAAGCC
>1.10|1425161|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
TGTGCAAAGATTACATTATGCGGCAAATGCCGTG
>1.11|1425228|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
TGTGTGCGGGTATCAAAGACGATATATCCGAGAA
>1.12|1425295|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
GGATCCCCGCCAAAATCAACATTCAAACCCTCAA
>1.13|1425362|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CAACATGGAGGACTATTGACATGAGCCTGTCCAA
>1.14|1425429|35|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
AAGGGGAAACTCCGTGGAACAACGCTCCGTCCCCT
>1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
GGATGCCGGGGATGATGTGGCCGACCGCAACAAC
>1.16|1425564|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
GAGTTAATCCGGCATAGAAAGTTGGTGTGGTGAT
>1.17|1425631|35|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
ATGATGACCACAATTACATTGTTACACAAAAAATC
>1.18|1425699|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
CGAGCATCCCCGTGATCTGCCTGTCCCAGGAAGT
>1.19|1425766|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT
TAAGAAGTCACCTCCGTCGTGCTCAGCAAATTAA

CRISPR arrays and Neighbor proteins around NZ_CP015409_1

CRISPR arrays

The CRISPR arrays of NZ_CP015409_1

>merge|NZ_CP015409|1|1424526-1425832|PILER-CR,CRISPRCasFinder,CRT
GTTTCAGTCCACGCACTCCTTGCGGAGTGCGACCGGCGCCCTCCGTATCTTTCTGCACCCGCACCTGGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCTGGTGCCTTGCCAATTACGGATGCACGTTCGAGGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCAGCACAGGCTCATGGTACCCGCTCAACAAAGAGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCATATCCGTTGCGGGCTGTGTCCCGGACATTCGAGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCATCTTTTCGCGGGCGCTGGTGGAGGCATACTCGGTTTCAATCCACGCACTCCTTGCGGAGTGCGACTTTTGACACGCTTCCGGTGACCTACCAGGACACGGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCGGATTCCGATTCCACTGTCTCCATACGGTAGGAGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCGCTGTTCGTGGCCTTTCCGCCTAAAAAGAGAGGGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCATCGGCGATAATGGGAAGCGGAGGCTCCAAGCCGTTTCAATCCACGCACTCCTTGCGGAGTGCGACTGTGCAAAGATTACATTATGCGGCAAATGCCGTGGTTTCAATCCACGCACTCCTTGCGGAGTGCGACTGTGTGCGGGTATCAAAGACGATATATCCGAGAAGTTTCAATCCACGCACTCCTTGCGGAGTGCGACGGATCCCCGCCAAAATCAACATTCAAACCCTCAAGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCAACATGGAGGACTATTGACATGAGCCTGTCCAAGTTTCAATCCACGCACTCCTTGCGGAGTGCGACAAGGGGAAACTCCGTGGAACAACGCTCCGTCCCCTGTTTCAATCCACGCACTCCTTGCGGAGTGCGACGGATGCCGGGGATGATGTGGCCGACCGCAACAACGTTTCAATCCACGCACTCCTTGCGGAGTGCGACGAGTTAATCCGGCATAGAAAGTTGGTGTGGTGATGTTTCAATCCACGCACTCCTTGCGGAGTGCGACATGATGACCACAATTACATTGTTACACAAAAAATCGTTTCAATCCACGCACTCCTTGCGGAGTGCGACCGAGCATCCCCGTGATCTGCCTGTCCCAGGAAGTGTTTCAATCCACGCACTCCTTGCGGAGTGCGACTAAGAAGTCACCTCCGTCGTGCTCAGCAAATTAAGTTTCAATCCACGCACTCCTTGCGGAGTGCGAC

>NZ_CP015409|1|1|1424526-1425832|PILER-CR
GTTTCAGTCCACGCACTCCTTGCGGAGTGCGAC	CGGCGCCCTCCGTATCTTTCTGCACCCGCACCTG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CTGGTGCCTTGCCAATTACGGATGCACGTTCGAG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CAGCACAGGCTCATGGTACCCGCTCAACAAAGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATATCCGTTGCGGGCTGTGTCCCGGACATTCGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATCTTTTCGCGGGCGCTGGTGGAGGCATACTCG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TTTTGACACGCTTCCGGTGACCTACCAGGACACG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGGATTCCGATTCCACTGTCTCCATACGGTAGGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGCTGTTCGTGGCCTTTCCGCCTAAAAAGAGAGG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATCGGCGATAATGGGAAGCGGAGGCTCCAAGCC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TGTGCAAAGATTACATTATGCGGCAAATGCCGTG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TGTGTGCGGGTATCAAAGACGATATATCCGAGAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GGATCCCCGCCAAAATCAACATTCAAACCCTCAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CAACATGGAGGACTATTGACATGAGCCTGTCCAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	AAGGGGAAACTCCGTGGAACAACGCTCCGTCCCCT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GGATGCCGGGGATGATGTGGCCGACCGCAACAAC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GAGTTAATCCGGCATAGAAAGTTGGTGTGGTGAT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	ATGATGACCACAATTACATTGTTACACAAAAAATC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGAGCATCCCCGTGATCTGCCTGTCCCAGGAAGT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TAAGAAGTCACCTCCGTCGTGCTCAGCAAATTAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC

>NZ_CP015409|1|1|1424526-1425832|CRISPRCasFinder
GTTTCAGTCCACGCACTCCTTGCGGAGTGCGAC	CGGCGCCCTCCGTATCTTTCTGCACCCGCACCTG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CTGGTGCCTTGCCAATTACGGATGCACGTTCGAG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CAGCACAGGCTCATGGTACCCGCTCAACAAAGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATATCCGTTGCGGGCTGTGTCCCGGACATTCGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATCTTTTCGCGGGCGCTGGTGGAGGCATACTCG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TTTTGACACGCTTCCGGTGACCTACCAGGACACG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGGATTCCGATTCCACTGTCTCCATACGGTAGGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGCTGTTCGTGGCCTTTCCGCCTAAAAAGAGAGG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATCGGCGATAATGGGAAGCGGAGGCTCCAAGCC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TGTGCAAAGATTACATTATGCGGCAAATGCCGTG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TGTGTGCGGGTATCAAAGACGATATATCCGAGAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GGATCCCCGCCAAAATCAACATTCAAACCCTCAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CAACATGGAGGACTATTGACATGAGCCTGTCCAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	AAGGGGAAACTCCGTGGAACAACGCTCCGTCCCCT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GGATGCCGGGGATGATGTGGCCGACCGCAACAAC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GAGTTAATCCGGCATAGAAAGTTGGTGTGGTGAT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	ATGATGACCACAATTACATTGTTACACAAAAAATC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGAGCATCCCCGTGATCTGCCTGTCCCAGGAAGT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TAAGAAGTCACCTCCGTCGTGCTCAGCAAATTAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC

>NZ_CP015409|1|1|1424526-1425832|CRT
GTTTCAGTCCACGCACTCCTTGCGGAGTGCGAC	CGGCGCCCTCCGTATCTTTCTGCACCCGCACCTG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CTGGTGCCTTGCCAATTACGGATGCACGTTCGAG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CAGCACAGGCTCATGGTACCCGCTCAACAAAGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATATCCGTTGCGGGCTGTGTCCCGGACATTCGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATCTTTTCGCGGGCGCTGGTGGAGGCATACTCG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TTTTGACACGCTTCCGGTGACCTACCAGGACACG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGGATTCCGATTCCACTGTCTCCATACGGTAGGA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGCTGTTCGTGGCCTTTCCGCCTAAAAAGAGAGG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CATCGGCGATAATGGGAAGCGGAGGCTCCAAGCC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TGTGCAAAGATTACATTATGCGGCAAATGCCGTG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TGTGTGCGGGTATCAAAGACGATATATCCGAGAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GGATCCCCGCCAAAATCAACATTCAAACCCTCAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CAACATGGAGGACTATTGACATGAGCCTGTCCAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	AAGGGGAAACTCCGTGGAACAACGCTCCGTCCCCT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GGATGCCGGGGATGATGTGGCCGACCGCAACAAC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	GAGTTAATCCGGCATAGAAAGTTGGTGTGGTGAT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	ATGATGACCACAATTACATTGTTACACAAAAAATC
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CGAGCATCCCCGTGATCTGCCTGTCCCAGGAAGT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TAAGAAGTCACCTCCGTCGTGCTCAGCAAATTAA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015409.2|WP_065529280.1|1419845_1420727_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_065529287.1|1427354_1428023_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NZ_CP015409.2|WP_065529292.1|1435185_1436340_-|acyltransferase	unknown	unknown	gnl|CDD|376607
NZ_CP015409.2|WP_065529281.1|1420997_1422632_-|hypothetical-protein	unknown	unknown	gnl|CDD|378829
NZ_CP015409.2|WP_128153555.1|1422640_1422847_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_065529278.1|1417520_1417865_-|rubrerythrin	unknown	unknown	gnl|CDD|275328
NZ_CP015409.2|WP_065529283.1|1423843_1424137_+|hypothetical-protein	unknown	unknown	gnl|CDD|367747
NZ_CP015409.2|WP_065529289.1|1430613_1431309_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187534
NZ_CP015409.2|WP_065529279.1|1418147_1418492_-|rubrerythrin	unknown	unknown	gnl|CDD|275328
NZ_CP015409.2|WP_065529285.1|1426033_1426324_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NZ_CP015409.2|WP_031931491.1|1423172_1423793_+|hypothetical-protein	unknown	unknown	gnl|CDD|222807
NZ_CP015409.2|WP_065529293.1|1437520_1441102_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143443
NZ_CP015409.2|WP_065529284.1|1424133_1424391_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_065529290.1|1431325_1433317_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl|CDD|187887
NZ_CP015409.2|WP_084042737.1|1428119_1430591_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP015409.2|WP_012421083.1|1420719_1421001_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_065529286.1|1426338_1427358_-|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|188360
NZ_CP015409.2|WP_143246799.1|1436831_1437317_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_065529291.1|1433359_1434184_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl|CDD|187820
NZ_CP015409.2|WP_012421081.1|1418672_1419176_-|thioredoxin-family-protein	unknown	unknown	gnl|CDD|379034

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP015409.2|WP_065529287.1|1427354_1428023_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	6.2e-39	128.7	0.0
NZ_CP015409.2|WP_065529290.1|1431325_1433317_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	8.5e-143	471.5	0.0
NZ_CP015409.2|WP_084042737.1|1428119_1430591_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	4.3e-54	178.6	0.0
NZ_CP015409.2|WP_065529286.1|1426338_1427358_-|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	1.9e-135	446.0	0.0
NZ_CP015409.2|WP_065529289.1|1430613_1431309_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	4.4e-63	207.4	0.0
NZ_CP015409.2|WP_065529291.1|1433359_1434184_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	8.8e-98	321.8	0.1
NZ_CP015409.2|WP_065529285.1|1426033_1426324_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	7.6e-29	94.7	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP015409.2|WP_065529287.1|1427354_1428023_-|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	4.2264e-45
NZ_CP015409.2|WP_065529292.1|1435185_1436340_-|acyltransferase	gnl|CDD|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	1.98014e-16
NZ_CP015409.2|WP_065529281.1|1420997_1422632_-|hypothetical-protein	gnl|CDD|378829	pfam12236, Head-tail_con, Bacteriophage head to tail connecting protein. This family of head-tail connector proteins is found in bacteria and viruses. Proteins in this family are typically between 516 and 555 amino acids in length. This protein is found in Phage T7 and T3 among others.	7.54744e-156
NZ_CP015409.2|WP_084042737.1|1428119_1430591_+|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.04105e-44
NZ_CP015409.2|WP_065529283.1|1423843_1424137_+|hypothetical-protein	gnl|CDD|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	1.32258e-06
NZ_CP015409.2|WP_065529289.1|1430613_1431309_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	4.79232e-90
NZ_CP015409.2|WP_031931491.1|1423172_1423793_+|hypothetical-protein	gnl|CDD|222807	PHA00662, PHA00662, hypothetical protein.	9.5243e-22
NZ_CP015409.2|WP_065529285.1|1426033_1426324_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.15785e-31
NZ_CP015409.2|WP_065529279.1|1418147_1418492_-|rubrerythrin	gnl|CDD|275328	TIGR04535, conserved_hypothetical_protein, ferritin-like protein. Two families of proteins are known to be encoded, with some regularity, next to the gene for encapsulin (pfam04454), with surrounds the target protein to form a prokaryotic proteinaceous organelle. One is the family of enzymes that includes Dyp-type peroxidases. The other is this family, with a resemblance to bacterioferritins. Encapsulin-associated forms of the proteins in these two families have a necessary C-terminal motif that resembles DGSL[SGN]IGSL[KR]. Members of this family that include the last columns of the model in the hit region (and are encoded next to the encapsulin gene) should be designated encapsulin-associated ferritin-like protein.	8.82131e-18
NZ_CP015409.2|WP_065529290.1|1431325_1433317_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	4.80679e-136
NZ_CP015409.2|WP_065529278.1|1417520_1417865_-|rubrerythrin	gnl|CDD|275328	TIGR04535, conserved_hypothetical_protein, ferritin-like protein. Two families of proteins are known to be encoded, with some regularity, next to the gene for encapsulin (pfam04454), with surrounds the target protein to form a prokaryotic proteinaceous organelle. One is the family of enzymes that includes Dyp-type peroxidases. The other is this family, with a resemblance to bacterioferritins. Encapsulin-associated forms of the proteins in these two families have a necessary C-terminal motif that resembles DGSL[SGN]IGSL[KR]. Members of this family that include the last columns of the model in the hit region (and are encoded next to the encapsulin gene) should be designated encapsulin-associated ferritin-like protein.	1.76902e-18
NZ_CP015409.2|WP_065529286.1|1426338_1427358_-|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl|CDD|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	3.5402e-173
NZ_CP015409.2|WP_065529293.1|1437520_1441102_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl|CDD|143443	cd07125, ALDH_PutA-P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA. The proline catabolic enzymes of the aldehyde dehydrogenase (ALDH) protein superfamily, proline dehydrogenase and Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH, (EC=1.5.1.12 )), catalyze the two-step oxidation of proline to glutamate; P5CDH catalyzes the oxidation of glutamate semialdehyde, utilizing NAD+ as the electron acceptor. In some bacteria, the two enzymes are fused into the bifunctional flavoenzyme, proline utilization A (PutA) These enzymes play important roles in cellular redox control, superoxide generation, and apoptosis. In certain prokaryotes such as Escherichia coli, PutA is also a transcriptional repressor of the proline utilization genes.	0
NZ_CP015409.2|WP_065529291.1|1433359_1434184_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.32846e-114
NZ_CP015409.2|WP_012421081.1|1418672_1419176_-|thioredoxin-family-protein	gnl|CDD|379034	pfam13098, Thioredoxin_2, Thioredoxin-like domain.	1.707e-13

Protein sequences

>NZ_CP015409.2|WP_065529284.1|1424133_1424391_+|hypothetical-protein
MKNPLLSTEEKRRWLARVFRDEDGEYSQADKFKALVEDTKLATLQQEEEEFKRQREMGAEPQDPILALLQSLPPAELNLNNHPSS
>NZ_CP015409.2|WP_065529283.1|1423843_1424137_+|hypothetical-protein
MKALDFIQIFASNVRRLDFRLSSAQVILAVIAGYRRHSTITEATRLHPNTVTNILQDLIAQGYVNRIGDGRPYVYRPTADGEQLAGNLLDKNTFPGI
>NZ_CP015409.2|WP_031931491.1|1423172_1423793_+|hypothetical-protein
MINESLLQPDTPSALDICNAALSKIGEAPLDALIANESTASRLCVLHYHPARRETLCMARWTFAATQTTLDSVSAQAPNSLTPYQFTLPADCLRVLDVECSEWKMQGRRIHASCAPLPLSYIADIENADQFDPLFMDALATRLAEKLAMPLTGNQSLRQNLNQEFHKIILPQAATVNAVQCFSNDSHPLLDLLRKIKSPSCPEECE
>NZ_CP015409.2|WP_128153555.1|1422640_1422847_-|hypothetical-protein
MKPSTPSASAPEQTIPVKAESVEQEVGEDYQARERQRQGMISTILARRHSSAGQGEVNPRTLLRKTLG
>NZ_CP015409.2|WP_065529281.1|1420997_1422632_-|hypothetical-protein
MEERVAELNSVYKSLAAQRAPWETWWDRLRDYVLPRRLNREGEVSLPNRDAMDRMTDTTAVEACQKLASGHMSYITPSHDVWFKWSAPDDRGGDEAEAWYNQCSEIALKELSVSNFYTEIHECFLDRVALGTGSLFTGTSSDGRLLFTNIPCGQFACAENAEGRVDTYVREFTYTAHQARSMFGVKALGPKAREVLERGGNPYATTLRFLHVVRPRTRRSRRREQASHMPFESVYLSLDDQVIVEEGGYMEFPYLVTRFLKWGSGPYGLAPGRLVFPAIQQVQFLNRILDTLGEVAAFPRILELANQIGEVDLRAGGRTVITPEAASLHLPREWATQGRYDVGMDRLAQKQDAIRRAYYLPMLELWSGHRGNMTATEVMARENERVLMFSPSFTLFVSDLYSTMTRIFSLLFRMGKFPRPPRAVLRVGRDGSVAVGEPRVVYQSKIALVLRRLQSEGMDRSLQRLNMMMQAAPDLADHVDWDHCFRLSARVDGAPESMLRPWADVRAMRKERVDLQQGASLAPAEEDPYASLNPLLDQLTAIQK
>NZ_CP015409.2|WP_012421083.1|1420719_1421001_-|hypothetical-protein
MNQDTTLQQEASVREARFKRRQLLRVFDTPDGRETLSFLEARFQTDLPVFQGSPGNYDPLDAMRRDAYREIFLYIRRQLQLAIKETTEEEKND
>NZ_CP015409.2|WP_065529280.1|1419845_1420727_-|hypothetical-protein
MIDSIDNSMAAPIRDAEGSGAVSPETDALSETAVQTEPFPPLLGEDGGFAPDWYARFDELKGMEKSLSKFKTPEALAKSYAELERLRRYPGVENEEQMARFRRLAGLPESEEEYRLERPESTPESEWNAGLAERMARTAYRYGVPPEAMNALQETMAQAYDEAREHMEDARMEMEMQAEQSLQQEWGANYERNMGRATAVLRRLASETGVDADALLDNPGLGSNPDAIRLLYQASRLLDEAPLHHTGNAAPSPAEEAMRMESDPSHPLYEAYMNVNHPNHKYANELYDRLTTR
>NZ_CP015409.2|WP_012421081.1|1418672_1419176_-|thioredoxin-family-protein
MMNRHFIFALCTVLGFSVSGISMAQSVPTDKEAAAKAAKAAKVKFRWGKSLKSAQKQAEETGLPIVLLFTGTSWCGFCVKLEKEILSKKDFKQGMDGVAIGVKFEFGSSDFSKSKEAKTYNITGVPAMVVVDADGKELGRTGYVPGRTPAQYVEFFKKYAPKTAEGK
>NZ_CP015409.2|WP_065529279.1|1418147_1418492_-|rubrerythrin
MPEFTNAFSGLKEDRKLTHDELVRAIRFMIAAEYESIQLYTQLAASIDDKLAQEVLWDISNEEKEHAGEFLRLLQVLAPDEQGFYDEGMGETNEKIDKLKASCPDGACGSSAAH
>NZ_CP015409.2|WP_065529278.1|1417520_1417865_-|rubrerythrin
MPEFTNAFSGLKENRKLTHDELVRAIRFMIAAEYEAIQLYTQLAESIDHKLAQEVLLDISNEEKEHAGEFLRLLQVLAPDEQGFYDEGMGETNEKIDKLKASCPDGACSSSASH
>NZ_CP015409.2|WP_065529285.1|1426033_1426324_-|CRISPR-associated-endonuclease-Cas2
MYILITYDVATDDKAGQRRLRQVARACENVGQRVQNSVFECELPPAQLVDIRNKLLKIIDSESDSLRIYHMGSNWHHKIEQLGKEKSYDIFGPLII
>NZ_CP015409.2|WP_065529286.1|1426338_1427358_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKHLNTLFVTLEGCWLSKDGDTVKVNAEGTCLLRVPLHNLEGIVTLGWDIGVSPYLMGACAERGITLSFCNPYGKFLAGVQGFMKGNILLRREQYRWADDEARWVGVAREMIGAKIANCRSLLLRAQRTYGKDLSEAIDRLAAFCSMARGCNSGDMLRGIEGSAAETYFSCLSHCQRTEDPELVFESRNRRPPKDCFNALLSFLYSLLCHDARSALESSGIDAAAGFLHRDRPGRPGMALDLMEEFRAPLADRLALTLINRKQISSDDFDKEESGAVFLKEDSRKKVLNAWQERKKTVLVHPFLQEKTTLGLLIHIQALLLARHLRGDLDCYTPFIGK
>NZ_CP015409.2|WP_065529287.1|1427354_1428023_-|CRISPR-associated-protein-Cas4
MSSSFFSVPLAALQHYLYCPRQCALIHLECAWADNQFTAEGNVFHERADSGMTENRGRKRILRSLHISSLQWGIHGIADVVEVVYAEKGGIPVSMTPVEYKVGKPKPHRADEVQVCAQALCLEEMFGLEIPSGFLFYGKTQKRMEVVFDEELRILTAEAIRNAREVLTGEVTPPPMYSKACKSCSLVNDCLPDVCREHRQTMKARVDSVFEDSLETSEADDL
>NZ_CP015409.2|WP_084042737.1|1428119_1430591_+|CRISPR-associated-helicase/endonuclease-Cas3
MYQARPHQSLSTHEQECARTMSTLLAPLGLSQFGALIGGMHDFGKMSADFQQYMDALSQHISPPIPKGGIDHSTAGAQFVWNYFPIPEDSEEFFIFRQIIALCIASHHNSALIDCFRGTMPGDDVFSKRMEKSGEKTHLDEILSKLTFQEKEHYYSLLKKTELATEFKNVYTLLTTLFGHCPKKQAFHAGLIARFCLSSLIEADYTSASGKGSYESIPEPDWEGMLKNLNKHLEQFKADTPINQSRAAMSQECLQAAPGRVGKWNLTLPTGAGKTLSSLRFALEHARRHHLSRIIYIIPYTSILDQTANAIRKVLGNEYKDCILEHHSNLVKETLNKEGEMEPWSPERKTWYMEATQTWNVPIVLTTSVQYLNALYASGKQYVRRMHSLANAVVIFDEVQAIPPTSLRLFEHSLDFLAGICHSSTIRCTATPPETATEDGTHAHLIETPIIPDSQAYFDQFSQFRQCEVVCERKPSNYWTVEKMRDFIMEQASSKSPTLVIVNTKKLASKLACACQDLNTEADVFHLSTNMCPAHRKEIITNRIDKKSLEKARRKGKAVVCISTGLIEAGVDVDFDVIIRSVAGLDSCTQAAGRCNRDANRSGGRVILINPAGNLERLDFLPELEIGREIAMGMICDPEEGGILGNKSVSLYFKEFYGKLTRSHNHDHLSYPFICSNVATNMEDALSQNFKLMTHPRQQSKYAPLRLFQAFDSAARQYHPIKDDTIAVITPYGRGEECREKLWNMNPHTDEEWEQWNEWLQKARAYSVAISSQLLEKYLNSGDIMRIQEGVDIYTTIPNKYDPFLGFLTDPGETSGALTVSRI
>NZ_CP015409.2|WP_065529289.1|1430613_1431309_+|type-I-C-CRISPR-associated-protein-Cas5
MLNQIEFKVYGKYALFSDPLTRIGGEKCSYQIPTYEALKGIVKAVYWKPTLIWLIDEVRIMRPIRLVPKNMKLIKYHEAGADLSVYTYLQDVEYQVKAHFEWNMYRPDMSKDRIDGKHYEIARRMIDRGGRRDIALGTRECQGYVEPCRFGEGKGFYDQYGDTSFGLMFHGFNYPDETGKEELSIRFWRPVMENGKIRFVRPEACEIVKHVRPMAACPPRSSGLNDLSLGE
>NZ_CP015409.2|WP_065529290.1|1431325_1433317_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MNWMYALYATYEQNRDYVGRIDKEPAHGNRKERLITPLLPLYHSMQNAHITITLNRQGELIDASLNNQNSQPTIIPVTEASGGRTSGACAHPLCDKLQYVAGDNADYFPPEKSPAKRTKQLKTLQASYEQYEQQLSEWAAFDPGNVKLNAVLAYIRKKSLIRDLIKKEILHVEDSTNTLLPVWKGDKQEMPAIFEFLGASTQENAFIRWKINNKDGNPPEVYEDPAMYESWRIYTESKANKEGMCYVLGKTAPLATTHPARIRNAGDKAKLISSNDSSGYTYRGRFIEADEACGVSTEVTQKAHSALRWLISRQGWYDGDLVVLAWSPGLLKVPSPCGNVQEWEHYTPDQPTPNDQVTQLVKQFKKELSGGGKELLRTSLNENDIKNRVLVLSLNSASPGRMSLSSFQEFTVSEYLNNLLSWHSKASWKQHLPKDKEGNDRSYIGAPSISMIVKAAYGIKVDDKLRKHALSRLLPCILYNLPIPPDLEKQCVIQASKRHAMEWWEWEMTLGVSCSVYLYNHPQTNTSSSDTMSLDPKITDRSYLFGRLLAVAEAIETSALNITKTSRPTNAEKLMQRFQQRPSETWSMLEKSIQPYRNILKKNENTVSFLRSYDAYIDNIMETFLMGQFMDNGPLTGAYLLGYHCQRAFIYKTKEEKNAELAK
>NZ_CP015409.2|WP_065529291.1|1433359_1434184_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSLNHKIDFAVIFTVTNANPNGDPLDGNRPRTTLEGLGEISDVCLKRKIRNKLMDMGQNIFVQSDDRRVDDYKTLKERATPILKQKGTSAELAQKACQEWYDVRAFGQVFALKDKDAAKGTGVSIGIRGPVTIQPAFSKDTVNITSTQITKSVSNDGDGSKKSSDTMGMKHRVDKGTYVFFGAINPQLAELTGFSDEDASIFKQVLPQMFEGDASSARPEGSMSIQKVIWWEHNCKSGQYSSAKVHHSIEISEDGNIVKKYDLPGLTPEMIEGF
>NZ_CP015409.2|WP_065529292.1|1435185_1436340_-|acyltransferase
MNANQSLNSLGSHIAWVGFLRILACFLVVLAHCCDPFVGSFDGSFNFKSAVFWGSLVRPCVPLFAMISGVLLFPVTLEMGAFYSRRLKRVLVPLIVWSLALPLLYFGYFAAGVQTDSPNIVMDTYTWSATVGKLYTFFFNFNYDTTPLWYVYMLVGLYLFMPIMSAWLAQARRKDVKIFLGIWIFSMTLPYIQMLAPALGYEGNYGNMGILGVCDWNPYGMFYNFSGFLGYMVLAHYLTKYPLAWSWKKMLSITIPLFLIGFAVTFFGFLETQKHFPGQYSKLEVLWYFSGINVFLMTFAIFAVVSRLRIKAGPVLSKVAALTFGVYLCHFFFVQCSYDFVNFIGLGGLPSAVKIPLMACLASAVSAALVWLLSLNRWTRKSIM
>NZ_CP015409.2|WP_143246799.1|1436831_1437317_-|hypothetical-protein
MNASPKKLEMQNLKNNEASPSVNTFTYKVLRIIITTTILTIIYAFPADKEALSYYDLIIQSLILAFSSSLGIFYIIPFSFQALKRAKQSYILDSPSKTIAYALIVIVSMLSWYWITDSIIQSITGYPIEGLYHSKSPQYRYRYSKAYKIRAERLKIQRGEF
>NZ_CP015409.2|WP_065529293.1|1437520_1441102_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MTDSSIPDMMAEARRGQWTDQQLAAKAVELAEFILKQSNAGMRGKEKRQAQQMERMMNDPAGKAFTLALADRVFRPSSPARGAELFRYLLDGYGVPRYLSAADRFAMKMGGRFSAQFPGVVMPMITSQLRKESSNVILPAEDGKLRPHLRRRRKGGIRMNINQLGEAILGESEAHHRLQQVVDRLTDKDCDYISVKISAIFSQIHLVAFEETVKLIQERLRILYRAAITNAVTLPDGSRKPKFVNLDMEEYRDLHLTAEAFKRTLMEDEFMQLEAGIVLQAYLPDSWEEQMKLCAWAKERVEQGGARIKIRLVKGANLAMEKVEASMHGWAQAPYGTKAQVDANYKRMLHYGCMPDNARYVQFGVASHNLFDLCYAMLLREREGVRDQVEFEMLEGMANHQARVIRQAADGLLLYAPVVLKEDFHSAIAYLVRRLDENTSEENFLHDLFGMTPGSRSWEVQKKRFLKACQEKDEVKYGPNRTQNRAADPIQPSHYRDAFANERDTDWSLRQNAEWINGLIAAEKEKSGEEIPLVIDGEEITTNLWGVGRDPSRHNEVSYKFAYADFDQVEHALVTADRARSSWASKSIGERAEILHRAAQELSRIRGEAIAAMVRDAGKAPTEADVEVSEAIDFCRYYAEGLNRDGMNDGVEMSPLGTICVMSPWNFPFAIPTGGVAAALMAGNAVVFKPSELAVYTAWQIVQAFWRAGVPKNVLQFVPMPRNEISRKFLMDPRLNGVIMTGSYRTGKMLRELRPDLHVLAETSGKDAMIITATADPDQAVKDLVKSAFGHSGQKCSAASVAIVEASVYDNPAFLRQLKDAAASLKVGGSWEVNSVVTPLIREPEGNLLRALTQLEPGEEWLLKPEPSEDNPCLWSPGIRLGVKPGSWFHQTECFGPVLGIIRAENLEEAIDIQNDSEFGLTGGLQSLDEREIALWKTKVQVGNAYINRVITGAIVRRQPFGGWNHSSMGPGAKAGGPNYLTMLGSWEEKALPQKLRTPGERISGLVEKLCSELPDCAKRIRSAAGSQAKWWMEEFGVDHDPSRVYGENNIFRYTPVKGILARVENMSDDDVAILLLGAKLCGVLLHLSIGASRPWIQKMHGYYASLTVETEAELIGRMPEALQGVRFLRGTDISEALVNAAHARDVEVLDRPVLANGRLELLGYFREQAVSETVHRYGNLIPPPGSFKANRA

Crispr_ID: NZ_CP015409_2

• CRISPR_ID: NZ_CP015409_2
• CRISPR_location: 1434304-1434788
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas7,cas8c,cas5,cas3,cas4,cas1,cas2

Consensus repeat of NZ_CP015409_2

Consensus_repeat	Method
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CRISPRCasFinder
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CRT
GTTTCAATCCACGCACTCAT--GAGAGTGCGAC	PILER-CR

spacers of NZ_CP015409_2

>2.1|1434335|34|NZ_CP015409|CRISPRCasFinder,CRT
CCTGATGCGCATTGCGGAAAGGAGCCGGAAAAAG
>2.2|1434400|34|NZ_CP015409|CRISPRCasFinder,CRT,PILER-CR
GCCGATGCACCACGTGCCGGGTACGTTGTTGGTC
>2.3|1434465|34|NZ_CP015409|CRISPRCasFinder,CRT,PILER-CR
CTCAAATCCTTCCCTTTCATACTCACTCCCTCCA
>2.4|1434530|34|NZ_CP015409|CRISPRCasFinder,CRT,PILER-CR
CCGGCTGGTTGACGGGAACCCTCAACACTTAGCC
>2.5|1434595|33|NZ_CP015409|CRISPRCasFinder,CRT,PILER-CR
TCCGGAGTTGAACCGTCCGACTGCCTGAATGCC
>2.6|1434659|34|NZ_CP015409|CRISPRCasFinder,CRT,PILER-CR
CATAGGGAAATAATAACCTATAAGGGTTGTAAAG
>2.7|1434724|34|NZ_CP015409|CRISPRCasFinder,CRT,PILER-CR
TATATATTTTTGTATCCATAAAACAGTTTTGTAA

CRISPR arrays and Neighbor proteins around NZ_CP015409_2

CRISPR arrays

The CRISPR arrays of NZ_CP015409_2

>merge|NZ_CP015409|2|1434304-1434788|CRISPRCasFinder,CRT,PILER-CR
ATCTAAATCCACGCACTCATGAGAGTGCGACCCTGATGCGCATTGCGGAAAGGAGCCGGAAAAAGGTTTCAATCCACGCACTCATGAGAGTGCGACGCCGATGCACCACGTGCCGGGTACGTTGTTGGTCGTTTCAATCCACGCACTCATGAGAGTGCGACCTCAAATCCTTCCCTTTCATACTCACTCCCTCCAGTTTCAATCCACGCACTCATGAGAGTGCGACCCGGCTGGTTGACGGGAACCCTCAACACTTAGCCGTTTCAATCCACGCACTCATGAGAGTGCGACTCCGGAGTTGAACCGTCCGACTGCCTGAATGCCGTTTCAATCCACGCACTCATGAGAGTGCGACCATAGGGAAATAATAACCTATAAGGGTTGTAAAGGTTTCAATCCACGCACTCATGAGAGTGCGACTATATATTTTTGTATCCATAAAACAGTTTTGTAAGTTTCAATCCACGCACTCATGAGAGTGCGAC

>NZ_CP015409|2|2|1434304-1434788|CRISPRCasFinder
ATCTAAATCCACGCACTCATGAGAGTGCGAC	CCTGATGCGCATTGCGGAAAGGAGCCGGAAAAAG
GTTTCAATCCACGCACTCATGAGAGTGCGAC	GCCGATGCACCACGTGCCGGGTACGTTGTTGGTC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CTCAAATCCTTCCCTTTCATACTCACTCCCTCCA
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CCGGCTGGTTGACGGGAACCCTCAACACTTAGCC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	TCCGGAGTTGAACCGTCCGACTGCCTGAATGCC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CATAGGGAAATAATAACCTATAAGGGTTGTAAAG
GTTTCAATCCACGCACTCATGAGAGTGCGAC	TATATATTTTTGTATCCATAAAACAGTTTTGTAA
GTTTCAATCCACGCACTCATGAGAGTGCGAC

>NZ_CP015409|2|2|1434304-1434788|CRT
ATCTAAATCCACGCACTCATGAGAGTGCGAC	CCTGATGCGCATTGCGGAAAGGAGCCGGAAAAAG
GTTTCAATCCACGCACTCATGAGAGTGCGAC	GCCGATGCACCACGTGCCGGGTACGTTGTTGGTC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CTCAAATCCTTCCCTTTCATACTCACTCCCTCCA
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CCGGCTGGTTGACGGGAACCCTCAACACTTAGCC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	TCCGGAGTTGAACCGTCCGACTGCCTGAATGCC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CATAGGGAAATAATAACCTATAAGGGTTGTAAAG
GTTTCAATCCACGCACTCATGAGAGTGCGAC	TATATATTTTTGTATCCATAAAACAGTTTTGTAA
GTTTCAATCCACGCACTCATGAGAGTGCGAC

>NZ_CP015409|2|2|1434369-1434788|PILER-CR
GTTTCAATCCACGCACTCATGAGAGTGCGAC	GCCGATGCACCACGTGCCGGGTACGTTGTTGGTC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CTCAAATCCTTCCCTTTCATACTCACTCCCTCCA
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CCGGCTGGTTGACGGGAACCCTCAACACTTAGCC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	TCCGGAGTTGAACCGTCCGACTGCCTGAATGCC
GTTTCAATCCACGCACTCATGAGAGTGCGAC	CATAGGGAAATAATAACCTATAAGGGTTGTAAAG
GTTTCAATCCACGCACTCATGAGAGTGCGAC	TATATATTTTTGTATCCATAAAACAGTTTTGTAA
GTTTCAATCCACGCACTCATGAGAGTGCGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015409.2|WP_031931505.1|1449605_1450202_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP015409.2|WP_065529287.1|1427354_1428023_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NZ_CP015409.2|WP_102741624.1|1441261_1442239_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_065529298.1|1448724_1449300_-|rubrerythrin-family-protein	unknown	unknown	gnl|CDD|153100
NZ_CP015409.2|WP_065529293.1|1437520_1441102_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143443
NZ_CP015409.2|WP_065529292.1|1435185_1436340_-|acyltransferase	unknown	unknown	gnl|CDD|376607
NZ_CP015409.2|WP_051729719.1|1443230_1445486_+|catalase-HPII	unknown	unknown	gnl|CDD|236886
NZ_CP015409.2|WP_084042737.1|1428119_1430591_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP015409.2|WP_065529283.1|1423843_1424137_+|hypothetical-protein	unknown	unknown	gnl|CDD|367747
NZ_CP015409.2|WP_065529289.1|1430613_1431309_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187534
NZ_CP015409.2|WP_031931491.1|1423172_1423793_+|hypothetical-protein	unknown	unknown	gnl|CDD|222807
NZ_CP015409.2|WP_065529285.1|1426033_1426324_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NZ_CP015409.2|WP_065529284.1|1424133_1424391_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_065529290.1|1431325_1433317_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl|CDD|187887
NZ_CP015409.2|WP_065529299.1|1450276_1450906_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_088358250.1|1445982_1448676_-|hypothetical-protein	unknown	unknown	gnl|CDD|274447
NZ_CP015409.2|WP_065529291.1|1433359_1434184_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl|CDD|187820
NZ_CP015409.2|WP_143246799.1|1436831_1437317_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP015409.2|WP_065529286.1|1426338_1427358_-|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|188360
NZ_CP015409.2|WP_031931498.1|1442256_1442706_-|KH-domain-containing-protein	unknown	unknown	gnl|CDD|224760

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP015409.2|WP_065529287.1|1427354_1428023_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	6.2e-39	128.7	0.0
NZ_CP015409.2|WP_065529285.1|1426033_1426324_-|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	7.6e-29	94.7	0.1
NZ_CP015409.2|WP_084042737.1|1428119_1430591_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	4.3e-54	178.6	0.0
NZ_CP015409.2|WP_065529291.1|1433359_1434184_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	8.8e-98	321.8	0.1
NZ_CP015409.2|WP_065529289.1|1430613_1431309_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	4.4e-63	207.4	0.0
NZ_CP015409.2|WP_065529286.1|1426338_1427358_-|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	1.9e-135	446.0	0.0
NZ_CP015409.2|WP_065529290.1|1431325_1433317_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	8.5e-143	471.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP015409.2|WP_031931505.1|1449605_1450202_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	5.00071e-29
NZ_CP015409.2|WP_065529287.1|1427354_1428023_-|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	4.2264e-45
NZ_CP015409.2|WP_031931498.1|1442256_1442706_-|KH-domain-containing-protein	gnl|CDD|224760	COG1847, Jag, Predicted RNA-binding protein [General function prediction only].	4.91528e-30
NZ_CP015409.2|WP_065529298.1|1448724_1449300_-|rubrerythrin-family-protein	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	1.23379e-55
NZ_CP015409.2|WP_065529292.1|1435185_1436340_-|acyltransferase	gnl|CDD|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	1.98014e-16
NZ_CP015409.2|WP_051729719.1|1443230_1445486_+|catalase-HPII	gnl|CDD|236886	PRK11249, katE, hydroperoxidase II; Provisional.	0
NZ_CP015409.2|WP_084042737.1|1428119_1430591_+|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.04105e-44
NZ_CP015409.2|WP_065529283.1|1423843_1424137_+|hypothetical-protein	gnl|CDD|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	1.32258e-06
NZ_CP015409.2|WP_065529289.1|1430613_1431309_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	4.79232e-90
NZ_CP015409.2|WP_031931491.1|1423172_1423793_+|hypothetical-protein	gnl|CDD|222807	PHA00662, PHA00662, hypothetical protein.	9.5243e-22
NZ_CP015409.2|WP_065529285.1|1426033_1426324_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.15785e-31
NZ_CP015409.2|WP_065529286.1|1426338_1427358_-|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl|CDD|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	3.5402e-173
NZ_CP015409.2|WP_065529290.1|1431325_1433317_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	4.80679e-136
NZ_CP015409.2|WP_088358250.1|1445982_1448676_-|hypothetical-protein	gnl|CDD|274447	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB. Members of this protein family represent one of two essential proteins of system II for c-type cytochrome biogenesis. Additional proteins tend to be part of the system but can be replaced by chemical reductants such as dithiothreitol. This protein is designated CcsB in Bordetella pertussis and some other bacteria, resC in Bacillus (where there is additional N-terminal sequence), and CcsA in chloroplast. We use the CcsB designation here. Member sequences show regions of strong sequence conservation and variable-length, poorly conserved regions in between; sparsely filled columns were removed from the seed alignment prior to model construction. [Energy metabolism, Electron transport, Protein fate, Protein modification and repair].	1.80958e-34
NZ_CP015409.2|WP_065529293.1|1437520_1441102_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl|CDD|143443	cd07125, ALDH_PutA-P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA. The proline catabolic enzymes of the aldehyde dehydrogenase (ALDH) protein superfamily, proline dehydrogenase and Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH, (EC=1.5.1.12 )), catalyze the two-step oxidation of proline to glutamate; P5CDH catalyzes the oxidation of glutamate semialdehyde, utilizing NAD+ as the electron acceptor. In some bacteria, the two enzymes are fused into the bifunctional flavoenzyme, proline utilization A (PutA) These enzymes play important roles in cellular redox control, superoxide generation, and apoptosis. In certain prokaryotes such as Escherichia coli, PutA is also a transcriptional repressor of the proline utilization genes.	0
NZ_CP015409.2|WP_065529291.1|1433359_1434184_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.32846e-114

Protein sequences

>NZ_CP015409.2|WP_065529291.1|1433359_1434184_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSLNHKIDFAVIFTVTNANPNGDPLDGNRPRTTLEGLGEISDVCLKRKIRNKLMDMGQNIFVQSDDRRVDDYKTLKERATPILKQKGTSAELAQKACQEWYDVRAFGQVFALKDKDAAKGTGVSIGIRGPVTIQPAFSKDTVNITSTQITKSVSNDGDGSKKSSDTMGMKHRVDKGTYVFFGAINPQLAELTGFSDEDASIFKQVLPQMFEGDASSARPEGSMSIQKVIWWEHNCKSGQYSSAKVHHSIEISEDGNIVKKYDLPGLTPEMIEGF
>NZ_CP015409.2|WP_065529290.1|1431325_1433317_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MNWMYALYATYEQNRDYVGRIDKEPAHGNRKERLITPLLPLYHSMQNAHITITLNRQGELIDASLNNQNSQPTIIPVTEASGGRTSGACAHPLCDKLQYVAGDNADYFPPEKSPAKRTKQLKTLQASYEQYEQQLSEWAAFDPGNVKLNAVLAYIRKKSLIRDLIKKEILHVEDSTNTLLPVWKGDKQEMPAIFEFLGASTQENAFIRWKINNKDGNPPEVYEDPAMYESWRIYTESKANKEGMCYVLGKTAPLATTHPARIRNAGDKAKLISSNDSSGYTYRGRFIEADEACGVSTEVTQKAHSALRWLISRQGWYDGDLVVLAWSPGLLKVPSPCGNVQEWEHYTPDQPTPNDQVTQLVKQFKKELSGGGKELLRTSLNENDIKNRVLVLSLNSASPGRMSLSSFQEFTVSEYLNNLLSWHSKASWKQHLPKDKEGNDRSYIGAPSISMIVKAAYGIKVDDKLRKHALSRLLPCILYNLPIPPDLEKQCVIQASKRHAMEWWEWEMTLGVSCSVYLYNHPQTNTSSSDTMSLDPKITDRSYLFGRLLAVAEAIETSALNITKTSRPTNAEKLMQRFQQRPSETWSMLEKSIQPYRNILKKNENTVSFLRSYDAYIDNIMETFLMGQFMDNGPLTGAYLLGYHCQRAFIYKTKEEKNAELAK
>NZ_CP015409.2|WP_065529289.1|1430613_1431309_+|type-I-C-CRISPR-associated-protein-Cas5
MLNQIEFKVYGKYALFSDPLTRIGGEKCSYQIPTYEALKGIVKAVYWKPTLIWLIDEVRIMRPIRLVPKNMKLIKYHEAGADLSVYTYLQDVEYQVKAHFEWNMYRPDMSKDRIDGKHYEIARRMIDRGGRRDIALGTRECQGYVEPCRFGEGKGFYDQYGDTSFGLMFHGFNYPDETGKEELSIRFWRPVMENGKIRFVRPEACEIVKHVRPMAACPPRSSGLNDLSLGE
>NZ_CP015409.2|WP_084042737.1|1428119_1430591_+|CRISPR-associated-helicase/endonuclease-Cas3
MYQARPHQSLSTHEQECARTMSTLLAPLGLSQFGALIGGMHDFGKMSADFQQYMDALSQHISPPIPKGGIDHSTAGAQFVWNYFPIPEDSEEFFIFRQIIALCIASHHNSALIDCFRGTMPGDDVFSKRMEKSGEKTHLDEILSKLTFQEKEHYYSLLKKTELATEFKNVYTLLTTLFGHCPKKQAFHAGLIARFCLSSLIEADYTSASGKGSYESIPEPDWEGMLKNLNKHLEQFKADTPINQSRAAMSQECLQAAPGRVGKWNLTLPTGAGKTLSSLRFALEHARRHHLSRIIYIIPYTSILDQTANAIRKVLGNEYKDCILEHHSNLVKETLNKEGEMEPWSPERKTWYMEATQTWNVPIVLTTSVQYLNALYASGKQYVRRMHSLANAVVIFDEVQAIPPTSLRLFEHSLDFLAGICHSSTIRCTATPPETATEDGTHAHLIETPIIPDSQAYFDQFSQFRQCEVVCERKPSNYWTVEKMRDFIMEQASSKSPTLVIVNTKKLASKLACACQDLNTEADVFHLSTNMCPAHRKEIITNRIDKKSLEKARRKGKAVVCISTGLIEAGVDVDFDVIIRSVAGLDSCTQAAGRCNRDANRSGGRVILINPAGNLERLDFLPELEIGREIAMGMICDPEEGGILGNKSVSLYFKEFYGKLTRSHNHDHLSYPFICSNVATNMEDALSQNFKLMTHPRQQSKYAPLRLFQAFDSAARQYHPIKDDTIAVITPYGRGEECREKLWNMNPHTDEEWEQWNEWLQKARAYSVAISSQLLEKYLNSGDIMRIQEGVDIYTTIPNKYDPFLGFLTDPGETSGALTVSRI
>NZ_CP015409.2|WP_065529287.1|1427354_1428023_-|CRISPR-associated-protein-Cas4
MSSSFFSVPLAALQHYLYCPRQCALIHLECAWADNQFTAEGNVFHERADSGMTENRGRKRILRSLHISSLQWGIHGIADVVEVVYAEKGGIPVSMTPVEYKVGKPKPHRADEVQVCAQALCLEEMFGLEIPSGFLFYGKTQKRMEVVFDEELRILTAEAIRNAREVLTGEVTPPPMYSKACKSCSLVNDCLPDVCREHRQTMKARVDSVFEDSLETSEADDL
>NZ_CP015409.2|WP_065529286.1|1426338_1427358_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKHLNTLFVTLEGCWLSKDGDTVKVNAEGTCLLRVPLHNLEGIVTLGWDIGVSPYLMGACAERGITLSFCNPYGKFLAGVQGFMKGNILLRREQYRWADDEARWVGVAREMIGAKIANCRSLLLRAQRTYGKDLSEAIDRLAAFCSMARGCNSGDMLRGIEGSAAETYFSCLSHCQRTEDPELVFESRNRRPPKDCFNALLSFLYSLLCHDARSALESSGIDAAAGFLHRDRPGRPGMALDLMEEFRAPLADRLALTLINRKQISSDDFDKEESGAVFLKEDSRKKVLNAWQERKKTVLVHPFLQEKTTLGLLIHIQALLLARHLRGDLDCYTPFIGK
>NZ_CP015409.2|WP_065529285.1|1426033_1426324_-|CRISPR-associated-endonuclease-Cas2
MYILITYDVATDDKAGQRRLRQVARACENVGQRVQNSVFECELPPAQLVDIRNKLLKIIDSESDSLRIYHMGSNWHHKIEQLGKEKSYDIFGPLII
>NZ_CP015409.2|WP_065529284.1|1424133_1424391_+|hypothetical-protein
MKNPLLSTEEKRRWLARVFRDEDGEYSQADKFKALVEDTKLATLQQEEEEFKRQREMGAEPQDPILALLQSLPPAELNLNNHPSS
>NZ_CP015409.2|WP_065529283.1|1423843_1424137_+|hypothetical-protein
MKALDFIQIFASNVRRLDFRLSSAQVILAVIAGYRRHSTITEATRLHPNTVTNILQDLIAQGYVNRIGDGRPYVYRPTADGEQLAGNLLDKNTFPGI
>NZ_CP015409.2|WP_031931491.1|1423172_1423793_+|hypothetical-protein
MINESLLQPDTPSALDICNAALSKIGEAPLDALIANESTASRLCVLHYHPARRETLCMARWTFAATQTTLDSVSAQAPNSLTPYQFTLPADCLRVLDVECSEWKMQGRRIHASCAPLPLSYIADIENADQFDPLFMDALATRLAEKLAMPLTGNQSLRQNLNQEFHKIILPQAATVNAVQCFSNDSHPLLDLLRKIKSPSCPEECE
>NZ_CP015409.2|WP_065529292.1|1435185_1436340_-|acyltransferase
MNANQSLNSLGSHIAWVGFLRILACFLVVLAHCCDPFVGSFDGSFNFKSAVFWGSLVRPCVPLFAMISGVLLFPVTLEMGAFYSRRLKRVLVPLIVWSLALPLLYFGYFAAGVQTDSPNIVMDTYTWSATVGKLYTFFFNFNYDTTPLWYVYMLVGLYLFMPIMSAWLAQARRKDVKIFLGIWIFSMTLPYIQMLAPALGYEGNYGNMGILGVCDWNPYGMFYNFSGFLGYMVLAHYLTKYPLAWSWKKMLSITIPLFLIGFAVTFFGFLETQKHFPGQYSKLEVLWYFSGINVFLMTFAIFAVVSRLRIKAGPVLSKVAALTFGVYLCHFFFVQCSYDFVNFIGLGGLPSAVKIPLMACLASAVSAALVWLLSLNRWTRKSIM
>NZ_CP015409.2|WP_143246799.1|1436831_1437317_-|hypothetical-protein
MNASPKKLEMQNLKNNEASPSVNTFTYKVLRIIITTTILTIIYAFPADKEALSYYDLIIQSLILAFSSSLGIFYIIPFSFQALKRAKQSYILDSPSKTIAYALIVIVSMLSWYWITDSIIQSITGYPIEGLYHSKSPQYRYRYSKAYKIRAERLKIQRGEF
>NZ_CP015409.2|WP_065529293.1|1437520_1441102_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MTDSSIPDMMAEARRGQWTDQQLAAKAVELAEFILKQSNAGMRGKEKRQAQQMERMMNDPAGKAFTLALADRVFRPSSPARGAELFRYLLDGYGVPRYLSAADRFAMKMGGRFSAQFPGVVMPMITSQLRKESSNVILPAEDGKLRPHLRRRRKGGIRMNINQLGEAILGESEAHHRLQQVVDRLTDKDCDYISVKISAIFSQIHLVAFEETVKLIQERLRILYRAAITNAVTLPDGSRKPKFVNLDMEEYRDLHLTAEAFKRTLMEDEFMQLEAGIVLQAYLPDSWEEQMKLCAWAKERVEQGGARIKIRLVKGANLAMEKVEASMHGWAQAPYGTKAQVDANYKRMLHYGCMPDNARYVQFGVASHNLFDLCYAMLLREREGVRDQVEFEMLEGMANHQARVIRQAADGLLLYAPVVLKEDFHSAIAYLVRRLDENTSEENFLHDLFGMTPGSRSWEVQKKRFLKACQEKDEVKYGPNRTQNRAADPIQPSHYRDAFANERDTDWSLRQNAEWINGLIAAEKEKSGEEIPLVIDGEEITTNLWGVGRDPSRHNEVSYKFAYADFDQVEHALVTADRARSSWASKSIGERAEILHRAAQELSRIRGEAIAAMVRDAGKAPTEADVEVSEAIDFCRYYAEGLNRDGMNDGVEMSPLGTICVMSPWNFPFAIPTGGVAAALMAGNAVVFKPSELAVYTAWQIVQAFWRAGVPKNVLQFVPMPRNEISRKFLMDPRLNGVIMTGSYRTGKMLRELRPDLHVLAETSGKDAMIITATADPDQAVKDLVKSAFGHSGQKCSAASVAIVEASVYDNPAFLRQLKDAAASLKVGGSWEVNSVVTPLIREPEGNLLRALTQLEPGEEWLLKPEPSEDNPCLWSPGIRLGVKPGSWFHQTECFGPVLGIIRAENLEEAIDIQNDSEFGLTGGLQSLDEREIALWKTKVQVGNAYINRVITGAIVRRQPFGGWNHSSMGPGAKAGGPNYLTMLGSWEEKALPQKLRTPGERISGLVEKLCSELPDCAKRIRSAAGSQAKWWMEEFGVDHDPSRVYGENNIFRYTPVKGILARVENMSDDDVAILLLGAKLCGVLLHLSIGASRPWIQKMHGYYASLTVETEAELIGRMPEALQGVRFLRGTDISEALVNAAHARDVEVLDRPVLANGRLELLGYFREQAVSETVHRYGNLIPPPGSFKANRA
>NZ_CP015409.2|WP_102741624.1|1441261_1442239_-|hypothetical-protein
MRTLAVIAFLALAFPGRAEMDALSVSCSAAPSLPSPVLVVYGSEEPGSAEARWLKVLQPGTEERRALDEYVRDVQFVTVPRHPSVKDWEENGSLSRAAMHGVRMLPSVVFLDSKGRVFDLVEGGASAASLREKVSLLAEKAQRVRPVTRVNDIPQGGDPAAEASAICRELEQVPPEAWFRDYPGTMKRLEKLNCTVPAFLNAREAAFRLEKNRKTAELLGESFRACKASSIRTCLEAWRACADDPSLSVEERQLILLSMVHPLWVRLEEVLYREAHTPESEDAFNQAVAVLEEVRDMNRSSVCGRRAHQLREELRRARLAAARYD
>NZ_CP015409.2|WP_031931498.1|1442256_1442706_-|KH-domain-containing-protein
MTVQEIAEQSLKSLLASLGFSADIEVTETDGIVCLNISSPDSQYIIGGDGDRLDDLQYLVNRMIQRKMEDAPRVKVDCDHYRERNEARLLEKARSLAERVQESGKPMKMPPLNAYHRRLVHNALQSMEGIVTESEEGDSRYKRITIRKG
>NZ_CP015409.2|WP_051729719.1|1443230_1445486_+|catalase-HPII
MKKKKPPMEDSAAPFPNGKEAAPHYTDTIDPELIKPTPKPTPPNAEPSAPGSMKMPDNATEKIRELDAMRSNGMGQALTSNLGVKISDDQNTLKAGSRGPSLLEDFHFLEKMAHFDQERIPERVVHARGSGAHGYFQVYKSLSKYTKAAFLQDPGEKTPVFVRFSTVQGFRGSPDTVRDIRGWATKFYTKEGNYDLVGNNTPVFFIQDAIKFPDFVHAVKPEPHNEMPQGQTAHDSFWDFVSLQPETLHNVMWAMSDRGIPRSFRTMEGFGIHTYKLINEDGKSTFVRFHWKPLYGKKSLVWDEAQVLTGRDPDFHRKDLWQSIEAGDYPEYELGLQLIPEEDADQFDFDILDATKLIPEALVPVEIVGKMVLNRNPDNFFAETEQAAFCPANIVPGIDFSDDPLLQGRIFSYSDTQRHRLGGANFTEIPINRPICPFHNNQRDGFHRMQIDTSPANYDPNSIGNNWPRETPPEKGGFTTSPQTVSGVKERLRSPSFAEYYSHPRLFWMSQTPVEQEHIINAFSFELGKVTRPYIRERVVDLLTRIDPDLASGVARNLGIQLTREQLSRELPRPVCGLEQDPSLSLYAHTDGNLKGLRVSLLAADGVSLKSVKEICDALHEEGIHPQIIAPHMGSITTEEGEELFVDGTLSGTPSVLFDSVIVPEGEQSLTTLLKDGDAKYHLRQAYRHLKAIGLPGNAKAMLEAASLPQDTDDAGLLMPKDTKSLMPPFITAMKQHRVWSREPKTLDFGA
>NZ_CP015409.2|WP_088358250.1|1445982_1448676_-|hypothetical-protein
MQSALFLDYGCLTLMDRERTDAVWKKYGRSLWNFAGSYGLGIALMLILLVLTFAGTLHQVRLSSAMGSEAAIESFFGAAYVLIPLGGENSLISLPLPGMGITCVLLFANLLIGGVFRIRWTWRHAGVLVAHGGILLLLAGIMLGNKMTVAVEQVELPQGDRVHEYSLPFDLRLNRFVPEFYPGTSKPKSYESQITVFPESGGQYDAVIRMNEPLRLSGWTLYQMSWGQDSLHPGRLISILRASHNPLEQMPKWSSYIIALGLLWHFACVFGRYLRRKPGLASAGTAATVEPQAASVPGGKKHLRLAGICLLVAAIFGVGMLAARPAAHPVLVKNYVPWSPALVERAGAMAVQDGGRLKPVSTYAGFHLLRTLGKRSFVVDTPEGKRKLSPVEWMLDCMFRPELAEQYPVFLVNREEVVRRLHLPDQKDKRKKYSYAQLAERWEEMTRAVREIRLLGETNLTEAQKEILSLARNFDVMRGWMLVSRIMLENPSAMERMEFPRWFPSAGRDGERLWTAAPDKVAGAFLAMASLLERKAIGMEGAEASALRMKAEGLLLEKLAQPNEAASAGERHSLEREIFYYRLDPLYISLAVFVAAFVCLLLCALFRPAANAPLWRRFLRPGGFSLAWLTGAGGTGVLAAALVIRMLITMRSPVGNTYETIAFIACMGVLCALVVELFSKKGIVLAAGLLLGAFSCQMGILYEASQAVDHMDPLVAILRSNFLLSTHVITIVLGYAAGLLAAVLSHIYLLASPLCLISGKTEQSLDRMAYGILCFSLVFTLVGTVFGGIWGNESWGRFWGWDPKENGALMIVLWQLTVLHVRKAGWLSSWLLHFSNVVGGVIIAFAWWGVNMLGVGLHSYGFTSGRDALDMFYWFEAVLCVLFIILHYRALRRVDVR
>NZ_CP015409.2|WP_065529298.1|1448724_1449300_-|rubrerythrin-family-protein
MKSIKGTETEKNLLKAFAGESEARNRYTYFAGVAKKAGYEQIAAIFLETADNEKEHAKVFFKLLKDACVEVTHAVCTAPLESTEDCLLAAAAGEHDEWSDMYPAFAEVADREGFPAIAETFRKIASVEQHHEARYLRLAENVREGRVFAKEKEIQWKCRNCGYVHTGSTAPKVCPACAHPQAFFEELADNF
>NZ_CP015409.2|WP_031931505.1|1449605_1450202_+|GNAT-family-N-acetyltransferase
MNSANTPLLETERLILRKFTENDLEALFNIYSNEEVNTYLPWFPLTSLEEAASLFKEKYQEVYKRPYGYHYAICPKNSNLPAGYIHAGTDDSHDLGYGLLQEFWHRGFATEAARAVVARLKKDGMPYITATHDIRNPRSGGVMKQLGMRYQYSYEELWQPKNILVTFRMYQLNLDGQEDRVYQEYWNRSSVRFKETGI
>NZ_CP015409.2|WP_065529299.1|1450276_1450906_-|hypothetical-protein
MRRIVSLPVLAAFVVLGASCSQQVQQPVKKAAPPPVYVGKVEQVYPNHHYVLIALAGNVYEPGTVLISQSPGREEKCRVANLIVTEERMGRARIPADIRSGAVEAGDLVFLYRNLAVPESSGKMEEQKPGSPEPETDEDNKGVAPPVAPDGGRMADGLMPLPGEQPVPASADQERISREREKILRELERVPDRLEEPWSRTFSGKPVER

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP015409_1	1.18|1425699|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425699-1425732	34	NZ_CP015409.2	2130865-2130898	0	1.0

1. spacer 1.18|1425699|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to position: 2130865-2130898, mismatch: 0, identity: 1.0

cgagcatccccgtgatctgcctgtcccaggaagt	CRISPR spacer
cgagcatccccgtgatctgcctgtcccaggaagt	Protospacer
**********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015409_2	2.7|1434724|34|NZ_CP015409|CRISPRCasFinder,CRT,PILER-CR	1434724-1434757	34	NZ_AP021899	Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence	7631-7664	0	1.0
NZ_CP015409_1	1.13|1425362|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425362-1425395	34	NZ_AP021899	Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence	32729-32762	1	0.971
NZ_CP015409_1	1.14|1425429|35|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425429-1425463	35	NZ_AP021899	Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence	53-87	1	0.971
NZ_CP015409_1	1.1|1424559|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424559-1424592	34	NZ_AP021899	Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence	8181-8214	3	0.912
NZ_CP015409_1	1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425497-1425530	34	NZ_CP023152	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence	52231-52264	7	0.794
NZ_CP015409_1	1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425497-1425530	34	NZ_AP012556	Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence	87853-87886	7	0.794
NZ_CP015409_1	1.14|1425429|35|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425429-1425463	35	MG000860	Bacillus phage BSP9, complete genome	138946-138980	8	0.771
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021334	Marinobacter salarius strain HL2708#2 plasmid pHL2708Z5, complete sequence	8453-8486	9	0.735
NZ_CP015409_1	1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425497-1425530	34	NZ_LR594668	Variovorax sp. SRS16 plasmid 3	277223-277256	9	0.735
NZ_CP015409_1	1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425497-1425530	34	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	950780-950813	9	0.735
NZ_CP015409_1	1.12|1425295|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425295-1425328	34	MT601272	Bacillus phage vB_BsuS-Goe11, complete genome	48849-48882	10	0.706
NZ_CP015409_1	1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425497-1425530	34	NZ_CP029339	Streptomyces sp. SM17 plasmid pSM17A, complete sequence	88379-88412	10	0.706
NZ_CP015409_1	1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1425497-1425530	34	NZ_CP026489	Streptomyces sp. 604F plasmid unnamed, complete sequence	103199-103232	10	0.706
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	1006235-1006268	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	990981-991014	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	585042-585075	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	997821-997854	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	985282-985315	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1655405-1655438	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	1341479-1341512	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	1250317-1250350	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	910878-910911	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	109177-109210	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	1149787-1149820	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	1009423-1009456	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	733259-733292	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	703034-703067	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	800802-800835	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	304946-304979	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	421806-421839	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	1637718-1637751	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	20940-20973	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	875003-875036	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	648701-648734	11	0.676
NZ_CP015409_1	1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT	1424826-1424859	34	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	733261-733294	11	0.676

1. spacer 2.7|1434724|34|NZ_CP015409|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP021899 (Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence) position: , mismatch: 0, identity: 1.0

tatatatttttgtatccataaaacagttttgtaa	CRISPR spacer
tatatatttttgtatccataaaacagttttgtaa	Protospacer
**********************************

2. spacer 1.13|1425362|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP021899 (Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence) position: , mismatch: 1, identity: 0.971

caacatggaggactattgacatgagcctgtccaa	CRISPR spacer
caacatggaggactattgaaatgagcctgtccaa	Protospacer
******************* **************

3. spacer 1.14|1425429|35|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP021899 (Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence) position: , mismatch: 1, identity: 0.971

aaggggaaactccgtggaacaacgctccgtcccct	CRISPR spacer
aaggggaaactccgtggaacaacgctccgtccccc	Protospacer
**********************************.

4. spacer 1.1|1424559|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP021899 (Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence) position: , mismatch: 3, identity: 0.912

cggcgccctccgtatctttctgcacccgcacctg	CRISPR spacer
tggctccctccgtatctttctgtacccgcacctg	Protospacer
.*** *****************.***********

5. spacer 1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023152 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence) position: , mismatch: 7, identity: 0.794

ggatgccggggatgatgtggccgaccgcaacaac	CRISPR spacer
tgatgccggggatgatgtcgccgagcgacatgac	Protospacer
 ***************** ***** **  *..**

6. spacer 1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP012556 (Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence) position: , mismatch: 7, identity: 0.794

ggatgccggggatgatgtggccgaccgcaacaac	CRISPR spacer
tgatgccggggatgatgtcgccgagcgacatgac	Protospacer
 ***************** ***** **  *..**

7. spacer 1.14|1425429|35|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to MG000860 (Bacillus phage BSP9, complete genome) position: , mismatch: 8, identity: 0.771

aaggggaaactccgtggaacaacgctccgtcccct	CRISPR spacer
atggggacactgcgtggaacaacgctcactctgcc	Protospacer
* ***** *** ***************  **. *.

8. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021334 (Marinobacter salarius strain HL2708#2 plasmid pHL2708Z5, complete sequence) position: , mismatch: 9, identity: 0.735

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
cgcccagccgctggcgctggaggaggcatactcc	Protospacer
*..*.  .*** ******** ************ 

9. spacer 1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594668 (Variovorax sp. SRS16 plasmid 3) position: , mismatch: 9, identity: 0.735

ggatgccggggatgatgtggccgaccgcaacaac	CRISPR spacer
ggatgctggggatgatctggccgaccacgctgga	Protospacer
******.********* *********.*. ... 

10. spacer 1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 9, identity: 0.735

ggatgccggggatgatgtggccgaccgcaacaac	CRISPR spacer
cgatgccgtcgatgatgtggccgacgccggagac	Protospacer
 *******  ***************  *.. .**

11. spacer 1.12|1425295|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to MT601272 (Bacillus phage vB_BsuS-Goe11, complete genome) position: , mismatch: 10, identity: 0.706

ggatccccgccaaaatcaacattcaaaccctcaa	CRISPR spacer
ttatccccgctaaaatcaacaatcaagaagtcgt	Protospacer
  ********.********** ****.   **. 

12. spacer 1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029339 (Streptomyces sp. SM17 plasmid pSM17A, complete sequence) position: , mismatch: 10, identity: 0.706

ggatgccggggatgatgtggccgaccgcaacaac	CRISPR spacer
tgttgccgggggtgaggtggccgaccggtcgggc	Protospacer
 * ********.*** ***********    ..*

13. spacer 1.15|1425497|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026489 (Streptomyces sp. 604F plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

ggatgccggggatgatgtggccgaccgcaacaac	CRISPR spacer
tgttgccgggggtgaggtggccgaccggtcgggc	Protospacer
 * ********.*** ***********    ..*

14. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

15. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

16. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

17. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

18. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

19. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

20. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

21. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

22. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

23. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

24. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

25. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

26. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

27. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

28. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

29. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

30. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

31. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

32. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

33. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

34. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

35. spacer 1.5|1424826|34|NZ_CP015409|PILER-CR,CRISPRCasFinder,CRT matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 11, identity: 0.676

catcttttcgcgggcgctggtggaggcatactcg	CRISPR spacer
ggccttttcgcgggcgccgggggaggcgatcgat	Protospacer
 ..**************.** ******.  *   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2560117 : 2567634	9	Diadromus_pulchellus_ascovirus(16.67%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP015409|2560117:2567634|DBSCAN-SWA
AATGAGCACAGAAGGCACTAACAAAATACAGAACCCGCGCGGTGAATTCCAACAGGAAAGATATGAAAAGCAGCAGCAGAAAGCCCCCGGACTGCAATCCGGAATGAAGCCCGTGCCGGATTCCGGGGAACAAAGCTACCATGGCTGCAACAGGCTCCGTGGACGAAAAGCCCTGGTCACAGGGGGAGACTCGGGAATAGGCCGGGCGGCGGCTATTGCCTACGCACGCGAAGGAGCCGACGTAGCCTTGAACTACCTTCCTGAAGAACAAAGCGATGCCGAAGAAGTGGCGGAACTCATCAGAAAAGAGGGCCGGAAGGCTGTCCTGCTGCCGGGGGACCTCAGCAATGAAGTCTTTTGTAAAAAACTCGTCAGGGATGCCTTGGAAAAACTTGGCGGACTGGACATCATGGCCCTGGTAGCCGGTAAACAAGTGGCGGTGGAAGATATCCGGGACATTACCACGGAACAATTAACCAAGACATTTGAAGTAAACGTGTTCTCCCTGTTCTGGATTGCCAAGGAAGCCCTTCCGCATCTCAAGCCGGGGACGAGCATCATTACCTGCTCCTCCATTCAGGCCTACCAGCCCGGCAAGAACCTGGTGGACTATGCTTCCACAAAAGCGGCCATCATCGCGTTCAGCCGCTCCCTGGCCAAGCAGGTTGCCCCCAAAGGCATCCGGGTCAACGTGGTGGCTCCCGGCCCCATCTGGACAGCCCTGCAAGTAACCGGAGGCCAGCTGCAGAAGGACCTGCCGGAATTCGGACGGAAAACGCCTCTCAAAAGGGCAGGGCAACCTGTGGAACTCTCCGGACTATACGTCTTTCTCGCCTCCCAGGAATCCAGCTTCATTACTGCGGAGGTCTTTGGCGTTACCGGCGGCATGCATCTGGCCTGATGCGGAAACTCGCAATCCTGGAAAAGGGCCGGACTGACTTTCCGGAATCCCTTTCCGCAGCGCCACACCCCCGGATGACCGGGAAAGCGGCCGGAAACGGCTCTGCAAGGAAATCAGGGCATTGCTCCATTTCCCGGTTGTCCTGGCAAAAGGTTTCTGCTTGAATAGGGTAATGGCATTTTGGAGGTTTTGGTTCATCTTTTTCCCTTTCACGGCGCTTCTCTTTTCCATGGTGCATGGCAGTCCTCTGAACGCACCCGTCATCACCCTTGGAGAGAAAAAAAGCCTGTTCGGAGAAAAAGCGCAGGCCAATGAATATGTCAGCTATGCCCTTTATTACTGGCCGGACCCCGCCAATCCGGACGGTCCTTACAAACCCATTGACGGCAAAAAGAACAAACGGCTCCGCAGCATGGACGACAGCGGCAGGATGGCCGCTTTCATCGGCACGGTCTGCAACCTGGGACGGCAGTATAAACTCGACAGGGATCCGCAGGCCGCCTCCCGGGCCGGGCAATGGCTGAAAGCCTGGTTCATTGCTCCGGCAACCCGCATGCAGCCCCATCTGAAATATGCCCAAATTCGCCCCGGACACCGGACGGAAGGAGACGGAGGAGGCATCATCGACCTTTACCGCATGCCCGAATTCCTGGAAGCTTTGACGGCGTTGAAATGCTCCAATGCCCTAACGGCAGAAGAATGGAAGCAGGTGGGCGCGTGGCTGAACCAGTATTACACATGGCTGACTACCAGCAGGCAGGGCAGGCATGCACACACGCGCAGCAACAACCATTATCTGTTTTATGTGGCGCAATGCGCCCATTTGGCATCCTTCCTGGGCCGCAGCCATGAAGCGGCCCAATGGCTGGCGGAAGCCTTCGCCAACATGGACCGCCACATCGCTCCCGACGGATCCCAGCCCGAAGAACTCAAACGGGCGGAACCCTGGCAATACAGCGTTTACACTCTTCAGGCATGGGGATACCTGGTGCATCTTGCAGAACGCATGGGCGACAAGAACTACCGTTACCGGAAAACACCCGCCGAGGCTTCCATTCAAAAAGCTGTGGATTATCTCCTGCCTTACCGCGCCAACCCTGAAACATGGCCCTGGCAAGGCTCCAAGGCAAACACTCCGCTGCCCGCCATCTTTGAACCGGAGCAGGCGGGCAGGCCACAACGGAAATGCTCCTGAACCGCGCCCGCCGTTAAAAGTATCCGTTTTTCCTGCTTATTGAAAATCCCCTCTCCAGCAGCACGAACGGGGCATTTTCCCGGAAAACGATTTAATAAGGGATCTCCCCAGTATTTTTCCCCTTAGATTTTTCCTTTCTTTTTGCTGCTTTCCATTCCCACGGAGATATGGGATTCGGCTCAGACCAGATGCCTTTTTGGGCCTTTCTGGCATCCCTTTCAAGAGAAACGAGCTTCCGGCTGGCGGAAAAATTTTTATAAATCCACGCCCATCCTTCCTTCACCATCTCTTCGTTGACGAACATTTTTCCATGCCATATTTCCCCTAAAATACGGCCGTACCTGTCATTCTCGGTATACCGGACTGTAACCGTCTCTCCCCAAATCAGCTTTTCCAGGTATTCCTTGGCGCCTTCATACCCGTCCTGCCCCCTTTCCGGCGTATCAATTCCCTCAAGCCGTATCCGGTGCGTACGCATTTGTTCAGGCGTCCTTTCCAGAAGGATGACCGTGTCGCCGTCAATCACGTTAATCACGACTCCCCTGATACTTTCAGCAAAAGCCATGCAGGGACTTATCAGGAAAATCAAAAGCCATTTCATGAAAAATGATATAATCCAAAAAATATCAGGATGCAACTACTCTTTAGAGAAACCGTTCCCGCACTGTTCACACGGCCGGAAACAGATGAATGCGGTCATCTGTGGACAGCCTGTTCTGGAACAGGCCATCATGTTTTCCGGCATGAAGGAACACAATTCCCGAACCTATTCCAACCTGTCCGGAACAACGGTAAACAGGCTGTATCATTGCCCCGCTCCGGAACATCTTTATTCGCTGCCGTGCCAGGAGCGGAAGAACATCCCGCCGGCGCACCCCGGCAATCTAACCCATGCCGCCATTTAAAAAGACTGCACATTAAACAAGAAAAACCGGGCGCCCTGCAACATTCAATGGCATGGCGTGAGGCATTTTACTCATTTTTTCAATTCTTCGGCTATTCTGCCGAGGTTCTTTTCCGTTGCCTTTCTCAGTTTCTCCTGCTGTTTCCAGTACCATGCCGTTCTTTCCGACACCCCGGCCTGATTCGCCAGCCAACGCACGGCGCCGCTCGTGTCACAGCCTGTTTTCTTCTGAATGACTTCCAGCAGTTGAGCGACATATTTATTCATGGATTCCGGGTTGATATTATTTCGATTCCCATGCCCGGCTGAATTCCTCGTCCCGGAACAGGGAGGCAATCCCGCTGAGCTGCTTGAGGCGCAACAATTCTTCCGCATCCATCCCCAGATTTTTGAGTATCCACGCATCCGACATGCCTGCCTCCGTCAACTCCTGGATAATATTGGTCATGAGGGCGATATTATGAGATCCCCGGGCACGGTTGTGCCTGATGGTGGAAGCCATGCGGTTTCCAAGAGGCTTGTCGATTACGGCCACCGGCATCATGCCACCCTCCCGTTCGTAAATATCGCGGTAAGTCTTCATGATCTGGCAGCGGTGGAACCCGTCCACGATTTCATAGGTCCCGTCCTCCAGCTTATAACAAACGATAGGCATCGTATAACCGTCCTCCTTGATGCTCTGGTAGAGCAGCTTCATTTCGGGGGGAGCTACGCTGTTCGGGTTATAGGCATTGGAACGTATCTGGTCCAGGGGAACGCGCCGGATTTTGTAAACGGGGGATTGATAGGAGGTTTTCATAAAATATTGCGGTATTTATTGACGGCGGCCCGGCGCCGGGCAATCGCTCCCTTGGTTGGACCGAACCCGGCGTACTTGCAAAAGTAATCATTCTTCATGATGCAGATGCACATGCGCTTGTAGGAAGGCACCTGCCGGAAATTGCTGACCGGCATGTCGTCGGGATAGCCCATAAACTGAATGACGTCGCGGTCGACGTAACGGCCCGACTTCCCCGTCACGGTCGCCAGAGGATAGGCGGCCAGCACTTCATCGGCAGTTCCGGGATCGACGGTGCCCCCTTTCATCCAGTACTTTTTAGACCTCTCCAAAATGTTGTTGTAGTGTTCCGCCGTTTTCTCGTTCATTGTGGAAAGCAGGAATTCATAATAGGACTTCCAGGTATGGCCGGGCGGCAGTTTGATGGTTTTCCAGCCCATGGCCGTCGTACCTCCGTACAAACCTGTGAAGTTGACGCCGTTGACGCGCCCGACCATGCGCGCCCAGTTGGCAGGATCAATAACTTTGTAAAGCTTCAGGCTTTCCTGGGCGCAGTCATTAAACGGGCTTGCCACCCGCATTTGCCCGATCGTAAGGCCTGCCTGGTACAGGAGATCGTAAAGGCGGTTATAGTCAAAACCAAAACGGGCGTTGGCCGTCCAGACGTCACTGACGCGCCAGTCATAAAGAGGGTAGGCGCTGACGGTCACGGCATCAGCCCGTGTAATCCACTTCCTTCCCTCATAAGACGTCCTTTTATTGCCGCGGGCAACGGCGGCGTATCTGTTGAGGCTTTCATCCGCCCGCAGCCCTACCATGACGGCAGTACTTCCGTGTTTTTTGGCAAAATGGCGTGAAAGCTTATCCTGGAATTCATAGTCCACCATACCGTGCCGGAACGGGACGTCCAGATTCTTTTCATTGATTACATAGGGATTTTCCGGCATGGGTCGCACCCACAGTTTTTTCTGGGCGGCGCTCCACGGCGTCCAGTAAGGTTCCCCCAGGGAGCATGCGGACTGGGCCCTGATCGGTACACAGTACCACATCTTACGAATGCCGGGGAATTGCTCCAGAAATGTTCTGGTGACATACTCGGTCGTCATCTGATATTGGGCCTCATAATCAAGGTGATACATGGACAGCTTATCCAGAAGGCCCTGTTCGGCGGCGTAACGATAGCAGAGATTAAGCATGACGCCGCTGTCCTTGCCGCCCGAAAAAGACACCAGGACATTGTCAAACTCTTGGAAACAATAGGCTATGCGTTCTAAAGCCGCCTCATAAACATTTTTATCCAGATATGTTTTCACAACTTTTCCAAAGCCTGTCTTTCGCCATCCGCCGCCAGCCCCCTGCCGGACGGGAACACGTCGGCCCGGATATGATCGCCGGAAGCCATGCATTTTCCCTGAAACCACTCTTGCAGCTTGCAGCTCATAGGGATATCCCCTGTTCTTTCAAACAGGGTTGCAACGCCTTCATTTCTGCATAAATAAGCAACATCATGTTTTTTCATGTTTTCAAATGCGCAGCAGCTTATCGTCCGTTATTTTCCGTCAACAATACCAACCTACTGAATTATTGCGGCGGGTCAATGTTTTTACTGCAATTATTTCAGTAATTTTATTGTCATCACCCTCCTTCTCAAAATACCTGCGCTTTTTAGCGAGCAACACCATTCCAGAAATGCCTTATGCATTGCGCCATGACCTCCTTTCCTTCTCCGCAACATCTGCGCTATGTGCAGCATTCAAGACGCTACGTTGGAATACACGGTTTCAGAATCGGAGACACAGCAATCATAACTTGCTTAAAATTAGCGTGAACGAAAAAAATGTACGGCTCAGAGCCATTTTCCGGTTCCAACATCTTTCCCCCAATACTCTTTCCGGAACCGCATCTTCCAGGCAGACGATACATCCATCATTTCCCTCCTGAAGGAAAAACAACCGTGTTTCCCTTTTTGCAATCCGGGATGCTGTCCAAACATGAATATGCCGGTACACGCCTTAATCATGCCGCCAGATTAGACTTTAGGCGTTTTATGATTTTCCCCGAAACGCCAATTTCATGCCAGAACGGAATCAAAAAATGACATTTAGTCAGCACTTATGGTTGTTTTTCCGCGGTTTTTCACCTTTCCAGCCTCAAAACAGACAAAAAAGAAGCCCTGTAATCCATTAAAATTACAGGGTTTAGAAAATTAGTGGCTCCCCCGGTTGGGCTCGAACCAACGACCTAGTGATTAACAGAGAACTAATAAATACGCATAATATATTTATTATTATAATATTACATTTTTATCATTACGCCAATATTACGCCACAGAGAATTTTAAACGTGAAGATTTATGCCCGTTTATTATCGTTTCTCGTATTTCTTTTTGTATGGAAGTGGCGTTCCAAGTTTATCAGGCTTGGAGAAGTTCGGGATGCTTGCTGACAAGCTCCAGAAGGCGGGCAGAAGAACCACTGGGCCGCCGCTGACCACTTTCCCATTTAATCAGCGTTGAAAGACTCACTCCCAGCAGCCGCGCAAAATCTTTCTGTGTGACGCCCCGGGACTGACGAAGCTGGGCGATGGCGTTTTCATTGGCCCATGCGCGGGACTTGCCGGGTACGATGACCGCTGCCCGGGGTTCAGGCAGGGGAGTTCCATCCGTCAGGCAGTCTTCCACATATAATTCCGCACACTCATCCAGATTTCGAGCTACTTCCTCCACAGTGCTTCCATGGGTGCAATCTCCATCAAATTCAGGCAGGGAACCAACAAAGCATTCATCCTCGTCGCTCCATCTGATAAGCCTTGCGTAAGGACGGGCAAGACGTTTTATTTCATTTTGATTCATGATTTTCCGATTTCGTCTTTGTCCGGGAACAATTCTTTTTTTCTATGGATAGCCTGGATGATTGTTCTATTCGCTTTTCATCTGATTTGACACGTCTTTCCAACTTCTTGATATCTTCTTCAGGGGGGAGTTTCTCTGGATGGATTCCACGTCCCACCAACATTTCACGAACTCCCTTGTTGTTTTGTATGTGTTCACGTGTAATGTTTGGTTCTCCTTGGAGATCATTTGCTTCTACATTGTAGTTAGTCATTTCAGTAGCCAGACTCTTTGCCGCAATGGTTACAGAAGGAAGGAAATCTGCCAAAGGTCGATTCTGAGGCATTGCCAACTGGTTTTTCATCTGACTTGTTGTTTTTCCTCCAAAAAGAGCCTGGTCACCTTTAGCCCTAATGCGTCCAAAGCCTGCATCATCTACCCCTCGTTCATAAATATTTTGGGATAGCCGTTTTTCGGATTCCTTGAGCTTTTCCCTTGCTTCAAGACGCGTCAGCAGGTTCATACGGTCTTGAATCAATTCTTGCCGCCTTGTTTGAACCGCAAAATAGCACTGCGCAAAAGCTATTTCCTTTTTGGACGGATCGCCGTTTTGTGCAATGAGGTAGCAGGCATAACGGGTGAGTTTATAATCTAACACTTCCCGTTGCCCGCCCTTCCCTACGACGATCATTTTGTTGACTTCAACAAAATGATCGGAACATTGAAAGCCAGACGTTTTGCATGATTGTTTCGCTCTATCAATCGCAGTTTCAAAGTTACGCCATTCTTTGTACCCCAAATAGGGTTGTAGATCGCGAGCGTACCAGAATTCTACTGACGCTTCCGAATCCGTGCGGACAATGGAATCAAAATGGCTTTGCAAGATAGTTATTTGATCGTCGTTATTCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP015409|2560117:2567634|2563911_2565300_-|WP_099421487.1|DBSCAN-SWA
MHGFRRSYPGRRVPVRQGAGGGWRKTGFGKVVKTYLDKNVYEAALERIAYCFQEFDNVLVSFSGGKDSGVMLNLCYRYAAEQGLLDKLSMYHLDYEAQYQMTTEYVTRTFLEQFPGIRKMWYCVPIRAQSACSLGEPYWTPWSAAQKKLWVRPMPENPYVINEKNLDVPFRHGMVDYEFQDKLSRHFAKKHGSTAVMVGLRADESLNRYAAVARGNKRTSYEGRKWITRADAVTVSAYPLYDWRVSDVWTANARFGFDYNRLYDLLYQAGLTIGQMRVASPFNDCAQESLKLYKVIDPANWARMVGRVNGVNFTGLYGGTTAMGWKTIKLPPGHTWKSYYEFLLSTMNEKTAEHYNNILERSKKYWMKGGTVDPGTADEVLAAYPLATVTGKSGRYVDRDVIQFMGYPDDMPVSNFRQVPSYKRMCICIMKNDYFCKYAGFGPTKGAIARRRAAVNKYRNIL
>NZ_CP015409|2560117:2567634|2566731_2567634_-|WP_065530095.1|DBSCAN-SWA
MNNDDQITILQSHFDSIVRTDSEASVEFWYARDLQPYLGYKEWRNFETAIDRAKQSCKTSGFQCSDHFVEVNKMIVVGKGGQREVLDYKLTRYACYLIAQNGDPSKKEIAFAQCYFAVQTRRQELIQDRMNLLTRLEAREKLKESEKRLSQNIYERGVDDAGFGRIRAKGDQALFGGKTTSQMKNQLAMPQNRPLADFLPSVTIAAKSLATEMTNYNVEANDLQGEPNITREHIQNNKGVREMLVGRGIHPEKLPPEEDIKKLERRVKSDEKRIEQSSRLSIEKKNCSRTKTKSENHESK
>NZ_CP015409|2560117:2567634|2562303_2562813_-|WP_065530094.1|DBSCAN-SWA
MKWLLIFLISPCMAFAESIRGVVINVIDGDTVILLERTPEQMRTHRIRLEGIDTPERGQDGYEGAKEYLEKLIWGETVTVRYTENDRYGRILGEIWHGKMFVNEEMVKEGWAWIYKNFSASRKLVSLERDARKAQKGIWSEPNPISPWEWKAAKRKEKSKGKNTGEIPY
>NZ_CP015409|2560117:2567634|2561189_2562212_+|WP_065529869.1|DBSCAN-SWA
MAFWRFWFIFFPFTALLFSMVHGSPLNAPVITLGEKKSLFGEKAQANEYVSYALYYWPDPANPDGPYKPIDGKKNKRLRSMDDSGRMAAFIGTVCNLGRQYKLDRDPQAASRAGQWLKAWFIAPATRMQPHLKYAQIRPGHRTEGDGGGIIDLYRMPEFLEALTALKCSNALTAEEWKQVGAWLNQYYTWLTTSRQGRHAHTRSNNHYLFYVAQCAHLASFLGRSHEAAQWLAEAFANMDRHIAPDGSQPEELKRAEPWQYSVYTLQAWGYLVHLAERMGDKNYRYRKTPAEASIQKAVDYLLPYRANPETWPWQGSKANTPLPAIFEPEQAGRPQRKCS
>NZ_CP015409|2560117:2567634|2563188_2563383_-|WP_012419830.1|DBSCAN-SWA
MNKYVAQLLEVIQKKTGCDTSGAVRWLANQAGVSERTAWYWKQQEKLRKATEKNLGRIAEELKK
>NZ_CP015409|2560117:2567634|2562898_2563117_+|WP_065529870.1|DBSCAN-SWA
MNAVICGQPVLEQAIMFSGMKEHNSRTYSNLSGTTVNRLYHCPAPEHLYSLPCQERKNIPPAHPGNLTHAAI
>NZ_CP015409|2560117:2567634|2560117_2561017_+|WP_088358325.1|DBSCAN-SWA
MSTEGTNKIQNPRGEFQQERYEKQQQKAPGLQSGMKPVPDSGEQSYHGCNRLRGRKALVTGGDSGIGRAAAIAYAREGADVALNYLPEEQSDAEEVAELIRKEGRKAVLLPGDLSNEVFCKKLVRDALEKLGGLDIMALVAGKQVAVEDIRDITTEQLTKTFEVNVFSLFWIAKEALPHLKPGTSIITCSSIQAYQPGKNLVDYASTKAAIIAFSRSLAKQVAPKGIRVNVVAPGPIWTALQVTGGQLQKDLPEFGRKTPLKRAGQPVELSGLYVFLASQESSFITAEVFGVTGGMHLA
>NZ_CP015409|2560117:2567634|2563399_2563915_-|WP_012419831.1|DBSCAN-SWA
MKTSYQSPVYKIRRVPLDQIRSNAYNPNSVAPPEMKLLYQSIKEDGYTMPIVCYKLEDGTYEIVDGFHRCQIMKTYRDIYEREGGMMPVAVIDKPLGNRMASTIRHNRARGSHNIALMTNIIQELTEAGMSDAWILKNLGMDAEELLRLKQLSGIASLFRDEEFSRAWESK
>NZ_CP015409|2560117:2567634|2566307_2566745_-|WP_065529871.1|DBSCAN-SWA
MNQNEIKRLARPYARLIRWSDEDECFVGSLPEFDGDCTHGSTVEEVARNLDECAELYVEDCLTDGTPLPEPRAAVIVPGKSRAWANENAIAQLRQSRGVTQKDFARLLGVSLSTLIKWESGQRRPSGSSARLLELVSKHPELLQA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088358325.1|2560117_2561017_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	1.5e-61	45.7
WP_065529869.1|2561189_2562212_+	alginate lyase family protein	NA	NA	NA	NA
WP_065530094.1|2562303_2562813_-	thermonuclease family protein	I6T7L7	Staphylococcus_virus	2.6e-10	38.2
WP_065529870.1|2562898_2563117_+	hypothetical protein	NA	NA	NA	NA
WP_012419830.1|2563188_2563383_-	hypothetical protein	NA	NA	NA	NA
WP_012419831.1|2563399_2563915_-	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	1.4e-67	73.1
WP_099421487.1|2563911_2565300_-	DUF3440 domain-containing protein	L0P6Z6	Lactobacillus_phage	4.0e-130	51.0
WP_065529871.1|2566307_2566745_-	helix-turn-helix domain-containing protein	G9BWD3	Planktothrix_phage	5.6e-06	40.3
WP_065530095.1|2566731_2567634_-	DNA damage-inducible protein D	A0A2H4J297	uncultured_Caudovirales_phage	5.5e-24	43.2